LOCUS       DAOTIN010000001        91577 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_182_length_91577_cov_9.274349, whole genome shotgun sequence.
ACCESSION   DAOTIN010000001 DAOTIN010000000
VERSION     DAOTIN010000001.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 91577)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 91577)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..91577
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_182_length_91577_cov_9.274349"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            222..2225
                     /locus_tag="P5537_00005"
     CDS             222..2225
                     /locus_tag="P5537_00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004377840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl/propionyl/methylcrotonyl-CoA carboxylase
                     subunit alpha"
                     /protein_id="HRV76452.1"
                     /translation="MFDKILIANRGEIACRVIKTARRMGIKTVAVYSEADANARHVRL
                     ADEAVLIGPAAARESYLVIDKIIAAAKATGAQAIHPGYGFLSENEDFCHACEREGIVF
                     IGPPVSAIRAMGSKSEAKKLMEAAGVPLTPGYHGDDQEPSYLHQQADAIGYPVLIKAA
                     AGGGGKGMRLVEKSADFIDLLASCKREASSSFGDDHVLVEKYITKPRHIEIQVFGDTH
                     GNVVYLFERDCSVQRRHQKVLEEAPAPGMTLERRAAMGKAAVDAAKAVGYVGAGTVEF
                     IANQDGSFYFMEMNTRLQVEHPVTEMITGLDLVEWQLRVASGEKLPLEQEQLQIRGHA
                     LEARIYAEDPAKGFLPSTGKLVHLAPPAESLHVRVDTGVEEGDEISPHYDPMIAKLIV
                     WDINRDRALARMLQALADYRVVGVANNIEFLSRLTACPAFAGADLDTGLIEREKAYLF
                     PAEEGLPAEVLQIAALAELLRDAAFADRRAARSADPASPWHARDGWRMNATACRSLLF
                     RHGESEHEVEVAYLPGAWRLTVGGCSVVARGELNLRGLLRVELDGTRMDATVIAAAGR
                     RHVFAKGRAWQLAAVDPLHHGGEGGGAEGGLMAPMPGKVIALVAAEGAKVEKGAPLLI
                     LEAMKMEHTITAPAAGTVKAFRFGVGDQVGDGAELVEFEAAAA"
     gene            2432..4120
                     /locus_tag="P5537_00010"
     CDS             2432..4120
                     /locus_tag="P5537_00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004377841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HRV76453.1"
                     /translation="MSTQSYVHGASDKQLIGQTIGRFFDDACARHAEREALVVRHQGV
                     RLTYAQLKSRVDALACGLMRLGLAPGERIGIWSQNNMEWALTQFASAKAGLVLVNINP
                     AYRRSELEYALNKVGCRALVLSPAFKTSNYLEMIADLAPELGHCEPGLLRSHRLPALE
                     MVIRMGADKSPGMLSFDDLLRAPSREELTALAVLSEKLQFDDPINIQFTSGTTGHPKG
                     ATLSHHNILNNGFFVGEAIKLVPGDRLCIPVPLYHCFGMVMGNLGCLTHGATMVYPAE
                     AFEPLAVLETVAQEKCTGLYGVPTMFIAALDHPRFADFDLSSLRTGIMAGSPCPIEVM
                     KRVIGKMNMAEVTIAYGMTETSPVSFQSGTDDPIDRRVSTVGRVQPHLEVKIVDNEGR
                     IVPRGQSGELCTRGYSVMLGYWDDEAKTKEAIDAGGWMHTGDLAVIDDEGFCNIVGRI
                     KDMVIRGGENIYPREIEEFLYAHPKVLDVQVVGIPDQRFGEELCAWIILREGERLSED
                     EVREYCKGQIAHYKIPRYIRFVDSFPMTVTGKIQKFLIRQRMKEELGLDEAKTA"
     gene            4137..5072
                     /locus_tag="P5537_00015"
     CDS             4137..5072
                     /locus_tag="P5537_00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004315436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="HRV76454.1"
                     /translation="MTTSKLPSAVRIVEMGPRDGLQNEKQLVSTDTKLELVRRLERAG
                     LKAIETTSFVSPKWVPQMGDNAELLPRVLAAAAPGVAYPVLTPNLKGFEAALAAGAHE
                     VAVFGAASESFSQKNINCSIAESLARFRPVTEAAHAAGVKVRGYVSCVVGCPYEGAIA
                     PQAVADVAATLLDMGCYEVSLGDTIGVGTPASIQRMLEAVAKRVPVDRLAGHYHDTYG
                     MAVANVYASLELGVAVFDASVGGLGGCPYAAGASGNVATEDVVWLLNGLGIDTGIDLD
                     VLVDTAAWISARLGRDPASRVARAVLAKRAKAACA"
     gene            5235..5435
                     /locus_tag="P5537_00020"
     CDS             5235..5435
                     /locus_tag="P5537_00020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004337386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1289 domain-containing protein"
                     /protein_id="HRV76455.1"
                     /translation="MSVPSPCTNICRMSPDTGWCEGCQRTIDEITRWSRTTDDDRRGI
                     LAAVAERREWLGAAGQPVETRA"
     gene            5432..5656
                     /locus_tag="P5537_00025"
     CDS             5432..5656
                     /locus_tag="P5537_00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1289 domain-containing protein"
                     /protein_id="HRV76456.1"
                     /translation="MSGDALCVGVCMIDWDAGVCLGCGRSADEINGMPASAPDTSAVA
                     QPDPAAVSAARQAGVPLPPNVAARVGEGSD"
     gene            5653..6573
                     /locus_tag="P5537_00030"
     CDS             5653..6573
                     /locus_tag="P5537_00030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HRV76457.1"
                     /translation="MSARPQLPAGVQVFERGWLSANNVLLFDGDEATLIDSGYLSHAD
                     QTVGLLRAALEGRQLRRLINTHSHSDHIGGNARVQRAFGCSITVPEGMARAVAEWDEE
                     ALLLSVGAQAGERFRHDETLAPGARFVAGELEWQAVAVPGHDMDALAYYNPERRILIS
                     GDALWRDGFGILFAEVMGQGDALGEARRTLEAIGRLAVDAVIPGHGAPFAEFDDALER
                     AFARIRAFEDDGARMARNAIRACITFKLLEVRSMALAELPRHLDETPLYRTANARYLG
                     LDADALAAWLVKELERAGVARSEDGALVVL"
     gene            6658..8112
                     /locus_tag="P5537_00035"
     CDS             6658..8112
                     /locus_tag="P5537_00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004307999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HRV76458.1"
                     /translation="MQATVDWINGWVWSPALIYLCLIVGLYFSIRTRFMQVRHIGEMV
                     RAMFRGKSSAAGVSSFQALTIALSGRVGTGNIAGVATAIGFGGPGAIFWMWMVAFLGA
                     ATAYIESALGQIYKTEHHGLYRGGPAYYIEKGLGWRAYAIVFAVATVFACGVLLPGVQ
                     TNSIAASMENAFGVAPAVTGTIIVILLGLIIFGGVRRIAQVTQVVVPFMALGYVLAAA
                     VVVALNVDKVPEVVGLILSSAFGLDAGFGAMIGLAIQWGVKRGVYSNEAGQGTGPHAA
                     AAAEVPHPAAQGLVQAFSVYVDTLFVCSATAFMVLITGTYNVTGPDGAQVFTGLANIS
                     AGTGFTQAAMEQVLPGFGSMFVAVALFFFAFTTVLAYYYIAETNVAYLTRNLRSEALI
                     FVLRVALIGSALYGCVRTSDLAWGLGDIGVGLMAWLNIVAILVLQKPALLALKDYEAQ
                     QAQGRLEPQFDPRPLGIENAELWVKIADRRKREG"
     gene            8204..9103
                     /gene="rapZ"
                     /locus_tag="P5537_00040"
     CDS             8204..9103
                     /gene="rapZ"
                     /locus_tag="P5537_00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004307996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HRV76459.1"
                     /translation="MQIVLISGLSGSGKSIALNVLEDAAYYVVDNLPAVLLPQLVAHL
                     HGAGWRRVAVAVDMRSGASIAALPQQVEALRATVRDLRFIFLEARDDALIARFSETRR
                     RHPMAVDGYTLEEAIQRERDALASVAELGHRIDTSDLHPNTLRAWVKDFIQMAPAEGM
                     TLMFESFGFKYGIPLDADLVFDVRCLPNPHYDPRLRPLTGRDQPVIDFLQGVPEVGRM
                     SQDIHDFVANWLPAYVRDNRSYLTVAIGCTGGQHRSVYIAEWLAERFRGQVEVIVRHR
                     STARRAADRAAGKVDANGDGNGQ"
     gene            9100..9489
                     /locus_tag="P5537_00045"
     CDS             9100..9489
                     /locus_tag="P5537_00045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HRV76460.1"
                     /translation="MRLELADWRGLLRPGDVLVALGGLLVCGYALLALWQGGVPDGAV
                     IRAGGKVMARVDLARERTIEVPGPLGVTLIEIRPGRARVAADPGPRQYCVRQGWLTQA
                     GAVAICAPNEVSLSLTGRAADYDSLNY"
     gene            9470..10024
                     /locus_tag="P5537_00050"
     CDS             9470..10024
                     /locus_tag="P5537_00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HRV76461.1"
                     /translation="MTPSTIELTPTAEDRRIARHAAAAIVLTVAEAAIPLPLPGVKPG
                     LANIVTLVVLARWGWREAVWVSLLRVLAGSLLLGQFLAPGFFLSLSGALASLVVLGLA
                     MHLPARWFGPVSHSILAAFAHIGAQLVVARLWLVPHDGVFYLTPVFALAAVVFGLLNG
                     LIAARLLRELQRVSPPQAGDPMER"
     gene            complement(10257..11159)
                     /locus_tag="P5537_00055"
     CDS             complement(10257..11159)
                     /locus_tag="P5537_00055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HRV76462.1"
                     /translation="MQATPSRAQHTADDERGQFDSLLPATRLDRRGFLAGVAAAGFAL
                     AVQPVHASTVISTASTGLAAGTAAIAVQGGELPVYYARPAAGDRLPVVLVVQEIFGVH
                     EHIRDVCRRLAHAGYLAIAPELFFRQGDPTTQPDIPAILQNIVSKVPDAQVMADLDAC
                     AAWSAGQGGDPARLAITGFCWGGRITWLYAGHKPSVKAGVAWYGRLVGAVSELTPQHP
                     LDVAGKLHAPVLGLYGGQDQGIPLADVEKMQAALSAAGGGSSIHVYPDAPHAFHADYR
                     PSYRKAEAEDGWKRALEHLAKALA"
     gene            complement(11332..11598)
                     /gene="infA"
                     /locus_tag="P5537_00060"
     CDS             complement(11332..11598)
                     /gene="infA"
                     /locus_tag="P5537_00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HRV76463.1"
                     /translation="MAKEELIEMHGSVTEVLPDGRYRVTLDNGHNLIAYSGGKMRKHH
                     IRIIAGDNVSLEMSPYDLSKGRITFRHLPGRPAGAAAAPPPRRR"
     gene            complement(11934..12401)
                     /locus_tag="P5537_00065"
     CDS             complement(11934..12401)
                     /locus_tag="P5537_00065"
                     /inference="COORDINATES: protein motif:HMM:NF001095.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HRV76464.1"
                     /translation="MHIWVDADACPVLVKDILFRASERTGHPVTLVANQFLRTPASPR
                     IRMIQVPGGFDEADRYIAEHAGAGDLVITADIPLAAAVVAKDAHALSPRGELYGRENI
                     RELLDLRNFMDTLRATGVDTGGPSAFSAADARSFANRLDVLLRRNTKPSTGKT"
     gene            complement(12473..12548)
                     /locus_tag="P5537_00070"
     tRNA            complement(12473..12548)
                     /locus_tag="P5537_00070"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12513..12515),aa:Lys,seq:ttt)
     gene            12720..13394
                     /locus_tag="P5537_00075"
     CDS             12720..13394
                     /locus_tag="P5537_00075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366545.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0031419 - cobalamin binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HRV76465.1"
                     /translation="MNGPHSSGPSTEAAFQPLVDALLVGDHKLAAAVAQHLIEQGCSR
                     EQVVTDGLEHAMGLLDDKCTVESFNLLEIMLVGRAVSAVVRVLYPDGYAPTEGRATFV
                     IATLEGDVHDLGKNIVRMVLAGKGFRVVDLGRDCPVDDLVGAAQREGAAAVLVSGLIS
                     PVVSQVRKLRPALRACGLAHVPVVAGGAALKQLRPEALDVDYVAENAFDGAHYLERHV
                     SGAPTT"
     gene            13391..14401
                     /locus_tag="P5537_00080"
     CDS             13391..14401
                     /locus_tag="P5537_00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase family protein"
                     /protein_id="HRV76466.1"
                     /translation="MNSLERILRATRLEPVDRTPLVPQLFGHAAVCAGLSLRDYLHDG
                     EALAHAQIRARERYRTDAVFAFLDFGVEAEALGAQLSFGDDRYPDVVGCVLGADDDPA
                     RLRLPEPASAGRMPVCLRALRTMRQRLGDSALVAGAVAGPMTASAQLYGIENALFLAI
                     DDPPRLAAALDFSTRLAIRYGLAQLDAGAHAVIVFDPAASPAVVPPGFFREFLAPRLG
                     RVLAALRGGGAAFTWLNIAGPTAGILDCYAHIGADVATFDYYLSAAEASRLLPRTCLA
                     GNLKSLDFLDAAPDVVKREARGLVAAFGGRGGFLLSSGCEIPPEAAAGNIAAMAAALN
                     ED"
     gene            14332..16014
                     /locus_tag="P5537_00085"
     CDS             14332..16014
                     /locus_tag="P5537_00085"
                     /inference="COORDINATES: protein motif:HMM:NF025925.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASKHA domain-containing protein"
                     /protein_id="HRV76467.1"
                     /translation="MRDSARGRRGQHRCHGGGAERGLSAMATLRVRAGGALHLLAYDP
                     DAGNSLRAILEPTDFRVRTACLGLGACGLCRVRVLAGEVGAPTAVERVQLEDALLAER
                     VRLACQCRPVGEVEIEVLSLAPPSSWHVPPGGLASIGTLRWEADPAPSHAVPRPLGVA
                     VDLGTSHISVALIDLIGARPLALRVGANPQRAHGADVMTRLVAAGDPDHARALASLAR
                     AAVGEALGEIARSEGIDLRRVRRVLVVGNTAMLSLLADRNHQRLLEPANWSLPIDCAP
                     LETASWGREWGLAPEASIEVVAPLAGFVGSDLLAGVVAERMPELRTPGLLIDFGTNSE
                     IALWSGDTLWVTATAGGPAFEASAGRDCIPAEAGAVVRVREGEGGALECDIIAGDEPR
                     GLCGSGLVDLLACLLRQRRLGPRGRFSDDSERVEFEVNGRMLGLGWREVDALQRAKAA
                     IGAGMKVLCGCAGVDPYALQRVLVAGLFGSHLDLDSAAAIGLLPRLPEGRVVLVGNTA
                     LAGACGLLLCADARRMLERVRACARFVNLGRMAAFDEAFLDQLFLQPMGSPP"
     gene            16011..17498
                     /locus_tag="P5537_00090"
     CDS             16011..17498
                     /locus_tag="P5537_00090"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD-GYP domain-containing protein"
                     /protein_id="HRV76468.1"
                     /translation="MSAVSSGPRTPVDAVVRTAQYLAGIVSYEGLWPQLGRLVRNFFG
                     ADVAAFIAREGEGGERCLHCEPDCPMLAAACAEATAMVFESGFLATEAVRIPEPHEVI
                     LLPIGRERQRTAYVLIAAHRGATALSRDTLDLYLALAGLIETTLDRIASQHRFLSMAD
                     NVPELLFQFVEHDGRWMFNYASGGARAALGLEAQALIADPALLFAGLDEAGGGRLLEA
                     LRASAAGRRVHLPLCWRAPDGGLRHLLLDAVAATGEQGRPVWDGALRDISEQVRLEEE
                     SRRNLVRLNKSMEDAIQAIATTIEKRDPYTAGHQRRVADLAARLAAALGMPDEQIHGI
                     RLTAAIHDIGKIHVPAEILSYPGPLPEIEFALIRTHPEVGYEILKNVDFPWPVAEMVL
                     QHHEHLDGSGYPRGLRGDAILLGARIITVADVVEAIALYRPYRPGLGVDTALAEIERS
                     RGARYDPAVVDACVELFRGQAYCFPETADPGRVFARAPAHRKPEG"
     gene            complement(17601..18707)
                     /locus_tag="P5537_00095"
     CDS             complement(17601..18707)
                     /locus_tag="P5537_00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeeE/YedE family protein"
                     /protein_id="HRV76469.1"
                     /translation="MDHALVSASTIVWLGFAIGAVFGASSQRTGFCTMGAVSDAVNIG
                     DWTRMRMWALAVAIAVLGTGVLQALGLFDPARTIYTGARLPWLSHVVGGLAFGVGMTL
                     ASGCAGKTLIRIGGGNLKSVVVFVFLAIGASMTLRGLTGVWRVELLDPVALQLPHAQT
                     LPAFLAAAGMDAGSALLAASALAGGGLLAWALASRDARRPEVLLGGAIVGLAVVAGWY
                     VTGHLGHIAEHPDTLEEVFLATNSGRAESLSFVAPQAFTLELLLLWSDANRQMSFGIA
                     SALGVIAGAAAMALATRSFRIESFRDPADLVRHIAGGLLMGFGGVTALGCTLGQGVSG
                     LSTLALGAALTTAAIIAGASATMKLQYWLLTRAP"
     gene            complement(18723..19424)
                     /gene="queC"
                     /locus_tag="P5537_00100"
     CDS             complement(18723..19424)
                     /gene="queC"
                     /locus_tag="P5537_00100"
                     /EC_number="6.3.4.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004379269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine synthase QueC"
                     /protein_id="HRV76470.1"
                     /translation="MTLLHTPPRAVVLLSGGLDSATCLAIARDMGFETYALSVAYGQR
                     HAAELVASKRVAQALGAREHRTASVELGQFGGSALTDPGIAVPLDQDNAGIPVTYVPA
                     RNTVMLSIALAWAEVLGANDIFVGVNAVDYSGYPDCRPAFIEAFERMARLATKVGVEG
                     AQLRIHAPLIELSKADIIRRGVALGVDYGLTVTCYQADDDGRACGRCEACRLRAAGFA
                     AAGVADPTPYQPPST"
     gene            complement(19507..20178)
                     /gene="queE"
                     /locus_tag="P5537_00105"
     CDS             complement(19507..20178)
                     /gene="queE"
                     /locus_tag="P5537_00105"
                     /EC_number="4.3.99.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="7-carboxy-7-deazaguanine synthase QueE"
                     /protein_id="HRV76471.1"
                     /translation="MSAVETAPAAAVRLRITEIFASLQGESTRVGLPTVFVRLTGCPL
                     RCSWCDTAYAFSGGETRTLDDILAEVAGHGLRHVCVTGGEPLAQKGCLALLAALCDAG
                     HDVSLETSGALDIAGVDPRVSRIVDLKAPGSGELARNRWENLALLNARDELKFVLADA
                     TDYDWARRQIAEHRLAERCTVLLSPVAGALDPADLAGWIVRDRLPVRFQLQLHKILWN
                     DARGR"
     gene            complement(20182..20973)
                     /gene="ybgF"
                     /locus_tag="P5537_00110"
     CDS             complement(20182..20973)
                     /gene="ybgF"
                     /locus_tag="P5537_00110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002925682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system protein YbgF"
                     /protein_id="HRV76472.1"
                     /translation="MKRLLPLAAALVLIPTAPAHAQLFGGDTEARNQIFQLRQEVQGQ
                     IETTSRGQLELAMQNEQMRAELARLRGQIELLTNEVETLKQRQKDFYVDLDARLRRFE
                     SGAAGNASAAPASGDAAPAAPAAAPAQAPTSVPAPASANTESADYQGALALLKNGKHK
                     DAQAAFERFVARYPNGNFTAGAHFWAGNSALQARDVASANRHFKTVIDKYPKENVAPD
                     AMLGLANSQQAMNDAAGARRTLQSLLERYPQSNAAQVARQRLNAR"
     gene            complement(20986..21498)
                     /gene="pal"
                     /locus_tag="P5537_00115"
     CDS             complement(20986..21498)
                     /gene="pal"
                     /locus_tag="P5537_00115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-associated lipoprotein Pal"
                     /protein_id="HRV76473.1"
                     /translation="MKKLVLPALLALTLAACSSTGPENGAASVTDRGTGVATVTAGSA
                     SGSGIAALTDPNNILSKRSVFFDFDSFVIKQEARALIEAHARFLVQNPQMNMLVQGNT
                     DERGSREYNLALGQKRADVVKQALMLLGAKESQIESVSLGEEKPRCEDRTENCYAENR
                     RGDMLYTGEF"
     gene            complement(21567..22862)
                     /gene="tolB"
                     /locus_tag="P5537_00120"
     CDS             complement(21567..22862)
                     /gene="tolB"
                     /locus_tag="P5537_00120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tol-Pal system beta propeller repeat protein
                     TolB"
                     /protein_id="HRV76474.1"
                     /translation="MIKTLHAFRPLHAFRLFLAGLLASLALSAHAQLSIEITGTGASR
                     FPVIIPIFENEGRLPQSVTDVVRADLERSGLFTLIDTGPLPMPESVAPDLAAVRGRGA
                     DAVLTGSLIPMSDGRYDVRFRLFDAQKQQELGAMSLPMSPAQNRLVGHRIADFVYEKL
                     TGLPGYFATRIAYVIKSGPNFELQIADADGMNAATALRSREPIISPSWSPDGQRLAYV
                     SFEQKKPIVYVHTLATGQRRVVANFKGSNSAPSWSPDGSQLAVVLTKDGLSQLYAIGA
                     DGSGVRRLAQSSGIDTEPFWGADGHIYFTSDRGGSPQIYRIPAGGGSAQRVSFEGNYN
                     VSPRLSFDGKLLAFITRNAGRFQVAVQDLATRQTTILTDSARDESPSFAPNGRMILYA
                     TDTGGRGVLSAVSTDGRIRQRLTVQAADVREPAWGPQIR"
     gene            complement(22903..>23367)
                     /locus_tag="P5537_00125"
     CDS             complement(22903..>23367)
                     /locus_tag="P5537_00125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015437877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy transducer TonB"
                     /protein_id="HRV76475.1"
                     /translation="PKPQAKPEPKPKPDSKPIDDYMAQRLAQETQRAEQARLSSLMAQ
                     EGARAAAAGPGRQGPPGGDIDKYRAAIAAKVRGNLLRPPGLSGNPEALFEVDQLPSGE
                     VLNVRLKRSSGVPALDEAIERAIRRSSPLPLPDNKSQFERTLELKFRPLADD"
     assembly_gap    23368..23467
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<23468..23964)
                     /locus_tag="P5537_00130"
     CDS             complement(<23468..23964)
                     /locus_tag="P5537_00130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004334796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB C-terminal domain-containing protein"
                     /protein_id="HRV76476.1"
                     /translation="MRDRPAPPRREPPGKWQSLGLTVAVHLGLFLFLFFGIRWQSPPP
                     AALEVGLASAPARSAPAAARPQPAPEPRPEPKPEPKPEPKPEPKPEPKPEPRPEPPKP
                     QAKPEIVAKAPEKKPEPPKPEPKPQPKPEPKPQPKPEPKPEPKPQPKPEPKPEPKPQA
                     KPEPKP"
     gene            complement(23961..24377)
                     /gene="tolR"
                     /locus_tag="P5537_00135"
     CDS             complement(23961..24377)
                     /gene="tolR"
                     /locus_tag="P5537_00135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0098567 - periplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0061024 - membrane organization [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein TolR"
                     /protein_id="HRV76477.1"
                     /translation="MRQRRLMNQINVVPYIDVMLVLLVIFMVTAPMIQQGTINVPSAG
                     AGTPPPQSEAIFIEVKADGAYALRASNSGTSRPVRREQLSTALKDAVAKNPEQPFLVA
                     ADSKLDYQKVIDVLETARDAGVRKISLVTQSTTSQK"
     gene            complement(24397..25065)
                     /gene="tolQ"
                     /locus_tag="P5537_00140"
     CDS             complement(24397..25065)
                     /gene="tolQ"
                     /locus_tag="P5537_00140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004371193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein TolQ"
                     /protein_id="HRV76478.1"
                     /translation="MTVTHDLSILSLISQASVLVQLVMALLAGLSLVSWYWIFRKAFQ
                     IRQARAQTDEFERDFWSGGDLNTLYESAGRHQSEGMERIFEAGYREFTKLRGKGHDHG
                     ATLDGARRAMRATYQREIDDLEAHLAFLASVGSVSPYIGLLGTVWGIMNSFRGLSSVG
                     AATLAQVAPGIAEALVATAIGLFAAIPAVVAYNRFAHDIDRLGIRFESFMEEFSNILQ
                     RNLR"
     gene            complement(25062..25514)
                     /gene="ybgC"
                     /locus_tag="P5537_00145"
     CDS             complement(25062..25514)
                     /gene="ybgC"
                     /locus_tag="P5537_00145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0047617 - acyl-CoA hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system-associated acyl-CoA thioesterase"
                     /protein_id="HRV76479.1"
                     /translation="MQPKTVSDAGGESLPASSRFSLPVRVYYEDTDAGGVVYYANYLK
                     FCERTRTEWLRALGVAQQALLDEQGLGFVVRSVHADYRAPARLDDALEVSARIVSRRR
                     ASLVFDHEVRRGGELLFTAQVLVACVDLRRMKPAALPDSLHALLESPA"
     gene            25674..26846
                     /locus_tag="P5537_00150"
     CDS             25674..26846
                     /locus_tag="P5537_00150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004371191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HRV76480.1"
                     /translation="MALPFFGRKPASAAPGAQRDARPGVEARAAQDDRPPPTELSALD
                     FTGTDHGRALARVAGQVEVRECGSGIGAAFEEAAVLYANGSDDDALAVLEAAVGSEGG
                     EGAWLMLLDLYRLRGERQRFESRVLDYATRFERSPPPWEDLSGMAGKAAGTELPLVNL
                     SGQLSAAAERQFAQLARIARRSGGVRIDVAKVHGVDDAGCGVWRGLLAGLAAERLQVT
                     LVNVRALADILSQAVHPGQAQARDTWLMLLELLQYAGDQARFEDLAVDYAVTFEESPP
                     SWEGRGTSPQATAVQVGEGPQADPDAFAFAGELCGAANDTLKRFAGFAAERREVRVDC
                     RGLRRIDFVCAGTLFNILATLQAQGKLVGLRDVNAMVAGLLRVMSVDKVAHVTLRH"
     gene            26890..27426
                     /gene="hslV"
                     /locus_tag="P5537_00155"
     CDS             26890..27426
                     /gene="hslV"
                     /locus_tag="P5537_00155"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011764158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004298 - threonine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0051603 - proteolysis involved in protein
                     catabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease subunit HslV"
                     /protein_id="HRV76481.1"
                     /translation="MEQYRGTTILSVRRGNRVALGGDGQVTLGNIVIKASARKVRTLY
                     NGQILAGFAGGTADAFTLFERFEAKLDKHQGNLLRSAVELAKDWRTDRMLRRLEAMLA
                     VADREHSLVITGNGDVLEPEQGIVAIGSGGAYAQSAARALVENTELDPKDIVSKALSI
                     AGDLCIYTNHHHTIEVLD"
     gene            27437..28774
                     /gene="hslU"
                     /locus_tag="P5537_00160"
     CDS             27437..28774
                     /gene="hslU"
                     /locus_tag="P5537_00160"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015437871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HRV76482.1"
                     /translation="MTQMTPPEIVSELDKHIVGQDKAKKAVAIALRNRWRRAQVDEPL
                     RSEITPKNILMIGPTGVGKTEIARRLARLANAPFIKIEATKFTEVGYVGRDVDTIIRD
                     LMEIAIKDGRERAMKSVRDRALDAAEDRVLDALLPPARPVGFNAEPEPAQDSSTRQKF
                     RKKLREGELDDKEIEIEVAAPSMQAEIFAPPGMEELTQQIQGMFQNLGGGKRKQRKLQ
                     IREALKLLADEEAARMINDEEVKLEAVRAVEQNGIVFLDEVDKIAARTDAHGADVSRQ
                     GVQRDLLPLVEGTTISTKYGMIKTDHILFIASGAFHLSKPSDLIPELQGRFPIRVELE
                     SLSVEDFERILTSTDACLVRQYEALLATDGVRLEFVAAGIRRLAEIAYQVNEKTENIG
                     ARRLYTVMEKLLEEVSFEAGRSSTVGTVVVDAAYVDSRLDMLAQREDLARYVL"
     gene            28892..29767
                     /locus_tag="P5537_00165"
     CDS             28892..29767
                     /locus_tag="P5537_00165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HRV76483.1"
                     /translation="MLIRIVSILFPLFAITALGYFVGRRMKPDLSHANKLNMDVFVPA
                     LVFGALVGKDFRLGEYLPLLFATVVIIVGSGVVGWLVARSAGIATKTLVPPMMFNNCG
                     NLGLPLAVLAFGESALAPAVVMFVVSNVIHFSYGAWLLDHHTRLTTVWRSPSILATIA
                     GLTVGFLGIEVWPPLLMSIEMVGDISIPLMLFALGVRLADSRISAVGFGLFGAVLRPV
                     VGMALAWGLLQVLELPPREQALVLVFGALPPAVLNYMFAERYDQEPDKVASMVLIGNV
                     AAVVFLPIALALVLD"
     gene            complement(29780..30550)
                     /locus_tag="P5537_00170"
     CDS             complement(29780..30550)
                     /locus_tag="P5537_00170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004371176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="slipin family protein"
                     /protein_id="HRV76484.1"
                     /translation="MIDLQFGLAPLFLLLIFLVVASIKILREYERGVIFLLGRFWKVK
                     GPGLVIVIPGIQQMVKVDLRVVTMDVPSQDVISRDNVSVKVNAIVFFRVIDPEKAIIQ
                     VENFLMATSQLAQTTLRAVLGKHELDEMLAERERLNLDVQQILDAQTDSWGIKVANVE
                     IKHIDLNESMVRAIARQAEAERERRAKVIHAEGEKQAAQSLLEAAQMLSREPAAMQLR
                     YLQTLTQVAGDKSSTLVFPVPVDLLGKLMQQDGGRARE"
     gene            complement(30547..32214)
                     /locus_tag="P5537_00175"
     CDS             complement(30547..32214)
                     /locus_tag="P5537_00175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004371159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HRV76485.1"
                     /translation="MPAPPPSALRTSTSAILALIGLVLLLLASQAGSSAAGALVLRVD
                     GAIGPASADYIHKGLTRAASTGAQLVVIELDTPGGLDTSMRSIIKDILASPVPVATFV
                     SPEGARAASAGTYILYASHIAAMAPATNLGAATPVAIGIGGAQPGRMPPLGDESAPAE
                     AAGSERDGSGSTSGASPPRARAQSPPASANRSPETTPEIRDDEANAPPSASDRPVIEA
                     PSSPAAAQRSAAPTDAMAAKSMSDATAYIRSLAQLRGRDVDFAERAVREAASLSAEEA
                     LAKGVIELIAIDTPSLLKRLDGREVAVLDGTRTLATAGIAIERMEPDWRNRILAALAN
                     PQVALILMMIGIYGLFFEFTSPGFGVPGVAGAISLLIALYAFQLLPVNWAGVLLLAVG
                     AGLMLAEAFLPSFGVLGVGGIIAFVVGGLFLMDADMPGFGIPIALIVGMALASAAVII
                     AIGSFAARSLRRPVVSGSEEMLGALGVVERATDDGDWWIAVHGEHWRARSAEALAPGG
                     RVRVAGIDGLTLMVTPIAAQSDAAAPAPGPDSAAPDTHHVTPGSTSS"
     gene            complement(32408..32809)
                     /locus_tag="P5537_00180"
     CDS             complement(32408..32809)
                     /locus_tag="P5537_00180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HRV76486.1"
                     /translation="MPAHPLTDPARTRLDKWLWAARFYKHRTAATEAVDGGKVKLNGI
                     TVKPARDVKPGDRLDITIGEETRTVLVCAIADRRGSATVAQTLYEETAESIAAREHAR
                     ELRKLAATPGADLHGRPTKRDRRRMDRFGGH"
     gene            complement(32935..33672)
                     /locus_tag="P5537_00185"
     CDS             complement(32935..33672)
                     /locus_tag="P5537_00185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="complement resistance protein TraT"
                     /protein_id="HRV76487.1"
                     /translation="MLKRIALITAAAFVLTGCAAAHVAISKRDLDVQTKMSDTVFLDP
                     VGADKRTIFLQIRNTSDKPDLAVNDEIAAALQAKGYTLLQDPDAAHYILQANILQVGK
                     SAPTAIEAAVNQGYGVAASGGLVLGAGAAYAGGASGRGIAAAGLIGSLAEGIAGAAVK
                     DVYFSMITDLQIKERIRGAGKAKVSSNHSLRQGNSGGSQVSYDEESSYKTYQTRIGSS
                     ANKVNLAFEEALPELKKGLITSIAGLF"
     gene            complement(33912..35192)
                     /gene="cysN"
                     /locus_tag="P5537_00190"
     CDS             complement(33912..35192)
                     /gene="cysN"
                     /locus_tag="P5537_00190"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysN"
                     /protein_id="HRV76488.1"
                     /translation="MSALENLPDIDNGLLRFLTCGSVDDGKSTLIGRLLFDTKTILAD
                     TLNAIEKTSAKRGMSAVDLSLLTDGLQAEREQGITIDVAYRYFSTGRRKYIIADAPGH
                     EQYTRNMVTAASTANLAIILIDARKGVLTQTRRHSYLASLVGIPHLLVAVNKMDLVDY
                     DQAVFERIKAEYLAFAARLGIKDVRFIPISALEGDMIVDRGERLAWYDGPTLLDILEN
                     APAAHTEQAEDFRFPVQFVCRPQDSANPELHDYRGFMGRVESGEIAVGDAVTVLPSGA
                     SSRVRKIELGGESLPRAIHEQSVTLLLEDEIDISRGDLIVKSAEAPEPVKQIDATVCW
                     LSETPLSPARTYLVRHTTREVKAKLAKIDYRLDVNTLEQEATNGLAMNDIARVTLKLA
                     QPIVADRYADNRATGAFIIIDESTNNTVGAGMIG"
     gene            complement(35266..36180)
                     /gene="cysD"
                     /locus_tag="P5537_00195"
     CDS             complement(35266..36180)
                     /gene="cysD"
                     /locus_tag="P5537_00195"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004334828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004781 - sulfate adenylyltransferase
                     (ATP) activity [Evidence IEA];
                     GO_process: GO:0019419 - sulfate reduction [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysD"
                     /protein_id="HRV76489.1"
                     /translation="MSTLTKQTLSHLDWLEAEAIHILREVAGQCANPVLLFSGGKDSI
                     CLLRLAEKAFRPGRFPFPLMHIDTGHNYKEVTDFRDKRAAELGERLIVRSVEDSMARG
                     TVVLKHAGESRNKHQSVTLLEAIEEFGFDACIGGARRDEEKARAKERIMSFRDEFGQW
                     DPKNQRPELWNLYNARSHKGENIRAFPISNWTELDVWQYIQREQLELPSIYFAHVRPV
                     VRKSGLLQPVTELTPAKDGDVVEDVLVRFRTVGDITCTAPVESDADTVEKILAETATT
                     TITERGATRMDDQTSEASMEQRKKEGYF"
     gene            complement(36188..36340)
                     /locus_tag="P5537_00200"
     CDS             complement(36188..36340)
                     /locus_tag="P5537_00200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76490.1"
                     /translation="MNGKHPAQATHSPAIGAGRRSLQQRLLALRAGLKAALRAFRTHP
                     IKHPQR"
     gene            complement(36344..37114)
                     /locus_tag="P5537_00205"
     CDS             complement(36344..37114)
                     /locus_tag="P5537_00205"
                     /EC_number="1.8.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0004604 - phosphoadenylyl-sulfate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0019379 - sulfate assimilation,
                     phosphoadenylyl sulfate reduction by
                     phosphoadenylyl-sulfate reductase (thioredoxin) [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenylyl-sulfate reductase"
                     /protein_id="HRV76491.1"
                     /translation="MNAAVSALRPAPANAATQPALTDALRATVGAKSAAALALLREAV
                     AEFGAHGELAFANSFGAEDMVLTDLILSHALPITVFSLDTGRLPAETYTLIGEVERRY
                     DTKLEIYFPDAGAVEQYVRGHGINAFYDSVELRKACCGVRKMEPLRRALAGRKAWITG
                     LRAAQSVTRSGLPVRETDTANGLEKLNPLSDWSETEVWAYIRINEVPYNALHDQFYPS
                     IGCAPCTRAIAVGEDVRAGRWWWENPETKECGLHVKAS"
     gene            complement(37111..37665)
                     /locus_tag="P5537_00210"
     CDS             complement(37111..37665)
                     /locus_tag="P5537_00210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF934 domain-containing protein"
                     /protein_id="HRV76492.1"
                     /translation="MSDKIIKNGRVVADNRLTVSLAEGEAPTDIAVPAGPVLVPLAVW
                     QARRDELLARARSGEVGVWLAAGEDVAALAEDLGLLQFVGLHFPKFTDGRSYSAATLL
                     RTRYGYRGELRAIGQVLRDQFNYMTRCGFDALQPQAERYTDEQLEAAIASLDDFTQPY
                     QRSVKDPLPLFRRVERGNGHEVQP"
     gene            complement(37658..39340)
                     /locus_tag="P5537_00215"
     CDS             complement(37658..39340)
                     /locus_tag="P5537_00215"
                     /EC_number="1.8.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004371391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0050311 - sulfite reductase (ferredoxin)
                     activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite/sulfite reductase"
                     /protein_id="HRV76493.1"
                     /translation="MYQYDEHDQRLLDQRVAQFRDQMRRHLAGELSADEFRPLRLQNG
                     LYIQRHAPMFRISVPYGHLASRQLRKLAHLARGYDRGYAHFTTRTNVQFNWPKLEDVP
                     EMLAELASVQMHANQTSGNCIRNITADPFAGVAADEVADPRPFAEILRQWATYNPEFA
                     FLPRKFKIAFNSAAEDRVVLRVYDIGLDLVRNADGELGFRVLVGGGLGRTPILGEEIK
                     PFLPWQHLISYCEAILRVYNRWGRRDNLWKARIKILVKALGPEAFAREVEEEWANSKD
                     GPNTITAAELARVSAHFAPPAYEALPTHDAAFDALLADNKAFATWVKRNVRAHRQPGY
                     AAVILSLKKTGTAPGDVTAEQMDLIADLADRFSFGEARMLHEQNVALADVRRADLFAL
                     WQAARAAGLATPNIGLLTDIICCPGGDFCSLANARSIPIADAIQRRFDDLDYQHDIGE
                     IDLNISGCMNSCGHHHVGHIGILGVDKNDQEWYQVSIGGTQGNGTTLGKVIGPSFALD
                     EVVGVIEKLLETYVELRFEDERFIDTVQRVGTEPFKARVYADRQPQRKAAHV"
     gene            complement(39409..40191)
                     /locus_tag="P5537_00220"
     CDS             complement(39409..40191)
                     /locus_tag="P5537_00220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HRV76494.1"
                     /translation="MDFAYTIAGFAVGAIVGLTGVGGGSLMTPLLVLMFGIHPSVAVG
                     TDLLYAATTKAGGTLAHGLKGTVDWKITRLLATGSIPAAAITLALIGHFAPGGIEGAA
                     HLIQVALGVALVLTAVALIFRKRIQAYAVARSGGRPADPARTARLTIITGAVLGVLVS
                     ISSVGAGALGVTALFFLYPAMPALRIVGSDIAHAVPLTAVAGIGHWFLGSVDWLLLGS
                     LLVGSLPGIWLGSHISTKVPDRILRPILAAMLVLVGAKLMAH"
     assembly_gap    40286..40385
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <40386..41111
                     /locus_tag="P5537_00225"
     CDS             <40386..41111
                     /locus_tag="P5537_00225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011764169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HRV76495.1"
                     /translation="VLRDLDNLQQVGDEFANEAVGRLSIATTHTQARYVLPDVVRRFM
                     QRYPQVKLELHQGNPRQVCEMVLDGSADIAIATEAIAEYDELVMLPCYQWNRCVVATP
                     RHPILQAAPLTLEEIARYPLITYDDAFTGRGQINKAFLGRGLKPKVVLTAIDSDVIKK
                     YVEMDLGIGILARMAYDPAEDRRLGMVDASHLFESSTTRIGLRKRAWLRAYVYAFIEG
                     FAPHLSRRMVEAALAGGGTDPGL"
     gene            complement(41155..42177)
                     /locus_tag="P5537_00230"
     CDS             complement(41155..42177)
                     /locus_tag="P5537_00230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HRV76496.1"
                     /translation="MIPQHNALQILRKPRIALLATGGTIAGTAGSATDTRDYTAGQLG
                     PEALLAAVPQLAELARIDATQVFSVDSKDMTPQHWLVLSRRVQRLMDDPAVDGIVITH
                     GTDTLEETACFLNITVAPTKPVVMTAAMRPATALSADGPLNLYQAVELACRPAAARAG
                     VLAVIGDRIVPAAALAKRHPSAVDAFAFEGALTTLASDAALQALAPSRYSRVVLPDEL
                     QHLPPVELLTVAAGSSPALASAVARALARAQLLNGAAGLVLALPGNASLPEAWRPALE
                     ELPNAVPVVLASRCGGGVRRHHENAPANWLDAGALDPLKARVRLIAGLGAGLRGARLR
                     RWFERA"
     gene            complement(42206..43957)
                     /locus_tag="P5537_00235"
     CDS             complement(42206..43957)
                     /locus_tag="P5537_00235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HRV76497.1"
                     /translation="MDSHDSFPFLKEIILFLALSGVLMPLLSRLKINPVLGFLSVGVL
                     LGPYGLASLAQAWPPLSWFTFARPDQVEFLAELGVIFLMFMIGLEMSVERLWSMRRLV
                     FGLGGLQVALSAGAVGALALWFGNGIEAAVILGVVLAFSSTAIVMQLLIQRHELGTPL
                     GQASFAILLFQDLAVVPLLVLISILGASSGEGSFAGLLGLAMLKGVLTVVGIYLIGRR
                     VVRPLFHQIAVDKQPDTFTALTLLTTLGVAALTWVAGLSMALGALLAGLIIAETEFRH
                     EVEITIEPFKGLLMGLFFMSVGMGIDLRALLAEPLWIPLSVVGLLAMKALIVFVLLRV
                     FGLSWGRSAEGGLLLGQGGEFAFIVIGMALALGLLERQVGQFMLIVVGVSMLAAPVVA
                     RLGQSLGDHIDRRIAPPAEEEDTELGELDGHVIIAGYGRVGQLVGQMLEEQGVSYIAI
                     ENNAQLIAHQRKAGVPLVFGDASRPELLRKLRIDQARAVVLTMDHTAAAINAVHGIRR
                     MVPMMRIIARARDEKHALLLREAGASVVVPETLESSLKLTGWVLETLGIPPDAALRLV
                     EQERERRIIALRDTGNA"
     gene            complement(43989..45863)
                     /locus_tag="P5537_00240"
     CDS             complement(43989..45863)
                     /locus_tag="P5537_00240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HRV76498.1"
                     /translation="MRRAPSAALPAPTTGERHDWQTLKSLFPFIWAYKGRVLFALACL
                     VAAKGANVSVPIIFKHLIDGLTITPEQAFIVVPAALLLAYGALRFSTSLLTELREVVF
                     ARVTQQAVREISLRVFRHLHALSLRFHLERQTGGLTRDIERGTRSIGSLISYTLYSIL
                     PTLIEIGMVIGILLANYDAVFALITLCALTIYIVFTVKVTNWRTALRREANELDSAAN
                     ARAIDSLINYETVKYFNNEEFEARRYDEQLQKWTKAQVTNQYSLSALNVGQAAIIAVA
                     VTAMMWQAAGRVASGEMTIGDIVLVNAFMIQLYIPLNFLGVLYREIRQSLTDIERMFG
                     LMHTHREIADAPDAHTLPTGPASVRFENVSFAYDAKRPILFDVDFDIPAGSTVAVVGH
                     SGSGKSTLARLLYRFYDVQGGAIRIDGHDLRSLTQDSLRAAIGIVPQDTVLFNDSLYY
                     NIHYGRPNASREEVEAATRAAQLEDFIRQLPEGYETRVGERGLKLSGGEKQRVAIARA
                     LLKNPAILIFDEATSALDSRTEKAIQAQIERAAEGRTALVIAHRLSTIMDADEIIVLD
                     KGRIVERGRHALLLAQGGAYAQMWLLQQQEETADSAAAGVRDDGADAKSFAAPAGGVA
                     "
     gene            45997..46680
                     /locus_tag="P5537_00245"
     CDS             45997..46680
                     /locus_tag="P5537_00245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HRV76499.1"
                     /translation="MPSPMTSTPPAPISDTRDRILDAAERLFVEHGFDGTSMRMITGA
                     ASANLAAVNYHFGGKDALVQEVFRRRLTALNQRRLATLDRLEAEAAGAPLKPSRIVEA
                     FFGTALELAADTEHGGRTFMRLLARTYNEPNAFVRQFLAEEYAEVMDRFLGALFRALP
                     EVPRTEILWRFHFMTGAMAFAIAGPGGLSELFEAAPDDGDPARLLPRLMSFLLGGLRA
                     PLPDGGPQA"
     gene            46735..49221
                     /locus_tag="P5537_00250"
     CDS             46735..49221
                     /locus_tag="P5537_00250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002925745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HRV76500.1"
                     /translation="MTWILLLSLPPLAGALAYGRAPLFAWLGAGLAWLLAMGIAAGWG
                     FWLTLLAMAVFAGVMSVFLIDSLRMKHLTSRIFGAFRATLPTMSQTEKDALEAGTVWW
                     EGELFAGRPDWKKLQAYPWPQLSAEERAFLDNETDELCRLTRDWECTQHGDMPAEVWQ
                     YIKAKGFLGMIIPKEYGGKGFSAYAHSQVVTKLSTRSSAPAVTVMVPNSLGPAELLLH
                     YGTPEQKQHYLPRLATGEEIPAFALTSPWAGSDAASIPDAGVVCKGEWQGEEVLGMRV
                     TFDKRYITLAPVCTVFGLAFHLYDPDRLLGGDEVLGITCALIPHDHPGVDIGRRHFPL
                     NAVWMNGPVRGKDVFVPLEFIIGGPKMAGQGWRMLMECLAAGRSISLPGSNTGMQKMV
                     ARAVGAYARVRYQFKTAIGRFEGVEEALTRIGANTYLSDAARVMTAGAIDLGEKPSVV
                     SAIVKYHVTERARQTVNDGMDVIGGKGICLGPQNFLGRAYQQIPVGITVEGANILTRS
                     LILFGQGAIRCHPYVLAEMHSAQKSDLKAFDKALWGHVGFTVSNAARALIMGLTGSHF
                     VKVPGDVAPETRRYYQQLTRFSAAFAFIADISMGTMGGALKRKEKLSARLGDILSLMY
                     LATATLKRFEAEGRHSADAPLMHWAIWDCMFRIQQAFEGVIANFPNKLFAFVLRRVVV
                     FPLGRPYVVPSDKLGHKVAALLLEPSPTRDRLTADVHLPTDIEDPVGALEAALAATLA
                     AEPVEAKLKDARRQGRFDPKNLASGDVDEIWRVALHAGVIDEREFALVERRNQLRNKV
                     IRVDDFPYDLDLKAAVQAMPERSPAQQVSA"
     gene            49218..50567
                     /locus_tag="P5537_00255"
     CDS             49218..50567
                     /locus_tag="P5537_00255"
                     /EC_number="2.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HRV76501.1"
                     /translation="MNASARHSAGKHAHPAGKKEASPANKPIYIVDGARTPFLKAKNA
                     PGPFTASDLATAAGSALLMRQPFAPDQLDEVILGCASPSPDEVNIGRVVALRLGCGNQ
                     VPGWTVMRNCASGMQAIDSAIANIQCGRSQLVLAGGVDALSHAPLLFSEKMVRWLAGW
                     YAARSTGDRLAMLKTFRLGHLAPVIGIMKGLTDPIVGQLMGQTAENLAWKFGITRADM
                     DAFAVESHRRVCAGQDAGHYANEIVPLIDRDGEVHAADDGVRRDSSMANLAKLKPFFD
                     RKYGRVTPGNSSQITDGAAWLVLATEEAVGRHGLKPLGRIVDSQWAALAPDQMGLGPV
                     HASMPILQRHGLAPNDLDAWELNEAFAAQVIACLRAFGDHDYCRTHFGVDAPGAPDAG
                     RLNVDGGAVALGHPVGASGARIVLHLLEVLRRKGGGRGLATICIGGGQGGAMLVETV"
     gene            50567..52606
                     /locus_tag="P5537_00260"
     CDS             50567..52606
                     /locus_tag="P5537_00260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-CoA dehydrogenase NAD-binding
                     domain-containing protein"
                     /protein_id="HRV76502.1"
                     /translation="MSANMQQDWKHWRLRREDTGLAWLELDKADASANVLSSEVMSEF
                     ARVLDALDAAPPKALVIASAKPAGFIAGADIEEFSRLDSVLAARMLVERGWLLFKRLA
                     ALSYPTLALIRGHCMGGGLELALACRHRLVVDEPGTKLALPEVMLGIVPGWGGMLRLP
                     ALIGPAAALDLMLTGKSVDAKKAKRLGLADDCVPARVMESAARIVALGGKPARQLPAK
                     ERATRWAMNGPLRRMVADKARAQAARKVSRANYPAPFAIVDIWEKYGGNALDVPASDP
                     SSLDSIFTSPTARNLVRVFHLQERLKAFGKDSDFAPRHVHVVGAGVMGGDIAAVCALR
                     GMTVTLQDQSVERIAPAIARATKLFERRHKGDQKQVRFTLDRLIPDPKGEGAASADLI
                     IEAIFENLEAKRSLFADLEARAKPDAVLATNTSSLRLEDIASALKAPARLVGIHFFNP
                     VPMLPLVEVVQGEATDAEVLRRATGFVRRIDKLPLPVQSAPGFLVNAVLGPYMLEALR
                     CVEEGVAPATVDAALIQFGMPMGPVELVDTVGLDIAVAAGKALAGEGVEPPARLLKLV
                     AEGKLGRKSGEGYYRWVEGKALKGADKEAAPEGLLARLLSQLPGRRRPDPAPPIPPGL
                     AERVLAPLLAATRRCVAQGVVADADLADAGVIFGTGFAPHTGGPLTYCRSKGKPD"
     gene            52827..54149
                     /locus_tag="P5537_00265"
     CDS             52827..54149
                     /locus_tag="P5537_00265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018988346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein transport protein"
                     /protein_id="HRV76503.1"
                     /translation="MQKTLIARVLPAALLALASGTASAAGFQLLEQNASGIGNAYAGS
                     AAVAENASTIFFNPAGMTQLQAREVSAGLSLVRPSFKFTNQGSIPAGPSSAQDAGDWA
                     ALPNAYLSWALNKDLYVGVGMGAPFGLVTEYNRDWVGSAHSIKFDIKTININPSIAWR
                     VNEKVSIGFGLNWQKMDAEYVRRAGAVTPLLGPLSPLSSTFVTLKADDASWGWNVGAL
                     FSVSEATKVGVSYRSKVKHELEGSLAFSGAAAQNPAFGGTTTDSSASADVELPDTFIA
                     SFAHKLDPRWELLGDVSWTGWSSIEKVDIVRTSGNLAGTPLATAQTLETDFQDTWRVA
                     LGANYQLNDAWKLKFGVAFDETPVKTAESRLTSLPDNDRIWFSFGGQWKPNKGSALDM
                     GVAYLYVDDTEINNGEAVDAAQRKVRGLVKGEYDSSVWIVGAQYSMSF"
     gene            54234..56615
                     /locus_tag="P5537_00270"
     CDS             54234..56615
                     /locus_tag="P5537_00270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004334866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
                     hydratase family protein"
                     /protein_id="HRV76504.1"
                     /translation="MSRLIIRKVAVLGAGVMGAQIAAHCANADVPVILFDLPAREGPA
                     NGVVDKALASMKKLDPAPFAAKDRAQYVEAANYGSDLARLGECDLVIEAIAEKMEWKL
                     DLYAKVAPHLKTGAIFASNTSGLSIEALAAGMPDDRRSQFCGIHFFNPPRYMPLVELI
                     PTAATDPALLDGLEAWLITRLGKSIVRAKDTPNFVANRVGVFSILAVLHHTARLGLAF
                     DEVDLLTGPRIGRPKSATFRTADVVGLDTLVHVLATMQATLPDDPWCAHFTTPEWLQA
                     LIAKGALGQKTKAGIYRKQGKQIQVLDLHLQDYRESGGEVLPEVEEILKLRNPVEKFA
                     QLAAHPHPQAQFLWSIFRDVFHYCAVHLAEIADNARDIDLAMRWGFGWAQGPFETWQA
                     AGWKAVAEMVRDDIAHGRAMSDVPLPAWVFERDGVHAPAGSYSAAENTLKPRAALPVY
                     QRQLYPDRVLGEAPDDRGETLWENAGVRLWRRADQDGRIGIVSITSKMHAVGEEVMDG
                     LLEAIARAERELDGLVIWQPAPFAVGANLQQVGEACRAGQFDLLEQMVAKFQRTSMTI
                     KHAQIPVVAAVQGMALGGGCEFVMHAAHRVFALESYVGLVEAGVGLIPAGGGSKEFAL
                     QAHNLAQRAAGGDVFPYIQNAFQTIAMATVAKSALEAVQLGFGRAGDDVVFNANEILF
                     AAIHRARALAESAWRPALVNPQVTVAGRNGIATCEMMLVNMAEGGFISAHDYRVAKAA
                     ATALCGGEVDTNRRVSERWILDVERAQFVELLKTEKTQQRIAHMLETGKPLRN"
     gene            56630..57829
                     /locus_tag="P5537_00275"
     CDS             56630..57829
                     /locus_tag="P5537_00275"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HRV76505.1"
                     /translation="MSKQIQDAYIVAAVRTPVAKRNGAFRAVRPDDMLATVLRGVLAK
                     VPSLDPSEIGDVVTGCAMPEAEQGMNVARIGLLLAGLPDRVPGITINRFCASGLQAVA
                     DAASRIRLGEADVMIAAGTESMSALPQIMGNKVSLNPEVFARAENVSIAYGMGLTAEK
                     VAQQWKVSREDQDAFAVESHRRACAAIAAGHFKDEILPYAVKSYAPGADGTVRITERL
                     VEHDEGPRPDAAADKLGKLRPVFAARGSVTAGNSSQMSDGAAAVLLMSEAAVRRYDVK
                     PIARFASFAVAGVPPEVMGIGPVEAIPRALTRAGVAMADLGWTELNEAFAAQALAVMR
                     QLEMDPAKVNPLGGAIALGHPLGATGAIRTATLMAAMQRDPGLRYGMISMCIGTGMGA
                     AGVFERV"
     gene            58167..59507
                     /locus_tag="P5537_00280"
     CDS             58167..59507
                     /locus_tag="P5537_00280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na(+)-translocating NADH-quinone reductase
                     subunit A"
                     /protein_id="HRV76506.1"
                     /translation="MIRIKRGLDLPITGAPEQRIEAGRPVRSVAVIGFDHHGMKPTMA
                     VQVGDRVKLGQVLFSDKKTPGVVYTAPGAGTVSAIHRGEQRVLQSVVIDLDGDDAIEF
                     RRCTDAEIDRLDDPTVRSNLIDSGLWTALRARPFGKVPAIDAKPHSIFVTAIDTHPLA
                     ADPTVVISEHKDDFARGVRVLARIAPVVVCHADGTQMPCSGLADVRTETFAGPHPAGL
                     AGTHIHFLDPVHAEKSVWSLNYQDTIAVGKLFATGRLWTERVVSIAGPMAAKPRLVRT
                     RLGASLDELTAGELKTGKKLRVISGSVFGGRTSRGACAFLGRYHLQVSCLEEGTEREM
                     LHYLRAGANKHSVMNLFISKLSSGKLFDFTTSTNGSPRAMVPIGNYEEVMPLDILPTQ
                     LLRALIVGDTEMAQKLGCLELDEEDLALCTYVCAGKYEYGPILRDNLTRIEKEG"
     gene            59510..60724
                     /locus_tag="P5537_00285"
     CDS             59510..60724
                     /locus_tag="P5537_00285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA];
                     GO_process: GO:0022904 - respiratory electron transport
                     chain [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:ubiquinone reductase (Na(+)-transporting)
                     subunit B"
                     /protein_id="HRV76507.1"
                     /translation="MSLRSWLDSIEHHFEKGGKYEKFYALYEAVDTALYKPPLVTRNT
                     AHVRDGLDLKRMMITVWLCTFPAMFFGMWNVGYQANTILAGSPELMAAQEGWRIALTG
                     ALAGLDPASLWANFVHGATYFLPIYLTTFIVGGFWEVLFASIRNHEVNEGFFVTSVLF
                     ALTLPPDTPLWQVALGISFGVVIAKEVFGGTGKNFLNPALAGRAFLYFAYPAEMSGDA
                     VWTAVDGYTGATMLSLGAAGGIEAVAGAGIDWMSAFLGTVHGSIGETSTLAILIGGAV
                     LLVMKIASWRIVSGVFLGMVASSLLFNAIGSDTNPMFAVPWHWHLVMGGFAFGMMFMA
                     TDPVSASMTNTGKWIFGAVVGVMTVLVRVVNPAFPEGIMLAILFGNLCAPLIDHFVVA
                     ANIKRRLARNVH"
     gene            60714..61499
                     /locus_tag="P5537_00290"
     CDS             60714..61499
                     /locus_tag="P5537_00290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na(+)-translocating NADH-quinone reductase
                     subunit C"
                     /protein_id="HRV76508.1"
                     /translation="MSTKESTTRTLMVALAVSLVSSVFVAGAAVSLKPVQIENRQLDK
                     QRSILSIAGLGGDGMSAREVKDLFASRIQARVVDLETGAYTDAHDPAVFDPLKAARDP
                     KLSDALAGEEDIALIKRRERFTTVYMVEKDGKLESLILPIRGYGLWSTLHGFMAVKGD
                     LNTVVGMGFYQHAETPGLGGEVDNPNWKGLWPGKQLFDEQGKPVIRIVKGGVDPASPE
                     AKHQVDALAGATLTSNGVDRLIQFWLGEQGFGPYLAKLRSKGV"
     gene            61502..62170
                     /locus_tag="P5537_00295"
     CDS             61502..62170
                     /locus_tag="P5537_00295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:ubiquinone reductase (Na(+)-transporting)
                     subunit D"
                     /protein_id="HRV76509.1"
                     /translation="MAKPTVKEVLFNPVFANNPIGLQILGICSALAVTSNLQTALVMS
                     LALTLVTGFSNLFISMIRNQIPSSIRMIVQMVIIASLVIVVDQILKAYAYGLSKQLSV
                     FVGLIITNCIVMGRAEAFAMQNPPVLSFWDGIGNGLGYSVVLLTLGVIRELFGAGKLF
                     GVEIIALAKDGGWYVPNGLLLLPPSAFFLIGLLIWALRTWRKEQVEKPAFRMAPQVVE
                     KEAY"
     gene            62172..62780
                     /gene="nqrE"
                     /locus_tag="P5537_00300"
     CDS             62172..62780
                     /gene="nqrE"
                     /locus_tag="P5537_00300"
                     /EC_number="7.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:ubiquinone reductase (Na(+)-transporting)
                     subunit E"
                     /protein_id="HRV76510.1"
                     /translation="MEHYLSLFVRAVFIENMALAFFLGMCTFIAISKKVETAIGLGIA
                     VIVVQTITVPANNLIYTYLLREGALAWAGLPDVDLSFLGLLSYIGVIAAIVQILEMLL
                     DKYVPSLYNALGVFLPLITVNCAIMAGSLFMVERDYNLAESTVYGIGSGASWALAIAL
                     LAGIREKLKYSDVPEGLQGLGITFITIGLMSLGFMSFSGVQL"
     gene            62796..64019
                     /gene="nqrF"
                     /locus_tag="P5537_00305"
     CDS             62796..64019
                     /gene="nqrF"
                     /locus_tag="P5537_00305"
                     /EC_number="7.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:ubiquinone reductase (Na(+)-transporting)
                     subunit F"
                     /protein_id="HRV76511.1"
                     /translation="MNTEIILGIGMFTAIVLALAVFIIAARSKLVSSGDVTIDINGEK
                     KITVPAGGKLLQTLAETGLFLPSACGGGGTCAQCKCIVKEGGGSMLPTEESHFTKRDA
                     KEGWRLSCQTPVKQDMKVEVPEEVFGVKRWECTVESNPNVATFIKELTLRLPEGEDVH
                     FRAGGYVQLECPPHVVNYKDFDIQDEYRGDWDKFNLWRYVSKVDETTIRAYSMANYPD
                     EKGVVKFNIRVASPPPGRDDIPPGKMSSWVFNLKKGDKVTVYGPFGEFFARETDHEMV
                     FVGGGAGMAPMRSHIFDQLKRLHSTRKISFWYGARSMREAFYVEEFDKLAAENPNFKW
                     HLALSDPLPEDNWTGYTGFIHNVLYENYLKDHPAPEDCEFYMCGPPMMNAAVIKTLLD
                     LGVERENIMLDDFGG"
     gene            complement(64180..64959)
                     /locus_tag="P5537_00310"
     CDS             complement(64180..64959)
                     /locus_tag="P5537_00310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HRV76512.1"
                     /translation="MELAPDTLLFWLKKLVAVLALPPVLPLLPIVLGLLALRRRPRLG
                     RALAWGGVALNLLLIMPPSVGWLVAQVEYPHTLDRARLREAQAIVVLGAGKRTHAPEF
                     GGETVNRLALERLRYAAALARETRLPLLVSGGAPAGDTPEANLMAALLRDEYGLPPRW
                     VETASRDTRENARFSAVHLQAAGVKRILLVTHAMHIDRARTEFEAAGLDVVPAPTAWL
                     GGGDTPAEAQALPLAPSQNTAYAAWFALHELFGQLAYRWSR"
     gene            65122..65715
                     /locus_tag="P5537_00315"
     CDS             65122..65715
                     /locus_tag="P5537_00315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2802 domain-containing protein"
                     /protein_id="HRV76513.1"
                     /translation="MREAMLWLAALLAAYATFEFLRALRLPREGAAGAFVAPQSAAAP
                     PATVVAARDDRDDEDDDFLAYAPLPSSASPAAGAAAAGPAPFPSDSAAAAEAAAAARF
                     ELELENSRLRQALQAQRDLVALQQSEIDRLVEDITALREELDAHAASVASSPEYSEAM
                     VLAAQGLNAEMIAERCGITLAEAELVLALGRDGEGRR"
     gene            65712..66365
                     /locus_tag="P5537_00320"
     CDS             65712..66365
                     /locus_tag="P5537_00320"
                     /inference="COORDINATES: protein motif:HMM:NF016895.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HRV76514.1"
                     /translation="MKLPRFPATRSSLPPGSPRRAALVRAAAALSAALVLLVLGLLDR
                     DRAAPPRPGGESVGAAPPGAPVATSPSLPPGATSPRAAGKLGSAAAAPGVETASGAVG
                     LAEVAAPTSSCPAPPPAPACPPPPAPTAQGDGILLPRAAAAPAGPGYLVQLGVFAAPD
                     NALRVYRQAAAAGQPAHIQSRVVLGPFADRESAERARKRLQAAGAGPGVLIPPQRPR"
     gene            66440..66877
                     /gene="fliW"
                     /locus_tag="P5537_00325"
     CDS             66440..66877
                     /gene="fliW"
                     /locus_tag="P5537_00325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliW"
                     /protein_id="HRV76515.1"
                     /translation="MQIKSPLFGSAEISEDKIIEFPRGLPGFEHCRRFTLLHEEGREA
                     HVFVLQSVDEPDVAFSVTAPERLGVHLEFPLDDQEVALLRLHAPEDAAVAVIVRKDDG
                     EGPAGTGLRANFMAPLVINTGARVGLQKVIDRLGCEITLRAGG"
     gene            66959..67339
                     /locus_tag="P5537_00330"
     CDS             66959..67339
                     /locus_tag="P5537_00330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002925771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HRV76516.1"
                     /translation="MARQIISTPNAPAAIGPYSQAVKVGNQVFLSGQIGLDPATMEMV
                     EGVEAQARRVFDNLAAVAEAAGGSFADVVKITIYLTDLANFGVVNEIMKSCFAEPYPA
                     RATVGVRELPRGALVEADLVLVIE"
     gene            67510..69555
                     /gene="recG"
                     /locus_tag="P5537_00335"
     CDS             67510..69555
                     /gene="recG"
                     /locus_tag="P5537_00335"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011764212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HRV76517.1"
                     /translation="MQPPRGWPGVGAQLAGRLAKLDLRAPRDLLLHLPLRYEDETRLT
                     PIAQVRPGFPAQVEGEVTSAEVVLRPRRQLVARISDGSGTLVGRWLNFYPSQQKQLAP
                     GARVRLFGEARGGFFGLEMVHPRLRAVAPGDALPDALTPVYPTTAGVGQLTLRKLVAQ
                     ALHSESLDELLPADWLRRLGLPGFAEALRALHHPAPDADPFALEQREHPAWQRMKFEE
                     LLVQQLSLRRAWLARRAQAAVALPARGLLTAALLDSLPFRPTGAQARVGAEIAADLAA
                     PHPMQRLLQGDVGSGKTLVAALAMLQAAENGWQAAMMAPTEILAEQHWKKLSAWLEPL
                     GIGVAWLSGSRKKRARAAELARLASGEVLLAVGTHALIEDPVTLPRLALAVVDEQHRF
                     GVRQRLALREKGEGGRRPHMLMMSATPIPRTLAMTHYADLDVSVLDELPPGRTPIRTR
                     LVSDVRRDEVVARVRAACLEGRQAYWVCPLIEESEALQLQTAQDTFATLVEALPELRV
                     GLVHGRLKNEEKSATMAAFSAGEFDLLVATTVIEVGVDVPNASLMVIEHAERFGLAQL
                     HQLRGRVGRGTAESVCILIYAQPLSQTGRERLKVIYENTDGFAIAREDLRIRGPGEFV
                     GARQSGVPLLRYADLEIDAALIEPARELAEHLLAHDPASANALMRRWLGGREALLRA"
     gene            69777..70304
                     /locus_tag="P5537_00340"
     CDS             69777..70304
                     /locus_tag="P5537_00340"
                     /EC_number="4.1.3.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008813 - chorismate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate lyase"
                     /protein_id="HRV76518.1"
                     /translation="MPIRREPASLSQGSSPAGSTARIRARCAGFEVRVLCQRLARVRR
                     DEALLLGLRAGELAWLREVLLVADSRPVVFARSLLPRRNLRGAWNLFHGIGARPLGAA
                     LFSDPAIARLPLACRRLDGRDARYHRAAAALARQSPAPALPAALWARRSVFLLRGRAL
                     MVSEAFLPAILELRK"
     gene            70301..71179
                     /gene="ubiA"
                     /locus_tag="P5537_00345"
     CDS             70301..71179
                     /gene="ubiA"
                     /locus_tag="P5537_00345"
                     /EC_number="2.5.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008412 - 4-hydroxybenzoate
                     octaprenyltransferase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybenzoate octaprenyltransferase"
                     /protein_id="HRV76519.1"
                     /translation="MTPAMSLSDKLPHYARLMRIDKPIGTLLLLWPTLWALWIAAEGW
                     PPLYILAIFIAGTFLMRSAGCVINDYADRDFDGHVERTRNRPLATGVVSPGEALALAA
                     VLSAAAFVLVLPLNTLTILLSVPALLLAGSYPFTKRFFAIPQAYLGIAFGFGIPMAFA
                     AVTGTVPATGWLMLLANIFWAVAYDTEYAMVDRPDDLKIGIKTSAITFGRHDVLAVML
                     CYAAAFALLAVVGVLAGLGFAWYLGLVVACAIAGYHYTLIRARERADCFKAFRHNNWV
                     GGAIFAGLFIDLLLRA"
     gene            71212..72045
                     /gene="pyrF"
                     /locus_tag="P5537_00350"
     CDS             71212..72045
                     /gene="pyrF"
                     /locus_tag="P5537_00350"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002925782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HRV76520.1"
                     /translation="MHFMTALRAAWQQRDSLLCVGLDPDPAKFPAHLQGRPDAILAFC
                     TQIVDATADLVCCFKPQIAYFAAHRAEDQLEALIEHIHAAHPDTPVILDAKRGDIGST
                     AEQYAIEAFERFKADAITVNPYMGRDSVDPYLAWPDKGVILLCRTSNPGGSDLQFLEV
                     DTPHGRMKLYEHVARTVADDWNASGNCALVVGATFPAEIARVRELVGDMPLLVPGIGA
                     QGGDIAATLAAGRTANGSGLMINSSRAVLYAGKGEDFAQAARRVAQETRDAVNVHRVS
                     K"
     gene            72317..74164
                     /locus_tag="P5537_00355"
     CDS             72317..74164
                     /locus_tag="P5537_00355"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76521.1"
                     /translation="MTLSLTDLGAGTTSNSLSFGQNLKATALVLDKTGKPVPNAIVSF
                     GASPDSLVALIPDVGTALTGADGKASIQLAQQSLTSAGAGTLTARSEVDGVETADSEN
                     FSVSPASVSLEQMQVGRSPLSAYGTTSVSVDVKGVPNTVPVTVAFTSNCATLGKANLT
                     QSVISLNGKSIANYEDKGCARTDTITATVAGTSVSTSTSLQVEAPGVSSIRFMSASPE
                     TIVLKGTGSADFPEVSQVSFKVVDSNGAPIQNALVTFSLSTATGGILLESTAVSGPSD
                     TVTKSTGADGLVQVTVQSGTIPTPVWVIASTTDSGGKAITTQSVKLSISTGRPAQDRM
                     SLAVESHNIEGLDYDGQAVKVTARLSDRLGNPVPDGTAVNFIASGAQIGATCQTEVGA
                     CSVDFVSGNPRLNGRIAILAYALGEESFLDLNSDNLYALAVEGPNFTDLGNAFLDRDE
                     NGQFDAGEQSVPYGSGSSGCVNRLSTSPGAPSVSGTCDGVWGPAHVRQENVIVLSGSD
                     AFLSRTRFSMAGECSYTVDDFRLFDRNNNPMPEGSKIEAIVEGTEFTSATVTPNIVRD
                     TAAPGGTYHSLTLKRKETSGCDTAPDRTLPLEITTPRGNVTPITLTITK"
     gene            74305..75795
                     /gene="ubiD"
                     /locus_tag="P5537_00360"
     CDS             74305..75795
                     /gene="ubiD"
                     /locus_tag="P5537_00360"
                     /EC_number="4.1.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-polyprenylbenzoate decarboxylase"
                     /protein_id="HRV76522.1"
                     /translation="MNYSDLRDFLTQLEARGELRRIKTPVDTYLEMTEIADRVLRAGG
                     PALLFERPVTKGVPQAIPVLANLFGTPQRVAMGMGEDVTDGNWSAPLREVGKLLAYLK
                     EPEPPKGLKDAWDKLPVLKQVLNMAPKEVRSAPCQQVVWSGDEVDLAKLPIQHCWPGD
                     AAPLITWGLVVTRGPHKKRQNLGIYRQQVIGRNRVIMRWLAHRGGAIDFLEHQRAHPG
                     EPFPVSVVLGCDPATILGAVTPVPDSLSEYQFAGLLRGAKTELVKCLGNDLQVPASAE
                     IVLEGVILPNETAMEGPYGDHTGYYNEQAEFPVFTVERITMRRDPIYHSTYTGKPPDE
                     PAMLGVALNEVFVPLLQKQFTEIVDFYLPPEGCSYRLAVVSIRKQYPGHAKRVMFGIW
                     SFLRQFMYTKFIIVVDEDVNIRDWKEVIWALTTRMDATRDTTLVDNTPIDYLDFASPV
                     AGLGSKMGLDATNKWPGETSREWGTPIVMDAAVKAKVDAMWGELGL"
     gene            75917..76330
                     /locus_tag="P5537_00365"
     CDS             75917..76330
                     /locus_tag="P5537_00365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76523.1"
                     /translation="MSNPYPAPIGAGQPSENMVTVTHLVYALHAFAVFSAVVGSATII
                     FSFVASLPSIAAVILNYWNQNAVRGTWLESHFRWQIRTFWFAVLWIAVSALMVVTIIG
                     VPFALALLLIAGLWILYRIVRGWWNLMQRQTMPMA"
     gene            complement(76584..78017)
                     /gene="dacB"
                     /locus_tag="P5537_00370"
     CDS             complement(76584..78017)
                     /gene="dacB"
                     /locus_tag="P5537_00370"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004175 - endopeptidase activity [Evidence
                     IEA];
                     GO_function: GO:0009002 - serine-type D-Ala-D-Ala
                     carboxypeptidase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine
                     carboxypeptidase/D-alanyl-D-alanine-endopeptidase"
                     /protein_id="HRV76524.1"
                     /translation="MKNLSLCVIFVTSLLLVGPGHADGNALPPGVRLALDSAQIPVEA
                     IAVWARPVDRPAPTLAINAGAAMNPASVMKLVTAFAALERLGPAHTWTTRIAGDGPLR
                     AGVLEGNLYLVGGADPVLGYDRLWKMLRRLRALGVERIAGDIVLDASALRLPPHDPDA
                     FDGRGLRPYNSGPHGLLLHYNTLLLGLHPGKVANAPVTLAAEPPLAGLVIDNRILTSD
                     APCGTWYRDLQATLEPGRRLVLSGSLPAACGPRTWSAAPLPPAEFGSALVAALWSEVG
                     GRLGGTVREGRLAASAEELFGDDSDPLADVVRDMNKWSSNVIARQLLATLGRVSLRED
                     ATEDMVAAGARAAAATLAAAGIDTDGLVIENGSGLSRNERIRADSLGALLLAVWQRPW
                     MPEFIAALPVAGLDGTARRRLGDSPARGQAHIKTGTLNGVRAMAGYLLDRKGQRHVVV
                     MMVNHPDAAASAAAQDALLEWLWSGGE"
     gene            78161..78511
                     /locus_tag="P5537_00375"
     CDS             78161..78511
                     /locus_tag="P5537_00375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76525.1"
                     /translation="MSGFGHYARTADELEREILKRGIAIGIDWDDPSRMRDLARRALS
                     CTPACMMKLLRSPVRQDKLTGELFALSELMLQNMRESAEIGFETHGGPAWKAFGRALN
                     EEFDAGVRPPEAGA"
     gene            complement(78594..79865)
                     /gene="lysA"
                     /locus_tag="P5537_00380"
     CDS             complement(78594..79865)
                     /gene="lysA"
                     /locus_tag="P5537_00380"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011237098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HRV76526.1"
                     /translation="MNAPAARWPAPTLSARDGALWLEDLPLAEIAARFGTPTYVYSRA
                     ALEAAFTAWKDALAGRPALVCYAVKANSNLGILSVFARLGAGFDIVSGGELARVLAAG
                     GRADKVVFSGVGKTRAEMRQALQAGIRCFNVESAAELEHLDAVAGELGVSAPVSLRVN
                     PDVDPKTHPYISTGLKGNKFGVAFAEAPAIYRRAAALRNLRITGVACHIGSQLLDRAP
                     IAEAAYKVRDLVERLAADGIALEHIDLGGGLGIRYRDETPPPVADYLAPLLEVFAGRE
                     EELCFEPGRSLVGNAGLLLTRIEYLKPGETKNFAIVDAAMNDLARPALYDAWHDVVEV
                     APRTLAPTTYDVVGPICESGDFLARERDLAVTEGDLLAILSAGAYGMTMASNYNTRPR
                     AAEILVDGASAHVVRERETVEELFARERVPA"
     gene            complement(79862..80050)
                     /locus_tag="P5537_00385"
     CDS             complement(79862..80050)
                     /locus_tag="P5537_00385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HRV76527.1"
                     /translation="MKRATMRARLPAIALASALLSACGIKGPLYLPAPGTTTSPPAGA
                     DHSKPVVPKDLIKESPLE"
     assembly_gap    80058..80157
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            80225..80551
                     /gene="cyaY"
                     /locus_tag="P5537_00390"
     CDS             80225..80551
                     /gene="cyaY"
                     /locus_tag="P5537_00390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron donor protein CyaY"
                     /protein_id="HRV76528.1"
                     /translation="MEESAFNALAEAELARIETALEDCGAELDVEPKPGGILELEFDN
                     GSKMIINRHTAAREIWVAAKSGGFHFRPQDGVWVNTRDGRELWAMLAALVGEQSGEAV
                     RLVRRD"
     gene            complement(80763..83186)
                     /locus_tag="P5537_00395"
     CDS             complement(80763..83186)
                     /locus_tag="P5537_00395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HRV76529.1"
                     /translation="MRWVLYPIAALFALAILGIATLAAMAFFAWPKLPALDTLTDYRP
                     RVPLRVYTADGHLIGEFGEERRDVVRIAEVPSHLKHAILAAEDERFYEHRGIDPFGLA
                     RAALANLSSGGRGQGASTITMQVARNFFLSREKTYNRKLYEILLALKIEQNLSKDQIL
                     ELYINQIFLGQRAYGFAAAARAYYGKTLDELTLPEAAMLAGLPKAPSAFNPIVNPARA
                     AVRQQYVLRRMLEAGFIAPQQYEEALAFATPKQSQRDIAAARRVPDIVVPGDYVAEMA
                     RQIAVEQFGEQAYELGLRIVTTVTRKDQEAAYAALRRGVLDYDRRHGYRGPEAFVDLP
                     SGQVAGERLDEALGEFSDHDDLLTALVLKAGPKEVLVYRRGQEIRITGKGLSFVAPML
                     SEKAPQARRVRRGAIVRVRNTGKDAWELTQLPEVQAALLAIDSRSGAVRALIGGFDFN
                     RNKFNHVTQAVRQPGSSFKPFIFSAALDREFGPGSVLEDNPLYYPAGVTGSKAWEPKN
                     YDGRYSGPMTLRDGLARSKNMVSIRLLEKITPEYARDYLARFGFDPAQNPPYLTMALG
                     AGAATPWQMAAGYAVFANGGYRVEPFVIKEMYDGSGRLIARTDPPVAGQSAPRVIDAR
                     NAWLMDSMMRDVVQRGTATRARSLKREDLAGKTGTTNDYVDAWFCGYHPDLVAVSWVG
                     HSQPRNLGKGETGGAAALPIWINYMASALEGTPQVELPRPDGLRQVQNGLGTQQDWQY
                     AEYAPPTPPPVPDWLREMFAGDSAPAMEAEAEAIPPGPAPLILPPPGPARAQAPAPVE
                     ERRPTPIRP"
     gene            83374..84450
                     /locus_tag="P5537_00400"
     CDS             83374..84450
                     /locus_tag="P5537_00400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HRV76530.1"
                     /translation="MIDLPFLSPSARQLVGLDISSSSVKLVELSGGEKDAYKVERYAV
                     ETLPRDAVVDGNIANLDAVSESVRRALRRFGTGVRNVALALPSSSVITKKIILPDGLR
                     ETEMEFAVEAEANQYIPFALEEVNLDFQRIGPAPGSPGDVEVLIAASRKDKVEDRVAV
                     AEAAGLKAVIVDVESLATESALELVCRQLPRGGADQVIALVDIGASVMNVTMFRNGHS
                     IYSREQAFGGSQLTQDIARQYGMSFEEAESAKRAGSLPDSYPRDLMRPFMDSLALEVS
                     RALQFFFTSTPFNQVDHVVLAGGCSVLPGLGDVVAARTQVDTLIANPFAGMTLSGKVR
                     PKALLADAPALMVACGLALRRFDA"
     gene            84447..85052
                     /locus_tag="P5537_00405"
     CDS             84447..85052
                     /locus_tag="P5537_00405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HRV76531.1"
                     /translation="MIRINLLPHRIAKRRQRRQQFYALAAGMVLLGALIGFGVHMIYA
                     GHIERQEARNAFLKQEIARVDRDIAEIRRLREQIDAMLARKQVIESLQGTRAETVHLF
                     NELAQRLPDGVYLKSTKQTGRQVRVVGLAQSNARVSHFMRNVEASAFLEQPRLIEAKA
                     VTQDNRRLSEFTLDIAIRPPVEAEPEAAASAPKAVAKGAQK"
     gene            85049..85732
                     /locus_tag="P5537_00410"
     CDS             85049..85732
                     /locus_tag="P5537_00410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HRV76532.1"
                     /translation="MRLDLAALREGIDFRRLAEDFKGLDPQDPGMWPTAPRIVVAVLL
                     LVLTVAGFWWFDWQDQVKTLEAREAEEVQLRESWVVKKRQAVNLEEHRRQLAEIDRQF
                     GALLKQLPNRAEMDSLLSDINQAGLGRGLQFELFKPGTDVIKEFYAEMPIDVRVTGVY
                     HDLGEFVADLASMPRMVTLNDVGIDADKDGRLKLQAKAVTYRYLDEEELAQQRKAAQA
                     AQAAKQGKK"
     gene            85729..86253
                     /locus_tag="P5537_00415"
     CDS             85729..86253
                     /locus_tag="P5537_00415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilP"
                     /protein_id="HRV76533.1"
                     /translation="MMNRAAMIGACVLLAGCTGGSQDDLKTWMDEQAKTMRGAVRPLP
                     ELRQVPVVAYAGTQGDDPFRIGRMEPERRASASALRPDLDRRREPLEAFPLESLQMVG
                     VLMQGNNTHALIKAGTVLHQVKVGNYMGQNFGVITQITENEIKLRELVEDVYGDWVEK
                     VSDLKLQERGEAGK"
     gene            86250..88403
                     /locus_tag="P5537_00420"
     CDS             86250..88403
                     /locus_tag="P5537_00420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus secretin PilQ"
                     /protein_id="HRV76534.1"
                     /translation="MRHRIGVLLIAAAFAGLAPAPAVLAQDASQTQSFSNQIEGLEVA
                     EQGGAIYVRLTLREPLASPPPSFSVANPARIAFDFPGTANALGRNVQAIDQGDLRSAN
                     IVQAGDRTRLVLNLTRMSPYEARVQGRDLIIALSPAAARAAQGSVVSEAAANFAEPRA
                     AAAAAGGLAVRDINFRRGTAGEGRVVVDLSSPDTGIDIRQQGGNLVIDFLQTALPEHL
                     RRRSDVTDFATPVTSMTAQQVGDRVRLTVTPNGLWEHNAYQSDNRFVLEVRRVAEDPT
                     KLGGGRSDYKGEKLSLNFQNVDVRSVLQVIADFTDFNIITSDSVQGNLTLRLKDVPWD
                     QALDIILQAKGLDMRKNGNVIWIAPGDELAAREKLQLEAKAQISDLEPLQTESFQINY
                     HKAKEIFDFLKSKDQTMLSKRGSVVVDERSNKVFVTDVATRLQALRRLVQEIDVAPRQ
                     VLIEARIVEASKTFARDLGVRLGVGGAFGRIVGYTEDGAPVRRSTLGGGLGATRTMAG
                     QVAGVVDANPAGLNLNLPADVSNPGLLSMVLWNNNATRFLNLELSALEVDGRGRVISS
                     PRVLTANQVEASIEQGTEIPYQEASSSGATSVSFKKAVLSLKVKPQITPDGRLQLSIE
                     VNKDRPLYEQTLLGVPPIETKNVKSEVLIENGGTVVIGGIYEEEESTGEDKVPLLGDV
                     PVLGHLFKSQSRVSSRKELLVFITPRIVSDALTLR"
     gene            88491..89021
                     /locus_tag="P5537_00425"
     CDS             88491..89021
                     /locus_tag="P5537_00425"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HRV76535.1"
                     /translation="MSCLILIGMMGAGKTTVGKELARRRKMRFADCDQAIVARTGVSI
                     PTIFELEGEAGFRRRETQMIDELTREPDLVLATGGGVVTTPLNRELMRERGIVIYLDV
                     PTQVLFERTRHDRNRPLLQVENPRQRIEELYRARDPLYRETAHIILEGGRGNPGNMVR
                     QIEEALARYKADTCRP"
     gene            89009..90091
                     /gene="aroB"
                     /locus_tag="P5537_00430"
     CDS             89009..90091
                     /gene="aroB"
                     /locus_tag="P5537_00430"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002925800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HRV76536.1"
                     /translation="MQTLNVALGERAYPIHIGRGLLGRADLILPHLKTKRVAIVTNAV
                     VGPLYLERLRAGLEAAGVRNAAVVLPDGEAHKDWETLNRIFDMLLAEHCERSTTLVAL
                     GGGVVGDMGGFAAACYQRGMPFIQVPTTLLSQVDSSVGGKTAINHPLGKNMIGAFYQP
                     RLVLADIDTLDTLPDRELSAGLAEVIKYGLIRDPEFLVWLEANLDRLLARDTEALAWA
                     IERSCRNKAEVVAADETEQGERALLNLGHTFGHAIETGLGYGEWLHGEAVAAGTMMAA
                     ELSRRLGWIDAGAVARIEALFERARLPVWGPRMGVERYVELMSHDKKVEAGKLRLVLL
                     REIGCAVMHGEAPASEIAAAIEARCR"
     gene            90202..91326
                     /locus_tag="P5537_00435"
     CDS             90202..91326
                     /locus_tag="P5537_00435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016793 - triphosphoric monoester
                     hydrolase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyguanosinetriphosphate triphosphohydrolase"
                     /protein_id="HRV76537.1"
                     /translation="MLQLAPYAVTEAASRGRVHDEPAPVARGQFQRDRDRIVHSTAFR
                     RLEYKTQVFVNHEGDLFRTRLTHSIEVAQLTRGIARELGLNEDLAEAIALAHDLGHTP
                     FGHAGQEALNACMKDYGGFEHNLQSLRTVDLLEDRYAGFDGLNLMFETREGILKHCSR
                     VNAERLGELGQRFLDGTQPSLEAQLANLADEIAYNNHDVDDGLRSGLITLEQLDEVPI
                     FAVQRREAEARWPGLSGRKLINETVRRMIHLMVIDLIEQTRANIAAEGVATLADVHAA
                     PRLVAYSDALLPPLRELKVFLRDKLYRHYQVLRMTNKARRIVGDLFTAFTDDPHILPP
                     QYQAMAREDKPRAIADYIAGMTDRYAMKEHRRLFAVGEIY"
BASE COUNT        13709 a        30774 c        32317 g        14477 t
ORIGIN      
        1 cgatgttcgc cggcgggctg tggatgctgt tgcaggagcc gctgtggttc ctggtggcgc
       61 tggtggtgtt cgtggtgctg gcggtggcgc tgatcgtggt gctgtggcgc ttcctgcgtc
      121 gggtgttccg cccgcgcttg cggccggcgc atcccgagct gcccgcgccg tgatggctgc
      181 aaggacagat ttctgaattc cgacaagaag ctggagacga catgttcgac aagatcctga
      241 ttgccaatcg tggagagatc gcctgcaggg tgatcaagac cgcccgccgc atgggcatca
      301 agaccgtcgc ggtgtattcc gaggccgacg ccaacgcccg ccacgtgcgc ctggccgacg
      361 aggcggtgct gatcggcccg gcggcggcgc gcgagagcta cctggtgatc gacaagatca
      421 tcgccgcggc caaggccacc ggtgcccagg ccatccaccc cggctacggc ttcctgtccg
      481 agaacgagga cttctgccac gcctgcgagc gcgaaggcat cgtcttcatc ggcccgccgg
      541 tgtcggcgat ccgcgccatg ggctcgaagt ccgaggccaa gaagctgatg gaggcggccg
      601 gcgtgccgct gacccccggc tatcacggcg acgaccagga gccctcgtac ctgcaccagc
      661 aggccgacgc catcggctac ccggtgctga tcaaggccgc ggctggcggc ggcggcaagg
      721 gcatgcgcct ggtcgagaag tccgcggact tcatcgacct gctcgcctcc tgcaagcgcg
      781 aggccagctc cagcttcggc gacgaccacg tgctggtcga gaagtacatc accaagccgc
      841 gccacatcga gatccaggtc ttcggcgaca cccacggcaa cgtggtgtac ctgttcgagc
      901 gcgactgctc ggtgcagcgc cgccaccaga aggtgctgga agaggcgccc gcgcccggca
      961 tgacgctcga gcgccgcgcg gcgatgggca aggcagcggt cgatgccgcc aaggcggtgg
     1021 gctacgtcgg cgccggcacg gtggagttca tcgccaacca ggacggctcc ttctacttca
     1081 tggagatgaa cacccgcctg caggtcgagc acccggtcac cgagatgatc accgggctcg
     1141 acctggtgga gtggcagctg cgcgtggcct cgggcgaaaa gctgccgctg gagcaggagc
     1201 aactgcagat ccgcggccat gccctcgagg cgcgcatcta cgccgaggat ccggccaagg
     1261 gcttcctgcc ctccaccggc aagctggtgc acctggcgcc gcccgccgaa tcgctgcacg
     1321 tgcgcgtcga caccggcgtc gaggagggcg acgagatcag cccgcactac gacccgatga
     1381 tcgccaagct gatcgtgtgg gacatcaacc gcgaccgcgc gctcgcccgc atgctgcagg
     1441 ccctggccga ctaccgcgtg gtgggcgtgg ccaacaacat cgagttcctg tcgcgcctca
     1501 ccgcctgccc ggccttcgcc ggcgccgacc tcgacaccgg cctgatcgag cgcgagaagg
     1561 cctacctgtt cccggccgag gaaggcctgc ccgccgaggt gttgcagatc gccgcgctgg
     1621 ccgagctgct gcgcgacgcc gccttcgccg accgccgtgc tgcgcgcagc gccgatccgg
     1681 cctcgccctg gcatgcgcgc gacggctggc gcatgaatgc caccgcctgc cgcagcctgc
     1741 tgttccgcca cggcgagagc gagcacgagg tcgaggtggc ctacctgccc ggcgcctggc
     1801 ggctgacggt gggcggctgc agcgtggtcg cgcgtggcga gctcaacctg cgcggcctgc
     1861 tgcgcgtcga gctcgacggt acccgcatgg acgccaccgt gatcgccgcc gccggccgcc
     1921 gccacgtctt cgccaagggc cgcgcctggc agctcgccgc ggtcgacccg ctgcaccacg
     1981 gcggcgaggg cggcggtgcc gagggcgggc tgatggcgcc gatgccgggc aaggtcatcg
     2041 ccctggtcgc cgccgaaggc gcgaaggtcg agaagggtgc cccgctgctg atcctggagg
     2101 cgatgaagat ggagcacacc atcaccgccc cggccgccgg cacggtcaag gccttccgct
     2161 tcggcgtcgg cgaccaggtc ggcgacggcg ccgagctggt ggagttcgaa gccgccgcag
     2221 catgagtcgc tgctgaccgt cagtcgttgg cacgcgtgcc gatcgcggct tccgccccac
     2281 acgacaagcg cacaccggcc ctgtgggggc gactgtctgt aggagcggcg gaagccgcga
     2341 acaatggcgg catcggtgcg cgccggccgg atcgagcgcg gcgtgcaccc tgacaaagca
     2401 tcatcagaac gagaggagag agggcgacac gatgagtacc cagagctacg tccacggcgc
     2461 atccgacaaa caactgatcg gccagaccat cggccgcttc ttcgacgacg cctgcgcccg
     2521 ccacgccgag cgcgaggcgc tggtggtgcg ccatcagggc gtgcgcctga cctacgcgca
     2581 gttgaagagc cgggtcgacg cgctcgcctg cggcctgatg cgcctcggcc tcgcgcccgg
     2641 tgagcgcatc ggcatctggt cgcagaacaa catggagtgg gcgctgaccc agttcgccag
     2701 cgccaaggcc ggcctggtgc tggtcaacat caaccccgcc taccggcgct ccgagctcga
     2761 gtacgcgctc aacaaggtgg gctgccgcgc gctggtgctg tcgccggcct tcaagaccag
     2821 caactacctc gagatgatcg ccgacctcgc gcccgagctc ggccactgcg aacccggcct
     2881 gctgcgcagc caccgcctgc cggcgctgga gatggtgatc cgcatgggcg ccgacaagtc
     2941 gcccggaatg ctcagcttcg acgacctgct gcgcgcgccc agccgcgagg agctcaccgc
     3001 gctcgccgtg ctgtccgaga agctgcagtt cgacgacccg atcaacatcc agttcacctc
     3061 cggcaccacc ggccatccca agggcgcgac gctgtcgcac cacaacatcc tcaacaacgg
     3121 cttcttcgtc ggcgaggcga tcaagctcgt gccgggcgac cgcctgtgca tcccggtgcc
     3181 gctgtaccac tgcttcggca tggtgatggg caacctcggc tgcctcaccc acggtgccac
     3241 gatggtctac ccggccgagg ccttcgagcc gctggcggtg ctggagacgg tggcgcagga
     3301 aaagtgcacc ggcctctacg gcgtgccgac gatgttcatc gccgcgctcg accatccgcg
     3361 cttcgccgac ttcgatctct ccagcctgcg caccggcatc atggccggca gcccgtgccc
     3421 gatcgaggtc atgaagcggg tgatcggcaa gatgaacatg gcggaagtga ccatcgccta
     3481 cggcatgacc gagacctcgc cggtgagctt ccagagcggc accgacgacc ccatcgaccg
     3541 ccgcgtgtcc accgtcggcc gcgtccagcc gcacctggag gtgaagatcg tcgacaacga
     3601 gggccgcatc gtgccgcgcg gccagtcggg cgagctgtgc acccgcggct actcggtgat
     3661 gctcggctac tgggacgacg aggccaagac caaggaagcg atcgacgccg gcggctggat
     3721 gcacaccggc gacctcgcag tgatcgacga cgagggcttc tgcaacatcg tcggccgcat
     3781 caaggacatg gtgatccgcg gcggcgagaa catctacccg cgcgagatcg aggagttcct
     3841 ctacgctcac cccaaggtgc tcgacgtgca ggtggtcggc atccccgacc agcgcttcgg
     3901 cgaggagctg tgcgcctgga tcatcctgcg cgagggcgag cgcctgtccg aggacgaggt
     3961 gcgcgagtac tgcaagggcc agatcgcgca ctacaagatc ccgcgctaca tccgcttcgt
     4021 cgacagcttc ccgatgaccg tgaccggcaa gatccagaag ttcctgatcc gccagcgcat
     4081 gaaggaagag ctcggcctcg acgaggcgaa gaccgcctga cacagaggat tgatccatga
     4141 ccacatcgaa gctcccgagc gccgtccgca tcgtcgaaat gggcccgcgc gacggcctgc
     4201 agaacgagaa gcagctcgtc tccaccgaca ccaagctcga gctggtgcgt cgcctcgagc
     4261 gcgccgggct gaaggcgatc gagaccacct ccttcgtgtc gcccaagtgg gtgccgcaga
     4321 tgggcgacaa cgccgagctg ctgccgcgcg tgctcgccgc cgcggcgccc ggcgtcgcct
     4381 acccggtgct cacccccaac ctgaaaggct tcgaggccgc cctcgccgcg ggcgcgcacg
     4441 aggtcgcggt gttcggtgcc gcctcggagt ccttcagtca gaagaacatc aactgctcga
     4501 tcgccgagtc gctcgcgcgc ttccgcccgg tcaccgaggc cgcgcacgcc gccggcgtga
     4561 aggtgcgcgg ctacgtctcc tgcgtggtcg gctgccccta cgagggtgcg atcgcgccgc
     4621 aggcggtggc cgatgttgcg gcgacgctgc tggacatggg ctgctacgag gtctcgctcg
     4681 gcgacaccat cggcgtcggc acgcccgcga gcatccagcg catgctcgag gcggtggcga
     4741 aacgtgtgcc ggtggacagg ctcgccggcc attaccacga cacctacggc atggcggtgg
     4801 ccaacgtcta cgcgtcgctg gagctgggcg tggcggtgtt cgacgcctcg gtcggcggcc
     4861 tgggcggctg tccctacgcg gccggcgcct cggggaacgt tgccaccgag gacgtggtct
     4921 ggttgctgaa cgggctcggg atcgacaccg gcatcgacct cgacgtgctg gtggacaccg
     4981 ccgcctggat cagcgctcgg ctcggccgcg atcccgcgtc gcgcgtggcg cgcgccgtgc
     5041 ttgccaagcg cgccaaggcg gcctgcgcct gagcgtccga tgagccgatc ccggccacct
     5101 gcggtgcgct cgggcaggag gccgaaggtg gtcgttgcga gccaaggctt gccggctgct
     5161 tcataatccg tacttcggat cacgaggcgg gccacacgca tggcccgccc gccgccccta
     5221 cagagacgac tgccatgagt gtcccatccc cctgtaccaa catctgccgc atgagccccg
     5281 acaccggctg gtgcgaaggc tgccagcgca cgatcgacga gatcacgcgc tggagtcgta
     5341 cgaccgacga tgaccgccgc ggcatcctcg ccgcggttgc cgagcgccgc gaatggctgg
     5401 gcgcagccgg ccagcccgtg gagacgcggg catgagcggc gacgcgctct gcgtcggcgt
     5461 gtgcatgatc gactgggacg cgggcgtgtg cctgggctgc ggtcgcagcg ccgacgagat
     5521 caacggcatg cccgcatccg cgccggacac gagcgccgtc gcgcagccgg atcccgccgc
     5581 ggtctcggct gcgcggcagg ccggcgtgcc cctgccgccc aacgtcgccg cccgcgtcgg
     5641 ggagggcagc gattgagcgc gcgtccccag ctgcccgccg gcgtgcaggt cttcgagcgt
     5701 ggctggctgt cggccaacaa cgtgctgctg ttcgacggtg acgaggcgac gctgatcgac
     5761 tccggctacc tgagccatgc cgatcagacg gtggggctgc tgcgcgccgc gctcgagggg
     5821 cgccagctga ggcggctcat caacacccac tcgcactccg accacatcgg cggcaacgcc
     5881 cgcgtccagc gcgccttcgg ctgcagcatc accgtgcccg agggcatggc gcgcgcggtc
     5941 gcggagtggg acgaggaggc cttgctgctg agcgtggggg cgcaggccgg cgagcgcttc
     6001 cgccatgacg agacgctcgc gcccggggcg cgcttcgtcg ccggcgagct cgaatggcag
     6061 gcggtggccg tccctggcca cgacatggac gcgctcgcct actacaaccc cgagcgccgc
     6121 atcctgatct cgggcgacgc gctctggcgc gacggcttcg gcatcctgtt cgccgaggtg
     6181 atgggccagg gcgacgcgct cggcgaggcg cgccgcaccc tggaggccat cggccggctc
     6241 gcggtcgatg cggtgatccc cggccacggc gcgcccttcg ccgagttcga cgacgcgctc
     6301 gagcgcgcct tcgcgcgcat tcgcgccttc gaggacgacg gcgcgcgcat ggcgcgcaac
     6361 gcgatccgcg cctgcatcac cttcaagctg ctcgaggtgc gcagcatggc gctcgccgag
     6421 ctgccacgcc acctcgacga gaccccgctc taccgcaccg ccaacgcgcg ctacctcggc
     6481 ctcgacgccg acgcgctcgc ggcctggctg gtgaaggagc tcgagcgcgc cggcgtggcg
     6541 cgcagcgagg acggggcgct ggtggtcctc tgatcgggtt ttcccggggg cgccagttcg
     6601 tcatcgagcc gcaacaagcg gatacaatcg cggctcgttt cccgggaaaa cacaaaaatg
     6661 caagcaaccg tcgactggat caacggctgg gtgtggagcc ccgccctcat ctacctgtgc
     6721 ctgatcgtag gcctgtactt ctccatccgc acccgcttca tgcaggtgcg ccacatcggc
     6781 gagatggtgc gcgcgatgtt ccgcggcaag agctccgcgg cgggcgtgtc gtccttccag
     6841 gccctcacca tcgcgctctc cggccgggtt ggcaccggca acatcgccgg cgtcgccacc
     6901 gcgatcggct tcggcggccc gggcgcgatc ttctggatgt ggatggtggc cttcctcggc
     6961 gccgcgaccg cctacatcga gtcggcgctc ggccagatct acaagaccga gcaccatggc
     7021 ctctaccgcg gcggcccggc ctactacatc gagaagggcc tgggctggcg cgcctacgcg
     7081 atcgtgttcg cggtcgccac cgtgttcgcg tgcggcgtgt tgctgcccgg cgtgcagacc
     7141 aacagcatcg cggccagcat ggagaacgcc ttcggcgtgg cgccggcggt taccggcacc
     7201 atcatcgtga tcctgctcgg cctgatcatc ttcggcggcg tgcgccgtat cgcccaggtc
     7261 acccaggtgg tggtgccctt catggcgctc ggctacgtgc tggctgcggc cgtggtggtg
     7321 gcgctcaacg tcgacaaggt gcccgaggtc gtcgggctga tcctgtcctc ggccttcggt
     7381 ctcgacgcgg gcttcggcgc gatgatcggt ctcgccatcc agtggggcgt caagcgcggc
     7441 gtgtattcca atgaggctgg ccagggcacc ggcccgcacg ccgccgccgc ggccgaggtg
     7501 ccgcacccgg ctgcgcaagg cctggtgcag gccttctcgg tgtacgtcga caccctgttc
     7561 gtgtgctcgg cgaccgcctt catggtgctg atcaccggca cctacaacgt caccggcccg
     7621 gacggcgcgc aggtgttcac cggcctggcc aacatctcgg ccggcactgg cttcacccag
     7681 gcagcgatgg agcaggtgct gccaggcttc ggctcgatgt tcgtggcggt ggcgctgttc
     7741 ttcttcgcct tcaccacggt gctcgcctac tactacatcg ccgagaccaa cgtcgcctac
     7801 ctgacgcgca acctgcgctc cgaggcgctc atcttcgtgc tgcgcgtggc gctgatcggc
     7861 tcggcgttgt acggctgcgt gcgcaccagc gacctggcct ggggcctggg cgacatcggc
     7921 gtcggcctga tggcctggct caacattgtc gccatcctgg tgctgcagaa gccggccctg
     7981 ctggcgctga aggactacga ggcgcagcag gcccaggggc gcctcgagcc gcagttcgat
     8041 ccgcgtccgc tcggaatcga gaacgccgag ctgtgggtga agatcgccga ccgcaggaag
     8101 cgggaaggct gatcgggcgc ggggcgcttc gcgcgcccct tgcaggaccc gcccgccgac
     8161 actgggctat agtgtcggcg ggcgtttttc atccggaagg gcaatgcaga tcgttctaat
     8221 cagcggcttg tcgggctcgg gcaagagcat cgcgctcaac gtgctcgagg acgccgcgta
     8281 ctacgtggtg gacaacctcc cggcggtgct gctgccgcag ctggtggcgc accttcacgg
     8341 cgcgggctgg cggcgggtgg cggtggcggt ggacatgcgc tcgggcgcga gcatcgcggc
     8401 cctgccgcag caggtcgagg cgctgcgtgc gacggtgcgc gacctgcgct tcatcttcct
     8461 cgaggcgcgc gacgacgcgt tgatcgcgcg cttctcggag acgcgccggc gccatccgat
     8521 ggcggtcgac ggctatacgc tcgaagaggc catccagcgc gagcgcgacg cgctcgccag
     8581 cgtggccgag ctcgggcacc gcatcgacac cagcgacctg cacccgaaca cgctgcgcgc
     8641 ctgggtgaag gacttcatcc agatggcccc ggccgagggc atgacgctga tgttcgagtc
     8701 cttcggcttc aagtacggca tcccgctcga cgccgacctc gtcttcgacg tgcgctgcct
     8761 gcccaacccg cactacgacc cgcgcctgcg tccgctcacc gggcgcgacc agccggtgat
     8821 cgacttcctc cagggcgtgc ccgaggtcgg gcgcatgtcg caggacatcc acgacttcgt
     8881 cgccaactgg ctgcccgcct acgtgcgcga caaccgcagc tacctcaccg tggcgatcgg
     8941 ctgtaccggc ggccagcacc gctcggtgta tatcgccgag tggctggccg agcgtttccg
     9001 cggacaggtc gaggtgatcg tgcgccaccg ctcgaccgcg cgccgcgccg cggaccgcgc
     9061 cgccggcaag gtggacgcga acggagacgg gaacgggcag tgaggctgga gcttgccgac
     9121 tggcgcgggc tgctgcgtcc cggcgacgtg ctggtcgcgc tcggcgggct gctggtgtgc
     9181 ggctatgcgc tgctcgcgct gtggcagggt ggggtgccgg acggtgcggt gatccgcgcc
     9241 ggcggcaagg tgatggcgcg ggtggacctg gcgcgcgagc gcacgatcga ggtgcccggc
     9301 ccgctgggcg tcacgctgat cgagatccgt cccgggcgcg cgcgcgtcgc cgccgatccg
     9361 ggaccgcgcc agtactgcgt tcgccagggc tggctcaccc aggccggcgc ggtggcgatc
     9421 tgcgcaccca acgaggtgag cctgagcctg accgggcggg ctgccgacta tgactccctc
     9481 aactattgag ctgaccccta ccgccgagga ccgccgcatc gcgcgccacg cggcggcggc
     9541 gatcgtgctg accgtggccg aggcggcgat cccgctgccg ctgccggggg tcaagccggg
     9601 actggccaac atcgtgaccc tggtggtgct ggcgcgctgg ggctggcgcg aggcggtgtg
     9661 ggtgtcgctg ctgcgcgtgc tcgccggcag cctgctgctc ggccagttcc tcgcccccgg
     9721 cttcttcctg agcctgtcgg gcgcgctcgc cagcctggtg gtgctcggcc tggcgatgca
     9781 cctgccggcg cgctggttcg gcccggtgag ccacagcatc ctcgccgcct tcgcccatat
     9841 cggcgcgcag ctggtggtcg cgcgcctgtg gctggtaccg cacgacgggg tcttctacct
     9901 caccccggtg ttcgcgctcg cggccgtggt gttcggcctg ctcaacggcc tgatcgccgc
     9961 gcgcctgctg cgcgagctgc agcgggtgtc gccgccgcag gctggagatc cgatggaacg
    10021 ctgatccggt agtgccgtcc aaacagccga tgccggcaag gcaacgccgg cgcagcgcag
    10081 ggaggtggca tgcacggacg gtggtggagg tggctcggca cggtgctcgc ggtcgtcagc
    10141 ggcctggtgt tcggctgggt cgcgggctcg ggcctggtga acgcggcacc cgtcgtggcg
    10201 acggatgccg tgatgcgatc gccggtccag ccgccggcag cgagtgcgcc gagcgatcag
    10261 gcgagtgcct tggcaaggtg ctccagcgcg cgcttccagc cgtcctcggc ctcggccttg
    10321 cggtagctcg gccggtagtc ggcgtggaag gcgtggggag cgtcgggata gacgtggatg
    10381 gagctgccgc cgcccgcggc ggagagcgcc gcctgcatct tctccacgtc ggcgagcggg
    10441 atgccctggt cctggccgcc gtagagcccg agcaccggcg catgcagctt gccggcgacg
    10501 tcgagcgggt gctgcggggt gagctccgag acggcgccga cgagacgccc gtaccacgcc
    10561 acccccgcct tcaccgacgg cttgtgcccg gcgtacagcc aggtgatgcg gccgccccag
    10621 cagaagccgg tgatcgcgag gcgggcggga tcgccaccct ggcccgccga ccatgcggcg
    10681 caggcgtcga ggtcggccat gacctgagcg tcgggtacct tggagacgat gttctgcagg
    10741 atcgccggga tgtcgggctg ggtggtcggg tcgccctggc gaaagaacag ctcgggcgcg
    10801 atcgcgaggt agcccgcgtg cgcgaggcgg cggcagacgt cgcggatgtg ctcgtggacg
    10861 ccgaagattt cctgcacgac gaggaccacg ggcaagcggt cgcccgcggc ggggcgtgcg
    10921 taatagaccg gcagctcgcc gccctgcacc gcgatggcgg ccgtgcccgc ggccaggccg
    10981 gtgctcgcgg tgctgatcac ggtgctggca tggacgggct gcacggccag cgcgaagccg
    11041 gcggcggcga cgcccgcgag gaagccgcgg cgatcgaggc gggtggcggg gagcaggctg
    11101 tcgaactggc cgcgctcgtc atcggcggtg tgctgcgcac ggctgggggt ggcttgcatc
    11161 gtggcggtct cctctggggt gtggtggaca tgccccggag agacagcgcc atatgcccgg
    11221 tcgttccgcg cgtggtgcgg gaaatcggcc gcgtaaacgg cgcgcggccc cgaggggccg
    11281 cgtgaggcgc gagagcggcg cgatgccgcc tcgcggtgtg ttgcagacga ctcagcgccg
    11341 gcgcggcggc ggcgcagcgg cggcacccgc cgggcgaccg ggcaggtggc ggaaggtgat
    11401 gcggcccttg ctgaggtcgt agggcgacat ctccagcgac acgttgtcgc cggcgatgat
    11461 gcggatgtgg tgcttgcgca tcttgccgcc cgagtaggcg atgaggttgt gaccgttgtc
    11521 cagcgtcacg cggtagcggc cgtcgggcag cacctcggtg acggaaccgt gcatttcgat
    11581 gagttcttcc ttggccatgt cggggctcct gtaggggttc cgatgcccgc tcgtacgcgg
    11641 gaccggagag gcgcgttccg ccgtacacgg gcctcgaaaa ggtcggacgc cacgttcttg
    11701 tggggcatcg accgtaaaaa gacggcacca gatcggcggg ccggctggaa atgttgcaat
    11761 tgcgctcccg ggccagaagc cgggggcgtg cagcgaaggc gagatcgaag agcgtacgcg
    11821 gggcgctcgg gatcgctgcg aaaagacgat gacgcgctgc gtcacgcaca gtcgtgccgg
    11881 gttgaatgcg tacattccaa accggcaatg gattcgacac aaactatacc agatcaggtc
    11941 ttgccggtcg atggcttcgt gttgcgccgc agcaaaacgt cgagccggtt ggcgaagctg
    12001 cgtgcatcgg ccgccgagaa ggcgctcggc ccgcccgtgt cgacgccggt ggcgcgcagc
    12061 gtgtccatga agttgcgcag gtcgagcagc tcgcggatgt tctcgcgacc gtagagctcg
    12121 ccgcgtggcg acagggcgtg ggcatccttt gccaccaccg cggcggcgag cgggatgtcg
    12181 gcggtgatga cgaggtcgcc ggcgccggca tgctcggcga tgtagcggtc ggcctcgtcg
    12241 aatccgcccg gcacctggat catgcggatc cgcggcgacg cgggcgtgcg caggaactgg
    12301 ttggcgacca gggtgacggg gtgcccagtg cgctcggagg cgcggaacag gatgtccttg
    12361 acgagcaccg gacaggcgtc ggcatcgacc cagatgtgca tggcgggact cctgcgcggg
    12421 ctggcgcaaa agaaaatgcc cggaacgaag tccgggcatt ttcggtgaaa cttggtaggc
    12481 cgtgcgggat tcgaacctgc gaccaacgga ttaaaagtcc gctgctctac cagctgagct
    12541 aacgacccaa aagcgaggcc gaataataat ggcccagcgg ctgggcgtca agcgtcgagg
    12601 tgcgtcgcag gcgtgctgtc gagatgcgcg ccttggcagg cgcacggact acgcaccagg
    12661 ttgcgccgaa ccctgcccgg tcctatagtc ggaccaccct ctcaagccga aggacggcca
    12721 tgaacggccc gcactcttcc ggtccatcga ccgaggcggc attccagccg ctcgtcgatg
    12781 cactcctggt cggtgaccac aagctggctg ccgcggtggc acagcacctc atcgagcagg
    12841 gttgctcgcg cgaacaggtc gtcaccgacg gcctggagca tgcgatgggg cttctcgacg
    12901 acaagtgcac ggtcgagagc ttcaacctgc tcgagatcat gctcgttggc cgtgcggttt
    12961 ctgcggtggt gcgtgtcctc tatccggacg gctacgctcc gaccgagggc cgcgccacct
    13021 tcgtcatcgc caccctcgag ggcgatgtcc acgacctcgg caagaacatc gtgcgcatgg
    13081 tgctcgccgg gaagggtttc cgggtggtcg atctcggtcg cgattgcccg gtcgacgacc
    13141 tggtcggtgc ggcacaacgc gagggcgcgg cggcggtgct cgtcagcggg ctcatcagtc
    13201 cggtggtgag ccaggtacgc aagctcaggc ctgcgctgcg cgcgtgcggg ctcgcgcacg
    13261 tcccggtcgt ggccggtggc gccgcgctga agcagctgcg ccccgaggcg ctcgacgtcg
    13321 attacgtcgc cgagaatgcc ttcgacggcg cgcactatct cgagcgccac gtgagcggcg
    13381 cacccacaac atgaacagcc tggagcgcat cctgcgggcg acccggctgg agccggtgga
    13441 ccgcacaccg cttgtcccgc agctgttcgg ccatgcggcg gtctgcgcgg gcctgtcgtt
    13501 gcgcgattac ctgcacgacg gcgaggcgct ggcacatgcc cagatccgcg cgcgcgagcg
    13561 ctatcgtacc gacgcggtct tcgccttcct ggatttcggt gtcgaagccg aggcgctggg
    13621 cgcgcagctg agtttcgggg acgaccgcta tcccgacgtg gtcggctgcg tgctgggagc
    13681 cgacgacgat cccgcccgcc tccgcctgcc cgaacccgcg agcgccggcc gcatgccggt
    13741 ctgcctgcgg gcgctgcgga ccatgcggca acggctcggg gactccgccc tcgtcgcggg
    13801 ggccgtggca ggcccgatga ccgcgagcgc gcagctctac ggcatcgaga acgcgctttt
    13861 tctcgcgatc gacgatcctc cccgccttgc cgctgcgctc gatttctcca cccggctggc
    13921 catccgctac gggctcgccc agctcgacgc cggggcgcac gccgtgatcg tgttcgatcc
    13981 ggccgcgtcg ccggcggtcg ttccgcccgg ctttttccgc gagttcctcg cgccgcggct
    14041 cgggcgagtc ctggcggccc tgcgcggcgg cggcgcggcc ttcacctggc tcaacatcgc
    14101 cggccccacc gcgggcatcc tcgactgcta tgcgcacatc ggcgccgatg tagcgacctt
    14161 cgactactac ctgagcgctg ccgaggcctc tcgcctgctg ccgcgaacct gcctcgccgg
    14221 aaacctgaag tcgcttgatt tcctggacgc tgctccggac gtggtgaagc gcgaggcgcg
    14281 cggcctggtc gccgccttcg ggggccgcgg cggcttcctg ctgtcgagcg gatgcgagat
    14341 tccgcccgag gccgccgcgg gcaacatcgc tgccatggcg gcggcgctga acgaggattg
    14401 agcgccatgg ccaccctgcg agtccgcgca ggtggggcgc tgcatctgct cgcgtacgat
    14461 cctgacgccg ggaactcgct gcgcgcgatc ctggagccca cggacttccg tgtgcgcacg
    14521 gcctgcctgg ggctgggggc atgcgggctg tgccgggtcc gggtgctcgc cggcgaggtg
    14581 ggtgcgccca ccgcggtcga gcgcgtccag ctcgaggatg ccctcctcgc cgagcgcgtc
    14641 aggctggcgt gccagtgcag gccggtgggc gaagtggaga tcgaggtgct cagtctcgcg
    14701 ccgccgtcga gctggcacgt tccgcccggc gggctggcct cgatcgggac cttgcgctgg
    14761 gaggcggacc ccgcgccgtc gcatgcggtc ccccgtccgc tgggggtcgc ggtcgatctg
    14821 ggaaccagtc acatcagcgt cgccttaatc gatctcatcg gcgcgcggcc gctcgccctg
    14881 cgcgtgggcg cgaacccgca gcgcgcccat ggcgcggatg tgatgacgcg cctcgtcgcg
    14941 gccggtgatc cggatcatgc gcgtgcgctc gccagcctgg cgcgcgcggc cgtgggcgag
    15001 gcgctcggcg agatcgcccg cagcgagggc atcgatctgc ggcgcgtgcg ccgcgtgctc
    15061 gtggtcggca acacggcgat gctgagcctg ctcgcggaca ggaaccacca gcgcctgctc
    15121 gagcccgcca actggtcgct gccgatcgat tgcgcgccgc tcgagaccgc ttcatggggg
    15181 cgagagtggg ggctcgcgcc ggaagcctcg atcgaggtgg tggcgccgct ggcgggcttc
    15241 gtcggatcgg atctgcttgc gggcgtcgtc gccgagcgca tgcccgagct gcgcacgccc
    15301 ggtctgctga tcgatttcgg caccaactcg gagatcgcct tgtggtcggg cgacacgctc
    15361 tgggtgaccg ctaccgccgg ggggccggcg ttcgaggcca gcgcggggcg ggactgcatc
    15421 cctgccgagg ccggcgccgt ggttcgcgtg cgtgaaggcg aggggggcgc gctcgagtgc
    15481 gacatcatcg ccggcgacga gcccaggggg ctttgcggct cgggcctcgt agacctgctg
    15541 gcctgcctgc tgcgacagag gcgcctcggg ccgcgcggcc gcttcagcga cgacagcgag
    15601 cgtgtcgagt tcgaggtgaa cggccgtatg ctcggcctgg gctggcgcga ggtcgatgcc
    15661 ctgcagcgcg cgaaggccgc gatcggcgca ggcatgaagg tgctgtgcgg ctgcgccggc
    15721 gtggatccgt acgcgctgca gcgggtcctg gtcgcgggcc tgttcgggag ccatctcgat
    15781 ctcgacagcg cggcggcgat cggcctgctg ccacgtctcc cggaggggcg cgtggtgctc
    15841 gtcggcaaca ccgcgctcgc gggtgcatgt ggcctgctgc tgtgcgcgga tgcgcggcgc
    15901 atgctcgagc gcgtgcgcgc gtgcgcacgc ttcgtcaatc tcggccgcat ggcggcgttc
    15961 gacgaggcct ttctggacca gcttttcctc caaccgatgg gctccccgcc atgagtgcag
    16021 tgtcatccgg tccgcgcacc ccggtggatg ccgtggtccg taccgcgcaa tatcttgccg
    16081 gcatcgtctc ctatgagggg ctgtggcccc agctcgggcg cctcgtgcgc aacttcttcg
    16141 gtgcggacgt ggccgccttc atcgcccgcg agggggaggg cggcgagcgt tgcctgcact
    16201 gcgagcccga ctgcccgatg ctcgccgcgg cgtgtgcgga ggccaccgcc atggtgttcg
    16261 agagtggctt cctcgccacc gaggcggtgc ggatccccga gccgcacgag gtgatcctgc
    16321 tgcccatcgg ccgcgagcgg cagcgcaccg cctacgtgct catcgcagcc catcggggcg
    16381 ccacggcgct gtcccgcgac acgctggacc tgtatctcgc gctggcgggc ctgatcgaga
    16441 ccacgctcga tcgcatcgcc tcccagcatc gcttcctcag catggccgac aacgtgcccg
    16501 agctgctctt ccagttcgtc gagcacgatg gccgctggat gttcaattat gcgagcggcg
    16561 gcgctcgggc tgcgctcggg ctcgaagccc aggccctgat cgcggatccg gcgttgctgt
    16621 tcgcggggct cgatgaagcc gggggaggcc gcctgctgga ggccctgcgc gccagcgccg
    16681 ccggtcgccg tgtgcatctg ccgctgtgct ggcgggcgcc cgacgggggc ctgcgccacc
    16741 tcctgctcga tgccgtcgct gccaccggag aacagggccg tcccgtctgg gatggcgcgc
    16801 tgcgcgacat cagcgagcag gtccggctcg aggaagagag ccggcgcaac ctggtgcgcc
    16861 tgaacaagag catggaggac gccatccagg cgatcgcgac cacgatcgag aagcgggacc
    16921 cctataccgc gggccaccag cgccgtgtgg ccgatctcgc tgcccgcctc gccgccgccc
    16981 tcggcatgcc cgacgagcag atccacggga tccgcctgac cgcggccatc cacgacatcg
    17041 gcaagatcca cgtgccggcc gagattctga gttaccccgg gcccttgccg gagatcgagt
    17101 tcgccctgat tcgcacccac cccgaggtcg gctacgagat cctcaagaac gtggacttcc
    17161 cgtggccggt cgcggagatg gtgctccagc accacgagca cctggacggg tccggctatc
    17221 cgcgcggctt gcggggcgac gcgatcctgc tcggggcgcg catcatcacg gtcgccgacg
    17281 tcgtcgaggc gatcgccctc taccggccgt accgacccgg cctcggggtc gacaccgcgc
    17341 tggcggagat cgagcgcagc cggggggcgc gctacgatcc cgcagtggtc gatgcgtgcg
    17401 tggaactgtt ccgcgggcag gcttactgct tccccgaaac cgccgatcca ggtcgtgtgt
    17461 tcgcgcgtgc gcccgcacat cgcaagccgg agggatgagg tctagcgggg gcgcgcctgc
    17521 aacctcgcag gcggcgtggt actcgtgtcc ccgcccccgg ccgcgggcgc gcatcgcggt
    17581 gggcgacggc cccggcccgc tcagggcgcg cgcgtcagca gccagtactg gagcttcatc
    17641 gtcgcggagg cgcccgcgat gatcgccgca gtggtgaggg ctgcgccgag cgccagcgtc
    17701 gacagccccg aaactccctg gccgagcgtg cagccgagcg cggtgacgcc accgaagccc
    17761 atcagcaggc cgcccgcgat gtggcgcacg aggtcggcgg ggtcgcggaa gctctcgatg
    17821 cggaagctgc gcgtggccag cgccatcgcc gcggcgccgg cgatcacgcc gagcgcgctg
    17881 gcgatgccga agctcatctg gcggttggcg tcgctccaca gcagcagcag ttccagcgtg
    17941 aaggcctgcg gggcgacgaa gctgagcgac tcggcgcggc cgctgttggt ggcgaggaag
    18001 acctcctcga gggtgtcggg gtgctcggcg atgtggccga ggtggccggt gacgtaccag
    18061 cccgccacca ccgcgaggcc gacgatggcg ccgccgagca gcacctcggg gcggcgcgcg
    18121 tcgcggctcg ccagcgccca ggcgagcagg ccgccgccgg cgagcgcgct ggcggcgagc
    18181 agcgcgctgc cagcgtccat gccggccgcg gcgaggaagg cgggcagggt ctgggcgtgg
    18241 ggcagctgca gcgcgaccgg gtcgagaagc tcgacccgcc acacgccggt gagcccgcgc
    18301 agggtcatcg aggcgccgat ggcgaggaag acgaagacca cgaccgactt gaggttgccg
    18361 ccaccgatgc ggatcagggt cttgccggca cagccggagg cgagcgtcat gccgacgccg
    18421 aaggcgagcc cgccgaccac gtgcgacagc cagggcaggc gggcgccggt gtagatcgtc
    18481 ctggcggggt cgaagagccc gagcgcctgc agtacgcccg tgccgaggac ggcgatggcc
    18541 accgcgagcg cccacatccg catgcgcgtc cagtcgccga tgttcaccgc atcggatacc
    18601 gcgcccatgg tgcagaagcc ggtgcgctgg ctggaggcgc cgaacacggc gccgatcgcg
    18661 aagccgagcc agacgatggt ggaggcggag acgagggcgt ggtccatggg cgcggcgggg
    18721 gctcaggtcg agggcggctg gtagggcgtg gggtcggcga cgccggccgc ggcgaagccg
    18781 gcggcgcgca ggcggcaggc ctcgcagcgg ccgcaggcgc ggccgtcgtc gtcggcctgg
    18841 tagcaggtga cggtgaggcc atagtccacg ccgagggcga cgccgcggcg gatgatgtcg
    18901 gccttggaga gttcgatcag cggcgcgtgg atgcgcagct gcgcgccctc gacgccgacc
    18961 ttggtggcga gccgtgccat gcgctcgaag gcctcgatga aggcgggccg gcagtcgggg
    19021 tagccggagt aatcgaccgc gttcacgccg acgaagatgt cgttggcacc gagcacctcg
    19081 gcccaggcga gcgcgatcga cagcatcacc gtgttgcgcg ccggaacgta ggtcaccggg
    19141 atgccggcgt tgtcctggtc gagcggcacc gcgatgccgg ggtcggtgag cgccgagccg
    19201 ccgaactggc cgagttcgac gctggctgtg cggtgctcgc gtgccccgag cgcctgcgcc
    19261 acccgcttcg aggcgacgag ctcggcggcg tggcgctggc cgtaggcgac ggatagggcg
    19321 taggtctcga agcccatgtc gcgcgcgatc gcgaggcagg tggcggaatc gaggccgccg
    19381 gagaggagga cgacggcgcg gggcggggtg tggaggaggg tcattgcggg gccaatctgg
    19441 taaggcgggt cggggtgggg ctgcccgccg cgtgcgtgcg gtgccgacgg gcgcgagtgg
    19501 cgccgctcag cggccgcgcg cgtcgttcca caggatcttg tggagctgca gctggaagcg
    19561 caccggcaga cggtcgcgca cgatccaccc ggcgagatcg gcgggatcga gggcgccggc
    19621 gacgggcgac agcagcaccg tgcagcgttc ggcgaggcgg tgctcggcga tctgccgcct
    19681 ggcccagtcg tagtcggtgg cgtcggcgag cacgaacttg agctcgtcgc gcgcgttcag
    19741 cagcgcgagg ttctcccagc ggttacgcgc gagctcgccg gagccgggcg ccttgaggtc
    19801 cacgatgcgc gacacgcgcg ggtcgacacc ggcgatgtcg agcgcgccgc tggtctccag
    19861 cgaaacgtcg tgacccgcgt cgcacagtgc ggcgagcagc gcgaggcagc ccttctgcgc
    19921 gagcggctcg cctccggtca cgcagacgtg gcgaaggccg tggcccgcaa cctcggcgag
    19981 gatgtcgtcg agcgtgcggg tctcgccgcc gctgaaggcg taggcggtgt cgcaccagct
    20041 gcagcgcagc gggcagccgg tcaggcgcac gaacacggtg ggcaggccga cgcgggtgga
    20101 ttcgccctgc agcgaggcga agatttcggt gatgcgcagg cgcacggccg cagccggcgc
    20161 cgtctcgaca gccgacatgg gtcagcgcgc gttcaggcgc tggcgggcga cctgggcggc
    20221 gttgctctgc ggatagcgct cgagcagcga ctgcagggta cgcctggcgc cggcggcgtc
    20281 gttcatcgcc tgctggctgt tggccaggcc gagcatggcg tcgggggcga cgttctcctt
    20341 gggatacttg tcgatcacgg tcttgaagtg gcggttcgca ctggcgacgt cgcgcgcctg
    20401 cagtgcggag ttgccggccc agaagtgggc gccggcggtg aagttgccgt tggggtagcg
    20461 ggcgacgaag cgctcgaacg ccgcctgcgc gtccttgtgc ttgccgttct tgagcagcgc
    20521 gagcgcgccc tggtagtcgg ccgactcggt gttcgcggat gccggggctg gcacggaggt
    20581 gggtgcctgg gcgggcgccg cggccggtgc cgccggcgcc gcatcccccg aggcgggggc
    20641 ggcggaggcg ttgcccgccg cgccggattc gaaccggcgc aggcgggcgt cgaggtcgac
    20701 gtagaaatcc ttctggcgct gcttgagcgt ctccacctcg ttggtcagca gttcgatctg
    20761 gccgcgcagg cgcgccagct cggcgcgcat ctgttcgttc tgcatggcga gctcgagctg
    20821 gccgcggctg gtggtctcga tctggccctg aacttcctgg cggagctgga agatctggtt
    20881 gcgcgcctcg gtgtcacccc cgaagagttg ggcgtgggcc ggggcggtcg ggatcaggac
    20941 gagcgctgcg gcgagcggca gaaggcgttt catgtcggga ctctcttaga actcgcccgt
    21001 gtagagcatg tcgccgcgac ggttctcggc gtagcagttc tcggtgcggt cttcgcagcg
    21061 cggcttctct tcacccaggc tcacggactc gatctgcgat tccttggcgc cgagcagcat
    21121 gagggcctgc ttgacgacgt cggcacgctt ctggccgagg gccaggttgt actcgcggct
    21181 gccgcgctcg tcggtgttgc cctggaccag catgttcatc tgcgggttct gcaccaggaa
    21241 gcgggcgtgg gcttcgatca gcgcgcgcgc ttcctgcttg atcacgaagc tgtcgaagtc
    21301 gaagaacacg ctgcgcttgg acaggatgtt gttggggtcg gtcagcgccg cgatgccgct
    21361 accggaggcg ctgccggcgg tcacggtggc gacgccggtg ccacggtcgg tgaccgaggc
    21421 ggcgccgttc tcggggccgg tgctcgagca ggcggccagg gtcagcgcga gcagcgcggg
    21481 gaggacgagt ttcttcatgg gtgatgctcc agtacgagtg ttgatgacag cagagagggg
    21541 tatgcggctg tggcgccgct tcatgattac cggatctgcg gaccccaggc gggttcgcgg
    21601 acatcggcgg cctgcaccgt cagccgctgg cggatgcgcc cgtcagtcga caccgccgac
    21661 agcacgccgc ggccaccggt gtcggtggcg tacaggatca tgcggccgtt gggggcgaag
    21721 ctgggcgatt cgtcgcgtgc cgaatcggtg aggatggtgg tctgccgggt ggcgaggtcc
    21781 tgcacggcca cctggaagcg gccggcattg cgggtgatga aggcgagcag cttgccgtcg
    21841 aacgacaggc gcggcgacac gttgtagttg ccttcgaagc tcacccgctg ggcgctgccg
    21901 ccaccggcag gaatgcggta gatctgcggg ctgccgccgc gatccgaggt gaagtagatg
    21961 tggccgtcgg caccccagaa gggctcggtg tcgatgccgg aggactgcgc gaggcgacgc
    22021 acgccggagc cgtcggcacc gatcgcatag agctgcgaaa ggccatcctt ggtgagcacg
    22081 accgcgagct ggctgccgtc gggcgaccag ctcggcgcgg aattcgagcc cttgaagttg
    22141 gcgaccacgc ggcgctggcc ggtggcgagc gtgtgcacgt agacgatcgg cttcttctgc
    22201 tcgaaggaca cgtaggccag gcgctggcca tcgggcgacc acgagggcga aatgatcggc
    22261 tcgcgcgagc gcagcgcggt ggcggcgttc atgccgtcgg cgtcggcgat ctggagctcg
    22321 aagttggggc cggacttgat cacgtaggcg atgcgggtgg cgaagtagcc cggcaggccg
    22381 gtgagcttct cgtaaacgaa gtcggcgatg cggtggccga ccaggcggtt ctgcgccggg
    22441 ctcatcggca gcgacatggc gccgagctcc tgctgcttct gcgcgtcgaa gaggcggaag
    22501 cgcacgtcgt agcgcccgtc ggacatcggg atcaggctgc cggtgagcac cgcgtccgcg
    22561 ccgcggccgc gcaccgcggc gaggtcgggc gccacggatt cgggcatcgg cagcgggccg
    22621 gtgtcgatca gggtgaacag tccgctgcgc tcgagatcgg cgcgcacgac gtcggtgacg
    22681 ctctgcggca ggcggccctc gttctcgaag atcgggatga tgaccgggaa gcgcgaggcg
    22741 ccggtgccgg tgatctcgat cgagagctgg gcgtgcgcag acagcgcgag gctggcgagc
    22801 aggccggcga ggaagaggcg gaacgcgtgc agtgggcgga atgcgtgcag tgttttgatc
    22861 atgcggggtt ttctccagcc gcggattata gacaggacgg actcaatcgt ccgccagcgg
    22921 acggaatttc agctcgaggg tgcgctcgaa ctggctcttg ttgtccggca gcggcagcgg
    22981 gctcgagcgc cggatcgcgc gctcgatggc ctcatcgagg gccggcacgc ccgacgagcg
    23041 cttgaggcgc acgttgagca cttcgccgct cggtagctga tcgacctcga acagcgcctc
    23101 cgggttgccg gagaggccgg gcggacgcag caggttgccg cgcaccttgg cggcgatcgc
    23161 cgcgcggtac ttgtcgatgt cgccgcccgg cgggccctgc cggcccgggc cggccgcggc
    23221 cgcgcgcgcg ccttcctgcg ccatcaggct ggagaggcgg gcctgctcgg cgcgctgcgt
    23281 ctcctgggcg agacgctgcg ccatgtaatc gtcgatcggc ttgctgtccg gcttcggctt
    23341 gggttcgggt ttggcctgag gcttgggnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    23401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    23461 nnnnnnnggc ttgggttcgg gtttggcctg aggcttgggc tcgggtttcg gctccggctt
    23521 gggctgtggc tttggttccg gcttcggctc gggcttcggc tgcggctttg gttcgggctt
    23581 tggctgcggc ttgggctcgg gcttgggagg ctccggcttc ttctcgggcg ccttggcgac
    23641 gatctcgggc ttggcctggg gcttgggcgg ttcaggcctg ggttcgggct tcggctcagg
    23701 cttgggttcg ggttttggtt ccggtttggg ctcgggttta ggctccggcc ggggctccgg
    23761 tgccggctgc gggcgtgccg cggccggcgc gctgcgcgcc ggggccgagg cgaggccgac
    23821 ctcgagcgcc gcaggcggcg ggctctgcca gcggatgccg aagaacagga acaggaacag
    23881 tcccagatgg accgcgacgg tcaggccgag cgactgccac ttgcctggtg gctcgcggcg
    23941 gggcggtgcg gggcgatccc tcatttctgc gaagtcgtgc tctgggtgac caggctgatc
    24001 ttgcgcacgc cggcgtcgcg cgcggtctcg agcacgtcga tcaccttctg gtagtcgagc
    24061 ttgctgtcgg cggcgaccag gaagggctgt tccgggttct tcgccaccgc gtccttgagc
    24121 gcggtggaca actgctcgcg gcgtaccggg cgcgaggtcc cgctgttgct ggcgcgcagc
    24181 gcgtaggcgc cgtcggcctt gacctcgatg aagatggcct cggactgcgg cggcggcgtg
    24241 cctgcgccgg cggagggcac gttgatcgtg ccctgctgga tcatcggcgc ggtgaccatg
    24301 aagatcacca gcagcaccag catcacgtcg atgtagggca cgacgttgat ctggttcatg
    24361 agacggcgtt ggcgcatcgg tcggtctccg cccgggtcag cgcaggttgc gctgcaggat
    24421 gttggagaac tcttccatga agctctcgaa gcggatgccg aggcgatcga tgtcgtgggc
    24481 gaagcggttg taggcgacga ccgccgggat cgcagcgaac aggccgatcg cggtggccac
    24541 gagggcctcg gcgatgccgg gcgcgacctg ggcaagggtg gcggcgccga cgctggacag
    24601 cccgcggaag gagttcatga tcccccaaac ggtgccgagc aggccgatgt agggcgatac
    24661 cgaacccacc gaggcgagga aggcgaggtg ggcctcgagg tcgtcgatct cgcgctggta
    24721 ggtcgcgcgc atcgcgcggc gggcgccgtc gagcgtggcg ccgtggtcgt ggcccttgcc
    24781 gcgcagcttg gtgaattcgc ggtagccggc ctcgaagatg cgctccatgc cttcggactg
    24841 atggcggccg gccgactcgt agagggtgtt gaggtcgccg ccgctccaga agtcgcgctc
    24901 gaactcgtcg gtctgcgcgc gcgcctggcg gatctggaag gccttgcgga agatccagta
    24961 ccaggagacg agcgacaggc cggccagcag cgccatgacg agctggacga ggacgctcgc
    25021 ctgggagatc aggctgagga tggagaggtc gtgggtgacg gtcatgctgg gctttcgagg
    25081 agggcgtgca gggagtcggg gagggctgcg ggcttcatgc gccgcaggtc tacacaggcc
    25141 acgaggacct gcgcggtgaa gagaagttcg ccgccgcggc ggacttcgtg gtcgaatacc
    25201 aggctcgcgc ggcgccggct gacgatgcgg gcactcacct cgagcgcgtc gtccagccgt
    25261 gccggggcgc ggtagtcggc gtgcaccgag cgcaccacga agccgaggcc ttgttcgtcg
    25321 agcagcgcct gctgggcgac gccgagcgcg cgcagccatt cggtgcgcgt gcgctcacag
    25381 aatttgagat agtttgcgta atagacgaca ccccccgcat cggtgtcttc gtaatagact
    25441 cgaaccggca gggaaaagcg cgacgacgcg gggagcgatt cgccgcccgc gtcggaaacg
    25501 gttttcggtt gcattgcagc attctagccg agccactgcg ccggatgcac gcctgtcgca
    25561 tccttgatcg gtggtttttt tacacgctta ctgcttgttg caaaagcact tttctggaaa
    25621 tgtagttggt cgcggtggcg catgtggcgt ccccgcgaca tcgggaaaca gacgtggcgc
    25681 tccccttctt cggcaggaaa ccggcttcgg ccgcgcccgg cgcgcagcgc gacgcgcgcc
    25741 ccggggtgga ggcgcgcgcc gcgcaggacg atcggccgcc gcccaccgaa ctgtccgcgc
    25801 tcgatttcac cggcaccgac cacggtcgcg cactcgcgcg cgtcgccggg caggtcgaag
    25861 tgcgcgagtg cggcagcggg atcggcgcgg ccttcgagga ggccgcggtg ctgtacgcca
    25921 acggcagcga cgacgacgcg ctcgcggtgc tggaggcggc cgtcggcagc gaggggggcg
    25981 agggagcgtg gctgatgctg ctcgatctct atcgcctgcg tggggagcgc cagcgcttcg
    26041 agtcgcgcgt gctcgattac gccacccgct tcgagcgttc gccgccgccc tgggaagacc
    26101 tgtccggcat ggcgggcaag gcggccggca ccgagctccc gctggtcaac ctgagtggcc
    26161 agctctccgc tgccgccgag cgccagttcg cccagcttgc ccgcatcgcg cgccgcagtg
    26221 gaggggtgcg catcgacgta gccaaggtgc acggggtgga cgatgcgggc tgcggcgtgt
    26281 ggcgcgggct gctcgccggg ttggcggcgg agcgcctgca ggtgacgttg gtcaatgtgc
    26341 gtgcgctcgc cgacatcctc tcgcaggccg tgcaccccgg gcaggcgcag gcgcgcgaca
    26401 cctggctgat gctgctcgaa ctgctgcagt acgccggcga ccaggcgcgc ttcgaagact
    26461 tggcggtgga ttacgcggtc accttcgagg agtcgccgcc ttcctgggag gggcggggga
    26521 cttcgccaca ggcgaccgca gtgcaggtgg gcgagggccc gcaagccgat ccggacgcct
    26581 tcgcgttcgc gggtgagctg tgcggggcgg cgaacgacac cctcaagcgt ttcgccgggt
    26641 ttgcggccga gcgtcgcgag gtccgggtgg actgccgtgg cctgcgccgg atcgatttcg
    26701 tctgtgccgg gacacttttc aatattctcg ccacgctgca ggctcaaggt aaactcgtcg
    26761 gccttcgcga cgtgaacgcc atggttgccg ggctgctgcg ggtcatgagc gtcgacaagg
    26821 tggcccacgt caccctgcgt cattgaacaa cacaccagcc ccgattccct cggggacgga
    26881 gagcattcca tggaacagta tcgcggcacg accatcctgt cggtgcggcg cggcaatcgt
    26941 gtcgcgctcg gcggcgacgg tcaggtcacc ctcggcaaca tcgtcatcaa ggcctccgcg
    27001 cgcaaggtgc gcacgctcta caacggccag atcctcgccg gtttcgccgg cggcaccgcc
    27061 gacgccttca ccttgttcga gcgcttcgag gccaagctcg acaagcatca gggcaacctg
    27121 ctgcgcagcg cggtcgagct cgccaaggac tggcgcaccg accgcatgct gcgccggctc
    27181 gaggccatgc tcgcggtagc cgaccgcgag cattcgctgg tcatcaccgg caacggcgac
    27241 gtgctcgagc ccgagcaggg catcgtggcg atcggcagcg gcggcgccta cgcgcagtcg
    27301 gcggcgcgcg cgctggtcga gaacaccgag ctcgatccca aggacatcgt ctccaaggcg
    27361 ctgtccatcg ccggcgacct gtgcatctac accaatcacc accacaccat cgaagtgctg
    27421 gattgaggcc gaacgcatga cccagatgac cccgccggag atcgtctccg aactcgacaa
    27481 gcacatcgtc ggccaggaca aggccaagaa ggccgtggcg atcgcgttgc gcaaccgctg
    27541 gcggcgtgcg caggtggacg aaccgctgcg cagcgagatc acccccaaga acatcctcat
    27601 gatcggcccc accggcgtcg gcaagaccga gatcgcgcgc cgcctggcgc gcctggccaa
    27661 cgcgcccttc atcaagatcg aggcgaccaa gttcaccgag gtcggctacg tcggccgcga
    27721 cgtggacacc atcatccgcg acctgatgga gatcgccatc aaggacggcc gcgagcgcgc
    27781 gatgaagtcg gtgcgcgacc gcgcactgga cgccgcagag gaccgcgtgc tcgacgccct
    27841 gctgccgccg gcgcgcccgg tcggcttcaa cgccgagcca gagccggcgc aggattcgtc
    27901 cacccggcag aaattccgca agaagctgcg cgagggtgag ctcgacgaca aggagatcga
    27961 gatcgaggtc gccgcgccct cgatgcaggc cgagatcttc gccccgccgg gcatggagga
    28021 gctgacccag cagatccagg gcatgttcca gaacctcggt ggcggcaaga ggaagcagcg
    28081 caagctgcag atccgcgaag cgctgaagct gctcgccgac gaggaggccg cgcgcatgat
    28141 caacgacgag gaggtcaagc tcgaggccgt gcgcgcggtc gagcagaacg gcatcgtgtt
    28201 cctcgacgag gtggacaaga tcgccgcgcg caccgatgcg cacggcgccg acgtgtcccg
    28261 ccagggcgtg cagcgcgacc tgctgccgct ggtcgaaggc acgacgatct ccaccaagta
    28321 cggcatgatc aagaccgacc acatcctgtt catcgccagc ggcgccttcc acctgtccaa
    28381 gccctccgac ctcatccccg agctgcaggg ccgcttcccg atccgtgtcg agctcgagtc
    28441 gctgtcggtc gaggacttcg agcgcatcct gaccagcacc gacgcctgcc tcgtgcgcca
    28501 gtacgaggcc ctgctcgcca ccgacggggt caggctggag ttcgtcgctg cgggcatcag
    28561 gcggctcgcc gagatcgcct atcaggtgaa cgagaagacc gagaacatcg gcgcgcgccg
    28621 tctgtatacg gtgatggaaa agctgctcga agaggtctcc ttcgaggcgg gtcgcagcag
    28681 tacggtcggg accgtggtgg tggatgcggc ctatgtcgat tcgcgcctcg acatgctggc
    28741 gcagcgcgag gatctggcgc gctacgtgct ttgacccgtc tccaggcccg ttcgcgggca
    28801 agctcgttcc gtccgcgcag gcggcgcgga acgcgcctgc cggtgggggg cgtggtgccg
    28861 ccttcttcag ttcgctcccg gcttgtcctg aatgctgatc cgaatcgtct cgatcctgtt
    28921 cccgctgttc gcgatcaccg cgctcggcta tttcgtcggc cggcgcatga agccggatct
    28981 gagccatgcg aacaagctga acatggatgt cttcgtgccg gcgctggtgt tcggcgcgct
    29041 ggtcggcaag gattttcgcc tcggagagta cctgccgctg ctgttcgcga ccgtggtcat
    29101 catcgtgggg tcgggcgtgg tcggctggct ggtggcgcgg tcggccggca tcgccaccaa
    29161 gaccctggtg ccgccgatga tgttcaacaa ctgcggcaac ctcggcctgc cccttgcggt
    29221 gctcgccttc ggcgagtcgg cgctggcgcc ggccgtggtc atgttcgtgg tgtcgaacgt
    29281 gatccacttc tcctacggtg catggctgct ggatcaccac accaggctga cgacggtgtg
    29341 gcgttccccc tccatcctgg cgacgatcgc ggggctgacg gttggtttcc tcggcatcga
    29401 ggtatggccg cccttgctga tgtcgatcga gatggtcggc gacatctcga tcccgctgat
    29461 gctgtttgcg ctcggcgtgc gtctggccga ttcgcggatc agcgcggtgg gcttcggtct
    29521 cttcggcgcg gtgctgagac ctgtggttgg catggcgctg gcctggggcc tgctgcaggt
    29581 gctcgagctg ccgccgcgcg agcaggcgct ggtgctggtg ttcggcgccc tgccgccggc
    29641 cgtgctgaac tacatgttcg ccgagcgtta cgatcaggag cccgacaagg tggcctcgat
    29701 ggtcttgatc ggcaacgtcg cggcggtagt cttcctgccg attgcgctgg cgctggtgct
    29761 cgactgaggg cgcgcggctt cactcgcgcg cgcgtccgcc atcctgttgc atcagcttgc
    29821 ccagcaggtc caccggtacc ggaaacacca gcgtcgagct cttgtccccc gccacctggg
    29881 tgagcgtctg caggtagcgc agctgcatcg ccgccggttc ccgggacagc atctgcgccg
    29941 cttcgagcag cgactgtgcg gcctgcttct cgccttcggc gtggattacc ttggcgcggc
    30001 gttcgcgctc ggcttcggcc tgacgggcga tggcgcgcac catgctttcg ttgaggtcga
    30061 tgtgcttgat ctcgacgttg gccaccttga tgccccagga gtcggtctgc gcgtcgagga
    30121 tctgctgcac gtcgaggttg agtcgttcgc gctcggcgag catctcgtcg agctcgtgct
    30181 tgccgagcac cgcgcgcagc gtggtctggg cgagctggct ggtggccatg agaaagttct
    30241 cgacctggat gatggccttc tccggatcga tgacacgaaa gaacacgatc gcattgacct
    30301 tgaccgagac gttgtcgcgc gagatgacgt cctgcgaggg gacgtccatg gtcaccacgc
    30361 gcaggtccac cttgaccatc tgctggatgc cggggatcac gatcaccagg ccagggccct
    30421 tgaccttcca gaagcgtccg agcaggaaga tgacgccgcg ctcgtattcg cgcaggatct
    30481 tgatcgaggc gacgacgagg aagatgagca gcaaaaagag cggggcaagc ccgaattgaa
    30541 ggtcgatcat gatgaggtgc tccctggggt gacgtggtga gtgtccggcg cggccgagtc
    30601 cggacccggc gcgggagctg ccgcgtcgga ctgcgccgcg atcggggtga ccatcagggt
    30661 gaggccgtcg atgcccgcca cgcgcacacg cccgcccggc gcgagcgctt cagcactgcg
    30721 cgcgcgccag tgctcgccat gcaccgcgat ccaccagtcg ccgtcgtcgg tggcacgctc
    30781 gaccacaccg agggcgccga gcatctcctc gctgccgctg accacgggcc ggcgcaggct
    30841 gcgcgcggcg aagctgccga tggcgatgat gactgcggcg ctggcgagcg ccatgccgac
    30901 gatcagtgcg atcgggatgc cgaagccggg catgtcggcg tccatcagga acaggccgcc
    30961 gaccacgaag gcgatgatgc cgcccacgcc gagcacgccg aagctgggca ggaaggcctc
    31021 ggccagcatc aggccggcgc ccaccgcaag cagcagcacg cctgcccagt tcaccggcag
    31081 cagctggaag gcgtagagcg cgatcagcag cgagatcgcg cccgccacgc cgggcacgcc
    31141 gaagccgggc gaggtgaact cgaagaacag cccgtagatg ccgatcatca tcaggatcag
    31201 cgccacctgc gggttggcga gcgcggcgag gatgcggttg cgccagtccg gctccatgcg
    31261 ctcgatggcg atgccggcgg tggcgagggt gcgcgtgccg tcgagcacgg cgacctcgcg
    31321 gccgtcgagc cgcttcagca gggagggggt gtcgatggcg atgagctcga tgacgccttt
    31381 cgccagcgcc tcctcggcgg acaggctggc ggcctcgcgc accgcgcgct cggcgaagtc
    31441 gacgtcgcgc ccgcgcagct gggccaggct gcggatgtag gcggtggcgt cggacatgga
    31501 cttggcggcc atggcgtcgg tgggggccgc gctgcgctgc gccgctgctg gtgacgaagg
    31561 cgcttcaatg acgggtcgat cggacgcgga cggcggcgcg ttcgcttcgt cgtccctgat
    31621 ctccggtgtg gtttccgggc tgcggtttgc gctggcgggc ggcgattggg cgcgcgcgcg
    31681 ggggggtgat gcgcccgacg tggagcccga cccatcccgc tccgagcccg cagcctcggc
    31741 cggtgccgac tcgtcgccga gcggcggcat gcgtccgggc tgcgcaccgc cgatgccgat
    31801 cgccacgggg gtggccgcgc cgaggttggt ggccggcgcc atggcggcga tgtggctcgc
    31861 gtacaggatg taggtaccgg cgctcgccgc gcgcgcgccc tccggggaga cgaaggtggc
    31921 caccggcacc ggcgaggcga ggatgtcctt gatgatcgaa cgcatcgagg tgtcgagccc
    31981 gcccggggtg tcgagctcga ttaccaccag ctgggcgccc gtgctggcgg cgcgtgtcag
    32041 tcccttgtgg atgtagtcgg cgctggcggg gccgatggcg ccgtccaccc gcagcaccag
    32101 cgcacccgcc gcgctcgatc cggcctgcga tgcgagcagg agcagcacca gcccgatcaa
    32161 ggccaggatg gcgctcgtcg aagtgcgcag cgccgagggg ggaggagcgg gcattccagt
    32221 ctctccgtcg cagtccgcgg gcggatggcc cacggctctt caatcggagt gtagaagcca
    32281 tccccgagtt ctcaagcacg ccgactcttt agccgcttgc aagtggtgaa cgccgtggtc
    32341 cgggcgctcg gtgccacgca ttccacccgc cctcctttgt cgcactggcc gtcccggtgc
    32401 aagggcttca atggccgccg aagcggtcca tgcgccggcg gtcgcgcttg gtggggcggc
    32461 cgtgcaggtc ggcgcccggg gtggcggcga gcttgcgcaa ctcgcgggcg tgctcgcgcg
    32521 cagcgatgct ctcggcggtc tcttcgtaca gggtttgcgc caccgtggcc gagccgcgcc
    32581 ggtcggcgat cgcgcacacg agtaccgtgc gcgtctcctc accgatggtg atgtcgagcc
    32641 ggtcgcccgg cttgacgtcg cgcgcgggtt tcaccgtgat gccgttgagc ttgaccttgc
    32701 cgccgtcgac cgcctcggtc gccgccgtgc ggtgcttgta gaagcgcgcc gcccacaacc
    32761 atttgtcgag gcgggtgcgt gcgggatcgg tgagtgggtg tgcgggcatg gctgggcgct
    32821 gcggcgaggg ggcggacgtg aaacggcgcg gtcgacatta tcgacagcgc cgtgcccaga
    32881 ggcaaagccc gacctcgcgc gcgggccagc tcccgatgca gcccgcggcg gagatcagaa
    32941 caacccggcg atcgaagtga tcaggccctt cttcagctcg ggcagcgcct cctcgaaggc
    33001 gagattgacc ttgttcgcgc tcgagccgat gcgggtctgg taggtcttgt aggacgactc
    33061 ctcgtcgtag gacacctgcg agccgccgct gttgccttgg cgcaggctgt ggttcgagct
    33121 caccttcgcc ttgccggcgc cgcggatgcg ctccttgatc tgcaggtcgg tgatcatcga
    33181 gaagtacacg tccttgaccg cggcgccggc gatgccctcg gccagcgagc cgatcaggcc
    33241 ggcggcggcg atgccgcggc cgctggcgcc gccggcgtag gccgcgccgg cgcccagcac
    33301 caggccgccc gaggcggcga ccccgtagcc ctggttgacc gccgcctcga tcgcagtggg
    33361 tgccgacttg ccgacctgca ggatgttggc ctgcaggatg tagtgcgccg cgtccgggtc
    33421 ctgcagcagg gtatagccct tggcctgcag cgcggcggcg atctcgtcat tcaccgcgag
    33481 gtcgggcttg tcggaggtgt tgcggatctg caggaagatg gtgcgcttgt cggcgccgac
    33541 cgggtcgagg aagaccgtat ccgacatctt ggtctgcacg tcgaggtcgc gtttgctgat
    33601 ggcgacgtgg gcggcggcgc aaccggtgag gacgaaggcg gcggcggtga tgagggcgat
    33661 tcgcttgagc atcgggagac ttcctcgagg acggatggag agggcagggc acggatttcg
    33721 cagtgatccg gagatgactt cgcaggggct tccgttacag gcgcatgtca tatgaaattc
    33781 gattatagag tccgatccgc ctttttgtca ttcatttgaa atgctgaatg actttcttcg
    33841 aggcccgtaa acgaagaacc ccggcgccct tgcgggggcc ggggttcgat cgcagcggaa
    33901 gactggcgcg atcagccgat catgcctgcg cccacggtgt tgttggtgct ttcgtcgatg
    33961 atgatgaagg cgccggtggc gcggttgtcg gcgtagcggt cggcgacgat cggttgcgcg
    34021 agcttgagcg ttacccgggc gatgtcgttc atcgccaagc cgttggtggc ctcctgctcg
    34081 agcgtgttta catcgagccg gtagtcgatc ttcgcgagct tggccttcac ctcgcgggtg
    34141 gtgtggcgca ccagataggt gcgtgccgga gacagcggag tctcggacag ccagcatacg
    34201 gtggcgtcga tctgcttgac cggctcgggc gcctcggcgg acttgacgat gaggtcgccg
    34261 cgcgagatgt cgatctcgtc ctcgagcagc agggtcaccg actgctcgtg gatggcgcgc
    34321 ggcaggctct caccgccgag ctcgatcttc ctgactcggc tgctggctcc cgagggcagc
    34381 acggtgacag cgtcgccgac ggcgatctcg cccgattcga cccggcccat gaagccgcgg
    34441 tagtcgtgca gttcggggtt ggcggagtcc tgcgggcggc atacgaactg caccgggaag
    34501 cggaagtcct cggcctgctc ggtgtgcgct gcgggggcgt tctcgaggat gtcgagcagc
    34561 gtcgggccgt cgtaccaggc gaggcgctcg ccgcggtcga cgatcatgtc gccttcgagc
    34621 gccgagatcg ggatgaagcg cacgtccttg atgccgagcc tggcggcgaa ggcgaggtat
    34681 tcggccttga tgcgctcgaa cacggcctgg tcgtagtcga ccaggtccat cttgttgacc
    34741 gcgaccagca ggtgggggat gccgaccagg ctggccagat aggagtggcg gcgggtctgg
    34801 gtaagcacgc ccttgcgcgc gtcgatgagg atgatggcga ggttggcggt ggaggccgcg
    34861 gtaaccatgt tgcgggtgta ctgctcgtgg ccgggggcgt cggcgatgat gtacttgcgc
    34921 cggccggtgg agaagtagcg gtaggcgacg tcgatggtga tgccctgttc gcgttcggcc
    34981 tgcaggccgt cggtgagcag cgacaggtcg accgcgctca tgccgcgctt ggcggaggtc
    35041 ttctcgatgg cgttgagggt gtcggcgagg atggtcttgg tgtcgaacag caggcggccg
    35101 atcagggtgc tcttgccgtc gtcgacgctg ccgcaggtga ggaagcgcaa caggccgttg
    35161 tcgatgtcgg ggaggttttc aagggcggac atggtttgga ttccgtgcaa ggtgaggcgc
    35221 gaggcgtgag gcgtgaggcg tgaggcgtca ggaggcgtga agcgctcaga agtaaccttc
    35281 cttcttccgc tgctccatcg acgcttccga agtctggtca tccatccgcg tcgcaccgcg
    35341 ctcggtgatc gtcgtggtcg cggtctcggc gaggatcttc tccaccgtat ccgcatccga
    35401 ctccaccggt gccgtgcagg tgatgtcgcc cacggtgcgg aagcgcacca gcacgtcctc
    35461 gaccacgtcg ccgtccttgg ccggggtgag ctcggtcacc ggctgcagca ggccgctctt
    35521 gcgcaccacc gggcgcacat gcgcgaagta gatcgacggc agctccagct gctcgcgctg
    35581 gatgtactgc cacacgtcga gctcggtcca gttgctgatc gggaaggcgc ggatgttctc
    35641 gcccttgtgg ctgcgcgcgt tgtacaggtt ccacagctcg ggacgctggt tcttcgggtc
    35701 ccactgaccg aactcgtcgc ggaagctcat gatgcgctcc ttggcgcgcg ccttctcctc
    35761 gtcgcggcgg gcgccgccga tgcaggcgtc gaagccgaac tcctcgatcg cctccagcag
    35821 cgtcaccgac tggtgcttgt tgcgcgactc gccggcgtgc ttgagcacca cggtaccgcg
    35881 cgccatcgag tcttccaccg agcgcacgat caggcgttcg cccagttcgg cggcgcgctt
    35941 gtcgcggaag tcggtgacct ccttgtagtt gtggccggtg tcgatgtgca tcagcgggaa
    36001 ggggaagcgg cccgggcgga aggccttctc ggccaggcgc agcaggcaga tcgagtcctt
    36061 gccgccggag aacagcagca ccgggttggc gcactggccg gcgacctcgc gcaggatgtg
    36121 gatggcttcg gcctcgagcc agtcgaggtg ggacagcgtc tgtttggtca gcgtggacat
    36181 ggtgcgatta ccgttgcgga tgcttgatcg gatgggttcg gaatgcgcgc agcgccgcct
    36241 tgaggccggc gcgcaacgcg agcaggcgct gctgcaggct gcggcgaccg gcgccgatcg
    36301 ccgggctgtg cgtggcctgg gcggggtgct tgccgttcat ggctcagctt gccttgacgt
    36361 ggagaccgca ctccttggtc tccggattct cccaccacca gcgtccggcg cgtacgtcct
    36421 cgccgaccgc gatcgcgcgc gtgcagggcg cgcagccgat gctggggtag aactggtcgt
    36481 gcagggcgtt gtacggcacc tcgttgatcc ggatgtaggc ccacacctcg gtctcgctcc
    36541 agtccgagag cgggttgagc ttctccaggc cgttggcggt gtcggtctcg cggaccggca
    36601 ggccggagcg ggtgaccgac tgcgccgcgc gcaggccggt gatccaggcc ttgcggccgg
    36661 cgagcgcgcg gcgcagcggc tccatcttgc gtacgccgca gcaggccttg cgcagctcga
    36721 ccgagtcgta gaaggcgttg atgccgtggc cgcgcacgta ctgttcgacc gcgccggcgt
    36781 ccgggaagta gatctcgagc ttcgtgtcgt agcgccgctc gacctcgccg atcagcgtgt
    36841 aggtctcggc gggcagtcgc ccggtgtcga gcgagaagac ggtgatcggc agggcgtgcg
    36901 acaggatcag gtcggtcagc accatgtctt cggcgccgaa gctgttggcg aaggcgagct
    36961 cgccatgcgc gccgaactcg gccacggcct cgcgcagcag cgcgagcgcg gcggcggact
    37021 ttgcgcccac ggtggcgcgc agggcgtcgg tcagcgcggg ctgggtggct gcgttggcgg
    37081 gcgcggggcg cagcgcggag acggcggcgt tcatggctgc acctcgtggc cgttgccgcg
    37141 ttcgacacgg cggaacagcg gcagcggatc cttgaccgag cgctggtagg gctgggtgaa
    37201 gtcgtcgagg ctggcgatgg cggcctcgag ctgttcgtcg gtgtagcgct cggcctgcgg
    37261 ctgcagggcg tcgaagccgc agcgcgtcat gtagttgaac tggtcgcgca gtacctggcc
    37321 gatcgcacgc agctcgcccc ggtagccgta gcgggtgcgc agcagagtgg cggcggagta
    37381 gctgcggccg tcggtgaact tggggaagtg caggccgacg aactgcagca ggccgaggtc
    37441 ttcagcgagc gcggcgacgt cctcgcccgc ggccagccac acgcccacct cgccgctgcg
    37501 cgcacgcgcc agcagctcgt cgcggcgcgc ctgccacacg gcgagcggca cgagcacggg
    37561 gccggcgggg acggcgatgt cggtgggcgc ctcgccctcg gcgaggctaa cggtcaggcg
    37621 gttgtcggcg acgacgcggc cgttcttgat gatcttgtca gacatgggcg gccttccttt
    37681 gcggctggcg gtcggcatac acgcgggcct tgaagggctc ggtgccgacg cgttgaacgg
    37741 tgtcgatgaa gcgctcgtcc tcgaagcgca gttctacgta ggtctcgagc agcttctcga
    37801 tcacgccgac cacctcgtcg agggcgaagg aggggccgat caccttgccg agcgtggtgc
    37861 cgttgccctg ggtgccgccg atgctcacct ggtaccactc ctggtcgttc ttatcgacgc
    37921 cgaggatgcc gatgtggccg acgtggtggt ggccacagga gttcatgcag ccggagatgt
    37981 tgaggtcgat ctcgccgatg tcgtgctggt agtcgaggtc gtcgaagcgg cgctggatgg
    38041 cgtcggcgat cgggatcgag cgcgcgttgg cgaggctgca gaagtcgccg ccgggacagc
    38101 agatgatgtc ggtcagcagg ccgatgttcg gcgtcgccag tccggcggcg cgcgccgcct
    38161 gccacagcgc gaagaggtcg gcgcggcgaa cgtcggcgag cgcgacgttc tgctcgtgca
    38221 gcatgcgcgc ctcgccgaag ctgaagcggt cggccaggtc ggcgatcagg tccatctgct
    38281 cggcggtgac gtcgcccggg gcggtcccgg tcttcttcag cgacaggatc accgcggcgt
    38341 agccgggctg gcggtgggca cgcacgttgc gcttgaccca ggtggcgaag gccttgttgt
    38401 cggcgagcag cgcgtcgaag gcggcgtcgt gcgtgggcag ggcctcgtag gcgggcgggg
    38461 cgaagtgggc cgacacgcgc gccagctcgg ccgcggtgat ggtgttgggg ccgtccttgg
    38521 aattggccca ttcttcttcc acctcgcggg cgaaggcttc cggcccgagc gccttgacga
    38581 ggatcttgat gcgcgccttc cacaggttgt cgcggcggcc ccagcggtta tagacgcgca
    38641 ggatggcctc gcagtagctg atcaggtgct gccagggcag gaagggcttg atctcctcgc
    38701 ccaggatcgg ggtacggccg aggccgccgc ccaccagcac gcgaaagccg agctcgccgt
    38761 ctgcgttgcg caccaggtcg aggccgatgt cgtagacgcg cagcaccacg cggtcttcag
    38821 ccgcgctgtt gaaggcgatc ttgaacttgc gcggcaggaa ggcgaactcc gggttgtagg
    38881 tcgcccactg gcgcaggatc tcggcgaagg ggcgaggatc ggcgacctcg tcggcggcca
    38941 cgccggcgaa ggggtcggcg gtgatgttgc ggatgcagtt gcccgaggtc tggttggcgt
    39001 gcatctgcac gctggccagc tcggcgagca tctccggcac gtcctcgagc ttgggccagt
    39061 tgaactgcac gttggtgcgg gtggtgaagt gggcgtaacc gcggtcgtag ccgcgcgcga
    39121 ggtgggcgag cttcctcagc tggcggctgg cgaggtggcc gtagggcacc gagatgcgga
    39181 acatcggcgc gtggcgctgg atgtagaggc cgttctgcag gcgcagcgga cggaactcgt
    39241 cggccgagag ctcgccggcc aggtgacgcc gcatctggtc gcggaactgg gcgacgcgct
    39301 ggtcgagcag gcgctggtcg tgttcgtcgt attggtacat gtgggctctc tctgtcgtat
    39361 gcgtgaattc gggccgggga ggggcttcgt gttcttgagc gctgcgcttc agtgcgccat
    39421 cagcttggcg ccgaccagca ccagcatcgc cgccaggatc gggcgcagga tgcggtcggg
    39481 caccttggtg gagatgtggc tgccaagcca gatcccgggc agtgagccga ccagcaggct
    39541 gcccagcagc agccagtcga cgctgccgag gaaccagtgg ccgatgccgg cgaccgcggt
    39601 cagcggcacg gcgtgggcga tgtccgagcc gacgatgcgc agcgcgggca tggccgggta
    39661 gaggaagaac agcgcggtga cgccgagcgc gccggcgccc accgaggaga tcgacaccag
    39721 cacgccgagc acggcgccgg tgatgatggt gagacgggcg gtgcgcgccg gatcagcggg
    39781 gcggccgccg gagcgcgcca ccgcgtaggc ctggatgcgc ttgcggaaga tcagcgccac
    39841 cgcggtcagc accagcgcca cgccgagcgc gacctggatc aggtgggcag cgccctcgat
    39901 accgccgggg gcgaagtgcc cgatcagcgc cagcgtgatc gccgccgccg ggatgctgcc
    39961 ggtggcgagc aggcgggtga tcttccagtc caccgtgccc ttgagcccgt gcgccagggt
    40021 gcccccggcc ttggtggttg cggcgtagag caggtcggtg ccgaccgcca ccgaggggtg
    40081 gatgccgaac atcagcacca gcagcggcgt catcaaggac ccgcccccaa cgccggtgag
    40141 accgacgatg gcaccgactg cgaaaccggc gatggtgtag gcgaagtcca tgtaatgcgc
    40201 tcctggatgg tgcggcgcat cgtaaggact tcgtttaagt gcaagaagcg gtttggagtt
    40261 agactttaag aactggttgt tatatnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    40321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    40381 nnnnngtgct gcgcgacctc gacaacctgc agcaggtggg cgacgagttc gccaacgagg
    40441 cggtcggccg cctgtcgatc gccaccaccc acacccaggc gcgctacgtg ctgcccgacg
    40501 tggtccgccg cttcatgcag cgctatccgc aggtcaagct cgagctgcac cagggcaacc
    40561 cgcgccaggt gtgcgagatg gtgctcgacg gcagcgccga catcgcgatc gccaccgagg
    40621 ccatcgccga gtacgacgag ctggtgatgc tgccgtgtta tcagtggaac cgctgtgtcg
    40681 ttgccacccc gcgccatccc atcctgcagg ccgcgccact gacgctggaa gagatcgcgc
    40741 gctacccgct gatcacctac gacgacgcct tcaccggtcg cggccagatc aacaaggcct
    40801 tcctcggccg cggcctcaag cccaaggtgg tgctgaccgc gatcgactcg gacgtgatca
    40861 agaagtatgt cgagatggac ctgggcatcg gcatcctcgc gcgcatggcc tacgacccgg
    40921 cggaggaccg caggctgggg atggtcgacg cctcgcacct cttcgagtcg agcaccaccc
    40981 gcatcgggct gcgcaagcgc gcctggctgc gcgcctatgt gtacgccttc atcgagggct
    41041 tcgcgccgca tctgtcgcgg cgtatggtcg aggccgcgct cgcgggcggc ggcaccgatc
    41101 cagggctgtg acgcaggggc gcggcggcgc ccaggcccat cgtcggggcc tcgctcaggc
    41161 gcgctcgaac cagcgccgca ggcgtgcccc gcgcagcccg gcaccgaggc cggcgatcag
    41221 gcgcacgcgt gccttcaggg gatcgagcgc gccggcgtcg agccagttgg cgggcgcgtt
    41281 ctcatggtgc cggcgcacgc cgccgccgca gcggctggcg agcacgaccg gcaccgcgtt
    41341 gggcaactct tccagcgcgg gccgccaggc ctccggcagg ctggcgttac cgggcagggc
    41401 cagcaccagc ccggcggcgc cgttgagcaa ctgggcgcgc gcgagcgcgc gcgccaccgc
    41461 cgaggcgagc gcgggcgagc tgcccgcagc cacggtcagc agctctaccg gcggcaggtg
    41521 ctgcagctcg tccggcagca cgacccggct gtagcgcgag ggcgcgagcg cctgcagcgc
    41581 ggcgtcgctg gcgagcgtgg tgagcgcgcc ctcgaacgcg aacgcatcca ccgccgaggg
    41641 gtggcgtttg gcgagggcgg ccgcaggcac gatgcggtcg ccgatcaccg ccagcacccc
    41701 tgcgcgcgcg gccgccgggc ggcaggcgag ctcgaccgcc tggtagaggt tgagcgggcc
    41761 gtcggccgac agcgcggtgg ccgggcgcat cgccgccgtc atcaccaccg gcttggtggg
    41821 ggcgacggtg atgttgagga aacaggccgt ctcttccagc gtgtcggtgc catgggtgat
    41881 gacgatgccg tcgaccgcgg ggtcgtccat cagccgctgc acacggcgcg acagcaccag
    41941 ccagtgctgc ggggtcatgt ccttgctgtc gacgctgaag acctgggtgg cgtcgatgcg
    42001 ggcgagctcg gccagctgcg gcacggcggc gagcagggcc tcggggccga gctggccggc
    42061 ggtgtagtcg cgggtgtcgg tggccgagcc ggcggtgccg gcgatggtgc cgccggtggc
    42121 gaggagcgcg atgcgcggct tgcgcaggat ctggagggcg ttgtgctgcg ggatcatgtg
    42181 gggcgtggat tcgttcgagg ggcggtcagg cgttgccggt gtcgcgcagg gcgatgatgc
    42241 gccgctcgcg ttcttgttcg accaggcgga gcgccgcgtc gggcgggatg cccagggtct
    42301 ccagcaccca gccggtgagc ttgaggctgg actccagggt ttcgggcacc accaccgagg
    42361 cgccggcctc gcgcagcagc agcgcgtgct tctcgtcgcg tgcgcgggcg atgatgcgca
    42421 tcatcggcac catgcggcgg atgccgtgca ccgcgttgat cgcggcggcg gtgtggtcca
    42481 tggtgagcac caccgcgcgc gcctggtcga tgcgcagctt gcgcagcagc tccgggcggc
    42541 tggcgtcgcc gaacaccagc ggcacgccgg ccttgcgctg gtgggcgatg agctgggcgt
    42601 tgttctcgat ggcgatgtag ctcacgcctt gctcttccag catctgcccg acgagctggc
    42661 cgacgcggcc atagccggcg atgatcacgt gcccgtcgag ctcgccgagc tcggtgtcct
    42721 cttcttctgc cggcggcgcg atgcggcggt cgatgtggtc gcccaggctc tgcccgaggc
    42781 gagcgaccac gggcgcggcc agcatcgaca cgccgaccac gatcagcatg aactgcccca
    42841 cctgacgctc gagcaggccg agcgcgagcg ccatgccgat cacgatgaag gcgaattcgc
    42901 cgccctggcc gagcagcagg ccgccctcgg ccgagcgccc ccacgacagg ccgaagaccc
    42961 gcagcagcac gaacacgatc agcgccttca tggccagcag gccgacgacc gagagcggga
    43021 tccacagcgg ctcggcgagc agcgcgcgca ggtcgatgcc catgccgacc gacatgaaga
    43081 acaggcccat cagcaggccc ttgaagggct cgatggtgat ctcgacctcg tgacggaatt
    43141 cggtctcggc gatgatcagg ccggcgagca gggcgccgag cgccatcgac aggccggcca
    43201 cccaggtcag cgcggccacg cccagggtgg tgagcagggt gagcgcggtg aaggtgtcgg
    43261 gctgcttgtc gaccgcgatc tggtggaaga gcggacgcac cacgcgacgg ccgatgaggt
    43321 agatgcccac cacggtgagc acgcccttga gcattgcgag gccgagcagg ccggcgaagc
    43381 tgccctcacc ggaggaggcg ccgaggatgc tgatcagcac cagcagcggc accaccgcga
    43441 ggtcctggaa gagaaggatc gcgaacgagg cctggccgag cggcgtgccg agttcgtggc
    43501 gctggatcag cagctgcatg acgatcgcgg tggacgagaa ggccagcacc acgccgagga
    43561 tgaccgccgc ctcgatgccg ttgccgaacc acagcgcgag cgcgccgacc gcgcccgccg
    43621 acagcgcgac ctgcaggccg ccgagtccga acaccagccg gcgcatcgac cacaggcgct
    43681 cgaccgacat ctcgaggccg atcatgaaca tcaggaagat gaccccgagc tcggcgagga
    43741 actccacctg gtccgggcgc gcgaaggtga accacgacag cggcggccag gcctgcgcga
    43801 gcgaggcaag gccgtaaggg ccgagcagca ccccgaccga caggaagccg agcacgggat
    43861 tgatcttcag ccgcgacagc agcggcatca gcaccccgct cagcgcgagg aagaggatga
    43921 tttccttgag gaagggaaag ctgtcgtgcg aatccatgcg ggccttgtgc gagggctatc
    43981 caaacagtct acgccacacc gcccgcgggc gcggcgaaag acttggcatc cgcgccgtca
    44041 tcccggacgc cggccgccgc gctgtcggcc gtctcttcct gctgctgcag cagccacatc
    44101 tgcgcatagg cgcctccctg cgccagcagc agggcgtgcc gcccgcgttc cacgatgcgc
    44161 cccttgtcca gcacgatgat ctcgtcggcg tccatgatgg tcgacagccg gtgcgcgatc
    44221 accagcgcgg tgcggccttc ggcggcgcgc tcgatctgcg cctggatggc cttctcggtc
    44281 ctggagtcga gtgccgaggt ggcctcgtcg aagatcagga tggccgggtt cttgagcagc
    44341 gcgcgcgcga tcgcgacgcg ctgcttctcg ccccccgaca gcttcagtcc gcgctcgccg
    44401 acacgggtct cgtagccttc gggcagctgg cggatgaagt cctccagctg cgccgcgcgc
    44461 gtggcggcct cgacctcctc gcggctggcg ttcgggcggc cgtagtggat gttgtagtac
    44521 aagctgtcgt tgaacagcac ggtgtcctgc gggacgatgc cgatcgccgc gcgcaggctg
    44581 tcctgggtga ggctgcgcag gtcgtggccg tcgatgcgga tcgcgccgcc ctgcacgtcg
    44641 tagaagcggt acagcaggcg ggcgagcgtg gacttgcccg agccggagtg gccgaccacc
    44701 gccaccgtgc tgccggcggg gatgtcgaaa tccacgtcga agaggatcgg gcgcttggcg
    44761 tcgtaggcga agctcacgtt ctcgaagcgc acgctcgccg ggccggtggg cagcgtatgg
    44821 gcgtcgggcg cgtcggcgat ctcgcggtgg gtgtgcatga ggccgaacat gcgctcgatg
    44881 tcggtgagcg actggcggat ctcgcggtag agcacgccga gaaagttgag cgggatgtag
    44941 agctggatca tgaaggcgtt gaccagcacg atgtcgccga tcgtcatctc gccgctcgcc
    45001 acccggcccg ctgcctgcca catcatcgcc gtcaccgcga ccgcgatgat cgccgcctgg
    45061 ccgacgttga gcgccgacag cgagtactgg ttggtcacct gcgccttggt ccacttctgc
    45121 aattgctcgt cgtagcgccg cgcctcgaac tcctcgttgt tgaagtactt gacggtctcg
    45181 tagttgatca ggctgtcgat cgcgcgcgcg ttggcggcgg agtcgagctc gttggcctcg
    45241 cgccgcagcg cggtgcgcca gttcgtcacc ttgacggtga acacgatgta gatcgtcagc
    45301 gcgcagagcg tgatgagcgc gaagaccgcg tcgtagttcg cgagcaggat gccgatcacc
    45361 atgccgatct cgatcagcgt gggcaggatc gaatacagcg tgtagctgat cagcgagccg
    45421 atcgagcgcg tgccgcgctc gatgtcgcgg gtgagcccgc cggtctggcg ttcgaggtgg
    45481 aagcgcagcg acagcgcgtg caggtggcgg aaaacgcgca gcgagatctc gcgcacggcc
    45541 tgctgggtca cgcgcgcgaa caccacttcg cgcagctcgg tgagcagcga ggtcgagaag
    45601 cgcagcgcgc cgtaggccag cagcagcgcc gccggcacca cgatgaaggc ctgctcgggc
    45661 gtgatcgtga ggccgtcgat caggtgcttg aagatgatcg gcaccgacac gttggcgccc
    45721 ttggccgcca ccaggcaggc gagcgcgaac agcacgcggc ccttgtaggc ccagatgaag
    45781 gggaacaggc tcttgagcgt ctgccagtcg tggcgctcgc cggtggtggg ggcggggagg
    45841 gcggcggagg gggcgcgtct catcgtaagt ctgccggtgc gtggagggcg cccgattctg
    45901 ttgcgcgccc tcccacgagt caaacggcac gaaatgggat cagctcggct tgacacgcga
    45961 taaagaaaac gtatgattca aacaaacgtt tgaaacatgc cgagtccgat gacctcgacc
    46021 ccgcccgcgc cgatcagcga cacccgtgac cgcatcctcg atgcggccga gcgcctgttc
    46081 gtggagcacg gcttcgacgg cacctcgatg cgcatgatca ccggagcggc gagcgcgaac
    46141 ctcgccgcgg tcaattacca cttcggcggc aaggacgcgc tggtacagga ggtcttccgc
    46201 cgccgcctca ccgcgctcaa tcagcgccgc ctcgcgacgc tcgatcgcct ggaggccgag
    46261 gccgccggcg cgccgctcaa gcccagccgc atcgtcgagg ccttcttcgg caccgcgctg
    46321 gagcttgctg ccgataccga gcacggcggg cgcaccttca tgcgcctgct cgcgcgcacc
    46381 tacaacgaac ccaacgcctt cgtgcgccag ttcctcgccg aggaatacgc cgaggtgatg
    46441 gaccgcttcc tcggcgcgct cttccgcgcc ctgcccgagg tgccacggac cgagatcctg
    46501 tggcgcttcc atttcatgac cggcgcgatg gcttttgcga tcgccgggcc cggtgggctg
    46561 agcgagctct tcgaggccgc gcccgacgat ggcgatcccg cccggctgct gccgcggctc
    46621 atgagcttcc tgctcggcgg gctgcgcgcg cccctgcccg acggtggtcc gcaagcctga
    46681 cgacgatttg gttcgggtcg ccctccggcg ttccgacaag aggagatgaa gatgatgacc
    46741 tggattctgc tgctttccct ccctcccttg gcaggtgcgc tcgcctacgg gcgagcgcca
    46801 ctttttgcct ggctcggggc gggtctggcg tggttgctgg cgatgggcat cgccgccggc
    46861 tggggcttct ggctgacgct gctcgcgatg gcggtgttcg ccggcgtgat gagcgtcttc
    46921 ctaatcgact cgctgcgcat gaagcacctg acctcgcgca tcttcggcgc cttccgcgcc
    46981 acgctgccca ccatgtcgca gaccgagaag gacgccctcg aggccggcac ggtgtggtgg
    47041 gaaggcgagc tcttcgccgg caggcccgac tggaaaaagc tgcaggccta tccctggccg
    47101 cagctgagcg ccgaggagcg ggccttcctg gacaacgaga ccgacgagct ctgccgcctg
    47161 acccgggact gggaatgcac ccagcacggc gacatgcccg ccgaggtctg gcagtacatc
    47221 aaggccaagg gcttcctcgg catgatcatt cccaaggagt acggcggcaa gggcttctcg
    47281 gcctacgccc actcccaggt cgtcaccaag ctgtccacgc gctcctccgc ccccgcggtc
    47341 accgtgatgg tgcccaactc gctcggcccc gccgagttgc tgctgcacta cggcacgccc
    47401 gagcagaagc agcactacct gccgcgcctg gccaccggcg aggagatccc ggcctttgca
    47461 cttacaagcc cgtgggcggg ctcggacgcc gcctccatcc ccgacgccgg cgtcgtgtgc
    47521 aagggcgagt ggcagggcga ggaagtgctc ggcatgcggg tcaccttcga caagcgctac
    47581 atcaccctcg cgccggtgtg caccgtgttc ggcctcgcct tccatctcta cgacccggat
    47641 cgcctgctcg gtggcgacga ggtcctcggc atcacctgcg cgctgatccc gcacgaccac
    47701 ccgggcgtcg acatcggccg ccgccacttc ccgctcaacg cggtgtggat gaacggtccg
    47761 gtgcgcggca aggacgtgtt cgtgccgctc gagttcatca tcggcgggcc gaagatggcc
    47821 ggccagggct ggcgcatgct catggagtgc ctggcggccg ggcgcagcat ctcgctgccc
    47881 ggctccaaca ccggcatgca gaagatggtc gcgcgcgccg tcggtgccta tgcccgcgtg
    47941 cgctaccagt tcaagaccgc gatcggccgc ttcgagggcg tggaagaggc gctcacccgc
    48001 atcggcgcca acacctatct gagcgacgcc gcgcgcgtga tgaccgccgg cgcgatcgac
    48061 ctcggcgaga agccctcggt ggtgtcggcg atcgtgaagt accacgtcac cgagcgcgcc
    48121 cgccagacgg tcaacgacgg catggacgtg atcggcggca agggcatctg cctcggcccg
    48181 cagaacttcc tcggccgcgc ctaccagcag atcccggtcg gcatcaccgt cgaaggcgcc
    48241 aacatcctca cccgcagcct gatcctgttc ggccagggcg cgatccgctg ccatccctac
    48301 gtgctcgccg agatgcactc ggcgcagaag agcgacctga aggccttcga caaggcgctg
    48361 tggggccacg tcggcttcac cgtgtcgaac gccgcgcgtg cgctgatcat gggcctgacc
    48421 gggtcgcact tcgtcaaggt ccccggcgac gtcgcgccgg agacgcggcg ctactaccag
    48481 cagctcaccc gcttctcggc cgccttcgcc ttcatcgccg acatttccat gggcaccatg
    48541 ggtggcgccc tcaagcgcaa ggagaagctc tccgcgcgcc tgggcgacat cctgtcgctg
    48601 atgtacctgg ccaccgccac gctcaagcgc ttcgaggccg aaggccgcca cagcgccgac
    48661 gcgccgctga tgcactgggc gatctgggac tgcatgttcc gcatccagca ggccttcgag
    48721 ggcgtgatcg cgaacttccc caacaagctc ttcgccttcg tgctgcgccg cgtcgtggtg
    48781 ttcccgctcg gtcgccccta tgtcgtgccc tcggacaagc tcggccacaa ggtcgccgcg
    48841 ctgctgctcg aaccctctcc gacgcgcgac cgcctgaccg cggacgtgca tcttcccacc
    48901 gacatcgagg acccggtcgg cgcgctcgag gccgcgctcg ccgcgacgct ggccgccgag
    48961 ccggtcgagg ccaagctcaa ggacgcacgt cgccaggggc gcttcgatcc gaagaacctc
    49021 gcctccggcg atgtggacga gatctggcgc gtggccctgc acgccggcgt gatcgacgag
    49081 cgcgagttcg cgctggtcga gcgccgcaat cagctccgta acaaggtgat ccgcgtggat
    49141 gacttcccct acgacctcga cctcaaggcc gccgtccagg ccatgcccga gcgctcgccg
    49201 gcgcagcagg tgagcgcatg aacgcgagcg caaggcattc cgcgggcaag cacgcgcatc
    49261 ccgcggggaa gaaggaggcg agtccggcaa acaagccgat ctacatcgtc gatggcgcgc
    49321 gcacgccctt cctgaaggcg aagaacgcgc ccggcccctt caccgcttcc gacctcgcca
    49381 ccgctgcggg cagcgcgctg ctgatgcgcc agcccttcgc gccggaccag ctcgatgagg
    49441 tcatcctcgg ctgcgccagc ccctcgccag acgaggtcaa catcggccgg gtggtcgcgc
    49501 tgcgcctcgg ttgcggcaac caggttcccg gctggacggt gatgcgcaac tgcgcctcgg
    49561 gcatgcaggc gatcgattcg gcgatcgcca acatccagtg cggacgcagc cagctcgtgc
    49621 tcgccggcgg cgtcgatgcg ctctcgcacg cgccgctgct gttctccgag aagatggtgc
    49681 gctggctcgc cggctggtat gcggcgcgca gcaccggcga ccggttggcg atgctgaaga
    49741 ccttccgcct cggccacctc gccccggtga tcggcatcat gaagggcctc accgacccga
    49801 tcgtcggcca gctgatgggc cagaccgccg agaacctggc gtggaagttc ggcatcacgc
    49861 gcgcggacat ggacgccttc gcggtcgaga gccaccgccg cgtgtgcgcc gggcaggacg
    49921 ccgggcacta cgccaacgag atcgtcccgc tgatcgaccg cgacggcgag gtccatgcgg
    49981 ccgacgacgg cgtgcggcgc gactcctcga tggccaacct cgccaagctc aagcccttct
    50041 tcgacaggaa atacggccgc gtcaccccgg gcaacagctc tcagattacc gacggcgcgg
    50101 cctggctggt gctggccacg gaagaggcgg tcgggcgtca tggcctgaag ccgctcggac
    50161 gcatcgtcga cagccagtgg gcggcgctcg cgcccgacca gatggggctc gggccggtgc
    50221 acgcctcgat gccgatcctg cagcgccatg gcctcgcacc caacgacctc gacgcctggg
    50281 agctcaacga ggccttcgcc gcgcaggtca tcgcctgtct gcgtgccttc ggggatcacg
    50341 actactgccg cacgcacttc ggcgtggatg cgccgggcgc gcccgatgcc gggcggctca
    50401 atgtggatgg cggcgcggtc gcgctcggcc acccggtcgg cgcgagcggt gcgcgcatcg
    50461 tgctgcatct gctcgaggtg ctgcgccgca agggcggcgg gcgcggcctg gcgaccatct
    50521 gcatcggcgg cgggcagggc ggggcgatgc tggtggagac ggtgtgatga gcgcgaacat
    50581 gcaacaagac tggaagcact ggcgcctgcg ccgtgaagac accggcctgg cctggctgga
    50641 gctggacaag gcggacgcga gcgcgaacgt gctgtcgtcc gaggtgatga gcgaattcgc
    50701 ccgcgtgctc gacgcgctcg acgccgcgcc gcccaaggcg ctggtgatcg cctcggccaa
    50761 gccggccggc ttcatcgccg gcgccgacat cgaggagttc tcgcggctgg attcggtgct
    50821 cgccgcgcgc atgctggtcg agcgtggctg gctgctgttc aagcgcctcg ccgcgctgtc
    50881 ctacccgacg ctggcgctga tccgcggcca ctgcatgggc ggcggcctgg agctcgcgct
    50941 cgcctgccgt caccgcctcg tggtcgacga gccgggtacg aagctcgcgc tccccgaggt
    51001 catgctcggc atcgtccccg gctggggcgg catgctgcgc ctaccagcgc tcatcggccc
    51061 ggcggcggcg ctcgacctga tgctgaccgg caagagcgtc gatgcgaaga aggcgaagcg
    51121 cctcggcttg gccgacgact gcgtgccggc gcgggtcatg gagtcggccg cacgcatcgt
    51181 ggcgctcggc ggcaagcccg cccgacaact gccggcgaag gagcgcgcca cgcgctgggc
    51241 gatgaacggc ccgctgcgca ggatggtcgc cgacaaggcg cgcgcccagg ccgcacgcaa
    51301 ggtcagccgc gccaactacc cggcgccgtt cgcgatcgtc gacatctggg aaaaatacgg
    51361 cggcaacgcg ctcgacgtgc cggccagcga cccgtcctcg ctcgacagca tcttcacctc
    51421 gcccaccgcg cgcaacctgg tgcgcgtctt ccacctgcag gagcgcctca aggccttcgg
    51481 caaggacagc gacttcgcgc cgcgccacgt gcatgtggtg ggcgccggcg tgatgggcgg
    51541 cgacatcgcc gcggtgtgtg cgctgcgcgg catgacggtg acgctgcagg accagtcggt
    51601 cgagcgcatc gcccccgcca tcgcccgcgc aaccaagctc ttcgagcgcc gccacaaggg
    51661 cgaccagaag caggtacgct tcaccctcga ccgcctgatc cccgacccca agggcgaggg
    51721 cgccgccagc gccgacctga tcatcgaggc gatcttcgag aacctggagg ccaagcgcag
    51781 cctgttcgcg gacctcgagg cacgtgccaa acccgacgcg gtgctcgcca ccaacacctc
    51841 cagcctgcgc ctggaagaca tcgccagcgc gctgaaggcc cctgcgcgcc tggtcggcat
    51901 ccacttcttc aacccggtgc cgatgctgcc gctggtcgag gtggtgcagg gtgaggccac
    51961 cgacgccgag gtgctgcgcc gcgccaccgg cttcgtgcgc cgcatcgaca agctgccgct
    52021 gccggtgcag agcgcgcccg gcttcctggt caatgccgtg ctcggcccct acatgctcga
    52081 ggcgctgcgc tgcgtcgagg aaggcgtcgc gcccgcgacg gtggatgccg ctctgatcca
    52141 gttcggcatg ccgatgggac cggtcgagct ggtcgacacc gtgggcctgg acatcgccgt
    52201 ggccgctggc aaggcgctgg cgggcgaagg cgtggagccg cccgcgcggc tgctgaagct
    52261 ggtggccgag ggcaagctgg ggcgcaagag cggcgagggt tactaccgct gggtcgaggg
    52321 caaggcgctc aagggcgcag acaaggaggc tgcgccggag gggctgctcg cccggttgct
    52381 gagccagctg ccgggcaggc gccggccgga cccagctccg ccgattccgc ccggcctcgc
    52441 cgagcgcgtg ctcgcgccgc tgctggcggc cacgcggcgc tgcgtggcgc agggcgtggt
    52501 ggccgacgcg gatctggccg atgccggcgt gatcttcggc acgggcttcg caccgcacac
    52561 gggcggtccg ctgacctatt gcagaagcaa gggaaaaccc gactagaaac cccgctgcga
    52621 ggtggcggat ggtgcgcaca gcataggtga atcgcatgaa cggctacgct gctgcgagag
    52681 agggcgaccg cagcgtggaa tgaaggatgg tttgcagcaa tcagtcgcac cccccagggc
    52741 gccggggtgc ggcttccagt accaggtgcc aggcacgcca ccgggagaaa cccggggctt
    52801 ttttgatcga agtgaggaga cccgaaatgc agaaaaccct gatcgcccgc gtgctgcctg
    52861 cagcactgct cgcacttgcc agcggcaccg cctcggcagc cggcttccag ttgctggagc
    52921 agaatgccag cggcatcggt aacgcctacg ccggctcggc cgcggtggcc gagaacgcca
    52981 gcacgatctt cttcaacccg gccggcatga cgcagttgca ggcgcgcgag gtgtcggcgg
    53041 gcttgtcgct ggtgcggccg agcttcaagt tcacaaacca gggttccatt cccgccggcc
    53101 cctcttccgc gcaggacgca ggggattggg ccgcgctgcc gaatgcctac ctgtcgtggg
    53161 cgctgaacaa ggacctctac gtcggggttg gcatgggcgc gccgttcggc ctcgtgacgg
    53221 agtacaaccg cgactgggtt gggtcggcgc actcgatcaa gttcgacatc aagacgatca
    53281 atatcaaccc gtcgatcgct tggcgcgtga acgagaaggt gtctatcggt tttggcctga
    53341 actggcagaa gatggacgcc gagtatgtcc gtcgtgctgg agccgttact ccccttctgg
    53401 gtcctttgag cccgctctcc tccactttcg tcacgctgaa ggctgacgac gcgtcgtggg
    53461 gttggaacgt tggagcgttg tttagcgtat cggaggctac gaaggtcggt gtgtcgtatc
    53521 gatcgaaggt gaagcatgaa ctcgagggct cgctcgcttt ctcgggcgct gcggcgcaga
    53581 accctgcgtt cggcggcacg acgacggaca gcagcgcttc cgccgacgtt gaactgcctg
    53641 acacctttat cgccagcttc gcgcacaagc tcgatccgag gtgggagctg ttgggtgacg
    53701 tttcctggac cggttggagc agcatcgaaa aggtcgacat cgttcgcacg tcgggcaatc
    53761 tggctggcac gccgctggca acggcgcaga cgctcgaaac ggatttccag gacacctggc
    53821 gtgtcgcact tggcgcgaat tatcagctca atgacgcctg gaagctgaag ttcggtgtcg
    53881 ctttcgacga gactccggtc aagaccgccg aatctcgcct gacctcgctg ccggacaatg
    53941 atcgcatctg gttctcgttc ggtggtcagt ggaaacccaa caagggttcc gcgctcgaca
    54001 tgggtgtggc ttacctgtac gtcgatgaca ccgagatcaa taacggggag gccgttgatg
    54061 ccgcccagag gaaggtgcgc ggcctcgtca agggcgaata cgactccagc gtctggattg
    54121 tcggcgcgca gtactcgatg tcgttctgat tgacgcctcg ctcacggccc gcgtcgctcc
    54181 cggcgcgggc cgtgtcgctt gcgtcctgta tttcctgcca tccggagaac cgcatgagcc
    54241 gtctcatcat ccgtaaagtc gccgtcctcg gcgccggcgt catgggggcg cagatcgctg
    54301 cccattgcgc caacgccgac gtgccggtga tcctgttcga cctgccggcc agggaaggcc
    54361 cggccaacgg cgtcgtcgac aaggcgctcg ccagcatgaa gaagctcgac cccgcgcctt
    54421 tcgccgccaa ggaccgtgcg cagtacgtcg aggctgccaa ctacggcagc gacctcgccc
    54481 gcctgggcga gtgcgacctc gtcatcgagg cgatcgccga gaagatggag tggaagctcg
    54541 acctctacgc caaggtcgcg ccgcatctga agaccggcgc gatcttcgcc tccaacactt
    54601 cgggcctgtc gatcgaggcg ctcgccgccg gcatgcccga cgatcgccgc agccagttct
    54661 gcggcatcca cttcttcaac ccgccgcgct acatgccgct ggtcgagctg atcccgaccg
    54721 cagccaccga ccccgcgctg ctcgacggcc tcgaagcctg gctgatcacc cgcctgggca
    54781 agagcatcgt gcgcgccaag gacacgccca acttcgtcgc caaccgcgtc ggcgtgttct
    54841 ccatcctagc cgtgctgcac cacaccgccc gcctcggcct ggccttcgac gaggtggacc
    54901 tgctcaccgg cccgcgcatc ggtcgcccca agagcgcgac cttccgcacc gccgacgtgg
    54961 tcggcctcga caccctggtg cacgtgctcg ccaccatgca ggcgacgctg cccgacgacc
    55021 cgtggtgcgc gcacttcacg acgccagaat ggctgcaggc cctgatcgcc aagggcgcgc
    55081 tagggcaaaa gaccaaggcc ggcatctatc gcaagcaggg caagcagatc caggtgctcg
    55141 acctgcacct gcaggactac cgcgagagcg gcggcgaggt gttgcccgag gtggaggaga
    55201 tcctcaagct ccgcaacccg gtggagaagt tcgcccagct cgccgcgcac ccgcatccgc
    55261 aggcgcagtt cctgtggtcg atcttccgcg acgtgttcca ctactgcgcg gtgcatctgg
    55321 ccgaaatcgc cgacaacgcg cgcgacatcg acctggccat gcgctggggc ttcggctggg
    55381 cgcaggggcc gttcgagacc tggcaggcgg cgggctggaa ggcggtggcc gagatggtgc
    55441 gcgacgacat tgcccacggc cgcgcgatgt ccgacgtgcc gctgccggcc tgggtgttcg
    55501 agcgcgacgg cgtgcatgcg ccggccggct cctacagcgc cgccgagaac accttgaaac
    55561 cgcgcgccgc gctgccggtg taccagcgcc agctctaccc cgaccgcgtg ctcggcgagg
    55621 cgccggacga tcgcggtgag accctgtggg agaacgccgg cgtgcgcctg tggcggcgag
    55681 ccgaccagga cgggcgcatc ggcatcgtgt cgatcacctc caagatgcac gcggtgggcg
    55741 aggaggtcat ggacggcctg ctcgaggcga tcgcgcgcgc cgagcgcgag ctcgacggcc
    55801 tggtgatttg gcagccggcg ccgtttgcgg tgggcgccaa cctgcagcag gtgggcgagg
    55861 cttgccgcgc cgggcagttc gacctgctcg agcagatggt ggccaagttc cagcgcacct
    55921 cgatgacgat caagcacgca cagattcccg tggtggctgc ggtgcagggc atggcgctgg
    55981 gcggcggctg cgagttcgtc atgcatgcgg cgcaccgcgt gttcgcgctc gagagctacg
    56041 tcggcctggt cgaggcgggc gtgggcctga tcccggcggg cggtggcagc aaggagttcg
    56101 cgctgcaggc gcacaacctg gcgcagcgtg cggcaggtgg cgacgtgttc ccgtacatcc
    56161 agaacgcctt ccagaccatc gccatggcca cggtggccaa gagcgcactc gaggccgtgc
    56221 agctcggctt cggccgcgcg ggcgacgacg tggtgttcaa cgccaacgag atcctttttg
    56281 ctgcgatcca ccgcgcgcgc gcgctggccg agtcggcctg gcggccggcg ctggtgaacc
    56341 cgcaggtcac cgtggccggc cgcaacggca tcgccacctg cgaaatgatg ctggtgaaca
    56401 tggccgaggg cggcttcatc tcggcgcacg actaccgcgt cgccaaggcc gcggccaccg
    56461 cgctgtgcgg cggcgaggtc gacaccaacc ggcgcgtgag cgagcggtgg atcctcgacg
    56521 tcgagcgcgc gcagttcgtc gagctgctca agaccgagaa gacccagcag cgcatcgcgc
    56581 acatgctcga aaccggcaag ccgctgcgca actgagggag aacgagacaa tgagcaaaca
    56641 gattcaggac gcctacatcg tcgccgcggt gcgcacgccg gtcgccaagc gcaacggcgc
    56701 cttccgcgcc gtgcgtcccg acgacatgct ggcgacggtg ctgcgcgggg tgcttgccaa
    56761 ggtgcccagc ctcgacccca gcgagatcgg cgacgtggtc accggctgcg cgatgcccga
    56821 ggccgagcag ggcatgaacg tggcgcgcat cggcctgctg ctggccggcc tgcccgatcg
    56881 tgtgccgggc atcaccatca accgcttctg cgcctccggt ctgcaggcgg tggccgacgc
    56941 cgccagccgc atccggctgg gcgaggcgga cgtgatgatt gccgccggca ccgagagcat
    57001 gagcgccttg ccgcagatca tgggcaacaa ggtcagcctc aaccccgagg tcttcgcccg
    57061 cgccgagaac gtttcgatcg cctacggcat gggcctgacc gcggagaagg tcgcgcagca
    57121 gtggaaggtg agccgcgagg accaggacgc cttcgcggtc gagtcgcacc ggcgcgcctg
    57181 cgctgcgatc gccgcaggcc atttcaagga cgagatcctg ccctacgcgg tgaagtccta
    57241 cgcgccgggc gccgatggca cggtgcgcat caccgagcgc ctggtcgagc acgacgaggg
    57301 cccgcgcccg gacgccgctg ccgacaagct cggcaagctg cgcccggtgt tcgccgcgcg
    57361 tggctcggtg accgcgggca acagctcgca gatgtccgat ggcgccgcgg cggtgctgct
    57421 gatgagcgag gcggcggtca ggcgctacga cgtcaagccg atcgcgcgct ttgccagctt
    57481 cgcggtcgcc ggtgtgccgc ccgaggtcat ggggatcggc ccggtcgagg ccatcccgcg
    57541 tgctctgacg cgcgccgggg tggcgatggc cgacctcggc tggaccgagc tcaacgaggc
    57601 cttcgccgcg caggcactgg cggtgatgcg ccagctcgag atggacccgg cgaaggtcaa
    57661 cccgctcggt ggtgcgatcg cgctcggcca tccgctgggc gcgaccggcg cgatccgcac
    57721 cgccacgctg atggcggcga tgcaacgcga ccccggcctg cgctacggca tgatcagcat
    57781 gtgcatcggt accggcatgg gcgcggcggg agtgttcgag cgcgtctgat gttgcggtgc
    57841 acgactaatc ctgagtgctg acttgcgaag ggcttgatga aagccgtcgg ggcccgaggt
    57901 gggctccggc ggcttcggtg cttccggatg ctgttgtgca gcatgagaat ggaattgatt
    57961 tttctgcgct tggcgggcct ttcgcgcatt gtggattgta cgaatacggg gagttcctga
    58021 tgcctgcggg cgtgatcggg cggtaacaat cttttataat ccgggcgttt atcgacgcgg
    58081 gatcgccccg gcgtccgggc gcctggtggt tccggatgtg cgtacggcgg cccgtgcctc
    58141 cagtggaatc aacgggcgag aagcgcatga tcagaatcaa acgcggtctg gacctgccca
    58201 tcaccggcgc tcccgagcag cgcatcgagg ccggcaggcc ggtgcgcagc gtggccgtca
    58261 tcggcttcga ccatcacggc atgaagccga ccatggcggt gcaggtcggc gaccgggtga
    58321 agctcggcca ggtcctgttc tccgacaaga agaccccggg cgtggtgtat accgcgcccg
    58381 gtgccggcac ggtcagtgcc atccaccgcg gcgagcagcg cgtgctgcag tcggtggtga
    58441 tcgacctcga tggcgatgac gcgatcgagt tcaggcgctg cacggacgcc gagatcgacc
    58501 ggctcgacga cccgacggtg cgcagcaatc tgatcgactc cggcctgtgg accgcgctgc
    58561 gcgcacgtcc cttcggcaag gtgccggcga tcgacgccaa gccgcactcg atcttcgtca
    58621 ccgcgatcga cacccacccg ctcgccgccg acccgaccgt ggtgatctcc gagcataagg
    58681 acgacttcgc ccgcggcgtg cgcgtgctcg cccgcatcgc gccggtcgtc gtttgtcacg
    58741 ccgacggcac ccagatgccc tgctcggggc tcgccgacgt gcgcaccgag accttcgccg
    58801 gtccccaccc ggccggcctc gccggcaccc acatccactt cctcgacccg gtgcatgcag
    58861 agaagtcggt gtggtcgctc aactaccagg acacgatcgc ggtcggcaag ctcttcgcga
    58921 ccggccgcct gtggaccgag cgcgtggtgt cgatcgccgg cccgatggcc gcgaagccgc
    58981 gcctcgtgcg cacccgcctc ggcgccagcc tcgacgagct gaccgccggc gagctcaaga
    59041 ccggcaagaa gctgcgggtg atctccggct cggtcttcgg cgggcgcacc tcgcgcggcg
    59101 cctgcgcctt tcttggccgc taccacctgc aggtgtcctg cctggaggag ggcaccgagc
    59161 gcgagatgct gcactacctg cgcgcggggg cgaacaagca ctcggtgatg aacctgttta
    59221 tctccaagct ctcgtcgggc aagctcttcg atttcaccac ctccaccaac ggctcgccgc
    59281 gcgcgatggt gccgatcggg aactacgagg aggtcatgcc gctcgacatc ctgcccacgc
    59341 agctgctgcg ggcgctgatc gtcggcgaca ccgagatggc gcagaagctc ggctgcctcg
    59401 agctcgacga ggaagatctc gccctatgca cctatgtgtg cgcgggcaag tacgaatacg
    59461 gtcccatcct gcgggacaac ctgacccgca tcgagaagga gggttgagca tgagtctgcg
    59521 ctcctggctc gacagcatcg agcatcattt tgaaaagggc ggcaagtacg agaagttcta
    59581 cgccctgtac gaggccgtgg acacggccct gtacaagccg cccctggtca cccgcaacac
    59641 cgcccacgtg cgcgacggtc tcgacctcaa gcgcatgatg atcacggtct ggctgtgcac
    59701 cttcccggcc atgttcttcg gcatgtggaa cgtcggctac caggccaaca ccatcctcgc
    59761 cggcagtccg gagctgatgg ccgcgcagga gggctggcgc atcgcgctca ccggcgcgct
    59821 ggccgggctc gatcccgcca gcctgtgggc caacttcgtg cacggggcga cctacttcct
    59881 gccgatctac ctgacgacct tcatcgtcgg cggcttctgg gaggtgctgt tcgcgtcgat
    59941 ccgcaatcac gaggtcaacg agggcttctt cgtcacctcg gtgctgttcg ccctcaccct
    60001 gccgcccgac accccgctct ggcaggtggc gctcggcatc agcttcggcg tggtgatcgc
    60061 gaaggaggtc ttcggcggca ccggcaagaa cttcctcaac cccgcgctcg ccggccgcgc
    60121 cttcctctac ttcgcctatc cggccgagat gtcgggcgac gccgtgtgga ccgcggtgga
    60181 cggctacacc ggcgccacca tgctgtcgct cggcgccgcc ggcggtatcg aggcggtggc
    60241 cggcgccggc atcgactgga tgagcgcctt cctcggcacg gtgcacggtt cgatcggcga
    60301 gaccagcacg ctcgccatcc tgatcggcgg cgcggtgctg ctggtcatga agatcgcctc
    60361 gtggcgcatc gtctccggcg tgttcctcgg catggtggcc tccagcctgc tcttcaatgc
    60421 gatcggctcc gacaccaacc cgatgttcgc cgtgccctgg cactggcacc tggtgatggg
    60481 cggcttcgcg ttcggcatga tgttcatggc caccgacccg gtgtcggcct cgatgaccaa
    60541 caccggcaag tggatcttcg gtgccgtggt cggggtgatg accgtgctcg tgcgggtggt
    60601 gaacccggcc ttccccgagg gcatcatgct cgccatcctg ttcggcaacc tttgtgcgcc
    60661 gctgatcgac cacttcgtgg tcgcggccaa catcaagcgg aggctcgcgc gcaatgtcca
    60721 ctaaggaatc gacgacccgc acgctgatgg tggcgctcgc ggtcagtctc gtcagctcgg
    60781 tcttcgtcgc cggcgcggcg gtctcgctca agccggtgca gatcgagaac cgccagctcg
    60841 acaagcagcg cagcatcctg tccattgccg gtctcggcgg cgacggcatg tccgctcgcg
    60901 aggtcaagga tctcttcgcc agccgcattc aggcgcgcgt ggtcgatctc gagaccggcg
    60961 cctacaccga cgcccacgac ccggccgtat tcgacccgct caaggcggcg cgcgacccca
    61021 agctctccga cgcgctcgcc ggcgaggagg acatcgcgct gatcaagcgg cgcgagcgct
    61081 tcaccacggt ctatatggtc gagaaggacg gcaagctcga atcgctgatc ctgccgatcc
    61141 gcggctacgg cctgtggtcc acgctgcacg gcttcatggc ggtgaagggc gacctcaaca
    61201 ccgtggtcgg catgggcttc taccagcacg ccgagacccc gggcctcggc ggcgaggtcg
    61261 acaacccgaa ctggaagggc ctgtggccgg gcaagcagct cttcgacgag caggggaagc
    61321 cggtgatccg catcgtcaag ggcggcgtcg atccggccag cccggaggcg aagcaccagg
    61381 tcgacgcgct cgccggcgca accctgacca gcaacggcgt cgaccgtctg atccagttct
    61441 ggctcggcga gcagggcttc ggcccctatc tcgccaaact gcgtagcaag ggggtctgat
    61501 catggccaag cccaccgtca aggaagtcct gttcaatccg gtcttcgcca acaacccgat
    61561 cggcctgcag atcctcggca tctgctcggc gctcgcggtc acgtcgaatc tgcagaccgc
    61621 actggtgatg tcgctcgcgc tgacgctggt gaccggtttc tccaacctgt tcatctcgat
    61681 gatccgcaac cagatcccga gctcgatccg catgatcgtg cagatggtga tcatcgcctc
    61741 gctggtcatc gtggtggacc agatcctcaa ggcctacgcc tacggcctgt cgaagcagct
    61801 ctcggtgttc gtcggcctga tcatcaccaa ctgcatcgtg atgggccgcg ccgaagcctt
    61861 cgcgatgcag aacccgcccg tgctgtcgtt ctgggacggt atcggcaacg gcctgggcta
    61921 cagcgtggtg ctgctcaccc tcggcgtgat ccgcgagctc ttcggcgccg gcaagctctt
    61981 cggcgtcgag atcatcgcgc tcgccaagga cggcggctgg tacgtgccca acggcctgct
    62041 gctgctgccg ccctcggcct tcttcctgat cggcctgctg atctgggcgc tgcgcacctg
    62101 gcgcaaggag caggtcgaga agcccgcctt ccggatggcg ccgcaggtcg tggaaaagga
    62161 ggcctactga aatggaacac tatctgagcc tcttcgtgcg ggccgtgttc atcgagaaca
    62221 tggcgctcgc cttcttcctc ggcatgtgca ccttcatcgc gatctcgaag aaggtcgaga
    62281 ccgcgatcgg cctcggcatc gcggtgatcg tggtgcagac tatcacggtg ccggccaaca
    62341 acctgatcta cacctacctg ctgcgcgaag gcgcgctggc gtgggcgggg ctgcctgacg
    62401 tcgacctgtc cttcctcggg ctgctgtcct acatcggcgt gatcgcggcg atcgtgcaga
    62461 tcctcgagat gctgctcgac aagtacgtgc ccagcctcta caacgcgctc ggcgtcttcc
    62521 tgccgctgat cacggtgaac tgcgcgatca tggccggctc gctgttcatg gtggagcgcg
    62581 actacaacct cgccgagagc acggtgtacg gcatcggctc gggcgcctcg tgggcgctgg
    62641 cgatcgcgct gctcgccggc atccgcgaga agctcaagta cagcgacgtg cccgagggcc
    62701 tgcagggcct cggcatcacc ttcatcacca tcggcctgat gtcgctcggc ttcatgtcgt
    62761 tctctggcgt gcagctctaa ggagaccgtg aaacgatgaa taccgaaatc atcctcggca
    62821 tcgggatgtt caccgccatc gtgctcgcgc tggccgtgtt catcatcgct gcccgctcca
    62881 agctggtgtc gtcgggcgac gtcaccatcg acatcaacgg cgagaagaag atcaccgtgc
    62941 ccgccggcgg caagctgctg cagaccctgg ccgagaccgg cctgttcctg ccctcggcct
    63001 gcggtggcgg tggcacctgc gcgcagtgca agtgcatcgt caaggagggc ggcggttcga
    63061 tgctgccgac cgaggagtcc cacttcacca agcgcgacgc caaggaaggc tggcgcctgt
    63121 cctgccagac gccggtcaag caggacatga aggtcgaggt cccggaggag gtcttcggcg
    63181 tcaagcgctg ggaatgcacc gtcgagtcca accccaacgt cgccaccttc atcaaggagc
    63241 tcaccctgcg cctgcccgag ggcgaggacg tgcatttccg cgccggtggc tacgtgcagc
    63301 tcgagtgccc gccgcacgtg gtcaattaca aggacttcga catccaggac gagtaccgcg
    63361 gcgactggga caagttcaac ctgtggcgct acgtctccaa ggtcgacgag accaccatcc
    63421 gcgcctactc gatggcgaac taccccgacg agaagggcgt ggtgaagttc aacatccgcg
    63481 tcgcctcgcc cccgccgggt cgcgacgaca tcccgccggg caagatgtcg tcctgggtgt
    63541 tcaacctcaa gaagggcgac aaggtcacgg tgtacggccc cttcggcgaa ttcttcgcgc
    63601 gcgagaccga tcacgagatg gtcttcgtcg gcggcggtgc gggcatggca ccgatgcgct
    63661 cgcacatctt cgaccagctc aagcgtctgc acagcacgcg caagatcagc ttctggtacg
    63721 gcgcacgctc gatgcgcgag gccttctacg tcgaggaatt cgacaagctc gccgccgaga
    63781 accccaactt caagtggcac ctcgcgctct ccgacccgct gcccgaggac aactggaccg
    63841 gctataccgg tttcatccac aacgtgctgt acgagaacta cctcaaggac cacccggccc
    63901 ccgaggactg cgagttctac atgtgcggcc ccccgatgat gaacgccgcg gtgatcaaga
    63961 cgctgctcga cctcggcgtc gagcgcgaga acatcatgct cgacgacttc ggcggctgaa
    64021 cactgccgca tccgcatccg catccgcatc cgcgaccgca tgcgcccgcg cagccgcctc
    64081 acgaggcggg cgcgggcttt ttcatggctg cgctgcgcat tggtgaagcg ctgcgggtcg
    64141 gcagcgctgc cggcccctcc cgacgtgctc cggtggcgct cagcgcgacc agcgataggc
    64201 gagctggccg aacagctcgt ggagcgcgaa ccaggccgcg taggcggtgt tctggctcgg
    64261 cgccaggggc agggcctggg cctcggccgg cgtgtcgccg ccgcccagcc aggcggtcgg
    64321 cgccgggacc acgtcgaggc cggccgcttc gaactcggtg cgcgcgcggt cgatgtgcat
    64381 cgcgtgggtc accagcagga tccttttcac gccggccgcc tgcaggtgca ccgccgagaa
    64441 gcgcgcgttc tcgcgcgtgt cgcgcgaggc cgtctccacc cagcgcggcg gcaggccgta
    64501 ctcgtcgcgc agcagcgccg ccatgaggtt cgcctcgggg gtgtcgccgg cgggtgcgcc
    64561 gccgctcacc agcagtggca gacgggtctc gcgggcgagc gcggcggcgt agcgcaggcg
    64621 ctcgagcgcg agccggttga ccgtctcgcc accgaactcg ggcgcgtgcg tgcgcttgcc
    64681 ggcgccgagc accacgatcg cctgcgcctc gcgcagccgc gcgcgatcga gcgtgtgcgg
    64741 gtactcgacc tgcgctacca gccagcccac gctcggcggc atgatcagca ggaggttcag
    64801 cgccacgcct ccccaggcga gcgcgcgccc gaggcggggc cggcggcgca gcgccaacag
    64861 gccgagcacg atcggcagca gcggcagcac gggtggcagc gcgagcactg cgacgagctt
    64921 cttgagccag aagaggaggg tgtcgggggc gagttccatt tgcgggcagg gcggggtttg
    64981 gcggcggctg ccgcggccaa gtattatcga cgcatcccgc cttcgctacc ctaatgcctc
    65041 ctagcctgaa tctcctccac ttgccgcgag atcgttcccg atgcccgggg ctgaatcgca
    65101 cctcgccggg gatcgtcctc catgcgtgag gccatgttgt ggctggctgc gctcctggcg
    65161 gcgtatgcga ccttcgagtt cctgcgtgcg ctgcggctgc cgcgcgaagg tgcggccggg
    65221 gctttcgtcg caccgcagtc cgctgccgca ccgcccgcaa cggtcgtcgc ggccagagat
    65281 gaccgggacg acgaggacga cgacttcctc gcctacgcgc cgctgccttc ttcggcttcc
    65341 cccgccgcgg gcgcggctgc ggccggcccc gcgcctttcc cttccgactc tgccgccgcg
    65401 gccgaagcgg ccgcggcggc acgcttcgag ctcgaactcg agaactcccg ccttcgccag
    65461 gcccttcagg cacagcgcga cctggtggcg ctgcagcaga gcgagatcga tcgtctcgtg
    65521 gaggacatca ctgccctgcg tgaggagctc gacgcccacg ccgcgtccgt cgccagctcg
    65581 cccgaatatt ccgaggcgat ggtgcttgcc gcgcaggggc tcaacgccga gatgatcgcc
    65641 gagcgctgcg gcatcaccct cgccgaggcc gagctggtcc tcgcgctcgg gcgcgatgga
    65701 gaagggcgtc gatgaagctg ccgcgtttcc ctgcgacccg atcctcgctt ccgcccggct
    65761 cgccgcgccg cgccgcactg gtccgcgcgg ctgcggcgct ctccgccgcg ctcgtgctgc
    65821 tggtgctcgg cctgctcgat cgcgatcgag ccgcgccgcc gcgcccgggg ggcgaatccg
    65881 tcggcgcggc gccacccggg gcgcccgtcg ccacttcccc gagcttgccg ccgggcgcga
    65941 cttcgccgcg ggcggccggc aagctcggca gcgccgcggc ggcgcccggg gtcgagaccg
    66001 catccggggc cgtcggcctg gcggaggtcg cggcgcccac ctcatcctgt ccggcccccc
    66061 caccggcccc ggcctgcccg ccgcctcccg cgccgaccgc acagggcgac ggcatcctgc
    66121 tgccgcgcgc tgcagcggcg cccgccggcc ccggctacct cgtccagctc ggcgtcttcg
    66181 ccgcccccga caatgcgctg cgtgtctatc ggcaggctgc cgccgccgga cagccggccc
    66241 acatccagag ccgcgtcgtc ctcggcccct ttgccgaccg cgaatccgcc gaacgcgccc
    66301 gcaagcgcct gcaggcggcg ggcgccgggc ccggcgtgct gattcccccg caacgcccgc
    66361 gttgagcgga cgtgaagccc gtcacggcgc gcaggtcgtg tatcggatga tgatgttttt
    66421 ttgaagcgag gttcccctca tgcagatcaa gagtccgctg ttcggcagcg ccgagatttc
    66481 cgaagacaag atcatcgagt ttcccagggg cctgccaggc ttcgagcact gccgccgctt
    66541 cactctgctg cacgaggaag ggcgcgaggc gcatgtgttc gtgctgcaga gcgtggacga
    66601 gcccgacgtc gcgttctcgg tgaccgcgcc cgagcgcctc ggcgtccatc tggagtttcc
    66661 gctggatgac caggaggtcg cgctgctgcg cctgcacgcg cccgaggatg ccgcggtggc
    66721 ggtgatcgtg cgcaaggacg acggcgaagg cccggccgga accggtctgc gcgccaactt
    66781 catggcgccg ctggtgatca acaccggcgc acgcgtcggc ctgcagaaag tcatcgaccg
    66841 cctcggctgc gagatcacgc tgcgcgcggg cggctgatcc gcatcggggg tgtgcgggcg
    66901 gcatgtccgc ctgcggccgc gggtacaatg ctcgctttcc ccaagcagag tcaggatcat
    66961 ggcccgtcag atcatctcca cccccaatgc ccccgccgcc atcggcccct actcgcaggc
    67021 cgtcaaggtc ggcaatcagg tcttcctctc cggccagatc ggcctggacc ccgccaccat
    67081 ggaaatggtc gagggcgtcg aggcgcaggc ccggcgcgtg ttcgacaacc tcgccgcggt
    67141 ggccgaggcc gccggcggct ccttcgccga cgtggtcaag atcaccatct acctcaccga
    67201 cctggccaac ttcggcgtgg tcaacgagat catgaagtcc tgcttcgccg agccctatcc
    67261 ggcgcgtgcc accgtcggcg tgcgcgagct gccgcgcggt gcgctggtcg aggcggatct
    67321 ggtgttggtg atcgagtgag gcgtgaggtt taaggcttaa ggtgtgaggc gcgaggggcg
    67381 tggcgctcga cgcgctgcgt ccctggtgcg ctgactcgat gtgccggtcg cgtgccggtc
    67441 ggcgagcggc ggacatgcgc gctcgctcgc ctctttcctc ctcgcgagaa ggatccacga
    67501 ttgaacgcga tgcagccgcc gcgcggctgg ccgggggtcg gggcgcagtt ggcggggcga
    67561 cttgcgaagc tcgacctgcg cgcgccgcgc gatctcctgc tgcacctgcc gctgcgctat
    67621 gaggacgaga cccggctgac gccgatcgcc caggtgcgcc ccgggtttcc cgcccaggtc
    67681 gagggcgagg tgacgagcgc cgaggtcgtg ctgcgtccgc gccgccagct cgtggcgcgg
    67741 atctccgacg gcagcggcac gctggtgggg cgttggctca atttttaccc ttcgcagcag
    67801 aagcagctcg cgccgggcgc acgcgtacgc ctgttcggcg aggcgcgtgg cggcttcttc
    67861 gggctcgaga tggtgcatcc gcgcctgcgc gcggtggcgc ccggcgatgc gctgcccgat
    67921 gcgctgaccc cggtttatcc gaccaccgcc ggcgtcggcc agctcacgct gcgcaagctg
    67981 gtcgcgcagg ccctgcacag cgagtcgctc gacgagttgc tgcccgccga ctggctgcgc
    68041 cgcctcggcc tgcccggctt cgccgaggcc ttgcgcgcgc tgcaccaccc cgcgccggat
    68101 gccgacccct tcgcgctcga gcagcgcgag caccccgcct ggcagcgcat gaagttcgag
    68161 gagctgctgg tgcagcagct ctcgctgcgc cgcgcctggc tggcccgccg tgcccaggcc
    68221 gcggtggcgc tgccggcgcg cgggttgctc accgcggccc tgctcgattc gctgcccttc
    68281 cgccccaccg gcgcgcaggc gcgggtgggc gcggagatcg ccgccgacct cgccgcgccg
    68341 catccgatgc agcgcctgct gcagggcgat gtcggctcgg gaaagaccct ggtcgccgcg
    68401 ctggcgatgc tgcaggcggc tgagaacggc tggcaggcgg cgatgatggc gcccaccgag
    68461 atcctcgccg agcagcactg gaagaagctc tcggcctggc tggaaccgct cggcatcggc
    68521 gtggcctggc tgtcgggcag ccgcaaaaaa cgcgcgcgcg cggccgagct cgcccgcctg
    68581 gcgagcggcg aggtgctgct cgcggtcggc acccatgcgc tcatcgagga cccggtgacg
    68641 ctgccgcggc tggcgctggc ggtggtcgac gagcagcacc gcttcggcgt tcgccagcgc
    68701 ctggcgttgc gcgagaaggg cgagggcgga cggcggccgc acatgctgat gatgtcggcg
    68761 acgccgatcc cgcgcacgct ggcgatgacg cactacgccg atctcgacgt gtcggtgctc
    68821 gacgagctgc cgcccgggcg cacgccgatc cgcaccaggc tggtctccga cgtgcgtcgc
    68881 gacgaggtgg tcgcgcgcgt gcgcgccgcc tgcctggagg gccgccaggc ctactgggtg
    68941 tgcccgctga tcgaggagtc ggaggcgctg cagctgcaga ccgcgcagga caccttcgcg
    69001 acgctggtcg aggcgctgcc cgagctgcgc gtgggcctgg tgcatggccg cctgaagaac
    69061 gaggagaagt ccgccaccat ggccgccttc tccgccggcg agttcgacct gctggtggcg
    69121 accacggtga tcgaggtcgg cgtggacgtg cccaacgcca gcctgatggt gatcgagcac
    69181 gccgagcgct tcggcctcgc ccagctgcac cagctgcgcg gccgggtggg gcgcggcacg
    69241 gcggagtcgg tgtgcatcct gatctacgcc cagccgctgt cgcagaccgg tcgcgagcgc
    69301 ctcaaggtga tctacgagaa caccgacggc ttcgcgatcg cgcgcgagga cctgcgcatc
    69361 cgcggcccgg gcgagttcgt cggcgcgcgc cagagcggcg tgccgctgtt gcgctacgcc
    69421 gacctcgaga tcgacgccgc gctgatcgag cctgcgcgcg agctcgccga gcacctgctc
    69481 gcccacgacc ccgcctccgc caacgcgctg atgcggcgct ggctgggcgg gcgcgaagcc
    69541 ttgctgcgcg catgacgacc gtagccgccc ctgtaggagc gccggcaggc gcgaacatgg
    69601 cgcttcgggc gtcgacgtgg ccggcacgat cggcggcggc cttcgcgcct gccggcgctc
    69661 ctgcaacccc cccccacccg tgacgcctcc tgcatgggaa tcgcctctac tgcctgaatc
    69721 gatgcgtccc ctgaccgcct ttcccctcca caccggcccg cgccacgaga cctggcttgc
    69781 ccatccgccg cgagccggca tccttaagcc agggcagcag cccggccggc agcacggcgc
    69841 gcatccgtgc gcgctgcgcc ggcttcgagg tccgcgtgct gtgccagcgc ctcgcccgcg
    69901 tgcggcgcga cgaggcgctg ctgctcggcc tgcgcgcggg cgagctcgcc tggctgcgcg
    69961 aggtgctgct ggtggccgac agccgcccgg tggtgttcgc gcgctccttg ctgccgcgcc
    70021 gcaacctgcg cggggcgtgg aatctcttcc atggcatcgg cgcccgcccg ctcggcgcgg
    70081 cgctgttctc cgacccggcg atcgcgcgcc tgccgctcgc gtgcaggcgt ctggacgggc
    70141 gcgatgcgcg gtatcatcgc gcagccgcgg cgctcgcccg ccagtcccct gcaccggcgc
    70201 tgccggccgc gctgtgggcg cggcgctcgg tcttcctgct gcggggccgc gcgctgatgg
    70261 tgagcgaggc cttcctcccc gcaatcctgg aactgcgcaa atgacccccg ccatgagcct
    70321 gagcgacaag cttccccact acgcccgcct gatgcggatc gacaagccga tcggcaccct
    70381 gctgctgctg tggcccacgc tgtgggcgct gtggatcgcg gcggagggtt ggccgccgct
    70441 gtacatcctg gccatcttca tcgccggcac cttcctgatg cgctcggccg gctgcgtcat
    70501 caacgactac gccgatcgcg acttcgacgg ccacgtcgag cgcacccgca accgcccgct
    70561 cgcgaccggc gtggtgagcc ccggcgaggc gctcgcgctc gccgccgtgc tgtcggcggc
    70621 cgccttcgtc ctcgtgctgc cgctcaatac cctcaccatc ctgctctcgg tacccgcgct
    70681 gctgctcgcc ggcagctatc ccttcaccaa gcgcttcttc gccatccccc aggcctacct
    70741 cggcatcgcc ttcggcttcg gcatcccgat ggccttcgcc gcggtcaccg gcacggtgcc
    70801 ggcgaccggc tggctgatgc tgctcgccaa catcttctgg gcggtggcct acgacaccga
    70861 gtacgccatg gtcgaccgcc cggacgacct caagatcggc atcaagacct cggcgatcac
    70921 cttcggtcgc cacgacgtgc tcgcggtcat gctgtgctat gccgccgcct tcgccctgct
    70981 ggccgtcgtc ggtgtgctcg ccgggctggg cttcgcctgg tatctcggcc tcgtcgtcgc
    71041 ctgcgcgatc gccggctacc actacaccct gatccgcgcg cgcgagcgtg ccgactgctt
    71101 caaggccttc cgccacaaca actgggtcgg cggcgcgatc ttcgccggcc tcttcatcga
    71161 cctcctgctg cgcgcctgag ccctgccggc gcctcccccg gaccgatccc catgcacttc
    71221 atgaccgccc tccgcgccgc ctggcagcag cgcgacagcc tgctctgcgt cggcctcgac
    71281 cccgacccgg cgaaattccc cgcccacctg cagggccggc ccgacgccat cctcgcgttc
    71341 tgcacgcaga tcgtcgacgc caccgccgac ctggtgtgct gcttcaagcc ccagatcgcc
    71401 tacttcgccg cccaccgcgc cgaggaccag ctcgaggcct tgatcgagca catccacgcc
    71461 gcccaccccg ataccccggt catcctcgac gccaagcgcg gcgacatcgg cagcaccgcc
    71521 gagcagtacg ccatcgaggc cttcgagcgc ttcaaggccg acgcgatcac cgtcaatccc
    71581 tacatgggtc gcgactcggt cgatccctac ctggcctggc ccgacaaggg cgtgatcctg
    71641 ctctgccgca cctccaaccc gggcggctcc gacctgcagt tcctcgaggt cgatacgccc
    71701 catggccgca tgaagctcta cgagcacgtc gcccgcaccg tcgccgacga ctggaacgcc
    71761 agcggcaact gcgccctggt ggtcggcgcc accttcccgg ccgagatcgc gcgcgtgcgt
    71821 gaactcgtcg gcgatatgcc gctgctcgtg ccgggcatcg gcgcgcaagg cggcgacatc
    71881 gccgcgaccc tggcggcggg acgcacggcc aacggcagcg gcttgatgat caactcctcg
    71941 cgcgcggtgc tgtatgcggg gaagggcgag gacttcgcac aggctgcgcg cagggtggcg
    72001 caggagacgc gggatgcggt caatgtgcat cgcgtctcga agtgacgctt attccacttg
    72061 caatgccaat tgaagtcggg ttgactgtcg ggcgctcgcg cccagctgtc cgggtgccga
    72121 ttcatcatct tcgccacgag ggagtcagat tgtgttcagg ttgaaaaacg aagcgttgct
    72181 caagggtctg ctgctcgcag gagcgaccgt ggtgctcgtg gggtgcggtg gcggaggtgg
    72241 cggtggtggg ggggttcccg gtgggccaac gcccgaaggg gggggctccg ggggcggagt
    72301 cgtcaccgag ccgaccgtga ccttgagcct gaccgatctg ggcgcaggga ccacgagcaa
    72361 tagcttgtct ttcgggcaga acctcaaggc gacggcgctt gtgctcgaca agaccggcaa
    72421 gcccgttccg aatgcgatcg tcagttttgg ggcgagcccc gactcgctgg ttgcgttgat
    72481 cccggatgtt ggaaccgcgc tcactggcgc ggatggaaaa gcttcgatcc agttggccca
    72541 acagagtctc acttccgcgg gcgcaggaac cctgacggcg cgatccgagg tcgacggtgt
    72601 ggagacggcc gactccgaga atttcagcgt gagccctgcg agtgtcagcc tcgagcagat
    72661 gcaggtcggc cggagtccgc tttcggccta tggaaccacg agtgtctcgg tcgatgtgaa
    72721 aggcgtgccg aacaccgtac cggttactgt cgcatttacg tccaattgcg caacccttgg
    72781 aaaagcgaac ctgacgcaga gcgtgatctc gttgaacggc aagtcgattg ccaactacga
    72841 ggacaagggt tgtgcccgga cggatacgat caccgcaacg gtcgccggaa cttcggtttc
    72901 gacttcgacc agcctgcagg tggaggcccc cggtgtttcg agcatccggt tcatgtcggc
    72961 gagtcctgaa acgatcgtgt tgaagggaac gggctcagcc gattttccgg aggtttcgca
    73021 ggtcagtttc aaggttgtcg acagcaacgg tgcgccgatc cagaacgcgc tcgtgacctt
    73081 ttcgttgagt acggcgaccg gcggcatcct gcttgaatcc acggcggttt ccgggccctc
    73141 ggacaccgtg accaagagta ccggagctga tgggctggtt caggttacgg ttcaatcggg
    73201 cacgattccg actccggttt gggtgatagc aagcacgacg gattcgggtg gcaaagccat
    73261 cacgactcag tctgtgaagc tgagcatcag taccgggcgc cctgcgcagg accgcatgtc
    73321 tcttgccgtt gagagccaca acatcgaggg ccttgattac gatggtcagg ccgttaaggt
    73381 cacggctcga ctctcggatc ggcttggaaa tcctgtgccg gacggtaccg cagtcaactt
    73441 tatcgccagc ggtgcacaga tcggcgcgac ttgccagacg gaggtgggcg catgctctgt
    73501 cgatttcgtc agcggtaacc cgcggctgaa tggcaggatt gcgatcctgg cctatgccct
    73561 cggagaggaa agctttctcg atctcaacag cgacaacctt tacgcgctcg ctgtggaggg
    73621 gcctaacttc actgatttgg gcaatgcgtt cctcgatcgg gacgagaatg ggcagtttga
    73681 tgccggggag cagtcggttc cttatgggtc aggcagttcc ggctgcgtga atcgtttgtc
    73741 gacatctcct ggtgcgccga gtgttagcgg cacctgcgac ggagtgtggg gaccagcgca
    73801 cgtgaggcag gagaatgtga tcgtgctttc cggctccgat gcattcctga gccggactcg
    73861 tttcagcatg gcgggcgagt gctcttacac cgttgatgat ttcagattgt tcgaccgcaa
    73921 caataacccg atgccagaag gatcgaaaat cgaagcgatc gtcgaaggaa ccgagttcac
    73981 atcggcaacg gtaactccga atatcgtgcg tgataccgca gctccgggcg gaacctacca
    74041 ttcgctcacg ctgaaacgta aggaaacctc cggctgcgac accgctccgg atcgcacctt
    74101 gccgttggag atcaccactc cgagggggaa tgtgacgccg attactctga cgatcacgaa
    74161 atgatctgac cgctggcact aaccgggcgg ggcgtttgca ggagggggcc ttcacgcatt
    74221 ggttgtgcga acgcctccga aggccggcga aagccggcct tcgcgttttc gggtagggac
    74281 gatcagcccg ctataatccc gcccatgaac tactccgacc tccgcgactt cctcacccag
    74341 ctcgaagccc gtggcgagct ccgccgcatc aagaccccag tcgacaccta cctcgagatg
    74401 accgagatcg ccgaccgcgt gctgcgcgcc ggcgggccgg ccttgctgtt cgagagacca
    74461 gtgaccaagg gcgtgccgca ggcgatcccg gtgctcgcca acctcttcgg cacgccgcag
    74521 cgggtggcga tggggatggg ggaggacgtc accgacggca actggagcgc gccgctgcgg
    74581 gaggtcggca agctgcttgc ctacctcaag gagcccgagc cgcccaaggg cttgaaggac
    74641 gcctgggaca agctgccggt gctgaagcag gtgctcaaca tggcgcccaa ggaggtccgc
    74701 tccgcaccct gccagcaggt ggtgtggtcg ggcgacgagg tcgatctggc aaagctgccg
    74761 atccagcact gctggccggg cgacgccgcg ccgctgatca cctggggcct ggtggtgacg
    74821 cgcgggccgc acaagaagcg ccagaacctg ggcatctacc gccagcaggt gatcgggcgc
    74881 aaccgcgtga tcatgcgctg gctggcgcat cgcggcggcg cgatcgactt cctcgagcac
    74941 cagcgcgcgc atccgggcga gcccttcccg gtttcggtgg tgctgggctg cgacccggcg
    75001 accatcctcg gggcggtgac gccggtgccg gattcgctct cggaatacca gttcgccggc
    75061 ctgctgcgcg gggccaagac cgagctggtg aagtgcctcg gcaatgatct gcaggtaccg
    75121 gcttcggccg agatcgtgct ggagggcgtc atccttccga atgagacagc catggaaggc
    75181 ccctacggcg accacaccgg ctattacaac gagcaggccg aatttccggt gttcaccgtc
    75241 gagcgcatca ccatgcgccg cgacccgatc taccacagca cctacaccgg caagccgccc
    75301 gacgagccgg ccatgctggg ggtggcgctc aacgaggtct tcgtgccgct gctgcagaag
    75361 cagttcaccg agatcgtcga cttctacctg ccgccggagg gctgttcgta tcgcctggcg
    75421 gtggtcagca tccgcaagca gtaccccggc cacgccaagc gggtgatgtt cggcatctgg
    75481 agcttcctgc gccagttcat gtacaccaag ttcatcatcg tggtggacga ggacgtgaac
    75541 atccgcgact ggaaggaggt gatctgggcg ctcaccacgc gcatggacgc cacccgcgac
    75601 accacgctgg tcgacaacac gccgatcgac tacctcgact tcgccagccc ggtcgccggc
    75661 ctgggcagca agatggggct ggacgcgacc aacaagtggc cgggcgagac cagccgagag
    75721 tggggcacgc cgatcgtcat ggatgcggcg gtgaaggcga aggtcgatgc gatgtggggc
    75781 gagctggggc tgtagggcgg gcgcgcgtta cgttttgttg ttgcactgca gccgaacgcc
    75841 cggcatggtc ccgggtcgaa gcctttgtca tgcgctgcgg atgttcccgg cgcgggctcc
    75901 cgcttgagga aaatcgatga gcaatcccta tcccgcgccg atcggggccg gccagccctc
    75961 cgagaacatg gtcaccgtca cccacctggt gtatgcgctg cacgccttcg cggtgttctc
    76021 ggcggtggtg ggctcggcga cgatcatctt cagcttcgtc gccagcctgc cctccatcgc
    76081 cgcggtgatc ctgaactact ggaaccagaa tgcggtgcgc ggcacctggc tggagagcca
    76141 cttccgctgg cagatccgca ccttctggtt cgcggtgctg tggatcgcgg tatcggcgct
    76201 gatggtggtg accatcattg gcgtgccctt cgcgctcgcg ctgctgctca ttgccgggct
    76261 gtggatcctg taccgcattg tgcgcgggtg gtggaacctg atgcagcggc agacgatgcc
    76321 gatggcgtga ggcttgaggc ttgaggcttc gctcgcgtgt tgcggagatg cttcccgggc
    76381 ggccgtattc gcgcctgccg gcgctcctac aagggggccg gctgcgcggt tttctgtagg
    76441 agcgccggtg gttcgcggcg cccgcgtcga tctcttcgcg gccctgttcg cgcctgccgg
    76501 cgctcctaca tcaaccggcg cgcgtccgac ccgctgtagg agcgccggca ggcgcgaaag
    76561 cggggcttcg ttacccccgg ccttcattct ccgccgctcc acagccactc cagcaaggcg
    76621 tcctgggccg cggcgctggc ggcggcgtcg gggtggttca ccatcatcac caccacatgg
    76681 cgctggcctt tgcggtcgag caggtagccc gccatcgcgc gtacgccgtt gagcgtgccg
    76741 gtcttgatgt gggcctggcc gcgtgccggg ctgtcgccaa ggcggcggcg ggcggtgccg
    76801 tccagccccg ccaccggcag ggcggcgatg aactccggca tccacggccg ctgccagacg
    76861 gccagcaaca gcgcacccag gctgtcggcg cggatgcgct cgttgcgcga cagccccgag
    76921 ccgttctcga tcaccagccc gtcggtgtcg atgccggcgg cggccagtgt cgcagcggcc
    76981 gcgcgggcgc ccgccgccac catgtcctcg gtggcgtcct cgcgcaggct cacgcggccc
    77041 agcgtggcca gcagctggcg cgcaatcacg ttgctcgacc atttgttcat gtcgcgcacc
    77101 acgtcggcga gcgggtcgga gtcgtccccg aacagctcct ccgcactcgc cgccagccgg
    77161 ccttcgcgta cggtcccgcc cagtcggccg cccacttcgc tccacagcgc ggcgacgagc
    77221 gcgctgccga actcggccgg cggcagcggc gcggcgctcc aggtgcgcgg gccgcaggcc
    77281 gcgggcaggc tgccgctcag caccaggcga cgcccgggct cgagtgtggc ctgcaggtcg
    77341 cggtaccagg tgccgcaggg cgcatccgag gtgaggatgc ggttgtcgat gacgaggccg
    77401 gcgagtggcg gctcggcggc cagggtgacc ggcgcgttgg ccaccttccc cgggtgcagg
    77461 ccgagcagca gggtgttgta gtgcagcagc agaccgtgcg gcccgctgtt gtacgggcgc
    77521 aggccgcggc cgtcgaaggc gtcggggtcg tgtggaggca ggcgcagtgc cgaggcgtct
    77581 agcacgatgt cgccggcgat gcgctcgacg ccgagcgcgc gcagccggcg cagcatcttc
    77641 cacaggcgat cgtagccgag cacgggatct gccccgccga cgaggtagag gtttccttcc
    77701 agcacgcccg cgcggagcgg gccgtcgccg gcgatgcggg tcgtccaggt gtgggcgggg
    77761 cccaggcgct cgagtgcggc gaaggcggtg acgagcttca tcaccgaggc cgggttcatt
    77821 gccgcgccgg cgttgatcgc gagagtgggg gcgggacggt ccaccggacg cgcccagacc
    77881 gcgatcgcct ccacgggaat ttgcgcgctg tccagggcga ggcgcactcc gggcggaagc
    77941 gcattgccgt cggcatggcc gggcccgacc agcagcaggc tggtgacgaa gatcacgcac
    78001 agggaaagat tcttcatgag catgtcaggg atcctgatcg agcctggacc ggcgaggcgg
    78061 taaaatgctt gcctggcctg cgtgcttgcg cggcggattt tatacggagc ggcaaatccc
    78121 gtttgcatga gtggtcgtgc ggcgggcttg cacgggaaag atgagcggat tcggacatta
    78181 cgcgcgcact gcggacgagc tggagcgcga gatcctcaag cgcgggatcg cgatcgggat
    78241 cgactgggac gatccgtcgc gcatgcgcga ccttgcccgt cgcgcgttga gctgcacgcc
    78301 tgcctgcatg atgaagctgc tgcgcagccc cgtgcgccag gacaagctga ccggtgagct
    78361 gttcgcgctc tccgagctga tgctgcagaa catgcgcgag agtgccgaga tcggcttcga
    78421 gacccatggc ggtccggcgt ggaaggcctt cgggcgcgcg ctcaacgagg agttcgacgc
    78481 tggcgtgcga ccgcccgagg ccggcgcctg aggccggctc attcgccgcg agcgcaagcg
    78541 gatcgggcac gggtgctgcg cccggcgagc cggatcgccc cgcgcccgtt gtcttacgcc
    78601 ggtacgcgct cgcgcgcgaa cagctcttcc accgtctcgc gttcgcgcac cacatgcgcg
    78661 ctggcgccat cgaccaggat ctctgcggcg cgcggtcggg tgttgtagtt cgaggccatc
    78721 gtcatgccgt aggcgccagc cgacaggatc gcgagcaggt cgccctcggt cactgccagg
    78781 tcgcgctcgc gcgcgaggaa gtcgccgctc tcgcagatcg gcccgacgac gtcgtaggtg
    78841 gtgggggcga gcgtgcgcgg ggcgacctcg accacatcgt gccaggcgtc gtagagcgcc
    78901 ggacgggcga ggtcgttcat ggcggcatcg acgatcgcga agttcttggt ctcgcccggc
    78961 ttgaggtact cgatgcgggt cagcagcagg ccggcgttac cgaccaggga gcggccgggc
    79021 tcgaagcaga gctcctcctc gcggccggcg aagacctcca gcagcggcgc gaggtagtcc
    79081 gcgaccggcg gcggggtctc gtcgcgatag cggatgccca gcccgccgcc caggtcgatg
    79141 tgttccagcg cgatgccgtc ggcggcgagg cgctcgacca ggtcgcgcac cttgtacgcg
    79201 gcttcggcga tcggcgcgcg gtcgagcagc tgcgagccga tgtggcaggc gacgccggtg
    79261 atgcgcaggt tgcgcagcgc cgcggcgcgg cggtaaatcg caggggcctc ggcgaaggcg
    79321 acaccgaact tgttgccctt gaggccggtg gagatgtagg ggtgggtctt ggggtcgacg
    79381 tccggattca cccgcagcga caccggcgca ctcacgccga gttcgcccgc aaccgcgtcg
    79441 aggtgctcga gctccgccgc agactcgacg ttgaagcagc ggatgcccgc ctgcagcgcc
    79501 tggcgcatct cggcgcgcgt cttgccgacg cccgagaaca cgaccttgtc ggcacgcccg
    79561 ccggcggcca gcacgcgcgc gagctcgccg cccgagacga tgtcgaagcc cgcgcccagg
    79621 cgcgcgaaca ccgacaggat gccgaggttg gagttggcct tgaccgcgta gcacaccagc
    79681 gccgggcgtc cggcgagcgc atccttccag gccgtgaagg cggcttcgag cgcggcgcgc
    79741 gagtatacat aggtgggcgt gccgaagcgc gcggcgatct cggcgagcgg caagtcctcg
    79801 agccagagcg cgccgtcgcg cgcggacagg gtgggggcgg gccagcgggc ggcgggggcg
    79861 ttcattcgag gggcgattcc ttgatcagat ccttcggcac gacgggtttg ctatgatcgg
    79921 cgcccgccgg gggcgacgtg gtggtgccgg gtgccggcag gtagagcggg cccttgatgc
    79981 cgcaggcgga cagcagcgcg ctggcaaggg cgatcgcggg gagtcgggct cgcatcgtgg
    80041 ctcgcttcat ggctcgcnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    80101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnntgg
    80161 ctcgcttcat ggctcgcatc gccgttcttc gcaaaaaacc ggaatgctaa cagaaggaat
    80221 cagcatggaa gagtctgcgt tcaatgcgct cgccgaggcc gagctggcgc gcatcgagac
    80281 cgccctggag gactgtggcg cggagctcga cgtcgagccc aagccgggcg gcatcctcga
    80341 gctcgagttc gacaacggca gcaagatgat catcaaccgc catacggcgg cgcgcgagat
    80401 ctgggtggcg gcgaagtcgg gcggcttcca cttccgtccg caggacggag tctgggtcaa
    80461 cacccgcgat ggacgcgagc tgtgggcgat gctcgccgcg ctggtgggcg agcagtcggg
    80521 cgaggcggtg aggctggtgc ggcgcgattg agggtggcgg gtcttgccgt ccgctttcgc
    80581 gcctgccggc gctcctacaa aaccaccgcg cgtccagcct cctgtaggag ctgcggcagc
    80641 tgcgcacacg gcgacttcac aatcgacgcg tgcgcggaat cccatcgccg cctccgcgcc
    80701 tgccggcgct cctacaaggc gctggcgctt ttgtaggagc ggcggaagcc gcgaagcttt
    80761 ctttacggcc ggatcggcgt ggggcggcgc tcctcgaccg gggcgggggc ttgcgcgcgc
    80821 gcggggccgg gcggcggcag gatgagcggg gcggggccgg gcgggatcgc ctcggcctcg
    80881 gcctccatcg ccggcgcgct gtcgccggcg aacatctcgc gcagccagtc cggaaccggc
    80941 ggcggcgtgg gcggggcgta ctcggcgtac tgccagtcct gctgggtgcc gaggccgttc
    81001 tgaacctggc gcaggccgtc gggacgcggc agctccacct gcggcgtgcc ttcgagcgcg
    81061 gacgccatgt agttgatcca gatcggtagc gccgcggcgc cgccggtctc gcccttgccg
    81121 aggttgcgcg gctggctgtg gccgacccag ctcaccgcga cgaggtcggg gtggtagccg
    81181 cagaaccagg cgtcgacgta atcgttggtg gtgcccgtct tgccggcgag atcctcgcgc
    81241 ttgaggctgc gcgcgcgcgt ggcggtgccg cgctgcacca cgtcgcgcat catcgaatcc
    81301 atcagccagg cgttgcgcgc gtcgatcacc cgcggtgcgc tctggccggc gaccggcggg
    81361 tcggtgcgcg cgatcaggcg accgctgccg tcgtacatct ccttgatgac gaagggctcg
    81421 acgcggtagc caccgttggc gaacaccgca tagccggccg ccatctgcca cggcgtggcg
    81481 gcgcccgcgc cgagcgccat ggtgaggtag ggcgggttct gcgcggggtc gaagccgaag
    81541 cgggcgagat agtcgcgcgc gtactcgggg gtgatcttct ccagcaggcg gatcgacacc
    81601 atgttcttcg agcgcgccag gccgtcgcgc agcgtcatcg ggccggagta gcgcccgtcg
    81661 tagttcttgg gctcccaggc cttgctgccg gtgacgccgg ccgggtagta gagcgggttg
    81721 tcctcgagca cgctgcccgg gccgaactcg cggtcgaggg cggcggagaa aatgaagggc
    81781 ttgaagcttg acccgggctg gcgtaccgcc tgggtcacgt ggttgaactt gttgcggttg
    81841 aagtcgaagc cgccgatcag cgcgcgcacc gcaccgctgc gcgagtcgat cgccagcagc
    81901 gccgcctgca cctcgggcag ctgcgtcagc tcccaggcgt ccttgcccgt gttgcgtacg
    81961 cgcacgatcg caccgcggcg cacgcgccgc gcctgcggcg ccttctccga cagcatcggt
    82021 gcgacgaagg acaggccctt gccggtgatg cggatctcct ggccgcgccg atagacgagc
    82081 acctccttcg ggccggcctt gagcaccagc gcggtaagga ggtcgtcgtg gtcgctgaat
    82141 tcgccgagcg cctcgtcgag tcgttcgccc gcgacctggc cggagggcag gtcgacgaag
    82201 gcctccgggc cgcggtagcc gtggcggcgg tcgtagtcga gcacgccgcg gcgcagcgcc
    82261 gcataggccg cttcctgatc cttgcgcgtc accgtggtga cgatgcgcag gccgagctcg
    82321 taggcctgct cgccgaactg ctccaccgcg atctggcgtg ccatctcggc gacgtagtcg
    82381 ccgggcacga cgatgtcggg aacgcggcgg gcggcggcga tgtcgcgctg gctctgcttc
    82441 ggggtggcga aggcgagcgc ctcctcgtac tgctgcgggg cgatgaagcc ggcctcgagc
    82501 atgcggcgca gcacgtactg ctggcgcacc gcggcgcgcg ccgggttcac gatcgggttg
    82561 aaggcggagg gtgccttggg caggccggcg agcatcgccg cctcgggcag ggtgagctcg
    82621 tcgagcgtct tgccgtagta ggcacgtgct gcggcggcga agccgtaggc gcgctggccg
    82681 aggaagatct ggttgatgta gagctcgagg atctggtcct tggacaggtt ctgctcgatc
    82741 ttgagggcga gcaggatctc gtagagcttg cggttgtagg tcttctcgcg cgagaggaag
    82801 aagttgcgcg cgacctgcat ggtgatcgtc gaggcgccct ggccgcggcc gccggacgaa
    82861 aggttcgcga gcgccgcgcg cgccaggccg aacgggtcga tgccgcggtg ctcgtagaag
    82921 cgctcgtcct cggcggcgag gatggcgtgc ttgaggtggg agggaacctc ggcgatgcga
    82981 accacgtcac ggcgctcctc gccgaactcg ccgatgaggt ggccatcggc cgtatatact
    83041 cggagcggaa cgcgcggacg gtagtcggtg agcgtgtcga gcgcaggcag cttgggccag
    83101 gcgaagaagg ccatcgccgc gagcgtggcg atgccgagaa tggccagcgc gaacagcgct
    83161 gcgatcggat acaggaccca gcgcatgggc aatccaggat ggtttcgagc ggagcggcat
    83221 tatacgggat gcgcccgccc ggctctcgtg cccgaccgta agtgcatgtc aaccgtgacg
    83281 gggtttgctt tacaccccaa tggcttgttg ctagcatgct agagccctgt tgaaaaacag
    83341 cgcgtaacat aaagaaattc aagggttttc tttgtgatcg acctcccctt tttaagcccc
    83401 tcggcgcgcc agctcgtcgg gctcgacatc tcgtcttcat ccgtgaagct cgtcgagcta
    83461 tcgggcgggg aaaaggacgc ttacaaagtg gagcgctatg cggtcgagac cttgccgcgc
    83521 gatgcggtgg tcgacggcaa catcgccaac ctcgacgcgg tgagcgaatc ggtgcggcgc
    83581 gcgttgcggc gcttcggcac gggggtgcgc aacgtggcgc tcgcgctgcc gtcctcgtcg
    83641 gtcatcacca agaagatcat cctccccgac ggtctgcgcg agaccgagat ggagttcgcg
    83701 gtcgaggccg aagccaacca gtacattccc tttgcgctcg aggaggtcaa cctcgacttc
    83761 cagcgcatcg gccccgcgcc cggcagcccg ggtgacgtcg aggtgctgat tgccgcctcg
    83821 cgcaaggaca aggtcgagga ccgcgtcgcg gtggccgagg cggccgggct caaggcggtg
    83881 atcgtcgatg tcgagtcgct cgccaccgag tccgcgctcg agctggtctg ccgccagctg
    83941 ccgcggggtg gcgccgatca ggtcatcgcg ctggtcgaca tcggcgcctc ggtgatgaac
    84001 gtgaccatgt tccgcaacgg tcattccatc tactcgcgcg agcaggcctt cggcggcagt
    84061 cagctcaccc aggacatcgc gcgccagtac ggcatgagct tcgaagaagc cgagtctgcc
    84121 aagcgtgcgg gctcgctgcc cgacagctat ccgcgcgacc tgatgcgccc cttcatggac
    84181 agcctcgcgc tcgaggtctc gcgtgcgctg cagttcttct tcacctcgac gccgttcaac
    84241 caggtggacc acgtcgtgct agccggtggc tgttccgtgt tgccggggct tggcgacgtg
    84301 gtcgcggcgc gcacccaggt cgacaccctc atcgccaacc ccttcgccgg catgaccctg
    84361 agcggcaagg tgaggccgaa ggcgctgctc gccgatgcgc ccgcgctgat ggtcgcctgc
    84421 ggcctggcgc tgcggaggtt cgacgcatga tccgcatcaa cctgcttccg catcggatcg
    84481 ccaagcgccg tcagcgccgc cagcagttct acgcgctggc cgcgggcatg gtgctgttgg
    84541 gtgccctgat cggcttcggc gtacacatga tctatgccgg gcatatcgaa cggcaggagg
    84601 cgcgcaacgc tttcctcaag caagagatcg cccgtgtcga ccgcgacatc gccgagattc
    84661 gccgcctgcg cgaacagatc gacgcgatgc tggcgcgcaa gcaggtcatc gagtcgctgc
    84721 aggggacgcg cgcggagacc gttcatctgt tcaacgagct cgcccagcgc ctgcccgacg
    84781 gggtgtacct caagtcgacc aagcagacgg ggcgccaggt cagggtggtc gggctggcgc
    84841 agtccaatgc gcgcgtgtcg catttcatgc gcaacgtcga agcctcggcc ttcctcgagc
    84901 agccgaggct gatcgaggcc aaggcggtca cgcaggacaa tcgccgcttg agcgagttca
    84961 ccctcgatat cgccatccgg ccgccggtcg aggctgagcc cgaggcggcc gcaagcgcgc
    85021 cgaaggcggt cgcgaagggg gcgcagaaat gagattggat ctcgccgcat tgcgcgaagg
    85081 catcgatttc cgccgcctcg cggaagactt caaggggctc gatccgcagg atccgggcat
    85141 gtggccgacc gctccgcgca tcgtggtcgc ggtcctgttg ctggtgctca cggtagccgg
    85201 attctggtgg ttcgactggc aggatcaggt caagaccctg gaggcgcgcg aggctgaaga
    85261 ggtgcagttg cgcgagagct gggtcgtcaa gaagcgccag gcggtgaatc tcgaggagca
    85321 ccgccgccag cttgccgaga tcgaccggca attcggtgcg ctgctcaagc aactgcccaa
    85381 tcgtgccgaa atggactccc tgctctccga catcaaccag gccggcctcg gccgcgggct
    85441 tcagttcgag ctgttcaagc cgggcaccga cgtcatcaag gagttctacg ccgagatgcc
    85501 gatcgacgtg cgcgtgaccg gcgtctatca cgacctcggc gagttcgtcg ccgacctcgc
    85561 cagcatgcca cgcatggtga ccctcaacga tgtcggcatc gatgcggaca aggacgggcg
    85621 gctcaagctg caggccaagg cagtgacata tcgctacctc gacgaggaag agctcgccca
    85681 gcagcgcaag gcggcgcagg cggcccaggc cgcgaagcag gggaagaaat gatgaacagg
    85741 gccgcgatga tcggcgcctg tgtgctgctc gccggatgca cggggggcag ccaggacgac
    85801 ctgaagacct ggatggacga gcaggcaaag accatgcggg gggcggtccg accgcttccc
    85861 gagcttcgcc aggtgccggt ggtggcctat gccggcacgc agggcgacga tccctttcgt
    85921 atcgggcgca tggagcccga gcggcgcgcc tcggccagcg cccttcgtcc cgacctggac
    85981 cgccggcgcg agccgctcga ggccttcccg ctcgaatcac tgcagatggt gggcgtgctg
    86041 atgcagggaa acaacaccca cgcgttgatc aaggcgggga cggtgctgca tcaggtgaag
    86101 gtcgggaact acatgggaca gaatttcggc gtgatcacgc agatcaccga gaacgagatc
    86161 aagctgcgcg aactggtcga ggatgtctat ggcgactggg tggaaaaagt cagcgacctg
    86221 aaactgcagg agcgcggaga ggccggaaaa tgagacaccg catcggagtg ctgctgatcg
    86281 cagccgcttt cgcaggcctg gcgcctgcgc ccgccgtgct ggcccaggac gcatcgcaga
    86341 cgcagagctt cagcaatcag atcgaggggc tggaggtcgc cgagcagggc ggcgccatct
    86401 atgtgcgcct gaccttgcgc gaaccgctcg cgagcccgcc gccgagcttc agcgtggcca
    86461 acccggcgcg catcgccttc gatttcccgg gtactgccaa cgccctcggg cgcaacgtcc
    86521 aggccatcga ccagggcgac ctgcgcagcg ccaacatcgt ccaggcgggc gatcgcaccc
    86581 gcctggtgct caacctcacc cgcatgagcc cctatgaggc gcgcgtgcag ggccgcgacc
    86641 tcatcatcgc gctgtcgccg gccgcagcgc gcgcggcgca gggttcggtg gtgagcgaag
    86701 ccgcggccaa cttcgccgag ccgcgcgccg cagcggccgc agcgggtggc ctggcggtgc
    86761 gcgacatcaa cttccgccgc ggtaccgccg gcgaggggcg cgtggtcgtc gacctgtcca
    86821 gtccggacac cggcatcgac attcgccagc agggcggcaa cctcgtcatc gacttcctgc
    86881 agaccgcgct gcccgaacat ttgcgccggc gctccgacgt caccgacttc gccaccccgg
    86941 tcacctcgat gaccgcccag caggtgggcg atcgcgtacg cctgaccgtg acgcccaacg
    87001 gcttgtggga gcacaacgcc taccagagcg acaaccgctt cgtgctcgag gtgcggcgcg
    87061 tcgccgagga tccgaccaag ctcggcggcg ggcgcagcga ctacaagggc gagaagctct
    87121 cgctcaactt ccagaacgtg gacgtgcgct cggtgctgca ggtcatcgcc gacttcaccg
    87181 acttcaacat catcacttcc gactcggtgc agggcaacct gaccctgcgc ctgaaggacg
    87241 tgccctggga tcaggcgctc gacatcatcc tgcaggccaa gggcctggac atgcgcaaga
    87301 acggcaacgt gatctggatc gccccgggtg acgaacttgc cgcgcgcgag aagctgcagc
    87361 tcgaggccaa ggcgcagatc agcgacctcg agcccttgca gaccgagagc ttccagatca
    87421 actaccacaa ggccaaggag atcttcgatt tcctcaagag caaggaccag accatgctct
    87481 ccaagcgtgg cagcgtggtg gtggacgagc gcagcaacaa ggtcttcgtg accgacgtcg
    87541 ccacccgcct gcaggccttg cgccggctgg tgcaggagat cgacgtggcg ccgcgccagg
    87601 tactgatcga ggcgcgcatc gtcgaggcga gcaagacctt tgcgcgcgac ctcggcgtgc
    87661 gcctgggtgt gggcggggcc ttcggccgca tcgtcggcta caccgaggat ggcgcgccgg
    87721 tgcgtcgcag cacgctcggc ggcggcctcg gcgccacgcg gacgatggcg ggtcaggtgg
    87781 cgggcgtggt cgacgccaac cccgcgggct tgaacctcaa cctgccggcg gatgtgtcca
    87841 atcccggcct gctgtcgatg gtgctgtgga acaacaacgc cacccgcttc ctcaacctcg
    87901 agctgagcgc gctcgaggtc gatggccgtg ggcgggtgat ctccagtccg cgagtgctca
    87961 ccgccaacca ggtcgaagcc tcgatcgagc agggcaccga gatcccctac caggaggcgt
    88021 cgagctccgg cgcgaccagc gtgtcgttca agaaggccgt gctgtcgctc aaggtcaagc
    88081 cgcagatcac ccccgacggt cgcctgcagc tgtcgatcga ggtcaacaag gatcgcccgc
    88141 tctacgagca gaccctgctc ggcgtgccgc cgatcgagac caagaacgtc aagagcgagg
    88201 tgctgatcga gaacggcggt accgtcgtga tcggcggcat ctacgaggaa gaggagtcga
    88261 ccggcgagga caaggtgccg ctgctgggag acgtgccggt gctcggccac ctcttcaagt
    88321 cgcagagccg ggtgtcgagc cgcaaggaac tcctcgtctt catcaccccg cgcatcgtct
    88381 ccgacgcgct cacgctgcgc tgagtccggc acatctgctg atacaatccc ggggcgggca
    88441 tccggcatgg atgcccgccc tttttcatct ggatttccgg cgagtcacgc gtgagctgtc
    88501 tgatactgat cggcatgatg ggcgccggca agaccacggt cggcaaggaa ctggcgcgca
    88561 ggcgcaagat gcgcttcgcc gattgcgacc aggcgatcgt ggcgcgcacc ggcgtcagca
    88621 tcccgaccat cttcgagctc gagggcgagg cgggctttcg ccgccgcgag acgcagatga
    88681 tcgatgagct cacccgcgag cccgacctcg tgctcgccac cggtggcggg gtcgtcacca
    88741 cgccgctcaa ccgcgagctg atgcgcgagc gcggcatcgt gatctacctc gacgtgccga
    88801 cgcaggtgct gttcgagcgc acccgccacg accgcaatcg cccgctgctg caggtcgaga
    88861 atccgcgcca gcgcatcgag gaactctacc gcgcgcgcga ccccctctat cgcgagaccg
    88921 cccacatcat cctcgagggc ggtcgcggca accccggcaa catggtgcgc cagatcgagg
    88981 aggcgctcgc ccgctacaag gccgacacat gcagaccctg aacgtggcgc tcggcgagcg
    89041 cgcctatccc atccacatcg gccgcggcct gctcgggcgt gccgacctga tcctgcccca
    89101 cctcaagacg aagcgtgtcg cgatcgtcac caacgcggtg gtcgggccgc tctacctcga
    89161 gcgcctgcgc gccggcctgg aggccgcggg cgtgcgcaac gccgcggtgg tgctgcccga
    89221 cggcgaggcg cacaaggact gggagacgct gaaccgcatc ttcgacatgc tgctcgccga
    89281 gcactgcgag cgctccacca ccctggtcgc gctcggcggc ggcgtggtgg gcgacatggg
    89341 cggctttgcg gcggcctgct accagcgcgg catgcccttc atccaggtgc cgacgacgct
    89401 gctgtcgcag gtcgactcct cggtgggcgg caagaccgcg atcaaccacc cgctcggcaa
    89461 gaacatgatc ggcgccttct accagcccag gctggtgctg gccgacatcg acaccctcga
    89521 caccctgccc gatcgcgagc tctccgccgg tctggccgag gtgatcaagt acggcctgat
    89581 ccgcgacccc gagttcctcg tctggctgga ggccaacctc gaccgcctgc tggcgcgcga
    89641 caccgaggcg ctggcgtggg cgatcgagcg ctcctgccgc aacaaggccg aggtggtggc
    89701 ggccgacgag accgagcagg gcgagcgcgc gctgctcaac ctcggccaca ccttcggtca
    89761 cgccatcgaa accggcctcg gctacggtga atggctgcac ggcgaagccg tcgccgccgg
    89821 cacgatgatg gccgccgagc tgtcgcgccg cctgggctgg atcgacgccg gcgcggtggc
    89881 gcgcatcgag gcgctgttcg agcgcgcccg cctgccggtg tgggggccgc gcatgggcgt
    89941 cgagcgctat gtcgagctga tgtcgcacga caagaaggtc gaggccggca agctgcgcct
    90001 ggtgttgctg cgcgagatcg gctgcgcggt gatgcacggc gaggcaccgg cctccgagat
    90061 cgccgcggcg atcgaggcgc gctgccgctg agttcgcggc aggcgcgctc gcgggcaggc
    90121 tcgccgccgc cggcgggtcg gtcatactcg cgcaagagcg tcctgccgtt ttcgtcctgc
    90181 cgcgccactc gaggaggtcg catgctgcaa ctcgccccct atgccgttac cgaggccgcc
    90241 tcgcgcggcc gcgtccatga cgaacctgcg ccggtcgcgc gcggccagtt ccagcgcgac
    90301 cgcgaccgca tcgtgcattc caccgccttc cggcgcctcg aatacaagac ccaggtgttc
    90361 gtgaaccacg agggcgatct cttccgcacc cggctcaccc atagcatcga ggtcgcccag
    90421 ctcacccgcg gcatcgcgcg cgagctcggc ctcaacgagg acctcgcgga ggccatcgca
    90481 ctcgcccacg acctcggtca cacccccttc ggccacgccg ggcaggaggc gctcaatgcc
    90541 tgcatgaagg actatggcgg cttcgagcac aacctgcagt cgctgcgcac ggtggacctg
    90601 ctcgaggacc gctatgccgg tttcgacggg ctcaacctga tgttcgagac gcgcgagggc
    90661 atcctcaagc actgctcgcg cgtcaatgcc gagcgcctcg gcgagctcgg ccagcgcttc
    90721 ctcgatggca cccagccctc gctcgaggcc cagctcgcca acctcgccga cgagatcgcc
    90781 tacaacaacc acgacgtcga tgacggcctg cgctccgggc tgatcacgct cgagcagctc
    90841 gacgaggtgc cgatcttcgc ggtgcagcgc cgcgaggccg aggcgcgctg gccgggcctg
    90901 tcggggcgca agcttatcaa cgagacggtg cggcgcatga tccacctgat ggtgatcgac
    90961 ctcatcgagc agacccgcgc caacatcgcc gccgagggcg tggcgacgct cgccgacgtc
    91021 catgccgcgc cgcgcctggt ggcgtattcc gatgcgctgc tgccgcccct gcgcgagctc
    91081 aaggtcttcc tgcgcgacaa gctctatcgc cactaccagg tgctgcgcat gaccaacaag
    91141 gcgcgccgca tcgtcggcga cctgttcacc gccttcaccg acgaccccca catcctgccg
    91201 ccgcagtacc aggcgatggc gcgcgaggac aagccgcgcg ccatcgccga ctacatcgcc
    91261 ggcatgaccg accgctacgc catgaaggag caccggcggt tgttcgctgt gggggagatt
    91321 tattgaggcg tgagacgtga gacgtgaggc gtgaggtggg tctcctgctt gacaccggga
    91381 cgcatcgcca ccggcaccgc cgcgttcgcg cctgccggcg ctcctacagg aaccgacgcg
    91441 gccccgatgc aatgtaggag cggcggcagc cgcgaagcag gcgttcagcg accgccgccc
    91501 atcgccaccg gcaccgccgc gttcgcgcct gccggcgctc ctacagaacc gacgcggccc
    91561 cgatgcaatg taggagc
//
LOCUS       DAOTIN010000002        77379 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_273_length_77379_cov_9.755173, whole genome shotgun sequence.
ACCESSION   DAOTIN010000002 DAOTIN010000000
VERSION     DAOTIN010000002.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 77379)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 77379)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77379
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_273_length_77379_cov_9.755173"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1079)
                     /locus_tag="P5537_00440"
     CDS             complement(<1..1079)
                     /locus_tag="P5537_00440"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HRV76538.1"
                     /translation="MKKIVIAPDSYKESLSALEVAQAIAAGFRQVFPAAEYVLVPVAD
                     GGEGTVDAMVAATGGHKEVVAVRGPLGEPVEAFYGLTGDGATAVIEMAAASGLALVPP
                     DRRNPLVTTSRGTGELIRAALDAGARRFILGIGGSATNDGGVGMVQALGARLLDAQGR
                     ELGPGGGALADLDRIDVCALDPRLRECRIEVACDVDNPLTGARGASAVFGPQKGATPE
                     MVQVLDANLARLARIVGRDLGVAVDTVPGAGAAGGMGAAMLAFFGATLKPGIEIVTAA
                     VDLDTHVRDADLVITGEGRIDFQTVHGKTPIGVARVAKRHGKPVIGIAGSLGAEVGVV
                     HAHGIDAVFSVLGKPCTLDEALRDAA"
     gene            complement(1205..2344)
                     /locus_tag="P5537_00445"
     CDS             complement(1205..2344)
                     /locus_tag="P5537_00445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004356934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar diacid recognition domain-containing
                     protein"
                     /protein_id="HRV76539.1"
                     /translation="MFLLDASLAQSIVDRAMQILRTNVNVMDERGLVIASGDRARLGT
                     RHEGALLVLAQGRAVEIDEAVAQRLHDTRPGINLPLRAEGRVVGVVGLSGEPDAVRQH
                     AELVRLAAETMLEQAQWMQMLARDQRLREELVLQRIGVSPPGAGLDDWARRLGVDLAR
                     PCVALLIEIADAGLAADAVLAAQQRLRRLLAEHEPGLACAPVTLRELAVLMPLPAAAS
                     DLRGRLQALHERLCGEGSGQPCLALGGYFGGDDGLVRSWKSARATLQAGRRHRPQAAI
                     HCYDELTLPVLLAGLGEGWRADELRRPLRRLARHDRDGQLRRTLAAWFAHDMKAALSA
                     GALHVHRNTLEYRLRRIGEITALDLSRLNDCLLLFIGLELDTGEE"
     gene            2482..3864
                     /locus_tag="P5537_00450"
     CDS             2482..3864
                     /locus_tag="P5537_00450"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fumarate hydratase"
                     /protein_id="HRV76540.1"
                     /translation="MTRTETDSLGAIEVPAEAYWGAQTQRSLLHFAIGDERMPLAIVH
                     ALALIKKAAARVHARSGELPADLAERIEQAADEILAGRHDAQFPLVVWQTGSGTQTNM
                     NVNEVIAGRANELAGLGRGGKAPVHPNDHVNRAQSSNDCFPTAMHIAAARAVHDELLP
                     AITELSNGLATQAERHAEVLKTGRTHLMDATPITFGQELSAFVAQLNTSAHAIRATLP
                     AVYELAQGGTAVGTGLNAPPGFAAAIADELAALTGLPLVGAANRFAALAGHEPLVALS
                     GALKTLAVALMKLANDLRLLASGPRAGLAEVKLPANEPGSSIMPGKVNPTQCEALSML
                     ACQVLGNDATIAFAASQGHLQLNVFKPVIAHNLLQSIRLLADGCRSFQRHCVAGLEPD
                     TTRMAEHLDRGLMLVTALNPHIGYDKAAQIAKKAWAEGTTLRAAALALGFTTAEEFDA
                     WVRADNMLGR"
     gene            4104..4322
                     /locus_tag="P5537_00455"
     CDS             4104..4322
                     /locus_tag="P5537_00455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper 2TM domain-containing protein"
                     /protein_id="HRV76541.1"
                     /translation="MKARTLIPALLITFAASGCATWDNLSSREKSAATGAAVGGVAGA
                     VVSNGGILGTVGGAAIGGVIGDQVGKNK"
     gene            4460..6067
                     /locus_tag="P5537_00460"
     CDS             4460..6067
                     /locus_tag="P5537_00460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004356928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HRV76542.1"
                     /translation="MTTTPFPPELLRDVEKRRTFAIISHPDAGKTTLTEKLLLFGGAI
                     QLAGTVKARKSARHATSDWMEVEKQRGISVTSSVMQFEYQGHTINLLDTPGHEDFSED
                     TYRVLTAVDAAVMVIDAAKGVEAQTIKLLEVCRLRNTPIITFVNKLDREVREPFELLA
                     EIEDVLKITCAPVTWPLGMGKAFRGVYHLLQQQVLTFTPGEERRSDGEIIKGLDNPEL
                     DKRFPMEVGQLRDDVELIDGASPPFDLDDFLAGKQSPVFFGSGINNFGVQEILQSLID
                     WAPPPQARDGGSRMVQPAEPAFTGFVFKIQANMDPKHRDRIAFFRICSGRYSAGMKVR
                     HVRAGREMKLANVLTFMANERVIMEDGVAGDIVGIHNHGQLQIGDTLTEGENLGFKGI
                     PYFSPEMFRAARLRDPLKSKQLQKGLQELGEEGAIQVFELEGGQMLLGAVGVLQFEIV
                     AQRLKDEYKVDAIFEPADIHTARWLTFPDDVTRRNFEREQALRLGKDIDGNPVYLATS
                     RYNLEVTAEKWPKVTFHATREHGEVLG"
     gene            complement(6159..6368)
                     /locus_tag="P5537_00465"
     CDS             complement(6159..6368)
                     /locus_tag="P5537_00465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004356926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76543.1"
                     /translation="MKNCGDSDTEPTRWALWRLDDNDNRFVVGVFARREEAEAAARAF
                     EAHGHKQTYWVEAVSAPAAPRPTRS"
     gene            complement(6430..6954)
                     /gene="hemG"
                     /locus_tag="P5537_00470"
     CDS             complement(6430..6954)
                     /gene="hemG"
                     /locus_tag="P5537_00470"
                     /EC_number="1.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004356925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="menaquinone-dependent protoporphyrinogen IX
                     dehydrogenase"
                     /protein_id="HRV76544.1"
                     /translation="MRLLIIYSTIDGHTLEICERIAAIVRDAGHEAELAEVAAVSAAE
                     LEACDRVVIGASIRYGHHRPAVKAFIDRHQAALEARPNAFFSVNAVGRKPHKRQADTN
                     PYVRKFLAQIRWKPQQIAIFGGKIEYPRYGFFDRNMIRLIMWITGGPTDPRSVTDFTD
                     WAEVEAFARRFVHG"
     gene            complement(7075..7455)
                     /locus_tag="P5537_00475"
     CDS             complement(7075..7455)
                     /locus_tag="P5537_00475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004356923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76545.1"
                     /translation="MLKPSHTVRALLAAVALATASGAALAQNFMKDKAEVEKLLTGAT
                     FIGVYLRTEAAYTLQFGTDGTLTDTTGAKARWWVDDQARYCREWLDGKLKGNTGCMNL
                     ELEDGQVALYSEGKKVVEGIVTGK"
     gene            complement(7534..8403)
                     /locus_tag="P5537_00480"
     CDS             complement(7534..8403)
                     /locus_tag="P5537_00480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004311854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HRV76546.1"
                     /translation="MIMSEGLAIAIAVLVFVVITIAKGVRLVAQGEEWVVERLGKYHA
                     TLRPGLNILIPYLDRVAYKLVTKDIILDVQEQEVITRDNAVILTNAIAFVKVTDPVKA
                     VYGVTDFSEAIRNLIMTTLRSIVGEMELDEALSSRDKIKARLRESIADEAVDWGLTVK
                     SVEIQDIKPSESMQRAMEMQAAAERERKAAVTKAEGAKQAAILEAEARLESAKRDANA
                     QVMLAEASAESIRRVTAGIGDQAGPMMYLLGEKYIGALEKLGESGSAKIVVMPADLQE
                     TLRGLVGRLGARG"
     gene            complement(8434..8889)
                     /locus_tag="P5537_00485"
     CDS             complement(8434..8889)
                     /locus_tag="P5537_00485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004356919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HRV76547.1"
                     /translation="MNDTLFLEWWHWEIAGIALVLLELALPSFFIIWFGLGAMLTGFV
                     LLAVPDLVLSRQIAAWIIASMAMTVLWFSFARRSRVKTLIGTAAGEVIGEVGLLVSAV
                     APFERGKVRFQRPVLGADEWACVAETAIAAGERVKVVSVEGSYVKVTKA"
     gene            complement(9636..10634)
                     /locus_tag="P5537_00490"
     CDS             complement(9636..10634)
                     /locus_tag="P5537_00490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004356916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-associated protein RdgC"
                     /protein_id="HRV76548.1"
                     /translation="MWFKNLQVYRLPANWDMSVERLEEQLAKKPFHPCGSQDMESRGW
                     LSPLGNEVLAHAVGGQWLVCLGFEHRLLPSAVVKQEADERAEELAEQQGFKLGRKQLK
                     ELREQVTQELMPRAFTRRRRMFAWIDPVNGWLVVDAASQSKAEDMLEQLRHTLDSFPL
                     TLLRTELSPMSAMADWLAGGEAPDGFTIDQDCELRSVAEDKAAVRYARHPLEGDDVKG
                     HLEAGKLPTRLALTFDDRISFVLTEKLEIKRLDFLDIVRDQVGEADKDDAEALFNAEF
                     ALMTGELAHLLPAVVAALGGELAGTPAQTNAVSAELPRLQADKRVAQAVTADDPPF"
     gene            complement(10812..11279)
                     /locus_tag="P5537_00495"
     CDS             complement(10812..11279)
                     /locus_tag="P5537_00495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004311859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005488 - binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SRPBCC family protein"
                     /protein_id="HRV76549.1"
                     /translation="MKFEHLIEVNDLANPLLTPLTREELWFGLLCRAEDARAFLPGLE
                     ACHVVERGEAGLVRDLHFGHAVIRDRVSFDTLRWIRFESEANAQHAGGSLTITIEEPE
                     PGALFLRFAYHTSLPDQGEDARYAEFVRSAYHQSDLDTVRIIRMIAESGGLQQ"
     gene            11407..12153
                     /locus_tag="P5537_00500"
     CDS             11407..12153
                     /locus_tag="P5537_00500"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004356912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HRV76550.1"
                     /translation="MRTMQLERLLHAQGFGSRKECRALIRAGYVSIAGEVCDDPNADF
                     DPGSRDGSPGLEFTVDDQPWRFRAQAYVVLHKPAGYECSQKPTFHPSVFTLLPPQLLA
                     RGVQCVGRLDQDTTGLLLLSDDGQFIHQWSSGKKRTPKVYEIVLKHAVEQDFADRLVA
                     GVELHDEPAPIAAAACELVGPTTLRLTICEGKYHQVKRMVGAAGNRVEALHRSRVGGL
                     ELPTGLAPGQWRWLEAEDLARLADYADPEA"
     gene            complement(12373..13329)
                     /locus_tag="P5537_00505"
     CDS             complement(12373..13329)
                     /locus_tag="P5537_00505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004311863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76551.1"
                     /translation="MPVRSLLSIALLLALPSLAIAQPAANPVSPQAAQEQDLLEQSRT
                     QVRGFSFWLGETVNDWFGDRPFEEGGKVTHGRLGLRNLWRQDEGWDTNVRFRARFDLP
                     NLRDKAYVFIGRQNERELVTDQAEAFTREQLLLEERRKEDQTGFAGVGLALRKNLDFR
                     VGVRGGMKFYTQARYRKQWALTEQDRIEFRETIFWNNKDKFGSTTALDYEHAFTPTLS
                     LHWQNATTISEKTDDFAWGSSLGLFKRFGDDRILSGEMVVTGETGAEENVDEYGVRMK
                     WTQPVYREWLIGEFIVGHYWPQREDRERERAWAAGVNLEMRF"
     gene            13348..13575
                     /locus_tag="P5537_00510"
     CDS             13348..13575
                     /locus_tag="P5537_00510"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76552.1"
                     /translation="MGLKASSVVYGRSHGHIMPAVSCDGQAHWAEPWGPGLFFCFSID
                     LNNKEVNSGAFLVDKSPKLMSIATSIGLKSG"
     gene            13685..14872
                     /gene="earP"
                     /locus_tag="P5537_00515"
     CDS             13685..14872
                     /gene="earP"
                     /locus_tag="P5537_00515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0106361 - protein-arginine
                     rhamnosyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P maturation arginine
                     rhamnosyltransferase EarP"
                     /protein_id="HRV76553.1"
                     /translation="MHSSSSAARPRWELFCQVVDNFGDIGVCWRLAADLARRGCGSVR
                     LWVDDWEALRRICPAANAVDERVGGSVEGVELRRWTTAFVPLVPGEIVVEAFACELPP
                     AQLEAMAALQPAPVWINLEYLSAEAWVAGCHGLASPHPRLPLVKHFFFPGFDAGSGGL
                     LREADLLARRDRWCSQPEGAAGWFAARGIKSSRDALRVSLFAYEQPDLPALFEAWADG
                     DREVLVLVPESRVLGDVRRALGRECLQVGDRVERGALVTCVLPFTDQAGYDVLLWACE
                     LNFVRGEDSFVRAQWAARPFVWQIYPQADAAHHDKLEAFLARYLQGLPAAEADALARF
                     WRAWNGYASDRSSLAEAWPAFAAAVPALELHARRWCDAQAALPDLATALDAFCSHIEH
                     AAR"
     gene            14938..15495
                     /gene="efp"
                     /locus_tag="P5537_00520"
     CDS             14938..15495
                     /gene="efp"
                     /locus_tag="P5537_00520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HRV76554.1"
                     /translation="MKTAQELRSGNVVMVGSDPLVVQKAEYNKSGRNAAVVKMKFKNL
                     LTGAPSESVYKADDKFEVVVLDHKEVTYSYFADPMYVFMDADYEQYEVEADNMTDALK
                     YLEDGLQCEVVFYNGKAISVELPNSVVREVVYTEPAVKGDTSGKVMKPAKISTGFELP
                     VPAFVEIGDKIEIDTRTDEYKNRVK"
     gene            15639..16208
                     /locus_tag="P5537_00525"
     CDS             15639..16208
                     /locus_tag="P5537_00525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76555.1"
                     /translation="MNASRLLLALAASLLATACAPEPETQPKAEPAVPSPEAPRSEAA
                     EARREAAEAAREAVQKAGEAARKIGEAGSAAVEAAVRTAAEKAASELAKDSSDDSVAG
                     GLHQAPNEDRGGDGRPAETVRDARQAAEQAAHRIAEATRDAAERLREVGKGALESMRA
                     RTELPTQEAAPVEERSAVPIEDGKEPAGR"
     gene            16238..17386
                     /locus_tag="P5537_00530"
     CDS             16238..17386
                     /locus_tag="P5537_00530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin family protein"
                     /protein_id="HRV76556.1"
                     /translation="MASASVFRTLLLLACLLFTQASPAADAAMAAPALDLPAPGQLHV
                     YVREGCPHCAEAKRFLASLAGSRPGLQVVLREVDRDPAARDALVAISEAVGAWPPGVP
                     TFVYGGRVLVGFDDAEHVGAELLRLLDEAPPPPRDRVESSLFGTLSASELGLPLFTLA
                     LGLLDGFNPCAMWVLLFLLSLLVRLQDRRRMAMVAGTFVLASGAVYYAFMAAWLNVFL
                     LVGMTAALRVGLAVLAMLIGLINVKDFFAFRRGVSLSIPASAKPGIYARARAILKAES
                     LPASLVAVAALAVVVNFVELLCTAGLPAIYTAVLTSQGLSPLAHYGYLGLYILAYIAD
                     DALMVGTAVLALGSGKLTESGGRLLKLLSGVVMLALGVVMLLRPQWLM"
     gene            complement(17396..19066)
                     /locus_tag="P5537_00535"
     CDS             complement(17396..19066)
                     /locus_tag="P5537_00535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76557.1"
                     /translation="MAEPAAELTVKHFRLALLWPLRLLTGAGVLGPQQRPWQVLRDLG
                     EASPWREVEHDLEVEGSVFQERHYNEFVTFLPYVQQLLYGEGRAQHSDSADAGPAMRV
                     FRRRDIARLRVAAREGDTPVTLDVVHVHLYFFFDIDVVILNVEVAGGDLPLSEVQELM
                     YRIGRAYPSGWDEHGRALHSLAVAELLGRDGSVLARTDAHEREAFMAHVSRHRAPRIA
                     SHWAWLMQPLASAYSEQPGALRYRQIEYHRMPLTAYLALDDPLALTRQDFVRLGLVTG
                     AGPRDAEREGAGNTLPYGNPHLDDFERRYCYDRFWSASGAAPWTRYLCSGHALVVVGD
                     ARSAYFTDRERGVLAQFRHQHFLLFLIAHFQKAALLMFSERLVEALKRLHVADPASVR
                     RFKRAIRASFEGFLRFTHRYWFHDIAEQAQTRALFRMSTAHLGTDALYAEVKERTADM
                     NGYLEADSLRRQANTVVRLTVVTIFGLIGTITTGFLGMNLLAEAESPLSERLLYFALV
                     FAVSTGLTMYTMVKSKRLSDFLDAVSDERLSAWNKLAALAAVWRRGTD"
     gene            complement(19144..19515)
                     /locus_tag="P5537_00540"
     CDS             complement(19144..19515)
                     /locus_tag="P5537_00540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin family protein"
                     /protein_id="HRV76558.1"
                     /translation="MTHVVTEACIRCKYTDCVSMCPVDAFREGPNFLVIDPEECIDCT
                     LCVAECPVDAIVPEDELTAAQREYLALNATLAKAWRRIVEAHPALPDANTWAKVTEKR
                     KWLETSAGVADATTDLPGTAP"
     gene            complement(19512..19868)
                     /locus_tag="P5537_00545"
     CDS             complement(19512..19868)
                     /locus_tag="P5537_00545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemerythrin domain-containing protein"
                     /protein_id="HRV76559.1"
                     /translation="MKRHSRLAQLSREHHTALRLGRHLLAGGAQAELDAELPGLEAHF
                     AEEERDLLPLLDTDRHLALAERLRAEHAQLRLLFAAALRGRDEAQAGQALIDHVRFEE
                     RELFPVLETLFEEARP"
     gene            19990..20484
                     /locus_tag="P5537_00550"
     CDS             19990..20484
                     /locus_tag="P5537_00550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004336060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HRV76560.1"
                     /translation="MNITQHTDYALRVLMYLGAVPERRVTIKEVAERFDISRSHLMKI
                     VTELVAKGFVDGARGKGGGLRLARAASEIGLGDVVRQLEPSLALVECFGTQSHCVLDP
                     ACRLKGALDSALQAFLAALDRVSLADLVGSDARLHAALGLQAAARATVPITIVHPPAG
                     RERR"
     gene            20668..21243
                     /locus_tag="P5537_00555"
     CDS             20668..21243
                     /locus_tag="P5537_00555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1282 domain-containing protein"
                     /protein_id="HRV76561.1"
                     /translation="MSSLHLPPMLWSSDAAWTELSRRPPSLATLVFGVALPAAMLPPT
                     MLSHATDVGSAHYLPALSASAWQFVEFALFAAQVAGFLMIRWLIGAVAASHGVRASAR
                     DACLLATVSLLPLWLSSFALLQDGTLAVLVLPLLAIGASVALLKRGVRCMLGVREEIV
                     ALEIGIVAIHCGVLAWAATMAVFLVPGLPAL"
     gene            complement(21301..21996)
                     /locus_tag="P5537_00560"
     CDS             complement(21301..21996)
                     /locus_tag="P5537_00560"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008177 - succinate dehydrogenase
                     (ubiquinone) activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase iron-sulfur subunit"
                     /protein_id="HRV76562.1"
                     /translation="MRLNIYRFDPERGAPPRMQAYEVQPEAGDKKLLDLLMRLRVQDD
                     SLSFRRSCREGVCGSDAMNINGRNGLACLTALDGLKEPIVLRPLPGFPVIRDLIVDMT
                     QFFAHYHSIRPWLINDEPLPERERLQTPAERERLDGLYECILCACCSAFCPSYWWNPD
                     KFIGPSGLLQAYRFIADSRDTATAERLDFLDDVYRLYRCRTIMNCTEVCPKGLSPSHA
                     IERIRLALLRRSS"
     gene            complement(22014..22346)
                     /gene="sdhD"
                     /locus_tag="P5537_00565"
     CDS             complement(22014..22346)
                     /gene="sdhD"
                     /locus_tag="P5537_00565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045282 - plasma membrane succinate
                     dehydrogenase complex [Evidence IEA];
                     GO_function: GO:0000104 - succinate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase, hydrophobic membrane
                     anchor protein"
                     /protein_id="HRV76563.1"
                     /translation="MRLFDGQRAWVVQRISALLLLVLAVLALPFASPLDFSAWRAFAG
                     GVLGGPLIALLFGALCAHAWVGLRDIVLDYIQPRGLRLAVLSLIAVVLLGVLVRVLLS
                     LAAAALST"
     gene            complement(22343..22798)
                     /gene="sdhC"
                     /locus_tag="P5537_00570"
     CDS             complement(22343..22798)
                     /gene="sdhC"
                     /locus_tag="P5537_00570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045282 - plasma membrane succinate
                     dehydrogenase complex [Evidence IEA];
                     GO_function: GO:0000104 - succinate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase, cytochrome b556
                     subunit"
                     /protein_id="HRV76564.1"
                     /translation="MVYGSGKRCSAATGGGSNCPGAHMDRHPRRLPVFLKLAQIRFPI
                     GAIASIAHRVSGVLLFIALPVVAVLLDTSLRDEAGFASVRDLISSPLAVVAAGVLVWA
                     LVHHVLAGIRHLLMDVGIGGELERARASARLVLIAAPALAVFLLFWGLS"
     gene            complement(22834..>23747)
                     /locus_tag="P5537_00575"
     CDS             complement(22834..>23747)
                     /locus_tag="P5537_00575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="YbfB/YjiJ family MFS transporter"
                     /protein_id="HRV76565.1"
                     /translation="ALPWVGMALRGSAGVFSAWVLVCASSWCLPELARRHATSLGGWI
                     YTGVGLGIAATGVLTWLGGAQAASVLWVELGLLATVGAVQVMRRVRGQPAVAPVAGVA
                     GAPRSAAPAVAGGNLGVVLCYSAFGFGYIIPATFLPTMARQLVSDPLVFGLTWPIFGM
                     AAVLSVAFAAHRLHGWPRRKVWAIAQGVMAVGTLLPLLQPALWVLAASAVLVGGTFMV
                     TTMAGLQLARERMPANPTPLLARMTTGFAAGQIAGPLLVRLVGDTRVAGLDALGVASA
                     SAGLLLAITSIWLWREGSGSASDARSS"
     assembly_gap    23748..23847
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<23848..24197)
                     /locus_tag="P5537_00580"
     CDS             complement(<23848..24197)
                     /locus_tag="P5537_00580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbfB/YjiJ family MFS transporter"
                     /protein_id="HRV76566.1"
                     /translation="MKRHSSSSLSPRSIVFIGLVALAIAMGIGRFAFTPMMPLMVRDG
                     SLDAVTGTEWATANYVGYLLGAISASWFARSPRLGLQVGLVGVAATTLAMAWGNAALP
                     WVGMALRGSAGVFSA"
     gene            24449..24721
                     /locus_tag="P5537_00585"
     CDS             24449..24721
                     /locus_tag="P5537_00585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004371118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family ribbon-helix-helix protein"
                     /protein_id="HRV76567.1"
                     /translation="MATSLKIDDALKSRVQHLAAQRRRSAHWIMLEAIQQYVEREEAR
                     ESFTQEALASWAAYKETGRHLSGQEVRTWLNTWGTADESAVPKCHK"
     gene            24748..25002
                     /locus_tag="P5537_00590"
     CDS             24748..25002
                     /locus_tag="P5537_00590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018158495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HRV76568.1"
                     /translation="MERCRRFLVARAPEAARRAGQAIARQLLLLETAPDIGRPLPEIP
                     ELRELVIAFGDSGYVALYRHEPADDAVYVLAFRHQKEAGY"
     gene            25016..25789
                     /locus_tag="P5537_00595"
     CDS             25016..25789
                     /locus_tag="P5537_00595"
                     /inference="COORDINATES: protein motif:HMM:NF014442.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006306 - DNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HRV76569.1"
                     /translation="MLLHGVKDSEFEIFHGDTLLNEWDMLRETNPARMPKFDAVVANP
                     PFSYRWEPSEALGEDVRFKNYGLAPKSAADFAFLLHGFHFLKQDGVMAIILPHGVLFR
                     GGAEARIRTKLLKDGHIDTVIGLPANLFFSTGIPVCILVLKKCKKPDDVLFINAAEHF
                     EKGKRQNQLLPEHIDKIIETYQFRKEEARYSRRVGLAEIEKNDFNLNISRYVSTAEAE
                     EEIDLAAVHAELVSLEQKRKAALDKHNAFLKELGLPMLP"
     gene            26084..32365
                     /locus_tag="P5537_00600"
     CDS             26084..32365
                     /locus_tag="P5537_00600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit A"
                     /protein_id="HRV76570.1"
                     /translation="MPASTPRYTPIDAPASIADAIRIRGARQNNLRNLSLDLPLNRLT
                     VVTGVSGSGKSSLVFDTLYAEGQRRYVETFSPYARQFLDRMDKPQVDRIEGVPPAIAI
                     DQTNPVRTSRSTVGTMTELADHFKLLYARAAHLHCRCCGKPVRRDSAVSIAADLRARA
                     AAAGDPRLVVCFPVTVPSSFREAEVTGLLAAQGYTRIQERLAGAGAEGQDVLQVVQDR
                     FRASNAEDARLAEALEAALQRGHGRLAVYASGEGVKAAATEGTPGEAVWRYSSGLHCA
                     DCDIHYSEATPGLFSFNSPIGACETCRGFGRVIGVDFGLVVPDESKTLAEGAVKPWQT
                     ESYRECQQDLEKMAKKYGVAMDIPVRDLPPEHRQWLFEGDPKWKNWDSSWPRYWYGVR
                     HFFDWLETKAYKMHIRVLLSRYRSYTECPACHGARLKPDALLWRLPTSGEASGRSGGS
                     REQGVDDGCAFGAAVFAAAAAPTGGAPSVREDGEVGAANAVSEASSAGEDAEVGAANV
                     AAGAPSAGEDGEVGAANAAAGAPSVREDGEVGTANVAGGAFNVGGANVLAGASIVGAE
                     APVGVALAGSVARGSGLAIHELMALPVDRIRDAIAALALPGAADEATELVLGEIRSRL
                     TYLADVGLGYLTLDRQSRTLSGGEVQRINLTTALGTSLVNTLFVLDEPSIGLHPRDIG
                     RILGVMTRLRDAGNTLVVVEHDPQVMVAADELLEIGPGPGERGGDIVARGTPAEIAAN
                     SDSVTGPWLAGKKRIDVDRPPRPVDAATPRLKLVGARQHNLRDLTVGFPLLRLTCLTG
                     VSGSGKSTLIQDVLFPALAKHFGEATESPGIFDRLESVDNLRGVIMVDQSPIGKSSRS
                     NPVSYVGAWDPIRALYAALPEAKQRGYTPGTFSFNAGHGRCPTCTGSGFEHVEMQFLS
                     DVWLRCPDCDGKRYRPEVLELQWNGLSVADVLALTVHEALDVFREHPKVLAALAPLAD
                     VGLDYLRLGQPVPTLSGGEAQRLKLAGHLAEAAQRKPVRKASAVDKFGSKAGDKANGL
                     AVRAGRGTPGGVSWLTEPAEPGLLFLFDEPTTGLHFEDVAKLLGAFDKLLQAGHSLIV
                     IEHNLDVIAASDWIIDLGPEGGEGGGAIVVEGPPEVVRTHASSHTGAALRDYAEALKE
                     IGDRPQFLGHPVPVPGERSCRSGGSREPASANDGAAVGAMFAAAAAPAGGLVAAEPRV
                     EYRPVAAPAIEIRHAREHNLKNVSLQIPRDQFTVITGLSGSGKSTLAFDIVFGEGQRR
                     YLESLNAYARQFVQPASRPDVDGLFGIPPTVAIEQRTSRGGRKSTVATLTEIHPFLRL
                     MYVKLGTQFCPDCNVPVTPQSFEAIVAQVQRELRGASVEVLAPLVVNRKGLYTDLAKW
                     ARGKGHAQLRVDGEYLPTNKWPRLDRYKEHNIELPTGMVVVQPEHEATLREFVRQALD
                     IGKGVIKVLEIGKLGAQPITFSTLRACPSCGTGFPEPDPRLFSYNAKHGWCPKCYGTG
                     LKTAARIEDPDALDLGDAEEVIVSDEPCPACEGARLNPVARAVRFRELGLHQLAAQPV
                     DKAAGFFADLALNERETDIARDLVSEIRGRLAFLQHVGLGYLALDRAAPTLSGGEAQR
                     IRLAAQLGSNLRGVCYILDEPTIGLHPRDNRLLLDTLEALRDRGNTLLVVEHDEDTIR
                     RADHVIDLGPGAGVRGGRVVAEGRIDDLLAAPESATGECFRHPLQHPLRPRRAVALEN
                     PAIRIEGANLHNLRGVDVRIPLARLTVVTGVSGSGKSSLARDVIHANLRARLGDPEAT
                     RARRRGQAQPEAVDQPLVGCAAMPGWHQVGRVLEVDQTPIGKTPRSCPATYVGFWDAI
                     RKLFADTFDARTRGWNASRFSFNTGAGRCPVCDGAGQTTVEMSFLPDVKTPCEACGGA
                     RFNPETLSVRWKDRTVAEVLAMPVDEAVDFFSAHPAIAHPLQLLQDVGLGYLTLGQPS
                     PTLSGGEAQRIKLVTELAKVRRRPGDADDTGGVPLPADKHSLYVLDEPTVGLHMADVD
                     KLIRVLHRLTDAGHTVLVIEHDLDVMAEADWLIDLGPEGGDGGGRVVAEGPPEVAMAT
                     PGSHTGRHLREFLAQRKVG"
     gene            32512..33198
                     /locus_tag="P5537_00605"
     CDS             32512..33198
                     /locus_tag="P5537_00605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002932194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b/b6 domain-containing protein"
                     /protein_id="HRV76571.1"
                     /translation="MNTRKIRVWDLPTRLFHWLLVVLVLAAYVTGQIGGSMIEWHGRA
                     GVAITGLLAFRIVWGIVGSTYARFADFVPTPGRIGSYLRGQWNRPGHNPLGALSVFAL
                     LAILIFQAVSGLFSNDEIAFSGPLRELVSSETSERLSGLHRQNYWVILAFVVLHVGAV
                     VFYALVKKDDLVKPMITGVKEVADPAHEPARGGGTVAFIVALAVTAAVLYFATGSFIE
                     PPPPPPPAAW"
     gene            complement(33349..33801)
                     /locus_tag="P5537_00610"
     CDS             complement(33349..33801)
                     /locus_tag="P5537_00610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c"
                     /protein_id="HRV76572.1"
                     /translation="MKKAIALGILSLTLATAASAQVKPEDQIKFRQAGYSFMSWNMGK
                     IKANLEGEYNAQQVQAAATAIAGIAGSGMGALYGPGTEKDIGSLKTRVKPEFFQEMPN
                     VGKLATDFNNAAANLAKVAATGDKAAVQKAFGATGETCKACHDKYRME"
     gene            34074..35696
                     /locus_tag="P5537_00615"
     CDS             34074..35696
                     /locus_tag="P5537_00615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0098561 - methyl accepting chemotaxis
                     protein complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HRV76573.1"
                     /translation="MIRFSDTPIWLRLTGAIWLMMVAAFGSMIVWETRVNRDMAIEQA
                     KDFAGTVNEMTMAGLTGMMITGTVAQRDVFLDQIKELSVVQDLEVIRGEAVSRVFGGG
                     GALEAARDADERLALVEGRSTVRVDHDAEHGEHLRVVIPSLASTDWLGKDCIACHQVP
                     QGTPLGAVSMRISLDKANAAVLAFRNQSAMFAALVSIPLILFIYLFITRFVTRPLDGL
                     NQGLGRIAEGGGDLRLQLPVRGRDEIGRSARTFNDMMGTLSGLVRQVGDSASAVTEAA
                     SRLAADAEAVAESSQRQNESSMGAASAVDEMVGSISAIAEHAEAVRERSHDSLERSRE
                     GQRSLERLVGEVGEVEAAVRQMADAVVAFVDSTQAISRMTSEVREIAEQTNLLALNAA
                     IEAARAGEQGRGFAVVADEVRKLAEKSARSAGEIDQITREVARRSGSVRGALDDGLGH
                     LASSRQMADAVMQVLGAANSLVVEVGEGLDRIAGATGAQRNASESVTARIGEIAGMAR
                     SNNDALAHTVQSARELGELAVRLQESVSRFRF"
     gene            complement(35781..37250)
                     /locus_tag="P5537_00620"
     CDS             complement(35781..37250)
                     /locus_tag="P5537_00620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegQ family serine endoprotease"
                     /protein_id="HRV76574.1"
                     /translation="MRKFLTVTAVALALGTIFPQASVLPAAHAQAAAPSMVSPNRFGL
                     PDFGDLVEQVGPAVVNIRVVQRAAQGTAGENPLANDPFYDFLRRFGVPMPGFPGQPGM
                     GPRARQGIGSGFIVSQDGYVLTNAHVVAGEDGDAELSEVTVTLIDKREFKAKVVGIDR
                     RTDVALLKLDATGLPAVKIGNPDQARVGEWVVAMGSPFGFDNTVTAGIISAKARRLPD
                     ETYVPFIQTDVAINPGNSGGPLFNLAGEVVGINSQIYSRSGGFMGISFAIPIDVAMNI
                     KDQLVSHGRVQRGRLGIAIQNVDKDLAQSFGLPDPRGALVASVEPGSAADKAGLQAGD
                     VVLAVDGRRIDDSAELPRVIGEKRPGTRVKLELWRDGRSREVAATLDELKAETVAGNA
                     PAPSQVERLGEQFGLSARALSAEESARLQLRGGVMVEGADGASARAGLQRGDVILAIN
                     NQPVLSVAELRAQLERAGKRFALLIQRGEARIFVPVRLE"
     gene            complement(37399..39426)
                     /locus_tag="P5537_00625"
     CDS             complement(37399..39426)
                     /locus_tag="P5537_00625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HRV76575.1"
                     /translation="MSLHPHRVALVLLLTASAAWASAENPFFEPLPVVLSASRLAQPL
                     QDSPGAVSVIDADLIAATGYRELARVLRLVPGFQVGQERGNVQWVTYHGLGMDYPVQM
                     QLLVDGRASLTPSFAASAERALPGDIERIEVVRGSNSAAYGSNAFLGVVNITTDDASR
                     TPGTRLKLAAGAPGILDAGVRHAAQAGPLSLRIGAHHEEDDGFDDLYDGRRTDVLNLR
                     ADLRVDATNELGLIAGVAESTHQLGYAGSIFGTAAEREGHKHNRSLHLRWRHTPHEDE
                     EWLLSAYWSGQQMRERWRLDSALNPPPGFQPPPQLGRVQATVGNDAQYTQHNLELEHR
                     LRVSADTRLMWGAEWQRTQDESAFFYHASGRHARNEHRLFSNLEWRAAPAWLWNLGGM
                     IEQLQGDEARFAPRVFLNWQATPRFTWRIGHSRAWRQPVLFERNADVRVIDDLGRPLQ
                     YRQLPNPALRPQRIDASEIGFLGVFGDSRSTLDVRLFRERIDDVIVRSPVPAGQVPPS
                     LFSAMFGSTRWENHAGRVQLNGIETQLHLKPWRGTEFILSHSLIDRDIDDPRIRRNVS
                     PYSASLSWLQRAGAWRSMLSVLRMGPIDAGFSYVPGYNYTVPSYTTLDWSIARSLRVL
                     DQAVEVRLTGINLLGRHQELANRPLQAQAEFAGRPASQVSRQVWMALETTF"
     gene            39555..40511
                     /locus_tag="P5537_00630"
     CDS             39555..40511
                     /locus_tag="P5537_00630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HRV76576.1"
                     /translation="MTLTDLRYLVALAHERHFGRAAEKCHVSQPTLSVAVKKVEEELG
                     IQLFERSASEVKITETGRRIVAQAERVLMEASQIQEIAAAGKDPLAGPLRVGVIYTIG
                     PYLLPRLIPRVHQLAPRMPLIIQENFTARLAEALKRGELDVIIISLPFDEAGVVAQPV
                     YDEPFRVLMPAGHAWNAENEIDPQHLADDQLLLLGAGNCFRDQVLEVCPSCRNIGGLQ
                     RTLEGSSLETIRHMVATGLGVTVLPSSAADEMATQNPLVAVRPFSQPEPSRRVALAWR
                     VTYPRSGAIDVLRAAILDSALPGVTPVGRAMSPASVLRADLR"
     gene            40629..41099
                     /locus_tag="P5537_00635"
     CDS             40629..41099
                     /locus_tag="P5537_00635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Dps family protein"
                     /protein_id="HRV76577.1"
                     /translation="MEIDIGIKEKDRAKIAEGLSRLLADSYTLYLTTHNFHWNVTGPM
                     FNTLHLMFETQYNELALAVDEIAERIRALGFPAPGTYKEFQKLTSMAEPEGVPSAQEM
                     IRLLVQGQEAVVKTARSIAPIADKASDEPTLDLLTQRMQVHEKTAWMLRSLLEG"
     gene            complement(41480..43108)
                     /gene="ipdC"
                     /locus_tag="P5537_00640"
     CDS             complement(41480..43108)
                     /gene="ipdC"
                     /locus_tag="P5537_00640"
                     /EC_number="4.1.1.43"
                     /EC_number="4.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate/phenylpyruvate decarboxylase"
                     /protein_id="HRV76578.1"
                     /translation="MNLTESLLHALVDHGARQIFGIPGDFALPYFRIIEQTGILPLHT
                     LSHEPGVGFAADAAARVQGSIGVAAVTYGAGALNMINAVAAAYAEKSPLVVLSGGPGL
                     GESESGLLLHHQAKTLDSQFRIFQEITCDQVRLDDAARAPADIARVLGNCVRNSLPVY
                     IEIPRDMVARPCAPVLREAPRAVDADALAACVDEILGRLRAARAPVLMAGVEVRRFAL
                     EDKVAELSRRLGIPVVTSFMGRGLLADHDAPLMGTYMGLAGLPEVSALVEDSDGLFLL
                     GVIISDTNFAVSGKHIDLRRTIQALEARVTMGYHTYADIPLDALVDGLLARVAPAEAH
                     FGVDRPAFPHGLLADEATIAPADIACAVNDLMAAHGKLPIASDMGDCLFTAMDIEHTA
                     LVAPGYYATMGFGVPAGLGVQAATGQRPLILVGDGAFQMTGWELGNCRRYGWDPIVLL
                     FNNASWEMLRTFQPESGFNDLDDWGFAQMAAGLGGDGVRVRTRAELKAALDRAITTRG
                     RFQLIEVMIPRGVLSESLSRFVNAVKRLNAAKAG"
     gene            43228..43749
                     /locus_tag="P5537_00645"
     CDS             43228..43749
                     /locus_tag="P5537_00645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002932997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HRV76579.1"
                     /translation="MSTLSIDRHDLALLDALQRSGDATNAVLGEAVHLSASQVSRRLQ
                     RLQEAGLITGYAALLDPAALGLDVIAFAHVVLERHGGVRTEAFEEGVAALPEVLECFS
                     VSGNADYVLRIVAPDLAAFSELMMKRVLRLPGIANIKTDIVLGKVKQTHVLPLEHIAR
                     PSRPRRGVRYSAG"
     assembly_gap    43804..43903
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(44030..46612)
                     /locus_tag="P5537_00650"
     CDS             complement(44030..46612)
                     /locus_tag="P5537_00650"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HRV76580.1"
                     /translation="MSKQLIIAEKPSVAQDIARALGGFTKEKDYFESDDYVLSSAVGH
                     LLELTVPEEFEVKRGKWTFAHLPVIPPHFAVKPIEKTEDRLKLLTRLIKRKDVTGLIN
                     ACDAGREGELIFNFIAQHAGSKKPMQRLWLQSMTAQAIRDGFAHLRAAQDVEGLRNAA
                     ICRAESDWLIGINGTRAMTAFNSKTGGFHLTTVGRVQTPTLAMVVEREDRIRKFKSRD
                     YWELEARFGCAAGEYPGRWFDEKFKKPEGDEHATAFRLWDKAQAEAIRAKCEGKPGVV
                     TEEAKPSTQLSPLLFDLTSLQREANGRFGFSARVTLQLAQALYEKHKVLTYPRTDARA
                     LPEDYLGTVSEVMRTLPDQYAPFANEITKQGWVKPNKRIFNNAKISDHFAIIPTGTLP
                     KSLSDAEYKIYDLVTKRFLAVFYPAAEYQITTRITRVEGEAFKTEGKVLVNPGWLAVY
                     GKEAASDEKDGKPGDPKEGGGPQLVAVKQGETVSTEDIVVKSLQTKPPARFNEATLLS
                     AMEGAGKMVDDEELRAAMAERGLGTPATRAQIIEGLISEQYIHREGRELIPSAKAFSL
                     ITLLKGLGVNALTSPELTGGWEYKLAQMEHGKLSREAFMNEIAEMTREVVERAKRYES
                     DTVPGEFVTLQTPCPKCGGVVKENYKKFACQACDWSTWKIVAGRQFEYDEIETLLREG
                     KVGPLLGFRNKMGRLFNADIVLNEDKQPTFDFGQPKEGEEAEAVDFSAQEPVGACPKC
                     ASRVFEHGMAYVCEKSVGPDRQCDFRSGKVILQQPIEREQMAKLLTEGKTELLKGFVS
                     ARTRRKFSAFLVRGKDGKVGFEFEAKAPKASAKTTAAKGDEAAGEGAAAAAPRKRAPA
                     RKAG"
     gene            complement(46716..47186)
                     /locus_tag="P5537_00655"
     CDS             complement(46716..47186)
                     /locus_tag="P5537_00655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF494 domain-containing protein"
                     /protein_id="HRV76581.1"
                     /translation="MFDILVYLFESYIHADACPEGELLNRKLSAAGFEQDDISEALEW
                     LAGLRRVAREIHPGTAPQAGSVRIYTEEEQALLDGRCRGFLSLLESAGVLGTAHRELI
                     IERAMALADFTITLNRLKVIVLMVLWQQEEPIDTLMVDELLTEEDDWAYEPTLH"
     gene            complement(47271..48443)
                     /gene="dprA"
                     /locus_tag="P5537_00660"
     CDS             complement(47271..48443)
                     /gene="dprA"
                     /locus_tag="P5537_00660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HRV76582.1"
                     /translation="MTVPADDLADWLRLAAVPGVGTQGQRALLAAFGLPGHIFAAGRG
                     ALAAVVGGTAADAVLAAPAHEDIERALAWAGEAGNHILTLADAGYPRQLFDIADPPVL
                     LYVKGDPALLSRPGIALVGARSATAAGEANAGAFARALAEQGLVVVSGLALGIDAAAH
                     RGALAAGTEAAGTVAVIGTGIDRIYPARNAALAREIAAAGAVVSEFPLGTPPLQHNFP
                     RRNRLIAGLAEGVLVVEAALGSGSLITARLATETGREVFAIPGSIHSPLSRGCHRLIR
                     DGAKLVETAEDVVEELRGRLGWPAPVVAPTASARGRQRRGAEPAAPAQPPLQAALALD
                     GETARVLDAIGHDPVDLDTIAARCGLTVDALYAILLPLELEGRLAKLPGGRFQRTT"
     gene            complement(48475..49515)
                     /locus_tag="P5537_00665"
     CDS             complement(48475..49515)
                     /locus_tag="P5537_00665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HRV76583.1"
                     /translation="MKRIIFPLLVAFASLLGVGAHAQSSVRLAADAPDSYTVERGDTL
                     WGISGRFLQEPWRWPEVWRLNRDEIRNPHLIYPGQVILLDRSGPWLSVGRRVGGGSTA
                     DGRLQPRVYNEPIAEALPSIPLQIIEPFLNRPLVVDQPRLDGSATIVATETSRVLTGT
                     GDTIFAKNVGDEAEVWHIYRPARPLEDPRTRAPIAWEAAYLGTARVTERGEPTTLEIV
                     SAVEEIGTGDLMMPSEPPSVFSYAPHAPEFDVEGSIISIYRGVSETGRLNVVALDTGE
                     QDGLERGHVLALYRNRGVAEYRGEDGKESFRLPEKRYGVAFVFRVFERVAYALVMESD
                     GPVTIGDTVRKP"
     gene            49708..50211
                     /gene="def"
                     /locus_tag="P5537_00670"
     CDS             49708..50211
                     /gene="def"
                     /locus_tag="P5537_00670"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HRV76584.1"
                     /translation="MALLPILRYPDPRLHTVATPVARVDDEVRKLIADMAETMYEAPG
                     IGLAATQVDVHKRIVVIDVSEDKSGLMALINPEILERSGEQVCEEGCLSVPGIYEKVS
                     RAERVKVRALNEKGEPFEFEADGLLAVCVQHEIDHLDGKVFVEYLSQLKLGRIKSKLA
                     KKARITA"
     gene            50211..51173
                     /gene="fmt"
                     /locus_tag="P5537_00675"
     CDS             50211..51173
                     /gene="fmt"
                     /locus_tag="P5537_00675"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HRV76585.1"
                     /translation="MAVTATGTGGLSVAFAGTPEFAAQALDAILKAGYAVPLVLTQPD
                     RPAGRGMKLSPSAVKQLALAHGIEVDQPEKLRTDAQRARLADCAPDVLVVAAYGLILP
                     KAVLELPRLGCINIHASLLPRWRGAAPIHRAIEAGDAETGITIMQMDEGLDTGPMLLR
                     RALPIAADDTTASLHDRLAALGGDCIVEALAALQCGQLSPTPQPAEGVTYAAKIGRAE
                     ADIDWSRPALEIERAMRAFDPFPGAVSTLHDTAVKCWKAQVVAGEGEPGRVLAVDADG
                     IVVACGRDALRCTVLQRPGSKRLPAGEFLRGFPVSVGERFASLA"
     gene            51264..52103
                     /gene="htpX"
                     /locus_tag="P5537_00680"
     CDS             51264..52103
                     /gene="htpX"
                     /locus_tag="P5537_00680"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HRV76586.1"
                     /translation="MFGNWIKTTILMAGIVALFGAMGAAIGGQQGMLIALVMGGAMNV
                     WAYWFSDKMVLKMYKAREVDAASSPYLYNMVAELARRAELPMPKVYIIDEAQPNAFAT
                     GRNPDNAAVAATTGIIRMLSERELRGVMAHELAHVKNRDILISTISATIAGAISMLAN
                     FGMFFGGRDGEERPNPIVSIAMMILAPLAGMLIQMAISRTREFGADRGGAEISGDPDA
                     LASALGKIDAYARGIPMHTAEQHPETAQMMIMNPLSGGGLRGLFSTHPSTQERIARLQ
                     AMR"
     gene            complement(52117..53268)
                     /locus_tag="P5537_00685"
     CDS             complement(52117..53268)
                     /locus_tag="P5537_00685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002932971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HRV76587.1"
                     /translation="MDTEPVDLFYSYAHEDEKLRDELDGHLALLRRKGVIRPWHDRGI
                     VPGQQWDEAIDRELSTADLILLLVSMDFLNSDYIWGKELATAIERARRGDASVIPVLL
                     RAVDIEDAPFAHLQGLPTDLRPVTSWPNRDEAWTDVAKGIRRAVEAIRQRWASAPPPA
                     PPPPSAPSAPRSSDLGTAVASAPLPEEAMHSPEMARPALKMAAAEDARTDALLQRAIG
                     AFADELAFAARIKGVEGIASGEAEGLAAALIDMPEQKRVLWVDDQPDNNRHELAALAK
                     LQVEVVSVHSTAEALERLDADEDGFDLVVSDWDRPEPLDGAASAGLKLLGVLAARPRR
                     PPVIFYHAEFAPALRAARRETLLRAGAFGEAVRPGELLALIRSAFASSD"
     gene            complement(53353..55035)
                     /locus_tag="P5537_00690"
     CDS             complement(53353..55035)
                     /locus_tag="P5537_00690"
                     /inference="COORDINATES: protein motif:HMM:NF012235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HRV76588.1"
                     /translation="MSPLPRIAADGRGARIGLIAVLALGQACAAAWAAVAMRAVFAAL
                     HAADGAVPWAALGGIAGAGIAIALLKVLERIQAERVGQAYAASVRATLYRHLSRFAAP
                     ALAKRRTGALALRFVGDLAAVRGWVSHGIARLISAGIVLPVSTSVLFCLAPGFGLAVA
                     APLLAGLALMAIAGVGLGPAHDRLRRRRARIAADMSERVAHAPQLHVIGRSGQELARL
                     ERNTARLLAAALARMRRSALLRALPDAISGAAAAALLLTALQHGLPAATTAAGLATLA
                     LMIQPLRELGMVWDRHRAWQLARRKAERLLATPGLKRRAASVPPQFGNAPPALSFERV
                     GLTEAGRRFDACAEPGQRIAVVGASGAGKTTLLNLAAGLDRPARGRVRIDGIAPTDLP
                     LAQRRRMFAHVGPQSPILAGSLRRALSLGLAPRPCDERLLAVARDFGLGGTIARLGGL
                     DGRVAENGRDLSSGERSRLLLARATLAAPRLLLIDASEGLLDPAGRHALRRLLRNIGA
                     TVLLVTQDERLAREMDAIWFMHSGRVVAAGPPAAVLDGEGAGAGFFAQREAA"
     gene            complement(55055..56146)
                     /locus_tag="P5537_00695"
     CDS             complement(55055..56146)
                     /locus_tag="P5537_00695"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1611 domain-containing protein"
                     /protein_id="HRV76589.1"
                     /translation="MSPAPNPTARTAIAVSPLALAAQAKWAFSTRRVRQDRASQLLAD
                     LAQARPGDLVLGRIVRIGFQKRLQLASGRPADLYTGDLVVMACGARYAPDQFEGLAEL
                     DADEVDILAAGGVLGRMRERNAKVAAPTRVAPLGLLADAAGKVINVGDHALPPLQAPT
                     GMTVIGVVGASMNSGKTTASASLAHGLQRAGFEVAAIKATGTGAFGDYNSFVDSGARF
                     VGDFTDVGMVSTYNEPLERIEAGLDTLLAHAAAAGCEIAVVELADGVLQQETAALLRR
                     PVVRDHFAGLMFAAPDALAAVGGCAVLNAIGLEAFALTGTLSLSPLGAQEAEAATGLR
                     VLGRDELLDPAHASALLAGLRAPALKAAA"
     gene            complement(56200..57063)
                     /locus_tag="P5537_00700"
     CDS             complement(56200..57063)
                     /locus_tag="P5537_00700"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HRV76590.1"
                     /translation="MKNLPKQSLPPAHDTLHGFHIVWRRAHGRNGLACWLAIPHQRRA
                     DTPALVAIHGIQRGAEEMARSFAARAAAEGRVVIAPVFDEAGWTGYQRVVQRRRADLA
                     LIALLDELALEGLVGKRPFTLFGFSGGAQFAHRFAMLYPHRIDHLIAAAAGWYTLPDR
                     HSVFPYGLGAESGRQAWGPKFGAALDRFLQLPVSVLVGTLDNLPDETTRSTPELDRRQ
                     GRDRLTRARTWTRALTQAARARGLEARFRLHTLADCGHRFIDCVRDGGLVDHVFAPPV
                     PLDACTTALAA"
     gene            complement(57158..58150)
                     /locus_tag="P5537_00705"
     CDS             complement(57158..58150)
                     /locus_tag="P5537_00705"
                     /inference="COORDINATES: protein motif:HMM:NF013625.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding domain-containing protein"
                     /protein_id="HRV76591.1"
                     /translation="MKTPIPAVGIAASALFGLGGCATLVNDQASDYRSTVNPVMTEHS
                     LALSCLGELIDRSGKPVLTVFVDDVPDTTVPRRFDERRLSSGGAWWLHTAIDRLGTDK
                     VRSADADRTRPRGNHIVLEGAWTQDDADVGRGGADASGRRRTGTGLFDLGFGFERRTD
                     LIAGDFMSSRGGHVLHASAISVAVNAADASFGLRIQDGRNTFGIELGKRSNDGPQFAQ
                     RRIAEAAVMVHVARAFDVDYAPCIELSSASPASYAASVQAYGRMLPDDRHRAVQQALA
                     RAGHPAGAADGVWGEQSARALMRFQAAHRLPVTGRHSAEIYATLLRQADAPARR"
     gene            complement(58244..59170)
                     /locus_tag="P5537_00710"
     CDS             complement(58244..59170)
                     /locus_tag="P5537_00710"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76592.1"
                     /translation="MNIDDDTLIAYLDAQLEDDAAYETVEDALAASPALRARLQVLAE
                     TGELARQAFDAKLEEAVPPQLIAAIMSAPLPGAEEGARTATPAADAGLARAPARPADA
                     AAAQPASGRPALTPSSAGSRPGATRPSTPGLGARLAAWLGGGFGAAAAFASVVTLALG
                     ALIGHYLLPPTELAAPLARVGDPIRDPALAMALQAAPSGVVLDAGGQRLEIRASFPAR
                     EGGFCREYTLGSTSGAGGGQQIGIACRTPAADANWQLAFSAGGEGDPNGYGTASDRLH
                     EAADAFLGENVDGAPLDAERERALITRGWNAD"
     gene            complement(59170..59679)
                     /locus_tag="P5537_00715"
     CDS             complement(59170..59679)
                     /locus_tag="P5537_00715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002934509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HRV76593.1"
                     /translation="MSATDPRAELVSLLPRLRRFAFGLTGDAHVADDLVQAGCLKAIE
                     RWHQWQPDTSLASWMFRILQTTWVDDYRSRQRQQTEADSDALEAIAGEDGRRVVEARS
                     DARMVRRVIGELPEEQRVVLMMITVDGLSYKETAAALGVPMGTVMSRLARARARLADA
                     IGGAPDGAR"
     gene            59944..61320
                     /locus_tag="P5537_00720"
     CDS             59944..61320
                     /locus_tag="P5537_00720"
                     /inference="COORDINATES: protein motif:HMM:NF012311.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HRV76594.1"
                     /translation="MNIPVSFLPARCCPASLRGSARALALLLALHAAAFAELPLWNGL
                     GFAGIGAHADDGDGGDGDGGGDGGGGGGAGGGDGGGGGGEAAADYEPLEDPLPIAGET
                     FIADELLLLSPTQAALNRATALGLRVIDRVQARQLGVSFARLRLPPGLDARSAREILS
                     ERGPGKFDLHHLYKIAQAAPAARCEGPGCAARELIGWPADSRACGRGQAIGIVDTAVD
                     AAHPALVGADLLRQAFVTDGKEAAPADHGTAVAALLVGQSDSVVPGLVPRARVFAAAP
                     FHTLPSGNATADTAGLVKSLDWLVGQGVAVIGMSLAGPDNAVLREAVRRVEARGIVVV
                     AAAGNGGRNAPPAYPAAHERVLGVTAVSADRRVYWRANQGDYIDYALPGVNVWTADPA
                     GGGRARSGTSYAVPYMVALASQTLAQRVASRDVLLDGRLGGLADLGDPGRDPVFGYGK
                     PRFDRDCR"
     gene            complement(61454..62185)
                     /locus_tag="P5537_00725"
     CDS             complement(61454..62185)
                     /locus_tag="P5537_00725"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76595.1"
                     /translation="MTCRTRTLTACAALAAGACAQLPAVPFHGDTLLDETRAALDTRP
                     QRIELSPAARPTLQRGDTFVFGRSTVTRVAATSAQTLTWTLPDGRSLHSPRDFFAPAL
                     SAEHPGYRVDSTIDGDPSALWPLAAGKRVSFGETRRTTWAETGHASEVRRRWDCEVVD
                     ARVSFVPAGDFATWHVRCSAFAPNFPLPLQTITWDYAPSLGHYVRRTWFADRRQREVM
                     LSAALPGKAATPARIEAVLARLASE"
     gene            62346..62846
                     /gene="tpx"
                     /locus_tag="P5537_00730"
     CDS             62346..62846
                     /gene="tpx"
                     /locus_tag="P5537_00730"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0016684 - oxidoreductase activity, acting
                     on peroxide as acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HRV76596.1"
                     /translation="MSKVTLGGNPIDIAGRVPQAGEAAPAFKLTGADLADVGLEAFAG
                     KRKVLNIVPSLDTPVCATSTRKFNAEAAGLADTVVLVVSADLPFAAKRFCETEGLQNV
                     HTLSTFRNPKFAQDYGVAITSGPLAGVTARAVVVVDGNDKVVYSQLVPEIKEEPDYAA
                     ALAALK"
     gene            complement(62889..64586)
                     /locus_tag="P5537_00735"
     CDS             complement(62889..64586)
                     /locus_tag="P5537_00735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FapA family protein"
                     /protein_id="HRV76597.1"
                     /translation="MDKQPTEGPELEASFDELTRTLSVSIAHDPRFPRIDALWLRRRL
                     EAAGYAELQIRPDPIRRLIAQYNAAESVEAVEIAQCVDASMQIGVSLDGLVARLSIVP
                     PKGGRPASKTELLALIESRGIVEGLLLDEINRAIASGQADELAIARGREPEPGKDGWL
                     EYLLPETRERVPSVRPCGRTDYRDLGEILVVHAGDALMRRHPPQPGVDGVNVYGRPIM
                     ARRGRDLRFAPGLRGTTTSPEDPELLVAACDGQPVRVRNGAMVEPIFTVDAVNLATGN
                     IDFDGSVRIRNDVQAGMTVRATGDIEVGGVVEPATLEAGGSIVVKGGVLGGLGGKTAG
                     KDYSTHALRCEGSFCATYAQQARISAGDSIFIDDVAMQCQLEARNHIRVGKRLRGQIV
                     GGHCRASLSIHARTIGANSRIRTELEIGMDTGLEYAIQEKAEARDALENRLLEIGKML
                     TFADRHPDRVTPEMVGRAEQTANALSGEIEILRGEEEDLQHRLALTREARVNADREMF
                     EGCIVRMGEQLFKLSQDRGPTTVRLATQGLGVFPLEDDSRFDEPQRPAAAGPNASRR"
     gene            complement(64687..66561)
                     /locus_tag="P5537_00740"
     CDS             complement(64687..66561)
                     /locus_tag="P5537_00740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018606307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HRV76598.1"
                     /translation="MTQLNTPYPSTAYLTGFLRSRGIDAVQEDLALKLVLRLLSPAGL
                     DDIRTRAEALPRKQRTPLVQGFLDHFTRYRYTIGPAIAFLQGRDPTIAHRIASRTFLP
                     EGPRFDTLDAYVDPDDPEGGDPLAWAFGAMGLADRARHLATLYLNELADILRDAVDAR
                     FEFVRYAESLSMSQPTFEPLAAALAAPPTLVDAYLKELTLEALSTHRPRLVLVSTPFP
                     GSVYGAFRIAQAIKAAHPEIVTVLGGGFVNTELRELAEPRVFDYFDYVTLDDGERPLL
                     ALLEHLQGRRGRSRLVRTFVRDPDTDQVRYIHLAEPDVPFAEVGTPTWNGLPLDGYLS
                     VLDMLNPMHRLWSDGRWNKLTVAHGCYWKKCTFCDISLDYIGRYDGAAASLLVDRIEA
                     IIAETGQTGFHFVDEAAPPKALRALAEELLRRGVAISWWGNIRFEKSFTPELCQLLAD
                     SGCIAVSGGLEVASDRLLQLMKKGVSVEQVARVTHAFTEAGVLVHAYLMYGFPTQTVH
                     DTVDALEYVRQLFEAGCIQSGFFHRFACTVHSPVGRNPEEFGVTLVPLPEIRFAKNDV
                     GFIDPTGVDHDRLGRALNKALYNYMHGIGLDTDVRTWFEDKVPRPRVAKHFIARALRA
                     "
     gene            complement(66705..68204)
                     /locus_tag="P5537_00745"
     CDS             complement(66705..68204)
                     /locus_tag="P5537_00745"
                     /EC_number="3.2.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008714 - AMP nucleosidase activity
                     [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0044209 - AMP salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AMP nucleosidase"
                     /protein_id="HRV76599.1"
                     /translation="MNGHAPYFEVEDFADPAAALARVHEIYDLAVDHLRRGLQHYVDG
                     ADVGRHVRACYPLLRVRTDTVVRADSRLSYGFVAGPGVFETTLTRPELFADYYLEQFR
                     LLVENHGVALQVGSSTQPIPVHFALPEHDYLEGHLGPERRRLLRDHFDLPDLGAMDDG
                     IANGTFEPGPGEPHPLSLFTAPRVDYSLHRLRHYTGTRPAHFQNFVLFTNYQFYIDEF
                     IRLGHELMADTASGHGYEAFVEPGNVVTRRSDLAPQAEDADGTPPPRLPQMPAYHLVR
                     GDHAGITMVNIGVGPANAKTITDHIAVLRPHAWIMLGHCAGLRNSQHLGDYVLAHGYV
                     REDHVLDEELPPWVPIPPLAEVQVALEAAVAEVTQLSGYELKRLMRTGTVASTDNRNW
                     ELLPSHGMSTSPERRFSQSRAVALDMESATIAANGFRFRVPYGTLLCVSDKPLHGEIK
                     LPGMADKFYRERVDQHLRIGIRALEQLRAQGVDRLHSRKLRSFAEVAFQ"
     gene            complement(68219..69010)
                     /locus_tag="P5537_00750"
     CDS             complement(68219..69010)
                     /locus_tag="P5537_00750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase-related protein"
                     /protein_id="HRV76600.1"
                     /translation="MNLPAVRDARLILEDRVATLTLARDDVRNALTGTALIDDIVGVA
                     EWANTCDEVSVLVITGEGAAFSAGGNVKDMAARGGDFAGDVAEVATRYRRGIQRIPLA
                     LQAVEVPIIAAVNGPAIGAGFDLANMADIRIASTRAKFGETFLNLGIIPGDGGAWFMQ
                     RLIGYQQAFELTLSGRIVGAEEAKTLGIVLEVVEPDQLLARAHELAARFAAQPPKALR
                     LTKRLMKMAQRMELKDFLDLCAAFQGMCHNEPEHLEAVQRMLARS"
     gene            complement(69080..69580)
                     /locus_tag="P5537_00755"
     CDS             complement(69080..69580)
                     /locus_tag="P5537_00755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LEA type 2 family protein"
                     /protein_id="HRV76601.1"
                     /translation="MSIPVRPSASSFTAALLALLVAVMLAGCASLIQREPVRINVVGL
                     EPLPGAGMEMRFAVKLRVQNPNEAAIDFDGLALELDLNGKPFATGVSDRKGSVPRFGE
                     ALVEIPVSVSAIAVVRQALGVIEGEPKTEVPYTLRGRLAGGLLGGTRFSDAGSLKLPE
                     PLRNPR"
     gene            69827..72430
                     /locus_tag="P5537_00760"
     CDS             69827..72430
                     /locus_tag="P5537_00760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HRV76602.1"
                     /translation="MLSAPPASSRVTSACYALVPATAATGAVLARYGELALVVVERVP
                     AVAWASWTDLDPIRVNGQPRILPSGHFDPGAGPRCILRFAGPVLPAWREMLAALGWTA
                     RFDCPPCGLCVEVGADLAALRTALPALRAIAPYEAEDCARAGAGGVAALPATVDAVAF
                     SEEDRARLEDELAAAGLRVVASSRYKLRVSGDGGAVGRLRDAVGVKIADPGTLARTAS
                     ASLRLAIGATETSVGDGGGPAAGAGGEGELIAFADTGLGSGATDAPHPDFAGRVQAIH
                     SWPLAPGWSAFVRAPGADDGGADRGSGHGTHVAGLAAGDGGMSAGRLAGVAPGARILM
                     QAIEQYVDPLPEWRGRLQPGFYLAGRPLDLRELLEQARAAGAAIHADAWGVEAAGAYT
                     DDSWECDHFLHAHPGMLVIVAAGNAGRDRNRDGAIDAGTLYAPASAKNVLAVGATEGP
                     DAGIGLRGGWAALDPEGTRFPDPVQRGAPVSGDAERLALLSSCGPTLDGRIKPDLCAP
                     GTNLAAARSAVSPSRGWGLANPLPWYQYLGGTSMSTGVVAGAAAVLRQRWRRALGEAP
                     GGAALKALLIHGARPVHRRDGQGEEDRERAGFGRLWLAGSLPGPDGPVLLEDRVGLAT
                     GTCRRIDCKGPGRLRAVLCWYDAPGEALINDLDLVLRDASGSVHAWGNHLAGAVGIAD
                     RRNTVECIDVQLGEGDWTLEVRGVNVPLGPQPWALAASPGVIVAGTPAAPGTSTAPAE
                     PLPAPRWRVDLPWTAVRGVGAKRAIELERTLPGGIGALCAGVPDAGTLAFLPAALRAH
                     IRSLAAFLGASPPSAAVLAVEHPTRALLAGPPEAASAADWQALAAALSPLLEALDRSV
                     AREVCGERLFR"
     gene            72452..73471
                     /locus_tag="P5537_00765"
     CDS             72452..73471
                     /locus_tag="P5537_00765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76603.1"
                     /translation="MADNTEKPGKGKPTRTQAGAMPASAALPEGSILSAGALIPGGGG
                     GVLANEADVSGELAELAPSFGDILASIGRGVADSQTALDRGLVDTATTLSQSTITVVT
                     DVVQELNDDGLPVPSATQLVTENVSLINFVRPTAHQWSHVALRMDMTVGAVDNERGIS
                     VNSKTKSARATNVGLFFGFLGIGVSSFKERSTFRSEESDFESNWAEGRVLMDALLQPR
                     NVEGFDPPAEVSIGPQIFMALGSVQETLNSGVVTARATDIVITVRKANGAVNPSVMID
                     VDPGPFDLSFATADGFTGNTTNAAGQCRITLSRNIPSPLFQRRVRGTVTATLGQIERS
                     TTVSL"
     gene            73499..74392
                     /locus_tag="P5537_00770"
     CDS             73499..74392
                     /locus_tag="P5537_00770"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76604.1"
                     /translation="MPDLLPSLPRVLAEDANVSDELRGAGIAFGTLVERTGAAVAATQ
                     LQLDTSSAATASALAATLVNVIAVREQVFRDDGTLDHVTNHVRPLPLISFIDPVFYQW
                     TSVRLQGEFYAREFAASSETTSAYSGSNFGLFGSGVSMFFGPGMLTSGSGSGSTTTTT
                     DVSTDVSLGRIRASALLEPRDDVGIPKPNQVIRGPRLALIQGEIADVMDGGDLIGRTM
                     SVLLQYSRRNGAPIAGKALSVESSGVPWRHLGTGVTDAAGQIQIELRRDFLDEDADTT
                     PASFVITARIGLVSNSVTVTF"
     gene            74444..74836
                     /locus_tag="P5537_00775"
     CDS             74444..74836
                     /locus_tag="P5537_00775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76605.1"
                     /translation="MDKANIGAGELAGQQAVELGELLARTVVSVAAAQEALDRHATDR
                     LDAIERGDEDAPRVPPLWYTFTEVTLEVALSASVERASGSVPPRLMSRPVDPRQVSLY
                     GYQASSSLMVRLRLAPRQGMPDVSPPPA"
     gene            74874..75836
                     /locus_tag="P5537_00780"
     CDS             74874..75836
                     /locus_tag="P5537_00780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4332 domain-containing protein"
                     /protein_id="HRV76606.1"
                     /translation="MPIDPKDLRSAAGSLLDPRLVDTMNLKPVGTSSLVSLEGKLGVF
                     TPVAEDGSGADNTEAVIAALRKELVRLESENAALRRQLAEVEAARKRSPDDFASAVAH
                     TLDTLQHKLAQTTNPVSRFAVREVAIDAQVTVDVSPLGTLEYRFVRPEDDIDPSKLSR
                     IRLDLVPLPREDAGLSAGPEFSPWAGVEDIVGVGETWRGALNRQQIFTIADLLVAGSR
                     LKSSAELAALVGVDRQRLAEWMGHAELLSVRTIDPRAADVLWTVGIRSLETLAGAATG
                     EVLEKYNAEVARRAHKSLAPIDAAQAAAWIEAAKKYHGRPREGG"
     gene            complement(75844..76557)
                     /locus_tag="P5537_00785"
     CDS             complement(75844..76557)
                     /locus_tag="P5537_00785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370583.1"
                     /note="Members of this family of hydrolases with an active
                     site Cys residue belong to MEROPS family C26; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HRV76607.1"
                     /translation="MKAHILQHVPFEGPGHIGDWLAARGADVGTSRLWESPALPDPAA
                     VELLVVMGGPMSVNDEAEFPWLIAEKRFIADVVARGRPVLGICLGAQLIASAHGARVY
                     RNTAKEIGWFEVAASGAEQGDEGEQGAAPRFPFPAHATVLHWHGETFDLPQGAHLLAS
                     SAACRNQAFQLGARTIGLQFHLEMTEPSLRAIVDNCRGELVPARWIQDEATILGRSGA
                     HFAATHALMDGLLDWLVRD"
     gene            complement(76593..77201)
                     /locus_tag="P5537_00790"
     CDS             complement(76593..77201)
                     /locus_tag="P5537_00790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF924 family protein"
                     /protein_id="HRV76608.1"
                     /translation="METPATIHAFWFGPAADEDEEDVIIERQSALWWKKQPEVDAAIR
                     ARFAPLVGRAAVGEFDAWLGGLRGRLALILLTDQFPRNIWRGEAAAFAFDVLALRWAK
                     DALARGLDGELRPIERVFLYLPLEHSENLADQREAVRRFDALAAAVEPMLRPAFAGYL
                     DYARRHLEIIERFGRFPHRNGALGRETSPEEAEFLRQPGSRF"
BASE COUNT        11369 a        26575 c        27520 g        11715 t
ORIGIN      
        1 gccgcgtcgc gcagcgcctc gtccagcgtg cacggcttgc ccagcacgct gaacaccgcg
       61 tcgatgccgt gcgcgtgcac caccccgacc tcggcgccga gcgagccggc gatgccgatc
      121 accggcttgc cgtggcgctt ggcgacgcgg gcgacgccga tcggcgtctt gccatgcacg
      181 gtctggaagt cgatgcggcc ctcgccggtg atcaccaggt cggcgtcgcg cacgtgcgtg
      241 tcgaggtcca ccgccgcagt gacgatctcg atgccgggct tgagcgtggc gccgaagaag
      301 gccagcatcg ccgcgcccat gccgccggcc gcacccgcgc ccggcaccgt gtcgaccgcc
      361 acgccgaggt cgcgcccgac gatgcgggcg aggcgggcga ggttggcgtc gagcacctgc
      421 accatctcgg gcgtggcgcc cttctgcggg ccgaacaccg ccgaggcccc acgcgcgccg
      481 gtgagcgggt tgtccacatc gcaggcgacc tcgatgcggc actccctcag gcggggatcg
      541 agcgcgcaga cgtcgatgcg atcgaggtcg gcgagcgcgc cgccgcccgg gccgagttcg
      601 cgcccctgcg cgtcgagcag gcgggcgccg agcgcctgca ccatgccgac gccgccgtcg
      661 ttggtggcgc tgccgccgat gccgaggatg aagcggcgcg cgccggcgtc gagcgcggca
      721 cggatcagct cgccggtgcc gcgcgaggtg gtcacgagcg gattgcgccg atccggcggc
      781 accagcgcca ggccgctggc ggccgccatc tcgatcaccg cggtcgcgcc gtcgccggtg
      841 aggccgtaga aggcctcgac cggttcgccg agcgggccgc gcacggcgac gacctctttg
      901 tgcccaccgg tggcggccac catggcgtcg accgtgccct cgccaccatc ggcgaccggc
      961 accagcacgt actcggcggc ggggaagacc tggcggaagc cggctgcaat cgcctgcgcg
     1021 acctcgagcg cggacaggct ctccttgtag gaatcggggg cgatgacgat ctttttcatt
     1081 agtggctcca gtcgctgcgg gtcgaatgcc cgctggagtg gagcttattc ccagtcggcc
     1141 gacaatcaat cgtctgttta aacaaaacca gcaccttgaa tacaggttat gttgtcaact
     1201 ccgactattc ttcaccagta tccagttcga ggccgatgaa caacagcagg cagtcgttca
     1261 gacgggagag gtccagcgcg gtgatctcgc cgatgcggcg cagacggtac tcgagggtgt
     1321 ttcgatgcac atggagcgca ccggcgctca gcgccgcctt catgtcgtgc gcgaaccacg
     1381 ccgccagcgt gcgccgcaac tggccgtcgc gatcatgccg cgcgaggcgg cgcaatggac
     1441 ggcgcagttc gtcggcccgc cagccctcgc ccaggccggc gagcagcacc ggcagggtga
     1501 gttcgtcgta gcagtggatc gccgcctgcg ggcgatggcg gcgcccggcc tgcagcgtgg
     1561 cgcgcgcgga cttccaggaa cgcacgaggc catcgtcgcc accgaaatac ccgccgaggg
     1621 caagacaggg ctggccgctg ccctcgccgc aaaggcgttc gtgcagggcc tggaggcggc
     1681 cccgcagatc ggatgccgcg gcaggcaagg gcatcagcac ggccagctca cgcagcgtga
     1741 ccggcgcaca ggccaggccg ggctcgtgct cggcgagcag ccggcgcagg cgctgctgcg
     1801 cggcgaggac ggcatcggcc gccagccccg cgtcggcgat ctcgatcagc aaggcgacac
     1861 acggtcgggc gagatcgacg ccgagacggc gcgcccagtc gtccagcccg gcgcccggcg
     1921 gggacacgcc gatccgctgc aggaccagtt cctcgcgcag gcgctggtcg cgcgcgagca
     1981 tctgcatcca ttgcgcctgc tccagcatgg tctctgccgc cagtcggacc agttcggcgt
     2041 gctggcggac agcatccggt tcgccgctca ggcccaccac gcccaccacc ctgccttccg
     2101 cacgcagagg caggttgata cccggtcggg tatcgtgcag gcgctgcgcg accgcctcat
     2161 cgatctccac cgcccgcccc tgcgccagca ccagcagcgc accctcgtgg cgggtcccga
     2221 ggcgcgcgcg atcgccgctg gcgatgacca gcccgcgctc gtccatcaca ttgacgttgg
     2281 tgcgcaggat ctgcatcgcg cgatcgacga tggactgggc gagcgaggca tcgagcagga
     2341 acatgacggt gcgccggtgg cggattggac gggaaccggc cacatgctgc cgcgcgccgt
     2401 gccgcggaac aagagcggca ccggcggcgt cggacatgta cggtccggaa tttcccgtca
     2461 gcccacccgt ggaggccgaa catgacccgc accgaaaccg acagcctcgg cgcgatcgaa
     2521 gtccccgccg aagcgtattg gggcgcacag acccagcgct cgctgctcca cttcgccatc
     2581 ggcgacgagc gcatgccgct cgccatcgtg catgcgctcg cgctgatcaa gaaggcggcg
     2641 gcgcgcgtgc atgcccgcag cggcgagctc cccgcggacc ttgccgagcg gatcgaacag
     2701 gcggccgacg agatcctcgc cggacgtcat gacgcgcagt ttccgctcgt ggtgtggcag
     2761 accggcagcg gcacgcagac caacatgaac gtcaacgagg tcatcgccgg gcgcgccaac
     2821 gagctcgccg gactgggccg cggcggcaag gcgccggtgc atcccaacga ccacgtcaat
     2881 cgcgcgcaga gctcgaacga ctgcttcccg accgcgatgc acatcgccgc cgcacgcgcg
     2941 gtgcacgacg agctgctgcc ggcgatcacc gagctgtcga acgggctggc gacccaggcc
     3001 gaacgccatg cggaggtgct caagaccgga cgcacccacc tgatggacgc cacgccgatc
     3061 accttcggcc aggagctgtc cgctttcgtc gcccagttga acacctctgc gcatgcgatc
     3121 cgcgcgacgc tgcccgcggt gtacgagctc gcccagggcg gcaccgccgt cggcaccggg
     3181 ctcaacgcgc cgccgggctt cgccgcggcg atcgccgacg aactggcggc gctgaccggg
     3241 ctgcccctgg tcggcgcggc gaacaggttt gccgcgctcg ccgggcacga gccgctggtt
     3301 gcgctgtcgg gcgcgttgaa gacgctcgcg gtcgcgctga tgaagctcgc caacgacctg
     3361 cgcctgctcg cctcgggccc gcgcgccggc ctcgccgagg tgaagctgcc ggccaacgag
     3421 ccgggcagct cgatcatgcc cggcaaggtc aacccgacgc agtgcgaggc cttgtcgatg
     3481 ctcgcctgcc aggtcctcgg caacgacgcc acgatcgcct tcgccgccag ccagggccac
     3541 ctccagctca atgtgttcaa gccggtgatc gcccacaacc tgctgcagtc catccgcctg
     3601 ctcgccgacg gttgccgcag cttccagcgc cactgcgtag ccggcctgga acccgacacc
     3661 acgcgcatgg ccgagcacct cgatcgcggc ctgatgctgg tcaccgcgct caacccgcac
     3721 atcggctacg acaaggcggc gcagatcgcg aagaaggcgt gggcggaagg caccacgctg
     3781 cgcgctgcgg cgctcgcgct cggcttcacg accgcggagg agttcgatgc ctgggtgcgg
     3841 gcggataaca tgctcggccg ctgaaagctg catccggatg tgatcgtgat tgcacgggga
     3901 gaaagcgcac gcgcgcccgg cagggctgcg gcgagtgcgc ccgatggtgg ttgtgcgcgg
     3961 gtccccaccc tctcgcggat gcgaaacaat tcgcaacgct gtgccgggat cccggcgtcg
     4021 atcccgcact catactgcgc acaccccgac agcgcggcgg catccccttt ccaccgcgca
     4081 ccgacaatca caaggaggcc ttcatgaaag cccgtaccct catccccgcc ctgctcatca
     4141 cctttgccgc aagcggctgc gccacctggg acaacctgtc ctcgcgcgag aagagcgcag
     4201 ccaccggcgc cgccgtgggc ggcgtggccg gcgccgtggt gagcaacggc ggcatcctcg
     4261 gcacggtggg tggtgccgcg atcggcggcg tcatcggcga ccaggtcggc aagaacaaat
     4321 aggcgccacc gtccctcggg atgccgcccg ccgttctccc cgcggcgcgg catccccctg
     4381 attgcttggt agaatcccgc tcgtcccgcc gcgcccgacc tcgggcgggc ggtttttgct
     4441 ttcctgccga cgagccccga tgaccaccac ccccttcccg cccgagctgc tgcgcgacgt
     4501 cgaaaagcgc cgcaccttcg ccatcatctc ccaccccgac gcgggcaaga ccacgctcac
     4561 cgagaagctg ctgctgttcg gcggcgccat ccagctcgcc ggcacggtga aggcgcgcaa
     4621 gtccgcccgc cacgccacct cggactggat ggaggtggag aagcagcgcg gcatctcggt
     4681 gaccagctcg gtgatgcaat tcgagtacca gggtcacacc atcaacctgc tcgacacccc
     4741 gggccacgag gacttctccg aagacaccta ccgcgtgctg accgcggtgg acgccgcggt
     4801 gatggtgatc gacgccgcca agggcgtgga ggcgcagacc atcaagctgc tcgaggtctg
     4861 ccgcctgcgc aacacgccga tcatcacctt cgtgaacaag ctcgaccgcg aggtgcgcga
     4921 gcccttcgag ctgctcgccg agatcgagga cgtgctcaag atcacctgcg cgccggtgac
     4981 ctggccgctg ggcatgggca aggccttccg cggcgtgtat cacctgctgc agcaacaggt
     5041 gctgaccttc acgcctggcg aagagcgccg cagcgacggc gagatcatca agggcctgga
     5101 caaccccgag ctcgacaagc gcttcccgat ggaggtcggc cagctgcgcg acgacgtcga
     5161 gctgatcgac ggcgcatcgc cgcccttcga cctcgacgac ttcctcgccg gcaagcagag
     5221 cccggtgttc ttcggctcgg gtatcaacaa cttcggcgtg caggagatcc tgcaatcgct
     5281 gatcgactgg gcaccgccgc cgcaagcgcg cgacggcggc agccgcatgg tgcagccggc
     5341 cgagcccgcc ttcaccggct tcgtgttcaa gatccaggcc aacatggacc cgaagcaccg
     5401 cgaccgcatc gccttcttcc gcatctgctc ggggcgctac agcgccggca tgaaggtgcg
     5461 ccacgtgcgc gccgggcgcg agatgaagct cgccaatgtg ctcacgttca tggccaatga
     5521 gcgcgtgatc atggaggacg gcgtcgccgg cgacatcgtc ggcatccaca accacggcca
     5581 gctgcagatc ggcgacaccc tgaccgaggg cgagaacctc ggtttcaagg gcattcccta
     5641 cttctcgccc gagatgttcc gcgccgcgcg cctgcgcgat ccgctcaagt cgaagcaatt
     5701 gcagaagggt ttgcaggagt tgggcgaaga aggcgccatc caggtcttcg agctcgaagg
     5761 cggccagatg ctgctcggcg cggtcggcgt gctgcagttc gagatcgtcg cccagcgcct
     5821 gaaggacgag tacaaggtcg atgcgatctt cgaaccggcc gacatccaca ccgcgcgctg
     5881 gctgaccttc cccgacgacg tcacccggcg caacttcgag cgcgagcagg cgctgcgcct
     5941 gggcaaggat atcgacggca acccggtcta tctggccacc agccgctaca acctcgaggt
     6001 gactgcggag aagtggccca aggtcacctt ccacgcaacg cgcgagcacg gggaagtgct
     6061 gggctgagcg gcatgcggcg cctcagccga cgaggcgcca gccgcaagcc tcgaactgcg
     6121 cgggctcgcg gcttgcgtcg ctcctgcaga accgcctatc agcttcgggt gggccgcggt
     6181 gccgccgggg cgctcaccgc ctccacccag taggtctgct tgtgcccgtg cgcctcgaag
     6241 gcgcgcgcgg ccgcctcggc ctcctcccgg cgtgcaaaca cccccaccac gaagcggttg
     6301 tcgttgtcgt cgagccgcca cagcgcccag cgggtgggtt ccgtatccga atcgccgcag
     6361 ttcttcaaac cctcacccgc cttcgacgat cccgctcgca ggcccgttgc cggcgcgatc
     6421 gcagcgccat cagccgtgga cgaaccggcg cgcgaaggcc tcgacctctg cccagtcggt
     6481 gaagtcggtg accgagcgcg ggtcggtggg gccaccggtg atccacatga tcaggcggat
     6541 catgttgcgg tcgaagaagc cgtagcgcgg gtactcgatc ttgccgccga agatcgcgat
     6601 ctgctgcggc ttccagcgga tctgggcaag gaacttgcgc acgtaggggt tggtgtcggc
     6661 ctggcgcttg tgcggcttgc ggccgaccgc attgaccgag aagaaggcgt tgggccgcgc
     6721 ctcgagcgcc gcctggtggc ggtcgatgaa ggccttcact gcggggcggt ggtggccata
     6781 gcggatgctg gcgccgatca cgacgcggtc gcaggcttcg agctcggcag cggaaaccgc
     6841 agcgacctcg gccagttccg cctcgtgacc ggcgtcgcgc acgatcgctg cgatgcgctc
     6901 gcagatctcg agcgtgtggc cgtcgatggt cgaatagatg atcagcagac gcattgcctg
     6961 tcctggatgg acatatccgg agcgcaaggg gcgctcgagc gctcccgacc aaccggtgtt
     7021 tgccaacgtg aatggcgggt ctgccgaggc gtcccgccat ccccgacgcc caccttactt
     7081 gccggtgacg atgccctcga ccaccttctt gccctcggag tacagcgcca cctggccgtc
     7141 ctcgagctcg aggttcatgc agccggtgtt gcccttgagc ttgccgtcca gccactcgcg
     7201 gcagtagcgc gcctgatcgt cgacccacca gcgcgccttg gcgccagtgg tgtcggtgag
     7261 cgtgccgtcg gtgccgaact ggagcgtgta ggccgcttcg gtgcgcagat acacgccgat
     7321 gaaggtggcg cccgtcagca gcttctcgac ctcggccttg tccttcatga agttctgcgc
     7381 cagcgcggca ccggaggcgg tggcgagcgc gacggcggcg agcagggcgc ggacggtgtg
     7441 cgagggtttc agcatcgttg tcttcctttt agtggttacg tatccgggaa aatcgatcga
     7501 agaggcctgg agggcggtcc ggatggggcg tgctcagccg cgtgccccca ggcggccgac
     7561 gaggccgcgc agggtctcct ggaggtcggc gggcatcacc acgatcttgg cgctgcccga
     7621 ctcgccgagc ttctcgagcg caccgatgta cttctcgccg agcaggtaca tcatcggccc
     7681 ggcctggtcg ccgatgccgg cggtcacgcg gcggatcgac tcggccgagg cctcggccag
     7741 catcacctgg gcgttggcgt cgcgcttggc ggattccagc cgtgcctcgg cctcgaggat
     7801 ggcggcctgc ttggcgccct cggccttggt caccgcggcc ttgcgctcgc gctcggcggc
     7861 ggcctgcatc tccatcgcgc gctgcatgga ttcggacggc ttgatgtcct ggatctcgac
     7921 cgacttcacc gtcaggcccc agtccaccgc ctcgtcggcg atgctctcgc gcagccgcgc
     7981 cttgatcttg tcgcgcgagg acagggcctc gtcgagctcc atctcgccga cgatcgagcg
     8041 cagcgtggtc atgatcaggt tgcggatcgc ctcggagaag tcggtcacgc catacaccgc
     8101 cttgaccggg tcggtgacct tcacgaaggc gatcgcgttg gtcaggatca ccgcgttgtc
     8161 gcgggtgatg acctcctgct cctgcacgtc gaggatgatg tccttggtca ccagcttgta
     8221 ggcgacgcgg tcgaggtagg ggatcaggat gttgagcccc gggcgcagcg tggcgtgata
     8281 cttgcccagg cgctcgacca cccactcctc gccctgcgcg accagtcgca cgcccttggc
     8341 gatcgtgatc accacgaaca ccagcaccgc gatcgcgatc gcgagtcctt ccgacatgat
     8401 catctgcttg ccttcatttt ccagggattc ggatcaggcc ttcgtcacct tgacgtagct
     8461 gccttccacg ctcaccacct tcacgcgctc gccggcggcg atcgcggtct cggccacgca
     8521 ggcccattcg tccgcgccca gcaccggacg ctggaagcgc accttgccgc gctcgaaggg
     8581 ggcaaccgcg ctcaccagca gcccgacctc gccgatgacc tcgccggcgg cggtgccgat
     8641 cagggtcttc actcgcgaac ggcgggcgaa gctgaaccac agcacggtca tcgccatcga
     8701 cgcgatgatc caggccgcga tctgccgcga caacaccagg tcgggcaccg cgagcagcac
     8761 gaagccggtg agcatcgcgc cgagcccgaa ccagatgatg aagaaggagg gcagggcgag
     8821 ctcgagcagc accagcgcga tgccggcgat ctcccagtgc caccattcga ggaacagcgt
     8881 gtcgttcatg ggcagacttt agcgcagctc gccggggagc gggttcgcaa gcgctgatcg
     8941 cttcctgtgc aaggtttatc gggcggtggg aaagctgtga ccgcaggggg caggagattg
     9001 tggataagtc gcgaatgcag cgacgggtgt tttttcatcc acaaaccatc cctgcctgaa
     9061 acggcgctcg tgcaccgggt tttgctggat gtaaggcgat gatttttcgt tggaaaagat
     9121 gcttgtccac agatttggcg cgtacatgat ctttatgatc ttttaaatct ttaaattctg
     9181 tgtacaccaa gaagcgaacc cctgcaggcc tccccgcaat cggtgtggcc ccctgtagga
     9241 gcgccggcag gcgcgaagac ggcgtccgag caatcaccga cgctcatcgc tgctgcactg
     9301 ccctattcgc gcctgccggc gctcctacag gggcttacgg agccgtggtc ctcatgtagg
     9361 agcgccggca ggcgcgaagg cggcctctga gcgatcaccg acgctcatcg ctgctgcacc
     9421 gccctattcg cggctgccgc cgctcctaca ggggcttacg gagccgtggt cctcacgtag
     9481 gagcgccggc aggcgcgaag acggcgtccg agcaatcacc gacgctcatc gctgctgcac
     9541 tgccctattc gcggctgccg ccgctcctac aggggtttac ggagccgtgg tcctcctgta
     9601 ggagcggcgg caggcgcgaa gacggcctgg cacgttcaga acggcgggtc gtccgcggtg
     9661 acggcctgcg cgacccgctt gtccgcctgc aggcgcggca gctcggcgct gacggcgttg
     9721 gtctgcgccg gtgtgcccgc cagctcgcca cccagcgcgg ccacgaccgc cggcagcagg
     9781 tgggcgagtt cgccggtcat cagcgcgaat tcggcattga acagcgcctc ggcgtcgtcc
     9841 ttgtcggctt cgcccacctg gtcgcgcacg atgtcgagga agtcgaggcg cttgatctcc
     9901 agcttctcgg tcagtacgaa gctgatgcgg tcgtcgaagg tcagcgccag gcgggtcggc
     9961 agcttgccgg cctccaggtg gcccttgacg tcatcgcctt cgagcgggtg gcgtgcataa
    10021 cgcaccgcgg ccttgtcctc ggccaccgag cgcagctcgc agtcctggtc gatggtgaag
    10081 ccgtcgggcg cctcgccacc ggccagccag tcggccatcg ccgacatcgg cgacagctcg
    10141 gtgcgcagca gggtcagcgg gaagctgtcg agcgtgtggc gcagctgctc gagcatgtcc
    10201 tcggccttgc tctggctggc cgcatccacc accagccagc cgttgaccgg gtcgatccag
    10261 gcgaacatgc ggcggcggcg ggtgaaggcg cgcggcatca gctcctgcgt cacttgctcg
    10321 cgcagttcct tcaactgctt gcggccaagc ttgaagccct gctgctcggc cagctcctcg
    10381 gcgcgctcgt cggcctcctg cttgaccacc gcagagggca gcaggcgatg ctcgaagccc
    10441 aggcacacca gccactggcc gccgaccgca tgcgccagca cctcgttgcc cagcggcgac
    10501 agccagccgc ggctctccat gtcctggctg ccgcaggggt ggaagggctt cttcgcgagc
    10561 tgctcctcga ggcgctcgac gctcatgtcc cagttggcgg gaaggcgata gacctgcaga
    10621 ttcttgaacc acatgacggg gatctttcct gttgttgaga ttggagacga gggggtgccc
    10681 gggaccgaag aatgcgcgca aacgcgcgca ttggctgcga atgcagcacg accgtcccgg
    10741 atattcgcgg gtgagcctgc tctcgcggca gctgcgtgga agtcgccgcg tgccgtggaa
    10801 tcgtgggatg actactgctg gagcccgccg gactcggcga tcatgcggat gatgcgcacg
    10861 gtgtcgaggt cggactgatg gtaggccgag cgcacgaact cggcgtaacg cgcatcctcg
    10921 ccctggtcgg gtagcgaggt gtggtaggcg aaacggagga agagcgcgcc gggctcgggc
    10981 tcctcgatgg tgatggtcag gctgccgccg gcatgctgcg cgttggcttc cgactcgaag
    11041 cggatccagc gcagggtgtc gaagctcacc cggtcgcgga tcaccgcatg gccgaagtgc
    11101 aggtcgcgca ccaggccggc ctcgccgcgc tcgacgacgt ggcaggcctc gaggccgggc
    11161 aggaaggcgc gcgcatcttc cgcgcggcac agcaggccga accagagctc ttcgcgggtg
    11221 agcggggtca gcagcgggtt ggcgagatca ttgacctcga tcaggtgttc gaatttcaag
    11281 tgcatctcct gagcgggcag ggtggcagtt taccccgctc gaccggtagc cggcacgtcg
    11341 cgaaacaggg agatcccgca caactgggcg tcgcaccggt cttggcggag gatccgccct
    11401 gctaccatgc gcaccatgca actcgaacgc ctcctccatg cccagggctt cggcagccgc
    11461 aaggaatgcc gcgccctcat ccgtgccggc tacgtcagca tcgccggcga ggtctgcgac
    11521 gaccccaatg ccgacttcga ccccggtagc cgcgatggtt cgcccggact cgaattcacg
    11581 gtcgatgacc agccctggcg tttccgcgcc caggcctacg tggtcctgca caagcccgcg
    11641 ggctacgagt gctcgcagaa gccgaccttt cacccctccg tctttacctt gctgccgccg
    11701 cagctgctcg cccgcggcgt gcagtgcgtg ggccggctcg accaggacac caccggcctg
    11761 ttgctgctct ccgacgacgg ccagttcatc caccagtgga gctcgggcaa gaagcgcacg
    11821 cccaaggtct atgagatcgt gctcaagcat gcggtggagc aggatttcgc cgatcggctg
    11881 gtggccgggg tcgagctgca cgacgaaccc gcaccgatcg cggcggcggc ctgcgagctc
    11941 gtcggcccga ccacgctgcg gctgaccatc tgcgagggca agtaccacca ggtcaagcgc
    12001 atggtcggtg cggcggggaa tcgggtcgag gcgctgcacc gcagccgcgt gggcgggctc
    12061 gagctgccga ccgggctggc accgggacag tggcgctggc tggaggcgga agacctggcc
    12121 cgcctcgccg actacgccga cccggaagcc tgaactcccc cggacagcac gcgaagggtc
    12181 agatgcagga gttgcccgca ggcaggaatg caaatgtggg ctttctcgtc cccatcggtg
    12241 gtcgaaccgc cttgttcgcg gctgccgccg ctcctacaga aaaacgtcgc gggcgggttg
    12301 cagtagcgcc tgccggcacg aaagcgtccg tcgaggcggg cgcgccgatc gattgtccgc
    12361 cccgtgcgtg gcttagaaac gcatctccag attcacgccc gccgcccaag cgcgctcgcg
    12421 ttcgcggtcc tcgcgctgcg gccagtagtg accgacgatg aactcgccga tcagccactc
    12481 gcgatagacg ggctgcgtcc atttcatccg cacgccgtat tcgtcgacgt tctcttcggc
    12541 accggtttct ccggtcacca ccatctcacc cgacaggatg cggtcatcac cgaagcgctt
    12601 gaacaggccc aggctgctgc cccaggcgaa gtcgtcggtc ttctccgaga tcgtcgtcgc
    12661 gttctgccaa tgcagcgata gcgtgggggt gaaggcgtgc tcgtagtcga gcgcggtcgt
    12721 cgagccgaac ttgtccttgt tgttccagaa gatcgtctcg cggaattcga tgcgatcctg
    12781 ctcggtcagc gcccactgct tgcgatagcg cgcctgcgtg tagaacttca tgccgccgcg
    12841 cacaccgaca cggaagtcga gattcttgcg caaggccagg cccacgccgg cgaagccggt
    12901 ctggtcttcc ttgcggcgct cctcgagcag gagctgctcg cgggtgaaag cctccgcttg
    12961 gtcggtgacg agttcgcgtt cgttctgccg gccgatgaag acgtaggcct tgtcgcgcag
    13021 gttgggcaga tcgaagcgtg cgcgaaagcg cacgttggta tcccagccct cgtcctgccg
    13081 ccataggttg cgcaggccaa gacgcccatg ggtgaccttg ccgccctcct cgaagggccg
    13141 atcgccgaac cagtcattca cggtctcccc caaccagaag gagaaacccc gtacctgggt
    13201 gcggctctgt tcgagcaggt cctgttcctg cgcggcctgc ggggaaaccg ggttggcggc
    13261 gggttgagcg atcgcgagcg aaggcaaggc cagtagcagc gcgatggaaa gcagcgatcg
    13321 aacgggcatt gggaaggatc ctgatgcgtg ggcctgaagg cctcttcggt ggtttatggt
    13381 cggagccatg gccacatcat gccggcagta tcgtgcgatg ggcaagctca ctgggctgag
    13441 ccgtgggggc caggtttgtt cttctgtttt tctattgatt taaataacaa agaagttaac
    13501 agtggcgcgt ttcttgtgga taagtctcca aagctcatgt ctatcgcgac ttccatcggt
    13561 ttgaaaagcg gttgagaagc gccctggtcg cctgtgtgcg cattgttgag ccttttgcgt
    13621 ccggtcgtct gaaaggcgct tgttcacaag ccatccccat tctttgcgca ggattgtccc
    13681 catcatgcat tcctcctcgt cggccgcccg ccccagatgg gagctcttct gccaggttgt
    13741 ggataatttt ggggatattg gcgtgtgctg gcggctggcg gcagatctgg cacgtcgcgg
    13801 ctgtggctcg gtgcggctct gggtcgatga ctgggaggcg ctgcgccgca tctgtccggc
    13861 tgcgaacgcg gtggacgagc gggtcggcgg gagcgtggag ggcgtggaac tgcggcgctg
    13921 gacgaccgcc ttcgtgccgc tcgtgccggg cgagatcgtc gtcgaggcct tcgcctgcga
    13981 gctgccgccc gcccagctcg aggccatggc ggcgctgcag ccggcgccgg tgtggatcaa
    14041 cctcgagtac ctttcggccg aggcctgggt cgcgggttgc cacggcctgg cttcgccgca
    14101 tccgcgcctg ccgctggtaa agcatttctt ctttcccggc ttcgatgccg ggagcggagg
    14161 actgttgcgc gaggccgacc tgctcgcgcg ccgcgatcgc tggtgcagcc agccggaagg
    14221 cgccgccggc tggttcgccg cgcgcggcat caagagcagc cgggatgcgc tgcgggtgtc
    14281 gctgttcgcc tacgagcagc cggacctccc cgcgctgttc gaggcctggg ccgatggaga
    14341 ccgtgaagtg ctcgtcctgg tgccggagtc gcgtgtgctc ggtgatgtcc gtcgcgcgct
    14401 cggccgcgaa tgcctgcagg tgggtgatcg ggtggagcgt ggcgcgctcg tgacctgtgt
    14461 gctgcccttc accgaccagg caggctacga cgtgctgctg tgggcctgcg agctcaattt
    14521 cgtgcgcggc gaggattcct tcgtgcgcgc gcagtgggcg gcgcggccct tcgtctggca
    14581 gatctatcca caggccgatg cggcccacca cgacaagctc gaggccttcc tcgcacgcta
    14641 cctgcagggg ctgccggcgg ccgaggcgga tgcgctcgcg cggttctggc gcgcctggaa
    14701 cggctacgct tccgatcgat cgagcctggc cgaggcctgg cccgccttcg ccgcggccgt
    14761 gccggccctc gaacttcacg cgcggcgctg gtgcgacgcc caggcggccc tgcccgatct
    14821 cgcgaccgcg ctcgatgcat tctgttccca catcgagcac gccgcgcggt agaatcgcgc
    14881 gctaattttt tcaaggacat gcgaccacga gtcgcgtcga accattcagg aaacagcatg
    14941 aaaaccgctc aggaactccg ctccggcaac gtcgtgatgg tcggcagcga cccgctcgtg
    15001 gtgcagaagg ccgaatacaa caagtccggc cgcaacgccg cggtcgtgaa gatgaagttc
    15061 aagaacctgc tcaccggcgc gccgtcggag tcggtctaca aggccgacga caagttcgag
    15121 gtcgtcgtcc tagaccacaa ggaagtcacc tactcctact tcgccgaccc gatgtacgtg
    15181 ttcatggacg ccgactacga gcagtacgaa gtcgaagcgg acaacatgac cgatgcgctc
    15241 aagtacctcg aggatggcct gcagtgcgag gtggtgttct acaacggcaa ggcgatctcg
    15301 gtcgagctgc ccaacagcgt ggtgcgcgag gtcgtctaca ccgagcccgc cgtcaagggc
    15361 gacacctcgg gcaaggtcat gaagccggcc aagatcagca ccggcttcga gctgccggtg
    15421 cccgccttcg tcgagatcgg cgacaagatc gagatcgaca cccgcaccga cgagtacaag
    15481 aaccgcgtga agtaagccgt tctgtcgtga tgaaaacaat ggggcccgtt cgggccccat
    15541 tgtttttccg cttgttgcag cgtgcatttt gcggttcttc ttcgcgccgg gattgcgtaa
    15601 cctgcatcct gtcgtcgtcg aagtcgccct cgtccctcat gaacgcgtcc cgcctgctcc
    15661 tcgccctcgc cgcctccctc ctcgccactg cctgcgcacc cgaacccgag acgcagccca
    15721 aggccgaacc ggccgttcct tcccccgagg cgccgcgcag cgaggccgcc gaggctaggc
    15781 gcgaagcggc cgaggccgct cgcgaggcag tgcagaaggc tggtgaggcc gcgcgcaaga
    15841 tcggtgaggc ggggagcgcc gcggtggagg cggcagtgcg caccgccgcc gagaaggccg
    15901 ccagcgagct cgccaaggat tcgtccgatg attcggtcgc gggggggctg catcaggcgc
    15961 ccaacgagga tcgtggtggc gatggccgcc cggccgagac cgtgcgcgac gccaggcaag
    16021 ccgccgagca ggcggcgcac cgcatcgccg aggccacccg cgacgcggcg gagcgcctgc
    16081 gcgaggtcgg caagggcgcg ctcgagagca tgcgtgcgcg taccgagctg ccgacgcagg
    16141 aggccgcgcc ggtcgaggag cgcagcgcag taccgatcga ggacggcaag gagccggccg
    16201 gccggtaatc ggcgtggtgc aggcgaaggg cgtatccatg gcgagcgcat ccgtcttccg
    16261 taccctgctg ctgctcgcct gcctgctgtt cacccaggcg agcccggccg ccgacgccgc
    16321 catggccgcg ccggcgctcg atctgcccgc cccgggccag cttcacgtct acgtgcgtga
    16381 aggctgcccg cactgtgcgg aggccaagcg cttcctcgcc agcctcgccg gatcccgccc
    16441 cgggttgcag gtcgtgctgc gcgaggtcga tcgcgatccc gccgcgcgtg atgccctggt
    16501 ggcgatcagc gaggcggtcg gggcgtggcc gccgggcgtg cccaccttcg tctacggcgg
    16561 tcgcgttctg gtcggcttcg acgacgccga gcatgtcggc gccgagctgc tgcgcctgct
    16621 cgacgaggct ccgccgccgc cgcgtgaccg ggtggaatcg agcctgttcg gcaccttgag
    16681 cgcgagcgag ctcggcctgc cgctgtttac cctggcgctc ggcctgctcg acggcttcaa
    16741 tccctgcgcg atgtgggtgc tgctgttcct gctctcgctg ctggtgcggc tgcaggaccg
    16801 gcgccgcatg gcgatggtcg ccggcacctt cgtactcgcc agcggcgcgg tctattacgc
    16861 cttcatggcg gcctggctca acgtcttcct gctcgtcggc atgaccgccg cgctgcgcgt
    16921 cggactcgcc gtgctggcga tgctgatcgg gctgatcaac gtgaaggact tcttcgcctt
    16981 ccgccgcggc gtctcgctgt ccatcccggc gtcggccaag ccgggcatct acgcgcgcgc
    17041 ccgcgccatc ctgaaggccg aatccctgcc cgcctcgctg gtcgcggtcg cggcgctggc
    17101 agtggtggtg aacttcgtcg agctgctatg caccgccggc ctgccggcga tctacaccgc
    17161 ggtgctcacc agccagggcc tttccccgct cgcccactac ggctacctcg gcctctacat
    17221 cctcgcctac atcgccgacg acgccctgat ggtcggcacc gcggtgctcg cgctcggcag
    17281 cggcaagctt accgagagcg gaggccgcct gctcaagctg ctctcgggcg tagtgatgct
    17341 ggcgctgggc gtggtgatgc tgctgcggcc gcagtggctg atgtaggcgg gtgcttcagt
    17401 ccgtgccgcg gcgccacacc gcggccagcg ccgcgagctt gttccacgcc gacaggcgtt
    17461 cgtcggatac cgcgtcgagg aagtccgaca ggcgcttcga cttcaccatg gtgtacatgg
    17521 tcagcccggt ggacaccgcg aacaccagcg cgaaatagag caggcgctcg ctcagcggcg
    17581 actcggcctc tgcgagcagg ttcatgccga ggaagccggt ggtgatggtg ccgatgaggc
    17641 cgaagatcgt gaccacggtc agccgcacca cggtgttggc ctggcggcgc aggctgtcgg
    17701 cctcgaggta gccgttcatg tccgcggtgc gctccttgac ctcggcatag agcgcgtcgg
    17761 tgcccaggtg cgcggtactc atgcggaaca gcgcgcgcgt ctgcgcctgc tcggcgatgt
    17821 cgtggaacca gtagcggtgg gtgaagcgca ggaagccctc gaagctggcg cggatcgcgc
    17881 gcttgaagcg gcgcacgctc gccggatcgg cgacatgcag gcgcttgagc gcctcgacca
    17941 ggcgctccga gaacatcagc agcgccgcct tctggaagtg cgcgatcagg aagagcagga
    18001 agtgctggtg gcggaactgc gccagcacgc cgcgctcgcg gtcggtgaaa taggccgatc
    18061 ttgcatcgcc caccacgacc agcgcgtggc cgctgcacag gtagcgggtc cagggcgccg
    18121 cgccgctcgc ggaccagaag cggtcgtagc agtagcggcg ctcgaagtcg tccagatgcg
    18181 ggttgccgta gggcagggtg ttgccagcgc cttcccgctc ggcgtcgcgc ggccccgcgc
    18241 cggtcaccag gccgaggcgg acgaagtcct gccgtgtaag cgccagcggg tcgtcgagcg
    18301 cgagataggc cgtcagcggc atgcggtgat actcgatctg acggtagcgc agcgcgcccg
    18361 gctgctcgga gtaggcgctc gcaagcggct gcatcagcca ggcccagtgc gacgcgatgc
    18421 gcggcgcgcg gtggcggctc acatgcgcca tgaacgcctc gcgctcgtgc gcatcggtgc
    18481 gcgccagcac cgacccgtcg cgcccgagca gttcggcgac ggcgaggctg tgcagcgcgc
    18541 ggccatgctc gtcccagccc gaagggtagg cgcggccgat gcggtacatc agctcctgca
    18601 cctcggacag gggcaggtcg cccccggcca cctcgacgtt gaggatcacc acatcgatgt
    18661 cgaagaaaaa atacagatgc acatggacga catcgagcgt caccggcgtg tcgccctcgc
    18721 gggcggcgac gcgcagcctg gcgatgtcgc ggcggcggaa cacccgcatc gccggcccgg
    18781 catccgccga gtcgctgtgc tgcgcgcgcc cctcgccgta caggagctgc tgcacgtaag
    18841 gcaggaaggt gacgaactcg ttgtagtggc gttcctggaa gacgctgccc tcgacctcca
    18901 ggtcgtgctc gacctcgcgc cacggcgacg cctcgcccag gtcgcgcagc acctgccacg
    18961 ggcgctgctg cggccccagc acacccgccc ccgtcagcag ccgcagcggc cacagcaggg
    19021 cgaggcggaa atgcttcacc gtcagctcgg cagcgggctc ggccatgacg tgtctccctt
    19081 cgcttcgcgg gttcttgtcc gggcagtgta gcgacaggag agggcaggcg ggcggcgagc
    19141 gtgctagggg gcggtccccg gcaggtcggt cgtcgcatcc gccacgcccg ccgaggtttc
    19201 gagccacttc cgcttctccg tcaccttggc ccacgtgttc gcgtcgggca gcgccggatg
    19261 ggcctcgacg atgcgtcgcc aggccttcgc cagcgtggcg ttgagcgcga ggtattcgcg
    19321 ctgcgccgcg gtgagctcat cctccgggac gatcgcatcc accggacatt cggccacgca
    19381 cagggtgcag tcgatgcact cctccggatc gatcaccagg aagttcgggc cctcgcggaa
    19441 ggcatcgacg gggcacatgc tgacgcagtc cgtgtatttg caacggatgc aggcttcggt
    19501 gacgacgtgg gtcatggccg cgcctcctcg aacagggtct ccagcacggg aaagagctcg
    19561 cgctcctcga agcgcacatg gtcgatcagc gcctgcccgg cctgcgcctc gtcgcggccc
    19621 cgcagcgccg cggcgaacag cagcctgagc tgcgcgtgct ccgcgcgcag gcgttcggcg
    19681 agcgccaggt ggcgatcggt gtcgagcagc ggcagcaggt cgcgctcctc ctcggcgaaa
    19741 tgggcttcga ggcccggcag ctccgcgtcg agctcggcct gcgccccgcc cgcgagcaga
    19801 tgcctgccga ggcgcagcgc ggtgtgatgc tcacgggaca actgggcgag acggctgtgg
    19861 cgtttcatgg cggatccttg cggcaactcc ttgaagagga gtatcaaact cctcttttaa
    19921 agagtcaact catatgaatc tattgttgct agcatggcgg ctacagccac gcctctgcac
    19981 gccctgccga tgaacatcac ccagcacacc gactacgccc tccgggtact catgtacctg
    20041 ggggcggtcc ccgagcggcg cgtcaccatc aaggaggtgg ccgaacgctt cgacatctcg
    20101 cgcagccacc tgatgaagat cgtcaccgag ctggtggcga aaggcttcgt cgacggcgcg
    20161 cgcggcaagg gcggcggctt gaggctggca cgcgcggcga gcgagatcgg cctcggcgac
    20221 gtggtgcgcc agctcgaacc cagcctcgcg ctcgtcgagt gcttcggaac gcagtcgcac
    20281 tgcgtgctgg atccggcctg ccggctcaaa ggtgcgctgg acagcgccct gcaggccttc
    20341 ctggccgcgc tcgaccgcgt ttcgcttgcc gacctcgtcg gcagcgacgc acggctgcac
    20401 gcggcgctcg gcctgcaagc ggcggcgcgc gccaccgtgc caatcacgat cgtgcacccg
    20461 cccgccggtc gcgagcggcg atagtcgggg cgcgctgcac catcggatga cggtcggcct
    20521 gcggttcgtt ggcgcgcaga gccgcgggcg ggttcttcgc gcgctgctcg caacgcattc
    20581 gccgcaggga ggctgggcca tgctaattta tgtcatgttg tgatataaat tcctcgaccc
    20641 gcccaaacac gccagcagag atcgatcatg tcctccctcc atctgccgcc catgctgtgg
    20701 tcctcggacg ccgcctggac cgagctctcc cgccgtccgc cctcgctggc caccctggtc
    20761 ttcggggtcg ccctgccggc cgccatgttg ccccccacga tgttgtcgca tgcgaccgac
    20821 gtcggatcgg cccactatct gcccgccctc tccgcttccg cctggcagtt tgtggagttc
    20881 gcgctgttcg cagcgcaagt cgccggcttc ctgatgatcc gctggctgat cggcgccgtc
    20941 gcggcgagcc atggggtgcg ggcgagcgca cgcgacgcct gtctgctcgc gacggtatcc
    21001 ctgctcccgc tctggctatc gtcgttcgca ctcctgcagg acgggacgct cgccgtcctg
    21061 gtgctgccgt tgctggcgat cggtgcctcg gtcgcgctgc tgaagcgggg tgtccgctgc
    21121 atgctcgggg ttcgtgagga gatcgtggcc ctggagatcg gcatcgtcgc gatccactgc
    21181 ggcgtgctgg cctgggctgc aacgatggcg gtgttccttg tcccgggcct cccggcgctt
    21241 tgacgtggac agaacgcggt ccggcccgtg gggcggatgg cgcgctcccg ccctgcctct
    21301 tcaggacgaa cgccgcagca gcgccaggcg gatgcgttcg atcgcgtggg aagggctcag
    21361 gcccttcggg cagacctcgg tgcagttcat gatcgtgcgg cagcggtaga ggcgatagac
    21421 gtcgtcgagg aagtcgaggc gctcggcggt ggcggtgtcg cggctgtcgg cgatgaagcg
    21481 gtaggcctgc agcaggccgg aaggcccgat gaacttgtcc ggattccacc agtaggacgg
    21541 gcagaacgca ctgcagcagg cgcacaggat gcactcgtac agcccatcca ggcgttcgcg
    21601 ctcggccggg gtctgcagcc gctcgcgctc gggcaggggc tcgtcgttga tcagccaggg
    21661 gcggatcgag tggtagtggg cgaagaactg cgtcatgtcc acgatcaggt cgcggatcac
    21721 cggaaagcct ggcagtggcc gcagcacgat cggctccttc agcccgtcga gcgcggtcag
    21781 gcaggcgagg ccgttgcggc cgttgatgtt catcgcgtcc gagccgcaca cgccctcgcg
    21841 gcacgagcgc cgaaacgaca ggctgtcgtc ctgcacgcgc agccgcatca gcaggtcgag
    21901 cagcttcttg tcgcccgcct cgggctgcac ctcgtaggcc tgcatgcgcg gtggcgcgcc
    21961 gcgctccggg tcgaagcgat agatgttcag tctcatgtcg cgcccttccc cgctcaggtg
    22021 gacaatgccg ccgcggccag gctcagcagc acgcgcacca gcacgccgag cagcacgacc
    22081 gcgatcaggc tcagcaccgc cagccgcaag ccgcgcggct ggatatagtc gagcacgatg
    22141 tcgcgcaggc cgacccaggc gtgcgcgcac aaggcgccga acagcagggc gatcagcggc
    22201 ccaccgagca cgccgcccgc gaaggcgcgc cacgcggaga aatcgagcgg tgacgcaaag
    22261 ggcagcgcga gaacggcgag cacgagcagc agcaaggcgc tgatgcgctg gaccacccag
    22321 gcccgctgtc cgtcgaacag cctcatgaca acccccagaa gagcaggaac actgccagcg
    22381 ctggcgcggc gatcaggacg aggcgggcgc tggcgcgcgc acgctcgagc tcgccgccga
    22441 tgccgacgtc catcagcagg tggcggatgc cggccagcac gtgatgcacg agcgcccaca
    22501 ccagcacgcc ggctgccacg accgcaagtg gcgacgaaat caaatcgcgc accgaggcga
    22561 aacccgcctc gtcgcgcagc gaggtgtcga gcagcacggc gacgacgggc agggcgatga
    22621 acagcagcac ccccgaaaca cggtgcgcga tcgatgcgat tgcaccgatc ggaaagcgga
    22681 tctgcgccag tttcaggaat accggcaagc gacgaggatg cctgtccatg tgggctcccg
    22741 ggcagttcga gccgccgccg gtggcggcgg aacagcgctt acccgaacca tagaccatag
    22801 gccggtgtgg tgccggcgtc ggtgcggtgc gccctacgat gaccgcgcgt ccgacgccga
    22861 tccgctgcct tcgcgccaca gccagatgga cgtgatcgcc agcagcaggc cggctgacgc
    22921 gctcgccacg cccagcgcat ccaggccggc aacgcgcgtg tcgccgacga ggcgcaccag
    22981 cagcggaccg gcgatctgtc cggcggcgaa gccggtggtc atgcgcgcca gcagcggcgt
    23041 cgggttcgcg ggcatgcgct cgcgcgcgag ttgaaggccc gccatcgtgg tgaccatgaa
    23101 ggtgccgccg accagcaccg ccgaggccgc cagcacccac aaggccggct gcagcagtgg
    23161 cagcagggtg cccaccgcca tcaccccctg cgcgatcgcc cacaccttgc gacgcggcca
    23221 gccgtgcagc cggtgcgcgg cgaaggccac ggacaacacc gccgccatgc cgaagatggg
    23281 ccaggtgagc ccgaacacga gcggatcgga caccagctgc cgcgccatcg tgggcaggaa
    23341 ggtcgcggga atgatgtagc cgaagccgaa cgcgctgtag cacagcacca cccccaggtt
    23401 tccgcctgcg actgcgggcg ctgcggaccg cggcgcgccc gccacgccgg ccacgggcgc
    23461 gacggcgggc tgcccgcgca cacgccgcat gacctggacc gcgccgaccg tggcgagcag
    23521 cccgagctcc acccacagca cgctcgccgc ctgcgcgccg cccagccagg tcagcacgcc
    23581 ggtggccgcg atgcccagcc ccaccccggt gtagatccag ccccccagcg aggtcgcgtg
    23641 ccgacgcgcg agttcgggca gacaccagct gctggcgcac accagcaccc acgcgctgaa
    23701 gacgcccgcg ctgccccgca gcgccatgcc cacccacggc agcgcggnnn nnnnnnnnnn
    23761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    23821 nnnnnnnnnn nnnnnnnnnn nnnnnnngcg ctgaagacgc ccgcgctgcc ccgcagcgcc
    23881 atgcccaccc acggcagcgc ggcgttgccc caggccatcg ccagcgtggt cgcggcgacg
    23941 ccgaccagcc cgacctgcaa gcccagccgc gggctgcgcg caaaccacga ggcgctgatc
    24001 gcgccgagca ggtagccgac gtagttcgcc gtcgcccatt ccgtcccggt caccgcgtcc
    24061 aggctgccgt cgcgcaccat cagcggcatc atcggcgtga aggcgaagcg gccgatgccc
    24121 atcgcgatcg cgagcgcgac gagtccgatg aagacgatcg atcggggcga gagggacgat
    24181 gaagagtggc gtttcatggc gagattagac tccgatcggg gcgcggacgg tacgtaatgc
    24241 cgacgattcc tcgaccccgc tcccggcgcg acatcgtggc cggcgtcgtt gccgtagccg
    24301 gcgtggacat catggctatg aggctcctcg aaattgaggt catcggcgcg tccgttcagc
    24361 ggcacttcaa cgtcgaagtc cggatggact cggaaccggt caaaagctag agtatcgaaa
    24421 ggtatcacta cgtgataaga ggcctaccat ggcaacgtct ctcaagatcg acgacgcact
    24481 gaagagccgc gttcagcacc tggccgcaca gcgccgccgc tcggcgcact ggatcatgct
    24541 cgaagccatc cagcagtacg tcgagcgcga ggaagcccgc gagagcttca cccaggaggc
    24601 cctggcgtcc tgggcagcgt acaaggaaac tggccgtcat ctgagcggtc aggaagtccg
    24661 cacctggttg aacacctggg gcaccgctga cgaaagtgcg gtgcccaagt gccacaagta
    24721 atcgtcaccg agcgcgcagc gcaaggtttg gagcgctgcc ggcgcttcct cgttgcgcgg
    24781 gcccccgaag ccgcccggcg cgcaggacag gccatcgcgc gccagctcct gttgctggag
    24841 acggcccccg acattggccg gccgttaccg gaaatacccg agttgcgcga gctggtgatt
    24901 gccttcgggg actccggata cgtcgccctt taccgccacg agccagcgga cgacgcggta
    24961 tacgtgctgg ccttccgtca ccagaaagag gcggggtact gacggacagg tgaacatgct
    25021 gctgcacggg gtgaaggatt ccgagtttga gatcttccac ggcgacaccc tgctcaacga
    25081 gtgggacatg ctgcgagaga cgaacccggc ccggatgccg aagttcgacg cggtggtggc
    25141 caatccgccc ttcagctatc gctgggagcc gagcgaggcg ctgggcgagg atgtgcgctt
    25201 caagaactac ggcctggcgc ccaagtctgc cgccgacttc gccttcctgc tgcacggctt
    25261 ccactttctc aagcaggacg gcgtgatggc catcatcctg ccccacggcg tgctgttccg
    25321 cggcggcgcc gaggctcgca tccgcaccaa gctgctgaag gacggccaca tcgacaccgt
    25381 gatcggcctg ccggccaacc tgttcttctc gaccggcatt ccggtctgca tcctggtgct
    25441 gaagaagtgc aagaagcctg acgacgtgct gttcatcaac gccgctgagc atttcgagaa
    25501 gggcaagcgg cagaaccagc tgctgcccga gcatatcgac aagatcatcg agacatacca
    25561 gttccgcaag gaagaggcgc gctactcgcg gcgggtgggc ctggcggaaa tcgagaagaa
    25621 tgatttcaac ctgaacatct cgcgctatgt cagcacagcg gaggcggaag aggaaatcga
    25681 cttggccgct gttcacgccg agctggtgtc gctggagcag aaaaggaaag ctgcgctcga
    25741 taagcacaac gcctttctca aggaactggg gttgccgatg ctgccgtgag ggcttcatcc
    25801 gggtggtgat ggtcgggacg ggaatcgact taacgggaag ccgggcgtct ggtaaagcca
    25861 ccggcagcga tttgttgctt tgctaccagt gggtatcggt gcttggatga cgatagaggc
    25921 cgtcgacgct ccgtccatcc ctgccggaag cagcgcgtgt tccacgtcac ttcccgctca
    25981 cgcgggtcgt cgatcgcctc cgcgggaacc tttccccccg ctccacgagt ccgagacgca
    26041 ccccgcccac taaaatggcg gcttccgtct ccgcctcgct cccatgcccg cctccacacc
    26101 ccgctacacc ccgatcgacg cccccgcctc gatcgccgac gccatccgca tccgcggtgc
    26161 gcgccagaac aacctgcgca acctctcgct cgacctgccg ctcaaccggc tgacggtggt
    26221 gaccggcgtg tccggctcgg gcaagtcctc gctggtgttc gacaccctgt acgccgaggg
    26281 tcagcggcgc tacgtcgaga ccttctcgcc ctacgcgcgc cagttcctcg accgcatgga
    26341 caagccgcag gtggatcgga tcgagggcgt gccgccggcg atcgcgatcg accagaccaa
    26401 cccggtgcgc acctcgcgct cgacggtggg cacgatgacc gagctcgccg accacttcaa
    26461 gctgctgtac gcgcgtgccg cgcacctgca ctgccgttgc tgcggcaagc cggtgcggcg
    26521 cgattcggca gtcagcatcg ccgccgacct gcgcgcgcgc gcggcggcgg cgggcgatcc
    26581 gcgcctggtg gtgtgctttc cggtgactgt gccgtcgagc ttccgcgagg cggaggtgac
    26641 cggcctgctc gccgcgcagg gctacacgcg catccaggaa cgcctcgccg gggccggtgc
    26701 cgaggggcag gacgtgctgc aggtggtgca ggaccgcttc cgcgcgtcga acgccgagga
    26761 tgcgcgcctg gccgaggcgc tggaggcggc gctgcagcgc ggtcatgggc ggcttgccgt
    26821 gtatgcgtcg ggcgaggggg tgaaggccgc ggcgacggag ggcacgccgg gcgaggcggt
    26881 gtggcgctat tcgtccggac tgcattgcgc ggactgcgac atccattatt ccgaggccac
    26941 gcccgggctg ttctcgttca actcgccgat cggtgcctgc gagacctgtc gcggcttcgg
    27001 gcgggtgatc ggggtggatt tcggcctggt ggtgccggac gagtcgaaga cgctggccga
    27061 gggtgcggtg aagccctggc agaccgagag ctatcgcgag tgccagcagg acctcgagaa
    27121 gatggcgaag aaatacggcg tggcgatgga catcccggtg cgcgacctgc cgccggagca
    27181 ccgccagtgg ctgttcgagg gcgacccgaa gtggaagaac tgggacagct cgtggccgcg
    27241 ctactggtac ggcgtgcgcc acttcttcga ctggctggag accaaggcct acaagatgca
    27301 catccgcgtg ctgctgtcgc gttatcgcag ctacacggag tgtccggcgt gccatggcgc
    27361 gcgcttgaaa cccgacgccc tgctgtggcg cctgcctacc agcggggaag cttcaggcag
    27421 gagcggcggc agccgcgaac agggcgtcga tgacggatgt gccttcggag ccgccgtatt
    27481 cgcggctgcc gccgctccta cagggggggc accaagcgtc cgtgaggatg gcgaggtcgg
    27541 tgcggcgaat gcggtatcgg aggcatcaag cgccggcgag gatgccgagg tcggtgcggc
    27601 gaatgtggca gcgggggcac caagcgccgg tgaggatggc gaggtcggtg cggcgaatgc
    27661 ggcagcgggg gcaccaagcg tccgtgagga tggcgaggtc ggtactgcga atgtggcagg
    27721 tggggcattc aacgtcggcg gggcgaacgt tctagccggg gcgtcgatcg tcggggccga
    27781 ggcccccgtc ggtgtggccc tagcggggtc ggttgcgcgc ggatccggcc tcgccatcca
    27841 cgagctgatg gccctgccgg tcgatcgcat ccgcgacgcc atcgccgcgc tcgcgctgcc
    27901 gggcgcggcg gacgaggcca ccgagctggt gctcggcgag atccgcagcc ggctcaccta
    27961 cctcgccgac gtcggcctcg gctacctgac gctcgaccgc cagtcgcgca cgctgtcggg
    28021 tggggaggtg cagcgcatca acctgaccac cgcgctcggc acctcgctgg tgaatacgct
    28081 gttcgtgctc gacgagccct cgatcggcct gcacccgcgc gacatcggcc gcatcctcgg
    28141 ggtgatgacg cggctgcgcg acgccggcaa cacgctggtg gtggtggagc acgacccgca
    28201 ggtgatggtg gccgccgacg agctgctcga gatcggtccc ggcccgggcg agcgcggcgg
    28261 cgacatcgtc gcgcgcggca cgccggccga gatcgccgcc aactcggatt cggtcaccgg
    28321 cccctggctc gccgggaaga agcgcatcga cgtcgatcgc ccgccgcggc cggtggacgc
    28381 cgccacgccg cggctgaagc tggtcggcgc gcgccagcac aacctgcgcg acctgaccgt
    28441 cggcttcccg ctgctgcgcc tcacctgcct gaccggagtg tccggctcgg gcaaatccac
    28501 gctgatccag gacgtgctgt tcccggcgct ggccaagcat ttcggcgagg cgaccgaatc
    28561 gccggggatc ttcgatcgtc tcgagagtgt ggataacttg cgcggcgtga tcatggtgga
    28621 ccagtcgccg atcggcaaga gctcgcgctc caacccggtg agctacgtcg gcgcctggga
    28681 cccgatccgc gccctctatg ccgccctgcc ggaggcgaag cagcgcggct acactcccgg
    28741 caccttcagc ttcaacgccg gccacgggcg ctgccccacc tgcaccggct cgggcttcga
    28801 gcacgtcgag atgcagttcc tgtccgacgt gtggctgcgc tgcccggact gcgacggcaa
    28861 gcgctaccgc ccggaagtgc ttgaattgca atggaacgga ctgtcggtgg cggatgtgct
    28921 ggcgctcacc gtgcatgagg cgctggacgt gttccgcgag catcccaagg tgctcgccgc
    28981 gctcgcgccg ttggccgacg tcggcctcga ctacctgcgc ctcggccagc cggtaccgac
    29041 gctgtcgggc ggcgaggccc agcgcctgaa gctcgcgggc cacctcgccg aggcggcaca
    29101 gaggaagcct gtacgcaaag ccagtgctgt ggataagttt gggagtaaag ctggggacaa
    29161 ggcgaacgga cttgccgtgc gggctggcag aggcaccccg ggcggggtct cctggctgac
    29221 cgagccagct gaacccggcc tgctcttcct tttcgacgag cccaccaccg gcctgcactt
    29281 cgaggacgtc gccaagctgc tcggcgcctt cgacaagctg ttgcaggccg ggcattcgct
    29341 gatcgtgatc gagcacaacc tcgacgtgat cgccgcgtcc gactggatca tcgacctcgg
    29401 ccccgagggc ggcgaaggcg gtggtgcgat cgtggtcgaa ggcccgccgg aagtggtgcg
    29461 cacacacgcg agctcgcaca ccggcgccgc gctgcgcgac tacgccgagg cgctgaagga
    29521 aataggggac agaccccaat ttctcgggca ccccgttccc gttcccggcg agcgctcgtg
    29581 taggagcggc ggcagccgcg aacctgcctc cgcgaatgat ggcgctgccg taggcgccat
    29641 gttcgcggct gccgccgctc ctgcaggggg gctcgtggcg gcggagccgc gggtggaata
    29701 ccgcccggtc gccgcccccg ccatcgagat ccgccacgct cgcgagcaca acctcaagaa
    29761 cgtcagcctg cagatcccgc gcgaccagtt caccgtgatc accggcctct ccggctcggg
    29821 caagtccacg ctggccttcg acatcgtctt cggcgagggt cagcgccgct acctcgaatc
    29881 gctcaacgcc tacgcgcgcc agttcgtgca gcccgccagc cggcccgacg tagatggcct
    29941 gttcggcatc ccgcccacgg tggcgatcga gcagcgcacc agccgcggcg ggcgcaagag
    30001 cacggtggcg acgctgaccg agatccaccc cttcctgcgc ctgatgtacg tgaagctggg
    30061 cacgcagttc tgccccgact gcaacgtgcc ggtgacgccg cagagcttcg aggccatcgt
    30121 cgcgcaggtc cagcgcgagc tgcgcggcgc ctcggtcgag gtgctggcgc cgctggtggt
    30181 caaccgcaag ggcctgtaca ccgacctcgc caagtgggcg cgcggcaagg gccacgcgca
    30241 gctgcgcgtc gatggcgagt acctgcccac caataaatgg ccgcgcctgg accgctacaa
    30301 ggagcacaac atcgagctgc ccaccggcat ggtggtggtg cagccggagc atgaggccac
    30361 gctgcgcgag ttcgtgcgcc aggcgctgga catcggcaag ggcgtgatca aggtgctcga
    30421 gatcggcaag ctcggcgcgc agccgatcac cttctccacg ctgcgcgcct gcccgagctg
    30481 cggcaccggc ttccccgagc ccgatccgcg cctgttctcc tacaacgcca agcacggctg
    30541 gtgccccaag tgctacggta ccgggctgaa gaccgcggcg cgcatcgagg acccggacgc
    30601 gctcgacctc ggcgatgcgg aggaggtcat cgtcagcgac gagccctgcc ccgcctgcga
    30661 gggcgcgcgc ctcaacccgg tggcgcgcgc ggtgcgcttc cgcgagctcg gcctgcacca
    30721 gctcgcggcg cagccggtgg acaaggcggc cggcttcttc gccgatctgg cgctcaacga
    30781 gcgcgaaacc gacatcgcgc gcgacctcgt cagcgagatc cgcgggcgcc tcgccttcct
    30841 gcagcacgtc ggcctcggct atctggcgct cgaccgcgcc gcgcccacgc tgtcgggcgg
    30901 cgaggcgcag cgcatccgcc tggcggcgca gctcggctcc aacctgcgcg gcgtgtgcta
    30961 catcctcgac gagcccacca tcggcctgca tccgcgcgac aaccgcctgc tgctcgacac
    31021 cctcgaggcc ttgcgcgacc gcggcaacac gctgctggtc gtcgagcacg acgaggacac
    31081 catccgccgc gccgaccacg tcatcgacct cggccccggc gccggcgtac gcggtggccg
    31141 cgtggtggcc gagggccgca tcgacgacct gctggcagcg cccgaatcgg ccaccggcga
    31201 gtgcttccgc cacccgctgc agcacccgct gcgcccgcgc cgcgcggtgg cgctggagaa
    31261 cccggcgatc cgcatcgaag gcgcgaacct gcacaacctg cgcggcgtcg acgtgcgcat
    31321 cccgctcgcc cgcctcaccg tggtcaccgg cgtgtccggc tcgggcaagt ccagcctggc
    31381 gcgcgacgtg atccacgcca acctgcgcgc ccgcctcggc gaccccgagg ccacgcgtgc
    31441 ccgccgccgc ggccaggcgc agccggaggc ggtcgaccag cccctggtcg gctgcgcggc
    31501 gatgcccggc tggcatcagg tgggccgcgt gctggaggtc gaccagaccc cgatcggcaa
    31561 gacgccgcgc tcctgcccgg ccacctacgt cggcttctgg gacgcgatcc gcaagctctt
    31621 cgccgacacc ttcgacgccc gcacgcgcgg ctggaacgcc tcgcgcttct ccttcaacac
    31681 cggcgccggg cgctgcccgg tgtgcgatgg cgccggccag accaccgtcg agatgagctt
    31741 cctgcccgac gtgaagacgc cctgcgaggc ctgcggcggt gcgcgcttca accccgagac
    31801 gctgtcggtg cgctggaagg acaggaccgt ggccgaagtg ctggcgatgc cggtggacga
    31861 ggcggtggac ttcttctccg cgcatccggc gatcgcccac ccgctgcagc tgctgcagga
    31921 cgtcggcctt ggctacctga ccctgggcca gcccagcccg acgctgtcgg gcggcgaggc
    31981 gcagcgcatc aagctcgtca ccgagctcgc caaggtgcgc cgccgccccg gcgatgcgga
    32041 cgacaccggc ggcgtgccgc tgcccgccga caagcacagc ctgtacgtgc tcgacgagcc
    32101 caccgtgggc ctgcacatgg ccgacgtgga caagctcatc cgcgtgctgc accggctgac
    32161 ggatgccggc cacaccgtgc tggtgatcga gcacgacctc gacgtgatgg ccgaggcgga
    32221 ctggctgatc gacctcggcc cggaaggcgg cgacggcggc ggccgggtgg tggccgaggg
    32281 cccgcccgag gtggcgatgg cgacgccggg atcgcatacc ggacggcatc tgcgcgagtt
    32341 cctggcgcag cgcaaggtcg gatgatgcag tgcagcggaa cctcgccggg atgatccggt
    32401 cctgaaaggg gatggcgcta caagccgaaa tacggggcgc catcccgggc tgcgataatc
    32461 cgctcgatgc cgaacgcggc cgaaacccca ccgtcgaagg gaagacaatt gatgaacacc
    32521 cgcaagatcc gcgtctggga cctgcccacc cgactcttcc actggctgct ggtcgtgctg
    32581 gtgcttgccg cctacgtcac cgggcagatc ggcggcagca tgatcgagtg gcacggccgc
    32641 gccggcgtgg cgatcaccgg cctgctcgcc ttccgcatcg tgtggggcat cgtcggctcc
    32701 acctacgcgc gctttgccga cttcgtgccc acgcccggcc gcatcggcag ctatctgcgc
    32761 ggccagtgga accgccccgg ccacaacccg ctcggcgcgc tgtcggtgtt tgcgctgctg
    32821 gcgatcctga tcttccaggc ggtcagcggg ctgttctcga acgacgagat cgccttctcc
    32881 ggccctctgc gcgagctggt gagctcggag accagcgagc ggctctctgg cctgcaccgg
    32941 cagaactact gggtcatcct cgccttcgtc gtgctgcacg tcggtgcggt cgtgttctac
    33001 gcgctggtga agaaggacga cctcgtcaag ccgatgatca ccggggtgaa ggaagtcgcc
    33061 gacccggcgc acgagcccgc ccgcggtggc ggcacggtgg ccttcatcgt cgcgctggcg
    33121 gtcaccgccg cggtgctcta cttcgccacc ggcagcttca tcgagccgcc tccgccgcca
    33181 ccgcctgcgg cgtggtgatg tgaagattcg cggctcgcgc cgtccctgca gggattccgg
    33241 cgcgccgcgt cgcccggcag gagcatcgca agccgcgcgc ccctgcgtaa aacggcgaag
    33301 ccaccccgcg gggtggcttc gccgttcaag cgccttacac ctggcgcttc actccatccg
    33361 gtacttgtcg tgacaggcct tgcaggtctc gccggtcgcg ccgaaggcct tctgcaccgc
    33421 ggccttgtcg ccggtggcgg cgaccttcgc gaggttggcg gcggcgttgt tgaagtcggt
    33481 ggcgagcttg ccgacgttcg gcatctcctg gaagaactcc ggcttgacgc gggtcttgag
    33541 gctgccgatg tccttctcgg tgcccggacc gtagagcgca cccatgcccg agccggcgat
    33601 gccggcgatg gcggtggcgg cggcctggac ctgctgggcg ttgtactcac cctcgaggtt
    33661 ggccttgatc ttgcccatgt tccagctcat gaagctgtag ccggcctggc ggaacttgat
    33721 ctggtcctcg ggcttgacct gggccgaagc cgcggtggcg agggtaaggg agaggatgcc
    33781 gagggcgatt gcttttttca tcgtgagcct cctgagtcgg ggggttaagg aaggaacaaa
    33841 gcttgcaagg aactgcgcag acaaggatgc gccctggcag ttccatcgtt gttgcatgcc
    33901 ggaatgcacc tgccagcacc aagcttatat cagatttttt cgatattcct tcgtcagctc
    33961 gtgttgcggc gcgacagcag cgcgctcaag ccggggcgtg cgcggccgta agacaggagt
    34021 agagggtgcc tgtccgcacg ccgcccaccg tccgcaggac cgcgagaacc aagatgatcc
    34081 gattttccga tactcccatt tggctgcgcc tcaccggcgc gatctggctg atgatggtgg
    34141 ccgcgttcgg cagcatgatc gtctgggaga cgcgggtgaa ccgcgacatg gcgatcgagc
    34201 aggcgaagga ctttgccggc acggtcaacg agatgaccat ggccggcctc accgggatga
    34261 tgatcaccgg caccgtggcg cagcgcgacg tcttcctcga ccagatcaag gagctcagcg
    34321 tggtgcagga cctcgaggtg atccgcggcg aggcggtgag ccgggtgttc ggcgggggcg
    34381 gcgcgctcga agcggcgcgc gacgccgacg agcgcctggc cctggtcgag ggccgcagca
    34441 cggtgcgggt cgaccacgac gccgagcatg gcgagcatct gcgcgtggtg atcccctcgc
    34501 tggcctcgac cgactggctc ggcaaggact gcatcgcctg ccaccaggtg ccgcaaggca
    34561 cgccgctcgg cgcggtgtcg atgcgcatct cgctcgacaa ggccaacgct gcggtgctcg
    34621 ccttccgcaa ccagagcgcg atgttcgccg cgctggtgtc gatcccgctg atcctgttca
    34681 tctacctctt catcacccgc ttcgtcaccc gtccgctcga cggcctcaac cagggcctgg
    34741 ggcggatcgc cgagggtggt ggcgacctgc ggctgcaact gccggtgcgc ggccgcgacg
    34801 agatcggccg cagcgcgcgc accttcaacg acatgatggg cacgctcagc gggctggtgc
    34861 gccaggtcgg cgactcggcg agcgcggtga cggaggcggc gagccggctc gccgccgatg
    34921 ccgaggcggt cgccgagagc tcgcagcgcc agaacgagag ctcgatgggt gcggccagcg
    34981 cggtggacga gatggtcggc agcatctccg cgatcgccga gcacgccgag gcggtgcgcg
    35041 agcgctcgca tgacagcctg gagcgctcgc gcgagggcca gcgcagcctc gagcgcctgg
    35101 tcggcgaggt gggcgaggtc gaggctgcgg tgcgccagat ggccgacgcg gtggtcgcct
    35161 tcgtcgactc cacccaggcg atctcgcgca tgaccagcga ggtgcgcgag atcgccgagc
    35221 agaccaacct gctcgcgctc aacgccgcga tcgaggccgc tcgcgccggc gagcagggac
    35281 gcggtttcgc ggtggtggcc gacgaggtgc gcaagctggc ggaaaagtcg gcgcgctcgg
    35341 cgggcgagat cgaccagatc acccgcgagg tggcaaggcg ttcaggctcg gtgcgtggcg
    35401 cgctcgacga cggcctcggc cacctggcct ccagccggca gatggccgac gcggtgatgc
    35461 aggtgcttgg cgcggcgaac tcgctggtgg tcgaggtcgg cgagggcctg gaccgcatcg
    35521 ccggcgccac cggtgcccag cgcaacgcga gcgagtcggt caccgcgcgc atcggcgaga
    35581 tcgccggcat ggcgcgcagc aacaacgacg cactcgcgca tacggtgcag tcggcgcgcg
    35641 agctcggcga gctcgccgta cgcctgcagg agtcggtgtc gcgcttccgc ttctgagcgc
    35701 gcccacggcg ctggatatga acagggcggg aaccgttgcc ggtcccgccc tttgtctgca
    35761 agcggctcag tgtggggcga tcactccagg cgcaccggca cgaagatgcg tgcctcgccg
    35821 cgctggatca gcagcgcgaa gcgcttgccg gcgcgctcga gctgggcgcg cagctcggcg
    35881 acgctcagca ccggctggtt gttgatcgcc aggatcacgt cgccgcgctg caggccggcg
    35941 cgcgcggagg cgccgtcggc gccctccacc atcaccccgc cgcgcagctg cagccgggcg
    36001 ctctcttccg cgctgagcgc gcgcgcgctg aggccgaact gctcgcccag gcgctccacc
    36061 tggctgggcg ccggcgcatt gccggccacg gtctcggcct tgagctcgtc cagggtggcg
    36121 gcgacctcgc ggctgcggcc gtcgcgccaa agctccagct tcacgcgcgt gccggggcgc
    36181 ttctcgccga tgacccgcgg cagctcggcc gagtcgtcga tgcggcggcc atcgaccgcg
    36241 agcaccacgt cgcccgcctg cagcccggcc ttgtcggcgg cgctgcccgg ctcgacgctg
    36301 gcgaccagcg cgccgcgcgg gtcggggagg ccgaaggatt gcgcgaggtc cttgtcgacg
    36361 ttctggatgg cgatgcccag ccgcccgcgc tgcacgcggc cgtggctgac gagctggtcc
    36421 ttgatgttca tcgcgacgtc gatcgggatc gcgaacgaga tgcccatgaa gccgcccgag
    36481 cgcgagtaga tctgcgagtt gatgcccacc acctcgccgg cgaggttgaa cagcggaccg
    36541 cccgagttgc ccgggttgat cgccacgtcg gtctggatga aggggacgta ggtctcgtcg
    36601 ggcaggcggc gtgccttggc cgagatgatg ccggcggtga cggtgttgtc gaagccgaag
    36661 ggcgagccca tcgccaccac ccattcgccc acgcgggcct ggtcggggtt gccgatcttc
    36721 accgcgggca ggccggtggc gtcgagcttg agcagggcga cgtcggtgcg gcggtcgatg
    36781 ccgaccacct tggccttgaa ctcgcgcttg tcgatcaggg tgacggtgac ctcggagagc
    36841 tcggcgtcgc cgtcctcgcc ggcgaccacg tgggcgttgg tcagcacgta gccgtcctgg
    36901 ctgacgatga agcccgagcc gatgccctgg cgtgcgcgcg gccccatgcc gggctggccg
    36961 gggaagcccg gcatgggcac gccgaagcgg cgcaggaagt cgtagaaggg gtcgttggcg
    37021 agggggttct cgcccgccgt gccctgcgcg gcgcgctgca ccacgcggat gttgaccacc
    37081 gccgggccga cctgctcgac caggtcgccg aagtcgggca ggccgaagcg gttgggcgag
    37141 accatcgacg gggcggccgc ctgggcgtgc gcggcgggga gcaccgaggc ctgggggaag
    37201 atcgtgccga gcgcgagcgc gacggcggtg acggtcagga atttgcgcat gttgttgggc
    37261 atccttgttc ggcaacggag atgttcggcg ccggcgtccc ggcggccact tgtcgtggac
    37321 gcggccaggc gcgcgccgtt cccggtgaaa cctgcgtttt cacatcgggg cgggcgcggg
    37381 cgcttcaagg gggtgcgttc agaaagtcgt ctccagcgcc atccacacct ggcggctcac
    37441 ctggctggcg ggccgtccgg cgaactcggc ctgcgcctgc agggggcgat tggcgagttc
    37501 ctggtggcgg ccgagcaggt tgatgccggt gaggcggacc tcgacggctt gatcgagcac
    37561 gcgcaggctg cgcgcgatgc tccagtccag cgtggtatag gacggcacgg tgtagttgta
    37621 gccgggcaca tagctgaagc cggcgtcgat cggtcccatg cgcagcacgc tcagcatcga
    37681 gcgccacgcc ccggcgcgct gcagccagct caggctggcg ctgtaggggg agacgttgcg
    37741 gcggatgcgc gggtcgtcga tatcgcggtc gatgaggctg tgcgagagga tgaactcggt
    37801 gccgcgccag ggcttgaggt ggagctgggt ctcgatgccg ttcagctgca cgcggccggc
    37861 gtggttctcc cagcgggtgc tgccgaacat ggcgctgaac aggctggggg gaacctgccc
    37921 cgcaggcacg ggactgcgca cgatgacgtc gtcgatgcgc tcgcggaaca ggcgcacgtc
    37981 cagcgtgctg cggctgtcgc cgaacacgcc caggaagccg atctcgctgg cgtcgatgcg
    38041 ttgcgggcgc agcgcggggt tgggcagctg gcgatactgc agcggtcgac cgaggtcgtc
    38101 gatgacgcgc acgtcggcgt tgcgctcgaa cagcaccggc tggcgccatg cgcgcgagtg
    38161 gccgatgcgc caggtgaagc ggggtgtggc ctgccagttg aggaacacgc gcggtgcgaa
    38221 gcgtgcctcg tcaccctgca gctgctcgat catgccaccg aggttccaca gccaggccgg
    38281 cgcagcgcgc cattcgaggt tggagaacag gcgatgctcg ttgcgcgcgt gcctgccgct
    38341 ggcgtgatag aagaacgccg actcgtcctg ggtacgctgc cattccgcac cccacatcag
    38401 gcgggtgtcg gcactcacgc gcaggcggtg ttcgagctcg aggttgtgct gggtgtactg
    38461 tgcgtcgttg cccaccgtgg cctgcactct cccgagctgc ggcgggggct ggaagccggg
    38521 gggcggattc agcgccgaat cgaggcgcca gcgctcgcgc atctgctggc cgctccaata
    38581 cgcggagagc agccactcct cgtcctcgtg cggcgtgtgg cgccagcgca ggtggagcga
    38641 gcggttgtgc ttgtgcccct cacgctcggc ggcggtgccg aagatcgagc cggcatagcc
    38701 gagctggtgc gtgctctcgg cgacgccggc gatgaggccg agctcgttgg tcgcgtccac
    38761 gcgcaggtcc gcacgcaggt tcagcacgtc cgtgcggcgg ccgtcgtaca ggtcgtcgaa
    38821 gccatcgtct tcctcgtggt gggcgccgat gcgcaggctg agcggccctg cctgcgcggc
    38881 gtggcgcacc ccggcatcga ggatgcccgg cgctccggcg gcgagcttca ggcgggtgcc
    38941 gggcgtgcgg ctggcgtcgt cggtggtgat gttgaccacg ccgaggaagg cattggagcc
    39001 gtaggcagcc gagttcgagc cgcgcaccac ctcgatgcgc tcgatgtcgc ccggcagggc
    39061 acgctcggcg ctggcggcga aggatggagt gagcgaggcg cgcccgtcga ccagcaactg
    39121 catctgcacc gggtagtcca tgcccaggcc gtggtaggtc acccactgca cgttgccgcg
    39181 ctcctggccg acctggaagc ccggcaccag ccgcagcacg cgcgcgagct cgcggtagcc
    39241 ggtggcggcg atcaggtcgg cgtcgatcac gctgaccgcg cccgggctgt cctgcagcgg
    39301 ctgcgcgagg cgcgacgcgc tcagcacgac cggcaggggt tcgaagaagg ggttctcggc
    39361 cgacgcccag gcagcgctgg ccgtcagcag caggacgagg gcgacgcggt gcgggtgaag
    39421 agacatcgga agcgggcggc tacacgtaag gcgcgagtat accgactgcg cgctcgggca
    39481 cgcagcaacg atcagtcgcg gtaacatcgg acatcgtcga ttccgggtgc aagcccagcc
    39541 atcgtgtcga agccatgacc ctgaccgatc tgcgttatct cgtcgcgctc gcccacgagc
    39601 gccatttcgg ccgtgccgcc gaaaagtgcc acgtgtcgca gcccacgctg tcggtggcgg
    39661 tgaagaaggt cgaggaggag ctcggcatcc agctcttcga gcgcagcgcc tcggaggtca
    39721 agatcaccga gaccgggcgg cgcatcgtcg cccaggccga acgcgtgctg atggaggcga
    39781 gccagatcca ggagatcgcc gccgccggca aggacccgct cgccggcccg ctgcgcgtgg
    39841 gcgtgatcta caccatcgga ccctacctgc tgccgcggct gattccgcgc gtgcatcagc
    39901 tcgcgcccag gatgccgctg atcatccagg agaacttcac cgcccggctg gccgaggcgc
    39961 tcaagcgcgg cgagctcgac gtcatcatca tcagcctgcc cttcgacgag gcgggggtag
    40021 tggcgcagcc ggtgtacgac gagcccttcc gcgtgctgat gccggcaggc catgcgtgga
    40081 acgcggagaa cgagatcgac ccccagcatc tcgccgacga ccagctgctg ctgctcggcg
    40141 ccggcaactg cttccgcgac caggtgctcg aggtgtgccc gagctgccgc aacatcggcg
    40201 gcctgcagcg tacgctcgag ggcagctcgc tcgagaccat ccgccacatg gtcgccaccg
    40261 gcctcggcgt caccgtgctg ccgagctcgg ccgcggacga gatggcgacg cagaacccct
    40321 tggtcgcggt gcggccgttc tcgcagccgg agccctcgcg ccgcgtcgcc ctcgcctggc
    40381 gcgtgaccta cccgcgcagc ggcgcgatcg acgtgctgcg cgcggccatc ctcgacagcg
    40441 cgctgcccgg cgtgacgccg gtggggcggg ccatgtcccc cgcgtcggtg ctgcgagcgg
    40501 atttacgatg acaattcttg atcggatcga tcaggacaat cggtttgatc aatgcatccc
    40561 tctggcgcta acatgaagcg catacccctg cgggccgtgt gaagcctgcc atacacagga
    40621 gaaccagcat ggaaatcgat atcggcatca aggaaaagga ccgtgccaag atcgcggaag
    40681 gcctgtcgcg cctgctcgcg gacagctaca ccctgtacct gaccacgcac aacttccact
    40741 ggaacgtgac ggggccgatg ttcaacaccc tgcacctgat gttcgagacg cagtacaacg
    40801 agctcgcgct cgcggtcgac gagatcgcgg aacgcatccg cgcgctcggt ttcccggcgc
    40861 cgggcaccta caaggagttc cagaagctca ccagcatggc cgagccggaa ggcgtgccga
    40921 gcgcgcagga gatgatccgc ctgctggtgc agggccagga ggcggtcgtc aagaccgcgc
    40981 gcagcatcgc ccccatcgcc gacaaggcga gcgacgagcc cacgctggat ctgctgacgc
    41041 agcgcatgca ggtgcacgaa aagaccgcct ggatgctgcg cagcctgctc gagggctgag
    41101 cgctcgtcag tttgctgcat ggaacacgac ggacccgctg ggtccgtcgt gtttccggct
    41161 tgcgaatcac accgcttcca cgagcgcgct tgacacgggc atgcttggga tagcggccgg
    41221 cgcgaacggg cgtctgcgct gatccgctcc tccaccttcg cgcctgcccg cgctcctgca
    41281 cgaaccgcca cgcgccctca gccccctgta ggagcggcgg cagccgcgaa gggtgccgtc
    41341 cggcggttga cgtggtcgca ggtcattcgg cgcggccgcc ttcgcgcctg ccgaagcatc
    41401 gcgctcgacc gcctccttgt aggagcgccg gcaggcgcga atgcggcggc cgggctgcga
    41461 tgcccccggg tgcgccggac tacccggcct tggccgcgtt gaggcgcttg accgcattga
    41521 cgaagcgcga cagcgactcc gacagcacgc cgcgcgggat catcacctcg atcagctgga
    41581 agcgtccgcg cgtggtgatc gcgcggtcga gcgcggcctt caactccgcc cgcgtgcgca
    41641 cgcgcacacc gtctcccccc agtcccgcgg ccatctgcgc gaaaccccag tcgtcgaggt
    41701 cgttgaagcc cgactcgggc tggaaggtgc gcagcatctc ccagctcgcg ttgttgaaca
    41761 gcagcacgat cggatcccag ccgtagcgcc tgcagttgcc gagctcccag ccggtcatct
    41821 ggaaggcgcc gtcgccgacc aggatcagcg gccgctgtcc ggtggccgcc tgcacgccga
    41881 ggccggccgg cacgccgaag cccatggtcg cgtagtagcc gggagcgacc agcgcggtgt
    41941 gctcgatgtc catcgcggta aacaggcagt cgcccatgtc ggaggcgatc ggcagcttgc
    42001 cgtgggccgc catcaggtca ttcaccgcgc aggcgatgtc ggcgggagcg atcgtcgcct
    42061 cgtccgccag caggccgtgc gggaaggcgg ggcgatccac gccgaagtgc gcctcggccg
    42121 gtgccacgcg cgcgagcagg ccgtcgacca gggcgtcgag cgggatgtcg gcgtaggtgt
    42181 ggtagcccat cgtgacccgg gcctcgagcg cctggatcgt gcggcgcagg tcgatgtgct
    42241 tgccggacac ggcgaagttg gtgtccgaga tgatcacccc gagcaggaac aggccgtcgg
    42301 aatcctccac cagcgcgctc acctcgggca ggccggcgag ccccatgtag gtgcccatca
    42361 gcggggcgtc gtgatcggcg aggaggccgc ggcccatgaa gctggtcacc accgggatgc
    42421 cgagccggcg cgagagctcg gcgaccttgt cctcgagggc gaagcggcgc acctccacgc
    42481 cggccatgag caccggcgcg cgggctgcac ggaggcggcc gaggatctcg tccacgcagg
    42541 ctgcgagcgc gtcggcatcg accgcacgcg gcgcctcgcg cagcaccggc gcgcacgggc
    42601 gggcgaccat gtcgcgcggg atctcgatat acaccggcaa cgaattgcgc acgcagttgc
    42661 cgagcacgcg cgcgatgtcg gccggcgcgc gtgcggcgtc gtccagccgc acctggtcgc
    42721 aggtgatctc ctggaagatg cggaactgcg agtccagcgt cttggcctgg tggtgcagca
    42781 gcagtccgga ctccgattcg cccaggcccg gcccaccgga gaggaccacc agcggcgact
    42841 tctcggcata ggcggcggcg accgcgttga tcatgttgag cgcgccggcg ccgtaggtga
    42901 ccgcagccac gccgatgctg ccctggacgc gcgcggccgc gtcggcggcg aagccaacgc
    42961 cgggctcgtg cgacagcgtg tgcagcggca ggatgccggt ctgctcgatg atgcggaaat
    43021 acggcagggc gaagtcgccc gggatgccga agatctgccg cgcgccgtgg tcgaccagcg
    43081 cgtgcagcag cgattcggtc aggttcatgc tcgtctctcc ctcgttgtgg tgaggaggat
    43141 tatcggtggc cggcctcgca ccgtgttcgc atcatgaggg tatagaatcg cccgatacgc
    43201 acggttcgtg catttcgagg ctggatgatg agcaccctga gcatagaccg ccacgatctc
    43261 gcacttctgg acgccttgca gcgcagcggc gacgcgacca atgccgtgct cggcgaggcg
    43321 gtgcatctgt ccgcctcgca ggtgagccgc cgcctgcagc gcctgcagga ggccgggctg
    43381 atcaccggct acgcggccct gctcgacccc gccgcgctcg ggctggacgt gatcgccttc
    43441 gcccacgtcg tgctcgaacg ccacggcggc gtgcgcaccg aggccttcga ggaaggcgtc
    43501 gcggccttgc cggaggtgct ggagtgcttc tcggtgagcg gcaacgcgga ctacgtgctg
    43561 cgcatcgtcg cgcccgacct ggccgcgttc tccgagctga tgatgaagcg cgtgctgcgc
    43621 ctgcccggca tcgccaacat caagaccgac atcgtgctcg gcaaggtcaa gcagacccac
    43681 gtgctgccgc tcgagcacat cgcccgcccg agccggcccc gccgcggcgt gcgctacagt
    43741 gcgggctgaa gcactcccgt aaaaagcgcc gccgccgcct tcgcgcctgc cggcgctcct
    43801 acannnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    43861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnncgccttc gcgcctgccg
    43921 gcgctcctac aggaaccgct gcggctcggg agcgcatgta ggagcggcgg cagccgcgaa
    43981 tacggcggtt tgtcctgtga cgtggaggac gcagccgcgg cggagagtct cagcccgcct
    44041 tgcgcgccgg cgcgcgcttg cgcggtgcgg cggccgcggc gccctcgcct gcggcttcgt
    44101 cgcccttggc cgcggtggtc ttcgcactcg ccttgggcgc cttggcctcg aactcgaagc
    44161 cgaccttgcc gtccttgccg cgcaccagga aggcggagaa cttgcgccgc gtacgcgccg
    44221 acacgaagcc cttgagcagc tccgtcttgc cctcggtcag cagcttggcc atctgctcgc
    44281 gctcgatcgg ctgctgcagg atgaccttgc cggagcggaa atcgcattgc ctgtccggcc
    44341 cgaccgactt ctcgcacaca taggccatgc cgtgctcgaa cacgcggctg gcgcatttcg
    44401 ggcaggcgcc gaccggctcc tgggccgaga agtccaccgc ctccgcctct tcgccctctt
    44461 tcggctggcc gaagtcgaag gtgggctgct tgtcctcgtt cagcacgatg tcggcgttga
    44521 agagccgccc catcttgttg cggaagccga gcagcgggcc gaccttgccc tcgcgcagca
    44581 gggtctcgat ctcgtcgtac tcgaactggc gaccggcgac gatcttccag gtgctccagt
    44641 cgcaggcctg gcaggcgaac ttcttgtagt tctccttcac cacgccgccg cacttggggc
    44701 acggcgtctg cagggtgacg aactcgcccg ggacggtgtc ggactcgtag cgcttggcgc
    44761 gctcgacgac ctcgcgcgtc atctccgcga tctcgttcat gaaggcttcg cggctgagct
    44821 tgccgtgctc catctgcgcg agcttgtatt cccagccgcc ggtcagctcc ggcgaggtca
    44881 gcgcgttcac gccgaggccc tttagcagcg tgatcagcga gaaggccttg gcgctcggga
    44941 tcagctcgcg gccttcgcgg tggatgtact gctcgctgat caggccttcg atgatctgcg
    45001 cgcgcgtggc tggggtgcca aggccgcgct cggccatcgc cgcgcgcagt tcctcgtcgt
    45061 ccaccatctt gcctgcgcct tccatggcgg agagcagcgt ggcttcgttg aagcgcgccg
    45121 gcggcttggt ctgcagcgat ttcaccacga tgtcctcggt ggacaccgtc tcgccctgct
    45181 tcaccgccac cagctgcggg ccgccgccct ctttgggatc cccgggtttc ccgtccttct
    45241 cgtcgctggc ggcttccttg ccatacaccg ccagccagcc cggattgacc agcaccttgc
    45301 cctcggtctt gaaggcctcg ccctcgacgc gggtgatgcg ggtggtgatc tggtactcgg
    45361 ccgccggata gaacaccgcc aggaagcgct tggtgacgag gtcgtagatc ttgtattcgg
    45421 cgtccgacag gctcttcggc agcgtgccgg tggggatgat ggcgaagtgg tcggagatct
    45481 tggcgttgtt gaagatgcgc ttgttcggct tcacccagcc ctgcttggtg atctcgttgg
    45541 cgaacggcgc gtactggtct ggcagggtgc gcatgacctc gctcaccgtg ccgaggtagt
    45601 cctcgggcag ggcgcgtgcg tcggtacgcg ggtaggtcag caccttgtgc ttctcgtaca
    45661 gcgcctgggc gagctgcagg gtgacgcggg cggaaaagcc gaagcggccg ttggcctcgc
    45721 gctgcaggct ggtgaggtcg aacagcagcg gcgacagttg cgtggagggc ttggcctcct
    45781 cggtcaccac gcccggcttg ccttcgcact tggcgcggat ggcctcggcc tgggccttgt
    45841 cccacaggcg gaaggcggtg gcgtgctcgt cgccctcggg ctttttgaac ttctcgtcga
    45901 accagcgccc cgggtattcg ccggcggcgc agccgaagcg cgcctcgagc tcccagtagt
    45961 cgcgcgactt gaacttgcgg atgcggtcct cgcgctccac caccatcgcc agcgtcggcg
    46021 tctgcacgcg gcccaccgtg gtgaggtgga agccgccggt cttggagttg aacgcggtca
    46081 tcgcgcgcgt gccgttgatg ccgatcagcc agtccgattc ggcgcggcag atcgcggcgt
    46141 tgcgcaggcc ctcgacgtcc tgcgcggcgc gcaggtgggc gaagccgtcg cggatcgcct
    46201 gtgcggtcat cgactgcagc cacaggcgct gcatcggctt cttgctgccg gcatgctggg
    46261 cgatgaagtt gaagatcagc tcgccttcgc ggcccgcgtc acaggcgttg atcaggccgg
    46321 tgacgtcctt ccgcttgatc agccgggtga gcagcttgag gcggtcctct gtcttctcga
    46381 tcggcttgac cgcgaagtgg ggcgggatca ccggcaggtg ggcgaaggtc cacttgccgc
    46441 gcttgacctc gaactcctcg ggcacggtga gctcgagaag gtggccgacg gccgacgaca
    46501 ggacgtagtc gtcggactcg aagtagtcct tctctttcgt gaagccgccc agcgcacggg
    46561 cgatgtcctg cgcgacggaa ggcttttccg cgatgatcag ttgcttgctc atgctcgacg
    46621 gtcaacgagg gtcgcgccgc gagggcgcgt gggttcggaa gcggcggatg ataaggacgg
    46681 cccgccggaa caggcaagcc gagcgggtgg accggtcagt gcaacgtggg ttcgtaggcc
    46741 cagtcgtctt cctcggtcag cagctcgtcc accatcaggg tgtcgatcgg ctcctcctgc
    46801 tgccacagca ccatcagcac gatgaccttg agccggttca gcgtgatggt gaagtcggcc
    46861 agcgccatcg cgcgctcgat gatcagttcg cggtgggcgg tgccgagcac gccggcgctc
    46921 tcgagcaggc tcaggaaacc gcggcagcgg ccgtcgagca gggcctgctc ttcttccgtg
    46981 tagatgcgca ccgacccggc ttgcggcgcg gtgccggggt ggatttcgcg ggcgacgcgg
    47041 cgcaggccgg cgagccactc cagcgcctcg gagatgtcgt cctgctcgaa gcccgcggcg
    47101 gacagcttgc ggttgagcag ttcgccttcc gggcaggcgt cggcgtggat gtagctctcg
    47161 aagaggtata cgaggatgtc gaacaaggcg gcctctcgtg gatcggcagg ggaggcggaa
    47221 gagccggacc cccgccgggg tgtggggggc ggcggctcgc ggccgctctt tcaggtggtg
    47281 cgctggaagc gtccgccggg cagcttggcc aggcgccctt ccagttcgag tggcagcagg
    47341 atggcgtaga gggcatcgac cgtcaagccg cagcgcgcgg cgatggtgtc gaggtcgacc
    47401 ggatcgtggc cgatcgcatc gagcacgcgc gcggtctcgc catcgagcgc gagcgcggcc
    47461 tgcaggggcg gttgggccgg ggcggcgggc tccgcgccgc ggcgctggcg gccccttgcg
    47521 cttgctgtgg gtgcgacgac cggcgcgggc cagccgaggc ggccgcgcaa ctcctcgacg
    47581 acgtcctcgg cggtctcgac cagcttggcg ccgtcgcgga tcaggcggtg gcagccgcgc
    47641 gacagcggcg agtggatcga gcccgggatg gcgaacacct cgcgcccggt ctcggtggcg
    47701 agccgggcgg tgatcagcga gccgctgccg agcgctgcct cgaccaccag cacgccctcg
    47761 gcgaggccgg cgatcaggcg gttgcggcgc gggaagttgt gctgcagggg cggtgtgccg
    47821 aggggaaact cgctgacgac cgcgccggcg gcggcgatct cgcgcgccag cgcggcgttg
    47881 cgcgcggggt agatgcggtc gatgccggtg ccgatcaccg ctaccgtgcc cgcagcttcc
    47941 gtgccggcgg cgagcgcgcc gcggtgcgcg gcggcgtcga tgccgagcgc cagcccgctc
    48001 acgacgacga ggccttgctc ggcaagcgcg cgcgcgaagg ccccggcgtt ggcttcgccc
    48061 gcagcggtcg ccgagcgcgc gccgaccagc gcgatgcccg ggcgcgacag cagcgcggga
    48121 tcgcccttga cgtagagcag caccggggga tcggcgatgt cgaagagctg gcgcgggtag
    48181 ccggcgtcgg ccagggtcag gatgtggttg ccggcctcgc ccgcccaggc gagcgcgcgc
    48241 tcgatgtctt cgtgtgccgg tgccgcgagc accgcgtcgg ccgctgtgcc gcccaccacg
    48301 gcggcgagcg cgccacgccc ggcggcaaag atgtggccgg gcaggccgaa ggcggcgagc
    48361 agggcgcgct ggccctgcgt tcccacgccc ggcacggcgg cgaggcgaag ccagtcggcg
    48421 agatcgtcgg caggcacggt cacgatgcgg cggctgcgac ccggcggtgc cggatcaggg
    48481 cttgcggacg gtgtcgccga tggtgaccgg gccgtcggat tccatcacca gcgcgtaggc
    48541 cacgcgctcg aagacgcgga agacgaaggc cacgccgtag cgcttctcgg gcaggcggaa
    48601 gctctccttg ccgtcctcgc cgcggtactc ggcgacaccg cggttgcggt agagggcgag
    48661 cacgtggccg cgctcgaggc cgtcctgctc gccggtgtcg agcgcgacca cgttgagtcg
    48721 gccggtctcg ctgaccccac ggtaaatgga gatgatgctg ccctcgacgt cgaattcagg
    48781 cgcgtgcggg gcgtaggaga acacgctcgg cggttcgctc ggcatcatca ggtcgccggt
    48841 gccgatctcc tcgaccgcgg agacgatctc cagcgtggtc ggttcgccgc gctcggtgac
    48901 gcgggcggtg ccgaggtagg cagcttccca ggcgatcggc gcgcgcgtgc gcgggtcctc
    48961 gagcgggcgg gccgggcgat agatgtgcca gacttcggcc tcgtcgccga cgttcttggc
    49021 gaagatggtg tcgccggtcc cggtcaggac gcggctggtc tcggtggcga cgatggtggc
    49081 cgagccgtcg aggcggggct ggtcgaccac cagcgggcga ttcaggaagg gctcgatgat
    49141 ctgcagcggg atgctgggca gggcctcggc gatcggctcg ttgtagaccc tcggctgcag
    49201 gcggccgtct gcagtgctgc caccgccgac ccggcggccg acgctgagcc aggggccgct
    49261 gcggtcgagc aggatgacct ggccggggta gatgaggtgc gggttgcgga tctcgtcgcg
    49321 gttcagtcgc cacacctcgg gccagcgcca gggctcctgc aggaaacgcc cggagatgcc
    49381 ccacagggtg tcgccgcgtt ccacggtgta gctgtcgggg gcgtcggcgg cgaggcggac
    49441 gctggactgc gcgtgcgcac ccacgccgag gaggctcgcg aaggcgacga gcagagggaa
    49501 tataattcgc ttcattggac gcttccgatc gggaccttgc gcgccgggtc cgacccggaa
    49561 cgcacgctgc gcgccggggt cgaagcaact gaacgcgtgc tgtgcacgcc ctgcatcccc
    49621 gccgcggata ttccggctaa atacacgccg aagtgtgtga aaacgcttga aattctgcac
    49681 tcaaaggctt aacccagcaa ggtattcatg gctctcctac ccatcctccg ctaccccgat
    49741 ccccgcctgc acacggtcgc gacgccggtc gcccgtgtgg atgacgaagt ccgcaagctg
    49801 atcgccgaca tggccgagac catgtacgag gcgcccggca tcgggctcgc cgccacgcag
    49861 gtcgacgtgc ataagcgcat cgtcgtcatc gatgtctccg aggacaagtc cggcctgatg
    49921 gcgctgatca accccgagat cctcgagcgc tcgggcgaac aggtgtgcga ggaaggctgc
    49981 ctgtcggtac ccggaatcta cgagaaggtg tcgcgcgccg agcgtgtgaa agttcgcgcc
    50041 ctgaacgaaa agggcgaacc cttcgagttc gaggccgacg gcctgctcgc ggtgtgcgtg
    50101 cagcacgaga tcgaccacct cgacggcaag gtcttcgtcg aatacctgtc gcagctcaag
    50161 ctcggccgca tcaagtccaa gctggccaag aaggcccgca tcaccgcgtg atggccgtca
    50221 ccgcaaccgg gaccggcggc ctgagcgtcg ccttcgccgg cacccccgaa ttcgccgcgc
    50281 aggcgctcga cgccatcctg aaggccggct acgcggttcc gctcgtgctc acccagcccg
    50341 accgcccggc cggccgcggc atgaagctca gcccgagcgc ggtcaagcag ctcgcacttg
    50401 ctcacggcat cgaggtcgac cagcccgaga agctgcgcac cgacgcgcag cgcgcccgcc
    50461 tcgcagactg tgcgcccgac gtgctggtgg tcgccgccta cggcctcatc ctgcccaagg
    50521 cggtgctcga gctgccgcgc ctgggctgca tcaacatcca cgcctcgctg ctgccgcgct
    50581 ggcgcggggc ggcgccgatc caccgcgcga tcgaggccgg cgacgccgag accggcatca
    50641 ccatcatgca gatggacgaa ggcctcgaca ccggcccgat gctgctgcga cgcgcgctgc
    50701 cgatcgccgc ggacgacacc accgccagcc tgcacgaccg cctcgccgcg ctcggcggcg
    50761 actgcatcgt cgaggcgctg gcggccttgc agtgcgggca actttcaccc acgccgcagc
    50821 cggccgaggg cgtcacctac gcggccaaga tcggccgcgc cgaggccgac atcgactgga
    50881 gccggccggc gttggagatc gagcgcgcga tgcgcgcctt cgaccccttc ccgggcgccg
    50941 tgtccacctt gcacgacacc gcggtcaagt gctggaaggc gcaggtcgtc gcgggcgagg
    51001 gcgagcccgg ccgggtgctc gcggtcgatg cggatggcat cgtcgtggcc tgcgggcgcg
    51061 atgcgctgcg ttgcacggtg ttacagcgcc cgggcagcaa gcgcctgccc gcgggggaat
    51121 tcctgcgcgg tttcccggtc tctgtgggcg aacgcttcgc gtccctggcg tgagcacgca
    51181 gcgcgtaggc gacggccttg aaggcggtcg cctacgcccc gagctacact gacgaatcaa
    51241 tctcttgcag gaaggatccc gcaatgttcg gaaactggat caagaccacc atcctgatgg
    51301 ccggcatcgt cgccctgttc ggcgcgatgg gtgcggccat cggcggtcag cagggcatgc
    51361 tgatcgcgct cgtgatgggc ggtgcgatga acgtctgggc ctactggttc tcggacaaga
    51421 tggtgctgaa gatgtacaag gcgcgcgagg tcgatgccgc ctcctcgccc tacctgtaca
    51481 acatggtcgc cgagctcgcg cgccgtgccg agctgcccat gcccaaggtg tacatcatcg
    51541 acgaggccca gcccaacgcc ttcgccaccg gccgcaaccc cgacaacgcc gcggtcgctg
    51601 ccaccaccgg catcatccgc atgctctccg agcgcgagct gcgcggcgtg atggcgcatg
    51661 agctggcgca cgtgaagaac cgcgacatcc tgatctcgac catctcggcg acgatcgccg
    51721 gcgcgatctc gatgctggcc aacttcggca tgttcttcgg cggccgcgac ggcgaggagc
    51781 gccccaaccc gatcgtgtcg atcgccatga tgatccttgc cccgctcgcc ggcatgctga
    51841 tccagatggc gatcagccgc acccgcgagt tcggcgccga ccgcggcggc gcggagatct
    51901 ccggcgaccc cgacgcgctc gccagcgcgc tcggcaagat cgacgcctac gcgcgcggca
    51961 tcccgatgca caccgccgag cagcaccccg agaccgcgca gatgatgatc atgaacccgc
    52021 tctcgggtgg cggtctgcgc gggctgttct ccacccaccc ctccacgcag gagcgcatcg
    52081 cccgcctgca ggccatgcgc tgagcgcggc cgaggctcag tccgaggacg cgaaggcgct
    52141 gcggatcagg gcgagcagct cgcccggccg caccgcctcg ccgaaggcgc cggcgcgcag
    52201 cagggtttcg cgccgcgccg cccgaagtgc gggcgcgaac tcggcgtgat agaagatcac
    52261 cggcggccgc cgcgggcgcg cggcgagcac gccgagcagc ttgagtccgg cgctcgccgc
    52321 gccgtcgagc ggttccggac ggtcccagtc cgacaccacc agatcgaatc cgtcctcgtc
    52381 cgcatcgagg cgctccagcg cctccgcagt gctgtgcacg ctcaccacct cgacctgcag
    52441 ctttgccagc gccgccagtt cgtggcgatt gttgtccggc tggtcgtcca cccagagcac
    52501 gcgcttctgc tcgggcatgt cgatcagcgc cgcggccagg ccctccgcct cgccgctggc
    52561 gatgccctcc acacccttga tgcgcgccgc gaacgcgagc tcgtcggcga acgcgccgat
    52621 ggcgcgctgg agcagggcgt cggtgcgggc gtcctccgcg gcggccatct tcagagcggg
    52681 gcgtgccatc tccggcgagt gcatcgcttc ctcgggcagc ggcgcgctcg cgaccgctgt
    52741 gccgagatcg ctcgagcgtg gggcggaggg tgccgacggc gggggaggcg ccgggggcgg
    52801 cgcgctcgcc cagcgctggc ggatggcctc gaccgcacgc cggatgccct tggcgacgtc
    52861 ggtccaggcc tcgtcgcggt tgggccacga ggtcaccggg cgcaggtcgg tgggcaggcc
    52921 ctgcaggtgg gcgaagggcg cgtcctcgat atcgaccgcg cgtagcagca ccgggatcac
    52981 gctggcgtcg ccgcgccgag cgcgctcgat tgcggtggcg agctccttgc cccagatgta
    53041 gtccgagttg aggaagtcca tgctcaccag cagcaggatc aggtccgccg tgctgagctc
    53101 cctgtcgatc gcctcgtccc attgctgccc tggcacgatg ccgcgatcgt gccagggtcg
    53161 gatgacgccc ttgcgccgca gcagcgcgag atggccgtcg agttcgtcgc gcagcttctc
    53221 gtcctcgtgg gcgtagctgt agaagagatc caccggttcc gtgtccatcg tggcgctccc
    53281 tcggcttgtg gtccgttctt caacatagtc caggccggcg gcgccgtcag cgtgcctgcg
    53341 gcggctggcc tctcaggccg cctcgcgctg ggcgaagaag ccggcgcccg cgccttcgcc
    53401 gtcgagcacg gccgcgggcg gccctgccgc gaccacccgc ccgctgtgca tgaaccagat
    53461 cgcgtccatc tcgcgcgcga ggcgctcgtc ctgggtgacc agcagcaccg tggcgccgat
    53521 gttgcgcagc agccggcgta gcgcgtggcg gccggccggg tcgagcaggc cctcgctcgc
    53581 gtcgatcagc agcagccgcg gtgcggcgag cgtggcgcgc gccagcagca ggcggctgcg
    53641 ttcgccggag gacaagtcgc ggccgttctc ggctacccgt ccgtcgagcc cgccgagacg
    53701 tgcaatcgtc ccgccgaggc cgaaatcgcg ggcgacggcc agcagacgct cgtcgcacgg
    53761 gcgaggcgcc agccccaggc tgagcgcgcg ccgcaggctg ccggccagga tgggcgattg
    53821 cgggccgaca tgggcgaaca tccgtcggcg ctgggcgagc ggaaggtcgg tgggcgcgat
    53881 gccgtcgatg cggactcgac cgcgcgcggg ccggtcgagc ccggcggcga ggttcagcaa
    53941 ggtcgtcttg ccggcgccgc tggcgccgac cacggcgatg cgctggccgg gttcggcgca
    54001 tgcgtcgaag cggcgcccgg cctcggtaag tccgacccgc tcgaagctca gcgccggcgg
    54061 tgcattgccg aactgcggcg ggacgctggc cgcgcgccgc ttcaggccgg gtgtggcgag
    54121 cagccgctcg gccttgcggc gtgccagctg ccaggcgcgg tggcggtccc ataccatccc
    54181 gagttcgcgc agcggctgga tcatcagcgc cagcgtggcc aggcccgccg cggtggtggc
    54241 tgcgggcagg ccgtgctgca gcgcggtcag cagcagcgcg gcggcggcgg ctccggagat
    54301 ggcgtccggt aacgcgcgca gcagcgcgct gcggcgcatg cgggcgagcg cggcggcgag
    54361 cagccgcgcc gtgttgcgct cgaggcgggc aagctcctga ccggagcggc cgatcacatg
    54421 cagctgtggc gcgtgcgcca cgcgctcgct catgtcggcg gcgatgcgcg cacggcgacg
    54481 gcgcaggcgg tcatgcgcgg ggccgagccc gaccccggcg atcgccatca gggcgagccc
    54541 ggcgagcagc ggcgcggcca ccgccaggcc gaagccgggc gctaggcaga acagcacgct
    54601 ggtcgacacc ggcagcacga tgccggcgga gatcaggcgc gcgatgccgt ggctgaccca
    54661 gccgcgcacc gctgcgaggt cgcccacgaa gcgcagtgcg agcgcgcccg tgcgccgctt
    54721 cgccagggcc ggggcggcga agcgcgacag gtggcgatac agcgtcgcgc gcacgctggc
    54781 cgcgtaggcc tggcccacgc gctcggcctg gatgcgctcg agcaccttga ggagcgcgat
    54841 ggcgatgccg gcccccgcga tgccgcccag cgcggcccag ggcacggcgc cgtcagccgc
    54901 gtgcagcgcg gcgaacaccg cgcgcatcgc caccgcggcc caggcggcgg cgcaggcctg
    54961 gccgagcgcg agcaccgcga tcaggccgat gcgtgcgccg cggccgtcgg cggcgatgcg
    55021 gggcagcggg ctcaccggcc gaccctccct gcgctcacgc cgccgccttg agggcgggtg
    55081 cgcgcaggcc ggcgagcagc gcgctggcgt gggccgggtc gagcagctcg tcgcgaccga
    55141 gcacgcgcag gccggtggcg gcctcggcct cctgcgcgcc cagcggcgac aggctcaggg
    55201 tgccggtgag cgcgaaggcc tcgaggccga tcgcgttcag caccgcgcag ccgcccaccg
    55261 cggcgagcgc atccggcgcg gcgaacatca gcccggcaaa gtgatcgcgc accaccgggc
    55321 ggcgcagcag cgcggcggtc tcctgctgca gcacgccgtc ggccagttcc accacggcga
    55381 tctcgcaacc tgccgcagct gcgtgcgcga gcaaggtgtc cagtccggcc tcgatgcgct
    55441 cgagcggctc gttgtaggtc gacaccatgc cgacatcggt gaagtcgccg acgaagcgcg
    55501 cgcccgaatc gacgaagctg ttgtagtcgc cgaaggcgcc ggtgccggtg gccttgatcg
    55561 ccgcgacctc gaagcccgcg cgctgcaggc cgtgggcgag gctggccgag gcggtggtct
    55621 tgcccgagtt catcgaggcg ccgacgacgc cgatcacggt catgccggtg ggcgcctgca
    55681 gcggcggcag ggcatggtcg ccgacgttga tgaccttgcc ggcagcatcg gcgagcaggc
    55741 cgagcggcgc cacccgggtc ggggccgcga ccttggcgtt gcgttcgcgc atgcgcccga
    55801 gcacgccacc cgcggcgagg atgtcgacct cgtcggcgtc gagctcggcg aggccctcga
    55861 actggtcggg cgcatagcgg gcgccgcagg ccatgacgac gaggtcgccg gtgtacaggt
    55921 cggcgggccg gccgctggcg agctgcaggc gcttctggaa gccgatgcgc acgatgcggc
    55981 ccagcaccag gtcacccggg cgggcctggg cgaggtcggc gagcaactgg ctggcgcggt
    56041 cctggcggac gcggcgggtg gagaaggccc atttggcctg ggcggcgagc gcgagcgggc
    56101 tcacggcgat ggcggtgcgg gcggtcgggt tcggggcggg ggacatgtgc gttctcctgg
    56161 gcgtgcggcg atgggttcgg gggtggtgag gtcgggcgct caggcggcga gcgcagtggt
    56221 gcaggcgtcc agcgggacgg gtggggcgaa gacgtgatcg accagcccgc cgtcgcggac
    56281 gcagtcgatg aagcggtggc cgcagtcggc cagcgtgtgc aggcggaagc gcgcttcgag
    56341 cccgcgcgcc cgggcggctt gggtgagcgc acgggtccag gtgcgtgcgc gggtgaggcg
    56401 gtcgcggccc tggcggcggt cgagctcggg ggtgctgcgc gtggtctcgt ccgggaggtt
    56461 gtcgagcgtg ccgacgagta cgctgaccgg cagttgcagg aagcggtcga gcgccgcgcc
    56521 gaacttcggt ccccaggcct ggcgcccgga ttcggcgccg aggccgtagg gaaagacgct
    56581 gtggcggtcg ggcagggtgt accagccggc tgcggcggct atcaggtgat cgatgcgatg
    56641 cgggtacagc atggcgaagc ggtgggcgaa ctgggcgccg ccggagaagc cgaagagcgt
    56701 gaatgggcgc ttgccgacca ggccttcgag ggcgagctcg tcgagcaggg cgatcagggc
    56761 gaggtcggcg cgcctgcgct gtaccacgcg ctggtagccg gtccaccccg cctcgtcgaa
    56821 caccggcgcg atgacgacgc ggccctcggc ggcagcgcgg gcggcgaagc tcctcgccat
    56881 ctcctcggcg ccgcgctgaa tgccgtggat ggcgaccagt gcaggcgtgt cggcgcggcg
    56941 ctggtgcggg atcgcgagcc agcacgccag gccgttgcgg ccatgggcgc ggcgccagac
    57001 gatgtggaag ccgtgcaggg tgtcgtgtgc ggggggcagg gactgcttgg gcaggttctt
    57061 cacgatcttt ctccgggggt tgtggggccg atccgaccct ctcggtactg acaacgcgcg
    57121 ccttgcgggt ttattccgcg caggctggaa aaaattctca gcgccgagca ggcgcgtccg
    57181 cctgacgcag cagcgtggcg tagatctcgg cgctatggcg gccggtgacg ggcaggcgat
    57241 gggcggcctg gaagcgcatc agtgcgcgtg cgctctgctc gccccacacc ccgtcggcgg
    57301 cgccggcggg gtggccggca cgcgccagcg cctgctgcac ggcgcggtgg cgatcgtcgg
    57361 gcagcatgcg gccgtaggcc tgcacgctgg ctgcgtagct ggcgggcgag gccgagctga
    57421 gctcgatgca gggggcgtag tcgacgtcga aggcacgcgc gacgtgcacc atgaccgcgg
    57481 cctcggcgat gcggcgctgg gcgaactgcg ggccgtcgtt gctgcgcttg ccgagctcga
    57541 tgccgaaggt gttgcggccg tcctggatgc gcagcccgaa gctcgcgtcg gccgcgttga
    57601 ccgcgacgct gatcgcgctc gcatgcagca cgtggccgcc acgcgaggac atgaagtcgc
    57661 cggcgatgag gtcggtgcgg cgctcgaagc cgaagccgag gtcgaacagc ccggtgccgg
    57721 tgcgacggcg cccgctggca tcggcgccgc cgcggccgac gtcggcgtcg tcctgcgtcc
    57781 acgcgccttc gagcacgatg tggttgccac gcgggcgggt gcggtcggcg tcggccgagc
    57841 gcaccttgtc cgtgcccagg cggtcgatcg cggtgtgcag ccaccaggcg ccgccgctgc
    57901 tcaggcgacg ttcgtcgaac ctgcgtggca ccgtggtgtc gggcacgtcg tccacgaaca
    57961 cggtgagcac gggcttgccg ctgcggtcga tcagctcgcc aaggcaggac agggcgagcg
    58021 agtgctcggt catgaccggg ttgaccgtgc tccggtagtc gctggcctgg tcattgacga
    58081 gggtggcgca gccgccgagc ccgaacaggg cggacgcggc gatgccgacg gcggggatgg
    58141 gggtcttcat gtcggaactc ctggtggtag cgagtcaggg cggtgccctg cctgttccga
    58201 caacgtggct gcagccggtt tattcccggc cgcggcaaaa aattcagtcc gcgttccagc
    58261 cgcgcgtgat cagggcgcgt tcgcgctcgg cgtcgagggg ggcgccgtcc acgttttcgc
    58321 cgagaaaggc gtcggcggct tcgtgcaggc ggtcgctggc ggtgccgtag ccgtttgggt
    58381 cgccttcgcc gccggcgctg aaggcgagct gccagtttgc gtcggccgcg ggtgtgcggc
    58441 aggcgatgcc gatctgctgg ccgcccccgg cgccgctcgt gctgcccagg gtgtattcgc
    58501 ggcagaagcc gccttcacgc gccgggaagc tggccctgat ctccaggcgt tgtccgccgg
    58561 cgtccagcac caccccgctc ggcgccgcct gcagcgccat ggccagcgcg gggtcgcgga
    58621 tcgggtcgcc gacgcgggcg agcggcgcgg cgagttcggt cgggggcagc aggtagtggc
    58681 cgatcagcgc gccgagcgcc agcgtgacca ccgaggcgaa ggccgcggcg gcgccgaaac
    58741 caccgccgag ccaggccgcc aggcgtgcgc ccaggccggg ggtgctcggg cgggtggcgc
    58801 ctgggcgact gccagcgctg ctcggggtga gggcggggcg tccggaggcg ggctgcgcgg
    58861 ctgcagcgtc ggctggccgc gccggggcgc gcgccaggcc ggcgtcggcg gccggagtcg
    58921 ccgtgcgggc gccctcctcg gcgcctggca gcggcgcgct catgattgcc gcgatcagct
    58981 gcggtggcac cgcctcctcg agcttggcgt cgaaggcctg gcgcgccagc tcgccggtct
    59041 cggccagcac ctgcaggcgg gcgcgcagcg cggggctggc ggccagcgcg tcctcgaccg
    59101 tctcgtacgc agcgtcgtcc tcgagctggg cgtcgaggta ggcgatcagg gtgtcgtcgt
    59161 cgatgttcat cagcgcgctc cgtccggtgc gccgccgatg gcgtccgcca ggcgggcgcg
    59221 ggcgcgcgcc agccggctca tcaccgtgcc catcggcacg ccgagcgccg ccgcggtttc
    59281 cttgtacgac aggccatcca ccgtgatcat catcagcacc acccgctgtt cctccggcaa
    59341 ctcgccgatc acccggcgca ccatgcgcgc atcgctgcgc gcttccacca cccggcgccc
    59401 gtcctcgccg gcgatcgcct ccagcgcgtc gctgtcggcc tcggtctgct ggcgctggcg
    59461 gctgcggtaa tcgtccaccc aggtcgtctg caggatgcgg aacatccagc tcgccaggct
    59521 ggtgtcgggc tgccactggt gccagcgctc gatcgccttc aggcagccgg cctgcaccag
    59581 atcgtcggcg acgtgcgcgt cgccggtgag accgaaggcg aagcgccgca ggcggggcag
    59641 caggctgaca agttcggcgc gtgggtcggt ggccgacatg ggctttcctt gtatcgacaa
    59701 cgtcgggcgg agggttttat tccgctccgg gcgaggaata ttcccgcgct cgcgacgttg
    59761 tcgtgatgag tggcagcgcc tcgctggcag acgacgcgag cggcatggag gcggcgatct
    59821 tagcactgcg gtggaaccgg ctcgtcatgc acccactcag accggcgacg acacctcgcg
    59881 tgcgcgtcac gtgccggagg tgtcgcccat ccatgccccg cagtcctcga ggccgaaaca
    59941 acgatgaata tccccgtgtc cttcctccct gcccgctgct gccccgcctc gctgcgtggc
    60001 agtgcgcgtg cgctcgcgct gctgctggcg cttcatgccg cagcatttgc cgaattgccg
    60061 ctgtggaacg gcctcggctt cgccggtatc ggcgcccatg cggacgacgg cgacgggggg
    60121 gatggcgacg gcggtggcga tggtggaggg ggcggcggcg cgggcggtgg ggatggtggc
    60181 ggcggcgggg gcgaggcggc ggccgactac gagccgctgg aagatccctt gccgatcgcc
    60241 ggcgagacct tcatcgccga cgagctgctg ctgctctcgc ccacccaggc ggcattgaac
    60301 cgcgccaccg ccctcggcct gcgcgtgatc gatcgcgtgc aggcgcgcca gctcggcgtc
    60361 agcttcgccc gcctgcgcct gccgccgggg ctggacgccc gcagcgcgcg cgagatcctg
    60421 tccgagcgtg gtccgggcaa attcgatctg caccacctgt acaagatcgc ccaggccgca
    60481 cccgccgcgc gttgcgaggg gcctggctgt gccgcgcgcg agctgatcgg ctggccggcg
    60541 gacagtcgcg cgtgcgggcg cggtcaggcg atcggcatcg tcgacaccgc ggtcgatgct
    60601 gcgcatccgg cgctggtggg cgcggatctg cttcgccagg ccttcgtcac cgatggaaag
    60661 gaggccgccc cggccgacca tggcacggca gtcgccgccc tgctcgtcgg tcagtccgat
    60721 tcggtggtgc cggggctggt gccgcgtgcg cgggtgttcg ccgccgcgcc cttccacacc
    60781 ctgccctcgg gcaatgccac ggcggacacc gcaggcctgg tcaaaagcct ggactggctg
    60841 gtcgggcagg gcgtggcggt gatcggcatg agcctcgccg gcccggacaa cgcggtgctg
    60901 cgcgaggcgg tgcggcgggt ggaggcgcgc ggcatcgtcg tggtggccgc ggccggcaac
    60961 ggcgggcgca acgccccacc tgcctacccg gctgcgcacg agcgcgtgct cggcgtcact
    61021 gcggtttccg ccgatcgccg cgtgtactgg cgcgccaacc agggcgacta catcgactac
    61081 gccctgcccg gcgtcaacgt gtggaccgcc gatccggcgg gtggcgggcg ggcgcgcagc
    61141 ggcacgtcct acgccgtgcc ctacatggtg gcgctcgcgt cgcagaccct ggcgcagcgc
    61201 gtggccagcc gcgacgttct gctcgacggg cggcttggcg ggctcgccga cctcggcgat
    61261 ccgggccgcg atccggtgtt cggctacggc aagccgcgtt ttgatcgcga ctgccgctga
    61321 ttcgccgcag gcgctccggc tgcgatcgtg accgccgcgg tctggttgcg gatgtgccgg
    61381 tcaccatctg cggacggtgc gcggttctgc acgtgacgca tgaacggcgt cccgctggct
    61441 gccgtgaccg cgatcattcg ctcgcgaggc gggcaagcac cgcttcgatg cgcgctggtg
    61501 tcgccgcctt gcccggcagc gcggccgaca gcatcacctc gcgctggcgc cggtccgcga
    61561 accaggtgcg gcgcacgtag tggccgagcg agggcgcgta gtcccaggtg atggtctgca
    61621 gcgggagcgg gaagttcggc gcaaaggcgc tgcagcgcac gtgccaggtg gcgaagtccc
    61681 cggccggcac gaagctcacg cgcgcatcga ccacctcgca gtcccagcgc cgccggacct
    61741 cgctcgcatg gccggtctcg gcccaggtcg tgcgccgggt ctccccgaag ctgacgcgct
    61801 tgcccgccgc cagcggccac agggcagaag gatcgccgtc gatcgtgctg tccacgcggt
    61861 agcccggatg ctcggcggac agcgccggcg cgaagaaatc gcgcgggctg tgcaggctgc
    61921 ggccgtcggg cagcgtccat gtcagcgtct gcgcgctggt ggcggccacg cgggtgaccg
    61981 tgctgcggcc gaacacgaag gtgtcgccgc gctgaagcgt cggtcttgcg gccggcgaca
    62041 gctcgatgcg ctgcgggcgg gtgtcgagcg cggcgcgggt ctcgtccagc aaggtgtcgc
    62101 catggaaggg gaccgccggc agctgcgcgc aagcccccgc tgcaagggct gcgcaggccg
    62161 tgagggtccg ggtgcggcag gtcatcggcg tgctcctggt gatgcagtgc gggtgtgctt
    62221 cgagaccggc gcgggccagg caggttccgc cacgcccgcc ggcgccggct tggtgtaggc
    62281 tgtcggtccc ggcagccggc gacgcacgta cgtgccggcg caaccctcac ctgaaggaga
    62341 tcgacatgag caaagtcacc cttggcggca acccgatcga catcgcgggc cgtgtcccgc
    62401 aggccggcga ggccgcgccc gcgttcaagc ttaccggcgc cgacctggcc gacgtgggcc
    62461 tcgaggcctt cgcgggcaag cgcaaggtac tgaacatcgt ccccagcctg gacaccccgg
    62521 tgtgcgccac ctcgacccgc aagttcaacg ccgaggccgc cggcctggcc gacaccgtgg
    62581 tgctggtcgt gtccgccgac ctgcccttcg ccgccaagcg gttctgcgag accgagggtc
    62641 tgcagaacgt gcacacgctg tcgaccttcc gcaacccgaa gttcgcgcag gactacggcg
    62701 tcgcgatcac ctccggtccg ctcgccggcg tgaccgcgcg cgcggtcgtg gtcgtggatg
    62761 gcaacgacaa ggtggtgtat tcgcagctcg tgcccgagat caaggaagag cccgactacg
    62821 ccgccgcact cgccgccctg aagtaatctc cgcagctgcg cgggcgtcgc cgccgtgcgc
    62881 ggcggcgctc agcgtctcga cgcgttcggc ccagccgcgg ccgggcgctg cggctcgtcg
    62941 aagcggctgt cgtcctcgag cgggaacaca cccagcccct gggtggccag gcgcaccgtg
    63001 gtcggcccgc ggtcctgcga cagcttgaag agctgctcgc ccatgcgcac gatgcagccc
    63061 tcgaacatct cgcgatccgc attcacccgc gcctcgcggg taagcgcgag gcggtgctgc
    63121 aggtcctcct cctcgccgcg caggatctcg atctcgcccg acagcgcgtt cgcggtctgc
    63181 tcggcgcgtc ccaccatctc gggcgtcacg cggtcgggat ggcggtcggc gaaggtgagc
    63241 atcttgccga tctcgagcag gcggttctcc agcgcgtcgc gcgcctcggc cttctcctgg
    63301 atggcgtatt ccagcccggt atccatgccg atctcgagct cggtgcggat gcggctgttc
    63361 gcgccgatcg tgcgcgcgtg gatggacagg ctggcacggc aatgcccgcc gacgatctgg
    63421 ccgcgcaggc gtttgccgac gcggatgtgg ttgcgcgcct cgagctggca ctgcatggcg
    63481 acgtcgtcga tgaagatcga gtcgcccgcg ctgatgcgcg cctgctgcgc gtaggtggcg
    63541 cagaagctgc cctcgcagcg gagcgcgtgc gtgctgtagt ccttgccggc ggtcttgccg
    63601 cccagcccgc cgagcacgcc gcccttgacc acgatgctgc cgcccgcctc cagggtggcc
    63661 ggctcgacca cgccgcccac ctcgatgtcg ccggtggcgc gcaccgtcat gccggcttgc
    63721 acgtcgttgc ggatgcgcac gctgccgtcg aagtcgatgt tgccggtggc gaggttgacc
    63781 gcatccacgg tgaagatcgg ctccaccatc gcgccgttgc gcacccgcac cggctggccg
    63841 tcgcaggcgg ccacgagcag ctcgggatct tcgggcgagg tcgtggtgcc gcgcaggccg
    63901 ggcgcgaagc gcaggtcgcg cccgcgccgc gccatgatcg gccgcccgta cacattgacg
    63961 ccgtccaccc cgggctgcgg cgggtggcgc cgcatcagcg catcgccggc atgcacgacg
    64021 aggatctcgc cgaggtcgcg gtagtcggtg cggccgcagg ggcgcacgct cggcacgcgc
    64081 tcgcgcgtct cggggagcag gtattccagc cagccgtcct tgcccggctc cggctcgcgg
    64141 ccgcgcgcga tggcgagctc gtcggcctgg ccgctggcga tggcgcggtt gatctcgtcc
    64201 agcagcaggc cctcgacgat gccgcgcgat tcgatcaggg ccagcagttc ggtcttgctc
    64261 gccggcctgc cgcccttggg cggcacgatg ctcaggcgcg cgaccaggcc gtcgagcgag
    64321 acgccgatct gcatcgaggc atccacgcac tgcgcgatct cgaccgcttc caccgactcg
    64381 gccgcgttgt actgggcgat caggcggcgg atcgggtccg ggcggatctg cagctccgcg
    64441 tagcccgcgg cctcgagccg ccggcgcagc cacaaggcgt cgatgcgcgg aaaacgcggg
    64501 tcatgggcga tgctcacgct caatgtgcgc gtgagctcgt cgaacgacgc ctccagttcc
    64561 gggccttcgg tgggctgctt gtccatgttt ccagtgcgat ccgatcagcg ggggccgcag
    64621 gtgcggccgg gggattgtag ccgcgtgcat cttgttggtg ccaatgggac gaacccgagc
    64681 cgtagttcag gcccgcaacg cgcgcgcgat gaagtgcttc gccacgcgcg ggcgcggcac
    64741 cttgtcctcg aaccaggtgc gcacgtcggt gtcgaggccg atgccgtgca tgtagttgta
    64801 tagcgccttg ttgagcgccc tgcccaggcg gtcgtggtcc accccggtgg ggtcgatgaa
    64861 gccgacgtcg ttcttcgcga agcggatctc gggcagcggc accagggtga cgccgaactc
    64921 ctccgggttc ctgcctaccg gagaatgcac cgtgcatgcg aagcggtgga agaaacccga
    64981 ctggatgcag ccggcctcga agagctggcg cacgtattcg agcgcgtcca cggtgtcgtg
    65041 caccgtctgg gtcgggaagc cgtacatcag gtaggcgtgc accagcacgc cggcctcggt
    65101 gaaggcgtgg gtgacgcgcg cgacctgctc caccgaaaca cccttcttca tcagctgcag
    65161 caggcggtcc gaggccacct ccaggccgcc cgacaccgcg atgcagccgc tgtcggcgag
    65221 gagctggcag agctcggggg tgaaggactt ctcgaagcgg atgttgcccc accacgagat
    65281 cgccaccccg cgccgcagca gctcctcggc gagcgcgcgc agggccttgg gtggcgcggc
    65341 ctcgtcgacg aagtgaaagc ccgtctgtcc ggtctcggcg atgatcgcct cgatgcggtc
    65401 gaccagcagg ctggcggcag cgccgtcgta gcggccgatg tagtccaggc tgatgtcgca
    65461 gaaggtgcac ttcttccagt agcagccgtg ggccacggtg agcttgttcc agcgcccgtc
    65521 cgaccacaac cggtgcatcg ggttgagcat gtcgagcacc gacaggtagc cgtccagcgg
    65581 caggccgttc caggtggggg tgccgacctc ggcgaagggc acgtcgggtt cggcgaggtg
    65641 gatgtagcgc acctggtccg tatccggatc gcgcacgaag gtccgcacca ggcgcgacct
    65701 gccgcgcctg ccctgcaggt gctcgagcag cgccagcagc gggcgctcgc cgtcgtccag
    65761 ggtgacgtag tcgaagtagt cgaacacccg cggctcggcg agctcgcgca gctcggtgtt
    65821 gacgaagccg ccgccgagca cggtgacgat ctccgggtgc gcggccttga tcgcctgcgc
    65881 gatgcggaag gcgccgtaca ccgagccggg gaagggggtg gagacgagga ccagtcgagg
    65941 gcgatgggtg gagagggctt cgagggtcag ctctttcaga tacgcgtcga ccagcgtcgg
    66001 cggggcggcg agcgcggcgg cgagcggctc gaaggtgggc tggctcatcg acagcgactc
    66061 ggcgtagcgc acgaactcga agcgcgcatc gaccgcgtcg cgcaggatgt cggcgagctc
    66121 gttgaggtag agcgtcgcca ggtggcgcgc gcggtcggcc agccccatgg cgccgaaggc
    66181 ccaggcgagc ggatcgccgc cctcggggtc gtcggggtcg acataggcgt cgagggtgtc
    66241 gaagcgcggt ccctcgggca ggaaggtccg gctggcgatg cgatgcgcga tggtcgggtc
    66301 gcggccctgc aggaaggcga tggcggggcc gatggtgtag cggtagcgcg tgaagtggtc
    66361 gaggaagccc tgcaccagcg gcgtgcgctg cttcctcggc agcgcctcgg cgcgcgtgcg
    66421 gatgtcgtcc agcccggcgg gcgagagcag gcgcagcacc agcttgagcg cgaggtcttc
    66481 ctgcaccgca tcgatgccgc gcgagcgcag gaagccggtg aggtaggcgg tggaggggta
    66541 aggcgtgttg agctgcgtca tcggcgggat gacggagagc acgcgcagcg cgccggcggc
    66601 ctgcccggaa gaggcgggcc gcgcggtggt ttcggacgag gtgggcggcg cggtggcgga
    66661 catggcgggt cgattcgggt gggcgcgcga gcatgccgca gccgctactg gaacgccacc
    66721 tcggcgaagc tgcgcagctt gcggctgtgc aggcggtcga cgccctgcgc gcgcagttgc
    66781 tcgagcgcgc ggatgccgat gcgcaggtgc tggtcgacgc gttcgcggta gaacttgtcg
    66841 gccatgcccg gcagcttgat ctcgccgtgc agtggcttgt cgctgacgca cagcagggtg
    66901 ccgtagggca cgcggaagcg gaagccgttg gcggcgatgg tggccgattc catgtccagc
    66961 gccaccgcgc ggctctggct gaagcggcgc tcggggctgg tcgacatgcc gtgcgagggc
    67021 agcagttccc agttgcggtt gtcggtgctg gcgacggtgc cggtgcgcat caggcgcttg
    67081 agctcgtagc ccgacagctg cgtgacctcg gccaccgcgg cctcgagcgc cacctgcacc
    67141 tcggccagcg gcgggatcgg cacccagggc gggagttcct cgtcgagcac gtggtcctcg
    67201 cgcacgtagc cgtgggcgag cacgtagtcg cccaggtgct ggctgttgcg caggccggcg
    67261 cagtgcccga gcatgatcca cgcgtgcggg cgcagcaccg cgatgtggtc ggtgatggtc
    67321 ttggcgttgg ccgggccgac gccgatattg accatggtga tgccggcgtg gtcgccgcgc
    67381 accaggtggt aggccggcat ctgtggcagg cgcggcggcg gggtaccgtc ggcgtcctcg
    67441 gcctggggcg cgagatcgct gcggcgggtg accacgttgc ccggctcgac gaaggcctcg
    67501 tagccgtggc cggaggcggt gtcggccatc agctcgtggc cgaggcggat gaactcgtcg
    67561 atgtagaact gatagttggt gaacagcacg aagttctgga aatgcgccgg ccgcgtgccg
    67621 gtgtagtggc gcagccggtg cagcgagtaa tccacccgcg gcgcggtgaa cagcgacagc
    67681 ggatgcggct cgcccgggcc gggctcgaag gtgccgttgg cgatgccgtc gtccatggcg
    67741 ccgagatcgg gcaggtcgaa gtggtcgcgc agcaggcggc ggcgctcggg gccgaggtgg
    67801 ccctccaggt agtcgtgctc gggcagggcg aaatgcactg gaatcggctg cgtgctgctg
    67861 cccacctgca gcgccacgcc gtggttctcc accagcaggc ggaactgttc gaggtagtag
    67921 tcggcgaaca gctccggccg cgtcagcgtg gtctcgaaca ccccggggcc ggcgacgaag
    67981 ccgtaggaca ggcgcgaatc cgcgcgcacc acggtgtccg tacgcacgcg cagcagcggg
    68041 tagcaggcgc gcacgtggcg gccgacgtcg gcgccgtcga cgtagtgctg caggccgcgg
    68101 cgcagatgat cgaccgcgag gtcgtagatc tcgtgcaccc gggccagcgc cgccgccgga
    68161 tcggcgaagt cctcgacctc gaagtagggg gcgtggccgt tcatcggctg tccggggttc
    68221 aggagcgcgc gagcatgcgc tggaccgcct cgaggtgctc gggctcgttg tggcacatgc
    68281 cctggaaggc ggcgcacagg tcgaggaagt ccttgagctc catgcgctgc gccatcttca
    68341 tcaggcgctt ggtcaggcgc agcgccttcg gcggctgggc ggcgaagcgt gcggccagct
    68401 cgtgcgcgcg cgccagcagt tggtcgggct cgaccacctc gagcacgatg ccgagcgtct
    68461 tcgcctcctc ggcgccgacg atgcggcccg acagcgtgag ctcgaaggcc tgctggtagc
    68521 cgatcaggcg ctgcatgaac caggcgccgc cgtcgccggg gatgatgccg aggttgagga
    68581 aggtctcgcc gaacttggcc cgggtcgacg cgatgcggat gtcggccatg ttggcgaggt
    68641 cgaagccggc gccgatcgcc gggccattga ccgcggcgat gatcggcacc tcgaccgcct
    68701 gcagcgccag cgggatgcgc tggatgccgc gccggtagcg ggtggccacc tcggccacgt
    68761 cgccggcgaa gtcgccgccg cgcgcggcca tgtccttgac attgccgccg gcggagaagg
    68821 ccgcgccttc gccggtgatg acgagcaccg agacctcgtc gcaggtgttc gcccattcgg
    68881 cgacgccgac gatgtcgtcg atcagcgcgg tgccggtgag cgcgttgcgc acgtcgtcac
    68941 gcgcgagggt cagggtggcg acgcggtctt cgaggatgag gcgggcgtcg cggacggcgg
    69001 gcaggttcat cggaggcttc tcctggtggc tggcggatga atcggtgccg cggcggcagc
    69061 gtggtgcgga gcccggcctt cagcgcggat tgcgcagcgg ttcgggcagc ttgagcgagc
    69121 cggcgtcgct gaagcgggtg ccgccgagca gcccgccggc gagccgcccg cgcagggtat
    69181 aggggacctc ggtcttcggt tcgccctcga tgacgccgag cgcctggcgc accaccgcga
    69241 ttgccgacac cgacaccggg atctccacca gcgcctcgcc gaagcgcggc acgctgccct
    69301 tgcggtcgct gacgccggtg gcgaagggct tgccgttgag gtcgagctcg agggcgaggc
    69361 cgtcgaagtc gatcgccgcc tcgttggggt tctgcacccg cagcttcacc gcgaagcgca
    69421 tctccatgcc cgcgcccggc aggggttcga gccccacgac gttgatgcgc accggctcgc
    69481 gctggatcag gctggcgcag ccggcgagca tcaccgccac gagcagcgcg agcagggcgg
    69541 cggtgaagga cgaggcggac gggcggacgg gaatggacat ggtgccggct ccggggcaag
    69601 ggcgcgcgat ctgcagtcgc gctgggcagg ggatgaccgc cattctaacc gcgccatgca
    69661 aggaagctgc tgcagtcggt cggcacgggg caggccgaag gcgcttctgt cttttgaatt
    69721 cgacctgcaa tggggctatg gtgaaagcat ccgtggtggc ggggcgccgg ctgccctcgc
    69781 gccgttgccc gcttcgtcag cacagccttt ctccctggag tcgagcatgc tttccgctcc
    69841 gcccgcgtct tctcgcgtca cgtcggcgtg ctatgccctc gtgccggcca cagcggcgac
    69901 gggcgcggtg ttggcacgct atggcgagct ggcgctcgtc gtggtcgagc gcgtgcccgc
    69961 cgtggcctgg gcgagctgga cggatctcga tccgatccgg gtcaatgggc agccccgcat
    70021 tctgccctcc ggacacttcg accccggggc ggggccgcgc tgcatcctgc gtttcgccgg
    70081 cccggtgctg ccggcgtggc gcgagatgct cgccgcgctc ggctggacag cgcgcttcga
    70141 ctgcccgccc tgcggactgt gtgtcgaggt cggcgccgac ctcgccgccc tgcgtaccgc
    70201 gctccccgcc ctgcgcgcga tcgcacccta cgaggcggag gattgcgcgc gcgccggcgc
    70261 gggcggggtc gccgcactgc ccgcgaccgt cgatgcggtg gctttcagcg aggaggatcg
    70321 cgcacgcctc gaggacgagc tcgccgccgc cggcctgcgg gtggtcgcga gcagccgcta
    70381 caagctgcgg gtgagcggtg atgggggtgc ggtcgggcgg ctgcgcgacg cggtcggggt
    70441 gaagatcgcc gatccgggca ccctcgcgcg cacggcgtcg gcatccttgc ggctcgcgat
    70501 cggtgcgacc gagacctcgg tgggcgacgg cggcggaccc gccgccggag ctggtggcga
    70561 gggcgaactg atcgcgttcg ccgacaccgg cctgggaagc ggcgcgacgg atgcgccgca
    70621 cccggatttc gccgggcggg tgcaggcaat ccacagctgg ccgctcgcgc ccggatggtc
    70681 ggccttcgtg cgcgctccgg gcgcggacga cggcggcgcg gaccgcggca gcggccatgg
    70741 cacccacgtg gcggggctgg ccgcgggcga cggcggcatg agcgccggca ggctggcggg
    70801 cgtggcgccg ggcgcgcgca tcctgatgca ggcgatcgag cagtacgtcg accccttgcc
    70861 ggaatggcgc ggccgcctgc agcccggctt ctatctcgcg gggcggccgc tcgacctgcg
    70921 cgagctgctc gagcaggcgc gcgccgccgg tgcggcgatc cacgccgacg cctggggtgt
    70981 ggaggccgcc ggcgcctata ccgacgacag ctgggagtgc gaccatttcc tgcacgccca
    71041 ccctgggatg ctggtgatcg tcgccgccgg caacgccggc cgcgaccgca accgcgatgg
    71101 agccatcgat gccggcacgc tgtacgcgcc ggcgagcgcg aagaacgtgc tcgccgtcgg
    71161 cgccaccgag gggccggatg ccggtatcgg cctgcgtggc ggctgggcgg cgctcgaccc
    71221 cgagggcacg cgctttcccg atccggtgca gcgtggcgcg cccgtctcgg gcgatgcgga
    71281 gcggctcgcg ctgctgtcga gctgcggccc cacgctcgac gggcgcatca agcccgacct
    71341 gtgcgcgccc ggtaccaacc tcgccgcggc gcgcagcgca gtgagcccgt cgcgcggctg
    71401 gggtctggcg aatccgctgc cctggtacca gtaccttggc ggcacctcga tgtcgaccgg
    71461 agtggtcgcg ggggcggccg cggtgctgcg ccagcgctgg cgtcgggcgc tgggcgaggc
    71521 gccgggtggt gccgcgctca aggccttgct gatccacggc gcgcggccgg tgcatcgacg
    71581 cgacggacag ggtgaggagg accgcgagcg tgcgggcttc ggccggcttt ggctggccgg
    71641 cagcctgccc ggccccgatg gcccggtgtt gctcgaagac cgcgtcggtc tggcgaccgg
    71701 cacatgccgc cgcatcgact gcaagggccc ggggcggctg cgcgcggtgc tgtgctggta
    71761 cgacgcgccg ggcgaagccc tgatcaacga cctcgacctg gtgctgcgcg acgccagtgg
    71821 cagcgtgcac gcctggggca accacctcgc cggggcggtt ggcattgcgg accggcgcaa
    71881 caccgtcgaa tgcatcgacg tgcagctcgg cgagggcgac tggacgctgg aggtgcgcgg
    71941 cgtgaatgtg ccgctcgggc cgcagccctg ggcgctggcg gcgagtcccg gggtcatcgt
    72001 cgcgggcacg cccgcagcgc cggggacctc gacggcgcct gcggagcctc tgccagcgcc
    72061 gcgatggcgg gtcgatctgc cctggacggc ggtgcgcggc gttggggcga aacgcgccat
    72121 cgagctcgag cgcacgctgc ccgggggcat cggtgcattg tgcgccggtg tcccggatgc
    72181 gggcacgctg gccttcctgc ccgcggcctt gcgcgcgcac atccgcagcc tggccgcctt
    72241 cctcggtgcg tcgccgcctt ccgccgcggt gctcgccgtg gaacatccga cccgtgcgct
    72301 gctcgccggc cctcccgagg ccgcttctgc cgccgactgg caggccctgg ccgcagcgct
    72361 ttctccgttg ctcgaggcgc tcgaccgcag cgtcgcccgc gaggtctgcg gcgagcgctt
    72421 gttccgatga accactcaca aggagtgcat catggctgac aacaccgaaa aacccggcaa
    72481 gggcaagccg acccggaccc aggccggcgc catgccggcg tccgccgcgc tgcccgaggg
    72541 cagcatcctc tcggcgggtg cgctgatccc cggcggggga ggcggcgtgc tggccaacga
    72601 ggccgatgtc tccggcgaac tcgccgagct cgcgccgagc ttcggcgaca tcctggcctc
    72661 gatcggccgt ggcgtggccg attcgcagac cgcgctcgat cgtggcctgg tcgacaccgc
    72721 gaccaccttg tcgcagtcga ccatcaccgt ggtcaccgac gtcgtccagg aactcaacga
    72781 cgacggcctg cccgtgccga gcgcgaccca gctcgtgacc gagaacgtgt cgctgatcaa
    72841 cttcgtccgt cccaccgccc accagtggag ccacgtcgcg ctgcgcatgg acatgaccgt
    72901 cggtgcggtc gacaacgagc gcggcatcag cgtcaacagc aagacgaaga gcgcgcgggc
    72961 gaccaacgtc ggcctcttct tcggcttcct cggcatcggc gtgtcgtcgt tcaaggagag
    73021 atcgaccttc cgctccgagg agtcggactt cgaatcgaac tgggccgagg ggcgcgtgtt
    73081 gatggacgca ctgctgcagc cgcgcaacgt cgagggcttc gatccgccag ccgaggtgtc
    73141 gatcgggccg cagatcttca tggcgctcgg cagcgtgcag gagacgctga actcgggcgt
    73201 cgtcaccgca cgcgccaccg acatcgtcat cacggtgcgc aaggccaatg gcgcggtgaa
    73261 tccgagcgtg atgatcgacg tcgaccccgg ccccttcgac ctgtccttcg cgaccgccga
    73321 cggcttcacc ggcaacacca cgaacgcggc cggacagtgc cggatcacgc tgtcgcgcaa
    73381 catccccagc ccgctgttcc agcgtcgcgt tcgcggcacg gtgacggcca cgctgggcca
    73441 gatcgaacgc agcacgacgg tgtcgctctg atcgccgccc gccacaggag aaaccatcat
    73501 gcctgatcta cttccttccc tcccccgtgt gctggcagag gatgccaatg tctccgacga
    73561 actgcgtggt gccggcatcg ccttcggcac gctggtcgag cgcaccggcg cggccgtggc
    73621 cgcgacccag ctgcagctcg acacctcgag cgccgcgact gcctcggcgc tggcagccac
    73681 gctggtcaat gtgatcgcgg tgcgcgagca ggtgttccgc gacgacggca cgctcgacca
    73741 cgtcaccaac catgtgcgcc ccctgccgtt gatcagcttc atcgatccgg tgttctacca
    73801 atggaccagc gtgcgcctgc agggcgagtt ctacgcgcgc gagttcgcgg cgtcgtccga
    73861 gaccacgagc gcgtattcgg gctcgaattt cgggctcttc ggcagcggcg tgtcgatgtt
    73921 cttcggcccc ggcatgctca ccagcgggag cgggtcgggg tcgaccacga ccaccaccga
    73981 tgtatccacc gacgtctcgc tcggtcgcat ccgtgccagt gcgctgctcg agccgcgcga
    74041 cgacgtcggc atccccaagc ccaaccaggt catccgcggg ccgcggctcg cgctcatcca
    74101 gggcgagatc gccgacgtca tggatggcgg cgacctcatc gggcgcacca tgagcgtgct
    74161 gctgcagtac agtcgccgca atggcgcgcc gatcgccggc aaggcgctgt cggtggagag
    74221 ctccggcgtg ccctggcggc acctgggcac cggcgtcacc gatgccgcgg ggcagatcca
    74281 gatcgagctg cggcgcgact tcctcgacga ggatgccgac accacgccgg cgagcttcgt
    74341 gatcaccgcg cgcatcggcc tggtgagcaa ttcggtcacc gtcaccttct gaacggtccg
    74401 gcgcgggggc ggaatgcccg ccgccgcgcc ggcgggagaa cccatggaca aggccaacat
    74461 cggtgccggc gaactcgccg gccagcaggc cgtggagctg ggcgagctgc tcgcgcgcac
    74521 ggtggtctcg gtcgccgcgg cgcaggaggc gctcgaccgc cacgccaccg atcgcctcga
    74581 cgcgatcgag cgtggcgacg aggacgcgcc gcgggtgccg ccgctgtggt acaccttcac
    74641 cgaggtgacg ctcgaggtcg cgctctccgc gtcggtcgag cgcgcgagcg ggagcgtccc
    74701 gccgcgcctc atgtcgcgcc cggtggatcc gcgccaggtc agcctgtacg gctaccaggc
    74761 gtcgagcagc ctgatggtgc ggctgcggct ggcgccacgg caaggcatgc ccgacgtctc
    74821 gccgccgccc gcctgaaccc ccgctttcct cctcacgaac ccgtccatcc gccatgccca
    74881 tcgatcccaa ggacctccgc agcgctgccg gctcgttgct cgacccccgg ctcgtcgaca
    74941 cgatgaacct gaagcccgtc ggcacctcca gcctggtgag cctggaggga aagctgggcg
    75001 tgttcacccc ggtggcggag gacggcagcg gcgccgacaa caccgaggcc gtgatcgcag
    75061 cgctgcgcaa ggagctcgtc cggctcgaga gcgagaacgc cgccttgcgc cgccagctcg
    75121 ccgaggtcga ggcggcgcgc aagcgcagcc cggacgactt cgccagcgcg gtcgcccaca
    75181 ccctggacac gctgcagcac aagctggcgc agaccaccaa cccggtgagc cgcttcgcgg
    75241 tgcgcgaggt cgcgatcgac gcccaggtga cggtggacgt gtcgccgctc gggaccctcg
    75301 agtaccgctt cgtacgcccc gaggacgaca tcgatccgtc caagctgtcg cgcatccgcc
    75361 tcgacctcgt gcccttgccg cgcgaggacg cgggcttgag cgccgggccc gagttcagcc
    75421 cctgggccgg cgtggaggac atcgtcgggg tcggcgagac ctggcgcggt gcgctcaacc
    75481 gccagcagat cttcaccatc gccgacctgc tggtggcggg gtcgcggctc aagtcgagcg
    75541 ccgaactggc tgcgctggtg ggggtggatc ggcagcgcct ggcagagtgg atgggacatg
    75601 ccgagctgct ctcggtgcgc acgatcgatc cgcgcgccgc cgacgtgctg tggacggtcg
    75661 ggatccgctc gctggagacg ctcgccggtg cggccacggg cgaggtcctc gaaaagtaca
    75721 acgccgaggt cgcccgccgc gcgcacaaga gcctggcccc gatcgatgcg gcacaggccg
    75781 ccgcctggat cgaggccgcg aagaagtacc acggccggcc gcgcgagggc ggctgaagcg
    75841 gcctcagtcg cgcacgagcc agtcgagcag gccgtccatc agcgcgtggg tggcggcgaa
    75901 gtgcgcgcca gaccgcccca ggatcgtcgc ctcgtcctgg atccagcgcg ccggcaccag
    75961 ttcgccgcgg cagttgtcga cgatcgcgcg caggctgggt tcggtcatct cgaggtggaa
    76021 ctgcaggccg atcgtgcgcg cgccgagctg gaaggcctgg ttccggcacg ctgcgctcga
    76081 ggcgagcagg tgcgcgcctt gggggaggtc gaaggtctcg ccgtgccagt gcagcacggt
    76141 cgcgtgcgcg gggaagggga agcgtggcgc ggcgccttgc tcgccctcgt cgccctgttc
    76201 cgcgccgctg gcggcgacct cgaaccagcc gatctccttt gccgtgttgc gatagacgcg
    76261 tgcgccgtgc gcgctggcga tcagctgtgc gcccaggcag atgccgagca ccggccggcc
    76321 gcgcgcgacc acgtccgcga tgaagcgctt ctccgcgatc agccagggga attccgcctc
    76381 gtcattgacg ctcatcggcc cgcccatcac cacgagcagc tcgaccgcgg ccgggtcggg
    76441 cagcgccggc gattcccaca ggcgggacgt gccgacgtcc gcgccgcgcg cggcgagcca
    76501 gtcgccgatg tggccagggc cttcgaaggg gacatgctgc aggatgtggg ctttcatggt
    76561 gtgctggggc agtgaggtgg aagggcaata ttctagaagc gcgaacccgg ctggcgcagg
    76621 aactcggctt cctccgggct cgtctcgcgc ccgagcgcgc cattgcggtg cgggaagcgg
    76681 ccgaagcgct cgatgatctc gaggtggcgg cgggcgtagt cgaggtagcc ggcgaaggcc
    76741 gggcgcagca tgggctcgac cgctgcggcg agcgcgtcga accggcgcac cgcctcgcgc
    76801 tggtcggcga gattctcgga gtgctccagc ggcaggtaca ggaagacgcg ctcgatcggc
    76861 cgcagctcgc cgtcgagccc gcgcgcgagc gcatccttgg cccagcgcag cgcgagcacg
    76921 tcgaaggcga aggccgcggc ctcgccgcgc cagatgttgc gcgggaactg gtcggtcagc
    76981 aggatcagcg ccaggcgtcc gcgcagcccg cccagccagg cgtcgaactc cccgaccgcg
    77041 gcgcgcccca ccagcggagc gaagcgtgcg cggatcgcgg catcgacctc gggctgcttc
    77101 ttccaccata gcgccgactg gcgctcgatg atgacgtctt cctcgtcctc gtcggccgcg
    77161 gggccgaacc agaaggcgtg gatcgtggcg ggcgtttcca tgcgcggctc cgggcggacg
    77221 atcggggtgg ggcaagcata gcccagcgcg ttgcgatgcg ggatgcgccg gagcgggcaa
    77281 tggaccgctc tgctgccgcg caccctgccg gcgcggttgg cgcaataatc cggccatgac
    77341 ccgcgaaacc gcctcccccg tcgcgctctc caccctgcg
//
LOCUS       DAOTIN010000003        72345 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_324_length_72345_cov_9.368723, whole genome shotgun sequence.
ACCESSION   DAOTIN010000003 DAOTIN010000000
VERSION     DAOTIN010000003.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 72345)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 72345)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72345
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_324_length_72345_cov_9.368723"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..219
                     /locus_tag="P5537_00795"
     CDS             <1..219
                     /locus_tag="P5537_00795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylesterase"
                     /protein_id="HRV76609.1"
                     /translation="ANRRTPVFAAHGTHDDVVAPELGRQAVELLRQLGIEPEWHDYPL
                     PHSVSLEEIADIGRWLGAILRAPGHHDG"
     gene            complement(251..1243)
                     /locus_tag="P5537_00800"
     CDS             complement(251..1243)
                     /locus_tag="P5537_00800"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76610.1"
                     /translation="MTVSTFPALRSRGRHVSAAALLLAVLGLSGLPAAACEPVLAVED
                     GGRILLWQAPGPAREVVEGGCAAIDAAAERLAYCTRPAADTRQAVQLNVLPLAGGDAQ
                     RVHAGREGDAISEAAWSPDGSRLAFILTDARFRSHLMVVEPGSPARRLASAANAENHQ
                     WWSLGWLADGSAIGVHDMEHYALIAADGGGVRESIPLARMLGVQAEAISSTDRVLPSP
                     RDPTVFAYTLGVPGTARFRQAMHEPNTALFVHDRFLGRGKNLRLSAEHVTVVDAAWAP
                     GGLALYFSGYLDRHVNEDDPFRVYRIERSGQGMRELLRGERVSAGCRAASAGPA"
     gene            complement(1456..1532)
                     /locus_tag="P5537_00805"
     tRNA            complement(1456..1532)
                     /locus_tag="P5537_00805"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1496..1498),aa:Arg,seq:ccg)
     gene            1681..2127
                     /locus_tag="P5537_00810"
     CDS             1681..2127
                     /locus_tag="P5537_00810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="c-type cytochrome"
                     /protein_id="HRV76611.1"
                     /translation="MSNPRTLRPARLAMPVALVAAALLAGCGDQSKIDPETTATLIQP
                     VARVEIQAVTITPGTRTGEQIYKSICAACHDSGAVGAPKTGDAAAWGPRLALGHDGLT
                     ASAIAGKGAMPPRGGGSDLTDTEVSRAVAYLANLAGAGYTEPPVEQ"
     gene            complement(2210..4201)
                     /locus_tag="P5537_00815"
     CDS             complement(2210..4201)
                     /locus_tag="P5537_00815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HRV76612.1"
                     /translation="MSALLNAPQREAIRYLDGPCLVLAGAGSGKTRVITHKIAHLINE
                     CGISANNIAAITFTNKAAKEMQERVAHIMGGRVPGGLTVCTFHALGVRIIRQEAKHCG
                     LKPQFSILDASDTVQIVSDVAGDSDKGIAKQMQWQISSWKNAMITPEEAAQLADNEIA
                     SVAAKLYKEYERTLRAYQAVDFDDLISLPVRLFDEHPEVRERWQNKLRYLLVDEYQDT
                     NRAQYRLLKLLSGVRGAFTAVGDDDQAIYAWRGADVENLKLLQQDYPKLKVIKLEQNY
                     RSSRRILEAANTVIANNEKLFDKRLWSEHGQGEQIVVTNCRDAEHEAEWVATKIVAHK
                     FEHRTRFKDYAILYRGNHQARLIEQQLRNHRIPYVMSGGQSFFDKAEIRDLIAWLRLL
                     VNEDDDLAFIRAITTPRRGIGAATIEALGAYAGHRHSSLFTAVFEEGLTQHLNAKQLQ
                     GVQEFAAYINRLQYRAPREPAAQLLEDLLGAIRYEAWLFEHCDTREAESKWSNVRDFV
                     GWLGRKGEEDGKNLLELTQTIALMSMLDKEDPDFDGVQMATLHASKGLEFPHVFLVGV
                     EEGLLPHQSSVDEDKVDEERRLMYVGITRAQRSLNLTWCERRKSGKEFRPCEPSRFIA
                     EMGGDIRMNDRKTAQPVTKEEGKARLANLMAMFESRDKG"
     gene            complement(4342..4782)
                     /locus_tag="P5537_00820"
     CDS             complement(4342..4782)
                     /locus_tag="P5537_00820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemerythrin domain-containing protein"
                     /protein_id="HRV76613.1"
                     /translation="MTNPPVFTWSDRFLLGHRTIDDTHREFVDCVDALLRASDAEIPA
                     ALDAFARHAEAHFAQEDQWLAAPDFPNGGECHIDEHAKVMASVREVQELVGKGEVAIA
                     RELAQALMDWFPGHADYMDSALATWLVKKSHDGRPLVLRRKEHL"
     gene            4988..5485
                     /locus_tag="P5537_00825"
     CDS             4988..5485
                     /locus_tag="P5537_00825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HRV76614.1"
                     /translation="MKLKIAAAVAVLILAVAGFFVFTQKPAAPDVTFSTLQGQSFRTA
                     DLRGKVVLVNFWATTCTSCIKEMPALKATQERFEARGYRTVAVAMDYDPPAQVAAFVE
                     RSALPFTFVLDRDGSIARGFEGVRLTPTSYVLDRRGQIVQKILGEPDFDKLHGLLEQL
                     LAEPA"
     gene            5506..6153
                     /locus_tag="P5537_00830"
     CDS             5506..6153
                     /locus_tag="P5537_00830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HRV76615.1"
                     /translation="MPMIRATLHAALSASLLLALLPPAHAQRSGNIGGCDIRRGTLCT
                     NLNLNGANLEGVNLANSQFTRSDLSGANLRGATLNEANFSQAEMAGATLDGASMLRTN
                     LRGARLTGASFKEADLRNAILQNADLHDADLSAAKLGGADLTNARAERSRFDGAELTR
                     SNLRAAKLAGASFAGANLQGANFTRAQLSNADLTGANLDQAIFLNAQTDGCKGCP"
     gene            complement(6255..6977)
                     /locus_tag="P5537_00835"
     CDS             complement(6255..6977)
                     /locus_tag="P5537_00835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002925373.1"
                     /note="The SIMPL domain is named for its presence in mouse
                     protein SIMPL (signalling molecule that associates with
                     mouse pelle-like kinase). Bacterial member BP26, from
                     Brucella, was shown to assemble into a channel-like
                     structure, while YggE from E. coli has been associated
                     with resistance to oxidative stress; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIMPL domain-containing protein"
                     /protein_id="HRV76616.1"
                     /translation="MAEGRIGIVPALILAAGIGFAGMQVAGGIERFRMAERTLTVKGL
                     AERDVKSDFAVWTVPFRRAENDFGSVQQALTADRERVVAFLREQGFSDDEIEVRPLQV
                     QDLLAREYGSDRVALRFTGQGQVVVKSARVDLVAAASNRVDPLVEAGVQLGGDGSDGT
                     PRYQLRGFNDIKPILLEEATLSARELASKFAADAGARLGPLRSANQGAIRITDDDDSD
                     MDTSRTIGKRLRVVSTFQFGLE"
     gene            complement(6980..7927)
                     /gene="lipA"
                     /locus_tag="P5537_00840"
     CDS             complement(6980..7927)
                     /gene="lipA"
                     /locus_tag="P5537_00840"
                     /EC_number="2.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016992 - lipoate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009107 - lipoate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl synthase"
                     /protein_id="HRV76617.1"
                     /translation="METPARKQRGADKTARIPIKIVPAERLKKPDWIRIKLGAGMEAE
                     RFNEIKATLRDHKLHTVCEEASCPNIHECFGKGTATFMIMGDICTRRCPFCDVGHGRP
                     EPLNADEPRDLAKTIAAMRLNYVVITSVDRDDLRDGGAQHFVDCIRETRAASPKTRIE
                     VLVPDFRGRMEIALDIFDAAPPDVMNHNLETVPRLYKQARPGSDYAYSLELLKQFKAR
                     HPDVATKSGLMVGLGETDDEILEVMRDLRAHDVEMLTIGQYLQPSGGHLPVLRYVHPD
                     TFKMFETEALKMGFKNAACGPMVRSSYWADQQAHGAGVV"
     gene            complement(7993..8673)
                     /gene="lipB"
                     /locus_tag="P5537_00845"
     CDS             complement(7993..8673)
                     /gene="lipB"
                     /locus_tag="P5537_00845"
                     /EC_number="2.3.1.181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033819 - lipoyl(octanoyl) transferase
                     activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl(octanoyl) transferase LipB"
                     /protein_id="HRV76618.1"
                     /translation="MIVKRLGLVEYAPALEAMRVFTAQRGADTPDELWLLQHPPVYTL
                     GQAGKPEHLLQNPANIPLVHIDRGGQITYHGPGQLVAYLLLDLPRRRLKVRELVNLME
                     QAIIDTLADYGIEAERKDGAPGVYVAGDKIAALGLRVRNGCSYHGLAINVDADLAPFG
                     WINPCGYEGLKTIRMKDFGVDAGVEQVGEVLLGHLQRLLPPPSSDIGETDNAAAASPV
                     AVAARAGS"
     gene            complement(8670..8954)
                     /locus_tag="P5537_00850"
     CDS             complement(8670..8954)
                     /locus_tag="P5537_00850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF493 domain-containing protein"
                     /protein_id="HRV76619.1"
                     /translation="MADQQDAQTRQSLIEYPCDFPIKVMGARVDGFAQAVIEVVLRHA
                     PDFEPAGAEMRPSSKGNYLAVTCTFRAVSQVQVDAMYRELTAHPMVKVVL"
     gene            complement(8992..10119)
                     /locus_tag="P5537_00855"
     CDS             complement(8992..10119)
                     /locus_tag="P5537_00855"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HRV76620.1"
                     /translation="MRFLIAVLVSLFSLSALAQTVPPPALAAKAWALVDHATAQVLAE
                     KDADARIEPASLTKLMTAYITFSKLKEGTLKPDQVVPVSTKAWRMEGSRMFIEPNKPV
                     SVDELIRGVIVQSGNDACVALAETIAGSEEAFAALMNREAQRLGMTNTHFTNSTGLPD
                     PQLYTSARDLALLASAIIRDFPEYYSLYSLKEFTYNGIKQPNRNRLLYMDPSVDGMKT
                     GHTSSAGYCLVSTARRGERRLISVVLGAASDTVRAQESLKLLNFGYQFFETVKLYSAD
                     EALSKFRVWKGKLNELPVGFLNDFALTVPKEAANKIQVSLESRQPLVAPLQRGQEVGT
                     LTVAIDGKPLGQYPVVALQDAEVAGFFGRLWDAIVMFFKSL"
     gene            complement(10228..11361)
                     /locus_tag="P5537_00860"
     CDS             complement(10228..11361)
                     /locus_tag="P5537_00860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septal ring lytic transglycosylase RlpA family
                     protein"
                     /protein_id="HRV76621.1"
                     /translation="MTPVPPLPPAARASGLRARRALAMLGVACAAALLTACGSAPRRE
                     GPVAEAPARAGTPERSPARRGGGYYKDDGPEDEIPDDLDAIPDAEPRDEPLHRYANRP
                     YHVMGQSFVPATAVRAFRQRGHGSWYGRRFHGKPTSSGEPYDMYAMTAAHPTLPIPSY
                     ARVTNLGNGRSVVVRVNDRGPFLRGRVIDLSYAAAHKLGYINSGSAEVEVEQILPGEA
                     PLVAAARPVPPLRARANEGLVPGVGPVIGMKPLAPLPVAQAPLAAPAASPVRPADTAI
                     APPECEEGPACGAAGGFAPPVASASAGIFLQLGAFSSFANAEGFRDTVRSQASNLAER
                     FELFTDGERFRLHAGPYDTVEAARDAAARMGNVLKLKPFVVVR"
     gene            complement(11379..12521)
                     /gene="rodA"
                     /locus_tag="P5537_00865"
     CDS             complement(11379..12521)
                     /gene="rodA"
                     /locus_tag="P5537_00865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HRV76622.1"
                     /translation="MNDNRFNPLALVLGFLRPLDPVLMFVLAALLGYAHVLMQSASPE
                     RLDSQITHIGIALAGMWVLAWLKPQRLLSMAVPLYLLGVVLLVAVELFGEVSKGAQRW
                     LDLGVARIQPSELMKIAMPLMLAWFFQMREGQTRFIDFILAGALLLVPVGLIVIQPDL
                     GTSLLIAASGLYVIYFAGLSWKLLIPLMVALVIGLGSIVAFGDTLCQPEVDWQVLREY
                     QKQRVCTLLDPTRDPLGKGFHIIQSTIAIGSGGLTGKGWMDGTQTHLAFLPERHTDFI
                     FAVLAEEFGLVGALVLLAVYVLLLLRGFHIAANAPTHAARLLAGAITMIFFTYAFVNM
                     GMVSGILPVVGVPLPFISYGGTALVTLCLGIGILMSIQRSRFADKT"
     gene            complement(12518..14563)
                     /gene="mrdA"
                     /locus_tag="P5537_00870"
     CDS             complement(12518..14563)
                     /gene="mrdA"
                     /locus_tag="P5537_00870"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HRV76623.1"
                     /translation="MTEFRAPAAELARFRLRVVVAAVFVLVCFGLLAARFHHLQVKRH
                     DYFLTRAEDNRIALLPVVPHRGTIVDRRGVVLARNYATYTIEITPSQVRNLDATLDEL
                     AGLLPLDARDRRRFRKLYEESRNFESVPLRSRLTDEEVARVVSQRYRLPGVDVKARLL
                     RDYPQGSTASHVIGYIGRVTERDVERIEEAGNAANYRGTLHMGKAGLEQSYEHELHGT
                     TGFEQVEVNAGGRAVRALSHTAATPGNDLELTLDIELQKVAEKAFGDRRGALVAIEPS
                     TGGVLALASMPTYDPNLFVDGISTQDWKALNDSPDHPMLHRAIYSTYPPGSTFKPFMA
                     LAGLETGKRTAKQAMYDVGYFQFGGHRFMDDKIGGHGMVDLHKSIVVSCNTYYYQLAN
                     DLGIEGIAGFMAPFGFGERTGIDLPGEATGVLPSPEWKRNRFKKPEQQRWFAGETISV
                     GIGQGYNAYTPLQLANALAALVNQGKLFRPHVVKYVVDSRTGERRAVEPEPLRQIPLR
                     DAHLKAVLDAMVDVNRTGTGKRAFKGAPYTVGGKTGTAQVFSLRGQRYVEGRVRERLR
                     DHSWFVAYAPAENPRIALAVLVENGGFGAQSAAPIARQVIDYYLLDQRAGAPAAEDEE
                     GAESEEGAESGGDALPASRIVEPALPLEAPPAPVPSRPATPPAAVPAPQPAAARSAR"
     gene            complement(14576..15097)
                     /gene="mreD"
                     /locus_tag="P5537_00875"
     CDS             complement(14576..15097)
                     /gene="mreD"
                     /locus_tag="P5537_00875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HRV76624.1"
                     /translation="MHPTNRSSRILQPVKLWFVYLSLFVALGLEYIPTGRTPGLPDWV
                     ALVLAFWCVREPLAIGMGAGFAFGLLMDVGLGAAMGQHALAYVVLAYLANALARRVLW
                     FPAWQQALHVLPLLLLAQAIMVLVRLLAGAEFPGWSYFLSSLGSALLWAPLSFLLLLP
                     QYQPDERDDNRPI"
     gene            complement(15101..15979)
                     /gene="mreC"
                     /locus_tag="P5537_00880"
     CDS             complement(15101..15979)
                     /gene="mreC"
                     /locus_tag="P5537_00880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002925397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HRV76625.1"
                     /translation="MSLVGHQPPPIFRRGPAPLARLFVFVALCLVLLVADLRFRYLEV
                     LRNALSVVTYPLQMAASTPADVVRNATRYFGTLVDVQLENADLRRLQLDAGERLLRFE
                     QLEQENLHLRELLQMSERVQTKSIAADILYNAPDPFARKVILDRGTQQGVEAGLAVVD
                     ANGVIGQVTRVHPVQSEVTLLTDRNQSIPVSVVRNGVRGVLYGVGRGMLEMRHVLAEV
                     DIQPGDRLVTSGLDGIFVPGLPVATVTRVDRDQDAFARIECEPLAAIERSVQVLVIGR
                     AAYPPPPPPPEPAGER"
     gene            complement(16051..17094)
                     /locus_tag="P5537_00885"
     CDS             complement(16051..17094)
                     /locus_tag="P5537_00885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000902 - cell morphogenesis [Evidence
                     IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HRV76626.1"
                     /translation="MFGFLRSYFSNDLAIDLGTANTLIYVRGKGIVLDEPSVVAIRTE
                     GGPNAKRSIQAVGHSAKQMLGKTPGNITAIRPMKDGVIADFVVTEQMIKQFIKKVHDS
                     RLLSPSPRIIICVPCGSTQVERRAIRDAALAAGASQVFLIEEPMAAAIGAGLPVSDAT
                     GSMVVDIGGGTTEVGVISLGGIVYSGSIRVGGDKFDESIVNYIRRNYGMLIGETTAEK
                     IKKEIGSAFPGSEVREMEVKGRNLAEGIPRSFTISSNEILEALTEPLNQIVSAVKIGL
                     EQTPPELGADIAERGMMLTGGGALVRDLDRLLMEETGLPVVVAEEPLTCVARGCGMAL
                     DKMDKLASIFTSE"
     gene            17265..17552
                     /gene="gatC"
                     /locus_tag="P5537_00890"
     CDS             17265..17552
                     /gene="gatC"
                     /locus_tag="P5537_00890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004376355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HRV76627.1"
                     /translation="MSLSNDQVGHIARLARIAVSASELEATRDKLNGIFGLIEQMQAV
                     DTSGVEPMSHPQELATRLRPDLVTEADRREAFQKVAPQTEAGLYLVPKVIE"
     gene            17638..19110
                     /gene="gatA"
                     /locus_tag="P5537_00895"
     CDS             17638..19110
                     /gene="gatA"
                     /locus_tag="P5537_00895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002925410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HRV76628.1"
                     /translation="MINASLPELRRALDARQISAVELAGLFLDRIDALNPALNAFITV
                     DREGALAAAHTADQRIAAGSAGPLTGIPLAHKDVFCTEGVLTTCGSKMLANFVSPYDA
                     HVVSLLKAAGAVSLGKANMDEFAMGSSNESSYYGAVKNPWNPERIPGGSSGGSAAAVA
                     ARLAPIATGTDTGGSVRQPASYCGITGIKPTYGLVSRYGMIAYASSLDQGGAFGASAE
                     DCALLLSAMTGFDERDSTSLERPTEDYAAALAGPASTRPLEGLTIGLPREFFAEGMAD
                     DVRATIDAAIAQYRALGATTVEVSLPNARLAIPAYYVIAPAECSSNLSRFDGVRYGHR
                     AADYGDLADMYAKSRAEGFGAEVKRRILVGTYVLSHGYYDAYYLQAQRLRRLIAQDFQ
                     AALQHCDLIAGPTTPTTAWALGEKADDPVQMYLSDIYTIAVNLAGLPGLSHPAGFGAD
                     GLPVGLQLIGDYFAESRLLNAAHRFQQATDWHTHRPACAA"
     gene            19107..19643
                     /locus_tag="P5537_00900"
     CDS             19107..19643
                     /locus_tag="P5537_00900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011763907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76629.1"
                     /translation="MNHTRHLCAAAPERFGRRVCGRLGALAAAVLLSACTLPMLPPSD
                     APVSDEVLASPSSAGKRLRPMPWRPLDVRADCRFSDEAGYVTRITLDVAQSKVRTFNA
                     DVEIPRRGSCRFHGPFTQTREKPSVQLRAPDGCTVDIFEQGKDVTVGFANCASRCSRG
                     AFDYLWPIIVDRTNGQCH"
     gene            19676..21148
                     /gene="gatB"
                     /locus_tag="P5537_00905"
     CDS             19676..21148
                     /gene="gatB"
                     /locus_tag="P5537_00905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HRV76630.1"
                     /translation="MSRSDWEVVIGLEVHAQLNTASKIFSGASTAFGAEPNRQASAVD
                     IALPGVLPVLNRGAVERAIRFGLAIGAHVAEKSVFARKNYFYPDLPKGYQISQMDLPV
                     VVGGAITIRVGEGESGYEKTVRLTRAHLEEDAGKSLHEDFHGMTGIDLNRAGTPLLEI
                     VSEPDMRSSAEAVAYARALHALVRWIDICDGNMQEGSFRCDANVSVRRKGAAEFGTRR
                     EIKNLNSFRFLQQAIDYEVQWQIDTLEDGGRVQQATVLFDPDTGETRMMRSKEDAHDY
                     RYFPDPDLLPLMIAPEWKARVQAEMPELPGAMKARFMDAWGLSAYDATTLTASKEVAD
                     FYQATVSATGASLATQLPKLCANWVMGDLAARINKAELDVSASPVSPAQLAGLVARIA
                     DNTISNAIGKKVFEALWNGEGATADEVIERQGLKQVTDTGAIEAMIDEVLAANQKSVE
                     EFRAGKEKAFNALVGQVMKASKGKASPAQVNELLRKKLGA"
     gene            21182..22015
                     /locus_tag="P5537_00910"
     CDS             21182..22015
                     /locus_tag="P5537_00910"
                     /EC_number="2.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II glutamine amidotransferase"
                     /protein_id="HRV76631.1"
                     /translation="MCQLLGMNCNVPTDICFSFAGFRARGGLTDHHRDGWGIAFFEGR
                     GVRVFLDPAPSAHSPVAELVNRYPIRSLNVIAHIRKATQGDIRLENTHPFQRELWGRY
                     WIFAHNGNLKEFAPALSGRFLPVGSTDSELAFCHILDTLAARFPEGKPAPAELHAALR
                     ELALGIGSRGEFNFLLSDGDWLFAHCSSRLCYIVRRAPFAEAHLADEDLTVDFRRLTG
                     PQDRVAVIATTPLTDNELWTQIPPGNLLAFRDGEPVALGETATMAQDYPRRGGDKVGS
                     A"
     gene            22092..22511
                     /locus_tag="P5537_00915"
     CDS             22092..22511
                     /locus_tag="P5537_00915"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HRV76632.1"
                     /translation="MDCPLCALPSELTLWEDERCRVIRVDDAAHPGFCRVVWGEHVAE
                     MTDLSPADRRHLLDVVMATEAALRSLLNPDKINLASFGNMVPHLHWHVIPRYRDDRHF
                     PESVWGVAQREGVAHPAADAVALARAIDGALYPGGPD"
     gene            22524..24143
                     /locus_tag="P5537_00920"
     CDS             22524..24143
                     /locus_tag="P5537_00920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76633.1"
                     /translation="MDYSQPAVCLALLQKLHPTDFRATHASLVRIVNGLLDASPAPNQ
                     HLEVLEAARETLAFVQGEMAHAYAIHPQPAARSQEGGALERVVSLWKAVARSYARIAD
                     SDAREGTLEDQRALLAQRRVFYEGLVLVEYYRAHLELPPGLWHAVHVAYDDAVRNGLA
                     QVRVTDPLNEVWRAQSAQEAYIGTLLVELANPYGRGERELNWVVRWAQRFAPYCALDA
                     DIEGHKPSTYGIDTDGDSGLRPLGLLAHTPSVLRFDGSGLATQIQAVMAQFKRGVTPA
                     SLGLGNDCSASSSARLLLSLYRPWGLAASGRRFPRRRKSGVIDFTGDWLAIGYAIKGE
                     LFQQPVTEQRPRAFRDDMSLLTFGERVATVDGSTSESRRREAQAADLGMECERWELMD
                     QSVGGFRLRRSGDGPRLDHHQLVGIRPPDADQLLIADLSWLMYRNDGTLEVGINVLPG
                     VPRVVGVRRTIARNGSREPFHQAFMLPPSPALKTAGTLVLPPAWFKKDRILDVQDGQE
                     RRQVRLLKVSMRGANFDQCSFEPVEQEFSPA"
     gene            complement(24130..25446)
                     /gene="phoR"
                     /locus_tag="P5537_00925"
     CDS             complement(24130..25446)
                     /gene="phoR"
                     /locus_tag="P5537_00925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006796 - phosphate-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate regulon sensor histidine kinase PhoR"
                     /protein_id="HRV76634.1"
                     /translation="MIRRPLSYLALVIALPLGTLMVLAALAAAYRGSDAALALLAVGL
                     VGWAIMLVRNLRQLVTWARQPVGTPVPQAEGLWGRVFAEVGDRLQRECEVKERLSAEL
                     GRFQQAALAMPDGVIYLAEDDAIEWMNPMAEQHFDLDRRKDLRMALSGLVRQPEFVRY
                     LAAHEYAEPLVMRSLRRRERSLQVQVIAFAGNRRLVLSRDVSQLERLETMRRDFVSNV
                     SHELRTPLTVVGGFLETLIDGIDDFTRDEVVQYLGLASEQSSRMQRLIEELLTLSALE
                     TGAPAPAEERVDVQALVRDVVRDCELLSAGRHEVRLVLEGGGELLGSHKELRSAFSNL
                     ASNAVRYTPAGGHIEIGWRAGGGGGEFWVADDGIGIDAVHIPRLTERFYRVDRGRSRE
                     TGGTGLGLAIVKHVTTRHHGELVIESEPGRGSRFTLRFPPARVRPG"
     gene            complement(25468..26178)
                     /gene="phoB"
                     /locus_tag="P5537_00930"
     CDS             complement(25468..26178)
                     /gene="phoB"
                     /locus_tag="P5537_00930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006796 - phosphate-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate regulon transcriptional regulator
                     PhoB"
                     /protein_id="HRV76635.1"
                     /translation="MPANILLVEDEPAIQELIAANLARAGHHVVRANDAESAQRIVRE
                     ALPDLVLLDWMLPGASGVEFARRLRADERTSDIPIIMLTARGEEQDKVTALEIGADDY
                     VTKPFSPRELVARIKAVLRRRAPQTTEDVVELGGLRLDPATHRVSAGETALALGPTEF
                     RLLHFLMTHPERVHSRAQLLDQVWGDHVFVEERTVDVHIRRLRCALEPSSHDALIQTV
                     RGSGYRFSVHTAQAAAAS"
     gene            complement(26398..27372)
                     /gene="hcrB"
                     /locus_tag="P5537_00935"
     CDS             complement(26398..27372)
                     /gene="hcrB"
                     /locus_tag="P5537_00935"
                     /EC_number="1.1.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybenzoyl-CoA reductase subunit beta"
                     /protein_id="HRV76636.1"
                     /translation="MNILADFRTHRPATLADAVAALDADGAVPLAAGTDLLPNLRRGL
                     GQPEVLVDLGGIDGLGTISTLADGSLRIGAGATLEAVAEHALVRAGWPALSQAAEAVA
                     GPTHRAAATLGGNLCQDTRCIFYNQSEWWRAGNGYCLKYRGDKCHVIVKNDRCYATYH
                     GDVAPALMVLDARAELVGPTGRRSVAVAELFREDGAGHLALNRGELVAAVEVPPADGW
                     TAAYAKARIRDAVDFPLAGVAVALRRDGDRIAGLRVAITGSNSAPLLVPTDELVGGGW
                     DGAAAEALAQLVRKTSNVLKTTVTGVGYRRRVLLALAPRTVDALWQGS"
     gene            complement(27369..29675)
                     /gene="hcrA"
                     /locus_tag="P5537_00940"
     CDS             complement(27369..29675)
                     /gene="hcrA"
                     /locus_tag="P5537_00940"
                     /EC_number="1.1.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybenzoyl-CoA reductase subunit alpha"
                     /protein_id="HRV76637.1"
                     /translation="MNPRFPKNGTVGARTPLVDGVEKVTGKAKYTADIAAPDAMVGRI
                     LRSPHAHARILSIDTAAAEALEGVFAVCTGAETPVPYGVLPIAENEYPLAREKVRYRG
                     DPVAAVAAIDEATAERALGLIRVEYEVLPAYFTPKAARKAGAVAIHDDKPDNVLREVH
                     AEFGDVAAAFAEADLIREKTYTFAGVNHVHMELNATLAEYDPVRDMLTLNTTTQVPYY
                     VHLKVAACLQMDSARIRVIKPFLGGGFGARTETLHFEIIAALLAHKAKGTVRLVQTRE
                     ETFIAHRGRPWTEVKMKLGLKKDGKIAALALEATQAGGAYAGYGIITILYSGALMHGL
                     YHIPAIKHDAWRVYTNLPPSGAMRGHGTVDTRAAFEALLTEMAEELGIDSLRIRQLNM
                     LPEIPYVTMYAQRVMSYGVPECLEKVKAASGWEERKGRLPKGRGLGIALSHFVSGTST
                     PKHWTGEPHATVNLKLDFDGGITLLTGAADIGQGSNTMASQVAAEVLGVRLDRIRVIS
                     ADSALTPKDNGSYSSRVTFMVGNASISAAEELKGILVKAAAKKLDAREEDIEVIDELF
                     MVSGSQDPGLTFQEVVKAAMVDSGTITVKGTFTCPTEFQGDKRIRGSAIGATMGFCYA
                     AQVVEASVDEITGKVTAHKVWVAVDVGKALNPLAVEGQTQGGVWMGMGQALSEEIVYD
                     KGRMLHGNILDYRVPTMMESPDIEVIIVESLDPNGPFGAKEASEGMLAGFLPAVQEAV
                     YEAVGVRATEFPLSPDRITELLDAKEAA"
     gene            complement(29672..30157)
                     /gene="hcrC"
                     /locus_tag="P5537_00945"
     CDS             complement(29672..30157)
                     /gene="hcrC"
                     /locus_tag="P5537_00945"
                     /EC_number="1.1.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybenzoyl-CoA reductase subunit gamma"
                     /protein_id="HRV76638.1"
                     /translation="MKNILRLTLNGRLREDLVPDNMLLLDYLREAVGLTGTKQGCDGG
                     ECGACTVLVDDRPRLACSTLAHQVAGRKVETVESLSTHGMLSRLQAAFHEKLGTQCGF
                     CTPGMLMASEALLRKNPDPSREDIKTALAGNLCRCTGYVKIIESVEAAAAAQRCAEEA
                     K"
     gene            complement(30154..30663)
                     /locus_tag="P5537_00950"
     CDS             complement(30154..30663)
                     /locus_tag="P5537_00950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HRV76639.1"
                     /translation="MSLEVPIPGERAMVLRGPMADELGFHLRCAQLAAFRHFAQAVGA
                     EEGITPGLYGMLQAIGSNPGLSQSALAVAMDVDRSSIVKVVDRLEEKGLIVRDTSPTD
                     RRRYRLHMTPTGAQALQRIEDAVTRQDRAFSARLDDAERATLIDLLTRLYQPDRETST
                     ARAGLGAES"
     gene            30798..31790
                     /gene="cobS"
                     /locus_tag="P5537_00955"
     CDS             30798..31790
                     /gene="cobS"
                     /locus_tag="P5537_00955"
                     /EC_number="6.6.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051116 - cobaltochelatase activity
                     [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobaltochelatase subunit CobS"
                     /protein_id="HRV76640.1"
                     /translation="MNEPSTPAAPLLPAMPDAECPVRECFGLDSDMRVPAFSKASEHV
                     PQRDDTYRFDPDTTLAILAGFAYNRRVMIQGYHGTGKSTHIEQVAARLNWPCVRINLD
                     SHVSRIDLIGKDAIVLRDGKQVTEFREGILPWAVQHACALVFDEYDAGRPDVMFVIQR
                     VLEVEGRLTLLDQSRVIRPHPAFRLFATANTVGLGDSTGLYHGTQQINQAQMDRWNIV
                     ATLNYLEHDAEVQMVVAKLTAYDTKAGRARVGAMVTLADLTRRGFIEGDLSTVMSPRT
                     VLSWAENALIFGDLRFAFRVSFLNRCDEIERVLVAEYYQRCFGEELIDPRARAG"
     gene            31801..33615
                     /locus_tag="P5537_00960"
     CDS             31801..33615
                     /locus_tag="P5537_00960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobaltochelatase subunit CobT"
                     /protein_id="HRV76641.1"
                     /translation="MAGERSRARALRGTGNTAAFLQALDSTLRAIAGRAGGAANRPDV
                     GGFEGAALPPILTSAEIVRLRGRADALALRLRHHDARLHALQELQGEQARAAYEAIAQ
                     ARVEALATGRMPGVDANIAALIDQQCRDRRLDRASSREQAPLAEALHILARERFLGAP
                     PPPAARAMAELWRPYFDAHVAPRLDELREHLRDEPAFAAGLRELIRALGLEGPASEAR
                     EQRKLARREAEAGEEEAPGPSRAGTPAASDAEPSRRQSAAGREQDGEAAGIDPSAEAE
                     HACAARGEPVRDTPSARRQGASYHAYTTAFDDIADADELCDASELALLRARLDRELTR
                     LPALVGRLARRLQHRLLASRLHDWASDLEEGWLDPARLDRLVVSPDRGLPFRMEKAAA
                     LRDTVVCLLLDNSSSMRGHPLAVAAMSADILARTLERCGIKVEILGFTTRSWKGGRAR
                     ERWLHDGAPAAPGRLAELRHIIYKAADTPWRRARRNLGLMLRDGLPKENIDGEALLWA
                     HRRLLARPEGRRILVVVSDGAPADGATLAANSADYLERHLHDVIASIERRSPVELLAI
                     GIGHDVTRHYRRAVTLRDADELGSALLEQLSRLFDERA"
     gene            33732..34154
                     /locus_tag="P5537_00965"
     CDS             33732..34154
                     /locus_tag="P5537_00965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF971 domain-containing protein"
                     /protein_id="HRV76642.1"
                     /translation="MAGLDENTPTPTDIIVHRDRKTLEVAFDDGSRFELPFEFLRVYS
                     PSAEVRGHGPGQETLQQGKRDVDIVDLAPVGNYAIKPTFSDGHDSGLYSWDYLFAIGH
                     NQEELWNNYLEALERAGGTRDPSKVPPPPPKGGCGHHH"
     gene            34162..34899
                     /gene="ubiE"
                     /locus_tag="P5537_00970"
     CDS             34162..34899
                     /gene="ubiE"
                     /locus_tag="P5537_00970"
                     /EC_number="2.1.1.163"
                     /EC_number="2.1.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional demethylmenaquinone
                     methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol
                     methylase UbiE"
                     /protein_id="HRV76643.1"
                     /translation="MSDKTTHFGFQTVAEELKEKKVAEVFSSVAQKYDVMNDLMSFGL
                     HRLWKHFTIQVSGVREGDRVLDVAGGTADLSLAFAKKVGRSGQVWLTDINHAMLARGR
                     DRMVDHGFAMPAAQCNAEKLPFPDDWFDCVTVAFGLRNMTHKDVALAEMRRVLRPGGR
                     LLVLEFSRVWKPLSPLYDLYSFKLLPWMGEKVANDAESYRYLAESIRMHPGQEELKAM
                     MEQAGLSRVDYFNLSAGVVALHRGYKI"
     gene            34918..35802
                     /locus_tag="P5537_00975"
     CDS             34918..35802
                     /locus_tag="P5537_00975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HRV76644.1"
                     /translation="MKQFFLTLIVAVMSFGFVATEAEAKRLGGGSSFGMQRQATPPAQ
                     RQPSATQQQTPAAGAATAAAQPKRSWMGPIAGLAAGLGLAALFSALGLGEGFANFVMI
                     LLLAAAAFFVFRLIFRRGANAATQQPTRDLQYAGAPAGAAQQARPQQFEAARPLGGGS
                     APAQSGLDKARAGGFDTEGFARQAKLNFIRLQAANDAGNLDDLREFTTPEVFAELCMQ
                     LNERKGAEQRTDVVELNAEVIDVAEENDRYVVSVRFSGLLREQADAAPEAFDEIWHLS
                     KPLAGSAGWLIAGIQQSQ"
     gene            35969..36550
                     /locus_tag="P5537_00980"
     CDS             35969..36550
                     /locus_tag="P5537_00980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SCP2 sterol-binding domain-containing protein"
                     /protein_id="HRV76645.1"
                     /translation="MISSLFLTATNHLLAQAGWARQRLQPHAGRTARLVLSPVAEIDF
                     SVANDGQLAEWSGEEAPEVSLRLAVADLPRLLVDGLETAMRHVRIEGNAEFAEALGFV
                     FRHLRWDAEEDLSRLFGDIAAHRLVEGGRKAIDEGRRGLERASGNVAEYLTEESTLLV
                     PRRALPAFAEEVVALRDAVARLDKRVARLEKRR"
     gene            complement(36704..37129)
                     /locus_tag="P5537_00985"
     CDS             complement(36704..37129)
                     /locus_tag="P5537_00985"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HRV76646.1"
                     /translation="MAMTVHVDIVSAEEQIFSGLAEFVALPGEAGELGILPGHMPLMT
                     RIKPGAVRVRAQNATEEELIFVAGGLLEVQPGLVTVLADTAIRGKDLDEAKALEAKRK
                     AEEAMANQTARLDYAKAQAELMEAVAQLAAIQRLRKRGH"
     gene            complement(37184..38584)
                     /gene="atpD"
                     /locus_tag="P5537_00990"
     CDS             complement(37184..38584)
                     /gene="atpD"
                     /locus_tag="P5537_00990"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015064897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000275 - mitochondrial
                     proton-transporting ATP synthase complex, catalytic sector
                     F(1) [Evidence IEA];
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HRV76647.1"
                     /translation="MSQGTIVQCIGAVVDIQFPRDSMPKVYDALKLEDAADSFAEAGL
                     TFEVQQQLGDGVVRTIALGSSDGLRRGMKVSGTGKPISVPVGMGTLGRIMDVLGRPID
                     DAGPIETDELRAIHQKAPKFDELSPSVELLETGIKVIDLICPFAKGGKVGLFGGAGVG
                     KTVNMMELINNIAKQHSGLSVFAGVGERTREGNDFYHEMKDSNVLDKVAMVFGQMNEP
                     PGNRLRVALTGLTMAERFRDEGRDILFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPT
                     LAEEMGRLQERITSTKVGSITSIQAVYVPADDLTDPSPATTFLHLDSTVVLSRDIAAL
                     GIYPAVDPLDSTSRQLDPLVVGEEHYNVARQVQMTLQKYKELRDIIAILGMDELSPED
                     KLAVARARKIQRFLSQPFHVAEVFTGSPGKYVSLKDTIKGFKMIVSGELDSLPEQAFY
                     MVGGIDEAIEKAKKLQ"
     gene            complement(38611..39480)
                     /gene="atpG"
                     /locus_tag="P5537_00995"
     CDS             complement(38611..39480)
                     /gene="atpG"
                     /locus_tag="P5537_00995"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018678429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HRV76648.1"
                     /translation="MASGKEIRTKIKSVQNTRKITKAMEMVAASKMRKAQDRMRSARP
                     FAEKIRRLAANLSQANVTDYKHPFLVRKDQVKRVGLILVTTDKGLCGGLNTNVQRVAL
                     NAMKDWESSGVTEIRACCIGNKGLGFMQRMGAKVVSNVTQLGDTPHLEKLIGPVKVML
                     DAFQNDELDAVYVAYTRFINTMKQEPVLEQLLPLTGEQLGTPESSWDYLYEPDPQVVI
                     DELLVRYVEALVYQAVAENMASEQSARMVAMKAASDNAKNVIGELQLVYNKTRQAAIT
                     KELSEIVGGAAAV"
     gene            complement(39502..41040)
                     /gene="atpA"
                     /locus_tag="P5537_01000"
     CDS             complement(39502..41040)
                     /gene="atpA"
                     /locus_tag="P5537_01000"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011763893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000275 - mitochondrial
                     proton-transporting ATP synthase complex, catalytic sector
                     F(1) [Evidence IEA];
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HRV76649.1"
                     /translation="MQLNPSEISDLIKSRIQNLQLAATSRNEGTVVSVTDGICRVHGL
                     TDVMQGEMLEFPGNTYGMALNLERDSVGAVVLGEYEHITEGDTVKATGRILEVPVGPE
                     LIGRVVNALGQPIDGKGPINAKLTDKIEKVAPGVIARKSVSQPVQTGLKSVDSMVPIG
                     RGQRELIIGDRQTGKTAVAVDAIINQKGQDMYCVYVAIGQKASTVANVVRKLEENGAM
                     EYTIVVAATASESAAMQYLAAYAGCTMGEYFRDRGMDALIVYDDLTKQAWAYRQVSLL
                     LRRPPGREAYPGDVFYLHSRLLERAARVNEDYVEKFTNGEVKGKTGSLTALPVIETQA
                     GDVSAFVPTNVISITDGQIFLETDLFNAGIRPAINAGISVSRVGGAAQTKVVKKLSGG
                     IRTDLAQYRELAAFAQFASDLDDATRKQLERGRRVTELMKQAQYSPMSIADMAIVLYA
                     VNNGYFDDVDVGRVLAFEAAMIQFVKTKQSALVSSILSKKELDADGEKTLAAAIAEFK
                     KSWA"
     gene            complement(41054..41587)
                     /locus_tag="P5537_01005"
     CDS             complement(41054..41587)
                     /locus_tag="P5537_01005"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HRV76650.1"
                     /translation="MAENVTIARPYADAAFELARGAGALGPWSEALDRLALVAADSGM
                     KACFNDPNLSAEQLYQLVLGVSGDLTAEQQNFVRVLVENERLQVLPEIRDLFVALKNE
                     HEGVREAQIASAFPLDDAALAALKADLEARFKAAVNITVSIDPELIGGVRIAVGDEVI
                     DASVRGKLANMAAALKN"
     gene            complement(41591..42064)
                     /locus_tag="P5537_01010"
     CDS             complement(41591..42064)
                     /locus_tag="P5537_01010"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011763891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HRV76651.1"
                     /translation="MNLNATLIAQLVVFFILAWFTMKFVWPPIVKALDERANKIADGL
                     AAADKAKADLALAEKKVVEELRKARESAGDVRTSAEKQASQLIDEARAEAGRIIAAAR
                     EAAEHEAGAATQRAKEALRDQVAHLAVAGAEKILRREIDAKVHAKLLANLKQELQ"
     gene            complement(42112..42357)
                     /gene="atpE"
                     /locus_tag="P5537_01015"
     CDS             complement(42112..42357)
                     /gene="atpE"
                     /locus_tag="P5537_01015"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002925444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HRV76652.1"
                     /translation="MENVLGFVALAAGLIIGLGAIGACIGIGIMGSKYLEASARQPEL
                     MNALQTKMFLLAGLIDAAFLIGVGIAMMFAFANPFQL"
     gene            complement(42424..43275)
                     /gene="atpB"
                     /locus_tag="P5537_01020"
     CDS             complement(42424..43275)
                     /gene="atpB"
                     /locus_tag="P5537_01020"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HRV76653.1"
                     /translation="MATEGHAPTASEYVIHHLTHLNNTGHAQENIIDWSVINLDSMFY
                     SVVIGALTVFLLWLAARKATSGVPGRFQGIVEILVDMVADQAKGIVHSAESRRFVAPL
                     ALTVFVWIFLMNAMDLLPVDLLPRIWEGMYAAGGGDPAHAYMRVVATADLSATLGMST
                     GVLLLCLYYNIKIKGVGGWVHELFTAPFGSHPLLYPINFAMQIIEFVAKTVSHGMRLF
                     GNMYAGELIFILIALLGSTATVFGFLGHVIAGSIWAIFHILIITLQAFIFMMLTLVYV
                     GQAHESH"
     gene            complement(43278..43619)
                     /locus_tag="P5537_01025"
     CDS             complement(43278..43619)
                     /locus_tag="P5537_01025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HRV76654.1"
                     /translation="MLKAVILQMIATLVAAGLSAALFGVSGAISAAGAGLACVLPSGL
                     FALRLAAITRKTGTATVTAFVAGEFLKIASIVGLLVLVWAVYPDLHWGGMLVGLILAL
                     KANLFAFLVKT"
     gene            complement(43902..44753)
                     /locus_tag="P5537_01030"
     CDS             complement(43902..44753)
                     /locus_tag="P5537_01030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HRV76655.1"
                     /translation="MNKPRLKGLGRGLDALLAANQEEEVDKGELQSLPTIALQPGKYQ
                     PRTRMDPGSLEELAASIKAQGVMQPIMVRPVGEDAFEIIAGERRWRAAQIAGLAEVPC
                     LVREIPDEAALAMSLIENIQREDLNPLEEAGGIQRLIDEFDMTHQQAADAVGRSRPAA
                     SNLLRLLNLAKPVQELLMAGDLDMGHARALLPLDGASQIQLGNQVAARQLSVRDTERL
                     VQQILNPRQKKPAPPPDRDLLRLEEEIADAIGATVKIKANKKGAGELTIRFGSLDQLD
                     GVLGRLR"
     gene            complement(44768..45538)
                     /locus_tag="P5537_01035"
     CDS             complement(44768..45538)
                     /locus_tag="P5537_01035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HRV76656.1"
                     /translation="MAKIFCVANQKGGVGKTTTCVNLAAALHQAGQRVLLIDLDPQGN
                     ATMGSGVDKRELKSSVYHLLVGMVDLAGVRVVSPTGGYDVLPANRDLAGAEVELVNLD
                     QREKRLRNALAAFGDDYDFVLIDCPPSLSMLTLNGLCCATGVIIPMQCEYYALEGLSD
                     LVNTIKKVHANLNRDLKIIGLLRVMFDPRVTLQQQVSNQLEGHFGDKVFRAIVPRNVR
                     LAEAPSHGMPGVVFDKAAKGAQAYMAFAHEMIERAKTF"
     gene            complement(45646..46299)
                     /gene="rsmG"
                     /locus_tag="P5537_01040"
     CDS             complement(45646..46299)
                     /gene="rsmG"
                     /locus_tag="P5537_01040"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002925456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HRV76657.1"
                     /translation="MSGRLQPYAAQLADGVAALGLALPQETIDRLLAFGELLLKWNKV
                     YNLTAIRSPQELITHHLLDSLAVLPQLAAVNRLADIGSGGGLPGVVLAIVRPGLVASS
                     IETVGKKASFQQQAKIELGLGNFTVLNKRVEQVQPEMLPGGAPEGVISRAFSSLADFT
                     GLSGHLVAEGGALYAMKGVNPLDEIAALPAGWAVTETHALTVPGLGAERHLLVIRRA"
     gene            complement(46296..48245)
                     /gene="mnmG"
                     /locus_tag="P5537_01045"
     CDS             complement(46296..48245)
                     /gene="mnmG"
                     /locus_tag="P5537_01045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HRV76658.1"
                     /translation="MLYPTRFDVIVVGGGHAGTEAALAAARMGAATLLLTHNIETLGA
                     MSCNPSIGGIGKGHLVKEVDALGGAMAAATDEGGIQFRILNASKGPAVRATRAQADRV
                     LYKAAIRRRLENQPKLWLFQQAVDDLTVFGDRVTGVVTQIGLRFEAPAVVLTAGTFLN
                     GLVHVGMQNYSAGRAGDPPAISLGQRLKELALPQGRLKTGTPPRLDARTIDFSVMTVQ
                     PGDDPVPVFSFLGHAGQHPRQLPCWMTQTNERTHDVIRANLDRSPMYSGVIEGVGPRY
                     CPSIEDKIHRFADKDQHNIFLEPEGLETHEIYPNGISTSLPFDVQLQIVRSIRGLENA
                     HILRPGYAIEYDYFDPRNLKSSLETKSIAGLFFAGQINGTTGYEEAAAQGLLAGANAA
                     LQVQGREPWCPRRDEAYLGVLVDDLITRGVSEPYRMFTSRAEYRLSLREDNADLRLTE
                     KGRELGLVDDERWAAFCAKREAIERGTAQLKAAWARPEAIPADDQQRVLGKALEREQR
                     YFELLRRPETSYASLMSLPGAPEERETDPQVIEQIEIAAKYQGYIDRQQEEVAKQAQA
                     EATRLPVELDYAQVRGLSKEVQQKLNQHKPETIGQAGRIQGVTPAAISLLLVWLKRRE
                     LAARAGAAAASGEGGGENVAQRPAA"
     gene            complement(48362..49510)
                     /locus_tag="P5537_01050"
     CDS             complement(48362..49510)
                     /locus_tag="P5537_01050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HRV76659.1"
                     /translation="MAANTESGRAMRRIRLNYVLGADTGSAPLHNPLLDLLQAVREQG
                     SISAAARVLELSYRHVWGELKRWELELGQPLILWEKGQAARLSEFGAKLLLAERQVQA
                     RLLPQIEALRADLERAFAIAFDDSVHVLSFHASHDEALAALGEEARTCGLHLDIRFTG
                     SVDAIRALNEGRCTMAGFHLRLPAAPASLSQRTYKPLLRPGLHKLIGFARRSQGLIVA
                     RGNPCGLHGLADLARPGVRFVNRARGTGTRVLFDELLGELGIAPAAIAGYATDEPSHA
                     AVAQAVASGQADAGFGIEASARSRGLDFVPLVEEAYFLACLKSTLEHDATRALLALLR
                     TAAWQERLAALPGYAPMQSGEVLSMSRVLPWWRFGGRAGGHESVRRST"
     gene            49718..50719
                     /locus_tag="P5537_01055"
     CDS             49718..50719
                     /locus_tag="P5537_01055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XdhC family protein"
                     /protein_id="HRV76660.1"
                     /translation="MDSVNLETLRQAVAWQAAGLPVTLATVVRTWGSSPRPEGALLAI
                     CGDGRLAGSVSGGCIEDDLGDRLRTHRLQAPEVVTYGITADQTRRFQLPCGGSLSLVL
                     EPLHAGSRLAEALARIERGELLARRVNLATGTVELLDTAPDSAVVFDDTQLTAAFGPR
                     WRMLIVGAGQLSAYLAQFALALDYRVTLSEPREEYRASWTLPGVDITTEMPDDAVAAM
                     RPDRRSVIVAAAHDPKLDDLALIDALHTDAFYIGAVGSRATSAARRERLRLFDLDDAR
                     IARLHAPAGLPLGSRTPPEIALAIVADLTARRNGASVTATVERPATESAACPLARAA"
     gene            50695..51303
                     /locus_tag="P5537_01060"
     CDS             50695..51303
                     /locus_tag="P5537_01060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HRV76661.1"
                     /translation="MPARTRGLIVGILLAAGAGSRFGGGKLLARLADDRGVAETACAR
                     LLPAVDRVVAVVPAQPGALEDALRAAGAEVVRCDTEAPGMGVSIACGVSASADAAGWL
                     VALGDMPLVPTSQHRVVADALRAGADIAAPVCQGRRGHPVGFAARFGDELRALDGDEG
                     ARAVLARHREALLELAVDDDAGWQDIDTPSDLAAVNRRLGRP"
     gene            51554..52372
                     /gene="fdhD"
                     /locus_tag="P5537_01065"
     CDS             51554..52372
                     /gene="fdhD"
                     /locus_tag="P5537_01065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009326 - formate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0008863 - formate dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_process: GO:0009061 - anaerobic respiration [Evidence
                     IEA];
                     GO_process: GO:0015942 - formate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HRV76662.1"
                     /translation="MLDHPYPASGAHRSYGVERRGTDSAILGEDAVAEEAPVALVYNG
                     FSHAVMLATPQDLEDFALGFTLSEGIAASARELHDIDVVEHALGCEVRMALAGERFAA
                     MRERRRALAGRTGCGLCGIESLAQLQRALPPARLAETAIQPGALERAQAELAALQPLF
                     QLTGAVHAAAWCRRDGSVALVREDVGRHNALDKLIGAIATRGCGFDDGFVLMTSRASY
                     EIVQKAATVGIAAIAALSAPTGMAVRLAEAAGVTLVGFARGHRHSVYTHPQRMH"
     gene            52387..55140
                     /locus_tag="P5537_01070"
     CDS             52387..55140
                     /locus_tag="P5537_01070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HRV76663.1"
                     /translation="MTAATARNERKVPSYCYNCVAGPDFMNVKVIDGVATEIEPNFAA
                     AEVHPARGRVCVKAHGLVQKTYNPHRILQPMKRTNPKKGRNEDPGFVPISWDEALDTI
                     AARLAAVREKGLVDDAGLPRVAASFGHGGTPAMYMGTLPAFLAAWGPIDFSFGSGQGV
                     KCVHSEHLYGEFWHRAFTVAADTPNCRYVISIGSNVDASGGPCAVTRHADARVRGYKR
                     VQVEPHLSVTGACASEWVPIRPKTDPAFMFALIHVLVCEHGVGQLDLPFLRDRTSSPY
                     LVGPDGLYLRDPDSARPLVWDPVAGRAVPFDTPGVQPALEGRFRVAAAVTVDADDARQ
                     PLADVEGVPAHTMLVEHMRKYTPEWAEGICDVPAATIRRIAGEYLENAQIGATIEVDG
                     ATLPLRPVAVTLGKSVNNGWGAFECCWARTVLATLVGALEVPGGTLGTTVRLNRPHDD
                     RHLSVAAGEDGFMAQKFNPTDKAHWVAQPTGRNAHRTLVPIVGNSAWSQALGPTQLAW
                     MFQREVPRDFNMPKPTLPDIWFIYRSNPAISFWDTPSLVETIATFPFTVSFAYTVDET
                     NFFADLLLPEATDLESLQMIKVGGTKFVEQFWTARGVVLRQPAVEPQGEARDFTWIST
                     ELARRTGLLEPYNKAINRGAGGVSPLTGEGYDFSLDPTRTHDVDTIWDAICRAASTDL
                     SQGRETHDLAWFKEHGFYTVPMPQRSWYLTPTLAEKGLRYELPYQERLLRIGRELGNR
                     LHEHGMHWWDTQLSEYTALPEWHDVPGRWEQALVDSGAKPEDYPLWLLATKSMQYHTG
                     GNVSIALMREVAQNVRGHAGVIMNANTAKGLGIADGDRVEIRSHIGATYGKAVLAHGI
                     RPDTLVIPGQFDHWATPVAKDFGMPSLNTVAPMSLELTDATGSGADIVRVAIRRLEGS
                     TVQ"
     gene            55137..55784
                     /locus_tag="P5537_01075"
     CDS             55137..55784
                     /locus_tag="P5537_01075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HRV76664.1"
                     /translation="MTRYVMSIDLRRCVGCQTCTAACKNANATPPGVQWRRVLDLETG
                     EFPDVRRSFLPTACMHCAEPPCAEVCPTEATQKRRDGLVTIDYDVCIGCANCVMACPY
                     EARSIVHEPRFAYGDQPIASEAIRFDPSRISVATKCSFCKERIDAAAASGRIPGRDPE
                     VTPACVNSCISGAMVFGDIDDPDSAVSRLLAKTQHFHMHEELGTGPSVYYIWDHA"
     gene            55784..56689
                     /locus_tag="P5537_01080"
     CDS             55784..56689
                     /locus_tag="P5537_01080"
                     /EC_number="1.8.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004380066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0019645 - anaerobic electron transport
                     chain [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit"
                     /protein_id="HRV76665.1"
                     /translation="MKPNRPPLPGQPAPRLQQHWDWRAAGNFICGGSGGGLVLFAGLA
                     GLTGAEVRPQLAAGLVLVALGLLCVWFEIGRPWRALNVFRHIRSSWMTREASVALALF
                     GAGALALLTAHPTAQALAGLCGLAFVYAQARILAADKGIPAWRHARCAPLVLGSGLAE
                     GAGLIAVTLAGGLQLAAAAVLVLALSARLLLWRRYLDGLRADHAPAASVQAFDAIAPR
                     LVRFGHLLAGGLALLAAAGALGGLPGAGIALAAAGLLAAGAGWWFKYTLIRRAAFTQG
                     IALKHHPVRGGKPASLASTPRLGNA"
     gene            complement(56724..57683)
                     /gene="paaX"
                     /locus_tag="P5537_01085"
     CDS             complement(56724..57683)
                     /gene="paaX"
                     /locus_tag="P5537_01085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetic acid degradation operon negative
                     regulatory protein PaaX"
                     /protein_id="HRV76666.1"
                     /translation="MKSRVIERWVEAHLAGRRISANSLIISVYGDLIAVHGGVVWLAD
                     LIRLMAPFGLNERVVRTSVYRLVQDDWLESGQVGRRSYYRLAAAGMRRFAPAWRRIFE
                     PEGEGWSGTWQVVMLPSALDARVADNLRRELSWAGYGALNAGVLLRPTDDASTLRNIL
                     DGCGLRDRVVPLTARGLDGVTGAATDELVRECWDLQAIAATYDAFIEHFRPLLRAFGA
                     GEVEPEQAFLVQTLLMHEFRRVLLHDPQLPVQVMPNRWRGDAARELCAQLYRLTWRAA
                     CQHLQASCATPEGPLPPPSAQFFRRFGGLESPPAATDEVAVEG"
     gene            57875..58720
                     /locus_tag="P5537_01090"
     CDS             57875..58720
                     /locus_tag="P5537_01090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HRV76667.1"
                     /translation="MTRNTRNTRIARIRRTVAGIATVAIGLFAAPATAQQAASIVVAS
                     TTSTEQSGLFGHILPQFKQATGIDVKVVALGTGQALDVGRRGDADVVFVHDAAAEQKF
                     VDEGHGIEHRKVMYNDFVLIGPKDDPAATKGKDITGALQKLAAANASFVSRGDKSGTH
                     AAELRYWKAAAVDNKGAGYKECGCGMGPALNMAASSGAYVLADRGTWLSFKNRADLAV
                     LVEGDKRLFNQYGVMVVNPERHPHVKQAEARKFVEWVVSPAGQEAIAAYKIEGEQLFF
                     PNAGQ"
     gene            complement(59340..60539)
                     /gene="hmpA"
                     /locus_tag="P5537_01095"
     CDS             complement(59340..60539)
                     /gene="hmpA"
                     /locus_tag="P5537_01095"
                     /EC_number="1.14.12.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008941 - nitric oxide dioxygenase
                     activity [Evidence IEA];
                     GO_function: GO:0019825 - oxygen binding [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0051409 - response to nitrosative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NO-inducible flavohemoprotein"
                     /protein_id="HRV76668.1"
                     /translation="MDARVRELVKATIPVLKEHGVALTTYFYQRMFRHNPELKNIFNQ
                     SHNETGKQPVALAMAVLAYAENIDDPSVLAPVITLIANKHASVGIRAEHYPIVGKHLL
                     ASIREVLGDAASDELIHAWGVAYGALADVFIEAESKLYNEACNSDGGWSGWRSFRIID
                     KVRESEEITSFHLVPCDGGPLPAYRAGQYTTARVFVPELGVTQLRQYTLSIAPGAMHF
                     RISVKREPASTTTPAGRVSNRLHDFYKVGDMLELAPPFGEFFLDETHDGPVVLISGGV
                     GITPMVAMLDRLVATAPSRPVQFVHACRNAAVFAFGAHLARLAERHPQVKLHLFHDEG
                     AAAAPVQSGRVDLRALAGEVLAEGADYYLCGPVGFLEAQIATLHALGVESARIHAEVF
                     DTGGIAT"
     gene            complement(60697..61167)
                     /locus_tag="P5537_01100"
     CDS             complement(60697..61167)
                     /locus_tag="P5537_01100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HRV76669.1"
                     /translation="MQLDRYDRQILELLQQDGRISNQDLADRIALSPSACLRRLRALE
                     ESGLIRGYRALLDARKLGLSLMALIHISMDRHTPERFSHFEAEVEQIPQVLECLLITG
                     QDADYQLKVVVTDMDGYQALLLERITRIPGVTGVHSSFVLRRVIDKTALPLPGA"
     gene            61338..63062
                     /gene="leuA"
                     /locus_tag="P5537_01105"
     CDS             61338..63062
                     /gene="leuA"
                     /locus_tag="P5537_01105"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HRV76670.1"
                     /translation="MMLPNPAAKYRPFAPIALADRQWPNKLIDRAPIWMSTDLRDGNQ
                     ALFEPMNVERKMRMFRTVCEIGFKEIEVGFPSASQTDFDFVRTLIEGGHIPQDVTIQV
                     LTQAREDLIRRTMESVRGAPRAIIHVYNATSPTFREVVFGLEKPQVVALAVSAVRLIK
                     QIGAEMKKECGTEIALEYSPETFSATELEFAREVCDAVTAEWGATPDDKVILNLPATV
                     EVSTPNVYADQVEWMHRHLARRDSVVLSLHPHNDRGSGVAAAELGLMAGADRVEGCLF
                     GNGERTGNVDIVTLALNMYTQGVSPGLDFSDINAVARTVEYCNQLPIHPRHPYVGDLV
                     FTAFSGSHQDAIKKGFAAQKALSGETRPWNVPYLPIDPADVGRSYDSVIRVNSQSGKG
                     GVAYLLETEYGVVMPRRLQVEFSREVQQVTDASGGEMSAAAIWALFRSTYLDTVDPVR
                     YVEHHLFEHGAAQGIRLVVEFGGTRHLLVGEGNGPIDAAVHALRGAGIDVQVRSFEER
                     SVAPSEDGGNASACAFVELSEVGGQGGERYGVGMDANIVTASIRALLSGVNRLQPAFA
                     RAPAARAA"
     gene            complement(63091..63333)
                     /locus_tag="P5537_01110"
     CDS             complement(63091..63333)
                     /locus_tag="P5537_01110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76671.1"
                     /translation="MSFRSGYGQKCAIELYRDATERQAKLAGVTIPTFMCRRCGKRQS
                     VSGRRQVVRGSSRYGYYCASCSTTRAAAAACGNRPS"
     gene            complement(63359..64996)
                     /locus_tag="P5537_01115"
     CDS             complement(63359..64996)
                     /locus_tag="P5537_01115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PEP/pyruvate-binding domain-containing protein"
                     /protein_id="HRV76672.1"
                     /translation="MSADRAVATSTDARRVVRLIHAAAPLPEDCGAAALGSKAWNLAR
                     MAALGLPVPPAFVLGTGWCAEPGALDEAAWRPALAELERLSGLRLGDTRHPLLLSVRS
                     GAPVSMPGMMETLLDIGLTETTLPGLLRVSGHPRLAWDAFRRLIAGYGEVVAGIDARH
                     FDADLDAVRGGCDACDERALDFAALRALAARHLDTYRREAGEAFPQDAHEQLRQAIAA
                     VFASWHADKARTYRAMHGLAEDMGTAVTVQRMVFGNAGGLSGAGVGFTRDPSSGEPRP
                     WVDFLFNAQGEDVVSGRRSAYGHDELAAVAPAVWQALLDATARLERAFGDMQDFEFTV
                     QQGVLHLLQTRTGKRTPRAAARIALDLFDEGVIDAETARARTATLDARVLAEHRIANA
                     DGVALVPLGHAASAASGVACGEIVFDEARARARRAAGAKLILVRQDAETRDLAALELA
                     EGLLTRRGARTSHAAVVARQLGKVCLVGCEALRLDEAERTLEIGGHILREGELLTLDG
                     NEGAIHAGAAAVVEIVPQDLLVRLDALHGRGVGVLQS"
     gene            complement(64993..66921)
                     /locus_tag="P5537_01120"
     CDS             complement(64993..66921)
                     /locus_tag="P5537_01120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF47 family protein"
                     /protein_id="HRV76673.1"
                     /translation="MEKLEAVASLGQAELLRPARVRVALAANDRLKLYLSVLQAAHDH
                     AQRGDAPALDLAREFAAAGVDAPWLAQLPATAYREGKELHVAGLDRLVALLAEDLRTM
                     ARPLEGDEDFDTRCAHWCAWLAELAPDTLSSAQLQALTSGKRGKDDSLHLLVMDLHKA
                     LNRLAAELSSETIDGAHVWQVDALDRPRIAAFMRGLDSTRALKLDHPGLDTAATRDGA
                     RLLLQNDIGTNDAHVLVIQVEGLRVTLTYSDLHRRRFAFFQSLLCEVGASWSEPQART
                     SAGLNFGATYYVGTAGFDCADEEALQRVLEGIGARIVFLIDWNRARKRLEQFVGKTDA
                     TAILAEAARRRVGHMAWLAAGGEQLVFGAMQALGPEYFRIGDRLDGVLGTEKARAFVL
                     ESMALASAATQQRQPLALVADDTRLLLARYLRRHDEFDLLAEHAAYCHALAEGLRDGL
                     AHGHERDRKAAREFSERAKDWERRADQLVMDARARAEARPRWGAFAELVETADDVADA
                     LEEAAFLLSLIAADHHQGWRGEVHQAMQLLADAVLAAAQDHVRALEIARGFGEDSSAE
                     DHEEFVAALWRVLNAERQCDVLLRDVRRALAEHVSDAATLNLSTDFAQALESATDWLL
                     ATGYGLRRLVFSRAGVGR"
     gene            67377..68987
                     /locus_tag="P5537_01125"
     CDS             67377..68987
                     /locus_tag="P5537_01125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HRV76674.1"
                     /translation="MAWLMHPQELGERLAGLGTDLWQLQWHTWRRALGLPSMDPVKPH
                     ADDPRFADPVWTDTATWDLVKEWYLAFTHHVQDMLYETPGLSGKERRRAAFWWRKWLN
                     AVAPTNYLWSNPIALRKFIDTRGHSLWQGWQNMLADLQAGNVRMTDPDGFHVGEDLAT
                     TPGAVIFRNRLLEVIHYAPTRPQVHAEPVVIVTPWINKFYILDLNPRKSMVRFLLDQG
                     LDVYITSWKNPDASMREIRFDDYLAEGISEIVRVAREVSAAERVHAVGYCIGGTALAT
                     WMAWAARHYGEDAVPVRDWTLFTTLVDFHKPGDIEVFIDEESVAHLSAQMNEKGYLDG
                     KDMAASFRLLRSNSLVWHYVVHGWLYGESPAAFDVLYWNMDTTRMPCAMHAWYLRELY
                     LNNRLVQPDALVVASELIDLRRIRQPLYAVAAEDDHIAPWAQTFHTLHHVAADKRFVL
                     SSSGHILGIINPPVTPPKRHYRVATAHRADRAPLWRDRAELREGSWWEDWMAWLKPRA
                     GELVPARPAADERHPALGDAPGTYVLEA"
     gene            69044..69253
                     /locus_tag="P5537_01130"
     CDS             69044..69253
                     /locus_tag="P5537_01130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76675.1"
                     /translation="MQTRGHLATPATPNAMHPGPQLGHGGLDRHTTAAWQARPKKHVA
                     DLLDDAGALADWHRNLERLRHPERG"
     gene            69399..69959
                     /locus_tag="P5537_01135"
     CDS             69399..69959
                     /locus_tag="P5537_01135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004315499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2760 domain-containing protein"
                     /protein_id="HRV76676.1"
                     /translation="MASRNPSFFRRIGLAFSVLFGAELAGRLVRLREQATDAEPPATA
                     GAEEAAAPARPAIVHETTPEAALQLLGLLQRDARFIDFVQEDIGAYSDADIGAAARVV
                     HEGCRKVLDEHFAIAPVRSEAEGSRLTLADGFDAAAVRLTGKVVGKPPFTGTLGHRGW
                     RVTDTRLPALAEGHDASVIAQAEVEL"
     gene            69956..71800
                     /locus_tag="P5537_01140"
     CDS             69956..71800
                     /locus_tag="P5537_01140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp70 family protein"
                     /protein_id="HRV76677.1"
                     /translation="MSAARYTLGIDLGTTHCALSYVDLEASDGDQAAQQVLEIPQLTG
                     PGSIEGRPLLPSFLYLPHADELAPGDLSLPWGATQDHAVGEFARSRGAATPIRLVASA
                     KSWLCHPGVDRRADILPAEAPPEVARISPLTASVRYLSHLRAAWNAAHPEAPFDAQDI
                     TVTIPASFDPAARELTAEAAQAAGYPPVTLLEEPQAALYSWIQRSAGQWRKEVKTGDL
                     ILVVDVGGGTTDLSLIAVLERDGNLELHRVAVGEHILLGGDNMDLALAYTVTRKLAAQ
                     GTRLDPWQTRALAHACRAAKEALLSDSGLDSVPVVVPSRGSKLIGGSIRTEVLREELT
                     ATLVEGFFPRVAVTEQPITRARAALTQLGLPYAQDAAVTRHLAAFLTRQLGATSELDG
                     FAVQPGDAHFLHPTAVLLNGGVLKSVVIAERVLDTLNDWLAADGAAPARLLGGADLDL
                     AVARGAAYYGYVRRGRGVRIRGGTARAYYVGIESSMPAIPGMEPPLEALCVAPFGMEE
                     GSEAALPEQEFGLVVGEPVRLRFFGSSVRRQDEVGTLLDWWTDDELQELEEIEATLPA
                     EGRRPGEVVRVKLHARVTEAGTLELEALPVDGSARWKVQFDVRGTTEA"
     gene            71811..>72345
                     /locus_tag="P5537_01145"
     CDS             71811..>72345
                     /locus_tag="P5537_01145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019920404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HRV76678.1"
                     /translation="MATRYTVGIDLGTSNTVVAFAAAGEDRIQVLEIEQLVGRGELAA
                     RALLPSVRYHPAAGELDPATLRLAASLAGLDEVDKAAVMGAAVVGQYARELGAQVPGR
                     AVASAKSWLSHAGVDRSAAILPWGAAEDVPKVSPVVASASYLAHVRAAWRRRHPEAPL
                     EDQDIVLTVPASFDEGAR"
BASE COUNT        11226 a        25717 c        24580 g        10822 t
ORIGIN      
        1 gcgaatcgcc gcacgccggt cttcgccgcg catggcaccc acgacgacgt cgtcgcgccc
       61 gagctcggcc ggcaggcggt cgagctcctc cgccagctgg gcatcgagcc cgagtggcac
      121 gactaccccc tgccgcattc ggtgagcctc gaggagatcg cggacatcgg gcggtggctg
      181 ggcgccatcc tgcgggcgcc gggccatcac gacggctgat cgcgcggcgc gagcggcgac
      241 tccgctgcgc tcatgccggc cccgcggacg ccgcgcgaca gcctgcgctc acccgctcgc
      301 cgcgcagcag ctcgcgcatc ccctgcccgc tgcgctcgat gcgatagacg cggaaggggt
      361 cgtcctcgtt tacatggcgg tcgagatagc cgctgaagta cagcgccagc ccgcccggcg
      421 cccacgccgc atcgaccacg gtgacgtgct cggcgctcag gcgcaggttc ttgccacggc
      481 cgaggaaacg atcgtggaca aacagcgcgg tgttcggctc gtgcatcgcc tgtcggaagc
      541 gcgcagtgcc gggcaccccg agggtatagg cgaacaccgt cgggtcccgc ggcgagggca
      601 gcacccgatc cgtgctggag atcgcctcgg cctgcacacc gagcatgcgc gcgagcggga
      661 tggattcgcg cacgccgccg ccatcggccg cgatgagcgc gtagtgctcc atgtcgtgca
      721 caccgatcgc gctcccgtcc gcgagccagc ccaggctcca ccactggtgg ttctccgcgt
      781 tggctgcgct ggcgagccga cgtgccgggc tgcccggctc caccaccatc aggtggctgc
      841 gaaagcgcgc gtcggtgagg atgaacgcga gccgcgagcc atccggcgac cacgccgcct
      901 cggagatggc gtcgccctcg cgtcccgcat gcacgcgctg cgcgtcgccg cccgcgagcg
      961 gcagaacgtt cagctgcacc gcctgacgcg tgtcggcggc gggccgcgtg cagtacgcga
     1021 gccgctccgc ggccgcatcg attgcggcgc agccaccttc gaccacctcg cgcgccggac
     1081 cgggcgcctg ccacaacagg atgcgtcccc cgtcctccac cgcgagcacc ggctcacagg
     1141 cggcggcggg gaggcccgac aagccgagca cagccagcag cagggctgcc gcggaaacat
     1201 gccggccgcg cgagcgcagc gcgggaaagg tcgatacggt cattcagtca gccccgacgg
     1261 ccccctctgg caggtcgtcg aacgcggggc aacggccaag cgaccgaaaa ctctgcggat
     1321 cgagaccgtg acgaggtgga aaagcggcac aaaaaaaccg gctcgaggcc ggttgttctg
     1381 cgggatttcg ggggttcgcg tctgcaagcg atttacgcac agcctccagc accgaccgct
     1441 atacccttga tttcttggcg cgcccgagac gattcgaacg tccgacccct gccttcggag
     1501 ggcagtactc tatccagctg agctacgggc gcgcggagcc cggacgaagc gcccggacaa
     1561 ggcgcgagag catagcccgc ttcggcggca aagtccatgc cgcgctgcca caatggtttt
     1621 tagcccgcta taatccgggc tttagaccct gtcttgcgcc acccgtccga ggaccaaagc
     1681 atgtcgaacc cacgcaccct gcggcccgcc cgcctcgcaa tgcccgtcgc cctggtcgca
     1741 gccgcgctgc tggccggctg tggcgaccag agcaagatcg atccggaaac caccgcgacg
     1801 ctgatccagc cggtcgcacg ggtcgagatc caggccgtga ccatcacgcc gggcacccgc
     1861 accggtgagc agatctacaa gtcgatctgc gccgcctgcc acgactcggg tgcggtgggt
     1921 gcgccgaaga cgggcgatgc cgccgcctgg ggcccgcgcc tggcgctcgg ccacgatggc
     1981 ctcaccgcct cggcgatcgc cggcaagggc gcgatgcccc cgcgcggtgg tggcagcgac
     2041 ctcaccgaca ccgaagtctc gcgcgccgtg gcctatctgg cgaacctggc cggcgccggc
     2101 tacaccgaac cgccggtcga gcagtaagcg cgcgagcgca cagcgacgga cgaggcagcc
     2161 tgcgggctgc ctttttcgtg cacgctcgcc gcacgcgccg ccgcgccgtt cagcccttgt
     2221 cgcggctctc gaacatcgcc atcaggttgg cgagccgcgc cttgccctct tccttcgtca
     2281 ccggctgcgc ggtcttgcgg tcgttcatgc ggatgtcgcc gcccatctcg gcgatgaagc
     2341 ggctcggctc gcaggggcgg aactccttgc ccgacttgcg ccgctcgcac caggtgaggt
     2401 tgaggctgcg ctgggcgcgg gtgatgccga cgtacatcag gcgacgctcc tcgtcgacct
     2461 tgtcctcgtc gacgctgctc tggtgcggca gcaggccttc ctcgacaccg accaggaaga
     2521 cgtgcggaaa ctccagcccc ttggaggcgt gcagcgtggc catctgcacg ccgtcgaagt
     2581 cggggtcttc cttgtccagc atggacatca gcgcgatggt ctgggtgagc tcgagcaggt
     2641 tcttgccgtc ctcctcgccc ttccgcccca gccagccgac gaagtcgcgc acgttgctcc
     2701 acttcgactc cgcctcgcgc gtgtcgcagt gctcgaacag ccaggcctcg tagcggatcg
     2761 cgccgagcag gtcttccagc agctgcgccg cgggctcgcg cggggcgcgg tactgcaggc
     2821 ggttgatgta ggcggcgaac tcctgcacgc cctgcagctg cttggcgttg aggtgctggg
     2881 tgagcccttc ctcgaacacc gcggtgaaca ggctgctgtg gcgatgcccg gcgtaggcgc
     2941 cgagcgcctc gatggtggcg gcgccgatgc cgcggcgcgg cgtggtgatg gcgcggatga
     3001 aggcgaggtc gtcgtcctcg ttcaccagca ggcgcagcca ggcgatgagg tcgcggatct
     3061 cggccttgtc gaagaagctc tgcccacccg acatcacgta ggggatgcgg tggttgcgca
     3121 gctgctgctc gatgaggcgg gcctggtggt tgccgcggta gaggatggcg tagtccttga
     3181 agcgggtgcg gtgctcgaac ttgtgcgcga cgatcttggt cgccacccac tccgcctcat
     3241 gctcggcgtc gcggcagttg gtgacgacga tctgctcacc ctggccgtgc tcggaccaca
     3301 ggcgcttgtc gaagagcttc tcgttgttgg cgatgacggt gttggcggcc tcgaggatgc
     3361 ggcgcgagga gcggtagttc tgctcgagct tgatgacctt gagcttgggg tagtcctgct
     3421 gcagcagctt caggttctcg acgtcggcgc cacgccatgc gtagatcgcc tggtcgtcgt
     3481 cgcccaccgc ggtgaaggcg ccgcgcacgc ccgacagcag cttgagcagc cggtactggg
     3541 cgcggttggt gtcctggtac tcgtccacca gcaggtagcg cagcttgttc tgccagcgct
     3601 cgcgcacctc ggggtgctcg tcgaacaggc gcaccggcag cgagatgagg tcgtcgaaat
     3661 ccaccgcctg gtaggcacgc agggtgcgct cgtattcctt gtagagcttg gcggcgaccg
     3721 aggcgatctc gttgtcggcg agctgggcgg cctcctcggg ggtgatcatc gcgttcttcc
     3781 acgacgagat ctgccactgc atctgcttgg cgatgccctt gtcgctgtcg ccggccacgt
     3841 ccgagacgat ctgcacggtg tcggacgcat cgaggatgga gaactgcggc ttgagcccgc
     3901 agtgcttggc ctcctggcgg atgatgcgca cgccgagcgc gtggaaggtg cacaccgtga
     3961 gcccgcccgg cacgcgcccg cccatgatgt gggcgacgcg ctcctgcatc tccttggcgg
     4021 ccttgttggt gaaggtgatc gcggcgatgt tgttggcgct gatgccgcac tcgttgatca
     4081 ggtgcgcgat cttgtgcgtg atcacccgcg tcttgccgct gccggcgccg gccagtacca
     4141 ggcaggggcc gtcgagatag cggatcgctt cgcgctgggg cgcgttgagg agggcggaca
     4201 tcgtgaactg gatcgcagaa aagcaaagcc gcccggccgg gcggcgtgga cgtcgattct
     4261 agccgatcgc gcgtccgggt cggcggacac gggccggacc acgccgaggg cggggcggcg
     4321 tgcgcccggc cggcgaggcg ctcaaagatg ttccttgcgc cgcagcacca gcggacggcc
     4381 gtcgtgcgac ttcttcacca gccaggtagc gagcgccgag tccatgtagt cggcgtgccc
     4441 ggggaaccag tccatcagcg cctgcgcgag ctcgcgggcg atcgccacct cgcccttgcc
     4501 gacgagctcc tgcacctcgc gcaccgaggc catcaccttg gcgtgctcgt cgatgtggca
     4561 ctcgccgccg ttggggaaat cgggcgcggc cagccactgg tcctcctgcg cgaagtgcgc
     4621 ctcggcgtgg cgggcgaagg cgtcgagcgc ggcggggatc tccgcgtcgc tggcgcgcag
     4681 cagcgcatcc acgcaatcga cgaactcgcg gtgagtgtcg tcgatcgtgc ggtgcccgag
     4741 caggaaacgg tcactccagg tgaacacggg cgggttggtc attgcggtct tacctcggct
     4801 tgaacaggag caaaaaacgg ggccgggacc ttggtcgcag cgccctgatg aatcaagtct
     4861 agcaagaccg ggcacctttg cagacagcgt ctgtccgaca gcgcaagggt gacaagcctc
     4921 ggtggctcgc tcaaaatcgc ccgcaaagcg cctgccgccg cgcacttcaa ccgttccgga
     4981 ccttgccatg aagctcaaga tcgccgccgc cgtcgcggtc ctcatcctcg ccgtcgccgg
     5041 ctttttcgtg ttcacccaga agccggccgc acccgacgtg accttctcca cgctgcaggg
     5101 acagagcttc cgcaccgccg acctgcgcgg caaggtggtg ctggtgaact tctgggccac
     5161 cacctgcacc agctgcatca aggagatgcc ggcgctgaag gcgacccagg agaggttcga
     5221 ggcgcgcggc taccggaccg tggcggtggc gatggactac gacccgcccg cccaggtcgc
     5281 cgccttcgtc gagcgcagcg cgctgccctt caccttcgtg ctcgaccgcg acggcagcat
     5341 cgcgcgcggc ttcgagggcg tgcgcctgac gccgaccagc tacgtcctcg accggcgcgg
     5401 ccagatcgtg cagaagatcc tcggcgagcc cgacttcgac aagctgcacg gcctgctcga
     5461 gcaactcctc gccgaacccg cctgacagga aagcccacgc tccccatgcc catgatccgc
     5521 gccacgctgc acgcagctct ttcggccagt ctcctgctcg ccctgctccc gcccgcccac
     5581 gcccagcgca gcggcaacat cggcggctgc gacatccgcc gcggcaccct gtgcaccaac
     5641 ctcaacctca acggggcgaa cctcgaaggg gtgaacctgg ccaactcgca gttcacccgc
     5701 tcggacctgt ccggcgccaa cctgcgcggc gccacgctga acgaggcgaa cttctcccag
     5761 gccgagatgg cgggcgcgac gctagacggc gcctcgatgc tgcgcaccaa cctgcgcggc
     5821 gcacgcctga ccggcgccag cttcaaggaa gccgacctgc gcaacgcgat cctgcagaac
     5881 gccgacctgc acgacgccga cctctccgcc gccaagctcg gcggcgccga cctcaccaac
     5941 gcgcgcgccg agcgcagccg cttcgacggc gccgagctca cccgcagcaa cctgcgcgcc
     6001 gccaagctcg cgggcgcctc cttcgcgggc gccaacctgc agggcgccaa cttcacccgc
     6061 gcgcagctca gcaacgccga cctcaccggc gccaacctcg accaggcgat cttcctcaac
     6121 gcgcagacgg acggctgcaa gggctgcccc tgatcgacca tgggcggcgg gcatgcgccg
     6181 ggggaggcct gcccggcgtc gcccgcgacc gccgccatgt tccagcagcg cgtgctcggg
     6241 tcgcgcggcg cgccctactc gaggccgaac tggaaggtgc tgaccacgcg caggcgcttg
     6301 ccgatcgtgc gcgacgtgtc catgtcggag tcgtcgtcgt cggtgatgcg gatcgcgccc
     6361 tggtttgcgc tgcgcagggg gcccaggcgc gcgcccgcat cggccgcgaa cttgctggcc
     6421 agttcgcgcg cgctcagggt cgcctcttcg agcaggatgg gcttgatgtc gttgaagccg
     6481 cgcagctggt agcgcggcgt accgtcgctg ccatcacccc ccagctgcac gcccgcctcg
     6541 accagcggat cgacccgatt cgacgccgcg gccacgagat cgacgcgggc cgacttgacc
     6601 acgacctgcc cctgcccggt gaagcgcagg gccacgcggt ccgatccata ctcgcgcgcc
     6661 aacagatcct gcacctgcaa gggccgcacc tcgatctcgt cgtcgctgaa gccctgctcg
     6721 cgcaggaagg cgaccacgcg ctcgcggtcg gcggtcaggg cctgctgcac gctgccgaag
     6781 tcgttctcgg cgcggcggaa ggggacggtc cacaccgcga agtcgctctt cacgtcacgc
     6841 tcggccaggc ccttcacggt gagggtgcgc tccgccatgc ggaaacgctc gatgcctccc
     6901 gccacctgca tgccggcaaa gccgatgccg gcggccagga tgagcgccgg aacgatcccg
     6961 atccgaccct cggccatgat cacaccaccc cggcgccgtg cgcctgctgg tcggcccagt
     7021 agctcgagcg caccatcggg ccgcaggcag cgttcttgaa gcccatcttc agcgcttcgg
     7081 tctcgaacat cttgaaggtg tccgggtgca cgtagcgcag cacgggcagg tgaccgccgg
     7141 agggctgcag gtactggccg atggtgagca tctcgacgtc gtgggcgcgc aggtcgcgca
     7201 tgacctcgag gatctcgtcg tcggtctcgc ccaggcccac catcaggccc gacttggtcg
     7261 ccacgtccgg atggcgcgcc ttgaactgct tgagcagctc gagcgagtac gcgtagtccg
     7321 agcccgggcg cgcctgcttg tagaggcgcg gcacggtctc gaggttgtgg ttcatgacgt
     7381 cgggcggggc ggcgtcgaag atgtcgaggg cgatctccat gcggccgcgg aagtcgggca
     7441 ccagcacctc gatgcgggtc ttgggcgagg ccgcgcgcgt ctcgcggatg cagtcgacga
     7501 agtgctgggc gccaccgtcg cgcaggtcgt cgcggtcgac cgaggtgatc acgacgtagt
     7561 tgagacgcat cgcggcgatg gtcttggcga ggtcgcgcgg ctcgtcggcg ttgagcggct
     7621 cggggcggcc gtggccgacg tcgcagaacg ggcaacggcg ggtgcagatg tcgcccatga
     7681 tcatgaaggt ggccgtgccc ttgccgaagc attcgtggat gttcgggcag gaggcttcct
     7741 cgcacacggt gtgcagcttg tggtcgcgca gcgtggcctt gatctcgttg aagcgctcgg
     7801 cctccatgcc ggcgccgagc ttgatgcgga tccagtcggg tttcttgagg cgttcggcgg
     7861 ggacgatctt gatcgggatg cgggcggtct tgtcggcgcc gcgctgcttg cgcgctgggg
     7921 tttccatggt cgctgttctc tgtgggtttc cgggtgggaa ggggctgatc tcggacggat
     7981 ccgtcggcgc gattatgacc cggcacgcgc cgccacggcg acgggcgagg ccgcagccgc
     8041 attatcggtt tccccaatgt ccgacgatgg gggcggcagc aggcgctgca ggtggccgag
     8101 cagcacctcg ccgacctgct ccacgcccgc gtcgacgccg aagtccttca tgcggatcgt
     8161 cttcaggccc tcgtagccgc aggggttgat ccagccgaag ggggcgaggt cggcgtccac
     8221 gttgatcgcc aggccgtggt agctgcagcc gttgcgaacg cgcaggccta gcgcggcgat
     8281 cttgtcgccg gcgacgtaga cgcccggcgc gccgtccttg cgctcggcct cgatgccgta
     8341 gtccgccagg gtgtcgatga tcgcctgctc catcaggttc accagctcgc gcaccttgag
     8401 ccggcggcgc ggcaggtcga gaagcagata agcgacgagc tggccggggc cgtggtaggt
     8461 gatctggccg ccgcggtcga tgtgcaccag cgggatgttg gccgggttct gcagcaggtg
     8521 ctcgggcttg ccggcctggc cgagcgtgta caccggcggg tgctgcagca gccagagctc
     8581 gtcgggcgtg tcggccccgc gctgggcggt gaacacgcgc atcgcctcga gcgccggcgc
     8641 gtactccacc aagccgaggc gcttgacgat cacagcacca ccttgaccat cgggtgcgcg
     8701 gtgagctcgc ggtacatcgc gtccacctgc acctgcgaca ccgcgcggaa ggtgcaggtc
     8761 accgcgaggt agttgccctt gctcgagggg cgcatctcgg cgccggcggg ctcgaagtcg
     8821 ggcgcgtggc gcagcaccac ctcgatcacc gcctgggcga agccgtccac ccgcgcgccc
     8881 atcaccttga tgggaaagtc gcagggatac tcgatcaggc tctggcgcgt ctgcgcgtcc
     8941 tgctggtcag ccatggcaca tcaccgtatt cgtcgatttc tggtcgagcg ctcagaggct
     9001 cttgaagaac atcacgatcg catcccacag gcggccgaag aagcccgcca cctcggcgtc
     9061 ctgcagggcg accaccgggt actggccgag cggcttgccg tcgatcgcga cggtcagcgt
     9121 gccgacctcc tggccgcgct gcagcggcgc caccagcggc tggcggctct ccaggctgac
     9181 ctggatcttg ttcgccgcct ccttgggcac ggtgagcgcg aagtcgttca ggaagcccac
     9241 cggcagctcg ttgagcttgc ccttccagac gcggaacttc gacagcgcct cgtcggcgga
     9301 gtagagcttc accgtctcga agaactgata gccgaagttg agcagcttga gcgactcctg
     9361 cgcgcgcacg gtgtccgagg cggcaccgag caccaccgag atcaggcggc gctcgccgcg
     9421 gcgggcggtg gacaccaggc agtagccggc gctgctggtg tggccggtct tcatgccgtc
     9481 gaccgagggg tccatgtaca gcaggcggtt gcggttgggc tgcttgatgc cgttgtaggt
     9541 gaactccttg agcgagtaca ggctgtagta ctcggggaag tcgcggatga tcgcgctcgc
     9601 cagcagggcg aggtcgcgcg cgctggtgta cagctgcggg tcgggcaggc cggtggagtt
     9661 ggtgaagtgg gtgttggtca tgcccaggcg ctgcgcctcg cggttcatca gcgcggcgaa
     9721 ggcctcctcg ctgccggcga tggtctcggc gagcgccacg caggcgtcgt tgccggactg
     9781 cacgatcacg ccgcggatca gctcgtccac gctgaccggc ttgttgggct cgatgaacat
     9841 gcgcgagccc tccatgcgcc aggccttcgt cgacaccggc accacctggt cgggcttcag
     9901 cgtgccttcc ttgagcttgg agaaggtgat gtaggccgtc atcagcttgg tgagcgatgc
     9961 cggctcgatg cgggcgtcgg cgtccttctc ggcaagcacc tgtgcggtgg catggtcgac
    10021 cagcgcccag gccttggcgg ccagcgcggg gggcggcacc gtctgcgcga gcgcggacag
    10081 cgagaacagc gagacgagga cggcaatcag gaaacgcatt ggaaaaacct ggggagacgg
    10141 gaaagggaac ggcgaattat aggcgccacg catgtacggg ccaaaaatgg aaagcctttg
    10201 ttgcaacccg gacgcggcgg gccgagctca gcgcaccacc acgaatggct tgagcttgag
    10261 cacgttgccc atgcgcgcgg cggcgtcgcg tgccgcctcg accgtatcgt agggaccggc
    10321 gtggaggcgg aaacgttcgc catcggtgaa caactcgaaa cgctcggcca ggttcgaggc
    10381 ctggctgcgc accgtgtcgc ggaaaccttc ggcgttggcg aacgaggaga aggcaccgag
    10441 ctgcaggaag atgcccgcgc tcgccgaggc gaccggcggc gcgaagccgc ccgcggcgcc
    10501 gcaggccggg ccttcctcgc actcgggcgg agcgatcgcg gtgtcggcgg gacgtaccgg
    10561 gctcgccgct ggcgctgcaa gcggagcctg cgcgaccggc agcggggcga gcggcttcat
    10621 tccgatcacg ggccccaccc ccgggaccag cccctcgttg gcgcgcgcac gcagcggtgg
    10681 caccggccgc gccgcagcca ccagcggcgc ctcgccgggc aggatctgct cgacctcgac
    10741 ttcggcgctg ccgctgttga tgtaccccag cttgtgcgcc gcggcgtagg agaggtcgat
    10801 cacgcggcca cgcaggaagg ggccgcggtc attgacccgc accaccaccg agcggccatt
    10861 gccgagattc gtcacgcgcg catagctcgg gatcggcagg gtcggatgcg cggcggtcat
    10921 cgcgtacatg tcgtagggct cgccgctcga ggtcggcttg ccgtggaagc ggcggccgta
    10981 ccagctgccg tggccgcgct ggcggaaggc gcgcaccgcg gtggcgggca cgaagctctg
    11041 ccccatgacg tgatacggac ggttggcgta gcgatggagc ggctcgtcgc gcggctcggc
    11101 gtccgggatc gcgtcgaggt cgtcggggat ctcgtcctcg gggccatcgt ccttgtaata
    11161 gcccccgccg cgacgcgccg ggctgcgctc cggcgtcccg gcccgagccg gcgcctcggc
    11221 gaccggcccc tcgcgcctgg gcgcggaacc gcaggccgtc agcaaggctg cggcgcaggc
    11281 gacgccgagc atggccaggg cgcggcgcgc ccgaagccct gaggcacggg cagcgggagg
    11341 caggggagga actggagtca tcgtcgttcg gggccttctc aggtcttgtc cgcgaagcgg
    11401 ctgcgctgga tgctcatgag gatgccgatc cccaggcaga gcgtgacgag cgcggttccg
    11461 ccgtagctga tgaagggcaa tggcaccccc accaccggca ggatgccgct caccataccc
    11521 atgttcacga aggcataggt gaagaagatc atcgtgatcg ccccggcgag caggcgcgcg
    11581 gcgtgggtgg gcgcgttggc ggcgatgtgg aagccgcgca gcagcagcag cacgtagacc
    11641 gcgagcagca ccagcgcgcc gacgaggccg aactcctcgg cgagcacggc aaagatgaag
    11701 tcggtgtggc gttcgggcag gaaggcgagg tgggtctgcg tgccgtccat ccagcccttg
    11761 ccggtgagcc cgccggagcc gatcgcgatg gtcgactgga tgatgtggaa gcccttgccg
    11821 agcgggtcgc gggtgggatc gagcagcgtg cacacgcgct gcttctggta ttcgcgcagc
    11881 acctgccagt cgacttcggg ctggcacagg gtgtcgccga aggcgacgat cgaacccagc
    11941 ccgatcacca gcgccaccat cagcgggatc agcagcttcc acgacagccc ggcgaagtag
    12001 atcacgtaca gccccgaggc ggcgatcagc aggctggtgc cgaggtcggg ctggatcacg
    12061 atcaggccga ccggcaccag cagcagggcg ccggcgagga tgaagtcgat gaagcgggtc
    12121 tggccttcgc gcatctggaa gaaccaggcc agcatcagcg gcatcgcgat cttcatcagc
    12181 tccgagggct ggatgcgcgc cacaccgagg tcgagccagc gctgcgcgcc cttggagacc
    12241 tcgccgaaca gctccaccgc caccagcagc accacgccga gcaggtagag cggcaccgcc
    12301 atcgacagca ggcgctgcgg cttgagccag gccagcaccc acatgccggc gagcgcgatg
    12361 ccgatatggg tgatctgcga gtcgaggcgc tcgggcgagg cgctttgcat gagcacgtgg
    12421 gcgtagccga gcagggcggc gagcacgaac atcagcaccg gatcgagcgg gcgcaggaag
    12481 ccgagcacga gcgcgagcgg gttgaagcgg ttgtcgttca tcgcgcgctc ctcgccgcgg
    12541 cgggctgcgg cgcgggcacc gcggcaggcg gggtggccgg gcgcgacggc acgggcgcgg
    12601 gcggcgcctc cagcggcaac gccggctcga cgatccgcga ggccggcagc gcgtcgcctc
    12661 cactctccgc accctcctcg ctctcggcac cttcctcgtc ctcggcagcc ggggcacccg
    12721 cacgctggtc gagcaggtag tagtcgatca cctggcgtgc gatcggcgcc gccgactggg
    12781 cgccgaagcc gccgttctcg accagcaccg cgagcgcgat cctggggttc tcggccgggg
    12841 cgtaggcgac gaaccaggag tggtcgcgca ggcgctcgcg cacgcggccc tcgacgtagc
    12901 gctggccgcg cagcgagaac acctgcgcgg tgccggtctt gccgccgacg gtgtagggcg
    12961 cacccttgaa cgcacgcttg ccggtgcccg tgcggttgac gtccaccatg gcgtcgagca
    13021 ccgccttcag gtgtgcgtcg cgcagcggga tctggcgcag cggctcgggc tcgaccgcgc
    13081 gccgctcgcc ggtgcgcgaa tccaccacgt acttgaccac gtgcgggcgg aacagcttgc
    13141 cctggttgac cagcgcggcg agcgcgttgg cgagttgcag cggcgtgtag gcgttgtagc
    13201 cctggccgat gccgaccgag atcgtctcgc ccgcgaacca gcgctgctgc tcgggcttct
    13261 tgaagcgatt gcgcttccac tccggcgagg gcagcacgcc ggtcgcctcg cccggcaggt
    13321 cgatgccggt gcgctcgcca aagccgaagg gcgccatgaa gccggcgatg ccctcgatgc
    13381 cgaggtcgtt ggcgagctgg tagtagtagg tgttgcacga caccacgatc gacttgtgca
    13441 ggtccaccat gccgtggccg ccgatcttgt cgtccatgaa gcggtggccg ccgaactgga
    13501 aatagccgac gtcgtacatg gcctgcttcg cggtgcgctt gccggtctcg aggccggcga
    13561 gcgccatgaa gggcttgaag gtggagccgg gcgggtaggt ggagtagatc gcacggtgca
    13621 gcatcggatg gtcgggcgag tcgttgagcg ccttccagtc ctgggtcgag atgccgtcaa
    13681 cgaagaggtt tgggtcgtag gtcggcatcg aggccagcgc gagcacgccg ccggtggaag
    13741 gctcgatcgc caccagggcg ccgcggcgat cgccgaaggc cttctcggcc accttctgca
    13801 gctcgatgtc gagggtgagc tcgaggtcgt tgcccggcgt cgccgcggtg tgcgacagcg
    13861 cgcgcaccgc gcggccgccg gcgttgacct cgacctgctc gaagccggtg gtgccgtgca
    13921 gctcgtgctc gtaggactgc tccaggccgg ccttgcccat gtgcagggtg ccgcggtagt
    13981 tggccgcatt gccggcctcc tcgatgcgct cgacgtcgcg ctcggtgacg cggccgatgt
    14041 agccgatcac gtgcgaggcg gtactgccct gcgggtagtc gcgcagcagg cgcgccttca
    14101 cgtccacccc gggcaggcgg tagcgctgcg acaccacgcg cgcgacctcc tcgtcggtga
    14161 gccggctgcg cagcggcacg ctctcgaagt tgcggctctc ctcgtagagc ttgcggaagc
    14221 ggcggcggtc gcgcgcgtcg agcggcagga ggccggcgag ctcgtcgagc gtggcgtcga
    14281 ggttgcgcac ctgcgagggc gtgatctcga tcgtgtaggt ggcgtagttg cgcgccagca
    14341 ccaccccgcg ccggtcgacg atggtgccgc ggtgcggcac caccggcagc agcgcgatgc
    14401 ggttgtcctc ggcgcgggtg aggaagtagt cgtggcgctt gacctgcagg tgatggaagc
    14461 gcgcggcgag cagcccgaag cagacgagca cgaacaccgc cgccaccacg acgcgaagcc
    14521 ggaagcgggc cagttcggcc gcgggcgcgc gaaactcggt catcgcccgc gcgcctcaga
    14581 tcgggcggtt gtcatcgcgc tcgtccggct ggtactgcgg cagcaggagc aggaaggaga
    14641 gcggcgccca cagcagcgcg ctgcccaggc tagacaggaa atacgaccag cccgggaact
    14701 ccgccccggc cagcaggcgc accagcacca tgatcgcctg cgcgagcagc agcagcggca
    14761 gcacgtgcag ggcctgctgc caggcgggga accacagcac gcggcgggcg agcgcgttgg
    14821 ccaggtaggc gagcacgacg taggcgagcg catgctggcc catcgccgcg ccgaggccga
    14881 cgtccatcag caggccgaag gcaaagcccg cgcccatgcc gatcgcgagc ggctcgcgca
    14941 cgcaccagaa ggccagcacc agcgccaccc agtcgggcag gccgggcgtg cgtccggtgg
    15001 ggatgtactc caggccgagc gccacgaaca ggctcaggta gacgaaccag agcttgaccg
    15061 gctgcaggat gcggctggaa cggttggtcg ggtgcatggt tcagcgttcc cccgcgggtt
    15121 cgggcggcgg cgggggcggc ggatacgcgg cacgcccgat cacgagcacc tgcacgctgc
    15181 gctcgatcgc cgccagcggc tcgcactcga tgcgtgcgaa cgcgtcctgg tcgcgatcga
    15241 cccgggtcac cgtcgccacc ggcagcccgg gcacgaagat gccgtcgagg ccggaggtga
    15301 cgaggcgatc gccgggctgg atgtccacct cggcgagcac gtggcgcatc tcgagcatgc
    15361 cgcggccgac gccgtagagc acgccgcgca cgccgttgcg caccacgctg accgggatgg
    15421 actggttgcg gtcggtgagc agggtgacct cggactgcac cggatggacg cgggtgacct
    15481 gcccgatcac gccgttcgcg tcgaccaccg cgaggccggc ctcgacgccc tgctgggtgc
    15541 cgcggtcgag gatcaccttg cgcgcgaagg ggtcgggcgc gttgtagagg atgtcggcgg
    15601 cgatgctctt cgtctgcacg cgctcggaca tctgcagcag ctcgcgcagg tgcaggttct
    15661 cctgttcgag ctgctcgaag cgcagcaggc gctcgccggc atcgagctgg aggcggcgca
    15721 ggtcggcgtt ctcgagctgc acatcgacca gggtgccgaa gtagcgcgtg gcgttgcgca
    15781 ccacgtcggc cggcgtcgac gccgccatct gcagcggata ggtgaccacc gacagcgcgt
    15841 tgcgcagcac ctcgaggtag cggaagcgca ggtcggccac gagcagcacg aggcacagcg
    15901 cgacgaacac gaacaggcgc gcgagcggcg ccgggccgcg gcgaaagatg ggagggggct
    15961 gatggccgac gagagacatc cgctacgaac cagggccgtc aggtggggag ggaagacgcg
    16021 ccccggcacg caggccgggg ccggaggacg tcactcggac gtgaagatgg aggcgagctt
    16081 gtccatcttg tcgagcgcca tgccgcagcc gcgcgcgacg caggtcagcg gctcctcggc
    16141 caccaccacc ggcaggccgg tctcttccat cagcaggcgg tcgaggtcgc gcaccagggc
    16201 gccgccaccg gtgagcatca tgccgcgctc ggcgatgtcg gcgccgagct cgggcggcgt
    16261 ctgctcgagg ccgatcttga ccgcggagac aatctggttg agcggctcgg tgagcgcctc
    16321 gaggatctcg ttggacgaga tcgtgaagct gcgcgggatg ccctcggcca ggttgcggcc
    16381 cttgacctcc atctcgcgca cctcggagcc ggggaaggcg gaaccgatct ccttcttgat
    16441 cttctcggcg gtggtctcgc cgatcagcat gccgtagttg cggcggatgt agttgacgat
    16501 ggactcgtcg aacttgtcgc cgccgacgcg gatgctgccc gaatagacga tgccgccgag
    16561 cgagatcacg ccgacctcgg tggtgccgcc gccgatgtcg accaccatcg agccggtcgc
    16621 gtccgacacc ggcaggccgg cgccgatcgc cgcggccatc ggctcctcga tgaggaagac
    16681 ctgcgaggcg ccggccgcga gggccgcgtc gcggatcgcg cggcgctcga cctgggtgga
    16741 cccgcagggc acgcagatga tgatgcgcgg ggagggcgag agcaggcggg agtcgtgcac
    16801 cttcttgatg aactgcttga tcatctgctc ggtgacgacg aagtcggcga tcacgccgtc
    16861 cttcatcggg cggatcgcgg tgatgttgcc gggcgtcttg ccgagcatct gcttggccga
    16921 gtggccgacc gcctggatgg agcgcttggc gttgggacca ccctcggtac ggattgcgac
    16981 caccgagggc tcgtccagca cgatgccctt gccgcgcacg tagatcaggg tgttggcggt
    17041 gccgaggtcg atcgcgagat cgttggagaa gtaggagcgc aggaaaccga acatgaagcc
    17101 ttccgaaacc ggtggagtgg tcgagccgcg cacagccggg cacccttggc gcgctgcaac
    17161 gcgaaaaccc cgcccgctac cgcgaagcgg cgcagccccg ggcggggcaa agacgattat
    17221 gataacctac aaacctttgt cgattcagca ggttttgtta cgccatgtcg ctctccaatg
    17281 accaggtcgg gcacatcgcc cgcctcgcgc gaatcgccgt ctccgcgtcc gaactcgagg
    17341 ccacgcgcga caagctcaac ggcatcttcg gcctcatcga gcagatgcag gcggtcgaca
    17401 ccagcggcgt cgagccgatg agccatccgc aggagctcgc cacccgcctg cgccccgacc
    17461 tcgtcaccga ggccgaccgc cgcgaggcct tccagaaagt cgcgccgcag accgaagccg
    17521 gcctctacct ggtgccgaaa gtcatcgaat gatccgctcc gcggcctccc tccgcgtcgc
    17581 tgccccagac cgcatcgacc gcacgcgtgc cgcggcgtca acctgcctga ccgaaaaatg
    17641 atcaacgcct cccttccgga actgcgccgc gcactcgacg cccgccagat ctccgccgtc
    17701 gagctcgccg gcctgttcct cgaccgcatc gacgcgctga accccgcgct caacgccttc
    17761 atcaccgtcg accgcgaggg cgcgctcgcc gccgcgcaca ccgccgacca acgcatcgcc
    17821 gccggcagcg ccgggccgct caccggcatc ccgctcgcgc acaaggacgt gttctgcacc
    17881 gaaggcgtgc tgaccacctg cggctcgaag atgctggcca acttcgtcag cccctacgat
    17941 gcccacgtgg tgagcctgct caaggccgcc ggcgcggtga gcctgggcaa ggccaacatg
    18001 gacgagttcg cgatgggctc gtcgaacgag agctcgtact acggcgcggt gaagaacccg
    18061 tggaacccgg agcgcatccc cggcggctcg tccggcggct cggccgccgc ggtggcagcg
    18121 cgcctggcgc cgatcgccac cggcaccgac accggcggct cggtgcgcca gccggcgtcc
    18181 tattgcggca ttaccggcat caagcccacc tacggcctgg tcagccgcta cggcatgatc
    18241 gcctacgcct cctcgctcga ccagggcggt gccttcggcg ccagcgccga ggactgcgcg
    18301 ctgctgctgt cggcgatgac cggcttcgac gagcgcgact ccaccagcct ggagcgcccg
    18361 accgaggact acgccgccgc gctcgccggc ccggcctcca cccgcccgct cgagggcctc
    18421 accatcggcc tgccgcgcga gttcttcgcc gagggcatgg ccgacgacgt gcgcgccacc
    18481 atcgacgccg cgatcgcgca gtaccgcgcg ctcggcgcca ccacggtcga ggtctcgctg
    18541 cccaacgcca ggctggcgat cccggcctac tacgtaatcg cgccagccga gtgctcgagc
    18601 aacctgtccc gcttcgacgg cgtgcgctac ggccaccgcg ccgccgacta cggcgacctc
    18661 gccgacatgt acgcgaagag ccgcgccgag ggcttcggcg ccgaggtcaa gcgccgcatc
    18721 ctggtcggca cctacgtgct ctcgcacggc tactacgacg cctactacct gcaggcgcag
    18781 cgcctgcgcc gcctgatcgc gcaggacttc caggccgcgc tgcagcactg cgacctcatc
    18841 gccggcccga ccacgccgac caccgcctgg gcgctcggcg agaaggccga cgacccggtg
    18901 cagatgtacc tgtccgacat ctacaccatc gcggtgaacc tcgccggcct gcccggcctg
    18961 tcgcacccgg ccggcttcgg cgccgacggc ctgccagtgg ggctgcaact gatcggtgac
    19021 tatttcgccg agtcgcgcct gctgaacgcc gcacaccgct tccagcaggc caccgactgg
    19081 cacacccacc gtccggcatg cgccgcgtga accacacgcg ccacctttgc gcggccgcgc
    19141 cggagcgatt cggcagacgc gtctgcggcc gcctcggcgc gctcgccgcc gcggtgctgc
    19201 tgtccgcctg cacgctgccg atgctgccgc cttccgacgc gccggtcagc gacgaggtgc
    19261 tggccagccc gagctcggcg ggcaagcgcc tgcgcccgat gccctggcgc ccgctcgacg
    19321 tgcgcgccga ctgccgcttc agtgacgagg ccggctacgt cacacgcatc acgctcgacg
    19381 tggcgcagtc caaggtcagg accttcaacg ccgacgtgga gatcccgcgc cgcggcagct
    19441 gccgcttcca cggcccattc acgcagacac gagaaaagcc gagcgtgcag ctgcgtgccc
    19501 ccgatggctg cacggtggat atcttcgagc agggcaagga cgtcaccgtc ggtttcgcca
    19561 actgcgccag ccgctgcagc cgcggcgcct tcgattacct gtggccgatc atcgtcgatc
    19621 ggaccaacgg ccagtgccac tgagcgcacg gccacacgcg acacgagaac acaccatgag
    19681 ccgatccgat tgggaagtcg tcatcgggct ggaggtccac gcccagctca acaccgccag
    19741 caagatcttc tcgggcgcca gcaccgcctt cggcgccgag cccaaccgcc aggcgagcgc
    19801 ggtggacatc gcgctccccg gcgtgctgcc ggtgctcaac cgcggcgcgg tcgagcgcgc
    19861 catccgcttc ggcctggcga tcggcgccca tgtggccgag aagagcgtgt tcgcgcgcaa
    19921 gaactacttc taccccgacc tccccaaggg ctaccagatc agccagatgg acctgccggt
    19981 ggtggtcggc ggcgcgatca cgatccgcgt cggcgagggc gagtcggggt atgagaagac
    20041 cgtgcgcctg acccgcgccc acctcgagga agacgcgggc aagagcctgc acgaggactt
    20101 ccacggcatg accggcatcg acctcaaccg cgccggcacg ccgctgctcg agatcgtctc
    20161 cgagcccgac atgcgctcgt ccgccgaggc cgtggcctac gcgcgcgcgc tgcacgcgct
    20221 ggtgcgctgg atcgacatct gcgacggcaa catgcaggag ggttccttcc gctgcgacgc
    20281 caacgtctcg gtgcgcagga agggcgcggc cgagttcggc acccggcgcg agatcaagaa
    20341 cctcaactcc ttccgcttcc tgcagcaggc gatcgattac gaggtgcagt ggcagatcga
    20401 caccctcgag gacggcggcc gcgtgcagca ggccaccgtg ctgttcgacc ccgacaccgg
    20461 cgagacgcgc atgatgcgca gcaaggaaga cgcccacgac taccgctact tccccgaccc
    20521 cgacctgctg ccgctgatga tcgcgcccga gtggaaggcg cgcgtgcagg cggagatgcc
    20581 tgaactgcca ggtgcgatga aggcgcgctt catggacgcc tggggccttt cggcctacga
    20641 cgccaccacg ctcaccgcgt cgaaagaggt cgccgacttc taccaggcca cggtgtcggc
    20701 caccggtgcg tcgttggcga cccagttgcc caaactctgc gccaactggg tcatgggcga
    20761 cctcgccgcg cgcatcaaca aggccgagct cgacgtctcc gcgtcgccgg tgtcgcccgc
    20821 acagctcgcc gggctggtcg cgcgcatcgc ggacaatacg atctccaacg ccatcggcaa
    20881 gaaggtgttc gaggcgctgt ggaacggcga gggggcgacg gccgacgaag tcatcgaaag
    20941 acagggcctc aagcaggtga cggacaccgg cgcgatcgag gccatgatcg acgaggtgct
    21001 cgccgccaac cagaagtcgg tggaggagtt ccgcgccggc aaggagaagg ccttcaacgc
    21061 cctggtcggc caggtcatga aggcgagcaa gggcaaggcc agcccggccc aggtcaatga
    21121 gctgctgagg aagaagctcg gcgcctgagc ggggcggggg ccgcgaacgg agggttccac
    21181 gatgtgccag ttgctgggca tgaactgcaa cgtgccgacc gacatctgct tctcgttcgc
    21241 gggcttccgt gcgcgcggcg gactcaccga ccaccaccgc gacggctggg ggatcgcctt
    21301 cttcgagggc cgcggcgtgc gcgtcttcct cgatccggcg ccgagcgcgc attcgccggt
    21361 ggcggagctg gtgaatcgct acccgatccg ctcgctcaac gtcatcgccc acatccgcaa
    21421 ggccacccag ggcgacatcc ggctcgagaa cacccacccc ttccagcgcg agctgtgggg
    21481 gcgctactgg atcttcgccc acaacggcaa cctgaaggag ttcgcacccg cgctctccgg
    21541 gcgcttcctg ccggtcggca gcaccgactc ggagctcgcc ttctgccaca tcctcgacac
    21601 gctggctgcg cgctttccgg agggcaagcc ggcgccggcg gaactgcacg ccgcgctgcg
    21661 cgagctcgcg ctcgggatcg gcagccgcgg cgaattcaac ttcctgctct cggacggcga
    21721 ctggctgttc gcgcactgct cgtcgcggct gtgctacatc gtccggcgtg cgcccttcgc
    21781 cgaggcccac ctcgccgacg aggacctcac ggtggatttc cgccgcctca ccggtccgca
    21841 ggaccgcgtc gcggtgattg ccaccacgcc gctcaccgac aacgaactct ggacgcagat
    21901 cccgccgggc aacctgctcg ctttccgcga tggagagccg gtcgcgcttg gtgaaaccgc
    21961 caccatggcg caggattacc cgcgtcgagg cggcgacaag gtcgggagtg cgtaacagtt
    22021 cctcgcccgc cagcaccgcc gcgcctagat tcaaaatccg tagcccctct gcagccgacc
    22081 gagaaaccct catggactgt cccctgtgcg ccctgccgtc cgaactcacc ctgtgggagg
    22141 acgagcgctg ccgcgtgatc cgcgtggatg acgccgccca tccgggcttc tgccgggtgg
    22201 tatggggcga gcacgtagcc gagatgaccg acctctcgcc cgcagaccgc cgccacctgc
    22261 tcgacgtggt gatggccacc gaggcagcgc tgcgcagcct gctgaacccc gacaagatca
    22321 acctcgccag cttcggcaac atggtgccgc acctgcactg gcacgtgatc ccgcgctacc
    22381 gcgacgaccg ccacttcccc gagtcggtgt ggggcgtcgc gcaacgcgaa ggcgtggccc
    22441 acccggcggc cgacgcggtc gccctcgcac gcgcgatcga cggcgcgctg taccccggcg
    22501 gaccggactg aggaccctcc cccatggact acagccagcc cgcggtctgc ctagccctgc
    22561 tgcagaagct gcacccgacg gacttccgcg ccacgcacgc gagcctggtc cgcatcgtca
    22621 acggcctgct cgacgcctcg ccggcaccca accagcacct cgaggtgctg gaggccgcac
    22681 gcgagaccct cgccttcgtg cagggcgaga tggcgcacgc ctatgcgatc cacccccagc
    22741 ctgcggcacg cagccaggag ggaggtgcgc tcgagcgcgt ggtctcgctg tggaaggcgg
    22801 tggcgcgctc gtacgcgcgc atcgccgact ccgacgcccg cgaaggcacg ctcgaggacc
    22861 agcgcgcgct gctcgcgcag cgcagggtgt tctacgaagg gctcgtgctg gtggagtact
    22921 accgtgccca cctcgagctg ccgccaggcc tctggcatgc ggtgcatgtc gcctacgacg
    22981 acgccgtgcg caacggcctg gcgcaggtgc gcgtgaccga tccgctcaac gaggtctggc
    23041 gggcgcagag tgcgcaggag gcctacatcg gcaccctgct cgtcgagctc gccaatccct
    23101 atggccgcgg cgagcgcgaa ctgaactggg tcgtgcgctg ggcgcagcgc ttcgcgccct
    23161 actgcgcgct cgatgcagac atcgaaggcc acaagcccag cacctacggc atcgacaccg
    23221 acggcgacag cggcctgcgt ccactcgggc tgctcgcaca cacgccctcc gtgctgcgct
    23281 tcgacggcag cgggctcgcc acccagatcc aggcagtgat ggcgcagttc aagcgcggcg
    23341 tcacgcccgc ctcgctcggg ctcggcaacg attgctcggc cagctcgagc gcgcgcctgc
    23401 tgctgtcgct gtaccggccc tggggcctgg ctgcctccgg acggcgcttc ccgcgccggc
    23461 ggaaatccgg tgtgatcgac tttaccggcg actggctcgc gatcggctac gcgatcaagg
    23521 gcgaactctt ccagcagccg gtcaccgagc agcgaccgcg cgctttccgc gacgacatgt
    23581 ccctgctcac cttcggcgaa cgggtggcca ccgtggatgg cagcacctcg gaaagccggc
    23641 ggcgcgaagc gcaggcggcg gacctgggca tggagtgcga gcgctgggag ctcatggacc
    23701 agtcggtggg cggcttccgc ctgcgccgca gcggtgacgg cccacgcctg gaccatcatc
    23761 agctcgtcgg tatccgccca cccgacgccg atcagctgct gatcgccgac ctgagctggc
    23821 tgatgtaccg caacgacggc acgctcgaag tcggcatcaa cgtgctgccg ggagtgccac
    23881 gggtggtcgg cgtgcggcgt acgatcgcgc gcaacggctc ccgcgaaccc ttccaccagg
    23941 cgttcatgct gccgccctcg cccgcactca agaccgccgg cacgctggtc ctgccgcccg
    24001 cctggttcaa gaaggaccgc atcctcgacg ttcaggacgg gcaggagcgc cgacaggtgc
    24061 gcctgctcaa ggtgtcgatg cgcggcgcca acttcgacca gtgcagcttc gagcctgtcg
    24121 agcaggagtt cagcccggcc tgacccgcgc cggcgggaag cgcagcgtga aacggctgcc
    24181 ccgccccggc tcgctctcga tcacgagctc gccgtggtgg cgggtggtga cgtgcttgac
    24241 gatcgccagg ccgagccccg tgccgccggt ctcgcgcgag cgcccgcgat ccacccggta
    24301 gaagcgttcc gtcaggcgcg ggatgtgcac cgcatcaatg ccgatgccgt cgtccgccac
    24361 ccagaactcg ccaccgcccc caccggcgcg ccagccgatc tcgatgtggc caccggccgg
    24421 ggtgtagcgc accgcgttgc ttgcaaggtt ggaaaaggcg ctgcgcaact ccttgtggct
    24481 gccgaggagt tcgccgccgc cctcgagcac caggcgcact tcgtgacgcc cggcggacag
    24541 cagctcgcag tcgcgcacca cgtcgcgcac cagcgcctgg acatccaccc gctcctctgc
    24601 cggcgcaggc gctccggtct cgagcgcgga caaggtcagc agctcctcga tcagccgctg
    24661 catgcgcgag gactgctcgc tggcgagccc caggtactgc accacctcgt cgcgcgtgaa
    24721 atcatcgatg ccgtcgatca gggtctcgag gaagccgcca accacggtca gcggcgtgcg
    24781 cagctcgtgc gaaacgttgg agacgaagtc gcgccgcatc gtctccaggc gctcgagctg
    24841 ggagacgtcg cgcgacagca ccaggcgccg gttgccggcg aaggcgatca cctgcacctg
    24901 caggctgcgc tcgcgccggc gcagcgagcg catcaccagc ggctcggcat actcgtgcgc
    24961 ggcgaggtag cggacgaact cgggctggcg caccaggccg gacagcgcca tgcgcaggtc
    25021 cttgcggcgg tcgaggtcga agtgctgctc cgccatcgga ttcatccact cgatggcgtc
    25081 gtcctcggcc aggtagatca ccccgtcggg catggccagc gcggcctgct ggaagcggcc
    25141 gagctcggcc gacaggcgtt ccttgacctc gcactcgcgc tgcaggcggt cgccgacctc
    25201 ggcgaagacg cgcccccaca agccctcggc ctgcggcacc ggagtgccca cgggctgccg
    25261 cgcccaggtg acgagctggc gcaggttgcg caccagcatg atcgcccagc cgaccagccc
    25321 gaccgccagc agggcgagcg cggcgtcgct gccgcggtag gcggcagcca gtgccgcgag
    25381 gaccatcagc gtccccagcg gcagggcgat gacgagggcg aggtagctga gcgggcggcg
    25441 aatcactggc gcggcgcgag cggaggatca ggacgccgcg gcggcctgcg cggtgtgcac
    25501 cgagaaacgg tagccgctgc cgcgcaccgt ctggatcagc gcatcgtgcg aactgggctc
    25561 gagcgcgcag cgcaggcggc ggatgtgcac atcgacggtg cgctcctcga cgaacacgtg
    25621 gtcgccccag acctggtcga gcagttgcgc gcgcgagtgc acgcgctcgg ggtgggtcat
    25681 caggaagtgc agcaggcgga actcggtggg accgagcgcg agcgcggtct cgcccgcgct
    25741 gacgcggtgg gtggcggggt cgaggcgcag gccgccgagt tcgaccacgt cctcggtggt
    25801 ctgcggcgcg cgccggcgca gcaccgcctt gatgcgcgcg accagctcgc gcggactgaa
    25861 gggcttggtg acgtagtcgt cggcgccgat ctcgagcgcg gtgaccttgt cctgctcctc
    25921 gccgcgcgcc gtcagcatga tgatcgggat gtcgctggtg cgttcgtccg cgcgcagccg
    25981 gcgcgcgaac tcgacgcccg acgcgccggg cagcatccag tccagcagca ccagatcagg
    26041 tagcgcttcg cgcacgatgc gctgcgcgct ctcggcgtca ttggcgcgca ctacgtgatg
    26101 gccggcgcgg gcgagattcg ccgcgatcag ttcctggatc gccggctcgt cttccacgag
    26161 cagtatgttc gctggcatgc ctgtgctccc tgaaaaatgc ccgtgaagtg tattgcagct
    26221 ccttgacgct ttgatgacac gtcatcgaag cgcaatgcgc aataccggga catcgcggtc
    26281 cgggacgcgg gacggacaaa agccggcccg cgggaaccgc cactcaggcc ggctgcttgc
    26341 gtgctccccg ccggagaggg tgcggcacaa gagggtggga gcacaagccc aaggggctca
    26401 gcttccctgc cagagcgcgt cgaccgtccg cggcgccagc gccagcagga cccggcgccg
    26461 atagccgacg ccggtgacgg tggtcttgag gacgttcgac gtcttgcgca ccagctgggc
    26521 cagggcctcg gcggcggcgc catcccagcc ccctcccacg agctcgtccg tgggcacgag
    26581 caggggggcg gagttggacc cggtgatcgc caccctcagg ccggcgatgc ggtctccgtc
    26641 acggcgcagg gcgacggcga cgcccgcgag cgggaaatcg acggcatcgc ggatgcgcgc
    26701 cttggcgtag gcggccgtcc agccgtcggc gggagggacc tccaccgccg ccaccagttc
    26761 gccccgattc aaggcgaggt gcccggcacc gtcttcgcgg aacaactccg ccaccgcgac
    26821 gctgcgcctg cccgtcgggc cgacgagttc ggcgcgggcg tccagcacca tcagtgccgg
    26881 ggcgacgtcg ccgtggtagg tcgcatagca gcggtcgttc ttgacgatga cgtggcactt
    26941 gtcgccccga tacttcaggc agtagccgtt tccggcacgc caccactcgc tctggttgta
    27001 gaagatgcag cgtgtgtcct ggcacaggtt gccgcccagg gtggccgcag cgcgatgggt
    27061 cggccccgcc accgcttcgg cggcctggga caacgcgggc cagcccgcac ggacgagcgc
    27121 gtgctcggcg accgcctcca gggtggcacc ggcgccgatg cgcaggctgc cgtcggcgag
    27181 ggtggagatc gtgcccaggc catcgatgcc gcccaggtcg acgaggactt cgggctgtcc
    27241 caggccacgg cgaaggttgg gcagcaggtc ggtgccggca gccaggggca cggcgccgtc
    27301 ggcgtccagg gcggccaccg catcggccag ggtggcgggg cgatgggtgc ggaaatcggc
    27361 gaggatgttc atgctgcctc cttggcgtcg agcagttcgg tgatgcggtc ggggctgagc
    27421 gggaactcgg tggcgcgcac cccgaccgct tcgtagaccg cctcctggac ggcgggaagg
    27481 aagccggcca gcatgccctc cgaagcctcc ttggcgccga acgggccgtt ggggtcgagg
    27541 ctctcgacga tgatcacctc gatgtcgggg ctctccatca tggtggggac gcggtaatcc
    27601 aggatgttgc cgtgcaacat cctgcccttg tcatagacga tctcttccga cagggcctgg
    27661 cccatgccca tccacacccc gccttgcgtc tgcccttcca ccgcgagggg gttgagcgcc
    27721 ttgcccacat cgaccgcaac ccagaccttg tgcgcggtga ccttgccggt gatctcgtcc
    27781 accgacgcct ccaccacctg ggcggcatag cagaagccca tggtggcgcc gatcgcgctg
    27841 ccgcggatgc gcttgtcgcc ctggaactcg gtcgggcagg tgaaggtgcc cttcacggtg
    27901 atggtgccgg aatcgaccat cgcggccttg accacctcct ggaaggtcag cccggggtcc
    27961 tggctgcccg agaccatgaa gagctcgtcg atgacctcga tgtcttcctc gcgggcgtcg
    28021 agcttcttcg ccgccgcctt gaccaggatg cccttgagct cctcggcggc ggagatggag
    28081 gcgttgccga ccatgaaggt gacgcgcgac gaatacgagc cgttgtcctt gggcgtcagc
    28141 gcgctgtcgg cggagatcac ccggatgcgg tcgaggcgca cgcccagcac ctcggcggcc
    28201 acctgcgagg ccatggtgtt ggaaccctgg ccgatatcgg cggcgccggt cagcagggtg
    28261 atgccgccgt cgaagtcgag cttcaggttg acggtggcgt gcggctcgcc ggtccagtgc
    28321 ttgggcgtcg aggtgcccga gacgaaatgc gacagcgcga tgcccaggcc gcgccccttg
    28381 ggcagcctgc ccttgcgctc ctcccagccc gaggccgcct tgaccttctc caggcactcc
    28441 ggcacgccat agctcatcac cctctgggca tacatggtga cgtaggggat ctccggcagc
    28501 atgttgagct ggcggatgcg cagcgagtcg atgccgagct cctcggccat ctcggtcagc
    28561 agcgcctcga aggcggcgcg ggtgtccacg gtgccgtggc cgcgcatcgc gccgctcggc
    28621 ggcaggttgg tatagacgcg ccaggcgtcg tgcttgatcg ccgggatgtg gtacagcccg
    28681 tgcatcagcg cgccgctgta gagaatggtg atgatgccgt agccggcata cgcgccgccg
    28741 gcctgggtgg cctcgagcgc gagggcggcg atcttgccgt ccttcttgag gccgagcttc
    28801 atcttcacct cggtccacgg cctgccgcga tgcgcgatga aggtctcctc gcgggtctgc
    28861 accaggcgga ccgtgccctt ggccttgtgc gcgagcagcg cggcgatgat ctcgaagtgc
    28921 agggtctcgg tgcgcgcacc gaagccgcca ccgaggaagg gcttgatcac gcgaatgcgg
    28981 gccgagtcca tctgcaggca ggccgccacc ttgaggtgca cgtagtaggg cacctgggtg
    29041 gtggtgttca gcgtcagcat gtcgcgcacc gggtcgtact cggccagggt ggcgttgagc
    29101 tccatgtgga cgtggttgac cccggcgaag gtgtaggtct tctcgcggat caggtcggcc
    29161 tcggcgaagg ccgcggcgac gtcgccgaac tcggcatgca cctcgcgcag cacgttgtcg
    29221 ggcttgtcgt cgtggatcgc gaccgcgccc gccttgcgcg ccgccttggg ggtgaagtac
    29281 gcgggcagga cctcgtactc gacgcggatc aggccgagcg ccctctccgc ggtcgcctcg
    29341 tcgatcgcgg cgactgccgc caccggatcg ccgcgatagc gcaccttctc gcgcgcgagc
    29401 ggatattcgt tctcggcgat cggcagcacg ccgtagggca ccggggtctc ggcgccggtg
    29461 cacaccgcga acacgccctc gagcgcctcg gccgccgcgg tgtcgatgga gaggatgcgg
    29521 gcgtgtgcgt ggggcgagcg caggatgcgc ccgaccatcg cgtcgggggc ggcgatgtcc
    29581 gccgtgtatt tggccttgcc ggtgaccttc tccaccccgt ccaccagcgg cgtgcgggca
    29641 ccgaccgtgc cattcttcgg aaacctgggg ttcatttcgc ctcctccgcg caccgctgcg
    29701 ccgccgccgc ggcctccacg gactcgatga tcttcacgta gccggtgcag cggcacaggt
    29761 tgccggccag cgccgtcttg atgtcctcgc gcgaggggtc ggggttcttg cgcagcagcg
    29821 cttcggacgc catcagcatg cccggcgtgc agaagccgca ctgggtgccc agcttctcgt
    29881 ggaatgcggc ctgcagccgg gagagcatgc cgtgggtcga cagcgactcg acggtctcga
    29941 ccttcctgcc ggcgacctgg tgcgccaggg tggaacaggc gaggcggggg cggtcgtcca
    30001 ccaggacggt gcaggcgccg cattcaccgc catcgcagcc ctgcttggta ccggtgaggc
    30061 cgaccgcctc gcgcaggtaa tccagcagca gcatgttgtc ggggacgagg tcctcacgga
    30121 gacgcccgtt gagggtcagg cgaaggatgt tcttcaagat tcggctccta atcccgcgcg
    30181 agcggtcgag gtttcacggt ctggttggta aagccgggtc agcaggtcga tcagcgtggc
    30241 gcgctcagca tcgtcgaggc gggccgagaa cgcccggtcc tggcgcgtca ccgcgtcctc
    30301 gatgcgttgc agcgcctgcg cgccggtcgg cgtcatgtgc agccgatagc gccggcgatc
    30361 ggtcggagag gtgtcacgga cgatgagccc cttctcctcg agccgatcga cgaccttgac
    30421 gatcgaggag cggtccacgt ccatggcgac ggcgagcgcg ctctggctca gccccgggtt
    30481 gctgccgatc gcctggagca tgccgtagag cccgggagtg attccctcct ccgcgccgac
    30541 tgcctgggcg aagtgcctga atgcggcgag ctgcgcacag cgcaggtgaa aaccgagttc
    30601 gtccgccatc gggccacgga gaaccatcgc tcgctcgcca ggaatcggca cttccaggga
    30661 catgctattg gcgcctcaaa ttgtttgtgt tccaattgtt gctccaacaa cgcttttctg
    30721 caaccgaatt gttttgccga tcgacaggat ggccgacgcc cgtcacgcgc cctctccccc
    30781 acacgcggaa acgccccatg aacgaaccct cgacgccagc tgcaccgctt cttccggcaa
    30841 tgcccgatgc cgagtgcccc gtgcgcgaat gcttcgggct cgacagcgac atgcgggtac
    30901 cggccttcag caaggccagc gaacatgttc cgcagcgcga cgacacctac cgcttcgacc
    30961 ccgacaccac gctggccatc ctggcgggct tcgcgtacaa ccggcgggtc atgatccagg
    31021 gctatcacgg caccggaaaa tcgacccaca tcgagcaggt ggccgcacgc ctgaactggc
    31081 catgcgtgcg catcaacctc gacagccacg tcagccgcat cgacctgatc ggcaaggacg
    31141 ccatcgtgct gcgcgacggc aagcaggtga ccgagttccg cgagggcatc ctgccctggg
    31201 ccgtgcaaca tgcgtgcgcg ctggtcttcg acgaatacga cgccggccga cccgacgtga
    31261 tgttcgtgat ccagcgcgtg ctggaggtcg agggccggct cacgctgctc gaccagtcgc
    31321 gggtgatccg cccgcacccg gcgtttcgcc tgttcgccac cgcaaacacc gtgggcctgg
    31381 gcgacagcac cgggctctat cacggcaccc agcagatcaa ccaagcgcag atggaccgct
    31441 ggaacatcgt cgccaccctg aactacctcg agcacgatgc cgaggtgcag atggtcgtcg
    31501 ccaagctcac cgcctacgac acgaaggcgg ggcgtgcgcg cgtcggcgcg atggtgacgc
    31561 tggccgacct cacccgccgc ggcttcatcg agggcgacct ctccaccgtc atgtcaccgc
    31621 gcaccgtcct gagctgggcc gagaacgcgt tgatcttcgg ggatctccgc ttcgccttcc
    31681 gggtcagctt cctgaaccgc tgcgacgaga tcgagcgcgt gctcgtggcc gagtactacc
    31741 agcgctgctt cggcgaggag ctgatcgacc cgcgcgcgcg cgcgggctga tcgccggatc
    31801 atggcaggcg aacgctcgcg cgcccgggca ctgcggggaa ccggcaacac ggctgcgttc
    31861 ttgcaggcgc tcgacagcac cctgcgcgcg atcgccgggc gcgcgggcgg cgcggccaac
    31921 cggcccgacg tgggtgggtt cgagggcgcc gcgctgccgc ccatcctgac gagcgcggag
    31981 atcgtccggc tgcgcggccg cgccgacgcg ctggccttgc gcctgcgcca tcacgacgcg
    32041 cgcctgcatg ccctgcagga gctgcagggc gagcaggcac gagcggcata cgaggcgatc
    32101 gcacaggcac gcgtcgaagc cttggcgacg ggccgaatgc ccggagtcga cgcaaacatc
    32161 gccgccctca tcgaccagca atgccgggac aggcggctcg atcgcgcaag cagccgcgaa
    32221 caggctcctc tggccgaggc cctgcacatc ctcgcccgcg aacgttttct tggcgcacca
    32281 ccgccccctg ccgcacgggc catggccgag ctgtggcgac cctacttcga cgcccacgtc
    32341 gccccgcgcc tcgatgaact gcgcgaacac ctgcgcgacg agccggcctt cgccgccgga
    32401 ctgcgggagc tgatccgggc gctcggtctg gagggccccg caagcgaagc gcgggagcag
    32461 cgcaagctcg cccgccgcga ggccgaggcg ggtgaggaag aagcccccgg accgtcgcgg
    32521 gcgggaaccc ctgcagcaag cgatgcggag ccctcgcggc gtcagagcgc cgccggccgg
    32581 gaacaggatg gagaggccgc ggggatcgac ccgtccgccg aagcggagca cgcttgcgca
    32641 gcgcggggcg aaccggtgcg cgacacccct tccgcacgga ggcagggcgc ctcctaccat
    32701 gcctacacca ccgccttcga cgacatcgca gacgcggacg agctgtgcga cgcttccgag
    32761 ctggcccttc tgcgcgcccg actggatcgc gagctgacgc gcctgcccgc gctcgtcggc
    32821 cggctcgcca ggcgactgca gcaccgcctg ctggcgagcc gcctgcacga ctgggcgtcc
    32881 gatctcgagg agggctggct cgatcccgcc cggctcgacc gcctagtcgt cagccccgat
    32941 cgcggactgc cgttccggat ggaaaaggcg gccgccttgc gagacacggt cgtctgcctg
    33001 ctgctcgaca actccagctc gatgcgcggt cacccgcttg ccgtcgcggc gatgagcgcc
    33061 gacatcctgg cacgcacgct ggagcgctgc gggatcaagg tcgagatcct gggattcacg
    33121 acgcggagct ggaagggagg aagggcccgc gagcgctggc ttcatgacgg cgcccccgca
    33181 gctccgggac ggctggccga gctacgccac atcatctaca aggctgcgga cacgccctgg
    33241 cggcgggcgc gcaggaacct ggggctgatg ctgcgcgacg gcctccccaa ggagaacatc
    33301 gacggcgagg cgctcctctg ggcccatcgc cgcctgctcg cccgtcccga aggacgccgc
    33361 atcctcgtcg tcgtgtcgga cggcgcgccc gccgacggcg ccaccctcgc ggcgaactcg
    33421 gccgattatc tcgagcgcca cctccacgac gtgatcgcct cgatcgagcg gcgctcgccg
    33481 gtggaactgc tcgcgatcgg catcggccac gacgtcaccc gccactaccg ccgcgcggtg
    33541 acgctgcggg atgccgacga gctcgggtcc gccttgctgg agcagttgtc gcgactcttc
    33601 gacgagcgcg cctgagcgct gcacgccgga ccgcccgctc gcgtgcagac ccggcgggcg
    33661 cccgcgcccg cgtcggaacg gctcgccggc gattcgggta tgattgggcc ccctgcaagc
    33721 ggaccgacgc catggccgga ctcgacgaaa acaccccgac gcccaccgac atcatcgtcc
    33781 atcgcgaccg caagacgctc gaggtcgcct tcgacgacgg cagccgcttc gagctgccgt
    33841 tcgagttcct gcgcgtgtat tcgccctcgg ccgaggtgcg cggccacggc ccggggcagg
    33901 agaccctgca gcagggcaag cgcgatgtgg acatcgtgga cctcgcgccc gtcggcaact
    33961 acgcgatcaa gcccaccttc tccgatggcc acgacagcgg cctgtactcc tgggactacc
    34021 tgtttgcgat cgggcacaac caggaagagc tgtggaacaa ctatcttgag gccctggagc
    34081 gcgcgggcgg cacccgcgac ccgtccaagg tcccgccacc gccgcccaag ggcggctgcg
    34141 gccaccatca ctgagcagat catgagcgac aagacgaccc acttcggctt ccagaccgtg
    34201 gccgaggagc tgaaggaaaa gaaggtcgcc gaggtgtttt cctcggtggc gcagaagtac
    34261 gacgtgatga acgacctcat gtcgttcggc ctgcaccggc tgtggaagca cttcaccatc
    34321 caggtctccg gcgtgcgcga aggcgaccgc gtgctcgacg tggccggcgg caccgccgac
    34381 ctctcgctcg ccttcgcgaa gaaggtcgga cgcagcggcc aggtctggct caccgacatc
    34441 aaccacgcga tgctggcgcg cggccgcgac cgcatggtcg accatggctt cgcgatgccc
    34501 gccgcgcaat gcaacgccga gaagctgccc ttccccgacg actggttcga ctgcgtcacc
    34561 gtggccttcg ggctacgcaa catgacccac aaggacgtcg cgctggccga gatgcgtcgc
    34621 gtgctgcgcc ccggcggccg tctgctcgtg ctggagttct cgcgcgtgtg gaagccgctg
    34681 tcgccgttgt acgatctcta ctccttcaag ctgctgccgt ggatgggaga gaaggtcgcc
    34741 aacgacgccg agagctaccg ctacctggcc gaatccatcc gcatgcaccc gggacaggaa
    34801 gaattgaagg caatgatgga acaagccggc ctgtcgcggg tcgactactt caacctgagt
    34861 gccggggtgg ttgccctgca ccgcggttac aagatctgaa ccaggagacc ccgacagatg
    34921 aagcagttct tcctcaccct gatcgtcgcc gtgatgtcct tcggcttcgt cgccaccgaa
    34981 gccgaagcca agcgcctcgg cggcggcagc agcttcggca tgcagcgcca ggctacaccg
    35041 ccagcgcaac gccagccctc ggcgacgcag cagcagacgc ccgccgccgg cgcagccacc
    35101 gctgccgcac aacccaagcg ctcgtggatg gggccgatcg cgggcctggc cgcggggctc
    35161 ggcctcgccg cgctgttctc cgcgctcggc ctcggcgaag gcttcgccaa cttcgtcatg
    35221 atcctgctgc tcgccgcagc ggccttcttc gtcttccgcc tgatcttccg gcgcggagcg
    35281 aacgcggcca cacagcagcc cacccgtgac ctgcagtacg caggcgcgcc tgccggtgct
    35341 gcgcagcagg cgcgtccgca gcagtttgaa gccgctcgtc ccctcggtgg cggcagcgca
    35401 cccgcgcaga gcggcctcga caaggcgcgc gccggcggct tcgataccga aggcttcgcc
    35461 cgccaggcca agctcaactt catccgcctg caggctgcca acgacgccgg caacctcgac
    35521 gatctgcgcg agttcaccac cccggaggtg ttcgccgagt tgtgcatgca actcaacgag
    35581 cgcaagggtg ccgagcagcg caccgacgtg gtcgagctca atgccgaggt gatcgacgtc
    35641 gccgaagaga acgaccgcta cgtcgtcagc gtccgcttca gcggcctgct gcgcgagcag
    35701 gcggacgccg cgccggaagc cttcgacgag atctggcacc tgagcaagcc gctcgcaggc
    35761 agcgctggct ggctgatcgc cggcatccag caatctcagt aagccgacag gcgggcacgc
    35821 cccgcgtgcc ccggtcttgc cgcgggcctg cccgtgtctc cctggaggca ccggcaggcc
    35881 cgccgttttt ggagtacggc atccgagaca aggcctcctc ggctgcgtat ccttggaaac
    35941 cgcccgccac tctccggagc cctccaccat gatctccagc ctcttcctga cggccaccaa
    36001 ccacctgctc gcgcaggccg gatgggcccg ccagcgcctg cagccgcatg ccggacgcac
    36061 ggcgcggctg gtgctcagcc cggtggccga gatcgacttt tccgttgcca acgatggcca
    36121 gctcgccgag tggagcggtg aggaagcgcc cgaggtgagc cttcgcctgg cggtggccga
    36181 cctgccccgg ctgctggtgg acgggctgga gacggcgatg cggcacgtgc gcatcgaagg
    36241 caacgccgag ttcgccgagg cgctcggctt cgtctttcgt cacctgcgct gggatgccga
    36301 ggaggacctg tcgcggctct tcggcgacat cgcggcccat cggctggtgg aaggcgggcg
    36361 caaggcgatc gacgagggcc gccgcggcct ggagcgggcg agcggaaacg tggccgaata
    36421 cctcaccgag gaatccaccc tgctcgtccc gcgccgggcc ctgcccgcat tcgccgaaga
    36481 ggtggtcgca ttgcgtgacg ctgtggcgcg cctggacaag cgcgtggcga ggctggaaaa
    36541 acggcgctga cgagcgtgcg gtgcggcgcc cgatccgcta agcaggagcc ccacatcttg
    36601 cccgatcgtg tgcacccgcg ccgagcatgc gcgaaaaaaa agcagctcgg tacgagctgc
    36661 tttcgggata tcgatcacac cggctgcccg gtgcaatcag gtctcagtgg ccgcgcttgc
    36721 gcaggcgctg gatcgcggcg agctgcgcca ccgcttccat gagctcggcc tgggccttgg
    36781 catagtccag acgcgcggtc tggttcgcca tggcttcctc ggccttgcgc ttggcttcga
    36841 gcgccttcgc ctcatcgagg tccttgccgc ggatcgcggt gtcggcgagc accgtcacca
    36901 gacccggttg aacctccagc aggccgcccg cgacgaagat cagttcctct tcggtcgcgt
    36961 tctgggcacg cacgcgcacg gcacccggct tgatccgggt catcagcggc atgtggccgg
    37021 gcaggatgcc cagctcgccc gcttcgcccg gcaatgcgac aaactcggcc agcccggaga
    37081 agatctgctc ttccgcgctg acgatgtcga catgaaccgt catagccatt gtgtttcccc
    37141 ttgatgtccc gcgcgccgct tgcacgacgc gcgggcgacc tcgttactgg agcttcttcg
    37201 ccttctcgat ggcctcgtcg atgccgccga ccatgtagaa ggcctgttcc ggcaggctgt
    37261 cgagctcacc ggaaacgatc atcttgaagc ccttgatcgt gtccttcagc gagacgtact
    37321 tgcccggcga gccggtgaac acttccgcga cgtggaaggg ctgcgacagg aagcgctgga
    37381 tcttgcgcgc gcgagccacg gcgagcttgt cttccggcga cagttcgtcc atgcccagaa
    37441 tcgcgatgat gtcgcgcagt tccttgtact tctgcagcgt catctgaacc tgacgcgcca
    37501 cgttgtagtg ctcttcgccc acgaccagcg gatcgagctg gcgcgaggtg gagtcgagcg
    37561 gatcgacggc cgggtagata cccagcgcgg cgatgtcacg cgacagcacg acggtggagt
    37621 cgaggtgcag gaaggtggtg gcgggcgacg ggtcggtcag gtcgtccgcg ggcacataca
    37681 cggcctggat cgacgtgatg gaacccacct tggtggaggt gatgcgctcc tgcaggcggc
    37741 ccatttcttc ggccagcgtc ggctggtagc ccaccgcgga cggcatacga cccagcagcg
    37801 cggacacttc ggtacctgcc agggtgtagc gatagatgtt atccacgaag aacaggatgt
    37861 cgcggccttc gtcacggaag cgctcggcca tggtcaggcc ggtcagcgcg acgcgcagac
    37921 ggttgcccgg gggctcgttc atctggccga acaccatcgc gaccttgtcg agaacgttgg
    37981 agtccttcat ctcgtggtag aagtcgttgc cctcacgggt acgctcaccc acgccagcga
    38041 acaccgacag acccgagtgc tgcttcgcga tgttgttgat cagctccatc atgttcacgg
    38101 tcttgccgac accggcgcca ccgaacaggc ccaccttgcc gcccttggcg aacgggcaga
    38161 tcaggtcgat aaccttgatg ccggtctcga ggagctccac ggacggagac agctcgtcga
    38221 acttcggcgc cttctggtga atggcgcgca gctcgtcggt ctcgatcggg ccggcgtcgt
    38281 cgatcggacg acccagcacg tccatgatgc ggccgagcgt gcccatgccg accggaacgg
    38341 agatcggctt gccggtaccg gagaccttca ttccgcggcg caggccgtcg gaggagccca
    38401 gcgcaatggt acgcaccacg ccatcaccga gctgctgctg gacctcgaag gtcaggccag
    38461 cttcggcgaa ggagtcggca gcgtcctcga gcttcagggc gtcatacacc ttgggcatcg
    38521 aatcgcgcgg gaactggatg tccaccacgg cgccgatgca ctgaacgatc gtaccttgac
    38581 tcatcgtcat atccttaatt caataatgcc ttacaccgcg gcggcgccgc cgacgatttc
    38641 cgacagctcc ttggtgatcg cggcctgacg ggtcttgttg tagaccagtt gcagctcgcc
    38701 gatcacgttc ttggcattgt cggacgcggc cttcatcgcc accatgcgcg cactctgttc
    38761 ggatgccatg ttctcggcca cagcctggta caccagcgcc tcgacgtagc gcaccagcaa
    38821 ttcgtcgatg acgacctgcg ggtccggctc gtagagatag tcccaggagc tctccggcgt
    38881 tcccagctgc tcgccggtga gcggcagcag ctgttcgagc accggctcct gtttcatcgt
    38941 gttgatgaag cgcgtgtatg ccacgtaaac cgcgtcgagc tcgtcgttct ggaacgcatc
    39001 gagcatgacc ttgaccggac cgatcaactt ttccaagtgc ggcgtgtcac cgagctgggt
    39061 gacgttcgac accaccttgg cgcccatgcg ctgcatgaag ccgagaccct tgttgccgat
    39121 gcagcaggca cggatctcgg tcacacccga ggactcccag tccttcatgg cgttgagcgc
    39181 aacacgctgg acgttggtgt tgaggccacc gcacaaaccc ttgtcggtgg tcaccaggat
    39241 caggcccacc cgcttgacct ggtccttgcg gaccaggaag gggtgcttgt agtcggtcac
    39301 attggcctgg gacaggttcg cggcgagtcg gcggatcttt tcggcaaagg ggcgggcgct
    39361 acgcatccga tcctgcgcct tgcgcatctt ggatgcagcc accatctcca tggccttggt
    39421 gatcttgcgc gtgttttgca cgctcttgat cttggtacgg atttccttac cgctagccat
    39481 tttccgtctc cctcgccggc cttaggccca gctcttcttg aactcggcga tcgcggcagc
    39541 cagggtcttt tcgccgtcgg cgtccagttc cttcttgctc aggatcgagg agaccagagc
    39601 ggactgcttg gtcttgacga actggatcat ggcggcctcg aaagccagca cgcgacccac
    39661 gtcgacatcg tcgaagtagc cgttgttcac cgcgtacagc acgatggcca tgtcggcaat
    39721 cgacatcggc gagtactggg cctgcttcat cagttcggtg acgcggcggc cgcgctcgag
    39781 ctgcttgcgg gtggcgtcgt ccaggtcgga ggcgaactgg gcgaaggcgg cgagctcgcg
    39841 atactgcgcg aggtcggtac ggataccgcc ggagagcttc ttgacgacct tggtctgggc
    39901 ggcaccaccg acgcgggaca ccgagatacc ggcgttgatc gcgggacgga taccggcgtt
    39961 gaacaggtcg gtctcaagga agatctggcc gtcggtaatc gagatcacgt tggtcggaac
    40021 gaacgcggac acgtcgccgg cctgggtctc gatgaccggc agtgcggtca gcgaaccggt
    40081 cttgcccttg acttcgccgt tggtgaactt ctcgacgtag tcctcgttga cacgcgcagc
    40141 gcgctcgagc agacgggagt gcaggtagaa cacgtcgccc gggtaggctt cacggcccgg
    40201 cggacggcgc agcagcagcg aaacctggcg gtaggcccag gcctgcttgg tgaggtcgtc
    40261 atagacgatc agcgcgtcca tgccgcggtc gcggaagtac tcgcccatgg tgcagccggc
    40321 gtaggcggcc aggtactgca tggcggccga ttccgacgcg gtggcggcga cgacgatggt
    40381 gtattccatc gcgccgttct cttcgagctt gcgcacgacg ttggcgacgg tcgaggcctt
    40441 ctggccgatg gccacgtaca cgcagtacat gtcctggccc ttctggttga tgatcgcgtc
    40501 gaccgcgacg gcggtcttgc cggtctggcg gtcgccgatg atcaactcgc gctggccacg
    40561 gccgatcggc accatcgagt cgaccgactt caggccggtc tgcaccggct gcgagacgga
    40621 cttacgggcg atgacgcccg gcgcgacctt ctcgatcttg tcggtgagct tcgcgttgat
    40681 cgggcccttg ccgtcgatcg gctggccgag cgcattcacg acgcggccga tcagctcggg
    40741 gccgacgggc acttcgagaa tgcggccggt ggccttgacg gtgtcgcctt cggtgatgtg
    40801 ctcgtactcg ccgagcacca ccgcgcccac ggagtcacgc tcgaggttca gagccatgcc
    40861 gtaggtattg ccggggaatt ccagcatttc gccctgcatg acgtcggtga gaccgtggac
    40921 gcggcagata ccgtcggtga cggagactac cgtgccctcg ttgcgcgacg tggcggcgag
    40981 ctgcaggttc tgaatccggc tcttaatcag atcactgatt tcagaggggt tgagttgcat
    41041 tttgcgataa ctcctagttc ttgagcgcag cggccatgtt cgcgagcttg ccgcggaccg
    41101 aggcgtcgat gacttcgtcg ccgacggcga tgcggacccc accgatcagt tcggggtcga
    41161 tgctgaccgt gatattgacg gcggccttga agcgggcttc gaggtcggcc ttcaacgcgg
    41221 ccagggcggc atcgtcgagc gggaaggcag aggcgatttg cgcctcgcgg acgccttcgt
    41281 gttcgttctt gagagcaacg aacaggtcac ggatctccgg aagcacctgc agacgttcgt
    41341 tttccacgag gacgcggacg aagttctgct gttcggcggt caggtcaccc gaaacgccca
    41401 gaacgagctg gtagagctgc tcggcggaca ggttgggatc gttgaagcac gccttcatgc
    41461 cggaatcggc cgccacgagg gcaagccgat ccagcgcttc cgaccaaggc cccagcgcac
    41521 ctgccccgcg ggccagctcg aaggcggcat ccgcataggg gcgcgcgatg gtgacgttct
    41581 cggccatgac ttattgcagt tcctgtttca ggttggcaag cagcttcgca tgcaccttgg
    41641 cgtcgatctc gcggcgcagg atcttttccg cgccggcgac ggccagatgg gcgacctggt
    41701 cgcgcagggc ttccttggca cgctgcgtgg cggcaccggc ttcgtgctcg gcggcctcgc
    41761 gggcggcggc aatgatgcgg ccggcttcgg cgcgggcctc gtcgatcagc tggctcgcct
    41821 gcttttcagc ggaggtccgc acatcacccg cggattcgcg ggccttgcgc agttcctcga
    41881 cgaccttctt ctcggcgagc gccagatcag ccttggcctt gtccgcagct gccagcccgt
    41941 ctgcgatctt gttcgcacgc tcgtccagcg ccttcacgat gggcggccac acgaatttca
    42001 tcgtgaacca cgccagaatg aagaacacaa cgagctgggc tatcagggtt gcgttcaaat
    42061 tcacggttct tggccctcag gttggttcaa aaaaggatga actcgaaccg atcagagctg
    42121 gaacgggttg gcgaaggcga acatcatggc gataccgaca ccgatcagga acgcggcgtc
    42181 gatcaggccg gccagcagga acatcttggt ctgcagggcg ttcatcagct cgggctgacg
    42241 agcggacgcc tcgaggtact tggaacccat gatgccgata ccgatacaag caccgatcgc
    42301 acccagaccg atgatcagac cagcagccag agcaacaaaa cccagaacgt tttccatgac
    42361 gactccttag tggggaagtg agtttaaaaa ccaggtacta cgctgaaggt gaaaccgaaa
    42421 ctcttagtgg ctctcgtgcg cctgaccgac atacaccaag gtcagcatca tgaagatgaa
    42481 ggcctggagc gtaatgatca ggatgtggaa gatcgcccag atcgagccgg cgatcacgtg
    42541 gccgaggaag ccgaacacgg tggcggtgct gcccagcagc gcgatcagga tgaagatcag
    42601 ctcgccggcg tacatgttgc cgaacagtcg catgccgtgc gagacggtct tggcgacgaa
    42661 ctcgatgatc tgcatcgcga agttgatcgg atacagcagc ggatggctgc cgaagggggc
    42721 ggtgaagagc tcgtgcaccc agccgccgac acccttgatc ttgatgttgt agtagaggca
    42781 cagcaggagc acgccggtgg acatgccgag cgtggcggac aggtcggcgg tggcaacgac
    42841 acgcatgtag gcgtgggccg gatcgccgcc acctgcggcg tacatgcctt cccagatgcg
    42901 cggcagcaga tcgaccggca gcaggtccat cgcgttcatc aggaagatcc acacgaacac
    42961 ggtcagtgcg agcggagcga cgaagcggcg cgactcggcg ctatggacga tgcccttggc
    43021 ctggtctgcc accatgtcga cgaggatctc gacgatgccc tggaagcgcc ccgggacgcc
    43081 cgaggtggcc ttgcgcgcgg caagccagag caggaagacg gttagtgcac cgatcacgac
    43141 cgaatagaac atcgaatcga ggttgatgac actccagtcg atgatgtttt cttgcgcgtg
    43201 tccggtgttg ttgaggtgcg tcaggtggtg aatgacgtac tcggatgcgg tgggggcgtg
    43261 cccttctgta gccatggtca ggtctttacc aaaaatgcaa acaaattcgc cttaagcgcc
    43321 aggatgagac cgaccagcat gcccccccaa tggaggtcag gatagacggc ccacaccagc
    43381 accaacaatc ccacgatcga ggcgatcttg aggaactcgc ctgcgacgaa ggcggtcaca
    43441 gtcgccgtac cagtcttgcg cgtgatcgcc gcgaggcgta acgcaaaaag accgctgggc
    43501 aacacgcatg ccagccctgc ccctgcggcg gagatcgcac cgctcactcc gaacagcgcc
    43561 gccgagaggc ccgctgcgac gagtgtcgcg atcatctgca gtatgacagc tttaagcatc
    43621 cggtgttatc gcatgcgcgt cgatgacgct cgcgaccgcc tgaaatcccg cggatggtag
    43681 gggttaaccg cagcaaagtc aaaccttgga tgcgctgcag caagggaaaa cgcattgctg
    43741 ttgtgtctta tagaagacat aacatagcaa gcctcggcgg atgtgagctt cccgcccgca
    43801 aggaggggcg ggcgagcggc cgaattcggc gcggcaagtg gctgtggagg cgcgataacc
    43861 ggcgacccgg cgcgcatgcg tcgacgcaag gccggaaggc gtcagcgcaa ccttccgagt
    43921 acgccgtcga gctggtcgag gctgccgaac cggatcgtga gttcgcccgc gcccttcttg
    43981 ttggccttga tcttgaccgt ggcgccgatc gcgtccgcga tctcctcctc cagccgcaac
    44041 aggtcgcgat cgggcggggg cgcgggcttc ttctgccgcg ggttgaggat ctgctgcacc
    44101 aggcgctcgg tatcgcgcac cgagagctgg cgcgcggcca cctgattgcc gagctggatc
    44161 tggctggcac cgtcgagcgg cagcagggcg cgtgcatgcc ccatgtcgag gtcgcccgcc
    44221 atcagcagct cctgcaccgg cttggcgagg ttgagcaggc gcagcaggtt cgaggccgcc
    44281 ggacgcgagc ggccgacggc gtcggcggcc tgctggtggg tcatgtcgaa ctcgtcgatc
    44341 aggcgctgga tgccgccggc ctcctcgagc ggattgaggt cctcgcgctg gatgttctcg
    44401 atcagcgaca tcgccagcgc ggcttcgtcg gggatctcgc gcaccaggca gggcacctcg
    44461 gccagcccgg cgatctgcgc cgcgcgccag cgccgttcgc cggcgatgat ctcgaaggcg
    44521 tcctcgccca ccggccgcac catgatcggc tgcatcacgc cctgggcctt gatcgaggcc
    44581 gccagttcct ccagcgaacc cggatccatg cgcgtgcgcg gctggtactt gccgggctgc
    44641 agcgcgatcg tgggcaggga ttgcagctcg cccttgtcga cttcctcttc ctggttcgcg
    44701 gccagcagcg cgtcgagtcc gcggccgagg cccttgagtc tgggtttgtt catgtcggtt
    44761 ccggaattca gaaggtcttc gcgcgctcga tcatctcgtg cgcgaaggcc atgtaggcct
    44821 gcgcaccctt ggccgccttg tcgaacacca cgcccggcat gccgtggctc ggcgcctcgg
    44881 ccaggcgcac gttgcgcggc acgatggcgc ggaagacctt gtcgccgaag tggccctcga
    44941 gctggttcga cacctgctgc tgcagcgtta cgcgcgggtc gaacatcacc cgcagcaggc
    45001 cgatgatctt gaggtcgcgg ttgaggttgg cgtgcacctt cttgatcgtg ttgaccaggt
    45061 cggacaaccc ctccaacgcg tagtactcgc actgcatcgg gatgatcacc ccggtggcgc
    45121 agcacaggcc gttgagggtc agcatcgaca gcgagggcgg gcagtcgatg aggacgaagt
    45181 cgtagtcgtc gccgaaggcg gcgagcgcgt tgcgcaggcg cttctcgcgc tggtcgaggt
    45241 tgaccagctc gacctcggcg ccggcgaggt cgcgattggc cggcagcacg tcgtagccgc
    45301 cggtgggcga gaccacccgc accccggcga ggtcgaccat gccgacgagc aggtgataca
    45361 ccgagctctt gagctcgcgc ttgtcgaccc cgctgcccat ggtggcgttg ccctgcggat
    45421 cgaggtcgat cagcagcacg cgctgcccgg cctggtgcag ggcggcggcg agattgacgc
    45481 aggtggtggt cttgcccacc ccgcccttct ggtttgcgac gcagaatatc ttggccatgt
    45541 cggttcaggc tgttccgttt gcggggctcg cacgcgcggt gcaaaccccg gagtgtactt
    45601 caatgcggcg atgcaacatg cacgacgcgc ctcagggctg cagtgtcacg cccgccggat
    45661 gaccagcaga tgacgctcgg cgcccagccc aggcaccgtc agcgcatggg tctcggtcac
    45721 cgcccagccg gcgggcagcg cggcgatctc gtcgagcgga ttcacgccct tcatcgcata
    45781 cagcgcgccg ccctcggcga cgaggtggcc cgacaagccg gtgaagtcgg ccaggctgga
    45841 gaaggcgcgc gagatcacgc cctccggcgc gccaccgggc agcatctcgg gctgcacctg
    45901 ttcgacgcgc ttgttcagta cggtgaaatt gcccaggccg agctcgatct tcgcttgctg
    45961 ctggaagctc gccttcttgc cgacggtctc gatcgaagac gccaccagcc ccggccgcac
    46021 gatcgccagc accacgcccg gcaggccgcc gccggagccg atgtcggcga gccggttcac
    46081 cgccgccagt tgcggcagca ccgcgagcga atcgagcagg tgatgggtga tcagctcctg
    46141 cgggctgcgg atcgcggtga ggttgtagac cttgttccac ttcagcagca gctcgccgaa
    46201 cgcgagcagg cggtcgatgg tctcctgcgg cagcgcgagg ccgagcgcgg cgacaccgtc
    46261 ggcgagctgc gcggcgtagg gttgaaggcg cccgctcatg ccgccggcct ttgcgcgacg
    46321 ttctcgccac cgccctcgcc agaggccgct gccgcacctg cgcgcgccgc cagctcgcgg
    46381 cgcttgagcc acaccagcag cagcgagatc gccgccgggg tcacgccctg gatgcgaccg
    46441 gcctggccga tggtctcggg cttgtgctgg ttgagcttct gctgcacttc cttcgacagc
    46501 ccgcgcacct gcgcatagtc gagctccacc ggcaggcgcg tggcctcggc ctgggcctgc
    46561 ttcgccacct cttcctgctg gcggtcgatg tagccctggt acttggcggc gatctcgatc
    46621 tgctcgatca cctgcgggtc ggtctcgcgc tcttccggcg cgccgggcag gctcatcagc
    46681 gatgcgtagc tcgtctccgg ccggcgcagc agctcgaagt agcgctgttc gcgctcgagc
    46741 gccttgccga gcacgcgctg ctggtcgtcg gcgggaatcg cctccggccg ggcccacgcc
    46801 gccttcaact gcgccgtacc gcgctcgatc gcctcgcgct tggcgcagaa ggcggcccag
    46861 cgttcgtcat ccaccagccc gagctcgcgc cccttctcgg tgaggcgcag gtcggcgttg
    46921 tcctcgcgca agctcaaacg gtactcggcg cgcgaggtga acatgcggta gggctcggac
    46981 acgccgcgcg tgatcaggtc gtccaccagc acaccgaggt aggcctcgtc gcggcgcgga
    47041 caccacggct cgcggccctg cacctgcagc gcggcgttgg cgccggcgag caggccctgc
    47101 gcggcggctt cctcgtagcc ggtggtgccg ttgatctggc cggcgaagaa gagcccggcg
    47161 atcgacttgg tctccagact ggacttgagg ttgcgcgggt cgaagtagtc gtactcgatc
    47221 gcgtagcccg gacgcaggat gtgggcgttc tccaggccgc ggatgctgcg cacgatctgc
    47281 agctgcacgt cgaagggcag cgaggtcgag atcccgttgg ggtagatctc gtgcgtctcc
    47341 aggccctcgg gctcgaggaa gatgttgtgc tggtccttgt ccgcgaagcg atggatcttg
    47401 tcctcgatcg acgggcagta gcgcgggccg acaccctcga tcacgccgga atacatcggc
    47461 gagcggtcga ggttggcgcg gatcacgtcg tgcgtgcgct cgttggtctg cgtcatccag
    47521 cacggcagct ggcgcggatg ctggccggca tggccgagga agctgaacac cggcaccggg
    47581 tcgtcgcccg gctgcaccgt catcaccgag aagtcgatcg tgcgcgcatc cagccgcggc
    47641 ggcgtgccgg tcttcaagcg gccctgcggc aaggccagtt ccttgagccg ctggccgagc
    47701 gagatcgccg gcggatcacc cgcgcgcccc gccgagtagt tctgcatccc cacatgcacg
    47761 aggccgttga ggaaggtccc cgcggtcagc accaccgccg gtgcctcgaa gcgcaggccg
    47821 atctgggtga ccacgccggt gacgcggtcg ccgaacacgg tgaggtcgtc caccgcctgc
    47881 tggaacagcc acagcttggg ctggttctcc agccggcgac ggatcgccgc cttgtacagc
    47941 acgcggtcgg cctgggcgcg ggtggcgcgc accgccggcc ccttggaggc gttgaggatg
    48001 cggaactgga tgccgccctc gtcggtggcc gccgccatcg cgccgccgag cgcatcgacc
    48061 tccttgacca ggtggccctt gccgatgccg ccgatcgagg ggttgcagct catcgcgccg
    48121 agcgtctcga tattgtgggt gagcagcagc gtggccgcgc ccatgcgcgc cgcagcgagc
    48181 gcggcctcgg tcccggcgtg accgccgccg accacgatga catcgaaacg ggtggggtag
    48241 agcatggcgc gctccgtgct gcaatgcgtg aacaaggggc aggattctac gcgcttcacg
    48301 cgtgagcggc caggttccgc gttagtgttt cacggaattt tgcaatccaa acatcagctt
    48361 attaagtgga tcgacgcacg gattcatgac ctcccgcacg ccccccgaag cgccaccacg
    48421 gcagcacccg gctcatcgac agcacctcgc cgctctgcat cggcgcatag ccgggcaggg
    48481 cggcgaggcg ctcctgccac gcggcggtgc gcagcagcgc gagcagggcg cgggtggcgt
    48541 cgtgctccag cgtggacttg aggcaggcga ggaagtaggc ctcctcgacc agcggcacga
    48601 aatccagccc gcggctgcgc gcgctcgcct cgatgccgaa gccggcgtcg gcctggccgc
    48661 tcgccaccgc ctgcgcgacc gcggcgtgcg agggttcgtc ggtggcgtag ccggcgatcg
    48721 ccgccggcgc gatgccgagc tcaccgagga gctcgtcgaa cagcacccgc gtgccggtgc
    48781 cgcgcgcacg attgacgaag cgcacgccag ggcgcgccag gtcggcgagg ccatgcaggc
    48841 cgcacggatt gccgcgcgcc acgatcaggc cctggctgcg gcgggcgaag ccgatcagct
    48901 tgtgcaggcc ggggcgcagc agcggcttgt aggtgcgctg cgacagcgac gcgggtgccg
    48961 ccggcaggcg caggtggaag ccggccatgg tgcagcggcc ctcgttcaac gcacggatcg
    49021 cgtccacgct gccggtgaag cggatgtcca ggtgcaggcc gcacgtgcgc gcctcctcgc
    49081 cgagcgcggc gagcgcctcg tcgtggctgg cgtggaagga cagcacatgc accgagtcgt
    49141 cgaaggcgat cgcgaacgca cgctcgaggt ccgcgcgcag cgcctcgatc tgcggcagca
    49201 ggcgggcctg cacctggcgc tcggcgagca gcagcttggc gccgaactcg gacaggcggg
    49261 cagcctgccc cttctcccac aggatcagcg gctggcccag ctcgagctcc cagcgcttga
    49321 gctcgcccca gacatggcgg taggagagct ccagcacgcg cgcggcggcg gagatcgacc
    49381 cctgctcgcg cacggcctgc aggagatcga ggagcgggtt gtggagcggc gcagaccccg
    49441 tgtcggcgcc gagtacatag ttcagcctga tcctgcgcat cgcccgcccg ctctccgtgt
    49501 ttgccgccat cgtgccggcc tcgtgcgagg ttagcgcaag cgcatcgtcc gcggcgagcc
    49561 cggtgcccct tgcggcgcgg caaggacttg aggatgcggg atttcccgtg gcattgcggg
    49621 cggatttgca aggcccggtc accctgctac acttggcagt gtaatagttt gatatccaat
    49681 attcagcgac ctcacatttc cgtaccgagg aaccgacatg gacagcgtca atctcgagac
    49741 cttgcgccag gccgtcgcct ggcaggcggc cgggctgccg gtcacgctcg ccaccgtggt
    49801 gcgcacctgg ggctcctcgc cgcggccgga aggggcgctg ctggcgatct gcggcgacgg
    49861 ccggctcgcc ggctcggtct cgggcggctg catcgaggac gacctcggcg atcgcctgcg
    49921 cacgcacagg ctccaggccc cggaggtcgt cacctacggc atcaccgccg accagacccg
    49981 gcgcttccag ctgccctgcg gcggatcgct cagcctggtg ctcgagccgc tgcacgccgg
    50041 cagccggctc gccgaggccc tcgcccgcat cgagcgcgga gaactgctcg cccgccgggt
    50101 gaacctcgcc actggcaccg tggagctgct cgacaccgcc cccgacagcg cggtggtgtt
    50161 cgacgacacc cagctcaccg ccgcattcgg gccgcgctgg cgcatgctga tcgtcggcgc
    50221 cggccagctc tccgcctatc tcgcccagtt cgcgctcgcg ctcgactacc gcgtcacgct
    50281 cagcgagccg cgcgaggaat accgcgcgag ctggacgctg cccggcgtcg acatcaccac
    50341 cgagatgccg gacgacgcgg tcgccgcgat gcggcccgac cgccgcagcg tgatcgtcgc
    50401 cgcagcccac gaccccaagc tcgatgacct cgccctcatc gacgcgctgc acaccgacgc
    50461 cttctacatc ggcgcggtgg gctcgcgtgc caccagcgcc gcccgccgcg agcgcctgcg
    50521 cctgttcgac ctcgacgacg cccggatcgc ccgcctgcac gcgccggcag gcctgccgct
    50581 gggcagccgc acgccacccg agatcgcgct cgcgatcgtc gccgacctca ccgcgcgccg
    50641 caacggcgcg agcgtgacgg ccaccgtcga gcgccccgcg accgagtccg ccgcatgccc
    50701 gctcgcacgc gcggcctgat cgtcggcatc ctgctcgccg cgggcgcggg aagccgcttc
    50761 ggcggcggca agctcctggc ccgcctggcc gacgaccgcg gcgtggccga gaccgcctgc
    50821 gcccgcctgc tgccggcggt cgatcgcgtg gtggcggtcg tacccgcgca gcccggcgcg
    50881 ctcgaggacg cgctgcgtgc ggcgggcgcc gaggtggtgc gctgcgacac ggaggcgcct
    50941 ggcatgggcg tcagcatcgc ctgcggcgta tccgccagcg ccgacgccgc aggctggctg
    51001 gtcgcgctcg gcgacatgcc cctggtgccc acctcccagc accgcgtggt cgccgacgcg
    51061 ctgcgcgccg gcgccgacat cgccgccccg gtctgccagg gccgtcgcgg ccatccggtg
    51121 ggcttcgccg cacgcttcgg cgacgagctg cgcgccctcg acggcgacga gggcgcgcgc
    51181 gccgtgctcg cccgccaccg cgaagcgctg ctcgaactcg ccgtcgacga cgacgcaggc
    51241 tggcaggaca tcgacacgcc atccgacctg gccgccgtga atcgccgcct cggcagaccc
    51301 tgaacgccct ccccggcacg gcaagcacgc atcgccggga gcgcccgaca cgcccttcgc
    51361 ctatgcaggg gtgcgcatag gatcagatca ttttagatct tattcgtgga tatctaataa
    51421 tctttaagat actgttttaa atcggcttat agattttgtg atacgttctg tttgattttt
    51481 tgatattttt ttgtatcatc gaatcaagcc gcggcacgat cctcttgcgg ctccgtcccg
    51541 acaggaggtc cccatgctcg accaccccta cccagcaagc ggcgcgcacc gcagctacgg
    51601 cgtcgaacgc cggggcaccg actccgcgat cctcggcgag gatgcggtcg ccgaagaggc
    51661 gccggtcgcc ctcgtctata acggcttctc ccacgcggtc atgctcgcca ccccgcagga
    51721 cctcgaagac ttcgcgctcg gcttcacgct cagcgagggc atcgccgcaa gcgcacgcga
    51781 actccacgac atcgacgtcg tcgagcacgc cctcggctgc gaggtgcgca tggcgctcgc
    51841 cggcgaacgc ttcgccgcca tgcgcgaacg ccgccgcgcg ctcgccggac gcaccggctg
    51901 cggcctgtgc ggcatcgaga gcctcgccca gctgcagcgc gcgctgccgc ccgcccgcct
    51961 cgccgagacc gcaatccagc ccggcgcgct cgagcgcgcc caggccgagc tcgccgcgct
    52021 gcagccactg ttccagctca ccggcgcggt gcatgcggcg gcgtggtgcc ggcgcgacgg
    52081 cagcgtcgcg ctggtgcgcg aggacgtcgg ccgccacaac gcgctcgaca agctcatcgg
    52141 cgcgatcgcc acgcgcggct gcggcttcga cgacggcttc gtgctgatga ccagccgcgc
    52201 cagctacgag atcgtgcaga aggccgccac cgtgggcatc gccgcgatcg ccgcgctgtc
    52261 ggcacccacc ggcatggcgg tgcgcctggc cgaggccgcc ggcgtcaccc tggtcggctt
    52321 cgcgcgcggc caccgccaca gcgtctacac ccacccgcaa cgcatgcact gagcgaggag
    52381 tccgcgatga ccgccgccac cgcccgcaac gaacgcaagg tcccgagcta ctgctacaac
    52441 tgcgtcgccg ggcccgactt catgaacgtc aaggtgatcg acggtgtggc caccgagatc
    52501 gagcccaact tcgccgccgc cgaggtccat cccgcgcgcg gccgcgtgtg cgtgaaggcg
    52561 cacggcctgg tgcagaagac ctacaaccca caccgcatcc tgcagccgat gaagcgcacc
    52621 aacccgaaga aggggcgcaa cgaggacccc ggcttcgtac cgatctcctg ggacgaggcc
    52681 ctcgacacca tcgccgcccg cctcgccgcg gtacgcgaga agggcctggt cgacgacgcc
    52741 ggcctgccgc gcgtggcggc gagcttcggc cacggcggca cgccagcgat gtacatgggc
    52801 accctgcccg ccttcctcgc ggcgtggggg ccgatcgact tcagcttcgg ctccggccag
    52861 ggtgtcaagt gcgtgcactc cgagcacctc tacggcgagt tctggcaccg cgccttcacg
    52921 gtcgccgccg acacgcccaa ctgccgctac gtgatctcga tcggcagcaa cgtcgacgcc
    52981 tccggcggcc cgtgcgcggt cacccgccac gccgacgcgc gcgtgcgcgg ctacaagcgc
    53041 gtgcaggtcg agccccacct gtcggtcacc ggcgcctgtg cctccgagtg ggtgccgatc
    53101 cgccccaaga ccgaccctgc cttcatgttc gcgctcatcc acgtgctggt gtgcgaacac
    53161 ggcgtcggcc agctcgacct gcccttcctg cgcgaccgta cctcctcgcc ctacctggtc
    53221 ggccccgacg gcctctacct gcgcgacccc gacagcgcca ggccgctggt gtgggatccc
    53281 gtcgccggcc gcgccgtgcc cttcgacacc ccgggcgtcc agcccgcgct cgagggccgc
    53341 ttccgcgtcg ccgcggcggt cacggtggat gcggacgacg cccgccagcc gctcgccgac
    53401 gtggagggcg tgcccgccca cacgatgctg gtcgagcaca tgcgcaaata cacgccggag
    53461 tgggcggagg gcatctgcga cgtgcctgcg gccaccatcc gccgcatcgc cggcgaatac
    53521 ctcgagaacg cacagatcgg cgccaccatc gaggtcgatg gcgccaccct gccgctgcgc
    53581 ccggtcgcgg tcaccctcgg caagtcggtg aacaacggct ggggcgcctt cgagtgctgc
    53641 tgggcacgca ccgtgctcgc caccctggta ggcgcgctcg aggtcccggg cggcaccctc
    53701 ggcaccacgg tgcggctcaa ccgcccgcac gacgaccgcc acctcagcgt cgccgccggc
    53761 gaggacggct tcatggcgca aaaattcaac cccaccgaca aggcgcactg ggtcgcccag
    53821 cccaccggcc gcaacgccca ccgcaccctg gtgccgatcg tcggcaattc ggcatggagc
    53881 caggcgctcg gccccaccca gctggcgtgg atgttccagc gcgaggtgcc gcgcgacttc
    53941 aacatgccca agccgaccct gcccgacatc tggttcatct accgctccaa cccggcgatc
    54001 tcgttctggg acacgcccag cctggtggag acgatcgcca ccttcccctt caccgtgtcc
    54061 ttcgcctaca cggtggatga gaccaacttc ttcgccgacc tgctgctgcc cgaggccacc
    54121 gacctcgagt ccctgcagat gatcaaggtc ggcggcacca agttcgtcga gcagttctgg
    54181 accgcgcgcg gcgtcgtgct gcgccagccc gcggtcgagc cgcagggcga ggcgcgcgac
    54241 ttcacctgga tcagcaccga gctggcacgt cgcacgggcc tgctcgagcc ctacaacaag
    54301 gcgatcaacc gcggcgccgg cggggtctcg ccgctcaccg gcgagggcta cgacttcagc
    54361 ctcgacccca cgcgtacgca cgatgtcgac acgatctggg acgcgatctg ccgcgccgcg
    54421 agcaccgacc tctcgcaggg ccgcgagacc cacgacctcg cctggttcaa ggagcacggc
    54481 ttctacaccg tgccgatgcc gcagcgctcg tggtacctga cccccaccct ggccgagaag
    54541 ggcctgcgct acgagctgcc ctaccaggag cgcctgctgc gcatcggccg cgagctcggc
    54601 aaccgcctgc acgagcacgg catgcactgg tgggacacgc agctctccga atacaccgcc
    54661 ctgcccgaat ggcacgacgt ccccgggcgc tgggagcagg ccctggtcga cagcggcgcg
    54721 aagcccgagg actacccgct gtggctgctc gccaccaaga gcatgcagta ccacaccggc
    54781 ggcaacgtca gcatcgcgct gatgcgcgag gtggcgcaga acgtgcgcgg ccacgccggg
    54841 gtgatcatga acgccaatac cgccaagggc ctcggcatcg ccgacggcga ccgcgtcgag
    54901 atccgctcgc acatcggcgc cacctatggc aaggccgtcc tcgcccacgg catccgcccc
    54961 gacaccctgg tgatcccggg ccagttcgac cactgggcca cgccggtcgc caaggacttc
    55021 ggcatgccca gcctcaacac cgtggcgccg atgtcgctcg agctcaccga cgccaccggc
    55081 tcgggcgccg acatcgtgcg cgtggcgatc cgccgtctcg aagggagcac cgtgcaatga
    55141 cccgctatgt gatgagcatc gatctgcgcc gctgcgtggg ctgccagacc tgcaccgcgg
    55201 cgtgcaagaa cgccaacgcc accccgcccg gcgtgcagtg gcgccgcgtg ctcgacctcg
    55261 agaccggcga gttccccgac gtgcgccgca gcttcctgcc gacggcctgc atgcactgcg
    55321 ccgagccgcc gtgcgcggag gtctgcccca ccgaagcgac gcagaagcgc cgcgacggcc
    55381 tggtcaccat cgactacgac gtctgcatcg gctgcgccaa ctgcgtgatg gcctgcccct
    55441 acgaggcgcg ctcgatcgtg cacgagccgc gcttcgccta cggcgaccag ccgatcgcct
    55501 ccgaggcgat ccgcttcgac ccctcgcgca tctcggtggc gaccaagtgc agcttctgca
    55561 aggagcgcat cgacgccgcc gcggcgagcg ggcgcatccc cgggcgcgac cccgaggtca
    55621 ccccggcctg cgtcaactcc tgcatctcgg gggcgatggt cttcggcgac atcgacgacc
    55681 ccgacagcgc ggtcagccgc ctgctcgcaa aaacccagca cttccacatg cacgaggagc
    55741 tcggcaccgg gccgagcgtc tattacatct gggatcacgc ctgatgaaac cgaaccgtcc
    55801 ccctctcccc ggccagcccg cgccccgcct gcagcagcac tgggactggc gcgccgccgg
    55861 caacttcatc tgcggcggca gcggcggcgg gctcgtcctg ttcgccgggc tcgccggcct
    55921 aaccggcgcc gaagtgcgtc cgcagctcgc cgccggcctc gtcctcgtgg cgctcgggct
    55981 gctctgcgtc tggttcgaga tcggccggcc gtggcgcgca ctcaacgtct tccgccacat
    56041 ccgcagctcg tggatgacgc gcgaggcctc ggtcgcgctg gcgctgttcg gcgccggcgc
    56101 gctcgccctg ctcaccgcgc accccaccgc gcaggcgctc gccggcctgt gcggcctcgc
    56161 cttcgtgtat gcgcaggcgc gcatcctcgc cgccgacaag ggcatccccg cctggcgcca
    56221 cgcgcgctgc gcgccgctgg tgctgggctc cgggctggcc gagggcgcgg gcctgatcgc
    56281 cgtcaccctg gcgggcgggc ttcagctcgc cgccgcggcc gtcctggtac tggccctgtc
    56341 cgcccgcctg ctcttgtgga gacgctacct tgacggcctg cgcgccgatc acgccccggc
    56401 ggccagcgtg caggccttcg acgccatcgc gccgcgcctg gtgcgcttcg gccacctgct
    56461 ggcgggcggg ctcgcactgc tcgccgcggc cggcgccctc ggcggcctgc ccggcgcagg
    56521 catcgcgctc gccgccgcgg gtctgctcgc agccggcgcc ggctggtggt tcaagtacac
    56581 gctgatccgc cgcgccgcct tcacccaggg catcgcgctc aagcatcacc ccgtgcgcgg
    56641 cggcaagccc gcgagcctcg ccagcacgcc ccgcctcggc aacgcctgag cggccgtggt
    56701 ggcgggcgcc cggcggctcc cgctcagccc tccaccgcga cctcgtccgt cgccgctggc
    56761 ggcgactcca ggccgccgaa gcggcggaag aactgcgccg acggtggcgg cagcgggccc
    56821 tcgggcgtcg cacagctcgc ctgcagatgc tggcaggccg cacgccaggt caggcgatag
    56881 agctgcgcac atagctcgcg cgccgcatcc ccgcgccagc ggttgggcat cacctgcacc
    56941 ggcagctgcg ggtcgtgcag cagcacgcgg cggaactcgt gcatcaacag ggtctgcacc
    57001 aggaaggcct gctccggctc gacctcgccc gcgccgaagg cgcgcagcag cgggcggaag
    57061 tgttcgatga aggcgtcgta ggtggcggcg atcgcctgca ggtcccagca ctcgcgcacc
    57121 agctcgtcgg tggccgcccc ggtcaccccg tccaggccgc gcgcggtcag cggcaccacg
    57181 cgatcgcgca ggccgcagcc gtcgaggatg ttgcgcagcg tcgaggcgtc gtcggtgggg
    57241 cgcaacagca cgcccgcatt cagcgccccg tagcccgccc acgacagctc ccggcgcagg
    57301 ttgtccgcca cccgtgcgtc gagcgcggag ggcagcatca ccacctgcca ggtgccgctc
    57361 cagccctcgc cctccggctc gaagatgcgc cgccacgccg gcgcgaagcg gcgcatgccc
    57421 gccgcggcga ggcggtagta gctgcgccgg ccgacctgcc ccgactccag ccagtcgtcc
    57481 tgcaccagcc gatagacgct ggtgcgcacc acgcgctcgt tgagcccgaa gggcgccatc
    57541 agccggatca ggtcggccag ccacaccacg ccgccgtgca ccgcgatcag gtcgccatac
    57601 accgagatga tcagcgagtt ggcgctgatg cgccgtccgg cgaggtgggc ctcgacccag
    57661 cgttcgatca cgcggctctt catgctttct ggtccatgtc cgtgtcgcac cgcggcgtcc
    57721 cggccgccgc cgcccttcat cctatgcagg gccgttcata ttgatccatc ccacccgcct
    57781 gcctagattg cccgaggcgc gtccgtcgcc gcagccgccg cgacggcaac acaagcaccc
    57841 ggcccgagcc cggccccaat cgaggagact ccgcatgacc cgcaacaccc gcaacacccg
    57901 catcgcgcgc atccgccgca ccgtcgccgg catcgccacc gtggcgatcg gcctcttcgc
    57961 cgcccccgca accgcccagc aggctgcctc gatcgtcgtc gcctcgacga cctccaccga
    58021 gcagtccggg ctcttcggcc acattctgcc gcagttcaaa caggcgaccg gtatcgacgt
    58081 gaaggtggtc gcgctcggca ccggccaggc cctcgacgtc ggccgccgcg gcgacgccga
    58141 cgtggtgttc gtgcatgacg ccgccgccga acagaagttc gtcgacgaag gtcacggcat
    58201 cgagcaccgc aaggtcatgt acaacgactt cgtgctaatc ggacccaagg acgaccccgc
    58261 cgcgaccaag ggcaaggaca tcaccggcgc gctgcagaag ctcgccgccg ccaacgccag
    58321 cttcgtctcg cgcggcgaca agagcggcac ccacgccgcc gagctgcgct actggaaggc
    58381 cgccgccgtc gacaacaagg gcgcgggcta caaggagtgc ggctgcggca tgggcccggc
    58441 gctcaacatg gcggcgtcga gcggcgccta cgtgctcgcc gaccgcggca cctggctcag
    58501 cttcaagaac cgcgccgacc tcgcggtgct ggtcgaaggc gacaagcgcc tcttcaacca
    58561 gtacggcgtg atggtggtga accccgagcg ccacccgcac gtgaagcagg ccgaggcgcg
    58621 caagttcgtc gagtgggtgg tgtcgcccgc cggccaggag gccatcgccg catacaagat
    58681 cgagggcgag cagctcttct tcccgaacgc cgggcagtaa ggcgggcggg ggctcccgtc
    58741 cgcagtaacg acacggacca acgatgcgaa gacgcggact ccaggctccg cgcttcctgc
    58801 aggagcgtcg gcaggcgcga gggcgcccta ccgccccctt caccgccccg cccatccacc
    58861 cgccgcattc gcgcctgccg gcgctcccac agccacccca accagggcag cgcgtcagac
    58921 acagcggcgc acacgcgagg ccgcggggcc ggggcggcgg tcgccaactt caggagcgcc
    58981 gaggcggagg gcgtcgcggg ggaatgtagg agcgccggca ggcgcgaatg cgacggcatg
    59041 acaatcgatg cgcttgccga aagccacgca agtaccagcc tgaaccgccg cattcgcgca
    59101 cctcctgcgc cggcgctcct acagccacgt acaatcaggg cagcgcatag agccaggcgc
    59161 gcacagcacc gccccggccc cgcggccgga tcggcgccgc gcaaaccctc aggccacgct
    59221 acgccaccaa acgaagcgag gcacacggga gcatcgcttc ccacaccacg ctgaacccgc
    59281 tccgccccca cccccaagtt cctccgctgc cgcaacgggg ccaagccccg caagccgcct
    59341 caggtcgcga tgccgccggt gtcaaacacc tcggcatgga tgcgcgccga ctcgaccccc
    59401 agcgcgtgca gcgtcgcgat ctgcgcctcc aggaagccga ccgggccgca caggtagtaa
    59461 tcggccccct cggccagcac ctcgcccgcg agcgcgcgca ggtcgacccg cccggactgc
    59521 accggcgccg cggccgcacc ctcgtcgtgg aacagatgca gcttcacctg cggatgacgc
    59581 tcggcgagcc tggccaggtg cgctccgaag gcgaacaccg cggcattgcg gcaggcatgc
    59641 acgaactgca ccggccgcga cggcgccgtc gccacgaggc ggtcgagcat cgccaccatc
    59701 ggcgtgatgc ctacgccgcc gctgatcagc accaccggcc cgtcgtgcgt ctcgtcgagg
    59761 aagaactcgc cgaagggcgg tgccagctcc agcatgtcac ccaccttgta gaagtcgtgc
    59821 aggcggttcg acacgcggcc agccggcgtg gtcgtgctcg ccggctcgcg cttcaccgag
    59881 atgcggaagt gcatggcccc cggcgcgatc gacagcgtgt attggcgcag ctgcgtcacg
    59941 ccgagctcgg gcacgaacac gcgcgcggtc gtgtactggc cggcgcggta ggccggcagc
    60001 ggcccgccat cgcagggcac gaggtggaag gaggtgatct cctcgctctc gcgcaccttg
    60061 tcgatgatgc ggaagctgcg ccagccgctc cagccgccgt cgctgttgca ggcctcgttg
    60121 tagagcttgc tctcggcctc gatgaagacg tcggcgagcg cgccgtaggc gacgccccag
    60181 gcatggatca gctcgtcgct cgcggcgtcg cccagcacct cgcggatcga ggccagcagg
    60241 tgcttgccga cgatcgggta atgctcggcg cggataccca cgctggcgtg cttgttggcg
    60301 atcagcgtga tcaccggcgc cagcaccgag ggatcgtcga tgttctcggc gtaggccagc
    60361 accgccatcg ccagtgccac cggctgcttt ccggtctcgt tgtgcgactg gttgaagatg
    60421 ttcttcagtt ccgggttgtg gcggaacatg cgctggtaga aatacgtcgt cagggcgacc
    60481 ccgtgctcct tgagcaccgg gatggtggcc ttgaccagtt cgcgaacgcg ggcgtccatg
    60541 tcgtctcctt gggggtcggt ccgcgcgcgg cggacttcat tcggatgggc tcggcgcggc
    60601 gcaaggtgcc acgcaggcac cggatcttgg acgccgacac ccccggccgc tatccactca
    60661 caacgtgaca tatatccaga ttgtgcacac tcgcgctcag gcgccgggca gcggcagcgc
    60721 cgtcttgtcg atcacccgcc gcagcacgaa gctcgaatgc acgccggtca cgccggggat
    60781 gcgggtgatg cgctcgagca gcagcgcctg gtagccgtcc atgtcggtga ccacgacctt
    60841 gagctggtag tcggcgtcct gtccggtgat cagcaggcac tccagcacct gcgggatctg
    60901 ctccacctcg gcctcgaagt gcgagaagcg ctcgggggtg tggcggtcca tcgagatgtg
    60961 gatcagcgcc atcagcgaca ggcccagctt cctggcgtcg agcagggcgc ggtagccgcg
    61021 gatcaggccg gactcctcca gcgcgcgcag ccggcgcagg caggccgagg gcgacagcgc
    61081 gatgcggtcg gcgaggtcct ggttgctgat gcggccatcc tgctggagca gctccaggat
    61141 ctggcggtcg tagcggtcga gctgcatgat cgggcgcctc atctgaacag gaaagcagat
    61201 tattccaatc aataagaatc tattgaactt ttctgcacaa aaatacctgc tcgcactgca
    61261 acaacgcaat cgtctgccgc acccggccgc gtaaactttc gtccatcgaa tcacgccatg
    61321 cccacgagga ccgcgccatg atgttgccca accccgccgc caagtaccgc cccttcgccc
    61381 caatcgcgct cgccgaccgc cagtggccga acaagctcat cgaccgcgcc ccgatctgga
    61441 tgagcaccga cctgcgcgac ggcaaccagg cgctgttcga gccgatgaac gtcgagcgca
    61501 agatgcgcat gttccgcacc gtgtgcgaga tcggcttcaa ggagatcgag gtcggcttcc
    61561 cgtcggcctc gcagaccgac ttcgacttcg tccgcacgtt gatcgagggc ggccacatcc
    61621 cgcaggacgt caccatccag gtgctcaccc aggcgcgcga ggacctcatc cgccgcacca
    61681 tggaatcggt ccgcggcgcg ccgcgggcga tcatccacgt ctataacgcc acctcaccca
    61741 ccttccgcga ggtcgtgttc ggcttggaga agccgcaggt ggtggcactt gcggtgtcgg
    61801 cggtgcgcct gatcaagcag atcggcgcgg aaatgaagaa ggagtgcggc accgagatcg
    61861 ccctcgagta cagcccggag accttctccg ccaccgagct cgaattcgcc agggaggtct
    61921 gcgacgccgt caccgccgag tggggcgcga cgccggacga caaggtgatc ctcaacctcc
    61981 cggccacggt ggaggtgtcg acccccaacg tctatgccga ccaggtcgag tggatgcacc
    62041 gccatctcgc gcgccgcgac agcgtggtgc tctcgctcca cccccacaac gaccgcggca
    62101 gcggcgttgc cgccgccgag ctcggcctga tggccggcgc cgaccgcgtc gagggctgcc
    62161 tgttcggcaa cggcgagcgc accggcaacg tcgacatcgt caccctcgcc ttgaacatgt
    62221 acacccaggg cgtgtcgccc gggctcgact tctccgacat caacgcggtc gcgcgcaccg
    62281 tcgagtactg caaccagctg cccatccacc cacgccaccc ctatgtgggg gatctcgtgt
    62341 tcacggcctt ctccggctcc caccaggacg ccatcaagaa gggattcgcc gcccagaagg
    62401 cactcagtgg cgaaactcgg ccgtggaacg tgccctacct cccgatcgac cccgccgacg
    62461 tcggccgcag ctacgactcc gtgatccggg tcaacagcca gtccggcaag ggcggcgtcg
    62521 cctacctgct cgagaccgag tacggcgtcg tgatgccgcg ccgcctgcag gtggagttct
    62581 cgcgcgaggt gcagcaggtc accgacgcca gcggcggcga gatgtcggca gcggcgatct
    62641 gggcgctctt ccgcagcacc tacctcgaca cggtggatcc ggtgcgctac gtcgagcacc
    62701 acctgttcga gcacggtgcg gcgcagggca tccgcctcgt cgtcgagttc ggcggcaccc
    62761 gccacctgct cgtcggcgag ggtaacggtc ccatcgacgc cgcggtgcac gccctgcgcg
    62821 gcgccggcat cgacgtccag gtgcgcagct tcgaggagcg ctcggtggcg ccgagcgagg
    62881 atggcggcaa cgccagcgcc tgcgccttcg tggagctgag cgaggtgggc gggcagggcg
    62941 gcgagcgcta cggcgtgggc atggacgcca acatcgtcac cgcctcgatc cgcgccctcc
    63001 tcagcggggt caaccgcctg cagccggcgt tcgcccgcgc acctgcggcg cgtgcagcct
    63061 gagcagcggt ggcggcaccc gccgccgccc ctaggacggc cggttgccgc aagccgcggc
    63121 cgccgcccgc gtcgtgctgc agctcgcgca gtagtaaccg tagcgcgagc tgccacgcac
    63181 cacctggcgg cgcccgctca ccgactggcg cttgccgcag cgccggcaca tgaaggtggg
    63241 gatggtcacg ccggccagct tggcctggcg ctcggtggcg tcgcgataca gttcgatcgc
    63301 gcatttttgg ccgtagccgg atctgaagct catcgcacaa cctcctgccc ggaaatcttc
    63361 acgactgcag caccccgact ccgcgcccgt gcagcgcatc gaggcgaacg agcagatcct
    63421 gcggcacgat ctcgacgacc gctgcggcgc ccgcatggat cgcaccctcg ttgccatcca
    63481 gggtcagcag ctcaccctcg cgcaggatat ggccgccgat ctcgagcgtg cgctccgcct
    63541 cgtcgagacg caaggcctcg cagcccacca ggcagacctt gccgagctgg cgtgcgacca
    63601 ccgcggcgtg cgaggtgcgc gcgccgcgtc gggtgagcag gccctcggcg agctcgagcg
    63661 cggcgaggtc gcgcgtctcg gcgtcctggc gcaccaggat cagcttcgcc cccgcggcac
    63721 ggcgggcgcg ggcgcgcgcc tcgtcgaaga cgatctcgcc gcaggccacc ccgctcgccg
    63781 cgctcgcagc gtgcccgagc ggcacgagcg cgaccccgtc ggcgttggcg atgcggtgct
    63841 cggcgagcac gcgcgcatcc agcgtcgcgg tgcgcgcgcg cgcggtttcg gcgtcgatca
    63901 cgccctcgtc gaacaggtcg agcgcgatcc gcgccgcggc ccggggcgtg cgcttgccgg
    63961 tgcgcgtctg cagcaggtgg agcacgccct gctgcacggt gaactcgaaa tcctgcatgt
    64021 cgccgaaggc gcgctccagg cgggcggtgg cgtcgagcag ggcctgccac accgcaggcg
    64081 cgaccgcggc gagctcgtcg tggccgtacg cgctgcgccg gccgctgacc acgtcctcgc
    64141 cctgcgcgtt gaagaggaag tccacccagg gccgcggctc gccgctgctg gggtcgcggg
    64201 tgaagcccac gcccgcgccc gacagcccgc cggcgttgcc gaacaccatg cgctgcacgg
    64261 tcaccgcggt gcccatgtcc tcggccaggc cgtgcatcgc gcggtaggta cgggccttgt
    64321 ccgcgtgcca ggacgcgaac accgcggcga tggcctggcg cagctgctca tgcgcatcct
    64381 gcgggaaggc ctcgccagcc tcgcgccggt aggtgtcgag gtggcgggcg gcgagcgcgc
    64441 gcagggcggc gaagtcgagc gcgcgctcgt cgcacgcgtc gcatccgccg cgcaccgcgt
    64501 cgaggtcggc gtcgaagtgg cgcgcgtcga tcccggcgac cacctcgccg tagccggcga
    64561 tcaggcgccg gaaggcgtcc caggccaggc gcggatggcc gctgacgcgc agcaggccgg
    64621 gcagcgtggt ctcggtgagg ccgatgtcga gcagggtctc catcatcccc ggcatcgaca
    64681 ccggtgcgcc cgagcgcacc gacagcagca gcggatggcg tgtatcgccc aggcgcaacc
    64741 cgctcagtcg ctccagttcg gcgagcgccg gccgccaggc ggcctcgtcg agcgcaccgg
    64801 gttcggcaca ccagccggtg ccgagcacga aggccggtgg caccgggagg ccgagcgcgg
    64861 ccatgcgcgc gaggttccag gccttggagc cgagcgccgc ggcgccgcaa tcctccggca
    64921 gcggtgcagc ggcgtggatc aggcggacga cccggcgcgc gtcggtggat gtggcgacag
    64981 ccctgtccgc gctcatcgcc ccacccctgc gcggctgaag accagccggc gcaggccgta
    65041 gccggtcgcc agcagccagt cggtggccga ctccagcgcc tgcgcgaagt cggtgctcag
    65101 gttcagcgtc gctgcgtcgc tgacgtgctc ggcgagcgcg cggcgcacgt cgcgaagcaa
    65161 cacgtcgcac tggcgctcgg cgttgagcac ccgccacagc gcggcaacga actcttcgtg
    65221 gtcctcggcg ctgctgtcct cgccgaagcc gcgcgcgatc tcgagcgcac gcacgtggtc
    65281 ctgcgccgcc gcgagcacgg cgtcggcgag cagctgcatg gcctggtgca cctcgccgcg
    65341 ccagccctgg tggtggtcgg cggcgatcag cgagagcagg aaggccgcct cctcgagcgc
    65401 atcggcgacg tcgtcggcgg tctccaccag ctcggcgaag gccccccagc gcggccgcgc
    65461 ctcggcgcgc gcgcgcgcat ccatcaccag ctggtcggca cggcgctccc agtccttggc
    65521 gcgctcggag aattcgcgcg ccgccttgcg gtcgcgctcg tggccgtggg cgaggccgtc
    65581 gcgcaggccc tcggcgagcg catggcagta ggccgcgtgc tcggcgagca ggtcgaactc
    65641 gtcgtgccgg cgcaggtagc gcgcgagcag caggcgggtg tcgtcggcca ccagcgcaag
    65701 cggctggcgc tgctgcgtcg ccgcactcgc cagcgccatg ctctcgagca cgaaggcgcg
    65761 cgccttctcg gtgccgagca cgccgtcgag gcggtcgccg atgcggaagt actccggccc
    65821 gagcgcctgc atcgcaccga acaccagctg ctcgccgccc gctgccagcc aggccatgtg
    65881 gccgacgcgc cggcgcgcgg cctcggcgag gatggccgtc gcatcggtct tgccgacgaa
    65941 ctgctcgagc cgcttgcgcg cgcggttcca gtcgatcagg aagacgatgc gcgcgccgat
    66001 gccctccagc acccgctgca gcgcctcctc gtcggcgcag tcgaacccgg cggtgccgac
    66061 gtagtaggtg gcaccgaagt tgagcccggc gctggtgcgc gcctgcggct cgctccagct
    66121 cgccccgacc tcgcacagca gcgactggaa gaaggcgaag cggcggcggt ggaggtcgga
    66181 gtaggtgagc gtgacacgca ggccctcgac ctggatcacc agcacgtggg cgtcgttggt
    66241 gccgatgtcg ttctgcagca gcaggcgggc gccgtcgcgg gtggcggcgg tgtccagccc
    66301 ggggtggtcg agcttgaggg cgcgggtgga atcgagcccg cgcatgaagg cggcgatgcg
    66361 cgggcggtcg agcgcatcga cctgccacac gtgggcgccg tcgatggtct cgctggagag
    66421 ctcggcggcg aggcggttga gcgccttgtg cagatccatc accagcaggt gcaggctgtc
    66481 gtccttgccg cgcttgccac tggtgagcgc ctggagctgc gccgaagaca gcgtgtcggg
    66541 cgcaagctcg gccagccagg cacaccagtg cgcgcagcgc gtgtcgaagt cctcgtcgcc
    66601 ctcgagcggt cgcgccatcg tgcgcaggtc ctcggcaagc agggcgacga ggcggtcgag
    66661 gccggccacg tgcagctcct tgccctcgcg gtaggcggtc gccggcagct gcgccagcca
    66721 gggcgcatcg accccggcgg cggcgaactc gcgtgccagg tcaagcgcag gagcatcgcc
    66781 gcgctgcgcg tggtcgtgcg ccgcctgcag cacgctgaga tagagcttca gtcgatcgtt
    66841 ggcggccagc gccacacgga cccgcgccgg cctgagcagt tccgcctgtc ccaggctggc
    66901 gacggcctcg agcttctcca tggcatcctc ccgttgttcg tgaaggattc tgtgggtgaa
    66961 atgtgacagt catgtcacca tgaagacgca tcttgctgcg ctgcgcaaga cgggcttcac
    67021 gaaaccgcaa tacggctgtc aagcgaccgg cgcacacttt gttcaacgac cagcgcgcaa
    67081 tcgtcggggt agggcagcga ccccatccgc acgggatgcg cacggaggca atcctcatgc
    67141 cagcttcgcg acggggcggc aaacggccgg caacggcccc caccgccaac cagcaacccg
    67201 acccgaatcg cgccccgggc gggtcgaaag gcacgaatgg ccgcaatggc ggcctgcacc
    67261 gccagaacgg cattcccgat ggacgcgcgg tttaccgcca catcgccgcg atcggcgacg
    67321 gcctctccgc ccgcgccgac cccttcggca tcgccgcgcc catcctgcac gcacagatgg
    67381 cctggctcat gcacccgcag gaactcggcg agcgcctcgc cggcctcggc accgacctgt
    67441 ggcagctgca gtggcacacc tggcggcgcg cgctcggcct gcccagcatg gacccggtca
    67501 agccgcacgc cgacgatccc cgcttcgccg acccggtgtg gaccgatacg gccacctggg
    67561 acctggtgaa ggagtggtac ctcgccttca cccaccacgt ccaggacatg ctctacgaga
    67621 cgccggggct gtccggcaag gagcgccggc gcgcggcgtt ctggtggcgg aagtggctca
    67681 acgcggtggc gccgaccaac tacctgtggt ccaacccgat cgcgctgcgc aagttcatcg
    67741 acacccgcgg ccacagcctg tggcagggct ggcagaacat gctcgccgac ctgcaggcgg
    67801 gcaacgtgcg catgaccgac cccgacggct tccacgtcgg cgaggacctc gccaccacgc
    67861 cgggcgcggt gatcttccgc aaccgcctgc tcgaagtcat ccactacgcg cccacccggc
    67921 cgcaggtgca tgccgagccg gtggtgatcg tcacgccgtg gatcaacaag ttctacatcc
    67981 tcgacctcaa cccgaggaag agcatggtgc gcttcctgct cgaccagggc ctggacgtct
    68041 acatcacgag ttggaagaac cccgacgcgt cgatgcgcga gatccgcttc gacgactacc
    68101 tggcggaggg catctcggag atcgtgcggg tggcacgcga ggtcagcgct gccgagcggg
    68161 tgcacgcggt cggctactgc atcggcggca ccgcgctcgc cacctggatg gcctgggcgg
    68221 cgcgccacta cggcgaggac gccgtgccgg tgcgcgactg gacgctgttc accaccctgg
    68281 tggacttcca caagccgggc gacatcgagg tcttcatcga cgaggagagc gtcgcccacc
    68341 tgagcgcgca gatgaatgaa aaaggctacc tggacggcaa ggacatggcc gcatccttcc
    68401 gtctgctgcg ctcgaacagc ctggtctggc actacgtggt gcacggctgg ctgtacggcg
    68461 agtcgcccgc ggccttcgac gtgctgtact ggaacatgga caccacgcgc atgccctgcg
    68521 ccatgcacgc ctggtacctg cgcgagctct acctgaacaa ccgcctcgtc cagcccgacg
    68581 ccctcgtcgt ggccagcgag ctgatcgacc tgcgccgcat ccgccagccc ctctacgcgg
    68641 tggccgcgga agacgaccac atcgcgccct gggcgcagac cttccacacc ctgcaccatg
    68701 tcgccgccga caagcgcttc gtgctgtcga gctccggcca catcctcggc atcatcaacc
    68761 cgccggtgac gccgcccaag cgccactacc gcgtggccac cgcccatcgt gccgatcgcg
    68821 cgccgctctg gcgcgatcgc gccgagctgc gcgaaggcag ctggtgggag gactggatgg
    68881 cctggctgaa gccgcgcgcc ggcgagctgg tgccggcgcg tcccgcggcc gacgagcgcc
    68941 atccggcgct gggcgatgcg ccggggacgt atgtgctgga agcgtgaggg gcgggcgcgg
    69001 ggcggatttc ttgcttggta tcgattcgac aggaggaagc atcatgcaga cacgaggcca
    69061 tctcgccacc cccgctacac cgaatgcaat gcaccctggg ccgcagctcg gccatggggg
    69121 tcttgatcgg cataccaccg cagcctggca agcgcggccg aagaagcacg tcgccgacct
    69181 gctcgacgac gccggcgcgc tcgccgactg gcaccgcaac ctcgagcgcc tgcgccaccc
    69241 cgagcgcggc tgaagccaca gcgcgcaatc cggggaagac cggcgcggtc tggacccacg
    69301 ttgccgaccc gggcgaggag tgctgcgccg cagcgtctcc gagctcgggt ttctacgcta
    69361 tattgcgtcg caacagatcc agcacgagga cctctcccat ggccagtcgc aacccatcct
    69421 tcttccgccg catcggcctc gccttctccg tcctcttcgg cgccgagctc gccggccgcc
    69481 tcgtccgcct gcgcgagcaa gccacggatg ccgagccccc cgccacagcc ggcgccgagg
    69541 aagccgccgc gcccgcccgg cccgccatcg tccacgagac cacccccgag gccgcgctgc
    69601 agctgctcgg cctgctccag cgcgacgcgc gcttcatcga cttcgtccag gaagacatcg
    69661 gcgcgtactc ggatgccgac atcggcgccg ccgcgcgcgt ggtgcacgag ggctgccgca
    69721 aggtgctcga cgagcacttc gccatcgcgc cggtgcgcag cgaggccgaa ggcagccgcc
    69781 tcaccctggc tgatggcttc gacgccgcgg ccgtgcgcct caccggcaag gtggtgggca
    69841 agccgccctt caccggcacc ctcggccatc gcggctggcg cgtgaccgac acccgcctgc
    69901 cggcgctggc cgaaggccac gacgccagcg tgatcgccca ggccgaggtg gagctgtgag
    69961 cgcggcccgc tacaccctcg gcatcgacct cggcaccacc cactgcgcgc tgtcctatgt
    70021 cgacctcgag gccagcgacg gcgaccaggc cgcgcagcag gtgctggaga tcccccagct
    70081 caccggtccg ggcagcatcg agggacgccc gctgctgccc tccttcctct acctgccgca
    70141 cgccgacgag ctcgcccccg gcgacctgag cctgccctgg ggggcgacgc aggatcacgc
    70201 ggtgggcgaa ttcgcgcgca gccgcggcgc agcgacgccc atccgcctgg tggcgagcgc
    70261 caagagctgg ctgtgccacc ccggcgtgga ccggcgtgcc gacatcctgc ccgccgaggc
    70321 gccgcccgag gtggcgcgca tctcgccgct gaccgcctcg gtgcgctacc tgtcgcacct
    70381 gcgcgcggcc tggaacgccg cccatcccga ggcccccttc gacgcccagg acatcaccgt
    70441 caccatcccg gcctccttcg accccgccgc gcgcgagctc accgccgagg ccgcgcaggc
    70501 cgccggctac ccgcccgtca ccctgctcga agagccccag gccgcgctct acagctggat
    70561 ccagcgcagt gccgggcaat ggcgcaagga ggtgaagacc ggcgacctga tcctggtggt
    70621 cgacgtcggc ggcggcacca ccgacctgtc gctgatcgca gtgctcgagc gcgacggcaa
    70681 tctcgagctg caccgcgtgg cggtgggcga gcacatcctg ctcggcggcg acaacatgga
    70741 cctggcgctg gcctacacgg tcacgcgcaa gctggccgcg cagggcaccc ggctcgaccc
    70801 ctggcagacg cgcgcgctcg cccacgcctg ccgcgccgcc aaggaagcgc tgctgagcga
    70861 ctccgggctg gacagcgtgc cggtggtggt gccgagccgc ggctccaagc tcatcggcgg
    70921 ctcgatccgc accgaggtgc tgcgcgagga gctgaccgcc accctggtcg agggcttctt
    70981 cccccgcgtc gcggtcaccg agcaacccat cacgcgggcg cgtgccgcgc tcacccagct
    71041 cggcctcccc tatgcgcagg acgcggcggt cacccgccac ctcgccgcct tcctcacccg
    71101 ccagctcggc gccacttccg agctcgacgg cttcgccgtc cagcccgggg acgcgcactt
    71161 cctccacccc accgcggtgc tgctcaacgg cggcgtgctc aagtcggtcg tgatcgccga
    71221 gcgcgtgctc gacacgctca acgactggct cgccgccgac ggcgccgcgc cggcgcgcct
    71281 gctcggcggt gccgacctcg acctcgcggt ggcgcgcggc gcggcctact acggctacgt
    71341 gcgccgcggc cgcggggtgc gcatccgcgg cggcaccgcg cgcgcctact acgtcggcat
    71401 cgagtcctcg atgcccgcca tccccggcat ggagccgccg ctcgaggcgc tgtgcgtcgc
    71461 gcccttcggc atggaggagg gcagcgaggc cgccctgccc gagcaggagt tcggcctggt
    71521 ggtcggcgag ccggtgcgct tgcgcttctt cggctcctcg gtgcgccgcc aggacgaggt
    71581 cggcaccctg ctcgactggt ggaccgacga cgagctgcag gagctcgagg agatcgaggc
    71641 caccctgccc gccgaaggcc gccgccccgg cgaggtcgtg cgcgtcaagc tgcacgcccg
    71701 cgtcaccgag gccggcacgc tcgagctcga ggccctgccg gtggacggca gcgcgcgctg
    71761 gaaggtgcag ttcgacgtgc gcggcaccac cgaggcctga ggtccttcgc gtggcgacgc
    71821 gctacaccgt cggcatcgac ctcggcacca gcaacaccgt ggtcgccttc gccgccgccg
    71881 gcgaggaccg catccaggtg ctggagatcg agcagctcgt cggccgcggc gagctcgccg
    71941 cgcgcgcgct gctgccctcg gtgcgctacc accccgccgc gggcgagctc gaccccgcca
    72001 cgctgcgcct ggccgcaagc ctggcggggc tcgacgaggt ggacaaggcc gcggtgatgg
    72061 gcgcggcggt ggtcgggcag tacgcccgcg agctcggcgc ccaggtgccc gggcgcgcgg
    72121 tggccagcgc caagagctgg ctgtcgcacg ccggcgtcga ccgcagcgcc gccatcctgc
    72181 cctggggcgc ggccgaggac gtgcccaagg tctcgccggt ggtcgcgagc gcgagctacc
    72241 tcgcccatgt gcgcgcggcg tggcgacggc ggcaccccga ggccccgctg gaagaccagg
    72301 acatcgtgct cacggtgccc gcctccttcg acgagggtgc gcgcg
//
LOCUS       DAOTIN010000004        64475 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_407_length_64475_cov_9.774806, whole genome shotgun sequence.
ACCESSION   DAOTIN010000004 DAOTIN010000000
VERSION     DAOTIN010000004.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 64475)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 64475)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64475
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_407_length_64475_cov_9.774806"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(5..613)
                     /locus_tag="P5537_01150"
     CDS             complement(5..613)
                     /locus_tag="P5537_01150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HRV76679.1"
                     /translation="MPNVTAVMSTPNPLANKFMLDAPLYTGAPRHFRVGVPVVGDTLG
                     ESLLAVPGVVDIYCTGGFITITRDPGTPWSAIEPAVTELIEGHKARRVIGIANPAGPG
                     GAPGTASGGDEAAGEEAVEVEADDAELLMRINQILDEHIRPFLDQDGGGLDVVKLKEF
                     TLTVRYKGACGGCPSSSTGTLFAINNLLQSYVDDRLLVEPIY"
     gene            816..1397
                     /gene="rsxA"
                     /locus_tag="P5537_01155"
     CDS             816..1397
                     /gene="rsxA"
                     /locus_tag="P5537_01155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004377091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HRV76680.1"
                     /translation="MKEYLLLLLGTALVNNVILVRFLGLCPFLGVSGKLETALGMGLA
                     TTFVLTLTSGATWVVEHALLQPLDMMHLRILTYILVIAAVVQFTEMAIQKASPVLHHT
                     LGIYLPLITTNCAVLGTALLNLQQDNSLIQSLLYGAGSALGFTLVILLFAGLRERIAL
                     ANVPAAFAGTPIALITAGLLSLAFMGFAGLPVR"
     gene            1435..1974
                     /locus_tag="P5537_01160"
     CDS             1435..1974
                     /locus_tag="P5537_01160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HRV76681.1"
                     /translation="MTMILSVAVVAALGLGLGWLLGLASQWLGATTDPVVERLTEALP
                     GSQCGQCGYPGCGQAAIALSKGEAPVTLCPPGGRVVAEKLAEILGTTFDPGNLPDRGP
                     LLARVRTDYCIGCSRCIKSCPTDAILGATKQLHVVLEEACIGCGACAEVCPTGGIDLE
                     GIPVTLRNWRWHKPGVGHA"
     gene            2010..3455
                     /gene="rsxC"
                     /locus_tag="P5537_01165"
     CDS             2010..3455
                     /gene="rsxC"
                     /locus_tag="P5537_01165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004377096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HRV76682.1"
                     /translation="MKIFRFRGGIHPEGNKDPTACHPIARLPLPKRLYIPLQQHIGEP
                     AAPEVKVGDHVLKGQRLARHQGSVSAPVHAPTSGTVIAIGDHMAPHPSGLPVQTITLE
                     PDGEERWVETEPAVDPFSLTRAEVAARVRDAGIVGLGGAAFPAAVKLDAGNRHPIDTL
                     IINGGECEPYLTCDDRLMREGAGYVVEGVRLIANGLGAKRTVIAIEDNKPEALEAMRV
                     AAAAHPGISVLRVPSRYPMGSEKQLVTTVTGREIPAGKLSAEIGVSVHNVGTALAVCR
                     AVRFGKPLVSRVVTVGGGAIRNPRNVVVPIGTPAADLVEFCGGFTVTPTRVLMGGPMM
                     GQVLPGLEAPVVKGTSGIIALTAAEAHAASERACLHCGRCVDVCPVGLVPLELAARVR
                     AGRIDDAAELGMGDCLSCGCCAYVCPAHLPLAHLFNYAKGEIAARREAQRKAEETRKL
                     AEARRLRLAAEAAAKAARRPARTTEKAETES"
     gene            3452..4525
                     /locus_tag="P5537_01170"
     CDS             3452..4525
                     /locus_tag="P5537_01170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HRV76683.1"
                     /translation="MTTWTPNRSPVAAPHVHGRANVPQVMRTVLLALLPATATGVWLF
                     GWPALNTVLLAIAGCVAAEAAALAIGRRPVGHTLADGSAVVTGLILALCLPPWAPWWL
                     ALLGGVFAIVVGKQVFGGLGQNVLNPAMLARVALLVSFPLEMTAWVAPQPLFSAASPG
                     LVEGLAITFGGGPLPDAVSSATALAPLKLGGDFAAGEALLALALGTVPGSLGETSALA
                     LLAGGALLVARRIVPWQIPAALLGTLAVLAALFNQIDPAHYPGPLLHLLGGSAMMCAF
                     FIATDPVGAPVTPLGRAIFGAGIGALIYVIRTWGGYPEGVAFAVLLMNAATPLIDRLV
                     RPRRYGRLRTGAPLPLAPKEDGR"
     gene            4522..5172
                     /locus_tag="P5537_01175"
     CDS             4522..5172
                     /locus_tag="P5537_01175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HRV76684.1"
                     /translation="MSSTLAAGLRRRPGLLLGAFALGCSAMLGAGDLATREEIRQRQA
                     DDLRHALDQTLSAVPHDNNPAEDTIAVEDAGRSVTVYRARMAAEVNGVAFNWVSEAGY
                     GGPITLTVGIGRDGRIASVRVLSHSETPGLGDKIDVRKSDWIRGFDGRGLDTGTRWGV
                     RKDGGEFDQFAGATITPRAVVGAVHASLKFFAAHREHLLAAPAGAAAAAAQPGSPT"
     gene            5169..5843
                     /locus_tag="P5537_01180"
     CDS             5169..5843
                     /locus_tag="P5537_01180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit E"
                     /protein_id="HRV76685.1"
                     /translation="MSEVRRVVRDGLWDNNVVFAQMLGMCPTLATTGSATNGLGMGLA
                     TTVVLVCSGVLVSLFRNVIAREVRIAIYVLLMSTVVTLVDMTMNAWLHELHKVLGLFI
                     PLIVVNCAIMGRAESFASKRAPGMAALDGLMMGVGFTLALMVLGGVREAIGQGTLFAD
                     ASMLLGEHFAFLELRLDGYRGVLLMILPPGGFLALGFLVAARQRMLARARARSEGAGA
                     AMTAGT"
     gene            5896..6192
                     /locus_tag="P5537_01185"
     CDS             5896..6192
                     /locus_tag="P5537_01185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018989082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfH family protein"
                     /protein_id="HRV76686.1"
                     /translation="MKISVSYAHPEKPAWVRLDVEEGCTLRAAIERSGILGRYEDIDL
                     TRNKVGVFGKIKPLDTVLAEGDRVEIYQPIVIDPKTAPRRKRAEAGDGDGAEEG"
     gene            complement(6259..6801)
                     /locus_tag="P5537_01190"
     CDS             complement(6259..6801)
                     /locus_tag="P5537_01190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HRV76687.1"
                     /translation="MRGMRTSRRASGARRERCRSGHRDTENEMNEEIAGKAVRMRESA
                     NATTYTISDLAKEFDITTRAIRYYEDQGLISPARRGSRRIYSRRDRVRLSLILRGKRL
                     GFSLQETRELFDLYDNAPGEQAQMSHFMELLGARRAMLERQMEDIRAILDEIDAAEKE
                     ARRSIAARALEPIPAMSPSA"
     gene            complement(6908..7570)
                     /locus_tag="P5537_01195"
     CDS             complement(6908..7570)
                     /locus_tag="P5537_01195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HRV76688.1"
                     /translation="MARGKAPTFQVQRATILDAAAGLFAARGFHHASMAEIARECGVS
                     KALLYHYYRDKEHILYDIAAGHVEELLAIVAEVEAAAAAPRERLERLILRFMQAYEGG
                     RRQHVVLIQDVKFLSPEQRARIHEQERRVVRAFALTIEAVEPGLRGVALDKAVAMVLF
                     GMMNWTFTWLRPEGTLSYEALARVVARVFVRGIAGLATEAVQAPAGGSEAALPRGVCE
                     RS"
     gene            7899..8507
                     /gene="paaY"
                     /locus_tag="P5537_01200"
     CDS             7899..8507
                     /gene="paaY"
                     /locus_tag="P5537_01200"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetic acid degradation protein PaaY"
                     /protein_id="HRV76689.1"
                     /translation="MPCYEIDGVRPVVHPTAYVHPDAVLIGDVFVGAGCYVAPLASLR
                     GDFGRIVLEEGSNVQDCCVLHSFPGIDTVVEANGHVGHAAVLHACRVGRNALIGMNAV
                     VMDHAEVGEGSIVAAAAFVKAEMKIPPGVLVAGVPAKVLRELTEQERKWKVIGTECYQ
                     NLARRSLATLKPCDPLREGDRERPRFEAPDVMPLSDARRRTD"
     gene            complement(8589..9527)
                     /locus_tag="P5537_01205"
     CDS             complement(8589..9527)
                     /locus_tag="P5537_01205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HRV76690.1"
                     /translation="MSLRDFDLNLLRILLAVYEAGSVSRAAQALGLSQPTVSSALGRL
                     RRALGEPLFIKTASGVTPTARTHALASSARAMLARLEADFFVADRFDPARYEGNLTVA
                     LSDVGEMVFLPRILDSVRRIAPLAMLDSVTLAPGELMRAMEDGEVDLAIGYHPDLDAA
                     GFYREKLLSHRFVCLLRADHPVQDHQLSLECFLSLEHAAVRAKGRSQEIFEKYLERLR
                     IQRRIVLRTPHFMSLPGIIGRSDLVVTLPHAIGQYFTRVGERVRMAEPPLAIPRIELF
                     QHWHRGFHHDPRNRWLRTLVAGLFSEEQDEWPYPFA"
     gene            9742..11175
                     /locus_tag="P5537_01210"
     CDS             9742..11175
                     /locus_tag="P5537_01210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HRV76691.1"
                     /translation="MNAAEWLLGGEPARIALIEGDVRIDYAGLRADAMRSAAALLDAG
                     LRPGDACVLALPDGIEWATAFIGMLWAGVRPIAINPRTASEQIADLMLDSGAAAALLE
                     DGAARALGDKRAIALGEWRRRVERATATPAAAPAADDDPAFLLYSSGTTGRPKGILHA
                     HRAIRDAHVFARDILGARPEHRFYSSSKLFFAYPLANAFFAGLRLGATVVLDPEWPDP
                     ARVAAMVERHQPHIFFSVPTLYRRLVDAGVRFRGLHAAVSAGEACPPALAREWQAMTG
                     VPLVNGYGTTETLSLVLYRTPEMESAHPTPLTTIHPEQLTSGEVETWRLWFAHPAVAL
                     GYSRVVTHDSARFADGHFAPGDVFRRAPDGEGWLFAGRSDQLVKVFGRWVDVVAVEQA
                     VQERMRGKAEEVCVIPAQGEDADMIRLHLFAIPGDLPPPQVLAAAQAAIESLPPYQRP
                     EKIHLVDHFPRTDTGKLRRNELARHTG"
     gene            complement(11209..11532)
                     /locus_tag="P5537_01215"
     CDS             complement(11209..11532)
                     /locus_tag="P5537_01215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HRV76692.1"
                     /translation="MKVIVDLCVVPLGVGLSVSAHVAACERVIREAGLKSQLHAYGTN
                     IEGEWDEVMAAVKRCHEVVHAMGAPRITSSMRLGTRTDREQTMADKIASVERALDSAA
                     SGPGA"
     gene            complement(11569..12165)
                     /locus_tag="P5537_01220"
     CDS             complement(11569..12165)
                     /locus_tag="P5537_01220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HRV76693.1"
                     /translation="MLLNKPFGVLCQFTDEAGRRTLKDYVAVPGIYPAGRLDADSEGL
                     VLLTGDGALQHRIADPRHKLAKRYLVQVDGEIDEVALVLLRAGLDLGDFRTQPCAARR
                     IPEPDWLWPRDPPVRFRKSVPTSWVEIVLREGKNRQVRRMTAKVGHPTLRLVRVAIGP
                     WCLDGLGVGEWREVAREEVGVVLAGGGTAAVRGNRLRR"
     gene            12458..12613
                     /locus_tag="P5537_01225"
     CDS             12458..12613
                     /locus_tag="P5537_01225"
                     /inference="COORDINATES: protein motif:HMM:NF019225.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-CTERM sorting domain-containing protein"
                     /protein_id="HRV76694.1"
                     /translation="MRTLLSIAVLSALSAPAFAFPNSQPLPEPETLALIAVGLVGVLA
                     SRLRNKK"
     gene            12716..>14825
                     /locus_tag="P5537_01230"
     CDS             12716..>14825
                     /locus_tag="P5537_01230"
                     /inference="COORDINATES: protein motif:HMM:NF028519.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdrD B-like domain-containing protein"
                     /protein_id="HRV76695.1"
                     /translation="MSTSRILSIKVTYPDQFLEPSTFDLQFLGASDFGSGYYDAWCAD
                     ADIPLDVVGPVNGVYSLTLKAGLYSSYDYGAIPAAFQSIELPGHLDEANWLLNQHFTV
                     GASPYTTNEVQAALWTLLGDQDRVATLLPGTDATRVQTLVDLALQNDGFAPDITDDNP
                     NNDEIGLLLDLWKDSNNNGVRDANEVVQQPLIVMVKSAALGDRVWHDVNADGIQNVGG
                     DGAYTEQGIAGAVVRLVHDRDGDGAFTSAGEVLATTTTDADGNYVFKGLAPGLDYQVQ
                     FFTPTGFDAASPRQQGASNAADSDGALSDVVVLSAGEWNKTIDAGFYKPVSVGDFVWN
                     DQDADGIQDVGEAGIGGVRLTLTGTTGSGEVIVRNTLTAADGSYLFDALPPGIYQVSV
                     DADNFDPAGALSGFQSSPIGQGTDAALDSNASPTGTDPVTLLSGQSDTDLDFGYFKAT
                     AAIGDRVWEDTNANGQQDDGETGIADATVRLYTCVDGAPGTLVATTTTDASGNYAFTG
                     LVPGQYIVAFETPAGYQLSTADVGADASDSDAGTGGLTGCYTLASGETNNTVDAGFWR
                     PAAIGDRVWLDANANGQQDDGEAGVEGVEVELYTCVDGAPGVKVGASTFTDAAGNYAF
                     TGLMPGQYVVKFLTPDGFSLSPVDVGGDGSDSDAGMGGFTGCYTLTSGQTNNTVDAGL
                     YQGAAIGDRVWEDTNANGQQD"
     assembly_gap    14826..14925
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <14926..19601
                     /locus_tag="P5537_01235"
     CDS             <14926..19601
                     /locus_tag="P5537_01235"
                     /inference="COORDINATES: protein motif:HMM:NF028519.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="SdrD B-like domain-containing protein"
                     /protein_id="HRV76696.1"
                     /translation="KVGASTFTDAAGNYAFTGLEPGDYLVKFITPTGFFLTNQNVGAN
                     DTADSDADATTGFTGCYKLEAGETDSTADAGIFKPGEGGVVASIDLVKLTNGTDNNAP
                     TGPYLAVGSTATFQYLVTNDGMVALSDIVLSDDHGTPGDTSDDFTPIFLGGDADGDGL
                     LDVGESWIYEASTVVSAGQYTNLGAVTGTPVDADGNLVPSLPQPTDTDLDNHFGARVA
                     IDIEKFVRGVHQDTGGGGEGLTPGFWKTHSEYGPAPLAGWPETGYSPDDAWEAVFGIN
                     VPGAPTLLDALNAAGGGLDALLRHSSAALLNAAQPNVDYAYTSSQVISLTRDAILSGD
                     LNQIESVKNQFVMQNELGADLSTPASGGATVTTPWFDADAPGTGPFIALGGTAEFRYE
                     VRNTGDVALEGVSVSDDRLSGLSFEGGDTDHDGLLDLDEVWVYRGSELADTAGVDIAN
                     VGTATGSALGIMATDADAARYSTAASTQSLGDFVWLDANRNGLQDGGEAGIGGMLVTL
                     TGGGADGIINGVGDTTAITSTDVDGYYQFDNLAAGVQYQVTFGKPAGTAFTMRDAGAD
                     DAIDSDAGADGKSQIVTLSPGQHNPSVDAGVYVLNPGIDLEKTTSGPSNANPTAADYD
                     NEDTPDGAGVPVLTAGSAVTWTYKLTNTGNVDFAKADLALVDDNGTPTNAADDMSIAN
                     GKIAYVSGDDGDNVLEAGESWLYEAHGTVQSLGVLGAATTIDFSGNTAVDGTDGNTRS
                     YSAGGVTVQANAWSRTKGSDTWQKAWLGAYDAGLGVTDSSESGSGSTHTVDNYGRDNY
                     IVFQFSQDVVVDKAFLGYVVGDSDMTVYVGSSTAPITAMNNAVLAGMSLKEFNDTGST
                     SARWADFNAGDVQGNVLILAARDDGHSSDYFKVEKLVFEAVQSGGVYANTATVTAPGG
                     LSDSDMSHYETVPATPGIDLEKTTSGPSNANPTAADYDNEDTPDGAGVPVLTAGSAVT
                     WTYKLTNTGNVDFAKADLALVDDNGTPTNAADDMSIANGKIAYVSGDDGDNVLEAGES
                     WLYEAHGTVQSLGVLGAATTIDFSGNTAVDGTDGNTRSYSAGGVTVQANAWSRTKGSD
                     TWQKAWLGAYDAGLGVTDSSESGSGSTHTVDNYGRDNYIVFQFSQDVVVDKAFLGYVV
                     GDSDMTVYVGSSTAPITAMNNAVLAGMSLKEFNDTGSTSARWADFNAGDVQGNVLILA
                     ARDDGHSSDYFKVEKLVFEAVQSGGVYANTATVTAPGGLSDSDMSHYESAAKIVAAPK
                     FFVVDQAKDLSYQYADGGDGLGSFALANTDPRDIAANADGSLLWVLDRDKNVEVYKGD
                     GTQLGQWKAYGLGTEPEGITLDGKDLWMADRTGKLNWYDNAATRTSGTDSPELSFTLS
                     LDGNLKGIVTDGTYLWAVTEGTCDYVYRFKIVRDWWGNPSGLSQSGGWQLPTANTKPT
                     GITLDPSGKSDSLWIVDESTDTVYEYGYGRSQTWGVGTITAKFKLSAGNTAPQGIADP
                     LPAGAEAFDLAEISAAAGLETTQPDPYAGDFVTPLFDDAIAFHDAGIVGTSAQSEATL
                     ALLHA"
     gene            19762..21555
                     /locus_tag="P5537_01240"
     CDS             19762..21555
                     /locus_tag="P5537_01240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I secretion system permease/ATPase"
                     /protein_id="HRV76697.1"
                     /translation="MTKQTFGQPAGGELKEALQALRNAFTTVGAFSGFINLMMLAPAL
                     YMLQVYDRVLGSRNETTLVMLTVLVVGALLFMAALESVRGWILVRVGARLDAQLNGRV
                     FTAAFERNLQQAGSNTAQPIHDLNAVRQTLTGSALLAAFDAPWLPIYLVVIFMMSPLL
                     GWFALAGAIVLLVLAVANERISKPRLDEAQKFSMQSHQALVSHLRNSEVIEAMGMLPA
                     IRQRWHALHRQQIHAQALASDRAAMLSGATKFVRIAMQSLILGFGALLVLEDQITAGM
                     MIAASILLGRAFAPIELLVGNWKQIVSGRQAYARLQELLQRHPARGTSMSLPRPQGRI
                     TAEGVSAMPPGTRRMVLKNLGFTIAPGEVVAVVGPSASGKSSLARLLVGVWAPAAGSL
                     RLDGASVYDWNKDELGPALGYLPQDIELFDGTVAENIARFGEVDSERVVDAARKVGMH
                     EHILHLPQGYDTPLGAEGSNLSAGQRQRIGLARALYGDPALIVLDEPNSNLDEAGEKA
                     LLEALLGLKARGATVVIVTHRMSTLAAADKVMVLTDGTLAAFGPRDEVFKPTPATTTA
                     PSTPNATPANRRVANVVPGAPVLAPGAAPGR"
     gene            21615..22964
                     /locus_tag="P5537_01245"
     CDS             21615..22964
                     /locus_tag="P5537_01245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030253 - protein secretion by the type I
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family type I secretion periplasmic adaptor
                     subunit"
                     /protein_id="HRV76698.1"
                     /translation="MPPSPPDSSAPPGGQSGSAAHTELSDSHARRWGWLLVVAGFGGF
                     MAWAALAPLDSGVAAPGTVVVSGNRKAVQPLVGGKIAELAVRDGDAVRAGQVLVRLDD
                     TQARSQLDVARGQWFTASAVEARLVAERLGHPQIEFPAALREAHADPRASAAMALQRE
                     LFVTRQRALASELAILEESIRGLEAQLRGVEASSHARRTQVGLLRDEIARQRGLVDEG
                     FYPRNRLSEQERSLAALNAAIAEDAGNAGRIRQQIAETRSRMIARENQQRQEVESQLT
                     EVQRDAGALLSRIEALEFDLRNTEIAAPADGLVVGLAVHTVGGVVGVGNPLMEIVPAD
                     EPLKIDAQIPPHLIDHVRAGLEVDILFPAFNRATTPNVAGRVLQVSADVLVEPQQGIQ
                     YFKAVIEVTAEGMHKLRQYEIRPGMPAEIFVRTGERTLLNYLVKPLTDRLKGALTEP"
     gene            22961..24313
                     /locus_tag="P5537_01250"
     CDS             22961..24313
                     /locus_tag="P5537_01250"
                     /inference="COORDINATES: protein motif:HMM:TIGR01844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family outer membrane protein"
                     /protein_id="HRV76699.1"
                     /translation="MMRIDSRPLALVLALALTPAPALAAGAFATAFDAARANDAAYRA
                     ARHELEAGETLVPIARAGLLPSVTASFSESRVRGEREYAPPRPKDDLDYRNPVFALQL
                     RAPLFNLEAYSRYAAAQAQTEGARARFAAGGRELLDRLGLAYVQRLFAEETLALARVQ
                     VDALETQTTIARRRLGAGEGTRTELADAEASLASARAERIAAEDQRELTQRALARITG
                     SEALALRALPAHAAPLLPATRALSEWIALAREHNPTLATREREIEALEHEIRRNRAGH
                     YPRVDLVASAVNAENESISTLDQETRQYSVGVQVNIPIYAGGGVDASVRRAAAELARA
                     QARLDDDLQSLQLDVERQFRTIESGRARLAALDDAVASSELALQGARRGQSAGVFSSA
                     DVLDALRRHHSARRDAAQARHELLIARIRLQALAGIAEEEIVADVDRLLTAELVADRR
                     "
     gene            complement(24389..24478)
                     /locus_tag="P5537_01255"
     tRNA            complement(24389..24478)
                     /locus_tag="P5537_01255"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(24442..24444),aa:Ser,seq:tga)
     gene            complement(24536..25861)
                     /gene="rlmD"
                     /locus_tag="P5537_01260"
     CDS             complement(24536..25861)
                     /gene="rlmD"
                     /locus_tag="P5537_01260"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HRV76700.1"
                     /translation="MPIAKIDSLDHEGRGVTRVEGKAVFVEGALPGERVEYVVRRAKP
                     SYEQGETVRVLRPSAQRVAPRCPHYGVCGGCSMQHLDADAQAAVKQRILEDALRHIGK
                     LRPGRILPAIHGPAWGYRYRARLGVRMVPSKGGLRVGFHERRSSYIVDMRTCPVLPLA
                     ISALLPRLRTMLAGLSIADRLPQVEIAVGEDSTVFVFRNLLPFSAADEKRLAAFADAE
                     GIQAWIQPAGPDSARPLHPAGAQSPFYTLPEFGLRLDFRPTDFTQVNVDINRLLIRRS
                     MQLLDPRPGERIADLFCGLGNFSLPIARLGAEVVGVEGSEALVERAHANAARNGLAAL
                     CEFHAANLFETTEDSLAALGRLDKLLIDPPREGAIAVVKAIDPSRGPARIVYVSCNPA
                     TLARDAAVLVHEKGYRLAAAGIANMFPQTSHVESVALFERASEGLAGQG"
     gene            26210..26560
                     /locus_tag="P5537_01265"
     CDS             26210..26560
                     /locus_tag="P5537_01265"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76701.1"
                     /translation="MKESAAQAVEAAKESAKAAGDAAAAGAQAVKQEAAVAVEATKEA
                     AATAADKAAAAADAAAQKADAVADAAAQKAGAAVEAVKDAAAEAKADTVDAAAQAKAA
                     AEAAVSAAKESAAK"
     gene            complement(26692..27837)
                     /gene="bamC"
                     /locus_tag="P5537_01270"
     CDS             complement(26692..27837)
                     /gene="bamC"
                     /locus_tag="P5537_01270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamC"
                     /protein_id="HRV76702.1"
                     /translation="MIRSKRTSLSLLALSIALGGCSGSLLESKRIDYKSAKQIERPLE
                     IPPDLTAPQRDDRFAVPDVAPRGVATYSAYTADRASQPAQVSSGPEVLAKSDTMRVER
                     AGSQRWLVVGGTPEELWPQIKDFWLELGFILNIDSPEIGVMETDWAEDRAKIPQDFIR
                     SSIGKVFDGLFSTPERDKFRTRLEQGKEAGTVEVYISHRGMMEIYPTEAKDSTIWQPR
                     PADPELEAEMLRRLMVRLGAEEVRAEAAIATPQQASERARIASASDGQVMLVMDEAFD
                     RAWRRVGLALDRIGFTVEDRDRAQGLYFVRYVDPDADNRSPDKGLLSRLAFWRSDDKP
                     AAGGSEYRLRVQGQGDASRVSVLTREGGLDNSETARRMLGLLQEQLR"
     gene            complement(27864..28742)
                     /gene="dapA"
                     /locus_tag="P5537_01275"
     CDS             complement(27864..28742)
                     /gene="dapA"
                     /locus_tag="P5537_01275"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HRV76703.1"
                     /translation="MITGSLVAIVTPMHDDGSLDFPRLRSLIDWHIAEGTDGIVIVGT
                     TGESPTVTVGEHCELIRVAVEHCAGRVPVIAGTGANSTAEAVELTRFAAQAGANAHLS
                     VVPYYNRPTQEGLYRHFRTIAEAVELPLILYNVPGRTVADLANDTVLRLAEVPNIVGL
                     KDATGNLDRACDLIERAPADFALYSGDDMTSAAFLMLGGHGVISVTANVAPRAMHALC
                     AAAAAGDMRTLRETNAALTGLHRDLFCEANPIPVKWAVARMGLVGDGIRLPLTPLSAA
                     HHERVRAAMRKAGIQA"
     gene            complement(28885..29811)
                     /locus_tag="P5537_01280"
     CDS             complement(28885..29811)
                     /locus_tag="P5537_01280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004336413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histone deacetylase family protein"
                     /protein_id="HRV76704.1"
                     /translation="MTTTAFITHRDCWLHDMGAMHPECPDRLSAINDRLIASGLDMYV
                     SFFDAPLAEREHILRVHPAEYFDNLLESVPEHGIRHLDPDTAMSPGTMKAALRSAGAG
                     VYATDLVMKGEIENAFCAVRPPGHHAERAKAMGFCFMNNVAIAARHALEVHGLERVAV
                     VDFDVHHGNGTEDIFRNDPRVMMAGIFQHPFYPYCGTENPPAHMCNVPLPAGTRGDAF
                     RQVFGDIVVPALRSHSPQMIFISAGFDAHYEDDMGSLGLLEADYIWATQQIKGVAEAC
                     GHKRIVSVLEGGYSLSSLARSVVAHIKTLADL"
     gene            29966..30883
                     /locus_tag="P5537_01285"
     CDS             29966..30883
                     /locus_tag="P5537_01285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HRV76705.1"
                     /translation="MPLHHANRLLEAASRIILGKERELRLALACLIARGHLLIEDVPG
                     VGKTTLAHTLARLMGLQFQRIQFTSDLLPADILGVSVFDRDTAAFRFHPGPVFSQLIL
                     ADEINRATPKTQSALLEAMEERQVTADGQTCALPEPFFVIATQNPAHQVGTFPLPESQ
                     LDRFLLRIRLGYPDPQAERALLMGEDRRGLLERHQAVIGPAELLEMQQAAQGLHVAEA
                     LVAYVQALLAATRNSAELAGGLSPRAGLGLLAAARAWALLDGRDHVLPEDVQALFPHV
                     AAHRVHLAGDGRPVPPATLLRLLQAVAVG"
     gene            30883..31890
                     /locus_tag="P5537_01290"
     CDS             30883..31890
                     /locus_tag="P5537_01290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HRV76706.1"
                     /translation="MARLITTAFVQRLRHSVDRWLFRVGAAEPAPIRLGQRRIYVLPS
                     AAGIAFALALLVMLLAAINYNLSLGYALVFTLGGSAASSMLHAFRNLYGLSIRPGRCP
                     PVFAGDTAVFTLLVDNPAPRRRPALRLGAQGQCSSFELPAAQETAIPIACPAPRRGRL
                     VLGRSTLETRWPLGLIRAWSVFVPAAECLVLPTPEADPPPLPRDGAGDTAPGSRRTGE
                     GDDDFAGLRAHRSADSPRHVAWKVLARGGPMLTKEFAAGQGRELLLDWDHLPPGFDDE
                     RRLSRLTAWVLAAEREGLRYALALPGVRIPAAAGGAHRERCLRQLALHGLADATAGEQ
                     A"
     gene            31887..33905
                     /locus_tag="P5537_01295"
     CDS             31887..33905
                     /locus_tag="P5537_01295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011764826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3488 and transglutaminase-like
                     domain-containing protein"
                     /protein_id="HRV76707.1"
                     /translation="MSTARSSRRLGLFRHGGALPRERVTPPAPTLRRNQGAWLLGAAA
                     MAIAPHSVWLPAWITALGLALLAWRALLLWRGSRPPPGVLLFALALAVAAGVRLEFGH
                     FFGREPGVAVLVLLLGLKLLETRAARDIRAAVLLCLFLQLALFLEDQSLPVAALVLGG
                     TLLALGALVALADPDGSQREHLRTAAALLAQGIPFMLVLFVLFPRIQGPLWGLPADAF
                     SARTGLSETMRPGSISVLGQSEAIALRAAFSGPPPPPAQRYWRGPVLSRFDGREWRAE
                     AVVESASPAYPLQGERIDYLLTIEPHQRRWLLALEHPGSAQPAIRYTSDLRALAAEPL
                     RARARFALGAYPQTQAGVEESPAVLAAATALPADSNPRSRELAAELATGARDHAEILE
                     RVLARLRGLRLAYTLRPPLLGRHTADEFLFDTRRGFCEHFASAFAVLMRAAGVPTRIV
                     TGYQGGELNPIDGHLVVRQSDAHAWAEVWLQGRGWLRVDPTALAAPERIDGGLAAALA
                     GAGELPFMLRTDMVWLRDLRHRWEAVANLWNQQVLGYNPERQRELLARIGLGADRLAR
                     TLGVLAGAAVLLLAALYGWSLRGARTRDALAREWERFCARMAACGLPRPPWQGPLDYA
                     EALAAHFPAHARELREICVLYASLRYGPHAPEEDLRTLENRIASLRLK"
     gene            33902..34987
                     /gene="mltB"
                     /locus_tag="P5537_01300"
     CDS             33902..34987
                     /gene="mltB"
                     /locus_tag="P5537_01300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lytic murein transglycosylase B"
                     /protein_id="HRV76708.1"
                     /translation="MNSTSHQTSRAAAAPPAATRIRPLGKLVTALALAIALGTPAAAH
                     ASYAGREDARTFAAEIASRHALDATEIERALAGARHDPEVIRLITPPTRKGVRSWHSY
                     RARFLDRTRIDGGMRFWREHADTLARAERETGVPAEVIVAIIGVETIYGRNTGNFETL
                     STLATLAFDYPPRAELFRRELEALFLLAREQGRDPASYYGSFAGALGYPQFLPSSMRA
                     YALDFDHSGAIDFESDPIDAIGSVANYLRAHGWQAGAPVAERARLSPATDTASLVAAG
                     IEPTLAPAVLADNGVTTADGRTAAAVATLVDLETPGSGTEYWLGYRNFYVITRYNRSS
                     FYAMSVFELAEALRLGRLVEEIRAERR"
     gene            34999..35772
                     /locus_tag="P5537_01305"
     CDS             34999..35772
                     /locus_tag="P5537_01305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004376544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2189 domain-containing protein"
                     /protein_id="HRV76709.1"
                     /translation="MPASAPPPTVDQTTLHPAPLGLADLGGALRFGLAQFRAIPMLSM
                     AFALLFVAIGALMFGLLEFGAIAPMSLSLAGGFMLVGPILLAGFFGVSDKLRKGRNPS
                     FGDIWSGFRQMPRGGWVVSFVCGLLFLIWITDAGILYGFMVGREPIGFLRLLRIEQVV
                     LDYAGYSAIMGGVLAFILFAASAFSIPLIYDGRATLVSGVVASVRAVFGRFGVMMCWA
                     FLLAAVIMGSIMALPLLLVSLPVMAYASRELYYRVFPLA"
     gene            complement(35791..36729)
                     /gene="rpoS"
                     /locus_tag="P5537_01310"
     CDS             complement(35791..36729)
                     /gene="rpoS"
                     /locus_tag="P5537_01310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011236260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoS"
                     /protein_id="HRV76710.1"
                     /translation="MEEPGNLDELERQQEPDLPPEVEVFSFQAPPVVENEFFSDVTQL
                     YLNEIGANPLLTAEEEGVIARRVRMGDFDARQTMIERNLRLVVNIAKHYLNRGIPLLD
                     LVEEGNLGLMHALEKFDPERGFRFSTYATWWIRQNIERAIMNQSRTIRLPVHVVKELN
                     QVLRAQRHIEADCNGESSLEQIANRLGKTIEEVRSILALGEHTASLDAPLDIDPTLSI
                     GESLADEHQASADVQIQCSEVEQLVREWLAMLNDKQRMVIRHRYGIDECELLTLEELA
                     ERLELTRERVRQIQLEALGQLRRILRRRGIPRDALL"
     gene            complement(36741..37571)
                     /locus_tag="P5537_01315"
     CDS             complement(36741..37571)
                     /locus_tag="P5537_01315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HRV76711.1"
                     /translation="MHKNIPSLIALLAAALLAGCASQGTAPVRDGSGVSSAPAASVSP
                     STGYHTVRPGETLLGIARQYGVTLPDLVSWNRITDPDQIHVGQTLRVSPSAAAGAIAG
                     SGGAVVTPVPATGSLAGTVPTVREPVGGRAPVAEPAPVEASPPVAVETPPSAVGGQWK
                     WPASGTVIAGFNESSNKGLDIGGAVGEPVYAAAAGKVVYAGSGLRGYGKLIVIKHNQE
                     YNSVYAHNDKLLVKEDDQVTQGQKIAELGSSEADRPKLHFEIRKQGKAVDPTGYLPAR
                     "
     gene            complement(37587..38234)
                     /locus_tag="P5537_01320"
     CDS             complement(37587..38234)
                     /locus_tag="P5537_01320"
                     /EC_number="2.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004719 - protein-L-isoaspartate
                     (D-aspartate) O-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-L-isoaspartate(D-aspartate)
                     O-methyltransferase"
                     /protein_id="HRV76712.1"
                     /translation="MRSSDPGQASRARARMVERLRAQGIRDERVLAAMQAVPRHAFVD
                     EGLAFSAYDDTPLPIGFQQTISQPFVVARMLELLRSGRELGRTLEVGAGCGYQAAVLS
                     LLATEVYAVERIRGLLDRARANLRPLRLPNVRLKLADGSLGLPEAAPFDSIIVAAAAS
                     GLPPALKEQLAPAGRLIIPVGGAEQRLLLIERQGNTFRETWCEAVRFVPLIAGTD"
     gene            complement(38237..38980)
                     /gene="surE"
                     /locus_tag="P5537_01325"
     CDS             complement(38237..38980)
                     /gene="surE"
                     /locus_tag="P5537_01325"
                     /EC_number="3.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004376553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008252 - nucleotidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'/3'-nucleotidase SurE"
                     /protein_id="HRV76713.1"
                     /translation="MRILVSNDDGYFAPGIAALAEALGTIGEVTVVAPERDRSGASNS
                     LTLDRPLSLRRTSNGFYHVNGTPTDCVHLAVTGMLDHLPDMVVSGVNHGANMGDDTVY
                     SGTVAAATEGFLLGVPSIAVSLVSKSATDFTAAARVARDLAERFMHNPFPRPVLLNVN
                     VPDVAYERLQGIRVTRLGKRHKAEPVVRSETPRGETVYWVGAAGGAADAGEGTDFHAV
                     ANGFVSVTPLQIDLTHTGLIAPVFDWLQR"
     gene            complement(39131..39207)
                     /locus_tag="P5537_01330"
     tRNA            complement(39131..39207)
                     /locus_tag="P5537_01330"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(39171..39173),aa:Pro,seq:ggg)
     gene            complement(39292..39672)
                     /locus_tag="P5537_01335"
     CDS             complement(39292..39672)
                     /locus_tag="P5537_01335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HRV76714.1"
                     /translation="MQASSPEPGGEQLPPIPAKRYFTIGEVSELCCVKPHVLRYWEQE
                     FTQLKPVKRGGNRRYYQHHEVMLIRRIRQLLYQEGFTISGARNRLGESAIQEQENGVE
                     LEQCKAMLRELRAEITATLQELRA"
     gene            complement(39653..39958)
                     /locus_tag="P5537_01340"
     CDS             complement(39653..39958)
                     /locus_tag="P5537_01340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit alpha"
                     /protein_id="HRV76715.1"
                     /translation="MTLTKAELADLLFEQVGLNKREAKDMVEGFFEEIRTALERGDSV
                     KLSGFGNFQLRDKPQRPGRNPKTGEEIPITARRVVTFHASQKLKAAVEQLSDASKQP"
     gene            complement(39960..42350)
                     /gene="pheT"
                     /locus_tag="P5537_01345"
     CDS             complement(39960..42350)
                     /gene="pheT"
                     /locus_tag="P5537_01345"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009328 - phenylalanine-tRNA ligase
                     complex [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HRV76716.1"
                     /translation="MQFSEQWLRTFVDPQLDSAGLGHLLTMAGLEVEEAEPAAPAFRG
                     VVVARIVEAEKHPNADKLKLCKVDAGTGELLQIVCGAPNAAAGMKVPCAVVGAVLPGE
                     FEIKKAKLRGVESFGMLCSARELGFSEDHSGLYALPEDAPVGTDIRAYLGLDDTLFTI
                     KLTPNRADCLSLTGVAREVAAITGGEFRALAIEPVSPSIDARRDIVLDAPQACPRYCG
                     RILRGVDARAATPDWMARRLGRSGIRSISALVDITNYVMLELGQPLHAFDNTKLQGAI
                     HVRLPRAGEQVLLLNEQTVTPAADTLLIADEARALALAGIMGGEDSGITLDTTEVFLE
                     SAFFAPDAIAGRARGYGFGSDASHRFERGVDPELARGALERATRLVLELCGGEAGPVV
                     EAVATDALPVRAPVRLRPARARRVLGIVLDDDDMLGLLRRVHLQVDRSGDDFLVTPPS
                     WRFDIEIEEDLIEEIARLHGYDNIPAVAPQGSLMMLPSTENGRPVWALRHLLAARGYQ
                     EVVNFAFVEEAWERDFCANENPIRLANPIASHLSVMRSSLIPGLVGTLAANRKRQIDR
                     VRVFEVARVFERKADGEPVHGFHQVMNIAALAAGQVVPEQWGERARNVDFYDVKGDLE
                     ALFAPRALQFTPLSHPALHPGRAAAVRLDGHMIGVLGELHPVWVQRYELGSAPVVFEV
                     ALDAALAARLPAYAEISRMQAVRRDLALVVGNDLPVERVLEVLREAAPEIVREIALFD
                     LYQGRGIDPDKKSLAFKVSMQDTRRTLEDAEVDAAIALLVAHAETVLGARLRGAGA"
     gene            complement(42400..43431)
                     /gene="pheS"
                     /locus_tag="P5537_01350"
     CDS             complement(42400..43431)
                     /gene="pheS"
                     /locus_tag="P5537_01350"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009328 - phenylalanine-tRNA ligase
                     complex [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HRV76717.1"
                     /translation="MEQLDQLVQLAAAEFAAAADGAQLEQAKARYLGKAGALTERLKA
                     LGKLEPEARREAGAAINAAKTAIEAALEGRRNALREAALLAQLAAEALDVTLPGRGGV
                     QGGLHPVSRTLERVERLFGSIGFVVADGPEIETDWHNFTALNTPENHPARSMHDTFYL
                     EGHDDVLLRTHTSPVQIRAMQAHVERHRDADAMPDLRIIAPGRVFRVDSDATHSPMFH
                     QVEGLWVGETVSFADLKGVIADFLRRFFETDDLQVRFRPSFFPFTEPSAEIDVAFMSG
                     ALEGRWLEIAGCGVVHPNVLRFGGIDPERYTGFAFGMGPDRLTMLRYGVNDLRLFFEG
                     DLRFLGQFR"
     gene            complement(43585..43944)
                     /gene="rplT"
                     /locus_tag="P5537_01355"
     CDS             complement(43585..43944)
                     /gene="rplT"
                     /locus_tag="P5537_01355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004192938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HRV76718.1"
                     /translation="MPRVKRGVTARARHKKVLSQAKGYRGRRKNVYRIAKQAVMKAGQ
                     YAYRDRRQRKRQFRTLWIARINAAARELGLTYSVFMNGLKKAAIEIDRKVLADLAVFD
                     KPAFAAIAEQARAKLAA"
     gene            complement(43957..44154)
                     /gene="rpmI"
                     /locus_tag="P5537_01360"
     CDS             complement(43957..44154)
                     /gene="rpmI"
                     /locus_tag="P5537_01360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006249241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HRV76719.1"
                     /translation="MPKMKTKSGAKKRFKVRSSGGIKRSQAFKRHILTKKTTKVKRHL
                     RGMTEVHAADEKLIRAMLPYA"
     gene            complement(44300..44821)
                     /gene="infC"
                     /locus_tag="P5537_01365"
     CDS             complement(44300..44821)
                     /gene="infC"
                     /locus_tag="P5537_01365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HRV76720.1"
                     /translation="MAQDKKQRVNREINAPELRLVGEEGEQLGIVSLNAALNMAEEAG
                     LDLVEIAPMAVPPVCKLMDFGKFKYQEQKKAHEARLKQKQVQVKEVKLRPGTDENDYQ
                     IKLRNLKRFLEEGDKCKVTLRFRGREMAHQEFGLRQLERVKADLEELGQVEQMPKMEG
                     RQMIMIIAPKKKH"
     gene            complement(44850..46769)
                     /gene="thrS"
                     /locus_tag="P5537_01370"
     CDS             complement(44850..46769)
                     /gene="thrS"
                     /locus_tag="P5537_01370"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004374367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HRV76721.1"
                     /translation="MPNITLPDGSVRSFDHAVTVAEVAASIGAGLAKAAIAGRTDGKL
                     VDLSHRFEADADLAIVTDKNAEGLEIIRHSTAHLLAHAVKELFPDAQVTIGPVIDNGF
                     YYDFSYKRPFTPEDLQAIEQRMGEIAKREIPVHREVWPRDKAVDFFKGIGEHYKAEII
                     ASIPAGEDVSLYRQGDFIDLCRGPHVPSTGKLKVFKLTKLAGAYWRGDSKNEMLQRVY
                     GTAWAKKDELDAYLHMIEEAEKRDHRKLGPQLDFFHLQDEAPGAVFWHPRGWRLFNTL
                     IGYMRERQEEAGYVEVNTPDVMDRGLWETSGHWQNYRQNMFTTVTEDERVFALKPMNC
                     PGAVSMFAQGLKSYRDLPLRMAEFGKVHRYEPSGALHGLLRVRHFTQDDAHIFCTEDQ
                     MEQECKDVVALILDIYKDFGFDNVRIKLSTRPENRIGSDETWDRLEGALAAALEHMGM
                     AYELFPGEGAFYGPKLEFVLRDTIGRDWQCGTLQVDMNLPERFDIHYVAEDNSRRRPV
                     MLHRALFGSLERFTGILIEHYAGAMPMWLAPQHAVVMNISEGQADYATEVAARLRKAG
                     FRVEADLRNEKINYKIREHSVQKLPYQIVIGDKEKAAGLVAVRARGGQDLGQMSLDSL
                     IERWRREVEAKAGTV"
     gene            complement(46955..47031)
                     /locus_tag="P5537_01375"
     tRNA            complement(46955..47031)
                     /locus_tag="P5537_01375"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(46995..46997),aa:Val,seq:gac)
     gene            complement(47110..47352)
                     /locus_tag="P5537_01380"
     CDS             complement(47110..47352)
                     /locus_tag="P5537_01380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HRV76722.1"
                     /translation="MGIIGTILIGLIVGFVARLLHPGKDGLGIIMTSLLGIAGSLVAT
                     YGGQALGIYHANEGAGFLGAVVGAVVILFVVTRLKK"
     gene            complement(47399..48190)
                     /locus_tag="P5537_01385"
     CDS             complement(47399..48190)
                     /locus_tag="P5537_01385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004374356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HRV76723.1"
                     /translation="MMPVLVFDIETIPDVAGIRAIENLPAGLSDFEVAEWAFQQRRAS
                     HGNDFLPHHLQRVVAISCVLRDAQHFRVFSLSEPESGEGEIIQRFFDGIERYTPQIVS
                     WNGGGFDLPVLHYRGMLHGVAAPRYWDQGEGDYHDSRDFKWNNYISRYHSRHLDLMDL
                     LALYQPRANAPLDDLAKLMGYPGKLGMDGSAVWQAWQEGRIAEIRDYCETDVVNTYLV
                     YLRFERMRGHLDAAAWAAEVETVREALGRIDAPHWKQFLAAWPQG"
     gene            complement(48187..48627)
                     /locus_tag="P5537_01390"
     CDS             complement(48187..48627)
                     /locus_tag="P5537_01390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1318 domain-containing protein"
                     /protein_id="HRV76724.1"
                     /translation="MKSPSMPSASLTGRVAAVFIGLALAFAVHAQGNLEIDTPAISAL
                     RKAMQQRHAQLAPLYASGAVGIAADGTVSLRDAAAVPLAQRAQANAAVAAENADRAAL
                     YREIARANGHPEWEGEVRRTFAQRWLDRAQPGWWVQQGASWSRK"
     gene            complement(48624..48836)
                     /locus_tag="P5537_01395"
     CDS             complement(48624..48836)
                     /locus_tag="P5537_01395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76725.1"
                     /translation="MYREDGMNPAARWLFAAALVASTAACVTINIYFPAAAAEKAADR
                     IIDEVWQLREGAGSAPVTPPAAGGTK"
     gene            complement(48843..50981)
                     /locus_tag="P5537_01400"
     CDS             complement(48843..50981)
                     /locus_tag="P5537_01400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76726.1"
                     /translation="METSAGGFELPCGGRSRRALACSLVLLMLVTAVPLAGAAVFRVL
                     AARVGEIAGPGFAVHELRVRLDAPAQGGEVDIGRLRIGAREWRALTLRCGRLRIDAGG
                     LACNAARMEQGGRRLPFEADVDLALGAGPVRIALRLPDGGRIEAGTEADGRLRARLHR
                     LTPAAAADLLEPWLGDLAAGLRGFKATGVLDAELDYRPADAGATTASLRGRLAGGGFG
                     RADGLLAAEGVGADFTLEARSTGAVWSWSAQLDWDAGAAYIHPLLVEAGPRLRARGRF
                     DGRRIELERAELALDGLAAASARGVIDTAAGTPDALSIELAGADLARIGPRWLAPLLA
                     PASAQRLRFEGRADARVELRAGRLETLAVELHGAGFGLAPPLGGGSARGDDGKEVVPV
                     EVLALGPVDGRVRWSSRGPGAAALQVGGGRWEKLALGAFALDAALEPAGLRLAGARIP
                     LLDGTLVLQDLALGWSAAGWEGSGGVVLEPVSMPLLSEALGLPLMAGVMSAALPGLQF
                     GPGELVLDGTLAVSVFGGWLQASGLRVREPFGVASHLTAEIEARHIDLAQLTETFSFG
                     SITGHIDADVRGLELSNWRPAAFDARIASIAGDERRRISQRAVENISALGGGGALAAV
                     QRSVLRLFETFGYRELGLRCRLANGVCEMGGLDAEPDGGVRADGGFTIVRGGGIPALD
                     VIGYNRRVDWNELVARLQRVVAEDVSPTID"
     gene            complement(51028..51918)
                     /gene="cysM"
                     /locus_tag="P5537_01405"
     CDS             complement(51028..51918)
                     /gene="cysM"
                     /locus_tag="P5537_01405"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase CysM"
                     /protein_id="HRV76727.1"
                     /translation="MEFRTLEDYVGRTPLVRLKRINAGRNNVILAKLEGNNPAGSVKD
                     RPALSMVMRAEARGRIKPGDTLIEATSGNTGIALAMAAAMRGYRMILVMPENQSVERR
                     QTMRAFGAELVLVPSSGGMEMARDIAEKMRDEGRGIILDQFANPDNPVAHYEGTGPEL
                     WEQTDGRITHFVSSMGTTGTIMGTSRFLKERNPDICIVGCEPEEGSSIPGIRKWPEAY
                     LPKIFERPRVDRFERVSQADAEEMTRRLAREEGIFAGISSGGAMHVALRIAAQVENAV
                     IVSIVCDRGDRYLSTGVFPA"
     gene            complement(51999..53174)
                     /gene="lapB"
                     /locus_tag="P5537_01410"
     CDS             complement(51999..53174)
                     /gene="lapB"
                     /locus_tag="P5537_01410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0008653 - lipopolysaccharide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapB"
                     /protein_id="HRV76728.1"
                     /translation="MEIEYWWLLALPLFFALGWLAARIDIRQVVQESRALPRSYLSGL
                     NFLLNEQPDKAIDAFVEAVRIDPQTVELHFALGSLFRRRGETDRAIRIHQLLVDREDI
                     SEDHRLQALGELGQDFLKAGLLDRAEAAFVRLRGTRANDVALRYLLEIYQQEKDWAKA
                     IEVAEALPGHEGVIWHTEVANFHCELAASALANSRHDDAQVHLDRAFEVNRRCVRASL
                     LLGDLLAAQGRDEEALEAWKRIENQDPNYLALVAERVMDACGRLGRVAQGHQLLRAWL
                     AAHASLDLLDELFHWELEREGPKAAYEMVREELRRNPTLLGLDKLLEAAALNAPAEQR
                     ADIDLIKQLIHGHTRRVARYRCNTCGFKARQFHWRCPACGGWETYPPRRTEEFDLTP"
     gene            complement(53181..53498)
                     /locus_tag="P5537_01415"
     CDS             complement(53181..53498)
                     /locus_tag="P5537_01415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004377174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LapA family protein"
                     /protein_id="HRV76729.1"
                     /translation="MPVMRAIIWIIRLLLFFLLFGFAIKNDHLVTLNFFFGIQWQLPL
                     VFVILVTFAAGALIGVTATLASMMRQRREISRLRRQLELVEREKASTETALAAAESRL
                     PMP"
     gene            complement(53575..53862)
                     /locus_tag="P5537_01420"
     CDS             complement(53575..53862)
                     /locus_tag="P5537_01420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit beta"
                     /protein_id="HRV76730.1"
                     /translation="MTKSELIAQLAERFPQLVAKDADYAVKMILDAMTDALARGDRIE
                     IRGFGSFALNYRPPRTGRNPKSGEKVLVPEKYVPHFKAGKELRERVDLGGS"
     gene            complement(53874..55577)
                     /gene="rpsA"
                     /locus_tag="P5537_01425"
     CDS             complement(53874..55577)
                     /gene="rpsA"
                     /locus_tag="P5537_01425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004377177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HRV76731.1"
                     /translation="MSNATPAFEESFAALFEESLALQEMRAGEVITAEVVRIDQNFVV
                     VNAGLKSESYVPIEEFRNDRGELEANIGDFVHVAIDALEDGYGETRLSRDKAKRIAAW
                     NDLEKALNDGTLVKGVITGRVKGGLTVMTNSIRAFLPGSLVDMRPVKDTTPYEGKEYE
                     FKVIKLDRKRNNVVVSRRAVLEESMGEEREKLLANLKEGTVIKGVVKNITDYGAFVDL
                     GGIDGLLHITDLAWRRVRHPSEVLSVGDEIEAKVLKFDQEKNRVSLGLKQLGEDPWVG
                     ISRRYPQGTRLFGKVTNITDYGAFVEVEQGIEGLVHVSEMDWTNKNIHPTKVVQLGDE
                     VEVMILEIDEDRRRISLGMKQCMSNPWDDFAINHKKGDKVRGQIKSITDFGVFIGLEG
                     GIDGLVHLSDLSWSESGEDAVRRFKKGDEVEAVVLAIDVERERISLGIKQLEGDPYTN
                     FIATHEKNSLVRGTVKSVEPRGAVISLGDDVEGYLRASEAAPHRVDDLTTMLKEGDSV
                     EALVINVDRKTRSISLSIRAKDQAEQSEAMNKLASESSASAGTTNLGALLKAKLNEQK
                     Q"
     gene            complement(55668..57629)
                     /locus_tag="P5537_01430"
     CDS             complement(55668..57629)
                     /locus_tag="P5537_01430"
                     /EC_number="2.5.1.19"
                     /EC_number="2.7.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-phosphoshikimate
                     1-carboxyvinyltransferase/cytidylate kinase"
                     /protein_id="HRV76732.1"
                     /translation="MEFLDLPPMLGAAGSVRLPGSKSISNRVLLLAALAEGETDIRDL
                     LLSDDVERMLEALRALGVDWRREGDSLDYRVRGVGGPFPVKAAELFLGNAGTAFRPLT
                     AALALSGGEYRLSGVPRMHERPIGDLVDALRQLGADIACTANEGYPPLHLKPATIRPG
                     GVVRVRGDVSSQFLTALLMALPLTGVETTIEVVGELISKPYIRITLELMARFGVQVNQ
                     QGWERFVVPGGARYRSPGTVFVEGDASSASYFLAAGAIGGGPVRVEGVGRSSIQGDVR
                     FAEALEQLGARITLGDNWIEAAAPAGGVLKAFDLDLNHIPDAAMTLAVAALFADGPCR
                     LRNIASWRVKETDRIAAMATELRKLGAEVEEGADYLVVQRPQRLQPAAIDTYDDHRMA
                     MCFSLASLGGCRVRINDPKCVNKTFPGYFEAFARVAQPVPVLAIDGPSASGKGTVAAR
                     VAEALGWHYLDSGSLYRLVALAAMRAGVAFDDEAGVAALAATLPARFEGGRVLLGEGA
                     DCDVTDEIRSEACSVGASKVAVLAAVRAALLDRQRDYRAAPGLVAEGRDMGSVIFPDA
                     GLKVFLTASAEARAERRYKQLIEKGLAANMESLLKDLQERDARDAARPVAPLVKLPDA
                     ALLDTTQRNVDEAVAFVLDLVGQGAKSPG"
     gene            complement(57681..58568)
                     /locus_tag="P5537_01435"
     CDS             complement(57681..58568)
                     /locus_tag="P5537_01435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004665 - prephenate dehydrogenase (NADP+)
                     activity [Evidence IEA];
                     GO_function: GO:0008977 - prephenate dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_process: GO:0006571 - tyrosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase/arogenate dehydrogenase
                     family protein"
                     /protein_id="HRV76733.1"
                     /translation="MAHIGKLVVCGVGLIGGSFALALRRAGAVERIVGIGRRREVLER
                     ACALGVIDEIAEGWADALDGADLVLLAAPVGQMDAILAAMAPHLRPGTVVTDAGSTKR
                     DVVAALRSHLGAALADVVPAHPIAGAEKSGVEAAFAELYMGRKVVLTPLPESRPEAVQ
                     KVRDAWEACGANVVGMTPQEHDRVFAAVSHLPHLLAFGLVDDLAGRSNAPLLFSHAAS
                     GFRDFTRIAGSHPEMWRDICVANRVALLEELDAYLGELARLRMMLVEGDGDGLEAVFE
                     RARRARNAWAEGLPIRTAE"
     gene            complement(58583..59680)
                     /gene="hisC"
                     /locus_tag="P5537_01440"
     CDS             complement(58583..59680)
                     /gene="hisC"
                     /locus_tag="P5537_01440"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HRV76734.1"
                     /translation="MSIASLAPDYIRAIMAYQPGKPISELAREMGIAEESIVKLASNE
                     NPLGMSVRARDAAITAIGEISRYPDGGAFALKKALCARFGVEPAQLVIGNGSNDILEL
                     ASQAFLAPGLSAVYSRHAFAVYPLATNARGARGIEVAAKNFGHDLDAMAAAIEPQTRV
                     VFIANPNNPTGTFVPGAELEAFLAEVPRHVLVVLDEAYTEYLAPEQRYDSIAWLARFP
                     NLLVSRTFSKAYGLAGLRVGYAIAHPEVADLMNRVRQPFNVSSVALAAAEAALDDDEF
                     LARSAEVNRRGMAQLVAAFRELGLEWIPSAGNFVTFKVGDAIGVNQALLRQGVIVRPI
                     AAYGMPHWLRVSIGLPEENARFIEALRQALA"
     gene            complement(59743..60810)
                     /gene="pheA"
                     /locus_tag="P5537_01445"
     CDS             complement(59743..60810)
                     /gene="pheA"
                     /locus_tag="P5537_01445"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HRV76735.1"
                     /translation="MSDELLKLRNEIDRIDEEILARLAERARCAQRVGEIKRGVMYYR
                     PEREAQVLRRLAELNPGPLSADAVKTIFREVMSACLGLEQPLRVAYLGPAGTFSESAS
                     RKHFGSAPNFMAMAAIDDVFRAVEAGNADYGVVPVENSTEGAVGGTLDLLLANPLKVC
                     GEVRLRIHQQLMSRAEGIGAAKRVYSHAQSLAQCHEWLNRNLPHLPRIPVASNAEAAR
                     MASEDPESCAIAGDAAAQLYGLNILAPNIEDDPNNTTRFLVIADHDAGPSGKDRTSLV
                     FSAPNRPGAIHSLLEPMARHGVDMTKLQSRPARSGLWEYVFYADINGHRDDPEVAAAL
                     RELDERAAFVKIIGSYPVAAI"
     gene            complement(60890..61987)
                     /gene="serC"
                     /locus_tag="P5537_01450"
     CDS             complement(60890..61987)
                     /gene="serC"
                     /locus_tag="P5537_01450"
                     /EC_number="2.6.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0004648 -
                     O-phospho-L-serine:2-oxoglutarate aminotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006564 - L-serine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoserine/phosphohydroxythreonine
                     transaminase"
                     /protein_id="HRV76736.1"
                     /translation="MSRVWNFSAGPAALPEEVLRQAADEMLDWHGSGMGVMEMSHRGK
                     EFTAIAAQAEADLRELLAVPANYRILFMQGGAIAENAIIPMNLMGDRRVADYVVTGSW
                     SQKSQKEARKYAEVNIAASSEAGGFKTVPAMAEWKLSADPAYVFTCTNETIGGLEYPF
                     EPDLAQIGRAEVPVVADMSSHILSRAIDVSKYGLIFGGAQKNIGPAGLTIVIVREDLL
                     GHAMPHCPTAFDFRTVADNGSMYNTPPTYGIYIAGLVFQWLKRQGGVAAIEAQNVAKA
                     KLLYDFLDASDFYENRIEPACRSRMNVPFFLKDEALNDAFLAESKAAGLVQLKGHKSV
                     GGMRASIYNAMPLAGVQALVDFLRDFAARRG"
     gene            complement(61987..>64475)
                     /gene="gyrA"
                     /locus_tag="P5537_01455"
     CDS             complement(61987..>64475)
                     /gene="gyrA"
                     /locus_tag="P5537_01455"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HRV76737.1"
                     /translation="WNRAYKKSARIVGDVIGKYHPHGDTAVYDTIVRMAQDFSLRYML
                     VDGQGNFGSVDGDNAAAMRYTEIRMARIGHELLADIDKETVDFGPNYDGSEKEPLVLP
                     ARIPNLLINGSAGIAVGMATNIPPHNLGEIVDACLKLLAEPDTDIEALIDIVQAPDFP
                     TAGLIYGLAGVREGYRTGRGRVIMRARTHFEPIGKTDRQAIVVDELPYQVNKRTLQER
                     MAELVNEKKIEGISEIRDESDKSGMRLVIELKRGEMPEVVLNKLFKHTQLQDSFGMNM
                     VALVDGKPRLLNLKQMLVCFLEHRREVVTRRTIFELKKARDRGHVLEGLAVALSNVDE
                     IIALIKAAPTPADAKRELMAREWRSALVEEMLSRAMADSYRPEGLDAQYGLSAQGYRL
                     SETQAQAILELRLQRLTGLEQDKIVGEYREVMDLITDLLDILARPERITAIIVEELGA
                     IRNQFGDPRRSELVMNTAEINIEDLITPEDMVVTLSHTGYFKRQPLADYRAQRRGGRG
                     KQATSMKDEDFIDHLFVANTHDTVLCFSSRGRCYWLKVYEVPEGTRNSRGKPIVNLFP
                     LVEGEKITAVLPIKEFDEEHFVFMATSEGTVKKTALSAFSNPRKAGIIAVNLDDGDHL
                     IGVAITDGQCDVMLFSDAGKAVRFAETDVRPMGRDARGVRGMTLEDGQAVIAMLVAKD
                     ESQSVLTATENGYGKRTPVAEYTRHGRGTKGMIAIQTSDRNGKLVGAVLVEPGDEVML
                     ISTGGVLIRTSVESIREMGRSTQGVTLINLDEGTFLASIEKVAESESDESMRANGEGA
                     AGGEEAAGDAGEAPAAGEGEAPAAGEEGEA"
BASE COUNT         9956 a        22922 c        21643 g         9854 t
ORIGIN      
        1 gcgatcagta gatcggctcg accagcaggc ggtcgtccac gtagctctgc aaaaggttgt
       61 tgatcgcgaa cagcgtcccg gtcgacgacg aagggcagcc gccgcacgcc cccttgtagc
      121 gcaccgtcag ggtgaattcc ttcagcttca cgacgtcgag gccgccgccg tcctggtcga
      181 ggaaggggcg gatgtgctcg tcgaggatct ggttgatgcg catcagcaac tccgcatcgt
      241 cggcctccac ctccaccgcc tcctcgcccg cggcctcgtc accgccgctc gccgtgccgg
      301 gagcccctcc cggcccggcc gggttggcga tgccgatgac gcggcgcgcc ttgtgccctt
      361 cgatcagctc ggtgacggca ggctcgatcg ccgaccaggg cgtgcccggg tcgcgggtga
      421 tcgtgatgaa gcccccggtg cagtagatgt cgaccacgcc gggcaccgcc agcaggctct
      481 cgccgagggt gtcgccgacg acgggaacac cgacgcggaa gtgacgcggc gcaccggtgt
      541 agagcggcgc gtcgagcatg aacttgttcg ccagggggtt gggcgtggac atgacggcgg
      601 tgacgttggg catggcgggc tcctgcggct cgggtggggc gttgctgcga cgttcggaaa
      661 cgttccgcgc agtccgtgca cggaggcatc ggggtgctgc ggagcgcaga tcggattgcg
      721 acgctacgaa gcgaatacta cttgtcgtta acgtcaacgt caattaacat gaactcgcac
      781 gctccccgaa ccgatcgcag gaaccggaac ccgacatgaa ggaatatctg ctgcttttgc
      841 tcggcacggc cctggtgaac aacgtcatcc tggtccgctt cctcggcctg tgccccttcc
      901 tcggggtatc gggcaagctc gagaccgcgc tcggcatggg cctggccacg accttcgtgc
      961 tcacgctgac ctcgggcgcg acctgggtgg tcgagcacgc cctgctgcag ccgctggaca
     1021 tgatgcacct gcgcatcctg acctacatcc tggtgatcgc cgcggtcgtg cagttcaccg
     1081 agatggcgat ccagaaggcg agcccggtac tgcaccacac cctgggcatc tacctgccgc
     1141 tgatcaccac caactgcgcg gtgctcggca ccgcgctgct caacctgcag caggacaaca
     1201 gcctgatcca gagcctgctc tacggcgccg gctcggcgct cggcttcacc ctggtgatcc
     1261 tgctcttcgc cggcctgcgc gagcgcatcg cgctcgccaa cgttcccgcc gccttcgccg
     1321 ggacgccgat cgcgctgatc accgccggcc tgctgtcgct ggccttcatg ggcttcgccg
     1381 gcctgccggt gcgctgaaac cttcctctcc tccggacacg caaggagtac gacgatgacg
     1441 atgatcctct ccgtagcggt ggtcgccgcc ctgggcctgg gcctgggctg gctgctcggt
     1501 ctcgcctcgc agtggctggg cgccaccacc gacccggtgg tggagcgcct caccgaggcc
     1561 ctccccggct cgcagtgtgg ccagtgcggc tacccgggct gcggccaggc ggcgatcgcg
     1621 ctgtccaagg gcgaggcgcc ggtcaccctg tgcccgccag gcggccgcgt cgtcgcagag
     1681 aagctcgccg agatcctcgg caccaccttc gacccgggca acctgcccga ccgcggccca
     1741 ctgctggcgc gcgtgcgcac cgactactgc atcggctgct cgcgctgcat caagtcctgc
     1801 ccgaccgacg ccatcctggg cgcgaccaag cagctccacg tggtgctcga ggaggcctgc
     1861 atcggctgcg gcgcctgcgc cgaggtctgc cccaccggcg gcatcgacct cgagggcatc
     1921 ccggtcaccc tgcgcaactg gcgctggcac aagccgggcg tgggacacgc ctgagcgccc
     1981 acgccaagca caccggaacc ccacacgcca tgaagatctt ccgcttccgc ggcggcatcc
     2041 accccgaagg caacaaggat cccaccgcct gccacccgat cgcccgcctg ccgctgccca
     2101 agcgcctgta catcccgctg cagcagcaca tcggcgagcc ggccgcaccc gaggtcaagg
     2161 tcggcgacca tgtcctcaag ggccagcgcc tcgcccgcca ccagggctcg gtgtcggcgc
     2221 cggtgcacgc gcccacctcg ggcacggtga tcgcgatcgg cgaccacatg gcgccccacc
     2281 cttccggcct gccggtgcag acgatcacgc tcgagcccga cggcgaggag cgctgggtgg
     2341 agaccgagcc ggcggtcgat cccttctcgc tcacccgtgc cgaggtcgcc gcgcgcgtac
     2401 gcgacgccgg catcgtgggc ctgggcggcg cggccttccc ggcggcggtc aagctcgacg
     2461 ccggcaaccg ccacccgatc gacacgctga tcatcaacgg cggcgaatgc gagccctacc
     2521 tgacctgcga cgaccgcctg atgcgcgaag gcgcgggcta cgtggtcgag ggcgtgcgcc
     2581 tgatcgccaa cggcctcggg gcgaagcgca ccgtgatcgc gatcgaggac aacaagcccg
     2641 aggcgctcga ggcgatgcgc gtcgccgccg ccgctcaccc cggcatcagc gtgctgcgcg
     2701 tgccttcgcg ctacccgatg ggctccgaga agcaactcgt caccaccgtg accgggcgcg
     2761 agatccccgc cggcaagctg tcggccgaga tcggcgtcag cgtgcacaac gtcggcaccg
     2821 cgcttgcggt gtgccgcgcg gtgcgcttcg gcaagccgct ggtgtcgcgc gtggtcaccg
     2881 tgggcggcgg cgcgatccgc aacccgcgca acgtggtggt gccgatcggc acgccggcgg
     2941 ccgacctggt cgagttctgc ggcggcttca ccgtgacgcc gacccgcgtg ctgatgggcg
     3001 ggccgatgat ggggcaggtc ctgcccggac tggaggcgcc ggtggtcaag ggcaccagcg
     3061 gcatcatcgc gctcaccgcc gccgaggccc acgcggcgag cgagcgcgcc tgcctgcact
     3121 gcgggcgctg cgtcgatgtc tgtccggtcg gcctggtgcc gctcgaactc gccgcgcgcg
     3181 tgcgcgccgg gcgcatcgac gacgccgccg agctcggcat gggcgactgc ctgtcctgcg
     3241 gctgctgtgc ctacgtgtgc ccggcgcacc tgccgctggc ccacctgttc aactacgcca
     3301 agggcgagat cgccgcgcgc cgcgaggccc aacgcaaggc cgaggagacg cgcaagctgg
     3361 ccgaggcgcg ccggctgcgg ctggccgcgg aagccgcggc caaggctgcg cgccgccccg
     3421 cccgcacgac cgagaaggca gagaccgaat catgacgacg tggaccccga accgctcccc
     3481 ggtggccgca ccccacgtgc atgggcgcgc caacgtcccc caggtcatgc gcacggtcct
     3541 gctcgccctg ctgccggcga ccgcgaccgg cgtctggctg ttcggctggc cggcgctcaa
     3601 tacggtgctg ctggcgatcg ccggctgcgt ggccgccgag gccgccgcgc tggcgatcgg
     3661 gcgcaggccg gtaggccata cgctcgccga cggctcggcg gtggtcaccg ggctcatcct
     3721 cgcgctctgc ctgccgccgt gggcgccgtg gtggctggcg ctgctcggcg gtgtctttgc
     3781 gatcgtggtc ggcaagcagg tcttcggcgg cctgggccag aacgtgctca acccggcgat
     3841 gctggcgcgg gtcgccctgc tggtgtcctt cccgctcgag atgaccgcct gggtggcgcc
     3901 gcagccgctg ttctcggccg cttcccctgg cctcgtggaa ggcctcgcga tcaccttcgg
     3961 cggcggtccc ctgccggacg cggtgagctc ggcgaccgcg ctcgccccgc tcaagctcgg
     4021 cggcgacttc gccgccggcg aggcgctgct cgcgctcgcg ctcggcacgg tgccgggcag
     4081 cttgggcgag acctccgcgc tcgcgctcct cgccggcggc gcgctgctgg tcgcccgccg
     4141 catcgtgccc tggcagatcc ccgccgccct gctcggcacc ctcgccgtgc tcgccgcgct
     4201 gttcaaccag atcgaccccg cgcactaccc ggggccgctg ctccacctgc tcggcggcag
     4261 cgcgatgatg tgcgccttct tcatcgccac cgacccggtg ggcgcgccgg tcaccccgct
     4321 cggacgcgcg atcttcggcg ccggcatcgg cgcgctgatc tatgtgatcc gcacctgggg
     4381 cggctacccc gagggcgtgg ccttcgccgt gctgctgatg aacgcggcga cgccgctgat
     4441 cgatcgcctc gtgcgtccgc gccgttatgg ccgcctgcgt acgggcgccc ccctccccct
     4501 ggccccgaag gaggacggcc gatgagctcg acccttgccg ccggcctgcg ccggcgcccc
     4561 gggctgctgc tgggagcctt cgccctcggc tgcagcgcga tgctcggcgc cggcgacctc
     4621 gccacccgcg aggagatccg ccagcgccag gccgatgacc tgcgccacgc cctcgaccag
     4681 accctctccg ccgtgcccca cgacaacaat ccggccgagg acacgatcgc ggtcgaggac
     4741 gcgggccgca gcgtcacggt gtatcgcgca cgcatggcgg ccgaggtcaa cggcgtcgcc
     4801 ttcaactggg tgagcgaggc cggctacggc gggccgatca cgctcaccgt cggcatcggt
     4861 cgcgacgggc gcatcgccag cgtgcgcgtg ctctcgcaca gcgagacgcc gggcctgggc
     4921 gacaagatcg acgtgcgcaa gtccgactgg atccgcggct tcgacggccg cgggctcgac
     4981 accggcacgc gctggggggt gcgcaaggac ggcggcgagt tcgaccagtt cgccggcgcc
     5041 accatcaccc cgcgcgcggt ggtgggggcg gtccacgcca gcctgaagtt cttcgccgcg
     5101 caccgcgagc acctgctcgc cgcgccggcc ggcgccgcag ccgcggcggc acaaccgggg
     5161 agcccgacat gagcgaggtg cgcagggtcg tccgcgacgg cctgtgggac aacaacgtgg
     5221 tcttcgcgca gatgctgggc atgtgcccga ccctggccac caccggcagc gcgaccaacg
     5281 ggctcggcat gggcctggcc accacggtcg tgctggtgtg ctcgggcgtg ctggtctcgc
     5341 tgtttcgcaa cgtgatcgcg cgcgaggtgc ggatcgcgat ctacgtgctg ctgatgtcca
     5401 ccgtggtgac cctggtcgac atgacgatga acgcctggct gcacgagctg cacaaggtgc
     5461 tcggcctgtt catcccgctg atcgtggtca attgcgccat catgggtcgc gccgagtcct
     5521 tcgcgtccaa gcgcgccccg ggcatggcgg ccctcgacgg cctgatgatg ggggtgggct
     5581 tcaccctcgc cctgatggtg ctgggcggcg tgcgcgaggc gatcggccag ggcacgctgt
     5641 tcgccgacgc ctcgatgctg ctcggagagc acttcgcctt cctcgagctg cggctcgacg
     5701 gctaccgcgg cgtgctgctg atgatcctgc cgccgggcgg cttcctcgcc ctcggcttcc
     5761 tcgtcgctgc ccgccagcgc atgctcgccc gcgcccgggc gcgcagcgag ggcgcgggcg
     5821 ccgcgatgac ggcgggcacc tgagccgggc ggaatcgccg aagcccatgc atggacagcc
     5881 agggagagag gacgaatgaa gatcagtgtc agctacgcgc atcccgagaa gccggcgtgg
     5941 gtgcgcctcg acgtcgaaga aggctgcacg ctgcgcgcgg cgatcgagcg ctcggggatc
     6001 ctcgggcgct acgaggacat cgacctgacg cgcaacaagg tgggggtctt cggcaagatc
     6061 aagccgctcg acactgtgct cgccgaaggc gaccgggtgg agatctacca gccgatcgtg
     6121 atcgatccga agaccgcgcc gcgccgcaag cgcgccgaag cgggggacgg agacggagcg
     6181 gaagagggct gaactcggcg cgcccgcggc agaggggctt ccgccaggga ggccgtccct
     6241 tgccccggct gcgcccgctc aggcgctcgg actcatcgcc gggatcggct cgagcgcgcg
     6301 cgcggcgatc gagcgccgcg cctccttctc ggccgcgtcg atctcgtcga ggatggcgcg
     6361 gatgtcttcc atctggcgct cgagcatcgc cctgcgcgca cccagcagtt ccatgaagtg
     6421 cgacatctgt gcctgctcgc ccggtgcgtt gtcatagaga tcgaagagct cgcgcgtctc
     6481 ctgcagcgag aaacccagcc gcttgccgcg caggatcagg ctcagccgca cgcggtcgcg
     6541 gcggctgtag atgcgccggc tgccgcgacg ggccgggctg atcaggccct ggtcctcgta
     6601 atagcggatc gcccgggtcg tgatgtcgaa ttccttggcg agatcggata tcgtatacgt
     6661 cgtcgcattc gccgattcgc gcatccgcac tgcctttccg gcgatttctt cgttcatttc
     6721 attctccgtg tcgcgatgcc cgctcctgca tcgctctcgc ctcgcgccgc tcgcacgacg
     6781 cgacgtacgc atgccacgca tgcaatccat cccgagacga cacggatgat tgcacagaag
     6841 ctccgctaac gtaaacgtca acaagcgaca cgccgatgcg cgggctcgga tacgcgcgcg
     6901 ccgggcatca cgagcgctcg cacacacctc gcggcagcgc ggcctccgat cctcccgccg
     6961 gtgcctgcac cgcctccgtc gcaaggcccg cgatgccgcg cacgaagacc cgcgccacca
     7021 ctcttgccag ggcctcgtag gacagcgtcc cctcggggcg cagccaggtg aaggtccagt
     7081 tcatcatccc gaacaacacc atcgcgaccg ccttgtcgag ggccacgccg cgcaggccgg
     7141 gctcgaccgc ctcgatcgtg agcgcgaagg cgcgcaccac ccggcgctcc tgctcgtgga
     7201 tgcgcgcacg ctgctcggga ctgaggaact tgacgtcctg gatgagcacg acgtgctgcc
     7261 gtcgcccgcc ctcgtaggcc tgcatgaagc gcaggatcag gcgttccagg cgctcacgcg
     7321 gcgccgccgc cgcggcctcg acctccgcca cgatcgcaag cagttcctcg acgtggcctg
     7381 cggcgatgtc gtagaggatg tgttccttgt cgcggtagta gtggtacagc agcgccttgg
     7441 aaacgccgca ttcgcgcgcg atctccgcca tcgacgcgtg gtggaagccc cgcgccgcga
     7501 aaagccctgc ggcagcatcg aggatcgtcg cgcgctgcac ctggaaggtc ggggccttgc
     7561 ctctggccat cgggtagttc gtcctttgct gcggccgctc cgtggtgctc gagcgcacac
     7621 atgcgggccg gtttttccgc tcgatcgccg gcagccggat tgtgcccggc aacaagtccg
     7681 accgatcagt cgatcaatag cgatcttgcg ccatatcaag acaaaagcga tctttttgca
     7741 accccgcttg cgtgccgtgc cctccccggt cgccgcatgg cgcagccgag acctgccctc
     7801 gacctgcatg ctgcccgtcg acgcgaacgt ccacgcccgt cgcgcacggg catgatactg
     7861 tcctcgcggc acgcctctca tccaaccgga gccaatccat gccctgctac gaaatcgacg
     7921 gcgtccgccc ggtcgtccat cccaccgcct atgtccaccc cgatgccgtg ctgatcggcg
     7981 acgtgttcgt cggcgccggc tgctacgtcg ccccgctcgc ctcgctgcgc ggcgacttcg
     8041 gccgcatcgt gctcgaggag ggcagcaacg tgcaggactg ctgcgtgctg cacagctttc
     8101 cgggcatcga taccgtggtc gaggccaacg gccacgtcgg ccacgccgcg gtgctgcacg
     8161 cctgccgggt cggccgcaac gcgctcatcg gcatgaatgc ggtggtgatg gaccacgcgg
     8221 aggtgggcga aggcagcatt gttgcggcgg ccgccttcgt gaaggcggaa atgaagatcc
     8281 cacccggcgt gctcgtcgcg ggcgtacccg ccaaggtcct gcgcgaactc accgaacagg
     8341 agcgcaaatg gaaggtgatc ggcaccgagt gctaccagaa cctcgcccgc cgcagcctcg
     8401 ccaccctcaa gccctgcgac ccgctgcgcg aaggcgaccg cgagcgcccg cgcttcgagg
     8461 cccccgacgt catgccgctg agcgacgcgc gccggcgcac cgactgaaca ctcgcccggc
     8521 cccgaaccgc cgtcagagcc gcctgcaaac cttccccctg ctcccctgcg ccgccctccc
     8581 cgggcagttc aggcgaaggg atacggccac tcgtcctgct cctccgagaa caggcccgcg
     8641 accagcgtgc gcagccagcg gttgcgcgga tcgtggtgga agccccggtg ccagtgctgg
     8701 aagagctcga tgcgcgggat cgccagcggg ggctcggcca tgcgcacccg ctcgcccacg
     8761 cgcgtgaagt actggccgat cgcatgcggc agggtcacca ccaggtccga gcgcccgatg
     8821 atgccgggca ggctcatgaa gtggggagtt cgcagcacga tgcggcgctg gatgcgcagg
     8881 cgctcgaggt atttctcgaa gatctcctgg ctgcgcccct tggcgcgcac cgcggcgtgc
     8941 tcgagcgaca ggaagcactc gagggagagc tggtgatcct gcaccgggtg atcggcgcgc
     9001 aacaggcaca cgaagcgatg gctgagcagc ttctcgcggt agaagccggc cgcatccagg
     9061 tcggggtgat agccgatcgc cagatcgacc tcgccatcct ccatcgcgcg catcagttcc
     9121 cccggcgcga gcgtcaccga atcaagcatg gccagcggcg cgatccggcg cacgctgtcg
     9181 aggatgcgcg gcaggaagac catctcgccc acgtcggaga gcgcgacggt gaggttgccc
     9241 tcgtacctcg ccggatcgaa gcggtcggcg acgaagaaat ccgcctccag ccgggcgagc
     9301 atcgcccgcg cgctgctcgc cagcgcatgc gtgcgcgcgg tgggcgtgac gcccgacgcg
     9361 gtcttgatga acagcggctc gccgagcgca cgacgcaggc gaccgagcgc gctgctcacc
     9421 gtcggctggc tcagtccaag ggcctgcgcc gcgcggctca cgctgccggc ctcgtacacc
     9481 gcgagcagga tccgcagcag gttcaggtcg aagtcacgca ggctcatgca ggtcgagggt
     9541 tattgatagc gtcgataaag gtaatccgtt catttgtatt gtgcagcatc gccgcgagga
     9601 atttaatgaa cccaacaaaa caataaattc cgccccttaa ggggaatccg gtcgaggaga
     9661 caccacgatg atgttcgtca tccccctggc gggccggcag cccgctcccg cgccccgcgc
     9721 gaacaactgc ggagcggcat catgaacgcc gccgaatggc tgctcggcgg cgagcccgcg
     9781 cggatcgcgc tgatcgaggg cgatgtccgc atcgactacg ccggcctgcg tgccgacgcc
     9841 atgcgcagcg ccgcggccct gctcgacgcc ggcctgcgcc cgggcgacgc ctgcgtgctc
     9901 gccctgcccg acggcatcga atgggccacc gccttcatcg gcatgctgtg ggcgggggtg
     9961 cgaccgatcg cgatcaaccc gcgcacggca tccgagcaga tcgccgacct gatgctggac
    10021 tcgggcgccg ccgcggcgct gctcgaggac ggggccgcgc gtgcattggg cgacaagcgc
    10081 gcgatcgctc tcggcgagtg gcgccgcagg gtggagcgtg cgaccgcgac gcccgcggcc
    10141 gcgccggcag ccgacgacga cccggccttc ctgctctact cgtccggaac caccggccgc
    10201 ccgaagggca tcctgcatgc ccaccgggcg atccgcgacg cccatgtgtt tgcccgcgac
    10261 attctcggcg cacgccccga gcaccgcttc tactccagct ccaagctgtt cttcgcctac
    10321 ccgctcgcca acgccttctt cgccggactg cgcctgggcg ccaccgtcgt gctcgacccc
    10381 gaatggcccg acccggcgcg cgtcgcggcg atggtcgagc gccaccagcc gcacatcttc
    10441 ttcagcgtgc ccaccctcta ccgccgcctg gtcgacgccg gcgtgcgttt ccgcggcctg
    10501 cacgccgcgg tctccgccgg cgaggcctgt ccgcccgcgc tcgcacgcga atggcaggcg
    10561 atgaccgggg tgccgctggt caatggctac ggcaccaccg agacgctgtc gctggtgctc
    10621 taccgtacgc cggagatgga gtccgcgcac cccacgccgc tcaccaccat ccaccccgag
    10681 cagctcacca gcggcgaggt ggaaacctgg cggctgtggt tcgctcaccc cgcggtcgcg
    10741 ctcggctatt cgcgtgtcgt cacccacgac agcgcacgct ttgccgacgg ccacttcgcc
    10801 cccggcgacg tcttccgccg tgcgcccgac ggcgaaggct ggctgttcgc cggccgcagc
    10861 gaccagctcg tcaaggtgtt cggccgctgg gtggacgtgg tcgcggtcga gcaggccgtg
    10921 caggaacgca tgcgcggcaa ggccgaggag gtgtgcgtga tcccggcgca gggcgaggac
    10981 gcggacatga tccgcctgca cctcttcgcc attcccggcg acctgccgcc accacaggtg
    11041 ctggccgccg cccaggcagc catcgagagc ctgccgcctt accagcgccc cgagaaaatc
    11101 cacctcgtgg accatttccc gcgcaccgac accggaaagc tgcgccgcaa cgaactcgcg
    11161 cgccacaccg gctgacgcgt tgcagtcccg agcgcagccc cgggcccgtc acgcaccggg
    11221 gccgctcgcc gcgctgtcga gtgcgcgctc gacgctggcg atcttgtccg ccatggtctg
    11281 ctcgcggtca gtgcgcgtac ccagccgcat cgagctcgtg atccgcggcg ctcccatcgc
    11341 atgcacgacc tcgtggcagc gcttgaccgc ggccatcacc tcgtcccact cgccctcgat
    11401 gttggtgccg taggcgtgga gctgcgactt caggccggcc tcgcggatca cccgctcgca
    11461 ggccgccacg tgggctgaaa cggacaggcc cacgccgagc gggaccacgc acagatcgac
    11521 aatgactttc acggacgcct cctgcagcgc tcttcgggac gcccgattct agcgtcgcag
    11581 gcgatttccg cgtaccgcgg ccgtaccgcc gccggccagc accacgccga cctcctcgcg
    11641 cgcgacctcg cgccactcgc ccacccccag cccgtccagg caccacggcc cgatcgccac
    11701 ccgcaccagc cgcagcgtgg gatggccgac cttcgccgtc atccggcgca cctgccggtt
    11761 cttgccctcg cgcagcacga tctccaccca gctcgtcggc accgacttgc gaaagcgcac
    11821 cggcgggtcc cgtggccaca gccagtcggg ctccggaatg cggcgtgctg cacatggctg
    11881 cgtacgaaag tcgcccaggt ccagccccgc acgcaggagc acgagcgcaa cttcgtcgat
    11941 ctccccgtcc acctgcacca gatagcgctt ggccagcttg tggcgcggat cggcgatgcg
    12001 gtgctgcaag gctccgtcgc ccgtgagcag caccaacccc tcgctatccg cgtccaggcg
    12061 tccggcggga tagatgccag gcaccgcaac gtagtccttc aaggtcctgc ggccggcctc
    12121 gtcggtgaac tggcacagca cgccgaaggg cttgttgagg agcagcaggc gcgtatccgc
    12181 cagccctcca gcccggatgt cggaattttt tacacttgaa ccagacctgc gggagcgttc
    12241 gaaagatggc aagcccatga aataactgtc tttccttgtt ttggttgttt ttcgcgaatg
    12301 tcgacaaaac ttacataagc atgaatttac atttctccaa atttaacttt tccaggcaaa
    12361 tcctgatgcc tgagaaatgg cacgctattt gcaggcgcag gacagctccc atccgggagc
    12421 atcgtaccca ttccgcaacc cgatcgagga gttcgccatg cgcaccctgc tttccatcgc
    12481 cgtgctctct gccctttctg caccggcctt tgcctttccc aactcgcagc cgcttcccga
    12541 acccgagacg ctcgccctga tcgcggtcgg cctcgtcggc gtactcgcca gccgcctgcg
    12601 caacaagaag taaggcccga gtaccacacg cagcgggggc ccatatcccc gtgcaatccg
    12661 tccaggcctg caagcaaggg cccggacggc tcagaatccc agggagtcca tcatcatgtc
    12721 cacctcgcgc atcctcagca tcaaggtcac ctatcccgac cagttcctcg aaccgagcac
    12781 tttcgacctc cagttcctcg gagcatcgga tttcgggtca ggctattacg atgcttggtg
    12841 cgcggatgcc gacatccctc tcgatgtggt cggccccgtc aatggcgtct actcgctcac
    12901 actcaaggcg ggactctatt ccagctacga ttacggcgcg atccccgctg ccttccagtc
    12961 aatcgagctt cctggtcacc tcgatgaagc caactggctg ctgaaccagc acttcacggt
    13021 cggtgcgagc ccctacacga ccaacgaagt acaggccgcg ctgtggaccc tgctcggcga
    13081 ccaggaccgg gtggccaccc tgctgccagg gaccgacgcg acgcgcgtcc agacgctggt
    13141 ggatctggcc ctgcagaacg acggcttcgc gccggacatc accgacgaca acccgaacaa
    13201 cgacgagatc ggcctgctgc tggacctgtg gaaggacagc aataacaacg gcgtgcgcga
    13261 tgcgaatgag gtcgtccagc aaccgctcat cgtgatggtc aagtccgccg cgctgggcga
    13321 ccgcgtgtgg cacgacgtga acgccgacgg catccagaac gtgggaggcg acggcgccta
    13381 caccgagcag ggcatcgccg gcgccgtcgt gcgcctcgtg cacgatcgcg acggcgacgg
    13441 cgccttcacc agcgcgggcg aggtcctcgc caccacgacc accgacgcgg acggcaacta
    13501 cgtcttcaag ggcctcgcgc cgggcctgga ctaccaggtg cagttcttca cccccaccgg
    13561 cttcgacgcc gcgagcccgc gccagcaggg cgccagcaac gcggccgaca gcgacggcgc
    13621 gctctccgac gtcgtcgtgc tctcggccgg cgaatggaac aagacgatcg acgccggctt
    13681 ctacaagccg gtctcggtcg gcgacttcgt ctggaacgac caggacgccg acggcatcca
    13741 ggacgtcggt gaggccggga tcggcggcgt ccgcctgacg ctgaccggca ccacaggaag
    13801 cggcgaggtc atcgtccgca acacgcttac cgcggccgac ggcagctatc tgttcgacgc
    13861 cctgcccccg ggcatctacc aggtcagcgt cgatgccgat aacttcgatc ccgccggcgc
    13921 gctctccggc ttccagtcca gcccgatcgg ccagggcacg gacgccgcgc tggacagcaa
    13981 cgcctcgccg accggcaccg accccgtcac gctcctgtca ggccagagcg acacggatct
    14041 ggacttcggc tacttcaagg ccacggccgc gatcggcgac cgcgtctggg aagacaccaa
    14101 cgccaacggc cagcaggacg acggtgaaac cggcatcgcc gacgccaccg tgcgcctcta
    14161 cacctgcgtc gacggcgccc ccggcaccct ggtcgccacg accaccaccg acgccagcgg
    14221 caactacgcc ttcaccggcc tcgtccccgg ccagtacatc gtcgccttcg agactccggc
    14281 gggctaccag ctcagcaccg ccgacgtcgg cgccgacgcc agcgactccg acgccggcac
    14341 cggcggcctc accggctgct acaccctggc ctcgggcgag accaacaaca ccgtcgacgc
    14401 cggcttctgg cgtccggctg ccatcggcga ccgcgtctgg ctcgacgcca acgccaacgg
    14461 ccagcaggac gacggcgaag ccggcgtcga aggcgtggag gtcgagctct acacctgcgt
    14521 ggacggcgca cccggcgtga aggtcggcgc ctccaccttc accgacgcgg ccggcaacta
    14581 cgccttcacc ggcctgatgc ccggccagta cgtcgtcaag ttcctcaccc cggacggctt
    14641 cagcctctcg ccggtcgatg tcggcggcga cggcagcgac tccgacgccg gcatgggcgg
    14701 cttcaccggc tgctacacgc tcacctccgg ccagaccaat aacacggtcg acgccggcct
    14761 ctaccagggc gccgcgatcg gcgaccgcgt ctgggaagac accaacgcca acggccagca
    14821 ggacgnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnntgaag gtcggcgcct
    14941 ccaccttcac cgacgcggcc ggcaactacg ccttcaccgg actcgagccg ggcgactacc
    15001 tcgtcaagtt catcaccccg accggcttct tcctcaccaa ccagaacgtg ggcgcgaacg
    15061 acacggcgga cagcgacgca gacgccacca ccggcttcac cggctgctac aagctcgaag
    15121 cgggtgagac cgacagcact gccgacgccg gcatcttcaa gcctggcgaa ggcggcgtcg
    15181 tggcgtcgat cgacctcgtc aagctcacca acggaaccga caacaacgcc cccaccgggc
    15241 cgtatctcgc ggtcggcagc accgccacct tccagtacct ggtgaccaac gacggcatgg
    15301 tcgcgctgtc ggacatcgtc ctctccgacg accatggcac gccaggcgac acgagcgacg
    15361 acttcacgcc catcttcctc ggcggcgacg ccgacggcga cggcctgctc gatgtcggcg
    15421 agagctggat ctacgaggcc tccacggtcg tcagcgccgg ccagtacacc aacctcggcg
    15481 ccgtgaccgg gacaccggtc gacgccgacg gcaacctggt cccctccctg ccgcagccca
    15541 ccgacacaga cctcgacaac cacttcggcg cgcgggtggc gatcgacatc gagaagttcg
    15601 tccgcggcgt ccatcaggac accggcggcg gtggcgaagg cctcaccccc ggcttctgga
    15661 agacgcactc cgaatacggc ccggcaccgc tggctggctg gccggagacc ggctactccc
    15721 cggatgacgc ttgggaagcc gtcttcggca tcaacgtacc cggcgcaccg accctgctcg
    15781 atgcgctgaa cgcggcgggc ggcgggctcg acgcgctgct gcgccactcg agcgccgcgc
    15841 tgctcaatgc ggcgcagccg aacgtggact atgcctacac ctcgagccag gtcatctcgc
    15901 tgacccgcga cgccatcctc agcggcgacc tgaaccagat cgagtcggtc aagaaccagt
    15961 tcgtgatgca gaacgagctg ggtgccgacc tcagcacccc cgcaagcggc ggggccacgg
    16021 tcaccacccc gtggttcgac gccgacgccc ccggcaccgg ccccttcatc gcgctgggcg
    16081 gcacggccga gttccggtac gaggtccgca acaccggcga tgtcgcgctc gaaggggtgt
    16141 ccgtgagcga cgaccgcctc tccgggctga gcttcgaggg cggcgacacc gaccacgacg
    16201 gcctgctcga cctcgacgag gtctgggtct accgcggctc cgagctcgcc gacaccgcgg
    16261 gagtggatat cgccaacgtc ggcaccgcaa ccggttcggc gctgggcatc atggcgaccg
    16321 acgccgacgc ggcgcgctac tcgacggctg cgtcgacgca gtcgctgggt gacttcgtct
    16381 ggctcgacgc caaccgcaac ggcctgcagg acggtggcga ggcgggcatc ggcggcatgc
    16441 tggtgaccct gaccggcggc ggcgccgacg gcatcatcaa cggcgtgggc gacaccacgg
    16501 ccatcaccag caccgacgtc gacggctact accagttcga caacctggcg gccggcgtgc
    16561 agtaccaggt gacgttcggc aaacctgcgg gcacggcctt caccatgcgg gacgccggcg
    16621 ccgacgacgc catcgactcc gacgccggcg ccgacggcaa gagccagatc gtcaccctca
    16681 gtccgggcca gcacaacccg tccgtcgacg cgggtgtata cgtactcaat cccgggatcg
    16741 acctcgagaa gaccaccagt ggtccgtcca acgccaaccc gaccgcggcg gattacgaca
    16801 acgaggacac gcccgatggc gcgggcgtgc cggtgctgac cgccggctcg gcggtgacct
    16861 ggacctacaa gctcaccaac accggcaatg tcgactttgc caaggccgac ctcgccctcg
    16921 tggatgacaa cggcacgccg accaacgccg ccgacgacat gtccatcgcc aacggcaaga
    16981 tcgcatacgt gtcgggcgac gatggcgaca acgtgctcga ggccggcgag tcgtggctgt
    17041 acgaggccca cggcaccgtc cagtccctgg gcgtcctggg cgccgccacc acgatcgact
    17101 tctccggcaa caccgcggtc gacggcaccg acggcaacac ccgcagctac agcgccggtg
    17161 gcgtcaccgt gcaggccaac gcctggagcc gcacgaaggg cagcgacacc tggcagaagg
    17221 cctggctggg cgcttacgac gccggcctcg gggtcaccga cagcagcgag agcggcagcg
    17281 gctccaccca caccgtcgac aactacggcc gcgacaacta catcgtcttc cagttctccc
    17341 aggacgtggt ggtcgacaag gccttcctcg gctacgtcgt gggcgacagc gacatgaccg
    17401 tgtatgtggg ctcctccacg gcgcccatca ccgccatgaa caacgccgtg ctcgccggca
    17461 tgagcctcaa ggagttcaac gacaccggct cgacctccgc ccgctgggcc gacttcaacg
    17521 ccggcgacgt ccagggcaac gtgctgatcc tggccgcccg cgacgatggc cacagctccg
    17581 actacttcaa ggtcgaaaag ctggtgttcg aggccgtgca gtccggcggg gtgtacgcga
    17641 acaccgccac ggtcaccgca ccgggcggcc tgagcgactc ggacatgagc cactacgaga
    17701 ccgtccccgc cacccccggg atcgacctcg agaagaccac cagtggtccg tccaacgcca
    17761 acccgaccgc ggcggattac gacaacgagg acacgcccga tggcgcgggc gtgccggtgc
    17821 tgaccgccgg ctcggcggtg acctggacct acaagctcac caacaccggc aatgtcgact
    17881 ttgccaaggc cgacctcgcc ctcgtggatg acaacggcac gccgaccaac gccgccgacg
    17941 acatgtccat cgccaacggc aagatcgcat acgtgtcggg cgacgatggc gacaacgtgc
    18001 tcgaggccgg cgagtcgtgg ctgtacgagg cccacggcac cgtccagtcc ctgggcgtcc
    18061 tgggcgccgc caccacgatc gacttctccg gcaacaccgc ggtcgacggc accgacggca
    18121 acacccgcag ctacagcgcc ggtggcgtca ccgtgcaggc caacgcctgg agccgcacga
    18181 agggcagcga cacctggcag aaggcctggc tgggcgctta cgacgccggc ctcggggtca
    18241 ccgacagcag cgagagcggc agcggctcca cccacaccgt cgacaactac ggccgcgaca
    18301 actacatcgt cttccagttc tcccaggacg tggtggtcga caaggccttc ctcggctacg
    18361 tcgtgggcga cagcgacatg accgtgtatg tgggctcctc cacggcgccc atcaccgcca
    18421 tgaacaacgc cgtgctcgcc ggcatgagcc tcaaggagtt caacgacacc ggctcgacct
    18481 ccgcccgctg ggccgacttc aacgccggcg acgtccaggg caacgtgctg atcctggccg
    18541 cccgcgacga tggccacagc tccgactact tcaaggtcga aaagctggtg ttcgaggccg
    18601 tgcagtccgg cggggtgtac gcgaacaccg ccacggtcac cgcaccgggc ggcctgagcg
    18661 actcggacat gagccactac gagagcgccg ccaagatcgt tgccgccccg aagttctttg
    18721 tcgtcgatca ggccaaggat ctgagctacc agtacgccga cggtggcgac ggcctgggca
    18781 gcttcgcgct ggcaaacacc gatccgcgcg acatcgccgc caacgcggac ggcagcctgc
    18841 tgtgggtgct cgaccgcgac aagaacgtgg aggtctacaa gggcgacggc acgcagctcg
    18901 ggcagtggaa ggcctacgga ctgggcaccg aaccggaggg catcaccctc gacggcaagg
    18961 atctctggat ggcggaccgc accggcaagc tcaactggta cgacaatgcg gccacccgca
    19021 catccggcac cgacagcccg gaattgagct tcacgctctc gctcgacggg aacctcaagg
    19081 gcatcgtgac cgacggaacc tacctgtggg ccgtcaccga ggggacgtgc gactacgtgt
    19141 atcggttcaa gatcgtgcgc gactggtggg gcaatccgag cggcttgagc cagagcggcg
    19201 ggtggcagct ccccaccgcg aacaccaagc cgaccggcat cacgctcgac cccagcggca
    19261 agtcggacag cctgtggatc gtggatgagt cgaccgacac ggtgtacgag tacggttacg
    19321 gccgcagcca gacctggggg gtcggaacga tcaccgcgaa gttcaagctc tcggccggca
    19381 acaccgcacc acaaggcatc gccgaccccc tgcccgccgg ggcggaggcg ttcgacctgg
    19441 ccgagatctc cgctgccgcg gggctggaga cgacgcagcc cgatccgtac gcgggcgact
    19501 tcgtcacccc gctcttcgac gacgcgatcg ccttccacga cgccggcatc gtcgggacga
    19561 gtgcacaaag cgaggccacc ctggcactgc ttcacgcttg agcccggatc gactgcgcta
    19621 agatccggtt aacgcaaggc tacggtcggg aacccttccc ggccgtagcc ttgcgtgcga
    19681 ttcttccaca tgcctgtcgt cccggaacgg tgggcaagtc ctggaaccta ccagccttcg
    19741 cgcacgggga cgacgaatcc gatgacaaag cagacgttcg gccagccggc cggcggcgaa
    19801 ctgaaggagg ccttgcaggc cctgcggaac gccttcacta cggtgggcgc cttcagcggc
    19861 ttcatcaacc tgatgatgct cgccccggcg ctctacatgc tgcaggtgta tgaccgcgta
    19921 ctcggctcgc gcaacgagac cacgctggtg atgctcaccg tgctcgtcgt cggggcgctg
    19981 ctgttcatgg ccgcgctcga gagcgtgcgc ggctggatcc tcgtgcgcgt cggcgcccgc
    20041 ctggatgcgc agctcaatgg tcgcgtgttc accgccgcct tcgagcgcaa cctgcagcag
    20101 gccggcagca acaccgcaca accgatccac gacctcaacg cggtgcgcca gaccctcacc
    20161 gggtcggccc tgctcgcggc cttcgacgcg ccctggctgc cgatctacct cgtggtgatc
    20221 ttcatgatgt cgccactgct cggctggttc gcgctcgccg gcgcgatcgt gctgctcgtg
    20281 ctcgcggtgg cgaacgagcg catctccaag ccccgcctgg acgaggcaca gaaattctcc
    20341 atgcagtcgc accaggcact cgtcagccac ctgcgcaaca gcgaggtgat cgaggcgatg
    20401 ggcatgctgc ccgccatccg ccagcgctgg cacgcgctgc accgccagca gatccacgcc
    20461 caggcgctgg cgagcgaccg cgccgcgatg ctgagtggcg caaccaagtt cgtgcgcatc
    20521 gccatgcagt cgctgatcct cggcttcggc gcgctgctcg tgctcgagga ccagatcacc
    20581 gccgggatga tgatcgccgc ctccatcctg ctcggccgcg ccttcgcacc gatcgagctc
    20641 ctggtcggca actggaagca gatcgtctcc ggccgccagg cctacgcccg cctgcaggaa
    20701 ctcctgcagc gccaccccgc acgcgggacc agcatgagcc tgccacggcc gcagggtcgg
    20761 atcaccgccg agggcgtctc ggcgatgccc ccgggcacgc gccgcatggt gctcaagaac
    20821 ctcggcttca ccatcgcccc gggcgaggtc gtcgcggtgg tcggtcccag cgcatcgggc
    20881 aagtcctcgc tcgcccgcct gctcgtgggt gtctgggcgc ccgcggcagg gagcctgcgc
    20941 ctggacggcg cctcggtcta cgactggaac aaggacgagc tcggccccgc actcggctac
    21001 ctcccgcagg acatcgaact cttcgacggg acggtggcag agaacatcgc ccgcttcggc
    21061 gaggtcgact ccgagcgcgt cgtcgacgcc gcccgcaagg tcggcatgca cgagcacatc
    21121 ctgcacctgc cgcaaggcta cgacaccccg ctcggcgccg agggcagcaa cctgtcggcc
    21181 ggccagcgcc agcgcatcgg actggcgcgt gcgctctacg gcgatcctgc cctcatcgtg
    21241 ctcgacgagc ccaactccaa cctcgacgag gcgggcgaga aggcgctgct cgaagccctg
    21301 ctcggcctca aggcgcgcgg cgccacggtg gtgatcgtca cccaccgcat gtcgaccctg
    21361 gccgccgccg acaaggtcat ggtgctgacg gacggcaccc tcgccgcctt cggcccgcgc
    21421 gacgaggtct tcaagccgac cccggcaaca acgaccgcgc catccacacc caatgccacg
    21481 cccgccaatc ggcgcgtggc gaacgtggtc ccaggcgcac cggtcctcgc accgggagcg
    21541 gcacccggcc gctgagtccc gaccgctgag tccgtcccgc cacccagcca ccgcaccgat
    21601 accggaatcc cccgatgccc ccttcccctc ccgattccag cgcgccgccc ggcggccagt
    21661 ccggcagcgc agctcacacc gagctcagcg actcccatgc acgccgctgg ggctggctcc
    21721 tggtggtcgc cggcttcggc ggcttcatgg cctgggcggc actcgccccg ctggactccg
    21781 gcgtcgccgc tccgggtacc gtggtggtct ccggcaaccg caaggccgtg cagccactgg
    21841 tcggcggcaa gatcgccgag ctcgcggtac gcgacggcga cgcggtgcgt gccggccagg
    21901 tactggtgcg gctggacgac acccaggcgc gctcacagct cgacgtcgcg cgcgggcagt
    21961 ggtttaccgc cagcgcggtg gaggcccggc tggtcgccga acgcctcggc cacccgcaga
    22021 tcgagttccc cgcggcactg cgcgaggccc acgccgaccc gcgcgccagc gccgcgatgg
    22081 cgctgcagcg cgagctgttc gtcacccgcc agcgcgcact ggcgagcgaa ctcgccatcc
    22141 tcgaggagag catccgcggc ctcgaagcgc aattgcgcgg ggtggaggcg tcgtcgcacg
    22201 cgcgccgcac ccaggtcggg ctgctgcgcg acgagatcgc acgccaacgc ggcctcgtcg
    22261 acgaaggctt ctaccctcgc aaccgtctct ccgaacagga acgcagcctg gccgcgctca
    22321 acgccgcgat cgccgaggac gccggcaacg ccgggcgcat ccgccagcag atcgccgaga
    22381 cccgttcgcg catgatcgcg cgcgagaacc agcaacgcca ggaggtggag tcgcagctca
    22441 ccgaggtcca gcgcgacgcc ggggcgctcc tgagccgcat cgaggcgctc gagttcgacc
    22501 tgcgcaacac cgagatcgcc gccccggccg acggcctcgt cgtgggcctc gcggtgcata
    22561 ccgtgggcgg cgtggtcggc gtcggcaacc cgctgatgga gatcgtgcct gccgacgagc
    22621 cgctcaagat cgacgcgcag atcccccctc acctgatcga ccacgtgcgt gccgggctgg
    22681 aggtggacat cctcttcccc gccttcaacc gtgccaccac acccaacgtc gccgggcgcg
    22741 tgctgcaggt ctcggccgac gtgctggtcg agccgcaaca aggcatccag tacttcaagg
    22801 cggtgatcga ggtgaccgcc gagggcatgc acaagctgcg ccagtacgag atccgcccgg
    22861 gcatgccggc cgagatcttc gtgcgcacgg gcgagcgcac cctgctcaac tacctcgtca
    22921 agccgctcac cgaccggctc aagggcgccc tgaccgaacc atgatgcgca tcgactcccg
    22981 ccccctcgcg ctggtgctcg cgctggcctt gacaccagcg cccgcgctcg ccgccggcgc
    23041 atttgccacc gcgttcgacg ccgcacgcgc caacgacgcc gcctaccgtg ccgcccggca
    23101 tgaactggag gccggcgaga cgctcgtgcc gatcgcccgc gccggcctgc tgccgagcgt
    23161 gacggcgagc ttctcggagt cgcgcgtacg cggcgagcgc gaatacgccc ccccacgtcc
    23221 caaggacgat ctcgattacc gcaaccctgt ctttgcgctg cagttgcgcg cgcccctgtt
    23281 caacctcgag gcgtacagcc gctacgccgc ggcgcaggcg cagaccgaag gcgcgcgcgc
    23341 gcgcttcgct gccggcggcc gcgaattgct cgaccgcctc ggcctcgcct acgtgcagcg
    23401 cctgttcgcc gaggagacgc tcgccctcgc acgcgtgcag gtcgatgccc tcgagaccca
    23461 gacgacgatc gcccgccgtc ggctcggtgc cggcgaaggc acgcgaaccg agctcgccga
    23521 cgccgaggcc agcctggcca gtgcgcgcgc cgaaaggatc gccgccgagg accagcgcga
    23581 actcacccaa cgcgcgctcg cacgcatcac cggtagcgag gcactcgcct tgcgcgccct
    23641 gcccgcacac gcggcccccc tgcttcccgc cacccgcgca ctgtccgaat ggatcgcgct
    23701 cgcgcgcgaa cacaacccga cactcgccac gcgcgagcgc gagatcgagg cgctggagca
    23761 cgagatccgc cgcaatcggg ccggtcacta tccgcgcgtg gatctcgtcg ccagcgcggt
    23821 gaacgccgag aacgaatcga tcagcacgct cgaccaggag acacgccagt acagcgtcgg
    23881 ggtccaggtg aatatcccga tctacgccgg cggcggcgta gacgcctcgg tgcggcgcgc
    23941 tgccgccgaa ctcgcacgcg cccaggcacg cctcgacgac gacttgcaaa gcctgcagct
    24001 cgatgtcgaa cgccagttcc gcaccatcga gagcggtcgg gcaagactgg ccgcactcga
    24061 cgacgccgtc gcatcgagcg aactcgccct gcaaggcgcc cgccgcggcc agagcgccgg
    24121 cgtgttcagc tcggcggacg tgctcgacgc cctgcgtcgc caccacagcg cccgccgcga
    24181 cgccgcgcag gcgcgccacg aactgctgat cgcgcggatc cgcctgcagg cgctcgcggg
    24241 aatcgccgag gaagagatcg tcgccgacgt ggaccgtctg ctgactgcgg agctggttgc
    24301 cgatcggcgt tgagcgtacg ccggcatttc gaggtggccc gtcgaacgga cgttttgcgg
    24361 acgtgcgccc gggacggcgc cgaggaggtg gcggaggcgg tgagattcga actcacgagg
    24421 ggcgtaaacc cctgacggtt ttcaagaccg ttgcattcaa ccgctctgcc acgcctccgc
    24481 aaggacccga agtataccac cgcgacgcgc ccgcatcgga gggcatcgcc ggtgatcacc
    24541 cctgcccggc cagcccctcg gacgcgcgct cgaagagggc gacggactcg acgtgcgagg
    24601 tctgcgggaa catgttggcg atccccgccg cggcgagccg gtagcctttc tcgtgcacca
    24661 gcaccgcggc gtcgcgcgca agcgtcgccg ggttgcacga cacatacacg atgcgggcgg
    24721 ggccgcgtga cggatcgatg gccttcacca cggcaatcgc gccctcgcgc ggcggatcga
    24781 tcaacagctt gtcgagccgg ccgagcgcgg ccaggctgtc ctcggtggtc tcgaacagat
    24841 tcgcggcgtg gaattcacaa agcgccgcga gcccattgcg cgctgcgttg gcatgggcgc
    24901 gctcgaccag ggcctcgcta ccctccacgc ccaccacctc ggcgccgagg cgcgcgatcg
    24961 gcaggctgaa gttgcccagc ccgcagaaca ggtcggcgat gcgctcgccc gggcgcggat
    25021 cgagcagctg catcgaacgc cggatcagca gtcgattgat gtccacgttc acctgggtga
    25081 agtcggtcgg acgaaaatcc agccgcaagc cgaactcggg cagggtgtag aacggagatt
    25141 gcgcgcctgc cgggtgcagc ggccgcgccg aatccgggcc ggcgggctgg atccaggcct
    25201 ggatgccttc ggcgtcggcg aaggcggcga gccgcttctc gtcggcggct gagaacggca
    25261 gcaggttgcg gaacacgaac acggtgctgt cctcgcccac ggcgatctcg acctgaggca
    25321 ggcggtcggc gatcgacagc ccggccagca tcgtgcgcag acgcggcagc agggccgaga
    25381 tcgccagcgg cagcaccggg caggtgcgca tgtcgacgat gtagctcgaa cggcgctcat
    25441 ggaatcccac gcgcagcccg cccttgctcg gcaccatgcg cacgccgagg cgcgcacgat
    25501 agcggtagcc ccacgcgggg ccgtggatcg ccggcaggat ccgcccggga cgcagcttgc
    25561 cgatgtggcg cagcgcgtcc tcgaggatgc gctgcttcac cgcggcctgc gcatccgcat
    25621 ccagatgttg catggagcag ccgccgcaca cgccgtaatg cgggcagcgc ggcgccacgc
    25681 gctgggcgct cgggcgcagc acccgcaccg tctcgccctg ctcatagctc ggtttggccc
    25741 gccgcaccac atattcgacg cgctcgcccg gcagggcgcc ctcgacgaac accgccttgc
    25801 cctcgacgcg ggtcacgccg cggccttcgt ggtccaggga atcgatcttg gctattggca
    25861 tggtcatgct ggaggttccg ggagcgcgcg attctaccgc gccacgcccg cgtggatgtc
    25921 cgcttccggc aaagtctcct tacctttgag ccgcgcttgc gcggcgccac cgcatccgga
    25981 cgacatgaag ccgcatgcta gaatctttgt gcattgcggc aatcgcaacg atcgccggac
    26041 acccccagag atcacgggaa cgggccgcat gcacccaccc ccagaataag gaagacagac
    26101 catgaagcat tccatcctcg ccgtcgccct cgtcgccctc gccgtctccg cctgcggcaa
    26161 gaaggaagag ccggtcgcag tccagccggc cccctcggca caggagcaga tgaaggaatc
    26221 tgccgcgcag gcggtggaag cggccaagga aagtgcaaaa gccgctggtg atgccgccgc
    26281 agcgggcgcg caggccgtca agcaggaagc cgccgtcgcg gtcgaggcga ccaaggaagc
    26341 cgccgctact gcggccgaca aggccgccgc cgccgcagat gcagccgcgc agaaggccga
    26401 cgccgtcgcc gacgcggcgg cccagaaggc cggagccgcc gtcgaggcgg tcaaggacgc
    26461 tgccgccgaa gccaaggccg acacggtcga tgccgccgcc caagccaagg ctgccgccga
    26521 agctgcggtg agcgctgcca aggaatcggc tgcgaagtaa cagttcgcac cacgccccga
    26581 atgaaagaag ccggcttcaa gccggctttt ttcatgctgt cgccgccacg ggcgatactg
    26641 tccccgcagc agggtgacgc ggcctcgtcg agaccccgtc cccggcacag ctcagcgcaa
    26701 ttgctcctgc agcaggccga gcatgcggcg tgcggtctcg gagttgtcga gcccgccctc
    26761 gcgggtgagc acgctgaccc gcgaagcgtc gccctggccc tgcacgcgca ggcgatactc
    26821 gctaccgccg gcggcgggct tgtcgtcgct gcgccagaac gccaggcgcg agaggagccc
    26881 cttgtccgga ctgcggttgt ccgcgtcggg gtcgacgtaa cgcacgaagt aaagcccctg
    26941 cgcacggtca cggtcctcga cggtgaagcc gatccggtcg agcgccaggc cgacacgacg
    27001 ccaggcgcgg tcgaaggcct cgtccatcac cagcatcacc tggccgtcag atgcggaggc
    27061 gatgcgcgcc cgctccgaag cctgctgcgg cgtggcgatc gcggcctcgg cgcggacctc
    27121 ctcggccccc aggcggacca tcaggcggcg cagcatctcg gcctcgagct cggggtcggc
    27181 cggacgcggc tgccagatcg tggagtcctt ggcctcggtg gggtagatct ccatcatgcc
    27241 gcggtgggag atgtagacct ccacggtgcc cgcctccttg ccctgctcga ggcgggtgcg
    27301 gaacttgtcg cgctcggggg tcgagaacag tccgtcgaaa accttgccga tgctggatcg
    27361 gatgaagtcc tgcgggatct tggcgcgatc ctcggcccag tcggtctcca tgacgccgat
    27421 ctcgggactg tcgatgttga ggatgaagcc gagttcgagc cagaagtcct tgatctgcgg
    27481 ccacagctcc tccggcgtgc cgcccaccac cagccagcgc tgactgcccg cccgctcgac
    27541 gcgcatggtg tcggacttgg cgagcacctc tggaccgctg gagacctgcg caggctggct
    27601 ggcgcggtct gccgtgtagg cggagtaggt ggcgacgccg cgcggggcga cgtccggcac
    27661 ggcgaagcgg tcgtcgcgct gcggcgcagt gaggtcgggc gggatctcga gcggacgctc
    27721 gatctgtttc gcgctcttgt agtcgatgcg cttggattcg agcaacgatc ccgaacaacc
    27781 gccgagcgcg atcgagagcg cgagcaggga cagggaggtg cgcttggagc ggatcatgga
    27841 agtcctgggc agaaaggttc ggatcaggcc tggatgccgg ccttgcgcat cgccgcgcgc
    27901 acgcgctcgt gatgggctgc ggacagcggg gtcaggggca ggcggatgcc atcgccgacc
    27961 agccccatgc gcgccaccgc ccacttcacc gggatcggat tggcctcgca gaagaggtcg
    28021 cggtgaaggc cggtgagcgc ggcgttggtc tcgcgcagcg tgcgcatgtc gcccgcggcg
    28081 gcggccgcgc acagggcatg catcgcgcgc ggcgccacgt tggcggtcac cgagatgacg
    28141 ccatggccgc cgagcatcag gaacgcggcc gaggtcatgt cgtcgccgct gtacagcgcg
    28201 aagtccgccg gcgcacgctc gatgaggtcg caggcgcggt cgaggttgcc ggtcgcgtcc
    28261 ttgaggccga cgatgttggg cacctcggcg aggcgcagca cggtgtcgtt ggccaggtcg
    28321 gcaacggtgc ggcccggcac gttgtagagg atgagcggca gctcgaccgc ctcggcgatg
    28381 gtgcggaaat gccggtagag gccttcctgg gtgggcctgt tgtagtacgg caccaccgag
    28441 agatgcgcgt tcgcgccggc ctgcgcggcg aagcgggtga gctcgaccgc ctcggccgtc
    28501 gagttggcac cggtcccggc gatcaccggg acgcggcctg cgcagtgctc gaccgccaca
    28561 cggatgagct cgcagtgttc gcccacggtg accgtgggcg attcgccggt cgtgccgacg
    28621 atcacgatgc cgtcggtacc ttcggcgata tgccagtcga tgaggctgcg caggcggggg
    28681 aagtccaggc tgccgtcgtc gtgcatgggc gtgacgatgg cgacaagcga tccggtaatc
    28741 atggcgtccg acagtgaaat aaagctggga ttctaaccga tcgccgcgcg cggtcgagcc
    28801 cgccgctgtt acaggacgcg gccggcaggc ccgttgcgcg ggcgtgccgg ccggcggcag
    28861 cgaggtcacc ccgaagggcg cggatcaaag atcggccagg gtcttgatgt gggccaccac
    28921 cgagcgcgcc agcgacgaca gcgagtaacc gccttcgagc accgagacga tgcgcttgtg
    28981 gccacaggcc tcggcgacgc ccttgatctg ctgcgtcgcc cagatgtagt cggcctcgag
    29041 caacccgagc gagcccatgt cgtcctcgta gtgcgcgtcg aagccggcgg agatgaagat
    29101 catctgcggg ctgtggctgc gcagcgccgg caccacgatg tcgccgaaca cctggcggaa
    29161 ggcatcgccc cgcgtacctg ccggcagcgg cacgttgcac atgtgagccg gggggttctc
    29221 ggtgccgcaa tacgggtaga agggatgctg gaagatcccc gccatcatga cccgcgggtc
    29281 gttgcggaag atgtcctcgg taccgttgcc gtgatgcacg tcgaagtcga cgaccgcgac
    29341 gcgctccagc ccgtgcacct cgagcgcatg gcgtgcggcg atggcgacgt tgttcatgaa
    29401 gcagaacccc atcgccttgg cgcgctcggc atggtgaccg ggagggcgca ccgcgcagaa
    29461 ggcgttctcg atctcgccct tcatcaccag gtcggtggcg tagacccccg caccggcaga
    29521 gcgcagcgcc gccttcatcg tgcccgggct catcgccgtg tcggggtcga ggtggcgaat
    29581 gccgtgctcc ggcacgctct cgagcaggtt gtcgaaatac tcggccggat gcacgcgcag
    29641 gatgtgctcg cgctcggcca gcggcgcatc gaagaaggac acgtacatat cgagccccga
    29701 ggcgatcagg cgatcattga tcgcagacaa ccggtcgggg cactcgggat gcatcgcgcc
    29761 catgtcgtgc agccagcagt cacggtgagt aatgaatgct gtcgtggtca tactcctccc
    29821 tctcgcctcg cggacgacgg aaacggcgcg acacgcaccc cgttccgact ctggcggccg
    29881 ccgaccgtgt tgcgtccgat cgtcgggccg cttgcctttg tcgtctatta tcaccgcttc
    29941 ccggccaatt tcacagtgcg ccacgatgcc cctgcaccat gcgaatcgtc tgctggaagc
    30001 cgcctcgcga atcatcctcg gcaaggagcg cgaactccgt ctcgccctcg cctgcctgat
    30061 cgcgcgcggc cacctgctca tcgaggacgt gcccggcgta ggcaagacca cgctcgcaca
    30121 cacgctcgcc cgcctgatgg ggctgcagtt ccagcgcatc cagttcacca gcgacctgct
    30181 gcccgcggac atcctcggcg tgtccgtctt cgaccgcgac accgccgcct tccgcttcca
    30241 ccccgggccg gtgttctccc agctcatcct cgccgacgag atcaaccgcg ccacaccgaa
    30301 gacccagagc gcgctgctgg aagccatgga ggagcgccag gtcaccgccg acggccagac
    30361 ctgcgcactg cccgaaccct tcttcgtgat cgccacgcag aacccggccc accaggtcgg
    30421 caccttcccg ctacccgaga gccagctcga ccgcttcctg ctgcgcatcc gcctcggcta
    30481 ccccgatccg caggcggagc gtgcgctgct gatgggcgag gaccggcgcg ggttgctcga
    30541 gcgccaccag gcggtcatcg gcccggcaga gctgctcgag atgcagcagg cggcacaggg
    30601 cctgcacgtc gccgaggccc tcgtcgcgta tgtccaggcg ctgctcgcgg cgacccgcaa
    30661 cagcgcggag ctcgccggcg gactgagccc gcgcgccggg ctcgggctgc tcgccgcggc
    30721 ccgcgcctgg gccctgctcg acggtcgtga tcacgtgctg ccggaggatg tgcaggccct
    30781 cttcccacac gtcgccgcgc accgcgtgca cttggccggc gatggccgcc cagtgccgcc
    30841 ggcgacgctg ctacggctgc tgcaggcggt cgcagtgggc tgatggcgcg cctcatcacc
    30901 actgcattcg tccagcgcct gcgccatagc gtcgaccgct ggctgttccg cgtcggcgcc
    30961 gcggagccgg caccgatccg cctcggccag cgccggatct acgtgctgcc gagtgccgcg
    31021 ggcatcgcct tcgccctcgc tctgctggtg atgctgctcg cggcgatcaa ctacaacctg
    31081 agcctcggct acgcgctcgt gttcaccctg ggcggcagcg cagcatcgag catgctgcat
    31141 gctttccgca acctttacgg cctatcgatt cgaccgggac gttgcccacc ggtgttcgcg
    31201 ggtgacacgg ccgtattcac cctcctcgtc gacaaccccg ctccccgccg gcgcccggcc
    31261 ttgcgcctgg gcgcgcaagg gcaatgcagc agcttcgagc tccccgccgc gcaggagacc
    31321 gccatcccca tcgcatgccc cgcgccccgg cgcggccggc tcgtactggg acgcagcacg
    31381 ctcgagacgc gctggccact cgggctcatc cgcgcctgga gcgtgttcgt gcccgcggcc
    31441 gagtgcctgg tgctgcccac cccggaagcc gatccgccgc cgctgccccg cgacggggcc
    31501 ggcgatactg cgcccggcag ccggcgtaca ggcgagggcg acgacgactt cgccggcctg
    31561 cgcgcgcatc gcagcgcgga ctcgccacgc cacgtggcgt ggaaggtgct cgcgcgcggc
    31621 ggcccgatgc tgaccaagga gttcgccgca ggacaggggc gcgaactcct gctcgactgg
    31681 gatcacctac cgcccgggtt cgacgacgag cgccggctgt ctcggctcac cgcctgggtg
    31741 ctcgccgccg agcgcgaagg cctgcgctac gcgctcgccc tgcccggcgt ccgcatcccc
    31801 gccgcggccg gcggcgctca tcgcgaacgc tgcctgcgac agctcgcgct gcatgggctt
    31861 gcggatgcga cagcggggga acaggcatga gcactgcccg ctcgtcacgc cggctcggcc
    31921 tcttccgcca cggcggcgcg ctgccccgag aacgcgtcac cccgccggcg ccgacgctcc
    31981 gccgcaacca gggcgcgtgg ctgctcggcg ccgcagcaat ggcgatcgcc ccgcattcgg
    32041 tctggcttcc cgcatggatc acggcgctcg gcctcgccct gctggcgtgg cgcgcactgc
    32101 tgctgtggcg cggtagccgg ccaccgccgg gcgtattgct gttcgcgctc gcgcttgccg
    32161 tcgcggcggg ggtacggctg gagttcggcc acttcttcgg ccgcgagccc ggggtggccg
    32221 tgctggtcct gctgctcggc ctcaagttgc tcgagacgcg cgcggcacgc gacatccgcg
    32281 cggcggtgct gctctgcctg ttcctgcagc tggcgctctt cctcgaggac cagtcgctgc
    32341 cggtggccgc gctggtcctc ggcgggaccc tgctcgcgct cggtgctctg gtcgcgctcg
    32401 ccgaccctga cggcagccag cgcgagcacc tgcgcaccgc ggccgccctg ctcgcccagg
    32461 gcataccctt catgctcgtg ctgttcgtgc tcttcccgcg catccagggc cccctgtggg
    32521 gcctgccggc ggatgcgttc tcggcgcgca ccgggctgtc cgagacgatg cgcccgggct
    32581 cgatcagcgt actcggccag tccgaggcga tcgccctgcg cgccgccttc tccggtccgc
    32641 caccgcctcc ggcgcagcgc tactggcgcg gcccggtgct cagccgcttc gacggccgcg
    32701 aatggcgtgc cgaagcggtc gtcgagtccg cctcgcccgc ctacccgctg cagggcgagc
    32761 gcatcgacta cctgctcacc atcgagccgc accagcgccg ctggctgctc gcgctcgagc
    32821 acccgggctc ggcgcagccg gcgatccgct acaccagcga cctgcgtgcg ctcgccgccg
    32881 aacccttgcg ggcgcgcgca cgattcgcgc tcggagccta tccgcagacg caagcagggg
    32941 tcgaggaatc acccgcggta ctggccgcag ccaccgccct gccggccgac agcaacccac
    33001 gcagccgcga actcgccgcc gagctcgcca ccggcgcgcg cgaccacgcc gagatcctcg
    33061 agcgcgtgct cgcccggcta cgcggcctgc gcctcgccta caccctgcgc cccccgctgc
    33121 tcggccgcca taccgccgac gagttcctgt tcgacacccg gcgcggcttc tgcgagcact
    33181 tcgcctccgc cttcgccgtg ctcatgcgcg ccgcaggcgt accgacgcga atcgtcaccg
    33241 gctaccaggg cggcgagctc aatccgatcg acggtcacct cgtggtacgc cagtccgacg
    33301 cgcacgcctg ggccgaagtc tggctgcagg ggcgcggctg gctgcgggtg gatccgaccg
    33361 cactcgccgc ccccgagcgc atcgacggcg ggctcgccgc ggcactcgcc ggcgcgggcg
    33421 agctcccttt catgctgcgc accgacatgg tctggctgcg cgaccttcgc caccgctggg
    33481 aagccgtcgc caacctgtgg aaccagcagg tccttggcta caatcccgag cgccagcgcg
    33541 aactgctcgc ccgcatcggc ctcggcgcgg acaggctggc acggaccctc ggcgtactgg
    33601 ccggcgcagc ggtgctgctg ctcgccgccc tctacggctg gagcctgcgc ggcgcgcgca
    33661 cgcgcgacgc cctcgcccgc gaatgggagc gcttctgcgc gaggatggcc gcgtgcggcc
    33721 tgccgcgccc accctggcag ggcccccttg actatgccga ggcgctcgcc gcgcacttcc
    33781 ctgcacacgc ccgggaactg cgcgagatct gcgtgctcta cgcgagcctg cgctacggcc
    33841 cgcacgcccc ggaggaggat ctccggactc tggaaaaccg catcgcctca ttgcgactca
    33901 aatgaactcg acctcgcacc aaacctcgcg cgccgccgcc gcaccgccag ccgcgacccg
    33961 gatccgcccg ctcggcaagc tcgtcaccgc cctcgcgctc gcaatcgcgc taggcacgcc
    34021 cgcggccgcg cacgcatcgt atgcagggcg cgaggacgct cgcaccttcg ccgcggagat
    34081 cgccagccgc catgcgctcg acgccaccga gatcgaacgt gccctggccg gcgcccgtca
    34141 cgatcccgag gtgatccgcc tgatcactcc acccactcgc aagggcgtgc gctcgtggca
    34201 ctcctaccgc gcgcgcttcc tcgaccgcac ccgcatcgac ggcggcatgc gcttctggcg
    34261 cgagcacgcc gacaccctcg cgcgcgccga gcgcgagacc ggcgtcccgg ccgaggtgat
    34321 cgtcgcgatc atcggggtgg agaccatcta cgggcgcaac accggcaact tcgagaccct
    34381 ctcgacgctc gccacgctcg ccttcgacta cccgccgcgc gccgagctct tccgtcgcga
    34441 gctcgaagcc ctgttcctgc tcgcacgcga acagggacgc gacccggcga gctactacgg
    34501 ctccttcgcc ggcgcgctcg gctacccgca gttcctgccg agcagcatgc gcgcctacgc
    34561 gctcgatttc gaccatagcg gcgccatcga cttcgagtcc gatccgatcg acgccatcgg
    34621 cagcgtcgcc aactacctgc gcgcgcacgg ctggcaggcg ggcgcaccgg tcgccgagcg
    34681 cgcccgcctg tcgcccgcca ccgataccgc cagcctggtc gcggccggga tcgaaccgac
    34741 cctcgcaccc gccgtgctcg ccgacaacgg cgtcaccacc gccgacggcc gcacagccgc
    34801 cgccgtcgcg accctggtcg acctggagac gccaggctcc ggcaccgagt actggctcgg
    34861 ctaccggaac ttctacgtca tcacgcgcta caatcgaagc agtttctacg ccatgtcggt
    34921 gttcgagctc gccgaggcac tgcgcctggg ccggctggtc gaggagatcc gcgccgaacg
    34981 ccgctgaagg atccgcccat gcctgcaagc gccccaccgc cgaccgtcga ccagaccacc
    35041 ctgcacccgg cgccgctcgg cctcgccgac ctcggcgggg cgctccgctt cggccttgcg
    35101 cagttccgcg cgattccaat gctgagcatg gctttcgcgc tgctcttcgt ggcgatcggc
    35161 gcgctaatgt tcgggctcct ggagttcggc gcgatcgcgc cgatgagcct gtcgctcgcc
    35221 gggggtttca tgctcgtggg cccgatcctg ctcgccggct tcttcggcgt ctcggacaag
    35281 ctgcgcaagg gccgcaatcc gagcttcggc gacatctgga gcggcttccg ccagatgccg
    35341 cgcggcggct gggtggtgtc cttcgtgtgt ggcttgctct tcctgatctg gatcaccgac
    35401 gcaggcatcc tctacggctt catggtgggc cgcgagccga tcggcttcct gcgcctgctg
    35461 cgaatcgagc aggtcgtgct cgattacgcc ggctacagcg caatcatggg cggcgtgctc
    35521 gcgttcatcc tcttcgctgc ctcggccttc tcgatcccgc tgatctacga cggccgcgcc
    35581 accctggtct cgggcgtggt ggcgagcgtg cgcgcggtct tcggtcgctt cggcgtgatg
    35641 atgtgctggg ccttcctgct cgccgcggtg atcatgggca gcatcatggc gcttcccctg
    35701 ctgctcgtga gtctgccggt gatggcctac gcgagcaggg agctctacta ccgcgtcttc
    35761 ccgctggctt gaggcgcgct ctgcgctcgc ctagagcagc gcgtcacgcg ggattccgcg
    35821 gcggcgcagg atgcggcgca gttgcccgag cgcttcgagc tggatctggc ggacgcgctc
    35881 gcgcgtgagc tccaggcgct cggcgagttc ctccagcgtc aacagctcgc actcgtcgat
    35941 gccgtaacgg tggcggatca ccatgcgctg cttgtcgttg agcatggcga gccattcgcg
    36001 cacgagctgc tcgacttcgg agcactggat ctgcacgtcg gcgctcgcct ggtgttcgtc
    36061 cgcgagcgac tcgccgatcg acagtgtcgg atcgatgtcg agcggcgcgt ccagcgaagc
    36121 cgtatgttcc ccgagcgcga ggatgctgcg aacctcttcg atcgtcttgc cgagccggtt
    36181 cgcgatctgc tcgagcgagg actcgccgtt gcagtcggcc tcgatgtggc gctgcgcgcg
    36241 caagacctgg ttgagctcct tgaccacgtg caccggcagg cggatcgtgc gcgactggtt
    36301 catgatcgcg cgctcgatgt tctgccggat ccaccaggtc gcgtaggtcg agaaacgaaa
    36361 accgcgctcg ggatcgaatt tctcgagcgc atgcatcagc ccgaggttgc cctcctcgac
    36421 caggtcgagc agcgggatgc cacggttgag gtagtgcttg gcgatattga cgacgaggcg
    36481 caggttgcgc tcgatcatcg tctggcgcgc atcgaaatca cccatccgca cacggcgagc
    36541 gatcacgccc tcctcctctg cggtcagcag cgggttggcg ccgatctcgt tgaggtagag
    36601 ctgggtgacg tcgctgaaga actcgttctc gacgaccggg ggagcctgaa acgagaacac
    36661 ctccacctca ggtggaagat ccggttcctg ctgcctctcc agctcatcaa gattgcccgg
    36721 ttcttccatc ctcgccctcc tcagcgcgca ggcagatatc cggtcgggtc gaccgccttg
    36781 ccctgcttgc ggatctcgaa atgaagcttg ggccggtcgg cttccgaact gccgagttca
    36841 gcgatcttct ggccctgtgt cacctggtcg tcttccttga ccaggagctt gtcgttgtga
    36901 gcatacacgg agttgtattc ctgattatgc ttgatcacga tcaacttgcc atagccccgc
    36961 aggccacttc ccgcataaac aaccttgccg gcggccgcag cgtaaaccgg ctcgccgacc
    37021 gctccgccga tatccaggcc cttgttggat gactcgttga aaccggcgat caccgtaccg
    37081 gatgccggcc atttccactg cccccccaca gccgacggcg gcgtctcgac cgcgactggc
    37141 ggcgaagcct ccaccggcgc cggctcggcc accggcgccc gccctccgac aggctcgcgc
    37201 acggtcggaa ccgtgccggc gagcgagccg gtcgcgggga ccggggtcac cacggcccca
    37261 cccgatcccg cgatggctcc cgccgccgcc gacggggaca cgcgcagggt ctggccgacg
    37321 tggatctggt cgggatccgt gatccggttc cacgacacga ggtcgggcag cgtgacgccg
    37381 tattggcgtg cgatgccgag caaggtctcg ccgggccgga cggtgtgata accggtactg
    37441 ggcgagaccg aagccgccgg cgccgaggag acaccgctgc cgtcgcgcac tggcgcggtc
    37501 ccctgcgagg cgcagcccgc aagcagcgct gcagcgagga gggcgatgag ggaaggaatg
    37561 ttcttgtgca tcgaaaaata ccgtgttcag tcagtacccg cgatgagcgg aacgaagcgc
    37621 accgcctcgc accaggtctc gcggaaggtg ttgccttggc gctcgatcag cagcaggcgc
    37681 tgctccgctc cgccaaccgg gatgatcagg cgcccggcgg gggcgagttg ttccttgagc
    37741 gccggcggca ggccgctcgc cgccgcggcg acgatgatgc tgtcgaacgg cgcagcctcg
    37801 ggaagaccga ggctaccgtc ggcaagtttc aaccgtacgt tgggcagacg caaaggccgc
    37861 aggttcgcgc gtgcgcgatc gagcaggccg cggatgcgct cgaccgcgta gacctcggtg
    37921 gcgagcagcg acagcactgc cgcctggtag ccgcagccag cgcccacctc gagcgtgcgt
    37981 ccgagctcgc ggccgctgcg cagcagttcg agcatgcgcg ccaccacgaa gggttgcgag
    38041 atggtctgct ggaagccgat cggcagcggg gtgtcgtcgt aggcgctgaa ggcgagcccc
    38101 tcatccacga aggcgtgacg aggcaccgcc tgcatcgccg cgagcacgcg ctcgtcgcga
    38161 atgccctggg cgcgcagccg ctcgaccatg cgcgcgcgcg cgcgcgaagc ctgcccgggg
    38221 tcggacgaac gcatgttcac cgctgcaacc agtcgaagac cggcgcgatc aggccggtgt
    38281 gggtgaggtc gatctgcagc ggcgtgaccg aaacgaagcc gtttgccacc gcatggaagt
    38341 cggtgccctc gcccgcgtcg gcggcaccac cggcggcgcc cacccagtac acggtctcgc
    38401 cgcgcggcgt ctcgctgcgc accaccggct cggccttgtg gcgcttgccc aggcgggtga
    38461 cgcggatgcc ctgcaggcgc tcgtaagcca cgtcgggcac attgacgttg agcagcaccg
    38521 ggcgcggaaa ggggttgtgc atgaagcgct cggcgagatc acgcgcgacg cgggcggcgg
    38581 cggtgaagtc ggtggccgac ttgctcacca gcgagaccgc gatcgacggc acgccgagca
    38641 ggaagccctc ggtggcggcc gcgaccgtgc ccgagtacac cgtgtcgtcc cccatgttgg
    38701 caccatgatt gacgccggag acgaccatgt cgggcaggtg gtcgagcatc ccggtgacgg
    38761 cgagatggac gcagtcggtc ggggtgccat tgacgtggta aaagccgttg gaggtccggc
    38821 gaagcgagag cggacgatcg agcgtcagcg agttgcttgc gccgctgcgg tcgcgctcgg
    38881 gcgcgaccac ggtgacctca ccgatcgtgc cgagcgcctc ggcaagggct gcgatgcccg
    38941 gggcgaagta accgtcgtcg ttgctgacca ggatgcgcat cttgattccg tgcgggtggc
    39001 tgcgaagagt tgcgagggcc tgaacggggc gccgcgaacc ggcgagagcg gggatattag
    39061 catggcgtac cgggcggcac gccggcgaac ggcgcaaaca aaaaaaccgg cctgggccgg
    39121 ttgatttgat tggtcggggc ggcgggattc gaactcgcga ccccttgcac cccatgcaag
    39181 tgcgctacca ggctgcgcta cgccccgaca caagccgcca ttatagcagc ggtttccaga
    39241 aataccagta tttttgcgag cgacgacttg gcgacgagag cgcctgcggg atcaggcgcg
    39301 caattcctgc agcgtggcgg tgatctcggc gcgcagctcg cgcagcatgg ccttgcactg
    39361 ctcgagctcc acgccgttct cctgctcctg gatcgccgac tcgccgaggc ggttgcgcgc
    39421 accggagatg gtgaagccct cctggtacag caactgacgg atgcgccgga tcagcatgac
    39481 ctcgtggtgc tggtagtagc gccggttgcc gccgcgcttg accggcttca gctgggtgaa
    39541 ctcctgctcc cagtagcgca gcacgtgcgg cttcacgcag cacagctcgc tcacctcgcc
    39601 gatcgtgaaa tagcgtttcg caggaatcgg gggcagctgc tcgccaccgg gttcagggct
    39661 gcttgcttgc atcgctgagt tgctccaccg cggccttcag tttctggctg gcatggaagg
    39721 tgaccacgcg ccgggcggtg atcgggattt cctcgccggt cttggggttt cgacccgggc
    39781 gctgcggctt gtcgcgcaac tggaagttgc cgaagccgga gagcttgacg ctgtcgccgc
    39841 gctccagcgc cgtccggatc tcctcgaaga agccctccac catgtccttg gcttcacgct
    39901 tgttgagccc gacctgctcg aacagcaggt cggcgagctc ggccttggtg agggtcatgt
    39961 caggctcccg cgcctcgcag gcgtgcaccc agcacggttt cggcatgcgc cacgagcaag
    40021 gcgatcgccg catcgacttc ggcgtcttcg agggtgcgtc gagtatcttg catcgatacc
    40081 ttgaaggcaa ggctcttctt gtcggggtcg atccccctgc cctggtagag gtcgaagagc
    40141 gcgatctcgc gcacgatctc cggcgcggcc tcgcgcagca cctcgagcac acgctcgacg
    40201 ggaaggtcgt tgcccaccac cagcgcgagg tcgcgccgca ccgcctgcat gcgcgagatc
    40261 tcggcatagg cgggaaggcg ggccgcgagc gcggcgtcga gcgcgacctc gaacaccacc
    40321 ggcgcgctgc ccagctcgta gcgctgcacc cacaccgggt gcagctcgcc gagcacgccg
    40381 atcatgtggc cgtcgaggcg cacggcagcc gcgcgccccg gatgcagggc gggatgcgag
    40441 agcggggtga actgcagcgc gcgcggcgcg aacaaggcct cgaggtcgcc cttcacatcg
    40501 tagaagtcga cgttgcgcgc gcgctcgccc cactgttcgg gcaccacctg gccggcggcc
    40561 agggcggcga tgttcatcac ctggtggaaa ccgtgcacgg gctcgccgtc ggccttgcgc
    40621 tcgaacacgc gcgccacctc gaacacgcgc acgcggtcga tctggcgctt gcggttggcg
    40681 gcgagtgtgc cgaccaggcc gggaatcagg ctggagcgca tcacgctgag gtggctggcg
    40741 atcgggttgg cgaggcggat cgggttctcg ttggcgcaga agtcgcgctc ccacgcctcc
    40801 tcgacgaagg cgaagttgac cacctcctgg tagccgcgcg cggcgagcag gtggcgcagc
    40861 gcccacaccg ggcggccgtt ctcggtgctc ggcagcatca tcaggctgcc ctgcggggcg
    40921 actgcaggga tgttgtcgta gccgtgcagg cgggcgatct cctcgatcag gtcttcctcg
    40981 atctcgatgt cgaagcgcca cgacggcggc gtgaccagga agtcgtcgcc actgcgatcg
    41041 acctgcagat gcacacggcg cagcaggccg agcatgtcgt cgtcgtcgag cacgatgccg
    41101 agcacacggc gggcacgcgc cggacgcagg cgcacggggg cacgcacggg cagcgcgtcc
    41161 gtcgcgacgg cctcgaccac cgggccggcc tcgccgccgc agagctcgag caccaggcgg
    41221 gtggcacgct cgagcgcacc gcgcgcgagc tcggggtcca cgccgcgctc gaagcggtgc
    41281 gaggcgtccg agccgaagcc gtagccgcgc gcgcggccgg cgatcgcgtc gggggcgaag
    41341 aaggcgctct cgaggaagac ctcggtggtg tcgagggtga tcccgctgtc ctcgccgccc
    41401 atgatgccgg cgagcgcgag cgcgcgcgcc tcgtcggcga tcagcagggt gtcggcggcc
    41461 ggggtcacgg tctgttcgtt gagcagcagc acctgctcgc ccgcgcgcgg caggcggacg
    41521 tggatggcgc cctgcagctt cgtgttgtcg aaggcgtgca gcggctggcc gagctcgagc
    41581 atgacgtagt tggtgatgtc gaccagcgca ctgatcgagc ggatgccact gcgtcccaga
    41641 cggcgcgcca tccagtcggg ggtcgcggca cgagcgtcca cgccgcgcag gatgcggccg
    41701 cagtagcgcg gacaggcctg cggcgcatcc agcacgatgt cgcggcgtgc atcgatcgaa
    41761 ggcgaaacgg gttcgatggc gagcgcacgg aactcgccgc cggtgatcgc cgcgacctcg
    41821 cgcgccacac cggtcaggct caggcagtcg gcacggttgg gggtcagctt gatcgtgaac
    41881 agggtgtcgt ccaggccgag gtaggcgcgg atgtcggtgc ccaccggcgc atcctcgggc
    41941 agcgcgtaga ggccggagtg gtcctcggag aagccgagct cgcgcgccga gcacagcatg
    42001 ccgaaggact cgacgccgcg cagcttggcc ttcttgatct cgaactcgcc gggcagcacc
    42061 gcgccgacca ccgcgcacgg taccttcatg ccggcggcgg cattgggcgc gccgcagacg
    42121 atctgcagca gctcgcccgt gccggcgtcg accttgcaga gcttgagctt gtcggcgttg
    42181 gggtgcttct cggcctcgac gatcctggcc accacgacgc cacggaaggc gggcgcggca
    42241 ggttcggcct cctcgacctc gaggccggcc atggtcagca gatggccgag tccggcgctg
    42301 tccagttgcg gatcgacgaa ggtccgcagc cactgttctg agaattgcat gattcgatta
    42361 cccggattgc gtggtagggc gcagcttgtg cgaagccgct cagcggaact ggccgaggaa
    42421 gcgcaggtcg ccctcgaaga acaggcgcag gtcgttcacg ccgtagcgca gcatggtgag
    42481 gcggtccggc cccatgccga aggcgaagcc ggtgtagcgc tcggggtcga tgccgccgaa
    42541 gcgcagcacg ttggggtgca ccacgccgca gccggcgatc tccagccagc gcccctcgag
    42601 cgcgccgctc atgaaggcga cgtcgatctc ggccgaaggc tcggtgaagg ggaagaagga
    42661 cgggcggaag cgcacctgca ggtcgtcggt ctcgaagaag cggcgcagga agtcggcgat
    42721 cacgcccttg aggtcggcga agctcaccgt ctcgcccacc cacaggccct cgacctgatg
    42781 gaacatcggc gagtgggtgg cgtcggagtc gacgcggaag acccgccccg gcgcgatgat
    42841 gcgcaggtcg ggcatggcgt cggcgtcgcg gtggcgctcg acatgggcct gcatggcgcg
    42901 gatctgcaca gggctggtgt gggtgcgcag caggacgtcg tcgtggcctt cgaggtagaa
    42961 ggtgtcgtgc atcgagcgcg ccgggtgatt ctcgggcgtg ttgagcgcgg tgaagttgtg
    43021 ccagtcggtc tcgatctcgg ggccgtcggc gaccacgaag ccgatcgagc cgaacaggcg
    43081 ctcgacgcgc tcgagggtgc ggctcaccgg gtgcaggccg ccctgcacgc caccacgccc
    43141 gggcagggtg acgtcgagcg cctcggcggc gagctgggcg agcagcgcgg cttcgcgcag
    43201 cgcgttgcgg cggccctcga gtgcggcctc gatcgcggtc ttggcggcgt tgatcgcggc
    43261 acccgcctcg cggcgcgcct cgggctcgag cttgccgagc gccttcaggc gctcggtgag
    43321 cgcgccggcc ttgccgagat agcgtgcctt ggcctgttcg agctgcgcgc cgtcggccgc
    43381 ggcggcgaat tcggcggcgg ccagttgtac cagttgatcg agctgttcca tgtccctgcc
    43441 ctggcggaat gcggtgttgc gggatgagcg ccgcggagcg cgacgctcat cgggaattcg
    43501 gggatccgga cgcggcgccc gccgggcgcc gggaatccag aaaaaaaaag gaggccaggc
    43561 ctcctttttt ttggctgcgc gcgattacgc agcgagtttg gcccgggcct gctcggcaat
    43621 cgcggcaaac gccggcttgt cgaacacggc caggtcggcc agcaccttgc ggtcgatctc
    43681 gatcgcagcc ttcttgaggc cgttcatgaa cacgctgtag gtcaggccca gctcgcgcgc
    43741 ggcggcgttg atacgcgcga tccacagggt gcggaactgg cgcttgcgct gacgacggtc
    43801 gcgataggcg tactgacccg ccttcatcac cgcctgcttg gcgatgcgat agacgttctt
    43861 gcggcggcca cggtaaccct tggcctggga aaggactttc ttgtgacggg cgcgggcggt
    43921 tacaccacgt ttgactcggg gcattgcggt ctcctatcag gcgtacggaa gcatggcgcg
    43981 gatcagcttt tcatctgccg catgcacttc ggtcatgccg cgcaggtgac gcttcacctt
    44041 cgtcgtcttc ttggtcagga tgtggcgctt gaacgcctgg gaccgcttga tcccaccgct
    44101 ggagcggacc ttgaagcgct tcttcgctcc gctcttggtc ttcatcttgg gcattgctga
    44161 gactccatgt ttttggatga caccaggtag cgccgaaaag cccggcgcgt tttgttaccc
    44221 ggcaccactt gttttccgcc ggagggaagc cccctcccgc ggtctcgccc ctcgcggggc
    44281 aatttcttca cgaagaagct cagtgcttct tcttgggcgc gatgatcatg atcatctggc
    44341 gcccttccat cttgggcatc tgctcgacct ggcccagttc ctccaggtcg gccttgacac
    44401 gctcgagctg gcgcaggccg aactcctggt gcgccatctc gcggccacgg aagcgcaggg
    44461 tgaccttgca cttgtcgccc tcttccagga agcgcttgag gttgcgcagc ttgatctggt
    44521 agtcgttctc gtcggtgccg gggcggagct tgacctcctt gacctgcacc tgcttctgct
    44581 tgagtcgggc ttcgtgggcc ttcttctgtt cctgatactt gaacttgccg aaatccatca
    44641 gcttgcacac cggcggcaca gccatcggtg cgatttcgac cagatccagc ccggcttctt
    44701 cggccatgtt gagggctgcg ttcagggaca cgattccgag ctgttcgcct tcttcgccga
    44761 ccagccggag ctcgggcgcg ttgatctccc tatttacgcg ctgcttctta tcttgagcga
    44821 tggttcaact ctccacgaaa accacaaaat cagaccgtgc cggctttcgc ttcaacttcg
    44881 cgacgccagc gttcgatcag cgaatcgagg gacatttggc caagatcctg gccgcctcgg
    44941 gcacgcacgg ccaccaggcc cgctgctttc tccttgtcgc cgatgacgat ctggtagggc
    45001 agcttctgca cgctatgttc gcgaatttta tagttaatct tctcgttgcg caaatccgcc
    45061 tcgacgcgga agcccgcctt cctgagccgt gcagcgacct cggtcgcata gtcggcctgc
    45121 ccttccgaga tgttcatcac caccgcgtgc tgcggcgcga gccacatcgg catcgccccc
    45181 gcgtagtgct cgatcaggat gccggtgaag cgctccagcg aaccgaacag cgcgcggtgc
    45241 agcatcaccg gacgccggcg cgagttgtcc tcggccacat aatggatgtc gaagcgctcg
    45301 ggcaggttca tgtccacctg cagggtgccg cactgccagt cgcggccgat ggtgtcgcgc
    45361 aacacgaact ccagcttggg gccgtagaag gcgccctcgc ccgggaacag ctcgtaggcc
    45421 atgcccatgt gctcgagcgc cgcagcaagc gcgccctcga gcctgtccca ggtctcgtcg
    45481 ctgccgatgc ggttctcggg gcgggtcgac agcttgatgc gcacgttgtc gaagccgaag
    45541 tccttgtaga tgtcgaggat cagcgcgacg acgtccttgc actcctgctc catctgatcc
    45601 tcggtgcaga agatgtgcgc gtcgtcctgg gtgaagtggc gcacgcgcag caacccatgc
    45661 agcgcaccgg acggctcgta gcggtgcacc ttgccgaact cggccatacg cagtggcaga
    45721 tcgcggtagc tcttcaaccc ctgcgcgaac atcgacaccg cacccgggca gttcatcggc
    45781 ttgagggcga agacgcgctc gtcctcggtg accgtggtga acatgttctg gcggtagttc
    45841 tgccagtgac cggacgtctc ccacagcccg cgatccatga cgtcgggcgt attcacctcg
    45901 acgtagccgg cctcttcctg acgttcgcgc atgtagccga tcagggtatt gaaaaggcgc
    45961 catccccggg gatgccagaa caccgcacca ggagcctcgt cctggagatg gaagaagtcg
    46021 agctgcggcc cgagcttgcg gtggtcgcgc ttctcggcct cctcgatcat gtgcaggtag
    46081 gcgtcgagct cgtccttctt cgcccacgcg gtgccataga cacgctgcag catctcgttc
    46141 ttcgagtcgc cgcgccagta ggcgccggcg agcttggtga gcttgaagac cttgagcttg
    46201 ccggtcgagg gcacgtgcgg gccgcggcaa aggtcgatga aatcgccctg gcggtacagc
    46261 gagacgtcct cgcccgccgg gatcgaggcg atgatctcgg ccttgtagtg ctcgccgatg
    46321 cccttgaaga agtccaccgc cttgtcgcgc ggccacacct cgcgatgcac gggaatctcg
    46381 cgcttcgcga tctcgcccat gcgctgctcg atcgcctgca ggtcctcggg ggtgaagggg
    46441 cgcttgtacg agaagtcgta gtagaagccg ttgtcgatca ccggcccgat cgtcacctgg
    46501 gcgtcgggaa agagctcctt caccgcgtgc gcgagcaggt gggcggtgga gtggcggatg
    46561 atttcgaggc cttcggcatt cttgtcggtg acgatggcga gatccgcgtc cgcttcgaag
    46621 cgatgcgaga gatcgaccag cttcccgtcg gtgcgaccgg cgatcgccgc cttggcgaga
    46681 ccggcgccga tcgaggctgc gacctcggca acggtcaccg catgatcgaa gctgcgcacg
    46741 gaaccatcgg ggagcgtgat gttgggcatg actttggcct cggactgttg gcgctccgcg
    46801 aagcgcggaa cgtgcagagg aaatcgggaa aacgtggacg aaaaaaaagc gcggtctagg
    46861 cgcgcttttt cctcttagca gacaagcgga gccgacctgt tcagtttccg gcctgagtgg
    46921 tagttcggaa catgactttt cgactccaga atcctggtag gcgcgattgg attcgaacca
    46981 acgaccccca ccatgtcaag gtggtgctct aaccaactga gctacgcgcc tgctgaagtc
    47041 ccgcattata gacacgacaa agaacttgtc aaagtttttt tgcggttttt tccgtgccgc
    47101 ggaacgcgat cacttcttga ggcgcgtcac cacgaagagg atcaccacgg caccgacgac
    47161 cgcgccgagg aaacccgcgc cctcgttcgc atggtagatg cccagcgcct ggccgccgta
    47221 ggtggcgacc agcgagccgg cgatgccgag cagcgaggtc atgatgatcc cgaggccgtc
    47281 cttgcccggg tgcagcaggc gcgcgacgaa gccgacgatg aggccgatga ggatggttcc
    47341 gatgatgccc atgttgctct cctgtaaggg gatggggatg gagcaggtgc cgcgccgttc
    47401 agccctgcgg ccaggcggcg aggaactgct tccagtgcgg cgcgtcgatg cggccgagcg
    47461 cctcgcgcac cgtctccacc tccgccgccc acgcggcggc gtcgagatgc ccgcgcatgc
    47521 gctcgaagcg caggtagacg aggtaggtgt tgacgacgtc ggtctcgcag tagtcgcgga
    47581 tctcggcgat ccgcccctcc tgccaggcct gccagaccgc cgaaccgtcc atgccgagct
    47641 tgccgggata gcccatgagc ttggcgagat cgtcgagcgg cgcgttggcg cgtggctggt
    47701 acagcgccag caggtccatc aggtcgagat gacggctatg gtagcggctg atgtagttgt
    47761 tccacttgaa gtcgcgcgag tcgtggtagt cgccctcgcc ctggtcccag tagcgcggcg
    47821 ccgccacccc gtgcagcatg ccgcggtagt gcagcaccgg caggtcgaag ccaccgccgt
    47881 tccacgacac gatctgcggc gtgtagcgct cgatgccgtc gaaaaagcgc tggatgatct
    47941 caccctcgcc gctctcgggc tcggacagcg agaacacgcg gaaatgctgc gcatcgcgca
    48001 gcacgcagga gatcgccacc acacgctgca ggtggtgcgg caggaagtcg ttgccgtggc
    48061 tggcgcggcg ctgctggaac gcccactccg caacctcgaa gtcggacaga cccgcgggca
    48121 ggttctcgat cgcgcggatg ccggcgacgt cgggaatggt ttcgatgtcg aagacgagga
    48181 ccggcatcat ttcctcgacc acgaagcgcc ctgctgcacc caccagcccg gctgggcgcg
    48241 gtcgagccag cgctgcgcga aggtgcgccg cacctcgccc tcccactccg gatggccgtt
    48301 ggcacgcgcg atctcgcggt agagcgcggc gcggtcggcg ttctcggccg cgaccgcggc
    48361 gttggcctgc gcgcgctgcg cgagcggcac cgccgcggcg tcgcgcaggc tcaccgtgcc
    48421 gtcggcggcg atccccaccg cgcccgacgc atacagcggc gcgagctgcg catgacgctg
    48481 ctgcatcgcc ttgcgcagcg cggagatcgc cggggtgtcg atctcgaggt tgccctgcgc
    48541 atgcaccgcg aaggcgagtg cgaggccgat gaacacggcc gccacgcgcc ccgtcaggga
    48601 agcggacggc atcgaagggg atttcatttc gtgcctcccg cggccggcgg cgtgacaggc
    48661 gcgctgcccg caccctcgcg cagctgccac acctcgtcga tgatgcggtc ggcggccttc
    48721 tcggccgccg cggccgggaa atagatgttg atcgtgacgc aggccgcggt actcgcaacc
    48781 agcgcagccg cgaacagcca gcgcgcagca gggttcatgc cgtcctcgcg gtacatgcag
    48841 attcaatcga tcgtgggaga gacgtcctcg gccaccacgc gctgcaggcg ggccaccagt
    48901 tcgttccaat ccacgcgccg attgtagccg atgacgtcga gcgccgggat gccgccgccg
    48961 cgcacgatgg tgaagccgcc atcggcgcgc acaccgccgt ccggctccgc atccaggccg
    49021 cccatctcgc ataccccatt ggcaagccgg caacgcaggc cgagctcgcg ataaccgaag
    49081 gtctcgaaca gacgcagcac gctgcgctgc accgccgcga gcgcgccccc gccgccaagc
    49141 gcgctgatgt tctccaccgc gcgctggctg atgcggcggc gctcgtcgcc ggcgatgctg
    49201 gcaatgcggg cgtcgaaggc ggcaggccgc cagttcgaca gctccaggcc gcgcacgtcg
    49261 gcatcgatgt ggccggtgat gctgccgaag ctgaaggtct cggtgagctg ggcgaggtcg
    49321 atgtgacgcg cctcgatctc ggccgtcagg tgcgaggcga cgccgaaggg ttcgcgcacg
    49381 cgcagcccgc tcgcctgcag ccagccgccg aacaccgaca ccgcgagcgt accgtcgagc
    49441 acgagctcgc ccgggccgaa ctgcagaccc ggcaacgcgg ccgacatcac ccccgccatg
    49501 agcggcaggc cgagcgcctc ggagagcagc ggcatcgaca ccggctcgag caccacgccg
    49561 ccgctcccct cccagcccgc ggcggaccag ccgagggcga gatcctgaag caccagcgtg
    49621 ccgtcgagca gcgggatgcg cgcacccgca aggcgcagcc cggccggctc gagcgcggca
    49681 tcgagcgcga aggcgccgag cgcgagcttc tcccagcgcc cgcccccgac ctgcagggcg
    49741 gccgcacccg ggccgcgcga ggaccagcgc acgcgcccat ccaccggacc gagggcgagc
    49801 acttcgacgg gcaccacctc cttgccgtcg tcacccctgg cggatccccc acccagcggc
    49861 ggcgcgaggc cgaaacccgc cccgtgcagt tccacggcga gcgtctccag gcggcccgca
    49921 cgcagctcca cgcgcgcatc cgcccgcccc tcgaagcgca gccgctgcgc actcgccggc
    49981 gccagcagcg gcgccagcca gcgcgggccg atgcgggcaa ggtcggcgcc ggcgagctcg
    50041 atcgagaggg catccggcgt gccggcggcg gtgtcgatca cgccgcgcgc ggatgccgcc
    50101 gcgagcccgt cgagcgccag ctcggcgcgc tcgagctcga tccggcgccc atcgaagcgc
    50161 ccgcgcgcgc gcaatcgcgg gccggcctcg acgagcagag ggtggatgta ggctgcgccg
    50221 gcatcccagt cgagctgcgc cgaccaggac cacaccgcgc ccgtcgagcg cgcctcgagg
    50281 gtgaaatccg cgcccacgcc ctcggccgcg agcaatccgt cggcgcggcc gaagcccccg
    50341 ccggcgagac ggccgcgcag gctcgccgtc gtggcgcccg cgtcggcagg ccggtagtcg
    50401 agctcggcgt cgagcacgcc ggtcgccttg aatccgcgca ggccggcggc caggtcgccg
    50461 agccagggct cgagcaggtc cgcggccgcg gcaggggtga gccggtgcag ccgggcgcgg
    50521 aggcggccat ccgcctcggt gccagcctcg atgcggccgc catcgggcag gcgcagcgcg
    50581 atccgcaccg gacccgcacc gagcgccagg tcgacgtcgg cctcgaaggg cagcctccgc
    50641 ccgccctgct ccatgcgcgc cgcgttgcaa gcgagcccgc cggcgtcgat ccgcagcctt
    50701 ccgcagcgca gcgtgagcgc gcgccactcg cgcgcaccga tgcgcaggcg gccgatgtcg
    50761 acctcgcccc cttgcgcagg cgcatccagg cgcacgcgca gctcgtgtac ggcgaaaccg
    50821 gggccggcga tctcgccgac ccgggcagcg agcacgcgga acacggccgc gcccgccagg
    50881 ggcacggccg tcaccagcat cagcaggacg agcgagcagg ccagcgcgcg gcgactgcgg
    50941 ccgccgcaag gcagctcgaa acccccagcc gaagtctcca cgcggatcga ctcccgcgtc
    51001 cccggctgcg cagccacccg gagagcctca ggccgggaac acgcccgtcg acaggtagcg
    51061 gtcgccgcgg tcgcagacga tggagacgat caccgcgttc tcgacctggg cggcgatgcg
    51121 cagcgcgaca tgcatcgcgc cgccggagga gatgccggcg aagatgccct cctcgcgcgc
    51181 gaggcgccgg gtcatctcct cggcgtcggc ctggctgacg cgctcgaaac gatcgacgcg
    51241 cggacgctcg aagatcttcg gcaggtaggc ctcgggccac ttgcggatgc cggggatgga
    51301 cgagccctct tccggctcgc agccgacgat gcagatgtcg ggattgcgct ccttgaggaa
    51361 gcgcgaggtg cccatgatcg tgccggtggt ccccatcgag ctgacgaagt gggtgatgcg
    51421 gccgtcggtc tgctcccaca gctccggacc cgtgccctcg tagtgcgcca ccgggttgtc
    51481 cgggttggcg aactggtcga ggatgatgcc gcggccctcg tcgcgcattt tctccgcgat
    51541 gtcgcgcgcc atctccatgc cgcccgagct cggcaccagc accagctcgg cgccgaaggc
    51601 gcgcatggtc tggcggcgct ccacgctctg gttctccggc atcaccagga tcatgcggta
    51661 gccgcgcatc gccgcggcca tcgcgagcgc gatgcccgtg ttgccgctgg tggcctcgat
    51721 cagggtgtcg cccggcttga tccggccacg cgcctcggcg cgcatcacca tcgacagcgc
    51781 cgggcggtcc ttgaccgagc cggccgggtt gttgccctcg agcttggcga ggatcacgtt
    51841 gttgcggccg gcgttgatgc gcttgaggcg caccagcggc gtgcggccga cgtagtcttc
    51901 cagcgtcctg aattccattg ttgccctgtg gggtggggtt cttcgggagg gttcgccggg
    51961 aggtggactc ccgaccggcc cgccgggttc gccgcgcttc agggcgtcag gtcgaactct
    52021 tcggtgcgcc gcggtggata ggtctcccag ccgccgcagg ccgggcagcg ccagtggaac
    52081 tggcgcgcct tgaagccgca ggtgttgcag cggtagcgcg cgacacgccg ggtatggcca
    52141 tggatgagct gcttgatcag atcgatgtct gcgcgctgct ctgccggcgc gttcaacgcc
    52201 gccgcctcga gcagcttgtc gaggccgagc agggtcgggt tgcggcgcag ctcctcacgc
    52261 accatctcgt aggccgcctt gggcccttcg cgctcgagct cccagtggaa gagctcgtcg
    52321 agcaggtcga gcgaggcgtg cgccgcgagc caggcgcgca gcagctggtg gccctgcgcc
    52381 acacgcccga gacgaccgca tgcgtccatg acgcgctcgg cgacgagggc gagatagttc
    52441 ggatcctggt tctcgatgcg cttccaggcc tccagcgcct cctcgtcgcg cccctgggcc
    52501 gcgagcagat cgccgagcag caggctcgcg cgcacgcacc gccgattgac ctcgaatgca
    52561 cggtccagat gcacctgcgc gtcgtcgtgg cgcgagttcg ccagcgccga ggcggcgagc
    52621 tcgcagtgga agttggcgac ctcggtgtgc cagatcacgc cttcatggcc gggcagcgcc
    52681 tcggcgacct cgatcgcctt cgcccagtcc ttctcctgct ggtagatctc gagcaggtag
    52741 cgcagcgcga cgtcgttggc gcgcgtcccg cgcaggcgca cgaaggcggc ctcggcacgg
    52801 tcgagcagcc cggccttgag gaagtcctgg ccgagctccc ccagcgcctg caggcggtga
    52861 tcctcgctga tgtcctcgcg gtcgaccagc agctggtgga tgcggatcgc gcgatcggtc
    52921 tcgccacgac ggcggaacag gctgccgagc gcgaagtgca gctcgacggt ctgcggatcg
    52981 atgcgcaccg cctctacgaa ggcgtcgatc gccttgtcgg gctgctcgtt gagcaggaag
    53041 ttgagcccgc tcaggtagga acgcggcagc gcgcgcgact cctgcaccac ctggcggatg
    53101 tcgatgcgcg cggccagcca gccgagcgca aagaacagcg gcagcgcgag cagccaccag
    53161 tattcgattt ccatcgggaa tcagggcatc ggcaggcggg actcggcggc ggcgagcgcg
    53221 gtctcggtcg aggccttctc gcgctcgacg agctcgagct ggcggcgcag gcgcgagatc
    53281 tcacggcgct ggcgcatcat cgaggcgagc gtggcggtga cgccgatcag ggcaccggcg
    53341 gcgaaggtga ccaggatcac gaacaccagc ggaagttgcc actggatgcc gaagaagaag
    53401 ttcagcgtga ccagatggtc gttcttgatc gcgaagccga acaagaggaa gaacagcagc
    53461 aggcggatga tccagatgat tgcacgcatg accggcatga ttcccgaacg atgaacaaaa
    53521 agaaggcgac cgcagtcgcc ctccattatt gcctgtaaac cgatcgccgc gcggtcaact
    53581 tccgccgaga tccacccttt cgcgcaattc cttgcccgcc ttgaaatgcg gaacgtattt
    53641 ttccggcacc aggaccttct cgccggattt gggattgcgc ccggtacggg gcggacggta
    53701 gttcagcgca aagctgccga acccgcggat ctcgatgcga tcaccgcgcg cgagcgcgtc
    53761 ggtcatcgca tcgagaatca tcttgaccgc gtaatcggcg tcctttgcga ccagctgggg
    53821 aaaacgctcc gccagctggg cgatcagctc cgatttggtc atgatcggac agattactgc
    53881 ttctgctcgt tcagcttggc cttgagcagg gcacccaggt tggtggtgcc ggcagacgcg
    53941 gagctctcgg aagccagctt gttcatggct tcggactgct cggcctggtc cttggcgcgg
    54001 atcgacaggc tgatcgagcg ggtcttgcga tccacgttga tcaccagcgc ctcgaccgag
    54061 tcaccttcct tgagcatggt ggtcaggtcg tcgacacggt gcggggccgc ctcggaggcg
    54121 cgcaggtagc cttcgacgtc gtcacccagc gagatcaccg cgccacgcgg ctcgaccgac
    54181 ttcacggtgc cgcgcacgag gctgttcttc tcgtgggtgg cgatgaagtt ggtgtagggg
    54241 tcgccctcga gctgcttgat gccgagcgag atgcgctcgc gctcgacgtc gatcgccagc
    54301 accacggcct cgacctcgtc gcccttcttg aagcggcgca cggcgtcctc gcccgactcg
    54361 ctccacgaca ggtcggaaag gtgaaccagg ccgtcgatgc cgccttccag gccgatgaac
    54421 acgccgaagt cggtgatcga cttgatctgg ccacggacct tgtcgccctt cttgtggttg
    54481 atggcgaaat cgtcccacgg gttggacatg cactgcttca tgcccagcga gatgcggcga
    54541 cggtcttcgt cgatctcgag gatcatgacc tcgacctcgt cgcccagctg cacgaccttg
    54601 gtcgggtgga tgttcttgtt ggtccagtcc atctcggaca cgtggaccag gccctcgatg
    54661 ccctgctcga cctcgacgaa ggcgccgtag tcggtgatgt tggtgacctt gccgaacagg
    54721 cgggtgccct gcgggtaacg acgcgagatg ccgacccacg gatcttcgcc gagctgcttg
    54781 aggccgagcg agacgcggtt cttttcctgg tcgaacttga gcaccttggc ttcgatctcg
    54841 tcaccgaccg acagcacttc ggacgggtga cggacgcggc gccaggccag gtcggtgatg
    54901 tgcagcaggc cgtcgatgcc gccgaggtcc acgaacgcac cgtagtcggt gatgttcttg
    54961 accacgccct tgatgacggt gccttccttg aggttggcga gcagcttctc gcgctcttcg
    55021 cccatcgact cttccagcac ggcacggcgc gaaaccacga cgttgttgcg cttgcggtcg
    55081 agcttgatga ccttgaactc gtattccttg ccttcgtacg gcgtggtgtc cttgaccgga
    55141 cgcatgtcga ccagcgagcc cggcaggaag gcgcggatgc tgttggtcat gacggtcagg
    55201 ccacccttga cgcggccggt gatgacgccc ttgaccaggg tgccgtcgtt gagcgccttc
    55261 tcgaggtcgt tccaggcggc gatgcgcttg gccttgtcac gcgacaggcg ggtctcgccg
    55321 tagccgtctt cgagggcgtc gatggcaacg tggacgaagt cgccgatgtt ggcctcgagt
    55381 tcgccgcggt cgttgcggaa ctcctcgatg ggcacgtagc tttcggactt caggccggcg
    55441 ttgacgacga cgaagttctg gtcgatgcgc acgacttcgg cggtgatgac ttcaccggcg
    55501 cgcatttcct ggagggcgag gctttcctcg aagagggcgg caaagctttc ttcgaaggca
    55561 ggggtggcgt tggacataaa aggtggattc cggcaccgcc gtgggacggc aaacatggct
    55621 ggttcaagaa aaaacgcgcc ggagcccacg ctcccgcgcg attgcgttca accgggcgac
    55681 ttcgccccct gcccgacgag atcgagcacg aaggcgacag cctcgtcgac gttccgttgc
    55741 gtggtgtcga gcagggccgc gtccggcagc ttcacgagcg gcgcaacagg ccgggcggca
    55801 tcgcgcgcat cccgttcctg gaggtccttg agaagacttt ccatgttagc agccaaaccc
    55861 ttttcgatca actgcttata gcggcgttcg gcacgcgcct cggccgaggc ggtgaggaag
    55921 accttgaggc ccgcgtcggg gaagatcacc gagcccatgt cgcgcccttc ggcgaccagg
    55981 cccggcgccg cgcggtagtc gcgctggcgg tcgagcaggg ccgcgcgcac cgccgccagc
    56041 acggcgacct tggaggcgcc gaccgagcag gcctcggagc ggatctcgtc ggtgacgtcg
    56101 cagtccgcgc cctcgccgag cagcacccgc ccgccctcga agcgcgccgg cagggtcgcg
    56161 gcgagcgcgg ccacgccggc ctcatcatcg aaggcgacgc ccgcgcgcat cgcggccagc
    56221 gccaccaggc ggtagagcga gccgctgtcg aggtagtgcc agcccagcgc ctcggcgacg
    56281 cgcgccgcca ccgtgccctt gcccgaggcc gagggaccgt cgatggccag caccggcacc
    56341 ggctgcgcca cccgcgcgaa ggcctcgaaa tagccgggga aggtcttgtt cacgcacttc
    56401 gggtcgttga tgcgcacgcg gcagccgccc aggctcgcca acgagaagca catcgccatg
    56461 cggtggtcgt cgtaggtgtc gatcgcggcc ggctgcaggc gctgcgggcg ctgcaccacc
    56521 aggtagtcgg cgccctcctc cacctcggcg ccgagcttgc gcagctcggt ggccatggcg
    56581 gcgatgcggt cggtctcctt gacccgccag ctcgcgatgt tgcgcagccg gcacgggccg
    56641 tcggcgaaca gcgccgccac cgcgagcgtc atcgccgcgt cggggatgtg gttgaggtcg
    56701 aggtcgaagg ccttcagcac gccgccggcg ggagctgcgg cctcgatcca gttgtcgccc
    56761 agggtgatgc gcgcgccgag ctgctcgagc gcctcggcga agcgcacatc gccctggatg
    56821 ctggaccggc ccacgccctc gacccgcacc ggcccgccgc cgatcgcgcc ggcggcgagg
    56881 aagtaggacg ccgacgaggc atcgccctcg acgaacaccg tgccggggct gcggtagcgc
    56941 gcaccacccg ggaccacgaa gcgctcccag ccctgctggt tcacctgcac cccgaagcgc
    57001 gccatcagct cgagggtgat gcggatgtag ggcttggaga taagctcgcc caccacctcg
    57061 atcgtggtct ccacgccggt gagcggcagc gccatcagca gcgcggtgag gaactgactg
    57121 gagacgtcgc cgcgcacgcg caccacgccg ccgggacgga tggtcgccgg cttgagatgc
    57181 agcgggggat agccctcgtt ggcggtgcag gcgatgtcgg cgccgagctg gcgaagcgca
    57241 tcgacgaggt cgccgatcgg gcgctcgtgc atgcgcggca cgcccgacag gcggtactcg
    57301 ccgcccgaca gcgccagcgc cgcggtgagc ggacggaagg cggtgccggc gttgccgagg
    57361 aagagctcgg cggccttcac cgggaaggga ccgccgacgc cgcgcacgcg gtagtcgagg
    57421 ctgtcgccct cgcgccgcca atcgacaccg agcgcgcgca gggcctcgag catgcgctcg
    57481 acgtcgtccg acagcagcag gtcgcggatg tcggtctcgc cctcggcgag cgcggcgagc
    57541 agcagcacgc ggttggagat gctcttcgag ccaggcaggc ggacgctgcc ggcggcgccc
    57601 agcatcgggg gcagatcgag aaattccatc atgacctcag aaaacggggc ctgccccgcg
    57661 aaacaggaaa aagcgccggc tcactcggcg gtgcggatcg gcagaccctc ggcccaggcg
    57721 ttgcgggcgc gccgggcgcg ctcgaagacc gcctccaggc cgtcgccgtc gccctcgacc
    57781 agcatcatgc gcaggcgggc gagctcgccg aggtaggcgt cgagctcctc gagcagcgcc
    57841 acccggttgg ccacgcagat gtcgcgccac atctcggggt ggctgccggc gatgcgggtg
    57901 aagtcgcgga agccgctcgc cgcgtgcgag aacagcagcg gcgcgttgct gcgcccggca
    57961 aggtcatcga ccaggccgaa ggcgagcagg tgcggaaggt gactcaccgc ggcgaatacg
    58021 cggtcgtgct cctgcggcgt catgccgacg acgttggcgc cgcaggcctc ccaggcgtcg
    58081 cgcaccttct gcacggcctc ggggcggctc tcgggcagcg gcgtcagcac caccttgcgg
    58141 cccatgtaga gctcggcgaa ggccgcctcg accccgctct tctcggcgcc ggcgatcggg
    58201 tgcgccggca ccacgtcggc gagcgcagcg ccgaggtggc tgcgcagcgc ggcgaccacg
    58261 tcgcgcttgg tgctgccggc gtcggtcacc accgtgccgg ggcgcaggtg cggcgccatc
    58321 gcggcgagga tcgcgtccat ctgcccgacc ggcgcggcga gcagcaccag gtcggcgccg
    58381 tcgagcgcat ccgcccagcc ctcggcgatc tcgtcgatga cgccgagcgc gcacgcgcgc
    58441 tcgagcacct cgcgccgccg gccgatgccg acgatgcgct cgaccgcgcc cgcacgccgc
    58501 agcgcgagcg cgaaggagcc gccgatcagg ccgaccccgc agacgaccag cttgccgatg
    58561 tgcgccatcc tccgcccctc gatcaggcga gcgcctggcg cagcgcctcg atgaagcgcg
    58621 cgttctcctc gggcaggccg atcgacacgc gcagccagtg cggcatgcca taggccgcga
    58681 tcgggcgcac gatcacgccc tggcgcagca gcgcctggtt caccccgatc gcgtcgccca
    58741 ccttgaaggt gacgaagttg ccggccgagg ggatccactc caggccgagc tcgcggaagg
    58801 cggcaacgag ctgggccatg ccacggcggt tgacctcggc gctgcgggcg aggaactcgt
    58861 cgtcgtcgag cgccgcctcg gccgcggcca gcgccaccga ggacacgttg aagggctggc
    58921 gcacgcggtt catcaggtcg gccacctcgg ggtgggcgat ggcgtagccc acgcgcaggc
    58981 cggccaggcc gtaggccttg gagaaggtgc gcgacaccag caggttgggg aagcgcgcca
    59041 gccaggcgat cgagtcgtag cgctgctcgg gggcgaggta ttcggtgtag gcctcgtcga
    59101 gcaccaccag cacgtggcgc ggcacctcgg cgaggaaggc ctcgagctcg gcgccgggga
    59161 cgaaggtgcc ggtggggttg ttcgggttgg cgatgaagac cacgcgggtc tgcggctcga
    59221 tcgccgccgc catggcgtcg aggtcgtggc cgaagttctt cgccgccacc tcgatgccgc
    59281 gcgcgccgcg cgcgttggtg gcgagcgggt agaccgcgaa ggcgtggcgc gaatacaccg
    59341 ccgacagccc gggcgcgagg aaggcctgcg aggcgagctc gaggatgtcg ttcgagccgt
    59401 tgccgatcac gagctgcgcg ggttccacgc cgaagcgcgc gcacaaggcc ttcttgagcg
    59461 cgaacgcgcc gccgtcggga tagcgcgaga tctcgccgat cgcggtgatg gcggcgtcgc
    59521 gcgcgcgcac gctcatgccg agcgggttct cgttggaggc gagcttgacg atgctctcct
    59581 cggcgatgcc catctcgcgg gcgagctccg agatcggctt gcccggctgg taggccatga
    59641 tcgcgcggat gtagtcgggg gcaaggctgg caatgctcat gggtcgtctc ctgctgcggc
    59701 ccacgctgtg cgcacgggcc tgttgtgcaa tcggggccgg gctcagatcg ccgcgaccgg
    59761 ataggaaccg atgatcttca cgaaggcggc gcgctcgtcg agttcgcgca gcgcggcggc
    59821 gacctcgggg tcgtcgcgat gaccgttgat gtcggcgtag aacacgtact cccacagccc
    59881 ggaacgcgcc gggcgcgact gcagcttggt catgtccacg ccatggcggg ccatgggctc
    59941 gagcaggctg tggatggccc ccggccggtt gggcgcggag aacaccagcg aggtgcgatc
    60001 cttgcccgaa ggcccggcgt cgtggtcggc gatgaccagg aagcgggtgg tgttgttggg
    60061 gtcgtcctcg atgttgggcg cgaggatgtt gagtccgtag agctgcgccg cggcgtcgcc
    60121 ggcgatggcg caggactccg ggtcctcgga ggccatgcgc gccgcttcgg cgttgctcgc
    60181 caccgggatg cgcggcaggt gcggcaggtt gcggttgagc cactcgtggc attgcgccag
    60241 cgactgcgcg tgcgagtaga cgcgcttggc ggcgccgatg ccctcggcgc gcgacatcag
    60301 ctgctggtgg atgcgcaggc ggacctcgcc gcagaccttg agcgggttgg cgagcagcag
    60361 gtcgagcgtg ccgccgaccg cgccctcggt ggagttctcc accggcacca cgccgtagtc
    60421 ggcgttgccc gcctcgaccg cgcggaacac gtcgtcgatc gccgccatcg ccatgaagtt
    60481 gggcgcggag ccgaagtgct tgcggctggc gctctcggag aaggtgccgg cggggccgag
    60541 gtaggccacg cgcagcggct gctccagccc gaggcaggcc gacatcacct cgcggaagat
    60601 ggtcttcacc gcgtccgcgg acagcgggcc ggggttgagc tcggccaggc ggcgcagcac
    60661 ctgcgcctcg cgctcggggc ggtagtacat caccccgcgc ttgatctcgc cgacgcgctg
    60721 cgcgcagcgt gcgcgctcgg cgaggcgggc gaggatttcc tcgtcgatgc ggtcgatctc
    60781 gttgcgcagt ttcagcagtt cgtcgctcat gctcggcccg tggcccctcc ggcttgcgtc
    60841 ctgatgttgt cccgtatttc cgtgtcgcct cgccctgccc cgcgcgccct cagccgcggc
    60901 gggcggcgaa gtcgcgcagg aagtcgacca gcgcctgcac gcctgcgagc ggcatcgcgt
    60961 tgtagatcga cgcgcgcatg ccgccgaccg acttgtggcc cttcagctgc accagcccgg
    61021 cggccttcga ctcggcgagg aaggcgtcgt tgagggcctc gtccttgaga aagaagggca
    61081 cgttcatgcg cgagcggcag gccggctcga tgcgattctc gtagaaatcg ctggcgtcga
    61141 ggaagtcgta cagcagcttc gccttggcga cgttctgcgc ctcgatcgcg gccacgccac
    61201 cctggcgctt gagccactgg aagaccaggc cggcgatgta gatgccgtag gtgggcggcg
    61261 tgttgtacat cgagccgttg tcggcgaccg ttctgaagtc gaaggcggtg gggcaatgcg
    61321 gcatcgcgtg gccgagcagg tcctcgcgca cgatcacgat ggtgaggccc gccgggccga
    61381 tgttcttctg cgcgccgccg aagatgaggc cgtacttcga gacgtcgatc gcgcgcgaca
    61441 ggatgtgcga ggacatgtcc gccaccaccg gcacctcggc gcggccgatc tgcgcgaggt
    61501 cgggctcgaa ggggtactcg aggccgccga tggtctcgtt cgtgcaggtg aagacatagg
    61561 ccgggtcggc ggaaagcttc cattccgcca tcgccggcac ggtcttgaag ccgcccgcct
    61621 ccgacgacgc ggcgatgttc acctcggcgt acttgcgcgc ctccttctgc gacttctgcg
    61681 accacgagcc ggtgaccacg tagtcggcta cacgcctgtc gcccatcagg ttcatcggga
    61741 tgatcgcgtt ctcggcgatc gccccgccct gcatgaagag gatgcggtag ttcgccggca
    61801 ccgcgagcag ctcgcgcagg tcggcctcgg cctgggcggc gatcgcggtg aactccttgc
    61861 cgcgatggct catctccatg acacccatgc cgctgccgtg ccagtcgagc atctcgtcgg
    61921 cggcctggcg cagcacctcc tcgggcagcg ccgcagggcc ggcgctgaag ttccacacgc
    61981 gactcatcag gcctctccct cttcgccggc tgccggggcc tcgccctcgc ctgccgcagg
    62041 cgcctcgccc gcgtcaccgg cggcttcctc gccacccgcg gcgccctcgc cattggcgcg
    62101 catgctctcg tccgattcgg actcggccac cttctcgatg ctggcgagga aggtgccctc
    62161 gtcgaggttg atcagggtca cgccctgggt cgagcgcccc atctcgcgga tgctctcgac
    62221 gctggtgcgg atcagcacgc caccggtgga gatcagcatg acctcgtcgc cgggctcgac
    62281 cagcaccgcg ccgaccaact tgccgttgcg gtcgctggtc tggatcgcga tcatgccctt
    62341 ggtgccgcgg ccatggcggg tgtactcggc caccggggtg cgcttgccgt agccgttctc
    62401 ggtcgcggtc agcaccgact gcgactcgtc cttggccacc agcatggcga tcaccgcctg
    62461 gccgtcctcc agcgtcatgc cgcgcacgcc gcgcgcgtcg cggcccatcg ggcgcacgtc
    62521 ggtctcggcg aagcgcaccg ccttgccggc atccgagaac agcatcacgt cgcactggcc
    62581 gtcggtgatc gccaccccga tgaggtggtc gccgtcgtcc aggttgaccg cgatgatgcc
    62641 cgccttgcgc gggttggaga acgcgctgag cgcggtcttc ttgaccgtgc cttccgaggt
    62701 cgccatgaac acgaagtgct cctcgtcgaa ctccttgatc ggcagcaccg cggtgatctt
    62761 ctcgccttcc accagcggga agaggttcac gatcggcttg ccgcgcgagt tgcgcgtgcc
    62821 ctcgggcacc tcgtacacct tgagccagta gcagcgcccg cggctggaga agcacagcac
    62881 ggtgtcgtgg gtgttggcga cgaagaggtg gtcgatgaag tcctcgtcct tcatcgaggt
    62941 cgcctgcttg ccacgcccgc cgcgacgctg ggcgcggtag tcggcgagcg gctggcgctt
    63001 gaagtagccg gtgtgcgaca gggtcacgac catgtcttcc ggcgtgatca ggtcctcgat
    63061 gttgatctcg gcggtgttca tcaccagctc ggagcgacgc gggtcgccga actggttgcg
    63121 gatcgcgccg agctcttcga cgatgatcgc ggtgatgcgc tcggggcggg cgaggatgtc
    63181 gagcaggtcg gtgatgaggt ccatcacctc gcggtactcg ccgacgatct tgtcctgctc
    63241 gaggccggtc aggcgctgca ggcgcagctc gaggatggcc tgggcctggg tctcggacag
    63301 gcggtagccc tgggcggaca ggccatattg cgcatccagc ccttccggcc ggtagctgtc
    63361 cgccatcgca cgcgacagca tctcttcgac cagcgccgag cgccactcgc gcgccatcag
    63421 ctcgcgcttg gcgtcggccg gcgtgggcgc ggccttgatc agcgcgatga tctcgtcgac
    63481 gttggacagc gccaccgcca ggccttcgag gacatggccg cggtcgcgtg ccttcttcag
    63541 ctcgaagatc gtgcggcggg tgacgacctc gcggcggtgc tcgaggaagc acaccagcat
    63601 ctgcttgagg ttgagcaggc gcggcttgcc atcgaccagc gccaccatgt tcatgccgaa
    63661 gctgtcctgc aactgggtgt gcttgaacag cttgttgagc acgacctcgg gcatctcgcc
    63721 gcgcttcaac tcgatgacca ggcgcatgcc cgacttgtcg gactcgtcgc ggatctcgct
    63781 gatgccctcg atcttcttct cgttgaccag ctcggccatg cgctcctgca gggtgcgctt
    63841 gttgacctgg tagggcagct cgtcgacgac gatggcctgg cggtcggtct tgccgatcgg
    63901 ctcgaagtgg gtgcgcgcgc gcatgatcac gcggccgcgg ccggtgcggt agccctcgcg
    63961 cacgccggcg aggccgtaga tcaggccagc ggtcgggaag tccggcgcct gcacgatgtc
    64021 gatcagcgcc tcgatgtcgg tgtcgggctc ggcgagcagc ttcaggcagg catcgacgat
    64081 ctcgcccagg ttgtgcggcg ggatgttggt cgccatgccc actgcgatgc cggccgagcc
    64141 gttgatcagc aggttgggga tgcgcgcggg caggaccagc ggctccttct ccgagccgtc
    64201 gtagttcggc ccgaagtcca ccgtctcctt gtcgatgtcg gccagcagct cgtgaccgat
    64261 gcgcgccatg cggatctcgg tgtaccgcat cgccgcggcg ttgtcgccgt cgaccgagcc
    64321 gaagttgccc tggccatcga ccagcatgta gcgcagcgag aagtcctgcg ccatgcgcac
    64381 gatggtgtcg tacaccgcgg tgtcgccgtg cgggtggtat ttaccgatga cgtcgccgac
    64441 gatacgcgcg gacttcttgt aggcgcggtt ccagt
//
LOCUS       DAOTIN010000005        62795 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_437_length_62795_cov_9.215014, whole genome shotgun sequence.
ACCESSION   DAOTIN010000005 DAOTIN010000000
VERSION     DAOTIN010000005.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 62795)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 62795)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62795
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_437_length_62795_cov_9.215014"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(257..796)
                     /locus_tag="P5537_01460"
     CDS             complement(257..796)
                     /locus_tag="P5537_01460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spy/CpxP family protein refolding chaperone"
                     /protein_id="HRV76738.1"
                     /translation="MKNWIKTSIAAAVIATGAIGSTAALAWGGHCDGPRGGKAGWSQM
                     APEQMKAKMAERAELHMARLELALALTPEQKPAFERFKTDMKARAERMAATMAERRAA
                     GQPKTAIERMQRMEEMSKLRQAEMGEARKSVETFYATLSDAQKTVFDAEFQKMGRKGE
                     RGMKGGGPRDGGGMGPGRG"
     gene            993..1775
                     /locus_tag="P5537_01465"
     CDS             993..1775
                     /locus_tag="P5537_01465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV76739.1"
                     /translation="MNTSDHVLIVDDDRDIRQLLADYLEKQGLRCTTAADGREMKAAL
                     ETHRIDLIVLDLMMPGEDGLTLCRNLRASGGPHANTPILMLTARGEDMDRIIGLEMGA
                     DDYLAKPFVPRELFARIRAVLRRTRALPPNLDAAPPANARLLRFAHWCLDTVNRHLVD
                     AEGTVVALSGAEYRMLAVFLSHPQKVLSRDQLMELTQGREADVFDRSIDLLVSRLRQR
                     LGDNAREPAIIKTVRNEGYVLATEVAAEVDTSTAAPGGGGPR"
     gene            1772..3088
                     /locus_tag="P5537_01470"
     CDS             1772..3088
                     /locus_tag="P5537_01470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HRV76740.1"
                     /translation="MRLPLPRSLFARLMLIWLVGIALVLAVSLALFLGERERIGRSAL
                     FEGVAQEIASVADLLDSMSPPERARWIDEIGRRRLRLALRPPHDRLRPLAEDHPLHAA
                     LREAMPQRPATLYTHPRDDRPHPGLAIVLALTDGTPLQVRLPGIPPAPPIMPHQRGPF
                     LAALAALVLGVGLLTWIAVRIATRPLSRMAEAARALGEDPTRAPMDTRGPTEVAQAAA
                     AFNQMQQRVAEHVAERTRILAAISHDLQTPITRLRLRAEMVDDEGLRARIQSDLDGMQ
                     GLVKEGLAYARSLDERSPAQAIELGPLLQALAEDARDMGWTVRVPEDVRGRVVGNPSA
                     LRRALWNLVENGVKFGGEVELTLACGGEQCEIRVRDHGPGLAEDELEKVFEPFYRTEA
                     SRNRETGGTGLGLAITRNLVHAQGGAITLRNHPGGGLEAVLRLRAQ"
     gene            complement(3040..>4083)
                     /locus_tag="P5537_01475"
     CDS             complement(3040..>4083)
                     /locus_tag="P5537_01475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HRV76741.1"
                     /translation="ALLLNHCAALELVEEDGRLCGVVVREAEGGRDYRIAARAVINAT
                     GVWGDALRRRADPAARPLLRPSQGVHVVVDADCLPGGDALLVPRMPDGRVLFMIPWGG
                     KVLIGTTDTPRTDAPDEPEPLAGEVDDLLAAAARWLRRPPAREAVRSVFVGLRPLLGE
                     REGEGGGERGGASSRISREHRVEVSTQGLVSVLGGKWTTYRAMAEEAVDAVEAVGGLA
                     QRSSPTATLALDCGVRPGAEGEGEVGVDASLPGTPPGLPPGLVPGAAAVRRALREDFA
                     LSIEDVLARRSRALFLDAAAAAAVAPAVADIVAHELGWSAPRREAELAAFLALAARYC
                     ARSRSTASSPPPG"
     assembly_gap    4084..4183
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<4184..5490)
                     /gene="glpK"
                     /locus_tag="P5537_01480"
     CDS             complement(<4184..5490)
                     /gene="glpK"
                     /locus_tag="P5537_01480"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HRV76742.1"
                     /translation="MAYLLALDQGTTSSRAIVFDAGGRVRGLAQQAFAQHFPAPDRVE
                     HDPQDILRTQFDCAREALANAGVAARQVAAIGIANQRETTVLWERASGRALAPAIVWQ
                     DRRTAAECERLRAAGWAEDVRVRTGLELDPYFSATKLAWLLDHVPDARARAERGELAF
                     GTIDSWLVWHLSGGRLHVTDPGNAARTLLFNLHSMDWDPVLLERFRIPPALLPRVVAS
                     SGVCGETDPALFGAAIPIAGIGGDQQAATFGQACLAPGMAKNTYGTGCFLLMNTGHAP
                     VASTNRLLATVGWTGVEASPSYALEGSVFMGGAVVQWLRDGLGLVKRASEVEALAASV
                     PDSGGVVLVPAFTGLGAPYWDPHARGTLLGLSRGSGAAHIARAALEAIAEQSADLVEA
                     MARDGAAPLAELRVDGGAAANDLLMQLQADLLGVPVLRPRLLET"
     gene            5614..6486
                     /locus_tag="P5537_01485"
     CDS             5614..6486
                     /locus_tag="P5537_01485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004317054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HRV76743.1"
                     /translation="MPAFWMIVSCFLFACMGVCVKLASGVFSTGEIVFWRGLVSMLMM
                     VGLAASRGIGLRTPHWKMHLSRSVSGSIALGCYFFAIGLLPLATAVTLNYTSPLFVAL
                     VLALFFGERLRGPAVLAILAGFAGVVVLLRPTLQPDQWLGALAGLASGALASLAYVSL
                     RELGRAGEPEVRTVFWFSVMTSAMGLAWALAGELHRPDGLQLATLLGVGLFGGLAQLA
                     MTRSYRYGRTVVSANLSYATVIFASLFGMLLWDEIMPASSWLAVGLIVAGAIGVSLAT
                     PKPSPLPARAAATD"
     gene            6549..6926
                     /locus_tag="P5537_01490"
     CDS             6549..6926
                     /locus_tag="P5537_01490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STAS/SEC14 domain-containing protein"
                     /protein_id="HRV76744.1"
                     /translation="MISTESTERLVSLVVFGEFTLADYKEFEDVVNYRIQFSGPVDLL
                     FDLRQMAGFTLDVAWEEIKFSRQHAGDFRRIAVLTQDQWLTWSAWVSQLFVTAEVKVF
                     DDEDEARAWLAADTAAETAGSAQ"
     gene            6923..7777
                     /locus_tag="P5537_01495"
     CDS             6923..7777
                     /locus_tag="P5537_01495"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004317051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HRV76745.1"
                     /translation="MNASYATLIGAIELAPHLRDADWVVFDCRADLVDPAFGQRAYGS
                     AHLPGAFFIDLETGLSGPKTGRNGRHPLPDPASLAARLAACGVGNHSQVVAYDDAGGM
                     FAARLWWMLRWLGHDRVAVLDGGLQAWMAAGLALDDEPPAARPATYTLALRPDRVDAR
                     YVHEHLGRPDMLLLDARSPDRFRGENEVLDPVGGHIPGARNRFFRDNLDERGCFKQAS
                     VLREEFTSLLGAHTPRQVVHQCGSGVTACVNLLAMESAGLTGSRLYAGSWSEWCADPE
                     LPVARGPA"
     gene            complement(7817..8623)
                     /gene="murI"
                     /locus_tag="P5537_01500"
     CDS             complement(7817..8623)
                     /gene="murI"
                     /locus_tag="P5537_01500"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HRV76746.1"
                     /translation="MSAASRPIGVFDSGVGGLTVVRALMERLPLEDIVYFGDTARVPY
                     GVKSVATIEHFTAQITEFLLQRDVKMLIIACNTMAAVAAEVVHRLAAGIPVLDVIEAG
                     ARAAVAASPGRRIGVIGTPTTINSNAYARRMHELDPAVRVYSQACPLFVPLVEEGWLD
                     HEVTRLTAQEYLRPVLAEEVDSLVLGCTHYPLLKPLLRDVAGPRVRLIDSALTTAELA
                     AERLQQAGLARTGGGVADYRFVVSDVPLRFQTIGERFLGRSLGAVEKVDW"
     gene            complement(8655..9854)
                     /gene="tyrS"
                     /locus_tag="P5537_01505"
     CDS             complement(8655..9854)
                     /gene="tyrS"
                     /locus_tag="P5537_01505"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HRV76747.1"
                     /translation="MSDVQAAIDLIKRGADAVLIEAELVEKLKRGKPLRVKAGFDPTA
                     PDLHLGHTVLINKMRHFQELGHQVQFLIGDFTGMIGDPSGKNSTRPPLSREQILENAK
                     TYQEQVFKILDPEKTEICFNSAWMNDLGAAGMIRLAAQQTVARMLERDDFAKRYGNNQ
                     PIAIHEFLYPLCQGYDSVAMKSDVELGGTDQRFNLLMGRELQKHYGQEPQCVVMVPLL
                     EGLDGVNKMSKSLGNYIGIAEPAKEIFGKTMSVSDTLMWRYYELLSFRSTAEIAQLRA
                     EVEGGRNPRDVKVMLAMEFVARFHGQRAAEEALADFEARFQRNAIPDDIPQVTVNVGA
                     EGLPLFQVLKQAGLTGTTSEAMRMVEQGGVRIDGERAEDKGLLLRAGATVVLQVGKRK
                     FASVVLS"
     gene            9942..11267
                     /locus_tag="P5537_01510"
     CDS             9942..11267
                     /locus_tag="P5537_01510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HRV76748.1"
                     /translation="MKARRTRILADLPARLLSRPRTWIAAGVTGVSIFGVVAATAVAP
                     GSLPADLLVERVVEALPSPAVTRTATDPSLPYVHYERIQPGDTLQAMFNRLRIDDAEA
                     LAHLSGSDAGRKALRQLRAGRSVTAVVSPQGRLLSFALPVGNTGAQVVLERGDAGLAL
                     RESSATEQTMMVEMRSGTITHSLFGATDDAGLPDNVATQLATIFGTWIDFHADLRKGD
                     RFNVVYEAIYEEGNPVRAGRILAAEFINNGERHAVVLYRGPSGKEQYYSDDGKSLQQG
                     FLRSPLEFTRVSSSFGRRLHPIHGSWRDHNGADFSAPTGTPVMATSDATIEFIGTQRG
                     FGNLIVLKHRNDITTHYAHLNGFAKGLAKGQAVSQGDLIGYVGCTGWCTGPHLHYEVR
                     LKDVPADPMTVALPMADSFNDKELAAFKRNTAHLRQRFALLNYELADAR"
     gene            complement(11335..11685)
                     /gene="erpA"
                     /locus_tag="P5537_01515"
     CDS             complement(11335..11685)
                     /gene="erpA"
                     /locus_tag="P5537_01515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014833873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster insertion protein ErpA"
                     /protein_id="HRV76749.1"
                     /translation="MSAEVATPEIMVFTDSAANKVRELIEEEGNPDLKLRVFVSGGGC
                     SGFQYGFTFDEEVNEDDTTFEKNGVMLLVDPMSYQYLVGAEIDYTEGLEGSQFVIRNP
                     NATSTCGCGSSFTV"
     gene            complement(11776..12813)
                     /gene="argC"
                     /locus_tag="P5537_01520"
     CDS             complement(11776..12813)
                     /gene="argC"
                     /locus_tag="P5537_01520"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003942 -
                     N-acetyl-gamma-glutamyl-phosphate reductase activity
                     [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HRV76750.1"
                     /translation="MVKVGIVGGTGYTGVELLRLLARHPGVELGAITSRGEAGMAVSD
                     MFPSLRRRVDLKFVTPQDAALEKCDAVFFATPNGIAMKQAAELVAAGVRVIDLAADFR
                     IRDVAEWQKWYGMEHAAPELVAEAVYGLPEVNREQIRGARVLANPGCYPTAVQLGFLP
                     LVEAGLIDTDHLIADAKSGVSGAGRKAEVHTLLPEAADSFKAYGVPGHRHLPEIRQGL
                     ALAAGRAVGLTFVPHLTPMIRGIHATLYGRLKPGVDAADLQGLYEKRYAGEAFVDVMP
                     AGSHPETRSVRASNLCRIAVHRPQGGDTVVVLSVIDNLVKGAAGQAVQNLNIMFGFDE
                     ETGLDIVPVSP"
     gene            complement(12990..13382)
                     /gene="rpsI"
                     /locus_tag="P5537_01525"
     CDS             complement(12990..13382)
                     /gene="rpsI"
                     /locus_tag="P5537_01525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019447061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HRV76751.1"
                     /translation="MAVTYNYGTGRRKTAVARVFIKPGTGNIVVNGKPVDEFFSRETG
                     RMIVRQPLVLTGNEGRFDIMVNVVGGGESGQAGAVRHGITRALVDYDAGLKGDLRAAG
                     FVTRDAREVERKKVGLRKARRAKQFSKR"
     gene            complement(13395..13823)
                     /gene="rplM"
                     /locus_tag="P5537_01530"
     CDS             complement(13395..13823)
                     /gene="rplM"
                     /locus_tag="P5537_01530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015434700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HRV76752.1"
                     /translation="MKTFSAKPHEVKRDWFVVDGTDKVLGRLASEVARRLRGKHKAIY
                     TPHVDTGDFIVVVNVDKLRVTGNKAQDKKYYRHSGYPGGIYETNFTKLQQRFPERVLE
                     KAVKGMLPKGPLGYAMLKKLKCYAGPSHPHTAQQPQVLEI"
     gene            14452..14871
                     /locus_tag="P5537_01535"
     CDS             14452..14871
                     /locus_tag="P5537_01535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004317038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HRV76753.1"
                     /translation="MECTVKWLDGMSFIAETGTGHIVAMDGAPDAGGRNLAPRPMELL
                     LAGAGGCTAFDVMLILKRGRHDVRGCSVRLEADRAESDPKVFTRIRFIYTITGRKLKR
                     ETVERAVHLSAEKYCSASIMLGKTAEMIHEIELIEAD"
     gene            complement(14927..15547)
                     /gene="coq7"
                     /locus_tag="P5537_01540"
     CDS             complement(14927..15547)
                     /gene="coq7"
                     /locus_tag="P5537_01540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone
                     monooxygenase"
                     /protein_id="HRV76754.1"
                     /translation="MIDQAIIEFDKALRTVFAPARSVRAVPGEDVPDAELGETERSHA
                     AALMRVNHVGEVCAQALYQGQSIMSRDPAIRDTLRQAAQEETEHLAWTERRIAELGGR
                     KSLLNPLWYGGALALGLAAGRFGERWNLGFLAETERQVEQHLKTHLDTLPAADRRSRA
                     IVEQMKVDEAEHAETALRLGAHELPAPAKAAMKLAARVMTTLAYRL"
     gene            complement(15544..16053)
                     /locus_tag="P5537_01545"
     CDS             complement(15544..16053)
                     /locus_tag="P5537_01545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004317034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CNP1-like family protein"
                     /protein_id="HRV76755.1"
                     /translation="MRAGALLLAAVWVPASAGLLLEADPDWKEGEVAMPAAPREAALR
                     MIDIGTPSPNAFFVDEDSVAVGADGVVRYTLVVRARGGAENVSFEGIRCATGERRIYA
                     SGRKDGTWSPLKNSAWQPIVDNGYNRPRAALAHDYFCDGPAGPRDREHALRLLRQKRD
                     LDKPFGVHQ"
     gene            complement(16232..16816)
                     /locus_tag="P5537_01550"
     CDS             complement(16232..16816)
                     /locus_tag="P5537_01550"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004327532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA pyrophosphohydrolase"
                     /protein_id="HRV76756.1"
                     /translation="MLDREGFRPNVGIILVNARNEVFWGKRIREHSWQFPQGGIKHGE
                     SPEQAMYRELHEEVGLRPEHVRILGRTRGWLRYEVPKHWIRREWRNTYRGQKQIWFLL
                     RLVGRDSDVCLRASTHPEFDAWRWSNYWVPLEAVIEFKRQVYQLALIELARILFRSRS
                     FELPDSYRLPEPEPAPEPVRVVIGERGLRDAIRK"
     gene            16984..18732
                     /locus_tag="P5537_01555"
     CDS             16984..18732
                     /locus_tag="P5537_01555"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HRV76757.1"
                     /translation="MRASQFHLFTLKEAPSDAEVVSQKLMLRAGMIRKTAAGIYSYMP
                     MGLRAIRKVEAIIREEMNRAGAMELIMPLVQPAELWQETGRWDKMGAEMLRLKDRHER
                     DFALQPTSEEVVTDIARQELKSYRQLPKNFYQIQTKFRDERRPRFGVMRGREFTMKDA
                     YSFDRSEEAAGRSYDSMFAAYKRIFDRLGLEYRAVAADTGAIGGDRSHEFQVIADTGE
                     DAIVYCPDSDYAANIELAEAVSLLARRAEPAKALEKTPTPGKATCEDVAALLGVPLAT
                     TVKSLVLATDDLDDKGNPAGVTVWLLLVRGDHALNEVKAGKLPGLKAGFRFATEGEIL
                     EHFGCKPGYLGPIGLLKPVKVIADRTVAHMADFICGANDADFHFTGVNWGRDLPEPDL
                     VADLRDVVEGDPSPDGKGMLAIQRGIEVGHVFYLGTKYSKAMNATFLDEDGKPKHFEM
                     GCYGIGVTRILGAAIEQNHDARGIIWPRAIAPFEVVICPVGWGKSQAVRDEAQKLYDA
                     LVATGVDAILDDRDERPGVMFADWELIGVPHRVTIGDRGLKEGVVEYQGRRDAEAAKL
                     PVGEILGHVLARLDQA"
     gene            18750..19415
                     /locus_tag="P5537_01560"
     CDS             18750..19415
                     /locus_tag="P5537_01560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HRV76758.1"
                     /translation="MRRLPAPLRQLAAACALALAAGGAQAGAQQYEPMAASVRAALHA
                     AVSDAVAPTLPIPDAGERAQWLAEMSRRLAKRIPDEAYRKELLTSIHYEATRAGLDPQ
                     MVLGLIQVESAFRKYAISSAGARGYMQVMPFWIKVIGRTDDNLFHMRTNLRYGCTILR
                     HYLDIEKGDLFRALGRYNGSLGKPDYPNLVRAAWERHWSWTPQQLAAAGSARLQAGAA
                     TAR"
     gene            complement(19606..20163)
                     /locus_tag="P5537_01565"
     CDS             complement(19606..20163)
                     /locus_tag="P5537_01565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="HRV76759.1"
                     /translation="MFNKPNLFHGGESSAQRNGQRPAGTNVAAASAAQPAEAAGPSAA
                     REPQAVGREEAPVVAGESRLIVGPEVKLKGAEILDCDTLVVEGRVEATMDSRVLRIAE
                     KGAFKGTVGIDIAEIHGHFEGELTARKQLLIHAGGRVSGKIRYGKILIEEGGELSGDV
                     QSLSAAGKELRAVDDKPRALAAVAG"
     gene            20508..21983
                     /locus_tag="P5537_01570"
     CDS             20508..21983
                     /locus_tag="P5537_01570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HRV76760.1"
                     /translation="MRHLSFRATLLASFLLIAASLAAAVAGGWRGMEAVVHAIQDDKQ
                     RALALSDAARALGERSVELERSARQYEVLGEPTLARRFDAALAEARPALALLESASPA
                     LAREVAAWRVSADHVAAWLASLAAPQPADRAEEDAREDPQSATTTGRIAPPAAEDELR
                     SLGVRAGRLAEALNQHLGDRDRALMGTLEGERRAVTLQILAALVLAGTLAGLAGWWLL
                     RPLGRIEHAIGELGENRLARPIDIGGPADLRRLGARLDWLRLRLTELESDRKRVLRHV
                     SHELKTPLASLREGVALLDDGVLGTLAPGQREVTGILAHSARTLQERIEQLLRLNASQ
                     FDARSLHLQPTALLPLLREVVEEQRLPARARGVTIRLAGEAPIVRADGDKLRTVFSNL
                     LANAIAYSPAGGRVRIELGLAAENVVIDCGDEGPGIEPDELERIFEPFFRGRRSPPAK
                     TGGGSGIGLAIVREFICAHRGSVRALPSDRGAHFRVELPHA"
     gene            21976..22509
                     /locus_tag="P5537_01575"
     CDS             21976..22509
                     /locus_tag="P5537_01575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76761.1"
                     /translation="MPDPELHLAGTAPRNALRALLPATLALLAGCAGVPAWDAGEDTA
                     RAASAEALAHEAAQQRLHTAVQAAQPGQDRLATARRALDSLLADDRTEARVLHPYARA
                     LLEQIRERQQLTLLAERLRRQLDERAHSSAARDQELEALRRQNAELQRKLEAIADIER
                     GLSPPTPPVRPPAGLPE"
     gene            22506..23942
                     /locus_tag="P5537_01580"
     CDS             22506..23942
                     /locus_tag="P5537_01580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HRV76762.1"
                     /translation="MSAPAAFATAGAAPARLLVVDDDVDLLRLLSMRLQASGYHVTTA
                     DGVATARSHLGVERFDLVLSDVRLPDGDGLALFEDIRRQHPALPVILLTAHGSIPDAV
                     EATALGVAGYLTKPFDSQALLRGIRQALQLAGPSHARARAGVHAQAGVAPPAGDTAWR
                     SAIISRSSRMQALLDEARLVAVSDASVLIRGDSGTGKELLARAIHLASPRAAAPFVAI
                     NCGAIPEPLLESELFGHVRGAFTGATSAHQGLVQAAHGGTLFLDEIGDMPPALQVKLL
                     RVLQERAVRPVGATRAQAVDLRTVSATHRDLDAALAAGQFREDLYYRIDVVSLQLPAL
                     AERREDVPLLAEHFLRRLADKYAKRLTGFAPDALETLATAPWPGNVRQLHNVVEQVCA
                     LATTALIPRALVERALRVQPAEALGYAEAKRRFERNYLIQLLKLTAGNVSDAARLAER
                     NRTEFYRLLQRHGLAPELFRGDRPDVEQ"
     gene            23967..24152
                     /locus_tag="P5537_01585"
     CDS             23967..24152
                     /locus_tag="P5537_01585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004338115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76763.1"
                     /translation="MIKRQTIAAMLTTTAIAFSIATPAQAARLLDTAQFDTVAACSGD
                     KPATATPDERKDKPAQT"
     gene            complement(24446..25891)
                     /gene="tldD"
                     /locus_tag="P5537_01590"
     CDS             complement(24446..25891)
                     /gene="tldD"
                     /locus_tag="P5537_01590"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011765029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease TldD"
                     /protein_id="HRV76764.1"
                     /translation="MSKSQNPLKVADRYLLSPYGLGEAELEKTFRKLMRHDIDFADLY
                     FQYQRSEAWSLEEGIVKSGSFDIEQGVGVRAISGEKTAFAYSDDISLDALVGAATATR
                     AIAAAGERRRIGIVPHKLKTRLYRADDPLDSLDDTAKVKLLERLESFARAEDPRVTQV
                     MAHIAGSWEVVMVVRSDGHQAADVRPLVRVSITVIMEEDGRREQGSAGGGGRYDYGWF
                     CDDRLHDYARQAVHQARVNLGADPAPAGTMPVVLGPGWPGILLHEAIGHGLEGDFNRK
                     GSSAFSGRIGQQVAARGVTVVDDGTLPDRRGSLSIDDEGNPTERTVLIEDGILTGYMQ
                     DMMNARLMGMPVTGNGRRESFAHLPLPRMTNTYMLDGDKDPEEIIKSVRKGLYAVNFG
                     GGQVDITSGKFVFSTAEAYLIENGKVTRPVKGATLIGNGPDALTKIRMIGNDMRLDPG
                     VGTCGKDGQSVPVGVGQPTLRIDGLTVGGTA"
     gene            complement(26023..26847)
                     /locus_tag="P5537_01595"
     CDS             complement(26023..26847)
                     /locus_tag="P5537_01595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HRV76765.1"
                     /translation="MTETSLPAPVRIAAIQTVSGPEVAANLEIAARLIAEAAAAGARL
                     VALPEYFPLISKDEAAKVRIREPEGAGPLQEFLAAEARRHGVWLIGGTVPLVAEADDK
                     VRNSTLVYDDQGRRVARYDKIHLFGFQRGEERYDEAATIEPGSTVACFDSPAGRTGLS
                     VCYDLRFPELFRAMGEVDLIVLPAAFTWTTGRAHWEVLLRARAIENQCYLMAPAQGGR
                     HESGRVTWGHTMIIDPWGEILACCDEGPGVVVADVDPARLAAVRESLPALRHRCLA"
     gene            complement(26941..30795)
                     /locus_tag="P5537_01600"
     CDS             complement(26941..30795)
                     /locus_tag="P5537_01600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004338112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdP family protein"
                     /protein_id="HRV76766.1"
                     /translation="MLLLVWCVLAAGVLVLRHVVLPAVGDFRAPIAGLLGERLGVAVA
                     IERIEGGWAGWRPRLRLTGVSLADVHGRKTLTLPEVDATLAWSSLAMLEPHFHRLEIR
                     APDLLVRRDAAGGLHVAGIELAPGDAPGDGGLGWLLAQRQIRIHGARLAWADEARGAV
                     PLELEEVEFRLDRRARPARFALEARLPPGLGERVSVRGELRRIDPLQPQRFAGRLYLE
                     IGRAPLGNWRPWVDLPFGLEGEGTLRAWVDADGRDGHALSADLALDGARARFGEALPA
                     LELARLDGRIELVRKEHELRFAGRGLALATAQGVELAPTDVEVVLEQGEGRDRGRAER
                     TDEGGPELTGGRLVADRLELATVAALAAHLPLDAALRTRLAALAPHGRVEDLRLTWQG
                     EPTAPARWTLAARFDELGLAAGEGLPGLAGLSGSVDGDQDSGRFRIDGEALRLDLPEV
                     FDPGPLSFARLSARGGWQRQEERLAIVLDEAAFENADAAGTAAGRYWPAATGAGEIDL
                     QARLARADATAVWRYLPRVVNEDTRNWLRSGIRAAKVPDARLELKGALDDFPFRDGKG
                     RFLVSVQVADATLDYAPGWPGIEGIDGEVRFEGPGLRIVAPRGRIFGVELVDVLAEVP
                     DLDQRPSEIMTITGRARGPTAEFLRFVSASPVSRRIDGFTDGMVAEGRGELELELVMP
                     LRSTIDSRVQGEYRFTDNRLTLLEALPPLEAARGRLRFTADTLSISEAQARLFGNPLR
                     LSAQTGEDGAVRFRAAGRADAAALAAAWDLPLLDELAGTAEWSADIRVGRRGTRVEVA
                     SDLAGFACSLPQPFGKSAGERWPAQLVIERASGGSGASIGLTVGDRLRAELVQPDGTG
                     LHGGVALGRASADAPPASATGVRVAAVLDRLDLDDWRAVLERVAPAVDSGAGGGVATG
                     GSLAAVAEFALAADELGVFGQTFKAVDLRARADPGGWKARLESDRADGEFDWRAAGKG
                     TLAARFRHLRLVREAGNGQALGDGEPAAEEAPPEDPPQRLPALDVVAERFEINELDLG
                     RLEVFARNRGSLWQLDRFALENADGRLAGRGQWRAGIRQRTELDFSLETAAMGALIHR
                     LGYPDVVRGGAASLAGQLAWRGAPTRIDYPSLSGRLRLETGAGQFNKLEPGVGRLLGI
                     LSLQSLPRRITLDFRDVFSEGFAFDRISGSIDLARGVLRSEDLEIRGPAARIAMSGSA
                     DVVSETQDLRVLVQPTLAESVAIGAAAGLVNPVAGVVTYLAQKLLSDPIEKLFAFEYA
                     VTGAWSDPQVAKRGAAAAAESR"
     gene            31051..33759
                     /gene="glnE"
                     /locus_tag="P5537_01605"
     CDS             31051..33759
                     /gene="glnE"
                     /locus_tag="P5537_01605"
                     /EC_number="2.7.7.42"
                     /EC_number="2.7.7.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008882 - [glutamate-ammonia-ligase]
                     adenylyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional [glutamate--ammonia
                     ligase]-adenylyl-L-tyrosine
                     phosphorylase/[glutamate--ammonia-ligase]
                     adenylyltransferase"
                     /protein_id="HRV76767.1"
                     /translation="MSAPNSVPAPALPPAVAQARRLSRYLSRMLDSQPWLAEALAASI
                     ERPLAEADLQRFVAAREVLHGGGDGALRPALRQLRIWTLCHLIVRDLALAAPLAEITE
                     TMTVLAEVALRHAHDVLRGALVERYGQPLSPTGWEQELLVVGMGKLGGRELNVSSDID
                     LIFIYPEDGDTGGRKSISNYEFFERLGKQLIQALAEITEHGQVFRVDMRLRPNGDSGP
                     LVCCFDMLENYFVTQGREWERYAWIKARVMLGERWPELEQLARPFVFRKYLDFGAINA
                     MRELHAQIRREVARRERANNVKLGPGGIREIEFIAQVFQLIRGGRDTALQVRPTLKVL
                     ALLPERGILSEEAVTELSDAYVFLRRLEHRLQYLDDAQTHDLPEKDADRALIAEAMGF
                     ADYAALLAVLDAHREVVSRHFDSVFGDPSEEDHSLDATWANARDTEAATNALGELGYR
                     HPRAAAERLAAMHASPRYRQLPNNIKSRFDALMPRVLEAAAGTPGADETLARMLDLVD
                     AIGRRGAYLALLQQYPQALRRVADLMSASRWGAQFLTRHPILLDEMLDARSLDNAPDW
                     KTFRVSLSEELEALEPDMERQMDMMRERHHAQVFRLLTQDLAGLLTVEKLADHLSELA
                     DLVLDLTLPLCWRRIKIRHCEEPRFAVISYGKLGGKELGYASDLDIVFLYDDEALEAP
                     EVYTRLAQRVSTWLSSQTAAGQLFETDLRLRPNGESGLLVSSLESFRSYQRESAWVWE
                     HQALTRARFSAGDRAIGEAFERIRSEVLCMRRDLDSLRAEVLAMRHKMRDAHGSKSEE
                     VFDLKHDTGGLIDVEFLIQYLVLGHSHDHPRLTGNLGNIALLRIAGKLGLIPAELAAA
                     CADSYRELRRLQHRQRLNERPSRVDPAEAAAAREPVRALWRAVFGE"
     gene            34411..35940
                     /locus_tag="P5537_01610"
     CDS             34411..35940
                     /locus_tag="P5537_01610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAD domain-containing protein"
                     /protein_id="HRV76768.1"
                     /translation="MSHEIELKLALPKRALPALRRHPLVAAAEKCGNALTLDNTYFDT
                     PKLQLKARKVAVRTRRQGRQMLQTVKCAAVSSGGLSQRPEWETAWTGDFDFSPVDDPA
                     TARLLERHRDELVPVFTTRFRRETRRLVPQEGVSILLMIDTGAVHVRTPEGVEREAEI
                     CELELELESGRAQDLLDLACALAQDLPLMPADLSKAERGYRLFLDTPAGALRAEASTL
                     EPGHNVVEAFRTLALSCVRQWQGNAATALAQGDPDAIDPDNIHQLRVAHRRLRALLKI
                     FAPALPETFAGTWNARLRDNANRFGDARDLDVFHAELLEPVTPEGLADAASMAALLET
                     VRAARAAARHHAGVSLDLATQGRLLLEFTAALHRLRADSLAEAADLRSFARLRLDRLR
                     KRARRGAQAAASLEPTRLHALRIDFKLLRYGVEFFAPLFGAKGIARYLDGLVRAQTTL
                     GFLQDVDSALQRLAEWSRTQPEVAPAAAFVLGWHAPRYARLRRRVLRESEPLLWGDKP
                     W"
     gene            36036..36488
                     /locus_tag="P5537_01615"
     CDS             36036..36488
                     /locus_tag="P5537_01615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HRV76769.1"
                     /translation="MDLLLWRHAEAVDGSPDHTRELTPRGLKQARRMARWLEDNRPKN
                     LKVLVSPTLRTRQTATAFTDEFEIVSSLGPEGNVADILAATGWPEGNGAALVVGHQPA
                     LGRLCALLLSGSEADWTIKKGALWWFTNRVREGETQTVLRAVIPSELA"
     gene            36709..37275
                     /locus_tag="P5537_01620"
     CDS             36709..37275
                     /locus_tag="P5537_01620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004375305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2062 domain-containing protein"
                     /protein_id="HRV76770.1"
                     /translation="MFERFLPTREAITQSRMLRWLGPRLHDPLLWHVNRRSVARGVAM
                     GVFFGLMIPIAQIPAAAIASLLLRGNLLIAAISTLVSNPLTYGPLYYFAYQLGAGVIG
                     TRTPIDLTPADVEAPVRAIDSLAQAWTWVSGIGQPLLVGMVIMAVTGSIIAYWGTQLF
                     WRLRVAARRRRQRRERSARASTRAIGSA"
     gene            37327..38277
                     /locus_tag="P5537_01625"
     CDS             37327..38277
                     /locus_tag="P5537_01625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004375303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76771.1"
                     /translation="MEDSIPDGTVAIIDGVRRIHYDGYWLKAYEPPADTLDAKKRLIQ
                     ALTRRLFNHVEHGINIPGKRLDDARRAYEAEDDPARKRVKGAMYAGALFNRATDIFTK
                     LVELQELGIEIATDNPLMRECGGCLQEALKLGRLVLHRSGDEGIDELWGEPFRAFSIP
                     VEAFYESRYIKIAQALREVDRIAAVMAATFATTPLFRGVEPLVFDFARIAKIKCETLR
                     TDPDIFDVWAEFVTASERLAALSPALGPGADECTRQLAADGLHLILQGRNLVTDIIRA
                     RVTMPKSAREFIERCETFAARAQAASHPPLAAADLGATRA"
     gene            complement(38330..39433)
                     /gene="mnmA"
                     /locus_tag="P5537_01630"
     CDS             complement(38330..39433)
                     /gene="mnmA"
                     /locus_tag="P5537_01630"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004375301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HRV76772.1"
                     /translation="MKVVVGMSGGVDSAVTALLLKRQGYQVTGLFMKNWEDDDDSEYC
                     STRQDLVDVASVCDVIGIDLEVVNFSAEYKDRVFADFLREYEAGRTPNPDVLCNSEIK
                     FRCFLDHAMQLGAERIATGHYAQVRPWTNDGRTEYQLLKAEDGTKDQSYFLYRLTQEQ
                     LAKTMFPLGTLYKREVRRIAAEAGLHVAEKKDSTGICFIGERPFREFLMRYLPTRPGE
                     IRALDDGRVLGEHQGLMYHTIGQRKGLHIGGLKGNQDEAGEHDAWYVAGKDVKANVLY
                     VVQGHAHPALLKDRLVAGDLNWIAGRDPHTNWVYTAKPRYRTPDQPCEIDRIAEGRAE
                     IAFAQPQWAVTPGQSVVVYESKVCLGGGIILQA"
     gene            complement(39462..40157)
                     /locus_tag="P5537_01635"
     CDS             complement(39462..40157)
                     /locus_tag="P5537_01635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76773.1"
                     /translation="MSARLPCLLLSALLALPAATWATAGPEGADGGARLSICYNYGCA
                     SEGSVHVRGPTLRRIGERLAAARNAAEERERLAGAVGGLYRVAATQTAVAADRAGNLL
                     DGGADGRMDCIDHSTSTTRLLQLLEARGALRFHRVVEPARRTRLILQHFSAVIEVLSV
                     AERIDRLPPGQALAGCNCTEDGLVIGGIGEADGDDRPGQRYVVDSWFVDNGEPAVVLP
                     LAEWLNGGGPNVQ"
     gene            complement(40163..40615)
                     /locus_tag="P5537_01640"
     CDS             complement(40163..40615)
                     /locus_tag="P5537_01640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HRV76774.1"
                     /translation="MKDRPWKPNVTVAAVIERDGRFLLVEEETPEGLCFNQPAGHLEE
                     GESLLQATVREVLEETAHHFEPEYLVGIYQWTRPQGDITYLRFAYGGRLRGEEPGRRL
                     DEGIVRAVWLTLDEVRACADRHRSPLILQCIEDWIAGQRHPLALVHHC"
     gene            40839..41759
                     /locus_tag="P5537_01645"
     CDS             40839..41759
                     /locus_tag="P5537_01645"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015434674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transaminase"
                     /protein_id="HRV76775.1"
                     /translation="MSMADRDGFIWQDGKLVPWREATTHVLTHSLHYGLAVFEGVRAY
                     NTVSGTAIFRLAEHTQRLINSGKIYMMDIPYSRDELMEAQKEVVRANKLESCYLRPIA
                     FYGSEKMGISTIGATVHVAIAAWPWGAYLGEEGLQKGIRVKTSSFTRHHVNSTMPRAK
                     LAATYPNSILANLEVTRMGYDEALLLDNQGFVAEGAGENLFIVKDGRIYEPEIASALT
                     GITRDSIHVIARELGYEIGTKRLTRDDIYLADEAFFTGTAAEVTPIRELDDRKIGEGK
                     RGPITEKIQGRFFDVVNGRAPEYAHWLAHV"
     gene            41784..41984
                     /locus_tag="P5537_01650"
     CDS             41784..41984
                     /locus_tag="P5537_01650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-finger domain-containing protein"
                     /protein_id="HRV76776.1"
                     /translation="MVENTDKTQAVVTTAKDLPLHCPPPGAPLWARHPRVFLDILKTG
                     EAVCPYCSAHYVFNGERPKGHH"
     gene            42088..42516
                     /locus_tag="P5537_01655"
     CDS             42088..42516
                     /locus_tag="P5537_01655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004375290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HRV76777.1"
                     /translation="MSRPVFTTALEAEAAFYRALAEGDFEALMAVWSEDEEVVCVQPG
                     GPRIVGLPAVREIWRQILADGARIRIDVNHAVASSTAMMAMHCVLERLATDGPTPRTA
                     TIAATNVFVRGADGWRMVLHHASPVPEMSGPEDSTPRVLH"
     gene            42540..43937
                     /locus_tag="P5537_01660"
     CDS             42540..43937
                     /locus_tag="P5537_01660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HRV76778.1"
                     /translation="MRHTLPAAELFKAYDIRGIVDTVLTPAAVRAIGHAVGSEAVARG
                     QRAIAVGRDGRLSSPALAGALTEGIRAAGIDVIDLGCVPTPLTYFAAFELGCGSCVSV
                     TGSHNPPGYNGLKIVLGGHTLHGEAIQDLRRRIAADDLVDGAGALRSADVRAAYLDRI
                     VGDVRLARPLKIVLDCGNGVAGAIAPELFRRLGCELVELFCEVDGRFPNHHPDPSRPE
                     NLRDVIRALRETDAELGLAFDGDGDRLGVVCKDGEIIHPDRQLMLFAADVLSRVPGGE
                     ILYDVKCTRRLAPWVRAHGGRPTMWKTGHALLKARLQETGAALAGEMSGHMFFQERWY
                     GFDDGLYAGARLLEILSARADANTVLKALPDSTSTPELNLEMREGEPFELVRRLREAA
                     LASPSCFADAREVITLDGLRVEFAHGFGLARASNTTPMVVLRFEADDAAALAEIEAAF
                     RRALDAAWPGLALPF"
     gene            44119..44997
                     /locus_tag="P5537_01665"
     CDS             44119..44997
                     /locus_tag="P5537_01665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDOD domain-containing protein"
                     /protein_id="HRV76779.1"
                     /translation="MTARERREARARDSKQAHKGIDIPSCPGILAQLMDELRQPQVSG
                     KRIAALIGQDVGLAAVVVRSANSPYFGSGRRIASIDDAIRMLGFGMLANLVHEALLRS
                     SIADPGAALERFWDSSRCTAQASAMLARRTGIARPETAYTFGLFHDCGIPLLVKRFPD
                     YKRILGTANQATGRWFTDVEDEALDTNHATIGYLLARSWGLTDAVCTGILCHHDYSVF
                     SPDSGLEVEAQTLIALNLVAEHVAGTHLRTRRDAEWDKGREAVARYLGYAPTELDDLA
                     DDLLYALDRQGEDLPA"
     gene            complement(45038..47278)
                     /locus_tag="P5537_01670"
     CDS             complement(45038..47278)
                     /locus_tag="P5537_01670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HRV76780.1"
                     /translation="MSTLLSNLNPEQLQAVSLPAQHALILAGAGSGKTRVLTTRIAWL
                     IQSGQVDPAGILAVTFTNKAAKEMLARLGAMLPVSTRGMWIGTFHGLSNRLLRAHHRD
                     AGLPQLFQILDSADQLAAIKRLLKTLNVDDEKFPPRELQHFINGQKEAGHRPHAVEAW
                     DDYTRLRVQLYQEYEAQCQRESVVDFAELLLRSYELLERNEPLRRHYQRRFRHILVDE
                     FQDTNRLQYRWLKLFADEGREGGAAMFCVGDDDQSIYRFRGAEVGNMRDFEREFRVSN
                     VIRLEQNYRSHANILDAANAIILHNSNRLGKNLWTDQGAGEPIRVFEAYADADEARWI
                     VEEIQALVRDGGLRSEIALLYRSNAQSRVLEHQLFAAGIPYRVYGGLRFFERQEIKHA
                     LAYLRLIANPDDDTSFARVVNFPTRGIGARSLEVLTDAARTYNTSLYATVPHLSGKPG
                     SALAVFVRLVEDLRRDTAGLPLPELVDHVLDLSGLRAHYKADREGRERLENLDELINA
                     AANFLAEAQAQSGAGEALAQPHALLADFLAHASLEAGDHQADQGADAVQLMTVHAAKG
                     LEFDVVFLSGLEEGLFPHENSILEQDGLEEERRLMYVAVTRARARLYLSFAQSRMLHG
                     QTRYNLRSRFLEEVPAGLTKWLTPPSPRAAAGGAMGGMGGGYFKPSAKSAVGGTPQVP
                     RAPRPSFATLPGGLRIGQAVAHAKFGQGVIVAAEGSGSDAKVQINFGPAGVKWLLLGV
                     ARLEPV"
     gene            47619..47948
                     /locus_tag="P5537_01675"
     CDS             47619..47948
                     /locus_tag="P5537_01675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76781.1"
                     /translation="MKTPKLLPWYARKAGVSIERAETLWRKAVREATAETGWVGNAEY
                     WGAAMDHFVRLLDEERSTLCAPRVQSYVRSQNRMWRLPLIAMEDLFSAFHASWQRQHG
                     ADHRRAA"
     gene            48219..50846
                     /gene="leuS"
                     /locus_tag="P5537_01680"
     CDS             48219..50846
                     /gene="leuS"
                     /locus_tag="P5537_01680"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HRV76782.1"
                     /translation="MQEKYQPAALETAAQQHWDSTDAFRVTEDAGRPKYYCLSMFPYP
                     SGKLHMGHVRNYTIGDVLARFHRMKGFNVLQPMGWDAFGMPAENAAIQNNVPPAKWTY
                     ANIDYMKAQLKRLGFAIDWSRELATCTPEYYRWEQWLFTRLFEKGLIYKRLGTVNWDP
                     VDETVLANEQVIDGRGWRSGALVEKREIPMYYMKITAYADELLSALDELPNWPEQVKL
                     MQKNWIGRSEGVEISFPFDVSSIGHEGVLKVFTTRADTLMGATYVAVAAEHPLATQAA
                     ADNPALAEFIEECKRGGVAEADLATMEKKGMPTGLKVRHPLSDEPLEVWVANYVLMGY
                     GEGAVMAVPAHDERDFAFATRYALPIRMVVGSDAYADTVAPWQDAYADYGRLVNSGKY
                     DGLDFQGAVDAIAGDLAAKGLGAKRVQYRLRDWGISRQRYWGCPIPMIHCADCGDVPV
                     PDEQLPVVLPENVEITGRGSPLAKMPEFYECSCPKCGKPAKRETDTMDTFVESSWYFL
                     RYACAGSTTAMVDERVNYWAPVDQYIGGIEHAILHLLYSRFFTRAMRDCGLVDVSEPF
                     SALLTQGMVVAETYYRELDGGKKQWINPADVVVERDERGRIVAAKLASDGLPVVIGGI
                     EKMSKSKNNGVDPQSLVDQYGADTARLFMMFAAPPDQQLEWSDSGVEGASRFLRRVWN
                     YGHAFATATRAALPAERKLAAGTLPAAAADVRREVHTHLKQASYDFGKHQFNTVVSAA
                     MKILNALEKAHKDLAGVEPAAHAEVAEEGFSILLRLLSPITPHICHALWQDCGFGSDI
                     LAAQWPQVAEDALKQDEIELMVQVNGKLRGSIKVAADAAKADIEAIALASEAAQKFME
                     GKPAKKVVVVPGRLVNIVA"
     gene            50858..51382
                     /gene="lptE"
                     /locus_tag="P5537_01685"
     CDS             50858..51382
                     /gene="lptE"
                     /locus_tag="P5537_01685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_process: GO:0043165 - Gram-negative-bacterium-type cell
                     outer membrane assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly lipoprotein LptE"
                     /protein_id="HRV76783.1"
                     /translation="MTAPGPAATGRRRLLGSALAATVALLSGCGFHLRGPQALDFATV
                     HINVPEQSEFGAQLRRLIATTGTTRVEEDAARAEARLQILANDRGREILSLTGAGKVR
                     EYQLVQALRFQLLDRAGKALIPPTSLSARREYTFDDSQVLGKEQEEALLYRDMQNDLV
                     QQLMRRLGAARRGG"
     gene            51403..52413
                     /gene="holA"
                     /locus_tag="P5537_01690"
     CDS             51403..52413
                     /gene="holA"
                     /locus_tag="P5537_01690"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HRV76784.1"
                     /translation="MNLRPDQLAAQLERPLAPLWLLHGNEPLLVLEAADAIRAAARRQ
                     GFEERETLVVGHGFKWDALTLAAGNLSLFGGAKLIDLRIPTGKPGRDGGDALQRYIAH
                     LPSQTLTLVTLPEVDWATRKTAWFKALADAATTLELNAPERERLPDWVARRLAVQKQS
                     APPEALAFIADHVEGNLLAAHQEILKLGLLHGEGALTLEQVQDAVLDVARYDIDKLRQ
                     AVVEGDPARCARLLEGLEGEGAAPPLVLWALAHETRSLATLCAGRDAGQPLATLFKAE
                     RIFDPRRQQAMTRALGRLGQGHLRAALMHAARIDRMIKGLASGDLWDEFLQLALRLAR
                     RG"
     gene            52534..53811
                     /locus_tag="P5537_01695"
     CDS             52534..53811
                     /locus_tag="P5537_01695"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HRV76785.1"
                     /translation="MDIQHYMQTLGRQARAASRVLAAASTAAKNAALTAMAAEIRVRR
                     AELLAANARDVEEARAAGLEPALIDRLTLDEKGVEAMAAGLEQVAALPDPVGEMSDIK
                     RRPSGIALGKMRVPLGVIGIIYEARPNVTADAAALCLKSGNAAILRGGKEAINANRAI
                     AACVRAGLVAAGLPEHAVQVVETTDREAVGALITMPEYVDVIVPRGGKGLIERISKDA
                     RVPVIKHLDGNCHVYIDDEADPAKVVPIVENAKTQRYGTCNTAESLLVARDVADIYLP
                     EIARMLAGKGVEMRCCAESLALLREAGIAGAKLVEATEADWHEEYLAPILAVKIVAGL
                     DEAIEHINGFSSGHTEAIVTENYSHAMRFLREVDSSSVMINASTRFADGFEYGLGAEI
                     GISTDKIHARGPVGLEGLTSQKWIVFGNGEVRR"
     gene            53846..54430
                     /locus_tag="P5537_01700"
     CDS             53846..54430
                     /locus_tag="P5537_01700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016872 - intramolecular lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chalcone isomerase family protein"
                     /protein_id="HRV76786.1"
                     /translation="MSIRILRSLIAAALLSAGLAQAAITVGNVDFATRQTVQQRALEL
                     NGAGLRTRLGFKVYAMGLYLRAPLSEAGAILADKGEKRIRIVPIRDLEAKQFGDALQA
                     GLEKNHDAAALAALKPATDALLAALAAVGEVKAGTEIVLDRLGSGATRLLVDAKQHGE
                     DIADVALYPALLRIWLGERPADSDLREALLKKPQ"
     gene            54445..54933
                     /locus_tag="P5537_01705"
     CDS             54445..54933
                     /locus_tag="P5537_01705"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HRV76787.1"
                     /translation="MPAGGADMSTFDAIIALPFGPFGIRARDGHVRELVFLPPGTPLH
                     DPRNATAGAAAHALRAWIEAPDEPFPVPLAPCGTPFRRRVWAAIAAIPRGRTATYGEL
                     ATSLGSAPRAVGQACGANPFPLIVPCHRVTSAAGLGGFANAREGWLLEVKRWLLAFEG
                     AL"
     gene            54930..55859
                     /gene="xerD"
                     /locus_tag="P5537_01710"
     CDS             54930..55859
                     /gene="xerD"
                     /locus_tag="P5537_01710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HRV76788.1"
                     /translation="MSGRAPAREAGLQPAHRAELDRFTDALWLEHGLATNTLAGYRSD
                     LARFAAWLETRTQRLPAVSGADLSAYLAEFSRATKPASQRRLIAAWRRYYRLLLANRE
                     IAEDPTLAIDTPQAAERFPKTLSEAQVEALLAAPGLDTPQGLRDRCMLEVLYAAGLRV
                     SELVGLKVFAVGVNEGVVRVMGKGSKERLVPLGEIAADWLQRYLAEARPLLLAGRSCD
                     EVFVTRLGAAMSRQMFWRLIKQYALAAGIAPERISPHTLRHAFATHLLNHGADLRVVQ
                     LLLGHADISTTQIYTHVARERLKQLHARHHPRA"
     gene            55975..56463
                     /gene="ybaK"
                     /locus_tag="P5537_01715"
     CDS             55975..56463
                     /gene="ybaK"
                     /locus_tag="P5537_01715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HRV76789.1"
                     /translation="MSRNEAHAPETPATRFLRQHGVAFSSHLYEYEEHGGTTVSSREL
                     NVPEHAVIKTLIMEDENAQPLVVLMHGDHKVSTKELARQIPCKHVETCKPETANRHSG
                     YLVGGTSPFGTRKKMPVYMERTVLDLPLIYINGGRRGFLVGIHPHDLLRVLQPRLVQV
                     AN"
     gene            complement(56483..56857)
                     /locus_tag="P5537_01720"
     CDS             complement(56483..56857)
                     /locus_tag="P5537_01720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004383266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HRV76790.1"
                     /translation="MDFIFIEELRVKAWVGIYAREKTGPQTVELNLTFGVPDAAAEHD
                     DIADTIDYAVVTERIRRELGERHFNLIESLGEFVVKLLFEEFGAPWVKLKVGKIGVMK
                     DVRRVGVYIQRSKAGVVVPPAA"
     gene            57037..57645
                     /gene="plsY"
                     /locus_tag="P5537_01725"
     CDS             57037..57645
                     /gene="plsY"
                     /locus_tag="P5537_01725"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HRV76791.1"
                     /translation="MSTLLLIVAAYLLGSIPFAIVTSRLFGLEDPRKYGSGNPGATNV
                     LRSGNKAAAVLTLLGDALKGWLAVWAALRLGFEPDIAALAGLAAFLGHVFSLFLRFNG
                     GKGVATALGVLAGVDARIAIFCAVIWLMVAYTTRYSSAAALSAALAAPLAGFLFLGAK
                     PAVAVLAVMTAVLFWRHKENIARLRAGTEGKIGGKKKDGPTA"
     gene            complement(57909..58949)
                     /gene="tsaD"
                     /locus_tag="P5537_01730"
     CDS             complement(57909..58949)
                     /gene="tsaD"
                     /locus_tag="P5537_01730"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HRV76792.1"
                     /translation="MKVLGIETSCDETGVAIYDTEAGLRAHCLHSQIDLHAAYGGVVP
                     ELASRDHIRRLPLLLRQTLAEAGLAAADVDAVAYTSGPGLAGALLVGASVAESFAMAR
                     GIPALPVHHLEGHLLSPLLSADPPAFPFVALLVSGGHTQLMRVRGVGDYALLGESVDD
                     AAGEAFDKTAKLLGLGYPGGPQLAQLAESGVPGRFRLPRPMLHSGDLDFSFSGLKTAV
                     LNVVSAPDWDPVRMADLAAEFQQAVVEVLCAKALAALKKVGLKTLVVAGGVGANRCLR
                     ATLDAALARRGGRVHYPEPALCTDNGAMIAFAGALRLAAGETGPEVAAVRIRPRWPMV
                     ELRPPVQVSGVV"
     gene            59086..59298
                     /gene="rpsU"
                     /locus_tag="P5537_01735"
     CDS             59086..59298
                     /gene="rpsU"
                     /locus_tag="P5537_01735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011484193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HRV76793.1"
                     /translation="MPGIRVKENEPFEVAIRRFKRTIEKTGVLTELRSREFYEKPTAE
                     RKRKLAAAVKRNHKRLRSQTLPPKLY"
     gene            59459..61354
                     /gene="dnaG"
                     /locus_tag="P5537_01740"
     CDS             59459..61354
                     /gene="dnaG"
                     /locus_tag="P5537_01740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of RNA
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HRV76794.1"
                     /translation="MIPQSFVQELLSRVDIVDVIERYVPLKKSGANYFACCPFHGEKS
                     ASFSVSPSKQFYHCFGCGVHGSAVGFLMEYSGLGFVDAVKELAAQVGLQVPDDGRSAT
                     PAHDDASERLYEAMAMAARFYRDQLKPSRAAIDYLKRRGLSGEIAARFGLGYAPDEWQ
                     ALERIFPDYQAKTLADAGLVIDNEQGRRYDRFRNRIIFPIHDRRGRIIAFGGRVLGKG
                     EPKYLNSPETPLFEKGRELYGLFLAQKAIRDAGFAVVVEGYMDVVALAQFGIENAVAT
                     LGTATTPQHIHTLLRQTDRIVFCFDGDAAGRRAAWRALENALESLRDDATLAFLFLPA
                     EHDPDSFVRAEGAEAFRKAALAATPLGSFLIQELCGRHPLDSAEGRAAFVHESAPLVT
                     RIAAPLLKLQVVKAVAETAGMTQGEVEYAFEQLAASAPRRRGTEAPTPARAPATSPPS
                     AEADAPFLDEARPPARSTPPRGQAPRPRPGGRRKLPSTAGTLLRLVMQHPTWAARMPV
                     GLVPDDSPEGLALIAIIDLFSLGEPIPAGGLGALIERFRETPHADTLSRVAAELVEAE
                     FDEAVVETLFEDALRKLQVDGIGKEIAALLQRDREQGLDAAGRHRLGELLLEKRNLAG
                     GGKVSDL"
     gene            61403..>62795
                     /locus_tag="P5537_01745"
     CDS             61403..>62795
                     /locus_tag="P5537_01745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor region1.1
                     domain-containing protein"
                     /protein_id="HRV76795.1"
                     /translation="MAREKAKDPRKDAPAKGRPAKAKDKSAPVIESPAATPLDAEVRR
                     TRLKTLITLGKERGYLTYAEISDHLPDDVADAEQIEGIIATFNNMGIQVYDEAPAAED
                     LLMSDSVATNVDEDVAEEEAEQALSSVDSEFGRTTDPVRMYMREMGTVELLTREGEIE
                     IAKRIEDGLKHMVQAISACPTTIAEILAIVDRIAADEAKIDELVDGLIDPNAGSADEA
                     AAEEEATEDDGEAEEDEGAGDEDEGDEEEDSAESAERANAASLLQLKNDALARFDVIR
                     GLYAKKMQALEKRGSQDLSYLALQQQISDELLNIRFTAKAIEKLCDSVRHMVEQVRSH
                     ERQILQLCVDRAGMPRQHFIKVFPGQEVNLDWLKDEIAAGKNYADGLMRIHPAVLEEQ
                     QKLIDLQDRIGIPLKELKDINRQMSTGEAKMRRAKREMTEANLRLVISIAKKYTNRGL
                     QFLDLIQEGNIGLM"
BASE COUNT         9580 a        23265 c        20928 g         8922 t
ORIGIN      
        1 ccctcataac gggggaggag acgagaggcc atcctgcggg atggcctttt ttcgtttcct
       61 gggcgagaaa catgcgcact tcgatcgaag ctcctgcagg agcggcgcga gccgcgaaca
      121 ggcggtgacg aggcgatatg cgtcggcggt atcgcgccgc cgcattcgcg cctgccggcg
      181 ctcccacaaa agacaccggg gccaccccgg agggcggccc cggacctcga agccagacgc
      241 gaaagggggt gagcgctcag ccgcggcccg gtcccatgcc gccgccatca cgcgggccgc
      301 cgcccttcat tccgcgctcg cccttgcgcc ccatcttctg gaactccgca tcgaacacgg
      361 tcttctgcgc atcgctcagc gtcgcataga aggtctcgac cgacttgcgc gcctcgccca
      421 tctcggcctg gcgcagcttg ctcatctcct ccatgcgctg catgcgctcg atcgccgtct
      481 tcggctggcc cgcggcgcga cgctcggcca tggtcgcagc catgcgctcg gcgcgcgcct
      541 tcatgtcggt cttgaagcgc tcgaaggcgg gcttctgctc cggggtcagc gccagcgcca
      601 gctccaggcg cgccatgtgc aactcggcgc gctcggccat cttcgccttc atctgctcgg
      661 gcgccatctg cgaccagccg gccttgccgc cgcgcgggcc gtcgcaatgt ccgccccagg
      721 ccagcgcggc ggtgctgccg atggcgccgg tcgcgatgac ggcggcggcg atcgaggtct
      781 tgatccagtt tttcatgatg gctctcctgt gggttgcttg tccgtgttgc ccgtccgttc
      841 gggcgacgga gccatttgaa caccgcgatg taagcccggt ttgtccgggc ggcgcgcgtt
      901 tgcagcctga tgtctcgcta gcgcgcgcag atacgctggg atacaaagcc ggcaccgccc
      961 ggccttatga tccaggccat ggagaacccc gcatgaacac gtccgaccac gtcctgatcg
     1021 tcgatgacga tcgcgacatc cgccagctgc tcgccgacta cctcgagaag cagggcctgc
     1081 gctgcaccac cgccgccgac gggcgcgaga tgaaggccgc gctcgagacc caccgcatcg
     1141 acctgatcgt gctcgacctc atgatgcccg gcgaggacgg actcaccctg tgccgcaacc
     1201 tgcgcgcgag cggcgggccg cacgccaaca ccccgatcct gatgctcacc gcgcgcggtg
     1261 aggatatgga ccgcatcatc ggcctcgaga tgggcgccga cgactacctc gccaagccct
     1321 tcgtgccgcg cgagctgttc gcccgcatcc gcgcggtgct gcgccgcaca cgcgcgctgc
     1381 cgcccaacct cgacgccgcc ccacccgcca acgcgcgcct gctgcgcttc gcgcactggt
     1441 gcctggacac ggtcaaccgc cacctggtcg acgccgaagg cacggtggtc gcgctctcgg
     1501 gcgccgaata ccgcatgctc gcagtcttcc tctcgcaccc gcagaaggtg ctgtcgcgcg
     1561 accagctcat ggagctcacc cagggtcgcg aggccgacgt gttcgaccgc tcgatcgacc
     1621 tgctggtgag ccgcctgcgc cagcgcctcg gcgacaacgc gcgcgagccg gcgatcatca
     1681 agaccgtgcg caacgagggc tacgtgctcg ccaccgaggt cgccgctgaa gtcgacacca
     1741 gcaccgcagc gccgggcgga ggcggcccgc gatgaggctg ccgctgccgc gcagcctgtt
     1801 cgcccgcctg atgctgatct ggctggtcgg catcgcgctg gtgctcgcgg tgagcctcgc
     1861 gctcttcctc ggcgagcgcg agcgcatcgg ccgcagcgcg ctgttcgagg gcgtggcgca
     1921 ggagatcgcc agcgtcgccg acctgctcga cagcatgtcg ccgcccgagc gcgcgcgctg
     1981 gatcgacgag atcggccgcc gccgcctgcg cctcgccttg cgcccacccc acgatcggct
     2041 gcgtccgctc gccgaggacc accccctcca cgccgccctg cgcgaggcga tgccgcaacg
     2101 cccggcaacg ctgtacaccc atccgcgcga cgaccgcccc caccccggcc tggcgatcgt
     2161 gctcgcgctc accgatggca ccccgttgca ggtgcgcctg ccgggcatcc cgccggcgcc
     2221 gccgatcatg ccgcatcagc gcggcccctt cctggccgcg ctcgccgcgc tggtgctcgg
     2281 cgtcggcctg ctcacctgga tcgcggtgcg catcgccacg cggccgctgt cgcgcatggc
     2341 ggaggccgcg cgcgcgctcg gcgaggaccc gacgcgggcg cccatggaca cccgcggtcc
     2401 caccgaggtc gcccaggccg ccgccgcctt caaccagatg cagcagcgcg tcgcggagca
     2461 cgtcgccgag cgcacccgca tcctggcggc gatctcccac gacctgcaga caccgatcac
     2521 ccgcctgcgc ctgcgcgccg agatggtgga tgacgagggc ctgcgcgcgc gcatccagtc
     2581 ggatctggac ggcatgcagg gcctggtcaa ggagggcctc gcctacgcgc gcagcctgga
     2641 cgagcgcagc ccggcgcagg cgatcgagct cggccccctg ctgcaagccc tcgccgagga
     2701 cgcgcgcgac atgggatgga cggtgcgcgt gcccgaggac gtgcggggcc gtgtcgtcgg
     2761 caacccgtcg gcgctgcgcc gcgcgctgtg gaacctggtc gagaacgggg tgaagttcgg
     2821 cggcgaggtc gagctcacgc tcgcctgcgg tggcgagcaa tgcgagatcc gcgtccgcga
     2881 ccacggccca ggcctcgccg aggacgagct cgagaaggtg ttcgagccct tctaccgcac
     2941 cgaggcctcg cgcaatcgcg agaccggcgg taccgggctg gggctcgcga tcacccgcaa
     3001 cctggtgcac gcccagggcg gtgcgatcac gctgcgcaat caccccgggg gcgggctgga
     3061 ggcggtgctg cggctgcgcg cgcagtagcg cgcggcgagc gcgaggaagg cggcgagctc
     3121 ggcctcgcgc cgcggcgcgc tccagcccag ttcatgggcg acgatgtcgg ccaccgctgg
     3181 cgccaccgcc gcggcggccg cggcgtcgag gaagagcgca cgactgcggc gcgcgagcac
     3241 gtcctcgatg gagagcgcga agtcctcgcg cagcgcgcgc cgcaccgcgg cggcgccggg
     3301 caccaggccg ggcggaagcc ccgggggcgt gcccggcaag gacgcatcaa cgcccacttc
     3361 tccctcgccc tccgcaccag ggcgcacgcc gcagtcgagc gccagcgtcg ccgtcggcga
     3421 actccgctgc gccagtccgc cgaccgcctc gaccgcatcc accgcctcct cggccatcgc
     3481 acgataggtc gtccatttgc cgccgagcac gctgaccagg ccctgcgtcg agacctcgac
     3541 gcggtgctcg cgcgagatcc ggctgctggc gccgccccgc tcgcccccgc cttcaccctc
     3601 gcgctccccg agcaagggcc gcaggccgac gaagacgctg cgcaccgcct cgcgcgccgg
     3661 cgggcgccgc agccagcgcg ccgcggcggc cagcaggtcg tccacctcgc ccgcgagcgg
     3721 ctcgggttcg tccggcgcgt ccgtgcgcgg cgtgtcggtg gtgccgatca gcacctttcc
     3781 gccccagggg atcatgaaca gcacgcgccc gtccggcatg cgggggacca gcagcgcgtc
     3841 accaccgggc aggcagtcgg cgtcgaccac cacatgcacg ccctggctcg ggcgcagcag
     3901 gggccgggcg gcgggatcgg cgcgccggcg cagcgcatcg ccccacaccc cggtggcgtt
     3961 gatcaccgcg cgcgcggcga tgcggtagtc gcgcccaccc tcggcctcgc gtaccaccac
     4021 gccgcacagc cggccgtcct cctccaccag ctcgagtgcg gcgcagtggt tgagcagcag
     4081 cgcnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4141 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnngtctcga gcaggcgtgg
     4201 acgcagcacc ggcacgccga gcaggtcggc ctgcagctgc atcagcaggt cgttggccgc
     4261 ggcaccgcca tcgacgcgca gctcggcgag cggcgcggcg ccgtctcgcg ccatcgcctc
     4321 gacgaggtcg gcgctctgct cagcgatcgc ctcgagcgcc gcgcgcgcga tgtgcgccgc
     4381 gccgctgcca cgcgacaggc cgagcagggt gccgcgcgca tgcgggtccc agtagggggc
     4441 gcccagcccg gtgaaggccg gcaccagcac caccccgccg ctgtcgggca cgctcgccgc
     4501 cagcgcctcg acctcggacg cacgctttac cagcccgagg ccgtcgcgca gccactgcac
     4561 caccgcgccg cccatgaaca cgctgccctc gagcgcatag ctcggcgacg cctcgacgcc
     4621 ggtccagccc accgtggcga gcagccggtt ggtcgaggcc accggcgcat ggccggtgtt
     4681 catgagcaaa aagcagccgg tgccgtaggt gttcttcgcc atgcccgggg cgaggcaggc
     4741 ctggccgaag gtcgccgcct gctggtcgcc gccgatgccc gcgatcggga tcgcagcccc
     4801 gaacagcgcc ggatcggtct ctccgcacac cccgctgctg gccaccacgc gcggcaacaa
     4861 ggcgggcggg atgcggaagc gctcgagcag caccgggtcc cagtccatcg agtgcaggtt
     4921 gaagagcagc gtgcgcgcgg cgttgccggg gtcggtcaca tgcagccggc cgccgctcag
     4981 gtgccacacc agccagctgt cgatggtgcc gaaggcgagc tcgccgcgct cggcgcgggc
     5041 gcgcgcatcg gggacgtggt cgagcagcca ggcgagcttg gtggccgaga agtacggatc
     5101 gagctccaga ccggtgcgca cgcgcacgtc ctcggcccag cccgcggcgc gcaggcgctc
     5161 gcactcggcc gcggtgcggc ggtcctgcca gacgatcgcg ggggcgagcg cacgcccgct
     5221 ggcacgctcc cacagcacgg tggtctcgcg ctggttggcg atgccgatgg ccgccacctg
     5281 gcgtgcggcc accccggcgt tggcgagcgc ctcgcgggcg caatcgaact gggtgcgcag
     5341 gatgtcctgg gggtcgtgct cgacgcggtc gggcgccggg aagtgttgcg cgaacgcctg
     5401 ctgggcgagg ccgcgcacac gaccgccggc gtcgaacacg atcgcgcgcg agctggtggt
     5461 gccctggtcg agggcgagca ggtaggccat ggcgactccg cacgggggct gaccgggatg
     5521 ccatgagcct agcgccggac gcgctccggc gccaccccgg gaaagccacg atgtgattca
     5581 atggaggccc ttcgttgcag cgcagcaacc gccatgcccg cattctggat gatcgtctcc
     5641 tgcttcctgt tcgcctgcat gggggtgtgc gtgaagctgg cgtcgggggt gttctcgacc
     5701 ggcgagatcg tgttctggcg cgggctcgtc agcatgctga tgatggtggg cctggcggca
     5761 agccgcggca tcgggctgag gacgccgcac tggaagatgc acctgtcgcg cagcgtgtcg
     5821 ggctcgatcg cgctcggctg ctacttcttc gcgatcggcc tgctgccgct ggcgaccgcg
     5881 gtgaccctga actacacctc gccgctcttc gtcgccctgg tgctggcgct gttcttcggc
     5941 gagcgcctgc gcggccccgc cgtgcttgcg atcctcgccg gcttcgccgg cgtggtggtg
     6001 ctgctgcgcc cgacgctgca gccggaccag tggctgggcg cgctcgccgg gctggcctcg
     6061 ggggccctgg ccagcctcgc ctacgtgagc ctgcgcgagc tcggccgcgc cggcgagccg
     6121 gaggtgcgca cggtgttctg gttctcggtc atgacctcgg cgatgggcct ggcgtgggcg
     6181 ctcgccggcg agctgcaccg gcccgacggc ctgcagctcg ccaccctgct cggcgtcggc
     6241 ctcttcggcg ggctggccca gctcgcgatg acgcgctcct accgctacgg ccgcaccgtg
     6301 gtgtcggcca acctgagcta cgccacggtg atcttcgcca gcctgttcgg catgctgctg
     6361 tgggacgaga tcatgccggc ctcgtcctgg ctcgcggtgg ggctgatcgt ggccggcgcg
     6421 atcggcgtct cgctcgccac cccgaagccg tcgccgctgc cggcacgcgc cgcggcgacg
     6481 gattgagcac ggcctgtgcg cggactatag tggggacatc ttcgatcctc accttcaggg
     6541 aggctgccat gatcagcacc gagagcaccg aaagactcgt ctcgctcgtc gtcttcggcg
     6601 aattcaccct cgccgactac aaggagttcg aggacgtggt caattaccgc atccagttca
     6661 gcgggccggt cgacctcctc ttcgacctgc gccagatggc cggcttcacc ctcgacgtgg
     6721 cgtgggagga aatcaagttc tcgcgccagc acgcgggcga cttccgccgc atcgcggtgc
     6781 tcacgcagga ccagtggctg acctggagcg cctgggtgtc gcagctcttc gtgaccgccg
     6841 aggtcaaggt cttcgacgac gaggacgagg cgcgcgcctg gctggccgcc gacaccgccg
     6901 cagagaccgc gggcagcgcg cagtgaacgc ttcgtacgcg acgctgatcg gcgccatcga
     6961 gctcgcgccg catctgcgcg acgccgactg ggtcgtgttc gattgccgtg ccgacctcgt
     7021 cgacccggcc ttcggccagc gcgcctacgg ctcggcacac ctgccggggg ccttcttcat
     7081 cgacctcgag accgggcttt cggggccgaa gaccggccgc aacgggcgcc accccctgcc
     7141 cgatcccgcc agcctcgccg cccggctcgc cgcctgcggg gtgggcaacc acagccaggt
     7201 cgtcgcctac gacgacgccg gcggtatgtt cgctgcccgt ctgtggtgga tgctgcgctg
     7261 gctcggtcat gatcgtgtcg cggtgctcga cggcgggctg caggcctgga tggcggccgg
     7321 actggcgctc gacgacgagc cgccggctgc acgcccggcg acctataccc tggccttgcg
     7381 cccggaccgg gtcgatgcgc ggtacgtgca tgaacacctc ggcaggcccg acatgctgct
     7441 gctcgatgcg cgcagccccg accgcttccg cggcgagaac gaggtgctcg atccggtggg
     7501 cggacacatc cccggcgcgc gcaaccgctt cttccgcgac aacctcgacg agcgcggctg
     7561 cttcaagcag gcctcggtgc tgcgcgagga gttcaccagc ctgctcggcg cacacacgcc
     7621 acgccaggtc gtgcatcagt gcggctcggg cgtcaccgcc tgcgtgaacc tgctcgcgat
     7681 ggagtccgcc ggactgaccg gctcgcgcct gtatgcgggc tcgtggagcg aatggtgcgc
     7741 cgaccccgaa ctgccggtgg cgcgcggacc ggcctgaagg ggcacggacc cggactttct
     7801 gcagcgcgag cgaacgctac cagtcgacct tctccaccgc gccgagggaa cgcccgagga
     7861 agcgctcgcc gatggtctgg aagcgcagcg gcacgtcgct caccacgaaa cggtaatcgg
     7921 ccacgccgcc gccggtgcgc gccagtcccg cctgctgcag gcgctcggcg gcgagttccg
     7981 cagtggtcag cgccgaatcg atcagccgca cccgcggccc ggcgacgtcg cgcagcagcg
     8041 gcttgagcag cggatagtgg gtgcagccga gcaccaggct gtcgacctcc tcggcgagca
     8101 ccgggcgcag gtactcctgc gcagtgagcc gggtgacctc gtggtccagc cagccttctt
     8161 cgaccagtgg cacgaacagc gggcaggcct gcgaatatac ccgcaccgcc ggatcgagct
     8221 cgtgcatgcg gcgcgcatag gcgttgctgt tgatcgtggt gggcgtgccg atgacgccga
     8281 tgcgccgccc cggcgaggct gcgaccgcgg cgcgcgcacc ggcctcgatg acgtcgagca
     8341 ccggaatgcc ggcggccagc cggtgcacca cctccgccgc caccgcggcc atggtgttgc
     8401 aggcaatgat cagcatcttc acgtcgcgct gcagcaggaa ctcggtgatc tgcgcggtga
     8461 agtgctcgat cgtggcgacc gacttcaccc cgtagggcac gcgcgcggtg tcgccgaaat
     8521 agacgatgtc ctcgagcggc aggcgctcca tcagcgcacg caccacggtg agcccgccga
     8581 cgccggaatc gaacaccccg atcgggcgcg acgccgcgct catcgcccgg ccccgctgca
     8641 gggggcgcga tcggtcaaga cagcaccacc gaggcgaact tgcgcttgcc cacctgcagc
     8701 accacggtcg cgccggcgcg cagcagcagg cccttgtcct cggcacgctc gccgtcgatg
     8761 cgcacgccgc cctgctccac catgcgcatc gcctcggagg tggtgccggt gagcccggcc
     8821 tgcttgagca cctggaacag cggcagcccc tcggcgccga cgtttaccgt gacctgcggg
     8881 atgtcgtcgg ggatcgcgtt gcgctggaag cgcgcctcga agtcggcgag cgcctcctcc
     8941 gccgcgcgct ggccgtggaa gcgggcgacg aactccatcg ccagcatcac cttgacgtcg
     9001 cgcgggttgc gcccgccttc cacctcggcg cgcagctgcg cgatctcggc ggtggagcgg
     9061 aaggacagca gctcgtagta gcgccacatc agggtgtcgg acaccgacat ggtcttgccg
     9121 aagatctcct tcgccggctc ggcgatgccg atgtagttgc cgagcgactt ggacatcttg
     9181 ttcacgccgt ccagcccctc gagcagcggc accatcacca cgcactgggg ttcctggccg
     9241 taatgcttct gcagttcgcg acccatcagc aggttgaagc gctggtcggt gccgccgagc
     9301 tcgacgtcgg acttcatcgc caccgagtcg tagccctggc acagcggata gaggaactcg
     9361 tggatcgcga tcggctggtt gttgccgtag cgcttggcga agtcatcgcg ctcgagcatg
     9421 cgcgccacgg tctgctgcgc agccaggcgg atcatgccgg cagcgccgag gtcgttcatc
     9481 caggcggagt tgaagcagat ctcggtcttt tccgggtcga ggatcttgaa cacctgctcc
     9541 tggtaggtct tcgcgttctc caggatctgc tcgcgcgaga gcggcggacg ggtgctgttc
     9601 ttgccgctgg ggtcgccgat catgccggtg aaatcgccga tgaggaactg gacctggtgg
     9661 ccgagctcct ggaagtggcg catcttgttg atcaggaccg tgtggccgag gtggaggtcg
     9721 ggcgcggtcg ggtcgaatcc ggccttcacc cgcaagggct tgccgcgctt gagcttctcg
     9781 accagttcgg cctcgatcag cacggcgtcg gcgccgcgct tgatcaggtc gatcgccgcc
     9841 tgaacatcag acattcaatt tctccaaaat tactttgccg aaccgaagcg cacctttgct
     9901 acacttccga aaattttttc cacatcccag ccaccgagac catgaaggcc agaaggaccc
     9961 gaattctagc cgatctgccg gctcgactcc tctcccgccc gcgcacctgg attgccgccg
    10021 gtgtcaccgg ggtttccatc ttcggcgtgg tcgccgcaac cgcggtcgcg cctggcagcc
    10081 tgcccgccga cctgctcgtg gagcgcgtgg tcgaggccct gccgtcacct gcggtgacgc
    10141 gcaccgctac cgacccctcg ctgccctacg tccactacga acgcattcag ccgggcgaca
    10201 cgttgcaggc gatgttcaac cgcctgcgca tcgacgatgc cgaggcgctc gcccacctgt
    10261 cgggctccga cgccggccgc aaggcgctgc gtcagctgcg cgcgggccgc tcggtcaccg
    10321 cggtggtgtc gccgcaaggc cgccttctca gcttcgcgct gccggtcggc aacaccggcg
    10381 cgcaggtcgt cctcgaacgc ggcgacgccg ggctcgcgct gcgcgaatcg agcgccaccg
    10441 agcagaccat gatggtcgag atgcgctcgg gcacgatcac ccactcgctc ttcggcgcca
    10501 ccgacgacgc cggcctgccc gacaacgtgg ccacccagct cgccaccatc ttcggcacct
    10561 ggatcgactt ccacgccgac ctgcgcaagg gcgatcgctt caacgtggtc tacgaagcga
    10621 tctacgagga aggcaacccg gtgcgcgccg gtcgcatcct cgccgccgag ttcatcaaca
    10681 acggcgaacg ccacgcggtg gtcctctatc gcggcccgag cggcaaggag caatactaca
    10741 gcgacgacgg caaaagcctg cagcagggct tcctgcgctc gccgctggag ttcacccggg
    10801 tcagctccag cttcggccgc cgcctgcatc cgatccatgg cagctggcgc gaccataacg
    10861 gcgccgattt ctcggcaccg accgggaccc cggtgatggc cacttcggac gccaccatcg
    10921 agttcatcgg cacccagcgc ggcttcggca acctgatcgt gctcaagcac cgcaacgaca
    10981 tcaccaccca ctacgcccac ctcaacggct tcgccaaggg cctcgccaag gggcaggcgg
    11041 tgagccaggg cgacctgatc ggctacgtgg gctgcaccgg ctggtgcacc gggccgcacc
    11101 tgcactacga ggtgcgcctc aaggacgtgc ccgccgaccc gatgacggtc gcgctaccga
    11161 tggccgactc cttcaacgac aaggagctcg ccgccttcaa gcgcaacacc gcccacctgc
    11221 gccagcgttt cgcgctgctc aactacgagc tcgccgacgc acgctgaggg ctccgcgatc
    11281 gatccaaaac aaaacggggc gccgcggcgc cccgtttttt tgcgacgacc acgctcacac
    11341 ggtgaacgaa gagccgcagc cgcaggtgct ggtcgcgttc ggattgcgga tcacgaactg
    11401 cgaaccttcc agcccttcgg tgtagtcgat ctccgcgccc accaggtact ggtagctcat
    11461 cggatcgacc agcagcatca cgccgttctt ctcgaacgtg gtgtcgtcct cattcacttc
    11521 ctcgtcgaaa gtgaaaccgt actggaagcc cgagcacccg ccgcccgaca cgaagacgcg
    11581 cagcttgaga tcgggattgc cttcctcttc gatcagctcg cgaaccttgt tcgcggcgct
    11641 gtcggtaaag accatgattt ccggggttgc gacttctgcg ctcatgtttt ctcctctgct
    11701 gggggacacc gcggatgatg cgccttccgc gatcgaatcg tcaaaatgtg atcgaatccg
    11761 gccgaaacag ttccctcagg ggctgaccgg cacgatgtcg agcccggttt cctcgtcgaa
    11821 accgaacatg atgttgaggt tctgcaccgc ctgaccagcg gcgcccttga ccaggttgtc
    11881 gatcaccgac agcaccacca cggtgtcgcc gccctgcggg cgatgcaccg cgatgcggca
    11941 caggttggag gcgcgcaccg agcgcgtctc ggggtggctg cccgcaggca tcacgtcgac
    12001 gaaagcctcg ccggcatagc gcttctcgta cagcccctgc aggtcggccg cgtcgacgcc
    12061 cggcttcagg cggccgtaca gcgtggcgtg gatgccgcgg atcatcggcg tcaggtgcgg
    12121 cacgaaggtc agcccgaccg cgcggccggc cgcgagcgcc aggccctggc gaatctccgg
    12181 caggtggcga tgacccggca caccgtaggc cttgaacgag tcggcggcct cgggcagcag
    12241 cgtgtgcacc tcggccttgc ggccggcacc cgagaccccc gacttggcgt cggcgatcag
    12301 atgatcggta tcgatgagcc cggcctcgac caggggcagg aagccgagtt gcaccgcggt
    12361 cgggtagcag cccgggttgg cgagcacgcg cgcgccacgg atctgttcgc ggttgacctc
    12421 gggcaggcca tacaccgcct cggcgacgag ctcgggcgcg gcatgctcca tgccgtacca
    12481 cttctgccac tcggcaacgt cacggatacg gaagtcggcg gcgaggtcga tcacacgcac
    12541 cccggcggca accagctcgg ctgcctgctt catcgcgatg ccgttgggcg tggcgaagaa
    12601 caccgcgtcg cacttctcca gcgcggcgtc ctgcggggtc acgaacttga gatccacccg
    12661 acggcgcagg ctcggaaaca tgtcggacac ggccatgccg gcctcgccgc gcgaggtgat
    12721 cgcgcccagc tcgaccccgg ggtggcgcgc cagcagacgc aagagctcga cgccggtgta
    12781 tccggtgccg cctacgattc caaccttgac catgctcgtt cctcgcgacg aaagactgaa
    12841 gcgcgattat ctcaccatcg gccgacgcgg gcggtgaacg ccgcgttacg gccgccgccc
    12901 ccgcgccgca taagtcctcg cgagcgggac gcacaagcac gaaagccgcc caaggggcgg
    12961 ctttcgaact gcgatgcgcg atgacgggat cagcgcttcg agaactgctt ggcgcggcgg
    13021 gccttgcgta ggccgacctt cttgcgctcg acctcgcggg catcgcgggt cacgaagccg
    13081 gcggcacgca gatcgccctt caggccggcg tcgtaatcga ccagcgcgcg ggtgatgccg
    13141 tggcgcaccg cgcccgcctg accggattcg ccaccgccga ccacgttgac catgatatcg
    13201 aagcggcctt cgttgccggt gaggaccagc ggctggcgca cgatcatgcg gccggtttca
    13261 cgcgagaaaa actcgtcgac cggcttgccg ttgacgacga tgttgccggt gcccggcttg
    13321 atgaacacac gagcgaccgc agtcttgcgg cggccggtac cgtagttgta agtgacagcc
    13381 atctatcggc tccttcagat ctcgagaact tgcggctgct gagcggtgtg cggatgcgac
    13441 ggacccgcgt agcacttcag cttcttcagc atggcgtagc ccagcgggcc cttcggcagc
    13501 atgcccttca ccgccttctc gagcacgcgc tcggggaagc gctgctggag cttggtgaag
    13561 ttggtttcgt agataccgcc cgggtagccc gagtgacggt agtacttctt gtcctgcgcc
    13621 ttgttgccgg tcacgcgcag cttgtcgacg ttgaccacga cgatgaagtc gccggtgtcc
    13681 acgtgcggag tgtagatggc cttgtgcttg ccacgcaggc ggcgggcaac ctcggaggcg
    13741 agacggccaa gcaccttgtc cgtgccgtcg acaacgaacc agtcgcgctt gacctcgtgc
    13801 ggcttggcgg aaaacgtctt catgtgaatc ctcgatcttt gtcgggccgt cggagatggc
    13861 cgtcaaacgg aaagctcgca atcctacttc caacacatga agcgtgtcaa tcatcgaagc
    13921 gcgaacgcgg gcgaagaaca aaaaaaacgc agtccaatcg gactgcgtta aatccacacc
    13981 aaaggaggag ggtggaggag acaccatttg gaccggcgcg aactcctgac ctgggagccg
    14041 atgcgtctgc gatccgactg gaacggatta tgcatagccc ccaagacgcg tgcaaggcat
    14101 ttttgtgcga cgcgggagaa aagttttgat tgttttatca actcccttta ttcattggca
    14161 gctttttgtt ttaaatcaat tttcgctctt cctgcgggcc tgccctgccc ttgcggaaga
    14221 cgtccggcat cctcctcacc ctccgttttg ctgcactgca tcactacgga gccgtattga
    14281 agtcgtgcgc atcgcgccgg cgccccgggc acacccccgc aatactgcgc aggcgacggc
    14341 gaggcgacga tccgcgtggc acacacgaag tccatgacgc actgcggtaa catgccgcct
    14401 caccccccaa cgaacccgac aacgggacca gaacccgaag gagcgaacag catggaatgc
    14461 acggtcaagt ggctggacgg catgagcttc atcgccgaga ccggcaccgg tcacatcgtc
    14521 gcgatggacg gcgcgcccga cgccggcggg cgcaaccttg ccccgcggcc catggagctg
    14581 ctgctggccg gcgcaggcgg ctgcaccgcc ttcgacgtga tgctgatcct caagcgcggg
    14641 cggcacgacg tgcgcggctg cagcgtacgt ctggaagcgg atcgcgcgga gtccgacccg
    14701 aaggtattca cccgcatccg cttcatctac acgatcaccg gccgcaagct caagcgcgag
    14761 acggtcgagc gcgcggtgca cctgtcggcg gagaagtact gctcggcctc gatcatgctc
    14821 ggcaagaccg ccgagatgat ccacgagatc gagctgatcg aggcggactg aggatcgagg
    14881 cgtcgcgagg aagccctcac gacgcggacg agggcgcggg agtcgctcag agccggtagg
    14941 cgagcgtggt catgactctt gcggcgagct tcatcgcagc cttcgccggc gcgggcagct
    15001 cgtgcgcacc caggcgcagc gccgtctcgg cgtgctcggc ctcatccacc ttcatctgct
    15061 cgacgatcgc gcgcgagcgc cgatcggccg ccggcagcgt gtcgagatgg gtcttgaggt
    15121 gctgctcgac ctggcgctcg gtctcggcca ggaagccgag gttccagcgc tcgccgaagc
    15181 gccccgccgc cagcccgagg gcgagcgcgc cgccgtacca caacggattg agcaggctct
    15241 tgcgcccacc gagctcggcg atccggcgct cggtccacgc caggtgctcg gtctcctcct
    15301 gcgcggcctg gcgcagggtg tcgcggatcg cgggatcgcg cgacatgatg gactgcccct
    15361 ggtagagcgc ctgcgcgcac acctcgccga cgtgattcac gcgcatcagc gcggccgcgt
    15421 ggctgcgttc ggtttcgccg agttcggcat cgggaacgtc ctcgccgggc accgcgcgca
    15481 cgctgcgcgc cggcgcgaag accgtccgca gcgccttgtc gaactcgatg atggcctgat
    15541 cgatcattgg tggactccaa acggtttgtc gaggtcgcgc ttctgacgca gcaggcgcag
    15601 ggcgtgttcg cggtcgcgcg ggccagccgg accgtcgcag aagtagtcgt gcgccagcgc
    15661 cgcgcgcggg cggttgtagc cattgtcgac gatgggctgc caggcgctgt tcttcagcgg
    15721 cgaccacgtc ccgtccttgc gcccgctggc atagatccgg cgctcgccgg tggcgcagcg
    15781 gatgccctcg aagctgacgt tctccgcccc gccgcgcgcc cgaacgacca gggtgtagcg
    15841 caccacgcca tcggccccga cggcgacact gtcctcatcg acgaagaagg cattgggcga
    15901 gggcgtgccg atgtcgatca tgcgcagcgc ggcctcgcgc ggtgcggccg gcatggccac
    15961 ctcgccctcc ttccagtcgg gatcggcctc gagcagcagg cctgcggacg caggcaccca
    16021 gacggccgcg aggagaaggg cgccggcgcg cagccgatcg gcgaggagac agttcaagga
    16081 tcggaactcc acagcgagat tgcagaagac gggcacgccc caccgccgga cgaccgtcag
    16141 cggggcatgt cccgggagca gcgcgaacga taccggcccg cacgccagca gacggcgaac
    16201 ggcccgccag gcgaggcctt gcccggtccg gctacttccg gatcgcatcg cgcagcccgc
    16261 gctcgccgat caccacccgc accggctcgg gagcaggctc aggctcgggc agccggtagc
    16321 tgtcgggcag ctcgaagctg cgcgaccgga acaggatgcg cgccaattcg atcagcgcca
    16381 gctgatagac ctggcgcttg aactcgatca ccgcttccag cggcacccag tagttgctcc
    16441 agcgccaggc atcgaattcc ggatgagtgc tcgcgcgcag gcagacgtcg gagtcgcgcc
    16501 ccaccaggcg aagcaggaac cagatctgct tctgtccacg gtaggtgttg cgccactcgc
    16561 gccggatcca gtgcttggga acctcgtagc gcagccaccc gcgcgtgcgc ccgagaatcc
    16621 tgacgtgctc gggccgcagt ccgacttcct catggagctc ccggtacatg gcctgctccg
    16681 gcgactcgcc gtgcttgatg ccaccctggg gaaactgcca ggaatgttcg cggatgcgct
    16741 tgccccagaa cacctcattg cgcgcattga ccagaatgat gccgacgttc gggcgaaagc
    16801 cttcacggtc aagcatgacg aaccttcgaa ttcgtttgat tggtcacgat tttttcacac
    16861 ttggccacgc aatgaaagcg caccgccgtg gcgcgtcggc taagctgaag gccgacgaac
    16921 gcttgcgcgc cggccccatg cgctagaatc gcgcgcttgt tcacgcctga tccgaagact
    16981 cccatgcgcg ccagccagtt ccacctgttc accctcaagg aagccccctc cgacgccgaa
    17041 gtcgtcagcc agaagctgat gctgcgcgcc ggcatgatcc gcaagaccgc cgccggcatc
    17101 tacagctaca tgcccatggg cctgcgcgcg atccgcaagg tggaggccat catccgcgag
    17161 gagatgaacc gcgccggtgc gatggagctg atcatgccgc tggttcagcc cgccgagctg
    17221 tggcaggaga ccgggcgctg ggacaagatg ggcgccgaga tgctgcgcct gaaggaccgc
    17281 cacgagcgcg acttcgcgct gcagcccacg tccgaggaag tcgtcaccga catcgcgcgc
    17341 caggaactca agagctaccg ccagctgccg aagaacttct accagatcca gaccaagttc
    17401 cgcgacgagc gccggccgcg cttcggtgtc atgcgcgggc gcgaattcac catgaaggac
    17461 gcctactcct tcgaccgcag cgaagaagcc gcggggcgca gctacgacag catgttcgcc
    17521 gcctacaagc gcatcttcga ccgcctcggc ctcgagtacc gcgcggtggc ggccgatacc
    17581 ggcgccatcg gcggcgaccg ctcgcacgag ttccaggtca tcgccgacac cggcgaggac
    17641 gccatcgtct actgccccga ctccgactac gccgccaaca tcgaactcgc cgaggccgtg
    17701 tctttgctcg cgcgccgcgc cgagccggcc aaggcgctgg agaagacccc cacgcccggc
    17761 aaggccacct gcgaggacgt cgccgcgctg ctcggcgtgc cgctcgccac cacggtgaag
    17821 tcgctggtgc tcgccaccga cgacctcgac gacaagggca atccggccgg cgtcaccgtg
    17881 tggctgctgc tggtgcgcgg cgaccacgcg ctcaacgagg tcaaggccgg caagctgccg
    17941 ggcctgaagg ccggtttccg cttcgccacc gagggcgaga tcctcgagca cttcggttgc
    18001 aagccgggct acctcggccc catcggcctg ctgaagccgg tcaaggtgat cgccgaccgc
    18061 acggtcgccc acatggccga cttcatctgc ggcgccaacg acgccgactt ccacttcacc
    18121 ggcgtgaact ggggccgcga cctgcccgag cccgacctgg tggccgacct gcgcgacgtc
    18181 gtcgagggcg accccagccc ggacggcaaa gggatgctcg ccatccagcg cggcatcgag
    18241 gtcggccacg tgttctacct cggcaccaag tactccaagg cgatgaacgc caccttcctc
    18301 gacgaggacg gcaagcccaa gcacttcgag atgggctgct acggcatcgg cgtcacccgc
    18361 atcctcggtg ccgccatcga gcagaaccac gacgcccgcg gcatcatctg gccgcgcgcg
    18421 atcgcgcctt tcgaggtggt gatctgcccg gtgggctggg gcaagtcgca ggcggtacgc
    18481 gacgaggcgc agaagctcta cgacgcgctc gttgccaccg gcgtggacgc catcctcgac
    18541 gaccgcgacg agcgccccgg cgtgatgttc gccgactggg agctcatcgg cgtgccgcac
    18601 cgcgtcacca tcggcgaccg cgggctcaag gaaggcgtgg tcgaatacca gggccggcgc
    18661 gacgccgagg cagccaagct gcctgtgggc gagatcctcg gccacgtgct cgcacgtctc
    18721 gaccaggcct gatcccggga gacgccgcca tgcgccgcct gcccgccccg ctccgccagc
    18781 ttgccgccgc ctgtgcgctc gcgctcgcgg ccggcggggc gcaggccggg gcgcagcagt
    18841 acgagccgat ggcggccagc gtgcgcgccg cgctgcatgc cgcggtcagc gacgccgtgg
    18901 cgccgaccct gccgatcccc gacgccggcg agcgcgcgca gtggctcgcc gagatgtcgc
    18961 gccggctggc caagcgcatc ccggacgagg cctaccgcaa ggaactcctc accagcatcc
    19021 actacgaggc cacccgtgcc gggctcgacc cgcagatggt gctcggactg atccaggtcg
    19081 agagcgcctt ccgcaagtac gcgatctcct cggcgggcgc gcgcggctac atgcaggtga
    19141 tgccgttctg gatcaaggtc atcggtcgca cggacgacaa cctcttccac atgcgcacca
    19201 acctgcgcta tggctgcacc atcctccgcc actacctcga catcgagaag ggcgacctct
    19261 tccgcgcgct aggccgctac aacggcagcc tcggcaagcc ggactacccc aacctggtcc
    19321 gcgccgcctg ggagaggcac tggagctgga cgccgcagca gctcgccgcc gcaggctccg
    19381 cacggctgca ggcaggcgcc gcgacagcgc gctgacatcg caaggctctc gccaccagcg
    19441 ggccgggccg gacttggccg gcccgaagat tcgccgccgg gcggcaccga cccgcagggc
    19501 gccgcgggcc gcggcggcgc atccccgcgc acgcagcacc gctgcggtcg cgccatgcgc
    19561 gggcaagccc gctcccaagg ccgaacatgc ctcctgcgca ccgactcagc ccgccaccgc
    19621 ggcgagcgcc cgcggcttgt catcgaccgc gcgcagttcc ttgcctgctg cgctcagcga
    19681 ctgcacgtca ccggaaagct caccgccttc ctcgatgagg atcttgccgt agcggatctt
    19741 cccgctcacc cgcccgccgg cgtggatcag cagctgcttg cgggcggtga gctcgccctc
    19801 gaagtggccg tggatctcgg cgatgtcgat gccgaccgtg cccttgaagg cgcccttctc
    19861 cgcgatgcgc aacacgcggc tgtccatcgt cgcctcgacc cgaccctcca cgaccagggt
    19921 gtcgcagtcg aggatctcgg cccccttgag cttcacctcg gggcccacga tcagccgact
    19981 ctcgcccgcg accaccggcg cctcctcgcg cccgaccgcc tgcggctcgc gcgctgcgga
    20041 cgggccagcg gcctcggcag gctgcgcggc ggacgcggcg gcgacgttcg tgcctgccgg
    20101 gcgctggccg ttgcgctgtg cggacgactc gccgccgtgg aacagattgg gcttgttgaa
    20161 catgttctct cctggagtcc ggcgcagcta cggcgctgcg ctccgactgc tcatcagcaa
    20221 tccccatgcc agcagcgtct ttccctttcc gggcaggcac ttgcgacaaa gcgtgcgcgc
    20281 acggcccgac gcggacaggg ccgagctgtc gcctgcaccc gacacccagc ccggccggca
    20341 cgcgcaagca actgattcaa aaggctttcg tactgtcgtc cggcgacgac gccgatgtcc
    20401 gtcgcttact tcgtcttgca tttccgcggc tgcgcggccg cacccgctga cctagactcg
    20461 tcgtccccat cgccgcgcaa cgctgcgctg cacaagccga tccccgcatg cgtcacctgt
    20521 ccttccgcgc caccctgctc gcgagcttcc tgctgatcgc cgccagcctg gccgccgccg
    20581 tcgcgggcgg ctggcgtggc atggaagcgg tcgtgcacgc gatccaggac gacaagcagc
    20641 gcgcactcgc cctgagcgac gcggcgcgcg cgctcggcga gcgcagcgtg gaactcgagc
    20701 gcagcgcgcg ccagtacgag gtgctgggcg agccgaccct cgcccgacgc ttcgacgccg
    20761 ccctcgccga ggcacggcct gcgctggcgc tgctggagtc ggccagtccc gcgctcgccc
    20821 gcgaggtcgc ggcgtggcgc gttagcgccg accacgtcgc ggcgtggctg gcgagcctgg
    20881 ccgcccccca gcccgcagac cgcgcggagg aagacgcgcg cgaagacccg cagtccgcca
    20941 cgacgaccgg gcgcatcgcc ccccctgcag cggaagacga gctccgcagc ctcggcgtgc
    21001 gcgccggccg gctcgccgag gcgctgaacc agcacctcgg cgatcgtgac cgtgccctga
    21061 tgggcacgct cgaaggcgaa cgccgcgccg tcaccctgca gatcctcgcc gccctggtgc
    21121 tcgcaggcac gctcgccggg cttgccggct ggtggctgct gcgcccgctc ggccgcatcg
    21181 agcacgccat cggcgagctc ggcgagaatc gcctcgcccg cccgatcgac atcggcggcc
    21241 ccgccgacct gcgcaggctg ggcgcgcgtc tcgactggct gcgcctgcgc ctgaccgagc
    21301 tcgagtccga ccgcaagcgc gtgctgcgcc acgtgtcgca cgaactcaag accccgctcg
    21361 cctcgctgcg cgagggcgtc gccctgctcg acgacggcgt gctcggcacg ctcgcccccg
    21421 gccagcgcga agtcaccggc atcctcgcgc acagtgcgcg cacgctgcag gagcgcatcg
    21481 agcagctgct gcggctcaac gccagccagt tcgacgcgcg ctccctgcat ctgcagccga
    21541 ccgccctcct ccccctgctg cgcgaagtcg tcgaggagca gcgcctgccg gcacgcgcac
    21601 gcggcgtcac gatcaggctc gcgggcgagg cccccatcgt gcgcgccgac ggcgacaagc
    21661 tacgtaccgt gttctccaac ctgctcgcca acgcgatcgc ctacagcccc gccggcggcc
    21721 gcgtccgcat cgagctcggc ctcgccgccg agaacgtcgt gatcgactgc ggcgacgagg
    21781 gccccgggat cgaacccgac gagctcgagc gcatcttcga gcccttcttc cgcggccgcc
    21841 gcagtcctcc cgcaaaaacg ggcggcggca gcggcatcgg actggcgatc gtgcgcgagt
    21901 tcatctgcgc ccatcgtggc agcgtgcgtg cgctgccgag cgaccgcggc gcacatttcc
    21961 gcgtggagct gccccatgcc tgaccccgag ctccacctcg ccggcacggc gccccgcaac
    22021 gccctccgcg cactgctccc cgccacgctc gccctgctcg cgggctgcgc cggcgtgccc
    22081 gcctgggacg ccggcgagga cacggccagg gctgcaagcg ccgaagccct cgcccacgag
    22141 gccgcacagc agcgcctcca caccgcggtg caggccgcac agcccggcca ggaccggctc
    22201 gccacggcgc ggcgcgcgct cgacagcctg ctcgccgacg atcgcaccga ggcgcgcgtg
    22261 ctgcacccct acgcgcgcgc cctgctcgag cagatccgcg aacggcagca gctcaccttg
    22321 ctcgccgagc gcctgcgccg ccagctcgac gagcgcgcgc actccagcgc cgcgcgcgat
    22381 caggagctcg aggcattgcg ccgacagaac gccgagctgc agcgcaagct ggaggccatc
    22441 gccgacatcg aacgcggcct gagtccgccc acgcccccgg tgcggccccc tgccgggctg
    22501 cccgaatgag cgcgccggcc gccttcgcga ccgcaggcgc tgcgcctgca cgcctgctgg
    22561 tagtcgacga cgacgtcgac ctgctacgtc tgttgtcgat gcgcctgcag gccagcggct
    22621 accacgtcac gaccgccgac ggtgtcgcga ccgcgcgcag ccacctcggc gtggagcgct
    22681 tcgacctcgt gctgagcgac gtccgtctgc ccgacggcga cggcctcgcg ctcttcgagg
    22741 acatccgccg ccagcatccg gcgctgccgg tcatcctgct caccgcgcac ggcagcatcc
    22801 ccgacgcggt cgaggccacc gcgctcggcg tcgccggcta tctcaccaag cccttcgaca
    22861 gccaggccct gctgcggggc atccgccagg cattgcagct cgccggcccg tcccacgccc
    22921 gcgcccgcgc cggcgtgcac gcgcaagccg gcgtcgcccc ccccgccggc gacaccgcct
    22981 ggcgttcagc aatcatcagc cgcagcagcc gcatgcaggc gctcctcgac gaggcccggc
    23041 tggtcgccgt ctccgacgcc agcgtgctga tccgtggcga cagcggcacc ggcaaggaac
    23101 tgctcgcgcg cgcgatccac ctcgccagcc cgcgcgccgc tgcgcccttc gtcgcgatca
    23161 actgcggcgc gatccccgag ccgctgctcg aatccgagct cttcggccat gtgcgcggcg
    23221 ccttcaccgg cgccaccagc gcccatcagg ggctggtgca ggctgcccac ggcggcacgc
    23281 tcttcctcga cgagatcggc gacatgccgc ccgcgctgca ggtaaagctg ctgcgcgtac
    23341 ttcaggagcg cgccgtgcgt cccgtgggcg ccacgcgcgc gcaggcggtc gacctgcgca
    23401 ccgtctccgc cacccatcgc gacctcgacg cagcgctggc cgcggggcag ttccgcgagg
    23461 acctctacta ccgcatcgac gtggtgagcc tgcaactgcc cgccctcgcg gagcgccgcg
    23521 aggacgtccc gctgctcgcc gaacacttcc tgcgccgcct ggcggacaag tacgccaagc
    23581 gcctcaccgg cttcgcgccg gatgcgctgg agacgctcgc caccgccccc tggccgggca
    23641 acgtgcgcca gctccacaac gtggtcgagc aggtgtgcgc gctcgccacc acggcgctga
    23701 tcccgcgcgc cctggtcgag cgcgccctgc gcgtgcagcc ggccgaagcg ctgggctacg
    23761 ccgaggcgaa gcgccgcttc gagcgaaact atctgataca gctgctgaaa ctgactgcgg
    23821 gtaatgtttc ggacgctgca cggctggcgg agcgcaaccg taccgagttc taccgcctgc
    23881 tgcagcgaca cggcctggcg cccgagctct tccgcggcga ccggcccgat gtcgaacaat
    23941 gaacaagaac ctcgaaggag ccggacatga tcaaacgcca gaccatcgcc gccatgctga
    24001 ccaccaccgc gatcgccttc tcgatcgcca ccccggcgca ggccgcccgc ctgctcgaca
    24061 ccgcgcagtt cgacaccgtc gccgcctgca gcggcgacaa gcccgccacc gccaccccgg
    24121 acgagcgcaa ggacaagccc gcgcagacct gatctgcgcg atcacccgtt caatgaaatc
    24181 gaggccgcag cccggatatc gggttcgcgg cttctgccgc tccggcacgg ggcgaaagcg
    24241 accctgttcg cgcctgccgg cgctcctaca ttggtgcagc cgcccggttc gcggcggcag
    24301 aagactgccg tcgagatgcg cccccgcctc aaatcgtccc gccgcccggt tcgcggctgc
    24361 cgccgctcct acacggtggc ggcagccgcg gcggttcgtg taggagcgcc ggcaggcgcg
    24421 aaggctgccg tcgagatgcc ctgcctcagg ccgtcccgcc tacggtcagg ccatcgatgc
    24481 gcagcgtcgg ctggccgacg cccaccggca cgctctggcc gtccttgcca caggtcccca
    24541 cgcccggatc caggcgcatg tcgttgccga tcatgcggat cttggtgagc gcgtcggggc
    24601 cgttgccgat cagggtcgcc cccttcaccg ggcgggtcac cttgccgttc tcgatcaggt
    24661 aggcctcggc ggtcgagaac acgaacttgc ccgaggtgat gtccacctgc ccgccaccga
    24721 agttcaccgc gtacaagccc ttcctgaccg acttgatgat ctcctccggg tccttgtcgc
    24781 cgtcgagcat gtaggtgttg gtcatgcgcg gcagcggcag gtgggcgaag gattcgcggc
    24841 ggccgttgcc ggtgaccggc atgcccatca ggcgcgcgtt catcatgtcc tgcatgtagc
    24901 cggtgaggat gccatcctcg atcagcacgg tgcgctcggt cgggttgccc tcgtcatcga
    24961 tggacagcga gccgcggcga tccggcagcg tgccgtcatc gaccacggtg acgcccctgg
    25021 ccgccacctg ctgcccgatg cgccccgaga aggccgagct gcccttgcgg ttgaagtcgc
    25081 cctcgaggcc atggccgatc gcctcgtgca gcaggatgcc cggccagccc gggccgagca
    25141 cgaccggcat ggtgcccgcc ggcgcggggt cggcaccgag gttcacgcgc gcctgatgca
    25201 ccgcctggcg ggcgtagtcg tgcaggcggt cgtcgcagaa ccagccgtag tcgtagcgcc
    25261 cgccgccgcc ggcgctgccc tgctcgcgac ggccgtcctc ctccatgatc acggtgatcg
    25321 acacgcgcac cagcgggcgc acgtcggcgg cctggtggcc gtcgctgcgc accaccatca
    25381 ccacctccca ggagccggcg atgtgcgcca tcacctgggt gacacgcgga tcctcggcgc
    25441 gcgcgaagct ctccaggcgc tcgagcagct tcaccttggc ggtgtcgtcg agcgaatcga
    25501 gggggtcgtc ggcgcggtac aggcgggtct tgagcttgtg cgggacgatg ccgatgcggc
    25561 ggcgctcacc ggccgcggcg atcgcgcggg tagccgtggc agcaccgacc agggcgtcga
    25621 gcgagatgtc gtcggagtag gcgaaggcgg tcttctcgcc gctgatcgcg cgcacgccca
    25681 cgccctgctc gatgtcgaag ctgccagact tgacgatgcc ctcctccagg ctccaggcct
    25741 cggagcgctg gtactggaag tagaggtcgg caaagtcgat gtcgtgccgc atcagcttgc
    25801 ggaaggtctt ctcgagctcc gcctcgccca ggccgtaggg cgacaggagg taacggtcgg
    25861 cgaccttgag ggggttctgg ctcttgctca tcggtaaatc cttggcggga gatgacggtt
    25921 cgaccgccat cgggcgaaaa cgatcggtgc ggggcgagag gatacgacga cgcgaccaga
    25981 ccccgggcac gcaccgcgtc gggtccgtcg cagcgccggc gttcaggcca ggcagcggtg
    26041 gcgcagcgcg ggcaggctct cgcgtaccgc cgcgagacgc gcgggatcca cgtccgcaac
    26101 caccacgccg gggccttcgt cgcagcaggc gaggatctcg ccccaggggt cgatgatcat
    26161 cgtgtgcccc caggtcaccc gcccgctctc gtggcgccca ccctgggcag gcgccatcag
    26221 gtagcactgg ttctcgatcg cgcgcgcgcg cagcagcacc tcccagtgcg cgcgcccggt
    26281 ggtccaggtg aaggccgccg gcagcacgat caggtcgacc tcgcccatgg cgcggaagag
    26341 ctcggggaag cgcaggtcgt agcacaccga caggccggtg cgtccggccg gcgagtcgaa
    26401 gcaggcgacg gtgctgcccg gctcgatggt ggccgcctcg tcgtagcgct cctcgccgcg
    26461 ctggaagccg aacaggtgga tcttgtcgta gcgcgccacg cggcggccct ggtcgtcgta
    26521 cacgagcgtg ctgttgcgca ccttgtcgtc ggcctcggcg accagcggga cggtgccgcc
    26581 gatcagccac acgccgtggc ggcgcgcctc ggcggcgagg aactcctgca gcggcccggc
    26641 gccctcgggc tcgcggatgc gtaccttggc ggcctcgtcc ttgctgatca gcggaaagta
    26701 ttcgggcaac gcgaccaggc gggcgccggc cgccgcggcc tcggcgatca ggcgggcggc
    26761 gatctccagg ttggcggcga cctcggggcc ggagacggtc tggatggcgg cgatgcgcac
    26821 cggggcaggg agggaggttt cggtcatgtc tgcgagcttg gggcgggtgc cgccacggac
    26881 ggcgaggccc ccgcgggggt tgggcaagga cggggcgcgg cgcgggcgca cgccccgcgg
    26941 tcagcgcgac tccgctgcgg cggccgcgcc gcgcttggcg acctgggggt cggaccacgc
    27001 gccggtcacc gcgtactcga aggcgaagag cttctcgatc gggtcgctga gcagcttctg
    27061 cgcaagatag gtcaccacac cggcgaccgg attcaccagg cccgccgcgg cgccgatcgc
    27121 caccgactcc gccagcgtcg gctgcaccag cacgcgcagg tcctgggtct cggagacgac
    27181 gtcggcactg ccgctcatgg cgatgcgcgc cgccggcccg cggatctcca ggtcctcact
    27241 gcgcagcacg ccgcgggcga ggtcgatgct accggaaatg cggtcgaagg cgaatccttc
    27301 ggagaacacg tcgcggaagt cgagcgtgat ccggcgcggc agcgactgca ggctgaggat
    27361 accgagcagg cgaccgacgc cgggctcgag cttgttgaac tggccggcgc cggtctccag
    27421 gcgcagcctg cccgacaggc tggggtagtc gatcctggtc ggcgccccgc gccaggcgag
    27481 ctggccggcg aggctcgcgg ccccgccgcg caccacgtca gggtagccga ggcgatggat
    27541 cagcgcaccc atcgctgcgg tctccaggct gaagtcgagc tccgtgcgct ggcggatgcc
    27601 tgcgcgccac tgccccctgc cagcgagccg tccatccgca ttttcgagcg cgaagcgatc
    27661 gagctgccag aggctgccgc ggttgcgcgc gaacacctcg aggcggccga gatcgagctc
    27721 gttgatctcg aagcgctcgg ccaccacgtc gagcgcgggc aggcgctgcg gcggatcctc
    27781 cggcggcgcc tcctcggccg caggctcgcc gtcgcccaag gcctgcccgt tgccggcctc
    27841 gcgcaccaga cgcagatggc ggaagcgcgc ggcgagcgtg cccttgcccg ccgcgcgcca
    27901 gtcgaactca ccgtcggcgc gatcgctctc caggcgcgcc ttccacccgc ccggatcggc
    27961 acgggcgcgc aggtcgaccg ccttgaaggt ctggccgaac acgcccagtt cgtcggcggc
    28021 gagcgcgaac tccgccaccg cggcgagcga cccgccggtc gccacgccac cgcccgcgcc
    28081 gctgtcgacc gccggcgcga cacgctccag cactgcgcgc caatcatcga ggtcgagacg
    28141 gtcgagcacc gcagcgaccc gcacgcccgt cgcggaagcg ggcggtgcgt ccgcgctcgc
    28201 tcgtccgagc gcgacgccac catgcagccc tgtgccgtcg ggctggacca gttccgcacg
    28261 caggcggtcg cctaccgtca gcccgatgct cgcaccgctg cccccggatg cacgctcgat
    28321 caccagttgc gctggccagc gctccccggc cgacttgccg aagggctgcg gcaggctgca
    28381 ggcgaaaccg gccaggtcgg aggcgacctc gacccgggtg ccgcgccggc cgacacgaat
    28441 gtcggcagac cactcggcgg tgccggcaag ctcgtcgagc agcggcaggt cccaggctgc
    28501 cgccagcgcc gccgcgtccg cacgtcccgc agcgcggaag cgcaccgcgc cgtcttcgcc
    28561 ggtctgcgcg gagaggcgca gcggattgcc gaacagacgc gcctgcgcct cggagatgct
    28621 cagcgtgtcg gcggtgaagc gcagccgccc gcgcgcggcc tccagcggcg gcagggcctc
    28681 gagcaacgtg agtcgattgt cggtgaagcg gtactcgccc tgcacccggg agtcgatcgt
    28741 gctgcgcaag ggcatcacca gctccagttc gagctcgccg cggccctcgg ccaccatgcc
    28801 atcggtgaag ccgtcgatgc ggcgtgacac cgggctcgcc gacacgaagc gcaggaactc
    28861 ggcggtcggg ccgcgcgcac ggccggtgat ggtcatgatc tcgctcgggc gctggtcgag
    28921 gtcgggcacc tccgccagca catcgaccag ctccactccg aagatccgcc cgcgtggcgc
    28981 gacgatgcgc aggcccggcc cctcgaagcg cacctcgccg tcgatgccct cgattcccgg
    29041 ccagccgggg gcgtagtcga gcgtggcgtc ggcaacctgc acgctgacca ggaagcgccc
    29101 cttgccgtcg cggaaaggga agtcgtcgag cgcgcccttc agttccaggc gtgcgtcggg
    29161 caccttcgcc gcgcggatcc cgctgcgcag ccagttccgc gtgtcctcgt tgaccaccct
    29221 ggggaggtaa cgccacaccg cggtcgcgtc ggcgcgggcg aggcgggcct gcaggtcgat
    29281 ctcgccggcc ccggtggccg ccggccagta gcggcccgcg gcggtgccgg cggcgtcggc
    29341 gttctcgaac gcggcctcgt cgagcacgat cgccaggcgc tcctcctgtc gctgccagcc
    29401 gccgcgcgcg ctcaggcgcg cgaagctcag cgggcccgga tcgaacacct ccggcaggtc
    29461 gagccgcagg gcctcgccgt cgatccggaa gcgtccgctg tcctggtcgc cgtccacgct
    29521 gccggagagc ccggcgaggc cgggcaggcc ctcgcccgcc gccagcccga gctcgtcgaa
    29581 acgtgccgcc agcgtccagc gcgcgggcgc ggtgggttcg ccctgccagg tcaggcgcag
    29641 gtcctcgaca cggccgtgcg gcgcgagcgc cgccaggcgg gtgcgcaatg cggcatcgag
    29701 cggcaggtgg gcggcgagcg cggcgacggt cgcgagctcg agccggtcgg cgacgaggcg
    29761 tccgccggta agctccggcc cgccttcgtc cgtccgctcg gcgcgcccgc gatccctccc
    29821 ctcgccctgc tccagcacca cttcgacatc ggtgggggcg agctcgacgc cctgcgcggt
    29881 ggcgagcgcg aggccgcggc cggcgaaacg cagttcgtgc tccttgcgga cgagctcgat
    29941 gcggccgtcc agccgggcca gctcgagcgc cggcagcgcc tcgccaaacc gcgcacgtgc
    30001 accgtcgagc gcgaggtccg cgctcagcgc gtggccgtcg cggccgtcgg cgtccaccca
    30061 ggctcgcagc gtgccttcgc cttccaggcc gaagggcaga tccacccagg gccgccagtt
    30121 gccgagcggc gctcgcccga tctcgaggta gagccggccg gcgaagcgtt gcggctgcag
    30181 cgggtcgatg cgacgtagct cgccgcgcac gctcacgcgc tcgccaaggc cgggtggcag
    30241 ccgcgcctcg agcgcgaagc gcgccgggcg tgcacgccgg tcgaggcgga actccacctc
    30301 ctcgagctcg agcggcaccg cgccgcgcgc ctcgtccgcc caggccaggc gtgcgccgtg
    30361 gatgcggatc tggcgttgcg cgagcagcca gccgaggccg ccgtcgcctg gcgcgtcacc
    30421 cggcgcaagt tcgatgcccg cgacgtgcag ccctcccgcc gcatcgcgcc gcaccagcag
    30481 gtcgggcgcg cggatctcga ggcggtgaaa gtgcggctcc agcatcgcca gcgacgacca
    30541 cgcgagggtg gcgtcgacct cgggcagggt cagcgtcttg cggccgtgca catcggccag
    30601 gctcacgccg gtcaggcgca ggcgtggccg ccagcccgcc cagcccccct cgatgcgctc
    30661 gatcgccacc gccacgccga ggcgctcgcc gagcagtccg gcgatcggtg cgcggaagtc
    30721 acccaccgcc ggcagcacga catggcgcag caccagcacg ccggcggcga gcacgcacca
    30781 gacgagcagc agcatgtcga acaggcggcc ggcggcagtc cgccagcccg cgcgcacggc
    30841 gggcgggaag atggcttcga caggtgcggg cggggtggag gagctcagtc gggtgctcgc
    30901 aagacgttgc gcgcaagcgc ggttgcggcg ctgccggcgc agcacgcggg cagctagaat
    30961 gccggaattg cgtccgctcc cgccggatcg ccggagcgcg cgcattctac caagtctcga
    31021 ccgcgctctc gcgccgcatt ggagtccttc atgtccgccc cgaacagcgt tcccgccccc
    31081 gcccttccgc ccgcggtggc gcaggcgcgc cgcctgtcgc gctacctgtc gcgcatgctc
    31141 gacagccagc cctggctggc cgaggcgctt gccgccagca tcgagcgccc gctcgccgag
    31201 gccgacctgc agcgcttcgt ggccgcgcgc gaggtcctcc acggcggcgg cgacggcgcg
    31261 ctgcgcccgg cgctgcgcca gttgcgcatc tggacgctgt gccacctgat cgtgcgcgac
    31321 ctcgcgctcg ccgccccgct cgccgagatc accgagacca tgaccgtgct cgccgaggtg
    31381 gcgctgcgcc acgcccacga cgtgctgcgt ggcgcgctcg tcgagcgcta cggccagccg
    31441 ctctcgccta ccggctggga gcaggagctc ctcgtggtcg gcatgggcaa gctcggcggg
    31501 cgcgagctca acgtgtcctc cgacatcgac ctgatcttca tctaccccga ggacggcgac
    31561 accggcgggc gcaagtcgat cagcaactac gagttcttcg agaggctcgg caagcagctg
    31621 atccaggcac tcgccgaaat caccgagcac ggccaggtct tccgtgtgga catgcgcctg
    31681 cgccccaacg gcgactccgg cccgctggtg tgctgcttcg acatgctgga gaactacttc
    31741 gtcacccagg gccgcgagtg ggagcgctac gcctggatca aggcgcgggt gatgctgggc
    31801 gagcgctggc cggagctcga gcagctcgcg cgccccttcg tgttccgcaa gtacctcgac
    31861 ttcggcgcga tcaacgcgat gcgcgagttg cacgcgcaga tccgccgcga ggtcgcccgc
    31921 cgcgagcgcg ccaacaacgt caagctcggc cccggcggca tccgcgagat cgagttcatc
    31981 gcccaggtct tccagctcat ccgcggcggg cgcgacaccg cattgcaggt gcggcccacg
    32041 ctcaaggtgc tcgcgctgct gcccgagcgc ggcatcctgt ccgaggaggc ggtgacggag
    32101 ctgtcggacg cctacgtctt cctgcgccgg ctcgagcacc gcctgcaata cctcgacgac
    32161 gcccagaccc acgacctgcc ggagaaggac gcggaccgcg cgttgatcgc cgaggccatg
    32221 ggcttcgccg actacgcggc gctgctcgcc gtgctcgacg cccaccgcga ggtggtgagc
    32281 cggcacttcg acagcgtgtt cggcgacccc tccgaggagg accacagcct cgacgccacc
    32341 tgggccaacg cgcgcgacac cgaggccgcc accaacgcgc tcggcgagct cggctaccgc
    32401 cacccgcgcg ccgccgccga gcgcctcgcc gcgatgcacg ccagcccgcg ctaccgccag
    32461 ctccccaaca acatcaagag ccgcttcgac gccctcatgc cgcgcgtgct cgaggccgcc
    32521 gccggcacgc cgggcgcgga cgaaacgctc gcgcgcatgc tcgacctcgt cgatgcgatc
    32581 ggccgccgcg gcgcctatct cgcgctgctg cagcagtacc cgcaggcgct gcgccgcgtg
    32641 gccgacctga tgagcgcctc gcgctggggg gcgcaattcc tcacccgcca cccgatcctg
    32701 ctcgacgaga tgctcgacgc gcgcagcctc gacaacgccc ccgactggaa gaccttccgc
    32761 gtcagcctca gcgaggagct ggaggcgctc gaacccgaca tggagcgcca gatggacatg
    32821 atgcgcgagc gccatcacgc ccaggtcttc cgcctgctca cccaggatct cgccggactg
    32881 ctcacggtgg agaagctcgc cgaccacctc tccgagctcg ccgacctcgt gctcgacctc
    32941 accctgccgc tgtgctggcg ccgcatcaag atccgccact gcgaggagcc gaggttcgcg
    33001 gtgatcagct acggcaagct cggcggcaag gagctcggct acgcctccga cctcgacatc
    33061 gtcttcctct acgacgacga ggccctggag gcgcccgagg tctatacgcg actcgcgcag
    33121 cgcgtcagca cctggctgtc gagccagacc gccgccggcc agctcttcga gaccgacctg
    33181 cgcctgcgcc cgaacgggga atccggcctg ctggtgagct cgctcgagtc cttccgcagc
    33241 taccagcgcg agtcggcctg ggtgtgggag caccaggcgc tcacccgggc gcgcttctcg
    33301 gccggcgacc gcgcgatcgg cgaggccttc gagcgcatcc gcagcgaggt gctgtgcatg
    33361 cggcgcgatc tggacagcct gcgcgccgag gtgctggcga tgcggcacaa gatgcgcgac
    33421 gcgcacggca gcaagagcga ggaggtgttc gacctcaagc acgacacggg cggactgatc
    33481 gacgtcgagt tcctgatcca gtacctcgtg ctcggccaca gccacgacca cccgcgcctc
    33541 accggcaacc tcggcaacat cgcgctgctg cgcatcgccg gcaagctcgg cctgatcccc
    33601 gccgagctgg ccgccgcctg cgccgacagc taccgcgagc tgcgccgcct gcagcaccgt
    33661 cagcgtctca acgagcggcc ctcgcgcgta gaccccgccg aggccgccgc agcgcgcgag
    33721 ccggtgcgcg cgctgtggcg ggccgtattt ggggaatagg cggcgcggca gcgatagccg
    33781 gcggcgcatg agcagacgcc gccttcgcgc ctgccggcac tcctacatga accatcgcgc
    33841 ggccccaagg cacgggcgcc ggatgcggcg acggtctctg taggagctgc ggcagctgcg
    33901 aacccggcga cccggcaagc gacgcgcgtg caggactcca ccgccgcttt cgcgcctgcc
    33961 ggcgctccta catgaaccat cgcgcgcccc taaggcacgg gcggcggatg cggcgaccgt
    34021 ctctgtaggc gctgcggcag ctgcgaacag ggcggtccga caatcgacgc gcgtacgctt
    34081 ctccaccgcc gctttcgcgc ctgccggcgc tcctacatca accgccgcgc gtcccggccc
    34141 tcctgtagga gctgcggcag ctgcgaagag ggcggtgcag cgcccgccgt cggcgtggtc
    34201 gtgtgatggc gaggctgtgt tcgcgcctgc cggcgctcct acggaaaccg ctggcaccct
    34261 gcaggagcgg cggcgggcgc gagccgggcg gtgcggacat cgtaggcgcg gtgaaatatt
    34321 tcacgtcgca aaagcgtgca tgacgccccg cgggccggcg tctagaattc aggcgccctg
    34381 tcttccagcg cccgcccgcg ggcgacatcc atgagccacg agatcgaact caagctcgcg
    34441 ctgcccaagc gcgcgctccc cgcgctgcgc cgccacccgc tggtagccgc ggcggagaaa
    34501 tgcggcaacg ccctcaccct cgacaacacc tacttcgaca ccccgaagct gcagctcaag
    34561 gcgcgcaagg tggcggtgcg cacccgccgc cagggccgcc agatgctgca gacggtgaaa
    34621 tgcgcggcgg tgtcgagcgg cgggctgtcg cagcgcccgg agtgggaaac cgcgtggacc
    34681 ggcgacttcg atttctcccc ggtcgacgac cccgccaccg cgcgcctgct cgaacgccac
    34741 cgcgacgagc tggtgccggt gttcaccacc cgcttccgcc gcgagacgcg gcgcctcgtg
    34801 ccgcaggagg gcgtgtccat cctgctgatg atcgacaccg gcgcggtgca cgtgcgcacc
    34861 ccggagggcg tcgagcgcga ggccgagatc tgcgagctcg agctggagct cgagagcggg
    34921 cgcgcgcagg acctgctcga ccttgcctgc gcgctcgcgc aggacctgcc gctgatgccc
    34981 gccgacctct ccaaggccga gcgcggctac cgccttttcc tcgacacccc ggccggcgcg
    35041 ctgcgcgccg aggcgtccac gctcgagccc ggccacaacg tggtggaggc ctttcgcacc
    35101 ctggcgctgt cctgcgtgcg ccagtggcag ggcaacgccg cgaccgcgct cgcgcaaggc
    35161 gaccccgacg cgatcgatcc cgacaacatc caccagctgc gcgtcgccca ccgccgcctg
    35221 cgcgcgctgc tgaagatctt cgcccctgcg ctgccggaga ccttcgccgg cacctggaac
    35281 gcgcgcctgc gcgacaacgc gaaccgcttc ggcgatgcgc gcgacctcga cgtcttccac
    35341 gccgagctgc tcgagccggt gacgcccgag ggcctggccg acgcggcctc gatggcggcc
    35401 ctgctcgaga ccgtgcgtgc agcgcgtgcc gccgcccggc atcacgccgg cgtcagcctc
    35461 gacctcgcca cccagggccg gctgctgctg gagttcaccg ccgcactgca ccgcctgcgc
    35521 gcagacagcc tcgccgaggc cgccgacctg cgcagcttcg cccgcctgcg cctggaccgg
    35581 ctgcgcaagc gcgcgcgccg tggcgcccag gccgcggcca gcctggagcc cacccgcctg
    35641 cacgcgctgc gcatcgactt caagctgctg cgctacggcg tcgagttctt cgcgccgctg
    35701 ttcggcgcca agggcatcgc gcgctacctt gacggtctgg tgcgcgcgca gaccacgctc
    35761 ggcttcctgc aggacgtcga cagcgccctg cagcgcctcg ccgagtggtc gcgcacgcag
    35821 ccggaggtcg cgcctgcggc ggccttcgtg ctgggctggc atgcgccgcg ctacgcgcgc
    35881 ctgcgccggc gcgtgctgcg cgaaagcgag ccgctgctgt ggggcgacaa gccgtggtga
    35941 ggcgggccgc cccaccggcc gcgcggcagg ccgccgtcat cgtgctgtaa ccgccgcatc
    36001 cgatgatgcg cgccctcgaa ccccggacga acgacatgga cctgctgctc tggcgtcatg
    36061 cggaagcggt ggacggcagc cccgaccaca cgcgcgaact caccccccgc ggtctcaagc
    36121 aggcgcgtcg catggcgcgc tggctggaag acaaccgtcc caagaacctg aaggtgctgg
    36181 tcagccccac gctgcgcacc cgccagaccg cgaccgcctt caccgacgag ttcgagatcg
    36241 tcagcagcct ggggccggag ggcaacgtcg ccgacatcct cgccgccacc ggctggcccg
    36301 agggcaacgg cgccgccctc gtggtcggcc accagcccgc cctcggccgc ctgtgcgcgc
    36361 tgctgctgtc gggcagcgag gccgactgga cgatcaagaa gggcgcgctg tggtggttca
    36421 ccaaccgcgt gcgcgagggc gagacgcaga cggtgctgcg cgcggtgatc ccgagcgagc
    36481 tggcgtgagg ggtgaagagt aaggcgtcag gcgtcaggcg cacctggctc ctcacgcctc
    36541 gcgcctcacc cctcacgccc cattgaattc cttgccgcga gcgcggtcga aaccggctga
    36601 agaacctccc ggacggcagg ctcgcgcacg gtcctagaag gccgtgacgg gctcgcttgt
    36661 gctttgccat gcaatgcgta agatgccgtc ttccttccgg accggaccat gttcgaacgc
    36721 ttcctgccca ctcgcgaagc catcacgcaa agccgcatgc tgcgctggct cggaccgcgc
    36781 ctgcacgatc cgctgctgtg gcatgtgaac cggcgctcgg tggcacgcgg cgtggcgatg
    36841 ggcgtgttct tcggcctgat gatcccgatc gcgcagatcc ctgcggcggc gatcgcctcg
    36901 ctgctgctgc gcggcaacct gctgatcgcc gcgatctcca cgctggtgag caatccgctc
    36961 acctacggcc cgctctatta cttcgcctac cagctcggcg cgggcgtgat cggcacccgc
    37021 acgccgatcg acctcacgcc cgccgacgtc gaggcgccgg tgcgcgcgat cgactcgctc
    37081 gcccaggcct ggacgtgggt cagcggcatc ggccagccgc tgctggtcgg catggtgatc
    37141 atggcggtga cgggctcgat catcgcctat tggggcacgc agctgttctg gcggctgcgc
    37201 gtggctgccc gccgccgtcg ccagcgccgc gagcgcagcg cgcgcgcctc cacgcgggct
    37261 attggaagcg cctgagcacg ggcgtatcct tcgcatcccc caacggctca acggacggcc
    37321 acggccatgg aagactccat ccccgacggt acggtcgcga tcatcgacgg tgtacgccgc
    37381 atccactacg acggctactg gctcaaggcc tacgaaccgc cggcggatac cctcgacgcc
    37441 aagaagcggc tgatccaggc cctcacgcgg cgcctgttca accacgtcga gcacggcatc
    37501 aacatcccgg gcaagcgcct cgacgacgcg cgccgcgcct acgaggccga ggacgacccc
    37561 gcgcgcaagc gggtcaaggg cgcaatgtat gcgggcgcgc tgttcaaccg cgccaccgac
    37621 atcttcacca agctggtgga gctgcaggaa ctgggcatcg agatcgccac cgacaacccg
    37681 ctgatgcgcg agtgcggcgg ctgcctgcag gaggcgctca agctcggccg cctggtgttg
    37741 caccgcagcg gtgacgaggg catcgacgag ctgtggggcg aacccttccg cgccttctcg
    37801 atcccggtgg aggccttcta cgaaagccgc tacatcaaga tcgcgcaggc gctgcgcgag
    37861 gtggaccgca tcgcggcggt gatggccgcc accttcgcca cgacgccgct gttccgcggc
    37921 gtggagccgc tggtgttcga cttcgcgcgc atcgccaaga tcaagtgcga gaccctgcgc
    37981 accgacccgg acatcttcga cgtgtgggcg gagttcgtca ccgcctcgga gcgcctcgcc
    38041 gcgctgtcgc cggcgctcgg cccgggcgcc gacgagtgca cccgccagct ggccgcggat
    38101 ggcctgcacc tgatcctgca ggggcgcaac ctggtcaccg acatcatccg cgcgcgcgtg
    38161 accatgccga agagcgcgcg agagttcatc gagcgctgcg agaccttcgc ggcgcgcgcg
    38221 caggcagcct cgcatccccc gctcgccgcc gccgacctag gcgcgacgcg ggcgtagggc
    38281 aggcgtgcgg ccggagccgc ctcacgcctc acgcctcacg cctcacgcct cacgcctgca
    38341 ggatgattcc cccgcccagg cagaccttgg actcgtacac caccacgctc tgccccggcg
    38401 tcaccgccca ctgcggctgg gcgaaggcga tctcggcgcg gccttcggcg atgcggtcga
    38461 tctcgcaggg ctggtcggga gtgcggtagc gcggcttggc ggtatacacc cagttggtgt
    38521 gcgggtcgcg cccggcgatc cagttgaggt cgccggcgac caggcggtcc ttcagcagcg
    38581 ccgggtgggc gtggccctgg accacgtaga gcacgttggc cttgacgtcc ttgccggcca
    38641 cgtaccaggc gtcgtgctcg ccggcctcgt cctggttgcc cttgaggccg ccgatgtgca
    38701 ggcccttcct ctgcccgatg gtgtgataca tcaggccctg gtgctcgccc agcacgcgac
    38761 cgtcgtcgag cgcacggatc tcgcccggcc gggtcggcag gtagcgcatc aggaattcgc
    38821 ggaaggggcg ctcgccgatg aagcagatcc cggtcgagtc cttcttctcg gccacgtgca
    38881 ggccggcctc ggcggcgatc ctgcgcacct cgcgcttgta cagcgtgccg agcgggaaca
    38941 tcgtcttcgc gagctgctcc tgggtgagac ggtagaggaa gtagctctgg tccttggtgc
    39001 cgtcctcggc cttgagcagc tggtactcgg tgcgaccgtc gttggtccat gggcgcacct
    39061 gggcgtagtg gccggtggcg atgcgctcgg cgccgagctg catggcgtgg tcgaggaagc
    39121 agcggaactt gatctcggag ttgcacagca cgtccgggtt gggcgtgcgc ccggcctcgt
    39181 actcgcgaag gaagtcggcg aacacgcggt ccttgtattc ggcgctgaag ttgacgacct
    39241 cgaggtcgat gccgatcacg tcgcacaccg aggccacgtc gaccagatcc tgccgcgtcg
    39301 agcagtactc ggaatcgtcg tcgtcctccc agttcttcat gaacaacccg gtgacctggt
    39361 agccctggcg cttgagcagc agcgccgtga ccgccgagtc caccccgccg gacatgccga
    39421 ccaccacctt catccccgca ccgtcctgct ttccatcccg actactggac attcggtcca
    39481 cctccattga gccattccgc gagcggcagc acgacggccg gctcgccatt gtcgacgaac
    39541 cagctgtcga ccacgtaacg ttgtcccgga cggtcgtcgc cgtccgcctc cccaatgccg
    39601 ccgatcacca gcccgtcctc ggtgcagttg cagcccgcca gcgcctggcc gggcggcagg
    39661 cgatcgatgc gctccgccac cgacaacacc tcgatcaccg cgctgaagtg ctgcaggatc
    39721 agtcgggtac ggcgcgccgg ctcgacgacg cggtggaagc gcagcgcgcc gcgcgcctcg
    39781 agcagctgca gcagccgagt ggtggaggtc gaatgatcga tgcagtccat gcgtccgtcc
    39841 gcgcccccgt cgagcaggtt gccggcgcga tcggccgcga ccgcggtctg cgtcgccgcc
    39901 acgcgataaa gcccgcccac cgccccggcg aggcgttcgc gctcttccgc ggcattgcgg
    39961 gcggcggcga ggcgttcgcc gatccggcgc agcgtcgggc cgcgcacatg gacgctaccc
    40021 tcgctcgcgc agccgtagtt gtagcagatg ctgagccggg ctccgccgtc ggcgccttcc
    40081 ggacccgccg tcgcccacgt cgccgccggc agggcaagca gcgcggacaa cagcaggcag
    40141 ggcaggcgcg ccgacattcc gttcagcagt gatgcaccag cgcgagcggg tggcgctgcc
    40201 cggcgatcca gtcctcgatg cactgcagga tcagcgggct gcggtgccga tcggcgcacg
    40261 cgcgcacctc gtccagcgtc agccacaccg cgcgcacgat gccctcgtcc agcctgcgcc
    40321 cgggctcctc gccgcgcaga cggccgccgt aggcgaagcg caggtaggtg atgtcgccct
    40381 gcggccgcgt ccactggtag atgccgacga ggtattcggg ctcgaagtgg tgggcggtct
    40441 cctcgagcac ctcgcgcacc gtggcctgca gcagcgactc gccctcctcg aggtggccgg
    40501 cgggctggtt gaagcacagc ccctcgggcg tctcctcctc gacgagcagg aagcggccgt
    40561 cgcgctcgat gacggcggcg acggtgacgt tgggtttcca gggacgatcc ttcactccga
    40621 tgctccaggc gcatgaaggc ccgcattcta gcgcgccccg gcggagggcg gcgcgggtcc
    40681 cgccggcggg gtgccggcaa cggcccgcgc ggcgtgcgtg cgcgcctgca tcgcgagggc
    40741 ggctttacgc tagaattgca aggctttgcg cccggagaac ggagagggcg cgcgacgaac
    40801 ccattcagcg tacctatttc aaggcggaga tcttcatcat gtccatggct gaccgcgacg
    40861 gcttcatctg gcaggacggc aagctcgttc cgtggcgcga ggcgaccacc cacgtcctca
    40921 cccactcgct gcactacggc ctcgccgtgt tcgagggcgt ccgggcctac aacaccgtca
    40981 gcggcaccgc gatcttccgc ctcgccgagc acacccagcg gctgatcaac tccggcaaga
    41041 tctacatgat ggacatcccc tactccaggg atgaactcat ggaggcgcag aaggaggtcg
    41101 tgcgcgcgaa caagctcgag tcgtgctacc tgcgcccgat cgccttctac ggatcggaaa
    41161 agatgggtat ctccaccatc ggcgccaccg tgcatgtggc catcgccgcc tggccgtggg
    41221 gcgcctacct cggcgaggag ggcctgcaga agggcatccg cgtgaagacc tcgtccttca
    41281 cgcgccacca tgtcaactcg acgatgccgc gcgccaagct ggccgcgacc tacccgaact
    41341 cgatcctcgc caacctcgaa gtcacccgca tgggctacga cgaggcgctg ctgctcgaca
    41401 accagggctt cgtcgccgag ggcgcgggcg agaacctctt catcgtcaag gacggccgca
    41461 tctacgagcc cgagatcgcc tcggcgctga ccggcatcac ccgtgactcg atccacgtca
    41521 tcgcgcgcga gctcggctac gagatcggca ccaagcgcct gacccgcgac gacatctacc
    41581 tcgccgacga ggccttcttc accggcaccg ccgccgaggt cacgccgatc cgcgagctcg
    41641 acgaccgcaa gatcggcgag ggcaagcgcg gcccgatcac cgagaagatc cagggccgct
    41701 tcttcgacgt ggtcaacggc cgcgcgccgg aatacgccca ctggcttgca cacgtctgat
    41761 ctccacgctc cgaggataac gtcatggttg aaaacaccga caagacccag gccgtcgtca
    41821 ccaccgccaa ggacctgccg ctgcactgcc cgccgccggg cgcgccgctg tgggcccgcc
    41881 acccgcgcgt gttcctcgac atcctgaaga ccggcgaagc cgtctgcccg tactgcagcg
    41941 cgcactacgt gttcaacggc gagcgcccca agggtcatca ctgagaaaga agccggagac
    42001 cgggcctccc cggcccgcgt cccgaccgga ccacgggggc ttcggccccc gtggtctttc
    42061 agatccacca acaataaaaa caccgccttg agcagacctg tcttcaccac cgccctcgaa
    42121 gcggaagccg ctttctaccg cgccctcgcc gagggcgact tcgaggccct gatggccgtc
    42181 tggtcggaag atgaggaggt cgtctgcgtg cagccgggtg gcccgcgcat cgtcggcctg
    42241 cccgcggtgc gcgagatctg gcggcagatc ctcgccgacg gcgcacgcat ccgcatcgac
    42301 gtcaaccatg cagtggccag ctccaccgcg atgatggcga tgcactgcgt gctcgagcgc
    42361 ctcgccaccg acgggcccac cccgcgcacc gcgacgatcg ccgcgaccaa cgtgttcgtg
    42421 cgcggcgccg acggctggcg catggtgctc caccacgcct cgccggtacc cgagatgtcg
    42481 gggccggagg attcgacgcc acgcgtgctg cactgagccc gcccgacccg gagccgtcca
    42541 tgcgccacac cctgcccgcc gccgagctct tcaaggccta cgacatccgc ggcatcgtcg
    42601 acacggtgtt gacccccgcg gcggtgcgtg cgatcggcca cgcggtcggc tccgaggcgg
    42661 tggcgcgcgg ccagcgcgcg atcgcggtgg gacgcgacgg ccgcctgtcc agcccggcgc
    42721 tcgccggcgc gctgaccgag ggcatccgcg ccgccggcat cgatgtgatc gacctcggct
    42781 gcgtgcccac cccgctcacc tacttcgccg ccttcgagct cggctgcggc tcctgcgtgt
    42841 cggtcaccgg cagccacaac ccgcccggct acaacggcct caagatcgtg ctcggcggcc
    42901 acaccctgca cggcgaggcg atccaggacc tgcgccggcg catcgccgcg gacgacctcg
    42961 tcgacggcgc cggtgcgctg cgcagcgccg atgtgcgcgc cgcctacctc gaccgcatcg
    43021 tcggcgacgt caggctcgcg cgtccgctga agatcgtgct cgactgcggc aacggcgtcg
    43081 ccggcgccat cgcgcccgag ctcttccgcc gcctgggctg cgagctcgtc gagctgttct
    43141 gcgaggtcga cggccgcttt cccaaccacc accccgaccc ctcccgaccg gagaacctgc
    43201 gcgacgtgat ccgcgcgctg cgcgagaccg acgccgagct ggggctggcc ttcgacggcg
    43261 acggcgaccg cctcggcgtg gtgtgcaagg acggcgagat catccacccc gaccgccagc
    43321 tcatgctctt cgccgccgac gtgctctccc gcgtgccggg cggcgagatc ctctacgacg
    43381 tcaaatgcac gcgcaggctg gcaccgtggg tgcgcgcgca cggcggccgg ccgacgatgt
    43441 ggaagaccgg ccacgcgctg ctcaaggcca ggctgcagga gaccggcgcc gcgctcgccg
    43501 gcgagatgag cggccacatg ttcttccagg aacgctggta cggcttcgac gacggcctct
    43561 acgcgggcgc ccgcctgctc gagatcctct ccgcccgcgc cgacgccaac accgtgctga
    43621 aggcgctccc cgattcgaca agcacaccgg agctgaatct ggagatgcgc gagggcgagc
    43681 ccttcgagct ggtgcgccgg ctgcgcgagg ctgcgctcgc cagcccttcg tgctttgccg
    43741 acgcgcgcga ggtgatcacg ctcgacggcc tgcgggtgga gttcgcccac ggcttcggcc
    43801 tcgcccgcgc ctcgaacacg acgccgatgg tggtgctgcg cttcgaggcc gacgacgccg
    43861 cggcgctggc cgagatcgag gcggcgttcc ggcgcgcgct cgacgcggcc tggcccgggc
    43921 tcgcgctgcc gttctgaagc ctcggcgtag cggcgtcgcg aaagccgacc agccccccgc
    43981 ggcgctatct cgtgaggcgc agcgcccgaa aacctcgcaa ccggcagggg aatgcgaaaa
    44041 aatgcacgcc acctgcatcc gtggcggcgc acaatccgta aattgttttt atccagtcca
    44101 aggcgagcga ggcagtccat gacggcacgg gaacggcgcg aagcacgcgc acgcgacagc
    44161 aagcaggccc acaagggcat cgacatccca tcctgccccg gcatcctcgc ccagctcatg
    44221 gacgaactgc gccagccgca ggtcagcggc aagcgcatcg ccgccctgat cgggcaggac
    44281 gtcgggctcg ccgcggtcgt ggtgcgctcg gccaattcgc cctacttcgg cagcgggcga
    44341 cggatcgcct cgatcgacga cgcgatccgc atgctcggct tcggcatgct cgccaacctc
    44401 gtccacgagg cccttctgcg cagcagcatc gccgaccccg gcgccgcgct cgagcgcttc
    44461 tgggacagct cgcgctgcac cgcgcaggcg agcgcgatgc tcgcccgccg caccggcatc
    44521 gcacgccccg agaccgccta caccttcggc ctcttccacg actgcggcat cccgctgctg
    44581 gtcaagcgct tccccgacta caagcgcatc ctgggcacgg ccaaccaggc caccgggcgc
    44641 tggttcaccg acgtagagga cgaggcgctc gacactaacc acgccaccat cggctacctg
    44701 ctcgcgcgct cctggggcct caccgacgcg gtatgcaccg gcatcctgtg ccatcacgac
    44761 tactcggtgt tctcccccga ctccggcctg gaggtcgagg cgcagaccct gatcgcgctc
    44821 aacctggtgg ccgagcacgt cgccggcacc cacctgcgca cccggcgcga cgccgaatgg
    44881 gacaagggac gcgaggcggt ggcgcgctac ctcggctacg cgccgaccga gctcgacgac
    44941 ctcgccgacg acctgctcta cgcgctggac cggcagggcg aagacctccc ggcctgagcg
    45001 ccgcgcgggc gcttcgccgc ccgcgcgcgc acgcccgtca caccggctcg agcctcgcca
    45061 cgccgagcag cagccacttg accccggcgg ggccgaagtt gatctgcacc ttggcgtcgc
    45121 tgccgctgcc ctcggcggcg acgatcaccc cctggccgaa cttcgcgtgc gccaccgcct
    45181 ggccgatgcg caggccaccg ggcagcgtgg cgaaggacgg acgcggcgcg cgcggcacct
    45241 gcggcgtgcc gcccacggcg gacttggccg agggcttgaa gtagcccccg cccatgccgc
    45301 ccatcgcgcc accggcggcc gcacgcgggc tgggcggggt cagccacttg gtcagccctg
    45361 cggggacctc ctccaggaag cgcgagcgca ggttgtagcg cgtctgcccg tgcagcatgc
    45421 ggctctgcgc gaaactcagg tacaggcgcg cgcgcgcgcg cgtcaccgcc acatacatga
    45481 ggcggcgctc ctcctccagc ccgtcctgct cgaggatgct gttctcgtgc gggaacagtc
    45541 cctcctccag tccggacagg aagaccacgt cgaactcgag ccccttggcg gcgtgcacgg
    45601 tcatcagctg caccgcgtcc gcaccctggt cggcctggtg gtcgcccgcc tcgagcgagg
    45661 cgtgggcgag gaagtccgcg agcagcgcat gcggctgcgc cagggcctcg ccggcacccg
    45721 actgggcctg cgcctcggcg aggaagttgg ccgcggcgtt gatgagctcg tcgaggttct
    45781 ccaggcgctc acggccttcc ctgtcggcct tgtagtgcgc gcgcaggccg ctcaggtcga
    45841 gcacgtgatc caccagctcg ggcagcggca ggccggcagt gtcgcggcgc aggtcctcga
    45901 ccaggcgcac gaagaccgcg agcgcgctcc cgggcttgcc ggacagatgc ggcacggtgg
    45961 cgtagaggct ggtgttatag gtgcgcgccg catcggtgag cacctcgagc gagcgcgcgc
    46021 cgatgccgcg ggtgggaaag ttcaccacgc gcgcgaacga ggtgtcgtcg tccgggttgg
    46081 cgatcaggcg caggtaggcg agcgcgtgct tgatctcctg gcgctcgaag aagcgcagcc
    46141 cgccatacac gcggtagggg atcccggccg cgaagagctg gtgctcgagc acgcgcgact
    46201 gcgcgttgga gcggtagagc agcgcgatct cgctgcgcag cccgccgtcg cgcaccaggg
    46261 cctggatctc ctcgacgatc cagcgcgcct cgtcggcgtc ggcataggcc tcgaagacgc
    46321 ggatcggctc gcccgcgccc tggtcggtcc acaggttctt gccgaggcgg ttgctgttgt
    46381 gaaggatgat cgcgttggcg gcgtcgagga tgttggcgtg cgagcggtag ttctgctcga
    46441 ggcggatcac gttgctcacc cggaactcgc gctcgaagtc gcgcatgttg ccgacctcgg
    46501 cgccgcggaa gcggtagatg ctctggtcgt cgtcgccgac gcagaacatc gccgcgccgc
    46561 cctcgcggcc ctcgtcggcg aagagcttca gccagcggta ctgcaggcgg ttggtgtcct
    46621 ggaactcgtc gaccaggatg tggcggaagc ggcgctggta gtggcggcgc agcggttcat
    46681 tgcgctcgag cagctcgtag ctgcgcagca gcaactccgc aaaatccaca acagactcgc
    46741 gctggcactg cgcctcatac tcttggtaaa gctgcacgcg caggcgggtg tagtcgtccc
    46801 aggcctcgac cgcatgcggg cggtgaccgg cttccttctg gccgttgatg aagtgctgga
    46861 gttcgcgcgg ggggaatttc tcgtcgtcga cgttcagggt cttcagcagg cgcttgatcg
    46921 ctgcgagctg gtcggccgag tcgaggatct ggaacagctg cgggagtccg gcgtcgcggt
    46981 ggtgggcgcg cagcaggcgg ttggagaggc cgtggaaggt gccgatccac atgccgcggg
    47041 tgctcaccgg cagcatcgcg ccgaggcggg cgagcatttc cttggcggct ttgttggtga
    47101 atgtaaccgc gaggatgccg gccgggtcga cctggccgga ctggatcagc caggcgatgc
    47161 gggtggtgag cacccgcgtc ttgcccgatc cggccccggc caggatcagg gcgtgctgcg
    47221 cgggcaggct caccgcctgc agttgttcgg ggttcaggtt gctcagcagg gtggacatcg
    47281 cgtttcctct tcgagccggc attgtatcgg ccccgagcga cgaggccgat acgacggacc
    47341 gggcgaaccg gagagaaaga gacacaacat gatgttgcgt cgcaacaaca tcgcacttgc
    47401 agctttcctc agttgcgcta aatttgagtt gtgcactgca ccaaatccct ccgatccgcg
    47461 gaaccttttc acggaaattc tggtcggaat tgtgcagaat caaggaacta acccgggcgc
    47521 ccggctatta ttgcgccaca acattttttt ataaggccgc cgcccagaaa gtggttgccg
    47581 aaacgagggc catatccggc cccgatggag aacgcatcat gaaaacgccc aagctgctgc
    47641 cctggtatgc ccgcaaagcg ggcgtctcga tcgagcgcgc cgaaaccctg tggcgcaagg
    47701 ccgtgcgcga agccaccgcc gaaaccggct gggtcggcaa cgccgaatac tggggcgcgg
    47761 ccatggacca ctttgtccgc ctgctcgatg aagagcgcag cacgctgtgc gcgccgcgcg
    47821 tgcagtccta cgtccgcagc cagaaccgca tgtggcggct gccgctgatc gccatggaag
    47881 acctgttctc ggccttccac gcgagctggc agcgccagca cggcgccgac caccgccgcg
    47941 cggcctgagc gccaccacat ccagaatccc acgcgccgct caggtggcgc ggacacgctt
    48001 gcttgtctcc ctccctcctt caatggagat tcggcgctct gcccacgcgg agcgccattt
    48061 ttttgcctgc tccaccgctg tctgcgcagc acgcaggcct gctggcgagc acggcgggta
    48121 acagcccgac cccaccgcgg cccccgtcgg gagcgcccgg caccgcgctt cgcggtatac
    48181 tggcgtgttt tcaacgccat ccagcccgcg cgcccgccat gcaggaaaaa taccagcccg
    48241 ccgccctcga gacggccgcc cagcagcact gggactccac cgacgccttc cgcgtgaccg
    48301 aggacgccgg ccgtccgaag tactactgcc tgtcgatgtt cccctacccc tcgggcaagc
    48361 tgcacatggg gcacgtgcgc aactacacca tcggcgacgt gctcgcgcgc ttccaccgca
    48421 tgaagggctt caacgtgctg cagccgatgg gctgggacgc cttcggcatg ccggccgaga
    48481 acgccgcgat ccagaacaac gtgccgccgg cgaagtggac ctacgccaac atcgactaca
    48541 tgaaggcgca actcaagcgc ctcggcttcg ccatcgactg gtcgcgcgag ctcgccacct
    48601 gcacccccga gtactaccgc tgggagcaat ggctgttcac ccgcctgttc gagaagggcc
    48661 tgatctacaa gcgcctcggc acggtcaact gggacccggt cgacgagacc gtgctcgcca
    48721 acgagcaggt catcgacggt cgcggctggc gctcgggcgc actggtcgag aagcgcgaga
    48781 tccccatgta ctacatgaag atcaccgcct acgccgacga actgctgtcc gcgctcgacg
    48841 agctgccgaa ctggcccgag caggtcaagc tgatgcagaa gaactggatc ggccgctcgg
    48901 aaggcgtcga gatcagcttc ccgttcgatg tatcgagcat cggccacgaa ggcgtgctga
    48961 aggtgttcac cacccgcgcc gacaccctga tgggcgcgac ctacgtcgcg gtggccgccg
    49021 agcacccgct cgccacccag gccgccgccg ataaccctgc gctcgccgaa ttcatcgagg
    49081 aatgcaagcg cggcggcgtc gccgaggccg acctcgcgac gatggaaaag aagggcatgc
    49141 ccaccggcct caaggtgcgc cacccgctca gcgacgagcc gctcgaggtg tgggtcgcca
    49201 actacgtgct gatgggctac ggcgagggcg cggtgatggc ggtgccggcg cacgacgagc
    49261 gcgacttcgc cttcgccacc aggtacgcgc tgccgatccg catggtcgtc ggctcggacg
    49321 cctacgccga caccgtcgcc ccctggcagg acgcctacgc cgactacggc cgcctggtga
    49381 attccggcaa gtacgacggc ctcgacttcc agggcgcggt cgacgcgatc gcgggcgatc
    49441 tggccgccaa gggcctgggc gccaagcgtg tgcagtaccg cctgcgcgac tggggcatct
    49501 cgcgccagcg ctactggggc tgcccgatcc cgatgatcca ctgtgccgac tgcggcgacg
    49561 tgccggtgcc cgacgagcag ctgccggtgg tgttgcccga gaacgtcgag atcaccggcc
    49621 gcggctcgcc gctggccaag atgcccgagt tctacgagtg cagctgcccc aagtgcggca
    49681 agccggcgaa gcgcgagacc gacaccatgg acaccttcgt cgagtcgtcc tggtacttcc
    49741 tgcgctacgc ctgcgctggc agcacgaccg cgatggtgga cgagcgcgtc aactactggg
    49801 cgccggtcga ccagtacatc ggcggcatcg agcacgccat cctgcacctg ctgtactcgc
    49861 gcttcttcac ccgcgcgatg cgcgactgcg gcctggtcga tgtctccgag cccttcagcg
    49921 cgctgctcac ccagggcatg gtggtggccg agacctacta ccgcgagctc gacggcggca
    49981 agaagcagtg gatcaatccg gccgacgtgg tggtcgagcg tgacgagcgc ggccgcatcg
    50041 tcgccgccaa gctggcatcc gacggcctgc cggtggtcat cggcggcatc gagaagatgt
    50101 cgaagtcgaa gaacaacggc gtcgacccgc agtcgctggt ggatcagtac ggtgccgaca
    50161 ccgcgcgcct gttcatgatg ttcgccgcgc cgcccgacca gcagctcgag tggtccgact
    50221 cgggcgtcga gggcgcctcg cgcttcctgc gccgggtgtg gaactacggc cacgccttcg
    50281 ccaccgccac ccgcgccgcg ctacccgccg agcgcaagct cgccgccggc accctgcccg
    50341 ccgccgcggc cgacgtgcgc cgcgaggtgc atacccacct caagcaggcg agctacgact
    50401 tcggcaagca ccagttcaac accgtcgtgt cggcggcgat gaagatcctc aacgcgctcg
    50461 agaaggcgca caaggacctc gccggcgtcg agccggcggc ccacgccgag gtggccgagg
    50521 aaggcttctc gatcctgctg cgcctgctgt cgccgatcac cccgcacatc tgccacgcgc
    50581 tgtggcagga ctgcggcttc ggcagcgaca tcctcgccgc acaatggccc caggtcgcgg
    50641 aggacgcgct gaagcaggac gagatcgagc tgatggtgca ggtcaacggc aagttgcgcg
    50701 gcagcatcaa ggtcgccgcc gacgccgcca aggccgacat cgaggcgatc gccctggcct
    50761 cggaggcggc gcagaagttc atggagggca agccggcgaa gaaggtcgtc gtcgtacccg
    50821 gccgcctggt caatatcgtc gcgtgaggac gtccggcatg actgctcctg gacccgccgc
    50881 cacgggacgc cggcgcctgc tcggcagcgc gctcgcagcc acggtcgcgc tgttgtcggg
    50941 ttgcggcttc cacctgcgcg gcccgcaggc gctcgacttc gcgaccgtac acatcaacgt
    51001 cccggagcag agcgagttcg gcgcccagtt gcgccgcctc atcgccacca ccgggaccac
    51061 ccgggtggag gaggacgcgg ccagggccga ggcccgcctg cagatcctcg ccaacgaccg
    51121 cggccgcgag atcctcagcc tcaccggtgc gggcaaggtg cgcgagtacc agctcgtgca
    51181 ggcgctgcgc ttccagctcc tcgaccgcgc cggcaaggcg ctgatcccgc ccaccagcct
    51241 gtcggcgcgg cgcgaataca ccttcgacga cagccaggtg ctcggcaagg aacaggaaga
    51301 ggccctgctc taccgcgaca tgcagaacga ccttgtgcag cagctgatgc gcaggctcgg
    51361 cgccgcccgc cgcggcggct gaacccggcg cgccatcccc gcgtgaacct gcgccccgac
    51421 cagctcgccg cccagctcga gcgcccgctc gcgccgctct ggctgctgca cggcaacgaa
    51481 ccgctgctgg tgctcgaggc cgccgacgcg atccgcgccg cggcacgccg ccagggcttc
    51541 gaggagcgcg agaccctcgt cgtcggccac ggcttcaagt gggacgccct caccctcgcc
    51601 gcgggcaacc tgtcgctctt cggcggcgcc aagctgatcg acctgcgcat ccccaccggc
    51661 aagcccggcc gcgacggcgg cgacgcgctg cagcgctaca tcgcccacct gccctcgcag
    51721 accctgacct tggtcacgct gcccgaggtc gattgggcga cgcgcaagac cgcgtggttc
    51781 aaggcgctcg ccgacgcagc gacgacgctg gagctgaacg cccccgagcg cgagcgcctg
    51841 cccgattggg tcgcgcgccg gctcgccgtg cagaagcagt ccgccccgcc cgaggcgctc
    51901 gccttcatcg ccgatcacgt cgaaggcaac ctgctcgccg cccaccagga gatcctcaag
    51961 ctcgggctgc tgcacggcga gggcgcgctg acgctcgagc aggtgcagga cgcagtgctc
    52021 gacgtcgcgc gctacgacat cgacaagctg cgccaggcag tcgtcgaggg cgacccggcg
    52081 cgctgcgccc gcctgctcga gggcctcgag ggcgagggcg ccgccccgcc gctggtgctg
    52141 tgggcgctcg cccacgagac gcgcagcctc gccacgctgt gcgccgggcg cgacgcaggc
    52201 cagcccctgg ccaccctgtt caaggccgag cgcatcttcg acccgcgccg ccagcaggcc
    52261 atgacgcgcg cgctcggccg cctcggccag ggccacctgc gcgccgcgct gatgcacgcc
    52321 gcgcgcatcg accgcatgat caagggcctc gccagcggcg acctgtggga cgagttcctc
    52381 cagctcgccc tgcgcctggc gcgccgcggc tgaatcgcgg cgaaatcgcg cctcactccc
    52441 ggcaggcttc atccgcaccc ggttcgatgc tttaatgccg gcttgccctg cggcgtcccc
    52501 ggatgccgtg accgacgccg aagaagagcc cccatggaca tccagcacta catgcagacc
    52561 ctgggccgcc aggcccgcgc cgcctcgcgt gtgctcgccg ccgcctcgac cgcggccaag
    52621 aacgccgccc tgaccgcgat ggccgccgag atccgcgtgc gccgcgccga gctgctcgcc
    52681 gccaacgcgc gcgacgtcga ggaggcacgc gccgccggcc tggagccggc gctgatcgac
    52741 cgcctgacac tggacgagaa gggcgtcgag gccatggcgg ccggcctcga gcaggtcgcc
    52801 gccctgcccg acccggtcgg cgagatgagc gacatcaagc gccgcccctc cggcatcgcg
    52861 ctcggcaaga tgcgcgtgcc cctcggcgtg atcggcatca tctacgaggc ccgccccaac
    52921 gtcaccgccg acgccgcggc gctgtgcctc aagtcgggca acgccgcgat cctgcgcggc
    52981 ggcaaggaag ccatcaacgc caaccgcgcg atcgccgcct gcgtgcgcgc tggcctggtc
    53041 gcggccggcc tgcccgagca cgccgtgcag gtggtcgaga ccaccgaccg cgaagccgtc
    53101 ggcgcgctga tcaccatgcc cgagtacgtc gacgtgatcg tgccgcgtgg cggcaagggc
    53161 ctgatcgagc gcatctcgaa ggacgcgcgc gtaccggtga tcaagcacct cgacggcaac
    53221 tgccacgtct acatcgatga cgaggccgac cccgccaagg tcgtgcccat cgtcgagaac
    53281 gccaagaccc agcgctacgg cacctgcaac accgccgaat cgctgcttgt cgcgcgtgac
    53341 gtcgccgaca tctacctgcc cgagatcgcc cgcatgctcg ccggcaaggg cgtggagatg
    53401 cgctgctgcg ccgagtcgct cgccctgctg cgcgaggccg gcatcgccgg ggcgaagctg
    53461 gtggaggcga ccgaggccga ctggcacgag gagtacctcg cccccatcct cgcggtgaag
    53521 atcgtcgccg gcctcgacga ggcgatcgaa cacatcaacg gcttcagctc gggccacacc
    53581 gaagcgatcg tcaccgagaa ctattcccac gccatgcgct tcctgcgcga ggtagattcg
    53641 tcctcggtga tgatcaatgc ctcgacccgc ttcgccgacg gcttcgaata tggcctcggc
    53701 gcggagatcg gcatctccac cgacaagatc cacgcgcgcg gcccggtcgg cctggaaggc
    53761 ctgaccagcc agaaatggat cgtgttcggc aatggcgaag tacgccgctg acgcgacccg
    53821 cagaacgaat accaagaggg gacccatgag catccgcatc ctccgcagcc tgatcgccgc
    53881 cgccctgctc tcggccggcc tcgcccaggc cgccatcacc gtcggcaacg tcgacttcgc
    53941 cacgcggcag accgtgcagc agcgcgcgct cgagctcaac ggcgccggcc tgcgcacccg
    54001 cctgggcttc aaggtctatg cgatgggcct gtacctgcgc gcgccgctct ccgaggccgg
    54061 cgcgatcctc gccgacaagg gcgagaagcg catccgcatc gtgccgatcc gcgacctcga
    54121 ggcgaagcag ttcggcgacg ccctgcaggc cggcctcgag aagaaccacg acgccgccgc
    54181 gctcgccgca ctgaaacctg ccaccgacgc cctgctcgcg gcgctggccg cggtcggcga
    54241 ggtcaaggcc ggcaccgaga tcgtgctcga tcgcctcggc agcggcgcga cccgcctgct
    54301 ggtcgatgcg aagcagcacg gcgaggacat cgccgacgtc gccctctacc ccgcgctgct
    54361 gcgcatctgg ctgggcgagc gcccggccga cagcgacctg cgcgaggcgc tgctcaagaa
    54421 gccgcagtga gccgggcctc cgccatgccg gcgggcggcg cggacatgtc gacgttcgac
    54481 gcgatcatcg cgctgccctt cggccccttc ggcatccgtg cgcgcgacgg ccatgtgcgg
    54541 gagctcgtct tcctgccccc gggcacgccg ctgcacgacc cgcgcaacgc caccgccggc
    54601 gcagccgcgc atgcgctgcg cgcctggatc gaggcccccg acgagccctt cccggtgccg
    54661 ctcgcgccct gcggtacgcc cttccgccgc cgcgtgtggg cggccatcgc ggccatcccg
    54721 cgcggacgca cggcgaccta cggcgagctc gcgaccagcc tcggcagcgc accgcgtgcg
    54781 gtcggccagg cctgcggcgc caaccccttt cccctgatcg tgccctgcca ccgcgtgacc
    54841 tcggccgccg ggctgggcgg cttcgccaac gcccgcgagg gctggctgct cgaggtcaag
    54901 cgctggctgc tcgccttcga aggggcgctg tgagcggacg cgcaccggcg cgcgaggccg
    54961 gcctgcagcc cgcgcaccgc gccgagctcg accgcttcac cgacgcgctg tggctggagc
    55021 acgggctggc gacgaacacg ctggccggct accgcagcga cctcgcccgc ttcgccgcct
    55081 ggctggagac gcgcacgcag cgcctgcccg ccgtcagcgg cgcggatctc tccgcctatc
    55141 tcgccgagtt cagccgcgcc acgaaaccgg ccagccaacg ccgcctgatc gccgcgtggc
    55201 ggcgctacta ccgccttctg ctggccaatc gcgagatcgc cgaggacccc accctggcga
    55261 tcgacacccc gcaggcggcc gagcgctttc ccaagaccct gagcgaggcc caggtcgagg
    55321 ccctgctcgc cgcgcccggg ctcgacaccc cgcaaggcct gcgcgaccgc tgcatgctgg
    55381 aggtgctcta cgccgcaggc ctgcgcgtct ccgagctggt cggcctgaag gtcttcgcgg
    55441 tgggcgtcaa tgagggcgtg gtacgcgtga tgggcaaggg cagcaaggag cgcctggtgc
    55501 cgctcggcga gatcgccgcc gactggctgc agcgctatct ggccgaggcg cgcccgctcc
    55561 tgcttgcagg gcgcagctgc gacgaggtct tcgtgacccg cctgggggcg gcgatgtcgc
    55621 gccagatgtt ctggcgcctg atcaagcaat acgccctcgc cgccggcatc gcgcccgagc
    55681 gcatctcgcc ccacaccctg cgccacgcct tcgccaccca cctgctcaac cacggcgccg
    55741 acctgcgcgt ggtgcagctg ctgctcggcc acgccgacat ctccaccacg cagatctaca
    55801 cccacgtcgc ccgcgagcgc ctcaagcagc tgcacgcgcg ccaccatccg cgcgcctgaa
    55861 aaccgcgggt acgccagcac gggcgcgccc atacgccccg ggatggccga tggcactaca
    55921 atgacgggag tgcgccgccc ctttgcgatg gcgcctccga caggccgtcc gatcatgagc
    55981 agaaacgaag cccacgcccc cgagaccccc gccacccgct tcctgcgcca gcacggcgtg
    56041 gccttctcca gccatctcta cgagtacgag gagcacggcg gcaccacggt gtcctcgcgc
    56101 gagctcaacg tgcccgagca cgcggtgatc aagaccctga tcatggagga cgagaacgcg
    56161 cagccgctgg tggtgctgat gcacggcgac cataaggtgt cgaccaagga gctcgcgcgc
    56221 cagatcccgt gcaagcacgt cgagacctgc aagcccgaga ccgccaaccg ccacagcggc
    56281 tacctggtgg gcggcacctc gcccttcggc acgcgcaaga agatgccggt gtacatggag
    56341 cgcaccgttc tcgacctacc gttgatctac atcaacggcg ggcggcgcgg cttcctggtc
    56401 gggatccacc cgcacgacct gctgcgcgtg ctgcagccca ggctggtgca ggtggcgaac
    56461 tgaggcgggc gcccgcgggc gctcaggcgg ccggcggcac gaccacgccc gccttgctgc
    56521 gctggatgta gacgccgacg cggcgcacgt ccttcatcac cccgatcttg cccaccttga
    56581 gcttgaccca gggcgcgccg aactcctcga acagcagctt gacgacgaac tcgcccaggc
    56641 tctcgatgag gttgaagtgg cgctcgccga gctcgcggcg gatacgctcg gtcacgacgg
    56701 catagtcgat ggtgtcggcg atgtcgtcgt gctcggcagc ggcgtcgggc acgccgaagg
    56761 tgaggttcag ctcgaccgtc tgcgggccgg tcttctcgcg cgcgtagatg ccgacccagg
    56821 ccttgacgcg cagttcctcg atgaagatga aatccatgct gcttcccgtt tagaatcgcc
    56881 cggattctaa cgcgcccccg cccccgcgcc ggtaaaagct gtcgtccgcg cgcggccggc
    56941 gtgcggacga ggtaaggccc gcacctgcag tcccgggctt gcgtaccccg tcttccgtcc
    57001 ctttagagct gcccgccgac gggcagcgga gccaagatgt ccaccctgct tctgatcgtc
    57061 gccgcctacc tgctcggctc cattcccttc gcgatcgtca ccagccgcct gttcggcctg
    57121 gaggatccgc gcaagtacgg ctcgggcaac ccgggcgcca ccaacgtgct gcgcagtggc
    57181 aacaaggccg cggccgtgct caccctgctc ggcgacgcgc tcaagggctg gctggcggtg
    57241 tgggcggcgc tgcggctcgg cttcgagccg gacatcgccg cgctcgccgg cctcgccgcc
    57301 ttcctcggcc acgtgttctc gctcttcctg cgcttcaacg gcggcaaggg cgtggccacc
    57361 gcgctcggcg tgctcgccgg ggtcgatgcg cgcatcgcga tcttctgcgc ggtgatctgg
    57421 ctgatggtgg cctacaccac gcgctactcc tcggccgcag cgctgtcggc cgcgctcgcc
    57481 gcgccgctcg ccggtttcct cttcctcggc gccaagccgg ccgtggcggt gctcgcggtg
    57541 atgacggcgg tgctgttctg gcgccacaag gagaacatcg cccgcctgcg cgccggcacc
    57601 gagggcaaga tcggcggcaa gaagaaggac gggccgacgg cgtaagacgc ccgggcaacc
    57661 tgttcgcagc tgccgcagcg cctacatgaa ccatcgcaac tccggtttta tgtaggagcg
    57721 ccggcaggcg cgaacacggc gacggaaccg cggcagcgcg agtgccggac acccggttcg
    57781 cagctgccgc agctcctgcg cgagacgaag ccgcgacggt gcatgtagga gcgccggcag
    57841 gcgcgaacac ggccctggag ccgcggcggt gcgagcgccg ggcgccgtat tcgcggcttg
    57901 cgccgctcct acacgacgcc ggacacctgc accggcgggc gcagctcgac catgggccag
    57961 cgcgggcgga tgcgtacggc ggcgacctcc ggcccggtct cgccggccgc cagacgcagc
    58021 gcgccggcga aggcgatcat tgcgccgttg tcggtgcaca gcgccggctc cgggtaatgc
    58081 acccgcccgc cgcggcgcgc gagcgcggca tcgagcgtgg cgcgcaggca gcggttggcg
    58141 cccaccccgc cggccaccac cagggtcttg agccccacct tcttcagcgc cgcaagcgcc
    58201 ttcgcgcaca gcacctcgac caccgcctgc tggaattccg cggcgagatc ggccatgcgc
    58261 accggatccc agtccggtgc cgagaccacg ttgagcaccg cggtcttgag gccactgaag
    58321 ctgaagtcga ggtcgcccga gtgcagcatc ggccgcggca ggcggaagcg cccaggcacg
    58381 ccggactcgg cgagctgcgc cagctgcggt ccgcccggat agcccaggcc gagcagcttg
    58441 gcggtcttgt cgaaggcctc gccggcggcg tcgtccaccg actcgccgag cagcgcgtag
    58501 tcgcccaccc cgcgcacccg catgagctgg gtgtggccgc ccgagacgag cagcgccacg
    58561 aaggggaagg cgggcggatc ggccgacagc agcggcgaca gcaggtggcc ctcgaggtga
    58621 tgcaccggca gcgccgggat cccgcgcgcc atcgcgaagg actccgccac gctcgccccc
    58681 accagcagcg cgccggcgag cccgggcccg ctggtgtagg ccacggcgtc gacgtccgcg
    58741 gcggccagcc cggcctcggc cagggtctgg cgcagcagca gcggcaggcg gcggatgtgg
    58801 tcgcgcgagg cgagctcggg cactaccccg ccataggccg cgtgcaggtc gatctgcgag
    58861 tgcaggcagt gcgcgcgcag gccggcctcg gtgtcgtaga tcgccacgcc ggtctcgtcg
    58921 caggaggttt cgatgccgag cactttcatc gggatgcatc cgtttgattc ggtgtcgcat
    58981 tttaacccgg cgccgtagcg cgtgcgaccg gcggccttgc catcgacggg cgtctggttt
    59041 atattcgcgg tctttctgcc caccagacac ccaaggaagt ccgcaatgcc cggtatccgc
    59101 gtcaaggaaa acgagccgtt tgaagttgcg atccgccgct tcaagcgcac catcgagaag
    59161 accggtgtgc tgaccgaact gcgctcgcgc gagttctacg aaaagcccac cgccgagcgc
    59221 aagcgcaagc tggccgccgc cgtcaagcgc aaccacaagc gcctgcgcag ccagacgctg
    59281 ccgccgaagc tctactgatt cggctcgcgc cccgcactcg cgggacgccc atgcccgccc
    59341 tcgcgggcga tcacacgccg gcccggggtc gctcgatccc cgcccggcgt gatgcttttt
    59401 cacgaacacc cgtcgtccgc gcatgcggac gggacgggcg tttgcttttg cgcgcgcgat
    59461 gatcccccag tccttcgtcc aggaactgct ttcccgcgtc gacatcgtcg acgtcatcga
    59521 acgctacgtc ccgctcaaga agagcggcgc caactacttc gcctgctgcc ccttccacgg
    59581 cgagaaatcc gcatcgttct cggtcagccc gtccaagcag ttctaccact gcttcggttg
    59641 cggcgtgcac ggcagcgcgg tgggcttcct gatggaatac agcggcctgg gcttcgtgga
    59701 cgcggtcaag gagctcgccg cgcaggtcgg actgcaggtg cccgacgacg gccgcagcgc
    59761 gacgccggcg catgacgacg ccagcgagcg tctttacgag gcgatggcga tggcggcgcg
    59821 cttctatcgc gaccagctca agccctcgcg cgcggccatc gactacctca agcgccgcgg
    59881 cctctccggc gagatcgccg cgcgcttcgg cctcggctac gcaccggacg agtggcaggc
    59941 gctggagagg atcttcccgg actaccaggc gaagaccctc gccgatgccg gcctggtcat
    60001 cgacaacgag caggggcggc gctacgaccg cttccgcaac cgcatcatct tcccgatcca
    60061 cgaccgccgc gggcgcatca tcgccttcgg cgggcgcgtg ctcggcaagg gcgagcccaa
    60121 gtacctgaac tcgcccgaga ccccgctgtt cgagaagggg cgcgagctct acggcctctt
    60181 cctggcgcag aaggcgatcc gcgacgccgg cttcgcggtc gtggtcgagg gctacatgga
    60241 cgtggtcgcg ctcgcccagt tcggcatcga gaacgcggtc gcgacgctcg gcaccgcaac
    60301 cacgccgcag catatccaca cgctgctgcg ccagaccgac cgcatcgtgt tctgcttcga
    60361 cggcgacgcc gccggccgcc gcgccgcctg gcgcgcgctc gagaacgcgc tcgaatccct
    60421 gcgcgacgac gccaccctgg ccttcctgtt cctgcccgcc gagcacgacc cggactcctt
    60481 cgtgcgcgcc gagggcgccg aggccttccg caaggccgcg ctcgccgcca ccccgctggg
    60541 cagcttcctg attcaggagc tctgcggccg ccacccgctc gacagcgccg agggccgcgc
    60601 ggccttcgtg cacgagtcgg cgccactggt cacccgcatc gccgcgccgc tgttgaagct
    60661 gcaggtggtg aaggcggtag ccgagaccgc gggcatgacc cagggcgagg tcgaatacgc
    60721 cttcgagcag ctcgccgcca gcgccccgcg ccggcgcggc accgaggcac ccaccccggc
    60781 ccgcgcaccc gccacgagcc cccctagcgc cgaggcggat gcgcccttcc tcgacgaggc
    60841 gcgcccaccc gcccgcagca cgccgccacg cggccaggcg ccacgtccgc gtccgggcgg
    60901 tcggcgcaag ctgccctcca ccgccggcac cctgctacgc ctggtgatgc agcaccccac
    60961 ctgggccgcg cgcatgccgg tcggcctggt gcccgacgac agcccggaag gcctcgcgct
    61021 gatcgcgatc atcgacctct tcagcctcgg cgagccgatc ccggctggcg gcctcggtgc
    61081 gctgatcgag cgcttccgcg aaacccccca cgccgacacc ctctcgcgcg tcgccgcgga
    61141 actcgtcgag gcggaattcg acgaagcggt ggtcgagacc ctgttcgagg acgccctgcg
    61201 caagctgcag gtcgacggca tcggcaagga gatcgccgcc ctgctacaac gggatcgtga
    61261 gcaaggcctg gacgccgccg gccgccatcg cctgggagag ctgctgctcg agaagcggaa
    61321 cctcgccggc ggcggcaaag tctcagattt atagtacaat tttcggtttc ccatttactt
    61381 acaccctcac ttgaggagtg ctatggcacg cgaaaaagcc aaggacccgc gcaaggacgc
    61441 ccccgcaaag ggtcgccctg ccaaggccaa ggacaagtca gccccggtga tcgaaagccc
    61501 cgccgccacc ccgctcgacg cggaggtgcg ccgcacccgg ctgaagacgc tgatcacgct
    61561 cggcaaggaa cgcggctatc tcacctacgc cgagatcagc gaccacctcc ccgacgacgt
    61621 ggccgatgcc gaacagatcg aaggcatcat cgccaccttc aacaacatgg gcatccaggt
    61681 ctacgacgag gcgccggccg ccgaagatct gctcatgtcg gacagcgtcg ccaccaacgt
    61741 ggatgaggac gtcgccgaag aagaggccga acaggcgctg tcctcggtcg attccgagtt
    61801 cggccgcacc accgacccgg tgcgcatgta catgcgcgag atgggcacgg tcgagctgct
    61861 cacccgcgag ggcgagatcg agatcgccaa gcgcatcgag gacggcctca agcacatggt
    61921 gcaggccatc tccgcctgcc cgacgacgat cgccgagatc ctcgccatcg tcgaccgcat
    61981 cgccgccgac gaggccaaga tcgacgagct cgtcgacggt ctgatcgacc ccaacgccgg
    62041 cagcgccgac gaggccgccg cggaagagga agccaccgag gacgacggcg aggccgaaga
    62101 ggacgagggt gccggggacg aggacgaggg cgacgaagag gaagacagcg ccgagagcgc
    62161 ggagcgcgcc aacgccgcct cgctgctgca gctcaagaac gacgcgctcg cccgcttcga
    62221 cgtcatccgc gggctgtacg cgaagaagat gcaggcgctc gagaagcgcg gctctcagga
    62281 cctctcctac ctcgcgctgc agcagcagat ctccgacgag ctgctcaaca tccgcttcac
    62341 cgccaaggcc atcgagaagc tgtgcgactc ggtgcgtcac atggtcgagc aggtacgcag
    62401 ccacgaacgc cagatcctgc aactgtgcgt ggatcgcgcc ggcatgccgc gccagcactt
    62461 catcaaggtc ttccccggcc aggaagtgaa cctcgactgg ctcaaggacg agatcgccgc
    62521 cggcaagaac tacgccgacg gcctgatgcg catccacccc gcggtgctcg aggagcagca
    62581 aaagctcatc gacctgcagg accgcatcgg catcccgctc aaggagctca aggacatcaa
    62641 ccgccagatg tccaccggcg aagccaagat gcgccgcgcc aagcgcgaga tgaccgaggc
    62701 caacctgcgc ctggtgatct cgatcgccaa gaagtacacc aaccgcggcc tgcagttcct
    62761 cgacctcatc caggaaggca acatcggcct gatga
//
LOCUS       DAOTIN010000006        61806 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_452_length_61806_cov_9.719017, whole genome shotgun sequence.
ACCESSION   DAOTIN010000006 DAOTIN010000000
VERSION     DAOTIN010000006.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 61806)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 61806)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61806
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_452_length_61806_cov_9.719017"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..480
                     /locus_tag="P5537_01750"
     CDS             <1..480
                     /locus_tag="P5537_01750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002928771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HRV76796.1"
                     /translation="VAAMNPCPCGHLGDPRRACRCTPDQVARYRGRLSGPLLDRIDLT
                     VEVPAIAPEALFQSPPGEPSAAVRARVVAARALQAARQGCPNARLPAGEVERQCRPDP
                     GGETLLRQAMQRLGLSARAYHRVLRVARTLADLAGAERPGAAQVAEAIQYRRSLDTR"
     gene            547..1779
                     /locus_tag="P5537_01755"
     CDS             547..1779
                     /locus_tag="P5537_01755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug effflux MFS transporter"
                     /protein_id="HRV76797.1"
                     /translation="MTRPLTHARLASLLAALSSIGPFAIDAYLPAFPAIGAALGASQL
                     EVQQTLTIYMAALAAMVLWHGALADRFGRRRVLIALTVVFALASLVCALAPSIEWLWV
                     GRALQGLSGGAGIVVGRAVVRDLHEGPQAQRLMSRVMLIFALAPALAPLVGAGLLALA
                     GWRAIFLFLTLFGFVLAWVTWRFLPETLAEEDRQPLHPLALLRAYLAIFRHPGFLLLA
                     LGVALNFNGFFLYVLSAPVFILEHLGLGSGGFVWLFGPAVGGMMIGSMLSERMAGRWS
                     PVRTVGTGFVLMFAAVVANAAVSGLFAPGVPRSVLPIGLFSCGMAVAMPSMSLLGLEL
                     FPERRGMASSCQSFLQIGFNAASSALVAPALWSSPLGLASGMGMFAALGLCTWLAWRR
                     LAGRGPATARLGEMAPRP"
     gene            1928..2767
                     /locus_tag="P5537_01760"
     CDS             1928..2767
                     /locus_tag="P5537_01760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV76798.1"
                     /translation="MLEVDGLVKAFGGFRAVDGCTLRVGKGEILGLIGPNGAGKTTLF
                     NLVAGALQPTLGTIRFLGEDITALPTDARFHKGLVRTFQIPHEFHNLSARENLMMVPP
                     RQPGENLFANWFAAGKVRAAEEAVRKKADDTLAFLELTHVADERAGNLSGGQKKLLEL
                     GRTMMTEAKLVLLDEPAAGVNRTLLRKLEEKILILNRERGYTFILIEHDMEMIEKLCD
                     PVVCMAEGKVLIQGDFQTVRSDSRVLEAYLGETPTAVEREAAEHDPKVEELREQELHR
                     EDL"
     gene            2767..3471
                     /locus_tag="P5537_01765"
     CDS             2767..3471
                     /locus_tag="P5537_01765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV76799.1"
                     /translation="MALLDMKDVRGGYGDADILHGVSMTVGEREVVVIVGPNGAGKST
                     AMKSVFGLLTIRGGSIVFDGEDITGWAPDRIVQRGICYVPQVDNVFREMTVHENFEMG
                     AFLRRGDLSAAYDRIYGLFPDLKAKRRNLAGDLSGGQRQMVAMGRALMLDPKLLLLDE
                     PTAGLSPKYMEQIFQITRDVRDAGVSILLVEQHAKQALAFCDRGYVLATGANRHEGSG
                     QALLADREVAEMFLGG"
     gene            3487..4356
                     /locus_tag="P5537_01770"
     CDS             3487..4356
                     /locus_tag="P5537_01770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002928778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HRV76800.1"
                     /translation="MSFLEFLNFHLVPGVVLGSIYAVGAIGITLVFGILRFAHFAHGD
                     MATLGAFVALALVTAGLTPWAALPIAMAAVAVVAIVVDKLFYDYLKARPKIMTVMASL
                     GVALMLRAVVQVVFGVDPRTYATGIVRPDEYFGILLRDRELYTLAAVVLLVVGLSLFL
                     RHSRWGKAMRAMSDNPDLARLSGVDNRKVTMLTWAIVGALCAASGFMLGINNELHSMM
                     GWQVLLPMFAAAILGGVGRVEGAVLGGLIVGIAEEMSIFILPAQYKAATAFVLLLLIL
                     LVRPRGLLNGKVL"
     gene            4356..5300
                     /locus_tag="P5537_01775"
     CDS             4356..5300
                     /locus_tag="P5537_01775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HRV76801.1"
                     /translation="MDLLGLANYAVFMAILIGIYALLALGLNIQWGFTGLFNAGIAGF
                     FAVGAYTSAILTSLPASGRLGGYELPLLLGWAASMVAAAAIAWPIGKICLRFRSDYLA
                     IATIGIAEIIRLVIRTEGWLTGGVRGVTGIPRPFGELDYMPSQIAYLAIVATLVLVAY
                     LLVERQVKAPWGRMMRAIRDNELAAAAMGKQVEARRLQAFVFGSALMGLAGALFVHFN
                     RSVTPEAIDPMIATFLIWIMLILGGSGNNRGAILGAAVIWIIWSVSELLTDRLPTEIA
                     VQAKYARVFIIGLTLQLVLRFRPEGILPERQPGSPPHR"
     gene            5395..6600
                     /locus_tag="P5537_01780"
     CDS             5395..6600
                     /locus_tag="P5537_01780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002928780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HRV76802.1"
                     /translation="MNKKAIAGLVGAMLGAAVVAAPAHAQDVKLGLMAAISGPIAALA
                     PPMAAASKLAVAHVNEQGGILKGGKLEAVLGDSACNPQNATDVATKAVNIDRVLAVVG
                     PACSGAVLASANSVTIPAGVLMITPSGTSPEITKLKDKDLVYRTLPSDDYQGRALART
                     LKARGISKVAVAYLNNDYGKGLAESFKAEFEANGGTLAGYSGHEEGKASYRSELATLA
                     RGGADTLVIFDYGDGTGLSILRQALENNFFKTFVGADGMKSEGLVKAIGAANLGGFFV
                     SAPVGEASASLDNFNKAYKAAGENIDAVFATTSYDAAFLAALAIEKAGGDKAKLAESL
                     RAVASAPGEPILAGEWAKAKKLIAEGKDIDYKGAGGDHEFDAAGDVPGNYAFFKVSGT
                     GYESIADMK"
     gene            6885..7376
                     /gene="bamE"
                     /locus_tag="P5537_01785"
     CDS             6885..7376
                     /gene="bamE"
                     /locus_tag="P5537_01785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamE"
                     /protein_id="HRV76803.1"
                     /translation="MKRFLAWICGLLSAIGITACDYINVKELQPGVSTSAEVRERFGP
                     PHMEWRNEDGSLTWEFSRQPQGVECFMITIGADQILRRIDQVLNEETFAKVQNGMNGD
                     QVRRLLGKPASSQFFQLKQETVWEWRISHGPNGTSDPVFFTVSFNNDGRVTGTGRYTQ
                     YKH"
     gene            7468..8013
                     /locus_tag="P5537_01790"
     CDS             7468..8013
                     /locus_tag="P5537_01790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76804.1"
                     /translation="MLAGCASFAPPRPYTTEAEALSARGEPTRRWSNDDGTTTLEYST
                     QPNGRTCLMVQVDQGGIVLRQWDALAAENLARVERGMDKEQVSRLLGTHRSEQRFRNS
                     GEEVWDWNIRNDGPGIATLFNVHFIDGKVVRTSQTYVYPRDGAVFGGWSGYYGHPWGW
                     GIGFGYPGPFFPRPFGHPFFW"
     regulatory      8060..8134
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01057"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="S-adenosyl-L-homocysteine riboswitch; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosyl-L-homocysteine"
                     /db_xref="RFAM:RF01057"
     gene            8211..11960
                     /gene="metH"
                     /locus_tag="P5537_01795"
     CDS             8211..11960
                     /gene="metH"
                     /locus_tag="P5537_01795"
                     /EC_number="2.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008705 - methionine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0031419 - cobalamin binding [Evidence
                     IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HRV76805.1"
                     /translation="MQADRTTELRQLLAERILILDGAMGTMIQQEKLGEADYRGERFL
                     DHPKDLKGNNDLLVLTRPQVIAGIHRAYLEAGADIIETNTFNATRVSQAEYGLEALAY
                     ELNVEGARLVRRLCDEYTARNPARPRYCAGVLGPTSRTLSISPDVNDPGYRNVSFDAL
                     VDDYYDSAKGLLEGGADLLLIETIFDTLNAKAAVFAIERLFEDLGRRWPVMISGTITD
                     ASGRTLSGQTAEAFWNSLSHAQPISFGLNCALGADQLRQYVEELSSVCDTHVSAHPNA
                     GLPNPLSPTGYDETPEHLAGEIREWAQSGLVNIVGGCCGTTPAHIAAIAQAVAGLAPR
                     AVPVLEKKLRLSGLEPFNVGGDSLFVNVGERTNVTGSKAFARMILEGRFDDALAVARQ
                     QVENGAQVIDINMDEAMLDSVAAMERFCKLIASEPDISRVPIMLDSSKWSVIETGLKC
                     IQGKGVVNSISMKEGEAEFLRQARLARRYGAAVIVMAFDEQGQADTFRRKTEICARAY
                     TLLTKPVAEGGAGFPAEDIIFDPNIFAIATGIEEHDNYAVDFINAVAWIKENLPYAKT
                     SGGVSNVSFSFRGNDPVREAIHTVFLYHAIKAGLSMGIVNAGQLGVYDELVPELRDKV
                     EDVVMNRRPGAGEALVEFAQTVKGQAKESAQDLAWREWPVEERLSHALVKGITEFVVA
                     DTEEVRAKLEAEGRPPLAVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAH
                     LIPYIEAEKLRTGASSKGRIVIATVKGDVHDIGKNIVGVVLGCNGYEVIDLGVMVPAA
                     KILEAAKEHGAQAIGLSGLITPSLEEMSHVAAEMKRQGFSVPLLIGGATTSRNHTAIK
                     IAPHYDQPVVYVPDASRAVGVVTALLSEGQSEAFKAEVAADYEKIRALHANKKGVQLV
                     SLEAARANGFRTDWTAERVAACSTAHQAGYAPYQPPRPNMLGVQAIDVELGELVNYID
                     WGPFFQTWDLAGRFPAILDDEVVGETARNVFADGKAMLDRIVAEEWLQAKAVFGLFPA
                     NAVDDDIELYTGEDRKHLAMVWHGLRQQHERPTGKPHWCLADFVAPRDSGVPDWVGAF
                     AVTAGLGIEAKLAEFEAAHDDYHAIMLKSLADRLAEACAEWLHERVRRECWGYAADET
                     LGNEALIREEYRGIRPAPGYPACPDHTVKGPLFELLGARERIGMELTESYAMMPAAAV
                     SGFYFAHPESHYFAIPKIGRDQLEDWARRTGMEVDEAARWLAPLL"
     assembly_gap    12205..12304
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(12444..13292)
                     /gene="fghA"
                     /locus_tag="P5537_01800"
     CDS             complement(12444..13292)
                     /gene="fghA"
                     /locus_tag="P5537_01800"
                     /EC_number="3.1.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018738 - S-formylglutathione hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0046292 - formaldehyde metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-formylglutathione hydrolase"
                     /protein_id="HRV76806.1"
                     /translation="MTTAPEQLAANRSFGGWHRRFRHRSAALGCDMVFAIYLPPQAEA
                     GPVPVLYWLSGLTCTDENFMQKAGAQRLAAELGIAIVAPDTSPRGTGVPGDPDGAWDF
                     GLGAGFYVNATEEPWRRHYRMYDYVVEELPALVEAHFPVSDARAISGHSMGGHGALVC
                     ALKNPGRYRAVSAFAPIANPSACPWGEKAFARYLGADRARWLEWDACALIAGTRERLP
                     LLVDQGEADGFLAEQLRPEALRAACAAAGHPLNLRLQPGYDHSYYFIASFIDDHLRHH
                     AAALRG"
     gene            complement(13307..14416)
                     /locus_tag="P5537_01805"
     CDS             complement(13307..14416)
                     /locus_tag="P5537_01805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003984083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004024 - alcohol dehydrogenase activity,
                     zinc-dependent [Evidence IEA];
                     GO_function: GO:0051903 - S-(hydroxymethyl)glutathione
                     dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0006113 - fermentation [Evidence IEA];
                     GO_process: GO:0009404 - toxin metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-(hydroxymethyl)glutathione dehydrogenase/class
                     III alcohol dehydrogenase"
                     /protein_id="HRV76807.1"
                     /translation="MRSRAAVAWAAKQPLEVTEVDVAPPRAGEVLVRIIATGVCHTDA
                     YTLSGADPEGIFPAILGHEGGGIVEAIGEGVSSVAVGDHVIPLYTPECGKCKFCLSGK
                     TNLCQAIRATQGKGLMPDGSSRFSKDGKPIFHYMGTSTFSEYTVLPEISVAKIRKDAP
                     LDKVCLLGCGVTTGIGAVRNTAKVEAGASVAVFGLGGIGLSAIIGAVMNKAGRIVAVD
                     INPEKFEIARQLGATDCINPLDYDRPIQEVIVDLTDGGVDYSFECIGNVKVMRSALEC
                     CHKGWGESVIIGVAGAGEEISTRPFQLVTGRVWRGSAFGGVRGRSELPGYVDMAQRGE
                     IPLDTFITHRMGLEDINKAFDLMHEGKSIRSVILY"
     gene            14539..14916
                     /gene="trxA"
                     /locus_tag="P5537_01810"
     CDS             14539..14916
                     /gene="trxA"
                     /locus_tag="P5537_01810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HRV76808.1"
                     /translation="MATLELTAENFNETVEQNPIVFLDFWAAWCGPCRNFAPTYEAAA
                     EANPDIVFGKVDTEAQQDLAAAFQIRSIPTIAVIREGVMVFRESGALPASALNQVIEG
                     VRGLDMDQVRAEIAQQQAGAQQG"
     gene            complement(14947..15864)
                     /locus_tag="P5537_01815"
     CDS             complement(14947..15864)
                     /locus_tag="P5537_01815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001216 - DNA-binding transcription
                     activator activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HRV76809.1"
                     /translation="MVNSDLNYKHLRYFWTVARVGTIAEAGRVLGLAPHSISAQLATF
                     EGALGVTLFRRSGRRLALTEAGERILGQAEEIFALGDQIVETLRDDSLRRSLPFRIGI
                     PDSMPKSMVHRLIEPALRLERPGRLVCRESPLSELLAELAVHRLDLVIADRPIPPEVS
                     VRGHESLLGESTLSVFAAPALAARLQGGFPRLLDGAPFLLPGEDVAHRGALLQWFERM
                     RIRPAIVAEFDDSALMKAFGQAGDGVFAAPTTIADYVCRQYGVRLLGEVPDARARVYA
                     ITTERRLLHPAMQAIRNAAARALTPAPPG"
     gene            16019..16411
                     /locus_tag="P5537_01820"
     CDS             16019..16411
                     /locus_tag="P5537_01820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerB family tellurite resistance protein"
                     /protein_id="HRV76810.1"
                     /translation="MRHYETNSTPAAARLLALTVLADGGLDRNEVDTMMHTDLARRLG
                     IGSVEFERILREYCDDLMLSAHYLDGVRLKVADEVLDLLLEDIADPRLQQALLRTMQD
                     IVSADGVETSAEVEVLARALEKWGSRPH"
     gene            16492..16965
                     /locus_tag="P5537_01825"
     CDS             16492..16965
                     /locus_tag="P5537_01825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-starvation-inducible PsiE family
                     protein"
                     /protein_id="HRV76811.1"
                     /translation="MEAMRPGTGKAHDNHLGDRVDDPLIDRLHWIIRQAIRVLAVLMV
                     AVILWTVADVVLVLYEKLSDPPFLLLDLNDIFVVFAAFLAVLIAIEIFVNITLYLRDD
                     VIHVKLVIATALMAIARKVIVLDLTTLEPMYLFAIGVIVLALGVTYWLVSARPGD"
     gene            complement(16987..17931)
                     /locus_tag="P5537_01830"
     CDS             complement(16987..17931)
                     /locus_tag="P5537_01830"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002928812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0002189 - ribose phosphate
                     diphosphokinase complex [Evidence IEA];
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HRV76812.1"
                     /translation="MIKHGLQIFACNASRELACDISNRLGMRPGRIDIARFSNDNLRV
                     QIQENVRERDVFVVQSFTEPVSEHIMELMITLDALRSASAQRITAVIPYYSYARSDKK
                     DAPRISITGRLIADLLQTAGANRVLTMDLHADQVHGFFSVPVDHLTAVSLIADHFRNR
                     HDLSNMVAVATDAGGAKRTGRFSEKLGIPMAIIDKRRVSDTAVKQGAVVGEVAGRDVV
                     IFEDEIATAGTLVSSVDTLKAAGARSIHAAATHGVLCGPAIERLRAAAIDSVVVTNTV
                     ALPEDKRLDKLTVLNVAPLFAAAIERIHSGQSVGALFE"
     gene            18210..19811
                     /locus_tag="P5537_01835"
     CDS             18210..19811
                     /locus_tag="P5537_01835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HRV76813.1"
                     /translation="MNALASALGRLRGDFFGGLTAGIVALPLALAFGVASGAGAAAGL
                     YGAIVLGFVAALLGGTRMQISGPTGPMTVVFASALVAVGGDLAVAMAAVLVGGLVQIG
                     LGVLRAGGLVRFIPYPVVSGFMSGIGVIIVLLQSAPLLGVAPAPSPQGAVLALPGVLA
                     NVNGEALLLGGLTLLIVFRTPMAVSRIVPAPLVALVGMSALSVAAGLQVPVIGDIPAG
                     LPELVLPSFTLETWTTVALLGITLGVLGSIDSLLTSLVADSITRTRHHSNRELIGQGI
                     GNLLCAFVGGLPGAGATMRTVINIKSGGRGRGSGVVHALFLLALLLGLGPLAERIPLA
                     VLAGILIKVGVDILDYRMLRLVRTAPRADVGVMAAVFALTVLVDLIVAVGAGVILSMA
                     LIIHRLARQSRLRVRPLPHVEEGGGEPAGHELPGLDSGVRVIEIEGAFFFGSASQLLD
                     RVDQVIGTRVVVFDCSRVPFMDLSAQFALEEMIEGLHAQSIAARVVVPPEIHAQLLRL
                     GAPQLPAAILRDDLDRALAEAREMA"
     gene            complement(19903..20769)
                     /locus_tag="P5537_01840"
     CDS             complement(19903..20769)
                     /locus_tag="P5537_01840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="THxN family PEP-CTERM protein"
                     /protein_id="HRV76814.1"
                     /translation="MKATTRKSLKTTMCAMATALAALGAPAAHATLINGIVDTWTVKV
                     DAKFLTSTVLWDDTNGSGGTTTVSDTQLVWGQPATSSGQSSLTLTDFNTTKQVATNGA
                     SVSNLTLTHANNPVTGRTLDQVSLSSTLTLTPFSPSATGLSPVTLSFLINFDETTNNA
                     NPCANGGANGTGVNSNGCGDIFVIDKDSLNFPFFYDLDGVGGPLQNQKYFISFFEQTS
                     GLTPLSTAACTAAGASTPCLGFVTPEQATTPAIFAALITTEPVTIPEPGTLAILGLGL
                     AGLGLMRGRRKA"
     gene            complement(20946..22166)
                     /locus_tag="P5537_01845"
     CDS             complement(20946..22166)
                     /locus_tag="P5537_01845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011237658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1343 domain-containing protein"
                     /protein_id="HRV76815.1"
                     /translation="MAHPVRFGLDRLLQEPELRRPLAGRRVALLAHPASVTRDLTHSL
                     DALAALPDLELSAAFGPQHGLRGDKQDNMVESPDYTDPLLGIPVFSLYGEVRRPTAAM
                     MDTFDVLLVDLQDLGCRIYTFITTLRYVLEEAARHGKAVWVLDRPNPAGRPVEGTLLR
                     PGWESFVGAGPLPMRHGMTMGELAHWFVATLELDVELRVIEMQGWRPEAAPGYGWPLG
                     ERSWINPSPNAPNLWMARAYAGTVMLEGTTLSEGRGTTRPLELFGAPDLDARALIAEM
                     RGLAPEWLQGCVLRECWFEPTFHKHTGRLCNGVQIHVEDPAHYQHAAFRPWRVQALAF
                     KAIRRLWPDYPLWRDFPYEYEHDRLAIDLINGSPLLREWVDDTAAAPAELDALAMTDE
                     RRWRHERERFMLYE"
     gene            complement(22171..22791)
                     /locus_tag="P5537_01850"
     CDS             complement(22171..22791)
                     /locus_tag="P5537_01850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DOMON-like domain-containing protein"
                     /protein_id="HRV76816.1"
                     /translation="MTQPLTERPRVPIITVGLRPHPTSPDAEAPGQGLVGRLLATMFA
                     LPEGGAVFEFRLEDSRVAQLAVPTPATPGPADELWKHTCFEVFLGAPGEPGYREYNFS
                     PSGQWAVYGFRAWRERIEDYVPAAAPEILFSQADDGLVLEARVPAELLPAVPAGSDLQ
                     VSLAAVVERKDGTLEYWALRHAAAQPDFHARDTFVLTLATATHKAD"
     gene            23039..24214
                     /locus_tag="P5537_01855"
     CDS             23039..24214
                     /locus_tag="P5537_01855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HRV76817.1"
                     /translation="MRAPPLLVIVLAQLFGTSLWFSANAAGEDLLRTWSLQPADIGRL
                     TIAVQLGFIAGTLGFSLSGLADRFAASRIFAVCAVVGALANAGFALLAQGLGEGLVWR
                     FAVGLALAGVYPLGMKLVVSWVPQQAGAALAWLVGMLTLGTALPHGVRFLDAGWGWQA
                     TLLVSSLLALLAAAMIFKLGDGPHLARRAGAPRLRLGEGLYALRSPAFRASAFGYFGH
                     QWELYAFWTLVPLLVSAARGAEAGLPSGPAFAVIGIGAVGCVLGGWLSRRIGSARVAA
                     LALAVSALCCALYPFATAWPPLALAGLMLLWGASVVADSPHFSALSARACPPESVGSA
                     LAFQNAIGFAITMVSIELVTRLWPSIGDRVAWLLLPGPVLGLLALRPLWSRSRSGAG"
     gene            24309..24713
                     /locus_tag="P5537_01860"
     CDS             24309..24713
                     /locus_tag="P5537_01860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76818.1"
                     /translation="MMKPCKRAFVALALLVLALPAWTQAVVEDAPMLRLDCGGIGLEE
                     SERMRAEVGMHALTVFFSTTGGGWVTDVETQVDEPLSGQRVEASCGPIGQVDVPTPGR
                     YRISASYAGERQEHWVDLVPQGGARLSLRWQE"
     gene            24819..26126
                     /locus_tag="P5537_01865"
     CDS             24819..26126
                     /locus_tag="P5537_01865"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HRV76819.1"
                     /translation="MSVQRVLTGITTSGTPHLGNYAGAIRPAVAASRQPGVESFYFLA
                     DYHALIKTTDPLRVQRSTLEIAATWIAAGLDTDRVWFYRQSDIPEIPELTWLLTCVAG
                     KGLLNRAHAYKAAVDRNTAEGVDPDAGVNMGLYMYPVLMAADILMFKAHSVPVGRDQI
                     QHIEMARDMAGSFNHLYGEHFVLPEAAIDASVATLPGLDGRKMSKSYDNTIPLFVPTA
                     ELKKLIFSIVTDSKAPGEPKDADGSALFQLYQAFSTAEETRAMRTAFDEGIGWGEAKQ
                     ALFDKIEAAVAPMREHYLALIAEPARIEKHLHEGAAKARAIATPFLAELRHAVGLRNL
                     ASVPQAARAAKAKAALPQFKQYREADGRFHFKLVDADGRLLLQGAGFASPREAGAAVA
                     ALKQGAAFEMRDGVLWLEGAQVATLAEGVDEADLRAALGTFAD"
     gene            complement(26168..27019)
                     /locus_tag="P5537_01870"
     CDS             complement(26168..27019)
                     /locus_tag="P5537_01870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018990504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HRV76820.1"
                     /translation="MMNLPTELLRTFIKAVDLGSFTRAGDAVGRTQSAVSLQMRRLEE
                     MLDTQLVERGTHRVKLTEEGATLASYARRMLALNDEAVASLQRSRVAGSVRLGAPHEY
                     MASLLPTILGKFAQSHPGVTLEVTCDLSKNLLERQQKGEFDLVIALHDQGQASGGVQV
                     HTEPLVWITSADHTRHEQQPLSLVLAPPPCIYRNRILQTLGRLNRSWRIAYTSSSYSG
                     IIAAVRAGLGVTLLAESTVPAGVRTLGAREGFPEMGLLDVCVHRSRENASEAAECLAE
                     YVAGSFS"
     gene            27151..27519
                     /gene="gcvH"
                     /locus_tag="P5537_01875"
     CDS             27151..27519
                     /gene="gcvH"
                     /locus_tag="P5537_01875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004371636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HRV76821.1"
                     /translation="MSILKFTEDHEWLRVEGDVATVGITDYAQNALGDIVFVQLPDVG
                     ASFARGDEAAVIESVKAAGELKMPLAGTVVEVNPALVDAPATVNEDPLGAGWFIRVRL
                     DDPSAAEALLDQAAYEKLTA"
     gene            27575..30457
                     /gene="gcvP"
                     /locus_tag="P5537_01880"
     CDS             27575..30457
                     /gene="gcvP"
                     /locus_tag="P5537_01880"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004375 - glycine dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase"
                     /protein_id="HRV76822.1"
                     /translation="MNIHDIRFPATLAQLEQRDDFVGRHVGPDGAETRAMLDVLGLDS
                     LDQLIDKVIPAAILSAAPLALPEGRSEPEALAMLRAIAGKNRVLRSFIGTGYHDTFTP
                     TVILRNVLENPAWYTAYTPYQPEISQGRLEALLNFQTMVTDLTGLEIANASLLDEATA
                     AAEAMAFCQRLSKSKAKAFFVSRDCHPQTIEVVRTRAEPLGFEVIVGDAATELAAHEV
                     FGVLLQYPASTGEVVDYAAIVAAAHDRKALVVVAADLLALTLLKPPGEFGADVAIGST
                     QRFGIPMGFGGPHAAYFATRDEHKRVMPGRVVGVSIDSHGKKAYRLAMQTREQHIRRE
                     KATSNICTAQALLAIMASMYACYHGPDGLTTIARRVHRLTATLAAGLRRLGVDVPTTA
                     FFDTITVRVADAAAVHAAARAAGMNLREIDAGTVGISLDETTRRADVEALWAVFGTGA
                     AALDFAAVEAQVQEALPAAQLRSSAFLTHPVFSAYRSETRMLRYLRSLADKDLALDRT
                     MIPLGSCTMKLNATTEMIPVTWPEFGALHPFAPADQTAGYAQLTAELEQMLCACTGYD
                     AVSLQPNAGSQGEYAGLLAIRAYHASRGEGHRDVCLIPSSAHGTNPATANMAGMRVVV
                     VACDTNGNVDVADLKAKAAQHAEQLAAIMITYPSTHGVFETAVREITDIVHAHGGQVY
                     IDGANLNAMVGLCGPGQFGGDVSHLNLHKTFCIPHGGGGPGVGPIGVKSHLAPFLPGH
                     AAVGLEGIGAVAAAPWGSASILPITWTYITLMGRDGLRHATVMAILNANYIAQRLEPH
                     YPVLYRGENGLVAHECILDLRPLKDSTGVTVDDVAKRLMDFGFHAPTMSFPVPGTLMI
                     EPTESESKAELDRFCDAMIAIRAEIAKVASGEFDARDNPLVNAPHTAEAIAGEWTHPY
                     SRELAAYPVASLRGNKYWSPVGRVDNVYGDRNLVCACPPMSDYEQA"
     gene            30470..30994
                     /locus_tag="P5537_01885"
     CDS             30470..30994
                     /locus_tag="P5537_01885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004371642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HRV76823.1"
                     /translation="MNVSFIVTLVGEDRPGLVSALAERAAANGANWLDSSMAHLAGKF
                     AGIVRLDVAEADADRLEAALRALSSTGLSLSIERGTAAAGTAGGELIRMELLAHDRPG
                     IVRDISSVLARHGASIERMDSACESASFSGEAMFRAELEVRVPASVSAGEVQAALESL
                     ANELMVDLKLETGA"
     gene            31087..32340
                     /gene="glyA"
                     /locus_tag="P5537_01890"
     CDS             31087..32340
                     /gene="glyA"
                     /locus_tag="P5537_01890"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HRV76824.1"
                     /translation="MFDKQMQIAGYDDALWQAIEAERARQEDHIELIASENYASPRVM
                     QAQGTVLTNKYAEGYPGKRYYGGCEHVDVVEQLAIDRAKQLFGADWANVQPHSGSQAN
                     AAVYLALLQPHDTILGMSLAHGGHLTHGAKVNFSGKIFNAVQYGVTDDGVIDYDALEA
                     QALECKPKMIVAGFSAYARHLDFPRFRAIADKVGALLFVDMAHVAGLVAAGLYPNPVP
                     FADIVTSTTHKTLRGPRGGIIVGRANPDIEKKIASMVFPGTQGGPLMHVIAAKAVAFK
                     EALEPSFKEYQQQVIANARAMAGVFVERGYKIVSGGTDDHLFLVDLIAKGITGKAADA
                     ALGAAHITVNKNTVPNDPQSPFVTSGVRIGTPAATTRGFGVAEVTALAGWICDILDDI
                     DNPAVIDAVRAKVSALCARFPVYGR"
     gene            32409..33542
                     /gene="gcvT"
                     /locus_tag="P5537_01895"
     CDS             32409..33542
                     /gene="gcvT"
                     /locus_tag="P5537_01895"
                     /EC_number="2.1.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004371648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004047 - aminomethyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006546 - glycine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system aminomethyltransferase
                     GcvT"
                     /protein_id="HRV76825.1"
                     /translation="MSDHDATAQMLRTPLYDLHVSLGARMVPFAGYEMPVQYPAGILK
                     EHIHTRSQAGLFDVSHMGQVMLVGADAAAALETLVPVDIVDLPAGMQRYALFLNDQGG
                     VMDDLMVANFGDGRLFVVVNAACKAQDIAHMQQHLSARCKVEVLADRALLALQGPAAG
                     AVMARLAPATANMVFMNTATVTLVGAECYISRSGYTGEDGFEISVPADKAEALAKELL
                     SHPEVAPIGLGARDSLRLEAGLCLYGHDLDQNTSPVESSLLWALSKVRRADGARPGGY
                     PGAAVVFEHIAKGVARKRVGLRPTARVPVREGAELVDADGRKVGVVTSGGFGPTLEAP
                     VAMGYVETALAKPGTQLAAMVRGKPVPVEVASTPFVPQRYYRG"
     gene            33686..34432
                     /gene="ydfG"
                     /locus_tag="P5537_01900"
     CDS             33686..34432
                     /gene="ydfG"
                     /locus_tag="P5537_01900"
                     /EC_number="1.1.1.298"
                     /EC_number="1.1.1.381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional NADP-dependent 3-hydroxy acid
                     dehydrogenase/3-hydroxypropionate dehydrogenase YdfG"
                     /protein_id="HRV76826.1"
                     /translation="MIVFVTGASAGFGAAIARSFVKGGHRVVATARRKDRLDALAAEL
                     GDALLPIELDVRDADAVAAVPGALPAGFAEVDVLVNNAGLALGLEPAHQASLDDWHTM
                     IDTNCTGLVQVTRAFLPGMVARNRGHIFNLGSVAGRWPYAGGNVYGATKAFVRQFSLN
                     LRADLLGTALRVTDIEPGLCGGTEFSNVRFHGDDDKAARVYADVQPLTAEDIADSVYW
                     IATRPAHVNINTIELMPVAQSFAGLSVHRG"
     gene            34702..37758
                     /locus_tag="P5537_01905"
     CDS             34702..37758
                     /locus_tag="P5537_01905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HRV76827.1"
                     /translation="MPAPPGRRLHPRQVLGAAVFVALLVASVAGGLLLWHESATSRLQ
                     ARELARYAARLDYALVAGPSEAIRFPAHGPFDRRLGYTELARFAERLQARGFALVEQV
                     RFDDALLAHVERGLFPPYAEKTRAGLDVFDCRGEPLYGFRYPWRGYARFEDVPAIVAQ
                     ALLFIENRELLDESRPTLNPAVDWVRFARAALGQLGRMVDADLDAPGGSTLATQIEKY
                     RHSPAGITLDAREKLRQMVSASVRAYRDGEHTLPVRRRLVLDYLNTVPLSAAPGHGEV
                     NGLGDGLWVWFGADFERVNALLAAPEGEGDARIAQGQALRQVVALMIAHRRPSWYLAG
                     GREELARTTDAYLRLFAEAGLIGAGLRDAALARPLAFRDLVADPAWVPATPGKGTTAV
                     RTRLAGLLDTSLYGLDRLDAELGTTLHGGLQQAVGDYLGRLADPAFARSQGLIGERML
                     DPATLGAVRYSFTLVERTAGGNRVRIQTDTTDQPLDINEGSKLELGSTAKLRVLATYL
                     ELVAELHARLAVLDPPALRRVEVDGQDRLTRWAIDHLASTPDRSLPAMLEAALERRFS
                     ASPGEGFFTGGGRHSFGNFNAGDNAREPTLREALQASINLPFVRLMRELVRHTMYQVP
                     GSTARLLEDNDDPRRVDYLVRFADREGQLFLRRFWRKYQDSTPEEMRSTLLDGLRPGA
                     DRLAAVFRYLEPEAPPQALADFLARRLGEPPAAARLAQLYARNAPEAFDLPDRGYVAR
                     VHPLELWLVAFRLQHPEATLAEAVATSAEERQQVYRWLFRTRAKGAQDSRIFTLLEVE
                     AFLEIHRRWARLGYPFGHLVPSLATALGSSGDRPAALAELMGIIVNDGLRLPVQRIDT
                     VRFARATPYETAFAIRPVEGDAVMAPEVARALRGALSDVVEGGTARRLAGAFKLADGS
                     ELALGGKTGTGDNRIVVRGRAGLALNRTATFVFYLGPRHFGTLTAYVIGPEAASYRFT
                     SGLPVQILKSMGPLLIPHLEPARADACRPPPLSGGPESAPQPTPAE"
     gene            complement(37780..39579)
                     /locus_tag="P5537_01910"
     CDS             complement(37780..39579)
                     /locus_tag="P5537_01910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HRV76828.1"
                     /translation="MLLPELHAPLFVGLVLVVLFLAFVREWAKPDVAVMVAVGVLLAA
                     GMLNSKEVLGVFGNSAPITIACLFIISGALSRTGCVDQLGEWLAAAAGAGERRLLLAL
                     IAACLLVSPFINNTPVVMVMIPAVIAVAARQGLAPSRLLIPLSYATILGGLITMVGTS
                     TNILVDGVAREQGLAPFSMFEISLPAILMALVGSAFMLVFAPRLLPVRETLSQQFGAG
                     ERWFMTELFVPEGSHLAGRTLREARLSNGIIQVLNLVRGDTELADPAPDTRLEVGDRV
                     VVHSRSDAMMALRSSDGVGLQAPAGTATHDVETLRRRDLVMVEAIVGQTSRYILRPIR
                     DLDLLARYGIHLVAVHRRDASFAQIGEDFQLLGGDVLLVEGTPAQFQRFCDNGDLFAI
                     TEGRQMTSRRHKAPVALATIVGVMLLAALNVMPIEGLALIGAAIVIATGCLTSDEAYK
                     SIEWPILVLIFGMLAISIAMRNSGLDQLLAGQLAALGEGMSPWLMLSLVILITSVATE
                     ALSNNAIAVLFTPVAIGLAQQMGVDPRPFVVGVMFAASCSFATPIGYQTNTLVYSAGN
                     YRFADFARLGVPMNVLTWLLCSVLIPLFWPFHP"
     gene            complement(39721..40653)
                     /locus_tag="P5537_01915"
     CDS             complement(39721..40653)
                     /locus_tag="P5537_01915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HRV76829.1"
                     /translation="MRLTFHQLRLLLAVSREGSVSRAAQRLHLTQPTLSAQLRQLAEQ
                     VGLPLFERVGRKLHLTAAGRVVLDTANRVEQELERLDETLAELRGDVVGRLRLAVVST
                     AETFIPRLLGDFRRERPAVEVSLVVLNRDAVIRRLADNLDDLYIMSRPPQAPPVVATP
                     FLSNPLVVVASTEHPLAGCRRKLPLEALADEEFVLREPGSGTRQAVEQFFATHGLALR
                     PRLELGSNEAVKQAVAGGLGLSLLSAHALAHAVDEGIAVLRVDGTPLPTQWQVVYPAG
                     KRLTPLAGAFLEFLRERAAELERSAQERLDAARR"
     gene            40844..41785
                     /locus_tag="P5537_01920"
     CDS             40844..41785
                     /locus_tag="P5537_01920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent bicarbonate transport family
                     permease"
                     /protein_id="HRV76830.1"
                     /translation="MVDAVPFFFALGAVASLARSGLRLPAAVFETLSIYLLLAIGLKG
                     GVEIARSESATLWVDALLAIGLGAVIPLLVFPLFRLRFSRPDAASLSAHYGSVSIVTF
                     AVGAAVLAGRGIEVEGHLALLAALMEAPALIVATLIARWGVKSADGSSTAGALVHEVF
                     ANKSVVLLGGGILIGWVAGPQGLEPLSPLFVDLFKGALCLFLLEMGLIAADRLPDLKK
                     AGLFLVGSALALPPVLALAGWGVAQLMGLGVGGTVLMMTLAGSASYIAAPTAMRIAVP
                     EANPALGVAAALAVTFPFNLLLGIPLYLWWAQTMAGA"
     gene            complement(41724..43274)
                     /locus_tag="P5537_01925"
     CDS             complement(41724..43274)
                     /locus_tag="P5537_01925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002928839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HRV76831.1"
                     /translation="MLPTLVPIGALLAGIALLLLGSGLLNTVVSLRGNLEGFSETTLG
                     LIGSTYFLGFFLGTFVAPKLIRRMGHIRAFAFFGATVAACILLHALVVHPWFWMGLRV
                     LTGMSLVGFYAVIESWLNDQTAPERRGQVFAAYMIVNLAALAGAQQLLRLDTPASFTL
                     FAVAAMFVCLSLLPVTMTRFPQPQIATRVRLRLRMTWRAAPAAYVGALSSGLSMGAFW
                     SLTPVYGERVGLDEAGIGLLMTAAIVGGALLQWPMGRFSDAGDRRLALSVAAFGAALA
                     AVAVALFGHVEHVPLAGLFLYGGMAFAVYPIVVAHLIDHLPQDQILAGNTTVLFLHGV
                     GAAVGPGIAGALMGWVGTIALPLHLGLAFVPLGLFALLLSRRSEDEIVEEAAQFTPMM
                     RTSHTVLEMVSPEGAEADAEAAEGAGVEATDVADTDVPPPAADVVEDVEAPAVLAPLE
                     DTAAAPEAQTADREGEEDAPACGGAESQTAAEATLPPPPVADPGALLRPPPSSAPTTG
                     TAGSRAAD"
     gene            43600..44082
                     /locus_tag="P5537_01930"
     CDS             43600..44082
                     /locus_tag="P5537_01930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PACE efflux transporter"
                     /protein_id="HRV76832.1"
                     /translation="MSAKPKLRTFPDRLRQIAMFEIGGLLLVTPPFAWASGVPIRESI
                     GLLALLALMAAIWNGAYNTTFDWIEGRLTGRTADRRPFRLRALHALGFESGLLLMTLP
                     VIVWWTGMGWVEALIADIGLAITYTIYAFLFNLGYDRLFPIAPADGNAAAAAGLAAER
                     "
     gene            44084..45136
                     /gene="murB"
                     /locus_tag="P5537_01935"
     CDS             44084..45136
                     /gene="murB"
                     /locus_tag="P5537_01935"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HRV76833.1"
                     /translation="MTAAGCSPRVDADSQVVADADLSALNTFGLRARAARLLRVRSVE
                     TLRAAIAAPGWTETPRLVLGGGSNLVFGGDFPGTVLRVEIPGRRLLRSDAEAWIVEAG
                     AGESWHDFVRWTLAQGWPGLENLSLIPGTVGAAPIQNIGAYGLELVERFESLDAVELD
                     TGELCRFDAAACAFGYRDSVFKRNPGRWMVVAVRFRLPRPWRALTRYADVARELEARG
                     LAQPGALEVSDAVIAIRRRKLPDPAVLGNAGSFFKNPVVDAARCARLLAEHPALPHYP
                     QADGSEKLAAGWLIEHAGWKGRDLGPVGCYERQALVLVNRGGATGDDVRRIAQAIIAD
                     VDARFGVRLEPEPVFI"
     gene            45213..46607
                     /locus_tag="P5537_01940"
     CDS             45213..46607
                     /locus_tag="P5537_01940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HRV76834.1"
                     /translation="MSQEPGRSAVLDELRTAFGADEVLAGNASPRHLKDWSTASGGTP
                     LAILRPRSTAELSRMLAICNTHGQAVVPQGGLTGLVGGAVPGEGQVVVSLERMNAIEE
                     IDLGSGTVTVQAGAVLQTLQEACHEAGALLAIDLGARGSCQIGGNVSTNAGGNRVIRY
                     GNTRESVLGLEAVLADGTVLPMMNRMAKNNAGVDLKHLFIGSEGVLGIVTRVVLKLHP
                     LPRGTSTALVALADFDAALSFLRHAQQSLSGQVSAFEIMWREYLDVAVATNHLRRPFA
                     ADYPVYVLTDMHCGQPETDARRFETMLEQAIESGWVLDAAVAQSMADAEALWAIRDGI
                     AEVLRERAPTLNFDVSVPVGRIGECVARMRANLERGWPQLQALFFGHVGDGNVHVVVC
                     KVPQDADSLHSIEEAVYGVMRDYGGSVSAEHGIGVLKRDWLAYSRTPAELALMRTLKT
                     ALDPRGILNPGKML"
     gene            complement(46628..47374)
                     /locus_tag="P5537_01945"
     CDS             complement(46628..47374)
                     /locus_tag="P5537_01945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar brake protein"
                     /protein_id="HRV76835.1"
                     /translation="MSEDTSNAELRDDEHADGQDEVEAQRGFTFEDMRLAVGDRLQIE
                     CTASTGVWRAFVRVVGYMDGVSLLVTTPVAGGRRVELVENDPVIVRVFSRQSAFAFRA
                     SVLRACKLPFDYVHLSFPTVIQGSVIRKSTRVRTQFPVGLSSPTGGEPSEGTMLNLSA
                     TGALIHTRAALGEQGSIIRLRFDVILHELHSELDIAAEIRNVQQEPDAEGEGIEYHYG
                     VDFHELGAEDRMKIKSLVYQTIIEQPRRII"
     gene            47593..48447
                     /locus_tag="P5537_01950"
     CDS             47593..48447
                     /locus_tag="P5537_01950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76836.1"
                     /translation="MYKMTKLRSLPALALACALVATSGASQAVTWSDTFVGYRHGSEF
                     HEPNNPRDVEKHIVQFSHASGYTMGQNFLNLDIFRSDEADPTVRGGDKGATEFYLVYR
                     HQLHLGKALGKRFAFGPVKELALTAGFDLNTKDSPVQPRKRVLVAGPTLKFDVPGFLD
                     VSLLFGREWNQNKLGSPKQRIAFDPQWILNAAWGIPFTVGPVPLKFQGFANHLSKRGE
                     DYNGRKTKAETLMRAALMVDVGQMVSGRKNTFLMGVGYEYWRNKFGNHGIPGVEVDAP
                     TFQAEWHF"
     gene            48661..49551
                     /locus_tag="P5537_01955"
     CDS             48661..49551
                     /locus_tag="P5537_01955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76837.1"
                     /translation="MTRLSTRIQTLAAAGALLAMPAAGQAATWSDTFVGYRYGSDFRE
                     PTNTKDVDKHVLQFTHASGYSVGQNFVNLDVLQSDKADPASGGASGATEFYLTYRHQV
                     HLGKAFDRSFAFGPVKEVAVTAGFDLNTKNTAFSPRKRLVVLGPTLKFDVPGFLDVSL
                     LVGKEWNRCGLDPVAPSTFDPCPKTEVSFDPQWIVSAAWGIPFSAGPLPLKFQGFINV
                     NGEKGKDYAGVKTHTETLMRTSLMVDVGQMAWGRKNTFLMGVGYEYWRNKFGNHAYAN
                     GVEKPGIDTNAPTFQMEWHF"
     gene            complement(49640..51076)
                     /locus_tag="P5537_01960"
     CDS             complement(49640..51076)
                     /locus_tag="P5537_01960"
                     /EC_number="1.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HRV76838.1"
                     /translation="MTYPDTRLLIDGQWCDALDGRTLAVHNPATGEEIGRVAHAAIAD
                     LDLAVAAAVKGFQAWRRTPAIERAKTLRRAAALMRERAGDIARLLTQEQGKPLPEAKM
                     ETLAAADIIEWFADEGLRVYGRIVPGRNLAATQMVIKDPVGPVAAFTPWNFPINQVVR
                     KAAAALATGCSILVKAAEETPAAPAELVRAFVDAGVPAGAIGLVYGTPAEISSYLIAH
                     PAIRKITFTGSTPVGKQLAALAGQHMKRVTMELGGHAPVIVCEDADLELAIKVSAGSK
                     FRNAGQVCISPTRFLVHEAVRENFAAALARHASTLKVGDGLAEGTQMGPLANSRRVAA
                     MADFVQDAVARGATVAAGGECIGAAGNFFAPTVLTGVPLDAKVFNEEPFGPVAAIRGF
                     TTLDEAIAEANRLSFGLAGYAFTGSLKNAHRLAHELEVGMLYINQPATPSAEMPFGGI
                     KDSGYGTEGGPEALDAYLNTRAVTVMNV"
     assembly_gap    51314..51413
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(51482..52633)
                     /locus_tag="P5537_01965"
     CDS             complement(51482..52633)
                     /locus_tag="P5537_01965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HRV76839.1"
                     /translation="MNRRNFLRAGSLAAGLALPALARARQPASAAVTAPLATPTPLAE
                     PPAFAPTPETGWRRFELVSRIEPLPGDGPLRVWVPLPAMHETAWQRPMGSLWQGNAEL
                     MERVRDRSGAEMVYAEWAPGVAQPQLEILSRFATRDRATDFTQPSAEPQRLTRAERML
                     YLRPTALLPTDGIVRDTARDIVQGAKGDEDKARAIYDWIVDNTFREPKVRGCGIGDIR
                     SMLETGNLSGKCADLNALFVGLARAAGLPARDVYGIRVADSRFGYKSLGKSGNVSKAQ
                     HCRAEVFLERFGWVPVDPADVRKVVLEEPPGKLSMVDPKVAAVRRQLFGAWEMNWLAY
                     NDAHDLRLPNSTGKEIPFLMYPQGELAGQRFDSLDPDAFSYTLSAREIS"
     gene            53067..53792
                     /locus_tag="P5537_01970"
     CDS             53067..53792
                     /locus_tag="P5537_01970"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HRV76840.1"
                     /translation="MNQPIPGTASCCPVCLGASVRPFLHAGGRDYLRCEACEATFLHP
                     AQRPAADVECAEYRLHRNDPGDPGYRRFLARLVDPLRARLAPAAQGLDYGCGPGPALA
                     AMLREAGHPMRVWDPFFAPDPDALARRYDFVTCTEVVEHFHAPAAEFARLDGLLRPGG
                     WLGITTCLQTEDARFAAWHYRRDPTHVVFYRAATFRAIAARFGWRCELPAKDVVLMHK
                     PAPPVAAATAASSPPPNPDRESP"
     gene            53789..54571
                     /locus_tag="P5537_01975"
     CDS             53789..54571
                     /locus_tag="P5537_01975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HRV76841.1"
                     /translation="MSYETLLYDLSDGIAEIRLNRPQRLNAVTQQLYDELNDALGRAE
                     AAREARVVLLTGEGRAFCVGADLKEHKVGRTAFDRRQYLKGEQDVCRRLIDLQKPVVA
                     AVNGYALGAGAEMALASDFLLMAEGAQLGLPEISIGNFLGGGVTWLLPRLVGLAKARE
                     LVFLGERVGGEEAVRIGLANRVFADAGFLDEARAFARRIAAKAPFSMELAKRQLNLSA
                     ERTLDACLTAELEGMMFVGTTRDWQEGVDAFAEKRAPVFKGE"
     gene            54573..56759
                     /locus_tag="P5537_01980"
     CDS             54573..56759
                     /locus_tag="P5537_01980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HRV76842.1"
                     /translation="MSENPSPVPCSPARRSPLHDFLAPASIAIVGASADPTKRGYKAM
                     VGLIKGDYRGRIYPINPKVPEILGVPTCATLDDVPGPIDLALICTPAKTLPGLLEECG
                     RKGVKGAVILASGFRETGPEGARLEQQVLDAARAGGVRIIGPNTSGMFNLHHKVNLLD
                     LRNARPGDIGFISQSGNMLLALVLEAEHNGHVGFSTYVGPGNQTDVGFNDYLRYLGED
                     EHTRVATLYVEGFRDGQRFLEAAREITPVKPVVVYKSGATELGKKAASSHTGALAGSY
                     AMTVDLLRQVGVSVVHHSDEILPVAEGLALMQQARGRRVAVIADGGGQATITSDRLSE
                     SGLELAELSEATRKRLAAILFAQASLANPVDVAGSSDADPEVLARCVEIVADDDNVDA
                     VFLVGMFGGYHTRFAESLLGGEMRAAEAMIELARASAKPLVVYSLYAPVKPPALRRLH
                     EAGLPVYASIEQAVKVLQALAERGLYLQDRHGQPLQAGVAPDEAMQAMFARAQNEGRD
                     LYEHEARALLRTHGVAVADELVAHTADELGAAIERFGDQPLAMKVVSKDILHKSDAGG
                     VKLNLVGEAALREAYDQIMASCRAYDPGADLRGVLLTPMARKGVEVIVGVVRDPIFGP
                     VLMFGLGGIFVEILEDVAFRAIPLSRRDAETMVDQLKARKVLAGVRGEPPVDKAALVE
                     LLLKVSSIVSAYPQLSELDLNPVIAYADGYAVVDARIIANRAVASS"
     gene            57082..58935
                     /locus_tag="P5537_01985"
     CDS             57082..58935
                     /locus_tag="P5537_01985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HRV76843.1"
                     /translation="MARKRRSTIFWVIGLAFIGLVFDGYDLVVYGAVLPGFMGPDAAK
                     WIGDRALTPQEAGMLGSYAMVGMMLGALVAGTLGDLIGRRKVMIASIAWFSIGMAVSA
                     MTESVTAFGIWRFITGLGVGALAGTTGAMAAEFAPPGKKNLATAFTYAGIPLGSLLSA
                     LLAIFLLPVIGWRGMFLLGALPLVTLLPLAIWKLPESVAWLASRGRLDEARRVSERTG
                     VPIPETEIKPQHSAAARSSDERAGWAGLFTVYLVPAIVIGFVSAFCLLLVYSLNTWLP
                     KIMLPIMGQNGSLALLLVLNAGAMVGTLYGSTLADKHSPQRIVALGFLVGALAMGAIG
                     MIASTIDVPAVAKAGEVQQLADVGGIVVALLLLTIAITGLGTSGTQTLIYGLAANYYR
                     TNVRGAGVAWTAAFGRIGGIFGPIFGAFLAVKFAGELHSIFYVLGGISLIGLALTLII
                     PKSKAAAAVQAVAPTTAPAAAVPDGKSRLYGTIMAVVDHTGNKLTRARVSEFVSLTGS
                     KVHLVYLAPEHVLSAEVDQTDKTIDPRHVANLQEYVNEVNAQGVPAEGQILTSTLFGR
                     GKAVVDLAEQLRCDLIILNTEEGGQRAKAELAQEVAGQNPKMAVLIARSTQ"
     gene            59304..60659
                     /locus_tag="P5537_01990"
     CDS             59304..60659
                     /locus_tag="P5537_01990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid/H+ symport family MFS transporter"
                     /protein_id="HRV76844.1"
                     /translation="MRNVDVHRTIDEARFNRFHLNVLFWCALVIIFDGYDLVIYGVVL
                     PVLMQEWNLTPLQAGSLGSAALFGMMFGALIFGPLSDRIGRKKVIMITVVIFSGVTFL
                     NGFAQTPTQFGVMRFIAGLGIGGVMPNVVALMTEYMPKRIRSTMVAVMFSGYSVGGMT
                     SAFLGMYLMPSYGWQSVFFVAGIPLLLLPLIWIFLPEAVGFLLKEGHKEEAGRLLARV
                     EPSYAPAAGDSFHLVTGKGRSVALVALFQNGRLVSTLMFWVAFFSCLLMVYALGSWLP
                     KLMNKAGYELGSSLSFLLVLNFGAIFGAIGGGWLADRFHLRRVLTIMFAIAALSISAL
                     AIRNDMVVLYLLVAIAGATTIGSQILLYAYVAQYYPLGIRSTGIGWASGVGRLGAISG
                     PMLGGALISMPLETNFLAFAIPGAIAGLAISMVGRSAVHAPEEEENLAFVGETGKLEV
                     D"
     gene            60809..>61806
                     /locus_tag="P5537_01995"
     CDS             60809..>61806
                     /locus_tag="P5537_01995"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HRV76845.1"
                     /translation="MELESYVRALPKAELHLHIEGTLEPEMMFALARRNGIALPWASV
                     EAVRAAYAFTDLQSFLDLYYAGAAVLVREDDFFELALAYFARAHADGVVHAELFFDPQ
                     THTARGVAFETVLDGLERACVEARRRWGIGARLILCFLRHLSEEDGFATLQQALPHLS
                     RIDGVGLDSSERGHPPAKFARLFARCRELGLHVVAHAGEEGPPAYIVEALDLLKAERI
                     DHGVRCTEDPALVERLARAQVPLTVCPLSNVKLCVFPDLASHNLGQLLAAGLKVTINS
                     DDPAYFGGYVAKNYIDTARALGLGRAELRRIARNSLEASFVSAAERAPWLARLDALG"
BASE COUNT         8925 a        21739 c        21469 g         9473 t
ORIGIN      
        1 gtcgccgcga tgaacccctg tccctgcggc cacctcggtg acccgcgccg tgcctgccgg
       61 tgcacgccgg atcaggtcgc gcgttaccgc ggtcggctgt cgggcccgct gctcgaccgc
      121 atcgacctca ccgtcgaggt gccggcgatc gcgcccgagg cactgttcca gagtccgccg
      181 ggcgagccct ccgccgcggt gcgcgcgcgg gtggtcgccg cgcgtgcgct gcaggcggcg
      241 cgccagggct gtcccaacgc ccgcctgccg gccggcgagg tggagcggca gtgtcgcccc
      301 gatccgggtg gcgagaccct gctgcggcag gcgatgcagc ggctcggcct gtcggcgcgg
      361 gcgtatcatc gtgtcctgcg cgtcgcgcgc acgctcgccg atctcgccgg cgcggagcgc
      421 ccgggggccg cccaggtggc cgaggccatc cagtaccggc gcagcctcga cacgcgctga
      481 acgaatcggc gcgtctcgcg tctccggcgc cggacaacaa catcaagaat ccgcctcaag
      541 gcgcacatga cccgaccgct cacccatgcc cgcctcgcct cgctgctggc cgccctgtcc
      601 tcgatcggcc cgttcgcgat cgacgcctat ctgcccgcct tccccgcgat cggcgcggcg
      661 ctcggcgcca gccagctgga ggtgcagcag accctgacga tctacatggc cgcgctcgcc
      721 gccatggtgc tctggcatgg cgccctcgcc gaccgcttcg gccgccgccg cgtgttgatc
      781 gcgctgaccg tggtgtttgc gctcgcctcg ctggtgtgcg cgctggcacc gagcatcgag
      841 tggctctggg tcgggcgcgc gttgcagggt ctgagcggcg gagcggggat cgtggtcgga
      901 cgcgcggtgg tgcgcgacct gcacgagggg ccgcaggcgc agcgcctgat gtcgcgggtg
      961 atgctgatct tcgcgctcgc accggcgctg gcacccctgg tcggcgcggg cctgctcgcg
     1021 ctcgcgggct ggcgggcgat cttcctcttc ctgaccctgt tcggcttcgt gctcgcgtgg
     1081 gtgacctggc gcttcctgcc cgagacgctc gccgaggagg accgccagcc gctgcatccg
     1141 ctggcgctgc tgcgcgccta cctggcgatc ttccgccacc cgggcttcct gctgctggcg
     1201 ctcggggtgg cgctgaactt caacggcttc ttcctctatg tgctgtcggc gccggtcttc
     1261 atcctcgagc atctgggcct cggcagcggc ggcttcgtgt ggctgttcgg tccggcggtg
     1321 ggcgggatga tgatcggctc gatgctctcc gagcgcatgg ccgggcgctg gtctccggtg
     1381 cgtacggtcg gaacgggctt cgtgctgatg ttcgccgcgg tcgtcgccaa cgccgccgtg
     1441 tcgggcctgt tcgcccccgg ggtgccgcgc tcggtgctgc cgatcggctt gttcagctgc
     1501 ggcatggcgg tggcgatgcc gagcatgagc ctgctcgggc tggagctctt ccccgagcgc
     1561 cgcggcatgg cgtcgagctg ccagagcttc ctgcagatcg gcttcaacgc cgcaagctcg
     1621 gcgctggtgg cgccggcgct gtggtcgagt ccgctcgggc tggcttcggg gatgggcatg
     1681 ttcgccgcgc tcggcctgtg cacctggtta gcgtggcggc ggctggcagg gcgcgggccg
     1741 gcgacggcac ggcttggcga gatggcgccg cggccgtagt ggttggccct tatttttgtc
     1801 gtggacgcct tcggctaagg tcacgcctca ttctagaatc ctgagtttgc gggctgcccg
     1861 ggccgtggcg ctcgtgtgcc cggactccgc tcctcccgct cctctcgccg caaggaatcg
     1921 caacgctatg ctcgaagtgg atggcctcgt caaagccttc ggcggcttcc gtgccgtcga
     1981 cggctgcacc ctgcgggtgg gcaagggcga gatcctcggc ctcatcggcc cgaacggcgc
     2041 gggcaagacc acgctcttca acctcgttgc cggtgccctg cagccgaccc tgggaacgat
     2101 ccgctttctc ggcgaggaca tcaccgcgct gccgaccgac gcgcgcttcc acaagggcct
     2161 cgtgcgcacc ttccagatcc cgcacgagtt ccacaacctc agcgcgcgcg agaacctgat
     2221 gatggtgccg ccccgccagc cgggcgaaaa cctcttcgcc aactggttcg ccgccggcaa
     2281 ggtgcgtgcc gccgaggagg cggtgcggaa gaaggccgat gacacgctcg ccttcctgga
     2341 gctgacccac gtcgccgacg agcgtgcggg caacctctcc ggcgggcaga agaagctgct
     2401 cgagctcggc cgcacgatga tgaccgaggc gaagctggtg ctgctcgacg agcccgcagc
     2461 cggcgtcaac cgcaccctgc tgcgcaagct cgaggagaag atcctcatcc tcaaccgcga
     2521 gcgcggctat accttcatcc tgatcgagca cgacatggag atgatcgaga agctgtgcga
     2581 cccggtggtg tgcatggccg agggcaaggt gctgatccag ggcgacttcc agaccgtgcg
     2641 ctccgattcc cgcgtgctcg aggcctacct cggcgagacg ccgactgcgg tcgagcgcga
     2701 ggccgccgag cacgacccca aggtggagga actgcgcgag caggaactgc accgggagga
     2761 cctgtgatgg cgctcctcga catgaaggac gtgcgcggcg gctacggcga cgccgacatc
     2821 ctgcacgggg tgtcgatgac ggtcggcgag cgcgaggtcg tggtcatcgt cggccccaac
     2881 ggcgcgggaa aatccaccgc gatgaaatcc gtgttcggcc tgctcacgat ccgtggcggc
     2941 agcatcgtct tcgacggcga ggacatcacc ggctgggcgc ccgaccgcat cgtgcagcgc
     3001 ggcatctgct acgtgccgca ggtggacaac gtgttccgcg agatgacggt gcacgagaac
     3061 ttcgagatgg gcgccttcct gcgccgtggc gacctctccg ccgcctacga ccggatctac
     3121 gggctcttcc ccgacctcaa ggccaagcgc cgcaacctcg ccggcgacct ctccggcggc
     3181 cagcgccaga tggtggcgat ggggcgtgcg ctgatgctcg accccaagct gctgctgctc
     3241 gacgaaccca ccgccggtct ttcgcccaag tacatggaac agatcttcca gatcacccgc
     3301 gacgtgcgcg acgccggtgt ctccatcctg ctcgtcgagc agcacgccaa gcaggcgctc
     3361 gccttctgcg atcgcggcta cgtgctcgcc accggcgcca accgccacga gggcagcggg
     3421 caggccctgc tcgccgatcg cgaggtggcc gaaatgttcc tcggcggctg agggagtccg
     3481 gcgcacatga gcttcctgga attcctcaac ttccacctcg tgccgggcgt cgtgctcggg
     3541 tcgatctacg cggtgggcgc gatcggcatc acgctggtgt tcggcatcct gcgcttcgcc
     3601 cacttcgccc acggcgacat ggccacgctc ggcgccttcg tcgcgctcgc gctggtcact
     3661 gccgggctca ccccctgggc ggcgctgccg atcgcgatgg cggcggtggc ggtggtggcg
     3721 atcgtcgtcg acaagttgtt ctacgactac ctcaaggcgc ggcccaagat catgaccgtg
     3781 atggcctcgc tcggtgtcgc gctgatgctg cgcgcggtgg ttcaggtggt gttcggcgtc
     3841 gatccgcgca cctacgccac cggcatcgtg cgcccggacg agtatttcgg catcctgctg
     3901 cgcgaccgcg agctctacac gctggccgcg gtggtgctgc tcgtggtcgg gttgagcctc
     3961 ttcctgcgtc actcgcgctg gggcaaggcg atgcgcgcga tgtcggacaa ccccgacctc
     4021 gcgcgcctgt cgggcgtgga caaccgcaag gtcaccatgc tgacctgggc gatcgtcggc
     4081 gcgctgtgcg cggcctcggg cttcatgctc ggcatcaaca acgagctgca ctcgatgatg
     4141 ggctggcagg tgctgctgcc gatgttcgcc gcggccatcc tcggcggcgt cgggagggtc
     4201 gagggcgcgg tgctcggcgg cctgatcgtg ggcatcgccg aggagatgtc gatcttcatc
     4261 ctgccggcgc agtacaaggc ggccaccgcc ttcgtgctgc tgctgctgat cctgctcgtc
     4321 cgcccgcgcg gtctgctcaa cggcaaggtg ctctgatgga tctgctcggt ctcgccaact
     4381 acgcggtctt catggccatc ctgatcggca tctatgcgct gctcgcgctc gggctgaaca
     4441 tccagtgggg cttcaccggc ctcttcaacg ccggcatcgc gggcttcttc gcggtcggcg
     4501 cctacacctc ggccatcctc accagcctgc ccgcgagcgg gcggctgggc ggctacgaac
     4561 tgccgctgct gctgggctgg gcggcgtcga tggtcgcggc ggcggcgatc gcctggccga
     4621 tcggcaagat ctgcctgcgc ttccgctccg actacctcgc catcgccacc atcggcatcg
     4681 ccgagatcat ccgcctggtg atccgcaccg agggctggct caccggcggc gtgcgcggcg
     4741 tcaccggcat cccgcgcccc ttcggcgagc tcgactacat gccctcgcag atcgcctacc
     4801 tggccatcgt cgccacgctg gtgctggtgg cctacctgct cgtcgagcgc caggtgaagg
     4861 cgccctgggg tcgcatgatg cgtgcgatcc gcgacaacga actcgccgct gcggcgatgg
     4921 gcaagcaggt cgaggcgcgc cggctgcagg ccttcgtgtt cggttcggcg ctgatggggc
     4981 tggcgggcgc gctgttcgtg cacttcaacc gctcggtcac gcccgaggcg atcgacccga
     5041 tgatcgccac cttcctgatc tggatcatgc tcatcctggg cggctcgggc aacaaccgcg
     5101 gcgccatcct cggcgcggca gtcatctgga tcatctggtc ggtgtccgag ctgctcaccg
     5161 accgcctgcc caccgagatc gcggtgcagg ccaagtacgc gcgcgtgttc atcatcggcc
     5221 tgaccctgca gctggtgctg cgcttccgcc ccgagggcat cctgcccgag cgccagccgg
     5281 gctcgccgcc gcatcgctga ggtgcgcgcg acaacaacca gaacttcgtg gcgggcccgc
     5341 ggcgcgggcc tgcatcgtcc atcaggtgct tcggcacatt caggaggtga caaggtgaac
     5401 aagaaagcaa tcgcaggtct ggtcggcgcc atgctcggtg ccgcggtcgt cgccgcaccg
     5461 gcccacgccc aggacgtcaa gctcggcctg atggcggcca tctcgggccc gatcgcggcg
     5521 ctcgcgccgc cgatggcggc ggcctcgaag ctggcggtgg cgcatgtcaa cgagcagggc
     5581 ggcatcctca agggcggcaa gctcgaggcc gtgctcggcg acagcgcctg caacccgcag
     5641 aacgccaccg acgtcgccac caaggcggta aacatcgacc gtgtgctggc ggtggtcggc
     5701 ccggcctgct cgggcgcggt gctggcctcg gcgaactcgg tgaccatccc cgccggcgtg
     5761 ctcatgatca ccccctccgg cacctcgccc gagatcacca agctcaagga caaggacctc
     5821 gtctaccgca ccctgccgtc cgacgactac cagggccgtg cgctggcgcg cacgctcaag
     5881 gcgcgcggca tctccaaggt ggcggtggcc tacctgaaca acgactacgg caagggcctg
     5941 gccgaatcct tcaaggccga gttcgaggcc aacggcggca cgctcgccgg ttattcgggc
     6001 cacgaggaag gcaaggcctc ctaccgctcc gagctggcca cgctcgcgcg cggcggcgcc
     6061 gacaccctgg tcatcttcga ctatggcgac ggcaccggcc tgagcatcct gcgccaggcg
     6121 ctggagaaca acttcttcaa gaccttcgtc ggcgccgacg gcatgaagtc cgagggcctg
     6181 gtgaaggcga tcggcgcggc caacctcggc ggcttcttcg tctcggcgcc ggtgggcgag
     6241 gcctcggcct cgctcgacaa cttcaacaag gcttacaagg ccgctggcga gaacatcgac
     6301 gcggtgttcg ccaccacctc gtacgacgcc gccttcctcg ccgcgctggc gatcgagaag
     6361 gctggcggcg acaaggccaa gctcgcagag tcgctgcgcg cggtggcgag cgcgccgggc
     6421 gagccgatcc tggcaggcga gtgggccaag gccaagaagc tgatcgccga gggcaaggac
     6481 atcgactaca agggcgccgg tggcgaccac gagttcgatg ccgccggcga cgtgccgggc
     6541 aactacgcct tcttcaaggt cagcggcacg ggctacgagt cgatcgcgga catgaagtga
     6601 tcccggcccg cccgaatcgc gggcgggttc cctggcaatg caggccattc gcggctgccg
     6661 ccgctcctac aaaacccttc gttcagggct cgtgcaggag cggcggcagc cgcgaaccct
     6721 tgcagccgct gcgcacgatt gcaaagcgtc acctttcccc gattgcaaaa cgggtcgcca
     6781 tggtcgatcc ttttggcgtc gatccgctcc cggccgggct cgtgcttggc tggagggtgt
     6841 cccgacggcg cgctgcgcat gccgtcgatc aacggagagc caacatgaag cgcttcctcg
     6901 cctggatctg cgggctgctg tccgcgatcg gcatcaccgc ctgcgactac atcaacgtca
     6961 aggaactcca gccgggcgtg tccacgtcgg ccgaggtgcg cgagcgcttc ggtccgccgc
     7021 acatggagtg gcgcaacgag gatggctcgc tcacctggga gttcagccgc cagccgcagg
     7081 gcgtcgagtg cttcatgatc acgatcgggg ccgatcagat cctgcgccgc atcgaccagg
     7141 tgttgaacga ggagaccttc gccaaggtcc aaaacggcat gaacggcgac caggttcgtc
     7201 gcctgctcgg caagccggcc tccagccagt tcttccagct caagcaggag acggtgtggg
     7261 agtggaggat ctcgcacgga cccaacggca cgagcgatcc ggtcttcttc accgtgagct
     7321 tcaacaacga tggccgggtc acgggtaccg ggcgatatac gcagtacaag cactagacgg
     7381 gaggtcgaca tgtctgcccg cacgcacgct tctttgccca gcctgccgcg cgcggcaggc
     7441 tggttgctgc tcctgctggt cgccgcgatg ctggccggct gcgccagctt cgcgccgcca
     7501 cggccctaca ccaccgaagc cgaggcgctg tccgcacgcg gcgaacccac ccggcgctgg
     7561 agcaatgacg acggcacgac cacgctggaa tattccaccc agcccaacgg acggacctgc
     7621 ctgatggtcc aggtcgacca gggcgggatc gtgctgcgcc agtgggatgc gctcgccgcc
     7681 gagaacctcg ctcgcgtcga gcgcggcatg gacaaggagc aggtgtcgcg cctgctcggc
     7741 acccaccgct ccgaacagcg cttccgcaac tcgggcgagg aggtttggga ctggaacatc
     7801 cgcaacgacg gccccggcat cgcaacgctg ttcaacgtgc acttcatcga cggcaaggtg
     7861 gtgcgcacca gccagaccta tgtgtatccg cgagacggcg cggtcttcgg cggctggagt
     7921 ggctattacg gccatccctg gggttggggc atcggctttg gctatcccgg cccgttcttc
     7981 ccgcggccct tcgggcatcc cttcttctgg taggccgccg cgcttggcag cgggcgcgtg
     8041 ctgccgatag aatcctgggc ctgccgagga gcgctgcgac cccctgatcg tcccggggcc
     8101 aggctcggca accgatcaac ggcgctcaca aaccttcagc cggtttgtgg cgccgttcgc
     8161 ttttgtgcgt ggcgttgccc ggcgaccgtc gaacgaccga ggaacacgcc atgcaagccg
     8221 accgcacgac cgaactccgc cagcttctcg ccgagcgcat cctgatcctg gacggcgcga
     8281 tgggcaccat gatccagcag gagaagctgg gcgaggcgga ctaccgcggc gagcgcttcc
     8341 tcgatcaccc caaggacctc aagggcaaca acgacctgct ggtgctgacg cgcccgcagg
     8401 tcatcgccgg catccaccgc gcctatctcg aggccggcgc ggacatcatc gagaccaaca
     8461 ccttcaacgc cacccgggta tcgcaggccg agtacgggct ggaggcgctg gcctacgagc
     8521 tcaacgtcga aggcgcgcgc ctggtgcgcc ggctgtgcga cgaatacacc gcgcgcaatc
     8581 ccgccaggcc gcgctactgc gccggcgtgc tcgggccgac ctcgcgcacc ctgtcgatct
     8641 cgccggacgt gaacgacccc ggctaccgca acgtcagctt cgatgcgctg gtcgacgact
     8701 actacgactc ggccaagggc ctgctcgaag gcggcgccga cctgctgctg atcgagacca
     8761 tcttcgacac cctcaacgcc aaggcggcgg tgttcgcgat cgagaggctg ttcgaggacc
     8821 tcggccgccg ctggccggtg atgatctccg gaaccatcac cgacgcttcc ggccgcacgc
     8881 tgtcgggcca gaccgccgag gccttctgga actcgctcag ccacgcgcag ccgatcagct
     8941 tcggcctcaa ctgcgcgctc ggcgccgacc agctgcgcca gtacgtcgag gagctgtcca
     9001 gcgtctgtga cacgcacgtc tccgcccatc ccaacgccgg cctgcccaac ccgctgtcgc
     9061 ccaccggcta cgacgagacg cccgagcatc tcgccggcga gatccgcgag tgggcgcaga
     9121 gcggcctggt gaacatcgtc ggcggctgct gcggcaccac cccggcgcac atcgcggcga
     9181 tcgcgcaggc cgtggcgggg ctcgctccgc gtgcggtgcc ggtgctggag aagaagcttc
     9241 gcctgtcggg cctggagcct ttcaacgtcg gcggcgacag cctgttcgtc aacgtcggcg
     9301 agcgcaccaa cgtcaccggc tccaaggcct tcgcgcgcat gatcctcgag ggccgcttcg
     9361 acgacgcgct cgcggtcgcg cgccagcagg tggagaacgg cgcccaggtc atcgacatca
     9421 acatggacga ggcgatgctc gactcggtcg ccgccatgga gcgcttctgc aagctgatcg
     9481 cctccgagcc cgacatctcg cgcgtgccga tcatgctcga ctcgtcgaaa tggtcggtga
     9541 tcgagaccgg cctcaagtgc atccagggca agggggtggt gaactcgatc tcgatgaagg
     9601 agggcgaggc cgagttcctg cgccaggccc ggctcgcgcg ccgctacggt gccgcggtga
     9661 tcgtgatggc cttcgacgaa cagggccagg ccgacacctt ccgccgcaag accgagatct
     9721 gcgcgcgcgc ctacacgctg ctgaccaagc ccgtggccga gggcggcgcc ggcttcccgg
     9781 ccgaggacat catcttcgac cccaacatct tcgccatcgc caccggcatc gaggagcacg
     9841 acaactacgc ggtcgacttc atcaacgcgg tggcgtggat caaggagaac ctcccgtacg
     9901 ccaagacctc gggcggggtg tcgaacgtgt ccttcagctt ccgcggcaac gacccggtgc
     9961 gcgaggccat ccacaccgtc ttcctgtacc acgcgatcaa ggccggcctg tcgatgggca
    10021 tcgtcaacgc cggccagctc ggcgtgtatg acgagctcgt ccccgagctg cgcgacaagg
    10081 tcgaggacgt ggtgatgaac cgtcgcccgg gtgccggcga ggcgctggtc gagttcgcgc
    10141 agacggtgaa gggccaggcc aaggaatccg cgcaggacct cgcctggcgc gagtggccgg
    10201 tggaggagcg cctgtcccac gccctggtca agggcatcac cgagttcgtc gtcgccgaca
    10261 ccgaggaggt tcgggcgaag ctggaagccg aaggcaggcc gccgctggcg gtcatcgaag
    10321 gcccgctgat ggcgggcatg aacgtggtcg gcgacctctt cggcgcgggc aagatgttcc
    10381 tgccccaggt ggtgaagtcg gcgcgcgtga tgaagcaggc ggtggcccac ctcattccct
    10441 acatcgaggc cgagaagctg cgcaccggcg ccagcagcaa gggccgcatc gtcatcgcca
    10501 cggtcaaggg cgacgtgcac gacatcggca agaacatcgt cggcgtggtg ctgggctgca
    10561 acggctacga ggtgatcgac ctcggcgtca tggtgccggc ggcgaagatc ctcgaagcgg
    10621 cgaaggagca cggcgcgcag gcgatcggcc tgtccggcct gatcacgcct tcgctggagg
    10681 agatgagcca cgtcgccgcc gagatgaagc gccagggctt ctccgtgccc ctgctgatcg
    10741 gtggcgccac caccagccgc aaccacaccg cgatcaagat cgccccgcac tacgaccagc
    10801 cggtggtgta cgtcccggac gcctcgcgtg cggtgggcgt ggtcactgcg ctgctgtccg
    10861 aaggccagag cgaggccttc aaggccgagg tcgccgccga ctacgagaag atccgtgccc
    10921 tgcatgcgaa caagaagggc gtgcagctgg tgagcctgga ggccgcgcgc gccaatggct
    10981 tccgcacgga ctggacggcc gagcgcgtgg ctgcgtgcag caccgcccac caggcgggct
    11041 acgcgcccta ccagccgccg cggccgaaca tgctcggcgt gcaggcgatc gacgtcgagc
    11101 tcggcgagct ggtgaactac atcgactggg gccccttctt ccagacctgg gacctcgccg
    11161 gccgcttccc cgccatcctc gatgacgaag tcgtgggcga gaccgcgcgc aacgtcttcg
    11221 ccgacggcaa ggcgatgctc gacaggatcg tcgccgagga gtggctgcag gccaaggcgg
    11281 tgttcggcct gttcccggcc aatgcggtgg acgacgacat cgagctctac accggcgagg
    11341 accgcaagca cctcgccatg gtgtggcacg gcctgcgcca gcagcacgag cgcccgacgg
    11401 gcaagccgca ctggtgcctg gccgacttcg tcgcgcccag ggactcgggc gtgcccgact
    11461 gggtcggcgc cttcgcggtg accgccggcc tcggcatcga ggcgaaactc gccgagttcg
    11521 aggccgcgca cgacgactac cacgcgatca tgctcaagag cctggccgac cgcctcgccg
    11581 aggcctgcgc cgagtggctg cacgagcgtg tgcgccgcga gtgctggggc tacgccgccg
    11641 acgagacgct gggcaacgag gcgctgatcc gcgaggaata ccgcggcatc cgcccggcgc
    11701 caggctatcc ggcctgcccg gaccacaccg tcaagggccc gctgttcgag ctgctcggtg
    11761 cacgcgagcg catcggcatg gagctgaccg agagctacgc gatgatgccg gcggcggcgg
    11821 tgagcggctt ctacttcgcc caccccgaga gccactactt cgccatcccg aagatcggtc
    11881 gcgaccagct cgaggactgg gcgcgccgca ccggcatgga ggtcgacgag gccgcacgct
    11941 ggctggcgcc gctgctctga gcgggcgccc gtcccgccgc ccggttcgcg cctgccggcg
    12001 ctcctacagg ggatccgcga cggttttcat gtaggggcgc cggcaggcgc gaatgcagcg
    12061 tcccagcccc tgaacgcgtc gcctccgcac cgcccgcttc gcgcctgccg gcgctcctac
    12121 gggggatccg cgacggtttt catgtaggag cgccggcagg cgcgaatgca gcgtcccagc
    12181 ccctgaacgc gtcgcctccg caccnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12301 nnnngcgccg gcaggcgcga atgcagcgtc ccagcccctg aacgcgtcgc ctccgcaccg
    12361 cccgcttcgc gcctgccggc gctcctgcgg ggagcgcgcg agggttttcg tgtaggagcg
    12421 ccggcaggcg cgaatgcggc gcttcagccg cgcagcgcgg cggcgtggtg gcgcaggtgg
    12481 tcgtcgatga agctggcgat gaagtagtag ctgtggtcgt agcccggctg caggcgcagg
    12541 ttcagcgggt ggccggcggc ggcgcaggcg gcgcgcaggg cctcggggcg gagctgttcg
    12601 gcgaggaagc cgtcggcctc gccctggtcc accagcagcg gcaggcgctc gcgggtgccg
    12661 gcgatcagcg cgcaggcgtc ccactccagc cagcgcgcgc gatccgcgcc gaggtagcgc
    12721 gcgaaggcct tctcgcccca ggggcaggcg ctcgggttgg cgatcggcgc gaaggccgac
    12781 accgcgcggt agcgccccgg gttcttcagc gcgcacacca gcgcgccgtg cccgcccatc
    12841 gaatgccccg agatcgcgcg cgcgtcgctc accgggaagt gcgcctccac gagcgcgggg
    12901 agctcctcca ccacgtagtc gtacatgcgg tagtggcggc gccacggctc ctcggtcgcg
    12961 ttgacgtaga agcccgcgcc cagcccgaag tcccacgcgc cgtccgggtc gcccggcacg
    13021 ccggtgccgc gcgggctggt gtcgggcgcc acgatcgcga tgccgagctc ggcggccagg
    13081 cgctgggcgc cggccttctg catgaagttc tcatcggtgc aggtgagccc ggacagccag
    13141 tacagcaccg gcaccgggcc ggcctcggcc tgcggtggca ggtagatcgc gaacaccatg
    13201 tcgcagccca gcgccgccga gcggtggcgg aagcggcggt gccagccgcc gaagctgcgg
    13261 ttggcggcga gctgctcggg ggcggtcgtc atcgcggcct ccgccatcag tacaggatca
    13321 ccgagcggat gctcttgccc tcgtgcatga ggtcgaaggc cttgttgatg tcctccagcc
    13381 ccatgcggtg ggtgatgaag gtgtcgagcg ggatctcgcc gcgctgcgcc atgtcgacgt
    13441 agccgggcag ctcgctgcgc ccgcgcacgc cgccgaaggc cgagccgcgc cacacccggc
    13501 cggtgacgag ctggaagggg cgggtggaga tctcctcgcc cgcgccggcc acgccgatga
    13561 tcaccgactc gccccagccc ttgtggcagc actccagcgc cgagcgcatc accttgacgt
    13621 tgccgatgca ctcgaaggag tagtccacgc cgccgtcggt gaggtcgacg atgacctcct
    13681 ggatcgggcg atcgtagtcg agcgggttga tgcagtcggt ggcgccgagc tggcgcgcga
    13741 tctcgaactt ctcggggttg atgtcgaccg cgacgatgcg cccggccttg ttcatgaccg
    13801 cgccgatgat cgccgacagg ccgatgccgc cgaggccgaa caccgccacg ctggcgcccg
    13861 cctcgacctt ggcggtgttg cgcaccgcgc cgatgccggt ggtgacgccg cagccgagca
    13921 ggcagacctt gtcgagcggg gcgtccttgc ggatcttcgc cacgctgatc tcgggcagca
    13981 cggtgtattc cgagaaggtc gacgtgccca tgtagtggaa gatcggcttg ccgtccttgc
    14041 tgaagcggct gctgccgtcc ggcatcaggc ccttgccctg ggtggcgcgg atcgcctggc
    14101 agaggttggt cttgcccgac aggcagaact tgcacttgcc gcattcgggt gtgtacagcg
    14161 ggatcacgtg gtcgcccacc gccaccgagc tcacgccttc gccgatcgct tcgacgatgc
    14221 cgccgccctc gtggccgagg atggccggga agatgccttc cgggtccgcg ccggagagcg
    14281 tgtaggcgtc ggtgtggcag acaccggtgg cgatgatgcg aaccagcact tcgcccgccc
    14341 tgggcggggc gacgtccact tcggtgactt cgagcggctg cttggcagcc caggcgacgg
    14401 cggcacggga gcggatcatg ggatttcctt ttcgattggg tccaaacggg tattctaggc
    14461 gaaacgcccg ccacgtccgt gacccacgct gcgtggcggc gtatcatcgt cattcgctaa
    14521 tattcactgg agccgcacat ggccaccctc gaactcaccg ccgagaactt caacgaaacc
    14581 gtggagcaga accccatcgt gttcctcgac ttctgggcgg cctggtgcgg cccctgccgc
    14641 aacttcgcgc cgacctacga ggcggcggcc gaggccaacc ccgacatcgt gttcggcaag
    14701 gtcgacaccg aggcgcagca ggacctcgcc gccgccttcc agatccgctc catccccacc
    14761 atcgcggtga tccgcgaggg cgtcatggtg ttccgcgaat ccggtgcgct gccggcgagc
    14821 gcgctgaacc aggtgatcga gggcgtgcgc gggctcgaca tggaccaggt gcgtgccgag
    14881 atcgcccagc agcaggcggg cgcgcagcag ggctgaacga cgctcgagca ggatggcggc
    14941 cgccgctcag ccaggtggtg cgggtgtcag tgcgcgcgcg gccgcgttgc ggatggcctg
    15001 catcgccgga tgtaagaggc ggcgctcggt ggtgatcgcg tacacccgcg cgcgcgcatc
    15061 gggcacctcg ccgagcaggc gcaccccgta ctgccggcac acgtagtcgg caatcgtggt
    15121 gggcgcggcg aagacgccgt cgccggcctg gccgaaggcc ttcatcaggg cgctgtcgtc
    15181 gaactcggcg acgatcgccg ggcggatgcg catgcgctcg aaccactgca gcagcgcgcc
    15241 gcggtgggcg acgtcctccc caggcagcag gaagggcgcg ccgtcgagca ggcgcggaaa
    15301 accgccctgc aggcgcgcgg ccagcgccgg cgcggcgaac acgctcagcg tgctctcgcc
    15361 gagcaggctc tcgtggccgc gcacgctgac ctcgggcggg atcgggcggt cggcgatcac
    15421 caggtcgagg cggtgcaccg cgagctcggc aagcagctcg gacagcggcg actcgcggca
    15481 caccagccga cccgggcgct ccaggcgcag cgccggctcg atcaggcgat gcaccatcga
    15541 cttgggcatc gagtccggga tgccgatgcg aaagggcagg ctgcggcgca ggctgtcgtc
    15601 gcgcagcgtc tccacgatct ggtcgccgag cgcgaagatc tcctcggcct gtcccaggat
    15661 gcgctcgccc gcctcggtga gcgccaggcg gcggccgctg cggcggaaca gggtgacgcc
    15721 gagcgcgccc tcgaaggtcg cgagctgcgc gctgatcgag tgcggcgcca gcccgagcac
    15781 ccgcccggcc tcggcgatgg tgcccacgcg tgccacggtc cagaagtagc gcaggtgctt
    15841 gtagttgagg tcgctattga ccatggctgg cggttccgtc gaaaaaatcg atcaatcgac
    15901 taatcgtagt cgactttttc ggcgaaggct tctcccgtag tctgcactcg tcggctgcgg
    15961 cgcttccccc gggagcgcgc ggcgacgcaa gagaccgcac acgaaaggag accacgccat
    16021 gcgccactac gaaacgaaca gcaccccggc ggccgcccgc ctgcttgccc tcaccgtgct
    16081 cgccgacggc ggcctggacc gcaacgaggt cgacacgatg atgcacaccg acctcgcccg
    16141 ccgcctcggc atcggcagcg tcgagttcga gcgcatcctg cgcgaatact gcgacgacct
    16201 gatgttgagt gcgcactacc tcgacggcgt gcgcctgaag gtggccgacg aggtgctcga
    16261 cctgctgctc gaggacatcg ccgatcccag gctgcagcag gccctgctgc gcaccatgca
    16321 ggacatcgtc agcgccgacg gcgtggagac ctcggccgag gtcgaggtgc tggcccgcgc
    16381 gctggagaag tggggctcgc gcccgcacta gggcgcaacc gaaagaacga ggcggcgagc
    16441 gcggctggaa aatggtccgg ccgcttcgcc gccaccacca cggaggcagt catggaggca
    16501 atgaggcccg gcaccggcaa ggcccacgac aatcacctcg gcgatcgtgt cgacgacccg
    16561 ctgatcgatc gcctgcactg gatcatccgc caggcgatcc gcgtgctggc ggtgctgatg
    16621 gtggcggtga tcctgtggac ggtggccgac gtcgtcctcg tgctctacga gaagctgtcc
    16681 gatccgccct tcctgctgct cgacctcaac gacatcttcg tggtcttcgc cgccttcctg
    16741 gcggtgctga tcgcgatcga gatcttcgtc aacatcacgc tctacctgcg cgacgacgtc
    16801 atccacgtca agctggtgat cgccaccgcg ctgatggcga tcgcgcgcaa ggtgatcgtg
    16861 ctcgacctga cgacgctcga gccgatgtac ctgttcgcga tcggcgtgat cgtgctcgcg
    16921 ctcggcgtga cctactggct ggtgtcggcg cggccgggag actgacggcc gcgcccgcgg
    16981 ctcgcctcac tcgaacagcg cgcccacgct ctggccgctg tggatgcgct cgatcgccgc
    17041 ggcgaacagc ggcgcgacgt tgagcacggt gagcttgtcg aggcgcttgt cctcgggcag
    17101 cgccacggtg ttggtcacca ccaccgagtc gatcgccgcc gcgcgcaggc gctcgatcgc
    17161 cggcccgcac agcacgccgt gggtggcggc ggcgtggatg ctgcgcgcgc cggcagcctt
    17221 cagggtgtcg accgacgaca ccagggtgcc ggcggtggcg atctcgtcct cgaagatcac
    17281 cacgtcgcgc ccggcgacct cgccgaccac ggcgccctgc ttgaccgcgg tgtccgagac
    17341 gcggcgcttg tcgatgatcg ccatcgggat gccgagcttc tccgagaagc gcccggtgcg
    17401 cttggcgccg cccgcgtcgg tggccactgc gaccatgttc gacaggtcgt ggcggttgcg
    17461 gaagtggtcg gcgatcagcg acaccgcggt gaggtggtcg accggcacgc tgaagaagcc
    17521 atgcacctgg tcggcgtgca ggtccatggt cagcacgcgg ttcgccccgg cggtctgcag
    17581 caggtcggcg atcaggcggc cggtgatcga gatgcgcggc gcgtccttct tgtccgagcg
    17641 cgcgtaggag taatagggga tcaccgcggt gatgcgctgc gccgaggcgc tgcgcagcgc
    17701 gtcgagcgtg atcatcaatt ccatgatgtg ctcgctcacc ggctcggtga aggattgcac
    17761 gacgaagacg tcgcgctcgc gcacgttctc ctggatctgc acgcgcaggt tgtcgttgga
    17821 gaagcgcgcg atgtcgatcc tgcccgggcg catgccgagg cggttgctga tgtcgcacgc
    17881 gagctcgcgg ctggcgttgc aggcgaagat ctgcaggccg tgcttgatca tcggtggagg
    17941 ctcctgtggt gggttcgcgc ggcgccgcat cggaggcgcg ggttgcggtt ccgggcgcag
    18001 gcgccatgct acgggaagag actggccgcg ggcgaatcag gaagctgaat gcctcccgaa
    18061 gcggggcttc gggagaagcc gggaggcgcc gccgcggggg gcttgcggag cgccgtcttt
    18121 tgccacatcg tggcgcaaaa cacggcggtc ggggacagca cccacgaacc cgtccgagcc
    18181 gcccggacga gactcgaatc gaggcgctca tgaatgcgct ggcttcggcg ctcggccgtt
    18241 tgcgcgggga cttcttcggc ggactcaccg ccggcatcgt ggcgctgccg ctcgcgctcg
    18301 ccttcggcgt cgccagcggc gcgggcgcgg cggccgggct ctacggcgcg atcgtgctcg
    18361 gcttcgtcgc cgcgctgctc ggcggcaccc gcatgcagat ctccggtccc accgggccga
    18421 tgacggtggt gttcgcctcc gcgctcgtgg cggtgggtgg cgacctcgcc gtggcgatgg
    18481 cggcggtgct ggtgggcggg ttggtgcaga tcggcctcgg cgtgctgcgc gctggcgggt
    18541 tggtgcgctt catcccctat ccggtggtct ccggcttcat gagcggcatc ggcgtgatca
    18601 tcgtgctgct gcagagcgcg ccgctgctcg gcgtggcgcc ggcgccctcg ccgcagggcg
    18661 cggtgctggc gctgcccggg gtgctggcga acgtgaatgg cgaggccctg ctgctcggcg
    18721 ggctcacgct gctgatcgtg ttccgcaccc cgatggcggt gagccggatc gtgcccgcgc
    18781 ccctggtcgc gctggtgggg atgagcgcgc tgtcggtcgc cgccggcctg caggtgccgg
    18841 tgatcggcga catccccgcc gggctgcccg agctggtgct gcccagcttc acgctcgaga
    18901 cctggaccac cgtggcgctg ctcggcatca ccctcggggt gctcggcagc atcgacagcc
    18961 tgctcacctc gctggtggcg gattcgatca cgcgcacccg ccaccattcc aaccgcgagc
    19021 tgatcggcca gggcatcggc aacctgctgt gcgccttcgt cggcggcctg ccgggtgcgg
    19081 gggcgaccat gcgcacggtg atcaacatca agtcgggcgg gcgggggcgc ggctcgggcg
    19141 tggtgcacgc gctcttcctg ctcgccctgc tgctcgggct ggggccgctc gccgagcgca
    19201 tcccgctcgc ggtgctcgcc ggcatcctga tcaaggtcgg cgtggacatc ctcgactacc
    19261 gcatgctgcg gctggtgcgc accgcgccgc gcgccgacgt gggcgtgatg gcggccgtgt
    19321 tcgcacttac cgtgctggtg gacctgatcg tcgcggtggg ggcgggcgtg atcctgtcga
    19381 tggcattgat catccaccgc cttgcccgcc agagccgcct gcgcgtgcgc ccgctacccc
    19441 atgtggagga gggcggtggc gaacctgccg gccatgaact ccccgggctg gacagcggcg
    19501 tccgcgtgat cgagatcgag ggcgccttct tcttcggttc ggcgagccag ctgctcgacc
    19561 gggtggacca ggtgatcggc acccgcgtgg tcgtcttcga ctgcagccgg gtgcccttca
    19621 tggacctgtc ggcgcagttc gcgctggagg agatgatcga gggcctgcac gcgcagtcga
    19681 tcgcggcgcg ggtggtggtg ccgccggaaa tccacgccca gctgctgcgc ctgggcgcgc
    19741 cgcagctgcc ggccgcaatc ctccgggatg atctcgacag ggcgctcgcg gaggcgcgtg
    19801 aaatggcgta agcaccgctc agaagcgctg cacaccaaag aaaaggcggc ctcttcggcc
    19861 gcctctgctg gaaattgcat cggatgcgtg cgatgcgggt gctcaggctt tacgccgtcc
    19921 gcgcatgagg ccaagacccg cgaggccgag accgaggatc gccagcgtac ccggctcggg
    19981 gatggtcacc ggttcggtgg tgatcagtgc cgcgaagatc gccggcgtcg tcgcctgctc
    20041 cggcgtgacg aagccgaggc agggtgtcga agcgcctgcg gcggtgcagg ctgcggtcga
    20101 aagcggtgtc aggccggagg tctgctcgaa gaaactgatg aagtactttt ggttctgcag
    20161 cggaccacca acaccgtcga ggtcatagaa aaacgggaaa ttcagcgaat ccttgtcgat
    20221 cacgaagatg tcgccgcagc cgttactgtt cacgccggtc ccgttggctc cgccgtttgc
    20281 gcacggattc gcgttattgg tcgtctcgtc gaagttgatc aggaagctca gcgtcaccgg
    20341 agacagaccc gtcgccgacg ggctaaaagg cgtcagggtc agggtcgatg acagactcac
    20401 ctggtcgagg gtcctgccgg tgacagggtt gttggcgtgg gtcagggtca ggttcgacac
    20461 cgacgctccg ttcgtggcca cctgcttcgt ggtgttgaag tcggtgaggg tcaagctgct
    20521 ctggcctgaa ctcgtggcgg gctggcccca gacgagttgg gtgtcgctga cggtggtcgt
    20581 accgccactg ccgttggtgt cgtcccaaag gaccgtgctg gtcaggaact tggcatcgac
    20641 cttgaccgtc caggtatcga caattccgtt gattagggtc gcatgcgcag ccggagcgcc
    20701 aagtgcggca agcgcagtgg ccatcgcgca catggtggtc ttcagggatt tacgggtcgt
    20761 ggctttcatg atgcacctcc tgggatcgtg gacctctcca ccgtcgcagg aaatcacgca
    20821 taagccgtgc ctaaaattaa aaagccatca aaaacaatgc cttgtgaatc ttcaacgggc
    20881 agcctcaggg aggtagtgta aaaaaaatcg acagttatcg cgatttatcc caaattcatc
    20941 cgatttcatt catatagcat gaatcgttcg cgttcatgcc gccatcgcct ctcgtccgtc
    21001 attgcaaggg cgtcgagttc cgcaggcgca gccgccgtgt cgtccaccca ctcgcgcagc
    21061 agcggcgagc cgttgatgag gtcgatggcg aggcggtcgt gctcgtattc gtaggggaag
    21121 tcacgccaca ggggatagtc gggccacagc ctgcggatcg ccttgaaggc gagcgcctgc
    21181 acccgccacg ggcgaaacgc cgcgtgctgg tagtgcgcgg ggtcctcgac atggatctgc
    21241 acgccgttgc acagcctgcc ggtgtgcttg tggaaggtgg gctcgaacca gcactcgcgc
    21301 agcacgcagc cctgcagcca ctcgggtgcc aggccgcgca tctcggcgat cagcgcgcgc
    21361 gcgtcgagat cgggcgcgcc gaagagctcc agcggccggg tggtgccgcg gccctccgac
    21421 agcgtcgtgc cctcgagcat cacggtgccg gcgtaggcgc gcgccatcca caggttgggc
    21481 gcgttggggc tggggttgat ccagctgcgc tcgccgagcg gccagccgta gccgggggcg
    21541 gcttccggac gccagccctg catctcgatc acgcgcagct cgacgtcgag ctcgagggtg
    21601 gcgacgaacc agtgcgcgag ctcgcccatg gtcatgccgt ggcgcatcgg cagggggccg
    21661 gcgccgacga agctctccca gccggggcgc agcagcgtgc cctcgactgg gcggccggcg
    21721 gggttggggc gatcgagcac ccacaccgcc ttgccgtgtc gtgccgcctc ttccagcacg
    21781 tagcgcagcg tggtgatgaa ggtgtagatc cggcagccga ggtcctgcag gtcgaccagc
    21841 agcacgtcga acgtgtccat catcgccgcg gtcgggcggc gaacctcgcc gtacaggctg
    21901 aacaccggga tgccgagcag cgggtcggtg tagtcgggcg actccaccat attgtcctgc
    21961 ttgtcgccgc gcaggccgtg ctgggggccg aaggcggccg acagctcgag gtcgggcagg
    22021 gcggcgaggg cgtcgagcga gtgggtcagg tcgcgggtga ccgaggccgg gtgggcgagc
    22081 agggcgacgc gcctgcccgc caacgggcgg cgcagctcgg gctcctgcag caggcggtcg
    22141 aggccgaagc ggacggggtg cgccatggct tcagtccgcc ttgtgcgtcg cggtggccag
    22201 ggtcagcacg aaggtgtcgc gggcgtggaa gtcgggttgc gcggcggcgt ggcgcagcgc
    22261 ccagtattcg agggtgccgt ccttgcgctc gacgaccgcg gccaggctca cctgcaggtc
    22321 gctgccggcg ggcaccgccg gcagcagctc ggccggcacg cgcgcctcca gcaccaggcc
    22381 gtcgtcggcc tggctgaaga ggatctcggg cgcggccgcg gggacgtagt cctcgatgcg
    22441 ctcgcgccag gcgcggaaac cgtacaccgc ccactgcccg gagggcgaga agttgtactc
    22501 gcgatacccg ggctcgcccg gcgcgccgag gaagacctcg aagcaggtgt gcttccacaa
    22561 ctcgtcggcg gggccgggcg tggccggcgt cgggacggcg agctgggcga cgcggctgtc
    22621 ctcgaggcgg aactcgaaca ccgcaccgcc ttcgggcagg gcgaacatgg tggcgagcag
    22681 gcggccgacc aggccctggc cgggcgcctc ggcgtccggg ctggtggggt gggggcgcag
    22741 gcccacggtg atgatgggga cgcggggacg ttcggtgagg ggctgggtca cggtgtgggc
    22801 tggcaaggag ggaacgggta acgaggggcc ggcagcgagg gcccggctgg gaggctgacg
    22861 atgcgggccg cgcacacctg cggtgcgcat gcggccggga ggcacaatgt taacccgttc
    22921 gggcagccgc gcccacgggc gccgctggcg gaagcggcac ggcctggcgg gcgtgacgtc
    22981 ctgcgcgagg gattccccgg cttgagcgcc cgcgcccggc gtcgcacact gctgcgccat
    23041 gcgtgcccct ccgctcctcg tcatcgtcct cgcccagctc ttcggtacct cgctgtggtt
    23101 ctccgcgaat gccgcaggcg aggacctcct gcgcacctgg tcgctgcagc cggccgacat
    23161 cggtcggctg acgatcgcgg tgcagctcgg cttcatcgct ggcaccctcg gcttctcgct
    23221 cagcggcctg gccgaccgct tcgcggcgag ccgcatcttc gccgtctgcg cggtcgtcgg
    23281 ggcgctggcc aacgccggct tcgcgctgct tgcgcaaggg ctgggcgagg gcctggtgtg
    23341 gcgcttcgcg gtaggactcg cgctcgccgg ggtgtatccg ctcgggatga agctggtggt
    23401 gagctgggtg ccgcagcagg cgggcgcggc gctggcctgg ctggtcggca tgctgaccct
    23461 gggcacggcg ctgccgcacg gggtgcgctt tctcgatgcc ggctggggct ggcaggccac
    23521 gctgctggtg tcctcgctgc tcgcgctgct ggcggcggcg atgatcttca agctagggga
    23581 cggcccgcat cttgcccgtc gcgccggggc gccgcggctg cgccttggcg aggggctgta
    23641 cgcgctgcgt tcgccggcct ttcgtgcctc cgccttcggc tacttcgggc accaatggga
    23701 gctgtacgcc ttctggacgc tggtgccgct gctggtgagc gcggcgcgcg gggccgaggc
    23761 cggtttgccg tccgggccgg ccttcgcggt gatcggcatc ggtgccgtcg gctgcgtgct
    23821 cggcggctgg ctcagccgcc gcatcggcag cgcgcgggtg gccgcgctgg cgctggcggt
    23881 gtcggcgctg tgctgcgcgc tgtatccctt cgcgaccgcc tggccgccgc tggcgctggc
    23941 cggcctgatg ctgctgtggg gggcgagcgt ggtggccgat tcgccgcact tctccgcgct
    24001 gtccgcgcgc gcctgcccgc ccgagagcgt gggcagcgcg ctcgccttcc agaacgcgat
    24061 cggcttcgcg atcaccatgg tgtcgatcga gctcgtcacc cggctgtggc cctcgatcgg
    24121 cgaccgcgtc gcgtggctgc tgctgccggg gccggtgctg ggcctgctgg cgctgcgccc
    24181 gttgtggtcg cgcagccgct ccggagcggg ttgagcgcgg cgggcctcgc gcgagggcgc
    24241 ttgcccgcgc gcagggagcc gggaacaatg cgggtgcccg cttcgggcgg ttccgggagt
    24301 cgcagctgat gatgaaaccc tgcaaacgtg cgttcgtcgc cctcgccctg ctcgtgctcg
    24361 ccctgcctgc ctggacgcag gctgtggtgg aggatgcgcc catgctccgg ctcgactgcg
    24421 gcggcatcgg gctcgaggag tcggagcgca tgcgggccga ggtcggcatg cacgcactga
    24481 ccgtgttttt ctcgaccacc gggggcggct gggtcaccga cgtcgagacg caggtcgacg
    24541 agccgctctc gggccagcgc gtcgaggcgt cctgcgggcc gatcggccag gtcgacgtgc
    24601 ccacgccggg gcgctaccgc atctccgcgt cctacgccgg cgagcgccag gagcactggg
    24661 tcgatctcgt gccacagggc ggcgcccgcc tgtcgctgcg ctggcaggag tgagcgcgat
    24721 cgccccggcg agcccgctcg cgcgacgcat ccgccttatc cgcacgcgtc gaagccgtta
    24781 aactcgcgct ccctgaccta ttcgagccgg agcgatccat gtctgtccag cgcgtcctca
    24841 ccgggatcac cacctcgggc acgccccacc tcggcaacta cgccggcgcc atccgcccgg
    24901 cggtcgccgc cagccgccag cccggcgtcg agagcttcta cttcctggcc gactaccacg
    24961 cgctcatcaa gaccaccgac ccgctgcgcg tgcagcgctc gacgctggag atcgccgcca
    25021 cctggatcgc cgccgggctg gacaccgacc gggtgtggtt ctaccgccag tccgacatcc
    25081 ccgagatccc cgagctcacc tggctgctca cctgcgtcgc cggcaagggc ctgctcaacc
    25141 gcgcccacgc ctacaaggcg gcagtcgatc gcaacaccgc cgagggcgtg gacccggacg
    25201 ccggggtcaa catgggcctg tacatgtacc cggtgctgat ggccgccgac atcctgatgt
    25261 tcaaggcgca ctcggtgccg gtcgggcgcg accagatcca gcacatcgag atggcgcgcg
    25321 acatggcggg cagcttcaac cacctctacg gcgagcattt cgtgctcccc gaggccgcga
    25381 tcgacgcctc ggtcgccacc ctgcccgggc tggacggccg caagatgagc aagagctacg
    25441 acaacaccat cccgctgttc gtgcccaccg ccgagctcaa gaagctgatc ttctccatcg
    25501 tcaccgactc gaaggccccg ggcgagccca aggacgccga cggctcggcg ctgttccagc
    25561 tctatcaggc gttttccacc gccgaggaga cgcgcgcgat gcgcaccgcc ttcgatgagg
    25621 gcatcggctg gggcgaggcc aagcaggcgc tgttcgacaa gatcgaggct gcggtggcgc
    25681 cgatgcgcga gcactacctg gcgctgatcg ccgagccggc gcgcatcgag aagcacctgc
    25741 acgagggcgc cgccaaggcg cgcgcgatcg ccaccccctt cctcgccgag ctgcgccacg
    25801 cggtgggact gcgcaacctg gccagcgtgc cgcaggcggc cagggcggcg aaggcgaagg
    25861 ccgcgctgcc gcagttcaag cagtaccgcg aggccgacgg tcgcttccac ttcaagctgg
    25921 tcgacgccga cggccgcctg ctgctgcagg gcgcgggctt cgcctcgccg cgcgaggcgg
    25981 gggctgcggt ggcggcgctc aagcagggcg ctgccttcga gatgagggac ggggtcctgt
    26041 ggctggaggg cgcgcaggtg gcgacgctgg cggaaggcgt cgacgaggcc gacctgcgcg
    26101 cggcgctcgg cacattcgcc gactgagcgc gcggggcggc cagcccggcg ccggcggttc
    26161 gccgcgctca gctgaagctg ccggcgacgt actccgccag gcactccgcc gcttccgaag
    26221 cgttctcgcg gctgcggtgc acgcagacgt cgaggagtcc catctcgggg aacccctccc
    26281 gtgcgcccag cgtgcgcacg cccgccggca ccgtgctctc cgccagcagg gtcacgccca
    26341 ggccggcgcg cacggcggcg atgatgccgc tgtagctgga gctggtgtag gcgatccgcc
    26401 agctgcgatt cagccggccc agggtctgca ggatccggtt gcggtagatg cagggcggcg
    26461 gggccagcac cagcgacagg ggttgctgct cgtgacgcgt gtggtccgcg ctggtgatcc
    26521 acaccagcgg ttcggtatgg acctgcacgc ccccgctcgc ctgaccctga tcgtgcaagg
    26581 cgatgacgag gtcgaattca cccttctgct ggcgctcgag caggttcttg ctcaggtcgc
    26641 aggtcacctc cagcgtgacg cccgggtgtg actgcgcgaa cttgccgagg atggtcggca
    26701 gcagcgaggc catgtactcg tgcggtgcgc ccaggcgcac gctgcccgcc acccgcgacc
    26761 gctgcaggct cgccaccgcc tcgtcgttga gcgccagcat gcgtcgggca tagctggcga
    26821 gcgtggcccc ttcctcggtg agtttgacgc gatgcgtgcc gcgctcgacg agctgggtgt
    26881 cgagcatttc ctcgagtcgc cgcatctgca ggctgaccgc cgattgcgtc cggcccaccg
    26941 cgtcgccggc gcgcgtgaag ctgcccagat ccacggcctt gatgaaggtg cgaagaagct
    27001 ccgtgggcag attcatcatg gcctcgcatt catttccaag attaattatt tcattggaac
    27061 tatcaacttc gcaaatgaaa ccccacggtt aagatgcatt ggcgaccgct gctggcggcc
    27121 tgcccgatca atcagactga gggagacatc atgagcatcc tgaaatttac cgaagaccac
    27181 gagtggctgc gagtcgaagg cgatgtcgcc accgtcggca tcaccgacta cgcgcagaac
    27241 gcgctcggcg acatcgtgtt cgtgcagttg cccgatgtag gcgccagctt cgcccggggc
    27301 gacgaagcgg ccgtgatcga gtcggtgaag gccgccggtg agctgaagat gccgctcgcc
    27361 ggcaccgtcg tcgaggtgaa cccggcgctg gtcgatgcgc cggcgacggt caacgaggat
    27421 ccgctcggcg caggctggtt catccgcgtc cgcctggacg acccctccgc cgccgaggcg
    27481 ctgctggacc aggccgccta cgaaaagctg accgcctgat cggcgccgtc cgctcgatcc
    27541 cgcctgcatc gcctcttcct ggaccgcccc tgccatgaac atccacgaca tccgcttccc
    27601 tgcgacgctc gcccagctcg agcagcgcga cgacttcgtc ggccgccatg tgggcccgga
    27661 cggcgccgag acgcgcgcca tgctcgacgt gctcggcctc gactcgctcg accagctgat
    27721 cgacaaggtc atccccgccg ccatcctgtc ggcggccccg ctggccctgc ccgaaggccg
    27781 cagcgaaccc gaggcgctgg cgatgctgcg cgcgatcgcg ggcaagaacc gggtgctgcg
    27841 ctcgttcatc ggcacgggct accacgacac cttcacgccc acggtcatcc tgcgcaacgt
    27901 gctcgagaac ccggcctggt acaccgccta caccccgtac cagccggaga tctcgcaggg
    27961 tcgcctggag gcgctgctga acttccagac catggtcacc gacctcaccg gcctggagat
    28021 cgccaacgcc tcgctgctcg acgaggccac cgccgcggcc gaggccatgg ccttctgcca
    28081 gcgcctgtcg aagagcaagg cgaaggcctt cttcgtctcg cgcgactgcc acccgcagac
    28141 catcgaggtg gtgcgcaccc gcgccgagcc gctcggcttc gaggtcatcg tcggcgacgc
    28201 cgcgaccgaa ctcgctgcgc acgaggtctt cggcgtgctg ctgcagtacc cggcgagcac
    28261 cggcgaggtg gtcgattacg ccgccatcgt cgccgccgcg cacgacagga aggcgctggt
    28321 ggtggtcgcc gccgacctgc tcgcgctcac cctgctcaag cccccgggcg agttcggtgc
    28381 cgacgtcgcc atcggctcga cgcagcgctt cggcatcccg atgggtttcg gcggcccgca
    28441 cgccgcctac ttcgccaccc gcgacgagca caagcgcgtg atgcccgggc gcgtggtcgg
    28501 cgtgtcgatc gacagccacg gcaagaaggc ctaccgcctg gcgatgcaga cccgcgagca
    28561 gcacatccgg cgcgagaagg ccacctccaa catctgcacc gcgcaggccc tgctcgccat
    28621 catggccagc atgtacgcct gctaccacgg cccggacggc ctgaccacga tcgcgcgccg
    28681 cgtgcatcgc ctcaccgcga ccctggccgc cggcctgcgc cgtctcggcg tcgacgtgcc
    28741 gacgacggcc ttcttcgaca cgatcaccgt gcgcgtcgcc gacgcagccg cggtgcatgc
    28801 cgccgcgcgc gccgcgggca tgaacctgcg cgagatcgac gccggcacgg tcggcatctc
    28861 cctcgacgag accacccgcc gcgcggatgt cgaggcgctg tgggcggtgt tcggcacggg
    28921 tgccgcggcg ctggatttcg ccgccgtcga agcccaggtg caggaggccc tgccggccgc
    28981 gcaactgcgc agctcggcct tcctgaccca cccggtgttc agcgcctacc ggtccgagac
    29041 ccgcatgctg cgctacctgc gcagcctggc cgacaaggac cttgcgctcg accgcacgat
    29101 gatcccgctc ggctcgtgca ccatgaagct caacgccacc accgagatga tcccggtgac
    29161 ctggcccgag ttcggcgccc tgcacccctt cgcgcccgcc gaccagaccg cgggctacgc
    29221 ccagctcacc gccgagctcg agcagatgct gtgcgcctgc accggctacg acgcggtgtc
    29281 gctgcagccc aacgccggct cgcagggcga atacgccggc ctgctggcga tccgcgccta
    29341 tcacgccagc cgcggcgagg gccatcgcga cgtgtgcctg atcccgagct ccgcgcacgg
    29401 caccaacccg gcgacggcga acatggccgg catgcgcgtg gtcgtggtgg cttgcgacac
    29461 caacggcaac gtcgacgtcg ccgacctcaa ggccaaggcc gcgcagcatg ccgagcagct
    29521 cgccgcgatc atgatcacct acccgtccac ccacggcgtg ttcgagaccg cggtgcgcga
    29581 gatcaccgac atcgtgcacg cccacggcgg ccaggtgtac atcgacggcg ccaacctcaa
    29641 cgccatggtc ggcctgtgcg gcccgggcca gttcggcggc gacgtctcgc acctgaacct
    29701 gcacaagacc ttctgcatcc cgcacggcgg cggcggcccg ggcgtcggtc cgatcggcgt
    29761 caagtcgcac ctcgcgccct tcctgccggg ccacgctgcg gtgggcctcg agggcatcgg
    29821 cgcggtggcg gccgcaccct ggggcagcgc cagcatcctg ccgatcacct ggacctacat
    29881 cacgctgatg ggccgcgatg gcctgcgcca cgccacggtg atggcgatcc tcaacgccaa
    29941 ctacatcgcc cagcgcctcg agccgcacta cccggtgctc taccgcggcg agaacggcct
    30001 ggtcgcgcac gagtgcatcc tcgacctgcg cccgctcaag gacagcaccg gggtcacggt
    30061 cgatgacgtg gccaagcgcc tgatggactt cggcttccat gcgccgacga tgtccttccc
    30121 ggtgcccggc acgctgatga tcgagccgac cgagagcgag tcgaaggccg agctcgaccg
    30181 cttctgcgac gcgatgatcg cgatccgcgc ggagatcgcc aaggtcgcca gcggcgagtt
    30241 cgacgccagg gacaacccgc tggtcaacgc cccgcacacc gccgaggcga tcgccggcga
    30301 gtggacccac ccctacagcc gcgagctcgc cgcctacccg gtggccagcc tgcgcggcaa
    30361 caagtactgg tcgccggtcg gccgcgtgga caacgtgtac ggcgaccgca acctggtgtg
    30421 cgcctgcccg ccgatgtccg actacgaaca agcctgagga gccccgcaca tgaacgtctc
    30481 tttcatcgtc accctggtgg gcgaggatcg cccgggcctg gtcagcgcgc tcgccgagcg
    30541 cgcggccgcg aacggcgcca actggctcga cagcagcatg gcgcatctgg ccggcaagtt
    30601 cgccggcatc gtgcgcctcg acgtggccga agcggacgcc gaccgcctcg aggcggcgct
    30661 gcgcgcgctg tcctcgaccg gactgagcct gagcatcgag cgcggcaccg ccgcggcggg
    30721 cacggcgggc ggcgagctga tccgcatgga gctgctcgcc cacgaccgcc ccggcatcgt
    30781 gcgcgacatc tcctcggtgc tggcgcggca cggggcgagc atcgagcgca tggacagcgc
    30841 ctgcgagagc gcgtccttca gcggcgaggc gatgttccgc gccgagctcg aggtccgcgt
    30901 gccggcgagc gtctcggccg gcgaagtgca ggcggcgctc gagtcgctgg ccaacgagct
    30961 gatggtggac ctcaagctgg agaccggcgc ctgacctgaa ccgatacgcc ggcctgctcc
    31021 ggcctgatgc agcccttccc ggggtgccga ccccctccat tcggtcacta caagcggaga
    31081 atcaccatgt tcgacaagca gatgcagatc gccggctatg acgatgccct gtggcaggcc
    31141 atcgaggccg agcgcgcacg ccaggaagac cacatcgagc tcatcgcctc cgagaactac
    31201 gccagcccgc gcgtgatgca ggcgcagggc acggtgctga ccaacaagta cgccgagggc
    31261 tatcccggca agcgctacta cggcggctgc gagcatgtcg acgtggtcga gcagctcgcc
    31321 atcgaccgtg ccaagcaact cttcggtgcc gactgggcca acgtgcagcc gcactcgggc
    31381 tcgcaggcca acgccgcggt gtatctcgcg ctgctgcagc cgcacgacac catcctgggc
    31441 atgagcctcg cccacggcgg ccacctgacc cacggcgcca aggtcaactt ctccggcaag
    31501 atcttcaacg cggtgcagta cggcgtcacc gacgacggcg tgatcgacta cgacgcgctc
    31561 gaggcccagg cgctcgagtg caagccgaag atgatcgtcg ccggcttctc ggcctatgcc
    31621 cgccacctcg acttcccccg cttccgtgcg atcgcggaca aggtcggtgc gctgctcttc
    31681 gtcgacatgg cccacgtcgc cgggctggtc gccgccggcc tctaccccaa cccggtgccc
    31741 ttcgccgaca tcgtcaccag caccacccac aagacgctgc gcggcccgcg cggcggcatc
    31801 atcgtcggcc gcgccaaccc cgacatcgag aagaagatcg cctcgatggt cttccccggc
    31861 acccagggcg ggccgctgat gcacgtgatc gccgccaagg cggtggcctt caaggaggcg
    31921 ctcgagcctt cgttcaagga ataccagcag caggtgatcg ccaacgcgcg cgcgatggcg
    31981 ggcgtgttcg tcgagcgcgg ctacaagatc gtctccggcg gcaccgacga ccacctgttc
    32041 ctggtcgacc tgatcgccaa gggcatcacc ggcaaggctg ccgacgctgc gctgggcgcg
    32101 gcgcacatca cggtgaacaa gaacaccgtc cccaacgacc cgcagtcgcc cttcgtcacc
    32161 agcggcgtgc gcatcggcac gcccgcagcc accacgcgcg gcttcggcgt cgccgaggtc
    32221 accgcgctcg cgggctggat ctgcgacatc ctcgacgaca tcgacaaccc ggcggtcatc
    32281 gatgcggtgc gcgcgaaggt gtcggcgctg tgcgcccgct tcccggtgta cgggcgctga
    32341 gcgcagcgat ctcagcgtgc acgcgattga cagccgactc aacttcgcaa ctgcccaaag
    32401 gacacatgat gagcgaccac gacgctaccg cgcagatgct gcgcaccccg ctgtacgacc
    32461 tgcacgtctc cctcggcgcc aggatggtgc ccttcgccgg ctatgagatg ccggtgcagt
    32521 accctgccgg aatcctcaag gagcacatcc atacccgcag ccaggccggc ctgttcgacg
    32581 tttcgcacat gggccaggtg atgctcgtgg gcgccgatgc ggccgccgcg ctggagaccc
    32641 tggtgccggt cgacatcgtc gacctgccgg cgggcatgca gcgctacgcg ctcttcctca
    32701 acgaccaggg cggcgtgatg gacgacctga tggtcgccaa cttcggcgac ggtcgcctgt
    32761 tcgtcgtcgt caatgccgcc tgcaaggcgc aggacatcgc gcacatgcag cagcacctgt
    32821 ccgcccgctg caaggtcgag gtgctggccg accgcgcgct gctcgcgctg caggggccgg
    32881 cggcgggggc ggtgatggcg cgcctcgcgc ccgcgaccgc gaacatggtg ttcatgaaca
    32941 ccgccaccgt caccctggtc ggcgccgagt gctacatcag ccgctcgggc tacaccggcg
    33001 aggacggctt cgagatctcg gtgcccgccg acaaggccga ggcgctggcc aaggagctgc
    33061 tgagccaccc cgaggtcgct cccatcggcc tgggcgcgcg cgactcgctg cgcctggagg
    33121 ccggcctgtg cctgtacggc cacgacctcg accagaacac ctcgccggtc gagagcagcc
    33181 tgctgtgggc gctgtccaag gtgcgccgcg ccgacggtgc gcgcccgggc ggctaccccg
    33241 gcgccgcggt ggtgttcgag cacatcgcca agggcgtggc gcgcaagcgc gtgggcctgc
    33301 gcccgaccgc gcgcgtgccg gtgcgcgaag gcgccgaact ggtggacgcc gatggccgca
    33361 aggtcggcgt ggtgaccagc ggcggctttg gaccgacgct ggaggcgccg gtggcgatgg
    33421 gctacgtgga gaccgcgctc gccaagccgg gcacgcagct cgccgcgatg gtgcgcggca
    33481 agccggtgcc ggtggaggtc gcgagcacgc ccttcgtgcc gcagcgctat taccgcggct
    33541 gagggcgcgc gggccggcgc gcgctccaag cggcaaaccc gctttggcat cggccgccgg
    33601 cttcgctacc atctcgcgtt tgcgcgtccg ccccgctgca ggggcggggc atagcgttca
    33661 ccgcattcgt cgaggagtcc cacccatgat cgtcttcgtc accggcgcct ccgccggctt
    33721 cggcgccgcc atcgcgcgca gcttcgtcaa gggcggccac cgcgtggtcg ccaccgcccg
    33781 tcgcaaggac cgcctggatg cgctcgccgc cgagctcggc gacgcgctgt tgccgatcga
    33841 gctcgacgtg cgcgacgccg acgcggtggc cgcggtgccg ggtgcgctgc ccgccggctt
    33901 cgccgaggtg gatgtgctgg tcaataacgc cggcctcgcg ctcggcctcg agccggcgca
    33961 ccaggcctcg ctggacgact ggcacaccat gatcgacacc aactgcaccg ggctggtgca
    34021 ggtcacccgt gccttcctgc ccggcatggt ggcgcgcaac cgcggccaca tcttcaacct
    34081 cggctcggtg gccgggcgct ggccctacgc cggcggcaac gtgtacggcg ccaccaaggc
    34141 cttcgtgcgc cagttcagcc tcaacctgcg cgccgacctg ctcggcaccg cgctgcgcgt
    34201 gaccgacatc gagcccggcc tgtgcggcgg caccgagttc tccaacgtgc gcttccatgg
    34261 cgacgacgac aaggcggcca gggtctatgc cgacgtgcag ccgctgaccg ccgaggacat
    34321 cgccgactcg gtgtactgga tcgccacccg gccggcgcat gtgaacatca acaccatcga
    34381 gctgatgccg gtggcgcaat ccttcgccgg tctgtcggtg caccgcggct gagcggcggc
    34441 cggcgcgcca ccacatcccg aacggagcgg gcagggcacc gtctcctggc ccgcgctgtg
    34501 gcgccacgtc ggctgcggtt gcgacgcatg cctgcatgcg cttgacccct gggcgatgcg
    34561 ggcggcctgc ggaagacttc aagcctgtgg cggggttgta acagtgtcat tttcttgctg
    34621 caggatgcgc ataatttccg caatgcaaca tcgatccgcc cgtccgtgac ccccgatctt
    34681 ccgccttccg ctccggaggc tctgccggcg ccgcccgggc gccgcctgca tccccggcaa
    34741 gtactgggcg ccgccgtgtt cgtggcgctg ctggtggcga gcgtggctgg cggcctgctg
    34801 ctgtggcacg agtccgccac ctcgcgcctg caggcgcgcg agctcgcgcg ctacgccgcg
    34861 cgcctcgact acgcgctggt ggcggggccg agcgaggcga tccgctttcc cgcccacggc
    34921 cccttcgacc gccgcctcgg ctacaccgag ctggcgcgct ttgccgagcg cctgcaggcg
    34981 cgcggcttcg cgctcgtcga gcaggtgcgc ttcgacgatg cgctgctcgc ccacgtcgag
    35041 cgcggcctct tcccgcccta cgccgagaag acgcgcgccg gcctggacgt cttcgactgc
    35101 cgcggcgagc cgctgtacgg cttccgctat ccctggcgcg gctacgcgcg cttcgaggac
    35161 gtgccggcga tcgttgccca ggccctgctc ttcatcgaga accgcgagct gctcgacgag
    35221 tcgcggccga cgctcaaccc ggcggtggac tgggtgcgct tcgcgcgcgc ggcgctcggc
    35281 cagctcggac gcatggtcga tgccgacctc gacgcccccg gcggcagcac gctcgccacc
    35341 cagatcgaga agtaccgcca ctcgcccgcc ggcatcaccc tggacgcgcg cgagaagctg
    35401 cgccagatgg tgtcggcctc ggtgcgcgcc taccgcgacg gcgagcacac cctgcccgtc
    35461 cgccgccggc tggtgctgga ctacctgaac accgtgccgc tgtcggccgc gcccgggcat
    35521 ggcgaggtca atggcctggg cgacgggctg tgggtgtggt tcggggccga tttcgagcgc
    35581 gtgaacgcct tgctggcggc gccggagggc gagggggatg cgcgcatcgc ccagggccag
    35641 gccttgcgtc aggtggtggc gctgatgatc gcgcaccgcc gcccctcgtg gtatctcgcc
    35701 ggcgggcgcg aggagctcgc gcgcaccacc gacgcctacc tgcgcctgtt cgccgaggcc
    35761 ggcctgatcg gcgccgggct acgcgacgct gcgctcgccc gcccgctcgc cttccgcgac
    35821 ctcgtcgccg atccggcctg ggttccggcg acgcccggca agggcacgac cgcggtgcgc
    35881 acccggctcg ccggcctgct cgacacctcg ctgtacggcc tcgaccgcct cgacgccgag
    35941 ctcggcacca cgctgcacgg cggcctgcag caggcggtgg gcgactacct cgggcgcctc
    36001 gccgacccgg ccttcgcgcg cagccagggg ctgatcggcg agcgcatgct cgatccggcg
    36061 acgctcggcg cggtgcgcta cagcttcact ctggtcgagc gcaccgcggg cggcaaccgc
    36121 gtgcgcatac agaccgacac caccgaccag ccgctcgaca tcaacgaggg cagcaagctc
    36181 gagctcggct ccaccgccaa gctgcgcgtg ctggccacct acctcgagct ggtcgccgag
    36241 ctccacgccc ggctcgccgt gctcgaccct ccggcgctgc gccgcgtcga ggtggacgga
    36301 caggaccgcc tgacgcgctg ggcgatcgat catctcgcca gcacgcccga ccgcagcctg
    36361 ccggcgatgc tggaggccgc cctggagcgc cgcttctcgg cgagtccggg cgagggcttc
    36421 ttcaccggtg gcgggcgcca cagcttcggc aacttcaacg ccggcgacaa cgcccgcgag
    36481 cccacgctgc gcgaggcgct gcaggcctcg atcaacctgc ccttcgtgcg cctgatgcgc
    36541 gagctcgtgc gccacaccat gtaccaggtg ccgggcagta ccgcgcgcct gctcgaggac
    36601 aacgacgacc cgcgccgcgt cgactacctc gtccgcttcg cggaccgcga gggccagctc
    36661 ttcctgcgcc gtttctggcg caagtaccag gacagcacgc ccgaggagat gcgctcgacc
    36721 ctgctcgacg gcctgcgccc gggcgccgat cgcctcgccg cggtgttccg ctacctcgag
    36781 cccgaagcgc cgccgcaggc gctcgccgac ttcctcgccc gccgcctcgg cgagccgccc
    36841 gccgccgcgc gcctcgccca gctctacgcg cgcaacgcac cggaggcctt cgacctgccc
    36901 gaccgcggct atgtcgcgcg cgtgcatccg ctcgagctgt ggctggtcgc cttccgcctg
    36961 cagcatcccg aggccacgct ggccgaggcg gtggcgacga gcgccgagga gcgccagcag
    37021 gtatatcgct ggctgttccg cacccgcgcc aagggggcgc aggactcgcg catcttcacc
    37081 ttgctcgagg tcgaggcctt cctcgagatc caccgccgct gggcgcgcct gggctatccc
    37141 ttcggtcacc tcgtgccctc gctcgccacc gcgctcggca gctcgggcga tcgcccggcg
    37201 gcgctcgccg agctgatggg catcatcgtc aatgacggcc tgcgcctgcc cgtgcagcgc
    37261 atcgacacgg tgcgcttcgc gcgcgccacg ccctacgaga cggcgtttgc gatccgtccg
    37321 gtggaaggcg acgcggtgat ggcgcccgag gtcgcacgcg cgctgcgcgg ggccttgtcc
    37381 gacgtggtcg agggcggcac cgcgcgccgg ctggcgggtg ccttcaagct cgccgacggc
    37441 agcgagctgg cgctcggcgg caagaccggc accggcgaca accgcatcgt cgtgcgcggg
    37501 cgcgccggcc tcgcgctcaa ccgcaccgcc accttcgtgt tctacctcgg cccgcgccac
    37561 ttcggcacgc tcaccgccta cgtgatcggc cccgaggcgg cgagctaccg cttcacctcc
    37621 gggctgccgg tgcagatcct caagtcgatg gggcccttgc tgatcccgca cctggagccg
    37681 gcacgcgcgg acgcctgccg gccgccgccg ctgtccgggg gacccgagtc tgcgccgcag
    37741 ccgacgcctg ccgagtaggc ggcaggctgc acccccggct tacgggtgga agggccagaa
    37801 cagcgggatc agcacgctgc acagcagcca ggtgaggacg ttcatcggca cgccgaggcg
    37861 ggcgaagtcg gcgaatcggt agttgccggc gctgtagacc agggtgttgg tctggtaacc
    37921 gatcggggtg gcgaaactgc agctggcggc gaacatgacg ccgaccacga aggggcgcgg
    37981 atccaccccc atctgctgcg ccaggccgat cgccaccggg gtgaacagca ccgcgatcgc
    38041 gttgttgctc agcgcctcgg tggccacgga ggtgatcagg atcaccagcg acagcatcag
    38101 ccatggcgac atgccctcgc cgagcgcggc gagctggccg gcgagtagct ggtcgaggcc
    38161 ggagttgcgc atcgcgatgc tgatcgccag catgccgaag atcagcacca ggatcggcca
    38221 ctcgatcgac ttgtaggcct cgtcgctggt gaggcagccg gtggcgatca cgatcgccgc
    38281 gccgatcagc gccaggccct cgatcggcat cacgttgagc gcggcgagca gcatcacgcc
    38341 gacgatggtg gcgagcgcga ccggcgcctt gtggcggcgg ctggtcatct gccggccctc
    38401 ggtgatcgcg aacagatcgc cgttgtcgca gaagcgctgg aactgcgccg gcgtgccctc
    38461 caccagcagc acgtcgccgc cgagcagctg gaagtcctcg ccgatctgcg cgaacgaggc
    38521 gtcgcgccgg tgcaccgcga ccaggtggat gccatagcgc gcgagcaggt cgaggtcgcg
    38581 gatcgggcgc aggatgtagc gcgaggtctg gccgacgatc gcctccacca tcaccaggtc
    38641 gcgccggcgc agggtctcga cgtcgtgggt cgcggtgccc gccggcgcct gcaggccgac
    38701 gccgtcgctg ctgcgcagcg ccatcatggc gtcgctgcgg ctgtgcacga ccacgcggtc
    38761 gccgacctcg agccgggtgt cgggcgcggg gtcggcgagc tcggtgtcgc cgcgcaccag
    38821 gttcagcacc tggatgatgc cgttggacag gcgcgcctcg cgcagcgtcc ggccggccag
    38881 atgcgagccc tcgggcacga agagctcggt catgaaccag cgctcgccgg cgccgaactg
    38941 ctggctcagg gtctcgcgca ccggcagcag gcggggggcg aacaccagca tgaaggcgct
    39001 ccccaccagc gccatcagga tcgccggcag gctgatctcg aacatcgaga agggcgccag
    39061 gccctgctcg cgcgcgacgc catcgaccag gatgttggtc gaggtgccga ccatggtgat
    39121 caggccgccg aggatggtgg cgtaggagag cgggatcagc aggcgcgagg gcgccaggcc
    39181 ctggcgggcg gccaccgcga tcaccgccgg gatcatcacc atcaccaccg gagtgttgtt
    39241 gatgaagggc gacaccagca ggcaggcggc gatcagcgcc agcagcaacc tgcgctcgcc
    39301 cgcgccggcc gcggcggcga gccactcgcc gagctggtcc acgcagccgg tgcgcgacag
    39361 cgcgccgctg atgatgaaca ggcaggcgat ggtgatcggt gcgctgttcc cgaacacgcc
    39421 gagcacttcc ttgctgttca gcatgcccgc ggcgagcagc acgcccaccg ccaccatgac
    39481 cgcgacgtcg ggcttcgccc attcgcgcac gaaggcgagg aagaggacga cgaggacgag
    39541 gccgacgaag aggggggcgt ggagctcggg gagcagcatg gaggcggggc aggggcgcag
    39601 tgtggatggc gctgcagctt atcgccgcct ttatgcttca caaagatcga atggcgcaga
    39661 gtttattcct gccggttcat tggcaccgcg cccgcatgag ggctgcgccc tcgcgggtcc
    39721 tcaacgccgc gcagcgtcca ggcgctcctg cgcgctgcgc tcgagctcgg cggcgcgttc
    39781 gcgcaggaac tcgaggaagg cgccggcgag cggggtgagg cgcttgccgg ccggatacac
    39841 cacctgccac tgggtcggca gcggggtccc gtccacgcgc agcaccgcga tgccctcgtc
    39901 gaccgcgtgg gcgagcgcgt gggccgatag cagcgacagc cccagcccgc ccgccaccgc
    39961 ctgcttcacc gcctcgttgc tgcccagctc caggcgcggg cgcagcgcga ggccgtgggt
    40021 ggcgaagaac tgctcgacgg cctggcgggt gccggaaccg ggttcgcgca atacgaactc
    40081 ctcgtcggcg agcgcctcga gcggaagctt tctcctgcat ccggcgagcg gatgctcggt
    40141 ggatgccacc acgaccagcg gattcgacag gaagggcgtg gccaccaccg gcggcgcctg
    40201 cggcggccgg ctcatgatgt agaggtcgtc gaggttgtcg gcgagccgcc ggatcactgc
    40261 gtcgcggttg agcaccacca gcgacacctc caccgccggg cgttcgcggc ggaagtcgcc
    40321 gagcaggcgc gggatgaagg tctccgcggt gctgaccacc gccagccgca gccgcccgac
    40381 cacgtcgccg cgcagctcgg ccagcgtctc gtccaggcgc tccagctcct gctcgacccg
    40441 gttcgcggtg tcgagcacca cgcgcccggc tgcggtgagg tgcagcttgc ggccgacgcg
    40501 ctcgaacagc ggcaggccga cctgctcggc gagctggcgc agctgcgccg acagcgtggg
    40561 ctgggtcagg tgcaggcgct gggcggcgcg cgaaacgctg ccctcgcgcg agaccgcgag
    40621 caggaggcgg agctggtgga aggtgaggcg catgggtggc ggacgggctg ggcgatttac
    40681 atagataaaa gtctatttta aacgcagaaa taaatgattt ttctacatgt gtgcgccgcg
    40741 gcaaaattcg caccgcactg acgcagccgc gccctccgaa ggtccgtcgc ggcgctctcc
    40801 cggttccgct cctgcgcggt ccgctcatca aggaaaacaa cacatggtcg atgccgttcc
    40861 cttcttcttc gccctcggcg cggtggcctc gctcgcccgc tccggcctgc gcctgcccgc
    40921 cgccgtgttc gagaccctgt cgatctacct gctgctggcc atcggcctca agggcggcgt
    40981 ggagatcgcg cgctccgaga gcgccacgct gtgggtcgat gcgctgctgg cgatcgggct
    41041 gggcgcggtc atcccgctgc tggtcttccc gctcttccgc ctgcgcttct cgcgccccga
    41101 cgccgcctcg ctgtcggcgc actacggctc ggtctccatc gtgaccttcg cggtgggcgc
    41161 ggcggtgctg gccgggcgcg gcatcgaggt cgagggccac ctcgccctgc tcgccgcgct
    41221 gatggaggcg ccggcgctga tcgtggccac gctgatcgcg cgctgggggg tgaagtcggc
    41281 cgacggcagc tccaccgcgg gcgcgctggt acatgaggtg ttcgccaaca agagcgtggt
    41341 gctgctcggc ggcggcatcc tgatcggctg ggtcgccggg ccgcagggtc tggagccgct
    41401 gtcgccgctg ttcgtcgatc tgttcaaggg cgcgctgtgc ctgttcctgc tcgagatggg
    41461 cctgatcgcc gccgaccgcc tgccggacct gaagaaggcg gggctgttcc tggtcggcag
    41521 cgcactcgcc ctgccgccgg tgctggcgct ggccggctgg ggcgtggcgc agctgatggg
    41581 cctgggcgtg ggcggcacgg tgctgatgat gacgctggcc ggcagtgcgt cctacatcgc
    41641 cgcgccgacc gcgatgcgga tcgccgtgcc cgaggccaac ccggcgctcg gggtggcggc
    41701 ggcgctcgcg gtcaccttcc ccttcaatct gctgctcggg atcccgctgt acctgtggtg
    41761 ggcgcagacg atggcggggg cctgagcagg gcgccggggt cggcgacggg cgggggcggg
    41821 agcgtggctt ccgccgcggt ctgcgactcc gcgccgccgc aggcgggggc gtcctcctcg
    41881 ccctcgcggt ctgcggtctg cgcttccggc gccgcggcag tgtcctcgag cggcgccagc
    41941 actgccggtg cttcaacgtc ttcaaccacg tcggctgcag ggggcggcac atccgtgtcg
    42001 gcgacgtccg tcgcctccac cccagccccc tccgccgctt cggcgtccgc ctcggctccc
    42061 tcgggcgaca ccatctccag caccgtgtgc gaggtgcgca tcatcggggt gaactgggcg
    42121 gcctcctcga cgatctcgtc ctcgctgcgg cgcgacagca ggagtgcgaa caggcccagc
    42181 ggcacgaagg cgaggccgag gtgcagcggc agcgcgatcg tccccaccca gcccatcagc
    42241 gcgccggcga tgcccgggcc gaccgcggcc cccacgccgt gcaggaagag cacggtggtg
    42301 ttgccggcga ggatctggtc ctgcggcagg tggtcgatga ggtgcgcgac cacgatcgga
    42361 tacaccgcga aggccatgcc gccgtagagg aagagccccg ccagcgggac gtgctcgacg
    42421 tggccgaaga gcgccaccgc gaccgcggcg agcgctgcgc cgaaggccgc gacggagagc
    42481 gcgaggcggc ggtcgccggc gtcggagaag cgccccatcg gccactgcag cagcgcgccg
    42541 ccgacgatcg cggcggtcat cagcaggccg atcccggcct cgtcgaggcc gacgcgctcg
    42601 ccatacaccg gggtcaggct ccagaacgcc cccatcgaca ggccggagga cagcgcgccc
    42661 acgtaggccg cgggcgccgc gcgccaggtc atcctgaggc gcaggcgcac gcgcgtggcg
    42721 atctgcggct gtgggaagcg cgtcatcgtc accggcagca gcgacaggca gacgaacatg
    42781 gccgcgaccg cgaacagggt gaagctggcc ggcgtgtcca ggcgcagcag ctgctgggcg
    42841 ccggcgagcg cggcgaggtt cacgatcatg taggccgcga acacctggcc gcggcgttcg
    42901 ggcgcggtct ggtcgttgag ccagctctcg atcaccgcgt agaagccgac caggctcatg
    42961 ccggtcagta cgcgcagccc catccagaac cagggatgga cgacgagcgc gtgcagcagg
    43021 atgcaggccg cgacggtggc gccgaagaag gcgaaggcgc ggatatggcc catgcgccgg
    43081 atcagcttgg gggcgacgaa ggtgccgagg aagaagccga ggaagtaggt cgagccgatc
    43141 aggcccagcg tggtctcgga gaagccttcg aggttgccgc gcagcgacac cacagtgttg
    43201 agcaggccgg agccgagcag gagcagggcg atgccggcga gcagtgcgcc gatcgggacg
    43261 agggtgggca gcatgggcgg gcgccgcact gctgtccgtc ccgggtgggg gcggtcgccg
    43321 tgcggcagaa attagttttt gtgcaaacat tttagcagca ttgggttgcc ggctgccttc
    43381 ccggccaccg cctggggagg gatcaccacg ttcggcttgc caatccgcgc gcgacttgct
    43441 aaaagtccgc ccgggtgtcg gcgacacccg atccggtccg acgcggggac gaccccgccc
    43501 gccatgcgcg catcgcgcag cgaccgtcgg tttcccgcgg gacgacccgc aggacgaggc
    43561 gcgggcccga ccggcccgct gccgcccgag tttcctcccg tgtccgcaaa acccaagctt
    43621 cgtaccttcc ccgaccgcct gcgccagatc gcgatgttcg agatcggcgg cctcttgctg
    43681 gtcaccccgc ccttcgcctg ggcgagcggg gtgccgatcc gcgaatccat cggtctgctc
    43741 gcgctgctgg cgctgatggc ggcgatctgg aacggcgcct acaacaccac cttcgactgg
    43801 atcgagggcc ggctcaccgg gcgcaccgcc gaccgccgcc cgttccggct gcgcgccctg
    43861 catgcgctcg gcttcgagtc cggcctgctg ctgatgacgc tgccggtgat cgtgtggtgg
    43921 accggcatgg gctgggtcga ggcgctgatc gccgacatcg gcctggcgat cacctacacg
    43981 atctacgcct tcctgttcaa tctcggctac gaccgcctgt tcccgatcgc gcccgccgac
    44041 ggcaacgcgg cggccgcggc cgggctggcg gcggagcgct gacatgacgg ccgctggctg
    44101 cagcccgcgc gtcgacgcgg attcgcaggt cgtcgccgac gccgacctct ccgccctcaa
    44161 caccttcggc ctgcgcgcgc gcgcggcccg cctgctgcgc gtgcgttcgg tcgagacgct
    44221 gcgcgcggcg atcgccgcgc cgggctggac cgagacgccg cgcctggtgc tcggcggtgg
    44281 cagcaacctc gtgttcggtg gcgatttccc cggcacggtg ctgcgcgtgg agattcccgg
    44341 ccgccgcctg ctgcgcagtg acgcagaggc ctggatcgtc gaggccggcg ccggcgagag
    44401 ctggcacgac ttcgttcggt ggacgctggc gcagggctgg cccgggctgg agaacctgtc
    44461 gctgatcccc ggcacggtcg gcgccgcgcc gatccagaac atcggcgcct acgggctgga
    44521 gctggtcgag cgcttcgagt cgctcgacgc ggtcgagctc gacaccggcg agctgtgccg
    44581 cttcgatgcc gccgcctgcg ccttcggcta ccgtgacagc gtgttcaagc gcaatcccgg
    44641 caggtggatg gtcgtcgcgg tgcgtttccg cctgccgcgg ccgtggcgcg cgctcacgcg
    44701 ctacgccgac gtggcgcgcg agctcgaggc gcgcggtctc gcgcagcctg gtgcgctcga
    44761 ggtctcggac gcggtgatcg cgatccggcg ccgcaagctg cccgacccgg cggtgctcgg
    44821 caacgccggc agcttcttca agaacccggt ggtcgacgcc gcgcgctgcg cgcgcctgct
    44881 cgccgagcac cccgcgctgc cgcactaccc gcaggccgac ggcagcgaga agctcgccgc
    44941 cggctggctg atcgagcacg ccggctggaa ggggcgcgac ctcggcccgg tgggctgcta
    45001 cgagcgccag gccctggtgc tggtcaatcg cggcggcgct accggcgacg acgtgcgccg
    45061 catcgcgcag gccatcatcg ccgacgtcga cgcgcgcttc ggcgtgcgcc tggagcccga
    45121 gccggtcttc atctgaactg cggcgccacc gccagcaggt ggcgccgtgc agcaaatcgc
    45181 gatatcgggt gcgaggcccg caggagaacc gcatgtccca agaaccaggc cgcagtgccg
    45241 tactggacga actgcgcacc gccttcggcg ccgacgaggt cctcgccggc aacgccagcc
    45301 cgcgccacct caaggactgg agcacggcca gcggtggcac gccgctcgcc atcctgcgtc
    45361 cgcgcagcac cgcggagctc tcgcgcatgc tcgcgatctg caacacccac ggccaggccg
    45421 tggtgccgca gggcggcctc accggcctgg tcggcggcgc ggtgccgggc gagggccagg
    45481 tggtggtgtc gctcgagcgc atgaacgcga tcgaggagat cgacctcggc tcgggcaccg
    45541 tgaccgtgca ggccggcgca gtgctgcaga cactgcagga ggcctgtcac gaggccggcg
    45601 cgctgctggc gatcgacctc ggcgcgcgcg gctcgtgcca gatcggcggc aacgtgtcga
    45661 ccaacgcggg cggcaaccgc gtgatccgct acggcaacac gcgcgaatcg gtgctcggcc
    45721 tggaggccgt gctcgccgac ggcaccgtgc tgccgatgat gaaccgcatg gccaagaaca
    45781 acgccggcgt cgacctcaag cacctgttca tcggcagcga gggcgtgctc ggcatcgtca
    45841 cccgcgtcgt cctcaagctg catccgctgc cgcgcggcac cagcaccgcg ctggtggcgc
    45901 tcgccgactt cgacgccgcg ctgagcttcc tgcgccacgc gcagcagagc ctgtcggggc
    45961 aggtcagcgc cttcgagatc atgtggcgcg aatatctcga cgtcgcggtc gccaccaacc
    46021 acctgcgccg ccccttcgcc gccgactacc cggtgtatgt gctgaccgac atgcactgcg
    46081 gccagcccga gaccgacgcc cgccgcttcg agaccatgct ggagcaggcg atcgagtccg
    46141 gctgggtgct cgacgccgcg gtggcgcagt cgatggccga cgccgaggcg ctgtgggcga
    46201 tccgcgacgg catcgccgag gtgctgcgcg agcgggcgcc gacgctgaac ttcgacgtct
    46261 ccgtgccggt gggccggatc ggcgagtgtg tggcgcgcat gcgtgccaac ctggagcgcg
    46321 gctggccgca gctgcaggcg ctgttcttcg gccacgtcgg cgacggcaac gtgcacgtgg
    46381 tggtgtgcaa ggtgccgcag gacgccgaca gcctgcactc gatcgaagag gcggtgtatg
    46441 gcgtgatgcg cgactacggc ggctcggtgt cggccgagca cggcatcggc gtgctcaagc
    46501 gcgactggct ggcgtattcg cgcacgccgg cggagctcgc gctgatgcgc acgctgaaga
    46561 cggcgctgga cccgcgcggc atcctcaacc cgggcaagat gctgtagggc cgcgcgtcgc
    46621 cgcggcacta gatgatgcgg cgcggctgct cgatgatggt ctggtagacc aggctcttga
    46681 tcttcatgcg gtcttccgcg ccgagctcgt ggaagtccac cccgtagtgg tattcgatgc
    46741 cttcgccctc cgcatcgggc tcctgctgca cgttgcggat ctcggccgcg atgtccagct
    46801 cggagtgcag ctcgtggagg atcacgtcga agcgcaggcg gatgatcgag ccctgttcgc
    46861 ccagcgcggc gcgggtgtgg atcagcgcgc cggtcgcgct caggttcagc atggtgccct
    46921 cgctcggctc gccgccggtc ggcgagctca atcccaccgg gaactgggtg cgcacccgcg
    46981 tcgatttgcg gatcacgctg ccctggatga cggtcggaaa gctcaggtgc acatagtcga
    47041 agggcagctt gcacgcgcgc agcaccgagg cgcgaaatgc gaaggcgctc tggcgcgaga
    47101 acacccgcac gatcaccggg tcgttctcga ccagctccac ccgccgtccg cccgccaccg
    47161 gcgtggtcac cagcaggctg acgccgtcca tgtagccgac cacgcgcacg aaggcccgcc
    47221 acacgcccgt gctcgcggtg cattcgatct gcaggcggtc gccgacggcc agacgcatgt
    47281 cctcgaaggt gaagccgcgc tgcgcctcta cctcgtcctg tccgtccgca tgctcgtcgt
    47341 cgcgcagttc tgcgttgctc gtgtcttcgc tcatcgttcc gtccggcctc tacggggttg
    47401 cctcgatgac ggatttcagc tgctgcggac gcgccgggca aggacgaatt gcacgcccgc
    47461 acgcaggaat attcgtcgct tctgatgtgg tgccgccgca aatacggctt ctgatctccc
    47521 ctcgaccctg ctagcttgcc ggccgtgcgc atgaggccgc gccgcaacaa gccaatccct
    47581 ggacaagacc gcatgtacaa gatgacaaag ctccgaagcc ttcccgcgct cgccctcgcc
    47641 tgcgccctgg tcgccacctc cggagcgagc caggccgtga cctggagcga caccttcgtc
    47701 ggctatcgcc acggcagcga gttccacgag cccaacaatc cccgggatgt cgagaagcac
    47761 atcgtgcagt tctcccacgc cagcggctac accatgggac agaacttcct caacctggac
    47821 atcttccgct cggacgaggc ggacccgacc gtgcgcgggg gcgacaaggg cgcgaccgag
    47881 ttctatctcg tctatcggca tcaactgcac ctgggcaagg cgctcggaaa gcgcttcgcc
    47941 ttcggtccgg tgaaggagct tgcgcttacc gccggtttcg atctcaacac caaggattcg
    48001 ccggtgcagc cgcgcaagcg cgtgctcgtc gcgggtccca cgctgaagtt cgacgtgccc
    48061 ggcttcctcg atgtgagcct gctgttcggg agggagtgga accagaacaa gctcggctcg
    48121 ccgaagcagc gcatcgcgtt cgacccgcag tggatcctca acgccgcctg gggcatcccg
    48181 ttcaccgtcg gccccgtgcc gctcaagttc cagggcttcg ccaaccacct gagcaagcgc
    48241 ggtgaggact acaacggcag gaagaccaag gccgagaccc tcatgcgcgc agcgctgatg
    48301 gtcgacgtcg gccagatggt ctccggcagg aagaacacct tcctgatggg cgtgggctat
    48361 gaatactggc gcaacaagtt cggcaaccac ggcatcccgg gtgtcgaagt cgatgcgccg
    48421 accttccagg cggagtggca cttctgaggg cgtgaggagc aaggcgcacc cgtccccgtg
    48481 ccgccgccgc ggtgttgcct gcggcatttc cgcacggcgg cccgcggccg accatccgga
    48541 ttcgtgatgt gctgtatcag ctgggcggga ttcatgacgt ttcccggcct gttagttttg
    48601 cgaccgcgcg caatgccttg cgcccgagag ccaaaccaga gacaggaccg gagacaagaa
    48661 atgacaagac tcagcacccg catccagacg ctcgccgcgg ccggcgcgct gctggccatg
    48721 cctgccgcag gccaggccgc gacctggagc gacaccttcg tcggctaccg ctacggcagc
    48781 gacttccgcg agccgaccaa caccaaggac gtcgacaagc acgtcctgca gttcacccac
    48841 gccagcggct actcggtggg gcagaacttc gtgaacctgg acgtgctgca gtcggacaag
    48901 gccgacccgg ccagtggtgg cgccagcggc gcgaccgagt tctacctgac ctatcgccac
    48961 caggtccatc tcggcaaggc cttcgaccgc agcttcgcct tcgggccggt caaggaggtc
    49021 gcggtcaccg cgggcttcga tctcaacacc aagaacaccg cgttctcgcc gcgcaagcgc
    49081 ctggtggtgc tcgggcccac gctcaagttc gacgtgccgg gcttcctcga cgtcagcctg
    49141 ctcgtcggca aggagtggaa ccgttgcggt ctcgaccccg tcgcgccgtc gaccttcgat
    49201 ccctgcccca agaccgaggt gagcttcgac ccgcaatgga tcgtgagcgc ggcctggggt
    49261 atcccgttca gcgccggccc gctgccgctg aagttccagg gcttcatcaa cgtcaacggc
    49321 gagaagggca aggactacgc gggcgtgaag acccacaccg agaccctgat gcgcacctct
    49381 ctgatggtag acgtcggcca gatggcctgg ggcaggaaga acaccttcct gatgggcgtc
    49441 ggctacgagt actggcgcaa caagttcggc aaccacgcct acgccaacgg cgtcgagaag
    49501 cccggcatcg acaccaacgc gccgaccttc cagatggaat ggcatttctg acgcgtgacg
    49561 cgtgacgcgt gacgcgtgag gcgcgagtgc aggcggcgcc cgctatcccc gctccaccgc
    49621 cgcatcgcag ccgcgcaagt cacacgttca tgaccgtcac cgcgcgggtg ttcaggtagg
    49681 cgtcgagcgc ctccggcccg ccctcggtgc cgtagcccga atccttgatg ccgccgaagg
    49741 gcatctccgc gctcggcgtc gccggctggt tgatgtacag catgccgacc tcgagctcgt
    49801 gcgccaggcg gtgcgcgttc ttcagcgagc cggtgaaggc gtagcccgcc agcccgaagg
    49861 acagccggtt cgcctcggcg atggcctcgt ccagcgtggt gaagccgcgg atcgccgcca
    49921 ccggcccgaa gggctcctcg ttgaacacct tcgcatccag cggcacgccg gtcagcaccg
    49981 tgggcgcgaa gaagttgccc gcggcgccga tgcactcgcc gcccgccgcc acggtcgcgc
    50041 cgcgcgccac cgcgtcctgc acgaagtccg ccatcgccgc cacgcggcgc gaattggcca
    50101 gcgggcccat ctgcgtgccc tctgccaggc cgtcgccgac cttcagcgtg ctcgcatgcc
    50161 tggccagcgc cgcggcgaag ttctcgcgca ccgcctcatg caccaggaag cgcgtcggcg
    50221 agatgcacac ctggccggcg ttgcggaact tcgaccccgc cgacaccttg atcgccagct
    50281 ccaggtcggc gtcctcgcac acgatcaccg gcgcgtggcc gccgagctcc atggtcaccc
    50341 gcttcatgtg ctggccggcc agcgcggcga gctgcttgcc caccggggtg gagccggtga
    50401 aggtgatctt gcggatcgcc ggatgggcga tcaggtagct ggagatctcc gccggcgttc
    50461 cgtacaccag cccgatcgcg cctgccggca cgccggcatc gacgaaggcg cgcaccagct
    50521 cggcgggcgc cgcgggcgtc tcctcggcgg ccttgaccag gatggagcag ccggtggcga
    50581 gcgcggcggc ggccttgcgc acgacctggt tgatggggaa gttccacggc gtgaacgcgg
    50641 cgaccgggcc gaccgggtcc ttgatgacca tctgcgtcgc ggcgaggttg cggccgggca
    50701 cgatgcggcc atacacgcgc aggccctcgt cggcgaacca ctcgatgatg tcggccgcgg
    50761 cgagcgtctc catcttggcc tcgggcagcg gcttgccctg ttcctgggtg agcaggcggg
    50821 cgatgtcgcc ggcgcgctcg cgcatcagcg cggcggcgcg gcgcagcgtc ttggcgcgct
    50881 cgatcgccgg ggtgcggcgc caggcctgga agcccttcac ggcggcagcg acggcgaggt
    50941 cgaggtcggc gatcgcggca tgcgcgacgc ggccgatctc ctcgccggtg gcggggttgt
    51001 gcaccgccag cgtgcggccg tcgagggcgt cgcaccattg gccgtcgatc agcaggcggg
    51061 tgtcggggta ggtcatgcgg gcttcctctc gtgggaatgt ggggtccgac attctagcgg
    51121 ctggcggatg acgggcaggc gtcggtccgc cgacgtggcg tggcccggac gtgtgcaggg
    51181 aaggccagga gctcgcgacc cttcctgtag gagcgccggc aggcgcgaat gcggctgccc
    51241 tgtccgcggc taccgccgta cccggaaggg cgctcgcgac gcttcatgta ggagcgccgg
    51301 caggcgcgaa tgcnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    51361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnntgtagga
    51421 gcgccggcag gcgcgaatgc ggcgctgcgg cgggcgagcg ccgctccgcc gcggccccgc
    51481 ctcaggagat ttcccgcgcg ctcagcgtgt agctgaaggc gtcggggtcg aggctgtcga
    51541 agcgctggcc ggcaagctcg ccctgggggt acatcaggaa ggggatctcc ttgccggtgc
    51601 tgttgggcag gcgcaggtcg tgggcgtcgt tgtaggccag ccagttcatc tcccaggcgc
    51661 cgaagagctg cctgcgcacc gcggcgacct tgggatcgac catggagagc ttgcccgggg
    51721 gctcctcgag cacgaccttg cgcacgtccg ccgggtccac cggcacccag ccgaagcgct
    51781 ccaggaacac ctcggcgcgg cagtgctggg ccttggacac gttgccgctc ttgcccaggc
    51841 tcttgtagcc gaagcgggag tcggcgacgc ggatgccgta gacgtcgcgc gccggcagcc
    51901 cggccgcgcg cgcgaggccg acgaagaggg cgttgaggtc ggcgcacttg cccgagaggt
    51961 tgccggtctc cagcatgctg cggatgtcgc cgatgccgca gccgcgcacc ttgggctcgc
    52021 ggaaggtgtt gtccacgatc cagtcgtaga tcgcgcgcgc cttgtcctcg tcgcccttcg
    52081 cgccctggac gatgtcgcgt gcggtgtcgc gcacgatgcc gtcggtgggc agcagcgcgg
    52141 tggggcgcag atagagcatg cgctcggcgc gcgtcagccg ctggggttct gcgctgggct
    52201 gggtgaagtc ggtggcgcgg tcgcgggtgg cgaagcggct gaggatctcg agctggggct
    52261 gggcgacgcc cggcgcccac tcggcataga ccatctccgc gccggagcgg tcgcgcacgc
    52321 gctccatgag ctcggcattg ccctgccaga ggctgcccat cgggcgctgc caggcggtct
    52381 cgtgcatcgc cggcagcggg acccacacgc gcagcgggcc gtcgccgggc agcggctcga
    52441 tgcggctgac gagctcgaag cggcgccagc cggtctccgg cgtgggcgcg aaggcgggcg
    52501 gttcggcgag cggggtgggg gtggcgagcg gcgcggtgac cgcggccgag gccggttgcc
    52561 gggcacgcgc gagcgcaggc agcgcgaggc cggccgcgag gctgccggcg cgcaggaagt
    52621 tgcggcggtt catgagttct cccgatgagc gaagccgccc cggtgcggga tgccgccggg
    52681 gcttgatgtc tggccgttgc cggcggccgt gtgcggggcc tgcccgcggc gtggaaggcc
    52741 gatacgaagg atcggcacgc tggtccggcg cgcattgtcg gcgattgcgc gcagcgagtg
    52801 aacccgcgca ccgcgcttcc aggccccgag cgcggccctg taggagcgtc ggcaggcgcg
    52861 aacgggcggc tgtccatgcg ccggcgctcc tttcgtcgat ggattcgcgc cttgcggcgc
    52921 tcctacacgg ggtgctcgca gcgctgagac cggtttttgc aggagcgccg gcaggcgtga
    52981 gcctcggccc cctgcctgcg ccgaccttcc cgagtgcggg atctccgcca tgggcagcgc
    53041 cggcgcgggt cgatacaatg gtccgcatga atcagccgat tcccgggacg gcgtcctgct
    53101 gcccggtctg tcttggcgca tccgtgcgcc ccttcctgca cgcgggcggg cgcgactatc
    53161 tgcgctgcga agcctgcgag gcgaccttcc tgcacccggc ccaacggccg gcggcggatg
    53221 tcgagtgcgc cgaataccgc ctccaccgca acgaccccgg cgaccccggc taccgccgct
    53281 tcctcgcgcg cctggtcgat ccgctgcgcg cccgcctcgc gcccgcggcg caggggctgg
    53341 actacggctg cggcccggga ccggctctgg ccgcgatgct gcgcgaggcc ggccatccga
    53401 tgcgggtgtg ggatcccttc ttcgcccccg atcccgacgc actcgcgcgc cgctacgact
    53461 tcgtcacctg caccgaggtg gtggagcact tccacgcccc cgcggccgag ttcgcccgcc
    53521 tcgacggcct gttgcgcccg ggcggctggc tcggcatcac cacctgcctg cagaccgagg
    53581 acgcgcgctt cgccgcctgg cactaccggc gcgaccccac ccacgtggtg ttctaccgcg
    53641 cggccacctt ccgggcgatc gccgcccgct tcggctggcg ctgcgagctg ccggcaaagg
    53701 acgtggtgct gatgcacaag cccgcgccgc cggtggccgc agcgactgcc gcttcttccc
    53761 ctccccccaa ccccgaccgg gagtccccat gagctacgaa accctcctct acgacctctc
    53821 cgacggcatt gccgagatcc gtctcaaccg cccgcagcgc ctcaacgcgg tcacgcagca
    53881 gctctacgac gaactgaacg acgcgctcgg ccgcgccgag gccgcgcgcg aggcgcgcgt
    53941 ggtgctgctg accggcgagg gccgcgcctt ctgcgtcggt gccgacctca aggagcacaa
    54001 ggtcgggcgc accgccttcg accgccgcca gtacctcaag ggcgagcagg acgtgtgccg
    54061 ccgcctgatc gatctccaga agccagtggt cgccgcggtc aacggctatg cgctcggcgc
    54121 cggcgccgag atggcgctcg cctccgactt cctgctgatg gccgaaggcg cgcagctcgg
    54181 cctgccggag atctcgatcg gcaacttcct cggcggcggc gtgacctggc tgctgccgcg
    54241 cctggtgggg ctggcgaaag cgcgcgagct ggtcttcctc ggcgaacgcg tcggcggcga
    54301 ggaggcggtg cgcatcgggc tggcgaaccg ggtgttcgcg gacgcgggct tcctcgacga
    54361 ggcgcgcgcc ttcgcgcgca ggatcgcggc caaggcgccg ttctcgatgg agctcgccaa
    54421 gcgccagctc aacctctcgg ccgagcgcac gctcgacgcc tgcctcaccg ccgagctcga
    54481 gggcatgatg ttcgtcggca ccacgcgcga ctggcaggag ggcgtggatg ccttcgccga
    54541 gaagcgcgcg ccggtgttca agggggaatg acatgagcga gaacccgagc cccgtgccct
    54601 gcagcccggc gcgccgcagc ccgctgcacg acttcctcgc ccccgcctcg atcgcgatcg
    54661 tgggcgcctc ggccgatccc accaagcgcg gctacaaggc catggtcggc ctcatcaagg
    54721 gcgactaccg cgggcgcatc tacccgatca accccaaggt gcccgagatc ctcggcgtgc
    54781 cgacctgcgc cacgctcgac gacgttcccg ggccgatcga cctggcgctg atctgcaccc
    54841 cggcgaagac cctgcccggg ctgctcgagg agtgcgggcg caagggcgtc aagggcgcgg
    54901 tgatcctcgc cagcggcttc cgcgagaccg ggccggaggg cgccaggctc gagcagcagg
    54961 tgctggacgc ggcgcgtgcg ggcggcgtgc gcatcatcgg ccccaacacc tcgggcatgt
    55021 tcaacctgca ccacaaggtc aacctgctcg acctgcgcaa cgcccggccg ggcgacatcg
    55081 gcttcatctc gcagtcgggc aacatgctgc tggcgctggt gctggaggcc gagcacaacg
    55141 gccacgtggg cttctcgacc tacgtcggtc cgggcaacca gaccgacgtc ggcttcaacg
    55201 actacctgcg ctacctcggc gaggacgagc acacccgcgt ggccacgctg tacgtggagg
    55261 gcttccgcga cggccagcgc ttcctcgagg cggcgcgcga gatcaccccg gtgaagccgg
    55321 tggtggtgta caagtcgggc gccaccgagc tcggcaagaa ggccgccagc tcccacaccg
    55381 gcgcgctcgc cggcagctac gcgatgacgg tggacctgct gcgccaggtc ggcgtgagcg
    55441 tggtgcatca ctccgacgag atcctgccgg tggccgaggg cctggcgctg atgcagcagg
    55501 cgcgcggccg gcgcgtggcg gtgatcgccg acggcggcgg ccaggccacg atcacctccg
    55561 accgcctgtc ggagtccggc ctggaactcg ccgagctgtc ggaggccacg cgcaagcgcc
    55621 tggcggcgat cctgttcgcg caggcgtcgc tggcgaatcc ggtggacgtg gccggcagct
    55681 cggacgccga ccccgaggtg ctggcgcgct gcgtcgagat cgtcgccgac gacgacaacg
    55741 tcgatgcggt cttcctcgtc ggcatgttcg gcggctacca cacccgcttc gccgagtccc
    55801 tgctcggcgg cgagatgcgc gcggccgagg cgatgatcga gctcgcgcgc gccagcgcca
    55861 aaccgctggt ggtctatagc ctctacgccc cggtcaagcc gcccgcgctg cgccgcctgc
    55921 acgaggccgg gctgccggtg tatgcgtcga tcgagcaggc ggtgaaggtg ctgcaggcgc
    55981 tcgccgagcg cggcctctac ctgcaggacc gccacggcca gccgcttcag gccggcgtgg
    56041 cgcccgacga ggcgatgcag gcgatgttcg cgcgcgccca gaacgagggc cgcgacctct
    56101 acgagcacga ggcgcgggcg ctgctgcgca cgcacggcgt ggcggtcgcg gacgagctcg
    56161 tcgcccacac cgcggacgag ctcggcgcgg cgatcgagcg gttcggcgac cagccgctgg
    56221 cgatgaaggt ggtgtcgaag gacatcctgc acaagtccga cgccggcggc gtgaagctga
    56281 acctggtcgg cgaggccgcg ctgcgcgagg cctacgacca gatcatggcg agctgccgcg
    56341 cctacgaccc cggcgccgac ctgcgcggcg tgctgctgac gccgatggcg aggaaggggg
    56401 tggaggtcat cgtcggcgtg gttcgcgacc ccatcttcgg gccggtgctg atgttcggcc
    56461 tcggtggcat cttcgtcgag attctcgagg acgtcgcctt ccgtgccatc ccgctgtcgc
    56521 ggcgcgacgc cgagaccatg gtcgaccagc tcaaggcgcg caaggtcctc gccggcgtgc
    56581 gcggcgagcc cccggtggac aaggccgcgc tggtcgagct gctgctgaag gtgtcgagca
    56641 tcgtcagcgc ctatccgcag ttgtcggagt tggacctcaa cccggtgatc gcctacgccg
    56701 acgggtatgc ggtggtcgat gcacgcatca tcgccaaccg cgcggtggcc agcagctgag
    56761 gcggcgcggg catcggcacg cgaagcgcgc tccggccctg cgcaaatgca ggggccgggg
    56821 cgttgcgcgg catcggtccg cgaatgcctt gccgcgtgcc tcgagcctcg gatcggggtg
    56881 tgcaggaact ggatatcgat ggtgcagagc ctggatattg atcgggcgga ttgcgccata
    56941 acctgtcggc ctttcacgtg acagcggttg aagtgcgtct tgcccttcag cgctcgtccg
    57001 ttcgagctcc ccatccagca gcacttcctg caaagaggca cgatcttgaa ttcgaacgct
    57061 tctccaatcg aaagcccgga aatggcgcgc aagcggcgca gcaccatctt ctgggtgatc
    57121 ggcctggcct tcatcggcct ggtcttcgac ggctatgacc tcgtggtcta cggtgccgtc
    57181 ctgcccggct tcatgggccc ggatgccgcc aagtggatcg gcgaccgcgc gctgacaccg
    57241 caggaagccg ggatgctcgg ctcctatgcg atggtcggca tgatgctggg cgcgctggtc
    57301 gccggcaccc tgggcgacct gatcggccgc cgcaaggtca tgatcgcctc gatcgcctgg
    57361 ttctcgatcg gcatggcggt ttcggccatg accgaatcgg tcaccgcctt cggtatctgg
    57421 cgcttcatca ccggcctggg cgtcggcgcg ctcgccggca ccaccggcgc gatggcggcc
    57481 gagttcgccc cgcccggcaa gaagaacctc gccaccgcct tcacctacgc aggcattccg
    57541 ctcggctcgc tgctgtcggc cttgctggcg atcttcctgc tgccggtcat cggctggcgc
    57601 ggcatgttcc tgctcggcgc gctgccgctc gtcaccctgc tgccgctggc gatctggaag
    57661 cttcccgagt cggtggcctg gctggcctcg cgcggccgcc tggatgaggc gcgcagggtc
    57721 tccgagcgca cgggcgtgcc catccccgag accgagatca agccgcagca cagcgcggcg
    57781 gcccgctctt ccgacgagcg tgcgggctgg gcggggctgt tcaccgtcta tctcgtcccg
    57841 gccatcgtga tcggcttcgt gtcggcgttc tgcctgctgc tggtctattc gctcaacacc
    57901 tggctgccca agatcatgct gccgatcatg ggccagaacg gatcgctggc cttgctgctg
    57961 gtcctcaatg ccggcgccat ggtgggcacg ctgtacggct ccaccctggc ggacaagcac
    58021 agcccgcagc gcatcgtggc gctgggcttc ctggtcggtg cgctcgccat gggggccatc
    58081 ggcatgatcg cctccacgat cgatgtcccg gcggtcgcca aggcgggcga ggtccagcaa
    58141 ctcgccgacg tcggcgggat cgtcgtcgcc ctgctgctgc tcacgatcgc gatcaccggc
    58201 ctggggacct cgggcacgca gaccctgatc tacggcctcg cggccaacta ctaccgcacc
    58261 aacgtgcgcg gcgccggtgt cgcctggacg gctgccttcg gccgtatcgg cggcatcttc
    58321 gggccgatct tcggcgcctt cctggcggtg aagttcgccg gcgagctgca cagcatcttc
    58381 tatgtgctcg gtggcatcag cctcatcggc ctggcgctca ccctgatcat cccgaagagc
    58441 aaggcggcgg cggccgtgca ggcggtggcg ccgaccacgg ccccggcggc ggccgtgccg
    58501 gacggcaagt cccgtctcta cggcaccatc atggccgtgg tcgatcacac cgggaacaag
    58561 ctgacgcgcg cgcgtgtgtc cgagttcgtc tcgctcaccg gctcgaaggt ccacctggtg
    58621 tatctcgcgc cggagcacgt cctctccgcc gaggtcgacc agaccgacaa gaccatcgat
    58681 ccgcgccacg tggcgaacct gcaggagtat gtgaacgagg tgaacgccca gggcgtaccg
    58741 gccgaaggcc agatcctgac gtccaccctg ttcggtcgtg gcaaggcggt ggtcgacctg
    58801 gccgagcagc ttcgctgcga cctcatcatc ctcaacaccg aggagggcgg gcagcgtgcc
    58861 aaggccgagc ttgcccagga agtggccggg cagaacccga agatggccgt gctgatcgcg
    58921 cgctcgacgc agtaagacgc cgcagcatca cgacgaccgc cccgaccgcc ccggttcggg
    58981 gcggtttctt ttgtgcacgg gcgccgcgcc ttgctgcaag cgggcgctgg cagagcggaa
    59041 gtcgtgcgtg gaagccatcg tgccttggcc ggacagagaa gaagtttatg cactattgtg
    59101 catctaatgt gtgttcatgc cgcaattgat gcgatatagt gcactttcag gtgcctcgat
    59161 ggcaggtgcc tgcgctattg cggcgcacga gcaaggttcc tgatccccga gagagcggga
    59221 ggcggggcga gcgtcgcgaa cgtgtgcgtc cgtgcagtcc tcggtcgctc ccacaactcc
    59281 gactcaagcg ccaggaatcc atcgtgagaa atgtagatgt gcatcgaaca atcgacgagg
    59341 cgaggttcaa caggtttcac ctgaacgtgc tgttctggtg tgcgctcgtc atcatcttcg
    59401 acggctacga cctggtgatc tacggggtcg tgctgccggt actgatgcag gagtggaacc
    59461 tgacgccgct gcaggcgggt tcgctcggca gcgcagcgct gttcggcatg atgttcggcg
    59521 cgctgatctt cgggccgctg tcggaccgca tcggccgcaa gaaggtgatc atgatcacgg
    59581 tggtcatctt cagcggcgtg accttcctca acggtttcgc gcagacgccc acccagttcg
    59641 gtgtgatgcg cttcatcgcc ggcctgggca tcggcggcgt gatgcccaac gtggtcgcgc
    59701 tgatgaccga gtacatgccg aaaaggatcc gcagcaccat ggtggcggtg atgttcagcg
    59761 gctactcggt cggcggcatg acctcggcct tcctcggcat gtacctgatg cccagctacg
    59821 gctggcagtc ggtattcttc gtcgccggca tcccgctgct gctgctgccg ctgatctgga
    59881 tcttcctgcc cgaggccgtc ggcttcctgc tcaaggaggg ccacaaggag gaggcgggcc
    59941 gcctgctcgc tcgcgtcgag ccgtcctatg cgcctgcggc cggcgacagc ttccacctcg
    60001 tcaccggcaa gggcaggagc gtggccctgg tcgcgctgtt ccagaacggc cgcctggtca
    60061 gcacgctgat gttctgggtc gccttcttca gctgcctgct gatggtgtat gcgctcggct
    60121 cctggctgcc caagctgatg aacaaggccg gctacgagct cggctccagc ctgagcttcc
    60181 tgctggtgct caacttcggc gccatcttcg gcgcgatcgg cggcggctgg ctggccgacc
    60241 gcttccacct gcgccgcgtg ctgaccatca tgttcgcgat cgcggcgctg tcgatcagcg
    60301 cgctcgcgat caggaacgac atggtcgtcc tctacctgct ggtggcgatc gcgggtgcga
    60361 ccacgatcgg ttcgcagatc ctgctctacg cctacgtcgc ccagtactac ccgctgggga
    60421 tccgctccac cggcatcggc tgggcctcgg gggtcggccg cctgggcgcg atctccggcc
    60481 cgatgctggg tggtgcgctg atctcgatgc cactggagac caacttcctc gccttcgcca
    60541 tcccgggggc gatcgccggc ctggcgatct cgatggtcgg gcgcagcgcg gtgcatgccc
    60601 cggaggagga ggagaacctc gccttcgtgg gcgagaccgg gaagctcgag gtggattgac
    60661 cggtctgtgc ggtgggcaag ttccgccgcc gctgaaaatg cgcgaacggt gctgcccgtt
    60721 cgcgcatttt cagcattgtc gatgcagctt gcgcgcgaac atcggcacga ttggcgctag
    60781 cattgcaggc ccgcccagga gatccgtcat ggagctcgaa tcctacgtcc gcgccctgcc
    60841 caaggccgag ctgcacctgc acattgaagg cacgctcgag cccgagatga tgttcgcgct
    60901 cgcccgccgc aacggcattg cgctgccctg ggcgagcgtc gaggcggtgc gtgccgccta
    60961 cgccttcacc gacctgcaga gcttcctcga cctctactac gccggcgcag ccgtgctggt
    61021 gcgcgaggat gacttcttcg agctcgcgct cgcctacttc gcgcgcgccc acgccgatgg
    61081 cgtggtccac gccgagctct tcttcgaccc gcagacgcac accgcgcgcg gggtggcgtt
    61141 cgagaccgtg ctcgacgggc tggagcgcgc ctgcgtcgag gcgcgcaggc gctggggcat
    61201 cggcgcgcgg ctgatcctgt gcttcctgcg ccacctcagc gaggaggacg gcttcgccac
    61261 gctgcagcag gcgctgcccc atctttcgcg tatcgacggc gtgggcctgg actcgtccga
    61321 gcgcggtcac ccgccggcga agttcgcccg cctgttcgcg cgctgccgcg agctcggcct
    61381 gcacgtggtc gcccatgccg gcgaggaggg gccgccggcc tacatcgtcg aggcgctcga
    61441 cctgctgaag gccgaacgca tcgaccacgg cgtgcgctgc accgaggacc ccgcgctggt
    61501 cgagcgcctc gcgcgcgcgc aggtgccact cacggtgtgc ccgctctcca acgtcaagct
    61561 gtgcgtgttc cccgacctcg ccagccacaa cctcgggcag ctgcttgccg ccggactgaa
    61621 ggtgacgatc aactccgacg acccggccta cttcggtggc tacgtggcga agaactatat
    61681 cgacaccgcg cgcgcgctcg gcctcggccg tgccgagctg cgccgcatcg cacgcaacag
    61741 cctggaggcg agcttcgtgt ccgcggccga gcgcgcgccc tggctcgccc gcctcgatgc
    61801 gctcgg
//
LOCUS       DAOTIN010000007        61419 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_460_length_61419_cov_9.300518, whole genome shotgun sequence.
ACCESSION   DAOTIN010000007 DAOTIN010000000
VERSION     DAOTIN010000007.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 61419)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 61419)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61419
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_460_length_61419_cov_9.300518"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1117)
                     /locus_tag="P5537_02000"
     CDS             complement(<1..1117)
                     /locus_tag="P5537_02000"
                     /EC_number="4.1.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004293502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HRV76846.1"
                     /translation="MNANEKFIAAKAHVDEAAIAPLPNSRKIYVEGSRPDIRVPMREI
                     SQADTPASFGAEQNPPIFVYDCSGPYSDPAAKIDIRSGLPALRQQWIEERADTELLPD
                     LSSEFGRQRAADESLDELRFPGLHRKPRRAKAGANVTQMHYARRGIITPEMEYVAIRE
                     NLNREQYIASLRASGGLKGQKMADMMLRQHPGQNFGASLPATITPEFVRDEIARGRAI
                     IPNNINHPESEPMIIGRNFLTKINANIGNSAVTSSIAEEVDKMTWSIRWGGDTVMDLS
                     TGKNIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDY
                     FTIHAGVLLRYVPLTANRMTGIVSRGGSIMAKWCLAHH"
     gene            complement(1265..2158)
                     /gene="thiD"
                     /locus_tag="P5537_02005"
     CDS             complement(1265..2158)
                     /gene="thiD"
                     /locus_tag="P5537_02005"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HRV76847.1"
                     /translation="MSSSASSAASGSASSRSSGTSSHIPNVVTIAGVDPSGGAGVFAD
                     LKAFSALGAYGCGVVAALTAQNTQAVTGVHVPPTDFLRLQIDTLFADVSIHATKIGML
                     GSAEVTTTVAERLAHWRAANVVLDPVMVAKSGDSLLAKSAISAMREALFPQAFLITPN
                     LPEAGVLLEQRAPDTVKEMYRAAERLRELLPLASERWVLLKGGHLPGNDLVDLLFDGD
                     RMVELPAQRIDTKNTHGTGCTLSSAIAALLPQAEGQFRPVETAVRHARQWLLGAIVHS
                     GELAVGSGHGPVHHFHALWKR"
     regulatory      complement(2152..2247)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            2345..4258
                     /locus_tag="P5537_02010"
     CDS             2345..4258
                     /locus_tag="P5537_02010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015437390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HRV76848.1"
                     /translation="MKNPRPLLLALLLAHFAGAACAADWQLVLSDRDRRIEIDRASIL
                     RSDAGTKVSWGRVVLTSEEAQRSGYAMIKALNRYDCRNRTFATVKRVYVDAEDNIVRE
                     EPVSAEAPIAVARNTVDERMWREVCDPPSAVELQKLAAEAARVASEQPAAPGVAPPQA
                     SAAATPAAVPPAVPVQVPAAAAQPPVPKPAESARAQSGSVRQPGEESVSAEVVRTAGG
                     GGEPAAATPALETHVEIPAKFLPGGQGAAEPESPRKSILPPLPRLSATAAPEPKAPPA
                     TKPAVRESPRAQAGGPPAPQAPAPTRSAAAPERRVVPEAEKTPASVRAEVSPARARPR
                     PQRAESAPPERPVVREKPLVARAEPATPARPTSPGARALAPKRAAVAEPSDSPAATPA
                     SARAEALRAAGIELTRLAVGMPEWSYEGETGPDNWGRMRPEWRICEEGLRQSPIDLRD
                     GIAVDLAPVQFDYRRTGFRIRDTGNTLQVEVGEGMGITVRGVRYALERFTLHRPSQDR
                     VGGMAHDMALYLQHRAEDGRMAILSLLLSAGGEANPALQTLWNNLPLDRGREFTPDAV
                     LDLPALLPAEPGHYLYTGSLPMPPCTEDVLWVVMKQPVAISADQLDVFARLYPRNGRP
                     IQPTNGRPLLESR"
     gene            4493..5605
                     /locus_tag="P5537_02015"
     CDS             4493..5605
                     /locus_tag="P5537_02015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HRV76849.1"
                     /translation="MRFRSLPSVLAGLSVLAACSAPAPHTPPPPAVLVRSVDAASAPP
                     AAQVYAGEVRARIESDLGFRIGGKLVERLVDVGAEVAAGAPLALLDAQDVRLALASAQ
                     AAAAAAESDLALARSEFARARELQARNFISSSSLDARRTALQAAEARLRQARAQAEVA
                     ANQAGYARLEAPAAGVVTAVLAEPGQVVGAGQAVLRLARPDEREVLIHVPEGRAAGLV
                     PGSAAQVRPWAAPEREYAGRVREVAPAADAATRTHAVRVAVPGADTALALGASASVAF
                     AAAQAEAPGVLLPLPAVTRQPGQADAGTVWVVGEDAAVKPLAVELGAWREDGVVVRAG
                     LPAQARVVVAGVHKLIEGMRVRAVEEGAPVLLDVRR"
     gene            5602..8832
                     /locus_tag="P5537_02020"
     CDS             5602..8832
                     /locus_tag="P5537_02020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HRV76850.1"
                     /translation="MSARGEGPIGGGRFNLSEWGLTHRSLVLYFLIVCTLIGLFSYTR
                     LGQSEDPPFTFKVMVVRAEWPGASAREIGEQVTDKIEKKLQEIAQADVIRSYSKPGEA
                     MVFFVVKDATRSRDIPDIWYQARKKIGDIAHTFPTGVRGPYFNDEFGDTYGNLFALLG
                     EGVSHAELKRHAEAIRGELLRVKDVAKVSFFAEQPQRVFVEISNTRLATLGVRLDDIV
                     AALARQNAETGAGFFETGDERIWLRPSGQFEDLDAIRATVIRAGGRSLRLGDIAEVRR
                     GYAEPPAERLRYMGQEALGIGVSMRSGGDIVALGRQLDAAVEKIDAQLPTGIRLERVA
                     DQPRAVTRAVNEFVKVLAEAVLIVMAVSLLSLGFRTGVVVLVIIPVVLAITFMFMHLL
                     DIGLHKISLGALIIALGLLVDDAIIAVEMMASKMEQGWGRVRAASYAWTSTAMPMLSG
                     TLVTAAGFLPVALAASSVGEFTRSIFQVTVTALLVSWIAAVLFVPYLGYYLLPDFSKR
                     AGKPSWLARLVGRIWPALGRRMAERDLHAHEQHDEFAIYHTPFYNRLRGVVDACVRWR
                     WVVIVLTAAIFVGSLFVFARFVPQQFFPDSTRPELLVDLRLAEGVSHHATEAAVKRLE
                     GFLDAQEGIENYVAWVGSGSPRFYLPLDQQLAQTNFAQVVILTAGLAEREALRAKLIR
                     LFEDEPWPLRGIVNRLENGPPVGFPVQYRVSGPDLAELHRRAATVAETMRANPHLSNV
                     HMDWVEPSKVVRVVIDQEKARLLGVSTQDLSSLLATSLQGMTVTQFREGTETIALVLR
                     GAERERAHLSQLPDLALPVGGGRSVPLAQVVRLEHDFEPGVIWRRNRIPTVTVRASLY
                     DGTQPAVVVGQLAPRMAELSAQLPLGYRLEVGGAVEESAKGSGSVGAGMPVFVLTVLT
                     VLMLQLKSFSRTIMVVLTAPLGLIGVAAFLLAFGKPFGFVALLGTIALSGMIMRNSVI
                     LVDQIRQDVEAGRTQWEAIVESAVRRFRPIMLTAAAAILAMVPLSRSTFFGPMAVAIM
                     GGLAVATVLTILFLPALYAAWYRVKPAAAERAERAEADRSAATALE"
     gene            8899..9552
                     /locus_tag="P5537_02025"
     CDS             8899..9552
                     /locus_tag="P5537_02025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-L-isoaspartate O-methyltransferase"
                     /protein_id="HRV76851.1"
                     /translation="MNFEKARFNMVEQQIRPWEVLDQDVLDLLMTVKREEFVPAAHRE
                     LAFADVEIPIGCGQVMLKPVIEGKILQALRVTKSDTVLEIGAGSGWFAALLAARAEWV
                     RTMEIEPELVKLASANLERNGVQNVVVVDGDGVQGWSGRAPYDVIVVSGGLPFVPQSL
                     LEQLKVGGRLFAFVGEAPVMKARLITCEAEGRFRTEDVFETVVPMLKNAPQREAFSF"
     gene            9560..9883
                     /locus_tag="P5537_02030"
     CDS             9560..9883
                     /locus_tag="P5537_02030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HRV76852.1"
                     /translation="MLQITPKMLAERLQDAQRPAPLLLDVREPWEVQICQIPGSVTMP
                     MGSVPARYPELERDRETVVICHHGGRSWQVAMFLERQGFSNVANLSGGVAGWANEVDL
                     NMPQY"
     gene            9909..11213
                     /locus_tag="P5537_02035"
     CDS             9909..11213
                     /locus_tag="P5537_02035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family outer membrane protein"
                     /protein_id="HRV76853.1"
                     /translation="MKRVLAVLVAGLFAGGAAGADLMQVYQDALANDAKFSAARAQFE
                     AGQEKVVQGRAGLLPQIGVSANTTRNDAELTPTGAAARDYSYSSNGYGVQLTQPLFRW
                     QNWVQFKQGELQTALAETQFGIARQDLVLRVAEAYFNVLNAQDALAAVTQLRTAAGEQ
                     LELAKTSFEVGTVTITDVHEAQSRFDLASAQEIAAQNQLEVARQTLAQIIGRQPEALA
                     GLREGVALQRPQPENIADWVAAAESGSFGVQAQQLAREIAAREVERARAGHLPTVDIV
                     ASHGLNNRPQPSTERSEATTIGLQLNVPLYAGGRVSSVSREAAALRLKADADLEDARR
                     SAALAARQSWLGVTSGMAQVRALEAARVSSSSALDANKLGYEVGVRINIDVLNAQTQL
                     ADTLQKLARARYDTLLAQLRLKAAAGTLGEDDVLAINALLVP"
     assembly_gap    11295..11394
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(11431..12702)
                     /gene="waaA"
                     /locus_tag="P5537_02040"
     CDS             complement(11431..12702)
                     /gene="waaA"
                     /locus_tag="P5537_02040"
                     /EC_number="2.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A) 3-deoxy-D-manno-octulosonic acid
                     transferase"
                     /protein_id="HRV76854.1"
                     /translation="MLTRLPYTLLWILALPLVLLRLAWRARRQPAYLRHLGERFGRYR
                     TRAPVGVIWVHAVSVGETRAAEPLVRALLAEWPEHSVLLTHMTPTGRETSKALFRDEA
                     RVLRAYLPYDLGCFAHAFLRHFRPLFGVVMETELWPNLLAACKRRRVPVMLANARLSE
                     RSARRYARLPALTALTLKALAAIGAQTAADASRLTQLGARRVTVTGNLKFDIAPPGAM
                     LVLGRSLRERIGNRPVLLAASTREGEEALLLDAFVRQATPEALLLLVPRHPQRFDEVA
                     ALASARGLALQRRSTEEAVRAQTRVLLGDSMGEMFAYYAAADVALIGGSWLAFGGQNL
                     IEACAVGTAVVIGPHTFNFQAVAEDAERAGAAVRAQDAEAGMRVALALVADPARRDEI
                     AAAGRAFATTHQGATARSVALLRALAVRREA"
     gene            12849..13856
                     /locus_tag="P5537_02045"
     CDS             12849..13856
                     /locus_tag="P5537_02045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase"
                     /protein_id="HRV76855.1"
                     /translation="MKILVTGAAGFIGMHATLRLLARGDEVVGLDNLNDYYDPTLKEA
                     RLARLLPHAGFRFVKLDVADRAGIEALFAAEKFDRVIHLAAQAGVRYSLQNPHAYVDS
                     NLVGFMNILEGCRHAKVQHLVYASSSSVYGGNTKMPFSEADSVDHPVSIYAATKKANE
                     LMAHTYSHLYGLPTTGLRFFTVYGPWGRPDMALFLFTKAILEGRPIDVFNHGRMRRDF
                     TYVDDIVEGVIRTLDRVAEPDPAFDPMQPNPGTGSAPYRVFNIGNHDPVELMEFVAAI
                     ENALGTTAQKNFLPLQDGDVPATYADTAALNAWTGFAPATSVREGVGRFIAWYREYYR
                     V"
     gene            13946..14743
                     /locus_tag="P5537_02050"
     CDS             13946..14743
                     /locus_tag="P5537_02050"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008803 -
                     bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="symmetrical bis(5'-nucleosyl)-tetraphosphatase"
                     /protein_id="HRV76856.1"
                     /translation="MATYAIGDIQGCYAPLDRMLELIAFDAAVDRLWIVGDLVNRGPE
                     SLRVLRFLRGLGDAASIVLGNHDLYLLMVAAGYKRRDSDDTLFQVLEADDRDELLEWL
                     SFQPLMRVQGDHVLVHAGLLPGWTVTRAQALAAEVGAALAGPKSREFLLHLAGNRPDR
                     WSDGLKGWDRLRVIVNAMTRLRFCTAQGRMDLGAKGAPHKAPPGMLPWFRVPDRFSRT
                     HTIVCGHWSALGFYREPGLIALDSGCVWGGKLTALRIEDDAVFQVPG"
     gene            complement(14760..15593)
                     /locus_tag="P5537_02055"
     CDS             complement(14760..15593)
                     /locus_tag="P5537_02055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HRV76857.1"
                     /translation="MHAGADTAPPPSSTTTPAVEAGVGAARAGAMLRATRWTRLGLHL
                     LQGVLTIAAVYPFTGRDTHQALRRRWSLGLLRVLGMRLEHRGEAVAPGCMLVANHVSW
                     VDIFAINALAPAAFVSKAEVRAWPVIGWLAAKNDTIFLRRGSRGHARIINEETAALLD
                     AGCNVAIFPEGTTTDGAALLHFHAALLQPAIACGHPVQPLALQYRTPDDRFSRTPAYD
                     GELSLGECIANIIAAPRTVARITVAAPITTADGADRRTLATRTRAEIATVIGITLDAQ
                     D"
     gene            complement(15632..16399)
                     /locus_tag="P5537_02060"
     CDS             complement(15632..16399)
                     /locus_tag="P5537_02060"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acyltransferase"
                     /protein_id="HRV76858.1"
                     /translation="MLQHLQPRQQTTARKTRNLHVGLASSETEILEAQKLRYRVFADE
                     MGARLPTRSPGVDRDLYDPFCEHLIVRDEDAGRIVGTYRILSPSAARRVGGYYSENEF
                     DLTRLQHLRGQLVEIGRSCIDADYRSGAVIALLWSGLARYMQENGYEYLIGCASVSMA
                     DGGHVAASLYNRLREKHLAPLEYHVFPRCPLPLASLRGDLDAEAPPLVKGYLRAGAWI
                     CGEPAWDPDFNTADLPILMPIGRVDDRYARHFMGRKD"
     gene            16511..16960
                     /locus_tag="P5537_02065"
     CDS             16511..16960
                     /locus_tag="P5537_02065"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HRV76859.1"
                     /translation="MPPTTPPDHDPNCVFCRIARGELPSSKVYEDADTLAIMDIQSVN
                     PGHMLVLVKPHRANVYALDDALAGAVFRTAARMARVAKKATGCQGVTLLQANEKAGAQ
                     TVFHFHIHVLPRWEGDGMELAWPVKNPPREALEEMAAKLREALAGEV"
     gene            17043..17978
                     /locus_tag="P5537_02070"
     CDS             17043..17978
                     /locus_tag="P5537_02070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase family protein"
                     /protein_id="HRV76860.1"
                     /translation="MSILVCGSVAYDSIMVFHDRFKNHILPEQIHILNVSFLVPDLRR
                     EFGGCAGNIAYGLKLLGSDPLIVATVGEDAGPYRARLRTLGLREDFVREVPGSFTAQA
                     FITTDLDDNQITAFHPGAMFHSHLNDVRSATDATLGIVSPDGADGMLRHADGFAACGV
                     PFVFDPGQALPILGSEALLKCLQQARYCTVNDYEARLMCEKTGRNEAELAREVEALVV
                     TLGAEGSRVHWRGEVFEVPAVKADAIVDPTGCGDAYRAGLLHGIAAGWDLPRSARLAA
                     VMGALKIAERGGQNYKPSRADIASRYRGAFGENPW"
     gene            17972..18445
                     /locus_tag="P5537_02075"
     CDS             17972..18445
                     /locus_tag="P5537_02075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper 2TM domain-containing protein"
                     /protein_id="HRV76861.1"
                     /translation="MVNRSRMKWRALAGAAIAVLVLGGCAQGLGGGTYSRTEARRAMT
                     VQFGTVESVRAVQLEGTKTPVGSVAGAAIGGIAGNTVGGGRGQAIATVIGAVAGGLAG
                     SAVEEGATRQPGVEVTVRLDNGQFLAVVQADEGERFRLGERVRILRDAGTTRVSR"
     gene            complement(18476..19663)
                     /locus_tag="P5537_02080"
     CDS             complement(18476..19663)
                     /locus_tag="P5537_02080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3426 domain-containing protein"
                     /protein_id="HRV76862.1"
                     /translation="MMITRCPACQTVFRLRPEQLHARGGEVRCGHCFHPFNALENTVE
                     VRDDVTATAPPPPPPAARPVRETRPDPLLDFDIPEVAPSPPIRAPQPDLDDYEDWLAP
                     PPRSVTSPAPAEDGAGADVGLSPDESTASPPPFPEVLRSARRGPSSRDDEGRPHGRGM
                     TVAEDTAFAPTISYAPPPHFDDEPATEIPGLAESPPEPRHPEPEPVPAHEEEVAPFAP
                     EPDLARLDANYGRPRKEIHPLFRALAWLLTVGLSALLAAQATYLYRMEIARALPGLRP
                     ILSEACARLGCSVPYPRDAEHIAIEASDLQAEPGRPGYYLLQATLNNRGDYPQQWPHL
                     ELTLTDAGDNPISRRVLPPSDWLPPTQPREAFTARSAIELRIPFAAPALAPTGYRIYA
                     FYP"
     gene            complement(19660..20562)
                     /gene="prmA"
                     /locus_tag="P5537_02085"
     CDS             complement(19660..20562)
                     /gene="prmA"
                     /locus_tag="P5537_02085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HRV76863.1"
                     /translation="MWISVTLQAEADKAEALSDALMEAGALSVSIEDADAGTEAERPQ
                     FGEPGHLPTALWDHSRVIALFDAAADPAELGAMLAEAARAAGFDAVPPFTTETVAEQN
                     WVQLTQSQFDPIRITDRLWIVPSWHEAPDADAINIELDPGMAFGTGSHPTTRLCLEWL
                     CEAVVPGCSVLDYGCGSGILGIAAAKLGAGEVLGIDIDEKAVDAARDNAARNHADMRL
                     QHSAVPLGDAFDLVVANILTNPLCVLAPAISARVAPGGRVALSGVLETQAAQVIEAWA
                     PYIALHVGAAHEGWIRLEGRRPGP"
     gene            complement(20569..21927)
                     /gene="accC"
                     /locus_tag="P5537_02090"
     CDS             complement(20569..21927)
                     /gene="accC"
                     /locus_tag="P5537_02090"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004373979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HRV76864.1"
                     /translation="MFEKILIANRGEIALRILRACRELGIKTVAVHSEADTHAKYVRL
                     ADESVCIGPPPSAQSYLNVPAIISAAEVTDAEAIHPGYGFLSENADFGERVEQSGFVF
                     IGPRPETIRLMGDKVSAKDAMKAAGVPCVPGSEGALPEDPKEIVKVARAVGYPVIIKA
                     AGGGGGRGMRVVHTEAALLNAVTTTRAEAQAAFGNPVVYMEKFLENPRHVEIQVLADQ
                     HGNAVYLGERDCSMQRRHQKVIEEAPAPGIDRKAIAKVGERCAEACRKIGYRGAGTFE
                     FLFENGEFYFIEMNTRVQVEHPVTELITGIDIVQAQIRIAAGEKLWFRQRDIEFRGHA
                     IECRINAEDPFKFTPSPGRITNWHTPGGPGIRVDSHVYNGYTVPPHYDSMIGKLIAFG
                     DTRDQAIRRMRIALSEMMVEGIKTNIPLHQTLMLDPRFNEGCTSIHYLEHKLADRNEV
                     RS"
     gene            complement(21935..22378)
                     /gene="accB"
                     /locus_tag="P5537_02095"
     CDS             complement(21935..22378)
                     /gene="accB"
                     /locus_tag="P5537_02095"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HRV76865.1"
                     /translation="MDLRKLKKLIDLVQESGISELEVTEGEEKVRIAKHSTAAPATYY
                     AQVPPAAAPAPLAAPAPADVEDELPDGHIVKSPMVGTFYRASAPGAKPLVELGQKVAS
                     GERLCIIEAMKLMNEIEADASGVVKAILVENGEPVEYGQPLFVIG"
     gene            complement(22823..23443)
                     /locus_tag="P5537_02100"
     CDS             complement(22823..23443)
                     /locus_tag="P5537_02100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004381591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76866.1"
                     /translation="MPSHAHVSRSGGLRREIAALAARMMAEDGISDFGFAKRKAAKQL
                     GATEADALPNNTEIEAELRAWLAIYQDEEQPQRLLEMRSAAVEVMRLLADFRPYLTGG
                     ALDGTAGRYSELEIELFPESAKDVEIFFLNQDFAYEHREPRRPAPHTPEAILGFDWDD
                     VPVKVSIYPSAAERSPRRGQERARLAQVEALVAAAESTIAPHPSAP"
     gene            23528..24874
                     /gene="mpl"
                     /locus_tag="P5537_02105"
     CDS             23528..24874
                     /gene="mpl"
                     /locus_tag="P5537_02105"
                     /EC_number="6.3.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004381592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-
                     meso-diaminopimelate ligase"
                     /protein_id="HRV76867.1"
                     /translation="MHIHILGICGTFMGGVALLARAAGHTVTGCDANVYPPMSTQLEE
                     QGIGLIEGYDSSQLDLEPDVYVVGNAVSRGNPLLEAILDRGLPYVSGPQWLAEHVLAG
                     RWVLAVAGTHGKTTTTSLLAWILEDAGLSPSFLVGGVPQNFGVSARLTESPFFVIEAD
                     EYDTAFCDKRSKFVHYRPRTAILNNLEFDHADIFADLGAIETQFHHLVRTIPASGRIV
                     ANAHEDSLRRVIERGCWSELEWFGGDGRWAVATGADEVEAVFRLDGVEQGRVRMPLAG
                     SHNRDNALAAIAAARHVGVTPAQAIASLGRFAGIKRRLELRGTVRGVRVYDDFAHHPT
                     AIALTVGGLRRREPQGRILAVLEPRSNTMKLGVMKAQLPASLAEADLVFCHAHGLGWD
                     AAEALAPLGARARSYDRLDALVADVVAAARPGDHVLVMSNGGFGGVHQKLLDALGT"
     gene            complement(24936..25595)
                     /locus_tag="P5537_02110"
     CDS             complement(24936..25595)
                     /locus_tag="P5537_02110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BON domain-containing protein"
                     /protein_id="HRV76868.1"
                     /translation="MNQPQHRDRPAKSSRRALLLGLSAAIALPLLQGCFPVVATGVGA
                     GAAMVSDRRTSGTYVEDEGIEWKVSARIRERLGDSVHVNVTSYNRNVLLTGEAPNETV
                     RGQLDGIVAGVEHVRGVVNEVAIAPNSNLTARGNDTLITSNVKARMIDAGTVSAHNIK
                     VVTEANVVFLLGIVTRSEADAAAEVARTSQGVRKVVRVFEYISDEEARRLDNPTGARR
                     N"
     gene            complement(25595..26188)
                     /locus_tag="P5537_02115"
     CDS             complement(25595..26188)
                     /locus_tag="P5537_02115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004381594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HRV76869.1"
                     /translation="MNLIDRISHQFEDNMRASLEALELLAAPIAGAVELITASLLDSG
                     KVLVCGSSGSAGDARRFAAQLVNGFELERPALAAMALSADSSSLAPVAGDPDTQALFA
                     RQIAAFGQPGDILLTLSANPDSSRILDAIRAAHERDMRVIALTGAGGGSTAATLGPAD
                     ILLCTPDERVARIREIHLLILHCLCDGIDCLLLGVED"
     gene            complement(26234..26686)
                     /locus_tag="P5537_02120"
     CDS             complement(26234..26686)
                     /locus_tag="P5537_02120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004381595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HRV76870.1"
                     /translation="MGGRSGGWTRGAGEDDRGAHAGADSIGARPTPAQAHGAAAEALA
                     AEHLAAHGLRVIARNVRCRGGEVDLVCLDRSHVVFVEVRLRRNGRFGGAAESITAAKQ
                     RRVLIAAQWWLGGAGRRFRDAPCRFDAVLLDALDPARVTWLPGAFDAG"
     gene            26685..27572
                     /gene="rsmI"
                     /locus_tag="P5537_02125"
     CDS             26685..27572
                     /gene="rsmI"
                     /locus_tag="P5537_02125"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HRV76871.1"
                     /translation="MTTSAPLPDRPLSSTPSLYVVATPLGNLHDITLRALAVLAAVDV
                     VAAEDTRHSQRLLDAHGIRARMLAVHQHNEQEAAGAIVAELAAGRQVALVTDAGTPAV
                     SDPGARLVARVRAAGHPVVPLPGPCAAVAALSVSGFAEGGFRFVGFLPAKGGARAAAL
                     RELADERAAMVFYEAPHRIAECMADMEQAFGGVRELLIAREMTKLHEQIVRMPLAQAA
                     AWLAADTNRLRGEFVLVVEGAPAGEAVDANARRVLELLLAELPLKGAARLAAEITGAP
                     RKALYALALERKGGDSPAA"
     gene            27647..28687
                     /gene="pyrC"
                     /locus_tag="P5537_02130"
     CDS             27647..28687
                     /gene="pyrC"
                     /locus_tag="P5537_02130"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HRV76872.1"
                     /translation="MQSITLIRPDDWHLHVRDDAALDAVVPHTAARFGRALIMPNLKP
                     PVTTTAQALAYRERILAAARGSRFEPLMSLYLTDNLSPDEIDRASASGHIVACKLYPA
                     GATTNSDAGVTAIDKVYPVLERMEKLGMVLCVHGEATGAEVDVFDRERVFIERTLSPL
                     VRRFPGLKVVFEHITTAEAAQFVRAAGSHVAATVTAHHLLLNRNAIFSGGIRPHHYCL
                     PVLKRESHREALVAAVTSGNARFFLGTDSAPHARSTKENACGCAGCYTAHAAIELYAE
                     VFDAAGALDRLEAFASLNGPAFYGLAPNADTITLRREPWSVPASYPYLGEDPLVPLRA
                     GEQVGWKLVGGA"
     gene            28689..29195
                     /locus_tag="P5537_02135"
     CDS             28689..29195
                     /locus_tag="P5537_02135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76873.1"
                     /translation="MGVRMHEAGIRDAAARVATARRGVRCGAGGALRRGLAAVGLLAV
                     LAGCENSATAYMIEGSQHALILVREQKFFWDDELRQAVVVSRLPACQKRIRIHPSSTT
                     LVEMKVYAAGDGLWALHQGVRWYLAGTEECRLQDWDNPGDRPPGALLGSFALKDGEPA
                     FVAAPAAK"
     gene            29236..29617
                     /gene="rnpB"
                     /locus_tag="P5537_02140"
     ncRNA           29236..29617
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="P5537_02140"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            29977..30420
                     /gene="mraZ"
                     /locus_tag="P5537_02145"
     CDS             29977..30420
                     /gene="mraZ"
                     /locus_tag="P5537_02145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004341928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0051302 - regulation of cell division
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HRV76874.1"
                     /translation="MFQGAVALNLDAKGRLAIPARHRDALAVDNGQVVLTAHPHGCCL
                     VYPVPAWNPIRDHVLRAPSLDPQAAMLKRLLVGFAQEETLDAAGRVLVASSLRKFAAL
                     EKQVWLVGQGTHFELWSDERWEKQQQAMLDLVNTGLPPGFESLAL"
     gene            30417..31352
                     /gene="rsmH"
                     /locus_tag="P5537_02150"
     CDS             30417..31352
                     /gene="rsmH"
                     /locus_tag="P5537_02150"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HRV76875.1"
                     /translation="MTSAHAHVSVLLSEAVDALAIRADGIYVDGTFGRGGHSRAVLAQ
                     LGPQGRLIAFDRDPAAIAAGEAVGDARLTLVHSAFSALDDELVRLGVQAVDGVLLDLG
                     VSSPQLDDAARGMSFRFDAPLDMRMDTSRGQTVAEWLAEASVGQITEVIREYGEERFA
                     HAIAKAIATARAGGAVATTGQLAALVEKAVRTREPGQHPATRTFQALRIFINQELKEL
                     SGVLPVCVSRLRPGGRLAVISFHSLEDRIVKRFMRDESRPPLLPRRLPVRAADLPAPR
                     LRLVGKATRPGEAEVAANPRARSAVLRVAERTEAP"
     gene            31352..31618
                     /gene="ftsL"
                     /locus_tag="P5537_02155"
     CDS             31352..31618
                     /gene="ftsL"
                     /locus_tag="P5537_02155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HRV76876.1"
                     /translation="MVRIDAVLVALAVASALGVVASQHQARRLHGEYEREQARAQALE
                     VEWGQLQLEQSTWATHGRVEKLARDRLHMQVPPEGQVLVVEPQS"
     gene            31615..33381
                     /locus_tag="P5537_02160"
     CDS             31615..33381
                     /locus_tag="P5537_02160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HRV76877.1"
                     /translation="MKKQRTVTFNHNPLLKRELPAWRPRIVMLALMGCSLALVGRALY
                     LQGVNDDFLQAKGASRYARVLEVPATRGRITDRHGDILAVSTPVRAVWALPADARLEP
                     AQVRELARLLEMDANELNGKLAAGRDFVYLKRQVPPEVAQAVADLRLPGIHQQKEYRR
                     YYPGGEVMAHILGFTDLEDRGQEGIELAFDKRLSGRAGARRVIKDRRGQIVEDVEAIR
                     PPRDGDDVALSIDGKIQYLAWSALREAMEEHKAKAAAAVVLDVRSGEVLALVNAPTFN
                     PNNRANLTGAQLRNRVFTDAFEPGSVMKPFIAALALERGKVRLNTPIDTGSGRMTIGT
                     ATISDTKRHGVITMAQVVQKSSNIGTVKMAQQLGADEMWHLFDQLGFGTPLNLGFPGE
                     TSGRLRPAKSWRPIEQATMSYGHGISTSLIQMARAYLVFAREGELVPLSLTRVEGAPS
                     SGRRVFSVDTARQMRTVLAMAAGPGGTAIRAQVPGYTVAGKTGTAHKLEDGRYARKYI
                     SSFVGFAPASDPRIVVAVMVDEPSAGHHYGGTVAAPVFSRITEGTLRTLGVAPDMPLT
                     PLQLARRGADEAASAGVGRENM"
     gene            33378..34883
                     /locus_tag="P5537_02165"
     CDS             33378..34883
                     /locus_tag="P5537_02165"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HRV76878.1"
                     /translation="MSAAQALAVLDRLRALGVHADDISADSRRAGSGCVFAAWPGQRT
                     DGRRFLADAAARGVAAVLWEDGDGFAAPPLAVPGFGVRGLRELAGYLAHELHGRPSQA
                     LWLAGVTGTNGKTTVSQMLARALGDLGQPCGIVGTLGCGFPDALEEGLNTTPDALELQ
                     RWFARFRDQGAVAAAMEVSSIGLDQGRVNGAQFDVAIFTNLSRDHLDYHGTMEAYAEA
                     KARLFERPELAACVINVDDPWGLALARRLVAAGRTVIACTLYAANADAVPGARVLRAD
                     RLQAAPAGLRFTLVWEGREAEIGVRMVAHFNVSNLIAVAGALLARGIAFDELPPVLGR
                     LSPPQGRMQLVGGVCEPLVVIDYAHSPDALAKVLEALRGTVHSRRGRLTCVFGCGGDR
                     DPGKRPLMGEIASAIADRVVITSDNPRSEDPQRIVEAIAAGAGPAAERVVDRAQAIAR
                     AVAEAQADDVVLIAGKGHEPYQEILGKRLPFSDLEQAKRALAAWHAREKGQ"
     gene            34880..36292
                     /gene="murF"
                     /locus_tag="P5537_02170"
     CDS             34880..36292
                     /gene="murF"
                     /locus_tag="P5537_02170"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004375113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HRV76879.1"
                     /translation="MMSLHDAARALAVHGARATGEGRFDSVGTDTRALAPGQLFVALR
                     GERFDGHDFVATAAKAGAAAALVDAAWVAGKSDAGLPLLVVDDTRRALGTLAAAWRAR
                     FALPLIGITGSNGKTTVKEMCAAILRAQASRDGFGEESVLATRGNLNNDIGMPLTLLE
                     LRDFHRAAVIEMGMNHPGEIGYLSALAQPTVALVNNAQRAHLQGMGSVDEVAREKGAI
                     YDGLGGAGVAVINADDPHAGYWRALNAGRPIVTFGIDQPADVFARCTLRGLGSRLELD
                     APQGKIDFTLQVPGLHNVRNAIGAAAACLSAGVSPEAVAQGLAGFAGTRGRLQRRAGP
                     QGALVLDDSYNANPDSVRAGIDVLAAMPGHTWLVLGDMGEVGETSAQVHDEVGGYAKS
                     KGIDGLFALGDMSAVAAHNFGEGARHFSSAEALVKALAPHLDADSVVLVKGSRFMRME
                     RVADALAAMHNPAPSTETGS"
     gene            36294..37382
                     /gene="mraY"
                     /locus_tag="P5537_02175"
     CDS             36294..37382
                     /gene="mraY"
                     /locus_tag="P5537_02175"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HRV76880.1"
                     /translation="MLLELALWLSQDIRGFNVFGYITLRTVLAALTALAISLIAGPAV
                     IRWLAAKKIGQAVRDDGPKSHLTKAGTPTMGGALILIAIGITVLLWGDLRNDYVWVTL
                     LVTLGFGAVGWVDDWRKVVHRDPKGLASRWKYLWTSAIALAAAIYLGISADTPAETEL
                     IVPFFKAVAYPLGIFGFVALTYFVINGTSHAVNLTDGLDGLAIMPTVMVAGALAIFAY
                     VAGHAGFSKYLGVPYVAGAGELAVFCGAICGAGLGFLWFNAYPAEVFMGDVGALALGA
                     ALGTIAVIVRQEIVLFIMGGLFVAETLSVMVQVLYFKATGGKRIFRMAPLHHHYELGG
                     WKETQVVVRFWIITIMLVLFGLSTLKLR"
     gene            37379..38779
                     /gene="murD"
                     /locus_tag="P5537_02180"
     CDS             37379..38779
                     /gene="murD"
                     /locus_tag="P5537_02180"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HRV76881.1"
                     /translation="MSALTGKHILVLGLGESGLAMARWCALRGARVRVADSRALPPGR
                     DALKADAPLAELFVGGFGDEVLDGVDLVALSPGLDPRVGVAAEARRRGLPLTGEMSLL
                     AQALDELGVRAQTCILAITGTNGKTTTTALAAALAQSAGLDAVAAGNISPAALDVLME
                     RLEIGAALPACWVLELSSFQIETMQGLDAEAATVLNVTDDHLDRYADLEEYAATKAAI
                     FQGAGVQVLNREDARVVAMALPGRRTLRFGTTAPAADSDYGLADHDGRAWLMRGSERL
                     LAPDELPLAGRHNAANALAALALCEGGLGIEPQALIPGLKAFRGLPHRVELVAERADG
                     VRFYDDSKGTNVGATVAALAGMDCPVVLIAGGDGKGQDFSPLAPVLAGKARALLLIGR
                     DAGRIDQAVAGCGVAIEHAPDLDAAVVRANAFARAGDAVLLSPACASLDMFRNYAHRA
                     EVFVAAVRRLPGVSPR"
     gene            38776..40005
                     /gene="ftsW"
                     /locus_tag="P5537_02185"
     CDS             38776..40005
                     /gene="ftsW"
                     /locus_tag="P5537_02185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004378960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative lipid II flippase FtsW"
                     /protein_id="HRV76882.1"
                     /translation="MKFASTLTGLLQRGGGAPDPARAAADRLGRHGAPARELDLLLIW
                     SAVGLLLLGLVMVYSASIAIAEGSRFTNYQAHFFLLRHAVFLAVGIGLGLVAFQLPMA
                     RWQQLAPALFVAGVVLLVVVLIPGIGREVNGAQRWLSLGPVNLQPSELMKIFAALYAA
                     DYTVRKLDVMGSFMKGFVPMMAVILLVGFLLLREPDFGAFVVITTIAFGVLFLGGVNV
                     RVFVLLAVVAVIGFVILIWTSPYRRDRIFGFMDPWQDAYGKGYQLSHSLIAFGRGEWF
                     GVGLGGSVEKLFYLPEAHTDFLLAVIAEELGFVGVLTVVALFALIVHRAFIIGREAVK
                     LERYFAGLVAQGIGLWIGIQSFINMGVNMGLLPTKGLTLPLMSFGGSGIVANCVALAI
                     LLRVDWENRQLMRGGRT"
     gene            40002..41072
                     /gene="murG"
                     /locus_tag="P5537_02190"
     CDS             40002..41072
                     /gene="murG"
                     /locus_tag="P5537_02190"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HRV76883.1"
                     /translation="MKTLMVMAGGTGGHIFPGIAVAEELRARGWRIVWMGNPEGMEAR
                     IVPPRGYDTAWVRFGALRGKGLLRKLMLPVNLLSGFWQALRELRRVRPDVVLGMGGYI
                     TFPGGMMAALLGRPLVLHEQNSVAGLANRVLARVADRVLSGFPAVLEKAEWMGNPVRA
                     DIAAVLPPAERMAGREGPLRVLVVGGSLGAAVLNETVPQALLRLPAEQRPTVVHQAGE
                     RQIEALRAAYARAQVEGELRPFIDDMAAAYADADLVICRAGALTVAELAAAGVASLLV
                     PFPYAVDDHQTGNARFLADRGGAYLLPQSELTPDRLAGILSSLDRGRLLQMAENARAL
                     AKPLAAVAVAHVCAELGGGEQA"
     gene            41069..42484
                     /gene="murC"
                     /locus_tag="P5537_02195"
     CDS             41069..42484
                     /gene="murC"
                     /locus_tag="P5537_02195"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011236642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HRV76884.1"
                     /translation="MKHKVRNIHFVGIGGSGMSGIAEVLANQGYRVSGSDLGDNAATR
                     RLQKMGAHVVRGHDAGNVADADVVVVSTAVKADNPEVVAARERHIPVVPRAQMLAELM
                     RFKHGIAIAGTHGKTTTTSLVASILAEGGIDPTFVIGGRLNAAGANARLGTGDYLVAE
                     ADESDASFLLLNPVISVVTNIDADHMDTYGHDFGRVKQAFVDFLHRLPFYGVAVLCED
                     DPNVRGIMPQVAKQIVRYGLSETANIRAENVRADGGRMLFDCVRVNGTTSRLSIELNL
                     PGLHNVLNALAAIAVATEVQVPDAAIIKALAEFNGVGRRFQRYGEVALLDQDGDEAGS
                     FTLVDDYGHHPVEMAATIAAARGAFPGRRLVLAFQPHRFTRTRDCFEDFVKVLSTVDA
                     LLLAEVYAAGETPIVAADGRSLARAIRVAGTVEPVFVEEIAEMPRVILSAARDGDVVI
                     TMGAGSIGAVPGKLASIEEAV"
     gene            42481..43395
                     /locus_tag="P5537_02200"
     CDS             42481..43395
                     /locus_tag="P5537_02200"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HRV76885.1"
                     /translation="MKARFGKVAVLFGGSSAEREVSLMSGRAVLAALQSAGVDAHAFD
                     PAERDLHILKEEGFERAFIALHGRGGEDGTVQGALELMGIPYTGSGVMASALSMDKWR
                     TKMVWLSASLPTPRYAILEHDTDWDAVVAELGLPIFVKPVHEGSSMGATKVVEVSQLR
                     AAWELAARYDSLVIAEEFIAGAELTAPFLEDRALPLVRIVAPDGNYDYQHKYFTDDTR
                     YDCPCGLPAAQEAELQALVMKCARVLGCRGWGRADLILSEDGRPYLLEMNTSPGMTGH
                     SLVPMSARVAGMDFTSLCLEILQGARLG"
     gene            43388..44251
                     /locus_tag="P5537_02205"
     CDS             43388..44251
                     /locus_tag="P5537_02205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HRV76886.1"
                     /translation="MAEAGIRPASIRSARRPAAGGPARAGVERGLWHRPALLNLISDL
                     LTLGAAVALGWALVIWFVSRPLFPLRELVVLTEPSQVTAEQLDYAARLAVQGNFFTVD
                     LDGVKQTFEKLPWVRKAEVRRRWPDALELRLEEHEAVAYWTVSESGEARLVNRQGEVF
                     VAASNADMPQFDGPQGSASWLLARHAEFSDMLQPLGVRLVGLALSAREAWRLQLDNGM
                     TIVLGREQDKSPLMDRLRRFIAVWPRVHEQIDIDIKTADLRYASGFALTPADASVLQQ
                     PVAPAARKGRK"
     gene            44248..45477
                     /gene="ftsA"
                     /locus_tag="P5537_02210"
     CDS             44248..45477
                     /gene="ftsA"
                     /locus_tag="P5537_02210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019921436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HRV76887.1"
                     /translation="MSKQYNELIVGLDIGTAKVTCMVAEVKPDGRLNVVGLGTQPTNG
                     LKRGVVVNIEATVDAISRVIQEVEVMADCKIHEVYTGLAGSHIKSFNSSGTVAIKEKE
                     VSPLDVERVIEVARAMPIPAEQQILHILTQEFIIDGQGGVREPIGMSGVRLEVKVHIV
                     TGAVSAAQNVIKCVRRCGLEVMDLSLQPLASSHAVLTEDEKELGVCMVDIGGGTTDIA
                     VFTQGAIRHTAVIPVAGDQITNDIAMALRTPTAEAEEIKIRHGVAMHHMADPEEMIEV
                     PGVGDRPPRKLSRQALADVIEPRVSELFELVQAELRRSGYEELLSSGIVLTGGSAVMR
                     GMAELAEDVFHMPARVGAPQYDGGLADVVCQPRYATAMGLVMEGAVQRRRGLQARDTR
                     SVKQFFGRMKAWFERNF"
     gene            45619..46761
                     /gene="ftsZ"
                     /locus_tag="P5537_02215"
     CDS             45619..46761
                     /gene="ftsZ"
                     /locus_tag="P5537_02215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HRV76888.1"
                     /translation="MFEIVEKEATGTVIKVVGVGGAGGNAVDHMIREGVKGVHFISAN
                     TDAQALKRCLAPVKVQLGNTGLGAGSKPEAGRAAAQESRDAISAALEGAHMVFITGGM
                     GGGTGTGAAPVVAEIAKEMGLLTVAVVTKPFDFENRIRVAESGIEELTRHVDSLIVVL
                     NDKLLEVFGDDAGFEECFRSADNVLRSAVGGIAEIINVPGLVNVDFQDVRTAMAEMGR
                     AMMGSAEAAGMDRARIAAEQAAVSPLLEGTELSGARCVLINITASKSLKMSEVRDAVR
                     TVQAFAAPEAFVKYGTVFDDTMEDRIRITVVATGLGAPRAARQPVMQVVQGTGTYGPS
                     MGGAVDVTNLDVPAVMRSGRRTTVEAMSTSGVGTYDIPAFLRRQAD"
     gene            46960..47886
                     /gene="lpxC"
                     /locus_tag="P5537_02220"
     CDS             46960..47886
                     /gene="lpxC"
                     /locus_tag="P5537_02220"
                     /EC_number="3.5.1.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002932254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008759 - UDP-3-O-[3-hydroxymyristoyl]
                     N-acetylglucosamine deacetylase activity [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-acyl-N-acetylglucosamine deacetylase"
                     /protein_id="HRV76889.1"
                     /translation="MIRQRTLKSVVKATGVGLHGGRKVTLILRPAAPDTGIVFHRVDL
                     DPPLSLPADPYAVCDTRMCSGLEQGGHKVGTVEHLMSALAGLGIDNLHVDVDAPEIPI
                     LDGSSAPFVFLLQSAGIEEQKAAKKFLRVKKPVEYVEGDKWVRLEPHDGFRLAFSIVF
                     NHPAIDSTSTRVEVDFARHSYVRDVARARTFGFMQDVEFMQANGLALGGSLENAIVMD
                     EYRVLNVEGLRYADEFVKHKVLDAIGDLYLCGHPLLASYSAHKAGHALNNQILRVLLE
                     DKEAWELVSFDQEAATPPAVSHQFAPLAAAFA"
     gene            48017..48205
                     /locus_tag="P5537_02225"
     CDS             48017..48205
                     /locus_tag="P5537_02225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004306278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76890.1"
                     /translation="MLIMRLLLLLAVLSIGGSAILWLLTGNPRYKAWAWKAFRATLVM
                     LFVLFALFAIERVLAPVA"
     gene            complement(48284..48451)
                     /locus_tag="P5537_02230"
     CDS             complement(48284..48451)
                     /locus_tag="P5537_02230"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76891.1"
                     /translation="MKHASEADLRACRRSYMNRRASAPCRSGGSRESGRSVIDACQSP
                     AAAIAPAGAPT"
     gene            complement(48501..48923)
                     /locus_tag="P5537_02235"
     CDS             complement(48501..48923)
                     /locus_tag="P5537_02235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DciA family protein"
                     /protein_id="HRV76892.1"
                     /translation="MTRPLSRFLGGDALARLQDHAARLNRLQAVLDGMLPPQLQGQCR
                     VANLKEGSLVVAARGGAAAVRVRQILPSLLERLQHGGHPVQSIKVKVGTPEQMAPERP
                     APQRQISESAKADLHDFADTLPADSPLRASIERLIRRA"
     gene            49008..51737
                     /gene="secA"
                     /locus_tag="P5537_02240"
     CDS             49008..51737
                     /gene="secA"
                     /locus_tag="P5537_02240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HRV76893.1"
                     /translation="MISGLLKKIFGSRNDRLVRQYMHTVRKINALEAEISALSDEALR
                     GKTAEFRERVANGESLDALLPEAFAVVREAGKRVHGMRHFDVQLVGGMVLHNGKIAEM
                     RTGEGKTLVATLPAYLNALSGRGVHVITVNDYLASRDAEWMGRIYGFLGLTTGCNLSR
                     MSHDQKQAAYAADITYGTNNEFGFDYLRDNMVYAVGERVQRALNFAIVDEVDSILIDE
                     ARTPLIISGQAEDHTELYLKMNQVAPMLKRQEGGLDDKDEVIEAGDYTVDLKSHQVLL
                     TEAGHETAEQILVRMGLLAEGGGLYDPGNILLVHHLYAALRAHALYHRDQQYVVQNGE
                     VVIVDEFTGRLMPGRRWSDGLHQAVEAKEGVRIQAENQTLASITFQNYFRMYGKLAGM
                     TGTADTEAFEFQQIYGLETVVIPTNRPTRRKDENDKVYRTANEKWNAVIEDIRACVER
                     GQPVLVGTTSIETNEFLSGVLKKAKIEHQVLNAKQHDSEAQIVAQAGRPGMVTIATNM
                     AGRGTDIVLGGNIEKPVAAVRDDATLDPAQREATIVALREAWQKVHDEVIAAGGLHII
                     GTERHESRRIDNQLRGRSGRQGDPGSSRFFLSLEDPLMKIFAGERLNAIMVRLKMPEG
                     EAIEHAMVTRSLESAQRKVEQRNFDIRKQLLEYDDVANDQRKVIYQQRNELLESEDIS
                     DTVRAMRQGVLHDIFRRYVPVDSVEEQWELSALEQALLAECQLKLSVAEWVKAEPSLD
                     DDAILERLVQAGEEAYAAKTAIVDPAAWHQFERNVMLQSLDTHWREHLAALDHLRQGI
                     HLRGYAQKNPKQEYKREAFELFETLLDTVRTDVTKILMTVQIRTEAQLEEAETPQQVE
                     NVQYRHADYDEALGGDAEQAGAQPAAAGPKVGRNDPCPCGSGKKYKHCHGKLN"
     gene            51760..52998
                     /gene="argJ"
                     /locus_tag="P5537_02245"
     CDS             51760..52998
                     /gene="argJ"
                     /locus_tag="P5537_02245"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004306284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004358 - glutamate N-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HRV76894.1"
                     /translation="MAVNLATPNPAELLPVRGVRLGVTEAGIRKANRRDLTVIELAEG
                     SRVAGVFTQNRFCAAPVQVCRRHLAGGAIRALLINTGVANAGTGEPGLANANACCAAL
                     ASAMGIEAGQVLPFSTGVILEPLPVDRVVAGLPGAVANLRADGWFDAAHAIMTTDTLA
                     KAVSRQVRIGERMVTLTGISKGAGMIKPNMATMLGFLACDAAISQDLLDGLVREAADL
                     SFNSITVDGDTSTNDSFILIATGGAGNAEISAADSEDYRALRAAVIEVAVGLAQAIVR
                     DGEGATKFMTIAVEGGRDREECRKVGYAVAHSPLVKTAFFASDPNLGRILAAIGYAGI
                     DDLDVAKLRVWLGNPEESVLVAEHGGRAASYLEEAGSRIMKHAELTVRIALARGDAAA
                     TVWTCDFSYDYVKINADYRS"
     gene            53205..55268
                     /locus_tag="P5537_02250"
     CDS             53205..55268
                     /locus_tag="P5537_02250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004306286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HRV76895.1"
                     /translation="MQEKFALCRPRARSLASRAGPVLLLGLLALDARAERGEADPFFG
                     AIPMVLTASRLAQSPLDAPAPVTVIDREMIVASGFNEIHDLLRLAPGFLVADHPDGPP
                     AVASHGLGDAHARRIKVMVDGRTINSPLWGNVIWDNLPLRVDDVERIEVVRGPNGAAY
                     GVNAFQGVVNIITRAPSTESGRAFVVRAGKNGFRDYGVRLNGAGGSAFDWRLSASRRE
                     LTTFEPHFRQRLGDWHSSESLTRNTAHFSSVLQVSTLDELGFQVGVSEGRSKRGAEAY
                     LDYPRHAEDDRALHLQAGWRRQVDAESVLSLQYFHQAERARGNWAVTQRHPTDPAMVV
                     RFPSSRDSEARRHDLELQYDTRLARRLTGMLGIGLRSEHARSTHLFGTGRWLDATHGQ
                     IFGSLTWNPLEPLKIDLGGTLEHHDYSGRLFSPRLAMNYALDADSALRLSTGTAYRAP
                     SLMESRAFQTDREGDTIRRIGFRVFEPLQSERMRFVDLGYVAQLRPLGLNLDARIFRE
                     HYRRFIDDKSCIFGECPGTEPAAYVPIDPGKKSFYFLNASDFRMTGAEFTLDWRKLGW
                     GRAVLSQAFIRIDHGEPYSDRDIPNSAPHSTTSLLLIKDLPGRWQASLGYYHNGLYYW
                     MNGGDIVPRIDRFDLRIARRFGPPGSDNEVSLTALSLKGRYADFHEDKFRHEPDLYLG
                     VRIGW"
     gene            55262..56233
                     /locus_tag="P5537_02255"
     CDS             55262..56233
                     /locus_tag="P5537_02255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004306287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate binding protein"
                     /protein_id="HRV76896.1"
                     /translation="MVTSVIRALVSRLLPGCQRVALVLAMLGLLPGPDGFSVQAQAME
                     VAVLLSEAEGRGQRFAEALDAALAPGMHRLVAAGVAGVQADAALLGRADLVLAVGQAA
                     AEHALRASAQPVLAVLVGLRDVDRLNGAHPGRGLGALVLDQPLERHLRLVRAVLPDAK
                     RVGVLLGPDSVLQLPGLPGAADACQLQADVHEVRQPADLVPALDHLLFAGDALLPLPD
                     GLVSGPAAARTILLTSYRHRRPVFAHSAAYVTAGALAAVFSTPEHVAMDVADLLAGAA
                     EPSAMVRKIHPPRRFDVAVNRAVARALGLVVADEKALRERIANGGEQ"
     gene            56230..57546
                     /locus_tag="P5537_02260"
     CDS             56230..57546
                     /locus_tag="P5537_02260"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009975 - cyclase activity [Evidence IEA];
                     GO_process: GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HRV76897.1"
                     /translation="MIGALARCSLRRQMLLVLGLPSVILVLCIAALFAYQSSRALDQA
                     LLERGRAMVRFLAPAAEYVLVSGNREALAALMARVQAQPDVIGVGFYDPAGEVLVMRG
                     EGVSPRLAAPVREDGDEIRVALADAAIGFEAPVVVVPAAVDDYATRPAAKTVEVIGGV
                     RVVLGTARLDAEKRAVFLTVSALVLGVLSAAMVVAVRLAGSVGEPVAALVDAVGRMAD
                     GDLAVRVPARARNGELKALEAGFNAMAEAIAENQRTLQARVDEATVQLAWQARHDPLT
                     GLANRRAFEERIEQAVRAHRRSGDQITLFYIDLDHFKAVNDSCGHAAGDKLLGELGVL
                     LKGRLRAEDEVFRIGGDEFAAILRGCGSEDARRIAEGLCTAIAAHAFECEGRTFRVGA
                     SIGVARMDPELQEVDALMIAADQACYAAKHGGRGHVVEYPLPAPAS"
     gene            complement(57559..57942)
                     /gene="apaG"
                     /locus_tag="P5537_02265"
     CDS             complement(57559..57942)
                     /gene="apaG"
                     /locus_tag="P5537_02265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011236625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Co2+/Mg2+ efflux protein ApaG"
                     /protein_id="HRV76898.1"
                     /translation="MSESTPYRVQVTAVAEYVAEQSRPQDDHFVFAYHITVLNTGSVR
                     SQLLARHWVITDGNGKMQEVHGQGVVGEQPVLGPGQAFRYTSGCVLATPVGTMQGSYR
                     MRADDGHEFEAEIPAFMLAVPKALH"
     gene            58024..59400
                     /gene="purB"
                     /locus_tag="P5537_02270"
     CDS             58024..59400
                     /gene="purB"
                     /locus_tag="P5537_02270"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0006188 - IMP biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HRV76899.1"
                     /translation="MSNAAPSPLTALSPLDGRYHGKVAGLREHFSEHGLIRNRVKVEV
                     EWLKALAAEPALAEIAPFSAATVAELDAVVANFSTEDGEAVKAIEATTNHDVKAMEYW
                     LKKRLGHNAEVMKVSEFIHFACTSEDINNTSHALMLAEGRDRVLLPALDAVIARFREL
                     AHALADLPMLSRTHGQPASPTTLGKEMANIAARLMRARAAIAGVAMCAKFNGAVGNYN
                     AHLSAWPAFDWEGFNRRFIESLGLTFNEYTIQIEPHDAMAELFDAVARANTMLIDACR
                     DIWMYISLGYFKQKLKEGEVGSSTMPHKVNPIDFENAEGNFGLANAVLKHFSEKLPIS
                     RMQRDLTDSTVLRNMGVGFGHTVLALDSCLRGLGKLEADPARLVADLDECWEVLAEPV
                     QTVMRRYGIENPYEQLKAMTRGKGITREALQEFIRTLAMPAEARDHLLAMTPASYVGK
                     AAELARRI"
     gene            59485..59802
                     /locus_tag="P5537_02275"
     CDS             59485..59802
                     /locus_tag="P5537_02275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002931470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2322 family protein"
                     /protein_id="HRV76900.1"
                     /translation="MAFADNLKTLPGVSHLAALNLIDAADTVVATIENKPGQAGSLAV
                     YNHLAQLYGAISPEAARKGLELYAEHTEDARTNPGKHPNIDRLIGLIERGETLRVKQV
                     FAI"
     gene            complement(60130..60897)
                     /locus_tag="P5537_02280"
     CDS             complement(60130..60897)
                     /locus_tag="P5537_02280"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF024880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HRV76901.1"
                     /translation="MQTASHNSVVLDQYATRASAYVNSAAHAAWQDLDLIAQLLANQR
                     GAVALDVGCGGGHLTYRLAPLVSQVVACDLAASMLAAVAEQASLRGLPNIATREAAAE
                     SLPFEVATFDVVATRFSAHHWHAFAEGIAEMARVLKPGGLALMSDVVSPGVSLLDTWL
                     QTLELLRDPSHVRDASTAEWDAALAAAGLAIERIEHLRLRLDFATWVARMDTPEPQVT
                     AIRMLQARAASAVKDYFEMEEDSSFTVDTALFVARKT"
     gene            60984..>61419
                     /locus_tag="P5537_02285"
     CDS             60984..>61419
                     /locus_tag="P5537_02285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019439189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HRV76902.1"
                     /translation="MNPSEARRLLGAFIRAHRERLSPPAKALGRRRTPGWRREELADA
                     AGLGVTWITWLEQGRAVNASVPALCRLAEALQLTPAERMSLFDLAGKRDPLASHAPTT
                     DLPAELLCLPGHVSAPAYLLDASYAAIAWNDQAGELFVGWLDT"
BASE COUNT         8873 a        21167 c        21820 g         9459 t
ORIGIN      
        1 tgtgatgcgc caggcaccac ttggccatga tcgagccgcc gcggctgacg atgccggtca
       61 tgcggttggc ggtcagcggc acgtagcgca gcagcacgcc ggcgtggatg gtgaagtagt
      121 ccacgccctg ctcggcctgt tcgatcaggg tgtcgcggaa gatctcccag gtgaggtcct
      181 cagccttgcc gttgaccttc tccagggcct ggtagatggg caccgtgccg atcggcaccg
      241 gcgagttgcg gatgatccac tcgcgggtct cgtggatgtt cttgccggtc gagagatcca
      301 tcaccgtgtc gccgccccag cggatcgacc aggtcatctt gtcgacctct tcggcgatgc
      361 tggaggtgac cgccgagttg ccgatgttgg cgttgatctt ggtgaggaag ttgcggccga
      421 tgatcatcgg ctcgctctcg gggtggttga tgttgttcgg gatgatggcg cggccgcggg
      481 cgatctcgtc gcgcacgaac tcgggggtga tcgtcgccgg caggctggcg ccgaagttct
      541 ggcccgggtg ctggcgcagc atcatgtcgg ccatcttctg gcccttgagg ccgccgctgg
      601 cgcgcagcga ggcgatgtac tgctcgcggt tgagattctc gcggatggcg acgtattcca
      661 tctcgggggt gatgatgccg cggcgggcat agtgcatctg cgtgacattg gcgcctgcct
      721 tggcgcggcg cggcttgcgg tgcaggccgg ggaagcgcag ctcgtccagg ctctcgtcgg
      781 cggcgcgctg gcggccgaat tcggacgaaa gatcgggcag cagctcggtg tcggcgcgct
      841 cctcgatcca ctgctggcgc agcgcgggca ggccggagcg gatgtcgatc ttcgccgccg
      901 ggtcggagta ggggcccgaa cagtcgtaga cgaagatcgg cgggttctgc tcggcgccga
      961 aggaggccgg ggtgtcggcc tgcgagatct cgcgcatcgg cacgcggatg tccgggcgcg
     1021 agccctcgac gtagatcttg cgcgagttgg gcagcggggc gatcgcggcc tcgtcgacgt
     1081 gggccttggc ggcgatgaat ttttcgttgg cgttcatgct gtctcctggg gaagttcgtg
     1141 gtgtttgtgg ttcagttcgg ggtcgcgcca gccgcctttc cgcgaccaat gcgagcattc
     1201 acatgtagga gcggcggcag ccgcgaaccc cggcccgtga cccccgccct gcctcggccc
     1261 gagctcaccg cttccacagc gcgtggaagt gatgcaccgg cccgtgcccg ctgccgaccg
     1321 cgagctcgcc cgagtgcacg atcgcgccca gcagccactg gcgcgcatgg cgcaccgcgg
     1381 tctcgaccgg gcggaactgg ccttcggcct gcggcagcag cgcggcgatg gccgagctga
     1441 gcgtgcaccc ggtgccgtgg gtgtttttgg tgtcgatgcg ctgcgccggc agctcgacca
     1501 tgcggtcgcc gtcgaacagc aggtctacga ggtcgttgcc gggcaggtgg ccgcccttca
     1561 gcagcaccca gcgctcggag gccagcggca gcagctcgcg caggcgttcg gcggcgcggt
     1621 acatctcctt gaccgtgtcg ggcgcgcgct gctcgagcag cacgccggcc tcgggcaggt
     1681 tgggggtgat caggaaggcc tgcgggaaca gcgcctcgcg catcgccgag atcgcgctct
     1741 tcgccagcag gctgtcgccg ctcttggcca ccatgaccgg gtcgagcacc acattcgccg
     1801 cccgccagtg cgccaggcgc tcggccaccg tggtggtgac ctcggcgctg ccgagcatgc
     1861 cgatcttggt ggcgtggatg gagacgtcgg cgaacagggt gtcgatctgc aggcgcagga
     1921 agtcggtggg cggcacatgc acgccggtga ccgcctgcgt gttctgcgcg gtgagcgcgg
     1981 cgaccacgcc gcagccgtag gcgccgagcg cggaaaaggc cttgaggtcg gcgaacacgc
     2041 cggcgccacc ggacgggtcg acgccggcga tggtgaccac gttggggatg tgggaggacg
     2101 tcccggaaga gcgggacgag gcgctgccgg aggcagcgga gcttgcggac gaactcatga
     2161 aggacgtttc cctacgccgg tgcgagccgg atcaggttcc aagggtgttt ctcagcccgt
     2221 gcgcggcggg cacccccaac gagagcgaag gaagatactg tatgcacttt agcgtggcaa
     2281 gccgctcaag atcccgccct cgtggtcgtt tagcaggatg gaacgccacg ccatgccgac
     2341 gccgatgaaa aacccgcgcc ctctcctcct cgccctgctg ctcgcccact tcgccggcgc
     2401 ggcctgcgcc gccgactggc agctcgtgct cagcgaccgc gaccgccgca tcgagatcga
     2461 tcgcgccagc atcctgcgct cggacgctgg caccaaggtc tcctgggggc gggtggtgct
     2521 gacctcggag gaggcgcagc gctccggcta cgccatgatc aaggcgctca accgttacga
     2581 ctgccgcaac cgcacgttcg ccacggtcaa gcgggtatat gtcgatgccg aggacaacat
     2641 cgtgcgcgag gagccggtgt cggccgaggc gccgatcgcg gtggcgcgca acaccgtgga
     2701 tgagcgcatg tggcgcgagg tgtgcgatcc gccctcggcg gtcgagctgc agaagctggc
     2761 ggccgaggcc gcccgggtcg cgagcgaaca gccggcagct ccaggcgtcg cgccacccca
     2821 ggcctccgct gccgcaaccc ccgctgccgt cccccccgcg gtgccggtcc aggtccccgc
     2881 cgcggctgcg cagccgccgg tgccgaagcc tgcggagtcg gcgcgcgcgc agtcgggcag
     2941 cgtacgccag ccgggcgagg agtccgtctc cgccgaggtg gtgcgtacgg cgggcggagg
     3001 tggcgagcct gccgcggcga cccccgccct cgagacccac gtcgagattc cggccaagtt
     3061 cctgcccggc gggcaggggg ccgcggagcc cgagagtccg cgcaagtcca tcctgccgcc
     3121 gctgcccagg ctgtcggcga cggccgcgcc cgaaccgaag gctccgccgg ccaccaagcc
     3181 tgccgtgcgc gagtcgccac gagcgcaggc gggcggcccg cccgctccgc aagcgcccgc
     3241 gccgacgcga tcggcagcgg cgccggagcg gcgggtcgtg ccggaggcgg agaaaacgcc
     3301 tgcgtcggtg cgggccgagg tgtcgcccgc gcgtgctcgg ccccgtccgc agcgcgcgga
     3361 gagtgcgccg ccggagcgtc ccgtcgtgcg cgagaagccg ctcgtggcca gggccgagcc
     3421 tgccacgccg gcacgaccga cgtcgcccgg cgcgcgcgcc ctcgcgccga agcgcgccgc
     3481 ggtggcggag ccatcggatt cgccggccgc gacgcctgcg tccgcccgcg cggaggcctt
     3541 gcgcgcggcc ggcatcgagc tcacccgcct cgccgtgggc atgcccgagt ggagctacga
     3601 gggcgagacc ggtccggaca actggggccg gatgcgtccc gagtggcgga tctgcgagga
     3661 gggtttgcgc cagtcgccga tcgatttgcg cgatggcatc gccgtcgatc tcgccccggt
     3721 gcagttcgac taccgtcgca cgggcttccg catccgcgac accggcaaca ccctgcaggt
     3781 cgaggtcggc gagggcatgg gcatcaccgt gcgcggggtg cgctacgcgc tcgagcgctt
     3841 caccctgcac cggccctcgc aggaccgcgt cggcggcatg gcgcacgaca tggcgctcta
     3901 cctgcagcat cgcgccgagg acggccgcat ggcgatcctg tcgctgctgc tgtcggccgg
     3961 cggcgaggcc aacccggcgc tgcagacact gtggaacaac ctgccgctcg accgcgggcg
     4021 cgagttcacc cccgacgccg tgctcgacct gccggcgctg ctgccggccg agccggggca
     4081 ttacctctac accggctcgc tgccgatgcc gccctgcacc gaggacgtgc tgtgggtggt
     4141 gatgaagcag ccggtggcca tctccgccga ccagctcgac gtcttcgccc gcctgtatcc
     4201 gcgcaacggt cggccgatcc agccgaccaa cgggcggccg ctgctcgagt cgcgctgagc
     4261 tcccggcctt gcatcaggcc gcgctcgtct gcggatcggg cgcgggccgt gcgcagggtc
     4321 atcgcacgaa cgggcacccc gcctcgagcc acgctttcac ggcgttctcg tgcgaccgcc
     4381 ccggggctgt gcctgggtga ccatggtcac acgggcgagg cgctacacta gcggcctcgc
     4441 cccgcgtctg cgccttgtcg ccaggggcgc tcccgatcgc cgcgagattt ccatgcgttt
     4501 ccgctccctc ccctccgtgc tggccggcct gtccgtgctg gccgcctgtt ccgcgcccgc
     4561 gccccacacc ccgccgccgc ctgcggtcct cgtccgcagt gttgacgctg ccagcgcccc
     4621 gccggcggcg caggtctatg ccggcgaggt gagggcgcgc atcgagtcgg atctgggttt
     4681 ccgcatcggc ggcaagctgg tcgagcgcct cgtcgatgtc ggtgccgagg ttgccgccgg
     4741 tgcgccgctg gcgctgctcg acgcgcagga cgtgcgcctg gcgctggcct cggcgcaggc
     4801 ggcggccgcg gcggccgagt ccgacctcgc gctcgcacgc agcgagttcg cccgcgcgcg
     4861 cgagttgcag gcgcgcaact tcatctcgtc ttcgtcgctc gacgcccgcc gcaccgcgct
     4921 gcaggccgcc gaggcgcgcc tgcgccaggc gcgtgcgcag gccgaggtcg ccgccaacca
     4981 ggccggctac gcccgcctcg aggcacccgc cgccggcgtg gtcaccgcgg tgctcgccga
     5041 gccggggcag gtggtggggg cgggccaggc ggtgctgcgc ctcgctcgtc ccgacgagcg
     5101 cgaggtactg atccacgtgc ccgaggggcg cgccgccggc ctcgtgccgg gcagtgccgc
     5161 gcaggtgcgg ccgtgggccg cgcccgaacg cgagtacgcc ggccgcgtgc gcgaggtcgc
     5221 accggcggcc gacgccgcca cccgcaccca cgcggtgcgt gtcgcggtgc ccggggcgga
     5281 cacggcgctc gcgctcggcg ccagcgcgag cgtggccttc gccgcggcgc aggccgaggc
     5341 ccccggcgtg ctgttgccct tgcccgcggt gacgcggcag ccgggccagg ccgacgccgg
     5401 cacggtgtgg gtggtgggcg aggacgccgc cgtgaagccg ctggcggtcg aactcggcgc
     5461 ctggcgcgag gacggcgtgg tggtgcgcgc cggcctgccc gcacaggccc gcgtggtggt
     5521 ggccggggtg cacaagctga tcgagggcat gcgcgtgcgt gccgtcgagg aaggcgcgcc
     5581 ggtgctgctg gacgtgcggc gatgagcgct cgtggcgagg gaccgatcgg cggcgggcgt
     5641 ttcaatctgt cggaatgggg gctgacccac cgctccctgg tgctgtactt cctcatcgtc
     5701 tgcaccttga tcgggctgtt ctcctacacc cggctcggcc agtccgagga tccgcccttc
     5761 accttcaagg tcatggtggt gcgcgccgag tggccggggg cgagcgcacg cgagatcggg
     5821 gagcaggtca ccgacaagat cgagaagaag ctgcaggaga tcgcccaggc cgacgtcatc
     5881 cgcagctact ccaagcccgg cgaggcgatg gtcttcttcg tcgtcaagga cgctacgcgc
     5941 tcgcgcgaca tccccgacat ctggtaccag gcgcgcaaga agatcggcga catcgcccac
     6001 accttcccga ccggggtgcg cgggccgtat ttcaacgacg agttcggcga cacctacggc
     6061 aacctcttcg ccctgctcgg cgagggggtg agccacgccg aactcaagcg ccacgccgag
     6121 gcgatccgcg gcgaactgct gcgcgtgaag gacgtggcca aggtgagctt cttcgccgag
     6181 cagccgcagc gcgtgttcgt ggagatctcc aacacccgtc tcgccaccct gggcgtgcgc
     6241 ctggacgaca tcgtcgccgc gctcgcccgc cagaacgcgg agaccggcgc cggcttcttc
     6301 gagaccggcg acgagcgcat ctggctgcgc ccgtcgggcc agttcgagga cctcgacgcg
     6361 atccgtgcca cggtgatccg cgccggcggg cgcagcctgc gcctgggcga catcgccgag
     6421 gtgcgccgcg gctacgccga gccaccggcc gagcgcctgc gctacatggg gcaggaggcg
     6481 ctcggtatcg gcgtgtcgat gcgcagcggc ggcgacatcg tcgcgctcgg ccgccagctc
     6541 gatgcggcgg tggagaagat cgacgcgcaa ctgccgaccg gcattcgcct ggagcgcgtg
     6601 gccgaccagc cgcgcgccgt gacgcgggcg gtcaacgagt tcgtcaaggt gctcgccgag
     6661 gcggtgctca tcgtcatggc ggtgagcctg ctgtcgctgg gcttccgcac cggcgtggtg
     6721 gtgctggtga tcatcccggt ggtgctggcg atcaccttca tgttcatgca cctgctcgac
     6781 atcggcctgc acaagatctc gctcggcgcg ctgatcatcg cgctcggcct gctggtggac
     6841 gacgcgatca tcgcggtcga gatgatggcg agcaagatgg agcagggctg gggtcgggtg
     6901 cgcgcggcga gctacgcgtg gacctcgacg gcgatgccga tgctctcggg caccctggtg
     6961 accgcggccg gcttcctacc ggtggcgctg gcggcgtcct cggtggggga gttcacgcgc
     7021 tcgatcttcc aggtcacggt gaccgcgctg ctggtgtcgt ggatcgccgc ggtgctcttc
     7081 gttccctacc tcggctatta cctgctgccc gacttcagca agcgcgcggg caagccctcc
     7141 tggctggccc gcctggtcgg gcggatctgg ccggcgctgg ggcggcggat ggcggagcgc
     7201 gacctccacg cccacgagca gcacgacgag ttcgcgatct accacacgcc cttctacaac
     7261 cgcctgcgcg gcgtggtgga tgcctgcgtg cgctggcgct gggtcgtcat cgtgctgacg
     7321 gcagccatct tcgtcggctc gctgttcgtg ttcgcccgct tcgtgccgca gcagttcttc
     7381 cccgactcga cgcgccccga gctgctggtc gacctgcgcc tcgccgaggg cgtgtcgcac
     7441 cacgccaccg aggccgcggt gaagcggctg gagggcttcc tcgacgcgca ggagggcatc
     7501 gagaactacg tggcctgggt gggcagcggc agcccgcgct tctacctgcc gctcgaccag
     7561 cagctcgcgc agaccaactt cgcccaggtc gtgatcctca ccgccggcct ggccgagcgc
     7621 gaggcgctgc gcgcgaagct gatccgcctc ttcgaggacg agccctggcc gctgcgcggc
     7681 atcgtcaatc ggctcgagaa cgggccaccg gtcggctttc cggtgcaata ccgggtgagc
     7741 gggccggacc tggcggagct gcaccggcgc gccgcgaccg tggccgagac gatgcgtgcc
     7801 aatccgcacc tgtccaacgt gcatatggac tgggtggagc cgtccaaggt ggtgcgggtg
     7861 gtgatcgacc aggagaaggc gcgcctgctc ggggtgtcta cacaggacct ctccagcctg
     7921 ctcgccacct cgctgcaggg catgacggtg acgcagttcc gcgagggcac cgagaccatc
     7981 gcgctggtgc tgcgcggggc ggagcgcgag cgtgcccacc tgtcgcagct gcccgacctc
     8041 gccctgccgg tggggggagg gcgcagcgtg ccgctggcgc aggtggtgcg cctcgagcac
     8101 gacttcgagc cgggggtgat ctggcggcgc aaccgcatcc ccacggtgac cgtgcgcgcc
     8161 tcgctctacg acggcaccca gcccgcggtg gtggtgggcc agctcgcgcc gcgcatggcc
     8221 gagctctccg cgcagctgcc gctcggctat cgcctcgagg tcggcggcgc ggtcgaggag
     8281 agcgccaagg gcagcggctc ggtgggtgcg ggcatgccgg tcttcgtgct gaccgtgctg
     8341 accgtgctga tgctgcagct gaagagcttc tcgcgcacca tcatggtggt gctcaccgcg
     8401 ccgctcggcc tcatcggcgt cgccgccttc ctgctcgcct tcggcaagcc cttcggcttc
     8461 gtcgcgctgc tcggcacgat cgcgctgtcg ggcatgatca tgcgcaactc ggtgatcctg
     8521 gtggaccaga ttcgccagga cgtcgaggcc ggacgcacgc agtgggaggc tatcgtcgag
     8581 tcggcggtgc ggcgtttccg cccgatcatg ctcaccgccg cggcggccat cctcgccatg
     8641 gtgccgctgt ctcgcagcac cttcttcggg ccgatggcgg tggcgatcat gggcgggctc
     8701 gccgtggcca cggtgctcac catcctgttt ctgcccgcac tctatgcagc ctggtaccgg
     8761 gtgaagccgg ccgcagcgga gcgcgcggag cgcgcggagg cggatcgcag cgcagcaact
     8821 gcgctagaat gacgcggttt tgccttcatg gataacgcta tccattagcg tgtgctaata
     8881 tttcgccggg agcccctgat gaacttcgag aaagcgcgct tcaacatggt cgagcagcag
     8941 atccgcccct gggaggtgct ggatcaggac gtgctcgacc tcctgatgac ggtcaagcgc
     9001 gaggaattcg ttcccgccgc gcaccgcgag ctggccttcg ccgacgtcga gatcccgatc
     9061 ggctgcggcc aggtcatgct caagccggtg atcgagggca agatcctgca ggcgctgcgc
     9121 gtcaccaagt ccgacaccgt gctcgagatc ggcgccggct cgggctggtt cgccgcactg
     9181 ctggcggcgc gcgccgagtg ggtgcgcacc atggagatcg agcccgaact ggtcaagctg
     9241 gcgagcgcca acctcgagcg caacggcgtg caaaacgtgg tcgtggtcga cggcgatggc
     9301 gtgcagggct ggtcgggccg cgcgccctac gatgtgatcg tcgtctccgg cggcctgccc
     9361 ttcgtgccgc agtcgctgct cgagcagctc aaggtcggtg gccgcctgtt cgccttcgtc
     9421 ggcgaggcgc cggtcatgaa ggcgcgcctg atcacctgcg aggcagaagg ccgattccgc
     9481 acagaggacg tgttcgagac cgtggtgccg atgctcaaga acgcccccca gcgcgaagcg
     9541 ttcagcttct gaggcgacga tgctgcagat cacgccgaag atgctcgccg agcgcctcca
     9601 ggacgcgcaa cggcctgccc ccctgctgct cgacgtgcgc gagccctggg aggtgcagat
     9661 ctgccagatc cccggatcgg tcacgatgcc gatgggcagc gttccggcgc gttacccgga
     9721 actggaacgc gaccgcgaga cggtggtgat ctgccatcac ggcgggcgca gctggcaggt
     9781 cgcgatgttc ctcgagcggc agggtttctc caacgtggcc aacctgtccg gcggcgtcgc
     9841 cggctgggcg aacgaggtcg acctcaacat gccgcagtac tgaacgcggc gcagcagtgg
     9901 agagcacgat gaagcgagtc ctggcagttc tggtggcggg tctgttcgcg ggaggcgccg
     9961 cgggggccga cctgatgcag gtgtaccagg acgcgctcgc caacgatgcg aagttctccg
    10021 cggcgcgcgc gcagttcgag gccgggcagg agaaggtggt tcaggggcgc gcggggctgc
    10081 tgccgcagat cggggtgtcg gcgaacacga cccgtaacga tgccgagctc acaccgacgg
    10141 gagcggctgc gcgcgactac agctacagca gcaacggcta tggcgtgcag ctcacccagc
    10201 cgctgttccg ctggcagaac tgggtgcagt tcaagcaggg cgagctgcag accgcgctcg
    10261 cggaaaccca gttcgggatc gcccgccagg acctcgtgct gcgcgtcgcc gaggcctact
    10321 tcaacgtgct caacgcgcag gatgcgctcg ccgcggtgac gcagctgcgc accgccgcgg
    10381 gcgagcagct cgagctcgcg aagaccagct tcgaggtcgg cacggtgacg atcaccgacg
    10441 tgcatgaggc gcagtcgcgc ttcgacctcg cctcggcgca ggagatcgcc gcacagaacc
    10501 agctcgaggt tgcccgccag acattggcgc agatcatcgg caggcagccc gaggcgctcg
    10561 ctggcctgcg cgagggcgtg gcgctgcagc gcccccagcc cgagaacatc gccgactggg
    10621 tggccgccgc cgagtctggc agcttcggcg tgcaggccca gcagctcgcg cgcgagatcg
    10681 ccgcgcgcga ggtcgagcgc gcgcgcgccg gccacctgcc gacggtggat atcgtcgcca
    10741 gccacggcct gaacaaccgt ccgcagccca gcaccgagcg ctccgaggcg accaccatcg
    10801 gcctgcagtt gaacgtgccc ttgtatgccg gcgggcgcgt gtcctcggtg tcgcgcgagg
    10861 ccgcggcgct gcgcctgaag gccgacgccg acctcgagga cgcccgccgc agcgccgcgc
    10921 tcgccgcccg ccagtcctgg ctgggggtta ccagcggcat ggcgcaggtg agggcgctcg
    10981 aggctgcgcg cgtgtcgtcg agctccgcgc tcgacgccaa caagctcggc tacgaggtcg
    11041 gcgtgcgtat caacatcgac gtgttgaacg cccagaccca actcgccgac accttgcaga
    11101 agctcgcccg tgcgcgctac gacaccctgc ttgcgcagct gcgcctgaag gccgcagccg
    11161 gcaccctggg cgaggacgac gtgctcgcga tcaacgcgct gctcgtgccc tgagcgcctc
    11221 gggccgatca cactccctgc gcctcacgcc tcacgcctca cgcctcacgc ctcacgcctc
    11281 acgcctcacg cctcnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnctcacg
    11401 cctcacgcct cacgcctcac gcctcacgcc tcacgcctca cgcctcacgg ccagcgccct
    11461 gagcagcgcc acgctgcgcg cggtcgcacc ctggtgcgtg gtcgcgaagg cgcgccccgc
    11521 ggccgcgatc tcgtcccggc gcgcggggtc tgccaccagt gcgagcgcca cgcgcatgcc
    11581 cgcctccgca tcctgcgcgc gcactgcggc gccggcgcgc tcggcgtcct cggccaccgc
    11641 ctggaaattg aaggtgtgcg ggccgatcac caccgcggtg ccgaccgcgc aggcctcgat
    11701 caggttctgc ccgccgaagg ccagccagct gccgccgatg agcgcgacgt cggccgcggc
    11761 gtagtaggcg aacatctcgc ccatcgaatc accgagcagt acgcgggtct gtgcgcgcac
    11821 cgcctcttcg gtgctgcgcc gctgcagagc caggccgcgc gcgctggcga gcgcggcgac
    11881 ttcgtcgaag cgctgcgggt ggcgcggcac cagcagcagc aaggcctcgg gtgtcgcctg
    11941 gcgcacgaag gcgtcgagca gcagtgcctc ctcgccctcg cgggtgctgg cggcgagcag
    12001 caccggacgg ttgccgatgc gttcgcgcag gctgcggccg agtacgagca tcgcccctgg
    12061 tggggcgatg tcgaacttga ggttgccggt gacggtgacc cggcgcgcac cgagctgggt
    12121 gaggcgggag gcgtcggcgg cggtctgcgc gccgatggcg gcgagcgcct tcagggtgag
    12181 cgcggtgagc gcgggcaggc gggcgtagcg ccgggcggag cgctcggaca ggcgggcgtt
    12241 ggcgagcatc accgggacgc ggcggcgttt gcaggccgcg agcaggttgg gccatagctc
    12301 ggtctccatc accactccga acaaggggcg gaagtggcgc aggaaggcat gggcgaagca
    12361 gccgaggtcg tagggcaggt aggcgcggag gacgcgcgcc tcgtcgcgga aaagggcctt
    12421 cgaggtctcg cgcccggtcg gcgtcatgtg ggtgagcagc accgagtgct ccggccattc
    12481 ggcgagcagg gcgcgcacca ggggttcggc ggcgcgggtc tcgcccacgg acactgcatg
    12541 cacccagatc actcccaccg gtgcccgcgt ccggtagcgt ccgaagcgtt cgccaaggtg
    12601 gcgcaggtag gccggctggc gccgggcccg ccacgcaagg cgcagcagca ccaggggcag
    12661 ggcaaggatc cacagcaagg tgtagggcag gcgggtcagc atcgggtggg acggtaaggc
    12721 gaccgccgca gtataagcaa ggatgctggc ggcggtcctg cgcacgtgct gaaggaaacc
    12781 gttcacactg tgtcccggcg ggggcatgcg ataattcgtc caatccatcc cccagcccaa
    12841 gttcctccat gaagatcctc gtcaccggcg ccgccgggtt catcggcatg cacgccacgc
    12901 tacgcctgct cgcgcgtggc gacgaggtgg tcggcctcga caacctcaac gactattacg
    12961 atcccacgct caaggaggcg cggctggcgc ggctgctgcc gcacgcgggt ttccgcttcg
    13021 tgaagctgga cgtggcggac cgcgccggca tcgaagcctt gttcgccgcc gagaagttcg
    13081 accgcgtgat ccatctggcc gcccaggccg gcgtgcgcta ttcgttgcag aacccgcatg
    13141 cctacgtcga cagcaacctg gtcggcttca tgaacatcct cgagggctgc cggcatgcga
    13201 aggtgcagca cctggtctat gcgtcgagtt ccagcgttta cggtggcaac acgaagatgc
    13261 cgttctccga ggccgacagc gtcgaccacc cggtgagcat ctatgcggcg accaagaagg
    13321 ccaacgagct gatggcgcat acctacagcc acctttatgg cctgcccacc accggcttgc
    13381 gcttcttcac cgtgtatggt ccgtgggggc ggccggacat ggcgctgttc ctgtttacca
    13441 aggcgatcct ggaagggcgc ccgatcgatg tgttcaacca cggtcgcatg cggcgcgact
    13501 tcacgtacgt ggacgacatc gtcgagggcg tgatccgcac cctggaccgc gtcgccgagc
    13561 ccgatcccgc cttcgatccg atgcagccga acccgggtac cggcagcgcg ccctaccgcg
    13621 tgttcaacat cggcaaccac gatcccgtag agctgatgga gttcgtcgcc gcgatcgaga
    13681 atgcgctggg caccaccgcg cagaagaact tcctgccgct gcaggacggc gacgtgccgg
    13741 cgacctacgc cgacaccgcg gcgctgaacg cctggaccgg cttcgctccc gcgaccagcg
    13801 tgcgcgaggg cgtcggccgc ttcatcgcct ggtaccggga gtactaccgg gtctgatccg
    13861 cccgggggcg gcccggcgcc gcggccgctc ccgatcttca actgtccatg cgctgccggc
    13921 tgtcggccgg cagcggcagg aatcgatggc cacctacgca atcggcgaca tccagggctg
    13981 ctatgccccg ctggaccgca tgctcgagct gatcgccttc gacgcggccg tcgaccggct
    14041 gtggatcgtc ggcgacctcg tcaatcgcgg cccagaatcc ttgcgcgtgc tgcgcttcct
    14101 gcgcgggctg ggcgacgcgg cgagcatcgt gctcggcaac cacgacctct acctgctgat
    14161 ggtcgccgcc ggctacaagc ggcgcgacag cgacgacacc ctcttccagg tgctcgaggc
    14221 ggacgaccgc gacgagctgc tggagtggct gagcttccag cccctgatga gggtccaggg
    14281 cgaccacgtg ctggtgcatg cgggcctcct cccggggtgg acggtgacgc gtgcgcaggc
    14341 gctcgccgcc gaggtgggtg cggcgctcgc cggcccgaag tcgcgcgagt tcctgctcca
    14401 cctcgcgggc aaccgtccgg atcgctggtc ggacgggctc aagggctggg accggctgcg
    14461 cgtcatcgtc aacgccatga cgcggctgcg cttctgcacc gcgcaggggc gcatggacct
    14521 gggcgccaag ggtgcgccgc acaaggcacc gccgggcatg ctgccgtggt ttcgcgtgcc
    14581 cgatcgcttc agtcgcaccc acaccatcgt ctgcgggcac tggtcggcgc tgggcttcta
    14641 ccgcgagccg gggttgatcg cgctcgattc gggctgcgtc tggggcggaa agctcaccgc
    14701 gctgcgcatc gaggacgatg cggtgttcca ggtcccgggc tgagcctgcg ccggtggttt
    14761 cagtcctgcg cgtcgagcgt gatgccgatt acggtggcga tctcggcgcg cgtgcgcgta
    14821 gccagcgtgc gccggtcggc gccgtcggcg gtggtgatcg gtgccgccac cgtgatgcgt
    14881 gcgaccgtgc gtggcgcggc gatgatgttg gcgatgcact cgcccaggct gagctcgccg
    14941 tcgtaggcgg gcgtgcggct gaagcggtcg tccggcgtcc ggtattgcag tgccagtggc
    15001 tgcaccggat gaccgcaggc gatcgccggc tgcagcagcg cggcgtgaaa gtgcagcaag
    15061 gcggcgccgt cggtggtcgt gccctcgggg aagatcgcca cgttgcagcc tgcatcgagc
    15121 agcgccgcgg tctcctcgtt gatgatgcgg gcgtggccgc ggctgccgcg gcgcaggaag
    15181 atggtgtcgt tcttcgccgc cagccagccg atcaccggcc aggcgcgcac ctcggccttg
    15241 gagacgaagg ctgcgggggc gagcgcgttg atcgcgaaga tgtctaccca ggagacgtgg
    15301 ttggcgacca gcatgcagcc gggcgcgacc gcctcgccgc gatgttccag gcgcatgccg
    15361 agcacgcgca gcagccccag cgaccagcgt cgacgcaggg cctgatgagt gtcgcgcccg
    15421 gtgaaggggt agaccgccgc gatcgtcagc acgccctgca gcagatgcag gccgagccgg
    15481 gtccagcgcg tcgcgcgcag catcgcgccg gcgcgcgctg cgcccacccc ggcctcgacg
    15541 gcgggcgtgg tggtcgagga gggcggcggg gcggtgtcgg caccggcatg catggcgcga
    15601 tcctgggcga ggtcggggtg gcggggggcg ttcagtcctt gcgtcccatg aagtggcggg
    15661 cgtagcggtc gtccacccgg ccgatcggca tcaggatggg caggtccgcg gtgttgaagt
    15721 cggggtccca tgccggctcg ccgcagatcc acgcgcccgc gcgcaggtag cccttgacca
    15781 gcggcggcgc ctcggcgtcg aggtcgccgc gcaggctggc gagcggcagc gggcagcgcg
    15841 ggaagacgtg gtactcgagc ggggcgaggt gtttttcgcg cagccgatta tacaggctcg
    15901 ccgcgacgtg cccgccgtcg gccatgctca ccgaggcgca gccgatcagg tattcgtagc
    15961 cgttctcctg catgtagcgc gcgagccccg accacagcag cgcgatcacc gcgccgctgc
    16021 ggtagtcggc gtcgatgcac gagcgcccga tctccaccag ctggccgcgc aggtgctgca
    16081 ggcgggtgag gtcgaactcg ttctcggagt agtagccgcc cacccggcgc gcggccgagg
    16141 gcgacaggat gcgataggtg ccgacgatgc ggccggcgtc ctcgtcgcgc acgatcaggt
    16201 gctcgcagaa ggggtcgtag aggtcgcggt ctacgcccgg gctgcgcgtg ggcaggcggg
    16261 cgcccatctc gtcggcgaag acccggtagc gcagcttctg cgcctcgagg atctcggtct
    16321 cgctgctggc gaggccgacg tgcaggttgc gcgtcttgcg cgcggtggtt tgctggcggg
    16381 gctggaggtg ctggagcatg gcctgtttcc gtcctgttgg gtgcggacca ttctcgaaac
    16441 ccggcgttgc gacgcggtga cgtgctggtt acgatgcgat gacgccaccc tggcccaagg
    16501 aggaccccgc atgccgccca cgaccccgcc tgatcacgac ccgaattgcg tgttctgccg
    16561 catcgcgcgc ggcgaactgc cgtcctcgaa ggtgtatgag gatgcggaca cgctcgcgat
    16621 catggacatc cagtcggtca atcccggcca catgctggtg ctggtcaagc cgcaccgcgc
    16681 caacgtctac gcgctcgacg acgccctcgc cggcgcggtc ttccgcaccg cggcgcggat
    16741 ggcgcgcgtg gcgaagaagg cgacaggctg ccagggggtg acgctgctgc aggccaacga
    16801 gaaggccggc gcgcagaccg tgttccactt ccacattcac gtgctgccgc gctgggaggg
    16861 cgacggcatg gagctggcct ggccggtcaa gaacccgccg cgcgaggcgc tcgaggagat
    16921 ggcggcgaag ctgcgcgagg cgctcgccgg cgaggtgtga ccagccggga ggtgccgggg
    16981 agggggggcg gagggggcgc gtataatccg gcttccgctc acccaccgcc tatctgtctc
    17041 ccatgtccat cctcgtctgc ggatcggtcg cctacgactc gatcatggtc ttccacgacc
    17101 gcttcaagaa ccacatcctc cccgagcaga tccacatcct caacgtctcc ttcctggtgc
    17161 ccgacctgcg ccgggagttc ggtggctgcg ccggcaacat cgcctacggg ctcaagctgc
    17221 tcggcagcga cccgctgatc gtcgctaccg tcggcgagga cgccggcccc tatcgcgcgc
    17281 gcctgcgcac gctcgggctg cgcgaggact tcgtgcgcga ggtgccgggc agcttcaccg
    17341 cgcaggcctt catcaccacc gacctcgacg acaaccagat caccgccttc catccgggag
    17401 cgatgttcca ttcgcacctg aacgacgtgc gctccgcgac cgatgcgacg ctgggcatcg
    17461 tctcgcccga cggcgccgac ggaatgctgc gccacgccga cggcttcgcc gcctgcggcg
    17521 tgcccttcgt gttcgatccg ggccaggcgc tgcccatcct cggtagcgaa gcgttactga
    17581 aatgcctgca acaggcgcgc tactgtacgg tcaatgacta cgaggcccgg ctgatgtgcg
    17641 agaagaccgg gcgcaacgaa gccgaactcg cgcgcgaggt cgaggcgctg gtggtgacgc
    17701 tgggcgccga gggttcgcgc gtgcactggc gcggcgaggt gttcgaggtg ccggcggtga
    17761 aggcggatgc gatcgtcgac ccgaccggct gcggtgatgc ctaccgcgcc ggcctgctgc
    17821 acggcatcgc cgcgggctgg gatctgccga ggagtgcacg cctggccgcg gtcatggggg
    17881 cgctcaagat cgccgagcgt ggtggacaga actacaagcc ctcgcgtgcg gacattgcgt
    17941 cgcgctaccg cggggctttc ggagagaatc catggtgaat cgaagcagga tgaagtggcg
    18001 cgccttggcc ggcgcggcga tcgcggtgct ggtccttggc ggatgcgcgc agggactggg
    18061 cggcggcacc tattcgcgca ccgaggcgcg gcgcgcgatg acggtgcagt tcggcaccgt
    18121 cgagtcggtg cgcgcggtgc agctcgaagg cacgaagacg ccggtcggct cggttgcggg
    18181 tgcggccatc ggcggcatcg cgggcaatac ggtcgggggc ggacgcgggc aggcgatcgc
    18241 gaccgtgatc ggtgcggtgg ccggcgggct cgccggctcg gcggtggagg agggtgcgac
    18301 ccggcaaccg ggagtcgagg tcaccgtgcg cctcgacaac ggccagttcc ttgccgtcgt
    18361 gcaggccgac gagggcgaac gcttccgcct cggcgagcgc gttcgcatcc tgcgcgacgc
    18421 cggcaccacc cgcgtctcgc gctgaacttc cgccttccgg ctgacgccta aagcctcacg
    18481 gataaaacgc ataaatccga taccctgtcg gcgccagcgc cggtgcggca aaggggatgc
    18541 gcaattcgat cgcgctgcgc gcagtgaagg cttcgcgcgg ctgcgtcggc ggcagccagt
    18601 ccgagggcgg caggacgcgg cgcgagatcg ggttgtcgcc ggcgtcggtg agggtgagtt
    18661 ccaaatgcgg ccactgctgc ggatagtccc cgcggttgtt gagcgtggcc tgcagcaggt
    18721 agtacccggg gcgcccgggc tcggcctgca ggtcggaggc ctcgatcgcg atgtgctccg
    18781 cgtcgcgcgg atacggcacg ctgcagccca ggcgcgcgca agcctcgctc aggatgggac
    18841 gcaggccggg cagcgcacgg gcgatctcca tgcgatacag ataagtggcc tgggctgcga
    18901 gcagcgcgga caagccgacc gtgagcagcc acgcgagcgc gcggaagagc ggatggattt
    18961 ccttgcgcgg ccgcccgtag ttggcgtcga gacgggcgag gtcgggctcg ggagcaaagg
    19021 gcgccacttc ctcctcgtgc gcggggacgg gctccggctc gggatgtctg ggctcggggg
    19081 gcgattcggc gagcccgggg atctcggtgg ccggctcgtc gtcgaagtgt ggcggtggcg
    19141 cataggagat cgtcggcgcg aaggcggtgt cttccgcgac ggtcatgccg cggccatggg
    19201 ggcggccttc gtcgtcgcgg ctggatgggc cccggcgggc gctgcgcagg acctcgggaa
    19261 acggcggggg cgatgcggtg gactcgtcgg gggaaaggcc cacgtcggcc ccggcgccat
    19321 cctctgcggg cgcgggcgat gtcacggacc tgggcggtgg cgccagccaa tcctcgtaat
    19381 cgtccaggtc gggctgcggc gcacggatgg gcggcgacgg cgcgacctcc gggatgtcga
    19441 agtcgagaag cggatctggg cgtgtttcgc gcaccggcct tgccgcaggg ggcggggggg
    19501 gcggtgcggt tgcggtcacg tcgtcacgaa cctcgaccgt gttctcgagc gcgttgaagg
    19561 ggtggaagca atgcccgcag cggacctcgc cgccccgtgc gtgaagctgc tccgggcgca
    19621 gccggaacac cgtctggcag gcggggcagc gggtgatcat catggtcccg gtcgccgtcc
    19681 ttcgagacgg atccagccct cgtgggcggc gccgacgtgc agtgcgatgt agggcgccca
    19741 ggcctcgatg acctgcgcgg cctgggtctc gagcacaccc gaaagcgcca cccggccgcc
    19801 cggtgcgaca cgcgccgaga tcgccggcgc gagcacgcac agcgggttgg tgaggatgtt
    19861 ggcgacgacc aggtcgaagg catcgcccag cggcacggcg gagtgctgca ggcgcatgtc
    19921 cgcgtggttg cgcgcggcgt tgtcgcgcgc ggcgtccacc gccttctcgt cgatgtcgat
    19981 gccgagcacc tcgcccgcgc ccagcttcgc tgcggcgatg ccgaggatgc ccgagccgca
    20041 gccgtagtcg agtacgctgc agccgggtac gaccgcctcg cacagccact ccaggcacag
    20101 ccgggtggtg ggatgcgagc cggtaccgaa ggccatgccg gggtcgagct cgatgttgat
    20161 cgcgtcggcg tcgggcgcct cgtgccagga aggcacgatc cacagccggt cggtgatacg
    20221 gatcgggtcg aactggctct gggtgagttg cacccagttc tgctcggcga cggtctcggt
    20281 ggtgaacggc gggacggcgt cgaagcccgc cgcgcgggca gcctcggcga gcatcgcgcc
    20341 gagttcggcc ggatcggcgg cggcgtcgaa gagcgcgatc acccggctat ggtcccacag
    20401 cgcggtgggc aggtggccgg gttcgccgaa ctggggccgc tcggcctcgg tgccggcatc
    20461 ggcgtcctcg atcgagaccg agagcgcccc cgcctccatc agcgcgtcgg agagcgcctc
    20521 ggccttgtcg gcctcggcct gcagggtcac cgagatccac atcgcgcgtc agctccggac
    20581 ttcgttgcgg tcggcgagct tgtgctcgag gtagtggatg ctggtgcagc cctcgttgaa
    20641 gcgcggatcg agcatcagcg tctggtgcag cgggatgttg gtcttgatgc cctcgaccat
    20701 catctcggag agcgcgatgc gcatgcgccg gatcgcctgg tcgcgcgtgt cgccgaaggc
    20761 gatcagcttg ccgatcatcg agtcgtagtg cggcggcacg gtgtagccgt tgtagacgtg
    20821 cgagtcgacg cgaatgccag gcccgcccgg cgtgtgccag ttggtgatgc ggccgggcga
    20881 gggggtgaac ttgaacgggt cctcggcgtt gatccggcac tcgatggcgt ggccgcggaa
    20941 ctcgatgtcg cgctggcgga accacagctt ctcgccggcg gcgatgcgga tctgcgcctg
    21001 cacgatgtcg atgccggtga tgagctcggt gaccgggtgc tcgacctgca cgcgggtgtt
    21061 catctcgatg aagtagaact cgccgttctc gaacaggaac tcgaaggtgc cggcgccgcg
    21121 atagccgatc ttgcggcagg cctcggcgca acgttcgccg accttggcga tcgccttgcg
    21181 gtcgatgccg ggagcgggcg cctcctcgat caccttctgg tggcgacgct gcatcgagca
    21241 gtcgcgttcg ccaagataga ccgcgttgcc gtgctggtcg gcgagtacct ggatctcgac
    21301 gtggcgcggg ttctcgagga acttctccat gtacaccacc gggttgccga aggccgcttg
    21361 ggcctcggcg cgggtggtgg tcacggcgtt gagcagcgca gcctcggtgt gcaccacgcg
    21421 catgccgcgt ccgccgccgc cgccggcggc cttgatgatc accgggtagc cgaccgcgcg
    21481 cgcgaccttg acgatctcct tcgggtcctc gggcagcgcg ccctccgagc ccggtacgca
    21541 ggggacgccg gcggccttca tggcgtcctt ggcggagacc ttgtcgccca tcaggcggat
    21601 ggtctcgggg cgcgggccga tgaagacgaa gccggactgc tcgacgcgct cgccgaagtc
    21661 ggcgttctcg gagaggaatc cgtagccggg gtggatggcc tcggcgtcgg tgacttcggc
    21721 ggcggagatg atggccggca cgttgaggta gctctgcgcc gagggcggcg ggccgatgca
    21781 gaccgactcg tcggccaggc gcacgtactt ggcgtgggtg tcggcctcgg agtgcaccgc
    21841 gacggtcttg atgccgagct cgcggcaggc gcgcaggatg cgcagggcga tttccccgcg
    21901 gttggcgatg aggatcttct cgaacatggc ggcctcagcc gatcacgaac aagggctggc
    21961 cgtactcgac cggctcgccg ttctcgacca ggatggcctt gaccacgccg ctggcgtcgg
    22021 cctcgatctc gttcatcagc ttcatcgcct cgatgatgca caggcgctcg ccgctggcga
    22081 ccttctggcc gagctcgacc agcggcttcg cgcccggtgc gctggcgcgg tagaaggtgc
    22141 cgaccatcgg cgacttgacg atgtggccgt cgggcagctc gtcctcgaca tcggcgggcg
    22201 ccggcgcggc gagaggggcc ggtgcggcgg cgggcgggac ctgggcgtag taggtggccg
    22261 gagcggcggt ggagtgcttg gcgatgcgta ccttttcctc gccttcggtc acctcgagct
    22321 ccgagatgcc ggactcctgg acgagatcga tgagtttctt gagcttgcgc agatccatgg
    22381 tgttctccgg acgggaccgc gttcgccacg gcgggcgctg cggtcgggaa gattcagtgt
    22441 tcgggtttcg tacacacgcc gaaaccgccg cgctcgcgcg gcgggcgggg gaaacggttc
    22501 gtgctgggga gctggttcgc ggacacactc cgccgccgcg gctcgcccaa gcgtgcgggg
    22561 tgcaggcgag acgcctcgtg aagcaccgcc ccgccattcc gaagagatgg gccgtcttct
    22621 ccgtgaggag gagtgggcga gcattttgag tgcttcatgg atgcaagttt gccgcaaatc
    22681 gctgcaaatt gtccacattg gggtgtggcc tcgagccgcc gggcaggcgg gtgtggcgcg
    22741 gtggcgtgcg cggattctgc gctcgcgcgg cgcccgccgc aagccggtcg aggttgtgcg
    22801 gtcgctgtgg ccgggcgcgc gctcaaggcg cggatgggtg tggagcgatg gtgctttccg
    22861 ctgcggcgac gagcgcctcg acctgggcga ggcgggcgcg ctcctggccg cggcgcgggc
    22921 tgcgctcggc tgcggaaggg tagatcgaca ccttcaccgg cacatcgtcc caatcgaagc
    22981 cgaggatggc ctcgggggtg tgcggcgcgg ggcggcgcgg ctcgcggtgt tcgtaggcga
    23041 agtcctggtt gaggaagaag atctcgacgt ccttggcgct ctccgggaag agctcgatct
    23101 cgagctcgga gtagcgcccg gcggtgccat cgagggcgcc gccggtgagg taggggcgaa
    23161 aatcggcgag caggcgcatg acctcgacgg ccgcgctgcg catctcgagc aggcgctgcg
    23221 gctgctcctc gtcctggtag atcgccagcc aggcgcgcag ctcggcctcg atctcggtgt
    23281 tgttgggcag ggcgtcggct tcggtggcgc cgagctgttt cgccgccttg cgcttggcga
    23341 agccgaagtc gctgatgcca tcctcggcca tcatgcgcgc ggcgagcgcg gcaatttcgc
    23401 gccgcaggcc gccgctgcgg gaaacgtggg cgtgtgaggg catggtgggc ctcgggtaga
    23461 atgcgcgccc attgtaatac agccccggtt gcggccggat gaaggcttag cggagcgcga
    23521 aatccccatg cacatccata tcctcggcat ctgcggcacc ttcatgggcg gcgttgcgct
    23581 gctcgcgcgc gcagccggcc ataccgtgac cggctgcgac gccaacgtgt atccgccgat
    23641 gagcacccag ctcgaggagc agggcatcgg gctgatcgaa ggctacgaca gcagccagct
    23701 cgacctggag cccgacgtgt acgtggtcgg caacgcggtg tcgcgcggca acccgctgct
    23761 cgaggcgatt ctcgaccgcg gcctgccgta tgtctccggg ccgcagtggc tggccgagca
    23821 tgtgctcgcc gggcgctggg tgctggcggt ggccggcacc cacggcaaga ccacgacgac
    23881 ctcgctactc gcctggatac tggaagacgc cgggctgtcg ccctccttcc tggtcggcgg
    23941 cgtgccgcag aacttcggcg tgtcggcgcg tctgaccgag tcgcccttct tcgtgatcga
    24001 ggccgacgag tacgacaccg ccttctgcga caagcgctcg aagttcgtgc attaccggcc
    24061 gcgcacggcg atcctcaaca atctcgagtt cgaccacgcc gacatctttg ccgacctcgg
    24121 cgcgatcgag acccagttcc accacctggt gcgcacgatc cccgcgagcg gtcgcatcgt
    24181 cgccaacgcg cacgaggaca gcctgcggcg cgtgatcgag cgcggctgct ggtcggagct
    24241 ggagtggttc ggcggcgatg gacggtgggc ggtggcgacc ggggcggacg aggtcgaggc
    24301 ggtcttccgc ctcgacggcg tggagcaggg ccgcgtgcgc atgccgctcg ccggcagcca
    24361 taaccgcgac aacgcgctcg ccgcgatcgc cgccgcacgc cacgtcggcg tcacgccggc
    24421 acaggcgatc gccagcctcg gacgcttcgc cggcatcaag cgtcggctgg agctgcgcgg
    24481 cacggtgcgc ggggtgcgcg tctacgacga cttcgcccac catccgaccg cgattgcgct
    24541 caccgtcggc ggcctgcgcc ggcgcgagcc gcagggccgc atcctggcgg tgctcgagcc
    24601 gcgctcgaat acgatgaagc tgggagtgat gaaggcgcag ctgccggcca gcctcgccga
    24661 ggccgacctg gtgttctgcc atgcgcacgg gctgggctgg gatgccgccg aggccctcgc
    24721 gccgctgggc gcgcgcgcgc gcagctacga tcgcctcgat gcgttggtcg cggacgtggt
    24781 cgcggcggca cggccaggcg accacgtgct ggtgatgagc aacggcggct tcggcggcgt
    24841 gcaccagaag ctgctcgacg cgctcggcac ttaggaggtg ccgctggcgg cgccttcgtg
    24901 gggaggcggc cgcctgcgat gcccgccgcc gtcgctcagt tgcgccgtgc gccggtcggg
    24961 ttgtcgagcc ggcgtgcttc ctcgtcgctg atgtactcga acacccgcac caccttgcgc
    25021 acgccctggc tggtgcgcgc cacctcggcg gcagcgtcgg cctcgctgcg ggtgacgatg
    25081 ccgagcagga agacgacgtt ggcctcggtc accaccttga tgttgtgggc agagacggtt
    25141 ccggcgtcga tcatgcgcgc cttcacgttg gaggtgatca aggtgtcgtt gccgcgcgcg
    25201 gtgagattgg agttgggggc gatcgccacc tcgttcacca cgccgcgcac gtgctcgaca
    25261 ccggcgacga tgccgtcgag ctggccgcgc acggtctcgt tgggcgcctc gccggtgagc
    25321 aggacgttgc ggttgtagga cgtgacgttg acatgcacgc tgtcgcccag gcgctcgcgg
    25381 atgcgtgcag aaaccttcca ctcgatgcct tcgtcctcga cgtaggtgcc gctggtgcgg
    25441 cggtccgaga ccatcgccgc gccggcgccg acgccggtgg cgacgaccgg gaagcagccc
    25501 tgcagcagcg gcagcgcgat ggccgcggaa aggcccagga ggagggcacg ccggctggac
    25561 ttcgccggtc tgtcgcggtg ttggggttgg ttcatcagtc ttccactccg agtaagaggc
    25621 agtcgatacc gtcgcacagg cagtgcagga tcagcaagtg gatttccctg atccgggcaa
    25681 cccgctcgtc cggtgtgcac agcaggatgt ctgccggtcc cagcgttgcg gccgtgctcc
    25741 cgccgccggc gccggtcagc gcgatcacgc gcatgtcgcg ctcgtgggct gcgcggatgg
    25801 cgtcgaggat tcgcgacgaa tcggggttgg cggacagggt gagcaggatg tcgccgggct
    25861 ggccgaaggc ggcgatctgg cgggcgaaca aggcctgggt gtcgggatct ccggcgacgg
    25921 gggcgaggct ggagctgtcg gcgctgagcg ccatcgcggc gagcgccggg cgctcgagct
    25981 cgaagccgtt caccagctgc gcggcgaagc gtcgcgcgtc gcccgccgag ccgctgctgc
    26041 cgcagaccag aaccttgccg ctgtcgagca ggctggcggt gatcagctcg accgcgccgg
    26101 cgatcggcgc ggcgagcagt tcgagcgcct cgagcgaggc gcgcatgttg tcttcgaact
    26161 ggtgcgaaat gcggtcgatc aggttcatgc gggatgcgag atctgcgggg gccggagagt
    26221 ctagcacgcg ctctcagccg gcatcgaacg cgcccgggag ccaggtgacg cgcgccggat
    26281 cgagagcgtc gagcagcacc gcgtcgaagc ggcagggcgc atcgcgaaag cggcgccctg
    26341 cgccgcccag ccaccactgc gccgcgatca gcacgcggcg ctgcttggct gcggtgatgc
    26401 tctccgcggc accgccgaag cgaccgttgc ggcgcaggcg cacctcgacg aagacgacgt
    26461 ggctgcggtc gaggcagacc aggtcgacct cgccgccgcg gcagcgcacg ttgcgcgcga
    26521 tcacgcgcag gccgtgcgcg gcgaggtgct ctgcggcgag tgcctcggcc gcagcgccat
    26581 gcgcttgcgc cggcgtcggg cgcgcgccga tactgtccgc ccccgcgtgc gcgcccctgt
    26641 cgtcctcgcc tgcgccgcgc gtccagcctc cggatctgcc tcccatgacc acctccgctc
    26701 ccttgcccga tcgcccactg tccagtacgc cgtcattgta tgtggtggct acgccgctcg
    26761 gaaacctgca tgacatcacg ctgcgtgcgc tcgccgtgct cgccgcggtc gatgtggtgg
    26821 ccgccgagga cacccgccac agccagcgcc tgctcgatgc gcacggcatt cgcgcgcgca
    26881 tgctggcggt acaccagcac aacgagcagg aggccgccgg ggcgatcgtc gccgagctcg
    26941 ccgccggccg tcaggtggcg ctggtcaccg acgccggtac gccggcggtg tcggacccgg
    27001 gcgcccgcct ggtggcgcgg gtgcgcgccg cggggcatcc ggtggtgccg ttgcccgggc
    27061 cgtgtgcggc ggtggcggcc ttgtccgtgt cgggcttcgc cgagggcggt ttccgcttcg
    27121 tcggcttcct gccggccaag ggcggggcgc gtgcggcggc gctgcgcgag ctcgccgacg
    27181 agcgcgccgc gatggtgttc tacgaggcgc cgcatcgcat cgccgagtgc atggccgaca
    27241 tggagcaggc cttcggcggc gtacgcgagc tgctgatcgc gcgcgagatg accaagctcc
    27301 acgagcagat cgtgcgcatg ccgctcgcgc aggctgcggc ctggctcgcc gccgacacga
    27361 accgcctgcg cggcgagttc gtgctggtgg tggagggcgc tccggccggc gaggcggtgg
    27421 atgcgaacgc gcggcgggtg ctcgagctgc tgctcgcaga gctgccgctc aagggcgcgg
    27481 cgcggctcgc cgccgagatc accggggcgc cgcgcaaggc cttgtacgcg ctcgcgctcg
    27541 agcgcaaggg cggcgattcg ccggcggcgt gacgcatgca cggccgcgcc ggccgtgcgc
    27601 gccttcgaag cgcctataat cggcgggtca cacgaggaac gccccgatgc aatcgattac
    27661 cttgatccgc cccgacgact ggcatctgca cgtgcgcgac gacgctgcgc tcgacgcggt
    27721 ggtgccccac accgcagccc gcttcggccg ggcgctgatc atgcccaacc tgaagccgcc
    27781 ggtcaccacc accgcgcagg cgctcgccta ccgcgagcgc atcctcgccg cggcgcgcgg
    27841 atcgaggttc gagccgctga tgagcctcta cctcaccgac aacctgtcgc cggacgagat
    27901 cgaccgcgcc tccgcgagcg ggcacatcgt cgcctgcaag ctctaccccg cgggcgcgac
    27961 cacgaactcc gacgccgggg tcaccgcgat cgacaaggtc tatcccgtgc tcgagcgcat
    28021 ggagaagctc ggcatggtgc tgtgcgtgca tggcgaggcc accggggcgg aggtcgatgt
    28081 gttcgaccgc gagcgcgtct tcatcgagcg cacgctgtcg ccgctggtgc ggcgcttccc
    28141 cgggctcaag gtggtgttcg agcacatcac caccgcggag gcggcgcagt tcgtgcgcgc
    28201 cgcggggtcg cacgtcgccg ccacggtcac cgcgcaccac ctgctgctca accgcaacgc
    28261 gatcttctcg ggcggcatcc gcccgcacca ctactgcctg ccggtcctca agcgcgagag
    28321 ccaccgcgag gccctggtcg cggcggtcac ctcgggcaat gcgcgcttct tcctcggtac
    28381 cgactccgcg ccgcatgcgc gcagcaccaa ggagaacgcc tgcggctgtg cagggtgcta
    28441 caccgcgcat gcggccatcg agctctacgc cgaggtcttc gacgccgccg gcgcgctcga
    28501 tcgcctggag gccttcgcca gcctgaacgg accggccttc tacggactgg cgccgaacgc
    28561 cgacaccatc acgctgcggc gcgagccctg gagcgtgccg gcgagctacc cctatctcgg
    28621 cgaggatccg ctggtgccgc tgcgcgccgg cgagcaggtg ggctggaagc tggtgggagg
    28681 ggcctgaaat gggtgtgcgc atgcatgagg cgggcatccg ggacgcggcc gcgcgcgtgg
    28741 cgacggcccg gcgcggtgtc cgctgcggtg ccgggggcgc gctgcgccgc ggccttgctg
    28801 cggtcggcct gctcgcagtg ctcgccggct gcgagaacag cgccaccgcg tacatgatcg
    28861 aaggcagcca gcacgcgctg atcctggtgc gcgagcagaa gttcttctgg gacgacgaac
    28921 tgcgccaggc cgtggtggtg tcgcgcctgc ccgcctgcca gaagcgcatc cgcatccatc
    28981 cgagttccac gacgctcgtc gagatgaagg tctatgccgc cggcgacggc ctgtgggcgc
    29041 tgcatcaggg cgtgcgctgg tatctcgccg gcaccgagga gtgccgcctg caggactggg
    29101 acaacccggg cgaccgcccg ccgggcgcgc tgctcggcag cttcgcgctg aaggacggcg
    29161 agcccgcctt cgttgctgcg cccgccgcca aataagccgg gcggcgccct gccggcgcgc
    29221 gtataatccg cgccggaagt ccgccaggca gtcgctgcgc acctcgtcgt gcgtggagga
    29281 aagtccgggc cccgcagagc aggatgccgg ctaacggccg ggcgtcgtga ggcgacggaa
    29341 agtgcaacag agaacagacc gccgatggcc ttcgcaagaa ggatcaggca agggtgaaac
    29401 ggtgaggtaa gagctcaccg caggactggc aacaggactg gcacggcaaa ccccatccgg
    29461 ggcaaggcca aataggggag catcggcgtg gctcgcgtcg ctcccgggta ggctgctaga
    29521 gcgccacggc aacgtggtgc ccagaggaat gactgcccga cgtctccggt tcgccggcgg
    29581 cgttcgacag aacccggctt atcggtggac ttcccacttc tcccctgttt ttgaccgcga
    29641 atgccgcctc cgcgcgcggc attcagcagc ggtcgccccc attcttaacg aatccgccct
    29701 cgcaaacggg ccggattgcg ccggcattcc cactttttcc cactgcgccc tatgcgcggc
    29761 ccgatttcgc gtgccgcgcg aacgtccgtg cgcatctccc ttgatttttc aggatttctc
    29821 cacgtcttgg cgtggcgcgg taagtcattg tgcaacaaag ggattccgtt tctgcaacct
    29881 tgacccggca tggcctttcc actaaagtgg gttcaagtgg aaaaaagtgg ggaaaagtgt
    29941 cgttccgatg ctttcccaaa gccgtcaggg ggttcgatgt tccagggagc ggtggcgctc
    30001 aatctcgatg cgaagggacg ccttgcgatt cccgcgcggc atcgtgatgc cctggccgtc
    30061 gataacggcc aggtggtgct gaccgcccat ccgcacggct gctgcctcgt ctaccccgtt
    30121 cccgcctgga atccgatccg cgaccacgtg ctgcgggcac cgagcctgga tccgcaagcg
    30181 gcgatgctca agcgcctgct cgtgggcttc gcccaggaag agacgctcga cgccgccggt
    30241 cgcgtgctgg tggcgtcctc gctgcgcaag ttcgctgcgc tcgagaagca ggtctggctg
    30301 gtcggccagg gcacgcattt cgagctgtgg tccgatgagc gctgggagaa gcagcagcag
    30361 gcgatgctcg acctggtcaa taccggcctg ccgcccgggt tcgagagcct cgcgctgtga
    30421 cctccgccca tgcccacgtc agcgtcctcc tctccgaagc ggtcgacgcg cttgcgatcc
    30481 gtgccgacgg catctacgtc gatgggacct tcgggcgtgg cggccatagt cgcgccgtgc
    30541 tcgcccaact cggaccgcag gggcgcctga tcgccttcga ccgcgatccg gcggcgatcg
    30601 ccgccggaga ggcggtgggg gatgcgcggc tgacgctggt gcattcggca ttcagcgcgc
    30661 tcgacgacga gctcgtgcgc ctcggcgtgc aggcggtgga tggtgtgctg ctggacctcg
    30721 gggtgtcttc gccccagctg gacgacgctg cgcgcgggat gagctttcgc ttcgacgccc
    30781 ccctcgacat gcgcatggat acgagccgcg ggcagaccgt ggcggaatgg ctggcggagg
    30841 cgtccgtcgg acagatcacg gaggtcatca gggaatatgg agaggaacgg tttgctcatg
    30901 cgattgcaaa ggcgattgca actgctcggg cagggggggc tgtcgcaacc actggacaac
    30961 ttgccgcgct cgtggaaaaa gcggtccgca cgcgcgagcc ggggcagcac ccggcgacac
    31021 gcaccttcca ggctcttcgg attttcatca atcaggagct caaggagctg agcggagtgc
    31081 tgcccgtctg cgtgtcccgg ctgcggccgg gcgggcggct ggcggtgatc agcttccact
    31141 cgctcgagga ccgcatcgtg aagcgcttca tgcgtgacga gtcgcgtccg ccgctgctgc
    31201 cgcgccggct gccggtcagg gcggcagacc tgcctgcgcc gcgcctgcgg ctcgtcggca
    31261 aggcgacgcg tccgggcgag gccgaggtcg cggccaaccc gcgtgcgcgc agcgcggtgc
    31321 tgcgcgtggc cgaacgcacg gaggcgccct gatggtgcga atcgacgccg tcctcgtcgc
    31381 ccttgccgtc gccagcgcgc tcggcgtggt cgcctcgcag catcaggcgc gccgcctcca
    31441 cggcgagtac gagcgcgagc aggcgcgcgc gcaggcgctc gaggtcgagt gggggcagct
    31501 ccagctcgag cagagcacct gggcgacgca cgggcgcgtc gagaagctcg cccgcgatcg
    31561 cctgcacatg caagtgccgc ccgaagggca ggtgctggtg gtggagcctc aatcatgaaa
    31621 aagcaacgta ccgtcacctt caatcacaat ccgctgctca agcgcgagct gccggcatgg
    31681 cggccgcgca tcgtcatgct cgcgctgatg gggtgttcgc ttgcactggt cgggcgtgcg
    31741 ctctacctgc agggggtcaa tgacgatttc ctccaggcca agggtgcatc gcgctatgcg
    31801 cgcgtgctcg aggtgcccgc cacccgcggc cgcatcaccg accgccatgg cgacatcctc
    31861 gcggtgagca cgccggtgcg cgcagtctgg gcgctgcctg cggacgcacg cctggagccc
    31921 gcccaggtgc gcgagctcgc gcgcctgctc gagatggatg ccaacgagct caacggcaag
    31981 ctcgccgcag ggcgcgactt cgtctacctc aagcgccagg tgccgcccga ggtcgcgcag
    32041 gcagtcgccg acctgcgcct gcccggcatc caccagcaga aggaataccg tcgctactac
    32101 cccggcggcg aggtgatggc gcacatcctc ggcttcaccg acctcgagga ccgcggccag
    32161 gagggcatcg agctcgcttt cgacaagcgc ctgtcgggtc gcgccggagc gcgtcgcgtg
    32221 atcaaggacc gccgcggcca gatcgtcgag gacgtcgagg ccatccgtcc cccgcgcgac
    32281 ggcgacgatg tcgcgctgtc gatcgacggc aagatccagt atctcgcctg gtcggcgctg
    32341 cgcgaggcga tggaggagca caaggccaag gcggccgccg cggtcgtgct cgatgtgcgc
    32401 agcggcgagg tgctcgcgct ggtcaacgca ccgaccttca atccgaacaa tcgcgccaac
    32461 ctcactggcg cgcagctgcg caaccgggtg ttcaccgacg ccttcgagcc cggctcggtg
    32521 atgaagccct tcatcgccgc gctcgcgctc gagcgcggca aggtcaggct caataccccg
    32581 atcgacaccg gcagcggccg catgaccatc gggaccgcga ccatctccga caccaagcgc
    32641 catggtgtca tcaccatggc gcaggtggtg cagaagtcct ccaacatcgg caccgtgaag
    32701 atggctcagc agctcggcgc cgacgagatg tggcatctct tcgatcagct cggcttcggc
    32761 accccgctca acctcggctt ccccggcgag acctccggcc ggctgcgtcc ggccaagagt
    32821 tggcggccga tcgagcaggc gaccatgtcc tacggccacg gcatctcgac gagcctgatc
    32881 cagatggcgc gcgcctacct cgtgttcgca cgcgagggtg agctggtgcc gctgtcgctg
    32941 acgcgggtgg agggcgcgcc gagctcgggg cggcgcgtgt tctcggtcga cacggcgcgc
    33001 cagatgcgca ccgtgctggc gatggcggcg ggccccggcg gcaccgcgat ccgcgcccag
    33061 gtgcccggct acacggtggc gggaaagacc ggcactgcac acaagctcga ggacggccgc
    33121 tacgcgcgca agtacatctc gtccttcgtc ggcttcgcgc cggcgagcga tccgcgcatc
    33181 gtcgtcgcgg tgatggtgga tgagccctcc gcgggccatc actacggcgg tacggtcgcc
    33241 gcgccggtgt tctcgcgcat caccgagggc acgctgcgca cgctcggtgt cgccccggac
    33301 atgccgctga ccccgctcca gcttgcccgg cgcggtgcgg acgaggccgc cagcgctggc
    33361 gtcggcaggg agaacatgtg agcgccgcgc aagccctcgc cgtgctcgat cgcctgcgcg
    33421 cgctcggggt gcacgcggac gacatcagcg cggattcgcg cagggcgggg tcgggctgcg
    33481 tgttcgcggc ctggcccggc cagcgtaccg atggtcgccg tttccttgcc gatgcggccg
    33541 cgcgtggcgt ggccgccgtg ttgtgggaag acggcgacgg ttttgccgct cccccgcttg
    33601 cggtgccggg ttttggcgtg cgcggcctgc gcgagcttgc cggctacctc gcgcacgagc
    33661 tccacggccg gccttcgcag gcgctgtggc tggcgggcgt caccggcacc aacggcaaga
    33721 ccaccgtctc gcagatgctc gcgcgtgcgc tcggcgatct cggccagccc tgcggcatcg
    33781 tcggcacgct cggctgcggc ttccccgatg cgctcgagga gggcctcaac accacgcccg
    33841 acgcgctcga gctgcagcgc tggttcgccc gcttccgcga ccagggggcg gtggcggcgg
    33901 cgatggaggt gtcctcgatc gggctcgacc aggggcgggt caatggtgcg cagttcgacg
    33961 tcgcgatctt caccaacctg agccgcgacc acctcgacta ccacggcacc atggaagcct
    34021 acgccgaggc caaggcgcgc ctgttcgagc gcccggagct ggcggcctgc gtgatcaacg
    34081 tcgacgaccc ctggggcctg gcgctggcgc gcaggctcgt cgccgcgggg cgcacggtga
    34141 tcgcctgcac gctctatgcg gccaatgccg acgcggtgcc cggcgcgcgc gtgctgcgcg
    34201 ccgaccgcct gcaggccgcg cctgcggggc tgcgcttcac cctcgtctgg gaagggcgcg
    34261 aggccgagat cggcgtgcgc atggtggcgc acttcaacgt ctccaacctg atcgcggtcg
    34321 ccggcgcctt gctcgcgcgc ggcatcgcct tcgacgagct gccgccggtg ctggggcggc
    34381 tttcgccgcc gcagggtcgc atgcagctgg tcggcggagt gtgcgagccg ctggtggtga
    34441 tcgactacgc gcactcgccc gatgccctcg ccaaggtgct cgaggccttg cgcggcacgg
    34501 tgcatagccg gcgcggccgc ctgacgtgcg tgttcggctg cggcggcgac cgtgatccgg
    34561 gcaagcgccc gctgatgggc gagatcgcca gcgcgatcgc ggatcgcgtg gtgatcacca
    34621 gcgacaaccc gcgctccgaa gacccgcagc gcatcgttga ggccatcgcc gccggcgccg
    34681 gtccggcggc cgaacgcgtg gtcgaccgtg cgcaggcgat cgcccgtgcg gtcgccgagg
    34741 cgcaggccga tgacgtggtg ctgatcgccg gcaagggcca cgagccctat caggaaatcc
    34801 tcggcaaacg cctgccgttt tcggatctgg agcaggcgaa gcgtgcgctc gccgcctggc
    34861 atgcaaggga gaagggccaa tgatgagcct gcacgacgcc gcacgcgcgc tcgcggtcca
    34921 tggggcgcga gcgaccgggg aggggcgctt cgacagcgtc ggcaccgaca cccgcgcgct
    34981 cgcgcccggg cagctcttcg tcgcgctgcg cggcgagcgc ttcgacggcc acgacttcgt
    35041 cgccaccgcg gccaaggccg gcgcggccgc ggcgctggtc gatgccgcct gggttgccgg
    35101 caagagcgac gccggcctgc ccctgctggt cgtggacgac acccggcgcg cgctcggcac
    35161 gctcgcggcc gcctggcggg cacgcttcgc actgccgctc atcggtatca ccggcagcaa
    35221 cggcaagacc acggtgaagg agatgtgcgc cgcgatcctg cgtgcgcagg cgagccgaga
    35281 cggcttcggc gaggagtcgg tgctcgctac ccgcggcaac ctgaacaacg acatcggcat
    35341 gccgctgacc ctgctcgagc tgcgcgactt ccaccgcgcc gcggtgatcg agatggggat
    35401 gaaccaccct ggcgaaatcg gctacctgag cgcgctcgcc cagcccaccg tggcgctggt
    35461 gaacaacgcc cagcgcgcgc acctgcaggg catgggctcg gtcgacgagg tcgcgcgcga
    35521 gaagggcgcg atctacgacg gcctgggcgg cgcgggcgtg gcggtgatca acgccgacga
    35581 cccgcacgcc ggctactggc gcgcgctcaa tgccgggcgg ccgattgtga cattcggtat
    35641 cgaccagccg gcggacgtgt tcgcgcggtg taccctgcgc ggcctcggct cgcggctcga
    35701 actcgatgcc ccgcaaggga agatcgattt caccttgcag gtgccgggtc tgcacaacgt
    35761 gcgcaacgcc atcggcgcgg cggctgcctg cctctcggca ggggtgtcgc ccgaggcggt
    35821 ggcccagggg ctggcaggtt tcgccggcac gcgcggccgc ctgcagcgtc gggccgggcc
    35881 gcagggtgcg ctggtcctgg acgattcgta caacgccaat ccggattcgg tgcgtgcggg
    35941 catcgacgtg ctcgccgcca tgccgggcca cacctggctg gtgctcggcg acatgggcga
    36001 ggtcggcgag accagcgccc aggtccacga cgaggtcggc ggctatgcga agagcaaggg
    36061 catcgacggc ctcttcgcgc tcggcgacat gagcgcggtg gcggcgcaca acttcggtga
    36121 gggcgcgcgc cacttcagct cggcggaggc gctcgtcaag gcgctcgcgc cgcacctgga
    36181 tgccgactcg gtggtgctgg tgaagggctc gcgcttcatg cgcatggaaa gggtggcgga
    36241 tgcgcttgcg gcaatgcaca atcccgcccc ttcaacggaa accggctcct gacatgttgt
    36301 tggaactcgc cctctggctc agccaggaca ttcgtggctt caacgtcttc ggctatatca
    36361 cgctgcggac ggtgctcgcc gcactcaccg cgctggcgat ctcgctgatc gccggccccg
    36421 ccgtcatccg ctggctggct gccaagaaga tcggccaggc cgtgcgcgac gacggcccca
    36481 agtcgcatct gaccaaggcg ggcaccccga ccatgggtgg tgcgctgatc ctgatcgcga
    36541 tcggcatcac cgtcctgttg tggggcgatc ttcgcaacga ctacgtatgg gtgacgctgc
    36601 tcgtgaccct gggcttcggc gcggtaggct gggtcgatga ctggcgcaag gtggtgcacc
    36661 gggatccgaa ggggctggcg agccgctgga aatacctgtg gacctcggcg atcgcgctcg
    36721 ccgcggcgat ctacctcggc atcagcgccg ataccccggc cgagaccgag ctgatcgtgc
    36781 ccttcttcaa ggccgtggcc tatccgctgg gcatcttcgg cttcgtcgcg ctgacctact
    36841 tcgtcatcaa cggcaccagc catgcggtta acctcaccga cggcctcgac ggcctggcga
    36901 tcatgccgac ggtgatggtg gccggtgcgc tggcgatctt cgcctacgtc gccggccacg
    36961 ccggcttctc caagtatctc ggcgtgccct acgtcgcggg ggcgggcgag ctcgcggtgt
    37021 tctgcggcgc gatctgcggt gccggcctcg gcttcctgtg gttcaacgcc tacccggcgg
    37081 aggtcttcat gggcgatgtc ggcgcgctcg cgctcggcgc cgcgctcggc accatcgcgg
    37141 tgatcgtccg ccaggagatc gtgctcttca tcatgggtgg cctcttcgtc gccgagaccc
    37201 tgtcggtgat ggtgcaggtg ctctacttca aggccaccgg cggcaagcgc atcttccgca
    37261 tggcgccgct gcaccaccac tacgagctgg gcggctggaa ggaaacgcag gtggtggtcc
    37321 gcttctggat catcaccatc atgctggtgc tgttcggcct gtcgacgctg aaactgcgat
    37381 gagcgcactc acgggcaaac acatcctcgt cctcgggctc ggcgaatcgg gcctggccat
    37441 ggcgcgctgg tgcgcgctgc gtggcgcgcg cgtgcgcgtg gccgacagcc gcgccctgcc
    37501 gcccgggcgg gatgcgctga aggcggacgc cccgctcgcc gagctcttcg tcggcggttt
    37561 cggcgacgag gtgctcgacg gcgtcgacct ggtcgccctc agcccaggcc tcgacccgcg
    37621 cgtcggggtc gccgccgagg cacgtcggcg cggcctgccg cttaccggcg agatgagcct
    37681 gctcgcgcag gcgctcgacg aactcggcgt gcgcgcgcag acctgcatcc tcgcgatcac
    37741 cggtaccaac ggcaagacca ccaccaccgc actcgccgcg gcgctcgcgc agtccgccgg
    37801 cctcgatgcg gtcgctgccg gcaacatcag cccggcggcg ctcgacgtgc tcatggagcg
    37861 cctggagatc ggcgccgcgc tgcccgcgtg ctgggtgctg gagctctcga gcttccagat
    37921 cgagaccatg caggggctgg acgccgaggc ggcgaccgtg ctcaacgtca ccgacgacca
    37981 cctcgaccgc tacgccgacc tcgaggaata tgccgctacc aaggcggcga tcttccaggg
    38041 tgcgggcgtg caggtgctca accgcgagga cgcgcgcgtg gtggcgatgg cgctgccggg
    38101 ccggcgcacg ctccgcttcg gcaccacggc gccggcggcc gactccgact acggcctggc
    38161 cgaccacgac ggccgcgcct ggctgatgcg tggcagcgag cgcctgctcg cccccgacga
    38221 attgccgctc gccggccgcc acaacgccgc caacgcgctc gccgcgctcg cgctctgcga
    38281 gggcggcctg ggcatcgaac cgcaggccct gattcccggg ctgaaggcct tccgaggcct
    38341 gccgcaccgc gtcgagctgg tcgccgagcg cgccgacggc gtgcgcttct acgacgactc
    38401 caagggcacc aacgtcggcg ccaccgtggc ggcgctcgcc gggatggact gcccggtggt
    38461 gctgattgcc ggtggcgacg gcaagggcca ggacttctcg ccgctcgccc cggtgctcgc
    38521 cggcaaggcg cgcgcgctgc tgctgatcgg ccgtgacgcc ggccgcatcg atcaggcggt
    38581 ggcgggctgc ggtgtggcga tcgagcacgc gcccgacctc gacgctgcgg tggtgcgcgc
    38641 caacgccttc gcgcgggcgg gcgacgcagt gctgctctcg cctgcctgcg ccagcctcga
    38701 catgttccgc aactacgccc accgcgcgga ggtcttcgtc gccgcggtgc gccgcctgcc
    38761 gggagtgagc ccgcgatgaa gttcgccagt accctcaccg gcctgctcca gcgcggtggc
    38821 ggcgcccccg atccggcgcg cgcggccgcc gatcgcctgg gacgccacgg cgcgccggcg
    38881 cgcgagctcg acctgctgct gatctggtcg gcggtcggcc tgctgctgct cggcctggtg
    38941 atggtgtatt cggcctcgat cgcgatcgcc gagggcagcc gcttcaccaa ctatcaggcg
    39001 cacttcttcc tgctgcgcca cgcggtcttc ctcgccgtcg gcatcggcct cggactggtg
    39061 gccttccagc tgccgatggc gcgctggcag cagctcgccc cggcgctctt cgtcgccggc
    39121 gtggtcctgc tggtggtggt gctgatcccg ggcatcgggc gcgaggtcaa tggcgcgcag
    39181 cgctggctct cgctcgggcc ggtgaacctg cagccctccg agctcatgaa gatcttcgcc
    39241 gcgctctacg ccgccgacta cacggtgcgc aagctcgacg tcatgggcag cttcatgaag
    39301 ggcttcgtgc cgatgatggc ggtgatcctg ctggtcggct tcctgctgct gcgcgagccc
    39361 gacttcggtg ccttcgtggt gatcaccacg atcgccttcg gcgtgctttt cctgggcggc
    39421 gtgaacgtgc gcgtgttcgt gctgctcgca gtggtggcgg tgatcggctt cgtgatcctg
    39481 atctggacct cgccctatcg ccgcgaccgc atcttcggct tcatggaccc ctggcaggac
    39541 gcctacggca agggctacca gctctcccac tcgctgatcg ccttcggtcg tggcgagtgg
    39601 ttcggggtcg gcttgggcgg cagcgtcgag aagctcttct acctccccga ggcgcacacc
    39661 gacttcctgc tcgcggtgat cgcggaagag ctcggcttcg tcggcgtgct gacggtggtg
    39721 gcgctgtttg ccttgatcgt acaccgcgcc ttcatcatcg gccgcgaagc ggtcaagctc
    39781 gagcgctact tcgccggcct ggtcgcccag ggcatcggcc tgtggatcgg catccagtcc
    39841 ttcatcaaca tgggcgtgaa catgggcctc ttgcccacca agggtctgac cctgccgctg
    39901 atgagcttcg gcggctcggg catcgtcgcc aactgcgtcg cgctcgccat cctgctccgg
    39961 gtggactggg agaaccgcca gctcatgcgc ggggggcgta catgaagacg ctgatggtga
    40021 tggccggcgg caccggcggc cacatcttcc cgggcatcgc ggtcgccgag gagctgcgcg
    40081 cacgcggctg gcgcatcgtc tggatgggca accccgaggg catggaggcg cgcatcgtgc
    40141 cgccgcgcgg ctacgacacc gcctgggttc gcttcggcgc gctgcgcggc aagggcctgt
    40201 tgcgcaagct catgctgccg gtcaacctgc tctccggctt ctggcaggcg ctgcgcgagc
    40261 ttcgccgcgt ccgccccgac gtggtgctcg gcatgggcgg atacatcacc tttccgggcg
    40321 gcatgatggc cgcgctgctc gggcgaccgc tcgtgctgca cgagcagaac tcggtcgcag
    40381 gcctggccaa ccgcgtgctc gcccgcgtcg ccgatcgtgt gctgagcggc ttcccagcgg
    40441 tgctggagaa ggccgagtgg atgggcaacc cggtgcgcgc cgacatcgcc gcggtgctgc
    40501 cgccggccga gcgcatggcc gggcgcgagg gcccgctgcg cgtgctggtg gtgggcggca
    40561 gcctgggcgc cgcggtgctc aacgagaccg tgccgcaggc gctgctgcgc cttcccgccg
    40621 agcagcgccc gacggtggtg caccaggccg gcgagcgcca gatcgaggcc ttgcgcgcgg
    40681 cctacgcgcg cgcgcaggtc gagggcgagc tgcgcccctt catcgacgac atggcggcgg
    40741 cctatgccga cgccgacctg gtgatctgcc gcgccggtgc gctcaccgtg gccgagctcg
    40801 ccgcggccgg ggtggccagc ctgctggtgc ccttccccta cgcggtggac gaccaccaga
    40861 ccggcaacgc gcgcttcctc gccgaccgcg gcggcgccta cctgctgccg caatccgaac
    40921 ttacgcccga ccgtctcgcg ggcatcctgt ccagcctgga ccgcggccgc ctgctgcaga
    40981 tggccgagaa cgcgcgcgcg ctcgcgaagc cgctcgcagc cgtcgcggtg gcccacgtgt
    41041 gtgccgagct gggcggtgga gaacaagcat gaagcacaag gtcaggaaca tccacttcgt
    41101 gggcatcggc ggctcgggca tgagcggcat cgccgaggtg ctcgccaacc agggctaccg
    41161 cgtcagcggc tccgacctcg gcgacaacgc cgccacgcgc cgcctgcaga agatgggcgc
    41221 gcacgtggtg cgcggccacg acgcgggcaa cgtcgccgac gccgacgtgg tggtggtgtc
    41281 gaccgcggtg aaggccgaca accccgaggt ggtggcggcg cgcgagcgcc acatcccggt
    41341 ggtgccgcgc gcgcagatgc tcgccgagct gatgcgcttc aagcacggca tcgcgatcgc
    41401 cggcacccac ggcaagacca ccacgacctc gctggtggcg agcatcctcg ccgagggcgg
    41461 catcgatccc accttcgtga tcggcggccg cctcaacgcg gccggcgcca acgcgcgcct
    41521 gggcaccggc gactacctgg tggccgaggc ggacgagtcc gacgcctcct tcctgctgct
    41581 caacccggtg atctcggtgg tcacgaacat cgacgccgac cacatggaca cctacggcca
    41641 cgacttcggc cgggtcaagc aggccttcgt cgacttcctt caccgcctgc cgttctacgg
    41701 cgtggcggtg ctgtgcgagg acgatccgaa cgtgcgtggg atcatgcccc aggtcgccaa
    41761 gcagatcgtg cgctacggcc tctccgagac cgccaacatc cgcgccgaga acgtccgcgc
    41821 cgacggcggg cgcatgctgt tcgactgcgt gcgggtcaac ggcacgacgt cgcggctgtc
    41881 gatcgagctc aacctgcccg gcctgcacaa cgtgctcaac gcgctcgccg cgatcgcggt
    41941 ggcgaccgag gtgcaggtgc cggacgcagc catcatcaag gcgctggccg agttcaacgg
    42001 cgtcggccgg cgcttccagc gctacggcga ggtcgcgctg ctcgaccagg acggcgacga
    42061 ggctggcagc ttcacgctgg tcgacgacta cggccaccac ccggtggaga tggcggcgac
    42121 catcgccgca gcgcgcggcg cctttcccgg tcgccgcctg gtgctggcct tccagcccca
    42181 tcgtttcacg cgcacgcgcg actgcttcga ggacttcgtc aaggtgctgt cgaccgtcga
    42241 tgcgctgctg ctggccgagg tctatgccgc cggcgagacg ccgatcgtcg ctgccgacgg
    42301 tcgctcgctc gcgcgcgcga tccgcgtcgc cggaacggtc gagccggtct tcgtcgagga
    42361 aatcgccgag atgccgcgcg tgatcctgtc cgccgcgcgc gacggcgacg tcgtcatcac
    42421 catgggagcg ggcagcatcg gtgcggtgcc gggcaagctc gccagcatcg aggaagcagt
    42481 gtgaaggccc ggttcggaaa agttgcggtg ctgttcggcg gttcatccgc cgagcgtgaa
    42541 gtgtccctga tgtcgggcag ggcggtgctt gccgccttgc agtccgccgg cgtggatgcg
    42601 cacgccttcg atcccgctga gcgcgacctc cacatcctga aggaagaggg cttcgagcgc
    42661 gccttcatcg ccctccacgg gcgcggcggc gaggacggca cggtgcaagg cgcgctggag
    42721 ctgatgggta tcccctacac cggcagcggc gtgatggcct ccgcactctc gatggacaag
    42781 tggcgcacca agatggtgtg gctctccgct agcctgccca cgccgcgcta tgcgatcctg
    42841 gagcacgaca ccgactggga cgccgtggtg gccgagctcg gcctgccgat cttcgtcaag
    42901 ccggtgcacg agggctcgag catgggcgcg accaaggtgg tcgaggtcag ccagctgcgc
    42961 gcggcctggg aactcgccgc gcgctacgac agcctggtga tcgccgagga gttcatcgcc
    43021 ggcgccgagc tcaccgcgcc cttcctcgag gatcgcgcgc tgccgctcgt gcgcatcgtc
    43081 gccccggacg gcaactacga ctaccagcac aagtacttca ccgacgacac ccgctacgac
    43141 tgtccctgcg gcctgcccgc ggcgcaggag gccgagctgc aggcgctggt gatgaagtgc
    43201 gcgcgcgtgc tcggttgccg cggctgggga cgcgccgatc tcatcctcag cgaggatggc
    43261 cgcccctacc tgctcgagat gaacacctcg cccggcatga ccggccattc gctggtgccg
    43321 atgtcggcgc gcgtggcggg gatggacttc acctcgctgt gcctcgagat cctgcaggga
    43381 gcccgtcttg gctgaagccg gcatccgccc cgcgtcgatc cgctccgccc gccgtccggc
    43441 ggcgggcggg cctgcgcgtg cgggtgtcga gcgcggcctg tggcaccggc ctgcgctgct
    43501 caacctgatc tccgacctgc tcaccctggg tgcggccgtc gcgctcggct gggcgctggt
    43561 gatctggttc gtttcgcgac ccctgttccc gctgcgcgag ctggtggtgc tcaccgagcc
    43621 cagccaggtg accgcggagc agctcgacta tgccgcccgc ctcgcggtgc agggcaactt
    43681 cttcacggtc gacctcgacg gcgtgaagca gaccttcgag aagctgccct gggtgcgcaa
    43741 ggcagaggtg cgccggcgtt ggcccgacgc gctcgaactg cgcctggaag agcacgaggc
    43801 ggtggcctac tggacggtgt ccgagagcgg cgaggcgcgt ctggtcaatc gccagggcga
    43861 ggtcttcgtc gccgcctcca acgccgacat gccccagttc gacggtccgc agggatctgc
    43921 gagttggctg ctcgcgcgcc acgccgagtt ctcggacatg ctgcagccgc tcggtgtacg
    43981 cctcgtcggg ctggcgctgt cggcgcgcga ggcctggcgg ctgcaactcg acaacggcat
    44041 gaccatcgtg ctcgggcgcg agcaggacaa gtctccgctg atggaccggt tgcgccgctt
    44101 catcgcggtg tggccgcgcg tgcatgaaca gatcgacatc gacatcaaga ccgcggacct
    44161 gcgctatgcg agcgggttcg cactgacccc ggccgacgcc tcggtgctgc agcagcccgt
    44221 cgcgcccgcc gcccggaaag gcaggaaatg agcaagcaat acaacgaact gatcgtcggc
    44281 ctggacatcg gcaccgccaa ggtcacctgc atggtcgccg aggtgaagcc cgacgggcgg
    44341 ctcaacgtgg tcggcctcgg cacccagccc accaacggcc tcaagcgcgg cgtggtggtg
    44401 aacatcgagg ccacggtgga cgcgatctcg cgcgtgatcc aggaggtcga ggtcatggcc
    44461 gactgcaaga tccacgaggt ctacaccggg ctcgccggca gccacatcaa gagcttcaac
    44521 tccagcggca cggtcgcgat caaggagaag gaggtctcgc cgctcgatgt ggagcgtgtg
    44581 atcgaggtcg cgcgcgcgat gccgatcccg gccgaacagc agatcctgca catcctcacc
    44641 caggaattca tcatcgacgg ccagggtggc gtgcgcgagc cgatcggcat gagcggtgtc
    44701 cgcctcgagg tcaaggtgca catcgtcacc ggcgcggtgt cggcggcgca gaacgtcatc
    44761 aagtgcgtgc gccgctgcgg cctcgaggtc atggacctga gcctgcagcc gctcgcctcc
    44821 agccacgccg tgctcaccga ggacgagaag gagctcggcg tgtgcatggt cgacatcggc
    44881 ggcggcacca ccgacatcgc ggtgttcacc cagggcgcga ttcgccacac cgcggtgatc
    44941 ccggtcgccg gcgaccagat caccaacgac atcgcgatgg cgctgcgcac cccgaccgcc
    45001 gaggccgagg agatcaagat ccgccacggc gtcgccatgc accacatggc cgaccccgag
    45061 gagatgatcg aggtgccggg cgtgggcgac cgcccgccgc gcaagctctc gcgccaggcg
    45121 ctcgccgacg tgatcgagcc gcgcgtctcc gaactcttcg agctggtgca ggccgagctg
    45181 cgccgcagcg gctacgagga actgctgtcc tcgggcatcg tgctgaccgg cggctcggcg
    45241 gtgatgcgcg gcatggccga gctcgccgag gacgtctttc acatgcccgc gcgcgtgggg
    45301 gcgccgcagt acgacggcgg cctcgccgac gtggtctgcc agccgcgcta cgccactgcg
    45361 atgggcctgg tgatggaggg cgcggtgcag cgccggcggg ggctgcaggc acgcgacacg
    45421 cgcagcgtga aacaattttt cgggcgcatg aaggcctggt tcgaacgcaa cttctgaacc
    45481 ggttttcggg cgattttcat tttggatgtg ggccgatcac catcgcttat ttagtagtaa
    45541 acttccggcc aggttactag atgcaggccg gctggcgatc ggtgccgcgc ggggcagtca
    45601 aatcaggagg cgaggctaat gtttgaaatc gttgagaagg aagccaccgg tacggtgatc
    45661 aaggtggtcg gcgtcggcgg tgcgggcggc aacgcggtcg accacatgat ccgcgagggc
    45721 gtgaaggggg tgcatttcat ctccgccaac accgacgcgc aggcgctcaa gcgctgcctc
    45781 gccccggtca aggtccagct cggcaacacc ggcctgggtg cgggctccaa gccggaagcc
    45841 ggccgtgccg ccgcgcagga gtcgcgcgac gcgatctccg cggcgctcga gggcgcgcac
    45901 atggtgttca tcaccggcgg catgggtggc ggcaccggca ccggcgcggc gcccgtggtg
    45961 gccgagatcg ccaaggagat gggtctgctg accgtcgccg tggtcaccaa gcccttcgac
    46021 ttcgagaacc gcatccgcgt cgccgagagc ggcatcgagg agctcacccg ccacgtcgac
    46081 tcgctgatcg tcgtgctcaa cgacaagctg ctcgaggtct tcggcgacga cgccggcttc
    46141 gaggagtgct tccgctccgc cgacaacgtg ctgcgctcgg ccgtgggcgg catcgccgag
    46201 atcatcaacg tccccggcct ggtcaacgtc gacttccagg acgtgcgcac cgcgatggcc
    46261 gagatgggtc gcgccatgat gggctcggcc gaggccgccg gcatggaccg cgcccgcatc
    46321 gccgccgagc aggccgcggt gtcgccgctg ctcgagggca ccgagctctc cggcgcgcgc
    46381 tgcgtgctga tcaacatcac cgcgagcaag tcgctgaaga tgtcggaagt gcgcgatgcg
    46441 gtgaggaccg tgcaggcctt cgccgcaccc gaggccttcg tcaagtacgg caccgtgttc
    46501 gacgacacca tggaagaccg catccgcatc accgtggtcg ccaccggcct cggcgcgccg
    46561 cgcgccgcgc gccagccggt gatgcaggtg gtgcagggta ccggcaccta cggcccgtcg
    46621 atgggcggtg cggtcgacgt gaccaacctc gacgtgccgg cggtgatgcg cagcggtcgc
    46681 cgcaccaccg tcgaggcgat gagcaccagc ggtgtcggca cctacgacat cccggccttc
    46741 ctgcgccgcc aggcggactg accccgcccg ggtggccgcc gccgcggcgg ccacggaccg
    46801 aaacccccgc acgggccgcc gcctccggcc cgcgcggggg tttcgccgtc tacgccgcgc
    46861 gcaacatccg cttgcgcaat agcccggatg catcgctgcg atcgcagggg ggcgccgggg
    46921 gtgcatgtta aaatccgcca tcgaaaaagg aacgagacca tgatccggca gcgcaccctc
    46981 aaatccgtcg tcaaggcgac cggcgtcggc ctgcacggcg gtcgcaaggt gaccctgatc
    47041 ctgcggccgg cggcgcccga caccggcatc gtcttccacc gcgtcgatct cgacccgccc
    47101 ctgagcctgc ccgccgaccc ctacgcggtg tgcgacacgc gcatgtgctc gggcctggag
    47161 cagggcggcc acaaggtcgg cacggtcgag cacctgatgt cggcgcttgc cgggctgggc
    47221 atcgacaacc tgcatgtgga cgtcgacgcg cccgagatcc ccatcctcga cggcagctcc
    47281 gcccccttcg tgttcctgct ccagtcggcc ggcatcgagg agcagaaggc ggcgaagaag
    47341 ttcctgcgcg tgaagaagcc ggtcgagtac gtcgagggcg acaagtgggt gcggctcgag
    47401 ccccatgacg gcttccgcct agcgttctcg atcgtgttca accaccccgc gatcgacagc
    47461 acctcgaccc gggtcgaggt ggacttcgcc cgtcattcct atgtgcgcga cgtggcgcgc
    47521 gcgcgcacct tcggcttcat gcaggacgtc gagttcatgc aggcgaacgg cctggccctg
    47581 ggcggcagcc tcgagaacgc gatcgtcatg gacgagtacc gcgtgctcaa cgtcgagggc
    47641 ctgcgctacg ccgacgagtt cgtcaagcac aaggtgctgg acgcgatcgg cgacctctac
    47701 ctgtgcggcc accccctgct cgcgtcgtat tcggcgcaca aggccggcca cgcgctcaac
    47761 aaccagatcc tgcgcgtgct gctcgaggac aaggaggcct gggaactggt gagcttcgac
    47821 caggaggcgg cgactccgcc ggcggtctcg caccagttcg cgccgctcgc ggctgcgttc
    47881 gcatgagcct gcgttccgtg cgcgggagcg ttcgcgtgga cctgcgcgag gcgccccggc
    47941 ctgctcgtcc gcgcgaggtc gccgcggaga tcgcctaccg cgagaccccc gtattgcgac
    48001 tcgagaggcc gcacgcatgc tgatcatgcg tttgctcctg ctgctcgcgg tgctgtcgat
    48061 cggcggctcg gcgatcctgt ggctgctcac cggcaacccg cgctacaagg cctgggcctg
    48121 gaaggccttc cgcgccacgt tggtgatgct gttcgtgctg ttcgccctgt tcgccatcga
    48181 gcgcgtgctc gcgccggttg cctgacggcg acgaagcgcg accgcatggt agtcgcccat
    48241 tcgcggctgc cgccgctcct acagggggcg gaggcgcggc ggttcatgta ggagcgccgg
    48301 caggcgcgat ggcggcggcg ggggattggc acgcgtcgat caccgagcgg ccggattcgc
    48361 ggctgccgcc gctcctacag ggggcggagg cgcggcggtt catgtaggag cgccggcagg
    48421 cgcgaagatc ggcctcggag gcgtgcttca tgccgggacg cggacgggcg cgaacgcggc
    48481 gtgcaggaag gggcgtcgtc tcaggcgcgc cggatcaggc gctcgatcga cgcgcgcagc
    48541 ggcgagtcgg ccggcagggt gtcggcgaag tcgtgcaggt cggccttggc cgattccgag
    48601 atctgccttt gcggagccgg gcgctcgggc gccatctgct cgggcgtgcc caccttgacc
    48661 ttgatcgact gcaccgggtg accgccatgc tgcaggcgct ccagcaggct gggcaggatc
    48721 tgccgcaccc gtaccgccgc ggcgccgccg cgcgcggcca cgaccagact gccctccttg
    48781 aggttggcga cgcggcactg gccctgcagc tgcggcggca gcatgccgtc gagcaccgcc
    48841 tgcagccggt tgagccgcgc ggcatggtcc tgcaggcggg cgagcgcgtc gccgcctaga
    48901 aagcgtgaga gcggccgggt catgggtgct tgcgagaacc gtcacgggga gcctgggtgc
    48961 gccatgataa actcccgcct ttgccgaatc gacgtcgaac ccaaaacatg atctccggcc
    49021 tgctcaagaa aatcttcggt agtcgcaacg accgcctcgt ccgccagtac atgcacaccg
    49081 tgcgcaagat caacgccctc gaggccgaga tctccgcgct gtccgacgag gcgctgcgcg
    49141 gcaagaccgc ggagttccgc gagcgcgtgg ccaacggcga gtcgctcgac gcgctgctgc
    49201 ccgaagcctt cgccgtggtg cgcgaggctg gcaagcgggt gcacggcatg cgccacttcg
    49261 acgtccagct cgtcggcggc atggtgctgc acaacggcaa gatcgccgag atgcgcaccg
    49321 gcgagggcaa gacgctggtc gccacgctgc ccgcctacct caacgcgttg tcgggccgtg
    49381 gggtgcatgt gatcacggtg aacgactacc tcgccagccg cgacgccgag tggatgggcc
    49441 gcatctacgg cttcctcggg ctcaccaccg gctgcaacct gtcgcgcatg tcgcacgacc
    49501 agaagcaggc cgcctacgcc gccgacatca cctacggcac caacaacgag ttcggcttcg
    49561 attacctgcg cgacaacatg gtgtatgcgg tcggcgagcg cgtgcagcgc gcgctcaact
    49621 tcgcgatcgt cgacgaggtg gactccatcc tcatcgacga ggcgcgcacg ccgctgatca
    49681 tttccggcca ggccgaggac cacaccgagc tgtacctgaa gatgaaccag gtcgcgccca
    49741 tgctcaagcg ccaggagggc ggcctcgacg acaaggacga ggtcatcgag gcgggcgact
    49801 acacggtcga cctcaagtcg caccaggtgc tgctgaccga ggcgggccac gagaccgccg
    49861 agcagatcct cgtgcgcatg ggcctgctcg ccgagggcgg cgggctctac gaccccggca
    49921 acatcctgct ggtgcatcac ctctacgccg ccctgcgcgc ccacgccctc taccaccgcg
    49981 accagcagta cgtggtgcag aacggcgagg tcgtcatcgt cgacgagttc accggtcgcc
    50041 tgatgcccgg ccggcgctgg tccgacggcc tgcaccaggc ggtcgaggcc aaggaaggcg
    50101 tgcgcatcca ggccgagaac cagaccctgg cctcgatcac tttccagaat tacttccgca
    50161 tgtacggcaa gctcgccggc atgaccggca ccgccgacac cgaggccttc gagttccagc
    50221 agatctacgg cctcgagacc gtggtcatcc cgaccaaccg cccgacccgg cgcaaggacg
    50281 agaacgacaa ggtctaccgt accgccaacg agaagtggaa cgcggtgatc gaggacatcc
    50341 gcgcctgcgt cgagcgcggc cagccggtgc tggtcggcac cacctcgatc gagaccaacg
    50401 aattcctttc cggcgtgctg aagaaggcca agatcgagca ccaggtgctc aacgccaagc
    50461 agcacgacag cgaggcgcag atcgtcgccc aggcaggccg tcccggcatg gtcacgatcg
    50521 cgaccaacat ggccggtcgc ggcaccgaca tcgtgctcgg cggcaacatc gagaagccgg
    50581 ttgccgcggt acgcgacgac gccacgctcg accccgcgca gcgcgaggcg acgatcgtcg
    50641 cgctgcgcga ggcctggcag aaggtgcacg acgaggtgat cgccgctggc ggcctgcaca
    50701 tcatcggcac cgagcgccac gagtcgcgcc gcatcgacaa ccagctgcgc ggccgctccg
    50761 gccgccaggg cgacccgggc tcgagccgct tcttcctctc gctcgaggat ccgctgatga
    50821 agatcttcgc cggcgagcgc ctgaacgcga tcatggtgcg cctgaagatg cccgagggcg
    50881 aggcgatcga gcatgcgatg gtgacgcgct cgctcgaatc cgcgcagcgc aaggtcgagc
    50941 agcgcaactt cgacatccgc aagcagctgc tcgagtacga cgacgtcgcc aacgaccagc
    51001 gcaaggtcat ctatcagcag cgcaacgagc tgctcgagag cgaggacatc tccgacaccg
    51061 tgcgcgccat gcgccagggc gtgctgcacg acatcttccg ccgctatgtg ccggtcgaca
    51121 gcgtcgagga gcagtgggag ctgtccgccc tcgagcaggc gctgctcgcc gagtgccagc
    51181 tcaagctgtc ggtggccgag tgggtcaagg ccgagcccag cctggacgac gacgccatcc
    51241 tcgagcgctt ggtgcaggcc ggcgaggagg cctacgccgc caagaccgcg atcgtcgatc
    51301 ccgcggcctg gcatcagttc gagcgcaacg tgatgctgca gagcctcgac acccactggc
    51361 gcgaacacct cgccgcgctc gatcacctgc gccagggcat ccacctgcgc ggctatgcgc
    51421 agaagaaccc caagcaggag tacaagcgcg aggccttcga gctcttcgag accctgctcg
    51481 acaccgtgcg caccgacgtc accaagatcc tgatgacggt gcagatccgc accgaggcac
    51541 agctcgagga ggccgagacg ccgcagcagg tcgagaacgt gcagtaccgc cacgccgact
    51601 acgacgaggc ccttggcggc gacgcggagc aggcgggcgc gcagccggcc gctgccggcc
    51661 ccaaggtcgg ccgcaacgat ccctgcccct gcggctcggg caagaagtac aagcactgcc
    51721 acggcaaact gaactgaccc ttccgccccg gagaaccgca tggccgttaa tctcgccacc
    51781 ccgaaccccg ccgaactgct gcccgtgagg ggcgtgcgcc tgggcgtgac cgaagccggc
    51841 atccgcaagg ccaaccggcg cgacctcacc gtgatcgagc tggccgaggg cagccgcgtc
    51901 gccggcgtgt tcacgcagaa ccgcttctgt gccgccccgg tgcaggtgtg tcgccggcat
    51961 ctggcgggcg gcgcgatccg cgcgctgctg atcaacaccg gcgtcgccaa cgccggcacc
    52021 ggtgagcccg gcctggccaa cgccaacgcc tgctgcgccg cactcgcgag cgcgatgggc
    52081 atcgaggccg ggcaggtgct gccgttttcg accggcgtga tcctcgagcc gctgccggtc
    52141 gaccgcgtgg tcgccggctt gccgggggcg gtcgccaacc tgcgcgccga cggctggttc
    52201 gacgccgcgc acgcgatcat gaccaccgac accctcgcca aggcggtgtc gcgccaggtc
    52261 cgcatcggcg agcgcatggt cactttgacc ggcatcagca agggcgccgg catgatcaag
    52321 cccaacatgg ccaccatgct cggcttcctc gcctgcgacg cggcgatctc gcaggacctg
    52381 ctcgacggcc tcgtgcgcga ggccgccgac ctgtccttca acagcatcac cgtcgatggc
    52441 gacacctcca ccaacgactc cttcatcctc atcgccaccg gcggcgccgg caatgccgag
    52501 atttccgctg ccgacagcga ggactaccgt gccctgcgcg cagcggtgat cgaggtcgcg
    52561 gtcgggctcg cgcaggcgat cgtgcgcgac ggcgagggcg cgaccaagtt catgacgatc
    52621 gcggtcgagg gcggccgcga ccgcgaggaa tgtcgcaagg tgggctacgc ggtggcgcac
    52681 tctccgctgg tcaagaccgc cttcttcgcc tccgacccca acctcggccg catcctcgcg
    52741 gcgatcggct acgccggcat cgacgacctc gatgtcgcca agctgcgcgt ctggctgggc
    52801 aaccccgagg agtcggtgct ggtcgccgag cacggcgggc gcgctgcgag ctacctcgag
    52861 gaggcgggct cgcgcatcat gaagcacgcc gagctcaccg tgcgcatcgc gctcgcccgc
    52921 ggcgacgccg ccgccacggt gtggacctgc gacttctcct acgactacgt gaagatcaac
    52981 gccgactatc gcagctgagc ggctcccggc aggcgccatg gccccggccg ccacgtggcg
    53041 ccggggccgt agcgcgtggg ggagcggcgg aacgccatgt gaggctacgc gtgacgtggt
    53101 tcacctgtgg caggtcatcg gtcttgttgc cgcccccaca atgggcagaa ttcaatccgg
    53161 gtggcgcgtt caggtcgcca tggagccgcg ggaatcacca cgtcatgcag gaaaagttcg
    53221 ccctttgccg tccgcgcgcg cggagcctgg cctcgcgtgc cgggccggtg ttgctgctcg
    53281 gcctgctggc gctcgatgca cgcgcggaaa ggggcgaagc ggatcccttc ttcggcgcga
    53341 tccccatggt gttgaccgca tcgcgcctgg cgcagtcgcc gctcgacgcg ccggcgccgg
    53401 tgaccgtgat cgaccgcgag atgatcgtcg cctcgggctt caacgagatc cacgacctgc
    53461 tgcgcctggc gccgggcttc ctcgtggccg accatcccga cgggccgccg gcggtcgcga
    53521 gccacggcct cggcgacgcc catgcgcggc gtatcaaggt gatggtggac gggcgcacga
    53581 tcaacagccc gctatggggc aacgtgatct gggacaacct gccgctgcgg gtggacgacg
    53641 tcgagcgcat cgaggtggtg cggggtccca atggggcggc gtacggcgtg aatgccttcc
    53701 agggggtggt caacatcatc acgagggcgc cttcgacgga gagcgggagg gcgttcgtcg
    53761 tgcgcgccgg aaagaacggt ttccgtgatt acggcgtgcg cctgaacggg gcaggcggaa
    53821 gcgccttcga ctggcggctc tccgcctcgc ggcgcgaact tacaacgttc gagccgcact
    53881 ttcggcagcg gctcggggac tggcactctt ccgagtcgct tactcgcaac acggctcact
    53941 tcagctcggt actgcaggtc tcgaccctgg atgagctcgg cttccaggtc ggcgtcagtg
    54001 agggccgcag caagcgcggt gccgaggcct acctcgacta cccccggcac gccgaggacg
    54061 accgcgcgct ccacctgcag gcgggctggc ggcgccaggt cgacgccgag tccgtgttga
    54121 gcctgcagta ttttcatcag gccgagcgcg cccgcgggaa ttgggcggtc acgcagcgac
    54181 acccgacgga cccggccatg gtcgtgcgct ttccctccag tcgtgacagc gaggcgcgcc
    54241 ggcacgatct cgaactgcaa tacgacaccc ggctcgctcg ccgtctcacc ggcatgctcg
    54301 gcatcgggct gcgcagcgag catgcacgct cgacgcacct gttcggcacg ggacggtggc
    54361 tggatgcgac gcatgggcag atcttcggca gcctcacgtg gaatccgctc gagccgctca
    54421 agatcgacct cggcggcacg ctcgaacacc acgactacag cggccggctg ttctcgccgc
    54481 ggcttgcgat gaactacgcg ctcgacgcgg actcggcgct gcggctgtcg accggtacgg
    54541 cctaccgtgc gcccagcctg atggagtcgc gcgccttcca gaccgaccgc gagggcgaca
    54601 cgatccggcg tatcggcttc cgtgtgttcg agccgctgca gagcgagcgc atgcgcttcg
    54661 tcgacctggg ctatgtcgcg cagctgcgtc cgctcggcct gaacctggac gcacggatct
    54721 tccgcgagca ttaccgccgc ttcatcgacg acaagagttg catcttcggc gagtgtccgg
    54781 gtacggagcc ggccgcctac gtgcccatcg acccgggcaa gaagagcttc tatttcctca
    54841 acgcgagcga cttccgcatg accggtgcgg aattcaccct cgactggcgc aagctgggct
    54901 ggggcagggc ggtgctgtcc caggccttca tccgtatcga tcatggcgag ccctacagcg
    54961 accgcgacat cccgaacagc gcgccgcact cgacaacgtc gctgctgctg atcaaggact
    55021 tgcccgggcg ctggcaggcc agcctaggct attaccacaa cggcctctac tactggatga
    55081 acggtggcga catcgtgccg cgcatcgacc gcttcgacct gcgcatcgcg cgccgcttcg
    55141 gcccgcccgg atcggacaac gaggtctcgc tcaccgcgct gagtctcaag gggcgctacg
    55201 ccgacttcca tgaggacaag ttccgccacg aacccgacct ctatctcggc gtgcgcatcg
    55261 gatggtgaca tcggtgattc gagcgctcgt gtcgcgcctc ctgcctggct gccagcgtgt
    55321 ggcgctggtg ctcgccatgc tcggcttgct gcccggcccc gatggttttt cggtgcaggc
    55381 gcaggccatg gaggtggccg tgctgctctc ggaggcggag ggccgcggcc agcgctttgc
    55441 cgaggcactc gatgccgcgc tcgcacccgg gatgcatcgg ctggtcgccg ccggggtggc
    55501 cggtgtccag gccgatgcgg cgctgctcgg tcgcgccgac ctggtactcg cagtgggcca
    55561 ggccgctgcc gagcacgcat tgcgtgcgtc cgcacagccg gtgctggccg tgctcgtggg
    55621 gttgcgagac gtcgatcgcc tgaacggcgc gcatccgggg cgcggactgg gcgcgctggt
    55681 gctcgatcag ccgctggagc gccaccttcg gctcgttcgt gcggtccttc cagacgcgaa
    55741 gcgcgtcggg gtgctgctcg ggccggacag cgtcttgcaa ctgcccgggc tccccggcgc
    55801 agccgacgcg tgccagctcc aggccgatgt gcatgaggtg cgccagcccg cggatctcgt
    55861 ccccgcgctc gaccaccttc tctttgcggg tgacgccctg ctcccgctac ccgatggcct
    55921 ggtgtccggc cccgcggcgg cgcgcacgat cctgctcacc agctaccgcc accgccgccc
    55981 ggtgttcgcc cactccgccg cctacgtcac cgcgggcgcg ctcgccgcgg tgttcagcac
    56041 gcccgagcac gtcgcaatgg atgtggccga cctgctggca ggggctgcgg agccgtcggc
    56101 catggtgcgc aagatccacc cgccgcggcg cttcgacgtc gccgtcaatc gggcggtggc
    56161 gcgtgcgctg gggcttgtgg ttgcggatga gaaggcactg cgcgagcgta tcgccaacgg
    56221 gggcgagcaa tgatcggcgc gctcgcccgt tgctcgctgc ggcggcagat gttgctggtg
    56281 ctcggcctgc cgagcgtgat cctcgtgctc tgcatcgctg cgctcttcgc ctaccagagc
    56341 agccgtgcgc tcgaccaggc cctgctcgaa cgtggccggg ccatggtgcg cttccttgcg
    56401 ccggcggccg agtacgtgct cgtctcgggc aaccgcgagg cactcgccgc actgatggcg
    56461 cgggtgcagg cgcagcccga cgtgatcggg gtcggattct acgatcccgc tggcgaagtg
    56521 ctggtgatgc gcggggaggg cgtgtcgccg cggctggctg caccggtccg cgaggacggc
    56581 gacgagatcc gcgtcgcact cgcagatgcc gcgatcggct tcgaggcgcc ggtggtggtg
    56641 gtgcctgcgg cggtggatga ctatgccacg agaccggccg cgaagacggt ggaggtgatc
    56701 ggtggggtcc gcgtggtgct gggtactgcg cgcctcgatg ccgagaagcg tgccgtcttc
    56761 ctgaccgtga gtgccctggt gctgggcgtg ctctcggcgg cgatggtggt cgcggtcagg
    56821 ctcgccggct cggtcggaga gccggttgcg gcgctggtgg acgcggtcgg ccgcatggcc
    56881 gacggcgatc tggccgtgcg cgtgccggcg cgtgcgcgca atggcgagct gaaggcgctt
    56941 gaggccggct tcaacgccat ggccgaggcg atcgccgaga accagcgcac cctgcaggcc
    57001 cgtgtcgacg aagcgaccgt gcagctggcc tggcaggccc gccacgatcc gctcactggc
    57061 ctggccaacc ggcgcgcctt cgaggagcgc atcgagcagg cggtgcgcgc gcaccgccgc
    57121 tcgggcgacc agatcacgct cttctacatc gacctggacc acttcaaggc ggtcaacgac
    57181 agctgcggcc atgccgcggg cgacaagctg cttggtgaac ttggcgtgct gctcaagggc
    57241 cgcctgcgcg ccgaggacga ggtcttccgc atcggcggcg acgagtttgc cgcgatcctg
    57301 cgcggctgcg gcagcgagga cgcgcgccgg atcgccgagg gcttgtgcac ggcgatcgct
    57361 gcccatgcat tcgagtgcga gggccggacc ttccgtgtcg gcgccagcat cggagtggcg
    57421 cgcatggacc cggagctgca ggaggtcgac gcgctgatga tcgccgccga ccaggcctgc
    57481 tacgcagcca agcacggcgg ccgcggacac gtcgtggagt atccgctgcc cgcgccagcg
    57541 tcgtgacgtg tccgtcgctc agtgcagcgc cttcggcacc gcaagcatga aggcggggat
    57601 ctccgcctcg aactcgtggc cgtcgtcggc gcgcatgcga tagctgccct gcatcgtccc
    57661 caccggcgtg gcgagtacgc agccgctggt gtagcggaag gcctggccag ggccgagcac
    57721 cggctgctcg ccgaccacgc cctggccatg gacctcctgc atcttgccgt tgccgtcggt
    57781 gatcacccag tggcgtgcga gcagctgcga gcgcacgctg ccggtgttga gcacggtgat
    57841 gtggtaggcg aacacgaaat ggtcgtcctg cgggcgcgac tgctcggcga cgtattcggc
    57901 gaccgcggtc acctggacgc ggtaaggcgt ggattcgctc atagtctggt gttctcgtcg
    57961 tttgttctcg gccggcaagt agggcaggcg ttaaaataac agtttttccc ggaagctccc
    58021 gccatgtcga acgccgcacc gtctccgctc accgccctct ccccgctcga tggtcgctac
    58081 cacggcaagg tcgccggcct gcgcgagcac ttctcggaac acggtctgat ccgcaaccgc
    58141 gtcaaggtcg aggtcgagtg gctcaaggcg ctcgccgccg agcccgcgct ggcggagatc
    58201 gcgcccttct cggcggcgac cgtggccgag ctcgacgccg tggtggcgaa cttctcgacc
    58261 gaggacggcg aggcggtgaa ggcgatcgag gccaccacca accacgacgt caaggccatg
    58321 gaatactggc tcaagaagcg cctcggccac aacgccgagg tgatgaaggt gtccgagttc
    58381 atccacttcg cctgcacctc ggaagacatc aacaacacct cgcacgcgct gatgctggcc
    58441 gaaggccgcg accgcgtgct gctgccggcg ctcgatgccg tcatcgcgcg cttccgcgaa
    58501 ctggcgcatg cgctcgccga cctgccgatg ctgtcgcgca cccacggcca gcccgccagc
    58561 ccgaccacgc tcggcaagga gatggccaac atcgccgcgc gcctgatgcg cgcccgcgcg
    58621 gcgatcgccg gcgtcgccat gtgcgccaag ttcaacggcg cagtaggcaa ctacaacgcg
    58681 cacctgtcgg cctggccggc gttcgactgg gagggcttca accgccgctt catcgaatcg
    58741 ctcggcctga ccttcaacga atacaccatc cagatcgagc cgcacgatgc catggccgag
    58801 ctgttcgacg cggtcgcgcg cgccaacacc atgctgatcg acgcctgccg cgacatctgg
    58861 atgtacatct cgctcggcta cttcaagcag aagctgaagg aaggcgaggt cggctcctcg
    58921 accatgccgc acaaggtcaa cccgatcgac ttcgagaacg ccgagggcaa cttcggcctc
    58981 gccaacgcgg tgctcaagca cttctccgag aagctgccga tctcgcgcat gcagcgcgac
    59041 ctcaccgact ccaccgtgct gcgcaacatg ggcgtgggct tcggccacac cgtgctcgcg
    59101 ctcgacagct gcctgcgcgg tctgggcaag ctcgaggccg acccggcgcg cctggtggcc
    59161 gatctggacg agtgctggga ggtgctcgcc gagccggtgc agacggtgat gcgccgctac
    59221 ggcatcgaga acccctacga gcagctcaag gcgatgaccc gcggcaaggg catcacgcgc
    59281 gaggccctgc aggagttcat ccgcacgctg gcgatgcccg ccgaggcgcg cgaccacctg
    59341 ctggcgatga cgccggcgag ctacgtcggc aaggccgccg aactcgcccg ccgcatctga
    59401 gcattgcgcg aatccgccgg ccgcgcgccg gtgcccatcc cgacgccacc cttgcggtgg
    59461 cgttttccat ccaggagaaa ccccatggcc ttcgccgaca atctcaagac cctgcccggc
    59521 gtgtcccacc tcgccgcgct caacctgatc gacgccgccg atacggtcgt cgccaccatc
    59581 gagaacaagc ctggccaggc cggctcgctc gcggtctaca accacctcgc ccagctctac
    59641 ggcgcgatca gccccgaggc agccaggaag ggcctggagc tctacgccga gcacaccgag
    59701 gatgcccgca cgaaccctgg caagcacccc aacatcgacc gtttgatcgg cttgatcgag
    59761 cgcggcgaga cgctgcgggt gaagcaggtg tttgcgattt gatgtgtggg gcggcgtgat
    59821 cgtttgcgtc ccgccgatcc ggctgcgatc cggtcgcggg accggggcgg cgctcgccgc
    59881 ctgcactcgc ggcccttcgc ttcgctgcgg gctgccctcg gtgggggacg ccgcgggggc
    59941 ggcaacgcaa actcggcgct gcgcgcctca gacatgcgtc gccttgattc ccccgcgacg
    60001 tcctccacct cggcgctcct gaagttggcg ggcgccgccc cggccccgcg acctcacgtt
    60061 ggcgcttcct ggccggccga ttccgctgcc gggcgttgat gcatccgtgg ggggcgaagt
    60121 gggtgccgat cacgtttttc gcgccacgaa cagcgccgta tcgacggtga aactgctgtc
    60181 ctcctccatc tcgaaatagt ccttcaccgc cgacgcggct cttgcctgga gcatccggat
    60241 cgctgtgacc tgcggttcgg gcgtgtccat gcgtgcgacc caggttgcga agtcgaggcg
    60301 aagccgaaga tgctcgatgc gctcgatcgc caatccggcg gccgcgagtg cggcatccca
    60361 ctctgccgtc gaggcgtcgc gcacatggga ggggtcccgc agtagttcga gcgtttgcag
    60421 ccaggtgtcg agaagggaga cgccgggcga caccacatcg gacatcagcg cgagcccgcc
    60481 cggcttgagc acgcgtgcca tctcggcaat accctcggcg aaggcatgcc agtggtgcgc
    60541 gctgaatcgg gtcgcgacca cgtcgaaagt cgcgacctcg aaaggaaggg attcggccgc
    60601 ggcctcgcgg gtggcgatgt tgggcaggcc gcgcaagctg gcctgctcgg cgaccgccgc
    60661 gagcatggat gcggcaaggt cgcaggccac gacctggctg acgagcgggg cgaggcggta
    60721 tgtgaggtgt cccccaccgc aaccgacgtc gagtgcgact gcaccgcgct ggttggcgag
    60781 gagctgcgcg atgaggtcca gatcctgcca tgcggcgtgc gcagcgctgt tcacataggc
    60841 actggcgcga gtggcgtatt ggtccaggac aactgagttg tggctggcgg tctgcatggc
    60901 gggctcctga agtgagggcc ttcagtgttt tccatgcaat ctactggtac aagatgcctg
    60961 gttatcctgg tataaaacct gccatgaatc cctctgaagc ccgccgcctg ctcggtgcgt
    61021 tcatccgtgc ccaccgcgaa cgcctgtctc caccggccaa agcccttggc cgccgccgca
    61081 cgccgggttg gcgccgcgaa gagttggcgg atgctgcagg gctgggcgtg acctggatca
    61141 cctggctcga gcaggggcgc gccgtaaatg cttctgtgcc cgcgctgtgc cggctggccg
    61201 aggcgctgca actcaccccg gccgagcgca tgtcgctctt cgaccttgcc ggaaagcgcg
    61261 atccgttggc gagccacgcg ccgacgacgg acctgccggc ggaactcctt tgcttgcccg
    61321 gccacgtttc cgcgcctgcg tacctgctgg acgcaagtta tgccgcgatc gcctggaacg
    61381 atcaagctgg cgagctattc gtgggctggc tggacacag
//
LOCUS       DAOTIN010000008        57539 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_525_length_57539_cov_9.138873, whole genome shotgun sequence.
ACCESSION   DAOTIN010000008 DAOTIN010000000
VERSION     DAOTIN010000008.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 57539)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 57539)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57539
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_525_length_57539_cov_9.138873"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1047)
                     /locus_tag="P5537_02290"
     CDS             complement(<1..1047)
                     /locus_tag="P5537_02290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2169 domain-containing protein"
                     /protein_id="HRV76903.1"
                     /translation="MELINATRMLAGYTMGIEPSGRELLVVVIKGTFHLPRNGEEVRL
                     HEEQLPLVMADTFTGEPGFSAPMYEADFAPRKPCCDVLLLGSAYAPDGRPLTRVPVGL
                     RVGNMTKRFAVVGDRHWEVGLGRISASPPEPFVIKPIAYDVAFGGVDNEHEDFAKHGA
                     CMRNPVGRGYRLQLKSEWVDGKPLPNTEELNRPVDRPDGDFAPMAFGPIGRNWEPRYR
                     YAGTYDQDWLDKVFPFLPADFDERYYLSAPPDQQLAIPIGGPEVTLINLTADGRRSFT
                     LPDFEAPVHVFPKKGEREDYKAMLDTIVFEPDQERLTMTWRVARPLKKNMFEIAQVLV
                     GKKGKEWWQKREEVA"
     gene            complement(1073..1630)
                     /locus_tag="P5537_02295"
     CDS             complement(1073..1630)
                     /locus_tag="P5537_02295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6484 domain-containing protein"
                     /protein_id="HRV76904.1"
                     /translation="MEKTMSGRDPIEGSSLPKATFRDGAELLQPLLEGASAVTSAPQR
                     VDGVLVGELVAIADEGRTPLVLYPGQPGTAAIGARSTVDLHGAHIGKRMVLMFEGGDP
                     LRPIVMGVLRQGEGWPLEERPGQVELDVDGERMTVSAREQLVLRCGKASVTLTKSGKV
                     LIQGTYVSSRSSGVNRVKGGSIQLN"
     gene            complement(1630..3843)
                     /gene="tssI"
                     /locus_tag="P5537_02300"
     CDS             complement(1630..3843)
                     /gene="tssI"
                     /locus_tag="P5537_02300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tip protein TssI/VgrG"
                     /protein_id="HRV76905.1"
                     /translation="MPRVMEITTPLGDGVLLFHAISTREELGRLFEYQIDVLSERNDI
                     DPNKLLGHNVTVRVELPDGGERHFDAYVTAFSLVGVLGRYLRYRIVGRPWLWFLTRCA
                     DCRIFQNQKVPEIIAEIFGKYSIAAYELDRLTGTYEPWEYCVQYRETDFNFVSRLMEQ
                     QGIYYYFTHKDGKHTAVLCDSPSAHEPYPGYAQLPFVSGERALRIERERITEWGFSWE
                     VQPGAYAIDDFDFKKPSVELLQQTRHKRDYAEAEHEIYDYPGEYDSKGEGEAYVRIRL
                     EELQSQVQIMQGAGNARGIATGCVFELEEQPREDQNRKYLITASRLDFVLAAHEAGGG
                     EGASFRSSFDCIASDLPFRTQRTTRKPLVQGLQTAIVVGPAGDEIYTDEYGRVKVHFQ
                     WDRHGKDDENASCWIRVSHPWAGKNFGMVAMPRIGQEVVVEFLEGDPDRPLITGRVYN
                     AEQMPPWELPANKTQTGVLTRSSLGGSGANANAIRFEDKKGSEQLWIHAEKNQDIEVE
                     NDETHWVGHDRMKTIDNDETTHVKHDRTETVDNNETITIHGQRTETVDKDETITIHQN
                     RSERVDIDEKISIGANRSEDVGVNESITIGSDRSVTVGANETKTVALQRTHTVGVNET
                     IAIGAAQEVAIGAFQSVNVGANLSTSVGADESRDVGGGRGTNVGKDDSLKVGKNLVID
                     AGDSVTIKTGSASISMKKDGTITIKGKDITIEGSGKINVKAGANVVMKGSKILQN"
     gene            complement(3943..5319)
                     /locus_tag="P5537_02305"
     CDS             complement(3943..5319)
                     /locus_tag="P5537_02305"
                     /inference="COORDINATES: protein motif:HMM:NF024880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HRV76906.1"
                     /translation="MSSAPSAPAATAGEAPMSVDEALGHALRLHRAGYLDPAEKIYRA
                     ILGLCPDEAEVLHLLGMLRHARGDSAEASALIRRALALVPDAPGAWNNLGNVLLESGS
                     VDDAIAAYRRCLELMPDFAEAHNNLGTIHRSRSEWSLAEEAYQRALQLAQARVEAGEP
                     AELLADVHNNLAGLMLARGRLRAAVDHACRAITASPGQVGARKLLGLAYYTLGEFDKA
                     ADVYRSWLADEPDNPIARHHLAACTGEAVPARAADDYVERTFDAFASSFDEKLQRLHY
                     RAPMQVAQALEEAYGAPAATLDVLDAGCGTGLCGPLVRAHARRLEGVDLSAQMLQRAE
                     RRGVYDQLHKAELGAFLAARPAAWDVVLSADTLCYFGDLGAVLAAAHGALRRGGRLFF
                     TVEAVGDEDAGPPFILQPNGRYAHTRNHVVAALVAAGFEAALPSAQVLRTEGGEPVAG
                     WLVGACKP"
     gene            complement(5316..8210)
                     /gene="tssH"
                     /locus_tag="P5537_02310"
     CDS             complement(5316..8210)
                     /gene="tssH"
                     /locus_tag="P5537_02310"
                     /inference="COORDINATES: protein motif:HMM:TIGR03345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0033104 - type VI protein secretion
                     system complex [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system ATPase TssH"
                     /protein_id="HRV76907.1"
                     /translation="MSEISRMALFGKLNRVAYKAIEGATVFCKLRGNPYVELEHWVMQ
                     IVQAQDSDWHRIIKHYQVDMAVLARDITTALDRLPRGATSITDLSENITNAIERGWVY
                     GSLMFGDNAVRTGYLLLGMLKTTYLRNALYAISRQFERIRAEDLSEALVQVVSGSPED
                     LLGEASGSTAEPGEASGAMAPAALGKQEALHKFAIDLTEKARKGEVDPVRGRDEEIRQ
                     IVDILMRRRQNNPIITGEAGVGKTAVVEGFAQRIVQGDVPPLLQGVKLLTLDIGLLQA
                     GASMKGEFEQRLRQVIDEVQASPKPIILFIDEIHTLIGAGGTAGTGDAANLLKPALAR
                     GNLRTIGATTWAEYKKYIEKDPALTRRFQMIQVQEPDEAKATLMLRGVATVLEKHHRV
                     QLLDEAMEAAVRLSHRYIPARQLPDKAVSLLDTACARVAVSQHATPAEVEDCRRRIEA
                     LDTELEIIGREELVGIEIGTRRGDAEARRAQELARLGELEARWKEEKGLVDQILELRG
                     KLRAGGERVDHPPADVEPAAPELAASTPPSGDAGELAAQAPPADASAPADAPAAALEP
                     APAAPAATAAGGADEAGAAAVQPPAEDRAALLEQLKTLQEHLRGLQGETPLIMPTVDE
                     QSVASVVADWTGIPVGRMVKNEIEAVLHLADTLEQRIIGQRHALEMIARRIQTSRARL
                     DNPNKPIGVFMLAGSSGVGKTETALALAEALYGGEQNVITINMSEYQEAHTVSTLKGA
                     PPGYVGYGEGGVLTEAVRRRPYSVVLLDEMEKAHPDVHELFFQVFDKGWMEDGEGRVI
                     SFKNTLILITTNVGTDLIMGLCKDPELLPDPEGIARALREPLLKVFPPALLGRLVVIP
                     YYPLTDAIIGLIARLQLKRIGRRIHDNHKIEFSFDEEVVKLIIGRCTEVESGARMIDA
                     LLTNTLLPRISQEFLTRMVEGRAVDRVQVGVAEGDFRLSFDAAPAGGEAG"
     gene            complement(8236..9276)
                     /gene="tssG"
                     /locus_tag="P5537_02315"
     CDS             complement(8236..9276)
                     /gene="tssG"
                     /locus_tag="P5537_02315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004360577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssG"
                     /protein_id="HRV76908.1"
                     /translation="MRESADRLAFLRALEQKPYAYDFYQTLRRIECLFADKPRLGQAL
                     RPADEPVRLAQEASMSFAPAPIAAFRPAEDARPPELVQRIFGLLGPNGPLPLHLTDYA
                     RERQLHHGDATFASFLDLFHHRLLALFYRGWAQAQPDVSLDRPAQDRFAMYVGALLGI
                     GPDRLRGRDAAGDRVKLFHSGLFARQVRNGDGLQAILADYFGVAARVESFVGHWMRLP
                     EAERTRLGSGSMGARLGFGVVLGARVWDRQHQFRIRLGPMGLADYEAFLPGGQSLPRL
                     LALVRQYLCFELDWDVRLVLRRPEVPALRLGGGQRLGWTSWLGRPRGEDDPAPLALHA
                     EDALARRARKVN"
     gene            complement(9252..11129)
                     /gene="tssF"
                     /locus_tag="P5537_02320"
     CDS             complement(9252..11129)
                     /gene="tssF"
                     /locus_tag="P5537_02320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004360575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssF"
                     /protein_id="HRV76909.1"
                     /translation="MDPRLLRYYDQELRHVREMGAEFAAQFPKVAARLGMHGIEVADP
                     YVERLLEGFAFLAARVQLKLDAEFPRFTQRMLEIVYPQFLAPTPAMVIAQFQPDIQDA
                     NLARGFRIPRGSTMHGTVARGETTACEFRTAHEVCLLPLEVVAASYFSFAPDLPLQQL
                     PDGRRVKGGLRIRLRSGAGLGIADLELARLPIHLGGVDEVAFKLYELALGACVGMLVQ
                     PVGEGASSSRFVPASEVRALGFEDDEALLPVNLRGFQGYRLFHEYAAFPQRFCFIDLH
                     GLGAPARACRGSELEIVLLFSRGDPTLEGVVDAANLRLFCAPAINLLERNADRIHVGD
                     GSHDYHVVVDRTRPIDFEVHAIESVTGFGSGGVQAQREFLPLYAAFHHESAQHAAYFC
                     QQREPRLLTEEQKRRGTRTSYVGSEVFISLVDPEEAPYSDELRQLSVRVLCTNRDLPL
                     QMPIGLGKTDFTLDSAAPVSAVRVIKGPTRPVSALREGSVAWQFISHLSLNYLSLSHG
                     DAGDAAAAMREMLELYALAGDGAVVRQVEGLRALRVNPVVRRFPLPGPVSFGRGLEVE
                     LEIDEMAFQGGSAFLFGAVMERFLGRYVSINSFVETVLRASGRGEIMRWVPRCGNRPI
                     V"
     gene            complement(11133..11639)
                     /gene="tssE"
                     /locus_tag="P5537_02325"
     CDS             complement(11133..11639)
                     /gene="tssE"
                     /locus_tag="P5537_02325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011767622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssE"
                     /protein_id="HRV76910.1"
                     /translation="MADSVPKDRLQPALLDRLTDDEPDRALEPRAERLISRQHMRQSV
                     LRDLGWLFNATRAADADDWPGAPLALRSVVNFGLPALAGETASTLDVIQLERAMRQAI
                     LEFEPRIDPGSLKLRALAEQIALDRHNRIEVEIRGSLWAQPTPIELLLRTNVDLETGQ
                     IEIQDLGR"
     gene            complement(11632..12453)
                     /locus_tag="P5537_02330"
     CDS             complement(11632..12453)
                     /locus_tag="P5537_02330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004360571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system accessory protein TagJ"
                     /protein_id="HRV76911.1"
                     /translation="MITDAENAVRAGDLPLALDRLQDAIRAKPEDVRLRVFLFQLLCV
                     LGRWERALSQLEVCAEMDAAAIAMRETYRDAIACERVRADVFAGIRSPMLFGEPETWI
                     ALLIESLLRAGRGEEEAGERLRQQAFELAPTTSGSVDGKAFAWIADCDMRLGPVLEAI
                     VNGRYYWIPFCRLARIDLEEPTDLRDSVWLPAHLRFINGGESVALIPVRYPGSESVDD
                     GLIALARKSVWSESRSGVFCGLGQRVLATDVGEYPLLDIRQVRLGEDAEIAPDHG"
     gene            complement(12502..12984)
                     /locus_tag="P5537_02335"
     CDS             complement(12502..12984)
                     /locus_tag="P5537_02335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004360568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tube protein Hcp"
                     /protein_id="HRV76912.1"
                     /translation="MAKSDMFLKVEGARSGTIKGESEDAERKGEIDVVSWSWGMHAQT
                     EMGGGGSLAKASMREFLISKRVDSASTPLMAALRNNDLIKKATLTVRKAGKAPLDYYI
                     VVMEQGRITSLDVESVGEEHPELVERLSFSFQKISIEYVPQGPDGLGMGSMLFEAETI
                     "
     gene            complement(13064..13546)
                     /locus_tag="P5537_02340"
     CDS             complement(13064..13546)
                     /locus_tag="P5537_02340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004360566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tube protein Hcp"
                     /protein_id="HRV76913.1"
                     /translation="MAVDMFIKIGDIQGESADGKHAKEIDVLSWSWGMSQSGTTHTGG
                     GGGSGKVSVQDINFVKYVDASTHALIKACCDGSHFKEAKITVRKAGKEALEYIKLTMK
                     EVIVTSVATGGSGGEDRLTESISLNFAEFKLEYTPQKEDGTGDSAKEVAWSIAKNQPA
                     "
     gene            complement(13622..15112)
                     /gene="tssC"
                     /locus_tag="P5537_02345"
     CDS             complement(13622..15112)
                     /gene="tssC"
                     /locus_tag="P5537_02345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011767618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0033104 - type VI protein secretion
                     system complex [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system contractile sheath
                     large subunit"
                     /protein_id="HRV76914.1"
                     /translation="MAEVQQSTQLAGVALEGDELASLLQKEFKPKTDEARSAVEQAVL
                     TLAQQALANTTVISPDVVKSIEAIIAELDRKLTEQVNVILHHPDFQKLEGAWRGLHYL
                     VNNTETDEMLKIRVMNISKADLGKTLKKFKGTAWDQSPVFKKIYEEEYGQFGGEPFGC
                     LMGDYYFDQSPPDVELLGEIAKVSAAAHSPFIAGASPTLMQMDSWQELANPRDLTKIF
                     LTPEYAAWRSLRESDDARYIGLAMPRFLARLPYGAKTSPVDAFDFEEDTGAADHSRYT
                     WANAAYAMAVNINRSFKLYGWCSRIRGIESGGAVEGLPVHTFPTDDGGVDMKCPTEIA
                     ISDRREAELAKNGFMPIVHRKNSDFAAFIGAQSLQKPFEYDDPDATANANLAARLPYL
                     FACCRFAHYLKCIVRDKVGSFKEREDMQRWLQKWIMNYVDGDPAHSSEQTKARKPLAA
                     AEVVVEEVEGNPGYYTSKFFLRPHYQLEGLTVSLRLVSKLPSAKAA"
     gene            complement(15145..15672)
                     /gene="tssB"
                     /locus_tag="P5537_02350"
     CDS             complement(15145..15672)
                     /gene="tssB"
                     /locus_tag="P5537_02350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004360562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system contractile sheath
                     small subunit"
                     /protein_id="HRV76915.1"
                     /translation="MVTSSQKFIARNRAPRVQIEYDVELYGAEKKIQLPFVMGVLSDL
                     SGKPAEPLPKVDERKFLEIDVDNFDSRMKAMKPRVAFQVPNTLTGEGNLNVEITFESM
                     DDFSPAAVAGKVDALNKLLEARQQLANLITFMDGKSGAEELIAKVIQDPALLQSLAAA
                     PKPADEGKPAEGGGA"
     gene            complement(15724..16827)
                     /gene="tssA"
                     /locus_tag="P5537_02355"
     CDS             complement(15724..16827)
                     /gene="tssA"
                     /locus_tag="P5537_02355"
                     /inference="COORDINATES: protein motif:HMM:TIGR03363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system protein TssA"
                     /protein_id="HRV76916.1"
                     /translation="MNAIRAAISEPFGRRLPPLLPEDLLIDPDALLAETPELPPCGPD
                     LEYDPAFQALEEAARERIAQQYGDTVIPAQEPRWPEVRATAEGLLLRSKDLRVAVLLA
                     RALVKTEGFSALEYGLEIIRGLIERYWDALHPRLDPDDDFDPIVRSNALAPLVDAGAL
                     LKDLRASMVLPVRFGGGLKVRDVEVAAGKMPARPDEQAFSQAQVDRMFADAVLDDPGI
                     AAGVGKTLASARALAAALVERVGADRAVDFAPLLGLLGLVQQVCARVAPAPAQATQAG
                     AGGAERGVDADRLAPQTEEGMSGEIRNRDDALRMLDTVIEYFERNEPTNPAPLLIRRA
                     RRLVSMNFVDIIRDMAPESLKQIESIAGAEQKD"
     gene            complement(16799..>17609)
                     /locus_tag="P5537_02360"
     CDS             complement(16799..>17609)
                     /locus_tag="P5537_02360"
                     /inference="COORDINATES: protein motif:HMM:NF037085.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MBG domain-containing protein"
                     /protein_id="HRV76917.1"
                     /translation="LSAGNYLIESASSNAQALSIDPATLLVTVDPVSRLYGAANPAFS
                     ATVSGFLFEDSLANATTGTLALATPATERSAVGRYAVTASGLSAGNYLIESASSNAQA
                     LAIDPATLTYVATPATRPYSVPNPPLSGSVSGFVVGDTLETATSGVLVFASPAGQFSP
                     PGAYPIEGSGLSAQNYRFEQALENLVALTVTARAPGPEQGAVLRPTGESSRVHERNFG
                     LPPMCFAGGPLIGAGAAQAGDLLAMEWSRVRSRPNLSNCIGVDERNPCSDF"
     assembly_gap    17610..17709
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<17710..21771)
                     /locus_tag="P5537_02365"
     CDS             complement(<17710..21771)
                     /locus_tag="P5537_02365"
                     /inference="COORDINATES: protein motif:HMM:NF017658.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBG domain-containing protein"
                     /protein_id="HRV76918.1"
                     /translation="MKTIRPYRRAPAPRILAAALALAFSQAWPAWALPEGNTTAHGVV
                     EVGRPDASRMVIRQASDKAIVNWQGFSIGAGEQVRIEQPGAGSAILNRVTGASRSEIQ
                     GRLDANGKVFLINRNGVVFGETAAVNVGSLVASTLDIDNDDFVADRLRFRALEGPAAV
                     ENAGSISVADRGTVALMGGRVANNGTIRAQLGTVAMAAGEEMTLDLAGDGLSRLTVTR
                     ATLDALVANGGAVIADGGQVLLSARALAEVSSRVVNQTGVVRARGLSERGGRIVLDGG
                     DSGVTEVSGVLDASAPQAGGRGGEVQVLGHHVAVSGAAALDASGAAGGGAVLVGGDYQ
                     GRNPAVRNAKAAYVGPRASVKADATVAGTGGKVVAWSDEATRAHGSFSARGGPAGGDG
                     GVVETSGGFLDVSGARVSATAPAGKAGQWLLDPTDLRIVAGDANDNIEEEAGPVFFPV
                     GSPASIGAIVISNALNQGTSVVVRTGTADVEGEAGDITMERDTEQDPPAILYTGGGRV
                     SLTLEAHRDIRIEPGARIEAVGAGSLDVDLSADTAAAETGGVRILGAIIDTNGGALRI
                     FGQGDADNGYASGREDEVDLAGVRIEDSTIDTGAGDISIRGSGEGGREGVSLQGVIEE
                     SGAYSNTIEAPGGTVRIYGVGEIGGAGVQSSRTGILGGRGVLIDGTSAADDGVRLSES
                     RVEATLGAVNIIGLGEGNEVVSHGVNVLDSTISGFAGVDLRGENTHDDDGVKLERSVI
                     ESKAGSVGIFGKSLLAYGVYVPASSQQSPAGNSEIFGASGVEIRGESSFDAAVNLYRT
                     SIASGGGDVTIAGSSGTEIGVRLSYGPLDAEETSVRSGTGRLEITGDTTATSGLGLAL
                     GNVVLGGGDETQLGDIILRARNGGATDSIELHYFDDGITEPASILTAGSLVLVPGGVN
                     GGDPVRADAVPIGVGTSTGNGFEIEPRDLAAIEDVASVVFGSDTHTGQISTSASGLML
                     NADLTLQNEGDGSSGINFGGLEVSGHTLILASTGPLVQATGGSIVADALLVRATDAAN
                     IDLTKYANSVGTLAVDPPASFAFVNDGPVVIGPLSGPGYSTTSGTVQVLAAADSSAYG
                     DFFVQTINGSLTLGQSITTLDANSNITLVADGRFFAAPGAELTPGTGGRWQVWASTWG
                     TAADLGDLADDASRFYGCSFSDGCVTGVTLPATGNLMVFEGQPTLSIFARDASLTYGD
                     AIPELGYDPAVDGLVNGDLAADVLSGALGTTAVQGSPVGDYTIDNSSGGLVSPAGYLL
                     DVSEGSLTIDPASLLVTVDPVSRLYGAANPAFSAAVSGFVLGDTLANATTGTLALATP
                     ATERSAVGRYAVTASGLSAGNYLIESASSNAQAL"
     gene            complement(21809..23614)
                     /locus_tag="P5537_02370"
     CDS             complement(21809..23614)
                     /locus_tag="P5537_02370"
                     /inference="COORDINATES: protein motif:HMM:NF015803.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ShlB/FhaC/HecB family hemolysin
                     secretion/activation protein"
                     /protein_id="HRV76919.1"
                     /translation="MRTRSSGRRSTSSVTGVCVAAPEPVPHRRPLHGAFRIMKTARSS
                     GSNVYGLRACLVVGAVLAATPPSGAQMPPGAGDVLREASPPERVLPGTEQAPLLPERA
                     APAPAAAGGPSFVLRSVRFSGNTAFADAQLQAEVAPWLGKEVTFADLQAIAAQVSARY
                     RDAGFLLAEAIVPVQAIDDGRVELSVIEGRMGAVRATVDPVAPVREAVIRGITAGLPG
                     GEPLRGADLERTMLLLSDLPGLRPEAALEPGLEPGSVDLVLDVAPRRRWDLMVDVDNH
                     GSRSTSEYRAGLLGRINGPLRLGDNLDVRLQFGTGGRLAYGRVGYELPVGGQGTRFGV
                     SVARVEYELGQDFAALDASGEADLVEVGLTHPFVRSRARNLFGRLGWQEKRLDDRLDA
                     VGFSEDKKLRSFHAGLNYEQRDDWLGGGYMSAELTLYRGRLRLDPDALALDQAGRRSA
                     GNFTRWTYGLSRLNALMDKTSLYFAISGQFASRNLDSAEKVALGGPRAVRAYAPSEAT
                     VDVGHVATLELRRALTPELSVQLFHDWGWGRTDRHASGGTDNSVSLRGAGIGAFWSLA
                     GDTVLRTSLAWRTSARGEVDRDRVPRLYVQLTHAF"
     gene            complement(23547..25673)
                     /locus_tag="P5537_02375"
     CDS             complement(23547..25673)
                     /locus_tag="P5537_02375"
                     /inference="COORDINATES: protein motif:HMM:NF024180.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAT domain-containing protein"
                     /protein_id="HRV76920.1"
                     /translation="MSTMRARVRHAAAVLALCLVWGTGPSVFAQAVAGGGAVVFDSAQ
                     ARLRDAETLKALTAEGQLLYRRDRVRLDGYRYCSQAVSQAERGELRESIRSAARTLHV
                     GLAEGNEDLVALAKRDFAIAYSYAGDLDSAERHAREALQHVAKNPAIVAGPAYKTLGD
                     VATRRGRHDEAIGLYGKAAEVASERFRALVDLSLVNAYLSAGRSGEARAVFERQAAAE
                     PALAPLRARIEGRLLLAEGRVDEAAAAFESAARGAAGADADYNRLWALDGLARTWLAR
                     GDRREAQRRALEAATLAEGVRARFRSEEFKTGLFGDMQQVFELAVALSMELGETERAW
                     ALSERSRGRALLDTLRGRVDGGGRIDAAVGAVGLAELQAALLPGELLVQYHALEDRLV
                     AWVVAPGMLRGEVLPIARRDLEAIVDEFRRSIFRRAGDTRTLARALHARIVEPLGLPS
                     GSERLVVVPHGALHYLPFQALVGTEGRYLIEERGIVIAPSASVALQLARRGAGAAGAL
                     VAFGNPANQAREGLPGAEREVERISDLFPERRVYFREQASKERFRESAGAGRILHVAA
                     HAEVDAVDPLHSRILLAGAADDPGFLEAREVYEVDLGGVSLVTLSACESGLGRIARGD
                     EILGFTRAFLTAGAGGLVASLWPVADDSTEFLMTRFYAAFVRGTAAVEAMREAQVATL
                     RQAGFAHPFFWAPFNLIGDWRLRGGT"
     gene            26003..26848
                     /gene="nadC"
                     /locus_tag="P5537_02380"
     CDS             26003..26848
                     /gene="nadC"
                     /locus_tag="P5537_02380"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004360552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0019363 - pyridine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HRV76921.1"
                     /translation="MLSEQLRVEIQRNIAASLAEDIGTGDLTARLIAPDTEARGRVIT
                     REDAVVCGTAWFDAAFAALSPAAVVHWHVKDGDSVTAGQTLCEIAARARVLLTAERTA
                     LNFLQLLSGTATVTRRFVDAVAGTRARIVDTRKTLPGLRLAQKYAVAIGGGTNHRVGL
                     YDGILVKENHIIAAGGIREVVEQARTIAPSNVFIEVEVETLEQMREALEAGVKMILLD
                     NMTLEQMREAVAINAGRAELEASGGVNLERVRAIAETGVDRISIGTLTKDVRALDLSL
                     RHVER"
     gene            26893..27441
                     /locus_tag="P5537_02385"
     CDS             26893..27441
                     /locus_tag="P5537_02385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2946 family protein"
                     /protein_id="HRV76922.1"
                     /translation="MPQALPDWPMVPACHGWLALDARGCWRLRGETITHPGLIAFLAA
                     HYTADARGNWLVNNGPQRVYVELAAAPLILRLHPGGRLVTHSGREARATGPVLVDAEG
                     CAFLATDLGPGMIDDRDLALFAAELQHVDGAPAGDEALLALIDGQPDPELRWRDLDVV
                     SCARAEIPERLGFQPRPQALEP"
     gene            27595..27679
                     /locus_tag="P5537_02390"
     tRNA            27595..27679
                     /locus_tag="P5537_02390"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:27629..27631,aa:Leu,seq:gag)
     gene            complement(27798..29246)
                     /gene="thrC"
                     /locus_tag="P5537_02395"
     CDS             complement(27798..29246)
                     /gene="thrC"
                     /locus_tag="P5537_02395"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HRV76923.1"
                     /translation="MKYLSTRGHAGQPANPEFCDILLGGLAPDGGLYLPETYPQVTRA
                     ELDAWRSLSYAELAFAILSRFITDIPAADLKAICDKTYTAEVYRHVRKGDRASDITPV
                     HWLEEGRLGLLELSNGPTLAFKDMAMQLLGNLFEYVLAKRGETINILGATSGDTGSAA
                     EYAMRGKHGVRVFMLSPHGKMSAFQRAQMYSLQDDNIFNIAVTGMFDDAQDIVKAVSN
                     DHAFKAAHKIGAVNSINWARVAAQIVYYFKGYFAATKSNDEQVAFCVPSGNFGNICAG
                     HIARQMGLPVAKLILATNENDVLDEFFHSGVYRPRKAAETHVTSSPSMDISKASNFER
                     FVFDLVGRDPKKVAALWAEVDAGRAFDLSGTDEFARIGAFGFVSGASSHADRLATIRR
                     VYEQYGVIIDTHTADGVKVAWAHAAAVPAGVPVLVLETALPVKFAETIVEALGREPER
                     PADLEGIEKLPQRVEVMAPDTDAIKRFIAART"
     gene            29503..30369
                     /locus_tag="P5537_02400"
     CDS             29503..30369
                     /locus_tag="P5537_02400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance TerB family protein"
                     /protein_id="HRV76924.1"
                     /translation="MNLGNILGQILQQGMGQQGRSRLDHAMGPGGMADVLGGLLGGSG
                     PAGGAGGGLGGGLGDLLGDLLGGVLGGGRGGSTAGGMGDLGEILGGALGGGRATSGGG
                     GLGDLLGGLLGGGAAGSTGARSGGNAGMAILATIAMAALKNWTDNRRAQAAMAPDTAG
                     FATPELEAMTAPATEELVVRAMISAAKADGEVGEDEIQRIVGRVGADGLSEEEKQFMI
                     AELRRPLDLAALVAEVPNEMVAAEVYAASLLAIQLDTPAEAAYLRQLAQALRLDGATL
                     SRLHEITGASAV"
     gene            complement(30425..30637)
                     /locus_tag="P5537_02405"
     CDS             complement(30425..30637)
                     /locus_tag="P5537_02405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dodecin family protein"
                     /protein_id="HRV76925.1"
                     /translation="MSDRVYKLVEVVGTSHEGTDAAIRNAIETASRTIRHIDWFEVVE
                     TRGHVVDGKVAHFQVTLKIGFRLESE"
     gene            complement(30679..30825)
                     /locus_tag="P5537_02410"
     CDS             complement(30679..30825)
                     /locus_tag="P5537_02410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76926.1"
                     /translation="MVFKLIVFAAILIAIAVLGVRGYTAAVRRFEAANRLRGDGPRAE
                     PGAD"
     gene            complement(30968..31630)
                     /locus_tag="P5537_02415"
     CDS             complement(30968..31630)
                     /locus_tag="P5537_02415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015438151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HRV76927.1"
                     /translation="MQNKVDEVFVGKVRLLSIEGERSGIVKSPAAGPVMLTPTGLEGD
                     EQADLRHHGGVDKALHHYPVEHYAVLAAEWPQCAAAVGAGFLGENISTHGLDEHALCI
                     GDVLRIGEARVQVSQTRSPCWKIDLRLKVDGASRFVEAAGITGWYYRVLEPGLIAAGD
                     TIELLERPNPWLTLADYWDAVTAHRPDAVLLDRIAGAPGLAADKATRWRERAAWLRAH
                     AS"
     gene            complement(31746..33053)
                     /locus_tag="P5537_02420"
     CDS             complement(31746..33053)
                     /locus_tag="P5537_02420"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HRV76928.1"
                     /translation="MKPINVGLLGIGTVGGGTYTVLKRNAEEITRRAGRPIRIVTVAD
                     KNLALARQVTGGEVKLTDDAFSVVTDPGIDIVVELIGGYGVAKELVLKAIENGKHVVT
                     ANKALLAVHGNEIFAAAQKKGVMVAFEAAVAGGIPIIKALREGLTANRIEWLAGIING
                     TTNFILSEMRDKGLPFAEVLKEAQALGYAEADPTFDVEGVDAAHKATIMSAIAFGIPM
                     QFDKAYIEGISKLDSVDIGYAEQLGYRIKLLGIARRRENGVELRVHPTLIPEKRLIAN
                     VEGAMNAVLVQGDAVGATLYYGKGAGAEPTASAVIADLVDVTRLHTSDPEHRVPHLAF
                     QPDQVHDVPVLPIEEVVTSYYLRMRVEDKPGVLADITRILADSSISIEALIQKEAAEG
                     EAHTDIIMLTHQTAEKNANAAIARIEALPVVQGKVVKLRMETL"
     gene            complement(33120..34427)
                     /locus_tag="P5537_02425"
     CDS             complement(33120..34427)
                     /locus_tag="P5537_02425"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004380664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HRV76929.1"
                     /translation="MKAVKTLELATASPEPVIKAEAGAAAAPRPIRKSAKLAEVCYDI
                     RGPVLVRAKQMEDEGHKIIKLNIGNLAAFGFDSPEEIQMDMIRNLPNAAGYSDSKGIF
                     SARKAVMHYTQQKGIKGVGIEDIYIGNGVSELIVMAMNALLDAGDEVLVPAPDYPLWT
                     AAVSLSGGKPVHYLCDESKGWLPDIDDMRAKINANTRAIVVINPNNPTGAVYPDETLK
                     QIIALAREHDLILYADEVYDKVLYEGVKHTSMAALSEDVLTIIFNGLSKNYRSCGYRA
                     GWMVVCGDKRRANDYIEGLNMLASMRLCANVPGQYAIQTALGGYQSIDDLVAEGGRMR
                     RQRDLAWELINQIPGVSCVKPQATLYMFPRLDPKVYPIEDDQAFIAELLEEERVLLVQ
                     GSGFNWPHPDHFRLVFLPHEDDLRDAIGRIARFLETYRKRHGT"
     gene            34582..34965
                     /locus_tag="P5537_02430"
     CDS             34582..34965
                     /locus_tag="P5537_02430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004380661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mth938-like domain-containing protein"
                     /protein_id="HRV76930.1"
                     /translation="MKLYQDNHANTNVITGYGDDHVMISKTRHEGNVLVSASQVVAGW
                     APQAGGDLAGLTAADLARAAELGAEILIVGTGRRQRFPQPPLLRGLVEARVGFEFMDF
                     AAACRTYNILVAEGRAVVLGLLHDR"
     gene            35111..35566
                     /locus_tag="P5537_02435"
     CDS             35111..35566
                     /locus_tag="P5537_02435"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HRV76931.1"
                     /translation="MSAPLAPDFTLHATGGQTVTLSALRGRKLVIYFYPKDNTPGCTN
                     ETRDFGALQGEFAAAGCTILGISRDSLKSHENFKAKLELPFELASDPEETACEAFGVM
                     KLKNMYGKQVRGIERSTFLIDAEGTIAREWRGVKVPGHAEEVLAAARAL"
     gene            35679..37157
                     /locus_tag="P5537_02440"
     CDS             35679..37157
                     /locus_tag="P5537_02440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HRV76932.1"
                     /translation="MPVTRQSAAPASSPADAGAPAARRVRRSRKAAAASKLFVLDTNV
                     LMHDPTSLYRFEEHDLYVPIMTLEELDNNKKGTSEVARNARQASRMLDEIVSASENGI
                     AAGIALESPSRGLATGRLHLQTEAIDIRLPPALPTARGDNQILAVVMFLVEKHPGRDV
                     ILVSKDINMRIKARALGLAAQDYFNDKVLEDSDLLYTGTRELPADFWETHARGMQSWK
                     EEGRSYYRVSGPLAAEMLVNEFVYQDGDSPLQAWVKEQEGRGALIETLTDYSHNKNNV
                     WGITARNREQNFALNLLMNPEIDFVTLLGQAGTGKTLLTLAAGLTQVLESKRYTEIIM
                     TRVTVPVGEDIGFLPGTEEEKMAPWMGALEDNLDVLNGTAGEGGDWGRAATRDLIRSR
                     IKIKSLNFMRGRTFLNKFLIIDEAQNLTPKQMKTLITRAGPGTKVVCMGNIAQIDTPY
                     LTEGSSGLTFVVDRFKGWPHSGHITLQRGERSRLADHAAEVL"
     gene            37241..39139
                     /locus_tag="P5537_02445"
     CDS             37241..39139
                     /locus_tag="P5537_02445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008773 - [protein-PII]
                     uridylyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF294 nucleotidyltransferase-like
                     domain-containing protein"
                     /protein_id="HRV76933.1"
                     /translation="MSNDAATLLVGASTDFLRNFSPFNRMEAEALGFLAERAVLAFHA
                     RGSEILTPESGVPTHFHIVQRGKIQARQAGQATVTEYTSLTLGPGECFPIGAISARRP
                     STNAYVAVEDSFCFQISADDFLHLMQISPVFHLFCTQYIASLLSQSRQQLQSSFAQRA
                     AEQQTMTTALGKLIKQDPVFVTPDTPTRSALERMSELHLGCMVVVDAERHPVGILTQS
                     DLLPRVILAGFDLARPIGELMTANPHQLPASASAYDAVLEMATHGVRHLLVVDSESVL
                     LGVVSERDLFSLQRISLRQIRAGIDNAADIAALQRASKDIRQLALNLIAQGIGAEQLT
                     QFISALNDALTRRIITLAREHHDLVGIDFAWFAFGSEGRHEQTLSTDQDNGIIFRCAD
                     AKQVKETRTRLVEFARTVNEDLAACGFPLCKGNIMASNPELCLTLDEWKSRFGDWIRE
                     PDPQALLNASIFFDFRVLYGNERFGDQLRSALNKGAKGNSAFLRMMAANALKVMPPLG
                     RIRDFVVEEDGTIDLKKSGARLFVDVARILALRTGVESSSTVQRLRQGSNKIGMSPEE
                     VSAIIDGFNFIQLLRLRSQHLETEHDSADDNRIDPESLNELDRRILKEAFRQARKLQL
                     RLKLDYQL"
     gene            39136..39777
                     /locus_tag="P5537_02450"
     CDS             39136..39777
                     /locus_tag="P5537_02450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HRV76934.1"
                     /translation="MSWLSRLKIARGNQPPLSAEAERALEAWQALAEAGHEQPHFESR
                     YIVLNTEATGLDLERDRLLAVGAIAIDGGLLHPRDAYHAQLEPSPGDALAGLLAFVGR
                     SPLVVFNATFNRTILERAFARQLGFTPEFLWIDLYFLLPSLFPERLERPGRLADWMAA
                     FEIETFQRHHALGDAWAIAQLFLAAQSRALSLAVTNPRALAEHAQAYRQKLKV"
     gene            39868..40419
                     /locus_tag="P5537_02455"
     CDS             39868..40419
                     /locus_tag="P5537_02455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HRV76935.1"
                     /translation="MFFRPSLLILLAALALAHPAHAAEPVVATVEHGAKVPSTFDEYT
                     TAAEQLVDEALSYLGIRYRFGGTSPATGFDCSGLVLNVFRNAVGLDLPRTASEMASVG
                     DKIGKKDLKPGDLVFFNTMRRTFSHVGIYLGDGKFVHAPSSGGKVRVENISTAYWAKR
                     FNGARRLLDEEPLGLSAQVMGAR"
     gene            complement(40494..40835)
                     /locus_tag="P5537_02460"
     CDS             complement(40494..40835)
                     /locus_tag="P5537_02460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HRV76936.1"
                     /translation="MNALLVGADRLGNIPDVLHNFGIRIAAHVSGRDTTHQRRSAPLP
                     SGIGVVILFTDFLGHNVMQRFREAAGKQGVQVVCCRRSTCALQQALDRQMGARCEDCP
                     QRCEKARSRRR"
     gene            40953..41966
                     /locus_tag="P5537_02465"
     CDS             40953..41966
                     /locus_tag="P5537_02465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) ABC transporter substrate-binding
                     protein"
                     /protein_id="HRV76937.1"
                     /translation="MSKKVLLASLIAAFGLSGAATAAELNVYSARHYQTDEELYGNFT
                     KQTGIKINRIEAKEDELLERIRNEGANSPADIFVTVDASRLAKADEMGIFEPVKSAEL
                     EARIPSHLRAPNWFSYSTRARVIVYNPDMVKAEQVQTYEQLADPALKGQVCTRSGSHP
                     YNLSLGAAMIKHNGTEATENWAKGIVANFARAPKGGDTDQIRAVAAGECGVAIANSYY
                     LARLMNSDKREDQAVVAKIKAVWPNQASWGTHINVSGAGMLKHAPNKEAAVKFLEYLA
                     SDQAQEYFANGNNEWPAVPSVKLDNPALKKLGEFKADTLPIGELADTVAEAQRIFDRA
                     GYR"
     gene            complement(42029..44155)
                     /locus_tag="P5537_02470"
     CDS             complement(42029..44155)
                     /locus_tag="P5537_02470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MASE3 domain-containing protein"
                     /protein_id="HRV76938.1"
                     /translation="MLSVSASVLRRFRHPLLATVLLGVFFVFSIFLPPVNVFADALDY
                     LPLHAGLEIFAIVVAGMVFALGWNLRRSARGGRLVWLGAACLAAGLLDFAHLMSYPGM
                     PPFFTPNQAEKAIGFWLMARLIGALGLLAHAVLPEREGGGPAAAWAVLGAIVVTLGWS
                     WLVLAHPQVFPATFVEGRGVTPLKSALECGLALLYLGAAVLLARRALADGESVGGWLA
                     AAAVTMALAELHFARYAAVADLYNALGHAYKAAAFTMIYRAVFVSGVRAPQRALAAER
                     ALLRGLIDSVPDLIAFRDRDGRYLGCNKAFAEAYGIREDALIGRSDGEVFAGRLPLAE
                     AGQEAVSGAENHEEWLEAADGTLRLLDTLRTPYFDADGRQLGEIRVSRDFTERRRVRE
                     QIAERERRLMLALEGAELGLWDWDVPSGRANFSPVWCRMLGYTPDELAGNVSTWESLV
                     HPDDWYDIRDSLEPHLRGVRDAYRAEYRLKHKSGHWIWVLAAGRVLDRGEGGEALRMV
                     GIHQDISQRKAMEESLLQLATSDPLTGLWNRRHFMEVVRGELGRVRRNQAPAALLLMD
                     LDFFKRINDTHGHAAGDEVLRHFTATVSAQLREADVFARLGGEEFAILLPCIDALGAV
                     RVADRLRRVVADSPASIESGPLHYSVSIGATMLDARDEGYEGAYARADEALYAAKHAG
                     RNRVVLAPVIAGEAGEDVAGGNARIE"
     gene            complement(44356..45996)
                     /locus_tag="P5537_02475"
     CDS             complement(44356..45996)
                     /locus_tag="P5537_02475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HRV76939.1"
                     /translation="MRNRFSSLSVAAVVVAALIAAPVLSVFSNVLAGDTGATWSHLAD
                     TVLGEFVFNTVVLCIGVGLGVSSIGVTSAWLTTMLDFPGRRFLEWALVLPLAMPAYVM
                     AYVYTDFLQFVGPVQGWLRETFEWRRGDYWFPDVRTVGGAVAMFMFVLYPYVYMIART
                     AFLERAGGMLEAGRTLGLGPWGSFFRVSLPLARPAVVAGTALALMETLADFGTVSYFG
                     VQTFTTGIYRAWFSLGDRIAAAQLSAALLAFVILVLTLERMSRGRARFNNTSRQVAMP
                     VRLRLPLPLGLLAAFACFMPLLLGFLLPAGLLLRMAFLEGDAQFGARFVELAHNSFVL
                     AAITAVVAVLLAVLLAYAARLARSRLPQALNRIVGLGYAVPGSVIAVGVLIPLTRLDR
                     WLAEGWEAMWGFNPGLLLTGGIAALVYAYLARFLAVALQTVESSLGKITPNMDDASRS
                     LGFGKWATLRRVHMPMLRGSLLTAGLLVFVDVMKELPATLVIRPFNFDTLATQAHTLA
                     ADERLAEASTAALIIVAVGLLPMFWISRQILRVRRREG"
     gene            46150..>47209
                     /locus_tag="P5537_02480"
     CDS             46150..>47209
                     /locus_tag="P5537_02480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV76940.1"
                     /translation="MSHLDLSRIDLAFGSHLVVRQLSLQLEKGRIGCLLGPSGCGKTT
                     VLRCIAGFERLAGGEIRLDGEVVSTPRHMLPPERRRIGMVFQDYALFPHLSVADNIGF
                     GLRRDSAAVRAARVDELLALVGLAGQGHKYPHEMSGGQQQRVALARALAPKPSLLLLD
                     EPFSNLDVELRERLSYEVREIIKATDTTAILVTHDQHEAFAVADEIGIMHEGRIQQWD
                     TPYNLYHRPANRFVADFIGQGAFLRGKVLDDHRVQIELGVLDSAQPLVCCADCAGCVH
                     GSPVDVLLRPDDLVHDDTSPLRAEVVHKAFRGADILYTLRLAGGARVLSLVPSHHNHA
                     IGERIGIRLDVDHVVTFSD"
     assembly_gap    47210..47309
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <47310..47714
                     /locus_tag="P5537_02485"
     CDS             <47310..47714
                     /locus_tag="P5537_02485"
                     /EC_number="2.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008914 - leucyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0030163 - protein catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl/phenylalanyl-tRNA--protein transferase"
                     /protein_id="HRV76941.1"
                     /translation="APRAGGPGTWITPAMRAAYLHMHELGWAHSVECWRDGRLVGGLY
                     GMAIGRVFFGESMFARETDASKVALAHLARLLAERGYGMIDCQMTTAHLLSLGAREVP
                     RARFAAALRQWAHDGPSPQRWAEDAMRDFDWA"
     gene            47745..48473
                     /locus_tag="P5537_02490"
     CDS             47745..48473
                     /locus_tag="P5537_02490"
                     /EC_number="2.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004057 - arginyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0016598 - protein arginylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginyltransferase"
                     /protein_id="HRV76942.1"
                     /translation="MKSDYPYALIQFYATAPYACSYLAGRSARSQVATPGHLIDPQVY
                     SELVRRGFRRSGVFTYRPYCDHCQACVPVRIPVERFEPDRSQRRAWARHADLVPIERP
                     LDFVEEHYQLYQRYQTARHAGGGMDLDNREQYAHFLLQSHVDTRLVEFRSHGSLRMVC
                     VIDRLTDGLSSVYTFYDPDQPRSALGTWGVLWQVEACRVLGLPHVYLGYWIGESPKMA
                     YKARFRPLEALIDGDWQPFPGEFA"
     gene            48516..49523
                     /locus_tag="P5537_02495"
     CDS             48516..49523
                     /locus_tag="P5537_02495"
                     /EC_number="1.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006222 - UMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quinone-dependent dihydroorotate dehydrogenase"
                     /protein_id="HRV76943.1"
                     /translation="MLYELARPLLFALDPETAHNLTLHGLHYAGKLLPAAAPEPAGAV
                     EVMGLRFPNRIGLAAGLDKNGEAIDGLARLGFGFLEIGTITPRPQPGNPRPRMFRLPE
                     VHGIINRMGFNNHGVEVLLAHVRAAKYRGILGINIGKNFDTPIERAADDYLACLDAVY
                     ALASYVTVNISSPNTKNLRQLQGESELDDLLGRLKAAQTRLAEQHGRYVPLTLKIAPD
                     LDDAQVSNIADALRRHRIDGVIATNTTIARDKVQGLAHGNEQGGLSGAPVFEASTAVV
                     RKLAAALAGELPIIAAGGVLEGAQARAKLEAGAALVQLYSGLIYRGPALVRECVRATA
                     G"
     gene            49630..50718
                     /locus_tag="P5537_02500"
     CDS             49630..50718
                     /locus_tag="P5537_02500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HRV76944.1"
                     /translation="MTHRRKFMLSAAALAVAATLPFAAQAADAAKIGFVYVSPIGDAG
                     WTYQHEEGRKELEKALGGRIETRYVENVAEGADAERVIREFAASGSRIVFATSFGYMN
                     YVERVARQFPDVTFLHATGYKSAKNFAPYNARFYEGRYLNGVIAGKMTKSNVLGYVGA
                     FPIPEVLQGINAFTLGARSVNPNVEVRVIWANSWYDPGKEREAAMTLISQGADMLTHH
                     TDSTATVQAAEEKGVYAFGYHSDMSKYAPKSQLTATTHHWGEFYRRTVNAVLDGTWKP
                     EGVWGGMKDGMIRLAPLNPAIPADVQAMVKELQGRITAGSFHPFTGPVLDQAGKDRLA
                     AGAVMDDATLGKMDYFVQGVSSRLPTAR"
     gene            complement(50790..51533)
                     /locus_tag="P5537_02505"
     CDS             complement(50790..51533)
                     /locus_tag="P5537_02505"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HRV76945.1"
                     /translation="MLAAIAGGALAGGEGSGPIAVDVGHTLQAPGATSARGRSEFEFN
                     RDLSVHVVDALHARGWAVSILNADGRIASLRARPQAAGEAGAAFLLSLHHDSVNAFEL
                     RPWTWEGRARDYNDEFAGHSLFVSRDNPDTAMSILCARAIGARLQRMGFEPTHKNGRR
                     RSYADREHAVHYYDGLAVLRHARMPAVLFEAGVLKNRDEELLLRDPVRQARMADAIAT
                     GLSACLRNGLPADDEAGADRPDRAEPPGP"
     gene            51802..52227
                     /locus_tag="P5537_02510"
     CDS             51802..52227
                     /locus_tag="P5537_02510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c"
                     /protein_id="HRV76946.1"
                     /translation="MSGIFTKSMARNIFYGGTTFFFLLFLALTFDTERELPNRDNRAA
                     ITPEVAAGKHIWETRNCLGCHTLLGEGAYFAPELGNVYKRRGGDFIKGWMQAMPTGAP
                     GRRQMPQFNLTDEELDQLVAFLKYTSEINTANWPPNIEG"
     gene            52259..53641
                     /locus_tag="P5537_02515"
     CDS             52259..53641
                     /locus_tag="P5537_02515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004129 - cytochrome-c oxidase activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_process: GO:0009060 - aerobic respiration [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cbb3-type cytochrome c oxidase subunit I"
                     /protein_id="HRV76947.1"
                     /translation="MQYKSQAVAMPYFIAAIGLFVGQIIFGLILGLQYVVGDFLFPEI
                     PFNVARMVHTNLLIVWLLFGFMGAAYYLIPEETETELFSPKLALAMFWIFLVAGALTI
                     VGYLLVPYSTLASMTGNDILATMGREFLEQPLLTKVGIVIVALAFLFNITMTVLKGRK
                     TVISIVLLLGLWGLAIFFLFSFYNPVNLVRDKFYWWWVVHLWVEGVWELIMAAMLAFV
                     LIKVTGVDREVIEKWLYVIITLALVTGIIGTGHHYFWIGTPEYWQWWGSIFSALEPIP
                     FFAMTVFAFNMVNRRRREHPNKAAVLWALGTGVMAFLGAGVWGFLHTLAPVNYFTHGS
                     QITAAHGHMAFYGAYVMVVITMISYAMPILRGRAANPTKAQVLEMWAFWLMTIAMVFI
                     TLFLTAAGILQVWLQRVSDTPMSFMATQDQLMLFYWMREWVGVMFFIGLLAYLASFFV
                     KGDAKGVVHG"
     gene            53907..54953
                     /locus_tag="P5537_02520"
     CDS             53907..54953
                     /locus_tag="P5537_02520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glyceraldehyde 3-phosphate dehydrogenase
                     NAD-binding domain-containing protein"
                     /protein_id="HRV76948.1"
                     /translation="MHTSGAEHPFRIAINGYGRIGRCYLRALHEAGLAGRYRIVAINE
                     PADLASITYLTRFDSTHGRFPGVVDRSERELIVDGHAIHVSHASTPEEVDWAALGLDL
                     VVECSGQYGGRRDLQRFIAAGCPRLLLSHPGNGAEDVDATVVFGINEDALRGPERLVS
                     NASCTTNAVVPVLDCLHREIGIEQALLTTLHSAMNDQPLIDGYHHADLRRTRSAMQSI
                     IPVSTGLARGVERLLPALAGRVQAKAIRVPTHNVSAIDMVLSFGREVSAEAVNRLLRE
                     TAAGPQRGLLACSDEAHASIDFNHDPHSAIIDCSQTRAVGPRMLNLVVWFDNEWGFAN
                     RMVDVTCRWLAATG"
     gene            55020..55634
                     /locus_tag="P5537_02525"
     CDS             55020..55634
                     /locus_tag="P5537_02525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c oxidase subunit 3"
                     /protein_id="HRV76949.1"
                     /translation="MDTVTTPPSSMPAGGPAQTHAPRLAGDLAIWFFILAELLAFGVF
                     FAAYAFARAKNIELFAAEQAALNRNAGALNTVLLLTASYFVVRAVQAAEAQASRQCAN
                     WLGGAILTGFGFIVVKLSEYAAAFEHNISLSSSTFHMFYLSLTFFHFMHVILGLVILI
                     AMWNGARQGRYRPGEMNGLETGAAYWHMVDLVWLILFPLVYVIH"
     gene            55645..55926
                     /locus_tag="P5537_02530"
     CDS             55645..55926
                     /locus_tag="P5537_02530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome C oxidase subunit IV family protein"
                     /protein_id="HRV76950.1"
                     /translation="MSARMHGTPRGSTILFATLILATFATWGMGSLGVTGTWGVAILA
                     AISFWKGAVVILDFMALRHAPLLWRAITMGWIIVVWALIAIAYIKGLAQ"
     gene            55923..56723
                     /locus_tag="P5537_02535"
     CDS             55923..56723
                     /locus_tag="P5537_02535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CbbQ/NirQ/NorQ/GpvN family protein"
                     /protein_id="HRV76951.1"
                     /translation="MKPDTPNLDIPFYQPAGDEVDIFQHAWKNRLPLLIKGPTGCGKT
                     RFVSHMAARLGLPLYTVACHDDLTASDLVGRHLIGDGKTMWCDGPLTRAVREGGICYL
                     DEVVEARKDTTVVLHPLADDRRVLPIDRTGELLEAPPSFMLVVSYNPGYQNLLKGMKP
                     STRQRFVSLRFDFPRPEQEEAVLIGETACAPDLARRLVAIANALRALKDRDLEEAAST
                     RLLVYTALLVKDGMDPVAASRVGIVESLTDDADVAEGLMEVVAATFGR"
     gene            56740..57147
                     /locus_tag="P5537_02540"
     CDS             56740..57147
                     /locus_tag="P5537_02540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76952.1"
                     /translation="MEIKRADPLRHVMPGPRLAVVAEALFLINLMLLPGLAFAALMVL
                     WYLHRGHPDPLVRNHLRQTGWTCIWGGLLLVVISVAIFLLGGFDNPWTWVIGVLYFTF
                     VHSTLILLGVMGLSRAINGRSWRFPVFGPRESS"
     gene            57165..>57539
                     /locus_tag="P5537_02545"
     CDS             57165..>57539
                     /locus_tag="P5537_02545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HRV76953.1"
                     /translation="MNTEAPARKPQRVIPIATAPAGDAAAAAAMQRRRRAFQAGFFAL
                     FVLAPVFDLFRYDLDADHAWLLGMEWRLGLDPFLAGQASALEAAGSIILNLFVPLLAL
                     AALVIGAAWKWGRLYCGWLCPHF"
BASE COUNT         9109 a        20694 c        18584 g         8952 t
ORIGIN      
        1 ggcgacctcc tcccgcttct gccaccactc cttgcctttc ttgccgacca gcacctgcgc
       61 gatctcgaac atgttcttct tgagcggacg ggcgacacgc caagtcatcg tcaggcgttc
      121 ctggtcgggc tcgaagacga tggtgtcgag catcgcctta tagtcctcgc gctcgccctt
      181 cttcggaaac acatggaccg gggcttcgaa gtccggaagt gtgaagctgc gcctgccgtc
      241 ggcggtgaga ttgatcagcg tcacctccgg cccgccgatc ggtatcgcca attgctggtc
      301 cggcggggcg gacaggtaat agcgctcgtc gaaatccgcc ggcaggaagg ggaagacctt
      361 gtcgagccag tcctggtcgt aggtgccggc gtagcggtag cgcggttccc agttgcggcc
      421 gatggggccg aaggccatcg gtgcgaagtc gccgtcgggc cggtcgaccg ggcggttcag
      481 ctcttccgtg ttcggcaagg gcttgccatc cacccattcg ctcttgagtt gaaggcggta
      541 gccgcgtccg accggattgc gcatgcaggc gccgtgcttg gcgaaatcct catgttcgtt
      601 gtcgacgccg ccgaaggcta cgtcatacgc gatcggcttg atgacgaaag gctccggcgg
      661 gctggcgctg atccgaccca ggccgacctc ccagtgccgg tcgccgacca ccgcgaagcg
      721 cttggtcatg ttgccgacgc gcagccctac agggacccgc gtcagcgggc gtccgtccgg
      781 cgcgtaggcg ctacccagca gcaggacgtc gcagcacggc ttgcgcggcg cgaagtcggc
      841 ctcgtacatc ggcgcggaaa accccggctc cccggtgaag gtgtccgcca tcaccagagg
      901 cagctgttcc tcgtgcagtc ggacctcttc gccgttcctg ggcaggtgga aggtgccctt
      961 gatcaccacg accagcagct ctctcccgct gggctcgatg cccatcgtgt agccggcgag
     1021 catgcgggtg gcgttgatga gttccatggc gcggatcgct cgtcggcacg attcagttga
     1081 gctggatgct gccgcccttg acgcggttca cacccgagga gcggctcgat acataggtcc
     1141 cttgaatgag caccttgccg gacttggtga gcgtcacgct cgccttgccg cagcgcagga
     1201 cgagttgctc cctggcgctg acggtcatgc gctcgccatc gacgtcgagc tcgacctgcc
     1261 cgggacgctc ctccagaggc cagccttcgc cctggcgaag cacgcccatg acgatgggcc
     1321 gcagcggatc gccgccttcg aacatcagca ccatgcgctt gccgatgtgc gcgccatgca
     1381 gatcgacggt gctgcgggcg ccgatcgcgg ccgtgccggg ttgcccgggg tagagcacga
     1441 ggggcgtgcg gccttcgtcg gcaatggcga caagctcgcc gaccaggacg ccatcgaccc
     1501 gctgtggcgc gctggtgact gccgacgcgc cttcgagcag cggctgcaac agttcggcgc
     1561 catcgcgaaa cgtcgccttc ggcaagctcg aaccctcgat cggatccctt ccactcatgg
     1621 tcttctccat cagttctgca ggatcttcga gcccttcatc accacgttgg cccccgcctt
     1681 cacgttgatc tttccggagc cctcgatggt gatgtccttg cccttgatcg tgatcgtgcc
     1741 gtccttcttc atgctgatgc tggcgctgcc ggtcttgatc gtgaccgagt cgcccgcgtc
     1801 gatgacgagg ttcttgccca ccttcagcga gtcatccttg ccgacgttcg tgccgcggcc
     1861 gccgcccacg tcgcgcgatt cgtcggcacc gacggaggtc gacaggttcg cccccacatt
     1921 caccgactgg aaggcgccga tcgccacttc ctgcgccgca ccgatggcga tggtctcgtt
     1981 cacgcccacg gtgtgcgtgc gctggagcgc gacggtcttg gtctcgttgg cccccacggt
     2041 gacgctgcgg tcgctgccga tcgtgatgct ctcgttcaca cccacatcct cgctgcggtt
     2101 ggccccgatc gagatcttct cgtcgatgtc gacccgctcg ctgcggttct ggtggatggt
     2161 gatcgtctcg tccttgtcca ccgtctcggt gcgctggccg tggatggtga tggtctcgtt
     2221 gttgtcgacc gtctcggtgc ggtcgtgctt gacgtgggtg gtctcgtcgt tgtcgatggt
     2281 cttcatgcgg tcgtgcccga cccagtgcgt ctcgtcgttc tcgacctcga tgtcctggtt
     2341 cttctcggcg tggatccaga gctgctcgct gcccttcttg tcctcgaagc gaatggcgtt
     2401 ggcgttggcg ccgctgccgc cgagcgagga gcgcgtcagc acgccggtct gggtcttgtt
     2461 ggcgggcagt tcccagggcg gcatctgctc ggcgttgtag acgcggccgg tgatgagcgg
     2521 tcggtcgggg tcgccctcca ggaactcgac caccacctcc tggccgatgc gcggcatcgc
     2581 caccatgccg aagttcttgc ccgcccacgg atgcgacacg cggatccagc acgaggcgtt
     2641 ctcgtcgtcc ttgccgtggc ggtcccactg gaagtgcacc ttcacccggc cgtactcgtc
     2701 ggtgtagatc tcgtcgccgg cggggccgac cacgatcgcc gtctgcaggc cttgcaccag
     2761 cggcttgcgc gtggtgcgct gggtgcggaa aggcaggtcg ctggcgatgc agtcgaagct
     2821 gctgcgaaag ctcgccccct ctccaccacc ggcctcatgc gcggcgagca cgaaatcgag
     2881 gcggctcgca gtgatcaaat acttgcggtt ctggtcctcg cgtggctgct cctcgagctc
     2941 gaacacgcag cccgtcgcga tcccacgcgc attgccggcc ccttgcatga tctgcacctg
     3001 cgactgcagt tcctccaggc ggatgcgtac gtaggcctcg ccctcgccct tgctgtcgta
     3061 ttcgcccggg tagtcgtaga tctcgtgctc cgcttcggcg tagtcgcgct tgtgtcgggt
     3121 ctgctgcagc agctcgacgc tcggcttctt gaagtcgaag tcgtcgatgg cgtacgcccc
     3181 cggctgcacc tcccaggaaa agccccattc ggtgatccgc tcccgctcga tgcgcagcgc
     3241 gcgctcgccg ctgacgaagg ggagctgcgc gtagcccggg taaggctcgt gcgcgctcgg
     3301 cgaatcgcac aacaccgcgg tgtgcttgcc gtccttgtgg gtgaagtagt agtagatccc
     3361 ctgctgctcc atcagccggc tgacgaagtt gaagtcggtc tcgcggtact gcacgcagta
     3421 ttcccacggc tcgtacgtgc ccgtgaggcg atcgagctcg taggcggcga tcgagtactt
     3481 gccgaagatc tccgcgatga tctcgggcac cttctgattc tggaagatgc ggcagtccgc
     3541 gcagcgggtg aggaaccaca gccagggccg ccccacgatg cgatagcgca ggtagcgccc
     3601 aagcactccc acgagcgaga aggccgtcac gtaggcatcg aagtggcgct cgccaccgtc
     3661 gggcagctcg accctgaccg tcacgttgtg cccgagcagc ttgttcgggt cgatgtcgtt
     3721 tcgctcgctc agcacatcga tctggtattc gaagagccga ccgagttcct cgcgcgtgga
     3781 gatcgcgtga aagagcagca ctccgtcacc gagcggcgtg gtgatctcca tgacccgcgg
     3841 catacggttc ccctctgggc tctcatgcat tctttctagg caatcgcccg ccaaaacgcc
     3901 agcacgcgat tgcccgcgcg cgggccacgc cggaccggcg gatcagggct tgcaagcccc
     3961 gaccagccag cccgcgactg gctccccgcc ctccgtgcgc aacacctgcg cgctcggcaa
     4021 ggcagcctcg aagcctgccg ccacgagcgc cgcgaccacg tggttgcgag tgtgggcgta
     4081 gcgcccgttg ggctggagga tgaagggcgg cccggcgtcc tcgtcgccaa ccgcctcgac
     4141 ggtgaagaag agccgtccgc cgcggcgcag cgcgccgtgc gccgcggcga gcaccgcacc
     4201 cagatcgccg aagtagcaca gcgtgtcggc cgacagcacc acgtcccagg ctgccggccg
     4261 ggcggcgagg aaggcgccga gttcggcctt gtggagctgg tcgtagacgc cgcggcgctc
     4321 ggcacgctgc agcatctgcg ccgacaggtc cacgccctcg agccgtcgcg cgtgggcgcg
     4381 cacgagcgga ccgcacaggc cggtaccgca gcccgcatcg aggacatcga gcgtcgccgc
     4441 cggcgccccg tacgcctcct ccagcgcctg cgccacctgc atcggcgcac ggtagtgcag
     4501 gcgctgcagc ttctcgtcga agctggaggc gaaggcgtcg aaggtgcgct cgacgtagtc
     4561 gtccgctgcg cgcgccggca cggcctcgcc ggtgcaggcg gcgaggtgat ggcgcgcgat
     4621 cgggttgtcc ggctcgtcgg cgagccagct gcggtacacg tctgcggcct tgtcgaactc
     4681 gcccagggtg tagtacgcca gcccgagcag cttgcgcgcc ccgacctggc cgggggatgc
     4741 ggtgatcgcc cggcaggcgt ggtcgaccgc cgcgcgcagc cgaccgcgcg cgagcatcaa
     4801 gccggcgagg ttgttgtgca cgtccgcgag cagctccgcc ggctcgcctg cctcgacacg
     4861 cgcttgcgcg agctgcagcg cgcgctggta agcctcctcg gcgaggctcc actcgctgcg
     4921 gctgcggtgg atcgtaccga ggttgttgtg cgcctcggca aagtcgggca tgagctccag
     4981 gcagcgacgg taggcggcga tcgcgtcgtc gacgctgccg gactcgagca gcacgttacc
     5041 gaggttgttc caggcgccgg gtgcatcggg caccagcgcg agcgcgcgcc ggatcagtgc
     5101 gctcgcctcg gcgctgtcac cgcgcgcgtg gcggagcatg ccgagcaggt gcaagacctc
     5161 ggcctcgtcc gggcacaggc cgaggatcgc gcgatagatc ttctcggccg ggtccagata
     5221 ccccgcgcgg tgcaggcgca gcgcgtgccc gagcgcctcg tcgacgctca tcggcgcctc
     5281 gcccgccgtc gcggcgggcg cggaaggtgc ggagctcatc ccgcctcccc gcccgcgggt
     5341 gcggcgtcga aggacaggcg gaagtcaccc tccgccacgc cgacctgtac ccggtcgacc
     5401 gccctgcctt cgaccatgcg ggtgaggaac tcctggctga tgcgcggcaa cagggtgttg
     5461 gtcagcagcg cgtcgatcat gcgcgcgccg ctctcgacct cggtgcagcg gccgatgatc
     5521 agcttcacca cctcctcgtc gaaactgaac tcgatcttgt ggttgtcgtg gatgcggcgg
     5581 ccgatgcgct tcaactgcag gcgggcgatc aggccgatga tcgcgtccgt cagcgggtag
     5641 tacgggatca ccaccagccg gccgagcagc gcgggcggga agaccttgag cagcggctcg
     5701 cgcagcgcgc gcgcgatgcc ctcggggtcg ggcagcagct cggggtcctt gcacaggccc
     5761 atgatgaggt cggtgccgac gttggtggtg atgaggatca gcgtgttctt gaagctgatc
     5821 accctgccct cgccgtcttc catccagccc ttgtcgaaga cctggaagaa gagctcgtgc
     5881 acatccgggt gcgccttctc catctcgtcg agcagcacca ccgagtaggg gcgccggcgc
     5941 accgcctcgg tcagcacgcc gccctcgccg tagcccacgt agccgggcgg cgcgcccttg
     6001 agcgtggaga ccgtgtgcgc ctcctggtac tcgctcatgt tgatggtgat cacgttctgc
     6061 tcgccgccgt agagcgcctc ggcgagcgcg agcgcggtct cggtcttgcc cacgcccgag
     6121 ctgccggcga gcatgaacac gccgatcggc ttgttcgggt tgtccaggcg cgcacgcgag
     6181 gtctggatgc ggcgggcgat catctcgagc gcatgacgct ggccgatgat gcgctgctcc
     6241 agggtgtcgg ccaggtgcag cacggcctcg atctcgttct tgaccatgcg cccgaccggg
     6301 atgccggtcc agtcggccac cacgctggcg accgactgct cgtccaccgt gggcatgatc
     6361 aggggcgtct cgccctgcag gccgcgcaga tgttcctgca gggtcttgag ctgctccagc
     6421 agggcggcgc ggtcctcggc gggtggctgc acggctgcgg caccggcctc gtctgccccg
     6481 ccggctgccg tcgcagcagg ggccgcgggc gccggctcca gcgctgccgc gggggcgtcc
     6541 gcgggcgccg aagcgtcggc gggcggggcc tgcgccgcca gttcgccggc gtcgcccgaa
     6601 ggcggcgtgc tcgcagcgag ctccggtgca gccggctcga cgtcggcggg cgggtgatcg
     6661 acgcgctcgc ccccggcccg cagcttgccg cgcagctcga ggatctggtc gaccagaccc
     6721 ttctcctcct tccagcgcgc ctcgagctcg ccaaggcggg cgagctcctg cgcccggcgc
     6781 gcctcggcat cgccacggcg cgtaccgatc tcgatgccga ccagctcctc gcgcccgatg
     6841 atctcgagct cggtatcgag cgcctcgatg cggcgccggc agtcctcgac ctcggccggc
     6901 gtcgcgtgct ggctcaccgc cacccgggcg caggcggtgt cgagcaggct caccgccttg
     6961 tcgggcagct ggcgtgcggg gatgtagcgg tgcgagagcc tcaccgccgc ctccatggcc
     7021 tcgtcgagca gctgcacgcg gtggtgcttc tccagcaccg tcgccacgcc gcgcagcatc
     7081 agggtggcct tggcctcgtc gggctcctgc acctggatca tctggaagcg ccgcgtcagc
     7141 gccgggtcct tctcgatgta cttcttgtac tccgcccagg tggtggcgcc gatcgtgcgc
     7201 aggttgccgc gggcgagcgc gggcttgagc aggttggcgg cgtcacccgt gccggccgtg
     7261 ccgccggcgc cgatcagggt gtggatttcg tcgatgaaaa ggatgatcgg cttcgggctg
     7321 gcctgcacct cgtcgatgac ctggcgcagg cgctgctcga actcgccctt catgctcgcc
     7381 ccggcctgca gcaggccgat gtccagcgtg aggagcttga cgccctgaag cagcggcggc
     7441 acgtcgccct gcacgatgcg ctgggcgaag ccctccacca ccgccgtctt gccgacgccg
     7501 gcctcgccgg tgatgatcgg gttgttctgg cgccggcgca tcaggatgtc gacgatctgg
     7561 cggatctcct cgtcgcggcc gcgcaccgga tcgacctcgc ccttgcgcgc cttctcggtg
     7621 aggtcgatgg cgaacttgtg cagggcctcc tgcttgccga gcgcggccgg cgccatcgcg
     7681 ccgctggcct cgccgggctc ggcggtggag ccgctcgctt cgccgaggag gtcctcgggc
     7741 gaaccgctga cgacctgcac cagcgcctcg gacaggtcct ccgcgcggat gcgctcgaac
     7801 tggcgcgaga tcgcgtacag cgcgttgcgc aggtaggtcg tcttgagcat tccgagcagc
     7861 aggtagccgg tgcgcaccgc gttgtcgccg aacatcagcg agccatagac ccagccgcgc
     7921 tcgatcgcgt tggtgatgtt ctccgacagg tcggtgatcg aggtcgcacc gcgcggcagg
     7981 cggtcgagcg cggtggtgat gtcgcgcgcg agcacggcca tgtcgacctg gtagtgcttg
     8041 atgatgcggt gccagtcgct gtcctgcgcc tgcacgatct gcatcaccca gtgctcgagc
     8101 tcgacatagg ggttgccgcg cagcttgcag aacacggtcg ccccctcgat cgccttgtag
     8161 gccacccggt tcagctttcc gaacaacgcc atccggctga tctcgctcat tccccttctc
     8221 cttgcaatgg cctgctcaat tcaccttgcg cgcccgtcgc gcgagcgcgt cctcggcatg
     8281 cagcgcgagc ggggcgggat cgtcctcgcc gcgcggcctg ccgagccagc tcgtccatcc
     8341 caggcgctgt ccacctccca ggcgcagcgc cggcacctcc gggcggcgca acaccagacg
     8401 cacgtcccag tcgagttcga aacacaggta ctgccgcacc agcgcgagca ggcgcggcaa
     8461 ggactggcct cccggcagga aggcctcgta gtccgcgagc cccatcggcc cgagccggat
     8521 gcggaactgg tgctgccgat cccaaaccct ggcgcccagc accaccccga accccaggcg
     8581 tgcgcccatg gagccgctgc ccagtcgcgt acgctccgcc tcgggcagcc tcatccagtg
     8641 gccgacgaag ctttccaccc gcgcagccac gccgaaatag tccgccagga tcgcctgcag
     8701 cccgtcgcca ttgcgcacct ggcgggcgaa caggccggaa tggaagagct tgacccgatc
     8761 ccccgccgcg tcgcgcccgc gcaggcgatc cggaccgatg cccagcagcg cgccgacgta
     8821 catcgcgaag cgatcctgcg ccgggcggtc gagcgacacg tccggctgcg cctgcgccca
     8881 gccgcggtag aacagcgcca gcaggcggtg gtgaaagaga tcgaggaagc tcgcgaaggt
     8941 cgcgtcgccg tgatgcagct gacgctcgcg ggcgtagtcg gtgagatgca gcggcaaggg
     9001 cccgttgggg ccgagcaggc cgaagatgcg ctgcaccagc tcgggcgggc gggcgtcctc
     9061 ggcgggccgg aaggccgcga tcggcgcggg cgcgaaggac atcgacgcct cctgcgccag
     9121 gcgcacgggc tcgtcggccg ggcgcagcgc ctgccccagc ctgggcttgt ccgcgaacag
     9181 gcattcgatg cggcgcaggg tctggtagaa gtcgtacgcg tacggcttct gctcgagcgc
     9241 gcgcaggaag gctagacgat cggccgattc ccgcatcgcg gcacccaacg catgatctcg
     9301 ccgcggccac tcgcgcgcag caccgtctcg acgaaggagt tgatcgacac gtagcgtccg
     9361 agaaaacgct ccatcaccgc gccgaagagg aaggcgctcc cgccctggaa ggccatctcg
     9421 tcgatctcga gctcgacctc cagcccacgt ccgaagctca ccgggccggg cagcgggaag
     9481 cgccgcacca cgggattgac ccgcagcgcg cgcaggcctt cgacctgccg cacgaccgcg
     9541 ccgtctcccg cgagcgcgta cagctcgagc atctcgcgca tggctgcggc cgcatcgccg
     9601 gcgtcgccat gggaaagcga caggtagttc agcgacaggt ggctgatgaa ctgccacgcc
     9661 acgctgccct cgcgcagcgc cgaaaccggc cgcgtcgggc ccttgatcac ccgcaccgcg
     9721 ctcaccggcg cggcggaatc cagggtgaag tcggtcttgc ccagcccgat cggcatctgc
     9781 agcggcagat cgcggttcgt gcacagcacc cgcaccgaaa gctgccgcag ctcgtcggaa
     9841 tagggagcct cctcggggtc gaccagggag atgaacacct cgctgccgac gtagctcgtg
     9901 cgggtgccgc ggcgcttctg ctcctcggtc agcaggcgcg gttcgcgctg ctggcaaaaa
     9961 tacgccgcat gttgcgccga ctcatgatgg aaggccgcat agagcggaag gaactcgcgt
    10021 tgcgcctgca cgccgccgct gccgaagccg gtcaccgact cgatcgcatg gacctcgaaa
    10081 tcgatcgggc gggtgcgatc gacgacgacg tggtagtcgt ggctgccatc cccgacgtgg
    10141 atgcggtcgg cgttgcgctc gagcaggttg atggccggcg cgcagaacag cctgaggttg
    10201 gcggcatcga ccacgccctc gagcgtgggg tcgccgcgcg agaacagcag cacgatctcc
    10261 agctcgctgc cacggcacgc gcgcgcgggt gcgccgagac cgtgcaggtc gatgaagcag
    10321 aagcgctggg gaaaggcggc gtactcgtgg aacagccgat agccctggaa tccgcgcagg
    10381 ttgaccggca gcagggcctc gtcatcctcg aagccgagcg cacgcacctc gctcgcgggc
    10441 acgaaccggc tcgacgacgc gccctcccct accggctgca cgagcatgcc tacgcaggcc
    10501 ccgagcgcga gctcgtagag cttgaaggcc acctcgtcga cgccgccgag atggatcggc
    10561 aggcgggcga gctcgagatc ggcgatcccc agccccgcac cgctgcgcaa gcggatgcgc
    10621 agcccgccct tgacccggcg cccgtcaggc agctgctgca ggggcaggtc gggggcgaag
    10681 gagaagtagc tggccgcgac cacctccagc ggcagcagac acacctcgtg cgcggtgcgg
    10741 aactcgcacg cggtcgtctc accgcgcgcg accgtgccgt gcatcgtgct gccgcgcggg
    10801 atacggaaac cgcgcgccag gttggcatcc tggatgtccg gctggaactg cgcgatcacc
    10861 atcgccggcg tgggcgccag gaactgcgga tagacgatct ccagcatgcg ctgcgtgaag
    10921 cgcgggaact cggcatcgag cttgagctgc acgcgcgcgg cgaggaaggc gaaaccctcg
    10981 agcagacgct cgacataggg atccgcgacc tcgatgccgt gcatgcccag ccgcgcagcc
    11041 accttgggga actgcgccgc gaactcggcc cccatctcgc gtacatggcg cagttcctgg
    11101 tcgtagtagc gcagcaggcg cggatccatg attcagcgcc cgagatcctg gatctcgatc
    11161 tggccggtct cgagatcgac gttggtgcgc agcagcagct cgatcggcgt cggctgtgcc
    11221 cacaggctgc cgcggatctc cacctcgatg cggttgtggc gatcgagcgc gatctgctcg
    11281 gcgagggcgc gcagcttgag gctgccaggg tcgatgcgcg gttcgaactc gaggatcgcc
    11341 tggcgcatcg cgcgctcgag ctggatcacg tcgagcgtcg aggccgtctc gcccgcaagc
    11401 gcgggaaggc cgaaattgac caccgagcgc agcgccagag gcgctccggg ccagtcgtcc
    11461 gcatcggccg cgcgtgttgc attgaacagc cagcccagat cccgcagcac gctctggcgc
    11521 atgtgctggc gggagatcag tcgctccgcg cgcggctcga gcgcgcgatc cggctcatcg
    11581 tcggtcaggc ggtcgagcaa ggctggctgc aatcgatcct tcgggacgct gtcagccatg
    11641 gtctggcgca atctccgcat cctcgccgag gcgcacctgc cggatgtcga gcagcggata
    11701 ctcaccgacg tcggtcgcca gcacgcgctg tccgaggccg cagaaaaccc cgctccggct
    11761 ctcgctccag accgacttgc gcgcgagcgc gatcagtccg tcgtcgaccg actccgaacc
    11821 cgggtagcgc accgggatca gcgcgacgga ctcgcccccg ttgatgaagc gaagatgggc
    11881 tggcaaccag acggagtcgc gcagatcggt cggctcctcg aggtcgatgc gcgccaggcg
    11941 gcagaacgga atccagtagt agcgcccgtt cacgatggcc tcgagcaccg gccccaggcg
    12001 catgtcgcaa tcggcgatcc acgcgaaggc cttgccatcg acgctgccgc tggtggtggg
    12061 tgcaagctcg aaggcctgct ggcgcagccg ctcgccggcc tcctcctcgc cccgccccgc
    12121 acgcagcagg gattcgatca acagcgcgat ccaggtctcg ggctcgccga acagcatcgg
    12181 cgagcggatc ccggcgaaga cgtcggcgcg cacgcgctcg caggcgatcg cgtcgcggta
    12241 ggtctcgcgc atcgcgatcg cggcggcatc catctcggcg cacacctcga gctggctcag
    12301 cgcccgctcc cagcgcccga gcacgcacag caactggaac aggaacacgc gcaggcgcac
    12361 gtcctcgggc ttggcacgga tggcgtcctg gagccgatcg agtgcaagcg gaagatcgcc
    12421 tgcccggacc gcattctcgg catcggtaat cattcgacct cccgggttag gccccgtcag
    12481 cgtggatgaa ggcaggcgcg ctcagatcgt ctcggcctcg aacaacatcg agcccattcc
    12541 cagcccgtcc ggcccctgcg gtacatattc gatactgatc ttctggaacg agaagctgag
    12601 ccgttcgacg agctcggggt gctcctcgcc caccgattcc acgtcgagcg aggtgatccg
    12661 gccctgctcc atcaccacga tgtagtaatc cagcggtgcc ttgccggcct tgcgcacggt
    12721 gagcgtggcc ttcttgatca ggtcgttgtt gcgcagcgcc gccatcaacg gagtcgacgc
    12781 gctgtccacc cgcttgctga tcaggaactc gcgcatcgac gccttcgcca ggcttccccc
    12841 gccgcccatc tcggtctggg cgtgcatgcc ccaggaccac gagacgacgt cgatctcgcc
    12901 cttgcgctcc gcatcttcgg attcgccctt gatcgttccc gaccgggcgc cctccacctt
    12961 gaggaacatg tcgctcttgg ccatgctcgg atccccgccc atcgaccaca aggataggaa
    13021 gcccgggggc cgctgcagcg cccccgggcc gccggccgcc gcatcaggcc ggctggttct
    13081 tcgcgatgct ccaggcgact tccttggccg agtcgccggt gccatcctcc ttctgcgggg
    13141 tgtactcgag cttgaactcg gcgaagttga gcgagatgct ctcggtcagc cggtcctcgc
    13201 caccactccc gccggtcgcc accgaggtga cgatcacttc cttcatggtc agcttgatgt
    13261 actcgagcgc ctccttgccg gccttgcgca ccgtgatctt cgcctccttg aagtgactgc
    13321 cgtcgcagca ggccttgatc agggcgtggg tggacgcgtc gacgtacttg acgaagttga
    13381 tgtcctgcac cgagaccttc cccgatccgc cgccgccccc ggtgtgggtc gtccccgact
    13441 gggacatgcc ccaactccag gacaggacgt cgatctcctt tgcgtgcttg ccgtcggccg
    13501 actcgccttg gatgtcgccg atcttgatga acatatctac agccatgatg actctcccat
    13561 atcgagggca cacgagcgaa cgagcgcggc ggaaccgggg cccgcgccgc gcccctggtc
    13621 cttacgccgc cttggccgat ggcagcttgg acaccaacct gagcgacacc gtcagcccct
    13681 cgagctgata gtgcggccgc aggaagaact tcgacgtgta gtagcccggg ttgccttcca
    13741 cctcctcgac caccacctct gccgccgcca gcggcttacg ggccttggtc tgctcggagg
    13801 agtgggccgg gtccccatcc acgtaattca tgatccactt ctgcagccag cgctgcatgt
    13861 cctcgcgctc cttgaacgaa ccgaccttgt cgcgcacgat gcacttcagg taatgcgcga
    13921 agcggcagca ggcgaacaga tacggcaggc gcgcggccag gttggcgttc gcggtggcgt
    13981 cgggatcgtc gtattcgaag ggcttctgca gcgactgcgc gccgatgaag gcggcgaagt
    14041 cggagttctt gcgatgcacg atcggcatga agccgttctt cgccagttcg gcctcgcggc
    14101 ggtcggagat cgcgatctcg gtgggacact tcatgtccac cccgccgtcg tcggtcggga
    14161 aggtatgcac cggcaggcct tcgacggcgc cgcccgattc gatgccgcgg atccgcgaac
    14221 accagccata gagcttgaac gagcggttga tgttcaccgc catcgcatac gccgcgttgg
    14281 cccaggtgta gcgcgaatga tccgccgcgc cggtgtcctc ttcgaagtcg aaggcatcga
    14341 ccggactggt cttcgccccg tagggcaggc gtgcgaggaa tcgcggcatc gccaggccga
    14401 tgtagcgcgc gtcgtcggat tcgcgcagcg aacgccaggc agcgtactcc ggggtgagga
    14461 agatcttcgt gaggtcgcgc ggattggcga gctcctgcca ggaatccatc tgcatcaggg
    14521 tcgggctcgc ccccgcgatg aagggcgaat gcgcggccgc ggagaccttt gcgatctcgc
    14581 cgagcagttc gacgtcgggt gggctctggt cgaagtagta gtcgcccatc aggcagccga
    14641 aaggctcgcc gccgaactgg ccgtattctt cctcgtagat cttcttgaac accgggctct
    14701 ggtcccatgc ggtgcccttg aacttcttga gggtcttgcc gaggtccgcc ttggagatgt
    14761 tcatgacgcg gatcttgagc atctcgtcgg tctcggtgtt gttcaccagg taatgcagac
    14821 cgcgccaagc gccctcgagc ttctggaaat ccgggtggtg caggatgacg ttcacctgct
    14881 cggtcagctt gcggtcgagc tcggcgataa tcgcctcgat cgacttgacc acatccgggc
    14941 tgatcaccgt ggtgttcgcc agcgcctgct gcgccagcgt cagaacggcc tgctcgaccg
    15001 cgctgcgggc ctcgtcggtc ttgggcttga attccttctg cagcagcgag gcgagttcgt
    15061 cgccctcgag cgccacacca gcgagttggg tgctttgttg tacttcggcc atcgcaattc
    15121 tcctcgatcc gttctcgtgc gcgttcaggc gccgccgcct tcagccggct tgccttcgtc
    15181 tgccggcttc ggcgcggcgg ccagcgactg cagcagggcc gggtcctgga tgaccttggc
    15241 gatcagctcc tcggcgccac tcttgccgtc catgaaggtg atcaggttgg cgagctgctg
    15301 ccgggcctcg agcagcttgt tgagggcatc gaccttgccg gcgaccgcgg cgggcgaaaa
    15361 gtcgtccatg ctctcgaagg tgatctcgac attgaggttg ccctcgccgg tcagcgtgtt
    15421 cggcacctgg aaggcgaccc gcggcttcat cgccttcatg cggctatcga agttgtcgac
    15481 atcgatctcg aggaacttgc gctcgtccac cttgggcagc ggctcggccg gcttgcccga
    15541 aagatcggac agcaccccca tcacgaaggg cagctggatc ttcttctcgg cgccgtagag
    15601 ttcgacgtcg tattcgatct gcacccgcgg ggcgcggttg cgcgcgatga acttctggct
    15661 gctggtgacc acgtcggttc tccttgtcga gcggatgaaa cggtttgctg cgatcgtcgg
    15721 tgctcagtcc ttctgctccg ctccggcgat cgactcgatc tgcttgaggc tctcgggtgc
    15781 catgtcccgg atgatgtcca cgaaattcat gctgaccagc ctgcgcgccc gacggatcag
    15841 caagggcgcg ggattggtcg gttcattgcg ctcgaaatac tcgatgacgg tatcgagcat
    15901 cctcagcgcg tcgtcccggt tgcgaatctc gccgctcatc ccctcctccg tctgcggcgc
    15961 caaccgatcc gcatccacac ccctttccgc ccccccggcc ccggcctgcg tcgcctgcgc
    16021 aggcgccggc gcgacgcgcg cgcacacctg ctgcaccagg cccagcaagc ccagcaaggg
    16081 ggcgaaatcg accgcccgat cagcccccac ccgctcgacc agcgccgcgg cgagtgcccg
    16141 cgcactggcc agggtcttgc cgacgccggc ggcgattccg gggtcgtcca gcaccgcgtc
    16201 cgcgaacatc ctgtccacct gcgcttgcga gaacgcctgc tcgtcgggac gcgccggcat
    16261 cttccccgcg gccacctcga cgtcgcggac cttcaaaccg ccaccgaaac gcaccggcaa
    16321 caccatcgac gcacgcaggt ccttgagcaa ggcgcccgca tccaccagcg gggccagcgc
    16381 attcgatcga acgatcggat cgaagtcgtc atccggatcg agccggggat gaagcgcatc
    16441 ccaatagcgt tcgatcagtc ccctgattat ttctagtcca tactcgagcg cggagaaacc
    16501 ctcggttttg accaaggcac gcgcaagcag cacggccacg cgcagatcct tcgagcgcag
    16561 caacaaaccc tccgcggtgg cgcgcacctc gggccagcgc ggctcctgcg cgggaatgac
    16621 ggtatcgccg tactgttgcg cgatgcgctc ccgtgccgcc tcttccagcg cctggaatgc
    16681 ggggtcgtac tcgagatcgg gaccgcaggg tgggagctcg ggtgtttcgg cgagcagggc
    16741 gtctggatcg atcaagaggt cctccggaag aaggggcggc aagcgccgcc cgaagggttc
    16801 agaaatcgct gcacggattg cgttcatcca cgccgatgca gttggaaaga ttgggccgcg
    16861 agcgcacccg cgaccactcc atcgccagca gatcgccagc ctgcgcagcg ccagcgccga
    16921 tcaacggccc gcccgcaaag cacatcggcg gcaggccgaa gttgcgctca tgcacccgcg
    16981 aagactcgcc ggtcgggcgc agcaccgcgc cctgctccgg ccccggcgca cgcgccgtca
    17041 cggtcagcgc aacaaggttc tccagcgcct gctcgaaccg gtagttctgc gcgctcagcc
    17101 cgctgccctc gatcggatac gcgcccggag ggctgaactg tcccgccggg ctcgcgaaga
    17161 cgagcacgcc gctggtcgcc gtttcgagcg tgtcgcccac gacgaagcca ctgaccgaac
    17221 cgctcaatgg cggattcgga acgctgtagg ggcgcgtggc gggcgtagcg acataggtca
    17281 gggtcgcggg gtcgatcgcc agcgcctgcg cgttcgagct tgccgattcg atcaggtagt
    17341 tgcccgcgct cagcccgctc gccgtcaccg cataccgccc caccgcgctg cgctcggtcg
    17401 ccggcgtcgc cagggccagc gtgcccgtgg tggcgttggc cagcgagtcc tcgaacagaa
    17461 aaccactcac cgtcgcagag aacgccgggt tggccgcgcc gtagagacgc gacacgggat
    17521 cgaccgtgac cagcagtgtc gccgggtcga tggacagcgc ctgcgcgttc gagcttgccg
    17581 attcgatcag gtagttgccc gcgctcagcn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17701 nnnnnnnnnc agcgcctgcg cgttcgagct tgccgattcg atcaggtagt tgcccgcgct
    17761 cagcccgctc gccgtcaccg cataccgccc caccgcgctg cgctcggtcg ccggcgtcgc
    17821 cagggccagc gtgcccgtgg tggcgttggc cagcgtgtca cccagcacga agccgctcac
    17881 cgccgccgag aacgccgggt tggccgcacc atacaggcgc gacaccgggt cgacggtaac
    17941 cagcaaactt gccgggtcga tcgtcaagct gccctcgctg acatcgagca gataccctgc
    18001 cggtgacacc aggccgcccg acgagttgtc gatcgtatag tcgccgaccg gcgacccctg
    18061 gacggccgtc gttcccagcg caccggagag cacgtcggca gcgagatcac cattcaccag
    18121 gccatcgacc gcgggatcgt atcccagctc cggaatcgca tccccatagg tcaggcttgc
    18181 atcccgggcg aagatgctca gcgtcggctg cccctcgaag accatgagat tgcccgtcgc
    18241 cgggagcgtc acgccagtca cgcatccatc ggaaaaactg cagccataaa atcgggaagc
    18301 gtcatcggca aggtcaccga ggtctgccgc agtgccccag gtggacgccc acacctgcca
    18361 gcgaccaccg gtgccggggg tgagctcggc acccggcgcg gcgaagaacc tgccgtcggc
    18421 cacgagggtg atgttcgagt tggcatcgag cgtggtgatg ctctgcccca gggtgaggct
    18481 tccgttgatc gtctggacga aaaagtctcc gtaggcagag gagtcggcgg cagcaaggac
    18541 ctggaccgta ccacttgtgg tcgaataccc agggcccgac agcgggccga tgaccacggg
    18601 tccgtcgttg acgaaggcga acgatgccgg cgggtcgacg gccagggtgc cgacgctgtt
    18661 cgcatacttc gtcagatcga tgttcgcagc atccgtcgcg cgcacgagca aggcatcggc
    18721 cacgatcgaa ccacccgtcg cctggaccag cggaccggtg gacgccagga tcagcgtgtg
    18781 cccggacacc tccaggccgc cgaaattgat cccggaagat ccatcgcctt cgttctgcag
    18841 ggtcagatcg gcgttcagca tgaggccgga tgcagaggtg ctgatctgcc cggtatgggt
    18901 gtcgcttccg aacacgaccg aagcgacgtc ctcgatggcg gcgagatcgc gcggctcgat
    18961 ttcgaagccg ttccccgtgc tcgtacccac gccgatcggg accgcatccg cgcgcacggg
    19021 gtcacctccg ttcacccccc cgggaaccag taccaacgaa cccgcggtca ggatggatgc
    19081 cggctcggtg atgccatcgt cgaaataatg gagttcgatg ctgtccgtcg ctccaccatt
    19141 gcgggcacgg aggatgatgt cgccaagctg ggtctcgtca ccgccaccca gcaccacgtt
    19201 gcccagcgcc agccccagcc ccgaggtcgc ggtcgtgtca cccgtgatct cgagccgtcc
    19261 cgtgccggag cgcacggacg tctcctccgc gtcaagcgga ccgtatgaga ggcggacgcc
    19321 gatttcggtg ccgctcgagc cggcaatcgt gacatctcct ccacccgatg cgatcgaagt
    19381 ccggtagagg ttcaccgcgg cgtcgaagct gctctcgccg cgaatttcga cgccgctcgc
    19441 gccaaagatc tccgagttgc ctgcgggcga ctgctgcgaa ctggcaggaa catacacgcc
    19501 gtaggcgagc aagctcttgc caaagatgcc gacgcttccc gccttggact cgatcacgct
    19561 gcgctcgagc ttcacgccat catcgtcgtg cgtgttctcg ccgcgaagat cgacacctgc
    19621 aaaacccgag atcgtcgagt cgagcacatt cacgccatgg gagacgacct cgttcccttc
    19681 gcccaagccg atgatgttca cggcgcctag cgtcgcctcg accctgcttt ccgacaggcg
    19741 caccccgtcg tccgcggcgc tcgttccgtc gatgagcact ccccggccac cgaggatgcc
    19801 ggtccgcgag gactgcaccc cggcaccacc gatctctccg actccgtaga tcctcacagt
    19861 gccgcccggc gcttcgatcg tgttcgaata cgcgccggac tcctcgatca cgccctgcaa
    19921 gctcacgccc tcgcggccac cttccccgct cccacgaatc gaaatgtctc ccgcccctgt
    19981 gtcgatcgtc gaatcttcga tccgaacacc cgccagatcg acttcatcct cacggccaga
    20041 ggcgtaacca ttgtctgcgt cgccctgacc aaaaatgcgc agtgcgccgc cattcgtatc
    20101 gatgatcgcg ccgagaatcc ggactccccc cgtttccgca gctgcggtgt cggcgctaag
    20161 gtccacgtcc agtgagcccg ccccgaccgc ctcgatgcgg gcgccgggct cgatacggat
    20221 gtctcgatgt gcctcgagcg tcagcgatac acgcccgcca cccgtatata ggattgccgg
    20281 ggggtcctgc tccgtatccc tctccatcgt gatgtcgccg gcttcacctt cgacgtcggc
    20341 cgttccggta cgcaccacca cactggttcc ctggttgagc gcgttggaga taacgatggc
    20401 accaatgctg gcaggtgagc ccaccggaaa gaagaccggc cccgcttcct cttcgatgtt
    20461 gtcatttgca tcaccggcga cgatgcggag atcggtggga tccagcaacc actgacccgc
    20521 cttgcccgcg ggcgcggtcg cgctcacccg cgcaccgctc acatccagga agccacccga
    20581 ggtctcgacc acgccgccat cgccgcccgc cggaccacca cgcgcgctga agctgccatg
    20641 cgcacgcgtc gcttcgtcgc tccatgccac caccttgccg cccgtgccag ccaccgtcgc
    20701 atccgccttc acgctggccc tcggcccgac ataggccgcc ttcgcattgc gcaccgccgg
    20761 gttgcgcccc tggtagtcgc caccgacgag gactgctccc ccgcccgcgg cgccggaggc
    20821 atcgagcgcg gcagctccgc tcacggccac gtggtggccc agcacctgca cctcgcctcc
    20881 gcgtccgccc gcctgcggcg cgctcgcgtc cagcacaccc gacacctcgg tgacgcccga
    20941 gtcgccgccg tcgaggacga tgcgtccacc gcgctcgctg agcccgcggg cgcgcacgac
    21001 gccggtctgg ttgaccaccc gcgagctgac ctcggcgagg gcgcgcgcgc tgagcagcac
    21061 ctgcccgccg tcggcgatca cggcaccgcc gttggcgacg agggcatcga gcgtggctcg
    21121 cgtgacggtg aggcgggaca gtccgtcgcc ggccaggtcc agcgtcatct cctcgcccgc
    21181 agccatcgcg acggtgccga gctgcgcgcg gatcgtgccg ttgttggcca cccggccacc
    21241 catcagcgcc acggtgccgc gatcggcgac gctgatcgag ccggcgttct cgaccgcagc
    21301 cggcccctcc agcgcgcgga agcggagacg gtcggcgacg aagtcgtcgt tgtcgatgtc
    21361 gagcgtggag gccaccagcg accccacgtt caccgcggcc gtctcgccga acacgacgcc
    21421 gttgcgattg atcaggaaga ccttgccatt ggcgtccagg cggccctgaa tctcactgcg
    21481 cgaagcgccc gtcacccggt tgaggatggc gctgcccgcc cccggctgct cgatccgcac
    21541 ctgctcgccc gcgccgatcg agaagccctg ccagttgacg atggccttgt cgctcgcctg
    21601 ccggatcacc atgcgcgacg cgtcgggccg gcccacctcg accaccccgt gcgcagtggt
    21661 gttcccctcg gggagcgccc acgccggcca ggcctgggag aaggcgagcg caagcgccgc
    21721 cgcaagaatg cggggcgccg gtgcgcgacg atacgggcgg atcgttttca tggtgtcctc
    21781 ctgcagcatg ttcgggcagt cgcgaggctc agaacgcgtg cgtcagctgc acataaagac
    21841 gcggcacgcg gtctcgatcg acctcgccac gcgcgctggt acgccaggcc aggctggtgc
    21901 gcaacacggt gtcgcctgcg aggctccaga aggcgccgat gcccgcgccc cgcagcgaga
    21961 cgctgttgtc ggtcccgccc gaggcgtggc gatcggtgcg cccccagccc cagtcgtgga
    22021 atagctgcac ggacagctcc ggcgtgagcg cgcgacgaag ctcgagggtc gcgacgtggc
    22081 ccacatcgac cgtcgcctcg gagggcgcgt aggcacgcac cgcacgcggc ccgccgagcg
    22141 cgaccttttc cgcgctgtcg aggttgcggc tggcgaactg cccgctgatg gcgaaataga
    22201 gcgaggtctt gtccatcaac gcattgagtc gcgacagccc gtaggtccag cgggtgaagt
    22261 tcccggcact gcggcgtccc gcctgatcga gcgcaagcgc atcgggatcg agccgcagtc
    22321 gaccgcggta aagggtcagt tcggcgctca tgtaaccgcc acccagccag tcgtcgcgtt
    22381 gctcgtagtt caagcccgca tggaaactgc gcagcttctt gtcctcgctg aagccgacgg
    22441 catccaggcg atcgtctagc cgcttctcct gccagcccag ccgaccgaac aggttgcgcg
    22501 cgcgcgagcg cacgaagggg tgggtgagcc cgacctcgac cagatcggcc tcaccgctgg
    22561 cgtctagtgc ggcgaagtcc tggccgagtt cgtactccac ccgcgcgacc gacacgccga
    22621 atcgcgtccc ctgcccgccc accggcagct cgtagccgac acggccatac gccaggcggc
    22681 cacccgtgcc gaactgcagg cgcacgtcga ggttgtcgcc gagacgcagc ggaccgttga
    22741 tgcgtccgag caagccggca cggtactcgg aagtgctgcg cgagccatgg ttatcgacat
    22801 cgaccatcag gtcccagcgc cggcgtggcg cgacatcgag caccagatcc acgctacccg
    22861 gttccaggcc cggctcgagc gcggcctccg gccgcaggcc cggcaggtcc gacagcagca
    22921 acatcgtgcg ctcgaggtcg gcgccgcgca gcggctcccc acccggcagg cccgccgtga
    22981 tgccacggat caccgcctcg cgaaccggcg ccaccggatc gaccgtggct cgtaccgcac
    23041 ccatccgccc ttcgatcacc gaaagctcga cccgcccatc gtcgatcgcc tgcaccggga
    23101 cgatcgcctc ggccagcagg aatcccgcgt cgcgatagcg cgcgctcacc tgcgccgcga
    23161 tcgcctgcag gtcggcgaaa gtcacctcct tccccagcca cggcgccacc tcggcctgca
    23221 gctgcgcatc cgcgaaggcg gtgttgccgg agaaacgcac cgagcgcagc acgaaggacg
    23281 ggcctcccgc cgcggcgggc gcgggcgccg cacgctcggg cagcagcggt gcctgttcgg
    23341 ttcccggcag gacccgctcg ggggggctgg cctcgcgcaa tacatccccc gcccccggcg
    23401 gcatctgtgc ccccgagggc ggagtcgcgg ccagcacggc ccccacgacc aggcaggcgc
    23461 gcaggccgta cacgttcgaa ccgctcgatc gggctgtttt catgatccgg aacgctccat
    23521 ggagtggacg gcgatgcggg acaggctcag gtgccgccac gcagacgcca gtcaccgatg
    23581 aggttgaacg gcgcccagaa gaacgggtgc gcaaacccgg cctgccgcaa ggtggcgacc
    23641 tgtgcctcgc gcatcgcctc cacggcggcg gtcccgcgca cgaaggctgc atagaaacgc
    23701 gtcatcagga actcggtgga atcgtcggcc accggccaca gcgaggcgac caggcctccc
    23761 gcccctgcgg tcaggaaggc acgcgtgaag ccgagaatct cgtcgccgcg ggcgatgcgg
    23821 cccagcccgc tctcgcaggc cgagagcgtg accagcgaca caccgccgag gtcgacctcg
    23881 tagacctcac gtgcctcgag gaagcctgga tcgtcggctg cgccggcgag caggatgcgc
    23941 gagtgcaggg gatcgaccgc atcgacctcg gcatgcgctg ccacgtgcag gatgcgtccc
    24001 gcaccagcgc tctcgcggaa gcgctccttg gacgcctgct cgcggaaata caccctgcgc
    24061 tcgggaaaca ggtcgctgat ccgctcgacc tcgcgctccg cgccgggaag tccctcgcgc
    24121 gcctggttcg cggggttgcc gaaggccacc agcgcaccgg ctgcgcccgc accccggcgt
    24181 gccagttgca gggccacgct cgccgacgga gcgatcacga tgccgcgctc ctcgatcagg
    24241 tagcgcccct cggtgcccac aagcgcctgg aaaggcagat agtgcagcgc accatgcggg
    24301 accacgacca ggcgttcgga tccggacggc aggccgagcg gctcgacgat gcgggcatgg
    24361 agggcacgcg cgagcgtccg ggtgtcgcct gcgcgcctga agatcgaccg gcgaaattcg
    24421 tccacgatgg cctcgagatc gcggcgggcg atcggcagca cctccccccg cagcatgccc
    24481 ggcgcgacca cccaggcgac gagccggtct tcgagcgcgt ggtactgcac cagcaactcg
    24541 ccgggcagca gcgcggcttg cagctcggcc aagcccacgg cgcccaccgc tgcatcgata
    24601 cgacctcccc cgtcgacccg gccgcgcagg gtgtcgagca gcgcgcgccc ccggctgcgc
    24661 tcggaaagcg cccaggcacg ttcggtctcg ccgagctcca tcgacagcgc gaccgcgagc
    24721 tcgaacacct gctgcatgtc gccgaacagg ccggtcttga actcctcgct gcgaaaacgc
    24781 gcacgtacgc cttcggcgag cgtcgcggcc tccagcgcac gccgctgtgc ttcgcggcgg
    24841 tcgccgcgtg cgagccaggt gcgcgccagg ccatcgagcg cccacaggcg gttgtagtcc
    24901 gcatccgcac cggcggcacc acgggcggcc gactcgaatg cggccgcggc ttcgtcgaca
    24961 cgcccctctg cgagcagcag gcgcccttcg atgcgcgcac gcagcggggc cagcgctggc
    25021 tctgcagctg cctgccgctc gaacaccgca cgcgcctcgc cgctgcgacc ggcgctcaag
    25081 tacgcattga ccagggacag atcgaccagc gcgcggaagc gctcgctcgc cacctcggcc
    25141 gccttgccgt acaagccgat cgcctcatcg tggcgcccgc gtcgcgtcgc gacatcgccg
    25201 agcgtcttgt atgccggccc ggcgacgatg gcaggattct tcgccacatg ctggagcgct
    25261 tcacgcgcgt gccgctcggc actgtccagg tcgcccgcgt agctgtatgc gatcgcgaaa
    25321 tcgcgtttgg cgagcgcaac gagatcctcg tttccctcgg ccagccccac atgcaaggta
    25381 cgcgccgcag agcggatgct ttcgcgcagt tcgccacgct cggcctggct cacggcctgg
    25441 ctgcagtaac gataaccgtc gagccgtaca cgatcgcggc gatacagcaa ctgcccctcc
    25501 gccgtgagcg ccttcaaggt ctctgcgtcg cgcagccgtg cctgcgcact gtcgaacacc
    25561 accgccccgc cgcccgcgac ggcctgagcg aacaccgaag gccccgttcc ccacaccagg
    25621 cacagggcca ggaccgctgc cgcatgccgc actctcgccc gcatcgtcga catgactacc
    25681 cccttctcgc cactgctggg aaaccattca cggacagggg cgcacgcgtg ctgcgcccgc
    25741 aggaaagcct tcgcacacca ccccgccggt aaccgtccga aagcggacgg ttcgatacag
    25801 aacttccatc ctcgagcccg acgagcgaag agtccgcgca cacgagcggg cgcgctccct
    25861 tgatttcaat ctagccaaac gtgccgcgct tgcaagccga atatgccctg cgccagcgcc
    25921 cgcggcacgg cgtcgagtcg cgcccgacgc cgaggatgcg ggtgataaac tgggactttc
    25981 cattccttcg ccagcctacg tcatgctctc cgaacagctc cgcgtcgaaa tccagcgcaa
    26041 catcgcagcc tcgctcgccg aggacatcgg caccggcgat ctcaccgccc gcctgatcgc
    26101 cccggacacc gaagcgcgcg gccgggtcat cacccgcgag gacgcggtcg tctgcggcac
    26161 cgcctggttc gacgccgcct tcgccgcgct cagccccgcg gcggtggtgc actggcacgt
    26221 caaggacggc gacagcgtga cggccggcca gaccctgtgc gagatcgccg cgcgcgcgcg
    26281 cgtgctgctc accgccgaac gcaccgcgct caacttcctg caactgctct cgggcaccgc
    26341 caccgtcacc cgccgcttcg tcgatgcggt ggccggcacc cgcgccagga tcgtcgacac
    26401 ccgcaagacc ctgcccggcc tgcgcctggc gcagaaatac gcggtcgcga tcggcggcgg
    26461 caccaaccac cgcgtcggcc tctacgacgg catcctggtc aaggagaacc acatcatcgc
    26521 ggccggcggc atccgcgagg tcgtggagca ggcgcgcacg atcgcgccct ccaacgtgtt
    26581 catcgaggtc gaggtggaga cgctcgagca gatgcgcgag gcgctcgagg ccggcgtgaa
    26641 gatgatcctg ctcgacaaca tgacgctcga gcagatgcgc gaggccgtgg ccatcaacgc
    26701 cggccgcgcc gaactcgagg cctccggcgg cgtcaacctc gagcgcgtgc gcgcgatcgc
    26761 cgagaccggc gtcgaccgca tctcgatcgg caccctcacc aaggacgtgc gcgcgctgga
    26821 cctgtcgctg cgccacgtcg agcgctgagc gcgcggtccc ggatggctgc cagcacttcc
    26881 cggcctgcgg ccgtgccgca agccctgccc gactggccca tggtgccggc ctgccacggc
    26941 tggctcgcgc tcgacgcgcg cggctgctgg cggctgcgcg gcgagaccat cacccacccc
    27001 ggcctgatcg cgttcctcgc cgcccattac accgcggacg cgcgcggcaa ctggctggtg
    27061 aataacggcc cccagcgggt ctatgtcgag ctcgccgcgg cgccgctgat cctgcgcctg
    27121 catcccggcg gccgcctcgt gacccacagc ggacgcgagg cgcgtgcgac cggcccggtg
    27181 ctggtcgacg cggagggctg cgccttcctc gccaccgacc tgggccccgg gatgatcgac
    27241 gaccgcgacc tcgcgctctt tgccgccgaa ctgcagcatg tcgatggcgc gccggccgga
    27301 gacgaggccc tgctcgcact gatcgacgga cagcccgatc ctgaactgcg ttggcgcgat
    27361 ctcgatgtcg tctcctgcgc gcgcgcggag atccccgaac gcctcggctt ccagccccgc
    27421 ccgcaagccc tcgagccctg aacggcgacg ccagcgtcca ccatggcatc ggcacccgcg
    27481 cttggcgctc gcatcggctg cagcagctgt tgacccgcgc cgcgcttcaa ggctatgatc
    27541 cgcgcccttg ctcgatgcgg acggcgccaa ggcaccgcaa accgcagcag cgaagccttg
    27601 gtggtgaaat tggtagacac gctatcttga gggggtagtg gcgaaagccg tgcgagttcg
    27661 agtctcgccc aaggcaccag attccggccc cgccgacgac tacggcgccc gacaaaaaag
    27721 cccgcgatgc gttcgcgggc ttttttcgtt cacgtcccga cctccccgcc ggccgctcgc
    27781 cgacggggag gcgacgatca ggtgcgcgcc gcgatgaagc gcttgatcgc gtccgtgtcg
    27841 ggcgccatca cctcgacgcg ctgcggcagc ttctcgatgc cctcgaggtc ggcgggacgc
    27901 tccggctcgc ggcccagcgc ctcgacgatg gtctcggcga acttcaccgg cagcgcggtc
    27961 tccagcacca gcaccggcac gcccgcgggt accgcggcag cgtgcgccca ggccaccttg
    28021 acgccgtcgg cggtgtgggt gtcgatgatc acgccgtact gctcgtacac cctgcggatg
    28081 gtcgccaggc ggtcggcgtg gctgctcgcg ccggacacga agccgaacgc gccgatgcgg
    28141 gcgaattcgt ccgtgcccga caggtcgaag gcgcgcccgg catcgacctc ggcccacagc
    28201 gcggccacct ttttcgggtc gcggccaacc aggtcgaaga cgaagcgctc gaagttcgag
    28261 gccttggaga tgtccatcga cgggctggac gtcacgtgcg tctcggcggc cttgcgcggg
    28321 cgatacacgc cgctgtggaa gaactcgtcg agcacgtcgt tctcgttggt ggcgaggatc
    28381 agcttcgcca ccggcaggcc catctggcgg gcgatgtggc cggcgcagat gttgccgaaa
    28441 ttgcccgagg gtacgcagaa ggcgacctgc tcgtcgttgc tcttcgtcgc cgcgaagtag
    28501 cccttgaagt aatagacgat ctgcgccgcg acccgcgccc agttgatcga attgaccgcg
    28561 ccgatcttgt gcgcggcctt gaaggcgtgg tcgttggaga ccgccttcac gatgtcctgg
    28621 gcgtcgtcga acatgccggt gacggcgatg ttgaagatgt tgtcgtcctg cagcgaatac
    28681 atctgcgcgc gctggaaggc actcatcttg ccgtgcggcg acagcatgaa cacgcgcacc
    28741 ccgtgcttgc cgcgcatcgc gtactcggcc gcggagccgg tgtcgcccga ggtggcgccg
    28801 aggatgttga tggtctcgcc gcgcttcgcg agcacgtact cgaacaggtt gccgagcagc
    28861 tgcatcgcca tgtccttgaa ggcgagcgtg ggcccgttgg acagttcgag caggccgagc
    28921 cgcccttcct cgagccagtg caccggggtg atgtcgctcg cccggtcgcc tttgcgcaca
    28981 tggcgataga cctcggcggt gtaggtcttg tcgcagatcg ccttcaggtc ggcggcgggg
    29041 atgtcggtga tgaacctgga caggatcgcg aacgccagct cggcatagga caggctccgc
    29101 caggcatcga gctcggcgcg cgtcacctgc gggtaggtct cgggcaggta gaggccgccg
    29161 tcgggggcga ggccgccgag caggatgtcg cagaactccg ggttggcggg ctggccggcg
    29221 tggccgcggg tggagagata cttcacgtgg gcagtccttc agggtgacgt ggtcggcgcg
    29281 cgccgtccgg cgcgaagccg ggattctaac gaattcggcg gacgaattcg gcggacgcat
    29341 gtgcgccgaa caaggccgga gagcccgatg gcggcggccg cggcggccgt gcaagtcgga
    29401 ctgcaagcgc gcacccgaga tgggcaagcc ggctgaatat gccgcacgcc cacgcgccgc
    29461 acaccgatac aatggaattt ccacaacgaa cgggagtccg ccatgaacct cggaaacatc
    29521 ctcggtcaga tccttcagca aggcatgggc cagcagggcc gttcccgcct cgaccacgcc
    29581 atgggtccgg gcggcatggc agacgtgctc ggcggcctcc tcggcggcag cggtccggcg
    29641 ggtggcgcgg gtggcggcct cggaggcggg ctcggcgatc tgctcggcga tctgctcggc
    29701 ggggtgctcg gcggcggccg tggcggttcc acagcgggcg gcatgggaga cctgggcgag
    29761 atcctcggcg gcgcgctcgg tggcggccgc gccacgagcg gcggtggcgg gctgggcgat
    29821 ctgctcgggg ggctgctcgg cggcggcgcc gcgggcagca cgggtgcacg cagcggcggc
    29881 aatgccggca tggccatcct cgccacgatc gcgatggcgg cgctgaagaa ctggaccgac
    29941 aatcgccgcg cgcaggccgc gatggcgccc gacacggcgg gcttcgccac acccgagctg
    30001 gaagccatga ccgcccccgc caccgaggag ctcgtcgtgc gcgcgatgat ctcggcggcc
    30061 aaggccgacg gcgaggtcgg cgaggacgag atccagcgca tcgtcggccg cgtgggcgcc
    30121 gacggcctga gcgaggagga gaagcagttc atgatcgccg agctgcgtcg cccgctcgac
    30181 ctcgccgcgc tcgtcgccga ggtgcccaac gagatggtgg cggccgaggt ctatgccgcc
    30241 tcgctactcg cgatccagct cgacaccccg gccgaggccg cctacctgcg ccagctcgcc
    30301 caggcgctgc ggctggatgg tgcgacgctg tcccgcctgc acgagatcac cggggcaagc
    30361 gcggtctgag caactcgaac gaaccgcgcc gccgcagggc aaggcggcgc ggcggcgccc
    30421 cccgctactc gctctcgagg cggaagccga tcttcagggt gacctggaag tgcgccacct
    30481 tgccgtcgac cacatggcca cgcgtctcca ccacctcgaa ccagtcgata tggcggatcg
    30541 tgcgggacgc ggtctcgatc gcattgcgga tggcggcgtc ggtgccctcg tgcgaggtgc
    30601 cgacgacttc gacgagcttg tagacgcgat cggacatctt gttctccttg gtggtgccgg
    30661 ccggcgccgg caggctgctc agtctgcgcc cggttccgcg cgcgggccat cgccgcgcaa
    30721 cctgttcgca gcctcgaagc ggcgcacggc cgccgtgtag ccacggacgc cgagcacggc
    30781 gatcgcgatc aggatggcgg cgaagacgat gagcttgaag accatgcgaa gactgcctgc
    30841 tggcgagggt cgggatcgcg gcacgcgcgg cgtgcacgcc gcacgtgctt cagtctaggc
    30901 gcaaacgccc gcgctgtcgc gcgcgcccgc ggcctccccg cgagcgctct cctgcgtcat
    30961 cctgttctca gctcgcgtgc gcgcgcagcc acgccgcgcg ctcgcgccag cgcgtcgcct
    31021 tgtcggcggc aagcccgggc gcgccggcga tgcgatcgag cagcacggcg tcgggccggt
    31081 gcgcggtcac cgcgtcccag tagtcggcga gcgtgagcca ggggttgggg cgctcgagca
    31141 gctcgatcgt gtcgccggcg gcgatcaggc ccggctccag cacccggtag taccagccgg
    31201 tgatccccgc cgcctcgacg aagcgcgagg cgccgtcgac cttcaggcgc aggtcgatct
    31261 tccagcacgg cgagcgcgtc tggctcacct gcacgcgcgc ctcgccgatg cgcagcacgt
    31321 cgccgatgca cagcgcgtgc tcgtccagcc cgtgcgtgct gatgttctcg ccgaggaagc
    31381 ccgcacccac cgcggccgca cattgcggcc actcggcggc gagcaccgcg tagtgctcga
    31441 ccgggtagtg gtgcagggcc ttgtccaccc cgccgtggtg gcgcaggtcg gcctgctcgt
    31501 cgccctccag cccggtcggc gtcagcatca ccggtcccgc tgcgggcgac ttgacgatac
    31561 cgctgcgctc gccttcgatc gacagcaggc gcaccttgcc gacgaagacc tcatccacct
    31621 tgttctgcat gaccgcaatc ccccttgcca ccaccgcgcc ccggtacgca cccgcgctgg
    31681 gcgtaaacgc acgaggccgc acccgggggc gcggcctcgc cttcaatcac gactcgagcc
    31741 cgcgctcaga gcgtttccat gcgcagcttc accaccttgc cctgcaccac cggcagcgcc
    31801 tcgatgcgcg cgattgcggc gttggcgttc ttctccgcgg tctggtgggt cagcatgatg
    31861 atgtcggtgt gcgcctcgcc ctcggccgcc tccttctgga tcagcgcctc gatcgagatg
    31921 ctgctgtcgg cgaggatgcg ggtgatgtcg gcgagcacgc ccggcttgtc ctcgacgcgc
    31981 atgcgcaggt agtaggaggt gacgacctcc tcgatcggca gcaccggcac gtcgtgcacc
    32041 tgatcgggct ggaaggccag gtggggcacg cggtgctcgg gatcggaggt gtgcaggcgg
    32101 gtgacgtcga ccagatcggc gatcaccgcc gaggcggtgg gttcggcgcc cgcgcccttg
    32161 ccgtagtaaa gcgtcgcgcc gacggcgtcg ccctgcacca ggacggcgtt catcgcgccc
    32221 tcgacgttgg cgatgaggcg cttctccggg atcagcgtgg ggtgcacgcg cagttcgacg
    32281 ccattctcgc ggcggcgggc gatgccgagc agcttgatgc ggtagccgag ctgttcggca
    32341 tagccgatgt ccaccgagtc gagcttgctg atgccctcga tgtaggcctt gtcgaactgc
    32401 atcgggatgc cgaaggcgat cgcgctcatg atcgtcgcct tgtgcgcggc gtcgacaccc
    32461 tcgacgtcga aggtcgggtc ggcctcggca tagccgagcg cctgcgcttc cttcaacacc
    32521 tcggcgaagg gcaggccctt gtcgcgcatc tcggacagga tgaagttggt ggtgccgttg
    32581 atgatgccgg ccagccactc gatgcggttg gcggtgaggc cctcgcgcag cgccttgatg
    32641 atcgggatgc cgccggccac cgcggcctcg aaggccacca tcacgccctt cttctgcgcc
    32701 gcggcgaaga tctcgttgcc atgcaccgcg agcagtgcct tgttggcggt gacgacgtgc
    32761 ttgccgttct cgatcgcctt cagcaccagc tccttggcca cgccatagcc gccgatcagc
    32821 tcgacgacga tgtcgatacc cggatcggtc accaccgaga aggcatcgtc ggtgagcttg
    32881 acctcgccac cggtgacctg gcgcgcgagc gcgagattct tatcggccac ggtgacgatg
    32941 cggatcggac ggcccgcgcg ccgggtgatc tcctcggcgt tgcgcttgag gacggtgtag
    33001 gtgccgccac cgacggtacc gatgccaagg aggccaacgt tgataggttt cattttgtcc
    33061 gtgaggtgtg aggtgtcaga ggtgaggggc aggcggcgcg gccgccttcc ggtgagggct
    33121 caggtgccgt ggcgcttgcg gtaggtttcg aggaagcgcg cgatgcggcc gatggcgtcg
    33181 cgcaggtcgt cctcgtgggg caggaagacc aggcggaagt ggtcgggatg cggccagttg
    33241 aagccggagc cctgcaccag cagcacgcgc tcctcctcga gcagttcggc gatgaaggcc
    33301 tggtcgtcct cgatcggata gaccttgggg tccaggcgcg ggaacatgta cagcgtggcc
    33361 tgcggcttca cgcagctcac gcccgggatc tgattgatga gctcccaggc gaggtcgcgc
    33421 tggcggcgca tgcgcccgcc ctctgcgacc aggtcgtcga tgctctggta gccgccgagc
    33481 gcggtctgga tcgcgtactg gccgggcacg ttggcgcaca ggcgcatcga ggccagcatg
    33541 ttcagcccct cgatgtagtc gttggcgcgg cgcttgtcgc cgcacaccac catccagccc
    33601 gcgcggtagc cgcaggaacg gtagttcttc gacaagccgt tgaagatgat cgtgagcacg
    33661 tcttcggaca gcgccgccat cgaggtgtgc ttgacgccct cgtagaggac cttgtcgtag
    33721 acctcgtcgg cgtagaggat caggtcgtgc tcgcgggcga gcgcgatgat ctgcttcagc
    33781 gtctcgtccg gatacaccgc gcccgtcggg ttgttcgggt tgatcaccac gatcgcacgc
    33841 gtgttcgcgt tgatcttcgc gcgcatgtcg tcgatgtccg gcagccagcc cttggactcg
    33901 tcgcacaggt aatgcaccgg cttgccgccc gacaggctca ccgccgcggt ccacagcggg
    33961 tagtcgggcg ccggcaccag cacctcgtcg ccggcgtcga gcagcgcgtt cattgccatc
    34021 acgatcagct cggacacccc gttgccgatg tagatgtcct cgatgccaac gcccttgatg
    34081 cccttctgct gggtgtagtg catcaccgcc ttgcgcgcgg agaagatgcc cttggaatcc
    34141 gaatagcccg ccgcgttggg caggttgcgg atcatgtcca tctggatctc ttcgggcgag
    34201 tcgaagccga acgcggcgag gttgccgatg ttgagcttga tgatcttgtg gccttcgtcc
    34261 tccatctgct tggcgcgcac cagcaccggg ccgcggatgt cgtagcagac ttcggcgagc
    34321 ttggcggact tgcggatcgg gcgcggcgcc gcggctgcgc ccgcctcggc cttgatcacc
    34381 ggttcggggg atgccgtcgc gagctcgagg gtcttcaccg ctttcatgcc agtccttcct
    34441 gagagatgga gaagcgccgg gagttttccc gcacgccaaa aggttgttat cttagccgcg
    34501 ctcccgcact gcggcaattt gcccggccat cgcgggcagc ccgccggcgt gcgccgcatg
    34561 ccgcgaccag gaacggatcg gatgaagctc tatcaggaca accacgccaa caccaacgtg
    34621 atcaccggct acggcgacga ccacgtgatg atcagcaaga cccgccacga gggcaacgtg
    34681 ctcgtcagcg ccagccaggt cgtggccggc tgggccccgc aggccggcgg cgacctcgcc
    34741 ggcctgacgg cggcggatct cgctcgcgcg gccgagctcg gcgccgagat cctcatcgtc
    34801 ggcaccggcc gccgccagcg cttcccccag ccaccactgc tgcgcgggct ggtggaggcg
    34861 cgcgtcggct tcgagttcat ggacttcgcc gccgcctgcc gcacctacaa catcctcgtg
    34921 gccgaaggcc gcgcggtggt gctcgggctg ctgcacgatc gctgagcacc gcaacgcggc
    34981 ggtaacgccg ccgcaatacg ctcttcaccc gggccggcgc tttcggctac cctgaggcgc
    35041 acgacacacg tgcgccggtg cgctcgcccc gagcgcgaag cgccgccgcc ccgacgaaca
    35101 ggagattcga ttgagcgccc ccctcgcccc cgacttcacc ctgcacgcca ccggcggcca
    35161 gaccgtcacc ctctccgcgc tgcgcggccg caagctcgtg atctacttct accccaagga
    35221 caacacgccc ggctgcacca acgagacacg cgacttcggc gcgctgcaag gcgagttcgc
    35281 cgccgccggc tgcaccatcc tcggcatcag ccgcgacagc ctcaagagcc acgagaactt
    35341 caaagccaag ctcgagctgc ccttcgagct cgcctccgat cccgaagaaa cggcctgcga
    35401 ggccttcggc gtcatgaagc tgaagaacat gtacggcaag caggtgcgcg gcatcgagcg
    35461 cagcaccttc ctgatcgacg ccgagggcac gatcgcgcgc gaatggcgcg gcgtgaaggt
    35521 gcccggccac gccgaggaag tgctcgccgc cgcacgcgcg ctctgacccc gccgccgggc
    35581 ggacgcgcgc acgcggcgca gttcgtccgg cacccatggc gcccgcgggc gccgcctctt
    35641 cccgcggccg tcctgccgcc ctcccggatc cgcacgccat gcccgtcacc cgccaatccg
    35701 ccgcccccgc gtccagcccc gcggatgcgg gcgcacccgc tgccaggcgc gtccgtcgca
    35761 gccgcaaggc cgcggccgcg agcaagctct tcgtgctcga caccaacgtg ctgatgcacg
    35821 accccaccag cctgtatcgc ttcgaggagc acgacctcta cgtgccgatc atgacgctgg
    35881 aggaactcga caacaacaag aagggcacca gcgaggtggc gcgcaacgcc cgccaggcca
    35941 gccgcatgct cgacgagatc gtgtccgcct ccgagaacgg catcgccgca ggcatcgcgc
    36001 tcgagagccc ctcgcgcggc ctcgccaccg ggcgcctgca cctgcagacc gaggcgatcg
    36061 acatccgcct gccgcccgcg ctgcctaccg cgcgcggcga caaccagatc ctcgccgtgg
    36121 tgatgttcct ggtggagaag cacccggggc gcgacgtcat cctggtgtcg aaagacatca
    36181 acatgcgcat caaggcgcgc gcgctgggcc tcgccgcaca ggactacttc aacgacaagg
    36241 tgctcgagga cagcgacctg ctgtacaccg gcacccgcga gctgcccgcc gacttctggg
    36301 agacccacgc ccgcggcatg cagtcgtgga aggaggaggg ccgcagctac taccgcgtca
    36361 gcggtccgct cgccgccgag atgctggtca acgagttcgt ctatcaggac ggcgacagcc
    36421 cgctgcaggc ctgggtgaag gaacaggaag gccgtggcgc cctcatcgag accctcaccg
    36481 actacagcca caacaagaac aacgtctggg gcatcaccgc gcgcaaccgc gagcagaact
    36541 tcgcgctcaa cctgctgatg aaccccgaga tcgacttcgt caccctgctc ggccaggccg
    36601 gcaccggcaa gaccctgctg acgctcgccg ccgggctcac ccaggtgctc gagtccaagc
    36661 gctacaccga gatcatcatg acccgcgtca ccgtgccggt gggcgaggac atcggcttcc
    36721 tgccgggcac cgaggaagag aagatggcgc cgtggatggg cgcgctcgag gacaacctcg
    36781 acgtgctcaa cggcaccgcc ggcgagggcg gcgactgggg ccgcgcggcc acccgcgacc
    36841 tcatccgcag ccgcatcaag atcaagagcc tgaacttcat gcgcgggcgc accttcctca
    36901 acaagttcct catcatcgac gaggcgcaga acctcacgcc caagcagatg aagaccctga
    36961 tcacccgcgc cggtcccggc accaaggtgg tgtgcatggg caacatcgcg cagatcgaca
    37021 cgccctacct caccgagggc tcgtcgggcc tcaccttcgt ggtcgaccgc ttcaagggct
    37081 ggccgcactc gggccacatc accctgcagc gcggcgaacg ctcccgcctc gccgaccacg
    37141 ccgccgaggt gctctgacgc accccgcgca ggagcgccga caggcgcgaa tgcggcgcgc
    37201 tcgcctataa tgttcagatc gcttcgatca cggtctgccc atgagcaacg acgccgccac
    37261 cctgctggtg ggagccagca cggacttcct gcgcaacttc tcgcccttca accgcatgga
    37321 ggccgaggcg ctcggctttc tcgccgagcg cgcggtgctc gccttccacg cccgcggcag
    37381 cgagatcctg acgcccgagt cgggtgtgcc gacgcacttc cacatcgtcc agcgcggcaa
    37441 gatccaggcc cgccaggccg ggcaggccac cgtcaccgaa tacaccagcc tcaccctggg
    37501 gccgggcgaa tgcttcccga tcggcgcgat ctccgctcgt cgcccctcga ccaacgccta
    37561 cgtggcggtc gaggacagct tctgcttcca gatcagcgcc gacgacttcc tgcacctgat
    37621 gcagatcagc ccggtgttcc accttttctg cacgcaatac atcgccagcc tgctcagcca
    37681 gtcgcgccag cagctgcaga gcagcttcgc ccagcgcgcc gccgagcagc agacgatgac
    37741 cacggcgctc ggcaagctga tcaagcagga cccggtcttc gtcacccccg acacccccac
    37801 ccgcagcgcg ctcgagcgca tgtccgagct gcacctcggc tgcatggtgg tggtcgacgc
    37861 ggagcgccat ccggtcggca tcctgaccca gagcgacctg ctgccgcgcg tcatcctcgc
    37921 cggcttcgac ctcgcgcgcc cgatcggcga gctgatgacc gccaacccgc accagctgcc
    37981 ggcgagcgcc tcggcctacg acgccgtact cgagatggcc acccacggcg tgcgccacct
    38041 gctggtggtc gactccgaga gtgtgctgct cggcgtggtc tccgagcgcg acctcttctc
    38101 gctgcagcgc atcagcctgc gccagatccg cgccggcatc gacaacgccg ccgacatcgc
    38161 ggccctgcag cgcgcgagca aggacatccg ccaactcgcc ctcaacctca tcgcccaggg
    38221 catcggcgcc gagcagctca cccagttcat ctcggcgctc aacgacgccc tcacccgccg
    38281 catcatcacg ctggcgcgcg agcaccacga tctggtgggc atcgacttcg cgtggttcgc
    38341 cttcggctcc gagggccgcc acgagcagac gctgtccacc gaccaggaca acgggatcat
    38401 cttccgctgc gcggacgcga agcaggtcaa ggagacgcgc acccgcctgg tcgagttcgc
    38461 acgcacggtc aacgaagacc tcgccgcctg cggcttcccg ctgtgcaagg gcaacatcat
    38521 ggcgagcaac cccgagctct gcctgaccct cgacgagtgg aagtcgcgct tcggcgactg
    38581 gatccgcgaa cccgacccgc aggccctgct caacgcctcg atcttcttcg atttccgcgt
    38641 gctctacggc aacgaacgct tcggcgacca gctgcgcagc gcgctcaaca agggcgccaa
    38701 gggcaacagc gccttcctgc gcatgatggc cgccaacgcg ctcaaggtca tgccgccgct
    38761 cggccgcatc cgcgacttcg tggtcgagga agacggcacc atcgacctga agaagtcggg
    38821 cgcccgcctc ttcgtcgacg tggcgcgcat cctggcgctg cgcaccggcg tggagtcgag
    38881 cagcacggtg cagcgcctgc gccagggcag caacaagatc ggcatgagcc cggaagaggt
    38941 ctcggccatc atcgacggct tcaacttcat ccagctgctg cgcctgcgct cgcagcacct
    39001 cgagaccgag cacgactccg ccgacgacaa ccgcatcgac cccgaatcgc tcaacgaact
    39061 cgaccgccgc atcctcaagg aagcattccg ccaggcgcgc aagctccagc tgcggctcaa
    39121 actcgactat caactatgag ctggctctcc cgcctcaaga tcgcccgcgg caaccagccg
    39181 ccgctgagcg ccgaagccga gcgtgcgctc gaggcctggc aagcgctcgc cgaagccggg
    39241 cacgaacagc cgcatttcga gtcgcgctac atcgtgctca acaccgaggc caccggcctc
    39301 gacctcgagc gcgaccgcct gctcgccgtc ggcgccatcg ccatcgacgg cggcctgctg
    39361 cacccgcggg acgcctacca cgcccagctc gagccctcgc ccggcgatgc gctcgccggc
    39421 ctgctcgcct tcgtcggccg cagtccgctg gtggtcttca acgccacctt caaccgcacc
    39481 atcctcgagc gcgccttcgc gagacagctc ggcttcacgc ccgagttcct gtggatcgac
    39541 ctctacttcc tgctgccctc gctgttcccc gagcgcctgg aacgtcccgg gcggctcgcc
    39601 gactggatgg cggccttcga gatcgagacc ttccagcgcc accacgccct cggggacgcc
    39661 tgggcgatcg cgcagctgtt cctggctgcg cagtcgcgcg cactctcgct cgcggtgacc
    39721 aatccacgcg cgctcgccga gcacgcccag gcctaccggc agaagctcaa ggtctgaagc
    39781 ggtatgccga tagaaagcgg aaggcctgcg cccgagcggc gcagatttcc ctttacaccg
    39841 gacgactcga tgcgtatatt cccgcgaatg tttttccggc catcccttct gatcctgctc
    39901 gccgcactcg cgctcgccca tcccgcccac gccgcggaac cggtcgtcgc gacggtcgaa
    39961 cacggcgcca aggtgccgtc cacgttcgac gagtacacca cggcggcaga gcagctggtc
    40021 gatgaggcgc tgtcctatct cggcatccgc tatcgcttcg gcgggacctc gccggcgacc
    40081 ggcttcgact gcagcgggct ggtgctcaac gtcttccgca acgccgtagg cctcgacctg
    40141 ccccgcaccg cgagcgagat ggccagcgta ggcgacaaga tcggcaagaa ggacctgaaa
    40201 ccgggcgacc tggtgttctt caacacgatg cgccgcacct tctcgcacgt ggggatctac
    40261 ctcggcgacg gcaagttcgt gcacgcgccg tcgagcggcg gcaaggtccg cgtcgagaac
    40321 atctccacgg cctactgggc caagcgcttc aacggcgcgc gccgactgct ggacgaagag
    40381 cccctcggcc tgagcgcaca ggtgatgggc gcgcgctgaa acccgcccta ccgacgaaaa
    40441 cgcagaggcc cggcgcgacc gggcctctgt gctttctgcc ttgcgcgtcg cgctcagcgg
    40501 cgccggctgc gcgccttctc acagcgctgt ggacaatcct cgcagcgcgc ccccatctgg
    40561 cgatcgagcg cctgctgcag cgcgcaggtc gagcgccggc agcacaccac ctgcacgccc
    40621 tgcttgcccg cggcctcgcg aaagcgctgc atgacgttgt gcccgaggaa atcggtgaac
    40681 aggatcacca cgccgatccc gctcggcaag ggggcgctgc ggcgctggtg cgtcgtgtcg
    40741 cggccgctga catgggcggc gatgcggatg ccgaagttgt gcaacacatc cgggatgttg
    40801 ccgaggcggt cggcaccgac gagcaacgca ttcatggaaa ctccttgttg agaattcttc
    40861 tcaaccatga tgcagtgaat gcgagctatt tgcaactgcg aacctttatc gttagtatcg
    40921 ctgcaccgcc aacactccag ggttcgcaaa ccatgagcaa gaaagtcctc ctcgcctcgc
    40981 tgatcgccgc cttcggcctc tccggcgccg ctaccgctgc cgagctgaac gtctactccg
    41041 cccgccacta ccagacggac gaagagctct acggcaactt caccaagcag accgggatca
    41101 agatcaaccg catcgaggcg aaggaagacg agctgctcga gcgcatccgt aacgaaggtg
    41161 ccaacagccc tgccgacatc ttcgtgacgg tcgatgcgtc gcgcctcgcg aaggcggacg
    41221 agatgggcat cttcgagccg gtgaagtctg ccgagctcga ggcccgcatc ccttcccacc
    41281 tgcgtgcacc gaactggttc tcgtattcga cccgcgcgcg cgtgatcgtc tacaacccgg
    41341 acatggtgaa ggccgagcag gtgcagacct acgagcaact cgccgacccc gcgctcaagg
    41401 gccaggtgtg cacccgctcg ggcagccacc cctacaacct ctcgctcggc gccgcgatga
    41461 tcaagcacaa cggcacggaa gcgaccgaga actgggccaa gggcatcgtc gccaacttcg
    41521 cgcgcgcccc caagggcggc gacaccgacc agatccgcgc cgtggccgcg ggtgagtgcg
    41581 gcgtggcgat cgccaacagc tattacctcg cgcgcctgat gaactcggac aagcgcgagg
    41641 atcaggccgt ggtcgcgaag atcaaggcgg tgtggccgaa ccaggcgagc tggggcaccc
    41701 acatcaacgt gtcgggcgcc ggcatgctca agcacgcgcc gaacaaggag gccgcggtca
    41761 agttcctcga gtatctcgcc tcggaccagg cacaggaata cttcgccaat ggcaacaacg
    41821 aatggccggc ggtgccgagc gtgaagctgg acaaccccgc gctgaagaag ctgggcgagt
    41881 tcaaggccga caccctgccg atcggcgagc tcgccgacac ggtggccgaa gcccagcgta
    41941 tcttcgaccg cgccggctac cgctgatccg tactccccgc gaccgacgct gccgcgccag
    42001 cgtcggtcgc ggcggcctgc ctgccgcctt actcaatccg ggcgtttccg cccgcaacat
    42061 cctcgccagc ttctccagca atcacggggg ccagcacgac gcggttgcgt ccggcgtgct
    42121 tcgctgcata gagagcctcg tccgcacggg cataggcgcc ctcgtagccc tcgtcgcgcg
    42181 catccagcat ggtcgcgccg atgctcaccg agtagtgcag cggccccgac tcgatgctcg
    42241 cgggcgagtc cgcaaccacc ctgcgcagcc ggtccgccac ccgcaccgcg ccgagcgcgt
    42301 cgatgcaggg cagcaggatc gcgaactcct ccccacccag acgcgcgaac acgtcggcct
    42361 cacgcagctg cgcactgacg gttgcggtga agtggcgcag cacctcgtct cccgcggcgt
    42421 ggccgtgggt atcgttgatg cgcttgaaga agtcgagatc catcagcaat agcgccgccg
    42481 gcgcctggtt gcggcgcacg cggcccagct cgccgcgtac cacctccatg aaatggcggc
    42541 gattccacag gccggtgagc gggtcgctgg tggcgagctg cagcaggctc tcctccatgg
    42601 ccttgcgctg ggagatgtcc tggtgaatgc cgaccatgcg caaggcctcg ccgccctcgc
    42661 cgcgatcgag cacgcggccg gcggcgagca cccagatcca gtgcccgctc ttgtgcttca
    42721 ggcggtactc cgcgcggtag gcgtcgcgga ccccgcgcag gtgcggctcg agcgagtcgc
    42781 ggatgtcgta ccagtcgtcc ggatgcacca gggactccca ggtcgacaca ttcccggcca
    42841 gctcgtcggg ggtgtagccg agcatcctgc accacaccgg gctgaagttc gcgcgcccgc
    42901 tcggtacgtc ccagtcccac aggccgagct cggcaccttc gagggcgagc atcaggcggc
    42961 gttcgcgctc ggcgatctgc tcgcgcaccc ggcgccgctc ggtgaagtcg cggctcacac
    43021 ggatctcgcc gagctgcctg ccgtcggcat cgaaatacgg tgtgcgcagc gtgtcgagca
    43081 ggcgcagcgt cccgtcggcc gcctccagcc actcctcgtg gttctcggcc ccgctcacgg
    43141 cctcctgccc ggcctcggcg agcggcaggc ggcctgcgaa cacctcgccg tcgctgcgcc
    43201 cgatcagtgc gtcctcgcga atgccgtagg cctcggcgaa ggccttgttg cagcccaggt
    43261 aacgcccgtc gcggtcgcgg aacgcgatca ggtctgggac cgagtcgatc agcccgcgca
    43321 gcagcgcacg ctcggccgcg agcgcgcgct gcggcgcgcg cacgccggac acgaacaccg
    43381 cgcggtagat catggtgaac gccgccgcct tgtaggcatg cccgagcgcg ttgtagaggt
    43441 cggcgaccgc ggcgtagcgg gcgaaatgca actccgccag cgccatcgtc acggcggcgg
    43501 cggccagcca gccgccgacg gattcgccgt cggccagcgc acggcgcgcg agcagcacgg
    43561 cagcgccgag gtagagcagc gcgagcccgc attccagcgc gctcttgagc ggcgtgaccc
    43621 cgcgcccttc gacgaaggtc gcggggaaca cctgcgggtg ggcgaggacg agccagctcc
    43681 agcccagcgt gacgacgatc gcgccgagca cggcccaggc ggcggcaggc ccaccgccct
    43741 cgcgctccgg cagcaccgcg tgggccagca agccgagcgc tccgatcagg cgggccatca
    43801 accagaaacc gatcgccttc tccgcctgat tgggcgtgaa gaagggcggc atgcccggat
    43861 acgacatcag gtgggcgaaa tcgagcaggc cggcggcaag acacgccgcg ccgagccaga
    43921 ccagcctgcc accgcgcgcg ctgcggcgca ggttccagcc gagcgcgaac accatcccgg
    43981 caaccacgat cgcgaagatc tccagccccg catgcagcgg cagatagtcc agcgcatcgg
    44041 cgaatacgtt caccggaggc aggaatatgc tgaatacgaa gaacacgccg agcaggaccg
    44101 tggccagcag cgggtgacgg aaacggcgca gcaccgaggc cgacacgctc agcacgcctc
    44161 tcgccgaggg acctcggcag gcctgtgccc gccgccgcaa ggcagagcgc ggaccacgcc
    44221 caggcgggac ggagtgcggc atgcggcggt gcggacgggg aactcggaca tcacgtaatt
    44281 atgcatgatc ggcgcccggc gaccgccccg gcggcgcacc ccgcgtgcac taattcgcgc
    44341 ccgcaggcac gcggatcagc cctcacggcg gcgcacgcgc aggatctggc gggaaatcca
    44401 gaacatcggc agcaggccca ccgccacgat gatcagcgct gcggtcgagg cctccgccag
    44461 gcgctcgtcg gcggcgagcg tgtgtgcctg ggtggccagg gtgtcgaagt tgaaggggcg
    44521 gatcaccagc gttgccggca actccttcat gacgtcgacg aacaccagca ggccagcggt
    44581 gagcagactg ccgcgcagca tcggcatgtg cacccggcgc agggtcgccc acttgccgaa
    44641 gcccaggctg cgcgaggcgt cgtccatgtt cggggtgatc ttgcccaggc tggactcgac
    44701 ggtctgcaag gccacggcga gaaagcgcgc gaggtaggcg tagaccagcg ccgcgatgcc
    44761 gccggtgagc agcaggcccg ggttgaatcc ccacatcgcc tcccagccct cggccagcca
    44821 tctgtcgagg cgggtgagcg ggatcagcac gcccaccgcg atcaccgagc cgggcaccgc
    44881 atagcccagg ccgacgatgc ggttgagcgc ctgcggcagg cgcgagcgcg ccaggcgcgc
    44941 ggcgtaggcg agcagcaccg cgagcagcac cgcgaccacc gcggtgatcg cggcgagcac
    45001 gaagctgttg tgcgccagtt cgacgaaacg cgcgccgaac tgggcgtcgc cctcgaggaa
    45061 ggccatgcgc agcagcagcc ccgccggcag caggaagccg agcagcagcg gcatgaagca
    45121 ggcgaaggcg gcgagcaggc cgagcggcag cggcaggcgc agccgcaccg gcatcgccac
    45181 ctggcgcgag gtgttgttga agcgcgcgcg tccgcgcgac atgcgctcca gggtcaagac
    45241 caggatcacg aaggcgagca gcgcagccga cagctgcgcc gcggcgatgc ggtcaccgag
    45301 cgagaaccag gcgcgataga tgccggtcgt gaaggtctgc acgccaaaat aggacaccgt
    45361 gccgaagtcg gccagcgtct ccatcagcgc cagcgcggtg ccggccacca ccgccgggcg
    45421 cgccagcggc agcgagacgc ggaagaacga gccccacggc cccagcccga gcgtgcgccc
    45481 ggcctcgagc atgccgcccg cgcgctccag gaaggcggtg cgcgcgatca tgtacacata
    45541 cggatagagc acgaacatga acatcgccac cgcgccgccg accgtgcgca cgtccgggaa
    45601 ccagtagtcg ccgcgccgcc actcgaaggt ctcgcgcagc cagccctgca ccggacccac
    45661 gaactggagg aaatcggtat acacataggc catcacgtag gccggcatcg ccagcggcag
    45721 caccagcgcc cactccagga agcgccgtcc cggaaaatcc agcatggtgg tcagccaggc
    45781 cgaggtcacg ccgatcgacg acaccccgag acccacgccg atgcaaagca ccacggtgtt
    45841 gaacacgaac tcgccgagca ccgtgtcggc caggtgcgac caggtcgcgc cggtgtcgcc
    45901 ggcgagcacg ttggagaaca ccgacaacac cggcgccgcg atcagtgcgg ccacgacgac
    45961 cgccgccacc gacagcgaag aaaaccgatt gcgcatcgcg ccctgccctg ccttcgaacc
    46021 catgccgttc ccatgattgc gccccggcgc cggaaatcgg cccccactga cgcagcgaat
    46081 tataattgat cgcatttgga acaccggggt gcaataattc cccacgccca caggccctcg
    46141 acgaccgcga tgtcccacct cgacctttcc cgcatcgacc tcgccttcgg cagccacctc
    46201 gtggtccgcc agctctccct gcagctcgag aagggtcgca tcggctgcct gctcggcccc
    46261 tcgggctgcg gcaagaccac cgtgctgcgc tgcatcgccg gcttcgaacg cctggcggga
    46321 ggcgagatcc gcctcgacgg cgaggtcgtc agcacgccgc gccacatgct gccgcccgag
    46381 cgccggcgca tcggcatggt gttccaggac tatgcgctct tcccgcacct ctcggtggcg
    46441 gacaacatcg gcttcggcct ccggcgcgac agcgccgccg tgcgcgctgc gcgggtggac
    46501 gagctgctcg cgctggtcgg cctcgcgggc cagggccaca agtacccgca cgagatgtcg
    46561 ggcggccagc agcagcgcgt cgcgctcgcg cgcgcgctcg cgcccaagcc cagcctgctg
    46621 ctgctcgacg agcccttctc caacctcgac gtcgaattgc gcgaacgcct gtcgtacgag
    46681 gtgcgcgaga tcatcaaggc caccgacacc accgcgatcc tggtgaccca cgaccagcac
    46741 gaggccttcg cggtcgccga cgagatcggc atcatgcacg agggccgcat ccagcagtgg
    46801 gacacgccct acaacctcta ccaccgcccg gccaaccgct tcgtcgccga cttcatcggc
    46861 cagggcgcct tcctgcgcgg caaggtgctc gacgaccacc gcgtgcagat cgagctcggc
    46921 gtgctcgaca gcgcccaacc gctcgtgtgc tgtgccgact gcgccggctg cgtgcacggc
    46981 agcccggtcg acgtgctgct gcgccccgac gacctcgtgc acgacgacac cagcccgctg
    47041 cgcgcggagg tggtgcacaa ggccttccgc ggcgccgaca tcctgtacac gctgcgcctg
    47101 gcgggcggcg cgcgcgtgct ctcgctggtg cccagccacc acaaccacgc catcggcgag
    47161 cgcatcggca tccgcctcga tgtcgaccac gtcgtcacct tctccgacgn nnnnnnnnnn
    47221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    47281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnng caccacgcgc gggcgggccg ggcacctgga
    47341 tcaccccggc gatgcgcgcc gcctacctgc acatgcacga actgggctgg gcgcacagtg
    47401 tcgaatgctg gcgagacggg cgactggtcg gcgggctcta cggcatggcg atcggtcgcg
    47461 tcttcttcgg cgagtcgatg ttcgcgcgcg agaccgacgc ctccaaggtc gcgctcgccc
    47521 acctcgcgcg gctgctcgcc gagcgcggct atggcatgat cgattgccag atgaccaccg
    47581 cccacctgct ctcgctcggc gcgcgcgagg taccgcgggc gcgcttcgcc gccgccttgc
    47641 gccagtgggc gcatgacggg ccttcgccgc agcgctgggc ggaagatgcg atgcgggatt
    47701 tcgactgggc ttgaaacggg aaggcgagtt gcaggacgga cgcgatgaaa tcggactacc
    47761 cctacgccct catccagttc tacgccacgg cgccctacgc ctgctcctat ctggccgggc
    47821 gcagcgcgcg ctcccaggtc gccacccccg gccacctgat cgatccacag gtctatagcg
    47881 agctggtgcg acgcggcttt cgccgcagcg gggtgttcac ctatcgtccc tactgcgacc
    47941 actgccaggc ctgcgtgccg gttcgcatcc cggtcgagcg cttcgagccc gaccgcagcc
    48001 agcgcagggc gtgggcgcgg catgccgacc tcgtgccgat cgaacgcccg ctcgacttcg
    48061 tcgaggagca ctaccagctc taccagcgct accagaccgc ccgccacgcc ggcggcggca
    48121 tggacctcga caaccgtgag cagtacgcgc acttcctgct gcagagccat gtcgacaccc
    48181 gcctggtgga gttccgcagc cacggcagcc tgcgcatggt gtgcgtgatc gaccgcctca
    48241 ccgacgggct gtcgagtgtc tacaccttct acgatcccga ccagccgcgc agcgccctcg
    48301 gcacctgggg cgtgctctgg caggtggagg cctgtcgggt gctcggactg ccgcacgttt
    48361 atctcggtta ctggatcgga gagagcccga agatggccta caaggcgcgc ttccgcccgc
    48421 tcgaggcgct gatcgacggc gactggcagc cctttccggg cgaattcgcc tgatccgggt
    48481 gcccggcagc caagtcgact cgctacaatc gcgcgatgct ctacgaactc gcccgccccc
    48541 tcctgttcgc gctcgacccc gagaccgccc acaacctgac cctgcacggc ctgcactacg
    48601 ccggcaagct gctgcccgcc gccgcgcccg aaccggcagg cgcggtcgag gtcatgggcc
    48661 tgcgctttcc caaccgcatc ggtctcgccg ccgggctcga caagaatggc gaggcgatcg
    48721 acggcctcgc ccgcctcggc ttcggcttcc tcgagatcgg cacgatcacg ccccgcccgc
    48781 agccgggcaa cccgcgtccg cgcatgttcc gcctgcccga ggtgcacggc atcatcaatc
    48841 gcatgggctt caacaaccac ggcgtggagg tcctgctcgc gcacgtgcgc gcggcgaaat
    48901 accgcggcat cctcggcatc aacatcggca agaacttcga caccccgatc gagcgcgccg
    48961 ccgacgacta cctcgcctgc ctcgacgcgg tgtatgcgct ggcgagctac gtcacggtga
    49021 acatctcctc gcccaacacc aagaacctgc gccagctgca gggcgaatcc gaactcgacg
    49081 acctcctcgg ccgcctcaag gcggcacaga cccgcctcgc cgagcaacat gggcgctacg
    49141 tcccgcttac cctcaagatc gcccccgacc tcgacgacgc acaggtgagc aacatcgccg
    49201 acgcgctgcg tcgccaccgc atcgacggcg tgatcgccac caacaccacg atcgcgcgcg
    49261 acaaggtgca gggcctcgcc catggcaacg agcagggcgg cctgtcaggc gcgccggtgt
    49321 tcgaggcctc caccgcggtg gtgcgcaagc tcgcggcggc gctcgccggc gaactgccga
    49381 tcatcgccgc cggcggcgtg ctcgagggcg cacaggcgcg cgccaagctc gaggccggcg
    49441 ctgcgctggt gcagctctac agcggactca tctaccgtgg cccggcgctg gtgcgcgagt
    49501 gcgtgcgcgc caccgccggc tgatttcctt cccgacttcc ttcacgtccc gccgcagcgt
    49561 gcgcgggtcc tggcgaaaac gccttcgccg gcacgcatgc cgacctaccg cccctccgag
    49621 gagcccacga tgacgcatcg ccgcaagttc atgctctccg ccgccgcgct cgcggtcgcc
    49681 gccaccctgc ccttcgccgc gcaggccgcc gatgccgcga agatcggctt cgtctatgtc
    49741 agcccgatcg gcgacgcggg ctggacctac cagcacgaag agggccgcaa ggagctcgag
    49801 aaggcgctcg gaggcaggat cgagacgcgc tacgtcgaga acgtcgccga aggcgccgac
    49861 gccgagcgcg tgatccgcga gttcgccgcc agcggcagca ggatcgtgtt cgccaccagc
    49921 ttcggctaca tgaactacgt ggagcgcgtc gcccgccagt tccccgacgt caccttcctg
    49981 cacgccaccg gctacaagtc ggcgaagaac ttcgcgccgt acaacgcgcg cttctacgag
    50041 ggccgctacc tcaacggcgt gatcgccggc aagatgacca agtcgaacgt gctcggctac
    50101 gtcggcgcct tcccgatccc cgaggtgctg cagggcatca acgcgttcac cctgggggcg
    50161 cgcagcgtga acccgaacgt cgaggtgcgg gtgatctggg ccaacagctg gtacgacccg
    50221 ggcaaggagc gcgaggcggc gatgaccctg atctcgcagg gcgccgacat gctcacccac
    50281 cacaccgact ccaccgccac cgtccaggcc gcggaagaaa agggcgtgta cgccttcggc
    50341 taccactccg acatgtcgaa gtacgccccc aagtcccagc tcaccgccac cacccaccac
    50401 tggggcgagt tctaccgccg caccgtcaac gcggtgctcg acggcacgtg gaagcccgag
    50461 ggcgtgtggg gcggcatgaa ggacggcatg atccgcctcg cgccgctcaa cccggccatc
    50521 cccgcggacg tgcaggccat ggtcaaggaa ctccagggcc gcatcaccgc tgggagcttc
    50581 caccccttca ccgggccggt gctcgaccag gccggcaagg accgcctcgc cgccggagcg
    50641 gtgatggacg acgccaccct gggcaagatg gactacttcg tgcagggcgt gagctcgcgc
    50701 ctgcccaccg cgaggtaagc ggttttccgc tgccgcgcgg cccggcgagg agccccctgt
    50761 gcagcggcgc tcgccgccgc agccctgctt cagggcccgg gcggctcggc gcgatccgga
    50821 cggtccgccc ccgcctcgtc gtccgccggc aagccgttgc gcaggcaggc cgagaggccg
    50881 gtggcgatcg cgtcggccat gcgcgcctgg cgcacgggat cgcgcagcag cagctcctcg
    50941 tcgcggttct tgagcacacc ggcctcgaac agcaccgccg gcatgcgcgc gtggcgcagc
    51001 accgccagcc cgtcgtagta gtgcaccgcg tgctcgcggt cggcgtagct gcgccggcgg
    51061 ccgttcttgt gcgtaggctc gaagcccatg cgctgcaggc gggcgccgat cgcacgcgca
    51121 cacaggatgc tcatcgcggt gtccgggttg tcgcgcgaca cgaagagcga gtgcccggcg
    51181 aattcatcgt tgtagtcgcg cgcgcgcccc tcccaggtcc atggccgcag ttcgaaggcg
    51241 ttgaccgagt cgtggtgcag cgagagcagg aaggccgctc cggcctcgcc ggcggcctgc
    51301 ggccgcgcgc gcaggctcgc gatgcggccg tcggcgttga ggatgctcac cgcccagccg
    51361 cgcgcgtgca gtgcatcgac cacatgcacg gaaagatcgc ggttgaactc gaactcgctg
    51421 cggccgcgcg cgctcgtcgc cccgggcgcc tgcagggtgt ggccgacgtc gacagcgatt
    51481 ggcccggacc cctcgccgcc agccagcgcc ccccccgcga tcgccgccag cacgagcgcg
    51541 agcagcccgc ggcgcggcgc acgctgccac gcacccctgc tccgtgcatg ccccgaggcc
    51601 tgcaaaaacc cgcaaagcga gcgcccatgc ggatggaaaa gttccactcg ggctacatct
    51661 tgattcaaat catggagagc gcgggtgccc gccgtgacaa tccgcccacc atcggcattg
    51721 ccgtggacag ttgtacccct gacccacgcg ggcgaaccga gaccttcctg acaaaacgag
    51781 acaagcgatg aggagtactc catgagcggt attttcacaa aatcgatggc gcggaacatc
    51841 ttctacgggg ggacgacgtt cttcttcctg ttgttcctgg cgctcacctt cgacaccgag
    51901 cgcgagctgc ccaaccggga caaccgcgcc gccatcaccc ccgaggttgc cgccggcaag
    51961 cacatctggg aaacccgcaa ctgtctgggc tgccacacgc tgctcggcga gggcgcctac
    52021 ttcgctcccg aactcggcaa cgtctacaag cgccgcggcg gcgacttcat caagggctgg
    52081 atgcaggcca tgcccaccgg agcccccggc cgtcgccaga tgccgcagtt caacctcacc
    52141 gatgaagagc tcgaccagct ggtggccttc ctgaagtaca cctcggaaat caacaccgcc
    52201 aactggccgc ccaacatcga gggctgatcg gaactctgga gaccacaagg ggatatccat
    52261 gcaatacaaa tcacaagcgg tcgccatgcc ctacttcatc gcggcgatcg gtctgttcgt
    52321 ggggcaaatc atcttcggcc tgattctggg cctgcagtac gtcgtcgggg acttcctgtt
    52381 cccggagatc ccgttcaacg tcgcgcggat ggtgcacacc aacctgctga tcgtgtggct
    52441 gctgttcggc ttcatgggtg cggcctacta cctgatcccg gaagagaccg agaccgaact
    52501 cttcagcccg aagctggcgc tggcgatgtt ctggatcttc ctggtggccg gtgcgctgac
    52561 catcgtgggc tacctgctcg tgccgtacag cacgctggcg tccatgaccg gcaacgacat
    52621 cctcgccacc atgggccggg agttcctcga gcagccgctg ttgaccaagg tcggtatcgt
    52681 gatcgtcgcg ctcgccttcc tgttcaacat cacgatgacc gtgctcaagg gccgcaagac
    52741 cgtcatcagc atcgtgctgc tgctcggcct gtggggtctg gccatcttct tcctgttctc
    52801 cttctacaac ccggtcaacc tcgtccgcga caagttctac tggtggtggg tggttcacct
    52861 ctgggtggaa ggcgtgtggg agctgatcat ggccgcgatg ctcgccttcg tgctcatcaa
    52921 ggtcaccggc gtcgaccgtg aagtgatcga gaagtggctg tacgtcatca tcaccctggc
    52981 gctcgtgacc ggcatcatcg gtaccggcca ccactacttc tggatcggta cgccggaata
    53041 ctggcagtgg tggggttcga tcttctccgc gctggagccg atccccttct tcgccatgac
    53101 cgtcttcgcg ttcaacatgg tcaaccgtcg tcgccgcgag catccgaaca aggctgccgt
    53161 gctgtgggcg ctcggtaccg gcgtgatggc cttcctcggc gctggcgtgt ggggtttcct
    53221 gcacaccctg gctccggtga actacttcac ccacggctcg cagatcaccg ccgcacacgg
    53281 tcacatggcg ttctacggcg cctacgtgat ggtcgtgatc accatgatca gctatgccat
    53341 gccgatcctg cgtggccgcg ccgccaaccc gaccaaggcg caagtgctgg agatgtgggc
    53401 gttctggctg atgaccatcg cgatggtctt catcaccctg ttcctgaccg ccgccggcat
    53461 cctgcaggtc tggctgcagc gcgtgtccga caccccgatg tccttcatgg ccacccagga
    53521 tcagctgatg ctgttctact ggatgcgcga gtgggtgggc gtgatgttct tcatcggcct
    53581 gctggcctat ctcgccagct tcttcgtgaa gggcgatgcc aagggggtcg tgcacggctg
    53641 agccctgccg accgacaagc ggtaaaaagc ctggatcatc cagggtaagg ggttggggcg
    53701 gcgcgagccg cccctctttt tttgcgtgcc acgctcgcag catggagcgg ccgctagaat
    53761 atcgggcttc gtccgcgccc gaacggcact ccgccaccac cggatccccc cggcgcgcgc
    53821 gtcccatcgc ctccgctcgc tcccctccgc ccgtgcccaa cgcctccctt ccaccctccc
    53881 cgccgtccca cgacgcatct cccgtcctgc acacgagcgg tgccgaacac cccttccgca
    53941 tcgcgatcaa cggctacggc cgcatcggtc gttgctacct gcgtgccctg cacgaagccg
    54001 gcctcgccgg gcgctaccgc atcgtcgcga tcaacgagcc tgcggacctc gccagcatca
    54061 cctacctcac ccgcttcgac tccacccatg gcaggtttcc gggggtggtg gaccgcagcg
    54121 agcgcgagct gatcgtggac ggtcatgcaa tccacgtcag ccacgcgagc accccggaag
    54181 aggtcgactg ggccgcattg gggctcgatc tcgtcgtcga atgctccgga cagtacggcg
    54241 gacgccgcga cttgcagcgc ttcatcgctg ccggctgccc gcgactccta ctgtcgcacc
    54301 cgggcaacgg cgccgaggat gtggatgcca cggtggtgtt cggcatcaac gaagacgcgc
    54361 tgcgcggccc cgagcgcctg gtgtcgaacg cgtcgtgcac caccaacgcg gtggtcccgg
    54421 tgctcgactg cctgcaccgc gagatcggca tcgagcaggc cctgctcacc acgctgcatt
    54481 cggcgatgaa cgaccagccc ctgatcgacg gctaccacca cgccgacctg cgccgcacgc
    54541 gctcggcgat gcagtcgatc atcccggtgt cgaccggcct ggcgcgcggc gtcgaacgcc
    54601 tgctcccggc gctggccggc cgcgtgcagg cgaaggcgat ccgcgtgccc acccacaacg
    54661 tctccgcgat cgacatggtg ctgagcttcg gccgcgaggt ctcggccgag gccgtcaacc
    54721 gcctgctgcg cgagaccgcc gccgggcccc agcgcggcct gctcgcgtgc tccgacgagg
    54781 cgcacgcctc gatcgacttc aaccacgacc cgcactcggc gatcatcgat tgcagccaga
    54841 cgcgcgcagt cggaccgcgc atgctcaatc tggtggtgtg gttcgacaac gagtggggct
    54901 tcgccaaccg catggtcgac gtcacctgcc gctggctcgc cgcgacaggc tgaacacgaa
    54961 cgaatcccaa ttaaccacga tcaagttaaa gccgcgccct tctgcctaga ctgcgccgca
    55021 tggataccgt caccactccg ccgagttcca tgccggccgg cggaccggca cagactcacg
    55081 caccccgcct cgcgggcgac ctcgcgatct ggttcttcat cctcgccgag ttgctcgcct
    55141 tcggggtctt cttcgccgcc tatgcctttg cgcgcgccaa gaacatcgag ctcttcgctg
    55201 ccgagcaggc cgcgctcaac cgcaacgcgg gcgcgctcaa caccgtgctg ctgctcaccg
    55261 cgagctactt cgtggtgcgt gccgtgcagg ccgccgaggc ccaggcctcg cgccagtgcg
    55321 ccaactggct gggcggggcg atcctcaccg gtttcggctt catcgtcgtc aagctgagcg
    55381 aatacgccgc cgccttcgag cacaacatca gcctgtcgag cagcaccttc cacatgttct
    55441 acctgtcgct gaccttcttc cacttcatgc acgtgatcct gggcctggtg atcctgatcg
    55501 cgatgtggaa cggcgcgcgc cagggccgct accgcccggg cgagatgaac ggactggaga
    55561 ccggcgccgc ctactggcac atggtcgacc tggtctggct gatcctcttc ccgctcgtct
    55621 acgtcatcca ctgaggagcc cgccatgagc gcacgcatgc acggaacgcc caggggctcc
    55681 acgatcctgt tcgccaccct gatcctcgcc accttcgcca cctggggcat gggctcgctc
    55741 ggtgtcaccg gcacctgggg cgtcgccatc ctcgccgcga tctcgttctg gaagggcgcg
    55801 gtggtcatcc tcgacttcat ggcgctgcgc catgcaccgc tgctctggcg cgcgatcacg
    55861 atgggctgga tcatcgtcgt ctgggccctc atcgccatcg cctacatcaa gggactcgct
    55921 caatgaagcc cgatacgccc aacctcgaca ttcccttcta ccagcccgcc ggcgacgagg
    55981 tggacatctt ccagcacgcc tggaagaacc gcctgcccct gctgatcaag ggccccaccg
    56041 gctgcggcaa gacgcgcttc gtctcgcaca tggccgcccg cctcggcctg ccgctgtaca
    56101 ccgtggcctg ccacgacgac ctcaccgcct ccgacctcgt cggtcgccac ctgatcggcg
    56161 acggcaagac catgtggtgc gacggaccgc tcacgcgcgc cgtacgcgag ggcggcatct
    56221 gctatctgga cgaggtggtg gaggcgcgca aggacaccac cgtggtgctg cacccgctcg
    56281 ccgacgaccg tcgcgtgctg ccgatcgacc gtaccggcga gctcctcgag gcgccaccct
    56341 ccttcatgct ggtggtgtcc tacaaccccg gctaccagaa cctgctcaag ggcatgaagc
    56401 cctcgacccg ccagcgcttc gtcagcctgc gcttcgactt cccgcgcccc gagcaggaag
    56461 aggcggtgct gatcggcgag accgcgtgcg cgcccgacct cgccaggcgc ctggtcgcca
    56521 tcgccaacgc gctgcgcgcg ctcaaggacc gcgacctcga agaggcggcg agcacccgcc
    56581 tgctcgtgta cactgcgctc ctcgtcaagg acggcatgga cccggtggcc gccagccggg
    56641 tcggcatcgt cgagagcctc accgacgacg ccgacgtcgc cgagggcctg atggaggtgg
    56701 tcgccgccac cttcgggcgc tgagccccgg gacaccgcga tggaaatcaa gcgcgccgat
    56761 ccgctccgcc acgtcatgcc cggcccgcgc ctggcggtcg tcgccgaggc gctgttcctg
    56821 atcaacctga tgctgctgcc cggcctcgcc ttcgccgcat tgatggtgct gtggtacctg
    56881 catcgcggcc atcccgaccc gctggtgcgc aaccacctgc gccagaccgg gtggacctgc
    56941 atctggggcg ggcttctgct ggtcgtgatc agcgtcgcga tcttcctgct cggcggcttc
    57001 gacaatccgt ggacctgggt gatcggcgtg ctctacttca ccttcgtcca ttccaccctg
    57061 atcctgctcg gcgtgatggg cctgtcgcgc gcgatcaacg ggcgcagctg gcgcttcccg
    57121 gtgttcgggc cgcgcgagtc ctcctgagcc ggccggtgcc cacgatgaac accgaagccc
    57181 ctgcgcgcaa accgcagcgc gtcatcccga tcgccaccgc ccctgcgggc gatgcggccg
    57241 ccgccgcggc gatgcagcgc cgacggcgtg ccttccaggc cggcttcttc gcgctcttcg
    57301 tgctcgcacc ggtgttcgac ctcttccgct acgacctcga cgccgaccac gcctggctgc
    57361 tcggaatgga atggcggctc ggcctcgacc ccttcctcgc cggccaggcg agcgcactcg
    57421 aggcggccgg gagcatcatc ctgaatctct tcgtgcccct gctcgcgctc gccgcgctgg
    57481 tgatcggcgc ggcgtggaag tggggacggc tgtactgcgg ctggctgtgc ccgcacttt
//
LOCUS       DAOTIN010000009        56308 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_557_length_56308_cov_8.601479, whole genome shotgun sequence.
ACCESSION   DAOTIN010000009 DAOTIN010000000
VERSION     DAOTIN010000009.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 56308)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 56308)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56308
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_557_length_56308_cov_8.601479"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1190
                     /locus_tag="P5537_02550"
     CDS             <1..1190
                     /locus_tag="P5537_02550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="cytochrome D1 domain-containing protein"
                     /protein_id="HRV76954.1"
                     /translation="LRDAGKLALVDGDTHKIWKILDTGYAVHISRLSASGRYVYTVGR
                     DGLTTIIDMYYEEPTTVATVRLGSDARSVDTSKFKGYEDKYLIGGTYWPPQYSIMDGE
                     TLEPMKIVSTRGNTVDGDYHPEPRVASIVASLTKPEWVVNVKETGMILLVDYSDISNL
                     KTTTIESAKFLHDGGWDASGRYFMVAANASNKVAAVDTKTGKLAALVDTAKIPHPGRG
                     ANFVHPEFGPVWSTGHLGDAVVSLISTASDDPKFAKYKANNWKVVQELKMPGAGNLFV
                     KTHPKSKNFWADAPMNPERELAEAVFVFDKADLKKEPIRLDVAKDSGLPESKAIRRAV
                     QPEYNEAGDEVWISLWGGKTDQSAIVIYDDKTLKVKKVITDPAIVTPTGKFNVYNTMH
                     DVY"
     gene            1259..1870
                     /locus_tag="P5537_02555"
     CDS             1259..1870
                     /locus_tag="P5537_02555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NapC/NirT family cytochrome c"
                     /protein_id="HRV76955.1"
                     /translation="MSEQNSDNSKQENSGGLWARLRRPSGKSLGGLLAVGFVVGVLFW
                     GGFNTALEATNTEKFCISCHEMYDNVYMEYKETIHYNNRTGVRATCPDCHVPKDWTHK
                     MIRKVQASKELWGKMVGTIDTREKFEAKRLELARNEWKRMKASDSRECRNCHSFESMN
                     KDSQKQRARKQHEMALEDNMTCIDCHKGIAHHKPEGMTEEDEE"
     gene            1913..2791
                     /locus_tag="P5537_02560"
     CDS             1913..2791
                     /locus_tag="P5537_02560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ethylbenzene dehydrogenase-related protein"
                     /protein_id="HRV76956.1"
                     /translation="MTMKKTMIAGAVGALLALGTGSALAAAPDWSKVEGKDITAFYPG
                     VSPMEWIQKGTEHGGARALKKGETCADCHSDEAADMGKKMASGQKIEPTPIAGKAAFI
                     PVKVQAAHDGENLYVRFSWKQPAASGAAKMDDKNPVKIAFMLESGGKVELADQSGCWA
                     TCHTDSRTMPGADEAKTKYVKGGSLAEGKFYDLYQWRSGENKGYNGYVADKRVMEGGN
                     ALVSAEGKKDGDSWSVVFTRKLAAGDGDVKLESGKAYNFGFAIHDDNAAGRFHHVSLG
                     YKLGLDTDGHIKAAKQ"
     gene            2931..3260
                     /locus_tag="P5537_02565"
     CDS             2931..3260
                     /locus_tag="P5537_02565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="plastocyanin/azurin family copper-binding
                     protein"
                     /protein_id="HRV76957.1"
                     /translation="MNARFAPACLLAAAFSFAGGSPALAAEHQVIVEKYAFAPMELRI
                     KRGDTVTWVNNEKRVSHSVLMIGRSEESERFFPGEKWSRAFPEAGRFEYRCGPHPEML
                     GVVIVED"
     gene            3464..3847
                     /locus_tag="P5537_02570"
     CDS             3464..3847
                     /locus_tag="P5537_02570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c"
                     /protein_id="HRV76958.1"
                     /translation="MKIPPLLAHAVVLLGAALVSAYAAASERAPVEPDPARARELIHI
                     VRQDCGSCHGLTFKGGLGPALTAEALADKPAEGLVATIVGGRPGTPMPPFQTILSEAE
                     AEWIVYWLMRGFPADAGLPQAAARN"
     gene            3938..5146
                     /locus_tag="P5537_02575"
     CDS             3938..5146
                     /locus_tag="P5537_02575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome D1 domain-containing protein"
                     /protein_id="HRV76959.1"
                     /translation="MSSREVRLAPPALWGVVLSAMVVLLSACSSTPPAALRGTGDLGV
                     VIERADGKVKVIETTGRSVLATVAGLGDLSHASVVFSRDGRYAFVFGRDGGLTKVDLL
                     ERRIVGRKVQAGNAIGGSISHDGSLVVVQNYEPGGIKAFDADTLELVADVPATTEDGT
                     RSKVVGLADLSGKRFIYSLFEAGEIRITDFSDPRKPVTQRFAGGKQPYDALVTPNGRY
                     YIAGLFGEDGLALIDLWNLDKGSRKILSGYGRGEQPLPVFKMPHLRGWSVAGNRAYLP
                     AIGRHEVLVVDTDTWQEVDRIKVKSQPVFAMARPDGREIWVNFAFPDNGWVQVIDTVS
                     GKVTDTLQPGRGILHMEFLSKGHEIWLSARDDNKVVIYDTASKQQIGGFDSASPSGIF
                     FTTRAARTGF"
     gene            5146..6195
                     /locus_tag="P5537_02580"
     CDS             5146..6195
                     /locus_tag="P5537_02580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HRV76960.1"
                     /translation="MPRQAILPEALDATGFRLLNEWQRDFPLEPRPFARIAQAVGAAE
                     EDVIAAYRDLAAQGLVSRVGAVFAPRRLGASALAALAAPPERLEEVAARVTREPAINH
                     NYQREHRYNLWFVVTAASRAQLDEVVAGIERDTGCAVIVLPLEEEFHIDLGFDLKAGG
                     AGRRSHAGPRAGEPIALGNADGGCELPAVERQLIGALQGGLALEARPFATLAARVGLT
                     EDAVISCIARWVDEGLIRRFGVVVRHHELGLEANAMCVWDVPDAEVSALGRRLAQEAA
                     VTLCYRRSRVLPDWPYNLFCMIHGSAREEVLAARDDLAVRLGLDRHPHAVLFSCRRFK
                     QTGARYLGAKDLAHV"
     gene            6188..6691
                     /locus_tag="P5537_02585"
     CDS             6188..6691
                     /locus_tag="P5537_02585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AsnC family transcriptional regulator"
                     /protein_id="HRV76961.1"
                     /translation="MSEAHSAAVAGRRGVAAKRPPDEVERRLINAIQGEFPLSERPFA
                     EVGAALGLSEDEVIARLQSLLDDRVLTRFGPMYQIERMGGAFCLAAIAVPEAQWASAV
                     EAVNAFPEVAHNYRREHALNMWFVLATETPEGIADCARRIEAATGLVVHLFPKEREYF
                     VEMRLVA"
     gene            6703..7260
                     /locus_tag="P5537_02590"
     CDS             6703..7260
                     /locus_tag="P5537_02590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HRV76962.1"
                     /translation="MPDNAALVRADARDEAARSADEAARVELDRRIVLATQGGLPLVA
                     RPYAAVAETLGVAEGLVRERLAAMLADGRIRRIGAVPNHYAIGYTANGMSVWDIDAAV
                     IDAVGERVGGLDFVTHCYRRPRHLPDWPYNLFAMVHAASREAALARVEEIAALITAEF
                     PGACRGCDVLFSSGILKKTGLRIGG"
     gene            7388..8596
                     /gene="nirJ"
                     /locus_tag="P5537_02595"
     CDS             7388..8596
                     /gene="nirJ"
                     /locus_tag="P5537_02595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006783 - heme biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0046500 - S-adenosylmethionine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heme d1 biosynthesis radical SAM protein NirJ"
                     /protein_id="HRV76963.1"
                     /translation="MFRISQFIRELDHPTPAGPRRNPPGPVVIWNLIRRCNLTCEHCY
                     SISADKDFPGELNTEEVFKVMDDLKAARVPVLILSGGEPLLRPDIFDIARRAKGMGFY
                     VGLSSNGTLIDESNIDAIDGIGFDYVGVSLDGIGATHDHFRRKEGAFEASMHGIRLCR
                     ERGIKVGVRYTMTEGNAHDLPALLKLVEDEHIDKFYFSHLNYAGRGNKNRAGDAHHRT
                     TREAMELLFETCLDLHRRGIEKDFVTGNNDADGPFLLHWVQRRFPDKAAHIEAKLRQW
                     GGNASGVNVSNIDNLGIVHPDTMWWHVPLGNVRQRAFGEIWNDLSNPLLAGLKQHPRK
                     LEGRCGACKYLDICNGSSRVRAEQVTGNPWAEDPACYLLDEEIGVTPADYGAERVVTT
                     PWTRIDKVSA"
     gene            8593..10248
                     /locus_tag="P5537_02600"
     CDS             8593..10248
                     /locus_tag="P5537_02600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome D1 domain-containing protein"
                     /protein_id="HRV76964.1"
                     /translation="MKRHATTLSSVLALAGALSAALVALPASASAEKAAAGAASAAAV
                     SPAAIDVPALYAQHCAACHAPNRLGAMGPALLPDNLGRLRKSEAAKVIAEGRAATQMA
                     GFAAQMSKEEIAALTEWIYSPVVPAPRWTDDDIRASRIVHVDPATLSDKPVFDADPMN
                     LFLVVEAGDHHVSVLDGDKLEPIFRFQSRFALHGGPKFAAEGRYVFFASRDGWITKFD
                     LWNLKVVAEVRAGINTRNVAASPDGTHVAVANYLPNTLVLLDGDLNLVKTIEAKDRDG
                     KKSSRVSAVYDATPRQSFIAALKDVGEVWEISYTKAVEDIPVSYIHDYTQREGTFIPG
                     YLNPRRTILAEVLDDFFFTQDYSELMGASREGVGQVVNLDVRKKIADLPLDGMPHLGS
                     GITWEWKDPAAGPDAKPRTVMASTNLKAGEVTVIDMKTWEVVKRIPTRGPGFFLRSHG
                     NSRYAFVDSMMSPEAKHILQVIDKHTLEVVKEITGEPGKTLAHIEFTRDGRHALASLW
                     EDEGAVIVLDAQTLEEVKRLPMRKPVGKYNVWNKITREEGTSH"
     gene            10328..11515
                     /locus_tag="P5537_02605"
     CDS             10328..11515
                     /locus_tag="P5537_02605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NnrS family protein"
                     /protein_id="HRV76965.1"
                     /translation="MALIRLDEPTTKRIPPDTFSLWALAFRPFYLLAALFAAIAVPVW
                     AVAYSGAIELPMPGIWWHAHEMIFGFAIAVIIGFLFTAGRNWTGLDTPTDKPLMVLAA
                     VWLAGRLAMAFGSGAWVAIVDLAFLPVAAGMLLKVLIKAKSKRNYFVGALPAMLALAN
                     LFFHLAVLGVIEADPLTAMHLALGLVVVLETIVGGRVIPMFTFNAVRGVKQWRNVKLD
                     WAAAIATGIALLLWALGAGAWAGVVSLVAAALQAVRLGGWNPWATRSQPILWVLQLAY
                     LWIPLGLALVALTQFGVLPRSAGIHALAIGATGGLIIGMITRTALGHTGRMLTAGRIE
                     TAAYALVLLAALVRVLTVAFIPAAQLGGVHAAATLWSIAFLLYLWRYAPYLWYARVDG
                     KEG"
     gene            complement(11667..13064)
                     /locus_tag="P5537_02610"
     CDS             complement(11667..13064)
                     /locus_tag="P5537_02610"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011236968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal sensor histidine kinase"
                     /protein_id="HRV76966.1"
                     /translation="MSHGISLTARLAALFAALTATLLVLAALLHGRMLDAHFHELDLH
                     ELHGKLVLIRNTLQQVDHATPLQARLDAVEAALVGHDNVGVRVRDADGRVLRLIHPAH
                     FSAAQRAGQAVTSEEPGWEVDGHPYLGLRGTVALPAAAAAADGGLQPQLEILVALDLS
                     HHTHFLASAQRATWAGVALAALVAAVFGWFAAHRGLAPLRRVTETARELSAERLGERL
                     DARDAPAEVRDHVEALNGMLARLETAFQRLSDYSADIAHELRTPISNLMTQTQVALSR
                     PRTSAEYQDILASNLEEYERIARTLGDMLFLAKAEENTLAHAGEVVDLASEVDALIDF
                     YEALAEERRVRILRQGRASVHGDRLMLRRALSNLISNALRHTPDGERITIAIEADTTA
                     IRLVVCNPGAPIPADQIERIFERFHRASAQRETRGEGAGLGLAITRSIVRAHGGEIAA
                     RSAEGLTRFTMTLPR"
     gene            complement(13061..13747)
                     /locus_tag="P5537_02615"
     CDS             complement(13061..13747)
                     /locus_tag="P5537_02615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004383684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal response regulator transcription
                     factor"
                     /protein_id="HRV76967.1"
                     /translation="MKILIVEDEAKTGDYLRQGLSEAGFVVDLARDGLDGLHLALEGG
                     HDLLVLDVMLPSLDGWGILQTLRRSGRTMPVLFLTARDQVEDRVRGLELGADDYLVKP
                     FAFAELLARVRTLLRRGRSPEAEVLRAADLELDLLRRRVTRGGQRIDLTAKEFALLEL
                     LLRRQGEVLPRSLIASQVWDMNFDSDTNVIEVAVRRLRAKVDDAFEPKLIRTVRGMGY
                     VLEAAEPAPR"
     gene            14028..14384
                     /locus_tag="P5537_02620"
     CDS             14028..14384
                     /locus_tag="P5537_02620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004383686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-binding protein"
                     /protein_id="HRV76968.1"
                     /translation="MKKPLRSAVCCAFAALSGFAAPVSALAQGGHSAHHGTAVATPAA
                     AELAEGTVRKIDRAAGRITIAHGPIAALEMPPMTMMFRATDPAMLDQVKVGDRIRFAA
                     AEQDGALVVTKLEAAR"
     assembly_gap    14485..14584
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            14991..16394
                     /locus_tag="P5537_02625"
     CDS             14991..16394
                     /locus_tag="P5537_02625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HRV76969.1"
                     /translation="MLALATGPGLTAALAQPPGATGELLPRHTGELPPGSTGELPPGS
                     TGELPPRHTGELPPGSTGELSPRSKGEPPLGASARSLIDQARRTNPGFAAARAEVDAA
                     RERVTPAGALPDPRFELELMDATNTMSGRSASLLPGRVGETRYRIVQPLPGWGKRELA
                     VKAAQAQVGQAEAMRDAAWVELAARIEALWLRYHAADRERGLARDALALLQGLEALGL
                     ARYELGLLPQQAVLRMQREITAQRLALVDIEQRRQGLAAGLNGLLGRAHDAPLAAPAD
                     PDPLPERLEAAALVDALASANPEVQVAANGIDRARAERERTYQDRLPDFAVGVTNNRP
                     DEGKASWDVMFEVMIPLQQSSRRAREREAEYLLMAAEARREDARARASGELGGAASMY
                     ARGRETLRLLDHTLLPQAQATRDASRAALASGTVDFDSVIEAERQLIDIRVRRLQTEL
                     ETRLALAEIKKLTGEFK"
     gene            16409..18106
                     /locus_tag="P5537_02630"
     CDS             16409..18106
                     /locus_tag="P5537_02630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015437504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HRV76970.1"
                     /translation="MTTVAVALAIAGGAGYWLARVQHGAAPATPVAVAAAAPVAGAAA
                     EAAGGGSGEDSGRGSRGGSREGSGVGPADDSRGGERQILYYRNPMGLPDTSPVPKKDS
                     MGMDYLPVYADDRPDDRGAVVVSPARIQTLGVRTAVVERRAVDATVRASGRVEIDERR
                     QVVVAPRFEGWIERLQVNAVGDVVKKGQPLFTAYSPELQSAGEELRIAERLARDSAAH
                     DPLASESARRLAEATRARLRNLQVAGQSGARQVFHAPASGVVLDKMAVEGGRFMAGEA
                     LFRIADLSRVWIIADLYEQDLARVQVGQGAQVVLDAWPGRSFAARVGYLYPTLDTATR
                     STRVRLELDNAEGLVRPGMFAQVVLAVGDATPKTVVPVSAIIDDGERRVVLRALGEGR
                     FRPQAVKLGERGREWAEVLEGVEEGERVVVSANFLIDSESQLKAALANLMALEADAAA
                     SANAAAPAARPRYDTTGRLEAVDLETRSLTLSHAPIPELRWPRMTMDFQLADPALVQG
                     VAPGSAVRFSFEVGEPGEYVVTRIEAAQAQPDAGGDVDAAGRAVPGGGSGAGAHGGH"
     gene            18093..21326
                     /locus_tag="P5537_02635"
     CDS             18093..21326
                     /locus_tag="P5537_02635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051139 - metal cation:proton antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CusA/CzcA family heavy metal efflux RND
                     transporter"
                     /protein_id="HRV76971.1"
                     /translation="MEAIEMAPSESSTAAAVPPAPPAGAATPGAANPSVASPGALDRL
                     IDWSARNVFLVLLATLFLVAGGLYAVHKTPLDALPDLSDVQVIVYTDFPGQAPQVVED
                     QVTYPLTTSMLAVPRAKVVRGFSMFGASYVYVIFEDGTDLYWARSRVLEYLSTAASRL
                     PQGVAPQIGPDATGVGWVYQYALLGRDMSLAETRSLQDWYLRYPLSQAHGVAEVASIG
                     GFVREYQVSVDPLRLAGYGITLDQVTQAIRASNRDVGGRVVELAEKEYMVRGRGYLRG
                     VEDIAGIVLKAERGTPVRVGDVARVELVPAERRGIAELNGEGEVASGIVMARFGENAL
                     EVIGHIKARLAEIAPGLPAGAEIVPVYDRSELIERAIANLQWTLLEESLIVAAVCVVF
                     LLHVRSALVAIVTLPLGILFAFIAMRALGLGSNIMSLGGIAIAIGAMVDAAIVMIENA
                     HKRLERLPAGAGEGARAAAIVHACKEVGPALFFSLLVITVSFLPVFVLEGQEGRLFSP
                     LAFTKTFAMAGAALLSVTLVPVLMLFFVRGRILPEARNPVNRLLIALYRPLIRGVLRW
                     RWATLALAVAAMAATVVPARQLGSEFMPTLDEGTLFYMPAALPGMSVTEAGRLLATTN
                     RILKTFPEVASVYGKAGRANTATDPAPLEMFETVINLKPKDQWRPGMTTDGLIAEMDA
                     ALKFPGLANSWTMPIKARIDMLSTGIRTPVGVKVFGKDLETLERLAQAVEAAVRKVPG
                     ASSAYAERVAGGYYIDIEPRRDQLARHGLSIDMLQEVIATALGGETVTTTVEGLERYA
                     VSVRYARGLRDDPARLATDVFVPTMNGPIPLGQLAEVKLTRGAPAIRTENALLAAYVY
                     VDTREADLGAFVERAQRAVAAEVAFPQGYYATWSGQFENMERAKEKMKIVVPFTLALI
                     FVLLYLNFGRLAETLIVMLSVPFALVGGVWLMWWLGYQMSVAVAVGFIALAGVAAETG
                     VIMLIYLDQAWQEMRARCRAEGRAPGVAELHRAIMEGAVERVRPKMMTVVTIMAGLLP
                     ILWGSGTGSEVMSRIAAPMVGGMVSSTVLTLAVIPALYALVKRRELG"
     gene            complement(21481..22197)
                     /locus_tag="P5537_02640"
     CDS             complement(21481..22197)
                     /locus_tag="P5537_02640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RES family NAD+ phosphorylase"
                     /protein_id="HRV76972.1"
                     /translation="MNSLFARLTLADLRRDVARNIVSLRESQDLFDDLTDNPAEWSLA
                     QQVEDAVKPPPYRSHTPVIDRPFEDSAWFNAIDWPFRHWQASRFSDGSHGVWYGSETI
                     ETTVFESAHHWYHGLLSDAGYEREAVVAERTVYWVACAAALLDFRGVTGEYPDLLHPA
                     DYAFSQSVGARIRHEGHPGLLIQSVRRPAGDNVAIFNPAVLSNPRLGCQLTYRLAGER
                     IVVEKSPGTAWMSVALTPRG"
     gene            complement(22210..22605)
                     /locus_tag="P5537_02645"
     CDS             complement(22210..22605)
                     /locus_tag="P5537_02645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2384 domain-containing protein"
                     /protein_id="HRV76973.1"
                     /translation="MGAIAERETTTSQDRGALARMVMTLLDHWKLSTEDQAALLGIAA
                     SNRAALARYRKGEAIGTSRDQYERVGHLLGIHKNLRLLFPHNRDLAYRWMSTRNKAFD
                     NLSPVEVVKEWGFAGLLMVRSYLDRARGV"
     gene            complement(22792..23271)
                     /locus_tag="P5537_02650"
     CDS             complement(22792..23271)
                     /locus_tag="P5537_02650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein tyrosine phosphatase"
                     /protein_id="HRV76974.1"
                     /translation="MDILFVGKGGDCRPLLAEAIFNHLAPCHCKARRVACDRDEPPSP
                     AALALLERQGIRPGPTTAETPSAALRAGDVLISLCSMRADHACPHRADAPLHVRWTVH
                     DPLQRHLFARRADGELLDVYHILRARIERLLPLLQPGGAQDQARLASELDRLGRFLP"
     gene            23461..24384
                     /gene="ppk2"
                     /locus_tag="P5537_02655"
     CDS             23461..24384
                     /gene="ppk2"
                     /locus_tag="P5537_02655"
                     /EC_number="2.7.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008976 - polyphosphate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006793 - phosphorus metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate kinase 2"
                     /protein_id="HRV76975.1"
                     /translation="MDNREIADLHRRIERELLDSYDEELELELDDQRFDEIGSGEAPP
                     ESADERAKRRRYFTELLRLQGELVKLQDWVATTRHRVVILFEGRDAAGKGGVIKRITQ
                     RLNPRVCRVVALPAPNDRERTQWYFQRYVPHLPAAGEMVLFDRSWYNRAGVERVMGFC
                     TDAEYEEFFRSVPEFERMLVRSGIQLIKYWFSITDEEQHFRFMSRIHDPLKQWKLSPM
                     DLESRARWERYTVAKETMLERTHIPEAPWWIVEANDKKAARLNCIHHLLGQMPYTEVQ
                     RPLVELPARVRNADYTRHPVPADMIVPAWFR"
     gene            complement(24389..25621)
                     /locus_tag="P5537_02660"
     CDS             complement(24389..25621)
                     /locus_tag="P5537_02660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HRV76976.1"
                     /translation="MSTTTVDLIYFNAGGGHRASALALEAALQRQRPSWRVRTVDLFA
                     VLDPQERFRALTGSRPEDWYNKRLARGWTLGMTQELKLLQAAIRLGHPLLMRSLQEHW
                     LRTEPDLVVSLIPNFNRALYESLAGALPGVPYATLLTDLADLPPNFWIEAGQPQHFIC
                     GTPRAVEQALALGHNTQRVHATSGMILRPEFYEPLAIDRSAERARLGLDPRRPTGLVL
                     FGGHGSRAMLGIAQRLAATTQTIFLCGHNKALAAKLRALPSAAPRLVVEFTSDIPYYM
                     RLADFFIGKPGPGSISEAVQQGLPVIVVDNAWTMPQERYNAEWIRENGLGVVHTGFRT
                     IDLAVARLLDRLEDFQASVRRIDNQALFEVPDILDAILAQASTVTRTDGFSCADHHAP
                     GATPTPDRARTRMRTGQT"
     gene            complement(25618..26388)
                     /locus_tag="P5537_02665"
     CDS             complement(25618..26388)
                     /locus_tag="P5537_02665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HRV76977.1"
                     /translation="MTAYRNPDRLVIFDADGTTIDAFHAVEQSFLRHGMAIGDLQRFQ
                     KRRRLFKYLGGLREFPNNLRRQFGKQSRKRLLATLTGFYRDEARLYPGIAPLLQQLLD
                     APEVRVGLVTRNVTVEPAETLRQLFRRHDIDLDAFDHLACLSLREDKTPHFRQARDRL
                     GIHPARCYACGDEYSDYLAALGAGMYPFIVAYGAEDRQRLTDAYGVPDAFIHASPAEF
                     ADSLRHALGFNADGDDQDARPMAPMTDTTPAPAAGSTP"
     gene            complement(26559..26990)
                     /locus_tag="P5537_02670"
     CDS             complement(26559..26990)
                     /locus_tag="P5537_02670"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012514.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HRV76978.1"
                     /translation="MAKERLSSTPPPGVWAVIHCTKTDTYLLGKRSQAVNNGGAWNLF
                     GGRVDRGEAPARALTRELAEEAGLRIKRKALRRISTIRHRDADDRELHYFLLEVEREL
                     APRLNREHSRYGWFKRRQLPSRFNLPTHVAIKHGLLEKSKA"
     gene            complement(27119..27970)
                     /locus_tag="P5537_02675"
     CDS             complement(27119..27970)
                     /locus_tag="P5537_02675"
                     /inference="COORDINATES: protein motif:HMM:NF013088.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HRV76979.1"
                     /translation="MGLTPGIALAVLAAALLHASWNALIRGAGDKRLYTLLLHAFSAA
                     LGAAGLLFTGLPAPASWPYLALSAVIHSAYIMLLIRAYEGGQLATSYTLMRGLPPLIV
                     GLLSGPVLGEALGPEGAAGIALISCGVIGIGFASGLTLARIATHPSTHAAVLNALAIS
                     TYTLVDGQGARLAGNPLAYVFFLSLLEPIGVLLAGLRRDASALRRYSLDHWRLGLVGA
                     MAAMLAYATVLWAMTRAPVAVVAALRESSVIFAVLIGALWFKEGRLQSGILAGTIVMA
                     GVFLLRH"
     gene            complement(27972..29315)
                     /locus_tag="P5537_02680"
     CDS             complement(27972..29315)
                     /locus_tag="P5537_02680"
                     /inference="COORDINATES: protein motif:HMM:NF004755.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HRV76980.1"
                     /translation="MRAEFDRSEGDVNLSDRRTAWQSTHIDGETRALLDEDARWFLHQ
                     SMSTPCLNVLEAAQGAWLTDTAGRRILDFHGNSLHQVGHGHPRVMAAMRETLEALPFS
                     PRRYTNRHAIELARRLCIAAPMEEAKLLFAPGGTAAIGMALKLARLVTGRFKTLSMWD
                     AFHGASLDAISLGGEAVFRRGIGPLLPGTEHVPPCDPAECVFGCGGTCALRCVDYIDY
                     CLRKEGDVAAVVVETIRCTDVQIPPPDYYRRLRRICDRHGALLILDEIPIALGRTGHL
                     FAIERYGIEPDMVVIGKGLGGGSMPLAALIARSRFDVGQHISLGHYTHEKNPLACAAG
                     LAVLDVIEEEQLLARSLRLGEAVMAYLERAKNQAVASIRSAGLLIGIELRDTATRGAQ
                     DLAEAVLYRCLSDGISFKVGQGKVLVLAPPLNIDEADLWWALERIVAALDAESRA"
     gene            complement(29305..30159)
                     /locus_tag="P5537_02685"
     CDS             complement(29305..30159)
                     /locus_tag="P5537_02685"
                     /inference="COORDINATES: protein motif:HMM:TIGR03338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate utilization associated
                     transcriptional regulator"
                     /protein_id="HRV76981.1"
                     /translation="MPGLLLSREGQGAGLDCQQLRGGRLQIVDNLQNGKSATLPIPTR
                     LLPLEMPALLTDPTDTALTLVQSTSLTRLVAESVEKSILSGELAPGAKLNEVALAERL
                     GVSRGPLREAFRMLEESGLIRQEKNRGAFVREIALDEAADIYEVRAGLDAMAGRLLAS
                     RITPVQLAALRSMTDRMQAAAATEDIDGFHVLNLRFHDQIVEMTGNRSLLDIYRKLVK
                     QLTLFRRRNLFAPMAIPHFADEHSAIVDLLASGDGERCAQALLTHAQGGRQRMLRDGA
                     YTEAHHAR"
     gene            30192..31223
                     /locus_tag="P5537_02690"
     CDS             30192..31223
                     /locus_tag="P5537_02690"
                     /inference="COORDINATES: protein motif:HMM:TIGR03261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009897 - external side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0033225 - ATPase-coupled
                     2-aminoethylphosphonate transporter activity [Evidence
                     IEA];
                     GO_function: GO:0033226 - 2-aminoethylphosphonate binding
                     [Evidence IEA];
                     GO_process: GO:0033223 - 2-aminoethylphosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HRV76982.1"
                     /translation="MTLKRLAQSLAALGLALSVALPAHADKSVLNVYTALETDQLKAY
                     QEAFNKQYPDIEIKWTRDSTGIITAKLLAEKGKPVADVIMGVAASSMVVFDRENMLQP
                     YAPQNLKEINPKFRDAANPPKWVGMDVWGAAVCYNVAEMQKQGLPRIESWKDLLKPEF
                     KGKVVMPNPNSSGTGFLDVTAWLQMFGEKGGWEYMDKLHDNVAVYTHSGSKPCVMAGA
                     GEFPVGISFEYRANTVREKGAPIDVIFPSEGLGWDVEAIAIVRDTPRLEAARKLADWA
                     STREANELYAKNFAVVAIPGIATRLKHVPNDYEQRLVKNDFAWMAQNRDAILAEWQQR
                     YANKSEAKK"
     gene            31293..32372
                     /locus_tag="P5537_02695"
     CDS             31293..32372
                     /locus_tag="P5537_02695"
                     /inference="COORDINATES: protein motif:HMM:TIGR03265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0033225 - ATPase-coupled
                     2-aminoethylphosphonate transporter activity [Evidence
                     IEA];
                     GO_process: GO:0033223 - 2-aminoethylphosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     ATP-binding protein"
                     /protein_id="HRV76983.1"
                     /translation="MEHLEIRNLTKRFGAFVALDQVDLAVARGEFLVLLGPSGCGKTT
                     LLRAIAGLERQDAGEIFHGGDEISQRSPALRDFGIVFQSYALFPNLTVADNVAYGLKS
                     RKADRGVGRDGVRRRVAEMLDLVGLPGIEHKYPAQLSGGQQQRVALARALATAPDLLL
                     LDEPLSALDAIERVRLRSEVRQLQTQLGVTTIMVTHDQEEALAMADRIVVMKSGRIQQ
                     VGAPRDIYRAPANDFVADFIGRGNLIEGAAAGARHVRMRNLTLRCAEPLAPGRSHRFY
                     VRPEDICLYDTLDRCENSFYAQVQKHEFLGAYSLVTLHAHDLAEQPLVAQFSSNYLAG
                     RPIAAGATLRIGIPPEHLRPMPEPA"
     gene            32369..33685
                     /locus_tag="P5537_02700"
     CDS             32369..33685
                     /locus_tag="P5537_02700"
                     /inference="COORDINATES: protein motif:HMM:NF012738.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HRV76984.1"
                     /translation="MTRLAWSLPRLGEGRSTSERLGTGLLVGAALLLCAFLILPLGVL
                     LLGSLFDEAGELSLVRFAEFASTPGMGRAVWNTIWVAVVVTVLTVPLAFLYAYAIQRA
                     CLPLRGVWRIVGLSALLGPSLVGAISFIQWFGTQGVLKSWLGEHSVYGPIGIIISTVY
                     ASFPHALMILVVALATADARLFEAAEALSASRWRKFVTVTLPSARYGLISAALVVFSY
                     SVSEFGIPKVIGGNFPVLAVEVYVQVVGMHNFGRGAVVALLLLFPVLLAFLVDWRIQR
                     KQQASLTARAVPYVPRPDWRRDLPLLAYCVLVSVAMLGVLGMAAYTSLVKFWPYNLEL
                     SLTHYRYGLAEAGVLDAYLNSLKIAGLTTLVGTPFIFLVAYLVEKNRSGPAWLRPLVQ
                     GAAALPMGVPGLVLGIGYILFFNHPSNPLNGLYHTLAIMVIANVVH"
     gene            33728..34072
                     /locus_tag="P5537_02705"
     CDS             33728..34072
                     /locus_tag="P5537_02705"
                     /inference="COORDINATES: protein motif:HMM:NF012738.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HRV76985.1"
                     /translation="MDREFEAVSASLKVSQFVTLWRVTLPVCLPAVLEIARYLFINAM
                     TTVSALVFLYSPETLPASVSILNLDEAGELGPAAAMATLIVLTCALVSLLYSLLTHFL
                     FRRQQAWRNPNR"
     gene            34088..35209
                     /locus_tag="P5537_02710"
     CDS             34088..35209
                     /locus_tag="P5537_02710"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: protein motif:HMM:NF010006.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HRV76986.1"
                     /translation="MYSTDRDPLLLTPGPLTTSLRTKQAMLHDWGSWDAAFNRVTGEL
                     CRQLVDIVHGADTHVCVPLQGSGTFSVEAALGTLVPRHGKVLVPNNGAYCARIVRILG
                     YLGREAVELPFPEDCPADPAAIEAALLADPAITHVAQVHCETGTGILNPLAGIAAVVA
                     RQGRGLIVDAMSSFGAIDIDLRSLAIDAVVAASGKCLEGVPGMGFVIVRRAALEAAAG
                     NCHSLALDLHDQWAYMQKTTQWRFTPPTHVVAALHEALAQYREEGGLAVRGARYARNC
                     VALIEGMRGLGLRPFLAPEVQAPIIVTFHAPAHPAYDFKAFYERVRERGFILYPGKLT
                     RVETFRVGCIGALGGADIEKVVAAVGETLREAGIVLGAG"
     gene            35206..36444
                     /locus_tag="P5537_02715"
     CDS             35206..36444
                     /locus_tag="P5537_02715"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013434.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HRV76987.1"
                     /translation="MSADLDRARDILIIGAGIFGAAIAWSLARQGQGHRVTILERGHP
                     AGGATSRAAALVTQIRDDPVLVALARETFLAMQALEAEGEHLGRHHAGALHVVSRQGA
                     EALSQRAEAAAALGIRSERPSRAEVQARAPWLRRQAGDCAVFFPEDCYVDPYLLASAY
                     LKAGVRGGVRLMRDADVRHVLHADARVTGVELSDGRRLEARVVINAAGAWANLLSVEL
                     GLPLPMAPVRSHYWITEQAPIFPRNGAIVFMPEIRAYARPEVGGLLFGIRERSPAVVD
                     ARKLPADLSGFVFDPADADGWESLAEGADPLEGFFPAVRSLRIAHYVTGPSNYTDDAQ
                     LILGASRRIDGLFVASGCNGSGITFSGGVGRLLAELVLHVSPFISSARFDPARHAPFD
                     PYAPAFLARCAATRAGKASG"
     gene            36480..37292
                     /locus_tag="P5537_02720"
     CDS             36480..37292
                     /locus_tag="P5537_02720"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: protein motif:HMM:NF010005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050194 - phosphonoacetaldehyde hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HRV76988.1"
                     /translation="MQHRLEAVIFDWAGTTVDFGSFAPTQIFVDAFRQAFDFELSLAE
                     ARGPMGLGKWQHIEALGADPVVGARWQARFGRPMSHADIDHIYRTFLPLQVERVAAHA
                     DLIPGTLETIAAIRGRGMKIGSTTGYPRQVMERLMAAAEAKGYAPDCTVCADDLEAGA
                     RPGPWMALQCVLDLGIGSVARCVKVDDTLPGIAEGIHAGMWTVGLALSGSPAGLTLAE
                     YETASAEERRAVRERVTPAFVEAGAHFVIDTIAELVPVLDEIEARLGRGERP"
     gene            complement(37395..37598)
                     /locus_tag="P5537_02725"
     CDS             complement(37395..37598)
                     /locus_tag="P5537_02725"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76989.1"
                     /translation="MQRTLDPLDQAAANSHRFITGDAHRSTLHYQGARALPKPRIADL
                     IDDGDALTEWHRNMAKLRERHKV"
     gene            37894..40752
                     /locus_tag="P5537_02730"
     CDS             37894..40752
                     /locus_tag="P5537_02730"
                     /inference="COORDINATES: protein motif:HMM:NF014069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing phosphohydrolase"
                     /protein_id="HRV76990.1"
                     /translation="MPGHSGRIPQRSSPVRSTPLRLPLHIPVAVLFSLLILGVGATIS
                     LHHFRETSALLEAANQRLFRALAEDVRAALEDVERSVRRAFILLSTSPLADAAGFAER
                     LRFLPELTGLMAADPLIDSVMVGYGDGGFFLLTRASASQTGRGEAVWTLLDAGRSEQH
                     DAPPVPLEYRFDRDLRFLGSSPASAAPSEPRLTDWYRRAAASNALIVSPPYALRHSGS
                     RGLTFAQRNGAAVVGINVDFAALSLAMSRESAIPSTLVRLLARDRSVIAGHTAPAGAG
                     APEGDVLITRALDAPAGDGSSTRVLEDAAGRSWHVSLAPLAGLGDDGWTLAVAVPDDE
                     IFAEALRQRERSILFTIVAVLLSLPLAWGLSRLLTKPLHRLSGVAHAVSALQFRSGAE
                     THSIILEVDRLAGAIAMMQATIARFIELGRDLGTARDVRSLLLEVRAGAREVAQVPWC
                     AVHVFALHRSGAGWLDASDGSDSLPEELDWSRLPDPQAAGDGPFSVRIPASAGAAWQV
                     LLIPLQIGNGQRLGTLVLTDRAAAASSLQRSEVVGFLAALAGSAAIALENQRLLDGRK
                     DLLHGVMRLIAEAIDAKSPFTGGHCRRVPQIATRLARAAHDFDRGPLAAYRLDASGWE
                     ALQMGAWMHDCGKLTTPDYVIDKATKLETLHNRIHEIRTRFEVLKRDAEVAYWKGVAQ
                     GLDEGTLRQRRDTAWQVLDEEFAFVARCNVGGEAMTEADAERLRQIARRRWMRTLDDG
                     LGLSTAELERRAHLPERPPPAEEALLADRPEHIVPRQDSTRFAPGNPWGFSMRPPAAL
                     YDRGELHNLTVARGTLTAEERFKINEHIVETILMLERLPFPPDLASVAEIAAGHHETM
                     DGRGYPRGLCAAALSVEARIIAIADIFEALTAHDRPYKTAHSADEALAIMRTLCARRV
                     IDPDLFELFVACGAWRDDAAAGGEAATAASAMQPPDAH"
     gene            complement(40807..41337)
                     /locus_tag="P5537_02735"
     CDS             complement(40807..41337)
                     /locus_tag="P5537_02735"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76991.1"
                     /translation="MNEEIQATPKTDEAPATAAAPAAVPPQTEAPVPATPKSPAKPAA
                     KAKPRKAPAPVASAAPDASKPAPARKRAAPPVKNAAAVDAPAPAEPPKATKATKAKKH
                     APAKPKLVRDSFTLPENDYALFASLKQRALKSGAEVKKSELLRAGLAMLALADDAAFL
                     EAVGRIERIKTGRPKK"
     gene            41416..42042
                     /locus_tag="P5537_02740"
     CDS             41416..42042
                     /locus_tag="P5537_02740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011286316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HRV76992.1"
                     /translation="MRRIMVANPKGGSGKSTLAVHLASWFARNDELVYLGDLDRQQST
                     ARWLAGRPRSLAPIRHWDIAGDEFDAPPKDCTVAILDTPAGLHGKRLKLALSAMDRIV
                     VPVSPSRFDMLASRDFFEELAETKAVRKDRVDIAIVGMRVDPRTNASRLLVEYLQQFD
                     LPLIACIRQSQRYVQAVETGVTLFDGNRIDPVDQLHWRPLLDWLVRRR"
     gene            complement(42113..43057)
                     /locus_tag="P5537_02745"
     CDS             complement(42113..43057)
                     /locus_tag="P5537_02745"
                     /inference="COORDINATES: protein motif:HMM:NF017085.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAD domain-containing protein"
                     /protein_id="HRV76993.1"
                     /translation="MVQDQDRGIPEAGQPQPLHAETSPLQRGLTVEEAFVALARSCVR
                     QWQGNVAGASHAEADQAAEFIHQIRVALRRLRSAMKVFAPALPSAFTETWPQRLRDNA
                     DRFGPARDLDVLRTELLDAIAPEWLIGTVAFRDLVDVVDRERHTANEAAKRALDPEEQ
                     ARIALAFNADLLQLPRRGPAPGLELTEFARERLVRARRRARERFNAASSLEPAQLHRL
                     RIGLKDLRYAVEFFAPLLGRKTVRSYLERLTQAQTTLGFLQDLEVARGRLEIWAHAAP
                     SLSLAAGFVLGWHGPRYSGLRSRVLEETRPVLWGRTPW"
     gene            43237..45018
                     /locus_tag="P5537_02750"
     CDS             43237..45018
                     /locus_tag="P5537_02750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HRV76994.1"
                     /translation="MAVTFEADNGGFIQKLTVARCSTDVVPARAASADLAASVRTESW
                     KRFMSIRQNLVVLIVITATLLLSIGVIGKTQFLRHDEMTRTLTDNAIPGALVAADLVA
                     DLKQAELDLIELVFAPDPDIAAKAQERLRIQQERVSANLDTLERLPSTAKESGLLEHA
                     RQRLADYRAATDEVLAYARAGQRVLAEASLYANVAGYKDELQQVLGDLRVEKGRSKDA
                     SVVAVREELARTMRVLGWAGGVTLLILVALVSRLHRSIVRPLRAMEATMTDIAVSLDF
                     TRRVAVSRNDEIGQSVRAFNSLLDTLQHSLGAIVGIIRSNESATAEMHQSALVVADIA
                     AEGGDASKRIQHAVQSIEQHILEIDRESRQAGRITEASSQEASSRSAVIRETANRIDA
                     LAAHIDAASAQVFALAGEVGEIESVVTEIRQIADQTNLLALNAAIEAARAGETGRGFA
                     VVADEVRKLAERSAAATELINQRIGGIRRASHDCTGLMQRVGVEMEQSTSLARSAGEA
                     IESIEQSATRVIDVVGEIIRLVQIGQRSGGEIVAQVGTIDVLLDRAQQAAAHTKLAAD
                     HIRGISRDLATIVARFRIEQPSGSAAG"
     gene            45304..46131
                     /locus_tag="P5537_02755"
     CDS             45304..46131
                     /locus_tag="P5537_02755"
                     /EC_number="1.13.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051213 - dioxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class III extradiol ring-cleavage dioxygenase"
                     /protein_id="HRV76995.1"
                     /translation="MQALPTLFVSHGAPTFALEPGLAGANLAALGRRLPRPQAVLVVS
                     PHWMTRQAQATLSLRPETIHDFGGFDPALYTLQYPAEGAHLAARRALELLQAAGLPAT
                     PNADRGLDHGAWVPLMHLYPEADIPVFQVSLPEWLDADGAYGYGRALAPLADEGVLIV
                     GSGSLTHNLYEFRLGDPRAEAYAAEFAHWVCDAVLAGDHARLRQALAIAPHARRAHPT
                     AEHYLPLLVAAGAAAQALPASVIEGGIVHGVLSMDSFLFGSDLRLMQGADANKALPH"
     gene            complement(46248..48035)
                     /locus_tag="P5537_02760"
     CDS             complement(46248..48035)
                     /locus_tag="P5537_02760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004336481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HRV76996.1"
                     /translation="MLYNAGLTLKLRQILDQDKLRFVFQPIVDIARSTVLGYEALMRG
                     PAGTPLERPDELLRMAKACNLGLELEAVACKGAIQAFAGLHKLFLNLSASSIAAFGRE
                     GGGALLRCAVDTGLPPSRLILELTEHERVDDADALRAAFATLSGQGVGLALDDFGDGR
                     SSLRLWAELKPQIVKLDKFFVRGIHLDSRKVQVVRAILDLCTTFGTPLVAEGVEVAEE
                     LAVLRDLGCHFGQGYLFARPTASPAAEIGKEARAVLSSSKISVLPNSSPRPDIADTIG
                     RLKVPAPTVCSSMSNADLMQLFTNHSELHAVAVVDKHYPVGLVNRRGFVDKFAQPYSR
                     ELYGRRPCTLFMNATPLRVEATATIDSLIPVLSGDDQRYLYEGFIITEDGRYAGLATG
                     ESLVRAVTERRIEAARHANPLTFLPGNIPITEHIRRLLDSQVPFAAAYFDLNNFKPYN
                     DLYGYWRGDEMIKLAAQVIVKNADLSQDFVGHVGGDDFVALFQSENWRERCKAAVQDF
                     NLRARALFDGPELASNGFESEDRRGFKTFFPLTTIAAGIVEITDGQFMSPEEVASAAA
                     VAKKAAKESGSGIHVGTQPRLRVLASTAS"
     gene            complement(48415..48490)
                     /locus_tag="P5537_02765"
     tRNA            complement(48415..48490)
                     /locus_tag="P5537_02765"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(48455..48457),aa:His,seq:gtg)
     gene            complement(48534..48610)
                     /locus_tag="P5537_02770"
     tRNA            complement(48534..48610)
                     /locus_tag="P5537_02770"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(48574..48576),aa:Arg,seq:tct)
     gene            complement(48638..48714)
                     /locus_tag="P5537_02775"
     tRNA            complement(48638..48714)
                     /locus_tag="P5537_02775"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(48678..48680),aa:Pro,seq:tgg)
     gene            complement(48787..50085)
                     /locus_tag="P5537_02780"
     CDS             complement(48787..50085)
                     /locus_tag="P5537_02780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV76997.1"
                     /translation="MMGPGLSYDDTPPFSAPVRFFLTAPLFGVVAGLTLLFGGEILVS
                     RWTPGALAITHLFAAGFMLQVMLGALLQVMPVVAGASMPAPLRIAGVTHVAMTLGTAG
                     LAYGLGAGAPDVLLGGAVLLVGGLFVFLSAAALGLSRGARTGNNTRTPRDLRMAFAGL
                     VVTAALGFSLVLVLTRGLALPVPLPTVVNLHAGWGWMGWAAVLLAAASWVVVPMFQIT
                     AAYPQRFTTLWAPAVTATLVLWTLAEYFAIDTARFIAIIALGLLGAGYAGTTLYLQAH
                     SRRSKPDTPFLAFREAMYAALAGVLVLVISLWSDADWWPILAGVLILHGGFGGTITAM
                     LYKIVPFLAWLHLTQAGLKAPNMKKLLPDTPIRRQLRVRSASLATLCLAVFVPILAPV
                     AGIVLAVEFGWLFANLLRVVRARRDAAKAAVPRPGSHAST"
     gene            complement(50082..50300)
                     /locus_tag="P5537_02785"
     CDS             complement(50082..50300)
                     /locus_tag="P5537_02785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2249 domain-containing protein"
                     /protein_id="HRV76998.1"
                     /translation="MSGRVVDARGLEPPEPFERAMEGLMALAKDEEMLLILDRMPHPL
                     LRILDRDGYGHTEAFRDDGAVEIRIRQR"
     gene            complement(50297..50755)
                     /locus_tag="P5537_02790"
     CDS             complement(50297..50755)
                     /locus_tag="P5537_02790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004311660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043169 - cation binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemerythrin domain-containing protein"
                     /protein_id="HRV76999.1"
                     /translation="MNTISELMTHDHRDCDGIFARAEELASDGDWADAAAALKKFADA
                     LNAHFDAEESTLFPAFEQATGMTQGPTMVMRHEHQNMRDTLAALQYALDKQDADDFAG
                     EAETLLIMMQQHNMKEESVIYPMLDSRLPGDEQERLSASVGKHLVEARAA"
     gene            51003..52205
                     /locus_tag="P5537_02795"
     CDS             51003..52205
                     /locus_tag="P5537_02795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HRV77000.1"
                     /translation="MRVFLPFALGYYLSYLLRTVNAVISPRLTDELGLSAASLGLLTS
                     AYFLAFGAAQIPVGIALDRFGPRRVEAALLLLAALGSALFATADSLGALAGARALVGL
                     GVSACLMAALKGFALWYPPERQSSMIGFIMAAGSLGALTASVPLEAVLPVLGWRGAFW
                     IIAAVCLLAAVLVLRALPDSPAAAGEPSLAAALRVVAGIFAAPAFLRHAAASVFFVGG
                     FMALQSLWVVPWVMNVNGFDLAGAATVLVALNLGNLAGQLSVGFFGVRLARAGVEPVS
                     LLRAGYGAMLVVQGLILWSGLPVLLLWTLFGLLTAANSQIYLSAARAFPPALFGRVST
                     ALNLMAFAGAFAVQWGFGIGLDFMRDGGVELTRALAFGFGGLLVLQLFAYMPLLGHVA
                     AHRREGGA"
     gene            52375..56187
                     /locus_tag="P5537_02800"
     CDS             52375..56187
                     /locus_tag="P5537_02800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF748 domain-containing protein"
                     /protein_id="HRV77001.1"
                     /translation="MPEPTTDSTVQPPRRKGMRRTLWTVAILLALSAAAYLAVPPVAR
                     HYTQKLLGETLGREVVVERVLINPFRLTAEVGGLRIMEADGSTEALGFESLRANLELE
                     SVLRKGIVLHELALDKPRVHLALEADGRHNWTDVLERIAALGGEEPAEDVPPTLFSIG
                     NIRISDGLVRVDDRVRGITHELSELGVGVPFVSNLPVRVDVFVQPSLSAKLNGDALLL
                     NARTKPFAESQETILDVALKEFDLTPWVAYLPIEPRFRLPSALLTTNVELSFSQQADG
                     APVLSLRGPLQVDRLVLQDRDGAPVASADEVELEFADVQPMIGRWHFTRLRLARPEID
                     LVRLKDGGLNVLGLIPPPAAEGARKKGKAASATVDKAAAPVAKEPVEPAVAAARAGTP
                     PAVSADGKTVADASAAAPAAPATPAGPDFLLALMRIRDGVLRFEDRSLAEPFRARIEA
                     INLDMRDLATEGELPAEIRLDYVSDAGEKFTHEDVLRLSPFQYSGSLQFESIRLPRYA
                     PYLAAAMPGASIGEGSLSGGAQYRVTLGKDGAPAVEVSSEALALRDFALVLKGAKTPA
                     LSLPALDVRSATVDLAGRSVRIGGVELKGAAVSAVRAKDGEFDLVKALVPPPGKADKP
                     AAPAAKVKAEPDWVVAVDKLALRGASVRLDDRSVARPVVTTLEGIDFELDGFSTEKGD
                     SIQFKLDSRLNKRGKVAASGPLTIAPLKADLALDLRSVDLLPLQPYVLEQTKIAISRG
                     NLTTKGRLKLDTDRRGKLLASFNGDVGVANFASVDRLNATDFLRWRTLAIGGIDARLE
                     PFSLGVKRIALDDFYTRLILDNQGRLNLREIGGVKGEPEPAAKPAAAVARTTELDEGG
                     VQAEQRAEGQRTAPVAPPGPPPPPVRIDRIELKRGNVAFSDRFIRPNYDANLTGLAGT
                     ITGFSTTSDKLAKVDISGKVDKSAPLSITGELNPFRQDAHLDILASVKDFELTGLSSY
                     SGKYVGYGIAKGKLSAELNYKIIERQLTATNRIFLDQLTFGDKVDSPDAVNLPVQLAV
                     SLLKNSRGEIDLRLPVTGTLDDPQFSVFGLVMKMLFNLIGKAITSPFALLGSALGGGE
                     ELSQLDLAAGTAAVGEAEQGKLKTLAQALVDRPALRLDIVGRADPATDLDGLRQAALI
                     NAVRAQKLKAMIAKGQAAPSLEEVEVGEAEYAELLKKAYRAADFKKERNMIGMVKDIP
                     VPEMEALLRANAQVGDDDLLALARARAQAVRDWLAGEGGVPGERIFVLEPKVEALGEG
                     GEVQFSLR"
BASE COUNT         8538 a        19092 c        19744 g         8834 t
ORIGIN      
        1 ccctgcgcga cgcgggcaag ctggccctgg tcgacggcga cacccacaag atctggaaga
       61 tcctcgatac cggctacgcg gtgcacatct cgcgcctgtc ggcttcgggt cgctatgtgt
      121 acaccgtcgg tcgcgacggc ctgaccacca tcatcgacat gtactacgaa gagcccacca
      181 cggtcgccac cgtgcgcctg ggttcggacg cgcgttcggt cgacacctcg aagttcaagg
      241 gctacgagga caagtacctg atcggtggca cctactggcc gccccagtac tcgatcatgg
      301 acggcgagac cctcgagccg atgaagatcg tgtcgacccg cggcaacacc gtcgatggcg
      361 actatcaccc cgagccgcgc gtggcctcca tcgtggcctc gctcaccaag ccggagtggg
      421 tggtcaacgt caaggaaacc ggcatgatcc tgctggtgga ctacagcgac atcagcaacc
      481 tgaagaccac cacgatcgag tccgccaagt tcctccacga cggcggctgg gacgcttcgg
      541 gccgctactt catggtcgcc gccaacgcgt cgaacaaggt cgccgcggtc gataccaaga
      601 cgggtaagct cgccgccctg gtcgacaccg ccaagatccc gcacccgggt cgtggcgcca
      661 acttcgtcca tccggagttc ggcccggtgt ggtcgaccgg ccacctgggt gacgcggtcg
      721 tctcgctcat ctccaccgct tccgacgatc ccaagttcgc caagtacaag gcgaacaact
      781 ggaaggtcgt gcaggagctg aagatgccgg gtgccggcaa cctgttcgtg aagacccatc
      841 cgaagtcgaa gaacttctgg gccgacgcgc cgatgaaccc cgagcgtgag ctcgccgaag
      901 ccgtgttcgt gttcgacaag gccgacctga agaaggagcc gatccgtctc gacgtcgcca
      961 aggactcggg cctgcccgag agcaaggcga tccgccgtgc cgtgcagccg gagtacaacg
     1021 aagcgggcga cgaagtgtgg atctcgctgt ggggcggcaa gaccgaccag tccgcgatcg
     1081 tgatctacga cgacaagacg ctgaaggtca agaaggtgat caccgacccg gcgatcgtca
     1141 cgccgaccgg caagttcaac gtctacaaca cgatgcacga cgtctattga tcgatcttcc
     1201 ggtcaagctt tgaaaaaccc ccgcgcccct ggcgcggggg accgagggga agagttccat
     1261 gtctgaacaa aacagcgaca actccaaaca agaaaattcg ggcggcctgt gggcacgcct
     1321 gcgccgtcct tccggtaagt cgctgggcgg tctgttggct gttggattcg tggtgggcgt
     1381 gctgttctgg ggtggtttca acaccgcgct ggaagccacg aacaccgaga agttctgtat
     1441 ttcgtgccac gagatgtatg acaacgtgta catggaatac aaggaaacca ttcactacaa
     1501 caaccggacg ggcgtacgtg cgacctgccc ggattgccac gttcccaagg actggacgca
     1561 caagatgatc cgcaaggttc aggcgtccaa ggaactgtgg ggcaagatgg tgggcaccat
     1621 cgacacgcgc gagaagttcg aggccaagcg cctggagctg gcgcgcaacg agtggaagcg
     1681 catgaaggcc tccgactcgc gcgagtgccg caactgccac agcttcgaaa gcatgaacaa
     1741 ggattcgcag aagcagcgcg cgcgcaagca gcacgagatg gcgctcgagg acaacatgac
     1801 ctgcatcgac tgccacaagg gtatcgccca ccacaagccg gaaggcatga ccgaggaaga
     1861 cgaggagtaa gatccctcgt gcatcacagg ccaacccaag cacagcgagg atatgacgat
     1921 gaaaaaaacg atgattgccg gcgccgtcgg tgctctcctg gctctcggta cgggtagcgc
     1981 gctcgcggct gcgcccgact ggagcaaggt ggagggcaag gacatcaccg ccttctatcc
     2041 cggcgtctcg ccgatggagt ggatccagaa ggggaccgag cacggtggcg cgcgcgcact
     2101 caagaagggc gagacctgtg ccgactgcca tagcgacgag gcggcggaca tgggcaagaa
     2161 gatggccagc ggccagaaga tcgagcccac cccgatcgcc ggcaaggccg ccttcatccc
     2221 ggtgaaggtg caggccgcgc acgacggcga gaacctctac gtccgcttct cctggaagca
     2281 gccggctgcc tcgggcgccg cgaagatgga cgacaagaac ccggtcaaga tcgcgttcat
     2341 gctcgagtcg ggcggcaagg tcgaactcgc cgaccagagc ggctgctggg cgacctgcca
     2401 cactgattcg cgcaccatgc cgggcgcgga cgaggccaag accaagtacg tcaagggcgg
     2461 ctcgctcgcc gagggcaagt tctacgatct ctaccagtgg cgtagcggcg agaacaaggg
     2521 ctacaacggc tacgtcgccg acaagcgcgt gatggaaggc ggcaacgccc tggtcagcgc
     2581 cgaaggcaag aaggacggcg acagctggtc ggtggtgttc actcgcaagc tcgccgccgg
     2641 cgatggcgac gtgaagctcg agtcgggcaa ggcctacaac ttcggcttcg cgatccacga
     2701 cgacaacgcg gcgggccgtt tccaccacgt ctcgctcggc tacaagctcg gcctcgacac
     2761 cgatggccac atcaaggcgg ccaagcagta acccgacctg atcccgcccg cgctcccggg
     2821 cggtgttcga tacggcggaa gcatccggcg aacccggggc ttccgccgtt gtcatttgcg
     2881 atggatccat cgcgaccttg cggtcgcctg tgcctgaaac ggagatgtcg atgaatgcga
     2941 gattcgcccc cgcctgcctg cttgccgccg ccttttcgtt cgctggcggc agtcctgctt
     3001 tggctgcaga gcatcaggtc atcgtggaga agtatgcctt cgcaccgatg gagttgcgca
     3061 tcaagcgcgg cgacaccgtg acctgggtga acaacgagaa gcgggtgagc cactcggtgc
     3121 tgatgatcgg gcgcagcgag gagtccgagc gcttctttcc cggtgagaag tggtcgcgcg
     3181 ccttcccgga agcggggcgc ttcgagtacc gctgcggccc gcatccggaa atgctcgggg
     3241 tggtgatcgt agaggactga ttcgcgccgt cgcacccgcc cgccgccacc gccgcagctc
     3301 gcgcaagcga cggaggagcg cgggcagatg gggccggcgg aggcgctaaa gctggcgcag
     3361 cggtgcgggc aagaccctgt gtccgtcgag gttgattcga gtcaaggttt cgacacggtc
     3421 gagaggccat gctccgtccg aagccttacc gccggatgcc agcatgaaga ttccgccact
     3481 cctcgcccac gccgtggtcc tcctcggcgc tgcgctcgtc tccgcctatg ccgcggcatc
     3541 cgagcgcgca cccgtcgaac ccgatccggc gcgcgcgcgc gaactgatcc acatcgtccg
     3601 ccaggactgt ggctcctgcc acggcctgac tttcaagggc gggctcgggc ccgcgctgac
     3661 ggccgaggcc ctggccgaca agccggccga agggctcgtg gccaccattg tcggcggccg
     3721 cccgggcacg ccgatgccgc ccttccagac catcctgtcc gaggccgagg ccgagtggat
     3781 cgtctactgg ctgatgcgcg gtttccccgc cgacgccggc ctgccgcagg ccgccgcacg
     3841 caactgaacc atcgccgtcc gtgctccagc gactcgagcg ggcgtggacg gcagtctccc
     3901 cggtggcggc ccgccacccc aagctcccgg agtttccatg tcttcccgtg aagttcgact
     3961 cgcaccgccc gccctgtggg gcgtggtcct ctccgccatg gtcgtgctgc tgtcggcctg
     4021 ttcgagtacg ccgcctgccg ccttgcgcgg caccggcgac ctcggcgtgg tgatcgagcg
     4081 cgccgacggc aaggtgaagg tgatcgagac caccgggcgc agcgtgctcg ccacggtggc
     4141 cggcctgggc gatctctccc acgcctcggt ggtgttctcg cgcgatggcc gctacgcctt
     4201 cgtgttcggc cgcgacggcg ggctgaccaa ggtcgatctg ctcgagcgtc ggatcgtagg
     4261 ccgcaaggtg caggcgggca acgcgatcgg cggctcgatc tcgcacgacg gcagcctggt
     4321 ggtggtgcag aactacgagc cgggcggcat caaggccttc gacgccgaca cgctcgaact
     4381 cgtcgccgac gtgcccgcca ccaccgagga cggcacccgc tccaaggtgg tgggcctggc
     4441 ggacctgtcg ggcaagcgct tcatctactc gctcttcgag gcgggcgaga tccgcatcac
     4501 cgacttctcc gaccccagga agccggtcac ccagcgtttc gccggcggca agcagcctta
     4561 cgacgcgctg gtcacgccca acggccgcta ctacatcgcc ggcctcttcg gtgaagatgg
     4621 cctggcgctg atcgacctgt ggaacctcga caagggcagc cgcaagatcc tctccggcta
     4681 cggccgcggc gagcagcccc tgccggtctt caagatgccc cacctgcgcg gctggtcggt
     4741 cgccggaaac cgtgcctacc tgcccgcgat cgggcgtcac gaggtgctgg tggtcgacac
     4801 ggacacctgg caggaggtcg atcgcatcaa ggtcaagagc cagccggtgt tcgccatggc
     4861 gcgtccggac gggcgcgaga tctgggtgaa cttcgccttc ccagacaatg gctgggtgca
     4921 ggtcatcgac accgtcagcg gcaaggtcac cgacaccctg cagccgggcc gcggcatcct
     4981 gcacatggag ttcctctcca aggggcacga gatctggctg tcggcgcgcg acgacaacaa
     5041 ggtcgtgatc tacgacaccg ccagcaagca gcagatcggc ggcttcgact cggcgagccc
     5101 gagcggcatc ttcttcacca cgcgcgccgc gcgcacgggc ttctgatgcc gcgccaggcc
     5161 atcctgcccg aggcgctcga cgccaccggc ttccgcctgc tcaacgagtg gcagcgcgac
     5221 ttcccgctcg agccgcggcc cttcgcgcgc atcgcgcagg cggtgggcgc cgccgaggag
     5281 gacgtgatcg cggcctaccg cgacctggcc gcgcaaggcc tggtgagccg ggtgggcgcg
     5341 gtgttcgccc cgcgccgcct gggcgcgagc gcgctggctg cgctggccgc gccgcccgag
     5401 cgcctggagg aggtcgccgc gcgcgtcacg cgcgaacccg cgatcaacca caactaccag
     5461 cgcgagcatc gctacaacct gtggttcgtg gtcaccgcgg cctcgcgcgc gcagctcgac
     5521 gaggtggtcg ccggaatcga gcgcgacacc ggctgcgcgg tcatcgtgct gccgctggaa
     5581 gaagagttcc acatcgacct cggcttcgac ctcaaggcgg gcggggcggg gcggcgctcg
     5641 cacgcgggcc cgcgcgccgg cgagccgatc gcgctcggca acgcggacgg cggctgcgag
     5701 ctgccggcgg tcgaacgcca gttgatcggc gcgctgcagg gtggcctggc gctggaggcg
     5761 cggcccttcg ccacgctggc ggcgcgggtc ggtctcactg aggatgcggt catctcctgc
     5821 atcgcgcgct gggtggacga aggcctgatc cgccgcttcg gcgtggtcgt gcgccaccac
     5881 gagctcggcc tcgaggccaa tgcgatgtgc gtgtgggacg tacccgacgc cgaggtctcc
     5941 gcgctcggcc gccgcctcgc gcaggaggcc gcggtcacgc tgtgctaccg gcgcagccgc
     6001 gtgctgcccg actggcccta caacctgttc tgcatgatcc acggcagcgc gcgcgaggag
     6061 gtgctcgccg cgcgcgacga cctcgccgtg cgtctgggcc tcgaccgcca tccgcatgcg
     6121 gtgctgttca gctgccggcg cttcaagcag accggcgcac gctatctcgg cgccaaggac
     6181 ctcgcccatg tctgaagccc attccgccgc ggtcgccggc cgtcgcggcg tcgccgcgaa
     6241 gcgtccgccc gacgaggtcg agcgccgcct gatcaacgcc atccagggcg agttcccgct
     6301 ttcggaacgc ccctttgccg aggtcggggc cgcgctcggc ctgtccgagg acgaggtgat
     6361 cgcgcgcctg cagtcgcttc tcgacgaccg cgtgctgacg cgcttcgggc cgatgtacca
     6421 gatcgagcgc atgggcggcg ccttctgcct ggccgcgatc gcggtgcccg aggcgcagtg
     6481 ggcgagcgcg gtggaggcgg tcaacgcctt ccccgaggtg gcgcacaact atcgccgcga
     6541 gcatgcgctc aacatgtggt tcgtgctcgc caccgagacg cccgaaggca tcgccgactg
     6601 cgcgcgccgg atcgaggccg cgaccgggct ggtggtgcat ctgttcccca aggaacgcga
     6661 gtacttcgtc gagatgaggc tggtggcgtg atgacgagag acatgccgga taacgcagcg
     6721 ctcgtgcggg ccgacgcccg cgacgaggcg gccaggagcg ccgatgaagc tgcccgcgtc
     6781 gaactcgacc gccgcatcgt gctcgccacc cagggcggcc tgccgctggt ggcgcgtccc
     6841 tacgccgcgg ttgccgagac gctcggcgta gccgaggggc tggtgcgcga gcgcctcgcc
     6901 gccatgctcg ccgacggccg catccgccgc atcggcgcgg tgcccaacca ctacgcgatc
     6961 ggctacaccg ccaacggcat gagcgtgtgg gacatcgatg ccgccgtgat cgacgcggtc
     7021 ggcgagcgcg tcggcggact cgacttcgtc acccactgct accgccgccc ccgccacctg
     7081 cccgactggc cctacaacct gttcgccatg gtgcacgccg ccagccgcga ggccgcgctc
     7141 gcacgcgtcg aagagatcgc ggcgctgatc accgcggagt ttcccggtgc ctgccgcggc
     7201 tgcgacgtgc tgttctcgtc cggcatcctc aagaagacgg ggctgcggat cggcggctag
     7261 gcacatccgg cgcgccggtg tttctgcatg cgcccaaggc ctttctgccc gcgccgggca
     7321 cccttgacgc gcatcatttt cattcgcggg cgcctcgggt gaaatggcct ccattcagga
     7381 ggctcccatg ttccgcatct cccaattcat ccgcgagctc gaccacccca cgcccgccgg
     7441 cccgcgccgc aacccgccgg gcccggtggt gatctggaac ctgatccggc gctgcaacct
     7501 cacctgcgag cactgctact cgatctcggc ggacaaggat ttccccggcg agctgaacac
     7561 cgaggaggtg ttcaaggtca tggacgacct caaggccgcg cgcgtgccgg tgctgatcct
     7621 gtccggcggc gagccgctgc tgcgccccga catcttcgac atcgcccgcc gcgccaaggg
     7681 catgggcttc tacgtcggcc tgtcgtccaa cggcaccctg atcgacgaat ccaacatcga
     7741 cgccatcgac ggcatcggct tcgactacgt gggggtgagc ctcgacggca tcggcgccac
     7801 acacgaccac ttccgccgca aggagggcgc cttcgaggcc tcgatgcatg gcatccgcct
     7861 gtgccgcgag cgcggcatca aggtcggcgt gcgctacacc atgaccgagg gcaacgccca
     7921 cgacctgccg gcgctgctga agctggtcga ggacgagcac atcgacaagt tctacttctc
     7981 gcacctcaac tacgccggcc gcggcaacaa gaaccgtgcc ggcgacgcgc accatcgcac
     8041 cacccgcgaa gccatggagc tgctcttcga gacctgcctg gacctgcacc ggcgcggcat
     8101 cgagaaggac ttcgtcaccg gcaacaacga cgccgacggt cccttcctgc tgcactgggt
     8161 gcaacggcgc ttccccgaca aggccgcgca catcgaggcc aagctgcgcc agtggggcgg
     8221 caacgcgagc ggggtgaatg tctccaacat cgacaacctc ggcatcgtgc acccggacac
     8281 catgtggtgg catgtgccgc tgggcaatgt gcgccagcgc gccttcggcg agatctggaa
     8341 cgacctctcc aacccgctgc tggccggact caagcagcat ccgcgcaagc tcgaagggcg
     8401 ctgcggggcg tgcaagtacc tggacatctg caacggcagc tcgcgcgtgc gcgccgagca
     8461 ggtcaccggc aacccgtggg cggaggaccc cgcctgctat cttctcgacg aggagatcgg
     8521 cgtgactccg gcggactacg gcgccgagcg cgtcgtcacc acgccttgga cccgcatcga
     8581 caaggtctcc gcatgaagcg ccacgccacg accctgagca gcgtgctcgc gctcgccggc
     8641 gcactctccg cagcgctcgt cgccctgcct gcatccgcct ctgcggagaa ggcggccgcg
     8701 ggggcggcct ccgccgcagc tgtttcgccc gcggccatcg acgtacccgc gctctacgcg
     8761 cagcactgcg cggcctgcca tgcgcccaac cgcctcggcg cgatggggcc cgcgctgctg
     8821 cccgacaacc tcgggcgcct gcgcaagagc gaggcggcca aggtgatcgc cgagggccgc
     8881 gcggcgaccc agatggccgg gttcgccgcg cagatgagca aggaagagat cgccgcgctc
     8941 accgaatgga tctacagccc ggtggtgccc gcgccgcgct ggaccgacga cgacatccgc
     9001 gcctcgcgca tcgtccacgt cgaccccgcg acgctctcgg acaagccggt cttcgacgcc
     9061 gacccgatga atctcttcct ggtggtggag gcgggcgacc atcacgtcag cgtgctcgac
     9121 ggcgacaagc tcgagccgat cttccgcttc cagtcgcgct tcgccctgca cggcgggccc
     9181 aagttcgccg ccgaggggcg ctacgtgttc ttcgcctcgc gcgacggctg gatcaccaag
     9241 ttcgacctgt ggaacctgaa ggtcgtggcc gaggtgcgcg ccggcatcaa cacgcgcaac
     9301 gtcgccgcct cgcccgatgg cacccacgtc gcggtggcca actatctgcc caacaccctg
     9361 gtgctgctcg acggcgatct caatctggtg aagaccatcg aggccaagga ccgcgacggc
     9421 aagaagagct cgcgggtctc ggcggtgtac gacgccaccc cgcgccagtc cttcatcgcc
     9481 gcgctcaagg acgtcggcga ggtgtgggag atcagctaca ccaaggcggt cgaggacatc
     9541 ccggtcagct acatccacga ctacacccag cgcgaaggga ccttcatccc cggctacctc
     9601 aatccgcgcc gcaccatcct cgccgaggtg ctcgacgact tcttcttcac ccaggactac
     9661 tccgagctca tgggcgcctc gcgcgagggc gtcggtcagg tggtgaacct cgacgtgcgc
     9721 aagaagatcg ccgacctgcc gctcgacggc atgccgcacc tgggctcggg catcacctgg
     9781 gaatggaagg accccgccgc cgggccggac gccaagccgc gtacggtgat ggcgagcacc
     9841 aacctcaagg ccggcgaggt caccgtgatc gacatgaaga cctgggaggt cgtcaagcgc
     9901 atccccacgc gcggcccggg cttcttcctg cgcagccacg gcaacagccg ctacgccttc
     9961 gtcgactcga tgatgagccc ggaggccaag cacatcctgc aggtcatcga caagcacacg
    10021 ctcgaggtgg tgaaggagat caccggggag cccggcaaga cgctcgccca catcgagttc
    10081 acccgcgacg gccgccatgc gctcgccagc ctgtgggagg acgagggcgc ggtgatcgtg
    10141 ctcgacgcgc agaccctgga agaggtcaag cgcctgccca tgcgcaagcc cgtgggcaag
    10201 tacaacgtct ggaacaagat cacgcgcgag gaaggcacca gccactgatt ccttgcggcc
    10261 gggcaggcgt ccggccgtgc gcagcttcac ccgtcttcaa ccccttcagc acaaaagaga
    10321 accgaacatg gcgctgatcc gcctcgacga accgaccacc aaacgcattc cgcccgacac
    10381 cttctcgctg tgggcgctcg ccttccgtcc cttctacctg ctcgcggcgc tgttcgccgc
    10441 gattgccgtg ccggtgtggg cggtggccta ctccggtgcg atcgagctgc cgatgccggg
    10501 catctggtgg catgcgcacg agatgatctt cggcttcgcg atcgcggtga tcatcggctt
    10561 cctgtttacc gcggggcgca actggaccgg gctcgacacg cccacggaca agccgctgat
    10621 ggtgctcgcc gcggtctggc ttgccggccg cctggcgatg gccttcggca gcggcgcctg
    10681 ggtggcgatc gtggacctcg ccttcctgcc ggtggccgcg gggatgctgc tcaaggtgct
    10741 gatcaaggcc aagagcaagc gcaactactt cgtcggcgcg ctgcccgcca tgctggcgct
    10801 cgcgaacctg ttcttccacc tcgccgtgct cggcgtcatc gaggccgacc cgctgaccgc
    10861 gatgcacctg gccctcggcc tggtggtggt gctcgagacc atcgtcggcg gtcgcgtcat
    10921 cccgatgttc accttcaacg cggtgcgcgg cgtcaagcag tggcgcaacg tgaagctcga
    10981 ctgggcggcg gcgatcgcca ccggcatcgc gctgctgctg tgggcgctcg gcgccggcgc
    11041 ctgggcgggc gtggtgtcgt tggtcgcggc ggcgctgcag gcggtgcggc tcggcggctg
    11101 gaacccgtgg gcgacgcgca gccagcccat cctgtgggtg ctgcagctgg cctacctgtg
    11161 gattccgctc ggcctcgcgc tggtcgcgct gacgcagttc ggcgtgctgc cgcgctcggc
    11221 cggcatccat gcgctggcca tcggcgccac gggtgggctg atcatcggca tgatcacccg
    11281 caccgcgctc ggccacaccg gccgcatgct gaccgccggg cgcatcgaga ccgccgccta
    11341 cgcgctggtg ctgctggccg cgctggtgcg ggtgctgacc gtggccttca tccccgctgc
    11401 gcagttgggc ggcgtgcatg ccgcggcgac gctgtggtcg atcgcgttcc tgctctacct
    11461 gtggcgctac gccccctacc tctggtatgc ccgcgtggac ggaaaggaag gctgaacgcc
    11521 tgatctggcg gagcggtgag cgcgtcgacg atgcggaggg tcgcgacgat gttcgccgct
    11581 ccgggggtct cttcgccggc gcacccttgc ggacgccgcg cgctccgtga tcgcgatcgc
    11641 gtgtcgtcgc cggagacttt ttcgccctag cgcggaaggg tcatggtaaa gcgagtgagg
    11701 ccttccgcgg atcgcgcggc gatctctccc ccgtgcgcgc gcacgatgga gcgcgtgatc
    11761 gcgagtccga gtccggcgcc ttcgcctcga gtctcgcgct gggcgctggc gcgatggaag
    11821 cgctcgaaga tgcgctcgat ctggtcggcg gggatggggg cgccgggatt gcagacgacg
    11881 aggcggatgg cggtggtgtc cgcctcgatc gcgatcgtga tccgctcgcc gtccggcgtg
    11941 tgccgcagcg cgttggagat caggttcgac aaggcgcgcc gcagcatcag gcggtccccg
    12001 tgcacgctcg cccgcccctg gcgcaggatg cggacccggc gttcctcggc cagcgcttcg
    12061 tagaaatcga tcagcgcatc gacctcgctc gccaggtcga cgacctcgcc ggcatgcgcg
    12121 agcgtgttct cctcggcctt ggcgagaaac agcatgtcgc ccagcgtgcg cgcgatgcgc
    12181 tcgtactcct ccaggttcga ggcgaggatg tcctgatact cggcgctcgt gcgcggccgc
    12241 gacagcgcca cctgggtctg cgtcatcagg ttggagatcg gcgtgcgcag ctcgtgggcg
    12301 atgtccgccg aatagtccga caggcgctgg aaggcggtct cgaggcgggc gagcatgccg
    12361 ttgagcgcct cgacgtggtc gcgcacctcg gcgggcgcgt cgcgcgcatc caggcgctcg
    12421 ccgagacgct cggcggagag ctcgcgcgcg gtctcggtga cccggcgcag cggcgccagc
    12481 ccgcgatgcg ctgcgaacca gccgaacacc gccgcgacca gcgcggcgag cgccacgccc
    12541 gcccaggtcg cacgctgcgc cgaggcgagg aagtgggtgt gatgggagag gtcgagggcg
    12601 acgaggatct ccagctgggg ctggaggccg ccgtccgccg cggctgcggc cgccgggagc
    12661 gcgaccgtcc cccgcagccc gaggtagggg tggccgtcga cctcccagcc tggctcctcg
    12721 ctcgtcaccg cctgccccgc acgctgcgcc gcgctgaagt gcgccggatg gatcagccgc
    12781 agcacgcgcc cgtcggcgtc gcgcacgcgc acgcccacgt tgtcgtggcc gacgagcgcg
    12841 gcctccaccg catccaggcg cgcctgcagc ggcgtggcgt ggtccacctg ctgcagcgtg
    12901 ttgcggatca gcacgagctt gccgtgcagc tcgtgcaggt cgagctcgtg gaagtgcgcg
    12961 tcgagcatgc gcccgtgcag cagcgcggcc agcaccagca gggtcgcggt gagcgcggcg
    13021 aacagcgccg ccaggcgcgc ggtcagcgag ataccgtggc tcatcgcggc gcgggctcgg
    13081 cggcctcgag cacgtagccc atgccgcgca ccgtgcggat cagcttgggc tcgaaggcgt
    13141 cgtccacctt ggcgcgcagc cggcgcacgg cgacctcgat cacgttggtg tcgctgtcga
    13201 agttcatgtc ccacacctgc gaggcgatca gcgagcgcgg cagcacctcg ccctggcggc
    13261 gcagcagcag ctcgagcagg gcgaactcct tggcggtgag gtcgatgcgc tgcccgccgc
    13321 gcgtcacccg gcggcgcagc agatcgagct cgaggtcggc cgcgcgcagc acctcggcct
    13381 cggggctgcg cccgcgccgc agcagcgtgc gcacgcgcgc gagcagctcg gcgaaggcga
    13441 agggcttgac gaggtagtca tcggcgccca gctccagccc gcgcacgcgg tcctcgacct
    13501 ggtcgcgcgc ggtgaggaag agcaccggca tcgtgcgccc gctgcgccgc agcgtctgca
    13561 ggatgcccca gccgtcgagc gagggcagca tcacgtcgag caccagcaga tcgtgcccgc
    13621 cctcgagcgc caggtgcagg ccgtcgagcc cgtcgcgcgc gaggtcgacg acgaagccgg
    13681 cctcgctcag gccctggcgc aggtagtcgc cggtcttggc ctcgtcctcg acgatcagga
    13741 tcttcatgcg ggtgtttccg tggggtgagt ggattgggtg gagtgggttg ggggcgttga
    13801 ggcggttgat gccgttgagg tcgtcgattc cgctgatgcc agcgccgagt gccggtgcgg
    13861 aatgatcgcg cgggttccgt ctgcgcggat tttgcccgag ggcggtgggg agggtgttgg
    13921 attacggaaa tgtaatcggc gcgtcaggct ggtgtcgggg agcggcttcg atactggcgg
    13981 cgagttcccg ggcagcccgc ccggcccgac atcgagaggc tcgcgacatg aagaaaccgc
    14041 tccgttccgc cgtctgttgc gcgttcgccg cgctgtccgg ctttgccgcg ccggtgagcg
    14101 cgctcgcgca gggcggccat tccgcgcacc acggcacggc cgtcgccacg ccggccgcgg
    14161 ccgagctcgc cgagggcacg gtccggaaga tcgaccgcgc ggccggccgg atcaccatcg
    14221 cgcacggacc gatcgccgcg ctggagatgc cgccgatgac catgatgttc cgtgccaccg
    14281 atccggcgat gctcgaccag gtcaaggtcg gcgaccgcat ccgcttcgcc gccgcggagc
    14341 aggacggcgc gctggtggtg accaagctgg aagcggcgcg ctgatgtggc ggcaccggag
    14401 cgtaacgcgc gtcgcagctg caatgcccgt tcgcggctgc cgccgctcct acaggggcat
    14461 gtcggttcgt gtcgggcgtc ggggnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14581 nnnngccgcc gctcctacag gggcgtgtcg gttcgtgtcg ggcgtcgggg ggcggggaat
    14641 gcgtcgggtg cgtgccggtt catgtaggag cgccggcagg cgcgaagacg gccgcgccgt
    14701 aaccgaaagc gggcgtcgca gctgcgttgc ccattcgcgg ctgccgccgc tcctacaggg
    14761 gcatgtcggt tcgtgtcggg cgtcgggggg cggggaacgc gtcgggtgcg cgccgattca
    14821 tgtaggagcg ccggcaggcg cgaatgccgc cgcccccgat cgcgccgggg attcatgtag
    14881 gagcgccggc aggcgcgaat tgcggccttg ggtgaatgga tgacctctcg ctcatcatga
    14941 aaaacgatct ttcctccctt gcgcggaggt ccctgctgca cggggcctgc atgctcgcgc
    15001 tcgcaacggg ccccggcctc acggccgcgc tcgcgcagcc gcctggcgcc acgggcgagc
    15061 ttcttcctcg ccacaccggc gagcttcctc ccggctccac gggtgagctt cctcccggct
    15121 ccacgggcga gcttcctcct cgccacaccg gcgagcttcc tcccggctcc acgggcgagc
    15181 tttccccccg ctccaaggga gagccccccc tcggcgcgag cgcacgcagc ctgatcgacc
    15241 aggctcgccg gaccaatccc ggcttcgccg cggcgcgggc ggaggtggat gcggcgcgcg
    15301 agcgcgtgac gcccgccggg gcgctgcccg atccgcgctt cgagctcgag ctgatggacg
    15361 ccaccaacac catgagcggg cgctcggcct cgctgctgcc agggcgcgtg ggcgagacgc
    15421 gctaccgcat cgtccagccg ctgccgggct ggggcaagcg cgagctggcg gtgaaggccg
    15481 cgcaggcgca ggtgggccag gccgaggcga tgcgcgacgc cgcctgggtg gagctggccg
    15541 cgaggatcga ggcgctgtgg ctgcgctacc acgcggccga ccgcgagcgc ggcctcgccc
    15601 gtgatgcgct cgccctgctg cagggcctgg aggcgctcgg cctcgcccgc tacgagctcg
    15661 gcctgctgcc gcagcaggcg gtgctgcgca tgcagcgcga gatcaccgcg cagcgcctcg
    15721 cattggtcga catcgagcag cgccgccagg gcctggcggc gggcctcaac ggcctgctcg
    15781 ggcgcgcgca cgacgcgccg ctggcggccc cggccgatcc cgatccgctg cccgaacgcc
    15841 tggaggcggc cgcgctggtc gatgcgctgg cgagcgccaa ccccgaagtg caggtcgcgg
    15901 ccaacggcat cgaccgcgcc cgcgccgaac gcgaacgcac ctaccaggac cgcctgcccg
    15961 acttcgccgt cggtgtgacc aacaaccgtc ccgacgaagg caaggcgtcc tgggacgtga
    16021 tgttcgaggt gatgatcccg ctgcagcagt ccagccgccg cgcgcgcgag cgcgaggccg
    16081 agtacctgct gatggcggcc gaggcccggc gcgaggacgc ccgcgcccgc gccagcggcg
    16141 agctgggcgg cgccgcgtcg atgtacgcgc gcggtcgcga gaccctgcgc ctgctcgatc
    16201 acacgctgct gccgcaggcg caggccaccc gcgacgccag ccgtgcggcg ctcgccagcg
    16261 gcacggtcga cttcgacagc gtgatcgagg ccgagcgcca gctcatcgac atccgcgtgc
    16321 ggcgcctgca gaccgagctc gagacccgcc tggcgctggc cgagatcaag aaactgaccg
    16381 gggagttcaa gtgagccttg cgctgcgcat gacgacggtg gcggtcgcgc tggcgatcgc
    16441 ggggggcgcg ggctactggc tcgcgcgcgt gcagcacggg gcggcgcccg cgacgccggt
    16501 tgcggtcgct gccgccgcgc cggtggcggg agccgcggcc gaggcagccg gcgggggctc
    16561 cggcgaggat tccggcaggg gttcccgcgg cggctcgcgc gagggctccg gcgtgggccc
    16621 tgccgacgac tcccgcggcg gcgaacgcca gatcctctac taccgcaacc cgatgggcct
    16681 gcccgacacc tcgccggtgc cgaagaagga ctcgatgggc atggactacc tcccggtcta
    16741 cgccgacgac cggcccgacg accgcggcgc ggtggtggtc agcccggcgc gcatccagac
    16801 cctgggcgtc cgcaccgccg tggtcgagcg gcgcgcggtc gatgccacgg tgcgcgccag
    16861 cggccgcgtc gagatcgacg agcgccgcca ggtggtggtg gcgccgcgct tcgagggctg
    16921 gatcgagcgc ctgcaggtga acgccgtggg ggacgtggtg aagaagggcc agccgctgtt
    16981 caccgcctac agtcccgagc tgcagtccgc cggcgaggag ctgcgcatcg ccgagcgcct
    17041 ggcccgcgac agcgcggcgc acgacccgct ggcgagcgaa tcggcgcgcc gcctcgccga
    17101 ggcgacgcgc gcgcgcctgc gcaacctgca ggtcgccggc cagtccggcg cgcgccaggt
    17161 cttccatgcg ccggccagcg gcgtcgtgct cgacaagatg gcggtcgagg gcgggcgctt
    17221 catggcgggc gaggcgctgt tccgcatcgc cgacctgtcc agggtgtgga tcatcgccga
    17281 cctctacgag caggacctcg cccgcgtgca ggtcggccag ggcgcgcagg tcgtgctcga
    17341 cgcctggccg gggcgcagct ttgcggcgcg ggtgggctac ctgtacccga cgctggacac
    17401 cgccacgcgc agcacccgcg tgcgcctgga actggacaac gccgaaggcc tggtgcgccc
    17461 cgggatgttc gcgcaggtcg tgctcgcggt cggcgacgcc accccgaaga cggtggtgcc
    17521 agtctcggcg atcatcgacg acggcgagcg ccgcgtggtg ctgcgcgcgc tcggcgaggg
    17581 ccgcttcagg ccgcaggcgg tgaagctcgg cgagcgcggg cgcgagtggg ccgaggtgct
    17641 cgagggcgtg gaggagggcg agcgcgtggt cgtgtccgcc aacttcctga tcgactccga
    17701 gagccagctg aaggccgcgc tggccaacct gatggcgctc gaggccgatg ccgccgccag
    17761 cgccaacgcc gccgcgcccg ccgcgcgccc gcgctacgac accacgggca ggctggaggc
    17821 ggtcgatctc gagacgcgca gcctgaccct gagccatgcg cccatccccg agctgaggtg
    17881 gccgcgcatg accatggact tccagctcgc cgacccggcg ctggtgcagg gcgtcgcacc
    17941 gggcagcgcg gtgcgcttca gcttcgaggt gggcgagccg ggcgagtacg tcgtcacccg
    18001 catcgaggcc gcgcaggcgc agcccgacgc gggcggcgac gtcgacgcgg caggccgcgc
    18061 ggtgccgggc ggcgggagcg gcgccggcgc ccatggaggc cattgagatg gcgccctccg
    18121 aatcctccac ggccgccgcc gtcccgcccg cgccgcctgc cggcgccgcc acccccggcg
    18181 ccgccaaccc cagcgtagcc agccccggcg cgctcgaccg cctgatcgac tggtcggcgc
    18241 gcaacgtctt cctggtgctg ctcgctacgc tcttcctcgt cgccggcggc ctctacgcgg
    18301 tgcacaagac gccgctcgac gcgctgcccg acctctcgga cgtgcaggtc atcgtctaca
    18361 ccgacttccc cggccaggcg ccgcaggtgg tcgaggacca ggtcacctat ccgctcacca
    18421 cctcgatgct ggcggtgccg cgcgcgaagg tggtgcgcgg cttctcgatg ttcggcgcgt
    18481 cctacgtgta cgtgatcttc gaggacggca ccgacctcta ctgggcgcgc tcgcgcgtgc
    18541 tggagtacct gagcaccgcg gccagccgcc tgccgcaggg cgtggcgccg cagatcggcc
    18601 ccgacgccac cggcgtgggc tgggtgtacc agtacgcgct gctcggccgc gacatgagcc
    18661 tcgccgagac gcgcagcctg caggactggt acctgcgcta tccgctcagc caggcccatg
    18721 gcgtggccga ggtcgccagc atcggcggct tcgtgcgcga atatcaggtc agcgtcgatc
    18781 cgctgcgcct ggcgggctac ggcatcacgc tcgaccaggt cacccaggcg atccgcgcct
    18841 ccaaccgcga cgtcggcggc cgggtggtcg agctcgccga gaaggaatac atggtgcgcg
    18901 ggcgcggcta cctgcgcgga gtggaggaca tcgccggcat cgtgctgaag gccgagcgcg
    18961 gcaccccggt gcgggtgggc gacgtcgccc gcgtcgagct ggtgcccgcc gagcgccgcg
    19021 gcatcgccga actcaacggc gagggcgagg tcgcctcggg catcgtgatg gcgcgcttcg
    19081 gcgagaacgc gctcgaggtc atcggccaca tcaaggcccg gctcgccgag atcgcgcccg
    19141 gcctgcccgc gggcgccgag atcgtgccgg tgtacgaccg ctccgagctc atcgagcgcg
    19201 ccatcgccaa cctccagtgg accctgctcg aagagagcct gatcgtcgcc gcggtgtgcg
    19261 tggtcttcct gctccacgtg cgcagcgcgc tggtggcgat cgtgaccctg ccgctcggca
    19321 tcctgtttgc cttcatcgcc atgcgcgcgc tcgggctggg ctcgaacatc atgagcctgg
    19381 gcggcatcgc gatcgccatc ggcgccatgg tggacgcggc gatcgtgatg atcgagaacg
    19441 cccacaagcg cctcgagcgc ctgcccgcgg gcgccggcga gggcgcccgc gcggcggcga
    19501 tcgtgcacgc ctgcaaggag gtcggcccgg cgctgttctt ctcgctgctg gtgatcaccg
    19561 tgtccttcct gccggtgttc gtgctcgaag gccaggaggg gcgcctgttc tcgccgctcg
    19621 ccttcaccaa gaccttcgcc atggcgggcg cggcgctgct gtcggtgacc ctggtgccgg
    19681 tgctgatgct gttcttcgtg cgcgggcgca tcctgcccga ggcccgcaac ccggtgaacc
    19741 ggctgctgat cgcgctctac cgcccgctga tccgcggcgt gctgcgctgg cgctgggcga
    19801 cgctggcgct ggcggtcgcg gcgatggcgg cgaccgtcgt gcccgcgcgc cagctcggct
    19861 ccgagttcat gcccacgctc gacgagggca cgctgttcta catgccggcg gcgctgccgg
    19921 ggatgtcggt gaccgaggcc gggcggctgc tcgccaccac caaccgcatc ctcaagacct
    19981 tccccgaggt cgcgtccgtg tatggcaagg ccggccgcgc caacaccgcc accgacccgg
    20041 cgccgctgga gatgttcgag accgtcatca acctcaagcc caaggaccag tggcggccgg
    20101 gcatgacgac cgacggcctg atcgccgaga tggacgccgc gctgaagttt cccggcctgg
    20161 ccaactcgtg gaccatgccg atcaaggcgc gcatcgacat gctcagcacc ggcatccgca
    20221 ccccggtggg ggtgaaggtc ttcggcaagg acctggagac cctggagagg ctcgcccagg
    20281 ccgtcgaggc cgccgtgcgc aaggtgccgg gcgcgagcag cgcctacgcc gagcgcgtgg
    20341 ccggcggtta ctacatcgac atcgagccgc gccgcgacca gctcgcgcgc cacgggctca
    20401 gcatcgacat gctgcaggag gtcatcgcca ccgcgctcgg cggcgagacg gtgacgacca
    20461 cggtcgaggg cctggagcgc tacgccgtgt cggtgcgcta cgcgcgcggc ctgcgcgacg
    20521 acccggcgcg gctcgccacc gacgtcttcg tgccgacgat gaacggtccg atcccgctcg
    20581 gccagctcgc cgaggtcaag ctgacgcgcg gcgcgcccgc catccgcacc gagaacgcgc
    20641 tgctggccgc ctatgtgtat gtggacacgc gcgaggccga cctcggcgcc ttcgtcgagc
    20701 gcgcgcagcg cgcggtcgcg gcggaggtcg ccttcccgca gggctactac gccacctgga
    20761 gcggccagtt cgagaacatg gagcgcgcca aggagaagat gaagatcgtc gtgcccttca
    20821 cgctggcgct gatcttcgtg ctgctctacc tcaacttcgg ccgcctggcc gagacgctga
    20881 tcgtgatgct gtcggtgccc ttcgcgctgg tgggcggggt gtggctgatg tggtggctgg
    20941 gctaccagat gagcgtggcg gtggcggtcg gcttcatcgc gctcgccggc gtggcggccg
    21001 agaccggcgt gatcatgctg atctacctcg accaggcctg gcaggagatg cgtgcgcgct
    21061 gccgcgccga gggccgcgcg ccgggggtgg cggagctgca tcgcgcgatc atggagggcg
    21121 cggtcgagcg cgtccggccc aagatgatga ccgtggtcac catcatggcc ggcctgctcc
    21181 ccatcctgtg gggtagcggc accggcagcg aggtcatgag ccgcatcgcc gccccgatgg
    21241 tcggcggcat ggtgtcgtcg accgtgctga cgctggcggt gatcccggcg ctgtatgcgc
    21301 tggtgaagcg gcgcgagctg gggtgagggc agtgcgctcc attcacgcgc tcccgtcccg
    21361 cagccatgcc ggttcctggt gtgacgcagg tggcggagca cacggttcgg ccgtcggcgt
    21421 ggccggccag taccgaccgc cgcagggcac gccttgcggc gctcccgcgc gggcggtccg
    21481 tcacccgcgc ggggtcaagg cgacgctcat ccacgccgtc cccggcgact tctccaccac
    21541 gatccgctcc cccgcgagcc ggtaggtcag ctggcagcca agcctcgggt tggacaggac
    21601 cgccgggttg aagatcgcca cattgtcgcc ggcgggccgg cggacggact ggatgaggag
    21661 gccggggtgg ccctcgtgac gaatccgcgc cccgaccgat tggctgaagg cgtaatccgc
    21721 tggatgcagg agatccgggt actccccggt aaccccgcgg aaatccagca acgcggccgc
    21781 gcaggcgacc caatacaccg tacgttccgc gaccaccgcc tcgcgttcgt acccggcatc
    21841 gctcagcagg ccgtgatacc agtgatgggc cgattcgaag accgtggtct cgatcgtttc
    21901 cgatccgtac cagacgccat ggctgccatc cgagaagcgg ctcgcctgcc agtgccggaa
    21961 gggccagtcg atcgcgttga accaggcgga gtcctcgaag ggacggtcga tgaccggcgt
    22021 gtgcgagcga tacggcggcg gcttgaccgc gtcctctacc tgctgggcca gcgaccactc
    22081 ggccgggttg tcggtgaggt cgtcgaacaa gtcctgcgac tcgcgcaggg agacgatgtt
    22141 gcgtgcgacg tcgcggcgga ggtcggccag cgtcaggcgt gcaaagaggg agttcaccgg
    22201 acgccccgtt cagacgccgc gcgcgcgatc cagataactc cgcaccatca gcagcccggc
    22261 aaagccccat tccttgacga cctccaccgg gctgaggttg tcgaaggcct tgttgcgggt
    22321 gctcatccag cggtaggcga ggtcccggtt gtgcgggaaa agcaggcgca ggttcttgtg
    22381 gatgcccagc aagtggccga cgcgctcgta ctggtcgcgg ctggtgccga tggcttcgcc
    22441 cttgcggtag cgcgcaagcg ccgcgcggtt gctggcggcg atcccgagca gcgcggcctg
    22501 atcttcggtg ctcagcttcc agtggtcgag cagggtcatg accatcctgg ccagcgcgcc
    22561 acggtcttgt gatgtagtgg tttcgcgttc ggcgatggca cccatggcgc actcctcgtt
    22621 ttgcgtggtc ggtacgatga gtgtagcgat gcgttgcgaa aaaaacaaag attggaagaa
    22681 acgaaacgta gagcgagcgg ggggcaaggg tcggtgaggg ccggatgagg gccggatggg
    22741 gcagctcttt catccgactc ttccggcgct gcgccggaac ccgccgaacg ttcagggcag
    22801 gaagcggccg aggcggtcga gttcgcttgc gaggcgcgcc tgatcctggg cacccccggg
    22861 ctgcaacagc ggaagcaggc gttcgatgcg ggcgcgcagg atgtgataga cgtcgagcag
    22921 ctcgccgtct gcgcgccggg cgaagaggtg ccgctgcagc gggtcatgca ccgtccagcg
    22981 gacgtggagc ggcgcgtcgg cgcgatgcgg gcaggcgtgg tcggcgcgca tcgagcacag
    23041 ggaaatgagc acgtctcccg cgcgcaacgc cgcgctgggc gtttctgctg tggtcgggcc
    23101 gggccggatg ccctggcgct cgagcagcgc gagcgcggcc ggcgagggcg gctcgtcgcg
    23161 gtcgcaggcg acgcggcggg ccttgcagtg gcacggcgcc agatggttga agatggcctc
    23221 tgcgagcagc ggccggcagt ctccgccttt gcctacgaag agtatgtcca tgctgtcgga
    23281 ctcccggtcc ttgccagccg gtgtcgcttc cccgcccggg gggcgacgcg ctgaccccga
    23341 gagtgtccgc ttcgattgtt tcaatccggt gaaggctcca tgtgcctgtc acggagctgt
    23401 cacgctgccg taagacgatg gcggtgggcg ccgggtttgg cgcgtgatcg ggaaacgcac
    23461 atggacaatc gcgaaatcgc cgacctgcac cgcaggatcg agcgtgaact gctggacagc
    23521 tacgacgagg agctggagct cgagctcgac gaccagcgct tcgacgagat cggctcgggc
    23581 gaggccccgc ccgagagcgc ggacgagcgt gccaagcgcc ggcgctattt caccgagctg
    23641 ctgcgcctgc agggcgagct ggtgaagctg caggactggg tggccacgac ccggcatcgg
    23701 gtggtgattc tcttcgaggg ccgcgacgcg gcgggcaagg gcggggtcat caagcgcatc
    23761 acccagcgcc tcaacccgcg cgtgtgccgg gtggttgcgc tgcctgcgcc caacgaccgc
    23821 gagcgcacgc agtggtattt ccagcgctac gtgccgcatc ttccggcggc aggcgagatg
    23881 gtgctgttcg accgcagctg gtacaaccgc gccggcgtcg agcgcgtgat gggcttctgc
    23941 accgacgcgg agtacgagga gttcttccgc tccgtcccgg agttcgagcg catgctggtg
    24001 cgctccggga tccagctcat caagtactgg ttctcgatca ccgacgagga gcagcatttc
    24061 cgcttcatgt cgcgcatcca cgatccgctc aagcagtgga agctgagccc gatggacctc
    24121 gagtcgcggg cgcgctggga gcgctacacg gtcgccaagg agaccatgct cgagcgtacc
    24181 cacatccccg aggccccgtg gtggatcgtc gaggcgaacg acaagaaggc ggcgcggctg
    24241 aactgcatcc accatcttct cggccagatg ccctacaccg aggtgcagcg gccgctggtc
    24301 gagttgcccg cgcgcgtgcg caacgccgac tacacccgcc atccggttcc ggcggacatg
    24361 atcgtgccgg cgtggttccg ctgatttcct aggtctggcc ggttcgcatc ctggtgcgcg
    24421 cccggtctgg cgtcggcgtg gcaccgggcg cgtggtgatc cgcgcaggag aacccgtccg
    24481 tgcgcgtgac cgtggaggcc tgcgcgagga tcgcgtcgag gatgtccggg acctcgaaga
    24541 gcgcctggtt gtcgatgcgg cggacgctgg cctggaagtc ttcgaggcga tcgagcaggc
    24601 gggcgaccgc caggtcgatg gtgcggaaac cggtatgcac gacgccgagc ccgttttcgc
    24661 ggatccattc cgcgttgtag cgctcctggg gcatcgtcca cgcgttgtcg acgacgatca
    24721 ccggcagccc ctgctgcacg gcctcgctga tgctgcccgg gccgggcttg ccgatgaaga
    24781 agtcagcgag gcgcatgtag tagggaatgt cggaggtgaa ctcgaccacc aggcgcggcg
    24841 cggcgctggg gagcgcgcgc agcttcgccg ccagtgcctt gttgtgtccg cacaggaaga
    24901 tggtctgtgt cgtcgccgcc aggcgctgcg cgatgccgag catcgcgcgc gagccgtgtc
    24961 cgccgaacag gaccagcccg gtgggccgcc gggggtcgag gccgagccgc gcgcgttccg
    25021 cgctgcggtc gattgcgagc ggctcgtaga actcgggacg caggatcatg cccgaggtcg
    25081 catgcacgcg ttgcgtgttg tggccgagcg cgagcgcctg ctcgaccgcc cgcggcgtgc
    25141 cgcagatgaa gtgctggggc tgtccggcct cgatccagaa gttcggcggc aggtcggcca
    25201 ggtcggtgag cagggtcgcg tagggaacgc ccggcagggc acctgccagg ctctcgtaga
    25261 gcgcgcggtt gaagttcggg atcagcgaga cgaccaagtc cggctcggtg cgcagccagt
    25321 gttcctgcaa ggaccgcatc agcaaggggt ggccgagacg gatcgcggcc tggagcagct
    25381 tcagctcctg cgtcatgccc agggtccagc cgcgcgccag acgcttgttg taccagtcct
    25441 ccggccggct gccggtgagc gcgcgaaagc gttcctgagg gtcgaggacg gcgaagagat
    25501 cgaccgtgcg cacgcgccac gaaggcctct gccgctgcag ggcagcctcg agcgcgagcg
    25561 ccgaggcgcg gtggccgccg ccggcgttga agtagatcag atcgacggtc gtggtgctca
    25621 tggcgtgctc ccggctgcgg gcgcaggcgt ggtgtcggtc atcggggcca tcggtcgggc
    25681 gtcctggtcg tcaccgtcag cattgaagcc cagcgcatgc cggaggctgt cggcgaactc
    25741 ggccggggag gcgtggatga aggcgtccgg gacgccgtag gcgtcggtca ggcgctgccg
    25801 gtcctccgcg ccataggcga cgatgaaggg atacatgccc gcacccaggg cggcgaggta
    25861 atcgctgtac tcgtcgccgc acgcgtaaca gcgcgcgggg tggatgccga gccgatcgcg
    25921 ggcctggcgg aagtggggcg tcttgtcctc gcgcagggaa aggcaggcga ggtgatcgaa
    25981 ggcgtcgagg tcgatgtcgt ggcggcggaa gagctggcgc agggtttccg cgggctccac
    26041 ggtgacgttg cgcgtcacca ggcccacgcg cacttcgggg gcgtcgagca gctgttgcag
    26101 cagtggcgcg atgccagggt agagccgggc ttcgtcgcga tagaacccgg tcagcgtcgc
    26161 cagcagccgt ttgcggctct gcttgccgaa ctgcctgcgc aggttgttgg gaaactcgcg
    26221 cagcccgccg agatacttga acagtctgcg gcgcttctgg aagcgctgca gatcgccgat
    26281 cgccatgccg tggcgcagga agctctgctc gacggcatgg aaggcgtcga tggtcgttcc
    26341 atcggcgtcg aagatcacca gccggtcggg gttccgataa gcagtcatgc cggaaagcta
    26401 tctcagccgt gcgacggatt cgtgacggcg gcgtgacgta tcgcccgacg gtcgaacggc
    26461 cggcgccgcc aaggcacccc gatcgcaccc ggcatccgtt ccggtcgaga tcgtcgtctt
    26521 gtctggttcg ccagacggat cagcgagcgg gtctggcgtc aggccttgct cttctcgagc
    26581 agcccgtgct tgatggcgac gtgggtcggg aggttgaacc tggagggtag ctggcggcgt
    26641 ttgaaccagc cgtagcgcga gtgttcgcga ttcaggcgcg gggcgagttc gcgctcgacc
    26701 tcgagcagga aatagtgcag ttcgcgatca tcggcatcgc gatggcggat ggtcgagatc
    26761 cgcctcagtg ccttgcgctt gatccgcagc ccggcctcct ccgcgagctc tcgtgtcagc
    26821 gcccgggcag gcgcctcgcc acggtcgacc cggccgccga acaggttcca ggcgccaccg
    26881 ttattgacgg cctgggagcg tttaccgagg agataggtgt ccgtcttcgt gcaatgaatc
    26941 actgcccaga cacccggggg cggtgtggag gagagacgtt ccttggccat gttcgcgaga
    27001 ggatcgttat ggattcgagc gggagacggt caggcaacaa tataaagcgt ttatataata
    27061 taaatatggc gaatttattt cagctacttg acgaaggatg agctgtccat gcgggctgct
    27121 agtggcgcag cagaaacacc ccggccatga cgatggtgcc tgcgaggatt ccgctctgga
    27181 gccgaccctc cttgaaccag agcgcgccga tcagcaccgc aaagatgacc gaactttcgc
    27241 gcagcgccgc caccacggcg accggggccc gcgtcatcgc ccagagcacc gtggcgtagg
    27301 cgagcatggc cgccatcgct ccgacgagcc cgagccgcca gtggtcgagg gagtagcggc
    27361 gcagcgcgct ggcgtcgcgg cgcaagcccg cgagcaggac gccgatcggt tcgagcaggc
    27421 tgaggaagaa cacataggcc agcgggttgc ccgcgaggcg cgcaccctgg ccgtcgacca
    27481 gcgtgtaggt ggagatggcc agcgcgttca gcactgcggc gtgggtggac gggtgcgtgg
    27541 cgatgcgggc gagtgtcagg ccggaagcga agccgatgcc gatcaccccg cagctgatca
    27601 aggcgatgcc ggcagcgcct tccggaccga gcgcctcgcc gagcacgggg ccggagagca
    27661 ggccgacgat cagcggtggc aggccgcgca tcagggtgta gctggtggcg agctgcccgc
    27721 cctcgtaggc cctgatgagc agcatgatgt aggcgctgtg gatgacggcc gagagcgcca
    27781 ggtagggcca gctcgcgggc gcgggcaggc cggtgaagag caggcccgct gctccgagcg
    27841 ccgcgctgaa ggcatgcagc agcagcgtgt agaggcgttt gtcgcccgcg ccccggatga
    27901 gcgcattcca gctcgcgtgc agcagggcgg ccgcgaggac ggcgagggcg atgcccggcg
    27961 tcagccccat gtcaggcccg ggactcggcg tccagggctg cgacgatgcg ctcgagcgcc
    28021 caccacaggt cggcctcgtc gatgttcagc gggggcgcca gcaccaggac cttgccctgg
    28081 ccgaccttga aggagatccc gtccgacagg cagcggtaca gcacggcttc cgcgaggtcc
    28141 tgtgcgccgc gggtggccgt gtccctcagc tcgatcccga tcagcaggcc ggccgagcgt
    28201 atcgaggcga cggcctggtt cttggcgcgt tcgaggtaag ccatgacggc ctcgccgagg
    28261 cgcaggctgc gcgccagcag ttgctcttcc tcgatgacgt cgagcaccgc gagtcccgcc
    28321 gcacaggcga gcgggttctt ctcgtgggtg tagtgtccga gcgagatgtg ctggccgaca
    28381 tcgaagcgcg accttgcgat cagggccgcc agcggcatcg atccgccacc gagtcccttg
    28441 ccgatgacga ccatgtccgg ctcgatgccg tagcgttcga ttgcaaagag atgcccggtg
    28501 cgaccgagtg cgatcggaat ctcgtcgaga atcagcaggg cgccgtggcg gtcgcagatc
    28561 cggcgcaggc gacggtagta gtcgggcggt ggaatctgca cgtcggtgca gcggatcgtc
    28621 tccaccacga cggcggcgac gtcgccctcc ttgcgcaggc aatagtcgat gtagtcgaca
    28681 cagcgcaggg cgcaggtgcc gccgcagccg aagacgcatt ccgccgggtc gcagggagga
    28741 acgtgctcgg tgccggggag cagggggccg ataccccggc ggaacacggc ctcgccgccg
    28801 agcgagatgg cgtcgagcga ggcgccgtgg aatgcgtccc acatcgacag ggtcttgaag
    28861 cggccggtga ccaggcgcgc gagcttgagc gccatgccga tggcggccgt gccgcccggg
    28921 gcgaacagga gcttcgcctc ctccatcggg gccgctatac acagtcggcg tgcgagctcg
    28981 atggcgtggc gattggtgta gcggcgcggg ctgaagggca gcgcttccag cgtctcgcgc
    29041 atggccgcca tcacccgcgg gtggccatgg ccgacctggt ggaggctgtt gccgtggaaa
    29101 tcgaggatgc ggcgccctgc ggtgtcggtc agccatgccc cctgcgcggc ttcgaggacg
    29161 ttgaggcagg gggtgctcat cgactggtgc aggaaccagc gcgcgtcctc gtccagcaat
    29221 gcgcgggtct cgccgtcgat atgcgtcgac tgccacgccg tccggcgatc gctgagattg
    29281 acgtcgcctt cggatcggtc gaactcagcg cgcatggtgg gcttccgtgt aggcgccgtc
    29341 gcgcagcatg cgctggcgcc cgccttgggc gtgggtgagg agggcctgcg cgcagcgttc
    29401 gccatctccg ctggccagca gatcgacgat cgcgctgtgt tcgtcggcga aatgggggat
    29461 cgccatcggt gcgaacaggt tgcggcggcg gaagagggtg agttgcttga cgagcttgcg
    29521 atagatgtcg agcagggaac ggttgccggt catctccacg atctggtcgt gaaaccgcag
    29581 attgagcaca tggaacccgt cgatgtcctc ggtggccgca gccgcctgca tgcggtcggt
    29641 catgctccgc agcgccgcga gctgtaccgg ggtgatccgg ctcgccagca gccggccggc
    29701 catcgcatcg aggccggccc gcacctcgta gatgtcggcg gcctcgtcga gcgcgatctc
    29761 gcgcacgaag gcgccccggt tcttctcctg gcggatcagc ccggactcct cgagcatccg
    29821 gaacgcctcg cgcagcggac cgcgcgagac gccgaggcgc tcggccagcg ccacttcgtt
    29881 gagcttggca ccgggcgcga gctcgcccga gaggatcgat ttttcgaccg actcggcaac
    29941 cagtcgggtg agcgaggtgc tctgcaccag ggtcagggcg gtgtcggtcg ggtcggtgag
    30001 cagggcgggc atttcgagcg gcaggagacg ggttggaatc ggcagtgtag ctgattttcc
    30061 gttttgtaga ttgtcaacaa tctgcaatct gccccctcta agctgttggc agtctagtcc
    30121 ggctccttga ccttcgcgtg acaggagcag gcccggcatc cgcttcgccc ctttcctccc
    30181 ggagaccccg catgacgctg aaacgcctcg cccaaagcct cgccgccctt ggcctcgccc
    30241 tctcggtggc gctgcccgcc cacgccgaca agtcggtgct caacgtctat accgcgctcg
    30301 agaccgacca gttgaaggcc tatcaggaag ccttcaacaa gcagtatccc gacatcgaga
    30361 tcaagtggac ccgcgactcg accggcatca tcaccgccaa gctgctcgcc gagaagggca
    30421 agccggtggc cgacgtcatc atgggggtcg ccgcctcgag catggtggtg ttcgaccgcg
    30481 agaacatgct gcagccctac gcgccgcaga acctgaagga gatcaacccg aagttccgcg
    30541 atgcggccaa cccgccgaaa tgggtgggca tggacgtatg gggtgcggcc gtctgctaca
    30601 acgtggccga gatgcagaag cagggcctgc cgcgcatcga gagctggaag gatctgctca
    30661 agcccgagtt caagggcaag gtggtgatgc ccaacccgaa ctcgtcgggt accggctttc
    30721 tcgacgtgac cgcctggctg cagatgttcg gcgagaaggg cggttgggaa tacatggaca
    30781 agctgcacga caacgtcgcc gtgtatacgc actcgggctc caagccctgc gtgatggcgg
    30841 gggcggggga gtttccggtc ggcatctcct tcgagtaccg cgccaacacc gtgcgcgaga
    30901 agggcgcgcc gatcgacgtg atcttcccga gcgaaggcct gggctgggac gtcgaggcga
    30961 tcgcgatcgt cagggacacc ccgcgcctcg aggcggcccg caagctcgcc gactgggcgt
    31021 cgacccgcga ggccaacgag ctctacgcga agaacttcgc cgtggtcgcc atcccgggga
    31081 tcgccacccg cctcaagcac gttcccaatg actacgagca gcgcctggtg aagaacgact
    31141 tcgcctggat ggcgcagaac cgcgacgcga tcctcgccga gtggcagcag cgctacgcca
    31201 acaagtccga agcgaagaag taagacttcg gcgctcacgt tgccccggca ctcgtccggc
    31261 cggggcgacg ctcgtctttt ccgggatcac gcatggaaca cctcgaaatc cgcaacctga
    31321 ccaagcgctt cggcgccttc gtcgcgctcg accaggtcga tctggctgtc gctcgcgggg
    31381 agttcctcgt gctgctcgga ccgtccgggt gtggcaagac gacactcctg cgcgcgatcg
    31441 caggactgga gcggcaggat gccggcgaga tcttccatgg gggcgacgag atctcgcagc
    31501 gatcccccgc gctgcgtgat ttcggcatcg tcttccagtc ctatgcgctg tttccgaacc
    31561 tgaccgtcgc cgacaacgtg gcctacggac tgaagagccg caaggccgat cggggtgtgg
    31621 gccgggacgg tgtgcgccgg cgcgtcgccg agatgctcga tctggtcggc ctgcccggca
    31681 tcgagcacaa gtacccggcg cagctttcgg gtggccagca acagcgtgtc gcgctggcgc
    31741 gtgcgctggc gacggcgccc gacctgctgc tgctcgacga gcccctgtct gcgctcgatg
    31801 cgatcgaacg cgtacggctg cgatccgagg ttcgccagtt gcagacccag ttgggcgtga
    31861 ccacgatcat ggtgacgcac gaccaggaag aggcgctggc gatggccgat cgcatcgtgg
    31921 tgatgaagag cggtcgcatc cagcaggtcg gcgctccccg ggacatctac cgcgcaccgg
    31981 ccaacgactt cgtcgccgac ttcatcgggc gcggcaacct gatcgagggc gcagccgccg
    32041 gggcgcgcca tgtccgcatg cggaatctga ccctgcgttg tgccgagccc ttggcgcccg
    32101 gtcgctcgca ccggttctac gtgcgccccg aggacatctg cctgtacgac accctcgatc
    32161 ggtgcgagaa cagcttctac gcgcaggtgc agaagcatga attcctcggt gcctactcgc
    32221 tggtgacctt gcatgcgcac gacctggcgg agcagccgct ggtggcgcag ttctccagca
    32281 actacctggc gggacggccg atcgcagcgg gggccacgct gcgcatcggc atcccgcccg
    32341 agcatctgcg cccgatgccg gagccggcat gacacgactc gcatggtcgc tcccacggct
    32401 cggcgagggc cggtcgacga gcgagcgcct cggcaccggc ttgctggtgg gcgccgcgct
    32461 gctgctgtgc gccttcctga tcctgccgct cggggtgctg ctgttgggga gcctgttcga
    32521 cgaagcgggc gagctcagcc ttgtgcgctt tgccgaattc gcctcgacac ccgggatggg
    32581 ccgtgcggtc tggaacacga tctgggtcgc ggtggtggtc acggtgctca ccgtgccgct
    32641 ggccttcctc tacgcctacg ccatccagcg cgcctgcctg ccgctgcgcg gggtgtggcg
    32701 gatcgtcggg ctctcggcct tgctcgggcc ctcgctggtc ggcgcgatct ccttcatcca
    32761 gtggttcggc acccaggggg tgctcaagag ctggctgggc gagcactcgg tgtacggacc
    32821 gatcggcatc atcatctcga cggtctatgc gagcttcccg catgcattga tgatcctggt
    32881 cgtggccctt gccaccgccg atgcgcgcct gttcgaggcc gccgaggcgc tgtcggcctc
    32941 gcgctggcgc aagttcgtca ccgtgacgct gccgagtgcg cgctacgggc tgatcagcgc
    33001 ggcgctggtg gtgttctcgt actcggtcag cgagttcggc atccccaagg tgatcggcgg
    33061 caatttcccg gtgctcgcgg tcgaggtcta tgtgcaggtc gtcggcatgc acaacttcgg
    33121 tcggggcgcg gtggtcgcct tgctgctgct gtttccggtg ctgctggcct ttctcgtcga
    33181 ctggcgcatc cagcgcaagc agcaggccag cctcaccgcg cgcgccgtgc cctatgtgcc
    33241 gcgccccgac tggcggcggg atctgcccct gcttgcctac tgcgtgctgg tgagcgtggc
    33301 gatgctgggc gtgctgggca tggcggccta cacatccttg gtcaagttct ggccgtacaa
    33361 cctcgaactc tcactcaccc attaccgcta cggcctggcc gaggcgggcg tgctcgatgc
    33421 ctacctcaac agcttgaaga tcgccggcct gaccacgctg gtcggcacgc ccttcatctt
    33481 cctggtggcc tatctggtgg agaagaaccg ctccggcccg gcgtggctgc gcccgctggt
    33541 ccagggtgcg gcggcgctgc cgatgggcgt gccggggctg gtgctgggca tcggctacat
    33601 cctgttcttc aaccacccgt cgaacccctt gaacggcctc taccacacgt tggcgatcat
    33661 ggtgatcgcc aacgtggtgc attaatacac ctcctgccac ctcacggcgc tgacctcgct
    33721 gaagagcatc gaccgcgagt tcgaggcggt gtcggcctcg ctgaaggtgt cgcagttcgt
    33781 gaccctgtgg cgggtgacgc tgccggtgtg cctgccggcc gtgctcgaga tcgcgcgcta
    33841 cctcttcatc aacgcgatga ccaccgtgtc cgcgctggtc ttcctgtact cgcccgagac
    33901 cctgccagcc tcggtctcga tcctgaacct ggacgaggcg ggcgagctcg ggccggccgc
    33961 cgcgatggcc acgctgatcg tgctcacctg tgcgctggtc agcctcctgt attcgctgct
    34021 cacgcacttc ctgttccgtc gccagcaggc gtggcggaac ccgaaccgat aggaacccgg
    34081 agaatccatg tactcgaccg atcgcgatcc cctgctgctg acccccgggc cgctgacgac
    34141 ctcgctgcgt accaagcagg ccatgctgca cgactggggc tcatgggatg ccgccttcaa
    34201 ccgcgtcacc ggcgagctgt gccggcagct cgtggacatc gtccatggcg ccgacacgca
    34261 cgtctgcgtg cccctgcaag gctcgggcac cttctcggtc gaggccgcgc tggggaccct
    34321 ggtgccccgc cacggcaagg tgctggtgcc caacaacggc gcgtattgcg cgcgcatcgt
    34381 ccgcatcctc ggctacctgg gccgcgaggc ggtcgaactg ccatttcccg aggattgtcc
    34441 ggccgaccct gcagccatcg aggcggcctt gctcgccgac ccggcgatca cgcacgtggc
    34501 gcaggtgcat tgcgagaccg ggaccggcat cctcaatccc ctcgccggga tcgccgccgt
    34561 ggtcgcacgc caggggcgcg gcctgatcgt cgatgcgatg agctccttcg gcgccatcga
    34621 catcgatctg cgttcgctcg cgatcgatgc ggtggtcgcg gcctcgggca agtgcctcga
    34681 gggcgtcccc ggcatgggct tcgtgatcgt gcgccgggct gcgctggagg ccgctgcggg
    34741 gaactgccat tcgctggcgc tggacctgca cgaccagtgg gcctacatgc agaagaccac
    34801 ccagtggcgc ttcacgccgc ccacccacgt ggtggccgcg ttgcacgagg cgctcgccca
    34861 gtaccgcgag gagggcgggc tggccgtgcg cggggcacgc tacgcgcgca actgcgtcgc
    34921 gctgatcgag ggcatgcgcg ggctgggcct gcgacccttc ctcgcccccg aagtgcaggc
    34981 gccgatcatc gtcaccttcc atgcgcccgc acatccggcc tacgacttca aggcgttcta
    35041 cgagcgggtg cgcgagcgcg gcttcatcct ctatccaggc aagctgaccc gggtcgagac
    35101 cttccgcgtg ggctgcatcg gcgcgctggg tggcgcagac atcgagaagg tggtggcggc
    35161 ggtcggcgag acgctgcgcg aagcgggcat cgtgctgggg gcaggatgag tgccgacctg
    35221 gaccgcgcgc gcgacatcct gatcatcggc gccggcatct tcggtgcggc catcgcctgg
    35281 tcgctcgccc gccaggggca ggggcatcgg gtgacgattc tggagcgtgg acaccctgca
    35341 ggcggagcga ccagtcgagc ggcggcgctg gtgacgcaga tccgcgacga cccggtgctc
    35401 gtcgcgctcg cccgggaaac cttcctcgcc atgcaggcgc tcgaggcgga aggcgagcat
    35461 ctcgggcgtc accacgccgg tgcgcttcat gtagtgtccc ggcagggggc cgaggccttg
    35521 tcgcagcgcg ccgaggccgc agccgccctc gggatccgca gcgagcgacc gagccgtgcc
    35581 gaggtgcagg cgcgtgcgcc ctggttgcga cggcaggccg gcgactgcgc cgtgttcttc
    35641 ccggaggact gctacgtcga cccctacctg ctcgcctcgg cctacctgaa ggctggcgtt
    35701 cgcggcgggg tgcgcttgat gcgggacgcc gacgtccgcc acgtgctgca tgccgacgcg
    35761 cgggtgaccg gggtcgagtt gagcgacggg cggcgccttg aagcgcgcgt cgtcatcaat
    35821 gcggccggtg cctgggcgaa cctgctcagc gtcgaactgg gccttcccct gccgatggcg
    35881 cccgtgcgca gccactactg gatcaccgag caagcgccga tctttccgcg caatggcgcg
    35941 atcgtgttca tgcccgagat ccgcgcctac gcccgccccg aagtcggcgg cctcctgttc
    36001 ggcatccgcg agcgctcccc cgcggtggtc gatgcgcgca agcttccggc ggacctgagc
    36061 ggattcgtgt tcgatccggc cgatgcggat ggctgggaga gcctggccga gggggccgat
    36121 ccgctcgagg gtttcttccc cgcagtgcgg tcgctccgca tcgcgcatta cgtgaccggg
    36181 ccgagcaact acaccgatga cgctcagctc atcctcggcg cctcgcgccg catcgatggg
    36241 ctgttcgtcg cctccggctg taacggctcg gggatcacct tctccggcgg tgtcggcagg
    36301 ctcctcgcgg aactcgtcct gcacgtgtcg ccgttcatct cgtccgcgcg cttcgacccg
    36361 gcgcggcatg cccccttcga cccctatgcg cccgcattcc tcgcccgctg tgcggcgacg
    36421 cgcgcgggca aggcgtccgg gtgagcgatc accacttccc aagacaggaa tacaccacca
    36481 tgcagcatcg actcgaagca gtgatcttcg attgggccgg cacgaccgtc gatttcggct
    36541 ccttcgctcc cacccagatc ttcgtggacg ccttcaggca ggccttcgat ttcgagcttt
    36601 cgctcgccga ggcacgcggg ccgatgggcc tcggcaagtg gcagcacatc gaagcgctcg
    36661 gtgcggaccc cgtcgtcggc gcgcgctggc aggcccgctt cggccgcccg atgagccatg
    36721 ccgacatcga ccacatctac cggacctttc tacccttgca ggtcgagcgc gtcgccgccc
    36781 acgcggacct gatccccggg acgctggaga cgattgcggc gattcgtggg cggggcatga
    36841 agatcggctc cacgaccggc taccctcgcc aggtgatgga gcggctgatg gcagcggcgg
    36901 aggcgaaggg ctatgccccc gactgcaccg tatgcgccga cgatctcgag gcgggggccc
    36961 gccccggccc gtggatggcc ctgcagtgcg tgctggatct cggcatcggc agcgtggccc
    37021 gctgtgtgaa ggtggacgac acgctgcccg ggatcgcgga ggggatccat gcggggatgt
    37081 ggaccgtcgg cctggcgctc tcgggcagcc cggcgggctt gacgctggcc gagtacgaga
    37141 cggcatcggc cgaggaacgc cgcgcggtgc gcgagcgcgt caccccggcc ttcgtcgaag
    37201 ccggcgctca tttcgtcatc gacacgatcg ccgaactggt cccggtgctg gacgagatcg
    37261 aggcgcggct tggaagaggg gagcgcccgt gaagtgctca cccgcctgag tgcagcgctt
    37321 cgatccacgt cgtcggggca gccgggggct acgatgccca cggcatggct ccgcccatcc
    37381 aggtgtcagc cggcctagac cttgtgtcgc tcccgcagct tggccatgtt ccggtgccat
    37441 tccgtcagcg cgtcgccgtc gtcgatcaga tctgcgatgc gcggcttcgg gagtgcgcgc
    37501 gccccctggt agtggagcgt tgatcggtgc gcgtcgcccg tgatgaagcg gtgcgagttt
    37561 gcggcggcct ggtcgagcgg atcaagtgtg cgctgcatgt gtatccctcc tgtcaattgc
    37621 tctggaaact cccgcatcgg tcgcttgtgc gtctgcccga acacggcgga tggttcggct
    37681 cgcaggagat tctccgcccg aggatccgat cttccggtta cgtttttgtg acggtgccgg
    37741 ccccggtgcc gcagatgccc catttcagcg agccctggat gaccaggatc atcaggccgt
    37801 catccgcccc tgtcagagtg tgggtggtgg catggccagt tgccgtgctc cgcgatctgg
    37861 acgagcagcg cgccgatgag accgaatgca gacatgccgg ggcactccgg ccggatcccg
    37921 cagcgttcga gccccgtccg ctcgacaccg ctgcggctgc ccctgcacat tccggtggcc
    37981 gtgctgttct cgctgctgat cctcggggtg ggcgcgacga tctcgcttca tcatttccgc
    38041 gaaaccagcg cactcctcga ggcggcaaac cagcgtctgt tccgggcgct tgccgaagat
    38101 gtccgtgcgg ccctcgagga cgtcgagcgt tcggttcgac gcgcattcat cctgctctcg
    38161 acctcgccgc tcgcggacgc ggcgggcttc gcagaacgcc tccggttcct gccggagctc
    38221 accggactca tggcggccga cccgctgatc gactcggtca tggtcgggta cggcgacggc
    38281 ggcttcttcc ttctgacccg cgccagcgca agccagacag ggcggggtga ggcggtgtgg
    38341 acgctgctcg acgccggcag gtccgagcag cacgacgctc cgccagtgcc gctcgagtac
    38401 cgcttcgacc gggacctgcg tttcctcggc tcctcaccgg cgtcggcggc accctccgag
    38461 ccgcgcctga ccgactggta tcgccgcgcg gcggcgagca acgcgctgat cgtgtcgcca
    38521 ccctacgcat tgcggcactc gggctcgcgc ggactcactt tcgcccagcg caacggtgcg
    38581 gccgtggtcg gtatcaacgt cgattttgcc gcactgtccc tggcgatgtc ccgggagtcg
    38641 gccataccct cgacgctggt gcgccttctg gcgagggacc gcagcgtcat cgcgggacac
    38701 actgcgccgg ctggcgcagg ggctccggag ggtgacgtcc tgattacccg agccctggac
    38761 gcgcccgcgg gcgatgggtc atcgacacgc gtcctcgagg atgcggccgg acggagctgg
    38821 cacgtttcgt tggcgccgct cgccggtctc ggcgacgacg gctggaccct ggccgtggcc
    38881 gtcccggacg atgagatctt cgccgaggcc ctccgccagc gcgagcgctc gattctcttc
    38941 acgatcgtcg ccgtgctgct cagccttccg ctcgcatggg gcctgtcccg cctgctgacg
    39001 aaacccctgc accgactgtc gggcgtggcg catgcggtct cggcgttgca gttccgctcc
    39061 ggggcggaaa cccactcgat catcctggag gtcgaccgcc tggcgggggc gatcgcgatg
    39121 atgcaggcca cgatcgcgcg cttcatcgag ctggggcgcg acctcggcac ggcccgggat
    39181 gtgcgcagcc tcttgctgga ggtgcgcgcc ggcgcgcgtg aggtggccca ggtgccgtgg
    39241 tgcgcggtgc acgtgttcgc cctgcatcgc agtggcgccg gctggctcga tgccagtgat
    39301 ggcagcgact cccttccgga ggagctcgat tggtcccgcc ttccggatcc gcaggccgcg
    39361 ggcgacggac cgttcagcgt ccggattccg gcatcggccg gcgccgcctg gcaggtgttg
    39421 ctgattccgc tgcagatcgg caatggtcag cgactcggta ccctggtcct caccgaccgc
    39481 gccgcagccg ccagcagcct gcaacgcagc gaggtcgtcg gcttcctggc cgcgcttgcc
    39541 ggttccgcgg cgatcgcgct ggagaaccag cgtctcctcg acggtcgcaa ggatctgttg
    39601 cacggcgtga tgcgcctcat cgccgaggcg atcgatgcca agtcgccgtt cacgggcggc
    39661 cattgccggc gcgtaccgca gatcgcaacc cgactggcgc gcgcggcgca tgatttcgac
    39721 agggggccgc tggcggccta ccggctcgat gcctcgggct gggaggcgct gcagatgggg
    39781 gcgtggatgc acgactgcgg caagctcacg acgcccgact acgtgatcga caaggccacc
    39841 aagctcgaga ccctgcacaa tcgaatccac gagatccgta cccgcttcga ggtgctcaag
    39901 cgcgacgccg aggtcgccta ttggaaaggc gtggcgcagg ggctcgatga ggggacgctg
    39961 cggcagcgac gcgacacggc ctggcaagtg ctcgacgagg agttcgcgtt cgtcgcgcgc
    40021 tgcaacgtgg ggggagaggc gatgacggag gcggacgccg aacgcctgcg gcagatcgcc
    40081 cggcgacgct ggatgcggac cctggacgac ggcctcggcc tgtccaccgc cgagctggag
    40141 cgccgcgcgc acctgccgga gcgcccgcct ccggccgagg aggcgctgct cgcggatcgc
    40201 cccgagcata tcgttccgcg tcaggacagc acgcgctttg cgcccgggaa cccgtggggg
    40261 ttctcgatgc ggccgcccgc tgcactctac gatcgcggcg agctgcacaa cctcaccgtc
    40321 gcgcgcggga ccttgactgc cgaggagcgc ttcaagatca acgaacacat cgtcgagacc
    40381 atcctgatgc tcgagcgcct gccgtttccg ccagacctcg ccagcgttgc ggaaatcgcg
    40441 gccgggcacc acgagacgat ggacgggcga ggctatccgc gcggcctgtg cgcagcggcc
    40501 ctgagcgtcg aggcgcgcat catcgcgatc gcggacatct tcgaggcgct gactgcacac
    40561 gatcgtccgt acaagaccgc gcacagcgcc gacgaggcgc tcgccatcat gcgcaccctg
    40621 tgtgcccgtc gggtgatcga ccccgatctg ttcgagctct tcgtggcctg tggcgcatgg
    40681 cgggacgatg cggctgcggg aggcgaagcg gcaacggcgg cctcggcgat gcagccgccg
    40741 gacgcacatt gagatccagg gccggccccc cgcccgcagc gcaagcgggc tgaccgacag
    40801 gacggcctac ttcttcggtc gcccggtctt gatgcgctcg atgcggccga ccgcctcgag
    40861 gaatgccgcg tcatcggcga gcgccagcat ggccagcccg gcgcgcagca gctcgctctt
    40921 cttgacctcg gcgccgcttt tgagggcacg ctgcttcagg ctggcgaaga gggcgtagtc
    40981 gttctctggc agggtgaagc tgtcgcgaac gagcttgggc tttgcaggcg catgcttttt
    41041 cgccttggtg gccttggtgg ccttgggtgg ttctgcgggg gccggggcgt cgaccgcagc
    41101 ggcattcttg accggcggtg cagcccgctt ccttgcggga gcgggcttcg aggcgtccgg
    41161 cgcggcgctt gcaacgggag ccggcgcctt tcgcggcttt gccttcgcag cgggcttcgc
    41221 cgggcttttc ggggtggccg gcaccggcgc ttcggtctgc ggggggaccg cagccggggc
    41281 ggcggccgtc gcgggcgcct cgtccgtctt gggcgttgcc tggatttctt cgttcacgtc
    41341 gctctcccga gcaggtttaa aaagggataa actgtataaa caatttataa ctttagcgtc
    41401 ccgagagcaa tcgaaatgcg caggatcatg gtggccaatc cgaaaggggg cagcggcaag
    41461 tcgacgctgg ccgtgcatct ggcgagctgg tttgcgagga acgacgagct cgtctatctc
    41521 ggcgacctcg atcggcagca gtcgaccgct cgatggctgg ccggacggcc gcgcagcctc
    41581 gcgcccatcc gccactggga catcgcgggc gacgagttcg atgcgccacc caaggactgc
    41641 acggtggcga tcctcgacac gccggcgggt ctgcatggca aacgcctgaa gctggccttg
    41701 agcgcgatgg acaggatcgt ggtgcccgtt tcgccgtcgc gcttcgacat gctcgccagc
    41761 cgcgacttct tcgaagagct cgccgagacg aaggcggtgc gcaaggaccg ggtggacatc
    41821 gcgatcgtcg gcatgcgggt cgatccgcgc acgaacgcct cacgcctgct cgtggagtat
    41881 ctgcagcagt tcgacctgcc cctgatcgcc tgcatacgac agtcgcagcg ctacgttcag
    41941 gcggtcgaga ccggggtgac gctattcgat ggcaatcgga tcgatcccgt cgatcagctt
    42001 cactggaggc cgctgctcga ctggctggtc aggcgacgct gaatcggccg gcgagcggct
    42061 gtcgccgctc gcgatgctcg acgcgagctg cccgcgagca gggcaggccg agctaccagg
    42121 gagtgcgccc ccaaagcacg ggcctcgtct cttccagcac gcggctgcgc aggcccgaat
    42181 agcgcgggcc atgccacccg agcacgaagc cggcggccag cgacagcgag ggggccgcgt
    42241 gtgcccagat ctccaggcgg ccgcgcgcca cctccaggtc ctgcaggaaa ccgagcgtgg
    42301 tctgcgcctg ggtgagccgc tccaggtagg aacgcaccgt cttgcgaccc agcaggggcg
    42361 cgaagaactc gaccgcgtag cgcagatcct tcaggccgat gcgcagccgg tgcaactgtg
    42421 cgggctcgag actcgacgcg gcattgaagc gctcgcgcgc gcgtcgccgc gcgcgaacca
    42481 gccgttcccg ggcgaattcg gtcagctcga gacctggggc gggcccgcgt cgtggcagtt
    42541 ggagcaggtc ggcattgaac gcgagggcaa tgcgtgcctg ctcttcggga tccagggcgc
    42601 gcttcgccgc ttcgttcgcg gtgtgtcgtt cccgatctac gacgtcgacc agatcgcgaa
    42661 acgcgaccgt gccgatcagc cattccggtg cgatggcgtc gagcagctcg gtgcggagga
    42721 catcgagatc ccgcgccggc ccgaaacggt cggcgttgtc gcgaaggcgc tgcggccacg
    42781 tctcggtgaa ggcgctgggc aatgcaggcg caaagacctt cattgcggac cgcagccgtc
    42841 tcagcgcaac ccggatctga tggatgaatt ccgccgcctg gtccgcctcg gcgtgcgacg
    42901 cgccggcgac attgccctgc cactggcgga cgcacgatcg ggccagggcg acgaaggctt
    42961 cctcgaccgt cagcccgcgc tgcagaggag aggtttccgc atgcagaggc tgcggctggc
    43021 ctgcttcggg gatgcctcgg tcctggtcct gaaccatctc gcctacctcg ggagaagtgc
    43081 acgaagccat tgaacaacac gcgtcggaca aggataagac agtttgcgga ggttcgagcc
    43141 gcgcggttcc ggagcggcgc ttgcgacgga cggggtcctg gcacggcatg cggatcgcgc
    43201 cgggcgcccg ccccgcgacg gcagtcgtcg actggaatgg ccgtcacatt cgaggcggac
    43261 aatggcgggt tcattcagaa gctgacggtc gctcgttgca gtaccgacgt cgtccctgcg
    43321 cgtgcggctt cggcagacct cgcggcttct gtccgcaccg aatcgtggaa gcgtttcatg
    43381 agcatccgac aaaacctcgt tgtcctcatc gtcatcacgg cgaccttgct gctgtccatc
    43441 ggcgtgatcg gcaagactca gttcctgcgc catgacgaga tgacccggac cctcaccgac
    43501 aatgcgatcc cgggggcgct ggtcgcggcc gacctcgtcg ccgatctcaa gcaggccgaa
    43561 ctcgacctga tcgaactcgt ctttgcaccg gatccggaca tcgccgcgaa ggcgcaggaa
    43621 cggctgcgca tccagcagga acgggtgtcc gcgaatctgg atacgctgga acggctgccc
    43681 tcgacggcca aggagagcgg cctgctcgaa catgcacggc agcggcttgc agattaccgg
    43741 gccgccaccg acgaggtgct tgcctatgct cgagcggggc agcgtgtgtt ggcggaagcg
    43801 agcctgtacg ccaacgtggc cggctacaag gacgaactcc agcaggtgct cggcgacctc
    43861 cgcgtcgaga agggccgcag caaggacgcg tcggtggtcg cggtgcggga agagcttgcg
    43921 cgcacgatgc gcgtgctggg ctgggccggc ggcgtcacgc tgctgatcct ggtcgcactg
    43981 gtctcccgcc tgcaccgcag tatcgtgcga ccgctgcgtg cgatggaggc cacgatgacg
    44041 gacatcgccg tgtccctgga tttcacccgg cgcgtcgccg tgagccggaa cgacgagatc
    44101 gggcagtccg tgcgtgcctt caactccttg ctcgacaccc tccagcacag cctgggcgcc
    44161 atcgtcggca tcatccgcag caacgagagc gcgacggccg agatgcacca gtcggcgctg
    44221 gtcgtggcgg acatcgccgc ggagggcggc gatgcgtcga agcgcatcca gcacgccgtc
    44281 cagtcgatcg agcagcatat cctcgagatc gaccgggagt cgcggcaggc cggccggatc
    44341 accgaggcgt cgagccagga ggcttcctcg cgcagcgcgg tgatccgcga gacggccaac
    44401 cggatcgatg cactggccgc ccatatcgac gccgcctcgg cgcaggtgtt cgcgctcgcc
    44461 ggtgaggtgg gcgagatcga gagcgtggtc accgagattc gccagatcgc cgaccagacc
    44521 aatctgctgg cgctcaacgc cgcgatcgag gccgcgcggg cgggggagac ggggcgcggc
    44581 ttcgccgtgg tcgccgacga agtgcgcaaa ctggcggaac gctcggctgc cgcgaccgag
    44641 ctcatcaacc agcgcatcgg tggcatacgc cgtgcctcgc acgactgcac cggactgatg
    44701 cagcgggtcg gtgtcgagat ggagcagagc acgagcctgg cgcgctcggc gggcgaggcc
    44761 atcgaatcga tcgagcagtc ggcgacgagg gtgatcgacg tggtgggcga gatcattcgc
    44821 ctggtgcaga tcggtcagcg ctcgggcggg gagatcgtcg cgcaggtcgg cacgatcgac
    44881 gtgttgctgg accgggcgca gcaggcggcc gcgcacacca agcttgcggc cgaccacata
    44941 cgcgggattt cccgcgacct ggccacgatc gtcgcgcgct tccggatcga gcagccgtct
    45001 gggtccgcag cgggttgatc cgctccggcc agcctcggcg gcgacccacc gtgccgcccg
    45061 gtctcggcgg cgaagcctgc ggcgcggtcc gcgccgaggc aatgccgcaa acccgagtcc
    45121 tggccattgt ctcgaaatcc ggaacagtgt ttcgtctgga tgatggttta tcccactccg
    45181 gcggcgccgt aaagtgctgt ccatggtcgc acaccggctt gcagcggcgg gcccgatgcg
    45241 gacccggatc gatgccggcc ggccggcgag ccagagccat ggccgcgcaa ctggagaacc
    45301 ctgatgcaag cactgcccac cctgttcgtc tcgcacggcg cgcccacctt cgcgctcgaa
    45361 cccggcctcg ccggcgccaa tctcgccgcg ctcggccgtc ggctaccgcg ccctcaggcg
    45421 gtgctggtcg tgtcgccgca ctggatgacg cgccaggcgc aggctacgct gtcgcttcgg
    45481 cccgagacca tccacgattt cggcggcttc gatccggccc tctacacgct gcagtacccg
    45541 gccgaaggcg cccacctcgc cgcacgccgc gcgctcgagc tgctgcaggc ggcagggctt
    45601 cccgccaccc cgaatgccga tcgcggcctc gatcacggtg cctgggtgcc gctgatgcac
    45661 ctgtaccccg aggccgacat cccggtgttc caggtgtcgc tgccggagtg gctcgatgcc
    45721 gatggcgcct atggctacgg gcgcgcgctc gcgccgctgg cggacgaggg cgtgctgatc
    45781 gtgggctcgg gcagcctgac ccacaacctg tacgagttcc gcctcggtga tccgcgcgca
    45841 gaggcctatg cggcggagtt cgcgcactgg gtgtgcgacg cggtgctggc gggcgaccac
    45901 gcgcgcctgc gccaggcgct cgcgatcgca ccgcatgccc gccgcgcgca tcccaccgcc
    45961 gagcattacc tgccgctgct ggtggccgcc ggcgcggcgg cgcaggccct gcccgcgagc
    46021 gtcatcgaag ggggcatcgt gcatggcgtg ctgtcgatgg attccttcct gttcggtagc
    46081 gacctccgct tgatgcaggg tgccgacgcg aacaaggcat tgccccactg aggcccgacc
    46141 atcatcgccg aggtcctccc ggatctgggg caggatgcgg atgcacgcgt ggccggtcgt
    46201 gtgaaggcct tggccgcccg agtcggccgc ccttgacagt gcccgcttca gctcgccgtt
    46261 gaagcgagta ctctcagtcg cggctgggtg cccacgtgga tgccgctgcc cgattccttg
    46321 gcggccttct tggcaacggc agcggccgag gcgacctctt ccggactcat gaactggccg
    46381 tcggtgatct ccacgatgcc ggcggcaatc gtggtgagcg ggaagaaggt cttgaagccg
    46441 cggcggtcct cgctctcgaa accgttgctg gcgagttcgg ggccatcgaa gagcgcgcgc
    46501 gcgcgcagat tgaagtcctg cacggcggcc ttgcagcgct cgcgccaatt ctcgctctgg
    46561 aacagcgcca cgaaatcgtc gccgccgacg tggccgacga agtcctgcga cagatcggca
    46621 ttcttcacga tgacctgggc tgcgagcttg atcatctcgt ctcctcgcca gtagccgtac
    46681 aggtcgttgt agggcttgaa gttgttcaag tcgaagtacg ctgcggcaaa ggggacctgc
    46741 gagtcgagca ggcggcgaat gtgctccgtg atcggaatgt tgccgggcag gaaggtgagc
    46801 gggttggcgt ggcgcgccgc ctcgatccgg cgctccgtca ccgcgcgcac caggctctcg
    46861 ccggtggcga gcccggcgta gcggccgtct tcggtgatga tgaagccttc gtacagataa
    46921 cgctggtcgt cacccgacag caccgggatc agtgagtcga tcgtagccgt cgcctcgacg
    46981 cgcagcgggg tggcgttcat gaacagggtg catggacggc gaccatagag ctcgcgcgaa
    47041 tagggttggg cgaacttgtc gacgaagccg cggcggttca ccaggccgac cgggtaatgc
    47101 ttgtcgacca ccgcgaccgc atgcagctcg gaatggttcg tgaacaactg catcaggtct
    47161 gcgttggaca tgctggagca gaccgtcggt gcgggcacct tgaggcgtcc gatggtgtcg
    47221 gcaatatccg ggcggggaga ggagttcggc agcaccgaga tcttcgacga gctcagcacg
    47281 gcacgcgcct ccttgccgat ctctgcagcg ggcgaggccg tcggtcgggc aaaaagatag
    47341 ccttgcccga agtggcagcc cagatcgcgc aggacggcca gctcttcggc gacctccacc
    47401 ccctctgcca ccagcggcgt gccgaaggtg gtgcacaggt ccaggatcgc ccgcacgacc
    47461 tggaccttgc ggctgtcgag gtggatgccc cgaacgaaga acttgtcgag cttgacgatc
    47521 tggggcttga gttccgccca caggcgcagg ctcgagcgac cgtcgccgaa atcgtccagc
    47581 gccaggccca ccccctgacc ggaaagggtt gcgaatgccg cgcgcaaggc gtcggcatcg
    47641 tccacgcgct cgtgttcggt cagctcgagg atgagccggg agggcggcag gcccgtgtcg
    47701 accgcgcagc gcaacaaggc gccgccgcct tcgcgaccaa aggccgcaat cgacgatgcg
    47761 ctgaggttga gaaagagctt atgaaggccg gcgaaggcct ggatcgcacc cttgcaggct
    47821 acggcctcga gttccaggcc gagattgcac gccttcgcca tccgcagcaa ctcgtcgggg
    47881 cgctccagcg gcgtacctgc aggcccgcgc atcaaggcct cgtagccgag cacggtcgat
    47941 cgggcgatgt cgacgatcgg ctgaaagacg aagcgcagct tgtcctggtc gagaatctgg
    48001 cgcagcttca gggtaagtcc ggcgttgtac aacatgctgg ttccgcgtac gaggcaacgc
    48061 ggcaggatgg catgtgggca ttaagctgcg atgaagccga tccgcttcca cgagcggggc
    48121 cgtgtgcttt agggcgggat cgttcgggcg cgaggacaag atcgcgggcc acctttaggc
    48181 ggcccgcaag cgcgaggccc gggtggccgg ggcggaaaga ggacctcggc ccgctcacga
    48241 tagaagcccc taaggaaacg cgtggcagcc ccgaatggat agggaccgca gggaggcagt
    48301 acccgacgca gatccagatc atgcaagcgg gtggcagacg acgaattgta ggacggggtg
    48361 gattttgtag aacaaaggcc cctgtggatc actccacagg ggccttgctg tacttggggc
    48421 gacataccgg aatcgaaccg gtgacacctg gagccacaat ccagtgctct accaactgag
    48481 ctaatgccgc cactgtggaa ccccggagaa ccggaattcc gataaacctt tcctggcctg
    48541 cccggcaggg atcgaacctg caaccgccgg cttagaaggc cggtgctcta tccaattgag
    48601 ctacgggcag cttccgacgg gcagtcggga tgtgagctgg tcggggtgga gggattcgaa
    48661 cccccgacat cttgctccca aagcaagcgc gctaccggac tgcgctacac cccgagagcc
    48721 gcgaactata cagatgcctt tttgcttcgt caaacaaaat ttgcgcgctg cgaaaaaacc
    48781 ctggaatcac gtgctggcgt ggcttccggg gcgcggtacg gcggccttcg ctgcgtcgcg
    48841 gcgggcacgc accacgcgca gcaggttggc gaagagccag ccgaattcga ccgccagcac
    48901 gatgccggca accggggcga ggatcggcac gaagaccgcg aggcagagcg tggcgaggct
    48961 ggcgctgcgc acgcggagct ggcggcggat cggggtgtcg ggcagcagct tcttcatgtt
    49021 cggcgccttg agcccggcct gggtgaggtg cagccaggcg aggaagggca cgatcttgta
    49081 gagcatcgcg gtgatggtgc cgccgaagcc gccgtgcagg atcagcacgc cagcgaggat
    49141 cggccaccag tcggcgtcgg accacagcga gatcaccagc acgaggacgc cggcgagcgc
    49201 cgcgtacatg gcctcgcgga aggcgaggaa gggcgtgtcg ggcttgctgc ggcgcgagtg
    49261 cgcctgcagg tacagcgtgg tgcccgcgta gccggcgccg agcaggccga gcgcgatgat
    49321 ggcgatgaag cgcgcggtgt cgatcgcgaa gtattcggcg agggtccaca acacgagcgt
    49381 ggcggtgacc gccggcgccc acagcgtggt gaagcgttgc ggataggccg cggtgatctg
    49441 gaacatcggc accacgaccc agctcgcggc ggcgagcagt accgcggccc agcccatcca
    49501 gccccagccg gcgtgcaggt tgaccacggt cggcagtggc accggcagcg cgaggccgcg
    49561 ggtgagcacg agcaccaggc tgaagccgag cgcggcggtg acgacgaggc cggcgaatgc
    49621 catgcgcagg tcgcgcgggg tgcgggtgtt gttgccggtg cgtgcgccgc ggctgaggcc
    49681 gagcgcagcg gcggagagga agacgaagag tccgcccacg aggagtacgg cgccgccgag
    49741 caggacatcg ggcgcgccgg cacccagccc gtaggcgagc ccggcggtgc cgagcgtcat
    49801 cgccacgtgg gtgacgccgg caatgcgcag cggcgcgggc atgctcgcgc ccgccaccac
    49861 cggcatgacc tgcagcagcg cgccgagcat cacctgcagc atgaagccgg cggcgaagag
    49921 gtgcgtgatg gcgagcgcgc cgggcgtcca ccgcgagacg aggatctctc cgccgaagag
    49981 cagcgtcagc cctgccacca ccccgaacag cggggcggtg aggaagaagc ggaccggagc
    50041 ggagaacggc ggggtgtcgt cgtaggagag gcccggcccc atcatcgctg gcgaatccgg
    50101 atctcgaccg cgccgtcgtc gcggaaggct tcggtgtggc cgtagccgtc gcgatcgagg
    50161 atgcgcagca gcgggtgcgg catgcgatcg aggatgagca gcatctcctc gtccttggcg
    50221 agggccatca gtccttccat ggcgcgctcg aagggctcgg gcggctccag gccgcgggca
    50281 tcgacgacac gtccgctcat gctgcgcggg cctccacgag gtgcttgccc accgaggccg
    50341 acaggcgctc ctgctcgtcg ccgggcaggc ggctgtcgag catcgggtag atcacgctct
    50401 cttccttcat gttgtgctgc tgcatcatga tcagcagggt ctcggcctcg ccggcgaagt
    50461 cgtcggcgtc ctgcttgtcg agggcgtact ggagggcggc cagggtgtcg cgcatgttct
    50521 ggtgttcgtg gcgcatcacc atggtggggc cctgggtcat gcccgtggcc tgctcgaagg
    50581 ccgggaagag ggtgctctcc tcggcgtcga agtgggcgtt gagcgcatcc gcgaatttct
    50641 tcagcgcggc ggccgcgtcg gcccagtcgc cgtcggaggc gagctcctcg gcgcgggcga
    50701 agatgccgtc acagtcgcgg tggtcgtggg tcatgagttc ggaaatggta ttcatcggag
    50761 tctcctctct ggcgggtgtt ccgaattctc cgcagggggc gacaaacggc attgatgcaa
    50821 gtcaagggca ttccgatatg ttggaactgc aacaatttgt cctgcagcag atgcgtctac
    50881 gcttgggtgc ggtgacgctt gcaggcacaa tgcgggcttt tttgccgggg gcgcgggtgg
    50941 tagacgagag gcggtggggc ggggcggaac atggccggac gcgcgcctgc acgagtggct
    51001 gggtgcgcgt gttcctgccg ttcgcgctcg gctactacct gtcctacctg ctgcgcacgg
    51061 tcaatgcggt gatctcgccg cggctcaccg acgagctcgg cctgtcggcg gccagcctgg
    51121 ggttgttgac cagcgcgtat tttcttgcct tcggggcggc gcagatcccg gtcgggatcg
    51181 cgctcgaccg cttcggcccg cgccgggtgg aggccgcgct gctgctgctc gccgcgctcg
    51241 gcagcgcgct gttcgcgacc gccgattcgc tcggcgcgct cgcgggggcg cgcgcgctgg
    51301 taggcctggg cgtatcggcc tgcctgatgg cggcgctgaa gggattcgcg ctgtggtatc
    51361 cgcccgagcg ccagagctcc atgatcggat tcatcatggc cgcaggttcg ctcggcgcgc
    51421 tcaccgccag cgtgccgctc gaggcggtgc tgccggtgct gggctggcgc ggtgcgttct
    51481 ggatcatcgc cgcggtgtgc ctgttggcgg cggtgctcgt gctgcgcgcc ttgcccgatt
    51541 cgcccgccgc ggcgggcgag ccctcgctgg cggcggcgct gcgcgtggtg gcgggcatct
    51601 tcgccgcccc cgccttcctg cgccatgccg cggcctcggt gttcttcgtc ggcggcttca
    51661 tggcgctgca gagcctgtgg gtggtgccct gggtgatgaa cgtgaatggt ttcgacctcg
    51721 ccggggcggc gacggtgctg gtcgccctca atctcggcaa ccttgccggc cagctctcgg
    51781 tcgggttctt cggcgtgcgc ctggcgcgcg ccggcgtcga gccggtgagc ctgctgcgtg
    51841 ctggctacgg ggcgatgctg gtggtgcagg ggctgatcct gtggtcgggc ttgccggtgc
    51901 tgctgctgtg gacgctcttc ggcctgctca ccgcggccaa ctcgcagatc tacctgtcgg
    51961 cggcgcgtgc ctttccgccc gcgctgttcg gccgcgtcag caccgcgctc aacctgatgg
    52021 ccttcgccgg cgccttcgcc gtgcagtggg gcttcggtat cggccttgat ttcatgcgcg
    52081 acgggggcgt ggagctgacg cgcgcgctcg ccttcggctt cggcggtctg ctcgtcctgc
    52141 agctgttcgc ctacatgccg ctgctcgggc acgtggcggc gcatcggcgc gagggcggtg
    52201 cgtgagcgcg tgcgcggtgc gtttcgcgat gttgcgtgtg cacaccttcc ttacccgagc
    52261 gtcgcaaagc ggcgcaaaat agcggcctgc cgccttcctg cgcatgccat gcgggctcct
    52321 gccgcatgat gtgcgggcag ttccagcgac gaattcatcc tgatggagct tcccatgcct
    52381 gaacccacga ccgactcgac cgtgcagccg ccccggcgca aggggatgcg tcggacgttg
    52441 tggacggtcg cgatcctgct cgcgctgtcg gccgccgcct atctcgccgt accgccggtg
    52501 gcgcggcact acacgcagaa gctgctcggc gagacgctcg gtcgcgaggt cgtcgtcgag
    52561 cgcgtgctca tcaacccctt ccgcctcacc gccgaggtgg gcgggctgcg catcatggag
    52621 gccgacggca gcaccgaggc gctgggcttc gaatcgctgc gcgccaacct cgagctcgag
    52681 tcggtgctgc gcaagggcat cgtcctgcac gagctcgcgc tcgacaagcc gcgcgtacac
    52741 ctcgcgctcg aggccgacgg ccgccacaac tggacggacg tgctcgaacg catcgccgcg
    52801 ctcggcggcg aggagcctgc agaggacgtg ccgccgacgc tgttctcgat cggcaacatc
    52861 cgcatcagcg acggcctcgt ccgcgtcgac gaccgcgtgc gcggcatcac ccacgagctc
    52921 tccgaactgg gcgtcggcgt gcccttcgtg tccaacctgc cggtgcgggt ggatgtcttc
    52981 gtgcagcctt cgctgtcggc caagctcaat ggcgacgcgc tgctgctcaa cgcgcgcacc
    53041 aagcccttcg ccgaatcgca ggagaccatc ctcgatgtcg cgctgaagga gttcgacctc
    53101 acgccctggg tcgcctacct gccgatcgag ccgcgcttcc gcctgccctc ggcactgctg
    53161 acgaccaatg tcgagctctc cttcagccag caggccgatg gcgcgccggt gctgtcgctg
    53221 cgcggccccc tgcaggtcga caggctcgtg ctgcaggatc gcgacggcgc gccggtcgcc
    53281 agcgcggacg aggtcgagct cgagttcgcc gacgtgcagc cgatgatcgg gcgctggcac
    53341 ttcacccggc tgcgcctggc gcgtccggag atcgatctgg tccgcctgaa ggacggtggc
    53401 ctcaacgtgc ttgggctgat cccgccgccg gccgccgagg gcgcgaggaa gaagggcaag
    53461 gccgcgagtg cgaccgtgga caaggctgcc gcgccggtgg cgaaggagcc cgtcgagccg
    53521 gccgtggccg ccgcgcgggc ggggacgccg ccggccgtgt cggcggacgg aaagacggtg
    53581 gccgatgcga gcgccgcggc tccggctgcc ccggccaccc cggccgggcc tgacttcctg
    53641 ctcgcgctga tgcgtatccg cgacggcgtg ctgcgcttcg aggaccgcag cctggccgag
    53701 cccttccgcg cgcgcatcga ggcgatcaac ctcgacatgc gcgacctcgc caccgagggc
    53761 gaattgccgg ccgagatccg cctcgattac gtcagcgacg ccggcgagaa gttcacccac
    53821 gaggacgtgc tgcgcctgtc gcctttccag tattccggca gcctgcagtt cgagtcgatc
    53881 cgcctgccgc gctatgcgcc ctaccttgcg gcggcgatgc ccggcgcctc gatcggcgag
    53941 ggcagcttga gtggtggcgc gcagtaccgc gtgactctcg gcaaggacgg tgcgccggcg
    54001 gtcgaggtga gttccgaggc gctcgcgctg cgcgacttcg cgctagtgct caagggcgcg
    54061 aagacccccg ccctgagcct gccggcactc gacgtgcgca gcgccacggt cgacctcgcc
    54121 gggcgcagcg tgcgcatcgg cggcgtcgag ctcaagggcg cggcggtgtc ggcggtgcgc
    54181 gccaaggacg gcgagttcga cctggtgaag gcgctcgtgc cgccgccggg caaggccgac
    54241 aagcccgcgg cacctgcggc gaaggtcaag gccgaacccg actgggtggt cgcggtggat
    54301 aagctcgcgc tgcgcggcgc ctcagtgcgc ctggatgatc gcagcgtggc gcggccggtg
    54361 gtgaccacgc tcgagggcat cgacttcgag ctcgacggct tctccacgga gaagggagac
    54421 tccatccagt tcaagctcga ctccaggctg aacaagcgcg gcaaggttgc agcctcgggt
    54481 ccgctgacga tcgcgccgct caaggccgat ctcgcgctcg atctgcgcag cgtcgacctg
    54541 ctgccgttgc agccctacgt gctcgagcag accaagatcg cgatctcgcg cggcaacctc
    54601 accaccaagg gccgcctcaa gctcgacacc gaccgccgcg gcaagctgct tgcgagcttc
    54661 aacggcgacg tcggggtggc gaacttcgcc tcggtcgacc gcttgaacgc gaccgacttc
    54721 ctgcgctggc gtacgctcgc gatcggcggc atcgacgcgc gcctggagcc gttctcgctc
    54781 ggcgtcaaac gcatcgcact ggatgatttc tacacccgcc tgatcctgga caaccagggc
    54841 cgcctgaacc tgcgcgagat cggcggggtc aagggcgagc ccgagccggc cgcgaagccg
    54901 gccgccgcgg tggcccggac gacggagctc gacgagggcg gggtgcaggc cgagcagcgc
    54961 gccgagggcc agcgcaccgc cccggtcgcc cccccggggc cgccgcctcc gccggtgcgc
    55021 atcgaccgca tcgagctcaa gcgcggcaac gtggccttca gcgaccgctt catccgcccc
    55081 aactacgacg ccaacctgac cgggctcgcc ggcacgatca ccggcttttc gaccacctcg
    55141 gacaagctcg ccaaggtgga catctccggc aaggtggaca agagcgcgcc gctgtcgatc
    55201 accggcgagc tcaacccctt ccgccaggac gcccacctcg acatcctcgc ctcggtgaag
    55261 gacttcgagc tcaccgggct gtcgagctac tcgggcaagt acgtcggcta cggcatcgcc
    55321 aagggcaagc tgtcggccga gctcaactac aagatcatcg agcgccagct caccgcgacc
    55381 aaccgcatct tcctcgacca gctcaccttc ggcgacaagg tggacagccc ggatgcggtg
    55441 aacctgcccg tgcagctggc ggtgtccttg ctcaagaaca gccgcggcga gatcgacctg
    55501 cgcctgccgg tgacgggcac gctcgatgac ccgcagttca gcgtcttcgg cctggtgatg
    55561 aagatgctgt tcaacctgat cggcaaggcg atcacctcgc cgttcgcgct gctcggctcg
    55621 gcgctcggcg gcggcgagga gctctcgcag ctcgacctcg ccgcgggcac cgcggcggtc
    55681 ggcgaggcgg agcagggcaa gctgaagacg ctcgcgcagg cgctggtcga tcgtccggcg
    55741 ctgcgcctgg acatcgtcgg tcgcgccgac cccgccaccg acctcgacgg cctgcgccag
    55801 gccgcgctga ttaacgcggt gcgcgcgcag aagctcaagg cgatgatcgc caagggccag
    55861 gccgcgccct cgctcgagga ggtcgaggtg ggtgaggcgg agtatgccga gctgctgaag
    55921 aaggcctacc gtgccgcgga cttcaagaag gagcgcaaca tgatcggcat ggtcaaggac
    55981 atccccgtgc ccgagatgga ggcgctgctg cgcgccaacg cgcaggtcgg cgacgacgac
    56041 ttgcttgcgc tcgcccgcgc gcgcgcgcag gccgtgcggg attggctggc gggagagggt
    56101 ggcgtgcccg gcgagcgcat cttcgtgctc gagcccaagg tcgaggcctt gggcgagggc
    56161 ggcgaggtgc agttctcgct gcgctgaacg ccggcggccc tcgcgcctgc cggcgctcca
    56221 acatgaacca tcgtgcttcg gcgttggtac gacgatcgtc tgcttaggcg ttcgtacatg
    56281 caccgtcgcg cttcggcgtg ggtacgtg
//
LOCUS       DAOTIN010000010        53404 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_613_length_53404_cov_9.135541, whole genome shotgun sequence.
ACCESSION   DAOTIN010000010 DAOTIN010000000
VERSION     DAOTIN010000010.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 53404)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 53404)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53404
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_613_length_53404_cov_9.135541"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..169)
                     /locus_tag="P5537_02805"
     CDS             complement(<1..169)
                     /locus_tag="P5537_02805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004384785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HRV77002.1"
                     /translation="MTAAPASAATLPATEAGADARFSNTFLRLKKKLERGVGEAIGDY
                     NMIGDGDTVMVC"
     gene            complement(236..1021)
                     /locus_tag="P5537_02810"
     CDS             complement(236..1021)
                     /locus_tag="P5537_02810"
                     /EC_number="1.5.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pteridine reductase"
                     /protein_id="HRV77003.1"
                     /translation="MHTPPFELHSATESEPAAAPLILVTGAARRVGAAIARRLHAGGA
                     RLALHYRHSAAEAEGLAAELCALRAESAFTVGGDLARFGAAAEIAAAVLARGGRLDGL
                     VNNASSFFPTPLGSIDRAAWDELMGSNLMGPLFLTQALAPALREARGAIVNIVDIHAQ
                     RPLAGYPVYCAAKAGLAALTRSLAIELAPAVRVNGVSPGPIEWPEDEQFPPAERERIV
                     AHTLLGRVGSPDDIARTVAFLMFDAPYVTGQIIAVDGGRSAHL"
     gene            1113..2288
                     /locus_tag="P5537_02815"
     CDS             1113..2288
                     /locus_tag="P5537_02815"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002931522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HRV77004.1"
                     /translation="MSSLPQPSADALAQSARLLETIEAELAAAGGWIPFARYMELALY
                     APGLGYYSGGARKFGPGGDFITAPELTPLFGQALAAQVEQVMRASAPALIEVGAGTGL
                     LAADLLLELERRDCLPESYGILELSGELRERQFDTLAAKAPHLAARVQWLDALPERFA
                     GAVVANEVLDVMPVHLVVSRAEGLFERGVAIAADAAGARRLCWADVPAAGAVAEAALA
                     LALPVPQSGEYVTELNLAGKAWVAAWAERLQAGALLLIDYGYPRAEYYLPSRSGGTLL
                     CYYRHHAHGDPFLWPGLNDITAFVDFTAVAEAGFEAGLDVQGYTTQAQFLFNCGVLEC
                     LERRGARESADYIRAARAVQRLTAPQEMGELFKVIALARAIDGPLLGFARGDRTHAL"
     gene            complement(2305..3108)
                     /locus_tag="P5537_02820"
     CDS             complement(2305..3108)
                     /locus_tag="P5537_02820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004306727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HRV77005.1"
                     /translation="MNATRFGELEVLCHAPERATHEHPLLFIHGAYVSAWCWEEHFLP
                     WFARRGWQAYAVSLSGHGRSRQREHLDSYSLDDYVRDVAEVAARLPAPPVLVGHSMGG
                     MVVQKYLEQHDAPAAVLMSAVPPQGLMGSAFGLMFKRPHLLSDLNRIMSGNDVDIDSL
                     REALFHQPVAADDLQRYYRLSQPESHRAIWDMSLFNLPQPARMHRVPMLILGAEHDAL
                     IPPDQVHMTAMTYGRQAEILPGMGHGMMLERDWELGAMRIADWLAERAL"
     gene            complement(3105..4331)
                     /locus_tag="P5537_02825"
     CDS             complement(3105..4331)
                     /locus_tag="P5537_02825"
                     /EC_number="2.7.7.72"
                     /EC_number="3.1.3.-"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004306731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004810 - CCA tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional CCA addition/repair protein"
                     /protein_id="HRV77006.1"
                     /translation="MQAYVVGGAVRDALLGLPVKDRDWVVVGSTPDEMLARGFRPVGR
                     DFPVFLHPHTNEEYALARTERKSGHGYTGFVCHASPEVTLEEDLQRRDLTINAIARAE
                     DGRLIDPYGGRRDLAARVFRHVSPAFAEDPLRILRVARFSARFTDFELAPETLALMRA
                     MVAAGEVDHLVAERVWQELARGLMEARPARMIRVLRACGALARLLPELDRLFGVPQPE
                     QHHPEIDTGEHVLMVIDHAAAAGEPLAVRWACLLHDLGKGDTPAHALPHHYGHEAASA
                     RRAREVSERLKAPADCRDLAELVAREHGILARAAELRAETMVKLIERCDGLRRPQRFL
                     LMLQAAACDHAGRGDGTENASEWRPLSRWQAALQAVRAVDAGRIATECSDKSLIPQAL
                     HAARVAAVKALDKDPA"
     gene            complement(4331..4975)
                     /locus_tag="P5537_02830"
     CDS             complement(4331..4975)
                     /locus_tag="P5537_02830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase family protein"
                     /protein_id="HRV77007.1"
                     /translation="MKLIIGNKNYSSWSLRAWLAAREGGFTFEEIRIPLFIPGSRDRI
                     LSHSPSGKVPCLNDHGAVVWDSLAIGEYLAEKRPGLLPGDPVARAMARSVTAEMHSGF
                     QNLRSRMPMNVRKDYTGFGHSPEVDADIARIVAIWNDCRARFGAEGPYLFGRFSLADA
                     AFAPVAFRFQTYAVKPEGAAGEYLATLLANPHMQEWAAAARAETESIPEEDLYG"
     gene            complement(5001..5957)
                     /locus_tag="P5537_02835"
     CDS             complement(5001..5957)
                     /locus_tag="P5537_02835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="complex I NDUFA9 subunit family protein"
                     /protein_id="HRV77008.1"
                     /translation="MNPKRVVIVGGSGFIGSAIANRLCKEGVKVLIPTRRRSRAGHVL
                     LLPNVEVVEGNVHDVALLARLFEGADAVVNTVGVLHSRPGKPFGPDFARAHVELPQKI
                     VAACRKASVPRLVHISALGAYSDGPSEYQRSKAAGETAIRTGSPEIGWTILQPSVVFG
                     RGDSFLNLFADLARMFPVLPLAGAGTRFQPVYVEDVAEAVWQSLIRDDAAGQTFQLAG
                     PTVYTLRQLVEYVSALVGKPRPIYPLSEKLAMLQARMMELAPQPLMSRDNVRSMKVDN
                     VATGSPQPFGMIPTALETVAPAWLGQAAPRAHYYPFRRHARR"
     gene            complement(6014..7957)
                     /locus_tag="P5537_02840"
     CDS             complement(6014..7957)
                     /locus_tag="P5537_02840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HRV77009.1"
                     /translation="MKKALVAALTAATLLAPASAFAQVGDESGDERIVAAREALRKGD
                     RATLERLAAVREAHPLDAYPRYWLLINRLARADEPVPVAAVQAFLAEEAGSNLGERLR
                     AEWLRRLARDGDWRGFLDAYADLRNPDAELRCNAWSARVLSGDRSVLAELAREWDTLA
                     DADAACDTPLRAAVDAGAVDEERVWWRIRRQIDTRKPEAALASLALLPAASAPAATDL
                     GQAIRSPAPWLDRLPPNFAVTRAGRELALAALVRLAREDVAAARLRLLRIQDRLGAPE
                     RNYAHLALGMHAALDRLPEASALYAAAGDIETTAQQRAWRVRAALRIGDWQAVRAAIE
                     AMPAEEREAPDWIYWLGRAHAAAGRRDAAESVYVRIAGEPHFYGMLAREELGEAFPPP
                     PASAPLPRAKLEEAERDPGLQRALALYRLDLRAEALREWVWGVRERDEQFRLAAAHLA
                     LRNELYDRAINTAELANPRSNFELRFLTPYRDLVEPQVRAQGLDLGWVYGLMRQESRF
                     VVPARSSVGAQGLMQVMPATGKWVADRIGLVGYSQRLLTDPETNVLLGTSYMRLIMEG
                     LDAHPVLASAGYNAGPGRARRWRDAAPLEGAIYTETIPFDETRDYVKKVLANAVIYSA
                     MLEKQPQSLKARLGTIAPGAASE"
     gene            8003..8593
                     /locus_tag="P5537_02845"
     CDS             8003..8593
                     /locus_tag="P5537_02845"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HRV77010.1"
                     /translation="MTSAPLPHEPGARRKRMREHALELRERLPAERRERLSAAIGGHL
                     DTLVGRLRPSRLAFCWPYRAEPDLRPWVQAWLAAAPGRVAALPVVLERHAPMVFRAWT
                     PGVPMPLDRHGIPHPADGEAVEPELVLIPLNAFDDRGYRLGYGGGYFDRTLAVMRTVA
                     VGVGFEIGRVPDTLPQQFDRPMDWLVTEAGVAKPRA"
     gene            complement(8630..10153)
                     /gene="ilvA"
                     /locus_tag="P5537_02850"
     CDS             complement(8630..10153)
                     /gene="ilvA"
                     /locus_tag="P5537_02850"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004306745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - L-threonine ammonia-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase, biosynthetic"
                     /protein_id="HRV77011.1"
                     /translation="MSSTPDYLERILNAQVYDVAVETPLDLAANLSARVHNRIYFKRE
                     DMQPVFSFKIRGAYNKMANLSPQALKRGVICASAGNHAQGVALSAARLGVRAVIVMPS
                     TTPQIKIDAVKARGGEVVLAGESYSDAYAHALELEKAEKLTFVHPFDDPDVIAGQGTV
                     GMEILRAHPKPIHAVFCCVGGGGLIAGVAAYIKRLRPETKIIGVEAVDADAMTRSLAA
                     GRRVALEQVGIFADGAAVKEVGAETFRLCQQYVDEMIVVDNDAICAAIKDVFEDTRSI
                     LEPAGALAVAGAKEYARRNKLRDKSLVAVASGANMNFDRLRFVAERAELGEQREAVLA
                     VTIPEKPGSFRKFISVLGNRNITEFNYRYADAERAHIFVGVTVHNRNEAGRLVEMLER
                     HELPALDLTDDEMAKSHVRYMVGGRAPQAENEVVYRFVFPERPGALMNFLSNLRSDWN
                     ISLFHYRNHGSDFGRVLVGMQVPPADKEAFDAFLQRVGYDYVAETDNPAYRMFLSGS"
     gene            complement(10226..11173)
                     /gene="hprK"
                     /locus_tag="P5537_02855"
     CDS             complement(10226..11173)
                     /gene="hprK"
                     /locus_tag="P5537_02855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004306747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HRV77012.1"
                     /translation="MRQTSLIRLYEAHRESLSLVHVSGPIGARLSVAEERIWPADLVG
                     HLNLIHPTRLQVLGAAELAWAQRQANEKVAHHLNEILSARPPAIIVADGCEVPNILHG
                     ICEAHDVALFTARHPSASVIDQLRLYLSRELAEKVSLHGVFMDVLGLGVMITGDSGAG
                     KSELGLELISRGHGLVADDVVELSRIAPTVLEGRCPEMLQDFIEVRGLGLINIRTIFG
                     ETACRRKMRLRLICHLDRRQPGPDDPCRLPLQQETQDILGVKIARVVLPVAAGRNLAV
                     LLEAAVRSKILKLRGIDSTQEFIDRQARALHAEGAQRAD"
     gene            complement(11142..11627)
                     /gene="ptsN"
                     /locus_tag="P5537_02860"
     CDS             complement(11142..11627)
                     /gene="ptsN"
                     /locus_tag="P5537_02860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011764237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS IIA-like nitrogen regulatory protein PtsN"
                     /protein_id="HRV77013.1"
                     /translation="MSLISQLLPLSNVVVDLDASSKKRVFEQAGLLFENNQGIARSTV
                     FDSLFTRERLGSTGLGQGIAIPHGRIKGLKDAAGAFLRLATPVQFDAPDGRPVDMLFV
                     LLVPEQANETHLQLLSELAQMFSDREFRETLHGAADAAQIHSLFVNWGADAANQPDPA
                     V"
     gene            complement(11764..12087)
                     /gene="raiA"
                     /locus_tag="P5537_02865"
     CDS             complement(11764..12087)
                     /gene="raiA"
                     /locus_tag="P5537_02865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_component: GO:0022626 - cytosolic ribosome [Evidence
                     IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HRV77014.1"
                     /translation="MNLNITGRHVEVTPAIRDYVTSKLDRVIRHFDNVTSVTVILSVE
                     KLKQKAEVTLHVRGKDLFVESDDADLYAAIDSMTDKLDRQVQKYKQKQSEHNHESLKH
                     QVPEA"
     gene            complement(12106..13560)
                     /locus_tag="P5537_02870"
     CDS             complement(12106..13560)
                     /locus_tag="P5537_02870"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HRV77015.1"
                     /translation="MKPSLQLKLSQHLTLTPQLQQSIKLLQLSTIELNQEIERVLLEN
                     PMLEREDGDGGGDYTPAAPPGNAPEREAAREPAAEPAGESITHEGGEGSSEDEGIDWS
                     NVGQGASSRSEDDDEGDYQDIQAAGVSLREHLGQQVALSPLSDRDRALVRFLIEALDD
                     DGYLHQPLEDLLELLPQDAEVELDDLAIALRQVQSLEPAGIGARSPQECLALQLQALP
                     ESAIRALALEIVTNHLELLAERNFARIRKLTGCDDEALREAQALICSLDPHPGSRYST
                     TETRYVLPDVVVRKLRGQWTVSLNQEAMPRLRINRLYASLLQQNRAQGGGLGGQLQEA
                     RWLIKNVQQRFDTILRVSQAIVDQQRQFFDHGDVAMRPLTLREIADQLELHESTVSRV
                     TTQKYMATPRGVFELKYFFGSHVATDTGGAASSTAIRALIRQLVDAEDSKKPLSDARI
                     AEILGQQGIVVARRTIAKYRESLNIPPVSLRKSL"
     gene            complement(13583..14305)
                     /gene="lptB"
                     /locus_tag="P5537_02875"
     CDS             complement(13583..14305)
                     /gene="lptB"
                     /locus_tag="P5537_02875"
                     /EC_number="7.5.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004091254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015221 - lipopolysaccharide transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015920 - lipopolysaccharide transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter ATP-binding protein"
                     /protein_id="HRV77016.1"
                     /translation="MSLLKVAGLQKRYKARTVVHDVGFEVGSGEVVGLLGPNGAGKTT
                     CFYMIVGLVRADGGQITLDGTDLTHLPIHARARLGLSYLPQEMSVFRKLSVAENIRAV
                     LELQGLDRRQVEERLEELLMELGIHHLRDNTAISLSGGERRRCEIARALATDPRLILL
                     DEPFAGVDPIAVIDIQKIIRFLKERGIGVLITDHNVRETLGICDRAYIISEGRVLASG
                     QPTEIIENERVRQVYLGEHFRL"
     gene            complement(14292..14741)
                     /gene="recX"
                     /locus_tag="P5537_02880"
     CDS             complement(14292..14741)
                     /gene="recX"
                     /locus_tag="P5537_02880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HRV77017.1"
                     /translation="MGEPSLRERALRHLARRDHSRAELARKLAPHGETAEIEAVIERM
                     RELGLQSDERYAEAFVRGKAARFGAARLRSELARRGIDRDRIDEALAGECVESEAERA
                     RAVLRGRFSSPPADAREWARQARFLQTRGFAPELIRKLLKEPYDESA"
     gene            complement(14758..15795)
                     /gene="recA"
                     /locus_tag="P5537_02885"
     CDS             complement(14758..15795)
                     /gene="recA"
                     /locus_tag="P5537_02885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004306766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HRV77018.1"
                     /translation="MDENKAKALAAALSQIEKQFGKGSIMRMGDGNVERDIQTVSTGS
                     LGLDIALGLGGLPRGRVVEIYGPESSGKTTLTLQVIAEMQKLGGTAAFIDAEHALDVG
                     YAEKLGVNIQDLLISQPDTGEQALEIADMLVRSGGVDIVVVDSVAALTPKAEIEGEMG
                     DQLPGLQARLMSQALRKLTANIKRTNTLVIFINQIRMKIGVMFGSPETTTGGNALKFY
                     ASVRMDIRRTGTIKKGDEVVGSETRVKVVKNKVSPPFKEAHFDILYGEGISREGEIID
                     LGVEHKIVDKSGAWYAYQGDKIGQGKDNSREFLRANPALAREIENKVRVAVGLPELPP
                     AAASTPAPAEA"
     gene            complement(15984..16472)
                     /gene="pncC"
                     /locus_tag="P5537_02890"
     CDS             complement(15984..16472)
                     /gene="pncC"
                     /locus_tag="P5537_02890"
                     /EC_number="3.5.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide-nucleotide amidase"
                     /protein_id="HRV77019.1"
                     /translation="MTDHELDGLARRVGEALAARGLWLATAESCTGGWIAEAVTAIAG
                     SSGWFDRGFVTYSNAAKADMLGVRDDTLESHGAVSEATVGEMAAGALARSRADLAVAV
                     SGIAGPGGGSAVKPVGTVCIGWARRDASISTTTVQLPGDRAAVRRQTVILALQGVLER
                     CR"
     gene            complement(16477..16959)
                     /locus_tag="P5537_02895"
     CDS             complement(16477..16959)
                     /locus_tag="P5537_02895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HRV77020.1"
                     /translation="MRPTTRLLLSHPAHFISLGFGAGLSPWAPGTVGTLLGWALYPLI
                     RTPVSEFVFLALLASFFLAGVLAAERTGRALGVPDHGGIVWDEMVAIWLVLLFTPPGL
                     LWQAVAVALFRFFDIVKPPPVRWADRSFKGGFGVMFDDLVAAGYALLALAVLVHLQGN
                     "
     gene            complement(16991..17950)
                     /gene="thiL"
                     /locus_tag="P5537_02900"
     CDS             complement(16991..17950)
                     /gene="thiL"
                     /locus_tag="P5537_02900"
                     /EC_number="2.7.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009030 - thiamine-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-phosphate kinase"
                     /protein_id="HRV77021.1"
                     /translation="MPSEFDLIRRHFTRPARHTELAVGDDAALLAPRPGMRVAVSTDM
                     LVAGTHFFADTDPEGLGWKTLAVNVSDLAAMGAEPRWAFLALALPRADEAWIAAFARG
                     FFACADAFGVDLAGGDTTRGPLALSVTIAGEVPAGAAITRGGAHAGDDLWVSGQPGCA
                     ALGLAALRGEAELDAPHRAQFVDALQRPQPRVALGLALRGLASAMLDVSDGLLGDLRH
                     ILECSGTGAIVEAAALPLAALAASGADAALCRRCLLAGGDDYELLFAAPPRHRGAIEA
                     LSARLGLPLHRIGELTRERERLMLREADGTLAAPAAYGYDHFA"
     gene            complement(18327..18863)
                     /locus_tag="P5537_02905"
     CDS             complement(18327..18863)
                     /locus_tag="P5537_02905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004306779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SCP2 sterol-binding domain-containing protein"
                     /protein_id="HRV77022.1"
                     /translation="MPALPALPRPPLPSELLPGSLRQRIGERLATLRIPDFTVPAPVA
                     KLVARLPQQPPTHVLTLALNLALDRILPRDTLEPLSGRHLQMRVLDAGLTLDFTLGER
                     GFRRATPTAGAKPDLILSATTRDFMALALREEDPDTLFFSRRLRMEGDTDLGLLVKNT
                     LDAVDWDTLKAKLLGRHG"
     gene            complement(18901..19797)
                     /locus_tag="P5537_02910"
     CDS             complement(18901..19797)
                     /locus_tag="P5537_02910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004306781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HRV77023.1"
                     /translation="MKLALGPLLYYWPHQSVLDFYADMAEAPLDSVYLGETVCSRRHE
                     LRLDDWLEVGKVLAAAGKEVVISSQALIESESDLKTLRRIVGQHDFRVEANDMGAVRL
                     LAEAGVDNWIAGPTLNIFNPVTLQLMIDSGATRWAVAPEMSGAALAEVRAALAKPIQT
                     EVFAYGRLPLAHSARCFTARHFNLQKDTCEFRCLSIMDGITLRTREGAPFLTLNGVQT
                     QSARVHNLLGDLPAVHANAEVLRISPQGAHTRQIIELFRAALDGHRSPADALAASREW
                     MVEEPCNGFWHGRAGVEQYVAA"
     gene            complement(19922..20938)
                     /locus_tag="P5537_02915"
     CDS             complement(19922..20938)
                     /locus_tag="P5537_02915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004382723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HRV77024.1"
                     /translation="MSVSSPIELVCPAGSLPALKTAIDHGADCVYLGFKDATNARNFS
                     GLNFDPAQVREGVAYAHARKRKVLLALNTYPQTDNWSSWTQAIDRAAEYGVDAVILAD
                     PGLMAYATKTHPQLRLHLSVQGSATSYEAINWYRERFGIQRAVLPRVLSMAQVESVVA
                     NTPVEIEVFGFGGLCVMVEGRCALSAYATGESPNCNGACSPGKHVRWEDTPRGMETRL
                     NGILIDRFAEGERAGYPTLCKGRFEVNDETYYALEEPTSLNTLELLPELARIGIRAIK
                     IEGRQRSPAYVAQVTKVWRAALDKLNRGGAEAFSVLPAWMAELNKVSEGQSHTLGAYY
                     RPWK"
     gene            complement(21055..22515)
                     /locus_tag="P5537_02920"
     CDS             complement(21055..22515)
                     /locus_tag="P5537_02920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004378848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HRV77025.1"
                     /translation="MLLWLVVAYLVVSIGIGLYAATRVHNARDYITAGRNLPMIVVLA
                     MVFATWFGAETVLGISATFIEEGFSGLISDPLGASACLVLFGLLFARPLYRMNLLTLG
                     DFFRMRYNRTTELVLSICIVLSYLGWVAAQITALGLVFNVLSGDAVTMNQGMLIGAGV
                     VLVYTLFGGMWSVAMTTFVQMIVIVIGLIWVSTIAGDMAGGFDHVVAKAAAEGKFEFL
                     PSLDAVEIIAWIAAFATMALGSIPQQDVFQRVNSSKNETVAIWGTTLGGVSYFFFAAV
                     PLFLAYTANIIDPGMVERLMEQDSQLILPTLILQYMPFYAQVIFFGALLSVIMSTASG
                     TLLAPSVTFSENVLRGFLPGMSDRAFLLSTRMTVVVFTALVTWYATSTESSIHQMVEN
                     AYRITLAGAFVPLAAGLFWKRANNLGAALSIILGLSTWILFELFVPEGDIEPQLYGLA
                     ASALGMLAGGLIGRQPHHRPHIGGHHAAAGTYHTHR"
     gene            complement(22676..24205)
                     /gene="ubiB"
                     /locus_tag="P5537_02925"
     CDS             complement(22676..24205)
                     /gene="ubiB"
                     /locus_tag="P5537_02925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis regulatory protein
                     kinase UbiB"
                     /protein_id="HRV77026.1"
                     /translation="MRLFRLAKIVSVSLRFGLDRMVLDADSSGRLAHVWHKVFFWRSF
                     TESRGARLRQALESLGPIFVKFGQMLSTRRDLLPPDLAEELALLQDRVPPFPTEQALA
                     VLEGFYGKPIDTVFDDFERTPVASASVAQVHFARLPDGTDVAVKVLRPGIERVIEHDL
                     ALLEVAAVLLEKIWPEGRRLKPREVVAEFSKYLHDELDLMREAANCSQLRRNFKDSSL
                     LIVPEVYWDWCGSKVMVMERMRGVPISQTPALLAQGTDLKALSRAGVEIFFTQVFRDG
                     FFHADMHPGNIFVHSDGRYIALDFGIMGTLNEVDKNYLATNFLAFFQRDYRRVALAHI
                     EAGWVPAKTRVDEFEAAIRTVCEPIFDKPLKDISFGKTLLRLFQTARRFEMEVQPQLV
                     LLQKTLLNIEGLGRQLDPELDLWKTAKPFLERWMDERMGVRALVRGIREEAPAWAGTL
                     PQLPRLVHHALTESTRHQSAQQQRLDELAAGQRTQGRLLLIIGAVAIGLLGLELYRLF
                     G"
     gene            24377..26140
                     /gene="argS"
                     /locus_tag="P5537_02930"
     CDS             24377..26140
                     /gene="argS"
                     /locus_tag="P5537_02930"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HRV77027.1"
                     /translation="MSADPKVLLTDLLQTALKSVAPDLAATPILLERPKQASHGDFAT
                     NLALQLAKPLKRNPRELAGLLLAELPPSKLVARAKVAGAGFINFTLASDAKTAVVREV
                     LAKGADFGRGAAKGVKVQVEFVSANPTGPLHVGHGRGAAYGASLSDVLAFAGYEVSRE
                     YYVNDAGRQMDILALSTWLRYLAFFGVEVPFPPNAYQGDYVIDMGRDMRDAHQDRFAR
                     VTLEQVLAGTPGLPPSDRKDDESKQQREEHLDALIANAKKLLGEDYPWVHGFALNEQL
                     GDGREDLQEFGVRFDKWFSEQSLFDTGLVERAVTQLEKAGHIYLQDGARWFRSTAFGD
                     EKDRVVQRENGLYTYFASDIAYHLNKYERGFDRMIDIWGADHHGYIPRVKGAIAALGL
                     PPEKLEVALVQFAVLYRDGQKTSMSTRSGEFVTLRELRREVGNDACRFFYVLRKSDQH
                     LDFDLDLAKSQSNENPVYYVQYAHARVCSVLNQWGGEAAELAAADLGLLHNERELALC
                     ARLASFAELVQNAAADYAPHQVAFYLKDLAADFHSWYNAERMLVEDEAVKLARLALAA
                     AVRQVLVTGLKMLGVSAPESM"
     gene            26157..26825
                     /locus_tag="P5537_02935"
     CDS             26157..26825
                     /locus_tag="P5537_02935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HRV77028.1"
                     /translation="MSRDRRPARKPARAPAKSAGGTLIGIFIGLVFGALIAAGAAWYF
                     TRSNPFQAAPVAPRVQAPAEQGPAALPGKPGDRPVAKQDFEFYRILPQGDNVPSSAAQ
                     VVPVPAPQVQAPPVAVPAQQAPAPVFEASPQPAALAPSPPPRNERIYLQVGSFENPSE
                     ADNLKARLALSGIQASAQRTQLPDGRVVHRVRVGPFAKPEDMNPMRARLSDAGFNASV
                     SRNQ"
     gene            26902..27528
                     /locus_tag="P5537_02940"
     CDS             26902..27528
                     /locus_tag="P5537_02940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004312081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbA/DsbL"
                     /protein_id="HRV77029.1"
                     /translation="MNRRDALKLAGLALALPAASVVQANEPFQIIEPAQKGDDPAKIE
                     VLEFFHYGCPHCRDFHPLITAWKKKLPADVAFRAVPAVWNNAQLSGLARLFYAAQITG
                     ELAALEPAIFAAVQDDKRPLFNEQQVSEWIAGKVGDAAKFIETYKSFGVGSMVQRADQ
                     LARALKIQGVPAMVVGGRYLTSASLTGSHENTLKVADELIARVRKERG"
     gene            27531..27959
                     /locus_tag="P5537_02945"
     CDS             27531..27959
                     /locus_tag="P5537_02945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HRV77030.1"
                     /translation="MSDRDAGALPHAAEAAERRRIQRFLALRRGEPYLWVTIGGERIT
                     LRDISVDGFAIAAATPPAGAAPFDFVLQREGVPDQIRGRAQVVNFIAASGQAGCRFLA
                     LEGDGAERLRDWLVALVIMNASVRISEKDAAAIVAGPSLI"
     gene            complement(28063..30693)
                     /locus_tag="P5537_02950"
     CDS             complement(28063..30693)
                     /locus_tag="P5537_02950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter permease"
                     /protein_id="HRV77031.1"
                     /translation="MTRPDENKDKASFELSDEELKKIVAEADTGGRKPTGLTAQLLLA
                     VALAWSLFQLWIASPLPFSLGVFVFNDTESRAIHLAFAVFLAFAAYPAFKGSPRDHVP
                     VVDWVFAAVGAFCAAYLFIFYRELAQRPGMPTDLDLAAAVAGMLLLLEAARRALGLPM
                     VILAAVFLVYIFFGPYMPEVIAHRGASLAKGMSHMWLTTEGVFGVAVGVSTSFIFLFV
                     LFGALLETAGAGAYFIKSAIALLGHMRGGPAKAAVVASASTGLISGSSIANVVTTGTF
                     TIPLMKSVGYRADKAASVEVASSVNGQLMPPVMGAAAFLMVEYVGISYVQVMKHAILP
                     ALISYIALYYIVHLEALKMDLQGLPRREPLPWQRTLITTLMTVSGLVILSAIIYWGFG
                     WMKTAFGGAAFLVVGVLMLLAYVGLVRFAAQYPELHMEKPDEKMEYLPEIGPTLKAGL
                     HFLLPVAALIWNLMVEQLSPALSAFWATLFLMFILVTQRPLFALFRRTGNIGEAARQG
                     FSDLFTGLITGARNMIGIAIATATAGVIVGTVTLTGIGLAMTELVELLSGGNLMIMLI
                     LVAVICLILGMGLPTTANYIVVSTLMAPVIVELGAQTGLLVPLIAVHLFVFYFGLMAD
                     VTPPVGLASYAAAGIAKSEPMRTGLTAFGYSARTAILPFMFIFNTQILLIGISDTFHL
                     VLTIVSATVASMMFAAATQGFFIAKSRIHENLILLLVTFTLFRPGYWMDMLYPPFEEV
                     PATEFGRLVEEAPRNGNLRVWVEGMSLEGQDISKGVLLPLGEKAGNARERLGAIGLTT
                     MALGDQVQVAAVRFGSQAEKLGLEQGYNIVRIELPSGERPDKEWMYIPAFALIALVWA
                     MQKPRQRRREAERTAGRSRA"
     gene            complement(30806..31774)
                     /locus_tag="P5537_02955"
     CDS             complement(30806..31774)
                     /locus_tag="P5537_02955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TAXI family TRAP transporter solute-binding
                     subunit"
                     /protein_id="HRV77032.1"
                     /translation="MKKLTALAAAFAIAGALGAAPAHAQQKFVTIGTGGVTGVYYAAG
                     GAICRLINKDRAQHGLRCSVESTGGSVYNVNTIKAGELDFGVSQSDIQFNAMKGEAQF
                     KDAGAFTELRSVFGLHPEPLTVLSRKEANIAKMEDFKGKRFNVGNPGSGQRATMGILL
                     PAMGMSDADFSLVSELKPDEHSAALCDNKIDGFAYVVGHPAANIQDPTTTCGAKLVPI
                     TGPAVDKLVADYPYFAKVQIPGGLYANNPNPTDTFGVVASIVTSSKVPAETVYTLVKA
                     VFENFEDFKKLHPAFANLQPQHMIKDGLSAPLHEGAVKYYKEKGWM"
     gene            32052..32891
                     /locus_tag="P5537_02960"
     CDS             32052..32891
                     /locus_tag="P5537_02960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helical backbone metal receptor"
                     /protein_id="HRV77033.1"
                     /translation="MHARTSQDALRTLTDAAGQRHVPAGPDARIVSLVPSLTELVFDL
                     GLGDRLVGRTGFCVHPREALRGVPKVGGTKDVKLERIRELAPTHVLVNMDENRRETVD
                     ALAAFVPDIVVTHPNTPQDNLPLFALLGGVFGAEAAAARLADELRAALAEAAALRATL
                     ADERVLYLIWREPWMTVARDTYIAATLAEVGWYTVPAVEGGETGAARYPAFDWEAPWL
                     ADVARVLLSTEPYRFRAEHLPEVESLARRPALLVDGEMVSWYGSRAARGLRWLMALRR
                     GMA"
     gene            complement(32901..33377)
                     /locus_tag="P5537_02965"
     CDS             complement(32901..33377)
                     /locus_tag="P5537_02965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004312075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN domain-containing protein"
                     /protein_id="HRV77034.1"
                     /translation="MTEPSSQAALLPTLVLDTNTVLALWMFRDPALETLRAWIDAGSC
                     RLVSRADALEELRRVLAYAQFGLDPDRQDGLRTRYLARIAVLANDADAGTLPGCRDPD
                     DQKFLEIAGAAGMATLITRDKALLRLARHRLVRERFAILTPERMQQTLAQPDEKPT"
     gene            complement(33475..35298)
                     /gene="phaC"
                     /locus_tag="P5537_02970"
     CDS             complement(33475..35298)
                     /gene="phaC"
                     /locus_tag="P5537_02970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0042619 - poly-hydroxybutyrate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I poly(R)-hydroxyalkanoic acid synthase"
                     /protein_id="HRV77035.1"
                     /translation="MAAPSNETPACDLPDPQEVAKTYAEVARRASHLISDHVHRQLKK
                     GVSAPADELGIAQAFMDMMAKLLANPYKLAQAQMNLVWDYFSLWQHSMMRVAGLSAAP
                     VAAPEKSDKRFKDEEWEQHFLFDFIKQSYLIAARHIHDTVSGVDGLDEQTQKKVTFYT
                     RQYIDALSPSNFAMTNPEVFRETVKSHGQNLLKGLNNLLRDVEDGGGNLRVKMTDTSA
                     FELGKNVATTPGKVVFQTDMMQLLQYTPSTDKVLKKPLLIVPPWINKFYILDLREKNS
                     YIKWAVDQGHTVFVISWVNPDERLAQKSFDAYVKEGVVAALDAIERQTGEKEVNAAGY
                     CLGGTLLATTLAYLAAKRQKRIASATFFTTMTDFTDPGELGVFIDEGQVSSLEKKMFE
                     RGYLEGSEMAGTFNMLRANDLIWSFVVNNYLLGKDPFPFDLLYWNSDSTRMPAAMHSF
                     YLRAMYMENRLIEAGGVEIDGTPIDLSKIKVPCYFISTIEDHIAPWKSTYMGARRFGG
                     PTRFVLGGSGHIAGIVNPPAANKYGYWLNPAAKLADTADAWLEGAQQHPGSWWTDWQA
                     WVTAHDGEQTEARDPVKGKLEVLEDAPGSFVKIRIDAKAAA"
     gene            complement(35347..36381)
                     /locus_tag="P5537_02975"
     CDS             complement(35347..36381)
                     /locus_tag="P5537_02975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HRV77036.1"
                     /translation="MSTASPTPLEYPFDSLPAPGHTIEIAPGLRWVRMRLPFALDHIN
                     LWLLDDGEALAAVDCGFAREETREAWNAVLAADGRPLRRVVVTHHHPDHIGLATWLAA
                     RDDAAIHMTQGEFFAAQAVWHQLPGYCATDMVEQFRRHGLDDMRRDALLTRGNAYRVG
                     APQVPGRYERMFAGDELRIGAHSWRVIVGFGHAPEHASLYCAELGVLIAGDMLLPRIS
                     TNVSVYAATPHGDALGWFLHSLREFCTLPDDTLVLPSHGKPFKGIRARVEQLVEHHRE
                     RCEVLLAACAMPQSAAALLPTLFPRELDTHQVMFAMGEAIAHLNHLEKTGTLSRRVDA
                     DGLIRFTHCS"
     gene            36534..37001
                     /locus_tag="P5537_02980"
     CDS             36534..37001
                     /locus_tag="P5537_02980"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047617 - acyl-CoA hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HRV77037.1"
                     /translation="MRPEAPQFQPRDPGYAERVRASFALQQAMSLIGAELPVVEPGYT
                     EIHLPFKAEISQQHGFIHGGVVGMIADSAAGYAANTLTPADTSVLTVEYKLNLVAPAD
                     GERLVARGEVVKPGRTLIITKAEVFAIREGKWTLCALMQQTIMAMHGKKERAA"
     gene            37061..38203
                     /gene="can"
                     /locus_tag="P5537_02985"
     CDS             37061..38203
                     /gene="can"
                     /locus_tag="P5537_02985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004312071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004089 - carbonate dehydratase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbonate dehydratase"
                     /protein_id="HRV77038.1"
                     /translation="MPSRLCALGADDTTELEHVRGFFRQYAAWLGVDLSFQGFADEIA
                     NLPGAYGAADGRLFYAEVDGQPAGCVGIRRFSEGVCEMKRLYVDPAFRGRGVGRKLAL
                     AAIKAAHLFGYRRILLDTVPSMRIAVKLYRELGFKEVPAYYPSPIEGTIFLTLDLENW
                     SEDEVNNENLFHLFDYNQAWSRQMQQIDPGFFGKLAQLQAPEYLWIGCSDSRVPANQI
                     VGLLPGEVFVHRNIANVVVHTDLNALAVIQYAVDVLQVKHVMVVGHYGCGGVKAALER
                     TRVGLTDLWLRHVQDVHARHLQAVDSLAPERRYDRLCELNVIEQVANVAQTVVVQDAW
                     RRGQRLTVHGWIYGLQDGLIRDLGMNVSRPDDLMPRYVAALEALGS"
     gene            38259..39467
                     /locus_tag="P5537_02990"
     CDS             38259..39467
                     /locus_tag="P5537_02990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HRV77039.1"
                     /translation="MSDPVVIVSVARTPLGGFQGDLSSLTTPQLGSTAIKAAVERAGL
                     APEQVQEVIMGCVLPAGLGQAPARQAALGAGLPLSAGCTTINKVCGSGMKATMLAHDL
                     ILAGSNEVMVAGGMESMSNAPYLLPKARAGYRLGHGQMFDHMFLDGLEDSYSKDHKGR
                     LMGTFAEDCASHFGFSREAQDEFAIASTTRAQAAINNGDFIWEVVPVTVSGRKGDVVV
                     DKDEQPLKAQIEKIPTLKPAFRKDGTVTPANSSSISDGAAALVLMRKSTADRLGLKPV
                     ATILGHATHAQEPHWFTTAPVGAMQKVLAKAGWTTGDVDLWEINEAFAVVTMAAMHEM
                     KLPHDKVNVNGGACALGHPIGASGARILVSLIGALRKRGLKRGVASLCIGGGEATAMA
                     IEVDASVACG"
     gene            39548..40681
                     /locus_tag="P5537_02995"
     CDS             39548..40681
                     /locus_tag="P5537_02995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HRV77040.1"
                     /translation="MILTQEQELIRDSMRAFAQERLAPFAAEWDRNHTFPREALNELA
                     ELGALGMVVPEEWGGAGMDYMSLVLTLEEIAAGDGATSTIVSVQNSLPCGILNRFGSD
                     AQKEAWLKPLARGEKLGCFCLTEPHVGSDASAIRTSAVRDGDEWVLNGVKQFITTGKH
                     ADVAIVFAVTDKAAGKKGITCFLVPASAPGYQVGRIEEKMGQKASDTTQILFEDCRIP
                     ADSVVGAEGEGYKIALSNLEAGRIGIAAQCLGMARAALEAAVKYAQERESFGKPIFEH
                     QAVNFRLADMATQLEAARQLVWHAASLKDAGRPCLKEASMAKLFASEMAERVCSDAIQ
                     VHGGYGYVTDFPVERIYRDVRVCQIYEGASDIQKLVIGRALAG"
     gene            40971..41378
                     /locus_tag="P5537_03000"
     CDS             40971..41378
                     /locus_tag="P5537_03000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004312068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77041.1"
                     /translation="MNSVTRELMRPAEPRPAQAAEREQAARAQEPAARDAAASQAAQP
                     SAVVTLSAAARAEGAAQPAPPAQDGTVEARAVEQARAAAANGDVRNNYSAQRALASYE
                     AMSQVGANNAAARPSQPEQAVAPGQREPGVLRT"
     gene            41462..41926
                     /locus_tag="P5537_03005"
     CDS             41462..41926
                     /locus_tag="P5537_03005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77042.1"
                     /translation="MSIQGLGSSASAASWLGGQVSREQARRSAEQLDAKAAALAAEAA
                     SARDEADTAQRRADELQTQAGQARTRAELGKQAVASVRGMDRAAQAVSAAVGRVGEAV
                     AAEPAQGASAPAAAGVRAGESAGAQSAGLYTAAAGIRPALSVQPGQLVDLKV"
     gene            complement(41964..42548)
                     /locus_tag="P5537_03010"
     CDS             complement(41964..42548)
                     /locus_tag="P5537_03010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004312066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2889 domain-containing protein"
                     /protein_id="HRV77043.1"
                     /translation="MLGSSERERVHTRRIVCEAFRRRDGLWEIEATVIDEKGEDMPFR
                     SRPMVRPGQSLHDITIAVLIDDDAMIHDVAARMQTVPWAACPESQAAYRRLVGLQIGA
                     GFMREVRERVGGVQGCTHLTDLLVQVGNTYTQAIWPTLIARQFAAEPDPRKWTDRRAV
                     GFVGGCAAWRQGGDTLRQEYPELAEEFAAKHDGG"
     gene            42655..43080
                     /locus_tag="P5537_03015"
     CDS             42655..43080
                     /locus_tag="P5537_03015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HRV77044.1"
                     /translation="MDVEQFMQGYKKAWEERDEAQFCALFATDGEYHNTPFAVQRGHA
                     QLAAYWQRVKLQEDVQVRYEILASAPAGGVAHWHVTYQVASEELFRIWAQSTGTNLVA
                     RKPGDPLPRMVLDGVLKAEFDGDLCRRCDIWWHSMPMQA"
     gene            complement(43180..43848)
                     /locus_tag="P5537_03020"
     CDS             complement(43180..43848)
                     /locus_tag="P5537_03020"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-CTERM sorting domain-containing protein"
                     /protein_id="HRV77045.1"
                     /translation="MSRTRQFLSGLKPLALCVGVLASASSSAALFKGVEFPGGAASFA
                     DAVVSYTPSFGGGNVPTAPYQDSSQALGVPNYPEGQDPEYVSLGAGGRIVLRFTDNSL
                     TGSGNNALDLWIFEIGPDVEDTFVDISKDGSTWYGVGKVFGATSGIDIDAFGFGLTDF
                     FSFVRLTDDLNEGDKAGVTVGADIDAVGAISSAPPVTIPEPGALALLGIGLLGIAARR
                     RRAC"
     gene            complement(44028..44525)
                     /locus_tag="P5537_03025"
     CDS             complement(44028..44525)
                     /locus_tag="P5537_03025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77046.1"
                     /translation="MTTALHVASLLLCATLLTTPAHADTVDCSGRMGHVSIDGDLRVP
                     SGKTCTLDGTRIEGNVVVGRAATLSARGVRIEGKLQAEDARQISMVASSRVGDNIQLE
                     RSGAVRLDSVTVGGDVQLFANHGALRIAHNRVDGNLQCKSNQRRPTGGGNRVRGNKED
                     QCARP"
     gene            44742..45107
                     /locus_tag="P5537_03030"
     CDS             44742..45107
                     /locus_tag="P5537_03030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004294546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HRV77047.1"
                     /translation="MHKTLATFSDLNTPPVFDFPRPERLVAGNPQRATWTRFERDGMS
                     AGLWGCEPGAWRIAFADDTDEFFHVLSGRIRITDEAGLAREFGAGEACVIPAGFKGVF
                     EVLETVMKHYVFVKRGDMR"
     gene            complement(45156..46226)
                     /locus_tag="P5537_03035"
     CDS             complement(45156..46226)
                     /locus_tag="P5537_03035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004265427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HRV77048.1"
                     /translation="MAKIYLSSTYKDLAEARAAVYRVLRKMGHDVVAMEDYVSSDQRP
                     LDQCLADVAASDLYIGLFAWSYGYIPPQQERSITELEFRQAERCRKPCLLFLLHEDAP
                     WSRKLMDRDLERIESLRTELCRDRVVSFFRTTDELAAAVSVAVARQQSEGTQGTSSAR
                     GEADALVELVGRMVGECIRLVEQRQHSDQRLYEDFVGPALDDFEKVHQNYLECFQRYR
                     GLVEDANVPLDGDHPVLKKIGEDMLFWAQLRLKLDALQDFRKDPLFGSFITRIVEYTR
                     GSEFMRKVLLDGARPLPNAARGCALVGLGAIFAGEQPTAAKRTEALNLLDRVVGDLQV
                     AYGQVLREHMALKKRLLDHREG"
     gene            complement(46386..46868)
                     /locus_tag="P5537_03040"
     CDS             complement(46386..46868)
                     /locus_tag="P5537_03040"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047617 - acyl-CoA hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HRV77049.1"
                     /translation="MDLPAHQLTMTVLMTPDTANFSGKVHGGAILKLLDQVAYACASR
                     YAGHYVVTLSVDQVMFRQPIQVGELVTFLASVNHTGNSSMEVGIKVVAEDIRAKVVRH
                     VNSCFFTMIAVDDEGRPTKVPALSPQTPDERRRFAAAEVRRAMRREMERKFAAVHAGE
                     "
     gene            complement(47084..48130)
                     /locus_tag="P5537_03045"
     CDS             complement(47084..48130)
                     /locus_tag="P5537_03045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HRV77050.1"
                     /translation="MKILAPSPAELTRGRAATPIAFIRAIAAGYRLRGMDPARALAQA
                     QIPPALLDDPAARVTAAQMELLSGLAMQELDDEALGWFSRRLPWGSYGMLCRASLSSP
                     TLEVALKRWCRHHRLLTEDIVFELAQRGGTATIRVAEHAELGELREFCLVSTLRYLLG
                     YACWLVDSRIALGEAAFPFPAPAHADAYTYLFTGPARFSAATAGIRFDARYLALPVRR
                     DEKALQAMLQRALPLTVLQYRRDRLLVHSVGQVLAANPAAAHTAEEVAAQLNLSVRTL
                     HRQLKEEGVSLQRLKNAARREHAVKLLLQTTKPVKQIAAAVGFDSEKSFARAFREWAG
                     VTPSAYRMGAGLAP"
     gene            48306..49487
                     /locus_tag="P5537_03050"
     CDS             48306..49487
                     /locus_tag="P5537_03050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isovaleryl-CoA dehydrogenase"
                     /protein_id="HRV77051.1"
                     /translation="MNVPSLNFNLGETIDALRDTLQAFCAAEIAPRAAEIDRTNEFPA
                     DLWKKLGDLGVHGMTVSEEYGGTDMGYLAHIVAMEEISRASASVGLSYGAHSNLCINQ
                     IRRNGTEAQKQKYLPKLISGEHVGALAMSEPNAGSDVVSMKLRADRKGDRFILNGSKM
                     WITNGGDADTLVVYAKTDVAAGPKGITAFIIEKGMKGFSHGTHLDKLGMRGSNTFPLF
                     FDDVEVPVENVLGGEANIGRGVQVLMSGLDYERAVLSGGPLGIMAACMDVVVPYMHER
                     KQFDTPIGEFQLMQGKIADLYSTWSACRAYAYAVGQACDRADHARTLRKDAAGVILYT
                     AEKATWMAGEAIQALGGVGYTNEYATGRLWRDAKLYEIGAGTSEIRRMLIGRELFSET
                     R"
     gene            49502..51109
                     /locus_tag="P5537_03055"
     CDS             49502..51109
                     /locus_tag="P5537_03055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxyl transferase domain-containing protein"
                     /protein_id="HRV77052.1"
                     /translation="MSVIKSGINTRSADFQSNAAAMRGLVGDLRAKAAEVSLGGGEAA
                     RAKHTARGKLLPRDRVGHLLDPGTAFLEIGQMAAYGMYDNDAPSAGVIAGIGRVQGIE
                     CMIVANDATVKGGSYFPMTVKKHLRAQEIAQANRLPCIYLVDSGGANLPTQDEVFPDR
                     DHFGRIFFNQANMSAQGIPQIAVVMGSCTAGGAYVPAMSDEAVIVKNQGTIFLGGPPL
                     VKAATGEVVSAEDLGGGDVHTRISGVADYLAENDSHALHIARRIVSNLNQRKEVELAL
                     ADSEEPAYDPEEIYGIIPADPRKPYDVREVIARVVDGSRFDEFKPRYGTTLVTGFARL
                     YGYPVGIVANNGILFGESAQKGAHFVELCGQRGIPLLFLQNITGFMVGRKYENGGIAK
                     DGAKMVTAVATVQVPKITMIMGGSFGAGNYGMCGRAYSPRFLWMWPNARVSVMGGEQA
                     ASVLSTVRRDGIEAKGGTWSKEDEEAFKAPIREQYEVQGHPYYATARLWDDGVIDPAQ
                     SRRVLGLSLSATLNAPIPQTKFGVFRM"
     gene            51165..51527
                     /locus_tag="P5537_03060"
     CDS             51165..51527
                     /locus_tag="P5537_03060"
                     /inference="COORDINATES: protein motif:HMM:NF014643.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HRV77053.1"
                     /translation="MISIADAKNRLPALIHQAEAGEPVTITRRGKPVAVVLAVQEYER
                     MRVATTARPSFWDVVQEVRAKLAAEDAFPDWTDEEIDSWRDRTIYEPRCDFSGPEYDW
                     AGGVADDSEGPDVKQERA"
     gene            51527..51961
                     /locus_tag="P5537_03065"
     CDS             51527..51961
                     /locus_tag="P5537_03065"
                     /inference="COORDINATES: protein motif:HMM:NF013970.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family
                     toxin"
                     /protein_id="HRV77054.1"
                     /translation="MGVSVLLDTNVLSELLKPRVDPGVVRRFSRDGNDCAIASVVWHE
                     LLCGALRAPSVGRGEMLVRACRDIVIGSGMQILPYDETAATWHARERARLLGLGRPQP
                     YPDCQIAAIAATRNLTLVTRNTRDFECFDGLRLENWFEAGKD"
     gene            51988..52776
                     /locus_tag="P5537_03070"
     CDS             51988..52776
                     /locus_tag="P5537_03070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011766794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HRV77055.1"
                     /translation="MYETLEIQRKAGVATIWMNRPDVHNAFNAQLIADLTTACIELDA
                     DDAVRAVVLAGRGKSFSAGADLNWMKAAGEASEAENFADAMKLAGMLRTLAEMKKPTI
                     ARVHGAALGGGMGLASACDICIAGDKAVFATSEVKFGIIPSAISPYVIRAIGERQSYR
                     YFQTAERIGAARAAELGLAHEAVATDELDAKVSEVVEALLQGGPKSQAAAKDLIRAVA
                     NRPVSDAVVEDTARRIASLRATPEAKEGLAAFLDKRPAAWIAQG"
     gene            52845..>53404
                     /locus_tag="P5537_03075"
     CDS             52845..>53404
                     /locus_tag="P5537_03075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004291847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4126 domain-containing protein"
                     /protein_id="HRV77056.1"
                     /translation="MDAYAWSSWPTELTALLDWSGVPLDMASLAALAAGLGWASGLRL
                     YALVFVLGALGRFGGVQLPGGLEVLTHPLLLGVSGVMLLAEFFADKLPWFDSMWDAVH
                     TFIRIPAGAALAAAVMGDQAGAVQLAAALAGGTLAAGAHFAKAGARAAINTSPEPVSN
                     VTTSLGEDAMFAGGLWMLLQEPLWFLV"
BASE COUNT         8078 a        17729 c        19384 g         8213 t
ORIGIN      
        1 cgcacaccat cacggtgtcg ccgtcgccga tcatgttgta gtcgccgatg gcctcgccga
       61 cgccgcgctc gagcttcttc ttgaggcgca ggaaggtgtt ggagaagcgg gcgtctgcgc
      121 cggcctcggt ggcggggagg gtggcggcgc ttgcgggggc tgcggtcacg atcggtgctc
      181 gtcgggaaaa tcaggcgtga attatcccag aaaccggcgc ggaaacggct ctcgcctaga
      241 ggtgcgcgct gcgcccgccg tccacggcga tgatctggcc ggtgacgtag ggcgcgtcga
      301 acatcaggaa ggccaccgtg cgcgcgatgt cgtccgggct gccgacgcgg ccgagcaggg
      361 tgtgggcgac gatgcgctcg cgctcggcgg gcgggaactg ctcgtcctcc ggccattcga
      421 tcggcccggg cgagacgccg ttgacccgca ccgcgggggc gagctcgatc gcgagcgaac
      481 gcgtcagcgc cgccagtccg gccttggccg cgcagtacac cggatagccg gcgagcgggc
      541 gctgggcgtg gatgtccacg atgttgacga ttgcgccgcg cgcctcgcgc agcgcgggtg
      601 caagcgcctg ggtgaggaag agcggaccca tcaggttgga gcccatgagc tcgtcccagg
      661 ctgcgcggtc gatgctgccg agcggcgtgg ggaagaagct ggaggcgttg ttcaccaggc
      721 cgtcgaggcg gccgccgcgc gccagcaccg ccgcggcgat ctcggcggcg gcgccgaagc
      781 gcgcgaggtc gccgcccacg gtgaaggcgg attcggcgcg cagcgcgcac agctcggcgg
      841 cgagcccctc ggcctcggcg gcgctgtggc ggtagtgcag ggcgaggcgg gcgccgccgg
      901 cgtgcagccg gcgcgcgatc gccgcgccga cgcggcgcgc ggcgccggtc accaggatca
      961 gcggtgccgc ggcgggttcg gattcggttg cggagtggag ctcgaaggga ggcgtgtgca
     1021 tcggattcac cgtgaggccc ggcgccggcc gggcggctgg gcgggcgtgc cgctacaatc
     1081 gcggcctcgc ccaactgtcc cgcagaacga tcatgtcttc attgccccag ccttccgccg
     1141 atgcgctcgc ccagagcgcc cgcctgctcg aaaccatcga ggccgagctg gccgcggccg
     1201 gcggctggat cccgttcgcg cgctacatgg agctcgcgct ctatgcgccg ggactggggt
     1261 attacagcgg tggcgcacga aagttcggcc ccggcggcga tttcatcact gcgcccgagc
     1321 ttaccccgct tttcggccag gcgctcgccg cccaggtcga gcaggtgatg cgtgccagcg
     1381 cacccgcgct gatcgaggtc ggcgccggca ccggcctgct cgccgccgac ctgctgctcg
     1441 agctcgagcg ccgcgactgc ctgcccgagt cctacggcat cctcgagctc tcgggcgagc
     1501 tgcgcgagcg ccagttcgat accctggccg cgaaggcgcc ccacctggcg gcgcgcgtgc
     1561 agtggctgga cgcgctgccg gagcgcttcg ccggtgcggt ggtggccaac gaggtgctcg
     1621 acgtgatgcc ggtgcatctg gtggtgtcgc gcgccgaggg gctcttcgag cgcggcgtgg
     1681 cgatcgccgc cgacgcggcc ggggcgcgcc ggctgtgctg ggcggacgtg ccggcggcgg
     1741 gcgcggtggc cgaggcggcg ctggcgctcg cgctgccggt gccgcagagc ggcgaatacg
     1801 tcaccgagct caacctcgcc ggcaaggcct gggtggcggc ctgggccgag cgcctgcagg
     1861 cgggcgccct gctgctgatc gactacggct atccgcgcgc cgagtactac ctgccctcgc
     1921 gctcgggcgg caccctgctg tgctactacc gccaccacgc ccacggcgac cccttcctgt
     1981 ggccggggct caacgacatc accgccttcg tggactttac cgcggtggcg gaggccggct
     2041 tcgaggccgg gctggacgtg cagggctaca ccacgcaggc gcagttcctc ttcaactgcg
     2101 gcgtgctcga atgcctggag cggcgcggcg cgcgcgagag cgcggactac atccgcgccg
     2161 cgcgcgccgt gcagcgcctg accgcgccgc aggagatggg cgagctcttc aaggtgatcg
     2221 cgctcgcgcg cgcgatcgac gggccgctgc tgggcttcgc gcgcggcgac cgcacgcacg
     2281 ccctctgagg cggcgcagcg tcgcctacag cgcgcgctcg gccagccagt cggcgatccg
     2341 catcgcgccg agctcccagt cgcgctcgag catcatgccg tggcccatgc cggggaggat
     2401 ctcggcctgg cggccgtagg tcatggcggt catgtgcacc tggtcgggcg ggatcagggc
     2461 gtcgtgctcg gcgcccagga tcagcatcgg cacgcggtgc atgcgtgcag gctgcggcag
     2521 gttgaacagt gacatgtccc agatcgcgcg gtgcgactcg ggttggctca ggcggtagta
     2581 gcgctgcagg tcgtcggccg ccaccggctg gtggaagagc gcctcgcgca ggctgtcgat
     2641 gtccacgtca ttgccggaca tgatgcggtt gaggtccgag agcaggtgcg ggcgcttgaa
     2701 catgaggccg aaggccgagc ccatcaggcc ctgcggcggt accgcggaca tcagcaccgc
     2761 ggcgggggcg tcgtgttgct cgagatactt ctgcaccacc atcccgccca tcgagtgtcc
     2821 gaccagcaca ggcggagccg gcaggcgggc ggcgacctcg gcgacgtcgc gcacgtagtc
     2881 gtcgagcgag taggagtcga ggtgctcgcg ctggcggctg cggccgtggc cggagagcga
     2941 gacggcgtag gcttgccagc cgcggcgggc gaaccagggc aggaagtgtt cttcccagca
     3001 ccacgccgag acgtaggcgc cgtggatgaa gagcagggga tgttcatggg tggcgcgctc
     3061 gggtgcgtgg cacagcacct cgagttcgcc gaagcgggtt gcgttcatgc ggggtccttg
     3121 tccagggcct tcacggcggc cacgcgggcg gcgtgcaagg cctgaggaat cagcgatttg
     3181 tcgctgcact cggttgcgat tctaccggca tcgacggcgc gcacggcctg cagcgcggcc
     3241 tgccagcgtg acaggggtct ccattccgat gcgttttccg tgccgtcgcc gcgaccggcg
     3301 tgatcgcagg cggcggcctg cagcatcagg aggaagcgct gcggacggcg caggccgtcg
     3361 cagcgctcga tcagcttgac catggtctcg gcgcgcagct cggcggcgcg cgccaggatg
     3421 ccgtgctcgc gcgccaccag ctcggcgagg tcgcggcagt cggcgggggc cttcaggcgc
     3481 tcggacacct cgcgcgcgcg gcgtgcgctc gcggcttcgt ggccgtaatg gtgcggcaat
     3541 gcatgcgctg gcgtgtcgcc cttgccgagg tcgtggagca ggcaggccca gcgcaccgcg
     3601 agcggctcgc ccgcggcggc ggcgtggtcg atcaccatca gcacgtgctc gccggtgtcg
     3661 atctcggggt ggtgctgctc gggctggggc acgccgaaca ggcggtcgag ctcgggcagc
     3721 aggcgcgcga gcgcgccgca ggcgcgcagc acgcggatca tgcgcgcggg gcgcgcctcc
     3781 atgagcccgc gcgcgagctc ctgccagacg cgttcggcga ccaggtggtc gacttcgccg
     3841 gccgcgacca tggcgcgcat cagcgccagc gtctcgggcg ccagctcgaa gtcggtgaag
     3901 cgggccgaaa agcgcgccac gcgcaggatg cgcagcgggt cctcggcgaa ggcgggcgag
     3961 acgtggcgga agacgcgcgc ggcgaggtcg cggcggccgc cgtaggggtc gatcaggcgg
     4021 ccgtcctcgg cgcgcgcgat cgcgttgatg gtgaggtcgc ggcgctgcag gtcttcctcg
     4081 agcgtgacct cgggcgaggc gtggcagacg aagccggtgt agccgtggcc cgacttgcgc
     4141 tcggtgcgcg cgagcgcgta ttcctcgttg gtatgcggat gcaggaagac cgggaaatcg
     4201 cgcccgaccg ggcggaagcc gcgcgcgagc atctcgtcgg gcgtgctgcc gaccaccacc
     4261 cagtcgcgat ccttcaccgg taggccgagc agggcgtcgc gcaccgctcc gcccacgaca
     4321 taggcctgca tcagccgtag aggtcctctt ccgggatcga ctcggtctcg gcgcgcgccg
     4381 ccgccgccca ctcctgcatg tgcgggttgg cgagcagggt ggcgaggtat tcgccggccg
     4441 cgccctcggg cttcaccgcg taggtctgga agcggaaggc caccggcgcg aaggcggcgt
     4501 cggcgaggct gaagcggccg aagaggtagg gaccctcggc gccgaagcgc gcgcggcagt
     4561 cgttccagat cgccacgatg cgcgcgatgt cggcatcgac ctcggggctg tggccgaagc
     4621 cggtgtagtc cttgcgcacg ttcatcggca tgcggctgcg caggttctgg aagccggagt
     4681 gcatctcggc ggtcaccgaa cgcgccatcg cgcgcgcgac cgggtcgccc ggcagcaggc
     4741 ccgggcgctt ctcggcgagg tattcaccga tcgcgagcga gtcccacacc accgcgccgt
     4801 ggtcgttcag gcagggtacc ttgcccgagg gcgagtgcga caggatgcgg tcgcggctgc
     4861 ccgggatgaa cagcgggatg cggatctcct cgaaggtgaa gccgccctcg cgcgccgcca
     4921 gccaggcgcg cagggaccag gaggaatagt tcttgttgcc gatgatcagc ttcatcgcgg
     4981 gctccgtgga gggttgtgct tcagcgtcgc gcgtggcggc ggaaggggta gtagtgggcg
     5041 cgcggcgcgg cctggccgag ccaggccggg gccacggtct cgagcgcggt cgggatcatg
     5101 ccgaagggct gcgggctgcc ggtggcgacg ttgtcgacct tcatcgagcg cacgttgtcg
     5161 cggctcatca gcggctgggg cgcgagctcc atcatgcgtg cctgcaacat cgcgagcttc
     5221 tcggacagcg gatagatcgg gcgcggcttg ccgaccagcg cggagacgta ctcgacgagc
     5281 tggcgcagcg tgtagaccgt ggggccggcg agctggaagg tctgcccggc ggcgtcgtcg
     5341 cggatcaggc tctgccacac cgcctcggcg acgtcctcga catacaccgg ctggaagcgc
     5401 gtgccggcgc cggccagcgg cagcaccggg aacatgcgcg cgaggtcggc gaagaggttg
     5461 aggaagctgt ctccgcggcc gaacaccacc gagggctgca ggatggtcca gccgatctcg
     5521 ggcgagccgg tgcgtatcgc ggtctctccg gccgctttcg agcgctggta ttcggagggg
     5581 ccgtcggagt aggcgccgag cgcgctgata tgcaccaggc gcggcacgct cgccttgcga
     5641 caggcggcga cgatcttctg cggcagctcg acgtgggcgc gcgcgaagtc ggggccgaag
     5701 ggcttgccgg ggcgcgagtg caggacgccg acggtgttca ccaccgcgtc ggcgccctcg
     5761 aacaggcgtg cgagcagggc gacatcgtgc acgttgccct ccaccacctc gacgttgggc
     5821 agcagcagca cgtggccggc gcggctgcgg cggcgggtgg gaatgaggac cttgacgcct
     5881 tccttgcaga ggcgattggc gatggcgctg ccgataaagc cggagccgcc gacgatgacg
     5941 acacgtttcg ggttcatgtt tcgactggac cgtgctgttg ctgtggttgg aatgggatgc
     6001 cgcacccgga agcttactcg ctggccgccc cgggcgcgat cgtgccgagc cgcgccttga
     6061 gcgattgcgg ttgtttttcg agcatcgccg agtagatcac cgcgttggcg agcaccttct
     6121 tgacgtagtc gcgggtctcg tcgaaaggga tcgtctcggt gtagatcgcg ccctcgagcg
     6181 gcgccgcgtc gcgccagcgc cgcgcgcgcc cggggccggc gttgtagccg gcgctggcga
     6241 gcacggggtg ggcgtcgagc ccctccatga tcaggcgcat gtagctggtg ccgagcagca
     6301 cgttggtctc ggggtcggtg agcaggcgct ggctgtagcc gacgaggccg atgcggtcgg
     6361 ccacccactt gccggtggcg ggcatgacct gcatgaggcc ctgggcgccg acgctggagc
     6421 gcgccgggac cacgaagcgg ctttcctggc gcatgaggcc gtacacccag ccgaggtcga
     6481 gcccctgtgc gcgcacctgg ggttcgacca ggtcgcggta gggcgtcagg aagcgcagct
     6541 cgaagttgct gcgcggattg gccagctcgg cggtgttgat cgcgcgatcg tagagctcgt
     6601 tgcgcagcgc gaggtgggcg gcggcgaggc ggaactgctc gtcgcgctcg cgcacgcccc
     6661 acacccactc gcgcagcgcc tcggcgcgca ggtcgaggcg gtagagcgcg agcgcgcgct
     6721 gcagcccggg gtcgcgctcg gcctcctcga gcttggcgcg tggcagcggc gcgctggcgg
     6781 ggggcggcgg gaaggcctcg ccgagctcct cgcgcgcgag catgccgtag aagtgcggct
     6841 cgccggcgat gcgcacgtag accgattcgg cggcgtcacg acggccggcc gcggcgtggg
     6901 cgcggcccag ccagtagatc cagtcggggg cttcgcgctc ttcggcaggc atggcctcga
     6961 tcgccgcgcg caccgcttgc cagtcgccga tgcgcagcgc cgcccgcacc cgccaggcgc
     7021 gctgctgggc ggtggtctcg atgtcgccgg cggcggcgta gagcgcgctc gcctcgggca
     7081 ggcggtcgag cgcggcgtgc atgccgagcg ccaggtgggc gtagttgcgt tcgggggcgc
     7141 cgaggcggtc ctggatgcgc agcaggcgca ggcgtgcggc ggcgacgtcc tcgcgcgcga
     7201 ggcgcacgag cgcggcgagc gcgagctcgc ggccggcgcg cgtcaccgcg aagttgggcg
     7261 gcaggcggtc gagccagggt gcaggcgagc ggatcgcctg cccgaggtcg gtggcggcgg
     7321 gcgcgctggc tgcgggcagc agggcgaggc tggcgagcgc ggcctcgggc ttgcgggtat
     7381 cgatctggcg acggatccgc caccacacgc gctcctcgtc caccgcgccg gcatcgaccg
     7441 ccgcacgcag cggcgtgtcg caggccgcgt cggcgtcggc aagcgtgtcc cactcgcgcg
     7501 cgagctcggc gaggacgctg cgatcaccgc tcagcacgcg cgcgctccag gcgttgcagc
     7561 gcagctcggc gtcggggttg cgcaggtcgg cgtatgcgtc gaggaagccg cgccagtcgc
     7621 cgtcccttgc caggcggcgc agccactcgg cgcgcaggcg ttcgccgagg ttggagcccg
     7681 cttcctcggc gaggaaggcc tgcacggccg cgaccggcac gggttcgtcg gcgcgtgcga
     7741 ggcggttgat cagcagccag tagcgcggat aagcgtcgag ggggtgggct tcgcgcacgg
     7801 cggcgaggcg ttccagcgtg gcgcggtcgc ccttgcgcag ggcctcgcga gcggcgacga
     7861 tacgttcgtc gcccgactcg tcgccgacct gcgcgaacgc gctggcgggg gcgagtaacg
     7921 tcgcggcggt gagtgccgca accaatgcct tcttcatgcc agatgatgcc tccgtgtgac
     7981 tggcaaccat accatatcaa agatgacttc cgcccccttg ccccatgaac ccggcgcgcg
     8041 tcgcaagcgc atgcgcgagc atgcgctgga actgcgcgag cgcctgcccg ccgagcgccg
     8101 tgagcgcctc tccgccgcga tcggcgggca tctcgacacg ctggtcggac ggctgcggcc
     8161 gagccggctc gccttctgct ggccctaccg cgccgagccc gacctacgcc cctgggtgca
     8221 ggcctggctc gcggctgcgc ccgggcgggt ggcggccttg ccggtggtgc tcgagcgcca
     8281 tgcgccgatg gtgttccgcg cgtggacgcc aggcgtgccg atgccgctcg accgccatgg
     8341 catcccgcac cccgcggacg gcgaggcggt cgaaccggag ctggtgctga tcccgctcaa
     8401 tgccttcgac gatcgcggct accgcctcgg ttacggcggg ggctacttcg accgcaccct
     8461 ggcggtgatg cgcaccgtgg cggtgggcgt gggcttcgag atcgggcgcg tgcccgacac
     8521 gctgccgcag cagttcgatc gcccgatgga ctggctggtg accgaggcgg gggtggcgaa
     8581 gccgcgcgcg tgagcgccga ctccagcctg tccgtggcag cgcgcgagct cagctgccgg
     8641 acaggaacat gcggtaggcg gggttgtccg tctcggccac gtagtcgtag ccgacgcgct
     8701 gcaggaaggc gtcgaaggcc tccttgtccg ccggcgggac ctgcatgccg accagtacgc
     8761 ggccgaagtc ggagccgtgg ttgcggtagt ggaacagcga gatgttccag tccgagcgca
     8821 ggttggagag gaaattcatc agtgcgcccg ggcgctcggg gaagacgaag cggtacacca
     8881 cctcgttctc ggcctgcggt gcgcgcccgc ccaccatgta gcgcacgtgc gacttggcca
     8941 tctcgtcgtc ggtgaggtcg agcgcgggca gctcgtggcg ctccagcatc tcgaccaggc
     9001 ggccggcctc gttgcggttg tgcacggtga cgccgacgaa gatgtgggcg cgctcggcgt
     9061 cggcgtagcg gtagttgaac tcggtgatgt tgcggttgcc gagcacgctg atgaacttgc
     9121 ggaaggagcc cggcttctcg gggatggtca ccgcgagcac ggcctcgcgc tgctcgccga
     9181 gctcggcgcg ctcggccacg aagcgcaggc ggtcgaagtt catgttggcg cccgaggcca
     9241 ccgccaccag gctcttgtcg cgcagcttgt tgcggcgggc gtattccttg gcgccggcga
     9301 ccgcgagcgc gccggcgggc tcgaggatgg agcgggtgtc ctcgaagaca tccttgatcg
     9361 ccgcacagat ggcgtcgttg tcgaccacga tcatctcgtc gacatactgc tggcagaggc
     9421 ggaaggtctc ggcgccgacc tccttgaccg cggcgccatc ggcgaagatg ccgacctgtt
     9481 cgagcgcgac gcgcctgccc gcggcgagcg agcgcgtcat cgcgtcggcg tcgaccgcct
     9541 cgacgccgat gatcttcgtc tcgggacgca ggcgcttgat gtaggccgcg accccggcga
     9601 tcagcccgcc gccgccgacg cagcagaaca ccgcgtggat cggcttcggg tgcgcgcgca
     9661 ggatctccat accgaccgtg ccctggccgg cgatcacgtc ggggtcgtcg aaggggtgga
     9721 cgaaggtgag cttttccgcc ttctcgagct cgagcgcgtg ggcgtaggcg tcggaatagg
     9781 actcgccggc gagcaccacc tcgccgccgc gtgccttgac cgcgtcgatc ttgatctgcg
     9841 gcgtggtgct cggcatcacg atcaccgcgc gcacgcccaa cctggctgcc gacagcgcca
     9901 cgccctgcgc gtggttgccc gccgaggcgc agatcacgcc gcgcttcagg gcctgcggcg
     9961 acaggttcgc catcttgttg taggcgccgc ggatcttgaa gctgaacacc ggctgcatgt
    10021 cctcgcgctt gaagtagatc cggttgtgca cgcgcgccga aaggttggcg gcgaggtcga
    10081 gcggggtctc gacggcgacg tcgtacacct gcgcgttgag gatgcgttcc aggtaatcgg
    10141 gtgtggagct catggccggc cagtgggctg ctgcaaagcg atcgagcgta acagccggcg
    10201 gcggcgcgcc gcaagtgcgc gcgcttcagt ccgcgcgctg ggcgccttcg gcatgcaggg
    10261 cgcgcgcctg gcggtcgatg aactcctggg tggagtcgat gccgcgcagc ttgaggatct
    10321 tcgagcgcac cgcggcctcg agcagcaccg cgaggttgcg tcccgccgcc accggtagca
    10381 ccacgcgcgc gatcttgacg ccgaggatgt cctgcgtctc ctgctgcagc ggcagtcggc
    10441 aggggtcgtc ggggcctggc tggcggcggt cgaggtggca gatcaggcgc aggcgcatct
    10501 tccgccggca cgcggtctcg ccgaagatgg tgcggatgtt gatcaggccg aggccgcgca
    10561 cctcgatgaa atcctgcagc atctcggggc agcggccttc gagcaccgtg ggtgcgatgc
    10621 gcgacagctc gaccacgtcg tcggcgacca ggccgtggcc gcgtgagatc agctcgaggc
    10681 cgagctcgga cttgccggcg cccgagtcgc cggtgatcat caccccaagg ccgagcacgt
    10741 ccatgaatac gccgtgcagc gagaccttct cggcgagctc gcgcgacagg tagaggcgga
    10801 gctggtcgat cacgctcgcc gaggggtggc gcgccgtgaa cagggcgacg tcgtgggcct
    10861 cgcagatgcc gtggaggatg ttggggacct cgcagccgtc ggcgacgatg atcgcgggcg
    10921 ggcgcgcgga gaggatctcg ttgaggtggt gggcgacctt ctcgttcgcc tggcgctgcg
    10981 cccacgcgag ctctgcggcg cccagcacct gcagccgggt ggggtggatc aggttgaggt
    11041 ggccgacgag gtccgccggc cagatgcgct cttcggcgac cgacaggcgg gcaccgatcg
    11101 gtccgctgac gtggacgagg ctcaggctct cgcgatgcgc ctcatacagc cggatcaggc
    11161 tggtttgccg catcggcgcc ccaattcacg aacaggctgt ggatctgcgc ggcatcggcc
    11221 gcgccgtgca gggtctcgcg gaactcgcgg tcgctgaaca tctgggcgag ctcggagagc
    11281 agctgcaggt gggtttcgtt ggcctgctcg ggtaccagca gcacgaacag catgtcgacc
    11341 ggacgcccgt cgggcgcgtc gaactgcacc ggggtggcca ggcgcaggaa ggcgccggcg
    11401 gcgtccttga gccccttgat gcggccgtgc gggattgcaa tgccctgacc gagcccggtc
    11461 gagccgaggc gttcgcgggt gaacaggctg tcgaacacgg tgctgcgggc gatgccctgg
    11521 ttgttctcga agagcaggcc ggcctgctcg aagacgcgct tcttgctgct cgcgtcgaga
    11581 tcgaccacca cgttggaaag cggcaggagt tgggatatca ggctcattcg caggtgggct
    11641 cgcgcactct tccgtcagcg gccgccaagg gggcgggaat ccggtccggg gcgtgtgcgg
    11701 ccgcgcttcg tgaaaacggg cgcattataa ccacaccccg gacggggagc ttcaagccgg
    11761 tcttcaggcc tccgggacct ggtgcttgag cgactcgtgg ttatgctcgg actgcttctg
    11821 cttgtacttc tgaacctgac ggtcgagctt gtcggtcatc gagtcgatcg ccgcgtagag
    11881 gtcggcatcg tcgctctcga cgaagaggtc cttgccgcgc acgtgcagcg tcacctcggc
    11941 cttctgcttg agcttctcga ccgacaggat gacggtcacg ctggtgacgt tgtcgaagtg
    12001 acggatgacg cgatcgagct tggaggtcac gtagtcgcga atggcggggg tgacttcgac
    12061 gtggcgcccg gtgatgttca gattcatgga tgactcctgt tgttgtcaga gggatttgcg
    12121 caggctgacc ggcgggatgt tgagggattc tcgatacttg gcgatcgtgc gccgtgcgac
    12181 gacgattccc tgctggccga ggatttcggc gatcctggcg tcggacagtg gtttcttgct
    12241 gtcctccgcg tccaccagct ggcgaatcag cgcgcgaatc gccgtggagg aagccgcacc
    12301 gccggtgtcg gtcgcgacat ggctgccgaa aaagtacttg agctcgaaga ctccgcgcgg
    12361 tgtcgccatg tacttctgcg tggtgacgcg cgacacggtg gattcgtgca gctcgagctg
    12421 gtctgcgatc tcccttaggg tgagtggccg catcgccacg tccccatgat cgaagaactg
    12481 tcgttgctgg tcaacgatgg cctgggagac gcgcaggatg gtgtcgaagc gctgctggac
    12541 gttcttgatc agccagcgtg cctcctgcag ctgaccgccc aggccgccgc cctgtgcgcg
    12601 gttctgctgc agcaggctgg cgtacaggcg gttgatgcgc aggcgcggca tcgcctcctg
    12661 gttgaggctc acggtccatt ggccgcgcag cttgcgcacg acgacgtcgg gcagcacata
    12721 gcgcgtctcg gtggtggagt agcgcgagcc cggatggggg tcgaggctgc agatcagcgc
    12781 ctgggcctcg cgcaaggcct cgtcgtcgca gccggtgagc ttgcggatgc gggcgaagtt
    12841 gcgctcggcg agcaactcga ggtggttggt gacgatctcg agtgcgagcg cgcggatggc
    12901 gctctccggc agcgcctgca actgcagggc gaggcactcc tgcgggctgc gcgcgccgat
    12961 cccggccggc tcgaggctct gcacctggcg caaggcgatg gcgaggtcgt cgagctcgac
    13021 ctcggcgtcc tgcggcagca gttcgaggag atcttcgagc ggctggtgaa ggtagccgtc
    13081 gtcgtcgagc gcctcgatca ggaagcgcac gagcgcgcgg tcacggtcgg aaaggggcga
    13141 cagcgcgacc tgctggccga ggtgctcgcg cagcgacacc ccggccgcct ggatgtcctg
    13201 gtagtcgcct tcgtcgtcgt cttcgctgcg gctggaggcg ccctggccca cgttggacca
    13261 gtcgatgccc tcgtcctcgc tgctgccttc gccgccctcg tgcgtgatcg attcacctgc
    13321 cggctcggct gcgggctccc gggccgcctc gcgttcgggc gcattgccgg gcggggctgc
    13381 gggggtgtaa tcgccgccac cgtcgccgtc ctcgcgctcg agcatcgggt tctcgagcag
    13441 gacgcgctcg atctcctggt tcagctcgat cgtagacagc tgcagcagct tgatcgactg
    13501 ctgcagctgc ggcgtcagcg tgaggtgctg ggagagcttg agttggaggc tgggtttcat
    13561 cgcatcgggc cggagggcgg gcttacaagc ggaagtgctc gccaaggtag acctggcgca
    13621 cccgctcgtt ctcgatgatc tcggtcggct gcccgctcgc cagcacccgg ccctcgctga
    13681 tgatgtaggc tcggtcgcag atgcccaggg tctcgcgtac gttgtgatcg gtgatcagca
    13741 cgccgatgcc gcgctccttg aggaagcgga tgatcttctg gatgtcgatc accgcgatcg
    13801 ggtcgacccc ggcgaagggt tcgtcgagca ggatcaggcg cgggtcggtg gcgagcgcgc
    13861 gcgcgatctc gcagcgtcgg cgctccccgc ccgagagcga gatcgcggtg ttgtcgcgca
    13921 ggtggtggat gcccagctcc atcagcagct cttccagccg ctcctcgacc tggcggcgat
    13981 cgagcccctg cagctcgagc acggcgcgga tgttctcggc cacgctgagc ttgcggaaca
    14041 cgctcatctc ctgcggcagg taggacagtc cgaggcgggc gcgggcatgg atcgggaggt
    14101 gggtgaggtc ggtgccgtcg agggtgatct ggccgccgtc ggcgcgcacc aggccgacga
    14161 tcatgtagaa gcaggtggtc ttgccggcac cgttggggcc gagcaggccg acgacctcgc
    14221 ccgagccgac ctcgaagccg acgtcgtgca cgacggtgcg cgccttgtag cgcttttgca
    14281 ggccggcgac cttaagcaga ctcatcgtag ggctctttca gcagcttgcg gatcagctcg
    14341 ggggcgaagc cccgggtttg caggaagcgc gcctggcgcg cccattcgcg cgcgtcggcg
    14401 ggcggactgg agaagcggcc gcgcagcacg gcacgtgccc gttccgcctc ggattctacg
    14461 cactcgccgg cgagcgcctc gtcgatccgg tcacggtcga tgccgcggcg cgcgagttcg
    14521 ctgcgcagcc gcgcggcgcc gaagcgggcc gccttgccgc gcacgaaggc ctcggcgtag
    14581 cgctcgtcgg actgcaggcc gagctcgcgc atgcgctcga tgaccgcctc gatctcggcc
    14641 gtttcgccgt ggggcgcgag cttgcgcgcc agctcggcgc gcgagtggtc gcgccgggcg
    14701 agatggcgga gcgcacgttc gcgcaggctc ggctcgccca tttcgtggtc gccgcgctca
    14761 ggcctcggcc ggcgcggggg tcgaggcggc cgccggtggc agctcgggca ggccgaccgc
    14821 gacccgcacc ttgttctcga tctcgcgggc gagcgccggg ttggcgcgca ggaactctcg
    14881 cgagttgtcc ttgccctggc cgatcttgtc gccctggtag gcataccagg cgcccgactt
    14941 gtcgacgatc ttgtgctcca cgccgaggtc gatgatctcg ccctcgcgcg agatgccctc
    15001 gccgtagagg atgtcgaagt gggcctcctt gaaggggggc gacaccttgt tcttgaccac
    15061 cttgacacgg gtctcggaac cgaccacctc gtcgcccttc ttgatcgtgc cggtgcggcg
    15121 gatgtccatg cgcaccgagg cgtagaactt gagcgcgttg ccgccggtgg tggtctcggg
    15181 gctgccgaac atcacgccga tcttcatgcg gatctggttg atgaagatca ccagcgtgtt
    15241 ggtgcgcttg atgttggcgg tgagcttgcg cagcgcctgc gacatcaggc gcgcctgcag
    15301 gccgggaagc tggtcgccca tctcgccctc gatctcggcc ttgggtgtga gcgcggcgac
    15361 cgagtcgacc accacgatgt ccacgccgcc cgagcgcacc agcatgtcgg cgatctcgag
    15421 cgcctgttcg ccggtgtcgg gctgcgagat cagcaggtcc tggatgttga cgccgagctt
    15481 ctcggcgtag ccgacgtcga gtgcgtgctc ggcgtcgatg aaggccgcgg tgccgccaag
    15541 cttctgcatc tcggcgatga cctgcagggt gagggtggtc ttgccggagg actcggggcc
    15601 gtagatctcg accacccggc cgcgcggcag gccgccgagg ccgagcgcga tgtcgagccc
    15661 gagcgagccg gtggagacgg tctggatgtc gcgttcgacg ttgccgtcgc ccatgcgcat
    15721 gatcgagccc ttgccgaact gcttttcgat ctgcgagagc gcagcggcga gggccttggc
    15781 cttgttttcg tccatggaag tgcgtcctgt ttgattgccc gattatggca caaagattgc
    15841 agacatgcgg ggatgcaggt ctgatgccgt aagtgtagag cctgtatgca attacagcaa
    15901 atatgcgaat caggtttctg cgccgggcag ggccaatggt ggcgggatgg cctgcacgca
    15961 ggtggcgtgc aaggtgcacc gcctcagcgg cagcgctcga gcacgccctg cagcgcgagg
    16021 atcaccgtct gccggcgtac cgcggcgcgg tctccgggca gctgcaccgt ggtcgtcgag
    16081 atggaggcgt cgcgtcgtgc ccagccgatg cagaccgtgc cgacgggctt cactgcgctg
    16141 ccgccgcccg gtccggcgat gcccgacacg gccaccgcga ggtcggcgcg gctgcgggcg
    16201 agcgcgcccg cggccatctc gccgacggtg gcctcgctga ccgcgccatg gctttcgagc
    16261 gtgtcgtcgc gcacgccgag catgtcggcc ttggccgcgt tcgaataggt cacgaagccg
    16321 cggtcgaacc agcccgaact gcccgcgatc gcggtgacgg cctcggcgat ccagccaccg
    16381 gtgcaggact ccgcggtggc gagccacagc ccgcgggcgg ccagggcttc gcccacccgg
    16441 cgcgccagcc catcgagttc atgatcggtc atcgcgtcag ttcccttgca ggtggaccag
    16501 caccgcgagc gccagcaggg catatccggc ggcgacgagg tcgtcgaaca tgaccccgaa
    16561 gccgcccttg aagctgcggt cggcccagcg caccggtggc ggcttgacga tgtcgaagaa
    16621 gcggaagagc gccaccgcga ccgcctgcca gagcagtccc ggcggggtga acagcagcac
    16681 cagccagatc gccaccatct cgtcccagac gatgccgccg tggtccggca cgccgagcgc
    16741 gcgcccggtg cgttcggcgg cgagcacgcc ggcgaggaag aagctggcga gcagggcgag
    16801 gaagacgaac tccgaaaccg gggtgcggat cagcgggtag agcgcccagc cgagcagcgt
    16861 gccgaccgtg cccggcgccc atggcgacag tccggccccg aagcccagcg agatgaagtg
    16921 ggcggggtgg ctcaggagca ggcgggtggt ggggcgcatg gtcgtgtcgg agggtgggcc
    16981 ggagcggatc tcaggcgaag tgatcgtagc cgtacgcggc cggtgccgcc agtgtgccgt
    17041 ccgcttcgcg cagcatcagt cgctcgcgtt cgcgggtcaa ttcgccgatg cggtgtaggg
    17101 ggaggccgag ccgggcggac aaggcttcga tcgcgccacg atggcggggc ggcgcggcga
    17161 acagcagttc gtagtcgtcg ccgcccgcga gcaggcagcg ccggcacagc gcggcgtcgg
    17221 cgccgctggc ggcaagcgca gcgagcggca gtgcggcggc ctcgacgatg gcgccggtgc
    17281 cggagcactc caggatgtgg cgcaggtcgc cgagcaggcc gtcggagacg tccagcatcg
    17341 cgctcgccag gccgcgcagc gcgagcccga gcgcgacgcg aggttgcggg cgctgcaggg
    17401 catcgacgaa ctgggcgcgg tgcggcgcgt ccagctcggc ctccccgcgc aaggccgcga
    17461 gcccgagcgc agcgcagccg ggctggccgg agacccacag atcgtcgccc gcgtgcgcgc
    17521 caccccgggt gatcgcagcg ccggccggga cctcgccggc gatggtcacc gagagcgcga
    17581 gcggtccgcg cgtggtgtcg ccgccggcga ggtcgacgcc gaaggcgtcg gcgcaggcga
    17641 agaagccgcg cgcaaaggcc gcgatccagg cctcgtccgc ccgcggcagc gcgagcgcga
    17701 ggaaggccca gcgcggctcg gcgcccatcg cggcgagatc ggagacgttg accgcaagcg
    17761 tcttccagcc cagtccttcg gggtcggtgt cggcgaagaa gtgggtgccc gccaccagca
    17821 tgtcggtgga cacggccacg cgcatgccgg gacgcggtgc cagcagcgcg gcatcgtcgc
    17881 ccacggcgag ctcggtgtgg cgcgcggggc gggtgaagtg gcgccggatc aggtcgaatt
    17941 cggagggcat ggcagcaagc gtcgggcggc ggaccgcgag cttaccgcgg atgcggccgc
    18001 acgggcatcg gtgccgaatc cgcgggcggc ggtcgtggcc cccgtcggcg ccgccccgag
    18061 cgcccgcctc gcagccaccg ccgcccctac acggcgcgcg cgatggtcat gcaggagcgc
    18121 cggcaggcgc gaatgcagtg gtgccatacg cgaccatcgt cggcgccgcc ccgaccgccc
    18181 acctcgcctg cgccgccgcc ctacacggcg cgcgcgatgg ttcatgtagg agcgccggca
    18241 ggcgcgaatg cagcggtgcc tgtggtgacg tgttgcggtg gctggagtgc cgtgttcgcg
    18301 gctgccgtcg ctcctacagg gggtactcag ccgtggcggc cgaggagctt ggccttgagg
    18361 gtgtcccagt ccaccgcgtc gagcgtgttc ttgaccagca ggccgaggtc ggtgtcgcct
    18421 tccatgcgca ggcggcggct gaagaagagc gtgtcggggt cttcctcgcg cagcgccagg
    18481 gccatgaagt cgcgcgtggt ggcggagagg atcaggtccg gcttggcgcc tgcggtcggg
    18541 gtggcacggc ggaaaccgcg ctcgcccagg gtgaagtcga gcgtcagccc tgcgtccagc
    18601 acgcgcatct gcaggtgccg gccgctgagc ggttcgaggg tgtcgcgcgg caggatgcgg
    18661 tcgagcgcga ggttgagcgc gagcgtcagc acatgggtgg gcggttgctg gggcaggcgt
    18721 gccaccagct tcgccaccgg ggcgggcacg gtgaagtcgg ggatgcgcag ggtggcgagg
    18781 cgttcgccga tgcgctggcg caggctgccg ggcagcagtt ccgagggcag cggcgggcgg
    18841 ggcagggcgg gcagggcggg catgtgcgga ctccgggtgt gcggcagttc ggaaaggggc
    18901 tcaggcggcg acgtactgct cgacgccggc acggccgtgc cagaagccgt tgcagggctc
    18961 ctcgaccatc cactcgcggc tggcagcgag cgcgtcggcg gggctgcggt ggccgtcgag
    19021 cgcggcgcgg aaaagctcga tgatctggcg cgtgtgcgca ccctgtgggc tgatgcgcag
    19081 cacctcggcg ttggcgtgca cggcgggcag gtcgccgagc aggttgtgca cccgcgccga
    19141 ctgcgtctgc acgccattga gcgtcaggaa gggggcgccc tcgcgggtgc gcagcgtgat
    19201 cccgtccatg atcgacaggc agcggaactc gcaggtgtcc ttctgcaggt tgaagtggcg
    19261 ggcggtgaag cagcgcgccg agtgcgccag cggcaggcgg ccgtaggcga agacctcggt
    19321 ctggatcggt ttggcgagcg ccgcgcgcac ctcggccagc gccgcgcccg acatctcggg
    19381 agcgaccgcc cagcgtgtcg cgcccgagtc gatcatgagc tgcagcgtca cggggttgaa
    19441 gatgttcagc gtgggaccgg cgatccagtt gtccacgccg gcctcggcga gcaggcgcac
    19501 cgcgcccatg tcgttggcct cgacacggaa gtcgtgctgg ccgacgatgc ggcgcagggt
    19561 cttgaggtcg gactcggact cgatcagggc ctgcgagctg atcaccacct ccttgccggc
    19621 ggcggcgagg accttgccga cctccagcca gtcgtccagg cgcagttcgt ggcggcgcga
    19681 gcatacggtc tcgccgaggt agacgctgtc gagcggggct tcggccatgt cggcgtagaa
    19741 gtcgagcacg ctctggtgcg gccagtagta gagcaggggg ccgagggcga gtttcatcgt
    19801 gcggttctca tgcgggtggg ggatgcgccg cgcgggcggc cggcgccgcg caggcgcccg
    19861 gtccgctggg cggcgatcgg gttcggtcgg ggcgacgacg cgcgggcgtg cggcgcgagg
    19921 ctcacttcca cgggcggtaa taggcgccca gggtgtggct ctggccttcg gagaccttgt
    19981 tgagctcggc catccacgcc ggcagcacgc tgaaggcctc ggcgccgccg cggttgagct
    20041 tgtcgagcgc ggcgcgccac accttggtga cctgggcgac gtaggccgga ctgcgctggc
    20101 ggccctcgat cttgatcgcg cggatgccga tgcgcgcgag ctcgggcagc aactcgaggg
    20161 tgttgaggct ggtcggctcc tcgagcgcgt agtaggtctc gtcgttgacc tcgaaacggc
    20221 ccttgcacag cgtcgggtag ccggcgcgtt cgccctcggc gaagcggtcg atgaggatgc
    20281 cgttgaggcg cgtctccatg ccgcgcgggg tgtcttccca gcgcacgtgc ttgccgggcg
    20341 agcaggcgcc gttgcagttg ggcgactcgc cggtggcgta ggccgacagc gcgcagcgcc
    20401 cctcgaccat cacgcacagg ccgccgaagc cgaacacctc gatctcgacc ggggtgttgg
    20461 cgaccacgct ctcgacctgg gccatcgaca gcacgcgcgg cagcaccgcg cgctggatgc
    20521 cgaagcgctc gcggtaccag ttgatcgcct cgtagctggt cgccgagccc tgcaccgaca
    20581 ggtgcaggcg cagctgcggg tgggtcttgg tcgcgtaggc catcagcccg gggtcggcga
    20641 ggatcaccgc gtcgaccccg tactcggcgg cgcgatcgat cgcctgcgtc cagctcgacc
    20701 agttgtcggt ctggggatag gtgttgagcg ccagcagcac cttgcgcttg cgcgcatgcg
    20761 cataggcgac gccctcgcgc acctgcgccg gatcgaagtt caggccggag aagttgcgcg
    20821 cgttggtggc gtccttgaaa ccgagataga cgcagtcggc gccgtgatcg atggccgtct
    20881 tgagggccgg gaggctgccc gcggggcaga cgagttcgat cggggaagac acggacatgg
    20941 agcgggattt ccagggggaa aaaacgccgc aaccataaac gaggacggcg gccggcgcgt
    21001 tgatcaccat caaacgcgcc ggccgcggct gcgagccggg tgcgcccggg ccggtcagcg
    21061 gtgggtgtgg taggtgcccg ccgcggcgtg gtggccgccg atgtgcgggc ggtgatgcgg
    21121 ctgccggccg atcaggccgc ctgccagcat gccgagtgcg ctcgccgcca ggccgtagag
    21181 ctggggctcg atgtcgcctt cgggcacgaa gagctcgaac aggatccagg tcgacaggcc
    21241 gaggatgatc gacagcgccg cgccgaggtt gttggcgcgc ttccagaaca ggccggccgc
    21301 gagcggcacg aaggcgccgg ccagcgtgat gcggtaggcg ttctcgacca tctggtggat
    21361 cgaggactcg gtgctggtgg cgtaccaggt gaccagggcg gtgaacacca ccacggtcat
    21421 gcgtgtgctg agcaggaagg cgcggtcgct catgccgggg aggaagccgc gcagcacgtt
    21481 ctcggagaag gtcaccgagg gcgcgagcag ggtgcccgaa gcggtcgaca tgatcaccga
    21541 cagcagcgcg ccgaagaaga tcacctgggc gtagaagggc atgtactgca ggatcagcgt
    21601 cggcaggatg agctgcgagt cctgctccat caggcgctcg accatgcccg gatcgatgat
    21661 gttggcggtg taggcgagga agagcggcac cgcggcgaag aagaagtagc tcacgccgcc
    21721 gagcgtggtg ccccagatcg cgacggtctc gttcttcgag gagttgacgc gctggaacac
    21781 gtcctgctgc gggatcgagc cgagcgccat ggtggcgaag gcggcgatcc aggcgatgat
    21841 ctcgaccgca tcgagggagg gcaggaactc gaacttgccc tcggccgcgg ccttggcgac
    21901 cacgtggtcg aagccgcccg ccatgtcgcc ggcgatcgtg ctcacccaga tcaggccgat
    21961 cacgatcacg atcatctgca cgaacgtggt catggctacc gaccacatgc cgccgaaaag
    22021 ggtgtagacg aggaccacgc cggcgccgat cagcatgccc tggttcatcg tcacggcgtc
    22081 gcccgagagc acgttgaaca ccagcccgag cgccgtgatc tgcgccgcca cccagcccag
    22141 gtaggagagc acgatgcaga tcgacagcac gagctcggtc gtgcggttgt agcgcatgcg
    22201 gaagaagtcg cccagcgtga gcaggttcat gcggtacagc ggccgggcga agaggaggcc
    22261 gaacagcacc aggcaggccg aggcgccgag cgggtcggag atcagcccgc tgaagccttc
    22321 ctcgatgaag gtggcggaga tgccgagcac ggtctctgct ccgaaccagg tggcgaacac
    22381 catcgccagc acgacgatca tcggcaggtt gcggcctgcg gtgatgtagt cacgcgcgtt
    22441 gtgcacccgg gtggcggcat acaggccgat gccgatggag acgaccagat aggcgacgac
    22501 aagccagagc agcatggttg ggcccttcgt gttggcgcat ccgcgcgcgt gagcgaaaaa
    22561 agagggcgcg agtttaccaa cagaacgccc ccgcgggggg cgggatttgg gcgccaaggg
    22621 cttgatcgtt cgcgctttat cgcacatgcg caacgccgcc gcgctgcgcc gtgcctcagc
    22681 cgaacaggcg gtagagctcg aggccgagca ggccgatggc gacggcgccg atgatgagca
    22741 gcaggcgccc ctgggtgcgc tggccggcgg cgagctcgtc gaggcgttgc tgctgcgcgc
    22801 tctggtggcg ggtcgactcg gtgagcgcgt gatgcaccag gcgcggcaac tgcggcagcg
    22861 tcccggccca cgcgggcgcc tcttcccgga tgccgcgcac cagcgcgcgc acgcccatgc
    22921 gctcgtccat ccagcgctcg aggaagggct tggcggtctt ccacaggtcg agctcggggt
    22981 cgagctggcg gcccaggcct tcgatgttga gcagggtctt ctgcagcagc acgagctgcg
    23041 gctgcacctc catctcgaag cggcgtgcgg tctggaacag gcgcagcagg gtcttgccga
    23101 aggagatgtc cttcaagggc ttgtcgaaga tcggctcgca tacggtgcgg atcgccgcct
    23161 cgaactcgtc cacccgcgtc ttcgccggca cccagccggc ctcgatgtgg gccagcgcca
    23221 cgcgccggta gtcgcgctgg aagaaggcga ggaagttggt cgcgaggtag ttcttgtcca
    23281 cctcgttgag ggtgcccatg atgccgaagt cgagcgcgat gtagcgcccg tcggagtgca
    23341 cgaagatgtt gcccgggtgc atgtcggcgt ggaagaagcc gtcgcggaag acctgggtga
    23401 agaagatctc cacgcccgcg cgcgacagcg ccttcaggtc ggtgccctgg gcgagcagcg
    23461 ccggcgtctg cgagatcggc acgccgcgca tgcgctccat caccatgacc ttgctgccgc
    23521 accagtccca gtagacctcc ggcacgatca gcagcgacga gtccttgaag ttgcgccgca
    23581 gctgcgagca gttggcggcc tcgcgcatga ggtcgagctc gtcgtgcagg tacttgctga
    23641 actcggcgac gacctcgcgt ggcttcaggc ggcggccttc gggccagatc ttctcgagca
    23701 gcaccgcggc gacctcgagc agcgccaggt cgtgctcgat cacacgctcg atgccggggc
    23761 gcagcacctt gaccgcgacg tcggtgccgt cgggcaggcg ggcgaaatgc acctgcgcca
    23821 ccgaggccga ggccaccggc gtgcgctcga aatcatcgaa aacggtgtcg atcggcttgc
    23881 cgtagaagcc ctccagcacg gccagtgcct gctcggtggg gaagggcggt acgcggtcct
    23941 gcagcagcgc gagctcctcg gcgaggtcgg gcggaagcag gtcgcgccgg gtcgacagca
    24001 tctgcccgaa cttgacgaag atcggcccga gcgactcgag cgcctggcgc aggcgggcgc
    24061 cgcgcgactc ggtgaagctc cgccagaaga agaccttgtg ccacacgtgc gcgaggcggc
    24121 cgctgctgtc ggcgtcgagc accatgcggt cgaggccgaa gcgcaggctg acggagacga
    24181 tcttggcgag gcggaagagg cgcacgatgg aaggccgggc agacgcaaac ccggaactgt
    24241 agcccgaaag cggcagcggt ggaacgggcg tggacttgcc cgcgcgccac cgggatgcaa
    24301 actgcgctca catcctcgcc ggggcggacc ctgccgatcc gctataatcg cgcgtttcga
    24361 attcattccg agtgccatga gcgccgatcc caaagtcctg ctgaccgacc tgctccagac
    24421 cgcgctgaag agcgtcgccc cggatctcgc cgccaccccc atcctgctgg agcgccccaa
    24481 gcaggcgagc cacggcgact tcgccaccaa cctcgcgctg caactcgcca agccactcaa
    24541 gcgcaacccg cgcgagctcg ccggtctgct gctggccgag ctgccgccgt cgaagctggt
    24601 cgccagggcc aaggtggccg gcgccggctt catcaacttc acgctcgcct cggacgccaa
    24661 gaccgcggtg gtgcgcgagg tgctggccaa gggcgcggac ttcggccgcg gcgctgccaa
    24721 gggcgtcaag gtgcaggtgg agttcgtctc cgccaacccg accgggccgc tccacgtcgg
    24781 ccacggccgc ggtgcggcct acggggcctc gctctcggac gtgctcgcct tcgccggcta
    24841 cgaggtcagc cgcgaatact acgtgaacga cgccggtcgc cagatggaca tcctggcgct
    24901 gtcgacctgg ctgcgctacc tcgccttctt cggcgtcgag gtgccctttc cgcccaacgc
    24961 ctaccagggc gattacgtga tcgacatggg ccgcgacatg cgcgacgccc accaggaccg
    25021 cttcgccagg gtcaccctcg agcaggtgct cgccggcacg cccggcctgc cgccttccga
    25081 tcgcaaggac gacgagtcca agcagcagcg cgaggagcac ctcgacgcgc tgatcgccaa
    25141 cgccaagaag ctgctcggcg aggactaccc ctgggtgcat ggcttcgcgc tcaacgagca
    25201 actcggcgat ggccgcgagg acctgcagga gttcggcgtg cgcttcgaca agtggttctc
    25261 ggagcagagc ctgttcgaca ccggcctggt cgagcgcgcg gtgacccagc tcgagaaggc
    25321 cggccacatc tacctgcagg acggcgccag gtggttccgc tccaccgcct tcggcgacga
    25381 gaaggaccgc gtcgtgcagc gtgagaacgg cctctacacc tacttcgcct ccgacatcgc
    25441 ctaccacctc aacaagtacg agcgcggctt cgaccgcatg atcgacatct ggggggccga
    25501 ccaccacggc tacatcccgc gcgtgaaggg cgcgatcgcg gcgctcggac tgccgccgga
    25561 gaagctcgag gtcgcgctgg tgcagttcgc ggtgctctac cgcgacggcc agaagacctc
    25621 gatgtccacc cgctcgggcg agttcgtcac cctgcgcgag ctgcgccgcg aggtcggcaa
    25681 cgacgcctgc cgcttcttct acgtgctgcg caagtccgac cagcacctcg acttcgacct
    25741 cgacctcgcc aagagccaga gcaacgagaa cccggtgtac tacgtgcagt acgcccacgc
    25801 ccgcgtgtgc tcggtgctca accagtgggg cggcgaggcc gccgagctgg ccgcggccga
    25861 cctcggcctg ctgcacaacg agcgtgagct cgcgctgtgc gcccgcctgg cgagcttcgc
    25921 cgagctggtg cagaacgccg ccgccgacta cgcgccgcac caggtggcct tctacctcaa
    25981 ggacctcgcc gccgacttcc acagctggta caacgccgag cgcatgctgg tcgaggacga
    26041 ggccgtcaag ctcgcgcgcc tcgcgctcgc cgccgcggtg cgccaggtgc tggtcaccgg
    26101 cctgaagatg ctgggcgtgt ccgcgcccga gtcgatgtga tgcagggggt gcaatcgtga
    26161 gtcgagatcg caggccggcc cgcaagccgg cgcgcgcacc ggcgaagagc gcaggcggga
    26221 cgctgatcgg gatcttcatc ggcctcgtct tcggcgcgct gatcgcggcc ggggcggcgt
    26281 ggtacttcac ccgcagcaat cccttccagg ccgcgccggt ggcgccgcgc gtgcaggcac
    26341 cggccgagca gggaccggcg gcactgcccg ggaaaccggg cgaccgcccg gtggccaagc
    26401 aggatttcga gttctaccgc atcctgccgc agggcgacaa cgtgccgtcg tcggcggccc
    26461 aggtcgtccc ggtgcctgcg ccccaggtgc aggcgccgcc tgtggccgtg cccgcgcagc
    26521 aggccccggc gccggtgttc gaggcctcgc cgcagcccgc ggcgctggcg ccgagcccgc
    26581 cgccgcgcaa cgagcgcatc tacctgcagg tgggctcgtt cgagaacccc tccgaggcag
    26641 acaacctcaa ggcgcggctg gcgctctcgg ggatccaggc gagcgcccag cgcacccagc
    26701 tgcccgacgg acgcgtcgtg caccgcgtgc gcgtcggccc cttcgccaag cccgaggaca
    26761 tgaacccgat gcgtgcccgc ctctccgacg ccggcttcaa cgcctcggtg agccgcaacc
    26821 agtgagcgtg gacgtaccac cgcgcatgga acgtccctgc gccgtccgcg tctcacccag
    26881 ccctagtcaa tggagttccg catgaatcgt cgtgatgccc tcaagctggc cggcctggcc
    26941 ctcgcccttc ccgccgcctc ggtcgtgcag gcgaacgagc ccttccagat catcgagccg
    27001 gcgcagaagg gagacgatcc cgcgaagatc gaggtgctcg agttcttcca ctatggctgc
    27061 ccgcactgcc gcgacttcca cccgctgatc accgcctgga agaagaagct gccggccgac
    27121 gtcgccttcc gcgcggtgcc tgcggtgtgg aacaacgccc agctgagcgg cctggcccgc
    27181 ctgttctacg ccgcgcagat caccggcgag ctcgccgcgc tcgagccggc gatcttcgcc
    27241 gcggtacagg acgacaagcg cccgctgttc aacgagcagc aggtgtccga gtggatcgcc
    27301 ggcaaggtgg gcgatgcggc caagttcatc gagacctaca agtccttcgg cgtcggctcg
    27361 atggtgcagc gcgccgacca gctcgcacgc gcgttgaaga tccagggcgt gccggcgatg
    27421 gtggtcggcg gccgctacct cacctcggcc tcgctcaccg gcagccacga gaacaccctc
    27481 aaggtcgccg acgagctgat cgcccgcgtg cgcaaggagc gcggctgaac atgagcgatc
    27541 gcgacgccgg cgcgctgccg cacgcggccg aggccgccga gcgcaggcgc atccagcgct
    27601 tcctggccct gcgccgtggc gagccctatc tgtgggtgac gatcggtggc gagcgcatca
    27661 cgctgcgtga catctcggtc gatggcttcg cgatcgccgc agcgacgccg cctgcgggcg
    27721 ccgcgccctt cgacttcgtg ctgcagcgcg agggcgtgcc cgaccagatc cgcggtcggg
    27781 cgcaggtggt caatttcatc gctgcgagcg ggcaggcggg ctgccgcttc ctcgcgctcg
    27841 agggcgatgg cgccgagcgt ctgcgcgact ggctggtcgc gctggtgatc atgaacgcca
    27901 gcgtgcgcat cagcgagaag gatgcggccg cgatcgttgc cggaccgtcg ctgatctgaa
    27961 accggctgtg cgcgggcgca gcctcccttc tcccgggcgc gcaaagacaa ggccgccgcg
    28021 accctcgcgg gcgcggcggc cttcgtctgc gtggtcgccc ggtcaggcgc ggctgcggcc
    28081 cgccgtgcgc tccgcctcgc ggcggcgctg gcgcggcttc tgcatcgccc acaccagggc
    28141 gatgagcgcg aacgcgggga tgtacatcca ctccttgtcc ggccgctcgc ccgagggcag
    28201 ctcgatgcgg acgatattgt agccctgctc gaggccgagt ttctccgcct ggctgccgaa
    28261 gcgcaccgcc gccacctgca cctggtcgcc gagcgccatc gtggtcaggc cgatcgcgcc
    28321 gaggcgctcg cgtgcgttgc cggccttttc gccgagcggc agcagcacgc ccttggagat
    28381 gtcctggccc tccaggctca tgccctcgac ccacacgcgc aggttgccgt tgcgcggcgc
    28441 ctcctcgacc aggcgcccga actcggtggc aggcacctcc tcgaagggcg ggtacagcat
    28501 gtccatccag tagcccgggc ggaacagcgt gaaggtcacc agcagcagga tcaggttctc
    28561 gtggatgcgg ctcttcgcga tgaagaaacc ctgcgtcgcc gcagcgaaca tcatgctcgc
    28621 caccgtcgcg ctgacgatgg tcagcaccag gtggaaggtg tcgctgatgc cgatcagcag
    28681 gatctgcgtg ttgaagatga acatgaaggg caggatcgcc gtccgcgcgc tgtagccgaa
    28741 ggcggtgagg cccgtgcgca tcggctcgct cttggcgatg cctgccgcag catacgaggc
    28801 caggcccacc ggcggcgtca cgtcggccat gaggccgaag tagaacacga acaggtgcac
    28861 cgcgatcagc ggcaccagca gcccggtctg tgcgcctagt tcgacgatca ccggcgccat
    28921 cagcgtcgat accacgatgt agttcgccgt ggtcggcagg cccatgccga ggatcaggca
    28981 gatcacggcg accaggatca gcatgatcat gaggttgccg cccgagagca gctcgaccag
    29041 ctcggtcatc gccaggccga tgccggtgag cgtcacggtg ccgacgatca cgcctgcggt
    29101 cgcggtggcg atcgcgatgc cgatcatgtt gcgggcaccg gtgatcaggc cggtgaagag
    29161 gtcggagaag ccttgccggg ccgcctcgcc gatgttgccg gtgcggcgga agagggcgaa
    29221 cagcggacgc tgggtgacga ggatgaacat caggaacagg gtcgcccaga acgccgacag
    29281 cgcaggcgag agctgctcga ccatcaggtt ccagatcagc gccgccaccg ggaggaggaa
    29341 gtgcaggccg gccttgaggg tggggccgat ctcgggcagg tattccatct tctcgtcggg
    29401 cttctccatg tgcagctcgg gatactgcgc ggcgaagcgg accaggccga cgtaggcgag
    29461 cagcatcagc acgccgacga cgaggaaggc ggcgccgccg aaggcggtct tcatccagcc
    29521 gaagccccag tagatgatcg ccgacaggat caccagcccg gagacggtca tcagcgtggt
    29581 gatcagcgtg cgctgccagg gcagcggctc gcgccgcggc aggccctgca ggtccatctt
    29641 gagggcctcg aggtgcacga tgtagtagag cgcgatgtag gagatcagcg ccggcagaat
    29701 ggcgtgcttc atcacctgga cgtagctgat gcccacgtac tcgaccatca ggaaggccgc
    29761 ggcgcccatc accggcggca tgagctggcc gttgaccgag gacgcgacct cgaccgaggc
    29821 ggccttgtcg gcgcggtagc ccacgctctt catcagcggg atggtgaagg tgccggtggt
    29881 gaccacgttg gcgatcgagg agccggagat caggccggtg ctggccgagg ccaccaccgc
    29941 cgccttggcc gggccgccgc gcatgtggcc gagcagcgcg atggccgact tgatgaagta
    30001 cgcgcccgca ccggcggtct cgagcagcgc accgaagagc acgaacagga agatgaagct
    30061 ggtcgacacc ccgaccgcga cgccgaacac gccctcggtg gtcagccaca tgtggctcat
    30121 gcccttggcg agcgaggcgc cgcggtgggc gatgacctcg ggcatgtagg ggccgaagaa
    30181 gatgtacacg aggaacaccg cggcgaggat caccatcggc aggccgagcg cgcgccgcgc
    30241 ggcctcgagc agcagcagca tgccggccac ggcggccgcc aggtccaggt cggtgggcat
    30301 gccggggcgt tgcgcaagct cgcggtagaa gatgaacagg taggccgcac agaaggcgcc
    30361 caccgcggcg aacacccagt cgacgacggg tacgtggtcg cgcggcgagc ccttgaacgc
    30421 cgggtaggcg gcgaaggcga ggaagaccgc gaaggcgagg tggatggcac gtgactcggt
    30481 gtcgttgaac acgaacacgc cgagcgagaa gggcagcggc gaggcgatcc agagctggaa
    30541 cagcgaccac gccagcgcca ccgccagcag cagctgtgcg gtcaggccgg tgggcttgcg
    30601 tccgccggtg tcggcctcgg cgacgatctt cttgagctct tcatcggaca gctcgaagct
    30661 ggccttgtcc ttgttttcgt ccgggcgggt catgaggagc gcctctcagg ttcgtgacgg
    30721 agacaaaaaa cggcgggacc tcgggggtcg ccgccgtttg cacagcagga accggcgcac
    30781 cctgcaggcg cgccggccgg cggaatcaca tccagccctt ttccttgtag tacttcaccg
    30841 cgccctcgtg cagcggggcg gacaggccgt ccttgatcat gtgctgcggc tggaggttgg
    30901 cgaaggccgg gtgcagcttc ttgaagtcct cgaagttctc gaacaccgcc ttcaccagcg
    30961 tatacacggt ctcggcgggc accttggacg aggtcacgat gctcgccacc acgccgaagg
    31021 tatcggtcgg gttcgggttg ttggcgtaca ggccgcccgg gatctgcacc ttggcgaagt
    31081 aggggtagtc ggcgaccagc ttgtcgaccg cgggaccggt gatcggcacc agcttggcgc
    31141 cgcaggtggt ggtcggatcc tggatgttgg cggccgggtg gccgacgacg taggcgaagc
    31201 cgtcgatctt gttgtcgcac agcgcggcgc tgtgctcgtc gggcttgagc tcggagacca
    31261 gcgagaagtc ggcgtcggac attcccatcg ccggcagcag gatccccatg gtcgcgcgct
    31321 ggccggagcc cgggttgccg acgttgaagc gcttgccctt gaagtcctcc atcttggcga
    31381 tgttggcttc cttgcgcgac agcacggtca gcggctcggg gtggagaccg aacacggagc
    31441 gcagctcggt gaacgcacct gcgtccttga actgggcttc gcccttcatg gcgttgaact
    31501 ggatgtcgga ctgcgacacg ccgaagtcga gctcgccggc cttgatggtg ttgacgttgt
    31561 acaccgagcc gccggtgctc tcgaccgagc agcgcaggcc gtgctgggcg cggtccttgt
    31621 tgatcaggcg gcagatcgcg ccgccggccg cgtaatagac gcccgtcacg ccgccggtgc
    31681 cgatcgtgac gaacttctgc tgggcgtgcg cgggggcggc gccgagtgct ccggcgattg
    31741 cgaaggcggc agcaagggca gtcagttttt tcatgagggc tttctccgtg aagatggaaa
    31801 tccggctgcc cgaaggcgcg ccgacagggc ggaatcggtg ctgcgggttg gggcgaggag
    31861 ccgaggatgg cggtgaaacc agcctttggc gcccgtcctg gatgttcaag cttggcacaa
    31921 aagcacccct gcctgcactc gggatttccc gaagtgcgcg gcaggcgctg atttcccgcg
    31981 ccagttgcga cgccttgcgt gccgcggcgc gctaagattc gccccccgac gccttgccga
    32041 agaccccgct catgcacgcc aggacctcac aggatgcact ccggacattg accgacgccg
    32101 ccgggcagcg gcatgtgccg gccggccccg atgcgcgcat cgtgtcgctg gtgccctcgc
    32161 tcaccgagct ggtcttcgac ctcggcctgg gcgaccgcct ggtgggccgt accggcttct
    32221 gcgtgcatcc gcgcgaggcg ctgcgtggcg tgcccaaggt cggcggcacc aaggacgtca
    32281 agctcgaacg gatccgcgaa ctcgcgccca cccacgttct ggttaacatg gacgagaacc
    32341 gccgcgagac ggtcgacgcg cttgcggcct tcgtgcccga tatcgtcgtc acccatccca
    32401 acacgccaca ggacaacctg cccctcttcg cgctgctcgg cggcgtcttc ggcgccgagg
    32461 ccgccgccgc ccggctcgcc gacgagctgc gcgccgcact cgccgaggcg gcggcgctgc
    32521 gcgcgacgct ggccgacgag cgcgtgctct acctcatctg gcgcgagccc tggatgaccg
    32581 tcgcccgcga cacctacatc gccgccacgc tcgccgaggt cggctggtac accgtgcccg
    32641 cggtggaggg cggcgagacc ggggcggcgc gctatcccgc cttcgactgg gaggcgccct
    32701 ggctggccga tgtggcgcgc gtgctgctgt cgaccgagcc ctaccgcttc cgtgcggaac
    32761 atctgccgga ggtcgagtcg ctcgcacgcc gtcccgcgct gctggtcgat ggcgagatgg
    32821 tgtcgtggta cggcagccgc gccgcgcgcg ggctgcgctg gctgatggcg ctgcggcgcg
    32881 ggatggcgtg agtcggcggt tcaggtcggt ttttcgtccg gctgcgcgag cgtctgctgc
    32941 atgcgttccg gggtgaggat ggcgaagcgc tcgcgcacga ggcgatggcg cgccaggcgc
    33001 agcagggcct tgtcgcgggt gatcagcgtc gccatgccgg ccgcaccggc gatttcgagg
    33061 aacttctggt cgtcggggtc gcgacagccg gggagcgtcc cggcgtcggc atcgtttgcc
    33121 agcacggcga tgcgggcgag gtagcgcgtg cgcaggccgt cctggcggtc cggatccagg
    33181 ccgaactggg cgtaggcaag cacgcggcgc aattcttcca gcgcgtctgc acgcgagacc
    33241 aggcggcacg atcctgcgtc gatccacgca cgtagtgtct ccagcgcggg gtcgcggaac
    33301 atccaaagcg cgagcaccgt gttggtgtcg agcacgaggg tgggcagcag ggctgcttgc
    33361 gaggagggct cggtcacgtt cgcagtgggt gagcggcgcc gccggccagg cgatgcagca
    33421 cggtgaacga aagacgggga gggttccccc tccccgtcct cattgcgacg aagctcaggc
    33481 agcggccttg gcgtcgatgc ggatcttcac gaagctgccc ggggcgtctt ccagcacctc
    33541 gagcttgccc ttgacgggat cgcgcgcctc ggtctgctca ccgtcgtgtg cggtgaccca
    33601 ggcctgccag tcggtccacc acgagcccgg gtgctgctgc gcgccttcca gccaggcgtc
    33661 ggcggtgtcg gcgagcttgg cggccgggtt cagccagtag ccgtacttgt tggccgcggg
    33721 cgggttcacg ataccggcga tgtggccgga gccgccgagc acgaagcggg tcgggccgcc
    33781 gaagcggcgg gcgcccatgt aggtgctctt ccacggtgcg atgtggtctt cgatcgtgga
    33841 gatgaagtag cacggcacct tgatcttgga gagatcgatc ggggtgccgt cgatctcgac
    33901 gccgccggcc tcgatcaggc ggttctccat gtacatggcg cgcaggtaga agctgtgcat
    33961 ggccgccggc atgcgggtcg agtccgagtt ccagtacagc aggtcgaacg ggaacgggtc
    34021 cttgccgagc aggtagttgt tcaccacgaa ggaccagatg aggtcgttgg cgcgcagcat
    34081 gttgaaggtg ccggccatct ccgagccttc caggtagccg cgctcgaaca tcttcttctc
    34141 gaggctggag acctggcctt cgtcgatgaa cacgccgagt tcgcccgggt cggtgaagtc
    34201 ggtcatggtg gtgaagaagg tcgccgaggc gatgcgcttc tggcgcttgg cggcgaggta
    34261 ggcgagcgtg gtcgcgagca gggtgccgcc caggcagtag cccgcggcgt tgacttcctt
    34321 ctcgccggtc tggcgctcga tggcgtcgag ggcggcgacg acgccttcct tgacgtaggc
    34381 gtcgaagctc ttctgcgcca ggcgctcgtc cgggttcacc caggagatca cgaacaccgt
    34441 gtggccctga tccaccgccc acttgatgta ggagttcttc tcgcgcaggt cgaggatgta
    34501 gaacttgttg atccagggcg gcacgatcag cagcggcttc ttgaggacct tgtcggtgct
    34561 cggggtgtac tgcagcagct gcatcatgtc ggtctggaac acgaccttgc ccggcgtggt
    34621 ggcgacgttc ttgcccagct cgaaggccga ggtgtcggtc atcttgacgc gcaggttgcc
    34681 gccgccgtcc tcgacgtcgc gcagcaggtt gttgaggccc ttgagcaggt tctggccatg
    34741 gctcttgacc gtctcgcgga agacctcggg gttggtcatc gcgaagttcg acggcgacag
    34801 cgcgtcgatg tactggcgag tgtagaaggt gaccttcttc tgggtctgct cgtcgaggcc
    34861 gtcgacgccg ctgacggtgt cgtggatgtg gcgcgcggcg atcaggtagg actgcttgat
    34921 gaagtcgaac aggaaatgct gctcccactc ctcgtccttg aagcgcttgt cgctcttctc
    34981 gggggcggcg accggcgcgg cgctcaggcc ggcgacgcgc atcatcgagt gctgccacag
    35041 cgagaagtag tcccacacca ggttcatctg ggcctgggca agtttgtacg ggttggccag
    35101 cagcttggcc atcatgtcca tgaaggcctg ggcgatgccg agctcgtcgg cgggggcgct
    35161 gacgcccttc ttgagctggc ggtgcacgtg gtcgctgatc aggtgcgagg cacggcgggc
    35221 gacttcggcg taggtcttgg cgacttcctg cgggtcgggc aggtcgcagg cgggggtctc
    35281 gttgctgggt gcggccatct tgttcgggct cctgttttgc ggcggggcgg tctgttgcgg
    35341 acgatgttac gaacaatggg tgaaacggat caggccatcc gcatcgacgc gtctcgagag
    35401 ggttcccgtc ttctcgagat ggttgaggtg ggcgatcgcc tctcccatgg cgaacatgac
    35461 ctgatgggtg tcgagctcac gcggaaatag cgtcggcagc aatgctgcgg cgctttgcgg
    35521 catggcacaa gccgccagaa gcacctcgca acgttcgcga tgatgctcga cgagctgctc
    35581 cacgcgtgcc cggataccct tgaaaggttt gccatgtgat ggtagcacga gcgtgtcgtc
    35641 gggcaaggtg cagaattccc gcaacgagtg aagaaaccag cccagggcgt ctccatgtgg
    35701 cgttgcagca tagacgctga cgttggtgga gatgcgcgga agcaacatgt cgcccgcgat
    35761 cagcacgccg agctcggcac agtacaggct ggcgtgctcg ggcgcgtggc cgaagccgac
    35821 gatgacgcgc cagctgtggg caccgatgcg cagctcgtcg ccggcgaaca tgcgctcgta
    35881 gcggcccggt acctgcggcg cgccgacgcg ataggcgttg ccgcgtgtga gcagcgcgtc
    35941 gcggcgcatg tcgtcgaggc cgtggcggcg gaactgctcg accatgtcgg tggcgcagta
    36001 gcccggcagc tggtgccaca ccgcctgggc ggcgaagaac tcgccctggg tcatgtggat
    36061 cgcggcatcg tcgcgcgccg cgagccaggt ggccaggccg atgtggtcgg ggtggtggtg
    36121 ggtcaccacg acgcggcgta gcggccggcc gtccgcggcg agtacggcgt tccaggcctc
    36181 acgcgtctcc tcgcgggcga agccgcagtc caccgcggcg agcgcctcgc cgtcgtcgag
    36241 cagccacagg ttgatgtggt cgagcgcgaa gggcaggcgc atgcgcaccc agcgcaggcc
    36301 gggggcgatc tcgatcgtgt gcccgggcgc gggcaggctg tcgaaggggt attcgagggg
    36361 cgtcgggctg gcggtgctca tggggtctcc tgtgtggcgg cggactcgtc cggtgcgcgg
    36421 gttcgccccc gcgcgcgcgg cgttcctgcg gtcgcgcgat tccggaatgc gatcgattac
    36481 gttaacgtta acgtattgac aggcataatt acagactcga cggagacatg aagatgcgcc
    36541 ccgaagcacc ccagttccag ccccgcgacc ccggctacgc cgagcgcgtg cgcgcgagct
    36601 tcgcgctgca gcaggcgatg agcctgatcg gcgccgagct tcccgtggtc gagcccggct
    36661 acaccgagat ccacctgccc ttcaaggcgg agatctcgca gcagcacggc ttcatccatg
    36721 ggggcgtggt cggcatgatc gccgactcgg ccgcgggcta cgccgccaac acgctgaccc
    36781 cggcggacac cagcgtgctc accgtcgagt acaagctcaa cctcgtcgcc cctgccgacg
    36841 gcgagcgcct ggtggcgcgc ggcgaagtgg tcaagcccgg acgcacgctg atcatcacca
    36901 aggccgaggt cttcgccatc cgcgagggca aatggacctt gtgcgcgctg atgcagcaga
    36961 cgatcatggc catgcacggc aagaaggagc gcgccgcctg aacggccgcc cgcaacgttc
    37021 ccccgagaga tccgtccccg aaccttcccg gagtcccgca atgccttccc gcctgtgcgc
    37081 cctcggcgcc gacgacacca ccgagctcga acatgtgcgc ggattcttcc gccaatatgc
    37141 cgcctggctc ggcgtggacc tgagtttcca gggcttcgcc gacgagatcg ccaacctgcc
    37201 gggcgcctat ggcgcggccg acggccgcct gttctacgcc gaggtcgacg gccagccggc
    37261 cggctgcgtc ggcatccgcc gcttctccga gggcgtgtgc gagatgaagc ggctctatgt
    37321 cgatcccgcc ttccgcggcc gcggcgtggg gcgcaagctc gcgctcgccg cgatcaaggc
    37381 ggcgcacttg ttcggctatc gccgcatcct gctcgacacc gtcccgtcga tgcggatcgc
    37441 ggtcaagctt tatcgcgagc tcggcttcaa ggaagtcccc gcgtattacc cctcgccgat
    37501 cgagggcacg atcttcctga ccctggacct ggagaactgg tcggaggacg aggtcaacaa
    37561 cgagaacctc ttccacctct tcgactacaa ccaggcgtgg tcgcgccaga tgcagcagat
    37621 cgaccccggc ttcttcggca agctggcgca gctgcaggcc ccggaatacc tgtggatcgg
    37681 ctgctccgac tcgcgcgtgc cggccaacca gatcgtcggc ctgctgccgg gcgaggtctt
    37741 cgtccatcgc aacatcgcca acgtggtcgt gcacaccgac ctcaacgcgc tggcggtgat
    37801 ccagtacgcg gtcgatgtgc tgcaggtgaa gcacgtcatg gtggtcggcc actatggctg
    37861 cggcggcgtc aaggcggcgc tcgagcgcac gcgcgtgggc ctcaccgacc tctggctgcg
    37921 ccacgtgcag gacgtccatg cgcgccacct gcaggcggtc gacagcctgg cgcccgaacg
    37981 ccgctacgac cgcctgtgcg agctcaacgt catcgagcag gtcgccaacg tggcgcagac
    38041 cgtggtcgtg caggacgcct ggcgacgcgg ccagcgcctc accgtgcatg gctggatcta
    38101 cggcctgcag gacggcctga tccgtgatct gggcatgaac gtcagccgcc cagacgatct
    38161 catgccgcgc tatgtcgcgg ccctggaggc gctcggtagc tgagcgcccc gcacaacgaa
    38221 tcgatcaaca cctacaacaa accaaacagg agagtcgcat gtccgatccc gtcgtcatcg
    38281 tttccgtcgc ccgcaccccg ctgggcggct tccagggtga cctgtccagc ctcaccacgc
    38341 cgcagctcgg ctcgaccgcg atcaaggccg cggtcgagcg cgccggcctc gcgcccgagc
    38401 aggtgcagga agtgatcatg ggctgcgtcc tgcccgccgg cctcggccag gcgcccgccc
    38461 gccaggccgc gctcggcgcc ggcctgccgc tgtcggccgg ctgcaccacg atcaacaagg
    38521 tgtgcggctc gggcatgaag gccaccatgc tggcccacga cctcatcctc gccggcagca
    38581 acgaggtcat ggtcgccggc ggcatggagt cgatgtccaa cgccccctac ctgctgccga
    38641 aggcgcgcgc ggggtatcgc ctcggccacg gccagatgtt cgatcacatg ttcctcgacg
    38701 gcctggaaga cagctactcc aaggaccaca agggccgcct gatgggcacc ttcgccgagg
    38761 actgcgcgag ccacttcggc ttcagccgcg aggcgcagga cgagttcgcg atcgcctcga
    38821 ccacgcgcgc gcaggccgcg atcaacaacg gcgacttcat ctgggaggtg gtgccggtca
    38881 cggtgtccgg ccgcaagggc gacgtggtgg tggacaagga cgagcagccg ttgaaggcgc
    38941 agatcgagaa gattcccacg ctcaagcccg cgttcaggaa ggacggcacg gtcaccccgg
    39001 cgaactcgag ctccatctcc gacggcgccg ccgcgctcgt gctgatgcgc aagtccaccg
    39061 ccgacaggct cggcctcaag ccggtcgcca ccatcctcgg ccacgccacg cacgcgcagg
    39121 agccgcactg gttcaccacc gccccggtgg gcgcgatgca gaaggtgctg gccaaggctg
    39181 gctggaccac cggcgacgtc gatctctggg agatcaacga ggccttcgcg gtcgtcacca
    39241 tggcggcgat gcacgagatg aagctgccgc acgacaaggt caacgtgaac ggcggcgcct
    39301 gcgcgctcgg ccacccgatc ggcgcctcgg gtgcgcgcat cctggtctcg ctgatcggtg
    39361 cgctgcgcaa gcgcggcctc aagcgcggcg tggccagcct gtgcatcggt ggcggcgagg
    39421 ccaccgcgat ggcgatcgag gtcgatgcct cggtggcctg cggctgaaac tgaccgacgg
    39481 gcacggtggc gctcatgagg cggccgtgcc tgctccaagc aaggacttct gaaaggacag
    39541 cagtgcaatg attctcaccc aggaacagga actcatccgc gactccatgc gcgccttcgc
    39601 gcaggagcgc ctggccccct tcgccgccga atgggaccgc aaccacacct tcccgcgcga
    39661 ggcgctgaac gagctcgccg agctcggcgc gctcggcatg gtggtgcccg aggagtgggg
    39721 cggcgccggc atggactaca tgagcctggt gctcacgctc gaggagatcg ccgccggcga
    39781 cggcgccacc tcgaccatcg tcagcgtgca gaactcgctg ccctgcggca tcctcaaccg
    39841 ctttggcagc gacgcgcaga aggaggcctg gctgaagccc ctcgcccgcg gcgagaagct
    39901 cggctgcttc tgcctcaccg agccgcacgt gggctcggat gcctcggcaa tccgcaccag
    39961 cgcggtgcgc gacggcgacg agtgggtgtt gaacggcgtc aagcagttca tcaccaccgg
    40021 caagcacgcc gacgtcgcca tcgtgttcgc ggtcaccgac aaggctgccg gcaagaaggg
    40081 catcacctgc ttcctcgtgc cggcgagcgc gcccggctac caggtcggcc gcatcgagga
    40141 gaagatgggg cagaaggcct ccgacaccac gcagatcctg ttcgaggact gccgcatccc
    40201 ggcggattcg gtggtcggtg cggaaggcga gggctacaag atcgcgctgt ccaacctcga
    40261 ggccggccgc atcggcatcg ccgcgcagtg cctgggcatg gcgcgcgccg cgctggaggc
    40321 ggcggtcaag tacgcgcagg agcgcgagag cttcggcaag ccgatcttcg agcaccaggc
    40381 ggtcaacttc cgcctcgccg acatggcgac ccagctcgag gccgcgcgcc agctcgtatg
    40441 gcacgccgcc agcctcaagg acgccggccg cccctgcctc aaggaggcgt cgatggccaa
    40501 gctgttcgcc tccgagatgg ccgagcgcgt atgctcggac gccatccagg tgcacggcgg
    40561 ctacggctac gtcaccgact tcccggtcga gcgcatctac cgcgacgtgc gcgtgtgcca
    40621 gatctacgaa ggcgcgagcg acatccagaa gctggtgatc gggcgcgcgc tggcgggctg
    40681 agcctgcacc ggcgcgaact gtgggccggc ctctccaggc ggggaggtcg gccttgtgtt
    40741 ttctgcggcc gcggaaacct tttcctgcga cgtcgtcgcc cgccgtcggc gatcctcccg
    40801 gcggccgtga cctgcgccac gtccacggcg gcccggttcg tgagaacatc cgctgcagga
    40861 gcgtcggacc gggccgtcga cgagtggctt tgtgcttgca ggcccgcgcg caccggaacg
    40921 attgaagaac gatcagcgag gcgagcgtca tggaagccgt gtcccctgca atgaattccg
    40981 ttacccgcga gctcatgcgg ccagccgagc cgcgtccggc gcaggccgcc gagcgcgagc
    41041 aggcggcgcg tgcgcaggag cccgcagcac gcgatgccgc ggcgagccag gccgcgcagc
    41101 cgagcgcggt ggtcacgctg agcgccgcgg cgcgcgccga gggtgcggca cagccggcgc
    41161 cgcccgcgca ggacggtacg gtcgaggcac gcgcggtcga gcaggcccgc gccgccgccg
    41221 ccaatggcga cgtgcgcaac aactactcgg cgcagcgcgc gctggcctcc tacgaggcca
    41281 tgtcgcaggt cggcgccaac aacgccgccg cgcgtccgag ccagcccgag caagccgtcg
    41341 cgccgggcca gcgtgagccg ggcgtgctgc gcacctgagc cgcggcagcg ttgcgcacgg
    41401 ccgcggcggg ttgggcgccg caggtcgggc gtcgactggc tagcactgag ggccgaccat
    41461 catgtccatc cagggtctcg gttcatccgc ctccgcagct tcctggctcg gcgggcaggt
    41521 ttcgcgcgag caggcgcggc gcagcgccga acagctcgac gcgaaggcgg ctgcgctcgc
    41581 ggccgaggcg gcgagcgcgc gcgacgaggc cgacaccgcg cagcgccgcg ccgacgagct
    41641 ccagacccag gccgggcagg cgcgcacgcg cgcggagctc ggcaagcagg cggtggcttc
    41701 ggtgcgcggc atggaccgtg cggcgcaggc cgtatccgcc gcggtcggac gcgtgggcga
    41761 ggcggtcgca gccgagcccg ctcagggtgc gtccgcgccg gcagccgcgg gcgtgcgggc
    41821 aggcgagtcc gccggcgccc agtccgcagg cctgtacacc gccgcggctg ggatccggcc
    41881 tgcgctctcc gtccagcccg ggcagctcgt cgacctgaag gtctgagccg cgtgcggcag
    41941 gcgtcgcgtc cccgtgcccg cgctcagccc ccgtcgtgct tcgcagcgaa ctcctccgcc
    42001 agctccggat attcctgcct gagcgtgtcg ccgccttgcc gccacgccgc gcagccgccg
    42061 acgaagccga ccgcgcgccg gtcggtccat ttgcgcggat cgggctcggc ggcgaactgg
    42121 cgggcgatca gcgtcggcca gattgcctgg gtataggtgt tgccgacctg cacgagcagg
    42181 tcggtgaggt gggtgcagcc ttgcacgccg cccacgcgct cgcgcacctc gcgcatgaag
    42241 cccgcgccga tctgcaatcc gaccagacgg cgataggcgg cctggctttc cggacaggcc
    42301 gcccagggca cggtctgcat ccgcgccgcg acgtcgtgga tcatcgcgtc gtcgtcgatc
    42361 agcaccgcga tcgtgatgtc gtggagggac tgcccgggtc gcaccatcgg acgcgagcgg
    42421 aaaggcatgt cctcgccctt ctcgtcgatc accgtcgcct cgatttccca cagcccgtcg
    42481 cggcgccgaa aggcctcgca gacgatgcgc cgcgtgtgca cccgttcccg ttcgctgctt
    42541 ccgagcatgt cttccaccca ttctccgtcg tgccgccgcg accagtgcgc ggcggcgcct
    42601 atactgccgt ggtcaggcgg tggacgataa caagagacgg aggagggtga aaagatggat
    42661 gtcgaacaat tcatgcaagg ctacaagaag gcctgggagg agcgcgacga ggcgcagttc
    42721 tgcgccctct tcgcgaccga cggcgaatac cacaacacgc ccttcgcggt gcagcgcggc
    42781 catgcgcagc tcgccgccta ctggcagcgc gtgaagctgc aggaggatgt gcaggtgcgc
    42841 tacgaaatcc tcgccagtgc gcctgccggc ggcgtcgcgc actggcacgt cacctaccag
    42901 gtggcctcgg aggagctgtt ccgcatctgg gcgcagtcga ccggcaccaa cctggtcgcg
    42961 cgcaagcccg gcgacccgct gccgcgcatg gtgctggacg gtgtgctgaa ggcggagttc
    43021 gacggcgacc tctgccggcg ctgcgacatc tggtggcaca gcatgccgat gcaggcgtga
    43081 gtgctgcgga agcggttccc gcccgcacgg caaagccgtc ggcacacagg gcgccacccc
    43141 gctggactcg agcctgcgag gtgggtcgtc acctgtcctt cagcaagccc tgcggcgacg
    43201 cgcggcgatg ccgagcagcc cgatgccgag gagggcgagg gcgcctggtt cgggaatcgt
    43261 aaccggaggc gcggacgaaa tcgccccgac ggcgtcgatg tcggcgccga ccgtcacgcc
    43321 tgccttgtcg ccttcgttca ggtcgtcggt caggcggacg aaggagaaga agtcggtcag
    43381 gccgaagccg aaggcgtcga tatcgatacc ggaggtggca ccgaagacct tgccgacgcc
    43441 gtaccaggtc gagccatcct tgctgatgtc gacgaaggtg tcctcgacgt cgggaccgat
    43501 ctcgaatatc cacaggtcga gggcgttatt gccgctgccg gtcaacgagt tgtcggtgaa
    43561 tcgcaggacg atccttccgc ccgcacccag gctgacatat tccggatcct gcccctccgg
    43621 atagtttggt acccccaggg cctggctgct gtcctggtag ggtgcggtgg gcacgttccc
    43681 accgccaaag gacggggtgt aactgacgac tgcgtctgcg aacgacgcag cgcctcccgg
    43741 gaactcgact cccttgaaga gggctgcgct cgaactcgcg ctcgcaagaa cgccgacaca
    43801 cagcgccagg ggcttgaggc ctgaaaggaa ttgccgcgtt ctgctcatga tggctttctc
    43861 cggtcggaca gcgacccgaa acttcaagca gaatcgatgc cagttgataa aaatcgttta
    43921 ttttcaggtg ggtgggcagg cttgcgaaag caaggcggag cggggtgtaa aaaattccga
    43981 cacccctggt gccggacatc ttgccgacgg caatcggcca gaggccctca tggccgcgcg
    44041 cactgatcct ccttgtttcc gcgcacgcgg ttgcctcccc cggtgggccg gcgctggttg
    44101 gacttgcact gaaggttgcc gtcgacccgg ttgtgagcga tgcggagcgc accgtggttg
    44161 gcgaagagct gaacgtcgcc gccgaccgtg accgagtcca gcctgaccgc cccgctccgt
    44221 tcgagctgga tgttgtcacc cacgcgcgag ctggcgacca tcgagatctg acgggcgtcc
    44281 tcggcctgaa gcttgccttc gatccggacg ccgcgagcgc tcagggtggc cgcgcggccc
    44341 accacgacgt tgccttcgat gcgcgtaccg tcgagtgtgc aggtcttgcc ggagggcacg
    44401 cgcaggtcgc cgtcgatcga cacatggccc atgcgaccgc tgcagtcgac cgtgtcggcg
    44461 tgcgcgggcg tggtgaggag ggtggcgcac agcaggaggc tggcgacatg caaggcggtg
    44521 gtcatgtttg gatcctgtcg agggaggagg gcaggattgc agcgccgacg tgccggatcg
    44581 gttgccgatt ctagaggccc ggcccggggc gacgtggcgc cgagtcgtaa cgggatgcga
    44641 tcggctttac ggtacgtgtc ggcgagctct ctccaggggc tggatcgcgc gatcgggggg
    44701 cgaggctaga atgcgcgtga cactgcttcc caggcgccgc catgcacaag actctcgcca
    44761 ccttttccga cctgaacacg ccgcccgttt tcgacttccc ccgccccgag cgtctcgtcg
    44821 cgggcaaccc gcagcgcgcc acgtggaccc gcttcgagcg cgacggcatg tccgccgggc
    44881 tgtggggctg cgagccgggt gcgtggcgga tcgcctttgc cgacgacacc gacgagttct
    44941 tccacgtgct ctcgggccgt atccgcatca ccgacgaagc cgggctcgcg cgcgagttcg
    45001 gggcgggcga ggcgtgcgtg atcccggcgg gcttcaaggg cgtgttcgag gtgctggaga
    45061 cggtgatgaa gcactatgtg ttcgtgaagc gcggggacat gcgctgagcg ctggcggggc
    45121 ggacactcgc tcccgccgtc cccgcacagg ctccctcacc cttcccggtg atccaggagc
    45181 cgtttcttca gcgccatgtg ctcgcgcagg acctggccat aggccacctg gagatcgccc
    45241 acgacccgat ccagcaagtt cagcgcttcg gtccgcttcg ccgcagtcgg ctgctcgccc
    45301 gcgaagatcg cgcccaggcc gacgagtgcg cagcctcgcg ccgcattcgg gagcgggcgg
    45361 gcgccgtcga ggagcacctt gcgcatgaat tccgagcccc gggtgtattc gacgatccgc
    45421 gtgatgaagc tgccgaacag gggatccttg cggaagtcct gcagggcgtc gagcttcagg
    45481 cgcagctgcg cccagaacag catgtcctcg ccgatcttct tcagcacggg atgatccccg
    45541 tccaggggga cgttcgcgtc ttcgaccagt cctcgatagc gctgaaagca ttcgaggtag
    45601 ttctgatgca ctttctcgaa gtcgtcgagc gcggggccga cgaaatcctc gtagagccgc
    45661 tggtcggagt gctggcgctg ctcgaccagc cggatgcact cgccgaccat cctgcccacc
    45721 agctccacga gcgcgtcggc ctcgccccgc gcggacgacg ttccctgcgt gccttcgctc
    45781 tgctgccggg cgacggcgac gctgaccgcc gcggccagct cgtcggtcgt cctgaagaag
    45841 ctcaccaccc ggtcgcggca aagctccgtg cgcagggatt cgatgcgctc gaggtcgcgg
    45901 tccatgagct tcctggacca cggcgcgtcc tcgtgcagca ggaagagcag gcagggcttg
    45961 cggcagcgct cggcctggcg gaactccagc tcggtgatgg agcgctcctg ctgcggcggg
    46021 atgtagccgt agctccaggc gaagagcccg atgtagaggt cggacgcggc cacgtcggcg
    46081 aggcattggt cgagggggcg ctggtcggag gagacgtagt cctccatcgc caccacgtcg
    46141 tgccccatct tgcgcagcac ccggtagacc gccgcgcgtg cctcggcgag atccttgtag
    46201 gtcgaggaca ggtagatctt cgccatgcgt cgcctcctgg ggatgtgtgc cgcgcgcccc
    46261 ccggcgagcg cgtatggatt gccgggggcg agggccgatg agttcagcgt agtcggggcg
    46321 cgcttcgtgc gcgagcggcc tgcttgccgt gccctgctcc gcctggggcc tgcttctcgg
    46381 gcggctcact ccccggcgtg caccgcggcg aacttgcgct ccatttcgcg ccgcatcgcc
    46441 cggcgcactt ccgctgcggc gaagcgcctg cgttcatcgg gcgtctgcgg cgacagcgcc
    46501 ggcaccttcg tcggccggcc ttcgtcgtcc acggcgatca tcgtgaagaa gcagctattg
    46561 acgtggcgca cgaccttggc gcggatgtcc tcggcgacga ccttgatgcc gacctccatc
    46621 gacgagttgc cggtgtggtt gaccgaggcg agaaaggtga ccagttcgcc gacctggatg
    46681 ggctggcgga acatcacctg gtcgacgctg agcgtgacca cgtagtgccc ggcgtagcgg
    46741 ctggcgcagg cataggcgac ctggtcgagc agcttgagga tggcgccgcc gtggaccttg
    46801 cccgagaagt tcgcggtgtc gggcgtcatc aggacggtca tggtgagctg gtgggcgggg
    46861 aggtccatgg cgctgtctcg tgcgagtgag tggggagcgg cccgcgtcgg tccgggcagg
    46921 cgcgcgtcgg tgccgcaggc gggcggcgtg agccggggtg gggcagtgtg cgccgccgac
    46981 caggcggggc gcaaggcggc cgccaaggcg gtgatcgtcc ccgcgcaggg gcgttcgcgg
    47041 gcgcacccac ggatcctgct tgttccgtgc gcgcccggtc tggctacggc gccaaccctg
    47101 cgcccatccg gtatgcgctc ggcgtcaccc ccgcccactc ccggaacgcg cgcgcaaagc
    47161 tcttctcgct gtcgaacccc accgcggcgg cgatctgctt gaccggcttc gtcgtctgca
    47221 gcagcagctt caccgcgtgc tcgcgtcgcg ccgcgttctt caggcgctgc agcgacaccc
    47281 cttcttcctt gagctggcgg tgcagggtgc gtaccgacag gttgagctgc gcggcgacct
    47341 cctcggcggt gtgggcggcg gcggggttgg cggcgagcac ttggccgacg ctgtgcacca
    47401 gcaggcggtc gcggcggtat tgcagcacgg taaggggcag cgcgcgctgc agcatggcct
    47461 gcagcgcctt ttcgtcgcgg cgcaccggca gggcgagata gcgcgcatcg aagcggatgc
    47521 cggcggtcgc tgcggagaaa cgcgccgggc cggtgaagag gtaggtgtag gcgtcggcgt
    47581 gggccggtgc ggggaagggg aaggcggcct ctccgagcgc gatgcgcgaa tcgaccagcc
    47641 agcaggcgta gccgagcagg tagcgcagcg tgctgaccag gcagaactcg cgcagctcgc
    47701 cgagttcggc gtgttcggcg acgcggatcg tggccgtgcc gccgcgttgc gcgagctcga
    47761 agacgatgtc ctcggtgagc aggcggtggt ggcggcacca gcgcttgagc gcgacctcca
    47821 gggtcggcga gctcagcgag gcgcggcaca gcatgccgta gctgccccag ggcaggcggc
    47881 gcgagaacca gcccagcgcc tcgtcgtcga gctcctgcat ggccaggccg gagagcagct
    47941 ccatctgcgc cgcggtgacg cgcgcggcgg gatcgtccag caaagcgggc gggatctgcg
    48001 cctgcgccag cgccctggcc ggatccatgc cccgcagccg atacccggcg gcgatcgcgc
    48061 ggatgaaggc gatcggcgtg gcggcgcggc cgcgggtgag ctcggcgggt gagggggcga
    48121 ggatcttcat gtgccggaat gctagcccgc gtggcacgaa ttgcaacctt gatggcactc
    48181 gtcgggcacg cagggcgatt aatctcgctc catccgcggg caggcgacgt ccataatgga
    48241 ttttccgcgt gggtccgcca cgccttgccc gctgcgccag gacaacctcg agaaggagac
    48301 accccatgaa cgtgcccagc ctgaacttca acctcggcga gaccatcgac gccctgcgcg
    48361 acaccctgca ggcgttctgt gccgcggaga tcgccccgcg tgcggccgag atcgaccgca
    48421 cgaacgagtt ccccgccgac ctgtggaaga agctcggcga cctcggcgtg catggcatga
    48481 cggtgagcga ggagtacggc ggcaccgaca tgggctacct cgcccacatc gtggccatgg
    48541 aggagatctc gcgcgcctcg gcctcggtgg gcctgtccta tggtgcgcac tccaacctgt
    48601 gcatcaacca gatccgccgc aacggcaccg aggcgcagaa gcagaagtac ctgcccaagt
    48661 tgatctcggg cgagcacgtg ggcgcgctgg cgatgtccga gcccaacgcc ggctccgacg
    48721 tggtgtcgat gaagctgcgc gccgaccgca agggcgaccg cttcatcctc aatggcagca
    48781 agatgtggat caccaacggc ggcgacgccg acaccctggt ggtctatgcc aagaccgacg
    48841 tcgccgcggg gcccaagggc atcaccgcct tcatcatcga gaaggggatg aagggctttt
    48901 cccacggcac ccacctcgac aagctgggca tgcgcggctc caacaccttc ccgctgttct
    48961 tcgacgacgt cgaggtgccg gtggagaacg tgctcggcgg cgaggccaac atcggccgcg
    49021 gcgtgcaggt gctgatgagc ggcctggact acgagcgcgc ggtgctgtcg ggcggcccgc
    49081 tcggcatcat ggcggcgtgc atggatgtgg tcgttcccta catgcacgag cgcaagcagt
    49141 tcgacacccc gatcggcgag ttccagctca tgcagggcaa gatcgccgac ctgtattcca
    49201 cctggagcgc ctgccgcgcc tacgcctatg cggtgggtca ggcctgcgac cgcgccgatc
    49261 acgcgcgcac gctgcgcaag gacgccgccg gcgtcatcct ctacaccgcc gagaaggcca
    49321 cctggatggc tggcgaggcg atccaggcgc tgggcggcgt gggctacacc aacgaatacg
    49381 ccaccggccg cctgtggcgc gacgccaagc tgtacgagat cggcgccggc accagcgaga
    49441 tccgccgcat gctgatcggc cgcgaactct tctccgagac ccgttgagcg gagccgcccc
    49501 catgagcgtg atcaaatccg gcatcaatac ccgcagcgcc gacttccagt ccaacgccgc
    49561 cgccatgcgc ggcctggtcg gggacctgcg cgccaaggcc gccgaggtca gcctcggcgg
    49621 cggcgaggcg gcgcgcgcca agcacaccgc gcgcggcaag ctgctgccgc gcgaccgcgt
    49681 cggccacctg ctcgaccccg gcacggcctt cctcgagatc ggccagatgg cggcctacgg
    49741 catgtacgac aacgacgcgc ccagcgccgg cgtgatcgcc ggcatcggcc gcgtgcaggg
    49801 catcgaatgc atgatcgtgg ccaatgacgc cacggtgaag ggcggcagct acttcccgat
    49861 gacggtgaag aagcacctgc gcgcgcagga gatcgcccag gccaaccgcc tgccctgcat
    49921 ctacctggtc gactcgggcg gcgccaacct gccgacgcag gacgaggtgt tccccgaccg
    49981 cgaccacttc ggccgcatct tcttcaacca ggccaacatg tcggcccagg gcatcccgca
    50041 gatcgcggtg gtgatgggct cgtgcaccgc cggtggggcc tacgtgccgg cgatgtcgga
    50101 cgaggcggtc atcgtcaaga accagggcac gatcttcctc ggcggcccgc cgctggtgaa
    50161 ggcggccacc ggcgaggtgg tgagcgccga ggacctcggc ggcggcgacg tgcatacgcg
    50221 catctcgggc gtggccgact acctcgccga gaacgacagc cacgcgctcc acatcgcgcg
    50281 ccgcatcgtc tccaatctca accagcgcaa ggaggtcgag ctggcgctcg ccgacagcga
    50341 ggagcccgcc tacgaccccg aggagatcta cggcatcatc cccgccgacc cgcgcaagcc
    50401 ctacgacgtg cgcgaggtca tcgcgcgggt ggtcgacggt tcccgcttcg acgagttcaa
    50461 gccgcgctac ggcaccaccc tggtcaccgg cttcgcccgc ctctacggct acccggtggg
    50521 catcgtcgcc aacaacggca tcctgttcgg cgagtcggcg cagaagggcg cgcacttcgt
    50581 cgagctgtgc ggccagcgtg gcatcccgct gctgttcctg cagaacatca ccggcttcat
    50641 ggtcgggcgc aagtacgaga acggcggcat cgccaaggac ggcgccaaga tggtcaccgc
    50701 ggtggccacc gtccaggtgc ccaagatcac catgatcatg ggcggcagct tcggcgccgg
    50761 caactacggc atgtgcggcc gcgcctactc gccgcgcttc ctgtggatgt ggccgaacgc
    50821 gcgcgtcagc gtgatgggcg gcgagcaggc cgcgagcgtg ctctccaccg tgcgccgcga
    50881 cggcatcgag gccaagggtg gcacctggag caaggaagac gaggaggcct tcaaggcgcc
    50941 gatccgcgag cagtacgagg tccagggcca cccctactac gccaccgccc gcctgtggga
    51001 cgacggcgtg atcgaccccg cgcagtcgcg ccgcgtgctc ggcctgtcgc tgtcggccac
    51061 gctcaacgcg ccgatcccgc agacgaagtt cggcgtgttc cggatgtaat gcagggaggc
    51121 gaggtctaag atggctatat ggatagccat ttaaggaggc gcagatgatc tcgattgccg
    51181 atgcgaagaa ccgcttgccc gcgctgatcc atcaggccga agcgggtgag ccggtcacca
    51241 tcacccgccg cggcaagccg gtggcggtgg tgcttgcggt ccaggaatac gaacgcatgc
    51301 gcgtcgcgac gaccgcgcgc ccgtcgttct gggatgtcgt gcaggaggtg agagcgaagc
    51361 tcgctgccga ggatgcgttt cctgactgga cggacgaaga gatcgacagc tggcgcgaca
    51421 ggacgatcta cgagccgcgc tgcgatttca gcggacccga atatgactgg gccgggggcg
    51481 ttgcagacga ctcggaaggg cccgatgtga aacaagagcg tgcgtgatgg gggtgtcggt
    51541 tctgctggat accaatgtgc tgtccgaatt gctcaagccg cgggttgatc ctggggttgt
    51601 gcgtcgtttt tcgcgtgatg gaaacgactg cgcgatcgcg tcggtcgttt ggcacgagtt
    51661 gctgtgtggc gccttgcgcg ccccgagtgt cgggcggggg gagatgctgg tacgggcttg
    51721 tcgtgacatt gtcatcggct ccggcatgca gatattgccg tacgacgaga ctgcagccac
    51781 ctggcacgca agagagcgtg cccgcctcct tgggctcggg cggccgcagc cctacccgga
    51841 ttgccagatc gccgccatcg ctgccacccg gaacctgacc ttggtcacgc gcaatacgcg
    51901 cgacttcgaa tgcttcgacg ggctgagact ggagaactgg ttcgaagccg gaaaggactg
    51961 aaacgcccct tgaggcgagg agacacgatg tacgaaacat tggaaattca acggaaagcc
    52021 ggcgtggcga cgatctggat gaaccgtccg gacgtgcaca acgccttcaa cgcgcagctg
    52081 atcgccgacc tcacgacggc ctgcatcgaa ctcgatgccg acgacgcggt gcgcgcggtg
    52141 gtgctcgcag ggcggggaaa aagcttctcg gccggcgccg acctcaactg gatgaaggcc
    52201 gccggcgagg cgagcgaggc ggagaacttc gccgatgcga tgaagctcgc cggcatgctg
    52261 cgcaccctgg ccgagatgaa gaagcccacg atcgcgcgcg tgcatggcgc ggcgctgggt
    52321 ggcggcatgg gcctggcgag cgcctgcgac atctgcatcg ccggggacaa ggccgtgttc
    52381 gccacctccg aggtcaagtt cgggatcatc ccctcggcga tcagccccta cgtgatccgc
    52441 gccatcggcg agcgccagtc ctatcgctac ttccagaccg ccgagcgcat cggtgcggcg
    52501 cgcgccgccg aactggggct ggcgcacgag gcagtggcga ccgatgaact ggacgccaag
    52561 gtgagcgaag tggtcgaggc cctgctgcag ggcgggccga agtcgcaggc cgcggccaag
    52621 gacctgatcc gcgcggtggc caaccggccg gtgagcgacg cggtggtgga agacaccgcg
    52681 cgccgcatcg ccagcctgcg cgccaccccc gaggccaagg agggcctggc cgccttcctc
    52741 gacaagcgcc ccgcagcctg gatcgcacag ggctgaacgg tgcacggtgc gcgacctgca
    52801 tccgtcgcgc gcaatgaagg gtttgcagga ccggggagac cgccatggac gcctatgcct
    52861 ggagcagctg gcccaccgag ctcaccgcgt tgctcgactg gagcggcgtg ccgctcgaca
    52921 tggcctcgct cgccgcgctg gcggcgggcc tgggctgggc gagcgggctg cggctgtatg
    52981 cgctggtgtt cgtgctcggt gcgcttggcc gcttcggcgg cgtgcagctg ccgggcgggc
    53041 tggaggtgct gactcacccg ctgctgctcg gggtgtccgg ggtgatgctg ctggcggagt
    53101 tcttcgccga caagctgccc tggttcgatt cgatgtggga cgcggtgcac accttcatcc
    53161 gcatcccggc aggcgcggcg ctggcggccg cggtgatggg cgaccaggcc ggcgcagtgc
    53221 agcttgcggc ggcgctggcc ggcggcaccc tggccgcggg tgcgcacttc gccaaggcgg
    53281 gggcgcgggc ggcgatcaat acctcgcccg agccggtaag caacgtcacc acctcgctcg
    53341 gcgaggacgc gatgttcgcc ggcgggctgt ggatgctgtt gcaggagccg ctgtggttcc
    53401 tggt
//
LOCUS       DAOTIN010000011        52639 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_630_length_52639_cov_8.188955, whole genome shotgun sequence.
ACCESSION   DAOTIN010000011 DAOTIN010000000
VERSION     DAOTIN010000011.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 52639)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 52639)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52639
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_630_length_52639_cov_8.188955"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            336..611
                     /locus_tag="P5537_03080"
     CDS             336..611
                     /locus_tag="P5537_03080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011238085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system CcdA family
                     antitoxin"
                     /protein_id="HRV77057.1"
                     /translation="MEGSMPATRSTQRARTHSSGKRATNLSLSSDVLEAARQLDINIS
                     QVCDAYLRELVRREQARKWREDHADFIAAYNATVEAEGLPLEAWRNF"
     gene            611..928
                     /locus_tag="P5537_03085"
     CDS             611..928
                     /locus_tag="P5537_03085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011238086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CcdB family protein"
                     /protein_id="HRV77058.1"
                     /translation="MARFDVYANTGGHADTTPYLLDVQSDLLDALDSRVVIPLRSLAH
                     FPKIRLPARLTPVLTVEGTDCLLETPKMGAVPLRALKSPVTSLAHAQEQITAALDFLF
                     QGY"
     gene            complement(1067..1648)
                     /locus_tag="P5537_03090"
     CDS             complement(1067..1648)
                     /locus_tag="P5537_03090"
                     /inference="COORDINATES: protein motif:HMM:NF017496.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Uma2 family endonuclease"
                     /protein_id="HRV77059.1"
                     /translation="MQSQPYRLLDESEYLTLEASSPVRHEYVAGEIFAMTGASIRHNI
                     IAGNLYTALRTHLRGTPCRALMEGVKLYLKKERSYFYPDVMVTCESRLLELDAQMQIV
                     DSPPLIIEVLSPSTEGIDRREKLRAYRTLPSLKEYALVSQDECKLELYRRRGDIAWDI
                     ITFEPGDAVEFASVELQMPIADVYFEAGVACSG"
     gene            complement(2019..2297)
                     /locus_tag="P5537_03095"
     CDS             complement(2019..2297)
                     /locus_tag="P5537_03095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HRV77060.1"
                     /translation="MSWDVRQTRRFARVYKKLHDNMLAEVDAAVEAVACNPDSGEKKK
                     GDLAELWVYKFRCLGQLYLLGYTRDGGVRLVYLEAVGPHENFYRDLKR"
     gene            complement(2294..2527)
                     /locus_tag="P5537_03100"
     CDS             complement(2294..2527)
                     /locus_tag="P5537_03100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77061.1"
                     /translation="MSTVSVRIDESLVSAARAAAKAEFRTVQGQVEFWAKVGRAALDN
                     PDLPASFIAESLMSMAEPREDSTVFVPRSTAKA"
     gene            2815..3096
                     /locus_tag="P5537_03105"
     CDS             2815..3096
                     /locus_tag="P5537_03105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011238085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system CcdA family
                     antitoxin"
                     /protein_id="HRV77062.1"
                     /translation="MRMEMAMPATRSTQRMRTGSSGKRAINLSLSSDVLDAAKQLDIN
                     ISQVCDTYLRELVRREQARKWREDHAEFIAAYNATVEAEGLPLEAWRSF"
     gene            3081..3413
                     /locus_tag="P5537_03110"
     CDS             3081..3413
                     /locus_tag="P5537_03110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011238086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CcdB family protein"
                     /protein_id="HRV77063.1"
                     /translation="MEKFLMARFDVYANTGSHADTTPYLLDVQSDLLDGLDSRVVIPL
                     RSLEHFPKVRLPARLTPVLTIEGKDCLLETPKMGAVPLRVLRSPVTSLARAQEQITAA
                     LDFLFQGY"
     gene            complement(3427..>3842)
                     /locus_tag="P5537_03115"
     CDS             complement(3427..>3842)
                     /locus_tag="P5537_03115"
                     /inference="COORDINATES: protein motif:HMM:NF017496.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="Uma2 family endonuclease"
                     /protein_id="HRV77064.1"
                     /translation="LRGTPCRALMEGVKLYLKKERSYFYPDVMVTCEPRLLELDAQVQ
                     VVDSPVLIVEVLSPSTEGIDRREKLRAYRTLPGLKEYAMVSQDECRVELHRRRGDIGW
                     DIITFEPGDTVELASVELALPIADVYFESGVACSA"
     assembly_gap    3843..3942
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(3944..4504)
                     /locus_tag="P5537_03120"
     CDS             complement(3944..4504)
                     /locus_tag="P5537_03120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Uma2 family endonuclease"
                     /protein_id="HRV77065.1"
                     /translation="MALPQPTAPFTAEDYLRWEAGQPDKHEYYHGETFAMGGASRRHV
                     TISLNVAAALDEALEGSPCRTYMADMKVQAAADEAYFYPDVLVTCDPADHRADQFMRA
                     PTLIVEVLSPATAAYDRGEKFAAYRRIPSLRDFVLIDPDLRRIEHYRRSQDERWELQD
                     IAPEQALVLESLEVSVPWQKVFRNAD"
     gene            4554..5138
                     /locus_tag="P5537_03125"
     CDS             4554..5138
                     /locus_tag="P5537_03125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HRV77066.1"
                     /translation="MNAKPRHVERALHERVEIVPYDPAWPGLFAEEVARLRAALPADL
                     IGRIEHFGSTAVPGLAAKPIIDMLVEVRTMEDVAQRIAPLLQAQGYEFFWRAPEHGLP
                     GMNYAWFIRRDAAGRRTHHIHFLETGSSEWERLLFRDYLRAHPEAARAYGELKQRIAA
                     EHPDDRVAYAKAKTRFVRAAMQAARAEVGGPRRV"
     gene            complement(5347..5634)
                     /locus_tag="P5537_03130"
     CDS             complement(5347..5634)
                     /locus_tag="P5537_03130"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77067.1"
                     /translation="MKMKAVTILAMALVFGTGALMTPTDSMAQSSEQRWGSGHGNDRN
                     KAREAGKKAAEARKSGQNKSGRMTAAEKEAYRDAKDKGLEEDFKRGYRDGQ"
     gene            6187..7218
                     /locus_tag="P5537_03135"
     CDS             6187..7218
                     /locus_tag="P5537_03135"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77068.1"
                     /translation="MTAPIQGRRPFAVWLIVLLLLAYGLLGPLLLVAGSGSIATITEV
                     RRTGGAEPQWFHRYWWVVAYEFTAADGTLHGGHTRTLAYDTGPRGYAKVEPVLYLAAA
                     PWLNVLRKEAGVHAGTVAVLGAALLILWLTRARQPQRGAAVPAAGKRTAGGRRSRASA
                     TSGAATAMTVEQSRRWLLGYRRHSRLYAWLFFAAVIPVVVLVIWLEVGELDEEVLGSV
                     AFFIVVFLALALGSRRQTSAAWRAVVVDKQRTERGAGGTLVLQLERGERRTLRVSPPL
                     FDYFAPGDAVFKLDGFEWPEKWSPDEGRRVCIACGGVVELAEPMSACPRCGAPLPAHE
                     AMQALAPRA"
     gene            complement(7237..9360)
                     /locus_tag="P5537_03140"
     CDS             complement(7237..9360)
                     /locus_tag="P5537_03140"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77069.1"
                     /translation="MAHPNRPAQSRRPRLALPARGLRARAWTLAGLAAALVFSPLACS
                     PLALARPAPDDLQWADDAAGNEAIKSWHNTAVEGINLTLRQFSEDEAVRKLVTDELRA
                     AGEVLQHNADAARQFWADLRRIGSRDELHALIERKGLRAHAANLVQDYADGLAGQGDA
                     VLRRIVAHSDAGVDLAGREALDLLQQAKAQLAKNGSLSKELNRKLADALAKLPSERAL
                     AGHRLLRNQFAVHGVSGFDMFTRGGMDTAFALLDINRIRKLETAEERAAAASGTIASY
                     GLETAANVGVRVLGGGLFLHGLVVSLSAAAVGEMLNEMILLHYDLENTALAEQQVAIA
                     ARANVLQGLLRTDELIKAGKLAEARSYLTKLRHFYQKRDEADDRILARLLEFDRHLDA
                     AADQLQANRIIAEARVHYDAGYGLARKGRQLRQAREHLLDASKILEDGHAVYPILRPA
                     LEHTRRVIGLVERLIAEAAPLQRVVLSGPEAARAGDWVSFSLLVVGGVPDFTVVGADS
                     MPAPGGAIANVRAPDTPGTHPLAFTVRDHLGRSVSAHTTLRVLAAADTPPPAADTSCE
                     GTVFDVQVTHADRSRTRFAFLLMPRDEVVRLARERAGKALQEHEIERVLTQTFRSSMP
                     DHESQAAIAAAMPKRCHALLSKRQLFIMWHGTRTETNAAGSTRYQAEFRNGYRVRTLV
                     EPTPEPAAAGRPVGGVPVGGGFAPR"
     gene            complement(9366..10028)
                     /locus_tag="P5537_03145"
     CDS             complement(9366..10028)
                     /locus_tag="P5537_03145"
                     /inference="COORDINATES: protein motif:HMM:NF019843.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77070.1"
                     /translation="MRPPLPAGARRRGLIAALLACVSIASATQAADAVDPAQLAEARA
                     AYQAAFEHYTRLVTTPGAKGDRAAALAAYREASTRYRALQARLEGAGRSAPGTPAPAA
                     PTPSSRPPLRTEGIAGIVSIDTDPTDPRARLEQDASAGAPRAQALLGLLALRGLGAQA
                     DPEAGIAWLRRAAAAGDADAMAMLADELDSGLWVEPDPARARSLRERAARLGSPLATW
                     GR"
     gene            complement(10025..10690)
                     /locus_tag="P5537_03150"
     CDS             complement(10025..10690)
                     /locus_tag="P5537_03150"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77071.1"
                     /translation="MHSDPVPAARPAPGITPGRDGVLRWVHEISLWKNPTVLITTAKV
                     LLLAASVPALLVGVLALVEGDGIGAALGSVAQVGGIVVGIVAVLLLIAYPLTAILQGG
                     RYCVVFEMDERGVRHTQLRKQFERNQAVAFVTVLAGIAAGSPQAAGAGLLAASRQSLH
                     TAFAKVRKVRIDERRGVIHLAERLTRNQVYAAPEDFAFVRDFILARCPRAAVSGHTGG
                     RDT"
     gene            complement(10748..12385)
                     /locus_tag="P5537_03155"
     CDS             complement(10748..12385)
                     /locus_tag="P5537_03155"
                     /EC_number="1.5.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004317135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004174 -
                     electron-transferring-flavoprotein dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein-ubiquinone
                     oxidoreductase"
                     /protein_id="HRV77072.1"
                     /translation="MERESMEFDVLIVGGGPAGLAAAIRMKQLAEAKGSELSVCLIEK
                     GAEIGAHILSGAVIDPRSLNELIPDWKEKGAPLTTAVTEDQVLFLSETGVRRVPPALT
                     PDCFENHGNYIVRLGNLVKWLGEQAEAAGIEVYPGFAAAEILYDESGAVKGVATGDMG
                     LNRDGTPGPHHQPGMELHAKYTLFAEGCRGHLGKQLEARFNLREGVDPQTYGIGIKEL
                     WEVKPEMHRPGLVVHTAGWPMDNRTYGGGFIYHLEDNLVALGFVVGLNYENPHLSPFD
                     EMQRWKTHGEVRKHIEGGKRLAYGARAIATGNLQSLPRLIFPGGGLIGDDAGFLNAAR
                     IKGVHAAIKSGMLAAEAAFDALAANRQRDALTAYPAAFRESWLYTELHKYRNFKPLMK
                     KGLWMGSFLFGMDQMLFRGKAPWTLHNSSDHDKLKPASECPKIDYPKPDGVLTFDRLS
                     SVFLSNTNHEEEQPCHLQLKDPSVAISVNLARYDAPEQRYCPAGVYEIVHEEAGPRLQ
                     INAQNCIHCKTCDIKDPTQNINWVVPQGGEGPIYQGM"
     gene            12573..12992
                     /locus_tag="P5537_03160"
     CDS             12573..12992
                     /locus_tag="P5537_03160"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HRV77073.1"
                     /translation="MSPNAKLIYTTRMPVRWGDMDAYGHVNNTVYFRYFEQTRVEWLE
                     LMGSRVSVEEPVGPVIINASCTFLAPVNYPATVVIKMYAGEPGRSSVMTWYELFVEGD
                     ERVYAEGAAKTVWMDMGTGKSAPIPDVVRALFAPPAA"
     gene            13073..15061
                     /locus_tag="P5537_03165"
     CDS             13073..15061
                     /locus_tag="P5537_03165"
                     /EC_number="6.2.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030729 - acetoacetate-CoA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetoacetate--CoA ligase"
                     /protein_id="HRV77074.1"
                     /translation="MYPTEQKPLWTPSPERIAAARVTAFRLAAAQRWGVALPDYEALH
                     AWSVAQPEQFWTSVWEGDGVGGGVIGTRGERVLVDGHRMPGAKWFPDARLNFAQNLLR
                     SRDAHDAIVFWGEERVKNRLSHGELYRAVAHFAAALKEQGVVAGDRVAAYMPNLPETV
                     IAMLAAASIGAIFTSASPDFGVQGVLDRFGQTEPKVLVACDGYYYGGKTVDVLGKLGE
                     IVSQLPSVKRVVVVPYVHAEHDLSHVPHARMYADFIAPFHFVDDIEFAQLPFDHPLYI
                     MYSSGTTGVPKCIVHCAGGALLQHLKEHKLHGDVKPGDRVFYFTTCGWMMWNWLVSAL
                     AAEATLLLYDGSPFAGDNQILFDYADAEHMTHFGTSAKFLDAAAKFGLKPRETHRLET
                     VRAMMSTGSPLVPEGFDYVYRDIKADLQLSSISGGTDIISCFVLGSPVLPVWRGEIQC
                     RGLGMAVDVWDDDGRPVRGEKGELVCSKPFPVMPIGFWNDADGSKYHAAYFDRFDNVW
                     CHGDFCEITAHGGLVIYGRSDATLNPGGVRIGTAEIYRQVEKLHEVVESLVIGQDWPP
                     QNPNDVRVVLFVKLREGVTLDDELTKRIRQTIRDNTTPRHVPAKVLQVADIPRTKSGK
                     IVELAVRNVVHGRAVKNQEALANPEALAHFRDRAELQG"
     gene            15076..15618
                     /locus_tag="P5537_03170"
     CDS             15076..15618
                     /locus_tag="P5537_03170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004332820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family protein"
                     /protein_id="HRV77075.1"
                     /translation="MLMNPKKSVLLVIDVQAKLAPFIHDNAAVVDACVWLARVADRIG
                     VPVVVTEHFPEKIGGTVEAVRAATAGAHYVGKQYFSAQADGCLEHTAVAGCEQVIVCG
                     TEAHVCVQQTALDLRRAGKQVFIVAEASGSRDPANRDLAFARMRGHGIEIVSREMVAF
                     EWLQRGGTELFREVNRDFIR"
     gene            15834..20657
                     /locus_tag="P5537_03175"
     CDS             15834..20657
                     /locus_tag="P5537_03175"
                     /EC_number="1.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004352 - glutamate dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_process: GO:0019551 - glutamate catabolic process to
                     2-oxoglutarate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-glutamate dehydrogenase"
                     /protein_id="HRV77076.1"
                     /translation="METRETGRLATQVDAVIEQIRARLPAEQAEGVCAFASRFFAQVA
                     PEDLEDLPVADLYGAVLSQWHFVARRKAGSKVRAFNPRLDEHGWECPHTVVEIAGEDM
                     PFLVDSITMEVARQGLTLHLIIHPVMNVARDAEGGFVRVAERAEQGEGIGFESIMHLE
                     VDRRTDPGDLAALQQGIERVLADVRAAVGDWNAMRERLAGITSGLDELPGGIDADEAQ
                     EVRAFLDWLAADNFVLLGCRDYALVESGEGNELRIVAGSGLGLLRGDGEEGQSRSFAA
                     LPPQLRAQAHLPHLLTVTKSNSRSTVHRPGYLDFVGVKTFGADGRVNGERRVIGLLAS
                     TAYSTSPRQIPLLRRKVEAVFERAGLLPGGHAAKALQTLLERYPRDELFQIDTDELHA
                     HAMGILRLGERLRTRLFVRVDPFERFVSCLIYVPREHYNTDQRERMQAVLIDAFKGSA
                     AEFDVQFSDSALARILITVRTPEGRIPAFDVREIEQRLIRAARRWEDELQQALVEQCG
                     EERGLALMRRYGEGFPAGYREDYSARMAVFDIEQMEALADDAALGLNLYVPLEVREGR
                     LALRLYHLGSPVPLSQSLPMLEKMGVKVMDERPSEIERQDGSTVWLHDFGLQFAGAEN
                     LNIHEVRPLFQEAFLAAWRGAAENDDFNRLVLLAGLSWREVAVLRAYARYMRQAAFTF
                     SLAYMEQTLAAYPQLARALLQLFRARFDPALAGDREAACAAQVAAIEAALDQVANLDE
                     DRILRQFLALIQATLRTNWFQRGADGAPKAYLSFKFLPAKIPNLPQPLPMFEIFVYSP
                     RFEGVHLRGGKVARGGLRWSDRMEDFRTEILGLVKAQIVKNAVIVPVGSKGGFVVKCP
                     PAEGGREALLAEGVACYRNFLRGLLDLTDNLVQGAVAPPADVVRHDEDDPYLVVAADK
                     GTASFSDYANQVSAEYGFWLGDAFASGGSVGYDHKKMGITARGAWEAVKRHFREMGKD
                     IQQQPFSVAGIGDMSGDVFGNGMLLSKQIRLVAAFDHRHIFIDPDPDPARSWEERARM
                     FALPRSSWDDYDRTLISQGGGVWPRSAKSIALSPEARAALDIQAGSLTPTELIRAILT
                     APVELVYNGGIGTYIKAASQTDAAVGDRANDAVRVNGGELRCKVFGEGGNLGATQLGR
                     IEFALAGGRINTDAIDNSGGVDCSDHEVNIKILLGGVIAEGELTLKQRNELLADMTDE
                     VGILVLRDNYAQTQVLSVTRARGVALLDEQAEFIRRLVQAGRLNRKLEYLPDDEEIAE
                     RKAAGGGLTSPELAVLLAYSKIELYDEVLASDVPEDPYIRTALERYFPAPLRERFPAQ
                     IQAHPLRREIISTHVVNSMINRVGPTFVSRLKAELGASPADVVRAYMATREVFGLVAL
                     WREIEALDNRIADAVQTELIQESGRLVQRGTLWFLRHRRWLADLQATIAHFSPGVAAL
                     AEGLADYVAPAYRAELDAAVARRVEQGVPEALAKRVAALEELYSALDLVEVAVEQGRD
                     EATVARVYFALGGELDLHWLGGQVSGLPADTRWQSLARGALRSDLSSLARELTSAALR
                     NAPAGADTQDVLRAGRERAAVPLERYQQLLAEIRGAPAIDMAMLSVLLRELRGMA"
     gene            20750..22402
                     /locus_tag="P5537_03180"
     CDS             20750..22402
                     /locus_tag="P5537_03180"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HRV77077.1"
                     /translation="MTKYVFVTGGVVSSLGKGIAAASLGAILESRGIKVTHLKLDPYI
                     NVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFTSAKMSKRNNFTTGQIYESVLKKE
                     RRGEYLGKTVQVIPHITDEIKAYVKRGAEGADVAIVEVGGTVGDIESLPFLEAIRQMG
                     FEEGRHGTCFIHLTLLPYIPTAGELKTKPTQHSVKELREIGIQPDILLCRADRSIPAD
                     ERRKIALFCNVMPEAVIECLDADSIYKIPGMLHDQMLDQIVCHKLDILARAADLSVWE
                     KLIHALENPRQTVDIGFVGKYVDLTESYKSLIESLNHAGMHTESKVKIHYIDSEDIER
                     DGCGVLASMDAILVPGGFGKRGTEGKIAAIRYARENKVPYLGICLGMQLAVVEFARDV
                     AGMDGAHSTEFERDTKYPVIGLITEWKDRSGKIEKRTEESDLGGTMRLGGQLCLLKEG
                     TLARSIYGAAEVMERHRHRYEVNNTLLARLEDKGLVVSGRAPVTDLCEMVELPADVHP
                     WFVGCQFHPEFTSNPRKGHPLFTAYVKAAIERKQAESSRSEA"
     gene            22399..23238
                     /gene="kdsA"
                     /locus_tag="P5537_03185"
     CDS             22399..23238
                     /gene="kdsA"
                     /locus_tag="P5537_03185"
                     /EC_number="2.5.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008676 - 3-deoxy-8-phosphooctulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-8-phosphooctulonate synthase"
                     /protein_id="HRV77078.1"
                     /translation="MNLCGFEVGLDKPIFLISGPCVAESEQMCLDIAGQMKEICAELG
                     IPYIFKASYDKANRSSGKSFRGHGMDAGLKMLEAVKKQLGLPVLTDVHTIEEIPLVAS
                     VVDVLQTPAFLCRQTDFIHAVAASGKPVNIKKGQFLAPGDMKNVADKAREANGGADTI
                     MVCERGASFGYNNLVSDMRSLAIMRDTGCPVVFDATHSVQLPGGQGTASGGQREFVPV
                     LARAAVAVGVAGLFMETHPDPAKALSDGPNAWPLPKMKALLSVLKDIDSLVKRQGFLE
                     TTL"
     gene            23394..24677
                     /gene="eno"
                     /locus_tag="P5537_03190"
     CDS             23394..24677
                     /gene="eno"
                     /locus_tag="P5537_03190"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011001079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HRV77079.1"
                     /translation="MSAIVDVIAREILDSRGNPTVEADVLLESGVMGRAAVPSGASTG
                     SREAIELRDGDKSRFLGKGVLRAVENVNTEIAEAIIGLDAEEQAFIDRTLIELDGTEN
                     KSRLGANAMLAVSMAVAKAAAEEAGLPLYRYFGGSSPMVMPVPMMNVINGGEHANNSL
                     DIQECMIMPVSMTSFREALRCGAEIFHHLKKIVDAKGYPTTVGDEGGFAPNVSGTEEA
                     LNLIQEAIVAAGYVPGQDVLLALDCAASEFYKDGKYELKGEGLSLTAEGFTDYLETLC
                     DKFPIVSIEDAMAEGDWDGWKILTERLGKRVQLVGDDLFVTNTRILAQGIEQGVANSI
                     LIKINQIGTLTETFAAVEMAKLAGYTAVISHRSGETDDSTIADIAVGLRAMQIKTGSL
                     SRSDRISKYNQLLRIEEDLGDTANYPGKRAFYNLR"
     gene            24775..25047
                     /gene="ftsB"
                     /locus_tag="P5537_03195"
     CDS             24775..25047
                     /gene="ftsB"
                     /locus_tag="P5537_03195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsB"
                     /protein_id="HRV77080.1"
                     /translation="MRWPILILIALVVLLQYPLWLGKGGWLRVWEVDRQLHAQREENL
                     RLEQRNAALAAEVNDLKSGNEAIEERARFELGLTRPGEIYVQIPQR"
     gene            complement(25077..25667)
                     /locus_tag="P5537_03200"
     CDS             complement(25077..25667)
                     /locus_tag="P5537_03200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HRV77081.1"
                     /translation="MSPESLPRAFPSSGQHSHHGARRRMLLAAAAGVAALLAGCSTTP
                     TPVASPAPPPRTTAPSGHYFSLEGEHQTQEMVLFALGLLDTGYRFGGRNPDAGLDCSG
                     MVAYIVEHISGRRLPHNAAQIAERTRPIEVDELRPGDLVFFNTLKRRHSHMGIYIGDG
                     RFVHAPNSRGRVRVERLANRYFAQRIDGARTLLASN"
     gene            complement(25809..26501)
                     /locus_tag="P5537_03205"
     CDS             complement(25809..26501)
                     /locus_tag="P5537_03205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305918.1"
                     /note="The SIMPL domain is named for its presence in mouse
                     protein SIMPL (signalling molecule that associates with
                     mouse pelle-like kinase). Bacterial member BP26, from
                     Brucella, was shown to assemble into a channel-like
                     structure, while YggE from E. coli has been associated
                     with resistance to oxidative stress; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIMPL domain-containing protein"
                     /protein_id="HRV77082.1"
                     /translation="MRAALATLATLTALQSAAAVAADTPAPPTVELSAEAGGAAANDL
                     AVAVLYAERSGTSAAAVAREVNRDIAAALELARAQGAVKVQSGNVSTWPVYGKDGQGR
                     ITAWRMRSELRLESTDTAAMSELVGKLQQSLALAHLTMEPAPETRRKAVADVTVDALR
                     AFETRAQLIADTLGRRYRIAHLAVGDHGLQPPPMPRMRAAVMAAEAAPAPLEGGESRV
                     SVHVSGRIELLD"
     gene            complement(26501..27055)
                     /locus_tag="P5537_03210"
     CDS             complement(26501..27055)
                     /locus_tag="P5537_03210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HRV77083.1"
                     /translation="MSIYALGDRRPSFGEGSWIAHNATVIGSVTAGRNVSIWYNVVVR
                     GDNDPITIGDDTNIQDGSVLHNDDGIPLTIGRHVTVGHMAMLHGCTIGDGSLIGINAV
                     ILNNAVIGKQCIIGANTLIPEGKVIPDRALVVGSPGRVIRTLSDTEVENLVVNAHNYV
                     DNARLYADRLCALEPSSVIAQPEQ"
     gene            27242..28087
                     /gene="rlmJ"
                     /locus_tag="P5537_03215"
     CDS             27242..28087
                     /gene="rlmJ"
                     /locus_tag="P5537_03215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2030)-N(6))-methyltransferase
                     RlmJ"
                     /protein_id="HRV77084.1"
                     /translation="MLSYRHAFHAGNHADVLKHLVLIELLDYYGRKDKPWYYIDTHAG
                     GGCYALDSEQAGKTAEAADGIGRLWGREDLPPAVASYVEAVRQFNPQGRLLFYPGSPA
                     LAMTRARVQDRLRLFELHPADFESLQRTFASEQERVQVRRADGFAALKSLLPPPSRRA
                     VVLIDPPYEVKDDYRRVVDTMRDAMRRFPTGTYVVWYPMLARTEARQLPERLAELGAE
                     SWLDVRLAVRDAPRDGIGMFGSGLYVINPPWVLPQRLEAALPWLVERLGVDGGAGFDL
                     EHHIE"
     gene            28192..28509
                     /locus_tag="P5537_03220"
     CDS             28192..28509
                     /locus_tag="P5537_03220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011765867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HRV77085.1"
                     /translation="MRQFAAERAWEPFHTPKNLAMALAGEAGEVIEHFQWLTAEQSMA
                     LPPASREEVAFELADVLLYLVRLGDVLGIDLADAARRKMVLDAQRYPVERARGRADKH
                     DRL"
     gene            28606..30186
                     /locus_tag="P5537_03225"
     CDS             28606..30186
                     /locus_tag="P5537_03225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter"
                     /protein_id="HRV77086.1"
                     /translation="MDLQHISDIERAAHQGRGEVFRLGMGVLFIVGVMFYSALSGSGE
                     GNLTLVMAAMIGGYMAMNIGANDVANNVGPAVGSKALTLAGALVIAAIFEAAGALIAG
                     GEVIGTIRSGIIDPDLIKDSDTFVWIMLAALLAGALWLNLATAVGAPVSTTHSIVGAV
                     LGAGMAAAGPAIVDWSTMGNIAASWVISPVLGGIFAAAFLYLVKRSITYQVDMAAAAR
                     RTVPLLVGLMAWTFASYLILKGLNRVWKVDFLSAMVYGAVVGALVFVVVRKVLHGNGG
                     IVANTKASVNRLFTVPLIFAAALLSFAHGSNDVANAVGPLAAIVDVVSSGGVVHKDAT
                     IPTWVMMVGAIGISLGLALFGPKVIRTVGSEITELDQMRAYCIAMAATLTVIVASQLG
                     LPVSSTHIAVGGVFGVGFLREYLKSNYDRMVAEIKAHHPEGDLAAIEAFIARFEKASI
                     EEKGQMLADLKERSKNADDPAHFSKGERKGLKKVYRRELVKRSQLMRIAAAWVITVPA
                     SALMAAVLFFMIRGMMLP"
     gene            30218..30577
                     /locus_tag="P5537_03230"
     CDS             30218..30577
                     /locus_tag="P5537_03230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3301 domain-containing protein"
                     /protein_id="HRV77087.1"
                     /translation="MSFVELLGFLALGAIVWYWFDSLKAREIGVDAARRACAREGVQF
                     LDETVVGQGLRLARDDDGRVVLRRGYAFEYSVGGDDRNAGSVVLEGREVVLVDVSAHR
                     LARRAVVIELHPRDPSA"
     gene            complement(30574..31227)
                     /gene="folE"
                     /locus_tag="P5537_03235"
     CDS             complement(30574..31227)
                     /gene="folE"
                     /locus_tag="P5537_03235"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HRV77088.1"
                     /translation="MSPPAHDPCGHDHPHAPRPDGVGIPRRGAFDAPAFEKAVGDLLR
                     ACGIAPDNAHTGRTAQRVRELWQRRLLGGYELDPAEVLGDGFEDARRDMVVIRGIAVH
                     GVCPHHLVPFRGVAHVAYLPGGRLHGFGRIARLVDAIGHRFTYQEWMTRDIADALMHH
                     GHAAGAACVIEAEQLCLLLGEDRRGDERVITQAFAGEFERSEQARSEFLRAIEERRR"
     gene            complement(31287..31883)
                     /locus_tag="P5537_03240"
     CDS             complement(31287..31883)
                     /locus_tag="P5537_03240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77089.1"
                     /translation="MIDMDAARAMLGRQAILLPDPVPSHALLDGKKEIGRGEYSIVID
                     KGDGERVYKVVSSPADYFLYTAEDRPRGPHFPIVYADHGVIGRAQSGYPFHLIEMERL
                     YPLVEGSPAAELSRRLIECYWSACAQWSRLGADMGRIALYHLTVDPLKIGDSLQEALR
                     ALSDFVEEYQVLPDILNANNLMMRADGTLVFSDPVFIA"
     gene            complement(31898..32677)
                     /gene="fabI"
                     /locus_tag="P5537_03245"
     CDS             complement(31898..32677)
                     /gene="fabI"
                     /locus_tag="P5537_03245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004318 - enoyl-[acyl-carrier-protein]
                     reductase (NADH) activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HRV77090.1"
                     /translation="MTPIINLEGKVGLITGIANEKSISTGVAEACAQAGAKLIITYQN
                     EKTRAFIEPVIHRLGVEDVFLLDVTRPETMDATFAAIEARHGKLDFAIHSMAFAKRDD
                     LHGRVVDTSADGFALAMDVSTHSFVRLAKKAEPLLEKAGGGALVTMTYLGSEKVIPNY
                     GVMGLCKAALEAATRYMAAELGAKGIRVNAVSPGPLMTRAASGIAGFDGLMAAAVERS
                     PMHALVTPEDIGALTAFLVSDAGRLVSGGVHFVDAGYNIMA"
     gene            32865..33374
                     /locus_tag="P5537_03250"
     CDS             32865..33374
                     /locus_tag="P5537_03250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD domain-containing protein"
                     /protein_id="HRV77091.1"
                     /translation="MTRNAYIFMDFDGVTHPWGEVEDFRCLPHIEAVVREFPEARIVI
                     ASDWRMLFSLPKLVARFSEDIRPQIAGATPHLLPKTGAELHGLREREAMAWLRQHGAD
                     PAEAAWCAIDDAPGNWLSRSRLVLTDFKRGFTAEDAVALRRMLQGFRDGVRNQVGQVV
                     HSLWARDSA"
     gene            33389..34159
                     /locus_tag="P5537_03255"
     CDS             33389..34159
                     /locus_tag="P5537_03255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77092.1"
                     /translation="MNPAEQTLPPDPLARHVDLATQRQAARLAEESFARLFRLSVAEG
                     DAARLKGVEQLRVDLADWVAAAADAEAQALRLALVLAGLDQWGLAWSRAFGLVAIPAL
                     TELIGALRTGLDEAAEARFLRHFEGIAAAEENAIDFKVELRRGLHLALWHASIATGHR
                     DEALRLAAELGSQLLALTRSMPVAGWRLVADALAFIQIRCLAEGLAAEGVAQEATQAL
                     FGALARELPAPQRDLVMAHSARAVMAWQQAGRASQQVH"
     gene            34159..34695
                     /locus_tag="P5537_03260"
     CDS             34159..34695
                     /locus_tag="P5537_03260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeQ family protein"
                     /protein_id="HRV77093.1"
                     /translation="MALKATVFKADIQVADMDRHHYADYSLTLARHPSETDERMMVRL
                     LAFALFADPALAFGKGLCADDEPDLWQRDLTGAIERWIDVGQPDDKWVRKACGRAREV
                     VLLAYGRALEVWWSGVRGRLERHGNLRVLELEREASAELGRLAERTMRLQFTIQDGHV
                     LVTNGRDTVSLEPRKLAG"
     gene            complement(34753..35637)
                     /locus_tag="P5537_03265"
     CDS             complement(34753..35637)
                     /locus_tag="P5537_03265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HRV77094.1"
                     /translation="MKLQSWTHHTTAGFTLRGHHSPPSGRPVLHFLHGNGLSSLTYAP
                     MLRHLSEHFDLFLSDVQGHGDSDHGSRFRGWNHAAEMAAEAWLAHAARFGAVPVHAAG
                     HSFGSVLTCLMLAHHPQAFSRGVLLDPVLFTPAMIGMMALSDLVGLASRNKLAAKART
                     RRHHWPDRATAHAGLHGRGVFRGWSEDSFQAYIDHALRDVPGGGVELKCRPTREAEIF
                     ASYPRRLWSSLERIEHPVLALHGRDTFAFARRSVTRWAAGKANVKCVQVEGGHCFMLE
                     HPQATAERVAAFLLDRPR"
     gene            complement(35686..>36356)
                     /locus_tag="P5537_03270"
     CDS             complement(35686..>36356)
                     /locus_tag="P5537_03270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HRV77095.1"
                     /translation="DLEGTELETRLGQWVIDHALGALERCRAAGLDIGVSVNIGPRPL
                     MQAGFVASVRSALERHPDIPPARLELEILESTALDDMVLAMDVLESCRRLGVRIALDD
                     FGTGYASLRHFRQLPFDRLKIDRSFVLDMLEDGEARAIVGAVVQLARTFGREVIAEGV
                     ETPAHAEALLDLGCRLGQGFGIARPMPVEHIPGWFSWQTHAPFADDAACASPGRCPPI
                     RSAR"
     assembly_gap    36357..36456
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<36457..39005)
                     /locus_tag="P5537_03275"
     CDS             complement(<36457..39005)
                     /locus_tag="P5537_03275"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HRV77096.1"
                     /translation="MRRILRTALLCVGLGIGSLDLQAQPGLDFGVYSSRPKALVEASW
                     QPFVDYLNTRLDGVEVRLHALDDAGLQRALAAGELELLLTNPAHFITLRSANPLSGAI
                     ATVVSDAGGQALNEFGGVILVRSGDKRLSALADLQGKRVGTTHANFLATYPAQAFEMK
                     AAGADPALLDMLTLQQSQDSVVDAVLDGRVDAGFVRTGLLEALSAEGRDLSGLRVLHP
                     LQHAGFPLHSSTRLYPEWPLVALRQADPALMRKVAALALGLEAGDPAARAARIHGFTI
                     PADYARVEEMLRELRLPPFDASPPFTWNDVWARYHETLFVLGLATLAIVLLLARLAQR
                     NLALSQANAAARRLAAEVELDRHHLRNVVEATQAGSWEWNLETGEWRVDARWAAMLGL
                     PPEACTGLGRASWRERVHPADLAEAELELERHIRGETAFYEHDLRLRHRDGNWIWVHD
                     RALAVRRDADGRALLLTGAQVDIDRRKENEERLRLAASVFSSSYEAILITDADNRIVD
                     VNPAFCRITGYSREESLGRDPGMLASGRQGREFYRAMWQALEEHDHWQGELWNRRKDG
                     GEFAEVLSISRVRDARGRVIHHLAMFSDISRLKKHEEELNRIAYFDPLTGAPNRRLLD
                     DRLRQAIAHSRRTGRPLAVCVIDLDGFKPVNDQLGHEAGDQVLVGIVDRLATILRASD
                     TVARVGGDEFVLLLEDIDGERVLERVLDAIRMPIALATRQVSVSASIGVTLFPEDDAD
                     PDTLLRHADQAMYRAKQRGRNCIQFFDASVEEQQRVRKERLERLELALRRHEFVLHFQ
                     PQVDMADGRPLGMEALLRWQHPERGLLLPGDFLPDLEGTELETRLGQWVID"
     gene            complement(39261..41288)
                     /locus_tag="P5537_03280"
     CDS             complement(39261..41288)
                     /locus_tag="P5537_03280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HRV77097.1"
                     /translation="MTEASRPESAPAEAELRFADLQLPAALLSALAEVGYETPSPIQA
                     ACIPQLLAGHDILGEAQTGTGKTAAFALPMLAKLDLADTRPQVLVLTPTRELAIQVAE
                     AFAKYAHHLKNFHVLPIYGGQSMVVQLRQLSRGAQVIVGTPGRVMDHLERESLKLDAL
                     KAIVLDEADEMLRMGFIDDVEWILEHTPAERQTALFSATMPNVIRDVARRHLRNPQEI
                     KIRAATSTVAKISQRYWLVRGVDKLDALTRILDAEESFDAAIVFVRTKIATEELADKL
                     AARGYAAAALNGDMNQGLRERVIEQLKNGALDIVIATDVAARGIDVPRVSHVINYDIP
                     YDTEAYVHRIGRTGRAGREGVAILFVAPRETRMLKMIERATRQPITPIALPSSEEVTN
                     LRVAQFKRQVAETIAGAELGFFMGVVNDLIEENELEIHEVAAALALLAQRERPLQVEQ
                     SGRGWDIATTTPSEGRAPRAEHFTTGAARERTPRPNRDEILARRRSFSEGALVRYRIE
                     VGRAHGASPKEIVGAIANEGGIEGKFIGQIHLFDEFSTVELPANLPEDLLATLKRTRV
                     RQMPLSIRELSAAEAASVPERRRPARPEGGDGFRSQDADRRPRDFGGPRPGQPGGGYG
                     GKPGGGFRGHDERRPHDERRPPSTDRKAGGHSAPVKRQGERGGKPFRRRED"
     gene            complement(41533..41742)
                     /locus_tag="P5537_03285"
     CDS             complement(41533..41742)
                     /locus_tag="P5537_03285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011765852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HRV77098.1"
                     /translation="MSTQTGTVKWFNDAKGFGFITPEGGGDDLFAHFSEIQSKGFKSL
                     AENQRVEFEVKTGPKGLQAANIRPL"
     gene            42025..42996
                     /gene="ylqF"
                     /locus_tag="P5537_03290"
     CDS             42025..42996
                     /gene="ylqF"
                     /locus_tag="P5537_03290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HRV77099.1"
                     /translation="MPIQWFPGHMASARKKAAEAMAMTDVVIEVVDARLPEASSNPMI
                     AELRRFRNRPCLKLLNKSDLADPEATRAWMDFYNRQPGVKAVAISAKSPAEVARVPAL
                     CRQLAPHRDDGTKPLRMMIMGIPNVGKSTLMNALLKRKVAKVGDEPAVTKHQQTLDLG
                     PGMTLTDTPGMMWPKIDHDADGYMLAASHAIGRNAVIDEEVAAFLGEILIARYPGRLV
                     ARYRLDAAAVAALDGPALVEGVGRRRGCLVKGGGLDLEKAAQILLQDYRDGALGRISL
                     ETPQTRAAMIAAAQAAAAQAVSAGEAAGQDAAADTAGEGDAGGDGGD"
     gene            43416..44321
                     /locus_tag="P5537_03295"
     CDS             43416..44321
                     /locus_tag="P5537_03295"
                     /EC_number="3.1.3.97"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097657 - 3',5'-nucleotide bisphosphate
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3',5'-nucleoside bisphosphate phosphatase"
                     /protein_id="HRV77100.1"
                     /translation="MSVPSASRLHALNVDLHCHSTVSDGWLEPEALVLRAISNGVELL
                     ALTDHDELGGIAAAQGVARAHGLAFVPGVEISVSFAGETVHIVGLGVDPECPALRAGL
                     AALRAGRDGRARRMGEELARVGIPDAFAGACRFARNPALVSRAHFARHLVASGVMPDV
                     KTVFDHYLVRGKPGFVEHRWAALEDAVGWIRAAGGIAVVAHPARYRLSSVALGELFDR
                     FVAAGGEAVEVVAGAHTEDDMRRFASLARQRGLLASRASDFHGVQESMVDVGRCNPLP
                     ADLEPVWSRLPATAAALAAAASSVR"
     gene            44349..44972
                     /locus_tag="P5537_03300"
     CDS             44349..44972
                     /locus_tag="P5537_03300"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HRV77101.1"
                     /translation="MAQYFSLHPEQPQARLIRQAAEILRGGGLVALPTDSAYALACQV
                     GDAALLDRIRRIRGVDERHHFTLMCRDLSEIGTYARVDNSQYRLLRAVTPGPYTFILE
                     GTKELPRRVLHPKRKTIGLRVPEHAVVSALLAEIDGPLLTSTLILPGDELPLTDPEEI
                     RDRLGKLVELVIEAGYCGPEATTVIDLTSGAPELVRAGRGPLEPFGL"
     gene            45000..45659
                     /locus_tag="P5537_03305"
     CDS             45000..45659
                     /locus_tag="P5537_03305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HRV77102.1"
                     /translation="MDSLISTLAIWALPVVLAITLHEAAHGYVARHFGDPTAHLAGRI
                     TLNPLRHIDPVGTILVPAGILALSSLAGAGGILFGWAKPVPVNFSRLRNPKADMLWVA
                     AAGPFVNFVMAIGWAVLFRVAATAEPGAYTLPMLKMADAGIQINAVLMALNLLPIPPL
                     DGGRIAVSLLPNRLAWQYARLEPYGFPILLVLLFTGVLGTLLWPLIAGFRYLLSLVFG
                     F"
     gene            45666..46868
                     /locus_tag="P5537_03310"
     CDS             45666..46868
                     /locus_tag="P5537_03310"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HRV77103.1"
                     /translation="MYAERVLSGMRPSGRLHLGHYHGVLKNWVKLQEEFPCLFFVADW
                     HALTTHYDTPEVIEANVWDMLVDWLAAGVDPAQSTLFIQSQVPEHAELHLLLSMMTPL
                     GWLERVPTWKEQQEKIEGRDLSTYGFLGYPLLQSADILIYRADKVPVGEDQVPHVEIT
                     REIARRFNHLYGREPGFEDKAKDAVRKLGARRARMYHELRTRFQQEGDDDALEQAKAL
                     LDETQNLSLGDRERLYGYLEGSGKMILVEPEALLTPAARMPGLDGQKMSKSYGNTINL
                     REDAESVTRKVRTMQTDPARMRRTDPGEPERCPVWQLHAIYSGEETLAWVQQGCRSAG
                     IGCLECKQPVLEAILREQEVLNERAQPYLDDPSLLRSIIADGCERARRLAQETMRDVR
                     EAMGLDYG"
     gene            46906..47736
                     /locus_tag="P5537_03315"
     CDS             46906..47736
                     /locus_tag="P5537_03315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004371061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ScpA family protein"
                     /protein_id="HRV77104.1"
                     /translation="MNLPLDLAPVDTGAPLDVLARIYGEPLLELPKDLYIPPDALQVF
                     LEAFEGPLDLLLYLIRKANLDILDVPMAPLTAQYLEYVEAMRATNLELAAEYLLMAAM
                     LLEIKSRMLLPRPPRENAEEEDPRAELVRRLLEYEQMKLAAARLEALPRVERDFEWVG
                     VFVAEKVVERLPEVSLHDLQLAWLRIMKKARLNQSHRVGREQLSVREHMTAILRRLGD
                     GAFVVFDTLFDVELGPPGLVVSFLAVLELVKERLVDVTQNEAFAPIYVKLADATRNDA
                     "
     gene            47714..48316
                     /gene="scpB"
                     /locus_tag="P5537_03320"
     CDS             47714..48316
                     /gene="scpB"
                     /locus_tag="P5537_03320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HRV77105.1"
                     /translation="MQPATTPETWLRIVEAALLAAPGPLPVSELRKLFDEDPGPDLVR
                     RLLDELRTQWFEAARGVELVQLASGWRFQTRPEYQVYLDRLKEEKPPRYSRAVMETLA
                     IIAYRQPVTRGDIEDIRGVAVSPNVLKTLESRGWVDIVGHRDTPGRPALFATTRRFLD
                     EMGLRSLTELPALTELEKIMDLVDVSQTEPAAAPAPEEEV"
     gene            48264..49424
                     /locus_tag="P5537_03325"
     CDS             48264..49424
                     /locus_tag="P5537_03325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HRV77106.1"
                     /translation="MSRKPNRPLRPPLKKKSDAIEILDRDPRESRGGRRGEGAPRDED
                     AQPSRKDAHLNVDPRGPRTPRPPRAGGAPAPRRPRIEGDPARHPEAHRSALGQPEAGE
                     RPARGRGQGGGRNAPTTLTEPERLQKVLAQAGVASRREIEEWVVAGRISVNGLPASLG
                     QKIGPGDRVKVNGKLVPLRFTQRSPRVLIYHKPEGEIVSRDDPEGRPTVFERLPILRK
                     GRWLAVGRLDFNTSGLLLFTNDGDLANKLMHPRYELEREYAVRILGELTEEQVKSLTE
                     GIQLEDGPAKFNLLRDEGGEGANHWYRVTISEGRNREVRRMFEAVGLTVSRLMRVRYG
                     SVELPARLKRGMWMEMPEAEACALAGLPPPQQSRQQDQRDKRPVKLHRTQPR"
     gene            49692..50126
                     /gene="rimP"
                     /locus_tag="P5537_03330"
     CDS             49692..50126
                     /gene="rimP"
                     /locus_tag="P5537_03330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HRV77107.1"
                     /translation="MRADVEGLIEQVVTGLGYELVDVEFSPKGRLLRVFLDIERGITV
                     DDCATVSNQLQRVFEVENVDYDRLEVSSPGLDRPLKKLADFERFAGEQAQVRLSLPIG
                     NQRNFVGVIERVQDGAVALRTEKGEVLLPFDDIEKARLVPQF"
     gene            50154..51629
                     /gene="nusA"
                     /locus_tag="P5537_03335"
     CDS             50154..51629
                     /gene="nusA"
                     /locus_tag="P5537_03335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011239105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HRV77108.1"
                     /translation="MSREILLLVDALAREKNVAKEIVFSALETALASATKKRIHDDAD
                     VVVSIDRDSGDYTSKRRWLVMLDEEVVNDEAEMGIIDARELRADVQIGDYIEEELEPI
                     DFGRIGAQAAKQVILQRIRDAEREQVLNDFLDRKEFLVSGSIKRMERGNAIIEVGRME
                     AVLPRDQQIPRENLRVGDRVKAFLLRIDRGARGPQLVLSRTAPEFLMKLFELEVPEIE
                     DGLLELKACARDPGLRAKIAVKSNDQRIDPIGTCVGLRGSRVTAVRNEIGGEQIDIIV
                     WSPDPAQFVVAALQPAEVVSIVVDEESHAMDVVVDENNLAIAIGRSGQNVKLASELTG
                     WTINLMSEQESAEKTAQEQQGLRALFMEKLDVDEEVADILIEEGFSSLEEVAYVPLSE
                     MLEIEAFDEDTVNELRNRARNVLLTEAIVTEEQLEKVSDDLLGLEGMEKSLAATLAQQ
                     GIRTRDDLADLAVDELVEMAGIDEERAKALISVARAHWFEE"
     gene            51643..>52639
                     /locus_tag="P5537_03340"
     CDS             51643..>52639
                     /locus_tag="P5537_03340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2 associated
                     domain-containing protein"
                     /protein_id="HRV77109.1"
                     /translation="MEQMSVTQFAGELKMPAAVLLEQLKRAGVEKSGPTDLLTEQDKA
                     RLLEYLRRSHGDTQPKGKITLTRKQTTEIRATDSTGRARTVQVEVRKKRTFVKRDELA
                     EQAGVEAAAVEPAELAEAVMEAPVAVEAVARAVEAVAPVAEAAAVEVAPAVEAAAPAA
                     IESSEPVAVVSVAEVEAPTPAPVAEVEAPAPVAAPAPAAAPAAAASTAARPAQQGGRQ
                     GRGERQSRQEPAPQPQVTTVLSKPLPLSEILSEEEIAARKRDEDRQRALKERQAADLR
                     ARQEREAAAKAAAEARKAEEEARLRAEQQKKEEPAKAAAKPTTGTLHRPAKTEDKP"
BASE COUNT         7842 a        17736 c        18648 g         8213 t
ORIGIN      
        1 gcatgtgctt agttcctgca agtcgtccaa ctcgaatggg aggatgggtc atttgcggtt
       61 tcggatcaag gcggtttgga tgtcgacgat gtcgcccacg gtgatgtgcc gaggaggggc
      121 gggaggcaga cctttcaggg tcgagggtca ggtcttgcat ttgctcatcg cctgcccctg
      181 cggcgtcgct tgaaacgcca cgaccgccgg cggtgtcgcg cggctctcgt cgcttgctgt
      241 ggcggcttcg cctgctcgcc tacctgaaac gacacgatcg cgctatggac gaacgagggc
      301 atgcaggcat aacctatgcg cacacacgaa tgcgcatgga gggatcgatg ccagccacac
      361 ggagtaccca acgcgcgcgc acccattcat ctggcaagcg cgcgacaaac ctgagcctga
      421 gcagcgatgt tctggaggcg gccaggcaac tcgacatcaa catttctcag gtctgcgacg
      481 cctacttgcg tgagcttgtg cgccgcgagc aggcgcgcaa gtggcgcgag gatcatgccg
      541 atttcatcgc tgcctacaat gcgaccgtcg aagcagaagg cttgccgctc gaagcgtgga
      601 gaaatttttg atggcacgtt tcgacgtcta tgccaatacg ggaggccacg ccgacacaac
      661 gccctacctg ctggatgtgc agagcgatct gctcgacgca ttagacagcc gtgtggtgat
      721 tccattgcgc agtctcgcgc acttcccgaa gatcaggctg cctgcccgtc tgacgccggt
      781 gttgaccgtt gagggcacgg attgccttct ggaaacacca aagatgggcg ctgtaccgct
      841 gcgagcgctg aagtcgcccg tgacttcgct tgcgcacgcg caggagcaga tcaccgctgc
      901 attggatttt ctgttccagg gctactgacc tcgagggagc gaggaaatcg gggacagacc
      961 agaaatcggg gacagaccac tttttctcgt cgcctgaaac gccgcgaccg ccggcggtgt
     1021 cgcgcggcgg tcgtatcggg tgcggctggc ggcttatcgg ccatcgctac cccgagcacg
     1081 ccacccctgc ctcgaaatag acgtcggcga tcggcatctg cagctccacg ctggcgaatt
     1141 cgaccgcgtc gccgggctcg aaggtgatga tgtcccaagc gatgtcgccg cggcggcggt
     1201 agagctcgag cttgcattcg tcctggctga ccagggcata ctccttgagg ctggggagcg
     1261 tgcggtaggc gcgaagcttt tcgcggcggt cgatgccttc ggtggagggc gagaggactt
     1321 cgatgatcag gggcgggctg tcgacgatct gcatctgggc gtcgagctcg agcagccggg
     1381 actcgcaggt gaccatcacg tcggggtaga agtagctgcg ctccttcttc aggtacagct
     1441 tcacgccttc catgagggcg cggcagggtg tgccgcgcag gtgggtgcga agggcggtgt
     1501 agaggttgcc tgcgatgatg ttgtgacgga tgctcgcccc ggtcatggcg aagatttcgc
     1561 cggcgacata ttcgtggcga acgggcgagc tggcctccag ggtgaggtac tcggattcgt
     1621 ccagcagtcg gtagggttgg gattgcatcg tgccgtcctc gtctcgtacg ccttgtgccg
     1681 ctgattatag agccggcctt cgccccggcg accgcgcagt cgatgtcaca gcggcacgta
     1741 gggaaaatcg gggacagatc acgtgttctc ctcgcctgaa acgccacgac cgccggcggt
     1801 gtggcgcggc ggtcgtggtg gggtggtgcc tgacaggtgg cagtgatagt ccggcggtgg
     1861 gccgagggtg tcggtgagct tggtggcgtc gaggatggtc tcggtccatt ctgaggcgct
     1921 gagggccttg gatgtgatct gtgttgctcg ccgtctgagg acggcttggg actgcgctct
     1981 ggacgcgagc atctcccggc ggcgtcgcca aggccaggtc agcgcttcaa gtcgcggtag
     2041 aaattctcgt ggggaccgac ggcctccaga tataccaacc gaacgccgcc atcgcgggtg
     2101 tagcccagca ggtacaactg gccgaggcag cggaacttgt agacccacaa ttccgcgagg
     2161 tcgcctttct tcttttcgcc gctgtcaggg ttacaggcta ccgcttcgac ggcggcatcc
     2221 acctcggcca acatgttgtc gtgcagtttc ttgtagacac gagcaaagcg tcgcgtttgc
     2281 cgaacgtccc agctcatgcc ttggctgtcg agcgcggtac gaagacggtg ctgtcctcac
     2341 gcggttcggc catgctcatg aggctttcgg caatgaacga ggccggcaga tccgggttgt
     2401 cgagcgcggc ccgacccact ttggcccaga actcgacctg gccttgcacg gtacggaact
     2461 cggccttggc tgcagcgcgt gcggcgctga ccaggctctc atcgatacgc acggatacgg
     2521 tgctcattgc gatctccact ggaattgatt gactacaatt gtaggcgggc gcggttttgt
     2581 ggtcaaagga ccagaagagt tgggggcgag ggcattgtgc gcgcgcatac gcgctcgggg
     2641 cctcgatgat ggcagccggg tcgtggatgg ggcttgagcg acccttgcat gccccagggc
     2701 gcgcagggct ctcatttact catcgcttgc cctggtggct tcgcctacct gaaacgacac
     2761 gacagagcga tagactcggg agggcatgcg ggcataacct atgcgcacac aaacatgcgc
     2821 atggagatgg cgatgccagc cacacgaagc acccaacgca tgcgcaccgg ttcatccggc
     2881 aagcgcgcca taaacctgag cctgagcagc gacgttctgg atgcggccaa gcaactcgac
     2941 atcaacatct cccaggtctg cgatacctac ctgcgcgagc ttgtccgtcg cgagcaggcg
     3001 cgcaagtggc gcgaggatca tgccgagttc atcgctgcct acaatgcgac cgtcgaggca
     3061 gaaggcttgc cgctcgaagc atggagaagt ttctgatggc gcgtttcgac gtctacgcca
     3121 atacgggcag ccacgctgac acgacgccct acctgctgga tgtgcagagc gatctgctcg
     3181 acggcctcga cagccgggtg gtgattccat tgcgcagtct cgaacacttc ccgaaggtca
     3241 ggttgcctgc ccgtctgaca ccggtattga ccatcgaggg aaaggactgc cttctggaaa
     3301 caccaaagat gggtgctgtg ccgctgcgag tgctgaggtc gcccgtgact tcgctcgctc
     3361 gagcgcagga gcagatcacc gctgcattgg attttctgtt ccagggctac tgaccaggtg
     3421 attgggctac gccgagcacg ccaccccgga ttcgaagtac acatccgcga tcggcagcgc
     3481 cagctccacg ctggccagtt cgaccgtatc accgggctcg aaggtgatga tgtcccagcc
     3541 gatgtcgccg cggcggcggt gtagttcgac gcggcattcg tcctggctga ccatggcgta
     3601 ttccttcagg ccgggcaggg tgcggtaggc gcgcagcttc tcgcggcggt cgatgccttc
     3661 ggtggagggg gagaggacct cgacgatcag cacggggctg tcgacgacct gcacctgcgc
     3721 gtcgagctcg agcaggcgcg gctcgcaggt caccatcacg tcggggtaga agtagctgcg
     3781 ctccttcttc aggtagagct tgaccccttc catgagcgcg cggcagggcg tgccgcgcag
     3841 gtnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnctcaatcg gcgttgcgga
     3961 acaccttctg ccacgggacc gagacctcga ggctctccag caccagggcc tgctcgggcg
     4021 cgatgtcctg cagctcccag cgctcgtcct ggctgcggcg gtagtgctcg atgcggcgca
     4081 ggtcggggtc gatgaggacg aagtcgcgca gcgaggggat gcggcgatag gcggcgaact
     4141 tttcgccgcg gtcgtaggcg gcggtggcgg gcgagagcac ctcgacgatc agcgtgggcg
     4201 cgcgcatgaa ctggtcggcg cggtggtcgg cggggtcgca ggtgacgagg acgtcggggt
     4261 agaagtaggc ctcgtccgca gcggcctgga ccttcatgtc ggccatgtag gtgcggcagg
     4321 ggctgccttc gagggcctcg tcgagggctg cggcgacatt gagcgagatc gtcacgtgcc
     4381 ggcggctggc gccgcccatg gcgaaggtct cgccgtggta gtactcgtgc ttgtcgggct
     4441 ggccggcttc ccaccgcagg tagtcttcgg cggtgaaggg ggcggtgggc tggggcaggg
     4501 ccatgatgtg cgcgtccggg cggtgaaatc tcgaagggat tatagtccgg cacatgaacg
     4561 ccaagccccg ccacgtcgaa cgtgcgctcc acgagcgggt cgagatcgtg ccctacgatc
     4621 cggcctggcc ggggctgttc gccgaggagg tggcgcggct gcgcgcggcc ctgccggcgg
     4681 atctgatcgg gcgcatcgag cacttcggca gcaccgcggt gccgggcctg gcggccaagc
     4741 cgatcatcga catgctggtc gaggtgcgca cgatggagga cgtggcgcag cgcatcgcgc
     4801 cgctgctgca ggcgcagggc tacgagttct tctggcgggc gcccgagcac ggcctgccgg
     4861 gcatgaacta cgcgtggttc atccgccgcg acgcggcggg gcggcgcacc caccacatcc
     4921 attttctcga gaccggctcg tcggaatggg agcgcctgct gttccgcgac tacctgcgcg
     4981 cgcaccccga ggccgcgcgc gcctacggcg agctcaagca gcgcatcgcc gccgagcatc
     5041 ccgacgaccg cgtcgcctac gcgaaggcga agacgcgctt cgtgcgcgcg gcgatgcagg
     5101 ctgcgcgcgc ggaggtcggc ggtccgcgtc gggtttgatc gccgcttcga tcatttcgac
     5161 caactcgtca ggtcgtggcc gcaacagggc ggtcgagttc gcaataaaaa agaggctcct
     5221 tttcatggga gcctccattg tacgttctgg attgtctgcg gtagatggcc tggaaaagct
     5281 caggtgtccg tgcgcgaatt aaattactca acccgaagga tatcgcggag ttcttgaatc
     5341 aatcgcttac tgtccgtccc ggtagcctcg cttgaaatcc tcttcgagcc ctttgtcctt
     5401 cgcgtctcga taggcttctt tttcggctgc ggtcatcctg ccggatttgt tctgccccga
     5461 cttgcgggct tccgcggctt ttttgcccgc ctctctggct ttgttccggt catttccgtg
     5521 accggagccc cagcgctgct cgctcgactg cgccatggag tcggtcggag tcattagcgc
     5581 tccagtgccg aaaacaaggg ccattgcgag gatggtgacg gctttcattt tcatgtttgc
     5641 atctccttgc gtcggaacga cgtcgaatga attgttttct ggataagggc ggccgcattg
     5701 cctgattccg gggtacatct catgagcttc gattcaagtc tagagtcttt gccggttctg
     5761 cttcaatcac ggattggttg cgatcgtgaa ttaattggct atcgagtctc gcgttcgggt
     5821 aatgcgaccc agattgggga tttaggatag atgtcgtgaa tctcagccgc ccgggccggg
     5881 cttgatcgcg gcctccatcc gcgtggccat ctcgtcggcc ccggcgggat gtcctgctcc
     5941 atgccgctcc cgtggtgatc gccctctcaa cagggctgat gatcggtggt acaactgccc
     6001 gataccgatg ccgaaattgc accgcatgaa tgcagcctat cgagaccttg ccagcgtccc
     6061 cgcgccagcc gtgagcatcg gacgccctgc tgaagacctg cccgggcgga tggcagagcc
     6121 tggggagtcc gggcgcgggc gcgtgcccgc gtgggctcgc tgcgcctgcc gcggagggcg
     6181 actgcggtga cggcgcctat ccagggtcgc cgcccgttcg cggtgtggct gatcgtgctg
     6241 ttgctgctcg cctacggcct gctgggtccg ctcctgctgg tggccggcag tggctccatc
     6301 gccaccatca cggaggtccg tcgcaccggc ggggccgagc cgcagtggtt ccaccgctac
     6361 tggtgggtcg tggcctacga gttcacggcc gcggacggca cgctgcatgg cgggcacacg
     6421 cggaccctgg cgtacgacac cggcccgcgg ggctacgcga aggtcgagcc ggtgctgtac
     6481 ctggcggcgg cgccgtggct caacgtgctg cgcaaggagg ccggcgtcca tgccgggacg
     6541 gtcgccgtgc tgggcgccgc gctgctgatc ctgtggctga cccgtgcacg acaaccgcaa
     6601 cgtggcgccg ccgtgccggc tgcgggcaag cggacggctg gcgggcggcg cagccgagcg
     6661 agcgcgactt cgggcgcggc caccgcgatg acggtcgagc agtcgcggcg ctggctgctc
     6721 ggctaccgcc gccacagccg gctgtacgcc tggctgttct tcgccgcggt gatcccggtg
     6781 gtggtgctgg tgatctggct ggaggtcggc gagctcgacg aggaggtgct gggctcggtc
     6841 gccttcttca tcgtggtgtt cctcgcgctc gccctgggtt cgcgccggca gacgagcgcg
     6901 gcctggcgag ccgtggtcgt ggataagcag cgcacggagc ggggcgccgg cggcacgctg
     6961 gtgctgcaac tcgagcgcgg cgagcgccgt acgctgcggg tgtcgccgcc cctgttcgat
     7021 tacttcgcgc ccggtgacgc ggtgttcaag ctggacggct tcgagtggcc ggagaagtgg
     7081 tctccggacg aggggcgcag ggtgtgcatc gcctgcggtg gcgtggtcga gctcgcagag
     7141 cccatgagcg cctgcccgcg ctgcggcgca ccactgcccg cgcacgaggc gatgcaggcg
     7201 ctggcgccgc gcgcctgacg ccggacggcg cagggctcag cgcggcgcga agccaccccc
     7261 caccggcacg ccacccaccg gccgccctgc cgctgcgggt tcgggcgtgg gctcgaccaa
     7321 agtgcgcacg cgatagccgt tgcggaactc cgcctggtag cgcgtgctgc ctgccgcgtt
     7381 cgtctcggtg cgcgtgccgt gccacatgat gaagagctgg cgcttgctca gcagcgcatg
     7441 gcagcgcttg ggcatggccg ccgcgatcgc ggcctgcgat tcgtggtcgg gcatcgagct
     7501 gcggaaggtc tgcgtgagca cgcgctcgat ctcgtgttcc tgcagtgcct tgccggcgcg
     7561 ctcccgggcg agccgcacga cctcgtcgcg cggcatgagc aggaaggcga accgggtgcg
     7621 ggagcggtcg gcgtgggtga cctggacgtc gaagaccgtg ccttcgcagg acgtatcggc
     7681 tgccggcggc ggtgtatcgg cggccgcgag cacgcggagc gtggtgtgcg cgctcacgct
     7741 gcggccgagg tggtcgcgca cggtgaaggc gagggggtgc gtgccggggg tgtcgggtgc
     7801 gcggacgttg gcgatcgcgc cgcccggggc gggcatcgag tcggcgccga cgacggtgaa
     7861 gtcgggcacg ccgccgacga ccagcaggct gaagctcacc cagtcgcccg cgcgcgcggc
     7921 ctcggggccg ctgagcacca cccgttgcag gggcgcggcc tcggcgatca ggcgctcgac
     7981 gagcccgatc acgcgccggg tgtgttcgag ggcggggcgc aggatcggat acaccgcatg
     8041 gccgtcctcg aggatcttgc tcgcgtcgag caggtgctcg cgcgcctggc gcagctgccg
     8101 acccttgcgc gccaggccgt agccggcgtc gtaatgcacc cgcgcctcgg cgatgatgcg
     8161 gttggcctgc agctggtcgg ccgcggcgtc gaggtggcgg tcgaattcga gcagcctggc
     8221 gaggatccgg tcgtcggcct cgtcgcgctt ctggtagaaa tggcgcagct tggtgaggta
     8281 gctgcgcgcc tcggcgagct tgccggcctt gatcagctcg tcggtgcgca gcaggccctg
     8341 cagcacgttc gcgcgggcgg cgatcgcgac ctgctgctcg gccagcgcgg tgttctcgag
     8401 gtcgtagtgc agcaggatca tctcgttcaa catctcgccg accgcggcgg cggacaggct
     8461 gaccaccagc ccgtgcagga agagcccgcc gccgagcacg cgcacgccca cgttggcggc
     8521 ggtctccagc ccgtagctcg cgatcgtgcc gctggccgcg gccgcccttt cctctgccgt
     8581 ctcgagcttg cggatccggt tgatgtccag gagcgcgaag gccgtgtcca tgccgccgcg
     8641 cgtgaacatg tcgaatccgc tgacgccgtg taccgcgaac tggttgcgca gcagccggtg
     8701 gccggcgagc gcgcgctcgg agggcagctt ggcgagcgca tcggccagct tgcggttcaa
     8761 ctccttcgag aggctgccgt tcttcgcgag ctgggccttg gcttgctgca gcaggtcgag
     8821 cgcctcgcgc ccggccaggt cgacccccgc gtcggagtgc gcgacgatgc ggcgcagcac
     8881 ggcgtcgccc tggccggcga gcccgtcggc gtagtcctgc accaggttgg cggcgtgggc
     8941 gcgcaggccc ttgcgttcga tcagggcatg cagctcgtcg cggcttccga tcctgcgcag
     9001 gtcggcccag aactggcggg cggcatcggc gttgtgctgc aggacctctc cggccgcgcg
     9061 cagctcgtcg gtgacgagct tgcggacggc ctcgtcctcg ctgaactggc gaagggtgag
     9121 gtttatccct tcgacggcgg tgttgtgcca gctcttgatc gcctcgttgc cggctgcgtc
     9181 gtcggcccat tgcaggtcgt cgggcgcggg gcgggcgagg gcgagggggg agcaagcgag
     9241 gggcgagaac acgagggcgg cggcgaggcc cgcgagcgtc caggccctgg cgcgcaggcc
     9301 gcgcgccgga agggcgaggc gcggacggcg cgattgcgca gggcggtttg ggtgggccat
     9361 gcgcgtcatc ttccccaggt ggccagcggc gaacccaggc gcgcggcccg ctcgcgtagc
     9421 gaacgcgcgc gcgccggatc gggctccacc cacaggccgg agtcgagctc gtcggcgagc
     9481 atcgccatcg cgtccgcatc gcccgccgct gcggcgcgcc gcagccaggc gatgccggcc
     9541 tcggggtcgg cctgcgcgcc gaggccccgg agcgcgagca ggccgagcag ggcctgcgcg
     9601 cgcggggcgc cggcggaggc gtcctgctcg aggcgtgcgc gcgggtcggt cggatcggtg
     9661 tcgatcgaga cgatgccggc gatgccttcg gtccggaggg gggggcggct gctcggggtc
     9721 ggcgccgcgg gcgcgggggt tcccggggcg ctccggcccg cgccctcgag gcgggcctgg
     9781 agggcgcgat aacgcgtcga ggcctcgcgg taggcggcga gcgcagccgc ccggtcgccc
     9841 ttggctcctg gggtggtgac gaggcgggtg tagtgctcga aggcggcctg ataggcggcg
     9901 cgcgcctcgg cgagttgcgc gggatcgacc gcgtccgcgg cctgcgtcgc cgacgcaatc
     9961 gacacgcacg cgagcagtgc ggcgatcagc ccccgccgcc gcgcgcctgc aggcaggggc
    10021 ggcctcatgt gtcgcggcct ccggtgtgtc cgctcaccgc cgcccgcggg cagcgcgcca
    10081 ggatgaagtc gcgcacgaag gcgaagtcct ccggcgcggc gtagacctgg ttgcgggtga
    10141 gcctttcggc gaggtggatg acgccgcggc gctcgtcgat gcggaccttc cggaccttgg
    10201 cgaaggcggt gtggagactc tggcgcgagg cggcgagcag gcccgctccc gcggcctgcg
    10261 ggctgccggc ggcgatgccg gcgagtacgg tgacgaaggc gacggcctgg ttacgctcga
    10321 actgcttgcg gagttgtgtg tgccggacgc cgcgttcgtc catctcgaac accacgcagt
    10381 agcgtccgcc ctgcaggatc gcggtgagcg ggtaggcgat cagcagcagg acggcgacga
    10441 tgccgacgac gatgccgccc acctgcgcga cgctgccgag ggcggcgccg atcccgtccc
    10501 cctcaacgag ggcgaggacg ccgaccagca gcgcgggcac cgaggccgcc agcagcagga
    10561 ccttcgccgt ggtgatgagc acggtcgggt tcttccacag gctgatctca tgtacccagc
    10621 gcagtacgcc gtcccggccc ggcgtgatgc cgggggcggg acgcgctgca ggaaccggat
    10681 cggaatgcat gccgatgctc gtgagtcggg cgccgcagcc cggggccggg ctgcgggcga
    10741 gcccggctta catgccctgg tagatcggcc cttcgccgcc ctgcggcacg acccagttga
    10801 tgttctgggt cgggtccttg atgtcgcagg tcttgcagtg gatgcagttc tgcgcgttga
    10861 tctgcaggcg cgggccggcc tcttcgtgga cgatctcgta cacgccggcc gggcagtagc
    10921 gctgttcggg ggcgtcgtag cgggcgaggt tgaccgagat cgccaccgac gggtccttca
    10981 gctgcaggtg gcagggctgc tcttcctcgt ggttggtgtt cgacaggaag accgaggaca
    11041 ggcggtcgaa ggtgagcacg ccgtcgggct tcgggtagtc gatcttcggg cactcggagg
    11101 ccggcttgag cttgtcgtgg tcggacgagt tgtggagcgt ccacggcgcc ttgccgcgga
    11161 acagcatctg gtccatgccg aacaggaagg agcccatcca cagtcccttc ttcatcagcg
    11221 gcttgaagtt gcggtacttg tgcaactcgg tgtacagcca ggactcgcgg aaggcggccg
    11281 ggtaggcggt gagcgcgtcg cgctggcggt tggcggcgag cgcgtcgaag gcggcctcgg
    11341 cggcgagcat gcccgacttg atcgcggcgt ggacaccctt gatgcgtgcg gcgttgagga
    11401 agccggcgtc gtcgccgatg aggccgccgc ccgggaagat cagccgcggc aggctctgca
    11461 ggttgccggt ggcgatggcg cgcgcgccgt aggccaggcg cttgccgccc tcgatgtgct
    11521 tgcgcacctc gccgtgggtc ttccagcgct gcatctcgtc gaagggcgac aggtgcgggt
    11581 tctcgtagtt gaggccgacc acgaagccga gcgcgaccag gttgtcctcg aggtggtaga
    11641 tgaagccgcc gccgtaggtg cggttgtcca tcggccagcc ggcggtgtgc acgaccaggc
    11701 ccggacggtg catctcgggc ttgacctccc acagctcctt gatgccgatg ccgtaggtct
    11761 gcgggtcgac gccctcgcgc aggttgaacc tggcctcgag ctgcttgccg aggtggccgc
    11821 gacagccttc ggcgaacagg gtgtacttgg cgtgcagctc catgcccggc tggtggtgcg
    11881 ggccgggggt gccgtcgcgg ttgaggccca tgtcgccggt ggcgacgccc ttcaccgcgc
    11941 cggattcgtc gtagaggatc tcggcggcgg cgaagccggg atagacctcg atgccggcgg
    12001 cctcggcctg ctcgcccagc cacttgacga ggttgcccag gcgcacgatg tagttgccgt
    12061 ggttctcgaa gcagtcgggg gtcagcgcgg gcgggacgcg gcgcacgccg gtctcggaga
    12121 ggaacagcac ctggtcctcg gtgaccgcgg tggtgagcgg ggcgcccttt tccttccagt
    12181 cggggatcag ctcgttcagc gagcgcggat cgatgactgc gcccgacagg atgtgggcgc
    12241 cgatctccgc gcccttctcg atcaggcaca ccgagagttc gctgcccttc gcctcggcga
    12301 gctgcttcat gcggatcgcc gcggccaggc ccgccgggcc gccaccgacg atcagcacgt
    12361 cgaattccat cgattcgcgt tccataccgt tctcctcgta tcttcttgcc ttgggtcgcg
    12421 ccgcgagacg cgcatgcgtg cagtttaaac cttcgtgccg atcgccgccg ccggagggct
    12481 cgcgcaggcg cagcgtgcga ccgcgggggc gaacaaacat acgggtgcgt atgttacatt
    12541 agcccgcccc atatacaaga ggagatcgtc ggatgagtcc gaacgcgaag ctgatctaca
    12601 ccacccgcat gccggtgcgc tggggggaca tggacgccta cgggcatgtg aacaacaccg
    12661 tctacttccg ctacttcgag cagacccggg tcgagtggct cgagctgatg ggctcgcgcg
    12721 tgagcgtcga ggagccggtg gggccggtga tcatcaatgc cagctgcacc ttcctcgcgc
    12781 cggtgaatta tcctgcgacg gtcgtcatca agatgtatgc cggcgagccg gggcgcagca
    12841 gcgtgatgac ctggtacgag ctcttcgtcg aaggcgacga gcgcgtgtac gccgaaggcg
    12901 cggccaagac ggtgtggatg gacatgggca ccgggaagtc ggcgccgatt cccgatgtcg
    12961 tgcgtgcgct gttcgcgccg cccgccgcct gaacccgcac tggccggcga gcgaccggcc
    13021 agcgagcttg accaccccga tcaacgacac aagaggatgg agaggagacc cgatgtatcc
    13081 gactgagcag aaacccctgt ggaccccgtc ccccgagcgc atcgccgccg cccgcgtgac
    13141 cgccttccgg ctcgcggccg cgcagcgctg gggcgtggcg ctgcccgact acgaggcgct
    13201 gcacgcctgg tcggtggcgc agcccgagca gttctggacg agcgtgtggg aaggcgacgg
    13261 cgtcggcggc ggcgtcatcg gcacgcgcgg cgagcgcgtg ctggtcgatg gccacaggat
    13321 gccgggcgcg aagtggttcc ccgacgcccg cctgaacttc gcgcagaacc tgctgcgctc
    13381 gcgcgacgcg cacgacgcga tcgtgttctg gggcgaggag cgggtgaaga accgcctcag
    13441 ccacggcgag ctctaccgcg cggtggcgca cttcgctgcg gcgctcaagg agcagggcgt
    13501 ggtcgccggc gaccgcgtcg cggcctacat gcccaacctg cccgagaccg tgatcgcgat
    13561 gctcgccgcg gcgagcatcg gcgccatctt cacctcggcc tcgcccgact tcggcgtgca
    13621 gggcgtgctc gaccgcttcg gccagaccga gcccaaggtg ctggtggcct gcgacggcta
    13681 ctactacggc ggcaagacgg tggacgtgct cggcaagctc ggcgagatcg tgtcccagct
    13741 gccctcggtc aagcgcgtcg tggtcgtgcc ctacgtgcat gccgagcatg acctctcgca
    13801 tgtgccgcat gcgcgcatgt acgcggattt catcgccccc ttccacttcg tcgacgacat
    13861 cgagttcgcg cagctgccct tcgaccaccc gctgtacatc atgtactcct cgggcaccac
    13921 cggcgtcccg aagtgcatcg tgcactgcgc cggcggcgcg ctgctgcagc acctgaagga
    13981 gcacaagctg cacggcgacg tgaagccggg cgaccgcgtg ttctacttca ccacctgcgg
    14041 ctggatgatg tggaactggc tggtctccgc gctcgccgcc gaggccacgc tgctgctcta
    14101 cgacggctcg cccttcgccg gcgacaacca gatcctgttc gactatgccg acgccgagca
    14161 catgacgcac ttcggcacct cggccaagtt cctcgacgcc gccgccaagt tcgggctcaa
    14221 gccgcgcgag acccacaggc tcgagacggt gcgcgccatg atgagcaccg gcagcccgct
    14281 ggtgcccgag ggcttcgact acgtctatcg cgacatcaag gccgacctgc agctgtcctc
    14341 gatctcgggc ggcaccgaca tcatctcctg cttcgtgctc ggctccccgg tgctgccggt
    14401 gtggcgcggc gagatccagt gccgcggcct cggcatggcg gtggacgtgt gggacgacga
    14461 cggccgcccg gtgcgcggcg agaagggcga gctggtgtgc agcaagccct tcccggtgat
    14521 gccgatcggc ttctggaacg acgccgacgg cagcaagtac cacgccgcct acttcgatcg
    14581 cttcgacaac gtctggtgcc acggcgactt ctgcgagatc accgcgcacg gtgggctggt
    14641 catctacggc aggtcggacg ccaccctcaa cccgggcggg gtgcgcatcg gcaccgccga
    14701 gatctaccgc caggtcgaga agctgcacga ggtcgtcgag tcgctggtga tcggccagga
    14761 ctggccgccg cagaacccca acgacgtgcg cgtggtgctg ttcgtgaagc tgcgcgaagg
    14821 ggtgacgctg gacgacgagc tcacgaaacg catccgccag accatccgcg acaacaccac
    14881 gccgcgccac gtgccggcca aggtgctgca ggtggcggac atcccgcgca ccaagagcgg
    14941 caagatcgtc gaactggcgg tgcggaacgt ggtgcacggg cgcgcggtga agaaccagga
    15001 ggcgctcgcc aaccccgagg cgctggcgca cttccgcgac cgtgccgagc tgcagggctg
    15061 aggaggaccg aagacatgct gatgaacccg aagaagtcgg tgctgctggt gatcgacgtg
    15121 caggcgaagc tcgccccctt catccacgac aacgccgccg tggtcgacgc ctgcgtgtgg
    15181 ctcgcccgcg tcgccgatcg cattggcgtg ccggtggtgg tgaccgagca cttccccgag
    15241 aagatcggcg gtaccgtcga ggccgtgcgc gcggcgaccg ccggcgcgca ctacgtgggc
    15301 aagcagtatt tctccgccca ggccgatggc tgcctggagc acaccgcggt ggcgggctgc
    15361 gagcaggtga tcgtgtgcgg caccgaggcc cacgtctgcg tgcagcagac cgcgctcgac
    15421 ctgcgccgtg ccggcaagca ggtcttcatc gtcgccgagg cctcgggctc gcgcgatccg
    15481 gccaaccgcg acctcgcctt cgcgcgcatg cgcggccacg gcatcgagat cgtgtcgcgc
    15541 gagatggtcg ccttcgagtg gctgcagcgc ggtggcaccg agctcttccg cgaggtcaat
    15601 cgcgacttca tccgctgagg acggccggcc tcgccggccc cctgccatcg attcgtccgg
    15661 cccctggcga gcgcgtctcc cgcactaggg aaaacgtgcg tagccatgcc ggacgcgttg
    15721 tcctagcctg atcgcttcgt tccacggcga cgcgatccgg gctctctcga cgctgtcctc
    15781 acgagcctgc agaccgtccc gccgtatcca aaaacgcaag cgggaggttg gagatggaga
    15841 caagggaaac aggcaggctg gccacgcagg tcgacgcggt gatcgagcag atccgcgccc
    15901 ggctgcccgc ggagcaggcc gaaggggtgt gcgcgttcgc gagccgcttc ttcgcccagg
    15961 tggcgcccga ggacctcgag gacctcccgg tcgccgatct ctacggcgcc gtgctcagcc
    16021 agtggcattt cgtcgcccgc cgcaaggccg gcagcaaggt gcgcgcgttc aacccgcggc
    16081 tcgacgagca tggctgggaa tgtccgcaca ccgtggtgga gatcgccggg gaggacatgc
    16141 ccttcctcgt cgactcgatc accatggagg tggcccgcca ggggctcacg ctgcacctga
    16201 tcatccatcc ggtgatgaac gtcgcccgcg acgccgaggg cggcttcgtg cgcgtggccg
    16261 agcgcgccga gcagggcgag ggcatcggct tcgagtcgat catgcacctg gaggtcgacc
    16321 gccgtaccga ccccggcgac ctcgctgcat tgcagcaagg catcgagcgc gtgctcgccg
    16381 acgtgcgcgc cgcggtcggc gactggaatg cgatgcgcga gcgcctggcc ggcatcacct
    16441 ccgggctcga cgagctgccg ggcggcatcg atgccgatga ggcgcaggag gtgcgcgcct
    16501 tcctcgactg gcttgccgcc gacaacttcg tgctgctggg ctgccgcgac tatgccctgg
    16561 tcgagagcgg cgagggcaac gagctgcgca tcgtcgccgg ctccgggctg ggcctgctgc
    16621 gcggcgacgg cgaggagggg cagtcgcgct ccttcgccgc gctgccgcca cagctgcgcg
    16681 cgcaggccca cctgccgcac ctgctcacgg tcaccaagtc gaattcgcgc tcgacggtgc
    16741 atcgacccgg ctacctcgac ttcgtcggcg tcaagacctt cggcgccgat ggccgggtga
    16801 atggcgagcg cagggtgatc ggcctgctcg cgtccaccgc ctacagcacc agcccgcgcc
    16861 agatcccgct gctgcgacgc aaggtcgagg cggtcttcga gcgcgccggc ctgctgcctg
    16921 gcggccacgc cgccaaggcg ctgcagaccc tgctcgagcg ctatccgcgc gacgagctgt
    16981 tccagatcga caccgacgaa ctccacgccc acgccatggg catcctgcgc ctcggcgagc
    17041 gcctgcgcac gcgcctcttc gtgcgcgtcg atcccttcga gcgtttcgtc tcctgcctga
    17101 tctacgtgcc ccgggagcac tacaacaccg accagcgcga gcgcatgcag gcggtgctga
    17161 tcgacgcctt caagggcagc gccgccgagt tcgacgtgca gttctccgat tcggcgctcg
    17221 cgcgcatcct gatcacggtg cgcacccccg agggccggat cccggccttc gacgtgcgcg
    17281 agatcgagca gcgcctgatc cgcgcggcgc ggcgctggga ggacgagctg cagcaggcgc
    17341 tcgtcgagca gtgcggcgag gagcgtggcc tcgcgctgat gcggcgctac ggcgagggct
    17401 tcccggcggg ttaccgcgag gactactccg cgcgcatggc ggtgttcgac atcgagcaga
    17461 tggaggcgct cgccgacgat gcggcgctcg ggctcaacct ctacgtgccg ctcgaggtgc
    17521 gcgagggccg gctcgccctg cgcctctatc atctgggcag cccggtgccg ctgtcgcaga
    17581 gcctgccgat gctcgagaag atgggcgtga aggtgatgga cgagcgcccc tccgagatcg
    17641 agcgccagga cggcagcacg gtgtggctgc acgacttcgg cctgcagttc gccggcgccg
    17701 agaacctgaa catccacgag gtccgtccgc tcttccagga ggccttcctc gccgcctggc
    17761 gcggtgccgc cgagaacgac gacttcaacc gcctggtgct gctcgccggg ctgtcgtggc
    17821 gcgaggtggc ggtgctacgc gcctacgccc gctacatgcg ccaggcggcg ttcaccttca
    17881 gtctcgccta catggagcag acgctggcgg cctatcccca gctcgcgcgt gcgctgctgc
    17941 agctcttccg cgcgcgcttc gacccggcgc tcgcgggcga tcgcgaggcc gcgtgcgcgg
    18001 cgcaggtggc ggcgatcgag gccgcgctcg accaggtcgc caatctcgac gaggaccgca
    18061 tcctgcgcca gttcctcgcc ctcatccagg cgaccctgcg caccaactgg ttccagcgtg
    18121 gtgcggacgg cgcgcccaag gcctacctct cgttcaagtt cctgccggcg aagatcccca
    18181 acctgccgca gccgctgccg atgttcgaga tcttcgtgta ctcgccgcgc ttcgagggtg
    18241 tgcacctgcg cggcggcaag gtcgcacgcg gcggcctgcg ctggtcggac cgcatggagg
    18301 acttccgcac cgagatcctc ggcctggtga aggcgcagat cgtcaagaac gcggtgatcg
    18361 tgccggtggg ctcgaagggc ggcttcgtgg tcaagtgccc gcccgcggag ggcgggcgcg
    18421 aggcgctgct cgccgagggc gtggcctgct accgcaactt cctgcgtggg ctgctcgacc
    18481 tcaccgacaa cctggtgcag ggcgcggtgg cgccgcctgc ggacgtggtg cgccacgacg
    18541 aggacgaccc ctacctggtg gtggcggccg acaagggcac ggcgagcttc tccgactacg
    18601 ccaaccaggt ctcggccgag tacggcttct ggctgggcga cgccttcgcc tcgggcggct
    18661 cggtgggcta cgaccacaag aagatgggca tcaccgcgcg tggtgcctgg gaggcggtca
    18721 agcgccactt ccgcgagatg ggcaaggaca tccagcagca acccttcagc gtcgccggca
    18781 tcggcgacat gtcgggcgac gtgttcggca acggcatgct gctgtcgaag cagatccgcc
    18841 tggtggcggc cttcgatcac cgccacatct tcatcgaccc cgatcccgac ccggcacgct
    18901 cgtgggagga gcgcgcgcgc atgttcgcgc tgccgcgctc gagctgggac gactacgacc
    18961 gcacgctgat ctcccagggc ggcggggtgt ggccgcgcag cgccaagtcg atcgcgctgt
    19021 cacccgaggc gcgtgcggcg ctcgacatcc aggccgggag cctgaccccg accgagctca
    19081 tccgcgccat cctcaccgcg ccggtcgagc tggtctacaa cggcggcatc ggcacctaca
    19141 tcaaggccgc cagccagacg gacgccgcgg tgggcgaccg cgccaacgac gcggtgcgcg
    19201 tcaacggcgg cgagctgcgc tgcaaggtct tcggcgaggg cggcaacctc ggcgccaccc
    19261 agctcggccg catcgagttc gcgctcgcgg gcgggcgcat caacaccgac gcgatcgaca
    19321 actcgggcgg ggtggactgc tccgaccacg aggtcaacat caagatcctg ctcggcggcg
    19381 tgatcgccga gggcgagctc accctgaagc agcgcaacga gctcctcgcc gacatgaccg
    19441 acgaggtcgg catcctggtg ctgcgcgaca actacgccca gacccaggtg ctgtcggtca
    19501 cccgggcgcg cggcgtggcg ctgctcgacg agcaggccga gttcatccgc cgcctggtgc
    19561 aggccgggcg gctcaaccgc aagctcgaat acctgcccga cgacgaggag atcgccgagc
    19621 gcaaggcggc ggggggcggg ctcaccagcc ccgagctcgc ggtgctgctc gcctacagca
    19681 agatcgagct ctacgacgag gtgctcgcct ccgacgtgcc ggaggacccc tacatccgca
    19741 ccgcgctcga gcgctacttc ccggcgccgc tgcgcgagcg cttcccggcg cagatccagg
    19801 cccatccgct gcgccgcgag atcatctcga cgcacgtggt caacagcatg atcaaccgcg
    19861 tcgggcccac cttcgtcagc cggctcaagg ccgagctcgg cgcctcgccg gccgacgtgg
    19921 tgcgcgccta catggcgacc cgcgaggtct tcgggctggt ggcgctgtgg cgcgagatcg
    19981 aggcgctcga caaccgcatc gccgacgcgg tgcagaccga gctgatccag gagtccggtc
    20041 gcctggtgca gcgcggcacc ttgtggttcc tgcgtcaccg ccgctggctg gccgacctgc
    20101 aggcgacgat cgcgcacttc tcgcccggcg tggcggccct ggccgagggc ctcgccgact
    20161 acgtcgcccc cgcctatcgc gccgagctcg acgccgcggt ggcgcgccgg gtggagcagg
    20221 gcgtgcccga ggcgctggcg aagcgggtgg cggcgctcga ggagctgtat tccgcgctcg
    20281 acctggtcga ggtggcagtg gagcaggggc gcgacgaggc cacggtggcg cgggtgtatt
    20341 tcgccctcgg cggcgagctc gacctgcact ggctgggtgg ccaggtgtcc ggcctgccgg
    20401 cggacacgcg ctggcagagc ctggcgcgcg gcgcgctgcg cagcgacctg tcctcgctcg
    20461 cccgcgagct caccagcgcg gcgctgcgca acgcgcccgc gggggccgac acccaggacg
    20521 tgctgcgtgc aggacgggaa cgcgccgcgg tcccgctcga gcgctaccag cagctgctcg
    20581 ccgagatccg cggcgcgccg gcgatcgaca tggcgatgct gtcggtgctg ctgcgcgagc
    20641 tgcgtggcat ggcctgagcg atcgcgcgcg cgacgccccg atgcgcccgg actgctgacg
    20701 cggttcgggc gcttcggtta tcatcgcgct ttcccgcagt actgctccca tgaccaaata
    20761 cgtcttcgtc accggtggtg tcgtgtcctc cctgggcaag ggcatcgccg cagcgtccct
    20821 cggggcgatc ctcgagtccc gcggcatcaa ggtcacgcac ctcaagctgg acccctacat
    20881 caacgtcgat ccgggcacca tgagcccgtt ccagcacggc gaggtcttcg tcaccgaaga
    20941 cggcgccgag accgacctcg acctcggcca ttacgagcgc ttcaccagcg ccaagatgag
    21001 caagcgcaac aacttcacca ccggccagat ctacgagtcg gtgctgaaga aggagcgccg
    21061 cggcgagtac ctcggcaaga ccgtgcaggt catcccgcac atcaccgacg agatcaaggc
    21121 ctacgtcaag cgcggcgcgg aaggcgccga cgtcgcgatc gtcgaggtcg gcggcacggt
    21181 gggcgacatc gagtcgctgc ccttcctgga ggcgatccgc cagatgggtt tcgaggaggg
    21241 ccgccacggc acctgcttca tccacctcac gctgctgccc tacatcccta ccgccggcga
    21301 gctcaagacc aagccgaccc agcactcggt caaggaattg cgcgagatcg gcatccagcc
    21361 cgacatcctg ctgtgccgtg ccgaccgctc catcccggcc gacgagcgcc gcaagatcgc
    21421 cctgttctgc aacgtcatgc ccgaggccgt catcgagtgc ctggacgcgg actcgatcta
    21481 caagatcccc ggcatgctgc acgaccagat gctcgaccag atcgtctgcc acaagctcga
    21541 catcctcgcg cgcgcggccg acctgtcggt gtgggagaag ctcatccacg cgctcgagaa
    21601 ccccaggcag acggtggaca tcggcttcgt cggcaagtac gtcgatctca ccgagtcgta
    21661 caagtcgctg atcgagtcgc tcaaccacgc cggcatgcac accgagtcga aggtcaagat
    21721 ccactacatc gactccgagg acatcgagcg cgacggctgc ggcgtgctgg cgtcgatgga
    21781 cgccatcctg gtgccgggcg gcttcggcaa gcgcggcacc gagggcaaga tcgccgccat
    21841 ccgctacgcc cgcgagaaca aggtgcccta cctgggcatc tgcctcggca tgcagctcgc
    21901 ggtggtcgag ttcgcccgcg acgtcgccgg catggacggc gcgcactcga ccgagttcga
    21961 gcgcgacacc aagtaccccg tcatcggcct catcaccgag tggaaggacc gcagcggcaa
    22021 gatcgagaag cgcaccgagg agtccgacct cggcggcacc atgcgcctcg gcggccagct
    22081 ctgcctgctc aaggaaggca ccctggcgcg ttcgatctac ggcgcggccg aggtcatgga
    22141 gcgccaccgc caccgctacg aggtgaacaa cacgctgctt gccaggctcg aggacaaggg
    22201 cctggtagtg tcgggccgtg cgcccgtcac cgacctgtgc gagatggtcg agctgcccgc
    22261 cgacgtgcac ccgtggttcg tcggctgcca gttccacccc gaattcacct ccaacccgcg
    22321 caagggtcat ccgctgttca ccgcctacgt gaaggcggcg atcgaacgca agcaggctga
    22381 gtcctcgagg agcgaagcat gaatctctgc ggtttcgaag tcggcctcga caagcccatc
    22441 ttcctgatct ccggcccctg cgtggccgag tccgagcaga tgtgcctgga catcgccggc
    22501 cagatgaagg aaatctgcgc cgagctgggc atcccctaca tcttcaaggc ctcctacgac
    22561 aaggccaacc gcagctcggg caagagcttc cgcggccacg gcatggacgc cgggctgaag
    22621 atgctcgagg cggtcaagaa gcagctcggc ctgccggtgc tgaccgatgt gcacacgatc
    22681 gaggagatcc cgctcgtggc ctcggtggtc gacgtgctgc agaccccggc cttcctgtgc
    22741 cgccagaccg acttcatcca cgcggtggcg gccagcggca agccggtgaa catcaagaag
    22801 ggccagttcc tcgcccccgg cgacatgaag aacgtcgccg acaaggcgcg cgaggccaac
    22861 ggcggcgccg acaccatcat ggtgtgcgag cgcggcgcct ccttcggcta caacaacctc
    22921 gtctccgaca tgcgctcgct cgcgatcatg cgcgacaccg gctgcccggt ggtgttcgac
    22981 gccacccact cggtgcagct gccgggcggg cagggcaccg cctcgggcgg ccagcgcgag
    23041 ttcgtgccgg tgctggcgcg tgccgcggtc gcggtgggcg tggcgggcct cttcatggag
    23101 acccaccccg acccggccaa ggcgctgtcc gacggcccca acgcctggcc gctgccgaag
    23161 atgaaggcgc tgctgagcgt gctcaaggac atcgacagcc tggtcaaacg ccagggcttc
    23221 ctcgagacca cgctctgaga acccgttttt cgggaacgcg gctgccggcg ggctgatgtg
    23281 cgccatcagc ttgccgccgc tcacgaggcg gtcatccggt gcgagcatgc tccccgccgg
    23341 atcgcgttcc cgcgtgatcg atccgaaact ccgtaactgc tacaggactg gacatgagtg
    23401 caatcgttga tgtgatcgcc cgcgagattc tcgactcccg cggcaacccc accgtcgaag
    23461 ccgacgtgct gctcgaatcg ggcgtgatgg gccgcgccgc ggtgccgtcg ggcgcctcca
    23521 ccggctcgcg cgaggcgatc gaactgcgtg atggcgacaa gtcgcgcttc ctcggcaagg
    23581 gcgtgctgcg cgcggtcgag aacgtgaaca ccgagatcgc cgaggcgatc atcggcctcg
    23641 acgccgagga gcaggccttc atcgaccgta ccctgatcga gctcgacggc accgagaaca
    23701 agtcgcgcct gggcgccaac gccatgctgg cggtgtcgat ggccgtggcc aaggccgccg
    23761 cggaagaggc cggcctgccg ctgtaccgct acttcggcgg ctccagcccg atggtgatgc
    23821 cggtgccgat gatgaacgtc atcaacggcg gcgagcacgc caacaacagc ctcgacatcc
    23881 aggagtgcat gatcatgccg gtgagcatga ccagcttccg cgaggccctg cgctgcggcg
    23941 ccgagatctt ccaccacctc aagaagatcg tggacgccaa gggctacccc accacggtcg
    24001 gcgacgaggg cggctttgcc cccaacgtct cgggtaccga ggaagcgctc aacctgatcc
    24061 aggaagccat cgtcgccgcc ggctacgtgc ccggccagga cgtgctgctg gcgctcgact
    24121 gcgccgcctc cgagttctac aaggacggca agtacgagct caagggcgag ggcctgtcac
    24181 tgaccgccga gggcttcacc gactacctcg agaccctgtg cgacaagttc ccgatcgtct
    24241 cgatcgagga cgccatggcc gagggcgact gggacggctg gaagatcctc accgagcgtc
    24301 tgggcaagcg cgtgcagctg gtgggcgacg acctcttcgt caccaacacc cgcatcctcg
    24361 cgcagggcat cgagcagggc gtggccaact cgatcctgat caagatcaac cagatcggca
    24421 cgctgaccga gaccttcgcc gcggtcgaga tggccaagct cgccggttac acggcggtga
    24481 tctcgcaccg ctcgggcgag accgacgact cgaccatcgc cgacatcgcc gtgggcctgc
    24541 gcgcgatgca gatcaagacc ggctcgctga gccgctcgga ccgcatctcg aagtacaacc
    24601 agctgctgcg catcgaggaa gacctcggcg acaccgccaa ctatccgggc aagcgcgcgt
    24661 tctacaatct gcgctgaaca ccccgctgcg ctgatccgca gcttccggaa ggccggcggg
    24721 cgacccgccg gccttcgtcg tgaatgcgcc tgaacctctc cgatacccgt ctccatgcgc
    24781 tggccgatcc tgatcctgat cgcactcgtc gtgctgctgc agtacccgct ctggctgggg
    24841 aaaggcggct ggctgcgcgt ctgggaggtg gaccgccagc tgcacgcgca gcgcgaggag
    24901 aacctgcgcc tcgagcagcg caacgccgcg ctcgcggcgg aggtgaacga tctcaagtcg
    24961 ggcaacgagg cgatcgagga gcgcgcgcgc ttcgagctcg ggctcacccg gccgggcgag
    25021 atctacgtgc agatcccgca gcgctgaggg cgcagtccgc gccgcccggc gcgcgctcag
    25081 ttgctcgcca gcagtgtgcg cgcgccgtcg atgcgctgcg cgaagtagcg gttggcgagg
    25141 cgctccaccc gcacccgccc gcggctgttg ggcgcatgca cgaagcggcc gtcgccgatg
    25201 tagatcccca tgtgcgaatg ccggcgcttg agcgtgttga agaacaccag gtcgcccggg
    25261 cgcagctcgt cgacctcgat cgggcgggtg cgctcggcga tctgcgcggc gttgtgcggc
    25321 agcctgcggc cgctgatgtg ctccacgatg taggccacca tgccgctgca atcgagcccc
    25381 gcgtccgggt tgcgcccgcc gaagcggtag ccggtgtcga gcaggccgag cgcgaacagc
    25441 accatctcct gcgtctggtg ctcgccctcg agcgagaagt agtggccgct cggtgcggtg
    25501 gtgcgcggcg gcggggcggg gctggcgacc ggtgtggggg tggtgctgca gcctgccagc
    25561 agcgcggcca cccctgcagc ggcggccagc agcatccgac gccgggcgcc gtgatgcgaa
    25621 tgttgcccgg aggaagggaa ggcgcgaggc agcgactcgg gactcatggc gcgatccgat
    25681 gcggaaagga ttcgctccgg agtatgtcag gagctgccgc aacgggcaag gttcgcttgc
    25741 ggatcaggag cttggagggg ttttctcgaa ggcggctgaa gtcgggcccg ctcgcggacc
    25801 cgccgtcttc aatcgagcag ctcgatgcga ccgctcacgt gcaccgacac gcggctctcg
    25861 ccaccttcga gcggcgcggg ggcggcttcc gcagccatca ccgcggcgcg catgcgcggc
    25921 atcggcggcg gctgcaggcc gtggtcgccg accgccaggt gggcgatgcg gtagcgtcgg
    25981 ccgagggtgt cggcgatcag ctgcgcgcgg gtctcgaacg cgcgcagcgc gtcgacggtg
    26041 acgtcggcca ccgccttcct gcgcgtctcg ggggccggtt ccatggtgag gtgcgcgagc
    26101 gccaggctct gctgcagctt gccgacgagc tccgacatcg ccgccgtgtc ggtgctctcg
    26161 aggcgcaact cggagcgcat ccgccaggcc gtgatgcggc cctggccatc cttgccgtaa
    26221 accggccagg tggagacgtt gccgctctgc accttgacgg caccctgtgc gcgcgcgagc
    26281 tcgagcgcgg cggcgatgtc gcgattgacc tcgcgtgcca ccgcagccgc gctggtgccg
    26341 ctgcgttcgg cgtagagcac cgcgaccgcg aggtcgttcg ccgccgcgcc gccggcctcg
    26401 gccgagagtt ccacggtggg cggggcgggg gtgtcggcgg caacggccgc ggccgactgc
    26461 agcgccgtga gcgtggcgag ggtggcgagc gcggcgcgca tcactgctcc ggctgcgcga
    26521 tcacgctgga cggttccagc gcacagaggc ggtcggcgta gaggcgggcg ttgtccacgt
    26581 agttgtgggc attgaccacc aggttctcga cctcggtatc gctcagggtg cggatcaccc
    26641 ggccgggcga gccgaccacc agcgcgcggt cggggatgac cttgccttcg gggatcaggg
    26701 tgttggcgcc gatgatgcac tgcttgccga tcaccgcgtt gttgaggatc accgcgttga
    26761 tgccgatcag gctgccgtcg ccgatcgtgc agccgtgcaa catcgccatg tggcccacgg
    26821 tgacgtggcg accgatggtc agcgggatgc cgtcatcgtt gtgcagcacc gagccgtcct
    26881 ggatgttggt gtcgtcgcca atcgtgatcg ggtcgttgtc gccacggacc acgacgttgt
    26941 accagatgct gacgttgcgg cccgcagtga cggacccgat gaccgttgcg ttgtgggcga
    27001 tccagctacc ttcgccgaag ctcggccgac ggtcgcccag ggcatagatg ctcattttcg
    27061 ttctcgctgt cgatgtctcg cgccgatgcc gtgcagcgcc aggggggagg catcatagca
    27121 agcacctcgc gcactgcaaa cagcgcccgt gccgtgaatg tcgccgatcc ggcgcgcttt
    27181 tgccgatttt gagcggtctg ccggcgagtg atacgatgcg cccgcccctc aggaagcctc
    27241 tatgctcagt tatcgtcacg cctttcacgc cggcaaccac gccgacgtcc tcaagcacct
    27301 cgtcctgatc gaactgctcg actactacgg ccgcaaggac aagccgtggt actacatcga
    27361 cacccatgcg gggggcggct gctacgcgct cgacagcgag caggcgggga agacggccga
    27421 ggcggcggac ggcatcggac ggctgtgggg gcgcgaggac ctgccgccgg cggtcgcgag
    27481 ctatgtcgag gcggtgaggc agttcaaccc gcagggtcgg ctgctgttct acccgggctc
    27541 gccggcgctc gcgatgacgc gggcgcgcgt ccaggaccgc ctgcgcctgt tcgagctgca
    27601 cccggccgac ttcgaatccc tgcagcgcac cttcgcgagc gagcaggagc gcgtgcaggt
    27661 gcgccgcgcc gacggcttcg ccgcgctcaa gagcctgctg cctccgccct cccggcgcgc
    27721 ggtggtgctg atcgacccgc cctacgaggt caaggacgac taccgccgcg tggtggatac
    27781 catgcgcgac gcgatgcggc gcttccccac cggcacctac gtggtgtggt acccgatgct
    27841 tgcccgcacg gaggcgcgcc agcttcccga gcgcctcgcc gagctcggcg ccgagagctg
    27901 gctggacgtg cgcctggcgg ttcgcgacgc gccgcgcgac ggcatcggca tgttcggcag
    27961 cgggctctac gtgatcaatc cgccctgggt gctgccacag cgcctcgagg cggcgctgcc
    28021 ctggctggtc gagcgcctcg gtgtcgatgg cggcgccggc ttcgacctcg agcatcacat
    28081 cgaatgaacc cgtccggcga catcgcaggc gagggcgcag cggccgcgca ggaggccgcc
    28141 ccgggcgcga ccggcgcgcc gtccgacgcg ctccacgagc tgcgcgacgc gatgcggcag
    28201 ttcgccgccg agcgcgcgtg ggagcccttt cacaccccca agaacctcgc gatggcgctc
    28261 gccggggagg cgggcgaggt catcgagcac ttccagtggc tcaccgccga gcagtcgatg
    28321 gcgctgccgc ccgcgagccg cgaggaggtc gccttcgagc tcgccgacgt gctgctttac
    28381 ctggtgcggc tgggcgacgt gctcgggatc gatctcgccg atgcggcgcg gcgcaagatg
    28441 gtgctcgacg cgcagcgcta tccggtcgag cgcgcccgcg gccgcgcgga caagcacgac
    28501 cgcctgtagg cgagtgccac gccgcctctt cgggacttca ttcacgttgg gccgcggcaa
    28561 gatttctgaa acaatacggg ctttcctgta acacggactt tcatcgtgga tctgcagcac
    28621 atcagcgaca tcgagagggc ggcgcaccag ggccggggcg aggtcttccg cctcggcatg
    28681 ggcgtgctct tcatcgtcgg ggtcatgttc tactcggcgc tcagcggctc cggggagggc
    28741 aacctgaccc tggtcatggc ggcgatgatc ggcggctaca tggcgatgaa catcggcgcc
    28801 aacgacgtcg ccaacaacgt gggtccggcg gtgggctcca aggcgctgac actcgcgggt
    28861 gcgctcgtca tcgcggcaat cttcgaggct gccggcgcgc tcatcgccgg tggcgaggtc
    28921 atcggcacca tccgcagcgg catcatcgac cccgacctca tcaaggactc cgacaccttc
    28981 gtgtggatca tgctggcggc gctgctcgcc ggcgcgctgt ggctgaacct ggcgaccgcg
    29041 gtcggcgcgc cggtgtcgac cacgcactcg atcgtcggcg cggtgctggg tgccggcatg
    29101 gctgccgccg gcccggccat cgtcgactgg tccaccatgg gcaatatcgc ggcgagctgg
    29161 gtgatctcgc cggtgctcgg cggcatcttc gccgccgcct tcctgtatct ggtcaagcgc
    29221 agcatcacct accaggtgga catggccgcg gccgcacgcc gcaccgtccc gctgctggtc
    29281 gggctgatgg cgtggacctt cgccagctac ctgatcctga aggggctcaa ccgtgtctgg
    29341 aaggtggatt tcctgtcggc catggtgtac ggcgccgtgg tcggcgcgct ggtgttcgtc
    29401 gtggtgcgca aggtcctgca cggcaacggc ggtatcgtcg ccaacaccaa ggcgagcgtg
    29461 aatcggctct tcaccgttcc gctgatcttc gccgcggcgc tgctcagctt cgcccacggc
    29521 tccaacgacg tcgccaacgc cgtcggtccg ctcgccgcga tcgtcgatgt ggtcagctcc
    29581 ggtggcgtgg tgcacaagga cgcgaccatc cccacctggg tcatgatggt gggcgcgatc
    29641 ggcatctcgc tcgggctggc gctgttcggg cccaaggtga tccgcacggt cggctccgag
    29701 atcaccgagc tcgaccagat gcgcgcctac tgcatcgcga tggccgcgac cctgaccgtg
    29761 atcgtcgcca gccagctcgg cctgccggtg agctccaccc acattgcggt gggcggggtg
    29821 ttcggggtgg gcttcctgcg cgagtacctc aagagcaact acgaccgcat ggtggccgag
    29881 atcaaggccc atcaccccga aggcgacctc gccgcgatcg aggccttcat cgcgcgcttc
    29941 gagaaggcct ccatcgagga gaaggggcag atgctcgccg acctcaagga gcgctcgaag
    30001 aacgcggacg acccggcgca cttctccaag ggcgagcgta agggcctcaa gaaggtctat
    30061 cgtcgcgagc tggtcaagcg ctcgcagctg atgcgcatcg ccgccgcctg ggtcatcacc
    30121 gtgccggctt cggcgctgat ggccgcggtg ctgttcttca tgatccgcgg gatgatgctg
    30181 ccctgagcgg cgtgtgcgcg atcccggagg ccgtggcgtg agcttcgtcg agctgctcgg
    30241 cttcctcgcg ctcggcgcga tcgtgtggta ctggttcgac agcctcaagg cgcgcgagat
    30301 cggcgtcgac gccgcgcgcc gcgcctgcgc gcgcgagggc gtgcagttcc tcgacgagac
    30361 cgtggtgggg caggggctgc gcctggcgcg cgacgacgac ggccgcgtgg tgctgcggcg
    30421 cggctacgcc ttcgagtact cggtgggcgg cgacgaccgc aacgccggca gcgtcgtgct
    30481 ggaaggccgc gaggtggtgc tggtggatgt ctccgcgcac cggctcgcgc gccgcgcggt
    30541 ggtcatcgag ctgcacccgc gcgatccgtc ggcctagcgc cggcgctcct cgatcgcgcg
    30601 caggaactcg ctgcgcgcct gctccgagcg ttcgaactcg ccagcgaagg cctgcgtgat
    30661 gacgcgctcg tcgccgcggc ggtcctcgcc gagcagcagg cagagctgct cggcctcgat
    30721 cacgcaggcc gcgccggcag cgtggccgtg gtgcatcagc gcgtcggcga tgtcgcgcgt
    30781 catccattcc tggtaggtga agcggtggcc gatcgcgtcc accaggcgcg cgatgcgccc
    30841 gaagccgtgc aggcgcccgc cgggcaggta ggcgacatgg gcgactccgc ggaagggcac
    30901 gaggtggtgc gggcacaccc catgcaccgc gatgccgcgg atcaccacca tgtcgcggcg
    30961 cgcgtcctcg aagccgtcgc cgagcacctc ggcggggtcg agttcgtagc cgccgagcag
    31021 ccggcgctgc cagagctcgc gcacgcgctg cgcggtgcgg ccggtgtggg cgttgtcggg
    31081 ggcgatgccg caggcacgca gcaggtcgcc gacggctttc tcgaaggcgg gcgcgtcgaa
    31141 ggcgccgcgg cgcggaatgc cgacgccgtc ggggcgggga gcgtgggggt ggtcgtgacc
    31201 gcaggggtcg tgcgcgggag ggctcatggc ggcgtccggt gcggtgcgct gcggcacccg
    31261 aaccggcatg atacccgcaa gcccgctcag gcgatgaaca ccgggtccga gaacaccagc
    31321 gtgccgtcgg cgcgcatcat cagattgttg gcgttgagga tgtcgggcag gacctggtat
    31381 tcctcgacga agtcggacag ggcgcgcagg gcttcctgca ggctgtcgcc gatcttgagc
    31441 gggtcgaccg tgaggtgata gagcgcgatc cgccccatgt cggcgccgag ccggctccac
    31501 tgcgcgcacg ccgaccagta gcactcgatc aggcggcggg agagttcggc cgcaggcgag
    31561 ccctcgacga gcggatagag gcgctccatc tcgatgagat ggaaggggta gcccgactgc
    31621 gcgcggccga tcacgccatg gtccgcgtaa acgatcggga agtgcggccc gcgcgggcgg
    31681 tcttctgcag tgtagaggaa atagtcggcc ggggagctga cgaccttgta gacccgctcc
    31741 ccgtcgccct tgtcgatcac gatcgagtac tcgccgcggc cgatctcctt cttgccgtcg
    31801 agcagcgcat gcgagggcac ggggtcgggc agcaggatgg cctgccggcc gagcatcgca
    31861 cgtgccgcgt ccatgtcgat catgatgccc ccgggcctta cgccatgatg ttgtagccgg
    31921 cgtccacgaa atgcacaccg ccgctgacca ggcggccggc gtccgagacc aggaaggcgg
    31981 tcagcgcgcc gatgtcctcg ggcgtgacca gggcgtgcat cggcgagcgc tcgaccgcgg
    32041 ccgccatgag gccgtcgaag ccggcgatgc ccgatgcggc gcgcgtcatc agcgggccgg
    32101 gagagaccgc attgacgcgg atgcccttgg cgccgagctc ggccgccatg tagcgcgtgg
    32161 cggcctccag cgccgccttg cacaggccca tcacgccgta gttggggatg accttctccg
    32221 agccgaggta ggtcatcgtc accagggcgc cgccaccggc cttctcgagc aggggttcgg
    32281 ccttcttggc caggcgcacg aaggagtggg tggacacgtc catggcgagc gcgaagccgt
    32341 cggccgaggt atcgaccacg cggccgtgca ggtcgtcgcg cttggcgaag gccatgctgt
    32401 ggatggcgaa gtcgagcttg ccgtggcgcg cctcgatcgc ggcgaaggtg gcgtccatgg
    32461 tctcggggcg ggtgacgtcg agcaggaaca cgtcctccac gccgaggcgg tggatcaccg
    32521 gctcgatgaa ggcgcgcgtc ttctcgttct ggtaggtgat gatcagcttc gcgccggcct
    32581 gggcgcaggc ctcggcgacg ccggtggaga tcgacttctc gttggcgatg ccggtgatga
    32641 ggccgacctt gccctcgagg ttgatgatgg gggtcatgac ggattcctgt tcgcgggttg
    32701 atgttgttgc ggcgcaacag cggcaagcat aagccgcgct ttgcgacgga aatgtgatgg
    32761 ttcgtgaaat cggatacgca gcggtatcgg tgccggtaca gtatattgcg cattgcagca
    32821 tccacaaacc gccggcagcg gccttgttcg ccggagcagg aaacatgaca cgaaacgcat
    32881 acatcttcat ggacttcgac ggcgtcaccc atccctgggg cgaggtcgag gatttccgtt
    32941 gccttccgca tatcgaggcg gtggtgcggg agttccccga ggcgcgcatc gtgatcgcct
    33001 ccgactggcg catgctgttc tcgctgccca agctggtcgc ccgcttctcc gaggacatcc
    33061 gcccgcagat cgccggcgcc acgccgcacc tgctgcccaa gaccggtgcc gagctgcacg
    33121 gcctgcgcga gcgcgaggcc atggcctggc tgcgccagca cggcgccgac ccggccgagg
    33181 cggcgtggtg cgcgatcgac gatgcgccgg gcaactggct gtcgcgctcg cgcctcgtgc
    33241 tgaccgactt caagcgcggc ttcaccgccg aggatgcggt cgcgctgcgc cgcatgctgc
    33301 agggcttccg cgacggcgtg cgcaaccagg tcgggcaggt cgtgcattcg ctatgggcgc
    33361 gcgacagcgc ctgatccggg gagacaccat gaatccggcc gagcagaccc tgccgcccga
    33421 cccgctcgcg cgccatgtcg acctcgcgac ccagcgccag gcggcgcgcc tggccgaaga
    33481 gagcttcgcg cgcctgttcc ggctcagcgt cgccgagggc gacgctgcgc ggctgaaggg
    33541 tgtggagcag ctgcgcgtcg acctcgccga ctgggtggcc gccgcggccg acgccgaggc
    33601 gcaggccttg cgcctggcct tggtcctcgc cggcttggac cagtgggggc tggcgtggag
    33661 ccgcgccttc ggcctggtgg cgatccccgc gctcaccgag ctcatcggtg cgctgcgcac
    33721 cggcctcgac gaggccgccg aggcgcgctt cctgcgccac ttcgagggca tcgccgcggc
    33781 cgaggagaac gccatcgact tcaaggtcga gctgcgccgc ggcctgcacc tggcgctgtg
    33841 gcacgcctcg atcgccaccg gacaccgtga cgaggccctg cgtctcgccg ccgagctggg
    33901 cagccagttg ctcgcgctca cccgcagcat gccggtggcg ggctggcggc tggtggccga
    33961 cgcgctcgcc ttcatccaga tccgctgcct ggccgaaggc ctcgccgccg agggcgtggc
    34021 gcaggaggcg acgcaggcct tgttcggtgc gctcgcccgc gagctgccgg cgccgcagcg
    34081 cgacctcgtg atggcgcact ccgcgcgtgc ggtgatggct tggcagcagg ccggccgcgc
    34141 ctcgcagcag gtgcactgat ggcgctcaag gccacggtct tcaaggccga catccaggtc
    34201 gccgacatgg atcggcacca ctacgccgac tactcgctca ccctcgcgcg ccacccctcc
    34261 gagaccgacg agcgcatgat ggtgcgcctg ctcgccttcg cgctcttcgc cgatccggcg
    34321 ctcgccttcg gcaagggcct gtgcgccgac gacgagcccg acctgtggca gcgggacctg
    34381 accggcgcga tcgagcgctg gatcgacgtc ggccagcccg acgacaagtg ggtgcgcaag
    34441 gcctgcgggc gcgcgcgcga ggtggtgctg ctggcctacg ggcgggcgct cgaggtgtgg
    34501 tggagcgggg tgcgcggccg cctcgagcgc cacggcaacc tgcgcgtcct cgaactcgag
    34561 cgcgaggcca gcgccgagct cggccgcctc gccgaacgca ccatgcgcct gcagttcacc
    34621 atccaggacg gccacgtgct ggtgaccaac ggccgcgaca ccgtgtcgct cgagccgcgc
    34681 aagctcgccg gctgaagcgc tcggcggaca tggcgcgcgc cccgcgcgcc ccgcgcgctg
    34741 cgcccgcgcg cgtcagcgcg ggcggtcgag caggaaggcc gccaccctct ccgcggtcgc
    34801 ctgcggatgc tccagcatga agcagtgccc gccctccacc tgcacgcatt tcacgttggc
    34861 cttgcccgcc gcccagcgcg tgaccgagcg ccgcgcgaag gcgaaggtgt cgcgtccgtg
    34921 cagcgcgagc accgggtgct cgatgcgctc gagcgaggac cacagccggc gcgggtagga
    34981 ggcgaagatc tcggcttcgc gcgtgggccg gcacttgagc tccacgccgc cgccggggac
    35041 atcgcgcagc gcatggtcga tgtaggcctg gaaggagtcc tcgctccagc cgcggaacac
    35101 gccgcgcccg tgcaggcccg cgtgcgcggt ggcgcggtcc ggccagtggt ggcggcgcgt
    35161 gcgcgccttg gcggcgagct tgttgcgcga ggccaggccg acgagatccg agagtgccat
    35221 catgccgatc atcgccgggg tgaacagcac cgggtcgagc agcacgccac ggctgaaggc
    35281 ctgtggatga tgcgccagca tcaggcaggt gagcacgctg ccgaagctgt ggcctgcggc
    35341 atgcaccggc accgcgccga agcgcgccgc gtgcgcgagc caggcttcgg cggccatctc
    35401 ggcggcatgg ttccagccgc ggaagcgact gccgtggtcg ctgtcgccgt ggccttgcac
    35461 gtccgacagg aagaggtcga aatgctcgct caggtggcgg agcatcggcg cataggtcag
    35521 cgagctcagc ccgttcccat gcaggaaatg cagcaccggg cggccgctcg gcgggctgtg
    35581 gtggccgcgc agcgtgaagc cggcggtggt gtggtgagtc cagctttgca gcttcatgat
    35641 tcggcatcaa ccacgcgcgc agcagtggcg gtggcgggtt tcgggttatc gggccgatcg
    35701 gattggcggg cagcggccgg ggctcgcgca tgccgcgtcg tcggcgaaag gtgcgtgagt
    35761 ctgccacgaa aaccagcccg ggatgtgctc gaccggcatc gggcgggcga tgccgaagcc
    35821 ctggccgagc ctgcagccga gatcgagcag ggcctcggcg tgggcgggcg tctccacgcc
    35881 ctcggcgatc acctcgcgac cgaaggtgcg cgcgagctgc accacggcgc cgacgatcgc
    35941 acgcgcttcg ccgtcctcca gcatgtcgag cacgaagctg cggtcgatct tgaggcggtc
    36001 gaagggcagc tggcggaagt ggcgcagcga ggcgtagccg gtaccgaagt cgtcgagcgc
    36061 gatgcgcacg ccgaggcggc ggcaggactc gagcacgtcc atcgcaagca ccatgtcatc
    36121 gagcgcggtg gattcgagga tctcgagttc caggcgcgcg ggcgggatgt cggggtggcg
    36181 ctcgagcgcg ctgcgcacgc tggcgacgaa gcccgcctgc atcagcgggc gggggccgat
    36241 gttgacgctg acaccgatgt ccagcccggc ggcgcggcag cgctcgagcg cgccgagcgc
    36301 gtggtcgatc acccactggc cgagccgggt ctcgagctcg gtgccctcga gatcggnnnn
    36361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    36421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnntggt cgatcaccca ctggccgagc
    36481 cgggtctcga gctcggtgcc ctcgagatcg ggcaggaagt cgcccggaag cagcaggcca
    36541 cgttcgggat gttgccagcg cagcagggcc tccatgccga gcgggcggcc gtcggccatg
    36601 tcgacctggg gctggaagtg cagcacgaac tcgtgccggc gcaaggccag ctcgaggcgc
    36661 tcgaggcgtt ccttgcgcac gcgctgctgc tcctcgacgc tggcgtcgaa gaactggatg
    36721 cagttgcgcc cgcgctgctt ggcgcggtac atcgcctggt cggcgtggcg cagcagggtg
    36781 tccgggtcgg cgtcgtcctc ggggaagagg gtgacgccga tgctcgccga caccgacacc
    36841 tggcgggtgg cgagcgcgat cggcatgcgg atggcgtcga gcacgcgctc gagcacacgc
    36901 tcgccgtcga tgtcctcgag cagcagcacg aactcgtcgc cgccgacgcg ggccacggtg
    36961 tcgctcgcgc gcaggatcgt ggcgagccgg tcgacgatgc cgaccagcac ctggtcgccg
    37021 gcctcgtggc cgagctggtc gttcaccggc ttgaagccgt cgaggtcgat cacgcagacc
    37081 gcgagcggcc gcccggtgcg gcgcgagtgc gcgatcgcct ggcgcaggcg gtcgtcgagc
    37141 aggcggcggt tgggtgcgcc ggtgagcggg tcgaagtagg cgatgcggtt gagctcttcc
    37201 tcgtgcttct tgagccggct gatgtcggag aacatcgcca gatggtggat cacccgcccg
    37261 cgcgcgtcgc gcacgcggct gatcgacagc acctcggcaa actcgccgcc gtccttgcgc
    37321 cggttccaca gctcgccctg ccagtggtcg tgctcctcga gcgcctgcca catcgcgcgg
    37381 tagaactcgc gcccctggcg gccggaggcg agcatgccgg ggtcgcggcc caggctctcc
    37441 tcgcggctgt agccggtgat gcggcagaac gcggggttga cgtcgacgat gcgattgtcg
    37501 gcgtcggtga tcaggatggc ctcgtagctc gacgagaaca cgctcgcggc caggcgcagg
    37561 cgctcctcgt tttccttgcg gcggtcgatg tcgacctgtg cgccggtcag cagcagtgcg
    37621 cgcccgtcgg cgtcgcggcg cacggcgagg gcgcggtcgt gaacccagat ccagttcccg
    37681 tcgcggtggc gcaggcgcag gtcgtgctcg tagaaggcgg tctcgccgcg gatgtggcgc
    37741 tcgagttcga gctcggcctc ggccaggtcg gcggggtgca cgcgctcgcg ccaggatgcg
    37801 cgcccgagcc cggtgcaggc ctcgggcggg agccccagca tcgccgccca gcgcgcgtcc
    37861 accctccatt ccccggtctc caggttccac tcccaactgc cggcctgggt ggcctcgacc
    37921 acgttgcgca ggtgatggcg atcgagttcg acttccgccg ccagccggcg cgcggcggcg
    37981 ttggcctgcg acagcgccag gttgcgctgc gccagacgcg cgagcagcag cacgatcgcc
    38041 agggtcgcga ggccgagcac gaagagcgtc tcgtggtagc gcgcccacac gtcgttccag
    38101 gtgaagggcg gactcgcgtc gaagggcggc aggcgcagct cgcgcagcat ctcctccacg
    38161 cgggcgtagt cggcggggat ggtgaagccg tggatacggg cggcgcgcgc ggccggatcg
    38221 ccggcctcga ggccgagtgc gagcgcggcc accttgcgca tcagcgccgg gtcggcctgg
    38281 cgcagggcaa cgagcggcca ctcgggatag agccgggtgg agctgtgcag cgggaatccg
    38341 gcgtgctgca gcggatgcag cacgcgcagg ccggagaggt cgcggccctc tgcggacagg
    38401 gcctcgagca ggccggtgcg cacgaagcca gcgtcgaccc ggccgtcgag caccgcgtcg
    38461 acgacgctgt cctggctctg ctgcagcgtg agcatgtcca gcaaggccgg gtcggcgccg
    38521 gcggccttca tctcgaacgc ctgcgccggg taggtggcga ggaagttggc gtgggtcgtg
    38581 ccgacgcgct tgccctgcag gtcggcgagc gcggacaggc gtttgtcccc gctgcgcacc
    38641 aggatcacgc cgccgaactc gttcagtgct tgcccgccgg catcggagac caccgtggcg
    38701 atggcgccgg acagagggtt ggcgctgcgc agcgtaatga aatgcgccgg gttggtcagc
    38761 agcagctcga gctcgccggc ggccagggcg cgctgcagtc cggcatcgtc gagcgcgtgc
    38821 aggcgcacct cgacgccgtc gaggcgcgtg ttcaggtagt cgacgaaggg ttgccacgag
    38881 gcctcgacca gcgccttggg gcgggacgaa tacacgccga aatcgagtcc gggttgggcc
    38941 tgcaggtcca ggctgccgat gcccagacca acgcacagga gggcggtgcg gaggattcgt
    39001 cgcatcagcg ccgggtggcc gtcgaggttg tcgggcgctg cgccggccgg ctcaccgggc
    39061 gagcaaggca gccgcgcgcg ggcgaatcct gggacgggtg ggaaacatca cggcgcatcg
    39121 ggtggagtag ggcagatcaa ctgctcattt tagggctttc gaagcccctg cggcagcccg
    39181 ttcggtcgtc ttgtgacaca gttcgcgcac gcgccggcca gcgcgccccg agctcggggc
    39241 gcgcgccggc ggtgcgacgc tcagtcttcg cgacggcgga agggcttgcc gccgcgttcg
    39301 ccctggcgct tcaccggtgc ggagtggccg ccggccttgc ggtcggtcga cggcgggcgg
    39361 cgctcgtcgt gcgggcggcg ctcgtcgtgg ccgcggaagc ccccgccggg cttgccgcca
    39421 tagccgccac cgggctggcc cgggcgcgga ccgccgaagt cacgcgggcg tcggtcggcg
    39481 tcctgcgacc ggaagccgtc gccgccttcg ggccgcgccg ggcgacggcg ttcgggcacc
    39541 gaggccgcct cggccgcgct cagctcgcgg atcgacaagg gcatctggcg aacgcgggtg
    39601 cgcttgagcg tggcgaggag gtcctcgggc aggttggcgg gcagctcgac cgtggagaat
    39661 tcgtcgaaga ggtggatctg gccgatgaac ttgccctcga tgccgccctc gttggcgatc
    39721 gcgccgacga tctccttggg gctggcgccg tgggcgcggc cgacctcgat gcggtagcgc
    39781 accagcgcgc cttcggagaa ggagcgccgg cgggcgagga tctcgtcgcg gttggggcgc
    39841 ggcgtgcgct cgcgcgcggc gccggtggtg aagtgctcgg cgcgcggcgc gcggccttcg
    39901 ctcggcgtcg tggtggcgat gtcccagccg cggccggact gctcgacctg cagcgggcgc
    39961 tcgcgctggg cgagcagcgc cagcgcagcg gcgacttcgt ggatctcgag ctcgttctcc
    40021 tcgatcaggt cgttgaccac gcccatgaag aagccgagtt cggcgcccgc gatggtctcg
    40081 gcgacctggc gcttgaactg ggccacgcgc aggttggtga cctcctcgct gctcggcagc
    40141 gcgatcgggg tgatcggctg gcgggtggcg cgctcgatca tcttgagcat gcgcgtctcg
    40201 cgcggcgcca cgaacaggat cgccaccccc tcgcgcccgg cgcggccggt gcggccgatg
    40261 cggtgcacat aggcctcggt gtcgtagggg atgtcgtagt tgatcacgtg cgagacgcgc
    40321 ggcacgtcga tgccgcgcgc ggccacgtcg gtggcgatca cgatgtcgag cgcgccgttc
    40381 ttgagctgct cgatcacgcg ctcgcgcagg ccctggttca tgtcgccgtt gagcgcggcg
    40441 gcggcgtagc cgcgcgcggc gagcttgtcg gcgagttcct cggtggcgat cttggtgcgc
    40501 acgaacacga tcgcggcgtc gaagctctcc tcggcgtcga ggatgcgggt gagcgcgtcg
    40561 agcttgtcca ccccgcgcac cagccagtag cgctggctga tcttggccac ggtcgaggtg
    40621 gcggcgcgga tcttgatttc ctgcgggttg cgcaggtggc ggcgggcgac gtcgcggatc
    40681 acgttcggca tggtggccga gaacagcgcg gtctggcgct cggccggggt gtgctcgagg
    40741 atccactcga cgtcgtcgat gaagcccatg cgcagcatct cgtcggcctc gtcgagcacg
    40801 atcgccttga gcgcgtcgag cttgaggctc tcgcgctcga ggtggtccat gacccggccc
    40861 ggggtgccga cgatcacctg ggcgccgcgc gagagctggc gcagctgcac caccatgctc
    40921 tggccgccgt agatcggcag cacgtggaag ttcttcaggt ggtgggcgta cttggcgaag
    40981 gcctcggcga cctggatcgc gagctcgcgc gtgggggtga gcaccagcac ctgcgggcgg
    41041 gtgtcggcga ggtcgagctt ggccagcatc ggcagcgcga aggcggcggt cttgccggtg
    41101 ccggtctgcg cctcgccgag gatgtcgtgg ccggcaagca gttgcgggat gcacgcggcc
    41161 tggatcggcg agggggtctc gtagcccact tcggcaagcg cggagagcag ggctgcgggg
    41221 agctggaggt cggcgaagcg cagttcggct tcggcggggg cggattcggg gcgggaggct
    41281 tcggtcatgg cgtcgtggcc gcgggggcgg cgatgggcag cggcgctgca acatcgcgaa
    41341 ggcgggcgat tgcggcgcgg cgagggtgat ggggcggctc gtggccgcgg cgttgcggcg
    41401 ggtggccgcg gacttgcgcg cctggcgcgt tgcgcgggtg cggaggggcg gcccaaggcc
    41461 gccgcaaatg caaaaacgcg gcgcagggcc gcgtttcggg tcgatcgaga gacgtcgagg
    41521 acgtcggatc gattacagcg ggcggatgtt ggccgcctgc aggcccttcg ggccggtctt
    41581 gacttcgaat tcgacgcgct ggttttcggc caggctcttg aagcccttgc tctggatctc
    41641 cgagaagtgg gcgaacaggt cgtcgccgcc gccttcaggg gtgatgaagc cgaagccctt
    41701 ggcgtcgttg aaccatttca cggtaccggt ttgagtgctc attttgcgtt ccatatggag
    41761 aattgcgggc ttgcgccccg aggtgcagga acgatcaaga aacgtaatca gggaggcatc
    41821 aaaccgacac gcgttttttt ggaacacgct ggcaaccaca ccaacaacca ctgcttgaat
    41881 cgactgcgag ccgcaagata cacgcttttg cgcggatgcg tgaatttatt tttcagttcg
    41941 atcgcatgca gcccatgcgc gggacgcgtg ccggcgtccg gcggtgggat aatccgcccc
    42001 ccgacagtca acgcaggtct ctccatgccc atccagtggt tccccggaca catggcctcg
    42061 gcgcgcaaga aggcggccga ggcgatggcc atgaccgacg tggtcatcga ggtcgtcgat
    42121 gcacgcctgc ccgaggcgag cagcaacccg atgatcgccg agctgcgccg cttccgtaac
    42181 cgcccctgcc tcaagctgct caacaagtcc gaccttgccg accccgaggc cacgcgggcc
    42241 tggatggact tctacaaccg ccagccgggc gtcaaggcgg tggcgatctc ggccaagagc
    42301 ccggccgagg ttgcgcgggt gccggcgctg tgccgccagc tcgcgccgca ccgcgacgac
    42361 ggcaccaagc cgctgcgcat gatgatcatg ggcatcccca acgtcggcaa atcgacgctg
    42421 atgaacgcgc tgctcaagcg caaggtggcc aaggtgggcg acgagccggc ggtgaccaag
    42481 caccagcaga cgctcgacct cggtcccggc atgaccctca ccgacacgcc cggcatgatg
    42541 tggccgaaga tcgaccacga cgccgacggc tacatgctcg cggccagtca tgcgatcggg
    42601 cgcaacgcgg tgatcgacga ggaggtggcg gccttcctcg gcgagatcct gatcgcacgc
    42661 taccccggcc gcctggtggc gcgctatcgg ctggacgccg ccgcggtggc ggcgcttgac
    42721 ggcccggcgc tggtcgaggg ggtgggccgc cggcgcggct gcctggtgaa aggtggcggg
    42781 ctggacctgg agaaggccgc gcagatcctg ctgcaggact atcgcgacgg tgcgctcggg
    42841 cgcatcagcc tggagacgcc gcagacgcgc gcggcgatga tcgccgctgc gcaggcggcc
    42901 gccgctcagg ccgtgagcgc tggcgaggcc gccgggcagg acgcggctgc ggatacggcg
    42961 ggggagggcg acgcgggcgg agatggcggc gactgatccg ccgtctccgg cacgatctcg
    43021 atccagcgca accactgccc gcaggcgttg cgcggcccgc gcagcgagcc gtgccagggg
    43081 ccttcgcgac aggggccgcg cggcgcggcg gggtccagct ccaccgtgct gccgtccgcg
    43141 cccacgcgcc gccacccgcc ccagcgattg caggtggggc agcggcgcag ttccgcgacg
    43201 ggcggggttg tgggcgtggc ggtcatcgtg tttgcgggcg tcggttctcg atcatggtgc
    43261 aggggtgcag cgccgatcgc cctctgcacg agcggtacca tcgcgacgga tggcccggaa
    43321 ggcgtgcgtt cgccacattg ccgccgcgcg ccgcacggcg caggctggat gcgtttgata
    43381 tcattgtcaa tctgtcgttc cccctccgga gtcccatgag cgttccgtca gcctctcggc
    43441 tgcacgccct caacgtcgac ctgcactgcc actccaccgt ctccgacggc tggctcgagc
    43501 ccgaggcgct ggtgctgcgc gcaatctcca acggtgtcga actgctcgcg ctcactgatc
    43561 acgacgaact cggcggcatc gcggccgctc agggcgtcgc ccgcgcgcac gggctggcct
    43621 tcgtccccgg cgtcgagatc tcggtgtcgt tcgccggcga gaccgtccac atcgtgggcc
    43681 tgggcgtcga tcccgagtgc ccggcgctgc gtgcgggcct cgccgctttg cgtgccggac
    43741 gcgacgggcg cgcgcggcgc atgggcgagg agctcgcccg cgtcggcatc cccgacgcct
    43801 tcgccggcgc ctgccgcttc gcgcgcaacc ccgcgctggt gagccgcgcg cacttcgccc
    43861 gccatctggt cgcgagcggg gtgatgcccg acgtgaagac cgtcttcgac cactatctcg
    43921 tgcgcggcaa gcccggcttc gtcgagcacc gctgggcggc gctggaggac gccgtgggct
    43981 ggatccgcgc cgccggcggc atcgccgtgg tcgcccaccc ggcgcgctac cggctgtcct
    44041 cggtcgccct gggcgagctc ttcgaccgct tcgtcgcggc cggtggcgag gccgtcgagg
    44101 tggtggccgg cgcacatacc gaggacgaca tgcgccgctt cgcgagcctc gcgcgccagc
    44161 gcgggctcct ggcctcgcgt gcgtccgatt ttcatggcgt gcaggagagc atggtcgacg
    44221 tcggccgctg caatccgctg cccgccgacc tcgagccggt gtggagccgc ctgccggcca
    44281 ccgccgcggc gctcgcggcg gctgcatcct ccgtgcgcta gggcgcgcgg cccatcgagc
    44341 atccgatcat ggcccagtac ttctccctcc atcccgaaca gccgcaggcg cggctgatcc
    44401 gccaggccgc cgagatcctg cgtggcggcg gcctcgtcgc gctgcccacc gactccgcct
    44461 acgcgctcgc ctgccaggtg ggcgacgccg cgctgctcga ccgcatccgc cgcatccgcg
    44521 gggtggacga gcgccaccac ttcaccctga tgtgccgcga cctctccgag atcggtacct
    44581 atgcgcgggt ggacaacagc cagtaccggc tgctgagggc ggtcaccccc ggcccctaca
    44641 cgttcatcct cgaaggcacc aaggagctgc cgcgccgcgt gctccatccc aagcgcaaga
    44701 ccatcggcct gcgcgtgccc gagcacgcgg tggtgtcggc cctgctcgcc gagatcgacg
    44761 gcccgctgct gacctccact ctgatcctgc ccggcgatga gctcccgctc accgaccccg
    44821 aggagatccg cgaccgcctc ggcaagctgg tggagctggt catcgaggcg ggctattgcg
    44881 gcccggaggc gaccacggtg atcgacctga cctcgggcgc gcccgagctg gtgcgcgccg
    44941 ggcgcggccc gctcgagccc ttcggcctgt agaatgcgga gtttgccacc gagcccgcga
    45001 tggattcgct gatctccacc ctggccatct gggccctccc ggtcgtgctc gcgatcacgc
    45061 tgcacgaggc cgcgcacggc tacgtggcgc gccacttcgg cgaccccacc gcccacctcg
    45121 ccgggcgcat cacgctcaac ccgctgcgcc acatcgaccc ggtgggcacc atcctggtgc
    45181 cggccggcat cctcgcgctg agctcgctcg ccggcgcggg cggcatcctg ttcggctggg
    45241 ccaagccggt gccggtcaac ttctcgcgcc tgcgcaaccc caaggccgac atgctgtggg
    45301 tggcggcggc cgggcccttc gtcaacttcg tcatggcgat cggctgggcg gtgctgttcc
    45361 gcgtcgccgc caccgccgag ccgggcgcct acacgctgcc catgctcaag atggccgacg
    45421 ccggcatcca gatcaacgcc gtgctgatgg cgctcaacct gctgccgatc ccgccgctcg
    45481 acggcggccg catcgcggtg agcctgctgc ccaaccggct cgcctggcag tacgcccgcc
    45541 tcgaacccta tggcttcccg atcctgctcg tgctgctgtt caccggcgtg ctcggcaccc
    45601 tgctgtggcc gctgatcgcc ggcttccgct acctgctctc cctcgtcttc ggattctgat
    45661 cctccatgta cgctgaacgc gtcctctccg gcatgcgccc cagtggccgg ctccacctcg
    45721 gccactacca cggcgtgctc aagaactggg tgaagctgca ggaggagttc ccctgcctgt
    45781 tcttcgtcgc cgactggcat gcgctcacca cgcactacga cacccccgag gtgatcgagg
    45841 ccaacgtctg ggacatgctg gtcgactggc tcgccgccgg ggtcgacccc gcgcagtcca
    45901 cgctcttcat ccagtcgcag gtgcccgagc acgccgaact gcacctgctg ctgtcgatga
    45961 tgaccccgct cggctggctc gagcgcgtac cgacctggaa ggagcagcag gagaagatcg
    46021 agggccgcga cctgtcgacc tacggcttcc tcggctaccc gctgctgcag tcggccgaca
    46081 tcctgatcta ccgcgccgac aaggtgccgg tgggcgagga ccaggtcccg cacgtcgaga
    46141 tcacgcgcga gatcgcgcgc cgcttcaacc acctctacgg ccgcgagccg ggcttcgagg
    46201 acaaggcgaa ggacgcggtg cgcaagctcg gcgccaggcg tgcgcgcatg taccacgagc
    46261 tgcgcacgcg cttccagcag gagggcgacg acgacgcgct cgagcaggcc aaggcgctgc
    46321 tcgacgagac ccagaacctc tcgctcggtg atcgcgagcg cctgtacggc tatctcgagg
    46381 gcagcggcaa gatgatcctg gtcgagcccg aggcgctgct cactccggct gcgcgcatgc
    46441 ccggcctgga cggacagaag atgtccaagt cctacggcaa caccatcaac ctgcgcgagg
    46501 acgccgagag cgtcacgcgc aaggtgcgca ccatgcagac cgaccccgcg cgcatgcgcc
    46561 ggaccgaccc gggcgagccc gagcgctgcc cggtgtggca gctgcatgcg atctactcgg
    46621 gcgaggagac ccttgcctgg gtgcagcagg gctgccgcag cgcgggcatc ggctgcctgg
    46681 agtgcaagca gccggtgctg gaggcgatcc tgcgcgagca ggaggtgctg aacgagcgcg
    46741 cccagcccta tctcgacgac ccctcgctgc tgcgcagcat catcgccgat ggctgcgagc
    46801 gcgcgcgccg gctcgcgcag gagacgatgc gcgacgtgcg tgaggcgatg ggcctcgact
    46861 acggttgagc cacccgcacg ccgcctcacc gatcgcagcc gcaccatgaa cctgccgctg
    46921 gacctggcgc cggtcgacac cggcgcgccg ctcgatgtgc tcgcgcgcat ctacggcgag
    46981 cccctgctcg aactgcccaa agacctgtat attccgcccg acgcgctgca ggttttcctg
    47041 gaagccttcg aggggccgct ggatctgttg ttgtatctga tccgcaaggc caacctcgac
    47101 atcctcgacg tgccgatggc gccgctcacc gcgcaatacc tcgagtacgt cgaggcgatg
    47161 cgggcgacca acctcgagct cgccgccgaa tacttgctga tggcggcgat gctgctcgaa
    47221 atcaagtcgc gcatgctgct gccgcggccg ccgcgcgaga acgcggaaga agaggacccg
    47281 cgcgccgagc tggtgcgccg gctgctcgaa tacgaacaga tgaagctcgc cgcggcgcgg
    47341 ctcgaggctc tgccgagggt ggagcgcgac ttcgagtggg tgggcgtctt cgtcgccgag
    47401 aaggtggtcg agcgcctgcc cgaggtcagc ctgcacgacc tgcagctcgc ctggctgcgc
    47461 atcatgaaga aggcgcggct caatcagagc caccgcgtcg gccgcgagca gctttcggtg
    47521 cgcgagcaca tgacggcgat cctgcgcagg ctcggcgacg gcgccttcgt cgttttcgac
    47581 accttgttcg acgtcgagct cggcccgccc ggcctggtgg tgagctttct cgccgtgctc
    47641 gagctggtga aggaaagact ggtcgatgtg acccagaacg aggcctttgc gccgatctac
    47701 gtgaagctcg cagatgcaac ccgcaacgac gcctgagacc tggctacgca tcgtcgaggc
    47761 ggcgctgctc gccgcgccgg gtccgctgcc ggtgtcggag ctgcgcaagc tcttcgacga
    47821 ggatccgggg ccggacctgg tgcgccgcct gctcgacgag ctgcgcacgc agtggttcga
    47881 ggccgcgcgc ggggtcgagc tggtgcagct ggcgagtggc tggcgcttcc agacgcggcc
    47941 cgagtaccag gtctacctcg accgcctgaa ggaagaaaag ccgccgcgct actcgcgcgc
    48001 ggtcatggaa acgctggcga tcatcgccta tcgccagccc gtcacgcgtg gagacatcga
    48061 ggacatccgc ggcgtggcgg tctcgcccaa cgtcctgaaa accctcgaat cacgcggctg
    48121 ggtcgacatc gtcggccacc gcgacacccc cgggcggccg gcgctgttcg ccaccacccg
    48181 gcgcttcctc gacgagatgg ggctgcgcag cctgaccgag ctgcctgcgc tcaccgaact
    48241 cgaaaaaatc atggatctag tcgatgtctc gcaaaccgaa ccggccgctg cgcccgcccc
    48301 tgaagaagaa gtctgacgcg atcgagatcc tcgaccgcga cccgcgcgaa tcccgtggcg
    48361 gcaggcgcgg cgagggggcg ccgcgcgacg aggacgccca gcccagccgc aaggacgccc
    48421 acctcaacgt cgacccgcgc ggcccgcgca cgccgcgtcc gccgcgagcg ggcggcgcgc
    48481 cggcgccgcg ccgcccgcgc atcgagggcg accccgcgcg ccaccccgag gcccaccgct
    48541 ccgccctcgg ccagcccgag gccggcgagc gcccggcgcg tggccggggg cagggcgggg
    48601 ggcgtaacgc ccccaccacg ctcaccgagc ccgagcgcct gcagaaggtg ctcgcccagg
    48661 ccggcgtcgc ctcccggcgc gagatcgagg agtgggtggt ggccgggcgc atctcggtca
    48721 acggcctgcc ggcctcgctc gggcagaaga tcgggccggg cgatcgcgtc aaggtcaatg
    48781 gcaagctcgt cccgctgcgc ttcacccagc gctcgccgcg cgtgctgatc taccacaagc
    48841 ccgagggcga gatcgtctcg cgcgacgacc ccgagggccg gcccaccgtg ttcgagcgcc
    48901 tgcccatcct gcgcaagggg cgctggctgg cggtcgggcg cctggacttc aacacctccg
    48961 ggctgctcct gtttaccaac gacggcgacc tcgccaacaa gctgatgcac ccgcgctacg
    49021 agctcgagcg cgagtacgcg gtgcgcatcc tcggcgagct gaccgaggag caggtcaagt
    49081 cgctcaccga aggcatccag ctcgaggacg gcccggcgaa gttcaacctg ctgcgcgacg
    49141 agggtggcga aggcgccaac cactggtacc gtgtgaccat ctcggagggc cgcaaccgcg
    49201 aggtgcggcg catgttcgag gccgtcggcc tgaccgtgag ccggctgatg cgggtgcgct
    49261 acggcagcgt cgagctgcct gcccggctca agcgcggcat gtggatggag atgcccgagg
    49321 ccgaggcctg cgcgctcgcg ggcctgccgc cgccgcagca gagccgccag caggaccagc
    49381 gcgacaagcg cccggtcaag ctgcaccgta cccagccgcg ctgagcgccc ccgccctcga
    49441 cggggtgtct cgcgggggag ccgcccacgc gcgatctgcg cgcgtgggtt tgctcgaccc
    49501 cgcgttttgg ctgtatactc gttcggcttt gatggatgga tttcctttgt ggtcacgagc
    49561 cacggcaggc gtccgctccg tcatgcggtt gtggccagcg ggttttcgtg caggaacaat
    49621 tgtttgatgg gcgtttcgcc cattttttat ttgtggtgcc cgatgtggcg ccggagcggt
    49681 ggggcaggca gatgcgagcg gacgtcgagg ggttgatcga gcaggtggtg accggactgg
    49741 gatacgaact cgtggatgtc gagttctcgc ccaagggccg cttgctgcgc gtcttcctcg
    49801 acatcgagcg cggcatcacg gtcgacgatt gcgccaccgt aagcaaccag ctgcagcgcg
    49861 tgttcgaggt cgagaacgtc gactacgacc ggctcgaggt gtcctcgccc ggcctcgatc
    49921 gcccgctcaa gaagctggcc gacttcgaac gctttgccgg cgagcaggcg caggtccgcc
    49981 tttcgctgcc gatcggcaat caacgcaatt tcgtgggtgt gatcgagcgg gtgcaggacg
    50041 gcgcggtggc gctgcgcacc gagaagggcg aagtgctgct gcccttcgac gacatcgaga
    50101 aagcacgcct ggtgccccaa ttttgagact gtggatgtgg aggttttact gaaatgagcc
    50161 gcgagatcct gctgcttgtc gatgccttgg cgcgtgagaa gaacgtcgcc aaggagatcg
    50221 ttttttccgc gctcgaaacc gccttggcct ctgcgaccaa gaaacgcatc cacgacgatg
    50281 ccgacgtggt ggtgtcgatc gatcgcgatt cgggtgatta cacctcgaag cgccgctggc
    50341 tggtaatgct cgacgaggag gtcgtgaacg acgaggccga gatgggcatc atcgacgccc
    50401 gcgagctgcg cgccgacgtg cagatcggcg actacatcga ggaagagctc gagccgatcg
    50461 acttcggccg catcggcgcc caggccgcca agcaggtcat cctgcagagg atccgcgacg
    50521 ccgagcgcga gcaggtgctc aacgacttcc tcgaccgcaa ggaattcctc gtctccggct
    50581 cgatcaagcg catggagcgc ggcaacgcga tcatcgaggt cggccgcatg gaggccgtgc
    50641 tgccgcgcga ccagcagatc ccgcgcgaga acctgcgcgt gggcgaccgc gtcaaggcct
    50701 tcctgctgcg catcgaccgc ggcgcccgcg gcccgcagct cgtgctgtcg cgcaccgcgc
    50761 ccgagttcct catgaagctc ttcgagctcg aggtccccga gatcgaggac gggctgctcg
    50821 agctcaaggc ctgcgcccgc gaccccggcc tgcgcgccaa gatcgcggtc aagtccaacg
    50881 atcagcgcat cgacccgatc ggtacctgcg tgggcctgcg tggctcgcgc gtcaccgcgg
    50941 tgcgaaacga gatcggcggc gagcagatcg acatcatcgt gtggtcgccg gaccccgccc
    51001 agttcgtggt cgccgcgctg cagccggccg aggtcgtctc catcgtcgtc gacgaggagt
    51061 cgcacgccat ggacgtggtg gtcgacgaga acaacctcgc gatcgccatc ggtcgcagcg
    51121 gccagaacgt caagctcgcc tccgagctca ccgggtggac gatcaacctg atgagcgagc
    51181 aggagtcggc cgagaagacc gcccaggagc aacagggcct gcgcgcgctg ttcatggaaa
    51241 agctggacgt cgacgaggaa gtcgccgaca tcctgatcga ggagggtttc tcctcgctgg
    51301 aagaggtggc ctacgtgccg ctctccgaaa tgctcgagat cgaggccttc gacgaggaca
    51361 cggtcaacga gctgcgcaat cgagcgcgca atgtgctgct gaccgaggcc atcgtcaccg
    51421 aggagcagct cgagaaggtt tccgacgact tgctcggcct cgaaggcatg gagaagtcgc
    51481 tggccgccac actggcccag cagggcattc gtacccgcga cgacctggcc gaccttgcgg
    51541 tcgacgagct ggtcgaaatg gccgggatcg acgaagaaag agccaaggcg ctgatttccg
    51601 ttgcgcgcgc ccattggttc gaagaatgat gggagggcag taatggaaca gatgagcgtg
    51661 acccagtttg ccggcgaact gaaaatgccg gccgcggtgc tgctcgagca gttgaagcgt
    51721 gcgggcgtgg aaaaatccgg ccccaccgac ctgctcaccg aacaggacaa ggcgaggctg
    51781 ctggaatacc tgcggcgttc gcacggcgat acccagccca agggcaagat caccctgacg
    51841 cgcaagcaga cgaccgagat ccgcgccacc gactccaccg ggcgtgcgcg cacggtgcag
    51901 gtcgaggtgc gcaagaagcg caccttcgtc aagcgcgacg agctcgccga gcaggccggg
    51961 gtcgaggccg cggcggtcga gccggccgag cttgccgagg cggtgatgga agcgccggtt
    52021 gcggttgaag ccgtcgcgcg ggcggttgaa gccgtcgcgc ccgtcgccga agccgccgcc
    52081 gtcgaagtgg cgccggccgt cgaggctgcg gcgccggcgg cgatcgagtc gtccgagccg
    52141 gtcgccgtcg tgtcggtcgc cgaggtcgaa gcgccgaccc ccgcgccggt cgccgaggtc
    52201 gaggcgccgg caccggtcgc tgccccggcc cctgcagccg cacccgccgc ggccgcatcc
    52261 acggccgctc gtcctgctca gcagggcggc cgccagggcc gtggcgagcg ccagtcccgt
    52321 caggagcccg cgccgcagcc ccaggtcacc accgtgctga gcaagccgct gccgctctcc
    52381 gagattctca gcgaggaaga gatcgctgcg cgcaagcgcg acgaggatcg ccagcgcgcc
    52441 ctcaaggagc gccaggcggc tgacctgcgc gcccgccagg agcgcgaggc tgctgccaag
    52501 gcggcagccg aggcgcgcaa ggccgaggag gaagcccgcc tgcgtgccga gcagcagaag
    52561 aaggaagagc ccgccaaggc agcggccaag ccgaccaccg gcaccctgca tcgccccgcc
    52621 aagaccgagg acaagcccg
//
LOCUS       DAOTIN010000012        51670 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_663_length_51670_cov_9.009978, whole genome shotgun sequence.
ACCESSION   DAOTIN010000012 DAOTIN010000000
VERSION     DAOTIN010000012.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 51670)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 51670)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51670
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_663_length_51670_cov_9.009978"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(149..937)
                     /locus_tag="P5537_03345"
     CDS             complement(149..937)
                     /locus_tag="P5537_03345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein phosphatase 2C domain-containing
                     protein"
                     /protein_id="HRV77110.1"
                     /translation="MPFTAETCVAMHLGDRKEQQDRVALFGHPKRPGMMMAVLADGMG
                     GHSGGAMAAEQVLMRARQNFEAYAPLHETPEHLLRSIIDEAHVVIKLTRFTSEQDPHS
                     TAVVFMMQQGKAYWAHCGDSRMYHFRGTRTMSVSGDHSLVAELVRKGRLDDRSALRHP
                     QRNVLLSCLGSDREPRIDYGREESPLGGDAFLLCSDGLWAHFTEFELASTLQEFPARA
                     AAERLVALGRERAGGTGDNISLAVVKLVEARTDAATPTRPAIAR"
     gene            complement(1063..2304)
                     /gene="glcF"
                     /locus_tag="P5537_03350"
     CDS             complement(1063..2304)
                     /gene="glcF"
                     /locus_tag="P5537_03350"
                     /EC_number="1.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate oxidase subunit GlcF"
                     /protein_id="HRV77111.1"
                     /translation="MQTQLADFIRDTPEGREAEEILRKCVHCGFCTATCPTYQLLGDE
                     LDGPRGRIYLIKQVLEGAEPTEKTRLHLDRCLTCRSCESTCPSGVHYSRLLDIGRAVV
                     AERVPRHGGEALMRRTLREFVPRPRLFGLAMGAGRAVRGLLPKSLQDKVPTLRPAGAW
                     PAPRHARRVIALAGCAQPAMAPSINAAAARVLDALGISMVELPGAGCCGAVRFHLDDA
                     EGARADARRNIDVWWPDIEAGRIEAIVMTASGCGVQVRDYGHLLQHDPAYAERARRVA
                     ELTRDIAELVLAEGEALRARLAARAQPREPLAWHAPCTLQHGQRIRGTVESLLTAAGY
                     ELTPVRDAHLCCGSAGTYSILQPELSGRLRANKLDALLEGGAGRIASANIGCITHLQA
                     GTDKPVLHWIELIDARLGTAS"
     gene            complement(2308..3378)
                     /gene="glcE"
                     /locus_tag="P5537_03355"
     CDS             complement(2308..3378)
                     /gene="glcE"
                     /locus_tag="P5537_03355"
                     /EC_number="1.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate oxidase subunit GlcE"
                     /protein_id="HRV77112.1"
                     /translation="MTTIEKEWAERVRAAAAARTPLCLRAGGSKDFYGGPLAGEPFDL
                     RANHGVVAYEPTELVVTVRGATPLAELEAVLADRGQYLAFEPPHFGPGATVGGCVGAG
                     LSGPRRANAGAVRDFMLGVKLLDGRGEVLRFGGQVMKNVAGYDISRLVTGSLGTLGIL
                     LEVSLKVLPRPVAEATLRFELDEASALRRVNEWGGQPLPVSATLWQDGVLHLRLSGAE
                     AAVQAACARLGGEALAPGAAQALWTAVREQTLPGFAVEEGSVLWRLSVPSTAPALGLP
                     GRQLVEWGGAQRWLAGAADAQAVRARAVELGGHATAFRAGDRAAGVFQPLAAPLAVVH
                     RRLKQAFDPAGIFNPGRLYPEF"
     gene            complement(3618..5129)
                     /locus_tag="P5537_03360"
     CDS             complement(3618..5129)
                     /locus_tag="P5537_03360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-linked oxidase C-terminal domain-containing
                     protein"
                     /protein_id="HRV77113.1"
                     /translation="MMLENEVLAFGETEGDFSAVDKARVIEALSRVLPAGTLMYDAED
                     LRPYECDGLAAYRALPLVVALPSTEEQVVAVLRICHQMGVPVVARGAGTGLSGGALPH
                     TRGVLLSLARFNRIVALDPLARTAVVQPGVRNLAISEAAAPYGLYYAPDPSSQIACSI
                     GGNVSENAGGVHCLKYGLTVHNLLRVRGVTIEGEIVEIGSGALDSPGYDLLALVTGSE
                     GMLVVLTEVTVKLVPKPQLAQCVLATFDDVVRAGDAVAKIIAAGIIPAGLEMMDQPAT
                     AAVEEFVRAGYPLDAKAILLCEADGTPEEVAEEVDRVRAVLQESGASEIRVSRDEAER
                     LRFWAGRKAAFPAAGRISPDYYCMDGTIPRKRIGEILTAIQAMEGKYGLRCMNVFHAG
                     DGNLHPLILFDANQPDELERAEAFGAEILELSVALGGTITGEHGVGLEKINQMCAQFT
                     TAEVRQFFRVKAAFDPPGLLNPGKAIPTLNRCAEYGRMKVSKGHVPYPDIPRF"
     gene            complement(5307..6188)
                     /locus_tag="P5537_03365"
     CDS             complement(5307..6188)
                     /locus_tag="P5537_03365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HRV77114.1"
                     /translation="MAQRRIPPIQCLLTFEAVARLRSASRAAEELCVTVSAVSHRLRQ
                     LESHLGVRLFSRSDFTPTAEGAAYLQQVGVALAALRELPGERAPAVAPRLRVAVTPSF
                     CRQFVMPKLELFRRDWPEIELTLQVSIPLRDVVAEEADLEIRYGAGGYTDLEHRLLLC
                     DDVVPACSPAFLAEHGPFDGFASVAECSATALVRSPLEPWSNWFAHCGLTLPEPARGA
                     QFNDLGLAYDAAASGFGVALVRQRLGAAWFDGGRLLALSSRPLRSPHAHYLCWRPGAL
                     ERWECAAFADWLQAVLP"
     gene            6470..8164
                     /locus_tag="P5537_03370"
     CDS             6470..8164
                     /locus_tag="P5537_03370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004380838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HRV77115.1"
                     /translation="MSRPHRLLPFLAWPAQWREHGLRGDLVAGVTVALVLIPQALAYA
                     KLAGLPPHIGLYAALVPAVVAALFGSCGQLSTGPVALTSLLVGASILPLAGSPGDDLV
                     GLALLLALLSGLFQLALGVLRLGWLLNLLSVPVLMGFVNAAALIICLTQIPPLLGLAM
                     PHSDHLLVDFVRALGGLDALQPAAVAFGVGSLVALIALKRLWPRLPGVPLVVAATIAI
                     SAWTGFAAQGGAVVGEVPAGLPGFSLPPLRPELIATLLPAAFVVAMVSFMEAASSAKL
                     ISGRTRQPWDQDQELVGQGLGKLAAAFTGGLPVSASFSRSALNYVNEARTGLSSLVTA
                     AFVLVTLLWFTPLLWHLPKPVLAAIILQAVAGLIDTGVMLRAWRASRDDGAAAAVTFL
                     ATLAFAPNIQNGVFTGLILSLALLVYRGMRPRVALLGLHEDGTYRDRERFDLPHPHAQ
                     LVILRFDSPLSFVTAATFEDAMLGAARAQDGVKIVLVSAAGINAIDATGLHTLASLVE
                     RFHVQGQTIAFCGLKKQVIDAMERDGLWSRIGKQSSYRTEHQALDALLPTLAAPAG"
     gene            8585..8896
                     /gene="rplU"
                     /locus_tag="P5537_03375"
     CDS             8585..8896
                     /gene="rplU"
                     /locus_tag="P5537_03375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011766892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HRV77116.1"
                     /translation="MYAVIKTGGKQYRVAAGEKIKVEQIPADVGSEITIDQVFMVGEG
                     DAVKIGTPVVAGASVKATVVSHGRHDKIKIFKMRRRKHYQKHQGHRQNYTELRIEAIS
                     A"
     gene            8917..9180
                     /gene="rpmA"
                     /locus_tag="P5537_03380"
     CDS             8917..9180
                     /gene="rpmA"
                     /locus_tag="P5537_03380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011236299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HRV77117.1"
                     /translation="MAHKKAGGSSRNGRDSESKRLGVKRYGGQFVLAGNIIVRQRGTE
                     YHPGDNVGIGKDHTLFALTNGVVQFAVKGPSRRRTVIIVPEAA"
     gene            9288..10481
                     /gene="obgE"
                     /locus_tag="P5537_03385"
     CDS             9288..10481
                     /gene="obgE"
                     /locus_tag="P5537_03385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HRV77118.1"
                     /translation="MKFFDEARIEVYAGDGGNGAATFRREKYIPKGGPSGGDGGRGGS
                     VYAVADRNLNTLIDYRYTRSFRAERGENGGSRDCYGKGGDDITLRFPVGTVIKDQETG
                     ELVADLDVDGKTVLIAQGGRGGLGNIHFKSSTNRAPRKKTMGKEGEYRNLHLELKVLA
                     DVGLLGMPNAGKSTFIRSVSAAKPKVADYPFTTLAPNLGVVRTSEARSFVIADIPGLI
                     EGAAEGAGLGHQFLRHLQRTHLLLHLVDLAPFDPEADPVADAKAIAEELRKYDEDLYA
                     KPRWLVLNKLDLIPEEERAERVAAFLEAYGPVERHFQISAMKGEGTQALIFAIQDLLD
                     AERDRIEAERAEREAAEAARLAAADAERAAADAAYEREALLDADDELPEDEPDAEEDD
                     APPPR"
     gene            10566..11693
                     /gene="proB"
                     /locus_tag="P5537_03390"
     CDS             10566..11693
                     /gene="proB"
                     /locus_tag="P5537_03390"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HRV77119.1"
                     /translation="MRTKLRNARRLVVKVGSALVTNNGAGLDKDALDAWARQIAALRA
                     EGREVALVSSGAIAAGMQRLGWTKRPTEMSKLQAAAAVGQMGLVEAYEKAFSRHGLHT
                     AQILLTHEDLADRNRYLNARSTLTTLLALGVVPIINENDTVVTDEIKFGDNDTLGALV
                     ANLIEAEALIILTDQQGLYTADPRKDPAATLIGEGRAEDRQYEAMAGGSGSAISKGGM
                     ITKIRAAQRAARSGAHTCIASGREPDPILRLAAGEALGTLLYASSTPLQARKQWLADH
                     LQLAGDLVIDDGAVAALKSGKSLLPVGVVEVRGDFERGAVVACRNIAGEEVARGLVNY
                     SASECRRIARRPTAEIGNLLGYVDEPEVVHRDNMVSHNVRS"
     gene            complement(11752..12029)
                     /locus_tag="P5537_03395"
                     /pseudo
     CDS             complement(11752..12029)
                     /locus_tag="P5537_03395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013104216.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            12339..13418
                     /locus_tag="P5537_03400"
     CDS             12339..13418
                     /locus_tag="P5537_03400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011766896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77120.1"
                     /translation="MRKCKKCLLPEAAPGADLDSSGVCAACRATPTRRTTQPDASRYR
                     EDLEASLEAARNHAGSSYDCIVPLSGGKDSLFLLHRLKVEYGMRVLAFTCDIDLPPIA
                     WANIRLALRKLDIDHLVFTPAHAFLTKLFRYLLKNQEARGAVYSVSYVYAPLFEGAAI
                     RLAIEKNIPLVLAGYSPGQPEPERMLYEFAPALVSGEDWTPPHLKECGEFSADELEAF
                     YNPLRLPAGTRFPRYIAPYHAWEYDQDQVVRKVTELGLVRRSTHASPIVSNYPINWLM
                     MYSDLHNFGYNPYAPEFAALIREGRASLRYWRVMAPIVDLMIRHKIGLGREVRRSMKW
                     LGLDDADLRITLPRGAYDPPMLRGG"
     gene            13424..15202
                     /locus_tag="P5537_03405"
     CDS             13424..15202
                     /locus_tag="P5537_03405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004334385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HRV77121.1"
                     /translation="MDDAPLSLLDRLRSRALETPQHIAYLYRHPGSSERWDTLSWGQV
                     LARVEAMSAALADLGLRDGDRAAIMMPTSPDWEICQFAAMAVGCAVIGLDLHDAPRNL
                     RHILEATRPRIIFTTDPGQLERIAECWHAPELAVISSGEAKTSGTHLLATLLATASAL
                     EKSRSPQPDQVATIVFTSGSTGQPKGIAYTHRQIISASDLILERFPDIRSDARLVCWL
                     PLSNLFQRMVNFCAMRRGAASYFIADPHTIASVLPQTEPTFFIGVPRFFEKLHAGIVR
                     EIESKPLPLRVLLETSWAIGMRAARARRERRSADMLTRALLPLADRVLARIRAVMGRN
                     LQFMVSGSAPLPVWLAERLHGLGWLVLEAYGISENVAPIAMNTPDDFRFGSVGHVLPG
                     NELRIADDGELLVRGPCVFGGYYEGTDEGSPIDAEGFLHTGDYARIDDAGYLWLEGRK
                     SDVFKTSTGRRIAPAPIEGALRSIPGVEHAVVIGHDRPYPVAILALAAHSLQGAGGER
                     AVLERIAADVVATCGIFPPYQRPGALIVTFRPFSIETGELTANLKIRRRPVELGFRTQ
                     IDEAYSRPASRTERGATTALPVITSS"
     gene            15199..16338
                     /locus_tag="P5537_03410"
     CDS             15199..16338
                     /locus_tag="P5537_03410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011766898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HRV77122.1"
                     /translation="MSTYFLTGASGAVGSAIVPLLLVDPATKLRILLRARTPAHLEER
                     FQSLCEFWRIAPENADRRRIEPLRGDAALPQFGLSAVDYARVCEDTTHVIHCAASVRM
                     NETLDEARASAIGSAREVLTLARALQARSLLRKVEFVSTVGIAGKRQGALPERWIDEA
                     REFHNSYEQSKAEAEQLVRHAIDTEGLPVTVHRPSMVIGDSRDGRIIHFQIFYFIAEF
                     MSGRKTFGLYPDFGEVRLDVIPVDWVARAIVDASRSPETAGSIFHLCSGPQRSPRLNE
                     LRPILRQAFRDHGHRLPPCFTVPHRLFAALPRIGALVAPPRMRRALSTLPIYLDYLAD
                     NQGFDNRVFVARLAERSLRLPDWGEYLPVVLSYYLKAKYGPRQSP"
     gene            complement(16373..17584)
                     /locus_tag="P5537_03415"
     CDS             complement(16373..17584)
                     /locus_tag="P5537_03415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011288130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV77123.1"
                     /translation="MFRLAFRNIVRQRLRTAMTLAAIVFGVMALILSGGFVHDVYHQL
                     GEALIHSQSGHIQVAKEGFQERGARSPERYVIEDSEGLRGLLAARPGVEDVMARVNFS
                     GLINNGRSDWAIVGQGVEADKEAVLGSQLKITAGRQLGAADRYGVLLGQGVAQALKLE
                     PGDYVTLLANTLDGALNSLELEVVGVFQSFSADFDLRAVSISLEAAQELLGTAGVNTF
                     VISLRETPLTESTAEALRSGLAGSGFAVLTWRTLNSFYENTVALYERQFGFLQLIILV
                     LVLLGVANSVNMSAFERVGEFGTMMALGNRRGDIRRLVIVENVLLGMIGGGLGVALGG
                     VSALVLSAIGIEMPPPPNANLGYTAHIRLVPSVLASSFSVGLVATVLASLLPAWRVAR
                     IQPVDALRRNA"
     gene            complement(17599..18846)
                     /locus_tag="P5537_03420"
     CDS             complement(17599..18846)
                     /locus_tag="P5537_03420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HRV77124.1"
                     /translation="MRLPGAFAYLIQEYRAAARNVTRQYRRSLFGVIAVAFGVVALVL
                     ATGFVEWIFWATREGTIQNGLGHVHVVRDGYLEHGQADPFEFLVDDGPAELGRLAAVP
                     GLKVIAPRLAFNGMISHGEHTLSFLGEGVDPEAERVLSRAMIVAEGSVLSGASDEGIL
                     LGRGLAENLGVRVGDRVVLLANTAAGGLNAVEAVVAGLFTTVSKAYDDSAARMPLALA
                     QRLLRTEDVHRLILVLDDTARTPAVLESLRAGHSGSGLVFVPWYEMADFYSKLVSLLS
                     RQMGVVQTIIGIIIVLSISNIMMMNVFERTAEIGTCMAIGRTRRQILRQFLFEGLTIG
                     LTGAAMGAILGVVGGFAISWVGIPMPPPPGMSESYRGEILVTVSLLVQALGLALVTTL
                     AASAYPAWKASRLEIVDALRHNR"
     gene            19217..20119
                     /locus_tag="P5537_03425"
     CDS             19217..20119
                     /locus_tag="P5537_03425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-CTERM sorting domain-containing protein"
                     /protein_id="HRV77125.1"
                     /translation="MKLKTLAAAVLLAGMATGAAQAAPWVGNFNTSNGATFNDGLLLN
                     IDGFDIYSQGSAAFFVGGTQLSPTGSTLAVGDIVTTYYQGVVSAFNTGVSSPNLAWAS
                     QPGGSYQLTVAAVFNEIVTFATPGFALVQPISGGRVSVFYDDATLSNSFITSTAQVLA
                     GTGYTDGLLIADGSVSGASLPTSFSTNGTEAGGVANLKGPLTLAQAGWDDPANLADVV
                     GFLPTVPSDYSSRTTLQFGPNEGTSFQTKNFFDAANGWTPVASIAGRTIRADANVNLI
                     PEPATLALLGLGLFGAGLARRRKA"
     gene            20189..20860
                     /locus_tag="P5537_03430"
     CDS             20189..20860
                     /locus_tag="P5537_03430"
                     /inference="COORDINATES: protein motif:HMM:NF012360.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77126.1"
                     /translation="MKTDARDFLLSTLLIGLNLAASAFALSLCWPLVTTLAGSFAQVV
                     GALLAPATYGLCTAASLALLGRFHPLREGEYDLAHEQFTQWKVRHVVAELGKLALSLY
                     FPVFARAAFYALFGTRVGRQVAVAGKILDPGLTVLEEGCVLGEGCIVTSHTMWGERFV
                     MREVHVGANATVGVGCILMPGVRVGSRAVLLPGSVVKTGTVIGSGEIWGGVPASRLKG
                     PGDHA"
     gene            complement(20876..21376)
                     /locus_tag="P5537_03435"
     CDS             complement(20876..21376)
                     /locus_tag="P5537_03435"
                     /inference="COORDINATES: protein motif:HMM:NF022072.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SRPBCC domain-containing protein"
                     /protein_id="HRV77127.1"
                     /translation="MLAGNASPRVFREGFFCLRLETEVFVDAPVESVWEILVRVDRYA
                     EWNPALPEAAGEAVVGGELLVLIEWPGLKRDRYRLRVTEVEAGKSFAWLGHFGVRGLM
                     DGLHRFELEPRASGGVVVRQRETFSGLLVPLFAPWLRDNVLRGFVQVNEALRERVESE
                     RRAAAS"
     gene            complement(21391..22998)
                     /locus_tag="P5537_03440"
     CDS             complement(21391..22998)
                     /locus_tag="P5537_03440"
                     /inference="COORDINATES: protein motif:HMM:NF012935.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMC family oxidoreductase"
                     /protein_id="HRV77128.1"
                     /translation="MDDLAAVTDRVWDCVVVGTGVGGATLGHALAAAGQRVLFVEKGR
                     AGLEPSDGLRGFYPETHFEEAALAAPRHQALLRQGGRWSEEVLSGGGGFVPLLGCGGG
                     GSSALFGMAMERFFPEDFRPGPRLHALAGGSSLPDAWPVSYEEMLPFYRRAERLYRVR
                     GARDPLRPADEALPAAPVPGPHNAELARHFAAAGLHPYRLPLACEFVNDCACCQGFLC
                     ARDCKNDAARSCLRPAVREHGAVLLDECEAITLEAAGDRITALVCRRHGTEFRVRARH
                     YALGAGALATPCLLLSSRSPGWPDGLANRSGLVGRNLMRHGVDLYLVFTRARGDPRSK
                     EIGLSDFYVGAGEKLGTLQSFGALPPASMLATEVIADASAALPFAGVVAKAMRPLLER
                     GLAALFRRGVLLAGIMEDLPYPDNRIEAGDPPRVHYVLREPDRARLRLFRQGIARALK
                     PYRFLPLRQAEKNRMLAHVCGTCRFGDDPASSVLDRNNRAHGVANLYVVDASFFPSSG
                     GTNPALTIAANALRVAEHMLTRNHAEV"
     gene            complement(22991..24229)
                     /locus_tag="P5537_03445"
     CDS             complement(22991..24229)
                     /locus_tag="P5537_03445"
                     /inference="COORDINATES: protein motif:HMM:NF012427.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HRV77129.1"
                     /translation="MIAVTDVARERRRPRVLFVADAVTLAHLARPVALARAIDPERFE
                     VHLAADPRFARFLGPLSCALHELETMPSDRFLDNVARGRPLYDAATLRAYVAADLALL
                     EGLRPDVVVGDHRLSLSVSARLAGVPYLSLVNAYWSPYTPTRRLPMPELPIGRVLPSA
                     LAAWLFRAVWPVASALQCRPLNRVRAEHGLAGLGNDWFSVYADADRTLYVDAAELVPT
                     VDLPPSHTYIGPVSWSPAVPLPEWWDALPDDRPLVYVTLGSSGRAELLDVVLQALAGL
                     DVLVMVTTAGKAIPRSVPSNARLVDFAPGERLAARADLMICNGGSLTVYQALAEGKPV
                     LGIAAHMDQQLSMSYVESAGVGVCVRSDSLSIAGLRARVRDLLDDSAIHLRAREMGRS
                     IAGYDPVARLTAVVDEVLRG"
     gene            complement(24226..25923)
                     /locus_tag="P5537_03450"
     CDS             complement(24226..25923)
                     /locus_tag="P5537_03450"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013714.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HRV77130.1"
                     /translation="MESRNRSGRLPVGVLAELNAVLGAEHVLTTPEALDQYSRCTIPW
                     RTECAVVVFPASTEEVAATMRIAARHGIPVWPSSKGRNWGYATTLACTDGAMVMILER
                     MNRILEVNEELAYAVIEPGVTYEQFNAHLAEHGHKLWIDCIDGTAQGSVIGNAIERGV
                     GETPYGDHFGNLCGLEVVLADGEVVRTGSTREGLHTWHTHKWGVGPYLEGLFTQSNLG
                     VVTRAGIWLMPAPECHESFVFQVSDESHMPAVVDAYRKLALGGVVTTKMHLINDFVSL
                     TILTQRIAEPVPQGGALTDADLGMLRSKYGVAPWSCAGAIYGTRSLVREQRRLIRKAL
                     APYGRLIFVADWQIPWIERIVRWAWKSEALRGMTQRLAGTSLPVLESAPFVHKIQRGV
                     PTEYFVKHAYYRARRPPPVGAVHPARDNCGLIWFAPILPFTNAHLWPYVSDTKALFAA
                     HGFDYYVAMLLMNPRSMICLMAIIYDREDPDEVERSRQLYAALLDHMCKRCYEQYRAG
                     LAAWDTLHDDAPELKRLNDRIKAALDPANILAPGHYGVGTSEREARHPTTPDTGGQA"
     gene            26133..26879
                     /locus_tag="P5537_03455"
     CDS             26133..26879
                     /locus_tag="P5537_03455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-CTERM/exosortase system-associated
                     acyltransferase"
                     /protein_id="HRV77131.1"
                     /translation="MSLFGLFNLGKGFREHFRIDAALDDTLREDVYRIRHEVYCEELR
                     FEPERADRREIDTFDAHSLHCLLRRVAEPHTLVGCARLVLTDPKDPDAPLPFERTCAG
                     ALDPRIVDTAALRRDRIAEVSRLAVRAPFRRRKGEDRVAASISNEDFGSATQPRFPYI
                     PIGLYLGAISLAVHKDIETLFVLTEPRLASHFSKLGVDIRQIGAPISHRGVRVPSMMD
                     VDSIIRNMRSLMRPFWRAVHEEIGRGFEKP"
     gene            complement(27061..28953)
                     /locus_tag="P5537_03460"
     CDS             complement(27061..28953)
                     /locus_tag="P5537_03460"
                     /EC_number="6.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050218 - propionate-CoA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0019629 - propionate catabolic process,
                     2-methylcitrate cycle [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="propionate--CoA ligase"
                     /protein_id="HRV77132.1"
                     /translation="MTDYQQFHRRSIEDRDGFWAEQAQLVHWNKPAEQVCDYSKPPFV
                     KWFKGGETNLCYNAVDRHAATRPNDRALVYISTETDEEKVYSFAELQREVERMAAIYQ
                     ELGVQRGDRVLIYMPMIAEAAFAMLACARIGAIHSVVFGGFAAGSLATRIDDAKPVLM
                     VSSDAGMRNGKPVPYKHLVDEACKLAEFPPAKVLIVDRGLDKGFAKVAGRDVDYAELR
                     ARHMDAQVPVVWLESSEPSYILYTSGTTGKPKGVQRDTGGYTVALTASMKHIFTGGAG
                     ETMFSTSDIGWVVGHSYIIYGPLLAGMATIMYEGTPLRPDAGIWWQIVEKYRVTVMFS
                     APTAVRVLKKQDPAFLKKYDLSSLKHLFLAGEPLDETSHQWIMEELGIPVIDNYWQTE
                     TGWPMLAICRGVEDSPIKLGSPAFPVYGYDLRIFREDGTECGANEKGIVGILPPLPPG
                     CLSTVWGQDERFVSTYFTLFTEPVVYSSSDWGIKDDKGYFTILGRMDDVINVAGHRLG
                     TREIEEAVQTHPAIAEVAVVGVADELKGQMPMAFAVVKNAADVDTPEKRAALEKEVMK
                     KVDESLGAIARPARVHFINGLPKTRSGKMLRRSIQALAEGRDAGDLTTIDDPSTLEQI
                     KVALKG"
     gene            complement(29091..30263)
                     /locus_tag="P5537_03465"
     CDS             complement(29091..30263)
                     /locus_tag="P5537_03465"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009975 - cyclase activity [Evidence IEA];
                     GO_process: GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HRV77133.1"
                     /translation="MDQAPTTDAEGRLPRILVVDDSRMVRASIVKHIRGRFEAREEPD
                     GEAAWEALLVDPAIEIVLTDIGMPRLDGYGLLERLRASKLPRVRDLPVVIISGDEDES
                     ARERALALGANGFVTKGTGGVELLATLMSLLRLSKAQGELERSRAALERQSPVDPESG
                     LATEAYLEHHGAQAVAEARRRQADIGAMVIGIDQFDELAARYGVQVVQLILRKLGKLV
                     SGRIRAEDTLSQHGQACFALLSPGIDRVSTCAFALRLREGVEKLVMAYRDERIRVTLS
                     IGVASAVADGREAIGALLALAQERADQARAAGGNRVVAEGGVVDPAAIERELARIPSV
                     DGALRLLRAGARDEVAGQLPALVGALLPLLELLESRLQSGLPLARLREFHDKGGGG"
     gene            complement(30274..31269)
                     /locus_tag="P5537_03470"
     CDS             complement(30274..31269)
                     /locus_tag="P5537_03470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HRV77134.1"
                     /translation="MNPFKAFVIDQDENRKVVAGMRTMSVDQLDAGEVTIRVHYSSIN
                     YKDALAATGAGKIIRRFPCVGGIDLCGEVVGSADARFQPGDKVIATSFDIGVAHHGGF
                     AEYARVPAGWVVPLPAGLDLFEAMALGTAGFTAALGIVRMEDNGLAPANGPVVVTGAT
                     GGVGALAIDMLAQLGYHVVALTGKEAEADYLKMLGAAEILLRSSIDFDKVRPLEAARW
                     AGAVDNVGGQILHWVLATMKQAGTVASIGNAASFNIDTTVFPFILRGVSLLGVDSGYM
                     GFPTRQRVWDRLATDLKPRHLAAITRTIDFDALPGAFDDFIHGRVKGRTVVRIGA"
     gene            31453..32316
                     /locus_tag="P5537_03475"
     CDS             31453..32316
                     /locus_tag="P5537_03475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004379830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDOD domain-containing protein"
                     /protein_id="HRV77135.1"
                     /translation="MPLLPSPLPSSAAYIDAFSRAGLPVLRHTARAFEELRGAEHPPG
                     AREIAAVVLADPLMTLRLLTHLESNRRASQNHDITTIERAVLMLGVEPFFTAFSALPT
                     VEDTLAAHPKALVVVLKLIARARRAATLAREFATMRRDHEVQEITVATLLREATEIVC
                     AIHAPTLTLEAIARRQADPARPAAEVQREVFGVSAAELQHALIAAWRLPGLLAGLLDS
                     DHADNPRVRTITLATRFARHQARGWTSPALQDDLAELEALLHQPRESLLQRLGVPADL
                     RAGLLPDTQAE"
     gene            complement(32357..32485)
                     /locus_tag="P5537_03480"
     CDS             complement(32357..32485)
                     /locus_tag="P5537_03480"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77136.1"
                     /translation="MKKALLRLALVVLAAIVLGLLFAAYQQPALLLDFSNLILLCG"
     gene            complement(32482..33705)
                     /locus_tag="P5537_03485"
     CDS             complement(32482..33705)
                     /locus_tag="P5537_03485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014236969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HRV77137.1"
                     /translation="MSLPSSPLAAPAFLRRPAVVMACGALILTLAMGVRHTGGLFLQP
                     MTLDHGWSRELFSFSIALQNLLWGVFQPFAGAFADRHGAGRTLAGGAVLYVLGLVVMA
                     YADSALGLNLGAGLLIGMGLSGTTFSVVLGVIGRMAAPEKRSLALGIASAGGSFGQFA
                     VLPVGQGLITAVGWQDALLWMALGIAFIIPLSAAVTGTSARGGGVEQSLRQALAEAMR
                     TPSFHFLFWSFFVCGFQTAFVMLHLPAYVVDMGLSANIGMSAVAMIGLFNIFGSFLSG
                     WLGGLYSKKWLLAWIYALRIVAILALMLFPLSPLTLYVFAAVMGLLWLGTVPLTSGLV
                     GCIFGMRYVGMLYGIVFLGHQIGGFLGAWLGGRIFDLSGSYEMAWWLSIALSVMAAAL
                     SLPVREAPLARLAAR"
     gene            33815..34390
                     /locus_tag="P5537_03490"
     CDS             33815..34390
                     /locus_tag="P5537_03490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HRV77138.1"
                     /translation="MSIGSAVLLGLVVLALVYGVVIYNGLVQLKHNLAKAWANIDVLL
                     KQRHDELPKLVEVCRQYKQFEQDTLARVTEARARVAQAREARDVAALGAAENLLRGGL
                     GQLFAVAEAYPELRANEHFMQLQSRITALENAIADRREWYNEAVNVHNVRIEQLPDLL
                     IARPLGYAEQPLLQFSVAEKADVDLKALFGS"
     gene            34525..35427
                     /locus_tag="P5537_03495"
     CDS             34525..35427
                     /locus_tag="P5537_03495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77139.1"
                     /translation="MLVHLRHLRADLALPAIQLGAIALALRLGPGPGSLAALAVLLGS
                     GLFGTLRALRHARLIADTPTARVASAAQGYTELQGRGAALAGDPLLSPANALPVLWYR
                     LRIERRQRDGKWRLVSADTSDASFLLDDGSARCVVDPEGAEMLVRRCDVFVRDDLRYT
                     QWSLIEHDKLYVIGDFATLGSAEVRTDTAAEVRELLAVWKADRPALLQRFDLDGDGEI
                     GLREWEHARAQARREVRQRQAEALAAPELHLMRRPSDGRLYLISDLAPERIGRQYRWL
                     AAFHAAVFLGASAATAWFAQIGVF"
     assembly_gap    35556..35655
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(35971..37905)
                     /locus_tag="P5537_03500"
     CDS             complement(35971..37905)
                     /locus_tag="P5537_03500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HRV77140.1"
                     /translation="MPLLAVDNACLAFGHVDLLDHVSFQLDAGERVALIGRNGSGKSS
                     LLRALAGQAALDDGTVWRQAEMVTAYVPQEPDFELERDVFETIADGLGAAARLLVDYH
                     AAMLEVAEQASPAALARLDGLQHAVEAAGAWRLNQRVEQVVERLGLDPAAKVSSLSGG
                     GVKRVALARALVAEPDLLLLDEPTNHLDLDGILWLEGLIRDFRGAVIVITHDRIFLDS
                     VATRIIELDRGKLASYPGRFSDYQRRKAEELEAEEKAAARFDKFLAQEEVWIRKGVEA
                     RRTRNEGRVRRLESLRRERAARRDRLGDVSLAVDTGDKSGQMVAELTHVSKRYGDKVV
                     VRDFSTRILRGDRIGFIGPNGAGKTTLLKLILGEVEPDEGTVRRGTRQTVAYFDQLRA
                     QLDPELPLTEVISPGSDYVEIGGEKKHVIGYLGDFLFAPQRARSPVKSLSGGERNRLL
                     LARLFARPANVLVLDEPTNDLDIETLDLLEELLAGYDGTLFLVSHDRAFLDNVVTQVI
                     AAEGDGRWGEYAGGYGDWQRVQVRRAEEAAAREATARESARRSVPPPDKARAAEPKAA
                     SRPTRLSFNEKRELEALPERIAALEDEQAALHARMADPALYQNAPQEVAQIKARLEAL
                     DGEIDAAMLRWEALESRAAG"
     gene            38088..40115
                     /locus_tag="P5537_03505"
     CDS             38088..40115
                     /locus_tag="P5537_03505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific recombinase"
                     /protein_id="HRV77141.1"
                     /translation="MEKLLERFGQADQDPVRLWSALVDKLRPARPTEADTAAGNLREL
                     GNLLARRPDLLANLRKAVLELFAGRKQVTMYVSSGLLPSTGFFSETSRRFGSRMLPEL
                     LDTAHLKDLLSAVFHRVDDEEWVRAIPDEDWQDFLRLLVGHQTPMFEEDASPLPSAVG
                     EILESLRVLSFHVSAIGLDRELVRIDPHLEEHESPFLAQNAELLAYIGHYKEWWTTPG
                     ALIADDKHLTVMLHQCDEVLQRVRKRAMRVGTSLTLTFKLERLRQHLERIHDLIALLG
                     ELRTRRVVEDAAPRIVRLFKTLVRAECRKNILADYWGQNVELLSLRMTESASRTGEHY
                     ITSSRSEYFGLFASAALGGLIIAFMAANKIVLGSQGMAPLNEMLSFCLNYGLGFVLIH
                     MLGGTVATKQPAMTANAIAASIGEAKGKTRDLEALADLIVRTIRSQIGAILGNIGVAI
                     PVAVGVGVLIHLATGSHFISPEKAHTLLDEIHPLGGAAFFAAIAGVCLFMSGLIAAYY
                     DNLSAYNRIPQRLTQLRGLRRLLGERRLHGLADYVEQNIGALAGNFFFGFLLGGATGL
                     GVLFGLPIDIRHIAFSSAYLGYASAALDFSIPLTTAAIAFAGVLLIGLTNLAVSFALT
                     LSVAMRARRITFAQSRSLGGLLLRRLLRTPHAFLFPPRADEAALGPTPPNG"
     gene            40134..40208
                     /locus_tag="P5537_03510"
     tRNA            40134..40208
                     /locus_tag="P5537_03510"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:40167..40169,aa:Arg,seq:cct)
     gene            40306..40965
                     /locus_tag="P5537_03515"
     CDS             40306..40965
                     /locus_tag="P5537_03515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HRV77142.1"
                     /translation="MPRYCQVLFDLDGTLIDSAPAILASYRDAFASTGHRPVIAIDAG
                     IVGPPLLETLRMLAGTRDAAVIDALAAGFKASYDSTGYRQTAAYEGVDAMLRRLGAAG
                     CTLSIATNKRLLPTRLILEHLGWSGHFAAVYALDLFEPRLPDKAAMIARLLQDRGIDR
                     ADAVYVGDRGEDGESADANQLPFIAATWGYGSLEAGEMAPHWRAVASPAALADEILGE
                     A"
     gene            complement(41004..41783)
                     /locus_tag="P5537_03520"
     CDS             complement(41004..41783)
                     /locus_tag="P5537_03520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HRV77143.1"
                     /translation="MPARRRLLACALAIPLALALTPCARADLVSTLARVKPSVVGVGT
                     YQRTRSPAFVFRGTGFAVGDGMSIATNAHVLPDQVDSAKLEQLVVVLPGDGLTGAVRP
                     VRVVASERAQDLALLRLESGPALPALRLAGGGGVVEGQEVAFTGFPIGAVLGMTPVTH
                     RGIVSAITPIAIPQANSRDLNPALIRRLATDPFRVYQLDATAYPGNSGSPLYDPATGE
                     VIGVLNMVFVKSTKEKVLSDPSGISYAIPVEYLHRLIASQR"
     gene            complement(41798..42775)
                     /locus_tag="P5537_03525"
     CDS             complement(41798..42775)
                     /locus_tag="P5537_03525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HRV77144.1"
                     /translation="MNTRKNRTSLAGRTARLASRARGRARGAVAVALALAWSVPAVAG
                     EGAFERALAEQARYLATEALAYEHGEGVPRDQPYAALLYCESARLGDAEGMYALGWMY
                     ANGRGVERNDAYAGTLFAMAAAKGDEHAERMLRYTGEYTGEVPDCLHTPSSQIVQRWP
                     VEALIARLPAARQAVARMLAELAPKYGVRPEFALAIGLTESALNPQALSPKNAMGVMQ
                     LIPATAERFNVGKPYDPEQNIRGGLAYLRWLLAYFEGDIALAAAGYNAGEGAVDRYRG
                     VPPYRETRAYVERILRHVGQDRHPYDSRVVAPSPMLRKLRLALEQEHES"
     gene            complement(42922..45723)
                     /gene="prsT"
                     /locus_tag="P5537_03530"
     CDS             complement(42922..45723)
                     /gene="prsT"
                     /locus_tag="P5537_03530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-CTERM system TPR-repeat protein PrsT"
                     /protein_id="HRV77145.1"
                     /translation="MSQVRSRRSRWSGRAASGVAAAALSVLLLAGCSETPEEMVVSAK
                     AFIEKQDLDAASIQLKNALQQNGNLAEARFLLGRINLRQGNVAGGVKELQRALELGHP
                     RDVVAVELAPAFVAAGEVDKLFAEFGDPRVSEPKALAAVLAALGDAHLARRDVDKARA
                     SYLESIAAAPDEARSHIGLARTTALKGDLAAAEAEVREAVRRSPEAAEAHALLADLLI
                     GQGRAPEGVEALREVVRLQPKSVNGHFALVSQLLRGGDMAAADAALESMRSVAGNHPL
                     TRYLVALRHFRENRLTEARDDVMQVLKDAPQLLPADLLAGTVLVRTNEHALARTHLDR
                     VLQAVPGHLGARQALIVSHLATGESKRALELLQPLLQAQQPSARLLGLAGQVFLANGD
                     FERSEEYFELASKASPDDPRARMRLGVARMAGGDIDSAFEDLESAARMDESGIQADLA
                     LVVGHLRRGEIDKALAAQAELERKQPDNVLVDNLRGGLMLARRDIPAARAAFEKALAR
                     QPGYLAAAINLARLDLAERKPQDAIARLEAVVKNDPKNVEALLTLAEIQRATGAAAPE
                     VLRTLERAEAASPGSVRANLAIIQHLLSQRQATQALQVAQKVAAAHQSEPRAIEALAR
                     TQLAAGDSQQAIAALNRLVNLLPASPQPLVALADVHRSLKDGHAAEQALRKALSIAPD
                     LIDARQRMIALALERNDRKLALQLAGEAQSRQPELPAGYLLEGDVHAVASQWSEAAAA
                     YRKALDRKGGGQAAARLHSALVRADRKADAARMADAWLKDNPSDLVLRGYLGELALGE
                     KRYADAVKIFARMSEMAPQNPILLNNLAWAANEVKDPKALEYAEQALRLAPENPAIID
                     TVGTIQVESGAVDAGLANLRRAVSIGPDLLPLQLNLARALVKAGKKDEARTQLQALMP
                     RLKDGTPMHQQAAALMKEL"
     gene            complement(45720..47093)
                     /gene="prsR"
                     /locus_tag="P5537_03535"
     CDS             complement(45720..47093)
                     /gene="prsR"
                     /locus_tag="P5537_03535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045893 - positive regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-CTERM-box response regulator transcription
                     factor"
                     /protein_id="HRV77146.1"
                     /translation="MNSTSDKQRTLLIVEDDLALQKQMRWAFDACETVVASDRESAIA
                     QLRKHEPAVVTMDLGLPPAPDDVSEGFKLLREILTLAPDTKVIVLTGQHDRENAVKAV
                     GLGAYDFFAKPFEPELLNLTIERAFRMHDLQMENARLAALEGSPLSGLLTRDPGMLKI
                     CRTIEKLASASATVALLGESGTGKEILARGLHMLSPRARERFVAINCAAIPDTLLESE
                     LFGYEKGAFTGAVRQTLGKIETANGGTLFLDEIGDLPLALQAKLLRFLQERSIERIGG
                     REEIPVDVRIVCATHRDLKAQIQAGVFREDLYYRLAEIVIEIPALREREGDATFLAHA
                     FVQRFAKENGRRAPMLADDALSAIEAHRWPGNVRELENCIKRAVIMADGDCISAEDLG
                     LAAGDEDLSIFNLRQVREDAERAAVLKVIARTNGNIARAAEILGVSRPSLYDLLGRFG
                     LKKENGS"
     gene            complement(47097..49166)
                     /gene="prsK"
                     /locus_tag="P5537_03540"
     CDS             complement(47097..49166)
                     /gene="prsK"
                     /locus_tag="P5537_03540"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-CTERM system histidine kinase PrsK"
                     /protein_id="HRV77147.1"
                     /translation="MAEVAIWSYGVAAVAFAFFALYIFFAWRGALPGGVLFAAVAISG
                     LWAACSALAARGDGALIGTVAVILDVVRVAAWYAFLIVLSRPLWGGWLRWPAYAAVAA
                     VSLQILALMLEWAGLAGTLPVEPVIGAWLTHAVVGLMLVEQLYRGMPSVSRWGLKPLC
                     LALAAGYIFELYLFADALLFSRLDADVLATRGIAHALLIPLIAIAGTRSPSWTLRMSV
                     SREVVFHSTALAGAGLYLLVIAGAAYYVRYFGGDWGRALQMALLFAGLVLLGALLFSG
                     AVRARLRVFISKHLFPYRYDYRAEWLRFTQALSSADRSLDLGQSVIKALSDLVESPGG
                     ALWLADGYGKCKLHSRFNHPVVDAVDSLDSPLCAFLAGRGWVVDLEEYRMQPGRYEGL
                     VLPAWLSHLDDAWLVIPLQTAERLIGFVVLSSPRAPFDIDWEVLDLLKTAQRQAAGYL
                     DRMLAAEALLEARKFDSFNRMSAFVVHDLKNLVAQLSLMLKNAQRHRDNPEFQQDMLE
                     TVANVEARMRGLMTQLQEKRSIDPPRALDLPALLRAVCDSKRGQLPVVEIALEGAGSV
                     EVSAHPQRLERIVGHVVQNALDATPQDGKVTLTLAAGTDGRANVVVEDNGCGMTAEFV
                     RERLSRPFQTTKSSGMGIGVYETRQYLEEIGGALHYDSEVGRGTRVTIELPRIRREDG
                     QSTAMGT"
     gene            complement(49242..50627)
                     /locus_tag="P5537_03545"
     CDS             complement(49242..50627)
                     /locus_tag="P5537_03545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03013 family PEP-CTERM/XrtA system
                     glycosyltransferase"
                     /protein_id="HRV77148.1"
                     /translation="MLKVFSHYLPTHTLQQVLFDALTLFAVVLGAVALLVTPTSAVDW
                     AVCIPSALTFAASMIALNAAMGLYRPVYQRSHRQAFARVALSLTVSVPVAYLVFGLLP
                     WSEIEPHSLQVSVLLLLCFLLLARGLVNQRQASALFVPRVLIVGTGRDARMVHQDLTR
                     PLQRSVDVVGFLPVGGNERIEVEPREVLPPGSLLDVVRNLRVDEVIVAVRERRGGVLS
                     LRELLDCKLLGTRILDLSSFFERVQGQVRLDSLRASWLIYGDGFRQGWTRTFVKRCFD
                     LVVGTVLLLVAMPVMVLTALLIVLEDGAPIFYSQERVGRGGRPFRVIKFRSMRRDAEK
                     DGKPRWASSNDDRVTRIGRFIRKLRIDELPQLFNVLNGDMSLVGPRPERPYFVDQLTQ
                     QIPFYAVRHCVKPGVTGWAQVRYQYGASVDDAAEKLQYDLYYVKNHSLILDTLVLFET
                     VRVVLTGEGAH"
     gene            50934..51383
                     /locus_tag="P5537_03550"
     CDS             50934..51383
                     /locus_tag="P5537_03550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MaoC family dehydratase"
                     /protein_id="HRV77149.1"
                     /translation="MTQPQRDFSEVYGLGFEDLHVGRTASVSRTVSEADILMFAGVSG
                     DTNPVHLDEEFAASTMFGGRIAHGMLSAGLISAVFGTRLPGPGCIYLSQSLKFKAPVK
                     IGDTVVARVTVKELKAEKRRAVFSTVCTVGDKVVMDGEAEILVPARG"
BASE COUNT         8432 a        18012 c        17191 g         7935 t
ORIGIN      
        1 aggggggccc gggacgcggg gtggttcatg taggagcgcc ggcaggcgcg aaggcggcgg
       61 tggagtgctg cacgcgcgtc gattgccgca ccgccgggtt cgcagctgcc gcagcgcctg
      121 cagggtggct ggggacgacc cggtggtttc agcgtgcgat ggcgggccgg gtgggggtgg
      181 cggcgtcggt gcgggcttcg accagcttga cgactgcgag cgagatgttg tcgccggtgc
      241 caccggcgcg ctcgcggccg agcgcgacca ggcgttctgc ggcggcacgc gcaggaaact
      301 cctgcagggt cgaggcgagc tcgaactcgg tgaaatgtgc ccacagaccg tccgagcaca
      361 gcaggaaggc gtcgccgccg aggggcgact cctcgcgacc gtagtcgatg cgcggctcgc
      421 ggtcgctgcc caggcaggat agcagcacgt tgcgctgcgg gtgacggagc gcgctgcgat
      481 cgtccaggcg gcccttgcgc accaactcgg ccacgagcga gtggtcgccg cttaccgaca
      541 tcgtgcgcgt gccgcgaaag tggtacatgc gcgaatcgcc gcagtgcgcc cagtaggcct
      601 tgccctgctg catcatgaag accaccgcgg tgctgtgcgg gtcctgctcg ctggtgaagc
      661 gggtcagctt gatgacgacg tgggcctcgt cgatgatgct gcgcagcagg tgctcgggcg
      721 tctcgtgcag cggcgcgtag gcctcgaagt tctgccgcgc gcgcatcagc acctgctcgg
      781 cggccatggc gccaccgcta tggccgccca tgccgtccgc gagcaccgcc atcatcatgc
      841 ccgggcgctt cgggtggccg aacagtgcga cgcggtcctg ctgttccttg cggtcgccca
      901 gatgcatggc gacacaggtt tcggcggtga aaggcatggg gatagggtgg acgcgatcgg
      961 aacggatcac gggatgatat caacccggca cagggctcag gcggcaggat gccgtccggg
     1021 gctaaggccg ggcgtgaaat ccgtcacgcc cggcgcggtt catcacgagg ccgtaccgag
     1081 gcgggcgtcg atcagctcga tccagtgcag caccggcttg tccgtgcccg cctgcaggtg
     1141 ggtgatgcag ccgatgttgg ccgaggcgat ccgcccggca cccccctcga gcagggcgtc
     1201 gagcttgttc gcgcgcaggc ggccggaaag ctcgggctgg aggatcgagt aggtgcccgc
     1261 cgaaccgcag cacaggtggg catcgcgcac cggggtgagt tcgtagcccg ccgccgtcag
     1321 cagggactcg accgtgccgc ggatgcgctg gccgtgctgc agcgtgcagg gcgcgtgcca
     1381 ggcgagcggc tcgcgcggct gcgcgcgggc ggcgagccgc gcccgcaggg cctcgccctc
     1441 ggcgaggacg agctcggcga tgtcgcgcgt gagctcggcg actcgccgcg cgcgctcggc
     1501 atacgccggg tcgtgctgca acaggtggcc atagtcgcgc acctgcacgc cgcagccgga
     1561 ggccgtcatc acgatcgcct cgatgcgccc ggcctcgatg tcgggccacc agacgtcgat
     1621 gttgcggcgg gcgtcggcgc gcgcgccctc ggcgtcgtcg aggtggaagc gcaccgcgcc
     1681 gcagcagcca gcgccgggca gctccaccat cgagatgccg agggcgtcga gcacgcgcgc
     1741 cgcggcggcg ttgatcgagg gcgccatcgc cggctgcgcg caaccggcga gcgcgatcac
     1801 ccggcgcgcg tggcgcggcg ccggccatgc accggccggg cgcagcgtcg gcaccttgtc
     1861 ctgcagcgac ttgggcagca gcccgcgcac cgcccgcccc gcccccatcg ccaggccgaa
     1921 cagcctgggc cgcggcacga actcgcgcag cgtgcgccgc atcagcgcct cgccaccatg
     1981 gcgcggcacg cgctcggcga ccaccgcgcg gccgatgtcg agcaggcggc tgtagtgcac
     2041 gccggaagga caggtggatt cacacgaccg gcaggtgagg cagcggtcga ggtgcaggcg
     2101 ggtcttctcg gtgggctcgg caccctcgag aacctgcttg atcaggtaga tacgcccgcg
     2161 cgggccgtcg agctcgtcac cgagcagctg gtaggtcggg caggtggcgg tgcagaagcc
     2221 gcaatgcacg cacttgcgca ggatttcctc ggcctcgcgg ccctcggggg tgtcgcggat
     2281 gaaatcggcg agctgggtct gcatggctca gaactccggg tagagacggc cggggttgaa
     2341 gatccccgcg gggtcgaagg cctgcttcaa tcggcgatgc accaccgcga gcggcgcggc
     2401 caggggctgg aacacgccgg cagcgcgatc gccggcgcgg aaggccgtgg catggccgcc
     2461 aagctcgacg gcgcgcgcgc gcaccgcctg cgcatcggcg gcgcccgcga gccagcgctg
     2521 cgcgccgccc cactcgacga gctggcgccc gggcaggccg agcgcgggcg cggtcgaggg
     2581 cacggacagc cgccacagca cgctgccctc ctctaccgcg aagccgggca gggtctgctc
     2641 gcgcaccgcg gtccacaagg cctgcgccgc gccaggcgcg agcgcctcgc cgccgagccg
     2701 cgcacaggcc gcctgcaccg ccgcctcggc gcccgaaagg cgcaggtgca gcacaccgtc
     2761 ctgccacagc gtcgccgaca ccggcagcgg ctggccgccc cattcgttga cgcgccgcag
     2821 cgcgctcgcc tcgtcgagct cgaagcgcag cgtggcctcg gccaccggac gcggcagcac
     2881 cttgagcgag acctcgagca ggatgccgag cgtgcccagg ctgcccgtga ccaggcggga
     2941 gatgtcgtag ccggcgacgt tcttcatgac ctggccgccg aagcgcagca cctcgccgcg
     3001 gccgtcgagc agcttgacgc cgagcatgaa gtcgcgcacc gcgccggcgt tcgcccgccg
     3061 cggcccggaa agacccgcgc cgacacagcc gcctaccgtg gccccggggc cgaagtgcgg
     3121 cggctcgaag gcgaggtact ggcccctgtc ggcgagcacc gcctcgagct cggcaagcgg
     3181 cgtagcgccg cgcaccgtca ccaccagctc ggtgggctcg taggcgacca cgccgtggtt
     3241 ggcgcgcaga tcgaagggct cgcccgcgag cggcccgccg tagaaatcct tgctgccgcc
     3301 agcgcgcagg cacagcggcg tgcgcgccgc cgcggccgcg cgtacgcgct cggcccattc
     3361 cttctcgatc gtcgtcatcg tctcatcgtc cagtcattca tttgcccgac cgcgccagcg
     3421 gtcgtcggtg tgttgccgcg ggcgacgccg cgcccttccg atcaccgcgc cgtttcgtgc
     3481 aggagcgccg gcaggcgcga aggcggtcgt cggggcaggc aggtgcatcg atggcggagg
     3541 cgccggttcg cgcctgccgg cgctcctaca tgaaccgtca agacgccggg tggagcggcg
     3601 caactcacgc acccggttca gaagcgcggg atgtccggat acggcacatg gcccttgctc
     3661 accttcatgc gcccgtactc ggcgcagcgg ttgagcgtgg ggatcgcctt gccggggttg
     3721 agcagcccgg gcgggtcgaa ggccgccttg acgcggaaga actggcgcac ctccgccgtc
     3781 gtgaactgcg cgcacatctg gttgatcttc tccagcccga cgccgtgctc gccggtgatg
     3841 gtgccgccga gcgccaccga gagctcgagg atctcggcgc cgaacgcctc ggcacgctcg
     3901 agctcgtcgg gctggttggc gtcgaacagg atcagcgggt gcaggttgcc gtcaccggca
     3961 tggaagacgt tcatgcagcg caggccgtac ttgccctcca tggcctggat cgcggtgagg
     4021 atctcgccga tgcgcttgcg cgggatggtg ccgtccatgc agtagtagtc gggcgagatc
     4081 cgccccgccg ccgggaaggc agccttgcgc ccggcccaga agcgcaggcg ctcggcttcg
     4141 tcgcgcgaca cgcggatctc gctggcgccg ctttcctgca gcaccgcgcg tacgcggtcg
     4201 acctcctcgg cgacctcctc cggcgtgcca tcggcctcgc acagcaggat cgccttggcg
     4261 tcgagcggat agccggcacg cacgaactcc tcgaccgccg cggtggcggg ctggtccatc
     4321 atctcgaggc cggcggggat gatgccggcg gcgatgatct tcgccaccgc gtcgccggcg
     4381 cgcacgacgt cgtcgaaggt cgccagcacg cactgcgcga gctggggctt gggcaccagc
     4441 ttgacggtga cctcggtgag caccaccagc atgccctcgg agccggtcac cagcgccagc
     4501 aggtcgtagc ccggcgaatc gagcgcgccc gagccgatct cgacgatctc gccctcgatg
     4561 gtgacgccgc gcacgcgcag caggttatgc accgtgagcc cgtacttgag gcaatgcacg
     4621 ccgccggcgt tctcggagac gttgccgccg atcgagcagg cgatctgcga ggacgggtcg
     4681 ggcgcgtaat acaggccgta gggcgccgcg gcctcggaga tcgccaggtt gcgcacgccg
     4741 ggctgcacga cggcagtgcg cgcgagcgga tcgagcgcga cgatgcggtt gaagcgcgcc
     4801 agcgacagca gcacgccgcg ggtgtgcggc agcgcgccgc ccgacagccc ggtgcccgcg
     4861 ccgcgcgcca ccaccggcac gcccatctgg tggcagatgc gcagcaccgc gaccacctgc
     4921 tcctcggtgc tcggcagggc cacgaccagc ggcagcgcgc ggtaggcggc gaggccgtcg
     4981 cactcgtagg gacgcaggtc ctcggcgtcg tacatcagcg tgccggcggg cagaacccga
     5041 ctcagcgcct cgatcacgcg cgccttgtcc accgcggaaa aatcgccctc ggtctcgccg
     5101 aacgccagta cttcgttttc cagcatcatc gtcgtctcct tgccaagcgc ggccgatcgc
     5161 gcctcgtcca ccgcgccgcc accgcgaaat ccgcgccgac gcagcggccc ctccagcctg
     5221 cagcgagtat agagggtcgc gccgggcgcc tgcttgacgc ctcttctcca gcgccttgaa
     5281 gaaaattcaa cccgcgcggc ggtgcctcaa ggcagcacgg cctgaagcca gtccgcgaac
     5341 gcggcgcatt cccagcgctc gagcgcaccc gggcgccagc acaggtagtg ggcgtggggc
     5401 gagcgcagcg ggcgcgagga cagcgccagc agccgcccgc cgtcgaacca cgccgcaccc
     5461 aggcgctggc gtaccaaggc gacgccgaag ccgctcgccg ccgcatcgta ggccagcccg
     5521 aggtcgttga actgcgcccc gcgcgcgggc tcgggcaggg tcagcccgca atgcgcgaac
     5581 cagttcgacc acggctcgag cgggctgcgc acgagcgccg tggcgctgca ctcggccacg
     5641 ctggcgaagc cgtcgaaggg gccgtgctcg gcgaggaagg cggggctgca ggcggggacc
     5701 acgtcgtcgc acagcagcag gcggtgctcg aggtcggtgt agccgccggc gccgtagcgg
     5761 atctcgaggt cggcctcctc ggcgacgacg tcgcgcaagg ggatggacac ctgcagcgtg
     5821 agctcgatct ccggccagtc gcggcggaag agctcgagtt tgggcatcac gaactggcgg
     5881 cagaacgagg gcgtcaccgc cacccgcagc cgcggcgcca cggccggcgc gcgctcgccc
     5941 ggcagctcgc gcagcgcggc gagggcgacg ccgacctgct gaaggtaggc cgcaccctcg
     6001 gcggtcgggg tgaagtcgct gcgcgagaac agccgcacgc cgaggtggga ctcgagctgg
     6061 cgcaggcggt ggctgaccgc gctcacggtc acgcacagct cttcggccgc gcggctcgcg
     6121 ctgcgcaggc gcgcgaccgc ctcgaaggtg agcaggcact ggatgggcgg gatgcgtcgt
     6181 tgggccatgg cggcggtgcg tgtggaggcg tacgggaaga cgcgaagacg gcgaacgcgc
     6241 cgattatgcg cgcgacggac gccgcccgga atcggcgacg atgccgcacg accgcgccag
     6301 gctcgggaca cgcgaggtgt gcggtctggc agtttgtcat taccatgagg gccgggtgca
     6361 gcctcggcca tcagggggcc tcggcccgtc ctcgctccgt cccgtcctcg cttcgcgtcc
     6421 gccttcggct tcatcctcgc ccccgccttc gcccgcccgc ctcccatcca tgtcccgccc
     6481 gcaccgactg ctgcccttcc tggcctggcc cgcgcaatgg cgcgagcacg ggctgcgcgg
     6541 cgatctcgtc gccggcgtca cggtcgcgct ggtgctgatc ccgcaggccc tggcctacgc
     6601 caagctcgcc ggcctgccgc cgcacatcgg cctctacgcc gcgctggtgc cggcggtggt
     6661 ggcggccctg ttcggctcct gcggccagct gtccaccggc ccggtggcgc tgaccagcct
     6721 gctcgtgggc gccagcatcc tgccgctggc gggcagcccc ggggacgacc tcgtcggcct
     6781 cgcgctgctg ctcgcgctgc tgtcgggcct gttccagctc gcgctcggcg tgctgcgcct
     6841 gggctggctg ctcaacctgc tgtcggtgcc ggtgctgatg ggcttcgtca acgccgcggc
     6901 gctgatcatc tgcctcaccc agatcccgcc gctgctcggg ctggccatgc cgcactccga
     6961 tcatctgctg gtcgatttcg tgcgcgcgct cggcgggctg gacgcgctgc aaccggccgc
     7021 ggtggcgttc ggcgtcggca gcctggtcgc gctgatcgcg ctcaagcgcc tgtggccacg
     7081 cctgcccggc gtgccgctgg tggtggcggc gacgatcgcg atctcggcgt ggaccggctt
     7141 cgcggcgcag ggcggcgcgg tcgtgggcga agtgccggcc ggactgcccg gcttcagcct
     7201 gccaccgctg cggccggaac tgatcgccac gctgctgccg gcggccttcg tggtggcgat
     7261 ggtgagcttc atggaggcgg cctccagcgc caagctgatc tccgggcgca cccggcagcc
     7321 ctgggaccag gaccaggagc tcgtcggcca gggcctgggc aagctcgccg ccgccttcac
     7381 cggcggcctg ccggtgagcg cctcgttctc gcgctcggcg ctcaattacg tcaatgaggc
     7441 gcgcaccggc ctgtcctcgc tggtcaccgc cgccttcgtg ctggtcaccc tgctgtggtt
     7501 caccccgctg ctctggcacc tgcccaagcc ggtgctggcg gcgatcatcc tgcaggcggt
     7561 ggcgggactg atcgacaccg gagtgatgct gcgcgcatgg cgggcgagcc gcgacgacgg
     7621 cgcggccgcg gcagtcacct tcctcgccac gctcgccttc gcgcccaaca tccagaacgg
     7681 cgtgttcacc gggctgatcc tgtcgctcgc gctgctggtg tatcgcggca tgcgcccgcg
     7741 cgtggcgctg ctgggcctgc acgaggacgg cacctaccgc gaccgcgagc gcttcgacct
     7801 gccccacccg catgcgcagc tggtgatcct gcgcttcgac agcccgctca gcttcgtcac
     7861 cgccgccacc ttcgaggacg ccatgcttgg cgcggcgcgc gcgcaggacg gcgtgaagat
     7921 cgtgctggtc tcggccgccg gcatcaacgc catcgacgcc accggcctgc acacgctcgc
     7981 cagcctggtc gagcgcttcc acgtccaggg gcagaccatc gccttctgcg gcctcaagaa
     8041 gcaggtgatc gacgccatgg aacgcgacgg gctgtggtcg cgtatcggca agcaatcgag
     8101 ctaccgcacc gagcaccagg cgctcgacgc cctactgccc accctcgccg ccccggccgg
     8161 gtagacgcgc cggcaggcgc aaaggcgtcg gtggatttcc gtacgcacgt cgattaccgg
     8221 accgacgggt tcgcagctgc cgcagctcct acaggggtcc cgggacgcgt ggtggttacg
     8281 ggaggtccgg gacgcgtggg ggtttgtgta ggaggtccgg gacgcgcggc ggtttatgta
     8341 ggagcgccgg caggcgcgaa agcggcggtg gaacagggta cgcgtgtcgc ttgccggtcg
     8401 gcccgattcg cagctgccgc agctcctgca gcggggccgg accgccgggt tcgcagctgc
     8461 cgcaactccg acaggacacc accgcaaacc ggggcggggc ggcgggggcg ttttgcattg
     8521 acttccgggg ccgactcggc tatcgtgcgc gattcttcgc agacccatca actggagcaa
     8581 caccatgtac gcggtgataa aaaccggtgg caagcagtat cgcgtcgctg ccggcgaaaa
     8641 gatcaaggta gaacagatac cggccgacgt gggttccgag atcaccatcg accaggtctt
     8701 catggtcggt gaaggcgatg ccgtcaagat cggcacgccc gttgtggccg gggcttccgt
     8761 caaggcgacc gtggtctccc acggccgtca cgacaagatc aagattttca agatgcgccg
     8821 tcgcaagcac taccagaagc accaggggca tcgtcagaac tacaccgagc ttcgcatcga
     8881 agcgatctcg gcctaaggcg cagggggtaa tccgacatgg cacacaaaaa agctggcggc
     8941 agttcgcgta acggccgcga ctcggaatcg aaacgcctcg gcgtcaagcg ctacggtggc
     9001 cagttcgtgc tcgccggcaa catcatcgtt cgccagcgcg gcaccgaata ccacccgggc
     9061 gacaacgtcg gcatcggcaa ggaccacacc ctgttcgcgc tgaccaacgg cgtcgtgcag
     9121 ttcgcggtca agggcccgtc gcgtcgccgc accgtgatca tcgtgccgga agcggcctga
     9181 tcgcgctccg gttcgcattg cagcatcgaa agccctatcc cggtggtagg gctttttcat
     9241 tttcggggtg cgcctgccgg cctgccccgc caagaggttg atcaggcatg aagttctttg
     9301 acgaagcccg catcgaggtg tacgccggcg acggcggcaa cggcgcggcc accttccgcc
     9361 gtgagaagta catccccaag ggcggcccga gcggtggcga cggcggccgc ggcggcagcg
     9421 tgtacgcggt ggccgaccgc aacctcaaca ccctgatcga ctaccgctac acccgcagct
     9481 tccgcgccga gcgcggcgag aacggcggca gccgcgactg ctacggcaag ggcggcgacg
     9541 acatcacgct gcgcttcccc gtcggcacgg tgatcaagga ccaggagacc ggcgagctcg
     9601 tcgccgacct cgacgtggac ggcaagaccg tgctgatcgc ccagggcggc cgcggcggcc
     9661 ttggcaacat ccacttcaag tccagcacca accgcgcccc gcgcaagaag accatgggca
     9721 aggaaggcga ataccgcaac ctgcacctgg agctcaaggt cctggccgac gtcggcctgc
     9781 tcggcatgcc caacgccggc aagtcgacct tcatccgcag cgtgtccgcg gccaagccca
     9841 aggtcgccga ctaccccttc accacgctcg cgcccaacct cggcgtggtg cgcaccagcg
     9901 aggcgcgcag cttcgtgatc gccgacatcc ccggcctcat cgagggcgcg gccgagggcg
     9961 ccgggctggg ccaccagttc ctgcgccacc tgcagcgcac gcacctgctg ctgcacttgg
    10021 tcgacctcgc ccccttcgac cccgaggccg atccggtcgc ggacgccaag gcgatcgccg
    10081 aggagctgcg caagtacgac gaggacctgt acgccaagcc gcgctggctg gtgctgaaca
    10141 agctcgacct catccccgag gaagagcgcg ccgagcgcgt ggccgccttc ctcgaggcct
    10201 acggcccggt cgagcgccac ttccagatct ccgccatgaa gggtgaaggc acgcaggcgc
    10261 tgatcttcgc gatccaggac ctgctcgacg ccgagcgcga ccgcatcgag gccgagcgcg
    10321 ccgagcgcga ggctgccgag gccgcccgcc tggccgccgc ggacgccgag cgcgccgccg
    10381 ccgacgccgc ctacgagcgc gaggccctgc tcgatgcgga cgacgagctt cccgaggacg
    10441 agcccgacgc cgaagaggac gacgctcccc cgccgcgctg aacccatccc gcgtgccgcc
    10501 cggcgggcgg cgcgcacttc gcagcctttg ccgccccact ctctccgctg cccgcacgca
    10561 acccgatgag aaccaagctc cgcaacgccc gccgcctcgt ggtcaaggtc ggctccgccc
    10621 tcgtcaccaa caacggcgcc ggcctcgaca aggacgcgct cgacgcctgg gcgcgccaga
    10681 tcgccgcgct gcgcgccgag gggcgcgagg tcgcgctcgt gtcctcgggc gcgatcgccg
    10741 ccggcatgca gcgcctgggc tggacgaagc gccccaccga gatgagcaag ctgcaggccg
    10801 ccgccgcggt cggccagatg ggtctggtcg aggcctacga gaaggccttc tcgcgccacg
    10861 gcctgcacac cgcgcagatc ctgctcaccc acgaggacct ggccgaccgc aaccgctacc
    10921 tcaacgcgcg cagcacgctc accaccctgc tcgcgctcgg cgtggtgccg atcatcaacg
    10981 agaacgacac cgtggtcacc gacgagatca agttcggcga caacgacacc ctcggcgcgc
    11041 tcgtcgccaa cctgatcgag gccgaggccc tgatcatcct caccgaccag cagggcctgt
    11101 acaccgccga cccgcgcaag gacccggccg ccacgctgat cggcgagggc cgcgccgagg
    11161 accgccagta cgaggccatg gccggcggct cgggcagcgc gatcagcaag ggcggcatga
    11221 tcaccaagat ccgcgccgcc cagcgcgccg cgcgcagcgg cgcccacacc tgcatcgcca
    11281 gcggccgcga gcccgacccc atcctgcgcc tggccgcggg cgaggcgctc ggcaccctgc
    11341 tctacgccag cagcacgccg ctgcaggcgc gcaagcagtg gctggccgac cacctccagc
    11401 tcgccggcga cctggtcatc gacgacggcg cggtggcggc gctgaagagc ggcaagagcc
    11461 tgttgccggt gggggtggtc gaggtgcgcg gcgatttcga gcgcggcgcg gtggtggcct
    11521 gccgcaatat cgcgggcgag gaggtggcgc ggggtcttgt aaattactcc gcatcggaat
    11581 gccggcgcat cgcgcgccgg ccgaccgcgg agatcggaaa tctgctgggc tatgtcgacg
    11641 aaccggaagt ggtccaccgg gacaacatgg ttagccataa cgtcaggagc taggggtccg
    11701 cgcggcagaa cgctggagca gggcgcgccg ggttttccgg cccttcgtcc ttcacgccgc
    11761 gcgcagcgag cacatcctgc gcagattcag cgccataccg acgaacctcc agtccgcgtt
    11821 gccgcgctcc aggccccgca tgctgaactg tcgtaatccc aacacgttct tgatccagcc
    11881 gttgggcggc gcggcaatcc attttcgtcg cgcgtaggcc gccttacccg ccttgctgtc
    11941 gagtctgtcg gccatttttt tgccgtgcgt ggattgcgtt gccggtcgca gctcaacggg
    12001 tgctttccct cacggcccaa cgccaccagt tcggtgccgc agccgtccag gcccctgaac
    12061 gcctgctccg agcggttgcc ggtatcggca agcgccgggc gcggtcgctg ctccaagctc
    12121 gcgtgcacgg ccagcagccc ctcccccgga agctgtccgg cgtcgctggc gttattggtc
    12181 agttggaccg ccatgtgtcc gccgaagcct gcaggggggg gctgtcacac ggacggctcc
    12241 accgtgtcga acatggacag cgctcatggt ttcgtgcgtc aattcgacgt ctcgcgcatc
    12301 gttcggacct agaattaacg cagcaatggg gagactccgt gagaaaatgc aaaaaatgcc
    12361 tgctgccgga agcggctccg ggtgccgatc tcgattcttc gggggtgtgt gccgcatgcc
    12421 gggcgacccc tacccgccgg acaacgcagc cggacgccag tcggtatcgc gaggaccttg
    12481 aggcaagcct ggaggcggcg cgcaaccacg ccggttcgag ctacgactgt attgttccgc
    12541 tgagcggtgg gaaggatagc ctcttcctcc ttcaccgact caaggtcgag tatgggatgc
    12601 gtgttctggc cttcacctgc gacatcgacc tgcctccgat cgcatgggcc aatatccgcc
    12661 tggcgctgcg caagcttgat atcgaccatc tggtcttcac ccctgcccat gcgttcctca
    12721 ccaagttgtt ccgctacctg ctgaagaatc aggaagcacg cggagcggtg tattcagtgt
    12781 cctacgtcta tgcgccgctg ttcgagggcg cggcgatcag gctcgcgatc gagaagaaca
    12841 tcccgctcgt gctcgccggc tactcccccg gccagccaga gcccgagcgc atgctctacg
    12901 agttcgcccc cgcgctcgtc agtggcgagg attggacgcc gccacacctc aaggaatgcg
    12961 gcgagttctc cgcagacgaa ctcgaagcgt tctacaaccc gctgcgcttg ccggccggca
    13021 cacgattccc gcgctatatc gccccctatc acgcctggga gtacgatcag gatcaggtcg
    13081 tccgcaaggt caccgaactt ggactggtcc ggcgcagcac acatgcaagc ccgatcgtga
    13141 gcaactaccc gatcaactgg ctgatgatgt attccgatct gcacaatttc ggctacaacc
    13201 cctatgcgcc cgagttcgcc gcattgatcc gcgagggccg ggcgagtctg cgctattggc
    13261 gcgtgatggc tcccatcgtc gatctgatga tccggcacaa gatcggcctg ggccgcgagg
    13321 tgcggcgcag catgaagtgg ctcggcctgg atgatgcgga tctgcgcatc acgctgccgc
    13381 gcggcgcgta cgatcctccc atgctgcgtg ggggctgagc atcatggacg atgcgccact
    13441 gagccttttg gaccgtttgc gctcgcgcgc gctcgagacg ccgcaacata tcgcatacct
    13501 gtatcggcat ccgggcagca gcgagcgatg ggacaccttg agttggggtc aggtgcttgc
    13561 ccgggtggaa gccatgtcgg cggcgctcgc cgacctcggc cttcgcgatg gcgaccgtgc
    13621 cgcgatcatg atgccgacct cgccggattg ggagatctgc cagttcgccg ccatggccgt
    13681 cggctgtgcc gtgatcgggc tcgatctgca cgacgctcca cgcaacctgc gccacatcct
    13741 ggaggctacc cgcccacgga tcatcttcac caccgatcca ggccagctcg agcggattgc
    13801 agagtgctgg cacgcccccg agttggcggt catctcgagc ggcgaggcga agacctcggg
    13861 cacccacctc ctggcgaccc tgctcgccac cgcgagcgcg ctggagaaga gccggtcacc
    13921 gcagcccgat caggtggcca cgatcgtttt cacctcgggg agcacgggac agcccaaggg
    13981 catcgcctac acccatcgac agatcatctc agcctccgac ctgatcctcg agcgttttcc
    14041 ggacatccgt tcggatgcac ggctggtgtg ctggctgccg ctctccaacc tgttccagcg
    14101 catggtgaat ttctgcgcga tgcgccgcgg cgcggcgtcc tatttcatcg ctgatccgca
    14161 taccatcgcc agcgtgctgc cgcagaccga gcccaccttc ttcatcgggg taccacgttt
    14221 cttcgagaag ctgcatgcgg gcatcgtcag ggagatcgaa tcgaagcctt tgccgctccg
    14281 cgtgctgctc gagacctcct gggcaatcgg catgcgcgcc gcacgcgcac gccgggaacg
    14341 gcgttcggcg gacatgctga cgcgcgcctt gttgccactc gccgatcgcg tgctcgcccg
    14401 catccgggca gtcatggggc gtaatctcca attcatggtg agcggctccg cccccttgcc
    14461 ggtgtggctg gcagaacgcc tgcacggcct gggctggctg gtactcgaag cctacgggat
    14521 cagcgagaac gtcgcaccga tcgcaatgaa cacgccggat gacttccgct tcggcagcgt
    14581 ggggcacgtg ttgccgggca acgagctacg catcgccgat gacggcgaat tgctcgttcg
    14641 cggcccgtgc gttttcgggg gttactacga aggcaccgac gaaggttcgc cgattgacgc
    14701 cgagggcttc ctccacaccg gcgactatgc gcgcatcgac gatgcgggct acctgtggct
    14761 ggaggggcgc aagagcgatg tattcaagac ctccaccggc cgccgcattg caccggcacc
    14821 gatcgagggg gcactcagga gcatccccgg ggtcgagcat gccgtcgtga tcggacatga
    14881 tcgtccgtat ccggtggcga tcctcgcact cgccgcccat tcgctgcagg gagcaggcgg
    14941 cgagcgcgca gttctcgaac gaatcgctgc ggatgtggtg gcgacatgcg ggatctttcc
    15001 cccgtatcag cgtccagggg cgctgatcgt gacattccgt cccttctcca tcgagaccgg
    15061 cgaactgacc gccaacctca agatccggcg gcgacccgtc gagctcggtt tccgcacgca
    15121 gatcgatgag gcttattcac gcccggccag ccgcaccgag cgcggcgcga ccaccgcact
    15181 tcctgtgatc acctcgtcat gagcacttat tttctgaccg gcgcatccgg cgccgttggc
    15241 agcgccatcg tccctctgct gctggtcgac cctgccacga agctgaggat cctgctgcgt
    15301 gctcgcacgc cggctcatct ggaggagcgc ttccagtcgc tctgcgagtt ctggcgcatc
    15361 gccccggaga acgcagatcg cagacgcatc gagccgctgc gcggcgatgc ggctttgccg
    15421 cagttcggac tgtcggccgt ggactacgct cgggtttgcg aggacaccac ccatgtaatc
    15481 cattgtgccg ccagcgtccg catgaacgag acgctcgacg aggcccgcgc ctcggccatc
    15541 ggctcggcac gagaggtgct cacgcttgcc cgtgccctgc aggcgcgaag cctgctgaga
    15601 aaggtcgagt tcgtcagcac cgttggcatc gcagggaagc ggcagggggc gctgccggaa
    15661 cgctggatcg acgaagcgcg cgagttccat aacagctacg agcaatccaa ggcggaagcc
    15721 gagcagctcg ttcgccacgc gatcgacacc gagggcctgc cagtcacggt gcaccggccg
    15781 agcatggtga tcggcgactc gcgcgacggg cgcatcatcc atttccagat cttttatttc
    15841 atcgccgagt tcatgagtgg ccgcaagacc ttcggccttt acccggactt cggcgaggta
    15901 cgcctcgatg tgattcccgt ggattgggtg gcacgcgcca tcgtggacgc gagccgcagc
    15961 cccgaaaccg ccggcagcat cttccacctg tgctcgggtc ctcagcgctc accacgcctg
    16021 aacgagttgc gccccatcct gcgccaagcc ttccgcgacc acgggcatcg cctgccgcca
    16081 tgcttcaccg tgccgcatcg gctgttcgcc gccctgcccc gcatcggtgc gctggtcgcg
    16141 ccgccgcgaa tgcggcgggc cctgtccacc ctcccgatct atctcgacta cctggccgat
    16201 aaccagggct tcgacaaccg ggtcttcgtc gcacgactcg ccgagcgttc gcttcgcctg
    16261 cccgattggg gggagtacct tccggtggtg ctgtcctact atctgaaggc gaaatacggc
    16321 cctcgccaat cgccttgagc aagcagccgc caaagcggcg ccgacaccgg acctatgcgt
    16381 tcctgcgcag cgcatcgacc ggctgaattc gagcgacccg ccaggcgggc agcagggatg
    16441 cgagcacggt ggcgaccagt cccaccgaaa aactgctcgc aagcacgctg ggcaccaggc
    16501 ggatatgcgc cgtatagccc agattcgcgt tcgggggcgg tggcatttcg atcccgatcg
    16561 cggacagcac cagcgcactc acaccgccca gcgcgacgcc caagccgcca ccgatcatgc
    16621 cgagcaggac gttttcgacg atcaccagcc ggcggatgtc accgcgccgg ttgccgagcg
    16681 ccatcatcgt gccgaactcg cccacacgtt cgaatgcgct catgttcacg ctgttggcga
    16741 ctcccagcag cacgagcacg aggatgatca gttgcaggaa accgaactgc cgctcgtaca
    16801 gcgcaaccgt gttctcgtaa aaggagttca aggtacgcca ggtcagcaca gcgaaaccgc
    16861 tccctgccag gcctgagcgc aaggcctcag cggtcgactc ggtgagtggg gtctcacgca
    16921 gggaaatcac gaacgtattg actcccgcgg tgccgagcaa ctcctgcgca gcctcgagcg
    16981 aaatgctgac cgcgcgtaga tcgaaatcgg ccgagaagct ctggaacacc ccgacaacct
    17041 cgagttccag gctgttcagc gccccatcga gcgtattcgc aagcagcgtc acgtagtcgc
    17101 ccggttccag cttgagtgcc tgcgccacgc cctggccgag gaggacgccg tatcgatccg
    17161 ccgcgccgag ctggcggccg gctgtgatct tgagctggct cccgaggaca gcctccttgt
    17221 ctgcctccac gccctggccg acgatggccc aatccgaccg gccgttgttg atcagcccgg
    17281 agaagttgac ccgtgccatg acgtcctcga cgcccggccg ggccgcgagc aagccgcgca
    17341 ggccctcaga atcctcgatc acgtaacgct ccgggctacg cgcgccacgc tcctggaacc
    17401 cttccttcgc cacctggatg tgtcccgact gcgaatggat cagcgcctcg ccaagctggt
    17461 gatagacgtc gtgcacgaat ccaccgctga ggatcagcgc catcaccccg aaaacgatcg
    17521 ctgcgagcgt cattgcggtc cgcaagcgct gacggacgat gttgcggaat gcaagcctga
    17581 acatggtgcg gcagactcct agcggttatg acgaagggcg tccacgatct ccagccgcga
    17641 agccttccag gctgggtagg cactcgctgc gagcgtggtc acgagggcaa ggccaagcgc
    17701 ctgtaccaac agcgagacgg tcaccaggat ctcgccgcga tagctctcgg acatgccggg
    17761 cggcggcggc atggggatcc ccacccagga gatcgcgaat ccaccgacga cgccaaggat
    17821 tgcgcccatt gcggccccgg tgagaccaat ggtcagtccc tcgaacagga actgccgcaa
    17881 gatctggcgg cgggtccgtc cgatggccat gcaggtgccg atctccgccg tgcgctcaaa
    17941 aacgttcatc atcatgatgt tggagatgct gagcacgatg atgatgccga tgatggtctg
    18001 taccacgccc atctggcgtg acaacaggga aacgagcttg ctgtagaaat ccgccatctc
    18061 gtaccaggga acgaagacga ggccgctccc ggagtggccg gcgcgcaacg actccagcac
    18121 cgcgggggtc cgcgcggtat cgtcgagaac gaggatcagg cgatgcacat cctctgtccg
    18181 cagcaggcgt tgcgcgagcg cgagcggcat cctcgcggca gagtcatcgt aggccttgct
    18241 aacggtggtg aacaatcctg ccaccaccgc ctccaccgca ttcaggccgc cggcagccgt
    18301 gtttgcgagc aggacaaccc ggtcccccac ccgcactccg aggttctcgg ccaagccgcg
    18361 accaagcaga atcccttcgt ccgacgcacc cgacaggacg gagccttcgg ccacgatcat
    18421 cgccctgctg aggacacgct cggcctccgg atcgacgcct tccccaagga aggacagggt
    18481 gtgctcccca tggctgatca tgccgttgaa tgcaaggcgc ggtgcaatga ccttcagtcc
    18541 agggacggcc gcaagccggc caagctcggc gggtccgtcg tccaccagga actcgaaggg
    18601 atccgcctgg ccgtgttcga ggtagccgtc gcgaaccaca tgtacgtgcc cgagtccgtt
    18661 ctggatcgtg ccctcgcgtg tcgcccagaa gatccactcg acgaagcccg tcgccagcac
    18721 cagcgcgacc acaccaaagg cgaccgcgat caccccgaaa aggctgcgcc ggtattgccg
    18781 cgtgacgttg cgcgcggcgg cacgatactc ctggatgaga taggcgaacg cgccaggcag
    18841 cctcatttgc tcccccgata tgccaccgcc acgtcggtcc tccgcttgcg caagttcctc
    18901 atcttagcct gtcgcccacc ttgcctgcat gccctcccaa ggcagcacac cgaaagaaac
    18961 cccttggtct tgcccatgga gacagtccag ccagccagcc agccagccag ccgcagagtg
    19021 tcggtttttt ttacactcac cacgacaaaa cccaggatca ttttcaatcg gacacttttc
    19081 agaatctatt ttccttttat tttccgtgcc ttacccagga tcaacgatta gtggcacggc
    19141 gtttgcttat tgatgcatgg cccggcgaat gaatctcggg tgaactttga agctaatcga
    19201 cacaatgagg tcactcatga aactcaagac tctcgcagca gcggtcctgc tcgccggcat
    19261 ggctacgggc gcggctcagg cggccccctg ggttggcaat ttcaacacgt ccaacggtgc
    19321 gaccttcaac gacgggttgc tgctcaacat cgacggtttc gacatctact cgcagggttc
    19381 ggcggcgttc ttcgtcggtg gcacccagct ctctccgacc ggcagcacgc tggccgtcgg
    19441 tgatatcgtg accacctact accaaggcgt agtcagcgcg ttcaacaccg gtgtctcgtc
    19501 gcccaacctt gcgtgggcct cccagccggg tggtagctac cagctcaccg tcgccgccgt
    19561 gttcaacgag atcgtgactt ttgctacccc gggctttgca ctggttcagc ccatttccgg
    19621 cggtcgcgtt tccgtattct atgacgacgc cactctcagc aacagcttca tcacgagcac
    19681 ggctcaagtg ttggccggga ctggctacac tgacggcctg ttgatcgccg acggcagcgt
    19741 cagcggcgcc tcccttccga cctccttctc gaccaacgga actgaggcgg gtggcgttgc
    19801 caacctgaag ggccccctca ccttggctca ggccggttgg gacgatcctg ctaacctcgc
    19861 cgacgtcgtg ggtttcctgc ccacggttcc gagcgactac tcctcaagga ccacgctgca
    19921 gttcggtccg aacgaaggaa cctccttcca gaccaaaaac ttcttcgacg ctgccaacgg
    19981 ctggacgccg gtcgcctcga tcgctggccg gaccatccgt gccgacgcga acgtgaacct
    20041 cattcccgaa cccgccacgc tggccctgct cggcctcggc ttgttcggtg ccggcttggc
    20101 tcgccgccgc aaggcttgag tccggttcga agcgcatcag aaagaggcct gcgggcctct
    20161 ttctttttct gcaggctaga atcgctacat gaagactgat gcccgggatt tcctgctttc
    20221 cacgctgttg atcggactca atctggcagc gtccgcattc gcgctatccc tatgctggcc
    20281 cctcgtcacg acgctggccg gatctttcgc acaggtggtc ggcgctttgc tggcaccagc
    20341 gacctatggg ctgtgcacgg ccgcttctct ggcgctgcta ggacgctttc atccgctgcg
    20401 cgagggtgaa tatgacctcg cacacgaaca gttcacccag tggaaagtgc ggcatgttgt
    20461 cgccgaactc ggcaaactgg cgttgtcact ctattttccg gtcttcgcac gtgcggcctt
    20521 ctatgccttg ttcggcaccc gggtggggcg ccaggtggca gtggcgggca agatcctcga
    20581 tccggggctc accgtcctcg aggaaggctg cgttctcggt gagggttgta tcgtcacctc
    20641 gcacacaatg tggggcgagc gcttcgttat gcgtgaagta catgtcggtg cgaacgcgac
    20701 cgtcggggtg ggctgcatcc tgatgcccgg ggtgcgcgtt ggcagccgtg ccgtactgct
    20761 cccaggatcg gtcgtcaaga ccggtaccgt gatcggcagt ggcgagatct gggggggcgt
    20821 cccagcatcc cgcctcaagg gccccggcga ccacgcctga gtcatcacgg ccggctcagc
    20881 tcgcagccgc tcggcgttcg ctttcgacgc gttcccggag ggcttcgtta acctgcacga
    20941 aaccgcgcag cacgttgtcg cgcaaccacg gggcaaacag cggcacgagc aatccggaaa
    21001 atgtttctcg ctgcctcacg accaccccgc cgcttgcgcg tggctccagt tcgaagcggt
    21061 ggagtccgtc catcagacca cgcacgccga aatgcccgag ccaggcaaag ctcttcccgg
    21121 cctcgacttc ggtcacccga agccggtagc gatcgcgctt gaggccgggc cactcgatca
    21181 ggacgagcaa ttcaccaccg acgacggctt cgccagcggc ctccggaagg gctggattcc
    21241 actcggcata gcgatcgacg cgaaccagga tctcccagac gctttcgacc ggggcatcga
    21301 cgaacacttc ggtctcgagg cgcagacaga agaatccctc gcggaagacc cgtggcgacg
    21361 cattgcctgc aagcatccct tgcatcctcg tcaaacctcc gcgtgattcc gggtcagcat
    21421 gtgttccgcc acgcgcagtg cgttcgccgc aatcgtcaag gcgggattgg ttccgccact
    21481 cgagggaaag aacgaggcat cgaccacata cagattggcg actccgtgcg cgcggttgtt
    21541 gcgatcgagc acactgcttg ccggatcgtc accgaagcgg caggtcccgc acacgtgcgc
    21601 gagcattcgg ttcttctccg cctgccggag cgggagaaat cgatagggtt tcagcgcgcg
    21661 cgcaatgcct tgccggaaga gccgcaggcg ggctcgatcg ggctcgcgca ggacgtaatg
    21721 aacccgtggt ggatcgcccg cctcgatacg gttgtcgggg taaggaagat cctccatgat
    21781 ccctgccagc agcactcccc gtcggaacaa ggccgccaga ccgcgttcaa gcagcggtcg
    21841 catcgccttc gccacgacgc cagcgaacgg cagcgcagcg gacgcatcgg cgatcacctc
    21901 cgtggccagc atcgaagcgg gcggcaaggc gccaaaggac tgcagggtgc cgagcttttc
    21961 tcctgcgcca acatagaaat cgctcagccc gatctccttg gaccgcggat cgccccgcgc
    22021 gcgcgtgaag accaggtaga gatcgacgcc atgacgcatg aggttgcgtc caaccagtcc
    22081 ggaacggttc gcgagcccgt cgggccagcc cggtgagcgc gacgaaagca acaggcacgg
    22141 ggtcgccagc gcacctgcac cgagggcgta atgcctggca cggacacgga actccgtccc
    22201 gtgccgccga cacacgaggg cggtgatgcg atcgcccgcc gcctcgagcg tgatcgcctc
    22261 gcactcgtcc agcaataccg caccgtgctc acggacggcc ggcctcaggc agctacgcgc
    22321 tgcatcgttc ttgcaatcgc gcgcgcaaag aaaaccctga cagcaggcgc aatcgttcac
    22381 aaactcgcat gcgagcggca aacgataagg atgcagaccc gcggcagcga aatgcctggc
    22441 cagttccgca ttgtgcggcc ccggaactgg ggcggcgggc aaggcctcgt cggctgggcg
    22501 cagcgggtcg cgcgcgccgc gcacgcgata cagtcgctcg gcgcgacggt agaagggaag
    22561 catctcctcg taggaaaccg gccacgcatc cggcagcgag gagccgccgg ccagcgcatg
    22621 caaacggggg ccagggcgaa agtcctccgg gaagaaccgc tccattgcca tgccgaagag
    22681 cgcgctgctg ccgccccccc cgcagcccaa caagggaacg aagccgccgc cccccgagag
    22741 gacctcttcg ctccagcgcc ctccttggcg caacaaggcc tggtggcggg gagcggcaag
    22801 cgcagcctcc tcgaaatgcg tctcgggata gaaaccgcgc aacccgtccg agggttcgag
    22861 acccgcccgc cccttctcga cgaacagcac cctctgccca gcagccgcca aggcatgacc
    22921 cagggtcgcg ccccccacgc cggtgccgac caccacgcag tcccaaaccc gatccgtcac
    22981 cgccgcgaga tcatccacgg agcacctcgt ccaccactgc cgtcagtcgt gccaccggat
    23041 cgtagcctgc gatgctacgc cccatctcgc gcgcgcgcag atgaatggcg gaatcatcca
    23101 gcaggtcccg gacccgcgca cgcagaccag ctatcgacaa cgagtcgctt ctcacgcaga
    23161 ctccaactcc agccgattcg acgtagctca tgctcaactg ttgatccatg tgcgcagcga
    23221 tgccgagtac cggcttgccc tcggcgaggg cctggtagac cgtcaggctg ccaccgttac
    23281 agatcatcag atccgcgcgt gctgcgagac gctcgcccgg ggcaaaatcg accagccttg
    23341 cattgctcgg tacgctccgg gggatggcct tgcccgcggt ggttaccatg accagcacat
    23401 cgaggccggc gagtgcctgc aacaccacgt cgagcaattc cgctcgcccg gaacttccca
    23461 gcgtgacgta gaccagcggc cggtcgtcgg ggagtgcatc ccaccactcg ggcaggggaa
    23521 cggcgggcga ccacgacacc ggcccaatat acgtgtgcga ggggggcagg tcgaccgtcg
    23581 gcacaagttc cgctgcatcc acgtagagag tccgatcggc atcggcgtag acgctgaacc
    23641 agtcattgcc cagtccggcg agtccgtgct cggcccgcac acggttgagc ggcctgcact
    23701 ggagtgccga ggccaccggc cacaccgcgc ggaacagcca ggctgcgagt gccgacggca
    23761 gcacacgacc aatgggcagc tcaggcatgg gcaggcgacg cgtcggcgta taggggctcc
    23821 aatacgcgtt gaccagcgac agataaggca cgccagccag ccgcgcgctc acggacagcg
    23881 agaggcggtg atcgccaacc accacgtcgg gacgcaagcc ctccagaagc gcaaggtccg
    23941 cagccacgta agcgcgcagc gtggccgcat cgtaaagggg ccgcccacgc gccacattgt
    24001 ccaggaaacg atcactcggc atcgtctcga gctcatgcag tgcgcaggac aatggcccga
    24061 gaaagcgcgc aaaacgagga tccgcagcca gatgcacctc gaagcgctcg ggatcgatcg
    24121 cccgcgcgag cgcgaccgga cgagcgagat gcgcgagcgt gaccgcgtcc gcgacgaata
    24181 gcacgcgcgg acgccgtctt tcccgcgcga cgtcggtgac ggcgatcacg cctgtccgcc
    24241 cgtatccggc gtggtcgggt ggcgcgcttc acgctcgctg gtacccacgc cgtaatggcc
    24301 cggcgcgagg atgttcgctg gatcgagcgc agccttgatg cgatcgttca ggcgcttgag
    24361 ctccggcgca tcgtcatgaa gcgtgtccca cgcggcgagt cccgcgcgat actgctcgta
    24421 gcatcgtttg cacatgtgat cgagcagcgc tgcatagagt tgcctgctgc gctcaacctc
    24481 gtcgggatcc tcccgatcgt agatgattgc catcaggcag atcatcgagc ggggattcat
    24541 cagcagcatc gcaacgtagt aatcgaagcc gtgggcggca aacagggcct tggtatcgct
    24601 cacgtagggc cacagatgcg cattcgtgaa cgggagaatc ggagcgaacc agatcagccc
    24661 gcaattgtct cgcgccgggt gcacggcccc gacgggcggc ggccggcgcg cccggtagta
    24721 ggcatgcttg acgaaatact cggtgggaac accacgctgg atcttatgca cgaagggcgc
    24781 cgactcgagc acagggagcg aggtgccggc cagtctttgc gtcatccctc gcaaggcttc
    24841 gctcttccac gcccacctga caatgcgttc gatccaggga atctgccagt cagccacgaa
    24901 aatcagccgg ccgtaagggg cgagcgcctt gcggatcagt ctgcgctgct ctcgcaccag
    24961 gctgcgagtc ccgtaaatcg caccagcgca actccatggc gcgacaccgt acttgctacg
    25021 cagcatgccc aagtctgcat cggtgagcgc cccgccctgc ggcactggct cggcgatccg
    25081 ctgcgtcagg atcgtgagcg agacgaaatc gttgatcagg tgcatcttcg tcgtgacgac
    25141 gcccccgagg gcgagcttgc ggtacgcatc gacgactgca ggcatgtggg actcgtcaga
    25201 gacttgaaaa acgaaggact catgacactc cggcgccggc atcaaccaga tcccggccct
    25261 ggtcaccacg cccagattcg actgggtgaa caagccctcg agataaggac cgacgcccca
    25321 cttatgggta tgccaggtgt gaaggccctc tcgcgtgctt ccggtgcgga ccacctcgcc
    25381 gtccgcgagc acgacttcca gcccgcagag gttgccgaaa tgatcgccgt acggcgtctc
    25441 gcccacacca cgctcgatcg cgttgccgat cacgctgccc tgcgcagtgc cgtcgatgca
    25501 gtcgatccac agcttgtggc cgtgctcggc aagatgggcg ttgaactgtt cataggtcac
    25561 gcccggttcg atgacggcgt aggcaagttc ctcattgacc tcgaggatgc gattcatccg
    25621 ctcgaggatc ataaccatcg cgccgtcggt gcaggcgagt gtcgtcgcgt aaccccagtt
    25681 gcgccccttg ctggacggcc acacgggtat gccgtggcgc gcggcgatcc gcatggtggc
    25741 agcgacctcc tcggtcgagg ctggaaaaac gactaccgcg cactcggtgc gccaggggat
    25801 ggtgcagcga gaatattggt ctagcgcttc aggcgtggtg agcacgtgtt cggcgccgag
    25861 caccgcattc aactcggcca gcacgccgac gggcaagcgc cctgaacggt tccttgattc
    25921 catcggacga tttcccgaga tcggacgaaa tgaaggattt cactctaccc caagtacatg
    25981 cactgcggaa cggtctgcgc tgccgcgaga accaccctgc cggagcgcgg aaccgccgac
    26041 tctgctcggc acattggagg tgaatcgaat atcatccata agcaagccgg cacactcgcc
    26101 ggtccggtca aatcacgctg gcaaccatcg acatgtcgct cttcgggctt ttcaatctgg
    26161 gcaagggctt tcgtgagcac ttccgcatcg acgcagcgct ggacgacacg ctccgcgaag
    26221 acgtctatcg catccggcac gaggtctatt gcgaggaact ccggttcgag ccggagcgcg
    26281 ccgaccgacg ggaaatcgac acgtttgatg cacatagcct gcactgcctg ctacggcgag
    26341 tcgctgaacc gcatactctg gtcggatgcg cccgcctcgt gctgaccgat ccgaaggatc
    26401 cggatgcgcc cctgccgttc gagcgcactt gcgcgggcgc actcgatcca cgcatcgtcg
    26461 atacggccgc actgcggcgc gaccggatcg cagaggtgtc acgactggct gtgcgggcac
    26521 cattccggcg acgcaagggc gaagaccgtg tcgcagccag catcagcaac gaggacttcg
    26581 gaagcgcaac acagccgcgt ttcccttata tcccgatcgg actgtatctc ggggcgatct
    26641 cgctggcggt ccacaaggac atcgaaaccc tcttcgtcct cacggaacca cggctggcaa
    26701 gtcatttctc caagctgggc gtcgatatcc gccagatcgg cgcaccgata tcccatcgcg
    26761 gtgtccgcgt cccatcgatg atggatgtcg acagcatcat ccgcaacatg cgctccctca
    26821 tgcgtccgtt ctggcgggca gtacacgagg aaatcggccg cggcttcgaa aagccctgat
    26881 cgggacaggg gcggccagga ttcctgaccg atcccctacc acaccacccg gcatgccggt
    26941 ccgcaccggg cgatccgaag ggtgcgccca tgctgggcgc acaaaaaagg ggccgcagcg
    27001 taccgcggcc ccctcgcggg agtccgccat gccggcagtc ccgcggaagc tggtgaacaa
    27061 tcagcccttc agcgccacct tgatctgctc gagcgtgctc ggatcgtcga tcgtggtcag
    27121 gtcgcccgca tcgcggcctt cggccagcgc ctggatcgag cgccgcagca tcttgcccga
    27181 gcgcgtcttg ggcaggccgt tgatgaagtg cacacgggcc ggacgcgcga tcgcgccgag
    27241 gctctcgtcg accttcttca tgacctcctt ctcgagcgcg gcgcgcttct cgggggtgtc
    27301 gacgtcggcg gcgttcttga ccaccgcaaa ggccatcggc atctggccct tgagctcgtc
    27361 ggccacaccc accaccgcca cctcggcgat cgccgggtgg gtctgcacgg cctcctcgat
    27421 ctcgcgcgtg ccgaggcggt ggccggcgac gttgatgacg tcgtccatgc ggccgaggat
    27481 ggtgaagtag cccttgtcgt ccttgatgcc ccagtcggac gaggaataca ccaccggctc
    27541 ggtgaacagc gtgaagtagg tgctgacgaa gcgctcgtcc tggccccaca cggtcgacag
    27601 gcagcccggc ggcagcggcg gcaggatgcc gacgatgccc ttctcgttgg cgccgcactc
    27661 ggtgccgtcc tcgcggaaga tgcgcaggtc gtagccatac accgggaagg cgggcgagcc
    27721 gagcttgatc gggctgtcct cgacgccgcg gcagatggcg agcatcggcc agccggtctc
    27781 ggtctgccag tagttgtcga tgaccgggat gccgagctct tccatgatcc actggtggct
    27841 ggtctcgtcc agcggctcgc cggccaggaa caggtgcttg agcgaggaca ggtcgtactt
    27901 cttgaggaag gccgggtcct gcttcttgag cacgcgcacc gcggtgggcg cagagaacat
    27961 caccgtgacc ctgtacttct cgacgatctg ccaccagatg ccggcgtcgg ggcgcagcgg
    28021 cgtgccctcg tacatgatcg tggccatgcc ggcgagcagc gggccgtaga tgatgtagct
    28081 gtggccgacc acccagccga tgtccgaggt cgagaacatg gtctcgcccg caccgccggt
    28141 gaagatgtgc ttcatcgacg cggtcagggc cacggtgtag ccgccggtgt cgcgctgcac
    28201 gcccttgggc ttgccggtgg tgccggaggt gtacaggatg tagctcggtt cggaggactc
    28261 cagccacacg accgggacct gggcgtccat gtgcctggcg cgcagctcgg cgtaatcgac
    28321 gtcacgccct gcgaccttgg cgaagccctt gtcgaggccg cgatcgacga tcagcacctt
    28381 ggcgggcggg aactccgcga gcttgcaggc ctcgtccacc aggtgcttgt agggcaccgg
    28441 cttgccgttg cgcatgccag cgtccgagct gaccatcagc accggcttgg cgtcgtcgat
    28501 gcgggtggcg agcgagccgg ccgcgaagcc gccgaacacc accgagtgga tggcgccgat
    28561 gcgcgcgcag gcgagcatgg cgaacgcggc ctcggcgatc atcggcatgt agatcagcac
    28621 gcggtcgccg cgctggacgc cgagttcctg gtagatcgcc gccatgcgct cgacctcgcg
    28681 ctgcagctcg gcgaaggaat acaccttctc ctcgtcggtc tcggtcgaga tgtacaccag
    28741 cgcgcggtcg ttcgggcgcg tggcggcgtg gcgatcgacg gcgttgtagc acaggttggt
    28801 ctcgccgccc ttgaaccact tgacgaacgg cggcttggaa tagtcgcaga cctgctctgc
    28861 gggcttgttc caatgcacga gctgggcctg ttcggcccag aacccgtcgc ggtcttcgat
    28921 ggaacggcgg tggaactgct ggtaatcggt cattgcttcc tctcccgtct gccttcaatg
    28981 atcgtgttgt tgcacgcgac gtgtgcgggc ccctcggcgc cgggacagcg cctcgaaacc
    29041 cgcttgcaca ccccttttcg gacggccccg cagctgcggc cgccgtccgc tcatccgccc
    29101 ccgcccttgt cgtggaactc gcggagtctt gcgagcggta gtccggattg aagcctggat
    29161 tctagcaatt cgagcagcgg cagcagcgcg ccgacgagcg cgggcagctg cccggcgacc
    29221 tcgtcgcgcg cgccagcgcg cagcaggcgc agcgcgccat cgacgctggg gatgcgcgcg
    29281 agctcgcgct cgatcgccgc cgggtcgacc acgccgccct cggcgacgac gcggttgcca
    29341 cccgccgcac gcgcctggtc ggcgcgctcc tgggcgagcg cgagcagcgc gccgatcgcc
    29401 tcgcgaccgt cggcgaccgc gctggcgacg ccgatgctca gcgtcacgcg gatgcgctcg
    29461 tcgcggtagg ccatcaccag cttctcgacg ccttcgcgca ggcgcagcgc gaaggcgcag
    29521 gtggacacgc ggtcgatgcc cggcgacagc agcgcgaagc aggcctggcc gtgctgcgac
    29581 aaggtgtcct cggcgcggat gcgcccgctc accagcttgc cgagcttgcg caggatcagc
    29641 tgcacgacct gcacgccgta gcgcgcggcg agctcgtcga actggtcgat gccgatcacc
    29701 atcgcgccga tgtcggcctg gcgccggcgc gcctcggcca ctgcctgggc gccgtggtgc
    29761 tcgaggtagg cctcggtcgc gagccccgac tcggggtcga ccgggctctg gcgctcgagc
    29821 gcggcgcggc tgcgctcgag ctcgccctgt gccttggaca ggcgcagcag cgacatcagc
    29881 gtggcgagca gctcgacccc gcccgtgccc ttggtgacga agccgttggc accgagggcg
    29941 agcgcgcgtt cgcgcgcgga ctcgtcctcg tcgccggaga tgatcaccac cggcaggtcg
    30001 cgcacccgtg gcagcttcga ggcgcgcagg cgctcgagca ggccgtagcc gtccagacgc
    30061 ggcatgccga tgtcggtcag cacgatctcg atcgccggat cgaccagcag cgcctcccac
    30121 gcggcctcgc cgtcgggctc ctcgcgcgcc tcgaagcggc cgcggatatg cttgacgatg
    30181 gacgcgcgca ccatgcgcga gtcgtccacg acgaggatgc gcggcagcct gccttccgcg
    30241 tcggtcgtcg gcgcctggtc catggcagcg ggctcaggcg ccgatgcgca cgacggtgcg
    30301 gcccttgacg cggccgtgga tgaagtcgtc gaaggcgccc ggcagcgcgt cgaagtcgat
    30361 cgtgcgcgtg atggcagcga ggtggcgcgg cttgaggtcg gtcgccaggc ggtcccaaac
    30421 ccgctggcgg gtcggaaagc ccatgtagcc cgaatccacc ccgagcaggc tcacgccgcg
    30481 caggatgaac gggaacacgg tggtgtcgat gttgaagctc gccgcgttgc cgatgctggc
    30541 caccgtgccg gcctgcttca tggtcgccag cacccagtgc aggatctgcc cgccgacgtt
    30601 gtccaccgcg ccggcccagc gcgccgcctc gagcggccgc accttgtcga agtcgatcga
    30661 cgagcgcagc aggatctcgg ccgcgcccag catcttcaga tagtcggcct cggcctcctt
    30721 gccggtgagc gcgaccacgt ggtaaccaag ctgcgccagc atgtcgatgg cgagcgcgcc
    30781 gacgccgccg gtggcgccgg tgaccaccac cggcccgttg gccggcgcca ggccgttgtc
    30841 ttccatgcgc acgatgccga gcgcggcggt gaagccggcg gtgcccagcg ccatggcctc
    30901 gaagaggtcc agcccggctg gcagcggcac cacccagccc gccggcacgc gcgcgtactc
    30961 ggcaaagccg ccatggtggg ctacgccgat gtcgaagctg gtggcgatga ccttgtcgcc
    31021 cggctggaag cgcgcatcgg cgctgccgac cacctcgccg cacaggtcga tgccgccgac
    31081 gcaggggaag cggcggatga tcttgcccgc gccggtcgcg gcgagcgcgt ccttgtagtt
    31141 gatgctggag tagtgcacgc ggatcgtcac ctcgcccgcg tcgagctggt cgacactcat
    31201 cgtgcgcatg ccggcgacca ccttgcggtt ctcgtcctgg tcgatcacga aggccttgaa
    31261 gggattcatc cgggagtctc ctgtcgatgt ggcgtgcagc cctgcggccg cgctgattca
    31321 taattatagc tgcaactcgg aatctgcccg aacaccgttc gccgcctcaa gttcgcgccg
    31381 cggcagccgt caatccggat tgatcccgtg cgccgcaccg ctgccacacc gaccgcgcca
    31441 gagaccgcga ccatgcccct gctgcccagc cccctgccct cgtccgcagc ctacatcgac
    31501 gccttcagcc gcgccgggct gcccgtcctg cgccacaccg cgcgcgcctt cgaggagttg
    31561 cgcggcgccg aacacccgcc cggcgcgcgc gagatcgccg cggtggtgct cgccgatccg
    31621 ctgatgaccc tgcgcctgct cacgcatctc gagtcgaacc ggcgcgcctc gcagaaccac
    31681 gacatcacca ccatcgagcg cgcggtgctg atgctgggcg tggagccctt cttcaccgcc
    31741 ttctccgcgc tgcccacggt ggaggacacc ctcgcggcgc atcccaaggc gctcgtcgtg
    31801 gtgctcaagc tgatcgcgcg cgcacgccgt gcggccacgc tcgcgcgcga gttcgcgacc
    31861 atgcggcgcg atcacgaggt gcaggagatc accgtggcca ccctgctgcg cgaggccacc
    31921 gagatcgtgt gcgcgatcca tgcgccgacg ctcaccctgg aggcgatcgc gcgccggcag
    31981 gccgatcccg cgcggcccgc ggccgaggtg cagcgcgagg tcttcggcgt cagcgccgcg
    32041 gagctgcagc acgcgctgat cgccgcgtgg cggttgccgg gcctgctcgc cgggctgctc
    32101 gacagcgacc acgccgacaa cccgcgcgtg cgcaccatca cgctcgccac ccgcttcgcc
    32161 cgccaccagg cgcgcggctg gaccagcccg gcgctgcagg acgacctggc cgagctcgag
    32221 gcgctgctgc accagccgcg cgagagcctg ctgcagcgcc tgggcgtgcc ggccgatctg
    32281 cgtgccggcc tgctgccgga cacgcaggcg gagtgagcgg agcgcaccgc agcccggcgg
    32341 ctcgcggcca gccccttcag ccgcagagca ggatcaggtt gctgaagtcg agcagcagcg
    32401 ccggctgctg gtaggcggcg aagagcaggc cgagcacgat cgccgccagc acgaccagcg
    32461 ccaggcgcag cagcgctttc ttcatcgcgc agccagccga gcgagcggag cctcgcgcac
    32521 cggcagcgac agcgccgccg ccatcaccga gagcgcgatc gacagccacc acgccatttc
    32581 gtacgagccg ctgaggtcga agatgcgtcc gcccagccag gcgcccagga agccgccgat
    32641 ctggtggccg aggaagacga tgccgtacag catgccgacg tagcgcatgc cgaagatgca
    32701 gcccaccagg ccgctggtga gcggcaccgt gcccagccac agcaggccca tcaccgcggc
    32761 gaagacgtag agcgtgagcg ggctgagcgg gaacagcatc agcgccagga tggccacgat
    32821 gcgcagcgcg tagatccacg ccagcagcca cttcttgctg tacaggccgc ccagccagcc
    32881 cgacaggaag gagccgaaga tgttgaacag cccgatcatc gccaccgcgc tcatgccgat
    32941 attggccgac aggcccatgt cgaccacgta ggccggcagg tgcagcatca cgaaggcggt
    33001 ctggaagccg cacacgaaga agctccagaa caggaagtgg aagctcggcg tacgcatcgc
    33061 ctcggcgagc gcctggcgca gcgactgctc gacgccaccg ccgcgcgcgc tggtgccggt
    33121 gaccgcggcg gaaagcggaa tgatgaaggc aatgcccagc gccatccaca gcagcgcatc
    33181 ctgccagccg acggcggtga tcagcccctg cccgaccggc agcaccgcga actggccgaa
    33241 gctgccgccg gccgaggcga tgccgagcgc gaggctgcgc ttctccggcg cggccatgcg
    33301 cccgatcacc cccagcacca cgctgaaggt ggtgcccgac aggcccatcc cgatcagcag
    33361 gccggcgccg aggttgagcc cgagcgcgct gtcggcatag gccatgacca cgaggccgag
    33421 gacgtacagc accgccccgc ccgccagggt gcggccggcg ccgtggcggt cggcgaaggc
    33481 gccggcgaag ggctggaaca cgccccacag caggttctgc agcgcgatcg agaaggagaa
    33541 cagctcgcgc gaccagccgt ggtcgagcgt catcggctgc aggaagaggc cgccggtgtg
    33601 gcgcacgccc atggccaggg tgaggatcag cgccccgcag gccatgacga ccgcggggcg
    33661 gcgcaggaag gcgggggccg cgagggggga agacgggagg gacaagatgg gatttccgct
    33721 gcaagggagg cgattcgccg ccaccgtggc atgcgcaaca ggtggcgcga ggccgcgagt
    33781 ataagatgcg cgcattcgca acggagaccc cgaaatgagc atcggcagcg cagtcctcct
    33841 cggcctcgtc gtcctcgcgc tggtgtacgg cgtggtgatc tacaacggcc tcgtgcagct
    33901 caagcacaac ctcgccaagg cctgggccaa catcgacgtg ctgctcaagc agcgccacga
    33961 cgagctgccc aagctggtcg aggtgtgccg gcagtacaag cagttcgagc aggacaccct
    34021 ggcgcgcgtg accgaggcgc gcgcccgcgt cgcccaggcc cgcgaggccc gcgacgtggc
    34081 cgcgctcggc gccgccgaga acctgctgcg cggcggcctg gggcagctct tcgcggtcgc
    34141 cgaggcctac cccgagctgc gtgccaacga gcacttcatg cagctgcaga gccgcatcac
    34201 cgcgctcgag aacgccatcg ccgaccgccg cgagtggtac aacgaggcag tcaatgtgca
    34261 caacgtacgc atcgagcagc tccccgacct gctgatcgcg cgcccgctcg gctacgccga
    34321 gcagccgctg ctgcagttca gcgtcgccga gaaggcggat gtggatctga aggccctctt
    34381 cggcagctga gcgcgcgcgg cggggcgcgc gcggcatcgc gtgcgaggcg ggccggctcg
    34441 gaggcacggc agcagccggt gggcgatcac cccgcaggcc tcgccccctc ccccggcgca
    34501 ttcgacccca ccagccatcc catcatgctc gtccaccttc gtcacctgcg ggcagacctc
    34561 gccttgccgg ccatccagct cggcgcgatt gcgctcgcgc tgcgcctcgg ccccgggccg
    34621 ggcagcctgg ccgcgctcgc ggtgctgctc ggcagcggcc tgttcggcac cctgcgcgcg
    34681 ctgcgccacg cccgcctgat cgccgacacc ccgaccgcgc gcgtcgcctc ggcggcgcag
    34741 ggctacaccg agctgcaggg ccgcggcgcg gcgctcgccg gcgacccgtt gctgtcgccg
    34801 gccaatgcgc tgccagtgct gtggtaccgc ctgcgcatcg agcgccgcca gcgcgacggc
    34861 aagtggcggt tggtgagcgc cgacaccagc gacgcatcct tcctgctcga cgacggcagc
    34921 gcgcgctgcg tggtcgatcc ggagggcgcc gagatgctgg tgcggcgatg cgacgtgttc
    34981 gtccgcgacg acttgcgcta cacgcagtgg tcgctgatcg agcacgacaa gctatatgtg
    35041 atcggcgact tcgccaccct gggcagcgcc gaggtgcgca ccgacaccgc ggctgaggtg
    35101 cgcgagctgc tcgccgtctg gaaggccgac cgccccgccc tgctgcagcg tttcgacctc
    35161 gacggcgacg gcgagatcgg cctgcgcgag tgggaacacg cccgcgccca ggcgcgccgc
    35221 gaggtgcgcc agcgccaggc cgaggcgctc gccgcgcccg agctgcacct gatgcgccgg
    35281 ccgagcgacg gccgcctgta cctgatctcg gatctcgccc ccgagcgcat cggccgccag
    35341 taccgctggc tcgccgcctt ccacgccgca gtgttcctgg gcgccagcgc ggcgaccgct
    35401 tggttcgcgc agatcggggt gttctgacgc cggactcagc cggcgcttgc cggaccgccc
    35461 cattcgcggc tcccgccgct cctacacgac aatcgaagcc gcgccggttc tccattcgcg
    35521 gctgccgccg ctcctacatg aaaatcgaag ccgcgnnnnn nnnnnnnnnn nnnnnnnnnn
    35581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    35641 nnnnnnnnnn nnnnnttctc cattcgcggc tgccgccgct cctacacgac gatcggagcc
    35701 gcgccggctc ctgtaggagc gccggcaggc gcgaatgcgg cctggccatc acgcgaccac
    35761 gccggcggcg cgcgctgcag cgccaaattc gcggctgccg ccgctcctac acaaaaatcc
    35821 acgccgtgcc gcctcctcat tcgcggctgc cgccgctcct gcacgacaat caaagccgcg
    35881 ccggttctcc attcgcggct gccgccgctc ccgcacgacg atcgaagccg cggcggtttg
    35941 tgtaggagcg ccggcaggcg cgaacatcgc ttagcccgcg gcgcgcgact cgagcgcttc
    36001 ccagcgcagc atcgcggcat cgatctcgcc gtcgagcgcc tcgagccggg ccttgatctg
    36061 tgcgacctcc tgcggggcgt tctggtacag cgccgggtcg gccatgcgcg cgtgcagcgc
    36121 ggcctgctcg tcctcgagcg cggcgatgcg ctcgggcaag gcctcgagct cgcgcttctc
    36181 gttaaaggac agcctggtgg ggcgactcgc cgccttgggc tcggcggcgc gcgccttgtc
    36241 cgggggcggg acgctgcgcc tggcgctctc gcgcgccgtc gcctcgcgcg cggcggcctc
    36301 ctcggcacgc cggacctgca cgcgctgcca gtcgccgtag ccgccggcgt actcgcccca
    36361 gcgcccgtcg ccttcggcgg cgatcacctg ggtgacgacg ttgtcgagga acgcgcggtc
    36421 gtggctgacc aggaagagcg tgccgtcgta gccggcgagc agctcctcga gcaggtcgag
    36481 ggtctcgatg tcgagatcgt tggtgggctc gtccagcacc agcacgttgg ccgggcgcgc
    36541 gaacaggcgc gccagcagca agcggttgcg ctcgccgccg gagagcgact tgaccggcga
    36601 gcgtgcgcgc tgcggcgcga acaggaagtc gccgaggtaa ccgatgacgt gcttcttctc
    36661 gccaccgatc tcgacgtagt ccgagcccgg gctgatgacc tcggtgagcg gcagctcggg
    36721 gtcgagctgg gcgcgcagct ggtcgaagta ggccacggtc tggcgggtgc cgcggcgcac
    36781 cgtgccctcg tcgggctcga cctcgccgag gatgagcttc aacagcgtgg tcttgccggc
    36841 gccgttgggg ccgatgaagc cgatgcggtc gccgcgcagg atgcgggtgg agaagtcgcg
    36901 caccaccacc ttgtcgccgt agcgcttgga gacatgggtg agctcggcca ccatctgccc
    36961 gctcttgtcg ccggtatcca ccgccaggct gacgtcgccg aggcggtcgc ggcgcgcggc
    37021 gcgctcgcgg cgcagggact cgagccggcg cacgcgacct tcgttgcggg tgcggcgggc
    37081 ctcgacaccc ttgcggatcc acacctcttc ctgcgcgagg aacttgtcga agcgcgcggc
    37141 ggccttctcc tcggcctcga gttcctcggc cttgcggcgc tggtagtcgg agaagcgacc
    37201 ggggtaactc gccagcttgc cgcggtcgag ctcgatgatg cgggtggcga cgctgtcgag
    37261 gaagatgcga tcgtgcgtga tgacgatgac cgcgccgcgg aagtcgcgga tcagcccctc
    37321 cagccacagg atgccgtcga ggtcgaggtg gttggtgggc tcgtcgagca gcagcaggtc
    37381 gggctcggcc accagcgcgc gcgccagcgc cacgcgcttg acgccaccgc ccgacaggct
    37441 ggaaaccttt gccgccgggt cgagtccgag acgctccacg acctgctcga cacgctggtt
    37501 cagccgccag gcgccggcag cctcgaccgc gtgctggagg ccgtccagcc tggccagcgc
    37561 cgcggggctg gcctgctcgg cgacctccag catggcggcg tggtagtcga ccaaaaggcg
    37621 ggcggcggcg cccaggccgt cggcgatggt ctcgaagaca tcgcgctcga gctcgaaatc
    37681 gggctcctgc ggtacgtacg cggtgaccat ttcggcctgt cgccacactg tgccatcatc
    37741 gagcgccgcc tggccggcga gcgcacgcag caggctggac ttgcccgagc cgttgcgccc
    37801 gatgagcgcc acgcgctccc cggcgtcgag ctggaagctc acatgatcga gcaggtcgac
    37861 gtgcccgaag gcgaggcagg cgttatctac ggcgaggagc ggcatcttgg cgggcgcggc
    37921 gcgcgggccg cgggttcggt tcggggtggc gattttagcc ccgcgctggc ggctcgggcg
    37981 gaatcccgca taatgcagtg cacaaaaccg ctgcgcggcg acccggatcg gcgcgcgacg
    38041 gccgcagctt gcgcggccgc aaggcggata cggaacacag gaaacgaatg gaaaaactgc
    38101 tcgaacgctt cggccaggcc gaccaggacc cggtccgcct gtggtccgcg ctggtcgaca
    38161 agctgcgccc cgcgcgcccg accgaggccg acacggccgc cgggaacctg cgtgagctgg
    38221 gcaacctgct cgcacgccgg cccgacctcc tggcgaacct gcgcaaggcg gtcctcgagc
    38281 tcttcgccgg gcgcaagcag gtgacgatgt acgtctcctc cggcctgctg ccctcgaccg
    38341 gcttcttctc cgagacctcg cgccgcttcg gcagccgcat gctgcccgag ctgctcgaca
    38401 ccgcccacct caaggacctc ctctccgcag tcttccaccg cgtggatgac gaggagtggg
    38461 tgcgcgccat ccctgacgag gactggcagg acttcctgcg cctgctggtc ggtcaccaga
    38521 cgccgatgtt cgaggaggac gccagtccgc tgccgagcgc ggtgggcgag atcctcgagt
    38581 cgctgcgcgt gctctccttc cacgtctcgg cgatcgggct cgaccgcgag ctggtgcgca
    38641 tcgaccccca cctggaagag cacgaatccc ccttcctggc gcagaacgcc gagctgctcg
    38701 cctacatcgg ccactacaag gaatggtgga ccacccccgg cgcgctgatc gccgacgaca
    38761 agcacctgac cgtgatgctg caccagtgcg acgaggtgct gcagcgggtg cgcaagcgcg
    38821 cgatgcgggt gggcaccagc ctgacgctga ccttcaagct cgagcgcctg cgccagcacc
    38881 tcgagcgcat ccacgacctc atcgccctgc tcggcgagct gcgcacgcgg cgcgtggtcg
    38941 aggacgcggc gccgcgcatc gtgcgcctgt tcaagaccct ggtgcgcgcc gaatgccgca
    39001 agaacatcct ggccgactac tggggccaga acgtcgagct gctgtcgctg cgcatgaccg
    39061 agagcgcgag ccgcaccggc gagcactaca tcaccagctc gcgcagcgag tacttcggcc
    39121 tgttcgcctc ggctgcgctc ggcgggctga tcatcgcctt catggcggcg aacaagatcg
    39181 tgctcggcag ccagggcatg gcgcccctca acgagatgct ctccttctgc ctcaactacg
    39241 gcctcggctt cgtgctgatc cacatgctcg gcggcacggt ggcgaccaag cagccggcga
    39301 tgaccgcgaa cgcgatcgcc gcctcgatcg gcgaggccaa gggcaagacg cgcgacctgg
    39361 aggcgctcgc cgacctgatc gtgcgcacca tccgcagcca gatcggcgcc atcctgggca
    39421 acatcggggt ggcgatcccg gtggcggtcg gcgtgggcgt gctgatccac ctcgccaccg
    39481 gcagccactt catcagcccc gagaaggcgc acacgctgct cgacgagatc catccgctcg
    39541 gcggcgcggc gttcttcgcc gcgatcgcag gcgtctgcct gttcatgtcc gggctgatcg
    39601 ccgcttacta cgacaacctc tccgcctaca accgcatccc gcaacgcctc acccagctgc
    39661 gcggactgcg tcgcctgctc ggcgagcgcc ggctgcacgg gctggcggac tacgtcgagc
    39721 agaacatcgg ggcgctcgcc ggcaacttct tcttcggctt cctgctcggt ggcgccaccg
    39781 gcctgggggt gctgttcggc ctgccgatcg acatccgcca catcgccttc tcgtcggcct
    39841 acctcggcta cgcctcggcc gcgctggact tctcgatccc gctcacgacc gcggcgatcg
    39901 ccttcgccgg cgtgctgctg atcggcctca ccaacctggc ggtgagcttc gcgctgacgc
    39961 tgagcgtggc gatgcgcgcg cgccgcatca ccttcgcaca gagccgctcg ctcggcggcc
    40021 tgctgctgcg ccgcctgctg cgcacgccgc acgccttcct gttcccgccg cgggcggatg
    40081 aagcggcgct tggtccgacg ccgccgaacg gctagaatgc gcgtccccga gtcctcgtca
    40141 tagttcaatg gatagaacgg gcgcctccta agcgccagat ccaggttcga ttcctggtga
    40201 cgggaccact cattcgcgat ttcggtgttg taaacggttg ggggccactt gctcggcagg
    40261 cgcccgattc ggggaccgga cccgcttccc gaccggtcaa gcccgatgcc ccgctactgc
    40321 caggtgctct tcgatctcga cggcaccctc atcgactccg cccccgccat cctcgcaagc
    40381 taccgcgacg cctttgccag caccggacac cggccggtga tcgcgatcga cgcgggcatc
    40441 gtcggcccgc cgctgctcga gaccctgcgc atgctcgccg gcacccgcga cgccgcggtg
    40501 atcgacgcgc tcgcggccgg cttcaaggcg agctacgaca gcaccggcta ccgccagacc
    40561 gcggcctacg aaggagtcga cgcgatgctg cgccgccttg gcgcggccgg ctgcacgctg
    40621 tcgatcgcga ccaacaagcg cctgctgccg acgcggctga tcctcgaaca tctgggctgg
    40681 agcggccatt tcgcggcggt gtatgcactc gatctgttcg agccgcgcct gcccgacaag
    40741 gcggcgatga tcgcgcggct gctgcaggat cgcggcatcg accgcgccga tgcggtctac
    40801 gtgggcgatc gcggcgagga tggcgaatcg gccgatgcca accagttgcc cttcatcgcc
    40861 gcgacctggg gctatggcag cctggaggcg ggcgagatgg cgccgcactg gcgcgcggtg
    40921 gcaagcccgg cggcgctcgc cgacgagatc ctgggcgagg cctgatgtcg atcttctgcc
    40981 gttgatcctc tgccggggcg cgcctagcgc tgggatgcga tcaggcggtg gaggtattcg
    41041 accggaatcg catagctgat gcccgacggg tcggagagca ccttctcctt ggtcgacttc
    41101 acgaacacca tgttgagcac gccgatgacc tcgcccgtgg cggggtcgta gagcgggctg
    41161 ccgctgttgc cgggataggc ggtggcgtcg agctggtaca cccggaaggg gtcggtggcg
    41221 aggcgacgga tcagcgccgg gttgaggtcg cgcgagttgg cctgcgggat ggcgatcggc
    41281 gtgatcgccg agacgatgcc gcgatgcgtc accggggtca tgccgagtac ggcgccgatc
    41341 gggaagccgg tgaaggcgac ctcctgcccc tcgaccaccc cgccgccgcc cgcgaggcgt
    41401 agcgccggca gcgcaggacc gctctcgagg cgcagcaggg cgagatcctg cgcccgttcg
    41461 cttgccacga cccgcaccgg tcgtaccgcc ccggtgaggc cgtcgccggg cagcacgacc
    41521 acgagctgtt caagcttcgc gctgtcgacc tggtcgggca ggacgtgcgc gttggtggcg
    41581 atcgacatgc cgtcaccgac cgcaaagccg gtgccgcgga acacgaaggc cgggctgcgc
    41641 gtgcgctgat aggtcccgac tccgaccacc gacggcttga cgcgcgcgag cgtggagacc
    41701 aggtcggcgc gcgcgcaggg ggtgagggca agcgccagcg gaatcgccag cgcgcaggcc
    41761 agcaggcgac gccgcgccgg cattgtcgcg ccgggattca cgattcgtgt tcctgttcga
    41821 gggccagccg cagcttgcgc agcatcgggc tgggcgcgac cacccggctg tcgtagggat
    41881 ggcgatcctg gccgacgtgg cgcaggatgc gctcgacata ggcgcgcgtc tcgcggtagg
    41941 gcggtacgcc ccgatagcgg tccaccgcgc cctcgcccgc gttgtagccg gcggcggcga
    42001 gcgcgatgtc accttcgaag taggcgagca gccagcgcag gtaggccagg ccgccacgga
    42061 tgttctgctc ggggtcgtag ggcttgccga cgttgaagcg ctcggcggtg gcggggatca
    42121 gctgcatgac gcccatcgcg ttcttgggcg agagcgcctg cggattgagc gccgactcgg
    42181 tgagcccgat cgcgagcgcg aactcggggc ggacaccgta tttgggagcg agctcggcga
    42241 gcatgcgcgc caccgcctgg cgggccgcag gcaggcgcgc gatcagggcc tcgaccggcc
    42301 agcgctgcac gatctggctc gaaggggtgt gcaggcaatc cggcacctca ccggtgtatt
    42361 cgccggtgta gcgcaacatg cgctccgcgt gctcgtcgcc cttcgcggcc gccatggcga
    42421 agagcgtgcc ggcgtaggcg tcgttgcgct cgacaccgcg gccgttcgcg tacatccagc
    42481 cgagcgcata catgccttcg gcatcgccga ggcgagcgga ttcgcagtac agcagcgccg
    42541 cgtagggctg gtcgcgcggc acgccctcgc cgtgctcgta ggccagcgcc tcggtggcga
    42601 gatagcgcgc ctgctcggca agtgcgcgct cgaacgcccc ctccccggcc acggcaggaa
    42661 ccgaccacgc caaggcaagc gccacggcga ccgccccgcg cgcacgccca cgcgcccgcg
    42721 aggcgagcct cgcggtccga ccggcaagcg atgtcctgtt cttgcgcgtg ttcatgcttc
    42781 cttatcgcac agagcgggca gccctgacaa tcccgcctgg ctctcaatcc catgcagcga
    42841 cgctgccgct gccggcaggg cagcggcaag cgcaggcggg ttcatcggct gctcgtcttt
    42901 ctgccccggc ctcgccgggg gtcagagttc cttcatcagc gcggcggcct gctgatgcat
    42961 gggcgtgcca tccttgaggc gcggcatcag ggcctgcagt tgcgtgcgcg cctcgtcctt
    43021 cttcccggcc ttgaccagcg cccgtgcgag gttgagctgc aagggcagca ggtcggggcc
    43081 gatcgaaacg gcacgacgca agttcgccag accggcatcc actgcaccgc tttccacctg
    43141 gatggtgcct acggtatcga tgatcgccgg attttcgggc gcaagccgca gcgcctgctc
    43201 ggcgtactcc agcgccttcg gatccttcac ctcgttggcc gcccaagcca ggttgttgag
    43261 caggatcggg ttctgcgggg ccatctcgga catgcgcgcg aagatcttga ccgcgtcggc
    43321 gtagcgcttt tcgccaaggg ccagctcgcc caggtagccg cgcaacacga gatcggacgg
    43381 attgtccttc agccacgcgt cggccatgcg tgccgcgtcc gccttgcgat ccgcacggac
    43441 cagggccgaa tgcaggcgtg ccgcagcctg gcctccgccc ttgcgatcga gcgccttgcg
    43501 gtaggcagcc gcggcctccg accactggct ggcgaccgca tgcacgtcac cctcgagcag
    43561 gtagccggcg ggcagctcgg gctgccgcga ctgggcctcg ccggcgagtt gcagggcgag
    43621 cttcctgtcg ttgcgctcga gcgccagcgc gatcatgcgc tggcgtgcgt cgatgagatc
    43681 gggggcgatg ctcagcgcct tgcgcaaggc ctgctccgcg gcatggccgt ccttgagcga
    43741 acgatgcacg tcggcgaggg ccaccagcgg ctgcggcgac gccggcagca ggttgaccag
    43801 gcgattgagc gcggcgatcg cctgctgact gtcacccgcg gcaagttggg tgcgggcaag
    43861 cgcctcgatc gcgcgcggct cgctctggtg cgcagccgcg accttctggg ccacctgcag
    43921 cgcctgtgtg gcctgccgtt gcgagagcag gtgctggatg atggcaaggt tcgcccgcac
    43981 gctgccgggc gaagccgcct cggcgcgctc gagcgtgcgc agcacctcgg gcgctgccgc
    44041 ccccgtggcg cgctggatct cggcgagcgt cagcaaggcc tcgacgttct tggggtcgtt
    44101 cttgaccacg gcctcgagac gggcaatcgc atcctgcggc ttgcgttcgg cgaggtcgag
    44161 ccgcgccagg ttgatcgccg cggcgaggta gccgggctgc cgggcgagcg ccttctcgaa
    44221 ggccgctcgt gccgccggga tgtcgcgtcg ggcgagcatc agcccgccac gcaggttgtc
    44281 gaccagcaca ttgtccggtt gcttgcgctc gagttcggcc tgcgcggcga gcgccttgtc
    44341 gatctcgccc cggcgcaggt gacccaccac cagcgcgagg tccgcctgga tcccgctctc
    44401 gtccatgcgc gccgcggatt cgagatcctc gaaggcgctg tcgatgtcgc ctcccgccat
    44461 gcgcgccacg ccgagccgca tgcgtgccct cggatcatcg gggctcgcct tcgacgcaag
    44521 ttcgaaatac tcctccgagc gttcgaagtc gccgttggcg aggaagacct gccccgccag
    44581 cccgagcagg cgggcactcg gctgctgcgc ctgcaacagt ggctggagca gttcgagcgc
    44641 gcgcttggat tcgccggtgg cgaggtggga gacgatcagg gcctgccgag cgccgagatg
    44701 tccaggcacc gcctgcagca cccggtcgag atgggtgcgc gccaaagcat gctcattggt
    44761 gcgtacgagg acggtgcccg cgagcagatc cgcgggcagt agctgcggcg cgtccttgag
    44821 gacctgcatg acgtcgtcgc gagcctcggt caagcggttc tcgcggaaat gccggagcgc
    44881 gaccaggtag cgggtcaatg gatgattgcc cgccacggag cgcatgcttt ccagcgcagc
    44941 atcggccgcg gccatgtcgc cgccgcgcag caactggctg acgagggcga agtggccatt
    45001 caccgacttc ggctgcaggc gcacgacttc gcgcagggct tcgaccccct cgggggcacg
    45061 tccctggccg atcaacagat cggccagcag tgcgtgggcc tcggccgcct ccggcgagcg
    45121 ccggacggcc tcgcgaacct cggcctcggc ggccgcgaga tcgcccttga gggcggtggt
    45181 gcgggcgagc ccgatatggc tccgcgcctc gtcgggcgcg gcggcgatcg actcgagata
    45241 ggatgcgcgc gccttgtcga cgtcccgtcg cgccaggtga gcgtcgccca gtgccgccaa
    45301 gaccgccgca agcgccttgg gctcgctcac acgcgggtcg ccgaactcgg cgaagagctt
    45361 gtcgacctca cccgcggcga cgaatgccgg ggcgagctcg accgcgacca cgtcgcgcgg
    45421 atggccgagc tcgagcgcac gctgcaactc cttgactcca cccgccacat tgccctggcg
    45481 cagattgatc cgcccgagca ggaagcgcgc ctcggcgagg ttgccgttct gctgcagggc
    45541 gttcttgagc tggatgctgg cggcgtcaag gtcctgcttc tcgatgaagg ccttcgccga
    45601 caccaccatc tcttcgggcg tctcgctgca gccggcgagc agcaataccg acagggcagc
    45661 agcagcgaca ccggatgcgg cacggccgga ccagcgcgaa cgacgactac ggacttggct
    45721 cacgaaccat tctccttttt gaggccgaaa cggccgagca gatcatatag ggacgggcgg
    45781 ctgacgccga ggatctcggc agcgcgcgcg atgttgccgt tggtgcgggc aatgaccttg
    45841 aggacggcgg cgcgttcggc atcctcgcgc acctggcgga gattgaagat cgacaggtcc
    45901 tcgtccccgg cggcgaggcc gaggtcctct gcactgatgc agtcgccgtc ggccatgatc
    45961 acggcgcgct tgatgcagtt ctcgagctcg cgcacattcc cgggccagcg atgggcttcg
    46021 atcgccgaga gggcgtcgtc ggcgagcatc ggggcgcggc gaccgttttc cttggcgaag
    46081 cgctgcacga aggcgtgggc gaggaaggtc gcgtcgccct cgcgctcgcg caaggcgggg
    46141 atctcgatga cgatctcggc aagccggtag tagaggtcct cgcgaaacac gccggcctgg
    46201 atctgtgcct tgagatcacg atgcgtcgcg cacacgatgc gcacatcgac cgggatctcc
    46261 tcgcgcccgc cgatgcgctc gatcgagcgc tcctgcagga aacgcagcag cttggcctgc
    46321 agggcgagcg ggaggtcgcc gatctcgtcg aggaagagcg ttccgccgtt ggcggtctcg
    46381 atcttgccga gggtctggcg caccgcgccg gtgaaggcgc ctttctcgta gccgaagagt
    46441 tcgctctcga gcagggtgtc ggggatggcg gcgcagttga tcgcgacgaa gcgctcgcgc
    46501 gcgcgcggcg acaacatgtg cagtccgcgc gcgaggatct ccttgccggt accgctctcg
    46561 ccgagcaggg cgacggtggc cgacgcggag gcgagcttct cgatcgtgcg gcagatcttg
    46621 agcatgccgg ggtcgcgggt gagcagaccg gagagcgggc tgccttcgag cgcggcgagg
    46681 cgagcgttct ccatctgcag gtcgtgcatg cgaaatgcac gctcgatggt gaggttgagg
    46741 agctccggct cgaagggctt ggcgaagaag tcgtaggcgc ccaggccgac ggccttcacc
    46801 gcgttctcgc ggtcgtgctg tccggtgagc acgatgacct tggtgtcggg tgcgagcgtg
    46861 aggatctcgc gcaggagctt gaacccttcg ctcacgtcgt cgggcgcagg cggcagcccg
    46921 aggtccatcg tgaccaccgc gggttcgtgc ttgcgaagct gcgcgatggc gctctcgcga
    46981 tcgctcgcga ccacggtctc gcaggcgtcg aatgcccagc gcatctgctt ttgcagcgcg
    47041 agatcgtctt ccacgatcag gagggtgcgc tgcttgtctg acgtcgaatt cactgtctat
    47101 gtgcccatcg cggtagattg cccgtcctca cgccggatgc ggggtagctc gatggtgacg
    47161 cgcgtgccgc gcccgacctc gctatcgtag tgcagcgcac caccgatttc ctcgaggtac
    47221 tgcctggtct cgtagacccc gatccccatc ccgctcgact tggtggtctg gaagggtcgc
    47281 gagagccgtt cgcggacgaa ctctgcagtc atcccgcaac cattgtcctc gacgaccacg
    47341 ttcgcccgcc cgtccgtccc ggctgcgaga gtcaaggtga ccttaccatc ctgtggcgtc
    47401 gcatccagtg cattttgcac gacatgaccg acgattcttt ccagcctctg cgggtgggcg
    47461 ctgacctcga ccgacccggc gccctcgagt gcgatctcga cgaccggcag ctgcccgcgc
    47521 ttcgagtcgc agaccgcacg cagcagtgcg ggcagatcca gcgcccgcgg cggatcgatc
    47581 gagcgcttct cctgaagctg ggtcatcagc ccgcgcatgc gcgcctccac gttcgccacc
    47641 gtctcgagca tgtcctgctg gaactcaggg ttgtcacgat ggcgctgcgc gttcttgagc
    47701 atcaacgaga gctgggcgac gagattcttg aggtcatgaa ccacgaaggc ggacatgcgg
    47761 ttgaaggagt cgaacttgcg cgcctcgagc agggcctcgg ccgcaagcat gcggtcgaga
    47821 tagcctgcag cctggcgttg cgccgtcttg agcaggtcga gcacctccca gtcgatatcg
    47881 aagggcgcgc gtggagaact gagcacgacg aacccgataa ggcgctcggc cgtctgcagc
    47941 ggaatgacca gccaggcgtc gtcgagatgc gagagccacg ccggcagcac gagcccctcg
    48001 tagcgtccgg gctgcatgcg gtactcctcg aggtcgacca cccagcctcg gccggccaga
    48061 aaggcgcaca gcggcgagtc gaggctgtcg acggcatcga ccacggggtg gttgaagcgc
    48121 gaatgcagct tgcacttgcc gtagccatcg gcaagccaca gcgctccccc gggactctcc
    48181 accagatcgg acagggcctt gatgaccgac tgcccgagat cgaggctgcg gtcggcagaa
    48241 gacagcgcct gggtgaaacg cagccattcg gcgcggtagt cgtagcggta gggaaagaga
    48301 tgcttgctga tgaagacgcg caggcgggcg cgcaccgccc ccgagaacag cagcgccccg
    48361 agcagcacga gccccgcgaa gaggagcgcc atctgcagcg cgcgtcccca gtcgccaccg
    48421 aagtagcgca cgtaataagc ggcgccggcg atgaccagga gatagagccc cgccccggcc
    48481 agcgcggtcg aatggaacac cacctcgcgc gagaccgaca tgcgcagggt ccacgacggg
    48541 ctgcgcgttc cggcaatcgc gatcagcggg atcagcagtg catgggcgat accccgtgtc
    48601 gccaagacgt cggcgtcgag gcgcgagaac agcaaggcat cggcgaacag gtagagttcg
    48661 aagatgtatc ccgccgcaag tgcgaggcag agcggcttga gcccccaacg cgagacggag
    48721 ggcatgcccc ggtagagttg ctcgacgagc atcagcccca cgaccgcatg cgttagccac
    48781 gcaccgataa cgggttctac cggcagcgta cccgcgagcc ccgcccactc gagcatcagc
    48841 gcaagaatct gcagcgacac ggccgccacg gccgcatacg ctggccagcg caaccatcca
    48901 ccccacagag gtcgcgagag cacgatcagg aacgcgtacc aggcagccac gcgcacaacg
    48961 tcgaggatga ccgcgacggt gccgatcagc gccccgtctc cacgcgcggc gagcgcggaa
    49021 catgctgccc acagaccaga aatggcgacg gcggcgaaca acacgccacc cggaagcgcc
    49081 cccctccagg cgaagaaaat gtatagcgcg aagaaggcaa aggctacggc tgcaacccca
    49141 tagctccaga tcgcaacctc agccaccccg cccccctcgc cgtctcatcc gcagcacatg
    49201 cccgcccgaa tcacctgcgg cttcggcccg cgcgcgcggg ctcagtgcgc gccttcgccc
    49261 gtcagcacta cccggacggt ttcgaagagc accagcgtat ccagaatcaa ggagtgattc
    49321 ttcacgtaat agaggtcgta ctggagcttc tcggcagcat catcgaccga ggctccgtac
    49381 tggtaccgca cctgcgccca acccgtgaca ccgggcttga cgcagtggcg cacggcgtag
    49441 aacgggatct gctgggtcag ctgatcgacg aaatacgggc gctccgggcg cgggccgacc
    49501 aggctcatgt cgccattgag gacgttgaag agttgcggaa gctcgtcgat cctgagcttg
    49561 cggatgaagc gtccgatccg tgtcacgcga tcgtcgttcg aactcgccca tctgggcttg
    49621 ccgtccttct ccgcgtcccg gcgcatgctg cggaacttga tcacccggaa gggtcgaccg
    49681 ccccgcccca cccgctcctg cgagtagaag atcggcgcgc cgtcctccag gacgatcaac
    49741 agggccgtca acaccatcac cggcatcgct acgagcagga gcacagtgcc gaccacgagg
    49801 tcgaagcagc gcttgacgaa ggtacgcgtc cagccttggc gaaagccgtc cccgtagatc
    49861 agccagctgg cccgcagcga atccagccgc acctggccct ggacgcgctc gaagaagctc
    49921 gacagatcga ggatgcgcgt gccaaggagc ttgcaatcga gcagctcgcg caaggaaagc
    49981 actccccccc tgcgctcgcg gaccgcgacg atcacctcgt ccacgcgaag gttgcgcacg
    50041 acgtcgagca gactgcccgg cggaagcacc tcgcgcggct cgacctcgat gcgttcattg
    50101 cccccgaccg gcaggaaacc gaccacgtcg acactgcgct gcaacggccg tgtcaggtcc
    50161 tgatgcacca tcctcgcgtc cctccccgtc ccgacgatca gcaccctcgg cacgaacagg
    50221 gccgacgcct gacgctgatt gaccaggccg cgcgcaagaa ggaggaagca taggagcagc
    50281 agtacactga cctggagcga atggggctca atctcggacc acggcaacag cccgaaaacg
    50341 agataggcta ccggcacact gaccgtgagc gagagcgcca cgcgtgcgaa ggcctgccgg
    50401 tgcgagcgtt ggtacaccgg ccggtacaag cccatcgccg cgttgagtgc gatcatgctc
    50461 gcagcgaacg tgagcgccga cggaatacag accgcccaat cgaccgcact tgtgggtgta
    50521 acgagcaacg caactgcccc gagcacgacc gcaaatagcg tcaatgcgtc gaacaacacc
    50581 tgctgcaggg tgtgcgtggg aaggtaatgg ctgaacacct tcaacatcga gggcctctgc
    50641 attggtttga gaagagatgg agcggtccca agctggagga ccctggcgga gtgcgacgcg
    50701 ctcgcccccc cccccgctca cgatttgagc ttagacaatc gctgaccgga cacgcgtgac
    50761 gcacatcacg tcgaaggccg ctcaggcccc catttcgaac ccgacgagca caatcacacg
    50821 cgcgccatcg gaagaggaaa tgccgcactg caacattcgc ggttgatttt agcatgcgaa
    50881 ggttgtagcg tcggctacgt taccccagaa cgctttcata caaggagaag caagtgaccc
    50941 aacctcaacg cgatttcagc gaggtctacg gcctcggttt cgaagacctg cacgttggcc
    51001 ggaccgcctc ggtctcgcgc accgtcagcg aggccgacat cctcatgttc gctggtgttt
    51061 cgggcgatac caacccggtc catctcgatg aagagtttgc cgcgagcacg atgttcggcg
    51121 gccggatcgc gcatggcatg ctatctgccg ggctcatctc ggcggtattc ggcacccgcc
    51181 tgccaggccc cggctgcatc tatctgtcgc agagcctgaa attcaaggcc ccggtgaaga
    51241 tcggcgacac ggtcgtggcg cgcgtcaccg tcaaggagct gaaggccgag aagcgtcgcg
    51301 ccgttttctc gacggtctgc accgtgggcg acaaggtggt catggacggc gaagccgaga
    51361 ttctcgttcc ggcccgcggc tgatccacgg tgctcgcgac ctgcgtcgcc ccggcgaggc
    51421 gatgcgatgc agcgcatcgc cagccactta cgacagcggc gcaggtcggg atgaaacact
    51481 ggatggcagc gcaggccagc aacgaaggcc tcggctgcgg tggcggagcc gaacggttgc
    51541 acagtccggt ttcgacctgc aggcggacct gctttcggga agatctctga ggcgacgcgt
    51601 tggatctcgt gacgggtata cggcgcaacg ccccaggcac gaagaggtgc gtggggcgtt
    51661 gttttgtggg
//
LOCUS       DAOTIN010000013        50323 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_706_length_50323_cov_8.853147, whole genome shotgun sequence.
ACCESSION   DAOTIN010000013 DAOTIN010000000
VERSION     DAOTIN010000013.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 50323)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 50323)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50323
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_706_length_50323_cov_8.853147"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(168..1721)
                     /locus_tag="P5537_03555"
     CDS             complement(168..1721)
                     /locus_tag="P5537_03555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoVR family protein"
                     /protein_id="HRV77150.1"
                     /translation="MKTTRPRTRGRAAKSPLPSGSEWTVEAIDRYNDEIARVAAHYKL
                     DIYPVQVEIITAEQMMDAYASVGMPVNYHHWSFGKHFLATEKGYRRGQMGLAYEIVIN
                     SNPCIAYLMEENTLTMQGLVIAHAAYGHNSFFKGNYLFRTWTNADAIIDYLLFARNYI
                     TQCEERHGEEAVELLLDSCHALMNLGVDRYKRPPRLSLAKEKLRQQEREEYLQSQVND
                     LWRTLPAHDVRADARAEARFPPEPEENLLYFVEKNAPLLEPWQREVVRIVRKIAQYFF
                     PQRQTQVMNEGWATFWHYTLLNHLYDEGLLADSFMLEFLQSHTNVVAQPPYNSRWFSG
                     INPYALGFAMWRDLRRICEDPDEEDRRWFPEIAGSDWLETFDFAMRNFKDESFIAQYL
                     SPKVMRDFRLFAVLDDDHEDKLQVSAIHDDAGFRKLREILSDQYNLGAREPNVQVWNV
                     DLRGDRSLTLRHTAFRRRPLGDGTDEVMRHLARLWGFTVRLERAGDDGKIELLHEIRA
                     ETTRPRAPA"
     gene            complement(1718..2986)
                     /locus_tag="P5537_03560"
     CDS             complement(1718..2986)
                     /locus_tag="P5537_03560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeaH/YhbH family protein"
                     /protein_id="HRV77151.1"
                     /translation="MVRIIDRRFDSKNKSAVNRQRFMRRFKQQIRKAVSEAIHGRSIR
                     DLENGEQISIPARDLSEPSLHHGKGGVWEQVFPGNDQFSTGDRIKRPLGGGGDGAGKG
                     KASQDGEHEDDFVFQLSREEFLDLFFEDLELPRLIRTQLAKVTDYKTRRAGFTSDGVP
                     ANINIVRSMRGALGRRLALGSPWAARIRELQQELDEALARGGEDSEEVRGLREELAAL
                     RARIDRIPFIDRFDLRYNNRIKEPRPTTQAVMFCVMDVSGSMDEERKSMAKRFFMLLY
                     LFLTRSYEHIEVVFIRHHTVAKEVDEDEFFHSRESGGTVVSSALELMRGILRERYANG
                     QWNVYGAQASDGDNWDNDSPVCGRLLGKEILPWCQYFAYVEITAGEPQNLWREYAKLE
                     AAHDNFAMQRIESPADIYPVFRELFKKTLA"
     gene            complement(3063..4985)
                     /locus_tag="P5537_03565"
     CDS             complement(3063..4985)
                     /locus_tag="P5537_03565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018992475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PrkA family serine protein kinase"
                     /protein_id="HRV77152.1"
                     /translation="MSIFNAYQARFEAAREEEMSLQDYLELCRTDRMAYATAAERMLA
                     AIGEPELVDTRLDPRLSRIFSNKILKLYPAFRDFYGMEEVIENIVSYFRHAAQGLEEK
                     KQILYLLGPVGGGKSSLAEKLKSLIERVPFYAIKGSPVNESPLGLFNAAEDAHILEGD
                     FGIPRRYLGGIMSPWAVKRLHEYGGDITRFRVVKLSPSVLRQTAVAKTEPGDENNQDI
                     SSLVGKIDIRKLEQYSQDDPDAYSYSGGLCLANRGLLEFVEMFKAPIKVLHPLLTATQ
                     EGNYKGTEGFGAIPFDGIVMAHSNESEWVAFKNNRNNEAFLDRIYTVKVPYCLRVSDE
                     VRIYEKLLAHSSLSEAPCAPDTLKMMAQFAVLSRLKEPENSSIFSKMRVYDGENLKDT
                     DPKAKSYQEYRDYAGVDEGMTGLSTRFAFKALSKIFNFDHREVAANPVHLMYVLEQQI
                     EAEQFPAETEARYLGYIKEYLAPRYAEFIGKEIQTAYLESYSEYGQNIFDRYVIYADF
                     WIQDQEFRDPNTGEILDRAALNEELEKIEKPAGISNPKDFRNEVVNFVLRARAKHEGR
                     NPSWTSYEKLRAVIEKKMFSNTEDLLPVISFNAKASADEQKKHQDFVDRMIDKGYTEK
                     QVRLLCEWYLRVRKAS"
     gene            4978..5109
                     /locus_tag="P5537_03570"
     CDS             4978..5109
                     /locus_tag="P5537_03570"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77153.1"
                     /translation="MDMVVSSSGAMRRERGCRKVKQDRVFRLLGGARLAFTGCRVCT"
     gene            5357..6661
                     /gene="tig"
                     /locus_tag="P5537_03575"
     CDS             5357..6661
                     /gene="tig"
                     /locus_tag="P5537_03575"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HRV77154.1"
                     /translation="MEQNQVTPSALERRIDISVSLADIEKEVDARLKRMARTVKMPGF
                     RPGKVPMKIVAQTHGGQARGEAVGAAVEKAFGEKVRADNLRVAGYPSIEPKDGAAEGT
                     LEFTAVFEVYPDVVVGEFAGRKIERPVLNVGDAEVDKTIEVLRKQRTGFKAVERAAAA
                     GDRVVIDFTGRMDGEVFDGGQAQDFPFVVGAGSMLKDFEDAVVGLAAGEGKTFDMTFP
                     EDYHAANLAGKQVQFEITVKAVEEPVLPEVDADFARSLGVADGDVAKLREEVKGNLER
                     EVKRRIQSRLKEQVMDALIEVAPIDVPKALVQAESNQLADNARRDLEMRGLKTKDIPV
                     DPSWFKDQAERRVKLGLIMAELVKASELHAKPEQIRALVEEMAQSYEDPSELVRWYYA
                     QPERLAQAEAVVIEDNVVEWVCAKADTSDKEVAFDELMGNAA"
     gene            6682..7320
                     /gene="clpP"
                     /locus_tag="P5537_03580"
     CDS             6682..7320
                     /gene="clpP"
                     /locus_tag="P5537_03580"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HRV77155.1"
                     /translation="MMQGTPQHSSDWNPVGLGLVPMVVEQSGRGERAYDIYSRLLKER
                     VVFLVGPVNDVTANLIVAQLLFLESENPDKDIYFYINSPGGSVTAGMAIYDTMQFIKP
                     NVSTLCIGQAASMGAFLLAAGEKGKRFILPNSRVMIHQPLGGFQGQASDIEIHAREIL
                     YLRSRLNDMLSKHTGQPLERIEKDTDRDNFMSATAAVEYGLVDKVLTSRDDT"
     gene            7339..8607
                     /gene="clpX"
                     /locus_tag="P5537_03585"
     CDS             7339..8607
                     /gene="clpX"
                     /locus_tag="P5537_03585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011765801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HRV77156.1"
                     /translation="MTDKKAGGEKLLYCSFCGKSQHEVRKLIAGPSVFICDECIELCN
                     DIIRDEVVGAEGGEGIKGTLPTPHEICSILDQYVIGQSLAKRSLAVAVYNHYKRLRHI
                     DARQDDVELAKSNILLIGPTGSGKTLLAQTLARLLDVPFVMADATTLTEAGYVGEDVE
                     NIVQKLLQKCDYDVDKAQQGIIYIDEIDKISRKADNPSITRDVSGEGVQQALLKLVEG
                     TVASIPPQGGRKHPNQDFIQVDTTNVLFICGGAFDGLEKVIRNRTEKVGIGFGAEVKS
                     KEGKNLTDTFRQVEPEDLIKFGLIPELIGRLPVVATLQELDEAALIQILIEPKNALVK
                     QYQKLFSMEGVELEIRPNALHAVARKAIKRKTGARGLRSILEVALLDIMYDLPTLDDV
                     AKVVVDESTIEDGGKPLLIYAEQQKVSGAN"
     gene            8727..11150
                     /gene="lon"
                     /locus_tag="P5537_03590"
     CDS             8727..11150
                     /gene="lon"
                     /locus_tag="P5537_03590"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HRV77157.1"
                     /translation="MSGHAALPNEAMELPLLPLRDVVVFPHMVIPLFVGRPKSIKALE
                     SAMEDGKSILLVAQKSAAKDEPAVEDLYDIGCIANILQMLKLPDGTIKVLVEGVQRAR
                     IERVEDMRSLFVASVRPVPVAEAPSHELEAMRRAIIAQFDQYVKLNKKIPPEILGSLA
                     GIEEAGRLADTIAAHLPLKLEQKQEVLEMFDTGARLDKLLGQLEGELDILQVEKRIRG
                     RVKRQMEKSQREYYLNEQVKAIQKELGEGEEGADLEEMDKKIKSAGMPKEALAKAEAE
                     FKKLRLMSPMSAEATVVRNYIDTLIGLPWKKKSRVSKDLGEAEKVLDKDHYGLERVKE
                     RILEYLAVQQRVDKVKAPILCLVGPPGVGKTSLGQSIAKATNRKFIRMALGGVRDEAE
                     IRGHRRTYIGSMPGKILQNMSKVGVKNPLFLLDEVDKLGMDFRGDPSSALLEVLDPEQ
                     NHTFQDHYVEVDFDLSDVMFVATANTLNIPPALLDRMEVIRLSGYTEDEKINIAQRYL
                     LPKQMKNNGLKREELSVTEEAVRDVVRYYTREAGVRSLEREISKVCRKVVKQLVLKSR
                     TSKVVVNAKNLDKFLGVRKYSFGMAEKENQVGQVTGLAWTEVGGELLTIEAVQLPGKG
                     KVVTTGKLGEVMQESIQAALSVVRRRARSLGIDPDFYQKSDLHIHLPEGAIPKDGPSA
                     GIAISTALVSVLTGIPVRCDVAMTGEITLRGEVLAIGGLKEKLLAAVRGGIRTALIPE
                     ENVKDLAEIPDNIKNAIEIVPVKWIDRVLELALERKPEPLPEEPAPAAPATPAAEGAE
                     GDKANLRPH"
     gene            complement(11244..12266)
                     /locus_tag="P5537_03595"
     CDS             complement(11244..12266)
                     /locus_tag="P5537_03595"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HRV77158.1"
                     /translation="MPSSVPLSVLDLAPITAGSTPADALRNTRELAQLADRCGYTRYW
                     LAEHHNMTGIASAATAVVIGHIAGATRRIRVGAGGIMLPNHAPLVIAEQFGTLESLFP
                     GRIDLGLGRAPGTDQTTARALRRNLVGSDDHFPQDVLELQSYFQPAGPGQAVRAVPGE
                     GLQVPLWLLGSSFYGAELAARLGLPFAFASHFAPRFLFEAVDLYRSNFRPSAQLDKPW
                     FAVAANAIAADTDAEAEYLLRSLQLRFAAMARGVRGQLQPPEAFVDTDWSTSELAFAE
                     QSLACSAVGAPDTVRQQLETLIERTGANELILTAQIFDHGARLRSLELVARAWGLPVE
                     DTVAGA"
     gene            12570..13361
                     /locus_tag="P5537_03600"
     CDS             12570..13361
                     /locus_tag="P5537_03600"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HRV77159.1"
                     /translation="MKKYALLCAVLALHAGASFAKDWNEIRMASEGAYPPFNTTTADG
                     SMAGFDIDIGNALCEEMKAKCTWVKQEWDGMIPALVSRKFDAIIASMSITEERKAKVD
                     FTDKYYASPLALIAKKGSELRPDLELLKGKKVGVQRGTVSDNFATKYWDGKGLQIVRY
                     AKQDEAYLDLRAGRLDAAFVDYLEAYGGFLTKPEGEGYDVAGDRLFGRNAEEKAVIGE
                     GIGIAVRKRDKELTEKLNQALAAIRANGKYDAIQKKYFPMDIYGN"
     gene            13467..14159
                     /locus_tag="P5537_03605"
     CDS             13467..14159
                     /locus_tag="P5537_03605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV77160.1"
                     /translation="MDALIEYSPSLLAGAWVTLKVALVSVLLALVTGLIGAACKLSGF
                     LPLRLWTMLYTTVMRGVPDLVMMLLVFYGGQVLLNLVIDHFGWDFIEIDPFVAGVLTI
                     GLIFGAYFTETFRGAFLAVSAGQLEAGRAYGMSTWQVFRRILFPQMLRFALPGIGNNW
                     LVLLKSTAIVSMIGLSDMTRIADQAGRSTHQPFTFYLAVCVLYLAMTALSSYGLGVLM
                     RRYSAGVRETQV"
     gene            14171..14905
                     /locus_tag="P5537_03610"
     CDS             14171..14905
                     /locus_tag="P5537_03610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV77161.1"
                     /translation="MELFDLSVITGSLPQFWRGLWMTLQLTGFALLFGFFAAIPLAVL
                     RLSPNRLVAAPVAAYTYFFRGTPMLVQLLLVYYGASQWEWMRAAWEAGHPVWTLFREP
                     YFCALFAFGLNTCAYTVEILAGSMRNTPHGELEAAKAMGMTRLKALQRIVIPSALRRM
                     IPAYSNEVILMLQGSAIASAVTLVDLTGAARDVYSRHFAPFEAFVFVGLIYLALTFVL
                     VGLFKLAEHRWLAHLAPRKAEAGRQS"
     gene            15018..15800
                     /locus_tag="P5537_03615"
     CDS             15018..15800
                     /locus_tag="P5537_03615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HRV77162.1"
                     /translation="MNHKASVEQVRVEDLHKSYGDHEVLKGVSLTANSGDVISIIGSS
                     GSGKSTWLRCINFLECPTAGRILVAGKEVELVRNRKGELTVKDARQLQQIRTRLSMVF
                     QHFNLWSHMTVLENVVEAPVHVLGLSKAEARERAERYLERVGVWKLRDAYPAHMSGGQ
                     QQRVAIARALAMEPAVLLFDEPTSALDPELVGEVLKVMRSLAEEGRTMMVVTHEMGFA
                     REVSNHVIFVHQGRVEEEGDPKVVLVRPRSERLQQFLSGNLK"
     gene            complement(15826..16758)
                     /gene="rocF"
                     /locus_tag="P5537_03620"
     CDS             complement(15826..16758)
                     /gene="rocF"
                     /locus_tag="P5537_03620"
                     /EC_number="3.5.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004053 - arginase activity [Evidence
                     IEA];
                     GO_process: GO:0019547 - arginine catabolic process to
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginase"
                     /protein_id="HRV77163.1"
                     /translation="MENLKVSLIGVPTDVGAGVRGASMGPEALRVAGLGRAIAAFGAE
                     VRDCGNLAGPSNPELPAVDGFRHLDEVAAWNGAVHEAVYAELAEGRVPIMLGGDHCLA
                     IGSISAVARRCRETGRKLRVLWFDAHADLNTATMTPSGNIHGMPVACLCGHGPELLTG
                     IGGHIPAVAPAQIRQIGIRSVDEGEKRFLHELRVEVFDMRYIDEIGMRATMEQALAGV
                     DANTHLHVSLDVDFLDPTIAPGVGTTVRGGPTYREAELCMEMIADTGQLASLDIVELN
                     PALDHCNMTAELAVDLVESLFGKSTLMRMHRNYR"
     gene            17015..17923
                     /locus_tag="P5537_03625"
     CDS             17015..17923
                     /locus_tag="P5537_03625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HRV77164.1"
                     /translation="MRRAQANGLLLVAALIWGTAFVAQQTGMRDVGPFTFTGSRFLFG
                     AVMIAPLAFMELRRLGRRGTFLDVRDLLACALLGAVLFLGAALQQIGIMSTTVSNAGF
                     LTALYVPLVPIAGALLLRERSHWSVWPASLGCLGGTYLLGGGSLSALTVGDLWVIASA
                     LFWAAHVMLVGRVAARKGASVTVAMLQFLVVGVLGMAVGLGTEEVSTVALERALPSIA
                     YAGILSVGVGFTLQVVAQRHTPAADAAILLSCETLFAALAGRLVLGETLTVAQMSGGL
                     LIFACVLAVQILPLWRARRAVAVEAG"
     gene            complement(17934..19085)
                     /locus_tag="P5537_03630"
     CDS             complement(17934..19085)
                     /locus_tag="P5537_03630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019921695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HRV77165.1"
                     /translation="MFVGGFATFAMVYSTQPLLPLLAAEFDVGAASASLTVSATTAGL
                     ALMLIPGSVLADRLGRQQVMKAALAIAALLALATAFAPDFGALLVLRALLGGVIAGLP
                     AAAMAYIGEEIAPGAQARAMGLYIAGNALGGMSGRFVAALLTDWSSWRVALGVIGVLG
                     VISALVFWQRLPASRNFRARAATPARIFADTLAIYRDPGLPALFLVAFLAMGGFVGLY
                     NFLGFRLLEAPYGLGQSAIGAIFLLYLVGTWASAASGRLAERRGRRKVLWPMVAVMGA
                     GLLLTLAQPLWLVIAGVGVFTFGFFAAHALASGWVGRRAGERRALASALYLSSYYLGA
                     SVLGSLAGTAWTDWRWEGVAALVGLCVLLTGACALWLRRLPAPAGGAAD"
     gene            19280..20188
                     /locus_tag="P5537_03635"
     CDS             19280..20188
                     /locus_tag="P5537_03635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HRV77166.1"
                     /translation="MELRHLRYFVAVAEELNFTRAAARLRIGQPPLSMQIRDLEEEVG
                     ARLFERGPRRVALSAAGERFLPHARRILDGVEEAVAEARRAARGELGELRVGFTSSLP
                     FTDLLPDALNAYRRRFPAVRLQLRELFTPEQFAALARGELDVGFVRLQAGAPPAGIVL
                     REVARNPLRLVVNAAHRLADAERVSIAELAGEDFVGFPADVGTDLPGVLRNLCRQAGF
                     EPRVVQTAREATTQIGLVAAGLGVALLPAPLESVRIARVRYLALAEPEAQFRLALAVR
                     EGEPSPLLAGFLEVLERLRAGQASVT"
     gene            complement(20222..21220)
                     /locus_tag="P5537_03640"
     CDS             complement(20222..21220)
                     /locus_tag="P5537_03640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase/citrate lyase family protein"
                     /protein_id="HRV77167.1"
                     /translation="MSLHPAQVLFAGEKPFPSLPAVDHYAGAEKLMMKALKLQQELGP
                     VFDLTCDCEDGAQAGAEAEHARMVVEVVNGAENHFGRVGARIHDITHPHWQRDLEILV
                     GGAGRRLAFVTIPKVRSAADAAEQIRELRRVEAACGLERALPIHVLVETHGALREAWE
                     IAALDGVESIDFGLMDFVSGHHGAIPGSAMKSPGQFEHPLVVRAKADIAAAALANGVI
                     PSHNVTTELQDVAVIRHDAERARREFGYLRMWSIHPNQILPIIAAMQPDFSEVEEAAA
                     ILCAAQDNAWGPIRHQGRLHDRASYRYYWELLQRARNTGMELPGETRQRFFAGAGH"
     gene            complement(21362..22351)
                     /locus_tag="P5537_03645"
     CDS             complement(21362..22351)
                     /locus_tag="P5537_03645"
                     /EC_number="1.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015435434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016615 - malate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006108 - malate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase"
                     /protein_id="HRV77168.1"
                     /translation="MSKAPMRVAVTGAAGQIGYSLLFRIASGEMLGKDQPVILQLLDL
                     PQAQKAVKGVMMELEDCAFPLLAGMIATDDPNVAFKDADVCLLVGARPRGPGMERADL
                     LTANGAIFTVQGKAIAENAKEDVRVLVVGNPCNTNAYIARAAAIKVGRTNPNNYHGML
                     RLDHNRALSQLAAKSGREVSSLKKMVVWGNHSPSMYADYRFCESNGDSVKALINDHAW
                     NNDVFLPTVGKRGAAIIEARGLSSAASAANAAIDHVHDWVLGSSDWVTMGVPSDGSYG
                     IPEGVVFGFPCECKDGQFKIIQGLEIDEYSKGKIAITLKELEDERAAVADMLK"
     gene            22609..23337
                     /locus_tag="P5537_03650"
     CDS             22609..23337
                     /locus_tag="P5537_03650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015435435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HRV77169.1"
                     /translation="MSQESPTFSPLYRQIKALILQALEAGEWRPGQAIPSEQELAARF
                     SVSQGTVRKAIDEMAADNLLVRKQGKGTFVASHNDPRALFRFLRLVPVDGDLSPPQSI
                     PLDCWRAKAGQEASRMLAIEPGAPIIIVRRLLKFAARPVVIDEIYLPGEVFQGLSAET
                     LQGWNGSLYSLFETRFGVRMIRAQERIRAVAADRGAAEALNVQEGTPLLSVERVTYTY
                     GDKPVEWRRGLYSTAEHFYLNELN"
     gene            23438..23827
                     /gene="sdhC"
                     /locus_tag="P5537_03655"
     CDS             23438..23827
                     /gene="sdhC"
                     /locus_tag="P5537_03655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011765282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045282 - plasma membrane succinate
                     dehydrogenase complex [Evidence IEA];
                     GO_function: GO:0000104 - succinate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase, cytochrome b556
                     subunit"
                     /protein_id="HRV77170.1"
                     /translation="MSEVTARKPRPKYLALNEIRLPLPGIVSILHRVSGVGLFLMLPF
                     LLYLLDRSLGSPETFETFAAVVDNWFIKLILFGLLWAYLHHFCAGIRFLLLDLHKGLE
                     LEEARKSSKIVLVVSLTLTVIIGVVLW"
     gene            23821..24171
                     /gene="sdhD"
                     /locus_tag="P5537_03660"
     CDS             23821..24171
                     /gene="sdhD"
                     /locus_tag="P5537_03660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045282 - plasma membrane succinate
                     dehydrogenase complex [Evidence IEA];
                     GO_function: GO:0000104 - succinate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase, hydrophobic membrane
                     anchor protein"
                     /protein_id="HRV77171.1"
                     /translation="MVKQRIVVGAHYGLKDWIAQRATAVYMAAYTIIFALSAFSLREL
                     NYQEWSGLFSHGLFKFLSFLFFLSVFYHAWIGIRDLWMDYIKPNGVRLALHLVTIFVL
                     VGYAGWAAQILWRL"
     gene            24174..25967
                     /gene="sdhA"
                     /locus_tag="P5537_03665"
     CDS             24174..25967
                     /gene="sdhA"
                     /locus_tag="P5537_03665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011765284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase flavoprotein subunit"
                     /protein_id="HRV77172.1"
                     /translation="MNVAKRTFDAVIVGAGGAGLRAALQLSEAGLKTAVLTKVFPTRS
                     HTVAAQGGVAASLGNSTEDNWHWHMYDTVKGSDWLGDQDAIEFMCKKANEVVIELEHY
                     GMPFDRTDNGKIYQRPFGGHSMNYGQAPVMRSCAAADRTGHAMLHALYQRNVRANTQF
                     FVEWMALDLIRDADGDVLGVTAMEMETGEVSIFHAKATIFATGGAGRIYYSSTNAFIN
                     TGDGVGMAARAGIPLEDMEFWQFHPTGVAGAGVLITEGVRGEGGILRNAQGERFMERY
                     APNLKDLASRDVVSRAMTTEINEGRGCGPDKDHVLLDITHLAPDTIMKRLPGIREIAI
                     QFAGVDPIKAPIPVVPTCHYQMGGIPTNYKGQVVVPKDGNPNSPVAGFYAAGECACAS
                     VHGANRLGTNSLLDLLVFGKSAGETVVEDFQSGQLKLKPLPADAADVSLARLARLDGQ
                     TNGESVFDVGLEMRRTMQKHAGVFRFDNLLKEGVQKIGEVAERAKRTEIKDKSKVWNV
                     ARMEALELDNLIEVARATMVSAEARKESRGAHVRDDAPDTAENPNGRDDANWLKHTLW
                     YSEGDRLDYKPVNLKPLSDDVEPIALAKRTY"
     gene            25987..26697
                     /locus_tag="P5537_03670"
     CDS             25987..26697
                     /locus_tag="P5537_03670"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011765285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008177 - succinate dehydrogenase
                     (ubiquinone) activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase iron-sulfur subunit"
                     /protein_id="HRV77173.1"
                     /translation="MTKRTVQFKIYRYDPDKDEKPYMQDISVELEPSDKKLLDALVRL
                     RAKDDSMSFRRSCREGVCGSDAMNINGKNGLACLTDVDSLQQPITLRPLPGLPVIRDL
                     IVDMTQFFKQYHSIKPYLVNNDPPPERERLQSPEDREELNGLYECILCACCSTSCPSF
                     WWNPDKFVGPAGLLAAYRFLADTRDQDTGARLDNLEDPYRLFRCHTIMNCVDVCPKGL
                     NPTRAIGKIKDMMVRRAI"
     gene            26713..26949
                     /locus_tag="P5537_03675"
     CDS             26713..26949
                     /locus_tag="P5537_03675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase assembly factor 2"
                     /protein_id="HRV77174.1"
                     /translation="MTINRGRVRWQCRRALLELDLVFTRFLERHFDRLTDDQLADLDD
                     LLRCDDYDIWAWVNGSKACENDRWKEMIGLLRQG"
     gene            27014..28309
                     /gene="gltA"
                     /locus_tag="P5537_03680"
     CDS             27014..28309
                     /gene="gltA"
                     /locus_tag="P5537_03680"
                     /EC_number="2.3.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004108 - citrate (Si)-synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="citrate synthase"
                     /protein_id="HRV77175.1"
                     /translation="MSTERTATLTVDGKTVEFPVMTGTHGQDVIDIRTLGGKTGLFTY
                     DSGFLSTASCKSKITFIDGDKGELLYRGYPIEQLAEQCNFLEVAYLLKNGELPNAEQK
                     TAFESTIKNHTMLHDQMTKFYSGFRRDAHPMAVMVGVVGALSAFYHEAMDFSDAQHRS
                     VSINRLIAKLPTIVAMAYKYNKGEPFMYPRNDLDYTANFMHMMFGTPCEKYEPNPVLV
                     RALDVIFTLHADHEQNASTSTVRLAGSSGANPFACISAGIACLWGPAHGGANEACLNM
                     LEEIGDVSRVSEYIARAKDKNDSFKLMGFGHRVYKNFDPRAKLMQKVCNEVLTELGLE
                     NDRLFKLAMELEKIALEDPYFVEKKLYPNVDFYSGIVQKALGIPTSMFTCIFALARTV
                     GWITQWEEMITDPEYKIGRPRQLYVGTARRDVPALAQRP"
     gene            28464..31313
                     /locus_tag="P5537_03685"
     CDS             28464..31313
                     /locus_tag="P5537_03685"
                     /EC_number="1.2.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004591 - oxoglutarate dehydrogenase
                     (succinyl-transferring) activity [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="HRV77176.1"
                     /translation="MMKQLEQTSHLFGSNAPFIEEQYENYLADPTSVSAEWRDYFDKL
                     QAQVGAAARDVPHGPVIAAFEQMAKRGPVRTVVTAGEDKQQVSVLQLINAYRFLGNRW
                     ANLDPLKRTERPQIAELEPSYYGFTEADLSKSFNVGSFHGFSTERATLREILEALRQT
                     YCGPIGAEYMYMTDIGQKRWIQSRLESLRGTPKFSAEMKKRILERTTAAETLERYLHT
                     RYVGQKRFSLEGGESAIVAMDELIRVAGSLGVQESVIGMAHRGRLNVLVNTLGKSPSM
                     LFSEFEGKAAADLTAGDVKYHMGFSSDVMTPGGPMHLTLAFNPSHLEIINPVVEGSVY
                     ARQVRRGDADKNQVLPVLIHGDAAVAGQGVNQEMLNFSQTRGYGTGGTVHLVVNNQIG
                     FTTSDPRDYRSSLYCTDIFKMVEAPIFHVNGDDPEAVALVTALAVEFRQEFKKDVVVD
                     IICFRKLGHNEQDEPMVTQPLMYRTIQKHPGTRKLYADRLVAEGTLKSDEPDQMIAEY
                     REHLDKGQLLYNPVLSGHNRQFAADWTPYIKQPYTDECDTTVPVQEIKRLSERLSTIP
                     ANFTLHSRVKKIIDDRAAMGRGEVPFDWGMGENLAYASLLAQGYGVRLSGEDVGRGTF
                     FHRHAVLHDQKRERWDEGIYKPLDHIQDGQARFQSYDSVLSEEGVLAFEYGYATTEPN
                     ELVIWEAQFGDFVNGAQVVLDQFISSGEAKWGRLCGLTLMLPHGYEGQGPEHSSARLE
                     RYMNNAAEQNWQICVPTTPAQVFHLLRRQAIRKVRKPLIIITPKSLLRHKEAISSIEE
                     LANGSFQTVIPEVEKLDAKKVKRVVLCQGKIYYELLAHRRENKITDTALVRIEQLYPF
                     PTEAFAKAIEQFPNAKEIVWAQEEPRNQGAWYWLASRQHLVNVLGTKRRLLLVSRPAA
                     ASPAVGYYAKHNAQQKAVLENAFGPIQDTTPQFPH"
     gene            31337..32530
                     /gene="odhB"
                     /locus_tag="P5537_03690"
     CDS             31337..32530
                     /gene="odhB"
                     /locus_tag="P5537_03690"
                     /EC_number="2.3.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045252 - oxoglutarate dehydrogenase
                     complex [Evidence IEA];
                     GO_function: GO:0004149 - dihydrolipoyllysine-residue
                     succinyltransferase activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="HRV77177.1"
                     /translation="MLIEVKVPQLSESVSEATLVTWHKKEGDAVARDENLIDIETDKV
                     VLETPAPADGVLVKIIKQGGDTVTSGELIAQIDTEAKAAAGAAAAAPAAAPAAAPAAA
                     PAASGAAGAASPAARKILDEKGIAAGDVAGSGRGGRVTKEDAVAAQPKAAAAAAPAAV
                     QLTGDRPEERVPMTRLRARIAERLIQSKNENAILTTFNEVNMAPVMALRKQYGDKFEK
                     AHGVRLGFMGFFVKAAVAALKKFPILNASVDGNDIVYHGYIDIGIAVGSPRGLVVPIL
                     RNAEAMSIAEIELKIAEFGQKAKDGKLSLDDLSGGTFSISNGGVFGSMMSTPIINPPQ
                     SAILGIHATKDRPVVENGQIVIRPINYLAMSYDHRIIDGREAVLGLVTMKEALEDPAR
                     LILDV"
     gene            32664..34088
                     /gene="lpdA"
                     /locus_tag="P5537_03695"
     CDS             32664..34088
                     /gene="lpdA"
                     /locus_tag="P5537_03695"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA];
                     GO_process: GO:0051068 - dihydrolipoamide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HRV77178.1"
                     /translation="MSKEFDVLVIGGGPGGYVAAIRAAQLGFKTACCESNPYADPKGE
                     PRLGGTCLNVGCIPSKALLHTSHLFEEAGHAFEGQGISVGTPKIDVPKMIARKSGIVD
                     QLTGGIKGLFKKNKVTLLNGHGAFMGKAEAGWQVQVGEELVVAKQVIVATGSAPRHLP
                     GVPVDNKIVCDNVGALDLDAVPKKLAVIGAGVIGLEMGSVWRRLGAEVTVLEAMPEFL
                     SLADQDVAKEALKVFTKQGLKFNLGVTIGEVKVGKKGVSIAYKDKDGADQKLEADRLI
                     VSVGRVPNTQGLNAEAVGLKLNERGQIEVDDHCKTNLPGVWAVGDVVRGPMLAHKAME
                     EAVMVAELMAGQAGHCNFDTVPWVLYTSPEIAWVGKTEQQLKAAGVAYKVGKIPFLAN
                     GRALGMGDSTGFVKMLADAATDRILGVHIIGANASELISEAVVAMEFAGCSEDLARIC
                     HAHPTLSEVVHEAALACDKRPLHF"
     gene            34192..35307
                     /gene="zapE"
                     /locus_tag="P5537_03700"
     CDS             34192..35307
                     /gene="zapE"
                     /locus_tag="P5537_03700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapE"
                     /protein_id="HRV77179.1"
                     /translation="MPHRILNVPQHGMIDAYEALLKTRGYQSDPAQRAAAQRLQGLYT
                     ELVGFKAARQGSRIKQFLNKPKMPRSVYFWGGVGRGKSFLMDCFYDSVPYRRKRRVHF
                     HAFMQEVQNDLRKFNNAPDPLQKVADRISEHTRLLCFDEFHVSDIADAMILGRLLDAL
                     FDRGVIFVMTSNYPPDGLYPNGLMRINFLPTIEKIKQRFDVIEVDHGTDYRLRTLEKM
                     EIYLVPHDDAAERKMAEDFRRLAASEGRGGSVEILGRNIDVVRQAPGVIWFDFASLCG
                     GPRSQNDYLEIAREHHTVILSNVPKMLVGNASEARRFTWLIDVLYDHRVKLIMSAAVE
                     AHDLYTEGHNAHEFVRTVSRLIEMRTRDYLAEPHRTE"
     gene            35522..37747
                     /locus_tag="P5537_03705"
     CDS             35522..37747
                     /locus_tag="P5537_03705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HRV77180.1"
                     /translation="MTHKLTAFLAFVFVIAMLGLTPAPGHAAEPASGSTSEQAGHQRL
                     ADLLEDEAARTALVEQLRKLGEEEAARAVESGAPTQTLAGQVAGLTQTVAQGVVSESA
                     AAVDALGVAWKQLAAADPQPLAWAAAEFVLLVAVTWIVFRLLSAAVGGIFRALDRYAG
                     ARDGPRALGWVRRSLALLGAAVLDLLIIGLSWLAGYGVALFVIGDTGSMRIQESLYLN
                     AFLLVELIRVALRVLLSGRGENLGILPIAAEDKAYWSAWASRMVFFVAYGLMLVVPVI
                     DHYLTPALGRAVFIAILLGAVLRAAVVVMQNRQRASQALEGLADRMQTPFGRIALTIG
                     ARIWHVVALVYLMAILVTSLLYPEQALPFMIAATGQTLLAVGLGIALAALLTQVILRR
                     IELGDELRLKFPLLEARLNAYVPSALKIARFVILAVVVAFIVDAWTPFDLGAWIASEA
                     GARVLGRALSVAVIVTLALLAWLVVASWIEFRLNPQAGMAPNPRARTLLTIFRNAIAI
                     ALVVVTTMVVLAEIGINIAPLLAGAGVLGLAIGFGAQKLVQDVITGVFIQLERAIDVG
                     DLVTAGGITGTVERMTIRSLGMRDMHGTYHLLPFSSVDTVSNYNRDFAFHVGEYGIGY
                     REDSDEAIVHLRAAFDELLADEAQRAQILDPVLDVHGVTALADNSVNIRVRIKTLPGG
                     QFGVGRAYNRLVKRHFDAAGIEIPYPQMTLHFGEDKQGKAPPARVCIEGEPVPLLAPG
                     R"
     gene            complement(37843..39780)
                     /locus_tag="P5537_03710"
     CDS             complement(37843..39780)
                     /locus_tag="P5537_03710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoX family phosphatase"
                     /protein_id="HRV77181.1"
                     /translation="MKKPDTLDDFPTNLSANEHFQSVVARAVSRRGFLKSGLGLSAAA
                     FLSGSLAACTSDDDASVAPSPSSPPAVATPLLSFEGIPTSTADDIVVAAGYTATVFAP
                     WGTPLFSSGPGSSWAGDASEGAAEQARQVGDNHDGLHFFPLTEGNNDEGLLVMNHEYT
                     NVRWLFANGQVDSLDDANKDLNAHGVSVIHIRRTAGRWEIVTDSAYNRRITGNTPMLL
                     TGPAAGDTLLQTNADPTGTLVFGTLNNCGNGYTPWGTYLTCEENFNQYFGTLNTLGTA
                     RNAAQVRYGLDSNGTERKYEQYVPRFDWQLEPNESNRFGWIVEIDPFDPRSTPKKRTA
                     LGRIKHENAAYRIGADGTVVVYMGDDQANDYVYKFVADGKYVAGDIRNNANLLDSGKL
                     YVAKFNDGAATGDFMGTGEWILLDKAANAALAGFANQAEVLVNTRLAADAVGATKMDR
                     PEWVAVHPKTCEVYVTMTNNSGRSVTDDANPRANNRFGQIVRWREAADDPAATSFEWD
                     LFVLAGNPTVHSDLRAGSSNVTAQNMFNSPDGLGFDKDGRLWIQTDGNYSNSGDFAGQ
                     GNNQMLCADPESKEIRRFFVGPKECEVTGLTFTPDSKTLFINIQHPGEGGNSNWPDGG
                     SARPRSATVIITKNDGGVIGS"
     gene            complement(39911..40657)
                     /gene="gspN"
                     /locus_tag="P5537_03715"
     CDS             complement(39911..40657)
                     /gene="gspN"
                     /locus_tag="P5537_03715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015627 - type II protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein N"
                     /protein_id="HRV77182.1"
                     /translation="MKFATGAAIFCAGLGVLLVASAPAVLLDAGLDRASAGRFRLALT
                     AGTLWNGQGRLASADSSASLSPITRLRWEFEPSALASVRLRWRLAIDGGTPGILEIGP
                     GGVALQRLALQLPPAVALAAVPHAIARAGWRGVLDVNVPALACTWSGRCEGGLQAEWS
                     AAGVDILPGQALGDHRMVATITAPATTLEITALRGLALAVNGKVELARGRRPRVELEI
                     GGNAPLLGRLEGMLAELRPTRDGERIQIRF"
     gene            complement(40654..41223)
                     /gene="gspM"
                     /locus_tag="P5537_03720"
     CDS             complement(40654..41223)
                     /gene="gspM"
                     /locus_tag="P5537_03720"
                     /inference="COORDINATES: protein motif:HMM:NF016493.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015627 - type II protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspM"
                     /protein_id="HRV77183.1"
                     /translation="MNAPSSSPTASGRSPAPSAAHSPTRPDTTSPTARLRAWYAARAT
                     RERRLLALAAAVVLGGGLIALAEHLVAERERLARSLPAARLAYLGMEQDSLGLAALRE
                     HPAPAANPPAAVPDSIRAAASARAIEVEARLVGERVEVDGRSTLPALIDWLAALHAEQ
                     RLRPSRLELQPVGSDGRARFDAEFEAGGR"
     gene            complement(41322..42497)
                     /gene="gspL"
                     /locus_tag="P5537_03725"
     CDS             complement(41322..42497)
                     /gene="gspL"
                     /locus_tag="P5537_03725"
                     /inference="COORDINATES: protein motif:HMM:TIGR01709.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015627 - type II protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspL"
                     /protein_id="HRV77184.1"
                     /translation="MTTTLMLLAGERWPQEPTADWVLLDAARRPLDRGRSDPRHWPAA
                     DRHELMLAGSRVLWLELELPPAPKREQPQLIRYALESHLARDPDQQHLTVSGRDPASA
                     RVGVLVVARSELATLVAACKALGRPLDALRSALQLAPPAPGQWTLAVLPGATAVLRTG
                     PRAGMALDADSADTLVEWLTLQLDATPAEARPIRLELRAAAGASPAEAAALAVRSGLE
                     VEEGPALDWWQPARDAVNLLHGEFAPAHGGDGWWPRLRKPAILAASAAGVWLLAQAAL
                     VWSDGREERALRERGEQLAAEALPGQPLLEPRMQLRRAHERALQAHGQLAAGDLLSLL
                     DAALEAGAPQPQALRYEEGRLTLELAGPPPAELLVRLDARGLAARAEGSRLILAARP"
     gene            complement(42494..43480)
                     /gene="gspK"
                     /locus_tag="P5537_03730"
     CDS             complement(42494..43480)
                     /gene="gspK"
                     /locus_tag="P5537_03730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004348222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspK"
                     /protein_id="HRV77185.1"
                     /translation="MSAPSSAFSRCARRTAQRGAAVVLALLTVSFAAMLAAAALADFG
                     HGLDMLGGRHDQAQAWQLGRAAVDWSRNILADDARRTPTDHLGEIWTTEIPVTAIGSD
                     VTDGSVGGAIRDLSGRFNLNELAPRGRVDTQAVTRFARLLGLVGMSGASANAAAQALA
                     AHLQGGAADAGAGRDARTATASEAPGGAETNAGGGRALVETRELVLLGLVPAATFNTL
                     EPHVVAAPAGAAININTASAEVLAAVLDGLSLDAARNLVAARERAWFRNLGDLQGRLP
                     EGAGLPAGRVLDVRSRYFLVTVTAAYGDAVLNLQAMLDRESNWPSILWYHTP"
     gene            complement(43443..44114)
                     /locus_tag="P5537_03735"
     CDS             complement(43443..44114)
                     /locus_tag="P5537_03735"
                     /inference="COORDINATES: protein motif:HMM:NF023044.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015627 - type II protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspJ"
                     /protein_id="HRV77186.1"
                     /translation="MPRGHLPVSPRAVPHRAARRRGVGLTLIELMVAMALLGVVGVLT
                     WRATSQLVDARERIGTELSRWQAVVHASALIERELMQIAPPQLAEGTGPSAATAGATL
                     PALELEGDPNGRRSRLAWTVIGGEQGFGRVELRHQDQRLEALVWPDREARGEVVRLPL
                     LDGVDTLRWRLLAAGQAHTQWPAAENRSRGRGRAAIVTPLPEAVEFTLELADVGTVVR
                     VLALR"
     gene            complement(44123..44545)
                     /gene="gspI"
                     /locus_tag="P5537_03740"
     CDS             complement(44123..44545)
                     /gene="gspI"
                     /locus_tag="P5537_03740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004389108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015627 - type II protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspI"
                     /protein_id="HRV77187.1"
                     /translation="MNPATHPARCGIRARPRDAGRARGFTLLESLVALAIVAIALVSA
                     LRAMGATAQSTAALREHTLASWVAQNRLAMHRATAAWPAIGEYRGEAEQARVKMRWEE
                     KVSGTPNALFRRIDVRVLDARGERTLATLSGFAVRPLR"
     gene            complement(44542..45096)
                     /locus_tag="P5537_03745"
     CDS             complement(44542..45096)
                     /locus_tag="P5537_03745"
                     /inference="COORDINATES: protein motif:HMM:NF019575.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HRV77188.1"
                     /translation="MQRGFTLVELLVVLVIVGIAGGGIALALDRAQADDSEREVERLR
                     RALEGAAYRAELRGRALAVELLPDGYRFSERQTDGGWKRLETPPELAPRAFAGGLRVA
                     ALRVGEQGGRQALRAGSEDAYSAGALAGESPATPLDGGGRRIVFGSRAPAFELDLAED
                     GKRYRIAGRIDGRMERLAGAEPAR"
     gene            complement(45131..45589)
                     /gene="gspG"
                     /locus_tag="P5537_03750"
     CDS             complement(45131..45589)
                     /gene="gspG"
                     /locus_tag="P5537_03750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004389964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015627 - type II protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system major pseudopilin GspG"
                     /protein_id="HRV77189.1"
                     /translation="MQQRFARPARVDRPAHRSRGFTLIEVMVVIVILGVLAALVVPRI
                     MSRPDEARVVAARQDIASLMQALKLYKLDNRRYPSTEQGLGALVVRPSAAPAPENWKA
                     YVERLPADPWGQPYQYLAPGVHGEVDVFSYGADGRPGGEGFDADIGSWQP"
     gene            complement(45594..46826)
                     /gene="gspF"
                     /locus_tag="P5537_03755"
     CDS             complement(45594..46826)
                     /gene="gspF"
                     /locus_tag="P5537_03755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015627 - type II protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system inner membrane protein
                     GspF"
                     /protein_id="HRV77190.1"
                     /translation="MSAFRYRAFDLQGTPSTGVIEADSGRAARSALRERGLHPVEVID
                     LGQQARAAAGRPGWLARVQARRRLPVNELALLSRQWATLLAAGLTVEHSLSALIEQAE
                     SERVHDTLAAIRSDVVSGHSLRIALDRHSGAFPPIYRAAIAAGEQSGELAAVMNQLAD
                     HLERGADLQRKTMQALIYPALVAVVALLVVTGLMVFVVPQVVGVFAQSKQALPLLTRI
                     MIGTSNFIRDWGWLALAAGPAALLGALALLRDERIRHAFDRRLLALPVLGRHLRSLDA
                     TRFASTLAILVGSGVPLLAALDAAGRVVQRLPIRAAVREAAEQVREGRPLARALAAGR
                     AFPPMLIHMVANGEATGRIDQLLDRAARLQQQELETRTATLTSLLEPLLLLVMGAVVL
                     LIVLAVMQPIIEINTLMR"
     gene            complement(46837..48261)
                     /gene="gspE"
                     /locus_tag="P5537_03760"
     CDS             complement(46837..48261)
                     /gene="gspE"
                     /locus_tag="P5537_03760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015627 - type II protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system ATPase GspE"
                     /protein_id="HRV77191.1"
                     /translation="MGFELPYGFARDHGVLVAALGAEHAEVLVREDARPQALAEVRRS
                     VGLPLRLQRVPRAEFDARLAEAYGGAGGSAAEVVADVGQEVDLDRLMTELPAVEDLLD
                     TQDDAPIIRLINALLTQAVRDGASDVHIEPYERESVVRLRRDGVLRDIARPRRGLHAA
                     MASRIKIMAQLDIAEKRLPQDGRITLRLAGRAVDVRVSTVPTTHGERLVLRLLDKQAG
                     RIGLDGLGMAPTTGAAFTELLGQPHGILLVTGPTGSGKTTTLYAALQSLDAARLNIVT
                     VEDPVEFDLPGVGQIAVNPRIELDFARALRAILRQDPDVIMIGEIRDLETAQIAIQAS
                     LTGHLVLATLHTNDSAAALTRLVDMGIEPFLLASTLRGVLAQRLVRKLCPDCRQPATT
                     MQGWEAGQCGHCGHSGYRGRAGIYELLVVDEALRRLIHDGADEDRLRTHARAAGMRSL
                     HEDGLRHVASGLTSAAELQRVIRA"
     gene            complement(48261..>50323)
                     /gene="gspD"
                     /locus_tag="P5537_03765"
     CDS             complement(48261..>50323)
                     /gene="gspD"
                     /locus_tag="P5537_03765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015627 - type II protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="type II secretion system secretin GspD"
                     /protein_id="HRV77192.1"
                     /translation="AHAAGEPVALNFQNAEIDSVIQAIGRISGRNFLIDPRVKGKINL
                     ITNTPVAPELTYQILLSALRLQGYAAIEESGVTKLVPEADAKLHGVPVVSGRQGAGGA
                     RGDRLVTQVFALRHESAAHMVNVVRPLVSANNAVTAFPGNNTLVVTDYAENLRRLATV
                     IDSIDTPQGDVAVLHLQHAMANDLAPVLVRLLAEQQAGGQNAGGLAPPQIVAEPNSNS
                     LLVRADTPSRLAALRQLVIALDRPGAGGDIRVVYLRNADATQVAATLNAALAGEGGTS
                     EAATTQPLSRNGGGGFGTGSSAASGMGVASAPLRGTGAATSTTAGGLSSATRGGMVQP
                     DAVNNALIITAPDAVYRNLRAVIDQLDRRRAQVYIEALIAEISTERAAEFGFQWVGGG
                     ASGKVGILGGQIFNSGGSNLGQLIAGTSGNGTPTLPNNGLNLVVGGGKVNVPGLGEVL
                     SLGVLARFLENEVSANILSTPNLITLDNEEARIVVGRNLPFVTGQYANTGGGTTPANP
                     FQTIERRDVGLTLHVKPQISEGGTIRLQIYQEASAVVGSAESAAAGNSVTTKRSIESM
                     VLVDDGAILALGGLVEDSYSGGEEKVPVLGDLPIAGSLFRYDTRKRSKTNLVVFLRPV
                     ILRDRDSYAALTDSRYDYVIGRRDELPSGSNLLRDPPPGEPAPVVDLAFRPLQRAASP
                     VAPR"
BASE COUNT         7849 a        16854 c        17613 g         8007 t
ORIGIN      
        1 cggcagccgc gaatgcggcg gtgcaggggg tgacgaggcc gcgggtgatc gacgccgcct
       61 tcgcgcctgc cggcgctcct acatgaaccg ccacgcgccc gcagcccctg taggagcggc
      121 ggcagccgcg aatggggcgg tgcagggggt gacgaggccg cgggcgttca ggcgggggcg
      181 cgggggcggg tggtttcggc gcggatctcg tgaaggagct cgatcttgcc gtcatcgcct
      241 gcgcgctcca ggcgtacggt gaagccccac aggcgggcga ggtggcgcat gacctcgtcg
      301 gtgccgtcgc cgagcgggcg gcggcggaag gcggtgtggc gcagggtgag cgagcggtcg
      361 ccgcgcaggt cgacgttcca gacctgcacg ttgggctcgc gtgcgcccag gttgtactgg
      421 tcggagagga tctcgcgcag cttgcggaag cccgcgtcgt cgtggatcgc ggagacctgc
      481 agcttgtcct cgtggtcgtc gtcgagcacg gcgaacaggc ggaagtcgcg catgaccttc
      541 ggcgacaggt actgcgcgat gaagctctcg tccttgaagt tgcgcatcgc gaagtcgaag
      601 gtctccagcc agtcgctgcc ggcaatctcg gggaaccagc gccggtcttc ctcgtccggg
      661 tcctcgcaga tgcggcgcag gtcgcgccac atcgcgaagc cgagcgcgta ggggttgatg
      721 ccactaaacc agcggctgtt gtagggtggc tgggcgacga cgttggtgtg cgactgcagg
      781 aactcgagca tgaagctgtc ggcgagcagg ccctcgtcgt agaggtgatt gagcagggtg
      841 tagtgccaga aggtcgccca gccctcgttc atgacctggg tctggcgctg cgggaagaag
      901 tactgcgcga tcttgcgcac gatgcgcacc acctcgcgct gccagggctc gagcaggggg
      961 gcgttcttct cgacgaagta gagcaggttc tcctcgggct cgggcgggaa gcgcgcctcg
     1021 gcgcgggcgt cggcgcgcac gtcgtgtgcg ggcagggtgc gccagaggtc gttcacctgg
     1081 ctctgcaggt attcctcgcg ctcctgctgg cgcagcttct ccttggcgag cgagagcctg
     1141 ggcgggcgct tgtagcggtc gacgccgagg ttcatcaggg cgtggcagga atcgagcagc
     1201 agctcgacgg cctcctcgcc gtgacgctcc tcgcactggg tgatgtagtt ccgcgcgaac
     1261 agcaggtagt cgatgatggc gtcggcgttg gtccaggtgc ggaacaggta gttgcccttg
     1321 aagaagctgt tgtggccgta ggcggcgtgg gcgatcacca ggccctgcat ggtgagcgtg
     1381 ttctcctcca tcaggtaggc gatgcagggg ttggagttga tcacgatctc gtaggccagc
     1441 cccatctggc cgcgccggta gcccttctcg gtggcgagga agtgcttgcc gaaggaccag
     1501 tggtggtaat tgaccggcat gcccaccgag gcgtaggcgt ccatcatctg ctcggcggtg
     1561 atgatctcga cctgcaccgg gtagatgtcg agcttgtagt gcgcggcgac gcgggcgatc
     1621 tcgtcgttgt agcggtcgat ggcctcgacg gtccattccg agccggaggg gagcggcgac
     1681 ttggcggcgc ggccgcgcgt gcgggggcgg gtggtcttca tgcgagggtc ttcttgaaca
     1741 gttcgcggaa caccgggtag atgtcggccg gcgactcgat gcgctgcatc gcgaagttgt
     1801 cgtgcgcggc ctcgagcttg gcgtactcgc gccacagatt ctgcggctcg ccggcggtga
     1861 tctcgacgta ggcgaagtac tggcaccacg gcaggatctc cttgccgagc aggcgcccgc
     1921 acaccggcga gtcgttgtcc cagttgtcgc cgtcggaggc ctgggcgccg tagacgttcc
     1981 actgcccgtt ggcgtagcgc tcgcgcagga tgccgcgcat gagctcgagc gcgctggaga
     2041 ccacggtgcc gccggactcg cgcgagtgga agaactcgtc ctcgtcgacc tccttggcca
     2101 cggtgtggtg gcggatgaag acgacctcga tgtgctcgta gctgcgcgtg aggaagaggt
     2161 agagcagcat gaagaagcgc ttggccatgg acttgcgctc ctcgtccatc gagccggaga
     2221 cgtccatcac gcagaacatc accgcctgcg tggtggggcg gggctccttg atgcggttgt
     2281 tgtagcgcag gtcgaagcgg tcgatgaagg ggatgcggtc gatgcgcgcg cgcagcgcgg
     2341 cgagttcctc gcgcaggccg cgcacctcct cgctgtcctc gccgccgcgt gcgagcgcct
     2401 cgtcgagttc ctgctgcagc tcgcggatgc gcgcggccca gggcgagccg agcgccagtc
     2461 tgcgcccgag cgcgccgcgc atcgagcgca cgatgttgat gttggcgggc acgccgtccg
     2521 aggtgaagcc ggcgcgccgg gtcttgtagt cggtgacctt ggcgagctgg gtgcggatca
     2581 ggcgggggag ctcgaggtcc tcgaagaaga ggtcgaggaa ctcctcgcgc gagagctgga
     2641 agacgaagtc gtcctcgtgc tcgccgtcct ggctcgcctt gcccttgccg gcgccgtcgc
     2701 caccgccgcc gagcggacgc ttgatgcggt ctccggtgct gaactggtcg ttgcccggga
     2761 agacctgctc ccacacgccg cccttgccgt ggtgcagcga gggctcggag aggtcgcgcg
     2821 cggggatgga gatctgctcg ccgttctcca ggtcgcggat ggagcggcca tggatggcct
     2881 cggacaccgc cttgcggatc tgctgcttga agcggcgcat gaagcgctgg cggttgaccg
     2941 cgctcttgtt cttgctgtcg aagcgccgat cgatgatgcg gaccatgtct cctcccggtg
     3001 tccgcgcccg gcccgggccc gcgccacgag ggcgcgggcc gggccggacc gtggctcatg
     3061 aatcaggacg ccttgcgtac gcgcaggtac cactcgcaca gcaggcgcac ctgcttctcg
     3121 gtgtagccct tgtcgatcat gcggtcgacg aagtcctggt gcttcttctg ctcgtcggcg
     3181 ctggccttgg cgttgaagct gatcaccggc agcaggtcct cggtgttgga gaacatcttc
     3241 ttctcgatca ccgcgcgcag cttctcgtac gaggtccagc tcgggttgcg gccctcgtgc
     3301 ttggcacgcg cgcgcagcac gaagttgacc acctcgttgc ggaagtcctt cgggttgctg
     3361 atgccggccg gcttctcgat cttctccagc tcctcgttga gcgcggcgcg gtcgaggatc
     3421 tcgccggtgt tggggtcgcg gaactcctgg tcctggatcc agaagtcggc gtagatcacg
     3481 tagcggtcga agatgttctg cccgtactcg gagtagctct cgaggtaggc ggtctggatc
     3541 tccttgccga tgaactcggc gtagcgtggc gcgaggtatt ccttgatgta gccgaggtag
     3601 cgcgcctcgg tctcggccgg gaactgttcg gcctcgatct gctgctcgag cacgtacatc
     3661 aggtgcaccg ggttggcggc gacctcgcgg tggtcgaagt tgaagatctt cgacaaggcc
     3721 ttgaaggcga agcgggtcga caggccggtc atgccttcgt ccaccccggc gtagtcgcgg
     3781 tactcctggt agctcttggc cttggggtcg gtgtccttga ggttctcgcc gtcatacacc
     3841 cgcatcttgg agaagatgct ggagttctcg ggctccttga gccgcgacag caccgcgaac
     3901 tgggccatca tcttgagcgt gtcgggcgcg cacggcgcct cggacagcga gctgtgggcg
     3961 agcagcttct cgtagatccg cacctcgtcg gagacgcgca ggcaataggg caccttgacc
     4021 gtgtagatgc ggtcgaggaa ggcctcgttg ttgcggttgt tcttgaaggc gacccactcg
     4081 gattcgttgg aatgcgccat cacgatgccg tcgaagggga tggcgccgaa gccctcggtg
     4141 cccttgtagt taccctcctg ggtggcggtg agcagcgggt ggagcacctt gatcggcgcc
     4201 ttgaacatct cgacgaactc gagcaggccg cggttggcaa ggcacaggcc gcccgagtag
     4261 ctgtaggcgt cggggtcgtc ctgcgagtac tgctcgagct tgcggatgtc gatcttgcca
     4321 accagcgagg agatgtcctg gttgttctcg tcgcccggct cggtcttcgc gaccgcggtc
     4381 tggcgcagca ccgaggggct gagcttgacc acgcggaagc gggtgatgtc gccgccgtac
     4441 tcgtgcaggc gcttgaccgc ccacgggctc atgatgccgc cgaggtagcg gcgcgggatg
     4501 ccgaagtcgc cctcgaggat gtgcgcgtcc tcggcggcgt tgaagaggcc gagcggggac
     4561 tcgttcaccg gcgatccctt gatcgcgtag aagggcacgc gctcgatcag gctcttgagc
     4621 ttctcggcga gcgaggactt gcccccgccc accgggccga gcaggtagag gatctgcttc
     4681 ttctcctcca ggccctgcgc cgcgtggcgg aagtaggaca cgatgttctc gatgacctct
     4741 tccatgccgt agaaatcgcg gaaggccggg tagagcttga ggatcttgtt ggagaagatc
     4801 cgcgacaggc gcgggtcgag ccgggtgtcg accagttccg gttcgccgat cgccgcgagc
     4861 atgcgctcgg cggcggtggc gtaggccatg cggtcggtgc ggcagagctc gagatagtcc
     4921 tgcagggaca tctcttcctc gcgggccgct tcgaagcgtg cctggtaggc gttgaagatg
     4981 gacatggtcg tctcctcgtc gggcgcaatg cggcgcgaaa ggggctgccg caaggtgaag
     5041 caggatcgcg tcttccgcct gctcggcggt gcccggctcg ccttcacggg gtgccgggtc
     5101 tgtacatgag aaccccatga tgggtgggag ttccacccct cgcggcgctt tttcgtgagc
     5161 ggacgtggac tccgtcacgt cccgcgtcgg ggcgctctcc ggggctgttc tcgggggacg
     5221 ggacaagcgc agtgcctgtg ctagaatgcc cgactcagtt cattgtgctc acgctggcta
     5281 ggtgcgcctc cggtccccgc gagtgtgccg caagcgcccg gcgggagcgt ttttcagact
     5341 tctcaggatc gactcaatgg agcagaacca ggtaaccccg agcgcgctcg agcgccgtat
     5401 cgacatctcc gtttcgctcg cggacatcga gaaagaggtg gatgcccgcc tcaagcgcat
     5461 ggcgcgcacg gtgaagatgc cggggttccg cccgggcaag gtgccgatga agatcgtcgc
     5521 ccagacccat ggcggccagg cccgcggcga ggccgtcggt gcggcggtcg agaaggcctt
     5581 cggcgagaag gtgcgcgccg acaacctgcg tgtcgccggc tatccgagca tcgagccgaa
     5641 ggatggcgcc gccgagggta cgctggaatt caccgccgtg ttcgaggtgt accccgacgt
     5701 ggtggtgggc gagttcgccg gtcgcaagat cgagcgcccg gtgctgaacg tgggtgacgc
     5761 tgaggtcgac aagaccatcg aggtcctgcg caagcagcgc accggcttca aggcggtcga
     5821 gcgcgccgcc gccgcgggcg accgcgtcgt gatcgatttc accggtcgca tggacggcga
     5881 ggtgttcgac ggcggccagg cccaggactt ccccttcgtg gtcggcgcgg gctccatgct
     5941 caaggacttc gaggatgccg tggtcggtct cgcagccggc gagggcaaga ccttcgacat
     6001 gaccttcccc gaggactacc atgccgccaa tctggccggc aagcaggtcc agttcgagat
     6061 caccgtcaag gcggtcgagg agccggtgct gcccgaggtc gacgccgact tcgcgcgctc
     6121 gctgggcgtg gccgacggcg acgtcgccaa gctgcgcgag gaggtcaagg gcaacctgga
     6181 gcgcgaggtc aagcgtcgca tccagtcccg cctcaaggag caggtcatgg acgcgctgat
     6241 cgaggtcgcc ccgatcgacg tgcccaaggc gctggtgcag gccgagtcca accagctcgc
     6301 cgacaacgcc cgccgcgacc tcgagatgcg cggcctcaag accaaggaca tcccggtcga
     6361 tccgtcgtgg ttcaaggacc aggccgagcg ccgcgtcaag ctgggcctga tcatggccga
     6421 gctggtcaag gccagcgagc tgcacgccaa gcccgagcag atccgcgccc tggtcgagga
     6481 gatggcgcaa agttacgagg atccttcgga actcgtgcgc tggtattacg ctcaaccgga
     6541 gcgtctggcg caggccgagg cggtggtcat cgaagacaac gtcgtcgagt gggtctgcgc
     6601 caaggccgac acttccgaca aggaagtggc gttcgacgaa ctgatgggca acgcggcctg
     6661 aggtcgcaga gggtctgacg aatgatgcaa ggaacacccc agcacagcag cgactggaac
     6721 ccggtcggtc tcggcctggt cccgatggtg gtcgaacaga gcggtcgcgg cgagcgcgcc
     6781 tacgacatct attcgcgcct tctgaaggag cgggtggtgt tcctcgtcgg cccggtcaac
     6841 gacgtcaccg ccaacctgat cgtcgcccag ctgctcttcc tcgagtccga gaatccggac
     6901 aaggacatct acttctacat caactcgccc ggcggctcgg tgaccgccgg catggcgatc
     6961 tacgacacca tgcagttcat caagccgaac gtcagcacgc tgtgcatcgg ccaggcggcg
     7021 agcatgggcg ccttcctgct ggcggcgggc gagaagggca agcgcttcat cctgcccaat
     7081 tcgcgcgtga tgatccacca gccgctcggc ggcttccagg ggcaggcctc ggacatcgag
     7141 atccacgctc gcgagatcct ctacctgcgc tcgcgcctca acgacatgct gtccaagcac
     7201 accgggcagc cgctcgagcg catcgagaag gacaccgatc gcgacaactt catgtcggcg
     7261 acggcggccg tcgagtacgg cctggtcgac aaggtgctga ccagccgcga cgacacctga
     7321 tttctggaga acccccacat gacggacaag aaggctggcg gcgagaagct gctgtactgc
     7381 tccttctgcg gcaagagcca gcacgaggtg cgcaagctga tcgccggccc ttcggtcttc
     7441 atctgcgacg agtgcatcga gctgtgcaac gacatcatcc gcgacgaggt cgtcggtgcg
     7501 gagggtggcg aggggatcaa gggcacgctg cccaccccgc acgagatctg ctcgatcctc
     7561 gaccagtacg tgatcggtca gtcgctggcg aagcgtagtc tcgccgtcgc ggtgtacaac
     7621 cactacaagc gcctgcgcca catcgatgcg cgccaggacg acgtcgagct tgccaagagc
     7681 aacatcctgc tgatcggccc tactggttcg ggcaagaccc tgctcgcgca gacgctcgcg
     7741 cgcctgctcg acgtcccctt cgtgatggcc gacgcgacca cgctgaccga ggccggctac
     7801 gtcggcgagg acgtcgagaa catcgtccag aagctgctgc agaagtgcga ctacgatgtc
     7861 gacaaggcgc agcagggcat catctacatc gacgagatcg acaagatctc gcgcaaggcc
     7921 gacaacccct cgatcacccg cgacgtgtcg ggcgagggcg tgcagcaggc gctgctcaag
     7981 ctggtcgagg gcacggtcgc gtcgattccg ccgcagggcg ggcgcaagca cccgaaccag
     8041 gacttcatcc aggttgacac caccaacgtg ctgttcatct gcggtggcgc cttcgacggc
     8101 ctcgagaagg tcatccgcaa ccgtaccgag aaggtcggca tcggcttcgg cgccgaggtc
     8161 aagagcaagg aaggcaagaa cctcaccgat accttccgcc aggtcgagcc ggaagatctg
     8221 atcaagttcg gcctcatccc cgagctgatc ggccgcctgc cggtggtcgc aaccctgcag
     8281 gaactcgacg aggcggcgct gatccagatc ctcatcgagc ccaagaacgc gctggtcaag
     8341 cagtaccaga agctgttctc gatggagggc gtcgagctcg agatccgtcc caacgcgctg
     8401 cacgccgtgg cgcgcaaggc gatcaagcgc aagaccggtg cgcgcgggct gcgctccatc
     8461 ctcgaggtgg cgctgctcga catcatgtac gacctgccga cgctcgacga cgtcgccaag
     8521 gtggtggtgg acgagtccac catcgaggac ggcggcaagc cgctgctgat ctatgccgag
     8581 caacagaagg tgtcgggcgc caactgagcg cggcgtacca ccaccaccgc ccgatccggc
     8641 gacgccggct ccgtccggcc ggccgcttga atttccgggt cacgccctca catgggtgtg
     8701 accttttgct tgaggaaacc tagaaaatgt cgggtcacgc tgccctcccc aacgaagcga
     8761 tggaactgcc gctgttgccc ttgcgcgacg tggtggtctt cccgcacatg gtgatccccc
     8821 tcttcgtcgg ccgcccgaag agcatcaagg cgctcgagag cgcgatggaa gacggcaaga
     8881 gcatcctcct cgtggcgcag aagtccgccg cgaaggacga acccgcggtc gaggatctct
     8941 acgacatcgg ctgcatcgcc aacatcctgc agatgctcaa gctgcccgac ggcaccatca
     9001 aggtgctggt cgagggtgtg cagcgcgcgc gcatcgagcg cgtcgaggac atgcgcagcc
     9061 tgttcgtcgc cagcgtgcgc ccggtgccgg tcgccgaggc gcccagccat gagctggagg
     9121 ccatgcggcg ggcgatcatc gcccagttcg accagtacgt taagctgaac aagaagatcc
     9181 cgcccgagat cctcggctcg ctcgcgggca tcgaggaggc cgggcgcctg gccgacacca
     9241 tcgccgccca cctgccgctc aagctcgagc aaaagcagga agtgctcgag atgttcgaca
     9301 ccggcgcgcg cctcgacaag ctgctcggcc agctcgaggg cgagctcgac atcctccagg
     9361 tcgagaagcg catccgcggc cgcgtcaagc gccagatgga gaagagccag cgcgagtact
     9421 acctcaacga gcaggtcaag gccatccaga aggagctcgg cgagggcgag gagggtgccg
     9481 atctcgagga gatggacaag aagatcaagt ccgccggcat gcccaaggaa gcgctggcga
     9541 aggccgaggc cgagttcaag aagctgcgcc tgatgtcgcc gatgtcggcg gaagcgaccg
     9601 tggtgcgcaa ctacatcgac accctgatcg gcctgccgtg gaagaagaag tcgcgcgtca
     9661 gcaaggatct tggcgaagcc gagaaggtcc tcgacaagga ccactacggc ctcgagcgcg
     9721 tcaaggaacg catcctcgag tatctcgccg tgcagcagcg cgtggacaag gtcaaggcgc
     9781 cgatcctgtg cctggtcggc cccccgggcg tgggcaagac ctcgctcggc cagtcgatcg
     9841 ccaaggccac caaccgcaag ttcatccgca tggcgctcgg cggcgtgcgc gacgaggccg
     9901 agatccgcgg ccaccgccgc acctacatcg gttcgatgcc cgggaagatc ctgcagaaca
     9961 tgagcaaggt cggggtcaag aacccgctct tcctgctcga cgaggtggac aagctcggca
    10021 tggacttccg tggcgatcct tcgtcggcgc tcctcgaggt gctcgacccg gagcagaacc
    10081 acaccttcca ggaccactac gtcgaggtcg atttcgatct ctccgacgtg atgttcgtcg
    10141 ccaccgccaa cacgctcaac attccgccgg cgctgctcga ccgcatggag gtgatccgcc
    10201 tgtcgggtta caccgaggac gagaagatca acatcgccca gcgctacctg ctgcccaagc
    10261 agatgaagaa caacgggctc aagcgcgagg agctgtcggt caccgaggaa gcggtgcgtg
    10321 acgtcgtgcg ctactacacg cgcgaggccg gcgtgcgcag cctcgagcgc gagatctcca
    10381 aggtctgccg caaggtggtc aagcagctcg tgctcaagag ccgcacgagc aaggtggtcg
    10441 tcaacgcgaa gaacctcgac aagttcctcg gcgtgcgcaa gtacagcttc ggcatggccg
    10501 agaaggagaa ccaggtcggc caggtcaccg gtctcgcgtg gaccgaggtc ggcggcgagc
    10561 tgctgaccat cgaggcggtg cagctgcccg gcaagggcaa ggtggtcacc acgggtaagc
    10621 tcggcgaggt gatgcaggag tccatccagg ccgcgctctc ggtggtgcgc cggcgcgcgc
    10681 gctcgctcgg catcgacccg gacttctatc agaagagcga cctgcacatc cacctgccgg
    10741 aaggcgcgat ccccaaggac ggaccgtcgg cgggcatcgc gatctcgacc gcgctggtgt
    10801 cggtgctcac cggcattccg gtgcgttgcg acgtggcgat gaccggcgag atcaccctgc
    10861 gcggcgaggt gctggcgatc ggcggtctca aggagaagct gctggctgcg gtgcgcggcg
    10921 gcatccgcac cgcgctgatc cccgaggaga acgtcaagga tctcgccgag atccccgaca
    10981 acatcaagaa cgccatcgag atcgtgccgg tgaagtggat cgaccgcgtg ctcgagctcg
    11041 ccctcgaacg caagcccgag cctctgcccg aggagcccgc tccggcggcg ccggccacac
    11101 cggcggccga aggtgcggaa ggcgacaagg cgaacctgcg cccgcattga tttgtcccgg
    11161 cctccgggcc ggtgttgcat ccaggaaaag ccgtgctgcc cccagggtgc agcacggctt
    11221 ttccgttttg ctcgggtgtg cgctcaggcg cctgccacgg tgtcctccac cggcagtccc
    11281 catgcgcgcg cgacgagctc caacgagcgc aggcgggcgc cgtggtcgaa gatctgcgcg
    11341 gtgaggatca gctcgttcgc tccggtacgc tcgatcaggg tctccagctg ctggcgcacg
    11401 gtgtcggggg cgcccactgc cgagcaggcg agcgactgct cggcgaaggc gagctcggag
    11461 gtagaccaat cggtgtcgac gaaggcctcc ggaggctgca gctgcccgcg caccccgcgt
    11521 gccatcgcgg cgaagcgcag ctgcagggag cgcagcaggt actccgcctc ggcgtcggtg
    11581 tcggcggcga tcgcgttggc ggcaaccgcg aaccagggct tgtcgagctg ggcggaggga
    11641 cggaagttgc tgcggtagag gtcgaccgcc tcgaacagga agcgcggtgc gaagtgcgag
    11701 gcgaaggcga agggcaggcc gagccgggcg gcgagttcgg caccgtagaa gctcgagccg
    11761 agcagccaca gcggcacctg cagcccttcg ccgggcaccg cgcgtacggc ctgcccgggc
    11821 ccggccggct ggaagtagga ctgcagttcg agcacgtcct gcgggaagtg gtcgtcgctg
    11881 ccgaccagat tgcgccgcag cgcgcgcgcg gtggtctggt cggtgcccgg agcacgtccg
    11941 aggccgaggt cgatccggcc aggaaagagc gactccaggg tgccgaactg ttcggcaatg
    12001 accagcggtg catggttggg cagcatgatg ccgccggcgc cgacgcggat gcggcgggtc
    12061 gcgccggcga tgtgtccgat caccaccgcg gttgcggcgc tggcgatgcc ggtcatgttg
    12121 tggtgttcgg cgagccagta gcgggtatag ccgcagcgat cggcgagctg ggcgagttcg
    12181 cgcgtgttgc gcagcgcatc tgccggcgtg ctgccggcgg tgatcggtgc gagatcgagc
    12241 accgagagcg ggacggagga gggcatggaa gtatcacttg gagccgggcc tttcattacg
    12301 ccacagagct gcggtgcgtg ccagcatgga gcgcgcgcca gcaggcttgc acggcgtgat
    12361 acgcttgacc gggtcgggtt gcaggtgtct gttgcggcgc gcgagctacc cgtaacgggc
    12421 gcacatcgcg gaatacggta attgaggcga agggtttttt ttgacaccat tcggcccctg
    12481 cggaattgcc ggtcgatccg ctgctttgcc cgagacccat gcggcaaggg cgcgaagaag
    12541 ccaacaacaa accaatcgag gagttctgga tgaaaaaata cgcccttctg tgcgcagtgc
    12601 ttgcccttca cgccggtgcc agtttcgcca aggactggaa cgagatccgc atggcgtccg
    12661 aaggcgctta tcccccgttc aacaccacca cggccgacgg cagcatggcg ggcttcgaca
    12721 tcgacatcgg caacgccctg tgcgaagaga tgaaggcgaa gtgcacctgg gtgaagcagg
    12781 aatgggacgg catgatcccg gcgctggtct cgcgcaagtt cgacgccatc atcgcctcga
    12841 tgtcgatcac cgaggaacgc aaggccaagg tcgacttcac cgacaaatac tatgcctcgc
    12901 cgctcgccct gatcgcgaag aagggctccg agctgcgtcc cgacctcgag ctgctcaagg
    12961 gcaagaaggt cggcgtgcag cgcggtacgg tgtcggacaa cttcgccacc aagtactggg
    13021 acggcaaggg tctgcagatc gtgcgttacg ccaagcagga cgaggcctac ctcgacctgc
    13081 gtgccgggcg cctggatgca gccttcgtcg actatctcga ggcctacggc ggtttcctga
    13141 ccaagcccga gggcgagggc tacgacgtgg cgggcgatcg cctgttcggt cgcaatgccg
    13201 aggagaaggc ggtgatcggc gagggcatcg gcatcgcggt gcgcaagcgc gacaaggaac
    13261 tcaccgagaa gctcaaccag gccctcgcgg cgattcgtgc caacggcaag tacgacgcga
    13321 tccagaagaa gtacttcccg atggacatct acggcaactg atcgccctga tcgaccgcgg
    13381 ccgcgttcgt gcgggccgcg gcctttccct gccgcgcgct cgcctgagcg ggggcgtgcg
    13441 cgtctttcac tccgaatcgg tgcgccatgg atgccctgat cgaatactcc cccagcctgc
    13501 tcgccggcgc ctgggtcacg ctcaaggtgg cgctggtgtc ggtgctgctc gcgctggtga
    13561 ccggcctgat cggggccgcc tgcaagctgt cgggtttcct gccgctgcgt ttgtggacca
    13621 tgctctacac cacggtgatg cgcggcgtgc ccgatctggt gatgatgctg ctggtgtttt
    13681 atggcgggca ggtgctgctc aacctcgtca tcgaccactt cggctgggac ttcatcgaga
    13741 tcgacccctt cgtggccggc gtgctgacga tcgggctgat cttcggcgcc tatttcaccg
    13801 agaccttccg cggcgccttc ctcgccgtgt ctgcgggcca gctcgaggcc gggcgcgcct
    13861 acggcatgag cacctggcag gtctttcgcc gcatcctgtt cccgcagatg ctgcgcttcg
    13921 ccctgccggg catcggcaac aactggctgg tgctgctcaa gagcaccgcg atcgtgtcca
    13981 tgatcggcct ctccgacatg acgcggatcg ccgaccaggc cgggcgctcg acgcaccagc
    14041 ccttcacctt ctatctcgcg gtctgcgtgc tctacctggc gatgaccgcg ctgtcgagct
    14101 acggcctcgg cgtgctcatg cggcgctaca gcgccggtgt gcgcgagacc caggtctgag
    14161 gggggcgccc atggaactct tcgacctcag cgtcatcacc ggcagcctgc cccagttctg
    14221 gcgcggcctg tggatgaccc tccagctcac cggcttcgcg ctgctgttcg gtttcttcgc
    14281 ggcgatcccg cttgcggttc tgcgcctgtc ccccaatcgc ctcgtggcgg ccccggtcgc
    14341 cgcctacacc tacttcttcc gcggcacgcc gatgctggtg cagttgctgc tggtgtatta
    14401 cggcgcctcg cagtgggaat ggatgcgcgc agcctgggag gccgggcatc cggtgtggac
    14461 gctgttccgc gagccctact tctgcgcctt gttcgccttc ggcctcaaca cctgcgccta
    14521 caccgtagag atcctcgccg gcagcatgcg caacaccccg cacggtgagc tcgaggcggc
    14581 caaggcgatg ggcatgacgc ggttgaaggc gctgcagcgc atcgtgatcc cgtcggcgct
    14641 gcggcgcatg atccccgcct acagcaacga agtgatcctg atgctgcagg gttcggcgat
    14701 cgccagcgcg gtgaccctgg tcgacctcac cggcgcggcg cgcgatgtgt attcccgcca
    14761 cttcgcgccc ttcgaggcct tcgtcttcgt cggcctgatc tacctcgcgc tcaccttcgt
    14821 gctggtgggc ctgttcaagc tcgcagagca ccgctggctc gcccacctgg cgcctcgcaa
    14881 ggcggaggcg ggaaggcagt cctgatcaac cccgccgcga gtgctgcgcc cccaccgtcg
    14941 ccgatccgcg gcgatgccga gcgctaaccc gcggcgacac gccgggcgcc tcgcaggccc
    15001 ccaagcaaga gaacaacatg aaccacaagg ccagcgtcga acaggtccgc gtcgaagacc
    15061 tgcacaaatc ctacggcgac catgaggtgc tcaagggggt ctcgctcacc gcgaactcgg
    15121 gcgacgtgat cagcatcatc ggctcgtccg gctcgggcaa gagcacctgg ctgcgctgca
    15181 tcaacttcct cgaatgcccg accgccggcc gcatcctggt ggcgggcaag gaggtcgagc
    15241 tggtgcgcaa ccgcaagggc gagctcacgg taaaggacgc gcgccagctg cagcagatcc
    15301 gcacgcggct gtcgatggtg ttccagcact tcaacctgtg gagccacatg accgtgctcg
    15361 agaacgtcgt cgaggcgccg gtgcatgtgc tcgggctgtc gaaggcagag gcgcgcgagc
    15421 gtgcggagcg ctacctcgaa cgcgtggggg tgtggaagtt gcgtgacgcc tacccggccc
    15481 acatgtcggg cggacagcaa cagcgcgtcg cgatcgcgcg cgcgctggcg atggagccgg
    15541 cggtgctgct gttcgacgag ccgacctcgg cgctcgatcc ggagctggtc ggcgaggtgt
    15601 tgaaggtgat gcgctcgctc gccgaggagg ggcgcacgat gatggtggtg acgcacgaga
    15661 tgggcttcgc gcgcgaggtg tcgaaccacg tgatcttcgt gcaccagggg cgcgtcgagg
    15721 aggagggcga cccgaaggtg gtgctggtgc gtccgcgcag cgaacgcctg cagcagttcc
    15781 tgtccggcaa cctgaagtga ccggcgccgg gacgcccggc tgtgttcagc ggtagttgcg
    15841 gtgcatgcgc atcagcgtgc tcttgccgaa caggctctcc accaggtcga ccgcgagctc
    15901 ggcggtcatg ttgcagtgat cgagcgccgg gttgagctcg acgatgtcga gcgaggcgag
    15961 ctggccagtg tcggcgatca tctccatgca cagctcggcc tcgcggtagg tcggcccgcc
    16021 gcgcacggtg gtgccgacgc cgggcgcgat cgtcgggtcg aggaagtcca cgtccaggct
    16081 gacgtgcagg tgggtgttcg cgtccacgcc ggcgagcgcc tgctccatgg tcgcgcgcat
    16141 gccgatctcg tcgatgtagc gcatgtcgaa gacctcgacg cgcagctcgt gcaggaagcg
    16201 cttctcgccc tcatccacgc tgcgaatgcc gatctggcgg atctgcgcag gcgccaccgc
    16261 cgggatgtgg ccgccgatgc cggtgagcag ctcggggccg tggccgcaca ggcaagccac
    16321 gggcatgccg tggatgttgc ccgagggcgt catcgtggcc gtattgaggt cggcgtgggc
    16381 gtcgaaccac agcacgcgca gcttgcgacc ggtctcgcgg cagcgccgtg ccaccgcgct
    16441 gatcgagccg atggcgaggc agtgatcgcc gccaagcatg atcggcacgc gaccctcggc
    16501 cagttcggcg tataccgcct catgcaccgc gccgttccat gccgcgacct cgtcgagatg
    16561 gcggaagcca tccaccgccg gcagttccgg gttcgacggg ccggcgaggt tgccgcaatc
    16621 gcgcacttcg gcgccgaagg cggcgatcgc tcgccccagt ccggcgaccc gcaaggcctc
    16681 gggccccatg ctcgctccac gcacgcctgc acccacgtcg gtgggcaccc cgatcagact
    16741 gactttgaga ttttccatgg cggcgaattt acctcaggtc ccgccgtgat ggcaggggtg
    16801 gccttgcgat gtggtcggga ttgacggggt ggccccggag cgtgtattca ttgcgccttt
    16861 tttggcggcg gggatcatcg cccgcgtgcg ccggggcgcc gggatcccgg cgcgagagcg
    16921 ggcagcgccg gccccctgga gtattcgtgt cttcggtttc acttgctttt tcccccttct
    16981 cctttttcaa gccggcggca gcccgggggg cgcgatgagg cgcgcgcagg cgaacggcct
    17041 gctgctcgtc gcggcgctga tctggggcac cgccttcgtg gcccagcaga ccggcatgcg
    17101 cgacgtcggc cccttcacct tcaccggctc gcgcttcctc ttcggcgccg tgatgatcgc
    17161 gccgctcgcc ttcatggagc tgcgccggct cggccgccgc ggcacattcc tggacgtgcg
    17221 cgacctgctc gcatgcgcgt tgctcggcgc ggtgctgttc ctcggtgccg cgctgcagca
    17281 gatcggcatc atgagcacca ccgtgagcaa tgccggcttc ctcaccgcgc tctacgtccc
    17341 gcttgtgccg atcgcggggg cgctgctgct gcgcgagcgc tcgcactggt cggtgtggcc
    17401 tgcgagcctg ggctgcctgg gcggcactta cctcctcggc ggcggcagcc tgtcggcgct
    17461 cacggtgggc gacctgtggg tgatcgcgag cgcactgttc tgggccgccc acgtcatgct
    17521 ggtcgggcgc gtggccgcgc gcaagggcgc ctcggtgacg gtggcgatgc tgcagttcct
    17581 cgtggtcggc gtgctcggca tggcggtcgg cctcggcacg gaggaggtgt cgacggtggc
    17641 gctcgagcgt gcgctgccgt cgatcgccta cgccggcatc ctgtcggtgg gcgtgggctt
    17701 cacgctgcag gtggtggcgc agcgtcacac ccctgcggcc gacgctgcca tcctgctgag
    17761 ctgcgagacc ttgttcgccg ccctcgccgg gcgcctggtg ctgggcgaga cgctcaccgt
    17821 cgcgcagatg tccggcggcc tgctgatctt cgcctgcgtg ctggcggtgc agatcctgcc
    17881 cttgtggcgg gcgcggcgcg cggtggcggt ggaggccggc tgaggcgggt ctctcagtcc
    17941 gccgcaccgc cggccggcgc cggcagtcga cgcagccaca gcgcgcatgc gccggtgagt
    18001 agcacgcaca gccccaccag cgcggccacg ccctcccatc gccagtcggt ccaggcggtg
    18061 ccggcgaggc tgccgagcac gctggcgccc aggtagtagc tcgacaggta gagtgccgag
    18121 gcgagcgcgc ggcgttcgcc ggcgcgccgt cccacccagc cgctggcgag cgcgtgtgcg
    18181 gcgaagaaac cgaaggtgaa cacgccgacc ccggcgatca ccagccacag cggctgtgcc
    18241 agcgtgagca ggagcccggc gcccatgacc gcgaccatcg gccacagtac cttgcgccgg
    18301 ccgcggcgct cggcgaggcg gccgctcgcc gcggaggccc aggtgccgac gaggtagagc
    18361 aggaagatcg ccccgatcgc gctctggccc agcccgtagg gcgcttcgag caggcggaag
    18421 ccgaggaagt tgtacaggcc gacgaagccg cccatggcga ggaaggcgac caggaacagt
    18481 gccggcaggc cggggtcgcg gtagatcgcc agggtgtcgg cgaagatgcg cgccggtgtg
    18541 gcggcgcgcg cgcgaaagtt gcgcgaggcc ggaaggcgtt gccagaacac cagcgccgag
    18601 atcacgccga gcacgccgat caccccgagc gcgacccgcc acgagctcca gtccgtgagc
    18661 agcgcggcga cgaagcgccc gctcatgccg ccgagcgcgt tgccggcgat gtacagcccc
    18721 atcgcgcgcg cctgcgcgcc cggggcgatc tcctcgccga tgtaggccat cgcggcggcg
    18781 gggagcccgg cgatcacccc gccgaggagc gcacgcaaga ccagcagcgc gccgaagtcg
    18841 ggcgcgaagg cggtggcgag cgcgagcagg gcggcgatcg cgagcgccgc cttcatgacc
    18901 tgctggcggc cgaggcggtc ggcaagcacg ctgcccggga tcagcatcag cgcgagcccc
    18961 gcggtggtgg cggacaccgt caggctggcg ctcgccgcgc cgacgtcgaa ctcggcggcg
    19021 agcagcggca gcaggggctg ggtgctgtag accatcgcga aggtcgcgaa gccgccgacg
    19081 aacatcgcca ggttggcgcg ccggtagccg ggcgtgccgg cctcgagctg ggtcggcact
    19141 ggcgggggtc tttcggcggg aagggcgggc atgaggtgat gacggtgagc gagggggcga
    19201 atcgggagcg atcttaggat ggcatcagat ctatcgtcca atatattctg agcgcttcat
    19261 ccatatatgg aagcgaatga tggagctgcg tcacctgcgc tatttcgtcg ccgtcgccga
    19321 ggagctcaac ttcacccgcg ccgcggcgcg actgcgcatc ggccagccgc ccctgtccat
    19381 gcagatccgc gatctggagg aggaggtcgg cgcgcgcctg ttcgagcgcg gtccgcgccg
    19441 ggtggcgctg agcgccgcgg gggagcgctt cctgccgcac gcgcgccgca tcctcgatgg
    19501 ggtggaggag gccgttgccg aggcccggcg cgccgcgcgc ggcgagctgg gcgagctgcg
    19561 cgtcggcttc acctcctcgc tgcccttcac cgatctgctg cccgacgcgc tcaatgccta
    19621 tcggcggcgc tttccggcgg tgcggctgca gttgcgcgag ctgttcaccc cggagcagtt
    19681 cgcggcgctc gcgcgcggcg aactcgatgt cggcttcgtg cgcctgcagg caggcgcacc
    19741 gcccgcgggc atcgtgctgc gcgaggtggc gcgcaacccg ctgcgcctgg tcgtgaatgc
    19801 cgcgcaccgg ctggcggacg cggagcgggt gagcatcgcc gaactggccg gggaggattt
    19861 cgtcggcttt ccggccgatg tcggcaccga tctgccgggt gtgttgcgca acctttgcag
    19921 gcaggcgggc ttcgagccgc gcgtcgtgca gaccgcgcgc gaggccacca cgcagatcgg
    19981 cctggtcgcc gccggcctcg gcgtggcgct gctgccggcg ccgctcgagt cggtgcggat
    20041 cgcgcgcgtg cgctacctgg cgctggccga gccggaggcg cagttccgcc tcgcgctggc
    20101 cgtccgcgag ggcgagccgt cgccgctgct cgccggcttc ctggaggtgc tggagcgcct
    20161 gcgtgcgggg caggccagcg tcacctgagc gtgcccgggg ggcagcgtct gtgctcgcgc
    20221 atcaatggcc cgcgccggcg aagaagcgct gccgcgtctc tcccggcagc tccatgcccg
    20281 tgttgcgggc gcgctgcagc agctcccagt agtagcggta ggaggcgcga tcgtgcagac
    20341 gtccctggtg acggatcggg ccccaggcgt tgtcctgcgc tgcgcacagg atcgccgcgg
    20401 cctcctcgac ctcggagaag tcgggctgca tcgcggcgat gatcggcagg atctggttgg
    20461 ggtggatgct ccacatgcgc aggtagccga actcgcgccg ggcacgctcg gcatcgtggc
    20521 ggatcaccgc gacgtcctgc agctcggtgg tgacgttgtg cgaggggatg acgccgttgg
    20581 cgagcgcggc ggcggcgatg tcggccttgg cgcggaccac cagcgggtgc tcgaactggc
    20641 cggggctctt catggcgctg ccggggatgg cgccgtggtg gccggacacg aagtccatga
    20701 ggccgaagtc gatcgactcg acgccgtcga gcgcggcgat ctcccaggcc tcgcgcaggg
    20761 cgccgtgggt ctcgaccagc acatggatgg gcagcgcgcg ctcgaggccg caggcggcct
    20821 cgacgcggcg cagttcgcgg atctgctcgg cggcatccgc cgcggaacgc accttgggaa
    20881 tggtcacgaa ggcgagccgc cggccggcac caccgaccag gatctcgagg tcgcgctgcc
    20941 agtgcgggtg ggtgatgtcg tggatgcgcg cgccgacgcg tccgaagtgg ttctccgcgc
    21001 cattgaccac ctcgaccacc atgcgcgcgt gctcggcttc ggcgccggcc tgggcgccgt
    21061 cctcgcagtc gcaggtgagg tcgaacaccg ggccgagctc ctgctgcagc ttgagcgcct
    21121 tcatcatgag cttctcggcg ccggcgtagt ggtccacggc gggcagggag gggaagggct
    21181 tttcgccggc gaacaggacc tgagcggggt gaagcgacat ggcggtctcc tcggatgggc
    21241 tgcggctggc atgcgggccg cggcgaggcg gtgcggcggg cgccgcggaa atgaaaaaag
    21301 gccacggatt ctaccccgtg gcctttcgcg agggcggcac gtggccgccc cggatcgcga
    21361 cttacttgag catgtcggcc acggccgcgc gctcgtcctc gagttccttg agggtgatgg
    21421 cgatcttgcc cttcgagtac tcgtcgatct ccaggccctg gatgatcttg aactggccgt
    21481 ccttgcactc gcaggggaag ccgaacacca cgccctcggg gatgccgtag gagccgtcgg
    21541 acggaacgcc catggtgacc cagtcgctcg agccgagcac ccagtcgtgc acatggtcga
    21601 tggcggcgtt ggcggccgag gcggccgacg acaggccgcg ggcctcgatg atggcggcgc
    21661 cgcgcttgcc gacggtgggc aggaagacgt cgttgttcca ggcgtggtcg ttgatcagcg
    21721 ccttgacgct gtcgccgttc gactcgcaga agcggtagtc ggcgtacatc gagggcgagt
    21781 ggttgcccca cacgaccatc ttcttcagcg acgacacttc acggccggac ttggcggcga
    21841 gctgcgacag cgcgcggttg tggtccaggc gcagcatgcc gtggtagttg ttcgggttgg
    21901 tgcggccgac cttgatggcg gcggcgcggg cgatgtaggc gttggtgttg caggggttgc
    21961 ccacgaccag cacgcggacg tcttccttgg cgttctcggc gatggccttg ccctgaacgg
    22021 tgaagatcgc gccgttggcg gtcagcaggt cggcacgctc catgccgggg ccgcgcggac
    22081 gggcgccgac cagcaggcac acgtcggcgt ccttgaacgc gacgttgggg tcgtcggtgg
    22141 cgatcatgcc ggcgagcagc gggaaggcgc agtcttccag ctccatcatc acgcccttga
    22201 cggccttctg ggcctggggc aggtcgagca gctgcaggat gacgggctgg tccttgccca
    22261 gcatttcgcc actggcgatg cggaacagca ggctgtagcc gatctggccg gcggcgccgg
    22321 tgacagcgac gcgcatgggg gctttgctca tgtgattact ccctcgagtg agacggtcgt
    22381 atgaaggtgc tggaaacctg cccgggttcg tcgcgacgta ccgtgcgccg ccgcatggcg
    22441 gcgtcttccg gtcgggcctg cgcggcacgg ccacgcgtgc gcgggtaccc tttctgggcg
    22501 ccggcatact agccccatgc agatagcctg tcaaatgcca tcttatgtct tatataagat
    22561 acaagactaa agatagacgt ttatgaaaat ttatgctcaa atgcgcgcat gtcgcaggag
    22621 tcgcctacct tcagcccgct ctaccgtcag atcaaggcct tgatccttca ggcgcttgag
    22681 gctggggaat ggcgccccgg ccaggccatt ccgagcgagc aggaactcgc cgcgcgcttc
    22741 agcgtttcgc agggcaccgt gcgcaaggcc atcgacgaaa tggcggccga caacctgctg
    22801 gtgcgcaagc agggcaaggg cactttcgtt gcctcgcaca acgacccgcg cgcgctcttc
    22861 cgctttctcc gcctcgtgcc ggtcgacggc gatctttctc ctccacaaag cataccgctg
    22921 gattgctggc gtgcgaaagc cggtcaggag gcgtcgcgca tgctcgcgat cgagcccggt
    22981 gcgccgatca tcatcgtccg tcgtctgctg aagttcgccg cccggcccgt cgtcatcgac
    23041 gagatctacc tgcccggcga ggtctttcag ggtctcagcg ccgagaccct gcagggctgg
    23101 aacgggtcgc tctacagcct cttcgaaacc cgcttcggcg ttcgcatgat ccgcgcgcag
    23161 gagcgcatcc gcgcggtcgc cgccgatcgt ggcgccgccg aggcgctcaa tgtccaggaa
    23221 gggacgccgc tcctgtcggt cgagcgtgtc acctacacct atggcgacaa gccggtggag
    23281 tggcgtcgtg gcctgtattc gaccgcggag catttttatc tgaacgagct gaattgatct
    23341 gtcgcgcatg ggctgcaggg caggaccggc gctataattt tttgtcgttt ttcggagtcc
    23401 gcgacggggg tcgtcgcaca tgcagagggg agtcttcatg tcagaagtaa cagcgcgcaa
    23461 accaaggccg aagtacctgg ccctgaacga gatccggctg cctttgccgg ggatcgtctc
    23521 gatccttcac cgcgtcagcg gcgtgggctt gttcctgatg ttgccgttcc tgttgtacct
    23581 gctcgatcgc agcctcggct cgccggagac cttcgagacc ttcgccgcgg tggtcgacaa
    23641 ctggttcatc aagctgatcc tgttcggcct gctgtgggcc tacctgcacc acttctgtgc
    23701 cggcatccgc ttcctgctgc tcgacctgca caagggtctg gagctcgagg aagcgcgcaa
    23761 gtcctccaaa atcgttctgg tcgtgagcct cacgctcacc gtgatcatcg gggtggtcct
    23821 atggtgaaac agcgtatcgt cgtcggcgcg cactacggtc tgaaagactg gatcgcgcag
    23881 cgtgccaccg ccgtctacat ggcggcctat accatcatct tcgcgctgtc ggcgttcagc
    23941 ctgcgcgagc tgaactacca ggagtggtcc ggcctgttct cgcacggcct gttcaagttc
    24001 ctgagcttcc tgttcttcct gtcggtcttc tatcacgcct ggatcggcat ccgcgacctc
    24061 tggatggact acatcaagcc caacggtgtg cgcctcgcgc tgcacctggt caccattttc
    24121 gtgctcgtcg gctacgccgg ctgggcagcc cagatcctgt ggaggcttta agcgtgaacg
    24181 tcgcgaagcg tacctttgat gcggtcatcg tgggcgccgg cggtgccggc ctgcgtgcgg
    24241 ccctgcaact ctccgaagcc ggcctcaaga ccgccgtgct gaccaaggtg ttcccgaccc
    24301 gttcgcacac cgtggcggcg cagggcggtg tcgccgcctc gctcggcaac tcgaccgagg
    24361 acaactggca ctggcacatg tacgacaccg tgaaggggtc ggactggctg ggcgaccagg
    24421 atgccatcga gttcatgtgc aagaaggcca acgaggtcgt catcgagctc gagcactacg
    24481 gcatgccctt cgatcgcacc gacaacggca agatctacca gcgcccgttc ggcggccact
    24541 cgatgaacta cgggcaggcg ccggtgatgc gctcctgtgc cgcggccgac cgtaccggtc
    24601 acgccatgct gcacgcgctc taccagcgca acgtgcgtgc gaacacccag ttcttcgtcg
    24661 agtggatggc gctcgatctg atccgcgacg ctgacggcga tgtgctcggc gtgaccgcga
    24721 tggaaatgga gaccggtgag gtctcgatct tccatgccaa ggccaccatc ttcgccaccg
    24781 gcggtgccgg tcgcatctac tattcctcga ccaacgcctt catcaacacc ggtgacggcg
    24841 tgggcatggc ggcgcgcgcc ggcatcccgc tcgaagacat ggagttctgg cagttccacc
    24901 ccaccggcgt ggccggcgcg ggcgtgctga ttaccgaagg cgtgcgcggc gaaggcggca
    24961 tcctgcgcaa cgcccagggt gagcgcttca tggagcgcta cgcgcccaac ctcaaggacc
    25021 tcgcctcgcg cgacgtggtc tcgcgcgcga tgaccaccga gatcaacgaa ggccgtggtt
    25081 gcggtccgga caaggatcac gtgctgctcg acatcacgca ccttgcgccc gacaccatca
    25141 tgaagcgcct gcctggcatc cgcgagatcg cgatccagtt cgccggcgtc gatccgatca
    25201 aggcgccgat cccggtcgtg ccgacctgcc actaccagat gggcggcatc ccgaccaact
    25261 acaagggcca ggtcgtcgtt cccaaggacg gcaacccgaa cagcccggtc gcaggcttct
    25321 acgctgcggg cgagtgcgcc tgcgcctcgg tccacggcgc caaccgcctc ggcaccaact
    25381 cgctgctcga cctgctggtg ttcggcaagt cggcgggcga gaccgtggtc gaggacttcc
    25441 agtccggcca gctcaagctg aagccgctgc ccgccgatgc cgccgacgtc tcgctggccc
    25501 gcctggcccg tctcgacggc cagaccaacg gcgagagcgt gttcgacgtc ggcctggaga
    25561 tgcgccgcac gatgcagaag cacgccggcg tgttccgctt cgacaacctg ctcaaggaag
    25621 gcgtgcagaa gatcggcgag gtcgccgagc gtgccaagcg caccgagatc aaggacaagt
    25681 ccaaggtctg gaacgtcgcc cgcatggaag ccctcgagct cgacaacctg atcgaggtcg
    25741 cgcgcgccac catggtctcg gccgaggccc gcaaggagtc gcgtggcgcc cacgtccgcg
    25801 acgacgcgcc ggataccgcc gagaacccca acggccgcga cgatgccaac tggctcaagc
    25861 acaccctctg gtactccgaa ggcgaccgcc tcgattacaa gccggtgaac ctgaagccgc
    25921 tgtccgacga cgtcgagccg atcgcgctcg ccaagcgcac ctattgagcg cccgggagaa
    25981 acattcatga ccaagcgtac cgttcaattc aagatctacc gctacgatcc ggacaaggac
    26041 gagaagccct acatgcagga catctcggtc gagctcgagc cctccgacaa gaagctgctc
    26101 gatgcgctcg tccgcctgcg tgccaaggac gactcgatgt ccttccgccg ctcctgccgc
    26161 gaaggcgtgt gcgggtcgga tgcgatgaac atcaacggca agaacggcct ggcctgcctg
    26221 accgacgtcg acagcctgca gcagccgatc acgctgcgcc cgctgcccgg cctgccggtg
    26281 atccgcgacc tgatcgtgga catgacgcag ttcttcaagc agtaccactc gatcaagccc
    26341 tacctggtga acaacgaccc gccccccgag cgcgagcgtc tgcagtcgcc ggaggatcgc
    26401 gaggagctca acggcctcta cgagtgcatc ctgtgcgcgt gctgctcgac gtcctgcccg
    26461 tcgttctggt ggaaccccga caagttcgtc gggcctgccg gcctgctcgc ggcctaccgt
    26521 ttcctcgccg acacccgcga ccaggacacc ggtgcgcgcc tcgacaacct cgaggacccg
    26581 tatcgcctgt tccgttgcca caccatcatg aactgcgtcg atgtctgtcc gaagggtctg
    26641 aacccgaccc gcgcgatcgg caagatcaag gacatgatgg tccgccgcgc gatctaaggg
    26701 cgggcacagt cgatgacgat caacaggggg cgcgtgcgct ggcagtgtcg tcgggctctg
    26761 ctcgagctcg acctggtgtt cacgcgcttt ctagagcggc atttcgatcg tctcaccgac
    26821 gatcagctgg cggatctgga cgacttgctg cgctgcgacg actacgacat ctgggcgtgg
    26881 gtcaacggca gcaaggcatg tgagaacgac cgctggaagg agatgatcgg actgctgcgt
    26941 caggggtgac gcggcagtac cggtccgata aaagaccaaa ggcagttaaa ccggcaagta
    27001 gaagggacga tctatgagca ctgaacgcac tgcaacgctt accgtcgatg gcaagaccgt
    27061 cgaattcccg gtcatgaccg gcacccacgg ccaggacgtc atcgacatcc gcaccctggg
    27121 cggcaagacc ggcctcttca cctacgactc cggcttcctg tcgaccgcca gctgcaagtc
    27181 gaagatcacc ttcatcgacg gtgacaaggg cgagctgctg taccgtggct atccgatcga
    27241 gcaactcgcc gagcaatgca acttcctcga ggtcgcgtat ctgctcaaga acggcgagct
    27301 tcccaacgcg gagcagaaga ccgcgttcga gagcacgatc aagaaccaca cgatgctgca
    27361 cgaccagatg acgaagttct attcgggctt ccgtcgcgat gcgcacccga tggcggtcat
    27421 ggtcggtgtg gtcggcgcgc tttcggcctt ctaccacgag gcgatggact tctccgacgc
    27481 gcagcaccgc agcgtgtcga tcaaccgcct gatcgccaag ctgccgacca tcgttgcgat
    27541 ggcgtacaag tacaacaagg gcgagccctt catgtacccg cgcaacgacc tcgactacac
    27601 cgcgaacttc atgcacatga tgttcggcac cccgtgcgag aagtacgagc cgaatcccgt
    27661 tctggtgcgc gcgctcgacg tcatcttcac gctgcacgcc gatcacgagc agaacgcctc
    27721 gacctcgacc gtccgcctgg ccggctcctc gggcgcgaac cccttcgcct gcatctcggc
    27781 cggcatcgcc tgcctgtggg gcccggcgca cggtggcgcg aacgaagcct gcctgaacat
    27841 gctcgaggaa atcggtgacg tgtcccgcgt gagcgaatac atcgcgcgcg ccaaggacaa
    27901 gaacgacagc ttcaagctga tgggcttcgg tcatcgcgtc tacaagaact tcgatccgcg
    27961 tgccaagctg atgcagaagg tctgcaacga agtgctgacc gaactcggcc tggagaacga
    28021 ccgcctcttc aagctggcga tggagctcga gaagatcgcg ctggaagacc cgtacttcgt
    28081 cgagaagaag ctctacccga acgtcgactt ctactcgggc atcgtgcaga aggcgctcgg
    28141 cattccgacc tcgatgttca cctgcatctt cgcgctcgcc cgtacggtgg gctggatcac
    28201 gcagtgggaa gagatgatca ccgatcccga gtacaagatc ggccgtccgc gtcagctcta
    28261 cgtcggtacc gcgcgccgcg atgtgccggc gctcgcgcag cgtccgtaag agacgatgaa
    28321 gaggggctgc aggatccgcc gcgactgacg gtgacggggt ggttgcgcgt gcgcggccat
    28381 cccgtttttc catcggaacc catgcgtcgg ccgcactccc gcacccgaaa acagggcaac
    28441 agaacaccac aggtgcttat cccatgatga agcaactcga acagacttcg cacttgttcg
    28501 gctcgaacgc gccgttcatc gaagaacagt acgaaaacta cctcgccgac ccgacctcgg
    28561 tctccgccga gtggcgcgac tatttcgaca agctgcaggc gcaggtcggc gccgccgcgc
    28621 gcgacgtgcc gcacggcccg gtcatcgccg ccttcgagca gatggccaag cgcggcccgg
    28681 tgcgcaccgt cgtcaccgct ggcgaggaca agcagcaggt ctccgtgctg cagctgatca
    28741 acgcctatcg cttcctcggc aaccgctggg ccaacctcga cccgctcaag cgcaccgagc
    28801 gcccgcagat cgccgaactc gagccgtcct actacggctt caccgaggcc gatctctcca
    28861 agagcttcaa cgtcggctcc ttccacggct tcagcaccga gcgcgccacc ctgcgcgaga
    28921 tcctcgaggc gctgcgccag acctactgcg gcccgatcgg cgccgagtac atgtacatga
    28981 ccgacatcgg tcagaagcgc tggatccaga gccgcctcga gagcctgcgc ggcacgccga
    29041 agttctcggc cgagatgaag aagcgcatcc tcgagcgcac caccgccgcc gagaccctcg
    29101 agcgctacct gcatacccgc tacgtcggcc agaagcgctt ctcgctcgaa ggcggcgagt
    29161 cggccatcgt cgcgatggac gagctgatcc gcgtcgccgg cagtctgggc gtgcaggaaa
    29221 gcgtgatcgg catggcccac cgcggccgtc tcaacgtgct cgtcaacacc ctgggcaagt
    29281 cgccctcgat gctgttctcg gagttcgagg gcaaggccgc cgccgacctc accgccggcg
    29341 acgtgaagta ccacatgggc ttctcgagcg acgtgatgac cccgggcggc ccgatgcacc
    29401 tgacgctcgc gttcaacccc tcgcacctcg agatcatcaa cccggtggtc gagggttcgg
    29461 tgtatgcccg ccaggtccgt cgcggcgacg ccgacaagaa ccaggtgctg ccggtgctga
    29521 tccacggcga cgccgccgtg gccggccagg gcgtcaacca ggaaatgctc aacttctcgc
    29581 agacccgcgg ctacggcacg ggcggcacgg tgcacctggt cgtcaacaac cagatcggct
    29641 tcaccacctc cgacccgcgc gactaccgct cgtcgctgta ctgcaccgac atcttcaaga
    29701 tggtcgaggc gccgatcttc cacgtcaatg gcgacgaccc cgaggccgtg gccctggtca
    29761 ccgcgctggc ggtcgagttc cgccaggagt tcaagaagga cgtggtggtc gacatcatct
    29821 gcttccgcaa gctcggccac aacgagcagg acgagccgat ggtgacccag ccgctgatgt
    29881 accgcaccat ccagaagcac cccggcaccc gcaagctcta cgccgaccgc ctggtcgccg
    29941 agggcacgct gaagtccgac gagcccgacc agatgatcgc cgagtaccgc gagcacctcg
    30001 acaagggcca gctgctgtac aacccggtgc tctcgggcca caaccgccag ttcgccgccg
    30061 actggacgcc gtacatcaag caaccctaca ccgacgagtg cgacaccacc gtgccggtgc
    30121 aggagatcaa gcgcctgtcc gagcgcctga gcacgatccc ggcgaacttc acgctgcact
    30181 cgcgcgtcaa gaagatcatc gacgaccgcg cggccatggg ccggggcgaa gtgcccttcg
    30241 actggggcat gggcgagaac ctcgcctacg ccagcctgct cgcgcagggc tacggcgtgc
    30301 gcctctccgg cgaagacgtc ggccgcggca ccttcttcca ccgccacgcc gtgctgcacg
    30361 accagaagcg cgagcgctgg gacgagggca tctacaagcc gctcgaccac atccaggacg
    30421 gccaggcacg cttccagagc tacgactcgg tgctgtcgga ggagggcgtg ctcgccttcg
    30481 aatacggcta cgcgaccacc gaacccaacg agctggtgat ctgggaagcc cagttcggcg
    30541 acttcgtgaa cggtgcccag gtggtgctcg accagttcat cagctcgggc gaggccaagt
    30601 ggggccgtct gtgcgggctc acgctgatgc tgccgcacgg ctacgagggc cagggccccg
    30661 agcactcgtc tgcccgtctc gagcgctaca tgaacaacgc cgccgagcag aactggcaga
    30721 tctgcgtgcc gaccacgccg gcgcaggtgt tccacctgct gcgccgtcag gcgatccgca
    30781 aggtgcgcaa gccgctgatc atcatcacgc cgaagtcgct gctgcgtcac aaggaggcga
    30841 tctcctcgat cgaggagctg gccaacggca gcttccagac cgtcatcccc gaggtcgaga
    30901 agctcgacgc caagaaggtc aagcgcgtgg tgctgtgcca gggcaagatc tactacgagc
    30961 tcctcgcgca tcgtcgcgag aacaagatca ccgataccgc gctggtccgc atcgagcagc
    31021 tctatccctt cccgaccgag gccttcgcca aggcgatcga gcagttcccg aacgccaagg
    31081 agatcgtctg ggcgcaggaa gagccgcgca accagggtgc ctggtactgg ctcgcctcgc
    31141 gccagcacct ggtcaacgtg ctcggcacca agcgccgcct gctgctggtg agccgcccgg
    31201 ccgccgcttc gcccgcggtc ggctactacg ccaagcacaa cgcccaacaa aaggcggtcc
    31261 tcgaaaacgc cttcggtccg atccaggaca ccacgccgca gttcccgcac tgaaaaacat
    31321 ctagggagag aaattcatgc tgatcgaagt caaagttccg cagctgtccg agtcggtttc
    31381 cgaagccacg ctggtcacct ggcacaagaa ggaaggcgat gccgtcgcgc gcgacgagaa
    31441 cctgatcgac atcgagaccg acaaggtcgt gctcgaaacc ccggccccgg ccgacggcgt
    31501 gctggtcaag atcatcaagc agggcggcga caccgtaacc tcgggtgagc tgatcgccca
    31561 gatcgacacc gaagccaagg ccgccgccgg tgcggcagcg gcggctccgg ctgccgcccc
    31621 ggccgccgcg cccgccgcgg ctccggctgc gtccggtgcc gccggcgccg ccagcccggc
    31681 cgcgcgcaag atcctcgacg agaagggcat cgccgccggc gacgtcgcag gctccggccg
    31741 tggcggtcgc gtgaccaagg aagatgccgt cgccgcccag cccaaggctg ccgccgctgc
    31801 ggcgccggcc gcggtgcaac tgaccggcga ccgtccggaa gagcgcgtgc cgatgacccg
    31861 cctgcgcgcc cgcatcgccg agcgcctgat ccagtcgaag aacgagaacg ccatcctgac
    31921 cacgttcaac gaggtcaaca tggcgccggt catggccctg cgcaagcagt acggtgacaa
    31981 gttcgagaag gcgcatggcg tacgcctcgg cttcatgggc ttcttcgtca aggccgccgt
    32041 ggccgcgctg aagaagttcc cgatcctgaa cgcctcggtc gatggcaacg acatcgtcta
    32101 ccacggctac atcgacatcg gcatcgcggt cggttcgccg cgcggcctgg tggtgccgat
    32161 cctgcgcaac gccgaggcca tgtcgatcgc cgagatcgaa ctcaagatcg ccgagttcgg
    32221 ccagaaggcc aaggatggca agctctcgct cgacgacctg tcgggcggca ccttctcgat
    32281 ctccaacggt ggtgtgttcg gctcgatgat gtcgaccccg atcatcaacc cgccgcagtc
    32341 ggccatcctc ggcatccacg ccaccaagga ccgcccggtg gtcgagaacg gccagatcgt
    32401 gatccgtccg atcaactacc tggccatgtc ctacgaccac cgcatcatcg acggtcgcga
    32461 ggcggtgctc ggcctggtga cgatgaagga agcgctggag gatccggccc gcctgatcct
    32521 ggatgtgtga gcggacgtaa ggggcgaggc gcgaggcgta aggagcggtg gccgctccat
    32581 gcctcgcggt tcgccttgcc tgggcgccgc agggcgcctg ttcgcacctg actcctgact
    32641 cctaactcct cacaggtaac cccatgtcca aagaattcga cgtcctcgtc atcggcggcg
    32701 gccccggcgg ctatgtcgcc gcgatccgcg ccgcgcagct cggcttcaag accgcgtgct
    32761 gcgaatcgaa tccctatgcc gatcccaagg gcgagccgcg tctcggcggc acctgcctga
    32821 acgtcggctg catcccctcc aaggcgctgc tgcacacctc gcacctgttc gaggaagccg
    32881 gccacgcctt cgaaggtcag ggcatcagcg tcggcacgcc caagatcgac gtgcccaaga
    32941 tgatcgcccg caagtcgggc atcgtcgacc agctcaccgg cggcatcaag ggcctgttca
    33001 agaagaacaa ggtcaccctg ctcaatggcc acggtgcctt catgggcaag gccgaggccg
    33061 gctggcaggt ccaggtcggt gaagagctcg tcgtcgccaa gcaggtcatc gtcgccaccg
    33121 gctcggcccc gcgccacctg ccgggcgtac cggtcgacaa caagatcgtc tgcgacaacg
    33181 tcggcgcgct cgacctcgac gcggtgccga agaagctcgc cgtcatcggc gccggcgtca
    33241 tcggcctcga gatgggctcg gtgtggcgcc gcctcggtgc cgaggtgacc gtgctcgagg
    33301 ccatgcccga gtttctgtcg ctcgccgacc aggacgtggc caaggaagcg ctcaaggtct
    33361 tcaccaagca gggcctcaag ttcaacctcg gcgtcaccat cggcgaggtc aaggtgggca
    33421 agaagggcgt cagcatcgcc tacaaggaca aggacggcgc cgaccagaag ctcgaggccg
    33481 accgcctgat cgtgtccgtc gggcgcgtgc ccaacaccca gggcctcaac gccgaggccg
    33541 tcggcctcaa gctcaacgag cgcggccaga tcgaggtcga cgaccactgc aagaccaacc
    33601 tccctggcgt gtgggcggtg ggcgacgtgg tgcgcggccc gatgcttgcg cacaaggcga
    33661 tggaagaggc ggtcatggtc gccgagctga tggcgggcca ggccgggcac tgcaacttcg
    33721 acaccgtgcc ctgggtgctg tacaccagcc ccgagattgc ctgggtcggc aagaccgagc
    33781 agcagctcaa ggccgccggg gtggcctaca aggtcggcaa gatcccgttc ctggccaatg
    33841 gccgcgcgct cggcatgggc gactcgaccg gcttcgtcaa gatgctcgcc gacgccgcca
    33901 ccgaccgcat cctcggcgtg cacatcatcg gcgccaacgc gtcggagctg atctccgagg
    33961 ccgtggtggc gatggagttc gccggctgct cggaagacct ggcgcgcatc tgccacgccc
    34021 acccgaccct gtcggaggtg gtgcacgagg ccgcgctcgc ctgcgacaag cgtccgctgc
    34081 acttctgagc gaggcgtgag atgtgagggg tgaggtgcgg gggcttccct gcgcccaccc
    34141 cttttcgcgt caacctgcag ctctccgatc aacgctcctg accgattctc catgccccat
    34201 cgcatcctga acgttcccca gcacgggatg atcgacgcct acgaagccct gctgaagacg
    34261 cgcggctacc agtccgatcc cgcccagcgc gccgcggcgc agcgcctgca gggcctctat
    34321 accgagctcg tcggcttcaa ggctgcacgc cagggcagtc ggatcaagca gttcctcaac
    34381 aagcccaaga tgccgcgcag tgtgtatttc tggggcgggg tggggcgcgg caagagcttc
    34441 ctgatggact gcttctacga ctcggtgccg tatcgccgca agcgccgggt gcacttccac
    34501 gccttcatgc aggaggtgca gaacgacctg cgcaagttca acaacgcgcc cgatccgctg
    34561 cagaaggtcg ccgaccgcat ctccgagcac acccggctgc tgtgcttcga cgagttccac
    34621 gtctccgaca tcgccgacgc gatgatcctc gggcgcctgc tcgacgcgct cttcgaccgc
    34681 ggcgtgatct tcgtgatgac ctcgaactac ccgccggacg ggctctatcc caacggcctg
    34741 atgcgcatca acttcctgcc cacgatcgag aagatcaagc agcgcttcga cgtcatcgag
    34801 gtcgaccacg gcaccgacta ccgcctgcgc acactcgaga agatggagat ctacctcgtg
    34861 ccgcacgacg acgcggccga gcgcaagatg gccgaggact tccgccgcct cgccgcgagc
    34921 gaggggcgcg gcggcagcgt cgagatcctc gggcgcaaca tcgacgtggt gcgccaggcg
    34981 cccggggtga tctggttcga cttcgccagc ctgtgcggcg gtccgcgctc gcagaacgac
    35041 tacctcgaga tcgcgcgcga gcaccacacg gtgatcctgt cgaacgtgcc caagatgctc
    35101 gtcggcaacg cttccgaggc gcgccgcttc acctggctga tcgacgtgct ctacgaccac
    35161 cgcgtcaagc tcatcatgag cgcggcggtg gaggcccatg acctctacac cgagggccat
    35221 aacgcccacg agttcgtgcg cacggtgagc cgcctgatcg agatgcgcac gcgcgactac
    35281 ctcgccgagc cgcatcgcac cgagtagccg gcctgtggcg cacagtccag gctcctggca
    35341 tgtcgtgata taattgttca aatgtaaatg accgccgcgg cttgtggcgg ctcaccgtcc
    35401 gcgccccgca tcccgccgga cggaaggctg caaaggcgtc ccggccgacg gtgatgcctt
    35461 ggcgccccgg caccctcttc ggctgccgcg accgacaatt cccgaccaca ggagccacgc
    35521 tgtgacgcac aagctcacgg ccttcctcgc gttcgtcttc gtgatcgcga tgctgggcct
    35581 cacccccgca ccgggccacg ccgccgagcc ggcgagcggg tccacctctg aacaggccgg
    35641 ccaccagcgc ctcgccgatc tcctcgagga cgaggccgcg cgcacggcgc tcgtcgagca
    35701 gctgcgcaag ctcggcgagg aggaggccgc gcgcgcggtc gagtccggtg cgccgaccca
    35761 gaccctcgcc ggccaggtcg ccggcctcac ccagaccgtc gcgcagggcg tggtgagcga
    35821 gagcgccgcc gccgtcgacg ccctcggcgt ggcctggaag caactcgccg cagccgatcc
    35881 gcagcccctg gcctgggccg cggccgagtt cgtgctgctg gtggcggtca cctggatcgt
    35941 cttccggctg ctgagcgcgg cggtcggcgg gatcttccgc gcactcgacc gctatgccgg
    36001 cgcccgcgat ggcccgcgtg cgctcggttg ggtgcggcgc agcctggcgc ttcttggcgc
    36061 tgccgtgctc gacctgctga tcatcggcct gtcctggctc gccggctatg gcgtggcgct
    36121 cttcgtcatc ggcgacacgg gcagcatgcg catccaggag tcgctctacc tcaacgcctt
    36181 cctgctggtg gagctgatcc gcgtcgcgct gcgagtgctg ctctccggcc gcggcgagaa
    36241 cctcggcatc ctgccgatcg ccgccgagga caaggcctat tggtcggcct gggcttcgcg
    36301 catggtcttc ttcgtcgcct acggtctcat gctggtcgtg ccggtcatcg accactacct
    36361 cacaccggcg ctcggccgcg cggtcttcat cgcgatcctg ctcggtgcgg tgctgcgcgc
    36421 cgcggtggtg gtgatgcaga accgccagcg tgcgagccag gcgctcgagg ggctggccga
    36481 ccgcatgcag acgcctttcg ggcgtatcgc gctcaccatc ggggcacgga tctggcacgt
    36541 ggtggcgctg gtctacctga tggcgatcct ggtcacctcc ctgctttatc ccgaacaggc
    36601 gctgcccttc atgatcgccg ccaccggaca gaccttgctc gcggtcgggc tcggcatcgc
    36661 gctcgcggcg ctgctcacgc aggtgatcct gcgccgcatc gagctcggcg acgagttgcg
    36721 cctgaagttt ccgctcctcg aggcgcgcct caacgcctac gtgcccagtg cgctcaagat
    36781 cgcgcgcttc gtcatcctcg cggtggtcgt ggccttcatc gtggacgcgt ggacgccatt
    36841 cgatctcggc gcctggatcg cctcggaggc gggagcacgt gtgcttggcc gcgcgctgtc
    36901 ggtcgccgtc atcgtcaccc tcgcgctgct ggcctggctg gtggtggcga gctggatcga
    36961 gttccgcctc aacccgcagg cgggcatggc gcccaacccg cgcgcgcgca ccctgctgac
    37021 catcttccgc aacgccatcg cgatcgcgct ggtggtggtc acgaccatgg tggtgctggc
    37081 cgagatcggc atcaacatcg cgccgctact ggcgggtgcc ggcgtactcg gcctggcgat
    37141 cggcttcggc gcgcagaagc tggtgcagga cgtcatcacc ggcgtcttca tccagctcga
    37201 gcgcgcgatc gacgtcggtg acctcgtcac tgccggcggc atcaccggca ccgtcgaacg
    37261 catgacgatc cgttcgctcg gcatgcgcga catgcacggc acctaccatc tgctgccgtt
    37321 ctcctcggtc gacacggtgt cgaactacaa ccgcgacttc gccttccacg tcggcgaata
    37381 cggcatcggc tatcgcgagg attccgacga ggccatcgtc cacctgcgtg cggccttcga
    37441 cgagttgctc gcggacgagg cccagcgcgc gcagatcctc gacccggtgc tggatgtcca
    37501 cggcgtcacc gcgctggccg acaactcggt aaatatccgc gtccgcatca agaccctgcc
    37561 gggtgggcag ttcggcgtcg gacgcgccta caaccgcttg gtcaagcgcc acttcgacgc
    37621 cgcaggcatc gagatcccgt acccgcagat gacgctccac tttggcgagg acaagcaggg
    37681 caaggcgccg ccggcgaggg tctgcatcga gggggagccc gtaccgctgc tcgctccggg
    37741 gcgttgactc cgcccgcgtc cacgtaaaac ggcccgcccc ggcaagctgc agcgctgggg
    37801 cgggcctttt ttcgggagcc gcaacgagct gtggcgcctt tgtcaggagc cgatcacacc
    37861 gccgtcgttc ttcgtgatga tcacggtcgc cgaacgcggg cgggcgctgc cgccgtcggg
    37921 ccagttgctg ttgccaccct cacccgggtg ctggatgttg atgaacaggg tcttgctgtc
    37981 cggggtgaag gtgaggccgg tcacctcgca ttccttcggg ccgacgaaga agcgccggat
    38041 ctccttgctc tccggatcgg cacacagcat ctggttgttg ccctggcctg cgaagtcgcc
    38101 actgttgctg taattgccgt cggtctggat ccacagtcgg ccgtccttgt cgaagccgag
    38161 gccgtcgggg ctgttgaaca tgttttgggc ggtgacgttg ctcgaaccgg cacgcaggtc
    38221 gctgtgcacg gtcgggttgc ccgcgaggac gaagaggtcc cactcgaagg aggtcgccgc
    38281 cggatcgtcc gcagcctcgc gccagcgcac gatctggccg aagcggttgt tcgcgcgcgg
    38341 attcgcatcg tcggtcacgc ttcgaccgga gttgttggtc atcgtgacat agacctcaca
    38401 ggtcttcgga tggaccgcaa cccattcggg gcggtccatc ttggtggcgc ccaccgcgtc
    38461 ggctgccagg cgggtgttga ccagcacctc ggcctggttg gcgaagccgg cgagggcggc
    38521 gttcgccgcc ttgtcgagca ggatccactc gccggtgccc atgaagtcgc cggtggccgc
    38581 gccgtcgttg aacttggcga cgtagagctt gcccgagtcg agcaggttgg cgttgttgcg
    38641 gatgtctccg gcgacgtatt tcccgtccgc aacgaacttg tagacgtagt cattggcctg
    38701 gtcgtcgccc atgtacacca ccaccgtgcc gtcggcgccg atgcgatagg ctgcgttctc
    38761 gtgcttgata cgtccgagcg cggtgcgctt cttgggcgtc gagcgcgggt cgaaggggtc
    38821 gatctcgacg atccagccga agcggttcga ctcgttcggt tcgagctgcc agtcgaagcg
    38881 cgggacgtac tgctcgtact tgcgctctgt gccgttcgag tcgaggccgt agcggacctg
    38941 ggccgcgttg cgggcggtgc cgagggtgtt cagcgtgccg aagtactgat tgaagttctc
    39001 ctcgcaggtc aggtaggtgc cccacggggt gtagccgttg ccgcagttgt tcagcgtgcc
    39061 gaagacgagc gtgccggtcg ggtcggcgtt ggtctgcagc agcgtgtcgc ccgcggcggg
    39121 gccggtcagc agcatcggtg tgttgccggt gatgcggcgg ttgtaggccg agtcggtgac
    39181 gatctcccaa cgcccggcgg tgcgccggat gtggatcacc gagaccccgt gcgcgttgag
    39241 atccttgttg gcgtcgtcca ggctgtcgac ctgtccgttt gcgaacagcc agcgcacgtt
    39301 cgtgtactcg tggttcatca cgagcaggcc ttcgtcgttg ttcccttcgg tgagcgggaa
    39361 gaagtgcagg ccgtcgtggt tgtcgccgac ctggcgtgcc tgctccgcgg cgccctcgct
    39421 cgcgtcgccc gcccagctcg agccgggacc ggacgagaac agcggcgtgc cccagggcgc
    39481 gaacacggtg gcggtatagc cggcggcaac cacgatgtcg tcggcggtgg aggtcgggat
    39541 gccctcgaag ctcaggagcg gggtggcgac ggcggggggg ctggaaggcg agggggcgac
    39601 ggacgcgtcg tcatccgacg tacaggcggc cagcgatccc gacaggaagg cggcggccga
    39661 caggccgagc ccgctcttca gaaatccgcg gcgactgacc gcgcgtgcca cgacggactg
    39721 aaagtgctcg ttggccgaga ggttggtcgg aaagtcgtcg agcgtatcgg gcttcttcat
    39781 tgcttcacca ctccggatgc agggtcggga aagccttgag tgttcccgtg ccgggttacg
    39841 cgggcatgaa gggtttttta cggttcgacg agcgcacgca ggcgccgact gtggcgtgcc
    39901 ggagggggat tcagaaacgg atctggatgc gctcgccgtc gcgcgtcggg cgcagctcgg
    39961 cgagcatccc ctccaggcgg cctagcaagg gcgcattgcc gccgatctcg agctcgacgc
    40021 gcgggcgccg cccgcgcgca agctcgacct tcccattcac ggccagtgca agcccgcgca
    40081 gcgcggtgat ctccagcgtc gtcgccggtg cggtgatggt ggcgaccatg cgatgatcac
    40141 cgagcgcctg cccgggcagg atatccacgc cggcggcgct ccactccgcc tgcaagccgc
    40201 cctcgcagcg tccgctccag gtgcaggcga gcgcggggac gttcacgtcg agcacgccac
    40261 gccagccggc gcgtgcgatc gcatggggaa cggcggcgag cgcgacggcg ggtggcagct
    40321 gcaaggcgag gcgctgcagg gcgacgccgc cggggccgat ctccaggatg ccgggcgtgc
    40381 cgccgtcgat cgccagacgc cagcgcagcc ggacacttgc cagcgcggag ggctcgaatt
    40441 cccagcgcag gcgggtgatc gggctcagcg aagcgctgct gtctgcgctt gcgagacgcc
    40501 cctggccgtt ccacagcgtg cccgcggtca gcgcgagccg gaagcggccc gcgctggcac
    40561 ggtcgaggcc cgcgtcgagc agcaccgcgg gcgcgctcgc gacgagcagc acccccagcc
    40621 ctgcgcagaa gatggccgca ccggtcgcga acttcacctt ccgcccgcct cgaactccgc
    40681 gtcgaagcgc gcccggccgt cgctgccgac gggctgcaac tccagccggc tcggacgcag
    40741 gcgctgctcg gcgtgcaggg cggcgagcca gtcgatcagg gccggcaggg tgctgcggcc
    40801 gtcgacttcc accctttcgc ccaccaaccg cgcctcgacc tcgatcgcgc gcgcgcttgc
    40861 agcggcgcgg atcgagtcgg gcacggcggc gggcgggttg gctgcaggcg ccggatgctc
    40921 gcgcagcgcg gccaggccca ggctgtcctg ctccatgccg aggtaggcga ggcgggcggc
    40981 gggaaggctg cgcgcgagcc gttcgcgctc ggcgacgagg tgctcggcca gcgcgatcag
    41041 gccgccgccg agcacgaccg cggcggcgag cgccagcagg cggcgctcgc gcgtggcgcg
    41101 cgcggcgtac caggcgcgca accgggcggt cggcgaggtg gtgtccggac gggtgggcga
    41161 atgggcggcc gagggggccg gcgatcggcc ggatgcggtg ggggaggaag agggtgcgtt
    41221 catcgacttg ggctggggcg gcaccgattg ccgaggtcgg ccgggatcgc cgggctcgtg
    41281 gtgcgagggc tgggagggat ggggctgcgg gccatggacg ttcagggacg ggcggcgagg
    41341 atcagccgac tgccttcggc acgcgcggcc agcccgcggg cgtcgaggcg gacgagcagc
    41401 tcggcgggcg gtgggccagc cagctccagg gtgagtcggc cctcctcgta gcgtagggcc
    41461 tgcggctgcg gcgcgccggc ctcgagcgcg gcgtcgagca ggctcaggag gtcgccggcg
    41521 gcgagctgcc catgggcctg cagcgcgcgc tcatgcgcgc ggcgcagctg catgcgcggc
    41581 tcgagaaggg gctggccggg cagtgcctcg gcggccagct gctcgccgcg ttcgcgcaac
    41641 gcacgctcct cgcgcccgtc ggaccagacc agcgccgcct gcgccagcag ccacaccccc
    41701 gcggcactcg cggcgaggat cgccggcttg cgcaggcgcg gccaccatcc gtcgccgccg
    41761 tgcgccggcg cgaactcccc atgcagcagg ttgactgcgt cacgtgcggg ctgccaccag
    41821 tcgagcgccg gaccttcttc gacctcgagc ccgctccgta cggcgagcgc tgcagcttcg
    41881 gcaggcgacg cgccggccgc ggcgcgcagc tccaggcgta tggggcgcgc ctccgccggc
    41941 gtcgcgtcga gctgcagcgt caaccattca accagcgtgt cggcgctgtc ggcgtcgagc
    42001 gccatgccgg cgcgcgggcc ggtgcgcagc accgcggtgg cgccgggcag gacggccagg
    42061 gtccactgtc cgggcgccgg cggggcgagc tgcagcgcgc tgcgcaacgc gtcgagcggc
    42121 cggccgagcg ccttgcaggc ggcgaccagg gtggcgagct cgctgcgcgc gacgacgagc
    42181 acgccgacac gcgcgctcgc cgggtcgcgg ccgctgacgg tgagatgctg ctggtcgggg
    42241 tcgcgcgcga ggtggctctc gagcgcgtag cggatcagtt gcggctgttc gcgcttcggt
    42301 gcgggcggaa gctcgagctc gagccagagc acgcggctgc cggcgagcat gagctcgtgg
    42361 cggtcggctg cgggccagtg gcgcggatcg ctgcgcccgc ggtcgagcgg ccggcgcgcg
    42421 gcgtcgagca gcacccagtc ggcggtcggc tcctgtggcc agcgctcgcc ggcgagcagc
    42481 atgagggtgg tggtcatggc gtgtgatacc agaggatgct cggccagttc gactcgcggt
    42541 cgagcatggc ctgcaggttc agcaccgcgt cgccgtaggc ggcggtgacg gtgacgagaa
    42601 agtagcggct gcgcacgtcg agcacgcggc cggcgggcag gccggcgccc tcgggcaggc
    42661 ggccctggag gtcgccgagg ttgcggaacc aggcgcgctc gcgtgccgcg accaggttgc
    42721 gcgcggcgtc caggctcagg ccgtcgagta ccgcggcgag cacttccgcg ctcgcggtgt
    42781 tgatgttgat cgcagcgcca gcgggtgcag cgacgacgtg gggctcgagc gtgttgaagg
    42841 tggccgccgg caccagcccg agcaggacga gctcgcgtgt ctcgaccagc gcgcgtccgc
    42901 cgcccgcgtt tgtctcggcg ccgccaggtg cctcggaggc cgttgcggtg cgcgcatcac
    42961 ggccggcccc ggcgtcggcg gccccgccct gcaggtgggc agcgagcgcc tgcgctgccg
    43021 cgttcgcgct cgcgccgctc atgccgacga ggccgagcag gcgggcgaag cgcgtgacgg
    43081 cctgggtgtc cacacggccg cgcggcgcga gttcgttcag gttgaagcgt cccgagagat
    43141 cccggatcgc tccgcccacg ctgccgtcgg tgacgtcgct gccgatggcg gtgaccggga
    43201 tctcggtggt ccagatctcc ccgaggtggt cggtcggggt gcggcgcgcg tcgtcggcga
    43261 ggatgttgcg cgaccagtcc actgccgcgc gcccgagctg ccaggcctgg gcctggtcgt
    43321 ggcggccgcc gagcatgtcc aggccgtgac cgaagtcggc cagcgccgcc gcggcgagca
    43381 tggcggcgaa gctgaccgtc agcagcgcga gcaccaccgc ggcgccgcgc tgcgcggtcc
    43441 gcctagcgca gcgcgagaac gcggacgacg gtgccgacat cggcgagctc cagggtgaat
    43501 tccaccgcct cgggcagcgg ggtgacgatc gctgcacggc cacgcccgcg gctgcggttt
    43561 tcggcggccg gccactgcgt gtgcgcctgg ccggctgcga gcaggcgcca gcgcagggtg
    43621 tcgacgccat cgagcagggg caggcgcacc acctcgccgc gggcctcgcg gtcgggccac
    43681 acgagggcct cgaggcgctg gtcctggtgg cgcagctcga cgcggccaaa gccctgttcg
    43741 ccaccgatca cggtccatgc cagccggctg cggcggccgt tggggtcgcc ctcgagttcg
    43801 agcgcgggga gcgtggcgcc cgcagtggcc gcgctcgggc cggtgccctc ggcgagctgc
    43861 ggcggggcga tctgcatcag ctcgcgctcg atcagcgcgc tcgcgtgcac caccgcctgc
    43921 cagcgcgaca gctcggtgcc gatgcgctcg cgcgcatcga cgagctggct ggtggcgcgc
    43981 caggtcagca cgccgaccac gccgagcagc gccatcgcca ccatcagctc gatcagggtc
    44041 aggcccacgc cgcgccggcg cgcggcgcgg tgcggcactg cgcgcgggga gacgggaagg
    44101 tggcctcgcg gcatcgcctc gctcaacgca gtggccgcac ggcgaagccg ctcagggtgg
    44161 cgagggtgcg ttcgccgcgg gcgtcgagca cgcgcacgtc gatgcggcgg aagagcgcgt
    44221 tgggcgtgcc gctcaccttc tcctcccagc gcatcttcac gcgcgcctgc tcggcctcgc
    44281 cgcggtactc gccgatcgct ggccaggccg cggtggcgcg gtgcatggcc aggcggttct
    44341 gcgcgaccca gctggccagc gtgtgctcgc gcagggcggc ggtggactgg gcggtggcgc
    44401 ccatcgcgcg cagcgccgac accagcgcga tggcgacgat tgcgagcgcg accaggctct
    44461 cgagcagggt gaagccgcgc gcgcgcccgg cgtcgcgagg gcgggcccga atcccgcatc
    44521 tcgccgggtg ggtcgccgga ttcatcgtgc cggctccgcg ccggcaagtc gctccatccg
    44581 gccgtcgatg cggccggcga tgcggtagcg cttgccgtct tcggccagat cgagctcgaa
    44641 ggccggtgcg cgcgagccga agacgatccg ccggccgccg ccgtccagcg gggttgcggg
    44701 ggactctccc gccagggcgc ccgcagagta cgcatcttcc gaccccgcgc gcaacgcctg
    44761 ccggccgcct tgttcgccca cgcgcagcgc ggccacgcgc aggccgcccg cgaaggcgcg
    44821 cggggcgagc tcgggcggcg tctccagccg cttccagccg ccgtcggtct ggcgttcgct
    44881 gaagcggtag ccgtccggca gcaactccac cgccagcgcg cggccgcgca gctccgcacg
    44941 ataggcggcg ccctcgagcg cgcgccgcag gcgctcgacc tcgcgctcgc tgtcgtcggc
    45001 ctgggcgcgg tcgagcgcga gcgcgatgcc gccgccggcg atgccgacga tcaccagcac
    45061 gaccagcagt tcgacgaggg tgaagccgcg ctgcatgggc tcgcgatccg gggggaggcg
    45121 ggcgccgtgc tcagggctgc caggagccga tgtcggcgtc gaagccttcg ccgcccgggc
    45181 ggccgtcggc gccgtagctg aacacatcga cctcgccatg gacccccggc gccaggtact
    45241 ggtagggctg gccccagggg tccgcgggca ggcgctcgac gtaggccttc cagttctccg
    45301 gcgccggtgc ggcgctcggg cgcacgacga gcgcgccgag gccctgctcg gtgctcggat
    45361 agcgccggtt gtcgagcttg tagagcttga gcgcctgcat cagcgaggcg atgtcctgac
    45421 gtgccgcgac cacgcgcgcc tcgtcgggcc ggctcatgat gcgcggcacg accagggcgg
    45481 cgagcacgcc gaggatgacg atcacgacca tgacctcgat gagcgtgaag ccgcgggaac
    45541 ggtgggcggg gcggtcgacg cgggcagggc gggcgaagcg ttgctgcatg ggcttacctc
    45601 atcagggtgt tgatttcgat gatcggctgc atgaccgcga gcacgatcag cagcaccacc
    45661 gcgcccatca ccagcaagag cagcggctcg agcaggctgg tgagggtggc ggtgcgggtc
    45721 tcgagctcct gctgctgcag gcgcgcagcg cggtcgagga gctggtcgat gcggccggtg
    45781 gcctcgccgt tggccaccat gtggatcagc atcggcggga aggcgcgccc ggcggcgagt
    45841 gcgcgcgcga gcgggcggcc ctcgcgtacc tgctccgcgg cctcgcgtac cgcggcgcgg
    45901 atcggcaggc gctgcaccac gcggccggcg gcgtcgagtg cggcgagcag cggcacgccg
    45961 ctgcctacca ggatggcgag ggtgcttgcg aagcgggtgg cgtccaggct gcgcaggtgg
    46021 cggccgagca ccggcagcgc gagcaggcgg cgatcgaagg cgtggcggat gcgctcgtcg
    46081 cgcagcagcg cgagcgcgcc gaggagcgcc gcggggcccg cggcgagcgc gagccagccc
    46141 cagtcgcgga tgaagttcga cgtcccgatc atgatgcggg tcagcagcgg cagcgcctgc
    46201 ttgctctgcg cgaacacgcc caccacctgc ggcaccacga agaccatcag cccggtcacc
    46261 accagcagcg ccaccaccgc caccagggcg ggatagatca gcgcctgcat cgtcttgcgc
    46321 tgcaggtcgg cgccgcgctc gaggtggtcg gcgagctggt tcatcaccgc ggcgagctcg
    46381 ccggactgct cgccggcggc gatcgccgcg cggtagatcg gcgggaaggc gccgctgtgg
    46441 cggtcgagcg cgatgcgcag gctatggccg gagacgacgt cggagcggat cgccgccaag
    46501 gtgtcgtgca cgcgctcgct ctcggcctgc tcgatcagcg ccgacagcga gtgctcgacg
    46561 gtgagcccgg cggcgagcag ggtcgcccac tgccgcgaca gcagcgcgag ctcgttcacc
    46621 ggcaggcggc ggcgcgcctg cacacgggcg agccagcccg ggcgcccggc ggcggcgcgc
    46681 gcctgctggc cgagatcgat gacctcgacc ggatgcaggc cgcgctcgcg cagcgcgctg
    46741 cgggcggcac gaccggagtc ggcctcgatc acgccggtgc tcggtgtgcc ctggaggtcg
    46801 aaggcgcggt agcggaaggc gctcatcgca gcgggctcag gcgcggatca cgcgctgcag
    46861 ctcggcggcg ctggtcagcc cgctggcgac gtggcgcagg ccgtcctcgt gcaggctgcg
    46921 catgccggcg gcgcgcgcgt gggtgcgcag gcggtcttcg tcggcgccgt cgtggatcag
    46981 ccggcgcagg gcctcgtcga ccaccagcag ctcgtagatg ccggcgcgcc cgcggtagcc
    47041 gctgtggccg cagtgcccgc actggccggc ttcccagccc tgcatcgttg tggcgggttg
    47101 gcggcagtcg gggcagagct tgcgcaccag gcgctgggcg agcacgccgc gcagggtgga
    47161 ggcgagcagg aagggctcga tgcccatgtc caccaggcgg gtaagcgcgg cggcgctgtc
    47221 gttggtgtgc agggtggcga gcacgaggtg gccggtgagg ctggcctgga tggcgatctg
    47281 cgcggtctcg aggtcgcgga tctcgccgat catgattacg tccgggtcct ggcgcaggat
    47341 cgcccgcagc gcgcgcgcga agtcgagctc gatgcgcgga ttgaccgcga tctggccgac
    47401 gccgggcagg tcgaactcca ccggatcctc gacggtgacg atgttgagcc gggcggcgtc
    47461 caggctctgc agcgcggcgt acagcgtggt cgtcttgccc gagccggtgg gaccggtgac
    47521 gagcaggatg ccgtgcggct ggccgagcag ttcggtgaag gcggcgccgg tcgtgggcgc
    47581 catgccgagg ccgtcgagcc cgatccgccc ggcctgcttg tcgagcaggc gcagcaccag
    47641 gcgctcgccg tgggtggtgg gcacggtgga cacgcgcacg tccaccgcgc gcccggccag
    47701 gcgcagggtg atgcggccgt cctgcgggag gcgtttctcg gcgatgtcga gctgcgccat
    47761 gatcttgatg cgcgaggcca tcgccgcgtg caggccgcgg cgcgggcggg cgatgtcgcg
    47821 cagcacgccg tcgcggcgca ggcgcaccac cgactcgcgc tcgtagggct cgatgtgcac
    47881 gtccgaggcg ccgtcgcgca cggcctgggt cagcagggcg ttgatcaggc ggatgatcgg
    47941 cgcgtcgtcc tgggtgtcga ggaggtcctc gaccgcgggc agctcggtca tcaggcggtc
    48001 gaggtcgacc tcctggccga cgtcggcgac cacctccgcg gcgctgccgc cggcgccacc
    48061 gtaggcctcg gcgaggcggg cgtcgaactc tgcgcgcggc acgcgctgca ggcgcagcgg
    48121 caggccgacg ctgcggcgca cctcggcgag cgcctgcggg cgggcgtcct cgcgcaccag
    48181 cacctcggcg tgctcggcgc cgagcgcggc aaccagtacg ccgtggtcgc gggcgaagcc
    48241 gtagggcagc tcgaaaccca tcagcgcggg gccactggcg aggcggcacg ctgcagcggc
    48301 cggaaggcga ggtcgaccac cggcgccggc tcgcccggcg gcgggtcgcg cagcaggttc
    48361 gacccggagg gcagctcgtc gcggcgaccg atcacgtagt cgtagcgact gtcggtgagc
    48421 gcggcgtagc tgtcgcggtc gcgcaggatc accggacgca ggaacaccac caggttggtc
    48481 ttggagcgct tgcgcgtgtc gtagcggaac aggctgccgg cgatcggcag gtcgcccagc
    48541 accggcacct tctcctcgcc gccgctgtag ctgtcctcga ccaggccgcc gagggcgagg
    48601 atggcgccgt cgtcgaccag caccatggac tcgatcgagc gcttggtggt gaccgagttg
    48661 ccggcggccg cgctctccgc gctgcccacc accgccgagg cctcctggta gatctgcagg
    48721 cgaatggtgc cgccctcgga gatctgcggc ttgacatgca gggtgaggcc gacgtcgcgg
    48781 cgctcgatgg tctggaaggg gttggcgggc gtggtgccgc cgccggtgtt ggcgtactgg
    48841 ccggtcacga agggcaggtt gcggccgacg acgatgcgcg cctcctcgtt gtcgagggtg
    48901 atcaggttgg gcgtggacag gatgttggcg ctgacctcgt tctcgaggaa gcgcgccagc
    48961 acgcccaggc tcaggacttc gccaaggccg gggacgttga ccttgccgcc gccgacgacg
    49021 aggttgaggc cgttgttggg cagggtcggt gtgccgttgc cggaggtgcc ggcgatgagc
    49081 tggccgaggt tgctgccgcc gctgttgaag atctgcccac ccaggatgcc gaccttgccc
    49141 gaggcgccgc cgcccaccca ctggaaaccg aactcggcgg cgcgctcggt ggagatctcg
    49201 gcgatcagcg cctcgatgta gacctgcgcg cggcggcggt cgagctggtc gatgaccgcg
    49261 cgcaggttgc gatagaccgc gtcgggcgcg gtgatgatca gcgcattgtt gaccgcgtcc
    49321 ggctgcacca tgccgccgcg cgtggcggaa gaaagtccgc ctgccgtggt gctggtcgcg
    49381 gcgcccgtgc cgcgcagggg cgcgctggcg acgcccatcc cggacgcggc cgaactgccc
    49441 gtgccgaacc caccgccgcc gttgcgcgac agcggctggg tggtggcggc ctcgctcgtg
    49501 ccgccctcgc cggcgagcgc ggcgttgagc gtggcggcca cctgggtggc gtcggcgttg
    49561 cgcaggtaga ccacgcggat gtcgccgccc gcgccgggac ggtcgagcgc gatgacgagc
    49621 tggcgcaggg ccgccaggcg gctgggcgtg tcggcgcgca ccagcaggct gttgctgttg
    49681 ggttcggcga cgatctgcgg cggcgcgagt ccgccggcgt tctggccgcc ggcttgctgt
    49741 tcggcgagca ggcggacgag caccggggcg aggtcgttgg ccatcgcgtg ctgcaggtgc
    49801 agcacggcga cgtcgccctg cggggtgtcg atcgagtcga tcaccgtcgc cagccggcgc
    49861 aggttctcgg cgtagtcggt gaccaccagg gtgttgttgc ccgggaaggc ggtgacggcg
    49921 ttgttggccg agaccagcgg gcgcaccacg ttgaccatgt gcgccgccga ctcgtggcgc
    49981 agcgcgaaga cctgggtcac caggcggtcg ccacgtgcgc cccctgcgcc ctggcggccg
    50041 ctcaccaccg gaacgccgtg cagcttggcg tcggcctcgg gcacgagctt ggtcacgccc
    50101 gactcctcga tcgccgcgta accctgcagg cgcagcgccg agagcaggat ctggtaggtc
    50161 agctcgggcg ctaccggggt gttggtgatg aggttgatct tgcccttgac gcgcggatcg
    50221 atgaggaagt tgcgccccga gatgcgcccg atcgcctgga tcaccgagtc gatctcggcg
    50281 ttctggaagt tcagcgccac cggctcgcca gcggcgtgcg ccg
//
LOCUS       DAOTIN010000014        50023 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_719_length_50023_cov_9.246898, whole genome shotgun sequence.
ACCESSION   DAOTIN010000014 DAOTIN010000000
VERSION     DAOTIN010000014.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 50023)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 50023)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50023
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_719_length_50023_cov_9.246898"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..858)
                     /locus_tag="P5537_03770"
     CDS             complement(<1..858)
                     /locus_tag="P5537_03770"
                     /EC_number="2.4.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324925.1"
                     /note="catalyzes the formation of thymine and
                     2-deoxy-alpha-D-ribose 1-phosphate from thymidine; Derived
                     by automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine phosphorylase"
                     /protein_id="HRV77193.1"
                     /translation="MDAQAGIPAVAAESASPLRLRRVAIDTWRENVVYLHRDCAIYRA
                     EGFQALSKVEVRANGRRILASLNVVDDGCIVQPDELGVSIDAFIQLGVDDGHPAMIAQ
                     AEPPSSIPALRRKIAGERLARDDFRAIVRDIAEHRYSKIELTAFVVATNQGELDREEV
                     AFLTEAMAAVGDRIDWREHPVVDKHCIGGIPGNRTSMLVVPIVAAHGMLCPKTSSRAI
                     TSPAGTADTMEVLACVELPTEVLSGIVREHRGCLAWGGTANLSPADDVLISVERPLSI
                     DSPGQMVASI"
     gene            1092..1514
                     /locus_tag="P5537_03775"
     CDS             1092..1514
                     /locus_tag="P5537_03775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HRV77194.1"
                     /translation="MTNRNISFIVKDQNPLMLRPSDTVQAACRSMCERSVGAVLVTDA
                     RAHLKGIFTGRDAVQVIANGGDPAKVHLSEVMTAKPDTIEPERKAIDALHMMCDGGYR
                     HLPVVVDGKVVGIVSRSDFKGLELDQFEDEQSLWERIC"
     gene            complement(1582..2673)
                     /locus_tag="P5537_03780"
     CDS             complement(1582..2673)
                     /locus_tag="P5537_03780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5924 family protein"
                     /protein_id="HRV77195.1"
                     /translation="MKDESYPSTESLVASLQETDSATSGSRLARLKEGGLRLVVWLRR
                     HPWLIATFGFVSGVLSFFLVERHEGVARAMAVAMLAGWLLLVLERVLDRAVKRRFGFG
                     LPPVLVRYLTQFTHQESLFFALPFFFASTSWNSGQAVFTGALGLMALVAILDPVYFGR
                     LATRRWLFLGYHTLTLFALLLVLFPLVLQVPAMASYQLALAVAVVLSFPTLAGAISVP
                     RWWRGLLVLALLAALGAAGWLARLWVPPATLRLTQVAVTSVVDEAQRAPAESLRSIEA
                     GRLLAEGLYAYTAIHAPLGLSEKVVHVWRHEGQVVDRIELEVSGGRAEGYRAWTRKRN
                     FPEDPRGRWQVQVLAADDRMIGTLRFGVE"
     gene            complement(2670..3410)
                     /locus_tag="P5537_03785"
     CDS             complement(2670..3410)
                     /locus_tag="P5537_03785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002945020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HRV77196.1"
                     /translation="MRGMRAVLTGHSRGLGEAIAEELLDRGIAVLALARRGNPALAAR
                     HGERLCEVAVDLADSAALAAWLGSGALQAWLAEADEALLINNAGTLQPMGPLALQDPM
                     AVARAVAANVGAPLALAAAFAAAAGPQARRVLHVSSGAARKPYAGWSVYCATKAALDH
                     HARAVQLDAVPGLRICALAPGVIDTGMQAEIRASTPERFPLRDRFAEMQASGGLVAPA
                     ECAMHLVDFVLDEDFGREPVADLRDLGR"
     gene            complement(3407..4057)
                     /locus_tag="P5537_03790"
     CDS             complement(3407..4057)
                     /locus_tag="P5537_03790"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004385457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HRV77197.1"
                     /translation="MNAHEQEHMWSTRYRSAGEDYVFGTTPNRFLAAQAALLASGADA
                     LSVADGEGRNAVWLAEQGLAVTATEISPVALEKARKLAAGRHVEVDFVLADAVAWDYP
                     EAAFDFVVAIFIQFADSAQRAHIFAGMARALRPGGHLILQGYTPKQLEYRTGGPSAVE
                     NLYTAELLREAFAGLEIVHLQEYEDVLEEGVGHKGRSALVGLVARRPADAAAEPGR"
     gene            complement(4098..4841)
                     /locus_tag="P5537_03795"
     CDS             complement(4098..4841)
                     /locus_tag="P5537_03795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HRV77198.1"
                     /translation="MSSSVGEAARAGGRAQDADGRSLAVVVGSGGGVGAAVVAALREA
                     GDYDEVLALGRRGSPALDLLDEASIAAAAAAVRARGVPTLVFDATGFLHGGGMEPEKS
                     WRELDPAHLAHAFAINAIGPALLMKHFLPLLPRERRAVFATLSARVGSIGDNRLGGWY
                     AYRASKAALNQLVRTAAVELRRSRPQAICVALHPGTVDTGLSAPFAKSGLQVQAPAEA
                     AARLLAVIGRLGPNDSGEFFDHRGEPVPW"
     gene            complement(4838..6223)
                     /locus_tag="P5537_03800"
     CDS             complement(4838..6223)
                     /locus_tag="P5537_03800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002925952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HRV77199.1"
                     /translation="MSIIERALAKAKQQDRAAVEDAEGLVHRAQADPGADVGPARGPG
                     DAPDVGEGTALPATATATAPGARDETPRDAGPAGEPQGRELAPAQLPAPGLAPTGAED
                     AMASAPAAPAAAAARRVRDPGAAAPLLRVEDLRCAFDVSRPWLERLLAREPRRWLRAV
                     DGVSFAIPRGRTFALVGESGCGKSTVARLIVGLHEPSAGRVVFDGRDLAEVRGSAERQ
                     KLRRRSQMIFQDPYASLNPRWRVERIIAEPIRVFGLEKDDAAIRARVAGLLGQVGLSP
                     ADGAKYPHEFSGGQRQRICIARALANRPEFLVCDEPTSALDVSVQAQILNLMRDLQDA
                     LGLTFLFISHDLAVVRHMADEIGVMYLGRIVEIATSRRLFERPRHPYTRMLLATIPDF
                     SRRGRADDAVRGEVPNPITPPTGCTFHPRCPLADARCRQEVPALRELDDGGRVACHAV
                     EEGRDNLEAGS"
     gene            complement(6220..7248)
                     /locus_tag="P5537_03805"
     CDS             complement(6220..7248)
                     /locus_tag="P5537_03805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV77200.1"
                     /translation="MNVPHIDQMNAGGGLPLLSVRRLRVEFPSRRGTLLALDDVSFDI
                     ARGEVLGVVGESGAGKSLTGAAIIGLLEPPGRIAGGEILLDGEAIHELSGEAMRRLRG
                     RRIAMIFQDPLTSLNPLYTVGEQLVETMLTHLELTPAAARERALALLDEVGIPAPAQR
                     IDHYPHQFSGGMRQRVVIALALCAEPELIIADEPTTALDVSVQAQIIALLRRLCRQHH
                     TAVMLVTHDMGVIAETADRVAVMYAGRVVEIGPVDEVVCAPAHPYTRGLMGAIPVLGD
                     EVERLVQIDGAMPRLDAIPPGCAFHPRCAAAFARCRIECPELQPAGATRAACWLYAPA
                     EMAEGGGR"
     gene            complement(7245..8213)
                     /locus_tag="P5537_03810"
     CDS             complement(7245..8213)
                     /locus_tag="P5537_03810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV77201.1"
                     /translation="MRTEPPTSAPAAAPPVPRGALARLLDGDLFHSFIRSPITVLSAL
                     VVLAILVAALLAPVIAPQNPFDPATLNLMDGFTRPMQANEFTGNVYWLGTDAQGRDLF
                     SAILYGSRVSILVGFAAVAFAAVLGITLGLVAGYRGGWVDSLIMRVADVQLSFPAILV
                     ALLIFGVFKGVVPPALHDKAAIYVLILAIGLSDWVQYARTVRSSTLAERNKEYVQAAR
                     VIGVPAPTILLRHILPNVMGPVLVIATIGLALAIILESTLSFLGVGVPPTQPSLGTLI
                     RVGQDYLFSGEWWIVLFPGLTLLLLALSVNLLGDWLRDALNPRLRR"
     gene            complement(8240..9223)
                     /locus_tag="P5537_03815"
     CDS             complement(8240..9223)
                     /locus_tag="P5537_03815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004389307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV77202.1"
                     /translation="MPAFILRRLLQSVLVMLTVALVAFGLFRYIGDPVNNMVGQEATM
                     AEREALRESLGLNDAVPLQFLRFVANAAQGEFGVSYRMARPVADVIAERLPATLELAL
                     ISGFGALALGIALGVYTALRRDGWLSHAIMGLSLVGVSLPTFLIGILLIYVFAVELKV
                     LPAFGRGEVVDLGWWTTGLLTPSGLKSLVMPAITLGLYQLTLIMRLVRAEMLEVLRTD
                     YIKFARARGLSDRAVHFGHALRNTLLPVITITGLQIGSIIAFAIITETVFQWPGVGLL
                     FITAVQFVDIPVMAAYLVLIALIFVVINLIVDLLYFVVDPRLRVQRSGRGQ"
     gene            complement(9293..10888)
                     /locus_tag="P5537_03820"
     CDS             complement(9293..10888)
                     /locus_tag="P5537_03820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HRV77203.1"
                     /translation="MNKTRLALALPFALATLAGMAATPASAQTVRWAAAGDALTMDPH
                     AQNEGPTHVMNHQVYDSLVFRDQAMKLAPRLATSWKITDDPNVWEFKLREGVKYHNGN
                     PFTADDVVFSILRAKHENSDMKGLLTSVVEVTKVDEHTVRMRTDGPNPLLPNNLTNLF
                     IMDREWSEANKVTLPQNYKAGDETYAVRNTNGTGPFRLVKREPDVRTELERNEDYWGK
                     GSYPMEVAKVVFTPVRSAATRVAALLSGEIDFLLDPPVQDLERLSAAKGIVVRSGPEN
                     RTIFFGMNQGATELRSSDVKGRNPFADKRVREAMNIAINREAVRRVVMRGQSVPAGIV
                     APPFIDGYDKAMDVVPAPDVARAKALLAEAGYPDGFAVTLSCPNDRYVNDEAICQAAT
                     GMFGQIGVKARLDARPKSIHFAELPKGELDLYMLGWGVPTMDSHYVFHYLYETRTDKG
                     GSWNVTGYSSPRVDELTKAMNREIDLGKRAGMVAETWKTVQDDIVYLPIHHQMLNWAM
                     KDDIDFPVQSENYPYFKLLKYRK"
     gene            complement(11056..11517)
                     /locus_tag="P5537_03825"
     CDS             complement(11056..11517)
                     /locus_tag="P5537_03825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopD family protein"
                     /protein_id="HRV77204.1"
                     /translation="MDLHPLLLFLHVAGVVVWVGGMFFAYVCLRPEAASQLEPPPRLR
                     LWRGVLARFFTWVWVAVAAVLVSGLALILRYGFAAAPLYQHIMFLMGLVMIAIYAFVF
                     FTPYAALTRAVVAEDWKAGGAALGRIRQLVGTNLTLGFLTIAMGTIGRWLG"
     gene            complement(11600..12205)
                     /locus_tag="P5537_03830"
     CDS             complement(11600..12205)
                     /locus_tag="P5537_03830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04282 family arsenosugar biosynthesis
                     glycosyltransferase"
                     /protein_id="HRV77205.1"
                     /translation="MSATRIVVFAKAPQPGRVKTRLIPALGADGAAALAARMLARTLA
                     AAAEALPGGLELCASPAPGDPAWRGLTVPAGLRWSAQGEGDLGARMAGAARRVLAGGE
                     RVLLIGTDCPALDAACLRAAAEALDEVEAVIVPSFDGGYVLLGLRRFDPRLFEGIAWS
                     TPTVAAETRARIAALAWSCRELPALHDIDVPADLVHLPSGA"
     gene            complement(12202..12900)
                     /locus_tag="P5537_03835"
     CDS             complement(12202..12900)
                     /locus_tag="P5537_03835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004385713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04283 family arsenosugar biosynthesis
                     glycosyltransferase"
                     /protein_id="HRV77206.1"
                     /translation="MAAPQVEERAEALAIVVPMLDEAATLPALLVHLAGWRARGCEVV
                     LVDGGSRDDSVEMARAAGFRVLIAERGRARQMNAGAQACGRALMLFLHADTRLPEAAD
                     AMVCAALAVQAWGRFDVHIDGRPRMLRVVAALMNLRSRLSGIATGDQAIFVRRDVFEA
                     VGGFPDQPLMEDIELSCRLLRVSRPACLRARVRTSGRRWEQRGVWRTIALMWRLRWAY
                     WRGVPAERLAEAYR"
     gene            complement(12903..13892)
                     /gene="arsS"
                     /locus_tag="P5537_03840"
     CDS             complement(12903..13892)
                     /gene="arsS"
                     /locus_tag="P5537_03840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004327695.1"
                     /note="Some members of this family are selenoproteins;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arsenosugar biosynthesis radical SAM protein
                     ArsS"
                     /protein_id="HRV77207.1"
                     /translation="MHATLPLLESRRFPALRREATTTLQVNLGYRCNQSCVHCHVNAG
                     PNRSEMMDADTMALIPQVLAARAIGTLDLTGGAPELHPGFRALVREARALGVRVIDRC
                     NLTILSEPGQEDLAEFLAGQDVEVVASLPCYSADNVDRQRGKGVFERSIAGLLHLNAL
                     GYGQPGSGRVLNLVYNPQGPVLPPDQARLEADYRRELAAHFGIVFNQLFALANMPIQR
                     FGSMLISKGQFNAYMELLQAAHRDENLAAVMCRSLVSVDWRGRLYDCDFNQQLGLPAG
                     DGDADAAGAARPGALHLRDLLAADLAGASIRVADHCFGCTAGSGSSCGGALKG"
     gene            14067..15215
                     /locus_tag="P5537_03845"
     CDS             14067..15215
                     /locus_tag="P5537_03845"
                     /inference="COORDINATES: protein motif:HMM:NF019604.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HRV77208.1"
                     /translation="MKRLLLVGGGHAQLAVLQALARQRPRAVEAVLLTPSPWQWYSGM
                     LPGWMAGHYRAEDCRIDLRPLAAAAGVRLCLAAAVALDADRRRLQDDSGAIHDFDLLS
                     LDVGSLTDTHALEALPAGTLLPVKPLQAFFAAWPQRLAAARAGQLHRLAVVGGGAAGV
                     ELVLAAAQAFRGASCTVALALVAPPGGLLAGHAEGVRRRVERRLAQAGIALHLARAGG
                     TAAGLVLDHGAGDAPAALPADCVIAATGARALPWLRESGLACDADGWVAVDAGHRSLS
                     HPAIHAAGDVCTRAVPGFARSGVHAVHAGPVLAANLLAALESGPASTPPHTYRPRPRS
                     LYLIASGPRHAIASWGCWSAEGRWVWHWKAYLDRGFIARHRRAAIVPV"
     gene            15288..16418
                     /locus_tag="P5537_03850"
     CDS             15288..16418
                     /locus_tag="P5537_03850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HRV77209.1"
                     /translation="MHELVQDYYGRTLQSSADLKTSACCDASALPAALKPVLGRIHPE
                     VLARYYGCGLVSPPLLEGCRVLDLGCGSGRDVYALAQLVGERGEVVGVDMTPEQLAVA
                     RRHEDYHREAFGFARSNVRFLEGYIERLGELGLEDASFDVIVSNCVINLCPDKAAVLR
                     EVFRLLKAGGEFYFSDVYADRRVPAAVRDDPVLYGECLGGALYWNDFLALARAAGFAD
                     PRLVEDRALAVTDPALAARLGNIRFFSATWRLFRIDGLDSAGEDYGQAVVYRGTLTGQ
                     PERLALDKRHAFDAGRVEPVSGNTWRMLHDSRLRPHFDFVGSFERHYGLFAGEGLAMP
                     FDTASPAAGGDSPATPAPTPSPTPSPTPAPATLGSATRKSCC"
     gene            16444..18612
                     /locus_tag="P5537_03855"
     CDS             16444..18612
                     /locus_tag="P5537_03855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HRV77210.1"
                     /translation="MKKALLLLLVLALAAAFFASGLHRQLDLDALKAGMGSFAAWREA
                     SPLLVAALYFAAYVAVTALSLPGAAVMTLAGGALFGLGWGLLIVSFASTIGATLAFLV
                     SRHLLRDSVQARFGERLKAINDGIARDGAFYLFSLRLVPAFPFFLINLLMGLTPIRTR
                     TFYWVSQLGMLPGTLVYVNAGTELGAVDSLAGVLSPGLVASFVLLGLFPLLARWLLAR
                     VQARRVYAGWTRPKRFERNLVVIGAGAAGLVTSYIAAAVKARVSLVEAGRMGGDCLNT
                     GCVPSKALIRSARLAHHIRHAERYGLTAGEPTIDFRRLMARVRAVIRKIEPHDSVERY
                     TALGVEVLQGRARIVDPWTVEVALNEGGTHRLSTRNIVIATGARPTVPALPGLEAVGY
                     LTSDTLWDALAELDAPPRRLLVLGGGPIGCELAQACARLGSQVVLVGRAPQLLPREDA
                     DVAAFARAALEADGVEVLTGVVALRCELEQADDGARKFLVVADPASGSERRIGFDFLL
                     CAVGRSARLEGFGLEALGIPTGATVETNDFLQTRYPNILAAGDVAGPFQFTHVAAHQA
                     WHAAVNALFGHLRRFRVDYRCVPHTTFIDPEVARVGLNEAEARARGIAFEVTRYGLDE
                     LDRAIADGADHGFVKVLTAPGKDRILGATIVGEHAGELLAEFVLAMKHDLGLNKLLGT
                     IHAYPTFAEANKAAAGEWKRAHAPQRVLRWLERHHAWLRG"
     gene            complement(18626..19879)
                     /locus_tag="P5537_03860"
     CDS             complement(18626..19879)
                     /locus_tag="P5537_03860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HRV77211.1"
                     /translation="MSSTDASPRLGGHAPSAAAGIPPAFVVIIAGMVAALHIGKIPPA
                     IPVLRDALGLSLVEAGFLLSMVQMAGMLGGVFIGLAADGFGLRRSVLLGQAVLVAASL
                     AGAWATQPGELLALRAIEGFGFLLCVLPVPSLIRQLVPPSRLALHLGLWGTYMATGTS
                     LVLAAGPLLMGAIGWQGLWVALAMASAAVAGWLFLRVPSDRVRRAMAAMPAGAAVPAR
                     AQWRARLRATLGSVGPWRVAITFSVYSSQWLAVIGFLPAIYAQAGLSGQLAGLLTALA
                     CLSNVTGNVAAGRLLHRGVCARHLLYAGFLAMAATAFVAFSPLTAEAPVARYLAVVLF
                     SAIGGLIPATLFALAVHVAPDEHTVSTTVGWMQQCSSAGQFLGPPLVAWVAGMVGGWQ
                     WTWVITGLASLVGLVLSSRMRYQRA"
     gene            20042..20875
                     /locus_tag="P5537_03865"
     CDS             20042..20875
                     /locus_tag="P5537_03865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HRV77212.1"
                     /translation="MTSPHPEIRPGQSVELLKQLHILTRDGKLNQDSRRKLKQVYHLY
                     QFIEPLLAEALAERPDIELVDHGAGKSYLGFILYDLFFKAQAPDGRIHGIETRDELVM
                     SSRRLADKLGFSAGMRFQNLSVADSISSDRLPARIDIVTALHACNTATDDAIRFALKK
                     GARAIVLVPCCQAEVAAVLRRNKQQALRDPIAELWRHPIHTREFGSHVTNVLRCLQLE
                     AHGYEVTVTELVGWEHSMKNELIVARRQPDRPRQRAAERLAALLGMLGLEELSERFFT
                     G"
     gene            21094..22089
                     /locus_tag="P5537_03870"
     CDS             21094..22089
                     /locus_tag="P5537_03870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ankyrin repeat domain-containing protein"
                     /protein_id="HRV77213.1"
                     /translation="MAETESPLAFLLTTPYANRYPRKLVEGFPHVARRIAELWDDKDK
                     LGEYFTELMVSNRPNRRGFPPEVGAEIVYLSMAYDLHGPVRPTAQAAPEATTSPREDA
                     WDHERAVTELERLDIPVTMAQFVRALEAGDQPLCSLFLHAGFDVDSRDARQWTPLMIA
                     CFHGREALALELIRLGASVDAQDADGYTPLHWASVNGYQKVGEVLVRRQAEVNAVSKA
                     GITPLLQAAARGHLGVVRLLIERKAKLNLAATDGSTALLKAVANGHWEIVNTLLDAGA
                     STQATMKNGTTLVDIAARSKDERIRERIAIAARMEARGDAPIQRDEPPPLTGTIY"
     gene            22108..23286
                     /locus_tag="P5537_03875"
     CDS             22108..23286
                     /locus_tag="P5537_03875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug effflux MFS transporter"
                     /protein_id="HRV77214.1"
                     /translation="MVGIPSAALAVLVVALTSLGPLSTDFYLPALPAIARALHTDSAG
                     VQLTLSVYLLGFGAGQLLVGPLSDRFGRRPVMLWGMLVFLLSTLACVFAESLAVLVGA
                     RLLQAFGACAGPVLGRAVVRDLYGPAESARMLSHVSTATALAPLLAPLLGGWLTAAWG
                     WRATFVALAVYAVLLMLAVAMLLRETNRHPDADAMRPGRMLANYRTLLADPAYRGALL
                     IGCGAFAALFAFISGSPFVFIEHFGLSPQQMGLAFGLNVTGFMIGTTLSARHSRRLGP
                     ARLIRHGVWIGAACGVLLAALAVAGPQHPAAVMLPMWGVTAAIGLILPNATALGLAGY
                     PKMAGAAASLMGFVQMGLGAGAGMLVGHGVQHGTAALGLTVAGGMLFALAAWSRSPAR
                     "
     gene            complement(23300..26350)
                     /locus_tag="P5537_03880"
     CDS             complement(23300..26350)
                     /locus_tag="P5537_03880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HRV77215.1"
                     /translation="MKLVSAADAADPGRRHAGWRLAFPLIALTVLVAGVGAFGYRSLS
                     EEIRRETQRTLAVIAEQKRQHIEGWLAEARVDAQMVFSGHSQLEALFAGWVDGGRRDE
                     VAYARMQALVEELVRLRGWQGLALIDAEGAPALVVGSPDLSTHAERIADVLRRPRVEF
                     VDLHEDAQGRTHYGVLAPVGVPARGVAYLSWEAEAALYPMVEAWPVPTRSAETYLVRR
                     DGEGVRFLTPLRHQAGAALALERPLATPDLPAARAALGERGILSGGRDYRGVPVLAYA
                     AAVEGTPWLMLAEIDEREAYAGIRTLTWGMGVVMALGLMLVYSAGYLVWRRDREQRER
                     AALQARQAAEARFRVIFEQAPLGVVLLDPRTRRITEANPRFAEIVGRGVGELVGADPM
                     ALTHPDDVAESLRQLGRLDARRIDGYRLNKRYLRPDGTPVWVSLAFAPVQVASEDAPR
                     YLGIVEDISARIEMEERLRQASAAAAAANAAKSEFLAHMSHEIRTPMNAVLGLAQVLE
                     REPLAPAQRDMVGRIRGAGQSLLAILNDVLDLSKIEAGQLRIEPRPFDLRALLANLDS
                     LMGQAARAKGLALRIEPPALPPGQLRGDGLRIEQILINLVSNAIKFTERGEVSVRVRT
                     DEVEEAQLRVHAEVRDTGIGIAPEAQARLFAPFTQADAGIARRFGGTGLGLSICKRLV
                     ELMGGAIGVRSQPGLGSTFWFELPLERVAGSEPASAAIPAPAAASASGSRLAGMHVLV
                     VDDSAMNRDLVQRALALEGAEATLAADGQQAIELLRSRPRAFDAVLMDVQMPVLDGLS
                     ATRRIRDELGLAALPVIAFTAGVGADQQAAARAAGADDVLPKPMDLEQMTLLLLRWVE
                     PTGLREATPASGADAVRAIAAAAMPVFAPETALPVQAAAAASATAGDEFPVLPGIERE
                     RAMQRLGKDRDMFLGLLGLFIEDNAGVVAATRADLACDEREAAARRMHTLRSNAGFIC
                     ALAIMEAAEALEKAIAQDEPGVAARLDALEADIAGLVAAGRALL"
     gene            complement(26451..27320)
                     /locus_tag="P5537_03885"
     CDS             complement(26451..27320)
                     /locus_tag="P5537_03885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HRV77216.1"
                     /translation="MMCASSACGWQACLARGLAAFAVVVAATFSLPAVALELPRERAV
                     AGGVALVELGPALVAPQASLDGVPVLVAGRPGGWTAVVGIPLEAAPGSLELELRAEDE
                     PPRRLPVAVGPVRYAEQRLKVAPGKVDLSPVDLARHERERLRSAEIVATWSALDPGSL
                     RMLQPVPGRRSGSFGLRRVFNDQPRKPHGGMDIAAPTGTPVVAAAAGRVIDTGDYFFN
                     GNTVWIDHGRGLLTMYCHLSSIAVKAGDTVEAGARIGAVGATGRVTGPHLHWSVMLNR
                     TMVDPALFLAGGG"
     gene            27530..28975
                     /locus_tag="P5537_03890"
     CDS             27530..28975
                     /locus_tag="P5537_03890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HRV77217.1"
                     /translation="MEAFANQVVDLLNGLLWGKILIWLLVGTGIYFTLRLGFIQLRHF
                     GHTFTVLRGSRRSDASGISSFQALCTSLAARVGTGNIAGVAVAITLGGPGAIFWMWVI
                     ALVGMATGFAEATLAQLFKQRDDKGQFRGGPAYYMEKGLGQRWAGTMFSIFLIIAFGF
                     AFNSVQSNTIASAMVGAFGLDLGSLTLGGNEVGVAALVIGVAVTVLTAAIIFGGLRSI
                     ARFSELAVPFMAVGYLVVAVGIILANLGEVPGVLALIFQSAFGLHEAAAGGIGAAILN
                     GFKRGLFSNEAGMGSAPNAAAAATPYPPHPASQGYVQMAGVFIDTMLICTASAAIILL
                     AGPVEGTGVGLVQNALTSEVGGWGKYFLAIVVLFFAFTSIVANYFYAENCLVFIEHNH
                     PAGLLIFRLIVLAMVMFGAIGSLPFVWNFADVAMGLMAITNLVAILLLSGLVVKLAKD
                     YNAQRAAGKLPSFDAREYPEIRSRLEPGIWD"
     gene            29059..29919
                     /locus_tag="P5537_03895"
     CDS             29059..29919
                     /locus_tag="P5537_03895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused MFS/spermidine synthase"
                     /protein_id="HRV77218.1"
                     /translation="MHSLLEFPSPFPAEPGLVRLLEPPGSDPAALAARLVAGDYGKPF
                     VLENGGLRALHFSLGYVQSVMDIANPAALVLAYARAMMAFLLFNPRPRRIGMIGLGGG
                     SLANFCHRHLPAAELTVVEIDADVIALRRHFGVPADDARFRVLHADGVRWLGETETRS
                     DVLLIDAFGAEGVAETLLDTDFHANAFRHLGGRGVLVMNLAGTRESFAPHVARLLEVF
                     DERVIAMPVREDGNHILLAFRDPAFAPRWNWMRSQALALQARTGLDFPNLAGALEAGE
                     RQGHAWRLAR"
     gene            complement(29950..30225)
                     /locus_tag="P5537_03900"
     CDS             complement(29950..30225)
                     /locus_tag="P5537_03900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004311276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77219.1"
                     /translation="MKSHLAENVQIAHPRYHLSSDDGLYRPIPFLFVSPRMRDDILDE
                     REMLLSAQAATLHERQHKLFSSYDPALSAEAFRQLLRLYGYPFNNRR"
     gene            complement(30389..30664)
                     /locus_tag="P5537_03905"
     CDS             complement(30389..30664)
                     /locus_tag="P5537_03905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004311278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77220.1"
                     /translation="MKSHLAEDIRIARPRFHLQTRDGLYAPIAFLFVTERMRDDILHE
                     RELLVATLPPAQRARQQKLFERYDPVAGARGFTELLELYRYPFAGSH"
     gene            complement(30820..31368)
                     /locus_tag="P5537_03910"
     CDS             complement(30820..31368)
                     /locus_tag="P5537_03910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004311279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3617 domain-containing protein"
                     /protein_id="HRV77221.1"
                     /translation="MTPLRATALALALACTAQAAHALDNLRPGLWEFRSTRLSVAGLP
                     DMSAQMGMLQQHIKGLPADTRRMLEQQMQQRGVSLGADGSVRSCITPEQARQDNIFAG
                     KVEGNCTLTRVERSGNTIRGSLSCTDPAAEGDFHARVEGPEHFVTRVRLASVRGDLDL
                     ETDARWLAASCGSAGAAAKPAR"
     gene            complement(31523..32602)
                     /locus_tag="P5537_03915"
     CDS             complement(31523..32602)
                     /locus_tag="P5537_03915"
                     /EC_number="3.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016799 - hydrolase activity, hydrolyzing
                     N-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HRV77222.1"
                     /translation="MTPIDREVVIDRAAGALMGAFIGDALALGPHWYYDLDELRARYG
                     SWISDYTAPMPDHYHAGMKAGESSQAGILLRLTLESLADCGGYDEADFCRRLDEELFP
                     QLDGRPMQGPGGYTSQSIREAWRKRVQQRLPWGQVGGNADTTEAAERTLAIAVRYALD
                     PAALADAVTRNTVLTQTDGTVVAMTVAFGAVLGMLVEGHRLDAAISAKLMARVKSGAL
                     PFHTVTVGNLQAPRPGATEAPTAGRFPSPDALLTQSSIARAARDPDVRIEPAWKVSLV
                     YGMPCAVYHQFPAAYYLAARFADDFESAVLHAVNGGGQNLARAMLTGALVGAQVGLKG
                     IPRRFVDGLADHAALLALAGRVAPR"
     gene            complement(32599..34713)
                     /gene="ovoA"
                     /locus_tag="P5537_03920"
     CDS             complement(32599..34713)
                     /gene="ovoA"
                     /locus_tag="P5537_03920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-histidylcysteine sulfoxide synthase"
                     /protein_id="HRV77223.1"
                     /translation="MSLFPRTPLLAGSDVEAKRAELLQYFHATFDRYESLFEVLACDE
                     AYYKKSISLRHPLIFYFGHTATFFINKFMLAGLIEQRIDPRLESMFAVGVDEMSWDDL
                     DDARYDWPTVAEVADYRNKVRAVVDRVICETPFTLPIGWKDPFWAVVMGIEHERIHLE
                     TSSVLMRQHALQYVKPHPAWPPCTEYGEPPANALVDIPAGVVQLGRSFDEPIYGWDNE
                     YGTHRAEVPAFQAARYLVTNREYLGFVEAGGYADDALWDEEGLGWKRYARAEHPTFWV
                     PDTAGWKLRLMTEEVPMRWDWPVEVNCLEARAFCRWKARETGQPVRLPTEDEWNRIYD
                     HVGLADVPHDAPAKANLHLDHWASSCPVTRFAHGELFDVVGNVWQWCETPTYPFDGFD
                     VHPIYDDFTTPTFDDRHGIIKGGSWISAGNESRHASRYAFRRHFFQHAGLRYIVSEAP
                     VLNPASTYETDALLSQYAEFHYGDEAFGVPNFPKALADIAISAQRRFGNGQFGRALDL
                     GCATGRASFELARAFERVVGIDFSARFIQAGVKLAETGVLRYTMPDEGELVTYHERRL
                     DALGLAETAGRVEFWQGDACNLKDVFTGFDLILAANLIDRLYSPRRFLADVTRRLNPG
                     GLLLLASPYTWLEEHTKREEWIGGFKKDGESYTTLDGLKDLLAADFELVQGPQAVPFV
                     IRETRRKHQHTLSELTIWRKRA"
     gene            35390..36718
                     /locus_tag="P5537_03925"
     CDS             35390..36718
                     /locus_tag="P5537_03925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HRV77224.1"
                     /translation="MSSQFRLLRERRFLPFFLTQFLGAFNDNVYKNALMVLITFQAAR
                     LGADSPGVLVNLAAGVFILPFFLFSATAGQLADKYEKSRLIRATKLLEIAVMALAAVG
                     FARMSLPLLLVVLFLMGMQSALFGPVKYAIIPQQLADDELVGGNALVEAATFVAILAG
                     TIVGGLLVMGEAGPGRVAVAVLGIALLGWWSSRAIPPAAAADPGLRVNWNPVTQTREM
                     LRFMLEARTVFAAIVGISWFWFYGALFLSQFPGFAADHLGGDERAVTLLLALFSIGIG
                     AGSLLCGRLSRGRVEPRMVLPGAIGLSLFALDLWWASPAAGAFAPGQELAALFSRAEV
                     WRVVFDLVMIGACGGFFIVPLYALVQQRSAPAHRARVIAGNNILNALFMVGAAAMGAG
                     LLAARLAVPQLFLVTAVLNAVAAAGLFASEPAFRRRSAAPTSHPGPRRLP"
     gene            36939..37685
                     /locus_tag="P5537_03930"
     CDS             36939..37685
                     /locus_tag="P5537_03930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HRV77225.1"
                     /translation="MNPLLALLLALASFTACAQSLPRGDCAAPAAAHDLNGCDFSGRD
                     LTGIDLRGAVLDNASFAGARLDGARFDQASARWVNFRNAQLKAAQFPDADLFHAKFDG
                     ADLSDANLQRSYLFGSNLIGTRAPRADFSGAHLKDLLMPDADLEGARLRDCFALRAVL
                     GGSRMAGADLSGSDFTGAEAEDVDFSGATLRGTRLAGASLAGAVFREAELERADFTHA
                     DVARSDFSRARNLPAQVTELFIAPQMGMAR"
     gene            37765..37944
                     /locus_tag="P5537_03935"
     CDS             37765..37944
                     /locus_tag="P5537_03935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77226.1"
                     /translation="MNLPARLRLAHRRASLRAGVRVRARGIVSPLRDLATQLAFKVTG
                     SPAVLSQAVRGYHRG"
     gene            38183..39055
                     /locus_tag="P5537_03940"
     CDS             38183..39055
                     /locus_tag="P5537_03940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77227.1"
                     /translation="MVLTRSFVRAKRPCTDGFRWFVRQFGEGGDYQAMLDGMVAAGRI
                     GDACWLLEQFGPTDELRVVDAIEADAIVFAGTLEVRGGVDVEGVLRVGRSLQAGAGVR
                     AGGDVRVGTDLRVEGSVRVEGDLQVGGDLRVGWGVDCAGELRCDGELRTGWDLRCGGR
                     LRVAGNAYVGLDLQADEGVRCAKGLQAGGDIQVENTLRAAQGITAGGSIRAGMHLEAG
                     WGIKAGGVIAAAGAIRAGESLAAGEAIRAGAGYGVFAGLDVQMEAWEASARVSAPQRP
                     EGLMSGWWAGPAAC"
     gene            39070..39882
                     /locus_tag="P5537_03945"
     CDS             39070..39882
                     /locus_tag="P5537_03945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77228.1"
                     /translation="MNTLALRPRGLLARNTPLSHRSSFSPRAALAFPQPPPLAAARAA
                     AVRAALGNAFTAVLRRVLQPSRMELRIDVNQPDDSIEAELGILHGRLHRPCDALHACT
                     RLPALLPGLVFHHREADGEHYVYVEDAAHGRLAGYTVFNRLIEVDRRTDRHVRSPHSK
                     YAPAYQGRGIASAVYAWALGRGLCLVSGARQSAGAHALWHALARRHPLRWVALRAKRM
                     HDLGASVPSAQAAELDTRMILLGHGWSAARLRSLGLLHPAAEAANEKMRRRA"
     gene            40225..40986
                     /locus_tag="P5537_03950"
     CDS             40225..40986
                     /locus_tag="P5537_03950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HRV77229.1"
                     /translation="MKLPTAAALFLATSAALTASTAFAQDLPKGDCAAPAPRQDLSGC
                     DFSGRDLAGRDFSGTVLENARFNGARLEGARFEKAMAKWTNFTGARLEGARFAGANLF
                     HARFDGADLSDADLQGANLFGAFLIGTRAPRANLDGAFMKDTHMPEADLSGARLRKVY
                     GLRFILDGSKLAGADLSEADLTGANLEAVDFTAARLAGTRLSGAVLPEAKFADADLSG
                     ADFTHVDVEESDFRGARNIPAALQAQLDKAGQGKR"
     gene            complement(41210..42115)
                     /locus_tag="P5537_03955"
     CDS             complement(41210..42115)
                     /locus_tag="P5537_03955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HRV77230.1"
                     /translation="MDRLQAMRLFTRIVELGSFSRAAEQLGLPRASATQIIQQLEAHL
                     GVRLLARTTRQVTPTVDGTGYYRRCLRILADLDDAEAEFSQAAHHPQGRIRIDLPDSF
                     CRLLLIPALPDFYARYPLVRIEISVGDRQIDLIREGVDCVLRIGELGDLPLHARRLGR
                     LRQVTCASAGYLAEHPAPATLDELEAHWMVDYVSASTAKSLPLEFEVEGRIELRSLRS
                     RLGVNNGGAYVAACAAGFGIVQVPDYHVREPLAQGRFVEILPGFPPPGLPVHALYPAD
                     RPLSARVRVFIDWLAERFGGATAGD"
     gene            42232..43470
                     /locus_tag="P5537_03960"
     CDS             42232..43470
                     /locus_tag="P5537_03960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042925 - benzoate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0042919 - benzoate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate/H(+) symporter BenE family transporter"
                     /protein_id="HRV77231.1"
                     /translation="MLAHLERPAGPAPGLRRILDDFGLTYFANGLIGFIFSATGPVAI
                     ILSVGTRGGLSEAELASWVFGVFFINGLITLAMSWRYHMPLGFAWTIPGTVLVGPALQ
                     HLSFAEVIGAFYATSLLVVVLGASGWVRRVMSALPMPIVMGMVAGVFLRFGLDIVRAL
                     DSDVAIAAPMVAAFLLLSASPALGRRMPPVIGALLVGALAIALLGRIDGGALGGFAFA
                     QPLVQAPVWSVAALVELVVPLAITVLVVQNGQGVAVLKNARHDAPVNTVAFVSGIGAF
                     FSAMVGAVSSCLTGPTNALLTSSGEHGRQYTAALTFGLFGVLFGLMAPTFTGLMLAAP
                     KEYIMVLGGLAMLRVLQGAFVASFGGGRFTLGALVSLLVTVADIGMFNIGAAFWGLVA
                     GFGVSWLMEKQDFTALANRT"
     gene            43550..44932
                     /locus_tag="P5537_03965"
     CDS             43550..44932
                     /locus_tag="P5537_03965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HRV77232.1"
                     /translation="MSPSSLAPSGTRAIVGQLLHLAWPILIAQLLSMTMMVADTVIAG
                     RYGTEDLAGVAIGSSYYISVVMLLTGTLQAISPTIAHHVGAGREEAIAPALQQGFWLA
                     LLLTGPGIALLLNPGFLLEAASVPPAVAAKAADYLAATAFGLPALLLYRSFYAFNNAV
                     GRPRVLMAISAITMSTHIPLAWALTNGALGFAPMGGTGCGVSTATVHWIALGCGLAYL
                     VFNPAYKPYRLFHAWQAPRAQALGQLLRLGLPMGVSTFIDISSFTLIAILAARLGTET
                     VAGHRVIANFTGMIYMLPLSLSIATMVLVGQSAGAQDWRRARRTARLGMNLALGFSLL
                     VGALLWVLREPLVAFSSADPAVQAVALGLVVWLLLYQCFDALQTVAAHALRGYKVTLL
                     PMLVHTFCFWGIGLAGGYWLSFHAPWRTEAPTVAGFWEACVLATLAATLLFGALLRAV
                     SRRHVREAAV"
     gene            45377..46024
                     /gene="pdxH"
                     /locus_tag="P5537_03970"
     CDS             45377..46024
                     /gene="pdxH"
                     /locus_tag="P5537_03970"
                     /EC_number="1.4.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004733 - pyridoxamine-phosphate oxidase
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase"
                     /protein_id="HRV77233.1"
                     /translation="MSKNAPLSDLRKSYEQGTLEEHDSANEPLQQFETWLSQALERGL
                     PEPNAMTVATVGEDGRPSTRPVLIKGCDARGIVWYSNYHSRKGRELEARPFAALQFHW
                     VEMERVVRIEGRVEKVAAEESDAYFATRPLAHRIGAWASPQSEVIDGRTTIVSRAAEY
                     GLKFGLNPPRPPHWGGYRLLPDYWEFWQGRTSRLHDRIAYRLQPDGSWARQRLAP"
     gene            complement(46592..47251)
                     /locus_tag="P5537_03975"
     CDS             complement(46592..47251)
                     /locus_tag="P5537_03975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LUD domain-containing protein"
                     /protein_id="HRV77234.1"
                     /translation="MSAREAILNAVRGGLGHRTVDPAALRREADALLEDLPAIRPGLL
                     ADDLVEAFIARLVTPKVAATAERIADASALPAAVARYVEARGLPAAIALQPAAVLQAL
                     DWAGFELHERVAPDETLAVGFARWGIAETGSLVFHSDAETPILANFLPLHHLVMVRAS
                     TVLAYLDDYAAATAGQRPPRNVNIITGASGTTDIEGSLVLGAHGPRYLHVVIVEDAPA
                     A"
     gene            complement(47248..48657)
                     /locus_tag="P5537_03980"
     CDS             complement(47248..48657)
                     /locus_tag="P5537_03980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0019516 - lactate oxidation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LutB/LldF family L-lactate oxidation iron-sulfur
                     protein"
                     /protein_id="HRV77235.1"
                     /translation="MEEATLSFKARAERALADPTLKIAIDRTTGTAERKRAVAMSQFP
                     QFEAARERGKRIKDHVIANLDHYLLEFERNAIASGAKVYWAATAEEAAQIVVRLCKEA
                     GAKRVTRVKSMLGEEIGLPHALDEAGIERVETDLAEHIVQLGGDRPSHIVWPSMHRTR
                     EQVSEMFKRLHRAPHQEETIEAMVDSARRELRDKFLTADVSISGANFLLADTGATCTV
                     TNEGNAELTTTPPRVHIVTAGIEKLVPSMGHAIAMLRLLVRSATGADVTQYTTFHCGP
                     KQAGDRDGPEEFHIVLVDNGRSRMLREGMKEMLRCIRCGACMNHCVVFRQLGGHVYGG
                     TYPGPMGAVLTPVFDGLEKSRDLPHACTMNGKCQEVCPVAIPLPTLLRGWRDRSWREG
                     LEPSVVRFGLGIHTFVASHPRLYRLGTAIAVRVMRLFSRGGLVKGMPGLGAWTAHREF
                     PAPAKRTFMEMVKDQENAR"
     gene            complement(48661..49446)
                     /locus_tag="P5537_03985"
     CDS             complement(48661..49446)
                     /locus_tag="P5537_03985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(Fe-S)-binding protein"
                     /protein_id="HRV77236.1"
                     /translation="MNEPRSVSRPVSPRVALFATCLVDAMRPSIGFAALKLLRDAGCR
                     VEVPQAQTCCGQPAFNSGDIAHAATLARHFIQTFEGYDYVVAPSGSCIGMTRVHYAEA
                     LADDPAWAERARRLGERSFELMSFLVDVMGYAPTDVRLDTSFTYHDSCSGLRELGVHD
                     QPRALLGKVAGLTLKPLEGNDVCCGFGGTFCVKYAAISNAVVGEKAEAIERSGAQLLL
                     GGDLGCLMNMAGKLKRKGSGVRAFHAAEVLAGMGGGPAIGEEG"
     gene            49756..>50023
                     /gene="fdhE"
                     /locus_tag="P5537_03990"
     CDS             49756..>50023
                     /gene="fdhE"
                     /locus_tag="P5537_03990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory protein FdhE"
                     /protein_id="HRV77237.1"
                     /translation="MNTQAIQLPPSGEAAAILLPDPATVFLARAERFDALALHHGLGE
                     WLAFLGRLSRAQHAALQAAAPDIAPPAEDVLARARKHRMPPISVA"
BASE COUNT         7012 a        18196 c        17758 g         7057 t
ORIGIN      
        1 gatggaggca accatctgtc cgggagaatc gatcgacagc gggcgctcga ccgagatcag
       61 cacgtcgtcg gctggcgaca ggttggcggt gccaccccag gccaggcagc cgcggtgctc
      121 gcgcacgatg cccgagagca cctcggtggg cagctcgacg caggcaagga cctccatggt
      181 gtcggccgta cccgccggcg aggtgatcgc gcgcgaggag gtcttggggc acagcatgcc
      241 gtgcgcggcg acgatcggca ccaccagcat cgaggtgcgg ttgccgggga tgccgccgat
      301 gcaatgcttg tccaccaccg ggtgctcacg ccagtcgatg cggtcgccca ccgccgccat
      361 cgcctcggtg aggaaagcca cctcctcgcg gtcgagctcg ccctggttgg tggcgaccac
      421 gaaggcggtg agctcgatct tggaatagcg gtgctcggcg atgtcgcgga cgatggcgcg
      481 gaaatcgtcg cgagcgagcc gctcgccggc gatcttgcgg cgcagcgccg ggatcgagga
      541 cggcggctcg gcctgcgcga tcatcgccgg gtggccgtcg tcgacaccga gctggatgaa
      601 ggcatcgatc gacaccccga gctcgtcggg ctggacgatg cagccgtcgt cgacgacgtt
      661 gaggctggcg aggatgcggc ggccattggc acgcacctcc accttggaga gagcctggaa
      721 gccctcggca cgatagatcg cgcaatcgcg atgaaggtac acgacgttct cgcgccacgt
      781 atcgatcgcc accctgcgca ggcgcaaggg agaggccgac tcggccgcga cggcagggat
      841 tccggcttgt gcgtccatga gttgaatcta gaccgtcgcg gacgcgggag aaaggacgga
      901 gttcacgtgt cacgcctgcc tgcagggcga ggctcctgcg agagtgggtt cgagcgagct
      961 cggcgcaggg ccgcactgcc gactcgagcc aatcacagac ctccagaagc ttaagcaatg
     1021 tcaagacctc gccgcctgat tcgtcatatg gtgtgacaaa agtcacgcca acgaaaaaat
     1081 aggaggccgc catgaccaac cgcaacatct ccttcatcgt caaggaccag aacccgctga
     1141 tgctgcgccc ctccgacacc gttcaggccg cctgccgcag catgtgcgag cgcagcgtgg
     1201 gcgcggtgct ggtgaccgac gcgcgcgccc atctcaaggg catcttcacc ggccgcgacg
     1261 cggtgcaggt gatcgccaac ggcggcgatc cggccaaggt ccatctgtcc gaggtcatga
     1321 cggcgaagcc cgacaccatc gagcccgagc gcaaggcgat cgacgcgctg cacatgatgt
     1381 gcgacggcgg ctaccgccac ctgccggtgg tggtcgatgg caaggtcgtc ggcatcgtct
     1441 cgcgcagcga cttcaagggc ctcgaactcg accagttcga agacgagcag agcctctggg
     1501 agcgcatctg ctgacaaccg aggcacgcgc tacgctgcga ggcccgcaca gcgcccggag
     1561 gtgcatgcgg gtcctttgtt ttcactccac cccgaagcgc aacgtgccga tcatgcggtc
     1621 gtcggcggcg agcacctgca cctgccagcg cccgcgcgga tcctccggga agttgcgctt
     1681 gcgcgtccat gcccggtagc cctcggcgcg gccgccgctc acctcgagtt cgatgcggtc
     1741 caccacctgc ccctcgtggc gccacacatg gacgaccttc tcggaaagtc ccagcggcgc
     1801 atggatcgcg gtgtaggcat agagtccctc ggcgagcaga cggcccgcct cgatgctgcg
     1861 caggctctcg gcgggcgcac gctgcgcctc gtccaccacg ctggtcaccg cgacctgggt
     1921 caggcgcagc gtggccggcg gtacccacag ccgcgccagc cagcccgccg cgccaagcgc
     1981 ggcgagcagc gccagcacca gcaggccgcg ccaccagcgc ggcacgctga tcgccccggc
     2041 gagcgtcgga aaggacagca ccacggccac cgcaagcgcg agctggtagc tcgccatcgc
     2101 cggcacctgc agtaccagcg ggaacaacac gagcagcagc gcgaacaggg tcagcgtgtg
     2161 gtagccgagg aagagccagc gccgcgtggc caggcggccg aagtagaccg ggtcgaggat
     2221 ggcgaccagc gccatcagcc cgagcgcgcc ggtaaacacc gcctgcccgc tgttccacga
     2281 cgtgctggcg aagaagaaag gcagcgcgaa gaacaggctc tcctggtggg tgaactgggt
     2341 caggtagcgc accagcaccg gtggcaggcc gaagccgaag cggcgcttca ccgcgcggtc
     2401 gagcacgcgc tcgagcacca gcaacaacca gccggccagc atcgccaccg ccatcgcgcg
     2461 cgccacaccc tcgtggcgct cgaccaggaa gaagctcagc accccggaga cgaagccgaa
     2521 ggtggcgatc agccagggat ggcggcgcag ccacaccacg aggcgcaggc caccctcctt
     2581 caggcgggcg aggcggctgc cgctcgtggc ggagtcggtc tcctgcaacg aggcgaccag
     2641 ggactcggtg gatgggtagg actcgtcctt catcgtccga ggtcgcgcag gtcggccacc
     2701 ggctcgcggc cgaagtcctc gtcgagcacg aagtcgacca ggtgcatcgc gcactcggca
     2761 ggggcgacca ggccgccgct cgcctgcatc tcggcgaagc ggtcgcgcag cgggaagcgc
     2821 tccggcgtgc tggcgcggat ctcggcctgc atgccggtgt cgatcacgcc cggcgcgagc
     2881 gcgcagatac gcagcccggg cacggcgtcg agctgcaccg cgcgggcgtg gtggtcgagc
     2941 gcggccttgg tggcgcaata cacgctccag cccgcgtagg gcttgcgcgc ggcgccgctg
     3001 gagacatgca gcacgcggcg cgcctgcggc ccggcggcgg ccgcgaaggc cgcggccagc
     3061 gccagcggcg caccgacgtt ggcagccacg gcgcgcgcca ccgccatggg gtcctgcagc
     3121 gccagcggtc ccatcggctg cagggtgccg gcgttgttga tcagcagcgc ctcgtcggcc
     3181 tcggcgagcc aggcctgcag cgcacccgag ccgagccagg cggcgagcgc cgcgctgtcg
     3241 gcgaggtcga ccgcgacctc gcacaggcgc tcgccatgac gggcggcgag cgccgggttg
     3301 ccgcggcgcg cgagcgcgag caccgcgatg ccgcgatcga ggagctcctc ggcgatcgcc
     3361 tcgccgaggc cgcggctgtg accggtgagg acggcacgca tgcccctcat cgcccaggct
     3421 ccgccgcagc atcggccgga cggcgcgcga ccaggccgac cagggccgag cgccccttgt
     3481 ggccgacgcc ctcctccagc acgtcctcgt actcctgcag gtgcacgatc tccagcccgg
     3541 cgaaggcctc gcgcagcagc tcggcggtgt ataggttctc caccgccgat ggcccgccgg
     3601 tgcggtattc gagctgcttc ggggtgtagc cctgcaggat cagatggccg ccaggcctca
     3661 acgcgcgtgc catgccggcg aagatgtgcg cgcgctgcgc cgagtcggcg aactggatga
     3721 agatcgccac gacgaagtcg aaggcggcct ccggatagtc ccacgccacg gcgtcggcga
     3781 gcacgaagtc gacctcgacg tggcggccag cggcgagctt gcgcgctttc tccagcgcca
     3841 ccggcgagat ctcggtggcg gtcaccgcga gcccctgctc ggccagccac accgcgttgc
     3901 gcccctcgcc gtcggccacc gagagcgcat cggcgccaga ggcgagcagc gccgcctgcg
     3961 cggcgaggaa gcggttgggg gtggtgccga agacgtagtc ctcgcccgcg ctgcgatagc
     4021 gcgtggacca catgtgttcc tgttcgtgtg cgttcatcgg tgttcctgga aagagccgcg
     4081 gcggcgggcc gcggcaatca ccacggcacg ggctcgccgc ggtggtcgaa gaattcgccc
     4141 gagtcgttcg gcccgaggcg cccgatcacc gcgagcaggc gcgcggccgc ctcggcgggg
     4201 gcctgcacct gcagcccgga cttggcgaag ggcgccgaca ggccggtgtc gaccgtcccc
     4261 ggatgcagcg ccacgcagat cgcctgcggc cggctgcggc gcagctcgac cgcggcggtg
     4321 cgcacgagct ggttgagcgc cgccttcgag gcgcggtagg cgtaccagcc gccgaggcgg
     4381 ttgtcgccga tgctgcccac acgcgccgac agcgtggcga acaccgcgcg gcgctcgcgc
     4441 ggcagcagcg gcaggaaatg cttcatcagc agcgctggcc cgatcgcgtt gatcgcgaag
     4501 gcgtgcgcca gatgggcggg atcgagctcg cgccagctct tctccggctc catgcccccg
     4561 ccgtggagga agccggtggc gtcgaagacc agggtgggca cgccgcgcgc gcgcaccgcg
     4621 gcggcggccg cggcgatcga ggcctcgtcg agcaggtcga gcgccgggct gccccggcgg
     4681 ccgagcgcga gcacctcgtc gtagtctccc gcctcgcgca gcgcggcgac gacagccgca
     4741 cccacgccgc cgccgctgcc cacgaccacg gcgagcgacc tgccatcggc atcctgcgct
     4801 cgccccccgg ctcgcgccgc ctcgcctacg ctgctgctca tgatccggcc tccaggttgt
     4861 cgcgcccctc ctccaccgca tggcaggcca cgcgaccgcc gtcgtcgagt tcgcgcaagg
     4921 ccggcacctc ctgccggcag cgcgcgtccg cgagcgggca gcgcgggtgg aaggtgcagc
     4981 cggtgggcgg ggtgatcggg ttgggtacct cgccgcgcac ggcgtcgtcg gcccggccgc
     5041 gacgggagaa gtcggggatg gtcgccagca gcatgcgcgt gtaggggtgg cgcgggcgct
     5101 cgaacagcct gcggctggtg gcgatctcga cgatgcggcc gaggtacatc acgccgatct
     5161 cgtcggccat gtggcgcacc accgcgaggt cgtggctgat gaacaggaag gtgagcccga
     5221 gcgcgtcctg caggtcgcgc atcaggttga ggatctgcgc ctgcaccgac acgtcgagcg
     5281 ccgaggtcgg ctcgtcgcag acgaggaact cgggccggtt ggcgagcgcg cgcgcgatgc
     5341 agatgcgctg gcgctggccg ccggagaact cgtgcggata cttcgcgccg tcggccggcg
     5401 acaggccgac ctggcccagc agtccggcga cgcgcgcgcg gatcgccgcg tcgtccttct
     5461 ccagaccgaa cacgcggatc ggctcggcga tgatgcgctc cacgcgccag cgcgggttga
     5521 ggctggcgta ggggtcctgg aagatcatct gggagcggcg gcgcagcttc tggcgctcgg
     5581 cactgccgcg cacctcggcg aggtcgcggc cgtcgaacac gacgcgcccg gccgagggct
     5641 cgtgcaggcc cacgatcagg cgcgccacgg tggattttcc gcagcccgac tcgcccacca
     5701 gcgcgaaggt gcggccgcgc gggatcgcga acgagacccc atcgaccgcg cgcagccagc
     5761 gccgcggctc gcgcgcgagc aggcgctcga gccacggcct ggagacatcg aaggcgcagc
     5821 gcaggtcctc gacgcgaagc agcggcgccg cggcgcccgg gtcgcgcacc cggcgcgctg
     5881 cggccgcggc cggcgctgcc ggcgcagacg ccatcgcgtc ctccgcaccg gtcggcgcca
     5941 gcccgggcgc gggcagctgc gccggcgcaa gctccctgcc ttgcggctcg cccgccgggc
     6001 cggcatcgcg cggggtctcg tcccgcgcgc cgggcgcggt cgcggtcgcg gtcgccggca
     6061 gcgcggtccc ttcgccgacg tccggcgcat cgcccgggcc acgcgcggga ccgacgtccg
     6121 cgcctgggtc ggcctgtgcc cggtgcacca gcccctcggc gtcctcgacc gcggcgcggt
     6181 cctgttgctt cgccttggcg agcgcccgct cgatgatgct catcgccccc ctccttcagc
     6241 catctccgcc ggcgcgtaca gccagcacgc cgcgcgcgtg gcgcccgccg gctgcagctc
     6301 ggggcactcg atgcggcagc gcgcgaaggc cgcggcgcag cgcggatgga aggcgcagcc
     6361 cggcgggatc gcgtccaggc gcggcatcgc gccgtcgatc tgcaccaggc gctcgacctc
     6421 gtcaccgagc accgggatgg cgcccatcag gccgcgggtg tagggatgcg ccggcgcgca
     6481 caccacctcg tccaccggcc cgatctccac cacccggccg gcgtacatca ccgcgacgcg
     6541 gtcggcggtc tcggcgatca cgcccatgtc gtgcgtgacc agcatcaccg cggtgtggtg
     6601 ctggcggcac aatcggcgca gcagcgcgat gatctgcgcc tgcaccgaaa cgtcgagcgc
     6661 ggtggtgggc tcgtcggcga tgatcagctc gggctcggca cagagcgcga gcgcgatcac
     6721 cacgcgctga cgcatgccgc cggaaaactg gtggggatag tggtcgatgc gctgcgccgg
     6781 cgccgggatg ccgacctcgt cgaggagtgc gagcgcgcgc tcgcgggcgg cggcgggggt
     6841 gagctcgagg tgggtcagca tggtctcgac cagctgctcg cccaccgtgt acagcgggtt
     6901 caggctggtg agcgggtcct ggaagatcat cgcgatacgg cgcccgcgca ggcgccgcat
     6961 ggcttcgccg ctcagctcgt ggatggcctc gccgtcgagc aggatctcgc cgccggcgat
     7021 gcgcccgggc ggctccagca ggccgatgat ggccgcgccg gtgagcgact tgcccgcgcc
     7081 cgactcgccc accacgccga gcacctcgcc gcgcgcgatg tcgaaggaga cgtcgtcgag
     7141 cgccagcagg gtgccgcgcc gcgaggggaa ctccacccgc aggcggcgca ccgacagcag
     7201 cggcaggccg ccaccggcgt tcatctggtc gatgtgcggc acgttcatcg gcgcagcctc
     7261 gggttgagcg cgtcgcgcag ccagtcgccg agcaggttca ccgacagcgc gagcagcagc
     7321 agggtgaggc cggggaagag cacgatccac cactcgcccg agaacaggta gtcctggccg
     7381 acgcggatca gcgtgccgag gctgggctgg gtgggcggta cgccgacgcc caggaaggac
     7441 agcgtcgact ccaggatgat cgccagcgcc aggccgatgg tggcgatcac cagcaccggc
     7501 cccatcacgt tgggcaggat gtggcgcagc aggatggtgg gcgccggcac gccgatcacg
     7561 cgcgcggcct gcacgtactc cttgttgcgc tcggccagcg tggaactgcg caccgtgcgc
     7621 gcgtactgca cccagtccga aaggccgatc gccaggatca gcacgtagat cgccgccttg
     7681 tcgtgcagcg ccggcggcac cacgcccttg aacacgccga agatcagcag cgccaccagg
     7741 atcgccggga agctcagctg cacgtcggcg acacgcatga tcaggctgtc cacccagccg
     7801 ccgcggtagc cggcgacgag cccgagcgtg atgcccagca ccgcggcgaa ggccaccgcc
     7861 gcgaagccca ccaggatcga cacccgcgag ccgtagagga tggccgagaa caggtcgcgc
     7921 ccctgcgcgt cggtgcccag ccagtacacg ttgccggtga attcgttggc ctgcatcggc
     7981 cgggtgaagc cgtccatcag gttgagcgtg gcgggatcga aggggttctg cggcgcgatc
     8041 accggcgcga gcagcgcggc gaccaggatc gccagcacga ccagcgccga gagcacggtg
     8101 atcggcgagc ggatgaagct gtggaagagg tcgccgtcga gcaggcgcgc gagcgcaccg
     8161 cgcgggacgg gcggcgcggc ggccggggcg gacgtggggg gttcggtgcg catggcgggc
     8221 tccggggtgc cgggggcgct cactgcccgc gcccgctgcg ctgcacgcgc aggcgcgggt
     8281 cgacgacgaa gtagagcagg tcgacgatca ggttgatgac gacgaagatc agcgcgatca
     8341 gcaccaggta ggccgccatc accgggatgt cgacgaactg caccgcggtg atgaagagca
     8401 ggcccacgcc cggccactgg aacaccgtct cggtgatgat ggcgaatgcg atgatcgagc
     8461 cgatctgaag cccggtgatg gtgatcaccg gcagcagggt gttgcggagt gcatggccga
     8521 aatgcaccgc gcgatcgctg agcccgcggg cgcgcgcgaa cttgatgtag tcggtgcgca
     8581 gcacctcgag catctcggcg cgcaccaggc gcatgatcag cgtgagctgg tacaggccca
     8641 gcgtgatcgc cggcatcacc agcgacttca gcccggaggg ggtcagcagc ccggtggtcc
     8701 accatcccag gtccaccacc tcgccgcggc cgaaggcggg cagcaccttg agttccaccg
     8761 cgaacacgta gatcagcagg atgccgatca ggaaggtggg cagcgacacg cccaccagcg
     8821 acagccccat gatcgcgtgg ctcagccagc cgtcgcggcg cagcgcggtg tacacgccga
     8881 gcgcgatgcc cagcgcgagc gcgccgaaac cagagatcag cgccagctcc agcgtggccg
     8941 gcagacgctc ggcgatcacg tccgccaccg gccgcgccat gcggtaggac acgccgaact
     9001 cgccctgcgc cgcgttggcc acgaagcgca ggaactgcag cggcaccgca tcgttcaagc
     9061 ccagcgattc gcgcagcgcc tcgcgctcgg ccatggtcgc ctcctgcccg accatgttgt
     9121 tcaccgggtc gccgatgtag cggaacaggc cgaacgcgac cagcgccacc gtcagcatga
     9181 cgaggacgga ctgcaacagg cggcgcagga tgaaggcggg catgggatgt gaggcggcgg
     9241 gagcgaggcg tgaggcgcgg gttgggcgcg gccgggtggc cgcgcccgcc cgtcacttcc
     9301 tgtacttcaa cagcttgaag tagggatagt tctccgactg caccgggaag tcgatgtcgt
     9361 ccttcatcgc ccagttcagc atctggtggt ggatcggcag gtagacgatg tcgtcctgca
     9421 ccgtcttcca ggtctccgcg accatgccgg cgcgcttgcc gaggtcgatc tcacggttca
     9481 tcgccttggt cagctcatcg accctggggc tggaatagcc ggtcacgttc cacgagccgc
     9541 ccttgtcggt ccgcgtctcg tacagatagt ggaagacata gtgcgaatcc atggtcggca
     9601 cgccccagcc gagcatgtag aggtcgagct cgcccttggg cagctcggcg aagtggatgc
     9661 tcttgggccg cgcgtccagc cgcgccttga cgccgatctg gccgaacatg ccggttgccg
     9721 cctggcagat cgcctcgtcg ttcacatagc ggtcgttggg gcaggacagc gtgaccgcga
     9781 agccgtcggg gtagccggcc tcggcgagca gcgccttggc gcgcgccacg tcgggcgccg
     9841 gcaccacgtc catcgccttg tcgtagccgt cgatgaaggg cggcgcgacg atgccggcgg
     9901 gcaccgactg gccgcgcatc accacgcgcc tgaccgcctc gcggttgatc gcgatgttca
     9961 tcgcctcgcg cacgcgcttg tcggcgaagg ggttcctgcc cttgacgtcc gagctgcgca
    10021 gctcggtcgc gccctggttc atgccgaaga agatggtgcg gttctcgggg ccggagcgca
    10081 ccacgatgcc cttggccgcc gacaggcgct cgaggtcctg caccggcgga tcgagcagga
    10141 agtcgatctc gcccgagagc agcgccgcga cccgggtggc ggccgagcgc accggggtga
    10201 acacgacctt ggccacctcc atcgggtagc tgcccttgcc ccagtagtcc tcgttgcgct
    10261 cgagctcggt gcgcacgtcg ggctcgcgct tcaccagccg gaagggaccc gtgccgttgg
    10321 tgttgcgcac cgcgtaggtc tcgtcgccgg ccttgtagtt ctgcggcaag gtgaccttgt
    10381 tcgcctcgga ccactcgcgg tccatgatga agaggttggt gaggttgttg ggcagcagcg
    10441 ggttggggcc gtcggtgcgc atgcgcacgg tgtgctcgtc aaccttggtc acttcgacca
    10501 ccgaggtcag caggcccttc atgtccgagt tctcgtgctt ggcgcgcagg atcgagaaca
    10561 ccacgtcgtc ggcggtgaag gggttgccgt tgtggtactt caccccctcg cgcagcttga
    10621 attcccagac gttggggtcg tcggtgatct tccacgaggt cgccagccgc ggcgccagct
    10681 tcatggcctg gtcgcggaac accagcgagt cgtacacctg atggttcatg acgtgggtcg
    10741 gaccctcgtt ctgcgcgtgc gggtccatgg tcagcgcgtc acccgcggcc gcccagcgca
    10801 cggtctgcgc ggaagcgggc gtggcggcca tgccggcgag ggtcgcgagg gcaaagggca
    10861 gggcgagggc gagtcgggtc ttgttcattc ttcgatctcc gtcgggtgct gctggggctg
    10921 aaaggcgggt gggccggcgg gctgccggaa ggcccggcag cgagcatgcc ggccgattgt
    10981 tgcaccggcc gggccggcgg gccaagcgca ccgtctccgg atcagggttc tccccgatcc
    11041 ggggtgcgta cgccctcagc ccagccagcg tccgatcgtc cccatggcga tggtgaggaa
    11101 gccgagcgtc aggttggtac cgacgagctg gcggatgcgc ccgagcgccg cgccgcccgc
    11161 cttccagtcc tcggccacga ccgcgcgcgt gagcgcggcg tagggcgtga agaacacgaa
    11221 ggcgtagatg gcgatcatca ccagccccat caggaacatg atgtgctggt acagcggcgc
    11281 cgccgcgaag ccatagcgca ggatcagcgc cagcccgctc accagcaccg cggcgaccgc
    11341 cacccacacc caggtgaaga agcgcgccag cacaccgcgc cagaggcgca gccgcggcgg
    11401 cggctcgagc tggctggcgg cctcggggcg caggcagacg taggcgaaga acatcccgcc
    11461 cacccagacg acgacaccgg cgacgtgcag gaaaagcagc agcggatgca ggtccatggg
    11521 gattctcctt cgtgggatcg gaagcccgat tgtgccgcaa aagccggcct gcgccggcag
    11581 atcgcgacat gtccggccct catgcgccgg atggcagatg gacgaggtcg gccgggacgt
    11641 cgatgtcgtg cagcgcgggc agctcgcggc aggaccatgc cagcgccgcg atgcgcgccc
    11701 gggtctccgc tgccacggtc ggcgtgctcc aggcgatgcc ctcgaagagc cgcgggtcga
    11761 agcggcgcag gccgagcagc acgtagccgc cgtcgaagct cggcacgatc accgcctcga
    11821 cctcgtcgag cgcctcggcc gcggcgcgca ggcaggcggc atcgagcgcc gggcagtcgg
    11881 tgccgatcag cagcacgcgc tcgccgccgg cgagcacccg gcgcgccgcg cccgccatgc
    11941 gcgcgcccag gtcgccctcg ccctgcgcgg accagcgtag gcccgcgggc accgtgaggc
    12001 cccgccaggc cgggtctccc ggggcggggc tggcgcacag ctccaatccg ccgggcaatg
    12061 cttccgcggc cgccgccagc gtgcgcgcca gcatgcgcgc ggcgagcgcc gccgcaccgt
    12121 cggcgccgag cgcggggatc agccgcgtct tcacccgccc cggctgcggc gccttggcga
    12181 acaccacgat gcgggtcgcg ctcaccggta ggcctcggcg aggcgctcgg ccggcacgcc
    12241 gcgccagtag gcccagcgca gccgccacat cagcgcgatg gtgcgccaca cgccgcgctg
    12301 ctcccagcgc cgccccgagg tccgcacccg cgcgcgcagg caggccgggc gcgacacgcg
    12361 cagcagccgg cacgagagct cgatgtcctc catcaggggc tggtccggga agccgcccac
    12421 cgcctcgaac acgtcccggc gcacgaagat cgcctggtcg ccggtggcga tgccgctcag
    12481 ccgcgagcgc aggttcatca gcgcagccac cacgcgcagc atgcgcgggc ggccgtcgat
    12541 gtgcacgtcg aagcggcccc aggcctggac ggcaagcgcc gcgcacacca tcgcgtccgc
    12601 cgcctcgggc aggcgcgtgt ccgcgtgcag gaacaacatc agggccctgc cgcacgcctg
    12661 cgcgcccgcg ttcatctggc gggcacggcc gcgctcggcg atcagcacgc ggaaacccgc
    12721 cgcgcgggcc atctccaccg agtcgtcgcg gctgccgcca tcgaccagca cgacctcgca
    12781 gccgcgggca cgccagccgg cgaggtggac gagcagcgcg ggcagcgtgg ccgcctcgtc
    12841 cagcatcggc accacgatgg cgagcgcctc cgcgcgctcc tcgacctgcg gcgccgccat
    12901 gctcagccct tcagcgcccc gccgcagctc gacccgctgc ccgccgtgca gccgaagcag
    12961 tggtcggcga cgcggatcga cgcgccagcg aggtcggccg cgagcaggtc gcgcaggtgt
    13021 agcgcgccgg gccgggccgc accggcggcg tcggcatcgc catcgcccgc cggcaggccg
    13081 agctgctggt tgaagtcgca gtcgtacagc cgcccccgcc agtccacgct gacgaggctg
    13141 cggcacatca ccgcggccag gttctcgtcg cggtgggcgg cctgcagcag ttccatgtag
    13201 gcgttgaact gtcccttcga gatcagcatc gagccgaagc gctggatcgg catgttggcg
    13261 agcgcgaaca gctggttgaa gacgatgccg aagtgcgccg cgagttcgcg ccggtaatcg
    13321 gcctcgagcc gggcctggtc gggcggcagc accggaccct gcgggttgta caccaggttc
    13381 agcacccgcc cgctgccggg ctggccgtag ccgagcgcgt taaggtgcag cagtccggcg
    13441 atgctgcgct cgaacacgcc cttgccgcgc tggcggtcga cgttgtccgc cgagtagcag
    13501 ggcagcgagg ccacgacctc gacatcctgc ccggcgagga actcggccag atcctcctgc
    13561 cccggctcgg acaggatggt gaggttgcag cggtcgatca cacgcacccc gagcgcccgt
    13621 gcctcccgca ccagggcgcg gaagcccggg tgcagctcgg gggcgccgcc ggtgaggtcg
    13681 agcgtgccga tcgcgcgcgc ggcgagcacc tgcgggatca gcgccatcgt gtcggcgtcc
    13741 atcatctcgc tgcggttggg gccggcgttg acgtggcaat gcacgcagct ctggttgcag
    13801 cgatagccca ggttaacctg caacgtggtc gtcgcctcgc ggcgcagcgc cggaaagcgg
    13861 cgcgattcga gcagcgggag ggtggcatgc atgcggagag tctccatcgg gaaatcgatt
    13921 cttgcagcgg ctgcggaatc cgcagcggcc ggtacggtct tctgtcgtac ctgtctcgga
    13981 aaaccttacg ctcgggaagt tcgatcccgt cgcatcatcc tgcatcccat cctgcccctc
    14041 ccccggcctc ctgcccattc gaccccatga agcgactcct cctcgtcggc ggcggccacg
    14101 cccagctcgc ggtcctgcag gccctcgccc gccaacgccc gcgcgcggtg gaggcggtgc
    14161 tgctgacgcc ctcgccctgg caatggtact cggggatgct ccccggctgg atggccggcc
    14221 actaccgcgc cgaggattgc cgcatcgacc tgcgcccgct cgccgccgca gccggtgtac
    14281 ggctctgtct cgccgccgcg gtggcgctcg acgccgaccg gcgcaggctg caggacgact
    14341 cgggcgcgat tcacgacttc gacctgctgt cgctcgacgt cggcagcctc accgacacgc
    14401 acgcgctcga ggccctgccg gcgggcaccc tgctgccggt aaagccgctg caggccttct
    14461 tcgccgcctg gccgcagcgg ctcgccgcgg cacgcgccgg ccaactgcac cggctcgcgg
    14521 tcgtgggcgg cggtgcggcg ggggtggagc tggtactcgc agccgcgcag gcctttcgcg
    14581 gcgccagctg cacggtggcg ctcgcgctcg tggcgcctcc tggcggactg ctcgccggcc
    14641 atgccgaggg cgtgcgccgg cgcgtcgagc gtcggctggc gcaggcgggc atcgcgctcc
    14701 acctggctcg cgccgggggc actgcggcag ggctggtgct cgaccacggc gcgggggacg
    14761 cccccgccgc cctgcccgca gactgcgtga tcgccgccac cggcgcgcgc gccctgccct
    14821 ggttgcgcga gagcggcctg gcctgcgatg cggacggctg ggtcgccgtc gacgcgggtc
    14881 atcgcagcct ctcgcacccg gccatccacg ccgccggcga cgtgtgcacc cgcgccgtgc
    14941 ccggcttcgc gcgctcgggc gtgcatgcgg tgcatgcagg cccagtgctc gccgccaacc
    15001 tgctcgccgc cctggagagc ggcccggcga gcacgccgcc acacacctac cggccacgcc
    15061 cgcgttcgct ctacctgatc gcgagcggcc cgcgccacgc gatcgcgtcg tgggggtgct
    15121 ggtcggccga gggccgctgg gtctggcact ggaaagccta cctggaccgc ggcttcatcg
    15181 cgcgccaccg gcgcgcagcc atcgtgccgg tgtaagaatc cgcgaagccc atgcgacaaa
    15241 gcccgaaacc ctgtccttct catcccccct tttcccggag ccccgccatg cacgaactcg
    15301 tccaggacta ctacggccgc accctgcagt cctccgctga cctaaagacc tcggcctgct
    15361 gcgacgccag cgcgctgccg gcggcgctca agcccgtgct cggccgcatc caccccgagg
    15421 tgctggcgcg ctactacggc tgcggcctgg tgagcccgcc cctgctcgag ggctgccgcg
    15481 tgctcgacct cggctgcggc tcggggcgcg acgtgtatgc gctcgcgcag ctcgtcggcg
    15541 agcgtggcga ggtggtgggc gtagacatga cccccgagca gctcgcggtc gcgcgccgcc
    15601 acgaggacta ccaccgcgag gccttcggct tcgcgcgcag caacgtgcgc ttcctcgagg
    15661 gctacatcga gcgcctcggc gagctcgggc tggaggacgc gagcttcgac gtgatcgtat
    15721 cgaactgcgt gatcaacctg tgcccggaca aggccgcggt gctgcgcgag gtcttccgcc
    15781 tgctcaaggc gggtggcgag ttctacttct ccgacgtgta tgccgaccgc cgcgtgcccg
    15841 ccgcggtgcg cgacgaccct gtgctgtacg gcgaatgcct gggcggcgcg ctgtactgga
    15901 acgacttcct cgcgctggcc cgcgccgccg gcttcgccga cccgcgtctg gtcgaggatc
    15961 gcgcgctcgc ggtgaccgac ccggcgctcg ccgccaggct ggggaacatc cgcttcttct
    16021 cggcaacctg gcgcctgttc cggatcgacg gcctcgacag cgccggggag gactacggcc
    16081 aggcggtggt gtatcgcggc accctgaccg ggcagcccga gcgcctcgcg ctcgacaagc
    16141 ggcacgcctt cgatgcgggc cgcgtcgagc cggtgagcgg caacacctgg cgcatgctgc
    16201 acgacagccg gctgcggccg cacttcgact tcgtcggcag cttcgaacgc cactacggcc
    16261 tcttcgccgg cgaggggctg gccatgccct tcgacaccgc gtcgcccgcc gcgggcggcg
    16321 atagcccggc gacgccggcg cccacaccgt cacccacacc gtcacccact ccggcccccg
    16381 cgaccctcgg cagcgcgacg cgcaagtcct gctgctgaac agcccccctc cccgagcccc
    16441 ctcatgaaga aagccctcct gctgctgctc gtgctagcgc tcgccgccgc cttcttcgcc
    16501 agcgggctgc accgccagct cgatctcgac gccctcaagg ccggcatggg cagcttcgcc
    16561 gcctggcgcg aggcctcgcc gctgctcgtc gccgcgctct acttcgccgc ctatgtggcg
    16621 gtgaccgcgc tgtcgctgcc cggcgcggcg gtgatgacgc tggccggcgg cgcgctgttc
    16681 gggctgggct ggggcctgct gatcgtgtcc ttcgcgtcca cgatcggcgc cacgctggcc
    16741 ttcctggtct cgcgccacct gctgcgcgac agcgtgcagg cgcgctttgg cgagcgcctg
    16801 aaggcgatca acgacggcat cgcgcgcgac ggcgccttct acctgttctc gctgcgtctg
    16861 gtgccggcct tccccttttt cctgatcaac ctgctgatgg ggctgacgcc gatccgcacg
    16921 cgcaccttct actgggtgag ccagctcggc atgctgcccg gcacgctggt ctacgtgaac
    16981 gcgggcaccg agctcggcgc ggtggacagc ctcgccggcg tgctctcgcc cggcctcgtc
    17041 gcctccttcg tgctgctcgg cctcttcccg ctgctcgcgc gctggctgct cgcacgcgtg
    17101 caggcgcgca gggtgtatgc ggggtggaca cggccgaaac gcttcgagcg caacctggtg
    17161 gtgatcggcg ccggcgccgc cgggctggtg acctcctaca tcgccgcggc ggtgaaggcc
    17221 agggtcagcc tggtggaggc cgggcgcatg ggcggcgact gcctcaacac cggctgcgtg
    17281 ccgagcaagg cgctgatccg cagcgcgcgg ctcgcccacc acatccgcca cgccgagcgc
    17341 tacggcctga cggccggcga accgacgatc gacttccgca ggctgatggc gcgggtgcgc
    17401 gcggtgatcc gcaagatcga gccgcacgac agcgtggagc gctacaccgc actcggcgtc
    17461 gaggtgctgc agggccgcgc gcgcatcgtc gacccgtgga cggtcgaggt ggcactcaac
    17521 gagggtggca cgcaccggct cagcacccgc aacatcgtca tcgccaccgg cgcgcggccg
    17581 acggtgccgg cgctgcccgg gctggaggcg gtgggctacc tcaccagcga cacgctgtgg
    17641 gacgccctcg ccgaactcga cgccccgccg cgccggctgc tggtgctggg cggcgggccg
    17701 atcggctgcg agctggcgca ggcctgcgcg cggctgggat cgcaggtggt gctggtgggt
    17761 cgcgcgccgc agctgctgcc gcgcgaggac gccgacgtcg ccgccttcgc ccgcgccgcg
    17821 ctggaggccg acggcgtcga ggtgctgacc ggggtcgtgg cgctgcgctg cgagctggag
    17881 caggcggatg acggcgcgcg caagttcctc gtcgtcgccg accccgcgag cggcagcgag
    17941 cgccgcatcg gcttcgactt cctgctgtgc gcggtcggcc gcagcgcgcg cctcgagggc
    18001 ttcggcctcg aggcgctcgg catcccgacc ggcgcgacgg tggagaccaa cgacttcctg
    18061 cagacgcgct accccaacat cctcgccgcc ggcgacgtcg ccggcccctt ccagttcacc
    18121 cacgtcgccg cgcaccaggc ctggcacgcc gcggtcaatg cgctgttcgg ccacctgcgc
    18181 cgcttccgcg tcgactaccg ctgcgtgccc cacaccacct tcatcgaccc cgaggtggca
    18241 cgcgtggggc tgaacgaggc cgaggcgcgc gcgcgcggca tcgccttcga agtcacccgc
    18301 tacgggctgg acgaactcga ccgcgcgatc gcggacggcg ccgaccacgg cttcgtcaag
    18361 gtgctgaccg cgcccggcaa ggaccgcatc ctcggcgcca ccatcgtcgg cgagcacgcc
    18421 ggcgagctgc tcgccgagtt cgtgctggcg atgaagcacg acctgggcct gaacaagctc
    18481 ctcggcacca tccacgccta tccgaccttc gccgaagcca acaaggccgc cgccggcgaa
    18541 tggaagcgcg cgcacgcacc gcagcgcgtg ctgcgctggc ttgaacgcca ccacgcctgg
    18601 ctgcgcggct gacgcggcgc gcgcctcagg cgcgctggta gcgcatccgg ctcgacagca
    18661 cgaggccgac cagggacgcg agccccgtga tcacccaggt ccactgccag ccgccgacca
    18721 tgccggccac ccaggccacc agcggcggcc cgaggaactg gccggccgag gagcactgct
    18781 gcatccagcc cacggtggtc gacaccgtat gctcgtcggg cgccacatgc accgcgagcg
    18841 cgaacagggt cgccggaatc aggccgccga tcgccgagaa cagcaccacc gcgaggtagc
    18901 gcgccaccgg cgcctcggcc gtgagcgggg agaaggcgac gaaggcggtc gccgccatcg
    18961 cgaggaagcc ggcgtagagc aggtggcgcg cacacacgcc gcgatgcagc aggcggccgg
    19021 cggcgacgtt gccggtaacg ttggagaggc aggccaaggc ggtgagcagc ccggcgagct
    19081 gccccgacag cccggcctgg gcgtagatcg ccggcaggaa gccgatcacc gccagccact
    19141 ggctcgaata caccgagaag gtgatcgcga cccgccacgg ccccacgctg ccgagcgtgg
    19201 cacgcaggcg cgcccgccat tgcgcgcgcg ccgggacggc ggcccccgcc ggcatcgccg
    19261 ccatcgcacg gcgcacccgg tcggaaggca cgcgcaggaa cagccagccg gccaccgccg
    19321 ccgacgccat cgccaacgcc acccagagtc cctgccagcc gatcgccccc atcagcagcg
    19381 gtccggcggc gagcaccagc gaggtgccgg tggccatgta ggtgccccac aggccgaggt
    19441 gcagtgccag ccggctgggc ggcacgagct ggcggatcag gctgggcacg ggcagtacgc
    19501 agagcaggaa gccgaagccc tcgatcgcgc gcagcgcgag cagctcgccc ggctgggtcg
    19561 cccacgcgcc ggcgaggctg gcggccacga gcacggcctg gccgagcagc acgctgcggc
    19621 gcaggccgaa gccgtcggcg gccaggccga tgaagacgcc gccgagcatg cctgccatct
    19681 gcaccatgga gagcaggaag ccggcctcga ccaggctcag gccgagcgcg tcgcgcagca
    19741 ccgggatcgc cggcgggatc ttgccgatgt gcagcgcggc gaccatgccg gcgatgatga
    19801 cgacgaaggc gggcgggatg cccgccgccg cggacggcgc gtgcccgccc aagcgcgggg
    19861 atgcgtctgt gctgctcatg atctcctctc tgcctctgga cgggccacga gagcatagcc
    19921 gcgatcgcct gcgtacgctc gcgcggcgac cggccgcatg cgcggccggc ttggtcgccg
    19981 gccctccggc cgtgtacatt ggcgaccact gccgcctccg cgcgtccgcg ccccgcccgc
    20041 catgacctcc ccgcaccccg aaatccgccc cggccagtcg gtcgagctgc tcaagcagtt
    20101 gcacatcctg acccgcgacg gcaagctcaa ccaggacagc cggcgcaagc tcaagcaggt
    20161 ctaccacctc taccagttca tcgagccgct gctcgccgag gcgctggccg agcgccccga
    20221 catcgagctg gtcgaccacg gcgccggcaa gagctacctc ggcttcatcc tctacgacct
    20281 ctttttcaag gcgcaagccc cggacggccg catccacggc atcgagaccc gcgacgagct
    20341 ggtgatgagc tcgcgccggc tcgccgacaa gctcggcttc tcggccggca tgcgcttcca
    20401 gaacctcagc gtggcggatt cgatcagctc ggaccgcctg cccgcacgca tcgacatcgt
    20461 caccgcgctg cacgcctgca acaccgccac cgacgacgcc atccgcttcg cgctgaagaa
    20521 gggcgcgcgc gcgatcgtgc tggtgccctg ctgccaggcc gaggtcgccg cggtgctgcg
    20581 caggaacaag cagcaggcgc tacgcgaccc gatcgccgaa ctgtggcgcc acccgatcca
    20641 cacccgcgag ttcggcagcc acgtcaccaa cgtgctgcgc tgcctgcagc tcgaggccca
    20701 cggctacgag gtgacggtga ccgagctcgt gggctgggag cactcgatga agaacgagct
    20761 catcgtcgcc cgccgccagc ccgaccgacc gcgccagcgc gccgccgaac gcctcgccgc
    20821 gctgctcggg atgctcggcc tggaagagct ctccgagcgt ttcttcaccg gctgaccgcc
    20881 tgcctgcgcc gctgcggcca cggctcgaca cgctcgacgc gagcacgcgg gaaccatgcg
    20941 tttgtgctgc gctcgaaaat cctgtcacga ccgtgctgct agaatcggtg ggtccgccgc
    21001 attcggggga caggagacag ggcatgcggt ccgccgcgcc cacaatgaac cggaacatcg
    21061 aggaggacgg gtgcgggcgc atccggacca cacatggccg aaaccgaatc cccgctggcc
    21121 ttcctgctga ccaccccgta cgcgaaccgc tacccgcgca agctggtcga aggcttcccc
    21181 catgtcgctc ggcgcatcgc cgagctctgg gacgacaagg acaagctcgg cgaatacttc
    21241 accgagctca tggtgtcgaa tcgaccgaac cgccgcggct tcccgcccga ggtcggcgcg
    21301 gagatcgtgt acctgagcat ggcctacgac ctccacggtc cggtacgccc taccgcacag
    21361 gcggcccccg aggccaccac cagtccacgc gaggacgcct gggaccacga gcgcgcggtc
    21421 accgagctcg agcgcctcga catcccggtc acgatggcgc agttcgtgcg agcgctcgag
    21481 gccggcgacc agccgctgtg ctcgctcttc ctgcatgccg gcttcgacgt cgacagccgc
    21541 gacgcgcgcc agtggacccc gctgatgatc gcctgcttcc acggccgcga ggcgctcgcg
    21601 ctcgagctga tccggctcgg cgccagcgtt gacgcgcagg acgcggacgg ctacacgccg
    21661 ctgcactggg cctccgtgaa cggctaccag aaggtcggcg aagtgctggt gcgccgccag
    21721 gccgaggtca acgcagtcag caaggcgggg atcacgcccc tgctgcaggc cgcggcacgc
    21781 ggccacctcg gcgtggtgcg gctgctgatc gagcgcaagg ccaagctcaa cctcgccgcc
    21841 acggacggct cgacggcgct gctcaaggcg gtcgccaacg gccattggga gatcgtcaac
    21901 accctgctcg acgccggcgc ctccacgcag gcgacgatga agaacggcac caccctggtc
    21961 gacatcgccg cgcgctccaa ggacgagcgc atccgcgagc gcatcgccat cgccgcacgc
    22021 atggaggccc gcggtgacgc cccgatccag cgcgacgagc cgccgccgct caccggcacg
    22081 atctactgaa ggcggcacgg taaacgcatg gtggggatcc cctcggcggc gctggccgtg
    22141 ctggtggtgg cgctgacctc gctcgggccg ctctccaccg acttctacct ccccgccctg
    22201 ccggcaatcg cgcgcgccct gcacaccgac agcgccggcg tgcaactcac cctgtcggtc
    22261 tatctgctcg gcttcggcgc cgggcagctg ctcgtgggac cgctgtcgga ccgcttcggg
    22321 cggcggccgg taatgctgtg gggcatgctg gtcttcctgc tgtccacgct cgcgtgcgtg
    22381 ttcgccgagt cgctcgccgt gctggtcggc gcgcgcctgc tgcaggcgtt cggcgcctgc
    22441 gccggcccgg tactcggccg cgcggtggtg cgcgacctct acggcccggc cgagtcggcg
    22501 cgcatgctct cccacgtgtc caccgccacc gcgctcgcgc cgctgctggc gccgctgctc
    22561 ggcggctggc tcaccgcggc gtggggctgg cgcgcaacct tcgtcgcgct cgcggtgtac
    22621 gccgtgctgc tgatgctcgc ggtggcgatg ctgctgcggg agaccaaccg ccaccccgac
    22681 gccgacgcga tgcgcccggg gcggatgctg gcgaactacc ggaccctgct cgccgacccc
    22741 gcttaccgcg gtgcgctgct gatcggctgc ggcgccttcg ctgcgctgtt cgccttcatc
    22801 tccggctcgc ccttcgtgtt catcgagcac ttcggcctgt cgccgcagca gatgggcctc
    22861 gccttcgggc tcaacgtcac cggcttcatg atcggcacca cgctgtcggc gcggcactcg
    22921 cgccgcctcg ggccggcccg gctgatccgc cacggcgtgt ggatcggcgc ggcctgcggc
    22981 gtgctgctcg cggcgctcgc cgttgccggc ccgcaacacc cggcggcggt gatgctgccg
    23041 atgtggggcg tcaccgcggc gatcgggctg atcctgccca acgccaccgc gctcggcctg
    23101 gccggctatc cgaagatggc cggcgccgcg gcctcgctga tgggcttcgt gcagatgggc
    23161 ctgggcgccg gggccggcat gctggtcggg cacggcgtgc agcatggcac cgcggcgctc
    23221 gggctcaccg tcgccggcgg catgctgttc gcgctcgccg cgtggagccg ctcgcccgcg
    23281 cgctgagcgc ggacggcgtt cacaacagcg cgcgaccggc cgcgaccagc ccggcgatgt
    23341 ccgcctcgag cgcatccagg cgcgccgcca cgccgggctc gtcctgtgcg atcgccttct
    23401 ccagcgcttc ggccgcctcc atgatggcga gggcgcagat gaagccggcg ttgctgcgca
    23461 gggtgtgcat gcggcgggcc gccgcctcgc gctcgtcgca cgccagatcg gcgcgggtcg
    23521 ctgcgacgac cccggcgttg tcctcgatga agagcccgag cagaccaagg aacatgtcgc
    23581 ggtccttgcc gaggcgctgc atcgcgcgtt cgcgctcgat gccgggcagc acgggaaact
    23641 cgtcgccggc cgtggcggac gccgccgcgg cggcctgcac cggcagagca gtctcgggtg
    23701 caaaaaccgg catggccgcg gcggcaatcg cgcggacggc atccgcgccg gatgcgggcg
    23761 tcgcctcgcg caagcccgtc ggctccaccc agcgcagcag cagcagcgtc atctgctcca
    23821 ggtccatcgg cttgggcagc acgtcgtcgg cgccggcggc gcgcgcggcg gcctgctggt
    23881 ccgcgcccac gccggcggtg aaggcgatca ccggcagcgc ggcgaggccg agctcgtcgc
    23941 ggatgcggcg agtggcggag aggccgtcca gcaccggcat ctgcacgtcc atcaacaccg
    24001 cgtcgaaggc ccgcggccgg ctgcgcagca gctcgatcgc ctgctggccg tcggcggcga
    24061 gggtggcctc ggcgccctcg agcgccagcg cgcgctgcac caggtcgcgg ttcatcgcgc
    24121 tgtcgtccac caccagcacg tgcatgccgg ccaggcgcga cccggacgcg gacgctgctg
    24181 cgggcgccgg gatggcggcg ctggccggct cgctgccggc gacccgctcg agcggcagct
    24241 cgaaccagaa ggtgctgccc agcccgggct ggctgcgcac gccgatcgcc ccacccatga
    24301 gctcgaccag gcgcttgcag atcgacaagc cgagcccggt gccgccgaag cggcgcgcga
    24361 tgccggcgtc ggcctgggtg aaaggcgcga acaggcgcgc ctgtgcctcg ggcgcgatgc
    24421 cgatgccggt gtcccgcacc tccgcgtgca cgcgcagctg cgcctcctcc acctcgtccg
    24481 tgcgcacgcg cacggagacc tcgccgcgct cggtgaactt gatcgcgttg ctgaccaggt
    24541 tgatcaggat ctgctcgatg cgcaggccgt cgccgcgcag ctgcccgggc ggcagcgctg
    24601 gcggctcgat gcgcagcgcg agccccttcg cgcgcgcggc ctggcccatc aggctgtcga
    24661 gattggcgag cagcgcgcgc aggtcgaagg gccgcggctc gatgcgcagc tggccggcct
    24721 cgatcttgga gaggtcgagc acgtcgttga ggatcgccag cagcgactgc ccggcgccgc
    24781 ggatgcgccc gaccatgtcg cgctgcgcgg gcgcgagcgg ctcgcgctcg agcacctggg
    24841 cgagaccgag caccgcgttc atcggcgtgc ggatctcgtg gctcatgtgg gcgaggaact
    24901 cgctcttggc ggcgttggcc gcggcggctg cggccgaggc ctggcgcagg cgctcctcca
    24961 tctcgatgcg cgcggagatg tcctcgacga tgcccaggta gcgcggcgcg tcctccgagg
    25021 ccacctgcac cggcgcgaag gccaggctta cccacaccgg cgtgccgtcc ggacgcaggt
    25081 agcgcttgtt caggcggtag ccgtcgatgc gcctggcgtc caggcggccg agctggcgca
    25141 ggctctcggc gacgtcgtcc gggtgggtga gcgccatcgg gtcggccccg accagctcgc
    25201 cgacgccgcg gccgacgatc tcggcgaagc gcgggttggc ctcggtgatc cggcgcgtgc
    25261 gcgggtcgag cagcaccacc cccagcggcg cctgctcgaa gatcacccgg aagcgcgcct
    25321 cggcggcctg gcgcgcctgc agcgcggcgc gctcgcgctg ctcgcggtcg cgccgccaca
    25381 ccaggtagcc ggcggagtac accagcatga ggccgagcgc catcaccacg cccatgcccc
    25441 aggtcagcgt gcggatgccg gcataggcct cgcgctcgtc gatctcggcg agcatcagcc
    25501 agggcgtgcc ctcgaccgca gcggcgtagg ccagcaccgg cacgccgcgg tagtcgcgcc
    25561 cgccggagag gatgccgcgc tcgccgagcg ccgcgcgcgc ggccggcagg tcgggggtgg
    25621 cgagcgggcg ctcgagcgcg agcgccgcgc cggcctgatg gcgcagcggg gtcaggaagc
    25681 gcaccccctc gccatctcgc cgcaccagat aggtctcggc gctgcgcgtc ggcaccggcc
    25741 aggcctcgac catcggatac agcgcggcct cggcctccca gctcaggtag gccacgccgc
    25801 gcgccggcac gcccaccggc gcgagcacgc cgtagtgcgt gcgcccttgg gcatcctcgt
    25861 gcaggtcgac aaactccacg cgcggccgcc gcagcacgtc ggcgatccgc tccgcatggg
    25921 tggacaggtc cgggctgccg accacgagcg cgggcgcgcc ctccgcatcg atcagggcca
    25981 gcccctgcca gccgcgcagg cggacgagtt cctcgacgag cgcctgcatg cgcgcgtacg
    26041 ccacctcgtc gcgccgaccg ccgtccaccc agccggcgaa caaggcctcg agctgcgaat
    26101 ggccggagaa caccatctgc gcatccaccc gcgcctcggc gagccagccc tcgatgtgct
    26161 ggcgcttctg ctcggcgatg accgccagcg tgcgctgcgt ctcgcggcgg atctcctcgc
    26221 tcagcgagcg gtagccgaag gcgccgacgc cggcgaccag cacggtgagg gcgatgagcg
    26281 ggaaggcgag gcgccaaccg gcatggcggc ggccagggtc ggcggcatcg gcggcggaga
    26341 cgagtttcat ggcgtggagc gcgcgaccgc agccggggcg gtgtgcgcag gcgagaggat
    26401 gccggcattg ttgcgccgcg gcaggcgcgc tgcaacccgc accgggccgt tcagcctcca
    26461 ccggcgagga agagcgccgg atcgaccatg gtgcgattga gcatcaccga ccagtgcagg
    26521 tgcgggccgg tgacgcgccc ggtggcgccc accgcgccga tgcgcgcgcc cgcctccacg
    26581 gtgtcgcccg ccttcaccgc gatcgaggag agatggcagt acatggtgag caggccgcga
    26641 ccgtggtcga tccacaccgt gttaccgttg aagaagtagt cgccggtgtc gatcacccgg
    26701 cccgccgcgg cagccaccac cggggtgccg gtgggcgcgg cgatgtccat gccgccgtgc
    26761 ggcttgcgcg gctgatcgtt gaacacccgg cgcaggccga aggagcccga gcgccgcccc
    26821 ggcacgggct gcagcatgcg caggctgccc gggtcgaggg cgctccaggt ggcgacgatc
    26881 tcggccgagc gcaggcgctc gcgctcgtgg cgggcgaggt cgacgggcga caggtccacc
    26941 ttgcccggcg ccaccttcag gcgctgctcg gcgtagcgca cgggccccac cgcgacgggc
    27001 agccggcgcg gcggctcgtc ttctgcgcgc agttccagct ccaggctgcc gggcgcggcc
    27061 tcgagcggga tgcccaccac cgcggtccat ccgcccgggc ggccggccac cagcaccggc
    27121 acgccatcca ggctggcctg cggcgcgacc agcgcaggcc cgagctcgac cagggcgacg
    27181 ccgcccgcca ccgcgcgctc gcgcggcaac tccagcgcca cggcgggcag ggagaaagtg
    27241 gccgcgacga cgaccgcgaa ggcggccagg ccgcgggcga ggcatgcctg ccagccgcat
    27301 gcagaggaag cgcacatcat tcggatcctg gactcgggag cggcgccggc gcggcgtcac
    27361 gcccctggca tgacgccgcg ggcggtgtcg tggtggcgac cgatgccgcg atgataccgg
    27421 cgaaaaaccc ggcggtcgcc gatcggcgcg ctagaatcgc gccctcgctt acccgcccgc
    27481 gatccgggct tcatgacgaa acgccgccac ccgcggctgg agaccaaaca tggaagcatt
    27541 cgccaaccag gtcgtcgacc tgctcaacgg cctgctctgg ggcaagatcc tgatctggct
    27601 gctggtcggc accggcatct atttcaccct gcgcctgggc ttcatccagc tgcgccactt
    27661 cggccacacc ttcacggtgc tgcgcggcag ccgccgctcc gacgcctccg gcatctcctc
    27721 cttccaggcc ttgtgcacct cgctcgctgc ccgtgtgggc accggcaaca tcgccggcgt
    27781 ggcggtggcg atcacgctcg gcggcccggg cgcgatcttc tggatgtggg tgatcgccct
    27841 cgtcggcatg gccaccggct tcgccgaggc cacgctggcg cagctgttca agcagcgcga
    27901 cgacaagggc cagttccgcg gcggccccgc ctactacatg gaaaagggcc tgggccagcg
    27961 ctgggcgggc acgatgttct cgatcttcct gatcatcgcc ttcggcttcg ccttcaactc
    28021 ggtgcagtcg aacacgatcg ccagcgcgat ggtcggcgcc ttcgggctcg acctgggcag
    28081 cttgaccctg ggcggcaacg aggtcggcgt cgccgcgctg gtgatcggcg tggcggtcac
    28141 cgtgctcacc gcggcgatca tcttcggcgg cctgcgctcg atcgcgcgct tctccgagct
    28201 cgccgtgccc ttcatggcgg tcggctacct ggtggtggcg gtcggcatca tcctggccaa
    28261 cctcggcgag gtgccgggcg tgctggcgct gatcttccag agcgccttcg gcctgcacga
    28321 ggcggccgcc ggcggcatcg gcgcggccat cctcaacggc ttcaagcgcg gcctgttctc
    28381 caacgaggcc ggcatgggct cggcgccaaa cgccgccgcc gcggccacgc cctacccgcc
    28441 gcacccggcc tcgcagggct acgtgcagat ggccggcgtg ttcatcgaca ccatgctgat
    28501 ctgcaccgcg tccgccgcca tcatcctgct cgccggcccg gtcgagggca ccggcgtcgg
    28561 cctcgttcaa aacgcgctga ccagcgaggt gggcggctgg ggcaagtact tcctcgccat
    28621 cgtggtgctg ttcttcgcct tcacctcgat cgtcgccaac tacttctacg ccgagaactg
    28681 cctggtcttc atcgagcaca accaccccgc gggcctgctg atcttccgcc tgatcgtgct
    28741 ggcgatggtg atgttcggcg cgatcggctc gctgcccttc gtgtggaact tcgccgacgt
    28801 ggcgatgggc ctgatggcga tcaccaacct cgtcgccatc ctgctgctct cgggcctggt
    28861 ggtgaagctg gcgaaggact acaacgccca gcgtgccgcc ggcaagctgc cgagcttcga
    28921 cgcccgcgag taccccgaga tccgcagcag gctcgagccg ggcatctggg actgaggctg
    28981 gagacgcccg cagcgacgcc acccgggccg gacgccacga gcgtcccgga ccgggcccgc
    29041 cgcaccaccg ccgatccgat gcacagcctc ctcgagttcc ccagcccctt ccccgccgag
    29101 cccggcctgg tgcgcctgct cgagccgccc ggcagcgacc ccgccgcgct cgccgcccgc
    29161 ctggtcgcgg gcgactacgg caagcccttc gtgctcgaga acggcggcct gcgtgcgctg
    29221 cacttcagcc tcggctacgt gcagagcgtg atggacatcg ccaacccggc cgcgctcgtg
    29281 ctcgcctacg cgcgcgcgat gatggccttc ctgctgttca atccgcgccc gcgccggatc
    29341 ggcatgatcg gcctcggcgg cggctcgctg gcgaacttct gccaccgcca cctgccggcg
    29401 gccgagctga ccgtagtgga gatcgacgcc gacgtgatcg cgctgcgccg gcatttcggc
    29461 gtgcccgcgg acgacgcccg ctttcgcgtg ctccacgccg acggcgtgcg ctggctgggc
    29521 gagaccgaga cgcgcagcga cgtgctgctg atcgacgcct tcggcgccga gggcgtcgcc
    29581 gagaccctgc tcgacaccga cttccacgcc aatgccttcc gccacctggg cgggcgcggc
    29641 gtgctggtca tgaacctcgc tggaacgcgc gagtccttcg cgccccacgt cgcccgcctg
    29701 ctcgaggtgt tcgacgagcg cgtgatcgcg atgccggtgc gcgaggacgg caaccacatc
    29761 ctgctcgcct tccgcgaccc cgccttcgcg ccgcgctgga actggatgcg cagccaggcg
    29821 ctcgccctgc aggcgcgcac cgggctggac tttccgaatc tcgccggcgc gctcgaggcc
    29881 ggcgagcgcc agggccatgc ctggcggctc gcgcgctgag cggacggcct gcggcttttc
    29941 ggggcggctt cagcgccgat tgttgaaggg gtagccgtac aggcgcagca gctggcggaa
    30001 ggcctcggcg ctgagcgcgg gatcgtagct ggagaagagc ttgtgctggc gctcgtgcag
    30061 cgtcgcggct tgtgccgaca gcagcatctc gcgctcgtcg aggatgtcgt cgcgcatgcg
    30121 cgggctcacg aacaggaagg ggatcggccg gtacaggccg tcgtcggacg aaaggtgata
    30181 acgcgggtgg gcgatctgga cgttctcggc gagatgactc ttcatggctc cgtcgtgcgg
    30241 tcgaaaggga cgcctgtccc gcaccatgcg ggatcagaag gcgatgggcg cgggccaaag
    30301 gccgacgcgc cccgttgaac gaccatggaa gcgcaaaaaa gatcccgccg catgcgtttc
    30361 gcacgcagcg acgacggcgc ggtggcgctc aatgcgagcc ggcgaagggg tagcgataga
    30421 gctcgagcag ctcggtgaaa ccgcgcgcgc ccgccaccgg gtcgtagcgc tcgaacagct
    30481 tctgctgacg tgcgcgctgg gcgggcggca aggtcgcgac cagcagctcg cgctcgtgca
    30541 ggatgtcgtc gcgcatgcgt tcggtcacga acaggaaggc gatcggggcg tagaggccgt
    30601 cgcgggtctg caggtgaaaa cgcggcctgg caatgcggat gtcttcggcg agatggcttt
    30661 tcatggtctt gggctcgctg gctatgggtc tccgtccttc tctttgcatc atccgtcata
    30721 cagcccgcac cgggtagctc gaaagtctcg cagggctgca atccgtcacg ctcgcgcgca
    30781 gacggcgatg ctcggcctca attcggcctg agcgcgcgct cagcgcgccg gctttgcggc
    30841 ggcacccgcc gagccgcagc tcgcggcaag ccagcgtgcg tcggtctcga gatcgaggtc
    30901 gccgcgcacc gaggcgagcc ttacccgggt gacgaagtgc tccgggcctt cgacgcgggc
    30961 atggaagtcg ccctcggcgg ccggatcagt gcagctcagg ctgccgcgga tcgtgttgcc
    31021 gctgcgctcg acccgggtca gcgtgcagtt gccctcgacc ttgccggcga agatgttgtc
    31081 ctggcgcgcc tgctcgggcg tgatgcagct gcgtacgctg ccgtccgcgc ccaggctcac
    31141 cccgcgctgc tgcatctgct gctccagcat gcgccgggtg tcggccggca ggcccttgat
    31201 gtgctgctgc agcatgccca tctgcgcgga catgtccggc agcccggcca cgctcaggcg
    31261 cgtggagcgg aattcccaca ggccggggcg gaggttgtcg agcgcgtggg cggcctgcgc
    31321 ggtgcaggcc agggcgagtg cgagcgcggt ggcgcggagc ggggtcatcg gggcggtcct
    31381 cgtggtgcgg cgagcgggcg gagaggcgcg cccggcttcg aagcctgcat tatcgcaggc
    31441 gaggcgccgg agacggctca tcgcagccag gcaagatcgt gagcggatct ttcgacgcca
    31501 cggcgcgaga ccgtgcagcc cgctaccgcg gcgcgacccg cccggccagc gcgagcagcg
    31561 cggcgtgatc cgccagtcca tcgacgaagc ggcgcgggat ccccttcagc cccacctgcg
    31621 cccccaccag cgcccccgtc agcatcgcgc gcgccagatt ctgcccgccg ccattgaccg
    31681 catgcagcac cgccgactcg aagtcgtcgg cgaagcgcgc cgccaggtaa taagcggccg
    31741 ggaactggtg atacaccgcg cacggcatgc catacaccag cgacaccttc cacgccggct
    31801 cgatgcgcac gtcggggtcg cgcgccgcgc gcgcgatcga ggattgcgtc agcagcgcat
    31861 cgggcgacgg aaagcggccg gcggtcgggg cctcggtggc gccgggcctg ggcgcctgca
    31921 ggtttcccac ggtcaccgtg tggaaaggca gcgcgccgga cttcacccgt gccatcagct
    31981 tcgccgagat cgccgcatcg agcctgtggc cctcgaccag catgccgagc acggcgccga
    32041 aggcgaccgt catcgccacc acggtaccgt cggtttgcgt cagcacggtg ttgcgggtga
    32101 cggcgtcggc gagcgcggcg gggtcgagcg cgtagcgcac cgcgatcgcc agcgtgcgct
    32161 cggcggcctc ggtggtgtcg gcgttgccgc cgacctggcc ccagggcagg cgctgctgca
    32221 cgcgcttgcg ccacgcttcg cggatcgact ggctggtgta gccgccgggg ccctgcatcg
    32281 ggcggccatc cagttgcggg aagagctcct cgtccaggcg gcggcagaag tcggcctcgt
    32341 cgtagccgcc gcagtcggcg agcgactcca gcgtcaggcg cagcaggatg ccggcctggg
    32401 aggattcgcc cgccttcatg ccggcgtggt agtggtcggg catcggcgcg gtgtagtccg
    32461 agatccacga cccgtagcgg gcacgcagct cgtcgaggtc gtagtaccag tgcgggccga
    32521 gggccagcgc gtcgccaatg aaggcgccca tcagcgcgcc ggcagcgcgg tcgatcacga
    32581 cttcgcggtc gatgggagtc atgcgcgctt tctccagatg gtcagttccg acagcgtgtg
    32641 ctggtgcttg cgccgcgtct cgcggatcac gaagggcacc gcctgcggcc cctgcaccag
    32701 ctcgaagtcg gcggcgagca ggtccttcag cccgtcgagc gtggtgtagg actcgccgtc
    32761 cttcttgaag ccgccgatcc actcctcgcg cttggtgtgc tcttccagcc aggtgtaggg
    32821 cgaggcgagc agcagcaggc cgcccggatt caggcggcgg gtcacgtcgg cgaggaagcg
    32881 gcgcgggctg tacaggcggt cgatcaggtt ggcggcgagg atgaggtcga agccggtgaa
    32941 cacgtccttg aggttgcagg cgtcgccctg ccagaactcg acgcgcccgg cggtctcggc
    33001 gaggccgagg gcgtcgagcc ggcgctcgtg gtaggtcacc agctcgccct cgtcgggcat
    33061 ggtgtagcgc agcacgccgg tctcggcgag cttgaccccg gcctggatga agcgcgccga
    33121 gaagtcgatg ccgaccacgc gttcgaaggc gcgcgcgagt tcgaagctgg cgcggccggt
    33181 ggcgcagccc agatccagcg cgcggccgaa ctggccgttg ccgaagcggc gctgggcgct
    33241 gatcgcaatg tcggcgagcg ccttcgggaa gttgggcaca ccgaaggcct cgtcgccgta
    33301 gtggaactcg gcgtactgcg acagcagcgc gtcggtctcg taggtcgagg ccggattgag
    33361 caccggcgcc tcgctgacga tgtagcgcaa gcctgcgtgc tggaagaagt ggcggcggaa
    33421 ggcgtagcgc gaggcgtggc gcgactcgtt gcccgccgag atccagctgc cgcccttgat
    33481 gatgccgtgg cggtcgtcga aggtcggcgt ggtgaagtcg tcgtagatcg gatgcacgtc
    33541 gaagccgtcg aagggatagg tcggcgtctc gcaccactgc cagacgttgc cgaccacgtc
    33601 gaagagctcg ccatgcgcga agcgcgtcac cgggcagctc gaggcccagt ggtcgaggtg
    33661 caggttggcc ttggcgggtg cgtcgtgcgg cacgtcggcg aggcccacgt ggtcgtagat
    33721 gcggttccac tcgtcctcgg tcggcaggcg caccggctgc ccggtctcgc gcgccttcca
    33781 gcggcagaag gcgcgcgcct ccaggcaatt gacctccacc ggccagtccc agcgcatcgg
    33841 cacttcttcg gtcatcaggc gcagcttcca gcctgccgtg tcgggcaccc agaaggtcgg
    33901 gtgctcggca cgcgcgtaac gcttccagcc caggccctcc tcgtcccaca gggcatcgtc
    33961 ggcgtagccg ccagcctcga cgaagccgag gtactcacgg ttggtcacca ggtagcgcgc
    34021 cgcctggaag gccggcacct cggcgcggtg cgtgccgtac tcgttgtccc agccgtagat
    34081 cggctcgtcg aagctgcgtc cgagctgcac gacgccggcg gggatgtcga ccagcgcatt
    34141 ggccggcggc tcgccgtact cggtacaggg cggccaggcg ggatgcggct tgacgtactg
    34201 cagcgcgtgc tggcgcatca gcaccgacga ggtctcgagg tggatacgct catgctcgat
    34261 gcccatcacc accgcccaga acggatcctt ccagccgatc ggcaacgtga agggcgtctc
    34321 gcagatcacg cggtcgacca ccgcgcgcac cttgttccgg tagtcagcga cctcggccac
    34381 ggtgggccag tcgtagcgcg cgtcgtcgag gtcgtcccag ctcatctcgt ccacgccgac
    34441 cgcgaacatg gactcgaggc gcgggtcgat gcgctgctcg atcaggccgg cgagcatgaa
    34501 cttgttgatg aagaaggtgg cggtgtggcc gaagtagaag atcagcgggt ggcgcaggct
    34561 gatcgatttc ttgtagtagg cctcgtcaca ggcgagcacc tcgaacagcg actcgtagcg
    34621 gtcgaaggtg gcgtggaagt actgcagcag ctcggcgcgc ttggcctcga cgtcgctgcc
    34681 ggcgagcagc ggggtacgcg gaaagaggga cacggggctg ccggcgggag aggagacttg
    34741 ggcaggacga gcgctcgggg tcgcttgcga tgctgggttc attgcgggga tcctggtcgt
    34801 gggggacgga tggagtgcat tttccacgtt tcggcgcggg aaggtagcgc gagcgcgagc
    34861 gcgggccccg agagcccgaa tgcggcggag gacgctccgc acgcgcgtcg actgccgggc
    34921 gccccgttcg cgcctgccgg cgctcctacg gaaaccgccg cgacccgggg tgggatgtgg
    34981 gagcggcggc cgccgcgaat gcagctgccc gcgatcgaca tggccgccgc ggcccgccgc
    35041 cgcgttcgcg cctgccggcg ctcctacaga aaccgccgcg gctccgggtg ggatgtagga
    35101 gcggcggcag ccgcgaatgc agcagccccc gatcgacgcg gctgccgcgg cccgccgccc
    35161 tgttcgcgcc tgccggcgct cctacagaaa ccgccgcggc tccggatggg atgtaggagc
    35221 ggcggcagcc gcgaatgcag cagcccccga ccgacgtggc ggccgcccgc cgttgtggcg
    35281 gtggcgatcc tacgattttc cgattacctt gcggagcgat gaagacccct tccaagccct
    35341 tcgtgatgaa ccgccacccg gcgctttgct cctgccgcga ggccgcacga tgagcagcca
    35401 gttccgcctg ctgcgggagc gccgcttcct gcccttcttc ctgacccagt tcctcggcgc
    35461 cttcaacgac aacgtctaca agaacgcgct gatggtgctg atcaccttcc aggccgcgcg
    35521 cctgggggcg gactcgcctg gtgtgctggt aaacctcgcg gcgggcgtct tcatcctgcc
    35581 cttcttcctg ttctcggcca ccgccggcca gctcgccgac aagtacgaga agagtcgact
    35641 gatccgcgcc accaagctgc tcgagatcgc ggtcatggcg ctggcagccg tcggtttcgc
    35701 gcggatgtcg ctgccgctgc tgctcgtcgt gcttttcctg atgggcatgc agtcggcgct
    35761 gttcgggccg gtgaagtacg cgatcatccc gcagcagctc gccgacgacg agctggtggg
    35821 cggcaacgcg ctggtggagg cggcgacctt cgtcgccatc ctcgccggca ccatcgtcgg
    35881 ggggctgctg gtgatggggg aggccgggcc cggtcgcgtg gcggtcgcgg tgctgggaat
    35941 cgcgctgctc ggctggtggt ccagccgcgc catcccgccc gcagcggcgg ccgatcccgg
    36001 gctgcgggtg aattggaacc cggtgacgca gacgcgcgag atgctgcgct tcatgctcga
    36061 ggcacgcacg gtcttcgccg ccatcgtcgg catctcgtgg ttctggttct acggtgcctt
    36121 gtttctgtcg cagtttcccg gcttcgccgc ggatcatctc ggcggcgacg agcgcgcggt
    36181 gacgttgctg ctggcgctgt tctcgatcgg catcggcgcg ggctcgctgc tgtgcggccg
    36241 cctgtcgcgc gggcgggtgg agccgcgcat ggtgctgccg ggggcgatcg ggctgagcct
    36301 gttcgcgctc gacctgtggt gggcgagccc ggcggcgggg gccttcgcac ccggccagga
    36361 actggccgcg ctgttctccc gcgcggaggt gtggcgggtg gtgttcgacc tggtgatgat
    36421 cggggcgtgc ggaggtttct tcatcgtgcc gctgtacgcg ctcgtgcagc agcgctcggc
    36481 gccggcgcac cgcgcgcgcg tgatcgccgg caacaacatc ctcaacgcgc tcttcatggt
    36541 cggcgcggcg gcgatgggcg ccggtctgct cgccgcgcgt ctcgcggtgc cgcaactctt
    36601 cctcgtcacc gccgtgctca acgcggtcgc cgccgccgga ttgttcgcca gcgagcccgc
    36661 cttccgccga cgcagcgccg ctcctacatc ccaccccggg ccgcggcggc ttccgtagga
    36721 gcgccggcag gcgcgaacag ggcggcgggc cgcggcggcc gcgtcgatcg gggacggctg
    36781 cattcgcggc tgccgccgct cctacatgcc accccgggcc gcggcggctg ctgtaggagc
    36841 ggcggcgggc gcgagtcgcg atcggtggct tgcgctgcta cgatgaagca gactcaccgg
    36901 tgcgatcgac gccaccggac cgcaccggag ccaagctcat gaatcccctc ctcgccctcc
    36961 tgctcgcgct cgcctccttc accgcctgcg cccagtccct gcccaggggc gactgtgccg
    37021 ccccggcggc ggcacatgac ctcaacggct gcgacttctc cgggcgggat ctcaccggca
    37081 tcgacctgcg cggtgccgtc ctcgacaacg ccagcttcgc cggcgcaagg ctcgacggcg
    37141 cgcgcttcga ccaggcctcg gcgcgctggg tgaacttccg caatgcgcag ctcaaggcgg
    37201 cgcagtttcc cgacgccgac ctcttccacg ccaagttcga cggcgccgac ctcagcgacg
    37261 ccaacctgca gcgcagctac ctcttcggct ccaacctgat cggcacgcgg gcgccacgtg
    37321 ccgacttcag cggcgcccac ctcaaggacc tactgatgcc cgacgccgac ctcgagggcg
    37381 cgcggctgcg cgactgcttc gcgctgcgtg cggtgctcgg cggctcgcgc atggcgggcg
    37441 cggacctctc gggcagcgac ttcaccggcg ccgaggcgga ggacgtcgat ttcagcggcg
    37501 cgaccctgcg cggcacgcgg ctcgccggcg cctcgctggc gggtgcggtg ttccgcgagg
    37561 ccgagctcga gcgcgccgac ttcacccacg cggatgtcgc ccgcagcgac ttctcgcgcg
    37621 cgcgcaacct gcccgcgcag gtcaccgagc tcttcatcgc gccgcagatg gggatggcca
    37681 ggtgagcgag ccggggagca ggcccgggac aatcgcccgc ctcctggcct acaatacgat
    37741 ctctttccac cgatcgtgcg ccgcatgaac ctgcccgccc gcctccgcct cgcccatcgt
    37801 cgcgcctcgc tgcgcgcggg cgtgcgtgtg cgcgcgcgcg gcatcgtgtc gccgctgcgc
    37861 gatctcgcga cccagctcgc gttcaaggtc acaggatctc ccgccgtgct ttcccaagcc
    37921 gtgcggggct accacagggg ctgagcccca ccccccgcac ggcaccttgc ccgggacgcg
    37981 cacggcgcgc ctcccgttca acgtgcagcc gccgcgggtc tctcactcca gcttcccgcc
    38041 catcgaccgc tcatcgacaa gcctggcggt ccggccacgg tccatccgga ccctcccggc
    38101 catcggcatt gccccgcgcg gctgcacccg gaacgccacg cccgccgcgt ggcgatgcga
    38161 tgcgatgcac gagggtgatg cgatggttct cacacgaagt ttcgtcaggg cgaagcggcc
    38221 ctgcaccgat ggattccgct ggttcgtccg ccagttcggc gaaggcggcg actaccaggc
    38281 catgctcgac gggatggtcg ccgccggccg catcggcgac gcctgctggc tgctcgagca
    38341 gttcggcccc accgacgagc tgcgcgtggt cgacgcgatc gaggccgacg ccatcgtgtt
    38401 tgccggcacc ctggaggtgc gcggcggcgt ggacgtcgag ggcgtgctcc gtgtcgggcg
    38461 ctcgctgcag gccggcgccg gcgtgcgcgc gggcggcgac gtccgggtcg gcaccgacct
    38521 gcgcgtggaa ggcagcgtgc gcgtcgaggg cgacctgcag gtcggtggcg acctgcgcgt
    38581 gggctgggga gtggactgcg ccggcgagct gcgctgcgac ggcgagctgc gcaccggctg
    38641 ggacctgcgc tgcggcggcc gcctgcgcgt cgccggcaac gcgtacgtcg gactcgacct
    38701 gcaggccgac gagggcgtgc gttgcgccaa gggcctgcag gcgggcggcg acatccaggt
    38761 cgagaacacg ctgcgcgccg cacagggcat caccgcgggc ggctcgatcc gcgccggcat
    38821 gcacctcgag gccggctggg gcatcaaggc cggcggagtg atcgccgccg cgggcgcgat
    38881 ccgcgccggc gagagcctgg ctgcaggcga ggcgatccgc gcgggcgccg gctacggcgt
    38941 gttcgcgggg ctcgacgtgc agatggaggc ctgggaggcg agcgcgcggg tgagtgcacc
    39001 gcagcgcccc gaaggcctga tgagcggctg gtgggccggc cccgcggcgt gctgagcgga
    39061 ggacgcgcaa tgaacaccct cgccctgcgc ccgcgcggcc tgctcgcccg caacaccccg
    39121 ctctcgcacc gctccagctt ctcgccgcgc gcggcgctgg ccttcccgca gccaccgccg
    39181 ctcgccgccg cgcgggccgc ggccgtgcgc gccgcgctcg gcaatgcgtt caccgccgtc
    39241 ctgcgccgcg tgctgcagcc gtcgcgcatg gaactgcgca tcgacgtgaa tcagcccgac
    39301 gacagcatcg aggccgagct cggcatcctc cacggtcggc tccaccgccc ctgcgacgcc
    39361 ctgcacgcct gcacccgcct gcccgccctg ctgcccggcc tggtcttcca ccaccgcgag
    39421 gccgacggcg agcactacgt ctatgtggaa gacgccgcgc acgggcgcct cgccggctac
    39481 acggtgttca accgcctgat cgaggttgac cgccgcaccg accgccacgt gcgctcgccg
    39541 cactccaaat acgctcccgc ctaccagggc cgcggcatcg ccagcgcggt gtatgcctgg
    39601 gcgctcggac gcggcctgtg cctggtcagc ggcgcccgcc agtccgccgg tgcgcacgcg
    39661 ctctggcacg ccctcgcccg ccgccacccc ctgcgctggg tcgcgctgcg cgccaagcgc
    39721 atgcacgacc tcggcgccag cgtcccgtcc gcccaggcgg ccgagctcga cacccgcatg
    39781 atcctgctcg gccacggctg gagcgccgcc cgactgcgca gcctcggcct gctgcatccg
    39841 gccgccgagg cagccaacga gaagatgcgg cggcgggcct gaggcgcggc gcacgctcgg
    39901 ccgtgttcgc gcctgccggc gctcctacag gggcggcggg ggcggagcgg cgttcgcgct
    39961 acagaaaccg ccacgcgtcc cggacctcgt gtaggagctg cggcagctgc gaatggagcg
    40021 gttcggcgac cgcggcgccg gaaggagccc ggacgccgca ttcgcgcctg ccggcgctcc
    40081 tacatgaacc gccgcggtcc ggcgcgatgt aggagcgccg gcgggcgcga atggattgcg
    40141 ggagcgcctg ggtgtgcggc ggcgctagaa tgcgggtttt cgggccgaag cgcccgcctg
    40201 cgccgtctct tccggaacgc cgacatgaaa ctccccaccg ccgccgcgct tttcctggcc
    40261 acctcggccg cactgaccgc ctccaccgcg ttcgcgcagg atctgcccaa gggtgactgc
    40321 gccgcgcccg cgccgcgcca ggacctcagc ggctgcgact tctccggacg cgatcttgcc
    40381 ggccgcgact tctccggcac ggtgctcgag aacgcgcgct tcaacggcgc gcgcctcgag
    40441 ggtgcgcgct tcgagaaggc gatggcgaag tggaccaact tcaccggcgc ccgcctcgag
    40501 ggcgcgcgct tcgccggcgc caacctgttc cacgcccgct tcgacggtgc cgacctgagc
    40561 gacgccgacc tgcagggcgc caacctcttc ggcgccttcc tgatcggcac ccgcgccccg
    40621 cgcgcgaacc tcgacggcgc gttcatgaag gacacccaca tgcccgaggc cgacctcagc
    40681 ggcgcccgcc tgcgcaaggt gtatggcctg cgcttcatcc tcgacggctc gaagctcgcc
    40741 ggcgccgacc tgtccgaggc cgacctcacc ggcgccaacc tggaagcggt ggacttcacc
    40801 gcggcccggc tcgccggcac ccgcctgtcg ggcgcggtgc tgcccgaggc gaagttcgcc
    40861 gacgccgacc tctccggcgc cgacttcacc catgtggacg tcgaggagag cgacttccgc
    40921 ggcgcgcgca acatccccgc ggcgctgcag gcgcagctcg acaaggctgg ccagggcaag
    40981 cgctgaatcg gctcgccgga gcgctgctcc ggatcacctc accgcacggg agctcgaccg
    41041 ctgcgttgtg cgctcggtgc cagtgcagcc ggcccgaacg ggtccggatc aagcgctcgc
    41101 gagcggactt gaagccctcc cggggcgccc gcgtgctcga gcgccgacgc ctcctcggac
    41161 ccggaggcat tggagcacac ggcgcacgcc gagccacgcg ccagttcgct cagtcgcccg
    41221 ccgtcgcccc gccgaagcgc tccgccagcc agtcgatgaa cacccgcacg cgcgccgaca
    41281 agggccggtc cgccgggtag agcgcgtgca ccggcagccc gggtggcgga aacccgggca
    41341 ggatctcgac gaagcgcccc tgcgccagcg gctcgcgcac gtggtagtcg ggaacctgga
    41401 cgatgccgaa gccggccgcg caggcggcca cgtaggcgcc gccgttattc acccccagcc
    41461 gcgaacgcag gctgcgcagc tcgatgcggc cttccacctc gaactccagc ggcagcgact
    41521 tcgcggtgga cgcggagacg taatccacca tccagtgcgc ctccagctcg tcgagggtcg
    41581 ccggcgccgg gtgctcggcg agatagcctg cgctcgcaca cgtcacctgg cgcaggcgtc
    41641 cgagccggcg cgcatgcagc ggcaggtcgc cgagctcgcc gatgcgcagc acgcaatcca
    41701 cgccctcgcg gatcaggtcg atctggcggt cgccgacgct gatctcgatg cggaccagcg
    41761 gatagcgcgc gtagaagtcg ggcagggccg gaatcagcag caaccggcag aaggaatccg
    41821 gcaggtcgat gcggatgcgc ccctgcggat ggtgcgcggc ctgtgagaac tcggcctcgg
    41881 cgtcgtcgag gtcggcgagg atgcgcaggc agcgccggta gtagcccgtg ccgtccacgg
    41941 tgggggtgac ctggcgcgtg gtgcgcgcga gcaggcgcac gccgaggtgg gcctcgagct
    42001 gctggatgat ctgcgtcgcc gaggcccgcg gcaggccgag ctgctcggcg gcgcggctga
    42061 agctgccgag ttcgacgatg cgggtgaaga ggcgcatggc ctgcagacga tccatggcgg
    42121 cgattattcg tataaaccga atagtgtagt tgttttgcgc gtctttatct gtcgccggca
    42181 aacagcgatc atccgtagcc cgacaccctg gccccgagcc cctcgaacgc catgctcgcc
    42241 cacctcgaac gccccgccgg ccccgccccg gggctgcgcc gcatcctcga cgacttcggc
    42301 ctgacctatt tcgccaacgg cctgatcggc ttcatctttt ccgccaccgg accggtcgcg
    42361 atcatcctct cggtcggcac ccgcggcggg ctcagcgagg cggagctcgc ctcctgggtg
    42421 ttcggcgtgt tcttcatcaa cgggctgatc acgctggcga tgagctggcg ctaccacatg
    42481 ccgctcggct tcgcgtggac catccccggc accgtactgg tcggccccgc gctgcagcac
    42541 ctgagcttcg ccgaggtcat cggcgccttc tacgccacca gcctgctggt ggtggtgctc
    42601 ggcgccagcg gctgggtgcg gcgggtgatg tccgcgctgc cgatgccgat cgtgatgggc
    42661 atggtggcgg gcgtcttcct gcgcttcggc ctcgacatcg tgcgcgcgct cgacagcgac
    42721 gtggcgatcg ccgcgccgat ggtcgccgcc ttcctgctgc tgtcggccag cccggccttg
    42781 gggcggcgca tgccgccggt catcggcgcg ctgctggtgg gcgcgctcgc gatcgcgctg
    42841 ctcggccgca tcgacggcgg cgcgctcggc ggcttcgcct tcgcccagcc cctggtgcag
    42901 gcgccggtgt ggtcggtggc ggcgctggtc gagctcgtcg tgccgctggc gatcaccgtg
    42961 ctggtggtgc agaacggcca gggcgtggcc gtcctcaaga acgccaggca cgacgcgccg
    43021 gtgaatacgg tggccttcgt gtccgggatc ggcgccttct tcagcgccat ggtcggtgcg
    43081 gtgagctcct gcctcaccgg accgaccaac gcgctgctga cctcgtccgg cgagcacggc
    43141 cgccagtaca ccgcggcgct gaccttcggc ctcttcggcg tgctgttcgg gctgatggcg
    43201 ccgaccttca ccgggttgat gctcgccgcc cccaaggagt acatcatggt gctcggcggg
    43261 ctggccatgc tgcgcgtgct gcagggcgcg ttcgttgcct ccttcggcgg cggccgcttc
    43321 accctgggcg cgctggtgag cctgctcgtg accgtcgccg acatcggcat gttcaacatc
    43381 ggcgccgcct tctggggcct ggtcgccggc ttcggcgtga gctggctgat ggaaaagcag
    43441 gacttcaccg cgctcgccaa tcgcacctga gcctccgggg caggcctgcc ccgtttccgc
    43501 cctgcgctgc gccggcccct tcccggggcc cggccggtac cctcccttca tgagcccctc
    43561 ctccctcgcg ccttccggta cccgtgccat cgtcgggcag ctgctccacc tggcgtggcc
    43621 gatcctgatc gcccagctgc tgtcgatgac catgatggtg gccgacaccg tgatcgccgg
    43681 gcgctacggc accgaggacc tcgccggcgt ggcgatcggc agcagctact acatctcggt
    43741 ggtgatgctg ctcaccggca cgctgcaggc gatctcgccg accatcgcgc accacgtcgg
    43801 cgccggccgc gaggaggcga tcgctcccgc gctgcagcag ggcttctggc tcgcgctgct
    43861 gctcaccggc cccgggatcg cgctgctgct caaccccggc ttcctgctcg aggcggcgag
    43921 cgtgccgccc gcggtcgccg ccaaggccgc cgactacctc gccgcgaccg ccttcggtct
    43981 gcccgcgctg ctgctctatc gcagcttcta cgccttcaac aacgcggtgg ggcggccgcg
    44041 cgtgctgatg gcgatcagcg cgatcaccat gtctacccac atcccgctcg cctgggcgct
    44101 caccaacggc gcgctcggct tcgcgccgat gggcggcacc ggctgcggcg tgtcgaccgc
    44161 gacggtgcac tggatcgcgc tcggctgcgg cctcgcctac ctggtcttca accccgcgta
    44221 caagccctac cgcctcttcc acgcctggca ggcgccgcgc gcgcaagcgc tcggccagct
    44281 gctgcggctc ggcctgccga tgggggtgtc gaccttcatc gacatcagct ccttcaccct
    44341 gatcgccatc ctcgccgccc gcctcggcac cgagaccgtg gccggacacc gcgtcatcgc
    44401 caacttcacc ggcatgatct acatgctgcc gctgtcgctg tcgattgcca ccatggtgct
    44461 ggtggggcag tcggcgggcg cgcaggactg gcgccgcgcg cgccgcaccg cacggctggg
    44521 gatgaatctc gccctcggct tctcgctgct ggtgggcgcg ctgctgtggg tgctgcgcga
    44581 gccgctggtg gccttctcgt ccgccgaccc ggcggtgcag gcggtcgcgc tcgggctggt
    44641 cgtgtggctg ctgctctacc agtgcttcga cgccttgcag accgtcgccg cccacgccct
    44701 gcgcggctac aaggtcacgc tgctgccgat gctggtgcac accttttgct tctggggcat
    44761 cgggctggcc ggcggctact ggctcagctt ccacgccccc tggcgcaccg aggccccgac
    44821 ggtggccggc ttctgggagg cctgcgtcct cgcgaccctc gccgccaccc tgctcttcgg
    44881 cgcgctgctg cgcgcggtct cccgccgcca cgtgcgcgaa gcggccgtgt agacacgccc
    44941 gcaggacctc ggaaccgcga cggtccatgt aggagcgccg gcaggcgcga atgcggcggt
    45001 cgagcctgca ccgccaaccc tccgaacgcc cattcgcgcc tgccggcgct cctacatggc
    45061 gtatcgcgcg cggagaagac gtcgcgtgcg agggggagcg cgtggggggg cgggagtctt
    45121 gcgggagggg cgtagcagaa aaggcagccg gttcatgtgc ccgcaccaga ccgcgcgcac
    45181 gacatcgggg ccgcgacggc tcatgtagga gcgccggcag gcgcgaatgc ggcggtggtg
    45241 cctgcaccgg cctcgctccg gcaggcgcgg tattcgcgcc ttgcgccgct cccacatggg
    45301 aaaaacgtga cgcgcgggcg gacgatttgg cgacaatgga ggctgtgact tcccgcaaca
    45361 tcccctggaa agaacgatga gcaagaacgc ccccctgtcg gatctgcgca agagctacga
    45421 gcaaggcacg ctggaagagc acgactcggc gaacgagccg ctgcagcagt tcgagacctg
    45481 gctgtcgcag gcgctcgagc gcgggcttcc cgagcccaac gcgatgaccg tggccacggt
    45541 cggcgaggat ggccgaccgt cgacccggcc ggtgctgatc aagggctgcg acgcgcgcgg
    45601 catcgtctgg tactcgaact accacagccg caagggccgc gagctggagg cgcgcccctt
    45661 cgccgcgctg cagttccact gggtcgagat ggagcgcgtc gtgcgcatcg agggccgcgt
    45721 cgagaaggtt gcggcggagg agtcggacgc ctacttcgcc acccgcccgc tcgcccaccg
    45781 catcggcgcc tgggcctcgc cgcagagcga ggtcatcgac gggcgcacca cgatcgtctc
    45841 gcgggcagcg gaatacgggc tgaaattcgg cctcaacccg ccgcgcccgc cgcactgggg
    45901 cggctaccgc ctgttgccgg actactggga gttctggcag ggccgcacgt cccgcctgca
    45961 cgaccgcatc gcctaccgac tgcagcccga cggcagctgg gcacggcaac ggctggcgcc
    46021 gtagcagggg ccgccgaggg gcgggcgttt ccgaaaccga cgcgcgtcgc ggggggcggc
    46081 ggcgtgttcg cgcctgccgg cgctcctaca tagacccgtc gcggcgtcat gtaggagcgg
    46141 cggcagccgc gaagcgggcg tttcggaaac cgacgtgcgt cgcgggcggg ggcggcgtgt
    46201 tcgcgcctgc cggcgctcct acacaaaccc gtcgcggtgc cctgtaggag cagcggcagc
    46261 cgcgaagcgg gcgtttcgga aaccgatgcg cgtcgcgggc ggcggcgccg tgttcgcgcc
    46321 tgccggcgct cctacataga cccgtcgcgg cgtcatgtag gagcagcggc agccgcgaag
    46381 cgggcgtttc ggaaaccgac gcgcgtcgcg ggcggcgccg tgttcgcgcc tgccggcgct
    46441 cctacatgaa cccgtcgcgg cgtcatgccg gcgcgaagcg gggatgcgat acgcgcggca
    46501 tgatgtgtgc gcacgcgccc cctgtaggag cgccggcagg cgcgaacacg gcgtgcaaat
    46561 atgcgctgcg cggattcctg gctcggcgcg ctcaggcggc gggagcgtcc tcgacgatca
    46621 ccacgtgcag ataccgcggc ccgtgcgcac cgagcaccag gctgccctcg atgtcggtgg
    46681 tgccgctggc gccggtgatg atgttgacgt tgcgcggcgg gcgctggccg gcggtggcgg
    46741 cggcgtagtc gtcgaggtag gccagcaccg tgctcgcgcg caccatcacc aggtggtgca
    46801 gaggcaggaa gttggcgagg atcggcgtct cggcatccga atggaagacc agcgagccgg
    46861 tctcggcgat gccccagcgc gcgaagccca cggccagggt ctcgtcgggg gcgacgcgct
    46921 cgtgcagctc gaagcctgcc cagtcgagcg cctgcagcac cgccgcgggc tggagcgcga
    46981 tcgcagcggg caggccgcgc gcttccacat agcgcgccac cgcggcgggc agcgcgcttg
    47041 cgtcggcgat gcgctcggcg gtggcggcga ccttgggggt gaccaggcgg gcgatgaagg
    47101 cctcgacgag gtcgtcggcg agcaggccgg ggcggatcgc gggcaggtct tcgagcaggg
    47161 cgtcggcctc gcggcgcagc gccgcggggt ccaccgtgcg gtggccgagg ccgccgcgca
    47221 ctgcgttgag aatggcttcg cgcgcgctca tcgggcgttc tcctgatcct tgaccatttc
    47281 catgaaggtg cgtttggccg gcgccgggaa ctcgcgatgc gcggtccacg cgcccagccc
    47341 gggcatcccc ttgacgaggc cgccgcggct gaagagccgc atcacccgca ccgcgatcgc
    47401 cgtgcccagg cggtacagcc gcgggtgcga ggcgacgaag gtgtggatgc ccagcccgaa
    47461 gcgcaccacc gagggctcca gcccctcgcg ccacgagcgg tcgcgccagc cgcgcagcag
    47521 cgtgggcagc gggatcgcca ccgggcacac ctcctggcac ttgccgttca tcgtgcacgc
    47581 gtgcggcagg tcgcgcgatt tctccaggcc gtcgaacacc ggggtgagca ccgcgcccat
    47641 cggccccggg taggtgccgc catagacgtg gccgccgagc tggcggaaga ccacgcagtg
    47701 gttcatgcag gcgccgcagc ggatgcagcg cagcatctcc ttcatgccct cgcgcagcat
    47761 gcggctgcgg ccgttgtcga ccagcacgat gtggaattct tccgggccgt cgcgatcgcc
    47821 cgcctgcttg gggccgcagt ggaaggtggt gtactgggtg acatccgcgc cggtggccga
    47881 gcgcaccagc aggcgcagca tggcgatggc gtgccccatg ctggggacga gcttctcgat
    47941 gccggcggtg acgatgtgca cccgcggcgg ggtggtggtg agttcggcgt tgccctcgtt
    48001 ggtcaccgtg caggtggcgc cggtgtcggc gaggaggaag ttcgcgcccg agatcgacac
    48061 gtcggcggtc aggaacttgt cgcgcagctc gcggcgcgcg ctgtcaacca tcgcctcgat
    48121 ggtctcttcc tggtgcggtg cgcggtgcag gcgcttgaac atctccgaca cctgctcgcg
    48181 cgtgcggtgc atcgacggcc acacgatgtg cgaggggcgg tcgccgccga gctgcacgat
    48241 gtgctcggcg aggtcggtct cgacgcgctc gatgccggcc tcgtcgagcg catgcggcag
    48301 gccgatctcc tcgcccagca tcgacttgac gcgggtgacg cgcttcgcgc cggcttcctt
    48361 gcacagacgc acgacgatct gcgcggcctc ctcggcggtc gcggcccagt acaccttggc
    48421 gcccgaggcg atcgcgttgc gttcgaactc gagcaggtag tgatcgaggt tggcgatcac
    48481 gtggtccttg atgcgcttgc cgcgctcgcg cgccgcctcg aactgcggga actggctcat
    48541 cgccaccgcg cgcttgcgct cggcggtgcc ggtggtacgg tcgatcgcga tcttgagcgt
    48601 ggggtcggcg agcgcgcgct cggcgcgcgc cttgaaggac agcgtggctt cttccatgac
    48661 tcagccctcc tcgccgatgg ccggcccgcc gcccatgccg gcgagcacct cggcggcgtg
    48721 gaaggcgcgc acgcccgagc ccttgcgctt gagcttgccc gccatgttca tcaggcagcc
    48781 gaggtcgccg ccaagcagca gctgcgcgcc gctgcgctcg atggcctcgg ccttctcgcc
    48841 gacgaccgcg ttggagatgg ccgcatactt gacgcagaag gtgccgccga agccgcagca
    48901 cacgtcgttg ccctcgagcg gcttcaaggt gagccccgcc accttgccga gcagcgcgcg
    48961 cggctggtca tgcacgccga gctcgcgcag gcccgagcag ctatcgtggt aggtgaagct
    49021 ggtgtcgagc cgcacgtccg tgggcgcgta gcccatcacg tcgaccagga agctcatcag
    49081 ctcgaagctg cgctcgccca ggcggcgcgc gcgctcggcc caggcggggt cgtcggcgag
    49141 cgcctcggcg tagtgcaccc tggtcatgcc gatacaggag cccgagggcg cgaccacgta
    49201 gtcgtagccc tcgaaggtct ggatgaagtg gcgcgccagc gtggccgcgt gcgcgatgtc
    49261 gccgctgttg aaggcgggct ggccgcagca ggtctgcgcc tgcggcacct cgacccggca
    49321 gccggcgtcg cgcagcagct tgagcgcggc gaagccgatg ctggggcgca tcgcgtccac
    49381 caggcaggtg gcgaagagcg cgacgcgcgg cgacacgggg cgcgagacgc ttcggggctc
    49441 gttcatgggg gtcttcctcc aggttgtccg ggtgatcgcc gattcttgtt cggggcgccg
    49501 gcaggtttct tccggggcag ccggacagga cccgcacccg gcaaaaccgc ctccgcgcca
    49561 catcggacag aatacgattg ttttcctggc gcggcgcaga ttcgggccag gcctacaggc
    49621 aaaccctgaa gagccctggc cttaccgccg gcaacgccgc gctgaactcc tgcgggggcg
    49681 gcccatgcat ctccggcttg cattcgcccc tccactgcgc cgatcatcgc gggcgccttt
    49741 ccatccagag acaccatgaa cacccaagcc atccaactgc cgccctcggg cgaagccgcc
    49801 gccatcctcc tgcccgatcc ggccaccgtc ttcctcgcgc gcgccgagcg tttcgacgcc
    49861 ctcgcgctgc atcacggcct gggcgagtgg ctcgcctttc tcggccgcct gtcgcgtgcc
    49921 cagcacgcgg cgctgcaggc cgccgcgccg gacatcgccc cgccggcgga agacgtgctc
    49981 gcgcgcgcgc gcaagcaccg catgccgccg atcagcgtgg cct
//
LOCUS       DAOTIN010000015        47609 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_780_length_47609_cov_9.392060, whole genome shotgun sequence.
ACCESSION   DAOTIN010000015 DAOTIN010000000
VERSION     DAOTIN010000015.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 47609)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 47609)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47609
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_780_length_47609_cov_9.392060"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1331)
                     /locus_tag="P5537_03995"
     CDS             complement(<1..1331)
                     /locus_tag="P5537_03995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HRV77238.1"
                     /translation="MTEFVIANMAPLMFASMVLFLLFGFPVAFALAANGILFGLVGIE
                     LGLLHGALFQALPERIFGIMANDTLLAVPFFTFMGLILERSGMAEDLLDTIGQLFGPI
                     RGGLAFAVIFVGALLAATTGVVAASVISMGLISLPIMLRYGYDHRLATGVIAASGTLA
                     QIIPPSLVLIVMADQLGRSVGDMYQGALLPGLVLTSMYVGYVALVAVFRPSFAPAMPP
                     EARTLREPDGASGLRSLALLTVVAVAGAWLFASQLYRADAPRDEVVVVSAMVGIGIAF
                     VAAMINRLFGIGLLSRMAERVTFVLIPPLGLIFLVLGTIFIGVATPTEGGAMGALGAV
                     LMALARRRLSLPLLKQAMDSTTKLSCFVIFILIGSSVFGLTFRGVNGDLWVEHLMTSL
                     PGGQTGFLVAVNLLVFVLAFFLDFFELAFIIVPLLAPVADKLGIDLKASSK"
     gene            complement(1328..1924)
                     /locus_tag="P5537_04000"
     CDS             complement(1328..1924)
                     /locus_tag="P5537_04000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease subunit"
                     /protein_id="HRV77239.1"
                     /translation="MSSLLRLSRLIDWINERVGRAVMWLVLVAVVISAGNALVRKLFN
                     TSSNALLEIQWYLFAAIFMLAAGYTFLRNEHVRIDILTSRLSPRGQNVVDILGIVFFL
                     LPMAVLILWLSWPIVMTSLASGEMSQNAGGLIRWPVKMLLPLGLGLLVLQALSELVKR
                     IAFLTGHGPNPLQKKSAGATTEDLVAAIKAQREGRAEP"
     gene            2044..2721
                     /locus_tag="P5537_04005"
     CDS             2044..2721
                     /locus_tag="P5537_04005"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HRV77240.1"
                     /translation="MMKTRNSPQSAHACRICLVRHGETAWNTERRLQGHIDIPLNPRG
                     LSQAEATARSLARAGERFAALYSSDLQRARQTADAVARAHQLAATHDARLRERHYGVL
                     QGLTFDEAALHQPQAWQHFKRRDPMVALDGGGESLAGLAARVHGALEEIAARHAGETV
                     VVVTHGGVLDIAHRLATGKPLEGARDFAIPNAALNWIEHTAGSWRLLAWADESHLTDA
                     LDELPGS"
     gene            2852..3934
                     /gene="dctP"
                     /locus_tag="P5537_04010"
     CDS             2852..3934
                     /gene="dctP"
                     /locus_tag="P5537_04010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein DctP"
                     /protein_id="HRV77241.1"
                     /translation="MERRKFLQGAGMAGILAAGTAPAIVHAQQQIRWRLASSFPKSLE
                     TVFGASEAFAKYVSEATGGKFVISVHPAGELVPAFGVVDAVQQGTIECAHTAPYYFFG
                     KDETFAFDCTIPFGMTSRAMSAWMFEGNGLKLMREFYAQFNIVNFPCGNTGAQMGGWF
                     RKEIKSVKDIEGLKMRIGGFGGRVLAKLGAVPQNIPAGEIYQSLEKGTIDAAEWIGPY
                     DDLKLGLHKVAQHYYFPAWWEGSTQFSVYINDKQWNSLSAEYKAIVEQASRAAHVTCQ
                     ARYDARNPGSLKQLIAEGAKLSRFPKDFMDAAFKASREVYAELNEKNANWKKVYPDYS
                     RFLADQVQWESVAEGNYAQYLASQKL"
     gene            4073..4675
                     /locus_tag="P5537_04015"
     CDS             4073..4675
                     /locus_tag="P5537_04015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease subunit"
                     /protein_id="HRV77242.1"
                     /translation="MDTLLRLSHGIDAVSRFFGKFIIWLVLAAALISAANAVARKAFN
                     IGSNAFLEIQWYLFGAVFLLGAGYTFLQNAHVRIDVLAGKLSMRTRMFIDIAGILVFL
                     LPMCWFMIQFAWPVVVGAYVSGEMSSNAGGLIRWPVYALVPLGFGLLALQAISELIKR
                     FAFLQGKAPNPLLHGAHESNEAHDAEHAQAHHDDAGEVRK"
     gene            4672..6495
                     /locus_tag="P5537_04020"
     CDS             4672..6495
                     /locus_tag="P5537_04020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HRV77243.1"
                     /translation="MIELFTAHAPELMFGSLLIFLLTGFPVAFALAACGLLFGFIGVE
                     IGLLSPSIFQALPLRVFGIIQNDTLLAIPFFTLMGLVLERSGMAEELLDTVGQVFGPI
                     RGGLALAVIFVGALLAATTGVVAAAVISMGLISLPIMLRYGYSPAIASGAITASGTLA
                     QIVPPSLVLIVIADQLGRSVGDMYKGAFVPAFMLIGLYVLFIIGLAIFKPAMVPALPP
                     EARTYREPDGSSGMRSLGVFTVFITAIAVAFGMHYGEILSALKGTEVKPAMDETIVVA
                     LTGGTLFAFVAALINKLTGLGLLSRITERVTFVLIPPLALIFLVLGTIFLGVATPTEG
                     GAMGAVGGMIMAFSRGKLDLAMLKHGLEATARLSCFVLFILIGSTIFSFTFTAVDGPI
                     WVEHLFDKLPGGEIGFLVFVNTVIFFLGFFIDFFEIAFILIPLLAPVADKLGIDLVWF
                     GVLLAMNLQTSFLTPPFGFALFYLRSVAPAKDYLDRITRKRVAGVKTTDIYAGSIPFV
                     LMQIVMVVALIAFPGLVTFTLDKKLEVDLDTIEIKIEGSGGGDGGGWGAPQSDSWGGG
                     AAPAEPVQGGDAPAEGGSAAPAGEAAPTGGNEGFGTQQRGW"
     gene            6629..7879
                     /gene="glyA"
                     /locus_tag="P5537_04025"
     CDS             6629..7879
                     /gene="glyA"
                     /locus_tag="P5537_04025"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HRV77244.1"
                     /translation="MFSSQDTLAKVDPELWSAIQAENKRQEDHIELIASENYVSHAVM
                     EAQGSQLTNKYAEGYPGKRYYGGCEHVDVAEQLAIDRLKALFGAEAANVQANSGSQAN
                     QAVLMAFAKPGDTIMGMSLAEGGHLTHGMPLNMSGKWFNVVAYGLNEKEEIDYDKMEA
                     MAREHKPKIIIAGASAYALRIDFERFAKIAKEVGAIFWVDMAHYAGLIAAGFYPNPVP
                     HADVVTSTTHKTLRGPRGGIILMKAEHEKALNSAIFPGLQGGPLMHVIAAKAVAFKEA
                     ASPEFRNYQEQVIANARVMARVLSEERGLRIVSGRTESHVFLVDLRNKKITGKAAEAV
                     LGSAHITVNKNSIPNDPEKPFTTSGIRLGSPAMTTRGFTEIEAEKIAHLIADVLDAPE
                     DAAVIERVRGQVAELCAKFPVYGK"
     gene            7922..8434
                     /gene="nrdR"
                     /locus_tag="P5537_04030"
     CDS             7922..8434
                     /gene="nrdR"
                     /locus_tag="P5537_04030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004376838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HRV77245.1"
                     /translation="MKCPFCGDPNTQVTDTRENEDGDVVRRRRRCVKCDKRFTTYERI
                     DLKMPHIVKRNGNRTEFDHAKLAGSMKLALRKRPVTIEAIDAAVDRIEARLLAMGEQE
                     VPSEKIGELVMKELKKLDKVAYIRFASVYRNFADVDEFAEVIREVQTRPRRGKADKGG
                     ADPGNDLFGG"
     gene            8415..9512
                     /gene="ribD"
                     /locus_tag="P5537_04035"
     CDS             8415..9512
                     /gene="ribD"
                     /locus_tag="P5537_04035"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HRV77246.1"
                     /translation="MTFSAADHAAMARALQLAARGLDTTSPNPRVGCVIVRDGATVGE
                     GWHARAGEPHAEIHALRAAGAAARGATAYVTLEPCSHFGRTPPCADALIEAGVARVIT
                     AMEDPNPLVAGRGLARLRASGIATAHGLLAEAAHELNIGFVSRMTRGRPWVRLKVAGT
                     LDGKSALDNGVSQWITGPAARRDGHRWRARACAILTGIGTVREDDPQLSVRDVPCSRQ
                     PLRILVDARLEVSVQARILQGDPILIATASTDEARIDALRAAGHELVCVPNAAGKVEL
                     GALLRLLGERGVNELHVEAGFKLNGSLMREGCVDELLIYLAPMLVGDTAQGLFNLPAL
                     TRLEGATRLDIRDLRRIGADLRLIARPLPQG"
     gene            complement(9557..10306)
                     /gene="moeB"
                     /locus_tag="P5537_04040"
     CDS             complement(9557..10306)
                     /gene="moeB"
                     /locus_tag="P5537_04040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004376841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008641 - ubiquitin-like modifier
                     activating enzyme activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-synthase adenylyltransferase MoeB"
                     /protein_id="HRV77247.1"
                     /translation="MNDDQLLRYSRHILLPEIDVEGQQALLDARALIVGAGGLGSPAA
                     MYLAAAGVGTVVLADHDTVDLTNLQRQIMHSADMVGLPKVASARATLHRLNPQTRLEP
                     IQARLEGEALEAEVARADVVLDCTDNFATRHAINRACVKHRKPLVSGAAIRFDGQVSV
                     FDLRKPDSGCYHCLFPEAEDIEEVRCAVMGVFAPIVGIVGTIQAAEALKVIIGCGRTL
                     DGRLLLLDGLSMEWRSVALGRDPGCAVCAGR"
     gene            complement(10327..10776)
                     /locus_tag="P5537_04045"
     CDS             complement(10327..10776)
                     /locus_tag="P5537_04045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77248.1"
                     /translation="MRRETAYKLAGRHHDRPLPGADIHKQRDIRFKPLPPGQVERAWR
                     ALQLLKGLQLERTDDPLCIVVRYSVLDYSLEALEDALREAGFALENSLYIKLVRALVY
                     FSEETQRHNLLSPERLIKQSNEVYIQAWDHHAHGDHDDTPLELREYK"
     gene            complement(10805..12265)
                     /locus_tag="P5537_04050"
     CDS             complement(10805..12265)
                     /locus_tag="P5537_04050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HRV77249.1"
                     /translation="MRSSKLKQFGLVMTGMVAGIMISLNFSANADRSVPPPLPVDELR
                     AYADVFNAIKQGYVEPVEDKKLITDSISGMLSGLDPHSAYLDAEAFKDLQVGTQGEFG
                     GLGIEVGMEDGFVKVISPIEDTPAFRAGVLAGDLIVKLDDTPVKGMSLNDAVKRMRGK
                     PRTDITLTIMRKGQPQPIVIKLTREVIKVQSVKSKVVEPGYAYLRIAQFQENTAASVV
                     EHLAKLAAQGPVQGLVLDLRNDPGGLLHGAVGVSAAFLPEETLVVSTDGRTEDAKREY
                     RAIQADYLRGTRDDFLRRLPAYARDVPMVVLVNAGSASASEIVAGALQDHKRAKVIGT
                     QTFGKGSVQTILPLNNNTAIKLTTARYYTPSGRSIQAKGIEPDIVVEETANGSSRRVR
                     EADLLGHLENDKGAGEAAKAATTAAGKGDGAAVEDESAEPVRFELAGENDHQLKQAIR
                     LLKGEDIAQAVQAAAAEAAGDKAAAVEAAQPAAAKQ"
     gene            complement(12310..13764)
                     /locus_tag="P5537_04055"
     CDS             complement(12310..13764)
                     /locus_tag="P5537_04055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HRV77250.1"
                     /translation="MSPRSLNPLLAGACVAAFVALAGVPRPALAQAGGEIAERRSDLD
                     ELKQRIRELQDEMARAEAERSTAQKALVESERAVSRAVRELGRIEGERRGAEKQLAVL
                     EGEQRETAARIDARRGELADWVRRHYVHGAADGVAPLLSARDPNQLARDAHYLEHLGR
                     ARLELIEGLRTDLAETRRRADEIVQRRDRLAALEREQRGRQQQLQTEQSRRKAALAEV
                     SRELKAKKTEVDALQQDEQRLGKLIETLARRARLAAAREAARREAEQREAERRAAAQR
                     EAERRQAAQREAERLAALAARARAEQEPRGETAARAAPEPAPRVEEPPPARVERAQRP
                     EPVVGEVRDAAGATPTGVRFNQLRGQLRFPVRGELVGRFGAPRAEGGTTWKGVFIRAG
                     DGAEVRAVAGGEVVFSDWLRGYGNLIIVDHGGDYLTIYGNNDALLKEEGERVGGGEPI
                     ASVGSAGVGNDSGLYFEIRHRGLPIDPMQWMRLN"
     gene            13954..14283
                     /locus_tag="P5537_04060"
     CDS             13954..14283
                     /locus_tag="P5537_04060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HRV77251.1"
                     /translation="MDKDAISTLIDKHEHIETAARALKAIAHPLRLKILCVLGGGEEC
                     VQDIVDAVGTSQSNISQHLAILRDKGVLQTRKDANRVYYRVGDERTLQLIVLMREVFC
                     APDADER"
     gene            14316..14732
                     /locus_tag="P5537_04065"
     CDS             14316..14732
                     /locus_tag="P5537_04065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004381874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HRV77252.1"
                     /translation="MEFLQQNWYWAALAAASGTWLMVELIRSRGDDTQLSPVEATLLV
                     NREDAIVIDVREQGEYAQGHIPNARHIPAGEIERRSKEMEKWKDHPVILCCATGARSN
                     SAAGALRKVGFNRIYNLRGGMMEWQKAGQPVSRKRK"
     gene            14735..15004
                     /gene="grxC"
                     /locus_tag="P5537_04070"
     CDS             14735..15004
                     /gene="grxC"
                     /locus_tag="P5537_04070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 3"
                     /protein_id="HRV77253.1"
                     /translation="MQPPIRMYATATCPYCIRAEQLLLDKGVTGLDKIRVDLDPARRE
                     EMMKLSGRRTVPQIFIGDYHVGGCDDLFALERAGKLDPLLRGEAA"
     gene            15104..15580
                     /gene="secB"
                     /locus_tag="P5537_04075"
     CDS             15104..15580
                     /gene="secB"
                     /locus_tag="P5537_04075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HRV77254.1"
                     /translation="MSENAQPVFSIEKLYVKDLSVEVPGAPQIFLERETPQVNVQLRT
                     EGQVVEEGVYEVTLTVTVNARIGEDRNLFLVEVAQAGIFQIRNLPEGELEPVMMIGCP
                     NILFPYAREAVSDAVTRAGFQPVLLSPVNFESLYQSQRQQAIEQAMQKANGEVPIQ"
     gene            15591..16088
                     /locus_tag="P5537_04080"
     CDS             15591..16088
                     /locus_tag="P5537_04080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HRV77255.1"
                     /translation="MKRARRPSPQSLPAPLGRALLNLAALVALGGAALPVAAQAIEYR
                     SAGAGALLRERPAAEAEPQFRLRPGTPVEVVVREDGWVRVRDPQGGLAWVEGSALTTR
                     RTVIVTAERAVIRRAPQESAAPAFEATRHVVLELLEPASEGWARVRHVEGFEGFVRAG
                     EVWGL"
     gene            16076..17077
                     /locus_tag="P5537_04085"
     CDS             16076..17077
                     /locus_tag="P5537_04085"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046167 - glycerol-3-phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HRV77256.1"
                     /translation="MGTVSRCRIAVFGAGAWGTALAQAFSASHDVVLWGRDRDQLDEI
                     GRLHENSRYLRGVRLRDALAVEPDFARAAVDADLHLVVTPLAGLRTTLRELRRLAPGR
                     ALLWACKGFEAGTGKLPHEIVAEECGAGAASGVLTGPSFAAEVARGLPAAIALAAHDA
                     DFARHWVGVLHQPRLRIYANTDLVGCEVGGAVKNVMAIAAGVSDGMGFGLNARAALIT
                     RGLAEIARLARALGARGETLMGLAGMGDLILTCTGDLSRNRRVGLALAEGKGLADILR
                     ELGHVAEGVSTAREVVGLARRHGVEMPICEAIDALLHHGLDARGAVERLLARDPRAE"
     gene            complement(17114..17590)
                     /locus_tag="P5537_04090"
     CDS             complement(17114..17590)
                     /locus_tag="P5537_04090"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004391211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HRV77257.1"
                     /translation="MFEIVLYQPEIPPNTGNVIRLAANTGCRLHLVAPLGFDLSDKQL
                     ARAGLDYHDLTCLTVHPDWAHCQAALAGRRMFAMSTRASRRHDRVDFQPGDALLFGPE
                     SRGLPEEVLRDFAPERRVRIPMRPTNRSVNLSNAVAVVVYEGWRQHGFAGAADQGD"
     assembly_gap    17851..17950
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(18106..18789)
                     /locus_tag="P5537_04095"
     CDS             complement(18106..18789)
                     /locus_tag="P5537_04095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HRV77258.1"
                     /translation="MDVLAPQDCFVCGATSGGEAVCSACADELPRRPPTACPQCGLPG
                     LDGGRCAACRRGAPAFDATRAVFDFAFPVDAMIHALKYRHQLAVGRFLGDALARCGAD
                     FGADSGAVDLVLPMPLHPRRLAERGFNQAVELARALARARELPLGLAVVRKLRDLPAQ
                     AGLDREARLRSPRGAFECVEDLNGRRVIVVDDVMTTGATLDELARCLKGKGASWVGNL
                     VVARTPSPY"
     gene            18899..19879
                     /gene="bioB"
                     /locus_tag="P5537_04100"
     CDS             18899..19879
                     /gene="bioB"
                     /locus_tag="P5537_04100"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004329059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004076 - biotin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HRV77259.1"
                     /translation="MTTTSATIERPAAPQSRHRWAVAEVEALFELPLLDLVFRAQQVH
                     RGHFDPQEVQRSTLLSIKTGGCSEDCGYCSQSARHDSGLARQRLLPIDEVLANARAAK
                     ARGASRFCMGAAWRGPKDQDLAPVLEMVREVKALGLQTCVTLGMLKEGQAEQLADAGL
                     DYYNHNLDTAPDFYGQVITTHTLQDRLDTLDKVRGAGINVCSGGIVGMGENRRQRAAL
                     IAQLANLPTPPESVPINNLVQVPGTPLAGAGALDPFEFVRTIAAARITMPASFVRLSA
                     GRGEMSDELQALCFMAGANSMFYGERLLTTDNPDADRDDRLFARLGLRAI"
     gene            19891..20832
                     /locus_tag="P5537_04105"
     CDS             19891..20832
                     /locus_tag="P5537_04105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HRV77260.1"
                     /translation="MDATRQGLTANEPPAAPGFTLDRGLLRRRFERAAPHYDAADALA
                     REVARRMDERLDYIRLSPQRVLDLGCGTGADLPRLAERFPAATLLAADFAPAMLARAG
                     VRLRPQGGGLLRRLIGGRPAAAPHFVADARALPLARASLGLVWSNLMLPALDDPLPAF
                     REVHRTLQVDGLFMFSTLGPDTLRELRAVLPAAAGERVHRFIDMHDLGDALVQAGFSD
                     PVMDMEMLTLTYADLDGLFADLRACGGNNAASTRPRGLSGRSGWEAARATYERLRRDG
                     RLPASFEIIQGHAWKAAPKTTEDGRAIVRFQPRPPAR"
     gene            20860..21510
                     /locus_tag="P5537_04110"
     CDS             20860..21510
                     /locus_tag="P5537_04110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine 5'-nucleotidase"
                     /protein_id="HRV77261.1"
                     /translation="MPTRPVWLFDLDNTLHNASPHIFPHINRSMTRYLEQHLGLGLDE
                     ANALRMQYWHRYGATMLGLMRHHGTDPDHFLVETHRFDRLHEMMVFERALRGMLRALP
                     GRRIVFSNAPRHYAEAVLEIMGVRRLFEDVVGIEDLDYHPKPGIRAYRSLLQRRRLNA
                     AQCIMLEDSAVNLRTAKRLGMRTVLVGGGLRTPAYVDLRIPNILALRRQLGRLQVR"
     gene            complement(21567..22076)
                     /locus_tag="P5537_04115"
     CDS             complement(21567..22076)
                     /locus_tag="P5537_04115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HRV77262.1"
                     /translation="MAHAAAARPVLRPLRADDLPAVLAIQRAAYGDGYQESAAVLGRK
                     LALAPQACWLAQSDGGVVGYVFAHPWGDAGAPPLHAPLQALPARAAHGFVHDLAVSPA
                     ARGLGVAAALFGRVRDWSDGAGHRGMRLVALADALPFWVRQGFAVVPGALPPGYGEGA
                     CLMERAVRD"
     gene            complement(22079..23095)
                     /gene="hemB"
                     /locus_tag="P5537_04120"
     CDS             complement(22079..23095)
                     /gene="hemB"
                     /locus_tag="P5537_04120"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0004655 - porphobilinogen synthase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0033014 - tetrapyrrole biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HRV77263.1"
                     /translation="MRPTGAFPSTRMRRMRRDEFSRRLMREHVLTANDLIYPVFVLDG
                     ADRSEAVPSMPGVERVSIDRLLRVAEEAVRLGVPALALFPVIDLAGKTPGAEEAWNPE
                     GLVPRTVQALKANFPELGVITDVALDPYTSHGQDGLIDPADPRGYVMNDETLEALAKQ
                     ALCHAQAGADVVAPSDMMDGRIGRIRAELDGAGHIHTRILAYSAKYASSFYGPFRDAV
                     GSAGNLGKGNKHTYQMDPGNSDEAIREVELDIAEGADMFMVKPGMPYLDIVRRVKQEL
                     QVPTYAYQVSGEYAMLKAAAANGWLDEKACALEALLSFKRAGADGILTYFALDAARWL
                     KAGA"
     gene            complement(23358..24044)
                     /gene="yihA"
                     /locus_tag="P5537_04125"
     CDS             complement(23358..24044)
                     /gene="yihA"
                     /locus_tag="P5537_04125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HRV77264.1"
                     /translation="MPLFRNATFEISIAKPSGLPPPSGAEIAFAGRSNAGKSSAINTL
                     AGHVRLAYVSKTPGRTQLINFFRLNNGALLVDLPGYGYAAVPEKIRRQWSGLIETYLR
                     TRESLIGLVLIMDSRHPLTPLDRNMIDWFAPSGRPMHVLLTKSDKLSRGAAAATLQEV
                     RRALEPLGPQVSVQLFSSLKKSGVEEVERVIGGWLVPPGAASEDAAGTPAAAGDALPA
                     AKTKAPDQGT"
     gene            24168..24797
                     /locus_tag="P5537_04130"
     CDS             24168..24797
                     /locus_tag="P5537_04130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="c-type cytochrome"
                     /protein_id="HRV77265.1"
                     /translation="MIKRSLLLSSLLLVAGGLQAQDQAPDLEKAKQTAETVCAACHSA
                     DGNSQLPANPKIAGQHEDYLFKQLREFKGWNGNPPVRENAIMGAMVAGLEEADMRGLA
                     KYFASNELKPEPAKSLGTIELGQKIWRAGIAEKGVPACAACHGPAGAGMPAQYPRLSG
                     QFAEYTEAQMKAFRDGVRLNDPNSMMRMIAIKMTDPEIKAVADYATGLR"
     gene            24990..27065
                     /locus_tag="P5537_04135"
     CDS             24990..27065
                     /locus_tag="P5537_04135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis protein ResB"
                     /protein_id="HRV77266.1"
                     /translation="MHSGIARALFELLSSMRFAISLLTILSIASVVGTVVRQNEPFNA
                     YLNQFGPFWFPVFEKLGLYSVYNAGWFLVILAFLVLSTTLCIVRQTAPMLREMRSFRE
                     RAREASLRSFAHRAILVPAVPEADTIERARAYLAHAGFASRVADNGEGTLLAARQGSA
                     GRIGYFLAHGAIVLICVGGLLDGNLPLRLQVWLGDKHTTTGNQLIADIPESARLGTGN
                     PSFRGDVFIPEGRTTSFAVLGLADGILLQELPFNVALDKFHIEHYENGMPKRFASDIR
                     VTDRSSGKTTQHTIEVNRPLTVDGITLYQSSFEDGGSRLTIKARSLLPGRPGVLREIE
                     GVVGESLAFADATAGFSYTLEFTDFKAFNVEDMRGSEGGQGDDAPRGMDKLQRHLGSG
                     AKGAEDRDMRNIGPSFTFKLRDPAGQAREFHNYMLPIEQGERWFLYTGLRDAQADAFR
                     YMRIPLDERGSVDSWFAIRDRLLDPAQRDTLVGRFAARSFPAGRGQDAMREALAQSAR
                     QTLGLFAEKGYETLGGFIEKSVPEAERGQAADVLVRILQGLAFEAWTLHRETTGEAAL
                     ELNPARATFLNDTIAAISDSHFYGAPAWLQLDAFEERHATVLQATRSPGMPLVYLGAL
                     LLVLGVFAMLYIRERRLFVLVKPNEALVAMSSNRRTLDVDETFRQHVEGLAAVLGAPV
                     PASDSREGA"
     gene            27065..28276
                     /gene="ccsB"
                     /locus_tag="P5537_04140"
     CDS             27065..28276
                     /gene="ccsB"
                     /locus_tag="P5537_04140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="c-type cytochrome biogenesis protein CcsB"
                     /protein_id="HRV77267.1"
                     /translation="MEIARPSPRTPSPGTPSRPQPPVLPPAALAPRTPLLRRLDALDW
                     LYALALALGAAFALYRYHTAMDVYDDLILVLHVPVLAVIGWHWKPFRAFLAAVALLAL
                     ASIALYQGDLARAEQTFLLKYLISSQTAIMWMSALIFIATGAYWLGLIGRSDFGERTG
                     SALTWIAATMGTTGLFVRWYESYLLGPEIGHIPISNLYEVFVLFTLMTALLYLYYEGR
                     YATRRMGAFVMIVISTAVAFLLWYTFTREAHEIQPLIPALQSYWMKVHVPTNFIGYGA
                     FAVSAMVGTAYLLAARGILASRLPALRVLEDVMYKAIAIGFAFFTIATILGALWAAEA
                     WGTYWQWDPKETWALIVWLNYATWLHMRLTKGLRGAVLAWWAVVGLLVTTFAFVGVNM
                     FLTGLHSYGAL"
     gene            28326..29573
                     /locus_tag="P5537_04145"
     CDS             28326..29573
                     /locus_tag="P5537_04145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030151 - molybdenum ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HRV77268.1"
                     /translation="MNPNPAGGDDRSFLAVDAARAAILGALAPISGRERVAVRAALGR
                     VLAEDVIAPCNVPAHDNSAMDGYAVRAADLRAEGESALAVVGTAFAGRPFSGMVGTGQ
                     AVRIMTGATIPQGADTIVVQEMARREHDRVFIPAGQKKGQNLRHAGEDLAEGGVAIAA
                     GKRCGPAELGLIASLGIAEVCVRRRLRVAVMSTGDEIASIGRPLGPGEVYDSNRYTLH
                     GVLTRLGCELLDLGVVPDRPEALEEAFREASQAADVIITSGGVSVGEADFIREMMNRM
                     GEVAFWKLAIKPGRPMAFGRIGDAVLFGLPGNPVAVMVTFYQFVQDALLQLMGVAPLP
                     APERFPVRAAFSMRKQPGRVEYLRGRLQRDGGTLAVALAGAQGSGVLSSMSEADCFVV
                     LPADCTAVQEGDTVLVQPFHGIV"
     gene            29621..30283
                     /gene="rpiA"
                     /locus_tag="P5537_04150"
     CDS             29621..30283
                     /gene="rpiA"
                     /locus_tag="P5537_04150"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HRV77269.1"
                     /translation="MTQDELKKAAAHAALDHVVEDSIVGVGTGSTVNHFIDALAGMRD
                     RIRGAVSSSEASTQRLRAHGIEVFDLNGIESLPVYVDGADEIDGGFAMIKGGGGALTR
                     EKIVAAVSARFVCICDASKKVDVLGRFPLPVEVIPMARSHVARELRAIGGEPRLREGF
                     VTDNGNLILDVHGLSISDPVATETRINQIVGVVTNGLFAVRGADVLLLAAPGGVQRLD
                     AR"
     gene            30373..31065
                     /gene="phoU"
                     /locus_tag="P5537_04155"
     CDS             30373..31065
                     /gene="phoU"
                     /locus_tag="P5537_04155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0051049 - regulation of transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HRV77270.1"
                     /translation="MTEHTLRQYDIELEEVRRGVLNMGGLAETQVVKAIEGLRSGQLD
                     LLDTVIEGDKPINLAQIELDDDCSHIIAKRQPAAGDLRLVLSVIKIASDLERIGDEAK
                     KIAKAARRLHSAEAPFVPRVGLTQAVELALELLRASLDAFARVNPEGIEDLRRKDAEI
                     DAGFKGVMRQLITYMMEDPRTISSCLEMLFIAKAIERVGDHAMNIAEHVVFVARGEDV
                     RFENTQAKLGKG"
     gene            complement(31133..31405)
                     /locus_tag="P5537_04160"
     CDS             complement(31133..31405)
                     /locus_tag="P5537_04160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidative damage protection protein"
                     /protein_id="HRV77271.1"
                     /translation="MARMVNCVKLGREAEGLDLPPVPGALGKRIFENVSKEAWQQWVK
                     YQTMLINENRLNLMDARARKYLAEQMEKHFFEGGADQIAGYVPPQP"
     gene            complement(31408..32826)
                     /locus_tag="P5537_04165"
     CDS             complement(31408..32826)
                     /locus_tag="P5537_04165"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HRV77272.1"
                     /translation="MSACPAPGAREDAELLAEIALGVRSVEAVFLPGLALRWISPSIE
                     ALTGFSAQDCVGAADPFELLVFEDDRVFCRRMAQRVEAEGIEQAFELRLRTRDDHTVW
                     VQTHWRPRAGGGVRLSAEHIQARKETEFTLLETVAELRRQEALRELYLVRSNDERQRL
                     AALLNLIRIGILFIDQDRRVLYHNRAMLEIWGYPPETLLVGCRDAVLKERAPVVLSDP
                     AAYLAHIDRTVRGKQAISDEYEFHFTDGRIATDRSAVVAAEEAGRRIGRLWIYEDVTV
                     ARRTSMRLVELAERDELTGLYNRRRFHEELGRMLADAERRGSRLGLLAFDLDGFKPIN
                     DSFGHQAGDEVLVRLAVELGRTVRRNETLFRVGGDEFALLVPEGSAEGLRELAHRLVE
                     TVAAMRFVFDGREAAVTASVGIARFPDNAREGEALVAAADEALYRAKSEGRNRAAVSG
                     RRGGESARMPSSNPDEPASRED"
     gene            complement(32823..34139)
                     /gene="argA"
                     /locus_tag="P5537_04170"
     CDS             complement(32823..34139)
                     /gene="argA"
                     /locus_tag="P5537_04170"
                     /EC_number="2.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004042 - acetyl-CoA:L-glutamate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino-acid N-acetyltransferase"
                     /protein_id="HRV77273.1"
                     /translation="MDDATAQFVAWVRGAAPYIHAFRGRTFVVGFGGEVAAGKRAQSL
                     AYDCNLLAALGIRLVLVHGARPQIDAEQARRGLEPRFHHGLRVTDPEALECVKSAMAV
                     TRFEVEALLSQGLPNTPMAGSYIRVTGGNFITARPVGVVDGVDYQYTGAVRKIIAEEI
                     NADLDQQNVVLITPLGVSPAGEIFNLAMEEVAEAVAVALKAEKLIYLCDAPGLLGEDG
                     QLVESVTADEAQSKLDTGEGLTEDLHLFLPCAIRAVRKGVARCHLIDHDLDGGLLLEF
                     FTHAGVGTVVSRDPLFRLREATVEDVAALVALISPMEADGTLVRRGRELLEQEIERFT
                     VVEHDGVLVGCAALYPFSEDNAAELACLAVTPEYRRAGLGDQLLKRIERRARVQRLER
                     LFVLTTRTAHWFRERGFSEIGPEALPRQKRELYNFQRRSKVFVKPL"
     gene            complement(34313..34912)
                     /locus_tag="P5537_04175"
     CDS             complement(34313..34912)
                     /locus_tag="P5537_04175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002945472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemerythrin domain-containing protein"
                     /protein_id="HRV77274.1"
                     /translation="MDAMRILMDEHQSLAAIIHAIRHMIGEIEAGRLQPDHKLLEAMV
                     HYLEAYPEKRHHPKEDAFLFGPLRARTHDADAALDRLEAEHADADARIAVLEAAVQGY
                     AHDPAGGFAAFKAAFNDYAAFYRNHMMTEEREVLPQIRKHFTAEDWARANAGFVADDP
                     LSGTRATARAGEEDFAQIFSRLVAAAPAPIGLGAGPYKG"
     gene            complement(34953..35747)
                     /locus_tag="P5537_04180"
     CDS             complement(34953..35747)
                     /locus_tag="P5537_04180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002945475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV77275.1"
                     /translation="MTQQKQDSAAASNAGAKNPVLEVRDLCVSYGKVEALTDASLTVG
                     EGQIVTVIGPNGAGKTTMLSAIMGVLGSRGQVAFDGRVEGVPEVERMVARGMTLVPEK
                     RELFGEMSVEDNLVLGAFQRYRMGKRDHAQTLEEVYALFPRLKERRDQAAGTMSGGER
                     QMLAVGRALMAKPKLLMLDEPSLGLAPLIVREIFRIIGELRRRGVSILLVEQNARAAL
                     QVADYAYVLETGQIAMQGPAHELADDPRVIEAYLGLGGKHQAMLST"
     gene            complement(35762..37555)
                     /locus_tag="P5537_04185"
     CDS             complement(35762..37555)
                     /locus_tag="P5537_04185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     ATP-binding protein/permease"
                     /protein_id="HRV77276.1"
                     /translation="MRADRLVLGAFVALLLLVPAILSPYYVTLLNYIGLYAMVALGLV
                     LLTGVGGLTSFGQAAFVGLGAYTTAALTTATDLPGWLAWAGASPWLTLLVGLLLTAAV
                     AVLIGSLTLKLSGHFLPLGTIAWGISLYFLFGTMESLGGHTGISGIPAIALFGWTLDE
                     GGEIYYLIWAFLLVAMLTTHNLLDSREGRAIRALKGGRVMAEAMGVDTSRSRMVIFVI
                     AALLACASGWLYAHMQRFVNPTPFGVHIGIEYLFMAVVGGAGYVWGAIVGAGVITVLK
                     QWLQNWLPSLLGATGNFETIVFGLLMVLVLHRAREGLWPILRKLVPVRTVRRTLDADA
                     EPLPRRTLPKAGELILEAKEVTRRFGGLVANNNMSLEVRAGEILALIGPNGAGKSTMF
                     NQISGVDTPTSGEVLFLGKPVAGHDSREIARMGMSRTFQHVKLLPTMSVLENVAIGAH
                     LRSNKGVLSSAWRLDRAEEARILKEAARQIERVGLAEHMYEEAGSLALGQQRILEIAR
                     ALCADPCLLLLDEPAAGLRFKEKEALGELLKKLRAEGMATLIVEHDMDFVMSLVDRVV
                     VMEFGQKIAEGLPDEIQQNPAVLEAYLGGVE"
     gene            complement(37552..38589)
                     /locus_tag="P5537_04190"
     CDS             complement(37552..38589)
                     /locus_tag="P5537_04190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HRV77277.1"
                     /translation="MDMAIALILSQDGITNGAIYALLALALVLVFAVTRVIFIQQGEF
                     VAYGALTLAMMQSGVLPATVWMLVVMGALVTVLDGGLALKAGQGRRAAGVAGWNLGYP
                     LALAAVVGGLAVDALPLALQVLLTLAIVVPMGPMMYRLMYQPIASAPVLVLLIVSVAL
                     HIAMVGLGLLFFGAEGQRTPAFSEFSLELGPLMVSAQTLWVVAVSVLLIVALYQFFGR
                     TLYGKALRATAINRVGAQLMGISPTLAGKLTFFLAAFIGALSGVLIAPITTIYYDTGF
                     LIGLKGFVAAIIGGLASYPLAAAGALAVGLLEAFASFWASAYKEVIVFTLIIPVLLWR
                     SLTSHHVEEEE"
     gene            complement(38704..39852)
                     /locus_tag="P5537_04195"
     CDS             complement(38704..39852)
                     /locus_tag="P5537_04195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HRV77278.1"
                     /translation="MKLRNTLLAALGLAFAATAAHADIKVGVVLSATGPAASLGIPEK
                     NTIGLLPTTIGGEKVSYIVLDDASDTTTAVKNARKLTVEDGVDVIIGSTTSPASLAMV
                     DVAAETKTPMISMAASARIVAPMDDKKRWVFKTPQNDQQMASAIIGHMSANNVRKVSF
                     IGFANAYGEGWYEQFKKLAEAKGIEVAASERFNPADTSVTGQALKLMSVKPDAVFIAG
                     SGTPAALPQKTLRERGYKGPIYQTHGVANNDFLRICGKDCEGTLLPVGPVQMARSLPD
                     SHPVKASALAYVEKYEAANGAGSVSSFGAYAWDAGVLLEAAVPAALKVAKPGSAEFRA
                     ALRDALEGVKEVAGATGIYSMSAEDHLGLDDRSRVMIEIRNGTWSLLK"
     gene            complement(40052..40867)
                     /locus_tag="P5537_04200"
     CDS             complement(40052..40867)
                     /locus_tag="P5537_04200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HRV77279.1"
                     /translation="MSDEIDGKHGVQSLEVGMSILRAMVAGKRSMMLKDIAQAADMPP
                     SKAHRYLVSLIRSGLVEQDRLTSRYDLGPFALNLGLVALDRVDRIRLGLNAISELRDL
                     TNETVALAVWSDRGPVIVRWERPRRPITVNVLTGTSLSLLSSAAGRVFAAWLPEAQTD
                     ALLRAEIESGRVPAGIATLGDARRQLAEVRAQGLAVISSGYFARGVEAAAGPVFNFKN
                     EINMSIALVGVEGTLDLRPQSPVLLALRDACDALSLRLGATAIPGVEPGSQAG"
     gene            40948..41565
                     /gene="paaY"
                     /locus_tag="P5537_04205"
     CDS             40948..41565
                     /gene="paaY"
                     /locus_tag="P5537_04205"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetic acid degradation protein PaaY"
                     /protein_id="HRV77280.1"
                     /translation="MKQLKVYAIDGIVPVVDPTAYVHPSAVLIGDVIVGPDCYVGPCA
                     CLRGDFGRLILERGSNLQDTCVMHGFPGTDTVVEEDGHIGHGAVLHGCRVGRNALVGM
                     NTVIMDNAVIGESSIVAAAAFVKAGVEIPPRMLVAGVPAKAIRPLTDEEMRWKSAGTA
                     TYQDLTRRSLATMEETVPLTAVETDRKRIHMPDVVPLVELRRREA"
     gene            complement(41653..42603)
                     /gene="paaX"
                     /locus_tag="P5537_04210"
     CDS             complement(41653..42603)
                     /gene="paaX"
                     /locus_tag="P5537_04210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetic acid degradation operon negative
                     regulatory protein PaaX"
                     /protein_id="HRV77281.1"
                     /translation="MTTPIQDRLDAFRKQDRVQAGSLIISVFGDAVLPRGGRIWLGSL
                     IRLLEPLGLNERLVRTSVFRLARDEWLVSEPCGRRTDYKLTPSGLQRIEEASRRIYAS
                     SAQGWDRRWRLILAVGELAARDRERLRRALFWQGFGMLDGDCFVHPSADLIVAFDALV
                     GEGLGELLPQLKPLMAADAALGAAASDADLVHAAWNLERLAQMYRDFVDRYQPVLAQL
                     RDGAGDCGDESAFLLRMLLIHDYRRLLLRDPGLPDVLLASDWPGQRARLLCRELYRRL
                     LASSERHLDAHLQLADGHAPEASSSLLRRFQDADPLRGAR"
     gene            43071..44738
                     /gene="paaN"
                     /locus_tag="P5537_04215"
     CDS             43071..44738
                     /gene="paaN"
                     /locus_tag="P5537_04215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetic acid degradation protein PaaN"
                     /protein_id="HRV77282.1"
                     /translation="MPHPLLDKHRATLDSALNAIATRGYWSPFPEMPSPKLYGETAPD
                     EGKRAFEAHLGKQFELGQPGQTGWHGGESSPYGVELGVSYPVCDPDVLIAAALEAMKG
                     WQAVGADGRTGICLEILERLNKQSFEIAHAVMMTTGQGWMMAFQAGGPHAQDRGLEAV
                     TYAWREQSFVPSEATWEKPQGKNPPLVMKKNYQIVGRGVGLVIGCGTFPTWNTYPGLF
                     AALSTGNAVIIKAHSNAILPAAITVRTIRAVLAENGIDPNLVSLCVATQRSVTQALAT
                     HPAVQSVDFTGSNVFGQWLIDNCRQAQVYAELAGVNNIVIDSTDAYKAMLGNLAFTLS
                     LYSGQMCTTSQAIFVPAGGIDTEDGHKSYDEVCADLARAVERFLSKPEVAHAVLGAIQ
                     SADTAERIDIANSGALGKVVLASQKLDNPEFPGAKVRTPVLLACDAADEKAYMEERFG
                     PISFIVKVADTAAGIALSERVVRTHGALTVGLYSTKQDVIDAMTEATWRGKVALSINL
                     TGGVFVNQSAAFSDYHGTGGNPSANASYSDSAFVANRFRVVQRRHHV"
     gene            44749..45543
                     /gene="paaG"
                     /locus_tag="P5537_04220"
     CDS             44749..45543
                     /gene="paaG"
                     /locus_tag="P5537_04220"
                     /EC_number="5.3.3.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA
                     isomerase PaaG"
                     /protein_id="HRV77283.1"
                     /translation="MEYANIQFAVEAGIARLTLNRPDKLNSFTGEMHAELRDALDRVQ
                     ADKAARVLVLTGAGRAFCAGQDLADPDMATVGGKMPDIGNVVENNYKPLVLRLQNLRV
                     PTIAAVNGIAAGAGASVALACDLVVATKSASFLQAFSKIGLVPDTGGTWFLPQRVGMA
                     RAMGLAMLADKLPAEKAADWGLIWAAYDDAEFGARVDALAAQLAAMPTKALVRTRQAM
                     HAAAGHTLEQQLSFEGGFMRELGWSPDYAEGVAAFMEKRAPKFTGE"
     gene            45540..47099
                     /gene="paaC"
                     /locus_tag="P5537_04225"
     CDS             45540..47099
                     /gene="paaC"
                     /locus_tag="P5537_04225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008691 - 3-hydroxybutyryl-CoA
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA];
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-CoA dehydrogenase PaaC"
                     /protein_id="HRV77284.1"
                     /translation="MSVTDIETSTPAVQPLPPSAVIAVVGTGAMGAGIAQVAAAAGHV
                     VKLLDNRPGAAAKAIEGIRAQFGKLADKGKLSAEAAQAAGTRLVAVEQLAELADAALV
                     VEAIVENLEAKQKLYRDLEDIVGADCIFGTNTSSISVTSIGAALQRPERLAGLHFFNP
                     APLMKLVEIVAGLATARSVADTLFATAAAWGKTPVHARSTPGFIVNRVARPYYAEALR
                     ILNEGGSDCATLDAILRDAGGFRMGPFELMDMIGHDVNFAVTRSVWNAFYNDPRFTPS
                     LIQQELVDAGFYGRKSGRGFYDYREGAARPAPHVAVAQNAPDEIVLHGHSAAVHALAD
                     RLFERNIPHTWGEANDGRIAETGGAVIFVTDGRTATQRAAEMGIANVVLIDLALDYAT
                     APRIAVGAAINCFAPAVGAAISLLQAAGFEVCRLGDTPGLAVMRTVAMLANEAADAVS
                     QGVCDAAGADAAMKLGVNYPRGPLEWADRVGLPVIGAVLSNLARFYGEDRYRVSPLIQ
                     QRVFAGKKIHD"
     gene            47092..47559
                     /gene="paaI"
                     /locus_tag="P5537_04230"
     CDS             47092..47559
                     /gene="paaI"
                     /locus_tag="P5537_04230"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyphenylacetyl-CoA thioesterase PaaI"
                     /protein_id="HRV77285.1"
                     /translation="MTDVQPVPTDPQALAEAVTAAMWSRDRTAQSLGMRIESVGPGRA
                     TVRMTVRGDMVNGHHICHGGLIFTLADTAFAYACNAYNRNTVASGCNIDFVATGREGD
                     TLQAEAVERTLAGRTGVYDVTVRDSAGNTIALFRGKSYRISGEVIAGLAAENA"
BASE COUNT         7489 a        17161 c        15851 g         7008 t
ORIGIN      
        1 tacttcgaac tcgccttcag gtcgatgccg agcttgtcgg ccaccggcgc gagcaggggc
       61 acgatgatga aggccagttc gaagaagtcg aggaagaagg cgagcacgaa aaccagcagg
      121 ttcaccgcga ccaggaagcc ggtctgcccg ccgggcagcg aggtcatcag gtgctcgacc
      181 cagaggtcgc cgttgacgcc gcggaaggtg aggccgaaca cgctcgagcc gatcaggatg
      241 aagatcacga agcaggacag cttggtggtc gagtccatcg cctgcttgag cagcggcagc
      301 gacaggcggc gacgcgcgag cgccatcagc accgcgccga gcgcacccat ggcgccgccc
      361 tcggtcggcg tggcgacgcc gatgaagatg gtgcccagca cgaggaagat cagcccgagc
      421 ggcgggatca gcacgaaggt cacgcgctcg gccatgcgcg acagcaggcc gatgccgaac
      481 agccggttga tcatcgccgc cacgaaggcg atgccgatac cgaccatggc cgacaccacc
      541 accacctcgt cgcgcggcgc atcggcacga tagagctggc tggcgaagag ccaggcgccg
      601 gccaccgcga ccacggtcag cagggccagc gagcgcagcc cgctggcgcc atcgggctcg
      661 cgcagcgtgc gcgcctcggg cggcatcgcc ggcgcgaagg acggccggaa gaccgcgacc
      721 agcgcgacgt agccgacgta catgctggtg agcaccagac ccggcagcag cgcaccctgg
      781 tacatgtcgc cgacgctgcg gccgagctgg tcggccatca cgatcagcac cagcgagggc
      841 gggatgatct gcgccagcgt gccggaggcg gcgatcacgc cggtggccag gcggtggtcg
      901 tagccgtagc gcagcatgat cggcagcgag atcaggccca tcgagatcac cgaggccgcc
      961 accacgccgg tggtcgcggc cagcagcgcg ccgacgaaga tcaccgcgaa ggcgagaccg
     1021 ccgcggatcg gcccgaagag ctggccgatg gtgtcgagca ggtcctcggc catgccgctg
     1081 cgctccagga tcaggcccat gaaggtgaag aagggcaccg cgagcagggt gtcgttggcc
     1141 atgatgccga agatgcgctc cggcagggcc tggaagagcg cgccgtggag caggccgagc
     1201 tcgatgccga cgaggccgaa gaggatgccg ttggccgcga gcgcgaacgc caccgggaag
     1261 ccgaacagca ggaacagcac catggacgcg aacatcagcg gcgccatgtt ggcgatgacg
     1321 aactcggtca tggctcggcc ctcccctcgc gctgcgcctt gatcgccgcc accaggtcct
     1381 cggtcgtcgc gcccgcggac ttcttctgca gcgggttggg cccgtgtccg gtcaggaagg
     1441 cgatgcgctt gaccagctcg gagagggcct gcagcaccag caggccgagt ccgagcggaa
     1501 gcagcatctt caccggccag cggatcaggc cgccggcgtt ctgcgacatc tcgcccgagg
     1561 ccagcgaggt catcacgatc ggccacgaca gccacaggat cagcacggcc atcggcaaca
     1621 gaaagaacac gatgccgagg atgtcgacga cgttctgccc gcgcggcgat agccggctgg
     1681 tgaggatgtc gatgcgcacg tgctcgttgc gcaggaaggt gtagcccgcg gcgagcatga
     1741 agatcgcggc gaacaggtac cactggatct cgagcagggc gttggaactt gtgttaaaca
     1801 gcttgcggac gagcgcgttg ccggcgctga tcaccacggc gaccagcacc agccacatca
     1861 ccgcgcgtcc gacccgttca ttgatccagt cgatcaagcg ggataagcgc agcagagagg
     1921 acacgggaag actccggaaa ccggggcggc atgccgcccg ggtgccgctt tgcaagccgg
     1981 caggcctgaa aaatctcgat tatcccacaa gggccgtcct tgccgggcgg ctgcttgccc
     2041 ataatgatga aaacacgaaa ctcgccacaa tcagcacacg cctgcaggat ctgcctcgtc
     2101 cgccacggcg aaaccgcctg gaataccgag cgccgcctgc agggccacat cgacattccg
     2161 ctgaacccgc gcggcctgtc ccaggccgag gccaccgcac gcagcctcgc gcgcgccggc
     2221 gaacgcttcg ccgcgctcta cagcagcgac ctgcagcgtg cacgccagac cgccgacgcg
     2281 gtcgcgcgcg cgcaccagct cgccgccacc cacgacgcgc gcctgcgcga gcgccactac
     2341 ggcgtgctcc aggggctgac cttcgatgag gccgcgctcc accagccgca agcctggcag
     2401 cacttcaagc ggcgcgatcc gatggtggcg ctggacggcg gcggcgagag cctggccggc
     2461 ctcgctgcgc gcgtgcatgg cgcgctcgag gagattgccg cgcgccatgc cggcgagacg
     2521 gtggtggtgg tgacccatgg cggcgtgctc gacatcgccc accgcctggc caccggcaag
     2581 ccgctcgagg gggctcgcga cttcgcgatc ccgaacgcgg cgctcaactg gatcgaacac
     2641 acggcaggga gctggcggtt gctggcatgg gccgacgaaa gccacctcac cgacgcgctg
     2701 gacgagctgc cggggagttg atgcgcaatg catctaaaat gacaaagtgg cgcgccatta
     2761 gggttttccg tggattacag cccggtatcg ggtcttccta taatcgcatt gatggtttcg
     2821 atcacacacc tcacgcgata aaggagacac cgtggaacgt cgtaaatttc tgcagggcgc
     2881 cggcatggcc ggcattctcg ctgccggcac cgccccggcc atcgtccacg cccagcagca
     2941 gatccgctgg cgcctcgcat ccagcttccc gaaatcgctc gagacggttt tcggcgcgag
     3001 cgaggcattc gccaagtacg tctccgaggc caccggcggc aagttcgtga tctcggtgca
     3061 cccggcgggc gaactcgtgc ccgcattcgg cgtggtcgac gccgttcagc agggcaccat
     3121 cgagtgcgcc cacaccgccc cctactactt cttcggcaag gacgagacct tcgccttcga
     3181 ctgcacgatc cccttcggca tgacctcgcg cgcgatgagc gcgtggatgt tcgagggcaa
     3241 cggcctcaag ctgatgcgcg agttctacgc ccagttcaac atcgtgaact tcccctgcgg
     3301 caacaccggc gcccaaatgg gtggctggtt ccgcaaggag atcaagtcgg tcaaggacat
     3361 cgagggcctg aagatgcgca tcggcggctt cggcggccgc gtgctcgcca agctcggcgc
     3421 ggtgccgcag aacatccccg ccggcgagat ctaccagtcg ctggagaagg gcacgatcga
     3481 cgcagccgaa tggatcggcc cctatgacga cctcaagctc ggcctgcaca aggtggcgca
     3541 gcactactac ttcccggcgt ggtgggaagg cagcacgcag ttctcggtgt acatcaacga
     3601 caagcagtgg aacagcctgt cggccgagta caaggcgatc gtcgagcagg cctcccgcgc
     3661 cgcccacgtc acctgtcagg cgcgctacga cgcccgcaac cccggctcgc tcaagcagct
     3721 gatcgccgaa ggcgccaagc tgtcgcgctt cccgaaggac ttcatggacg ccgcattcaa
     3781 ggcctcgcgc gaggtctatg ccgagctcaa cgagaagaac gcgaactgga agaaggttta
     3841 ccccgactac agccgcttcc tggccgacca ggtgcagtgg gagtccgtgg ccgaaggcaa
     3901 ctacgcgcag tacctcgcat cgcagaagct gtaagcggtc cgcagcgggc ggggccaccc
     3961 ctgcccgccg gtcgttcccg tttcacattc ttcgcacgca gatttcctcc cgccgagcgc
     4021 gccacccgcc ctgctcggcg tttttgtgca cgcaaggttc aaggcgaccc ccatggacac
     4081 cctgctccgc ttgtcacacg gcatcgacgc cgtgagccga ttcttcggca agttcatcat
     4141 ctggctcgtc ctcgccgcgg cgctcatcag tgcggcaaat gcagtcgcgc gcaaggcctt
     4201 caacatcggc tcgaacgcct tcctcgagat ccagtggtat ctcttcggcg cggtgttcct
     4261 gctcggcgcc ggctacacct tcctgcagaa cgcccacgtc cgcatcgacg tgctcgcggg
     4321 caagctgtcg atgcgcacgc gcatgttcat cgacatcgcc ggcatcctcg tcttcctgct
     4381 gccgatgtgc tggttcatga tccagttcgc ctggccggtg gtggtcggcg cctatgtctc
     4441 tggcgagatg tcgtccaacg ccggcgggct gatccgctgg ccggtgtatg cgctggtgcc
     4501 gctcggattc gggctgctgg cgctgcaggc gatctcggag ctgatcaagc gtttcgcctt
     4561 cctgcagggc aaggcgccca acccgctgct gcacggcgcg cacgagagca acgaggcgca
     4621 cgacgccgaa cacgcccaag cccatcatga cgacgccggc gaggtgcgca aatgatcgaa
     4681 ctgttcaccg cccacgcccc cgagctgatg ttcgggtcgc tgctgatctt cctgctcacc
     4741 ggcttcccgg tcgccttcgc gctcgccgcc tgcggcctgc tgttcggctt catcggcgtc
     4801 gagatcggct tgttgtcgcc cagcatcttc caggcgctgc cgctacgcgt cttcggcatc
     4861 atccagaacg acaccctgct cgcgatcccc ttcttcacgc tgatgggcct ggtgctcgag
     4921 cgctccggca tggccgagga gctgctcgac acggtcggcc aggtgttcgg gccgatccgc
     4981 ggcggcctcg cgctcgcggt gatcttcgtc ggcgcgctgc tggcggcaac caccggcgtg
     5041 gtcgcggccg cggtcatctc gatgggcctg atctcgctgc cgatcatgct gcgctacggc
     5101 tacagcccgg cgatcgccag cggcgcaatc accgcctcgg gcacgctcgc gcagatcgtg
     5161 ccgccctcgc tggtgctgat cgtcatcgcc gaccagcttg gccgcagcgt cggcgacatg
     5221 tacaagggcg cgttcgtccc ggccttcatg ctcatcggcc tgtacgtgct gttcatcatc
     5281 ggcctggcga tcttcaagcc cgcgatggtg cccgccctgc cgcccgaggc gcgcacctac
     5341 cgcgagccgg acggcagctc gggcatgcgc tcgctcggcg tgttcaccgt tttcatcacc
     5401 gcgatcgcgg tcgccttcgg catgcactac ggcgagatcc tgagcgcgct caagggcacc
     5461 gaggtcaagc cggcgatgga cgagaccatc gtcgtggcgc tcaccggcgg cacgctgttt
     5521 gcgttcgtcg ccgcgctgat caacaagctc accggcctcg gcctgctgtc gcgcatcacc
     5581 gagcgcgtga ccttcgtgct gatcccgccg ctggcgctga tcttcctggt gctgggcacg
     5641 atcttcctcg gcgtcgccac accgaccgag ggcggcgcga tgggggcggt gggtggcatg
     5701 atcatggcct tctcgcgcgg caagctcgac ctggcgatgc tcaagcacgg cctcgaggcc
     5761 accgcccggc tgtcgtgctt cgtgctcttc atcctgatcg gctcgaccat cttcagcttc
     5821 accttcaccg cggtcgacgg tccgatctgg gtcgagcacc tgttcgacaa gctgcccggc
     5881 ggcgagatcg gcttcctggt gttcgtgaac acggtgatct tcttcctcgg cttcttcatc
     5941 gacttcttcg agatcgcctt catcctgatc ccgctgctgg cgccggtggc cgacaagctg
     6001 ggcatcgacc tcgtgtggtt cggcgtgctg ctggcgatga acctgcagac ctccttcctc
     6061 accccgccgt tcggcttcgc cctgttctac ctgcgcagcg tggcgccggc caaggactac
     6121 ctcgaccgca tcaccaggaa gcgcgtcgcc ggcgtgaaga cgaccgacat ctacgccggc
     6181 tcgatcccct tcgtgctgat gcagatcgtc atggtggtgg cgctgatcgc gttcccgggc
     6241 ctggtcacct tcacgctgga caagaagctg gaggtcgatc tcgacaccat cgagatcaag
     6301 atcgagggca gcggcggcgg cgatggcggc ggctggggcg caccgcagtc cgacagctgg
     6361 ggcggcggcg cggcacccgc cgagccggtc cagggcggcg atgcacccgc cgagggcggc
     6421 agcgcggcac ccgccggaga ggccgcaccg accggcggca acgagggctt tggcacgcaa
     6481 cagcgcggct ggtaggcgcg cagcgtactc ccccgctggc ggcgggcgtc cgatggacgc
     6541 ccgccgcttt ttcgtgcacc gctgcatgtt agaatcgcgc gtccgaatcg cctcgattcc
     6601 gcccaacccc atccggtaag cagacgccat gttctcttcg caagacaccc tcgccaaagt
     6661 cgaccccgag ctgtggtccg ccatccaggc cgaaaacaag cgccaggaag accacatcga
     6721 actgatcgcc tccgaaaact acgtctccca cgcggtgatg gaagcccagg gctcccagct
     6781 caccaacaag tacgccgagg gctacccggg caagcgctac tacggtggct gcgagcacgt
     6841 cgacgtggcg gagcaactgg cgatcgaccg cctcaaggcg ctgttcggcg ccgaggccgc
     6901 caacgtgcag gcgaactccg gctcgcaggc caaccaggcc gtgctgatgg ccttcgccaa
     6961 gccgggcgac accatcatgg gcatgagcct ggccgaaggc ggccacctca cccacggcat
     7021 gccgctgaac atgtcgggca agtggttcaa cgtcgtggcc tacggtctca acgagaagga
     7081 agagatcgac tacgacaaga tggaagcgat ggcgcgcgag cacaagccga agatcatcat
     7141 cgccggcgcc tccgcctacg cgctgcgcat cgacttcgag cgcttcgcga agatcgccaa
     7201 ggaagtcggc gccatcttct gggtcgacat ggcgcactac gccggcctga tcgccgcggg
     7261 cttctacccc aacccggtgc cgcacgccga cgtcgtcacc tcgaccaccc acaagaccct
     7321 gcgcggcccg cgcggcggca tcatcctgat gaaggccgag cacgagaagg cgctcaactc
     7381 ggcgatcttc cccggcctgc agggcggccc gctgatgcac gtgatcgccg ccaaggcggt
     7441 ggccttcaag gaagcggcct cgcccgagtt ccgcaactac caggagcagg tgatcgccaa
     7501 cgcccgcgtg atggcgcgcg tgctctccga ggagcgtggc ctgcgcatcg tctccgggcg
     7561 caccgagagc cacgtcttcc tggtcgacct gcgcaacaag aagatcaccg gcaaggccgc
     7621 cgaggcggtg ctgggcagcg cccacatcac cgtgaacaag aactcgatcc cgaacgaccc
     7681 cgagaagccc ttcaccacct cgggcatccg cctcggctcg ccggcgatga ccacgcgcgg
     7741 cttcaccgag atcgaggccg agaagatcgc ccacctgatc gccgacgtgc tcgacgcgcc
     7801 ggaagatgcg gcggtgatcg agcgcgtgcg cggccaggtg gccgagctgt gcgcgaagtt
     7861 cccggtctac ggcaagtaag cggcgcggcg gggcgcctgc cgccccgccc gctccaccac
     7921 catgaaatgc cccttctgcg gtgaccccaa cacccaggtc accgacacgc gcgagaacga
     7981 ggacggcgac gtcgtccggc gtcggcgtcg ctgcgtgaag tgcgacaagc gcttcaccac
     8041 ctacgagcgc atcgacctca agatgccgca catcgtcaag cgcaacggca accgcaccga
     8101 gttcgaccac gccaagctcg caggcagcat gaagctcgcg ctgcgcaagc gtccggtgac
     8161 catcgaggcc atcgacgccg cggtcgaccg catcgaggcg cgcctgctcg cgatgggcga
     8221 acaggaggtg ccgagcgaga agatcggcga gctggtgatg aaggagctca agaagctcga
     8281 caaggtcgcc tacatccgct tcgcgtcggt gtatcgcaac ttcgccgacg tcgacgaatt
     8341 cgccgaggtc atccgtgaag ttcagacgcg tcctcggcgc ggcaaggccg acaagggcgg
     8401 cgcggacccc ggaaatgacc ttttcggcgg ctgaccacgc cgccatggcg cgcgcgctgc
     8461 agctcgccgc ccgcggcctc gacaccacct cgcccaaccc gcgcgtgggc tgcgtcatcg
     8521 tgcgcgacgg tgccaccgtc ggcgagggct ggcacgcgcg tgccggcgag ccgcacgccg
     8581 agatccacgc cctgcgcgcc gccggcgcgg ccgcacgtgg cgccaccgcc tacgtcaccc
     8641 tggagccgtg ctcgcacttc ggccgcaccc cgccctgcgc cgacgcgctg atcgaggccg
     8701 gcgtggcacg cgtgatcacc gcgatggaag atcccaaccc gctcgtcgcc ggacgcgggc
     8761 ttgcccgcct gcgtgcctcc ggcatcgcca ccgcgcacgg cctgctcgcc gaagcggcgc
     8821 acgagctcaa catcggcttc gtgtcgcgca tgacgcgcgg ccggccctgg gtgcggctca
     8881 aggtcgccgg cacgctcgac ggcaagagcg cgctcgacaa cggcgtcagc cagtggatca
     8941 ccggcccggc ggcgcggcgc gacggccacc gctggcgcgc gcgggcatgc gcgatcctga
     9001 ccggcatcgg cacggtgcgc gaggacgacc cgcagctcag cgtgcgcgac gtgccgtgct
     9061 cacgccagcc gctgcgcatc ctcgtcgacg cacgcctgga ggtctccgtg caggcccgca
     9121 tcctgcaggg cgaccccatc ctgatcgcca ccgcgagcac cgacgaggcg cgtatcgacg
     9181 cgctgcgtgc ggccggccac gagctcgtct gcgtgcccaa cgccgccggc aaggtggagc
     9241 tcggcgcgct gctgcgcctg ctgggcgagc gcggcgtcaa cgaactgcac gtcgaggccg
     9301 gcttcaagct caacggctcg ctgatgcgcg aaggctgtgt ggacgaactg ctgatctacc
     9361 tggccccgat gctcgtcggc gataccgcgc aggggctctt caacctgccc gcgctcaccc
     9421 gcctcgaggg cgcgacgcgc ctggacatcc gcgatctgcg ccgcatcgga gcggacctgc
     9481 gcctgatcgc gcggccgctg ccgcaagggt aagcgccgcc gggcggtgga tcgcccggcc
     9541 cgcccccgtc aggcgatcaa cgcccggcgc acaccgcgca accgggatcg cgcccgagcg
     9601 cgacactgcg ccattccatc gacaacccgt cgagcagcag caggcggcca tcgagcgtac
     9661 gcccgcagcc gatgatcacc ttgagcgcct cggccgcctg gatggtgccg acgatgccga
     9721 cgatgggcgc gaacacgccc atcaccgcgc agcgcacctc ctcgatgtcc tcggcctccg
     9781 ggaacaggca gtggtagcag ccgctgtcgg gcttgcgcag atcgaacacc gagacctggc
     9841 cgtcgaagcg gatcgccgca ccggacacca gcggcttgcg gtgcttcacg caggcgcggt
     9901 tgatggcatg gcgagtggcg aagttgtcgg tgcagtcgag caccacgtcg gcgcgtgcca
     9961 cctcggcctc gagcgcctca ccctcgagcc gcgcctgaat cggctccagg cgcgtctgcg
    10021 ggttgagtcg atgcagcgtg gcgcgcgccg aggcgacctt ggggaggcct accatgtcgg
    10081 ccgagtgcat gatctggcgc tgcaggttgg tgagatcgac cgtgtcgtgg tcggcaagca
    10141 cgacggtgcc gaccccggcg gcggcgagat acatcgccgc gggcgagccc agaccacccg
    10201 cgccgacgat cagcgcgcgc gcgtcgagca gcgcctgctg gccctccacg tcgatttcgg
    10261 gcagcaggat gtggcggctg tagcgcagca gctggtcgtc gttcatcgcc cgtctatctg
    10321 gcccgtctat ttgtattcgc gcagttcgag cggggtatcg tcgtggtcgc cgtgggcgtg
    10381 gtggtcccag gcctggatat agacctcgtt ggactgcttg atcaggcgct cgggcgacag
    10441 caggttgtgg cgctgggtct cctcgctgaa atagacgagc gcccgcacca gcttgatgta
    10501 gagcgaattc tccagcgcga agccggcctc gcgcagcgca tcttcgagcg cctcgaggga
    10561 gtagtcgagc accgagtagc gcaccacgat gcaaagcggg tcgtccgtgc gctcgagctg
    10621 taggcccttg agcagttgca gcgctctcca ggcgcgctcc acctggcccg gcggcagcgg
    10681 cttgaagcgg atgtcgcgct gcttgtggat gtcggcaccc ggcaggggcc ggtcgtgatg
    10741 ccggcccgcc agcttgtagg cagtttccct gcgcatgatc gtcccccccg gccggactcc
    10801 cggcttactg tttcgccgcc gccggctgtg cagcctcgac cgcggcggcc ttgtccccgg
    10861 ccgcctcggc cgctgcagcc tgcacggcct gcgcgatgtc ctcgcccttg agcaggcgga
    10921 tcgcctgctt gagctgatga tcgttctcgc cggcgagctc gaagcgcacc ggctccgccg
    10981 actcgtcctc caccgccgcg ccatccccct tgcccgcagc cgtggtggcg gccttggcag
    11041 cctccccggc gcccttgtcg ttctcgaggt gacccagcag gtcggcctcg cgcacacggc
    11101 ggctggagcc gttggcggtc tcctcgacga cgatgtcggg ctcgatgccc ttggcctgga
    11161 tcgagcgccc gctcggcgtg tagtaacgcg cggtggtgag cttgatcgcg gtgttgttgt
    11221 tgaggggcag gatggtctgc acggagccct tgccgaaggt ctgcgtgccg atcaccttcg
    11281 cgcgcttgtg atcctgcagc gcgccggcga cgatctcgga ggccgaggcc gagcccgcat
    11341 tgaccagcac caccatcggc acgtcgcgcg catacgccgg caggcggcgc aggaagtcgt
    11401 cgcgcgtccc gcgcagatag tcggcctgga tggcgcggta ttcacgcttg gcgtcctcgg
    11461 tgcggccgtc ggtactgacc acgagggtct cctcgggcag gaaggccgcc gacacgccga
    11521 ccgccccgtg cagcaggccg ccggggtcgt tgcgcaggtc gagcacgagg ccctgaaccg
    11581 gcccctgggc agcgagcttg gcgagatgct cgaccaccga agccgcggtg ttctcctgga
    11641 actgggcgat gcgcaggtag gcgtagccgg gctcgaccac cttggacttg acgctctgca
    11701 ccttgatgac ttcgcgcgtc agcttgatca cgatcggctg cggctgcccc ttgcgcatga
    11761 tggtcagggt gatgtcggtg cgcggcttgc cgcgcatgcg cttgaccgcg tcgttgaggc
    11821 tcatgccctt gaccggggtg tcatcgagct tgacgatcag gtcgcccgcc agcacgccgg
    11881 cgcggaaggc cggggtgtcc tcgatcggcg agatcacctt gacgaagccg tcctccatgc
    11941 cgacctcgat gccgaggccg ccgaactcgc cctgggtgcc gacctggagg tccttgaagg
    12001 cctcggcgtc gagataggcg gagtgcgggt ccagcccgga gagcatgccg ctgatcgagt
    12061 cggtgatcag cttcttgtct tccacaggct cgacatagcc ctgcttgatc gcattgaaca
    12121 cgtcggcata ggcgcgcaac tcgtccaccg ggagcggcgg gggcacgctg cggtcggcgt
    12181 tggcggagaa attgaggctg atcatgatcc cggccaccat gccggtcatg acgaggccga
    12241 actgtttcag cttgctgctg cgcatgagaa ctccagtagt gcgccgaccg cccgggccgg
    12301 ccatcccgtc tagttgagcc gcatccactg catcggatcg atcggcagcc cccggtgacg
    12361 gatctcgaag tataaacccg aatcgttgcc tactccggcg ctgcccacgc tggcgatcgg
    12421 ctcgcctcca ccgacccgct cgccctcctc cttgagcagg gcatcgttgt tgccatagat
    12481 ggtcaggtag tcgccgccgt ggtcgacgat gatgaggttg ccgtagccgc gcaaccagtc
    12541 cgaaaagacc acttccccgc ccgccaccgc acgcacctcg gcgccgtcgc ccgcacggat
    12601 gaacacgccc ttccaggtgg tgccgccctc tgcccttgga gcgccgaagc ggccgacgag
    12661 ttctccgcgc accggaaaac gcagctgccc gcgcaactga ttgaagcgca cgccggtggg
    12721 ggtcgcaccg gcggcgtcgc ggacctcgcc gacgacaggc tcgggccgct gcgcccgctc
    12781 cacccgcgcc ggcggcggct cctcgacgcg cggagccggc tccggtgccg cgcgcgcagc
    12841 ggtctcgccg cgcggttcct gctccgcgcg cgcgcgcgca gccagggccg ccaggcgctc
    12901 ggcctcgcgc tgcgccgctt gccgacgctc ggcctcgcgc tgcgcggcgg cgcggcgttc
    12961 ggcctcgcgc tgctccgctt cacgacgcgc ggcctcgcgg gcggcggcca ggcgcgcacg
    13021 gcgggcgagg gtctcgatga gcttgccgag gcgctgctcg tcctgctgca gcgcgtcgac
    13081 ctcggtcttc ttcgccttca gctcgcggct cacctccgcg agcgcggcct tgcgccgcga
    13141 ctgctcggtc tgcagctgct gctggcggcc gcgctgctcc cgctcgagcg cggcgaggcg
    13201 gtcgcggcgc tggacgatct cgtcggcgcg acgccgggtc tcggcgaggt cggtacgcag
    13261 accttcgatg agctcgaggc gggcacggcc gaggtgctcg aggtagtgcg cgtcacgcgc
    13321 gagctggttc gggtcgcgcg ccgacagcag cggcgccacg ccatcggccg ccccatgtac
    13381 gtaatggcgc cgcacccagt cggccagctc gccgcgacgc gcgtcgatgc gcgcggcagt
    13441 ctcgcgctgc tcgccctcga gcaccgcgag ctgcttctcg gcccccctgc gctcgccctc
    13501 gatgcggccg agctcgcgca ccgcgcgcga caccgcgcgc tcggactcga cgagggcctt
    13561 ctgcgcagtg ctgcgctcgg cctcggccct tgccatctcg tcctgcagtt cgcggatgcg
    13621 ctgcttgagc tcgtcgaggt cggagcgccg ctcggcgatc tcgccgccgg cctgggcaag
    13681 cgccggacga ggcacgccgg ccaaggcgac gaacgcggcg acgcaggcgc cggcgagcag
    13741 cgggttcagg cttctgggtg acaacggggg tggaatccgc ggaatcttgc gagtgggaac
    13801 gaaggcgtgg cgagcaggaa cgatggcgat gcgacgatac cccgcggccg cgcgaaccgc
    13861 actccgcgac ccggtgcagc cgcaggcgcg atctctcatg catcggaaca acgcgttatt
    13921 ttatactagc gctttgattc tgccggcccc atcgtggaca aagacgcaat cagcaccctg
    13981 atcgacaagc acgaacacat cgagaccgcc gcgcgcgcgc tcaaggcgat cgcgcatccc
    14041 ctgcgcctca agatcctctg cgtgctcggc ggcggggaag aatgcgtgca ggacatcgtc
    14101 gatgccgtgg gcacctcgca gagcaacatc tcccagcatc tcgccatcct gcgcgacaag
    14161 ggcgtgctgc agacgcgcaa ggacgccaac cgcgtctatt accgcgtcgg cgacgagcgc
    14221 accctccagc tgatcgtgct gatgcgcgag gtcttctgcg cccccgacgc ggacgaacgc
    14281 tgatccccaa cccccgcaac cggagcatcc ccctagtgga attcctgcaa cagaactggt
    14341 actgggccgc gctcgccgcc gcctcgggca cctggctcat ggtcgagctc atccgcagcc
    14401 gcggcgacga cacccagctc tcgccggtcg aggcgaccct gctcgtcaac cgcgaggacg
    14461 cgatcgtcat cgacgtgcgc gaacagggcg aatacgccca gggccacatc cccaatgcgc
    14521 gccacatccc cgccggcgag atcgagcgcc gcagcaagga aatggaaaag tggaaggacc
    14581 acccggtcat cctgtgctgc gccaccggcg cgcgctcgaa cagtgccgca ggcgccctgc
    14641 gcaaggtcgg gttcaaccgc atctacaatc tgcgcggcgg catgatggaa tggcagaagg
    14701 cgggacagcc cgtcagccgc aagaggaaat gagcatgcag cccccgatcc gcatgtacgc
    14761 gaccgcaacc tgcccctact gcatccgcgc cgagcagttg ctgctcgaca agggcgtgac
    14821 cgggctggac aagatccgcg tcgacctcga ccccgcgcgc cgcgaggaga tgatgaagct
    14881 gagcgggcgc cgcacggttc cgcagatctt catcggcgac taccatgtcg gcggctgcga
    14941 cgatctcttc gccctcgagc gcgccggcaa gctcgacccg ctgctgcgcg gcgaggccgc
    15001 ctgagcgcga gtcgcggcaa agcaggccgg gaaacccacc gccctaccct ttccttccgc
    15061 ggtcgcagtc gcgaccgcac ccaacccaac cggaacccga ttcatgagcg aaaacgccca
    15121 acccgtcttc tcgatcgaaa aactctacgt caaggatctc tcggtcgaag tgccgggcgc
    15181 cccgcagatc ttcctcgagc gcgagacccc gcaggtgaat gtgcagctgc gcaccgaagg
    15241 ccaggtggtc gaagaaggcg tgtatgaagt caccctcacc gtcaccgtca acgcccgcat
    15301 cggcgaggac cgcaacctgt tcctggtcga agtggcccag gccggcatct tccagatccg
    15361 caacctgccc gaaggcgagc tcgagccggt gatgatgatc ggctgcccga acatcctctt
    15421 cccttacgcc cgcgaggccg tgtccgacgc ggtcacccgc gccggcttcc agccggtgct
    15481 gctgtcgccg gtcaacttcg agtcgctcta ccagtcgcaa cgccagcagg ccatcgagca
    15541 ggccatgcag aaggcgaacg gcgaagtgcc gatccagtga ggcttcccgc atgaagcgcg
    15601 cgcgccgtcc gtccccgcag agcctgccgg cgccgctcgg gcgcgcgctc ctgaacctcg
    15661 ccgcgctcgt cgccctgggt ggcgcggcgc tgccggtcgc cgcgcaggcg atcgagtatc
    15721 gctccgccgg agcgggggcc ctgctgcgcg aacgccccgc ggcggaagcc gagccgcagt
    15781 tccgcctgcg tcccggcacg ccggtcgagg tggtcgtgcg cgaggacggc tgggtgcgcg
    15841 tgcgcgaccc tcaaggcggg ctcgcctggg tcgagggcag cgcgctcacc acacgccgga
    15901 cggtcatcgt caccgcggag cgcgccgtta tccgccgcgc gccgcaggag tcggccgcac
    15961 ccgccttcga agccacgcga cacgtcgtcc tcgaactgct cgagcccgcc agcgagggct
    16021 gggcgcgcgt gcgccacgtc gaaggcttcg agggtttcgt gcgcgccggc gaggtatggg
    16081 gactgtgagc cgctgccgca tcgccgtgtt cggcgcgggc gcctggggca ccgcacttgc
    16141 ccaggccttc tctgccagcc acgacgtcgt gctgtgggga cgcgaccgcg accagctcga
    16201 cgagatcggc cgcctccacg agaacagccg ctacctgcgc ggcgtgcgcc tgcgcgacgc
    16261 gctcgcggtc gagcccgact tcgcgcgcgc cgccgtcgat gccgatctgc acctggtcgt
    16321 caccccgctc gccggcctgc gcaccacgtt gcgcgagctg cgccggctcg cccccgggcg
    16381 cgccctgctg tgggcatgca agggcttcga ggccggcacc ggcaagctgc cgcacgagat
    16441 cgtcgccgag gagtgcggcg ccggggccgc cagcggcgtg ctcaccggcc cgagcttcgc
    16501 cgccgaggtc gcgcgcggcc tgcccgccgc gatcgcgctc gccgcgcacg acgccgactt
    16561 cgcccgccac tgggtgggcg tgctgcacca gccgcgcctg cgcatctacg ccaacaccga
    16621 cctcgtcggc tgcgaggtcg gcggcgcggt caagaacgtc atggcgatcg ccgccggggt
    16681 ctccgacggc atgggcttcg ggctcaatgc acgcgccgcg ctgatcaccc gcggcctcgc
    16741 cgagatcgcc cgcctcgcgc gcgcgctcgg cgcacgcggc gagaccctga tgggcctcgc
    16801 aggcatgggc gacctcatcc tcacgtgcac cggcgacctc tcgcgcaacc gccgcgtcgg
    16861 cctcgcgctg gccgaaggca agggcctcgc cgacatcctg cgcgaactcg gccacgtcgc
    16921 cgaaggggta tcgaccgcac gcgaggtggt cgggctcgcg cgccggcacg gcgtcgagat
    16981 gccgatctgc gaggccatcg acgccctgct ccaccacggc ctggacgcgc gcggcgcggt
    17041 cgagcgcctg ctcgcgcgcg atccgcgcgc ggagtgagcc gccgcgcccg ctgccgcccc
    17101 gtgcgcttgc ggctcagtcg ccctggtccg ccgcgccagc gaagccgtgc tgacgccagc
    17161 cctcgtacac caccaccgcc accgcgttcg acagattgac gctgcgattg gtcgggcgca
    17221 tcgggatgcg cacccgccgc tcgggcgcga agtcgcgcag gacctcctcg ggcaggccgc
    17281 ggctctccgg accgaacagc aaggcatcgc cgggctggaa atccacccgg tcgtggcgtc
    17341 ggctcgcgcg cgtgctcatc gcgaacatgc gccgcccggc gagcgccgcc tggcagtgcg
    17401 cccagtccgg atgcaccgtg aggcaggtca ggtcgtggta gtcgagaccg gcgcgggcga
    17461 gctgcttgtc cgacaggtcg aagcccagcg gcgccaccag atggagacgg cagccggtgt
    17521 tggcggcaag gcggatcacg ttgccggtgt tgggcgggat ctcgggctgg tagaggacga
    17581 tctcgaacat cgctggagag gcaggctggc cccggaacgt gccggggcgg gaattgggag
    17641 acggtgggag tcgctggtcc gcgaaccgca acgggcacct tgaatccggc aaggcgggtc
    17701 ccctgcaccg cagccgcggg ccgccgagtc tagcaggccg gcaccggcgc aggcgcggaa
    17761 ttccgccgcc accttcgcgc ctgccggcgc tcctacacga accaccgcgc gccccgcctc
    17821 ctgtaggagc tgcggcagct gcgaaccagg nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17941 nnnnnnnnnn gcagctgcga accaggcggt cgggcaggcg acgccggcgc ggactgtacg
    18001 gccgcattcg cgcctgccgg cgctcctaca cgaaccaccg cgcgccccgc ctcctgtagg
    18061 agctgcggca gctgcgaacg gggcggtcgg gccggtgacg cgggctcaat agggagaagg
    18121 cgtgcgcgcc acaaccaggt tgccgaccca gctcgcccct ttccctttca ggcagcgcgc
    18181 cagctcgtcg agggtggcgc cggtggtcat cacgtcatcg accacgatga cccggcgccc
    18241 gttcagatct tccacgcact cgaaggcgcc gcgcgggctg cgcaggcggg cctcgcggtc
    18301 gagcccggcc tgcgccggca ggtcgcgcag cttgcgcacc acggcgagcc cgagcggcag
    18361 ctcgcgcgca cgcgccaggg cgcgcgccag ctccaccgcc tggttgaagc cgcgctcggc
    18421 gagccggcgc gggtgcagcg gcatcggcag cacgaggtcg accgcgccgg aatccgcacc
    18481 gaaatccgcg ccgcagcgtg ccagcgcatc gcccagaaag cggcccaccg cgagctggtg
    18541 gcggtacttg agcgcgtgga tcatcgcgtc gaccgggaag gcgaaatcga acaccgcgcg
    18601 cgtggcgtcg aaggccggcg cgccgcgcct gcaggcggca cagcggccgc catccaggcc
    18661 gggcaggccg cattgcgggc aggcagtggg cggacgccgc ggcagctcgt cggcgcaggc
    18721 gctgcagaca gcctcgccgc cgctcgtcgc accgcagacg aagcagtcct gcggtgcgag
    18781 cacgtccatc gcatggttga gcaggacgcg caggggatgc agtgaatttg acaagatttc
    18841 caccgatgga agaacattcg ggcctcgtaa ttcgtaatta cagcccggaa agcattacat
    18901 gacaacgact tccgcaacga tcgagcgccc cgcagcgccc cagtcccgcc acagatgggc
    18961 ggtcgccgag gtcgaggcgc tgttcgagct gcccctgctc gatctggtct tccgcgccca
    19021 gcaggtgcat cgcggccact tcgatccgca ggaagtgcaa cgctccaccc tgctctcgat
    19081 caagaccggc ggctgctcgg aagactgcgg ctactgctcg cagtccgccc gccacgacag
    19141 cggcctcgcc cgccaacgcc tgctcccgat cgacgaggtg ctcgccaacg cgcgcgcggc
    19201 caaggcccga ggcgcgagcc gcttctgcat gggcgccgcc tggcgtggcc cgaaggacca
    19261 ggatctcgcc ccggtgctcg agatggtgcg cgaggtgaag gcgctcggcc tgcagacctg
    19321 cgtgaccctg ggcatgctca aggagggcca ggccgagcag ctcgccgacg ccggtctcga
    19381 ctactacaac cacaacctcg acacggcgcc ggacttctac ggccaggtga tcaccaccca
    19441 caccctgcag gaccgcctcg acaccctgga caaggtgcgc ggcgccggca tcaacgtatg
    19501 cagcggcggc atcgtgggca tgggcgagaa ccgccgccag cgcgccgcgc tgatcgccca
    19561 gctcgccaac ctgcccaccc cgcccgagtc ggtgccgatc aacaacctcg tccaggtccc
    19621 gggcacgccg ctcgccggtg cgggtgcgct cgaccccttc gagttcgtgc gcacgatcgc
    19681 cgccgcgcgc atcaccatgc cggcgagctt cgtgcgcctg tccgccggcc gcggcgagat
    19741 gagcgacgag ctgcaggcgc tgtgcttcat ggcgggcgcc aactcgatgt tctacggcga
    19801 gcgcctgctc accaccgaca accccgacgc cgaccgcgac gaccgcctgt tcgcgcgcct
    19861 cggcctgcgc gcgatctgag cgccgcacgc atggacgcga cccgccaggg cctcactgcc
    19921 aacgagcccc ccgccgcgcc gggcttcacc ctcgaccgcg gcctgctgcg ccgccgcttc
    19981 gagcgtgccg cgccgcacta cgacgccgcc gacgcgctgg cgcgcgaggt cgcgcggcgc
    20041 atggatgagc gcctcgacta catccgcctg agcccgcagc gcgtgctcga cctcggctgc
    20101 ggcaccggcg ccgacctgcc gcgcctggcc gagcgctttc ccgcagccac cctgctcgcc
    20161 gccgacttcg cgcccgcgat gctcgcgcgt gcgggtgtgc gcctgcgccc gcagggcggc
    20221 ggactgctgc gtcgcctgat cggcggacgc cccgccgccg caccgcactt cgtcgccgac
    20281 gcgcgcgcac tgccgctggc gcgcgccagc ctcgggctgg tgtggtccaa cctgatgctg
    20341 ccggccctcg acgatcccct gcccgccttc cgcgaggtgc atcgcacgct gcaggtggac
    20401 gggctgttca tgttctccac gctcggcccc gacaccctgc gcgagctacg cgccgttctg
    20461 cccgctgcgg cgggcgagcg ggtgcatcgc ttcatcgaca tgcacgacct cggcgatgcg
    20521 ctggtgcagg ccggcttcag cgacccggtc atggacatgg agatgctgac cctgacctac
    20581 gccgacctcg acggcctctt cgccgacctg cgtgcgtgcg gtggcaacaa cgccgccagc
    20641 actcgcccgc gcgggctctc cggtcgcagc ggctgggagg ccgcgcgcgc cacctacgag
    20701 cgcctgcgcc gcgacggccg cctgccggcg agcttcgaga tcatccaggg ccacgcctgg
    20761 aaggccgcgc cgaagaccac cgaggacggc cgcgcgatcg tgcgcttcca gccgcgcccg
    20821 cccgcccgct gagcccccac cctgccccga gcgaagaaga tgcccacccg tcccgtctgg
    20881 ctgttcgacc tcgacaacac cctgcacaac gccagcccgc acatcttccc gcacatcaac
    20941 cgcagcatga cgcgctacct cgagcagcac ctcgggctcg gcctcgacga ggccaacgcg
    21001 ttgcgcatgc agtactggca ccgctacggc gccacgatgc tcggcctgat gcgccaccac
    21061 ggcaccgacc ccgaccactt cctggtcgag acccaccgct tcgaccgcct gcacgaaatg
    21121 atggtgttcg agcgcgcgct gcgcggcatg ctgcgcgccc tgccgggccg gcgcatcgtg
    21181 ttctccaacg caccacgtca ctacgccgag gcggtgctgg agatcatggg cgtgcgccgg
    21241 ctgttcgagg acgtggtcgg catcgaggac ctcgactacc accccaagcc cggcatccgc
    21301 gcctaccgca gcctgctcca gcgccgacgc ctgaacgccg cgcaatgcat catgctggaa
    21361 gattcggccg tgaacctgcg caccgcgaag cgcctcggca tgcgcaccgt gctggtgggc
    21421 ggcgggctgc gcacgccggc ctacgtggac ctgcgcatcc ccaacatcct ggcgctgcgc
    21481 cgccagctcg ggcgcctgca ggtgcgctga ggggggaaga cacgggcgaa cggcggcgcg
    21541 gcgatggcgc cccaccgccc gcaacctcag tcgcgcactg cccgctccat caggcaggcg
    21601 ccctcgccat agccaggcgg cagcgccccc ggcaccacgg cgaagccctg gcgcacccag
    21661 aacggcagcg cgtcggcgag cgccaccagc cgcatcccac gatgccccgc gccatccgac
    21721 cagtcgcgca cgcggccgaa cagcgccgcc gcaacgccca gcccgcgcgc cgccggcgag
    21781 accgcgaggt cgtgcacgaa gccatgcgcg gcgcgcgcgg gcagcgcctg cagcggcgca
    21841 tgcaggggcg gcgcgccggc gtcgccccag ggatgggcga acacgtagcc caccacccca
    21901 ccatccgact gcgcgagcca gcacgcctgc ggcgccagcg cgagcttgcg cccgagcacc
    21961 gcggccgact cctgatagcc gtcgccgtag gccgcacgct ggatcgccag cacggcgggc
    22021 aggtcgtccg cacgcagcgg ccgcaggacc ggccgcgcgg ccgccgcgtg cgccatcgtc
    22081 acgcgccggc tttcagccag cgcgccgcgt cgagcgcgaa ataggtgagg atgccgtcgg
    22141 cgccggcgcg cttgaaggac agcagcgcct ccagcgcgca cgccttctcg tccagccagc
    22201 cgttggccgc agcggccttg agcatggcgt actcgccgct cacctgatag gcgtaggtcg
    22261 gcacctgcag ctcctgcttc accctgcgca cgatgtccag gtagggcatg ccgggcttga
    22321 ccatgaacat gtcggcgccc tcggcgatgt cgagctcgac ctcgcggatg gcctcgtcgc
    22381 tgttgcccgg gtccatctgg taggtgtgct tgttgccctt gccgaggttg ccggccgagc
    22441 ccaccgcgtc gcggaaggga ccgtagaagc tcgaggcgta tttcgccgag taggccagga
    22501 tgcgggtgtg gatgtggccg gcgccgtcca gctccgcacg gatgcggccg atgcggccgt
    22561 ccatcatgtc ggagggtgcg accacgtcgg cacccgcctg ggcatggcac agggcctgct
    22621 tggcgagcgc ctccagggtc tcgtcgttca tcacgtagcc gcgcggatcg gcggggtcga
    22681 tgaggccgtc ctggccgtgg ctggtgtagg ggtcgagcgc cacgtcggtg atcacgccca
    22741 gctcggggaa gttcgccttg agcgcctgca cggtgcgcgg caccaggccc tcggggttcc
    22801 aggcctcctc cgcgccgggg gtcttgccgg cgaggtcgat caccgggaac agcgccagcg
    22861 ccggcacgcc caggcgcacc gcctcctcgg ccacgcgcag caggcggtcg atgctcacgc
    22921 gctccacgcc gggcatcgag ggcacggcct cgctgcggtc ggcgccgtcg agcacgaaca
    22981 ccgggtagat gaggtcgttg gcggtgagca cgtgctcgcg catcaggcgg cgggaaaatt
    23041 cgtcgcggcg catgcggcgc atgcgggtcg agggaaaggc tccagtgggt cgcatctcgg
    23101 tctcttgcag gtcgtgttgg aacgtggggc ggggacgcac accgggaacg tgcggcggcg
    23161 agtgccagcc gccacgcgcg tgcagtcccc tcgcgcacgc cggcgcgcgg cggagggacc
    23221 tggcgcgcgg cttgcggaac tttcaggtga gggagtcatc ttagcaggca gatggcgccg
    23281 tgcccccagg ccggccatct cccgcttcac ctccctgagc gggtgcctca cgcctggtga
    23341 ggcatttttg cccccgacta cgtcccctgg tcgggggctt ttgtttttgc ggccggcaaa
    23401 gcatcgcccg cggcggcagg cgtgccggcc gcgtcctcgg aagccgcgcc gggcggcacc
    23461 agccagccgc cgatcacgcg ctcgacctcc tccaccccgc tcttcttgag actggagaac
    23521 agctgcacgc tgacctgcgg cccgagcggc tcgagcgcgc gccgcacctc ctgcagggtc
    23581 gccgcggcag ccccgcgcga gagcttgtcg ctcttggtga gcagcacgtg catgggccgg
    23641 cccgagggcg cgaaccaatc gatcatgttg cggtcgagag gcgtgagcgg atgacggctg
    23701 tccatgatca gcacgagtcc gatcaggctc tcgcgcgtgc gcaggtaggt ctcgatcagc
    23761 cccgaccact ggcggcggat cttttcgggc actgcggcgt agccgtagcc gggcagatcg
    23821 acgagcaagg cgccgttgtt gaggcggaag aagttgatca gctgggtgcg cccgggcgtc
    23881 ttcgacacgt aggccaggcg cacatggcct gcgagggtat tgatcgcgct cgacttgccg
    23941 gcgttggagc gccctgcgaa ggcgatctcc gcccccgagg gtggcggcag ccccgaaggc
    24001 ttggcgatcg agatttcgaa tgttgcgttg cggaacagag gcatggataa agatcaccgg
    24061 aaaccgcgcc ttgcgcggca aacagacctc atcgcatcgc gcaatcaggc gttcgtgtat
    24121 tagaatacct cgtttgaaac aatcactcac ggctttccga ggacatcatg atcaagcgtt
    24181 ccctgctgct ctcgtcgctt ctgctggtcg ccggcggcct tcaggcccag gaccaggccc
    24241 cggacctcga aaaggccaag cagaccgccg agacggtctg cgcggcctgt cacagcgccg
    24301 atggcaacag ccagctcccg gccaacccga agatcgccgg ccagcacgag gactacctct
    24361 tcaagcagct gcgcgagttc aagggctgga acggcaaccc cccggtgcgt gaaaacgcga
    24421 tcatgggcgc gatggtcgcc ggcctcgagg aggccgacat gcgcggcctc gcgaagtact
    24481 tcgcctccaa cgagctgaag cccgagccgg ccaagagcct gggcaccatc gagctcggcc
    24541 agaagatctg gcgcgctggc atcgccgaga agggcgtgcc cgcctgtgca gcctgccacg
    24601 gccccgcggg cgccggcatg cccgcgcagt atccgcgcct gtccggccag ttcgccgaat
    24661 acaccgaggc gcagatgaag gccttccgcg acggcgtgcg cctgaacgat ccgaacagca
    24721 tgatgcgcat gatcgcgatc aagatgacgg acccggaaat caaggccgtc gccgactacg
    24781 cgaccggcct gcgctgaccc gctgtctgcc cggccttcgg gccggcggga cgcctcgcca
    24841 cgtcaggatg tgcgcgcccg cgaaggcggg cgcgagcatg tttccgcttt ccggcgcgac
    24901 tcgcgcccgc cgcccgcaag gcgcggctcg atcgcccgcc gcaccgcctg gcctgcggtg
    24961 ccggcgtccg ttttttctcc gaggtccgga tgcatagcgg catcgcgcgc gccctcttcg
    25021 agctgctcag ctcgatgcga tttgccatct ccctgctgac gatcctgtcg atcgcctcgg
    25081 tggtgggaac ggtcgttcgc cagaacgagc ctttcaacgc ctatctcaac cagttcggtc
    25141 cgttctggtt ccccgtgttc gagaagctcg gcctgtactc ggtgtacaac gccggctggt
    25201 tcctcgtcat cctcgccttc ctggtgctgt cgaccacgct ctgcatcgtg cgccagaccg
    25261 caccgatgct gcgcgagatg cgcagcttcc gcgagcgcgc gcgcgaggcc tcgctgcgca
    25321 gcttcgccca ccgcgccatc ctcgtgccgg cagtgcccga ggccgacacg atcgagcgcg
    25381 cgcgggccta cctcgcgcac gcgggcttcg ccagccgggt ggccgacaac ggcgaaggca
    25441 ccctgctcgc cgcccgccag ggcagcgccg ggcgcatcgg ctacttcctc gcccacggcg
    25501 cgatcgtgct gatctgcgtg ggcggcctgc tcgacggcaa cctgccactg cgcctgcagg
    25561 tctggctggg cgacaagcac acgaccactg gcaaccagct catcgccgac atccccgagt
    25621 cggcccggct cggcaccggc aacccgagct tccgcggcga cgtcttcatc cccgagggtc
    25681 gcaccaccag cttcgccgtg ctcgggctcg ccgacggcat cctgctgcag gagctgccct
    25741 tcaacgtcgc gctcgacaaa ttccacatcg agcactacga gaacggcatg cccaagcgct
    25801 tcgccagcga catcagggtc accgaccgct cgagcggcaa gaccacgcaa cacacgatcg
    25861 aggtcaaccg cccgctcacc gtcgatggca tcacgctcta ccagtcgagc ttcgaggacg
    25921 gcggctccag gctcacgatc aaggcacgca gcctgctgcc ggggcgcccc ggcgtactgc
    25981 gcgagatcga gggcgtggtg ggcgagagcc ttgcgttcgc cgacgccacc gcgggctttt
    26041 cctacacgct ggaattcacc gacttcaagg ccttcaatgt cgaggacatg cgcggcagcg
    26101 agggcgggca aggcgacgac gccccgcgcg gcatggacaa gctgcagcgc catctgggca
    26161 gcggcgccaa gggtgccgag gaccgcgaca tgcgcaacat cggccccagc ttcaccttca
    26221 agctgcgcga cccggccggc caggcacgcg agttccacaa ctacatgctg ccgatcgagc
    26281 agggcgaacg ctggttcctg tataccggcc tgcgcgacgc acaggccgac gccttccgct
    26341 acatgcgcat cccgctcgac gagcgcggca gcgtcgattc ctggttcgcg atccgcgacc
    26401 gcctgctcga ccccgcgcag cgcgacaccc tggtcggtcg cttcgccgcg cgcagcttcc
    26461 ccgcgggccg cggccaggac gcgatgcgcg aggcgctggc gcagtcggcg cggcagacgc
    26521 tcggcctgtt cgccgagaag ggctacgaga cactcggcgg cttcatcgag aagtcggtgc
    26581 ccgaggccga gcgcggccag gccgccgacg tgctggtgcg catcctgcag ggactcgcgt
    26641 tcgaggcgtg gacgctgcac cgcgagacca ccggcgaagc tgcgctcgag ttgaacccgg
    26701 cgcgcgccac cttcctcaac gacaccatcg cggcgatctc ggacagccac ttctacggcg
    26761 cccctgcctg gctgcagctc gacgccttcg aagagcgcca cgccaccgtg ctgcaggcga
    26821 cgcgctcgcc gggcatgccg ctcgtctacc tgggcgcgct gctgctggtg ctgggcgttt
    26881 tcgccatgct ctacatccgc gagcgccgcc tcttcgtgct ggtgaagccg aacgaggcgc
    26941 tggtcgcgat gtcttccaac cgcaggacgc tcgacgtcga cgagaccttc cgccagcacg
    27001 tcgaaggcct cgccgccgtg ctcggcgccc ccgtgcccgc atccgactcc agagaaggtg
    27061 cctgatggaa atcgcccgcc cctccccccg cacgccctcg cccggcacgc cctccaggcc
    27121 gcagcctccc gtcctgcccc cggccgcgct cgcgccgcgc accccgctgc tgcgccggct
    27181 cgacgccctc gactggctgt acgcactcgc gctggcgttg ggcgccgcct tcgcgctcta
    27241 ccgctaccac acggcgatgg acgtctacga cgacctcatc ctggtgctgc acgtgcccgt
    27301 gctggcggtg atcggctggc actggaagcc cttccgcgcc ttcctcgccg cggtggcgct
    27361 gctggcgctg gcgagcatcg cgctttacca gggcgatctc gcgcgcgccg aacagacctt
    27421 cctgctcaag tacctgatct ccagccagac cgcgatcatg tggatgagcg cgctgatctt
    27481 catcgccacc ggcgcctact ggctgggcct catcgggcgc agcgacttcg gcgagcgcac
    27541 cggctcggcg ctgacctgga tcgccgcgac catgggcacc accggcctct tcgtgcgctg
    27601 gtacgagtcc tacctgctcg gcccggagat cggccacatc ccgatcagca acctgtacga
    27661 ggtcttcgtg ctgttcacgc tgatgacggc gctgctctac ctctactacg agggccgcta
    27721 cgccacccgg cgcatgggcg ccttcgtgat gatcgtgatc tcgaccgcgg tcgccttcct
    27781 gctctggtac accttcaccc gcgaggcgca cgagatccag ccgctgatcc cggccctgca
    27841 gtcctactgg atgaaggtgc acgtccccac caacttcatc ggctacggcg ccttcgcggt
    27901 ctcggccatg gtcggcaccg cctacctgct cgccgcgcgc ggcatcctcg ccagccgcct
    27961 gccggccttg cgcgtgctcg aggacgtgat gtacaaggcg atcgcgatcg gcttcgcctt
    28021 cttcaccatc gccaccatcc tcggcgcgct gtgggcagcc gaggcctggg gcacctactg
    28081 gcagtgggac ccgaaggaga cctgggcgct gatcgtgtgg ctcaattacg cgacctggct
    28141 gcacatgcgc ctgaccaagg gcctgcgcgg cgcggtgctg gcgtggtggg cggtggtggg
    28201 cctgctcgtc accaccttcg ccttcgtcgg cgtgaacatg ttcctgaccg gcctgcactc
    28261 ctacggcgcg ctgtaagcgt gccgaggctc gcagcgcggt cgcccatcga ggacggaccc
    28321 gaagcatgaa tcccaacccc gcaggcggcg acgaccgcag cttcctcgcc gtcgatgccg
    28381 cacgcgcggc gatcctcggc gcgctcgccc ccatctccgg gcgcgagcgc gtggccgtgc
    28441 gcgccgcgct cggccgcgtg ctcgccgagg acgtgatcgc gccgtgcaac gtgcccgcgc
    28501 acgacaactc cgcgatggac ggctacgccg tgcgcgccgc cgacctccgc gccgagggtg
    28561 aaagcgcgct cgcggtggtc ggcaccgcct tcgccggccg ccccttctcc ggcatggtcg
    28621 gcaccggcca ggcggtgcgc atcatgaccg gcgccaccat cccgcagggc gccgacacca
    28681 tcgtcgtgca ggaaatggcc cgccgcgagc acgatcgcgt gttcatcccc gccggtcaga
    28741 agaagggcca gaacctgcgc cacgccggcg aggacctcgc cgagggcggg gtggcgatcg
    28801 ccgccggcaa gcgctgcggc cccgccgagc tcggcctcat cgcctcgctc ggcatcgccg
    28861 aggtgtgcgt gcgccgccgc ctgcgcgtgg cggtgatgtc caccggcgac gagatcgcct
    28921 cgatcgggcg cccgctcggc cccggcgagg tctacgacag caaccgctac accctgcacg
    28981 gcgtgctcac ccggctgggc tgcgagctgc tcgacctcgg cgtcgtgccc gaccgcccgg
    29041 aggcgctcga ggaggccttc cgcgaggcct ctcaggccgc cgacgtgatc atcaccagcg
    29101 gcggcgtgtc ggttggcgag gccgacttca tccgcgagat gatgaaccgc atgggcgagg
    29161 tggcgttctg gaagctcgcg atcaagcccg ggcggccgat ggccttcggc cgcatcggcg
    29221 acgccgtgct gttcgggctt ccgggcaacc cggtggcggt gatggtcacc ttctaccagt
    29281 tcgtgcagga tgccctgctc cagctcatgg gggtcgcgcc gctgcctgcg cccgagcgct
    29341 tcccggtgcg cgccgccttc tcgatgcgca agcagcccgg ccgcgtcgaa tacctgcgcg
    29401 gccgactgca gcgcgacggc gggacacttg ccgtggcgct cgccggcgcg cagggctccg
    29461 gcgtgctgag ctcgatgtcc gaggccgact gcttcgtcgt cctgccggcc gactgcaccg
    29521 cagtgcagga gggcgacacc gtgctcgtgc aacccttcca cggcatcgtc tgagcaccct
    29581 gccgcacctt cctcctcacc tcattccctt ccccgcgcac atgacccagg acgaactcaa
    29641 gaaagctgcc gcccacgccg ccctcgacca tgtggtcgaa gacagcatcg tcggcgtcgg
    29701 caccggctcc accgtcaacc acttcatcga cgcgctcgcg ggcatgcgcg atcgcatccg
    29761 cggcgcggtc tccagctccg aggcgagcac gcagcgcctg cgcgcgcacg gcatcgaggt
    29821 cttcgacctc aacggcatcg agtcgctgcc ggtgtatgtg gacggcgccg acgagatcga
    29881 cggcggcttc gcgatgatca agggcggcgg cggcgcgctc actcgcgaga agatcgtcgc
    29941 cgcggtctcc gcgcgcttcg tctgcatctg cgacgcgagc aagaaggttg acgtgctcgg
    30001 ccgcttcccg ctgccggtcg aggtgatccc gatggcgcgc agccacgtcg cccgcgagct
    30061 gcgcgccatc ggcggcgagc cccggctgcg ggagggcttc gtcaccgaca acggcaacct
    30121 gatcctcgac gtgcatgggc tgtcgatcag cgatccggtg gccaccgaga cgcgcatcaa
    30181 ccagatcgtc ggcgtggtca ccaacggtct tttcgccgtg cgcggcgccg acgtgctgct
    30241 gctcgccgcc cccggcggcg tgcaaaggct ggacgcgcgc tgagcgccct gcatggcagg
    30301 cgtgttgcag gcaacaaaac cttaacaatc gcctgttagc ctgcacgctt cccggactgg
    30361 atcgtggcga acatgaccga acacactctc aggcagtacg acatcgaact cgaagaagtc
    30421 cgccgtggcg tcctcaacat gggcggcctg gcggaaaccc aggtggtcaa ggcgatcgag
    30481 ggcctgcgca gcggccagct cgacctgctc gacaccgtga tcgaaggcga caagccgatc
    30541 aacctggcgc agatcgagct cgacgacgac tgcagccaca tcatcgccaa gcgccagccg
    30601 gccgcgggcg atctgcgcct cgtgctctcg gtgatcaaga tcgcctccga cctcgagcgc
    30661 atcggcgacg aggccaagaa gatcgccaag gccgcgcgtc gcctgcacag cgcggaggcc
    30721 cccttcgtgc cgcgcgtggg actcacccag gcggtcgagc tcgcgctcga gctcttgcgc
    30781 gcttcgctcg acgccttcgc ccgggtcaat ccggaaggca tcgaagacct gcgccgcaag
    30841 gacgcggaga tcgacgccgg cttcaagggc gtgatgcgcc agctcatcac ctacatgatg
    30901 gaagacccgc gcacgatctc cagctgcctc gagatgctgt tcattgccaa ggcgatcgag
    30961 cgcgtcggcg accacgcgat gaacatcgcc gagcacgtgg tgttcgtggc gcgcggcgag
    31021 gacgtgcgct tcgagaacac gcaggcgaag ctcggcaagg ggtgaggctt cagccgtcag
    31081 gcatgaaaaa ggggaccctc gggtcccctt tttcatgctg cacattaccg gctcagggtt
    31141 gcggcgggac gtagccggcg atctggtcgg cgccgccctc gaagaagtgc ttctccatct
    31201 gctcggccag atacttgcgc gcgcgcgcat ccatcaggtt caggcggttc tcgttgatca
    31261 gcatggtctg gtacttgacc cactgctgcc aggcttcctt cgagacgttc tcgaagatgc
    31321 gcttgccgag cgcgccgggc accggtggca ggtccaggcc ttcggcctcg cgaccgagtt
    31381 tcacgcagtt caccatgcga gccatgttca atcctctctg cttgcgggtt catcggggtt
    31441 cgaggacggc attctagccg attcaccgcc ccgcctcccg gacaccgcag cgcgattgcg
    31501 tccctcggac ttggcgcgat agagcgcctc gtcggcggcg gccaccagcg cctcgccctc
    31561 gcgcgcgttg tcggggaagc gcgcgatgcc cacgctcgcg gtcaccgcgg cctcgcggcc
    31621 gtcgaagacg aagcgcatcg cggccaccgt ctccaccagg cggtgggcga gttcgcgcag
    31681 gccctccgcg ctgccctcgg gcaccagcag ggcgaactcg tcgccgccga cccggaagag
    31741 cgtctcgttg cggcgcacgg tgcggccgag ctcgaccgcc aggcgcacca gcacctcgtc
    31801 gccggcctgg tggccgaagg agtcgttgat cggcttgaag ccgtcgaggt cgaaggcgag
    31861 caggccgagg cgactgccac ggcgctcggc gtcggccagc atgcgaccga gctcctcgtg
    31921 gaaacggcgg cggttgtaga ggccggtgag ctcgtcgcgc tcggccagct ccaccagccg
    31981 catcgaggtc cggcgcgcca ccgtgacatc ctcgtagatc cacaagcgac cgatgcgccg
    32041 cccggcctcc tcggccgcga ccaccgccga gcggtccgtg gcgatgcgac catcggtgaa
    32101 gtggaactcg tattcatcgc tgatcgcctg cttgccacgc acggtgcggt cgatgtgcgc
    32161 gaggtaggct gcaggatcgg aaagcaccac cggcgcccgc tccttgagca ccgcgtcgcg
    32221 gcagccgacc agcaaggtct cgggcggata gccccagatc tccagcatcg cgcggttgtg
    32281 gtagagcacg cggcggtcct ggtcgatgaa caggatgccg atccggatca ggttgagcag
    32341 cgcagccagg cgctggcgct cgtcgttgct gcgcacgagg tagagctcgc gcagagcctc
    32401 ctggcggcgc agctcggcca ccgtctcgag caaggtgaac tcggtctcct tgcgcgcctg
    32461 gatatgctcg gcggacaggc gcacaccgcc cccggcgcgc ggacgccagt gcgtctgcac
    32521 ccagacggtg tggtcgtcgc gcgtgcgcag gcgcagctcg aaggcctgct cgatgccttc
    32581 cgcctcgacc cgctgcgcca tgcgccggca gaacacgcgg tcgtcctcga acaccagcag
    32641 ttcgaaggga tcggccgcgc cgacgcagtc ctgcgcgctg aagccggtga gcgcctcgat
    32701 cgaggggctg atccagcgca acgccaaacc cggcaggaag accgcctcga cgctgcgcac
    32761 accgagcgcg atctcggcga gcagttcggc gtcttcccga gcgccgggag ccgggcaggc
    32821 gctcatagcg gcttgacgaa caccttggaa cggcgctgga agttgtacag ctcgcgcttc
    32881 tgccgcggca gcgcctccgg gccgatctcg ctgaaaccgc gctcgcggaa ccagtgcgcg
    32941 gtgcgggtcg tgagcacgaa cagacgctcg agacgctgca cgcgcgcgcg ccgctcgatg
    33001 cgcttgagga gctggtcgcc gagaccggcg cggcggtact cgggcgtcac ggcgaggcag
    33061 gcgagctcgg cggcgttgtc ctcgctgaac ggatacagcg cagcgcagcc caccagcacg
    33121 ccgtcgtgct cgaccacggt gaagcgctcg atctcctgct cgagcagttc gcgcccgcgc
    33181 cgcaccaggg tgccgtcggc ctccatcggc gagatcagcg ccaccagggc ggcgacgtcc
    33241 tcgaccgtgg cctcgcgcag gcggaacagc gggtcgcgcg acaccacggt gcccacgccc
    33301 gcgtgcgtga agaactcgag cagcaggccg ccgtcgaggt cgtggtcgat gaggtggcag
    33361 cgcgccacac ccttgcgcac cgcgcggatc gcgcacggca ggaacaggtg aaggtcctcg
    33421 gtgaggccct cgccggtatc gagcttgctc tgcgcctcgt cggcggtgac cgactcgacc
    33481 agctggccat cctcgccgag cagcccgggg gcgtcgcaca ggtagatcag cttctcggcc
    33541 ttgagcgcca ccgccaccgc ctcggccacc tcctccatcg cgaggttgaa gatctcgccc
    33601 gccggcgaga cgccgagcgg ggtgatcagc accacgttct gctggtcgag gtcggcgttg
    33661 atctcctcgg cgatgatctt gcgcaccgcg ccggtgtatt ggtaatcgac gccatcaacc
    33721 acgccgaccg gccgcgcggt gatgaagttg cccccggtga cgcggatgta gctgcccgcc
    33781 atcggcgtgt tgggcaggcc ctgcgacagc agcgcctcga cctcgaagcg ggtcaccgcc
    33841 atcgccgact tgacgcactc cagcgcctcg ggatcggtca cccgcaggcc atggtggaag
    33901 cgcggctcca gcccgcgacg cgcctgctcg gcgtcgatct gcgggcgcgc gccatgcacc
    33961 agcaccaggc ggatgccgag cgcggcgagc aggttgcagt cgtaggcgag gctctgcgcg
    34021 cgcttgccgg cggcgacctc gccgccgaag ccgacgacga aggtacggcc gcggaaggcg
    34081 tggatgtagg gcgcggcgcc gcgcacccag gccacgaact gggccgtggc gtcatccacg
    34141 cgtggaaccg ccgcggaggg agaggaggtt tcggaactgg aactgctgtt ttcggcgctc
    34201 acgcattcac cgctgttggg gccggacacg cacggggcga cccggcggac tggaatcgat
    34261 gacggattct agcccggccg ggcgccggcg tggaacgcgg gtgcgcgcgc tttcagccct
    34321 tgtacggccc cgcgccgagt ccgatcgggg cgggcgcggc ggcgacgagc ctggagaaga
    34381 tctgcgcgaa gtcctcctcg ccggcgcggg cggtggcgcg cgtgccgctg agcgggtcgt
    34441 cggcgacgaa gccggcgttg gcgcgcgccc agtcctcggc ggtgaagtgc ttgcggatct
    34501 gcggcagcac ctcgcgctcc tcggtcatca tgtggttgcg gtagaaggcg gcgtagtcgt
    34561 tgaaggcggc cttgaaggcc gcgaagccgc cggcggggtc gtgcgcgtag ccctggaccg
    34621 ccgcctcgag caccgcgatg cgggcgtcgg cgtcggcgtg ctcggcctcg agcctgtcga
    34681 gcgcggcgtc cgcgtcgtgc gtgcgcgcgc gcagcgggcc gaagaggaag gcgtcctcct
    34741 tggggtggtg gcgcttctcg gggtaggcct cgaggtaatg caccatcgcc tcgagcagct
    34801 tgtggtccgg ctgcaggcgg ccggcctcga tctcgccgat catgtgccgg atggcgtgga
    34861 tgatcgccgc cagcgactgg tgttcgtcca tcaggatgcg catcgcgtcc atggtctggt
    34921 ccttttccgt agggggcaga ggggctcgtg gctcaggtcg acagcatcgc ctggtgcttg
    34981 ccgccgagcc cgaggtaggc ctcgatcacg cgcgggtcgt ccgccagttc gtgcgccggg
    35041 ccctgcatgg cgatctggcc ggtctcgagc acgtaggcgt agtcggccac ctgcagcgca
    35101 gcgcgcgcgt tctgctcgac gagcaggatc gacacgccgc gccggcgcag ctcgccgatg
    35161 atgcggaaga tctcgcgcac gatcagcggc gccagcccca ggctgggctc gtcgagcatc
    35221 agcagcttcg gtttggccat cagcgcgcgg cccaccgcca gcatctggcg ctcgccgccc
    35281 gacatcgtgc cggcggcctg gtcgcggcgc tccttgaggc ggggaaacag cgcatacacc
    35341 tcttcgagcg tctgcgcgtg gtcgcgcttg cccatgcggt agcgctggaa ggcgcccagc
    35401 accaggttgt cctcgacgct catctcgccg aagagctcgc gcttctcggg caccagcgtc
    35461 atgccgcgcg ccaccatgcg ctcgacctcg ggcacgcctt ccacgcggcc gtcgaaggcg
    35521 acctggccgc gcgagccgag cacgcccatg atcgccgaca gcatcgtcgt cttgcccgcg
    35581 ccgttggggc cgatcacggt gacgatctgg ccctcgccca cggtgaggct ggcgtcggtg
    35641 agcgcctcga ccttgccgta ggacacgcac aggtcgcgga cctcgagcac cgggttcttc
    35701 gcgcccgcgt tcgaggcggc ggcgctgtct tgcttttgct gtgtcatcgc gttctctccg
    35761 ctcattccac accgcccaga taggcctcga gcaccgccgg gttctgctgg atctcgtcgg
    35821 gcaggccctc ggcgatcttc tggccgaact ccatcaccac cacgcgatcg accaggctca
    35881 tcacgaagtc catgtcgtgc tccacgatca gcgtggccat gccctcggcg cgcagcttct
    35941 tcaacagctc gccgagcgcc tccttctcct tgaagcgcag gccggccgcg ggctcgtcga
    36001 gcagcagcag gcaggggtcg gcgcacagcg cgcgcgcgat ctcgaggatg cgctgctggc
    36061 ccagggcgag gctgccggcc tcctcgtaca tgtgctcggc caggcccacg cgctcgatct
    36121 ggcgggcggc ctccttgagg atgcgcgcct cttccgcgcg gtccaggcgc cacgccgagc
    36181 tcagcacgcc cttgttgctc ctcaggtgcg cgccgatcgc cacgttctcg agcacgctca
    36241 tcgtcggcag cagcttcacg tgctggaagg tgcggctcat gcccatgcgg gcgatctcgc
    36301 gcgagtcgtg gccagccacc ggcttgccga ggaacagcac ctcgcccgag gtcggcgtgt
    36361 ccaccccgga gatctggttg aacatcgtgc tcttgcccgc gccgttgggg ccgatgaggg
    36421 cgaggatctc gccggcgcgc acctccaggc tcatgttgtt gttggcgacc aggccgccga
    36481 acctgcgcgt gacctccttg gcctcgagga tcagctcgcc cgccttgggc agcgtgcgcc
    36541 gcggcagcgg ctcggcgtcg gcgtcgagcg tcctgcgcac cgtgcgcacc ggcaccagct
    36601 tcctgaggat cggccacagg ccctcgcggg cgcggtgcag caccagcacc atgagcaggc
    36661 cgaacacgat ggtctcgaag ttgcccgtgg cgccgagtag gctgggcagc cagttctgca
    36721 gccactgctt gagcacggtg atcacccccg cgcccacgat cgccccccat acgtagccgg
    36781 cgccgccgac caccgccatg aacaggtact cgatgccgat gtgcacgccg aacggggtcg
    36841 ggttcacgaa gcgctgcatg tgcgcataca gccagcccga ggcgcacgcc agcagcgccg
    36901 cgatcacgaa gatcaccatg cgcgagcgcg aggtgtccac gcccatcgcc tcggccatca
    36961 cccgcccacc cttgagcgcg cggatcgcgc gcccctcgcg cgagtcgagc aggttgtggg
    37021 tggtgagcat ggccacgagc aggaaggccc agatcaggta gtagatctcg ccgccctcgt
    37081 cgagcgtcca gccgaacagg gcgatggccg ggatgccgct gatgccggtg tgcccgccca
    37141 ggctctccat ggtgccgaag aggaagtaca ggctgatgcc ccacgcgatc gtgcccaggg
    37201 gcaggaagtg gcccgagagc ttgagcgtga gcgagccgat cagcaccgcc accgcggcgg
    37261 tcagcagcag cccgaccagc agcgtgagcc agggcgaggc ccccgcccag gcgagccagc
    37321 cgggcaggtc ggtggcggtg gtgagcgccg cggtggtgta ggcgcccagg cccacgaagg
    37381 cggcctggcc gaagctggtc agcccgccca cgccggtcag cagcaccagc ccgagcgcga
    37441 ccatcgcgta caggccgatg tagttcaaca gcgtcacgta gtacggcgac aggatcgccg
    37501 gcaccagcag cagcagggcg acaaaggccc ccaggaccag acggtcggct ctcattcttc
    37561 ttcctccacg tggtggctgg tcagcgagcg ccacagcagc acgggaatga tcagggtgaa
    37621 cacgatgacc tccttgtagg cactggccca gaacgaggcg aaggcctcga gcagccccac
    37681 ggcgagcgca cccgccgcgg ccagcggata gctcgccagc ccgccgatga tcgcggccac
    37741 gaaacccttc aggccgatga gaaagccggt gtcgtagtag atcgtggtga tcggggcgat
    37801 cagcacgccc gagagcgcgc cgatgaaggc ggcgaggaag aaggtcagct tgcccgcgag
    37861 cgtgggcgag atccccatca gctgcgcgcc cacgcggttg atcgcggtcg cgcgcagcgc
    37921 cttgccgtac agcgtgcgcc cgaagaactg gtacagcgcc acgatcagca gcaccgacac
    37981 cgccaccacc cacagcgtct gcgcggagac catcagcggg ccgagctcca ggctgaactc
    38041 gctgaacgcc ggcgtgcgct ggccctcggc accgaagaac agcagcccca ggcccaccat
    38101 cgcgatgtgc agcgccaccg acacgatcag cagcaccagc accggcgccg aggcgatcgg
    38161 ctggtacatc aggcggtaca tcatcggccc catcggcacc acgatcgcca gcgtcagcag
    38221 cacctgcagc gccagcggca gcgcgtcgac cgccagcccg cccaccaccg cggcgagcgc
    38281 cagcggatag cccaggttcc agcccgccac gcccgcggcg cgccgcccct gaccggcctt
    38341 gagcgcgagc ccgccgtcga gcaccgtgac cagcgccccc atcaccacca gcatccacac
    38401 cgtggccggc agcacgcccg actgcatcat cgccagcgtc agcgcaccat aggccacgaa
    38461 ctcgccctgc tggatgaaga tcacccgcgt gaccgcgaac accagcacca gcgccagcgc
    38521 caagagcgcg tagatcgcgc cgttggtgat gccgtcctgg gacaggatca atgcaattgc
    38581 catatccatg gaaatgcctc gtccgggcgg taccttgcgg accgccgcga ttgattcgat
    38641 gtacggggaa gccccgacag acgcgcggcg ggacgccagg cgccccgccg cggaggggga
    38701 tgcttacttg agaagcgacc aggtgccgtt gcggatctcg atcatcacgc gcgagcggtc
    38761 atcgaggccg aggtgatcct cggcgctcat ggagtagata ccggtggcgc cggcgacttc
    38821 cttgacgccc tcgagcgcat cgcgcagcgc cgcgcggaac tcggccgaac ccggcttggc
    38881 caccttgagc gcggcgggaa cggccgcctc cagcaggacg cctgcatccc aggcgtaggc
    38941 gccgaagctc gacaccgagc ccgcgccgtt ggcggcctcg tacttctcga cgtaggccag
    39001 cgcgctcgcc ttgacgggat ggctgtcggg caggctgcgc gccatctgca ccggcccgac
    39061 cggcagcagc gtgccttcgc agtccttgcc gcagatgcgc aggaagtcgt tgttggccac
    39121 accgtgggtc tggtagatcg ggcccttgta gccgcgctcg cgcagggtct tctggggtag
    39181 tgccgcgggc gtgcccgagc cggcgatgaa caccgcgtcc ggcttcaccg acatgagctt
    39241 gagcgcctgg ccggtcaccg aggtatcggc gggattgaag cgctcgctgg cggcgacctc
    39301 gatgcccttg gcttcggcca gcttcttgaa ctgctcgtac cagccctcgc cgtaggcgtt
    39361 ggcgaagccg atgaacgaga ccttcctgac gttgttggcg ctcatgtgcc cgatgatcgc
    39421 cgacgccatc tgctggtcgt tctgcggggt cttgaagacc cagcgcttct tgtcgtccat
    39481 cggcgccacg atgcgcgcgg aggcggccat cgagatcatc ggcgtcttcg tttcggcggc
    39541 gacgtcgacc atggccagcg aagccgggct ggtggtggag ccgatgatca cgtcgacacc
    39601 gtcctccacg gtcagcttgc gggcgttctt gaccgcggtg gtggtgtcgg aagcgtcgtc
    39661 gagcacgatg tagctgacct tctcaccacc gatggtcgtg ggcagcagcc cgatcgtgtt
    39721 cttctccggg atgcccagcg aggccgcggg accggtggcc gagagcacga cgccgacctt
    39781 gatgtcggcg tgggcggcag tggcggcaaa ggcgaggccg agggcggcca gcagggtgtt
    39841 gcgcagcttc atggtgtctc ctccagtgct tgtgcggatg cccgatgcgg agccgggcat
    39901 gtcggggccg cgctcgaact gcagcaattc tgcaatatag aacgcgttcc ggttattaga
    39961 attgatacaa aagagcccgt caagcgaaaa ctttgtatca attcaaggag tgcgcctatt
    40021 tcgctgcgtc cgcctgccgc ggaagcgcgc ctcagcccgc ctggctgccc ggctcgaccc
    40081 ccgggatggc ggtggcgccg agtcgcagcg acagcgcatc gcaggcatcc ctcagcgcaa
    40141 gcagcaccgg gctctgcggt cgcagatcca gcgtgccttc cacgcccacg agcgcgatgc
    40201 tcatgttgat ctcgttcttg aagttgaaca ccggacccgc cgccgcctcc acgccgcggg
    40261 cgaaatagcc gctggagatc accgccagcc cttgcgcgcg gacctcggca agttggcggc
    40321 gcgcgtcgcc gagggtcgcg atgcccgcgg gaacccggcc ggactcgatc tccgcgcgca
    40381 gcagggcgtc cgtctgcgcc tcgggcagcc acgcggcgaa gacgcgcccg gcggccgagc
    40441 tcagcaggct caggctggtg ccggtcagca cgttgacggt gatcgggcgg cgcgggcgct
    40501 cccagcgcac gatcaccggt ccccgatcac tccacaccgc gagcgcgacc gtctcgttgg
    40561 tcagatcgcg cagctcgctg atcgcattca ggccgagccg gatgcggtcg acccggtcga
    40621 gggcgaccag gccgaggttg agggcgaagg ggccaaggtc gtagcgcgag gtgagccgat
    40681 cctgctcgac gagcccgctg cggatcaggc tgaccaggta gcggtgcgcc ttcgagggcg
    40741 gcatgtcggc cgcctgggcg atgtccttga gcatcatgga gcgcttgccg gcgaccatcg
    40801 cgcgcagaat gctcatgccc acctcgaggg actgaacgcc atgcttgccg tcgatctcgt
    40861 cgctcatcga agcaccctcc taaaaattac ttattgaaga atatcttccg ttatatgtaa
    40921 cataagtcca agcggaggag aacaaggatg aagcagctga aagtctatgc gatcgacggc
    40981 atcgtgcccg tggtggatcc gaccgcctat gtgcacccgt cggcggtgct gatcggcgac
    41041 gtgatcgtcg gtccggactg ttacgtgggg ccctgcgctt gcctgcgtgg cgacttcggg
    41101 cgactgatcc tggagcgcgg ctcgaacctg caggacacct gcgtgatgca cggcttcccc
    41161 ggcaccgaca cggtggtcga ggaggacggg cacatcggtc acggcgccgt gctgcacggc
    41221 tgccgggtgg ggcgcaacgc cctcgtcggc atgaacacgg tgatcatgga caacgcggtg
    41281 atcggcgaat cctcgatcgt cgccgcggca gccttcgtca aggcgggcgt cgagattcca
    41341 ccgcgcatgc tcgtcgccgg cgtgccggcc aaggcgatcc gtccgctcac cgacgaggag
    41401 atgcgctgga agagtgccgg caccgcgacc tatcaggacc tcacccgccg cagcctggcc
    41461 acgatggagg aaaccgtgcc gctgaccgcg gtggagacgg accgcaagcg cattcacatg
    41521 cccgacgtgg tcccgctggt ggaactgcgc cggcgcgaag cttgagctcc gcggcgcgcg
    41581 acggacgaca aggacttggc cgcagcccgc acgccctctc ccccgctcgg caccaggcga
    41641 tgcgtccggc gctcagcggg cgccgcgcag cgggtcggcg tcctggaagc gtcgcagcag
    41701 agagctcgac gcctcgggtg cgtggccgtc ggcgagctgc aggtgcgcgt cgagatggcg
    41761 ctcggaagac gccagcagcc gacgatagag ttcgcggcag agcagccgcg cgcgctgccc
    41821 cggccagtcg ctcgccagca gcacgtcggg cagcccgggg tcgcgcagca gcaggcggcg
    41881 gtagtcgtgg atcaacagca tccgcagcag gaaggcgctc tcgtcgccac agtctccggc
    41941 gccgtcccga agctgggcca gcaccggctg gtagcggtcg acgaaatcgc ggtacatctg
    42001 cgccaggcgc tcgagattcc aggctgcatg caccaggtcg gcgtcgctgg ccgccgcgcc
    42061 cagggccgca tccgccgcca tcaagggctt gagctgcggc agcagctcgc ccaacccctc
    42121 cccgaccagc gcgtcgaagg ccacgatcag gtcggcactc ggatgcacga agcagtcccc
    42181 gtcgagcatg ccgaagcctt gccagaacag cgccctgcgc aggcgctcgc gatccctggc
    42241 tgcgagctcg ccgaccgcga ggatcaggcg ccagcgacga tcccagcctt gcgcgctcga
    42301 agcatagatg cgccgcgagg cctcctcgat gcgctgcaga ccggagggag tcagcttata
    42361 gtcggtgcgg cgaccgcaag gctcgctcac cagccattcg tcgcgcgcca gccgaaacac
    42421 cgaggtgcgc acgaggcgct cattgaggcc gagcggctcg agcaggcgga tcaggctgcc
    42481 cagccagatg cgtccgcccc gaggcagcac cgcgtcaccg aagacggaga tgatcagcga
    42541 accggcctga acgcggtcct gcttgcgaaa tgcgtcgagg cggtcttgga tgggagtggt
    42601 cacgggcggg attcttcgac ctgcggctgg ggcccgaagt ctatcgattc cgcggggatg
    42661 cgcatagcgc cggcgcccgt tgtcaaggcg accgcggccg ccgccgcgca gcgaccgagc
    42721 gggcgtgccg ccagcttcgt cagcccgggg agaagccggc cggaccgtcc gccagagggc
    42781 agcgcaccaa caagcaaacc gatacattcg tttgcttctt tgaatatttt ttgtatcgca
    42841 ttgagaatcc agcattgctc ctcaaagaat cttgcgctga tggaagcagt cggacgaccc
    42901 ctgcaaaaaa atcataacta actgtttatt caatgtttac gcattcctaa acacgttctg
    42961 cctatcaaaa cacaggacga caacccctca tcgattagat actttgtatt gacatataac
    43021 gaatacattt gtatcgtttg actcacaaga ccacccagcc ggagagactc atgccccacc
    43081 ccttgctcga caagcaccgc gccacgctcg acagcgccct gaacgccatc gccacgcgtg
    43141 gctactggtc tcccttcccc gagatgccga gccccaagct ctacggtgaa acggcacccg
    43201 atgagggcaa gcgcgccttc gaggcccacc tgggcaagca gttcgagctc gggcagccgg
    43261 gccagaccgg ctggcatggc ggcgagagct cgccctacgg cgtggagctg ggggtcagct
    43321 accctgtgtg cgatcccgac gtgctgatcg ccgccgcgct cgaggccatg aagggctggc
    43381 aggcggtggg cgcagacggc cgcaccggca tctgcctcga gatcctcgag cgcctgaaca
    43441 agcagagctt cgagatcgcc cacgcggtca tgatgaccac cggccagggc tggatgatgg
    43501 ccttccaggc cggcggcccg cacgcccagg accgtggcct cgaggccgtc acctacgcct
    43561 ggcgcgagca gagcttcgtc ccgtccgagg ccacctggga gaagccgcag ggcaagaacc
    43621 cgccgctggt catgaagaag aactatcaga tcgtcggccg tggcgtgggc ctggtgatcg
    43681 gctgcggcac cttcccgacc tggaacacct acccgggcct gttcgccgcg ctctccaccg
    43741 gcaacgcggt catcatcaag gcgcacagca acgccatcct gccggccgcg atcaccgtgc
    43801 gcaccatccg cgccgtgctc gccgagaacg gcatcgaccc caacctggtg tcgctgtgcg
    43861 tggccaccca gcgcagcgtc acccaggcgc tcgccaccca cccggcggtg cagtcggtcg
    43921 acttcaccgg cagcaacgtc ttcggccagt ggctgatcga caactgccgc caggcgcagg
    43981 tctatgccga actcgccggc gtgaacaaca tcgtcatcga ctccacggat gcctacaagg
    44041 cgatgctggg caacctcgcc ttcacgctgt cgctgtactc gggccagatg tgcaccacct
    44101 cgcaggcgat cttcgtgccc gccggcggca tcgacaccga ggatggccac aagagctacg
    44161 acgaggtctg cgccgacctc gcgcgcgccg tcgagcgctt cctgtccaag cccgaggtcg
    44221 cgcacgccgt gctcggcgcg atccagtccg ccgacaccgc cgagcgcatc gacatcgcca
    44281 acagcggcgc gctcggcaag gtcgtgctgg cctcgcagaa gctcgacaac cccgagttcc
    44341 cgggcgccaa ggtgcgcacg ccggtgctgc tcgcctgcga cgccgccgac gagaaggcct
    44401 acatggaaga gcgcttcggc ccgatcagct tcatcgtcaa ggtcgccgac accgccgccg
    44461 gcatcgcgct ctccgagcgc gtggtgcgga cgcacggcgc gctcaccgtc ggcctgtact
    44521 cgacgaagca ggacgtcatc gacgcgatga ccgaggccac ctggcgcggc aaggtggcgc
    44581 tgtcgatcaa cctcaccggc ggggtgttcg tgaaccagtc ggcggccttc tccgactacc
    44641 acggcaccgg cggcaacccc tcggccaacg cctcgtactc ggactcggcc ttcgtcgcca
    44701 accgcttccg cgtcgtccag cgccgtcacc acgtctgagg agccgcccgt ggaatacgcc
    44761 aacatccagt tcgccgtgga ggcgggcatc gcccgcctta ccctgaaccg ccccgacaag
    44821 ctcaacagct tcaccggcga gatgcacgcc gagctgcgtg acgcgctcga ccgcgtgcag
    44881 gccgacaagg ccgcgcgcgt gctcgtgctc accggcgccg ggcgcgcctt ctgcgccggc
    44941 caggacctcg ccgatcccga catggcgacg gtgggcggca agatgcccga catcggcaac
    45001 gtcgtcgaga acaactacaa gccgctggtg ctgcgcctgc agaacctgcg cgtgcccacc
    45061 atcgccgcgg tcaatggcat cgccgccggc gccggcgcca gcgtggcgct ggcctgcgac
    45121 ctggtggtgg cgacgaagtc ggcctccttc ctgcaggcct tcagcaagat cggcctggtg
    45181 cccgacaccg gcggcacctg gttcctgccg cagcgtgtgg gcatggcacg cgcgatgggc
    45241 ctggcgatgc tggccgacaa gctgcccgcc gagaaggccg ccgactgggg cctgatctgg
    45301 gcggcgtacg acgacgccga attcggcgcc agggtcgacg cgctcgcggc gcaactggcg
    45361 gccatgccga ccaaggcgct ggtgcgcacc cgccaggcga tgcacgccgc ggccggtcac
    45421 acgctcgaac agcagctctc cttcgagggc ggcttcatgc gcgagctggg ctggagcccg
    45481 gactacgccg aaggcgtcgc cgccttcatg gaaaagcgcg caccgaagtt caccggggaa
    45541 tgagcgtgac cgatatcgag acctccacgc ctgcagtgca gcccctgccg ccctcggccg
    45601 tcatcgccgt ggtcggcacc ggcgccatgg gcgccggcat tgcccaggtg gcggccgcgg
    45661 ccggccacgt ggtcaagctg ctcgacaatc gcccgggcgc cgccgccaag gcgatcgagg
    45721 gcatccgcgc ccagttcggc aagctcgccg acaagggcaa gctgagcgcc gaagccgcgc
    45781 aggcggcggg cacgcgcctg gtcgccgtcg agcagctcgc cgagctggcc gacgccgcgc
    45841 tggtggtcga ggccatcgtc gagaacctcg aggccaagca gaagctgtat cgcgacctcg
    45901 aggacatcgt cggcgccgac tgcatcttcg gcaccaacac ctcgtcgatc tcggtgacct
    45961 cgatcggcgc cgccctgcag cgccccgagc gcctcgccgg cctgcacttc ttcaacccgg
    46021 cgccgctgat gaagctggtc gagatcgtcg ccggcctcgc caccgcgcgc agcgtcgccg
    46081 acaccctgtt cgcgaccgcg gcagcctggg gcaagacgcc ggtgcacgcg cgctcgacgc
    46141 cgggcttcat cgtcaaccgc gtggcccgcc cctattacgc cgaggcgctg cgcatcctca
    46201 acgagggtgg cagcgactgc gccacgctcg acgcgatcct gcgcgacgcc ggcggtttcc
    46261 gcatgggccc gttcgagctc atggacatga tcggccacga cgtcaatttc gccgtcacgc
    46321 gctcggtctg gaacgccttc tacaacgacc cccgcttcac cccctcgctg atccagcagg
    46381 agctggtcga cgccggcttc tacggccgca agtcgggccg cggcttctac gactaccgcg
    46441 aaggcgcggc gcggcccgca ccccacgtcg cggtggccca gaacgcaccc gacgagatcg
    46501 tgctgcacgg ccattccgcc gcggtgcatg cgctcgccga ccggctcttc gagcgcaaca
    46561 tcccgcacac ctggggcgag gccaacgatg gtcgcatcgc cgagacgggc ggcgcggtga
    46621 tcttcgtcac cgacggccgc accgccaccc agcgcgccgc cgagatgggg atcgccaatg
    46681 tggtgctgat cgacctcgcg ctggactacg ccaccgcacc ccgcatcgcg gtgggcgccg
    46741 cgatcaactg cttcgcgccc gccgtcggcg ccgcgatcag cctgctccag gccgccggct
    46801 tcgaggtctg ccggctgggc gacacgccgg gcctggcggt gatgcgcacg gtggcgatgc
    46861 tcgccaacga ggcggccgac gcggtcagcc agggcgtgtg cgacgctgcc ggcgccgatg
    46921 cggcgatgaa gctcggggtg aattacccgc gcggaccgct ggaatgggcc gaccgcgtcg
    46981 gcctgccggt gatcggcgcc gtgctctcca acctcgcccg cttctacggc gaggaccgct
    47041 atcgcgtatc gccgctgatc cagcagcgcg tcttcgccgg aaagaagatc catgactgac
    47101 gtgcagcccg tccccaccga tccgcaagcc cttgccgagg ccgtcaccgc ggcgatgtgg
    47161 tcgcgcgatc gcaccgccca gtcgctcggc atgcgcatcg agtccgtcgg ccccggccgc
    47221 gccaccgtgc gcatgacggt gcgcggcgac atggtgaatg gccatcacat ctgccacggc
    47281 ggcctcatct tcaccctcgc cgacactgcc ttcgcgtacg cctgcaacgc ctacaaccgc
    47341 aacaccgtgg cgtccggatg caacatcgac ttcgtcgcca ccgggcgcga gggcgacacc
    47401 ttgcaggccg aggccgtgga gcgcaccctc gccggacgca ccggcgtcta cgacgtcacc
    47461 gtgcgcgaca gcgcaggcaa cacgatcgcc ctgttccggg gcaagagcta ccgcatctcc
    47521 ggcgaggtga tcgccggact cgccgcagag aacgcctaga cgggtccgcg cggccccacg
    47581 cacaaccaga gagagacaga ggagaccac
//
LOCUS       DAOTIN010000016        44636 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_863_length_44636_cov_9.470088, whole genome shotgun sequence.
ACCESSION   DAOTIN010000016 DAOTIN010000000
VERSION     DAOTIN010000016.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 44636)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 44636)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44636
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_863_length_44636_cov_9.470088"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(323..1648)
                     /locus_tag="P5537_04235"
     CDS             complement(323..1648)
                     /locus_tag="P5537_04235"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002931806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HRV77286.1"
                     /translation="MNFENLGLAEELLKAVASTGYTTPTPVQQRAIPAAIAGRDLLVS
                     SHTGSGKTAAFTLPALNRIIDRRPAPGSGPRVLVLTPTRELAQQVEKAVQTYGKALRW
                     LNTACLVGGAPMFAQIKQLQRQCDVVVATPGRLLDHLNRRKIRLSDVEVLILDEADRM
                     LDMGFAEDIDAIVAATPGKRQTLLFSATLDGVVGNMATRMTRDAERIEIEVAQEDRGQ
                     IEQRLMFADDLGHKNRLLHALLGDDGMNQAVVFTATKKSADELSLALQEKGIAAAALH
                     GDMHQTQRNRTLDRLRQGRIGVLVATDVAARGIDVAGISHVINFDPPRQAEDYVHRIG
                     RTGRAGRDGIAITLSGPRETGLIRAIERFTGDRLAVHTIPGMEPSPRKPAGPRPGGNG
                     GRRFGSGAKPGGGSYGRPGGDARRSGGGFSRDGHPSRSERSHGDRRSRG"
     gene            complement(2204..2482)
                     /locus_tag="P5537_04240"
                     /pseudo
     CDS             complement(2204..2482)
                     /locus_tag="P5537_04240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011764050.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
     gene            2700..3875
                     /locus_tag="P5537_04245"
     CDS             2700..3875
                     /locus_tag="P5537_04245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77287.1"
                     /translation="MSTQDSSGDDPIRVLATHAGGKILAVSLHLPERAWMGGAVIGMA
                     PAEGVEHLRQHASHSPQAHAHALALACALAAGEPPPEKAERLRTERRLAAEMIDMHLR
                     RLLVDWPPSLGFEPRTNRYGEFHRRLLHAGEHENDFLLGGEVLDLVARELLAGFFNQI
                     RMPHGIGEFLDRLAGGGSLSSVLGELIAQGPSTVPPERRTALLGTLSADAWATAVGTW
                     PNAEFIHHPRYAGEAAETGPLARHAASPLVRILLERGNRISARLFAKAIDVADCASTM
                     RHPGSEEVAPLIDACRPAPEVGLARVITARGALLCWVRLAEGRIADCAIVPAGAWNLQ
                     PDGVYCREAMCLHAADGNPEALKRMLEWLMLAIDPSLPFVVELVAAAEDAGAAPASA"
     gene            complement(3972..4472)
                     /locus_tag="P5537_04250"
     CDS             complement(3972..4472)
                     /locus_tag="P5537_04250"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004376916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HRV77288.1"
                     /translation="MTQQQASGEDFQRRFRNALGMFATGITVVTARTPAGEPIGLTVN
                     SFNSVSLDPPLIVWSLANELPGRPLFEGCEYYAINVLAEDQADLSQRFASRLGEKFAG
                     LEFDSGIGGVPLLAGCCARFQCRNTVRHAGGDHVVFISEVVDFDRAEERLPLLYFGGA
                     YRQLRA"
     gene            4594..5676
                     /gene="mutY"
                     /locus_tag="P5537_04255"
     CDS             4594..5676
                     /gene="mutY"
                     /locus_tag="P5537_04255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HRV77289.1"
                     /translation="MSDFSTRLIAWQREHGRHDLPWQGGHDPYRIWLSEIMLQQTRVE
                     TVIPYYERFLARFPDVAALAAAPVEDVMALWSGLGYYARARNLHRAARVIMDEHGGAF
                     PHSAAAIAGLPGIGRSTAAAIAAFARGERVAILDGNVKRVLCRVFGIEGFPGEKAVET
                     RLWALAESLLPERGIGRYIQAQMDLGATLCTRARPACARCPFHDDCVARREGRVAELP
                     AARPKKVVPRRGARCAVILHQGAVLLERRPPAGIWGGLLALPELPTEAEDAQAWSAQR
                     FGLATAAPQPLAPLTHAFTHFVLELQPLLLHTHSIHGLADDGALCWLPLGAHAEAALP
                     TPVRRILDELARPGLFDAGTAAPRSI"
     gene            complement(6088..6690)
                     /locus_tag="P5537_04260"
     CDS             complement(6088..6690)
                     /locus_tag="P5537_04260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LON peptidase substrate-binding
                     domain-containing protein"
                     /protein_id="HRV77290.1"
                     /translation="MTPPPDTLPLFPLKTVLFPGGVLPLRVFEPRYMDMVTRCMREHT
                     PFGVCLIAAGEEVGEAAVPHPVGTEALIERWDMEQPGVLELLVRGGRRFRIVDHELER
                     DGLLVGSVRWLEEPPAEPVPAAQAELLPLLRSIVEELGDRLPPPHDFDDAAWVGARYI
                     ELLPIPLLAKQKLLELDDILSRLEILQQFLRDHGLLPKKA"
     gene            complement(6731..7357)
                     /locus_tag="P5537_04265"
     CDS             complement(6731..7357)
                     /locus_tag="P5537_04265"
                     /EC_number="2.5.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0106141 - flavin prenyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin prenyltransferase UbiX"
                     /protein_id="HRV77291.1"
                     /translation="MTPPRTITVAFTGASGLPYGVRLVECLLQAGCRVWLLYSQVAQI
                     VARQEMDWNLPARPAEVEAELSARFAAAPGQLRVFGREEWFAPPASGSNPPDAMVVCP
                     CTVATLASIAGGLSQNLIERAADVVIKEGRKLVLVPRETPYSALHLENMLKLARLGVC
                     ILPPNPGFYHHPQTVQDLIDFVVARILDQLGVPHSLMARWGEDRERAG"
     gene            complement(7676..8842)
                     /locus_tag="P5537_04270"
     CDS             complement(7676..8842)
                     /locus_tag="P5537_04270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004376924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HRV77292.1"
                     /translation="MNALRRLALALASSLSLACALPAAAAGVSADEIVVGTVSDLSGP
                     IAMLGVPVRDGMLMRFDEANAAGGVHGRRIRLAVEDAGYDPKRAVLAARKLVQHDQAF
                     AFIANMGTPVVMASMPIIVDAGRLHLFPFSPHRATYEPLHPLKFQNFAPYQDYMEAAT
                     RHMVRERGYQRSCLLYQDDDYGLEVMKGVEKALAGLGSELVERTSYKRGATDLSSQVA
                     RLRAARCDLVVLATVVRETVAAMSEARKIGWNVDMLVTASGYSAQTHELGGAAVEGLY
                     GVSVLPHPYAEGANSQLAAWIERYRARFKAEPNVWSVMGYTLADLFVRTAEATGRELT
                     PERFARTLEGMAFTRDYFGSPAYRFSADDHLGNRKGRLAQIRNGRWELITDYLD"
     gene            complement(8954..9175)
                     /locus_tag="P5537_04275"
     CDS             complement(8954..9175)
                     /locus_tag="P5537_04275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77293.1"
                     /translation="MSAWSCPHDLNGICQRVRGAICSPGMRGCELEGKVRFALDELNA
                     PRKPVKARPAEVKPEPKPSTPAPRRRLPF"
     gene            complement(9324..10292)
                     /locus_tag="P5537_04280"
     CDS             complement(9324..10292)
                     /locus_tag="P5537_04280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HRV77294.1"
                     /translation="MSAALSRGAGAAVRAALPWLAVLLLALAWLGTDYALGKATLVAT
                     YAIAGLGVVVVVGQAGQIALGQAALVALGAYAQALLVARGVPAPLALPAAAAAGALGG
                     ALASLPARRLGGLYFGMSTLAFALIVEEALARWESLTYGAAGLAVGAFAFAGWRADST
                     LAQAAVSVAALALALLACARLLASRHGRAWRAVRDDELAAAACGIDTDAAKMQAFVVG
                     GALSGLAGGLYAHWIGFISPEQFGLVFSFELLMLAFIGGARRIAGAAWGALVIVAIPP
                     LISLLRDRLPGDWARASGLELLLFGAVIVAVVLLRPAGLAGGGQGR"
     gene            complement(10289..11155)
                     /locus_tag="P5537_04285"
     CDS             complement(10289..11155)
                     /locus_tag="P5537_04285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004386118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HRV77295.1"
                     /translation="MLAFVQVLASGVAIGCVYGLVALSFVLIYKATETVSFMQGDLLM
                     LGAFAALGLHAFAGWPLVVTALAAVLAVGGLGAVLERTVLRRALGQPHLVAVLLTFGL
                     GMMMRGGVASVPAAAQDMHRLPFAADTLAIGPLVLATSHLWVITATVLLAGVLAAFFR
                     HTRTGLALRACSEDARSAALMGIPVARMHTLAWALGAALAAIAGLLLAPITFVHLNMG
                     FIALKAFPAAVLGGLTSLPGALVAGVFLGVAEALAGLALPEGAKDFVPYVLLMAALLL
                     FPQGLGGGRGRA"
     gene            complement(11686..13860)
                     /locus_tag="P5537_04290"
     CDS             complement(11686..13860)
                     /locus_tag="P5537_04290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77296.1"
                     /translation="MSDESKKKGYQWRFFRSGGFDQVRIETADDLRHLGELDQKLWSV
                     LACPTSGLEFDTRTLQLLDVDDDGSIRAPEIIDATRWVCTVLKDPDVLFRGADGLPLA
                     AIDETNAEGARLLATAAKVLAYVGKADAVEISMGDLAETEKLFAPEHQNGDGVVPAEL
                     AGDPRLAGAITRIVDTYGAAEDRSGKPGVDQARVDAFFAAAQEVSDWHAQAEADAATV
                     LPLGDATGAAAAVFEAVREKVEDYFTRCRLAAFDERAAAALNPADTAYAELSLQSLDA
                     ASAAVAALPLALVGAGRALPLAVGLNPAWEARIAALRDQVVIPILGAREALTQAEWED
                     LAGRFAAHRAWVAAMPANPVAVLPVADVRALLADGTCAALTRLIDEDLAAETAAGQVD
                     ALERLVRYNRDLVRLLRNFVTLSDFYSRHDKAIFQAGTLYLDQRSCELCLRVGDMARH
                     ATLAPLSGTYLVYCECQRQGEAPMNIVAAMTGGDADEMMVPGRNGIFYDRQGRDWRAS
                     VVKVVEAPISVRQAFWSPYKRIGRMIGEQLQKFAAARDKAVNDQAATGVAGASAKIEA
                     APAAAAAPAAAPAPFDIAKFAGIFAAMGLALGAIGTALAAVVSAFLGLPVWQMPLVVL
                     GALLVISGPSMLLAWLKLRQRNLGPLLDANGWAVNTRARINIPFGGALTGVAALPPGA
                     SRALTDPYAEKKTPWKSWLFLVLLIAAVVVAWQQGYLDRFLG"
     gene            complement(14050..14691)
                     /locus_tag="P5537_04295"
     CDS             complement(14050..14691)
                     /locus_tag="P5537_04295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002931778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HRV77297.1"
                     /translation="MIQATIVPVTPFQQNCSILWCERTKKAAVVDPGGDLDRILATVA
                     ELGVTVEKILITHGHIDHAGGTAKLARELGVPIEGPQEEDRFWIEGMPQQSKMFGFPD
                     VESFEPDRWLHDGDTVTVGEQTLKVIHTPGHTPGHVVFVHEGARLAIVGDVLFAGSIG
                     RTDFPRGDHQTLIRSIREKLFPLGDDITFIPGHGPTSTFGEERDSNPFVGAYG"
     gene            complement(14847..16190)
                     /gene="gdhA"
                     /locus_tag="P5537_04300"
     CDS             complement(14847..16190)
                     /gene="gdhA"
                     /locus_tag="P5537_04300"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004342699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HRV77298.1"
                     /translation="MKYQSLEEFLAYVEQRNPGQPEFLQAVTEVMESLWPFISANKRY
                     AEHSLLDRLIEPERVIMFRVSWVDDRGEVQVNRGYRIQHSSGIGPYKGGLRFHPSVNL
                     SILKFLAFEQTFKNALTTLPMGGGKGGSDFDPKGRSPGEVMRFCQAFISELYRHVGPD
                     TDVPAGDIGVGGREVGFMAGMMKKLSNNSACVFTGKGLSFGGSLIRPESTGYGTVYFA
                     NAMLERAGRDIKGMRVSVSGSGNVAQYAIEKLMELGAKPITCSDSSGTVIDEAGFTPE
                     KLAILMEIKNHYYGRVAEYAERVGARFEPGVRPWHVPVQVALPCATQNELDGNDAATL
                     VKNGVVAVAEGANMPSTMEAVKIFEHNGVLYAPGKASNAGGVATSGLEMSQNAMRLSW
                     TREEVDARLKEIMLGIHAACLKYGEREDGTVSYVDGANVAGFVKVAEAMLAQGVI"
     gene            16495..16968
                     /gene="lysM"
                     /locus_tag="P5537_04305"
     CDS             16495..16968
                     /gene="lysM"
                     /locus_tag="P5537_04305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004342696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein LysM"
                     /protein_id="HRV77299.1"
                     /translation="MGLFAFIKEAGEKLFGTGEANAAADPAAANAKAAQAIHDYIVAL
                     KIAPPDLGVSFDAAKSLVTVSGTAPDQATREKILLAAGNVAGVAEVENRLSVSRAEPE
                     AQFHTVARGDTLSAIAKKYYGNANQYPAIFEANKPMLSHPDKIYPGQVLRIPPQA"
     gene            17065..17493
                     /locus_tag="P5537_04310"
     CDS             17065..17493
                     /locus_tag="P5537_04310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HRV77300.1"
                     /translation="MARIRIELPDRFAFSTDIPLLMSHINYGNHLDNAQLLGIVSEAR
                     VRFLKSMGYSELDIEGLGIIVADAALQYRSEAFHGETMRVEMGVADFHEHGCDLVWRM
                     AEAASGREVARGKTGIVFFDYGERRKVAVPEGFRRRFAAA"
     gene            17500..18825
                     /locus_tag="P5537_04315"
     CDS             17500..18825
                     /locus_tag="P5537_04315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03862 family flavoprotein"
                     /protein_id="HRV77301.1"
                     /translation="MQHARVAVVGGGPAGLMAAGALAERGCTVTVYDAMPSVGRKFLL
                     AGRGGLNLTHSEPLADFLGRYGDRRDPLAPLVEAFPPQALREWAHGLGVETFVGSSGR
                     VFPNEMKAAPLLRAWLARLRAAGVRFAVRHRWLGWAGEAAQGGPVEDHPAPDAANADE
                     RQPRPQRLRFATREGEQHVEADALVLALGGGSWAKLGSDGAWVAPLRAAGVEVADLLP
                     ANCGFDVAGPAGTGWSAHFLERFRGQPLKSVAARCTDPTGRIHARAGECLISATGIEG
                     GLVYALSAPLRDTLLARGEAILELDLAPGRSLERLAAELARPRGSRSFASHLHSQAGI
                     KGVKAGLLRECVDKAGLDDPARLAAAIKALPLRLLATRPLDEAISSAGGVRFEALDAH
                     LMLRARPGVFVAGEMLDWEAPTGGYLLTACFATGLAAGTAAADWLSHRP"
     gene            18874..19506
                     /locus_tag="P5537_04320"
     CDS             18874..19506
                     /locus_tag="P5537_04320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HRV77302.1"
                     /translation="MNLHPFLVAIEVGGTLAFAMSGLIEATRKRMDIVGVFSVAFVSA
                     FGGGTLRDILLDRRPLFWIENQEYLWLVLAMVATTPLWLQTLRHKVGGRLMELADAFG
                     LGLFAISGATLADAAGMPALVSMMMGVVTAVFGGVSRDVLCNEVPKVYSDHRPYAMCA
                     LFGCGVFLALNATGLPLPITTLAGIATATGSRLLALVFDVRLPAWPAHRD"
     gene            complement(19531..20733)
                     /locus_tag="P5537_04325"
     CDS             complement(19531..20733)
                     /locus_tag="P5537_04325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004265388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HRV77303.1"
                     /translation="MQPVQTSNDVLFILLGAIMVLAMHAGFAFLEVGTVRRKNQVNAL
                     VKILSDFAVSTLAYFFIGYGIAYGVHFFSGAGALVEHHGFELTRFFFLLTFAAAIPAI
                     ISGGIAERARFQPQLAATFLLVGFVYPFFEGIAWNQAFGVQAWLKASFGAEFHDFAGS
                     VVVHAMGGWIALPAVLLLGARRGRYARNGQISAHPPSSIPFLALGAWILIVGWFGFNV
                     MSAQRLENISGLVAINSLMAMVGGTVAALAAGRNDPGFVHNGPLAGLVAVCAGSDVMH
                     PLGALVVGGVAGVLFVVMFTLTQNRWKIDDVLGVWPLHGLCGAWGGLAAGIFGSEALG
                     GLGGVALASQAVMTALGIGVALAGGAAVYGALKLAVGLRLDQEEEFNGADLSIHRITA
                     TAERESNW"
     gene            complement(20979..21311)
                     /locus_tag="P5537_04330"
     CDS             complement(20979..21311)
                     /locus_tag="P5537_04330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002928863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HRV77304.1"
                     /translation="MKIKPVIPREQANQDVDDAIAHYLEEASSSVALGFIDALERGYT
                     HIGRHPGTGSPRHGHELDLPGLRAWALSSYPYLVFYIERPDHIDVWRVLHGQRDIPAW
                     MQDPDTLA"
     gene            complement(21308..21559)
                     /locus_tag="P5537_04335"
     CDS             complement(21308..21559)
                     /locus_tag="P5537_04335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system ParD family
                     antitoxin"
                     /protein_id="HRV77305.1"
                     /translation="MSTMNISLPNSLKSFVDQQVSERGYGTSSEYVRELIRKDQDRQR
                     LRGVLLAGAATAPASPADAAYFEGLRDRVRRAAEPDSRG"
     gene            complement(21888..22331)
                     /locus_tag="P5537_04340"
     CDS             complement(21888..22331)
                     /locus_tag="P5537_04340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF411 domain-containing protein"
                     /protein_id="HRV77306.1"
                     /translation="MKTKTLLGGLLASLMIMSGAGFAQGPVRVEVYKSAYCGCCGKWV
                     EHLRKNGFDVVTKDVDNVPAAREALGMPDQYGSCHTAKVGSYSVEGHVPADDIRRLLS
                     ESPKAIGLATPGMPQGSPGMETSTPQPYETLLVGLDGSAAVFARH"
     gene            complement(22448..23851)
                     /locus_tag="P5537_04345"
     CDS             complement(22448..23851)
                     /locus_tag="P5537_04345"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal sensor histidine kinase"
                     /protein_id="HRV77307.1"
                     /translation="MIRIHSLTARLATLFAVLAAGLLVLVAVLFGRMLDAHFQELDMH
                     ELQGKVSLIRNTLQDVAATGGRPERVEALERSFVGHESVGVLLRDVEGRVLYIIHPEH
                     FTAAQRAGERISGGLADWTVDERPHRGLEARITLPSLGSKEQTIEALVALDLSHHVHF
                     LASVHNATWAGVVVAALAAALLGWFAAHRGLAPLRRVTETARRLSARQLGERLAIDDA
                     PLEVRDHVEAFNGMLARLEAAFQRLGDYSADIAHELRTPISNLMTQTQVALSRPRTLD
                     EYQDILASNLEEYERIARMVSDMLFLAKAEENTLAHAGEAIDLAREADALIDFYEALA
                     EEGQVRIVRQGQASVQGDRLMLRRALSNLISNALRHTPKNGQITIRVDADAAGVRLAV
                     CNVGDPIPADQIERIFERFHRGSAQRESRGEGAGLGLAITRSIVQAHGGHITARSAEG
                     VTCFTITLPRNEASSPS"
     gene            complement(23854..24534)
                     /locus_tag="P5537_04350"
     CDS             complement(23854..24534)
                     /locus_tag="P5537_04350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal response regulator transcription
                     factor"
                     /protein_id="HRV77308.1"
                     /translation="MKILIVEDEVKTGDYLRQGLTEAGFVVDLARDGLDGLHLALAGD
                     YDLIVLDVMLPSLDGWGILQTLRRGGRETPVLFLTARDQVEDRVRGLELGADDYLIKP
                     FAFSEFLARVRTLLRRGRGHEPEILRSANLELDLLRRRVTRCGQRIDLTAKEFALLEL
                     LLRRKGEVLPRSLIASQVWDMNFDSDTNVIEVAVRRLRVKVDDPFEPKLIRTVRGMGY
                     VLEAMEPS"
     gene            24721..25170
                     /locus_tag="P5537_04355"
     CDS             24721..25170
                     /locus_tag="P5537_04355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77309.1"
                     /translation="MKLRLYRLAGLMPVVALAAALHGSPVVAQTTDPAQAWPPAASVP
                     ALQERMKSIRAETDPERRMALMEEQIKALEAASQGTPAGCPMMGGQMGAGPMMKGGGP
                     GPGAGPMGGMMMDPKLMQEHMKMMQEHMGMMQNMMKMHPAAKPAMPN"
     gene            25542..26954
                     /locus_tag="P5537_04360"
     CDS             25542..26954
                     /locus_tag="P5537_04360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HRV77310.1"
                     /translation="MRASLPISLLAATVLTGCASVAIDENFAEVERFAREQTGSEVRW
                     LRSDPEREAMRAEVDRLLAQPLAIDDAVRIALGYSPAFQSLLAEAAVASADATGSARI
                     GNPVFTFERLFRSGAEGRELDIGRSLGISLFDLLFLPARLEQAEFRQQQTRLQSSIAL
                     LSTVTEVRQAWVDAVAARQVARYREEVATAAGTAAELARRMQATGNFSRLQRAREQAL
                     AAEETANLIRARQNATAARETLIQRLGLTPSQAQALRLPDQLPALPEAPMDEATAGAA
                     LLENRLDVRIARTDLDRTAKSLGLTQVTSVVNGLHVAGVRNSETGESSQRGFEVELPL
                     PLFDFGDAARASSEARYLSAFNRTLEVANNASSQVRVAYEGYRSAYDLARHYRSEVVP
                     LRQNITEESVLQYNGMLIGVFELLAAARAQSASVVQAIEAERDFWRAEAALKASLLGQ
                     PIAPISLQSSASPAEAGAGH"
     gene            26972..28375
                     /locus_tag="P5537_04365"
     CDS             26972..28375
                     /locus_tag="P5537_04365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper oxidase"
                     /protein_id="HRV77311.1"
                     /translation="MTTRRSFLAGAGLLAAAGTVNRAALAALPEPVIQTSAATAAPLT
                     PPTGRPYDPVVTLNGWTAPWRMNAGVKEFHLVAEPVEREIAPGMVARLWGYNGQSPGP
                     TIEVVEGDRVRIFVTNRLPEHTTIHWHGQRLPNGMDGVGGLNQPQIPPGKTFVYEFVA
                     RRPGTFMYHPHADEMVQMAMGMMGMWVTHPRAPHPHIAGVDRDFCFLLNAYDIEPGSY
                     VPKINTMLDFNLWTWNSRAFPGIDSLNVRKGDRVRVRIGNLTMTNHPIHIHGHEFQVT
                     GTDGGPTRPESRWPEVTTDVAVGQMRQIEFIADEEGDWAMHCHKSHHTMNAMGHDVPT
                     MIGVDHRGLVEDIQKLVPDYMLMGERGMADMGEMEMPLPDNTLPMMTGQGPFGAVEMG
                     GMFTVLKVRRDQKPGDYRDPGWFRHPKGTVAYEWAGAALPEPARGDAAGASSMPRTAG
                     GPPVEMAVRKPTGHQGH"
     gene            28449..28949
                     /locus_tag="P5537_04370"
     CDS             28449..28949
                     /locus_tag="P5537_04370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin family protein"
                     /protein_id="HRV77312.1"
                     /translation="MKSRRRFLATSLAAGVLAVHRSTFAHGNAEHADNAASDTPKEQQ
                     QWGIAGDAKAVSRAIAIVMTDEMRFVPDRIEVRLGETIRFTHENRGAVMHEMVVGTPK
                     TLAEHAEMMQRFPEMEHDEPWMSHVAPGGRGEMIWHFNRAGDFQFACLIPGHFQAGMI
                     GTIKVG"
     gene            29052..29399
                     /locus_tag="P5537_04375"
     CDS             29052..29399
                     /locus_tag="P5537_04375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-binding protein"
                     /protein_id="HRV77313.1"
                     /translation="MKKTLITTALLALLGGGAPLAFAQADHDAHHGGASAPADANAKL
                     AEGTVKKIDKSAGKLTIAHGPLESLGMPAMTMVFRAAEPGMLDQVKAGDKIRFAVEKV
                     GGALTVTSLEPAQ"
     gene            29534..30841
                     /locus_tag="P5537_04380"
     CDS             29534..30841
                     /locus_tag="P5537_04380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HRV77314.1"
                     /translation="MKSPFAVPSSHLLRPAALALVVALTLGSGSAWTQGSPDTPTLGS
                     SPQALIEYARHSNPGFAAARAEASAAQERVTPAGALPDPTFEVELMDATNTMSGRSAS
                     LLPGQVGETRYRITQPLPGWGKRELAVKAAEAQATQADAMRDTSWAELAAKIETLWLR
                     YYAADRELVLNREGLTLLQSLEALSLTRYELGLLPQQAVLRMQREITAQRLALVEVEQ
                     RRKGLAAGLNGLLGRAHDAPLATPADPAPLPEQLEAGALFESAASANPDVNAAAYGID
                     VARAERERTYQDRLPDFAVGVRNNRPDEGKSSWDVMFEVMIPLQQSSRRAKEREAEYM
                     LMAAEARREDAKARASGELGIAWSMYAQGRETLRLLEHTLLPQAQATRDASQAALSSG
                     KVDFDSVIEAERQLIDIRTQRLKAELDTRLALTEIKKLTGDLK"
     gene            30856..32394
                     /locus_tag="P5537_04385"
     CDS             30856..32394
                     /locus_tag="P5537_04385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HRV77315.1"
                     /translation="MTAIAAGVAIAIGAGYWIAHLQNAGNPVPLISESQAQSDSAAPA
                     DGERKILYYRNPMGLPDTSPVPKKDSMGMDYIPVYADDQPDDSGAVVVSPARIQTLGV
                     KTAEVELRAVDSAVRASGRIEFDERRQVVVAPRFEGWIERLHVNAVGDPVKKGQPLFT
                     AYSPELQSTGEELRIAERLASQNAAHDPLASESSRRLAEATRARLRNLQVAGQAGARQ
                     VFHAPASGVVLEKEAIEGGRFMPGEALFRIADLSKVWIIADVFEQDLARVQVGQSAQV
                     TLEAYPGRGFAARVDYLYPTLDAATRSTRVRLELDNPEGLLRPGMFAQIALAAGDATP
                     RVAVPSSAIIDDGERRVVLIALGEGRFKPQPVKLGQRGRDVVEVLDGVTAGDRVVVSA
                     NFLIDSESQLKAALSNLVEPDARDQAQASPTRYEAQGTFDALDAEGGSVTMTHGEIPA
                     LQWPAMTMDFKLADPALVKDIAPGSAVRFVFEAGEPGEYIITGIEPAASSAAAPAAAG
                     HAGH"
     gene            32411..35635
                     /locus_tag="P5537_04390"
     CDS             32411..35635
                     /locus_tag="P5537_04390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051139 - metal cation:proton antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CusA/CzcA family heavy metal efflux RND
                     transporter"
                     /protein_id="HRV77316.1"
                     /translation="MEPSNAVPTDTAARPAAPGLLDRVIDWSAHNVFLVLLATLFLIG
                     GGVYAVKHTPLDALPDLSDVQVIVYTDYPGQAPQVVEDQVTYPLTTSMLAVPRAKVVR
                     GFSMFGASYVYVIFEDGTDIYWARSRVLEYLSSAAGRLPQGVAPQIGPDATGVGWVYQ
                     YAVLGKDMSLADTRSLQDWYVRYQLTKAQGVSEVASIGGFVREYQVTVDPLRLAGYGI
                     TLDQVTQAIRASNRDVGGRVLELAEKEYMVRGRGYLRSVDDISDIVLKAERGTPVRVG
                     DVARVELVPAERRGIAELNGEGEVASGIVMARFGQNALDVIANVKAKIAEITPGLPAG
                     AEIVPVYDRSELIERAIGNLKWTLLEESLIVAAVCVIFLLHVRSALVAIITLPLGILF
                     AFIAMRSLGLGSNIMSLGGIAIAIGAMVDAAIVMIENAHKHIERLPEGATQPQRAAAI
                     VLACKEVGPALFFSLLIITVSFLPVFALEGQEGRLFSPLAFTKTFAMAGAALLSVTLV
                     PVLMLFFVRGRILPEAKNPVNRLLIWLYRPIIQGVLRFKLLTLVLAVLAMAATIVPAR
                     QIGSEFMPTLNEGTLFYMPAALPGMSVTEAGRLLATTNRIIKTFPEVESVYGKAGRAN
                     TATDPAPLEMFETVINLKPQDQWRPGVTTDTLIAEMDAALKFPGLANSWTMPIKARID
                     MLSTGIRTPVGVKVFGKDLETLEKVAQAVEAAVRKVPGASSAYAERVAGGYYVDIVPR
                     RDQLARYGLTIDMVQDVIATALGGEMVTTTVEGLERYGVSVRYARGLRDDPARLASDV
                     FVPTMNGPIPLGQLAEVKLTRGAPGIRTENALLAAYVYVDTREADLGAFVKRAQQAVA
                     EEVAFPQGYYATWSGQFENMERAKEKMKIVVPFTLALIFVLLYLNFGRLAETLIVMLS
                     VPFALVGGVWLMWWLGYQMSVAVAVGFIALAGVAAETGVIMLIYLDHAWKAVCERRQA
                     EGREAGVADLYEAIMEGAVERVRPKMMTVVAIMAGLLPIMWSTGTGAEVMSRIAAPMV
                     GGMVSSTVLTLAVIPALYALVKQWGLRRSAKTAPAQALVTVSNL"
     gene            35878..36126
                     /locus_tag="P5537_04395"
     CDS             35878..36126
                     /locus_tag="P5537_04395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2933 domain-containing protein"
                     /protein_id="HRV77317.1"
                     /translation="MNTKPAHDPGHPRSVAWYRSPGVIAGLMLAAIALFFLLREHWAH
                     VSGNWVYLILLLCPLMHLFGHGGHHGGHHSNDTDSEKR"
     gene            36128..36526
                     /locus_tag="P5537_04400"
     CDS             36128..36526
                     /locus_tag="P5537_04400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c"
                     /protein_id="HRV77318.1"
                     /translation="MPMTEACLGRGVVIAALSGVLISSAAAQGWKIPQPSPGLMPNPG
                     QGKGLYAQHCAACHGTDLKGSDKGPPMLHKVYEPSHHADIAFQLAVANGVRAHHWQFG
                     DMAPVPGLTPDEVAHVTAFIRGEQRKVGIR"
     gene            36551..38899
                     /locus_tag="P5537_04405"
     CDS             36551..38899
                     /locus_tag="P5537_04405"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HRV77319.1"
                     /translation="MTHEHSQGGHSGHNHHHDHASPGQDTDPVCGMTVKPDSPYRVIH
                     AGHEYRFCSAKCQGKFETDQARYLAPEIGQPSTEPALLPGTEYTCPMHPEIRKTGPGT
                     CPKCGMTLEPVMPGLEDEDNPELADFRRRFWGTLPLTVIVTAIAMSGGLFDSMLGDTR
                     PWVELALATPVVLWSGWPFFVRCAQSIGNRSPNMWTLIGLGTGAAYVYSVVATVTPET
                     FPDSFRMGEHVAVYFEAAAVIISLTLLGQVLELKARSETGAAIKALLGLAPKTARRIR
                     ADGTEEDIPLTHVHPGDRLRIRPGEKVPVDGSVDEGESAVDESMLTGEPIPVTKRPGD
                     KVIGATLNTSGALVMVAEKIGAQTMLSQIVQMVAQAQRSRAPMQRLADVVAGWFVIVV
                     VLIALTTFVVWGLFGPQPSWAYGLINAVAVLIIACPCALGLATPMSVMVATGKAATQG
                     VLFRDAAAIESLRKVDTLIVDKTGTLTEGRPAFHSVVAAPGGTEADVLRIAASLDQGS
                     EHPLAQAIVTEARARGLALSTPDTFESSSGIGVRGTVDGQRVVLGNTALMDDERIDWR
                     GLAERAEALRLEGASVMYLAAEGVLVGLIAVADPIKASTPEALDALRASGLRIIMATG
                     DGLTTARAVGARLGIDEVYGEVKPADKNELVGKLQAEGRIVAMAGDGINDAPALARAN
                     VGIAMGTGTDVAMNSAHLTLVKGDLRGIATARRISVATVRNMHQNLVFAFLYNAAGVP
                     IAAGVLYPAFGLLLSPLIAALAMSFSSASVVGNALRLGRKRV"
     gene            39017..39271
                     /locus_tag="P5537_04410"
     CDS             39017..39271
                     /locus_tag="P5537_04410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2933 domain-containing protein"
                     /protein_id="HRV77320.1"
                     /translation="MKAETEVEPVPPERAESSSRVRRVFLVFVVLAAVLLIAEHRLHV
                     LGYLPWLILLACPLMHVFMHRGHGHKGKHTPTEDQGNHDA"
     gene            39289..39918
                     /locus_tag="P5537_04415"
     CDS             39289..39918
                     /locus_tag="P5537_04415"
                     /EC_number="2.1.1.100"
                     /EC_number="2.1.1.334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxylmethyltransferase
                     family protein"
                     /protein_id="HRV77321.1"
                     /translation="MNETSSYGLWSLVIINSLFFIAFAFSFTRPRTSRDWRSLGAYSA
                     FILALFTEMYGFPLTIYLLSGWLSSKFPGIDFFAHDSGHLLEVMFGWSSNPHFGPFHL
                     LSTLFIVGGFWLLAKAWPVLLEAQRTRRVADSGPYARIRHPQYVAFVLVMFGFLLQWP
                     TLITLIMFPVLLIVYARLARREELDAIEAFGDAYRSYRERTPAFIPRLR"
     gene            complement(40143..40421)
                     /gene="copK"
                     /locus_tag="P5537_04420"
     CDS             complement(40143..40421)
                     /gene="copK"
                     /locus_tag="P5537_04420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic Cu(I)/Cu(II)-binding protein CopK"
                     /protein_id="HRV77322.1"
                     /translation="MLKKALMVAALGIATTSAFAVDVERVEKSIPMKDGSTVYIFKDG
                     KMGMEDKMGRAVRMKHGEVMETKDGQKIMMHGDEVMRLDSILRHDSRS"
     gene            complement(40534..40929)
                     /locus_tag="P5537_04425"
     CDS             complement(40534..40929)
                     /locus_tag="P5537_04425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004265710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CzcE family metal-binding protein"
                     /protein_id="HRV77323.1"
                     /translation="MKKSIIAVLAVSAISSLGSSAAFAHEDYSKRGTLHWLEHVQARA
                     SSPTERELATYGYASNATPSRTVIVNADTRYINVTRLETVALKVGDKTINWTFDTLGT
                     NSFPLSKVVQGGDKVTVYLEESPLYRSGS"
     gene            41498..41908
                     /locus_tag="P5537_04430"
     CDS             41498..41908
                     /locus_tag="P5537_04430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77324.1"
                     /translation="MTVFASSSVFSRKIARMLVRGVIGLLMLSHALFAFSSAISLSHD
                     PLRASTHAQAFADADTGQDDHGHRHDDFEDEGGPHQHGHNPADHSHDKPNVPPTHAMG
                     IPPLSDQWLADERRPAYPAPCALLERPPKRLLIV"
     gene            41972..42706
                     /locus_tag="P5537_04435"
     CDS             41972..42706
                     /locus_tag="P5537_04435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HupE/UreJ family protein"
                     /protein_id="HRV77325.1"
                     /translation="MTHSFPSRGRAAVLPCSGPLLHAFTGVLLYLLLTAFAHAHGVAE
                     GDKGYIQEISGTHLLPFTYLGAKHMVTGYDHLLFLAGVIFFLYKLKDIALYVSLFAIG
                     HSVTMLYGVYAGVNVNAYLIDAIIGLSVVYKALDNLGAFQRWFGVQPNTKVATLVFGL
                     FHGFGLAAKIQEFEIARDGLLPNLLAFNVGVEIGQLLALGAILIAMGFWRRTAGFFQH
                     AYTANVAMMCAGFMLIGYQLTGLFVS"
     gene            42727..43413
                     /locus_tag="P5537_04440"
     CDS             42727..43413
                     /locus_tag="P5537_04440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transmembrane anchor protein"
                     /protein_id="HRV77326.1"
                     /translation="MYNTDLPKRADLPTTGKLLRSTALAALIAGGLLVTTVLPAEYGI
                     DPTGIGRALGLTPMGEIKMSLAAEARAEERVATETAPAQPVAVAPTVRAEAAPVPAPA
                     PVAVAALPPAAVAPEPVAGRQDTVTVTLKPGQGAEVKLTMNKDSRVRYEWASAGGPVN
                     FDTHGDPYDAPKNFYHGYGKGRNELGNQGDLVAAFDGKHGWFWRNRSGFDVTVTLKTQ
                     GDYTKIERVL"
     gene            43485..44528
                     /locus_tag="P5537_04445"
     CDS             43485..44528
                     /locus_tag="P5537_04445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HRV77327.1"
                     /translation="MNNIYVIHALLAAALFGASTPFAKLLVGEMSPWLLAGLLYLGSG
                     LGLAASRLIRDRSWTPSGLAEGEWRWLLGAIFFGGVLGPLALMFGLTRTSAATASLLL
                     NLEAVLTAAIAWVVFRENTDRRIVLGMLAIVAGGVVLSWSGGEEGANDWIGPLAIAAG
                     CLCWAIDNNLTRRVSASDALFIAATKGAVAGTVNVGLAFALGASLPDGAVLLGTMVVG
                     LFGYGISLVLFVLALRGLGTARTGAYFSTAPFIGAAVSLVLLGESTSSAFWIAAALMG
                     WGVWLHLTEHHEHEHTHEPMEHGHRHTHDEHHQHEHDFAWNSDEPHEHWHRHEGLVHK
                     HPHFPDIHHRHSH"
BASE COUNT         7219 a        15233 c        15186 g         6998 t
ORIGIN      
        1 gccgccgctc ctacagaggg cggaggcgcg gcggttcatg taggagcgcc ggcaggcgcg
       61 aaggcggggg tgcggtgcgg tatgcgcgtc atttcttccg attgccgaat tcgcagctac
      121 cgcagctcct acgggcgagc cggggcgctc ggtcgtttgt gcaggagcgc cggcaggcgc
      181 gaacgggacg gcgaacgcca ccccggcccc gcggccggat cgaaggcgcg cacgccctgc
      241 cgcagcgcgg gtgaacggaa aaagaccgcg acttccgtcg cggtcttcgt cgttgcatca
      301 ggccctgtcc ggccccgccg gatcagccgc gcgagcggcg gtcgccgtgg ctgcgctcgc
      361 tgcgcgaggg atggccgtcg cggctgaagc cgccaccgct gcggcgcgca tcgccgccgg
      421 gacggccgta gctgccgccg cccggcttgg cgccgctgcc gaagcggcgg ccgccgttgc
      481 cacccgggcg cggtccggcc ggcttgcgcg gcgagggctc catgccgggg atggtatgca
      541 ccgcgaggcg gtcgccggtg aagcgctcga tcgcgcggat cagcccggtc tcgcgcggac
      601 ccgacagcgt gatcgcgatg ccgtcgcggc cggcgcggcc ggtacggccg atgcggtgga
      661 catagtcctc ggcctggcgc ggcgggtcga agttgatgac gtggctgatg ccggcgacgt
      721 cgatgccgcg ggcggccacg tcggtcgcca ccagcacgcc gatgcggccc tggcgcaggc
      781 ggtcgagggt ccggttgcgc tgggtctggt gcatgtcgcc gtgcagcgcg gcggcggcga
      841 tgcccttctc ctgcagcgcg agcgagagct cgtcggcgct cttcttggtg gcggtgaaca
      901 ccaccgcctg gttcatcccg tcgtcgccga gcagggcatg gagcaggcgg ttcttgtggc
      961 cgaggtcgtc ggcgaacatc aggcgctgct cgatctggcc gcggtcttcc tgggcgacct
     1021 cgatctcgat gcgctcggcg tcgcgcgtca tgcgcgtcgc catgttgccc accacgccgt
     1081 cgagcgtggc cgagaacagc agggtctggc gcttgcccgg agtggcggcg acgatcgcgt
     1141 cgatgtcctc ggcgaagccc atgtcgagca tgcggtcggc ctcgtcgagg atcagcacct
     1201 cgacgtccga cagcctgatc ttgcgacggt tgaggtggtc gagcaggcgg ccgggggtgg
     1261 cgacgacgac gtcgcactgg cgctgcagct gcttgatctg cgcgaacatc ggcgcgccgc
     1321 cgaccaggca ggcggtgttg agccagcgca gggccttgcc gtaggtctgc accgccttct
     1381 cgacctgctg ggcgagctcg cgggtggggg tcagcaccag cacgcgcgga ccgctgcccg
     1441 gcgccggacg gcgatcgatg atcctgttca gggcgggcag ggtgaaggcg gcggtcttgc
     1501 cgctgccggt gtggctggac acgagcaggt cgcggccggc gatcgccgcc gggatggcgc
     1561 gctgctgcac cggcgtcggg gtggtgtagc cggtgctggc gacggccttg aggagctctt
     1621 cggcgaggcc gaggttttcg aagttcatgc ttcttcctgt cttgctgtcc gccgcgcggg
     1681 aatgggcggg cggaacgatt cggacccgct gcaggcgggt cgtgatgaca tcacgccgcg
     1741 ccgcgcctgc ggacaggaac ggcacgaggc gtcgcaaggg cgacgggacg cgcgatgggc
     1801 gtggccggcc gatccggcgc cgcatgggcg ccaggaaaga ccgcgcatcg gcaccaaccg
     1861 gttgtcacga tgccagacga tcggaagaac gaatggaaaa cccgacggag tgtcggcgac
     1921 gggaggtcgg aggcgatggg gctgtggtta cagtccctcg ggccgctccg gatcgcgtcc
     1981 ctcgacgcgg cggtattgct ctcggccctg ttgctgcatt gcacaacgac aggcagtata
     2041 ccggctgggc gacaggctgt cgcggtttat tttgcgcggg ccgcttcttg cgccgagttc
     2101 ggcagagcgc aaggccggaa tgaaaacggg cccgccccgg cagcatccgg aacaggcccg
     2161 ctggccacgg cgccagacgc gccgcgacgg cttcggtgcg cgcttacttg ttgaccgcgg
     2221 ccttcagcgt ggcgccggcg gtgaacttgg gcacgctcga ggcggcgatt tcgatggtgg
     2281 cgccggtctg cgggttgcga ccggtgcgag cggcacgctg cgacacctcg aaggagccga
     2341 aaccggtgaa ggcaaccttt tcgcccttgg cgagctgctc ggcgatgatg tcgagcacgg
     2401 cggacagcgc gcggtcggcc tgggcgcggt gcacatccag acggtcggcc agggcttcga
     2461 cgaattcacc tttgttcatg cttttcctcg attggtgtgt gagtgggagt tccggaaggt
     2521 ccgttctacg cggcggattc tagcactgtc gcggattctg gggcgtgcgc agcaatgcac
     2581 gctcgcgctt cttcataccg acggcgggca ccgtcgatgc acatccttcc ccgcgaacaa
     2641 caaacctccc cgatacgggt attctccaaa ttgatccaag aatgcagacg agcgacgaca
     2701 tgagcacaca ggacagcagc ggcgacgatc cgatccgggt cctcgccacc catgccgggg
     2761 gcaagatcct ggcggtgtcg ctgcatcttc ccgagcgcgc atggatgggc ggcgcggtca
     2821 tcggcatggc gcccgcggag ggtgtcgagc atctgcgcca gcacgccagc cacagcccgc
     2881 aggcccacgc gcacgcgctc gcgctcgcct gcgcgctggc cgcgggcgag ccgccgccgg
     2941 agaaggcgga gcgcctgcgc accgagcgcc gcctggccgc cgagatgatc gacatgcacc
     3001 tgcgccggct gctggtcgac tggccaccct cgctcggctt cgagccgcgc accaaccgct
     3061 acggcgaatt ccaccgccgt ctgctccacg ctggcgagca tgagaacgac ttcctgctcg
     3121 gcggcgaggt gctcgacctg gtcgcgcgcg agctgctcgc cggtttcttc aaccagatcc
     3181 gcatgccgca cgggatcggc gagttcctcg accgcctcgc cggcggcggc agcctgagct
     3241 cggtgctggg cgagctgatc gcccagggcc cgtccaccgt tccgccggag cggcgcaccg
     3301 cgctgctcgg cacgctcagc gccgatgcct gggccaccgc ggtgggcacc tggccgaacg
     3361 cggagttcat ccaccatccg cgctacgcag gcgaggccgc cgagaccgga ccgctcgcgc
     3421 gccacgccgc ctcgccgctg gttcgcatcc tgctcgagcg cggcaaccgc atctcggcac
     3481 gcctgttcgc caaggcgatc gacgtggccg actgcgcgag cacgatgcgc cacccgggga
     3541 gcgaggaagt tgcgccgctg atcgacgcct gccggcccgc gccggaggtg ggcctggcgc
     3601 gtgtgatcac cgcgcgcggc gcgctgctgt gctgggtccg cctcgccgag ggccgcatcg
     3661 ccgactgcgc gatcgtgccc gcaggcgcct ggaacctcca gcccgacggg gtctattgcc
     3721 gcgaggcgat gtgcctgcac gccgcggacg ggaatcccga ggcgctgaag agaatgctgg
     3781 aatggctgat gctcgcgatc gacccctcgc tgcccttcgt ggtcgagctg gtggccgcgg
     3841 cggaagacgc aggcgcggcg ccggcatcgg cctgagcccg gagcatcgcc gcgcgcaaga
     3901 aggcggcacg cgcagggtcg gcgcggcgcc tgccggcggg cgggcgccgc cacccgccgc
     3961 cagcgcggcc ttcaggcgcg cagctgacgg taggcgccgc cgaagtacag cagcggcaga
     4021 cgctcctcgg cacggtcgaa atcgaccacc tcgctgatga acaccacgtg gtcgccaccc
     4081 gcgtggcgca ccgtgttgcg gcactgaaag cgcgcgcagc agcccgcgag cagcggcacg
     4141 ccgccgatcc ccgagtcgaa ctccagcccg gcgaactttt ccccgagccg gctggcgaag
     4201 cgctgtgaca ggtctgcctg gtcctccgcg agcacgttga tcgcgtagta ttcgcagccc
     4261 tcgaagagcg gacggccggg cagctcgttc gccaggctcc acacgatcag cggcgggtcg
     4321 agcgacaccg aattgaagga attgaccgtg aggccgatcg gctcgccggc gggcgtacgc
     4381 gcggtcacca cggtgatgcc ggtggcgaac atgccgagcg cgttgcggaa gcggcgctgg
     4441 aagtcctcgc cggaagcttg ctgttgggtc atggacggac gggcgcggtg ggccgcgctg
     4501 ctcgaatggg aataaaaacg ggattatcgc cgcgcgcgcg ggcagcgtcg agcgcgcggg
     4561 caaggcaagg caaggcaagg gaccatagcg gacatgagcg acttctccac ccggctgatc
     4621 gcatggcagc gcgagcacgg ccgtcacgac ctgccctggc agggcggcca cgacccctac
     4681 cgcatctggc tgtccgagat catgctgcag cagacccggg tcgagaccgt gatcccctac
     4741 tacgagcgct tcctcgcgcg cttccccgac gtcgccgcgc tcgcggcggc gccggtcgag
     4801 gacgtgatgg cgctatggag cggcctgggc tactacgccc gcgcgcgcaa cctgcaccgc
     4861 gcggcgcggg tgatcatgga cgagcacggc ggcgcgtttc cgcacagcgc ggcggcgatc
     4921 gccggcctgc ccggcatcgg ccgctccacc gccgcggcga tcgccgcctt cgcccggggc
     4981 gagcgcgtgg cgatcctcga cggcaacgtc aagcgcgtgc tgtgccgggt gttcggcatc
     5041 gagggctttc ccggcgagaa ggcggtggag acgcggctgt gggcgctcgc cgagtcgctg
     5101 ctgccggagc gcggcatcgg ccgctacatc caggcgcaga tggacctcgg cgccacgctg
     5161 tgcacccgcg cccggcccgc ctgcgcgcgc tgtcccttcc acgacgactg cgtcgcccgc
     5221 cgcgaggggc gcgtcgccga gctgcccgcg gcacgcccga agaaggtggt gccgcggcgc
     5281 ggcgcgcgct gcgcggtgat cctgcaccag ggcgcggtgc tgctggagcg tcgcccgcct
     5341 gcggggatct gggggggtct gctggcgctg cccgaattac ccaccgaggc ggaggacgcg
     5401 caggcctgga gcgcccagcg cttcggcctc gccaccgccg caccccagcc gctcgctccg
     5461 ctcacccacg ccttcaccca cttcgtgctc gagctgcaac cgctgctgct gcacacccat
     5521 tcgatccacg gcctggccga cgacggcgcg ctgtgctggc tgccgctggg cgcccacgcc
     5581 gaggccgccc tgcccacgcc ggtgcggcgc atcctcgacg agctcgcccg ccccggcctg
     5641 ttcgacgcag ggacggcagc accacgctcg atctagccgc ggctcgggcg ccgggcgtgt
     5701 gcgcggcgtg atcgcccgaa ggttcgcgcc tgccggcgct cctacagcaa ccaccgcgcg
     5761 tcccgacccc gcctgtagga gctgcggcag ctgcgaaccc ggcgctccga cgctcgacgc
     5821 gcgcgcagaa ctccaccgcc gtcttcgcgc ctgccggcgc tcctacagga atcaccgcgc
     5881 gtcccggccc cgcctgtagg agctgcggca gctgcgaacc aggccatgga gagaccactc
     5941 tcgccgacgc agacggacgc cgtcttcgcg cctgccggcg ctcctacagg aaccaccgct
     6001 cgtccccgac ccgcctgtag gagcggcggc agccgcgaac gcttgctgcg cgctcgcacg
     6061 tgcatcggcg cggcaggggc ctgtgagtca ggccttcttc ggcagcagac cgtgatcacg
     6121 caggaactgt tgcaggatct ccagccggct gaggatgtcg tcgagctcga gcagcttctg
     6181 cttggcgagc agggggatgg gcaagagctc gatgtagcgc gcgcccaccc aggcggcgtc
     6241 gtcgaagtcg tgcggcggcg gcaggcggtc gccgagctcc tcgacgatcg agcgcagcag
     6301 cggcaggagc tcggcctgcg cggcgggcac cggctcggcg ggcggctcct ccagccagcg
     6361 cacgctgccc accagcaggc cgtcgcgctc gagctcgtgg tcgacgatgc ggaagcgcct
     6421 tccgccgcgc accagcagct cgagcacgcc gggctgctcc atgtcccagc gctcgatcag
     6481 cgcctcggtg cccacggggt ggggcaccgc ggcctcgcca acctcctcgc cggcagcgat
     6541 caggcacacg ccgaaggggg tgtgctcgcg catgcagcgc gtgaccatgt ccatgtagcg
     6601 cggctcgaac acgcgcagcg gcagcacgcc accggggaac agtacggtct tgagcgggaa
     6661 cagcgggagg gtgtcgggcg gcggggtcat ggggcgctcc ggtgggcagg cgcagccgcg
     6721 ccggcgggct tcagccggcg cgctcgcggt cctcgcccca gcgcgccatc aggctgtgcg
     6781 gcacgccgag ctggtcgagg atgcgggcga cgacgaagtc gatcaggtcc tgcacggtct
     6841 gcgggtggtg atagaagccc gggttgggcg gcaggataca cacgccgagg cgggcgagct
     6901 tgagcatgtt ctcgaggtgg agcgccgagt acggcgtctc gcgcggcacc agcacgagct
     6961 tgcggccttc cttgatgacg acgtcggcgg cgcgctcgat gaggttctgg ctgagcccgc
     7021 cggcgatcga ggccagcgtg gcgacggtgc acgggcacac caccatggcg tcgggcgggt
     7081 tggagccgga ggccggcggg gcaaaccact cctcgcggcc gaacacgcgc agctgcccgg
     7141 gggcggcggc gaagcgggcg gagagctcgg cctcgacctc ggccgggcgc gcgggcaggt
     7201 tccagtccat ctcctggcgg gcgacgatct gcgcgacctg cgagtacagc agccacaccc
     7261 ggcagcccgc ctgcagcagg cattcgacca ggcgcacgcc gtagggcagg ccggaggcgc
     7321 cggtgaaggc gacggtgatc gtgcggggag gcgtcatcgg ggtgcgggac ggtcgacgga
     7381 tggcgtgaag cgtaacccat ccagcgggcg aggtgcgcgg cgcggggggc gcagcttcga
     7441 tacggtggca ttcgcgcctg ccggcgctcc tacagaaacc accgctcgtc ccgagcccgc
     7501 ctgtaggcgc tgcggcagct gcgaacccgg cggttcgaaa acgacgcgcg tgcagaactg
     7561 cgccgccggt ttcgcgcctg ccggcgctct tacagaaacc accgctcgtc ccggacccgc
     7621 ctgaaggcgc tgcggcagct gcgaaccggg tgctccgggg ctcgacgcgc gcgcatcaat
     7681 ccaggtagtc ggtgatcagc tcccagcgac cgttgcggat ctgggcgagg cggcccttgc
     7741 ggttgccgag gtggtcgtcg gcgctgaagc ggtaggcggg gctaccgaag tagtcgcggg
     7801 tgaacgccat gccttcgagg gtgcgcgcga agcgctcggg cgtgagttcg cggccggtgg
     7861 cctcggcggt acgtacgaag aggtcggcca gggtgtagcc catcacgctc catacgttgg
     7921 gctcggcctt gaagcgcgcg cggtagcgtt cgatccaggc ggcgagctgg ctgttggcgc
     7981 cctcggcgta cgggtgtggc agcaccgaca cgccgtacag gccctcgacc gcggcgccgc
     8041 cgagctcatg cgtctgcgcc gaatagccgg aggcggtgac gagcatgtcg acgttccagc
     8101 cgatcttgcg cgcctcggac atcgcggcca cggtctcgcg caccacggtg gcgagcacca
     8161 cgaggtcgca gcgcgcggcg cgcagacgtg cgacctggct ggagaggtcg gtggcgccgc
     8221 gcttgtagct ggtgcgttcg acgagctcgc tgccgagccc ggcgagcgcc ttctcgaccc
     8281 ccttcatgac ctccaggccg tagtcgtcgt cctggtagag caggcagctg cgctgatagc
     8341 cgcgctcgcg caccatgtgg cgggtggcgg cctccatgta gtcctggtag ggcgcgaagt
     8401 tctggaactt gagcgggtgc agcggctcgt aggtggcgcg gtgaggcgag aaggggaaca
     8461 ggtgcaggcg gccggcatcg acgatgatcg gcatgctcgc catcaccacc ggcgtcccca
     8521 tgttggcgat gaaggcgaag gcctggtcgt gctgcaccag cttgcgcgcg gcgagcaccg
     8581 cgcgcttggg atcgtagccg gcgtcctcga ccgcgaggcg gatcctgcgc ccatgcacgc
     8641 cgccggcggc gttggcctcg tcgaagcgca tcagcatgcc gtcgcgcacc ggcacgccga
     8701 gcatggcgat cgggccggag aggtcggaca cggtgccgac gacgatttca tcggcgctca
     8761 cccccgccgc ggcggcgggc agggcgcagg cgagggacag cgaggaggcg agcgcgagcg
     8821 caagccgacg caaggcgttc atcgggggaa ctcctggagg gtggttggac ggcgcgcggc
     8881 tacggcctgg cgacggcggg acgcgcgcgc gggtggcccg aaggccggac cggggggtga
     8941 tgcggggcgc ggatcagaaa ggcagacggc ggcgcggggc gggcgtgctc ggcttgggct
     9001 cgggcttcac ctcggccggg cgcgccttca ccggcttgcg cggcgcgttg agctcgtcga
     9061 gcgcgaagcg caccttgcct tcgagctcgc agccgcgcat gcccggcgag cagatcgcgc
     9121 cgcgcacgcg ctggcagatt ccgttgaggt cgtgtgggca actccaggca ctcatggcgg
     9181 gctccggcac aaactgcatt cataattacg agagcgttac tatcgtctgc cgcagcgcaa
     9241 gaagcaagct tgtcacgctc cccggtgcaa tcgcacgaaa gggtgggcgc ggctcgagcc
     9301 cgcccgttcg tacgatcgcc ctctcagcgg ccctgcccgc cccccgccag cccggccggg
     9361 cgcagcagca cgaccgcgac gatcaccgcg ccgaacagca gcagctcgag cccggaggcg
     9421 cgcgcccagt cgccgggcag gcggtcgcgc agcagcgaga tcagcggcgg gatggcgacg
     9481 atcaccagcg ccccccaggc cgcgccggcg atccggcgcg cgccgccgat gaaggcgagc
     9541 atcagcagct cgaaggagaa caccaggccg aactgctccg ggctgatgaa gccgatccag
     9601 tgcgcgtaga gcccgcccgc cagcccggac agcgcgccgc cgaccacgaa ggcctgcatc
     9661 ttcgccgcgt cggtgtcgat gccgcaggcc gcggcggcga gttcgtcgtc gcgcaccgcg
     9721 cgccaggcac ggccgtggcg cgaagccagc aggcgcgcgc atgccagcag cgccagcgcc
     9781 agcgccgcga cgctgaccgc agcctgcgcc agggtggagt ccgcgcgcca gccggcgaac
     9841 gcgaaggcgc ccaccgccag gccggcggcg ccgtaggtga gcgactccca gcgcgcgagc
     9901 gcctcctcga cgatgagggc gaaggcgagc gtgctcatgc cgaaatacag cccgcccagc
     9961 cgccgcgccg gcaggctggc gagcgcgccg ccgagcgcgc cggcggcggc cgcggcgggc
    10021 agggccagcg gcgccggcac gccgcgcgcg accagcagcg cctgcgcata ggcgccgagc
    10081 gccacgagcg cggcctgtcc gagcgcgatc tgccccgcct gccccaccac cacgaccacg
    10141 ccgaggccgg cgatggcgta ggtcgccacc agggtcgcct tgccgagcgc gtagtcggtg
    10201 cccagccagg cgagcgcgag cagcagcacc gcgagccagg gcagcgcggc gcgcacggcc
    10261 gccccggcgc cgcgcgacag ggccgcgctc acgccctgcc ccgcccgccg ccgagcccct
    10321 gcgggaacag cagcagcgcc gccatcagca gcacgtaggg cacgaaatcc ttcgcgcctt
    10381 cgggcagcgc cagcccggcg agcgcctcgg cgaccccgag gaagacgccg gccacgagcg
    10441 cgcccggcag gctggtcagc ccgcccagca ccgcggcggg gaaggccttc agcgcgatga
    10501 agcccatgtt cagatgcacg aaggtgatcg gcgcgagcag cagcccggcg atcgcggcga
    10561 gcgccgcgcc gagcgcccac gccagggtgt gcatgcgcgc caccgggatg cccatcagcg
    10621 cggcgctgcg cgcatcctcc gagcacgcgc gcagcgccag cccggtgcgg gtgtggcgaa
    10681 agaaggcggc gagcacgccg gcgagcagca cggtggcggt gatcacccac aggtggctgg
    10741 tggcgagcac cagcgggccg atcgccagcg tgtcggcggc gaagggcagg cggtgcatgt
    10801 cctgcgccgc cgccggcacc gaggcgacac cgccgcgcat catcatgccc agcccgaagg
    10861 tgagcagcac cgccaccagg tggggctggc cgagcgcacg ccgcagcacg gtgcgctcga
    10921 gcacggcgcc gagcccgccc accgccagca ccgccgccag cgccgtaacg acgagcggcc
    10981 agcccgcgaa ggcgtgcagg ccgagcgcgg cgaaggcgcc gagcatcagc agatccccct
    11041 gcatgaagct gaccgtctcg gtggccttgt agatgaggac gaaggacagc gcgaccaggc
    11101 catagacaca gccgatcgcg actccgctgg cgaggacctg gacaaaggcg agcatggggg
    11161 cgaagcatag ccgaagcgcc gcccccgatc gcaccccgcg aaccgcggcg cccccctcca
    11221 cacccgccgc gacgccgcat gcaggggcgc cgccgcgatg gtccgcacca cacagcgacg
    11281 ggcgcacgac gctgcatgtc ccgcgaggcc ggacgcacga cggttcatgc tgcacggcga
    11341 cgcgcgcgac gcttcatgtc ccatgggcct ggacgcacgt agatccatat tgcacggcga
    11401 cggacgcgcg atggctcatg tcccatgggc ccggacgcac gtccgtccat gttgcacggc
    11461 gacaggcgcg ggatggttca tgtaggagcg ccggcaggcg cgaaatcggc ggtcagggag
    11521 gcgacgcgag ggggcgacct tcatcgccgt tttcgcgcct gccggcgctc ctagaggagg
    11581 cggcacgctt gtgcgccacg aaaagggccg gccggcggtg cggggtacac gcccccgcac
    11641 cgccggccgg ccccggaggc gactgccggg ctggagcgcc cccgatcagc cgaggaagcg
    11701 gtccaggtag ccctgctgcc aggccacgac caccgccgcg atcagcagca cgaggaagag
    11761 ccagctcttc cacggcgtct tcttctcggc atacgggtcg gtgagcgcgc gcgaggcgcc
    11821 cggaggcagt gccgcgacgc cggtgagcgc accaccgaag gggatgttga tgcgcgcgcg
    11881 cgtgttgacc gcccagccgt tggcgtcgag cagcgggccg aggttgcgct ggcgcagctt
    11941 gagccaggcc agcagcatcg acggaccgga gatcaccagc agcgcgccca ggaccaccag
    12001 cggcatctgc cacaccggca ggccgaggaa ggccgacacc accgcggcca gcgcggtgcc
    12061 gatcgcgccg agggcgagac ccatggcggc gaagataccg gcgaacttgg cgatgtcgaa
    12121 cggggccggc gcggcggcgg gcgcagcggc ggcggccggg gcggcctcga tcttggcgct
    12181 ggcgccggcg acgccggtcg cggcctggtc gttgaccgcc ttgtcgcgcg cggcggcgaa
    12241 cttctgcagc tgctcgccga tcatgcggcc gatgcgcttg tacggcgacc agaaggcctg
    12301 gcgcacgctg atcggcgcct ccaccacctt gaccacgctg gcgcgccagt cacggccctg
    12361 gcggtcgtag aagatgccgt tgcggccagg gaccatcatc tcgtcggcgt cgccgccggt
    12421 catcgcggcg acgatgttca tcggcgcctc gccctggcgc tggcactcgc agtacaccag
    12481 gtaggtgccc gacagcggcg cgagcgtggc gtggcgggcc atgtcgccca cgcgcaggca
    12541 gagctcgcag ctgcgctggt cgaggtagag cgtgccggcc tggaagatcg ccttgtcgtg
    12601 gcgcgagtag aagtcgctca gggtgacgaa gttgcgcagc aggcggacga ggtcgcggtt
    12661 gtagcgcacc aggcgctcga gcgcgtcgac ctggccggcc gcggtctcgg cggcgaggtc
    12721 ctcgtcgatc aggcgggtga gcgcggcgca ggtgccgtcg gcgagcagcg cgcgcacgtc
    12781 ggcgaccggc agcaccgcca ccgggttggc cggcatcgcc gccacccagg cgcggtgggc
    12841 ggcgaagcgc ccggccaggt cctcccattc ggcctgcgtc agcgcctcgc gcgcgcccag
    12901 gatggggatg acgacctggt cgcgcagcgc ggcgatgcgc gcctcccagg ccgggttgag
    12961 cccgaccgcc agcggcagcg cgcgacccgc gccgacgagc gcgagcggca gcgcggcgac
    13021 cgcggcggag gcggcgtcga gcgactgcag cgagagctcg gcataggcgg tgtcggcggg
    13081 gttgagcgcg gcggcggcgc gctcgtcgaa ggcggcgagg cggcagcggg tgaagtagtc
    13141 ctcgaccttc tcgcgcacgg cctcgaacac cgcagcggcg gcgccggtgg cgtcgcccag
    13201 cggcagcacg gtggcggcgt cggcctcggc ctgggcgtgc cagtcggaca cctcctgcgc
    13261 cgcggcgaag aaggcatcca cgcgcgcctg gtcgacaccc ggcttgccgc tgcggtcctc
    13321 ggcggcgccg taggtgtcga cgatgcgggt gatcgccccg gccaggcgcg ggtcgccggc
    13381 gagctcggcg ggcaccacgc cgtcaccgtt ctggtgctcg ggcgcgaaca gcttctcggt
    13441 ctccgcaagg tcgcccatgg agatctctac cgcgtcggcc ttgccgacgt aggccagcac
    13501 cttggcggcg gtggcgagca agcgcgcgcc ctcggcgttg gtctcgtcga tcgccgccag
    13561 cggcaggccg tcggcgccgc ggaacagcac gtccgggtcc ttcagcaccg tacacaccca
    13621 gcgcgtggcg tcgatgatct cgggcgcgcg gatgctgccg tcgtcgtcga cgtcgagcag
    13681 ctgcagcgtg cgcgtgtcga actccaggcc ggaggtcgga caggccagca ccgaccacag
    13741 cttctggtcg agctcgccaa ggtggcgcag gtcgtcggcg gtctcgatgc ggacctggtc
    13801 gaagcccccc gagcggaaga accgccactg atagcctttc ttcttgcttt cgtcgctcat
    13861 gttctcgaac actccctgtc gttatgcggg cagcacccgc aagccatgct caagggaaga
    13921 tgttgcgccc gaaaaccggg ccgaacaagc gatggacttc ccgaatccgg cacctgccgg
    13981 agggatcccg ggaaatcgaa tggcaagacg ccaaaaacgc ccgaaacaga gcggcgcagg
    14041 ctccaccgct cagccgtagg cacccacgaa ggggttgctg tcgcgctcct cgccgaaggt
    14101 cgaggtggga ccgtggccag ggatgaaggt gatgtcgtcg ccgagcggga agagcttctc
    14161 gcggatcgag cggatcaggg tctggtggtc gccgcgcggg aaatcggtgc ggccgatcga
    14221 gccggcgaag agcacgtcgc cgacgatcgc caggcgcgcg ccctcatgta cgaagacgac
    14281 gtggccgggg gtatgcccgg gcgtgtggat gaccttcagc gtctgctccc cgacggtgac
    14341 ggtgtcgccg tcgtgcagcc agcggtcggg ctcgaaggac tcgacgtcgg ggaagccgaa
    14401 catcttgctc tgctgcggca tgccctcgat ccagaagcgg tcctcctcct gcggcccctc
    14461 gatcggcacg ccgagctcgc gcgccagctt cgcggtgccg ccggcgtggt cgatgtggcc
    14521 gtgggtgatg aggatcttct cgaccgtgac gccgagctcg gcgaccgtgg cgaggatgcg
    14581 atcgaggtcg ccgccggggt cgaccaccgc ggccttcttc gtgcgctcgc accacaggat
    14641 gctgcagttc tgctggaaag gggtgaccgg gacgatggtg gcctggatca tcggaagcgc
    14701 tcctgaggat gtggattcgg cccggagttt agccgatgag gcgccgcgtc cgcggcgtga
    14761 acgggaagcg ggcctgcccg cgcagcggct tcctcgagga agccgcttgc cggcaggccc
    14821 gccccttgcg cgacgtcagc gttcgatcag atcacgccct gcgccagcat ggcctcggcg
    14881 accttgacga agccggcgac gttggcgccg tcgacgtagc tcaccgtacc gtcctcgcgc
    14941 tcgccgtact tcaggcaggc ggcgtggatg ccgagcatga tctccttgag gcgggcgtcg
    15001 acctcctcgc gggtccacga caggcgcatc gcgttctggc tcatctccag gcccgaggtg
    15061 gccacgccgc cggcgttgga ggccttgccc ggcgcgtaca gcacgccgtt gtgctcgaag
    15121 atcttcaccg cttccatggt gctgggcatg ttggcgccct cggcgaccgc gaccacgccg
    15181 ttcttgacca gggtggcggc gtcgttgccg tcgagctcgt tctgggtcgc gcacggcagc
    15241 gcaacctgca ccggcacgtg ccacggacgc acgcccggct cgaagcgggc gccgacgcgc
    15301 tcggcgtact cggccacgcg gccgtagtag tggttcttga tctccatgag gatcgccagc
    15361 ttctcggggg tgaagccggc ctcgtcgatc acggtgccgc tcgagtcgga gcaggtgatc
    15421 ggcttggcgc cgagctccat cagcttctcg atggcgtact gggcgacgtt gcccgaaccc
    15481 gaaaccgaga cgcgcatgcc cttgatgtcg cggccggcgc gctcgagcat ggcgttggcg
    15541 aagtacacgg tgccgtagcc ggtcgactcg ggacggatca gcgagccgcc gaaggacagg
    15601 cccttgccgg tgaacacgca ggccgagttg ttcgacagct tcttcatcat gccggccatg
    15661 aaaccgacct cgcggccgcc cacgccgatg tcgccggcgg gcacgtcggt gtcgggaccg
    15721 acgtggcggt acaactcgct gatgaaggcc tggcagaagc gcatgacctc acccgggctg
    15781 cggcccttgg gatcgaagtc ggaaccgccc ttgccgccgc ccatgggcag cgtggtgagc
    15841 gcgttcttga aggtctgctc gaaggcgagg aacttcagga tcgacaggtt caccgagggg
    15901 tggaagcgca ggccgccctt gtaggggccg atgccggagc tgtgctggat gcggtagccg
    15961 cggttgacct ggacctcgcc acggtcgtcc acccacgaga cgcggaacat gatcacgcgc
    16021 tcgggttcga tcagccggtc gaggagggag tgctccgcat agcgcttgtt ggccgagatg
    16081 aagggccaca ggctctccat gacctcggtc acggcctgca gaaactcggg ctggccgggg
    16141 ttgcgctgtt cgacgtaggc caggaactcc tcgagggact gatatttcat gatgttggac
    16201 ccatggattg attgaagaca ggtttttttt gcgcgcgcgc acacgcgatg gcctcggttt
    16261 tacccgaggc catcgcgcaa tgcagcgcca gcattgtgca tcaactcccc tcttttggtg
    16321 catgatcttc gtcaaacttg ctgcatttat gacatccagc tccttcatgc accgttctcg
    16381 tgcatggcag catgccctcc gacccggcgt tcaaccgcag tgcatggacc cggaatgacc
    16441 taggggttat gctggccgtg cacgtgtagc caaaccaacg acagggaggt gttcatgggt
    16501 ctgttcgcat tcatcaagga agcaggcgag aagctcttcg ggacgggcga ggccaacgcc
    16561 gccgccgatc cggccgcggc caacgccaag gcggcgcaag ccatccacga ctacatcgtc
    16621 gcgctcaaga tcgcgccgcc ggatctgggc gtgagcttcg acgccgccaa gagcctggtc
    16681 accgtcagcg gcaccgcgcc cgaccaggcg acgcgcgaga agatcctgct cgccgccggc
    16741 aacgtcgccg gggtggccga ggtcgagaac cgcctgagcg tgtcccgtgc cgaacccgag
    16801 gcgcagttcc acaccgtggc gcgcggcgac acgctgtcgg cgatcgccaa gaagtattac
    16861 ggcaacgcca accagtaccc cgcgatcttc gaggccaaca agccgatgct gagccacccg
    16921 gacaagatct acccgggcca ggtgctgcgc attccgccgc aggcctgatc acgcagcacc
    16981 ggcaggcggc tttccgcttg ccccgccgag gcccgggccg ttacgctcgg gcctcttcct
    17041 tttccgcctc cgcaaacccc cgccatggcc cgcatccgga tcgagctgcc cgaccgcttc
    17101 gccttctcca ccgacatccc gctgctgatg tcgcacatca actacggcaa ccacctcgac
    17161 aatgcccagc tgctcggcat cgtctccgag gcgcgcgtgc gctttctcaa gtccatgggc
    17221 tattcggaac tcgacatcga gggcctcggc atcatcgtcg ccgacgccgc gctgcaatac
    17281 cgctccgagg ccttccacgg cgagaccatg cgggtcgaga tgggcgtggc cgacttccac
    17341 gagcacggct gcgacctggt gtggcgcatg gccgaagccg cgagcgggcg cgaggtcgca
    17401 cgcggcaaga ccggcatcgt cttcttcgac tacggcgaac gccgcaaggt cgcggtgccc
    17461 gagggtttcc gccgtcgctt cgcggcggcc taggcacacg tgcagcacgc acgcgtcgca
    17521 gtggtcggtg gcggccccgc cggcctgatg gcggcgggcg cgctcgccga gcgcggctgc
    17581 acggtgacgg tgtacgacgc catgccctcg gtcgggcgca agttcctgct cgccgggcgc
    17641 ggcgggctca accttaccca ctccgaaccc ctggccgact tcctcggccg ctacggcgac
    17701 cgccgcgacc cgctcgcgcc gctggtcgag gcctttccgc cgcaggcgct gcgcgagtgg
    17761 gcgcacggcc tgggcgtgga gaccttcgtc ggcagctcgg gccgtgtctt cccgaacgaa
    17821 atgaaggccg caccgctgct gcgcgcctgg ctcgcccgcc tgcgcgcggc cggggtgcgc
    17881 ttcgcggtgc gccatcgctg gctgggctgg gcgggcgaag cggcacaggg tggcccggtg
    17941 gaggaccacc ctgcgccgga cgccgcgaac gcggacgaac gccagccccg cccgcagcgc
    18001 ctgcgcttcg ccacccggga gggcgaacag cacgtcgagg ccgacgcgct cgtgctcgcg
    18061 ctcggcggcg gcagctgggc gaagctcggc tctgacggcg cctgggtggc cccgctgcgc
    18121 gccgcagggg tcgaggtcgc cgacctgctc cccgccaact gcggcttcga cgtcgccggc
    18181 cccgccggca ccggctggag cgcgcacttc ctcgaacgct tccgcggcca gccgctcaag
    18241 tccgtcgccg cgcgctgcac cgaccccacc ggccgcatcc acgcgcgcgc cggcgaatgc
    18301 ctgatctccg ccaccggcat cgagggcggt ctggtctatg cgctctccgc cccactccgc
    18361 gacaccctgc tcgcccgcgg cgaggccatc ctcgaactcg acctcgcccc cggccgcagc
    18421 ctcgagcgcc tcgccgccga gctcgcccgc ccgcgcggca gccgctcctt cgccagccac
    18481 ctgcacagtc aggccggcat caagggcgtc aaggccgggc tattgcgcga atgcgtggac
    18541 aaggccgggc tcgacgaccc cgcccgcctc gccgcggcca tcaaggccct gccgttgcgc
    18601 ctcctcgcca cgcgcccgct cgacgaggcc atcagcagcg ccggcggcgt acgcttcgaa
    18661 gcgctcgacg cccacctgat gctgcgcgcc cgccccggcg tcttcgtcgc cggcgagatg
    18721 ctcgactggg aagcccccac cggcggctac ctgctgaccg cctgcttcgc caccggcctc
    18781 gctgccggaa ccgccgccgc cgactggctg tcccatcgcc cctgacgctc cactcctctc
    18841 ccccgacgcc tccccctcac ccctcacccc ccaatgaacc tccatccctt cctggtcgcg
    18901 atcgaagtcg gcggcaccct ggccttcgcg atgtccggtc tcatcgaggc cacccgcaag
    18961 cgcatggaca tcgtcggcgt gttctcggtc gccttcgtca gcgccttcgg cggcggcacc
    19021 ctgcgcgaca tcctgctcga ccgccgcccg ctgttctgga tcgagaacca ggaatacctc
    19081 tggctcgtgc tggccatggt ggcgaccacg ccgctgtggc tgcagaccct gcgccacaag
    19141 gtcggcggcc gcctgatgga gctcgccgac gcgttcggcc tcggcctctt cgccatctcc
    19201 ggcgccacgc tggccgacgc tgccggcatg ccggcgctgg tgtcgatgat gatgggcgtg
    19261 gtcaccgcgg tgttcggcgg cgtgtcgcgc gacgtgctgt gcaacgaggt gcccaaggtc
    19321 tatagcgacc accgccccta cgcgatgtgc gcgctgttcg gctgcggcgt cttcctcgcc
    19381 ctcaacgcga ccggcctgcc gctgccgatc accaccctgg ccggcatcgc caccgccacc
    19441 ggctcgcgcc tactcgccct cgtcttcgac gtgcgcctgc cggcgtggcc ggcgcaccgc
    19501 gactgaacgg ggcgcgctgg ccgacgccac ctaccagttc gactcgcgct cggccgtcgc
    19561 cgtgatgcgg tggatcgaca ggtcggcgcc gttgaactcc tcctcctgat cgagccgcag
    19621 ccccaccgcg agcttgagcg cgccatacac cgccgccccg ccggcgagcg ccacgccgat
    19681 gccgagcgcc gtcatcaccg cctgcgaggc gagcgccacc ccgcccaggc cgcccagcgc
    19741 ctcgctgccg aagatgcccg ccgccagccc gccccaggcg ccacacagcc cgtgcagcgg
    19801 ccacaccccg agcacgtcgt cgatcttcca gcggttctgc gtcagcgtga acatcaccac
    19861 gaacagcacc cccgccaccc cgccgaccac cagcgcaccg agcgggtgca tcacgtccga
    19921 gcccgcgcac accgccacca gcccggcgag cggcccgtta tgcacgaagc ccgggtcgtt
    19981 gcgcccggcc gcgagcgccg ccaccgtgcc gcccaccatc gccatcagcg agttgatcgc
    20041 caccagcccc gagatgttct ccaggcgctg cgccgacatc acgttgaagc cgaaccagcc
    20101 cacgatcagg atccacgcgc cgagcgcgag gaagggaatc gacgacggcg gatgcgccga
    20161 gatctggccg ttgcgcgcat agcgtccgcg ccgcgccccc agcagcagca ccgccggcag
    20221 cgcgatccag ccacccatcg catgcaccac caccgagccg gcgaagtcgt ggaactccgc
    20281 cccgaagctc gccttcagcc aggcctggac gccgaaggcc tggttccacg cgatgccctc
    20341 gaagaaggga tagacgaaac ccaccagcag aaaggtcgcc gccagctgcg gctggaagcg
    20401 cgcgcgctcg gcgatgccgc ccgagatgat cgcggggatc gccgcggcga aggtcaacag
    20461 gaagaagaag cgcgtgagct cgaagccgtg gtgttccacc agcgcgccgg cgccggagaa
    20521 gaaatgcacc ccgtaggcga tgccatagcc gatgaagaaa taggccagcg tcgacaccgc
    20581 gaagtcggac aggatcttga ccagcgcgtt gacctggttc ttccgccgca ccgtccccac
    20641 ctcgaggaag gcgaagccgg catgcatggc gaggaccatg atggcgccca gcaggatgaa
    20701 cagcacgtcg ttgctcgttt gaacgggttg catgatgcct ccgaaagtga cgggcatcct
    20761 tagcaagcac cgttccagtg cgatgaaccg ggtgaaatcc gatggatcac gccatgatgg
    20821 tgcggaggga gcgcaccagc gaggtgcgtg ggcggagggg gacgcacctt ggcggggcgc
    20881 tactacggct cctgcagggt catgggcgcg ggctgttctt ccgtagattc cggcaagcag
    20941 accgcggtaa ccggcccgtg aacggccggg tggtttcgtc aggctagggt gtccgggtcc
    21001 tgcatccagg cgggaatgtc gcgctggccg tgcagtacgc gccagacatc gatgtggtcc
    21061 gggcgctcga tgtagaacac gaggtagggg taagacgaca gcgcccaggc gcgtagcccc
    21121 ggaaggtcca gctcgtgccc atggcgaggc gaaccggtgc cggggtggcg cccgatgtgg
    21181 gtgtagcccc gttccagtgc gtcgatgaag ccgagcgcga ccgacgagga ggcctcttcg
    21241 aggtagtggg cgatcgcgtc gtcgacgtcc tggttggcct gctcacgcgg aatgactggt
    21301 ttgatcttca cccgcgggaa tcgggctcgg cagcccggcg cacccggtca cgcagacctt
    21361 cgaagtaagc ggcatccgcc ggcgacgcag gcgccgtggc cgcgccggcc agcagcacac
    21421 cccgcaagcg ctgtcgatcc tgatccttgc ggatcaattc gcgcacgtac tcgctgctgg
    21481 tgccgtagcc gcgttcgctc acctgctggt ccacgaagga tttcaggctg ttgggcaggg
    21541 aaatgttcat cgtgctcatg cgctcaggct agccggcttg gcaaaatttg gcaaggcagc
    21601 ggagttccct ccatcgtgcc agtcatgccg ggcgaccgca tccctgcagc gccgatggcc
    21661 gcagcgggca ggctcgaggt tgtcgccgac cggacgcaga gccgctggga gtggcgcggg
    21721 tggcgggcgt cacggtccgg ccatttgctg ccacacatgg tagtagcaga atcgtcattc
    21781 cagcgaccgg tgagctccgg aaccagccat agagcgagct gaggccaacg tggctcgtaa
    21841 gttggccggc actgcgctct tgaagccgat gctcaccagc tctgccgtca gtgtcgggca
    21901 aaaaccgccg cgcttccgtc aagcccgacc aggagtgtct catagggttg cggggtcgac
    21961 gtctccatcc ccggcgaccc ctgcggcatg cccggcgtag ccagtccgat ggcctttggg
    22021 gactcggaga gaagccgtcg gatgtcgtcc gcagggacgt gcccctcgac ggagtaggaa
    22081 ccgaccttgg ccgtgtgaca cgagccgtat tggtccggca tgcccagtgc ctcgcgggct
    22141 gcggggacat tgtcgacgtc tttcgtcacg acatcgaagc cgttctttct caggtgctcg
    22201 acccatttcc cgcagcaccc gcagtaagcg ctcttgtaga cctctacacg tacgggcccc
    22261 tgcgcaaacc ctgcgccgct catgatcatc aggcttgcta agagtccacc gagcaaagtc
    22321 ttcgtcttca tgttcgtctt ccggttgatg gcgtcgaggc atagtttggc gtttcgagcc
    22381 caacgggaag ctgacctcaa aattacattt ccgtcagaca gccgggactc cggtcgactt
    22441 tgcagcatca ggaaggcgat gaggcttcat tgcgaggcaa ggtgatcgtg aagcaggtga
    22501 caccttcagc ggagcgcgca gtgatgtgac ccccgtgggc ctgcacgatg gaacgcgtga
    22561 tcgcaagtcc gagccctgcg ccttcaccgc gagactcgcg ctgggcgcta ccgcgatgga
    22621 agcgttcgaa aatccgttcg atctgatcgg cgggtatcgg gtcgccgaca ttgcaaacgg
    22681 cgagacggac gccggctgcg tccgcgtcga ccctgatcgt gatctgtcca tttttcggtg
    22741 tgtgacgaag cgcattcgaa atcaggttcg acaaggcgcg ccgcagcatc aggcgatcac
    22801 cctgaacgct cgcttggcct tggcgcacga tgcggacttg gccctcttcg gccaaggctt
    22861 cgtagaaatc gatcagcgca tccgcctcgc gggccaggtc gatcgcctcg cccgcgtgcg
    22921 cgagggtgtt ctcctcggcc ttggcgagga acagcatgtc gctgaccatg cgtgcgatgc
    22981 gctcgtattc ctcgaggttc gacgccagaa tgtcctgata ttcgtcgagc gtgcgtggcc
    23041 gcgacagcgc gacctgggtc tgggtcatca ggttcgagat cggcgtacgc agttcgtggg
    23101 caatgtccgc cgaatagtca ccgaggcgct ggaaagcggc ttcgagccga gcgagcatgc
    23161 cattgaaggc ttcgacgtgg tcgcgcactt ccagcggcgc atcatcgatg gcgagacgct
    23221 cgccgagttg ccgtgccgac agcctacggg cggtttcggt gacccggcgc agaggggcga
    23281 ggccccggtg cgccgcaaac cagcccaata gcgccgccgc caatgccgcc acgacgacgc
    23341 ccgcccaggt ggcgttgtgc accgacgcga ggaaatggac gtgatgcgac agatcgagtg
    23401 cgaccagcgc ctcgatcgtt tgctccttcg acccaaggct cggtagcgtg attctggcct
    23461 caagccctcg atgggggcgc tcgtcgaccg tccagtcagc cagcccaccc gaaatgcgct
    23521 cgcctgcccg ctgagcagcg gtgaaatgct cgggatggat gatgtacagg acgcgcccct
    23581 cgacgtcgcg tagcaggaca cccacgctct cgtgtccaac gaaggaacgt tcgagcgcct
    23641 caacgcgttc cggtcggccc ccagtcgcag caacatcttg cagcgtgttg cggatgagcg
    23701 agacctttcc ctgcaactcg tgcatgtcca gttcctggaa atgcgcgtcc aacatgcgcc
    23761 caaagagtac cgccaccagc acgagcaggc ccgcagcgag gacggcaaat agtgttgcca
    23821 gtcgcgccgt tagcgagtga atgcggatca tcgtcagctc ggctccatcg cttcgagcac
    23881 gtagcccatg ccgcgcacgg tgcggatcag cttgggctcg aaggggtcgt cgactttcac
    23941 ccgtagcctg cgcactgcga cctcgatcac gttggtgtca ctgtcgaagt tcatatccca
    24001 cacctgcgaa gcgatcaggg agcgcggcaa cacttcacct ttgcggcgca gcagcagttc
    24061 cagcagggca aactccttgg cggtcagatc gatacgctgc ccgcatcgcg tcaccctgcg
    24121 gcgaagcaga tcgagttcca ggtttgccga gcgcaggatc tccggttcat gaccccgtcc
    24181 cctgcgcagc agggtgcgga cccgcgcgag gaattccgag aacgcgaagg gcttgatcag
    24241 gtaatcatcg gcgccgagtt cgaggccacg aacccgatcc tcaacttggt cacgggcagt
    24301 caggaacagc acgggcgtct cacgaccgcc gcgccgaagc gtctgcaaga tgccccagcc
    24361 gtcgagcgac ggcagcatca catccagcac gatgaggtcg tagtcgccag caagcgcgag
    24421 gtgaagccca tcgaggccat ctcttgcgag gtcgactacg aacccggcct cggtcagccc
    24481 ctggcgcaga tagtcgccgg tcttcacttc gtcttcgacg atcagaattt tcattttttc
    24541 gctcctacgc gcttcgtgct gcctgtggcc gattttgccc ccggggtgct ggataacacc
    24601 cgggcttaca gaaatgtaat ttccgggtca ggccgacgac aggcaggcgg gcgcaagatg
    24661 ctctgcgtgg cacagcgttc cgtaccgcga cggaaccccg caaccaatgg gagatcgatc
    24721 atgaaactgc gtttgtaccg tctcgccggg ctcatgcccg tcgtcgctct ggccgcagcc
    24781 ctgcacggta gtccggtcgt cgcgcagacg accgatccgg cgcaggcctg gccgcccgca
    24841 gcgagtgtcc ccgcgcttca ggaacgtatg aagtcgatcc gtgccgagac cgacccggaa
    24901 cgtcgcatgg ccctgatgga agagcagatc aaggccctgg aggctgcatc gcagggcacg
    24961 cccgctggtt gcccgatgat gggggggcag atgggggctg gtccgatgat gaaggggggt
    25021 ggtcctggac ccggggctgg acccatgggc ggcatgatga tggatcccaa gctcatgcag
    25081 gagcacatga agatgatgca agagcacatg ggcatgatgc agaacatgat gaagatgcat
    25141 ccggccgcca agccggcgat gcccaactga gcatcgggac gcggagcggc gacctcgtcg
    25201 atcgccccgc gtccgattca tcacaagacc aacaaagaga cattccccat gcagagacga
    25261 ctcatccacc tcggtggagg attggccgtc gccgtggcgc tcgtgtcggg cgcgcaggcc
    25321 gagccctcct ctccgtctaa tcccgctgac cacgcgcctg ccgcgaccca gtctgggtca
    25381 cccaagccac agcgcgtgcc ggcgtatcgc tcgcccctga acgaatatcg gccctaccgt
    25441 gtcgatgagc ccttgcggtc gtggaaggat gccaacgacg aggctggacg tctcggcggg
    25501 cacatgggcc acctcacgcc gacttcgaaa gggggcgagc gatgagagcc agtctcccca
    25561 tatccttgct ggccgccacc gtgctgaccg ggtgcgccag cgttgcgatc gatgagaact
    25621 tcgctgaggt cgagcgcttt gcgcgcgagc agacgggtag cgaggtgcgc tggctgcgct
    25681 cggaccctga gcgcgaggcg atgcgcgccg aggtcgatcg cctgctcgca cagccgctgg
    25741 cgatcgacga cgcggtgcgc atcgcgctgg gctacagccc ggcgttccag tccctgctgg
    25801 cggaagccgc cgtggcctcg gcggatgcga ccggttcggc ccgcatcggc aatccggtgt
    25861 tcaccttcga gcggttgttt cgctcgggcg ccgaggggcg cgaactcgac atcggccgtt
    25921 cgctcggcat ctcgctgttc gacctgctgt ttctgcccgc gcggctggag caggccgagt
    25981 tccgccagca gcagacccgg ctgcagtcct cgattgcgct gttgagcacc gtcactgaag
    26041 tgcgccaggc ctgggtcgat gcggtcgcgg cgcgacaggt cgcgcgctac cgcgaggagg
    26101 tggccacggc cgccgggacc gctgccgagc tcgcccgtcg gatgcaggcc accggcaact
    26161 tcagccgcct gcagcgcgcg cgcgaacagg cgctcgccgc cgaggaaacg gccaacctga
    26221 tccgcgcccg ccagaacgcc accgccgcac gcgaaaccct gatccagcgt ctgggcctca
    26281 ctccgagcca ggcgcaggcg ctgcgtctgc ccgatcagtt gccggccttg cccgaggcgc
    26341 cgatggacga agccaccgcc ggtgcggcgt tgctggagaa ccggctcgac gtgcgcatcg
    26401 cccgcaccga tctcgaccgg acggcgaaga gcctgggcct cacgcaggtg accagcgtgg
    26461 tcaacggcct gcatgtggcc ggcgtgcgca acagcgagac cggcgagtcg tcgcagcgcg
    26521 gcttcgaagt cgaactgccg ctgcccctgt tcgacttcgg cgatgcggcc cgcgccagca
    26581 gtgaggcccg ctatctctcg gccttcaacc gcaccctcga ggttgccaat aacgccagct
    26641 cccaggtccg cgtggcctac gagggctacc gcagtgcata cgacctcgcg cgccactacc
    26701 gcagcgaggt ggttccactg cgtcagaaca ttaccgaaga gtcggtgctc cagtacaacg
    26761 ggatgctgat cggtgtgttc gagctgcttg ccgctgcccg cgctcagtcg gccagcgtgg
    26821 tgcaggcgat cgaagccgaa cgcgacttct ggcgcgccga ggccgcgctc aaggccagcc
    26881 tgctcggcca gccgatcgca ccgatcagcc ttcaatcaag cgcatcgccg gcagaagccg
    26941 gcgctggcca ctgacctgtc cggagacgat catgaccacc cgacgcagct ttctcgccgg
    27001 ggcaggcctg ctggccgctg ccggaaccgt caaccgagcc gcgctcgctg cgctgcccga
    27061 gcccgtaatt cagaccagcg cagccacggc ggccccgctg accccgccca caggccgccc
    27121 gtacgacccg gtcgtcacgc tcaacggctg gacggcgccc tggcgcatga acgctggggt
    27181 gaaggagttc cacctcgtcg ccgaacccgt cgagcgcgag atcgcccccg gcatggtggc
    27241 gcggctctgg ggctataacg gccagtcgcc cgggccgacg atcgaggtcg tcgagggcga
    27301 ccgcgtgcgc atcttcgtca ccaaccgcct gcccgagcac accaccatcc actggcacgg
    27361 ccagcgcctg cccaacggca tggacggggt cggcggcctc aaccagccgc agatcccgcc
    27421 gggcaagacc ttcgtctatg agttcgtcgc ccgccgcccc ggcaccttca tgtaccaccc
    27481 gcacgccgac gagatggtgc agatggcgat gggcatgatg ggcatgtggg tcacgcatcc
    27541 gcgcgcgccg cacccgcaca tcgcgggcgt ggaccgcgac ttctgcttcc tgctcaacgc
    27601 ctacgacatc gagcccggca gctacgtgcc caagatcaac acgatgctcg acttcaacct
    27661 gtggacctgg aacagccgcg cctttccggg catcgactcg ctcaatgtca ggaagggcga
    27721 ccgcgtgcgg gtgcgcatcg gcaacctgac catgaccaac cacccgatcc acatccacgg
    27781 ccacgaattc caggtgaccg gcaccgacgg cggcccgacg cgccccgagt cgcgctggcc
    27841 cgaggtcacc accgacgtgg ccgtcggtca gatgcgccag atcgagttca tcgccgacga
    27901 ggagggcgac tgggcgatgc actgccacaa gtcgcaccac accatgaacg cgatgggcca
    27961 cgacgtgccg accatgatcg gcgtcgatca tcgcggtctg gtcgaagaca tccagaagct
    28021 ggtgcccgac tacatgctga tgggcgagcg cggcatggcc gacatgggcg agatggagat
    28081 gcccctgccc gacaacacct tgccgatgat gaccgggcag gggccgttcg gcgcggtcga
    28141 gatgggtggc atgttcaccg tgctcaaggt gcgccgtgac cagaaaccgg gcgactaccg
    28201 cgacccgggc tggttcaggc atcccaaggg gacggtggcc tacgagtggg cgggcgcagc
    28261 gctgcctgaa cccgctcgcg gcgacgcggc gggcgcctcg agcatgccgc gtacagcggg
    28321 cggaccgcct gtcgagatgg ccgtacgcaa acccactggc catcaaggtc attgaggtcg
    28381 aacgccgtgc aatcggcgca aaccccggca caaatgaagc ctcacccaac agagagatgg
    28441 agatccccat gaaaagtcgt cgtcgatttc tggccaccag ccttgccgcc ggtgtgcttg
    28501 ccgttcaccg cagcacgttc gcccatggca atgccgaaca tgccgacaac gcagcgtccg
    28561 atacccccaa ggagcagcag caatggggga ttgcggggga cgcgaaagcc gtctcgcgcg
    28621 cgatcgccat cgtgatgacc gatgagatgc gcttcgttcc ggaccgcatc gaggtgcgtc
    28681 tgggcgagac gatccgattc acccacgaaa atcgaggcgc ggtgatgcac gagatggtgg
    28741 tcggtacgcc caagacgctt gccgagcacg cggagatgat gcagcgcttc ccggagatgg
    28801 aacatgacga accgtggatg tcgcatgtcg cgccaggtgg gcgcggagaa atgatctggc
    28861 acttcaaccg tgcgggggac ttccagttcg cctgcctgat tcccggccac ttccaggccg
    28921 gcatgatcgg cacgatcaag gtcggctgac agaaatgtaa tccgtgcgtc agcgtcccgt
    28981 tggtgagcgc ttcgcataat cgtgctcact ctcgaactca cacagaattt gaacccttgg
    29041 agaagcccat catgaaaaag accctcatca ccactgcgct cctggccttg ctcggcggcg
    29101 gcgccccgct tgcgttcgca caggccgatc acgatgcaca tcacggcggg gcgagtgccc
    29161 cggccgacgc caacgccaag ctggccgagg gcacggtcaa gaagatcgac aagtcggctg
    29221 gcaagctgac cattgcccat ggccccctgg agtcgctcgg catgccggcg atgaccatgg
    29281 tgttccgcgc ggccgagccg ggcatgcttg atcaggtcaa ggcgggcgac aagatccggt
    29341 tcgcggtcga gaaggtcggc ggtgcgctga ccgtgacgtc tctcgagccc gcccagtgac
    29401 gcctatcccg caggtgcgtc gcgttccact ctgaccggcc agccgtgggg atgccccact
    29461 gagtggctga acgacgaggc gggtggcgaa gggcctgcgc atgcacttga ccgcctgccg
    29521 gaatcgtttc tcgatgaaat ccccgttcgc agtaccctca tctcacctgc tacgtcctgc
    29581 agcgcttgca ctggtggtcg cgctcacgct gggaagtggc agtgcctgga cacagggttc
    29641 gcccgacact ccaacgctcg gctcgagccc ccaggcgctg attgaatatg cgcgccacag
    29701 caaccccggc tttgccgctg cccgcgcgga agcgtccgca gcgcaggagc gcgtgacgcc
    29761 cgccggtgcg ctgcccgacc cgacgttcga ggtcgagctg atggacgcca ccaacaccat
    29821 gagcgggcgc tcggcgtcgt tgctgcccgg ccaggtgggc gagacccgct accgcatcac
    29881 ccagccgcta cccgggtggg gtaagcgcga gctggcggtg aaggccgccg aagcccaggc
    29941 gacccaggct gatgcgatgc gcgatacctc ctgggctgag ctcgcggcaa agatcgagac
    30001 gctgtggttg cgctactacg ccgccgaccg cgaactcgtc ctcaaccgcg agggcttgac
    30061 cctgctgcaa agcctggagg cgctgagcct tacccgttac gagctgggtc tgctgccgca
    30121 gcaggcggtg ctgcgcatgc agcgcgaaat cactgcccag cgcctcgcgc tcgtggaggt
    30181 cgaacagcgg cgcaaggggc tggcagcggg gctcaacggc ctgctcggcc gggcgcatga
    30241 tgcgccgctc gccacacccg cagatccagc ccccttgccc gagcagctgg aggcgggcgc
    30301 cctttttgag tcggcggcca gtgccaaccc ggacgtgaat gccgccgcct acggcatcga
    30361 cgtggcacgt gccgagcgcg aacgaacgta tcaggaccgc ttgccggact tcgccgttgg
    30421 cgtgcgcaac aaccgtcctg atgaaggtaa gtcgtcctgg gacgtgatgt tcgaggtgat
    30481 gatcccgctg caacagtcca gccgtcgcgc caaggagcgc gaagccgaat acatgctgat
    30541 ggcggccgag gcgcggcggg aggatgccaa ggcgcgcgca tccggcgaac tgggtatcgc
    30601 ctggtcgatg tacgcgcagg gccgcgagac cttgcgcctg ctcgaacata cgctgctgcc
    30661 gcaggcccag gccacccggg atgcaagtca ggccgcgctc agcagcggca aggtcgactt
    30721 cgacagcgtg atcgaagccg agcgccagct catcgacatc cggactcaac gcttgaaggc
    30781 cgagctcgac acgcgcctgg cgctgacaga aatcaagaaa ctgacagggg atctgaagtg
    30841 agctcagccg ttcgaatgac ggcgatcgct gcgggcgtgg cgattgccat aggtgcgggg
    30901 tactggattg cgcacctgca aaatgctgga aatccagttc cgctgatcag cgaaagccag
    30961 gcgcaaagcg atagcgcagc cccggccgac ggcgaacgca agatcctcta ctaccgcaac
    31021 ccgatgggcc tgcccgacac ctcgcccgtg ccgaagaagg attcgatggg catggactac
    31081 atccccgtct atgccgacga ccagccggac gacagtggcg cagtggtggt cagccccgcg
    31141 cgcatccaga ccctgggggt gaagactgcc gaggttgaac tgcgcgccgt ggattcggcg
    31201 gtgcgcgcga gcggccgtat cgagttcgac gagcgcaggc aggtggtggt ggcaccgcgc
    31261 ttcgagggct ggatcgagcg cctgcatgtg aatgcggtcg gcgacccggt gaagaagggc
    31321 cagccactgt tcaccgccta cagcccggaa ctgcaatcca ccggcgagga actgcgcatt
    31381 gccgagcgcc tggccagcca gaacgcggcc catgatccgc tggcgagcga atcctcccgt
    31441 cggctggccg aggcgacccg tgcgcgcctg cgcaacctgc aggtggccgg ccaggccggc
    31501 gcgcgccagg tgttccacgc cccggcgagc ggcgtggtgc tggagaagga ggccatcgaa
    31561 ggcggacgct tcatgccggg cgaggcactg ttccgcatcg cagacctgtc gaaggtgtgg
    31621 atcatcgccg acgtcttcga gcaggatctc gcccgcgtgc aggtcggcca gagcgcgcag
    31681 gtgacgctcg aggcctatcc cggtcgcggc ttcgcggcgc gggtcgatta cctctatcca
    31741 accctcgacg ccgccacgcg cagcacccgc gtgcgtctgg aactggacaa tccggagggc
    31801 ctgttgcgcc caggcatgtt cgcccagatc gcgctggcgg caggtgatgc caccccgagg
    31861 gtcgccgtgc cgagctcggc gatcatcgac gatggcgaac ggcgggtcgt gctgattgcg
    31921 ctcggcgaag gccgcttcaa gccgcagcca gtgaagctcg gccagcgcgg ccgggatgtg
    31981 gtcgaggtgc tcgacggcgt gactgcgggt gatcgcgtgg tggtttcggc caacttcctg
    32041 atcgactcgg agagccagct caaggcggca ctctccaacc tggttgagcc cgatgcccgc
    32101 gatcaggctc aagcgagccc gacccgttac gaagcgcaag ggacgttcga tgcgctcgac
    32161 gccgaaggcg gcagcgtgac gatgacgcat ggcgagatcc cggccctcca gtggccggcg
    32221 atgaccatgg acttcaagct tgccgatccg gcgttggtga aggacatcgc cccaggctcg
    32281 gcggtgcgtt tcgtcttcga ggcgggtgag cccggggagt acatcatcac gggcatcgag
    32341 ccggctgcga gtagcgcggc ggctccagcc gccgccggcc atgcggggca ctgagatgga
    32401 cgcccctgtg atggaacctt caaacgctgt gcccaccgac acggcagcga ggccggctgc
    32461 gcccggcctg ctcgatcgcg tcatcgactg gtcggcgcac aacgtcttcc tggtgctgct
    32521 cgccacgctg ttcctgatcg gcggcggcgt gtatgcggtc aagcacaccc cgctcgacgc
    32581 gctgcccgac ctgtccgacg tgcaggtgat cgtctacacc gattaccccg gccaggcgcc
    32641 gcaggtggtc gaggatcagg tcacctatcc gctcaccacc tccatgctgg cggtgccgcg
    32701 cgcgaaggtg gtgcgcggct tctcgatgtt cggcgcgtcc tacgtgtatg tgatcttcga
    32761 ggacggcacc gacatctact gggcgcgctc gcgcgtgctc gagtacctga gttcggccgc
    32821 cggccgcctg ccgcagggcg tggcgccgca gatcgggccg gacgcgaccg gcgtgggctg
    32881 ggtctaccaa tatgccgtgc tcggcaagga catgagcctg gccgacacgc gcagcctgca
    32941 ggactggtac gtgcgctacc agctcaccaa ggcgcagggc gtgtcggaag tcgccagcat
    33001 cggtggcttc gtgcgcgagt accaggtcac cgtcgatccg ctgcgcctgg ccggctacgg
    33061 catcacgctc gaccaggtca cgcaagccat ccgcgcctcc aaccgcgacg tcggcggccg
    33121 cgtgctggaa ctcgccgaga aggagtacat ggtgcgcggg cgcggctacc tgcgcagcgt
    33181 ggatgacatc tccgacatcg tgttgaaggc cgagcgcggc acgccggtgc gggtgggcga
    33241 cgtcgcccgc gtcgaactgg tgccggccga gcggcgcggc atcgccgagt tgaacggcga
    33301 gggcgaggtc gcctccggca tcgtcatggc gcgcttcggc cagaacgcgc tcgacgtgat
    33361 cgccaacgtc aaggccaaga tcgccgagat cacgcccggg ctgccggcgg gcgccgagat
    33421 cgtgccggtc tatgaccgct ccgagctcat cgagcgcgcg atcggcaacc tcaagtggac
    33481 gctgctcgaa gagagcctga tcgtcgccgc cgtgtgcgtg atcttcctgc tgcatgtgcg
    33541 cagcgcgctg gtggccatca tcacgctgcc gctcggcatc ctgttcgcct tcatcgccat
    33601 gcgttcgctc ggcctgggct cgaacatcat gagcctgggc gggatcgcga tcgcgatcgg
    33661 agcgatggtg gatgcggcga tcgtgatgat cgagaacgcg cacaagcaca tcgagcgcct
    33721 gcccgagggc gccacccagc cgcagcgcgc agcggcgatc gtgctcgcct gcaaggaggt
    33781 cgggccggcg ctgttcttct cgctgctgat catcaccgtg tccttcctgc cggtgttcgc
    33841 gctcgaaggc caggagggcc ggctgttctc gccgctcgcc ttcaccaaga ccttcgccat
    33901 ggccggcgcc gcgctgctgt cggtgaccct ggtgccggtg ctgatgctgt tcttcgtgcg
    33961 cgggcgcatc ctgcccgagg cgaagaaccc ggtgaaccgg ctgctgatct ggctgtaccg
    34021 gccgatcatc cagggcgtgc tgcgcttcaa gctgctcacg ctcgtgctcg ccgtgctggc
    34081 gatggcggcc accatcgtgc ccgcgcgcca gatcggctcc gagttcatgc cgacgctcaa
    34141 cgaaggcacg ctgttctaca tgcctgcggc gctgccgggc atgtcggtga ccgaggccgg
    34201 gcgcctgctt gcgacgacga accgcatcat caagaccttc cccgaggtcg aatcggtcta
    34261 tggcaaggcc ggccgcgcca acaccgcgac cgacccggca ccgctcgaga tgttcgagac
    34321 ggtgatcaac ctgaagccgc aggaccagtg gcggcccggg gtaaccaccg acacgctgat
    34381 tgcggaaatg gacgccgcgc tcaagttccc cggtctcgcc aactcgtgga ccatgccgat
    34441 caaggcccgc atcgacatgt tgagcaccgg catccgcacc ccggtggggg tgaaggtgtt
    34501 cggcaaggac ctggagacac tggagaaggt cgcacaggcg gtggaagcgg cggtgcgcaa
    34561 ggtgccgggc gcgagcagcg cctacgccga gcgcgtggcc ggtggctact acgtggacat
    34621 cgtgccgcgc cgcgatcagc tcgcgcgcta cgggctcacc atcgacatgg tgcaggacgt
    34681 gatcgccacc gcgctcggcg gcgagatggt gacgaccacg gtcgagggcc tggagcgcta
    34741 cggcgtgtcg gtacgctacg cacgcggcct gcgcgacgat ccggcgcggc ttgcgtccga
    34801 cgtcttcgtg ccgaccatga acgggccgat cccacttggc cagctcgccg aggtgaagct
    34861 gacacgcggc gcgcccggca tccgcaccga gaacgcgctg ctggcggcct acgtgtatgt
    34921 cgacacccgc gaggccgacc tcggcgcctt cgtcaagcgc gcgcagcagg cggtggccga
    34981 ggaagtcgca ttcccgcagg gctactacgc cacctggagc ggccagttcg agaacatgga
    35041 gcgcgccaag gagaagatga agatcgtcgt gcccttcacg ctggcgctga tcttcgtgct
    35101 gctctacctc aacttcggcc gcctggccga gacgctgatc gtgatgctgt cggtgccctt
    35161 cgcgctggtg ggcggggtgt ggctgatgtg gtggctgggc taccagatga gcgtggcggt
    35221 ggcggtgggc ttcatcgccc tcgccggggt ggcggcggag acgggcgtga tcatgctgat
    35281 ctacctcgac catgcgtgga aggccgtttg cgagcgcagg caggccgaag gccgcgaggc
    35341 gggtgtcgcc gatctctacg aggcgatcat ggaaggcgcg gtggagcgcg tgcggccgaa
    35401 gatgatgacc gtggtcgcga tcatggccgg cctgttgccg atcatgtgga gcaccggtac
    35461 cggcgccgag gtcatgagcc gcattgccgc gccgatggtg ggcggcatgg tgtcctcgac
    35521 ggtactaacg ctggcggtga ttccggcgct gtatgcgctg gtcaagcagt gggggttgcg
    35581 ccgcagcgcc aagacagcac ccgcgcaggc gctggtcacg gtgtcgaatt tgtaatgcac
    35641 cggtcagcgg cgcgacagca tcgggggcgt agcctgtttc caaggccccg ttcccgaggc
    35701 cgccgctgaa cgtgacgagg agcattgcga tgcttgcctg gctgaaatcc ctctggcaat
    35761 ccttcaagaa ttggtgtcgc gagaacgagc gagcccaccg ggatgccccg ctctcgccgt
    35821 gctgctcgaa gccgcccgca gccgttcacc gttcgccgac ccgcaaggta tgaagccatg
    35881 aacacgaagc ctgctcatga tcctggacac cctcgatctg tcgcctggta tcgctccccc
    35941 ggcgtcatcg ctggcctgat gctggcggcg atcgcactgt tcttcctgct gcgcgaacac
    36001 tgggcgcatg tgtcgggcaa ctgggtgtat ctgatcctgt tgctgtgtcc cctgatgcac
    36061 ttgtttggcc atggcggaca tcacggcggg caccacagta acgacaccga ctcggagaag
    36121 cgctgagatg ccgatgacag aggcgtgcct aggccgtggc gtcgtcattg cggcgctttc
    36181 gggcgtcttg atttcgagcg cagcggcgca aggctggaag atcccgcagc cctctccggg
    36241 gctgatgccc aatccggggc agggaaaggg actctacgca cagcactgtg ccgcttgcca
    36301 tgggaccgac ctcaagggct cggacaaggg gccgcccatg ctccataagg tctacgaacc
    36361 cagtcatcac gccgatatcg cctttcagct ggcggtggcg aacggtgtgc gcgcccacca
    36421 ctggcagttc ggcgacatgg cacctgttcc cggcctgacg ccggacgagg tcgctcatgt
    36481 cacggcattc atccgggggg aacagcgcaa ggtcggcatt cgataacaac aatcgccggg
    36541 gagaggcatc atgacccacg agcattcgca gggcggccat tctggccaca accatcacca
    36601 cgatcatgca tcaccaggcc aggataccga tccggtctgc ggcatgaccg taaagcccga
    36661 ctctccgtat cgggtcattc acgccggaca cgaataccgg ttttgcagtg cgaagtgtca
    36721 aggcaagttc gagactgatc aggcgcggta tctggcaccg gagataggtc agccttcaac
    36781 ggaacccgca ctgctgcccg gcacggagta cacctgcccg atgcatccgg agatccgcaa
    36841 gactgggccc ggtacctgcc cgaaatgtgg catgacgctc gagccggtga tgccgggtct
    36901 cgaggatgag gacaatcccg agctcgccga cttccgtcgc aggttctggg ggacgctgcc
    36961 gctgacggtg atcgtcaccg cgatcgcgat gtccggcggt ctcttcgatt cgatgctggg
    37021 cgatacgcgc ccctgggtcg agttggccct ggcgacaccg gtcgtactct ggtccggttg
    37081 gccatttttt gtgcgttgcg cccaatcgat cggcaaccgc agcccgaaca tgtggacctt
    37141 gatcgggctc gggacgggtg cggcgtatgt gtatagcgtt gtcgccaccg ttacgccgga
    37201 gacgttcccg gattcgttcc ggatgggcga gcacgtcgcg gtgtacttcg aggcagcagc
    37261 ggtgatcatc tcgctgacgc tgctcggtca ggtgctggag ctaaaggcac gctcggagac
    37321 cggcgccgcg atcaaggcgc tgctcggcct cgcgcccaag accgcgcggc gaattcgcgc
    37381 ggatggcacg gaagaggaca tcccgctgac gcacgtccat cctggcgatc ggttgcgcat
    37441 ccgtccgggt gaaaaggtgc ccgtcgatgg ttccgttgac gaaggcgaaa gcgcggtcga
    37501 tgaatcgatg ctgaccggcg agccgatccc ggtgaccaag cgccccgggg acaaggtgat
    37561 cggcgccacg ctcaacacca gtggagcgct ggtcatggtc gccgagaaga tcggcgcaca
    37621 gaccatgctg tcgcagatcg tgcagatggt cgcgcaggct cagcgttcgc gcgcgccgat
    37681 gcaacgcctg gcggatgtcg tcgcgggctg gttcgtcatc gtcgtcgtgc tcatcgccct
    37741 caccacgttc gtggtgtggg gactcttcgg accccagccg agctgggcct acggcctcat
    37801 caacgcggtg gcggtgctga tcatcgcctg cccctgcgca ttgggcctgg ccacgccgat
    37861 gtcggtgatg gtcgcgaccg gcaaggcagc cacccagggc gtgctgtttc gcgatgcggc
    37921 ggcgatcgag tcgctgcgca aggtcgacac cctgatcgtg gacaagaccg gcaccctgac
    37981 cgaagggcgc cccgccttcc atagtgtggt ggcggcgccg ggcgggacgg aggccgacgt
    38041 gcttcgcatc gcagccagcc tcgatcaggg cagcgagcac ccactcgccc aggccatcgt
    38101 gaccgaggcc cgcgcgcgcg gtctggcgct cagcacaccg gacaccttcg aatcctcttc
    38161 cggcatcggc gtgcgcggta cagtcgatgg ccaacgtgtg gttctgggga acaccgccct
    38221 gatggacgat gagcgcatcg attggcgcgg gctcgcggaa cgcgccgagg ctctgcgcct
    38281 tgagggcgca agcgtgatgt acctcgccgc agagggcgtg ctcgtcggcc tcatcgccgt
    38341 tgcagatccg atcaaggctt cgaccccgga agcgctcgat gcgctgcggg cgagcgggct
    38401 caggatcatc atggccacgg gcgatgggct caccacggcg cgtgcggtcg gtgcccgcct
    38461 gggcatcgac gaggtctatg gcgaagtgaa gcccgccgac aagaatgagc tcgtcggcaa
    38521 actgcaggcc gaggggcgca tcgtcgccat ggccggcgat ggcatcaacg acgcgccggc
    38581 gctcgcgcgc gcgaatgtgg gtatcgcgat gggcaccggg accgacgtcg cgatgaacag
    38641 tgcccatctg actttggtca agggtgatct ccggggcatc gccaccgcac gccgcatctc
    38701 cgtcgccacc gtgcgcaaca tgcaccagaa cctcgtattc gccttcctgt acaacgcagc
    38761 gggtgtgccg atcgcagccg gggtgctcta tccagcgttc ggcctgttgt tgtcgcccct
    38821 gatcgccgcc ctggcgatga gcttcagctc ggcgtccgtg gtcggcaacg cgttgcgcct
    38881 cggacggaaa agggtctgat cgtcctcaat ccgcccgcac ggaaagctcg gcagacgaac
    38941 tgcgtgacgg gttcttcgtt cgttgggagg catgccggcg tcggcatgcc gatgtttgcg
    39001 cacaaggaac tgcctcatga aagccgagac tgaagtcgag ccggtaccac cggagcgggc
    39061 tgaatcaagt tcaagggttc gccgcgtatt tctggtcttc gtcgtactgg ctgccgttct
    39121 ccttatcgcc gagcaccggc tccatgtgct cggctaccta ccgtggctca tcttgcttgc
    39181 gtgccctctg atgcacgtct tcatgcatcg cggtcacggc cacaagggaa aacacacgcc
    39241 gactgaagac caaggtaacc atgatgcgta atgccacggg agatcgagat gaatgagacg
    39301 tcgagttacg gcttgtggtc actggtcatc atcaactcgc tgttcttcat cgccttcgcc
    39361 ttcagcttca cgcgtccccg cacaagccgg gactggcgat ccttgggcgc ttactcggcc
    39421 ttcatcctgg cgctcttcac cgagatgtac ggctttccgt tgacgatcta cctgctctcg
    39481 gggtggctgt cttcgaaatt tccgggaatc gatttttttg cccacgactc agggcacctc
    39541 ttggaggtca tgttcggatg gagcagtaac ccgcacttcg gcccgtttca cctcttgagc
    39601 accttgttca tcgtcggtgg cttctggctc ctggcaaagg cctggcccgt actcctcgag
    39661 gctcagcgca cccgccgcgt cgccgacagc ggcccctacg cccgcattcg acacccgcaa
    39721 tacgtcgcgt tcgttctggt catgttcggc ttcttgctgc agtggccgac cttgatcacg
    39781 ctgatcatgt tccctgttct gttgatcgtg tacgccaggc ttgcccgccg ggaagagctc
    39841 gacgcgatcg aggcgttcgg ggacgcctat cgctcatacc gcgagcgcac gccggcgttc
    39901 attcctcgcc tgcggtagtt cgatggaccg tttggtgccg agcgcagctt gcgaagtaga
    39961 gggagatgcc gccgcgcaga ttgctcattg tctgcaagca aggcgccttt gagcttgggg
    40021 ctccacgcat gcgtgcaggg cagagcgagt ttgatcaatc acacccgccg atcctgagaa
    40081 aggtagacag aaaaagcccc cgggatcgac accgggggca agttcatcct gaaacgcgcg
    40141 aatcagctac gggagtcgtg gcggaggatg ctgtcgagac gcatgacctc gtcgccgtgc
    40201 atcatgatct tctgcccatc cttggtctcc atcacttcgc cgtgcttcat cctcaccgca
    40261 cggcccatct tgtcctccat gcccattttc ccatccttga agatgtagac cgtcgagcca
    40321 tccttcatgg ggatggactt ttcgacccgc tcgacatcga ccgcgaaggc cgatgtggtg
    40381 gcaatcccaa gtgccgcgac catcagtgct ttcttcaaca tgctcgtctc cttgaatcaa
    40441 ctacaaataa ttgctgaaca ttgcatcagg cctcttccat agaagattgc ccgatgcctt
    40501 acccgccttg gttcctgggg aagcttggtg ctatcaggag ccgctgcggt aaagggggct
    40561 ttcttcgaga tagacagtca ccttgtcgcc cccttggacc accttcgaaa gcggaaagct
    40621 gtttgtgccg agggtgtcga aggtccagtt gatcgtcttg tcaccgacct tcagggcaac
    40681 cgtctcaagc cgcgtgacgt tgatgtagcg cgtgtccgca ttgacgatca cggtgcggga
    40741 gggtgtggcg ttgctcgcgt agccatacgt ggccagctct cgctcggtcg ggcttgaagc
    40801 gcgtgcctgg acatgctcga gccagtgcaa cgtaccgcgt ttggaatagt cttcgtgtgc
    40861 gaacgcagcg gaagatccaa ggctgctgat ggccgagacg gcgaggacgg cgatgatcga
    40921 ctttttcatg gtggctcctt gtccagttgt ccagattggc tgctcatgtt tgagcaacca
    40981 tggactcgat cataggagcc agcgactgac agggcagtga ccctacaatt acgtttaagt
    41041 cataagaatg aaagggtacg gtcagggttg gcgggctggg tttcgtcagc ccaaggcctt
    41101 gaccgaacgg cagacgcgca ttcagccggt tgatgacttg ggcaggctca cgaaacgggc
    41161 gagatagctc aaaaccaacc ttcccaagct gatgagtgtt gtttgatgtt tgaacgacaa
    41221 cgttctgttc tagctattag aaagctctgc ggcgacctcg caaaccgcat cagcatcggg
    41281 ataacggcca tccgagccac actcccgcct gctgctctcc ttgcctcgcc cccaaccttg
    41341 gtgcggcaac ggagttgcgt ccacgcgtgg gaggggcaat tctcgccacg gccctgacgt
    41401 atccaatcgt tgggaatttc ccgcaacaag ccggactcct gtataaaacg gccgacggat
    41461 cgccgaaggc gcccagccct cgcgaaaccg acccgacatg accgtgtttg cctcctcgtc
    41521 cgtcttctcg cgaaagatcg cccgcatgct ggtgaggggg gtgatcgggc tgctgatgct
    41581 gtcgcatgcg ctgttcgcgt tctcgagcgc gatctcgctg tctcacgacc ccttgcgtgc
    41641 aagcacgcac gcgcaggcgt ttgccgatgc agacacaggt caggacgatc atggacatcg
    41701 ccatgatgac ttcgaggacg agggcggccc ccaccaacac gggcacaacc cggccgatca
    41761 cagtcacgac aagccgaatg tgccgcccac gcacgcgatg ggtatcccac cgttgtccga
    41821 tcagtggctc gccgacgagc gtcgacccgc ctatcccgcg ccctgcgccc tgctcgagcg
    41881 cccgccaaaa cgtctcctga tcgtttgacc tgtcgagttc cgcgcgcgtg aagcgccgga
    41941 ctcacccagc aaacttcatc ggaagactct catgacgcat tccttcccca gccgggggcg
    42001 ggcagccgtg ctgccatgct ccgggccgct gctgcatgct ttcacaggcg tactgctcta
    42061 cctgctcctg accgctttcg cgcacgctca tggcgtggcc gagggcgaca agggctacat
    42121 ccaggagatc tcgggcacgc acctgctgcc cttcacctac cttggcgcca agcacatggt
    42181 caccggttac gaccatctgc tgttcctcgc cggggtgatc ttcttcctct acaagctcaa
    42241 ggacatcgcg ctctacgtca gcctgttcgc gatcgggcac tcggtcacca tgctgtacgg
    42301 cgtctacgcc ggggtgaacg tcaatgccta cctgatcgac gcgatcatcg gcctgtcggt
    42361 cgtctacaag gcgctcgaca acctcggcgc cttccagcgc tggttcggcg tgcagccgaa
    42421 caccaaagtg gcgaccctgg tcttcggcct gttccacggc ttcggcctgg cggccaagat
    42481 ccaggagttc gagatcgccc gcgatggcct attgcccaac ctgctggcgt tcaacgtcgg
    42541 ggtggagatc ggccagttgc tcgcgctcgg cgcaatcctg atcgcgatgg gcttctggcg
    42601 tcgtaccgcc ggcttcttcc agcacgccta taccgccaac gtcgccatga tgtgcgccgg
    42661 gttcatgctg atcggctatc agctcaccgg cctgttcgta tcctgagatt cctggagtca
    42721 tccaccatgt acaacaccga ccttcccaaa cgcgccgacc tgccgaccac cggcaagctg
    42781 ctgcgctcga ccgccctcgc tgccctgatc gccggcggac tgctcgtcac caccgtactg
    42841 cccgccgagt acggcatcga ccccacgggc atcggccgcg cactcggtct gacaccgatg
    42901 ggcgaaatca agatgtcgct ggcggctgag gcccgcgcag aagagcgcgt tgctacggaa
    42961 acggcgcccg cacagcccgt agccgtcgcc cctacggttc gtgccgaagc ggcgcctgtc
    43021 ccggcaccgg cgcccgtcgc ggtcgccgca ctgccgcccg cagcggtcgc gcccgagcct
    43081 gtcgccggac gacaagacac ggtgaccgtg acgctcaaac ccggtcaggg cgccgaggtc
    43141 aaactgacga tgaacaagga cagccgtgtc cgctatgagt gggcgagcgc cggtggcccg
    43201 gtgaacttcg acacccatgg cgacccctac gacgcgccga aaaacttcta tcacggctac
    43261 ggcaaggggc gtaacgagct cggcaaccag ggcgacctgg ttgccgcgtt cgatggcaag
    43321 cacggctggt tctggcggaa ccgctccggc ttcgacgtca cggtaacgct caagacccaa
    43381 ggcgattaca ccaaaatcga gcgcgtgctg taagcgcagc gcccccatcc cgccggggtg
    43441 ggggcgcttc cgatcattct ggccacaccg gtctggcaag ggcaatgaac aacatctacg
    43501 tgatccatgc gttgctcgcg gcggccttgt tcggcgcgag caccccgttc gccaagctgc
    43561 tggtcggcga gatgtcgccg tggttgctgg ccggcttgct ctaccttggc agcgggctcg
    43621 ggctggctgc gtcgcgtctg atccgcgatc gcagctggac gccctccggc ctggccgagg
    43681 gggaatggcg gtggctgctg ggggcgatct tcttcggcgg cgtgctcggc cccctcgcgc
    43741 tgatgttcgg tctcacgcgc acaagtgccg cgaccgcgtc gctgctgctc aaccttgaag
    43801 cggtactgac cgccgcaatt gcgtgggtcg tgttcaggga gaacaccgac cgccgcatcg
    43861 tgctcggcat gctcgcgatc gtggccggag gtgtcgtgct gtcctggtcg ggtggtgaag
    43921 agggcgcgaa cgattggatc ggtccgctag ccatcgccgc tggctgtctg tgctgggcaa
    43981 tcgacaacaa cctgacgcgg cgcgtgtcgg catcggatgc gctcttcatc gcggccacga
    44041 agggtgcagt ggcgggcacg gtcaacgtcg ggctggcgtt tgcgctcggc gcgagcctgc
    44101 cggacggcgc ggtcctgctc ggcaccatgg tcgtcgggtt gttcggctat ggcatcagcc
    44161 tggtgctctt tgtgcttgcg ctgcgcggac tgggcacggc gcgtaccggc gcctacttct
    44221 cgaccgcgcc cttcatcggt gcggccgtgt cgctggtcct gctcggcgag tcgacctcga
    44281 gcgcattctg gattgcggca gccctgatgg gctggggggt gtggctacac ctcaccgagc
    44341 accacgagca cgagcacacg catgagccga tggagcatgg ccatcggcac acccatgacg
    44401 aacaccacca gcacgaacac gacttcgcct ggaacagtga cgagccacat gagcattggc
    44461 accgccacga ggggctggtc cacaagcacc cgcactttcc agacatccac catcggcact
    44521 cacattgatt aaacgaagca ccaatttcac gtcgcccaac atgtcatgcg aggtgacggc
    44581 ttcactcggt tacttgccgt tcgcaccaca aagtgcccga cggctggttt gggtcg
//
LOCUS       DAOTIN010000017        43410 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_900_length_43410_cov_9.478099, whole genome shotgun sequence.
ACCESSION   DAOTIN010000017 DAOTIN010000000
VERSION     DAOTIN010000017.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 43410)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 43410)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43410
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_900_length_43410_cov_9.478099"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1016)
                     /locus_tag="P5537_04450"
     CDS             complement(<1..1016)
                     /locus_tag="P5537_04450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV77328.1"
                     /translation="MSERVPQGASEGLAGAPVHLRIERLGKRFGDAWAVREVSLDIGE
                     REIFALLGSSGCGKSTLLRMIAGLETPSSGRILLDGEDPAAVPAHRRPTNMMFQSYAL
                     FPHMTVADNVAFGLRQLRPRMARAAIAARVDEMLELVQMRAFARRRPQELSGGQQQRV
                     ALARSLAREPRLLLLDEPLAALDKRIRQQTQFELVGLIRRVGVTCILVTHDQEEAMTM
                     ADRIGILSEGGLVQVGTPGEIYERPNCRFSAGFIGETNLFHGRIEGDRLASSDFPQPI
                     VFAAGAGASPPSGGEAWLSLRPECVRVHRRAAGDACVAEHPGENVAAAEVAEIAYLGG
                     RSIY"
     gene            complement(1046..2134)
                     /locus_tag="P5537_04455"
     CDS             complement(1046..2134)
                     /locus_tag="P5537_04455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004307355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine ABC transporter substrate-binding
                     protein"
                     /protein_id="HRV77329.1"
                     /translation="MKLKFGWMAALALAAGVAVAAEEPILNVYNWNDYIAADTVPAFE
                     KASGIDVRYDLYDSNATLQGKLLTGGSGYDVVYPSVEYAGKQIQAGIFQPLDKSRLPN
                     LVHIDPLILEAVAVADPGNRHLVPYMWFTTGVAINVDKVMKALDGRLPENAWDLLFDP
                     ALTARLKGCGIALMDEASDVIPAAMLDAGLDPVRMDPADIRAAVEHIRPVRKHIRSFN
                     TAPIEQMAKGSLCVAMMFSGDARTAARRAQLAGAEIRLQYLIPSVGAMMSVDVMAIPR
                     DAPHPHNAHRWIDAMMDPATVARISNETFYISANTAALALTDATLRDDPVINVPEAVK
                     RTLRAKPVLGKDVQRELTQALNRFKAAR"
     gene            complement(2206..3513)
                     /gene="hisD"
                     /locus_tag="P5537_04460"
     CDS             complement(2206..3513)
                     /gene="hisD"
                     /locus_tag="P5537_04460"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004399 - histidinol dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HRV77330.1"
                     /translation="MSQTPIRRLDAREPEFLSTLDALLAFEAESDGRIDAAVTEILQA
                     VRTTGDAAVVEYTRRFDGLDVQSMVALELPKSELQLALDSLRPEQREALTIAADRVRV
                     YHERQKGESWEFTEADGTRLGQKVTPLDRVGLYVPGGRASYPSSVLMNAIPAKVAGVG
                     ELIMVVPTPRGEKNPLVLAAAAITGVDRVFTIGGAQAVAALAYGTQTIPQVDKIVGPG
                     NAYVAEAKRRVFGTVGIDMVAGPSEVLIISDGSGHADWVAMDLFAQAEHDELAQSILL
                     CTDTAFIDAVHEAIDRLLPTMPRRDTIARSLANRGALIHVDSLEQACALANRIAPEHL
                     ELSLDDAEAWIAHIRHAGAIFVGHWAVEALGDYCAGPNHVLPTMRSARFSSPLGTYDF
                     QKRTSIVNISQAGAQHLGKVASILAHGEGLQAHARSAEMRLKV"
     gene            complement(3524..4168)
                     /gene="hisG"
                     /locus_tag="P5537_04465"
     CDS             complement(3524..4168)
                     /gene="hisG"
                     /locus_tag="P5537_04465"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004336129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003879 - ATP phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HRV77331.1"
                     /translation="MSSITLALSKGRIFEETLPLLAAAGIVPTDNPESSRKLIIGTNR
                     PDVRLVIVRATDTPTYVQYGAADLGIAGKDVLVEHGGAGLYQPLDLNIAKCRLCVAVQ
                     KGFDYAAATRPGGRIRVATKYMNAAKAHFAGKGMHVDLIKLYGSMELAPLVGLADAIV
                     DLVSTGGTLRANNLEEVEDIMPISSRLIVNQASLKLKRELLQPVLDAFAGAIQP"
     gene            4321..4728
                     /gene="rnk"
                     /locus_tag="P5537_04470"
     CDS             4321..4728
                     /gene="rnk"
                     /locus_tag="P5537_04470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0070063 - RNA polymerase binding [Evidence
                     IEA];
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside diphosphate kinase regulator"
                     /protein_id="HRV77332.1"
                     /translation="MKPSIIVSSSDLERLEGLLTLPAFRSRSDLDGLREELERADVRE
                     PQDMPADVITMNSRARFVEEGTGREYELTLAYPKDANAEAHRVSIFSPAGSALLGLSA
                     GQSIDWKSSDGKEIRLRVLEVTWQPEANGQFEL"
     gene            complement(5007..6257)
                     /gene="murA"
                     /locus_tag="P5537_04475"
     CDS             complement(5007..6257)
                     /gene="murA"
                     /locus_tag="P5537_04475"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015434400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HRV77333.1"
                     /translation="MDKLLIEGGARLSGEIAISGAKNAALPILCAALLSAEPVTFTNV
                     PCLNDIDTLLALLGQMGVRVKREADVVTLDASALDNPVAPYEMVKTMRASILVLGPLV
                     ARCGEARVSLPGGCAIGARPVDQHIKGLQAMGAEVRVEHGYVHATVPRLKGARLFTDM
                     VTVTGTENLMMAAALADGETVIENAAREPEVVDLANCLVAMGAQISGAGSDVIRIRGV
                     ERLHGATHRIMPDRIETGTYLCAAAVTGGSVRLTGTSSCYLDAVIDKLMDAGCEVVSE
                     RDAIRLSAPARLNAVSLRTAPYPAFPTDMQAQFMAINAVAKGVAMIRETIFENRFMHA
                     VELQRLGADIRIDGNTAVVQGVDTLQGAIVMATDLRASASLVVAGLVAEGETTIERIY
                     HLDRGYERLEEKLAALGAKVRRLA"
     gene            complement(6265..6522)
                     /locus_tag="P5537_04480"
     CDS             complement(6265..6522)
                     /locus_tag="P5537_04480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BolA/IbaG family iron-sulfur metabolism protein"
                     /protein_id="HRV77334.1"
                     /translation="MFEASEVKRLIEQGLPCELVVIEGEDGVHFRGIVVSAAFEGKMK
                     VRQHQAVYATLGRLMGNEIHALQLQTFTPAQWEEGRGELGM"
     gene            complement(6533..7306)
                     /locus_tag="P5537_04485"
     CDS             complement(6533..7306)
                     /locus_tag="P5537_04485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004307366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV77335.1"
                     /translation="MAAESPLAGFRTLLYKEVLRFWKVSFQTVGAPVLNALLFLLIFS
                     HVLDRHVTVYGEVAYTSFLVPGLVMMSVLQNAFANSSSSLIQSKITGNIIFVLLPPLS
                     YREFYAAYVIASTLRGLMVGAGVLAVSAAFVEVPMAHPLWVLGFAVLGGAILGSLGVI
                     AGIWADKFDQLAAFQNFLIMPLTMLSGVFYSIHSLPQFWQDVSHFNPFFFMIDGFRYG
                     FFGQSDTSPWLSLGVVGLCFVLLAALTLAMLARGYKLRS"
     gene            complement(7341..8237)
                     /locus_tag="P5537_04490"
     CDS             complement(7341..8237)
                     /locus_tag="P5537_04490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV77336.1"
                     /translation="MSTPAIRIQGVSKHYGSLKALGGVDLEVGQGEFFGLLGPNGAGK
                     TTLISALSGLVRPDGGTLAIMGHDVVADYRNARRNLGVVPQELVFDPFFSVRELLRIQ
                     SGYFGIRSNDDWIDEILASLDLAHKANANMRMLSGGMKRRVLVAQALVHRPPVIVLDE
                     PTAGVDVELRQGLWQFIRKLNRDGHTIVLTTHYLEEAEALCGRIAMLKAGRIVALDTT
                     ANLLRRFATHSLAVRLEHPGRGVELGGSAGEGGWVDFAFDSYTEVEALLARLREAGAG
                     LVEMRLGEPDLERVFVEVMNRA"
     gene            complement(8234..8518)
                     /locus_tag="P5537_04495"
     CDS             complement(8234..8518)
                     /locus_tag="P5537_04495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HRV77337.1"
                     /translation="MSDPAVFAPEGALTMQRAPALLAEGQRRARAGDLVVDLAAVSAA
                     DSAALALILDWMRCARAAGHALVLRNPPAGLASLAALYDIDGLLPLERAA"
     gene            complement(8515..9177)
                     /locus_tag="P5537_04500"
     CDS             complement(8515..9177)
                     /locus_tag="P5537_04500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HRV77338.1"
                     /translation="MNKILDFLRVFLLCALFGAALPAAASADKAPDLLVRDVTNEVLE
                     IVRADTAIQAGDTRRVIELVDAKVLPHFDFRRMTMLAVGRDWRQASAEQQGRLTDAFR
                     TLLVRTYSNALTQYRDQRIEFRPSRFAPADTRVQIRTEVVQAGAQPIGIDYMLEKSEQ
                     GWKVFDVIVAGVSLVTNYRSSFGQEIARGGIDGLIRSLEERNRALAEQQGMSQAGAGR
                     GA"
     gene            complement(9187..10038)
                     /locus_tag="P5537_04505"
     CDS             complement(9187..10038)
                     /locus_tag="P5537_04505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004307374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VacJ family lipoprotein"
                     /protein_id="HRV77339.1"
                     /translation="MRNVFRSSRASLAAAAISAALLGGCATTGNPDDPLEGYNRAMFS
                     FNEQLDKVAIKPAAQVYEAVLPSPLRTGVGNVLGNLGDPWIALNNVLQGKVAEGMSDL
                     MRFALNSTWGLLGLLDIASEAGLPKHDEDLGQTLGRWGVGEGAYIVLPFFGPRTVRDA
                     VALPADMMGNEPFSIDHVPTRNTVLGTRVVHGRSVLLGADRTLEEAALDRYAFVRDFY
                     LEQRRYKVSDGRQERVYEDFDEQSAAPLGGEVDAAAATAVENLELAGIGATPATTGRR
                     VTRQTIQ"
     gene            complement(10067..10534)
                     /gene="mlaD"
                     /locus_tag="P5537_04510"
     CDS             complement(10067..10534)
                     /gene="mlaD"
                     /locus_tag="P5537_04510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002928504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015914 - phospholipid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipid asymmetry maintenance
                     protein MlaD"
                     /protein_id="HRV77340.1"
                     /translation="MSRTALDLWVGIFVAIGFAALVFLAMKVGNFSGLDGSETYRVEA
                     PFDNIGGLKVRAPVKSSGVLVGRVAVIRFDPAIYRAVVELEIDKRYAFPADTTASILT
                     SGLLGEQYVGLEAGADGEMLKNGDRVLITQSAVVLEKLIGQFMFDRAADAPAQ"
     gene            complement(10537..11325)
                     /gene="mlaE"
                     /locus_tag="P5537_04515"
     CDS             complement(10537..11325)
                     /gene="mlaE"
                     /locus_tag="P5537_04515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid asymmetry maintenance ABC transporter
                     permease subunit MlaE"
                     /protein_id="HRV77341.1"
                     /translation="MNAIASALRRIGALTIDGVWRLGFATRFLLAVLLNSGQSLRRIH
                     LTIRELYFSGVLSLLIIMVSGLFVGLVLGLQGYDILQRYGSADAVGVMVALSLLRELG
                     PVIAALLFASRAGSAITAEIGLMKTTEQLKAMDMMAVNPIARVVAPRFWGGVLSMPLL
                     AALFSAMGIFGGWLITVVVIGVDDGAFWSQMQAAVEFRYDVVNGVIKSAVFGTVVSLI
                     AVFEGYDCQPTAEGVSRAITRTVVTSALAILALDFVLTSFMFRG"
     gene            complement(11322..12143)
                     /locus_tag="P5537_04520"
     CDS             complement(11322..12143)
                     /locus_tag="P5537_04520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV77342.1"
                     /translation="MSVSAPHPSPLVSLRDVRFAYGEREVLRGIDLSVHRGQVVAIMG
                     GSGCGKTTLLRLIGGQLRATAGTVEVEGRDVARLSGAELYALRRRMGMLFQFGALFTD
                     MSVFDNVAFPLREHTELPVGMVRDLVLMKLQAVGLRGAAKLHPNELSGGMARRVALAR
                     AVALDPMLILYDEPFAGLDPISLGIIGQLIRKLNDALGASSVMVTHDVHESLAIVDYI
                     YFVSDGRIVAQGTPDEIRASRDPFVHQFVHAEADGPVPFHYPAEPIDRLLGGESA"
     gene            12338..14218
                     /locus_tag="P5537_04525"
     CDS             12338..14218
                     /locus_tag="P5537_04525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_process: GO:0009297 - pilus assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="secretin N-terminal domain-containing protein"
                     /protein_id="HRV77343.1"
                     /translation="MTFQLHGLHRLITAATLLATAGCVPLTRPPALEGHLDQRTAIDR
                     PEHTRSTARPHAPTSTAASPAGPSAAPQDRTIQPPPTRQHGRPERGYSVDVYDIPAEQ
                     LLLAIGRDAGLELDLHAGITGKVSLQAHDRPLGELLERIARQVDLRYELRGRHLRVRP
                     DTPFIRSYAVDYVNLSRDMRGTVATSTQIATSGSGGAGQRTSSAGGAGNASITQIETR
                     AANDFWNTLEHNLASILAGPGRAPDCGGERASERAGGCRNADLMLNRESGIVMARATA
                     RQHEQLEAFLAGVQRAARRQVMIEATIVEVTLADGYRQGIDWTRLGVPGWSVRPRGSG
                     DATPGQPTLSYLSANSDIRLELLETFGTVKVLSSPRLSVLNNQTAMLKVVEEVVYFLV
                     DSTTTEYDDRKQARISATTTPQSVSVGMVMSVTPQISADGDITLNVRPTISGISGFKD
                     DPNPSLGDIPNRVPQIRTREIESMLRLRSGEVAVLGGLMEDRLDHDTGRIPLLGDLPV
                     VGELFTRRDNNVRRTELLIFLRPLLIDEPGMRGGYAEYAGRLPDDDFLLDSPSPGQRN
                     FPHLPLRPLLAPAGTAPVADGLSDAAYPDAAVLHSSDPRPSHPSSPSARSARAAAATS
                     PP"
     gene            14215..15936
                     /locus_tag="P5537_04530"
     CDS             14215..15936
                     /locus_tag="P5537_04530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004307383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GspE/PulE family protein"
                     /protein_id="HRV77344.1"
                     /translation="MNAPLPIGQTLIAAGLIGEDQLRIALHEQRGRSQPLGRVLVELG
                     FVSEAALREALAARSGLPCVDLATALADPDAIARVPQALARRHRLLPLQYDAARHRLI
                     VAMADAHDIVALDRLRAELGPDVHVELRLAGDSELGRAIEQHYGQASSIEDMVRELER
                     RAGQPVTGARDPQLVVRLVDALLAEAAARAASDLHLEPEAGFLRVRHRIDGTLRQVRA
                     MHKSCWPELAVRIKVLAGMDIAESRSPQDGRIGLAVGGRPIDFRVATQPTLHGENIVL
                     RILDRDKGIVPLDALGLDPAQSSALHRILARPEGLILVVGPTGSGKTTTLYSMLGHLN
                     TEAVNIMTLEDPVEYPLALIRQTQVGEASRLDFADGVRALLRQDPDVILIGEIRDADT
                     ATMALRAALTGHQVFATLHANSIFGALPRLHEIGIGPELLAGNLCGILAQRLVRRLCA
                     ACREPVPDDAPERRLPGLADAAPPPPSWRARGCPECDFRGYRGRLAIMEILPFDAALD
                     ELVARRASPGELRAAARACGHRSLAEDGLRRVLDGSTSLAELARVVDLSALAAMPAAD
                     VAQGGIA"
     gene            15933..17135
                     /locus_tag="P5537_04535"
     CDS             15933..17135
                     /locus_tag="P5537_04535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004307385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HRV77345.1"
                     /translation="MSSWRYRALAADGRRVRGELDAADLRELERMLEARALLLLDARP
                     RGTLSLLQRRRIPRSELIPFCYHLEQLLAAGVPPFESLAALRDAGAEPRLQQVIDALI
                     TDVERGLPLSGAAARQPEAFSAVAVSLLRAGEQAGRLPEAIRDIGAALAQEEELAGHA
                     RRIAIYPSIVATVLLAAVVVALVHVVPELERLLRGTGQRLPLQTRILMGLSGAVRDWG
                     WAMLLCTLGGTALGAHALARSEPLRTRLHALQLRLPLVGGILRKLALARFAALFATLY
                     GAGINVIEALHTSTGATANLALRAGLREATGAIEQGRPISVAFEATQVFPPLVIRMLR
                     LGEHTGALDDALTKVASLYRRDVAEGIARLQAAAEPVLTILMGGLLLWIASAILGPIY
                     ELITRLPV"
     gene            17138..18727
                     /locus_tag="P5537_04540"
     CDS             17138..18727
                     /locus_tag="P5537_04540"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77346.1"
                     /translation="MRREPLLLAVASSGLLACSGHEEGIRLLAAFMPGDEAAFASWLA
                     RRAPDEPCRVLVDLPDEAYEIEDLPRVRGGDRRALFARRLAHWFPEPRFARAWSLGAP
                     SEGRKGFERVLFSGLERSAELMPWLERLEADGRRPELLAPAAALLPRLPLPGARQRRR
                     SKGPSRPRLVAASGRAGLRIALLDREHTLFSRLLRAHAETLSDPQALASEFERTRDYL
                     VAQHRIASDTPLDRIAVDLPAHPGAEQATLAPVGIVAADTLAVGTPPSGYDAHLLLAL
                     RRAPATIGWPLATLARRWPGLAGRRVFAALGIAVAMLLGGFVWMDRLAQAEAEALAAA
                     ERARAARTAALAAEEAERTAREAERAALAALDVAPPAPLPPTVAAPEPEPPAIPVPTP
                     ATCPPASSPPPLPIPRRIDGILRRPDGEVLLWVEGSWQSARSLGLRPTAGDAAAVSPA
                     GRRTRLRSGDSLPVELSTRAIGAVQPHPEQDQPAPTAREGSSSTHPAEHGSGAAGSAL
                     AAPESSLLTAKPALAASGAQP"
     gene            18724..20046
                     /locus_tag="P5537_04545"
     CDS             18724..20046
                     /locus_tag="P5537_04545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002928489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77347.1"
                     /translation="MTVPGGLRAPQRHDRLPQAIAKAFAPTGARRDVAAAHGQALIAA
                     LLLLTLLAAGGLLAGGELRARAHALAHARSVEALAIARAALIGYAISYAETHPGEGYG
                     FLPCPDAGNTGSTPVGACGARGIAAVGRLPWRTLGLPELRDGWGECLWYAVAGSVKHN
                     PKPQALNWDSPGQFRLLDPAGRALEVAAADGMAVAVVFSPGPPRSGQTRPASLGTHCT
                     GSDSAAADLAHYLDPGHARAGSGPIELTLHPATLDDAAPNDLAAWIGIDDLFDALRRR
                     RDHAGHVDAILTRSANALAGRLASNREAWLSRHARSVGALATGVLPAAETLGIAAAQR
                     PLIDDWREQIRFAACTDGSACIGVVRPAAPGERCRAVLAFGGERTRGDPGRQMRTTPA
                     ERADPSAWFEGRNVAALHLGVPEFEGGEHFRVTDPDRPATEDVVRCLP"
     gene            20034..20819
                     /locus_tag="P5537_04550"
     CDS             20034..20819
                     /locus_tag="P5537_04550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HRV77348.1"
                     /translation="MPALTPATDPMHLLAPAGRRPLLQRPGEPARHAPGHSRSAPGRG
                     IARGFTLVELAMVLVILALLGGSLLVPVASRLEARDRNATLERLRDIQHALTGFAIIH
                     GRLPCPSTETDPANPAYGLEDGPPCNLAREGVLPWRSLAMPATDAWGRDRHTAADDWA
                     GHWRYRVDPAFSVAPIGAATAPSARLQIRDHDGRRITTTDSQAVAIVWSTGANLRADG
                     DNSSHASATPSYQAGEPGADFDDLLAWIGRPLLIARLAQAGRL"
     gene            20887..21528
                     /locus_tag="P5537_04555"
     CDS             20887..21528
                     /locus_tag="P5537_04555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HRV77349.1"
                     /translation="MTRKPQTGFTLVEIAIVLLVVGLLLGGVMKGQALIDSARVKNLA
                     QDLRSVPAMIHAYQDRFRALPGDDPAAVRHLCSGGGACTVAGNGNGVINGDWDAGADT
                     ESVRLWQHLRLAGLATGSTDTADAGFLPRNALGGRVGVQRGGSVLGLPGSLVVCSDNV
                     PGKLVTQLDIALDDGDPAAGSLRAGSPGDSGLVAISAANPLLEANAHTVCSNL"
     gene            complement(21558..23525)
                     /locus_tag="P5537_04560"
     CDS             complement(21558..23525)
                     /locus_tag="P5537_04560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HRV77350.1"
                     /translation="MLNTLEFVVLLLAAAVVMVAFFRSMNLPPVLAYLLVGALGGPHA
                     LDLMQESAGARHLAEFGVVFLMFSIGLEFSLGRLMAMKRIVFGLGLAQVLATIALVTL
                     LGRLGGLGWITAFALGGTLAMSSTAILSKLLADRMELDSRHGREVIGVLLFQDIAVVP
                     LLILLPALSRPAEEMMFTLGLAAFKVVFLLSLVLVFGQRLMRWWFTVMARRRSGELFM
                     LNVLLITLGLAWLSELVGLSLALGAFLAGMLISETEYRYQVEEDIKPFRDVLLGLFFV
                     TVGMLLDVAEIVRNLPAVLGLLAALLVLKFGVVFAASRLFGSPAGTAMRSGLWLCAGG
                     EFGFVLLSQILELGLMPYGLAQATVAALVLSMLVAPLIVQVSDRLVMRFVASEWLLRS
                     MELTRVAAQSLNTERHIIVCGYGRSGQYLARFLEQENVAYVALDLDPERVREAGAAGD
                     TVVYGDAARRETLIAAGIQRASALVVSFDALEAALRVIHHAHALRPGLPVVVRAGDEA
                     DLEKLAQAGAAEVVPEAFEASIMLASHALALTGVPLSRVVRRIREIRSQRYALMRGFF
                     QGSSDAGDGGDGAEARLRSVIVPEGAAGVGRSIGELGLEEFGVAVSAVRRRGIRALSP
                     AAETRIESGDVIVLLGVPGSLEAAEERLLGG"
     gene            23679..24668
                     /locus_tag="P5537_04565"
     CDS             23679..24668
                     /locus_tag="P5537_04565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="KpsF/GutQ family sugar-phosphate isomerase"
                     /protein_id="HRV77351.1"
                     /translation="MDPISASGESRAVALARRVLRIEADAVAALGARVGEEFERAVEI
                     ILARHGRVIVTGVGKSGHIGRKLAATLASTGTPAYFVHAAEAAHGDLGMITPEDVVIA
                     LSNSGSSEELLTIVPLVKRQGARLIAMTGKPDSPLAREADAHLDAGVGEEACPLNLAP
                     TASTTAALALGDALAVALLDARGFAAEDFARSHPGGALGRRLLTHVGDVMRPAAAVPR
                     VGSDAPLTQALLAMTAGGMGMTAVVDADDVPVGIFTDGDLRRALEKGRDVRSARVSEV
                     MTRNPRSIAPGALAAEAAATMENLRISQLLVLDQAGRLAGALTTHDLMLAKVI"
     gene            24669..25250
                     /gene="lptC"
                     /locus_tag="P5537_04570"
     CDS             24669..25250
                     /gene="lptC"
                     /locus_tag="P5537_04570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015221 - lipopolysaccharide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015920 - lipopolysaccharide transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter periplasmic protein
                     LptC"
                     /protein_id="HRV77352.1"
                     /translation="MRVDTWRLYPVFALAVLAGGSVWLERITRIDDPVTSAEQTGPDF
                     IAHDTRVVGFSALGARRYELVAERLEHFPASDITRLHQPRLQLHGEEGTTTITARAAD
                     VSPGGEQVDLAGEVRVRRPGQAGALPLALDSETLTVWPDAQRARTDSPVLMTRGTARA
                     SARGMRADNLFGTLELIGEVSTTMPPRRQGSPS"
     gene            25247..25786
                     /gene="lptA"
                     /locus_tag="P5537_04575"
     CDS             25247..25786
                     /gene="lptA"
                     /locus_tag="P5537_04575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0001530 - lipopolysaccharide binding
                     [Evidence IEA];
                     GO_process: GO:0015920 - lipopolysaccharide transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide transport periplasmic protein
                     LptA"
                     /protein_id="HRV77353.1"
                     /translation="MKQLLIATAAALLVAASPALAEKADRDQPVNIEADRLTVDDRNK
                     VHIFEGNVILTQGTLTIRGDKLVVTQDAAGFQNGVATAAGKGLATFRQRRDGSAEYVE
                     GEAERIEYDSRTEKARLFNRAKVTSGGDQVAGHYIEYDAITENYLATNAPGSRQGAPA
                     GRVRAVIQPKSDGQPAGTQ"
     gene            25824..26600
                     /locus_tag="P5537_04580"
     CDS             25824..26600
                     /locus_tag="P5537_04580"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HRV77354.1"
                     /translation="MSFEMIIAEKRGRVGLITLNRPKALNALNDQVVNEITAALNDFE
                     SDDGIGAMVITGSEKAFAAGADIGAMASFSYMDAYKSEYITRNWERVKTCRKPVIAAV
                     AGFALGGGSELAMMCDIIIAADTAKFGQPEVKLGTLPGAGGTQRLPRAVGKAKAMELC
                     LTGRMMDATEAERAGLVARVVPADKLLEDALATAETIAGYSLPVVMMIKESINRAYES
                     SLNEGLLFERRVFHASFALNDQKEGMAAFVEKRKANFRHD"
     gene            26928..27494
                     /locus_tag="P5537_04585"
     CDS             26928..27494
                     /locus_tag="P5537_04585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phasin family protein"
                     /protein_id="HRV77355.1"
                     /translation="MSNFVTPEQFAAANKTNIETLLTLANTAFASAERLAALNLNTAR
                     SLLEDGVANTKALLAAKDVQELVNLQVSLAQPIVEKAVAYARSVYEISSQSQEEMSKV
                     FEGQVAEMNKGVATALDKAAKSAPAGSDVAVAAVKSAIAAANSAYDSMSKAAKQVAEI
                     AEANVAAATNATVKAVSTTAKTAAKKAA"
     gene            complement(27603..27974)
                     /locus_tag="P5537_04590"
     CDS             complement(27603..27974)
                     /locus_tag="P5537_04590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4a-hydroxytetrahydrobiopterin dehydratase"
                     /protein_id="HRV77356.1"
                     /translation="MSEEIRALDEEEILAGLAGLAHWRLEAGCLVRDYRSGGWKATLM
                     VAGVVGHLAEAAWHHPEMELSWDRVRVRLSTHSPRGITARDLALARKIEEVVQWQPAS
                     EGGALEGTPNADERFRYIRYD"
     gene            complement(28039..28815)
                     /locus_tag="P5537_04595"
     CDS             complement(28039..28815)
                     /locus_tag="P5537_04595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HRV77357.1"
                     /translation="MHLIRSILFAILLTVITVPYAFLATFIFWLPPMTRHRLITSWVP
                     IMMWVIRHVLGIRYRVIGAENIPAGPAVVLSKHQSAWETIALQVIFPPLCYVLKRELL
                     RVPFFGWALGMIPGIAIDRSAGKDALTQVVEQGRERLKEGLWVVVFPEGTRVAPGATR
                     RYKPGGAILAKRAGVPVVPVAHNAGEFWRRNAFIKRAGEIVVSIGPVIEVKGVKANDV
                     SEQAEAWIEGEMRRLFPHHYQDEAGAPPLADEAAAEAGGN"
     gene            complement(28874..29407)
                     /gene="gmhB"
                     /locus_tag="P5537_04600"
     CDS             complement(28874..29407)
                     /gene="gmhB"
                     /locus_tag="P5537_04600"
                     /EC_number="3.1.3.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-beta-D-manno-heptose 1,7-bisphosphate
                     7-phosphatase"
                     /protein_id="HRV77358.1"
                     /translation="MKLIILDRDGVINVDSGQYIKSPEEWKPVPGALEAIARLNQWGW
                     RVVVATNQSGIGRGLFGMDTLNAINDRMVKSLAQAGGRLDGIFFCPHAADSTCDCRKP
                     KPGMLLQIAERFNVELADVPCVGDGLRDLQAAAAAGAKPYLVLTGKGEATQASGELPP
                     GTQVYPDLDAVAAALTA"
     gene            complement(29466..31553)
                     /gene="glyS"
                     /locus_tag="P5537_04605"
     CDS             complement(29466..31553)
                     /gene="glyS"
                     /locus_tag="P5537_04605"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009345 - glycine-tRNA ligase complex
                     [Evidence IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HRV77359.1"
                     /translation="MTAATLLVELLTEELPPKALPRLGETFATKIAEGLKARGLAPAD
                     APFRTFASPRRLAVTVAQVASEAAAKEVTEKLMPVSVALDAEGKPTPALLKKMEAKGI
                     PADAVGSFERRMDGKAEALFHTATVAGARLADVLAGIVQDAIKALPIPKVMRWGDGDA
                     TFVRPVHKLTLLHGADVVPGRVLDLDSGRTTRGHRFMSRGEIDIATADAYEPTLLAEG
                     KVIPSFAERRADIERQLLAEAARQGALLNEYADLLDEVAALVEHPTVYVGEFEAEFLA
                     VPQECLILTMRANQKYFPLFDGAGKLLNRFLIVSNMQVADPSNIVAGNARVVRPRLSD
                     ARFFFEQDKKQPLAARLPRLAPVVYHNKLGSQLERVERLEALAGAIAAQLHGDVAAAE
                     RAARLAKADLVTDMVGEFPELQGIMGRYYALADGEGQVVADAIQAHYQPRFAGDALPA
                     GNVAAAVALADKLDALVGFFGIGMVPTGDKDPFALRRAALGVLRILMEAPLPLELPWL
                     VDTAAAGFKPGLLTAEGFAAQLQDFMFERLKNLLRESGRDGAVIDAVLALKPARIDLV
                     PAKLAAVEAFRALPEAEALAAANKRIVNILRKVEAAPGEPDLALLQEAAEKALFHQVV
                     EVAPLVRSHVANEDYTDALCALAGLRAAVDRFFEDVMVMAEEPLTRANRIALLAQLAG
                     LMNQVADISRLSA"
     gene            complement(31553..32479)
                     /gene="glyQ"
                     /locus_tag="P5537_04610"
     CDS             complement(31553..32479)
                     /gene="glyQ"
                     /locus_tag="P5537_04610"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009345 - glycine-tRNA ligase complex
                     [Evidence IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HRV77360.1"
                     /translation="MTTESRLVKPTFQQVILTLQHFWGERGCVLLQPYDLEVGAGTSH
                     TATFLRAIGPEPWNAAYVQPSRRPKDGRYGENPNRLQHYYQFQVVLKPSPLNIQELYL
                     DSLRALGIDPTVHDIRFVEDDWENPTLGAWGLGWEVWLDGMEVTQFTYFQQVGGLDCK
                     PVLGEITYGIERLAMYLQGVENVYDLVWSVGPDGRAVTYGDVYHQNEVEQSTFNFEHS
                     NVDFLFSLFANYESEAKRVMEVGLPLPAYEMVLKAAHTFNLLDARGAISVTERAAYIG
                     RIRNLSRAVAQAYFESREALGFPMLNVTKEAA"
     gene            complement(32528..34054)
                     /gene="lnt"
                     /locus_tag="P5537_04615"
     CDS             complement(32528..34054)
                     /gene="lnt"
                     /locus_tag="P5537_04615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016410 - N-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006497 - protein lipidation [Evidence
                     IEA];
                     GO_process: GO:0042158 - lipoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="apolipoprotein N-acyltransferase"
                     /protein_id="HRV77361.1"
                     /translation="MRSAWLVALLAGGATVFAFAPFGLFALAFLGLGVLAWLLADAAR
                     ARAGFALGFAWGFGAFAAGVSWLYVALERYGGVPAPVAALAIGLFCAYLALYPALAGA
                     AFVALRRGGIARAPVRAAALFGALWLLSEWLRGVVFTGFPWLAVGYAQTPPSPLAGLL
                     PVLGVYGVGGLSAFVAALCAFALRAGGVRALLAWRPALALVVPFAAGFALLGQAWTQP
                     AGAPLKVALVQTDFAQSLKWDPARFEEVLRVNLELAREAFAQPQTPALVVLPETTLPT
                     LLDRLPEGYLEVFAGLASQAGGDLVMGAFRRDAEERIYNAAISLGSAPVQRYAKQHLV
                     PFGEYSPPLFGWFYELAQIPMSDQTRGAPDQQPMRFGDQQVALNICYEDLFGAELIRA
                     LPAATLMLNLSNLAWYGDSLAQPQHLQIARVRALETGRPMLRSTNTGMTAVVQPDGSV
                     AAVLPAFERGVLHAEVRGHQGTTPYARWGDRLALLAAVIPILLAALAAAARPRGAEAR
                     "
     gene            complement(34054..34893)
                     /locus_tag="P5537_04620"
     CDS             complement(34054..34893)
                     /locus_tag="P5537_04620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter associated domain-containing
                     protein"
                     /protein_id="HRV77362.1"
                     /translation="MDSSPKPSLLERLSALLSREPEDRDELLALLHSAFDRNLIDADA
                     LTIIEGALQMSDMQVRDVMIPRAQMDCIHLDDPIDTIANFAIDTAHSRFPAIGDGKDD
                     VVGILLAKDLLRYFAGREFDLRDMLRPAVFVPESKRLNVLLREFRVSRNHMAIVVDEY
                     GGVAGLVTIEDVLEQIVGDIEDEYDFDEVGDNIRLDHSGRYRVKATTEIEDFNEAFAT
                     HFSDEEYDTVGGLVIRHFGRLPKRGEAVELEGLRIQVLRADSRRVYTLIVERLPQPLP
                     EQA"
     gene            complement(34916..35749)
                     /gene="ybeY"
                     /locus_tag="P5537_04625"
     CDS             complement(34916..35749)
                     /gene="ybeY"
                     /locus_tag="P5537_04625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HRV77363.1"
                     /translation="MANKTNKTNKTDKTNKTVADRSAGTYPRIVAIDAEGKAARVRAE
                     RLEIELGDGRKLLLAFPEKAWGDLEIEAEADDDSAVPMLSLQPGACNLMTLRVDVHHD
                     LSFVEPLALPAGEHSPVLKLQVQKAVEGEDKANCPKKNHIRRWATAALRASAQVTVRL
                     VGEAEGRALNRDYRGKDYATNVLTFAYAEGEALPGLPEAGGDVPLAGDLVLCVPVVVR
                     EAAAQGKTLEAHFAHLVVHGMLHLQGYDHENETEAAEMEALETAILRELGYADPYALS
                     A"
     gene            complement(35739..36758)
                     /locus_tag="P5537_04630"
     CDS             complement(35739..36758)
                     /locus_tag="P5537_04630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HRV77364.1"
                     /translation="MAKTLEVFFEPVDNARLAKLCGVLDENLRQIENAFDITVSRRGE
                     HFTLAGHPAQVLRGEMALKHFYALADKDLSRDEVQLGLIEIASKGEAAQPAPVLLTRR
                     TELHGRTPRQVDYLRNIQDFDITFGIGPAGTGKTYLAVASAVDAFERDLVERIILTRP
                     AVEAGERLGFLPGDLAQKVDPYLRPLYDALYDLMGFDRVGKLFERGSIEIAPLAFMRG
                     RTLNNAFIILDEAQNTTPEQMKMFLTRIGFGAKAVVTGDLTQVDLARGQRSGLKEARA
                     VLAGVRGIAFTEFSKEDVVRHPLVARIVEAYDLEAARLEREKAAARAARQQPEPQEQE
                     AEDGE"
     gene            complement(36759..38111)
                     /gene="miaB"
                     /locus_tag="P5537_04635"
     CDS             complement(36759..38111)
                     /gene="miaB"
                     /locus_tag="P5537_04635"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004336071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016782 - transferase activity,
                     transferring sulphur-containing groups [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HRV77365.1"
                     /translation="MKKLYIRTFGCQMNEYDSDKMADVLGAHEELVKTDNPEEADVIL
                     FNTCSVREKAQERVFHDLGRVRLLKQQKPGLIIGVGGCVASQEGEAIVKRAPYVDVVF
                     GPQTLHRLPSLIEARKQSGRSQVDISFPEIEKFDAMPPARVEGASAFVSIMEGCSKYC
                     TFCVVPYTRGDEVSRPLEDVLAEIAGLAAQGVKEVTLLGQNVNAWRGELVREDGEQGD
                     FAFLLECVAEIPGIERIRYTTSHPREMTQRLIDCYARIPKLVSQLHLPVQSGSDRVLA
                     AMKRGYSVLEFKSVVRKLRAARPDLSLTSDFIVGFPGETEDDFEKTMKLIEDIGFDGS
                     FSFVYSSRPGTPAADLEDPVPQETKLAWLARLQKRIDAQYQANSEAMVGTVQRILVEG
                     AAKKHPEVEMMGRSDNNRVVNFPSDSPHRDRLVGQFVEVRITAALPHSLRGEILTRES
                     "
     gene            complement(38170..38646)
                     /locus_tag="P5537_04640"
     CDS             complement(38170..38646)
                     /locus_tag="P5537_04640"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77366.1"
                     /translation="MASASRGGLLQSVERLIYKAFALTSPGRWTIIPGLFPNVPDLSG
                     PSLRPHFLSVLVAGLSGLASTLVFAALPRPIPDDAARVKMAFPSPGVVQVKDATLRLS
                     PGAQIRDTHNRIVLPSHVAGEYVVRMLMDRNGQVHRVWILTPEEAAAPMPKARSRP"
     gene            38821..38897
                     /locus_tag="P5537_04645"
     tRNA            38821..38897
                     /locus_tag="P5537_04645"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:38855..38857,aa:Met,seq:cat)
     gene            39255..41063
                     /locus_tag="P5537_04650"
     CDS             39255..41063
                     /locus_tag="P5537_04650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HRV77367.1"
                     /translation="MSSTHAATLPKQPHRRPPHRDGGRRFLLLAGGYWNCERKWQVRA
                     TVLALILLTMAQVGLAIWVSYWNRDLFDALEDRALSELLQLVGVFVLIFALTMGVTAL
                     HMHVKRRLQLDWRRWLTDLLLEHWLAHGHLYRLQFTAGEHDNPDGRIAEDIRIATDVA
                     VSLAHSLLFALLILGSFIDILLSVSGSAPLPGTSIAVHGYMVLAAFLYAGVGTALGLM
                     LGRPLIRATNRLQTVEANLRFGLARAREHAEPIAMMHGEPHERREAARLFDDVGRGWN
                     RQTLAYLGIVSFSTGYGTLLPVFPILIAAPQYIAGAMTLGVLMQAAQAFQRLTTALSW
                     PIDNLGELARCRASIDRVASLYEDMLALERAEARSRGRERIAVCASPHPELELRRLRL
                     QTPAGELLLDDFDLRVRRGERVLICGDPAVTISLFKAVAGLWPWGSGEVRLPAGRDLM
                     FVPRQPFLPAGGLRMVLSYPDDADRHPDAVLERALECAGIAWLAPKLDTQEDWGRELP
                     LRIQQRLGLARVFLHQPAWIFIEEATDALAPKEEVDSLELLHHELPSSTLLVISRRAR
                     QNHFFERRLLLQRPRTGVQPPAAHTARPEAPSLPEA"
     gene            complement(41049..42155)
                     /locus_tag="P5537_04655"
     CDS             complement(41049..42155)
                     /locus_tag="P5537_04655"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0071704 - organic substance metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="HRV77368.1"
                     /translation="METTRTKLRGVNLGSWLLLEKWMVPSLFEGLEATDETTWCAELG
                     PAATERLRRHWDSFVTREDFAWIAARGLNAVRIPIGHWIFGPDYPYHPKYGAHRHPFV
                     TGGIEVLDRALDWARELGLAVIIDLHAAPGCQNGFDNGGIKDVVEWHTRKEYLEHSLS
                     VLERLAERYHAHPALHGIELLNEPRWDVPTDYLKAYYLEAYARIRKHCAPEKVAVVFH
                     DGFRSFREYLGFMQAPAFRNVVFDYHRYQCFERCDIDMDIHGHIRKAAVDWREEADAI
                     NAELGLPAVCGEWSLGLDLKVVSLWAEGPFNHALEHMDDFQQDVASRAYGDSQLMTFE
                     RLAGWFFWSYKTETTPAWCFRECVERGWLPSRFG"
     gene            42392..43408
                     /locus_tag="P5537_04660"
     CDS             42392..43408
                     /locus_tag="P5537_04660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HRV77369.1"
                     /translation="MRTVEHVVTHLIVHALVREPGTPSRLVLREAPCALDAAALRLAE
                     RLCAQYESRNAKGFGRFEDDEESYPLARWLREHQVDETLDFTTLSRQLAERVQAIADE
                     EELEDGGHLVLARIREGDGDSLWVALLGSAEGVAIGGSLEPLDCTHVDFSALHAAGRV
                     DLAGWRRGDERYLGFLRGRGKGGAWFKRVLGCSDVMVALQETKKLVATLDRFVDTERL
                     APATRDAVLERAHDYLDTLGEAGAPVVFEELAREVFPEQPERLDALLKAEETRIAPGF
                     VPNRRAIRPLVRFSASAENWKLEFERSGLHSGAVHYDRATDTLVLSGVPDYLKRMLDE
                     EDKG"
BASE COUNT         6627 a        15736 c        14910 g         6137 t
ORIGIN      
        1 tggtagatag agcgaccacc gagataggcg atctcggcga cctcggcggc cgcgacgttc
       61 tctccaggat gttccgccac gcacgcatca ccggcggcgc gacgatgcac gcgcacgcac
      121 tcggggcgca gcgacagcca ggcttcgccg cccgatggcg gcgaggcgcc cgcgcccgcc
      181 gcgaagacga tcggctgcgg aaaatcactg cttgccaggc gatcgccctc gatacggccg
      241 tggaagagat tggtctcgcc gatgaagccc gcactgaaac ggcagttggg gcgctcgtag
      301 atctcgccag gggttcccac ctgcaccagc ccgccctcgg acaggatgcc gatgcggtcg
      361 gccatggtca tcgcctcctc ctggtcgtgg gtgacgagga tgcaggtgac gcccactcgc
      421 cggatgaggc cgacgagctc gaactgggtc tgctggcgga tgcgcttgtc gagcgcggcg
      481 aggggctcgt cgagcagcag caggcgtggc tcgcgcgcca ggctgcgtgc cagcgccaca
      541 cgctgctgct gcccgccgga gagctcctgc ggccgccgtc gggcgaaggc gcgcatctgc
      601 accagctcga gcatctcgtc cacgcgggcc gcgatcgccg cgcgcgccat gcgcgggcgc
      661 agctggcgca ggccgaaggc gacgttgtcc gccaccgtca tgtggggaaa cagcgcgtag
      721 gactgaaaca tcatgttggt cgggcggcgg tgcgccggca ccgcggcggg gtcctcgccg
      781 tcgagcagga tgcgcccgct actcggcgtc tccaggccgg cgatcatgcg cagcagggtg
      841 gacttgccgc agcccgagct gccgagcagc gcgaagatct cgcgctcgcc gatgtcgagc
      901 gagacctcgc gcaccgccca ggcgtcgccg aagcgcttcc ccaggcgctc gatgcgcagg
      961 tggacgggcg cgccggccaa gccttcggat gccccctgcg gcacacgctc gctcatcgcc
     1021 ccgcccgcct cgcgcgcgcc gcccttcagc gtgccgcctt gaagcggttc agcgcctggg
     1081 tcagctcgcg ctgcacgtcc ttgcccagca caggcttggc gcgcagcgtg cgcttgaccg
     1141 cctccggcac gttgatcacc gggtcgtcgc gcagcgtggc gtcggtgagc gcgagcgccg
     1201 cggtgttggc gctgatgtag aaggtctcgt tggagatgcg cgccaccgtg gccggatcca
     1261 tcatcgcgtc gatccagcgg tgggcgttgt gcggatgcgg cgcgtcgcgc gggatcgcca
     1321 tcacatccac cgacatcatc gcgcccacgg acgggatcag gtactgcagc ctgatctcgg
     1381 cgccggcgag ctgcgcgcgc cgcgcagcgg tgcgggcatc gccggagaac atcatcgcca
     1441 cgcacaggct gcccttggcc atctgctcga tcggcgcggt gttgaagctg cggatgtgct
     1501 tgcgcaccgg acggatgtgc tcgaccgcag cgcggatgtc ggcggggtcc atcctcaccg
     1561 ggtcgaggcc ggcgtcgagc atggccgccg ggatcacgtc gctggcctcg tccatcagcg
     1621 cgatgccgca gcccttcagg cgcgcggtga gcgcgggatc gaagagcagg tcccaggcgt
     1681 tctcgggcag cctgccgtcg agcgccttca tgaccttgtc gacgttgatc gcgaccccgg
     1741 tggtgaacca catgtagggc acgaggtggc gattgcccgg gtcggcgacc gccaccgcct
     1801 cgaggatcag cgggtcgata tggacgagat tgggcaggcg cgacttgtcg agcggctgga
     1861 agatgccggc ctggatctgc ttgccggcgt actccacgct cggatacacc acgtcgtagc
     1921 cgctgccgcc ggtcagcagc ttgccctgca gggtggcgtt gctgtcgtag aggtcgtagc
     1981 gcacatcgat cccgctcgcc ttctcgaagg cagggacggt gtcggcggcg atgtagtcgt
     2041 tccagttgta gacgttgagg atgggctcct ccgccgccac cgccaccccg gcggccaggg
     2101 ccagcgccgc catccagccg aacttcagct tcatgcccgc ctccccgcga tcgacaaggg
     2161 aacaccgcca gcccgccccg gccgagagac ccgggcgggg tacgctcaaa ccttcagccg
     2221 catctccgcc gagcgcgcgt gcgcctgcag gccctcaccg tgcgccagga tggacgccac
     2281 cttgcccagg tgctgcgcgc cggcctgcga gatgttcacg atgctggtgc gcttctggaa
     2341 atcgtaggtg ccgagcggcg acgagaaacg cgcgctgcgc atggtcggca gcacgtggtt
     2401 ggggccggcg cagtagtcgc cgagcgcctc caccgcccag tggccgacga agatcgcgcc
     2461 ggcgtggcgg atgtgggcga tccaggcctc ggcatcgtcc agcgacagct ccaggtgctc
     2521 gggcgcgatg cggttggcga gcgcgcaggc ctgctccagg ctgtcgacgt ggatcagcgc
     2581 gccgcggttg gcgagcgacc tggcgatcgt gtcgcggcgc ggcatggtag gcagcaggcg
     2641 gtcgatcgcc tcgtgcaccg cgtcgatgaa ggccgtgtcg gtgcacaaca ggatggactg
     2701 cgcgagctcg tcgtgctcgg cctgggcgaa gaggtccatc gccacccagt cggcgtggcc
     2761 ggagccgtcg gagatgatca gcacctcgga gggcccggcg accatgtcga tgccgacggt
     2821 gccgaacacg cggcgcttgg cctcggccac ataggcgttg cccggaccga cgatcttgtc
     2881 cacctgcggg atggtctgcg tgccgtaggc gagcgccgcc accgcctgcg cgccgccgat
     2941 ggtgaacacg cggtccacgc cggtgatcgc cgcggcggcc agcacgagcg ggttcttctc
     3001 gccgcgcggc gtgggcacca ccatgatgag ctcgccgacg ccggcaacct tggccgggat
     3061 cgcgttcatc agcaccgagc tcgggtagga cgcgcgcccg cccggcacgt agaggccgac
     3121 gcggtcgagc ggcgtgacct tctgccccag gcgggtgccg tcggcctcgg tgaactccca
     3181 ggactcgccc ttctggcgct cgtgatacac gcgcacgcgg tcggcggcga tggtcagcgc
     3241 ctcgcgctgc tcggggcgca ggctgtcgag cgcaagctgc agctcgctct tcggcagctc
     3301 gagcgccacc atggattgaa cgtcgagccc gtcgaagcgg cgggtgtatt cgaccaccgc
     3361 ggcgtcgccc gtggtgcgaa ccgcctgcag gatctcggtc accgcggcgt cgatgcggcc
     3421 gtcggactcg gcctcgaagg cgagcagggc gtcgagcgtg gacaggaatt cgggttcgcg
     3481 cgcgtcgagg cggcggatcg gcgtctggct catgaacggg tccttagggt tggatcgcgc
     3541 cggcgaacgc gtcgagcacc ggctgcagca gttcgcgctt gagcttgagc gaggcctggt
     3601 tgacgatcag gcgcgagctg atcggcatga tgtcctcgac ctcttccagg ttgttggcgc
     3661 gcagggtgcc gccggtggac accaggtcga cgatcgcgtc tgccagcccg accagggggg
     3721 cgagttccat cgagccgtag agcttgatga ggtccacatg catgcccttg ccggcgaagt
     3781 gcgccttggc cgcgttcatg tacttggtgg cgacgcggat gcgcccgccc gggcgcgtgg
     3841 cagcggcgta gtcgaagccc ttctgcaccg cgacacacag gcggcacttg gcgatgttca
     3901 ggtcgagcgg ctggtagagg cccgcgccgc cgtgctcgac cagcacgtcc ttgccggcga
     3961 tgccgaggtc ggcggcgcca tactgcacat aggtgggcgt atcggtggcg cgcacgatca
     4021 ccaggcgcac atccgggcgg ttggtgccga tgatcagctt gcgcgacgac tcggggttgt
     4081 cggtgggcac gatgcccgcg gcggcgagca gcggcagggt ctcttcgaag atgcggccct
     4141 tggacagggc gagcgtgatg ctggacacgt gaaaagcctt gatcgggggg accgcgcatt
     4201 gtaacccggc gccgcttctg ttaaccttcg tcgcgactgg ctgaaccgcc cgcggtggtt
     4261 cggccttttc ttttgttccg ccgcgccacg ggcgcgtgca ccgcgcagga ctttcccagc
     4321 atgaaaccgt cgatcatcgt ctccagcagc gacctcgagc gcctcgaggg tctgctcacc
     4381 ctccccgcct tccgcagccg cagcgatctc gacggcctgc gcgaggagct cgagcgcgcc
     4441 gacgtgcgcg agccacagga catgccggcc gacgtgatca cgatgaacag ccgcgcgcgc
     4501 ttcgtcgagg aaggcaccgg gcgcgagtac gagctgaccc tggcctaccc gaaggacgcc
     4561 aacgccgagg cgcatcgcgt gtcgatcttc tcgcccgcgg gcagcgcgct gcttggcctc
     4621 tcggccggcc agtcgatcga ctggaaatcg tccgacggca aggagatccg cctgagggtg
     4681 ctggaagtca cctggcagcc cgaagccaac ggccagttcg agctgtagga gcaccggcag
     4741 gcgagagcac ggcgaccgga catgaccggc gcgccggggg gccggacggc tgcattcgcg
     4801 gctgccgccg ctcctacatg ggcgccgtgc cggctcccgg agcaggaggg gtggcagccg
     4861 cgaacacggc gacacgggcg ccgcgcgggc tcaccgtgca ggagcggcgg cagccgcgaa
     4921 cacggcgcgc cgacggtcgc tgtcgcgcgg ccgcggaagg acgcaccggg cccccgaccc
     4981 ggaacgtccc gcctccctgc cccgcctcag gcgaggcgcc gcaccttcgc gccgagcgcg
     5041 gccagtttct cttccaggcg ctcgtagccg cggtcgaggt ggtagatgcg ctcgatcgtg
     5101 gtctccccct cggccaccag ccccgccaca accaacgatg ccgaggcgcg caggtcggtc
     5161 gccatcacga tcgcgccctg cagtgtgtcc accccctgca ccaccgcggt gttgccgtcg
     5221 atgcggatgt cggcaccgag gcgctgcagc tcgaccgcgt gcatgaagcg gttctcgaag
     5281 atggtctcgc ggatcatcgc cacgcccttg gcgaccgcgt tgatcgccat gaactgcgcc
     5341 tgcatgtcgg tcgggaaggc cggatagggc gcggtgcgca ggctcacggc gttcaggcgc
     5401 gccggcgcgc tcaggcggat cgcatcgcgc tcggacacca cctcgcagcc ggcgtccatc
     5461 agcttgtcga tgaccgcgtc gagataacac gaggaagtgc cggtgagccg caccgaacca
     5521 ccggtgaccg ccgccgcgca caggtaggtg ccggtctcga tgcggtcggg catgatgcga
     5581 tgggtggcgc cgtgcaggcg ctcgacgccg cggatgcgga tcacgtcgct gcccgcgccg
     5641 gagatctgcg cgcccatcgc caccaggcag ttggccaggt cgaccacctc gggctcgcgc
     5701 gcggcgttct cgatcaccgt ctcgccgtcg gccagcgccg ccgccatcat caggttctcg
     5761 gtgccggtaa cggtcaccat gtcggtgaac agccgagccc ccttcaggcg cggcacggtc
     5821 gcatgcacgt agccgtgttc gacgcgcacc tccgcaccca tggcctgcag gcccttgatg
     5881 tgctgatcca ccggccgcgc accgatcgcg cagccgccgg gcagggacac ccgcgcctcg
     5941 ccgcagcgcg ccaccagcgg gccgagcacg aggatggagg cgcgcatggt cttgaccatc
     6001 tcgtagggcg cgaccgggtt gtcgagcgcg gaggcgtcga gcgtcaccac gtcggcctcg
     6061 cgcttgacgc gcacccccat ctggccgagc agcgccagca gggtgtcgat gtcgttgagg
     6121 caagggacgt tggtgaaggt gaccggctcg gcgctcaaca gcgcggcgca gaggatgggg
     6181 agggcggcgt tcttcgcgcc tgagatggcg atctcgccgg acaggcgggc accgccttcg
     6241 atcagaagct tgtccatgcg caactcacat cccgagttcg ccgcgacctt cttcccactg
     6301 tgcgggggtg aaggtctgca gctgcagggc gtggatctcg ttgcccatga ggcggcccag
     6361 ggtggcgtac accgcctggt gctggcgcac cttcatcttg ccctcgaagg cggcactgac
     6421 cacaatgccg cggaaatgca cgccatcctc gccctcgatg accaccagct cgcagggcag
     6481 gccctgctcg atcaggcgct tgacttcgct tgcttcaaac atttggaatc ctttacgaac
     6541 gcaacttgta accgcgcgcg agcatcgcca gggtgagcgc cgcgagcagg acgaaacaca
     6601 ggcccacgac gccgagcgac agccacggcg aggtgtccga ttgaccgaag aaaccgtagc
     6661 ggaacccgtc gatcatgaaa aagaacgggt tgaaatgcga cacgtcctgc cagaactgcg
     6721 gcagcgagtg gatggagtag aacacgcccg acagcatcgt cagcggcatg atgaggaagt
     6781 tctggaaggc ggcgagctgg tcgaacttgt ccgcccagat cccggcgatc accccgagcg
     6841 agccgaggat cgcgccgccg agcacggcga agcccagcac ccacagcggg tgcgccatcg
     6901 gcacctcgac gaaggcggcc gacaccgcga gcacgcccgc gcccaccatc agcccgcgca
     6961 gggtcgaggc gatgacgtag gccgcataga actcgcggta ggacagcggc ggcagcagca
     7021 cgaagatgat gttgccggtg atcttgctct ggatgagcga ggacgagctg ttggcgaagg
     7081 cgttctgcag caccgacatc atcaccagcc cgggcaccag gaagctggtg taggcgacct
     7141 cgccgtagac cgtgacgtgg cggtcgagca cgtgcgagaa gatgagcagg aacagcagcg
     7201 cgttgagcac cggcgcgcca acggtctgga agctgacctt ccagaagcgc agcacctcct
     7261 tgtacagcag cgtgcggaag ccggcgagcg gcgactcggc cgccatcggc tcgatgcgcg
     7321 ggacggcgcg ggagaaggat tcaggcacgg ttcatcacct cgacgaagac gcgttcgaga
     7381 tcgggctcgc cgagccgcat ctcgacgagg cccgcgccag cctcgcgcag gcgggcgagc
     7441 agggcctcga cctcggtgta gctgtcgaag gcgaagtcca cccagccacc ctcgccggcg
     7501 ctgccgccga gctcgacgcc gcgcccggga tgctcgaggc gcacggccag gctgtgggtg
     7561 gcgaagcggc gcagtaggtt ggcggtggtg tcgagcgcga cgatgcgccc ggccttgagc
     7621 atcgcgatgc gtccgcacaa ggcctcggcc tcttccaggt agtgcgtggt gagcacgatg
     7681 gtgtggccgt cgcggttgag cttgcggatg aactgccaca ggccctggcg cagttccacg
     7741 tccacgcccg cggtgggctc gtcgagcacg atcaccggcg gccggtgcac cagcgcctgc
     7801 gccaccagca cgcgccgctt catgccgccg gagagcatgc gcatgttggc gttggccttg
     7861 tgcgcgaggt cgaggctggc gaggatctcg tcgatccagt cgtcgttgct gcggatgccg
     7921 aagtagccgg actggatgcg cagcagctcg cgcaccgaga agaatggatc gaagacgagc
     7981 tcctgcggca ccacgccgag gttgcgccgc gcattgcggt agtcggcgac gacgtcgtgg
     8041 cccatgatcg ccagcgtgcc gccgtcggga cgcaccaggc cggagagcgc cgagatcagc
     8101 gtggtcttgc ctgcgccgtt ggggccgagc aggccgaaga actcgccctg gccgacctcg
     8161 aggtcgacac cgccgagcgc cttcaggctg ccgtagtgct tgcttacacc ctggatgcgg
     8221 atcgccggcg tgctcatgca gcgcgctcca gcggcagcag gccgtcgatg tcgtagagcg
     8281 cggcgaggct ggccagcccg gcgggcgggt tgcgcagcac cagcgcgtgg ccggccgcgc
     8341 gcgcgcagcg catccagtcg agaatcaacg cgagcgcggc ggaatcggcg gcggacaccg
     8401 cggcgagatc gaccaccagg tcgcccgcgc gcgcgcgccg ctggccctcg gcgagcagcg
     8461 ccggcgcgcg ctgcatggtc agcgcgccct cgggcgcgaa cacggcggga tcactcacgc
     8521 gccgcgcccc gcgccagcct ggctcatgcc ctgctgctcg gcgagcgcgc ggttgcgctc
     8581 ctcgagcgag cggatcaggc cgtcgatgcc gccgcgcgcg atctcctggc cgaagctgct
     8641 gcgatagttg gtgaccaggc tgacgccggc gacgatcacg tcgaacacct tccagccctg
     8701 ctcgctcttc tcgagcatgt agtcgatgcc gatcggctgc gcaccggcct gaaccacctc
     8761 ggtgcggatc tgcacgcggg tgtcggcggg cgcgaagcgc gaggggcgga actcgatgcg
     8821 ctggtcgcgg tactgggtca gcgcgttgga gtaggtgcgc accagcaggg tacggaaggc
     8881 gtcggtcagc ctgccctgct gctcggcgct ggcctggcgc cagtcgcgcc cgaccgcgag
     8941 catggtcatg cggcggaagt cgaagtgcgg cagcaccttg gcgtcgacca gctcgatcac
     9001 gcggcgggtg tcgccggcct ggatcgccgt gtcggcgcgc acgatctcga gcacttcgtt
     9061 ggtcacgtcg cgcaccagca ggtcgggcgc cttgtcggcg ctggcagctg cgggcagcgc
     9121 ggcaccgaac aacgcacaga ggaggaagac gcggagaaaa tcgaggatct tgttcatggc
     9181 tctcgtttac tggatggttt ggcgggtgac gcggcgcccg gtcgtggccg gggtcgcgcc
     9241 gatgcccgcg agctcgaggt tctcgaccgc ggtggcggcg gccgcatcga cctcgccccc
     9301 gagcggcgcg gccgactgtt cgtcgaaatc ttcatacacg cgttcctggc ggccatcgct
     9361 gaccttgtaa cggcgttgtt cgaggtagaa gtcgcgcacg aaggcgtagc ggtcgagcgc
     9421 cgcctcctcg agggtacggt cggcgccgag cagcaccgaa cggccgtgca cgacccgcgt
     9481 gcccagcacc gtgttgcgcg tcggcacgtg atcgatgctg aaaggctcgt tacccatcat
     9541 gtcggcgggc agggccaccg cgtcgcgcac cgtgcgcgga ccgaagaagg gcagcacgat
     9601 gtaggcgccc tcgcccacgc cccagcgccc cagcgtctgc ccgaggtcct cgtcgtgctt
     9661 gggcaggccg gcctcgctgg cgatgtcgag caggccgagc aggccccagg tggagttgag
     9721 cgcgaagcgc atgaggtcgc tcatgccctc ggcgaccttg ccctgcaaca cgttgttgag
     9781 cgcgatccag gggtcaccga ggttgccgag cacgttgccg acaccggtgc gtaacgggct
     9841 cggcagcacg gcctcgtaca cctgcgcggc cggcttgatg gcgaccttgt cgagctgctc
     9901 gttgaagctg aacatggccc ggttgtaacc ctcgagcggg tcgtcggggt tgccggtggt
     9961 ggcacagccg ccgagcagcg cggccgagat cgcggctgcg gcgaggctgg cgcgggagga
    10021 gcggaagacg tttcgcattg ttttttctcc ggggatcctg gccgacttac tgggcgggcg
    10081 cgtcggcggc gcggtcgaac atgaactggc cgatcagctt ctcgagcacc accgcggact
    10141 gcgtgatcag cacgcggtcg ccgttcttca gcatctcgcc gtcggcgccg gcctccagcc
    10201 ccacgtactg ctcgccgagc aggccggagg tgaggatgga ggcggtggta tcggcgggga
    10261 aggcatagcg cttgtcgatc tcgagttcga ccacggcacg gtagatcgcg ggatcgaagc
    10321 ggatcaccgc gacccggccc acgagcacgc cggagctctt gaccggcgcg cgcaccttga
    10381 gcccgccgat gttgtcgaag ggcgcctcga cgcgataggt ctcgctgcca tccagacccg
    10441 agaaattgcc gaccttcatc gccaggaaca ccagcgcggc gaaaccgatc gcaacaaaaa
    10501 tgccgaccca caggtcgagc gcggtacgac tcatcatcaa cccctgaaca tgaaggaggt
    10561 aagcacgaaa tccagcgcca ggatcgccag cgcggaggtc acgacggtgc gggtgatcgc
    10621 gcgcgacacg ccttcggcgg tcggctggca atcgtagccc tcgaacaccg cgatcagcga
    10681 caccacggtg ccgaacaccg cggacttgat cacgccgttg acgacgtcgt agcggaattc
    10741 caccgcggcc tgcatctgcg accagaacgc gccgtcatcg acgccgatca caaccacggt
    10801 gatcagccag ccgccgaaga tgcccatcgc cgagaacagc gcggccagca gcggcatcga
    10861 cagcacgccg ccccagaagc gcggcgcgac cacgcgcgcg atcgggttga ccgccatcat
    10921 gtccatcgcc ttcaactgct cggtggtctt catcaggccg atctcggcgg tgatcgcgga
    10981 gcctgctcgg ctggcgaaca gcagcgccgc gatcaccggg ccgagctcgc gcagcagcga
    11041 cagcgccacc atcaccccca ccgcgtcggc cgaaccgtag cgctgcagga tgtcgtagcc
    11101 ctgcaggccg agcacgagac cgacgaagag ccccgagacc atgatgatca gcagcgacag
    11161 cacgccgctg aaatagagct cgcggatggt gagatggatg cggcgcagcg actgcccgga
    11221 gttcagcagc accgcaagca ggaagcgggt ggcgaagccg agccgccaca cgccgtcgat
    11281 ggtcagcgcg ccgatgcggc gcagcgcgga ggcgatggcg ttcatgcgct ctccccgccg
    11341 agcaggcggt cgatcggctc ggccggatag tggaagggca ccggcccgtc ggcctcggcg
    11401 tggacgaact gatgcacgaa gggatccctg gaggcgcgga tctcgtccgg cgtgccctgt
    11461 gcaacgatgc ggccgtcgga gacgaagtag atgtagtcga cgatcgccag cgactcgtgc
    11521 acgtcgtggg tcaccatcac cgagctcgcg ccgagcgcat cgttgagctt gcggatgagc
    11581 tggccgatga tgccgagcga gatcggatcg aggccggcga agggctcgtc gtagaggatc
    11641 agcatggggt cgagcgccac cgcgcgcgcc agcgccaccc gccgcgccat gccgccggag
    11701 agctcgttcg gatgcagctt cgccgcaccg cgcagcccca ccgcctgcag cttcatcagc
    11761 accaggtcgc gcaccatgcc cacgggcagc tcggtgtgct cgcgcagcgg gaaggccacg
    11821 ttgtcgaaca cgctcatgtc ggtgaacagc gcgccgaact ggaacagcat gcccatgcgt
    11881 cggcgcagcg catagagctc ggcgcccgaa agccgcgcca cgtcgcgccc ctcgacctcc
    11941 accgtgccgg cggtcgcgcg cagctgcccg ccgatcaggc gcagcaaggt ggtcttcccg
    12001 caaccgctgc cgcccatgat ggcgaccacc tggccacgat gcacgctcag gtcgatgccg
    12061 cgcagcacct cgcgctcgcc ataggcgaag cgcacgtcgc gcagcgaaac cagcggggag
    12121 ggatgtgggg cggacacgct cacgtcgatc ggccgaatgt gaaaactctt gaatatatca
    12181 gagatttgca cctgcagccc ggaaaatgct gcagcgcaac aacctgattc gggcgatcgc
    12241 ctgctccacg cgctcccgtc cctcgctgcg ggggccaccc aacagaaaaa tggattcgat
    12301 tattcacatt tcgattttat cgtaatagca ttgttacatg acattccaat tgcacggact
    12361 gcacaggctg atcacggccg cgacgcttct ggcgaccgcg ggatgcgtgc cgctgacccg
    12421 tccgcccgca ctcgaaggcc atctcgacca acgcaccgcc atcgaccgac cggagcacac
    12481 ccgcagcacg gcacggcccc acgcaccgac atccacggcg gcctctccgg ctggcccgag
    12541 cgctgcaccg caagaccgga cgatccagcc gccccccacc cggcagcacg gccgcccgga
    12601 gcgcgggtat tcggtcgacg tctacgacat tcccgccgag cagttgctgc tcgccatcgg
    12661 ccgcgacgcc gggctggagc tcgaccttca cgcggggatc accggcaagg tcagcctgca
    12721 ggcccatgac cgcccgctcg gagagctcct cgaacgcatc gcccgccagg tcgacctgcg
    12781 ctacgagctg cgcggccgcc acctgcgcgt gcgccccgac acccccttca tccgcagtta
    12841 cgcggtggac tacgtcaact tgagccggga catgcgcggc acggtcgcca ccagcacgca
    12901 gatcgccacc tccggcagcg gcggagctgg ccagcgcacg tcgtcggcag gcggcgccgg
    12961 caacgcctcg atcacccaga tcgagacgcg cgcggccaac gacttctgga acacgctcga
    13021 gcacaacctc gcctccatcc tcgccgggcc ggggcgtgcg cccgattgcg gcggcgagcg
    13081 tgcgagcgag cgcgccggag gctgccgcaa cgccgacctg atgctcaacc gcgagagcgg
    13141 catcgtcatg gcgcgcgcca cagcacgcca gcacgagcag ctcgaggcct tcctcgccgg
    13201 cgtgcagcgc gcggcgcgcc gccaggtgat gatcgaggcc acgatcgtcg aggtcaccct
    13261 ggccgacggc taccgccagg gcatcgactg gacccgactc ggcgtgccgg gctggagcgt
    13321 gcgtccgcgc ggcagcggcg acgccacacc cggccagccc acgctgagct acctgtcggc
    13381 caactccgac atccgccttg agctgctgga gaccttcggc accgtcaagg tgctctccag
    13441 ccctcgcctt tcggtgctca acaaccagac cgcgatgctc aaggtggtcg aggaggtcgt
    13501 gtatttcctc gtcgacagca ccaccaccga atacgacgac cgcaagcagg cgcgcatctc
    13561 cgcgaccacg acgccacagt cggtctcggt cggcatggtg atgtcggtca ccccgcagat
    13621 ctcggccgat ggcgacatca ccctcaacgt gcggccgacc atctcgggca tctccggctt
    13681 caaggacgac cccaacccct cgctcggcga catccccaac cgcgtgccgc agatccgcac
    13741 gcgcgagatc gagtccatgc tgcgcctgcg cagcggcgag gtcgccgtgc tcggcgggct
    13801 gatggaggac cgcctcgacc acgacaccgg ccgcatcccg ctgctcggcg acctgccggt
    13861 ggtcggcgag ctgttcaccc ggcgcgacaa caacgtacgc cgcaccgagc tgctgatctt
    13921 cctgcgcccg ctgctgatcg acgagccggg catgcgcggc ggctatgccg aatacgccgg
    13981 ccgcctgccc gacgacgact tcctcctcga ctcgccctcg cccggccagc gcaattttcc
    14041 ccacctgccg ctgcgtcccc tgctcgcccc ggcagggacc gctccggtcg ccgacgggct
    14101 ctccgacgca gcctatcccg acgctgccgt cctccactcc tccgatcccc gcccttccca
    14161 cccatcctcc ccgtccgccc gctccgcccg ggcggctgcc gccacgagcc cgccatgaac
    14221 gctcctctcc ccatcggcca gaccctgatc gccgccggcc tgatcggcga ggaccagctc
    14281 cgcatcgccc tgcacgagca gcgcgggcgg tcccagccgc ttggccgggt gctggtggaa
    14341 ctcggtttcg tcagcgaggc cgcgctgcgc gaggcgctcg ccgcgcgcag cggcctgccc
    14401 tgcgtggacc tcgccacggc cctcgccgac cccgatgcga tcgcgcgcgt gccgcaggcg
    14461 ctcgcccgcc gccaccgcct gctgccgctg cagtacgacg ccgcccgcca tcgtctcatc
    14521 gtcgcgatgg ccgacgccca cgacatcgtc gccctcgacc gcctgcgcgc cgagctcggc
    14581 ccggatgtac acgtcgagct gcgcctggcc ggcgacagcg agctcggccg cgcgatcgag
    14641 cagcactacg gccaggcgag ctcgatcgag gacatggtgc gcgagctcga acgccgcgcc
    14701 ggccagcccg tcaccggtgc gcgcgacccg cagctggtcg tgcgcctggt ggacgcactg
    14761 ctcgccgagg ccgccgcgcg cgctgcctcc gacctgcacc tggagcccga ggcgggcttc
    14821 ctgcgcgtgc gccaccgcat cgacggcacg ctgcgccagg tgcgcgcaat gcacaagtcg
    14881 tgctggccgg agctcgcggt gcgcatcaag gtgctcgccg gcatggacat cgccgaatcg
    14941 cgcagcccgc aggacggacg catcgggctc gcggtcggcg ggcgacccat cgactttcgc
    15001 gtcgccaccc agcccaccct gcacggcgag aacatcgtgc tgcgcatcct cgaccgcgac
    15061 aagggcatcg tcccgctcga cgcgctcggc ctcgaccccg cgcagagctc cgcgctccac
    15121 cgcatcctcg cccgcccgga gggcctgatc ctggtggtcg gccccaccgg cagcggcaag
    15181 accaccacgc tgtactcgat gctcggccac ctcaacaccg aggcggtcaa catcatgacc
    15241 ctggaggatc cggtcgagta tccgctcgcg ctgatccgcc agacccaggt cggcgaggcc
    15301 tcccggctcg acttcgccga cggcgtgcgc gcgctgctgc gccaggaccc cgacgtgatc
    15361 ctgatcggcg agatccgcga cgccgacacc gccacgatgg ccttgcgcgc ggcgctcacc
    15421 ggccaccagg tgttcgccac cctgcacgcc aactccatct tcggcgcgct gccgcggctg
    15481 cacgagatcg gcatcggccc cgagctgctc gccggcaacc tgtgcggcat cctcgcccag
    15541 cgcctggtgc gccggctgtg cgccgcctgc cgcgagccgg tcccggacga cgcccccgag
    15601 cgccgcctgc ccggcctcgc cgacgctgca ccgccaccgc cgagctggcg cgcgcgcggc
    15661 tgccccgagt gcgacttccg cggctaccgc ggccgcctcg cgatcatgga gatcctgccc
    15721 ttcgacgccg ccctcgacga gctcgtcgcg cgccgcgcca gcccgggcga gctgcgcgcc
    15781 gcagcacgcg cctgcggcca ccgcagcctg gccgaggacg gcctgcgccg cgtgctcgac
    15841 ggcagcacca gcctcgccga actcgcccgc gtggtcgacc tgtccgcgct cgcagcgatg
    15901 cccgcagccg acgtcgcgca agggggcatc gcatgagcag ctggcgctac cgcgcgctcg
    15961 ccgccgatgg ccgccgcgtg cgcggcgagc tcgatgcggc cgacctccgc gaactcgagc
    16021 gcatgctcga ggcacgcgcc ctgctgctgc tcgacgcccg cccgcgcggc acgctcagcc
    16081 tgctgcagcg caggcgcatc ccgcgcagcg agctgatccc cttctgctac cacctcgagc
    16141 aactgctcgc cgccggcgtg ccgcccttcg agagcctcgc cgcgctgcgc gatgccggcg
    16201 ccgagccgcg gctgcagcag gtgatcgatg cgctcatcac cgacgtcgag cgcggactgc
    16261 cgctgtcggg cgccgccgcg cgccagcccg aggccttctc cgccgtcgcc gtcagcctgc
    16321 tgcgcgcggg cgagcaggcc ggccgcctcc ccgaggcgat ccgcgacatc ggcgccgcgc
    16381 tcgcgcagga ggaagagctc gccggccacg cgcgccgcat cgcgatctat ccgtccatcg
    16441 tcgccacggt gctgctggcc gcggtcgtgg tcgccctcgt ccacgtggtg cccgagctcg
    16501 agcgcctgct gcgcggcacg ggccagcgcc tgcccttgca gacgcgcatc ctgatggggc
    16561 tgtccggggc ggtgcgcgac tggggctggg cgatgctgct ctgcacgctc ggcggcacgg
    16621 cgctcggcgc gcacgcgctc gcccgctccg aacccctgcg cacccgcctg cacgccctgc
    16681 agctgcgcct gccgctggtc ggcgggatcc tgcgcaagct cgccctggcg cgcttcgccg
    16741 cgctcttcgc caccctgtac ggcgccggaa tcaatgtcat cgaggcgctg cacaccagca
    16801 ccggcgccac cgccaacctg gccctgcgcg ccggcctgcg cgaggccacc ggcgcgatcg
    16861 agcagggccg cccgatctcg gtcgccttcg aggcgacgca ggtcttcccg ccgctcgtca
    16921 tccgcatgct gcgcctgggc gaacacaccg gcgcgctcga cgacgcgctc accaaggtcg
    16981 ccagcctcta ccgccgcgac gtcgccgagg gcatcgcccg cctgcaggcc gcagccgaac
    17041 cggtgctcac catcctcatg ggcggcctgc tgctgtggat cgcgagtgcg atcctggggc
    17101 cgatctacga gctcatcacc cgcctgccgg tctgaccatg cgccgcgaac ccctgctcct
    17161 cgccgtggcc tcgtccggcc tgctcgcatg cagcgggcat gaagaaggta tccggctcct
    17221 tgccgccttc atgcctgggg acgaggccgc cttcgcgagc tggctcgcgc gtcgtgcgcc
    17281 ggacgagcca tgccgcgtgt tggtcgacct gcccgacgag gcctacgaga tcgaggacct
    17341 gccccgggtg cgcggcggcg accgccgcgc cctgttcgcg cgccgcctcg cgcactggtt
    17401 ccccgagccg cgcttcgcac gcgcatggtc gctcggcgcg ccttccgaag gacgcaaggg
    17461 cttcgagcgc gtgctgttct ccgggctcga gcgcagcgcc gagctgatgc cctggctcga
    17521 gcgcctggaa gccgacggcc gccggcccga gctcctcgcc cccgccgccg ccctgctgcc
    17581 gcgcctgccg ctgccaggcg cacgccagcg tcgccgcagc aaggggccct cgcgaccgcg
    17641 cctggtcgcc gccagcggac gcgcaggcct gcgcatcgcg ctgctggacc gcgaacacac
    17701 cctgttctcc cggctgttgc gcgcccacgc cgaaaccctg tccgatccgc aagcgctggc
    17761 gagcgagttc gagcgcaccc gcgactacct cgtcgcccag cacaggatcg cgagcgatac
    17821 gccgctcgat cgcatcgcgg tggaccttcc cgcccacccc ggggcggagc aggccacatt
    17881 ggctccggtc ggcatcgtcg ccgccgacac gctcgcggtc ggtacgccgc cgagcggcta
    17941 cgacgctcac ctgcttctcg ccctgcgccg cgcgcccgcg acgatcggct ggccgctcgc
    18001 caccctcgcg cggcgctggc ccggactggc cgggagacgg gtgttcgccg cgctcggaat
    18061 cgccgtcgcg atgctcctgg gcggcttcgt ctggatggac cgcctggcgc aggccgaggc
    18121 cgaagccctc gccgcggccg agcgcgcccg cgccgcgcgt accgccgcgc tcgcggccga
    18181 ggaggccgag cgcaccgcac gcgaggccga acgtgcagcg ctcgccgcac tcgacgtcgc
    18241 tccgcctgcc ccgctcccgc cgacagtggc cgcacccgag cccgaaccac ccgccatccc
    18301 cgtgccgacg cccgccacct gcccacctgc atccagcccg ccacccctgc ccatcccacg
    18361 gcgcatcgac ggcatcctgc gccgcccgga cggcgaggtc ctgctctggg tcgagggcag
    18421 ctggcaatcc gcacgctcgc tcggcctgcg cccgacggcc ggcgacgctg ccgcagtgtc
    18481 gccggcggga cggcgcacgc gactgcgcag cggggattcg ctgcccgtcg agctttcgac
    18541 acgggcgatc ggggcggtgc agcctcatcc cgagcaggac cagcccgcgc ccaccgcccg
    18601 cgaggggagt tccagcaccc accctgcgga gcacggctct ggcgctgcag ggtccgcgct
    18661 cgccgcaccg gaatcctccc tattgaccgc gaagcccgcc ctcgccgcca gtggagcgca
    18721 accatgaccg tcccgggcgg actgcgagcg ccgcagcgac acgaccgcct tccgcaggcg
    18781 atcgcaaagg ccttcgcgcc gaccggcgcc cggcgagacg tggccgcggc ccatggccag
    18841 gccctgatcg ccgccctcct gctgctcacc ctgctcgccg cgggagggct gctcgccggc
    18901 ggcgaactgc gcgcccgcgc ccacgcgctc gcccacgcgc gcagcgtcga ggcgctcgcc
    18961 atcgcccgcg ccgccctgat cggctacgcc atcagctacg ccgagaccca cccgggcgag
    19021 ggctacggct tcctgccctg ccccgacgcg gggaacaccg gctccacgcc ggtcggcgcc
    19081 tgcggcgcgc gcggcatcgc cgcggtgggg cgcctgccct ggcgcaccct gggcctgccc
    19141 gagctgcgcg acggctgggg cgaatgcctg tggtacgccg tcgccggcag cgtcaagcac
    19201 aaccctaagc cgcaggcgct caactgggac agccccggcc agttccgcct gctcgacccc
    19261 gcgggccgcg cgctcgaggt ggcggccgcc gacggcatgg cggtcgcggt cgtgttcagc
    19321 cccggcccac cgcgctccgg acagacccgc ccggcaagcc tgggaacgca ctgcactggc
    19381 agcgactcgg ctgcagccga tctggcccac tacctcgacc ctggccacgc acgcgcaggc
    19441 agcggaccga tcgagctcac cctccacccg gccacgctcg acgacgcggc gcccaacgac
    19501 ctcgccgcct ggatcggcat cgacgacctg ttcgacgcac tgcgtcggcg ccgtgaccac
    19561 gccggccatg tcgacgcgat cctcacgcgc agcgccaacg cgctcgccgg tcgtctcgcg
    19621 agcaaccgcg aggcctggct ctcgcgccac gcccgcagcg tcggcgcact cgcgaccggc
    19681 gtgctgcccg cagcggagac gctcggcatc gcggccgccc agcgtccgct catcgacgac
    19741 tggcgcgagc agatccgctt cgctgcctgc accgacggca gcgcctgcat cggcgtggtc
    19801 cggcccgcgg cgccgggcga gcgctgccgc gcagtgctcg ccttcggcgg cgagcgcact
    19861 cgcggcgacc cgggacgcca gatgcgaacc acgcctgccg agcgcgccga cccgtcagcc
    19921 tggttcgagg gccgcaacgt cgccgcactg cacctcggcg tgccggagtt cgagggtggc
    19981 gagcacttcc gcgtcaccga ccccgaccgc cccgccacgg aggacgtcgt ccgatgcctg
    20041 ccctgacccc ggccaccgat ccgatgcacc tgctcgcgcc agcaggccgc cgccctctgc
    20101 tgcagcggcc cggcgagccg gcacgccacg cccccgggca cagtcggtcc gcgccgggcc
    20161 gcgggatcgc gcgcggcttc accctggtcg agctcgccat ggtgctggtg atcctcgccc
    20221 tgctcggcgg cagcctgctc gtcccggtgg cgagccggct cgaggcgcgc gaccgcaacg
    20281 ccaccctgga gcgcctgcgc gacatccagc atgcgctcac cggcttcgcc atcatccacg
    20341 gccgcctgcc ctgcccgagc accgagaccg accccgccaa cccggcctac ggcctcgagg
    20401 acggcccacc gtgcaacctc gcgcgcgagg gcgtgctgcc ctggcgcagc ctggccatgc
    20461 ctgcgaccga cgcctggggc cgcgaccgcc acacggctgc cgacgactgg gcggggcact
    20521 ggcgctaccg cgtcgatccc gccttcagcg tggcgccgat cggcgcggcg accgccccca
    20581 gcgcccgcct gcagatccgc gaccacgacg gccgccgcat caccacgacc gactcgcagg
    20641 cggtcgcgat cgtgtggtcg accggcgcca acctgcgcgc cgacggcgac aacagcagcc
    20701 atgccagcgc caccccgagc taccaggctg gcgagccggg cgccgacttc gacgacctgc
    20761 tcgcctggat cggccgcccg ctgctgatcg cacgcctcgc ccaggccgga cggctctgaa
    20821 cccggccgtc aacgcccgcg ccagcaaagc cctttcacca ccgcaccacc aaccaggaga
    20881 acgaccatga ccagaaagcc gcaaaccgga ttcaccctcg tcgagatcgc gatcgtgctg
    20941 ctcgtggtcg gcctgctgct gggcggcgtc atgaagggcc aggcgctgat cgacagcgca
    21001 cgcgtcaaga acctcgccca ggacctgcgc agcgtgccgg cgatgatcca tgcctatcag
    21061 gaccgcttcc gcgccctgcc cggcgacgac cctgccgccg tccgccatct atgctccggc
    21121 ggcggtgcct gcaccgtcgc aggcaacggc aatggcgtga tcaacggtga ctgggatgcg
    21181 ggcgccgaca ccgaatcggt ccgcctgtgg cagcacctgc gccttgccgg cctcgccacc
    21241 ggcagcacgg acaccgccga cgccggcttc ctgccgcgca acgcgctcgg cggccgggtc
    21301 ggtgtgcagc gtggcggcag cgtgctcggc ctgccgggca gcttggtggt gtgttcggac
    21361 aacgtaccgg gcaagctggt gacgcagctc gacatcgcgc tcgacgacgg cgaccccgcc
    21421 gccggttcgc tgcgcgccgg ctcgcccggc gacagcgggc tggtagcgat ctctgccgcc
    21481 aacccactgc tcgaggcgaa cgcgcacacg gtgtgttcga atctgtgacg cgtgaggggt
    21541 gaggcgtccg gggcggatca accgccgagc aggcgctcct cggcggcttc caggctgccg
    21601 gggacgccga gcagcacgat cacgtcgccg ctctcgatgc gcgtctcggc cgcgggcgag
    21661 agcgcgcgga tgccgcgccg gcgcaccgcc gacaccgcca cgccgaactc ctccaggccg
    21721 agctcgccga tgctgcgccc gacccccgcc gccccctccg ggacgatcac cgagcgcagg
    21781 cgcgcctccg caccgtcgcc cccgtcgccc gcgtcgctgc tgccctggaa gaagccgcgc
    21841 atcagcgcgt agcgctggct gcggatctcg cggatgcggc gcaccacgcg gctgagcggc
    21901 accccggtga gggcgagcgc gtgcgaggcg agcatgatgc tggcctcgaa ggcctcgggc
    21961 accacctcgg ctgcccccgc ctgggcgagc ttctccaggt cggcctcgtc gccggcgcgc
    22021 accaccaccg gcaggccggg gcgcagcgcg tgggcgtggt ggatcacgcg cagcgccgcc
    22081 tccagggcgt cgaaggacac gaccagcgcg ctcgcgcgct ggatgccggc cgcgatcagg
    22141 gtctcgcgcc gcgctgcgtc gccatacacc acggtgtcgc cggccgcgcc ggcctcgcgc
    22201 acacgctcgg ggtcgaggtc gagcgcgacg taggccacgt tctcctgctc gaggaagcgc
    22261 gccaggtact ggccactgcg cccgtagccg cacacgatga tgtggcgctc ggtgttgagc
    22321 gactgcgccg ccacgcgggt gagctccatc gagcgcagca gccactccga ggcgacgaag
    22381 cgcatcacca ggcggtcgct cacctgcacg atcagcggtg cgaccagcat cgacagcacc
    22441 agcgcggcca ccgtcgcctg cgcgaggccg tagggcatca ggccgagctc gaggatctgc
    22501 gacagcagca cgaagccgaa ctcgccgccc gcgcacagcc acagcccgga gcgcatcgcc
    22561 gtgcccgccg gcgaaccgaa gaggcgcgag gccgcgaaga ccacgccgaa cttcagcacg
    22621 agcagtgcgg cgagcaggcc gagcaccgcc ggcaggttgc gcacgatctc ggcgacgtcg
    22681 agcagcatgc cgacggtgac gaagaagagt cccagcagca cgtcgcggaa gggcttgatg
    22741 tcctcttcca cctggtagcg gtattcggtc tcggagatca gcatgccggc gaggaaggcc
    22801 ccgagcgcga gcgacaggcc caccagctcg gacagccagg ccagaccgag cgtgatcagc
    22861 agcacgttga gcatgaagag ctcgcccgag cgccgccgcg ccatcaccgt gaaccaccag
    22921 cgcatcaggc gctggccgaa gaccagcacc agcgagagca ggaagaccac cttgaaggcc
    22981 gccaggccga gggtgaacat catctcctcc gccggacgcg acaatgcggg cagcaggatc
    23041 agcaggggca ccaccgcgat gtcctggaac agcagcacgc cgatgacttc gcggccatgg
    23101 cggctgtcga gttccatgcg gtcggcgagc agcttggaga ggatcgcggt cgacgacatc
    23161 gccagcgtgc cgccgagcgc gaaggcggtg atccagccca gaccgccgag ccgcccgagc
    23221 agggtgacga gcgcgatcgt cgccagcacc tgggcgagcc cgagcccgaa cacgatgcgc
    23281 ttcatcgcca tcaggcgccc gagcgaaaac tccaggccga tcgagaacat caggaacacc
    23341 acgccgaact cggcgaggtg gcgcgcgccc gcagactcct gcatcaggtc gagcgcgtgc
    23401 ggccccccga gcgcgccgac gagcaggtag gcgagcaccg gcggcaggtt catgctgcgg
    23461 aagaaggcca ccatcaccac ggcggcggcc agcagcagga ccacgaattc gagggtattc
    23521 agcatgggag cccggcagcg tgtggcgccc gcgctgccgg gcggcggcgc gggtgtttgg
    23581 tatacaatcc gctcgatcgg gagcttgccg gcagcggcgc gccgtcatcc cgccgagcca
    23641 ccggtttccc ttccgcgcca gtttaaagca tcgaatccat ggacccaatt tccgcttcgg
    23701 gcgaaagccg agccgtcgcc ctcgcccgcc gcgtgctgcg catcgaggcc gacgccgtgg
    23761 ccgcgctcgg cgcgcgcgtc ggcgaggagt tcgagcgcgc ggtcgagatc attctcgccc
    23821 gccatggccg ggtgatcgtc accggcgtgg gcaagtcggg ccacatcggc cgcaagctcg
    23881 ccgccacgct ggccagcacc ggcacgccgg cctacttcgt gcatgccgcc gaggccgcgc
    23941 acggcgacct cggcatgatc accccggagg acgtcgtgat cgcgctgtcg aactccggct
    24001 cgagcgagga actgctcacc atcgtgccgc tggtcaagcg ccagggcgcc cgtctgatcg
    24061 cgatgaccgg caagccggat tcgccgctcg cgcgcgaggc cgacgcccac ctggacgccg
    24121 gtgtgggcga ggaggcctgc ccgctcaacc tcgcgcccac cgcgagcacc accgcggcgc
    24181 tcgcgctcgg cgacgcgctc gcggtcgcgc tgctcgacgc gcgcggcttc gccgccgagg
    24241 acttcgcccg ctcccacccc ggcggcgcgc tcggccgccg cctgctgacc catgtcggcg
    24301 acgtgatgcg cccggccgcg gcggttccac gcgtcggcag cgatgccccg ctcacccagg
    24361 ccctgctggc gatgaccgcc gggggcatgg gcatgaccgc ggtggtcgac gccgacgacg
    24421 tgccggtggg catcttcacc gacggcgatc tgcggcgcgc actggaaaaa ggccgcgacg
    24481 tccgcagtgc ccgggtcagc gaagtcatga cgcgcaatcc gcgcagcatc gcgcccggcg
    24541 cgctcgccgc cgaggccgcc gcgacgatgg agaacctgcg catcagccag ctgctggtgc
    24601 tcgatcaggc aggccggctg gccggcgcgc tcaccaccca cgacctgatg ctcgccaagg
    24661 tcatctgaat gcgggtcgac acctggcgcc tgtatccggt cttcgcgctc gcggtgctcg
    24721 cgggcggatc ggtgtggctc gagcgcatca cccggatcga cgacccggtg acgagtgcgg
    24781 agcagaccgg gccggacttc atcgcccacg acacccgcgt cgtcggattc agcgcgctgg
    24841 gcgcacggcg ctatgaactg gtcgccgagc gcctcgaaca cttccccgcc agcgacatca
    24901 cgcgactgca ccaacctcgc ctgcagctgc acggcgagga gggcacgacc acgatcaccg
    24961 cgcgcgcggc ggacgtctcg ccgggcgggg agcaggtcga ccttgccggc gaggtccgcg
    25021 tgcgccgccc gggccaggcg ggggcactgc cgctcgcgct cgactccgag acgctcacgg
    25081 tctggccgga cgcccagcgc gcgcgcaccg actcgccggt gctgatgacg cgcggcacag
    25141 ctcgcgcctc ggcacggggc atgcgcgcgg acaacctgtt cggcacgctc gaactcatcg
    25201 gcgaggtcag cacgacgatg ccaccccgcc gccaaggatc cccctcatga agcaactcct
    25261 catcgccacc gcggctgcgc tgctggtcgc cgcctcgccc gcgctcgccg agaaggccga
    25321 tcgcgaccag ccggtcaaca tcgaagccga ccgcctgacc gtggacgacc gcaacaaggt
    25381 gcacatcttc gagggcaacg tgatcctcac ccagggcacg ctgaccatcc gcggcgacaa
    25441 gctggtcgtc acccaggacg ccgccggctt ccagaacggc gtcgcgaccg cggccggcaa
    25501 gggcctggcg accttccgcc agcgccgcga cggcagcgcc gaatacgtcg agggcgaggc
    25561 cgaacgcatc gagtacgaca gccggaccga gaaggccagg ctgttcaacc gcgccaaggt
    25621 caccagcggc ggcgaccagg tcgcgggcca ctacatcgag tacgacgcga tcaccgagaa
    25681 ctatctcgcc accaacgccc ccggcagccg ccagggtgcg ccggccggca gggtgcgcgc
    25741 ggtgatccag cccaagtccg acggccagcc cgccggcacg caatgacccc ccaccacgag
    25801 cacgaccaca ggaaggagac agcatgagct tcgagatgat catcgccgag aaacgcggcc
    25861 gtgtcggcct catcaccctc aaccgcccga aggcgctcaa cgcgctcaac gaccaggtgg
    25921 tgaacgagat caccgccgca ctgaacgact tcgagtccga cgacggcatc ggtgccatgg
    25981 tcatcaccgg ctcggagaag gcattcgccg ccggcgccga tatcggcgcg atggcgagct
    26041 tctcctacat ggacgcgtac aagagcgagt acatcacccg caactgggag cgcgtgaaga
    26101 cctgtcgcaa gccggtgatc gccgcagtgg cgggcttcgc gctcggcggc ggcagcgagc
    26161 tggcgatgat gtgcgacatc atcatcgccg ccgacaccgc gaagttcggc cagccggaag
    26221 tcaagctcgg caccctgccc ggcgcgggcg gcacgcagcg cctgccgcgc gcggtgggca
    26281 aggcgaaggc gatggagctg tgcctgaccg gccgcatgat ggacgccacc gaagccgagc
    26341 gcgccggcct ggtcgcgcgc gtggtgccgg ccgacaagct gctcgaggac gcgctcgcca
    26401 ccgcggaaac catcgccggc tactcgctgc cggtggtcat gatgatcaag gagtcgatca
    26461 accgcgccta cgagagcagc ctcaacgagg gcctgctgtt cgagcgccgc gtcttccacg
    26521 cctcgttcgc gctcaacgac cagaaggagg gcatggcggc cttcgtcgag aagcgcaagg
    26581 cgaacttccg ccacgactga gcgttcgatc gccagacaca ccgcggccgg cgtccagccg
    26641 gccgcttgcg tttacccgcc ggcatgcgtc atgcggctga aacccggccc cggcacactt
    26701 gcgccgcgtc cgcgcctgcc ctgcagcgca acaccccggg tggctagtca aagaaaatgg
    26761 cgcccgggcg caagtgattg attccttcaa tcaatcccgg atgttgcgat gcacaaaaat
    26821 atgcttgaca gcccgaatcg ggtccgtata atccgaacca tgctgcaacg caacatcgca
    26881 gctaccgaag cgatgttgat gcacccacac ttttcaagga gatccacatg agcaacttcg
    26941 tcacccccga gcagttcgcc gccgccaaca agaccaacat cgagaccctg ctgaccctgg
    27001 ccaacaccgc cttcgccagc gccgagcgcc tcgccgccct gaacctgaac accgcccgtt
    27061 cgctgctgga agacggcgtg gccaacacca aggccctgct ggctgccaag gacgtgcagg
    27121 agctggtgaa cctgcaggtc tcgctggccc agccgatcgt cgagaaggcc gtcgcctacg
    27181 cccgcagcgt ctacgagatc tcgtcgcaga gccaggaaga aatgtcgaag gtcttcgaag
    27241 gccaggtcgc cgagatgaac aagggcgtcg ccaccgcgct cgacaaggct gccaagtcgg
    27301 ctcccgccgg ttcggacgtt gccgtcgccg ccgtcaagtc ggccatcgcc gccgccaaca
    27361 gcgcctacga cagcatgagc aaggctgcca agcaggtcgc cgagatcgcc gaagccaacg
    27421 tggccgccgc gaccaacgcc accgtcaagg ccgtcagcac caccgccaag accgctgcca
    27481 agaaggctgc ctaagcttct tcggtaccgt ctgacgaaaa ggccccgcga tgcggggcct
    27541 ttttgcgtct acccgccgcg tcgcgcgacc gctgcctgcc ggggcacggc tgcaagcccg
    27601 gctcaatcgt agcggatgta gcggaagcgc tcgtccgcgt tcggcgtacc ctccagcgcc
    27661 ccgccctcgc ttgcgggctg ccattgcacc acctcttcga tcttgcgcgc gagggcaaga
    27721 tcgcgtgcgg tgatgccgcg tggcgaatgc gtggacaggc gcacccgcac acggtcccag
    27781 ctcagctcca tctcggggtg atgccaggcc gcctcggcca ggtgcccgac cacgccggcc
    27841 accatcagcg tcgccttcca gccgccgctg cggtagtcgc gcaccagaca gcccgcctcc
    27901 agtcgccagt gcgccagccc cgcaaggccg gcgaggatct cctcctcgtc gagcgcacgg
    27961 atctcttcac tcatcgtcct tctccccttg tcccgagccg cccctgcggc ctgtgcggga
    28021 gaccgggcgc gaacgcgctc agttcccgcc ggcttcggcc gccgcctcgt cggcgagcgg
    28081 cggagcgccg gcctcgtctt ggtagtgatg cgggaacagc cggcgcatct cgccttcgat
    28141 ccaggcctcc gcctgctcgc tcacgtcgtt ggccttgacg cccttgacct cgatcaccgg
    28201 gccgatgctg acgacgatct cgccggcacg cttgatgaag gcgttgcgcc gccagaactc
    28261 gcccgcgttg tgcgccaccg gcaccaccgg cacgccggcg cgcttggcga ggatggcccc
    28321 gcccggcttg tagcgccgcg tcgcgcccgg cgccacgcgc gtgccctcgg ggaagaccac
    28381 cacccacagg ccctccttga ggcgctcgcg gccctgctcc accacctggg tgagcgcatc
    28441 cttgccggcg gagcggtcga tcgcgatgcc ggggatcatg cccagcgccc agccgaagaa
    28501 ggggacgcgc agcagctcgc gcttgagcac gtagcacagc ggcggaaaga tcacctgcag
    28561 cgcgatcgtc tcccacgccg actggtgctt ggagagcacc accgccgggc cggccgggat
    28621 gttctcggcg ccgatcacgc ggtagcggat gccgagcacg tggcggatca cccacatcat
    28681 gatcggcacc cagctcgtga tcagccggtg ccgcgtcatc ggcggcagcc agaagatgaa
    28741 ggtggcgagg aacgcgtagg gcaccgtgat cacggtgagc aggatcgcga acaggatgga
    28801 gcggatcaga tgcacgattc tcttccggtg aagaaggcgt gaggggtggg gaagcggctg
    28861 cgcaccgcgc cgctcaggcg gtcagtgcgg cggcgacggc gtcgaggtcg ggatagacct
    28921 gcgtgccggg cggcagctcg ccgctcgcct gcgtggcctc gcccttgccg gtgagcacca
    28981 gatacggctt ggcgccggcc gcagcggcgg cctggaggtc gcgcaggccg tcgccgacgc
    29041 agggcacatc ggcgagttcg acgttgaagc gctcggcgat ctgcaggagc atgcccggct
    29101 tgggcttgcg gcagtcgcag gtcgaatcgg ccgcgtgcgg acagaagaag atgccgtcga
    29161 gccgcccgcc cgcctgggcc aggctcttga ccatgcggtc gttgatggca ttgagcgtgt
    29221 ccatgccgaa cagcccgcgg ccgatgcccg actggttggt ggccaccacc acccgccagc
    29281 cccactggtt gagccgcgcg atcgcctcga gcgcaccagg gaccggcttc cactcctcgg
    29341 gcgacttgat gtactgcccc gaatcgacgt tgatcacgcc gtcgcggtcg agaatgatga
    29401 gcttcatcac gggctccttg cgggggcgaa gcccgcggcg acgcacgccg cggggacgac
    29461 gacgatcagg ccgacaggcg cgagatgtcc gccacctgat tcatcaggcc ggcgagctgc
    29521 gccagcagcg cgatccggtt ggcacgggtc agcggctcct cggccatcac catgacgtcc
    29581 tcgaagaacc ggtccaccgc cgcgcgcagg ccggcgagcg cgcacagcgc gtcggtgtag
    29641 tcctcgttgg caacgtgcga gcgcaccagc ggcgcgacct cgaccacctg gtggaagagt
    29701 gccttctcgg cggcttcctg cagcagcgcg aggtcgggct cgcccggcgc ggcctcgacc
    29761 ttcctgagga tgttgacgat gcgcttgttg gcggcggcca gggcctcggc ctcgggcagc
    29821 gcacggaagg cctcgaccgc ggcgagcttg gccggcacca ggtcgatgcg cgcgggcttc
    29881 agcgccagca cggcatcgat cacggcgccg tcgcggccgc tctcccggag caggttcttc
    29941 aggcgctcga acatgaagtc ctggagctgc gcggcgaagc cctcggcagt cagcaggccg
    30001 ggcttgaagc cggccgcggc ggtgtcgacg agccagggca gctcgagcgg cagcggcgcc
    30061 tccatgagga tgcgcagcac gccgagcgcg gcgcggcgca gcgcgaacgg atccttgtcg
    30121 cctgtgggca ccatgccgat gccgaagaag ccgaccaggg catcgagctt gtcggccagc
    30181 gccaccgcgg cggcgacgtt gccggcgggc agcgcgtcgc cggcaaagcg cggctggtag
    30241 tgggcctgga tggcgtcggc gacgacctgc ccttcgccgt cggcgagcgc gtagtagcgg
    30301 cccatgatgc cctgcagctc ggggaactca cccaccatgt cggtgacgag gtcggccttg
    30361 gccaggcgcg cagcgcgctc cgccgcggcg acgtcgccgt gcagctgcgc cgcgatcgcg
    30421 ccggccagcg cctcgaggcg ctcgacgcgc tcgagctggc tgccgagctt gttgtgatag
    30481 accaccggcg ccaggcgcgg caggcgggcc gcgagcggct gcttcttgtc ctgctcgaag
    30541 aagaagcgcg cgtccgacag gcgcgggcgc accacgcggg cgttgccggc gacgatgttg
    30601 ctcgggtcgg ccacctgcat gttggagacg atgaggaagc ggtttagcag cttgccggcg
    30661 ccgtcgaaga gcgggaagta cttctggttg gcgcgcatcg tgaggatcag gcactcctgc
    30721 ggcacggcaa ggaactcggc ctcgaactcg cccacataca ccgtcgggtg ctcgaccagc
    30781 gcggcgacct cgtcgagcag gtcggcgtat tcattcaaca aagcgccctg cctggcggcc
    30841 tcggcgagca gctggcgctc gatgtcggcg cggcgctcgg cgaagctggg gatgaccttg
    30901 ccctcggcga gcagcgtggg ctcgtaggcg tcggcggtgg cgatgtcgat ctcgccgcgg
    30961 ctcatgaagc ggtggccgcg cgtggtgcgg ccggaatcga ggtcgagcac gcggcccggc
    31021 accacgtcgg cgccgtgcag cagggtgagc ttgtgcaccg ggcgcacgaa ggtggcgtcg
    31081 ccgtcgcccc agcgcatgac cttggggatg ggcagcgcct tgatcgcgtc ctgcacgatg
    31141 cccgccagca cgtcggcgag cctggcgccc gccacggtcg cggtgtggaa cagcgcctcg
    31201 gccttgccgt ccatgcgacg ctcgaagctg ccaaccgcat ccgcggggat gcccttggcc
    31261 tccatctttt tgagcagcgc cggagtcggc ttgccctcgg cgtcgagcgc gacggacacc
    31321 ggcatcagct tctcggtgac ctccttggct gcggcctcgg aggccacctg cgccaccgtc
    31381 accgccagcc ggcgcgggct ggcgaaggtg cggaaaggcg cgtcggcagg cgccaggccc
    31441 cgggccttga ggccctcggc gatcttggtg gcgaaggtct cgcccaggcg cggcagggcc
    31501 ttcggcggca gttcttcggt gagcagttcg acgagcaggg tcgcggcggt catcacgcgg
    31561 cctccttggt gacgttcagc atcgggaagc cgagggcttc gcgggattcg aaataggcct
    31621 gggcgacggc gcgcgacagg ttgcggatgc ggccgatgta ggctgcgcgc tcggtcaccg
    31681 agatggcgcc gcgggcgtcg agcaggttga aggtgtgcgc ggccttcagc accatctcgt
    31741 aggccggcag cggcaggccg acctccatca cgcgcttggc ctcggattcg tagttggcga
    31801 acagcgagaa caggaagtcg acgttgctgt gctcgaagtt gaaggtcgac tgctcgacct
    31861 cgttctggtg atagacgtca ccataggtga ccgcgcggcc gtcggggccg accgaccaca
    31921 ccaggtcata gacgttctcc acgccctgca ggtacatcgc caggcgctcg atgccgtagg
    31981 tgatctcgcc cagcaccggc ttgcagtcga ggccgccgac ctgctggaag taggtgaact
    32041 gggtgacctc catgccgtcc agccacacct cccagcccag gccccaggcg ccgagcgtgg
    32101 ggttctccca gtcgtcctcg acgaagcgga tgtcgtgcac ggtcgggtcg atgccgagcg
    32161 cgcgcaggct gtcgaggtag agttcctgga tgttcagcgg cgagggcttc agcaccacct
    32221 ggaactggta gtaatgctgc agacggttgg ggttctcgcc gtagcggccg tccttggggc
    32281 gccgcgaggg ctgcacgtag gcggcgttcc agggctcggg gccgatcgcg cgcaggaagg
    32341 tggcggtgtg gctggtaccg gcgcccacct cgaggtcgta gggctgcagc agcacgcagc
    32401 cgcgctctcc ccagaagtgc tggagggtga ggatgacttg ctggaaggtc ggtttcacga
    32461 gtcgggattc ggtggtcatg gtctcgggca gcctccgggc tgcgcagcgc acgcaaaagc
    32521 tgtgatttta ccgggcttcg gccccgcgcg ggcgtgccgc ggcggcgagg gccgcgagca
    32581 ggatcgggat caccgcggcg aggagcgcga ggcggtcgcc ccagcgcgcg tagggggtcg
    32641 ttccctggtg gccgcgtacc tcggcatgca gcacgccgcg ctcgaacgcg ggcagcacgg
    32701 cggcgacgct gccgtcgggc tgcaccaccg cggtcatgcc ggtgttggtc gagcgcagca
    32761 tcgggcgccc ggtctcgagc gcacgcacgc gcgcgatctg caggtgctgc ggctgggcga
    32821 gcgagtcgcc gtaccaggcc aggttggaga ggttgagcat cagcgtggcc gcgggcagcg
    32881 cgcggatgag ttcggcgccg aagaggtcct cgtagcagat gttgagcgcg acctgctggt
    32941 cgccgaagcg catcggctgc tggtcgggcg cgcctcgggt ctggtcggac atcgggatct
    33001 gcgccagctc gtagaaccag ccgaaaagcg gcggcgagta ttcgccgaag ggcaccagat
    33061 gctgcttggc gtagcgctgg acgggcgcgc tgccgaggct gatcgcggcg ttgtagatgc
    33121 gctcctcggc gtcgcggcgg aaggcgccca tcaccaggtc gcccccggcc tggctggcga
    33181 ggccggcgaa gacttcgaga tagccttcgg ggaggcggtc gagcagggtc ggcaaggtgg
    33241 tctcgggcag caccaccagc gcaggcgtct gcggctgcgc gaaggcctcg cgcgcgagct
    33301 cgaggttgac ccgcagcacc tcctcgaagc gcgccggatc ccacttcagg ctctgcgcga
    33361 agtcggtctg caccagcgcc accttcagcg gcgcaccggc cggctgggtc caggcctggc
    33421 cgagcagcgc gaagccggcg gcgaagggca cgaccagcgc cagcgccggg cgccacgcga
    33481 gcagcgcacg cacgccgccc gcccgcagcg cgaaggcgca cagcgcagcg acgaaggcgc
    33541 tcagtccgcc gacgccgtac acgcccagca ccggcagcag accggcgagc gggctgggcg
    33601 gagtctgtgc atagccgacg gcgagccagg ggaagccggt gaacaccacg ccgcgcagcc
    33661 attcggacag cagccagagc gccccgaaga gcgccgccgc gcgcaccggc gcacgcgcga
    33721 tgccgccgcg gcgcagcgcg acgaaggccg cgccggcgag cgccggatag agcgcgaggt
    33781 aggcgcagaa cagcccgatc gccagcgcgg cgaccggcgc gggcacgccg ccgtagcgtt
    33841 cgagcgcgac gtagagccag gacaccccgg cggcgaaggc gccgaagccc caggcgaagc
    33901 cgagcgcgaa gcccgcgcgc gcgcgcgccg cgtcggcgag cagccaggcg agcacgccga
    33961 ggccaaggaa ggcgagcgca aacagcccga agggcgcaaa cgcgaacacc gtcgcgcccc
    34021 ccgcaagcag cgcgaccagc caggcgcttc gcatcacgcc tgttcgggca gcggctgcgg
    34081 caggcgctcg acgatcaggg tgtagacccg ccggctgtcg gcacgcagca cctggatcct
    34141 cagcccctcc agctccaccg cctcgccgcg cttgggcagg cgaccgaagt ggcggatcac
    34201 cagaccaccg acggtgtcgt attcctcgtc gctgaagtgg gtggcgaagg cctcgttgaa
    34261 gtcctcgatc tcggtcgtgg ccttcacgcg gtagcggccg ctgtggtcga ggcggatgtt
    34321 gtcaccgacc tcgtcgaagt cgtattcgtc ctcgatgtcg ccgacgatct gctcgagcac
    34381 gtcctcgatg gtgaccaggc cggccacgcc gccgtactcg tcgaccacga tcgccatgtg
    34441 gttgcgcgac acgcggaatt cgcgcagcag cacgttgagg cgcttggatt cgggcacgaa
    34501 caccgcgggg cgcagcatgt cgcgcaggtc gaactcgcgc ccggcgaagt agcgcagcag
    34561 gtccttggca agcaggatgc cgacgacgtc gtccttgccg tcgccgatcg ccggaaagcg
    34621 cgagtgggcg gtgtcgatcg cgaagttggc gatcgtgtcg atcgggtcgt ccagatgaat
    34681 gcagtccatc tgcgcgcgcg ggatcatcac gtcgcgcacc tgcatgtcgg acatctgcag
    34741 ggcgccctcg atgatggtga gggcgtcggc gtcgatcagg ttgcgatcga aggccgaatg
    34801 cagcagcgcg aggagttcat cgcgatcttc cggttcgcgc gagagaaggg ccgaaagtcg
    34861 ctcgagtaag gaaggtttgg gggaactgtc cattttgggg gtcggtgtct ccgcttcagg
    34921 cgctcaaggc gtaggggtcg gcgtagccga gctcgcgcag gatggcggtc tccagcgctt
    34981 ccatctcggc cgcctcggtc tcgttctcgt gatcgtagcc ctgcaggtgc agcatgccat
    35041 ggacgacgag gtgggcgaag tgcgcctcca gggtcttgcc ctgggcggcg gcctcgcgca
    35101 ccaccaccgg tacgcacagc accaggtcgc cggcgagcgg tacgtcgccg cccgcctcgg
    35161 gcaggccggg cagcgcctcg ccctcggcgt aggcgaaggt cagcacgttg gtggcgtagt
    35221 ccttgccgcg gtagtcgcgg ttgagcgcgc gcccctcggc ctcgcccacc aggcgcacgg
    35281 tgacctgggc gctggcgcgc agcgccgcgg tggcccagcg ccggatgtgg ttcttcttcg
    35341 ggcagttggc cttgtcctcg ccctcgaccg ccttctgcac ctgcagcttc agcaccggcg
    35401 agtgctcgcc cgcaggcagc gcgagcggct cgacgaagct caggtcgtgg tgcacatcca
    35461 cgcgcagcgt catcaggttg caggcgccgg gctgcagcga cagcatcggc accgcgctgt
    35521 cgtcgtcggc ctcggcctcg atctcgaggt cgccccaggc cttctcgggg aaggcgagca
    35581 gcagcttgcg gccgtcgccg agctcgatct ccaggcgctc ggcgcggacg cgcgcggcct
    35641 tgccttcggc atcgatggcg acgatcctgg ggtaggtgcc ggccgacctg tccgcgaccg
    35701 tcttgttcgt cttgtcggtc ttgttcgtct tgttggtctt attcgccatc ttcggcttcc
    35761 tgctcctgcg gctccggctg ctggcgtgct gcgcgggccg cggccttctc acgctcgagg
    35821 cgcgccgcct cgaggtcgta agcttcgacg atgcgtgcga caagcggatg acgcaccaca
    35881 tcctccttgc tgaattcggt gaacgcgatg ccgcgcaccc ccgccagcac cgcgcgtgcc
    35941 tccttgaggc cgctgcgctg gccgcgcgcc aggtcgacct gggtgaggtc gccggtgacc
    36001 accgccttgg cgccgaagcc gatgcgggtg aggaacatct tcatctgctc gggcgtggtg
    36061 ttctgcgcct cgtcgaggat gatgaaggcg ttgttgagcg tgcgcccgcg catgaaggcg
    36121 agcggcgcga tctcgatgct gccgcgctcg aagagcttgc cgacgcggtc gaagcccatg
    36181 aggtcgtaga gcgcgtcgta gagcgggcgc aggtaggggt cgaccttctg cgccaggtcg
    36241 ccgggcagga agcccaggcg ctcgccggcc tcgaccgccg ggcgggtgag gatgatgcgc
    36301 tcgacgaggt cgcgctcgaa ggcgtcgacc gcgcttgcca ccgccagata ggtcttgccg
    36361 gtgcccgccg ggccgatgcc gaaggtgatg tcgaagtcct ggatgttgcg caggtagtcg
    36421 acctggcgcg gcgtgcggcc gtgcagctcg gtgcggcggg tgagcagcac cggcgcgggc
    36481 tgcgccgcct cgcccttgct ggcgatctcg atgaggccga gctggacctc gtcgcgcgac
    36541 aggtccttgt cggcgagcgc gtagaagtgc ttgagcgcca tctcgccgcg cagcacctgc
    36601 gccggatgcc cggccagggt gaagtgctcg ccgcgccggc tcacggtgat gtcgaaggcg
    36661 ttctcgatct ggcgcaggtt ctcgtcgagc acgccgcaca gcttggccag gcgggcgtta
    36721 tccaccggct cgaagaagac ttccagggtt ttcgccattc aggattcccg ggtgaggatt
    36781 tcgccgcgca ggctgtgcgg cagggctgcg gtgatgcgca cctccacgaa ctggccgacg
    36841 aggcggtcgc ggtggggcga atcggagggg aagttgacca cgcggttgtt gtcgctgcga
    36901 cccatcatct cgacctcggg gtgcttcttc gccgcgccct cgaccaggat gcgctgcacc
    36961 gtaccgacca tggcctcgct gttggcctgg tactgcgcgt cgatgcgctt ctgcaggcgg
    37021 gcgagccagg cgagcttggt ctcctgcggc accgggtctt cgaggtcggc cgccggcgtg
    37081 ccgggccgcg agctgtatac gaagctgaag gagccgtcga agccgatgtc ctcgatcagc
    37141 ttcatggtct tctcgaagtc gtcctcggtc tcgcccggga agccgacgat gaagtccgag
    37201 gtcagcgaaa gatccggccg cgccgcgcgc agcttgcgca ccaccgactt gaattccagc
    37261 accgagtagc cccgcttcat cgccgccagc acgcggtccg agcccgactg caccggcagg
    37321 tggagctgcg acaccagctt cgggatcctg gcgtagcagt cgatcaggcg ctgcgtcatc
    37381 tcgcgcggat gcgaggtggt gtagcggatg cgctcgatgc cggggatctc ggcgacgcac
    37441 tcgagcagga aggcaaagtc gccctgctcg ccgtcctcgc gcaccagctc gccgcgccag
    37501 gcgttcacgt tctggccgag cagcgtcact tccttcacgc cctgcgccgc cagcccggcg
    37561 atctcggcga gcacgtcctc gagcggacgc gacacctcgt cgccgcgggt gtagggcacg
    37621 acgcagaagg tgcagtactt cgagcagccc tccatgatcg acacgaaggc gctcgcgccc
    37681 tcgacgcgcg ccggcggcat ggcgtcgaac ttctcgatct cggggaagga gatgtccacc
    37741 tgcgagcgcc cgctctgctt gcgcgcctcg atcaggctgg gcaggcggtg cagggtctgc
    37801 gggccgaaca ccacatccac atagggcgca cgcttgacga tggcctcgcc ctcctggctg
    37861 gccacgcagc cgcccacgcc gatgatcagc ccgggcttct gctgcttgag caggcgcacc
    37921 cggccgaggt cgtggaacac ccgctcctgc gccttctcgc gcaccgagca ggtgttgaag
    37981 aggatcacgt cggcctcttc cgggttgtcg gtcttgacca gttcttcgtg ggcaccgagc
    38041 acgtccgcca tcttgtcgga gtcgtactcg ttcatctggc acccgaaggt gcggatgtag
    38101 agtttcttca tctattcggg aaagtcaggc aaagccttgc ggcaggtcgg gcgggcatcg
    38161 cggcatccat caaggcctgg accgggcctt gggcatcggc gccgccgcct cttccggggt
    38221 gaggatccac acccgatgca cctggccgtt acggtccatc agcatgcgca ccacgtactc
    38281 ccccgccaca tgcgagggca gcacgatgcg gttgtgggta tcgcgaatct gcgcaccggg
    38341 actgaggcgc agcgtggcat ccttgacctg caccacgccg ggcgagggga acgccatctt
    38401 caccctcgcc gcgtcgtcgg gaatcggccg cggcagcgcg gcgaagacca gggtcgaagc
    38461 gaggccggaa agaccggcca ccaggacgga gagaaagtgc gggcgcaagg aggggccgga
    38521 gagatccggg acgttgggga acaggccggg gatgatcgtc catcgccccg gcgatgtcaa
    38581 tgcaaaagcc ttataaatca agcgttccac cgactgcaaa agcccgcccc gggaagcact
    38641 tgccatgcgt gctgtaccgc tgcgcgggag cagactcgcc cgcgaaaacg agccgtgtca
    38701 ccgctcgttc gcgggcaagt ccgcccccac gagcgcaacc cgggcccggc aagtcgtcga
    38761 ttcgacgccc ctggcgcttg acgaccccgc cgcacacccg ctatattcgc gcgctctgtt
    38821 ggtgatgtag ctcagacggt tagagcgatg gattcataac ccataggtcg gcggttcgat
    38881 tccgcccatc accaccaaaa aaatccagca aaaaggccga ccctgcgtcg gcctttctgc
    38941 tttggatccg cggggcaagt cgattgcccg gcttcgcgcg acgatacgga tggccaccgt
    39001 gccggtgcag tcgatgaaca gccgtgcccg tgcgtccgca tgcagcccag tgcaacggat
    39061 cccgggcctt caagcgaacg tgcgcgcagg agccccgggt cccgcagccc atgcgaatcc
    39121 cctggagatc cgcgccgacc acgcgtcatc cttgcggggc ggactcaagc gggccgacgt
    39181 tttccgtcgc gctccgcagg caaaccgcgt cttcctccac ggacgaactc cccgtaacga
    39241 ggcatgattg cctcatgtcc tccacccacg ccgcaaccct ccccaagcag ccccaccgcc
    39301 gtccgcccca tcgcgacggc gggcggcgct tcctgctgct ggcggggggc tactggaact
    39361 gcgagcgcaa gtggcaggtg cgtgcgacgg tgctggcgct gatcctgctc accatggcgc
    39421 aggtgggact ggcgatctgg gtgagctact ggaaccgcga cctcttcgac gccctggagg
    39481 atcgcgcgct gtccgagctg ctgcagctgg tgggggtctt cgtgctgatc ttcgccctca
    39541 ccatgggggt gaccgcgctg cacatgcacg tcaagcgccg gctgcagctc gactggcggc
    39601 gctggctcac cgacctgctg ctcgagcact ggctggcgca cggccacctc taccgcctgc
    39661 aattcaccgc cggcgagcac gacaacccgg acggccgcat cgccgaggac atccgcatcg
    39721 ccaccgacgt ggcggtctcg ctcgcccact cgctgctgtt cgcgctgctg atcctgggca
    39781 gcttcatcga catcctgctg agcgtgtcgg gcagcgcgcc gctgccgggg acctcgatcg
    39841 cggtgcacgg ctacatggtg ctcgccgcct tcctgtacgc gggcgtgggc acggcgctcg
    39901 ggctcatgct cggccgcccg ctgatccgcg ccaccaaccg cctgcagacc gtcgaggcca
    39961 acctgcgctt cggcctggcg cgggcgcgcg agcacgccga gccgatcgcg atgatgcacg
    40021 gcgagccgca cgagcgccgc gaggcggcgc gcctgttcga cgatgtcggg cggggctgga
    40081 accggcagac cctggcctac ctcggcatcg tgtccttctc caccggctac ggcaccctgc
    40141 tgccggtgtt cccgatcctg atcgcggcac cgcagtacat cgccggcgcg atgacgctgg
    40201 gcgtgctgat gcaggcggcg caggccttcc agcgcctgac cacggcgctg tcctggccga
    40261 tcgacaacct cggcgagctc gcacgctgcc gcgcctcgat cgaccgcgtc gccagtctgt
    40321 acgaggacat gctcgcgctc gaacgcgcgg aggcacgcag ccgtggccgc gagcgcatcg
    40381 cggtgtgcgc ctcgccccac cccgaactcg agctgcgccg gctgcgcctg cagaccccgg
    40441 cgggcgagct cctgctcgac gacttcgacc tgcgcgtgcg ccgcggcgaa cgcgtgctga
    40501 tctgcggcga tcccgcggtc acgatcagcc tgttcaaggc ggtcgccggg ctgtggccct
    40561 ggggcagcgg cgaggtgcgc ctgccggccg ggcgcgacct gatgttcgtg ccgcgccagc
    40621 ccttcctgcc cgcgggcggc ctgcgcatgg tgctgagcta ccccgacgac gccgatcgcc
    40681 accccgacgc cgtgctcgag cgcgcgctcg aatgcgccgg catcgcgtgg ctggcgccca
    40741 agctcgacac ccaggaggac tgggggcgcg agctgccgct gcgcatccag cagcgcctcg
    40801 gcctcgcgcg cgtgttcctg caccagccgg cgtggatctt catcgaggag gccaccgacg
    40861 cgctcgcgcc caaggaagag gtcgactccc tggagctgct gcaccacgag ctgccgagct
    40921 cgaccctgct ggtgatcagc cggcgcgcgc gccagaacca tttcttcgag cgccgcctgt
    40981 tgctgcagcg cccgcgcacg ggcgtgcagc ctccggccgc gcacactgcg cggccggaag
    41041 ccccgtccct acccgaagcg tgagggcagc cagccgcgct ccacgcactc gcggaagcac
    41101 cacgccggcg tggtctcggt cttgtagctc cagaagaacc agcccgccag gcgctcgaac
    41161 gtcatcagct ggctgtcgcc ataggcgcgg ctggcgacgt cctgctggaa gtcgtccatg
    41221 tgctcgaggg cgtggttgaa cggcccctcg gcccacagcg acaccacctt caggtccagc
    41281 cccaggctcc actcgccaca caccgccggc aggccgagct cggcgttgat cgcgtcggcc
    41341 tcctcgcgcc agtccaccgc cgccttgcgg atgtggccgt ggatgtccat gtcgatgtcg
    41401 cagcgctcga agcactggta gcggtggtag tcgaacacca cgttgcggaa ggccggcgcc
    41461 tgcatgaagc cgaggtattc gcggaagctg cggaagccgt cgtggaacac caccgcgacc
    41521 ttctcgggtg cgcagtgctt gcggatgcgc gcgtaggcct cgagatagta ggccttcagg
    41581 tagtcggtgg gcacgtccca gcgcggctcg ttgagcagct cgatgccgtg cagcgcagga
    41641 tgcgcgtggt agcgctccgc caggcgctcg agcaccgaga gcgagtgctc gagatactcc
    41701 ttcctggtgt gccactccac cacgtccttg atgccgccgt tgtcgaagcc gttctggcag
    41761 ccgggcgcgg cgtgcaggtc gatgatcacc gcgaggccga gctcccgcgc ccagtcgagc
    41821 gcgcggtcga gcacctcgat gccgccggtc acgaaggggt ggcggtgggc gccgtacttg
    41881 gggtggtagg ggtagtcggg gccgaagatc cagtgcccga tcgggatgcg caccgcgttg
    41941 aggccgcgcg cggcgatcca ggcgaagtcc tcgcgggtga cgaagctgtc ccagtgccgg
    42001 cgcaggcgct cggtggcggc ggggccgagc tcggcgcacc aggtggtctc gtcggtcgcc
    42061 tccaggccct cgaacaggct gggcaccatc cacttctcca gcagcagcca gctacccagg
    42121 tttaccccgc gcagcttggt acgcgtcgtt tccatgagaa cctcccctgc ccggatcggg
    42181 cgtaatggac atggctcatt ctggcagcca atcgcccccg gcgaccgtga aaaagctcgc
    42241 gccccgccgc acccccgccg aatgcgtcac ggccctgttc gcgcctgccg gcgctcctgc
    42301 atagcaccca ctcgtggtgt cggattgggg aagcgacgcc cccgtgcacg tggcagaatc
    42361 gcgcccccgc ttccctgccc gagtccgccc catgcgcacc gtcgaacacg tcgtcaccca
    42421 cctgatcgtc cacgccctgg tgcgcgagcc cggcacgccc tcgcgcctgg tgctgcgcga
    42481 ggcgccgtgc gcgctcgacg ccgcggcgtt gcgcctggcc gagcgcctgt gcgcgcagta
    42541 cgagagccgc aacgccaagg gcttcggtcg cttcgaggat gacgaggaga gctacccgct
    42601 cgcgcgctgg ctgcgcgagc accaggtcga cgagaccctc gacttcacca ccctgtcgcg
    42661 ccagctcgcc gagcgcgtgc aggccatcgc cgacgaggag gagctcgagg acggcggcca
    42721 cctggtgctc gcgcgcatcc gcgagggcga tggcgacagc ctgtgggtgg ccctgctcgg
    42781 cagcgccgag ggcgtcgcga tcggcggcag cctggagccg ctcgactgca cccacgtgga
    42841 tttctccgcg ctgcacgccg ccggccgggt cgacctcgcc ggctggcggc gcggcgacga
    42901 gcgctacctc ggcttcctgc gcggccgcgg caagggcggc gcctggttca agcgcgtgct
    42961 cggctgcagc gatgtgatgg tggcgctgca ggagaccaag aagctggttg ccaccctcga
    43021 ccgcttcgtc gacaccgagc gcctcgcccc ggccacccgc gacgccgtgc tcgaacgcgc
    43081 ccacgactac ctcgacacgc tcggcgaggc cggcgcgccg gtggtcttcg aggagctcgc
    43141 gcgcgaggtc ttccccgagc agcccgagcg cctggacgcg ctgctcaagg ccgaggagac
    43201 gaggatcgcg cccggcttcg tgcccaaccg ccgcgccatc cgcccgctgg tgcgcttcag
    43261 cgccagcgcg gagaactgga agctggagtt cgagcgcagc ggcctgcact ccggcgcggt
    43321 gcactacgac cgcgccaccg acaccctggt gctgtcggga gtgccggact acctcaagcg
    43381 catgctggac gaggaagaca agggctgaga
//
LOCUS       DAOTIN010000018        41746 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_980_length_41746_cov_8.702766, whole genome shotgun sequence.
ACCESSION   DAOTIN010000018 DAOTIN010000000
VERSION     DAOTIN010000018.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 41746)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 41746)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41746
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_980_length_41746_cov_8.702766"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(174..2720)
                     /locus_tag="P5537_04665"
     CDS             complement(174..2720)
                     /locus_tag="P5537_04665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS-assembly protein LptD"
                     /protein_id="HRV77370.1"
                     /translation="MLPTTRIRLIPLLLLGLSGAAFAQSLPTLQVAPDLLRPAPTATP
                     ARAVTPASAAPASKAPAPEPMSVPALAPVPAPGPAPVAAPTPQPAATPTPPVTATATK
                     DVARATAAPPAAPPAAERPALAPGETAVSALRIHGERGVELVAEGEAELQRDDTVLTA
                     ERVTYREPTDEVLAEGDVVLSRGGDTIRGPKATLVVGDRVGSFETPTYELSRARPPAL
                     AGDAPRTVAGSGEADLLRLEGENQYRLANATWTTCSPQDPDWYIRARELELDYDREVG
                     TARGSSIVFMDTPIFWMPWAEFPLSGQRQSGLLPPTFGSSNKTGVDFTQPYYWNIAPN
                     YDATLAPRIMTRRGVQFGGELRYLGEDYQGTTRLEWMPNDKVTGEERRLGSIQHQHRF
                     APNFYGTLDLNAVSDDAYFEDLSSSIGVASRVNLLREGRLIYAGGWWTASALAQRYQT
                     LNPDPDVRNVEPYRRLPQLRLDAARADLAGGMAGLLETEFVRFAHRETDRDEASRFVA
                     YPQLSLPMQGAAWFVTPKAGVHYTSYDIDRAVPKAGKPDSITRSVPIVSLDSGLFFER
                     ESHYFGKDYLQTLEPRLFYLRVPSRNQDDIPLFDSNRFDVGFAQIFAENRYSGSDRIG
                     DANDLTAAVTTRFIDAETGVERLRALIGQRYYFSDQEVYLYNEDELRRAGTGNEILAG
                     LGGRVTSTVTVDSYAQYNTETSRTERLNASVRYQPGFARTLNLSYRYAPNLRVDDDIV
                     GLKDIDVSGQWPLARNWYGVGRVTHSLKDDRITEAVAGIEYDGGCWVFRTAVHRFAID
                     EDDVTNAIFVQLELNDLAGIGSNPLSLIKRSVPGYGKINDSSANRVFGED"
     gene            2823..3863
                     /locus_tag="P5537_04670"
     CDS             2823..3863
                     /locus_tag="P5537_04670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004381468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HRV77371.1"
                     /translation="MHRLEQLRTWLAATLPGQSFELAPASADASFRRYFRATFADGSP
                     SRVVMDAPPEKEDVRPWLHVAGLFGAAGAHVPEVLAQDLDQGFLLLSDLGSTTYLQAL
                     KAHDDPQQAARTAHHLYADALGALAAIQCASRPSVLPEYDRALLLRELQLFPEWYIAR
                     HKGVTLTEAETAMLNTAFERILAVNLAEPQVFVHRDYHSRNLMLLEPAEGRGANPGII
                     DFQDAVYGPISYDLVSLFKDAYIRWDEEFILDLLIRYWETAKKLGLPVRAEFADFHRD
                     FEWMGVQRHIKVLGIFARLYHRDGKDGYLADMPLVMDYLRRACKRWRDLGPLLKLLDR
                     LEPENVQVGYTF"
     gene            3881..4567
                     /locus_tag="P5537_04675"
     CDS             3881..4567
                     /locus_tag="P5537_04675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HRV77372.1"
                     /translation="MILAAGRGERMRPLTDHTPKPLLSVGGKPLIVWHIERLRASGFR
                     ELVINHAHLGHRLEEALGDGTAFGVRIAWSPEASALETAGGIRHALPLLGDQPFVVVN
                     GDVFCDADFTSLRAAAEGLHADGPLAHLLLVDNPEHHPEGDFHLDAAGLLHAEGAPRL
                     TFSGLGAYHPALFAALADDTPAKLAPLLRAAMNAGQVTGRHHAGRWIDVGTPRRLADL
                     DCELQHKRPS"
     gene            4564..7149
                     /gene="mprF"
                     /locus_tag="P5537_04680"
     CDS             4564..7149
                     /gene="mprF"
                     /locus_tag="P5537_04680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004333837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HRV77373.1"
                     /translation="MNTDKAKRLIETVLDQARRIRPAVVPALAVLVLALAWTAVSHLV
                     GEVSYAEVAAALAATPDRALAIALGCTLLSFVALMVYDLGALDFIDRKVPRNVVALTS
                     FCAYSVGNTVGFGPLTAGAIRYRFYTPYGLEPDEVARIVAFVTAAFAIGLAATAAIGL
                     LVAADELAMLSVAPFVLQLIGGGMLAAFVALCLAAGEGRTVSLFGSPARLPSWRQMVR
                     QLVATIVDIGASATVLWVLLPAGSIDLPAFVAIYAVAVGLGVVSHVPAGLGVFETVIV
                     AALSGRLPIDQILSALILYRVIYHLVPLILAVLLITGLELRKAARTPLMAAALKAGHR
                     LAPPLIGAFTLVLGAVLVFSGVTPASEEALDVLSDVVPLPLLEGAHFLGSVLGMALLI
                     IARGLVYRLDGAWWLAVIVVPLSAILAFFKGLALGEALMLTALFAALLASRRAFSRHA
                     SLLHQAMAPGWLAAMGVLLVTAVAILLFVYKDVDYSHSLWWQFEFYSEAPRSLRALIG
                     ITLTAGLGAWWTLMKPVGVRSALPDEEALERARRIVAAQAHVDAGLVAMGDKRLLFSE
                     DGRAFIMYAIQGRSWVALSDPVGPRETWPELVWNFAELARHAGGRAVFYQVAPESLGL
                     YADAGLMAFKLGEEARVRLSEFDLKGGKRASLRQSLNRAERMGLSFEILAGPALDACM
                     DELSALSGAWLAQHKAREKRFSLGAFDPAYVRRQPVALLRQAGRVVAFANVLLTDLKQ
                     EATVDMMRFSADAPNGAMEALLLHLILHFQREGYEWFLLGMAPLSGLSASAAAPIWHR
                     VGRTVFEHGERFYNFSGLRAFKAKFLPEWQPRYLAVAGGINPMLALADITVLISGGLK
                     GVIGK"
     gene            7146..8492
                     /locus_tag="P5537_04685"
     CDS             7146..8492
                     /locus_tag="P5537_04685"
                     /inference="COORDINATES: protein motif:HMM:NF017835.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AcvB/VirJ family lysyl-phosphatidylglycerol
                     hydrolase"
                     /protein_id="HRV77374.1"
                     /translation="MTLPHRFLASLALAAMLSAGAPGTSAADPEMTIGAPLKILPATP
                     PTGAVVLFSDADGWDGPERGAAEALAKQGLVVIGIDLEGVMRRMRARHDDCSILIGEI
                     EAVSHELQRQTGAHAYHFPVLAGVGEGGTMALAVADQAAAATLAGAVAVDPLPAAALR
                     RALCGHDGRPTDGTARLMPPPLPFSVELIASTDAGQAAHTLVARLAAGRHDVQVTDSP
                     EKPAAALLAGVGRAGHPRQDDALGDLPLIELPALGPGTGAFAILYSGDGGWRDLDKDV
                     AALLQREGLPVVGVDVLRYFWSQRSPEQGARDLARIIDAYARRWKATRVVLIGYSFGA
                     DVLPALYNRLPADMKGRVAQISLLGFATRASFEVTVSEWLGHAREDSVPTLPEALRID
                     QRLLQCFQGDEDDEAACTGLGAGAEIIRTSGGHHFDGDYEALARRILHGVERRSPH"
     gene            8536..9879
                     /locus_tag="P5537_04690"
     CDS             8536..9879
                     /locus_tag="P5537_04690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011766616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P N-terminal domain-containing
                     protein"
                     /protein_id="HRV77375.1"
                     /translation="MNAPGTAPMDTPPFRARRARLLQRMQAAGGGVAILPTAPERVRN
                     RDAHYAYRHDSYFYYLTAFREPEAVVVLVAGKETKQILFCREKNEEREIWDGYRWGPD
                     AAREAFGFDEAWTIGDLEKRLPDTLADQPLLWTSLGYDNDWDAKVLGALNAVRDKART
                     GLTPPHSVRDLRAELDEMRLVKDASELATMRRAARISADAHGRAMRATRPGRFEYEIE
                     AELLHAFRAAGSQAPAYTSIVAGGANACVLHYVDNDQRLKDGDLLLIDAGCELDGYAS
                     DITRSFPVNGRFSGAQRDVYELVLAAQVAAREATRPGAHWNQPHDAAVKVLAQGMLDL
                     GLLQGSLDGVLESGDYRRFYMHRTGHWLGMDVHDAGEYKLGGEWRPLVEGMVLTIEPG
                     CYIRPADDVPEAFWNIGIRIEDDAVVTAGGCELITEDVPKAITEIEALMRDTRHA"
     gene            9872..11083
                     /locus_tag="P5537_04695"
     CDS             9872..11083
                     /locus_tag="P5537_04695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent monooxygenase"
                     /protein_id="HRV77376.1"
                     /translation="MPENAPERVHDLLIVGAGPVGLALALALKDAGLDIVLADARARE
                     AVTKDPRDLALAHGTRLTLQRLGVWNTLPRTAIEHIHISHQGGLGRTLIDAAEHGLPA
                     LGYVASAGALAAALREAVDAAGIPVFDETEITNLAAGEEDVIASLAGAGRPAPTLRAR
                     LAACAEGGLRAGDPNVVEHDYGQHALIADVQVAGGHRHTAFERFTPQGPVALLPKGDG
                     YALVHVAHPDTADELLALDDAAYLARLQAHIGGRARLTGVGPRLRYPLVLRYRRSTIA
                     QRTVWLGNAAQTLHPVAGQGFNLALRDVWALADALLRAREAARRGAADTAPGPFDAGA
                     ATVLARYANARGLDRLGTIRFTDTLVRVFSNDFAPLRHARGAALLALDLIPPLRNFLA
                     RRMMFGARAWP"
     gene            11253..12344
                     /locus_tag="P5537_04700"
     CDS             11253..12344
                     /locus_tag="P5537_04700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance/C4-dicarboxylate
                     transporter family protein"
                     /protein_id="HRV77377.1"
                     /translation="MDTSASTGNSDDLRDKFRQGLRELSPAYFGMAMATGIVSLSAHM
                     QGWKWLATTLFWINASLYGVLWLLLLLRIAWHPGAVRTDLLDHLRAPGFFTTVAASGV
                     LGTQCLVVADSLGGAITLWCVALVLWLLLTYTIFTMLVVKAEKPPLDQGINGGWLLAV
                     VATQAVAVLGTLIATRIPQPYRLELNFFALSMWLWGGMLYIWMMSLIFYRYTFFRFSP
                     ADLSPPYWINMGAMAISTLAGSQLILNAPHAPFLESLLPFIKGFTVFYWATGSWWIPM
                     LIVLAAWRHGVMRFPLRYDPLYWGAVFPIGMYSACTLRLHEAMALPFLDRIPPVFLVI
                     ALCAWALAFTGLVLDLLARVRAPARATRA"
     gene            complement(12355..13155)
                     /locus_tag="P5537_04705"
     CDS             complement(12355..13155)
                     /locus_tag="P5537_04705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HRV77378.1"
                     /translation="MSFTLRKLFAAAFGTLALAAGNAAVAADRLVIAATPVPHAEILE
                     FVKPMLAKEGVELEVKVFTDYVQPSMQTNEKRVDGNFFLHQPYLDAFKQKQKNDIQTV
                     VTKVHVEPLGAYSGKHKAVADIPEGATVAIPNDPSNSGRALLLMAKNGLLKLKDLNNI
                     SATQKDIAENPRKLRIRELEAATLPRVLNQVDLAVINTNYAIEAKLNPLKDSLFIEDA
                     SSPYANLLVARDDNANSPAIRKLAAALNSPEVKQFLADKYQGAVVPAF"
     gene            complement(13179..13838)
                     /locus_tag="P5537_04710"
     CDS             complement(13179..13838)
                     /locus_tag="P5537_04710"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HRV77379.1"
                     /translation="MDLSVIDWSDIWIATWETLVMTGVSLFFTILLGLPLGILLFVTA
                     KRQLLEQGLVYTVLSFVVNVLRSVPFLILLIVMIPVTVILIGTSLGVEGAIPPLVVGT
                     APFFARLVENVLREVDRGVIEACQAMGIRTSRIIFGALLPEALPGLIAAVTVTAITLM
                     SYAAMSGVIGGGGLGDLAIRFGYQRFQTEVMVITVALLVVLVQIIQYSGDRLVLYFTR
                     K"
     gene            complement(13838..14866)
                     /locus_tag="P5537_04715"
     CDS             complement(13838..14866)
                     /locus_tag="P5537_04715"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HRV77380.1"
                     /translation="MIRIENLRKTYRAADGREVEALADIDLEIGAGEVFGIIGRSGAG
                     KSTLIRTLNLLERPSAGRVLIDGEDITQLDSEGLYALRRRVGMIFQHFNLLNAKTVAD
                     NIDWPLKATGHGNAAERAARVRELLDLVGLSEHGHKYPSQLSGGQKQRVGIARALANR
                     PQILLCDEATSALDPETTQSILRLLLDINRQLGLTIVLITHEMQVIRTICDRVAVIDG
                     GRIVESGRVADVFLHPQHPVTRSMVAQSDALAAASFDPAHAYMKDKLRGTLVRLTYIG
                     DVTYQPILSRIMAGARVQVTILQGEVSSIKDVPFGQLLLELEGGEDDIRAVFAELDRH
                     QIHHEVLQ"
     gene            15007..16155
                     /locus_tag="P5537_04720"
     CDS             15007..16155
                     /locus_tag="P5537_04720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aspartate aminotransferase family
                     protein"
                     /protein_id="HRV77381.1"
                     /translation="MQHDDTLSPATLAAQGLGTIPMPHRDIVPPIHMATTFERAEDGS
                     LPGGRIYARDASPAYDPAEALLCRLEGGAAAALFASGMAAASAVLLALKPGARVVAPH
                     DMYWSLRNWMIGFAANWQITLDFYADAEELAALLQRPADLVWAETPANPTWEILDIAR
                     AAELAHAAGARLVVDSTVPTPVFTRPLALGADVVMHSATKYLNGHSDVIAGVLVTRAE
                     DDLWARIKTARAAGGAVLGPFEAWLLNRGLRTLFPRVRTAAASALCIAQHFEHHPALL
                     AVRYPGLPSHPGHDIACRQMDGGFGAMLSMRVKGGEAAARRVAGAVRIFRRATSLGSV
                     ESLIEHRGPIEGPGTRCPLDLLRLSVGIEDTADLIADLEQALQKANER"
     gene            16279..17319
                     /gene="dusB"
                     /locus_tag="P5537_04725"
     CDS             16279..17319
                     /gene="dusB"
                     /locus_tag="P5537_04725"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HRV77382.1"
                     /translation="MQFAGFTLRNNLFVAPMAGVTDRPFRQLCKKLGAGVAVSEMVTS
                     NSLLYGSEKTRRRADHTGEVDPISVQIAGADPAMMGEAARYNADNGAQIIDINMGCPA
                     KKVCNVMAGSALMQDEPLVARILEAVVKAVPDTPVTLKFRTGWNRANRNAPTIARIAE
                     NSGIRAIAIHGRTRADQYMGEAEYDTIAHVKTLVKIPVIANGDIGSPQKARQVLDYTG
                     ADGVMIGRAAQGRPWIFREIEHFLATGELLPPPLVSEIHQVCREHLADLYAFYGDDRG
                     VKIARKHISWYTKGLVGSAAFRRAMNQIPDIPAQLAAVDDFFGQLAEAGTRLSYEHER
                     EAHAEYPQELAA"
     gene            17316..17552
                     /locus_tag="P5537_04730"
     CDS             17316..17552
                     /locus_tag="P5537_04730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011766619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HRV77383.1"
                     /translation="MSRSNEIADAVVRTLDQYFRDLDGEKPAAIHDMVIRNVERPMLA
                     FVLQQARGNQTVAAEMLGINRNTLRRKLTEYDLL"
     gene            17598..19187
                     /gene="purH"
                     /locus_tag="P5537_04735"
     CDS             17598..19187
                     /gene="purH"
                     /locus_tag="P5537_04735"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HRV77384.1"
                     /translation="MNVTQALISVSDKRGVLDFARELSALGIKLLSTGGTASLLREAG
                     LPVTDVSEHTGFPEMLDGRVKTLHPKVHGGILARRDLAEHMDTIAAHDIGRIDLVVVN
                     LYPFQQTVAKPDCTLEDAIENIDIGGPTMVRAAAKNHGNEQGGVGIVTDPEDYGCIVD
                     ELKANAGKLSHKTRFALAVKAFTHTARYDSAISNYLTALVTNAAGDVSLQTYPERLQL
                     AFDKVQDLRYGENPHQTAAFYRQPGAPEGGVAGYTQLQGKELSYNNIADADAAWECVK
                     AFDSSAAACVIVKHANPCGVAVAASALEAYRKAFSTDPTSAFGGIIAFNGEVDRAAAE
                     AVSAQFLEVLIAPSYTADALELLAGKKNVRVLTCPLGQPAGAFDYKRVGGGLLVQSAD
                     EARIQVADLKVVTQRAPTEAEMRDMLFAWRVAKYVKSNAIVYCKDGMTVGVGAGQMSR
                     VDSARIAKIKAENAGLQIAGCVVASDAFFPFRDGLDVLAQAGATAVIQPGGSMRDEEV
                     IAAANEQNIAMVFTGFRHFRH"
     gene            19222..20514
                     /gene="purD"
                     /locus_tag="P5537_04740"
     CDS             19222..20514
                     /gene="purD"
                     /locus_tag="P5537_04740"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HRV77385.1"
                     /translation="MKVLVIGSGGREHALAWKLAQSPKVTRVLVAPGNPGTAAEKLLQ
                     NVPVTDIKVLVELARREQVAFTVVGPEAPLAAGVVDAFRAAGLPIFGPTQAAAQLESS
                     KDFAKQFLVRHNIPTAKYRTFSDAAEAHAYIDAEGAPIVIKADGLAAGKGVVVAMTAD
                     EAHAAIDMMLLDNKMGVQYTEAGARVVIEEFMEGEEASFIVMADGKHALALATSQDHK
                     RLKDGDQGPNTGGMGAYSPAPVVTPDVHARVMREVINPTLAGMAAEGLPYTGFLYAGL
                     MIDGEGKPRVVEFNCRMGDPETQPIMMRLKTDLADLVEAAIAGKLDQTEAEWDRRFAL
                     GVVLAAAGYPESPRKGDVITNLPATEQEDVHVFHAGTALQDGQVVTAGGRVLCVTALG
                     DNVRSAQKRAYEVADGILFEGRQYRRDIGHRAIGRKTA"
     gene            20655..21563
                     /gene="hemF"
                     /locus_tag="P5537_04745"
     CDS             20655..21563
                     /gene="hemF"
                     /locus_tag="P5537_04745"
                     /EC_number="1.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004109 - coproporphyrinogen oxidase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-dependent coproporphyrinogen oxidase"
                     /protein_id="HRV77386.1"
                     /translation="MDPRSVKPWFTELQRHIVERLEAFDGQAFRSDGWDRPGGGGGLT
                     RVIEDGNFFERGGVNFSHVMGDGMPASATAHRPELAGRRFEAMGVSLVLHPRNPYCPT
                     VHLNVRCFVALAEGKDPVWWFGGGMDLTPYYPFEEDVRHFHRSCKAAVLPWGGEAEYA
                     RLKDWCDRYFFLKHRNEPRGVGGLFFDDLGADGKTDFDTAFGLTKAVGESFLGAYLPI
                     VERRRDTPYGERERDFQAYRRGRYVEFNLVFDRGTLFGLQSGGRTESILMSMPPVVKW
                     RYDWRPEAGSPEARLYEEFLVPRTWA"
     gene            complement(21643..22836)
                     /locus_tag="P5537_04750"
     CDS             complement(21643..22836)
                     /locus_tag="P5537_04750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme biosynthesis HemY N-terminal
                     domain-containing protein"
                     /protein_id="HRV77387.1"
                     /translation="MRALIWLIGIFALAVGVTMLAGVNDGYVLVVLSPWRAQVSLNLF
                     IVVLVVGVALIHLLLRMFTRTVQLPGRVARWRERRRRDKADRALHGSVTALFEGRFSE
                     ALKSASTAYSASDGSPMAALVAARAAYGLQDDTRYREWLDHAAEQGKESEVARLMTEA
                     ELAIDARQFELAAARLGQLRETGHKHIAMLRLESKVAFELGRWEELVNNVRQLRKHKA
                     LTAEQAAPALRRAHAERMRQLVGDPSALLGYWQEIPSEELADRGLIKEVLPLMARAGQ
                     AMHVRAQTETLLDEQWDSDLARLYASCANTMDDANACLHKAEAWLEKQPRDAGLLFAL
                     GQLCRRVELWGKAQSYLEASLSADPQVGTHLALAHLFETLERRDEAQRHYRAAAEKMA
                     VGALA"
     gene            complement(22847..24292)
                     /locus_tag="P5537_04755"
     CDS             complement(22847..24292)
                     /locus_tag="P5537_04755"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HRV77388.1"
                     /translation="MPETSPPVAEGDAAARSTANEGDPVAPAVSTAAVAEEQPGRSVA
                     AWWALLLALIAVGVAGWSIWQAREMRMQTGQLREEIASRISEGETIATEARGMMRQQQ
                     EVIASLQGKLGALESKVETTQGQAEALEALYQEFSRSREDGVLAEVEQAVALASQQLQ
                     IAGNVEAALIGLQEAEARLAIHDRGQLATLRRALVRDIEELRLLPVLDVSGLSLRLEL
                     MLERADTLPLGFESTLPAAAAVGAEMGPADAGGFVGWMAGVWRFAQNVAADAWSEIRT
                     LIRVERLDQADPVLLAPEQNTFLRENLKLRLLSARLALMARDGRSYGADLAQARQWVE
                     RFYDLRDERVKAALGELKELEAVKVRYEPPDLSETFSALRSVQSRAGRSSGAARASET
                     AAPAQAAPAAAATAAPAAAEAPAPAAVEAAAPAAAEAAPAAAESAAPATQPEAPAAPA
                     EAAAADAPSAAPAEQSPAPAVTDAAAPAASQ"
     gene            complement(24399..25133)
                     /locus_tag="P5537_04760"
     CDS             complement(24399..25133)
                     /locus_tag="P5537_04760"
                     /EC_number="4.2.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004373319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004852 - uroporphyrinogen-III synthase
                     activity [Evidence IEA];
                     GO_process: GO:0033014 - tetrapyrrole biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III synthase"
                     /protein_id="HRV77389.1"
                     /translation="MRPREQAESLCARIEAAGGHALRFPVIAVGPALDPAPLQAIVGR
                     LDEFDLAFFVSPNAVDHAMRAILPQRAWPARLRVATVGKGSQRVMHGWGFAEVIAPQD
                     GFDSEAVIALPEFAAEAVRGRKVLIFRGDGGRELLADTLRERGASVEYVTCYRRYCPE
                     AEPQLLLGPAARGELDGLLLTSSEGVRNLECMLGTEGLAALRAVTVFATHPRIVAQAR
                     AAGFERVVETPAGDDGLMQALESHFA"
     gene            complement(25226..26158)
                     /gene="hemC"
                     /locus_tag="P5537_04765"
     CDS             complement(25226..26158)
                     /gene="hemC"
                     /locus_tag="P5537_04765"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004418 - hydroxymethylbilane synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HRV77390.1"
                     /translation="MSQSSPERIVIATRESRLALWQAEHIKARLEALHPGCRVELLGM
                     TTRGDQILDRPLAKVGGKGLFVKELETALLDGRADIAVHSMKDVPMVMEPEFALPCIT
                     AREVPLDAFVSSRYESLADMPPGAVVGTSSLRRESQIHAQYPFLGVTSLRGNLDTRLR
                     KLDEGQYDAIILAAAGLTRLGLGERIRSVMPAEVSLPAAGQGALGIECLAARADVIGW
                     LQPLVDADTTACVLAERAVARALAGSCEVPLGAYAVMREGRLWLRGFVARPDGSTIVR
                     AEREGAPAEAEALGRALADDLRAQGAEAILAELG"
     gene            26414..29176
                     /gene="ppc"
                     /locus_tag="P5537_04770"
     CDS             26414..29176
                     /gene="ppc"
                     /locus_tag="P5537_04770"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008964 - phosphoenolpyruvate carboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0015977 - carbon fixation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HRV77391.1"
                     /translation="MNQDKDAPLRDDIRLLGRLLGDTVRDQQGEAAFGLIERIRQNSV
                     RFRRDDDIAARRELEDILDALSREQTIQVVRAFSYFSHLANIAEDQHHIRRSRAHLIA
                     GSTPREGSLAHALQRALDSGAADAAALAGFFDGALVSPVLTAHPTEVQRKSILNCETV
                     IARLLDARDRMQLTPEEAEANGEALRRAVLTLWQTRMLRTAKLSVIDEVNNGLSYFET
                     TFLRELPRLYASLEDRLAAADPALGTPELAAFVQVGSWIGGDRDGNPFVTAEVLERAL
                     AMQCAVALGHYLDELHILGSQLSLGIGLVSASDALLALAEASPDHSPHRSDEPYRRAI
                     SGIYARLAATYRSLLGHDPLRHAVAAAQPYPSAAALAEDLDVLHRSLAANGSAALTRG
                     RLRHLRRAVKVFGFHLAPLDLRQNSDVHERTVAELLERACPGTAYGSLDEDARCALLL
                     EELATARPLASPHVRYSDETEGELAIFRAARQAHLRYGKAAIRNCIISKTDDVSDLLE
                     LAVLLKEAGILRPLENALDVNIVPLFETIGDLENAAGVMERIFSIPAYRGLLASLDHT
                     QEVMLGYSDSNKDGGFLTSGWALYKAEGELVATFARHGVRLRLFHGRGGSVGRGGGPS
                     YQAILAQPEGAVQGQIRLTEQGEVIGAKYGNPEVGRRNLEVLVAATLETSLRPASASP
                     TPANFLDAMQALSDAAFAAYRGLVYETEGFERYFWESTVISEIAALNIGSRPASRKKS
                     TAIEDLRAIPWVFSWSQCRVMLPGWYGFGSAVRDFLAARPDDGLALLQRMNAEWPFFQ
                     TLLSNMDMVLSKTDLAIASRYAELVKDAALREAIFGRIRAEHQATVDAVLQITGQAEL
                     LDANPLLKRSIRNRFPYLDPLNHVQVELLRRHRDAAEAGGIDERIRLGIHISINGIAA
                     GLRNSG"
     gene            complement(29183..29989)
                     /locus_tag="P5537_04775"
     CDS             complement(29183..29989)
                     /locus_tag="P5537_04775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004373311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HRV77392.1"
                     /translation="MNEAASLAAGPLRVLVVDDEAPARARLRDLLGDVAGQQPNALVG
                     MAANGVEALRLLEDAAADVVLADIRMPVMDGVELARHLARLPEPPALVFVTAYDQYAV
                     QAFELAAVDYLLKPVRAQRLAEALERVRVRRVPPAAEALATLAAGERGHFSVAERGRI
                     LLVPVAEVLYLRAELKYVTARTAAREYVLDESLVQIEQEFPRRFLRLHRNCLVALAAV
                     AGVERAAERDGQKEGEREVEPHWEVLLRDLPERLPVSRRQWPAVRQALGI"
     gene            complement(29986..31056)
                     /locus_tag="P5537_04780"
     CDS             complement(29986..31056)
                     /locus_tag="P5537_04780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004311461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HRV77393.1"
                     /translation="MAESIKQKPPALGAPGLPDFRNLGVMLRVLLAVNLFAALTVAMR
                     LDAPGRLVEELALMAGRVELPLLLSLLLLYLGAPWLGGLPVAAGRVGVLALAGLAAVA
                     ASLLAAVPVAEWWRPLGWAGLATALCLAYFDWRSRRLSPALAEARLIALTARMRPHFF
                     FNCLNGVLGVIRSEPRRAEQALEELAELFRALMQDGRERVSLAEEVELAERYLGLERL
                     RLGERLMVRWEFGEDGPEHESGRGEAGGTGRRAELLRARVPSLLLQPLLENAVYHGIE
                     PAAGAGEVVVRIARHGKELLIEVDNPVAAQGAHHVGNRMALDNIRERLMLFHDLEARL
                     EIDEADGRYRVRIRLPWKKETT"
     gene            31151..32596
                     /gene="argH"
                     /locus_tag="P5537_04785"
     CDS             31151..32596
                     /gene="argH"
                     /locus_tag="P5537_04785"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004056 - argininosuccinate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HRV77394.1"
                     /translation="MTDTTTPAAGANAPADTSAKAWSGRFSEPVSDLVKRYTASVSFD
                     QRMAAQDIRGSLAHAKMLARQGIIGARDLADIERGMAQIAGEIERGEFAWNLDDEDVH
                     LNIEKRLTALVGDAGKRLHTGRSRNDQVATDIRLWLRDAIDRILALIAEFQARLLDVA
                     ETHAGTPMPGFTHLQVAQPVTFGHHLMAYFEMSRRDAERFADCRRRVNRLPLGAAALA
                     GTSYPIDREFVAAELGFDEVCFNSLDAVSDRDFAIEFCSASALLMTHLSRLSEELILW
                     MSPRVGFIDLADRFCTGSSIMPQKKNPDVPELVRGKTGRVNGSLVALLTLMKGQPLAY
                     NKDNQEDKEPLFDTADTVIDTLRIYADMITGIKVKAEAMRGALSQGYATATDLADYLV
                     KKGLPFRDAHEAVALAVRAAEVKGCDLPQFTLDELRIAMAHVPGAAERLADDVFGVLT
                     VEGSLASRRHVGGTAPEQVRAAVARARLGRG"
     gene            32613..33908
                     /locus_tag="P5537_04790"
     CDS             32613..33908
                     /locus_tag="P5537_04790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HRV77395.1"
                     /translation="MSAAAAERIGKYEVLRRIGMGATSSVHLAWDPFRQVEVAIKRLR
                     REILADPQRGRLLRQLFLNEAALAGKLNHPHIVRIHDALVTDEDAWLVMDHVPGGTLE
                     DIATPATLAPFERVIEIVFKATRALDYAFHQGITHRDIKPANILLMVSGGSDIRISDF
                     GAALHSARETTQIAGVGSPAYMSPQQVREVPLDHRTDIYSLGVVTFQLLTGHLPFEQE
                     NSYSLLYSIAHDTPPPPSELRPDVPEALDAIVRRATEKDIERRYQSWSEFSHDLALAF
                     RNRSLALAPDRLGDTGKFGALRTMRFFRRFADAELWEVIGLSRFDRALAGTVIIKEGE
                     RGDAICFVLAGEARVSKQGRLLEVLNPGDCFGEIAVFSTASGLRSASVEAAADTELVT
                     IRARALERASETLRMHFYQAFLEVLATRLSLASARIANL"
     gene            33905..34828
                     /locus_tag="P5537_04795"
     CDS             33905..34828
                     /locus_tag="P5537_04795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004311466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HRV77396.1"
                     /translation="MNEPASLNPALPAVEATLRTALGEHLRIVSADPVGGGSIHTALR
                     LQDASGARFFAKLAPAAQAPMFEAEADGLAAIAASGSLRTPAVIALGADDAHAFLVLE
                     WLDLQPLTSATDGARFAEALVALHRNVGEHFGWPRDNFIGRTPQANAERDNWARFFVE
                     QRLRPQFARARAQGFDVELQRQADRLLDRVPALFLDYRPPESLLHGDLWHGNAAVLAD
                     GTPVVFDPAVHRGDRESDLAMSELFGGFPAAFYAAYRCAWPLHEDYEQRKPLYSLYHV
                     LNHLNLFGRAYLRESLRLATRLNEELGRRRE"
     gene            35056..35625
                     /locus_tag="P5537_04800"
     CDS             35056..35625
                     /locus_tag="P5537_04800"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77397.1"
                     /translation="MSNSLPENSVERRRKVLKGALAASGVVTMGYSGSALASFNCIQK
                     TTLEAPFNGRQLVQVIPEAYLGWKWQSITVSADGDADGSHTGWFNYLGVNYSVALNKL
                     GSAWSATSNPEQASTTPPISPTLVPMFLLVLYDTSGSGYSPATPSPYVAGAAATPGGN
                     LPAELPQPITDSCHASLNPGTSGGGTSGG"
     gene            35633..35917
                     /locus_tag="P5537_04805"
     CDS             35633..35917
                     /locus_tag="P5537_04805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004376190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77398.1"
                     /translation="MQATVAPSPLRWLEDYCLSMDGQFVFLDPVSWQTHLLTEGAALV
                     LREAALAIEEARFDAFRDEVVEAGGWPPALEQLANTLNSLHHHPGGRAHG"
     gene            35914..36786
                     /locus_tag="P5537_04810"
     CDS             35914..36786
                     /locus_tag="P5537_04810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004376188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HprK-related kinase A"
                     /protein_id="HRV77399.1"
                     /translation="MIEATPYRVLDVGAAKLALHSPIECLHADLDRVYPHLPGTTDSG
                     FADVRVSLLPGSPLRLRGRQVSLWSEGERPFEPYPIHSALPLFEWGSNYLLSQRLNAY
                     LLLHAGVVARDDLALILPASPGSGKTTLTCALNLAGWRFLSDEFAVIDPDTGEVLPMV
                     RPAPLKNRSIAVIGERDAAVLGPLYPGTRKGDVAHFVPDRDSTLARHRRARPRAVMFP
                     RFEAGARLHCKPLDSATAVMRLGLNSFNYRALGPVGFHAAVELARRTKAWELHYGDLD
                     EAIACIETLFASLP"
     gene            36783..37886
                     /locus_tag="P5537_04815"
     CDS             36783..37886
                     /locus_tag="P5537_04815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004376187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HRV77400.1"
                     /translation="MSPRASAQTALLLRALHAPIELDEPGWDSLLRRARASGLHARLA
                     AAQAATPGLPDVVRRHFLSATRIAAYRRKLMEAELFQLAALCDTGFPVVLLKGAAYAL
                     QRRRMATGRFVSDVDLLVPAAHLRTMEQALRAAGWRSEALSPYDERYYRDWSHETPPL
                     RFPGHSLELDLHHAITPVTGSLAFDPAPLFARAEPIAGTPFHALATEDQVLHACVHCF
                     HDGDLALRVREVVDIDGLLRELAGQAGFWDRLLARAAELGLQRPLWYGLHFARAWLDC
                     PVPGAVLAALPPPAAPLRRIMDTLVALTMLPGDLDGPPSPGVRLARAAMLARYHRLRM
                     PAHLLLPHLVRKTLLRLRASVAAKKEAPDAGAP"
     gene            complement(37911..38234)
                     /gene="grxD"
                     /locus_tag="P5537_04820"
     CDS             complement(37911..38234)
                     /gene="grxD"
                     /locus_tag="P5537_04820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004376185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Grx4 family monothiol glutaredoxin"
                     /protein_id="HRV77401.1"
                     /translation="MDIQDVIRDQVTNNAVVLYMKGTPQFPQCGFSSTAVQILKGCGV
                     REVLAVNVLADPEIRQGIKDFSNWPTIPQLYVKGEFVGGSDIMREMYDSGELQQMLKD
                     AGVAE"
     gene            complement(38299..39168)
                     /gene="prmC"
                     /locus_tag="P5537_04825"
     CDS             complement(38299..39168)
                     /gene="prmC"
                     /locus_tag="P5537_04825"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004311476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HRV77402.1"
                     /translation="MSPAAPSADATDIAGALAWARARIDQMDARVLLRHVLQCPAARL
                     VAWPEQTLATEDWAEYRALVERRAAGEPVAYLTGTREFYGREFLVTPAVLIPRPETEL
                     LVELALAHFPARRGLRVLDLGTGSGALAVTLALELEAAEVVALDRSREALWVAMANAA
                     RLGASVSFVQSDWFGALGDEHFELIVSNPPYVAAGDPHLEQGDVRFEPRGALAAGPQG
                     LDDLAEIIAGAPARLVDGGWLFLEHGYDQAASARGLLADAGFAAIASWADLAGIERVS
                     GGRWLGRKTRESR"
     gene            complement(39165..40247)
                     /gene="prfA"
                     /locus_tag="P5537_04830"
     CDS             complement(39165..40247)
                     /gene="prfA"
                     /locus_tag="P5537_04830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004311477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HRV77403.1"
                     /translation="MKQSIRDKLEHLANRLEELDRTLASEDGARDMNVFRELSRERAE
                     IEPVVALYREHRQAEADCATARELLADPEMRELGELELADGEARIGALEAELQRALLP
                     RDPNDERNLFLEIRAGTGGDEAALFAGDLLRMYTRYAERQRWKVEIVSASESDLGGYK
                     EVIARVVGNGAYSRLKFESGGHRVQRIPVTETQGRIHTSACTVAVLPEADEVEAVDIN
                     PADLRIDTFRASGAGGQHINKTDSAVRITHIPTGIVVECQDDRSQHRNKAQAMAVLAA
                     RLYDARVRAQQSAEAAQRKSLVGSGDRSERIRTYNFPQGRVTDHRINLTLYKLDAVMQ
                     GELDEIVDALVLEHQAELLAALGEEA"
     gene            complement(40305..41561)
                     /gene="hemA"
                     /locus_tag="P5537_04835"
     CDS             complement(40305..41561)
                     /gene="hemA"
                     /locus_tag="P5537_04835"
                     /EC_number="1.2.1.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004311478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008883 - glutamyl-tRNA reductase activity
                     [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA reductase"
                     /protein_id="HRV77404.1"
                     /translation="MQLFALGLNHHTAPLAIRERVAFQPERMGQALHDLAHTDSVREA
                     AILSTCNRTELYFAAEQPQHAADWLARFHRLALAEVSPYLYSYPQRDAIRHVFRVASG
                     LDSMVIGEPQILGQVKDAARYAEEAGTLGVLLHKLFQNTFAVAKEVRSTTAIGANTVS
                     MAAAAVHLTERIFERVSDQHVLFIGAGEMIELCAAHFGGARPKSMTVANRTEERAKAL
                     ADRFGASTMRIDQIGDALPRFDVVVSCTAAPLPIVGLGMVERAVKARRHRPMVMVDLA
                     VPRDIEPEISELDDIFLYTVDDLAQVVEAGMESRQQAVIEAEQIIITRVDGFLHWMSA
                     RETVPVIRSLREHAESLRQAELERAVRLLAKGEDPQRVLEALSHGLTNKLMHGPTRFL
                     NQAEGEHKVEAGRVVRELFNLSRDPH"
BASE COUNT         6191 a        15367 c        14039 g         6149 t
ORIGIN      
        1 cggtgatcac ttcgttgttg acgaccgcga cgatgcggtc gacctcgacc gcgcgtggcg
       61 cagcgtgtcc aggcagcgcg agcgtggcgg ccgccaggcc gatagcgatg gcgacgcggg
      121 tgcgggagag gagttgtttc atgtcgttgg gagatgaatg cgcgggatca gcctcagtct
      181 tcaccgaaga cgcggttggc cgaggagtcg ttgatcttgc catagccggg aacgctgcgc
      241 ttgatgaggc tgagcgggtt cgagccgatc ccggcgaggt cgttcagttc cagctgcacg
      301 aagatggcgt tggtgacgtc gtcctcgtcg atcgcgaagc gatgcaccgc ggtccggaac
      361 acccagcagc cgccgtcgta ctcgatgccg gcgaccgcct cggtgatgcg gtcgtccttg
      421 agcgagtggg tgacgcgacc gacaccgtac cagttgcgcg cgagcggcca ctgcccggag
      481 acgtcgatgt ccttgaggcc cacgatgtcg tcgtcgacgc gcaggttggg cgcatagcgg
      541 tagctcaggt tgagcgtgcg cgcgaagccg ggctggtagc gcacgctggc gttgaggcgc
      601 tcggtgcggc tggtctcggt gttgtactgc gcgtaggagt ccaccgtcac cgtgctggtg
      661 acgcgtccgc cgaggccggc gagaatctcg ttgccggtgc cggcacggcg cagctcgtcc
      721 tcgttgtaga gatagacttc ctggtccgag aagtagtagc gctggccgat cagcgcgcgc
      781 aggcgctcga ccccggtctc ggcatcgatg aagcgcgtgg tgaccgccgc ggtgaggtcg
      841 ttggcgtcgc cgatgcggtc gctgcccgaa taccggttct cggcgaagat ctgcgcgaag
      901 ccgacgtcga agcggttgct gtcgaagagg gggatgtcgt cttggttacg gctcgggacg
      961 cgcaggtaga agagccgtgg ctccagcgtc tgcaggtagt ccttgccgaa gtagtgcgac
     1021 tcgcgctcga agaacaggcc ggagtcgagc gagacgatcg ggaccgagcg tgtgatcgaa
     1081 tcgggcttgc ccgccttggg cacggcacgg tcgatgtcgt agctggtgta atgcacgccc
     1141 gccttgggcg tcacgaacca ggccgcgccc tgcatcggca acgagagctg agggtaggcg
     1201 acgaagcgcg aggcctcgtc gcggtccgtc tcgcgatggg caaagcgcac gaactcggtc
     1261 tcgagcagtc cggccatccc gccggcaagg tcggcgcgtg cggcatcgag gcgcagctgc
     1321 ggcaggcggc gataaggctc gacgttgcgc acatccggat ccggattcag ggtctggtag
     1381 cgctgcgcca gcgcggaggc ggtccaccat ccgcccgcgt agatcaagcg tccctcgcgc
     1441 agcaggttca cccgcgaggc cacgccgatg ctcgacgaga gatcctcgaa gtaggcatcg
     1501 tcggagaccg cattgaggtc tagcgtgcca tagaagttgg gcgcgaagcg atgctggtgc
     1561 tggatcgagc cgagcctgcg ctcctcgccg gtgaccttgt cgttcggcat ccactcgagg
     1621 cgggtcgtgc cctggtagtc ctcgcctaga tagcgcagct cgccgccgaa ctggacgccg
     1681 cggcgggtca tgatgcgtgg cgccagggtg gcgtcgtagt tgggtgcgat gttccagtaa
     1741 taaggctggg tgaagtccac cccggtcttg ttcgacgagc cgaaggtggg cggcagcagg
     1801 ccggactggc gctgtccgct gagcgggaac tcggcccagg gcatccagaa gatcggcgta
     1861 tccatgaaca cgatcgagct gccgcgcgcg gtgccgacct cgcggtcgta gtcgagctcg
     1921 agctcgcgcg ccctgatgta ccagtccgga tcctgcgggc tgcaggtggt ccacgtcgcg
     1981 ttggcgaggc ggtactggtt ctcgccctcc aggcgcagca ggtctgcctc gccgctgccg
     2041 gccacagtgc gcggggcgtc gccggcgagc gcgggcggac gcgcccgcga gagctcgtag
     2101 gtcggtgtct cgaagctgcc gacacggtcg cccaccacca gcgtggcctt cggcccgcgg
     2161 atcgtgtcgc caccccggct cagcaccacg tcaccctcgg cgagcacctc gtcggtcggc
     2221 tcgcggtagg tgacgcgctc cgcggtcagc acggtgtcgt cgcgctggag ctcggcctca
     2281 ccctcggcga ccagctcgac cccgcgctcg ccatggatgc gcagcgcgct gaccgcggtc
     2341 tcgcccggcg cgagcgcggg gcgctcggcc gcgggcgggg cggcaggcgg agcggcagtg
     2401 gcccgtgcga cgtccttggt ggcggtggcg gtcacgggcg gcgtcggcgt cgcggcaggc
     2461 tgtggcgtcg gcgcagccac cggcgccgga ccgggagcgg gaactggagc gagagcggga
     2521 acggacatgg gctccggagc gggcgccttc gaggccggcg cagcggaggc cggggtcacg
     2581 gcgcgcgcag gcgtggccgt cggggccgga cgcagcagat cgggcgccac ctggagcgtc
     2641 ggcagggatt gcgcgaaagc ggcacccgac aggcccagca gaagcagcgg aatcagacga
     2701 atgcgcgtag tcggaagcat gcggatcgag cccttgccgt cgttcgcgat gcgcgtgcgc
     2761 ccacccgaac caccgtattg ataaactcgc ggattctaca cgaacccctg cggagatccg
     2821 gtttgcatcg cctagaacaa ctcaggacct ggctcgccgc caccctgccc ggccagtcct
     2881 tcgaactcgc cccggcctcg gcggacgcca gcttccgccg ctacttccgc gccaccttcg
     2941 ccgacggcag cccctcgcgc gtggtcatgg acgccccgcc cgaaaaggag gacgtacgcc
     3001 cctggctgca cgtggccggg ctcttcggcg ccgccggcgc ccatgtgccc gaggtgctcg
     3061 cgcaggacct cgaccaaggc ttcctgctgc tctccgacct cggctcgacg acctacctgc
     3121 aagcgctgaa ggcgcacgac gatccgcagc aagccgcccg gaccgcacat cacctgtacg
     3181 cggacgcgct cggcgcgctc gccgccatcc agtgcgccag ccgccccagc gtgctgcccg
     3241 agtacgatcg cgcgctgctg ctgcgcgagc tgcagctctt ccccgagtgg tacatcgccc
     3301 gccacaaggg cgtcaccctc accgaggccg agaccgcgat gctgaacacc gcgttcgagc
     3361 gcatcctcgc ggtgaacctc gccgagccgc aggtcttcgt gcatcgcgac taccactcgc
     3421 gcaacctgat gctgctcgag cccgccgagg gccgcggcgc caaccccggc atcatcgact
     3481 tccaggacgc cgtctacggc ccgatcagct acgacctcgt gtcgctgttc aaggacgcct
     3541 acatccgctg ggacgaggag ttcatcctcg acctgctgat ccgctactgg gagaccgcga
     3601 agaagctcgg cctgccggtg cgcgcggagt tcgccgactt ccatcgcgac ttcgagtgga
     3661 tgggcgtgca gcgccacatc aaggtgctcg gcatcttcgc ccgcctgtac caccgcgacg
     3721 gcaaggacgg ctacctcgcc gacatgccgc tggtgatgga ctacctgcgc cgggcctgca
     3781 agcgctggcg cgacctcggc ccgctgctca agctgctcga tcgcctcgag cccgagaacg
     3841 tccaggtcgg ctacaccttc tgatggcaca gatccgcgcg atgatcctcg ccgccggtcg
     3901 tggcgagcgc atgcgcccgc tcaccgacca cacccccaag ccgctgctgt cggtgggcgg
     3961 caagcccctg atcgtatggc acatcgagcg cctgcgcgcg tccggcttcc gcgagctcgt
     4021 gatcaaccac gcccacctcg gccaccggct cgaagaagcg ctcggcgacg gcacggcctt
     4081 cggcgtccgc atcgcgtggt cgcccgaggc cagcgcactg gagaccgccg gcggcatccg
     4141 ccacgccctg ccgctgctcg gcgaccagcc cttcgtcgtg gtcaacggcg atgtgttctg
     4201 cgacgccgac ttcacgtccc tgcgcgccgc cgccgaaggc ctgcacgccg acggcccgct
     4261 cgcccacctg ctgctggtgg acaaccccga gcaccacccg gaaggtgact tccacctcga
     4321 tgccgccggc ctgctccacg ccgaaggcgc cccacggctc accttctccg ggctcggcgc
     4381 ctaccatccc gccctgttcg ccgccctcgc cgacgacacc cccgccaaac tcgcccccct
     4441 gctgcgcgcg gcgatgaacg cgggccaggt caccggccgg caccacgccg ggcgctggat
     4501 cgacgttggc accccgcggc gcctggcgga cctcgactgc gagctccaac acaagaggcc
     4561 ctcttgaaca ccgataaagc caagcgcctg atcgagaccg tgctcgatca agccagacgc
     4621 atccgcccgg ccgtggtccc cgccctggcc gtgctcgtcc tcgcgctcgc ttggacggcc
     4681 gtcagccacc tcgtcggcga ggtgtcgtat gccgaggtcg cggcggcact cgccgcgacg
     4741 ccggaccggg cgctcgccat cgcgctcggc tgcaccctgc tcagcttcgt cgccctgatg
     4801 gtgtacgacc tcggcgcgct cgacttcatc gaccgcaagg tcccgcgcaa cgtcgttgcg
     4861 ctgacctcgt tctgcgccta ctcggtgggc aacacggtcg gcttcgggcc gctgaccgcc
     4921 ggcgcgatcc gctaccgctt ctacacgccc tacggcctag agcccgacga ggtcgcccgc
     4981 atcgtcgcct tcgtcaccgc cgccttcgcg atcgggctgg cggcgacggc ggccatcggc
     5041 ctgctcgtcg ccgccgatga actggccatg ctgtcggtcg cgccgttcgt gctgcagctg
     5101 atcggcggcg gcatgctggc cgccttcgtg gcgctctgcc tggccgctgg agagggcagg
     5161 acggtgagcc tgttcggctc tcctgcgcgc ctgccctcgt ggcgccagat ggtccgccag
     5221 ctggtcgcga ccatcgtcga catcggcgcc tcggccaccg tgctgtgggt gctgctgccc
     5281 gccggcagca tcgacctgcc ggccttcgtc gcgatctacg cggtcgccgt cggcctcggc
     5341 gtggtgagcc acgtgccggc cggcctgggg gtgttcgaga cggtgatcgt cgccgcgctg
     5401 agcggacgcc tgccgatcga ccagatcctg agcgcactca tcctctaccg cgtgatctac
     5461 cacctggtgc cgctgatcct ggcggtgctg ctgatcactg ggctggagct gcgcaaggcg
     5521 gcccggacgc cgctgatggc cgcggccctg aaggccgggc accgcctggc gccccccttg
     5581 atcggcgcat tcaccctggt gctcggcgcg gtgctggtgt tctcgggggt caccccggcg
     5641 agcgaggagg ccctggacgt gctgagcgac gtcgtgccgc tgccgctgct cgaaggcgcc
     5701 cacttcctcg gcagcgtgct cggcatggcc ttgctgatca tagcgcgcgg gctggtgtac
     5761 cgcctcgacg gcgcctggtg gctggcggtg atcgtcgttc cgctgtcggc catcctggcc
     5821 ttcttcaagg gcctggccct cggcgaggcc ctcatgttga cggccctgtt cgcggccctg
     5881 ctcgcctcgc ggcgcgcctt ctcgcgccac gcctcgctac tccatcaggc gatggcgccg
     5941 ggctggctcg ccgcgatggg cgtgctgctg gtgacggcgg tcgcgatcct gctgttcgtc
     6001 tacaaggacg tggattacag ccactcgctg tggtggcagt tcgagttcta cagcgaggca
     6061 ccgcgcagcc tgcgggcgct gatcggcatc acgctcaccg ccggcctggg cgcatggtgg
     6121 acgctgatga agccggtcgg ggtgcgctcg gccctgccgg acgaagaagc gctcgagcgc
     6181 gcccgccgga tcgtcgccgc ccaagcccac gtcgacgcgg gcctggtcgc catgggcgac
     6241 aagcgtctgc tgttttccga ggatggccgc gccttcatca tgtacgcgat ccaggggcgt
     6301 tcctgggtcg ccctgtccga tccggtcggc ccgcgcgaga cctggccgga gctggtgtgg
     6361 aacttcgccg aactggcccg tcatgccggc ggtcgtgcgg tcttctacca ggtcgccccc
     6421 gaatcgctcg gcctctacgc ggatgccggc ctgatggcgt tcaagctcgg cgaggaggcg
     6481 cgcgtccgac tctccgagtt cgacctcaag ggcggcaagc gcgccagcct gcgacaatcg
     6541 ctcaaccgcg ccgagcgcat gggcctgagc ttcgagatcc ttgccggacc ggcgctggac
     6601 gcctgcatgg acgagctctc cgcactctcg ggcgcgtggc tcgcgcagca caaggcgcgc
     6661 gagaagcgct tctcgctcgg cgccttcgac ccggcctacg tgcgccgcca gcccgtcgcc
     6721 ctgctgcgcc aggcagggcg cgtcgtggcc ttcgccaacg tgctgctcac cgacctcaag
     6781 caggaggcca ccgtcgacat gatgcgcttt tccgccgacg cgcccaacgg cgcgatggag
     6841 gcgctgctgc tgcacctgat cctgcacttc cagcgcgaag gctacgaatg gttcctgctc
     6901 ggcatggcac cgctgtccgg cctgtcggcg agcgcggccg cgccgatctg gcaccgcgtc
     6961 ggcaggacgg tgttcgagca cggcgaacgc ttctacaact tcagcggcct gcgcgccttc
     7021 aaggccaagt tcctgcccga gtggcagccc cgctatcttg cggtggcggg tggcatcaac
     7081 cccatgctcg cgctggcgga catcaccgtg ctgatcagcg gcgggctcaa gggagtgatc
     7141 ggcaaatgac cctgccccat cgattcctcg cgtccctcgc cctggccgcc atgctgtccg
     7201 caggcgcgcc gggcacgtcc gccgcggatc ccgagatgac gatcggcgcg ccgctgaaga
     7261 tcctccccgc cacgccgccc accggcgccg tggtgctgtt ctcggacgcg gacggctggg
     7321 acggccccga gcgcggcgcg gcggaggcgc tggcgaagca gggcctcgtg gtgatcggca
     7381 tcgacctgga aggcgtgatg cgacgcatgc gggcgcgcca cgacgactgc agcatcctga
     7441 tcggcgagat cgaggcggtc agccacgaac tccagcgcca gacgggcgcc catgcctacc
     7501 atttcccggt gctggcgggg gtcggcgaag gcgggacgat ggcgctcgcg gtcgccgacc
     7561 aggctgcggc cgcgaccctc gccggagcgg tcgcggtcga cccgctgccc gcagccgcac
     7621 tgcgccgggc actgtgcggc cacgacggcc ggccgaccga cggcaccgca aggctgatgc
     7681 cgccgcccct gcccttctcg gtggaattga tcgccagcac ggacgcgggc caagccgcac
     7741 acacgctcgt cgcccggctc gcggcggggc ggcacgacgt gcaggtcacc gacagccccg
     7801 aaaagcccgc cgccgcgctg ctggccggag tcggtcgcgc cgggcatcca cgccaggacg
     7861 acgcgctcgg cgacctgccg ctgatcgaac tccccgcact cggcccgggc acgggcgcct
     7921 tcgccatcct ctactcgggc gacggcggct ggcgggacct cgacaaggac gtcgccgcgc
     7981 tgctgcaacg cgagggcttg ccggtggtag gcgtggacgt gctgcgctac ttctggtcgc
     8041 agcgctcgcc cgaacagggc gcgcgcgatc tcgcccgcat catcgacgcc tacgccaggc
     8101 ggtggaaggc cacgcgcgtc gtgctgatcg gctactcctt cggcgcggac gtccttcccg
     8161 cgctctacaa ccgcctgccg gccgacatga agggtcgcgt cgcgcagatc tcgctgctcg
     8221 ggttcgcaac ccgcgcgagc ttcgaggtca cggtctccga atggctcggc cacgcgcgcg
     8281 aggacagcgt gccgaccctg cccgaagcgc tgcgcatcga tcagcgcctg ctgcagtgct
     8341 tccagggcga cgaagacgac gaggccgctt gcacgggcct gggcgccggg gcggagatca
     8401 tccgcaccag cggcggacac catttcgacg gcgactacga agccctcgcc cgccgcatcc
     8461 tgcacggcgt ggagcggcgt tcgccgcatt aggcgcaagc ggcccgcggc gtcgccgcgt
     8521 gacataattc cgcccatgaa cgcacccggc accgccccca tggacacccc ccccttccgc
     8581 gcccgccgcg cccgcctgct gcagcgcatg caggccgccg gcggcggcgt cgccatcctg
     8641 cccaccgccc ccgagcgcgt gcgcaaccgc gacgcccact acgcctaccg ccacgacagc
     8701 tacttctact acctcaccgc cttccgcgaa cccgaggccg tggtcgtgct ggtggcgggc
     8761 aaggagacga agcagatcct cttctgccgc gagaagaacg aggaacgcga gatctgggac
     8821 ggctaccgct ggggccccga cgcggcgcgc gaggccttcg gcttcgacga ggcgtggacc
     8881 atcggcgacc tcgagaagcg cctccccgac accctcgccg accagcccct gctgtggacc
     8941 agcctcggct acgacaacga ctgggacgcg aaggtactcg gcgcgctcaa cgccgtgcgc
     9001 gacaaggccc gcaccggcct caccccgccg cactcggtgc gcgacctgcg cgccgaactc
     9061 gacgagatgc gtctcgtcaa ggacgcttcc gagctcgcca ccatgcgccg cgccgcccgc
     9121 atctcggccg acgcccacgg ccgcgccatg cgcgccaccc gcccggggcg cttcgaatac
     9181 gagatcgagg ccgagctgct gcacgccttc cgcgccgctg gcagccaggc ccccgcctac
     9241 accagcatcg tcgccggcgg cgccaacgcc tgcgtgctgc actacgtcga caacgaccag
     9301 cgcctgaagg acggcgacct gctgctgatc gacgccggct gcgagctcga cggctacgcg
     9361 tccgacatca cccgcagctt cccggtgaac ggccgcttct ccggcgcgca gcgcgacgtg
     9421 tatgagctcg tgctcgccgc ccaggtcgcc gcgcgcgagg ccacccgccc cggcgcgcac
     9481 tggaaccagc cgcacgacgc cgcggtgaag gtgctcgccc agggcatgct cgacctcggc
     9541 ctcctccagg gcagcctcga cggcgtgctc gagagcggcg actaccgccg cttctacatg
     9601 caccgcaccg gccactggct gggcatggac gtgcacgacg ccggcgaata caagctcggt
     9661 ggcgagtggc ggccgctcgt cgagggcatg gtgctgacca tcgagccggg ctgctacatc
     9721 cgccccgccg acgacgtgcc cgaggccttc tggaacatcg gcatccgcat cgaggacgac
     9781 gcggtggtca cggccggagg ctgcgagctg atcaccgagg acgtgcccaa ggcgatcacg
     9841 gagatcgagg ccctgatgcg agacacgcgc catgcctgag aacgctcccg agcgcgtcca
     9901 tgacctgctg atcgtcggcg ccggcccggt cggcctcgcg ctggcgctcg cgctcaagga
     9961 cgccggcctc gacatcgtgc tcgccgacgc gcgcgcccgt gaagcggtga cgaaggaccc
    10021 gcgcgacctc gcgctcgccc acggcacccg gctcacgctg cagcgcctcg gcgtctggaa
    10081 cacgctgccg cgcaccgcga tcgagcacat ccatatctcg catcagggcg ggctcggccg
    10141 caccctgatc gacgccgccg aacacggtct gcccgcgctc ggctacgtcg cctccgccgg
    10201 cgcgctcgcc gcggccctgc gcgaggcggt cgatgcagcg ggcatccccg tgttcgacga
    10261 gaccgagatc accaacctgg ccgcgggcga ggaagacgtg atcgccagcc tcgccggcgc
    10321 cggccgcccc gcgccgacgc tgcgcgcgcg gctcgccgcc tgcgccgagg gcggcctgcg
    10381 cgcgggcgac cccaacgtgg tcgagcacga ctacggccag cacgcactga tcgccgacgt
    10441 gcaggtcgcc ggcggccacc gccacaccgc cttcgagcgc ttcaccccgc agggcccggt
    10501 ggcgctgctg cccaagggcg acggctacgc gctggtgcat gtcgcccatc ccgacaccgc
    10561 cgacgagttg cttgcgctcg acgatgccgc ctacctcgcc cgcctgcagg cccacatcgg
    10621 cggccgcgcg cggctcaccg gcgtcggccc gcgcctgcgc tatccgctgg tgctgcgcta
    10681 ccggcgctcg accatcgcgc agcgcacagt gtggctcggc aatgcggcgc agaccctgca
    10741 tccggtcgcc ggccagggct tcaacctggc gctgcgcgat gtgtgggcgc tggccgacgc
    10801 gctgctgcgt gcgcgcgagg cggctcggcg gggtgcggcc gacactgcac cgggcccctt
    10861 cgacgccggc gccgctaccg tcctcgcacg ctatgcgaac gcccgcggcc tggaccgcct
    10921 cggcacgatc cgcttcaccg acaccctggt gcgggtgttc agcaacgact tcgccccgct
    10981 gcgccacgcg cgcggcgccg cgctgctcgc gctcgacctg atcccgccgc tgcgcaactt
    11041 cctcgcgcgc cgcatgatgt tcggcgcccg cgcgtggccc tgagccgccg gcgtggcgca
    11101 cgtcggccga cggtctagac tgagagcgtg aggcgcaggt tgcgccaaac ccgggagggg
    11161 gcatggagtc gaatcgaccg cggcggcgcg ggcgagttca cccaggcgca gcagtcgcaa
    11221 tgcgcgaaca agcggcttga ttcgaggccg caatggacac gtccgcctcc accggtaact
    11281 ccgacgacct gcgtgacaag ttccgtcaag gcctgcgcga gctctcgccc gcctatttcg
    11341 gcatggcgat ggcgaccggc atcgtttccc tttccgcgca catgcagggc tggaagtggc
    11401 tcgcgaccac gctgttctgg atcaatgcca gcctctatgg cgtactctgg ctcctgctgc
    11461 tgctgcggat cgcctggcat ccaggcgcgg tgcgcaccga tctgctcgat catctgcgcg
    11521 cgcccggctt cttcaccacg gtggcggcca gcggtgtgct cggcacgcaa tgcctggtgg
    11581 ttgcggacag cctggggggc gcgatcacgc tctggtgcgt ggcgctggtg ctctggctgc
    11641 tgctgaccta cacgatcttc accatgctgg tggtcaaggc ggaaaaacct cctctcgacc
    11701 aaggcatcaa cggcggctgg ctgctcgcgg tcgtcgcgac gcaggcggtc gcggtgctgg
    11761 gcaccctgat cgcgacccgc atcccgcagc cctatcggct cgaactcaat ttcttcgcgc
    11821 tgtcgatgtg gctgtggggc ggcatgctct acatctggat gatgtcgctg atcttctacc
    11881 gctacacctt cttccgcttc tcgcccgccg atctgtcgcc gccctactgg atcaacatgg
    11941 gcgcgatggc gatctcgacg ctggccggca gtcagctgat cctgaacgcc ccgcacgccc
    12001 ccttcctcga gtcgctgctg cccttcatca agggcttcac ggtgttctac tgggcgaccg
    12061 gaagctggtg gatcccgatg ctgatcgtgc tcgcggcatg gcgccacggc gtgatgcgct
    12121 tcccgctgcg ctacgacccc ctgtactggg gtgccgtgtt cccgatcggc atgtactcgg
    12181 cgtgcacact gcgcctgcac gaggcgatgg ccctgccctt cctcgaccgt attccgccgg
    12241 tcttcctcgt catcgccctg tgcgcgtggg cactcgcatt caccgggctc gtactcgacc
    12301 tgctcgcccg cgtgcgcgcc ccggcacgcg cgacgcgggc ttgagacacg acgatcagaa
    12361 cgccggcacc accgcgccct ggtacttgtc ggcgaggaac tgcttcacct ccggcgagtt
    12421 cagcgcggcg gcgagcttcc tgatcgccgg actgttcgcg ttgtcgtcgc gcgccaccag
    12481 caggttggcg tagggcgagc tggcgtcctc gatgaagagc gagtccttca gcgggttcag
    12541 cttggcctcg atcgcgtagt tggtgttgat caccgccagg tcgacctggt tcagcacgcg
    12601 cggcagggtc gcggcctcga gctcgcggat cctgagcttc ctcgggttct cggcgatgtc
    12661 cttctgggtg gccgagatgt tgttcagatc cttgagcttc agcagcccgt tcttcgccat
    12721 cagcagcagc gcgcggccgg agttggacgg gtcgttcggg atcgccacgg tcgcgccctc
    12781 ggggatgtcc gccaccgcct tgtgcttgcc ggagtaggca cccagcggct cgacgtgcac
    12841 cttggtcacc acggtctgga tgtcgttctt ctgcttctgc ttgaacgcgt cgaggtaggg
    12901 ctggtgcagg aagaagttgc cgtcgacgcg cttctcgttg gtctgcatcg agggctgcac
    12961 atagtcggtg aacaccttca cctcgagctc cacgccttcc ttggccagca tcggcttgac
    13021 gaactcgagg atctcggcgt gcggcaccgg ggtggcggcg atgaccaggc ggtcggcggc
    13081 gaccgcggcg ttgccggcag cgagggcgag cgtgccgaaa gcggcggcga acagtttgcg
    13141 cagggtaaac gacatcgttg aagtctcctt cgtggggatc acttgcgggt gaaatacagc
    13201 accaggcggt cgcccgagta ctggatgatc tggacgagca cgaccagcag ggcgacggtg
    13261 atcaccatca cctcggtctg gaagcgctga tagccgaaac ggatcgcgag gtcgccgagg
    13321 ccaccgccgc cgatcacgcc ggacatcgca gcataggaca tcaaggtgat cgccgtcacc
    13381 gtgaccgcgg cgatcagccc gggcagggcc tcgggcagca gcgcgccgaa gatgatgcgc
    13441 gaggtgcgga tgcccatcgc ctggcaggcc tcgatcacgc cgcggtcgac ctcgcgcagc
    13501 acgttctcga ccaggcgcgc gaagaagggc gcggtgccca ccaccagcgg cgggatcgcg
    13561 ccctcgacgc cgagcgaggt gccgatcagg atcaccgtga ccgggatcat cacgatcagc
    13621 aggatcagga agggcaccga gcgcagcacg ttgaccacga acgagagcac cgtatagacg
    13681 aggccctgct cgagcagctg gcgcttggcg gtgacgaaca gcaggattcc cagcggcagg
    13741 ccgagcagga tggtgaagaa cagcgacacc ccggtcatga ccagggtctc ccaggtcgcg
    13801 atccagatgt cgctccagtc gatgacggac aggtccatta ctgcagcacc tcgtggtgga
    13861 tctggtggcg gtcgagctcg gcgaacaccg cgcggatgtc gtcctcgccg ccctcgagct
    13921 cgagcagcag ctggccgaag ggcacgtcct tgatgctgga gacctcgccc tgcaggatcg
    13981 tgacctgcac cctggcgccg gccatgatgc ggctgaggat gggctggtag gtcacgtcgc
    14041 cgatgtaggt cagccgcacc agcgtgccgc gcagcttgtc cttcatgtag gcgtgcgccg
    14101 gatcgaagct cgccgcggcg agcgcgtcgc tctgcgccac catgctgcgg gtgaccgggt
    14161 gctgcgggtg caggaacacg tcggccaccc ggccagactc gacgatgcgc ccgccgtcga
    14221 tcaccgcgac gcggtcgcag atggtgcgga tgacctgcat ctcgtgggta atgagcacga
    14281 tggtgaggcc gagctggcgg ttgatgtcga gcagcaggcg caggatggac tgcgtggtct
    14341 cggggtcgag cgccgaggtg gcctcgtcgc agagcaggat ctgcggacgg ttcgcgagcg
    14401 cgcgcgcgat gcccacgcgc tgcttctgcc cgcccgagag ctgcgacggg tacttgtggc
    14461 cgtgctcgga cagcccgacc aggtccagca actccctgac ccgcgccgcg cgctcggcgg
    14521 cgttgccgtg cccggtggcc ttgagcggcc agtcgatgtt gtcggcgacg gtcttggcgt
    14581 tgagcaggtt gaaatgctgg aagatcatgc cgacgcggcg gcgcagcgcg tacaggccct
    14641 cgctgtcgag ttgcgtgatg tcctcgccgt cgatcagcac gcgcccggcc gaggggcgct
    14701 cgagcaggtt cagggtgcgg atcagcgtgc tcttgccggc acccgagcgg ccgatgatgc
    14761 cgaacacttc gccggcgcca atctcgaggt cgatgtcggc gagcgcctcc acctcgcggc
    14821 cgtcggcggc acggtaggtc ttgcgcaggt tttcgatgcg gatcaaggcg gctttccggg
    14881 ctggaaaaaa acccgtgatt ttacccgcag gccggactcg acaccactac ggggaacttg
    14941 taggctcgcc ggcaccctgg cagccgcccc ctcatcctca ccgctccgcc cgaaggaccg
    15001 cgcctcatgc agcacgacga cacgctctcc cccgccaccc tcgccgccca gggcctgggc
    15061 accatcccga tgccgcaccg cgacatcgtg ccgccgatcc atatggcgac caccttcgag
    15121 cgcgcagagg acggcagcct gcccggcggg cgcatctacg cgcgcgacgc cagcccggca
    15181 tacgaccccg ccgaagccct cttgtgcagg ctcgaaggcg gcgccgccgc ggcgctgttc
    15241 gcctccggca tggccgcggc ctccgcggtg ctgctggcct tgaagcccgg cgcgcgcgtc
    15301 gtcgccccgc acgacatgta ctggtcgctg cgcaactgga tgatcggctt cgcggccaac
    15361 tggcagatca cactggattt ctacgccgac gcagaagagc ttgccgcgct gctgcagcga
    15421 ccggccgacc tggtgtgggc agagacgccc gccaacccga cctgggagat cctcgacatc
    15481 gcgcgcgcag ccgagctcgc ccacgccgcc ggcgcccgcc tggtggtcga ctccaccgtg
    15541 ccgaccccgg tatttacccg cccgctcgcg ctcggcgccg acgtggtgat gcattcagcc
    15601 accaagtacc tcaacggcca ctccgacgtg atcgccggcg tgctggtgac gcgcgccgag
    15661 gacgacttgt gggcgcgcat caagaccgcg cgtgccgcgg gcggtgccgt gcttggcccc
    15721 ttcgaggcct ggctgctcaa ccgcggcctg cgcaccctct tcccgcgcgt gcgcaccgca
    15781 gccgcctcgg cactgtgcat cgcgcagcac ttcgagcatc acccggcgct gctcgccgta
    15841 cgctaccccg gcctgccctc tcaccccggc cacgacatcg cctgccggca gatggatggc
    15901 ggcttcggcg ccatgctgtc gatgcgggtc aaaggcggtg aagcggccgc acgccgggtc
    15961 gccggcgccg tcaggatctt ccgccgcgcc acctccctcg gctcggtcga gagcctgatc
    16021 gagcaccgcg gcccgatcga aggcccgggc acacgctgcc cgctcgacct gctgcgcctg
    16081 tcggtgggca tcgaggacac cgccgacctg atcgccgacc tcgaacaggc actgcagaaa
    16141 gcgaacgagc gctgaagtcc caaaggattt cacccccagc ccggcccacg accccgcgtc
    16201 gtcgcccgcg tggcggcgct gcgacacggg caagagtcga tagggtaaaa tgttgcgttt
    16261 tcgcctgcca ttcacgccat gcagtttgcc ggcttcacct tgcgcaacaa tctcttcgtc
    16321 gcccccatgg ccggggtgac ggaccgtcct ttccgccagt tgtgcaagaa gctcggcgca
    16381 ggcgtggccg tgtcggagat ggtcacctcc aactcgctgc tctatggcag cgagaagacc
    16441 cgccgtcgcg ccgaccacac cggcgaggtc gatccgatct cggtgcagat cgccggcgcc
    16501 gaccctgcga tgatgggcga agccgccagg tacaacgccg acaacggcgc gcagatcatc
    16561 gacatcaaca tgggctgccc ggccaagaag gtgtgcaacg tcatggccgg ctcggcgctg
    16621 atgcaggacg agcccctggt cgcgcgcatc ctcgaggcgg tggtgaaggc cgtgcccgat
    16681 accccggtca cgctcaagtt ccgcaccggc tggaaccgcg ccaacaggaa cgcccccacg
    16741 atcgcccgta tcgccgaaaa ctccggcatc cgcgccatcg ccatccacgg ccgcacgcgc
    16801 gccgaccagt acatgggcga ggccgagtac gacaccatcg cccacgtcaa gacgctggtg
    16861 aagatcccgg tgatcgccaa cggcgacatc ggcagcccgc aaaaggccag gcaggtgctc
    16921 gactacaccg gcgccgacgg cgtcatgatc gggcgcgcgg cacagggccg gccgtggatc
    16981 ttccgcgaga tcgagcactt cctcgccacc ggcgagctgc tgccgccgcc gctggtgagc
    17041 gagatccacc aggtttgccg cgagcacctc gccgacctgt acgccttcta cggcgacgat
    17101 cgcggcgtga agatcgcgcg caagcacatc tcctggtaca ccaagggcct cgtaggctcg
    17161 gcggccttcc gccgcgcgat gaaccagatc cccgacattc ccgcccagct cgccgccgtc
    17221 gacgacttct tcggccagct cgccgaggcc ggcacccgcc tgagctacga gcacgagcgc
    17281 gaggcgcacg ccgaatatcc gcaggaactc gcagcatgag ccgcagcaac gagatcgcgg
    17341 acgccgtcgt ccgcaccctc gaccagtatt tccgcgacct cgacggcgag aagccggcgg
    17401 ccatccacga catggtgatc cgcaacgtcg agcgtccgat gctggccttc gtcctccagc
    17461 aggcccgagg caaccagacc gtggccgcgg agatgctcgg catcaaccgc aacaccctgc
    17521 ggcgcaagct gaccgaatac gacctgctct gagcgggtgc atcccttttt ctccatccct
    17581 ccgcttccgg cccaacgatg aacgtgaccc aagccctgat cagcgtctcc gacaaacgcg
    17641 gcgtgctcga cttcgcccgt gagctctccg ccctcggcat caagctgctg tcgaccggcg
    17701 gcaccgccag cctgctgcgc gaggccggcc tgccggtgac cgacgtctcc gagcacaccg
    17761 gcttccccga gatgctcgac ggccgcgtca agaccctgca tccgaaggtg cacggcggca
    17821 tcctcgcccg ccgcgacctc gccgagcaca tggacaccat cgccgcgcac gacatcggcc
    17881 gcatcgacct cgtggtggtg aacctctacc ccttccagca gaccgtggcc aagcccgact
    17941 gcacgctgga agacgcgatc gagaacatcg acatcggcgg ccccaccatg gtgcgcgccg
    18001 cggccaagaa tcacggcaac gaacagggcg gcgtcggcat cgtcaccgac cccgaggact
    18061 acggctgcat cgtcgacgag ctcaaggcca acgccggcaa gctcagccac aagacccgct
    18121 tcgcgctcgc ggtgaaggcc ttcacccaca ccgcgcgcta cgactcggcg atctccaact
    18181 acctcaccgc gctggtcacc aacgcggccg gcgacgtgtc gctgcagacc taccccgagc
    18241 gcctgcagct cgccttcgac aaggtgcagg acctgcgcta cggcgaaaac ccgcaccaga
    18301 ccgcggcctt ctaccgccag cccggcgcgc ccgagggcgg cgtggccggc tacactcagc
    18361 tgcagggcaa ggaactgtcg tacaacaaca tcgccgacgc cgacgcggcg tgggagtgcg
    18421 tgaaggcctt cgacagctcg gccgccgcct gcgtcatcgt caagcacgcc aacccctgtg
    18481 gggtggccgt cgcggccagc gcgctcgagg cctacaggaa ggccttctcc accgacccga
    18541 cctcggcctt cggcggcatc atcgccttca acggcgaggt cgaccgcgcc gccgccgagg
    18601 ccgtctcggc gcagttcctc gaggtgctga tcgccccgtc ctacaccgcc gacgcgctcg
    18661 aactgctcgc cggcaagaag aacgtgcgcg tgctcacctg cccgctcggt cagcccgccg
    18721 gcgccttcga ctacaagcgc gtgggtggcg gcctgctggt gcagagcgcc gacgaggcgc
    18781 gcatccaggt cgccgacctc aaggtcgtga cccagcgtgc gccgacggaa gccgagatgc
    18841 gcgacatgct gttcgcctgg cgcgtggcca agtacgtcaa gtcaaacgcc atcgtttact
    18901 gcaaggacgg catgaccgtc ggcgtcggcg ccggccagat gagccgcgtc gactccgcac
    18961 gcatcgccaa gatcaaggcc gagaacgccg gcctgcagat cgccggctgc gtggtggctt
    19021 cggacgcctt cttccccttc cgcgacggcc tcgacgtgct cgcccaggcc ggcgccaccg
    19081 cggtgatcca gcccggcggc tcgatgcgcg acgaggaggt gatcgccgcc gccaacgagc
    19141 agaacatcgc catggtcttc accggcttcc gccacttccg ccactaagca cgaccacccc
    19201 agcagagctt cggagcagca catgaaagtc ctcgtcatcg gttccggcgg ccgcgaacac
    19261 gcgctggcct ggaaactcgc ccagtcgccc aaggttaccc gcgtgctggt cgcgccgggc
    19321 aaccccggca ccgctgccga gaagctgctg cagaacgtgc cggtcaccga catcaaggtg
    19381 ctggtcgagc tggccaggcg cgagcaggtc gccttcaccg tggtcggccc cgaggccccg
    19441 ctggccgccg gcgtggtcga tgccttccgc gccgccggcc tgccgatctt cggcccgacc
    19501 caggccgccg cccagctcga gagctccaag gacttcgcca agcagttcct cgtccgccac
    19561 aacatcccga ccgcgaagta ccgcacgttc tcggatgcgg ccgaggcgca cgcctacatc
    19621 gacgccgagg gcgcgccgat cgtgatcaag gccgacggcc tcgccgcggg caagggcgtg
    19681 gtggtggcga tgacggccga cgaggcgcac gccgcgatcg acatgatgct gctcgacaac
    19741 aagatgggag tgcagtacac cgaggcaggc gcgcgcgtcg tcatcgagga gttcatggaa
    19801 ggcgaggaag ccagcttcat cgtcatggcc gacggcaaac acgcgctcgc gctcgccacc
    19861 agccaggacc acaagcgcct caaggatggc gaccagggcc ccaacaccgg cggcatgggc
    19921 gcctactcgc ccgcgccggt ggtcaccccc gacgtgcatg cgcgcgtgat gcgcgaagtc
    19981 atcaacccga cgctggccgg catggcggcc gagggcctgc cctacaccgg cttcctctac
    20041 gccggcctga tgatcgacgg cgagggcaag ccgcgcgtgg tcgagttcaa ctgccgcatg
    20101 ggcgaccccg agacgcagcc catcatgatg cggctgaaga ccgacctcgc cgacctcgtc
    20161 gaggccgcga tcgccggcaa gctcgaccag accgaggccg agtgggatcg tcgcttcgcg
    20221 ctcggcgtgg tgctggccgc cgccggctat cccgagagcc cgcgcaaggg cgacgtcatc
    20281 accaatctgc ctgcgaccga gcaggaggac gtgcacgtgt tccacgccgg caccgcgctg
    20341 caggacggcc aggtcgtcac cgcgggcggt cgcgtgctgt gcgtgaccgc gctcggcgac
    20401 aacgtgcgca gcgcgcagaa gcgcgcctac gaggtcgccg acggcatcct cttcgaaggc
    20461 cgccagtacc gccgcgacat cggccatcgc gcgatcggac gcaagaccgc ctgatcgccg
    20521 ggcgccgtcc aggcgccccc atcgccgtct ccacccctgc gcgagacggc ccttgcactt
    20581 gatttcgccg ccgacgccga cgctgcgccc ccatgcgctt ggcactggca cggcaacgcc
    20641 acggaggccc ccgcatggat ccacgcagcg tcaaaccctg gttcaccgag ctgcagcgcc
    20701 acatcgtcga gcgcctcgag gcctttgatg gccaggcctt ccgcagcgat ggctgggacc
    20761 gcccgggtgg cggcggcggc ctcacccggg tgatcgagga cggcaacttc ttcgagcgcg
    20821 gcggggtgaa cttctcgcac gtgatgggcg atggcatgcc cgcttcggcg accgcacacc
    20881 gcccggagct ggccggccgc cgcttcgagg ccatgggcgt gtcgctggtg ctgcatccgc
    20941 gcaatccgta ctgccccacc gtgcacctga acgtgcgctg cttcgtcgcg ctcgccgaag
    21001 gcaaggatcc ggtgtggtgg ttcggcggcg gcatggacct gacgccctac taccccttcg
    21061 aggaggacgt gcgccatttc caccgcagct gcaaggccgc ggtgctgccc tggggcggcg
    21121 aggccgaata cgcccgcctc aaggactggt gcgaccgcta cttcttcctc aagcaccgca
    21181 acgagccgcg cggcgtcggc ggactgttct tcgacgacct cggggccgac ggcaagacgg
    21241 acttcgacac cgccttcggc ctcaccaagg cggtggggga gagcttcctc ggcgcctacc
    21301 tgcccatcgt cgagcgccgc cgcgacacgc cctatggcga gcgcgagcgc gacttccagg
    21361 cctaccggcg cggccgctac gtcgagttca acctcgtctt cgaccgcggc accctgttcg
    21421 gcctgcagtc cgggggacgc accgaatcca tcctgatgtc gatgccgccg gtggtgaagt
    21481 ggcgctacga ctggcgcccg gaggccggtt cgcccgaggc caggctgtac gaagagttcc
    21541 tcgtcccgcg cacctgggcc tgatccacgg aaccgaaggt agctgcaccg ccgtagaaaa
    21601 aacggggcct cgcggccccg gttctcattg cgtctgcctt gttcaggcca gcgcgccgac
    21661 cgccatcttc tcggccgcgg cacggtagtg gcgctgcgcc tcgtcgcgac gctccagggt
    21721 ctcgaacaga tgcgcgagcg ccagatgggt gcccacctgc ggatccgcgc tgagcgaggc
    21781 ctcgaggtaa ctctgcgcct tgccccacag ttcgacccgc cggcagagct ggccgagggc
    21841 gaacagcagc cccgcgtcgc gcggctgctt ctccagccac gcttccgcct tgtgcaggca
    21901 ggcgttggcg tcgtccatcg tgttggcgca gctcgcgtag agacgcgcca gatcgctgtc
    21961 ccactgctcg tcgagcaggg tctcggtctg cgcacgcacg tgcatcgctt gcccagcgcg
    22021 cgccatcagc ggcagcacct ccttgatcag gccacgatcg gcgagttcct cggaggggat
    22081 ctcctgccag tacccgagca aggcggacgg gtcgccgacg agctggcgca tgcgctcggc
    22141 gtgggcacgg cgcagcgcgg gcgcggcctg ctcggcggtc aaagccttgt gcttgcgcag
    22201 ttggcggacg ttgttcacca gctcctccca gcgcccgagc tcgaacgcga ccttgctctc
    22261 gaggcgcagc atcgcgatgt gcttgtgccc ggtctcgcgc agctgcccga ggcgggccgc
    22321 cgcgagctcg aactggcggg catcgatcgc gagctccgcc tcggtcatca ggcgggcgac
    22381 ctcgctctcc ttgccctgct cggcagcgtg atccagccac tcgcgatagc gcgtgtcgtc
    22441 ctgcagaccg taggccgcgc gcgccgcgac cagcgcggcc atcggcgagc catcgctcgc
    22501 ggagtaggcg gtcgacgccg acttcagcgc ctcggagaaa cgcccctcga agagggcggt
    22561 caccgagccg tgaagcgcgc ggtcagcctt gtcgcgacgg cggcgttcgc gccagcgcgc
    22621 cacccggccg ggcagctgca ccgtacgggt gaacatccgc agcagcaggt ggatcagggc
    22681 cacgcccacc accagcacca cgatgaagag gttcagtgaa acctgggctc gccacggtga
    22741 cagcacgacg agcacgtagc cgtcattcac gccggccagc atggtcacgc cgacggcgag
    22801 ggcgaagatg ccgatcagcc agatcagtgc gcgcatcgtt cggccctcac tggctcgccg
    22861 ccggggcggc agcatcggtc acggcaggag caggcgactg ctcggcgggc gcagcggacg
    22921 gcgcgtcggc agcggcggcc tcggccggcg ccgccggggc ttcgggctgg gtggcgggcg
    22981 ccgcgctctc ggctgcggcg ggcgctgcct cggccgcggc cggggcagcg gcctcgacgg
    23041 cggccggggc gggggcttcg gcagccgccg gcgccgcggt tgcagcggcg gcgggcgcgg
    23101 cctgggccgg cgccgcggtc tcgctcgcac gcgcagcgcc actgctgcgg ccggcgcgcg
    23161 actgcacgct gcgcagcgca ctgaaggtct cgctcagatc gggcggctcg tagcgcacct
    23221 tcaccgcctc gagttccttc agctcgccga gcgcggcctt gacgcgctcg tcgcgcagat
    23281 cgtagaagcg ctccacccac tggcgggcct gggcgaggtc ggcgccgtag ctgcggccgt
    23341 cgcgcgccat cagcgcgaga cgcgcgctca acagccggag cttgaggttc tcgcgcagga
    23401 aggtgttctg ctcgggcgcg agcagcaccg ggtccgcctg gtcgagacgc tcgacgcgga
    23461 tcagggtgcg gatctcgctc caggcgtcgg ccgccacgtt ctgggcgaag cgccacacgc
    23521 cggccatcca gcccacgaag ccgcctgcat ccgcaggccc catctccgcg cccaccgcgg
    23581 ccgcggccgg caaggtgctc tcgaagccga gcggcagcgt gtcggcgcgc tcgagcatca
    23641 gttcgaggcg caggctgagg ccggagacgt ccagcaccgg cagcaggcgc agttcctcga
    23701 tgtcgcgcac cagcgcgcgg cgaagggtgg cgagctggcc gcgatcatgg atcgccagcc
    23761 gggcctcggc ctcctgcagg ccgatcagcg cggcctcgac gtttccggcg atctgcagct
    23821 gctgcgacgc cagcgcgacc gcctgctcca cctcggcgag cacgccgtcc tcgcggctgc
    23881 gcgagaactc ctggtacagg gcctccagcg cctcggcctg gccctgagtg gtctcgacct
    23941 tggactcgag cgcaccgagc ttgccctgca gcgaggcgat gacttcctgc tgctgccgca
    24001 tcatgccgcg tgcctcggtg gcgatggtct cgccctcgga aatacggctg gcgatctcct
    24061 cgcgcagctg gcccgtctgc atgcgcatct cgcgcgcctg ccagatcgac cagcccgcca
    24121 cgccgacggc gatcagcgcc agcagcagcg cccaccacgc ggccacgctg cggccgggct
    24181 gctcctcggc tacggccgcg gtcgacacgg cgggggcgac cggatcgccc tcgttcgcgg
    24241 tgctgcgggc cgcagcatcg ccctcggcaa cgggcggcga cgtctcgggc acgccgacct
    24301 cctcgatgac gggtcgggtc tcctccgggg ccggcgatgc ggacgtcggc ggcggcggct
    24361 gggtcagagc gggattttct tgtctcatgg ttccacgtct aggcaaagtg gctttctagg
    24421 gcctgcatca aaccgtcatc tccggccggc gtctcgacca cccgttcgaa accggccgct
    24481 cgcgcctgcg cgacgatgcg cgggtgcgtg gcaaacaccg tcacggcgcg cagggcggca
    24541 agcccctccg tgccgagcat gcattccaga ttgcgtacgc cctcgctgct ggtcagcagc
    24601 aggccgtcga gctcgccacg cgccgccggg ccgagcagga gctgcggctc ggcctcggga
    24661 cagtagcgtc ggtaacaggt gacatattcc acgctcgcgc cgcgttcgcg caaggtgtcg
    24721 gcaagcagct cgcgaccgcc gtcgccgcgg aagatcagta ccttgcgccc gcgcaccgcc
    24781 tcggcggcga actcgggcag cgcgatcacg gcttcgctgt cgaagccgtc ctgcggtgcg
    24841 atgacctcgg caaagcccca gccgtgcatc acgcgctggc tgcccttgcc cacggtggcg
    24901 acccgcaggc gggcaggcca ggcgcgctgc ggcaggatcg cgcgcatggc gtggtcgacc
    24961 gcgttggggc tgacgaagaa ggcgagatcg aactcgtcga ggcggccgac gatggcctgc
    25021 agcggcgccg gatcgagcgc cggaccgacc gcgatcaccg ggaagcgcag cgcatgcccg
    25081 cccgcggcct cgatccgcgc gcacagactc tcggcctgct ctcgcggtcg cattacgacg
    25141 aggctacgcc cggcgagagg gcgcagggac tggagatcgg aagctgctgc cggggtcgtc
    25201 accgcgcgcc tcccttgccg tccgttcagc cgagctcggc gaggatcgct tccgcgccct
    25261 gcgcccgcag gtcgtcggcg agcgcacggc cgagcgcctc ggcctcggcg ggcgcgccct
    25321 cgcgctcggc gcgcacgatg gtgctgccgt cggggcgggc aacgaagcca cgcagccaca
    25381 gccggccctc gcgcatcacc gcataggcgc ccagcggcac ctcgcagctg ccggcaagcg
    25441 cacgggcgac cgcacgctcg gcgaggacgc aggcggtggt gtcggcatcg accagcggct
    25501 gcagccagcc gatcacgtcg gcgcgcgcgg caaggcattc gatgccgagc gccccctgcc
    25561 cggccgcggg caacgagacc tcggccggca tcaccgagcg gatgcgctcg cccaggccga
    25621 gccgggtaag gcccgcagcg gcgaggatga tggcgtcgta ctggccctcg tcgagcttgc
    25681 gcaggcgggt atcgaggttg ccgcgcaggc tggtcacgcc caggaagggg tactgcgcgt
    25741 ggatctgcga ttcgcggcgc agcgaggagg tgccgaccac ggcgcccggg ggcatgtcgg
    25801 cgaggctctc gtagcgactg gagacgaagg cgtcgagcgg gacctcgcgc gcggtgatgc
    25861 agggcagcgc gaactcgggc tccatcacca tcggcacgtc cttcatcgaa tgcaccgcga
    25921 tgtcggcgcg gccgtcgagc agcgcggtct cgagttcctt gacgaacagg cctttgccgc
    25981 cgaccttggc gagcggacgg tcgaggatct ggtcgccacg cgtggtcatg cccagcagct
    26041 cgacccggca gccgggatgg agcgcctcga ggcgggcctt gatgtgttcg gcctgccaca
    26101 gggcgagacg gctttcacgg gttgcgatga cgatgcgctc ggggctgctt tgactcacga
    26161 tcgggattca cctggaaaac gggggcacag gtgcggaggc gccaggcgcc gggatgatgc
    26221 atcgcaacat gacagaatgc tgaatgcgtc cgcacgactc ggcgcattct agcacggggg
    26281 ccggccgcgc cgcctcccac gggcagccgg caggaaggag ggcaagctcc cggatcgacc
    26341 cgaaacgggc aggaaagcga gcggcttgcg gtaagctcca ccctcccctc ccatcgaatt
    26401 ccgaaacgaa agaatgaacc aggacaagga cgcccccctc cgcgacgaca tccgcctgct
    26461 cggccgcctg ctcggcgaca ccgtgcgcga ccaacagggc gaggccgcat tcggcctcat
    26521 cgaacgcatc cggcagaact cggtgcgctt ccgccgcgac gacgacatcg ccgcgcgccg
    26581 cgagctggag gacatcctcg acgcgctgtc gcgcgagcag accatccagg tcgtgcgcgc
    26641 cttcagctat ttctcccatc tcgccaacat cgccgaggac cagcaccaca tccggcgcag
    26701 ccgcgcgcac ctgatcgccg gctcgacgcc gcgcgagggc agcctggcgc acgccttgca
    26761 gcgcgcgctc gacagcggcg cggcagacgc cgcggcgctg gccggtttct tcgacggcgc
    26821 gctggtgtcg ccggtgctca ccgcccaccc caccgaggtg caacgcaaga gcatcctcaa
    26881 ctgcgagacc gtgatcgcac ggctgctgga tgcgcgcgac cgcatgcagc tcacccccga
    26941 ggaggccgag gccaacggcg aggcgctgcg ccgcgcggtg ctgacgctgt ggcagacgcg
    27001 catgctgcgc accgccaagc tgtcggtgat cgacgaggtc aacaacggcc tgtcgtactt
    27061 cgagaccacc ttcctgcgcg agctgccgcg gctctacgcc agcctggagg accgcctcgc
    27121 cgccgccgac ccggcgctcg gcacgcccga gctggccgcc ttcgtgcagg tggggagctg
    27181 gatcggcggc gaccgcgacg gcaacccctt cgtcaccgcc gaggtgctcg aacgggcgct
    27241 cgccatgcag tgcgcggtcg cgctcgggca ctacctcgac gagctgcaca tcctcggctc
    27301 ccagctctcg ctcggcatcg gcctggtgtc cgcctccgac gccctgctcg cgctcgccga
    27361 ggcctcgccg gaccactcgc cgcatcgcag cgacgagccc taccggcgcg cgatctcggg
    27421 gatctacgcg cgcctggccg ccacctaccg cagcctgctc ggccacgacc cgctgcgcca
    27481 cgcggtcgcc gccgcgcagc cctacccgag cgcggccgcg ctcgccgagg acctcgacgt
    27541 gctgcaccgc tcgctcgccg ccaacggctc ggccgcgctc acgcgcgggc ggctgcgcca
    27601 cctgcggcgc gcggtgaagg tgttcggctt ccacctcgcc ccgctcgacc tgcggcagaa
    27661 ctccgacgtg cacgagcgca cggtcgccga gctgctcgag cgcgcctgcc ccggcaccgc
    27721 gtatggcagc ctcgacgagg acgcgcgctg cgcactgctg ctcgaagagc tcgccaccgc
    27781 gcgtccgctc gcctcgccgc acgtgcgcta ttcggacgag accgagggcg agctggcgat
    27841 cttccgcgcg gcgcgccagg cccacctgcg ctacggcaag gcggcgatcc gcaactgcat
    27901 catctccaag accgacgacg tctccgacct cctcgagctc gcggtgctgc tgaaggaagc
    27961 cggcatcctg cgcccgctgg agaacgcgct cgacgtcaac atcgtgccgc tcttcgagac
    28021 catcggcgac ctcgagaacg ccgccggcgt catggagcgc atcttctcga tccccgccta
    28081 ccgcggcctg ctcgcgtcgc tcgatcacac ccaggaggtc atgctcggct actccgacag
    28141 caacaaggac ggtggcttcc tgacctcggg ctgggcgctg tacaaggccg agggcgagct
    28201 ggtcgccacc ttcgcccgcc acggcgtgcg cctgcgcctg ttccacggcc gcggcggctc
    28261 ggtgggtcgc ggcggcgggc ccagctacca ggccatcctc gcccagcccg agggcgcggt
    28321 gcaggggcag atccgcctca ccgaacaggg cgaggtgatc ggcgccaaat atggcaaccc
    28381 ggaagtcggc cggcgcaacc tggaggtgct cgtggccgcc acgctcgaga ccagcctgcg
    28441 cccggccagc gccagcccga ccccggccaa cttcctcgac gccatgcagg ccctgtcgga
    28501 cgcagccttc gccgcctacc gcggcctggt gtacgagacc gagggcttcg agcgctattt
    28561 ctgggaatcc accgtgatca gcgagatcgc cgcgctcaac atcggcagcc gcccggcctc
    28621 gcgcaagaaa agcaccgcga tcgaggacct gcgcgccatc ccctgggtgt tcagctggtc
    28681 gcaatgccgg gtgatgctgc ccggctggta cggcttcggc agcgcggtgc gggacttcct
    28741 cgccgcacgc cccgacgatg gcctggcgct cctgcagcgc atgaacgccg agtggccgtt
    28801 cttccagacc ctgctgtcga acatggacat ggtgctctcc aagaccgacc tcgcgatcgc
    28861 cagccgctac gccgagctgg tcaaggacgc ggcattgcgc gaggcgatct tcggccgcat
    28921 ccgcgccgag caccaggcca cggtcgacgc ggtgctgcag atcaccggcc aggccgagct
    28981 gctcgacgcc aacccgctgc tcaagcgttc gatccgcaac cgcttcccct acctcgaccc
    29041 gctcaaccac gtccaggtcg agttgctgcg ccgccaccgc gacgccgccg aggcgggcgg
    29101 catcgacgag cgcatccgcc tcggcatcca catctccatc aacggcatcg ccgcggggct
    29161 gcgcaacagc ggctgagccg gcctagatgc cgagcgcctg ccgcaccgcc ggccactgcc
    29221 ggcggctcac cggcaggcgc tcgggcaggt cgcgcagcag cacctcccag tgcggctcga
    29281 cctcgcgctc gccctctttc tgtccatcgc gctccgccgc ccgttcgacg ccggccaccg
    29341 cggcgagcgc gaccaggcag ttgcggtgca ggcgcaggaa gcgacgcggg aactcctgct
    29401 cgatctgcac cagcgattcg tcgagcacgt actcgcgcgc ggcagtgcgc gcggtgacgt
    29461 acttgagctc ggcacgcaga tagagcacct cggccaccgg caccagcagg atgcggccgc
    29521 gctcggctac gctgaagtgg ccgcgctcgc ccgccgccag cgtggcgagc gcctccgcgg
    29581 ccggcggcac gcggcgcacc cgcacgcgct cgagcgcctc ggcgaggcgc tgcgcgcgca
    29641 ccggcttgag caggtagtcc accgcggcaa gctcgaaggc ctgcaccgcg tactggtcgt
    29701 aggcggtcac gaacaccagc gccggcggct cgggcaggcg ggcgaggtgg cgcgcgagct
    29761 ccaccccgtc catcaccggc atgcggatgt cggccaggac cacgtccgcc gccgcatcct
    29821 cgagcagccg cagggcctcg acgccgttgg ccgccatgcc gacgagcgcg ttcggctgct
    29881 gcccggcgac gtcgccgagc aggtcgcgca ggcgtgcccg cgccggcgcc tcgtcgtcga
    29941 cgacgagaac gcgcagcggc ccggcggcaa gcgatgcggc ctcgttcatg ttgtctcctt
    30001 tttccagggc aggcggatgc gcacccggta gcgcccgtcc gcctcgtcga tctcgagccg
    30061 cgcctcgagg tcgtggaaca gcatcaggcg ctcgcggatg ttgtccagcg ccatgcggtt
    30121 gccgacatgg tgcgccccct gcgcggcgac cgggttgtcc acctcgatga gaagctcctt
    30181 gccgtgccgg gcgatgcgga cgaccacctc gccagccccg gcggcgggtt cgatgccgtg
    30241 gtagacggca ttctcgagca agggctgaag cagcaacgag gggacgcggg cgcgcagcag
    30301 ctcggcccgc ctgccggtcc cgccggcctc cccgcgccca ctctcgtgtt ccggcccgtc
    30361 ctcaccgaac tcccagcgca ccatcaggcg ctcgccaagc cgcaggcgct ccaggcccag
    30421 gtagcgttcg gcgagctcga cctcctcggc caggctcacg cgctcgcggc cgtcctgcat
    30481 cagcgcgcgg aacagctccg cgagctcctc cagcgcctgc tcggcacggc gcggctcgga
    30541 gcggatcacg ccgagcacac cgttcaggca gttgaagaag aagtgcgggc gcatgcgcgc
    30601 ggtgagggcg atcagccgcg cctcggcgag tgccggcgac aggcgcctgc tgcgccagtc
    30661 gaaatacgcc agacagagcg cggtggcgag cccggcccag cccagcggcc gccaccactc
    30721 ggccacgggc acggcggcca gcaggctggc ggcaaccgcc gccaggccgg cgagcgcgag
    30781 caccccgaca cgcccggccg cgaccggcag cccgcccagc cagggcgcgc cgaggtagag
    30841 caggagcagg ctcagcagca gcggcagctc gacccgcccg gccatcagcg cgagttcctc
    30901 gacgagccgg ccgggtgcat cgagccgcat cgccacggtg agcgcggcga agaggttcac
    30961 cgccagcagc acgcgcagca tgacccccag gttgcggaag tcgggcaggc cgggcgcgcc
    31021 gagcgcgggg ggcttttgct ttatactttc ggccatcctt gcgcaccgcc cgggcggcgc
    31081 cctctccctt gatcgtccca tgccgggccg gcacagcagg tccggccctc ccgtttccaa
    31141 cgccccgatt atgacagaca ccacgacgcc ggccgccggc gccaacgcac ccgcagacac
    31201 gagcgccaag gcctggtccg gccgcttctc cgaacccgtc tccgatctgg tcaagcgcta
    31261 caccgccagc gtgtccttcg accagcgcat ggccgcgcag gacatccgcg gctcgctcgc
    31321 gcacgcgaag atgctggccc gccagggcat catcggcgcc cgggacctcg ccgacatcga
    31381 gcgcggcatg gcgcagatcg ccggcgagat cgagcgcggc gagttcgcct ggaacctcga
    31441 tgacgaggac gtccacctca acatcgagaa gcgcctcacc gcgctcgtgg gcgacgccgg
    31501 caagcgcctg cacaccggcc gcagccgcaa cgaccaggtc gccaccgaca tccgcctgtg
    31561 gctgcgcgac gcgatcgacc gcatcctcgc gctcattgcc gagttccagg cccgcctgct
    31621 cgatgtcgcc gaaacccacg ccggcacgcc catgcccggt ttcacccacc tgcaggtggc
    31681 gcagccggtc accttcggcc accacctgat ggcctacttc gagatgagcc gacgcgacgc
    31741 cgagcgcttc gccgactgcc gccgccgcgt caaccgcctg ccgctgggcg cggcggcact
    31801 cgccggcacc agctacccga tcgaccgcga gttcgtcgct gccgagctcg gcttcgacga
    31861 ggtctgcttc aactcgctgg acgccgtcag cgatcgtgac ttcgccatcg agttctgctc
    31921 cgccagcgcg ctgctgatga cccacctgtc gcgcctgtcc gaggagctga tcctgtggat
    31981 gagcccgcgc gtgggcttca tcgacctcgc cgaccgcttc tgcaccggct cttcgatcat
    32041 gccgcagaag aagaaccccg acgtgcccga gttggtgcgc ggcaagaccg gccgcgtcaa
    32101 tggcagcctg gtcgcgctgc tgacgctgat gaagggccag ccgctggcct acaacaagga
    32161 caaccaggaa gacaaggagc cgctgttcga caccgccgac acggtcatcg acacgctgcg
    32221 catctacgcc gacatgatca ccggcatcaa ggtcaaggcc gaggccatgc gcggcgcgct
    32281 cagccagggc tacgccaccg ccaccgacct cgccgactac ctggtcaaga agggcctgcc
    32341 cttccgcgac gcgcacgagg cggtggcgct ggcggtgcgt gcggccgagg tcaagggctg
    32401 cgacctgccg caattcaccc tggacgaact gcgcatcgcc atggcccatg tgcccggcgc
    32461 ggccgagcgc ctggccgacg acgtcttcgg cgtgctcacc gtcgagggtt cgctcgcctc
    32521 gcgcaggcac gtcggcggca ccgcgcccga gcaggtgcgt gccgcggtgg cgcgcgcccg
    32581 cctcggccgg ggctgatccc ggctcgacgc ccgtgagcgc agcggcggcc gaacgcatcg
    32641 gcaagtacga ggtcctccgc cgcatcggca tgggcgccac gagcagcgtc cacctcgcct
    32701 gggacccctt ccgccaggtc gaggtggcga tcaagcgcct gcgccgcgag atcctcgccg
    32761 atccacagcg cgggcgcctg ctgcgccagc tcttcctcaa cgaggctgcg ctcgccggca
    32821 agctgaacca cccgcacatc gtgcgcatcc atgacgcgct ggtcaccgac gaggatgcct
    32881 ggctggtcat ggaccacgtg ccgggcggca cgctcgagga catcgcgacg ccggcgacgc
    32941 tggcgccctt cgagcgcgtc atcgagatcg tcttcaaggc cacacgcgcg ctcgactacg
    33001 ccttccacca aggcatcacc caccgcgaca tcaagcccgc caacatcctg ctgatggtct
    33061 ccggcggcag cgacatccgc atctccgatt tcggtgccgc gctgcactcg gcacgcgaga
    33121 ccacgcagat cgccggcgtc ggctcgcccg cctacatgtc gccgcagcag gtgcgcgagg
    33181 tgccgctcga ccaccgcacc gacatctact cgctcggcgt ggtgacgttc cagctcctca
    33241 ccggccacct gcccttcgag caggagaaca gctacagcct gctctacagc atcgcccacg
    33301 acaccccgcc gccgccctcc gagctgcgcc ccgatgttcc cgaggcgctc gacgcgatcg
    33361 tacgccgcgc caccgagaag gacatcgagc gccgctacca gagctggagc gagttctccc
    33421 acgacctcgc gctcgccttc cgcaaccgca gcctcgcgct tgcccccgac cgcctcggcg
    33481 acaccggcaa gttcggggcc ctgcgcacga tgcgtttctt ccgccgcttc gccgacgccg
    33541 agctgtggga ggtgatcggg ctgtcgcgct tcgaccgcgc gctcgccggc accgtgatca
    33601 tcaaggaagg cgagcgcggc gacgccatct gcttcgtgct cgccggcgag gcgcgggtga
    33661 gcaagcaggg ccgcctgctc gaagtactca accccggcga ctgcttcggc gagatcgcgg
    33721 tgttctccac cgcctcaggg ttgcgctcgg cctcggtcga ggccgccgcc gacaccgagc
    33781 tggtgacgat ccgcgcacgc gccctcgaac gtgccagcga gaccctgcgc atgcacttct
    33841 accaggcctt cctcgaggtg ctggcaacgc ggctctcgct cgccagcgcc cgcatcgcga
    33901 acctatgaac gaaccggcca gccttaatcc cgccctgccc gccgtcgagg ccaccctgcg
    33961 caccgcactg ggcgagcacc tgcgcatcgt ctcggcagac ccggtcggcg gcggcagcat
    34021 ccacaccgcg ctacgtctcc aggacgccag cggcgcgcgc ttcttcgcca agctcgcccc
    34081 tgccgcccag gcgccgatgt tcgaggccga ggccgacggc ctcgccgcga tcgcggccag
    34141 cggcagcctg cgcacccctg cggtgatcgc cctgggcgcg gacgacgcgc acgccttcct
    34201 ggtgctggaa tggctcgatc tgcagccgct caccagcgcg accgacggcg cccgcttcgc
    34261 cgaggcgctg gtggcgctgc accgcaacgt cggcgagcac ttcggctggc cgcgcgacaa
    34321 cttcatcggg cgcaccccgc aggcgaacgc cgagcgcgac aactgggcgc gcttcttcgt
    34381 cgagcagcgc ctgcgcccgc agttcgcgcg cgcccgcgcg cagggcttcg acgtcgagct
    34441 gcagcgccag gccgatcgcc tgctcgaccg cgtccctgcg ctcttcctcg actaccgccc
    34501 gcccgagagc ctgctccacg gcgacctctg gcacggcaac gcggcggttc tcgccgacgg
    34561 cacgccggtg gtcttcgacc ccgcggttca ccgcggcgac cgcgaatccg acctcgccat
    34621 gagcgagctc ttcggcggct tccccgccgc cttctacgct gcctaccgct gcgcctggcc
    34681 gctgcacgag gactacgagc agcgcaagcc gctgtacagc ctctatcacg tgctcaacca
    34741 cctcaacctg ttcggccgag cgtacctgcg cgagtccttg cgcctggcga cgcggctcaa
    34801 cgaggaactg gggcggcggc gggagtgagt cctgtcgcac tggagcgcgg cggcgtgtcg
    34861 gaatttctta cactgcgccc ttttcgcgat ccgtcccgcc gagccatagg cacgccaaat
    34921 caggcacttg ccgtgtcgat tgaactccgg gcgtgaaatt tgctactaaa ggcctgaagt
    34981 atcggaaagt cggctgaagt tgcgcggcta taatctgaac gtagtcgcca tcgcgcgcat
    35041 tgaagaggtt tccccatgtc caactccctg cccgaaaatt cggtcgaacg ccgccgaaag
    35101 gtcctcaagg gtgcgctcgc cgcatccggc gtggtgacca tgggctacag cgggtcggcg
    35161 ctggcgtcgt tcaactgcat ccagaagacg accctggagg cgccgttcaa tggccgccag
    35221 ctcgtccagg tgatcccgga ggcgtacctc ggctggaagt ggcagtcgat caccgtcagc
    35281 gcagacggcg acgccgacgg ttcgcataca gggtggttca attacctcgg ggtgaattac
    35341 agcgttgcgt tgaacaagct tggtagtgcc tggagcgcga ccagcaaccc ggagcaggcc
    35401 tcgacgacgc ccccgatcag cccgacgctt gtcccgatgt tcttgctggt tctgtacgac
    35461 acgtcgggct cgggctactc cccagcgacc ccctccccct acgttgccgg tgccgctgcc
    35521 accccgggcg gtaacctgcc cgcggaattg ccgcaaccca tcaccgactc ctgccacgcc
    35581 tcgctcaacc cgggcacgag cggtggcgga accagcggag gctgaagcgg gggtgcaagc
    35641 aaccgtcgcc ccctcgccgc tgcgctggtt ggaagactac tgcctgtcca tggacgggca
    35701 gttcgttttt ctggaccccg tctcctggca gacccacctt ctcaccgaag gcgccgcgct
    35761 ggtgttgcgc gaggccgcgc tggcgatcga ggaggcgcgc ttcgacgcct tccgggacga
    35821 ggtcgtcgag gccggcggct ggccgcccgc gctggagcag ctcgccaata cgctgaacag
    35881 cctgcaccac catccgggcg gacgcgcgca cggatgatcg aggccacgcc ctatcgggtg
    35941 ctcgacgtcg gcgcggcgaa gctcgcgctg cattcgccga tcgagtgcct gcacgccgac
    36001 ctcgaccgcg tctatccgca tctccccggg accaccgaca gcggcttcgc cgacgtgcgc
    36061 gtgtcgctgc tgcccggctc gcccctgcgc ctgcgcggcc gccaggtgag cctgtggtcc
    36121 gagggcgagc gccccttcga accctacccg atccacagcg ccctgccgct cttcgagtgg
    36181 ggcagcaact acctgctgag ccagcgcctg aacgcctacc tgctgctgca cgcgggcgtg
    36241 gtggcccgcg acgatctggc gctgatcctg cccgcctccc ccggctcggg caagaccacg
    36301 ctcacctgcg cgctcaatct ggccgggtgg cgcttcctct ccgacgagtt cgcggtcatc
    36361 gacccggaca ccggcgaggt gctgcccatg gtccgccccg ccccgctcaa gaaccgctcg
    36421 atcgcggtga tcggcgagcg cgacgccgcg gtgctcggcc cgctctatcc gggcacacgc
    36481 aagggcgacg tcgcccactt cgtccccgac cgcgacagca cgctcgcccg gcaccgccgc
    36541 gcgcgcccgc gggcggttat gttcccgcgc ttcgaagcgg gcgcgcgcct gcactgcaaa
    36601 ccgctcgaca gcgccacggc ggtgatgcgc ctgggcttga acagcttcaa ctaccgcgcc
    36661 ctcggcccgg tcggctttca cgccgccgtc gaactcgcgc gccggacaaa ggcctgggag
    36721 ctgcactacg gcgatctcga cgaggcgatc gcctgcatcg aaaccctgtt cgcgagcctg
    36781 ccatgagccc ccgcgcatcc gcccagaccg ccttgctgct gcgcgccctg catgcgccga
    36841 tcgaactcga cgagccgggc tgggacagct tgctgcggcg cgctcgcgcc agcgggctgc
    36901 acgcgcggct ggcggcagca caggccgcca cgccggggct tcccgatgtg gtgcgccgtc
    36961 actttctctc ggccacccgg attgcggcct accggcgcaa gctgatggag gcggagctgt
    37021 tccagctcgc tgcgctgtgc gacaccggct ttccggtcgt cctgctcaag ggcgccgcct
    37081 acgccctgca gcgacgtcgc atggccaccg gccgcttcgt ctcggatgtc gatctgctcg
    37141 tcccggccgc ccatctgcgc acgatggagc aggccttgcg tgccgccggc tggcgcagcg
    37201 aagcgctttc gccctacgac gagcgctact accgtgactg gagccacgag acgccaccgc
    37261 tgcgctttcc cgggcacagc ctggagctcg acctgcacca cgccatcacc ccggtcaccg
    37321 gcagcctcgc cttcgacccc gcgccgctgt ttgcgcgcgc cgagccgatc gccggtacgc
    37381 ccttccatgc gctcgccacc gaggatcagg tcctgcacgc ctgcgtacac tgcttccacg
    37441 atggcgatct cgccctgcgc gtgcgcgaag tggtggatat cgacggcctc ctgcgcgagc
    37501 tggccggcca ggccggattc tgggaccggt tgctggcgcg cgcagccgaa ctcggcctgc
    37561 agcgcccgct ctggtatggg ctgcatttcg cccgtgcgtg gctggactgc ccggttcccg
    37621 gcgccgtcct cgccgccctg cccccgccgg cggcgccgct gcgcaggatc atggacacgc
    37681 tcgtcgcgct gacgatgctc cccggcgacc tggacggccc gccttcgccg ggcgtgcgcc
    37741 ttgcccgtgc ggcgatgctc gcgcgctacc accgcctgcg catgccggcg cacctgctgc
    37801 tgccgcatct cgtgcgcaag accctgctgc gcctgcgcgc aagcgtcgca gccaaaaaag
    37861 aagcgcccga cgcgggcgct ccctgatcct tcctgccacc gacgccgaaa tcactcggcg
    37921 acgccggcgt ccttcagcat ctgctgcagc tcgccgctgt cgtacatctc gcgcatgatg
    37981 tcactgccac cgacgaactc gcccttgacg tagagctgcg gaatggtcgg ccagttggag
    38041 aaatccttga tgccctggcg gatctcgggg tcggcgagca cattgaccgc gagcacctcg
    38101 cgcacgccgc agcccttgag gatctgcacc gcggtggagg agaagccgca ctgcgggaac
    38161 tggggcgtgc ccttcatgta gagcaccacg gcgttgttgg tgacctgatc gcggatgacg
    38221 tcctggatgt ccatgctgga aacctgaaaa agttgagtta aacagtcggg aaataatagg
    38281 ggttgggcgg cggcagcgtc aacgcgattc gcgcgttttt cgtcccagcc agcgcccgcc
    38341 cgagacacgc tcgatgccgg cgaggtctgc ccacgaggcg atcgcggcga agccggcgtc
    38401 ggcgagcaga ccacgcgccg acgcagcctg gtcgtaaccg tgctcgagaa acagccagcc
    38461 accgtccacc aggcgcgccg gcgcaccggc gatgatctcg gcgaggtcgt cgagaccctg
    38521 cggtccggcg gcgagcgcgc cgcgcggctc gaagcgcacg tcgccctgct ccaggtgcgg
    38581 gtcgcccgcg gccacatagg gcggattgga gacgatgagc tcgaagtgct cgtcgccgag
    38641 cgcgccgaac cagtcgctct gcacgaagga gacgctcgcc cccagcctgg cggcgttggc
    38701 catcgccacc cacagcgcct cgcgcgagcg gtcgagcgcg accacctcgg ccgcctcgag
    38761 ctcgagcgcc agcgtcaccg cgagcgcgcc gctgccggtg ccgaggtcga gcacgcgcag
    38821 gccgcggcgg gcgggaaagt gggcgagcgc gagctcgacc agcagctcgg tctccgggcg
    38881 cgggatcagc accgccgggg tgacgaggaa ctcgcgcccg tagaactcgc gcgtgccggt
    38941 gagataggcc accggctcgc cggcggcgcg acgttcgacg agggcgcgat attcggccca
    39001 gtcctcggtg gcgagcgtct gctcgggcca cgccaccagg cgcgcggccg ggcactgcag
    39061 cacgtggcgc agcagcacgc gcgcgtccat ctggtcgatg cgcgcgcgcg cccaggcgag
    39121 cgcgccggcg atgtcggtcg cgtcggcgga gggcgccgca gggctcatgc ctcctccccg
    39181 agcgccgcga gcagctcggc ctggtgctcg agcacgagcg cgtcgacgat ttcgtcgagc
    39241 tcgccctgca tcaccgcgtc gagcttgtag agggtgaggt tgatgcgatg gtcggtgacg
    39301 cgcccctgcg ggaagttgta ggtgcggatg cgctcggagc ggtcgccgct gcccaccagg
    39361 ctcttgcgct gcgcggcctc ggcgctctgc tgcgcgcgca ccctggcgtc gtagaggcgt
    39421 gcggcgagca ccgccatcgc ctgcgccttg ttgcggtgct gcgagcggtc gtcctggcac
    39481 tcgacgacga tgccggtcgg gatgtgcgtg atgcgcaccg ccgagtcggt cttgttgatg
    39541 tgctgaccgc ccgcccccga ggcgcggaag gtgtcgatgc gcaggtcggc ggggttgatg
    39601 tccaccgcct cgacctcgtc ggcctcgggc agcacggcga cggtgcatgc ggaggtgtgg
    39661 atgcgcccct gggtctcggt gaccgggatg cgctgcacgc ggtgaccgcc ggattcgaac
    39721 ttgagccggg agtaggcgcc gttgcccacc acgcgggcga tgacctcctt gtagccgccg
    39781 aggtcggatt cgctcgccga cacgatctcc accttccagc gctggcgctc ggcgtagcgg
    39841 gtgtacatgc gcagcaggtc gccggcgaac agcgccgcct cgtcgccgcc ggtgccggcg
    39901 cggatctcca ggaagaggtt gcgttcgtcg ttggggtcgc gcggcagcag cgcgcgctgc
    39961 agctcggcct cgagcgcccc gatgcgcgcc tcgccgtcgg cgagctcgag ctcgccgagc
    40021 tcgcgcatct cggggtcggc gagcagctcg cgcgcggtgg cgcagtcggc ctcggcctgg
    40081 cgatgctcgc ggtacagcgc caccaccggc tcgatctcgg cgcgctcgcg cgagagctcg
    40141 cggaagacgt tcatgtcgcg cgcgccgtcc tcggaggcga gcgtgcggtc gagctcttcg
    40201 agccggttgg cgaggtgttc gagtttgtcg cggatgctct gcttcatggc ggtggacgga
    40261 ggcgcgcgcg ccgcgcgcgg gcggcggccg acgcagccgt tcggctagtg ggggtcgcgg
    40321 gacaggttga agagctcgcg caccacacgg ccggcttcga ccttgtgctc gccctcggcc
    40381 tggttcagga agcgggtggg accgtgcatc agcttgttgg tgagaccgtg cgagagcgcc
    40441 tcgagcacgc gctggggatc ctcgcccttg gcgagcaggc gcaccgcgcg ctcgagctcg
    40501 gcctggcgca ggctctcggc gtgctcgcgc agcgagcgga tcaccggcac cgtctcgcgc
    40561 gccgacatcc agtgcaggaa gccgtcgacc cgggtgatga tgatctgctc ggcctcgatc
    40621 accgcctgct ggcgcgactc cattccggcc tcgaccacct gggcgaggtc gtccaccgtg
    40681 tacaggaaga tgtcgtcgag ttcggagatc tcgggctcga tgtcacgcgg cacggcgaga
    40741 tcgaccatca ccatcgggcg atggcggcgc gccttgaccg cgcgctcgac catgcccagg
    40801 ccgacgatcg gcagcggcgc ggccgtacag gagaccacca cgtcgaagcg cggcagcgcg
    40861 tcgccgatct ggtcgatgcg catggtgctg gcgccgaagc ggtccgccag ggccttggcg
    40921 cgctcctcgg tgcggttggc caccgtcatc gacttcggcc gggcgccgcc gaagtgggcg
    40981 gcgcagagct cgatcatctc gccggcgccg atgaacagca cgtgctggtc ggagacgcgc
    41041 tcgaagatgc gctcggtcag gtgcaccgcg gccgcggcca tcgacaccgt gttggcgccg
    41101 atcgcggtgg tcgagcgcac ctccttggcc accgcgaagg tattctggaa cagcttgtgc
    41161 agcagcacgc ccagggtgcc tgcctcctcg gcgtagcgcg cggcgtcctt gacctggccg
    41221 aggatctgcg gctcgccgat caccatcgag tcgagcccgc tcgctacccg gaaaacatgg
    41281 cggatggcgt cgcgctgcgg gtaggaatac aggtagggcg agacctcggc gagcgcgagg
    41341 cgatggaagc gcgccagcca gtcggccgca tgctgcggct gctcggcggc gaaatagagc
    41401 tcggtgcggt tgcaggtcga caggatcgcc gcctcgcgca ccgaatccgt gtgagccaga
    41461 tcgtgcagcg cctgccccat gcgctcgggc tggaacgcga cgcgttcgcg gatggcgagc
    41521 ggcgcggtgt ggtggttcaa gccgagggcg aagagttgca tgcgggaggg gggtgggacg
    41581 gagcgagccg gattataaca ccgcgcctgc gccccaaaat tgagccggaa cagcgacttc
    41641 tggccgcaat ttgacgccgc aaagcagatg ggccgacact cggtcggccc atcgggattc
    41701 ttggtggcca gtcgcggaat cgaaccacgg acacgcggat tttcaa
//
LOCUS       DAOTIN010000019        39488 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_1089_length_39488_cov_9.219258, whole genome shotgun sequence.
ACCESSION   DAOTIN010000019 DAOTIN010000000
VERSION     DAOTIN010000019.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 39488)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 39488)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39488
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1089_length_39488_cov_9.219258"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1362
                     /locus_tag="P5537_04840"
     CDS             <1..1362
                     /locus_tag="P5537_04840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004312594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HRV77405.1"
                     /translation="MPLPPHAPEQQPFVSIHLACYNEPPEMVIATIDSLAEMNYQNFE
                     VLILDNNTRDEALWKPLERRCAELGPRFRFFHLANWPGFKAGALNYGLKVTDPRAEVV
                     GVVDADYVVDPDWLACLVPHFDQPEVAVVQAPQAHRDWEGQPFKRMCNWEFDGFFRIG
                     MHHRNERNALIQHGTMTMVRRRALEEVGGWSEWCICEDTELGLRLIEKGYDTRYIDHI
                     LGRGLTPSGFAAIKSQRFRWAFGAMQILKAHLPHMIGRSTLNLAQRYHFLTGWFAWLG
                     DALQLVFAFGSLLWTLGILLFPKAFGLPVVSLALPIFGFMIFKAALGPILYRRTMDCP
                     WKDILGASILSVGLAHAIARGVFAGLVKKKGVFVVTPKGWRGGGALAFFNPIREEIGM
                     LVALLMGAATLVAQRGANNLETQLWVGILCLQCIPYVAAILCQVAAYMPERGATAGET
                     AAA"
     gene            complement(1499..2827)
                     /locus_tag="P5537_04845"
     CDS             complement(1499..2827)
                     /locus_tag="P5537_04845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004312596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008509 - monoatomic anion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006820 - monoatomic anion transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DASS family sodium-coupled anion symporter"
                     /protein_id="HRV77406.1"
                     /translation="MRNLNLVVAGVLFLSLQWGLDGLPDRAGAGLALLATIAWLWLTE
                     ALHVSVTALLVPVLAAASGVLAFPEALLQFADPVVFLFLGGFALAAGLQRQGLDRWMA
                     GQVLRRAGASFGRAVRWLFWLTAFLSMWISNTATAAMMLPLALGLLAPLPLDEHRRTW
                     MYVLLGVAFSANIGGIGTLVGSPPNAIAAAAVGMGFAEWMSWGLPLVLVMMPLMEIGL
                     RLVLRPRLDVVVTPPPPPAGWTPAQRRMLALFGFTVLLWVFGAPLGAALGFSQGYDAA
                     VALLALVLLHGFRLAGWQDVERSTEWGVLLLFGGGLTLSKALAASGAAAWLATQLGGP
                     LAALPAWVCIALMVLFALLLTEVTSNTASAALLIPLFLGLAPHVERAPLAVLVAVGTS
                     CAFMLPVATPPNAIVFGSGHVPQRMMILGGTGVTVLVYPALVLAALIAIA"
     gene            complement(2907..4160)
                     /locus_tag="P5537_04850"
     CDS             complement(2907..4160)
                     /locus_tag="P5537_04850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002945384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HRV77407.1"
                     /translation="MRQQNLLYAHSGGVTAVINASAAAVVVAARASGRVGKVFAARRG
                     IIGVLEEALVDTACLDEAALVRLARAPGGAFGSCRFDLPHDDGGKAMDRLFAVFDAHD
                     IGWLLYNGGNGSMDAVARIQAEAARRGHALVCVGVPKTVDNDIVGTDCCPGFGSAARY
                     LATSMLEAGLDTSSMVGSKGSVFVMEVMGRNTGWLAAATALAAQGDPDRAPHIVLVPE
                     AGFDEAAVLARVREVTERLGYCAVTVAEGIRRPDGSLLMEKSRDARGYVQLGGAGLAV
                     ARLINERLGYKFHWAIPDYLQRSAGHWLSATDRAQAEAVGRVAVEYALAGKGGTMPGI
                     RRLQDAPYRWDVVPVDAAAVANLERGLPDGFVRADGLHVTAAACDYMRPLIEGELAPP
                     VVGGLPDYGRWDWATVARRLPAWQG"
     gene            complement(4298..4951)
                     /gene="adk"
                     /locus_tag="P5537_04855"
     CDS             complement(4298..4951)
                     /gene="adk"
                     /locus_tag="P5537_04855"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011238689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004017 - adenylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HRV77408.1"
                     /translation="MRLILLGPPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGTP
                     LGLEAKKVMDAGGLVSDDIIIGLVKDRLQQDDCKAGYMFDGFPRTIPQADAMKDAGVP
                     IDFVLEIDVPDAEIVERMSGRRAHLASGRTYHVKYNPPKVEGKDDVTGEDLVQRDDDK
                     EETVKKRLDVYHSQTKPLVEYYSKWAASGDAKAPKVRKISGLGAVDAITASAFAALQ"
     gene            complement(5039..5812)
                     /gene="kdsB"
                     /locus_tag="P5537_04860"
     CDS             complement(5039..5812)
                     /gene="kdsB"
                     /locus_tag="P5537_04860"
                     /EC_number="2.7.7.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008690 - 3-deoxy-manno-octulosonate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0009244 - lipopolysaccharide core region
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
                     /protein_id="HRV77409.1"
                     /translation="MAASFRIVVPARYASTRLPAKPLADIGGKPMIVRVLERIEDAGA
                     SETWVATDHEGVRDAVQAAGGAVVMTRPDHPSGTDRLAEVALARGWADEDIVVNVQGD
                     EPLIDPAIVAAVAQALAADGEAAIATAAHAIHDPAEVFNPNVVKVVCDAAGRALYFSR
                     APIPWARDAWGGGERGLPAGLPVLRHVGLYAYRVGFLRRYAALAPSPLEHWEALEQLR
                     ALWHGYRIRVLELDQAPAAGVDTQEDLERVRAIFAAGGV"
     gene            complement(5821..6012)
                     /locus_tag="P5537_04865"
     CDS             complement(5821..6012)
                     /locus_tag="P5537_04865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004312605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trm112 family protein"
                     /protein_id="HRV77410.1"
                     /translation="MDARLLEILVCPLCKGPLDHLKDKQELVCKADRLAYPIRDGIPV
                     MLDEEARAMSAEEVDALRK"
     gene            complement(5993..7000)
                     /gene="lpxK"
                     /locus_tag="P5537_04870"
     CDS             complement(5993..7000)
                     /gene="lpxK"
                     /locus_tag="P5537_04870"
                     /EC_number="2.7.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004312607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009029 - tetraacyldisaccharide 4'-kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetraacyldisaccharide 4'-kinase"
                     /protein_id="HRV77411.1"
                     /translation="MAASAPAFWQRRGALAQALRPLSLLFGVLARLRRARTRPQRLPV
                     AVIVVGNIAVGGSGKTPVVDWLAGVLRAAGHRPGIVSRGHGGTASAQGGLALVPADGD
                     PGRYGDEPVLLARLTGCPLVVGHDRPAAARELLRLHPECDVLIADDGLQHYRLGRDLE
                     VAVVDAATLGNRLLLPAGPLREPLARLAEVDLVLAHGALDPELRTAIGDVPVFGMRLA
                     GDAVVALDDPARRLPLAALRGRRVHAVAGIGRPQRFFEQLAAAGLEVVAHAFPDHHRF
                     VAADLAFGDASPILMTAKDAVKCRAFAPADCWEYPVRAQIGSGAAERILEKLEDGRTS
                     A"
     gene            complement(7032..7457)
                     /locus_tag="P5537_04875"
     CDS             complement(7032..7457)
                     /locus_tag="P5537_04875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004385428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biopolymer transporter ExbD"
                     /protein_id="HRV77412.1"
                     /translation="MNFRRGSRNGEPEINLIPLIDVVLVIIIFLMLTTTFSKVSGLEI
                     KLPTAEAEGSEAETREIVVAVTAAGEVLVNRQAVGERGVEAIAAALGKSAPADGDTPP
                     VVVINADARTPHQSVVDVMQAAQRAGLPHITFATQSSAQ"
     gene            complement(7469..8077)
                     /locus_tag="P5537_04880"
     CDS             complement(7469..8077)
                     /locus_tag="P5537_04880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HRV77413.1"
                     /translation="MFAIIQAVGWPIWPLILASVIALALIIERSITLRRSRIVPPGLL
                     DKVLNDLRQIGPSAEMAERVAAHSPLGRVLAAGLRNVHSPREVMKESIEETGRAVVHE
                     LERFLTTLGTIAAISPLMGLLGTIIGMIDIFASQGVSGANPAQLAQGISIALYTTGLG
                     LIIAIPAMIFWRHFRALIDSFVIDMEQQAIKLVEVAHGERRA"
     gene            8440..9813
                     /gene="xseA"
                     /locus_tag="P5537_04885"
     CDS             8440..9813
                     /gene="xseA"
                     /locus_tag="P5537_04885"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HRV77414.1"
                     /translation="MPANPFLPANGAATPAAQVVSVSELNRMARELLESALPLMWVGG
                     EISNLVRAASGHVYFTLKDASAQVRCAMWRNRAQLLAFRPENGMRVEARALVTLYEAR
                     GDYQLSVEALRPAGIGSLFEAFNRLKAKLAAEGLFDEEGRRALPRYPRALGIVTSPQA
                     AALRDVLVTLRRRAPHLPVVLYPAPVQGADAPVRLLEAVRSAGRRAAEDGVDVLLLVR
                     GGGSIEDLWAFNDEALARALRACPLPVVCGVGHETDFTIADFAADLRAPTPTGAAELA
                     SAGWYAARAELAVLEPRLRRAVERRFGELAQRLDRAALRLVHPRERLRRERDTLARLG
                     ERLRHATARRLETADLRTTRAGLRLRAAAPRPQALAARVDMLGERLARAATRLLEARS
                     QRLEALAAHLQHLAPQAVLARGYAIARDERGRVLRNAASVPEGSAVSVQLADGRLDTR
                     VLGHGEA"
     gene            9962..10546
                     /locus_tag="P5537_04890"
     CDS             9962..10546
                     /locus_tag="P5537_04890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010931119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006801 - superoxide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-Mn family superoxide dismutase"
                     /protein_id="HRV77415.1"
                     /translation="MEHTLPALPYAKDALAPHISAETLEFHHGKHHQAYVTNLNNLIK
                     GTEYENLDLEAIVKKAPAGGVYNNSAQVWNHTFFWNCMSPNGGGEPAGALADAIKAKW
                     GSYDDFKKAFQASAVGNFGSGWTWLVKKADGSVDIVNMGAAGTPLTTGDKALLCIDVW
                     EHAYYIDYRNRRPDFVATFLDKLVNWDFAAKNFA"
     gene            10688..11245
                     /locus_tag="P5537_04895"
                     /pseudo
     CDS             10688..11245
                     /locus_tag="P5537_04895"
                     /inference="COORDINATES: protein motif:HMM:NF013045.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
     gene            11558..12634
                     /gene="tal"
                     /locus_tag="P5537_04900"
     CDS             11558..12634
                     /gene="tal"
                     /locus_tag="P5537_04900"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002944760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004801 - transaldolase activity [Evidence
                     IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HRV77416.1"
                     /translation="MNPLLQVRQHGQQIWLDNLSRTLLEEGHLARLVADDGVAGVTTN
                     PAIFHKAISGGRYYEDDLATLKQQPLSAEARYEALVIPDVQRACDLLAPLHRDSGGSA
                     GYVSLEVSPALAHDADGTVAAGLRLKAAVDRANLLIKVPATQAGLVAIERLIGEGVSV
                     NVTLMFSLAHCEAVGEAYLRGLARLRAAGGDLGGVMSVASLFLSRVDTLVDKLLEERG
                     GDQLALRGRSAVAMARLAYEAWQARFHGAGFEDLAAAGARPQFMLWASTGTKNPAYSD
                     LLYVEPLIGADTINTLPDATLDALRDHGRIASTLEEDVEQAAAHFTALAAAGIDLVAV
                     GERLQQEGLAQFEQAFAGLLELTA"
     gene            complement(12689..14584)
                     /locus_tag="P5537_04905"
     CDS             complement(12689..14584)
                     /locus_tag="P5537_04905"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HRV77417.1"
                     /translation="MSDFAGMEDLLQDFLVEAGDLLSDVDNKLVELEHSPEDPGLLND
                     IFRGFHTIKGGAGFLGAAELVTLCHLTESLFDRLRKHELEVTPERMDVILSATGAVRD
                     MFADLGRGSRPGPAAPDLLDALRVAVAGQPVAAAQAAVAAAEPADLRPAGVVLPRPGE
                     PDWDALYAAVTGVAAPAGQAAAIVRPAAAPTAPPAAAVADPVVAAAFGRRASDVPGAS
                     APVGRREGERQRDNSIRVDTARLDQVLNLSGEIGLTKNRLNALRSDILAGRTDTETLQ
                     ALDLAVSQLDLLVSDLQNAVMKTRMQPIGRLFHKYPRIARDLARNLGKEVELALVGED
                     TEIDKTMVEDLSDPIIHLIRNAVDHGIEDPAGRAAAGKPAKSVLRLEARQEGDHIVIT
                     VADDGRGMDPEKLRAKALAQGVITAEEASTLDERQSYDLIFLPGFSTAEKVSDVSGRG
                     VGMDVVRTNIQKLNGSIEIQSQLGKGTTLLIHLPLTLAILPVLLVRLGEQPFAVPLSM
                     VREILPIEPGGIQDVGGKATMVVRGEVLPIVPLSALLGWPREEVPQYGVVMQSGASVF
                     ILAIDSFAGREDAVIKSLEVFRPKGVAGVTTLANGQIVLILDMKELLESAGERRSVSR
                     STLFEAV"
     gene            complement(14661..15509)
                     /gene="cheZ"
                     /locus_tag="P5537_04910"
     CDS             complement(14661..15509)
                     /gene="cheZ"
                     /locus_tag="P5537_04910"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0050920 - regulation of chemotaxis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein phosphatase CheZ"
                     /protein_id="HRV77418.1"
                     /translation="MIKKPKADPMGDSDELQALFDSIAADPFAVAGGGVEPAATILPV
                     DDSGDNDELQALFDAVAEQAAEPAAVAATEESAAAASEGVVYNRLGQLARQVHDALRE
                     LGLDTTLHQAAEAVPDARQRLAYVARTTEQAASRVLNATDVAAPIQAELASGADVLCA
                     RWDELYAGRLSPEAFRELSADTRAFLGTVGEGARGTAAQLHEIMMAQDFQDLTGQVIK
                     RLVELTRTLETQLLQVLIEAAPAQALEPEQAAGLLNGPVIDPAGRSDVVQDQAQVDEL
                     LERLGF"
     gene            complement(15541..15939)
                     /gene="cheY"
                     /locus_tag="P5537_04915"
     CDS             complement(15541..15939)
                     /gene="cheY"
                     /locus_tag="P5537_04915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis response regulator CheY"
                     /protein_id="HRV77419.1"
                     /translation="MSDPKTRFLVVDDFSTMRRIVRNLLKELGFANVDEAEDGAVALQ
                     KLKSSPFDFVVTDWNMPNMDGLTLLQNIRRTPELKHLPVLMITAEAKKENIIAAAQAG
                     ASGYVVKPFTAATLAEKLDKIFEKMGRGRA"
     gene            complement(15970..16929)
                     /locus_tag="P5537_04920"
     CDS             complement(15970..16929)
                     /locus_tag="P5537_04920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HRV77420.1"
                     /translation="MEHNRHEESALFDAVDGRATLAGSNRMEILLFSLGTGEHFGINV
                     FKVREVSRTPFITRTPNMPPGVEGLISLRGNVIPVLSLGVILGLTPAGAPLGEAMMVT
                     EYSKRTLGFLVASVDRIVRVDWERVRAPENVSTGTQGFITAITELDDGRLVSILDVES
                     ILADTFGEAVVGDIAPIGHGHEVNVFFVDDSMVARRKITEVLDRLGVRHKHATNGMEA
                     WNRLDSLAAHAENTGRRLIDEIDLIMLDAEMPEMDGYVLTRRIKGDARFAGIPVVMHS
                     SLSSEANRAMGSRVGVDAYVAKFDAEVLADTIRPMLQRARRTS"
     gene            complement(16939..17907)
                     /locus_tag="P5537_04925"
     CDS             complement(16939..17907)
                     /locus_tag="P5537_04925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HRV77421.1"
                     /translation="MSELLKNIDARTRLAGTNKLEILLFTLGVDARSGCRETYGINVF
                     KVREVMRRPTITAAPDMPDAVQGMVSLRGALVPVVDLGRYVGVGDDAAREIMIVTEYN
                     GHTQGFLVEGVDTILRLDWSQMRVPPEMLTARLGGLVTAVTSLADGRLVMMLDVERVL
                     SETSRYDDAFLFRDIAPLPGAEAHMVYFADDSSVARKQIAQTLDAMGVRHVGAVNGRQ
                     AWEELTRVAARAEANGRKVTDFVSLVLTDVEMPEMDGFMLTRQIKADRRFAGIPVIMH
                     SSLSGSSNHQLGLSVGVDEYVSKFEPQRLSQVLARLLGMADAESGR"
     gene            complement(17924..18916)
                     /gene="motB"
                     /locus_tag="P5537_04930"
     CDS             complement(17924..18916)
                     /gene="motB"
                     /locus_tag="P5537_04930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein MotB"
                     /protein_id="HRV77422.1"
                     /translation="MSDDTQQPIVVKRIKKGGGGHHGGAWKIAYADFVTAMMAFFLLM
                     WLLGSTAQGDLEGIADYFQNPLKLAMQGGEGTGDSSSIIKGGGEDLSRKVGQVRRGDT
                     PSTRAINLDAAPARVKSEAEMAAQAIAERRERARLIDLKGKLEAVIEANPSLRQFKNQ
                     LLIDIVSEGLRIQLVDAQNRPMFTSASADLRPYTRELLREIAAALNDVDNRVSMSGHT
                     DSAQYAGGERGFSNWELSSNRANAARRELVAGGLEAGKMLRVVGLADTAHLNPDDPLD
                     PANRRISIVVLNRAAEEAMRSQQAPGATPSPGGAQVGRNPADMRGGPGIVPAPN"
     gene            complement(18993..19847)
                     /gene="motA"
                     /locus_tag="P5537_04935"
     CDS             complement(18993..19847)
                     /gene="motA"
                     /locus_tag="P5537_04935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor stator protein MotA"
                     /protein_id="HRV77423.1"
                     /translation="MFLIIGYVIILAASLGTYAVHGSLAALWVPMEYIAIIGLMIGGF
                     VAGNGPKAIKGTLGSLSLAVKGSKYNKALYVDLLALLFEILAKVRKEGLMSIENDIEN
                     PDSSPIFSKYPSVAADHHAVEFMTDYLRMMVGGNLNAFEIENLMDMEIETHHQEAHTA
                     PHVVSKVADAVPAFGIVVAVMGVVNVMGSVGQPPAVLGKMIGGALVGTFLGILVSYGF
                     VAPIASQLEQKVEESGKIYQVIKVVLLASMNGYAPQVAVEFGRKVLYSTDRPGFAELE
                     QEIKNRKG"
     gene            complement(20037..20621)
                     /gene="flhC"
                     /locus_tag="P5537_04940"
     CDS             complement(20037..20621)
                     /gene="flhC"
                     /locus_tag="P5537_04940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045893 - positive regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:1902208 - regulation of bacterial-type
                     flagellum assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar transcriptional regulator FlhC"
                     /protein_id="HRV77424.1"
                     /translation="MKNKSVIEEADDVRRAVEMVQLGARMQMLEVETRLSREKLLKIY
                     KEVRGASPPKGMLPFSTDWFMTWQPNVHSSLFMNLYRYFTGPAGVQGLDAILKAYHLY
                     LDHIETSVIEPALSLTRAWTLVRFFDADLLQMAACTRCGGEFVVHAHDPVHDYVCGLC
                     NMPSRAGSARRKTTARKAVAPTRKSASSRKAVAA"
     gene            complement(20632..20949)
                     /gene="flhD"
                     /locus_tag="P5537_04945"
     CDS             complement(20632..20949)
                     /gene="flhD"
                     /locus_tag="P5537_04945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045893 - positive regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:1902208 - regulation of bacterial-type
                     flagellum assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar transcriptional regulator FlhD"
                     /protein_id="HRV77425.1"
                     /translation="MDRPDFQEEIRELNLAYLMLAQQMLRSDRATALFRLGIDAAFAD
                     LIESMSAAKLVRMASSPTLLPCFRFDDAQLARLMAGEGRDAASAGLHAAILAAGKAAA
                     DAR"
     gene            complement(21106..23034)
                     /locus_tag="P5537_04950"
     CDS             complement(21106..23034)
                     /locus_tag="P5537_04950"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009975 - cyclase activity [Evidence IEA];
                     GO_process: GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HRV77426.1"
                     /translation="MPQPIDMKRYAQLKAAGDLPSPRGVALAIIRLTQSPDVSLAELG
                     RVIKGDPAFVGRLIKAANGLIAENRRAIVSVQEALMVLGLPAVRTLALGFSLLSTYRK
                     GTCQGFDYTRFWSSALLMAISMQALTQRVRVVAPDEAFSLGLLARVGELSLATLYPEA
                     FSRLLAELKRDPGLQQVVLEEQAFAMNHRELGAAMLADWGVPDALVQPVRFHEQPELA
                     GYGEESREAGIVQCLVLARAVAQLCLAPEAEHVRLMTPMLRLAGRLGLGRGEFVSLCE
                     RVGRDWAEWGKLLQIRTEDAPRFVEVGNAAAEAGGDSSKLLAEADGPQPIRALVLSGA
                     REDRALLRTELEAAGIAAFVATGADAALEAALDIQPQLLVADWSDEGERVVRGLREMR
                     IGRGAYVICVLAGEDEADLLAASAAGADDFLVRPLQRAVLTVRLRACLRTLVLQQELE
                     HEREELRHFAAELSISNRRLQEAALTDPLTGLPNRRQAIETMQAEWAAATRHSRAFAV
                     MIVDLDGFKTINDTHGHDVGDIALRQAAETLRAALRTQDLICRTGGDEFLVLCPDTDL
                     KAAMLVAERLRVAVQARPVETGGPQIFLTASLGVAMRVPDMDNVDALIKCADDGVYRA
                     KQRGRNCIAALQLDAGAG"
     gene            23187..23735
                     /locus_tag="P5537_04955"
     CDS             23187..23735
                     /locus_tag="P5537_04955"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HRV77427.1"
                     /translation="MKYCSNCGATVAFRIPPGDSLPRHVCEQCGTIHYQNPKLVVGAL
                     AEWGDRILLCRRAIEPRHGMWTLPAGFMENEETTAQAAARETLEEACARIEVGELYTL
                     IDVPHISQVHIIYRARLLDLDFRPGEESLEVALLREDEIPWDHIAFRSIAISLRHFFD
                     DRRSGHFQLHTASLAPPPPEWR"
     gene            23832..24416
                     /gene="rsxA"
                     /locus_tag="P5537_04960"
     CDS             23832..24416
                     /gene="rsxA"
                     /locus_tag="P5537_04960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018990134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HRV77428.1"
                     /translation="MTSYIFVVIGAVLVNNVVLVRILGLCPFMGVSKKLETAIGMGAA
                     TTFVLTVGAGTSYLIDHYLLQPFDLGYLRTLAFIVVIAAIVQLTELIIQKTSPLLHQV
                     LGIYLPLITTNCAVLGVPLLNVGMKHDLLESLLFGFGSSLGFTLALVLFAGIRERLDG
                     ADVPIAFRGTAIAMITAGFMSLAFMGFAGLDRFH"
     gene            24430..24981
                     /gene="rsxB"
                     /locus_tag="P5537_04965"
     CDS             24430..24981
                     /gene="rsxB"
                     /locus_tag="P5537_04965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxB"
                     /protein_id="HRV77429.1"
                     /translation="MFTAILVMAGIAIVLGLTLGYAAIRFKVEGDPLVEKIDAILPQT
                     QCGQCGFPGCKPYAEAIANGEADINQCPPGGEEGVRKLADLLGREFKPLSEEHGVEKP
                     KSVAVIDEQVCIGCTLCIQACPVDAIVGAAKQMHTVVEPLCTGCELCVAPCPVDCIAM
                     VPVAETVQTWKWKYPVVEIRKAA"
     gene            24978..26678
                     /gene="rsxC"
                     /locus_tag="P5537_04970"
     CDS             24978..26678
                     /gene="rsxC"
                     /locus_tag="P5537_04970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HRV77430.1"
                     /translation="MIGRLFKFHGGIKPDAHKNESAGVAIRKAPLPPRLVVPLRQSAR
                     AGASCIVAVGQKVLKGERIGEPEGFLGTAVHAPTSGTVTAIDSCPMAHPSGLDTPCVV
                     IEPDGEERWIEHATPFDHHTATREQALAWLRDCGIVGLGGATFPSHVKLGRGSGIETL
                     ILNGAECEPWITCDDRLMRERAADILAGANILRELIGARELIVGVEDNKPEAVAAMQA
                     AAAGTAARVVAVPALYPAGGEKQLIRVLTGVEIPYGKLGGDYGVQCFNVGTAHAVYRA
                     FIHGEPLISRIVTLTGNCETPGNWEVAIGTPVEDLLALARPRTDTDRYLMGGPMMGFA
                     MPRLDVPVVKGTNCIISASPRLFPPAPPEQPCIRCTECAKACPVELQPFELYWFSRSK
                     NFGKAQEYHLFDCIECGCCSYVCPAHIPLVDYFRFSKSEIWAREREKTAADQARERFE
                     FRNFRQEREKAEKAAKLAAKAAETRAKLAEAGPAEAPAATDAPAAEDPKKALIAAALA
                     RAKAQKAEIQPQNTDNLSPQTQAEIADIEARRKVLEAVAATPAPQAAEAAAAPDEPRP
                     "
     gene            26686..27702
                     /locus_tag="P5537_04975"
     CDS             26686..27702
                     /locus_tag="P5537_04975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HRV77431.1"
                     /translation="MIHSPYVRKPVSVQRTMGLVLLALVPGIVAHVVFVGAGVLVNLA
                     ISTLTAVAAEALMLRLRKRPVGIAVADLSAVVTAWLVTLCFPPIVPWWLTVCAVLVAI
                     VAVKHLYGGLGQNPFNPAMIAYCSMIVAFPALMSQWPPAGQLSFDTQLSLILGGPRDI
                     DGITGATALDALRTGLRSGVQTVDKVLEGSAFGALGGRGWEWVSIGYVAGGLFLLAMR
                     IITWHMPVAFIGVLAAIAGLFWLVDPGHFASPLFHLASGGAMLAAFFIVTDPVSGATT
                     PRGKLLFAGGIALIAWLIRNFGAYPEGIAFGVLLMNMCVPLLDMKTQPRVFGHRHDLE
                     GGGK"
     gene            27699..28367
                     /locus_tag="P5537_04980"
     CDS             27699..28367
                     /locus_tag="P5537_04980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HRV77432.1"
                     /translation="MSARYSATRTALRTGAIMLLFTLVFTALMAATWRITQPAIEASA
                     QDAQRRLIDEVLPPGSYDNDLLADVVRFGPAPQIGMDEGGRVWRARKGGEPVALVVEG
                     AATDGYAGRIALIVAVNTNGLLSGMRVTQHKETPGLGDYIDPKKDRRKDLPWIGQFAV
                     ATWKDVNTADWTVRKDGGTFGYRTGATISARAVVRAAGRTTAFVVERMEALFTAPAGG
                     VLGE"
     gene            28370..29089
                     /locus_tag="P5537_04985"
     CDS             28370..29089
                     /locus_tag="P5537_04985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit E"
                     /protein_id="HRV77433.1"
                     /translation="MSPQQFREIAWNGLWKQNTGLAQLLGLCPILAISNSMVNAVSLG
                     LATILVMALSNLAVSALRNFIPYEIRIPVFILIIAALVTVVDLSFNAFFHDLYLVLGI
                     FIPLIVTNCIVLARVEAYAAKNDPLTSTVDGIMMGIGLVWVLAVLGGMRELLGAGTLF
                     SGIEMIIPGASAWNVFGEHYPGFLIAILPPGAFFALGVLIAAFNAINVRLAARARRRP
                     PPAPTKTAEPEQDSAEPAAAS"
     gene            29107..29739
                     /gene="nth"
                     /locus_tag="P5537_04990"
     CDS             29107..29739
                     /gene="nth"
                     /locus_tag="P5537_04990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003906 - DNA-(apurinic or apyrimidinic
                     site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HRV77434.1"
                     /translation="MKREAIREFFRRLHDANPNPQTELEYASPYQLLVAVVLSAQATD
                     RSVNLATRRLFALAPTPDAMVSLGEEGIADCIKTIGLFRNKAKNTLALSRLLLERHGG
                     EVPAEREALEALPGVGRKTANVVLNTVFRQPAMAVDTHIFRLSNRTGLAPGKDVLEVE
                     KALLRRVPKDYLLDAHHWLILHGRYVCTARKPRCGECAVRDLCRFRDKTD"
     gene            29828..30262
                     /locus_tag="P5537_04995"
     CDS             29828..30262
                     /locus_tag="P5537_04995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1841 family protein"
                     /protein_id="HRV77435.1"
                     /translation="MFNPSRDQVRSFFIDTWRKARAKEVLTPMETIAADIIALHPEYH
                     TVVEDPEAVHRDFPPEAGQINPFLHLSLHLAIEEQLSIDQPPGIRAAFEAACQHRGNR
                     HDAMHDALECLGEMLFDAQRKGTPPDGAAYVGALRKRAGLAV"
     gene            30489..31616
                     /locus_tag="P5537_05000"
     CDS             30489..31616
                     /locus_tag="P5537_05000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HRV77436.1"
                     /translation="MPGLLTNVDPDGLLEYSVVYTDRSLNHMSQAFQGVMRELSATLK
                     KVYHAHAVAIVPGSGTFGMEAVARQFATGKKTLVIRNGWFSYRWTQIFEMGNIPAESV
                     VLKARQVRDEAQAPFTPAPIDEVVAAIREHRPDVVFAPHVETSAGMMLPDDYLRAVAD
                     ATHAVGGLFVLDCIASGTVWVDMDAVGVDVLVSAPQKGWSASPCCAMVMMSAAARERI
                     EGTTSTSFACDLKKWLQIMEAYEGGAHAYHATMPTDGLVTLRDVMRETEAYGFAKVKE
                     EQLELGRRVRALLEARGFASVAAAGFQAPGVVVSFTTDDGIKTGAKFAAAGLQVAAGV
                     PLACDERPDYKAFRIGLFGLDKLHHIERSVATLEKALDQVG"
     gene            complement(31724..33067)
                     /gene="hflX"
                     /locus_tag="P5537_05005"
     CDS             complement(31724..33067)
                     /gene="hflX"
                     /locus_tag="P5537_05005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HRV77437.1"
                     /translation="MQTDLADEPRKAIVASVQRPDVSDAEFEASLAELRELAKTLGYR
                     VVHTFTQKRAGFDTHGYLGVGKRQEVREFVAAQAGFEAAPTDTVPRTGTIEALLVDHE
                     ISPSQARNLELETGCEVMDRTMVILEIFHRNARSRAARAQVEIARLGYMAPRLREAAK
                     LAGPQGRQRSGVGGRGAGESHTELDRRKIRDRIAELQLEIVAMEAERKTQRARRQGRQ
                     SLASVALVGYTNAGKSTLMRALTGSEVLVANKLFATLDTTVRTLHPESVPRVLVSDTV
                     GFIKNLPHGLVASFKSTLDEALDAGLLLHVIDASDPGFERQLEVTDTVLAEISADEVP
                     RIRVFNKIDHVGDAAAQAECETALREKYPGCIVMSARRPDEVARLRQAIVAFFQQDLV
                     EAELLLPWSAQQLRKELYANCEVLEERAEDEGAVFRLRGEADTVERLRAQFALTR"
     gene            complement(33123..33521)
                     /gene="cueR"
                     /locus_tag="P5537_05010"
     CDS             complement(33123..33521)
                     /gene="cueR"
                     /locus_tag="P5537_05010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006878 - cellular copper ion homeostasis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(I)-responsive transcriptional regulator"
                     /protein_id="HRV77438.1"
                     /translation="MNIGKAAAASGVSAKMIRYYESIGLLPAARRTDSGYRFYTDEDV
                     HVLRFVRRARDLGFAVADIGELLALWHDQGRASADVKRIALGHVAALERKIAELQGMV
                     DTLRMLAAHCHGDARPDCPILTDLDAGGGR"
     gene            complement(33539..36076)
                     /locus_tag="P5537_05015"
     CDS             complement(33539..36076)
                     /locus_tag="P5537_05015"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HRV77439.1"
                     /translation="MFAMNAPVAQGAPARSLHIAGMNCASCVAHVEKALLKVEGVQAA
                     SVNLATETATVAAPATVPLSALIAAVEKAGYAVRREALELDIEGMSCAACVGRVEKVL
                     QRVPGVVTANVNLASRRAHVELAGGVPTAALVAAVQKAGFGAKPAAEVSEGAREADAA
                     AEEAALRRAVWIALALTLPVFVLEMGSHLIPGMHDWVMATIGHRESWLLQFVLTSAVM
                     FGPGLRFFRKGVPSLLRGAPDMNALVAVGTSAAWGYSVVALFAPGLLPAGTVNVYFEA
                     AAVIITLILIGRLLEARARGKTSDAIRRLMRIQPRTARVRRGGSIGAEVVEIPIAEVA
                     VGDVVEVRPGEKVAVDGEVVEGASFVDESMITGEPVPVEKRAGATVVGGTLNTRGAFA
                     FRATRVGADTVLAQIIRMVEAAQGAKLPIQARVDKVTMVFVPVVMGLAALAFLAWLLF
                     GAAWLPAEVPVLSFALVNAVAVLIVACPCAMGLATPTSIMVATGRAAQMGVLFRKGDA
                     LQLLRDAAVVAVDKTGTLTVGKPQLTDLVVEEGFARADVLARVAAVERASEHPIAEAI
                     VAAARAEGLEIAAAEGFAAEAGYGVRATVGGQRVEVGADRLMRRLGLELGIFADTAAR
                     LGDEGKSPLYAAIDGRLAAILAVADPLKPTSVAAVQALHALGLKVAMITGDNERTARA
                     IARQAGIDEVVAEVLPDGKVAALRRLAGRGEDGEAAGRRVAFVGDGINDAPALAEADV
                     GIAIGTGTDVAIESADVVLMSGDLMGVPRAIALSRATMRNIGQNLFWAFAYNSALIPL
                     AAGAFYPAFGLLLSPVFAAAAMSMSSVFVLGNALRLRRFGAEAPAAG"
     gene            36257..37843
                     /locus_tag="P5537_05020"
     CDS             36257..37843
                     /locus_tag="P5537_05020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA ligase (AMP-forming), exosortase A
                     system-associated"
                     /protein_id="HRV77440.1"
                     /translation="MNHTTLLHHLITASAARAPQAPALSFGGATQSYAELDAALSAFA
                     AGLLALGLERGERVGIYLDKRPETVTAFFGASAAGGVFVPVNPILKPEQVGYILQDCN
                     VRVLVTSPERFAALRDTLAQCHDLRHVVLTGKVETLPELPGASVLRWDELCAAPPAAG
                     HRIIDTDMAAILYTSGSTGRPKGVVLSHRNMVAGGKSVAQYLGNHPGDTLLAALPLSF
                     DAGFSQLSTAFHSGARVVLLNYLLPRDVLKAVEKDKVTGLTAVPPLWIQLSQLQWPET
                     VTEHLRYIANTGGRMPLETLTTLRGMLPKTRPFLMYGLTEAFRATFLPPEQADVRPDS
                     IGKAIPNAEIMVLREDGSECAPNEPGELVQRGALVAMGYWNDPEKTAERFKPLPARAP
                     GRQSGLVLPEIAVFSGDTVRRDEEGYLYFIGRRDEMIKTSGYRVSPTEVEEILYATRL
                     VGECAAFGVAHDTLGQSIVVIATAPAGGTLDTAALLAECRARMPAYMVPGRIEVREGP
                     LPRNPNGKIDRKTLASEVGD"
     gene            37905..39101
                     /locus_tag="P5537_05025"
     CDS             37905..39101
                     /locus_tag="P5537_05025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011238263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77441.1"
                     /translation="MSATSTVRYCTRASRTARHLAAIVVALAVPATQAEILRVGPGER
                     FNRIADAAKMAKDGDIVEILPGEYRGDVTTWRQKKLLIRGVGERPVLIADGKIAEGKA
                     IWVIRNGDFLIDNIEFRGARAADDNGAGIRFERGRLEVLNSVFIDNQNGILTANFDDA
                     ELVIRDSLFAQAPRQEQSLPHLLYVGRIARFEINGSRFHQGYRGHLLKSRARYNDIRY
                     NLLYDGPQGEASYEIDLPNGGLAFVVGNIIGQSAATQNPTVVAYGAERNAWPESALYL
                     AHNTLLSDRHTGTLFLRTWPDRLPENTAVVGINNLSVGLGSLTLANAGDYRGNLPLPP
                     GGLEDPDTLDFRPLGASLLRRLTSPAGSARGVSLQPEAEFALPIGTRPIKPPAQWLPG
                     ALQSGQ"
     gene            39200..>39488
                     /locus_tag="P5537_05030"
     CDS             39200..>39488
                     /locus_tag="P5537_05030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase"
                     /protein_id="HRV77442.1"
                     /translation="MRERFSGVLGTPDAAASLPGQLARLQFAAGALAYPADVATYQEG
                     GRVCLALGRPRFRDAALQQACTRQGAAAAWAQAFARFGDDAVHQAAGRFCVV"
BASE COUNT         5966 a        14549 c        13264 g         5709 t
ORIGIN      
        1 atgccgctgc cgccgcacgc ccccgagcag caacccttcg tgtcgatcca cctcgcctgc
       61 tacaacgagc cgcccgagat ggtgatcgcc accatcgaca gcctggcgga gatgaactat
      121 cagaacttcg aggtcctgat cctcgacaac aacacccgcg acgaggcgct gtggaagccg
      181 ctcgagcgcc gctgcgccga gctcggcccg cgcttccgct tcttccacct cgccaactgg
      241 cccggcttca aggccggcgc gctcaactac ggcctcaagg tcaccgaccc gcgcgccgag
      301 gtggtgggcg tggtcgacgc cgactacgtg gtggatcccg actggctggc ctgcctggtg
      361 ccgcacttcg accagcccga ggtcgccgtg gtgcaggcgc cgcaggccca ccgcgactgg
      421 gaggggcagc ccttcaagcg catgtgcaac tgggagttcg acggcttctt ccgcatcggc
      481 atgcaccacc gcaacgagcg caacgcgctg atccagcacg gcaccatgac catggtgcgc
      541 aggcgcgcgc tcgaggaggt cggcggctgg tccgagtggt gcatctgcga ggacaccgag
      601 ctcggcctgc ggctgatcga gaagggctac gacacgcgct acatcgacca catcctcggc
      661 cgcggcctca ccccctcggg cttcgccgcg atcaagagcc agcgcttccg ctgggccttc
      721 ggcgcgatgc agatcctcaa ggcccacctg ccgcacatga tcgggcgcag caccctcaac
      781 ctcgcgcagc gctaccactt cctcaccggc tggttcgcct ggctgggcga cgcgctgcag
      841 ctggtgttcg cgttcggcag cctgctgtgg accctgggca tcctgctgtt cccgaaggcc
      901 ttcggcctgc cggtggtgtc gctcgcgctg ccgatcttcg gcttcatgat cttcaaggcc
      961 gcgctcggcc ccatcctgta ccggcgcacc atggactgtc cgtggaagga catcctcggc
     1021 gcctcgatcc tgtcggtggg cctcgcacat gcgatcgcgc gcggcgtgtt cgccggcctg
     1081 gtgaagaaga agggcgtgtt cgtggtgacg cccaagggct ggcgaggcgg cggcgcgctc
     1141 gccttcttca acccgatccg cgaggagatc ggcatgctgg tcgcgctgct gatgggcgcc
     1201 gccaccctgg tcgcccagcg cggcgccaac aacctcgaga cccagctctg ggtcggcatc
     1261 ctgtgcctgc agtgcatccc ctacgtcgcc gcgatcctgt gccaggtggc ggcgtacatg
     1321 ccggagcgcg gagcgacggc gggggaaacg gcagcggcgt gaggtgtcag gcgtaaggtg
     1381 tcacgcgtga ggcgtgaggc gtaaggagcg gcgggcgctg cagcgctcgc agccttctcg
     1441 cagctctgta acggccgggc gcgggcgggc ctgctcctca cgcctcacgc cttgctcctc
     1501 acgcaatcgc aatcagcgcc gccagcacca gcgccgggta gaccagcacc gtcaccccgg
     1561 ttccgcccag gatcatcatc cgttgcggca catggccgct gccgaacacg atcgcgttgg
     1621 gcggggtggc gaccggcagc atgaaggcgc aggaggtgcc aaccgcgacc agcacggcga
     1681 gcggcgcacg ctcgacgtgc ggggcgaggc cgaggaagag cgggatcagc agcgccgcgc
     1741 tcgcggtgtt gctggtgacc tcggtgagca gcagcgcgaa cagcaccatc agcgcgatgc
     1801 acacccaggc cggcagcgcg gcaagcggac cgccgagctg ggtggcgagc caggccgccg
     1861 cgccactggc ggcgagcgcc ttgctcagcg tcagaccgcc gccgaagagc agcagcacgc
     1921 cccactcggt gctgcgctcc acgtcctgcc agcccgccag ccgaaagcca tgcaagagca
     1981 cgagcgcgag cagcgccacc gcggcgtcgt agccctggga aaagccgagg gcggcgccga
     2041 gcggcgcacc gaacacccat agcaggacgg tgaagccgaa gagcgcgagc atcctccgct
     2101 gcgccggcgt ccagccagca ggcggtggtg gaggcgtcac caccacgtcg agccgcggcc
     2161 gcagcaccag gcgcaggccg atctccatca gcggcatcat caccagcacc agcggcagac
     2221 cccagctcat ccattcggcg aagcccatgc ccaccgctgc ggcggcgatc gcgttgggcg
     2281 ggctgccgac cagggtgccg atgccgccga tgttggcgga gaaggccacc ccgagcagca
     2341 cgtacatcca ggtgcgccgg tgctcgtcga gcggcagcgg cgcgagcagg ccgagcgcca
     2401 gcggcagcat catcgccgcg gtcgcggtgt tgctgatcca catcgacagg aaggcggtca
     2461 gccagaacag ccagcgcacc gcgcgcccga agctggcgcc cgcgcgccgc agcacctggc
     2521 ccgccatcca gcggtccagg ccctggcgct gcagtccggc ggcgagcgcg aagccgccaa
     2581 ggaagaggaa gacgaccggg tcggcgaact gcagcaaggc ctcgggaaag gcgagcaccc
     2641 cgctcgcggc ggcgagcacg ggcaccagca gcgcggtcac gctcacgtgc aaggcctcgg
     2701 tgagccacag ccaggcgatc gtagcgagca gcgcaagccc cgcgccggcc cgatccggca
     2761 ggccgtcgag gccccactgc aggctcagga agagcacgcc ggcgacgacg agattgaggt
     2821 tccgcatcac ttgatccatc cctgcacggt agcgctaccg gctcgggcgc agccctgcac
     2881 gcgcaggagc ggcccggtca cccgcatcaa ccctgccacg ccggcagccg gcgcgccacc
     2941 gtggcccagt cccagcgccc atagtcgggc aggccgccca ccaccggcgg cgcgagctcg
     3001 ccctcgatca acgggcgcat gtagtcgcag gccgccgcgg tcacgtgcag cccgtcggcg
     3061 cgcacgaagc cgtccggcag gccgcgctcc aggttggcca ctgcggcggc atccaccggc
     3121 acgacgtccc agcggtaggg cgcatcctgc aggcggcgga tccccggcat ggtcccgccc
     3181 ttgccggcga gggcgtattc caccgccacc cgacccaccg cctcggcctg tgcgcggtcg
     3241 gtggccgaca gccagtgccc ggccgagcgc tgcagatagt cggggatcgc ccagtggaac
     3301 ttgtagccca ggcgttcgtt gatcaggcgt gccaccgcga ggccggcgcc gccgagctgg
     3361 acgtagccgc gcgcgtcgcg cgacttctcc atcagcaggc tgccgtccgg gcggcggatg
     3421 ccctccgcca ccgtcaccgc gcaatagccc agccgttcgg tgacctcgcg cacgcgggcg
     3481 aggacggccg cctcgtcgaa gcccgcctcc ggcaccagca cgatgtgcgg ggcgcggtcc
     3541 gggtcgccct gcgcggcgag cgcggtggcc gcggccagcc agccggtgtt gcgccccatg
     3601 acctccatga cgaagacgct acccttgctg cccaccatcg acgacgtatc cagccccgcc
     3661 tccagcatcg aggtggcgag gtagcgcgcc gccgagccga agccgggaca gcagtcggtg
     3721 ccgacgatat cgttgtccac cgtcttcggc acgcccacgc acaccagcgc atggccgcgc
     3781 cgcgcggcct cggcctggat gcgcgcgacc gcgtccatgg agccgttgcc gccgttgtag
     3841 agcagccagc cgatgtcgtg cgcgtcgaac accgcgaaca ggcgatccat cgccttgccg
     3901 ccgtcgtcgt gcggcaggtc gaaacggcag gaaccgaagg ccccgcccgg ggcgcgcgcc
     3961 aggcgcacga gcgccgcctc gtccaggcag gcggtgtcga ccagggcctc ctcgagcacg
     4021 ccgatgatac cgcgccgggc agcgaaaacc ttgccgaccc ggcccgaggc acgcgcggcc
     4081 acgacgaccg ccgcggcgct ggcgttgatg acggcggtga caccgccgga gtgggcatac
     4141 aggaggttct gctggcgcat cggccgggcc tcgttcgagc gttgccgcgc acccaggcgg
     4201 gcggacgttg cggcgagttc aaaagcacgc gcggccgctg ccccgtgggg gcgcggccgc
     4261 gccggatcgg gccgggcaag cccggccggg ttgctgctta ctgcagcgct gcgaaggcgc
     4321 tcgcggtgat cgcatccacc gcgccgagac cggagatctt gcgcaccttg ggcgccttgg
     4381 cgtcgcccga agccgcccac ttgctgtagt actcgaccag cggcttggtc tgcgagtgat
     4441 acacgtcgag gcgcttcttg acggtctctt ccttgtcgtc gtcgcgctgc accaggtctt
     4501 cgccggtcac gtcgtccttg ccctcgacct tgggcgggtt gtacttgacg tggtaggtgc
     4561 ggcccgaagc caggtgggcg cggcggccgc tcatgcgttc gacgatctcg gcgtccggca
     4621 cgtcgatctc gagcacgaag tcgatcggca cgccggcgtc cttcatcgcg tcggcctgcg
     4681 ggatggtgcg cgggaagccg tcgaacatgt agccggcctt gcagtcgtcc tgctgcaggc
     4741 ggtccttgac caggccgatg atgatgtcgt cggacacgag gccgccggca tccatgacct
     4801 tcttcgcctc caggcccagc ggggtgcccg ccttcaccgc ggcgcgcagc atgtcgccgg
     4861 tggagatttg cggaatgccg aacttctcct tgatgaagtt ggcttgcgta cccttgccgg
     4921 ctcccggcgg tcccaacaga atcagacgca tactccctcc cgtgaatggc cggccatcga
     4981 acatggccgt ttccttatcg aataagcagc cgaaacttaa ccgacgcgcg ccgggtggtc
     5041 aaacccctcc ggccgcgaag atcgcgcgca cccgctccag gtcttcctgc gtgtcgaccc
     5101 cggcggccgg cgcctggtcg agctcgagca cgcggatgcg gtagccgtgc cacagcgcgc
     5161 gcagctgctc gagcgcttcc cagtgctcca gcggcgaggg cgcgagcgcc gcgtaacggc
     5221 gcaggaagcc gacgcggtac gcgtacagcc cgacgtgccg cagcaccggc aggccggcag
     5281 gcaggccgcg ctcgccgcct ccccaggcat cgcgcgccca ggggatcggc gcgcgtgaga
     5341 agtacagcgc gcgcccggcg gcgtcgcaca ccaccttgac cacattgggg ttgaagacct
     5401 cggcagggtc gtggatggca tgcgcggcgg tcgcgatcgc agcctcgcca tcggcggcga
     5461 gcgcctgcgc taccgcggcg acgatcgccg ggtcgatgag cggctcgtcg ccctgcacgt
     5521 tcaccacgat gtcctcgtcg gcccagccgc gcgcgagggc gacctcggcg aggcggtcgg
     5581 tcccgctcgg atgatccggg cgggtcatca ccaccgcgcc gcccgcagcc tgcacggcgt
     5641 cgcgcacacc ctcgtggtcg gtggcgaccc aggtctcgct ggcgccagca tcctcgatgc
     5701 gctcgagcac gcgcacgatc atcggcttgc cgccgatgtc ggcgagcggc ttcgcgggca
     5761 agcgggtcga ggcgtagcgc gccgggacga cgatgcggaa gctcgcggcc atgtcgcgcc
     5821 tcacttgcgc agggcgtcga cttcctcggc gctcatcgcg cgcgcctcct cgtccagcat
     5881 caccgggatg ccgtcgcgga tcggataggc caagcggtcg gccttgcaca ccagctcctg
     5941 cttgtccttc aggtgatcga gcggcccctt gcacagcggg cagacgagga tttcaagcag
     6001 acgtgcgtcc atcttcgagt ttctccagga tgcgttcggc ggcgccggaa ccgatctgcg
     6061 cccgcaccgg gtattcccag cagtcggcag gcgcgaaagc gcggcatttt accgcatcct
     6121 tcgcggtcat caggatcggc gacgcatcgc cgaaggcaag atcggcggcg acgaagcgat
     6181 gatggtcggg aaaggcgtgg gcgaccacct ccagcccggc ggccgcgagc tgctcgaaga
     6241 agcgctgcgg ccgcccgatc ccggccactg catgcacccg ccgaccgcgc agcgccgcga
     6301 gcgggagacg gcgcgcgggg tcgtcgagcg cgaccaccgc gtcgccggcg agccgcatgc
     6361 cgaacaccgg cacatcgccg atcgccgtgc gcagctcggg gtcgagcgcg ccatgggcca
     6421 gcaccaggtc gacctcggcc aggcgcgcga gcggctcgcg cagcggcccg gcgggcagca
     6481 gcaggcggtt gcccagcgtg gccgcgtcca ccacggcgac ctcgaggtcg cggccaaggc
     6541 ggtagtgctg caggccgtcg tcggcgatga gcacgtcgca ctcgggatgg aggcgcagca
     6601 gctcgcgcgc ggcggccggg cggtcgtgcc ccaccaccag cggacagccg gtgaggcgcg
     6661 cgagcagcac cggctcgtcg ccgtagcggc cggggtcgcc gtccgcgggc acgagggcga
     6721 gcccgccctg cgcgctcgcc gtgccgccat gaccgcggct gacgatgccg ggacggtggc
     6781 cggctgcgcg caggaccccc gccagccagt ccacgaccgg tgtcttgccg ctgccgccga
     6841 cggcgatgtt gccgaccacg atcaccgcca ccggcagccg ctgcggccgc gtgcgcgcgc
     6901 gacggaggcg ggcgaggacg ccgaacagaa gggagagcgg acgcagggcc tgcgcgagtg
     6961 cgccgcggcg ctgccagaac gcgggggccg acgcggccat gctcagtccg ggcggcggag
     7021 gccgggcggc ctcactgcgc cgacgactgg gtggcgaagg tgatgtgcgg cagcccggcg
     7081 cgctgcgcgg cctgcatcac gtccaccacg ctctggtgcg gcgtgcgcgc gtcggcgttg
     7141 atcaccacca ccggcggcgt gtcgccgtcg gccggagccg acttgccgag cgcggcggcg
     7201 atcgcctcga cgccgcgctc gcccaccgcc tggcgattca ccagcacttc gccagcggcg
     7261 gtcaccgcca ccacgatctc gcgcgtctcg gcctcgctgc cctcggcctc ggcggtgggc
     7321 agcttgatct ccaggccgga gaccttggag aaggtggtgg tcagcatcag gaagatgatg
     7381 atcaccagca ccacgtcgat gagcgggatc aggttgatct cgggctcgcc gttgcggctg
     7441 ccgcggcgga agttcatcgc ccgctcccct acgcccggcg ctcgccgtgt gcgacctcga
     7501 cgagcttgat cgcctgctgc tccatgtcga tcacgaagct gtcgatcagc gcgcggaagt
     7561 ggcgccagaa gatcatcgcc gggatcgcga tgatgaggcc gagcccggtc gtatacagcg
     7621 cgatcgagat gccctgcgcg agctgggccg ggttggcgcc gctcacgccc tgcgaggcga
     7681 agatgtcgat catgccgatg atggtgccga gcaggcccat cagcgggctg atcgcggcaa
     7741 tcgtgccgag ggtggtgagg aaacgctcga gttcgtgcac caccgcgcgc ccggtctcct
     7801 cgatggactc cttcatcacc tcgcgcgggc tgtgcacgtt gcgcaggccg gcagcgagca
     7861 cgcgaccgag cggcgagtgc gcggcgacac gctcggccat ctcggccgag ggaccgatct
     7921 ggcgcagatc gttcaggacc ttgtcgagca gcccgggcgg cacgatgcgc gagcggcgca
     7981 gggtgatcga acgctcgatg atgagcgcca acgcgatgac cgacgccaga atcaggggcc
     8041 agatcggcca gccaacggcc tggatgatcg cgaacacgcg ggctcacctc ttcatgggaa
     8101 aggcgagact ctagcgccgc gcccccagcc cggcaagccg catgcatcac gccgcgcatg
     8161 ccggggcggc gcgcgcgccg cggcccgcag gcctcacacc cgtcggctgc gggacgggtc
     8221 gcggcaatcc acagaagctg tggataaatt tgtggacgat ttagggatcc tgcccgcaaa
     8281 gcccgcaacg gcaagctttc cctcactccg atgcaaaatt gtgcaagcat tcgaagtctt
     8341 atgaatcaat aacttgcgat atcacccctt atcgatcaag gacttgcgag cacgcccttg
     8401 acaaggtcga aggcctgtgg attccgctac aatccggcca tgcccgcgaa ccccttcttg
     8461 cccgcgaacg gcgccgcgac gcccgccgcg caggtcgtca gcgtctccga actcaaccgc
     8521 atggcgcgtg agctgctcga atccgcgctg cccctgatgt gggtgggcgg cgagatctcc
     8581 aacctcgtcc gtgccgcctc cggccatgtc tacttcaccc tcaaggacgc ctcggcccag
     8641 gtgcgctgcg cgatgtggcg caaccgcgcg cagctgctcg ccttccgccc cgagaacggc
     8701 atgcgcgtcg aggcacgcgc gctcgtcacc ctgtacgagg cgcgcggcga ctaccagctc
     8761 agcgtcgagg cgctgcgccc ggccgggatc ggcagcctgt tcgaggcctt caaccggctc
     8821 aaggccaagc tcgccgccga gggcctcttc gacgaggagg ggcgccgcgc gctgccgcgc
     8881 tacccgcgcg cgctcggcat cgtgacctcg ccgcaggccg cggcgctgcg cgacgtgctg
     8941 gtcacgctgc ggcggcgcgc gccgcaccta ccggtggtgc tctaccccgc gccggtgcag
     9001 ggcgcagatg cccccgtgcg cctgctcgag gcggtccgca gcgccggtcg gcgcgccgcg
     9061 gaggacggcg tggatgtgct gctgctggtg cgcggcggcg gcagcatcga ggacctgtgg
     9121 gccttcaacg acgaggccct ggcgcgcgcc ctgcgcgcct gcccgctgcc ggtggtgtgc
     9181 ggcgtgggcc acgagaccga cttcaccatc gccgacttcg ccgccgacct gcgcgcgccc
     9241 acgccgaccg gcgccgccga gctcgccagc gccggctggt acgccgcgcg cgccgagctc
     9301 gctgtgctcg aaccgcgcct gcgccgcgcc gtcgagcgcc gcttcggcga gctcgcccaa
     9361 cgcctcgacc gcgccgcgtt gcgcctggtg catccgcgcg agcgcctgcg ccgcgagcgc
     9421 gacaccctcg cacgcctggg cgaacgcctg cgccacgcca ccgcgcgccg gctcgaaacc
     9481 gccgacctgc gcaccacccg cgccgggctc cgcctgcgcg ccgctgcgcc acgcccgcag
     9541 gcgctcgccg cgcgcgtcga catgctcggc gagcgcctcg cgcgtgcggc cacgcgcctg
     9601 ctcgaggccc gcagccagcg cctcgaggcc ctcgccgccc acctccagca cctcgcgccg
     9661 caggccgtgc tggcgcgcgg ctatgccatc gcccgcgacg agcgcggccg cgtcctgcgc
     9721 aacgccgcca gcgtccccga gggtagcgcg gtgagcgtgc agctcgccga cggtcgtctc
     9781 gacacccggg tgctcgggca cggggaggcc tgaacgcacg ggtcgcgcga tcgggttccg
     9841 caaatccccc gcatgggctt aacatgcggg acacaagctt gttcgaggtc taaatccaga
     9901 ctaaaatggt ccggctttga ccccaacccg aacacagaca gaccaacgac ggagatcacg
     9961 catggaacac accctgcccg ccctgcccta tgccaaggac gccctcgccc cgcacatctc
    10021 ggccgagacc ctggagttcc accacggcaa gcaccaccag gcctacgtca ccaacctgaa
    10081 caacctcatc aagggcaccg agtacgagaa cctcgacctc gaggccatcg tcaagaaggc
    10141 gcccgccggc ggcgtgtata acaactccgc tcaggtgtgg aaccacacct tcttctggaa
    10201 ctgcatgtcg cccaacggcg gcggcgagcc cgccggcgcg ctcgccgacg cgatcaaggc
    10261 caagtggggc tcctacgacg acttcaagaa ggccttccag gcctccgcgg tcggcaactt
    10321 cggctctggc tggacctggc tggtcaagaa ggccgatggc tcggtcgaca tcgtcaacat
    10381 gggcgccgcc ggcaccccgc tgacgaccgg cgacaaggcc ctgctctgta tcgacgtgtg
    10441 ggagcacgcc tactacatcg actaccgcaa ccgtcgcccc gacttcgtcg ccaccttcct
    10501 cgacaagctg gtgaactggg acttcgcggc gaagaacttc gcctgatccc cgcagccggc
    10561 cggcggccgg ccttgttcga tgcgaaagcg acccgcgtgg tcgctttcgc gctttatggc
    10621 gccgccctgc cgaagtccgc gcgccgttca attcgggatg ggccaggcgc caccgaccgg
    10681 acgcgacatg ctcgaaatcc tctaccgcga cgactggttg gtcgcgatcc acaagccctc
    10741 gggcctgctc gtgcaccgca gcccgatcgc cgcgcacgag gaacgcttcg ccgtgcagct
    10801 actgcgcgac cagctcggcc gtcgcgtgta tcccgcccat cggctcgacc gcggcacctc
    10861 gggcgtgctg ctgttcgcgc tcgatcgaga cgtcgcgcgc acgctcgcgc agcgcttcga
    10921 gtcgcaggcg gtggacaagc gctatctggc ggtcgtgcgc ggccatccgc ccgagcacgg
    10981 cctcatcgac cacgccctcg tgcgccggct cgatgcggtg gagatccgcc gcggcaaggg
    11041 cgccggcgcg cgcgacatgc tccccgagga cgaggacgac agcgatgcgg cggaagtccc
    11101 ggagcccctc gcccagcccg cgcgcacccg cttccgccgc ctcgccacgg tcgagctgcc
    11161 gcatgcggtg gaccgctacc cgaccagccg ctacgcgctc gtcgagctct tccccgagac
    11221 cggccgccgc caccagctgc gccgtcacct caagcacatc gcccacccga tcatcggcga
    11281 cgccacctac ggcaagggcc gccacaaccg cctgttccag gcgctcttcg gcagccagcg
    11341 cctgctgctc gcgtgcacgc ggctggcgct ggcacatccg gtgacggagc gcccgctgga
    11401 gatcgaggcg ccgctggcgg aggattttgc cgccgtgctc gcggcactcg gctggcagac
    11461 ggcacagcgc aacactttcg aggcagaatc caggcttacc gccgcccgcg ggcccgcgcc
    11521 cgagcggcac ccttcccacg acactccagg caagacgatg aatccgctgc tccaggtacg
    11581 ccagcacggc cagcagatct ggctcgacaa cctctcccgc accctgctcg aggaaggcca
    11641 cctcgcccgc ttggtcgccg acgacggcgt cgccggcgtg accaccaacc cggcgatctt
    11701 ccacaaggcg atctccggcg ggcgctacta cgaggacgac ctcgccacgc tcaagcagca
    11761 gccgctgagc gcagaggcgc gctacgaggc cctggtgatc cccgacgtgc agcgcgcctg
    11821 cgacctgctc gcgccgctgc atcgcgacag cggcggcagc gccggctacg tcagcctgga
    11881 ggtgtcgccc gcgctcgccc acgacgccga cggcaccgtg gccgccggcc tgcgcctgaa
    11941 ggccgcggtc gaccgcgcca acctgctgat caaggtgccc gccacgcaag ccggcctggt
    12001 cgccatcgag cgcctgatcg gcgagggggt cagcgtcaac gtcaccctga tgttctcgct
    12061 cgcgcactgc gaggcggtgg gcgaggccta cctgcgcggg ctcgcgcgcc tgcgcgccgc
    12121 gggcggagac ctcggggggg tgatgtcggt ggcgagcctc ttcctgtcgc gggtcgacac
    12181 gctggtggac aagctgctgg aagagcgcgg cggcgaccag ctcgcgctgc gcggccgcag
    12241 cgcggtggcg atggcgcggc tggcctacga ggcctggcag gcgcgcttcc acggcgccgg
    12301 cttcgaggac ctggccgcgg cgggcgcgcg tcctcagttc atgctgtggg cgagcaccgg
    12361 caccaagaac ccggcctaca gcgacctgct ctacgtcgag ccgctgatcg gcgccgacac
    12421 catcaacacc ctgcccgacg ccaccctcga tgcgctgcgc gaccacggcc gcatcgcctc
    12481 cacgctggaa gaggacgtcg agcaggccgc cgcccacttc accgcgctcg ccgccgccgg
    12541 catcgacctc gtggccgtgg gcgagcgcct gcagcaggag ggcctggcgc agttcgagca
    12601 ggccttcgcc gggctgctcg agctcaccgc ctgagtcgcc acctcggttg ccaccccgtt
    12661 cgccagccca gcgcgaccgg ggcggcggct acaccgcctc gaacagcgtc gagcgcgaca
    12721 cgctgcgccg ctcgcccgcc gactcgagca gctccttcat gtcgaggatc agcacgatct
    12781 ggccgttggc gagcgtcgtg accccggcca cgcccttcgg ccggaagacc tcgagcgact
    12841 tgatcaccgc atcctcgcgt ccggcgaagc tgtcgatcgc gaggatgaac accgaggccc
    12901 ccgactgcat caccacgccg tactgcggca cctcctcgcg cggccatccg agcagcgcgg
    12961 acagcggcac gatcggcagc acctcgccgc gcaccaccat ggtggccttg ccgccgacgt
    13021 cctggatgcc gcccggctcg atcggcagga tctcgcgcac catcgacagc ggcaccgcga
    13081 agggctgctc gcccaggcgc accagcagca ccggcaggat cgccagggtg agcggcaggt
    13141 ggatcagcag cgtggtgccc ttgccgagct gcgactggat ctcgatgctg ccgttgagct
    13201 tctggatgtt ggtgcgcacc acgtccatgc cgacgccgcg accggatacg tcggacacct
    13261 tctcggcggt ggagaagccg gggaggaaga tgaggtcgta gctctggcgc tcatcgagcg
    13321 tgctcgcctc ctcggcggtg atcacgccct gggcgagcgc cttcgcgcgc agcttctcgg
    13381 gatccatgcc gcggccgtcg tcggccacgg tgatcacgat gtggtcgccc tcctggcgcg
    13441 cctccaggcg cagcaccgac ttcgccggct tgccggccgc cgcgcgcccg gcggggtcct
    13501 cgatgccatg gtccaccgcg ttgcggatga ggtggatgat agggtcggag agatcctcga
    13561 ccatggtctt gtcgatctcg gtgtcctcgc cgaccagcgc cagctcgacc tccttgccga
    13621 ggttgcgcgc gaggtcgcgg gcgatgcgcg ggtacttgtg gaagagccgg ccgatcggct
    13681 gcatgcgcgt cttcatgacc gcgttctgca ggtcggagac gagcaggtcg agctggctca
    13741 ccgccaggtc gagcgcctgc agggtctcgg tgtcggtgcg cccggcgagg atgtcgctgc
    13801 gcagcgcatt gaggcggttc ttggtgaggc cgatctcgcc cgagaggttg agcacctggt
    13861 cgagccgtgc ggtgtccacc cggatcgagt tgtcgcgctg gcgctcgccc tcgcgccgcc
    13921 cgaccggcgc gctggcgccg ggcacgtcgc tggcgcggcg gccgaaggcg gcggcgacca
    13981 ccggatcggc gaccgccgcg gcgggcggcg cagtcggcgc ggctgcgggt cggacgatgg
    14041 ccgcggcctg cccggcaggt gcggccactc cggtgaccgc ggcgtacaag gcatcccagt
    14101 cgggctctcc cggccgcggc aggacgaccc cggcgggccg caggtcggca ggctcggcgg
    14161 cagccaccgc ggcctgtgcc gctgcgaccg gctgcccggc gacggcgaca cgcagcgcgt
    14221 cgagcagatc gggcgccgcc ggccccgggc ggctgccgcg gccgaggtct gcgaacatgt
    14281 cgcgcactgc gccggtcgcg gacaggatca cgtccatgcg ctcgggcgtg acctcgagct
    14341 cgtgcttgcg caggcggtcg aagaggctct cggtgaggtg gcacagcgtg accagttcgg
    14401 ctgcgccgag gaagcccgcc ccccccttga tggtgtggaa gccacggaag atgtcgttga
    14461 gcaggccggg atcttccggg ctgtgctcga gctcgacgag cttgttatcg acgtcggaca
    14521 gcaggtcgcc ggcttcgacg aggaagtcct gcagcagatc ctccatcccg gcaaaatcac
    14581 tcacggtttg ctcctggtta cggcgactcc ccgacatcgg gggcccaccg gttcgcgcgg
    14641 ggtccggccc cgcgcttcga tcagaatccg aggcgctcga gcagctcgtc gacctgggcc
    14701 tggtcctgca ccacgtcgct acgcccggcc gggtcgatca ccggcccgtt gagcagcccg
    14761 gcagcttgct cgggctccag cgcctgtgcc ggggcggcct cgatcagcac ctgcagcagc
    14821 tgggtctcga gcgtgcgggt gagctcgacc aggcgcttga tgacctggcc ggtgaggtcc
    14881 tggaagtcct gcgccatcat gatctcgtgc agctgcgcgg cagtgccgcg cgcgccctcg
    14941 cccaccgtgc cgagaaaggc gcgcgtgtct gcagagagtt cgcggaaggc ctccgggctc
    15001 aggcggccgg cgtagagctc gtcccagcgc gcgcacagca catcggcgcc gctcgcgagt
    15061 tcggcctgga tcggcgccgc cacgtcggtg gcgttgagca cccggctggc cgcctgctcg
    15121 gtggtgcggg cgacgtaggc gaggcgctga cgcgcatccg gaacggcctc ggccgcctgg
    15181 tgcagggtgg tgtccaggcc gagctcgcgc agggcatcgt gcacctggcg ggcgagctga
    15241 ccgaggcggt tgtagaccac cccctcgctg gccgccgcgg cggactcctc ggtcgctgca
    15301 accgcagccg gctccgcggc ctgctcggcg accgcgtcga agagcgcctg cagctcgtcg
    15361 ttgtccccgg aatcgtcgac cggcaggatc gttgccgccg gctccacgcc gcctcccgcc
    15421 acagcgaagg ggtccgcggc gatgctgtcg aagagggcct gcaattcgtc cgaatcgccc
    15481 atcggatccg ccttgggctt cttgatcata tccatgctcc gtctgcgctg cggacgcggc
    15541 ttacgcccgg ccgcggccca tcttctcgaa gatcttgtcc agtttctcgg ccagcgtcgc
    15601 cgcggtgaag ggcttgacca cgtagccgct ggcgcccgcc tgggccgcgg cgatgatgtt
    15661 ttccttcttg gcctcggcgg tgatcatcag caccggcagg tgcttgagct cgggcgtgcg
    15721 gcggatgttc tgcagcagag tcaggccgtc catgttcggc atgttccagt cggtgacgac
    15781 gaagtcgaag ggactggact tgagcttttg cagcgccacc gcgccgtcct cggcctcgtc
    15841 cacgttggcg aagccgagct ccttcaacag gttgcgcacg atgcggcgca tggtcgagaa
    15901 atcgtcgacg acgaggaagc gggtcttggg gtcggacatc ggggttctcc gggttctttg
    15961 cctgttcggt caggaggtcc gacgcgcccg ttgcagcatc gggcggatgg tgtcggccag
    16021 tacttcggcg tcgaattttg ccacgtaggc gtccaccccg acccgggagc ccatcgcgcg
    16081 gttggcttcg gacgacagcg aggagtgcat caccaccggg atgccggcga agcgcgcgtc
    16141 gcccttgatg cgccgcgtca agacatagcc gtccatctcg ggcatctcgg cgtcgagcat
    16201 gatgagatcg atctcgtcga tcagccggcg cccggtgttc tcggcgtgcg cggccaggct
    16261 gtcgagccgg ttccacgcct ccatgccgtt ggtcgcatgc ttgtggcgta cgcccaggcg
    16321 gtcgagcacc tcggtgatct tgcgccgcgc caccatggag tcgtcgacga agaacacgtt
    16381 cacctcgtgg ccgtggccga tcggcgcgat gtcgcccacc accgcctcgc cgaaggtgtc
    16441 ggcgaggatg gactcgacgt cgaggatcga caccaggcgg ccgtcgtcga gctcggtgat
    16501 cgcggtgatg aagccctgcg tgccggtgga cacattctcg ggggcgcgca cgcgctccca
    16561 gtcgacgcgc acgatgcggt cgaccgaggc gaccaggaag ccgagcgtgc gcttgctgta
    16621 ctcggtgacc atcatcgcct cgccgagcgg cgcccccgcg ggagtcaggc ccaggatgac
    16681 gccgagcgaa agcaccggga tgacgttgcc gcgcagcgag atcaggccct cgacgccggg
    16741 cggcatgttg ggcgtgcggg tgatgaaggg cgtgcgcgag acctcgcgca ccttgaagac
    16801 gttgatgccg aagtgctcgc cggtgccgag cgagaacagc aggatctcca tgcggttcga
    16861 gccggccagc gtggcgcggc cgtcgaccgc gtcgaacagg gcggattctt cgtggcggtt
    16921 gtgttccatg gcggttcctc agcgtccgct ctcggcatcg gccatgccga gcagccgcgc
    16981 cagcacctgg gacaggcgct gcggttcaaa cttggacacg tattcatcca ccccgaccga
    17041 gaggccgagc tggtggttcg agctgcccga cagcgacgag tgcatgatca ccgggatgcc
    17101 ggcgaagcgg cggtccgcct tgatctggcg ggtaagcatg aagccgtcca tctcgggcat
    17161 ctcgacgtcg gtcagcacca ggctgacgaa atcggtcacc ttgcggccgt tggcctcggc
    17221 gcgcgcggcc acgcgggtga gctcctccca ggcctggcgg ccattgaccg cgccgacatg
    17281 gcgcacgccc atggcatcca gggtctgcgc gatctgcttg cgcgccaccg aggagtcgtc
    17341 ggcgaaatac accatgtgcg cttccgcgcc cggcagcggc gcgatgtcgc ggaacaggaa
    17401 ggcgtcgtcg tagcgcgagg tctcggagag cacacgctcg acgtcgagca tcatcaccag
    17461 gcggccgtcg gcgagcgagg tcaccgcggt gacgaggcct cccaggcgtg cggtgagcat
    17521 ctccggcggc acccgcatct gcgaccagtc caggcgcagg atggtgtcca cgccctcgac
    17581 caggaagccc tgggtgtggc cgttgtactc ggtgacgatc atgatctcgc gcgcggcatc
    17641 gtcgccgacc ccgacgtagc ggccgagatc gaccacgggc acgagcgcgc cgcgcaggct
    17701 caccatgccc tgcacggcgt cgggcatgtc gggcgccgcg gtgatggtcg gccgacgcat
    17761 cacctcgcgc accttgaaga cgttgatgcc gtaggtctcg cggcagccgc tgcgcgcgtc
    17821 cacgccgagc gtaaacagca ggatctcgag cttgttggtg ccggcgagcc gggtgcgggc
    17881 gtcgatgttc ttcagcagtt cggacatggc tgcagccttg ggttcaattg ggcgccggga
    17941 caatccccgg gcctcccctc atatcggccg gattgcgccc gacttgagcc ccgcccggcg
    18001 acggcgtggc gccgggcgcc tgctggctgc gcatcgcctc ctccgccgcg cggttgagca
    18061 ccacgatgct gatgcgccgg ttggccggat cgagcggatc gtccgggttg aggtgagcgg
    18121 tgtcggcgag gccgaccacg cgcagcatct tgcccgcctc cagcccgccc gccaccagct
    18181 cgcggcgcgc ggcgttggcg cggttcgagg acagctccca gttcgagaac ccgcgctcgc
    18241 cgccggcgta ctgcgcggag tcggtgtgac cggacatgct gacgcggttg tcgacgtcgt
    18301 tgagcgcggc ggcgatctcg cgcagcagct cgcgcgtgta agggcgcagg tcggcgctcg
    18361 ccgaggtgaa catcggccgg ttctgcgcgt cgaccagctg tattcgcaac ccctcgctga
    18421 cgatgtcgat gaggagctgg ttcttgaact ggcgcagcga ggggttggcc tcgatgaccg
    18481 cctcgagctt gcccttgagg tcgatcaggc gggcacgctc gcggcgctcg gcgatcgcct
    18541 gcgcggccat ctcggcctcg ctcttgacgc gtgcgggcgc ggcgtcgagg ttgatcgcgc
    18601 gcgtgctcgg cgtgtcgcca cggcgcacct ggccgacctt gcgcgacaga tcctcgccgc
    18661 cacccttgat gatgctggag ctgtcgccgg tgccctcgcc gccctgcatg gcgagcttga
    18721 gcgggttctg gaagtagtcg gcgatgccct cgaggtcgcc ctgcgcggtc gagccgagca
    18781 gccacatcag caggaagaag gccatcatcg cggtcacgaa gtccgcgtag gcgatcttcc
    18841 acgcaccgcc gtggtggcca ccgccaccct tcttgatgcg cttgacgacg atcggttgct
    18901 gggtgtcgtc gctcatcgcg cggctccgca cgccggcgca gggcgcgaca cctggggacg
    18961 acgggaatca gggaggcggc ggctcatcgc gctcagccct tgcggttctt gatttcctgc
    19021 tcgagctcgg cgaagcccgg gcggtcggtc gagtacagca ccttgcggcc gaactccacc
    19081 gcgacctggg gcgcgtagcc gttcatgctc gccagcagca cgaccttgat cacctggtag
    19141 atcttgccgc tctcctcgac cttctgctcg agctggctgg cgatcggcgc gacgaagccg
    19201 tacgacacga ggatgccgag gaaggtgccg acgagcgcgc cgccgatcat cttgcccagc
    19261 accgccggcg gctggcccac cgagcccatc acgttcacca cgcccatcac cgccaccacg
    19321 atgccgaagg cgggcaccgc gtcggcgacc ttggagacca cgtggggagc ggtgtgcgcc
    19381 tcctggtggt gggtctcgat ctccatgtcc atcaggttct cgatctcgaa ggcgttgagg
    19441 ttgccgccca ccatcatgcg caggtagtcg gtcatgaact cgaccgcgtg gtggtcggcg
    19501 gcgacgctcg ggtacttgga gaagatcggg ctggagtcgg ggttctcgat gtcgttctcg
    19561 atcgacatca ggccctcctt gcgcaccttg gcgaggatct cgaacaacag cgcgagcagg
    19621 tccacgtaga gcgccttgtt gtacttcgag cccttcaccg ccagcgacag cgagccgagc
    19681 gtgcccttga tcgccttcgg accgttgccg gcgacgaagc caccgatcat caggccgatg
    19741 atcgcgatgt actccatggg cacccacagc gcggccaggc tgccgtgcac cgcgtaggtg
    19801 cccagcgagg cggcgaggat gatgacgtag ccgatgatca ggaacacggg gaaactccgg
    19861 agcgtttcgc tgcgccgcgc gcggaccggc acggctctcg ctggggataa cggctgcagg
    19921 ccgaggaact tgaacgcgcc cttcgacgcc gcggtgcgtg cggatgcgac atgggccgcc
    19981 tgtcgccagc gcggcccatg ggggattcat cgagcgggcc gggcggcccg ccgggatcag
    20041 gcggcgaccg ccttgcggct cgacgcgctc ttgcgcgtgg gtgcgaccgc cttgcgggcc
    20101 gtggtcttgc ggcgcgccga gccggcgcgc gagggcatgt tgcagaggcc gcacacgtag
    20161 tcgtgcaccg ggtcgtgggc atggacgacg aactcgccgc cgcagcgggt gcacgcggcc
    20221 atctgcagca ggtcggcatc gaagaagcgc accagcgtcc acgcgcgggt gaggctcagc
    20281 gccggctcga tcacgctggt ctcgatgtgg tcgaggtaga ggtggtaggc cttgaggatc
    20341 gcgtccagcc cctgcacgcc agcagggccg gtgaagtagc ggtacaggtt catgaacagc
    20401 gaggaatgca cgttcggctg ccaggtcatg aaccagtcgg tggagaacgg cagcatgccc
    20461 ttcgggggcg aggcgccgcg cacctccttg tagatcttga gcagcttctc gcggctcagc
    20521 ctggtctcga cctcgagcat ctgcatgcgc gcgccgagct gcaccatctc gacggcacgg
    20581 cgcacgtcat cggcttcttc gatcacactc ttgttcttca ttcgatactc ctcagcgcgc
    20641 atcggccgcc gccttgccgg cagcgaggat cgccgcatgc aggcccgcgc tggcggcatc
    20701 ccgcccctcg cccgccatca gccgcgcaag ctgggcgtcg tcgaagcgga agcagggcaa
    20761 cagcgtcgga ctggacgcca tcctcaccag cttggccgcc gacatcgact cgatcaggtc
    20821 cgcgaacgcc gcatcgatcc cgagccggaa cagcgcggtc gcgcggtcgc tgcgcagcat
    20881 ctgctgcgcc agcatcagat aggcgaggtt gagttcgcgg atttcttcct ggaagtcggg
    20941 gcgatccatg tttttccatc ccgcacgggg atcaacgcct gcaacttaaa gtagtttctc
    21001 aggagcggca agcggggcac cccggctccg tgctgcattt cacacagcaa gtgtcgccct
    21061 ggaacaacac atgcctgcag ggcggtcgcc gcttcctgga ggcattcagc cggcgccggc
    21121 gtcgagctgg agcgcggcga tgcagttgcg gccgcgctgc tttgcacggt agacgccgtc
    21181 gtccgcacac ttgatcagcg catccacgtt gtccatgtcg ggaacgcgca tcgccacccc
    21241 gaggctggcg gtgaggaaga tctgcgggcc tccggtctcc accgggcggg cctgcacggc
    21301 tacgcgcagg cgctctgcga ccagcatggc cgccttcagg tcggtgtcgg gacacagcac
    21361 caggaactcg tcgccgccgg tgcggcagat caggtcctgg gtgcgcagtg ccgcgcgcag
    21421 cgtctccgcg gcctggcgca gcgcaatgtc gccgacgtcg tgcccatgcg tgtcgttgat
    21481 ggtcttgaaa ccatcgaggt cgacgatcat caccgcgaag gcgcgactgt gccgcgtagc
    21541 cgcggcccac tcggcctgca tcgtctcgat cgcctggcgg cggttgggca ggccggtgag
    21601 cgggtcggtc agcgctgcct cctgcaggcg ccggttcgag atcgacagct cggcggcgaa
    21661 gtggcgcagt tcctcacgct cgtgctcgag ctcctgctgc agcaccaggg tgcgcaggca
    21721 ggcacgcagg cgcaccgtga gcaccgcacg ctgcagcggg cggacgagga agtcgtccgc
    21781 cccggcggcg gaggcggcca gcaggtccgc ctcgtcctcg ccggcgagca cgcagatcac
    21841 gtacgcgcca cggccgatgc gcatttcacg caggccgcgc accacgcgct cgccctcgtc
    21901 ggaccagtcc gcgacgagca gttgcggctg gatgtcgagc gcagcctcga gcgcggcatc
    21961 cgcaccggtg gcgacgaaag ccgcgatccc cgcggcttcg agctcggtgc gcagcagcgc
    22021 ccgatcctcg cgagcgccgg acaggaccag cgcccgtatc ggctgggggc cgtcggcctc
    22081 ggcaagcagc ttgctcgagt cgccgcccgc ctcggccgca gcattgccca cctcgacgaa
    22141 gcggggcgca tcttcggtgc ggatctgcag cagcttgccc cactccgccc agtcgcgccc
    22201 gacgcgctcg cacagcgaca cgaactcgcc gcgccccagg ccgaggcgcc cggccaggcg
    22261 cagcatcggc gtcatcagac gcacgtgctc ggcctcgggc gcgagacaca gctgtgccac
    22321 cgcgcgcgcc agcaccaggc actgcacgat gcccgcctcg cgcgattcct cgccgtagcc
    22381 ggccagctcg ggctgctcat ggaaacgcac cggctgcacc agcgcatccg gcacccccca
    22441 gtcggccagc atcgcggcac cgagctcgcg atggttcatc gcgaaggcct gctcctcgag
    22501 caccacctgc tgcaggccgg ggtcgcgctt gagctcggcg agcaggcgag agaaggcctc
    22561 gggatagagg gtggcgagcg agagctcgcc cacccgtgcg agcaggccga ggctgaaggc
    22621 ctcgtccgga gctaccacgc gcacgcgctg cgtgagcgcc tgcatcgaaa tcgccatcag
    22681 cagcgcggac gaccagaaac gcgtgtaatc gaagccctgg caggtgccct tgcggtaggt
    22741 cgacaacaac gaaaagccga gcgccaaggt gcgcacggca ggcaggccga gcaccatcag
    22801 cgcctcctgc accgacacga tcgcgcgccg gttctcggcg atcaggccat tggccgcctt
    22861 gatcaggcgt ccgacgaagg cagggtcgcc cttgatcacg cgaccgagct cggcgagcga
    22921 gacgtccggc gactgcgtga gccggatgat cgcgagcgcc acgccgcgcg gcgaaggcag
    22981 gtcccccgcg gccttgagct gcgcatatcg cttcatgtcg atcggttgcg gcatcccttc
    23041 ctcactcgtc gcgttcgctc tcgcacctgc cgaaacattt tggcacagag gcctcatgaa
    23101 cggcagttcg gcctcgttct ttagcccttg cggccggaag acgggtcaaa gcgcgctaga
    23161 atcgccgaaa actcctgtcc gcgaccatga aatactgctc gaactgcggc gccaccgtcg
    23221 ccttccgcat cccgcccggg gacagccttc cccgccatgt ctgcgagcag tgcggcacca
    23281 tccactatca gaaccccaag ctggtggtag gcgcgctggc cgagtgggga gaccgcatcc
    23341 tgctgtgccg gcgcgcgatc gagccgcgcc acggcatgtg gacgctgccg gccggcttca
    23401 tggagaacga ggagaccacc gcccaggcgg ccgcgcgcga gacgctggaa gaggcctgcg
    23461 cacgcatcga ggtcggcgag ctgtacacct tgatcgatgt gccgcacatc agccaggtgc
    23521 acatcatcta ccgcgcccgc ctgctcgacc tcgacttccg ccccggcgag gagtcgctcg
    23581 aggtggcgct gctgcgcgag gacgagatcc cctgggacca catcgcgttc cgctcgatcg
    23641 cgatcagcct gcgccacttc ttcgacgacc gccgcagcgg ccatttccag ctccacaccg
    23701 ccagcctcgc cccgccgcct cccgagtggc gctgaggccc cgaggccgga ccgatacatg
    23761 cgcgcgcatc agggttgatg cggggctccg gcgaggagga taatcccgta attcccttcc
    23821 gcgcgcggat catgaccagc tacatcttcg tcgtcatcgg cgccgtcctg gtgaacaacg
    23881 tcgtactcgt ccgcatcctc gggctttgcc cgttcatggg cgtgtcgaaa aagctcgaga
    23941 ccgccatcgg catgggcgcg gccacgacct tcgtgctcac cgtcggcgcc ggcaccagct
    24001 acctgatcga ccattacctg ctgcagccct tcgatctcgg ctacctgcgc acgctggcct
    24061 tcatcgtggt gatcgcggcg atcgtccagc tcaccgaact catcatccag aagaccagcc
    24121 cgctgctgca ccaggtgctg ggcatctacc tgccgctgat caccaccaac tgcgcggtgc
    24181 tcggcgtgcc cctgctcaac gtcggcatga agcacgacct gctcgagtcc ctgctgttcg
    24241 gcttcggctc ctcgctcggc ttcacgctgg cgctggtgct gttcgccggc atccgcgagc
    24301 gcctggacgg cgccgacgtg ccgatcgcct tccggggcac cgcgatcgcg atgatcaccg
    24361 ccggtttcat gagcctcgcg ttcatgggct tcgccggcct cgaccgcttc cactgaggcc
    24421 cgcgccccca tgttcaccgc gattctcgtg atggccggca tcgccatcgt gctcggtctc
    24481 accctgggct acgccgcgat ccgcttcaag gtcgagggcg atccgctggt cgagaagatc
    24541 gacgccatcc tgccgcagac ccagtgcggc cagtgcggct tccccggctg caagccctac
    24601 gccgaggcga tcgccaatgg cgaggccgac atcaaccagt gcccgcccgg cggcgaggaa
    24661 ggcgtgcgca agctcgccga cctgctcggg cgcgagttca agccgctctc cgaggagcac
    24721 ggcgtcgaga agcctaagtc ggtcgccgtc atcgacgagc aggtctgcat cggctgcacg
    24781 ctgtgcatcc aggcctgccc ggtggacgcg atcgtgggcg cggccaagca gatgcacacc
    24841 gtggtcgagc cgctgtgcac cggctgcgag ctttgcgtgg caccctgccc ggtcgactgc
    24901 atcgccatgg tgccggtggc cgagaccgtg cagacctgga aatggaaata ccccgtggtc
    24961 gaaatcagga aggcagcatg atcgggcgtc tgttcaagtt ccacggcggc atcaagcccg
    25021 acgcacacaa gaacgaatcc gccggcgtcg cgatccgcaa ggcgcccttg ccgccacggt
    25081 tggtcgtgcc cctgcgccag agcgcgcgcg caggcgcgag ctgcatcgtc gcggtcggcc
    25141 agaaggtgct caagggcgaa cgcatcggcg agcccgaggg cttcctcggc accgcggtgc
    25201 acgcgcccac ctcgggtacc gtcaccgcga tcgactcctg tccgatggcc cacccctccg
    25261 gcctggacac gccctgcgtc gtcatcgagc ccgatggcga ggagcgctgg atcgagcacg
    25321 ccacgccctt cgatcaccac accgccaccc gcgagcaggc cctggcctgg ctgcgcgact
    25381 gcggcatcgt cggcctgggc ggcgcgacct tccccagcca cgtcaagctc ggccgcggca
    25441 gcggcatcga gacactgatc ctcaacggcg ccgagtgcga gccctggatc acctgcgacg
    25501 atcgcctgat gcgcgaacgc gccgccgaca tcctcgcagg cgccaacatc ctgcgcgagc
    25561 tcatcggcgc acgcgagctc atcgtcggcg tcgaggacaa caagcccgag gcggtcgccg
    25621 cgatgcaggc cgcagcggcc ggcaccgccg cccgcgtcgt cgccgtgccg gcgctctacc
    25681 ccgccggcgg cgagaagcag ctcatccgcg tgctcaccgg ggtcgagatc ccctacggca
    25741 agctcggtgg cgactacggc gtgcagtgct tcaacgtcgg caccgcgcac gcggtgtacc
    25801 gcgccttcat ccacggcgag ccgctgatca gccgcatcgt caccctcacc ggcaactgcg
    25861 agaccccggg caactgggag gtggcgatcg gcaccccggt cgaggacctg ctcgcgctgg
    25921 cacgccccag gaccgacacc gaccgctacc tcatgggcgg cccgatgatg ggcttcgcga
    25981 tgccgcgcct ggacgtcccg gtggtcaagg gcaccaactg catcatctcg gcctcgccgc
    26041 gcctgttccc gccggcaccg cccgagcagc cctgcatccg ctgcaccgaa tgcgccaagg
    26101 cctgcccggt cgagttgcag cctttcgagc tgtactggtt cagccgctcg aagaacttcg
    26161 gcaaggcgca ggagtatcac ctcttcgact gcatcgagtg cggctgctgc agctacgtgt
    26221 gcccggccca catcccgctg gtggactact tccgcttttc caagagcgag atctgggcgc
    26281 gcgagcgcga gaagacggcg gccgaccagg cgcgcgagcg cttcgagttc cgcaacttcc
    26341 gccaggagcg cgagaaggcg gagaaggccg ccaagctcgc cgccaaggcg gccgagacgc
    26401 gcgccaagct cgccgaggcc ggcccggcag aagcgcccgc ggcgaccgat gcgcccgccg
    26461 cggaagaccc caagaaggcc ctgatcgctg ccgcgctcgc ccgcgccaag gcgcagaagg
    26521 ccgagatcca gccgcagaac accgacaacc tcagcccgca gacgcaggcc gagatcgccg
    26581 acatcgaggc ccgtcgcaag gtgctcgagg cggtcgcggc caccccggcg ccgcaagccg
    26641 ccgaagccgc agcggccccc gacgagcccc gcccctgagc cccgcatgat ccactctccc
    26701 tacgtccgca aaccggtcag cgtgcagcgc acgatgggcc tcgtgctgct cgcgctcgtg
    26761 cccggcatcg tcgcccacgt cgtcttcgtc ggcgccggcg tgctggtcaa cctggcgatc
    26821 tccacgctca ccgcggtggc cgccgaggcg ctgatgctgc gcctgcgcaa gcgcccggtg
    26881 ggcatcgccg tagccgatct ctccgccgtg gtcacggcct ggctggtcac gctgtgcttc
    26941 ccgccgatcg tgccgtggtg gctcaccgtg tgcgcggtgc tggtggcgat cgtcgcggtc
    27001 aagcacctct acggcggcct cggccagaac cccttcaacc cggcgatgat cgcctactgc
    27061 tcgatgatcg tcgccttccc ggcgctgatg tcgcaatggc cgccggccgg ccagctgtcc
    27121 ttcgacaccc agctctcgct catcctcggc gggccgcgcg acatcgacgg catcaccggc
    27181 gccaccgcgc tcgacgcgct gcgtaccggg ctgcgctcgg gcgtgcagac cgtcgacaag
    27241 gtgctcgagg gctccgcctt cggcgcgctc ggggggcgcg gctgggagtg ggtgtcgatc
    27301 ggctacgtcg cggggggcct cttcctgctc gcgatgcgca tcatcacctg gcacatgccg
    27361 gtcgccttca tcggcgtgct ggcggccatc gccggcctgt tctggctggt cgatccgggc
    27421 cacttcgcct cgccgctgtt ccatctcgcc agcggcggcg ccatgctcgc cgccttcttc
    27481 atcgtcaccg acccggtctc gggggcgacc acgccgcgcg gcaagctgct cttcgccggc
    27541 ggcatcgccc tgatcgcctg gctgatccgc aacttcggcg cctaccccga gggcatcgcc
    27601 ttcggtgtcc tgctgatgaa catgtgcgta cccctgctcg acatgaagac ccagccgcgg
    27661 gtcttcggtc accgccacga tctcgaggga ggcggcaagt gagcgcgcgc tactccgcaa
    27721 cccgcaccgc cctgcgcacc ggggcgatca tgctgctgtt caccctggtg ttcaccgcgc
    27781 tgatggcggc cacctggcgc atcacccagc ccgcgatcga ggcctcggcg caggacgccc
    27841 agcgccgcct gatcgacgag gtgctgccgc cgggcagcta cgacaacgac ctgctcgccg
    27901 acgtggtgcg cttcgggccc gcgccgcaga tcggcatgga cgagggcggc cgggtctggc
    27961 gtgcacgcaa gggcggcgag ccggtcgcgc tggtcgtcga gggtgcggcc accgacggct
    28021 acgcgggacg catcgcgttg atcgtcgcgg tcaacaccaa cggcctgctc tctggcatgc
    28081 gcgtcaccca gcacaaggag accccgggcc tgggcgacta catcgacccg aagaaggacc
    28141 gccgcaagga cctgccctgg atcggacagt tcgcggtcgc cacctggaag gacgtgaaca
    28201 ccgccgactg gaccgtgcgc aaggacggcg gcaccttcgg ctaccgcacc ggcgccacca
    28261 tcagcgcccg cgccgtggtg cgcgcggccg ggcgcaccac ggccttcgtg gtcgaacgca
    28321 tggaagcgct ctttaccgcc cccgccggcg gcgtgctggg agaatgagca tgagcccgca
    28381 acaattccgc gagatcgcct ggaacggcct gtggaagcag aacaccggcc tggcgcagtt
    28441 gctcggcctg tgtccgatcc tcgcgatcag caacagcatg gtcaacgcgg tcagcctcgg
    28501 cctggcgacc attctcgtga tggcgctgtc caacctggcg gtgtcggcgc tgcgcaactt
    28561 catcccctac gagatccgca tcccggtgtt catcctgatc atcgcggcgc tggtcacggt
    28621 ggtggacctc tccttcaatg ccttcttcca cgacctctac ctggtgctcg gcatcttcat
    28681 cccgctgatc gtcaccaact gcatcgtgct cgcgcgcgtc gaggcctacg cggccaagaa
    28741 cgacccgctc acctcgaccg tcgacggcat catgatgggc atcggcctgg tgtgggtgct
    28801 cgcggtactc ggcggcatgc gcgagctgct cggcgccggc acgctgttct cggggatcga
    28861 gatgatcatc ccgggcgcct cggcgtggaa tgtcttcggc gagcactacc ccggcttcct
    28921 gatcgccatc ctcccgcccg gcgccttctt cgcactcggc gtgctgatcg ccgcgttcaa
    28981 cgccatcaac gtgcgcctgg cggcgcgcgc gcgccggcgt ccgccgcccg cgccgacgaa
    29041 gacggccgag ccggagcagg actccgccga gccggccgcc gcgagctgac ggcccgcatg
    29101 gctgcgatga agcgcgaggc gatccgcgag ttcttccgcc gcctgcacga cgccaacccg
    29161 aacccgcaga ccgagctcga gtacgcctcg ccctaccagc tgctggtcgc ggtggtgctg
    29221 tcggcgcagg ccaccgaccg cagcgtcaac ctcgcaacgc gcaggctgtt cgcgctcgca
    29281 cccacgcccg acgccatggt ctcgctcggc gaggaaggca ttgccgactg catcaagacc
    29341 atcggcctgt tccgcaacaa ggcgaagaac acgctcgcgc tgtcgcgcct gctgctcgaa
    29401 cgccacggcg gcgaggtccc tgccgagcgc gaggcgctcg aggccctgcc cggcgtcggc
    29461 cgcaagaccg ccaacgtggt gctcaacacc gtcttccgcc aaccggcgat ggcggtcgac
    29521 actcacatct tccggctgtc caaccgcacc gggctcgcgc cgggcaagga cgtgctggag
    29581 gtcgagaagg cgctgctgcg gcgcgtgccc aaggactacc tgctcgacgc ccaccactgg
    29641 ctgatcctgc acggccgcta cgtgtgcacc gcgcgcaagc cgcgctgcgg cgagtgcgcc
    29701 gtgcgcgacc tgtgccggtt ccgcgacaag accgactgaa gccccgcgca ggtgcccgcc
    29761 ggcgcgacgc gctcgctgca cacccgccat cccgcgcccg agggcgcacg agaaccgagg
    29821 acccgacatg ttcaacccca gccgcgatca ggtgcgcagc ttcttcatcg acacctggcg
    29881 caaggcacgc gccaaggagg tgctgacgcc gatggagacc atcgccgccg acatcatcgc
    29941 cctccacccc gagtaccaca cggtggtcga ggacccggag gcggtgcacc gcgacttccc
    30001 gcccgaggcc gggcagatca accccttcct gcacctgtcg ctgcacctgg cgatcgagga
    30061 gcagctctcg atcgaccagc cgcccggcat ccgtgccgcc ttcgaggccg cctgccagca
    30121 ccgcggcaac cgccacgacg ccatgcacga cgcgctcgag tgcctcggcg agatgctctt
    30181 cgacgcccag cgcaagggca ccccgcccga cggcgcggcc tacgtcggcg cgctgcgcaa
    30241 gcgcgccggg ctggcggtct gatcgcagcc gcaacgcacc ccgtcccctc cctgccccac
    30301 ctccacgcct cgccctgcac acgggcgagg cgctagaatg aacgtcttcg gacgaatgga
    30361 tcggaccctg cgcgcccggc gattgccgcg ttcccggccc gcgcccggac atccgcgtcc
    30421 ctgaatcccc ccgactccac cgactcgctc acccttccgc caagaatccc cgcccccagg
    30481 aggtctccat gcccggtctg ctcaccaacg tcgatcccga tggcctgctc gaatactcgg
    30541 tggtctacac cgaccgctcg ctcaaccaca tgtcgcaagc cttccagggc gtcatgcgcg
    30601 aactctccgc gacgctgaag aaggtctacc acgcccacgc cgtggccatc gtccccggca
    30661 gcggcacctt cggcatggag gcggtcgcgc gccagttcgc caccggcaag aagaccctgg
    30721 tgatccgcaa cggctggttc agctatcgct ggacgcagat cttcgagatg gggaacatcc
    30781 ccgccgaatc cgtggtgctc aaggcccgcc aggtgcgcga cgaggcgcag gcgcccttca
    30841 ccccggcacc gatcgacgag gtcgtcgccg ccatccgcga gcaccgcccc gacgtggtgt
    30901 tcgccccaca cgtcgagacc tcggccggca tgatgctgcc cgacgactac ctgcgcgcag
    30961 tggccgacgc cacccacgcg gtcggcggcc tcttcgtgct cgactgcatc gcctcgggca
    31021 cggtgtgggt ggacatggac gcggtcggcg tcgacgtgct ggtgagcgca ccgcagaagg
    31081 gctggagcgc ctcgccgtgc tgcgcgatgg tgatgatgag cgccgccgcg cgcgagcgca
    31141 tcgagggcac caccagcacc agcttcgcct gcgacctcaa gaagtggctg cagatcatgg
    31201 aggcctacga gggcggtgcc cacgcctacc acgccaccat gcccacggac ggcctggtca
    31261 cgctgcgcga cgtgatgcgc gagaccgagg cctacggctt cgccaaggtc aaggaagagc
    31321 agctcgagct cggccgccgc gtgcgcgccc tgctcgaggc gcgcggcttc gccagcgtgg
    31381 cggccgccgg cttccaggcc ccgggcgtgg tggtgagctt caccaccgac gacggcatca
    31441 agaccggcgc caagttcgcc gccgccggcc tgcaggtcgc cgccggcgtg ccgctggcct
    31501 gcgacgagcg ccccgactac aaggccttcc gcatcggcct cttcggcctc gacaagctgc
    31561 accacatcga gcgcagcgtc gccacgctcg agaaggcgct cgaccaggtc ggctgatccg
    31621 gttcgatcca ccggacgcac gcgcgcctga agcggcacgg cgcgcgccaa cccgggcgca
    31681 tcgcctcacg cacaaacgcc acccttgcgg tggcgttcgt ttatcagcgt gtcagggcaa
    31741 actgcgcgcg caagcgctcg acggtgtcgg cctccccacg cagccggaag accgcccctt
    31801 catcctccgc ccgctcctcc agcacctcgc agttggcgta gagctccttg cgcagttgct
    31861 gcgccgacca cggcagcaac agctccgcct cgaccaggtc ctgctggaag aaggcgacga
    31921 tcgcctgccg aagcctggcc acctcgtccg gccggcgcgc gctcatgacg atgcagccgg
    31981 ggtatttttc gcgcagcgcg gtctcgcact cggcctgtgc cgcggcgtcg ccgacgtggt
    32041 cgatcttgtt gaagacgcgg atgcggggca cctcgtcggc actgatttca gccagcaccg
    32101 tgtcggtgac ctcgagctgg cgctcgaagc cgggatcgct ggcgtcgatg acgtgcagca
    32161 gcaggccggc gtccagggcc tcgtccaggg tggacttgaa cgaggccacc agaccgtgcg
    32221 gcaggttctt gatgaagccg acggtgtcgc tgaccagcac gcgcggcacg ctctcggggt
    32281 ggagcgtgcg cacggtggtg tcgagcgtgg cgaagagctt gttggcgacc agcacctcgc
    32341 tgccggtgag cgcgcgcatc agggtggact tgccggcatt ggtgtagccg accagcgcca
    32401 cgctggcgag gctctggcgc ccctggcggc gcgcacgctg ggtcttgcgt tcggcctcca
    32461 tcgcgacgat ctccagctgc agctcggcga tgcgatcgcg gatcttgcgg cgatcgagct
    32521 cggtgtgcga ctcgccggcg ccgcgaccgc ccacgccgct gcgctgccgc ccctgcggcc
    32581 cggcgagctt ggcggcctcg cgcaggcgcg gcgccatgta gcccaggcgg gcgatctcca
    32641 cctgcgccct ggccgcgcgc gagcgtgcgt tgcggtggaa gatctcgagg atgaccatgg
    32701 tccggtccat cacctcgcag ccggtctcca gctcgagatt gcgcgcctgc gagggcgaga
    32761 tctcgtggtc gaccagcagc gcctcgatcg tgccggtgcg cggcacggtg tcggtcggtg
    32821 cggcctcgaa gccggcctgg gcggccacga actctcgcac ctcctggcgc ttgccgaccc
    32881 ccagatagcc gtgggtgtcg aagccggcgc gcttctgggt gaaggtgtgc accacgcggt
    32941 agccgagcgt cttcgccagc tcgcgaagtt cggcgagcga ggcttcgaac tcggcgtcgc
    33001 tgacgtcggg gcgttgcacc gaggcgacga tggccttgcg gggttcgtcg gcgaggtctg
    33061 tttgcattca gggcacttct atcggtggga tggggtgcga tggtaacccg ccgcgccgcc
    33121 gttcagcgcc cgccgcccgc gtccaggtcg gtgaggatgg ggcagtccgg gcgcgcgtcg
    33181 ccatggcagt gcgccgcgag catgcgcagc gtatccacca tcccctgcag ctcggcgatc
    33241 ttgcgctcga gcgcggcgac gtgcccgagc gcgatgcgct tgacgtcggc gctcgcccgc
    33301 ccctggtcgt gccacagcgc gagcagctcg ccgatgtccg caaccgcgaa gccgaggtcg
    33361 cgcgcgcggc ggacgaagcg cagcacatgc acgtcctcgt cggtgtagaa gcggtagccc
    33421 gagtccgtgc gccgcgccgc cggcaacagg ccgatcgact cgtagtagcg gatcatcttc
    33481 gccgacacgc ccgaggcggc ggcggccttg ccgatgttca tcatgggctc gccctccctc
    33541 agcccgccgc cggcgcctcg gcgccgaagc gacgcaggcg cagcgcgttg ccgagcacga
    33601 acacgctcga catcgacatt gccgccgcgg cgaagaccgg cgacagcaac aggccgaagg
    33661 ccgggtagaa ggccccggca gcgagcggga tcagcgcgct gttgtaggcg aaggcccaga
    33721 acaggttctg gccgatgttg cgcatggtgg cgcgcgacag cgcgatcgcg cgcggcacgc
    33781 ccatcaggtc gcccgacatc agcaccacgt cggcgctctc gatcgccacg tcggtgccgg
    33841 tgccgatcgc gatgccgacg tcggcctcgg cgagcgcggg cgcgtcgttg atgccgtcgc
    33901 cgacgaaggc gacgcggcgg ccggccgcct ccccatcctc accgcgccca gccagcctgc
    33961 gcagcgccgc caccttgcca tccggcagca cctcggcgac cacctcgtcg atcccggcct
    34021 ggcgcgcgat cgcgcgcgcg gtgcgttcgt tgtcgccggt gatcatcgcc accttcaggc
    34081 ccagcgcatg cagcgcctgc accgccgcca ccgaggtcgg cttgagcggg tcggcgaccg
    34141 cgaggatggc ggcgaggcgg ccgtcgatcg ccgcgtagag cggcgacttg ccctcgtccc
    34201 caagccgcgc ggcggtgtcc gcaaatatgc ccagctccag ccccagccgg cgcatcaggc
    34261 ggtcggcgcc gacctcgacg cgctgcccgc ccaccgtcgc acgcacgccg tagccggcct
    34321 cggccgcgaa gccctcggcg gcggcgatct ccagcccctc ggcgcgcgcc gcggcgacga
    34381 tggcctcggc gatcggatgc tcggaggcgc gctcgaccgc cgccacccgc gccagcacgt
    34441 cggcgcgcgc gaagccctct tccaccacca gatcggtgag ctgcggcttg cccacggtga
    34501 gcgtgccggt cttgtccacc gccaccaccg ccgcgtcgcg cagaagctgc agcgcgtcgc
    34561 ccttgcggaa cagcacgccc atctgcgccg cgcgcccggt ggcgaccatg atcgaggtcg
    34621 gcgtcgccag ccccatcgcg cacgggcagg cgacgatcag caccgccacc gcgttgacca
    34681 gcgcgaagct gagcaccggc acctccgccg gcagccaggc cgcgccgaac agcagccagg
    34741 ccaggaaggc gagcgccgcc aggcccatca ccaccggcac gaagaccatg gtgaccttgt
    34801 ccaccctggc ctggatcggc agcttggcgc cctgcgccgc ctcgaccatg cggatgatct
    34861 gcgcgagcac ggtgtccgcc cccacccgcg tggcacggaa ggcgaaggca ccgcgggtgt
    34921 tgagcgtgcc gccgaccacg gtcgcgccgg cgcgcttctc caccggcacc ggctcgccgg
    34981 tgatcatcga ctcgtcgaca aacgaagccc cctccaccac ctcgccatcg accgccacct
    35041 tctcgcccgg gcgcacctcc accacgtcgc ccaccgccac ctcggcgatc ggaatctcca
    35101 ccacctcggc gcctatcgac ccgccccggc gcacgcgcgc agtgcgcggc tggatgcgca
    35161 tcaggcggcg gatggcgtcg ctggtcttgc cgcgcgcgcg cgcctcgagc aggcgcccga
    35221 tcaggatcag cgtgatgatc accgccgcgg cctcgaaata cacattgacc gtgcccgccg
    35281 gcagcagccc gggcgcgaac agcgccacca ccgaatagcc ccaggccgcc gaggtgccca
    35341 ccgccaccag cgcgttcatg tcgggcgcgc cgcgcaggag ggagggcacg cccttgcgga
    35401 agaagcgcag ccccggcccg aacatcaccg cgctggtgag cacgaactgc agcagccagc
    35461 tctcgcgatg gccgatcgtg gccatcaccc agtcgtgcat gcccgggatc aggtgcgaac
    35521 ccatctcgag cacgaacacc ggcagcgtca gcgccagcgc gatccacacc gcgcgccgca
    35581 gcgcggcctc ctcggccgcg gcgtcggcct cgcgcgcgcc ctcgctcacc tccgccgccg
    35641 gcttggcgcc gaagcccgcc ttctgcaccg ccgccaccag ggccgcggtc ggcacgccac
    35701 cggcgagttc gacgtgggcg cgccgcgagg ccaggttcac attggccgtc accaccccgg
    35761 gcacgcgctg cagcaccttc tcgacgcggc cgacgcaggc ggcgcagctc atgccctcga
    35821 tgtcgagctc tagcgcctcg cgccgcaccg cgtagccggc cttctcgacc gcggcgatca
    35881 gcgccgacag cggcaccgtg gccggcgcgg cgacggtggc ggtctcggtg gcgaggttga
    35941 cgctggccgc ctgcacgccc tcgaccttga gcaaggcctt ctcgacgtgg gcgacgcagg
    36001 aggcgcagtt catgcccgcg atgtgcaggc tgcgggcggg ggcgccctgg gcgacgggag
    36061 cgttcatggc gaacatccgt tcaaaaatgc gatgaatgcc tcgcactgta aaccttgcca
    36121 acattggaag gtcaacccgc aacgcgcatc tgcccgtgac gccttgccgt tgtggccccc
    36181 atgcaggggc gctaaccttg gcgcgatccg caaaccccgc gccccgcgcg cctctccagc
    36241 atcgccaccg gacgccatga accacaccac gctgctgcac cacctgatca ccgcctccgc
    36301 cgcacgcgca ccccaggccc ccgcgctgag cttcggcggc gccacgcaaa gctatgccga
    36361 gctcgatgcc gcgctgtccg cgttcgccgc cggactgctc gccctcgggc tggagcgcgg
    36421 cgaacgcgtc gggatctacc tcgacaagcg ccccgagaca gtcacggcct tcttcggcgc
    36481 cagcgcagcc ggcggcgtgt tcgtgccggt gaatcccatc ctcaagcccg agcaggtcgg
    36541 ctacatcctg caggactgca acgtacgcgt gctcgtgacc tcgcccgagc gtttcgccgc
    36601 cctgcgcgac accctggcgc agtgccatga cctgcgccac gtcgtgctca ccggcaaggt
    36661 cgagaccctg cccgaactgc ccggcgccag cgtgctgcgc tgggacgagc tgtgcgccgc
    36721 gccgcctgca gccggccacc gcatcatcga caccgacatg gccgccatcc tgtatacgtc
    36781 cggcagcacc gggcggccga agggggtggt gctgtcgcat cgcaacatgg tggccggcgg
    36841 caagagcgtc gcccagtacc tcggcaacca ccccggcgac accctgctcg ctgccctgcc
    36901 gctgtccttc gacgccggct tctcgcagct cagcaccgcc ttccactccg gcgcgcgcgt
    36961 ggtgctgctc aactacctgc tgccgcgcga cgtgctgaag gccgtggaaa aggataaggt
    37021 caccggcctc accgcggtgc cgccgctgtg gatccagctc tcgcagctgc agtggcccga
    37081 aaccgtcacc gagcacctgc gctacatcgc caacaccggc gggcgcatgc cgctggagac
    37141 gctcaccacg ctgcgcggca tgctgcccaa gacccggccc ttcctgatgt acggcctcac
    37201 cgaagccttc cgcgccacct tcctgccgcc cgagcaggcc gacgtgcgcc ccgactccat
    37261 cggcaaggcc atccccaacg ccgagatcat ggtgctgcgc gaggacggca gcgaatgcgc
    37321 gcccaacgaa ccgggcgagc tcgtgcagcg cggcgcgctc gtggccatgg gctactggaa
    37381 cgacccggag aagaccgccg agcgcttcaa gcccctgccc gccagggcgc cgggccgcca
    37441 gagcgggctg gtgctgcccg agatcgcggt gttctcgggc gacaccgtgc gtcgcgacga
    37501 ggagggctac ctctacttca tcggccgccg cgacgagatg atcaagacct cgggctaccg
    37561 cgtcagcccc accgaggtgg aagagatcct ctacgccacc cgcctggtcg gcgagtgcgc
    37621 ggcgtttggc gtggcgcacg acaccctcgg ccagagcatc gtcgtcatcg ccaccgcgcc
    37681 cgccggcggc acgctcgaca ccgccgcgct gctcgccgag tgccgcgcgc gcatgccggc
    37741 ctacatggtg cccggccgca tcgaggtgcg cgaagggccg ctgccgcgca accccaacgg
    37801 caagatcgac cgcaagacgc tggcgagcga agtgggagac tgaggtggag ctcgcggaca
    37861 agcccgtccc ctcaccaggc actcccggcc cggtgggagc tggcgtgtcc gcaacttcaa
    37921 cagttcgtta ctgcacgagg gccagccgga cagcacggca ccttgccgcg atcgtcgtcg
    37981 ccctcgccgt tccggccacc caagccgaga tcctgcgcgt cggccccggc gagcgcttca
    38041 accgcatcgc cgatgccgcc aagatggcaa aggatggcga catcgtcgag atcctccccg
    38101 gcgaataccg cggtgacgtc accacctggc gccagaagaa gctgctcatc cgcggcgtcg
    38161 gcgaacgccc ggtgctgatc gccgatggca agatcgccga gggcaaggcg atctgggtga
    38221 tccgcaacgg cgacttcctc atcgacaaca tcgagttccg cggcgcacgg gccgccgacg
    38281 acaacggtgc cggcatccgc ttcgagcgtg gccggctgga agtcctcaac agcgtcttca
    38341 tcgacaacca gaatggcatc cttaccgcca acttcgacga cgccgagctc gtgatccgcg
    38401 acagcctgtt cgcacaggcc ccccgacagg aacaatcgtt gccgcatctg ctctacgtcg
    38461 gccgcatcgc gcgcttcgag atcaacggca gccgcttcca ccagggctac cgcggccacc
    38521 tgctcaagtc gcgcgcgcgc tacaacgaca tccgctacaa cctgctctac gacggaccgc
    38581 agggcgaggc ctcgtacgag atcgacctac ccaacggcgg gcttgccttc gtggtcggca
    38641 acatcatcgg ccaatccgcc gctacgcaga acccgacggt ggtggcctac ggtgccgaaa
    38701 ggaacgcctg gcccgagagc gcgctctacc tcgcccacaa caccctgctc agcgaccgcc
    38761 acaccggcac gctgttcctg cgcacctggc ccgaccgcct gcccgagaac accgcagtcg
    38821 tcggcatcaa caacctcagt gtcggcctgg gcagcctgac gctggccaac gccggcgact
    38881 accggggcaa cctgcccctg cccccggggg ggctggaaga tccggacacc ctcgacttcc
    38941 gcccgctcgg cgcctccctg ctgcggcgcc tcacctcgcc tgcaggcagc gcacgcggcg
    39001 tgtccttgca gcccgaggcc gagttcgcgc tgccgatcgg cacccggccg atcaagccgc
    39061 ccgcgcaatg gctgcccggc gcgctgcaga gcggacagtg agccgagcgg tcacagttca
    39121 ctgacaatcc ctgccgcatg gggcatcatc gcggccgtcg aagcgaatac ggcccgtcat
    39181 gacggccgcg ggaggaaacg tgcgcgaaag attcagtggt gttctcggta cgccggatgc
    39241 ggcagccagc ctgcccggcc agctcgcgcg cctgcagttc gccgccggcg cgctggccta
    39301 tccggccgac gtcgccacct accaggaagg cggcagggtg tgcctcgcgc tcgggcggcc
    39361 gcgcttccgc gacgcagcgc tgcagcaggc ctgcacccgc cagggcgcgg cggctgcctg
    39421 ggcacaggcc ttcgcgcgtt tcggcgacga cgcggtgcac caggccgccg ggcgcttctg
    39481 cgtggtga
//
LOCUS       DAOTIN010000020        38899 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_1113_length_38899_cov_9.741479, whole genome shotgun sequence.
ACCESSION   DAOTIN010000020 DAOTIN010000000
VERSION     DAOTIN010000020.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 38899)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 38899)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38899
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1113_length_38899_cov_9.741479"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            30..641
                     /locus_tag="P5537_05035"
     CDS             30..641
                     /locus_tag="P5537_05035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77443.1"
                     /translation="MKKFIRDNPTIAFGLGLPLLLVAVFLAISGIPALLVAPPQYEVL
                     YATHYNFHNNAHNAIQIAVVGDRVQVSYVGNTQPYQTPRLWRFNPKTGAVREIALPLP
                     AGLAPNSGRPVEAEKTPSVTPIDVPDLAELKVDSSSLAPDGYTFRSSADSYGGNVFDG
                     LFFGSSRYRVQAELVKDGRSIRLPNTDGAHYGNTVRFVGWVLP"
     gene            638..1828
                     /locus_tag="P5537_05040"
     CDS             638..1828
                     /locus_tag="P5537_05040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77444.1"
                     /translation="MTWLLLLIVLVVLAGGWWGWPLAAALFGSRAIHDKTSALGKIAE
                     LMRAHDISPAEVAAVYRDPTLISTAAPKRSSGEIARTLFIYLGAIFILAGIGTYIGMF
                     WNRMGSVMRIVVTLGVGYALLVVLVSALHEKKFPRLVLPLTLATAFMLTSGWFVFIDE
                     VFPRGDDWRLAALAVFGTMAIHQGVLFRQYALSVLAFTALCFVYAFLSVGLDLLDVPA
                     GFSAILLGASLLLVASGLEKSPQRSLAEFAYLIALCWFNAGLFDRVAIAAAADWAALL
                     TGASVMSAAYGLHKDGRQLRLSGLGYLIGSALAYSGLFDLLRQTPVELLYFAVTAAML
                     YACVRLQSRALLLTTVLAMLGFIGYFTAEHFVDSLGWPISLVLMGVAFIGVGTLAMRI
                     KRQM"
     gene            2069..2338
                     /locus_tag="P5537_05045"
     CDS             2069..2338
                     /locus_tag="P5537_05045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix domain-containing protein"
                     /protein_id="HRV77445.1"
                     /translation="MTQAATKVLTAHVPLPLAEKVDQMAARLERSRGWIMKQALSAWI
                     AQEEERDRLTQEALADVDAGLVVDHLAVQAWADSLGTDQPLPLPR"
     gene            2338..2616
                     /locus_tag="P5537_05050"
     CDS             2338..2616
                     /locus_tag="P5537_05050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004637348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HRV77446.1"
                     /translation="MELKWTRKALADLTRLHEFLAPVNRQAAARAVQALAKAPTILLS
                     NPRIGEQLFQFAPREVRRILVAQYEVRYEIRDSVIYVLRLWHTREDRN"
     gene            2620..4074
                     /locus_tag="P5537_05055"
     CDS             2620..4074
                     /locus_tag="P5537_05055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3375 domain-containing protein"
                     /protein_id="HRV77447.1"
                     /translation="MPLDFATLDALRSHHPAWRLLRSDHAALVASFLHRVFVTPNVRG
                     MPAADLAEALEDELYALRLTRGEDAFPKAAIDYLDDWAAADKAWLRKYYKPGTDEAQF
                     DLTPATEKALAWLAQLSERQFVGTESRLLTLFALLKQMGEGSETDPARRIAELQRKRD
                     EIDAEMARVLAGDIPLLDDTAIKDRFQQFMQGARELLADFREVEHNFRQLDRRVRERI
                     ALWEGSKGALLEQIMGERDAIADSDQGRSFRAFWDFLLSSRRQEELSDLLDQVLALPA
                     VAELNPDARTRRVHYDWLEAGEHTQRTVAQLSQQLRRFLDDQAWLENRRIMDLLHGIE
                     SKALALRAAPPPGTAMEIALPGAAIELALERPLHTPPTRPAIAELRIEAGDEDVDPHA
                     LFEQVTVDKARLARHIRHALQDRAQVTLAALVAAQPLEQGLAELIAYLQLGSDAFTTT
                     LDEATPEPIEWEASATDGSTVTRRARLPRVIFMR"
     assembly_gap    4076..4175
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            4177..4848
                     /locus_tag="P5537_05060"
     CDS             4177..4848
                     /locus_tag="P5537_05060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4194 domain-containing protein"
                     /protein_id="HRV77448.1"
                     /translation="MDDEDLAPGPAEPAAPAPAPDLSVLLIGLLKGVLYREADERQWS
                     SLLQLQARVREYVAVLNLELVLDEAEGYAFLRGRPEPADDDPAPRLPRLVARRPLSYP
                     VSLLLALLRKKLAEFDAGGGDTRLVLGRDDIVELVRVFLPEGPNEARLIDQIETHINK
                     VVELGFLARLKPTSASTTAPASFEVRRILKAFVDAQWLADFDARLATYRAALADGKET
                     PSDDA"
     gene            5059..8481
                     /locus_tag="P5537_05065"
     CDS             5059..8481
                     /locus_tag="P5537_05065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HRV77449.1"
                     /translation="MNDPQSLGLDFVADDTLSGFRLQRLEVLNWGTFDRHVWTLQLDG
                     RNGLLTGDIGSGKSTLVDAITTLLVPAHRIAYNKAAGADTRERSLRSYVLGHYKSERN
                     EVTGAARPMGLREPGSYSVILGVFHNAGYDQTVSLAQVFWFKEPQGQPARFYLGAEHA
                     LSIAADFSGFGPDITQLRKRLRGAGAEVFDSFPPYAAWFRRRFGIDNEQALELFHQTV
                     SMKSVGNLTDFVRHHMLEPFEVGPRIQALIGHFDDLDRAHQAVLKAQRQVSLLAPLVE
                     DCHRHDALAADIGTLRRCREALQPHFAARKLALLDHRLALAAEEWARADAQVKRLDGL
                     REEQALRIDALKQAINANGGDRLERLAAEIRKLAQVRDARLAKSRRYAELAAVLGTPA
                     AADGEAFAAQRLHFAAGREDARSRDAELQNTLTEHAVSLRQGKLEHDALSAEIDSLRR
                     RRSNIDDRQIQIRAALCGALGIDVEDMPFAGELLQVREDERDWEGAAERLLRGFGLAL
                     LVPDAHYKAVAEWVDGNHLRGRLVYFHVRPPRTGELPALHPDSLVRKLAIKPDSPHYD
                     WLERELAHRFDVACCATQEQFRRETRAITRAGQIKDPSGRHEKDDRHAIADRSRYVLG
                     WSNTAKIEALEAQRRQLEARLGELGSQIGRIDTERRALAGRLDALTRLEEFTAFDELD
                     WHGVAGEIATLEDERRALEAASDLLKELGRQLAELQQIRVDTERELGAARERRAKVEQ
                     RQADAEDLRATTLALVDAAPIDPALVPQLEALCAEVLGEHQLTVESCDNREKEVRDLL
                     QTRIDAEDRRLARLAEKIIKAMSAFKQQFALETAEIDASLEAGFEYENLLTQLNRDDL
                     PRFLARFKELLNVNTINEIANFNAQLARERETIKERIAHINKSLGEIDYNPGRYIVLE
                     SQPSPDAEIRDFQQELRACTEGALSGAGEGDDEQYSEDRFLRVKGIIDRFRGREGLSD
                     QDRRWTAKVTDVRNWFLFAASERWREDDSEHEHYSDSGGKSGGQKEKLAYTILAASLA
                     YQFGLEWGAVRSRSFRFVVIDEAFGRGSDESAQYGLRLFEQLNLQLLIVTPLQKIHII
                     EPFVASVGFVHNEGGSASKLRNLSIEEYRAQKAEMRAAAQAAPRAGGAASAS"
     gene            8478..9686
                     /locus_tag="P5537_05070"
     CDS             8478..9686
                     /locus_tag="P5537_05070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2220 family protein"
                     /protein_id="HRV77450.1"
                     /translation="MSWSTVPDLKAQVMRLWERGELLREGLNAATSRFPLRLTLKTPG
                     PDDITRRFDAVRAWIAAISATPHVRLEWQETRHRVQGSQRLPASAWVDRLDDALAWIG
                     KRAEHARFRALHAETASRQPLLLPWLAKRPLRALELAAEWSRLLDVVAWLQAHPRPGV
                     YLRQVDLPGIHTKFIESQRGVLAELLELALPAAAIDPARTGAQQFAARYGFLDKPVLL
                     RLRILDPALHLLPGAPCPDLALDADSFARLRLDVARVFITENETNFLAFPRVDKAIVI
                     FGAGYGWEALARAEWLQRCPIHYWGDIDTNGFAILAQLRARFAHVESLLMDRATLLAH
                     EALWGREDSPRPADVSRLTAEERSLYEDLRDHRIRPSLRLEQEHIGFGWLEKWLKIVH
                     VMDDFQPSDG"
     gene            10052..11245
                     /locus_tag="P5537_05075"
     CDS             10052..11245
                     /locus_tag="P5537_05075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HRV77451.1"
                     /translation="MKIESIRLKNFKAFRNVHLKDIPSFLVVVGANGSGKSTLFDVFG
                     FLHDCLKGNVRQALDKRGRFGEVLSRGCDPKKDTLLIELQYRMEITGVERLVTYSLEI
                     GERQGMPVVCKELLRYKRGRYGSPYHFLSFAEGEGYAITNEEDFNKTDEELDRETQRV
                     APDTLAIKGLGQFERFKAANAFRSLIENWHVSDFHISAARGRKDASGEMEHLSETGEN
                     LPLVARYLHEQHAEIFSKILATMTKRVPGVTSVEPKLMDDGYLTLRFQDGSFKTPFLD
                     RYVSDGTIKMFAYLVLLHDPEPHPLLCVEEPENQLYPQLMPELAEEFRSYANRGGQVF
                     VSTHSPDFLNAIELDEVYWLVKQQGYSEIHRARDNAQIAAYVAEGDQLGYLWKQGFFD
                     GVDPR"
     gene            11242..11823
                     /locus_tag="P5537_05080"
     CDS             11242..11823
                     /locus_tag="P5537_05080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4276 family protein"
                     /protein_id="HRV77452.1"
                     /translation="MRELVFLLEEPSAKAMLESLRPRMLKQDTLFRCIPFEGKQDLEK
                     QLTRRIRAYQNERARFIVLRDQDSHPDCTAVKQGLLDLCDKSGKFARCLVRIACRELE
                     AFYLADLQAVERALEIDGLTRHQNSRKFRSPDGLGSPSRELKTLTRNRYEKVAGSRAI
                     GKHLQLDNARSASFRNLIAAIRRCEDELLREAV"
     gene            12156..13481
                     /locus_tag="P5537_05085"
     CDS             12156..13481
                     /locus_tag="P5537_05085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HRV77453.1"
                     /translation="MKSALFVDFDNVYSGLRKLDPAIADRFARQPLEWVNWVIGELEL
                     PDHAPAGARRRLLVRRCYLNPQAYQRFRPSFNLAGFEIIDCPALTSEGKTSTDIHMVL
                     DIIDLLQHEARYDEFIVFSADADFTPVLRKLRRWDRRTTVLAIGFPSAAYRASADLLI
                     DPDEFVRNALGFRDEDEAPATAADNADVDGPSAVASARAAQVMPDAPPIDPIDSAALD
                     RAVAEVVATMRAEVARATAPVPCSRLASLITTRHPALAADWNGKGSFRKFVDSLELAP
                     LRFDWSNSGGFVFDPARAGTGMQDGSATPDWGEDQDILPLAMQIHEVSGVPLLGPVEY
                     RALFSIIEDDAGRHPFDLKETGKRVRDRLREAGHGGSRLDVNWILRGLLMRGHAFGEG
                     QDRAATLATKTANNVRSLCLREQMILDRAAETAIARWFGTSPDARRMGQ"
     gene            13578..14180
                     /locus_tag="P5537_05090"
     CDS             13578..14180
                     /locus_tag="P5537_05090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77454.1"
                     /translation="MNTKTRSALRASLKQEDAALDERLPEAESPAAKTPPDAPVAAPE
                     RKPRARRAPPQGRTPAKTVAPGIARVATAAASAPAAPPARAASSIPAEPRPRSGTATQ
                     AAKPSKPKTEKRQRASFTLAASDLHRLDALRSAMKAAGRPARKSELVRAGLAALTALG
                     HADAIALLDALPPLKRTAGKGDEKGKAGKKKSAKRKAAAR"
     gene            14215..15675
                     /locus_tag="P5537_05095"
     CDS             14215..15675
                     /locus_tag="P5537_05095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/UbiB family protein"
                     /protein_id="HRV77455.1"
                     /translation="MDPDLATELFESLGLDALLPEPLAAWRPLLAEGMAFFLGRLPET
                     RLGAIVTEQLALAESASAAARATALLAHCPTLHKLGQVVARQPGLDAELRRHLQALES
                     LPANVEADTLHRQIAAELGADHGLHLADRALAEGSVAVVLPFSWRQGGRSHEGVLKAL
                     KPGIADRLGEELAILPALGDFLEGRGAELGLPAIDYHSHLAAAGRLLVQEIRLDREQA
                     NLRAAAALLVDDADVFVPTLLPWCTPALTAMERIDGPKLSDAALSTHESRRLGRALVG
                     GLLARPFWSCSENSPFHGDLHGGNLLLAPDGRVAVLDWSLVARLSKAEREALVEVALA
                     ALALDPSRITAGLAGLGLRDSRSTAIGATVERALDTLVRSGRPLGFDWLVGLLDALAL
                     QGASGFGEQLAVFRKSWLSLAGVLGDLGGGHDTDLPLLGLGLQRFTAEWPARLLAPAD
                     SRAFSTHVSTADLLRAAADAWPAGLRYWLRLLGHGH"
     gene            complement(15786..16445)
                     /gene="parA"
                     /locus_tag="P5537_05100"
     CDS             complement(15786..16445)
                     /gene="parA"
                     /locus_tag="P5537_05100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family partition ATPase"
                     /protein_id="HRV77456.1"
                     /translation="MSAPTLIALISQKGGSGKTTVAMQLAAGLALEGYRVALADLDPQ
                     ESASRWAESAPAEAPFPAQVVRLAGSADRMAKTLRPVANKVDVVVMDCPPSIEHAHTM
                     SALELCDIALVPVVPGPTDLWATRGIERLILERKRSRPGLRGALLPNRVTRTALSADV
                     LDVLRDFTLPVLDAALSQRSAYALSAVRGTSVFGLGRAAAPAQEEVARLVAAVVGLIE
                     D"
     gene            16620..17159
                     /locus_tag="P5537_05105"
     CDS             16620..17159
                     /locus_tag="P5537_05105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HRV77457.1"
                     /translation="MAREIERRFLVRDVRILDGRRGEHIIQGYLAKEIGSISTRVRIR
                     GERAYLTLKSPKQGFSRDEFEYPIPVGDARQMIAQHCAGRVVRKTRYLVDHAHHVFEV
                     DVFQGQHAGLVVAEVELPHEQTPLCLPHWVGDEITHDSRYGNFTLAEQAALLHAAATA
                     AIAAPAAVAKPILGLPVAH"
     assembly_gap    17190..17289
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(17319..19565)
                     /locus_tag="P5537_05110"
     CDS             complement(17319..19565)
                     /locus_tag="P5537_05110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004371001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HRV77458.1"
                     /translation="MRIVIVEDSPLLRDNLVRLLAAHPELCVVGSAAGEDDAFALIEA
                     QRPDTVLLDLSLSEGSGIGLLRRVRATPGLAPRVVVLSSRSADPWEAVCREAGADVFL
                     DKAEDTKVLLAQLASWMPPLPLDEPRRCRRLRQLQVLDTRPEPALDAIARLAARIAEV
                     PVGVISLVDSHRQRFKARVGTEMQTTSRTVSLCAHALVGEGLFEVEDATADPRFADNP
                     LVRGEPGVRFYAGMPLVMPGGEAVGTLCVLDTRPRRLGATAREALAVLARSVTDELEL
                     RQRVGELEEEVARRHEAEARIMQLATRDALTGLPNRAALMDRLHQGVRSAQRSGNLLG
                     VLFLDLDRFKWINDTLGHDLGDALLQEMALRLSRAVRESDTVARLGGDEFAIVLGDLW
                     QVADAEAVAAKVVDIVTRPLEVRGHALRVGGSVGVAVYPFQAHDEESLLRHADLAMYH
                     AKESGGNRHQLFSEHMNARAVERMTVESELRAAIAAGQLELHYQPQLCLEDRSLAGME
                     ALVRWRHPRLGLLAPGRFVPLAEDCGLIWELGLAVMELAVAQLAAWDRAGLQVPRIAV
                     NVSPAQLRPELVERIVEILERHGVDACRLEVELTESALTADGPAANGLLQALRRMGAS
                     IAIDDFGVGYSSLTLLRRLPISALKIDRSFVAELATNHQDAAIVEAILRMAHSVGLRT
                     VAEGVEHDGQDAVLGDLGCQEGQGYLFARPLDVAAATVWLAANAAGRRAAMTFDETGE
                     AMRLQAGA"
     gene            complement(19770..20411)
                     /locus_tag="P5537_05115"
     CDS             complement(19770..20411)
                     /locus_tag="P5537_05115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HRV77459.1"
                     /translation="MKLLIVDDHPVMRFGVRQLVTQRWPDAAIGEASCLAQALEQVRA
                     AEWELAVFDLSMPDTSGLEGLVRLHRAAPRTRLLVLSMHDEAAYAARALQLGAAGYLT
                     KEHATTELVAAIERVRGGQRYISSDLAARLADLLSGEAPARAPHETLSAQEYRVLLLI
                     AAGRSASEIAEAMHLSVKTVGTYRSRIIDKTGLANTAEMARYCSEHGLVDRGG"
     gene            complement(20408..21730)
                     /locus_tag="P5537_05120"
     CDS             complement(20408..21730)
                     /locus_tag="P5537_05120"
                     /inference="COORDINATES: protein motif:HMM:NF017077.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHASE3 domain-containing protein"
                     /protein_id="HRV77460.1"
                     /translation="MLFGLALFVALAWSSQASLHELEAVTDARSRSRSGLLLAAEVMS
                     ALKDVETGQRGYVLTGDEHYLDPVEIGMRRLDDTFEALRAMLADRPQARLDTLWTLID
                     HRVALAERNIADRRAYADEDSPWRRRLEEGRDTMDRIRVRFAAIEVMLRAEIEARDRS
                     VDALRTRASVFNFLLPLSGVALILAAWSLLQRERRRRIDAEVALIAANARLEDAVARR
                     TAELQQALGEIEAFAHGLDRSIEDERRRLAREVHDQLGQLLTALKMMVHRALQGAPGR
                     EQDWPQIEAVLGEGIATVRRISAALRPPLLDDLGLEAALGLACRQFAERTGVSCEATL
                     ADAGRLSANQANQLYRIAQEALTNVARHAQAGRVRVDGEAVEGEYRLAVEDDGVGMAP
                     QARSSLGLLSMRERAALAGGELRIGAGAAGGVRIEARVPLGAAGEDGG"
     gene            complement(21904..22434)
                     /locus_tag="P5537_05125"
     CDS             complement(21904..22434)
                     /locus_tag="P5537_05125"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77461.1"
                     /translation="MTIRSDIVYVARWWASPGEYKPWPEELVFFFEEAGTEIVPTLAE
                     AKKTLATLGSGAFVGGGIRHWCGIFACHVLHYAGVDVSWTLYGGRMKGNSGYQIQYVP
                     GDRNIRPGDVAVVPKAHHHFVVTAIDYDNNQLESVDGNTTGQYIRQRDKKIRYSWKDG
                     PDYASRNIYGYYRVLV"
     gene            complement(22636..23004)
                     /locus_tag="P5537_05130"
     CDS             complement(22636..23004)
                     /locus_tag="P5537_05130"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77462.1"
                     /translation="MKLLQPAARILALLALAGTAQAAQPPCTDADFEKFSLYDAAAMN
                     TRIPAQELRRVFSEQFGLEVGALNHLHARCNYALSARFTTQEEWNVFYRESLGKLKDF
                     CRKDGTPPYCEEAMRAEGPR"
     gene            complement(23081..23974)
                     /locus_tag="P5537_05135"
     CDS             complement(23081..23974)
                     /locus_tag="P5537_05135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004371014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bile acid:sodium symporter family protein"
                     /protein_id="HRV77463.1"
                     /translation="MNIDVLLPAALAFIMFSVGLALQGADFRRVFVRPRALLIGLVGQ
                     LVLVPLAALAVVLAFDLPPLLGMGLMVLAACPGGASSGFLTHLARANAALSLSLTVIS
                     SLAALLTFPLLVKAVLAAFGEGVFGADGGVLAELPVGRLIGSVLVVTTLPIVAGMLLR
                     LRAPAFTARAEPAIARVATLFFAAIVVATFVSHQHTILANLLSVGPATLVLNFAVMGL
                     GYGLVMLAGAERRDAVAVAMECGLQNAGLAIFVAIVLLRQPELAVGAVVYALTMNFGA
                     LGLVFVARRRETAGVLAAHGK"
     gene            complement(23984..24901)
                     /gene="menA"
                     /locus_tag="P5537_05140"
     CDS             complement(23984..24901)
                     /gene="menA"
                     /locus_tag="P5537_05140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046428 - 1,4-dihydroxy-2-naphthoate
                     octaprenyltransferase activity [Evidence IEA];
                     GO_process: GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     octaprenyltransferase"
                     /protein_id="HRV77464.1"
                     /translation="MTPLHPLPPRPGTLGVWWAAIRPRTLGMALAPVMLGTALAVADG
                     VELAWAVLLATAACALLIQIGTNLYNDAVDFERGTDRPERLGPLRVTLAGWASAAEVK
                     RGALLCLLLALLLGAWLCVVGGGLILAIGLASLVAGWAYSGGPRPISHSPLGELFVLL
                     FFGVFAVLGSHWLQSRAVGHLDLLAGLAVGAPAAAVLLVNNYRDLAGDLRAGRRTLAA
                     VLGAPRARRAFALLVLLPIPALVLMAASGVPGAILGLVGAPALAPLVWRFGRAEGGPA
                     LNALLVDTARAGTRTGLLAAAGIVFVSFL"
     gene            25109..26236
                     /locus_tag="P5537_05145"
     CDS             25109..26236
                     /locus_tag="P5537_05145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004379506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly(3-hydroxybutyrate) depolymerase"
                     /protein_id="HRV77465.1"
                     /translation="MKQFAPTLPPLARAAVLLISAVLAGGALAAPPGPLPALNIDIED
                     TSVSGISSGGFMSVQMQVAHSGIIRGAGVVAGGPYYCAQDSVMKATTECSCTGEPTLS
                     CKVADASAAVPELVAATRAFHAEGRIDDPAQIARQRVVTVVGGKDTLVPASITRQLHG
                     YYDAFGLPASALKPVTLDAAGHTMPTTAYGRACGVTDEPYIGKCGFEAAHAILDWIYG
                     PAVAPPRTTPTPAGRFAEFDQRGYIPETGIFSYLWGTGLDKTGWVYIPPACAAGERCR
                     LHVVFHGCKQGQSFLPLRRPPGGGLYNGTTFVRNTGYDRWADTNRLVVLFPQAVSIPW
                     KNPNGCWDWWGFTDADYATRDGIQIRSVRAMIERLASGRRD"
     gene            26367..27467
                     /locus_tag="P5537_05150"
     CDS             26367..27467
                     /locus_tag="P5537_05150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004379508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone Tir"
                     /protein_id="HRV77466.1"
                     /translation="MSYVGEPFRHDLFVSYSHGDDGSGGAYLKPWSAAFTHELERELR
                     ADRRFRTSLSVFRDQDHRPEQSLDPMAPLTAQLQEQIAGAALLVVLMSPDYLASKWCA
                     DERDWWLERQVALGLPHEERIAVVRIWPTDTPWPAALCDARGEPLVGFGFYPPAGVPP
                     RPLGWTDLPGAFGSEFRRALLDMVGRLYPKLETMRARAEELRRQREEAERLVRDGGQT
                     LYLHGRSDHAEAWEAAALKLVDKGFAVVPGEPDRVESDPARLQEVRERRVETLSGCDA
                     LLLLGTDDGRALDADLVVVGKHDRQSARARSHRLLPCGLLDTAGAAIATSVRRATARI
                     VQADWIDGTDEDWPVAVRDWLGGKGVQAGGAP"
     gene            27464..29848
                     /locus_tag="P5537_05155"
     CDS             27464..29848
                     /locus_tag="P5537_05155"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77467.1"
                     /translation="MKPDASAPATAEDTFDAVFAIRLPPRPYPGLRPFEQHEWPIFFG
                     RERMTDEIVERLLGLRLLVVHGDSGCGKSSLVRAGVLPRLEQESARGGVRWRTCTALP
                     RAAPLWNLAHALAALDTPGEGDADALEARTIAFRRALNFGREAPAALAELLGCGPRNQ
                     VCILVDQFEELFEHARRHGPEEAALLAACLVGLLDAPPPGLYAVLTMRSEFLGACSRY
                     EGFAAAVNRAQYLLPRMEHDDLMRAIREPAVLYDGEVTRELAERLIVDGGGGQDQLPL
                     IQHGLMLLHDEHARTSGQALAGPTPGAPAWRLGMEHYRAEDGLAGLLSAHADAVLARA
                     GQRCFGGEATRVVEDLFRALTDINAEGQAIRRPCTLERLVAVTGTNEPALRCVVDAFR
                     ADGVSFLKPYGHEALRAEELIDISHEALIRCWRRIAEPREGWLAREFRNGLVWRALLV
                     QADSFDRDPGNVLGATTTDERERWLRRRNAIWAERYGGGWERVQRLIAASVEARALRA
                     AEREAAETQRQEARRLRRRSRALAIGIGVLAFTSALGGLAWQQSRIAEDARRVAEGER
                     ELALTARDEVVRQLEALVEAREAEAAARAAAEAVAQEARQSASALAGVVDELERASSA
                     ANAPASGDGQAVQRSLSEAKSELRAQVSNLSKLSVQQAAPPLAAAPAPAPPGALAPRM
                     WIYIAEESQRPAAEALEAQLRSVRIGDAALELPGIVLVKAAPTRSMLRCFRTEECRQD
                     GDALVRALGGLLQSPKPSLEDFSALYGSSGSIRARHYELWFAPGAIVLPARKGP"
     gene            complement(29934..32171)
                     /locus_tag="P5537_05160"
     CDS             complement(29934..32171)
                     /locus_tag="P5537_05160"
                     /EC_number="1.1.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004450 - isocitrate dehydrogenase (NADP+)
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent isocitrate dehydrogenase"
                     /protein_id="HRV77468.1"
                     /translation="MSAGKSKIIYTLTDEAPLLATCAFLPIIRTFTGPAGVEVEKADI
                     SVSARVLAEFPEYLSEDQRVPDTLAELGRLTLEPDTNIIKLPNISASVAQLKACVKEL
                     QDKGYKIPDYPEDPKTDEEKALRARFGKCLGSAVNPVLREGNSDRRAPAAVKNFAKKN
                     PHSMGEWKQWSQTHVSHMHHGDFYHGEKSMTLDRARSVKMELITKSGKTVVLKPKTDL
                     LEGEIIDSMFMSKKALCEFYERELDDCREAGILFSLHVKATMMKVSHPIVFGHCVKIY
                     YKDAFEKHGKLFDELGINVNNGMVDLYDKIKTLPESKRDEIIRDLHACQEHRPALAMV
                     DSAKGITNFHSPNDIIVDASMPAMIRQGGKMWGADGKQYDSKCVMPESTFARIYQEMI
                     NFCKWHGNFDPRTMGTVPNVGLMAQKAEEYGSHDRTFEIVEAGVANITDLDTGEVLLS
                     QNVEEGDIWRMCQVKDAPIRDWVKLAVTRARNSGMPAIFWLDPYRPHENELIKKVKTY
                     LKDHDTSGLDIQIMSQVRAMRYTLERVARGLDTISVTGNILRDYLTDLFPIMELGTSA
                     KMLSIVPLMNGGGMYETGAGGSAPKHVQQLVQENHLRWDSLGEFLALAVSLEDLGIKT
                     GNGKAKLLAKTLDEATGRLLDENKSPSPKTGQLDNRGSQFYLAKFWAERLAGQTEDAE
                     LAAKFAPLAKALAENEQKIIAELSEVQGKAVDIGGYYKADAEKCKAVMRPSATLNAIL
                     KGARS"
     gene            32512..33378
                     /gene="nudC"
                     /locus_tag="P5537_05165"
     CDS             32512..33378
                     /gene="nudC"
                     /locus_tag="P5537_05165"
                     /EC_number="3.6.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000210 - NAD+ diphosphatase activity
                     [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) diphosphatase"
                     /protein_id="HRV77469.1"
                     /translation="MNLPSSPPACGDPRPASRSPARTLVFRGHQLLVDRAGAPSAGPS
                     AWRAGLAALRTLDFPMPSGGAWTVVEVERTIEAPDGHAFQHLKSLLDTLAEDRLALAA
                     RALELLEFDHAHRFCGACGAPTTPRTDPPARRCSAPDCGREHFPRVSPVVIVAVERGA
                     EILLGRSPHFPPGLYSTLAGFVDAGESAEQAVHREIFEETGLRIRAPRYFSSQAWPFP
                     HALMLGYQAEYAGGDIVCAPGEIEDARFFHVDALPPLFPIRYAMANQLLRDFCLRHGR
                     PWPPAQAAPTAA"
     gene            complement(33354..34547)
                     /locus_tag="P5537_05170"
     CDS             complement(33354..34547)
                     /locus_tag="P5537_05170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004373179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbfB/YjiJ family MFS transporter"
                     /protein_id="HRV77470.1"
                     /translation="MSDQKQRMKVLGAGIFSLMLALGVARFAYTPLLPLMQSQAGLGL
                     AEGGWLAAINYLGYLSGALLAASISDLVLKDRLYRIGMVVAVLTTLMMGLTTDFTVWA
                     VSRYLAGLSSAAAMLLGTGLILNWLIRHGHRHELGIHFAGIGLGIAGCSVAVAVMSLW
                     LDWRAQWYVFTALACVLLVPALAWLPAPDTSPVTKSGAPMHDNPPSPLFMRVFMASYF
                     CAGVGFVVSATFIVAIVNRLPGLEGQGSWSFLAIGLAAMPACIVWDFIARRTGALNAL
                     ILAAVLQIVGILLPVVVGGSLGAIAGALLFGGTFVGMVSLVLTMAGRYYPTRPAKMMG
                     KMTVSYGVAQILGPAVTGWLGETFGSYAGGLWFAAAMMAVGTVLLVALKIVDRRDAQA
                     AVGAA"
     assembly_gap    34558..34657
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            34705..38040
                     /gene="mscK"
                     /locus_tag="P5537_05175"
     CDS             34705..38040
                     /gene="mscK"
                     /locus_tag="P5537_05175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive channel MscK"
                     /protein_id="HRV77471.1"
                     /translation="MSLLRLLFLLLLPLLSMHAAAEAPPRPQPDELRARLQALAERKL
                     PEAEQRTAQQALEQAQASLASAEDYRRRLDALKQTLADAPAQIAEARRQLAALSTAAP
                     VAEPAADTPLARLEERLAEQEAALADWRRRLDEADGLVVGSRTGPERAQTEISTGQVR
                     MAEIETTLASGREAGRDGRPLGPERRDALAAEWHALDAQLTLRRQELAGNSGLIDLGL
                     ARQELARLQVARLEDAAHVLQDAISRQRASQAEQTVQALADVRADTSGDALLAREAAT
                     NEELSQYLLRATAHLDTLTRRNQKVSQQLDAINRSTAVIDEQIGVLQGSVLLSRILLE
                     QRRALPAPVADAGLADQIADIRLYQFEINKQREQLTNPAAHAERLLAGAPAGEADPTL
                     REPLLALLATRGELLERLNRELNAVLAQSITLQLAERQLLVSADRLRATLDKQMFWIP
                     SNRPLDLTWLQAVPGALAKQFGAIPWGSAIGELWAGLQARPFLFLPVLLVSLGLFARR
                     RWLREKLDSLHADIGYVRRDSQRHTPLAILLNLLLTLPVSLLLALGGIALQMDARGQN
                     AALGAALMQMAQAWLVFHTAHRLLTPGGVAERHFQWPVERVRAMHRNLRKLGLVVVAV
                     VAVVAVAERQPESLGSDVLGMLILLVGYATMAWLLGRGLLHTRLDDRLSPLRVFVGLA
                     LGLMPLALIGALVMGYYYTALKLTGRLVDTLYVLILWRLAEGVLVRALGVAAHRIDHQ
                     RAVARREAAEREGRAGADSEPAAVAEAPMLDIARINQQSLRLLQLTLLSGLAVALYWV
                     WADLLSVVSYLDNITLYEYASGSGEAAGVVPISLADLLGALVIAAIAFMLATNLPGLL
                     EVLVLSRLKLAQGSAYAITTLLSYVIVGVGIASTLGTLGVSWDKLQWLVAALSVGLGF
                     GLQEIFANFVSGLIILFERPLRIGDTVTIGNVSGTVSRIQIRATTITDFDRKEMIVPN
                     KAFITGQLTNWSLTDTVTRVTIKLGVAYGADLEATRRLLLRIAADNPRVLRDPEPLVF
                     FLNFGASTLDHELRVHVRELADRNAAIDEINREIDRRFREQGIEIAFNQMDVHIRSIA
                     DGREALLQSTPAVPPAPSSGLQG"
     gene            complement(38310..38696)
                     /locus_tag="P5537_05180"
     CDS             complement(38310..38696)
                     /locus_tag="P5537_05180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004356982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77472.1"
                     /translation="MYRDPRFSGLFQTLGGPAAKPPTLLQKVVGAVVMAGVFMLALTF
                     SVAFFAVLLTAGVAIWGWVWWKTRALRKAMRAQMDAQASAGGGRAGGYGPAGGNRGLI
                     IEGEVIREVEVEDEVRRDGQDGRRPS"
BASE COUNT         5884 a        14413 c        12858 g         5444 t
ORIGIN      
        1 cccaagccac cgggaccgga gcgacccgca tgaaaaaatt catccgcgac aacccgacca
       61 tcgccttcgg gctcggcctg ccgctgctgc tcgtcgcggt gttcctcgcc atctcgggca
      121 ttcccgcgct gctggtcgcg ccgccgcagt acgaggtgtt gtacgcgacc cactacaact
      181 tccacaacaa cgcgcacaac gcgatccaga tcgcggtcgt cggtgatcgc gtgcaggtca
      241 gctacgtcgg caacacgcag ccctaccaga ccccgcggct gtggcgcttc aacccgaaaa
      301 ccggcgcggt cagggaaatc gcgctgccct tgccggccgg cctcgccccc aacagcgggc
      361 gcccggtcga ggcggagaag acaccgagcg tgacccccat cgacgtcccc gacctcgccg
      421 agctaaaggt cgattcgtcg agcctggcgc cggatggcta caccttccgc agcagcgccg
      481 acagctacgg cggaaacgtc ttcgacggcc tgttctttgg ttcttcgcgc taccgagtcc
      541 aggccgagct cgtcaaggac gggcgcagca tccggctgcc caacaccgac ggcgcccact
      601 acggcaacac ggtccgcttc gtcggctggg tgctgccgtg acctggctcc tgctgctgat
      661 cgtgctggtc gtcctcgccg gcggctggtg gggctggccg ctggccgcgg cgttgttcgg
      721 cagccgcgcg atccatgaca agaccagcgc gctcggcaag atcgccgagt tgatgcgtgc
      781 ccatgacatc tcgccggccg aagtcgccgc ggtataccgc gatccgaccc tgatctcgac
      841 cgcggccccc aaacgcagca gcggcgagat tgcacggacg ctcttcatct acctcggcgc
      901 gatcttcatc ctcgccggca tcggcaccta catcggcatg ttctggaacc gcatgggcag
      961 cgtcatgcgg atcgtcgtca ccctcggcgt cggctatgcg ctgctggtcg tgctggtctc
     1021 ggcgctgcac gagaagaagt ttcccaggct cgtcctgccg ctgacgctgg cgacggcgtt
     1081 catgctgacg agcggctggt tcgtcttcat cgacgaggtc tttccgcgcg gcgacgactg
     1141 gcggctggcg gcgctcgccg tcttcggcac gatggcgatt catcagggcg tgctgtttcg
     1201 ccagtacgcg ctgagcgtgc tcgccttcac cgccctgtgc ttcgtctacg cctttctgtc
     1261 ggtcggcctc gacctgctcg acgtgccggc gggcttcagc gcgatcctgc tcggcgcctc
     1321 gctgctgctg gtcgccagcg gccttgaaaa gtcgccgcag cgcagcctcg ccgagtttgc
     1381 ctacctgatc gcgctgtgct ggttcaacgc cggcctgttc gaccgcgtcg ccatcgccgc
     1441 cgcggccgac tgggccgcgc tgctgaccgg cgcctcggtc atgtcggccg cctacggcct
     1501 gcacaaggac gggcggcaac tccggctgtc cggcctcggc tacctgatcg gctcggcact
     1561 cgcctacagc ggcctcttcg acctgctgcg ccagaccccg gtcgagctgc tctacttcgc
     1621 cgtcaccgcg gcgatgctct acgcctgcgt gcggctgcag agtcgcgcac tgctcctgac
     1681 cacggtgctc gcgatgctcg gtttcatcgg ctacttcacc gccgaacact tcgtggattc
     1741 gctcggctgg ccgatctcgc tggtcctcat gggcgtcgcc ttcatcggcg tcggcacgct
     1801 ggcaatgcgg atcaagcggc agatgtgagg gcgctggcct ggaaggggca gtaccggtcg
     1861 gccgcttcct cgctgtactg gcagaggatc ccttccacaa gcgcccgccc gacgagagac
     1921 tcgtgggcga tcttgccggg gtacgacgcc gcgcccttga ttgattcact ttcaatcact
     1981 atgatttttt cagcatcgca ttgattacac gaagcggctc ggcagggggt cgcttcccga
     2041 cccccgctcc cgaccgacga gcctacagat gacgcaagcc gcaaccaaag tgctcaccgc
     2101 ccatgtgccg ctcccgctcg ccgagaaggt cgatcagatg gccgcgaggc tggagcgctc
     2161 gcgcggctgg atcatgaagc aagcgctctc cgcctggatc gcccaggaag aggagcggga
     2221 ccgcctgacc caggaggcgc tcgccgacgt ggacgccggt ctcgtcgtag accatctcgc
     2281 ggtgcaggcc tgggccgaca gcctgggcac cgaccagccg ctgccgctgc cacgctgatg
     2341 gagctgaagt ggacccgcaa ggcgcttgcg gatctgacgc gcctgcatga gttccttgcg
     2401 ccggtgaaca ggcaggccgc cgcaagggcg gtacaggcgc tggccaaggc cccgaccatc
     2461 ctgctgagca acccgcgcat cggcgaacag ctcttccagt tcgcgccacg cgaggtgcgg
     2521 cggatcctgg tcgcgcagta cgaggtgcgc tacgagatcc gggactcggt catctacgtc
     2581 ctgcggctgt ggcacacccg agaggaccgc aactgaccca tgcccctcga cttcgccacc
     2641 ctcgacgccc tgcgcagcca ccaccccgcc tggcgcctgc tgcgctcgga ccatgcggcg
     2701 ctggtggcga gcttcctgca tcgcgtcttc gtcaccccca acgtgcgcgg catgccggcg
     2761 gcggacctcg ccgaggcgct ggaggacgag ctctacgcgc tgcgcctcac gcgcggcgag
     2821 gacgccttcc ccaaggcggc gatcgactac ctcgacgact gggccgcggc cgacaaggcc
     2881 tggctgcgca agtactacaa gcccggcacc gacgaggccc agttcgacct caccccggcc
     2941 accgaaaagg cgctcgcctg gctggcgcag ctgagcgagc gccagttcgt cggcaccgag
     3001 tcgcgcctgc tcaccctctt cgcgctgctc aagcagatgg gcgagggcag cgagaccgac
     3061 cccgcgcggc gcatcgccga gctgcagcgc aagcgcgacg agatcgacgc cgagatggcg
     3121 cgcgtgctcg ccggcgacat cccgctgctc gacgacaccg cgatcaagga ccgcttccag
     3181 cagttcatgc agggcgcgcg cgagctgctc gccgacttcc gcgaggtcga gcacaacttc
     3241 cgccagctcg accgccgcgt gcgcgagcgc atcgcgctgt gggagggcag caagggcgcg
     3301 ctgctcgagc agatcatggg cgagcgcgac gccatcgccg actccgacca gggccgcagc
     3361 ttccgcgcgt tctgggactt cctgctgtcg agccggcgcc aggaagagct cagcgacctg
     3421 ctcgaccagg tgctggcgct gcccgcggtg gccgagctca accccgacgc ccgcacccgc
     3481 cgcgtgcatt acgactggct ggaggcgggc gagcacaccc agcgcaccgt ggcgcagctc
     3541 tcgcagcagt tgcgccgctt cctcgacgac caggcctggc tggagaaccg ccgcatcatg
     3601 gacctgctgc acggcatcga gagcaaggcg ctggccctgc gcgccgcgcc gccgccggga
     3661 acggcgatgg agatcgccct ccccggcgcg gcgatcgagc tggcgctgga gcgcccgctg
     3721 cacaccccgc ccacccgtcc ggcgatcgcc gagctgcgca tcgaggccgg cgacgaggac
     3781 gtcgatccgc acgcgctctt cgagcaggtc acggtggaca aggcacgcct cgcccgccac
     3841 atccgccacg ccctgcagga ccgcgcccag gtcacgctcg ccgcactggt cgccgcgcag
     3901 ccactggagc agggcctggc cgagctgatc gcctacctgc agctcggcag cgacgccttc
     3961 accaccaccc tcgacgaggc cacgcccgag ccgatcgaat gggaggccag cgccaccgac
     4021 ggcagcaccg tcacccgccg ggcgcgcctg ccgcgggtga tcttcatgcg ctgagnnnnn
     4081 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4141 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnngatgg acgacgaaga cctcgccccc
     4201 ggcccggccg agcccgcggc ccccgccccg gcgcccgacc tgtcggtgct gctgatcggc
     4261 ctgctcaagg gcgtgctcta ccgcgaagcc gacgagcgcc agtggtccag cctgctgcag
     4321 ctgcaggcgc gggtgcgcga atacgtcgcc gtgctcaacc tcgagctggt gctcgacgag
     4381 gccgaaggct acgccttcct gcgcggccgc cccgagcccg ccgacgacga ccccgcgccg
     4441 cgcctgccgc ggctggtggc gcggcggccg ctgtcctacc cggtgagcct gctgctcgcc
     4501 ctgctgcgca agaagctcgc cgagttcgac gccggcggcg gcgacacccg cctggtgctc
     4561 gggcgcgacg acatcgtcga gctggtgcgc gtgttcctgc ccgaaggccc caacgaggca
     4621 cgcctgatcg accagatcga gacccacatc aacaaggtcg tcgagctcgg cttcctcgcc
     4681 cgcctcaagc ccaccagcgc cagcaccacc gcgcccgcca gctttgaggt gcgccgcatc
     4741 ctcaaggcct tcgtcgacgc gcaatggctc gccgacttcg acgcccgcct cgccacctac
     4801 cgcgccgccc tcgccgacgg caaggagacc ccgtccgatg acgcctgagc cgctgcgaca
     4861 cccccctccg atcacgcctg acgcgctgcg acacccccct ccgataacgc ctgacgcgct
     4921 gcgacacccc cctgtaggag cgccggcagg cgcgaacatc ggcgctcgag accaccacct
     4981 ggcctgggga aagccccgac cgatcgcgcc tgccggtgct cctgcgggcc tcgagaccgc
     5041 gtcaccaagg tccgccgcat gaacgacccg caatccctcg gcctcgactt cgtcgccgac
     5101 gacaccctct ccggctttcg cctgcagcgc ctggaggtgc tcaactgggg caccttcgac
     5161 cgccacgtgt ggacgctgca gctcgacggt cgcaacgggc tgctcaccgg cgacatcggc
     5221 tcgggaaagt ccaccctggt cgacgccatc accaccctgc tggtgcccgc tcaccgcatc
     5281 gcctacaaca aggccgccgg cgccgacacc cgcgagcgca gcctgcgctc ctacgtgctc
     5341 gggcactaca agtccgagcg caacgaggtc accggcgccg cgcgcccgat gggcctgcgc
     5401 gagcccggca gctactcggt gatcctcggc gtgttccaca acgccggcta cgaccagacg
     5461 gtgagcctgg cccaggtgtt ctggttcaag gagccacaag gccagccggc gcgcttctac
     5521 ctcggcgccg agcacgcgct gtcgatcgcc gcggacttct ccggcttcgg ccccgacatc
     5581 acccagctgc gcaagcgcct gcgcggcgcg ggcgccgagg tcttcgacag cttcccgccc
     5641 tacgccgcct ggttccgccg ccgcttcggc atcgacaacg agcaggcgct cgagctcttc
     5701 caccagaccg tgtcgatgaa gtcggtcggc aacctcaccg acttcgtgcg tcaccacatg
     5761 ctcgagccct tcgaggtcgg cccgcgcatc caggccctca tcggccactt cgacgacctc
     5821 gaccgcgccc accaggcggt gctcaaggcc cagcgccagg tgtcgctgct cgccccgctg
     5881 gtcgaagact gccaccgcca cgacgcgctc gccgccgaca tcggcacgct gcggcgctgc
     5941 cgcgaggcgc tgcagccgca cttcgccgcg cgcaagctcg ccctgctcga ccaccgcctg
     6001 gcgctcgccg ccgaggagtg ggcgcgcgcc gacgcccagg tcaagcgcct ggacgggctg
     6061 cgcgaggagc aggcgctgcg catcgacgcg ctcaagcagg ccatcaacgc caacggcggc
     6121 gaccgcctcg agcgcctcgc cgccgagatc cgcaagctgg cgcaggtgcg cgacgcgcgc
     6181 ctggccaagt cgcgccgcta tgccgagctc gccgcggtgc tcggcacccc cgccgccgcc
     6241 gacggcgagg ccttcgccgc ccagcgcctg cacttcgccg cggggcgcga ggacgcgcgc
     6301 agccgcgacg ccgagctgca gaacacgctc accgagcacg ccgtcagcct gcgccagggc
     6361 aagctcgaac acgacgcgct gagcgccgag atcgacagcc tcaggcgccg gcgcagcaac
     6421 atcgacgacc gccagatcca gatccgcgcc gcgctgtgcg gcgcgctcgg catcgacgtc
     6481 gaggacatgc ccttcgccgg cgagctgctg caggtgcgcg aggacgagcg cgactgggag
     6541 ggcgccgccg agcgcctgct gcgcggcttc ggcctcgccc tgctggtgcc cgacgcgcac
     6601 tacaaggcgg tggccgagtg ggtggacggc aaccacctgc gcggccgcct ggtgtatttc
     6661 cacgtccgcc cgccgcgcac cggcgagctg cccgcgctgc accccgactc gctggtgcgc
     6721 aagctcgcga tcaagcccga cagcccgcac tacgactggc tcgagcgcga gctcgcccac
     6781 cgcttcgacg tcgcctgctg cgccacccag gagcagttcc gccgcgagac gcgcgcgatc
     6841 acccgcgccg gccagatcaa ggaccccagc ggccgccacg agaaggacga ccgccacgcc
     6901 atcgccgacc gcagccgcta cgtgctgggc tggagcaaca ccgccaagat cgaagccctc
     6961 gaagcccagc gccgccagct cgaggcccgc ctcggcgagc tcggcagcca gatcggccgc
     7021 atcgacaccg agcgccgcgc cctcgccggc cgcctcgacg ccctcacccg gctggaagaa
     7081 ttcaccgcct tcgacgagct cgactggcac ggcgtcgccg gcgagatcgc cacgctggaa
     7141 gacgaacgcc gcgcgctcga agccgcctcg gacctcctca aggagctcgg ccgccagctc
     7201 gccgagctgc agcagatccg cgtcgacacc gagcgcgagc tcggcgccgc ccgcgaacgc
     7261 cgcgccaagg tcgagcagcg ccaggccgac gccgaggacc tgcgcgcgac cacgctcgcc
     7321 cttgtcgacg ccgcgccgat cgacccggcg ctcgtccccc agctcgaggc cctgtgcgcc
     7381 gaggtgctcg gcgagcatca actcacggtc gaatcgtgcg acaaccgcga gaaggaagtc
     7441 cgcgacctgc tgcagacgcg gatcgacgcc gaggaccgcc ggctggcgcg cctggccgag
     7501 aagatcatca aggccatgtc ggccttcaag cagcagttcg cgctcgagac cgccgagatc
     7561 gacgccagcc tggaggccgg cttcgaatac gagaacctgc tgacgcagtt gaaccgcgac
     7621 gacctgccgc gcttcctcgc gcgcttcaag gagctgctca acgtcaacac gatcaacgaa
     7681 atcgccaact tcaacgccca gctcgcgcgc gagcgcgaga ccatcaagga gcgcatcgcc
     7741 cacatcaaca agtcgctcgg cgagatcgac tacaaccccg ggcgctacat cgtgctcgaa
     7801 tcccagccca gccccgacgc cgagatccgc gacttccagc aggagctgcg cgcgtgcacc
     7861 gagggcgcgc tcagcggggc cggcgagggc gacgacgagc agtactccga ggaccgcttc
     7921 ctgcgcgtca agggcatcat cgaccgcttc cgcggccgcg agggcctctc cgaccaggac
     7981 cggcgctgga ccgcgaaggt caccgacgtg cgcaactggt tcctcttcgc cgccagcgag
     8041 cgctggcgcg aggacgacag cgagcacgag cactactcgg attcgggcgg caagtcgggc
     8101 gggcagaagg agaagctcgc ctacaccatc ctcgccgcca gcctcgccta ccagttcggc
     8161 ctggagtggg gcgcggtgcg ctcgcgctcg ttccgcttcg tcgtcatcga cgaggccttc
     8221 ggccgcggct cggacgagtc cgcgcaatac ggcctgcgcc tcttcgagca gctcaacctg
     8281 cagctgctga tcgtcacccc gctgcagaag atccacatca tcgagccctt cgtcgccagc
     8341 gtcggcttcg tgcacaacga gggcggcagc gcctcgaagc tgcgcaacct gtcgatcgag
     8401 gagtaccgcg cgcagaaggc ggagatgcgg gccgccgccc aggccgcgcc gcgcgccggc
     8461 ggcgccgcat ccgcgtcatg agctggagca ccgtgccgga cctgaaggcg caggtgatgc
     8521 gcctgtggga gcgcggcgag ctgctgcgcg aggggctgaa cgccgccacg agccgcttcc
     8581 cgctgcgcct caccctgaag acgcccggcc cggatgacat cacccgccgc ttcgacgccg
     8641 tgcgcgcctg gatcgcggcg atctcggcca cgccccatgt gcgcctcgaa tggcaggaaa
     8701 cccgccaccg cgtgcagggc agccagcgcc tgcccgcgag cgcctgggtc gaccgcctcg
     8761 acgacgccct ggcctggatc ggcaagcgcg ccgagcacgc gcgcttccgc gcgctgcacg
     8821 ccgagactgc gtcgcgccag cccctgctgc tgccctggct ggcgaagcgc ccgctgcgcg
     8881 cgctcgagct cgccgccgag tggtcgcgcc tgctcgacgt ggtcgcctgg ctgcaggccc
     8941 acccgcggcc gggcgtatat ctgcgccagg tcgacctgcc cggcatccac accaagttca
     9001 tcgaatccca gcgtggcgtg ctcgccgagc tgctcgagct cgccctgccc gcggcggcga
     9061 tcgacccggc gcgcaccggc gcgcagcagt tcgccgcccg ctacggcttc ctcgacaagc
     9121 ccgtgctgct gcgcctccgc atcctcgacc cggcgctgca cctgctgccc ggcgcgccct
     9181 gccccgacct cgccctcgac gccgacagct tcgcccgcct gcgactcgac gtggcgcgcg
     9241 tcttcatcac cgagaacgag accaacttcc tcgccttccc ccgcgtcgac aaggccatcg
     9301 tgatcttcgg cgccggctac ggctgggagg cactggcacg cgccgagtgg ctgcagcgct
     9361 gcccgatcca ctactggggc gacatcgaca ccaacggctt cgccatcctc gcccagctgc
     9421 gcgcccgctt cgcccacgtc gagtccctgc tgatggaccg cgccaccctg ctcgcacacg
     9481 aggcgctgtg gggccgcgaa gacagcccgc gcccggccga cgtctcgcgc ctcaccgccg
     9541 aggaacgcag cctctacgaa gacctgcgcg accaccgcat ccgcccgtcc ctgcgcctgg
     9601 agcaggagca catcggcttc ggctggctgg aaaaatggct gaaaatcgtc catgtgatgg
     9661 atgattttca gccatcggat ggttgatctt catccaaggc gtcccgggaa acggctgctc
     9721 agaacgacca tcgcccttcc tgcccatctt gggcctgcgc catctccaag acaccgaacc
     9781 cgaacgcatc cagcgcggca gcgtctgggt accggacggc ttcgtgtcag cagtggggaa
     9841 agcgcaggcg ttcgcgttaa agtccgatct gtccgtctac cccaccgctt atgacgcccg
     9901 aagcccacgc ccggaactgc atcgacgccc gtctgcaaca ggcaggcgaa ccggccagcg
     9961 cgctgcccaa acgcatccga aaccaagctg cagccacgag ttctgccaga aaggctgacg
    10021 ataaccgtca ctgcccgtcc aaggtccgtt catgaaaatc gaatccatcc gtctcaagaa
    10081 cttcaaggcc ttccgcaatg tgcacctgaa ggacatacct tcctttctgg tggtcgtcgg
    10141 cgcaaacggg tcggggaaat cgacgttgtt cgatgtcttc ggcttcctgc acgactgcct
    10201 gaaaggcaat gtccggcaag cgctcgacaa gcgcggccgc ttcggcgaag tgctgagccg
    10261 gggttgcgac ccgaagaagg acacgctcct catcgagttg cagtaccgca tggagatcac
    10321 tggcgtcgag cggctggtga cgtactcgtt ggaaatcggt gagcggcaag ggatgccggt
    10381 ggtctgcaag gaacttctgc gttacaagcg cggccgctac ggaagtccct accacttcct
    10441 cagctttgcc gagggcgaag gctacgcgat caccaacgag gaagacttca acaagaccga
    10501 cgaggaactc gaccgcgaaa cccagcgggt tgcgccggac acccttgcga tcaaaggtct
    10561 ggggcaattc gagcgtttca aagccgccaa tgccttccgt agcctgatcg agaactggca
    10621 cgtgtccgat ttccacatca gcgccgcgcg agggcgcaag gacgcatcgg gcgaaatgga
    10681 gcacctgtcg gagaccggcg agaatctacc cttggtcgct cgttacctgc atgagcagca
    10741 tgccgagatc ttcagcaaaa tccttgcaac gatgaccaaa cgggtacccg gcgtgacttc
    10801 ggtcgaaccc aagctgatgg atgatggcta cctcacgctg cgttttcagg atggctcgtt
    10861 caagacgcct ttcctcgacc gctacgtgtc cgacggcacc atcaagatgt tcgcctatct
    10921 ggtgctgctg cacgatccgg agccgcaccc cttgctatgc gtggaagagc cggagaacca
    10981 gctttatccg cagttgatgc ctgaactcgc ggaggaattc cgtagctacg ccaatcgtgg
    11041 cggacaggtt ttcgtatcca cgcattcacc ggatttcctg aacgccatcg aactcgacga
    11101 ggtgtattgg ctggtcaagc aacagggcta ctccgagatt caccgggcgc gcgacaatgc
    11161 acaaattgcc gcctacgtcg ctgaaggtga tcaactcggc tacctgtgga agcagggctt
    11221 cttcgacggg gtcgatccgc gatgagggaa ctcgtgtttc tgctggaaga gccgtcggcc
    11281 aaggccatgc tggaatccct gcgcccccgg atgctgaagc aagacaccct tttccgctgc
    11341 atcccgttcg aaggcaagca ggatctggag aaacaactga ctcgccggat tcgtgcgtac
    11401 cagaacgaac gcgcccgctt catcgtactg cgcgatcagg acagtcaccc cgactgcacc
    11461 gcggtgaagc aaggtttgct cgatctgtgc gataagtccg gcaagtttgc gcgatgcctg
    11521 gttcgcattg catgccgaga gctcgaggct ttctatctgg ccgatctgca ggctgtcgaa
    11581 cgagccctcg agatcgacgg attgactcgg catcagaaca gcaggaagtt ccgatccccg
    11641 gacggactcg gcagccccag ccgagagttg aaaaccttga cacgcaatcg ctacgaaaag
    11701 gtcgctggct ctcgtgcgat cggcaaacac ctgcaactcg acaatgcccg ctccgcgagc
    11761 tttcgtaatc tcatcgcagc catccggcgt tgcgaagacg aactcctgcg ggaagcagtg
    11821 tgagtccgtt tcttggtgcg ccttatccga tttccatgat ccgcggccat cgtcaagacg
    11881 gaaacccgtg tgagctcgcc gctcgtcaga gtcaccccgc caaggggaag gcggcgggcg
    11941 gcgagtttcg catgagtccc aagtacggac cgtacttcct gtggccggag agtctcctcc
    12001 cataactgag cgcttcccgt ctgcaggttc gacagttcag cacgcaagtg cttgtttcga
    12061 ctgaatcaca catccccgga aatgccacca cacgacgccc gcccccacgg cccggccacg
    12121 actcgtccct gaccaccctc tctccgcgag acatcttgaa aagcgccctc ttcgtcgact
    12181 tcgacaacgt ctattccggc ctgcgcaagc tcgacccggc catcgccgac cgcttcgccc
    12241 gccagcccct ggagtgggtc aactgggtga tcggcgagct cgagctgccc gaccacgccc
    12301 ccgccggcgc gcgtcgccgg ctgctggtgc ggcgctgcta cctcaacccg caggcctacc
    12361 agcgcttccg cccgtccttc aacctcgccg gcttcgagat catcgactgc ccggcgctga
    12421 cgagcgaggg caagaccagc accgacatcc acatggtgct cgacatcatc gacctgctgc
    12481 agcacgaggc ccgctacgac gagttcatcg tgttctcggc cgacgccgac ttcaccccgg
    12541 tgctgcgcaa gctgcgccgc tgggatcggc gcacgacggt gctggcgatc ggctttccgt
    12601 cggcggccta tcgcgcctcg gccgacctgc tgatcgaccc cgacgagttc gtccgtaacg
    12661 ccctcggctt ccgcgacgag gacgaggcgc ccgccaccgc cgccgacaac gcggacgtgg
    12721 acggcccgtc ggccgtggcg agcgcacgcg ccgcgcaggt gatgccggac gcacccccca
    12781 tcgaccccat cgactccgcc gccctcgacc gcgccgtcgc cgaggtcgtc gccaccatgc
    12841 gcgccgaggt cgcgcgcgcg accgcgcccg tgccctgcag ccgcctggcg agcctgatca
    12901 cgacgcgcca ccccgccctc gccgccgact ggaacggcaa gggcagcttc cgcaagttcg
    12961 tcgacagcct cgagctcgcg ccgctgcgct tcgactggag caacagcggc ggcttcgtct
    13021 tcgatcccgc ccgcgccggc accggcatgc aggacggcag cgccaccccc gactggggcg
    13081 aggaccagga catcctgccg ctcgccatgc agatccacga ggtctccggg gtcccgctgc
    13141 tcggcccggt cgagtatcgc gcgctgttct cgatcatcga ggacgacgcc ggccgccatc
    13201 ccttcgacct caaggagacc ggcaagcgcg tgcgcgaccg cctgcgcgag gccggccacg
    13261 gcggcagccg gctcgacgtc aactggatcc tgcgcggcct gctgatgcgc ggccacgcct
    13321 tcggcgaagg ccaggaccgc gcggcgacgc tcgccaccaa gacggcgaac aacgtgcgct
    13381 cgctctgcct gcgcgagcag atgatcctcg accgcgcggc cgagacggcg atcgcgcgct
    13441 ggttcggcac cagcccggac gcacgccgca tgggccagta gcagggacgg gacgggcgtc
    13501 gcgcatccgc gcgtcttgcg tgcgcgcgac ggcacaccaa caatgagacc tcacgctgaa
    13561 accccgaggc gaggatcatg aacaccaaga cccgcagcgc cctgcgcgcc agcctgaaac
    13621 aggaagatgc cgcgctcgac gagcgcctcc ccgaggcgga gtcccccgcg gcaaagactc
    13681 cgcccgacgc tccggtcgcg gcacccgagc gcaagccgcg cgcccgccgt gcgccgccgc
    13741 aaggcaggac gccggcgaaa acggtggcac ctggcatcgc gcgcgtcgct acggcagccg
    13801 cttccgcgcc cgctgcgccc cccgccaggg cagcctcctc catccctgcg gagccccgcc
    13861 cgcgcagcgg gaccgccacc caagccgcaa agccctccaa gcccaagacg gagaagcgcc
    13921 agcgcgcatc cttcacgctg gctgcgagcg acctgcaccg cctcgatgcc ttgcgcagcg
    13981 ccatgaaagc cgccggccgg ccggcgcgca agtccgagct ggtgcgcgcc ggcctcgccg
    14041 cactcacggc cctcggccat gccgatgcga tcgcgctgct cgacgcgctg ccgcctctga
    14101 agcgcaccgc cggcaagggg gatgagaagg gcaaggccgg caagaagaag tccgcgaagc
    14161 gcaaggccgc cgcccgctag cgcagatccc ggcatctccg gaagctcccc acccatggat
    14221 cccgacctcg ccaccgagct gttcgaatcg ctcggcctcg atgccctgct gcccgagccc
    14281 ctcgccgcct ggcgcccgct gctcgccgaa ggcatggcct tcttcctcgg gcgcctgcct
    14341 gaaacccgcc tcggcgcgat cgtcacagaa cagctcgcgc tcgccgagag cgcctctgcg
    14401 gccgcgcgcg ccaccgcgct gctcgcgcac tgccccacgc tgcacaagct cggccaggtg
    14461 gtcgcacgcc agcccggcct cgacgccgaa ctccgccgcc acctgcaggc actcgaatcc
    14521 ctgcccgcga atgtggaggc cgataccctt caccggcaga tcgcggccga gctgggggcc
    14581 gaccacggcc tgcacctggc cgaccgcgcc ctcgccgagg gcagcgtcgc ggtggtgctg
    14641 cccttctcgt ggcggcaggg cggacgcagc cacgagggcg tgctcaaggc gctcaagccc
    14701 ggcatcgccg accggctggg cgaagagctc gccatcctgc ccgcgctcgg cgacttcctc
    14761 gagggccggg gcgcggagct cggcctgccc gccatcgact accacagcca cctcgccgcc
    14821 gccggccgcc tgctcgtgca ggagatccgc ctcgaccgcg aacaggccaa cctgcgcgcc
    14881 gcggcggcgc tgctcgtcga cgatgccgac gtcttcgtcc ccacgctgct gccctggtgc
    14941 acgcctgcgc tgaccgcgat ggagcgcatc gacggcccca agctcagcga cgccgcgctg
    15001 tcgacgcacg agtcccgccg cctcggccgc gcgctcgtcg gcggcctgct cgcgcgcccc
    15061 ttctggtcgt gcagcgagaa ctcgcccttt cacggcgacc tgcacggcgg caacctgctg
    15121 ctcgctcccg acggccgcgt ggccgtgctc gactggagcc tcgtcgcgcg cctgagcaag
    15181 gccgagcgcg aggcgctggt cgaagtcgcc ctcgccgccc tcgccctcga tccgtcgcgc
    15241 atcacggccg gcctcgccgg gctgggcctg cgcgacagcc gcagcacggc gatcggcgcc
    15301 accgtcgagc gcgcgctcga caccctggtg cgcagcggcc gcccgctcgg cttcgactgg
    15361 ctggtcggcc tgctcgacgc gctcgcgctg cagggcgcga gcggcttcgg cgagcagctg
    15421 gcggtgttcc gcaagagctg gctatcgctc gccggcgtgc tcggcgacct cggcggcggc
    15481 cacgacaccg acctgccgct gctcggcctc ggtctgcagc gcttcaccgc cgagtggccc
    15541 gcacgcctgc tcgccccggc cgactcgcgc gccttctcca cccacgtctc caccgccgac
    15601 ctgctgcgcg cagccgcgga cgcctggccc gccggcctgc gctactggct aaggctgctc
    15661 gggcacggac actgaacgag ggctcatgcg ggagcggcac cggccgcgaa ggccgcactc
    15721 cgacgggcac ggccgcgact gcgagcacag cgccggcttc agcccggcga ggatgctgcc
    15781 catcttcaat cctcgatgag cccgaccacc gcggcgacca ggcgcgccac ctcctcctgc
    15841 gccggcgcgg cagcccgccc gaggccgaac accgaggtcc cgcgcaccgc gctcagcgcg
    15901 taggcgctgc gctgcgacag cgcggcgtcg agcaccggca gggtgaaatc gcgcagcaca
    15961 tcgagcacgt cggccgacag cgcggtgcgc gtcacgcggt tgggcagcaa ggcaccgcgc
    16021 aggccggggc ggctgcgctt gcgctcgagg atcaagcgct cgatgccgcg cgtcgcccac
    16081 aggtcggtcg gtcccggcac caccggcacc agcgcgatgt cgcagagctc gagcgcgctc
    16141 atcgtatgtg cgtgctcgat cgagggcggg cagtccatga ccaccacgtc caccttgttg
    16201 gcgaccgggc gcagggtctt ggccatcctg tcggcgctgc cggcgaggcg caccacctgg
    16261 gccgggaaag gcgcctcggc gggcgcggac tcggcccagc gcgaggcgct ctcctgcgga
    16321 tcgaggtcgg ccagtgccac gcggtagcct tcgagggcga ggccggcggc gagctgcatg
    16381 gcgaccgtgg tcttgcccga accgcctttc tgggagatca gtgcgatcag cgtgggtgcg
    16441 ctcatggtcc atcccgtggt ggtgatgccc gacagtctag ccaatcggcc gtccgccgtg
    16501 gctccatggc acgccgcgaa ggcattcggg caaaggatga gcggagaaat attgcgtcgc
    16561 aacaaccgcg gcgaaatcct ttgctacaat tcggaccttc tgcaacaggg tttccagcca
    16621 tggcgcgaga gatcgagcgc aggttcctgg tccgcgacgt acggatcctc gacggacgca
    16681 ggggcgagca catcatccag ggctatctcg ccaaggagat cggctcgatc tcgacgcggg
    16741 tgcgtattcg cggcgagcgt gcctacctga cgctgaagtc gcccaagcag ggcttcagcc
    16801 gcgacgagtt cgaatacccc attccggtcg gcgacgcccg ccagatgatc gcgcagcatt
    16861 gcgccgggcg ggtggtgcgc aagacccgct acctggtcga tcacgcccac cacgtcttcg
    16921 aggtcgacgt cttccagggc cagcacgccg gcctggtggt cgccgaggtc gagctgccgc
    16981 acgagcaaac cccgctctgc ctgccgcact gggtcggcga cgagatcacc cacgactcgc
    17041 gctacggcaa cttcaccctc gccgagcagg ccgccctgct gcacgctgct gcaacggccg
    17101 cgatcgcggc ccctgcggct gtcgcgaagc cgatcctcgg cctgccggtc gcgcattgag
    17161 gtctctccgc ggccgcgcgc gccggccgcn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17281 nnnnnnnnnc cgcagcggcg ccttcgacgt cgccgcgttc aggcgccagc ctgcagtcgc
    17341 atcgcctcac cggtctcgtc gaaagtcatc gccgctcgtc tgcccgccgc gttcgcggca
    17401 agccagaccg tcgccgccgc gacgtcgagc ggacgcgcaa acagatagcc ctggccctcc
    17461 tggcagccga ggtcgccgag gaccgcatcc tgcccgtcat gctccacccc ttcggccacc
    17521 gtgcgcagtc ccacgctgtg cgccatgcgc aggatggcct cgacgatggc cgcgtcctgg
    17581 tgattggtgg cgagctcggc gacgaagctg cggtcgatct tgagcgccga gatcggcagc
    17641 cggcgcagca gggtcagcga ggaatagccc acgccgaagt cgtcgatcgc gatcgaggcg
    17701 cccatgcggc gcagcgcctg cagcaggccg ttggcggccg gaccgtcggc ggtgagcgcg
    17761 ctctcggtaa gctcgacctc cagccggcag gcgtcgaccc catggcgctc gaggatctcc
    17821 acgatgcgct cgacgagctc gggacgcagc tgcgccggcg acacattcac cgcgatgcgc
    17881 ggcacctgca gcccggcacg atcccaggcc gcgagctgcg ccacggcgag ctccatcacc
    17941 gctaggccga gctcccagat cagcccgcag tcctccgcga gcggcacgaa gcggccgggc
    18001 gcgagcaggc cgaggcgcgg atggcgccag cgcaccagcg cctccatgcc ggcgaggctg
    18061 cggtcctcca ggcacagctg cggctggtag tgcagctcga gctggccggc cgcgatcgcg
    18121 gcacgcagct ccgactccac ggtcatgcgc tcgaccgcgc gcgcgttcat gtgctcggag
    18181 aagagctgat ggcggttccc gcccgactcc ttggcgtggt acatcgccag gtcggcatgg
    18241 cgcagcagcg actcctcgtc gtgcgcctgg aagggataga ccgccacgcc cacgctgcca
    18301 cccacgcgca gggcatgccc gcgcacctcc agcggccggg tcacgatgtc cacgaccttg
    18361 gccgccaccg cctccgcgtc cgcgacctgc cacaggtctc cgagcacgat cgcgaactcg
    18421 tcgccgccga ggcgggccac ggtgtcggac tcgcgcaccg cccggctcag gcgcagcgcc
    18481 atctcctgca gcagggcgtc gccgaggtcg tggccgaggg tgtcgttgat ccacttgaag
    18541 cggtcgagat cgaggaacag gacgccgagc aggttgccgc tgcgctgtgc gctgcgcaca
    18601 ccctggtgca ggcggtccat caacgcggcg cggttgggca gcccggtgag cgcgtcgcgg
    18661 gtggcgagct gcatgatgcg cgcctcggcc tcgtggcggc gggcgacctc ctcctcgagc
    18721 tcgcccacgc gctggcgcag ctcgagctcg tcggtgacgc tgcgcgccag caccgcgagc
    18781 gcctcgcgcg cggtcgcgcc gagacggcgc ggccgggtgt cgagcacgca cagcgtcccc
    18841 accgcctcgc cgcccggcat caccagcggc atgccggcat agaagcgcac ccccggctcg
    18901 ccgcgcacca gcgggttgtc ggcgaagcgt gggtcggcgg tggcgtcctc gacctcgaag
    18961 aggccctcgc ccaccagcgc atgcgcgcag aggctcaccg tgcgcgaggt cgtctgcatt
    19021 tcggtgccca cgcgggcctt gaaccgctgg cggtggctgt ccaccaggct gatcacccct
    19081 accggcacct cggcgatgcg cgcggcgagg cgggcgatcg catccagcgc gggttcgggc
    19141 cgggtgtcga gcacctgcag ctgccgcagc cggcggcagc ggcgcggctc gtcgagcggc
    19201 agcggcggca tccagctcgc cagctgggcg agcagcacct tggtgtcctc ggccttgtcg
    19261 aggaagacat cggcgcccgc ctcccggcac accgcctccc agggatcggc ggagcggctg
    19321 ctcagcacca ccacgcgcgg cgcgaggcct ggggtggcgc gcacccggcg cagcaggccg
    19381 atcccgctgc cctcggaaag agagagatcg agcagcacgg tgtcggggcg ctgcgcctcg
    19441 atcagcgcaa aggcgtcgtc ctcgccggcg gcgctgccga ccacgcacag ctcgggatgg
    19501 gcggcaagca gccggaccag gttgtcccgc aggagcgggg agtcttcgac gatgacgatg
    19561 cgcatgatgg cggttccacg ggtagatcca acgtcaccca tgttccgctc ccgcaccccg
    19621 cccccacagc ggcacctcgc cgatgcaggg gtcggcgggc cgccgatcat gatgtagggc
    19681 gatgacctac acaggaaccc gcgtgcttgg cgcagcggcg ccgccgcccc gccgccggct
    19741 ttcgcccgcg acacctcccg ccctcgccct cagccgcccc gatccaccag tccgtgctcg
    19801 gaacagtagc gcgccatctc cgccgtgttg gcgagcccgg tcttgtcgat gatgcggctg
    19861 cggtaggtgc cgaccgtctt caccgacagg tgcatggcct cggcgatctc gctggcgctg
    19921 cggccggcgg cgatcagcag cagcacgcgg tattcctgcg ccgacagcgt ctcgtgcggc
    19981 gcgcgcgccg gcgcctcgcc cgagagcagg tcggcgaggc gggcggcgag gtcggagctg
    20041 atgtagcgct ggccgccgcg cacgcgctcg atcgcggcca ccagctcggt ggtcgcgtgc
    20101 tccttggtca ggtagccggc ggcgccgagc tgcagcgcac gcgccgcata ggccgcctcg
    20161 tcgtgcatgc tcagcaccag cagccgggtg cgcggcgcgg cgcggtgcag ccgcacgagg
    20221 ccctccagcc cgctggtgtc gggcatcgac aggtcgaaca cggcgagctc ccactccgcc
    20281 gcgcgcacct gctcgagcgc ctgcgccagg caggaggctt caccgatcgc ggcgtcgggc
    20341 cagcgctgcg tcacgagctg gcgcacgccg aagcgcatca ccggatggtc gtcgacgatc
    20401 agcagcttca tcctccgtcc tccccggccg cgcccagcgg taccctcgcc tcgatcctca
    20461 ccccgcccgc ggcgcccgca ccgatgcgca gctcgccgcc ggccagcgcg gcgcgttcgc
    20521 gcatgctcag cagcccgagc gaggaacgcg cctgcggcgc catgccgacc ccatcgtcct
    20581 cgaccgccag gcggtactcg ccctccaccg cctccccgtc gacccgcacc cggcccgcct
    20641 gcgcgtggcg ggccacgttg gtgagcgcct cctgggcaat gcggtagagc tggttggcct
    20701 ggttcgcgct caagcgcccg gcatccgcga gcgtggcttc gcagctcacg cccgtgcgct
    20761 cggcgaactg acggcaggcg aggccgagcg ccgcctccag gccgaggtcg tcgagcaggg
    20821 gcgggcgcag cgctgccgag atccgccgca ccgtggcgat gccctcgccg agcacggcct
    20881 cgatctgcgg ccagtcctgc tcccgcccgg gcgccccctg cagcgcacga tgcaccatca
    20941 tcttgagcgc ggtgagcagc tgcccgagct gatcatgcac ctcgcgcgcc agccgcctgc
    21001 gctcgtcctc gatgctgcgg tcgaggccgt gcgcgaaggc ctcgatctcg ccgagcgcct
    21061 gctgcagctc ggcggtgcgt cgggcgacgg cgtcctcgag gcgggcgttc gcggcaatca
    21121 gcgccacctc cgcgtcaatg cgacgccgcc gctcgcgctg cagcaggctc caggcggcaa
    21181 ggatcagcgc aacgccgctc aagggaagca ggaaattgaa gaccgacgca cgcgtccgca
    21241 gcgcgtcgac gctgcgatcg cgcgcctcga tctcggcgcg cagcatgacc tcgatggcgg
    21301 cgaagcgcac gcggatccga tccatcgtgt cgcggccctc ttcgaggcgc cgcctccacg
    21361 gcgagtcctc gtcggcgtag gcacggcgat cggcgatgtt gcgctcggcg agcgcgacgc
    21421 ggtggtcgat cagggtccac agggtgtcga ggcgggcctg cggccggtcg gcgagcatcg
    21481 cgcgcagcgc ctcgaaggtg tcgtccagcc tgcgcatgcc gatctcgacg gggtcgagat
    21541 agtgctcgtc gccggtcagc acgtagccgc gctgcccggt ctcgacgtcc ttcagcgccg
    21601 acatcacctc ggcggcgagc agcaggccgc tgcgcgagcg cgagcgcgca tcggtgacgg
    21661 cctcgagctc gtgcaggctg gcctggctgg accaggcgag cgccacgaac aacgcaagac
    21721 cgaacagcat caacaatgtc gcagcggggg tgcgacgcgc tggcgaaaga caggaggcat
    21781 cggtaaagga tgtggcacgg gccacgcgca tgaccattcg gagcaagaat gatgttaaac
    21841 gaatcctcct cgcccacgca ccctcgatct cgcctgccct ccgcgctgcg acgacaaggt
    21901 tcctcagacc agaacccggt aatagccgta gatgttcctc gaggcgtagt ccggaccgtc
    21961 cttccacgaa tagcggatct tcttgtcgcg ctggcggatg tactgcccgg tcgtgttgcc
    22021 atcgaccgac tcgagctggt tgttgtcgta atcgattgcg gtgaccacga agtgatggtg
    22081 cgccttcggc accacggcga cgtcgcccgg gcggatgttg cggtccccgg ggacgtactg
    22141 gatctgatag ccgctgttac ccttcatcct gccgccatac agggtccagc tcacgtcaac
    22201 gcccgcgtaa tggagcacgt ggcaggcgaa gatgccgcac cagtgccgaa tcccgccgcc
    22261 gacgaaggcg ccgctgccga gcgtggccag cgtcttcttc gcctccgcca gggtcggcac
    22321 gatctccgta ccggcctctt cgaagaagaa gacgagctct tccggccagg gcttgtattc
    22381 gccgggcgag gcccaccacc gggcgacgta aacgatatcg ctgcgtattg tcatcgcagc
    22441 ctcccgaact gcagggttgc cgccatgccg acggcagggc cgggtgccac gccggatcac
    22501 gctccgctcc ggcacccgaa gtcaggcccg cctccaccac ccgggtccga tttcaacata
    22561 gctcatcggc cggagccttc aagacgcgcg cgcggacggc ctgtcgatcg tcggacgctg
    22621 cgcgccggac atcgctcagc gcggcccttc ggcacgcatc gcctcttcgc aatacggcgg
    22681 cgtgccgtcc ttgcggcaga aatccttgag cttgccgagc gactcgcgat agaacacgtt
    22741 ccactcctcc tgggtggtga agcgcgccga cagcgcgtag ttgcagcgcg catgcaggtg
    22801 gttgagcgcg cccacctcga ggccgaactg ctcgctgaac acacggcgca gctcctgcgc
    22861 ggggatgcgg gtgttcatcg ccgcggcgtc gtagagcgag aacttctcga agtccgcgtc
    22921 ggtgcagggc ggttgcgcgg cctgcgccgt accggcgagg gcgagcaggg ccaggatgcg
    22981 ggcggcgggt tgcagcagtt tcatgacgga tctccagtga acaggatggc ccggccacat
    23041 ggctgggcag gaaggcaggt cggccggcgg accgcggtgc tcatttgcca tgggcggcca
    23101 gcacgcccgc ggtctcccgc cggcgcgcga cgaacaccag gccgagcgcg ccgaagttca
    23161 tcgtcagcgc atacacgacg gcgccgaccg cgagctcggg ctggcgcagc agcacgatgg
    23221 cgacgaagat cgccagcccg gcgttctgca ggccgcactc catcgccacc gcgaccgcgt
    23281 ccctgcgctc ggcgccggcc agcatcacca ggccgtagcc caggcccatg accgcgaagt
    23341 tgagcaccag ggtcgccggc cctaccgaca gcaggttggc gaggatggtg tgctggtgcg
    23401 acacgaaggt ggcgaccacg atggcggcga agaacagcgt ggcgacccgg gcgatggccg
    23461 gctcggcgcg tgcggtgaag gcgggcgcgc ggagccgcag cagcatcccg gcgacgatcg
    23521 gcagcgtggt caccaccagc acgctgccga tcaggcggcc gaccggcagc tcggccagca
    23581 cgccgccatc cgcgccgaag acgccctcgc cgaaggcggc gagcaccgcc ttgaccagca
    23641 gcgggaaggt gagcagcgcg gccaggctgc tgatcacggt gaggctcagc gacagcgccg
    23701 cgttggcgcg cgcgaggtgg gtcaggaagc ccgagctcgc cccgcccggg caggccgcca
    23761 gcaccatcag ccccatgccg agcagcggcg gcaggtcgaa ggccagcacc accgcgaggg
    23821 cggccagcgg caccagcacg agctggccga cgaggccgat cagcagcgca cgcgggcgca
    23881 cgaacacgcg gcggaagtcc gcaccctgca gcgccagtcc gaccgagaac atgatgaagg
    23941 cgagggcggc gggcaacagg acatcgatgt tcatcgaggc gacctagagg aaggagacga
    24001 agacgatccc tgccgcggcg agcaggccgg tgcgtgtgcc ggcacgcgcg gtgtcgacca
    24061 gcagggcgtt gagcgccggc ccgccctcgg cgcggccgaa gcgccacacc agcggcgcca
    24121 gcgcgggcgc gccgacgaga ccgaggatcg cccccggcac gccgctcgcg gccatcagga
    24181 cgagcgccgg gatgggcagc agcaccagca gcgcgaaggc gcggcgcgcg cgcggcgcgc
    24241 cgagcactgc ggcgagcgtg cggcgcccgg cgcgcaggtc gccggcgagg tcgcgatagt
    24301 tgttgaccag cagcacggcg gcggcgggcg cgcccaccgc caggccggcg agcaggtcga
    24361 ggtggccgac cgcgcgcgac tgcagccagt ggctgccgag caccgcgaac acgccgaaga
    24421 agagcagcac gaagagctcg ccgagcggcg agtgcgagat cggccgcggc ccgcccgaat
    24481 acgcccagcc cgccaccagc gaggccagcc cgatcgccag gatcaggccg ccgccgacca
    24541 cgcacagcca ggcgccgagc agcagcgcga gcagcaggca gagcagggcg ccgcgcttga
    24601 cctcggcggc gctcgcccag ccggccagcg tgacccgcag cggcccgagg cgctcgggcc
    24661 gatcggtgcc gcgctcgaag tcgaccgcgt cgttgtagag gttggtgccg atctggatca
    24721 gcagcgcgca ggccgcggtg gcgagcagca ccgcccacgc cagctcgacg ccgtcggcga
    24781 cggcgagcgc ggtgcccagc atgaccgggg cgagcgccat gcccagcgtg cgcggccgga
    24841 tcgccgccca ccacacgccc agcgtgccgg ggcgaggcgg gaggggatgc agcggcgtca
    24901 cgcgctgcct cgacgaaagg caagggcggg cacgatcacc gatcgcgggg gcagggcctg
    24961 cggtgcgagg aagtgggaga agaacatggt ggaagacgct gcgaggaccg cggattatcg
    25021 catagccggc gcgccccacc cgcggaccgg ccgcactgca ctatgctggt cgtgaagaca
    25081 tgcccgcatt tcctgccgga ggccaatcat gaagcagttc gcgcccaccc tgccgccgct
    25141 cgcccgcgcc gcggtcctcc tcatctccgc agtcctggcc ggcggggccc tcgccgcgcc
    25201 gcccgggccg ttgccggcac tgaacatcga catcgaggac acctcggtct cgggcatctc
    25261 gtcgggcggc ttcatgtcgg tgcagatgca ggtcgcgcac tccggcatca tccgcggtgc
    25321 cggggtggtt gccggcgggc cttactactg cgcgcaggac agcgtgatga aggccactac
    25381 cgaatgctcc tgcaccggcg agccgacgct gtcgtgcaag gtcgccgacg ccagcgcggc
    25441 ggtgcccgag ctggtcgcgg ccacgcgcgc cttccatgcc gaaggccgta tcgacgaccc
    25501 cgcgcagatc gcccgccagc gcgtggtgac cgtggtgggc gggaaggaca ccctggtacc
    25561 cgcctccatc acccgccagc tgcacggcta ctacgacgcc ttcggcctgc ccgcgagcgc
    25621 gctgaagccg gtgacgctcg acgctgccgg tcacaccatg cccaccaccg cctacggccg
    25681 cgcctgcggc gtgaccgacg agccctacat cggcaagtgc ggcttcgagg ccgcgcatgc
    25741 gatcctcgac tggatctacg gcccggccgt cgccccgccg cgcaccacgc ccactccggc
    25801 cggccgcttc gccgagttcg accagcgcgg ctacatcccc gagaccggca tcttcagcta
    25861 cctgtggggc accggcctcg acaagaccgg ctgggtgtac attccgcccg cctgcgccgc
    25921 cggcgagcgc tgccggctgc acgtggtgtt ccacggctgc aagcaggggc agagcttcct
    25981 gccgctgcgc cgcccgcccg gcggagggct gtacaacggc accaccttcg tgcgcaacac
    26041 cggctacgac cgctgggccg acaccaaccg cctggtggtg ctgttcccgc aggcggtgtc
    26101 gattccgtgg aagaatccca acggctgctg ggactggtgg ggcttcaccg acgccgacta
    26161 tgccacccgc gacggcatcc agatccgcag cgtgcgcgcg atgatcgagc ggctcgcctc
    26221 cggccggcgc gactgaagac cgcggccgcg gcgccgctgg cccgccccgc gctggtggac
    26281 tataaggaaa gcggagttcg cctgcccgcg gccccctcag ggcgggtgga gcgcagcgac
    26341 tcgtccgccc aagcgaggaa gttttcatgt cctacgtcgg agagcccttc cgccacgacc
    26401 tgttcgtgag ctacagccac ggcgacgacg gcagcggtgg tgcctatctc aagccatggt
    26461 cggccgcctt cacgcacgag ctcgagcgcg agctgcgcgc cgatcggcgc ttccgcacca
    26521 gcctgagcgt gttccgcgac caggaccacc gcccggagca gagcctcgat ccgatggcgc
    26581 cgctcaccgc ccagctgcag gagcagatcg ccggcgctgc gctgctggtg gtgttgatgt
    26641 cgcccgacta cctcgcctcg aagtggtgcg cggacgagcg cgactggtgg ctggagcgtc
    26701 aggttgcgct cggcctgccg cacgaggagc gcatcgcggt ggtgcgcatc tggcccaccg
    26761 acacgccttg gccggccgcc ctgtgcgacg cgcgcggcga gccgctggtc ggcttcggct
    26821 tctacccgcc cgccggcgtg ccgccgcggc cgctgggctg gaccgacctg cccggcgcct
    26881 tcggcagcga gttccgcagg gccctgctcg acatggtcgg ccggctctac cccaagctcg
    26941 agacgatgcg cgcgcgtgcc gaggagttgc gccgccagcg cgaggaggcc gagcgcctgg
    27001 tccgcgacgg cggccagacg ctctacctgc acggccgcag cgaccatgcc gaggcctggg
    27061 aggctgcggc gctcaagctg gtcgacaagg gcttcgcggt ggtgccgggc gaacccgacc
    27121 gggtcgaaag cgatccggca cgcctgcagg aggtgcgcga gcgccgggtc gagaccctga
    27181 gcggctgcga cgccctgctg ctgctcggca ccgacgacgg gcgcgccctc gacgccgacc
    27241 tcgtggtggt gggcaagcac gaccgccagt cggcgcgcgc acgctcgcac cgactgctgc
    27301 cctgcggcct gctcgacacc gccggcgccg ccatcgccac cagcgtgcgc cgcgccaccg
    27361 cgcgcatcgt gcaggcggac tggatcgatg gcaccgatga agactggccg gtcgcggtgc
    27421 gcgactggct gggcggcaag ggcgtgcagg ccgggggggc gccatgaagc cggacgcgtc
    27481 cgcacccgca accgccgaag acaccttcga cgcggtcttt gcgatccgcc tgccgccccg
    27541 gccctatccc ggcctgcgcc ccttcgagca gcacgaatgg ccgatcttct tcgggcgcga
    27601 gcgcatgacc gacgagatcg tcgagcgcct gctcggcctc cggctgctcg tggtgcatgg
    27661 cgactcgggc tgcggcaaga gttcgctggt gcgcgccggc gtgctgccgc ggctggagca
    27721 ggagagtgcg cgcggcggcg tgcgctggcg cacctgcacg gcattgccgc gcgcggcgcc
    27781 gctgtggaac ctcgcacacg cgctcgccgc gctcgacacg cccggcgagg gcgacgccga
    27841 cgcactcgag gcgcgcacca tcgccttccg gcgcgcgctc aacttcggcc gcgaggcccc
    27901 cgcggcgctc gccgagctgc tcggctgcgg gccgcgcaac caggtctgca tcctggtcga
    27961 ccagttcgag gagctcttcg agcacgcccg ccgccatggc cccgaagaag ccgcgctgct
    28021 ggccgcctgc ctggtgggac tgctcgacgc gccgccgccc gggctgtatg cggtgctgac
    28081 catgcgctcg gagttcctcg gcgcttgctc gcgctacgag ggcttcgccg cggcggtcaa
    28141 ccgtgcgcaa tacctgctcc cgcgcatgga gcacgacgac ctgatgcgcg cgatccgcga
    28201 gcccgcggtg ctctacgatg gcgaggtgac gcgcgagctg gccgagcgcc tgatcgtcga
    28261 tggcggcggg ggacaggacc agctgccgct gatccagcac gggctgatgc tgctccatga
    28321 cgagcatgcg cgcacatcgg gtcaagccct cgcgggaccg accccgggcg ctccggcatg
    28381 gcggctcggg atggaacatt accgcgccga ggacggtctc gccggcctgc tctcggcaca
    28441 tgccgacgcc gtgctggcgc gcgccgggca gcggtgcttc ggcggcgagg ccacgcgggt
    28501 ggtggaagac ctcttccgcg cactcaccga catcaacgcc gagggccagg ccatccgcag
    28561 gccgtgcacg ctcgagcgcc tggtggcggt gaccggcacc aacgagcctg cgctgcgctg
    28621 cgtggtcgac gccttccgcg ccgacggcgt gtccttcctc aagccctacg ggcacgaggc
    28681 attgcgcgcg gaagagctca tcgacatcag ccacgaggcc ctgatccgct gctggcgacg
    28741 catcgccgag ccgcgcgagg gctggctggc gcgcgaattc cgcaacggcc tggtgtggcg
    28801 tgcgctgctc gtgcaggcgg acagcttcga ccgcgacccg ggcaacgtgc tcggcgccac
    28861 caccaccgac gagcgcgaac gctggctgcg ccggcgcaac gccatctggg cggagcgcta
    28921 cggtggcggc tgggagcgcg tgcagcgcct gatcgcggcc agcgtcgaag cgcgcgccct
    28981 gcgcgccgcc gaacgcgagg ccgccgagac gcagcgccag gaggcgcgtc gcctgcgtcg
    29041 gcgcagccgg gcgctcgcga tcgggatcgg cgtgctcgcc ttcaccagcg cgctcggcgg
    29101 gctggcctgg cagcagtcgc gcatcgccga ggacgcgcgc cgggtcgccg aaggcgagcg
    29161 cgagctcgcg ctcaccgcgc gcgacgaggt cgtgcgccag ctcgaggccc tggtcgaggc
    29221 gcgcgaggcg gaggccgccg cacgcgccgc ggccgaggcg gtggcgcagg aggcgcggca
    29281 gtcggcgagc gcgctcgccg gcgtggtcga cgagctcgaa cgcgccagct ctgcggccaa
    29341 cgcaccggcg agcggcgacg gccaggcggt gcagcgcagc ctcagcgagg ccaagtccga
    29401 gctgcgcgcg caggtgagca acctctccaa gctctcggtg cagcaggccg cgccgccgct
    29461 cgccgcggca ccggctccgg cgccccccgg ggcgctcgca ccgcggatgt ggatctacat
    29521 cgccgaggag agccagcgcc cggcggccga ggcgctggaa gcgcagctgc gcagcgtgcg
    29581 catcggcgac gccgcgctcg agctgcccgg catcgtcctc gtcaaggccg cgcccacgcg
    29641 cagcatgctg cgctgcttcc gcaccgagga atgccgccag gacggcgacg cgctggtgcg
    29701 cgcgctcggc gggttgctgc agtctcccaa gccgagcctg gaggatttca gcgcgctcta
    29761 tggcagcagc ggctcgatcc gcgcgcgtca ctacgagctc tggttcgccc ccggcgcgat
    29821 cgtgctgccg gcgcgcaagg gaccttgagc atccgcaaag gaaaaggccg gcgaaccggg
    29881 ttgccccggt tcgccggcct cgacggcgcg agccgatcct cagtcgcgcg ggatcagctg
    29941 cgcgcgccct tcaggatggc gttgagcgtg gcgctcggac gcatcaccgc cttgcacttc
    30001 tcggcgtcgg ccttgtagta gccaccgatg tccaccgcct tgccctgcac ctcggacagc
    30061 tcggcgatga tcttctgctc gttctcggcc agggccttgg cgagcggcgc gaacttcgcc
    30121 gccagctcgg catcctcggt ctgcccggcc aggcgctccg cccagaactt ggcgaggtag
    30181 aactggctgc cgcggttgtc gagctggccg gtcttgggcg agggcgactt gttctcgtcg
    30241 agcaggcgcc cggtggcctc gtccagggtc ttggcgagca gcttggcctt gccgttgccg
    30301 gtcttgatgc ccagatcctc gagcgatacc gccagggcga ggaactcacc gagcgaatcc
    30361 cagcgcaggt ggttttcctg caccagctgc tgcacgtgct tgggcgcgga gccacccgca
    30421 ccggtctcgt acatgccgcc accgttcatc agcggcacga tcgacagcat cttggccgag
    30481 gtgcccagct ccatgatcgg gaacaggtcg gtgaggtaat cgcgcaggat gttgccggtc
    30541 accgagatgg tgtcgaggcc gcgcgcaacg cgctcgagcg tgtaacgcat cgcacgcacc
    30601 tgcgacatga tctggatgtc gaggccgctg gtgtcgtgat ccttgaggta ggtcttgacc
    30661 ttcttgatca gctcgttctc gtgcggacga taggggtcga gccagaagat cgccggcatg
    30721 cccgagttgc gcgcgcgcgt gacggcgagc ttgacccagt cgcggatcgg cgcgtccttg
    30781 acctggcaca tgcgccagat gtccccctct tcgacgttct gcgacagcag cacctcgccg
    30841 gtgtcgagat cggtgatgtt ggccacgccg gcttcgacga tctcgaaggt gcgatcgtgc
    30901 gagccgtact cctcggcctt ctgcgccatc aggccgacgt tcggcaccgt gcccatcgtg
    30961 cgcgggtcga agttgccgtg ccatttgcag aagttgatca tctcctggta gatgcgggcg
    31021 aaggtcgact ccggcatcac gcacttgctg tcgtactgct tgccgtcggc accccacatc
    31081 ttgccgccct ggcggatcat cgccggcatc gaggcatcga cgatgatgtc gttgggcgag
    31141 tggaagttgg tgatgccctt ggccgaatcg accatggcca gcgccggacg gtgctcctgg
    31201 caggcgtgca ggtcgcggat gatctcgtcg cgcttggact cgggcagggt cttgatcttg
    31261 tcgtacaggt cgaccatgcc gttgttgacg ttgatgccga gctcgtcgaa cagcttgccg
    31321 tgcttctcga aggcgtcctt gtagtagatc ttgacgcagt ggccgaagac gatcgggtgc
    31381 gagaccttca tcatcgtcgc cttcacgtgc agcgagaaca ggatgccggc ctcgcggcag
    31441 tcgtcgagct cgcgctcgta gaactcgcac aacgccttct tgctcatgaa catcgagtcg
    31501 atgatctcgc cttcgagcag gtcggtcttc ggcttgagca ccacggtctt gcccgacttg
    31561 gtgatcagct ccatcttgac cgagcgcgcg cggtcgagcg tcatcgactt ctcgccgtgg
    31621 tagaagtcgc cgtggtgcat gtgcgagacg tgggtctgcg accactgctt ccactcaccc
    31681 atggagtgcg ggttcttctt ggcgaagttc ttcactgcgg cgggcgcgcg tcggtcggag
    31741 ttgccctcgc gcagcaccgg gttgaccgcg gaaccgaggc acttgccgaa gcgggcgcgg
    31801 agcgcctttt cctcgtcggt cttggggtcc tcggggtagt cggggatctt gtagcccttg
    31861 tcctgcagct ccttgacgca ggccttgagc tgggcgaccg aggcgctgat gttgggcagc
    31921 ttgatgatgt tggtgtcggg ctcgagggtc aggcggccga gctcggcgag cgtgtcgggg
    31981 acgcgctggt cttcgctcag gtactcgggg aactcggcga gcacgcgcgc cgacaccgag
    32041 atgtcggcct tctcgacctc gacgcctgca gggccggtga aggtgcggat gatcgggagg
    32101 aaggcgcacg tcgccagcag cggcgcttcg tccgtgagcg tgtagatgat cttggatttg
    32161 cctgcagaca ttgatttccc ctatatgttt tagatcttgt cccgactacc cgatggcgac
    32221 cctctgtcgc cggcgcggca cagccgccgc acgatcgcag tcgcccggaa aaataccact
    32281 tatcgacctg tcgggcatcg aaaccttctt tcacatcgcg aaataaactg cgccaagccc
    32341 cgccaggcct ggaatccggc accgctgcgg gggtctgcgc cgcaggctcg acagcgcggg
    32401 cgatctgtcc gatgctgccg ccctcgctcc tctccttccg cccactgctt acgcccactc
    32461 cttccaccct ctccacgccc ctgcgctgcg cccgagcgcg cccccacgat catgaacctc
    32521 ccttcttcac cgcctgcatg cggcgacccg cggccggcct cgcgcagccc ggcccgcacg
    32581 ctcgtgttcc gcggccacca gctgctggtg gaccgtgcgg gtgcgcccag cgccggcccg
    32641 agcgcctggc gggccggcct cgccgcgctg cgcacgctcg acttccccat gcccagtggc
    32701 ggggcctgga cggtggtcga ggtcgagcgc acgatcgagg cgcccgacgg acatgccttc
    32761 cagcacctca agtcgctgct cgacacgctg gccgaagacc gcctcgcgct cgccgcacgc
    32821 gccctggagc tgctcgagtt cgaccacgcg caccgcttct gcggcgcctg cggcgcgccc
    32881 accacgccga ggacggaccc gccggcgcgg cgctgcagcg cgccggactg cggccgcgag
    32941 cacttcccgc gcgtgtcgcc ggtggtgatc gtggcggtgg agcgcggcgc cgagatcctg
    33001 ctcgggcgct cgccgcactt tccgcccggc ctctacagca cgctcgccgg tttcgtggac
    33061 gcgggcgagt cggccgagca ggcggtgcac cgcgagatct tcgaggagac cgggctgcgc
    33121 atccgcgccc cgcgctactt ctccagccag gcctggccct tcccgcatgc gctgatgctc
    33181 ggctaccagg ccgagtacgc cggcggcgac atcgtgtgcg ccccaggcga gatcgaggac
    33241 gcgcgcttct tccatgtcga cgcgctgccg ccgctgttcc cgatccgcta cgcgatggcc
    33301 aaccagctgc tgcgcgactt ctgcctgcgc cacgggcgcc cgtggccgcc cgctcaggcc
    33361 gccccgacgg ccgcctgagc gtcacgccgg tcgacgatct tcagcgccac cagcaacacc
    33421 gtgccgaccg ccatcatcgc cgcggcgaac cacagcccgc cggcgtagct gccgaaggtc
    33481 tcgcccagcc agccggtcac cgccgggccg aggatctgcg ccacgccgta ggagacggtc
    33541 atcttgccca tcatcttggc cggtcgcgtc gggtagtagc gccccgccat ggtcagcacc
    33601 aggctcacca tgccgacgaa ggtgccaccg aagagcagcg cgccggcgat cgccccgagg
    33661 ctgccaccga ccaccaccgg cagcaggatg ccgacgatct gcagcaccgc ggcgaggatc
    33721 agcgcattca gcgcgccggt gcggcgggcg atgaagtccc acacgatgca ggccggcatc
    33781 gccgccaggc cgatggcgag gaagctccag ctgccctggc cctccagccc gggcaggcgg
    33841 ttgacgatgg cgacgatgaa ggtcgcgctg accacgaagc cgacgccggc gcagaagtac
    33901 gaggccatga acacccgcat gaacagcggg ctgggcgggt tgtcgtgcat cggcgcgccg
    33961 ctcttggtca ccgggctggt atcgggcgcc ggcagccagg ccagcgcggg caccagcagc
    34021 acgcaggcga gcgcggtgaa cacgtaccac tgcgcgcgcc agtcgagcca caggctcatc
    34081 accgccaccg ccaccgagca gccggcgatg cccaggccga tgccggcgaa gtggatgccg
    34141 agctcgtggc ggtggccgtg gcggatcagc cagttgagga tcagcccggt gccgagcagc
    34201 atcgcggccg cgctcgacag cccggcgagg tagcgcgaca ccgcccacac ggtgaagtcg
    34261 gtggtgaggc ccatcatcag cgtggtgagc accgccacca ccatgccgat gcggtacagg
    34321 cggtccttga gcaccaggtc gctgatcgag gccgcaagca gcgccccgct caggtagccc
    34381 aggtaattga tcgccgccag ccagccaccc tcggccagcc ccagtccggc ctgggactgc
    34441 atcaggggca gcagcggggt gtaggcgaag cgcgccacgc cgagcgcgag catcaggctg
    34501 aagatgcccg cgccgagcac cttcatgcgc tgtttctgat ccgacatcgt tttatttnnn
    34561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    34621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnntcc ggcctgcgtt accatcgcgc
    34681 cgctccccct ccggttgtcg tcccatgtcc ctgctgcgcc tgctcttcct gctgctgctc
    34741 cccctcctct ccatgcacgc cgctgccgag gcgccaccgc ggccgcagcc cgacgagctg
    34801 cgtgcacgcc tgcaggcgct ggccgaacgc aagctgcccg aggccgagca gcgcaccgcg
    34861 cagcaggcgc tggaacaggc ccaggccagc ctcgccagcg ccgaggacta tcgccgccgg
    34921 ctcgatgcgc tcaagcagac cctcgccgac gcccctgcgc agatcgccga ggcacgccgc
    34981 cagctcgccg cgctgtccac cgccgcgcca gtcgcggagc cggcggccga caccccgctc
    35041 gcacgcctgg aggaacgcct cgccgaacag gaggccgcgc tcgccgactg gcgccgccgc
    35101 ctcgacgagg ccgacggact ggtcgtcggc tctcgcaccg gccccgagcg cgcacaaacc
    35161 gagatcagca ccggccaggt gcgcatggcg gagatcgaga ccacactcgc gagcggacgc
    35221 gaagccgggc gcgacggtcg gcccctgggc ccggagcgtc gcgacgcgct cgccgccgag
    35281 tggcatgcgc tcgacgctca gctcacgctg cgccgccagg agctcgcagg caacagcggc
    35341 ctgatcgacc tcggtctggc ccgccaggag ctcgcacgcc tgcaggtcgc ccgcctggag
    35401 gacgcagcgc acgtcctcca ggacgcgatc agccgccagc gcgccagcca ggccgagcag
    35461 accgtgcagg cgctcgccga cgtgcgcgcg gacacgagcg gcgacgccct gctcgcgcgt
    35521 gaggccgcga ccaacgaaga gctgtcccag tacctgctgc gcgccaccgc gcatctcgac
    35581 accctgaccc gacgcaacca gaaggtcagc cagcagctcg acgcgatcaa tcgcagcacc
    35641 gcggtgatcg acgagcagat cggcgtgctg cagggcagcg tcctgctgtc gcgcatcctg
    35701 ctcgagcagc gccgggcgct gcccgcaccg gtggccgatg ccggcctcgc cgaccagatc
    35761 gccgacatcc gcctctatca gttcgagatc aacaagcagc gcgagcagct caccaacccg
    35821 gccgcccatg ccgagcgcct gctcgccggg gccccggcgg gcgaggccga tccgacgctg
    35881 cgcgagccgc tcctcgccct gctcgccacc cgcggcgagc tactcgagcg cctcaaccgc
    35941 gagctcaacg cggtgctcgc ccagtcgatc accctgcagc tcgccgagcg ccagctgctg
    36001 gtcagcgccg accgcctgcg cgccacgctc gacaagcaga tgttctggat cccgagcaac
    36061 cgcccgctcg acctcacctg gctgcaggcg gtgccgggcg cgctcgccaa gcagttcggc
    36121 gcgattccct ggggctcggc catcggcgag ctgtgggccg gcctgcaggc gcggcccttc
    36181 ctgttcctgc cggtgctgct ggtgagcctc gggctgttcg cgcgccggcg ctggctgcgc
    36241 gaaaagctcg acagcctgca cgccgacatc ggctacgtgc gccgcgacag ccagcgccac
    36301 accccgctgg cgatcctgct caacctgctg ctcaccctgc cggtgagcct gctgctcgcg
    36361 ctcggcggca tcgcgctgca gatggacgcg cgcggccaga atgcggccct gggcgcagcg
    36421 ctgatgcaga tggcgcaggc ctggctggtg ttccacaccg cacaccgcct gctcaccccc
    36481 ggcggggtcg ccgagcgcca cttccagtgg cccgtcgagc gcgtgcgcgc gatgcaccgc
    36541 aacctgcgca agctcggcct ggtggtggtg gcggtggtcg cggtggtcgc ggtcgccgag
    36601 cgccagcccg agagcctcgg cagcgacgtg ctgggcatgc tgatcctgct cgtcggctac
    36661 gcgaccatgg cctggctgct ggggcgcggc ctgctgcaca cccgcctcga cgaccgactc
    36721 tcgccgctgc gcgtgttcgt ggggctggcg ctcgggctga tgccgctggc actcatcggc
    36781 gcgctggtga tgggctacta ctacaccgcg ctcaagctca ccgggcgcct ggtcgacacc
    36841 ctctacgtgc tcatcctgtg gcggctggcc gaaggcgtgc tggtgcgcgc gctcggcgtc
    36901 gccgcgcacc gcatcgacca ccagcgcgcg gtcgcgcgcc gcgaggccgc cgagcgcgag
    36961 ggccgcgccg gcgccgacag cgagcccgcg gcggtcgccg aagcgccgat gctcgacatc
    37021 gcgcgcatca accagcagtc gctgcgcctg ctccaactca ccctgctgtc cgggctcgcg
    37081 gtggcgctgt actgggtgtg ggccgacctg ctctcggtgg tctcctacct cgacaacatc
    37141 acgctgtacg agtacgcgag cggcagcggc gaggccgccg gcgtggtgcc gatcagcctc
    37201 gccgacctgc tcggcgcgct ggtgatcgcg gcgatcgcct tcatgctcgc caccaacctg
    37261 cccggcctgc tcgaggtgct ggtgctgtcg cggctcaagc tcgcccaggg cagcgcctac
    37321 gcgatcacca cgctgctgtc ctacgtgatc gtcggcgtcg gcatcgcctc cacgctcggc
    37381 acgctggggg tgagctggga caagctgcag tggctggtgg cggcgctgtc ggtgggcctg
    37441 ggcttcggcc tgcaggagat cttcgccaac ttcgtgtccg gcctcatcat cctgttcgag
    37501 cgcccgctgc gcatcggcga cacggtgacg atcggcaacg tctcgggcac ggtgagccgc
    37561 atccagatcc gcgccaccac catcaccgac ttcgaccgca aggagatgat cgtgcccaac
    37621 aaggccttca tcaccggcca gctcaccaac tggtcgctga ccgacaccgt gacgcgggtg
    37681 acgatcaagc ttggcgtggc ctacggcgcc gacctcgagg ccacccgccg cctgctgctc
    37741 cggatcgccg ccgacaaccc gcgcgtgctg agggatccgg agccgctggt gttcttcctc
    37801 aacttcgggg ccagcacgct cgaccacgag ctgcgggtgc acgtgcgcga actcgccgac
    37861 cgcaacgccg cgatcgacga gatcaaccgc gagatcgacc gccgcttccg cgagcaaggc
    37921 atcgagatcg ccttcaacca gatggatgtc cacatccgca gcatcgcgga cggccgcgag
    37981 gccttgctgc agagcacacc ggccgttccg cccgcgccct cgtcggggct gcagggctga
    38041 atcgaggcac ggcgcggaac gggcgaccca cgcccccgcg ccagccgcgg caccgccggg
    38101 gaccttgccc gggccggtcc gctagcctct ggagcgcctg cgcaggccgc ccaggcgctc
    38161 gagcagcacg cgcagacgca tcatcgggcc cggcgctcga ggcgcaaagc ggcgcgcctc
    38221 ggcgcgcgcc cacgactcgg cctgcgcacg ggcgcaacat tcaccggcgc tggcgtcgga
    38281 catcgccgcc gctgcgcggg cgtcgggggt cacgacggcc tgcggccatc ctggccgtcc
    38341 ctgcgcacct cgtcctcgac ctccacctcg cggatcacct cgccctcgat gatcagcccg
    38401 cggttgccgc cggccgggcc gtagccgccc gcccgcccgc cgcctgcgga cgcctgcgcg
    38461 tccatctgcg cacgcatcgc cttgcgcagc gcgcgcgtct tccaccacac ccagccccag
    38521 atcgccacgc cggcggtcag cagcaccgcg aagaaggcga ccgagaaggt cagcgcgagc
    38581 atgaacacgc ccgccatcac gaccgcgccg accaccttct gcagcagcgt gggcggcttg
    38641 gcggccggtc cgccgagggt ctggaagagg ccggagaatc ggggatccct gtacatgagt
    38701 cggtcctgtc gggcggcgcg gaccatccgc gccgcatgcg gaagtgtgag cccccgccgg
    38761 aaaaaagatt ccacgcgagc cggggtgcgc atggattgct tacacattct cgcccaagcg
    38821 ggccgccctt gccgagttca ccggccgccc cccctgtagg agcggcggca gccgcgaagg
    38881 aggcggtgcg gcggcgatg
//
LOCUS       DAOTIN010000021        38878 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_1115_length_38878_cov_8.410993, whole genome shotgun sequence.
ACCESSION   DAOTIN010000021 DAOTIN010000000
VERSION     DAOTIN010000021.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 38878)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 38878)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38878
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1115_length_38878_cov_8.410993"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1136)
                     /gene="ppx"
                     /locus_tag="P5537_05185"
     CDS             complement(<1..1136)
                     /gene="ppx"
                     /locus_tag="P5537_05185"
                     /EC_number="3.6.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004309 - exopolyphosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006798 - polyphosphate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exopolyphosphatase"
                     /protein_id="HRV77473.1"
                     /translation="MQDLIAAIDLGSNSFRLQVGRIVNDQIYPLDGLKEAVRLAAGLS
                     PDKMLDLASQQRGVAALQRFHERLRDFPPTRVRAVATNTLRVAKNAPEFLIRAEAALG
                     FPIEIIAGREEARLIYVGVAHTLPDPHRQQLVVDIGGGSTEFIVGKSFESQLLESRYM
                     GCVGYSLRYFPDGRIDKRAFKEAELAARRELQTISAAYREAGWEEAVGSSGTAKAIVE
                     ILEQNGLSKGGITREGLEKLKALLLRAGSLDNIDLAGLKGDRLPVILGGFAIMSAIFK
                     EFELEHMVFSEGALRLGVLYDLLGRYHHHDLRDATVSAFVRRYGVDLRQAQQVADTAC
                     HLLAQLEPETADPEHDDHRFLRWAAMLHEIGISVAHSSYHKHSA"
     gene            1318..3399
                     /gene="ppk1"
                     /locus_tag="P5537_05190"
     CDS             1318..3399
                     /gene="ppk1"
                     /locus_tag="P5537_05190"
                     /EC_number="2.7.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009358 - polyphosphate kinase complex
                     [Evidence IEA];
                     GO_function: GO:0008976 - polyphosphate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006799 - polyphosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate kinase 1"
                     /protein_id="HRV77474.1"
                     /translation="MHADRMPLNYSSEHFLNRELSLLQFQRRVLAQAADPTVPLLERL
                     RFLCIVSSNLDEFFEIRVSGIKEQLRIGSRKSGEDGIAPAELLERVSDEVHEIISEQY
                     QLLNGDILPALEKEGVVFPRRSLWTEAQRAWIHDYFMREVMPVLTPIGLDPAHPFPRV
                     LNKSLNFAVELEGRDAFGRDSGAAIVQAPRALPRVIRLPRELCEQEYGFVFLSSVLHA
                     HVGELFSGMNVLGCYQFRVTRNSDLFVDEEEVKDLRTSLKGELQQRHFGDAVRLEVAD
                     NCSEEMAGFLLQHFHLTPDDLYRTPGIVNLVRLMQVPDWVERPDLKYSPFVPGLPKVL
                     DKRRQVFTAIRGGDILLHHPFQSFAPVIEMLRAAADDPQVLAIKMTVYRTGTDSVLME
                     HLARAAQKGKEVTVVLELMARFDEEANITLANRLEEVGAHVVYGVFGYKTHAKLLMIV
                     RREEDGLRRYVHMGTGNYHPRTTRFYTDFGLLTCNQEIGEDVAAVFKQLTGLGKATEL
                     RHLWQAPFTLQPNVVAAIRREAEIAREGRRGRVIAKMNALLEPETIEALYEASQAGVE
                     VDLIVRGPCALRPGVPGLSDNIRVRSVVGRFLEHHRIFHFHADGAEHMYLSSADWMDR
                     NFFRRIEIAFPVLDPRLKRRVMKEGLRPYLGDNCQAWDMQPDGKYRRKHPRSIRRAAQ
                     LILLKELAASS"
     assembly_gap    3579..3678
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<3679..5843)
                     /locus_tag="P5537_05195"
     CDS             complement(<3679..5843)
                     /locus_tag="P5537_05195"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HRV77475.1"
                     /translation="MVSVTHAISQGDTAPPIDLLAAGLEVGERGRIEAALEWIADLYE
                     GKVLGTGEPTWTHAIGAALIAASLRLDAETRMAALLFAAWEELDDPAEEIEARFGPAI
                     TALVRGLHKLNGLRVLTRLTTNASAPEIRAQTEVLRKMLLAMVEDIRVVLVRLASRTQ
                     TLRFYTDLPGEARVEVARESLDIYAPLANRLGVWQIKWELEDLSFRFIEPETYKRIAR
                     MLDERRVEREQFIHDSIERLRSELAAVGIEGEITGRAKHIYSIYNKMRKKRLDFSQVF
                     DIRALRVLVPEIKDCYTVLGIVHQMWQPIAKEFDDYITKPKGNNYQSLHTAVLAGDGR
                     ALEVQIRTFDMHKHAELGVAAHWRYKEGARQGGDYDEKIALLRNLLSWRDEVTDAAHW
                     VEQLKRASLDDTLYVLTPQGRVVDLPRGATPIDFAYRLHTDVGHHCRGAKVDGHLVPL
                     NTPLESGQTVEIVTAKEGGPSRDWLDVRQGYVATSRARSKIKQYFAQLDEEEILSRGR
                     NFVTKEMQRDGHGQANIDGLADRLGFKNAEALYLAAGRGEVGPRAMQTALREGNAPEP
                     AAEAEPEFVVSRSRSRSGDNQDKILIDGVGKLMTSLSRCCKPAPPDAIEGFVTRGRGI
                     SIHRVDCADFQDLARKHPERVIPAEWGEKAHDTRNALYQVDINVQASDRQGLLRDISE
                     VLSREKLNVIAVNTLTKKGTAYMRFTMEVGGIKQVQRAIT"
     gene            5987..6760
                     /locus_tag="P5537_05200"
     CDS             5987..6760
                     /locus_tag="P5537_05200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent peptidase"
                     /protein_id="HRV77476.1"
                     /translation="MLQILRRLLGIAPARPTVDAAQWARVEARLPFLDHLDPTDRAHL
                     REMALAFLASKQFHGAQGLELDDDMLLAIALQACLPVLHIGLQAYDGWVGVIVYPGDF
                     LIPRRIVDEAGVLHEYEDEVLGEAWEGGPVLLSWFAGEDGPAGINVVIHEFAHKLDME
                     NGGVDGLPRLRPGMSRHVWAEAFGKAYEDFCAEVDRGGETAIDPYGTEHPGEFFAVVS
                     EVFFEAPLTLRDRFPAVYDQLAQFYGMDPAARAAPTSGG"
     gene            6762..7226
                     /locus_tag="P5537_05205"
     CDS             6762..7226
                     /locus_tag="P5537_05205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HRV77477.1"
                     /translation="MSTPKRLLIVHHTQSGNTGRLAAAVHEGAQRVAETETRLLRAFD
                     AGTADLLACDGLLLGTPENFGYMSGALKDFFDRTYYPCEGKLVGLPYAVFVSAGNDGT
                     GAVREIGRIANGYGWKTVAEALIVRREITPADLERARELGEAMAAGLAMGVF"
     gene            7442..7882
                     /locus_tag="P5537_05210"
     CDS             7442..7882
                     /locus_tag="P5537_05210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host attachment protein"
                     /protein_id="HRV77478.1"
                     /translation="MAITWILVANASLAKLYANLGPNKGLTLVKELIHPESRQKNGDL
                     VSDRAGANGSNGTGGGSMQPQTLPKQHEAKVFAQELAQTLYQGRTSNAFKRAILVAPP
                     AFMGLLNAVLDGPTAQMVTDRFEKDYTKTPQDELGQHLGSTIFL"
     gene            complement(8154..9602)
                     /locus_tag="P5537_05215"
     CDS             complement(8154..9602)
                     /locus_tag="P5537_05215"
                     /EC_number="2.7.7.13"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate
                     guanylyltransferase/mannose-6-phosphate isomerase"
                     /protein_id="HRV77479.1"
                     /translation="MTIKSVILSGGSGTRLWPASRESYPKQLLPLTSERSLLQETALR
                     LKDFPGGEVDPRPLVVTNEEYRFIIAEQLRQIGVRSPQIVLEPVGRNTAPALTLAALV
                     AADEGDPILLVMPADHVITEQPAFQHAIAVGAKAAAKGALVTFGIVPDRAETGYGYLR
                     SGVTLAEGEGARALLEFVEKPDRATAEAYVASGAYYWNSGIFMMKASVWLAAIRRFAP
                     EMAAACTAAVGGCTHDADFIRLDTAAFERSPSDSIDYAVMEKLAEAPELGQGVVVPLS
                     AGWSDVGAWDALWAVSAKDGEGNAARGEVLFEACRNTLVHAGSRLVAAVGCEDMVVVE
                     TPDAVMVAHKDRTQDVKKVVARLKAEGRTLTQSHRKVYRPWGWYDSIDAGERFQVKRI
                     VVNPGAKLSLQMHHHRAEHWIVVKGTAEVTNGERSFLLAENESTYIPLGHTHRLSNPG
                     KVPLEIIEVQSGSYLGEDDIVRFEDTYGRGTS"
     gene            complement(9640..10530)
                     /gene="rfbD"
                     /locus_tag="P5537_05220"
     CDS             complement(9640..10530)
                     /gene="rfbD"
                     /locus_tag="P5537_05220"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HRV77480.1"
                     /translation="MKILLLGKNGQVGWELQRALAPLGIVVALDRGGADGLRGDLEDL
                     DGLDRTVRRIVPDVIVNAAAYTAVDKAETDVERAQRVNAEAPGVLAVAAAAVGALLVH
                     YSTDYVFDGSGDTPWREDAATAPLSVYGRTKLAGEEAIRAAGCRHLILRTSWVYAARG
                     GNFARTMLRLGAERERLTVIADQHGAPTGAELIADVSAHAIRAERANHGLGGTYHLAA
                     SGETSWHGYASFVIEQARELGATLKVSEIAPIGTRDYPTAAVRPLNSRLDSARLRERF
                     ELALPDWRDGVARMLREILD"
     gene            complement(10527..11597)
                     /gene="rfbB"
                     /locus_tag="P5537_05225"
     CDS             complement(10527..11597)
                     /gene="rfbB"
                     /locus_tag="P5537_05225"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004372227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HRV77481.1"
                     /translation="MILVTGGAGFIGANFVLDWLAASDEPVINLDALTYAGNRETLAP
                     LEGDARHLFVHGDICDRALVERLFAEHKPRAVVHFAAESHVDRSIHGPGAFVRTNVDG
                     TFTLLEAARMHWSALPAGEREAFRFLHVSTDEVYGSLGPNDPAFTETKAYEPNSPYSA
                     SKAASDHLVRAWHHTYGLPVLTTNCSNNYGPYQFPEKLIPLMIVNALAGKPLPIYGDG
                     QNVRDWLYVGDHCGAIREVLARGRLGETYNVGGWNEMANIDIVHALCALLDELRPDAD
                     GSYARLITYVKDRPGHDRRYAIDAHKIERELGWRPAETFQTGIRKTVQWYLDNPGWIA
                     NVQSGAYRDWVARNYAGREVQG"
     gene            11884..14271
                     /locus_tag="P5537_05230"
     CDS             11884..14271
                     /locus_tag="P5537_05230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HRV77482.1"
                     /translation="MLPPIEHRIAEELGVSPRQVIAAVQLIDDGATVPFIARYRKEVT
                     GGLDDTQLRTLEERLGYLRELEDRRATVLASIEEQGKLSPELRAEVEDADTKQRLEDL
                     YLPYKPKRRTKAQIAREAGIGPLAEALLADPALTPEVEAERYLNAELGFADTKAVLDG
                     ARQILMEHFAEDAALLGELRGYLHEHGLVRSRVIDGKENEGAKFRDWFDFAEPIATMP
                     SHRALALLRGRNEGVLRLALDVDRPDPDAPHPCEGRIAVRFGIRNQGRPADRWLAETA
                     RWAWSVKISIHLELELMSELRERAEEEAIRVFARNLKDLLLAAPAGTRATIGLDPGIR
                     TGVKVAVVDATGKLVDTATVYPFEPRRDRESSIATIAALAQKHAVELIAIGNGTASRE
                     TDALVAELMKRHPELPLTKIVVSEAGASVYSASELAAREFPELDVSLRGAVSIARRLQ
                     DPLAELVKIDPKSIGVGQYQHDVNQGRLAKSLDAVVEDCVNAVGVDVNTASAPLLARI
                     SGLNATLAGNIVEYRNTQGPFRSRSALKEVPRLGPKTFEQAAGFLRIPSGDNPLDASS
                     VHPEAYPVVERILAKVQKGVRELMGNGSFLKSLKPAEFTDERFGLPTVQDILAELEKP
                     GRDPRPEFRTATFREGVETLKDLEPGMLLEGVVTNVTNFGAFVDIGVHQDGLVHISAL
                     SNTFVKDPHSVVKAGQVVKVKVLEVDLPRHRIALTMRLGDEVAAKRGGAGAGRDEGAP
                     RRGEGGPAPRGEQRPRGSDPRRSPAQGKGGARQEPSRPAAGNALAEAFARARGNK"
     gene            14282..14635
                     /locus_tag="P5537_05235"
     CDS             14282..14635
                     /locus_tag="P5537_05235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004318245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsC family reductase"
                     /protein_id="HRV77483.1"
                     /translation="MPTTIHGIKNCDTMKKTFAWFEGAGVAYRFHDYKKAGIDAATLA
                     RWCERLGWEALVNKRGTTWRKLAPEQQAIADTAAAVALMQAQPSLIRRPVVEFADGEL
                     VVGLDTEAFERHCHG"
     gene            14672..15535
                     /locus_tag="P5537_05240"
     CDS             14672..15535
                     /locus_tag="P5537_05240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HRV77484.1"
                     /translation="MNKPLPTSYVQRFLLEDLDIRGAVVRLTDVWEAMQDGRGYAPAV
                     AHLLGEMSAVSTVIAGNLKQPGRLTFQITGHGPVSLLVIDCAETLNLRGYAKAEGTPA
                     AGTLAELVGDGRLQLSLDIEGLDQPYQSLVPLEGDSIAEVFEHYLAQSEQQPARLWLA
                     GSAQAAVALFVQKLPGADAKDLDGWSRVQQLANTVREDELLGLDAEALLRRLFAEENV
                     RLFEARRVTHDWPADPEKIAEMLRALGEDEVRAVLEEHGEVVVHDDLSNHTYRFDRGD
                     VDALFRPPTLH"
     gene            15633..16397
                     /gene="minC"
                     /locus_tag="P5537_05245"
     CDS             15633..16397
                     /gene="minC"
                     /locus_tag="P5537_05245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004857 - enzyme inhibitor activity
                     [Evidence IEA];
                     GO_process: GO:0000918 - division septum site selection
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HRV77485.1"
                     /translation="MSASAPARSIEFHNTTLGATVAVLQAAEPTTLADSLHKMLGGMP
                     DFFNGEAVILDFAGVAQMPARVDWSGLQSLLRRYRLQPIGVMRVPAEHHEGARRAGLA
                     LIDPSQLAGRPPAEAPVQPTPRAEPAAEPVPAPAATTTTPAMFVDRPLRSGQQVYARG
                     TDLVLLGGVSPGAEVIADGSIHCYGPLRGRAIAGAQGDHGARILASNFGPELVSIAGV
                     YRTFERGIPEAFAGKATLVRLTGADHTLNLEALKLD"
     gene            16429..17241
                     /gene="minD"
                     /locus_tag="P5537_05250"
     CDS             16429..17241
                     /gene="minD"
                     /locus_tag="P5537_05250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011765388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0000918 - division septum site selection
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HRV77486.1"
                     /translation="MRVIVVTSGKGGVGKTTTSAAFASGLALRGFKTAVIDFDVGLRN
                     LDLIMGCERRVVYDLVNVVNGEARLNQALIKDKHCDNLFILPASQTRDKDALTEDGVG
                     KVLEELEHMGFEYVVCDSPAGIERGAVMALTFADEAIVTTNPEVSSVRDSDRILGILQ
                     SKSKRARDGGEPVKEHLLITRYSPKRVEDGEMLSYKDVQELLRVPLIGVIPESESVLH
                     ASNQGTPAIHLKGTDVAEAYADVVGRFLGEDLPLRYVNYEKPGLIKRLFGGK"
     gene            17243..17503
                     /gene="minE"
                     /locus_tag="P5537_05255"
     CDS             17243..17503
                     /gene="minE"
                     /locus_tag="P5537_05255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HRV77487.1"
                     /translation="MSFLARLFGEKKKTAEIAKNRLSLLIAHERAGGSPTADFLPALQ
                     RELIEVISKYVAVNPDDIKVHLDKQDNMEVLEVNIVLPEQNR"
     gene            17513..17597
                     /locus_tag="P5537_05260"
     tRNA            17513..17597
                     /locus_tag="P5537_05260"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17547..17549,aa:Leu,seq:taa)
     gene            17667..18125
                     /locus_tag="P5537_05265"
     CDS             17667..18125
                     /locus_tag="P5537_05265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1178 family protein"
                     /protein_id="HRV77488.1"
                     /translation="MIVLDLHCSNEHRFEGWFGSAAAFEEQLARARVSCPVCGSTAIR
                     RLPSAPYVQTGQAATEASPAARAVQAVNAAPPSAPPPEALARLMTQLRGMARAAEDVG
                     ERLPEEARRIHYGETEARDIRGSASADEVESLLEEGILVLPVPPAEEDLH"
     gene            complement(18220..19407)
                     /locus_tag="P5537_05270"
     CDS             complement(18220..19407)
                     /locus_tag="P5537_05270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HRV77489.1"
                     /translation="MAFSIDPGFPLPAGAVLPDYGEGGLFGFARGLRHWLHDRRADWP
                     AAEIAPGERALVVLLLIDGLGERFLDTLGHGSALQKARRGSLSSVCPSTTASAITTLA
                     TGVAPAEHGLNGWFIHDRRFGGVIAPLPLVRRSGEPLEAFRLLPRLFPVAPMYRHACR
                     PVTLVSPAHIAFSRFSLHHGRGAHIEAYDGLDDCVAAIVDMADALAHSGGLIHAYYPV
                     FDLLSHEHGCRSPEAIACFTRLDAAFVQLQQALAGRDVRLLVTADHGFIDAPPERRID
                     LAPDGEVAAMLAAPLFGERRLAFCRVRAGAEGEFEAWAAGELRGKGVAVRSGEFLAAG
                     LLGPGLPHPRLAERLGSHVLLMEAGWTIVDHVPGEHEHAMIGVHGGLSADEMRVPLIL
                     AQT"
     gene            complement(19557..19632)
                     /locus_tag="P5537_05275"
     tRNA            complement(19557..19632)
                     /locus_tag="P5537_05275"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19597..19599),aa:Gly,seq:gcc)
     gene            complement(19706..19779)
                     /locus_tag="P5537_05280"
     tRNA            complement(19706..19779)
                     /locus_tag="P5537_05280"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19745..19747),aa:Cys,seq:gca)
     gene            complement(19852..19927)
                     /locus_tag="P5537_05285"
     tRNA            complement(19852..19927)
                     /locus_tag="P5537_05285"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19892..19894),aa:Gly,seq:gcc)
     gene            complement(20000..20572)
                     /gene="pgsA"
                     /locus_tag="P5537_05290"
     CDS             complement(20000..20572)
                     /gene="pgsA"
                     /locus_tag="P5537_05290"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HRV77490.1"
                     /translation="MPLNIPNALTWARIAMIPVFVGLFYLPESWMPIATQNLVATVIF
                     VAAAVTDWFDGYLARALGQTSAFGAFLDPVADKLMVAAALILLVQLGRVDALIAVVII
                     GREITISALREWMARVGQSASVAVAYVGKLKTTAQMVAIPMLLFNASLYGVDLSLAGE
                     VLIYVAAALTLWSMGYYLRRAMPLLRDTEK"
     gene            20779..22428
                     /gene="pgi"
                     /locus_tag="P5537_05295"
     CDS             20779..22428
                     /gene="pgi"
                     /locus_tag="P5537_05295"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HRV77491.1"
                     /translation="MPAPSSLAAWQSLEQRRLHPLPSLRDRFAADPSRAARMQVGACG
                     MTLDYSKNLLDEHELALLLRLAEEAGVAGRIRAMFDGERINTTEARAVLHVALRCPPG
                     TRWQAGGSDVAADVHAVRARMRAFSLQVRSGEWRGHGGERITDVVNIGIGGSDLGPAM
                     VCEALADHAGDGPRMHFVSNVDGVHIGDVTRRCDPRSTLFVVASKTFTTQETLANANV
                     ARAWIVAAHGDEAAVARHFVAVSTNAAAVRDFGIDTANMFGFWDWVGGRFSLWSAIGL
                     PIALALGPDRFDELLAGAHAMDTHFRAAPPAANLPVLMALLGIWNVNFLGAASQLIAP
                     YHQRLHRLPAYLQQLDMESNGKSVRHDGVAVDCRTSPILWGEQGINGQHAYFQLVHQG
                     TQLVPVDFIGVLDAGREDEGLHRIAFANLVAQAEALMRGKTAAEAEAEMRAAGLPEDR
                     IAALLPHRVFPGNRPSNVLLLDRLDPFTLGALIAAYEHRTFVQGVIWDVNSFDQWGVE
                     LGKQLAARVLAELDPRAVSPSERAHDASTRGLIERYRAHPR"
     gene            22565..23026
                     /locus_tag="P5537_05300"
     CDS             22565..23026
                     /locus_tag="P5537_05300"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047617 - acyl-CoA hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HRV77492.1"
                     /translation="MLAFQDYYPENVAHCYGCGRLNEHGHQIKTFWEGDETVTRYHPR
                     PEHTAIPGFVYGGLIASLIDCHSTGTAAAAAYRAENRPMDSEPPLRFVTGSLHVDFLK
                     PTPMGPELVLRGRVKEIKGRKVVVEAEVWAGEVMTARGEVVAVQMPDTFKA"
     gene            23102..23494
                     /locus_tag="P5537_05305"
     CDS             23102..23494
                     /locus_tag="P5537_05305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HRV77493.1"
                     /translation="MKIAVSSQNFRTVTSHAGKARRFIVFDLATPCTPREVERLDLPR
                     EFALHEYRGLDHPLFAMDAVITGSAGDGFVRRLGARGIEVVLTGETDPLQAVRDYVAG
                     VVKPPLPHEHDHGHAHAHAHGHAHDEAL"
     gene            23770..24162
                     /locus_tag="P5537_05310"
     CDS             23770..24162
                     /locus_tag="P5537_05310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77494.1"
                     /translation="MQNKLLADKYPIHVLELGKNETAHEHLDDLLKAIEARAEADPTV
                     RLIATFDHLSHTQLIGGEIRPDILAAKNLIFCFGVKLLDPTMMAVRPRSIGFAELPDR
                     FVISFLEAPMPEANRKMIEWVTALRKAA"
     gene            24200..24877
                     /locus_tag="P5537_05315"
     CDS             24200..24877
                     /locus_tag="P5537_05315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HRV77495.1"
                     /translation="MYFHPLHSPDSSLIGYLLADLDEQEAVVIDPPPRQTELILALLT
                     ERSLRLCHVLRTHVHRVDAADCSALCDCTSAQLVVGEAAALPQGCSREAVRVAHGTRL
                     VFGNEVVRVLSTPGHTPGCLSYLWRDRLFCGDAFDVGSCCAGDGEADPGALFDTLTRR
                     LFTLPEQTLVFPAHPIKGRHVATLGELRARYAPRLQQSRDGFITDMMQRRPRATTPRI
                     AAPAAGS"
     gene            complement(24879..26084)
                     /locus_tag="P5537_05320"
     CDS             complement(24879..26084)
                     /locus_tag="P5537_05320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HRV77496.1"
                     /translation="MKPALRILAGPVARAQLRERGLTPADVLAVPGAAGGPKGLILNP
                     LDRFLFGHWLAGEGAPVHLLGASIGAWRMASACLPDADTALAEMARHYVEESYLDAEA
                     LAQARASGRPVRQPGAAAVSRAFRARLASHLGGRSDELLRHPRFRLHLFTSRGVHPLL
                     RREGRLRTLVGYAGAYAANLRGRARMGEWLERVVFSDAREALPFAMDDYAGRTCVLGP
                     HNAFEALVASCSIPFWLQAVHDISGAPPGAYWDGGITDYHLHLDYASMLRDAGEALPG
                     GGRGQEGTSMRASEDTLCERPRLVLYPHFQASVVPGWLDKSLRSRHRATARLDNVVLL
                     VPTADWIARLPNAKLPDRRDFKAYGADHAGRAAVWRRAIAESARLADEFAAYVEGGRP
                     IAAEALGEA"
     gene            complement(26110..26565)
                     /locus_tag="P5537_05325"
     CDS             complement(26110..26565)
                     /locus_tag="P5537_05325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77497.1"
                     /translation="MRLAFLCAAVAALCAAPAPILAADDARPQPKLQAPADELPRPAD
                     DRLRAGMLQLRAMVAARVSDPAMDEAAHVALAAEILAQVAAIGEGRDFQGRPGRHLQW
                     LLGDISDGAGLMRDAPRLQAKRLGLLRVAETLNFYGREYDHPGWEPIKP"
     gene            complement(26673..29285)
                     /locus_tag="P5537_05330"
     CDS             complement(26673..29285)
                     /locus_tag="P5537_05330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PEP/pyruvate-binding domain-containing protein"
                     /protein_id="HRV77498.1"
                     /translation="MISPVPQSTVPPTPSAFAPTTGLPGLDAVLRGVARGDNIVWQVQ
                     ALDDYRALVLPYARAARAQGRRLIYFRFAAHPPLLGDDSGAEVFTPRPEDGFDAFVDQ
                     VHSVIEAAGRETMYVFDCLSDLAEAWLSDRMLGNFFRLTCPRLFDLDTVTYFGVLRHR
                     HARAGMDMITETTQYLLDVFRCRDRLYIRPIKVQHRSAAAMNLIHAWEPGDRFRAVAD
                     SGTVAEILAGSGWPGLEDEQIRSRWQQLFDQARTFAALRAAEAPDLAGEAAAFARLAR
                     LLFPDEAGLQELIARYLNVDDLLAVRTRMIGIGTIGGKAAGMLIARAIVRSDAPALHA
                     RLEAHDSFHVGSEVFDTFFVINGLWWVRRRQREAEGFLQGLDGEDGARARILRGRFPE
                     STLRQFEGMLDYFGEWPFIVRSSSRLEDRYGNAFAGQYDSVFCANRGTREERLAALLD
                     AVRQVYASTLSESALRYRERRGLLDEHEQMALLIMRVSGTAGGRWFNPHAAGVGLSVN
                     PYPWNPRIDMKAGVVRLVAGLGTRAVDRADDDYTRLIALDAPELRPETSFGAIARHAQ
                     RRMDSLDLERGEVVSGPFAELVRGHADFPHALFTTREAEDRPAFLTFDGLIASTDFVA
                     DLRTLLRTLHAAYAHPVEIEFALNFVPDGGYRINLLQCRPMQVRSVEGVQGVEPPAGV
                     ARLLEARGAVIGPSRVIRPERIVLVRPAAFAALDQPRRLAVTRVLGRLNALAGGRCVL
                     MLGPGRWGSKDPFLGIPVLFSEINHVAALCEIVAMHEHLVPDVSLGTHFLNELIEADL
                     LYFALFPKMAGNALDEAGILRWPNRLGELLPEDADWSAVVHVADPAPDRPVLYADAPG
                     QRVTVTVEEAGSAT"
     gene            29541..29999
                     /locus_tag="P5537_05335"
     CDS             29541..29999
                     /locus_tag="P5537_05335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c"
                     /protein_id="HRV77499.1"
                     /translation="MPRTNAARTLLLALPAALLLACSSEPPDTHPDKPVTQRREAFKA
                     MLRSTEPMGTMLKDRRFDADRFASLADQLAAARETPWKHFGADTNYPPTKARPAVWEK
                     PDEFERRRSEFISATDRLLAAAAARSEDQARSALAAVQDSCKACHKDFRR"
     gene            complement(30193..31233)
                     /locus_tag="P5537_05340"
     CDS             complement(30193..31233)
                     /locus_tag="P5537_05340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940541.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HRV77500.1"
                     /translation="MSSAPTFVSALHSDPIPDSDGTARAAASPFGERRYNAWNDHVKR
                     RWGGRVQKVSVAAGFTCPNRDGTVGSGGCTFCNNAGFTPGYLDRRDPIGEQIDAGLRF
                     LDRRYPGTQRFIAYFQTYSNTYGEFARLREIYETALAHPRVSGLAIGTRPDCLPDAVL
                     DYLAELAREHIVELEIGVESCDDEVLRRINRGHDFACSEHAIRRAAARGLGVTAHLIL
                     GLPGETRAGMLEAAGRLSALPITALKLHQLQLVRGTAMARDWERDPASVPLLAEDEYM
                     ALLADFVERLSPTILLQRLGSEVPPALKLAPQWNIRLSELAPRLSAELARRDSWQGRL
                     HEAASEPLDDRP"
     assembly_gap    31531..31630
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(31773..32375)
                     /gene="petA"
                     /locus_tag="P5537_05345"
     CDS             complement(31773..32375)
                     /gene="petA"
                     /locus_tag="P5537_05345"
                     /EC_number="7.1.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045275 - respiratory chain complex III
                     [Evidence IEA];
                     GO_function: GO:0008121 - ubiquinol-cytochrome-c reductase
                     activity [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_process: GO:0009060 - aerobic respiration [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinol-cytochrome c reductase iron-sulfur
                     subunit"
                     /protein_id="HRV77501.1"
                     /translation="MSDTPSELAAQRRKLLIATSAAGAVAAGATAIPFVASLTPSDRA
                     RAAGAPVEADVSKLAVGDMMTVEWRGKPVWILRRTPEMLATLEQNEARLADPGSGEPQ
                     QPDYATNRHRSIKPEYLIVIGICTHLGCSPSEKFATGTTEGMTADWPGGFLCPCHGSI
                     FDLAGRVYLSQPAPTNLEIPPHKWLSDGLVLIGEDDHGTA"
     gene            complement(32711..34108)
                     /locus_tag="P5537_05350"
     CDS             complement(32711..34108)
                     /locus_tag="P5537_05350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HRV77502.1"
                     /translation="MPPETRPLPELVSFLETLPEPHILCDRDYRIIAANAAYRRSWPE
                     ARSVIGRTCYDVSHHYSVPCDRAGESCPLARSLQSGQRERVLHLHHTPRGEEYVNIEL
                     SPVRDASGEIAWFIEKMEPMHVARGVSDHRGLIGRSPAFQRMLELIARVAPSDASVLL
                     QGESGTGKELLASAVHEASRRAEGPFVVVDCSGLPETLFESEVFGHERGAFTGATARK
                     PGLVEAASGGTLFLDEVGDIPLGMQVKLLRLLETGTYRRVGSTELRRADIRLVSATHR
                     PLKRMIAEGGFRQDLYFRINTFPITVPPLREREGDLPLLIDSLLERVAPKRTLSLGPA
                     ALRVLCDYPFPGNVRELRNVLERASLMCDGEVIGPEHLPEEVLHPERESAGSRFASGG
                     PPAAAVPVRDPLDLEEVQRQAMLRAVRAHRGSRRELARRLGISERTLYRRLKALGLLE
                     GEGGEGDEKKSPQGS"
     gene            34282..34479
                     /locus_tag="P5537_05355"
     CDS             34282..34479
                     /locus_tag="P5537_05355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77503.1"
                     /translation="MNPTDRRLVREITLVIVLKLILITALWWAFIRDAKVAVDPGAMA
                     AQVVAPASTKQHSTSGESHGQ"
     gene            34469..36031
                     /locus_tag="P5537_05360"
     CDS             34469..36031
                     /locus_tag="P5537_05360"
                     /EC_number="1.10.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0070069 - cytochrome complex [Evidence
                     IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_process: GO:0019646 - aerobic electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome ubiquinol oxidase subunit I"
                     /protein_id="HRV77504.1"
                     /translation="MVSEQLVDLSRLQFAATAMYHFLFVPLTIGMVWMLVIMESVYVM
                     TGKTIYKDMTRFWGKLFGINFALGVTTGLTLEFQFGTNWAYYSHYVGDIFGAPLAIEG
                     LMAFFLESTFIGLFFFGWDRLSRQQHLLVTILMAVGTNLSALWILIANGWMQNPVGSE
                     FSYETMRMELTDFWAVVFNPVAQGKFVHTVSAGYVTGAMFVLSISAWYLLRGRDVEFA
                     KRSFRIAAAFGFASICSVIVLGDESGYALGEAQQTKLAAMEAMWETEPAPASFNVIAV
                     PNEAEMKNDFAIHIPWVMGLIGTRSLDKELPGLNQIYALNRERVKVGVEAVKLLEALR
                     KSPQDAALREAFDRVKDDLGFGLLLKKYAASMDDVTPELIDRAARDTLPKVTPLFWTF
                     RIMVALGFAMLALFGLALWYSIKGDFAQRPWLLRWALWFLPMPWISCEMGWFVAEYGR
                     QPWTIYGVLPTHLSVSTLTVNSLYGSLAGFVGFYTLLLIVEMYLMVKFARQGPGSLGT
                     GRYLNETHHAHA"
     gene            36048..37190
                     /gene="cydB"
                     /locus_tag="P5537_05365"
     CDS             36048..37190
                     /gene="cydB"
                     /locus_tag="P5537_05365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016682 - oxidoreductase activity, acting
                     on diphenols and related substances as donors, oxygen as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HRV77505.1"
                     /translation="MIFDYPTFKIIWWLLVGVLLVGFAIMDGHDMGVGTLLPFVGRND
                     EERRVVINTVGPHWDGNQVWFITGGGAIFAAWPIVYATAFSGFYWAMLAVLWALFFRP
                     VGFDYRSKIHNATWRSTWDWGLFIGGAVPPLIFGVAFGNLLQGVPFHFDDTLVPYYTG
                     SFWGLLNPFALLAGVVSTAMITFHGAIYLAHRTEGDIQRRATTAALIFGVLMLVGFTA
                     AGLWIANGSFGYAITSVLDTAALPNPLAKTVELQPGAWLANYDKAPLTMLVPALAYAG
                     GLAALLLVWKGRTLAAFVASSFAIIGVIGTAGVSMFPFVMPSSTVPGASLTVWDAVSS
                     HRTLGIMFWATVIFMPIIVAYTSWAYSVMAGKVTAAYIRENEHSAY"
     gene            37218..37301
                     /gene="cydX"
                     /locus_tag="P5537_05370"
                     /pseudo
     CDS             37218..37301
                     /gene="cydX"
                     /locus_tag="P5537_05370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000270285.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016682 - oxidoreductase activity, acting
                     on diphenols and related substances as donors, oxygen as
                     acceptor [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-I oxidase subunit CydX"
     gene            37381..37722
                     /locus_tag="P5537_05375"
     CDS             37381..37722
                     /locus_tag="P5537_05375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004333695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyd operon YbgE family protein"
                     /protein_id="HRV77506.1"
                     /translation="MKPHASTFATAEDASLGLDGPAPSSEATRIRLLPLLLAIAVMLG
                     ITAWPGALAGPSGAADHLAAMALFWAMSAGFVAGVGFRPRKLLIRLLLSPLACWLGVI
                     LAGLRLASLTA"
     gene            37857..38864
                     /locus_tag="P5537_05380"
     CDS             37857..38864
                     /locus_tag="P5537_05380"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF019604.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="HRV77507.1"
                     /translation="MKDLPKSPPELPAIDPERRRLLLGASALPLAAGAGLSLAPTRAR
                     AALKTSARIVIAGSGLAGVAAANRLARELDGAKITIVDRKEIHNYQPGYTLVATGVWP
                     VEKVSDRNADLIPPGVEWVREMVAEFDAEKNAVVTDGGRRIEYDFLIVATGLHMDFGL
                     IEGMDVAAIGRNGLASVYPSPQAAQATWQAMDTFRQKGGKALMTLPATPLKCAGAPLK
                     MTFMVVDRLRQAGTRDQSQVSFHSALDNIFSVPRINQEVLERWKKLDVPVHFLSKLVA
                     VDIGARRATFASPEGERTQHDYDFIHVVPPMRAPDSVKNSPLSWKQGPFAAGGTTWMK
                     S"
BASE COUNT         6100 a        13608 c        13093 g         5877 t
ORIGIN      
        1 taggcgctgt gcttgtggta gctcgagtgc gccaccgaga tgccgatctc gtgcaacatc
       61 gccgcccagc gcaggaagcg gtggtcgtcg tgctcgggat cggcggtctc cggttcgagc
      121 tgggcgagca ggtggcaggc ggtgtcggcg acctgctggg cctggcgcag gtcgacgccg
      181 tagcggcgca cgaaggcgct cacggtggcg tcgcgcaggt cgtggtggtg gtagcgcccg
      241 agcaggtcgt agagcacgcc gaggcgcagg gcgccttcgg agaacaccat gtgctcgagc
      301 tcgaactcct tgaagatcgc gctcatgatc gcgaagccgc cgaggatcac cggcaggcgg
      361 tcgcccttga ggccggcgag gtcgatgttg tccaggctcc ccgcgcgcag cagcagcgcc
      421 ttgagcttct ccagaccctc gcgcgtgatg ccgcccttcg agagcccgtt ctgctcgagg
      481 atctcgacga tcgccttggc ggtgccgctc gagcccaccg cctcctccca gccggcctcg
      541 cggtaggccg ccgagatcgt ctgcagctcg cggcgggcgg cgagctcggc ctccttgaag
      601 gcgcgtttgt cgatgcggcc atcgggaaag tagcgcaggc tgtagccgac gcagcccatg
      661 tagcgcgatt cgagcaattg ggactcgaag ctcttgccga cgatgaactc ggtggagccg
      721 ccgccgatgt cgaccacgag ctgctggcgg tgcggatccg ggagcgtgtg cgcgacgccg
      781 acgtagatca ggcgcgcctc ctcgcgaccg gcgatgatct cgatcgggaa gccgagcgcg
      841 gcctcggcgc ggatcaggaa ctcgggcgcg ttcttggcca cgcgcagggt gttggtcgcc
      901 accgcacgca cccgggtggg cgggaagtcg cgcaggcgct cgtggaagcg ctgcagggcg
      961 gcgacgccgc gttgctgcga ggcgagatcg agcatcttgt cgggagacag gcctgcagcc
     1021 aggcgcaccg cctccttcaa accatcgagc ggatagatct ggtcattgac gatgcggccc
     1081 acctgcagcc ggaaactgtt ggaaccgagg tcgattgcgg cgatcagatc ttgcattgtg
     1141 gtttcggcag ctggcacccc agggcgccgg aattcggaat tctaacatcc cgcaaaagcc
     1201 ttccgagcca cgccggggct gcatttgcgg tcccggcgga aggcgtccgg gcggtcatga
     1261 aaccgcaatg gaaatgtcac ataatcccaa gtgaacttcc gcgcacagga accccgaatg
     1321 cacgccgatc gcatgcccct gaactactct tccgaacact tcctgaaccg cgagctctcg
     1381 ctgctgcaat tccagcgccg cgtgctggcc caggccgccg accccaccgt tccgctgctc
     1441 gaacgcctgc gcttcctgtg catcgtgtcg agcaacctcg acgaattctt cgagatccgc
     1501 gtctccggca tcaaggagca gctccgaatc ggcagccgca agtcgggcga ggacggcatc
     1561 gcgcccgccg aactgctcga gcgggtgagc gacgaggtgc acgagatcat ctccgagcag
     1621 taccagctgc tcaacggcga cattctcccc gcgctggaga aggaaggcgt ggtcttcccg
     1681 cgccgcagcc tgtggaccga ggcccagcgc gcgtggatcc acgactactt catgcgcgag
     1741 gtcatgccgg tgctgacgcc gatcgggctg gacccggcgc accccttccc gcgcgtgctc
     1801 aacaagagcc tgaacttcgc cgtcgagctc gagggccgcg acgccttcgg gcgcgactcg
     1861 ggcgcggcga tcgtgcaggc gccgcgtgcg ctgccgcgcg tgatccgcct gccgcgcgag
     1921 ctgtgcgagc aggagtacgg cttcgtgttc ctgtcctcgg tgctgcacgc ccatgtcggc
     1981 gagctgttct cgggcatgaa cgtgctcggc tgctaccagt tccgggtcac ccgcaactcc
     2041 gacctcttcg tcgacgagga ggaggtcaag gacctgcgca cctcgctcaa gggcgagctg
     2101 cagcagcgcc acttcggcga cgcggtgcgg ctcgaggtgg ccgacaactg ctccgaggag
     2161 atggcgggct tcctgctcca gcacttccat ctgacccccg acgacctcta tcgcacgccc
     2221 ggcatcgtca acctggtgcg cctgatgcag gtccccgact gggtcgagcg tccggacctc
     2281 aaatacagcc ccttcgtgcc cggtctgccc aaggtgctcg acaagcgccg ccaggtgttc
     2341 accgcgatcc gcggtggcga catcctcctc caccacccct tccagagctt cgccccggtg
     2401 atcgagatgc tgcgcgctgc ggccgatgac ccgcaggtgc tggcgatcaa gatgaccgtg
     2461 taccgcaccg gcaccgactc ggtgctgatg gaacacctcg cgcgcgccgc gcagaagggc
     2521 aaggaggtca ccgttgtgct ggagctgatg gcgcgcttcg acgaggaggc caacatcacc
     2581 ctggccaacc gcctcgaaga ggtcggcgcc cacgtcgtct atggcgtgtt cggctacaag
     2641 acccacgcca agctgctgat gatcgtgcgc cgcgaggaag acggcctgcg ccgctacgtg
     2701 cacatgggca ccggcaacta ccacccgcgc acgacgcgct tctacaccga cttcggcctg
     2761 ctcacctgca accaggagat cggcgaggac gtcgcggcgg tgttcaagca gctcaccggc
     2821 ctgggcaagg ccaccgagct gcgccacctg tggcaggcgc cgttcacgct gcagccgaac
     2881 gtggtcgcgg ccatccgccg cgaggccgag atcgcgcgcg agggccggcg tggccgggtg
     2941 atcgccaaga tgaacgcgct gctcgagccg gagaccatcg aggcgctcta cgaggcctcg
     3001 caggccggcg tcgaggtcga cctgatcgtg cgcggtccgt gcgcgctgcg cccgggcgtg
     3061 cccggcctgt cggacaacat ccgcgtgcgc tcggtggtcg gacgcttcct cgaacaccac
     3121 cgcatcttcc acttccacgc cgacggcgcc gagcacatgt acctgtcgag cgcggactgg
     3181 atggatcgca acttcttccg ccgcatcgag atcgccttcc cggtgctcga cccgcgcctc
     3241 aagcgccgcg tcatgaagga aggcctgcgc ccctacctcg gcgacaactg ccaggcctgg
     3301 gacatgcagc ccgacggcaa gtaccgccgc aagcacccgc gcagcatccg ccgcgcggcg
     3361 cagctcatcc tgctgaagga gctcgcggcg agcagctgac cggactcgcc cggggcgccc
     3421 gccaggaaag gttgcgcgcg cccccgcccc cgcccccgcc gcagcctcgg cacgccccta
     3481 cttgcgctgc gcgtcgatta cgcccggcac ctcgcgcacc agggtgatcg cgcgctgcac
     3541 ctgcttgatg ccgccgacct ccatggtgaa gcgcatgtnn nnnnnnnnnn nnnnnnnnnn
     3601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3661 nnnnnnnnnn nnnnnnnngt gatcgcgcgc tgcacctgct tgatgccgcc gacctccatg
     3721 gtgaagcgca tgtaggcggt gcccttcttg gtcagggtgt tgaccgcgat cacgttgagc
     3781 ttctcgcgcg acagcacctc ggagatgtcg cgcagcaggc cctggcggtc gctcgcctgg
     3841 acgttgatgt cgacctggta gagcgcgttg cgggtgtcgt gcgccttctc gccccactcg
     3901 gccgggatca cgcgctcggg gtgcttgcgc gcaagatcct ggaagtcggc gcagtcgacg
     3961 cgatggatcg agatgccgcg accgcgcgtc acgaagcctt cgatcgcgtc cggcggcgcg
     4021 ggcttgcagc agcgcgacag cgaggtcatc agcttgccca cgccatcgat gaggatcttg
     4081 tcctggttgt cgccggagcg gctgcggctg cggctgacca cgaactcggg ctcggcctcg
     4141 gccgcgggct cgggcgcgtt gccctcgcgc agcgcggtct gcatcgcgcg cggccccacc
     4201 tcgccgcgcc cggcggccag gtagagcgcc tcggcgttct tgaagcccag gcgatccgcg
     4261 aggccgtcga tgttggcctg gccgtggccg tcgcgctgca tctccttggt gacgaagttg
     4321 cgcccgcgcg agaggatctc ctcctcgtcg agctgggcga agtattgctt gatcttgctg
     4381 cgcgcacgcg aggtggcgac gtagccctgg cgcacgtcca gccagtcgcg cgaggggccg
     4441 ccctccttgg cggtgacgat ctcgaccgtc tgcccgctct cgagcggcgt gttgagcggc
     4501 acgaggtggc catcgacctt ggcaccacgg cagtggtggc cgacgtcggt gtgcaggcgg
     4561 taggcgaagt cgatcggcgt ggcgccgcgc ggcaggtcga ccaccctgcc ctgcggggtc
     4621 agcacgtaga gcgtatcgtc tagcgaggcg cgcttgagct gctccaccca gtgcgcggcg
     4681 tcggtgacct cgtcgcgcca cgacagcagg ttgcgcagca gcgcgatctt ctcgtcgtag
     4741 tcgccgccct gcctggcgcc ttccttgtag cgccagtgcg cagccacgcc gagctcggca
     4801 tgcttgtgca tgtcgaaggt gcggatctgc acctcgagcg cgcgcccgtc gccggccagc
     4861 accgcagtgt gcagcgactg gtagttgttg cccttgggct tggtgatgta gtcgtcgaac
     4921 tccttcgcga tcggctgcca catctggtgc acgatgccga gcacggtgta gcagtccttg
     4981 atctcgggca ccagcacgcg cagcgcgcgg atgtcgaaga cctgcgagaa gtcgagccgc
     5041 ttcttgcgca tcttgttgta gatgctatag atgtgcttgg cccgtccggt gatctcgcct
     5101 tcgatgccca ccgcggcgag ctcactcctg aggcgctcga tcgagtcgtg gatgaactgc
     5161 tcgcgctcga cgcggcgctc gtcgagcatc ctggcgatgc gcttgtaggt ctcgggctcg
     5221 atgaagcgga aggagaggtc ctcgagctcc cacttgatct gccacacccc cagccggttg
     5281 gcgagcggcg catagatgtc caggctctcg cgcgccacct cgacacgggc ctcgcccggc
     5341 agatcggtgt agaagcgcag cgtctgcgtg cgcgaagcca gccgcaccag cacgacgcgg
     5401 atatcctcga ccatcgccag cagcatcttg cgcaggacct cggtctgcgc acgaatctcg
     5461 ggcgcgctcg cgttggtggt gaggcgggtg agcacgcgca ggccgttgag cttgtgcagg
     5521 ccgcgcacca gcgcggtgat cgccggaccg aagcgggcct cgatctcctc ggccgggtcg
     5581 tcgagctctt cccaggcggc gaacagcaac gcggccatcc gcgtctcggc atcgaggcgc
     5641 agcgaggcgg caatcagcgc ggcgccgatc gcatgtgtcc aggtcggctc gccggtgccc
     5701 aggaccttgc cctcgtagag gtcggcgatc cattcgagcg cggcttcgat gcgcccgcgt
     5761 tcgcccacct ccaggccggc ggcaagcaga tcgatcgggg gggcggtgtc gccctgtgag
     5821 atggcgtggg tgacggaaac catggcacgg attatcccac atcgggcaga aatcgaccct
     5881 ccccgggagg gctgccgcgg gtgctgaacg cggtccgccc gacttgcatg cgcgccgccg
     5941 gcgggcaatc atccagcgcg cgcccatccg cttctccgga ctccccatgc tccagatcct
     6001 gcgtcgcctg ctcggcatcg cgcccgcccg ccccacggtg gatgcggcgc aatgggcgcg
     6061 ggtggaggcc cgcctgccct tcctcgacca cctcgacccg accgaccgcg cacacttgcg
     6121 cgagatggcg ctcgccttcc tggccagcaa gcagttccat ggcgcacaag gcctcgaact
     6181 ggacgacgac atgctgctgg cgatcgcgct gcaggcctgc ctgccggtgc tccacatcgg
     6241 gctgcaggcc tacgacggct gggtcggggt gatcgtatat ccgggcgact ttctgatccc
     6301 gcgacgcatc gtcgacgagg ccggggtgct gcacgaatac gaggacgagg tgctcggcga
     6361 ggcctgggag ggcgggccgg tgctgttgtc ctggttcgcc ggcgaggacg ggcctgcagg
     6421 catcaacgtg gtcatccacg agttcgccca caagctcgac atggagaacg gcggcgtcga
     6481 cggcctgccc cgcctgcgcc ccggcatgtc ccgccacgtc tgggccgagg ccttcggcaa
     6541 ggcctacgag gacttttgcg ccgaagtgga ccgcggcggc gagaccgcga tcgatcccta
     6601 cggcacagag cacccgggcg agttcttcgc ggtggtctcc gaggtcttct tcgaggcccc
     6661 gctcaccctg cgcgatcgct ttcccgcggt ctacgatcaa ctcgcgcagt tctacggcat
     6721 ggaccctgcc gcccgcgcgg cgcccaccag cggaggctga aatgagcacg cccaaacgcc
     6781 tgctgatcgt ccaccacacc cagagcggca acaccggccg cctcgccgcc gcggtgcacg
     6841 aaggggcgca gcgcgtggcc gagaccgaga cccggctgct gcgcgccttc gacgcgggca
     6901 ccgccgacct cctcgcctgc gacggcctgc tgctcggcac gccggagaac ttcggctaca
     6961 tgtcgggcgc gctcaaggac ttcttcgatc gcacctacta cccctgcgag ggcaagctcg
     7021 tcggcctgcc ctatgcggtc ttcgtcagcg ccggaaacga cggcaccggt gcggtccgcg
     7081 agatcggccg catcgccaac ggatacggct ggaagacggt cgccgaggcg ctgatcgtgc
     7141 ggcgcgagat cacccccgcc gacctcgagc gcgcgcgcga gctcggcgag gcgatggcgg
     7201 ccgggctggc gatgggggtg ttctgagggc gcgaggcgcg aggggtctcg ggcgcgagga
     7261 gcgctggaga cgcggctgaa gctggctcga gcgcgcagtg gaagttcacg tttgcgttaa
     7321 ccgggatcga ctttcacgaa gcggtaacga tcgtcatggc ggagtcgatt cacgtggcct
     7381 aagctgcaat cgtgtccgcc gcggcgggca ccccggtctt taatcgaacg gaggattgct
     7441 tatggccatc acctggattc tggttgccaa cgccagcctg gcaaagctct acgccaacct
     7501 gggccccaac aagggcctta cgctggtgaa ggaactgatc cacccggaaa gcagacagaa
     7561 gaacggcgac ctggtctcgg accgcgcggg cgcgaatggc tcgaacggca ccggcggcgg
     7621 ctcgatgcag ccgcagaccc tgcccaagca gcacgaggcc aaggtgttcg cacaggagct
     7681 cgcccagacg ctctaccagg gccgcaccag caacgcattc aagcgtgcca tcctggtcgc
     7741 cccgcccgca ttcatgggcc tgctcaatgc cgtcctcgac ggcccgaccg cgcagatggt
     7801 cacagaccga ttcgaaaagg attacaccaa gacaccgcag gacgagctcg ggcaacatct
     7861 cggctcgacg atctttctct gagggaggac tttcccgaag gctccaaacc cgatcagcca
     7921 atggcgaagg gcagctgccc gagccaagga ggatgtgctt gaccgagacc ccgaggatgc
     7981 agctttcctg acgaacgcag caaacctgaa cgacatcgtc tccactacgg agaccgaggg
     8041 cacgcgtagc gtggcccgac ccaggacggg gcgcaacgcg ccccgttcgc cattctgacc
     8101 gacaggttcg cggttgcccc cggcgcagca ggggcgcggt gcggaagacg ggctcagctc
     8161 gtgccgcgtc cgtaggtgtc ctcgaagcgg acgatgtcgt cctcgccgag gtagctgccg
     8221 gactggacct cgatgatctc gagcgggacc ttgccgggat tcgacaggcg gtgggtgtgg
     8281 ccgagcggga tgtaggtcga ctcgttctcc gcgagcagga agctgcgctc gccgttggtg
     8341 acctcggcgg tgcccttgac cacgatccag tgctcggcgc ggtggtggtg catctgcagg
     8401 ctgagcttgg cgcccgggtt gaccacgatg cgcttgacct ggaagcgctc gccggcgtcg
     8461 atcgagtcgt accagcccca tgggcgatac accttgcgat ggctctgcgt gagcgtgcgg
     8521 ccctcggcct tcaggcgcgc cacgaccttc ttgacgtcct gcgtgcggtc cttgtgcgcg
     8581 accatcaccg cgtcgggcgt ctcgacgacc accatgtcct cgcaacccac cgccgcgacc
     8641 aggcggctgc cggcgtgcac cagggtgttg cggcaggcct cgaagagcac ctcgccgcgc
     8701 gcggcgttgc cctcgccgtc cttggccgac accgcccaca gcgcgtccca ggcgccgacg
     8761 tcggaccagc cggccgaaag cggcacgacc acgccctgcc ccagctcggg cgcttcggcg
     8821 agcttttcca tcaccgcgta gtcgatcgag tcgctcgggc tgcgctcgaa ggcggcggtg
     8881 tcgaggcgga tgaagtcggc gtcatgggtg cagcccccca ccgcggccgt gcacgccgcc
     8941 gccatctcgg gtgcgaagcg gcggatcgcc gccagccaga ccgaggcctt catcatgaag
     9001 atgccgctgt tccagtagta ggcgccgctg gcgacgtagg cctcggcggt ggcgcggtcg
     9061 ggcttctcca cgaattccag cagggcgcgt gcgccctcgc cctcggccag cgtgacgccg
     9121 ctgcgaaggt agccgtagcc ggtctccgcg cggtcgggca cgatgccgaa ggtcaccagc
     9181 gcgcccttcg cggccgcctt cgcgccgacc gcgatcgcgt gctggaaggc aggctgttcg
     9241 gtgatgacgt ggtcggcggg catcaccagc aggatcgggt cgccctcgtc cgccgccacc
     9301 agcgcagcca gggtgagcgc cggcgcggtg ttgcgcccga ccggctcgag cacgatctgc
     9361 ggcgaacgta cgccgatctg gcgcagttgc tcggcgatga tgaagcggta ctcctcgttg
     9421 gtgacgacca gcgggcgcgg gtcgacctcg ccaccgggga agtccttcag ccgcagcgcc
     9481 gtctcctgca gcagcgagcg ctcgctggtg agcggcagga gttgcttggg ataactctcg
     9541 cgcgaggccg gccacagccg ggtgccggaa ccgccggaga ggatcacgct cttgatggtc
     9601 atgaatcagg tccttgcgtt gttctgtctg tcggctgctt cagtcgagga tctcgcgcag
     9661 catgcgggcg acgccgtcgc gccagtcggg cagcgcgagc tcgaagcgct cgcgcagccg
     9721 cgcgctgtcg agccgggaat tgagcggccg cactgcagcg gtcggatagt cgcgcgtgcc
     9781 gatcggggcg atctcgctca ccttcagtgt cgcgccgagt tcgcgcgcct gctcgatcac
     9841 gaagctcgcg tagccgtgcc agctcgtctc gccgctcgca gcgaggtggt aggtaccgcc
     9901 caggccgtgg ttggcgcgct cggcgcggat ggcgtgggcg ctgacgtcgg cgatcaactc
     9961 cgcgccggta ggcgcgccgt gctggtcggc gatcaccgtc aggcgttcgc gctcggcccc
    10021 cagccgcagc atcgtgcgtg cgaagttgcc gccgcgcgcc gcatacaccc aggatgtacg
    10081 caggatcagg tggcggcagc ccgcggcgcg gatcgcctct tcgccggcga gcttggtgcg
    10141 cccgtagacc gacagcggcg cggtcgcagc gtcctcgcgc cagggggtgt cgccgctgcc
    10201 gtcgaagaca tagtcggtcg agtaatgcac cagcagcgcg cccaccgccg cagcggccac
    10261 ggcgagcacg cccggcgcct cggcattgac gcgctgcgcg cgctcgacat cggtctcggc
    10321 cttgtccacc gcggtgtagg cagcggcgtt gacgatcacg tccgggacga tccggcgcac
    10381 cgtgcggtcg aggccgtcga gatcctcgag gtcaccgcgc aggccgtcgg cgccgccacg
    10441 gtcgagcgcc acgacgatgc cgagcggcgc gagcgcgcgc tgcagttccc agccgacctg
    10501 gccgttcttg cccagcagca ggatcttcat ccctgcacct cgcgtccggc gtagttgcgt
    10561 gccacccagt cgcggtaggc gccgctctgc acgttggcga tccagcccgg gttgtccaga
    10621 taccattgca ccgtcttgcg gatgcccgtc tggaaggtct ccgcggggcg ccagccgagc
    10681 tcgcgctcga tcttgtgcgc gtcgatggca tagcggcggt cgtggccggg acggtccttc
    10741 acataggtga tcaggcgggc gtagctgccg tcggcatccg ggcgcagctc gtcgagcagt
    10801 gcgcaaagcg cgtgcacgat gtcgatgttg gccatctcgt tccagccgcc gacgttgtag
    10861 gtctcgccga ggcggccgcg ggcgagcacc tcgcggatcg cgccgcagtg gtcgcccaca
    10921 tacagccagt cgcgcacgtt ctggccgtcg ccgtagatcg gcagcggctt gccggcgagc
    10981 gcgttgacga tcatcagcgg gatcagcttc tcgggaaact ggtagggccc gtagttgttc
    11041 gagcagttcg tggtgagcac cggcagtccg taggtgtggt gccaggcgcg cacgaggtgg
    11101 tcactcgccg ccttgctcgc cgaatacggg ctgttgggct cgtaggcctt cgtctcggtg
    11161 aaggcggggt cgttcgggcc gagcgagccg tagacctcgt cggtgctcac gtgcaggaag
    11221 cggaaggcct cgcgctcgcc ggcgggcagc gcgctccagt gcatgcgcgc cgcttcgagc
    11281 agcgtgaagg tgccgtcgac gttggtgcgc acgaaggcgc cgggcccatg gatggagcgg
    11341 tctacatggc tttcggcggc gaagtgcacc accgcgcgcg gcttgtgctc ggcaaagagg
    11401 cgttcgacca gggcacggtc gcagatgtcg ccatgcacga agaggtgacg cgcgtcgccc
    11461 tccagcggcg caagggtctc gcggttgccg gcgtaggtca gcgcatcgag gttgatcacc
    11521 ggctcgtcgc tggccgccag ccagtcgagc acgaagttcg cgccgatgaa gccggcgccg
    11581 cctgtcacga gaatcactct gggaaccctg cctgaagcgt aaagcctgaa ttatggcatc
    11641 cggtagctgc cattccgagt gtccgatttc tcgcactccg gcgattgggt gcggtcgagc
    11701 cgccctgcgc cccccggact tcccgtgcat ccggacgcca gttcccgcgc gccggagccc
    11761 tcaccgcctg ccgggcgggc gttcgagcat cgttcgtgag cgtccgctca gtgcggttgc
    11821 tctacccgcg ccgcctgttg cactatcccg ccctcccctt ttgcgcttca ccgcctctcc
    11881 cccatgctcc ccccgatcga acatcgcatc gccgaagagc tcggcgtctc gccgcgccag
    11941 gtcatcgccg ccgtccagct catcgacgac ggcgccaccg tgcccttcat cgcccgctac
    12001 cgcaaggaag tcaccggcgg cctggacgac acccagctgc gcacgctcga agagcgcctg
    12061 ggctacctgc gcgagctcga ggaccggcgc gcgaccgtgc tggcctcgat cgaggagcag
    12121 ggcaagctca gccccgagct gcgtgccgag gtcgaagacg ccgacaccaa gcagcgcctc
    12181 gaagaccttt acctgcccta caagcccaag cgccgcacca aggcgcagat cgcgcgcgag
    12241 gccggcatcg gcccgctcgc cgaagccttg ctcgccgacc ccgcgctgac acccgaagtg
    12301 gaggcagagc gctacctgaa tgccgagctc ggcttcgccg acaccaaggc ggtgctcgac
    12361 ggcgcacgcc agatcctgat ggaacacttc gccgaggacg ccgccctgct cggcgaactg
    12421 cgcggctacc tgcacgagca cggcctggtg cgctcgcgcg tgatcgatgg caaggagaac
    12481 gagggggcca agttccgcga ctggttcgac ttcgccgagc ccatcgccac catgccctcg
    12541 caccgcgcgc tcgcgttgct gcgtgggcgc aacgagggcg tgctgcgcct tgcgctcgac
    12601 gtcgaccgtc cggaccccga cgcgccgcat ccctgcgagg gccgcatcgc ggtgcgcttc
    12661 ggcatccgca accaggggcg cccggccgac cgctggctcg ccgagaccgc gcgctgggcg
    12721 tggagcgtga agatctccat ccacctcgag ctcgagctga tgagcgagct gcgcgaacgc
    12781 gccgaggaag aggcgatccg cgtcttcgcg cgcaacctca aggacctgct gcttgccgcg
    12841 cctgccggca cgcgcgccac catcggcctc gacccgggca ttcgcaccgg cgtgaaggtc
    12901 gcggtggtcg atgccaccgg caagctggtc gacaccgcca ccgtgtaccc cttcgagccg
    12961 cgccgcgacc gcgagtcctc gatcgccacc atcgccgcgc tggcgcagaa gcacgccgtc
    13021 gaactcatcg ccatcggcaa cggcacggcc tcgcgcgaga ccgacgcgct ggtggccgag
    13081 ctgatgaagc gccaccccga gctgccactg acgaagatcg tggtgtcgga agccggcgcc
    13141 tcggtatatt ccgcatccga gctcgccgcg cgcgagttcc ccgagctcga cgtcagcctg
    13201 cgcggcgcgg tgtcgatcgc ccgccgcctg caggacccgc tcgccgagct ggtcaagatc
    13261 gaccccaagt cgatcggtgt cggccagtac cagcacgacg tcaaccaggg ccgcctcgcc
    13321 aagagcctgg acgcggtggt ggaagactgc gtgaacgcgg tcggcgtgga tgtgaacacc
    13381 gcctcggcgc cgctgctggc gcgcatctcc gggctcaacg ccaccctcgc aggcaacatc
    13441 gtcgagtacc gcaacaccca gggccccttc cgcagccgca gcgccctgaa ggaagtgcct
    13501 cgcctcggcc ccaagacctt cgagcaggcc gccggcttcc tgcgcatccc gagcggcgac
    13561 aacccgctcg atgcctcgtc ggtgcacccg gaggcctatc cggtggtcga acgcatcctc
    13621 gccaaggtgc agaagggcgt gcgcgaactg atgggcaacg gcagcttcct gaagagcctg
    13681 aagccggcgg agtttaccga cgagcgcttc ggcctgccca cggtgcagga catcctcgcc
    13741 gagctggaga agcccggccg cgacccgcgc cccgagttcc gcaccgccac cttccgcgag
    13801 ggcgtggaga ccttgaagga cctcgagccc ggcatgctgc tcgagggcgt ggtcaccaac
    13861 gtcaccaact tcggcgcctt tgtggacatc ggcgtgcatc aggacggcct ggtgcacatc
    13921 tccgcgctgt cgaacacctt cgtcaaggac ccgcacagcg tggtcaaggc gggccaggtg
    13981 gtgaaggtga aggtgctgga ggtggacctc ccgcgtcacc gcatcgcgct caccatgcgc
    14041 ctgggcgacg aggtggcggc gaaacgcggc ggggccgggg caggacgcga cgagggcgcg
    14101 ccgcgccgcg gggaaggcgg cccggcgccg cgtggcgagc agcgcccgcg cggctccgac
    14161 cctcgccgct cgcccgcgca aggcaagggt ggcgcgcgcc aggagccctc ccgcccggcc
    14221 gccggcaacg cgctcgccga agccttcgcg cgcgcccgcg gcaacaagtg aggagccgga
    14281 catgcccacg acgatccacg gcatcaagaa ctgcgacacg atgaagaaga ccttcgcctg
    14341 gttcgaaggc gcgggggtcg cctatcggtt ccacgactac aagaaggccg ggatcgacgc
    14401 cgccacgttg gcgcgctggt gcgagcgcct gggctgggag gcgctggtga acaagcgcgg
    14461 caccacctgg cgcaagctcg cgcccgaaca gcaggcgatc gccgacaccg ccgccgcggt
    14521 cgcgctgatg caggcccagc ccagcctgat ccgacgcccc gtggtcgagt tcgccgacgg
    14581 cgagctcgtc gtcggcctgg acaccgaggc cttcgagcgc cattgccatg gctgagccgc
    14641 tacggccagc aagaaaaccg gacaccccga catgaacaag cccctcccca ccagctacgt
    14701 gcaacgcttc ctgctcgaag atctcgacat ccgcggcgcg gtcgtgcgcc tcaccgacgt
    14761 ctgggaggcc atgcaggacg ggcgcggcta tgcgcccgcg gtggcgcacc tgctcggcga
    14821 gatgagcgcg gtgtcgaccg tgatcgccgg caacctcaag cagcccggcc ggctgacctt
    14881 ccagatcacc ggccacggcc cggttagcct gctggtcatc gactgtgccg agacgctcaa
    14941 cctgcgcggc tacgccaagg ccgagggcac gcccgccgcc ggcacgctcg ccgagctcgt
    15001 cggcgacggc cgcctgcagc tctcgctcga catcgagggc ctcgaccagc cctaccagag
    15061 cctggtgccg ctcgagggcg acagtatcgc cgaggtcttc gagcactatc tcgcccagtc
    15121 cgagcagcag cccgccaggc tgtggctggc gggcagcgcg caggcggcgg tggccctctt
    15181 cgtgcagaag ctgcccggcg ccgacgccaa ggacctcgac ggctggtcgc gcgtgcagca
    15241 gctcgccaac acggtgcgcg aggacgagct gctcggcctc gacgcggagg cgctcctgcg
    15301 ccgcctgttc gccgaggaga acgtccgcct cttcgaggcg cgtcgggtca cccacgactg
    15361 gcccgccgat ccggagaaga tcgccgagat gctgcgcgcg ctcggcgagg acgaggtgcg
    15421 cgcggtgctc gaggaacacg gcgaggtggt ggtgcacgac gacctttcca accacaccta
    15481 ccgcttcgac cgcggcgacg tagacgccct cttccgcccg cccaccctgc attgagcgaa
    15541 aatgccggcg atgcaggcgg gtttgcgccc ccggccttgc ccgaacgtct tcgcctaagt
    15601 acactcgccc gattttgaag accgttccgc acatgtccgc cagcgcgccc gcaagatcga
    15661 tcgagttcca caacacgacc ctgggcgcca ccgtcgccgt cctgcaggcc gcggaaccga
    15721 ccacgctcgc cgattcgctg cacaagatgc tcggcggcat gcccgatttc ttcaacggcg
    15781 aggccgtcat tctcgacttc gcgggcgtcg cgcagatgcc cgcgcgcgtc gactggtccg
    15841 gcctgcagtc cttgctgcgc cgctatcggc tgcagccgat cggggtgatg cgcgtgccgg
    15901 ccgaacacca cgagggcgcc cgtcgcgccg gcctggcgct gatcgaccct tcgcagctcg
    15961 ccggccgccc gcccgccgag gcgcccgtgc agccgacgcc gagggcggaa cccgccgcgg
    16021 agccggtacc cgccccggcc gctacgacca ccaccccggc catgttcgtt gaccgcccgc
    16081 tgcgctccgg ccagcaggtc tacgcgcgcg gcaccgatct cgtcctgctc ggcggcgtca
    16141 gccccggcgc cgaggtcatt gccgacggca gcatccactg ctacggaccg ctgcgcgggc
    16201 gcgccatcgc cggcgcccag ggcgaccatg gggcacggat cctggcaagc aacttcggcc
    16261 ccgaactggt ctcgatcgcc ggcgtgtacc gcaccttcga gcgcggcatt ccggaggcct
    16321 tcgcgggcaa ggcgaccctg gtgcggctga ccggcgccga ccatacactc aacctcgaag
    16381 cgctgaagct cgactgagcc agccataccg catccacaag gggaaaccgt gagagtcatc
    16441 gtagtcactt cgggcaaggg cggcgtcggc aagaccacca ccagtgcggc attcgcctcc
    16501 ggactcgccc tgcgcggctt caagaccgct gtcatcgact tcgacgtcgg cctgcgcaac
    16561 ctcgacctca tcatgggctg cgagcgccgc gtcgtgtacg acctggtcaa cgtcgtcaat
    16621 ggcgaagcac gtctgaacca ggcgctgatc aaggacaagc actgcgacaa cctgttcatc
    16681 cttcccgcct cgcagacgcg cgacaaggac gcgctgaccg aggacggggt gggcaaggtg
    16741 ctcgaggaac tcgagcacat gggcttcgag tacgtggtgt gcgattcccc cgccggcatc
    16801 gagcgcggtg cggtgatggc gctgaccttc gccgacgagg cgatcgtcac caccaacccc
    16861 gaggtctcgt cggtgcgcga ctccgaccgc atcctcggca tcctgcagag caagtccaag
    16921 cgcgcccgcg acggcggcga gccggtcaag gagcacctgc tcatcacccg ctactcgccc
    16981 aagcgcgtgg aagacggcga gatgctgtcc tacaaggacg tccaggagct gctgcgcgtg
    17041 ccgctgatcg gcgtgatccc cgagtccgaa tcggtactgc acgcctccaa ccagggcacg
    17101 ccggcgatcc acctcaaggg caccgatgtc gccgaagcgt acgccgacgt cgtcggtcgc
    17161 ttcctcggcg aagacctgcc gctgcgctac gtcaattacg aaaagcccgg cctgatcaag
    17221 cgcctgttcg gaggcaagtg acatgtcctt cctcgcccgc ctcttcggcg aaaagaagaa
    17281 gaccgcggag atcgccaaga accgcctctc gctgctgatc gcccacgagc gggcaggcgg
    17341 gagcccgacg gcggacttcc tgcccgcgct gcagcgcgag ctgatcgagg tgatctcgaa
    17401 gtacgtcgcg gtcaatccgg acgacatcaa ggtgcacctc gacaagcagg acaacatgga
    17461 agtgctcgag gtcaacatcg tgctgccgga gcagaaccgc tgaggcgcgc tcgcccgggt
    17521 gatgaaatcg gtaaccatag cggacttaaa atccgccggc gcaagcctta cgggttcgag
    17581 tcccgtcccg ggcaccatga cgctcagccg ctgtcccacc cttgccttgg cgcaccgccg
    17641 ggcaagccga ccggacaggg aaagcaatga tcgttctcga cctccactgc agcaacgaac
    17701 accgcttcga gggctggttc ggctccgccg cggccttcga ggagcaactc gcgcgcgcgc
    17761 gggtgagctg cccggtgtgc gggagtaccg cgatccgccg cctgcctagc gccccctacg
    17821 tgcagaccgg ccaggccgcg actgaagcgt cgcctgccgc gcgcgccgtc caggcggtca
    17881 atgccgcccc gccctccgct ccgcctcccg aggccctcgc acgcctgatg acgcagctgc
    17941 gcggcatggc acgcgctgcc gaggacgtcg gcgagcgcct gcccgaagag gcgcgccgca
    18001 tccactatgg cgagaccgag gcgcgcgaca tccgcggctc ggcctccgcc gacgaggtgg
    18061 agtcgctgct cgaagaaggc atcctggtgc tgccggtgcc gccggccgag gaagacctgc
    18121 actgacgacg cctgccgcgt cgcagacagg gatgcgggcc gatcacggcc tccgcctctc
    18181 ccagcctttc tcgagcgcag gcctcgcgat tgcccgcgtt caggtctgcg ccaggatcag
    18241 cggcacgcgc atctcgtctg cactcagccc gccatgcacg ccgatcatgg cgtgctcgtg
    18301 ctctccgggc acatgatcca cgatcgtcca cccggcctcc atcagcagca catggctccc
    18361 caggcgctcc gccaggcgcg gatgcggcag cccgggcccc agcaggccgg cggcgagaaa
    18421 ctccccgctg cgcactgcga cacccttgcc ccgtagctcg cccgccgccc aggcctcgaa
    18481 ctccccctcc gcacccgcgc gcacgcggca gaaggccagc cggcgttcgc cgaacagcgg
    18541 cgcggcgagc atggcggcga cctcgccatc gggtgcgagg tcgatgcgac gctcgggggg
    18601 cgcatcgatg aagccatggt cggccgtgac cagcaggcgc acgtcccgcc ccgccagtgc
    18661 ctgctgcagc tgcacgaagg cggcatccag ccgcgtgaag caggcgatcg cctccggcga
    18721 gcgacagccg tgctcatggc tcagcagatc gaacaccgga tagtaggcgt ggatcaagcc
    18781 cccgctgtgg gcgagcgcat ccgccatgtc gacgatggcg gcgacgcagt cgtccagccc
    18841 gtcgtaggcc tcgatgtgcg ccccacgccc gtggtgcagc gagaagcgcg agaaggcgat
    18901 gtgcgccggc gagaccaggg tgaccggtcg gcaggcatgg cgatacatcg gcgcgaccgg
    18961 gaacaggcgc ggcaacaggc ggaaggcctc cagcggctcg ccactgcgcc ggacgagcgg
    19021 caagggggca atcacgccgc cgaagcggcg gtcatgaatg aaccagccat tgagcccgtg
    19081 ctcggcgggc gcaacgcccg tcgcgagcgt ggtgatcgcg ctcgccgtgg tgctcgggca
    19141 caccgagctc aggctcccgc gcctggcttt ctgcagcgcc gagccatgtc cgagtgtgtc
    19201 gagaaagcgc tcccccagtc cgtcgatgag cagcagcacg acgagcgcgc gctcgcccgg
    19261 cgcgatctcg gccgcaggcc agtcggccct gcggtcgtgc agccaatggc gcaggccgcg
    19321 cgcgaagccg aagagcccgc cctcgccata atcggggagt acggcgccgg ccgggagggg
    19381 gaagccagga tcgatgctga aggccatgtg gtgcgcgagg atcgcggatc ggcaggagaa
    19441 ggttcgagcc taccccgcaa ggcttcgtcc ggcaaagcac tggaggctgc tgcggtggac
    19501 cagggcctga aagcaaaaac cggatgggcg gcgagcgcac atccggttct taaatttgga
    19561 gcgggaaacg agtctcgaac tcgcgacctc aaccttggca aggttgcgct ctaccaactg
    19621 agctattccc gctttatcga aagcggcgca aattatagct acgtttgcac cgcttcgcaa
    19681 tacttcttta caactttttt actactggag gcgcgactcg gaatcgaacc ggggtacacg
    19741 gctttgcagg ccgctgcata accactctgc catcgcgcca cgaccgtttc ggccggtcac
    19801 cccaagactt cggggccacc tgctcgggca ctgcccaagc tgcgaattct ttggagcggg
    19861 aaacgagtct cgaactcgcg acctcaacct tggcaaggtt gcgctctacc aactgagcta
    19921 ttcccgctcg ggaaagaccg ccattatagg cagtattttc tgttcgtcaa cctcaatctg
    19981 tattttctcg cgctgcgctt cacttttccg tatcgcgcag cagcggcatc gcgcgccgca
    20041 gatagtaccc catcgaccac agcgtgagcg ctgcggccac gtagatcagc acctcgcccg
    20101 ccaggctcag gtcgacgccg tacagcgacg cattgaagag cagcatcggg atcgcgacca
    20161 tctgcgcggt ggtcttgagc ttgccgacgt aggccacggc gacgctcgcc gactgcccga
    20221 cccgcgccat ccactcgcgc agggccgaga tggtgatctc gcgcccgatg atgaccaccg
    20281 caatcagcgc atccacccgc ccgagctgca ccagcaggat caaggcggcg gccaccatca
    20341 gcttgtcggc gaccgggtcg aggaaggcac cgaaggcaga ggtctggccg agtgcgcggg
    20401 cgaggtagcc gtcgaaccag tccgtcaccg cggcagcgac gaaaatcacc gtggcgacga
    20461 ggttctgggt cgcgatcggc atccacgatt cgggaaggta gaagaggccg acgaagaccg
    20521 ggatcatcgc gatccgcgcc caggtcagcg cattcggaat gttgagcggc atgccggagg
    20581 gcgactcgca tggattgggg gagcgccgag tatatcaagc gcccgccccc ccggaggggc
    20641 ggctgcattc cgtgcgagag ggcgatgtgc cgaaagtccc gcgccgcggt gctttcggta
    20701 cacacaggcg ggtgcgcgct aggtaagatc ttcggcaagc gttcatcttc ctcgcatcgg
    20761 ccgtcccggt cccctccaat gcctgcccct tcctccctcg ctgcctggca atcgctcgag
    20821 cagcgccgcc tccatcccct gccctccctt cgcgatcgct tcgccgccga tccctcgcgc
    20881 gccgcgcgca tgcaggtcgg cgcctgcggc atgaccctgg attactcgaa gaacctgctc
    20941 gacgaacacg agctcgcgct gctgctgcgc ctggccgagg aggccggcgt cgccggtcgc
    21001 atccgcgcga tgttcgacgg cgaacgcatc aacaccaccg aggcccgcgc cgtgcttcat
    21061 gtggcgctgc gctgcccgcc gggcacgcgc tggcaggccg gaggttccga cgtcgccgcc
    21121 gatgtgcatg cggtacgggc acgcatgcgc gccttcagcc tgcaggtgcg cagcggtgag
    21181 tggcggggcc atggcggaga acgcatcacc gacgtggtga acatcggcat cggcggctcg
    21241 gacctcggcc cggcgatggt ctgcgaggcg cttgccgacc acgccggcga cggcccgcgc
    21301 atgcacttcg tctccaacgt ggacggcgtt cacatcggcg acgtgacgcg gcgctgcgat
    21361 ccgcgcagca ccctgttcgt ggtcgcctcg aagaccttca ccacccagga gacgctcgcc
    21421 aacgcgaacg tggcgcgtgc ctggatcgtc gccgcgcacg gcgacgaggc cgcggtcgcg
    21481 cgccacttcg tcgccgtgtc gaccaacgcc gcagcggtgc gcgacttcgg catcgacacc
    21541 gccaacatgt tcggcttctg ggactgggtg ggtggacgct tctcgctgtg gagtgcgatc
    21601 ggcctgccca tcgcgctcgc gctgggcccc gatcgcttcg acgaactgct cgccggcgcg
    21661 cacgcgatgg acacgcattt ccgcgctgcc ccgcctgcgg ccaacctgcc ggtgctgatg
    21721 gcgctgctcg gcatctggaa cgtgaatttc ctcggcgccg cgagccagct catcgccccc
    21781 tatcaccagc gcctgcaccg cctgcccgcc tacctgcagc agctcgacat ggagtccaac
    21841 ggcaagtcgg tgcgccacga tggcgtagcg gtggattgcc gcaccagccc catcctgtgg
    21901 ggcgagcaag gcatcaacgg ccagcacgcg tatttccagc tggtgcatca aggcacgcag
    21961 ctcgtgccgg tggatttcat cggcgtgctc gacgccgggc gcgaggacga gggcctgcac
    22021 cgcatcgcct tcgccaacct ggtcgcgcag gccgaggccc tgatgcgcgg caagaccgct
    22081 gccgaggccg aggccgagat gcgcgccgcc ggcctccccg aggatcgcat cgccgccctg
    22141 ctcccgcacc gcgtgttccc aggcaaccgg ccgagcaacg tgctgctgct cgatcggctc
    22201 gatcccttca cgctcggcgc cttgatcgct gcctacgagc accgcacctt cgtccagggc
    22261 gtgatctggg acgtgaacag cttcgaccag tggggtgtgg agctcggcaa gcagctcgcc
    22321 gcacgtgtgc tcgccgagct cgacccgcgg gcggtctccc cctcggagcg cgcgcacgac
    22381 gccagcacgc ggggattgat cgagcgttat cgcgcccacc cgcgctgagg ggaccctgga
    22441 ggcgcgccgg caggtgcgaa tcgatctggc ggcatttgca cgatgcctgt cggcgagcgc
    22501 aatgggcgga ggaagagcgc gggcataaga tgcaagcctt ccttcaccac ccggagccac
    22561 cagcatgctc gccttccagg actattaccc cgaaaacgtc gcccattgct acggctgcgg
    22621 ccgcctcaac gaacacggcc accagatcaa gaccttctgg gagggggacg agaccgtcac
    22681 ccgttaccac cccaggcccg agcacacggc gattcccggc ttcgtctatg gcggcctgat
    22741 cgcctcgctg atcgactgcc acagcaccgg caccgcagcc gctgccgcct atcgcgccga
    22801 gaaccgcccg atggacagcg agccgccctt gcgcttcgtg accggctcgc tgcacgtcga
    22861 cttcctcaag cccacgccga tggggccgga gctcgtgctg cgcggccgtg tcaaggagat
    22921 caagggccgc aaggtcgtcg tcgaggccga agtgtgggcc ggcgaggtga tgacggcacg
    22981 cggcgaggtc gtcgcagtgc agatgccgga caccttcaag gcctgatgca gccgcggggg
    23041 cgatggcacg gatcttgatt gaggaggatg gcattccctc aactttttcc gcaggcagat
    23101 catgaaaatc gccgtctcca gccagaactt ccgcaccgtc acctcccacg ccggcaaggc
    23161 ccggcgcttc atcgtcttcg acctcgccac cccgtgcacg ccacgcgagg tcgagcgcct
    23221 cgaccttccg cgcgagttcg ccctgcacga gtaccgcggc ctcgaccacc cgctttttgc
    23281 gatggacgcc gtaatcaccg gcagcgccgg cgatggcttc gtgcgccggc tcggcgcacg
    23341 cggcatcgag gtggtcctga ccggcgagac cgacccgctg caggcggtac gcgactacgt
    23401 tgccggcgtc gtgaagcctc cgctgccgca cgaacacgac catgggcacg cccatgccca
    23461 tgcgcacggc catgctcacg acgaggcact ctgaacgtac ccgaactgcc acttgcgcta
    23521 ggtctcctgc cagtctggcg caatcggcag ggcatcaggc aggcaatgca ggccgcctcg
    23581 cccacaaaat cgcgccttcc agggctattc cggcgctttc gatgctggca cgattcctgt
    23641 tagggatgag gagacgaggc gcccacctca tccgccaggc atccgggtgg cgcgccaccg
    23701 ccagccggat catgcacctc ggggcacggc ctcgctgtac ccatcctcca tccgacccag
    23761 gagtgttcca tgcagaacaa gctgctcgcc gacaagtatc cgatccacgt gctcgagctg
    23821 ggcaagaacg agaccgcgca tgagcatctc gacgatctgc tcaaggcgat cgaggcccga
    23881 gccgaggccg atcccaccgt gcgcctgatc gcgaccttcg accacctcag ccacacgcag
    23941 ctgatcggcg gcgagattcg ccccgacatc ctcgcggcca agaacctgat cttctgcttc
    24001 ggcgtgaagc tgctcgaccc cacgatgatg gcggtgcgtc cgcgctcgat cggcttcgcc
    24061 gagttgcccg accgctttgt gatcagcttc ctggaagcac cgatgcccga ggccaaccgc
    24121 aagatgatcg agtgggtcac cgccctgcgc aaggccgcct gaagaccgaa cccgcccgcg
    24181 cgtgcgggcg cgtgccgcca tgtacttcca tcccctgcac agccccgact ccagcctcat
    24241 cggctacctg ctcgccgacc tcgacgagca ggaggcggtc gtcatcgacc cgccgccccg
    24301 ccagaccgag ctcatcctgg ccctcctcac cgagcgcagc ctgcgcctgt gccacgtgct
    24361 gcgcacccat gtccatcggg tggacgcggc cgactgcagc gcgctgtgcg actgcacgag
    24421 cgcccagctg gtggtcggcg aggcggcggc actgccgcag ggctgcagtc gcgaagcggt
    24481 gcgcgtcgcg cacggcacgc gcctggtgtt cggcaacgag gtcgtgcgcg tgctgagcac
    24541 gccgggccac acgcccggct gcctgagcta cctgtggcgc gaccggctct tctgcggcga
    24601 cgccttcgac gtgggcagct gctgcgccgg cgacggcgag gccgatccgg gggcgctctt
    24661 cgacacgctc acccggcgcc tgttcacgct gccggagcag acgctcgtct tccccgctca
    24721 tccgatcaag ggccgccacg tggccacgct cggcgagttg cgcgcgcgtt acgcgccgcg
    24781 cctgcagcag agccgtgacg gcttcatcac cgacatgatg cagcgccgcc cgcgggcgac
    24841 cacgccgcgc atcgctgccc cggccgctgg cagctgaatc aggcttcgcc gagcgcctcc
    24901 gccgcgatcg gccgaccacc ctcgacgtac gcggcgaact cgtcggcaag ccgtgcgctt
    24961 tccgcgatcg ctcgccgcca caccgcggca cgcccggcgt ggtcggcccc ataggccttg
    25021 aagtcgcgcc ggtcgggcag cttggcgttg ggcaggcgcg caatccagtc cgcggtcgga
    25081 accagcagca ccacgttgtc cagccgcgcg gtggcgcgat ggcgtgatcg cagcgacttg
    25141 tccagccagc cgggaacgac gctggcctgg aaatgcgggt agagcacgag ccgcgggcgt
    25201 tcgcaaagcg tgtcttccga cgcccgcatc gaagtcccct cctgcccacg tcctcccccc
    25261 ggcagtgcct cccccgcatc gcgcaacatc gaagcgtaat ccagatgcag atggtagtcc
    25321 gtgatgcccc cgtcccagta ggcaccgggc ggcgcgccgg agatgtcgtg cacggcctgc
    25381 agccagaacg ggatcgagca gctcgccacc agcgcctcga aggcattgtg cgggccgagc
    25441 acgcacgtgc gcccggcgta gtcgtccatg gcgaagggca gcgcttcgcg cgcatcggag
    25501 aacaccacgc gctccagcca ttcgcccatg cgcgcgcgcc cgcgcaggtt ggccgcgtag
    25561 gcgcccgcgt agccgacgag cgtacgcagc cgcccctcgc gccgcagcag gggatgcacg
    25621 ccgcggctgg tgaagaggtg caggcgaaag cgcgggtggc gcagcagctc gtcgctgcgt
    25681 ccgcccagat gactggcgag acgcgcgcgg aaggcacggc tgaccgcggc ggcgccgggc
    25741 tggcgcaccg ggcggccact tgcacgcgcc tgcgcgagcg cttcggcgtc gagatagctc
    25801 tcctcgacgt aatggcgcgc catctcggca agcgccgtgt cggcatcggg caggcaggcg
    25861 ctggccatgc gccaggcgcc gatcgaggcg ccgagcaggt ggaccggcgc accctcgccc
    25921 gccagccaat ggccgaagag gaagcgatcg agcggattca ggatgagccc cttcggcccg
    25981 cccgcggcgc cgggcacggc gagcacgtcc gcgggtgtca ggccgcgttc gcgcagctgc
    26041 gcgcgtgcga ccgggccggc gaggatgcgc agcgcgggct tcatcgcggc gacgatgccg
    26101 gtgccgcgat cacggcttga tcggctccca acccgggtgg tcgtactcgc ggccatagaa
    26161 gttcagcgtc tcggcgaccc gcagcaagcc gagccgcttg gcctgcaggc gcggcgcatc
    26221 gcgcatcagt ccggcgccgt cggagatgtc accgagcagc cactgcaggt ggcgacccgg
    26281 ccggccttgg aagtcccgcc cctcgccgat tgcggcgacc tgagcgagga tctcggcggc
    26341 gagcgcgacg tgcgcggcct cgtccatggc cggatcggac acccgcgcag cgaccatcgc
    26401 acgcagctgc agcatgccgg cgcgcagcct gtcgtcggcg gggcgcggca gctcgtctgc
    26461 gggcgcctgc agcttgggtt gcgggcgcgc gtcgtcggcg gcgaggatgg gcgcgggggc
    26521 ggcacacagc gccgcgacgg cggcgcacag gaaggcgagg cgcatgcacg atctccggtt
    26581 ggatgcgaac ggtcgccatc ctacccgggc gcgccccgaa agcgcttgaa ctgaatcaag
    26641 cgaggccccc cgcccctgcg tcgcttccct ggctaggtag ccgatccggc ctcctcgacc
    26701 gtcaccgtca cgcgctggcc tggcgcatcg gcatacagca cgggccgatc gggcgcgggg
    26761 tctgcgacgt gcaccaccgc gctccagtcc gcgtcctccg gcaacagctc gccgagccgg
    26821 ttcggccagc gcaggatccc tgcctcgtcg agcgcattgc ccgccatttt cgggaacagc
    26881 gcgaagtaca gcaggtcggc ctcgatcagc tcgttgagga agtgggtgcc gagcgagacg
    26941 tcgggcacca ggtgttcgtg catggcgacg atctcgcaca gcgcggcgac gtgattgatc
    27001 tcggagaaca gcaccgggat gccgaggaag ggatccttcg aaccccagcg tccggggccg
    27061 agcatcagca cgcagcgtcc gccggcgagc gcgttgaggc gaccgagcac gcgcgtcacc
    27121 gcgaggcgcc ggggttgatc gagcgcggcg aaggcggccg ggcgcaccag cacgatgcgc
    27181 tcggggcgga tcacccggct cggcccgatg accgcaccgc gcgcctccag caggcgcgcc
    27241 acgccggccg gcggctccac accctgcacg ccctccacgc tgcgcacctg catcggccgg
    27301 cactgcagca ggttgatgcg atagccgccg tcggggacga agttgagcgc gaactcgatt
    27361 tccaccggat gcgcgtaggc tgcgtgcagc gtgcgcagca gcgtgcgcag gtcggcgacg
    27421 aagtccgtgg acgcgatcag tccgtcgaag gtcaggaagg ccgggcggtc ctcggcctcg
    27481 cgcgtcgtga acagcgcgtg cggaaaatcc gcatggccgc gcaccagctc ggcgaacggt
    27541 cccgagacta cctcgccgcg ctccaggtcc aggctgtcca tgcggcgctg ggcgtggcgt
    27601 gcgatcgcgc cgaagctggt ctcggggcgc agctcgggcg cgtcgagggc gatcaggcga
    27661 gtgtagtcgt cgtcggcgcg atcgaccgcg cgcgtgccca ggccggccac caggcgcacc
    27721 acgcccgcct tcatgtcgat gcgcgggttc cacggatacg gattcaccga caggccgacg
    27781 ccggccgcgt gcggattgaa ccagcgcccg ccggcggtgc ccgagacgcg catgatcagc
    27841 agcgccatct gctcatgctc gtcgagcagg ccgcggcgct cgcggtagcg cagcgccgac
    27901 tccgacagcg tgctcgcata cacctggcgc accgcgtcga gcagcgcagc caggcgctcc
    27961 tcgcgcgtgc cgcggttggc gcagaagaca ctgtcgtact ggccggcgaa cgcgttgccg
    28021 tagcgatcct ccaggcgcga gctcgagcgc acgatgaagg gccactcgcc gaagtaatcc
    28081 agcatgccct cgaactggcg cagggtggac tccgggaagc ggccgcgcag gatgcgtgca
    28141 cgcgcgccgt cctcgccgtc gagcccctgc aggaagccct cggcctcgcg ctggcggcgg
    28201 cgcacccacc acaacccgtt gatgacgaag aaggtgtcga acacctcgct gccgacgtgg
    28261 aaggagtcgt gcgcctcgag gcgggcgtgc agcgcgggcg cgtcactgcg cacgatcgcg
    28321 cgcgcgatca acatgccggc cgccttgccg ccgatggtgc cgatgccgat catgcgcgta
    28381 cgcaccgcga gcaggtcgtc cacattcagg tagcgcgcga tcagctcctg caggcccgcc
    28441 tcgtcgggaa acagcaggcg cgccaggcgg gcgaaggcgg ccgcctcgcc ggcgaggtcg
    28501 ggcgcctcgg ccgcgcgcag ggcggcgaag gtgcgcgcct ggtcgaagag ctgttgccag
    28561 cggctgcgga tctgttcgtc ctccagcccc ggccagcccg atccggcgag gatctcggcc
    28621 accgtgccgc tgtcggccac ggcgcggaaa cgatcgcccg gctcccaggc gtggatcagg
    28681 ttcatcgccg cggccgagcg gtgctgcacc ttgatcggcc ggatgtagag ccggtcgcgg
    28741 cagcggaaca catcgagcag gtactgcgtc gtctcggtga tcatgtccat gcccgcgcgc
    28801 gcatgccgat gacgcagcac gccgaagtag gtcaccgtgt cgaggtcgaa gagccgcggg
    28861 caggtcagtc ggaagaagtt gccgagcatg cggtccgaaa gccaggcctc ggcgagatcc
    28921 gacaggcagt cgaagacgta catggtctcg cggccggcgg cctcgatcac cgaatgcacc
    28981 tggtcgacga aggcgtcgaa gccgtcctcg gggcgcgggg tgaacacctc ggccccgctg
    29041 tcatccccga gcagcggcgg atgcgcggcg aagcggaaat agatcagccg ccgcccctgc
    29101 gcgcgcgccg cccgcgcata gggcagcacg agtgcgcgat agtcgtccag cgcctgcacc
    29161 tgccagacga tgttgtcgcc gcgcgccacg ccgcggagca ccgcgtccag gccgggcagg
    29221 ccagtggtgg gggcgaaggc ggatggcgtg ggcggaacgg tggactgcgg aacgggggaa
    29281 atcatgggag ctacctcgca caaggcctgc gagcgcgatt atgcgcgcaa ggcgggcggg
    29341 aactttttcg cagcgcggca ttctctccgc acgatcagcc catcaggcca cccggtccgg
    29401 cacaatcggc agcctgcctc gcccgcccgg ttgggtcggc ggcggttcga ccgcagtcat
    29461 cgcggccggg tactgtcccg tcccgtaccg tccctgcgcc ctgacgcctc actcctcacg
    29521 cccccgcccc tcacgctccg atgccccgaa cgaacgcagc ccgcaccctc ctcctcgcct
    29581 tgcccgcagc cttgctgctc gcctgctcct cggagccgcc agacacccat ccggacaagc
    29641 cggtgaccca gcgccgcgag gccttcaagg cgatgctgcg cagcaccgag cccatgggca
    29701 ccatgttgaa ggaccgccgt ttcgacgccg accgcttcgc cagcctcgcc gaccagctcg
    29761 ccgcggcgcg cgaaacgccc tggaagcact tcggcgcgga cacgaattac ccgcccacca
    29821 aggcccgccc tgcggtgtgg gagaagcccg acgagttcga gcgccgacgc agcgaattca
    29881 tcagcgccac cgaccgcctc ctcgctgccg ccgcggcgcg ctcggaggat caggcgcgca
    29941 gcgcgctggc cgctgtgcag gacagctgca aggcctgcca caaggatttc cggcgctgac
    30001 cgcgcgccat cagggcgggc ggagaggctg tagggagggc gtgtgcctcc ctacatcaca
    30061 tgtcctcgaa caagcaaagt cctcgaacgc cgccttcgcg cctgccggcg ctcctacatg
    30121 caccagcgcg ctccgcggcc gatggagata cggtggcggc tgaaaggacg gccgtgcagc
    30181 gagcgaggcg tcctacgggc gatcgtccag gggttccgag gctgcctcgt gcaggcggcc
    30241 ctgccagctg tcgcggcggg cgagctcggc gctgagccgg ggggcgagtt cggagaggcg
    30301 gatgttccac tgcggggcca gcttgagcgc gggaggcact tcgctgccga gacgctggag
    30361 caggatcgtg ggcgacagcc gctccacgaa gtccgcgagc agtgccatgt actcgtcttc
    30421 ggccagcagt ggcacgctcg ccggatcgcg ctcccagtcg cgtgccatcg cggtgccccg
    30481 caccagctgc agctggtgca gcttgagcgc cgtgatcggc agcgcggaca ggcggcctgc
    30541 ggcctcgagc atgccggccc gcgtctcgcc gggcagtccg aggatcaggt gggcggtcac
    30601 cccgaggcca cgtgccgcgg cgcgccggat cgcgtgctcg ctgcaggcaa agtcgtggcc
    30661 gcggttgatc ctgcgcagca cctcgtcgtc gcaggattcg acgccgatct cgagctcgac
    30721 gatgtgttcg cgcgcgagct cggccaggta gtcgagcact gcgtcgggca ggcagtccgg
    30781 ccgggtgccg atcgccagcc cactgacgcg cggatgggcc agcgcagtct cgtagatctc
    30841 gcgcaggcgc gcgaactcgc cgtaggtgtt gctgtaggtc tggaagtagg cgatgaagcg
    30901 ctgggtgccc ggatagcgcc ggtcgagaaa gcgcaggccg gcgtcgatct gctcgccgat
    30961 cgggtcgcgg cgatccaggt agccgggggt gaagccggcg ttgttgcaga aggtgcagcc
    31021 gccgctgccc acggtgccgt cgcggttcgg gcaggtgaag ccggcggcca ccgagacctt
    31081 ctggacccgc ccgccccagc gccgcttcac atggtcgttc caggcgttgt agcggcgctc
    31141 gccgaagggt gaggctgcgg ccctcgcggt gccgtcggag tcggggatgg ggtcggaatg
    31201 cagcgcggaa acgaatgtgg gcgcggagct catgcaaaag gccggggaga tggacgaagc
    31261 aggcgacggt ggcgggcgcg gtcggaaacc acacccgggc gcgagtgtgc cgccgaccac
    31321 cgattcagcc cttgatggtg cgcaagcgca gccgcattgg cgcctgccgg cgctcctgca
    31381 gaagccgtcg cggcgacgat gggtgtgtag gagcggcggc agccgcgaag acggcggtgt
    31441 cacgggcgac aggggcttgc ccagcctgca tcgcccattg gcgcctgccg gcgctcctgc
    31501 agaagccgtc gcggcgacga tgggtgtgta nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    31561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    31621 nnnnnnnnnn ggagcggcgg cagccgcgaa gacggcggtg acacgggcga caggggcttg
    31681 cccagcctgc atcgcccatt cgcgcctgcc ggcgctccta cagaagccgg cgcggcgacg
    31741 atgggtgtgt aggaggaacc gagcgggcgg gctcaggcgg tgccgtggtc gtcctcgccg
    31801 atcagcacca gaccgtcgga gagccacttg tgcggcggga tctccaggtt ggtcggagcc
    31861 ggctggctca gatacacccg gccggcgaga tcgaagatcg agccgtggca ggggcacagg
    31921 aagccacccg gccaatccgc ggtcatgccc tcggtggtgc cggtagcgaa tttctcggac
    31981 ggcgagcagc ccagatgcgt gcagatgccg atcacgatca ggtattcggg cttgatcgag
    32041 cggtgccgat tggtggcgta gtcaggctgc tgcggctcgc ccgaacccgg gtcggccaga
    32101 cgggcctcgt tctgctcgag cgtcgcgagc atctcgggcg tgcggcgcag gatccacacg
    32161 ggcttgccgc gccactcgac ggtcatcatg tcgccgacgg cgagcttgga gacgtcggcc
    32221 tcgacgggtg cccccgcggc gcgggcacga tcggagggcg taaggctggc gacgaaggga
    32281 attgcagtgg ctccggcggc gaccgcaccg gcagcgctgg tggcgatcag cagcttgcga
    32341 cgttgggcgg caagctcgga tggcgtatcg gacatggcag gcctctcccg ggagtgagtt
    32401 caggtttccg gcccgcacgg gcggcggaaa aaagggcgaa gcggccgggg ggcactcaat
    32461 cgaaactacg ctgccagggg caagaccgtt gaggggggac gatcatgcag cgatcacgac
    32521 gcggcctgct tcgctcgggt ttctattaag caacagccgt gccaggtttg aaaaagtgcg
    32581 cttcgacgct cgattcggcc tcgctggaag cgttttgacc tgccaaagac tgccgatgac
    32641 gcagcttcgc tgccaatcct ggcagtcaag tagatgcggc ccttcccgca gcgccagccc
    32701 gagcgcctgc tcaactgccc tgcgggctct ttttttcgtc cccctccccg ccctcgccct
    32761 ccagcaagcc gagcgccttg agccttcgat acagcgtgcg ctcgctgatc cccagccggc
    32821 gtgccagctc gcgccggctg ccacgatgcg cgcgcaccgc gcgcaacatg gcctggcgct
    32881 gcacctcctc gagatccagc ggatcgcgca ccggcacagc ggcggccggc ggacctccac
    32941 tggcaaatcg tgacccggca ctctcgcgct cgggatgcaa cacctcctcg ggcaggtgct
    33001 cggggccgat cacctcgccg tcgcacatca ggctggcgcg ctcgagcacg ttgcgcagtt
    33061 cgcgcacgtt gcccgggaat gggtaatcgc acagcacgcg cagcgcggcc gggcccagcg
    33121 acagcgtgcg cttgggcgcg acgcgctcga gcagggaatc gatcagcaag ggcaggtcgc
    33181 cctcgcgctc gcgcagcggc ggcacggtga tcgggaaggt gttgatgcgg aagtacaggt
    33241 cctggcgaaa gccgccctcg gcgatcatgc gcttgagcgg gcggtgggtg gccgagacca
    33301 ggcggatgtc ggcgcggcgc agctcggtgg agccgacgcg ccggtaggtg ccggtctcga
    33361 gtaggcgcag cagcttgacc tgcatgccga gcgggatgtc gccgacctcg tcgaggaaca
    33421 gcgtgccgcc gctggccgcc tcgaccaggc cgggcttgcg cgccgtggcg ccggtgaagg
    33481 cgccgcgctc gtggccgaag acctcgctct cgaacagggt ctcgggcagg ccggagcagt
    33541 cgaccaccac gaacggaccc tcggcgcgcc ggctggcctc gtgcaccgcg ctcgcgagca
    33601 gctccttgcc tgtacccgac tcgccctgca gcaaaacgct cgcgtccgag ggcgccaccc
    33661 gcgcgatcag ctcgagcatg cgctggaagg cgggcgagcg cccgatcagg ccgcggtggt
    33721 ccgacacccc gcgggcgacg tgcatcggct ccatcttctc gatgaaccag gcgatctcgc
    33781 cgctggcgtc gcgcaccggg gagagctcga tgttcacgta ttcctcgccg cgcggcgtgt
    33841 ggtgcaggtg cagcacgcgc tcgcgctggc cggactgcag gctgcgcgcg agcggacagg
    33901 attcgccggc gcgatcgcag ggcacgctgt agtgatgcga cacgtcgtag caggtgcgcc
    33961 cgatcacgct gcgcgcctcc ggccaggagc gccggtaggc ggcgttggcg gcgatgatgc
    34021 ggtagtcgcg gtcgcacagg atgtgcggtt cggggagggt ctcgaggaag gagaccagct
    34081 cgggcagcgg gcgggtttcg ggtggcatgc tctgtcagct gtgaccgttg atctgccacg
    34141 agtctgcctt gctgacagcc tgcgcgtcaa tcgacttgca cgctggatat ctcgaaaacc
    34201 cttgatttac atcaaatcca gaacatgacg cagcgctggc acgcgtcttg atagggaggt
    34261 cagggacaac cggagtccgc catgaacccg accgaccgcc gcttggtacg cgaaatcacc
    34321 ctcgtcatcg tgctcaagct gatcctcatc accgcgctgt ggtgggcctt catccgcgac
    34381 gcgaaggtgg cggtcgatcc aggcgccatg gccgcccagg ttgtcgcccc ggcaagcaca
    34441 aaacaacact cgacatctgg agaatcccat ggtcagtgag caactcgtcg acctgtcgcg
    34501 gctgcagttc gccgcgacgg cgatgtacca cttcctgttc gtgccgctca ccatcggcat
    34561 ggtgtggatg ctggtcatca tggaaagcgt ctatgtcatg accggcaaga cgatctacaa
    34621 ggacatgacc cgcttctggg gcaagctctt cggcatcaac ttcgcgctcg gcgtgaccac
    34681 cggcctgacg ctcgagttcc agttcggcac caactgggcc tactactcgc actacgtcgg
    34741 cgacatcttc ggcgcgccgc tggcgatcga ggggctgatg gccttcttcc tcgagtcgac
    34801 cttcatcggt ctgttcttct tcggctggga ccgcctgtcg cgccagcagc acctgctggt
    34861 gacgatcctg atggcggtgg gcaccaacct gtcggcgctg tggatcctga tcgccaacgg
    34921 ctggatgcag aatccggtgg gctcggagtt cagctacgag acgatgcgca tggagctcac
    34981 cgacttctgg gcagtggtgt tcaacccggt ggcgcagggc aagttcgtgc atacggtgtc
    35041 ggcgggctac gtgaccggcg cgatgttcgt gctgtcgatc tcggcctggt acctgctgcg
    35101 cgggcgtgac gtcgagttcg ccaagcgctc gtttcgcatc gcggcggcct tcggcttcgc
    35161 ctcgatctgc tcggtgatcg tgctcggcga cgaatccggc tacgcgctcg gcgaggcgca
    35221 gcagaccaag ctcgcggcga tggaggcgat gtgggagacc gaaccggccc cggccagctt
    35281 caacgtcatc gccgtgccca acgaggccga aatgaagaac gacttcgcca tccacatacc
    35341 gtgggtgatg ggcctgatcg gtacgcgctc gctcgacaag gagctgcccg gcctgaacca
    35401 gatctacgcg ctgaaccgcg agcgcgtgaa ggtgggcgtg gaggcggtga agctgctcga
    35461 ggcgctgcgc aagagcccgc aggacgcggc cctgcgcgag gccttcgaca gggtcaagga
    35521 cgacctcggc ttcggcctgc tgctgaagaa gtacgccgcc tcgatggacg acgtcacccc
    35581 cgagctgatc gaccgcgccg cgcgcgacac gctgcccaag gtgacgccgc tgttctggac
    35641 cttccgcatc atggtggcgc tgggcttcgc gatgctggcg ttgttcggcc tggcgctgtg
    35701 gtactcgatc aagggtgatt tcgcccagcg gccgtggctg ctgcgctggg cgctgtggtt
    35761 cctgcccatg ccgtggatct cgtgcgagat gggttggttc gtggccgagt acggccgcca
    35821 gccctggacc atctacggcg tgctgcccac ccacctgtcg gtgtcgacgc tgaccgtcaa
    35881 cagcctgtac ggctcgctcg ccggcttcgt cggcttctac accctgctgc tgatcgtcga
    35941 gatgtacctg atggtgaagt tcgcccgcca ggggccgggc agcctgggca ccggccgcta
    36001 cctgaacgaa acccaccacg cccacgcctg atcccggagc ggacatcatg atcttcgact
    36061 acccgacctt caaaatcatc tggtggctgc tggtgggcgt gctgctcgtc ggcttcgcca
    36121 tcatggacgg ccacgacatg ggcgtgggca cgctgctgcc cttcgtcggc agaaacgacg
    36181 aggagcgccg cgtcgtcatc aacaccgtcg gcccgcactg ggacggcaac caggtgtggt
    36241 tcatcaccgg gggcggcgcc atcttcgccg cctggccgat cgtctatgcg accgccttct
    36301 cgggcttcta ctgggcgatg ctggcggtgc tgtgggcctt gttcttccgc ccggtgggct
    36361 tcgactaccg cagcaagatc cacaacgcga cctggcgcag cacctgggac tgggggctct
    36421 tcatcggcgg tgcggtgccg ccgctgatct tcggcgtggc cttcggcaac ctgctgcagg
    36481 gcgtgccctt ccacttcgac gacaccctgg tgccctacta caccggctcg ttctggggtc
    36541 tgctcaatcc cttcgcactg ctggcgggcg tggtgagcac ggcgatgatc accttccacg
    36601 gcgcgatcta cctggcccac cgcaccgagg gcgacatcca gcgccgcgcg accacggccg
    36661 cgctgatctt cggcgtgctc atgctggtcg gcttcaccgc ggccgggctg tggatcgcca
    36721 acggcagctt cggctacgcg atcacctcgg tgctcgacac cgcggcgctg cccaacccgc
    36781 tcgccaagac ggtcgaactg cagcccggcg cctggctggc caactacgac aaggcgccgc
    36841 tgaccatgct ggtgccggcg ctggcctacg cgggcgggct cgccgcgttg ttgctggtgt
    36901 ggaaggggcg cacgctggcc gccttcgtcg cctcgtcgtt cgccatcatc ggtgtgatcg
    36961 gcaccgccgg cgtgtccatg ttccccttcg tgatgccctc ctccaccgtg ccgggcgcca
    37021 gcctcaccgt gtgggacgcg gtctccagcc atcgcacgct gggcatcatg ttctgggcga
    37081 cggtcatctt catgccgatc atcgtcgcct acacgagctg ggcctacagc gtgatggcgg
    37141 gcaaggtcac cgcggcctac atccgcgaaa acgaacattc cgcgtactga acacgcgcca
    37201 cgagcaagga gaacgacatg tggtatttcg cctgggtact gggcatcggt ttcgcggtgc
    37261 tgctggccat cctgaacgcg ctgtggggcg agaacgagga ggcgcgcgcc gccgccctcg
    37321 agcaggcacg cgcgcaggcg ggcgccggca aactgccacc ggcgggctga ggagcacacc
    37381 atgaagccgc acgcatccac tttcgccact gcggaagacg cgagcctcgg cctcgacgga
    37441 cccgcccctt ccagcgaggc gactcgcatc cgcctgttgc cgctgctgct cgccatcgcg
    37501 gtgatgctcg gcatcaccgc gtggccgggc gcgctcgccg gaccttcagg cgcggccgac
    37561 cacctcgcgg cgatggcgct gttctgggcg atgagtgccg gattcgtcgc cggagtcggc
    37621 ttccggccgc gcaagctcct gatccgcctg ctgttgtctc cgctcgcgtg ctggctcggc
    37681 gtgatcctgg ccggcctgcg gctggcgagc ctgacggcat gaggcggcgc aaaagctggc
    37741 gttccgcgat tttccttaac ctacgttaag tatttgctta tatagtattc gccgcacaca
    37801 cgacaggccg cacccgccgg gcgggcagcg gccgatccaa cctgaaggag gagaccatga
    37861 aggacctgcc gaaaagcccg ccggagctcc cggcgatcga tcccgagcgg cgacgcctgc
    37921 tgctcggggc ctcggccctg ccgctggcgg cgggcgccgg gctgagcctc gcgcccacgc
    37981 gcgcaagggc cgcgctcaag acctcggcgc gcatcgtgat tgccggcagc ggcctggccg
    38041 gcgtggccgc agccaaccgg ctcgcgcgcg aactcgacgg cgcgaagatc accatcgtcg
    38101 atcgcaagga gatccacaac taccagcccg gctacaccct ggtcgccacc ggggtatggc
    38161 cggtggaaaa ggtcagcgac cgcaacgccg acctgatccc gcccggcgtc gagtgggtgc
    38221 gcgagatggt cgccgagttc gacgccgaga agaacgcggt ggtcaccgac ggtgggcggc
    38281 gcatcgagta cgacttcctg atcgtcgcca ccggcctgca catggacttc ggactgatcg
    38341 agggcatgga cgtcgccgcg atcggccgca acgggctcgc cagcgtctat ccgagcccgc
    38401 aggcggcgca ggccacctgg caggcgatgg acaccttccg gcagaagggc ggcaaggcgc
    38461 tgatgaccct gcccgccacg ccgctcaagt gtgccggcgc gccgctgaag atgaccttca
    38521 tggtggtcga tcgcctccgc caggccggca cccgcgacca gtcgcaggtg agcttccact
    38581 ccgcgctcga caacatcttc agcgtgccgc gcatcaacca ggaagtgctc gagcgctgga
    38641 agaagctcga cgtgccggtg catttcctca gcaagctggt cgcggtcgac atcggcgcgc
    38701 gccgcgccac cttcgccagc cccgagggcg aacgcaccca gcacgactac gacttcatcc
    38761 acgtcgtccc gccgatgcgc gcgcccgatt cggtcaagaa cagcccgctg tcgtggaagc
    38821 aaggcccctt cgccgccggc gggacgacgt ggatgaagtc gtagtcgtgc tgggtgcg
//
LOCUS       DAOTIN010000022        38084 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_1162_length_38084_cov_8.869678, whole genome shotgun sequence.
ACCESSION   DAOTIN010000022 DAOTIN010000000
VERSION     DAOTIN010000022.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 38084)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 38084)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38084
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1162_length_38084_cov_8.869678"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..223
                     /locus_tag="P5537_05385"
     CDS             <1..223
                     /locus_tag="P5537_05385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV77508.1"
                     /translation="AGLGRAMSEVGAVTIVGGNIDGATRVMTTAIALETSKGDLALAI
                     ALGVVLIVIILALNALAYVLRQWAMRRFG"
     gene            232..966
                     /locus_tag="P5537_05390"
     CDS             232..966
                     /locus_tag="P5537_05390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HRV77509.1"
                     /translation="MPIFPLSIHDLRFAPDGREVLAGVDLELGEEGITLVLGPNGAGK
                     SVLLRTICGLLEPSAGRMAWGGAGGARPQQGVMMVFQRPMMLRMSVLDNVALGLKPLG
                     VAGAERRRRGVEMLERVGLADRAGDSARQLSGGEQQRLALARAWLTKPRLLLLDEPTA
                     SLDPSASAAVERIIREIRTDGTRILMVTHNLGQATRLGDDIVFMAGGRVCEHTPVRAF
                     FARPRSEEARLFIQGELPWRMRFQGA"
     gene            939..1220
                     /locus_tag="P5537_05395"
     CDS             939..1220
                     /locus_tag="P5537_05395"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77510.1"
                     /translation="MADALSRRLRSTLWAGGAVLLFGSVGVTCGIGVRQVEEARPVAG
                     GPHVAEEVERTSTAVVPSALHAADAPDGSGHDEARAAALTAGSAAQAPR"
     gene            1217..1468
                     /locus_tag="P5537_05400"
     CDS             1217..1468
                     /locus_tag="P5537_05400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77511.1"
                     /translation="MNATPARLPLAALVLFVLAALSLAAALLCFAGSGTLLHPALSDP
                     MAGLAFLVSAIALAGTGAFPLVFARLARRDAASKLPPGA"
     gene            complement(1494..1982)
                     /gene="moaC"
                     /locus_tag="P5537_05405"
     CDS             complement(1494..1982)
                     /gene="moaC"
                     /locus_tag="P5537_05405"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HRV77512.1"
                     /translation="MSTPESSPLTHFDADGQAHMVDVGAKAETRRVAVASGRIHMLPA
                     TFDMVKSGSAKKGDVLGIARIAAIQASKRTSELIPLCHPIPLTRVAVEFELDEAECAI
                     RCTVTAETVGRTGVEMEALTAVNVGLLTIYDMCKAVDRGMRMEGIQLMEKLGGKSGHW
                     KA"
     gene            2105..3544
                     /locus_tag="P5537_05410"
     CDS             2105..3544
                     /locus_tag="P5537_05410"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metalloprotease"
                     /protein_id="HRV77513.1"
                     /translation="MMRRPLALLLSLALALPAPVPVLAADLPDLGDVAASELSPAAER
                     RIGEQIIREIRWRDAAYLDDAEVEEYVNRLGQRLAAVSSNPGLDFDFFVVRDATLNAF
                     ALPGGFIGVHTGLILAAESESEFASVLGHEIAHVTQRHIAQIVGRQSQSAMLMIASML
                     VAVLAARSNSDVSQAAIAAGQAGAIQSQLGYTRAFEREADRAGLETLDKAGLDVRGMP
                     GFFERLQRNTRVYENNAPAYLRTHPLTTERIADMENRVASMRYRQVPDSADFRFARAK
                     LRANAGQPAEAVQELQDRLAREPKDEALAYGLARALMRAGRLDDAEARLQPLRAHSAG
                     AVWVEGLAAEIRLARNDPAGAIRILEAAQKQSPSTRSLSYALADARILGGRADAAATE
                     LRRRIGDRSGDPRLWQLLSRAYAALGKRTEQHRTQAEVYYLRGSLPAAIEQLEIARRA
                     NDGDFYTLSAVDARLRELKQRLLEEKRER"
     gene            3651..3881
                     /locus_tag="P5537_05415"
     CDS             3651..3881
                     /locus_tag="P5537_05415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusA family protein"
                     /protein_id="HRV77514.1"
                     /translation="MRYDKEVDARGLNCPLPILRAKKMLAEMQSGQIVRVLATDPGSV
                     KDFQAFSRQTGNELIGQGETSDKAYEFFLKRK"
     gene            complement(4274..7258)
                     /locus_tag="P5537_05420"
     CDS             complement(4274..7258)
                     /locus_tag="P5537_05420"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HRV77515.1"
                     /translation="MELAKSFEPADIERRWYPEWESRGYFDAGLDKSNPAAFCILLPP
                     PNVTGTLHMGHGFNQTIMDALTRYHRMRGDNTLWQPGTDHAGIATQIVVERQLDAQGV
                     SRHDLGRERFLEKVWEWKEYSGGTITRQMRRLGTSPDWKRERFTMDEGLSRTVTETFV
                     RLYNEGLIYRGKRLVNWDPKLGTAVSDLEVVSEEEDGKLYHILYPFSDGPIGELRGLT
                     VATTRPETLLGDVAVMVHPEDERYAHLIGKTVELPLTGRHIPIIADDYVDREFGTGCV
                     KVTPAHDFNDYAVGQRHKLDTIVVLTLEGAVPAVAERYTADGVTLESVPMPAGVAGLD
                     RVPARDKVVEELEALGLLLEVKAHKMQVPRGDRTGVVIEPMLTDQWFVAMSKPGADGK
                     SITEKALEVVASGEIKFYPENWVNTYNQWLNNIQDWCISRQLWWGHRIPAWYDEEGRI
                     YVATCEEEAIRAWKADLQRGIDALTAEVQTRQREGQTAEQYPEIAERLALLHARHDAG
                     HLRQEDDVLDTWYSSALWPFSTLDWTAEWPEKSNDALDLYLPSTVLVTGFDIIFFWVA
                     RMVMMTRHITGRIPFKHVYVHGLIRDAEGQKMSKSKGNVLDPIDLIDGIALDELIKKR
                     TFGLMNPKQAQSIEKKTRKEFPEGIPAFGTDALRFTFASLASPGRDIKFDLARCEGYR
                     NFCNKLWNATRFVLMNCEGHDCGIGEAVACTTEVLDFSFADRWIVSRLQRTEAEVAEH
                     FEAYRFDLVARAVYEFVWDEYCDWYLELAKVQIQSGTPAQQRATRRTLLRVLETVLRL
                     AHPLIPFITEELWQTVAPLAGRKDTDSLMQARYPQAEPKRIDEASEAKVAELKAMIYA
                     CRNLRGEMNISPAQRLPLVAAGDKAALALYAPYLAGLAKLAEVQVVDEIGADELAPVA
                     VAGETRLMLKVEIDVAAERERLGKEIARLEGEIAKAEGKLGNASFVDRAPAAVVQQER
                     DRLAGFKATVEKLKPQLVKLGG"
     gene            complement(7477..8148)
                     /locus_tag="P5537_05425"
     CDS             complement(7477..8148)
                     /locus_tag="P5537_05425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77516.1"
                     /translation="MKDWQDFPDDDELERADDLLGQADALLRRHRGDTAPSSPGTQRS
                     TDRDAAEPVHATPSGAAMQAFDDDDLPILTEVVDDLDLPTEIFQPTESSLAAAAAAQP
                     AFVRSLAPGEVSHARAPAAPPEPVDTFAQPAAPSPPPPPSVAAAEQQLAERLVELDTA
                     IAREIDEWAARELPQIIARELDRLGERIQDEALAHLRATLLPEISARVSSLFEDRRPD
                     HPPGR"
     gene            complement(8145..8585)
                     /locus_tag="P5537_05430"
     CDS             complement(8145..8585)
                     /locus_tag="P5537_05430"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004390392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit chi"
                     /protein_id="HRV77517.1"
                     /translation="MAPRVQFYHNTADRLALAHELVAGAYARGRKVALRCTDATQLRR
                     LDQVLWTAVPLDFVPHVGVASTLAAETPVVLGAAGEPCPWPHADMLFNLADDLPAEAD
                     GFRMVVEIVGRDAAEVHAARQRWAAYRQRGYELKAFDAERRVAL"
     gene            complement(8605..10104)
                     /locus_tag="P5537_05435"
     CDS             complement(8605..10104)
                     /locus_tag="P5537_05435"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0019538 - protein metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HRV77518.1"
                     /translation="MEFTIKTGSPAKLKTGLLVLGAFADGRLPALSAAADGAAEGRLA
                     TLIKRGDLDEKAGASVLVHDLPGVHAERVLLVSLGKHDEFGDKAFRDALAAAAKAISG
                     GPAKDAVVALADIELPGRDAAWRLQQATRMLADGAYRFDVLKSDKKAKKERGAKKLSL
                     LVSCELGAELDTAAMQGHAIAAGMALAKDLGNLPGNICTPTHLAETAEALGKQYKFEV
                     EVLEREDMEKLGMGSFLSVARGSHQPPKFIVMQYKGGKAKAKPVVLVGKGITFDTGGI
                     SLKPAAEMDEMKFDMCGAASVLGTFKAVAQMGLPINLVGLVPTTENMPGGGATKPGDV
                     VTSMSGQTIEVLNTDAEGRLILCDALTYAERFKPECVIDIATLTGACVVALGKIPSGL
                     LANDDELAAEILKRGTESGDRAWQLPLWDEYQELLKSNFADMGNIGGRYAGTITAACF
                     LARFTKAYKWAHLDIAGTAWVSGDAKGATGRPVPLLSSFLIGRARAHAA"
     gene            10243..11325
                     /gene="lptF"
                     /locus_tag="P5537_05440"
     CDS             10243..11325
                     /gene="lptF"
                     /locus_tag="P5537_05440"
                     /EC_number="7.5.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015221 - lipopolysaccharide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015920 - lipopolysaccharide transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptF"
                     /protein_id="HRV77519.1"
                     /translation="MIFRRALQREFAQTAAAVFVALFAILISTVLIRLLGQAAGGRVP
                     PDAVMALIGFGALAQLPTVLTLTLFIAVLVSLSRSYRDSEMVVWFASGVPLTAWIRPV
                     LLFALPIAVVAGAGSIYLSPWAQQKSGEYRERLESRDDTHRVAPGVFRESTSAQRVFF
                     VEVGAGEDGRVRNVFVSEQTRNGQLVVIASAEGYLRSDEEGRRFIVLEKGRRYDGTPG
                     TPEYRVMEFERYEVQVEQKQVAGQQARIRALPTAVLLAQPEARGLGELVGRFGVPLVA
                     LLLALMAIPLSFVNPRAGRANNMLVALLVYLVYSNAISVFQSWVAQGKLPFAAGLLLP
                     HVVVLAALALMFHKRLAISPFWRRRA"
     gene            11322..12398
                     /gene="lptG"
                     /locus_tag="P5537_05445"
     CDS             11322..12398
                     /gene="lptG"
                     /locus_tag="P5537_05445"
                     /EC_number="7.5.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015221 - lipopolysaccharide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015920 - lipopolysaccharide transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptG"
                     /protein_id="HRV77520.1"
                     /translation="MSPVLLRYLAREIFAASALVLVAFLGLFAFFDFINELEDVGKGG
                     YTLYQALVYVALTLPARVYELMPIAVLIGTLYALATLAKNSEITVMRASGMSNGLLMS
                     VLGLIGGVFAVLIFLIGEYVAPPAETAAEEWKLTATQATVSQQLRSGLWVKDGRLVIN
                     VRTLMPDRTMRGARVYAFDDDYALESIAEAATGVFDGSGEWKLLDVQRTRFHGDRTEV
                     ERLAEIRWRSELTPEVLGVLMVSPEHMPFGRLWTYINHLRDNNQNADRFEIALWKKLI
                     YPFTALVMMALAMPFGFIHDRMGGASARIFMGVMLGVGFHLLNGLFSNLGMINAWPPF
                     MAALTPSLIFLVAAFWLMHRVERR"
     gene            complement(12564..12971)
                     /gene="rplS"
                     /locus_tag="P5537_05450"
     CDS             complement(12564..12971)
                     /gene="rplS"
                     /locus_tag="P5537_05450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HRV77521.1"
                     /translation="MNLLQQLEQEEMARVSQGKTIPEFGPGDTVIVQVKVKEGNRERL
                     QAYEGVVIAKRNRGLNSSFIVRKISSGEGVERTFQTYSPLVAGVEVKRRGDVRRAKLY
                     YLRQRSGKSARIKEKLDYKAAAAKRAAQQQQEG"
     gene            complement(13069..13917)
                     /gene="trmD"
                     /locus_tag="P5537_05455"
     CDS             complement(13069..13917)
                     /gene="trmD"
                     /locus_tag="P5537_05455"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N(1))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HRV77522.1"
                     /translation="MNPHIPQGETQQASPPGVAGGPRRYDVVTLFPEMFAALTGSGIT
                     RRAIDRGLYALEFHNPRDFTSDPHRTVDDRPYGGGPGMVMLAEPLTQAIRAARAAQQA
                     ALGRSGRVIYLSPQGRRLAQEVVLELAAEPALVLLCGRYEGVDQRLIDREVDEELSLG
                     DFVLSGGELPAMVLLDAIVRQLPGALNTAGSAQEDSFADGLLDCPHYTRPELYEDERV
                     PDVLLSGNHAAIRRWRLKQSLGRTWLRRPDLLGARPLSKTELKLLDEFRQEQAGTQDA
                     LEPQRG"
     gene            complement(13938..14456)
                     /gene="rimM"
                     /locus_tag="P5537_05460"
     CDS             complement(13938..14456)
                     /gene="rimM"
                     /locus_tag="P5537_05460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300530.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HRV77523.1"
                     /translation="MIVLGRIVAPFGVQGWIKIHPFGDDPASWRKMSHWWLCSDDDAP
                     AEAWKQYTLTACRAHGKGLVAALAEVADRGAAEAVDGFYIGAPREALPKPAEGEYYWG
                     DLVGLAVENEAGEAFGTVAGLISTGAHDVLQVREGNGDEAVERLIPFVAAYVLDVDLA
                     TRRIRVAWQKDW"
     gene            complement(14485..14736)
                     /gene="rpsP"
                     /locus_tag="P5537_05465"
     CDS             complement(14485..14736)
                     /gene="rpsP"
                     /locus_tag="P5537_05465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004884679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HRV77524.1"
                     /translation="MVVIRLARGGAKKRPFFNMVVADSRNRRDGRFIERVGFYNPIAS
                     GAEKGLVINAERLAYWQQNGAQLSPTVARLVKQAATAAA"
     gene            14934..16442
                     /locus_tag="P5537_05470"
     CDS             14934..16442
                     /locus_tag="P5537_05470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77525.1"
                     /translation="MEAPSTPSDAEQSLLRWLESEPADAVEDDLAALRAHLLDAFGGA
                     GPGTNEVVLRALAERIGDIGARLRPLMIARQLPVEVALFEANEQLCALALDVAAAIAG
                     LAGSGSVARSGAEAELCEYAIGLVTEVFALCELAAAPPPAGTWRLAHDFAARRRIATA
                     APDDPLRCAYVRLLAVAVAQPEGLTGREIAWLYDFLDARVLSAAVLVHGVGDMSASAW
                     WIDLGADLAPQAVSRRPAPSGSMLGGEVWSFNPRPMAQKLGECIEWVTARMTAAELAG
                     MQGEVEPLTAEEDLFPPGLSPLETVALLRRLRSYWMAAPVRGQPRRQHQYVVQVGIGL
                     QAVWDLGGGGTAEVDSLQEWMVLNESPGGLAIMSVAGVRGEIEAGGALALRREQGQAW
                     SVCIVRWVRSDLPGQVEVGLQIIGQSFHPVMVGFRGRAVQQLSPALALPIMEPLRRHP
                     AMLAVAGTYASRRFVFVRETQTVYVAQARALGLDLQTPSVELFQYEIDPYPI"
     gene            16532..17131
                     /gene="wrbA"
                     /locus_tag="P5537_05475"
     CDS             16532..17131
                     /gene="wrbA"
                     /locus_tag="P5537_05475"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003955 - NAD(P)H dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H:quinone oxidoreductase"
                     /protein_id="HRV77526.1"
                     /translation="MHEILVLYYSHRGSVRALAEHIAAGIHQVPGAVARVRTVPRVST
                     VCEAVEDDIPASGPPYVEVADLEECVGLALGSPTRFGNMAAPMKYFLDGLAGAWLNGA
                     LEGKPGCVFTSSSSLHGGQESTLLSMMLPLFHHGMLVLGLPFSEPALGETRTGGTPYG
                     ASHVSGSEGDAALSAEEIALAQAQGRRLAEVAMRLAGAR"
     gene            17128..>17473
                     /locus_tag="P5537_05480"
     CDS             17128..>17473
                     /locus_tag="P5537_05480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2069 domain-containing protein"
                     /protein_id="HRV77527.1"
                     /translation="MNARALSLVSSAALLALIVLCVVWEGWLAPLRPGGSWMMLKALP
                     LLPAVFGVLRGRRYTSQWLSMLSLLYFTEGVLRASDPGLTGVFALTEVFLAVVLFTST
                     MLHARATAPSRAQ"
     assembly_gap    17474..17573
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(17706..19241)
                     /locus_tag="P5537_05485"
     CDS             complement(17706..19241)
                     /locus_tag="P5537_05485"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011239827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HRV77528.1"
                     /translation="MKDKLIIFDTTLRDGEQSPGASMTRDEKLRIARQLERMRVDVIE
                     AGFAAASNGDFEAVRSIAEAIKESTVCTLARANEHDIRRAGEAIRPAARGRIHTFIAT
                     SPIHMEKKLRMTPDEVVAQAVKAIGWAREYTDDVEFSAEDAGRSEIDFLVRIFEAVID
                     AGAKTINVPDTVGYNVPEQFATTVGTLIERVPNSDRVVWSVHCHNDLGLAVANSLAAV
                     RAGARQVECTINGLGERAGNASLEEIVMAVRTRADIFPVETGIDTTQIVPASKLVSQI
                     TGYPVQPNKAIVGANAFAHESGIHQDGVLKHRETYEIMRAEDVGWGANKLVLGKLSGR
                     NAFRARLQELGIEIESEEHLNQAFARFKELADRKSEIFDEDLTALMRDEAVTPAPEQY
                     RLVSTRFHSETGETPVAEITLSIGGAEKQARANGSGPVDAAFKAIETVATTGSELLLY
                     SVNAITSGTDAQGEVTVRLSRDGRVMDGQGADTDIIVASAKAYLNALNKLHAGAERLN
                     PQV"
     gene            complement(19238..20128)
                     /gene="pssA"
                     /locus_tag="P5537_05490"
     CDS             complement(19238..20128)
                     /gene="pssA"
                     /locus_tag="P5537_05490"
                     /EC_number="2.7.8.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003882 - CDP-diacylglycerol-serine
                     O-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--serine
                     O-phosphatidyltransferase"
                     /protein_id="HRV77529.1"
                     /translation="MTILDSTEATPKVPDIEHAPLPLPDKRRRGIYILPNLFTTAALF
                     AGFYAIVQAMNQRFEYAAVAIFVAMVLDGLDGRIARLTNTQSEFGAEYDSLSDMVSFG
                     AAPALVMYEWALQDLGKLGWVAAFIYCAGAALRLARFNTNIDVVDKRYFQGLPSPAAA
                     ALVAGMVWVGIDNGFAGDDLRWYAAVLTIFAGVSMVSNVLFWSGKSINLRKSVPFIVL
                     IALVLAFALISSYPPGILFALFLAYAGSGYIVAALRWRRRRSHRAEPASPASPTHTEQ
                     AGDTAAAPVEGASSDPGSKP"
     gene            complement(20270..21286)
                     /gene="ilvC"
                     /locus_tag="P5537_05495"
     CDS             complement(20270..21286)
                     /gene="ilvC"
                     /locus_tag="P5537_05495"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011239815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HRV77530.1"
                     /translation="MKVYYDKDADLSLIKGKQVTIVGYGSQGHAHAQNLRDSGVNVTV
                     GLRKDGSSWAKAEAAGLAVKEIGEAVKAADLVMILLPDETAPQVYRDDIEPNIKKGAV
                     LAFAHGFNVHYNQIVPRADLDVIMVAPKGPGHTVRSEYLRGGGVPTLIAIYQDRSGKA
                     KDIALSYSAANGGTKGGVIETNFREETETDLFGEQAVLCGGAVELVKMGFETLVEAGY
                     APEMAYFECLHELKLIVDLMYEGGIANMNYSISNNAEYGEYVTGPEVINEQSRAAMRN
                     ALKRIQTGEYAKMFILEGKTNYPSMTAYRRLNADHQIEKVGGQLRDMMPWIKAKALVD
                     KSKN"
     gene            complement(21328..21819)
                     /gene="ilvN"
                     /locus_tag="P5537_05500"
     CDS             complement(21328..21819)
                     /gene="ilvN"
                     /locus_tag="P5537_05500"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HRV77531.1"
                     /translation="MRHVISLLIENESGALSRVSGLFSARGYNIESLTVAPTEDFSMS
                     RMTIVTTGSDEIIEQITKQLNKLVEVVKVVDISEAAHIERELMLVKVRATGKDREEIK
                     RTADIFRARIIDVTDASYVVELTGNQGKLDAFIGAIDPALILETVRSGVCGIGRGDRV
                     LKV"
     gene            complement(21851..23563)
                     /locus_tag="P5537_05505"
     CDS             complement(21851..23563)
                     /locus_tag="P5537_05505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011766879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 3 catalytic subunit"
                     /protein_id="HRV77532.1"
                     /translation="MVLSGAEIVIRCLQEEKVEYVFGYPGGAVLFLYDALFQQDKVRH
                     VLVRHEQAAVHAADGFARSTEKVGVAMVTSGPGATNAVTGIATAYCDSIPMVIISGQV
                     PVAAIGQDAFQEVDTVGITRPCVKHNFLVKDVRDIAATMKKAFHLARTGRPGPVLVDI
                     PKDVSMQRCEYEYPKEISMRSYNPVTKGHSGQIKKAVQLLLEAKRPMIYTGGGVVLSN
                     AAEPLTKLTRLLGYPITNTLMGLGGYPSSDRQFLGMPGMHGTFEANMAMHYSDVLLAV
                     GARFDDRVIGNPAHFAEEPRKIIHVDIDPSSISKRVRVDTPIVGDVKEVLEEMIRQLE
                     SGEARPNPEALAAWWKQIEQWRDRKCMVYKNSDEIIKPQFVIQKLWEVTGGDAIITSD
                     VGQHQMWAAQYYGFDKPRRWLNSGGLGTMGVGMPYAMGAKLANPDVPVACVTGEASIQ
                     MNIQELSTCKQFRLPIKICNLNNRYLGMVRQWQELFHGGRYSESYMDSLPDFARLAEA
                     YGHVGIRVDRPADVEGALREAFTTHRNELVFLDFQIDQTENVYPMVQGGKGLTEMILS
                     AEDL"
     gene            23832..24386
                     /locus_tag="P5537_05510"
     CDS             23832..24386
                     /locus_tag="P5537_05510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HRV77533.1"
                     /translation="MTRSKSRAGKAAPDGVPAAQPPARDALNRKDTAGATASDRPSAE
                     LAGLRRRLASMLYESMLLLGVLALTFLVPYLMLGIAAEFAPPGWLLWLHVFGVLGVYF
                     VWYWRRGGQTLAMQTWRLKIVTAADGRIASLGRCWLRYALAWSSVLLGGIGLAWALVD
                     RDRQFLHDRLAGTCIVLLPTPAKG"
     gene            24531..26276
                     /locus_tag="P5537_05515"
     CDS             24531..26276
                     /locus_tag="P5537_05515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HRV77534.1"
                     /translation="MAAMLAHGPYAEFAVLLIISALAGAIAVRLRQPVLIAYIVVGIL
                     VGPAVFGIVTAHDQVALLAEIGVTVLLFVVGLKLDLHHIRHIGPVALATGLGQLGFTI
                     VFGFLIIVLMGKSLMEALYVAVALTFSSTIIVVKLLSDKRELDSLHGRIAVGFLIVQD
                     VAVVLAMMTMSALRGAGEDAVLAVAGQLALRLVGATALMFVLMRYVLPWLVHAMARSQ
                     ELLLIFAIAWGTGLAALGEVAGFSKEAGAFMAGFSLASTAYREAMNARLTGIRDFMLL
                     FFFVDLGAKLDFSTLGGELWPAVILSLFVLIGNPLIVMAIMGYMGYRKRTGFMAGLTV
                     AQISEFSIVFVAMGITLGHIGVEALGLTTLVGLVTIMMSTYLILYSQPLYERLAPVLG
                     VFERKRPFRELAVERQGRAAGQPDIVVFGLGRYGARLMRQLRQAGIEVLGVDFDPEIV
                     RQLRRQRLPVRFGDGEDPGFLESLPLADARWVVTTFPQWDSNRAFLHALGEAGFKGRI
                     AGVVRDDIHGAALGAAGVERVLNPFNDAADYAARTFAAEIAYEDAHRADIADAAGTQA
                     AAPARPPARPQETER"
     gene            26273..27169
                     /locus_tag="P5537_05520"
     CDS             26273..27169
                     /locus_tag="P5537_05520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HRV77535.1"
                     /translation="MNPIRTVVAPTDLSALARHAVVRACLLAAELGARLSLQHVVNAG
                     ALDTLRHLLDADAAGVQEKLLAEVRGEVEALAAEMHRRHGVVPEQQLAVGSVLGEIVA
                     HAEAVDADLLVMGARGAGFMRELLIGSTTERVLRKSVRPMLVVKQIAHEPYRRVLVPV
                     DFSARALEALQFAQCVAPQAEFVLLHAFEVPFEGKLRYAGVEENALSSLRVNARREAG
                     AQMKELVACAGLDENRVRRIVVHGEATTQILEQEQEQDCDLIVIGKRGHGLLGEMLLG
                     SVTKHVLARSTADVLVCDRKPD"
     gene            27327..30002
                     /gene="pepN"
                     /locus_tag="P5537_05525"
     CDS             27327..30002
                     /gene="pepN"
                     /locus_tag="P5537_05525"
                     /EC_number="3.4.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004373859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase N"
                     /protein_id="HRV77536.1"
                     /translation="MKTEHAPTIQRADYRPLAWTVETVDLHFRLDPEATLVTNRMCCV
                     RNRDAADGPIRLWGEVLERVSLTVDGQPPQGLHEDGGAIDIDAAGDRVVVEVVTRVDP
                     RANTTLSGLYLSNGGFFTQCEAEGFRRITCFPDRPDVMARYTVTLEADRDACPVLLSN
                     GNLVDEGLLPEGRHYAKWEDPFPKPSYLFALVAAKLVALERTVTTMSGREVLLQVWVE
                     EGNLDRVEHAMDSLVHSMRWDEETFGLELDLDRFMIVAVADFNMGAMENKGLNIFNTK
                     FILAKPDTATDLDYENVESVVAHEYFHNWTGNRVTCRDWFQLTLKEGLTVFRDQQFSA
                     DMLARAAGPEGAASARAVKRIDDVRVLRAAQFPEDGGPMAHPIRPDSYQEINNFYTAT
                     VYEKGAEVIRMLHTLLGQEGFRNGMDLYFSYFDGQAVTCDDFVEVMSEANNGFDLDQF
                     MRWYEQAGTPRVKASGVWNAADDSYTLTLAQSTPATPGQHVKQPLVIPVAVGLIGADG
                     RDLPLQLEGEAQAGACTRVLKLTEDEQTFRFVGVAAEPVPSLLRGFSAPVILELDEDD
                     ARLAFRMAHDADPCNRWDAAQRYAERVVLDLAADAGAEVPDAFVAAFRTLLNDGALDP
                     AFRAQALALPGEAYLLERMSPADPAALRSALVRMMRALGATLTADWLEVVERLQVRGE
                     YRYHPGDAGRRALVNLALRYLAAAGVAEGLALAEARFAAATNMTERFGALAALVQSTS
                     PARAAALQAFHDRHRGDALVLDKWFALQAGAWRWGEEAEPALARVRVLLSDPAFSLSN
                     PNKVYALLGTFFRANPGEFHAADGSGHAFWAEQVIALDARNPQVAARVARALENWRHF
                     TPALQASIRPQLERVLAAPGLSADVAEIVGKALGA"
     gene            complement(30143..30589)
                     /locus_tag="P5537_05530"
     CDS             complement(30143..30589)
                     /locus_tag="P5537_05530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HRV77537.1"
                     /translation="MMTTVKQILEAKGGTFHAVRPTDSVFDALSLMAQFDIGCVLVTD
                     GDKLVGIFTERDYARKVVLKGLVSRDVKVGDLMTPNPYTVSLTGTADDVMATMTAKRF
                     RHIPVVEEGKVIGIVTIGDMVKSIVTQHEKTIKQLESYIAGDLAAE"
     gene            complement(30723..31550)
                     /gene="panC"
                     /locus_tag="P5537_05535"
     CDS             complement(30723..31550)
                     /gene="panC"
                     /locus_tag="P5537_05535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004592 - pantoate-beta-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HRV77538.1"
                     /translation="MQIHETIDSLRAARAGAGRVAFVPTMGNLHEGHIALMRQARDHA
                     GCVVASIFVNRLQFGAGEDFERYPRTFAADCEKLAAAGVEHLFAPDESVMYPQPQRYH
                     VDPPAEQVSILEGEFRAGHFRGVATVVMKLLNIVQPEVALFGKKDYQQLMVLSNMVRE
                     LAMPIEVVAGETVRAVDGLALSSRNGYLSADERARAPLLHRLLAGIRDAVRAGGRDFA
                     QLEADAMAELGAAGWAPDYIAVRRRLDLQPPTQTDEALVVLAAAKLGRTRLIDNLEI"
     gene            complement(31580..32395)
                     /gene="panB"
                     /locus_tag="P5537_05540"
     CDS             complement(31580..32395)
                     /gene="panB"
                     /locus_tag="P5537_05540"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011766869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003864 - 3-methyl-2-oxobutanoate
                     hydroxymethyltransferase activity [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HRV77539.1"
                     /translation="MSYLQDQKPVTLFELGKMRAEGRKIAMLTAYDASFAALLGRAGV
                     DSILIGDSLGNVLQGQKSTLPVTLEQMAYHTECVARAGARPFVVTDMPFGSYHENREQ
                     AMRNAARLMAAGAQMVKLEGGAFMAETVRFLVERGVPVCAHIGLTPQAVHQLGGYRVQ
                     GRSEEGAARLKADALALEQAGAALMVMEMVPAALAGEITASLSSMATIGIGAGAACDG
                     QVLVLHDLLGVFPGKTARFVRNFMDGAASIEEAVARYVATVKDGSFPAAEHCY"
     gene            complement(32485..33123)
                     /locus_tag="P5537_05545"
     CDS             complement(32485..33123)
                     /locus_tag="P5537_05545"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004373863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0019136 - deoxynucleoside kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HRV77540.1"
                     /translation="MLDKARYIVVEGPIGAGKTSLARRLADRLQAEAVFEQAELNPFL
                     GRFYQQSERWGLATQLSFLFQRIDQLAALGPIEGERRVVADFLFDKDHLFAEQNLSPD
                     ELALYRRVHDGLQPRNAPRPDLVIYLQARPDTLMERIRKRGLDAERRITELYLEQVAE
                     RYTRYFYQYDAAPLFIVDAGKLNPVDRDEDFELLLERLREMRSYREFFGYAD"
     gene            complement(33152..33523)
                     /locus_tag="P5537_05550"
     CDS             complement(33152..33523)
                     /locus_tag="P5537_05550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004373864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family protein"
                     /protein_id="HRV77541.1"
                     /translation="MAAWIQSVSSIPVWVQTALLLTASNVFMTFAWYGHLKNMQTKAW
                     YVAALVSWGIALFEYLLQVPANRIGATTLSLAQLKIMQEVITLLVFVPFVVLYMKQPL
                     KLDYLWAALCMLGAVYFIFRN"
     gene            complement(33542..34045)
                     /gene="folK"
                     /locus_tag="P5537_05555"
     CDS             complement(33542..34045)
                     /gene="folK"
                     /locus_tag="P5537_05555"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HRV77542.1"
                     /translation="MIRAYVAFGANLGDPAAAFADALQRLDALPGTRVVASSSLYRSA
                     PVGVAGQPDYFNAVIALDTTLAPRPLLEALLAIEHDAGRRRDFPMAPRTMDLDLLLHG
                     DAVIDEPGLQVPHPRMHERAFALLPLAEIDPAASIPGRGAIAALLPALAGQAIERVPP
                     PAASPRP"
     gene            complement(34056..35426)
                     /gene="pcnB"
                     /locus_tag="P5537_05560"
     CDS             complement(34056..35426)
                     /gene="pcnB"
                     /locus_tag="P5537_05560"
                     /EC_number="2.7.7.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004381887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004652 - polynucleotide
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006378 - mRNA polyadenylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polynucleotide adenylyltransferase PcnB"
                     /protein_id="HRV77543.1"
                     /translation="MIRKLLRKVFKRPATPARHEPAIIPVERHGIRREQLSPAARKVC
                     AVLQEKGFKAFVVGGAVRDLLIGQPPKDYDVATSATPEEVRAAFRRSRIIGRRFKIVH
                     VMSGPETIEVSTFRASQDAESAETDEHGRVLRDNVFGSQQEDATRRDFTVNALYYDPG
                     TETIVDYHHGVADIQQKTLRMIGDPRTRYREDPVRMLRAVRLAAKLGLTIDPAARQPI
                     REMGPLLENVPAARLFDEMLKLLFSGHSLKCLQQLRGEGLHHGLLPLLDVILEQPMGE
                     RFVTLSLENTDERVRQDKSVSPGFLFSTLLWHEVLKTWENKKAAGDHSQPALFEAMDE
                     VLDAQAGKLAITRRIAGDIKDIWALQPRFDKRAGKAPYRVIEQPRYRAGWDFLRLRAQ
                     AGEIPMEIVDWWDDFAHAGPDRREALLRQAPPDAAPAAKKRRRRKRKPAGENAAAAEA
                     TLADPS"
     assembly_gap    35636..35735
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(36003..36665)
                     /locus_tag="P5537_05565"
     CDS             complement(36003..36665)
                     /locus_tag="P5537_05565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HRV77544.1"
                     /translation="MNLVLFDLDNTLLAGDSDFAWAQFLIGKGVLDREVQEAKNIEFY
                     EQYKAGTLDIFAFLDFQLAPLARHPREQLDAWHSEFMTRSIRPMITPKARTLVREHLD
                     SGALVAVVTATNAFVTGPIVREFGIPHVVATIPAQQDGAFTGKPRGTPAFKAGKIERV
                     DAWLESLGLHLGSFEHSWFYSDSHNDLPLMQRVTDPVAVDPDPTLRAHAESAGWPVIS
                     LR"
     gene            complement(36745..37437)
                     /gene="hda"
                     /locus_tag="P5537_05570"
     CDS             complement(36745..37437)
                     /gene="hda"
                     /locus_tag="P5537_05570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0032297 - negative regulation of
                     DNA-templated DNA replication initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DnaA regulatory inactivator Hda"
                     /protein_id="HRV77545.1"
                     /translation="MKQLVLDIRPDAPPTLENFVAGANAELVATVSLLTSPAMAAQLP
                     ARHIYLWGAPGSGRSHLLRAAVDAARTAGRPAHLLAAATVEDDLPETPDALLAIDDVD
                     QLGAAAQIALFNAFNRARGNGQSLLLCGPAAPLGLALREDLRTRIGQSLIYQVQPLDD
                     AARAEILATLAARRGLRLADEVVDFLLRHGRRELSSLREVLDALDRASLEHKRPITLP
                     LLRDMIQQGLEI"
     gene            complement(37434..>38084)
                     /locus_tag="P5537_05575"
     CDS             complement(37434..>38084)
                     /locus_tag="P5537_05575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HRV77546.1"
                     /translation="MAVLGFAANVLLIPLVMFYLLQEWPRILDELERIVPRPWVATTT
                     RILAEIDSVMSEFLRGQLSVMLLLAVFYSAGLWLAGLNFWLPVGVLTGLLVFIPYVGF
                     GGGLILAIVAALLQAQGWPPLIGVAIVYALGQLVESFLLTPYLVGERIGLHPLAVIFA
                     LMAFGQLFGFVGVLVALPVGAALLVGLREVRQAWLASPVYLGTQPRPVIARELERP"
BASE COUNT         5254 a        12764 c        13648 g         6218 t
ORIGIN      
        1 cgcgggcctg gggcgggcga tgagcgaggt gggcgcggtg acgatcgtcg gcggcaacat
       61 cgacggcgcc acccgggtca tgaccaccgc gatcgcgctc gagaccagca agggcgacct
      121 ggcgctggcg atcgcgctcg gcgtcgtgct gatcgtgatc atcctcgcgc tcaacgcgct
      181 cgcctacgtg ctgcggcagt gggcgatgcg gcgcttcggg tgagccctgc catgccgatc
      241 ttcccgctct ccatccacga cctgcgcttc gcgcccgacg ggcgggaggt gctcgccggc
      301 gtggacctgg agctgggcga ggagggcatc acgctggtgc tcggccccaa cggcgccggc
      361 aagagcgtgc tgctgcgcac gatctgcggg ctgctcgagc cgagcgcggg ccgcatggcc
      421 tggggcggcg ccggcggtgc gcggccgcag cagggggtga tgatggtgtt ccagcgcccg
      481 atgatgctgc gcatgtcggt gctcgacaac gtcgccctcg ggctcaagcc actcggcgtg
      541 gccggcgcgg agcggcgccg gcgcggcgtg gagatgctcg agcgcgtcgg cctcgccgac
      601 cgcgccggcg acagcgcgcg ccagctctcc ggcggcgagc agcagcgcct cgcgctcgcg
      661 cgcgcctggc tcaccaagcc gcgcctgctg ctgctggacg agcccaccgc cagcctagac
      721 ccctcggcga gcgccgcggt cgagcgcatc atccgcgaga tccgcaccga cggcacgcgc
      781 atcctcatgg tcacccacaa cctcggccag gccacccgcc tgggcgacga catcgtcttc
      841 atggcgggcg gccgggtgtg cgagcacacc ccggtgcgcg ccttcttcgc tcgtccgcgc
      901 tccgaagagg cgcggctctt catccaggga gaactgccat ggcggatgcg ctttcaaggc
      961 gcctgaggtc cacgctgtgg gccggcggcg cggtgctgct gttcggcagt gtcggcgtca
     1021 cctgcgggat cggcgtgcgg caggtggagg aggcgcggcc tgtggcggga gggccgcacg
     1081 tggcggagga ggtggagcgg acgagcactg ccgtcgtgcc gtccgcgctc cacgctgcgg
     1141 acgcgccgga cgggtcgggc cacgatgagg cgcgcgcggc cgcccttacg gccggaagcg
     1201 cggcgcaggc gccacgatga acgccacgcc cgcccgcctg ccgctcgccg ccctcgtgct
     1261 gttcgtgctc gcggcgctgt cgctcgcggc cgcgctgttg tgcttcgccg gttccggcac
     1321 gctcctgcac ccggccctgt ccgacccgat ggccgggctg gccttcctcg tctcggcgat
     1381 cgcgctcgcc ggcaccggcg ccttcccgct ggtcttcgcg cgcctcgcgc ggcgcgacgc
     1441 agcctcgaag ctgccgcccg gcgcctgact cttcacgcct tactcctgac gcctcacgcc
     1501 ttccagtgcc ccgacttgcc gcccagcttc tccatgagct ggatgccctc catgcgcatg
     1561 ccgcggtcca ccgccttgca catgtcgtag atcgtgagca ggccgacgtt gaccgcggtg
     1621 agcgcctcca tctcgacgcc ggtgcggccg acggtctcgg cggtgaccgt gcagcggatc
     1681 gcgcattcgg cctcgtcgag ctcgaactcg accgcgacgc gggtgagcgg gatggggtgg
     1741 cagagcggga tcagctcgct ggtgcgcttg gaggcctgga tcgcggcgat gcgggcgatg
     1801 ccgagcacgt cgcccttctt cgcgctgccc gacttcacca tgtcgaaggt ggcgggcagc
     1861 atgtggatgc ggccgctggc gacggcgacg cgacgggtct cggccttggc gccgacgtcg
     1921 accatgtggg cctggccgtc ggcgtcgaag tgggtcagcg ggctggattc cggagtgctc
     1981 atggtggggc agggcagaag attcggaggt gccgcggcgg aaaacgcccc gcggcgagag
     2041 cgccgctaca cgccgataca tcggcgcggg aacgggcgcg ggtcggcggg tatcatagca
     2101 cccgatgatg cgccgacccc ttgccctgct gctcagcctc gccctggccc tgcctgcgcc
     2161 ggtgcccgtg ctcgccgccg atctgcccga tctcggcgac gtggccgcgt ccgaactctc
     2221 gccggcggcc gagcgccgca tcggcgagca gatcatccgc gagatccgct ggcgcgacgc
     2281 cgcctacctc gacgatgccg aggtcgagga gtacgtgaac cgcctcggcc agcgcctcgc
     2341 cgcggtgagc agcaatccgg gactggactt cgacttcttc gtcgtgcgcg acgccacgct
     2401 caacgccttc gcgctgcccg gcggcttcat cggcgtgcat accgggctga tcctggcggc
     2461 ggagagcgag tccgagttcg cctcggtgct tggccacgag atcgcccacg tcacccagcg
     2521 ccacatcgcg cagatcgtcg gcaggcagag ccagtcggcg atgctgatga tcgcctcgat
     2581 gctggtcgcg gtgctggccg cgcgcagcaa ctcggacgtc agccaggccg cgatcgccgc
     2641 cggccaggcc ggggcgatcc agtcgcagct cggctacacc cgcgccttcg agcgcgaggc
     2701 cgaccgcgcc ggcctggaga ccctggacaa ggccggcctc gacgtgcgcg gcatgcccgg
     2761 cttcttcgag cgcctgcagc gcaacacgcg cgtctacgag aacaacgcgc ccgcctacct
     2821 gcgcacccac ccgctgacta ccgagcgcat cgccgacatg gagaaccgcg tcgcctcgat
     2881 gcgctaccgc caggtgccgg actcggcgga tttccgcttc gcacgcgcca agctgcgtgc
     2941 caacgccggc cagcccgccg aggcggttca ggaactgcag gaccgcctcg cgcgcgagcc
     3001 gaaggacgag gcgctggcct atgggcttgc ccgggcgctg atgcgggccg ggcgcctgga
     3061 tgacgccgag gcccgcctgc agccgctgcg cgcgcactcc gcgggcgcgg tgtgggtgga
     3121 ggggctggct gcggagatcc gcctcgcgcg caacgacccc gcgggggcga tccgcatcct
     3181 cgaggccgcg cagaagcagt ccccgtccac ccgcagcctg agctacgcgc tcgccgatgc
     3241 gcgcatcctg ggcggaaggg cggacgccgc cgcgaccgaa ctgcgccgcc gcatcggcga
     3301 ccgcagcggc gatccgcgcc tgtggcagct gctgtcgcgc gcctacgccg cgctcggaaa
     3361 gcgcaccgaa cagcatcgca cccaggccga ggtgtattac ctgcgcggca gcctgccggc
     3421 cgcgatcgag cagctcgaga tcgcgcgccg cgccaacgac ggtgacttct atacgctgtc
     3481 ggcggtggat gcgcgcctgc gcgagctcaa gcagcgcctg ctcgaggaaa agcgcgagcg
     3541 ctgagcggcc ttgtgccgca ggtcgcacgg cgtgacgggc gcgccttccg gggcgcatgg
     3601 ccatccttta gaatcggccg ccttcaatac gaccctatca gggagcggac atgagatacg
     3661 acaaggaagt ggatgcgcgc gggctcaact gcccgctgcc gatcctgcgg gccaagaaga
     3721 tgctggccga gatgcagagc ggacagatcg tccgcgtgct cgcgaccgat ccgggctcgg
     3781 tgaaggattt ccaggccttc tcccgccaga ccggcaacga gctgatcggc cagggcgaga
     3841 cgtccgacaa ggcgtacgag ttcttcctga agcggaagta gcgccgcctt cgcgcctgcc
     3901 ggcgctccta catgaaccat cgcggctccc gcctcctgta ggagcggcgg cagccgcgaa
     3961 catggcggtg gggcggcggt gggcgttgtc gggttgggtc ggctgcattc gcgcctgccg
     4021 gcgctcctac atgaaccatc gcggctcccg cctcctgtag gagcggcggc agccgcgaac
     4081 atggcggtgg ggcggcggtg ggcgttgtcg ggttgggtcg gctgcattcg cgcctgcccg
     4141 cgctccgaca tgaatcatcg cgcgtccggg aggcatgtcg gagcggcgcg ggtcccgcct
     4201 cctgtaggag cggcggcagc cgcgaaccgg ggttcagagg ctgcgggcgc tgcgacgccc
     4261 gcgtgcgcgt tcctcagccg ccgagcttca ccagctgcgg cttgagcttc tccaccgtgg
     4321 ccttgaagcc cgcgaggcgg tcgcgttcct gctgcaccac cgcggccggg gcgcggtcga
     4381 cgaagctggc gttgccgagc ttgccttcgg ccttggcgat ctcgccttcg aggcgggcga
     4441 tctccttgcc caggcgctcg cgctcggcgg cgacgtcgat ctccaccttg agcatcaggc
     4501 gcgtctcgcc ggcaaccgcg accggagcga gctcgtcggc gccgatctcg tccacgacct
     4561 gcacctcggc gagcttggcc aggccggcga ggtagggcgc gtacagcgcc agcgccgcct
     4621 tgtcgcccgc ggccaccagc ggcaggcgct gcgccgggga gatgttcatc tcgccgcgca
     4681 ggttgcggca ggcgtagatc atggccttga gttcggcgac cttcgcctcg gaggcctcgt
     4741 cgatgcgctt gggctcggcc tgcgggtagc gcgcctgcat caggctgtcg gtgtccttgc
     4801 gccctgcgag cggggcgacc gtctgccaga gttcctcggt gatgaagggg attagcgggt
     4861 gcgccaggcg cagcacggtc tcgagcacgc gcagcagcgt gcggcgggtg gcgcgctgct
     4921 gggccggagt gccggactgg atctgcacct tggcgagctc gaggtaccag tcgcagtact
     4981 cgtcccagac gaactcatac accgcacgag cgacgaggtc gaagcggtag gcctcgaagt
     5041 gttccgccac ctcggcctcg gtgcgctgca ggcgcgacac gatccagcgg tcggcgaagg
     5101 agaagtcgag cacctcggtg gtgcaggcga cggcctcgcc gatgccgcag tcgtggcctt
     5161 cgcagttcat cagcacgaag cgggtggcgt tccacagctt gttgcagaag ttgcggtagc
     5221 cctcgcagcg cgcgaggtcg aacttgatgt cgcggccggg gctggcgagg ctggcgaagg
     5281 tgaagcgcag cgcgtcggtg ccgaaggcgg gaatgccctc ggggaattcc ttgcgcgtct
     5341 tcttctcgat gctctgcgcc tgcttggggt tcatcaggcc gaaggtgcgc ttcttgatca
     5401 gctcgtcgag cgcgatgccg tcgatgaggt cgatcgggtc gagcacgttg cccttggact
     5461 tgctcatctt ctggccttcc gcgtcgcgga tcaggccgtg cacgtaaacg tgcttgaacg
     5521 ggatcctgcc ggtgatgtgc ctggtcatca tgaccatgcg cgctacccag aagaagatga
     5581 tgtcgaagcc ggtgacgagc acggtcgacg gcaggtagag gtcgagcgcg tcgttgctct
     5641 tctccggcca ctccgccgtc cagtcgagcg tggagaacgg ccacagcgcg gacgagtacc
     5701 aggtgtcgag cacatcgtct tcctggcgca ggtggccggc gtcgtggcgg gcgtggagga
     5761 gggcgaggcg ctcggcgatc tcggggtact gctcggcggt ctggccttcg cgctggcgtg
     5821 tctgcacctc ggcggtgagc gcgtcgatgc cgcgctgcag gtcggccttc caggcgcgga
     5881 tcgcctcttc ttcgcaggtg gcgacgtaga tgcggccttc ctcgtcgtac caggccggga
     5941 tgcggtggcc ccaccacagc tggcgcgaga tgcaccagtc ctggatgttg ttgagccact
     6001 ggttgtaggt gttgacccag ttctcggggt agaacttgat ctcgcccgag gccacgacct
     6061 cgagcgcctt ctcggtgatc gacttgccgt ccgcgccagg cttggacatg gcgacgaacc
     6121 actggtcggt gagcatcggc tcgatgacga cgccggtgcg gtcgccgcgc ggcacctgca
     6181 tcttgtgcgc cttgacctcg agcagcaggc cgagcgcctc gagctcctcg accaccttgt
     6241 cgcgcgcggg cacgcggtcg agcccggcga cgcccgccgg catcggcacg ctctccaggg
     6301 tgacgccgtc ggcggtgtag cgctcggcca ccgcgggcac ggcgccttcg agggtgagca
     6361 cgacgatggt gtcgagcttg tggcgctggc ccaccgcgta gtcgttgaag tcgtgcgccg
     6421 gcgtgacctt gacgcagccg gtgccgaact cgcggtcgac atagtcgtcg gcgatgatcg
     6481 ggatgtggcg gccggtgagc ggcagctcga cggtcttgcc gatgagatgg gcgtagcgct
     6541 cgtcctcggg atgcaccatc accgcgacgt cgccgagcag ggtctcgggg cgggtggtgg
     6601 cgaccgtgag gccgcgcagc tcgccgatgg ggccgtcgga gaacggatac aggatgtggt
     6661 agagcttgcc gtcctcttcc tcggacacca cctcgagatc ggacaccgcg gtgccgagct
     6721 tggggtccca gttcaccagg cgcttgccgc ggtagatcag gccctcgttg tagaggcgca
     6781 cgaaggtctc ggtgaccgtg cgcgacaagc cctcgtccat cgtgaagcgc tcgcgcttcc
     6841 agtccgggct ggtgcccagc cggcgcatct ggcgggtgat ggtgccgccg gagtactcct
     6901 tccactccca caccttctcc aggaagcgct cgcggccgag atcgtggcgg ctgacgcctt
     6961 gggcgtcgag ctggcgctcg acgacgatct gcgtggcgat gccggcgtgg tcggtgcccg
     7021 gctgccacag cgtgttgtcg ccacgcatgc ggtggtagcg cgtgagcgcg tccatgatcg
     7081 tctggttgaa gccgtgcccc atgtgcagcg tgccggtgac gttgggcggc ggcagcagga
     7141 tgcagaaggc ggcggggttc gacttgtcga gaccggcgtc gaagtagccg cgggattccc
     7201 attccgggta ccagcgacgt tcgatgtctg cgggctcgaa gctcttggcc agttccatgg
     7261 tgttctacgc gcgtgagggc aaagcgcgga ttatagcgga tgcggcgcag gcgccccggt
     7321 gcgagcgcgc cgcggggctt tgcctgcgtc cgcttccgcg ccttgggtta tgggattgcg
     7381 caggtctcct gcagcagcgc cgccaggcgc gaaagcggcc gcaggggtgg cagacaggtt
     7441 ggtgcgcggg ccgccggttc gtggcggccg ccgctcctaa cgcccgggcg ggtggtcggg
     7501 cctgcggtct tcgaacaggc tgctgacccg tgccgagatc tcggggagca gggtggcgcg
     7561 caggtgggcg agggcttcgt cctggatgcg ctcgccgagg cggtcgagct cgcgggcgat
     7621 gatctgcggc agctcgcgtg cggcccactc gtcgatctcg cgcgcaatcg cggtgtcgag
     7681 ctcgaccagg cgctcggcga gttgctgctc ggctgccgca acgctcggtg gtggtggagg
     7741 ggatggtgcg gcaggctgag cgaaggtgtc gacgggctcg ggcggcgcgg cgggcgcgcg
     7801 tgcatgcgag acttcgcccg gcgcaaggct gcgcacgaag gcgggctgcg ctgctgcggc
     7861 agccgcgagc gaggactcgg tcggctggaa aatctccgtc ggcaggtcga gatcgtccac
     7921 cacctcggtg aggatcggca ggtcgtcgtc gtcgaaggcc tgcatggccg caccgcttgg
     7981 cgtcgcgtgg actggttcgg cggcgtcgcg gtcggttgag cgctgcgtac ctggggagga
     8041 gggcgccgtg tcgccgcggt ggcggcgcag cagggcatcg gcctggccga gcaggtcgtc
     8101 ggcacgctcc agttcgtcgt cgtcggggaa gtcctgccag tctttcacag cgccaccctg
     8161 cgttcggcgt cgaaggcctt cagttcgtag ccgcgctggc ggtaagcggc ccagcgctgg
     8221 cgggcggcgt gcacctcggc ggcgtcacga ccgacgatct cgaccaccat gcggaagccg
     8281 tccgcctcgg cggggaggtc gtcggcgagg ttgaacagca tgtcggcgtg cggccacggg
     8341 cagggctctc ccgcggcgcc gagcaccacc ggggtctcgg ccgcgagtgt cgaggcgacg
     8401 ccgacgtggg gcacgaaatc gagcggcacc gcagtccaca gcacttggtc gagccgacgc
     8461 agctgcgtcg cgtcggtgca gcgcagggcg accttgcggc cgcgtgcgta ggcgcccgcg
     8521 accagctcgt gcgcgagcgc gagccggtct gcggtgttgt ggtagaactg cacgcgcggc
     8581 gccatggcgg gcggcgaccg atcctcaggc cgcatgggcg cgggcgcgcc cgatcaggaa
     8641 gctgctcagc agcggcaccg gccgcccggt ggcgcccttg gcgtcgcccg acacccaggc
     8701 ggtgccggcg atgtcgaggt gggcccactt gtaggccttg gtgaagcgcg ccaggaagca
     8761 ggccgcggtg atggtgccgg cgtagcggcc gccgatgttg cccatgtcgg cgaagttgct
     8821 cttgagcagc tcctggtatt cgtcccacag cggcagctgc caggcgcggt cgcccgattc
     8881 ggtgccgcgc ttcaggatct cggcggcgag ctcgtcgtcg ttggcgagca gcccgctggg
     8941 gattttgccg agcgcgacca cgcaggcgcc ggtgagcgtg gcgatgtcga tcacgcactc
     9001 gggcttgaag cgctcggcgt aggtcagcgc gtcgcacagg atcaggcggc cctcggcgtc
     9061 ggtgttgagc acctcgatgg tctggcccga catcgaggtc accacgtcgc cgggcttggt
     9121 ggcgccgccg ccgggcatgt tctcggtggt gggaaccagg ccgacgaggt tgatcggcag
     9181 gcccatctgt gcgaccgcct tgaaggtgcc gagcacgctc gccgcgccgc acatgtcgaa
     9241 cttcatctcg tccatctcgg cggcgggctt gagcgagatg ccgccggtgt cgaaggtgat
     9301 gcccttgccg accagcacga cgggcttcgc cttggccttg ccgcccttgt actgcatgac
     9361 gatgaacttg ggcggctggt gcgagccgcg cgccaccgac aggaaggagc ccataccgag
     9421 cttctccatg tcctcgcgct ccagcacctc cacctcgaac ttgtactgct tgccgagggc
     9481 ctcggcagtc tcggccagat gcgtcggcgt gcagatgttg cccggcaggt tgccaaggtc
     9541 cttggccagt gccatgccgg cggcgatcgc atggccctgc attgcggcgg tgtcgagctc
     9601 ggcgccgagc tcgcagctca ccagcaggct gagcttcttc gcgccgcgtt ccttcttcgc
     9661 cttcttgtcg gacttgagca cgtcgaagcg gtaggcaccg tcggcgagca tgcgcgtggc
     9721 ctgctgcagc cgccaggcgg cgtcgcggcc cggcagctcg atgtcggcga gtgccacgac
     9781 cgcgtccttc gccggtccgc cggagatcgc cttcgcggcg gcggcgaggg cgtcgcggaa
     9841 ggccttgtcg ccgaactcgt cgtgcttgcc caggctcacc agcagcacgc gctcggcgtg
     9901 cacgccgggc aggtcgtgca ccagcacgct ggcgccggcc ttctcgtcga ggtcgccgcg
     9961 cttgatcagg gtcgccaggc ggccttcggc ggcgccgtcg gccgctgcgg agagggcggg
    10021 gaggcggccg tcggcaaagg cgccgagcac gagcaggccg gtcttgagct tcgccgggct
    10081 gccggtcttt atggtaaatt ccatgcgctt ttccttgttt ggatgcctgg tttcgattgc
    10141 cgaagattat ggcgcgttcg caaccggggc gtcaaaaacg cttccgatcg acatcggccg
    10201 tggcgcgcag cccggcccca tcccggtatc gacccccgcc cgatgatctt ccggcgtgcc
    10261 ctgcaacggg aattcgcgca gacggccgcc gcggttttcg tggcgctgtt cgcgatcctg
    10321 atctccaccg tgctcatccg cctgctcggc caggcggccg gcggtcgcgt gccgcccgac
    10381 gcggtgatgg cgctgatcgg cttcggcgcg ctcgcgcagc tgcccacggt gctcaccctc
    10441 acgctcttca tcgcggtgct ggtctcgctc tcgcgcagct atcgcgactc cgagatggtg
    10501 gtgtggttcg cttccggcgt gccgctcacc gcctggatcc ggccggtgct cctgttcgcg
    10561 ctgcccattg ccgtggtggc tggtgcgggc tcgatctacc tgtcgccatg ggcgcaacaa
    10621 aagagcggcg aataccgcga gcgtctggaa agccgcgacg acacccatcg cgtcgccccg
    10681 ggcgtgttcc gtgaatcgac cagcgcgcag cgggtgttct tcgtcgaggt cggcgccggc
    10741 gaggatggcc gggtgcgcaa tgtcttcgtc agcgagcaga cgcgcaacgg gcagctcgtg
    10801 gtgatcgcct cggcggaggg ttatctgcgc agcgacgagg agggccggcg cttcatcgtg
    10861 ctcgagaagg gccggcgcta tgacggcacc cctggcacgc ccgagtaccg ggtgatggag
    10921 ttcgagcgct acgaggtgca ggtcgaacag aagcaggtgg ccgggcagca ggcccgcatc
    10981 cgcgcgctgc ccaccgcggt gctgctcgcc cagcccgagg cacgcggcct cggtgaactg
    11041 gtcgggcgct tcggcgtacc cctcgtcgcg ctgctgctgg cgctgatggc gatcccgctg
    11101 tccttcgtca atccgcgcgc cgggcgcgcc aacaacatgc tggtggcgct gctggtgtac
    11161 ctcgtctata gcaatgcgat ctcggtgttc cagtcctggg tggcgcaggg caagctgccc
    11221 ttcgcggccg gcctgctgtt gccgcatgtg gtggtgctgg ctgcgctcgc gctgatgttc
    11281 cacaagcgcc tggcgatctc gccgttctgg cggaggcgcg catgagcccg gtgctgctgc
    11341 gttacctcgc acgcgagatc ttcgccgcca gcgcgctggt gttggtcgcg ttcctcggcc
    11401 tgttcgcctt cttcgacttc atcaacgaac tcgaggacgt tggcaagggc ggctacacgc
    11461 tctaccaggc cctcgtttat gtggcgctga ccctgcctgc gcgggtctac gagctgatgc
    11521 cgatcgcggt gctgatcggc acgctttacg cgctggcgac gctggcgaag aactccgaga
    11581 tcaccgtgat gcgcgcctcg ggcatgtcga acggcctgct gatgagcgtg ctcggcctga
    11641 ttggcggtgt gttcgcggtg ctgatcttcc tgatcggcga atacgtcgcg ccgccggcgg
    11701 agaccgcagc cgaggagtgg aagctcaccg ccacccaggc caccgtgtcg cagcaactgc
    11761 gttcgggttt gtgggtgaag gatggccgcc tggtcatcaa cgtgcgcacg ctcatgcctg
    11821 accgcacgat gcgcggcgcg cgcgtctacg ccttcgacga cgactatgcg ctcgaatcga
    11881 tcgccgaggc ggcgaccggc gtcttcgatg gcagcgggga gtggaaactg ctcgatgtgc
    11941 agcgcacgcg tttccatggc gaccgcaccg aggtcgaacg cctggccgag atccgctggc
    12001 gctcggagct gacccccgag gtgctcggcg tgctgatggt gtcgcccgag catatgccct
    12061 tcggtcgcct gtggacctac atcaaccacc tgcgcgacaa caaccagaac gccgaccgct
    12121 tcgagatcgc gctgtggaag aagctgatct atcccttcac cgcgctggtg atgatggcgc
    12181 tggcgatgcc cttcggcttc atccacgacc gcatgggcgg cgcgagcgcg cgcatcttca
    12241 tgggggtgat gctgggcgtg ggcttccacc tgctcaacgg cctgttctcc aacctcggca
    12301 tgatcaacgc ctggccgccc ttcatggccg cgctgacccc cagcctgatc ttcctcgtcg
    12361 ccgcgttctg gctcatgcac cgcgtcgagc ggcgctgagc cggggctgct gggcgggcgg
    12421 gttgcgctcg tgcgagcggg cctgcccgcg aacggacgtt cgacgaggct cgattcgcgg
    12481 gcaaacccgc tcccgcacga ggaaatcggt gaacaaaaaa acgggcccga aggcccgttc
    12541 cgatgaagcg accgccggag cgatcagcct tcctgttgct gctgggcggc acgcttggca
    12601 gcggcagcct tgtagtccag cttttccttg atgcgcgccg acttgcccga gcgctggcgc
    12661 aggtagtaca gcttggcgcg acgcacgtca ccacgacgct tgacctcgac gccggcgacc
    12721 agcggcgagt aggtctggaa ggtacgctcg acaccttcgc ccgaggagat cttgcggacg
    12781 atgaaggaag agttcaggcc gcggttgcgc ttggcgatga ccacgccctc gtaggcctgc
    12841 agacgctcgc ggttgccttc cttgaccttc acctggacga tcacggtgtc gccgggaccg
    12901 aactcgggga tggtcttgcc ctgcgagacg cgggccattt cttcctgttc gagttgctga
    12961 agcaggttca ttgcagatac tccatcgatg ttatcggcct tcgcctcttg cgtcggcctg
    13021 gccgcagagc aggtcgcaac ctgatgcgcg ccgtttgtga aaggacgctc agccgcgctg
    13081 gggttccagt gcgtcctgcg tcccggcttg ctcctgcctg aactcgtcaa gcagtttcaa
    13141 ttcggtcttg ctcaacggcc gcgccccgag caggtcgggc ctgcgcagcc aggtgcggcc
    13201 gagggactgc ttcagccgcc agcggcggat cgccgcgtgg ttgcccgaca gcagcacatc
    13261 gggcacccgt tcgtcttcgt acagctccgg ccgcgtgtag tgcggacagt ccagcagccc
    13321 gtcggcgaag gaatcctcct gcgccgagcc ggcggtgttc agcgcgccgg gcagctggcg
    13381 cacgatcgca tcgagcagca ccatcgccgg cagctcgccg cccgacagca cgaagtcgcc
    13441 gagcgacagt tcctcgtcga cctcgcggtc gatcaggcgc tggtccacgc cctcgtagcg
    13501 cccgcacagc aacaccagcg cgggctcggc ggccagctcc agcaccacct cctgcgccag
    13561 cctgcgccct tgcggggaca ggtagatcac ccgcccgctg cggccgagcg ccgcttgctg
    13621 tgccgcgcgt gcggcgcgga tcgcctgcgt cagcggctcg gccagcatca ccatgccggg
    13681 gccgccgccg taggggcggt cgtccaccgt gcgatgcgga tcgctggtga agtcgcgcgg
    13741 gttgtgaaac tccagcgcgt acagcccgcg atcgatcgcc cgccgggtga tgccgctgcc
    13801 ggtgagcgcg gcgaacatct cggggaagag ggtgaccacg tcgtatcgac gcggcccgcc
    13861 cgcaacgccc ggagggctcg cctgctgcgt ctcgccttgc gggatgtgcg gattcaccgg
    13921 ccttccacag tcccgtgtta ccagtctttc tgccaggcga cccggatgcg ccgggtggcc
    13981 aggtcgacgt cgagcacgta ggccgcgacg aaggggatca ggcgttcgac cgcctcgtcg
    14041 ccattgcctt cacgtacctg caggacgtcg tgcgcgccgg tcgagatcag ccctgcgacc
    14101 gtgccgaacg cctcgcccgc ctcgttttcc accgccaggc cgacgaggtc gccccagtag
    14161 tactcgccct cggcaggctt gggcagggcc tcgcgcggcg cgccgatgta gaagccgtcg
    14221 acggcctcgg ccgcgccacg gtcggccacc tcggcaagcg cggccaccaa ccccttgccg
    14281 tgcgcgcgac aggcggtcag cgtgtattgc ttccacgcct cggcgggcgc gtcgtcgtcg
    14341 ctgcacagcc accagtgcga catcttccgc cacgaggcgg ggtcgtcacc gaaggggtgg
    14401 atcttgatcc agccctgaac gccaaaaggg gcgacgatgc gccccagtac gatcatgcgc
    14461 cgctcagccg ctgatcgacg tcggtcaggc cgcggccgtg gcagcctgct tgaccaggcg
    14521 ggcgacggtg ggcgacagct gggcgccgtt ctgctgccag taggcgagac gctcggcgtt
    14581 gatcacgaga cccttttcgg cgcccgaggc gatcgggttg tagaagccga cgcgctcgat
    14641 gaagcgaccg tcgcggcggt tgcgcgaatc ggcaacgacc atgttgaaga acgggcgctt
    14701 tttggcgcca ccacgggcaa ggcgaatgac gaccatctgg atgttcctga tcggtggatg
    14761 cgaaaaaccg cggattatag gggagtcgcg cgctgcggac aaggctttct tgtccgtcgc
    14821 cagcgcttcc gcccctctcg tccgatcccg tgcagcatgg gcgcgcggtg ttgcggcgtg
    14881 cttgcggcgg aaggggatag aatgcaggca ccttcagtct ttcgccgggg accatggaag
    14941 cgccgtcgac accgtccgat gcagagcagt cgctgctccg ctggctcgag agcgagccgg
    15001 cggacgccgt cgaggacgat ctcgctgcgc tgcgcgcgca cctgctcgac gccttcggtg
    15061 gcgctggccc gggcacgaac gaggtagtgc tgcgtgcgct tgccgagcgc atcggcgaca
    15121 tcggcgcgcg tctgcgcccc ctgatgattg cacgtcagct cccggtggag gttgcgctct
    15181 tcgaggccaa cgagcagttg tgcgcgctcg ccctggacgt cgccgcagcg atcgcgggtc
    15241 tcgcggggag tggcagtgtt gcgcgttccg gggccgaggc cgagctttgc gagtacgcga
    15301 tcggcctggt caccgaggtg ttcgcgctct gtgagttggc cgccgcgccg cccccggccg
    15361 ggacctggcg gctggcacac gactttgccg cccgccgccg gatcgccacg gcggcccccg
    15421 acgatccctt gcgctgcgcc tacgtgcgcc tgctcgcggt cgcggtcgcg cagcccgaag
    15481 ggcttaccgg gcgagagatc gcctggctgt acgacttcct cgatgcgcgt gtgctcagtg
    15541 cggcggtcct cgtgcacggc gtgggcgaca tgagcgcgtc ggcgtggtgg atcgacctcg
    15601 gcgcggatct cgcgccacag gcggtctcgc gccggccggc gccctccggg tcgatgctgg
    15661 gcggcgaggt atggagcttc aatccccgtc cgatggcgca gaagctgggc gagtgcatcg
    15721 aatgggtgac cgcccgcatg accgcggcgg agcttgccgg gatgcagggc gaagtcgagc
    15781 cgctgacggc cgaggaggat ctctttccgc ctggcctgtc gcccctcgag acggtggcct
    15841 tgctgcgtcg cctgcgcagc tactggatgg cggcgccggt gcgcgggcag ccgcggcgcc
    15901 agcatcaata cgtggtccag gtggggatcg gcctgcaggc ggtgtgggac ctcggtggcg
    15961 ggggtacggc cgaggtcgac tcgctccagg agtggatggt cctcaacgag agcccgggag
    16021 ggctcgcgat catgagcgtg gccggggttc gcggcgagat cgaggcgggg ggcgcgctcg
    16081 ccttgcgccg tgagcagggg caggcctggt ccgtgtgcat cgtgcgctgg gtgcgcagtg
    16141 atctgccggg gcaggtggag gtcgggctgc agatcatcgg gcagtccttc cacccggtga
    16201 tggtcgggtt ccgcgggcgc gcggtgcagc agctctctcc tgcgctggcc ttgccgatca
    16261 tggagccctt gcgccgtcat ccggcaatgc tcgcggtcgc aggcacctac gcctcgcgcc
    16321 gcttcgtatt cgtgcgcgag acgcagacgg tctatgtcgc gcaggcgcgt gcgctcgggc
    16381 tcgacctgca gacgccgagc gtcgaacttt tccagtacga gatcgatccc tatccgatct
    16441 gagcgccgcg cctgcgattg ccctgggggt gcgcggtcgg ccggcggtga cggcgcgata
    16501 taatccggcc tctttctgga gcaggcatcc gatgcacgaa atcctcgtcc tctactacag
    16561 ccaccgcggt tcggtgcgcg cgctcgccga gcacatcgcc gccggcatcc atcaggtgcc
    16621 gggcgcggtg gcgcgggtgc gtacggtgcc gcgggtgtct accgtgtgcg aggcggtcga
    16681 ggacgacatc ccggcctcgg ggccgcccta cgtcgaggtg gccgacctgg aggagtgcgt
    16741 cggcctggca ctcggcagcc cgacgcgctt cggcaacatg gcggcgccga tgaagtactt
    16801 cctcgacggc ctcgcgggcg cctggctcaa cggcgccctc gagggcaagc cgggctgcgt
    16861 gttcacgtcc tcgtccagcc tccacggtgg gcaggagagc acgctgctgt cgatgatgct
    16921 gccgctcttc catcacggca tgctggtgct ggggctgccg ttctccgagc cggcgctcgg
    16981 cgagacgcgc acgggcggta cgccctacgg cgcgagccat gtgtccggga gcgagggcga
    17041 tgccgcgctc agtgccgagg agatcgcgct tgcgcaggcg caaggccgac gcctggccga
    17101 ggtggcgatg cgcctggcgg gggcgcgatg aacgcgcgcg cgctgagcct ggtgtcgagc
    17161 gccgcgctgc tggcgctgat cgtgctgtgc gtggtgtggg agggctggct cgccccgctg
    17221 cgtccgggcg gctcgtggat gatgctgaag gcgctgccgc tgctgccggc ggtgttcggt
    17281 gtgctgcgcg gccggcgcta cacctcgcag tggctgtcga tgctgtcgct gctgtatttc
    17341 accgagggcg tgctgcgcgc ctccgacccc ggcctcaccg gcgtgttcgc cttgaccgag
    17401 gttttcctcg cagtagtgct gttcaccagc acgatgctgc acgcgcgcgc gacggcgccg
    17461 tcgcgcgcgc aggnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnccccatg
    17581 taggagcggc ggcagccgcg aacccgtcgg tcaccgcggt gcccgcggag cgttgcgcca
    17641 ccggtccgcg accgccgccg gcattcgcgc cttccggcgc tcctgcagga ggcgcctggt
    17701 gcccctcaca cctgcgggtt gagccgctcc gcgcccgcgt gcagcttgtt gagcgcgttc
    17761 aggtaggcct tggccgaggc gacgatgatg tcggtgtcgg cgccctggcc gtccatcacg
    17821 cggccgtcgc gcgacaggcg cacggtgacc tcgccctggg cgtcggtgcc gctggtgatc
    17881 gcgttcaccg agtacagcag cagctcgctg ccggtggtgg cgaccgtctc gatcgccttg
    17941 aaggcggcgt ccaccgggcc ggagccgttg gcgcgcgcct gcttctcggc gccgccgatc
    18001 gacagggtga tttcggccac cggggtctcg ccggtctcgg agtggaagcg ggtcgacacc
    18061 aggcggtact gctcgggcgc cggcgtgact gcctcgtcgc gcatcagcgc ggtgaggtcc
    18121 tcgtcgaaga tctccgactt gcggtcggcg agctccttga agcgcgcgaa ggcctggttg
    18181 aggtgctcct cgctctcgat ctcgatgccg agctcctgca ggcgggcgcg gaaggcgttg
    18241 cgcccggaga gcttgccgag caccagcttg ttggcacccc agccgacgtc ctcggcgcgc
    18301 atgatctcgt aggtctcgcg gtgcttgagc acgccgtcct gatggatgcc cgactcgtgc
    18361 gcgaaggcat tggcaccgac gatggccttg ttgggctgca ccgggtagcc ggtgatctgc
    18421 gacaccagct tggaggccgg cacgatctgc gtggtgtcga tgccggtctc gaccgggaag
    18481 atgtcggcgc gggttcgcac cgccatgacg atctcctcga gcgaggcatt gccggcgcgc
    18541 tcgccgaggc cgttgatcgt gcattcgacc tggcgcgcac ccgcacgcac cgcggccagc
    18601 gagttggcca cggccagccc gaggtcgttg tggcaatgca ccgaccacac caccctgtcg
    18661 gagttgggca cgcgctcgat cagcgtgccc acggtggtgg cgaactgctc gggcacgttg
    18721 tagcccacgg tgtcgggcac gttgatggtc ttcgcgccgg cgtcgatcac ggcctcgaag
    18781 atgcgcacca ggaagtcgat ctcggagcgg ccggcgtcct cggcggagaa ctcgacgtcg
    18841 tcggtgtact cgcgcgccca accgatcgcc ttgaccgcct gcgcgacgac ctcgtcgggc
    18901 gtcatgcgca gcttcttctc catgtggatc gggctggtgg cgatgaaggt gtggatgcgg
    18961 ccgcgcgccg ccgggcggat ggcctcgccg gcgcggcgga tgtcgtgctc gttggcgcgc
    19021 gccagcgtac agacggtgga ctccttgatc gcctcggcga tcgagcgcac cgcctcgaag
    19081 tcgccgttgg aggcggcggc gaagccggcc tcgatgacgt ccacgcgcat acgctcgagc
    19141 tggcgggcga tgcgcagctt ctcgtcacgg gtcatcgacg cgcccgggct ctgctcgccg
    19201 tcgcgcaagg tggtgtcgaa gatgatcagc ttgtctttca tggcttgctc ccggggtcgg
    19261 atgaggcgcc ctcgacgggc gcggcggcgg tgtcgccggc ttgttcggta tgggtggggg
    19321 aggccgggct ggcaggttcg gcccggtgcg agcggcgtcg gcgccagcgc agcgcggcga
    19381 cgatgtagcc ggagccggcg taggcgagga agagggcgaa caggatgccg ggcgggtagc
    19441 tggagatcag cgcgaaggcg agcaccagcg cgatcagcac gatgaagggt acgctcttgc
    19501 gcaggttgat gctcttgccg ctccagaaca gcacgttgct gaccatggag acgccggcga
    19561 agatggtcag caccgcggcg taccagcgca ggtcgtcgcc ggcgaagccg ttgtcgatgc
    19621 ccacccacac catgccggcg accagcgccg ccgccgccgg gctgggcagg ccctggaagt
    19681 agcgcttgtc gaccacgtcg atgttggtgt tgaagcgcgc caggcgcagc gcggcgccgg
    19741 cgcagtagat gaaggcggcg acccagccga gcttgccgag gtcctgcagc gcccactcgt
    19801 acatgaccag cgccggtgcg gcgccgaagg agaccatgtc ggagagcgag tcgtattcgg
    19861 ccccgaactc gctctgggtg ttggtcaggc gggcgatacg gccgtcgagg ccgtcgagca
    19921 ccatggcgac gaagatggcc accgcggcgt actcgaagcg ctggttcatc gcctgcacga
    19981 tcgcatagaa gccggcgaac agcgcggcgg tggtgaacag gttcggcagg atgtagatgc
    20041 cgcggcggcg cttgtcgggc aagggcagcg gggcgtgttc gatatcgggc accttgggtg
    20101 tcgcctccgt ggaatccaga atcgtcattt tagcgcacgc acacgcgcgc ccggctgcaa
    20161 aagcgctcgc cgccgtaccg cagccgcgca aggcacatgg ccgccgccgc aacgaaaaag
    20221 gccggcaccg cgactgcggt accggccctt ggaccgaacg ccggggcgat cagttcttcg
    20281 acttgtcgac cagggccttg gccttgatcc agggcatcat gtcgcgcagc tggccaccga
    20341 ccttctcgat ctggtggtcg gcgttgaggc ggcggtaggc ggtcatgctc gggtagttgg
    20401 tcttgccctc gaggatgaac atcttcgcgt actcgccggt ctggatgcgc ttcagcgcgt
    20461 tgcgcatggc ggcgcgcgac tgctcgttga tgacctcggg cccggtcacg tactcgccgt
    20521 actcggcgtt gttcgagatc gagtagttca tgttggcgat gccgccctcg tacatcaggt
    20581 cgacgatcag cttgagctcg tgcaggcact cgaagtaggc catctcgggc gcgtagccgg
    20641 cttcaaccag cgtctcgaag cccatcttga ccagctcgac ggcgccgccg cacagcacgg
    20701 cctgctcgcc gaagaggtcg gtctcggtct cttcgcggaa gttggtctcg atcacgccgc
    20761 ccttggtgcc gccgttggca gcggagtagg acagcgcgat gtccttggcc ttgcccgagc
    20821 ggtcctggta gatcgcgatc agggtcggca cgccgccccc gcgcaggtac tcggagcgca
    20881 cggtgtggcc ggggcccttg ggggcgacca tgatcacgtc gaggtcggcg cgcggaacga
    20941 tctggttgta gtgcacgttg aagccgtggg cgaaggcgag caccgcgcct ttcttgatgt
    21001 tcggctcgat gtcgtcgcgg tagacctgcg gcgcggtctc gtccggcagc aggatcatga
    21061 cgaggtcggc ggccttgacg gcttcgccga tttccttgac ggccaggccg gcggcctcgg
    21121 ccttggccca ggagctgccg tccttgcgca ggccgacggt gacattcacg ccggagtcgc
    21181 gcaggttctg ggcgtgggcg tggccctgcg agccgtagcc gacgatggtg acctgcttgc
    21241 ccttgatcag cgagaggtcg gcgtccttgt cgtagtaaac cttcatgtct ttcctttggt
    21301 tcgatgtgga gcgggggagg ggggagctca gaccttcagc acgcggtcgc cgcggccgat
    21361 gccgcagacg cccgagcgca cggtctcgag gatcagtgcc gggtcgatcg cgccgatgaa
    21421 ggcgtcgagc ttgccctggt tgccggtcag ctcgacgacg taggaggcgt cggtgacgtc
    21481 gatgatgcgg gcgcggaaga tgtcggcggt gcgcttgatc tcctcgcggt ccttgccggt
    21541 ggcgcgcacc ttgacgagca tgagctcgcg ctcgatgtgg gcggcctcgg agatgtcgac
    21601 gaccttgacg acctcgacca gcttgttcag ctgcttggtg atctgctcga tgatctcgtc
    21661 cgagccggtg gtgacgatgg tcatccgcga catcgagaag tcctcggtcg gggccacggt
    21721 gagcgattcg atgttgtagc cgcgcgccga gaacaggccg gacacgcgcg acagcgcgcc
    21781 ggattcgttt tcgatcagga gggaaatgac gtgacgcatg gtgatggatt ccggattcgg
    21841 tgggaggcga tcagaggtct tcggccgaca ggatcatctc ggtgagaccc ttcccgccct
    21901 gcaccatcgg atagacgttc tcggtctggt cgatctggaa gtcgaggaac acgagctcgt
    21961 tcctgtgggt tgtgaacgcc tcccgcagcg cgccctcgac gtcggcggga cggtcgacgc
    22021 ggatgccgac gtgaccgtag gcctcggcca gcctggcgaa gtcgggcagc gagtccatgt
    22081 aggactcgga gtaacggccg ccgtggaaga gctcctgcca ctggcgcacc atgcccaggt
    22141 agcggttgtt caggttgcag atcttgatcg gcaggcggaa ctgcttgcag gtcgacagct
    22201 cctggatgtt catctggatc gaggcctcgc cggtcacgca ggccaccggc acgtcggggt
    22261 tggcgagctt ggcgcccatg gcgtagggca tgcccacgcc catcgtgccc aggccgcccg
    22321 agttgagcca gcgccgcggc ttgtcgaagc cgtagtactg cgccgcccac atctggtgct
    22381 ggccgacgtc cgaggtgatg atggcgtcgc cgccggtgac ttcccacagc ttctggatca
    22441 cgaactgcgg cttgatgatc tcgtccgagt tcttgtagac catgcacttg cggtcgcgcc
    22501 actgctcgat ctgtttccac cacgcggcca gcgcctcggg gttgggacgc gcctcgccgg
    22561 attcgagctg gcggatcatc tcctcgagca cttccttgac gtcgccgacg atcggagtat
    22621 cgacgcgcac gcgcttggag atcgacgacg ggtcgatgtc cacatggatg atcttgcgcg
    22681 gctcctcggc gaagtgcgcc gggttgccga tcacgcggtc gtcgaagcgg gcgccgacgg
    22741 cgagcagcac gtcggagtag tgcatcgcca tgttggcctc gaaggtgccg tgcatgcccg
    22801 gcatgccgag gaactggcgg tcgctcgagg ggtagccgcc gaggcccatc agggtgttgg
    22861 tgatcgggta gccgaggagc cgggtgagct tggtgagcgg ttcggccgcg ttcgacagca
    22921 ccacgccgcc gccggtgtag atcatcgggc gcttggcctc gaggagcagc tgcaccgcct
    22981 tcttgatctg ccccgagtgg cccttggtca ccgggttgta cgagcgcatc gagatctctt
    23041 tcggatactc gtactcgcag cgctgcatcg acacgtcctt cgggatgtcg accagcaccg
    23101 ggccggggcg gccggtgcgg gcgaggtgga aggccttctt catcgtcgcg gcgatgtcgc
    23161 gcacgtcctt gacgaggaag ttgtgcttga cgcaggggcg ggtgatgccg acggtgtcga
    23221 cttcctggaa cgcgtcctgg ccgatcgcgg cgaccggcac ctggccggaa atgatcacca
    23281 tcgggatcga gtcgcagtag gcggtggcga tgccggtgac ggcgttggtg gcgccggggc
    23341 cggaggtcac catggcgacg ccgaccttct cggtgctgcg cgcgaagccg tcggcggcgt
    23401 gcaccgcggc ctgctcgtgg cgcaccagca cgtggcggac cttgtcctgc tggaagagcg
    23461 cgtcgtacag gaagaggacc gcgccgcccg ggtaaccgaa gacatactcg accttttctt
    23521 cctgcaggca cctgattaca atttcggctc cggacagcac catcgcgaac tcgctctatt
    23581 ggggttttga ataaacgcag aacgttaccg gccggtcgcg gtttggtcaa ggctgcaggc
    23641 ggtcccggat gaggcgggca ggcgcgcgca gcgaacctgg tcgcgctctt gacgttgtcc
    23701 tgcgcctgcc gctgccacag gctttcagcc tgccgccgcg ccggcggtcg ctcgacgctg
    23761 tccctgctcc ctgttttccc gccgcaacgc ccattttcgt gccgcaccga tgcggccgcc
    23821 tggatcgact catgacgcgt agcaagagcc gggccggcaa ggccgctcct gacggggtgc
    23881 ctgccgccca gcccccggca cgagatgccc tcaaccgcaa ggacacggcc ggtgcgaccg
    23941 ccagcgaccg ccccagcgcg gagctcgccg ggctgcgtcg ccgcctcgcc tcgatgctct
    24001 acgagtcgat gctgctgctc ggcgtgctcg cgctcacctt cctcgtgccc tacctgatgc
    24061 tcggcatcgc cgccgagttc gccccgccgg gctggctgct ctggctgcat gtgttcggcg
    24121 tgctcggggt ctatttcgtg tggtactggc gacgtggcgg gcagaccctg gcgatgcaga
    24181 cctggcggct gaagatcgtc accgctgccg acggccgcat cgcctcgctc gggcgctgct
    24241 ggctgcgcta cgcgctcgcc tggtcttcgg tgctgctcgg cggcatcggc ctggcgtggg
    24301 cgctggtcga tcgcgatcgc cagttcctcc acgaccgcct cgccggtacc tgcatcgtgc
    24361 tgctgcccac ccccgcgaag ggctgagcgg ccactggccg tccggcccgt gcactccggg
    24421 aggccgacgg tcccgggggg cggatcggtt accattcgat cacaggcact gcttgcgctc
    24481 cgcgcgcccc gtaccccggg tgcctcgcgg agtgacacga ggatcgaacg atggccgcga
    24541 tgctggccca cgggccctac gccgaattcg ccgtgctgct gatcatctcc gcgctggccg
    24601 gggcgatcgc ggtgcgcctg cgccagccgg tgctgatcgc ctacatcgtg gtcggcatcc
    24661 tggtcgggcc ggcggtgttc ggtatcgtca ccgcgcacga tcaggtcgcg ctcctcgccg
    24721 agatcggcgt caccgtgctg ctcttcgtgg tcggcctcaa gctcgacctc caccatatcc
    24781 gccacatcgg cccggtcgcg ctcgccaccg gcctcggcca gctcggcttc accatcgtgt
    24841 tcggcttcct catcatcgtg ctgatgggca agagcctgat ggaggcgctc tacgtcgcgg
    24901 tggcgctgac cttctcgagc acgatcatcg tggtcaagct gctgtcggac aagcgcgagc
    24961 tcgactcact gcacgggcgc atcgcggtgg gcttcctgat cgtgcaggac gtcgccgtgg
    25021 tgctggcgat gatgaccatg agcgcgctgc gcggcgccgg cgaggatgcc gtgctggccg
    25081 tggcgggaca gctcgcgctg cgcctggtgg gggccaccgc gctgatgttc gtgctcatgc
    25141 gctacgtcct gccctggctg gtgcacgcga tggcgcgctc gcaggagctg ctgctgatct
    25201 tcgccatcgc ctggggcacc gggctcgccg cgctcggcga ggtcgccggc ttcagcaagg
    25261 aggcgggcgc cttcatggcc gggttctcgc tcgcctccac cgcctaccgc gaggcgatga
    25321 acgcgcgcct gaccggcatc cgcgacttca tgctgctgtt cttcttcgtg gatctcggcg
    25381 ccaagctcga tttctccacc ctcggcggcg agctgtggcc ggcagtgatc ctctccttgt
    25441 tcgtgctcat cggcaatccg ctgatcgtga tggcgatcat gggctacatg ggctatcgca
    25501 agcgcaccgg cttcatggcc ggcctcaccg tggcgcagat cagcgagttc tccatcgtgt
    25561 tcgtggcgat gggaatcacc ctcggccaca tcggcgtcga ggcgctcggc ctcaccacgc
    25621 tggtcgggct ggtcaccatc atgatgtcca cctacctgat cctgtactcg cagccgctct
    25681 acgagcgcct cgcgcccgtg ctcggcgtgt tcgagcgcaa gcgccccttc cgcgagctcg
    25741 cggtcgagcg ccagggcagg gcggcgggcc agcccgacat cgtggtgttc ggcctcggcc
    25801 gctacggtgc gcgcctgatg cgccagctgc gccaggccgg catcgaggtg ctcggcgtcg
    25861 acttcgaccc cgagatcgtc cgccagctgc gccgccagcg cctgccggtg cgcttcggcg
    25921 acggcgagga ccccggcttc ctcgaatccc tgccgctcgc cgacgcgcgc tgggtggtga
    25981 ccaccttccc gcagtgggac tccaaccgcg ccttcctgca cgcgctcggc gaggccggct
    26041 tcaagggccg catcgccggc gtggtgcgcg acgacatcca cggcgccgcg ctcggcgccg
    26101 caggggtgga gcgcgtgctc aaccccttca acgacgcggc cgactacgcg gcgcgcacct
    26161 tcgcggcgga gatcgcctac gaggacgccc accgcgcgga tatcgccgac gctgccggca
    26221 cgcaagccgc tgcgccggcg cggccgcccg cgaggcccca ggagactgaa cgatgaaccc
    26281 gatccgcact gtcgtcgccc ccaccgacct ctccgcgctc gcccgccacg ccgtggtgcg
    26341 cgcctgcctg ctcgccgccg agctcggcgc gcgcctgtcg ctgcagcatg tggtcaatgc
    26401 cggcgcgctc gacaccctgc gtcacctgct cgatgccgac gccgccggcg tgcaggagaa
    26461 gctgctcgcg gaggtgcgcg gcgaggtcga ggcgctcgcc gcagagatgc acaggcgcca
    26521 cggagtcgtg cccgagcagc agctggcggt aggcagtgtg ctcggcgaga tcgtcgctca
    26581 cgccgaggcg gtcgacgccg acctgctggt gatgggtgcg cgcggcgccg gcttcatgcg
    26641 cgagctgctg atcggctcca ccaccgagcg cgtgctgcgc aagtccgtgc ggcccatgct
    26701 ggtggtcaag cagatcgccc acgaacccta ccgccgcgtg ctcgtgccgg tggatttctc
    26761 cgcgcgcgca ctcgaggcct tgcagttcgc gcagtgcgtg gcgccgcagg ccgagttcgt
    26821 gttgctgcac gccttcgagg tgcccttcga gggcaagctg cgctacgccg gcgtggagga
    26881 gaatgcgctg tcctctctgc gcgtcaatgc ccgccgcgag gcgggtgcgc agatgaaaga
    26941 gctggtcgcg tgcgccggcc tcgacgagaa ccgcgtgcgc cgcatcgtgg tccacggcga
    27001 ggccaccacg cagatcctcg agcaggagca ggagcaggac tgcgacctga tcgtgatcgg
    27061 caagcgcggc cacggcctgc tcggcgagat gctgctcggc agcgtcacca agcacgtgct
    27121 cgcgcgctcg accgccgacg tgctggtctg cgaccgcaag ccggactgag gcgcgccggg
    27181 cgagttccgg cggcgctcgt gccggcccgc ttcggcccgg gcgcatcttt gcgccaggta
    27241 aagcctgccc accctgtgcg gctcgcccgc cagggcgtac actcgcgccc ttgccgcgcc
    27301 cgcgaggcgc cgatggagaa ctcataatga aaaccgaaca tgccccgacg atccagcgcg
    27361 ccgactaccg gccgctggcg tggacggtcg agaccgtcga ccttcacttc cgcctcgacc
    27421 ccgaggccac gctggtcacc aaccgcatgt gctgcgtgcg caaccgcgac gccgccgacg
    27481 gcccgatccg gctgtggggc gaggtgctcg agcgcgtgtc gctgaccgtg gacggccagc
    27541 ccccgcaagg gctgcacgaa gacggcggcg ccatcgacat cgacgccgcg ggcgatcgcg
    27601 tggtggtcga ggtcgtcacc cgggtggatc cgcgcgccaa caccacgctg tcgggcctct
    27661 acctgtcgaa cggcggcttc ttcacccagt gcgaggccga gggcttccgc cgcatcacct
    27721 gcttccccga ccgccccgac gtgatggcac gctacacggt cacgctcgaa gccgaccgtg
    27781 acgcctgccc ggtgctgctc tccaacggca acctcgtcga cgagggcctg ctgcccgagg
    27841 ggcgccacta cgcgaagtgg gaggatccct tccccaagcc ctcgtacctg ttcgcgctgg
    27901 tcgcagcgaa gctggtcgcg ctcgagcgca ccgtgaccac gatgtcgggc cgcgaggtgc
    27961 tgctgcaggt gtgggtggag gagggcaacc tcgaccgcgt cgagcacgcg atggattcgc
    28021 tggtgcactc gatgcgctgg gacgaggaga ccttcggcct ggagctcgac ctcgaccgct
    28081 tcatgatcgt cgcggtggcc gacttcaaca tgggcgcgat ggagaacaag gggctgaaca
    28141 tcttcaacac caagttcatc ctcgccaagc ccgacaccgc caccgacctc gactacgaga
    28201 acgtcgagag cgtggtcgcg cacgagtact tccacaactg gacgggcaac cgcgtcacct
    28261 gccgcgactg gttccagctc accctcaagg aaggcctcac cgtcttccgc gaccagcagt
    28321 tctccgccga catgctcgcg cgcgcggccg gccccgaggg cgcggcttcg gcgcgcgcgg
    28381 tcaagcgcat cgacgacgtg cgcgtgctgc gcgcggcgca gttcccggag gacggcgggc
    28441 cgatggcgca cccgatccgc cccgacagct accaggagat caacaacttc tacaccgcca
    28501 cggtgtacga gaagggcgcc gaggtcatcc gcatgctgca caccctcctg gggcaggagg
    28561 gcttccgcaa cggcatggac ctctacttca gctacttcga cggccaggcg gtgacctgcg
    28621 acgactttgt cgaggtcatg tccgaggcca acaacggctt cgacctcgac cagttcatgc
    28681 gctggtacga acaggccggc acgccgcggg tgaaggcgag cggggtgtgg aacgccgccg
    28741 acgacagcta cacgctgacg ctggcgcaat cgaccccggc cacgcccggc cagcacgtca
    28801 agcagccgct ggtgatcccg gtcgcggtcg gcctcatcgg cgcggacggg cgcgatctgc
    28861 cgctgcagct cgagggcgag gcccaagcgg gtgcctgcac gcgcgtgctc aagctcaccg
    28921 aggacgagca gaccttccgc ttcgtcggcg tcgctgccga gccggtgccc tcgctgctgc
    28981 gcggcttctc ggcgccggtg atcctggagc tcgacgagga tgacgcgcgc ctcgccttcc
    29041 gcatggcgca cgacgccgac ccctgcaacc gctgggacgc cgcgcagcgc tacgccgagc
    29101 gcgtggtgct ggacctcgcc gcggatgccg gcgccgaggt gccggatgcc ttcgtcgccg
    29161 ccttccgcac gctgctgaac gacggcgcgc tcgaccccgc cttccgcgcc caggcgctcg
    29221 cgctgccggg cgaggcctac ctgctcgagc gcatgtcgcc cgccgacccc gccgcgctgc
    29281 gcagtgcgct ggtgcgcatg atgcgcgcgc ttggcgccac gctcaccgcc gactggctgg
    29341 aggtggtcga gcgcctgcag gtacgcggcg agtatcgcta ccacccgggt gacgccggcc
    29401 gccgtgcgct ggtgaacctc gccctgcgct acctcgccgc cgccggcgtg gccgagggcc
    29461 tggcactggc cgaggcgcgc ttcgccgccg ccaccaacat gaccgagcgc ttcggcgcgc
    29521 tcgccgcgct ggtgcagagc acgagcccgg cgcgcgccgc cgcgctgcag gccttccacg
    29581 accgccatcg cggcgatgcg ctggtgctcg acaagtggtt cgcgctgcag gccggcgcct
    29641 ggcgctgggg tgaggaggcc gagccggcgc ttgcgcgcgt gcgggtgctg ctcagcgacc
    29701 ccgccttcag tctgtcgaac ccgaacaagg tctacgcgct gctgggcacc ttcttccgcg
    29761 ccaacccggg cgagttccac gccgccgacg gcagcggcca tgccttctgg gccgagcagg
    29821 tgatcgcgct cgacgcccgc aacccgcagg tcgcggcgcg cgtggcgcgg gcgctggaga
    29881 actggcgcca cttcaccccc gccctgcagg ccagcatccg cccgcagctc gaacgcgtgc
    29941 tcgccgcgcc gggcctgtcc gcggacgtgg ccgagatcgt cggcaaggcg ttgggggcgt
    30001 gaggcgtgag gggtaaggtg tgaggtgagc ggcggcgcgg gcctggttcc tgcgcgcttc
    30061 tcgtccgcgc aaacgacgac gccggatccg actcccgtcg gctccggcgt ctgcatttct
    30121 ggcgacggtg tcgccgcgag gctcactccg cggcgaggtc gccggcgatg tagctctcga
    30181 gctgcttgat ggtcttttcg tgctgggtga cgatggactt caccatgtcg ccgatggtga
    30241 cgatgccgat caccttgcct tcctcgacca ccgggatgtg gcggaagcgc ttggcggtca
    30301 tcgtcgccat cacgtcgtcg gcggtacccg tcaggctgac cgtgtagggg ttgggcgtca
    30361 tcaggtcgcc gaccttgacg tcgcgcgaca ccaggccctt gagcacgact ttgcgggcgt
    30421 agtcgcgctc ggtgaagatc ccgaccagct tgtcgccgtc ggtgaccagc acgcagccga
    30481 tgtcgaactg cgccatcagc gacagcgcgt cgaagaccga gtcggtcggg cgcaccgcat
    30541 ggaaggtgcc gcctttcgcc tcgaggatct gttttaccgt cgtcatcatc tttccactcc
    30601 cccttcttcg ttgaaatgcg cgccgcaggt cgcggccggg cctttattcg cgggttttac
    30661 ggtttttaac cagatccgcc cgccgatgca agcgcggccg catccggatc cagcctcccg
    30721 cttcagattt ccaggttgtc gatcagccgg gtgcggccga gtttcgctgc cgcgagcacg
    30781 acgagcgcct cgtccgtctg cgtcggcggc tgcaggtcga ggcggcggcg cacggcgata
    30841 tagtcgggtg cccagcccgc ggcaccgagt tcggccatcg cgtcggcttc cagctgcgcg
    30901 aagtcccgtc cgcccgcacg caccgcgtcg cggatgcccg cgagcaggcg atgcagcagc
    30961 ggcgcacgcg cacgctcgtc cgcgctcagg tagccgttgc gcgaggacag cgcgagcccg
    31021 tccacggcac gcaccgtctc cccggctacg acctcgatcg gcatcgccag ttcgcgcacc
    31081 atgttcgaca gcaccatgag ctgctggtag tccttcttgc cgaacagcgc cacctcgggt
    31141 tgcacgatgt tgagcagctt catgaccacg gtggcgaccc cgcggaagtg gccggcacgg
    31201 aactcgccct cgaggatgga cacctgctcg gcgggcggat cgacgtggta gcgctgcggc
    31261 tgtgggtaca tgaccgactc gtcgggcgcg aacaggtgct cgaccccggc ggcggcgagc
    31321 ttctcgcagt cggcggcgaa ggtgcgcggg tagcgctcga agtcctcgcc ggcgccgaac
    31381 tgcaggcggt tgacgaagat gctggcgacc acgcagccgg cgtgatcgcg cgcctggcgc
    31441 atgagggcga tgtggccctc gtgcaggttg cccatggtgg ggacgaaggc gacgcggccg
    31501 gcgcctgcgc gcgcggcgcg caggctgtcg atggtttcgt ggatctgcat gcgggcttcc
    31561 tcgcgtacgc gacgcgggtt cagtaacagt gctcggcggc cgggaagctg ccgtccttga
    31621 cggtggcgac gtagcgcgcg accgcctcct cgatgctcgc cgcgccgtcc atgaagttgc
    31681 gcacgaagcg cgcggtcttg ccggggaaga caccgagcag gtcgtgcaga accagcacct
    31741 ggccgtcgca tgcagcgccg gcgccgatgc cgatggtggc catgctggac aggctggcag
    31801 tgatctcgcc ggcgagcgcg gcgggcacca tctccatcac catcagcgcc gcgccggcct
    31861 gctcgagcgc cagggcgtcg gccttgaggc gcgcggcacc ttcctcgctg cgcccctgca
    31921 cgcggtagcc gccgagctgg tgcaccgcct gcggggtgag gccgatgtgc gcgcacaccg
    31981 gcacgccgcg ctcgaccagg aagcgcacgg tctcggccat gaacgcgccg ccttcgagct
    32041 tgaccatctg cgcccccgcg gccatcaggc gcgcggcgtt gcgcatggcc tgctcgcggt
    32101 tctcgtggta gctgccgaag ggcatgtcgg tgacgacgaa ggggcgcgcc ccggcgcgcg
    32161 ccacgcattc ggtgtgatag gccatctgct cgagggtcac cggcagggtg gacttctgcc
    32221 cctgcagcac gttgccaagc gagtcgccga tcaggatgga gtcgaccccg gcacgcccga
    32281 ggagggcggc gaagctcgca tcataggcgg tgagcatcgc gatcttgcgg ccttcggcgc
    32341 gcatcttgcc gagttcgaag agggtgacgg gcttctggtc ctggagatag ctcattcatc
    32401 gctcctgttg ggaggcggca gtgtcggcca aactggtgcg ttgcacaagc ctcgtggccc
    32461 tcgccgcgcg acggcagggc gagctcagtc cgcgtagccg aagaactcgc ggtagctgcg
    32521 catctcgcgc aggcgctcga gcagcagctc gaagtcctcg tcgcggtcga ccgggttgag
    32581 cttgccggca tccacgatga acagcggggc ggcatcgtac tggtagaaat accgggtata
    32641 gcgctcggcg acctgctcga ggtagagctc ggtgatgcgg cgctcggcgt ccagcccgcg
    32701 cttgcggatg cgctccatca gggtgtccgg gcgcgcctgc aggtagatca ccagatcggg
    32761 gcggggggcg ttgcgcggct gcaggccgtc atgcacgcgg cgatacagcg cgagttcgtc
    32821 cggcgacagg ttctgctccg cgaacaggtg gtccttgtcg aacaggaagt cggccaccac
    32881 gcgacgctcg ccctcgatcg ggccgagtgc ggcgagctgg tcgatgcgct ggaacaggaa
    32941 ggagagctgg gttgccaggc cccagcgctc ggactgctgg tagaagcggc caaggaaagg
    33001 gttgagctcg gcctgctcga acaccgcctc ggcctggaga cggtcggcca ggcggcgggc
    33061 gagggaggtc ttgccggcgc cgatcggacc ttcgacgacg atgtagcggg ccttgtcgag
    33121 catgctgggc tgtctttgcg gcgagcgcgc gtcagttgcg gaagatgaaa tacaccgcgc
    33181 cgagcataca caaggccgcc cacaggtagt caagcttgag cggctgcttc atgtagagca
    33241 cgacgaaggg tacgaagacc agcagggtga tgacctcctg catgatcttg agctgggcga
    33301 ggctgagcgt ggtggcgccg atgcggttgg cgggcacctg cagcaggtat tcgaagagcg
    33361 cgatccccca gctcaccagc gctgccacgt accaggcctt ggtctgcatg ttcttcaggt
    33421 ggccatacca cgcgaaggtc atgaagacgt tggaggcggt gagcagcagc gcggtctgca
    33481 cccaaacggg aatcgagctg acggactgga tccaggcggc catgggcgga cggagggcgg
    33541 gtcaggggcg cggcgaggcg gcgggcggcg gcacgcgttc gatcgcctgg ccggcgagcg
    33601 caggcagcag cgccgcgatc gcgccgcggc cggggatgct cgccgcgggg tcgatctcgg
    33661 ccagcggcag cagcgcgaag gcgcgctcgt gcatgcgcgg atgcggcacc tgcagcccgg
    33721 gttcgtcgat caccgcgtcg ccgtgcagga gcaggtcgag gtccatcgtg cgcggcgcca
    33781 tcggaaagtc gcggcggcgg ccggcgtcgt gctcgatggc gagcagggcc tcgagcagcg
    33841 gacgcggcgc gagcgtggtg tcgagcgcga tcacggcgtt gaagtagtcg ggctggccgg
    33901 cgacgcccac cggggcgctg cggtacagcg aggagcttgc cacgacgcgg gtgccgggca
    33961 gcgcgtcgag gcgctgcagg gcgtcggcga aggcggcagc cgggtcgccg aggttggcgc
    34021 cgaaggcgac gtatgcgcgg atcaagcggg cgcgctcagg acggatcggc aagggtagct
    34081 tctgccgccg cggcgttctc gccggcaggc ttgcgcttgc ggcggcggcg cttcttcgcc
    34141 gcgggcgcgg cgtcgggcgg tgcctggcgc agcagcgcct cgcgccggtc gggcccggca
    34201 tgggcgaagt cgtcccacca gtcgacgatc tccatcggga tctcgccggc ctgcgcgcgc
    34261 aggcgcagga agtcccagcc ggcgcggtag cgcggctgct cgatgacgcg atagggggcc
    34321 ttgccggcgc gcttgtcgaa gcgcggctgc agcgcccaga tgtccttgat gtcgccggcg
    34381 atgcggcgag tgatggcgag cttgccggcc tgcgcgtcga gcacctcgtc catggcctcg
    34441 aagagcgcgg gctggctgtg gtcgccggcg gccttcttgt tctcccaggt cttcagcacc
    34501 tcgtgccaga gcagggtgga gaacaggaag ccgggcgaca ccgacttgtc ctggcgcacg
    34561 cgctcgtcgg tgttctccaa tgacagggtg acgaagcgct cgcccatcgg ctgctcgagg
    34621 atcacgtcca gcagcggcag caggccgtgg tgcaggccct ctccacgcag ttgctgcagg
    34681 cacttcagcg agtggccgga gaacagcagc ttgagcatct cgtcgaagag ccgcgccgcc
    34741 ggcacgttct cgagcagcgg ccccatctcg cggatcggct ggcgcgccgc ggggtcgatg
    34801 gtgaggccga gcttggccgc caggcgcacc gcgcgcagca tgcgcaccgg gtcctcgcgg
    34861 tagcgcgtgc gcgggtcgcc gatcatgcgc agggtcttct gctggatgtc ggcgacgccg
    34921 tggtggtagt cgacgatggt ctcggtgccg gggtcgtagt acagcgcgtt gacggtgaag
    34981 tcgcgccgcg tggcgtcttc ctgctggctg ccgaagacgt tgtcgcgcag cacgcggccg
    35041 tgctcgtcgg tctcggcgct ctcggcgtcc tggctggcgc ggaaggtgga aacctcgatc
    35101 gtttccgggc cgctcatcac gtgcacgatc ttgaagcggc ggccgatgat gcgcgagcgg
    35161 cggaaggcgg cgcgcacctc ttcgggcgtg gcgctggtgg cgacgtcgta gtccttgggc
    35221 ggctggccga tcagcaggtc gcgcacggcg ccgccgacga cgaaggcctt gaagcccttc
    35281 tcctgcaaga ccgcgcacac cttgcgcgcg gccggcgaca gctgctcgcg gcggatgccg
    35341 tggcgttcga cggggatgat ggcgggttcg tggcgtgcgg gggtggccgg gcgcttgaag
    35401 accttgcgca gcagcttgcg gatcatcggg aaaggagtcg tgcttgcata agcgggcaat
    35461 gataaccgat cgaatcgtcc gcacgctgcg cgaacgcggc ggtcgcgcaa caggcgcggg
    35521 tcgcggtgcc caccgccgcc ttcgcgcctg ccggcgctcc tacatgaacc gccgcgcgtt
    35581 ccggacgcgc tcctgcgcaa actgccgcgt gtcccggccg cgctgtagga gctgcnnnnn
    35641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    35701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnctgcc ggcgctccta cataaaccgc
    35761 cgcgcgcccc ggacgcgctc ctgcgcaaac tgccgcgtgt cccggccgcg ctgtaggagc
    35821 tgcggcagct gcgaacacgg cggtcggatc atcgacgcgc gtcgctctcg gtcggcgcca
    35881 ttttcgcgcc tgccggcgct cctacataaa ccgccgcgcg ccccggacgc gctcctgcgc
    35941 aaaccgtcgt gcgtccccgc cgcgcttccg gggggtgtag gagcggcggg agccgcgaag
    36001 cgtcagcgca gcgagatcac cggccagccg gcggactcgg cgtgggcgcg cagggtgggg
    36061 tcggggtcga ccgcgaccgg gtcggtgacg cgctgcatca gcggcaggtc gttgtgcgag
    36121 tcgctgtaga accagctgtg ctcgaagctg cccaggtgca ggccgagcga ctccagccag
    36181 gcgtcgacgc gctcgatctt gcccgccttg aaggccggcg taccgcgcgg cttgccggtg
    36241 aaggcgccgt cctgttgcgc ggggatggtc gccaccacgt gcgggatgcc gaactcgcgc
    36301 acgatcggac cggtgacgaa ggcgttggtg gcggtgacca ccgcgaccag ggcgccgctg
    36361 tcgagatgct cgcgcaccag cgtgcgcgcc ttgggggtga tcatcggacg gatcgatcgc
    36421 gtcatgaact cgctgtgcca ggcgtcgagc tgttcgcgcg ggtggcgggc gaggggggcg
    36481 agctggaagt cgaggaaggc gaagatgtcg agcgtgcccg ccttgtactg ctcgtagaac
    36541 tcgatgttct tcgcctcctg cacttcgcgg tcgagtacgc ccttgccgat gaggaactgc
    36601 gcccaggcga agtcggagtc gccggcgagc agggtgttgt cgaggtcgaa gaggacgaga
    36661 ttcacgatcg ggctccgcaa gatggttcgg gtgggtgagg attcgaagga ggcggtgcgc
    36721 gtgtcgggcg ccgccttcgc gggttcagat ttccagcccc tgctggatca tgtcgcgcag
    36781 cagcggcagg gtgatcgggc gcttgtgctc gagcgaggcg cggtcgagcg cgtcgagcac
    36841 ctcgcgcagg ctggagagct cgcggcggcc gtggcggagc aggaagtcca ccacctcgtc
    36901 ggccaggcgc aggccgcgcc gcgccgccag ggtggcgagg atctcggcgc gcgcggcgtc
    36961 gtcgaggggc tgcacctggt agatcaggct ctgcccgatg cgggtgcgca ggtcctcgcg
    37021 cagcgccagg ccgagcgggg cggcggggcc gcacagcagc agcgactggc cgttgccgcg
    37081 ggcgcggttg aaggcgttga agagcgcgat ctgcgcggcg gcgccgagct ggtcgacgtc
    37141 gtcgatcgcg agcagcgcgt ccggcgtttc gggcaggtcg tcctcgacgg tcgcggcggc
    37201 gaggaggtgg gccggccggc cggcagtgcg tgcggcgtcg accgcggcac gcagcaggtg
    37261 gctgcgtccg ctgccgggcg cgccccacag gtagatgtgg cgcgcgggca gctgcgccgc
    37321 catggcgggc gaggtcagca gcgacacggt ggccaccagc tcggcgttgg cgccggcgac
    37381 gaagttctcg agcgtgggcg gggcgtcggg gcggatgtcg aggacgagct gcttcatggg
    37441 cgctcgagct cgcgtgcgat caccggtcgc ggctgcgtgc cgagatacac cgggctggca
    37501 agccaggcct ggcgcacctc gcgcaggccc accagcagcg cggcgcccac cggcagcgcg
    37561 accagcacgc cgacgaagcc gaagagctgg ccgaaggcca tcagcgcgaa gatcaccgcg
    37621 agcgggtgca ggccgatgcg ctcgcccacc agatagggcg tgagcaggaa gctctcgacc
    37681 aactgaccga gcgcatacac gatcgccacg ccgatcagcg gcggccagcc ctgcgcctgc
    37741 agcagggcgg cgacgatggc gaggatcagc ccgccgccga agccgacata ggggatgaac
    37801 accagcaggc cggtgagcac gcccaccggc agccagaagt tgagcccggc cagccacagc
    37861 ccggcgctgt agaacaccgc cagcagcagc atcaccgaca gctggccgcg caggaactcg
    37921 gacatcaccg agtcgatctc ggcgaggatg cgggtggtgg tggccaccca gggccgcggc
    37981 acgatgcgct cgagctcgtc gaggatgcgc ggccactcct gcagcaggta gaacatcacc
    38041 agcgggatga gcaggacgtt ggcggcgaag cccagcaccg ccat
//
LOCUS       DAOTIN010000023        36780 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_1239_length_36780_cov_8.949707, whole genome shotgun sequence.
ACCESSION   DAOTIN010000023 DAOTIN010000000
VERSION     DAOTIN010000023.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 36780)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 36780)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36780
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1239_length_36780_cov_8.949707"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..319
                     /locus_tag="P5537_05580"
     CDS             <1..319
                     /locus_tag="P5537_05580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77547.1"
                     /translation="IRAQMVGLMAGPAAEQIFRGEAVRLCPAGEFDEVRQAEDLSWLL
                     AARDAFADAVALTAHTLSQPEVWAAVESVAHELERAGTLTRGLRGLLPAALPDWPPGG
                     SAA"
     gene            complement(556..1776)
                     /locus_tag="P5537_05585"
     CDS             complement(556..1776)
                     /locus_tag="P5537_05585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HRV77548.1"
                     /translation="MSLPLRSLLRILPRAPGGDLGGGGRPRSGLSLPPIEDIARETLP
                     PQDAEPAEDAELAPLADAFVRDALAAGEEALQRQREAVDTMGIELQRQAAWRSEMLQA
                     PIRKLAHQGDEGGPVAQALLALRDKMQDLDPARQKLSGEGLSRALSFIPGVGKPMQRY
                     FQKYEKAQDALDAIIRDLQSGADMLRRDNLTLADDQQSLRAILAQLERQVELGRMIDR
                     RLAREAASAGLPAPRRAFVEEELLFPLRQRIVDLQQQVAVSQQGVLALEVVIRNNREL
                     VRGVDRAINVTVSALNVAVTVALGLANQRLVLDRVAALNETTSALIAGTAQALRTQGV
                     DIQTRASSSMLDMGQLEQAFGDVLGAIDDLSRYRREALPKLDAQIDRLAGLAHQGQEA
                     IRRMDEGRRADPQP"
     gene            complement(1793..2722)
                     /locus_tag="P5537_05590"
     CDS             complement(1793..2722)
                     /locus_tag="P5537_05590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinic acid a,c-diamide synthase"
                     /protein_id="HRV77549.1"
                     /translation="MFEFLQGIAFGLLVSFVPWFMAGMYDPRLVVPEELASRWQVILR
                     YAVAMPSVATLLLLTSLWGGFGASLGGWLAGLAAAPAALFLERRWRRWREARAGKERA
                     AARERARTELARGRRERDLLTLDPDFVPADADAVVMQLWEVKRELVGLRRPDLAVQAD
                     RLFTRYHRALDVLDEKFDRREVTYERARGLVGEVGSGAAAGLGAMVALVQGSVGLDAD
                     FVRERLEREAARLGGTEREALQRRLALADETERRLGEIAAGNEAALTALDHVAVAVAR
                     IDTGRGQPAGATEQALQELRRFAERAGLYGRQQ"
     gene            complement(3077..3709)
                     /locus_tag="P5537_05595"
     CDS             complement(3077..3709)
                     /locus_tag="P5537_05595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HRV77550.1"
                     /translation="MKLTSQSFTDGARIPGEFAFCIPAAEGHVCLGGNRNPQLSWSEV
                     PAGTKSFVLICHDPDVPSKGDDVNQEGRTVPASLPRVDFFHWVVVDLPAELRAIEAGH
                     FSAEVTPGGKPGPEAALGARHGVNDYTAWFASDESMKGDYHGYDGPCPPWNDEIVHHY
                     VFTLYALDVARCAVEGRFTGADARAAIAGHVLAEVKLTGTYSLNPALAAR"
     gene            complement(3754..5595)
                     /gene="sppA"
                     /locus_tag="P5537_05600"
     CDS             complement(3754..5595)
                     /gene="sppA"
                     /locus_tag="P5537_05600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HRV77551.1"
                     /translation="MIRGLFRFLLNVLRMFVRALDLVVRGVFYALLIFGLGVLVSFFF
                     HPEPEVPAGSALVLRPVGTIVEQAELEPPLALLRAGGAPAGQLRLADLVDAVRKARDD
                     ARIAALVIETDELVGGGFSKLAELRAAIADFKTSGKPVLARGERFTQSQYYLASVADE
                     LHLSPDGFVLLRGLARYGSYFKDALDKLGVKVHVFRVGEYKSFSEPFTRSDMSDEDRE
                     ATRDLLDGLWRFMRDDIAASRKLAPAAVDAHVNDIRGALATAGGDAAKAALAAGLVDR
                     FSTRDEWRARLIEAVGTDHEGKDVRAIEVDAYLALAADDAQDAAGNVAVIVAQGTIVD
                     GAEPAGVVAGDTFARLIREAREDEDIKALVLRIDSPGGSAWASELIRRELQLTREAGK
                     PVIASMSSVAASGGYWIATGADEIWAAPSSVTGSIGIFGLFPEFSEPLRRLGIGVDGV
                     ATAPLAGALDPRRPLDPAAAEAMQLGIEHGYRRFLEVVAQARKMTVEEVDAVARGRVW
                     TGAAASSLGLVDKLGGLEDAIAAAAARAGLATHDVVWPAAGESLEQRLLRRLLRVGDD
                     LGIDLAGRAAPAAPLAVAAADVERAARELLRWNDPRHHYLHCLCDAP"
     gene            complement(5622..6365)
                     /gene="trmB"
                     /locus_tag="P5537_05605"
     CDS             complement(5622..6365)
                     /gene="trmB"
                     /locus_tag="P5537_05605"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine-N7-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HRV77552.1"
                     /translation="MSEVRDEVVAGVEIIGRDSPEHRFSSRSIRSFVLRQGRMSEAQQ
                     RYLDDMLPKVGIDYRAAPLDLDAAFGRKAPKILEIGFGMGETTAKIAAAMPDHDFLGI
                     EVHTPGVGALCKLIAEGNLTNLRIMQHDAVEVMRDMIADGALAGVHLFFPDPWRKKRH
                     FKRRIVQPDFVALIAQKLAPGGYFHCATDWEDYAHWMLEIISAEPLLQNTADGFAPRP
                     DYRPLTKFENRGLKLGHGVWDLVFRRRAG"
     gene            complement(6362..7147)
                     /locus_tag="P5537_05610"
     CDS             complement(6362..7147)
                     /locus_tag="P5537_05610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011237141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HRV77553.1"
                     /translation="MNDPLVIAGKAYHSRLLVGTGKYKDFAETREAIDASGAAIVTVA
                     IRRTNIGQNPGEPNLLDVLPPEKFTILPNTAGCYTADDAVRTLRLARELLDGHALVKL
                     EVLGDPKSLFPNMPETLKAAETLVKDGFDVMVYCADDPIQAKMLEDIGCCAIMPLASL
                     IGSGMGILNPWNLRLIIDNAKVPVLVDAGVGTASDAAIAMELGCDGVLMNTAIAAAGR
                     PVLMASAMKKAVEAGREAFLAGRMPRKFYSADPSSPTQGLIGS"
     gene            complement(7357..7560)
                     /gene="thiS"
                     /locus_tag="P5537_05615"
     CDS             complement(7357..7560)
                     /gene="thiS"
                     /locus_tag="P5537_05615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HRV77554.1"
                     /translation="MIQVILNGQPESLQPELSVLALLEARGLAGKRLAVERNGEIVPK
                     ARHAEVKLADGDKLEIVVAVGGG"
     gene            7755..8882
                     /locus_tag="P5537_05620"
     CDS             7755..8882
                     /locus_tag="P5537_05620"
                     /EC_number="2.3.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011237416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-acetyltransferase"
                     /protein_id="HRV77555.1"
                     /translation="MIAPQSVGVVVPQRAEFTTPLALRSGGTLDNYHLIYETYGTLNA
                     ERSNAVLVCHALSGSHHVAGTYADAPHNVGWWDNLIGPGKPLDTRKFFVIGVNNLGGC
                     YGSSGPNQTNPATGRLWGADFPFVTVEDWVESQARLADQLGIRRFAAIVGGSLGGMQA
                     MSWALQYPDRVGHVAVIAAAPKLTAQNIAFNEVARQAILTDPEFHGGHYYAYGVVPAR
                     GLKLARMVGHITYLSDDAMAEKFGRSLRHGRNTYSYDVEFEIESYLRYQGDKFAGFFD
                     ANTYLLTTKALDYFDPAFEYGGHLPAALARATADFLVVSFTTDWRFSPERSREIVYAL
                     LHNRRNVSYAEIDCPAGHDSFLLDEPRYHKLLSAWFDRIEV"
     gene            8963..9553
                     /gene="metW"
                     /locus_tag="P5537_05625"
     CDS             8963..9553
                     /gene="metW"
                     /locus_tag="P5537_05625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine biosynthesis protein MetW"
                     /protein_id="HRV77556.1"
                     /translation="MTAYRYDYEVITQWIEPGEKVLDLGCGDGELLRHLMDVRQVQGY
                     GVENDPDKLLGSVNNGVNVIQMDLEKGLVGLEDGFFDHVIMSLSLQAMHNTQGILAEM
                     LRVGREAVVSFPNFGYWRHRQSILNGRMPVSESLPHQWFNTPNVRFFTIADFDALCEL
                     NGIAVRERLAFDEGKLVLDEPNFLASVAVYRLGRNG"
     gene            9626..11314
                     /locus_tag="P5537_05630"
     CDS             9626..11314
                     /locus_tag="P5537_05630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77557.1"
                     /translation="MQENSEAVLVATGALPALILIAAALTLPVCLALLALYRRAVLRS
                     MALASPAAGSAASHPQETPSTPATPPTAMLRLEPRESGAAGARPALARMRRSLRAAGL
                     VHLLAGLAYALVLTTAWMQFTWEDGGFVPTRFLLVFACHAWPAVLAVGLVTAGTRRQR
                     LTLGLAYLLIVLALAAWALARNPALPALELARLWASINLPPTVLLLAFLHRRIRAVGP
                     LVLAFMLVAVIGAEAAVRLAGQSEATMRLAVGAGGALGLDGTQTFWALLLAGAAVAAL
                     LGRLVLKWLGRRHVARRSSDQILTLEAMWLLFAVVQSVGFAFEGLAWLAAGPLAFLAW
                     KLTTVAGFRLAGLGRAQGPAPGLLLLRVFALGARSERLFDAFGKRWLRIGHIDMIAGP
                     DLATTAVEPHEFLDFVGGRLSRAFVRDEADLARRHPARALGPDPDGRHRVNEFFCHDD
                     TWRPTMLCLARAADAVLMDLRGFSPQNEGCRYELQQLLDHVALERVVVLVGRDTDRGF
                     LERTLAALWQSSRAGSPNRDNPHPLLRMVEERGDDTAARLVEALLEAPPRAAAA"
     gene            complement(11328..11645)
                     /locus_tag="P5537_05635"
     CDS             complement(11328..11645)
                     /locus_tag="P5537_05635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77558.1"
                     /translation="MSHTVTVVFGGEREYEFPLRDADVASTTKEQARSWLAREFEDLE
                     CTPSNPMGKVLVLDMVLNVAKYGGEGRFEQAGEWARKYALHTAVALDRPAVRVDVSSF
                     VVG"
     gene            11781..13328
                     /locus_tag="P5537_05640"
     CDS             11781..13328
                     /locus_tag="P5537_05640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HRV77559.1"
                     /translation="MPARHLLSVPPRPALARAWRLSAILVLGFASGLPLALTGQAMQA
                     WLTVDGVDLATIGFFGLVGVPYTFKFLWAPLMDRFEPPWLGRRRGWLALTQLALAVLL
                     WWMASLSPTATPGLFAAAAVAIAFLSASQDVVVDAYRTDLLPEAERGLGASVHVFAYR
                     LAMILSGGIALIWAGQWASWPRVYETMALIMAACAVVSLLALPRVSAALKPLASDPRR
                     ELLGFAAMLAGVAAGYWIARQALILIGLDPNDANRWIQLLFVMAEIALALPLAGWAAR
                     RAGFETLNRSLSSYFAQQGAAAFLALIILYKLGDAFAGSLTTPFLIKGMGFSQEEVGI
                     ANKVIGIWLTILGAFIGGLIMTRLALYRSLLLFGVLQLVSNFGFYLLAELGKGAWGAV
                     MVPAFDWGFVALDAPAALDGLLLTVIAGENISGGMGTVAFVALLMGLCNQRFTATHYA
                     MLSAFAAVGRIYVSPLSGVLSQSIGWPAFFIFSIVVAVPGVVMVWWLRDALARLGRPQ
                     TDGAVDD"
     gene            13328..14098
                     /locus_tag="P5537_05645"
     CDS             13328..14098
                     /locus_tag="P5537_05645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HRV77560.1"
                     /translation="MAHTGTSARREFLAGCRDEAPLLLGVAPFGMIYGIAALAAGVPA
                     WLAQLASAIVFAGAAQLVIVQMLAAGAGFVPIALTSGLLNLRHVLYSASMADYVHHLP
                     RRWRLLLAYVLTDEAYAVAVLRYQQRHAGEADQAEQADSGTQAGGMDQVADLRHWYFL
                     GAGFTLWAGWQLSTAAGLLFGTTIPPEWELDFAVPLTFIALLTLLLRERAGQAAALVA
                     ALGALAFAALPYKLGLVAAIVLGLTAGAWTVRRLEHAR"
     gene            14095..14424
                     /locus_tag="P5537_05650"
     CDS             14095..14424
                     /locus_tag="P5537_05650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HRV77561.1"
                     /translation="MSTTTLLLLLALVGGLTYLYRYAMIGLFASRSLPAWLHALCRHI
                     APASFAALTASALFVAGGEVVFAFDTPRPWAALVAVLVAWRTRNVLATIGAGMAALYL
                     LKLLFPT"
     gene            14421..15143
                     /locus_tag="P5537_05655"
     CDS             14421..15143
                     /locus_tag="P5537_05655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HRV77562.1"
                     /translation="MTARILIDAARELSAAVDALPFAPPVTHVYNPLDYAWEVHRSYL
                     ERYGDGRRRVVFVGMNPGPFGMAQIGVPFGEIASARDWLGLEGPVGQPRVVNPKRPVE
                     GFACSRSEVSGQRLWGLFRARYGAPEAFFAEHFVANYCPLVFFEGGRNLTPDKLPMAE
                     QRPLLAACDAHLRTVVGALQPEWVIGIGNWAEKRSSEALAGLPGLKFGRVLHPSPASP
                     AANRGWAEAATKQLTELGIWPS"
     gene            complement(15250..16083)
                     /locus_tag="P5537_05660"
     CDS             complement(15250..16083)
                     /locus_tag="P5537_05660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HRV77563.1"
                     /translation="MKITPAPLLTLSNGVEMPRLGLGTWPMNDAEAAETVALALDMGY
                     RLIDTAENYENERGVGEGIRRSGVARGELFVTTKFNRKWHSVEGARQACEASLERLGL
                     DYIDLFLVHWPNPDQGRYVEAFEGLVKLQEAGLVRAIGTSNFKPAHLQQLFDRGLCPQ
                     VNQIHLDPWHARSDHIDVHKARGIVTESWSPLGRANAMLGDPAILDVARRHGRTPAQV
                     ILRWHTQLGYVPIPKSSNPQRLAENLDVFGFELSAEELAAISALDRPDPEMLDSDVFG
                     H"
     gene            complement(16328..17305)
                     /locus_tag="P5537_05665"
     CDS             complement(16328..17305)
                     /locus_tag="P5537_05665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerB family tellurite resistance protein"
                     /protein_id="HRV77564.1"
                     /translation="MNLNPQQARSLVAICLHAAFADGHQGAEERDQVRKVAESLGREA
                     EIDFIALYQDVLLGRLELEAAVAGLDEANLRQLAFELAVGVCEADGGLDDREKGFLER
                     LTGLLALSRPAAESFVHEAEAIGQAPAERPLAGLPGLGEDEPAAAPSTAAAAPDTAEL
                     DRTILNASILNGALELLPQSMASMAIIPLQLRLVYRIGQAHGYELDRGHIKDFLAAAG
                     VGMTGQYVEQFGRRLIGGLLGKVLGGAGRAVGSQATGSAFSFATTWAIGKVAVQYYGG
                     GRKLDTDALRQAFAGLFEQAKAMQERYAPEIAQRARTLDLKRLTDELRR"
     gene            17504..18151
                     /gene="can"
                     /locus_tag="P5537_05670"
     CDS             17504..18151
                     /gene="can"
                     /locus_tag="P5537_05670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004089 - carbonate dehydratase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbonate dehydratase"
                     /protein_id="HRV77565.1"
                     /translation="MSQSIEHLFANNKNWSERMHSEDPEFFTRLVNQQSPEYLWIGCS
                     DSRVPANQVIGLAPGEVFVHRNIANVVVHTDLNALSVIHYAVEILRVKHILIVGHYGC
                     GGVKAAMNDNKTGLTDNWLRHIQDVRDRHIDRLERFTDPSERADRLCELNAMHQVVNV
                     CQTSVLREAWQRGQGVTVHGWCYSLQDGLVRDLGVSSRTREEAVERYRDAVERIG"
     gene            18168..19073
                     /locus_tag="P5537_05675"
     CDS             18168..19073
                     /locus_tag="P5537_05675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HRV77566.1"
                     /translation="MGTRIGIDLGGTKIELVVLDAGGHERWRRRVPTPQGDYAGTLRA
                     IAALVEEAEHVTGAGARVGIGTPGSPSPRDGRIRNANSTCLNGQPLQHDLEALLRRPL
                     RLANDANCLAMSEAADGAGAGAGTVFAAILGTGVGGGIVVDGRLLVGANAVAGEWGHN
                     PLPLPDSGDLPLPVCYCGRAGCIETYLSGPGLAADHLRHGGEPVDAASIACRADAGER
                     ASQASLERYEARLARALASVINLLDPEVIVLGGGLSQVARLYENVPRLWPAHVFSDTV
                     STRLLPARHGDASGVRGAAWLWPAE"
     gene            complement(19495..21669)
                     /locus_tag="P5537_05680"
     CDS             complement(19495..21669)
                     /locus_tag="P5537_05680"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HRV77567.1"
                     /translation="MAIVRVALPVPLPQVFDYTAEDAGAEDVGRCVKVPFGRGERTGL
                     IVGLGDEAAVEAARLKAVLHIQRGVPPLPADWLELVGFVARYYHAPLGEVVALALPPG
                     LRRADGVSDEDEDPLLGITAEGREALAPGRRASRALTLLQALAEGAGPWRRSVIRARD
                     GGEAVGELLRRGWLEIVADPGARHEAGAQPLATPEQAAAVEVIVGAGMRFRPWLLHGV
                     TGSGKTEVYLRLAAHALAQGRQVLMLVPEIALTPQLEQRVAQRFAAANVVSLHSALAD
                     GARSRGFVQALSGRADIVLGTRLAVFAPLPRLGLILVDEEHDASYKQQEGVRYSARDV
                     AVWRARQRDVPVVLGSATPSLETWHHAKSERYALQTLSRRAVAATLPAVRCIDTRRIK
                     LDEGLSPALHAAIAQRLERGEQSLVFLNRRGYAPVLSCPSCGWVSRCPHCSANLVVHL
                     ADRRLRCHHCGCDGPIPHACPSCGNQDIQPFGRGTQRIEARLAELFPQARVLRVDRDA
                     ARTRSQWEKLLDTIAAGDADLLVGTQMMAKGHDFPRLTLVGVVGADASLHAADFRAPE
                     RLFQQLMQVGGRAGRGELPGEVLIQTEYPMHPLYLHLARHDFDAFARMALQERRAAGF
                     PPFTHQAMLRADAPALEDAVEFLRHARRLAEERAPEGLRLYDPVPMRMTRLARRERAQ
                     LLVESDQRGPLQAFLADWVAVLYRQRTARELRWQLDVDPLEV"
     gene            complement(22062..23132)
                     /gene="hemE"
                     /locus_tag="P5537_05685"
     CDS             complement(22062..23132)
                     /gene="hemE"
                     /locus_tag="P5537_05685"
                     /EC_number="4.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004853 - uroporphyrinogen decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase"
                     /protein_id="HRV77568.1"
                     /translation="MSRLKNDTFLRALLRQPTEYTPVWLMRQAGRYLPEYCETRKRAG
                     SFLQLCKSPAMACEVTLQPLARYDLDAAILFSDILTVPDAMGLGLYFAEGEGPRFERP
                     LRDEWEIRNLSAPDPHAELQYVMDAVAEIRRALDGSVPLIGFSGSPWTLACYMVEGGS
                     SDDYRKVKSLAYSRPDLMHHILDVTAQAVVKYLNAQIEAGAQAVMVFDSWGGVLSEAA
                     YKEFSLRYLEQVVAGLIRERDGQRVPSIVFTKGGGLWLESIAAIGCDAVGLDWTMDIG
                     RARRLVGDKVALQGNLDPNVLFAPPEAVATETRRVLDAFGNHPGHVFNLGHGISQYTP
                     PESVSVLVDTVHAHSRAIRAGA"
     gene            complement(23233..24708)
                     /locus_tag="P5537_05690"
     CDS             complement(23233..24708)
                     /locus_tag="P5537_05690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter TrkG"
                     /protein_id="HRV77569.1"
                     /translation="MSSDARTRAYYPALNALGLIIMIFGLLMSFPLIVSAVLGDGATL
                     AYDQGLFVTFVAGLLLWAATRSKRRDLRVHDGFLLVAATWVVLPLFGALPLLAYIPEL
                     GFTDAYFEAVSGLTATGATVLTGLEHLPISINLWRTFMHWVGGMGVIVLVVAILPLLG
                     IGGRQLYKAEVPTPMKDSSLTPRIAETAKGLWLTYVLLTVSCGFSLWWVGLEPWDAVI
                     HAFSVAGLGGFSNRDASLGHFDSVGVELVTIGFALLAGLNYATHYLALVRRSSAPYRR
                     DPEIPFYFGVLALSTGMLTVYLLAQGVFSDVGEALRYVAFHVVSISTSLGLATHDYTL
                     WPMFAQIWILFLGSFVACSGSTGGGIKMMRAMILYKQVFREIVRSLHPNAVRPVRMGR
                     NPVPENILHAVLGFSFMYMVSIVSLTLVLSAAGLELVTAFSAVVACLNNTGPGLGLVG
                     PASNYQALGDFHKWVLCFAMILGRLEIFTFLVVLTPTFWRR"
     gene            complement(24710..26113)
                     /gene="trkA"
                     /locus_tag="P5537_05695"
     CDS             complement(24710..26113)
                     /gene="trkA"
                     /locus_tag="P5537_05695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HRV77570.1"
                     /translation="MKIIILGAGQVGASVAENLVSEANDITLVDTSEEYLGALRERLE
                     IRTVCGNGASPRVLREAGADDADLLIAVTQSDQTNLCACRIAKALFNLPTRIARLRST
                     DYVDHPELLDDDNFAVDFSICPEQVVTDYIKRLIAFPEALQVLEFADGVVSLICVRAF
                     EGGPLVGHPLKALRFHLPNVEVRIAAIYRNGEPIMPEGDTIILPGDEVFCLAATVHIR
                     QVMRELRRSDRPMRRIMIAGGGNIGFRLAQSIEENHHVKILELNRTRAEMLASQLSHA
                     LVLRGDSTDEKLLETEGIDETDLFVALTNDEEDNIMSASLAKRMGARRTLALINRKSY
                     VDLVQGGPIDIAISPAHTSIGTLLAHVRRGDVVAVHSLRRGAAEALEIIAHGSSKDSK
                     VVGRPIEHIPLPRGASIGAVVRDERNEEGRVIRREVIIPHHDTVIREDDHVIVFCTNK
                     KLVQKVEKLFQVGFHFL"
     gene            complement(26355..27602)
                     /locus_tag="P5537_05700"
     CDS             complement(26355..27602)
                     /locus_tag="P5537_05700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004315384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV77571.1"
                     /translation="MAKILIVDDEIGIRELLSEILRDEGHDILLAENATAARAARNAV
                     RPDMVLLDIWMPDTDGITLLKEWAANGQLNMPVVMMSGHGTIDTAVEATRIGAIDYLE
                     KPIALQKLLAAVKRGLQRPQAPGVQSAPTLAAFHRSVPLRELRRRLEQIVGSSRVLLL
                     RVGAGSLAELVARSVQPANAPWLDLAAVTAPLDITQLQATQGGVLFVGELARLSRAQQ
                     KNLAFALDRLERYDLRLVVATERSLEALVGEGWEEGLLARLFEVSLAPPSIADVREDL
                     PELASQMLLHLVEAGEVPLRRFSTAALNQLRNLPWPGGYPELRAAVKSLALGTLEEEI
                     GAGEVRRLLPPDLGAGACGVSLDQPLREAREAFERMYFEHHLRLEGGNMTRLAEKTGL
                     ERTHLYRKLKQLGLQAGRRHEES"
     gene            complement(27612..29729)
                     /locus_tag="P5537_05705"
     CDS             complement(27612..29729)
                     /locus_tag="P5537_05705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HRV77572.1"
                     /translation="MKRVLLVVAAALAGISLFLLTSASSNTTLFATSYPWLLALNGGM
                     AVVLAALVGMQLHRLVREHREGQFGSRLKMRLVLMFALMGVVPGLVIYGVSLQFVVRS
                     IESWFDVRVDSALEGGIALGQNALDYLVSQVRDKSDDMVLELEGAGQGAGTRLNRLRE
                     QAGISSATILAPGGQVLATAAESGRTLLPDLPGTAELRQARQSRHFHSVIAEPDGRLV
                     IRVLTPIPLRTLAGEANLLMLQQPVPESFGRNAEAVQEAYREYQQLTLGRSGLKRIYT
                     VTLSLTLLLALLGALAVAVLIARRLAQPLLILAEGTQAVAQGDFSPRQALPANDELGV
                     LTQSFNRMTRQLQEARGAADRNRAEVEAARAYLESVLANLSTGVLAFSADGHLRAANH
                     GALQILEDDLAGFEDIPLEAWPRQAELGQALREGFTANEGDWQKQMELPLKDRPPRTL
                     LIHGSRLPASTGGGLVVVFDDISSLIAAQRTAAWGEVARRLAHEIKNPLTPIQLSAER
                     LAFKLADRLDDSGREMLERATGTIVNQVEAMKNLVNAFRDYARLPAPQLAPLDLNGLI
                     REVLHLYESAAVQIRTELGSTLPPVQGDATQIRQVIHNMLQNAQDALAAQEEGEIAVI
                     TRRDGESALLLFRDNGPGFPTEVLSRAFEPYFTTKSRGTGLGLAMVKKIVDEHGGEVR
                     LSNREGGGAEVRIRLRLAENKEA"
     gene            complement(29726..30325)
                     /locus_tag="P5537_05710"
     CDS             complement(29726..30325)
                     /locus_tag="P5537_05710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4390 domain-containing protein"
                     /protein_id="HRV77573.1"
                     /translation="MTASITRSSASGPERAVRFVVGVLFALFALLAHAESVIRSAEIV
                     PGDGGYVLNADIEIDLNPRLIDAVTRGVSLYFTTEVVIERPRWYWLNETVARRSLDYR
                     LYYHAITRSYRLSVGNLHQNFDELDAALRTMQRVRNWLVAETDVLQAGVSHEVSLRFR
                     LDTSQLPKPFQVTAIGSSDWNVETDWVRWTFLPGAPGFR"
     gene            complement(30285..31592)
                     /gene="rsmB"
                     /locus_tag="P5537_05715"
     CDS             complement(30285..31592)
                     /gene="rsmB"
                     /locus_tag="P5537_05715"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004315378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HRV77574.1"
                     /translation="MRSAPRRVPEQPIDSLGYALARAAGLVAGVIAGANLTDAFERLL
                     AEHPEWPEATRGAVRDLAWSTLRDYGRGDAILARLLHSPPPVEIRALLLVALQRLTQR
                     PEQAHTVVDQAVGAAAVAMPGLRNLVNGVLRNALRRQPEWQGWIEAAPDARHAFPAWW
                     VARVHRSYPQVWQEVLAAGNTRPPMALRVNSRRATLPAVEAELAEAGLEFRRLDNDAL
                     LLGRPLAVARLVGHAEGRLSVQDAGAQWAAHLLGAQDGERVLDACSAPGGKTAHILER
                     AAAELLALELDPVRAGRVERNLARLGLRAELKVADCRRLASWWDGRPFDRILADVPCS
                     ASGVVRRHPDIKWLRRDTDIANFAAQQAEILEVLWRTLAPGGTMLYVTCSVFDEENAG
                     QIARFCLRHADAERLPIRGNPDLQLLPCADHDGFYYALLRKRP"
     gene            complement(31701..32585)
                     /gene="speE"
                     /locus_tag="P5537_05720"
     CDS             complement(31701..32585)
                     /gene="speE"
                     /locus_tag="P5537_05720"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HRV77575.1"
                     /translation="MSEPLPDLPEGVLAELVSEDAGYFLRGARLLEGGHSEWQTYEVW
                     DTPRFGKLFRLDGCFMTSERDEFYYHENLIHVPGVAHPGLRRALIIGGGDGGSADELL
                     KYPGVERIVIAELDAKVVELSRRHLRAVHHGALDEPRVEVRICDGMKYVHEDGPAAGE
                     RYDLIVLDLTDPVGPAEALYAADFFAACKTLLAEGGALTLHIGTPVYQPERVRELVAR
                     LRRVFAKVRPYFLYIPLYGSLWGMACASDTLDPAVLDAGEVDRRLATRAIRELQHFNG
                     AVHCAQFALPNHLRVLLA"
     gene            complement(32589..32975)
                     /gene="speD"
                     /locus_tag="P5537_05725"
     CDS             complement(32589..32975)
                     /gene="speD"
                     /locus_tag="P5537_05725"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004014 - adenosylmethionine decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0008295 - spermidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HRV77576.1"
                     /translation="MNGLHLIGDIYRCRGAHDTLTRRSALEELCVGECRDAGLTPLGA
                     YFYQFENADGEAAGVTGTVVLAESHLAIHTWPETGDATLDVYVCNFSRDNSARARQVF
                     RRVIEVLAPAEIVAHEVVRGRLPVGV"
     gene            complement(33106..33876)
                     /locus_tag="P5537_05730"
     CDS             complement(33106..33876)
                     /locus_tag="P5537_05730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004315374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HRV77577.1"
                     /translation="MDTEFLFLALGLAALFAGFVDSIVGGGGLIQLPALFAAFPSTAP
                     ATLFGTNKLASIVGTTSAAIQYSRRVEIPWRVAGPGALAALVGSWYGAKAVAYLDPAI
                     LRPLILALLVLVAVYTFLRKDLGSVSKEPEHGGRSVAIALGVGGAIGFYDGFFGPGTG
                     SFLIFLFIRLLGMDFLRASVSAKILNVATNLAAIGFFAGNVELMWKLAAVMAACNLTG
                     SILGSRMALKHGTGFVRRMFLAVVTVLILRLAYDTFLR"
     gene            complement(34087..35433)
                     /gene="mnmE"
                     /locus_tag="P5537_05735"
     CDS             complement(34087..35433)
                     /gene="mnmE"
                     /locus_tag="P5537_05735"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HRV77578.1"
                     /translation="MESRPASPPDTIAAIATAPGRGGIGVVRVSGAGLGAFALALCGR
                     APRPRTAHFTRFLDEHERPIDEGVLLYFAAPASFTGEDVIELQGHGGPVVMQMLLERC
                     LQLGARLAEPGEFTRRAFLNGKLDLAQAEGVADLIEASTAAAARSAVRSLSGQFSEEV
                     HRITDALIDLRMLVEATLDFPEEEIDFLERARAMPRLEGIREALEGVLDRARQGALLR
                     SGLNVVLVGAPNVGKSSLLNQLAGEERAIVTDVAGTTRDALRETIQIEGIPLHIIDTA
                     GLRDTEDRVERIGIERTWREIARADVILHLVEAGVATEVDLDESLPQGVERIVVANKI
                     DLVGLPPGRVEAGGRVRLQVSARSGEGVELVRQELLRIAGWHAHGEDVILARERHLLA
                     LREALRHVEAAGTQLGALELFAEELRLAQEELGTITGEFSADDLLGVIFSRFCIGK"
     gene            complement(35405..>36780)
                     /gene="yidC"
                     /locus_tag="P5537_05740"
     CDS             complement(35405..>36780)
                     /gene="yidC"
                     /locus_tag="P5537_05740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HRV77579.1"
                     /translation="RLELKQHKASGEAGGNFVLLDDGTTRHQYAAQSGLIGEGLPTHK
                     TLFQLPAGELRLKDGENAVELRLQAPEHNGVQVTKVMRFARGSYLIDVAYEIRNGSGQ
                     AFAPHAYFQLTRDGNPAEQVEAFGVTTFTGPAFYTDANKFQKVQFADITEGDAKFPKT
                     AADGWVAMVQHYFVGAWLPKEGEQREYFARALGNNLFSAGVILPVASIAPGAEGTVST
                     RLYAGPQEQDKLEGIAPGLDLVVDYGWLTVIAAPLFWVLSWFHNLTGNWGWAIILVTV
                     AIKAIFFPLSAASYKSMAKMRVLGPRLQRMKEMYGNDKAKMQQEMMNLYRTEKINPLG
                     GCLPILVQIPVFIALYWVLLGSVEMRHAPWLGWIQDLSAKDPYFILPIIMGVSMLIQM
                     KLNPTPPDPIQAKVMMAMPIIFTFMFLWFPSGLVLYWVVNNCLSIAQQWQITRMIESG
                     KSAGKPA"
BASE COUNT         5576 a        12804 c        12923 g         5477 t
ORIGIN      
        1 gatccgtgcg cagatggtgg gcctgatggc cgggccggcg gccgagcaga tcttccgcgg
       61 cgaggcggtg cgcctgtgcc cagcgggcga gttcgatgaa gtgcggcaag cggaggatct
      121 gtcctggctg ctggctgcgc gtgacgcgtt cgccgacgcc gtggcgctga cggcgcacac
      181 cttgagccag cccgaggtat gggccgcggt cgaaagcgtg gcgcacgaac tcgagcgtgc
      241 gggcacgctc acccgcggtc tgcgcgggct actgcccgcc gccctgcccg actggccgcc
      301 aggcggctcc gcagcgtagc ctggcggcac aacgcctccc cgaccgcctc gccccgcaag
      361 actcccctca ctcggccgcc ctctcccgag ccggggaagg catccgccag ggtgaggaat
      421 cttcttcccg gggccggcgc acgcggcgaa gagccggcgg gcgtccgggg cgaagcgagt
      481 gtcgtccgcg atcgtcaccg agctggccgt cctcgcgagt ggagtgctac gccgccgtgc
      541 agggcggccg cttgctcagg gctgggggtc ggcccgccgc ccttcgtcca tgcgccggat
      601 cgcctcctgg ccctggtggg cgaggccggc gaggcggtcg atctgggcgt cgagcttggg
      661 cagggcctcg cggcggtagc gcgagaggtc gtcgatggcg ccgagcacgt cgccgaaggc
      721 ctgttcgagc tggcccatgt cgagcatgga cgaggacgcg cgggtctgga tgtccacgcc
      781 ctgggtgcgc agggcctggg cggtgccagc gatgagcgcc gaggtggtct cgttgagcgc
      841 ggcgacgcgg tcgagcacca ggcgctggtt ggccaggccg agcgcgacgg tgacggcgac
      901 gttgagcgcc gacacggtga cgttgatcgc gcggtccacg ccgcgcacca gctcgcggtt
      961 gttgcggatg acgacctcga gcgcgagcac gccctgctgg ctcaccgcca cctgctgctg
     1021 caggtcgacg atgcgctggc gcagcgggaa gaggagctct tcctcgacga aggcacggcg
     1081 cggcgccggc agcccggcgg aggcggcctc gcgcgcgagg cggcggtcga tcatgcggcc
     1141 gagttcgacc tggcgctcga gctgggcgag gatggcgcgc agcgactgct ggtcgtcggc
     1201 cagggtgagg ttgtcgcggc gcagcatgtc ggcgccgctc tgcaggtcgc ggatgatggc
     1261 gtcgagcgcg tcctgcgcct tctcgtactt ctggaagtag cgctgcatcg gcttgccgac
     1321 gccggggatg aaggacagcg cgcgcgacag gccctcgccg ctcagcttct ggcgcgcggg
     1381 gtcgaggtcc tgcatcttgt cgcgcagcgc gagcagggcc tgcgccaccg ggccgccctc
     1441 gtcgccctgg tgggcgagct tgcggatcgg cgcctgcagc atctcgctgc gccacgcggc
     1501 ctggcgctgc agctcgatgc ccatggtgtc gaccgcctca cgctggcgct gcagcgcctc
     1561 ctcgccggcg gcgagcgcgt cgcgcacgaa ggcgtcggcg agcggggcga gctcggcgtc
     1621 ctcggccggc tcggcgtcct gcggcggcag ggtctcgcgc gcgatgtcct cgatcggcgg
     1681 cagcgacagg cccgagcgcg ggcgcccgcc tccgcccagg tcgcccccgg gggcgcgggg
     1741 aaggatacgg agaagggatc gcagcggcag gctcatcggg gctttcctcg gttcattgct
     1801 ggcggccgta gaggccggcg cgctcggcga agcggcgcag ctcctgcagg gcctgttcgg
     1861 tggcgcccgc gggctggccg cggccggtgt cgatgcgcgc caccgcgacc gcgacgtggt
     1921 cgagcgcggt cagcgccgcc tcgttgccgg cggcgatctc gccgaggcgg cgctcggtct
     1981 cgtcggcaag ggcgaggcgg cgctgcagcg cctcgcgctc ggtgccgccg aggcgggcgg
     2041 cctcgcgctc caggcgctcg cgcacgaagt cggcgtcgag accgacgctg ccctgcacca
     2101 gcgcgaccat cgcgcccagc ccggcagcgg cgccgctgcc gacctcgccg accaggccgc
     2161 gggcgcgctc gtaggtgacc tcgcggcggt cgaacttctc gtcgagcacg tcgagcgcgc
     2221 gatggtagcg ggtgaacagg cggtcggcct gcacggcgag gtcgggccgg cgcaggccga
     2281 cgagctcgcg cttgacctcc cacagctgca tcaccaccgc gtcggcgtcg gcggggacga
     2341 aatcggggtc cagggtcagc aggtcacgct cgcggcgtcc gcgcgcgagc tcggtgcgtg
     2401 cgcgctcgcg cgcggcggcg cgctccttgc cggcgcgcgc ctcacgccag cgccgccagc
     2461 gccgctccag gaagagcgcg gccggggccg cggcgaggcc ggcgagccag ccgccgaggc
     2521 tggcgccgaa gccgccccac agcgaggtca gcagcagcag ggtcgcgacc gagggcatgg
     2581 ccaccgcgta gcgcaggatg acctgccagc gcgaggcgag ctcctccggc accaccaggc
     2641 gcgggtcgta catcccggcc atgaaccagg gcacgaagga gaccagcagg ccgaaggcga
     2701 tcccttggag aaattcgaac atcgaggcct caagttgcgt tgcgggacgg gagcgggcgg
     2761 gccgtgaacc gctcaggctc gaacgctgca ttcgcgcctg ccggcgctcc tacacaaacc
     2821 gccgcggctt cggcccatgt aggagcggcg gcagccgcga atgtaggagc tgcggcagcc
     2881 acgaatgtaa gagccccgac agccgcgaat gtaggagcgg cggcagccgc gaatgggcgg
     2941 tcggtcgcag gatgggtgtg caggtttcga tcgctgcatg cgcgggcaag cccgctccca
     3001 ccgggaccgt atgctccgca tgcaccgcag gcccgccgct cccattcccg tccgcagtcc
     3061 catccccgcg taccgcttac cttgcggcga gcgccgggtt gagcgagtag gtgccggtga
     3121 gcttcacttc ggcgagcacg tggccggcga tcgccgcgcg cgcgtccgcc ccggtgaagc
     3181 ggccctcgac cgcgcagcgc gcgacgtcga gcgcgtacaa cgtgaacacg tagtggtgca
     3241 cgatctcgtc gttccacggc gggcaggggc cgtcgtagcc gtgatagtcg cccttcatcg
     3301 attcgtcgct ggcgaaccag gcggtgtaat cgttcacgcc gtggcgggcg ccgagcgcgg
     3361 cctccgggcc gggcttgccg cccggcgtga cctcggcgga gaaatgcccg gcttcgatcg
     3421 cacgcaactc ggcgggcagg tcgaccacca cccaatggaa gaaatccacc cgcggcaggc
     3481 tggcgggcac cgtgcggcct tcctggttga cgtcgtcgcc cttgctcggc acgtcgggat
     3541 cgtgacagat cagcacgaag gacttcgtgc ccgcgggcac ctcggaccac gacagctgcg
     3601 ggttgcggtt gccgcccagg cagacgtggc cttctgcggc cggaatgcag aaggcgaatt
     3661 cgcccgggat gcgggcgccg tcggtgaagc tctggctggt gagtttcaag gcatcctcct
     3721 tgcggtgtga tgtgggtatg cgagcacgcc ctttcaaggc gcgtcgcaca ggcagtgcag
     3781 gtagtggtgg cggggatcgt tccagcgcag cagctcgcgg gcggcgcgct ccacgtcggc
     3841 ggctgcgacg gcgagcggcg cggccggcgc ggcgcggccc gccaggtcga tgccgaggtc
     3901 gtcgccgacg cgcagcagcc ggcgcagcag gcgctgctcg agcgactcgc ccgccgccgg
     3961 ccacaccacg tcgtgcgtgg cgaggccggc gcgcgcggct gctgcggcga tggcgtcttc
     4021 gaggccgccg agcttgtcga ccaggcccag gctgctcgct gccgccccgg tccacacgcg
     4081 gccgcgggcg accgcatcga cctcttcgac cgtcatcttg cgcgcctgcg cgacgacctc
     4141 gaggaagcgc cggtagccgt gctcgatgcc gagctgcatg gcctcggccg cggcggggtc
     4201 gagcgggcga cgcggatcga gcgcgccggc gagcggcgcg gtggcgacgc catcgacgcc
     4261 gatgccgagc cggcgcagcg gttcggagaa ctcggggaag aggccgaaga tgccgatcga
     4321 gccggtcacc gaggacggcg ctgcccagat ctcgtcggcg ccggtggcga tccagtagcc
     4381 gcccgaggcc gccaccgagc tcatcgacgc gatcaccggc ttgccggcct cgcgggtgag
     4441 ctgcagctcg cgccggatca gctcggacgc ccaggcgctg ccgcccgggc tgtcgatgcg
     4501 cagcaccagc gccttgatgt cctcgtcctc gcgcgcctcg cggatcagcc gggcgaaggt
     4561 gtcgccggcg accacgccgg ccggctcggc gccatcgacg atggtgccct gggcgacgat
     4621 caccgccacg ttgccggcgg catcctgggc gtcgtccgcc gcgagcgcga gataggcgtc
     4681 gacctcgatg gcgcgcacgt ccttgccctc gtggtcggtg cccacggcct cgatcaggcg
     4741 ggcgcgccac tcgtcgcggg tgctgaagcg gtccaccagg cccgcggcga gcgccgcctt
     4801 ggcggcatcg cccccggcgg tggcgagcgc gccgcggatg tcgttcacat gcgcgtcgac
     4861 cgccgcgggg gcgagcttgc ggctggcggc gatgtcgtcg cgcatgaagc gccacagacc
     4921 gtcgagcagg tcgcgggtgg cctcgcggtc ctcgtccgac atgtcgctgc gggtgaaggg
     4981 ctcggagaag gacttgtatt cgccgacgcg gaacacatgc accttgacgc cgagcttgtc
     5041 gagcgcgtcc ttgaagtagg agccgtagcg cgccaggccg cgcagcagca cgaagccgtc
     5101 gggcgacagg tggagctcgt cggccaccga ggcgaggtag tactgcgact gggtgaagcg
     5161 ctcgccgcgc gccagcaccg gcttgcccga ggtcttgaag tcggcgatcg cggcgcgcag
     5221 ctcggcgagc ttggagaagc cgccgccgac gagttcgtcg gtctcgatca ccagcgcggc
     5281 gatgcgcgcg tcgtcgcgcg ccttgcgcac cgcgtccacc aggtctgcca ggcgcagctg
     5341 gccggccggc gctcctccgg cgcgcaacag cgccagcggc ggctcgagct cggcctgctc
     5401 gacgatggtg cccaccggcc gcagcaccag cgcggatccc gccggcacct cgggctcggg
     5461 gtggaagaag aaggacacca gcacgccgag gccgaagatc agcaaggcgt agaagacgcc
     5521 gcgcacgacc aggtcgagcg cgcgcacgaa catgcgcagc acgttcagta ggaagcggaa
     5581 caggccccgg atcatgcggc ggtgtcctcg ttacggatgg ttcagcccgc gcggcggcgg
     5641 aacacgaggt cccatacccc gtgtcccagc ttcagaccac ggttttcgaa tttcgtcagc
     5701 ggccggtagt cgggacgcgg tgcaaaaccg tcggcggtgt tctgcagcag cggctcggcg
     5761 gagatgatct cgagcatcca gtgcgcgtag tcctcccagt cggtggcgca gtggaagtag
     5821 ccgccggggg cgagcttctg cgcgatcagg gcgacgaagt cgggctgcac gatgcggcgc
     5881 ttgaagtggc gcttcttgcg ccaggggtcg gggaagaaca gatgcacgcc agcgagcgcg
     5941 ccgtcggcga tcatgtcgcg catcacctcg acggcatcgt gctgcatgat gcgcaggttg
     6001 gtgagattgc cctcggcgat cagcttgcac agcgcgccga cgccgggggt gtgcacctcg
     6061 atgccgagga agtcgtggtc gggcatcgcc gcggcgatct tcgccgtggt ctcgcccatg
     6121 ccgaagccga tctcgaggat cttcggcgcc ttgcgcccga aggccgcgtc cagatcgagc
     6181 ggcgcggcgc ggtagtcgat gccgaccttg ggcagcatgt cgtcgaggta gcgctgctgg
     6241 gcctcggaca tgcgcccctg gcgcagcacg aagctgcgga tgctgcggct ggagaagcgg
     6301 tgctcggggc tgtcgcggcc gatgatctcg acgccggcca cgacttcgtc tcgtacttcg
     6361 ctcatgaacc gatcagcccc tgggtcggcg agctcgggtc ggccgagtag aacttgcgcg
     6421 gcatgcgccc ggcgaggaag gcctcgcgcc cggcctcgac cgccttcttc atcgcgctcg
     6481 ccatcagcac cggccggccg gcggcggcga tcgcggtgtt catcagcacg ccgtcgcagc
     6541 ccagttccat cgcgatcgcg gcatccgagg ccgtgcccac gccggcatcg accagcaccg
     6601 gcaccttggc gttgtcgatg atcaggcgca ggttccacgg gttgaggatg cccatgccgg
     6661 agccgatcag cgaggccagc ggcatgatcg cgcagcagcc gatgtcctcg agcatcttcg
     6721 cctggatggg atcgtcggcg cagtagacca tgacgtcgaa gccgtccttg accagggtct
     6781 cggcagcctt gagcgtctcg ggcatgttgg ggaaaaggct cttggggtcg ccgagcacct
     6841 cgagcttgac cagcgcgtgg ccgtcgagca gctcgcgcgc caggcgcagc gtgcgtaccg
     6901 cgtcgtcggc ggtgtagcag ccggcggtgt tgggcaggat ggtgaatttc tccggcggca
     6961 gcacgtcgag caggttgggc tcgcccgggt tctggccgat gttggtgcgg cggatggcca
     7021 cggtgacgat cgcggcgccg ctggcgtcga tggcttcgcg cgtctcggcg aagtccttgt
     7081 acttgccggt gccgacgagc agtcgggagt gataggcctt gccggcgatg accagggggt
     7141 cgttcatgtt gggagcctgt gaaggttgat ctgaaaggga ggcgtcggct gcgccgacaa
     7201 gcgcctgtag gagcggcggc agccgcgaaa ggggcttcgg catccgcggg gcattcggcg
     7261 gccgccccgt cgagtcggcg taagcgcggt cgcggtcggt gggcaccctg ttcgcggctg
     7321 ccgccgctcc tacaggggtg ccgtggggcc gtaccgtcag ccgccaccca ccgcgacgac
     7381 gatttcgagc ttgtcgccat cggcgagttt cacctcggcg tggcgggcct tgggcacgat
     7441 ctcgccgttg cgctcgaccg caaggcgctt gccggcgagg ccgcgcgcct cgagcagggc
     7501 aagcaccgag agttcgggct gcagcgattc gggctggccg tttaggatga cctggatcat
     7561 ggcgttcggg gctgtgcagg agcggaaaat cttatcatgc cggccgtttg acttttccct
     7621 tcccgggcgc taacttccaa ccacctagcg ccgatttgat caacagcttg cgggcgctca
     7681 acaaatacgg ctaaagcgag ggcacccagt ccgcgtttgc agccggctgg gttttttgtt
     7741 tgcagatgac gaaaatgatc gcaccccaat cggtcggcgt ggtcgtgccg cagcgggccg
     7801 agttcaccac gccgctcgcg ctgcgcagcg gcggcacgct ggacaactac cacctcatct
     7861 acgagaccta cggcacgctc aacgccgagc gcagcaacgc ggtgctggtg tgccacgcgc
     7921 tgtcgggctc gcaccacgtc gccggcacct acgccgacgc gccgcacaac gtcggctggt
     7981 gggacaacct gatcggtccg ggcaagccgc tcgatacgcg caagttcttc gtgatcgggg
     8041 tgaacaacct cggcggctgc tacggctcat ccggccccaa ccagaccaac cccgccaccg
     8101 gcaggctgtg gggcgcggac ttccccttcg tcaccgtgga agactgggtc gaatcgcagg
     8161 cgcgcctggc cgaccagctc ggcatccggc gcttcgccgc gatcgtcggt ggctcgctcg
     8221 gcggcatgca ggcgatgtcg tgggcgctgc agtaccccga ccgcgtcggc cacgtcgcgg
     8281 tgatcgccgc cgcgcccaag ctcaccgcgc agaacatcgc cttcaacgag gtcgcgcgcc
     8341 aggccatcct gaccgacccc gagttccacg gcggccacta ctacgcgtac ggcgtggtgc
     8401 cggcgcgcgg actcaagctc gcgcgcatgg tcggacacat cacctacctg tccgacgacg
     8461 cgatggcgga gaaattcggc cgcagcctgc gtcacggccg caacacctac agttacgacg
     8521 tcgagttcga gatcgagtcc tacctgcgct accagggcga caagttcgcc ggcttcttcg
     8581 acgccaacac ctacctgctg acgaccaagg cgctcgacta cttcgacccc gccttcgagt
     8641 acggcggcca cctgcccgcc gcgctcgccc gcgccaccgc cgacttcctg gtggtgtcct
     8701 tcaccaccga ctggcgcttc tcgcccgagc gctcgcgcga gatcgtctac gcgctgctgc
     8761 acaaccgccg caacgtcagc tacgccgaga tcgactgccc ggccggccac gactccttcc
     8821 tgctcgacga gccgcgctac cacaagctgc tgtcggcctg gttcgaccgc atcgaggtgt
     8881 gaattgacaa cccccacgct ctctgcgttc gctgcccccg agggggcgtc agtacgcttg
     8941 agacggctct gcgcatactg atatgactgc ctaccgctac gactatgaag tgatcaccca
     9001 gtggatcgag cccggcgaga aggtgctcga cctcggctgc ggcgacggcg aactgctccg
     9061 ccacctgatg gatgtgcgcc aggtgcaggg ctacggcgtc gagaacgacc cggacaagct
     9121 gctcggcagc gtcaacaacg gcgtcaacgt gatccagatg gacctggaga agggcttggt
     9181 ggggctggag gacggcttct tcgaccacgt catcatgagc ctgtcgctgc aggccatgca
     9241 caacacccag ggcatcctcg ccgagatgct gcgcgtgggc cgcgaggccg tggtgagctt
     9301 ccccaacttc ggctactggc gccaccgcca gagcatcctc aacggccgca tgccggtgtc
     9361 ggagagcctg ccgcaccagt ggttcaacac gcccaacgtg cgcttcttca ccatcgccga
     9421 cttcgacgcg ctgtgcgagc tgaacggcat cgcggtgcgc gagcgcctgg ccttcgacga
     9481 gggcaagctg gtactcgacg agccgaactt cctcgccagc gtggcggtgt acaggctggg
     9541 acgcaacggc tgaggcgcgc tggcgccggc ctcctatact gaaccgtgac cgcgccgcgg
     9601 tcccgggcac aggagacgcg cagcgatgca ggagaacagc gaggccgtcc tcgtcgccac
     9661 cggcgcgctg ccggcgctga tcctgatcgc cgctgcgctg accctgccgg tgtgcctggc
     9721 gctgctggcg ctgtatcggc gggcggtgct gcgctcgatg gcgctcgcca gtccggcggc
     9781 ggggagcgcc gcctcgcacc cgcaggaaac cccctccaca cccgcgacac caccgaccgc
     9841 catgctgcgc ctggagcctc gcgagagtgg cgcggcgggc gcccgccccg cgctggcgag
     9901 gatgcggcga tcgctgcgcg cggccggcct cgtccacctg ctcgccggtc tcgcctatgc
     9961 cctcgtgctc accaccgcgt ggatgcagtt cacctgggaa gacggcggct tcgtgcccac
    10021 gcgctttctc ctcgtgttcg cctgccacgc ctggccggcc gtgctcgccg tcgggctggt
    10081 gacggcaggg acgaggcggc agcgcctgac gctggggctg gcctatctgc tgatcgttct
    10141 cgccctcgcg gcctgggcgc tggcgcgcaa cccggcgctg cccgcgctcg agctcgcgcg
    10201 cctgtgggcg agcatcaacc tgccgccgac cgtactgctg ctcgccttcc tgcaccggcg
    10261 catccgcgcg gtggggccgc tggtgctcgc tttcatgctg gtcgcggtga tcggcgccga
    10321 ggcggcggtc cggctggcgg ggcagagcga ggccacgatg cgcctcgcgg tcggcgccgg
    10381 cggcgcgctc ggcctcgacg gcacgcagac cttctgggca ctcctgctcg cgggggccgc
    10441 cgtcgctgcg ctgctcgggc ggctggtgct gaagtggctg ggcaggcggc acgtcgcgcg
    10501 gcgcagcagc gaccagatcc tgaccctgga ggcgatgtgg ctgctgttcg cggtggtgca
    10561 gtcggtgggc ttcgccttcg aggggctcgc ctggctcgcg gccggcccgc tcgccttcct
    10621 cgcctggaag ctgacgaccg tggccgggtt ccggctcgcc gggctcgggc gcgcgcaagg
    10681 accggcgccg ggactgctgc tgctgcgcgt gttcgcgctc ggcgcgcgca gcgagcgcct
    10741 cttcgacgcc ttcggcaagc gctggctgcg catcggccac atcgacatga tcgccggccc
    10801 cgacctcgcc accacggcgg tcgagcccca cgagttcctc gacttcgtcg gcggacggct
    10861 gtcgcgcgcc ttcgtgcgcg acgaggccga cctcgcccgg cgccatcccg cgcgcgcgct
    10921 ggggccggat ccggacggcc gccaccgcgt caacgagttc ttctgccacg acgacacctg
    10981 gcgcccgacc atgctgtgcc tggcgcgcgc cgcggatgcg gtgctgatgg acctgcgcgg
    11041 cttctcgccg cagaacgagg gctgccgcta tgagctgcag cagctgctcg accacgtcgc
    11101 cctggagcgc gtggtggtgc tggtggggcg cgacaccgac aggggctttc tggagaggac
    11161 gctggccgcg ctatggcagt cgagccgagc aggctccccc aaccgcgaca acccgcaccc
    11221 gttgctgcgc atggtggagg agcgcgggga cgataccgcc gcgcgcctgg tcgaagcctt
    11281 gctggaagca ccgccgcgcg cagcggcggc ctgagcggaa agagggatca gccgaccacg
    11341 aaggacgaga cgtccacccg caccgcagga cggtcgagcg cgaccgcggt atggagcgca
    11401 tacttgcgcg cccattcgcc agcctgctcg aagcggcctt cgccgccgta cttggcgacg
    11461 ttgagcacca tgtcgaggac gagcaccttg cccatcgggt tggacggggt gcactcgaga
    11521 tcctcgaatt ccctggcgag ccagctgcgg gcctgctcct tggtggtcga ggcgacatcg
    11581 gcatcgcgca gcgggaactc gtactcgcgc tcgcctccga agaccacggt cacggtgtgg
    11641 gacatgaaaa acgacctcca cgaatcgggg aatttggctt tcccggcatt gttgagtcag
    11701 aacgtgtcag acgcaagcaa agtatcgaat tgtgtaaacc ggggggccgc ggatgatctg
    11761 cgataatgcg cggccctgca atgcccgccc gccatctctt gtccgttcct ccccgacccg
    11821 ccctcgcccg tgcctggcgc ctgtccgcca tcctggtgct cggcttcgcc tccggcctgc
    11881 cgctggcgct gaccggccag gccatgcagg cgtggctgac ggtcgatggc gtcgacctcg
    11941 ccaccatcgg cttcttcggc ctggtcggcg tgccctacac cttcaagttc ctgtgggcgc
    12001 cgctgatgga ccgcttcgag ccgccctggc tgggccgccg gcgcggctgg ctggcgctca
    12061 cccagctcgc gctggcggtg ctgctgtggt ggatggcgag cctgtcgccg acggccacgc
    12121 cgggcctgtt cgccgccgcc gcggtggcga tcgccttcct gtcggcctcg caggacgtgg
    12181 tggtcgacgc ctaccgcacc gacctgctgc cggaggccga gcgcgggctg ggcgcctcgg
    12241 tgcacgtctt cgcctaccgc ctggcgatga tcctgtccgg cggcatcgcg ctgatctggg
    12301 ccgggcagtg ggcgtcgtgg ccgcgggtgt acgagaccat ggcgctgatc atggcggcct
    12361 gcgccgtggt gtcgctgctg gcgctgccgc gcgtgtcggc ggcgctgaag ccgctagcct
    12421 ccgaccccag gcgcgagctg ctcggcttcg ccgcgatgct cgccggggtc gccgccggct
    12481 actggatcgc ccgccaggcg ctgatcctga tcggcctcga ccccaacgac gccaaccgct
    12541 ggatccagct cctgttcgtg atggcggaga tcgcgctggc gctgccgctg gcgggctggg
    12601 cggcgcgtcg cgccggcttc gagacgctca accgctcgct gtcgagctac ttcgcgcagc
    12661 agggcgcggc ggccttcctg gcgctgatca tcctctacaa gctcggcgac gccttcgccg
    12721 gcagcctgac cacgcccttc ctgatcaagg gcatggggtt ttcgcaggaa gaagtcggta
    12781 tcgccaacaa ggtgatcggc atctggctga ccatcctcgg cgccttcatc ggcgggctga
    12841 tcatgacgcg gctggccttg taccgctcgc tgctgctgtt cggcgtgctg cagctggtgt
    12901 cgaacttcgg tttctacctg ctcgccgagc tcggcaaggg tgcctggggc gccgtgatgg
    12961 tgccggcctt cgactggggc ttcgtcgcgc tggatgcgcc tgccgcgctc gacgggctgc
    13021 tgctgacggt gatcgccggc gagaacatca gcggcggcat gggcacggtg gccttcgtcg
    13081 cgctgctgat ggggctgtgc aaccagcgct tcaccgccac ccactacgcc atgctgtcgg
    13141 ccttcgccgc ggtgggccgg atctacgtca gcccgctgtc gggcgtgctg tcgcagtcga
    13201 tcggctggcc ggccttcttc atcttctcga tcgtcgtcgc cgttcccggg gtggtgatgg
    13261 tgtggtggct gcgcgacgcc ctcgcccgcc tcggccgccc gcagaccgac ggcgcggtgg
    13321 acgactgatg gcgcacacag gcacgagcgc acgccgcgag ttcctcgccg gctgccgcga
    13381 cgaggcgccg ctgctgctcg gcgtggcgcc cttcggcatg atctacggca tcgccgcgct
    13441 cgccgcgggc gttcccgcgt ggctggccca gctcgcctcg gccatcgtct tcgccggcgc
    13501 cgcccagctc gtcatcgtgc agatgctggc cgcgggcgcg ggcttcgttc ccatcgcgct
    13561 cacctccggc ctgctcaacc tgcgccacgt gctctacagc gcgtcgatgg ccgattacgt
    13621 gcaccacctg ccgcggcgct ggcgcctgct gctggcctac gtgctcaccg acgaggccta
    13681 cgcggtggcg gtgctgcgct accagcagcg ccatgcgggc gaggcggacc aggctgaaca
    13741 ggcggactcc ggcacgcagg ccggggggat ggaccaggtc gccgacctgc gccactggta
    13801 cttcctcggc gccggcttca cgctgtgggc gggctggcag ctgtccaccg ctgccgggct
    13861 gctgttcggc accaccatcc cgcccgagtg ggagctcgac ttcgcggtgc cgctcacctt
    13921 catcgccctg ctcaccctgc tgctgcgcga gcgcgccggc caggccgcgg cactggtcgc
    13981 cgcgctcggc gcgctcgcct tcgccgccct gccctacaag ctcggcctgg tggcggcgat
    14041 cgtgctcggg ctcaccgccg gggcatggac cgtacgccgg ctggagcatg cccgatgagc
    14101 acgacgaccc tgctcctgct gctggcgctg gtcggcgggc tgacctacct gtaccgctac
    14161 gcgatgatcg gcctcttcgc cagccgcagc ctgcccgcct ggctgcatgc cctgtgccgc
    14221 cacatcgcgc cggcgagctt cgccgcgctg accgcgagcg cgctcttcgt cgccggcggc
    14281 gaggtcgtgt tcgccttcga caccccacgc ccgtgggcgg cgctggtcgc ggtgctggtg
    14341 gcctggcgca cgcgcaacgt gctcgccacc atcggcgccg gcatggccgc cctctacctg
    14401 ctcaagctgc tcttcccgac atgaccgccc gcatcctgat cgacgccgcc cgcgaactgt
    14461 ccgccgcggt ggacgcactg cccttcgcgc cccccgtcac ccatgtctac aacccgctcg
    14521 actacgcctg ggaggtgcat cgaagctacc tcgagcgcta tggcgacggc cgccgccgcg
    14581 tggtcttcgt cggcatgaac ccgggcccct tcggcatggc gcagatcggc gtgcccttcg
    14641 gcgagatcgc cagcgcgcgc gactggctgg ggctggaggg tccggtcggg cagccgcgcg
    14701 tcgtcaaccc gaagcggccg gtggaaggtt ttgcctgctc gcgctccgag gtgagcggcc
    14761 agcgcctgtg gggcctgttc cgcgcccgct acggtgcgcc cgaggccttc ttcgccgaac
    14821 acttcgtcgc caactactgc ccgctggtgt tcttcgaggg cggccgcaac ctcacccccg
    14881 acaagctgcc gatggccgag cagcgcccgc tgctggccgc ctgcgacgcg cacttgcgca
    14941 ccgtggtcgg ggcgctgcag cccgaatggg tgatcggcat cggcaactgg gcggagaagc
    15001 gttccagcga ggcactcgcc ggactgcccg ggctgaagtt cggccgcgtg ctgcacccca
    15061 gccccgccag ccccgccgcc aaccgcggct gggccgaggc ggcgacgaag cagctgacgg
    15121 aactggggat ctggcctagc tagccagcgc tgtcgccgat cggtcgatgg ccgtggttcg
    15181 cggcttgcgc cgctcccgct ttatgtagga gcagcagcag ccgcgaactt ttctacggca
    15241 gccgcaggct cagtgcccga acacgtccga atccagcatc tccggatccg ggcggtcgag
    15301 cgcgctgatc gcggcgagtt cctcggcgga gagctcgaaa ccgaacacgt cgaggttctc
    15361 ggcgaggcgc tgcgggttgg acgacttcgg gatcggcacg tagccgagct gggtgtgcca
    15421 gcgcaggatc acctgtgccg gcgtgcggcc atggcgccgc gccacgtcga ggatcgccgg
    15481 gtcaccgagc atcgcgttgg cgcgcccgag cgggctccac gactcggtga cgatgccgcg
    15541 cgccttgtgc acatcgatat ggtcgctgcg cgcatgccag gggtcgaggt ggatctggtt
    15601 cacctgcggg cacagaccgc ggtcgaacag ctgctgcaga tgggcgggct tgaagttcga
    15661 ggtgccgatc gcacgcacga ggccggcctc ctgcagcttc accaggccct cgaaggcctc
    15721 cacgtagcgg ccctggtcgg ggttgggcca atgcaccagg aaaaggtcga tgtagtccag
    15781 gccgagacgc tccaggctgg cctcgcaggc ctggcgcgcg ccctcgacgc tgtgccattt
    15841 gcggttgaac ttggtggtga cgaagagctc gccgcgcgcg acgccggagc gacggatgcc
    15901 ttcgccgacg ccgcgctcgt tctcgtagtt ctccgcggtg tcgatcaggc gatagcccat
    15961 gtcgagcgcg agcgcgaccg tctcggcggc ctcggcatcg ttcatcggcc aggtaccgag
    16021 gccgagccgc ggcatctcga caccgttgga caaggtgagc aggggagcag gcgtgatctt
    16081 catggaaatc tcgagaaagg gggttggggg ctacaggatt ccacattccg gagtcttgtg
    16141 taagcactct gggaggtctc ttcggcatcg atccacagga catcgcgccg cctcgggggg
    16201 agggaagccc ggccgtggca ccgacacggg ccatccggcg gtaacctccg ccacacgcga
    16261 tcctccctcc cgagatcatt tccaggggcg gttccacgtg aaaccacccc acgacacgcg
    16321 tccccgctca gcgccgcagt tcatccgtca ggcgcttcag gtcgagcgtg cgggcgcgct
    16381 gcgcgatctc gggcgcgtag cgctcctgca tcgccttggc ctgctcgaac aggccggcaa
    16441 aggcctggcg cagcgcatcg gtgtcaagct tgcggccgcc cccgtagtat tgcaccgcga
    16501 ccttgccgat cgcccaggtg gtggcgaagg agaaggcaga gccggtcgcc tggctgccga
    16561 ccgcccgccc cgccccgccc agcaccttgc cgagcaggcc gccgatcagc cggcggccga
    16621 actgctcgac gtactggccg gtcatgccca cgcccgctgc ggcgaggaag tccttgatgt
    16681 ggccgcggtc gagctcgtag ccgtgcgcct ggccgatgcg atacaccagg cgtagctgca
    16741 agggaatgat cgccatcgag gccatcgact gcggcaacag ctcgagcgcg ccgttgagga
    16801 tcgacgcatt caggatggtc cggtcgagtt cggccgtatc cggcgcagcc gcggcagtgg
    16861 acggcgcagc cgccggctcg tcctcgccca ggcccggcag ccccgcgagc ggccgttcgg
    16921 ccggcgcctg gccgatggcc tccgcctcgt gcacgaagga ctccgcagcc ggccgcgaga
    16981 gcgccagcaa gccggtcagg cgttcgagga agcccttctc gcggtcatcc agcccgccat
    17041 cggcctcgca cacgccgacc gccagctcga aggcgagctg gcgcaggttc gcctcgtcca
    17101 gtccggccac cgccgcctcc agctcgagcc ggccgagcag cacgtcctga tagagggcga
    17161 tgaaatcgat ctccgcctcg cggccgagcg attcggcgac cttgcgcacc tggtcgcgct
    17221 cctccgcacc ctggtggccg tcggcgaagg ccgcgtgcag gcagatggcg acgagggaac
    17281 gggcttgctg ggggttcaag ttcattgggc gactccgcag aggaaagctt gcagtttgag
    17341 gatggacggt ggagcttcaa gcgcggctga cacgctttta cgattcgacc ggcgcagccg
    17401 gcggacgatc cccggtagcg cgtgcccgag gtgtcggagg ctggccgcca ccggccggcg
    17461 cggacataat tacgcattac cgcatcccag gtccgcacac accatgtccc agtccatcga
    17521 acacctcttc gccaacaaca agaactggtc cgagcgcatg cactcggagg accccgagtt
    17581 cttcacccgc ctggtcaacc agcagtcgcc ggaatacctc tggatcggct gctcggacag
    17641 ccgggtcccg gcgaaccagg tgatcgggct tgcgccgggc gaggtcttcg tgcatcgcaa
    17701 catcgccaac gtggtcgtgc ataccgacct caacgcgctc tccgtcatcc actacgcggt
    17761 cgagatcctg cgcgtgaagc acatcctcat cgtcggccac tacggctgcg gcggcgtgaa
    17821 ggcggcgatg aacgacaaca agaccggcct caccgacaac tggctgcgcc acatccagga
    17881 cgtgcgcgac cgccacatcg accgcctgga gcgcttcacc gatccgtccg agcgcgccga
    17941 ccgcctgtgc gagctcaacg ccatgcacca ggtggtgaac gtttgccaga cctcggtgct
    18001 gcgcgaggcc tggcagcgcg gccagggcgt caccgtgcac ggctggtgct acagcctgca
    18061 ggacggcctg gtgcgcgacc tcggcgtcag ctcgcgcacc cgcgaggagg cggtggagcg
    18121 ctaccgcgac gcggtcgagc gcatcggctg aagccggtcg tcacaccatg gggacgcgca
    18181 tcggcatcga cctcggcggc accaagatcg agctggtggt gctggatgcc ggcggccacg
    18241 agcgctggcg ccgccgggtg ccgaccccgc agggcgacta cgccggcacc ctgcgcgcga
    18301 tcgccgcgct ggtggaagaa gccgagcatg tcaccggcgc gggcgcccgc gtcggcatcg
    18361 gcacgcccgg ctcgccctcg ccccgcgacg gccgcatccg caacgccaac tccacctgcc
    18421 tgaacggcca gccactgcag cacgacctcg aagccctgct gcgccggccg ctccgcctcg
    18481 ccaacgacgc caactgcctg gccatgtccg aggccgcgga cggtgccggc gcgggcgcgg
    18541 gcaccgtgtt cgcggccatc ctcggcaccg gggtgggcgg cggcatcgtc gtcgacggca
    18601 ggctgctcgt cggcgccaac gcggtcgcag gcgaatgggg ccacaacccg ctgccgctgc
    18661 ccgactccgg cgacctcccc ctgcccgtct gctattgcgg acgcgccggc tgcatcgaga
    18721 cctacctctc cggcccgggc ctggccgccg atcacctgcg ccacggcggc gagcctgtcg
    18781 acgccgcgag catcgcctgc cgcgccgacg ccggcgagcg cgccagccag gccagcctcg
    18841 aacgctacga ggcgcggctc gcgcgcgcgc tcgcgagcgt gatcaacctg ctcgaccccg
    18901 aggtgatcgt gctcggtggc ggcctgtcgc aggtcgcgcg cctgtacgag aatgtgcccc
    18961 ggctatggcc tgcgcacgtg ttctccgaca ccgtctccac ccgcctgctg ccggcacggc
    19021 acggcgacgc ctcgggcgtg cgcggggccg cctggctgtg gccggcggag tgagcgtggc
    19081 agcagggaat gcgctcgagc gcgctcgagc gcatgctcgc ggctgccgcc gctcctgcat
    19141 acatctccgc gcgaaaacgc cgcggtctcc tgtaggagcg ccggcaggcg cgaagggagt
    19201 gtcggccctc gtctcatccg ctctgatcgc tgtgtcgccg ctcctacata cacctccgcg
    19261 cgaaaacgcc gcggtctcct gtaggagcgc cggcaggcac gaaggcagcc ggcgagatgt
    19321 gcccccgcct caggccgtcc ccccaacccg ttcgcggctg ccgacgcccc attcgcggct
    19381 gccgccgctc ctacatgggg cggcaaccgt ggcggttctc tgtaggagcg ccggcaggcg
    19441 cgaatccgac gccggaacca tcgtctgccg gcctccagac acaccgtgca gccctcacac
    19501 ctcgagcgga tccacatcca gctgccagcg cagctcgcgc gcggtgcgct ggcggtagag
    19561 caccgcgacc caatcagcga gaaaggcctg cagcgggccg cgctggtcgg actccacgag
    19621 cagctgcgcg cgttcgcggc gggcgagccg ggtcatgcgc atcggcaccg gatcgtacag
    19681 ccgcaggccc tcgggcgcgc gctcctcggc gaggcggcgg gcgtggcgca ggaactcgac
    19741 ggcatcctcc agcgcggggg cgtccgcgcg cagcatggcc tggtgggtga agggcgggaa
    19801 gcccgcggcg cggcgctcct gcagggccat gcgggcgaag gcgtcgaagt cgtgcctggc
    19861 caggtgcagg tagagcgggt gcatcgggta ttcggtctgg atcagcacct cgccgggcaa
    19921 ctcgccgcga cccgcccggc cgccgacctg catcagctgc tggaacaggc gctctggggc
    19981 gcggaagtcc gcggcgtgca gcgaggcgtc cgcccccacc accccgacca gggtgagcct
    20041 ggggaagtcg tgccccttgg ccatcatctg cgtgccgacg aggaggtcgg cgtcgccggc
    20101 ggcgatggtg tcgagcagct tctcccactg gctgcgcgtg cgcgccgcgt cacgatccac
    20161 gcgcaacacg cgcgcctgcg ggaagagctc ggcaaggcgt gcctcgatgc gctgggtgcc
    20221 gcggccgaag ggctggatat cctggttgcc gcagctcggg caggcatgcg ggatcggccc
    20281 atcgcagcca cagtggtgac agcgcaggcg gcggtcggcg aggtgcacca cgaggttggc
    20341 cgagcaatgc gggcagcggc tcacccagcc gcaggacgga cacgacagca ccggcgcgta
    20401 gccgcgacgg ttgaggaaga ccaggctctg ctcgccgcgc tccaggcgct gcgcgatggc
    20461 ggcgtgcagc gccgggctga ggccctcgtc gagcttgatg cggcgcgtgt cgatgcagcg
    20521 caccgccggc agcgtcgccg cgaccgcacg ccggctcagg gtctgcagcg cgtagcgctc
    20581 gctttttgcg tggtgccagg tctccagcga gggcgtggcc gagccgagca ccaccggcac
    20641 gtcgcgctgg cgcgcgcgcc acaccgcgac gtcgcgcgcc gaatagcgca ccccctcctg
    20701 ctgcttgtac gaggcgtcgt gctcctcgtc gaccaggatc aggcccagcc gcggcagcgg
    20761 cgcgaacacg gcgaggcggg tgccgagcac gatgtcggca cgaccgctga gcgcctgcac
    20821 gaagccgcgc gagcgcgcac cgtcggcgag cgcggaatgc aggctgacca cgttggccgc
    20881 ggcgaagcgc tgggccacgc gctgctcgag ctgcggcgtg agcgcgatct ccggcaccag
    20941 catcagcacc tggcggccct gcgcgagcgc atgcgcggcg aggcgcagat agacctcggt
    21001 cttgccgctg ccggtgacgc catgcagcag ccacggccgg aagcgcatgc cggcgccgac
    21061 gatcacctcc accgcggcgg cctgctccgg cgtggccagc ggctgcgcgc ccgcctcatg
    21121 gcgcgcgcca ggatcggcga cgatctccag ccagccgcgc cgcaacagct cgcctacggc
    21181 ctcgccaccg tcgcgggcgc ggatcacgct gcgccgccac ggccccgccc cctcggcgag
    21241 tgcctgcagc aaggtcagcg cccggctcgc ccgtctcccg ggggcaagcg cctcgcgccc
    21301 ctccgcagtg atgcccagca acggatcctc gtcctcgtcg ctgaccccgt cggcacgacg
    21361 cagccccggc ggcagcgcga gcgcgacgac ctcgccgagc ggcgcgtggt aatagcgcgc
    21421 gacgaagccg accagttcca gccagtccgc aggcagcggc ggcacaccac gctggatgtg
    21481 cagcacggcc ttgagacgcg cggcctccac tgcggcctcg tccccgaggc cgacgatcaa
    21541 gccggtgcgc tcaccgcgcc cgaaaggcac cttcacgcag cgcccgacgt cctccgcgcc
    21601 cgcatcctcg gcggtgtaat cgaagacttg cgggagcggg accggcaggg cgacacggac
    21661 gatggccatg gggcagcgca ggctgaataa aaaccgcttc aagctcagta gcttgtgcga
    21721 tttcgatgag aacgggccga ggaaacgccg ggcaagtggc tggccgcaaa tggggctttc
    21781 ggcttgtcca caaaacctgt ggataagttt gtgggaaagc tgggtgaatc gggctcaaac
    21841 ctgcgccgcg taagggtttt cgtcacaatg ccttaacatt gcgcgaattt tttccctttt
    21901 attttcaacg gcttaaagaa atctcgggat agagccccat ttcgggccaa atccgcgggc
    21961 aggaaccgca gaatgtgcat aagtcaagcc cgaaaaacac gatttcgcgc ttgacaggcg
    22021 ggggcggaag cctgtcctgc accgcccgcc cccggtaagc ctcaagcgcc ggcgcggatc
    22081 gcccggctgt gcgcgtgcac ggtgtcgacc agcacgctca cgctctccgg cggggtgtat
    22141 tgcgagatgc cgtgaccgag gttgaagacg tggcccgggt ggttgccgaa cgcgtccagc
    22201 acccggcgcg tctccgtcgc gaccgcctcg ggcggggcga acagcacgtt ggggtcgagg
    22261 ttgccttgca gcgccacctt gtcgcccacg aggcgccgcg cacggccgat gtccatggtc
    22321 cagtcgaggc cgaccgcgtc gcaaccgatc gcggcgatcg actccagcca caggccgcca
    22381 cccttggtga atacgatgct gggcacacgc tggccgtcgc gctcacggat caggccggca
    22441 acgacctgct cgaggtagcg cagcgagaac tccttgtacg ccgcctcgga cagcacgcca
    22501 ccccaggagt cgaacaccat caccgcctgg gcgccggcct cgatctgggc gttgaggtac
    22561 ttcaccaccg cctgtgcggt gacgtcgagg atgtggtgca tcaggtcggg acggctgtag
    22621 gccagcgact tgaccttgcg gtagtcgtcg gaggagccgc cttccaccat gtagcaggcc
    22681 agcgtccacg gactgccgga gaagccgatc agcggcacgc tgccgtcgag cgcgcggcgg
    22741 atctcggcga ccgcgtccat cacgtactgc agctcggcgt ggggatccgg cgcgctgagg
    22801 ttgcggatct cccactcgtc cctgagcggg cgctcgaagc gcgggccctc gccctcggcg
    22861 aagtacaggc cgagccccat cgcgtcgggc acggtgagga tgtccgagaa caggatcgcg
    22921 gcgtcgagat cgtagcgcgc gagcggctgc agggtgacct cgcaggccat cgccggactc
    22981 ttgcacagct gcaggaagct tccggcgcgc ttgcgcgtct cgcagtattc ggggaggtag
    23041 cgaccggcct ggcgcatcag ccagacgggc gtgtattcgg ttggctggcg cagcagggcg
    23101 cgcaggaagg tgtcgttctt caggcggctc acgtcgagtc ctctatcggg gcgttcatgc
    23161 acaaggcggg attatcgcct gtccgggccc cgaacgggct tgtcgtcggt caagcagcgg
    23221 cggcacctcc gctcagcgcc gccagaacgt gggggtgagc acgaccagga aggtgaagat
    23281 ctccaggcgg ccgaggatca tcgcgaagca cagcacccac ttgtggaagt cgccgagcgc
    23341 ctggtagttc gacgccgggc cgaccagacc cagccccggg ccggtgttgt tgaggcaggc
    23401 cacgaccgcc gaaaaggccg tcaccagctc caggccggcg gccgacagca cgagggtcag
    23461 gctgacgatg ctgaccatgt acatgaagct gaaaccgagt accgcgtgca ggatgttctc
    23521 gggcaccggg ttcctgccca tgcgcaccgg cctcaccgcg ttcgggtgca gcgagcgcac
    23581 gatctcgcgg aacacctgct tgtagaggat catcgcgcgc atcatcttga tgccgccgcc
    23641 ggtggaaccc gaacaggcga cgaagctgcc gaggaagagg atccagatct gcgcgaacat
    23701 cggccacagc gtgtagtcgt gggtggcaag cccgagcgag gtcgagatcg acacgacgtg
    23761 gaaagccacg tagcgcaggg cctcgccgac atcggagaac acgccctggg cgagcaggta
    23821 cacggtgagc atgcccgtcg acagcgcgag cacaccgaag tagaagggga tctcggggtc
    23881 gcgccgataa ggcgccgagg atcgcctcac cagcgcgaga tagtgcgtgg cgtagttgag
    23941 cccggccagc agcgcgaaac cgatcgtgac cagctcgacg cccacactgt cgaaatgacc
    24001 gagcgaggcg tcgcggttgg agaagccgcc caggccggcg acggagaacg cgtggatcac
    24061 cgcatcccac ggttccagcc cgacccacca caggctgaag ccgcaggaca ccgtcagcag
    24121 cacgtaggtc agccacagcc ccttcgccgt ctccgcgatg cgaggggtga ggctggagtc
    24181 cttcatcggc gtcggcacct cggccttgta gagctggcgg ccgccgatgc ccagcagcgg
    24241 caggatggcg accaccagca cgatcacccc catgccgccg acccagtgca tgaaggtgcg
    24301 ccacaggttg atcgagatcg gcaggtgctc gagccccgtc agcacggtgg cgccggtcgc
    24361 ggtcaggccg gacaccgcct cgaagtaggc gtcggtgaag ccgagctcgg ggatataggc
    24421 caacagcggc agcgcgccga acagcggcag caccacccag gtcgccgcca ccagcaggaa
    24481 gccgtcatgc acccgcaggt cgcgccgctt gctgcgcgtc gccgcccaca gcagcaggcc
    24541 ggcgacgaag gtcacgaaca ggccctggtc gtaggccagg gtcgcaccgt cgcccagcac
    24601 ggccgacacg atgagcggaa agctcatcag caggccgaag atcatgatga tcaggccgag
    24661 ggcgttgagc gcagggtagt acgcgcgggt gcgggcgtcg gacgacatgt cagaggaagt
    24721 ggaacccgac ctggaacagc ttctcgacct tctgcaccag cttcttgttg gtacagaaca
    24781 cgatcacgtg gtcatcctcg cggatcacgg tgtcgtggtg cgggatgatc acctcgcgcc
    24841 ggatcaccct gccctcctcg ttgcgctcgt cacgcaccac cgcgccgatg ctcgcaccgc
    24901 gcggcagcgg gatatgctcg atcgggcgtc cgaccacctt ggagtccttg ctgctgccgt
    24961 gggcgatgat ctccagcgcc tcggcggcgc cacggcgcag gctatgcacc gcgaccacgt
    25021 cgccgcgccg cacgtgggcc agcagcgttc cgatcgaggt gtgcgcgggc gagatcgcga
    25081 tgtcgatcgg gccgccctgg accaggtcga cgtagctctt gcggttgatg agtgcgagcg
    25141 tgcggcgtgc gcccatgcgc ttggcgagcg aggcggacat gatgttgtcc tcctcgtcgt
    25201 tggtcagcgc gacgaagagg tcggtctcgt cgatgccctc ggtctcgagc agcttctcgt
    25261 cggtcgagtc gccgcgcaga acgagggcgt gcgagagctg ggaggcgagc atctcggcgc
    25321 gcgtgcggtt gagctcgagg atcttgacgt ggtggttctc ctcgatcgac tgcgccaggc
    25381 ggaaaccgat gttgccgccc ccggcgatca tgatccgccg catcggccgg tcggaacgcc
    25441 gcagctcgcg catgacctgg cggatgtgca ccgtggcggc gaggcagaac acctcgtcac
    25501 ccggcaggat gatggtgtcg ccctcgggca tgatcggctc gccgttgcga tagatcgccg
    25561 cgatgcgcac ctcgacgttg ggcaggtgga agcgcagcgc cttgagcgga tggccgacca
    25621 gcggtccgcc ctcgaaggcg cgcacgcaga tcaggctcac cacgccgtcg gcgaactcca
    25681 gtacctgcag cgcctcgggg aaggcgatca ggcgcttgat gtagtcggtg acgacctgct
    25741 cgggacagat ggagaaatcg accgcgaagt tgtcgtcgtc gagcaactcg ggatggtcga
    25801 cgtagtcggt cgagcgcagg cgcgcgatcc gcgtcggcag gttgaacagc gccttggcga
    25861 tgcgacaggc gcacaggttc gtctggtcgg actgggtcac cgcgatgagc aggtcggcat
    25921 cgtcggcgcc ggcctcgcgc agcacccgcg gcgaggcgcc gttgccgcat acggtgcgga
    25981 tctcgaggcg ttcgcgcagc gcgccgagat actcctcgct ggtgtcgacc agggtgatgt
    26041 cgttcgcttc ggagacgagg ttctcggcca ccgaggcgcc gacctggcct gcacccagaa
    26101 tgatgatctt caacgctgta tccggaagtg tccaagccgt cgattctacg ccccccaccc
    26161 ggcccggcaa acgctgacgt tgcgccgcag caacccccgg atgccagggc ccggactcag
    26221 ccggtcgggc cacccaggcg cgatgcgctc acgccgatcg gagcacggag ggccgcagtc
    26281 ggacagaagc gagccgcgtg gcggcagcct gcacccgcga cctgctgcgc gggtgcggga
    26341 ggcccccggc gcgctcagga ctcctcgtgc cgccgcccgg cctgcaggcc gagctgcttg
    26401 agcttgcggt acaggtgggt gcgctcaagg ccggtcttct ccgccaggcg cgtcatgttg
    26461 ccgccctcga ggcggaggtg gtgctcgaag tacatgcgct cgaaggcctc gcgcgcctcg
    26521 cgcagcggct ggtcgagcga caccccgcag gcgccggcgc cgagatccgg cggcagcagg
    26581 cgacgcacct cgccggcacc gatctcctcc tccagcgtgc cgagcgcgag cgacttcacc
    26641 gcggcgcgca gctcgggata gccgcccggc cacggcaggt tgcgcagctg gttgagcgcc
    26701 gcggtggaga agcgccgcag cggcacctcg ccggcctcca ccaggtgcag cagcatctgg
    26761 ctggcgagct cgggcagatc ctcgcgcacg tcggcgatcg acggcggcgc gaggctcacc
    26821 tcgaacaggc gggcgagcag gccctcctcc cagccctcgc ccaccagcgc ctccaggctg
    26881 cgctcggtgg cgaccaccag gcgcaggtcg tagcgctcga ggcggtcgag cgcgaaggcg
    26941 aggttcttct gctgcgcgcg cgaaaggcgg gcgagctcgc cgacgaagag cacgccgccc
    27001 tgggtagcct gcagctgggt gatgtcgagc ggcgcggtga cggcggcgag atcgagccag
    27061 ggcgcgttgg ccggctgcac gctgcgcgcg acgagctcgg cgagcgagcc cgcgccgacg
    27121 cgcagcaaca gcacgcgcga gctgccgacg atctgctcga gccggcgacg caactcgcgc
    27181 aagggcaccg agcgatggaa agcggcgagc gtgggcgccg actgcacgcc gggcgcctgc
    27241 gggcgttgca gcccgcgctt gaccgcggcg agcagcttct gcagcgcgat cggcttttcc
    27301 agatagtcga tcgcgccgat gcgggtggcc tcgaccgcgg tgtcgatcgt gccgtgtccc
    27361 gacatcatca ccaccggcat gttgagctgg ccgttggccg cccactcctt gagcagggtg
    27421 atgccgtcgg tgtcgggcat ccagatgtcg agcagcacca tgtcgggacg cacggcgttg
    27481 cgtgcggcgc gcgcggcggt cgcgttctcg gcgagcagga tgtcgtggcc ctcatcgcgg
    27541 aggatctccg agagcagttc gcggatgccg atttcgtcgt caacgatcag aatctttgcc
    27601 atttttcttc gtcatgcttc cttgttttcg gccagccgca ggcggatgcg cacctcggcg
    27661 ccaccaccct cgcggttgct caggcggacc tcgccgccgt gctcgtccac gatcttcttc
    27721 accatcgcca ggcccaggcc tgtaccacga gacttggtgg tgaaataggg ctcgaaggcg
    27781 cgcgacagga cctcggtggg gaagcccggg ccgttgtcgc ggaacagcag cagcgcgctc
    27841 tcgccgtcgc gacgggtgat caccgcgatc tccccttctt cctgcgcggc gagcgcgtcc
    27901 tgcgcatttt gcagcatgtt gtggatcacc tgccggatct gcgtcgcgtc accctggacc
    27961 ggaggcagcg tgctgcccaa ctcggtgcgg atctgcaccg cagcgctctc gtacagatgc
    28021 agcacctcac ggatcaggcc attgaggtcg agcggcgcga gctggggcgc aggcagtcga
    28081 gcgtagtcgc ggaaggcatt caccaggttc ttcatcgcct cgacctggtt cacgatcgtg
    28141 ccggtcgcac gctccagcat ctcgcgcccg ctgtcgtcca ggcggtcggc gagcttgaag
    28201 gccaggcgct cggccgagag ctggatcggg gtgagcgggt tcttgatctc gtgggcgagc
    28261 cgacgcgcga cctcgcccca ggccgcggtg cgctgcgccg cgatcaggct ggagatgtcg
    28321 tcgaacacca ccaccaggcc gccaccggtg ctcgccggca ggcgagagcc gtggatcagc
    28381 agggtacgcg gcgggcggtc cttgagcgga agctccatct gcttctgcca gtcaccctcg
    28441 ttggcggtga agccttctcg caaggcctgc ccgagctccg cttgccgcgg ccaggcctcg
    28501 agcgggatgt cctcgaatcc ggcaaggtcg tcctcgagga tctgcagcgc gccatggttg
    28561 gccgcacgca gatggccgtc ggccgagaag gcgagcacgc cggtcgacag gttggccagg
    28621 accgattcga ggtaggcgcg cgcggcctcg acctcggcgc gattgcggtc ggcggcgccg
    28681 cgcgcctcct ggagctggcg ggtcatgcgg ttgaaggact gggtcaacac gccgagctcg
    28741 tcgtttgcgg gcaaggcctg gcgcgggctg aagtcaccct gcgcgaccgc ctgggtaccc
    28801 tcggccagga tcagcagcgg ctgcgccagc cggcgcgcga tcagcacggc gaccgcaagc
    28861 gcgcccagca gcgcgagcaa cagggtcagg ctcagcgtga cggtgtagat gcgcttgagc
    28921 ccgctgcggc cgagcgtcag ctgctggtac tcgcggtacg cctcctgcac ggcctcggca
    28981 ttgcggccaa aggactccgg aaccggctgc tggagcatca gcaggttggc ttctccagcc
    29041 agcgtgcgca acggaatcgg ggtgagcacg cggatcacca gccgaccgtc gggctcggcg
    29101 atcacggaat ggaagtggcg actctggcgg gcctggcgga gctccgccgt gcccggcaga
    29161 tcgggaagca acgtacgccc ggactccgcg gcggtggcca ggacttgtcc gcccggcgcg
    29221 aggatggtag cgctggagat gccggcctgc tcgcgcaggc ggttcagccg ggtgcccgct
    29281 ccctgccctg ccccctcgag ttcgagcacc atgtcgtcgg acttgtcgcg tacctggctc
    29341 accaggtagt cgagcgcgtt ctgtccgagc gcgatgccgc cctcgagcgc cgaatccacc
    29401 cgcacgtcga accaggactc gatgctgcgc accacgaact gcagggacac gccgtagatc
    29461 accaacccag gcaccacccc catgagcgcg aacatcagca ccaggcgcat cttcagccga
    29521 gagccgaact ggccctcgcg gtgctcgcgc accagacggt gcagctgcat gccgaccagg
    29581 gctgcgagca ccaccgccat gccgccgttg agggcgagca gccagggata gctggtcgcg
    29641 aacagggtgg tgttggagct cgcggaggtg agcaggaaca gcgagatccc cgccaacgca
    29701 gctgcgacga cgagcaggac gcgcttcatc ggaaccccgg cgcgcccgga aggaaggtcc
    29761 agcgcaccca gtcggtctcg acgttccagt cgctgctgcc gatcgcagtg acctggaagg
    29821 gcttgggcaa ctggctggtg tcgagccgga agcgcagcga gacctcgtgc gagacgccgg
    29881 cctgcagcac gtcggtctcc gccaccagcc agttgcgcac gcgctgcatg gtgcgcagcg
    29941 ccgcgtcgag ctcgtcgaaa ttctgatgca ggttgccgac cgagagccgg tagctgcggg
    30001 tgatggcgtg gtagtagagg cggtagtcga ggctgcggcg cgccaccgtc tcgttgagcc
    30061 agtaccagcg cggacgctcg atcaccacct cggtggtgaa gtacagcgag accccgcgcg
    30121 tgaccgcgtc gatcaggcgc ggattgagat cgatctcgat gtcggcgttg agcacgtagc
    30181 cgccgtcccc gggcacgatc tcggcgctgc ggatgacgct ttcggcgtgc gcgagcaacg
    30241 cgaacagcgc gaacagcacg ccgacgacga agcggacggc gcgctcaggg ccgcttgcgg
    30301 aggagcgcgt aatagaagcc gtcatggtcg gcacaaggca gcagctgcag gtctggattt
    30361 ccacgaatcg ggagacgctc ggcatccgca tggcgaaggc agaagcgcgc gatctggccg
    30421 gcgttctcct cgtcgaacac cgagcaggtg acgtagagca ttgtgccacc cggggcgagc
    30481 gtgcgccaaa ggacctccag tatttcggcc tgctgtgcgg cgaagttggc aatatcggtg
    30541 tcacgacgca gccacttgat gtcgggatgg cggcgcacca cgccggaggc cgagcacggc
    30601 acgtcggcga ggatgcggtc gaagggccgg ccatcccacc aggaggcgag gcgccggcag
    30661 tcggcgacct tcagttcggc acgcaggccg aggcgggcga ggttgcgctc cacgcgcccg
    30721 gcccgcacgg ggtccagttc cagcgcaagc agctccgctg cagcgcgctc caggatgtgt
    30781 gcggtctttc caccgggagc ggagcaggcg tcgagcacgc gctcgccgtc ctgtgcgccg
    30841 agcaggtgag ccgcccactg cgcgccagcg tcctgcaccg agagtcggcc ttcggcatgg
    30901 ccaactagcc gggcaaccgc cagcgggcgg ccgagcagca gcgcgtcgtt atcgaggcgg
    30961 cggaattcca gccccgcctc ggcaagctcg gcctcgaccg cgggcagcgt ggcccggcgc
    31021 gaattgaccc gcagggccat gggcgggcgg gtattgcctg ccgcgaggac ctcctgccag
    31081 acctgcggat aggagcggtg cacacgcgcc acccaccagg ccggaaaggc gtggcgcgca
    31141 tccggcgcgg cctcgatcca gccctgccac tccggctgtc ggcgcagcgc attacgcagc
    31201 acgccattga ccaggttgcg caggcccggc atcgccaccg ccgcggcacc gacggcctgg
    31261 tcgaccacgg tgtgcgcctg ttccgggcgc tgcgtcaggc gctgcagggc gaccagcaga
    31321 agcgcccgaa tctcgaccgg cggcggactg tgcagcaacc gggcgaggat cgcgtcaccg
    31381 cgcccgtagt cgcgcaaggt ggaccaggcc agatcgcgca ccgcgccgcg cgtggcttcg
    31441 ggccattcgg ggtgctcggc cagcaggcgc tcgaaggcgt cggtcaggtt ggcgccagcg
    31501 atcacacccg caaccaatcc ggcagcccgt gcgagggcat agccgaggct gtcgatgggc
    31561 tgttccggga cacgacgtgg cgcagaacgc accccgggcg cgcgcggacg cggcgagccg
    31621 ccgggccgcg cagcgggccg tcggtctttt ggggaaactg gtgtcaagat cgggagtgct
    31681 gcggtagagg cggcgcctgc tcaggcgagc aagacgcgca gatgattggg caaggcgaac
    31741 tgcgcacagt gtaccgcacc attgaagtgc tgaagctcgc ggatcgctcg cgtggccagc
    31801 cggcggtcaa cctcgccggc gtcgagcacg gccgggtcga gcgtgtcgga agcgcaggcc
    31861 atgccccaca ggctgccgta gagcgggata tagaggaagt aaggccgcac cttcgcgaac
    31921 acccggcgca ggcgggcgac cagttcgcgc acgcgctcgg gctggtaaac cggcgtgccg
    31981 atgtgcaggg tcagcgcccc gccctcggcg agcagggtct tgcaggccgc gaagaaatcg
    32041 gcagcgtaga gcgcctccgc cggtcccacc ggatcagtga ggtcgagcac gatgaggtcg
    32101 tagcgctcgc cggccgcggg gccgtcctca tgcacatact tcatgccgtc gcagatgcgg
    32161 acctccacgc gcggttcatc cagggcgccg tgatgcaccg cgcggagatg gcgccgcgag
    32221 agctcgacca ccttcgcgtc gagctcggcg atcacgatgc gctcgacgcc ggggtacttg
    32281 agcagctcgt ccgcagagcc tccatcccct ccgccgatga tcagcgcccg acgcaggccg
    32341 gggtgcgcca caccggggac gtggatgagg ttctcgtggt agtagaactc gtcacgctcc
    32401 gaggtcatga agcagccatc gaggcggaaa agcttgccga agcgtggcgt atcccagacc
    32461 tcgtaggtct gccactcgga atgtccaccc tcgagcagcc gcgcaccacg caggaaatag
    32521 cccgcatcct cgctgacgag ctccgcgagc accccttcgg gcagatcggg caggggctcg
    32581 gacatcgctc agacccccac cggcagccgg cctcgaacga cctcgtgcgc cacgatctcc
    32641 gccggcgcga gcacctcgat cacgcggcga aaaacctgcc gcgcacgggc gctgttgtcg
    32701 cgcgagaagt tgcacacgta cacatccagc gtcgcatcgc cggtctcggg ccaggtgtgg
    32761 atcgcgagat gcgattcggc cagcaccacc gtcccggtga cgcccgccgc ctcaccgtcg
    32821 gcgttctcga actggtagaa gtaggccccg agcggggtca gcccggcgtc gcgacattcg
    32881 cccacgcaaa gttcctcgag ggcggagcgg cgggtcaggg tgtcgtgcgc gccgcgacat
    32941 cgatagatgt cgccaatcag atgcagtccg ttcatatccc cagtttccca aggctgttcg
    33001 acgttgctat tttaccacac caccccgagc aacattcctg caaagacaat gcgtacgtcc
    33061 gcgccgcgcg acccgagcgc cttctgttcc acgtgaaaca taccctcagc gcaggaaggt
    33121 atcgtaggcc aggcggagga tcagcacggt caccacggca aggaacatcc tgcgcacgaa
    33181 tccggtgcca tgcttcagcg ccatgcgcga gccgaggatc gaaccggtca ggttgcacgc
    33241 tgccatgacc gccgcaagct tccacatcag ctccacgttc ccggcaaaaa aaccgatcgc
    33301 cgcgagattg gtcgcgacgt tgaggatctt ggccgacacc gatgcgcgca ggaaatccat
    33361 gccgagcagg cggatgaaca ggaagatcag gaagctgccc gtgccggggc cgaagaaacc
    33421 atcatagaag ccgatcgcac cgcccacgcc cagcgcgatc gccaccgaac gtccgccatg
    33481 ctccggctcc ttcgagaccg accccagatc cttgcgcagg aaggtgtaca ccgcaacgag
    33541 gacgagcaga gcaaggatca acgggcgcag gatcgccgga tccagatagg ccacagcctt
    33601 ggccccatac caggacccga cgagggcagc gagcgctcca ggccccgcga ccctccaggg
    33661 aatctccacc cgacggctgt actggatcgc cgcgctggtc gtgcctacga tgctcgccag
    33721 cttgttcgtg ccgaacagcg tggcgggcgc ggtactcggg aaggccgcaa agagcgctgg
    33781 caactggatc aggcctcccc caccgacgat ggaatcgacg aagccggcaa acagggcggc
    33841 gagtccgagc gcgagaaaga ggaattcggt gtccatgggt ggagtgtttc acgtggaaca
    33901 aaaagggcgc gccgcagcac gctcgaggca tggcggcgaa gcgcgcgttg gttcgtgtag
    33961 gagcgccggc aggcgcgaac gcggccccgc agccccgccg caatcaccgt agccgcctcc
    34021 cccagcgcag catctgtacc tgccggagct cctgcaggaa accactgcgc cgcaggggtt
    34081 cggcgactac ttgccgatgc agaagcgcga gaagatgacc ccgagcagat cgtctgcgct
    34141 gaattcgccg gtgatcgtcc cgagttcctc ctgcgccagg cgcagctcct cggcgaagag
    34201 ttcgagtgcg ccgagctggg tgcctgccgc ttccacatgc cggagcgcct cgcgcagcgc
    34261 gagcaggtga cgctcgcgcg cgaggatcac gtcctcgcca tgcgcatgcc agccggcgat
    34321 ccgcagcagc tcctggcgca ccagctcgac gccctccccg ctgcgcgcgg aaacctgcag
    34381 gcggacccgt ccgcccgcct cgacgcgccc tgggggtaag ccgacgaggt cgatcttgtt
    34441 cgccaccacg atgcgctcga ccccttgcgg caggctctcg tccagatcca cctcggtcgc
    34501 cacccccgcc tcaacgagat gcaggatcac gtcggcgcgc gcgatctcgc gccaagtgcg
    34561 ctcgatgccg atgcgctcga cccggtcctc tgtgtcgcgc aggccggcgg tgtcgatgat
    34621 gtgcagcgga atgccctcga tctggatcgt ctcgcgcagg gcgtcgcggg tggtgcccgc
    34681 gacgtcggtg acgatcgccc gctcctcgcc ggcaagctgg ttgagcaggc tcgacttgcc
    34741 gacgttgggt gcccccacca gcacgacgtt gagcccgctg cgcagcaacg caccctggcg
    34801 cgcgcggtcg agcacgccct cgagcgcctc gcggatgcct tcgaggcgcg gcatcgcgcg
    34861 tgcgcgctcg aggaagtcga tctcttcctc gggaaaatcc agcgtcgcct cgaccagcat
    34921 gcgcaggtcg atcagcgcat cggtgatgcg atggacctcc tcggagaact ggccggacag
    34981 cgagcgcact gccgagcgtg ccgccgccgc ggtggaggcc tcgatcagat cggccacgcc
    35041 ctcggcctgc gcgaggtcga gcttgccgtt gaggaaggca cggcgggtga attcgcccgg
    35101 ctcggccagg cgggcgccga gctgcaggca acgctcgagc agcatctgca tgacgaccgg
    35161 tccgccatga ccctgcagct cgatcacgtc ctcgccggtg aaggaggccg gcgcggcgaa
    35221 gtagaggagg acgccctcat cgatcggccg ctcatgctcg tcgaggaagc gggtgaagtg
    35281 cgcggtgcgc ggccgcgggg cgcggccgca caaggcgagg gcgaaggcgc cgaggccggc
    35341 gcccgagacg cggacgacac cgatgccgcc gcggcccggt gccgtcgcga tcgcggcgat
    35401 cgtgtcaggc gggcttgccg gccgactttc cactttcgat catccgcgtg atctgccact
    35461 gctgggcgat cgacaggcag ttgttgacca cccagtacag caccaggccg gacgggaacc
    35521 acaggaacat gaaggtgaag ataatcggca tcgccatcat gaccttggcc tggatcggat
    35581 ccggcggcgt cgggttgagc ttcatctgga tcagcatgga cacgcccatg atgatcggca
    35641 ggatgaagta cgggtccttg gccgagaggt cctggatcca gcccagccac ggcgcgtgac
    35701 gcatctcgac gctgccgagc agcacccagt acagcgcgat gaacaccggg atctgcacca
    35761 ggatgggcag gcagccgccg agcgggttga tcttctcggt gcggtagaga ttcatcatct
    35821 cctgctgcat cttggccttg tcgttgccgt acatctcctt catgcgctgc aggcgcgggc
    35881 cgaggacgcg catcttggcc atcgacttgt agctcgccgc cgacagcggg aagaagatcg
    35941 ccttgatcgc caccgtgacc aggatgatcg cccagcccca gttgccggtc aggttgtgga
    36001 accacgacag cacccagaac agcggcgcgg cgatcacggt cagccagccg tagtcgacca
    36061 ccaggtccag gcccggagcg atgccttcga gcttgtcctg ctcctgcggg ccggcgtaca
    36121 gacgggtgga aaccgtgccc tcggcgcccg gggcgatcga ggccaccggc aggatcacgc
    36181 cggcggagaa caggttgttg ccgagcgcgc gcgcgaagta ttcgcgctgc tcgccttcct
    36241 tgggcagcca ggcgcccacg aagtagtgct gcaccatcgc cacccagccg tcggccgcgg
    36301 tcttggggaa cttggcgtcg ccctcggtga tgtcggcgaa ctgcaccttc tggaacttgt
    36361 tggcgtcggt atagaaggcc gggccggtga aggtggtgac gccgaaggcc tcgacctgct
    36421 cggccgggtt gccgtcgcgg gtgagctgga aataagcgtg cggcgcgaac gcctggccgg
    36481 agccgttgcg gatctcgtag gccacgtcga tcaggtagct gccgcgggcg aagcgcatca
    36541 ccttggtgac ctgcacgccg ttgtgctcgg gcgcctgcag gcgcagctcc acggcgttct
    36601 cgccgtcctt caggcgcagc tcgccggccg gcagctggaa cagggtcttg tgcgtcggca
    36661 ggccctcgcc gatcaggccg gactgcgcgg cgtactggtg ccgcgtggtg ccgtcgtcga
    36721 gcaggacgaa gttgccgccc gcctcgccgc tcgccttgtg ctgcttgagc tcgaggcgaa
//
LOCUS       DAOTIN010000024        35415 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_1331_length_35415_cov_8.886114, whole genome shotgun sequence.
ACCESSION   DAOTIN010000024 DAOTIN010000000
VERSION     DAOTIN010000024.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 35415)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 35415)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35415
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1331_length_35415_cov_8.886114"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..153)
                     /locus_tag="P5537_05745"
     CDS             complement(<1..153)
                     /locus_tag="P5537_05745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HRV77580.1"
                     /translation="MNEPARAAAADLRPLVMHVLYSFDVGGLENGVVNLINRLPKDRF
                     RHAVVAL"
     gene            complement(150..1658)
                     /gene="xrtA"
                     /locus_tag="P5537_05750"
     CDS             complement(150..1658)
                     /gene="xrtA"
                     /locus_tag="P5537_05750"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004197 - cysteine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exosortase A"
                     /protein_id="HRV77581.1"
                     /translation="MTRISPAFPIVAGALTLTFLWVVAWYWPTATEVAGIWWRSDTFA
                     HGLIVLPAFAWLTWRARDRIGDLQPQPVAWMAVPILAAGLLWLLGSLVSVAAAQHFAL
                     FVMLVSAFVGVLGWKLSRILLFPLAFLFFGVPIGEFLLPTLMHYTAEFTVWALRLSGV
                     PVYQEGLFFIVPNGSWSVVEACSGIRYLIASLVVGALYAYLNYTSLKRRLLFMLVALA
                     MPVVANWVRAYIIVMLGYLSDNRIAAGVDHLIYGWVFFGVVIFLMFWVGSRWQEEPAP
                     VQPAPAQAEPTRWARVVPIALALAAFQPALALLDRPIDVFAVTLAAPAPAEGWTTALE
                     ERFAYVPHYAGARVQLRTVYRSEDHPAPVGLFAAWYIGQREGQEMIAWENGPASHVLG
                     DLQLVRSARAMTVAGVPVVENFISTPSGRVLTWHWYRLNDRELARDAEVKLRLAIDRL
                     TGRADESAVVVLSTPVAEAGAERARAHLEAFLAAHAGAIRATLEAPAASIPR"
     gene            complement(1655..2866)
                     /locus_tag="P5537_05755"
     CDS             complement(1655..2866)
                     /locus_tag="P5537_05755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03087 family PEP-CTERM/XrtA system
                     glycosyltransferase"
                     /protein_id="HRV77582.1"
                     /translation="MQDSRPPLLYLTHRIPYPPNKGDKLRSFNILRQLARTHRVWLGS
                     FVDHPDDRRHIPALRQWCEQTCVVPIEPGIRRVASLRGLLRGEALSLPYYRSPRLARW
                     VEQVVAENGIRSAVAFSGPMAQYLDVPGLSRRVVDFCDVDSAKWTQYAADRRWPMSWL
                     YRREGERLLDFERDAAATVDASLFVTEAEAALFRRAAPALASRVGVMQNGVDADFFSP
                     ANAGASPYPSGGPVLAFSGAMDYWPNIDAVTWFVGEILPIIRRTLPAVRFWIVGMNPA
                     PAVRALASADVFVTGTVADVRPYVAHADVVVAPLRIARGIQNKVLEAMSMARPVVVSA
                     ASAVGLAARDGIECAIVEGAEGTAGRVLELLADPARRARMGEAARTCVEARYSWQAHL
                     ALLDQLLSETA"
     gene            complement(2871..3923)
                     /locus_tag="P5537_05760"
     CDS             complement(2871..3923)
                     /locus_tag="P5537_05760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FemAB family PEP-CTERM system-associated
                     protein"
                     /protein_id="HRV77583.1"
                     /translation="MDRLPIVVNLLKGEDAPRWDDFVRRCPQATFFHLSAWRDLMEEV
                     FDHRTFYLYAERAGDIVGVLPLAEVRSRLFGHALVSLPFCVYGGIATAEDAGPETLHA
                     LESKAETLAQALGVQHLEYRNLQPRHEEWPRQAELYVTFRKEILPEVEANLLAIPRKQ
                     RAMVRKGIKNALVSEVDDTVDRFFALYADNVLRHGTPALPKRFFEQLKERFGEACEVL
                     TVSSPEGKPLSSVLSFYFRDEVLPYYAGDDLAARELAANDFKYWELMRRACERGCKVF
                     DYGRSKVGTGPYAFKKNWGFEPQPLSYEYRLYKRDSIPQNNPMNPKYRAFIALWKRLP
                     IGVANRLGPHIVRNLG"
     gene            complement(3949..4788)
                     /locus_tag="P5537_05765"
     CDS             complement(3949..4788)
                     /locus_tag="P5537_05765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3473 domain-containing protein"
                     /protein_id="HRV77584.1"
                     /translation="MAASIINAFTCDVEDYFQVSALAPHFPREQWDSVPCRVERNVDR
                     ILALLDGHGARGTFFTLGWLAERYPGLVRRIAAAGHEVASHGYAHQRASDLTPQAFTA
                     DIRLAKVILEDITGNAVTGYRAPSFSIGEANLWAHDCIADVGYRYSSSVYPVRHDHYG
                     IPDAPRFPWRLPNGLVEVPISTVHMLGRNWPAGGGGFFRLLPYALSRWQIARVNAADR
                     RPAIFYFHPWEIDPEQPRVTAATAKTRFRHYINLQHTEARLDRLLSDFSWGRADEVFR
                     DAA"
     gene            complement(4790..5956)
                     /gene="wecB"
                     /locus_tag="P5537_05770"
     CDS             complement(4790..5956)
                     /gene="wecB"
                     /locus_tag="P5537_05770"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HRV77585.1"
                     /translation="MNTNASTFAPVICIVGARPNYMKVAPIIRAFAAHNPPIRTLLVH
                     TGQHYDPAMKDRLFADLDLPEPDVNLAVGSGSHAVQTAEVMKRFEPVIDEHGARAVLV
                     VGDVNSTLACALVASKRHIPVVHVESGLRSNDRRMPEEINRILTDQISDVLYTTERSA
                     HDNLVREGIPAERAVFVGNVMIDSLRASLPRAVPADVLLAAAGLDASRIAGGYGVVTL
                     HRPSNVDSADTLGPIIDALRTVSEALPLVVALHPRTRNNLERFGMLDRLAGPGFLLLP
                     PQGYLEMLGLMSGARMVLTDSGGIQEETTALGVACVTIRENTERPITVEQGTNTLVGV
                     HPEAIVAAAREILATGGKAGRVPEYWDGRCAERIAAHLHDWLVEHEAVRAAPGG"
     gene            complement(5953..7047)
                     /locus_tag="P5537_05775"
     CDS             complement(5953..7047)
                     /locus_tag="P5537_05775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="XrtA-associated ATPase"
                     /protein_id="HRV77586.1"
                     /translation="MYETFFKLSGKPFQLNPDPAFFYGSRGHRRAMAYLEYGLHQSEG
                     FIVITGEVGAGKTTIVRSLLEQLDPAKVVAATIVSTQIDASDMLRMVAGAFGVPSRNL
                     DKAGLLLAIETYLVSLAAAGKRALLIIDEAQNLSAAAVEELRMLSNFQLEDHALLQSF
                     LVGQPEFREVMQRAEMQQLRQRVIASYHLGPLDLQETRGYIEHRLRHVGWNEDPRFEP
                     GSFNAIYGHTGGIPRTINTLCDRLLLAAYLGESHVVTEAQVREVIAELKEEFAPPRAR
                     PAPGMGRAVLAGAEPVAALPPVEALAVERLRVSPELANQVAGMAGNYDLQRIEARLAG
                     LEQSVSATLAVLNQLLQAVRRDAAPEEETR"
     gene            complement(7059..>7568)
                     /locus_tag="P5537_05780"
     CDS             complement(7059..>7568)
                     /locus_tag="P5537_05780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03016 family PEP-CTERM system-associated
                     outer membrane protein"
                     /protein_id="HRV77587.1"
                     /translation="ALTSLRPDLSELERSRLALEAYRNGSRDAVRSNAYYVQRSVGAS
                     WTIDGVRNTLTLSVQRSDRNSLDTLSGFRFGGELENYDRVSTRSASLSFSHRLSGFTT
                     LNAGYVHSKSTGSGSANDETTRSIARLGVSRRLGANTDGGLTYRHTRADGSDAYTENA
                     VTATLGMRF"
     assembly_gap    7569..7668
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<7669..8287)
                     /locus_tag="P5537_05785"
     CDS             complement(<7669..8287)
                     /locus_tag="P5537_05785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03016 family PEP-CTERM system-associated
                     outer membrane protein"
                     /protein_id="HRV77588.1"
                     /translation="MNAQLTWTDNVDVADADPQQDWVLEVSPGVSMVRESGRLRGGLD
                     LRLRSLNHVERTEENTTYLALNGRGSFEAIENSVFVDVDGSISRDNQSSFRGRLPGDA
                     LDYDEDNEVRVFSVAPRFVFPFGAAGQGQVSYRERWLDSGSSSEGSGGGSAGSSGLGD
                     QQSRTLGVGLSDPAALRLFGWGLDYSRSETRYDERATRDVEQEVAR"
     gene            complement(8385..9347)
                     /locus_tag="P5537_05790"
     CDS             complement(8385..9347)
                     /locus_tag="P5537_05790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XrtA-associated tyrosine autokinase"
                     /protein_id="HRV77589.1"
                     /translation="MSLIEKAAQRLDQLKQATAEPGDEPAELQPVPVAAPVEALTDEE
                     GASTPVARSSAPPLVQPQVRAAPVSRSVTIDLAMLHEKGLVTPDRPRSTIAEEFRVIK
                     RPLLRNVNEEGPARIDNANLIMITSALSGEGKTFNAINLAISMAMELDYTVLLVDADV
                     SRPSVFRQLGLAPERGLMDILSGEVDDLSDVLLRTNIEKLSLLPAGMPHSRATELLAS
                     ENMNRLLKQMATRYSDRIIVFDSPPLLLTTESRVLATHMGQVVVVVEAERTTHASIRQ
                     ALATIESCPVKMNVLNKSRRSGPGSYYGYGYGYGYGETPSENAA"
     gene            complement(9361..10905)
                     /locus_tag="P5537_05795"
     CDS             complement(9361..10905)
                     /locus_tag="P5537_05795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNVR domain-containing protein"
                     /protein_id="HRV77590.1"
                     /translation="MEELVTQITSYLRGMWRYRWWGMALAWIVGVVAGLVIYQMPDKY
                     ESSARVYVDTQSVLRPLMAGLAVQPNIDQQITMLSRTLISRPNVEKLINMADLDLGVN
                     TTEEREALITRLSRDLRIGSSDRNNLFMLSYADTRPERAQRVVQSLLSLFVESGLGGK
                     RQDADAARRFIEEQIQTYEQKLTEAENRVKEFRLRNMGVLGDGAQDYISQIGAMTAQL
                     QQAQLEQREAMNGRDALQRQLVGEEPVLLPQAPSQSAVSVPEIDGRIDVLRRSLDELL
                     LRYTDKHPDVTGTRRLIEELEAQKRTQVEAMQAAGGSQFGALDANPYFQQMKLALAQA
                     ESRVASLNARVAEFQSRLDQLRERARLVPEVEAELAQLNRDYAVHKTNYDALVARRES
                     ANIAVEMNTQTGVADFRVIDPPTLATKPSAPNRLLLIPVAGLIGLIAGFALTFLISQL
                     RPAVVDPRGLREVTGLPVLGTVSMLTTPERRSARRRGLLAFGAGLFAYVGMVAAAVVA
                     LQLIQG"
     gene            complement(10996..11625)
                     /locus_tag="P5537_05800"
     CDS             complement(10996..11625)
                     /locus_tag="P5537_05800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide export protein"
                     /protein_id="HRV77591.1"
                     /translation="MFSCVSGARFRAARCLLGVVVASSLVGCASSFPPAPPLAADAEY
                     SYVLGAGDSVNIVVWRNPELSMSVPIRPDGKITTPLVEDLVAQGKDTSTLARDIEKEL
                     AKFIREPVVTVIATSFSGPYSEQIRVVGEASEPRILPYNQKMTLLDVMIAVGGLTEFA
                     DGNSATILRTGEGNKQYSVRIKDLIKRGDVSANVEMRPGDVLIIPQSWF"
     gene            11872..12666
                     /locus_tag="P5537_05805"
     CDS             11872..12666
                     /locus_tag="P5537_05805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77592.1"
                     /translation="MRHTTAVRGDHARFPTSKLVYFPTTGRDAINESSPLLDPDLPDL
                     SALLQDLSFERNGYEIRVASGSDCLKRRAAKLIERMYSSRGLFPYGTMAEIDKRDVTV
                     VALCGDDAVATLTVRMDFGNGLLADTLYSKEIDSARAIGGKVCEITQLALDPSSGNHD
                     ALAGLFQALYVIAQLTRRMTDIFIEVHPRHANFYQRIFGFKRIGGERICPRVGAPAVL
                     LHLSQDEFERALARHERIEQRHNSRVSRLLPMKAHAQEVIEALSSR"
     gene            complement(12692..14059)
                     /locus_tag="P5537_05810"
     CDS             complement(12692..14059)
                     /locus_tag="P5537_05810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77593.1"
                     /translation="MAADAAPDVPEAALADEAAAADLPDDAPAADADLDAASDADLDA
                     LLDVGTPAAGSEAATGIKWGGYAELGMAYTYRDPERWSHLRARGELTGSGQVAPRVRW
                     KLNARAELDGAFDLEDEHYPAAVRRDQRRDLMLREAYVDVGHGDWEFRFGRQHVVWGE
                     MVGFFFADVVSARDMRDFLQTELERMRIGQWAVRAERFGADTHFELLWVPKPSFDQIG
                     KPGSDFYTYPWMPADTVVSEDRPGGDIDDGNWGARISHLVDGWDLSAFYYHSYDVAPT
                     LHAYAPGRAELRHERIDQVGGTFSKDLGSFVLKGEAVHTSGRSVNTFARAGNLPVVGL
                     VGTDMVDYAFGVDLPSGDWRFNVQYYGRRLDDHRPAMMMDRHEQGVSLQIVHGTGTDL
                     EAEVLAVTSLNRSDYSLRPKLSWKFAPAWRATVGVDVFGGKGRGMFGVYDDRDRAWLE
                     LRRWF"
     assembly_gap    14077..14176
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(14313..15038)
                     /locus_tag="P5537_05815"
     CDS             complement(14313..15038)
                     /locus_tag="P5537_05815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV77594.1"
                     /translation="MSKSFRLGEQTVLALDDVSLEIEPGVFLAIAGPSGSGKSTLLNI
                     IGCIDTPTSGRVVVDGHDVSNRTPDELADLRARTIGFIFQTFNLLPVLSAAENVEYPL
                     LQMPELTRAERAERVRHYLGVVGLKKYAEHRPNQLSGGQRQRVAIARALATHSKVVLA
                     DEPTANLDSKTGTSILKLMRDINRQSGTTFVFSTHDRKVMNMADRLVRIADGQITALG
                     LRVDDRWVFVDGRTPRDEDIREI"
     gene            15106..15909
                     /locus_tag="P5537_05820"
     CDS             15106..15909
                     /locus_tag="P5537_05820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_process: GO:0042953 - lipoprotein transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein-sorting protein"
                     /protein_id="HRV77595.1"
                     /translation="MTPSLRSRRRFVACLAGSLMLPTLALATDAASPAEPAGAEGVDT
                     VAADLVRRADAIRFPRESFQTEIVVRNFADGAEGESRTFRVLSRGNENTIVLTLEPAT
                     ERGQALLMRARDLWVFMPSVSQPVRLSLAQRLTGQVANGDLARANLAGDYIPTVAGTE
                     TIEGQAAVVLDLKAVDRGVTYARVRYWVGERDSRPLKAEFYALSGRLLKTARYEEFRQ
                     MAGAVRPTRLVMEDALKKGEISVLTYENMNVRDLPERMFTREYLRRLQQ"
     gene            complement(15934..17343)
                     /locus_tag="P5537_05825"
     CDS             complement(15934..17343)
                     /locus_tag="P5537_05825"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HRV77596.1"
                     /translation="MNPTILHHGARNGVTGSCHQLFVEGRNSLLLDCGLFQGAETAPD
                     GRSAADRLEIDFPLEGVGALVLTHVHIDHCGRLPWLLAAGFKGPILCSEPSARLLPTV
                     LADAFAVGVSRDRALIERYLGKVEPRIRALPYGKWHLVYRSPDASCRIRLQRAGHILG
                     SAYVECELSGAAWPEPRRVVFSGDLGAPHAPLLPAPRPPWRADVLVLETTYGDRVHEN
                     RRDRRARLQAVVEHALQDGGTVIVPAFSIGRTQELLYEFEDILHRQRVRPGKHSAAWG
                     ALRIFLDSPLAQRFTALYRELQPFWDAEARARVRAGRQPLSYDQLVAIDSHEEHLANV
                     RRLARSREPAVVIAASGMCAGGRVVNYLREMLGDPRHDVLFVGYQARGTPGHAIQTYG
                     PRGGYVELDGERVDIRAGIHILSGYSAHADRDDLTRFVTRMRHLPGEVRLVHGEDAVR
                     AAFAGHLQGVVGERMRIVV"
     gene            complement(17741..>18663)
                     /locus_tag="P5537_05830"
     CDS             complement(17741..>18663)
                     /locus_tag="P5537_05830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HRV77597.1"
                     /translation="RAQAEKLARNQAPVFIHGESGTGKEVIARHIHALGARAGGPFVP
                     VNCGAISPELMESEFFGHRKGSFTGASADKSGLFQAASGGTLFLDEIGELPLAMQVKL
                     LRAIQERAVRPVGAHAEEPVDVRILSASHQDLGRLVAEGRFRQDLFFRINVITLRVPP
                     LRERREDIPDLASHILARLAVREGGAPRRLSTAALERLQAYDFPGNVRELENLLERAC
                     ALCEGEEIDVGDLGVEGDCSPLGATAGVEGGTAPVAEPEEGREGQDEVERLRIIRALE
                     QTRWNRSAAARMLGMTLRQLRYRLQKWGME"
     assembly_gap    18664..18763
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<18764..19287)
                     /locus_tag="P5537_05835"
     CDS             complement(<18764..19287)
                     /locus_tag="P5537_05835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV77598.1"
                     /translation="MTQVERRNRPRSTDVLVVDDEDDIRELLELSLMRMGLACDTAGS
                     VGEARALLAERGYRLCLTDMRLPDGDGLELVEYIQTVRPGLPVAVITAFGSIETAIRA
                     LKLGAFDFVTKPVELKALRELVQHALKLREGGSEEHPAATAERSLIGHSAAFVQLRAQ
                     AEKLARNQAPVFIHG"
     gene            complement(19284..20879)
                     /locus_tag="P5537_05840"
     CDS             complement(19284..20879)
                     /locus_tag="P5537_05840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HRV77599.1"
                     /translation="MPAHDPIEAAAFAVDSADRARQRALRYLNVFRLILGGLFLVAGE
                     EFGLGSESPRLYLAAVVGYLTAVLTLGFPDAVRRLGFERVVILLALADIVALAAIMWV
                     SGGYRSGMPVLMMVMLAGAGLIGEGRMVMFSAALATLAVLAENASRLFGGGKSVEFLQ
                     VGIFCAGFFGIAAIARLLALRAQANAALAAERGVALAKQQAVSAHILRDMQDGVIVVG
                     ARGRVLHANAQALEMLGLARAGGEALDGLALADLDAGLEGMLQPAVGEEGRLMRLGAA
                     GRLLRCRRVQGDAGSAAEGDTLLYLTDYEEIQRQLQQIKLAALGRLTASMAHEIRNPL
                     SAVTQAAELLGEEKRADMQARLVRIINDNARRIERMIRDVLALGRREQALPEALPLAA
                     FVREILDARVFREPAEAQLYELAIDPALTLAMDRAHLHQILDNLLSNAARHASGKAGA
                     VRLWAEPLPHAKVVLHVQDDGPGFDEAMRAHLFEPFFTTHPKGTGLGLYIARELAEAN
                     DATLALAPGGPGADFILTASQQP"
     gene            complement(20857..21144)
                     /locus_tag="P5537_05845"
     CDS             complement(20857..21144)
                     /locus_tag="P5537_05845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PP0621 family protein"
                     /protein_id="HRV77600.1"
                     /translation="MLEFWRSRLSSGPNVRNLLLLILVVFGIWWARAAVRRLKARGGL
                     GRKAEDARLAKSEPMRECRHCGLIVPESEGVRAGESFYCCDEHRRAGPRPD"
     gene            21257..22414
                     /locus_tag="P5537_05850"
     CDS             21257..22414
                     /locus_tag="P5537_05850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HRV77601.1"
                     /translation="MPHFPAPIESRLPNVGTTIFTVMSRLAQECGAINLSQGFPDFNA
                     EDLLFERVAHWMRAGHNQYAPMAGTAALRAAIAAKVEALYGTAYDPEHEITVTAGATQ
                     ALFTAVTACVHPGDEVIVFEPVYDSYVPAIELAGGKVVRMRLAAPDYRPDWDAVAAAI
                     GPRTRMIMINTPHNPTATVWTRDDLDRLAALVRGTGIVVVADEVYEHIVFDGAAHASC
                     AAHPALAQRSFVVSSFGKTYHITGWKVGYVLAPRELMAEFRKVHQFNVFTVNTPVQLA
                     LADYMADASRHLGLAAFYQAKRDFFRAALAASRFELLPSHGTYFQLARYAAISDLGDA
                     AFCEHLTRDVGVAAIPVSAFFADGRDEHVIRFCFAKNEATLAAACARLAAL"
     gene            22474..23544
                     /gene="mtnA"
                     /locus_tag="P5537_05855"
     CDS             22474..23544
                     /gene="mtnA"
                     /locus_tag="P5537_05855"
                     /EC_number="5.3.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046523 -
                     S-methyl-5-thioribose-1-phosphate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-methyl-5-thioribose-1-phosphate isomerase"
                     /protein_id="HRV77602.1"
                     /translation="MFEQPIPTLQRDGGTVRILDQTLLPFRTETVALRTLAEAAHAIR
                     SMQVRGAPLIGATAAFGVALALADEGADDAALARALATLGATRPTAVNLHWALERMRR
                     ALQPLPPGARVEAAWAEAEAIRTDDAATCDAIGRHGVRLIREIAARRPGPVRLMTHCN
                     AGWLATCGAGTALAPVYAAQAEGIAVEVVVSETRPRNQGLLTAWELRAAGVPHLLIAD
                     NAAGLLLMRHEVDLVITGADRIAANGDTANKVGTYLKALAARVAEVPFHIAAPHSTLD
                     FACADGAAIPIEDRGADEILHVRGEAADGATAELALAPAGTRAANPAFDLTPAALITG
                     IVTERGIARPGELARLYPEQAR"
     gene            23541..24230
                     /locus_tag="P5537_05860"
     CDS             23541..24230
                     /locus_tag="P5537_05860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HRV77603.1"
                     /translation="MSAGTPGCIHEEAGWRGEDDPRARLLHTLRAMGAARLNVGTSGN
                     ASQRLAGGRMLISPSGIAAERCRAEDMVVVEADGRYAGARAPSSEWQLHHDVYAAFPA
                     AGAVLHAHAPFATALACQRLDIQPFHYMIARFGGTTVRCARYATFGTQALSEATVAAL
                     HERSACLLANHGMVVFGRDLEHALAMAVEFETLCEQYWRTLQLGAPVLLSEAEMAEVI
                     ERFKWYGKPRA"
     gene            complement(24287..25147)
                     /locus_tag="P5537_05865"
     CDS             complement(24287..25147)
                     /locus_tag="P5537_05865"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HRV77604.1"
                     /translation="MRVGFIGLGVMGEPMARHLRAAGHALAVWARRPQSAAALVAEGV
                     PLCATPAELAARSEVVITIVTASADVEALAFGAQGLAEGFVPGAIHVDMSTIAPATAR
                     ALAERYAARGVGWVDAPVSGGGQGARDATLAIMAGAEDDMLERVRPLLGALGKRIVHI
                     GPPGAGQVAKACNQMIMVSAIQACAEAFRLAGAHGVDKAAVLRALAGGSAGSRVLEVM
                     GAKMVARDFAAGVEARLHHKDFAILMEEAARLGAPLPVAAQVWQQLDALMGAGWGRDD
                     TASLLRVLEG"
     gene            complement(25180..26061)
                     /locus_tag="P5537_05870"
     CDS             complement(25180..26061)
                     /locus_tag="P5537_05870"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004332328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HRV77605.1"
                     /translation="MEVGFIGLGLMGRPMALNLLAAGHRVHVWSRRRESMRPLLDAGA
                     SDCASAAEVARRAAVTISMVSDAPDVEQVTLGADGIADGAGAGHVHIDMSTIAPAAAQ
                     SIAAGLAERGIVALDAPVSGGEPGAIAGTLTIMVGGDEGACARVQPLFEAMGKSITRI
                     GEAGAGQVAKACNQIITGVGVAAVAEALNFAARSGADGTKVREALLGGFAYSRILENH
                     GQRMLERNFRPGFKAWMHQKDLRIVMGEAHRLGVALPAAAATAQLFNGMIGCGMGEDD
                     SVAMLKLLERMSGGVGA"
     gene            26242..27156
                     /gene="ybiB"
                     /locus_tag="P5537_05875"
     CDS             26242..27156
                     /gene="ybiB"
                     /locus_tag="P5537_05875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein YbiB"
                     /protein_id="HRV77606.1"
                     /translation="MKYGPIIKEIGRGAKGARDLDTAAAAALFGDILDGVVPELELGA
                     ILLAFRIKSEALPELLGFKQAMDARTAQVAVPDGPRCVVLPTYNGARRQANLMPLVAL
                     LLAREGVPVLIQGRHDFETRVSPFELLAALELHPATDAAEASAQLAQRRVACIGVDKL
                     LPGLDPLLALRVRMGVRASGHTMAKLIDPCRGRSVRVVAVTHPEYLERMDAFLRADGG
                     RAMLMRGTEGEIYANPRRCPEMKVYVEGEASVGVPAEEGGAPPLAGLPDAPSVADNAA
                     LIRSMLAGEVPVPGPILRQVAALRALAN"
     gene            complement(27344..28228)
                     /locus_tag="P5537_05880"
     CDS             complement(27344..28228)
                     /locus_tag="P5537_05880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pirin family protein"
                     /protein_id="HRV77607.1"
                     /translation="MSTTPAPRTPSAAVHHPRTVERLVTGHPTSDGAGVKLTRVLTQP
                     LQRRLDPFLMLDAFGSDQADDYIAGFPDHPHRGFETVTYMIAGRMLHRDSAGHEGLLE
                     NGGVQWMTAGRGVIHSEIPQQEEGVMEGFQLWLNLPAQDKMSAPWYRDFAAGELPRFT
                     TEDGVEATVIAGESHGVRGAVTRAVTAPLYLDLHLPCGTSFSQPLPAGHNAFVYVYRG
                     RVKLGEVEVPVRNMAILANAADRDGVRIEALEEARVLLIAGRPLGEPIAQYGPFVMNT
                     EQEIYQAVADYRAGRLAA"
     gene            complement(28339..28938)
                     /locus_tag="P5537_05885"
     CDS             complement(28339..28938)
                     /locus_tag="P5537_05885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HRV77608.1"
                     /translation="MNILQINGSARSQAGNSTRLANELVGRLVAGQPAARVVVRDLAR
                     DPAPAIDEAALGALFTPAERRSPDQAARVALSDALVAEVQAADVLVLGVPMYNFGIST
                     QLKNWIDAIARAGVTFRYTENGPEGLLKGKKAYVAFARGGRYRGTAADTQTPYLKTLL
                     GFLGITDVHFIYAEGLNMGEEATKQGFAEAEADIAAALA"
     gene            29034..29942
                     /locus_tag="P5537_05890"
     CDS             29034..29942
                     /locus_tag="P5537_05890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001216 - DNA-binding transcription
                     activator activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HRV77609.1"
                     /translation="MEQIDPNDLLVFARVVAEGSLTAAADKLGLPKSTVSRRLSRLEE
                     LLGERLLLRTTRRLNITEFGAALLDHARQLESEVEAVAALAESRQARPSGRLRVSMPS
                     DFANLLLTDMLAAFAALHPAVTLELDLSPRRVDLLGENFDLAIRLGDLPDDALLAARR
                     LAVFPWGLYAAPAYLAEHGEPRAPDDLHRHRALRLLARTGDAIRWNLRCGEQRWEGVP
                     PGSITANSPELLIRFACAGAGITTVPEYFAAPHVQRGELRRVLPDWHPPSIAAWAVFP
                     GRRLMPAKTRAFLDMLQAALGDERHG"
     gene            30060..30566
                     /locus_tag="P5537_05895"
     CDS             30060..30566
                     /locus_tag="P5537_05895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="disulfide bond formation protein B"
                     /protein_id="HRV77610.1"
                     /translation="MTLLHRLLNLPARVLYLALFLVATGLLSFGLYLQHGLGLEPCPM
                     CIMQRYAFATAALIALIAGLHSPGRSGERVYAALIGASSLTGGGIAARQSWMQIDPPL
                     IPECGPGLEFMLESFPLAQALPMIFRGAGDCTVVEWTFLGLSIANWSLVSFTATVLFA
                     GWMLLRRR"
     gene            complement(30574..30795)
                     /locus_tag="P5537_05900"
     CDS             complement(30574..30795)
                     /locus_tag="P5537_05900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2892 domain-containing protein"
                     /protein_id="HRV77611.1"
                     /translation="MTTNDYVRAFAGAFVLISLALGVEASPLFVSKHFLWVTGFVGLN
                     LFQSAFTGLCPLVNILHKLGVKDGPASCN"
     gene            complement(30792..34067)
                     /locus_tag="P5537_05905"
     CDS             complement(30792..34067)
                     /locus_tag="P5537_05905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HRV77612.1"
                     /translation="MDKPLGISGRIAAGFQRNAITPLLALVLLLAGIFATLITPKEEE
                     PQIDVTMANVLVPFPGASARDVEALVARPAEQVLSRIAGVEHVYTVSRPGMAVITVQF
                     EVGVPNQTALVRLYDTVDSHADWLSPQLGVGKPLIKPKGIDDVPIVSFTLWTPDPARA
                     AFSLQQVSRAIETELKRIPGTRDVATLGGPGHVIRVNMDIERMNAHGVTAQDLRGALQ
                     LANASQPAGSLVAGNREVLVQTGTYLESAEDVRRLVVGVQDRKPVFLRDVAEVVDGPD
                     QPSQYVWFGTGAAAEQRGIDEQGLFPAVTLALSKKPGANAADVAQAAMQRLENLRGSL
                     IPEGVEVTVTRDYGKTANDKANQLIGKLAFATAAVVALVFFALGRREAIIVGIAVTLT
                     LAATLFASWAWGFTLNRVSLFALIFSIGILVDDAIVVVENIHRWHTLEPDTPLWKLIP
                     KAVDEVGGPTILATFTVIAALLPMAFVTGLMGPYMSPIPINASMGMFISLVVAFVVTP
                     WLAQKMLKNVDAHQHGGEDRMTKRLDGLFRGVMTPMFDARRGGRNRLMLWLVVFALIG
                     ASVALPVVQLVVMKMLPFDNKSEFQVVLDMPVGTPVEDTARVLNEIGAHLATVPEVTD
                     WQSYAGAAAPINFNGLVRQYYLRSAPEQGDIQVNLVDKTARDRQSHEIAVSVRDAVTE
                     IARRNGGNAKVVEVPPGPPVLSPIVAEIYGPDYDGQVEVARRVRAAFEDTPDIVGVDD
                     TVDEDAPKLVLRVDQAKAARMGVAQADIVEVVRLGLSGENVTPVHGGDNKYEIPVRIQ
                     LPAVRQSDLADLLAMQVRARGGDNAGQLVKISEVVQVAETRREQILYRKDLLPVVYVT
                     GDMGGKLDSPLYGMFDIRSRVNGMALEGAQGLAGTLGEWFIRQPADPYAGYQLKWDGE
                     WQITYETFRDMGAAYAVGLVLIYLLVVAQFRSYLVPLIIMAPIPLTIVGVMPGHALLG
                     AQFTATSMIGMIALAGIIVRNSILLVDFVNQQVAEGMEFGEALIRAAAVRAKPIGLTA
                     LAAMIGAVFILDDPIFNGLAISLIFGIFVSTVLTLVVIPVLYYAAMRGRIASLKNPEE
                     NPA"
     gene            complement(34082..35161)
                     /locus_tag="P5537_05910"
     CDS             complement(34082..35161)
                     /locus_tag="P5537_05910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HRV77613.1"
                     /translation="MKPIMLPTPARIAAVLALSLFVATSGAARAEVPTVRIEARAVVP
                     VIAAEATVEAVRQSTLAAQMPGRILELSADAGDRVRKGALLARIDPAEAAAAVAAAEA
                     GIAQAESALANARAEYQRARSLVERKFLSQSALDNARAQFQAAEAQVRAARAQREQAA
                     TVKGYASVVSPLDGLVAARHIEPGEMAQPGRNLLTVYDPAQMRAVTDLAPQRLAELGA
                     GPLRASVELPASGRVIEAAAVTVLPAADARTHTVRVRVDLPAGVEDVLPGSFARVHFH
                     GAAAPAAAGPVVIPAAAVLRRGELTAVYAADGQGGFTLRQVRLGRALPGGESVEVLSG
                     LKGDETLALDPVQAGIQVRAAAAAR"
BASE COUNT         5383 a        12387 c        12222 g         5123 t
ORIGIN      
        1 caaagccacc acggcatgcc gaaaccgatc cttgggcagg cggttgatca ggttgaccac
       61 cccgttctcc agcccgccca cgtcgaagct gtaaagcacg tgcatcacca gggggcgcag
      121 atctgcagca gccgcgcgtg caggctcgtt catcgcggaa tgctcgccgc gggcgcctcg
      181 agcgttgccc ggatcgcccc ggcatgcgcg gccaggaaag cctcgaggtg tgccctcgcc
      241 cgctccgccc ccgcctcggc caccggggtg gacagcacca ccaccgcgga ctcgtccgcc
      301 ctgccggtga ggcgatcgat ggcgagccgc agcttcacct cggcgtcgcg cgcgagctcg
      361 cgatcgttca agcggtacca atgccaggta aggactctac ccgacggcgt ggagatgaag
      421 ttctcgacca cgggtacgcc ggccaccgtc atcgcacgcg cgctgcgcac cagctgcaga
      481 tcgcccagga catgggaggc ggggccgttc tcccacgcga tcatctcctg cccctcgcgc
      541 tggccgatgt accaggcggc gaacagaccg accggggctg ggtggtcctc gctccggtaa
      601 accgtccgca gctgcacgcg cgcgccggcg taatgcggga cgtaggcgaa gcgctcctcg
      661 agggccgtcg tccagccctc cgcaggcgca ggagcggcca acgtcaccgc gaacacgtcg
      721 atgggccgat ccagcaatgc aagcgccggc tggaacgcgg cgagcgccag cgcaatcggc
      781 accacccttg cccagcgcgt aggttcagcc tgggcgggtg ccggctgcac cggcgccggc
      841 tcctcctgcc agcggctgcc gacccagaac atcaggaaga tcaccacccc gaaaaacacc
      901 cagccgtaga tcaggtggtc caccccggcg gcgatgcgat tgtcggagag gtagccgagc
      961 atcacgatga tgtaggcgcg cacccagttg gccacgacgg gcatggccag cgccaccagc
     1021 atgaacagca gccgacgctt gagactggtg tagttgagat aggcatacag cgcaccgacc
     1081 accagcgagg cgatcaggta gcggatgccg ctgcacgcct ccaccaccga ccagctgccg
     1141 ttgggcacga tgaagaacag cccttcctga tacaccggca cgcccgacag gcgcagcgcc
     1201 cacacggtga attcggcggt gtagtgcatc agcgtgggca gcaggaactc gccgatcggt
     1261 acgccgaaga acaggaaggc gagcgggaac agcaggatgc ggctgagctt ccagcccagc
     1321 acgcccacga atgccgacac cagcatgacg aagagcgcga agtgctgtgc cgcggcgacg
     1381 ctcaccaggc taccgagcag ccaaagcagc cccgccgcaa ggatcggcac ggccatccag
     1441 gcgaccggct gcggctgcaa gtcgccgatg cgatcgcgcg cgcgccaggt cagccaggcg
     1501 aaggccggta gcacgatgag gccgtgcgcg aaggtgtcgg aacgccacca gatgcccgcg
     1561 acctcggtgg ccgtcggcca gtaccaggcg acgacccaca ggaaggtcag cgtgagcgcg
     1621 cccgcgacaa tcggaaaggc tggggagatg cgggtcatgc ggtttcactc aggagttgat
     1681 cgagcaacgc gaggtgggct tgccagctgt agcgtgcttc gacgcaggtg cgcgcagcct
     1741 cacccatcct ggcgcgtcgc gccgggtcgg caaggagctc gagaacgcgt cccgccgtcc
     1801 cctccgcccc ctcgacgatc gcgcactcga tcccgtcgcg cgcagccagg cccacggccg
     1861 atgcagccga aaccaccacc gggcgcgcca tcgacatcgc ctccagcacc ttgttctgga
     1921 tcccgcgcgc gatccgcagc ggcgccacga cgacgtccgc atgggcgacg tacggacgca
     1981 cgtccgcaac ggtgccggtt acgaagacgt cggcggatgc cagggcgcgt accgcgggcg
     2041 cagggttcat gcccacgatc cagaagcgca ccgcgggcag ggtgcggcgg atgatcggaa
     2101 ggatctcgcc gacgaaccag gtgaccgcgt cgatgttggg ccagtagtcc atcgccccgc
     2161 tgaacgcgag caccggcccg cctgatggat agggcgatgc gcccgcgttg gcgggtgaga
     2221 agaagtccgc atccacaccg ttctgcatca cccccacccg gctggcgagc gctggcgcgg
     2281 cacgccggaa cagcgccgcc tcggcctccg tgacgaagag gctggcatcc accgtggcag
     2341 cggcgtcgcg ctcgaagtca agcaggcgct cgccctcgcg ccggtacagc caggacatcg
     2401 gccagcgtcg gtcggcggcg tactgcgtcc atttggccga gtcgacgtcg cagaagtcga
     2461 ccacgcggcg gctcagcccg ggcacgtcga ggtactgcgc catcggcccg gagaaggcca
     2521 ccgccgagcg gatgccgttt tccgccacca cctgctccac ccagcgcgcc aggcgcgggc
     2581 tgcgatagta cggcaggctc agcgcctcgc cgcgcagcag gccgcgcagg ctggcgacgc
     2641 ggcggatgcc gggctcgatc gggaccacgc aggtctgctc gcaccactgg cgcagcgccg
     2701 ggatgtggcg gcgatcgtcc ggatggtcga cgaagctgcc cagccacacc cggtgcgtgc
     2761 gggcgagctg acgcaggatg ttgaaggacc gcagcttgtc gcccttgttg ggcggatagg
     2821 ggatgcggtg cgtcaggtag aggagcggcg gccggctgtc ctgcaccgcc ctaccccagg
     2881 ttgcgcacga tgtgcggccc gagccggttg gccacgccga tcggcaggcg cttccagagg
     2941 gcgatgaaag cccggtactt ggggttcatc gggttgttct gcgggatgct gtcgcgcttg
     3001 tacaggcggt attcgtagga cagcggctgc ggctcgaagc cccagttctt cttgaaggcg
     3061 taggggccgg tgccgacctt gctgcggccg tagtcgaaca ccttgcagcc gcgctcgcag
     3121 gcgcgccgca tcagctccca gtacttgaag tcgttggcgg cgagctcgcg cgcggcgagg
     3181 tcgtcaccgg cgtagtaggg cagcacctcg tcgcggaagt agaagctgag cacgctcgac
     3241 agcggcttgc cctcgggcga gctcaccgtg agcacctcgc aggcctcgcc gaagcgctcc
     3301 ttgagctgct cgaagaacct cttcggcagc gccggcgtgc cgtggcgcag cacgttgtcg
     3361 gcgtagaggg cgaagaagcg gtcgacagtg tcgtccacct cgctcaccaa cgcgttcttg
     3421 atgcccttgc gcaccatggc gcgctgcttg cgcgggatgg cgagcaggtt ggcctcgacc
     3481 tcgggcagaa tctccttgcg gaaggtgacg tagagctcgg cctggcgcgg ccactcttcg
     3541 tggcgcggct gcaggttgcg gtactcgagg tgctgcacgc cgagcgcctg cgccagtgtc
     3601 tcggccttgg actcgagcgc gtgcagggtc tcggggccgg cgtcctcggc ggtggcgatg
     3661 ccgccataga cgcagaaggg cagcgacacc agcgcatggc cgaacaggcg gctgcgcacc
     3721 tcggcgagcg gcagcacgcc gacgatgtcg cccgcgcgct cggcgtagag gtagaaggtg
     3781 cgatgatcga acacctcctc catgagatcg cgccaggctg acaggtggaa gaaggtcgcc
     3841 tgcgggcagc ggcgcacgaa gtcgtcccag cgcggggcgt cctcgccctt gagcaggttt
     3901 acgacgatcg gcaatcggtc catggcgcgc atccggatcc agtcgggttc aggcggcgtc
     3961 gcggaagact tcgtcggcgc gcccccagga gaaatcggag agaagccggt cgagccgggc
     4021 ttcggtgtgc tggaggttaa tgtagtgcct gaaccgggtc tttgccgtgg cagccgtcac
     4081 gcgcggctgc tcgggatcga tttcccaggg gtggaagtag aagatcgcgg gacgacgatc
     4141 ggcggcgttg acgcgcgcga tctgccagcg cgacagcgca tagggcagca ggcggaagaa
     4201 gccgccgccg cccgcgggcc agttgcgccc gagcatgtgc acggtgctga tcggcacctc
     4261 gaccaggccg ttgggcagcc gccacggaaa gcgtggcgca tcggggatgc cgtagtggtc
     4321 gtggcggacg ggatagacgc tggagctgta gcggtagccg acatcggcaa tgcagtcgtg
     4381 cgcccaaagg ttggcctcgc cgatcgagaa gctcggcgcg cggtagccgg tgacggcgtt
     4441 gccggtgatg tcctcgagga tgaccttggc gagacggatg tcggcggtga aggcctgggg
     4501 cgtcaggtcg ctggcgcgct ggtgggcgta accgtgactc gcgacctcgt ggccggcggc
     4561 ggcgatccgg cgcaccaggc cggggtagcg ctcggcgagc cagcccaggg tgaagaaggt
     4621 gccgcgcgcg ccgtggccgt cgagcagcgc gaggatgcga tcgacgttgc gctcgacgcg
     4681 gcagggcacg ctgtcccact gctcgcgcgg aaaatgcggg gccagcgcgg agacctggaa
     4741 gtagtcctcg acgtcgcagg tgaaggcatt gatgatgctc gcagccattt cagccccctg
     4801 gcgcggcgcg gaccgcctcg tgttcgacga gccagtcgtg caggtgggcg gcgatacgct
     4861 cggcgcagcg cccgtcccag tactcgggga cccgcccggc cttgccgccg gtggcgagga
     4921 tctcgcgcgc cgcagcgacg atggcctcgg ggtggacgcc gaccagggtg ttggtgccct
     4981 gctccacggt gatcgggcgc tcggtgttct cacggatggt cacgcaggcc acgccgagcg
     5041 cggtggtctc ttcctggatc ccaccggagt cggtcagcac catgcgcgcg cccgacatca
     5101 ggccgagcat ctcgaggtag ccctgcggcg gcaggagcag gaagccgggg cctgcgaggc
     5161 gatcgagcat cccgaagcgt tcgaggttgt tgcgcgtgcg cgggtgcagc gcgacgacca
     5221 gcggcagcgc ctcgctcacc gtgcgcagcg cgtcgatgat ggggccgagg gtgtcggcgc
     5281 tgtcgacatt ggacggccgg tgcaaggtga ccacgccgta gccgccggca atgcggctgg
     5341 cgtccagacc ggcggcggcg agcagcacgt cggccgggac cgcgcgcggc aggctcgcgc
     5401 gcaggctgtc gatcatgacg ttgccgacga agaccgcgcg ctcggcaggg atgccctcgc
     5461 ggacgaggtt gtcatgggcg gagcgctcgg tagtgtagag gacgtcggag atctggtcgg
     5521 tgaggatgcg gttgatctcc tcgggcatgc ggcggtcgtt gctgcgcagg ccggactcca
     5581 catggaccac cggaatgtgg cgcttgctcg ccaccagcgc acaggcgagc gtcgagttga
     5641 cgtcgcccac caccagcacc gcgcgcgcgc catgctcgtc gatgaccggc tcgaagcgct
     5701 tcatcacctc ggcggtctgt accgcgtgcg agcccgagcc gaccgccagg ttgacatcgg
     5761 gctcgggcag gtcgaggtcg gcgaacaggc ggtccttcat tgccgggtcg tagtgctggc
     5821 cggtgtgcac cagcagcgtg cggatcggcg gattatgcgc ggcgaaggcg cggatgatcg
     5881 gcgcgacctt catgtagttg gggcgtgcgc cgacgatgca gatgaccggt gcgaaggtgg
     5941 aggcgttggt gttcatcggg tttcctcttc gggtgcggcg tcgcggcgca ccgcctgcag
     6001 caattggttg agcacggcga gcgtggccga caccgactgc tccagcccgg ccaggcgcgc
     6061 ctcgatgcgc tgcagatcgt agttgccagc catgccggcg acctggttgg cgagctcggg
     6121 cgagacacgc aggcgttcga ccgccagcgc ctcgaccggc ggcagcgccg caacgggctc
     6181 tgcccctgcc agcaccgcgc gccccatgcc cggggccgga cgtgcgcgcg gcggggcgaa
     6241 ctcttccttg agctcggcga tcacctcgcg cacctgcgcc tcggtgacca cgtgactctc
     6301 gcccagatag gcggcgagca ggaggcggtc gcacaaggtg ttgatggtgc gcgggatgcc
     6361 accggtgtgg ccatagatcg cgttgaagga gcctggctcg aagcgcgggt cctcgttcca
     6421 gccgacgtgg cgcaggcggt gctcgatgta gccccgcgtc tcctgcaggt cgagcgggcc
     6481 gaggtggtag gaagcgatca cacgctggcg cagttgctgc atctcggcgc gctgcatcac
     6541 ctcgcggaac tcgggctggc caacgaggaa actctgcagc agggcgtggt cctcgagctg
     6601 gaagttcgac agcatgcgca gctcctcgac cgcggctgca gagaggttct gcgcctcgtc
     6661 gatgatcagc agcgcgcgct tgccagcggc cgcgagcgag accaggtagg tctcgatcgc
     6721 gagcagcagg ccggccttgt cgaggttgcg gctgggcacg ccgaaggcgc cggcgaccat
     6781 gcgcaacatg tcggaggcgt cgatctgggt gctgacgatg gtggcggcga cgaccttggc
     6841 cggatcgagc tgctcgagca ggctgcgcac gatggtggtc ttgcccgcgc ccacctcgcc
     6901 ggtgatgacg atgaagccct cgctctggtg caggccgtat tcgagatagg ccatcgcgcg
     6961 gcgatggccg cggctgccgt agaagaaggc gggatcgggg ttgagctgga agggctttcc
     7021 gctcagcttg aaaaaggttt cgtacatcgg agatccgctt agaaccgcat gcccagggtg
     7081 gccgtgacgg cgttctcggt ataggcgtcg ctaccatcgg cgcgcgtatg gcggtacgtc
     7141 aggccgccgt cggtgttggc gccaagccga cggctaaccc ccagccgcgc gatggagcgc
     7201 gtcgtctcgt cgttcgccga gcctgaaccg gtggacttgc tgtgcacgta gccggcgttg
     7261 agcgtcgtga acccggacag gcgatggctg aaggaaagtg aagccgagcg cgtgctgaca
     7321 cggtcgtagt tttccagctc gcccccgaag cgaaagcccg acagggtatc gaggctgttg
     7381 cgatcgctac gctgcacgct cagcgtcagc gtgttgcgga cgccgtcgat cgtccagctc
     7441 gcccccaccg agcgctgcac gtaataggcg ttcgagcgca ccgcgtcgcg cgagccattg
     7501 cggtaggcct cgagggcgag ccggctgcgc tcgagctcgc tcaggtcggg acgcagggag
     7561 gtcagggcnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnncg cgcgcgacct
     7681 cctgctcgac atcgcgcgtg gcacgctcgt cgtagcgggt ctccgagcgc gaatagtcga
     7741 gcccccagcc gaacagacgc agcgcagccg gatcggaaag gccgacgcca agggtccggc
     7801 tctgctggtc acccaggccg ctgctgcccg cgctgccgcc accgctgcct tcgctgctgc
     7861 tgccgctgtc gagccaacgc tcacggtagc tcacctgccc ctgccctgcc gcaccgaagg
     7921 ggaagacaaa gcgcggcgcc acagagaaca cgcgcacctc gttgtcctcg tcgtagtcga
     7981 gcgcatcacc cggcaggcgg ccgcggaagg aggactggtt gtcgcgcgaa atcgaaccgt
     8041 cgacgtcgac gaagacggag ttctcgatcg cctcgaagct gccacgaccg ttcagcgcga
     8101 ggtaggtggt gttctcttcc gtgcgctcga cgtggttcag gctgcgcagg cgaaggtcga
     8161 gcccgcccct gagccgtccc gactcgcgca ccatggagac gcccggcgac acctcgagga
     8221 cccagtcctg ctggggatcg gcatccgcca catcgacgtt gtcggtccac gtgagctggg
     8281 cgttcaacgt gggctggatg cggaaggtct gtgcctgcgc cgtcccgccc acggccagcg
     8341 cgaagagcag cgcgaggggg tgcagcagcc gtggctgcgc aggttcaggc cgcattctcg
     8401 ctcggggtct cgccatagcc gtatccgtat ccatagccgt agtacgagcc cggcccgctg
     8461 cgccgcgact tgttgagcac gttcatcttc accgggcagc tctcgatcgt cgccagcgcc
     8521 tgccggatcg acgcatgcgt ggtgcgctcg gcctcgacca ccaccaccac ctgccccatg
     8581 tgggtcgcca gcacgcgcga ctcggtggtc agcagcaggg gcggcgaatc gaacacgatg
     8641 atccggtccg aataacgcgt ggccatctgc ttgagcaggc ggttcatgtt ctcggaagcg
     8701 agcagttcgg tggcgcgcga gtgcggcatg ccggccggca gcagggacag cttctcgatg
     8761 ttggtgcgca gcagcacgtc gctgagatcg tccacctcgc ccgagaggat gtccatcaga
     8821 ccgcgctcgg gcgcgagtcc gagctggcgg aacaccgatg gccgcgacac gtccgcgtcg
     8881 accagcagca cggtgtagtc gagctccatc gccatgctga tcgcgaggtt gatggcgttg
     8941 aaggtcttgc cctcgcccga caaggcgctg gtgatcatga tgaggttcgc gttgtcgatg
     9001 cgcgccggac cttcctcgtt cacgttgcgc agcagcggac gcttgatgac gcggaactcc
     9061 tcggcgatcg tcgagcgcgg ccggtcgggc gtgaccaggc ccttctcatg gagcatcgcg
     9121 aggtcgatcg tcacgctgcg cgagaccggc gcggcgcgaa cctgcggctg taccagcggc
     9181 ggcgcggacg aacgcgcgac cggcgtgctc gcgccctcct cgtcggtcag cgcctccacg
     9241 ggagcggcga ccgggacagg ctgcagctcc gcgggctcgt ctcccggctc ggcggtcgcc
     9301 tgcttgagct ggtccaggcg ctgtgcggct ttttcgataa ggctcatgat ggattccggt
     9361 tcaaccctgg atcagttgca aggccacgac cgccgcggcg accatgccga cataggcgaa
     9421 cagtcctgcc ccgaaggcga gcagcccgcg ccgacgcgcc gacctgcgct cgggtgtggt
     9481 cagcatcgag accgtaccga gcacgggcag cccggtcacc tcgcgcaggc cgcgcggatc
     9541 gaccaccgcg ggcctcaact ggctgatcag gaaggtgagc gcaaagccgg cgatcagccc
     9601 gatcaggccg gccaccggaa tcagcagcag gcggtttggt gcggacggct tggtcgccag
     9661 cgtgggagga tcgatcacgc ggaaatcggc gacgccggtc tgcgtgttca tctccacggc
     9721 gatgttggcc gactcgcggc gcgccaccag cgcgtcgtag ttggtcttgt gcaccgcgta
     9781 gtcgcggttg agctgggcaa gctcggcttc cacctcgggc accagccggg cacgctcgcg
     9841 cagctggtcg aggcgggact ggaattcggc cacgcgcgca ttcagggacg ccacccgcga
     9901 ttcggcctgg gcgagcgcga gcttcatctg ctggaagtag gggttggcat cgagcgcgcc
     9961 gaactgcgaa ccgccggcgg cctgcatggc ctcgacctgc gtccgcttct gcgcctccag
    10021 ttcctcgatc aggcggcgcg tgccggtgac gtcgggatgc ttgtcggtgt agcgcagcag
    10081 cagctcgtcg aggctgcggc gcagcacgtc gatacggccg tcgatctcgg gcaccgacac
    10141 cgccgactgc gaaggcgcct ggggcagcag caccggctcc tcgccgacga gctggcgctg
    10201 cagcgcatcg cgtccattca tcgcctcgcg ctgctcgagc tgggcctgct gcagctgggc
    10261 ggtcatcgcg ccgatctggg aaatgtaatc ctgtgcgccg tcgccgagca cgcccatgtt
    10321 gcgcaggcgg aactccttca cgcggttctc cgcctcggtc agcttctgct cgtacgtctg
    10381 gatctgctcc tcgatgaagc gacgcgccgc gtcggcgtcc tggcgctttc cgcccagtcc
    10441 ggattcgacg aacagcgaca gcagcgactg cacgacgcgc tgcgcacgct ccggccgggt
    10501 gtcggcgtac gagagcatga agaggttgtt acggtccgag gagccgatgc gcagatccct
    10561 cgacagccgc gtgatcagcg cctcacgctc ttccgtcgta ttcacgccga ggtcgagatc
    10621 ggccatgttg atcagcttct cgacgttggg ccggctgatc agggttcggc tgagcatcgt
    10681 gatctgctga tcgatgttgg gctgtacagc caggcccgcc atcagcgggc gcagcaccga
    10741 ctgcgtgtct acgtagaccc gtgcactcga ctcgtatttg tcgggcatct ggtagatcac
    10801 gagaccggcg accaccccca caatccaggc aagcgccatc ccccaccagc ggtagcgcca
    10861 catgccgcgc aggtagctgg tgatctgcgt tacgagttct tccatcgatc ggcttcaagt
    10921 ggttcgaggc cccctcgtcg gccacgcgac cgagggagtc cccgaggttg aatcaacccg
    10981 cgccagcggc cggagtcaga accagctctg cggaatgatc aggacgtcgc ccgggcgcat
    11041 ctcgacgttg gccgagacgt ccccgcgctt gatcaggtcc ttgatccgca cgctgtactg
    11101 cttgttgccc tcgcccgtgc gcaggatcgt ggccgagttg ccgtcggcga actcggtcag
    11161 tccaccgacc gcgatcatca cgtcgagcag ggtcatcttc tggttgtagg gaaggatgcg
    11221 cggctccgag gcctcgccca cgacccggat ctgctcgctg tacggcccgg agaagctggt
    11281 ggcgatgacg gtcaccacgg gttcgcggat gaacttggcg agttcctttt cgatgtcacg
    11341 ggccagcgtg ctggtgtcct tgccctgcgc gaccagatcc tccacgaggg gagtggtgat
    11401 cttgccgtcc ggacggatcg gaacgctcat cgacaactcg ggattgcgcc acacgacgat
    11461 attgaccgag tcgccagcgc cgagcacgta gctgtattcc gcgtccgcag cgaggggagg
    11521 cgcaggaggg aaggaagacg cacaaccgac gagcgaactc gccacgacga caccaagcag
    11581 gcaacgggca gcgcggaagc gcgcaccgga cacgcaactg aacatgaaaa cccccctctg
    11641 aattcgctga gacgcaaatg atacgatgac cgccacggtt cgatgatgct acgggttcga
    11701 ttacagcatg aggaggaacc agtgcacaca agcgcgcaca tcgctggggc gtgcgaaaaa
    11761 ccggattcac tcctcgcgga ttccggttta ttatctaact tcgaatgatt gtgttcgcgg
    11821 cctctcgacg gctccgcggc gcagaaaacg caaacgaacc gggccacttc aatgcgtcat
    11881 acaactgccg tgcggggcga tcacgcccgc ttcccgacgt cgaagctcgt ctacttcccg
    11941 acgaccggcc gggacgcgat taacgagtca tccccgctac tcgatccgga cctgccggat
    12001 ctctccgccc tgcttcagga cctgtctttc gagcgcaacg gatacgagat ccgggttgcg
    12061 agcggctccg actgcctcaa gcgccgggcc gccaagctca tcgagcgcat gtactcttca
    12121 cgcggcctgt tcccctacgg cacgatggcg gaaatcgaca agcgtgacgt caccgtcgtg
    12181 gccctgtgcg gcgatgacgc cgttgccacg ctgaccgtgc gaatggattt cggcaacggc
    12241 ttgttagcgg acactttgta cagcaaggag atcgactccg cccgcgcgat cggaggcaaa
    12301 gtgtgcgaaa ttacacaact ggcgctcgat ccctcctccg gcaaccatga tgccttggcg
    12361 ggcctgttcc aggcgctgta cgtgatcgca caactcacgc ggcgcatgac cgacatcttc
    12421 atcgaggtgc acccacggca tgcgaacttc taccagcgca tcttcgggtt caaacggatc
    12481 ggcggcgagc gcatctgccc tcgtgtcggc gcgccggccg tgctgctcca cctgtcgcag
    12541 gacgaattcg agcgcgcgct cgcccgtcac gaacgcatcg agcaacggca caacagccgc
    12601 gtatcccgcc tgctgccgat gaaggcccac gcgcaggaag tgatcgaggc gctctccagc
    12661 cgctaggccg cggcgctctc gagctgcggc gtcagaacca gcggcgcaat tccagccacg
    12721 cacgatcccg gtcgtcgtaa accccgaaca tccccctgcc cttgccgccg aacacgtcca
    12781 cgcccacggt cgcgcgccag gcgggagcga acttccagct aagcttcggg cgcagcgagt
    12841 agtcggatcg attcaggctg gtcaccgcga gcacctctgc ctcgagatcc gttccggtgc
    12901 cgtgcacgat ctgcaggctc acgccctgct cgtggcgatc catcatcatg gctggccgat
    12961 ggtcgtccag gcggcgaccg tagtactgca cgttgaagcg ccagtctccg ctcggcagat
    13021 cgacgccgaa cgcgtaatcc accatgtcgg tgccgaccag gccgaccacg ggcagatttc
    13081 ccgcccgcgc aaaggtattc acgctgcgac cactcgtgtg aaccgcctcc cccttcagca
    13141 cgaagctgcc gagatccttg ctgaaggtgc cgccgacctg gtcgatgcgc tcgtggcgca
    13201 gctcggcccg gccgggcgcg taggcatgca gcgtcggcgc gacgtcgtag ctgtgatagt
    13261 agaaggccga aagatcccac ccatcgacca gatgcgagat gcgcgcaccc cagttgccgt
    13321 cgtcgatgtc gccgccgggc cgatcctccg acaccacggt gtcggccggc atccacggat
    13381 aggtgtagaa gtcgctgccc ggcttgccga tctggtcgaa gctgggcttc ggcacccaca
    13441 gcagttcgaa gtgggtgtcg gcgccgaagc gttcggcgcg aaccgcccac tgcccgatgc
    13501 gcatgcgctc gagctcggtc tgcaggaagt cacgcatatc gcgcgcggac accacgtcgg
    13561 cgaagaagaa gcccaccatc tcgccccaca ccacgtgctg gcgaccgaag cggaactccc
    13621 agtcgccatg gccgacatcc acgtacgcct cgcgcagcat gaggtcgcga cgctggtcgc
    13681 ggcgcaccgc agccgggtag tgctcgtcct cgagatcgaa ggcgccgtcg agttcggcac
    13741 gcgcgttgag cttccagcgc acccgcggcg cgacttgccc gctgcctgtc agctccccgc
    13801 gggcgcgcag gtgcgaccag cgctcgggat cgcggtaggt gtacgccatg ccgagctcgg
    13861 cgtagccgcc ccacttgatg cccgtcgccg cctcgctgcc cgctgcaggc gtgccgacgt
    13921 cgagcagggc gtcgagatcg gcgtccgacg ccgcgtcgag atcggcgtcc gctgcagggg
    13981 catcgtcggg caggtcggca gccgcagctt cgtccgcgag cgcagcctca ggcacatccg
    14041 gcgccgcgtc cgcggccacg ggctccgcgc gcgcggnnnn nnnnnnnnnn nnnnnnnnnn
    14101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14161 nnnnnnnnnn nnnnnngcag cctcaggcac atccggcgcc gcgtccgcgg ccacgggctc
    14221 cgcgcgcgcg gcaggtgtgg cgaggcttgc gagcgcaagc gcgatcaggg tcaggcgatg
    14281 gattctgttc aggcggggca tgtgcagtct tcctagattt cgcgaatgtc ttcgtcgcgc
    14341 ggcgtccgcc catcgacgaa cacccagcgg tcgtcgaccc tcaagccgag cgcggtgatc
    14401 tggccatccg cgatgcggac caggcggtcg gccatgttca tgaccttgcg gtcgtgggtg
    14461 gaaaagacga aagtcgtccc cgactggcgg ttgatgtcgc gcatcagctt gaggatgctg
    14521 gtgccggtct tgctgtcgag gttggcggtc ggctcgtcgg cgaggacgac cttggagtgc
    14581 gtggccagcg cgcgcgcgat cgccacgcgc tggcgctggc cgccggagag ctgattgggc
    14641 cgatgctcgg cgtacttctt cagaccgacc acgccgaggt agtggcgcac ccgctcggca
    14701 cgctccgccc tggtgagctc cggcatctgc agcagcggat actcgacgtt ctccgctgcc
    14761 gacagcacgg ggagtagatt aaaggtctgg aagatgaagc cgatggtacg tgcacgcagg
    14821 tcggccagct cgtcgggcgt gcggttcgag acgtcatgcc cgtccacgac cacacgcccc
    14881 gaggtcggcg tgtcgatgca gccgatgatg ttcagcaggg tcgacttgcc actgcccgaa
    14941 ggccccgcga tcgccaggaa cactcccggc tcgatctcga gcgagacgtc gtcgagcgcc
    15001 agcaccgtct gctcgccgag gcgaaaactc ttgctcacgt gttcgatctg gacgatggcc
    15061 atcgggacga ccgaaaatga agaaaacccc cagaggatag cacccatgac gccaagctta
    15121 cgatcccgcc gccgattcgt cgcctgcctc gccggcagcc tgatgctgcc cacgctggcg
    15181 cttgcgaccg acgccgcctc ccctgccgag cccgcagggg ccgagggcgt cgacacggtc
    15241 gcggccgacc tggtccggcg cgccgacgcg atccgctttc cgcgcgagag cttccagacc
    15301 gagatcgtcg tgcgcaactt cgccgatggc gcggagggcg agtcgcgcac cttccgcgtg
    15361 ctctcgcgcg gcaacgagaa caccatcgtg ctgacgctcg agcccgcaac cgagcgcggc
    15421 caggccctgc tgatgcgcgc gcgcgacctg tgggtcttca tgccgagcgt gtcgcagccg
    15481 gtccgactgt ccctcgccca gcgactgacc ggtcaggtgg ccaacggcga tctggcgcga
    15541 gcgaatctgg ccggcgacta catcccgacc gtcgccggca ccgagaccat cgagggccag
    15601 gccgcggtgg tgctggacct caaggcggtc gatcgcggcg tgacctatgc gcgcgtgcgc
    15661 tactgggtcg gcgagcgcga cagccgtccg ctcaaggccg agttctacgc gctctccggc
    15721 cgcctgctca agaccgcgcg ctacgaggag ttccgccaga tggccggcgc agtccgcccc
    15781 acccggctgg tcatggagga cgcgctcaag aagggtgaga tctcggtgct gacctacgag
    15841 aacatgaacg ttcgcgacct ccccgagcgc atgttcaccc gcgagtacct gcgccggctg
    15901 cagcagtagc cccggtgccg aacgcgcacg tcctcagacc acgatgcgca tgcgctcgcc
    15961 gaccaccccc tggaggtggc cggcgaaggc cgcgcgcacc gcgtcctcgc catgcaccag
    16021 gcggacctcg ccgggcagat ggcgcatgcg ggtgacgaag cgggtcaggt cgtcgcggtc
    16081 ggcgtgcgcc gaatagcccg aaaggatatg gatgccggcg cggatgtcca cacgctcgcc
    16141 gtcgagctcc acgtagccac cgcgcggccc gtaggtctga atcgcatggc caggcgtgcc
    16201 gcgcgcctgg taaccgacga agagcacgtc gtggcgcgga tcacccagca tctcgcgcaa
    16261 gtaattcacc acccggccac cggcgcacat cccgctcgcg gcgatcacca ccgcgggctc
    16321 gcggctgcgc gcgagccgac gcacgttggc gagatgctcc tcgtggctgt cgatcgccac
    16381 gagctgatcg taggacagtg gctgccggcc ggcacgcacg cgggcgcgcg cctcggcgtc
    16441 ccagaacggc tgcaactcgc gatagagcgc ggtgaagcgc tgcgccagcg gcgaatccag
    16501 gaagatgcgc aacgcgcccc aggcggcgga atgcttcccc gggcgcaccc gctggcggtg
    16561 caggatgtcc tcgaactcgt agagcagctc ctgcgtgcgc ccgatgctga aggcgggcac
    16621 gatcacggtg ccgccgtcct gcaaggcgtg ctcaacgacc gcctgcaggc gtgcgcggcg
    16681 gtcgcggcga ttctcgtgga cgcggtcgcc gtaggtggtc tccagcacca gcacgtcggc
    16741 cctccagggc gggcgcggcg ccggcagcag cggcgcatgc ggcgcgccga gatcacccga
    16801 gaacaccacc cggcgcggct ccggccatgc cgcaccggag agctcgcact cgacgtaggc
    16861 cgagccgagg atgtggccgg cgcgctgcag gcggatccgg caactcgcgt ccgggctgcg
    16921 atacacgagg tgccacttgc cgtagggcag cgcgcggatg cgcggctcca ccttgcccag
    16981 atagcgctcg atcagcgctc ggtcgcgact cacacccacc gcgaaggcgt ccgcgagcac
    17041 cgtgggcagc aggcgcgcgg agggttcgct gcacaggatc ggccccttga agccggcggc
    17101 gagcagccag ggcaggcggc cgcagtggtc gatgtgcaca tgggtgagca ccagcgcgcc
    17161 gacgccctcg agcgggaagt cgatctccag ccggtcggcg gccgagcgcc cgtcgggcgc
    17221 ggtctccgcg ccctggaaca ggccgcagtc gagcagcagg ctgttgcgcc cctcgacgaa
    17281 gagctggtgg caggagccgg tgacgccgtt gcgcgcacca tggtggagga tcgtcgggtt
    17341 catgacgtca ttctagacgc ccattcgcca gcgtccaccc gcaaccctgc cccttcaacc
    17401 gctgcgcccc gcaagcgcgc tggcaagcac gaaggctggg atgacgtccg cgcccgtcgt
    17461 atgggagcgc cggcaggcgc gaacgcggcg gttcggcacg cgccacaccc aacgtagccg
    17521 cgcaaacggc cgcccgattc gcgcctgccg gcgctcctac ataaaccgtc gtgcgaaatg
    17581 gtgccgtgct tcgccgcgcg cggcgcctgt gcatgaacca tcgtgcgggt tggcggccga
    17641 cgtctcgcgc gcgacaccgc cctgtaggag cgccggcagg cgcgaatgcg gcggtaacgc
    17701 acgcgctccc gctgcaggag caccccgcaa gacgcccccc ctactccatc ccccacttct
    17761 gcagccggta gcgcagctgg cgcaaggtca tgccgagcat gcgcgcggcc gccgagcggt
    17821 tccagcgcgt ctgctcgagt gcacggatga tgcgcaggcg ctccacctcg tcctggccct
    17881 cgcggccttc ctcgggttct gccactggcg cggtgccccc ctcgacccca gccgtggccc
    17941 cgagcgggct gcagtcaccc tcgaccccga ggtcgccgac gtcgatttcc tcgccctcgc
    18001 acagcgcaca ggcgcgctcg agcaggttct ccagctcgcg cacgttgccg gggaaatcgt
    18061 aggcttgcag gcgctcgagc gccgccgtgg agagtcggcg cggcgccccg ccctcgcgca
    18121 ctgcgaggcg cgcgaggatg tggctggcca gatccgggat gtcctcccgc cgctcgcgca
    18181 gcggtggcac gcgcagcgtg atcacgttga tgcggaagaa caggtcctgg cggaagcggc
    18241 cctcggccac gaggcggccg agatcctgat gcgaggcgga caggatgcgc acgtccaccg
    18301 gctcctcggc gtgcgcaccc accgggcgca cggcacgctc ctggatcgcg cgcagcagct
    18361 tgacctgcat cgccagcggc agctcgccga tctcgtcgag gaacagggtg ccgccgctgg
    18421 cggcctggaa cagcccgctc ttgtccgcgc tcgcgccggt gaagctgccc ttgcggtggc
    18481 cgaagaactc gctctccatc agctcgggcg agatcgcccc gcagttgacc gggacgaagg
    18541 gcccgccggc gcgcgcaccg agcgcgtgga tgtggcgcgc gatgacctcc ttacccgtcc
    18601 ccgattcgcc atggatgaac accggcgcct ggttgcgcgc gagcttctcg gcctgcgcgc
    18661 gcannnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnccatgga tgaacaccgg
    18781 cgcctggttg cgcgcgagct tctcggcctg cgcgcgcagc tgcacgaagg ccgccgagtg
    18841 gccgatcagg ctgcgctcgg cggtcgcggc ggggtgctcc tccgagcccc cctcgcgcag
    18901 cttgagcgcg tgctgtacca gctcgcgcaa ggccttgagc tcgaccggct tggtgacgaa
    18961 atcgaaggca cccagcttga gcgcacggat cgccgtctcg atgctgccga atgcggtgat
    19021 caccgccacc ggcaggccag ggcgcacggt ctggatgtac tcgaccagct ccagcccgtc
    19081 gccgtcgggc aggcgcatgt cggtcaggca caggcgatag ccgcgctcgg ccagcagcgc
    19141 gcgcgcctcg ccgaccgagc ccgcggtgtc acaggccagc cccatgcgca tcagcgagag
    19201 ctcgagcagt tcacggatgt cgtcctcgtc atcgacgacg aggacatcgg tggagcgggg
    19261 ccggttgcgg cgttcgacct gggtcatggc tgctggctcg cggtaaggat gaagtcggcc
    19321 ccgggaccgc ccggcgcgag cgccagagtg gcgtcattgg cttcggccag ctcgcgggcg
    19381 atgtacaggc cgagcccggt gcccttgggg tgggtggtga agaagggttc gaacagatgc
    19441 gcccgcatcg cctcgtcgaa gcctgggccg tcatcctgca cgtgcagcac gaccttggcg
    19501 tgcggcaggg gctctgccca caggcgtacc gcgcccgcct tgcccgaggc gtggcgggcc
    19561 gcattcgaca gcaggttgtc gaggatctgg tgcaggtgag cgcgatccat cgccagggtc
    19621 agcgcgggat cgatcgcgag ctcgtacagc tgcgcctcgg cgggctcgcg gaacacccgc
    19681 gcgtcgagga tctcgcgcac aaaggccgcc agcggcaggg cctcgggcaa ggcctgctcg
    19741 cgcctgccga gggcgagcac gtcgcggatc atgcgctcga tgcggcgcgc gttgtcgttg
    19801 atgatgcgca ccagccgggc ctgcatgtcg gcgcgcttct cctcgccgag cagctcggcg
    19861 gcctgggtca ccgccgacag cgggttgcgg atctcgtgcg ccatgctggc ggtgaggcgg
    19921 ccgagcgcgg cgagcttgat ctgctgcaac tggcgctgga tctcctcgta gtcggtgaga
    19981 tacagcaggg tgtcgccttc ggccgcgctg cccgcatcgc cctgcacccg gcggcaacgc
    20041 agcaggcgtc cggccgcgcc cagccgcatc aggcgcccct cctcgcccac cgccggctgc
    20101 agcatgccct ccagcccggc gtcgaggtcg gcgagcgcga ggccgtcgag cgcctccccg
    20161 ccagcacggg ccaggccgag catttccagc gcctgggcgt tggcgtggag gacgcggccg
    20221 cgcgcgccga ccacgatcac gccgtcctgc atgtcgcgca ggatatgggc gctcaccgcc
    20281 tgctgcttgg cgagcgccac gccgcgctcg gccgccagcg cagcgttggc ctgagcgcgc
    20341 agggcgagca ggcgtgcaat tgcggcaatg ccgaagaagc cggcgcagaa gatgccgacc
    20401 tggaggaact cgaccgactt gccgcccccg aagagacgcg aggcgttctc cgccagcacg
    20461 gccagggtgg cgagcgcagc cgagaacatc accatgcgcc cctcgccgat caggccggcg
    20521 ccggcgagca tcaccatcat cagcaccggc atgccgctac ggtagccgcc gctcacccac
    20581 atgatcgccg caagcgcgac gatgtcggca agcgcgagca ggatcaccac gcgctcgaag
    20641 cccagccgcc gcaccgcgtc ggggaagccg agggtcagca ccgcggtgag gtagcccacc
    20701 accgcggcga ggtagaggcg cgggctctcg ctgccgaggc cgaactcctc gccggcgacg
    20761 aggaacaggc cgccgaggat cagccggaag acgttgaggt aacgcagggc gcgctggcgt
    20821 gcgcggtcgg ccgaatcgac cgcgaaggcg gccgcctcaa tcgggtcgtg ggccggcacg
    20881 gcgatgttcg tcgcagcaat agaaggactc tccagcgcgc acgccctcgg actcgggcac
    20941 gatcagcccg cagtggcgac actcgcgcat cggctcggac ttcgccaggc gcgcgtcctc
    21001 ggccttgcgc ccgaggccgc cacgcgcctt gaggcgacgc accgccgcgc gcgcccacca
    21061 gatgccgaag acgacgagga tcagcaggag caggttgcgc acgttggggc cggaggaaag
    21121 tcgggaacgc caaaattcta gcatgcgccc ccgccgcccc ccctgcaggc gcccccccgg
    21181 cgatgcccgc gcgcctaccg cgcgcccggc cggtttgcga caatgtcgga ccgcaccgca
    21241 ccgagccctc gccgccatgc cgcacttccc cgcgccgatc gaatcccgcc tgccgaacgt
    21301 cggcacgacg atctttaccg tgatgtcccg cctcgcccag gaatgcggcg cgatcaacct
    21361 gtcgcaggga ttccccgact tcaacgccga ggacctgctg ttcgagcgcg tcgcgcactg
    21421 gatgcgcgcc ggccacaacc agtacgcccc catggccggc acggcggcgc tgcgcgcggc
    21481 gatcgccgcc aaggtcgagg cgctctacgg cacggcctac gaccccgaac acgagatcac
    21541 cgtcaccgcc ggcgccaccc aggcgctgtt caccgcagtg accgcctgcg tgcacccggg
    21601 cgacgaggtc atcgtgttcg agccggtcta cgactcctac gtccccgcca tcgagctcgc
    21661 cggcggcaag gtggtgcgca tgcgcctggc cgcgcccgac taccgccccg attgggacgc
    21721 ggtggcggcc gcgatcgggc cgcgcacgcg catgatcatg atcaacaccc cgcacaaccc
    21781 caccgccacg gtgtggacac gggacgacct cgaccgcctc gccgcgctgg tgcgcggcac
    21841 cggcatcgtc gtggtggccg acgaggtcta tgagcacatc gtcttcgacg gcgccgcgca
    21901 tgcctcctgc gccgcccacc ccgcgctcgc gcagcgcagt ttcgtggtgt cgagcttcgg
    21961 caagacctac cacatcaccg gctggaaggt gggctacgtg ctcgccccgc gcgagctcat
    22021 ggccgagttc cgcaaggtgc accagttcaa cgtattcacg gtgaacaccc cggtgcagct
    22081 cgcgctcgcc gactacatgg ccgacgcctc gcgccacctc ggcctggccg ccttctacca
    22141 ggccaagcgc gacttcttcc gcgccgcgct ggccgcctcg cgcttcgagc tgctgccctc
    22201 gcacggcacc tacttccagc tcgcgcgcta tgcggcgatc tcggacctgg gcgacgccgc
    22261 cttctgcgaa cacctgaccc gcgatgtcgg cgtggcggcg atcccggtgt cggccttctt
    22321 cgccgacggc cgcgacgagc acgtgatccg cttctgcttc gccaagaacg aggccacgct
    22381 cgcggccgcc tgcgccaggc tggcggcgct ttaggccgcc cgcccaagcc tgcccgtaca
    22441 gccccacccg ccccacacca ccagagcgct ccgatgttcg aacaacccat ccccacgctg
    22501 cagcgcgacg gcggcaccgt ccgcatcctc gaccagaccc tgctgccctt ccgcaccgag
    22561 accgtcgcac tgcgcaccct cgccgaggcc gcgcacgcca tccgcagcat gcaggtgcgc
    22621 ggcgcaccgc tgatcggcgc caccgcggcc ttcggcgtgg cgctcgcgct cgccgacgag
    22681 ggcgccgacg acgccgcgct cgcgcgcgcg ctcgccaccc tgggcgccac acggcccacc
    22741 gcggtgaacc tgcactgggc gctcgagcgc atgcgccgcg cgctgcagcc cttgccgccc
    22801 ggcgcgcgcg tcgaggcggc gtgggccgag gcggaggcga tccgcaccga cgacgccgcc
    22861 acctgcgacg cgatcggccg ccacggcgtt cgcctgattc gcgagatcgc cgcccgccgc
    22921 cccggcccgg tacggctgat gacgcactgc aacgccggct ggctggccac ctgcggcgcc
    22981 ggcaccgcgc tcgcgccggt gtatgcggcg caggccgagg gcatcgcggt cgaggtcgtg
    23041 gtgagcgaga cgcggccgcg caaccagggc ctgctcaccg cctgggagct gcgcgccgcc
    23101 ggcgtgcccc acctgctgat cgccgacaac gccgccggcc tgctgctgat gcggcacgag
    23161 gtcgacctgg tcatcaccgg cgcggaccgc atcgccgcca acggcgacac cgccaacaag
    23221 gtcggcacct acctcaaggc gctcgccgcc cgcgtcgccg aggtgccctt ccacatcgcg
    23281 gcgccgcact ccacgctcga cttcgcctgc gccgacggcg ccgccatccc gatcgaggac
    23341 cgcggcgccg acgagatcct gcacgtgcgc ggcgaagccg cggacggcgc caccgccgag
    23401 ctcgcgctcg cccccgcggg cacgcgcgcc gccaaccccg cattcgacct taccccggcg
    23461 gcgctgatca ccggcatcgt caccgagcgc ggcatcgccc gcccgggcga gctcgcccgc
    23521 ctctacccgg agcaggcgcg atgagcgccg gcacgcccgg ctgcatccac gaggaggccg
    23581 gctggcgcgg cgaggacgac ccgcgcgcgc gcctgctcca caccctgcgc gcgatgggcg
    23641 cggcgcggct caacgtcggc acctcgggca acgccagcca gcgcctagcg ggcgggcgca
    23701 tgctgatcag cccgagcggg atcgccgccg agcgctgccg cgccgaggac atggtggtgg
    23761 tggaggccga cggccgctac gccggcgcgc gcgcgccctc gtcggaatgg cagctccacc
    23821 atgacgtcta cgccgccttc ccggcggccg gcgcggtgct gcacgcacat gcccccttcg
    23881 ccaccgcgct cgcctgccag cgcctcgaca tccagccctt ccactacatg atcgcgcgct
    23941 tcggcggcac caccgtgcgc tgcgcgcgct acgccacctt cggcacccag gcgctgtccg
    24001 aggccaccgt ggcggcgctg cacgagcgca gcgcctgcct gctcgccaac cacggcatgg
    24061 tcgtcttcgg ccgcgacctc gagcacgcgc tggcgatggc agtcgagttc gagaccctgt
    24121 gcgagcaata ctggcgcacc ctgcagctgg gcgcgccggt gctgctgtcg gaagcggaga
    24181 tggccgaggt gatcgaacgc ttcaagtggt acggcaagcc gcgcgcctga accgccgatc
    24241 cgaccatggg agcgcccccg cccgcgaaga ctcgccgctc gggaacctag ccctccagca
    24301 cccggagcag gctcgcggtg tcgtcccgcc cccagcccgc gcccatcagc gcgtcgagct
    24361 gctgccacac ctgcgccgcc accggcagcg gcgcgccgag gcgggcggcc tcttccatca
    24421 ggatggcgaa atccttgtgg tgcaggcggg cctcgacgcc ggcggcgaag tcgcgcgcca
    24481 ccatcttcgc ccccatcacc tccagcaccc gcgagcccgc cgacccgccg gcaagcgcac
    24541 gcagcaccgc ggccttgtcg accccgtgcg cgccggcgag gcggaaggcc tcggcgcagg
    24601 cctggatcgc cgacaccatg atcatctggt tgcaggcctt ggccacctgc cctgccccgg
    24661 gcgggccgat gtgcacgatg cgcttgccga gtgccccgag cagcgggcgc acgcgctcca
    24721 gcatgtcgtc ctcagcgccg gccatgatcg ccagcgtcgc gtcgcgcgcg ccctggccgc
    24781 cgccggagac cggcgcatcg acccagccga cgccgcgcgc ggcgtagcgt tcggcgagcg
    24841 cgcgcgccgt cgccggggcg atggtgctca tgtccacgtg gatggccccg ggcacgaaac
    24901 cctcggccag cccctgcgca ccgaaggcga gcgcctccac gtcggcgctc gcggtgacga
    24961 tggtgatcac cacctcgctg cgcgccgcca gctcggccgg tgtcgcacac agcggcacgc
    25021 cctcggccac cagcgccgcc gccgactgtg gccgcctcgc ccacaccgcg agcgcatgcc
    25081 ctgcggcgcg caggtggcgt gccatcggct cgcccatcac gcccagcccg atgaaaccga
    25141 ccctcatcgc cccgccctcc accctgcctt ccgtcgcgct catgcgccca ccccgccgct
    25201 catgcgctcc agcagcttga gcatcgccac cgaatcgtcc tcgcccatgc cgcagccgat
    25261 catgccgttg aagagctgcg ccgtggccgc ggccgcgggc agcgccacgc cgagccggtg
    25321 cgcctcgccc atgacgatgc gcaggtcctt ctggtgcatc caggccttga agccgggccg
    25381 gaagttgcgc tcgagcatgc gctgaccgtg gttctcgagg atgcgcgagt acgcgaagcc
    25441 gccgagcagc gcctcgcgca ccttggtccc atccgcgccg ctcctggccg cgaagttgag
    25501 cgcctcggcg accgccgcaa cccccacccc ggtgatgatc tggttgcagg ccttggcgac
    25561 ctgcccggca ccggcctcgc cgatgcgggt gatggacttg cccatggcct cgaaaagcgg
    25621 ctgcacgcgc gcgcaggccc cctcgtcgcc gccgaccatg atggtgagcg tgcctgcgat
    25681 cgcgcccggt tcgccgcccg acaccggcgc atcgagcgcg acgatgccgc gctcggccag
    25741 gcctgcggcg atggactgcg ccgcggcggg agcgatggtg ctcatgtcga tgtggacatg
    25801 gccggcgccc gcaccatcgg cgatgccgtc cgcaccgagc gtcacctgct cgacgtcggg
    25861 cgcgtccgac accatgctga tcgtgaccgc cgcgcgccgc gccacctcgg ccgcgctcgc
    25921 gcaatcgctg gcaccggcgt cgagcagcgg ccgcatcgat tcgcggcggc ggctccagac
    25981 gtgtacgcgg tgaccggccg caagcaggtt gagcgccatg ggacggccca tgaggccgag
    26041 tccgatgaat ccgacttcca taggctggag tcctcctgaa aaagcggggg gtaggcggct
    26101 ggctatgcgc gggcgagccc gcccgcactg cgcgggcgcg gcttcgaccg ccgcacgcgg
    26161 caaccgacgc cggcgttcgg cgcgcgacgc gtacgcaagg ccggctggtc gggcggcgcg
    26221 aagctcgcca taatcgccgc catgaaatac ggtccaatca tcaaggaaat cgggcggggc
    26281 gccaagggtg cccgcgacct cgacacggcc gccgcggcgg cgctcttcgg cgacatcctc
    26341 gatggcgtcg tgcccgagct cgagctcggc gccatcctgc tcgccttccg catcaagagc
    26401 gaggcgctgc ccgagctgct cggcttcaag caggcgatgg atgcacgcac cgcgcaggtc
    26461 gccgtgccgg acggcccgcg ctgcgtggtg ctgccgacct acaacggcgc gcgccgccag
    26521 gccaacctga tgccgctggt ggcgctgctg ctcgcgcgcg agggcgtacc ggtgctgatc
    26581 cagggccgcc acgacttcga gacgcgggtg agccccttcg agctgctcgc cgcgctcgag
    26641 ctgcatccgg ccaccgacgc ggccgaggcc tcggcgcagc tcgcgcagcg gcgcgtcgcc
    26701 tgcatcggcg tggacaagct gctgcccggg ctcgacccgc tgctcgcgct gcgcgtgcgc
    26761 atgggcgtgc gcgccagcgg ccataccatg gccaagctga tcgacccctg ccgcgggcgc
    26821 agcgtgcgcg tggtggcggt gacccacccc gagtacctcg agcgcatgga cgccttcctg
    26881 cgcgccgacg gcgggcgcgc gatgctcatg cgcggcaccg agggcgagat ctacgccaat
    26941 ccgcggcgct gcccggagat gaaggtgtat gtggagggcg aggcgagcgt gggcgtcccc
    27001 gccgaggaag gtggcgcgcc gccgctcgcc gggctgcccg acgcgccctc ggtggcggac
    27061 aacgccgcgc tgatccggtc gatgctggcg ggcgaggtcc cggtgccggg gccgatcctc
    27121 cggcaggtgg ccgcgctgcg ggcgctggcg aactgaaacg ccccgtctgg aagcgggccg
    27181 gcccgcgaac cggccatcga ggacgcgttc tttggcgggc aagtccgctc ccaccgcaga
    27241 acctgcgcga aacgccctct cgcatcccct ttcgcgggca ggcccgctgc cacggcagtc
    27301 cggggcacga gacggcctcg tgcctgccga gcacgcgctg cgctcaggcc gcgagccggc
    27361 cggcgcggta gtcggccacc gcctggtaga tctcctgctc ggtgttcatg acgaaggggc
    27421 cgtactgcgc gatcggctcg ccgagcgggc ggccggcgat cagcagcacg cgggcctcct
    27481 ccaaagcctc gatgcgcacg ccgtcgcggt ccgcggcgtt ggcgaggatc gccatgttgc
    27541 gcaccgggac ctccacctcg ccgagcttca cccgaccgcg atacacatag acgaaggcgt
    27601 tgtgcccggc gggcagcggc tgcgaaaagc tcgtgccgca gggcaggtgc aggtcaaggt
    27661 agagcggcgc ggtgaccgcg cgcgtcacgg cgccgcgcac gccgtggctc tcgccggcga
    27721 tcacggtggc ctcgacgcca tcttccgtgg tgaagcgcgg cagctcgccc gcggcgaagt
    27781 cgcgatacca gggcgcgctc atcttgtctt gcgcgggcag gttgagccag agctggaagc
    27841 cctccatgac gccctcctcc tgctgcggga tctcggagtg gatgacgccg cggccggcgg
    27901 tcatccactg cacgccgccg ttctcgagca ggccctcgtg gccggcgctg tcgcggtgca
    27961 gcatgcgccc ggcgatcatg taggtcacgg tctcgaagcc gcggtgggga tggtcgggga
    28021 agccggcgat gtagtcgtcg gcctggtcgc tgccgaaggc gtcgagcatc aggaaggggt
    28081 cgagccggcg ctgcagcggc tgggtgagca cgcgcgtgag cttgacgccg gcgccgtccg
    28141 aggtcggatg gccggtcacg agccgctcca ccgtgcgcgg atggtgcacg gccgcggagg
    28201 gggtgcgggg ggcgggggtc gtgctcattt gcgtgctcct ctgtatgggg tcgggggtgt
    28261 ggggcgggtg ggcccgccct cgttgtccag gtcggcctcg cgccgccgcc ggcggtcacg
    28321 aggcttgccg cgcatggctc aggcgagcgc ggcggcgatg tccgcctcgg cctcggcgaa
    28381 gccctgcttc gtagcctcct cacccatgtt cagcccttcg gcatagatga aatgcacgtc
    28441 ggtgatgccg aggaagccga gcagggtctt caggtaaggc gtctgggtgt cggccgcggt
    28501 gccgcggtag cgcccgccgc gcgcgaaggc gacgtaggcc ttcttgccct tgagcaggcc
    28561 ctcggggcca ttctcggtgt agcggaaggt gacgcctgcg cgggcgatcg cgtcgatcca
    28621 gttcttgagc tgggtggaga tgccgaagtt gtacatcggc acacccagca ccagcacgtc
    28681 ggcggcctgc acctcggcga ccagcgcatc gctcagcgcg acgcgcgcgg cctgatccgg
    28741 gctgcgccgc tcggccgggg tgaacagcgc gccgagcgcg gcctcgtcga tcgccggtgc
    28801 ggggtcgcgg gcgaggtcgc gcaccaccac gcgggccgcg ggttggccgg cgacgaggcg
    28861 gccgacgagt tcgttggcga ggcgggtgga gttgccggcc tgggaacggg cgctgccgtt
    28921 gatctgcagg atgttcatgt gcttgtcctc tggcttgggg atgggatgaa ctgcagtcta
    28981 ttggatgcag gggattgcat taagccccct caaagcacat gattgttcct aaaatggaac
    29041 aaattgaccc caatgacctg ctcgtcttcg cccgcgtcgt ggcggagggc agcctcaccg
    29101 ccgccgccga caagctcggc ctgcccaagt ccaccgtctc gcgccggctg tcgaggctgg
    29161 aggagctgct cggcgagcgc ctgctgctgc gcaccacccg ccgcctcaac atcaccgagt
    29221 tcggcgccgc cctgctcgac cacgcccgcc agctcgagag cgaggtcgag gcggtcgccg
    29281 cgctcgccga gagccgccag gcgcgcccga gcgggcggct gcgggtgtcg atgccgagtg
    29341 acttcgccaa cctgctgctc accgacatgc tcgccgcctt cgccgcgctg catccggcgg
    29401 tgacgctgga gctcgacctg tcgccgcgcc gggtcgacct gctcggcgag aacttcgacc
    29461 tggcgatccg gctcggcgac ctgcccgatg acgcgctgct cgccgcgcgt cggctggcgg
    29521 tgtttccctg ggggctgtat gccgcgcccg cctatctcgc cgagcacggc gagccgcggg
    29581 cgccggacga cctccaccgc catcgcgcgc tgcgcctgct cgcgcgcacc ggcgacgcga
    29641 tccgctggaa cctgcgatgc ggcgagcagc gctgggaagg cgtgccgccc ggctcgatca
    29701 ccgcgaactc gccggagctg ctgatccgct tcgcctgcgc gggcgcgggc atcaccacgg
    29761 tgccggagta tttcgccgcc ccgcacgtgc agcgcggcga gctgcgccgc gtgctgccgg
    29821 actggcatcc gccctcgatc gccgcctggg cggtgttccc cggccggcgg ctgatgccgg
    29881 caaagacgcg ggccttcctg gacatgctgc aggcggcgct gggggacgag cgccacggct
    29941 gagccgggac gaggcggcgg gcggcgccgg gaacatcgcg cccgcgtgcg ggtcccaatt
    30001 cacggacgcg gctcccccgc tcgcctacaa tggcgccctt tcctcgacga ccgcacacga
    30061 tgaccctgct gcaccgcctc ctcaacctgc ccgcgcgggt gctctacctc gcgctcttcc
    30121 tggtcgcgac cgggctgctg agcttcggcc tctacctgca gcacggcctg ggcctcgagc
    30181 cctgcccgat gtgcatcatg cagcgctacg ccttcgccac cgccgcgctg atcgcgctga
    30241 tcgccggcct gcactcgccc gggcgcagcg gcgagcgggt ctacgcggcg ctgatcggcg
    30301 cgtcctcgct caccggcggc ggcatcgccg cacgccagag ctggatgcag atcgacccgc
    30361 cgctgatccc ggaatgcggg ccgggactgg agttcatgct cgagagcttt ccgctcgcgc
    30421 aggcgctgcc gatgatcttc cgcggcgcag gcgactgcac cgtggtcgaa tggaccttcc
    30481 tcggcctgtc gatcgcgaac tggtcgctgg tgagcttcac cgcgaccgtg ctgttcgccg
    30541 gctggatgct gctgcggcgg cgctgaagcg aactcagttg cagcttgccg ggccgtcctt
    30601 gacgccgagc ttgtgcagga tgttcaccag cgggcacagc ccggtgaagg cgctctggaa
    30661 caggttcagg ccgacgaagc cggtcaccca caggaagtgc ttgctgacga agagtggcga
    30721 ggcctcgacg ccgagcgcga gcgagatcag gacgaaggcg ccggcgaagg cacgcacgta
    30781 gtcattggtg gtcatgcggg attctcctcg gggttcttga ggcttgcgat gcggccacgc
    30841 atggccgcgt agtagagcac cgggatcacc accagggtga gcacggtgga cacgaagatg
    30901 ccgaagatca ggctgatggc gaggccgttg aagatcgggt cgtcgaggat gaacaccgcg
    30961 ccgatcatcg ctgccagcgc ggtgagcccg atcggcttgg cgcgcaccgc ggcggcgcgg
    31021 atcagggcct cgccgaactc catcccttcg gcgacctgct gattgacgaa gtccaccagc
    31081 aggatggagt tgcgcacgat gatgccggcg agcgcgatca tgccgatcat cgaggtggcg
    31141 gtgaattgcg cgccgagcag cgcgtggccg ggcatcacgc cgacgatggt gagcgggatc
    31201 ggcgccatga tgatcagcgg caccagatag ctgcggaact gcgccaccac cagcaggtag
    31261 atcagcacca ggcccaccgc gtaggcggcg cccatgtcgc ggaaggtctc gtaggtgatc
    31321 tgccactcgc catcccactt gagctggtag ccggcgtagg ggtcggcggg ctggcggatg
    31381 aaccattcgc cgagcgtgcc cgcaagcccc tgggcacctt cgagcgccat accattcacg
    31441 cgcgagcgga tgtcgaacat gccgtacagc ggcgagtcca gcttgccacc catgtcgccg
    31501 gtcacgtaca ccaccggcag caggtccttg cggtacagga tctgctcgcg gcgggtctcg
    31561 gccacctgca ccacctcgga gatcttcacc agctggccgg cgttgtcgcc accgcgcgcg
    31621 cgcacctgca tcgcgagcag gtcggcgagg tcggactggc gcaccgccgg cagctggatg
    31681 cgcaccggga tctcgtattt gttgtcgccg ccatgcaccg gggtgacgtt ctcgccggag
    31741 agcccgagac gcaccacctc gacgatgtcg gcctgggcca cgcccatgcg cgcagccttg
    31801 gcctggtcga cgcgcagcac cagcttgggc gcgtcctcgt ccaccgtgtc gtcgacgccg
    31861 acgatgtccg gggtgtcctc gaaggcggca cgcacgcgcc tggccacttc aacctggccg
    31921 tcgtagtcgg ggccgtagat ctcggcgacg atcggcgaca gcaccggcgg gccgggcggc
    31981 acctcgacga ccttggcgtt gccgccgttg cggcgcgcga tctcggtcac cgcgtcgcgc
    32041 accgacaccg cgatctcgtg gctctggcgg tcgcgtgcgg tcttgtcgac caggttgacc
    32101 tggatgtcgc cctgctcggg cgcgctcctc aggtagtact ggcgcaccag gccgttgaag
    32161 ttgatcggcg cggcggcacc ggcgtaggac tgccagtcgg tgacctcggg gacggtggcc
    32221 agatgggcgc cgatctcgtt gagcacgcgc gcggtgtcct cgaccggcgt gccgaccggc
    32281 atgtcgagca cgacctgaaa ctcgctcttg ttgtcgaagg gcagcatctt catgaccacg
    32341 agctgcacca ccggcagcgc caccgaggcg ccgatgagcg cgaacaccac cagccacagc
    32401 atcagccggt tgcggccgcc gcggcgggcg tcgaacatcg gcgtcatcac gccacggaag
    32461 aggccgtcga gccgcttcgt catcctgtcc tcgccgccgt gctggtgggc gtcgacgttc
    32521 ttcaacatct tctgcgccag ccagggcgtg accacgaagg ccaccaccag cgagatgaac
    32581 atgcccatcg atgcgttgat cgggatcggg ctcatgtagg ggcccatgag gccggtcacg
    32641 aaggccatcg gcagcagcgc ggcgatgacg gtgaaggtgg cgaggatggt gggaccgccg
    32701 acctcgtcca ccgccttggg aatcagcttc cacagcggcg tgtcgggctc gagcgtgtgc
    32761 cagcggtgga tgttctccac caccacgatg gcgtcatcca ccaggatgcc gatcgagaag
    32821 atgagcgcga acagcgacac ccggttgagc gtgaagcccc aggcccagga cgcgaacagg
    32881 gtcgccgcga gcgtgagggt gaccgcgatg ccgacgatga tcgcctcgcg ccggccgagc
    32941 gcgaagaaca ccagcgccac caccgccgcg gtggcgaagg cgagcttgcc gatgagctgg
    33001 ttggccttgt cgttggcggt cttgccgtag tcacgggtga cggtgacctc cacgccctcc
    33061 gggatcaggc tgccgcgcag gttctccagg cgctgcatcg ccgcctgggc gacgtcggcg
    33121 gcgttggcgc cgggcttctt cgacagcgcc agggtgaccg cggggaacag gccctgctcg
    33181 tcgatgccgc gctgctcggc ggcggcgccg gtgccgaacc agacgtactg cgacggctgg
    33241 tcggggccgt cgacgacctc ggcgacgtcg cgcaggaaga ccggcttgcg gtcctgcacg
    33301 cccaccacca gcctgcgcac gtcctcggcc gattcgagat aggtgccggt ctgcaccagc
    33361 acctcgcggt tgcccgcgac caggctgccg gccggctgcg aggcgttggc gagctgcagc
    33421 gcgccgcgca ggtcctgcgc ggtgacgccg tgcgcgttca tgcgctcgat gtccatgttc
    33481 acccggatca cgtggccagg gccgccgagg gtggcgacgt cgcgggtgcc ggggatgcgc
    33541 tttagttccg tctcgatcgc gcgcgagacc tgctgcagcg aaaacgccgc gcgcgcgggg
    33601 tcgggcgtcc acagcgtaaa gctgacgatg ggcacgtcgt cgatgccctt gggcttgatc
    33661 agcggcttgc cgacgccaag ttgcggcgac agccagtcgg cgtgcgagtc cacggtgtcg
    33721 tagagccgca ccagcgcggt ctggttgggc acgccgacct cgaactgcac ggtgatcacc
    33781 gccatgccgg ggcgcgacac ggtgtagacg tgctcgacgc cggcgatgcg cgacagcacc
    33841 tgctcggccg gccgcgccac cagggcctcg acatcgcgcg ccgaagcgcc cgggaagggc
    33901 accagcacgt tggccatggt gacgtcgatc tggggctctt cttccttggg cgtgatcagg
    33961 gtggcgaaga tgccggcgag cagcagcacc agggcgagca gcggcgtgat cgcgttgcgc
    34021 tggaagccgg ccgcgatgcg gccggagatg ccgaggggct tgtccatgac ggtctcccgg
    34081 ctcagcgcgc ggccgcggcc gcgcggacct ggatgccggc ctggaccggg tcgagggcga
    34141 gggtctcgtc acccttgagg ccggagagca cctccaccga ctcgccaccg ggcagcgcac
    34201 gaccgaggcg gacctggcgc agcgtgaagc cgccctgccc gtcggccgca tacacggcgg
    34261 tgagttcgcc gcggcgcagc accgcggccg cagggatcac gacggggccg gcggcggccg
    34321 gggcggcggc gccatggaaa tgcactcgcg caaagctgcc ggggagcacg tcctccacgc
    34381 cggcgggcag atccacccgc acgcgcacgg tgtgggtgcg ggcgtcggcc gcgggcagca
    34441 cggtcaccgc cgcagcttcg atgacgcgcc cgctcgcggg cagctcgacg ctggcgcgca
    34501 gcgggccggc gccgagctcg gcgaggcgct gcggggcgag atcggtcacg gcgcgcatct
    34561 gcgcggggtc gtagacggtg agcaggttgc gcccgggctg cgccatctcg ccaggctcga
    34621 tgtggcgcgc ggcgacgagg ccgtcgagcg gcgacaccac gctggcgtag cccttcacgg
    34681 tggcggcctg ctcgcgctgg gcgcgcgcgg cgcgcacctg agcctcggcg gcctggaact
    34741 gcgcacgcgc attgtcgagc gccgactggc tgaggaactt gcgctcgacc aggctgcgcg
    34801 cgcgctggta ctccgcgcgc gcgttggcga gcgcgctctc ggcctgcgca atgcccgcct
    34861 cggccgcggc gaccgcggca gcggcctcgg caggatcgat gcgcgccagc agcgccccct
    34921 tgcgcacacg atcgcccgcg tcggcggaga gctcgaggat gcgcccgggc atctgcgcgg
    34981 ccagggtgga ctggcgcacg gcctcgacgg tggcctcggc ggcgatcaca ggcacgacgg
    35041 cgcgtgcctc gatgcgaacg gtgggaacct ccgcacgcgc cgcgccggag gtggcgacga
    35101 acaggctcag ggcgaggacg gctgcaatac gcgcaggagt ggggagcatg atcggcttca
    35161 taagaataag tatattctta tattgaaggc cgtcaaggaa tacccctcgc gcatccacgg
    35221 ggatcgcgcc tccgcgccgg gacaaggcgg cccgcgcccg ggcgcaattg atgcgccggc
    35281 gaagctcgat gcctcgagac cgcgggcggg cgtcaggccc gcttcggcgc cagcgcggat
    35341 ttcacgcgcg gaagcttgcc gactcagagc ctgagaagca tttgatttcc gcaagccgag
    35401 taaccgacat gcgat
//
LOCUS       DAOTIN010000025        34498 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_1382_length_34498_cov_8.963737, whole genome shotgun sequence.
ACCESSION   DAOTIN010000025 DAOTIN010000000
VERSION     DAOTIN010000025.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 34498)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 34498)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34498
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1382_length_34498_cov_8.963737"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(173..1552)
                     /locus_tag="P5537_05915"
     CDS             complement(173..1552)
                     /locus_tag="P5537_05915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HRV77614.1"
                     /translation="MTSSDLRAAIARGSRRRGPLLAACALALAVLAPPVAGQDNAPAP
                     LPATSLRIGDAAEGTLAAMPAPETARVLTLDLTRDAHDIWDRIRRGFGMPDLDSQRVM
                     DQQSFYLNRPRFLKQVFERGGRYLYYIVDELERRGMPTEIALLPMVESSYNPMAYSRA
                     HASGLWQFIPSTGKHYNLTQDHWVDERRDVIASTNAALDYLQRIYEMHGDWHLALASY
                     NWGEGAVQRALKRNAEDGLPLEYEHLRMPDETRNYVPKLQAIKNIVSEPELFHFELPY
                     VANELHFVSVEAPIGVDLATAAKLSGMPLDEFLALNPSFNRPAVTTPGQIFIVPTDRA
                     EQLQQGLAELDEDDGEWRMHVMAAGETLEAVAARHGLSSAELRKLNGLGPGSRPGEGY
                     SLLVPDGIDPDGALEVTSLLPLAATAARQPGLKLNTSKARSGEPRLKSPKTKARPGEK
                     RSAKRSKKR"
     gene            complement(1559..2332)
                     /gene="gloB"
                     /locus_tag="P5537_05920"
     CDS             complement(1559..2332)
                     /gene="gloB"
                     /locus_tag="P5537_05920"
                     /EC_number="3.1.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004416 - hydroxyacylglutathione hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0019243 - methylglyoxal catabolic process
                     to D-lactate via S-lactoyl-glutathione [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacylglutathione hydrolase"
                     /protein_id="HRV77615.1"
                     /translation="MDIIPIPAFRDNYIWLVHDGRHALVVDPGDATPVEEALREHGLT
                     LTAILVTHHHPDHTGGIGALVASHRVPVYGPARESIAGVVHAVADGDEIHLPAPALTL
                     RVLDVPGHTAGHVAYVGMDIEPGLVFCGDTLFSAGCGRLFEGTPAQLGRSLARLAALP
                     PDTRVYCTHEYTLSNLAFARAAEPDNAERDAWAAHCEALRARGEPTLPSTIARERAIN
                     PFLRCEQPGVIEAVAAQAGSRPQDALECLAALRAWKDRF"
     gene            2361..3086
                     /locus_tag="P5537_05925"
     CDS             2361..3086
                     /locus_tag="P5537_05925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HRV77616.1"
                     /translation="MSILRLEEWLQTPQGRYLLDWEQDGLDRLVADIFGYHAVQLGLP
                     GLELLRANRMPRRINCGPQGRDLCCSEYELPFATGSLDLVLLPHVLEFSAHPHRVLRE
                     VERVLVPEGSVVISGLNPISLWGLRRLVARRGAEAPWSGHYRSAMRIRDWLTLLGFEI
                     QESRFGCYAPPLRTPRWLERWRCIDRAGSRWWPVLGAGYLLHGIKRVQGMRLITPHWR
                     GRKAVAKRLSPVAQRDGSTRNMQ"
     gene            3089..3547
                     /gene="rnhA"
                     /locus_tag="P5537_05930"
     CDS             3089..3547
                     /gene="rnhA"
                     /locus_tag="P5537_05930"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI"
                     /protein_id="HRV77617.1"
                     /translation="MEEVDIYTDGACSGNPGPGGWGAILRSGAHEKEIWGGEPATTNN
                     RMELLAVIRALEALKRPVAARVHTDSQYVQKGISEWIHGWKARGWKTASKEPVKNADL
                     WRALDEAASRHQVKWLWVRGHNGHPENERADALARRGVDAVRKSGAVVEC"
     gene            3561..4286
                     /gene="dnaQ"
                     /locus_tag="P5537_05935"
     CDS             3561..4286
                     /gene="dnaQ"
                     /locus_tag="P5537_05935"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit epsilon"
                     /protein_id="HRV77618.1"
                     /translation="MRQIVLDTETTGLDWRNGDRVIEIGCVELLDRGLTGRHYHVYIN
                     PGRGIDAEAVAVHGITEEFLADKPKFSDIVADFEDFVRDAELVIHNASFDVGFLDAEL
                     DRLGRARLGVLCAGVIDTLKLAKEQNPGKKASLDALCDRYEIDNAHRELHGALLDAEL
                     LAEVFLAMTRGQESLMIGLDDEPSAREADSEGAPLLRAAIPVLRASAEECTAHDAVLA
                     EIAKANKGLCLWLPPEGDPAQAG"
     gene            complement(4401..4811)
                     /locus_tag="P5537_05940"
     CDS             complement(4401..4811)
                     /locus_tag="P5537_05940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HRV77619.1"
                     /translation="MMLGSLLVKDYMVGDHLAFSPNTDLLKAVHLLLKRGLSGAPVVD
                     ENQRLVGFLSEKDCLKAALDASYFRRDEGTVEDFMSRDVTSISASASLIDAIELFLSK
                     NYRSLPVVEGSRLIGQLSRHDILKGLEKVRRDER"
     gene            complement(4824..5027)
                     /gene="nqrM"
                     /locus_tag="P5537_05945"
     CDS             complement(4824..5027)
                     /gene="nqrM"
                     /locus_tag="P5537_05945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(Na+)-NQR maturation NqrM"
                     /protein_id="HRV77620.1"
                     /translation="MNTFLITLLVVGLVILAMAIGVLFGRKPIAGSCGGLGAMGQDCE
                     FGCKKPCSKRQARALAAQAEQQH"
     gene            complement(5151..5921)
                     /locus_tag="P5537_05950"
     CDS             complement(5151..5921)
                     /locus_tag="P5537_05950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused MFS/spermidine synthase"
                     /protein_id="HRV77621.1"
                     /translation="MNLPIDISEEAGVRYLHFGSDWIQGAMRIRKPYALELAYTREMM
                     AGLLLRDGLAADGAHWPRKVLIIGLGAASLARFVHHHLPQARIRVVEIAPAVVAAARQ
                     FFKLPTEDARFSVHIGCGAQFVLEHDEEWDYVLVDGFDRNARAGVLDTEPFHQAVRAR
                     LSARGIMAVNLFGRSRGYKASLERIVRAYEDRALAFPSCDSGNVVAFGAAGEPIERAV
                     EELRERARQLKTETGLDLLPTVTRLEVAGSLPGGVLRM"
     gene            complement(6036..8666)
                     /gene="mutS"
                     /locus_tag="P5537_05955"
     CDS             complement(6036..8666)
                     /gene="mutS"
                     /locus_tag="P5537_05955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014237301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HRV77622.1"
                     /translation="MMQQYLRIKQQHPDTLLFYRMGDFYELFFDDAEKAARLLDITLT
                     TRGQSGGKPIRMAGVPFHAVEQYLARLVKLGESVVIAEQVGEPGATKGPMERAVSRIV
                     TPGTLTDAALLDDRRDSLLLAASLHRGVLGLAWLNLANGDFRLMQCPSDALQAQFERL
                     RPAEVLVPDGLALPLLDALAPAQRRLADWQFDAETGTRLLTTHFGTRDLAGFGVEDLP
                     VALGAAAALYDYAQATQRQTLAHVTGLVVERESETLRLDAATRRNLELTETLRGESSP
                     TLLSLLDTCVTSMGSRWLRHALHHPLRERAEPAARHAAVAELVGAAEADMNVEAGGTG
                     GGAVAQGAGAAGLALAGRDGRVAFAVRGALRGVADVDRITARIALRSARPRDLSALRE
                     SLLRLPELAAALAPCRAPLLAEIVGALAIAPEPLALLQHAIAAEPAAMVRDGGVIAPG
                     FDAELDELRGIQTNCGEFLMALETRERERSGIPGLKVEFNKVHGFYIEVSRANADKVP
                     DDYRRRQTLKNAERYITPELKAFEDKALSANERALAREKLLFDQVLDVLAAHIPTLQR
                     IARALALLDGLAALAEAALRYGYVQPRFVDTPGLNIVGGRHPVVERQVESFIRNDARL
                     AATRRMLMITGPNMGGKSTFMRQVALICLLAHVGSFVPADAAELGPLDAIFTRIGASD
                     DLASGRSTFMVEMTEAAAILHGATERSLVLMDEIGRGTSTFDGLALAFAIARHLLEKS
                     RALTLFATHYFELTRLNADYPECANVHLDAVEHGHRIVFLHALEEGPASQSYGIEVAA
                     LAGIPATVIRDAKRRLRALENREIDAGPQADLFADLPEPEDAPLSHPVLTELADIDPD
                     ALTPREALERLYALKRLAAG"
     gene            8827..9357
                     /locus_tag="P5537_05960"
     CDS             8827..9357
                     /locus_tag="P5537_05960"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02281 family clan AA aspartic protease"
                     /protein_id="HRV77623.1"
                     /translation="MNTPDADTRRIGRRLGLLATLAFLALGWVSFDGAIERREDPNRN
                     LVVAPGASELVLQRNRAGHYLLPGEINGRPVRLLLDTGATQVSVPARLAAELGLQAGA
                     PASVRTANGAVTVRQTRIPRLAFGPFEFRDVAGHLNPGMQGDEVLLGMSALRHLEFTQ
                     RGDTLTLRAPGSPGAS"
     gene            complement(9368..10168)
                     /locus_tag="P5537_05965"
     CDS             complement(9368..10168)
                     /locus_tag="P5537_05965"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008934 - inositol monophosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006020 - inositol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046855 - inositol phosphate
                     dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HRV77624.1"
                     /translation="MHPTLNIAVKAARRAATVINRASTQLDLLTVQSKSPNDFVTEVD
                     RAAEQAIIEVLRDAFPGHGILAEESGESGPESEFTWIIDPLDGTTNFIHGMPQYAVSI
                     AQTKNGVLEHAVVYDPNTNEMFTASRGAGAFLNDRRIRVSRRTRLNESLIGTGFPFRQ
                     FDHVDAYLAMFKELTQKTAGIRRPGAASLDLAYVAAGRFDGFWEMGLSPWDMAAGVLL
                     IQEAGGLVSDLSGEANYLATGNLVAGSPKIFGQLLPIIQAWRPANLQA"
     gene            10312..11049
                     /locus_tag="P5537_05970"
     CDS             10312..11049
                     /locus_tag="P5537_05970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HRV77625.1"
                     /translation="MNRPLALDRIRVVLSRTSHPGNIGAAARAMKTMGLRELWLVAPE
                     SFPDEVASARASGAADLLEKARVVDTLEEALADTVFSAALTARRRELSLPRLQARDAA
                     VELVGRTQDGAVALVFGNETSGLTNEEAALCSLPVTIPTDAEFSSLNLGAAVQVLAYE
                     LRMAALGDAAAPADPQPEPATHADFEGFMAHLERAVTASGFHDPANPKRLLPRMRRLF
                     NRVRLEREEVALLRGMLTTFETPRRRG"
     gene            11482..12237
                     /gene="cysE"
                     /locus_tag="P5537_05975"
     CDS             11482..12237
                     /gene="cysE"
                     /locus_tag="P5537_05975"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002932476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HRV77626.1"
                     /translation="MFSRLREDLASVRERDPAARSTLEVLTCYPGIHALMFHRLAHGA
                     WRRGWFWAGRFASHIGRLLTGIEIHPGARIGRRVFIDHGMGVVIGETAEIGDDCTIYQ
                     GVTLGGTSLYRGTKRHPTLGRGVVVGAGAKVLGGFTVGDGAKVGSNAVVVKPVPAGAT
                     AVGNPARILDSERDAAREQKAEQIGFSAYGVTRDMDDPVAKALHGLLDHSVETDRRLQ
                     AILARLEAAGIKLDDTVAPNDDFDPGRLSRMVD"
     gene            12648..13130
                     /gene="iscR"
                     /locus_tag="P5537_05980"
     CDS             12648..13130
                     /gene="iscR"
                     /locus_tag="P5537_05980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003690 - double-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly transcriptional regulator
                     IscR"
                     /protein_id="HRV77627.1"
                     /translation="MRLTTKGRFAVTAMIDLAARQGDGPVTLAGIAERQSISLSYLEQ
                     LFGKLRRHKLVNSVRGPGGGYRLARAMDEITVADIIIAVDEPMDATQCGGKENCHDDH
                     VCMTHHLWSNLNQRIYAYLDSVSLEALVKHQVRPDPDMTVLKSVRRRSRMPVHEIAAV
                     "
     gene            13143..14306
                     /locus_tag="P5537_05985"
     CDS             13143..14306
                     /locus_tag="P5537_05985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HRV77628.1"
                     /translation="MSFTPAYLDWNATTPLDPAVREAMLPWLGAAEPVRFGNASSRHE
                     YGRQARAAVDEARTRVAEAVGAHATEVIFTSGGSEANNLFLKGAAPNLKPGVVAVSAI
                     EHPCVREPARQLRRAGWTLREIGVDDQGRIDLADWAAVLESRPGLVSVMLANNETGVL
                     QDVAALAREARTSGAWFHTDAVQGLGKVAVDFRALGVNAMTLSAHKIGGPLGAGALVV
                     DKRVELAPLIAGGGQERGLRSGTENVAAIVGFGVACTRAVARREAEAVRLAALRDELC
                     AALAGRGARIFSVAAPRLPNTVFFAVEDIDGETLVGRLDRAGFACASGSACSSANPEP
                     SHTLLAMGVEPGLARAAVRVSLGRDTRADDVHSFIETFVRVTDELKSLASIGA"
     gene            14364..15575
                     /locus_tag="P5537_05990"
     CDS             14364..15575
                     /locus_tag="P5537_05990"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004333245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0044571 - [2Fe-2S] cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IscS subfamily cysteine desulfurase"
                     /protein_id="HRV77629.1"
                     /translation="MLKFPIYLDYSATTPVDPRVAAKMIPWLTEHFGNPASRSHAYGW
                     EAEKAVEDAREQVAALVNADAKEIIWTSGATESNNLAIKGAAHFYQGKGKHIITVKTE
                     HKAVLDTVRELEREGFEATYLDVQENGLIDLEVLKAAIRPDTIVVSVMFVNNEIGVVQ
                     PIAEIGELCREKGVVFHVDAAQATGKVDIDLDKLKVDLMSFCAHKTYGPKGIGALYVR
                     RKPRVRLEAQMHGGGHERGLRSGTLATHQIVGMGESFRLAREEMAEENARVGKLRDRL
                     LAGLTDLEATYVNGDLEQRVPHNLNISFAYVEGESLIMAVKDIAVSSGSACTSASLEP
                     SYVLRALGRNDELAHSSIRFTIGRFTTEEEIEYTIKLLHDKIGKLRELSPLWEMYKDG
                     VDLDAVQWAAH"
     gene            15642..16025
                     /gene="iscU"
                     /locus_tag="P5537_05995"
     CDS             15642..16025
                     /gene="iscU"
                     /locus_tag="P5537_05995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004315115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold IscU"
                     /protein_id="HRV77630.1"
                     /translation="MAYSEKVLDHYENPRNVGSFGKEEDGVATGMVGAPACGDVMKLQ
                     IKVGKDGVIEDAKFKTYGCGSAIASSSLVTEWVKGKTLDQALEIKNTQIAEELALPPV
                     KIHCSILAEDAIKAAVADYKKKHEA"
     gene            16052..16375
                     /gene="iscA"
                     /locus_tag="P5537_06000"
     CDS             16052..16375
                     /gene="iscA"
                     /locus_tag="P5537_06000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017904917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster assembly protein IscA"
                     /protein_id="HRV77631.1"
                     /translation="MAVTLSESAARHVSNFIAKRGKGFGIRLGVKTSGCSGMAYKLEF
                     VDQTEDEDEVFESHGVKVVIDPKSLAYLDGTELDFVKEGLNEGFKFNNPNVKDQCGCG
                     ESFNV"
     gene            16386..16919
                     /gene="hscB"
                     /locus_tag="P5537_06005"
     CDS             16386..16919
                     /gene="hscB"
                     /locus_tag="P5537_06005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004315113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051087 - chaperone binding [Evidence
                     IEA];
                     GO_process: GO:0051259 - protein complex oligomerization
                     [Evidence IEA];
                     GO_process: GO:0097428 - protein maturation by iron-sulfur
                     cluster transfer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S protein assembly co-chaperone HscB"
                     /protein_id="HRV77632.1"
                     /translation="MSIDLTQDYFALFGLPRRYALDEGALEAAWHELQGRVHPDRHAH
                     LSDFEKRRSMQWATRVNEGFRVLRKPLARAQYLLELAGVDAALETNTAMSAEFLMEQM
                     EWREAVEEAREAAEVSELEDLHRRLLGHAREVRGHLAAQLDEHQDYEAAADTVRRLMF
                     IDKLQQEIDEALLALEN"
     gene            16948..18816
                     /gene="hscA"
                     /locus_tag="P5537_06010"
     CDS             16948..18816
                     /gene="hscA"
                     /locus_tag="P5537_06010"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S protein assembly chaperone HscA"
                     /protein_id="HRV77633.1"
                     /translation="MALLQITEPGMSTEPHKHRLAVGIDLGTTNSLVATVRNGIAICL
                     PDEAGRTMLPSAVRYQADGGIEVGLGALKAQAVDPRNTIVSVKRFMGRGLKDVAHIEA
                     MPYDFEDSPGMVRLRTVQGVKSPVEVSAEILRRLRERAEASLGGALVGAVITVPAYFD
                     DAQRQATKDAARLAGLDVLRLLNEPTAAAVAYGLDNAAEGVYAVYDLGGGTFDLSILK
                     LSRGVFEVLSTNGDAALGGDDFDHRLFCWILDRAKISPPSLEDARRLQMKAREAKELL
                     TSCDEAPVHVRLGSGEEVDLVVTREEFAEMTTHLVQKTLAPVRKALRDAGLAPDEIKG
                     VVMVGGATRMPHVQRAVANYFGQEPLTNLDPDKVVALGAAMQANVLAGNRADQDDWLL
                     LDVIPLSLGLETMGGLVEKVVPRNSTLPIARAQEFTTFKDGQTAMAFHVVQGERELVS
                     DCRSLARFELRGIPAMVAGAARIRVTFQVDADGLLSVSAREMSSGVEASVLVKPSYGL
                     SDDEIAEMLRSGVDHAGDDMAARALREQQVEADRVVEATEQALAHDGHLLSASEAEEI
                     RSVIARLRELRAGNDNRAIKAGIDALARATDTFAARRMDNSIRSALAGHKVDELPI"
     gene            18827..19168
                     /gene="fdx"
                     /locus_tag="P5537_06015"
     CDS             18827..19168
                     /gene="fdx"
                     /locus_tag="P5537_06015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004315110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISC system 2Fe-2S type ferredoxin"
                     /protein_id="HRV77634.1"
                     /translation="MTQIIVLPHVELCPDGSVLEAAPGTTICDALLDNGIDIEHACEK
                     SCACTTCHVIVREGFSSLNSAEDEEEDLLDKAWGLEPQSRLSCQAVVASTPLVVEIPR
                     YTINMAREGKH"
     gene            19170..19364
                     /gene="iscX"
                     /locus_tag="P5537_06020"
     CDS             19170..19364
                     /gene="iscX"
                     /locus_tag="P5537_06020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein IscX"
                     /protein_id="HRV77635.1"
                     /translation="MKWTEVQEIAIQLTDAHPDVDPTRVNFVDLMNWVMALPDFDDDP
                     KRCGERILEGIQQAWIDEVA"
     gene            complement(19518..19976)
                     /locus_tag="P5537_06025"
     CDS             complement(19518..19976)
                     /locus_tag="P5537_06025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV77636.1"
                     /translation="MASERPILLVEDNPDDEALTLHALSRNRISSPVVVAHDGVEAVE
                     YLFSTGSRAGQTLPPLPAVVLLDLKLPRIDGLEVLRRIRADQRTALLPVVVLTTSREP
                     LDLAQAYRLGANSYIRKPVDFDRFERAIGLIGHYWLELNETTETVARGAY"
     gene            complement(20022..20981)
                     /gene="prmB"
                     /locus_tag="P5537_06030"
     CDS             complement(20022..20981)
                     /gene="prmB"
                     /locus_tag="P5537_06030"
                     /EC_number="2.1.1.298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008276 - protein methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA];
                     GO_process: GO:0042273 - ribosomal large subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3 N(5)-glutamine
                     methyltransferase"
                     /protein_id="HRV77637.1"
                     /translation="MPETHHDDAPDHELEQNPDHEHEHEHGPLAELVTVRDWLRYAVT
                     RFNRAGIFCGHGVHDSFDEAVWLILGTLALPLDRLEPFMDACIPSEERIALLEAIEQR
                     ADERIPTAYLLGEAWLGDFRFTVDSRVIVPRSFFAELLEDGFAPWVEDPEAVVSALDL
                     CTGSGCLAILMAHAFPNAEVCAVDLSEDALEVARINVADYGLQDRIELVHGDVFEGLE
                     GRRFDLILSNPPYVTAEAMDALPPEYLHEPQMALASGEDGLDVVRRLLAEAADHLNPG
                     GILAVEVGHNRDIVEAAFPDLPFQWLSTRGGDDMVFLLHREDL"
     gene            complement(21173..22330)
                     /gene="dapE"
                     /locus_tag="P5537_06035"
     CDS             complement(21173..22330)
                     /gene="dapE"
                     /locus_tag="P5537_06035"
                     /EC_number="3.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009014 - succinyl-diaminopimelate
                     desuccinylase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinyl-diaminopimelate desuccinylase"
                     /protein_id="HRV77638.1"
                     /translation="MQTSLSSTPTLALACELIARPSVTPEDAGCLELLASRLAPLGFR
                     IERIDTGGVCNLWARRGDSAPVLCFAGHTDVVPPGPDAAWSSPPFVPTIRDGVLYGRG
                     AADMKSSLAAFVTAIERFVAAHPDHAGSIALLLTSDEEGIATHGTVKVVEALAARGER
                     LDYCVVGEPTSVKTLGDMIKNGRRGSLSGTMRVKGQQGHVAYPQLARNPIHLFAPALA
                     ELAAIEWDQGNEFFPPTTWQVSNIHAGTGANNVIPGVCEVMFNFRFGSVSSADELKRR
                     TCEVLDRHGLEYEIDWHLSGKPFITGRGKLVGALSAAIRDTLGVDTELSTSGGTSDGR
                     FIAEICAEVVEFGPVNASIHKIDEHIAADAIEPLSAVYQRTLAALLASASL"
     gene            complement(22355..23527)
                     /locus_tag="P5537_06040"
     CDS             complement(22355..23527)
                     /locus_tag="P5537_06040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043107 - type IV pilus-dependent motility
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilT/PilU family type 4a pilus ATPase"
                     /protein_id="HRV77639.1"
                     /translation="MIFDNLFQLMAEKKASDIFITAGTPIHIKIQGHTMPINQQVMDP
                     LMIQRMLHEAITPAQQSVLDRERELNLSFGRRDLGNFRVNVFWQRNSMAVVVRYIQSD
                     IPSIGALGLPPVLDDIVLEKRGLVLVVGATGSGKSTTLAAMIDHRNRNRSGHILTIED
                     PIEYLFKHRKSVVNQREVGIDTLSWGEALRNAMRQAPDCILIGEIRDRETMQAAISYS
                     QTGHLCLATLHANNAYHALNRIVNFFPLENRQLLYLDLAVALRCVISQRLVRKPDGKR
                     IPAVEILMNTRHIAELVERGELNAIKEAMEQSLAQGSQTFEQALYRLHHENIITLDEA
                     LANADSPSNLHWLINNAQMQSDPMLTVNGNTSITGFEATNTDGASFQEFTLDLNNN"
     gene            complement(23876..24697)
                     /gene="dapD"
                     /locus_tag="P5537_06045"
     CDS             complement(23876..24697)
                     /gene="dapD"
                     /locus_tag="P5537_06045"
                     /EC_number="2.3.1.117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008666 -
                     2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-succinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-succinyltransferase"
                     /protein_id="HRV77640.1"
                     /translation="MHALQSIIDTAFENRASLSPAAAPAEIRNAVEEVIAGLDAGTLR
                     VAEKKDGQWVVNQWIKKAVLISFRLRDNEVVQAGGLNFFDKVATKFGDYTPEQFREGG
                     FRVVPPAVARKGSFIGRNVVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
                     GVGIGGVLEPVQAGPVIIEDNVFVGARSEVVEGVIIEENAVLSMGVYIGMSTKIYDRE
                     TGEVTYGRVPAGAVVVPGSLPSACGKYSLYCAVIVKRVDAQTRAKTGINELLRGA"
     gene            complement(24712..25905)
                     /gene="dapC"
                     /locus_tag="P5537_06050"
     CDS             complement(24712..25905)
                     /gene="dapC"
                     /locus_tag="P5537_06050"
                     /EC_number="2.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009016 - succinyldiaminopimelate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019877 - diaminopimelate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinyldiaminopimelate transaminase"
                     /protein_id="HRV77641.1"
                     /translation="MNPNLARLQSYPFEKLRALFADVEPPAHLKPIRLSIGEPQHPTP
                     GFIRQTLADNLGGLSSYPATLGSDALRGAIAHWLERRYGLPKIDPASQVIPVAGTREA
                     LFAFAQCVVDGGRPGAKVLCPNPFYQIYEGAALLANAEPIFINNLPENDFGSDFSSID
                     EATWRDIQLVYVCSPGNPTGRLLKLDEWKTLFELSDRYGFVIAADECYSEIYFDDADK
                     PIGGLEAAWRLGRTDFRNVVMFSSLSKRSNVPGMRSGFVAGDARILKDFLLYRTYHGC
                     ALNPAVQAASVVAWNDEEHVEENRRLYRDKFARITPMLQPWLPVSLPDAGFYYWVRTP
                     IPDTEFARRLQAEYNVTVLPGSYLAREANGVNPGAGFVRIALVADTHECVEAAARIID
                     FCKTL"
     gene            26169..29879
                     /locus_tag="P5537_06055"
     CDS             26169..29879
                     /locus_tag="P5537_06055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HRV77642.1"
                     /translation="MRLSKLKLAGFKTFVDPTTVLTPGNLVGVVGPNGCGKSNIIDAV
                     RWVLGETRASALRGESMQDVIFNGSTTRKPVSRASVELVFDNAEGRAAGQWSRYAEIS
                     VKRVLDRSGESTYYINNVHVRRKDVIDLFLGTGLGPRAYAIIEQGMISRIIEARPEEI
                     RGFLEEAAGVTKYRERRKETEGRLRDARDNLARLDDIRMELGERIVHLEAQAAVAARY
                     RALDAAHVEKQQLLWLVKRNEARAEHGRVAAALDEASRRIEADSARLQELEAGVEARR
                     DAHFEASEAVHVAQNDLFAVSAEVARLETELQHLGEARKRLEARLAQLELDRGHWSSR
                     REALAADRERWQALAENAALRAEHAEARHLEIADRLPELDSARQAADATMAAARRELA
                     QTEQQLRVEETRRASAVRALEALQQRRGRLEGERGAIVGPDERVLAEREARLEVVQDE
                     LEALQQALAEAQPRLPDAQAALKAALEHERAVQRRLTELRARRDALVQLQARVQSQGK
                     LGDWLKRHGLDALPPLWKQLQVEDGWDEAVQAVLRERLSALTSPDAAVALAAAHTVLD
                     ETPPESLAIALPVTPSTLDPAACFAPAAAPASSTETPPPVGAPAGANACDEATHPSAT
                     AFALSGGPGPSAEAPPLVGAPAGANARALARLVAVRDPALRGLVGDFLAGAWAVERLD
                     DWLPRCAQLAPSTCLVGPRGQILTRGALIHHAPDARTHGVIERQREIEGLAAELQARE
                     DEAHLAHDALLMAETAASELQERINGLRRELQTLQAQVHAEQVEVLKLAQARARAEER
                     REQLARDLEDIVHLETAEREHLTRAELEQARAAELAELQRERLDAATEVLREREHAVR
                     EARALEQSAARELQEARFSERECAGKLEDIARNQQLAGEQLERIVAELATRSAELDAT
                     DDHRSADALQEALALRGRREAALAARRDALAEAAAALKQVEELRLRTEHEAAPIRARV
                     AELRLALQAAEIAVAQFEERLVEARADETALQPLLAADPKESTLQREVARLAREIAEL
                     GAVNLAALDELATASERKGYLDAQTEDLLQAIDTLEDAIRRIDRETREQLQDTYNTVN
                     RQFGALFPQLFGGGRAELVLTGEEILDAGIQIVAQPPGKKNASIHLLSGGEKALTAIA
                     LVFSMFQLNPAPFCMLDEVDAPLDDTNTERYANMVKRMSAQTQFIFISHSKITMEFAQ
                     QLVGVTMQEQGVSRVVEVDIEEALRLADPAAA"
     gene            29917..30999
                     /locus_tag="P5537_06060"
     CDS             29917..30999
                     /locus_tag="P5537_06060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004375780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZipA C-terminal
                     FtsZ-binding domain-containing protein"
                     /protein_id="HRV77643.1"
                     /translation="MDSELQIALIGAGIAAVVLVVGYNKWQERRHRREAERAFKSEHR
                     DVLLEPREEPVAGERREPGIGAAEGEPRRFNEAPMKRSTPELPRLLDPRADCVIRLET
                     IEALEVGRVWAIQAEQLAGLAKPVYWFGFNDAENVWQPLGPDSGGACHWFCAALQLVN
                     REGSIGETDFMRFSGGVQRVADALMSLPPALPPRAETLRNATELDRFCADVDVQIGVN
                     VVARDGQFEGRAIHAVAEKHGLRLGADGAYHMVDGEHSVFAVANLESGRFSPESLKGL
                     VTRGLTLVIDVPRVANGGAAFDRMMKMATTLAGELGGDVVDDNRAPFGAEAAAIIRGQ
                     IGQFQSRMADHDIPAGSPLALRLFSV"
     gene            30999..33080
                     /gene="ligA"
                     /locus_tag="P5537_06065"
     CDS             30999..33080
                     /gene="ligA"
                     /locus_tag="P5537_06065"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004333278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HRV77644.1"
                     /translation="MDLSADNSPAASAGEVAARAAALRAEIARHDHAYYVLDAPTIPD
                     AEYDRLFRELQAIEQVHPALRSADSPTQRVGGKPLAQFAAVRHRIPMLSIRTETDTEA
                     SGAFVFDSRVRSALKRNDEDPPIEYAAELKFDGLAISLRYEDGVLVQAATRGDGETGE
                     DVTANVRTVKAIPLRLRGEAPPVLEIRGEVYMRRDDFERLNTRQADAGDKTFVNPRNA
                     AAGSIRQLDPSIAARRPLSFFAYGLGDTGEWTPPATHAEVLDVIAAFGLPVCEHRAVV
                     QGAQGLADFHARMGALRDTLPFDIDGVVYKVNSRALQQQLGFVTREPRWAVAHKYPAQ
                     EAVTLLRDIEVQVGRTGALTPVARLEPVFVGGVTVTNATLHNQDEIDRKDVRIGDWVI
                     VRRAGDVIPEVVAPVLERRSGEPPRFVLLERFPTCPVCGSHVVRGEDEAVARCTGGLF
                     CPAQRKQALLHFAGRRAMDIEGLGDKLVDQLVDAAIVKTPVDLYRLGVLALANLERMG
                     EKSAQNLLMAIEKSRSTTLARFIFALGIRNVGEATARDLARHFGNLDALVAADVDALQ
                     QVPDVGPIVAQCIADFFGEPHNREVIEQLRAAGVQWAEGEPQGTVAGALAGKTFVLTG
                     TLPTLSRDEAKALIEARGGKVAGSVSKKTHYVIAGAEAGSKLDKAQALGLAILDEDGL
                     RALLNETDTNA"
     gene            33160..34062
                     /gene="galU"
                     /locus_tag="P5537_06070"
     CDS             33160..34062
                     /gene="galU"
                     /locus_tag="P5537_06070"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HRV77645.1"
                     /translation="MKKVTKAIFPVAGMGTRFLPATKASPKEMLPIVDKPLIQYAVEE
                     AVAAGITDMIFITGRTKRSIEDHFDKAYELETELEARGKKELLEIVRKTVPKGVNCIY
                     IRQSEALGLGHAVQCASHVVSDEAFAVILADDLLDNKDGTSVLKQMVDVYNYHRCSVL
                     GTMNVPREETRSYGIVSTESDKGQVQRMTGIVEKPKPEEAPTTQAVVGRYILTPRIFD
                     HIRALKPGAGGEYQLTDAIASLLKEEAVLAYQFNGVRYDCGSKLGYLKATIEFGLRHP
                     ETGPEFAQYLSGRFGAEPSVAKKK"
     gene            complement(34308..>34498)
                     /locus_tag="P5537_06075"
     CDS             complement(34308..>34498)
                     /locus_tag="P5537_06075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77646.1"
                     /translation="QAPSAPISVPPGDGGLIKIETDPAKRGQFGSGAVEQLVRLGRKP
                     RAVAVVVDEPLQQVETRK"
BASE COUNT         5377 a        11572 c        12453 g         5096 t
ORIGIN      
        1 ataaggtggt cgcggcgatg cggctggttt tctgtaggag cgccggcagg cgcgaacggg
       61 cggcggtcca tgcgccgccg ctctcttcgt cgccggattc gcgccttccg gagctcctgc
      121 atggggtggt cgcggcgacg cggtgggcgc tcctgcaaag ggggggggga gatcagcgct
      181 tcttgctgcg cttggcggat cgcttctcgc ccgggcgcgc cttggtcttg ggcgacttga
      241 ggcggggttc gccgctgcgg gccttgctgg tgttgagctt gaggccgggc tggcgggcgg
      301 cggtggcggc gagcgggagc aggctggtca cctcgagcgc gccgtccgga tcgatgccgt
      361 cgggcaccag cagcgaatag ccttcgcccg gccggctgcc ggggccgagg ccgttgagct
      421 tgcgcagctc ggccgagctt agcccgtggc gggcggcgac cgcctcgagg gtctcgcccg
      481 cggccatcac gtgcatccgc cattcgccgt cgtcctcgtc gagctcggcg agaccttgct
      541 gcagctgctc ggcgcggtcg gtagggacga tgaagatctg ccccggtgtg gtcaccgccg
      601 ggcggttgaa gctcgggttg agggcgagga actcgtccag cggcatgccg gagagcttcg
      661 ccgcggtagc gaggtccacg ccgatgggcg cctcgacgct gacgaagtgc agctcgttgg
      721 cgacataggg cagctcgaag tggaagagct cgggctcgga gacgatgttc ttgatcgcct
      781 gcagcttggg cacgtagttg cgcgtctcgt cgggcatgcg caggtgctcg tattcgagcg
      841 gcaggccgtc ctcggcgttg cgcttgagcg cgcgctgcac cgcgccttcg ccccagttgt
      901 aggacgcgag cgcaaggtgc cagtcgccgt gcatctcgta gatgcgctgc aggtagtcga
      961 gcgcggcgtt ggtcgaggcg atcacgtcgc ggcgctcgtc cacccagtgg tcctgggtga
     1021 ggttgtagtg cttgccggtg gaggggatga actgccacag gccggaggcg tgcgcgcgcg
     1081 agtaggccat cgggttgtag ctgctctcga ccatcggcag caaggcgatc tcggtgggca
     1141 tgccgcggcg ctcgagttcg tcgacgatgt agtagaggta gcgcccgccg cgctcgaaga
     1201 cctgcttgag gaagcgcggg cggttgaggt agaagctctg ctggtccatc acgcgctggc
     1261 tgtcgaggtc gggcatgccg aagccgcggc ggatgcggtc ccagatgtcg tgggcgtcgc
     1321 gagtgaggtc gagcgtaagc acccgcgccg tctcgggcgc gggcatcgcg gccagcgtgc
     1381 cttcagccgc gtcgccgatc cgcagcgagg tggccggaag cggggcagga gcgttgtcct
     1441 ggcctgccac gggtggggcg agaacggcca gggcgagggc gcaggcggcc agcaacgggc
     1501 cgcgcctgcg gctgccgcgg gcaatggcgg cacgaagatc ggaggaagtc atcggggctc
     1561 agaagcggtc cttccaggca cgcagcgccg cgaggcactc gagcgcatcc tgcgggcggc
     1621 tgccggcctg ggcggcgacg gcctcgatca ccccgggctg ctcgcagcgc aggaaggggt
     1681 tgatcgcccg ctcgcgggcg atggtgctcg gcagggtggg ttcgccgcgg gcgcgcaggg
     1741 cctcgcagtg cgcggcccag gcatcgcgtt cggcgttgtc gggctcggcc gcgcgggcga
     1801 aggccaggtt ggacagcgtg tattcgtggg tgcaatacac ccgggtgtcg gggggcaggg
     1861 cggccaggcg ggcgagcgag cgcccgagct gggccggcgt gccttcgaag agccggccgc
     1921 agccggcgga aaagagcgta tccccgcaga acaccaggcc gggctcgatg tccatgccca
     1981 cgtaggccac gtggccggcg gtgtgcccgg gcacgtcgag cacgcgcagc gtgagggcgg
     2041 gtgcgggcag gtggatctcg tcgccgtcgg cgacggcatg gacgacaccc gcgatcgact
     2101 cgcgcgcggg gccgtacacc ggtacacgat ggctcgccac cagcgcgccg atgccgccgg
     2161 tgtggtcggg atggtggtgg gtgaccagga tcgcggtgag cgtgaggccg tgctcgcgca
     2221 gggcttcctc gaccggggtc gcgtcgcccg gatcgaccac cagggcatgg cggccgtcgt
     2281 ggacgagcca gatatagtta tcgcggaagg cgggaatagg gataatgtcc atcccgcgaa
     2341 ttgtgaggac ctgagtgccg atgtcaatcc tccggctcga ggaatggctg cagaccccgc
     2401 aggggcgcta cctgctcgac tgggagcagg atgggctgga ccgcctggtg gcggacatct
     2461 tcggctatca cgcggtgcag ctcggcctgc ccgggttgga gttgctgcgc gccaatcgca
     2521 tgccgcgccg gatcaactgc ggcccgcaag gccgcgacct gtgctgcagc gaatacgagc
     2581 tgcccttcgc caccggcagc ctcgacttgg tgctgctgcc gcacgtgctc gagttttccg
     2641 cgcacccgca tcgggtgctg cgcgaggtcg agcgcgtact ggtgcccgag ggcagcgtgg
     2701 tgatcagcgg cctcaacccg atcagccttt ggggcttgcg ccgcctggtg gcgcgccgcg
     2761 gtgccgaggc gccgtggagc gggcactacc gctcggcgat gcgcatccgc gactggctca
     2821 ccctgctcgg cttcgagatc caggagagcc gcttcggctg ctacgccccg cccttgcgca
     2881 ctccgcgatg gctggagcgc tggcgctgca tcgaccgcgc cggctcgcgc tggtggccgg
     2941 tgctgggggc gggctacctg ctgcacggga tcaagcgggt gcagggcatg cggctgatca
     3001 ccccccactg gcgcggccgc aaggccgtgg ccaaacgact ttcgccggtc gcccagcgcg
     3061 acggctcgac gaggaacatg cagtagcgat ggaagaagtg gatatctata ccgacggcgc
     3121 ctgcagcggc aatccgggac ccgggggctg gggcgcgatc ctgcgttccg gcgcgcacga
     3181 gaaggagatc tggggcggcg agccggcgac gaccaacaac cgcatggagc tgctcgcggt
     3241 gatccgcgcc ctcgaggcgc tcaagcgccc ggtggcggcg cgggtgcaca ccgacagcca
     3301 gtacgtgcag aagggaatct cggagtggat ccacggctgg aaggcgcgtg gctggaagac
     3361 ggcctcgaag gagccggtga agaacgccga cctgtggcgg gcgctcgacg aggcggcgtc
     3421 gcgccaccag gtgaagtggc tgtgggtgcg cggccataac ggccaccccg agaacgaacg
     3481 cgccgacgcg ctcgcgcgcc gcggcgtgga tgcggtgcgc aagtccggcg ccgtggtgga
     3541 atgctgagga gctgccggca atgagacaga tcgtcctcga caccgaaacc accggcctcg
     3601 actggcgcaa cggcgaccgt gtcatcgaga tcggctgcgt cgagctgctc gaccgcggcc
     3661 ttaccggccg ccactaccac gtgtacatca accccgggcg cggcatcgac gccgaggcgg
     3721 tggcggtgca cggcatcacc gaggagttcc tcgccgacaa gccgaagttc tccgatatcg
     3781 tcgccgactt cgaggacttc gtgcgcgacg ccgagctggt gatccacaac gcgagcttcg
     3841 acgtcggctt cctggacgcc gagctcgacc gcctcgggcg cgccaggctg ggcgtgctgt
     3901 gtgccggggt catcgacacg ctcaagctcg ccaaggagca gaacccgggc aagaaggcct
     3961 cgctcgacgc cctgtgcgac cgctacgaga tcgacaacgc gcaccgcgag ctgcacggcg
     4021 cgctgctcga cgcggagctg ctcgccgagg tcttcctggc aatgacgcgc ggccaggaga
     4081 gcctgatgat cgggctcgac gacgagccct cggcgcgcga ggccgacagc gaaggcgccc
     4141 ccctgttgcg cgccgcgatt ccggttctgc gcgcgagcgc ggaggaatgc accgcccatg
     4201 acgcggtgct cgcggagatc gcgaaggcga acaaggggct gtgcctttgg ttgccgccag
     4261 agggggatcc ggcgcaggcg ggctgaggca tgcatccgcg gcgggggccg ccagggggcg
     4321 accctggcga tcgccgcgca ggccgggcat cgaaggctgc actccgcctt cgcacccggc
     4381 gagacgtgca gcggtgactt tcagcgctcg tcgcggcgaa ccttctcgag acccttgagg
     4441 atgtcgtggc gggagagctg gccgatcagg cgcgagccct cgaccaccgg caggctgcgg
     4501 tagttcttgg acaggaaaag ctcgatcgcg tcgatcaggc tcgcgctcgc cgagatcgac
     4561 gtgacgtcgc ggctcatgaa gtcttccacc gtgccctcgt cgcgacggaa atacgaggcg
     4621 tcgagcgccg ccttgaggca gtccttctcg gacaggaagc cgaccaggcg ctggttctcg
     4681 tcgacgaccg gcgcaccgct gaggccgcgc ttgaggagga gatgaaccgc cttgagcagg
     4741 tcggtattgg gcgaaaaggc gaggtgatcg ccgaccatgt agtccttgac gagcagcgaa
     4801 ccgagcatca tgtctcccgg gaatcagtgt tgttgttcgg cctgcgccgc cagcgcgcgg
     4861 gcctggcgct tcgagcacgg cttcttgcag ccgaactcgc agtcctggcc catcgcgccg
     4921 agcccgccgc agcttccggc gatcggcttg cggccgaaga ggacgccgat cgccatcgcc
     4981 aggatcacga ggccgacgac gagcagggtg atcaggaaag tgttcatcgt ttccaaccta
     5041 tcgggttgcg gatgttcagg catccgaacg tgtggacaat aacgcgggcc ggcgggttct
     5101 ggccatgggg gcgtgcgccc tggatccagc actgccagct cggccgcgcc tcacatgcgt
     5161 aacacgccgc cgggcaagct gcccgcgacc tccaggcgag tcaccgtggg cagcaggtcg
     5221 aggccggtct cggtcttcag ctggcgggca cgctcgcgca gttcctcgac ggcgcgctcg
     5281 atcggctcgc ccgccgcgcc gaaggcgacg acgttgccgc tgtcacagga cgggaaggcg
     5341 agcgcgcggt cttcgtaggc gcgcacgatg cgctccaggc tggccttgta gccgcgcgag
     5401 cggccgaaga ggttcaccgc catgatcccg cgcgccgaca gccgcgcgcg caccgcctga
     5461 tggaagggct cggtgtcgag cacgccggcg cgggcgttgc ggtcgaagcc gtcgaccagc
     5521 acgtagtccc attcctcatc gtgctcgagc acgaactgcg caccgcagcc gatatgcacc
     5581 gagaagcgcg cgtcctccgt cggcagcttg aagaactggc gcgcggcggc gaccaccgcg
     5641 ggcgcgatct cgaccacgcg gatcctggcc tgcggcaggt ggtgatgcac gaagcgcgcc
     5701 agagaggccg cgcccaggcc gatgatcagc accttgcgcg gccagtgcgc gccgtcggcg
     5761 gcgagaccgt cgcgcagcag caggccggcc atcatctcgc gggtgtaggc gagctcgagg
     5821 gcgtagggct tgcggatgcg catcgcaccc tggatccagt cggagccgaa gtgcaggtag
     5881 cgcacgccgg cttcttcgga gatgtcgatg gggagattca tggggtggga ggcgtcaggg
     5941 gtgaggtatg aggagcggtg ggtgcggggg gctcgcggtg gtgtcgggcg ctggggggcc
     6001 ggttaggggc tgggggatga tccggagtgc gccgctcagc cggcggccag gcgcttgagg
     6061 gcgtacaggc gttcgagcgc ctcgcgcggg gtgagcgcgt cggggtcgat gtcggcgagc
     6121 tcggtgagca ccgggtgcga cagcggtgcg tcctccggtt cgggcaggtc ggcgaagagg
     6181 tcggcctgcg ggccggcgtc gatctcgcgg ttctccagcg cgcgcagccg gcgcttggcg
     6241 tcgcggatca ccgtggccgg gatgccggcg agggcggcga cctcgatgcc gtagctctgg
     6301 ctcgccgggc cttcctccag cgcgtgcagg aagacgatgc ggtggccgtg ctcgaccgca
     6361 tccaggtgca cgttggcgca ctcggggtag tcggcgttga gccgggtgag ctcgaagtag
     6421 tgggtggcga acagcgtcag cgcgcgcgac ttctccagca ggtggcgggc gatcgcgaag
     6481 gcgagcgcga ggccgtcgaa ggtcgaggtg ccgcggccga tctcgtccat cagcaccagg
     6541 ctgcgctcgg tggcgccgtg caggatggcg gcggcctcgg tcatctcgac catgaaggtc
     6601 gagcgccccg aggcgaggtc gtccgaggcg ccgatgcggg tgaagatggc gtccaggggc
     6661 ccgagctcgg cggcgtccgc cggcacgaag ctgccgacgt gggcgagcag gcagatcagc
     6721 gccacctggc gcatgaaggt cgatttgccg cccatgttgg gaccggtgat catcagcatg
     6781 cggcgggtgg cggccaggcg cgcgtcgttg cggatgaagc tttcgacctg gcgctcgacc
     6841 accggatggc ggccgccgac gatgttcaag cctggggtgt cgacgaagcg cggctgcacg
     6901 tagccgtagc gcagcgcggc ctcggccagc gcggcgaggc cgtcgagcag ggcgagcgca
     6961 cgcgcgatgc gctgcaaagt cgggatgtgc gcggcgagca cgtccagcac ctggtcgaag
     7021 agcagcttct cgcgtgccag cgcgcgctcg ttggccgaca gcgccttgtc ctcgaaggcc
     7081 ttgagctcgg gcgtgatgta gcgctcggcg ttcttcagcg tctggcggcg gcggtagtcg
     7141 tcgggcacct tgtcggcgtt ggcgcggctg acctcgatgt agaagccgtg caccttgttg
     7201 aactcgacct tgagcccggg aatgccgctg cgctcgcgct cgcgggtctc cagcgccatc
     7261 aggaactcgc cgcagttggt ctggatgccg cgcagctcgt cgagctcggc atcgaagccg
     7321 ggggcgatca cgccgccatc gcgcaccatg gcggcgggct cggcggcgat ggcgtgctgc
     7381 agcagcgcga gcggctcggg ggcgatggcg agcgcgccga cgatctcggc gagcagcggc
     7441 gcgcggcaag gggcgagcgc ggcggcgagc tcgggcagcc gcagcaggct ctcgcgcagc
     7501 gccgagaggt cgcgcgggcg cgcgctgcgc agcgcgatgc gggcggtgat gcggtcgacg
     7561 tcggccacgc cacgcagcgc gccgcgcact gcgaaggcga cgcggccgtc gcggccggcc
     7621 agcgccaggc cggcggcgcc ggcgccctgc gccactgcgc cgccccctgt accgcccgcc
     7681 tcgacgttca tgtccgcttc ggccgcaccc accagctcgg ccaccgcggc atggcgcgcg
     7741 gcgggctcgg cgcgctcgcg cagcgggtgg tgcagggcat ggcgcagcca gcgcgagccc
     7801 atgctggtca cgcaggtgtc gagcagcgac agcagggtcg gcgaggactc gccgcgcagg
     7861 gtctcggtga gttccaggtt gcgccgggtg gcggcgtcca ggcgcagggt ttcggattcg
     7921 cgctcgacga cgaggccggt gacgtgggcg agcgtctggc gctgggtggc ctgggcgtag
     7981 tcgtacaggg ccgcggcggc gccgagcgcc accggcaggt cctcgacgcc gaagccggcg
     8041 aggtcgcggg tgccgaagtg ggtggtgagc aggcgcgtgc cggtctcggc atcgaactgc
     8101 cagtcggcca gccggcgctg cgcgggggcg agcgcgtcga ggagcggcag ggcgaggccg
     8161 tcgggcacca gcacttcggc cgggcgcagg cgctcgaact gcgcctgcag cgcatccgac
     8221 gggcactgca tgaggcggaa gtcgccgttc gcgaggttca gccacgctag cccgagcacg
     8281 ccgcggtgca ggctggcggc gagcagcagg gaatcgcggc ggtcgtcgag cagcgcggcg
     8341 tcggtcagcg tgccgggggt gacgatgcgg ctcaccgcgc gctccatcgg ccccttggtc
     8401 gcgcccggct cgcccacctg ctcggcgatc accaccgatt cgccgagttt gaccaggcgg
     8461 gcgaggtatt gctcgaccgc gtggaagggc acgcccgcca tgcggatcgg cttgccgccc
     8521 gactggccgc gggtggtgag cgtgatgtcg agcaggcgcg cggccttctc ggcgtcgtcg
     8581 aagaagagct cgtagaagtc gcccatgcgg tagaagagca gggtgtccgg atgctgctgc
     8641 ttgatccgga ggtactgctg catcattggc gtgtgggcgc cgatctcggc ctcgctcagg
     8701 gcggcggggc ggatggcggt gtcgtcgaag ggcggcttgc ggattgccaa ttgaagaaac
     8761 ctcccggttg ccgtgctgtc gtcagcatag gcaggattat caccgtggat cgaaggaagg
     8821 accgacttga acaccccgga cgccgacacc cgccgcatcg gccgcaggct gggcctgctg
     8881 gcgacgctcg cctttctcgc gctgggctgg gtgagcttcg acggcgcgat cgagcgccgc
     8941 gaggacccca accgcaatct cgtggtcgcc cccggcgcca gcgagctggt gctgcagcgc
     9001 aaccgcgccg ggcactacct gctgccgggc gagatcaacg gccgtccggt gcgcctgctg
     9061 ctcgacaccg gcgccacaca ggtgtcggtg cccgcgcgcc tcgccgcgga actgggactg
     9121 caggcgggcg cgccggcgtc ggtgcggacc gccaacggcg cggtgacggt gcgccagacg
     9181 cgcattccgc gcctcgcctt cggccccttc gagttccgcg acgtggccgg tcacctcaac
     9241 ccgggcatgc agggcgacga ggtgctgctc ggcatgtctg ctttgcgtca cctggagttc
     9301 acccagcgcg gcgatacgct gaccctgcgc gcgccgggtt ctccgggggc gtcctgagcg
     9361 gcggtcctca ggcctgcaga ttggccgggc gccaggcctg gatgatcggc agcagctggc
     9421 cgaagatctt cggcgagccc gcgacgaggt tgccggtggc gaggtagttg gcctcgcccg
     9481 agaggtcgga caccaggccg ccggcctcct ggatcagcag tacgcctgcc gccatgtccc
     9541 acggcgacag acccatctcc cagaagccgt cgaagcggcc cgcggccacg taggcgaggt
     9601 cgagcgaggc ggcgcccggg cggcggatgc cggcggtctt ctgggtgagc tccttgaaca
     9661 ttgccaggta ggcgtcgacg tggtcgaact ggcggaaggg aaaaccggtc ccgatcagcg
     9721 actcgttgag gcgggtgcgg cgcgagacgc ggatgcggcg gtcgttgagg aaggcaccgg
     9781 cgccgcgcga ggcggtgaac atctcgttgg tgttgggatc gtagaccacc gcgtgctcga
     9841 gcacgccgtt cttggtctgc gcgatcgaga ccgcgtactg cggcatgcca tggatgaagt
     9901 tggtggtgcc gtcgagcgga tcgatgatcc aggtgaactc gctctccggt ccggactcgc
     9961 cggactcctc tgctagaatc ccgtgccccg ggaaggcgtc gcgcagcacc tcgatgatcg
    10021 cctgctcggc ggcgcggtcg acctcggtga cgaagtcgtt gggcgacttg gactgcacgg
    10081 tcagcagatc gagctgggtc gacgcgcggt tgatgacggt cgcggcgcga cgggcggcct
    10141 tgacggcgat gttcagggtg ggatgcatgc ggagcggtct cggttaaaga atcggggcct
    10201 gccacgtgcg ccgggtgcgc gccgccgccc gcttcatcga gccgccgcgc ggccctcggg
    10261 ccacgttccg ggcaggcagc ccggcaaatt cggaaaacgc ggaattttaa tatgaatcgc
    10321 ccccttgcgc tcgaccgcat ccgcgtcgtg ctgtcccgta ccagccaccc cggcaacatc
    10381 ggcgccgctg cgcgcgcgat gaagaccatg ggcctgcgcg agctctggct ggtcgcgccg
    10441 gagtcctttc ccgacgaggt cgccagcgcg cgcgcctcgg gtgcggccga cctgctggag
    10501 aaggcgcgcg tggtcgacac cctggaggag gcgctcgccg acacggtttt ctcggcggcg
    10561 ctcaccgcgc gtcggcgcga gctatcgctg ccgcgcctgc aggcgcgcga cgcggcggtg
    10621 gagctggtgg ggcgcacgca ggacggcgcg gtggcgctgg tgttcggcaa cgagaccagc
    10681 gggctcacca acgaggaagc cgccctgtgc agccttcccg tgaccatccc caccgacgcg
    10741 gagttctcgt cgctgaacct cggcgcggcg gtgcaggtgc tggcctacga gttgcgcatg
    10801 gccgcgctcg gcgatgctgc cgcgcctgcc gacccgcagc ccgagccggc cacccatgcc
    10861 gacttcgagg gcttcatggc ccacctcgag cgcgccgtca ccgccagtgg ctttcatgac
    10921 cccgccaacc ccaagcgcct gctgccgcgc atgcggcgcc tgttcaaccg cgtgcggctc
    10981 gagcgcgagg aggtcgccct gctgcgcggc atgctcacca ccttcgagac cccccgccgc
    11041 cgcggctgat cgctgcacac tgcgcggacg atcttgcggg ggttcttgta ggagcgccgg
    11101 caggcgcgaa gaccacgcca gggatgcccc ccgcgtcgat tgcgcgaccg cccggctcgc
    11161 ggcttgcgcc gcccctgcag acgtccggaa gcacggcggt ttctgtagga gcgccggcag
    11221 gcgcgaacaa ggccgcgggg gaagggacgc gcgtcgggtg accgtgcgcc gctttcgcgc
    11281 ctgccggcgc tcctacagaa accggcgcgg gtcggaagct tttgtaggag caccggcagg
    11341 ggcgaacgcg gctgcgcgca aggcgcgggc tttcgggggt gcggtatagt cgattaaaat
    11401 gatcgggaat tggtgtcccg cccgcttggg cggtgccgct ccgctttctt gtttctgcgc
    11461 acacccggga gtcccttcat catgttcagc cgcctccgag aagacctggc cagcgtccgc
    11521 gagcgcgacc ccgccgcgcg ctccacgctc gaggtgctga cctgttaccc cggcatccac
    11581 gcgctgatgt tccatcgcct cgcccacggc gcctggcgcc gcggctggtt ttgggcgggg
    11641 cgcttcgcca gccacatcgg ccgcctgctt accgggatcg agatccaccc cggtgccagg
    11701 atcggccgcc gcgtgttcat cgaccacggc atgggcgtgg tgatcggcga gaccgcggag
    11761 atcggcgacg actgcacgat ctaccagggg gtcacgctcg gcggcacctc gctctaccgc
    11821 ggcaccaagc gccaccccac cttggggcgc ggcgtggtgg tgggcgcggg cgcgaaggtg
    11881 ctcggcggct tcacggtggg cgacggcgcc aaggtcggct ccaacgcggt ggtggtcaag
    11941 ccggtgcccg ccggcgccac cgcggtgggc aaccccgccc gcatcctcga ttccgagcgc
    12001 gatgccgcgc gcgagcagaa ggccgagcag atcggcttca gcgcctacgg cgtgacccgc
    12061 gacatggacg acccggtcgc caaggcgctg cacggactgc tcgaccattc ggtggagacc
    12121 gaccgccgtc tgcaggccat cctcgcgcgc ctcgaggccg ccgggatcaa gctcgacgac
    12181 accgtggcgc cgaacgacga tttcgacccg gggcgcctgt cgcggatggt ggattgagca
    12241 gcacgcgccc tccgcgtcga tggaccgacg gccgctttcg cgcctgccgg cgctcctaca
    12301 agtgctcccg acccgcgccg gttcctgtag gagcgccggc aggcgcgaaa gcggcgctcg
    12361 gccacccgac gcgcatccct tcccccgcgg cccattcgcg cctgccggcg cacctccaag
    12421 tgctcgcgac ccgcgccggc ttctgtaggc gccggcaggc gcgagagcag cgcacggggt
    12481 cggcctacct ccatctctgc gctgctttgg cgccgcgcct gcaagggcgc accttcatcc
    12541 tcgattagtt gaccgttttt gtcgggatcc atatactcga ccaaaatgat gggatattcg
    12601 gcggcccacg gcacgcgcga gcccggacag ccttcgagga gagcctcatg cgacttacga
    12661 ccaagggacg gtttgcggtg accgcgatga tcgacctggc tgcacgccag ggggatggcc
    12721 ctgtcacgct ggcgggcatc gccgagcgcc agagcatttc gctgtcctac ctcgagcagc
    12781 tcttcggcaa gctgcgcagg cacaagctgg tcaacagcgt gcgcggcccc ggcggcggct
    12841 accgtctggc gcgagcgatg gacgagatca ccgtcgccga catcatcatc gcggtcgacg
    12901 agccgatgga cgccacccag tgcggcggca aggagaactg ccacgacgac cacgtgtgca
    12961 tgacccacca cctgtggtcc aacctcaacc agcgcatcta cgcctacctc gactcggtga
    13021 gcctggaggc gctggtcaag catcaggtgc ggcccgaccc cgacatgacg gtgctcaaga
    13081 gcgtgcgccg gcgcagccgc atgccggtgc acgagatcgc cgccgtctga cccgaggcgc
    13141 gcatgagctt cacccccgcc tacctcgact ggaacgcgac cacgccgctc gacccggccg
    13201 tgcgcgaggc catgctgccc tggctcggcg cggccgagcc ggtgcgcttc ggcaacgcct
    13261 cgagccgcca cgagtacggc cgccaggcgc gtgcggcggt ggacgaggcg cgcacacggg
    13321 tggcggaagc ggtcggcgcg cacgcgaccg aggtgatctt caccagcggc ggttcggagg
    13381 ccaacaacct cttcctcaag ggcgccgcgc ccaacctcaa gccgggcgtg gtcgcggtga
    13441 gcgcgatcga gcatccgtgc gtgcgcgagc ccgcccgcca gttgcggcgc gcgggctgga
    13501 cgctgcgcga gatcggcgtg gacgatcagg gccggatcga cctcgcggac tgggctgcgg
    13561 tgctcgaatc ccgccccggc ctggtgtcgg tgatgctggc caacaacgag accggcgtcc
    13621 tgcaggacgt ggccgcgctg gcgcgcgagg cgcgcaccag cggcgcctgg ttccacaccg
    13681 acgcggtgca ggggctgggg aaggtggcgg tggatttccg cgcgctcggc gtgaacgcga
    13741 tgacgctgtc ggcgcacaag atcggcgggc cgctcggcgc gggcgcgctg gtggtggaca
    13801 agcgcgtcga gctggcgccg ctgatcgccg gtggcgggca ggagcgcggg ctgcgctcgg
    13861 gcaccgaaaa cgtcgccgcg atcgtcggct tcggcgtggc ctgcacgcgc gcggtggcgc
    13921 ggcgcgaagc cgaggccgtg cgcctggccg cactgcgcga cgaactttgc gctgcgctcg
    13981 ccgggcgcgg cgcgaggatc ttctcggtgg ctgccccgcg cctgccgaat accgtattct
    14041 tcgccgtcga ggacatcgac ggcgagaccc tggtcggccg cctggaccga gccgggtttg
    14101 cctgcgcgag cggctcggcg tgctcgagcg cgaaccccga gccgtcccac accctgctgg
    14161 cgatgggcgt ggagcccggg ctggcgcgcg ccgcggtgcg cgtaagcctc ggccgcgaca
    14221 cgcgcgcgga cgacgtgcat agcttcatcg aaaccttcgt ccgagtgacg gacgagctca
    14281 agagcctggc ctcgatcggg gcctgaaccg gccacgctgg ccatccaccg aactcgctaa
    14341 cgaagaaagt gcggagagac acaatgctga agttccccat ctacctcgac tactcggcga
    14401 cgaccccggt cgatccgcgc gtggcggcaa agatgatccc ctggctgacc gagcacttcg
    14461 gcaacccggc gagccgctcg cacgcctacg gctgggaggc cgagaaggcc gtcgaggatg
    14521 cgcgcgaaca ggtcgccgcg ctggtcaatg ccgacgccaa ggagatcatc tggacctcgg
    14581 gcgcgaccga atcgaacaac cttgccatca agggtgcggc gcacttctac cagggcaagg
    14641 gcaagcacat catcacggtg aagaccgagc acaaggccgt gctcgacacg gtgcgcgagc
    14701 tcgagcgcga gggcttcgag gcgacctatc tcgacgtgca ggagaacggc ctgatcgacc
    14761 tcgaggtgct caaggcggcg atccgacccg acaccatcgt ggtgtcggtg atgttcgtga
    14821 ataacgagat cggcgtcgtc cagccgatcg ccgagatcgg cgagctctgt cgcgagaagg
    14881 gcgtggtctt ccacgtcgac gctgcgcaag ccaccggcaa ggtcgacatc gacctcgaca
    14941 agctcaaggt cgacctgatg agcttctgtg cgcacaagac ctatggcccg aagggcatcg
    15001 gcgcgctcta cgtgcgccgc aagccgcgcg tccgcctcga ggcgcagatg cacggcggcg
    15061 gccacgagcg cggcctgcgc tcgggcacgc tggccaccca ccagatcgtc ggcatgggcg
    15121 agtccttccg tctcgcccgc gaggagatgg ccgaggagaa cgcccgcgtc ggcaagctgc
    15181 gcgaccgcct cctcgccggc ctcaccgacc tcgaggccac ctatgtgaac ggcgacctcg
    15241 agcagcgcgt gccgcacaac ctcaacatct ccttcgccta cgtcgagggc gagtcgctga
    15301 tcatggcggt caaggacatc gcggtctcct ccggctcggc ctgtacttcc gccagcctgg
    15361 agccgtccta cgtgctgcgc gcgctcggcc gcaacgacga actcgcgcac agctcgatcc
    15421 gcttcaccat cggccgcttc accaccgagg aagagatcga atacacgatc aagctcctgc
    15481 acgacaagat cggcaagctg cgcgagctgt cgccgctgtg ggagatgtac aaggacggcg
    15541 tcgatctcga cgcggtgcag tgggctgccc actgaacttt agtgcagaag atgatgtaaa
    15601 ttgcaggtga agcgattcac cgccccagca ggagaaaaaa catggcatac agcgaaaagg
    15661 tcctcgacca ctacgaaaac ccccgcaacg tcggctcctt cggcaaggaa gaggacggcg
    15721 tcgccaccgg catggtcggc gcgcctgcct gtggcgacgt gatgaagctc cagatcaagg
    15781 tcggcaagga cggcgtgatc gaggacgcga agttcaagac ctacggctgc ggctcggcga
    15841 tcgcgtcgag ctcgctggtc accgagtggg tcaagggcaa gaccctcgac caggcgctcg
    15901 agatcaagaa cacgcagatc gccgaggaac tcgcgctgcc gccggtgaag atccattgct
    15961 cgatcctggc cgaagatgcg atcaaggccg ccgtggcgga ctataaaaag aagcatgagg
    16021 cctgagcggc cttcgtcgaa gaggaggaaa catggctgtc acgctttctg aatcggctgc
    16081 gcgccacgtc tcgaacttca tcgccaagcg cggcaagggc ttcggcattc gcctcggcgt
    16141 gaagacctcg ggctgttcgg gcatggccta caagctcgag ttcgtcgatc agacggagga
    16201 cgaggacgag gtcttcgaga gccacggcgt caaggtcgtc atcgacccca agagcctggc
    16261 ctatctcgac ggcaccgagc tcgacttcgt caaggaaggt ctcaacgagg gcttcaagtt
    16321 caacaacccg aacgtcaagg accagtgcgg gtgcggcgag agcttcaacg tctgagccgc
    16381 gcccgatgag catcgacctg acgcaggact acttcgcgct cttcggcctg ccgcgccgct
    16441 atgcgctcga cgaaggcgcg ctcgaagccg cctggcacga gctgcagggg cgcgtgcatc
    16501 ccgaccgaca cgcccacctc tccgacttcg agaagcgacg ctccatgcag tgggcgacgc
    16561 gggtcaatga aggctttcgc gtgctgcgca agccgctcgc gcgtgcccag tacctgctcg
    16621 agctcgccgg ggtcgatgcc gcgctcgaga ccaacaccgc gatgtccgcc gagttcctga
    16681 tggaacagat ggagtggcgc gaggcggtgg aggaggcgcg cgaggccgcc gaggtctcgg
    16741 agctcgagga cctgcaccgg cgtctgctcg ggcatgcgcg cgaggtgcgc ggtcacctcg
    16801 cggcgcagct cgacgagcac caggactacg aagccgcggc cgacaccgtg cgtcgactga
    16861 tgttcatcga caagctccag caggaaatcg acgaagcgct gctcgcgctc gaaaactaga
    16921 acgccagaaa ggcacggaac agcaccgatg gccctgttgc aaatcaccga acccggcatg
    16981 tccaccgagc cgcacaagca caggctcgcc gtcggcatcg acctcggcac caccaattcg
    17041 ctcgttgcca ccgtgcgcaa cggcatcgcg atctgcctgc ccgacgaggc cggccgcacc
    17101 atgttgccct cggcggtgcg ctatcaggcc gacggcggca tcgaggtcgg gctcggtgcg
    17161 ctcaaggcgc aggcggtcga cccgcgcaac accatcgtgt cggtgaagcg cttcatgggt
    17221 cgcggactca aggacgtcgc ccacatcgag gcgatgccct acgacttcga ggacagcccg
    17281 ggcatggtgc ggctgcgtac cgtccagggt gtcaagagcc cggtggaggt ctccgcggag
    17341 atcctgcgcc ggctgcgcga gcgcgcggag gccagcctcg gcggtgcgct ggtcggggcg
    17401 gtgatcaccg tgccggccta cttcgacgac gcccagcgcc aggccaccaa ggacgccgcg
    17461 cgcctggcgg gactcgacgt gctgcgtctt ctcaacgagc cgaccgccgc ggcggtggcc
    17521 tacggtctcg acaacgcggc cgagggcgta tacgcggtgt acgacctcgg cggcggcacc
    17581 ttcgacctct ccatcctcaa gctctcgcgc ggcgtgttcg aggtgctgtc gaccaacggc
    17641 gacgcggcgc tcggcggcga cgacttcgat caccgcctgt tctgctggat cctcgatcgc
    17701 gccaagatct cgccgccctc gctggaagac gcgcgccgcc tgcagatgaa ggcacgcgag
    17761 gccaaggagc tgctgacgag ctgcgacgag gcgccggttc atgtgcggct gggctcgggt
    17821 gaagaggtgg acctcgtggt gacgcgcgag gagttcgccg agatgaccac gcatctggtg
    17881 cagaagaccc tggcgccggt gcgcaaggcc ttgcgcgatg ccgggcttgc tcccgacgag
    17941 atcaagggcg ttgtgatggt gggcggcgcg acgcgcatgc cgcacgttca acgcgcggtg
    18001 gcgaactact tcggccagga gccactgacc aacctcgacc ccgacaaggt cgtcgcgctc
    18061 ggcgcggcga tgcaggccaa cgtgctcgcc ggcaaccgtg ccgaccagga cgactggctg
    18121 ctgctcgacg tgatcccgct ctcgctcggc ctcgagacca tggggggcct ggtcgagaag
    18181 gtcgtgccgc gcaactccac gctgccgatc gcgcgcgccc aggaattcac caccttcaag
    18241 gacggccaga ccgcgatggc cttccacgtc gtccagggcg agcgcgagct cgtctccgac
    18301 tgccgctcgc tggctcgctt cgagttgcgc ggcatcccgg ccatggtggc gggtgcggcg
    18361 cgtatccgcg tgaccttcca ggtcgacgcc gacggcctgc tgtcggtgtc ggcgcgtgaa
    18421 atgtcctcgg gcgtcgaggc cagcgtgctg gtcaagccct cgtacggact gtccgacgac
    18481 gagatcgccg agatgctgcg ctcgggcgtg gatcacgccg gcgacgacat ggccgcacgc
    18541 gcactgcgcg agcagcaggt cgaggccgac cgcgtcgtcg aggccaccga gcaggcgctc
    18601 gcgcacgacg gccatctgct ctcggcctcc gaagcggaag agatccgcag cgtcatcgcg
    18661 cgcctgcgcg agctgcgcgc gggcaacgac aaccgcgcga tcaaggcagg catcgacgcg
    18721 ctcgcgcgcg ccaccgacac cttcgccgcg cgccgcatgg acaacagcat ccgcagcgcg
    18781 ctggccggcc acaaggtcga cgaacttccc atctgaaact tcgcccatga cccagatcat
    18841 cgtccttccc catgtcgaac tctgtccgga cggcagcgtc ctcgaggccg cccccgggac
    18901 caccatctgc gacgcgctgc tcgacaacgg catcgacatc gaacatgcct gcgagaaatc
    18961 ctgtgcctgc accacctgcc acgtcatcgt gcgcgagggc ttttcctcgt tgaacagcgc
    19021 cgaggacgag gaggaggatc tgctcgacaa ggcctggggc ctggagccgc agtcgcgtct
    19081 gtcctgccag gcggtggttg ccagcactcc gctggtggtc gagattccgc gctacacgat
    19141 caacatggct cgcgaaggaa agcactgaca tgaagtggac cgaagttcag gagatcgcca
    19201 tccagctcac cgacgcgcac cccgacgtcg acccgacgcg ggtgaatttc gtcgacctga
    19261 tgaactgggt gatggccctg cccgatttcg acgacgaccc gaagcgctgc ggcgaacgca
    19321 tcctcgaagg catccagcag gcctggatcg acgaggtcgc ctgaggcccg agtttgcgcc
    19381 aaagaacccg tcgcgcagcg gccccccgta ggagctgcgg cagccgcgaa cagggccgtc
    19441 ggatatccgc cgcgcgtcgg gattttcgcc gccttgttcg cgcctgccgg cgctcctaca
    19501 tgaagcatcg cggaggctca atatgcgccg cgcgcgaccg tctccgtggt ctcgttgagc
    19561 tccagccagt agtgcccgat gagtccgatt gcacgctcga agcggtcgaa atccaccggc
    19621 ttgcggatgt agctgttggc tcccagacgg taggcctggg cgaggtcgag cggttcgcga
    19681 gaggtcgtca gtaccaccac cggtagaagc gcggtgcgct ggtcggcgcg gatgcggcgc
    19741 agcacctcca gcccgtcgat gcgcggcagc ttgagatcga gcagcaccac cgcgggcagc
    19801 ggcggcagcg tctgccccgc gcggctgccg gtcgagaaca ggtattccac cgcctcaacg
    19861 ccatcgtgcg ccaccaccac cgggctgctg atgcggttgc gcgaaagtgc gtgcaaggtc
    19921 agcgcctcgt cgtccgggtt gtcctcgacc agcaggatcg gtctctcgct tgccatgtgc
    19981 ctggatggat gaaggtagtg gtcgggacgc ggggaagcgt ttcagagatc ctcgcggtgc
    20041 agcaggaaga ccatgtcgtc gccaccacgg gtggacagcc actggaaggg caggtcgggg
    20101 aaggcagcct cgacgatgtc gcgattatgc ccgacctcga ccgccaggat gccgcccgga
    20161 ttgaggtgat cggcagcctc cgcgagcagg cggcgcacca cgtccaggcc gtcctcgccc
    20221 gaggcgagcg ccatctgcgg ctcatgcagg tattccggcg gcagcgcgtc catggcctcg
    20281 gcggtgacgt agggcggatt gctcaggatg aggtcgaagc ggcgcccttc gaggccctcg
    20341 aagacgtcgc cgtggaccag ttcgatgcga tcctgcagac cgtagtcggc cacgttgatg
    20401 cgcgcgacct cgagcgcatc ctccgacaga tcgaccgcgc acacctcggc gttggggaag
    20461 gcatgcgcca tcaggatcgc aaggcagccc gagccggtgc acaggtccag cgcgctgacc
    20521 accgcctccg gatcctccac ccagggcgcg aagccatcct cgagcaactc ggcgaagaag
    20581 gagcgcggaa cgatgacgcg cgaatcgacg gtgaagcgga agtcgcccag ccaggcctcg
    20641 ccgaggaggt aggcagtggg aatgcgctcg tcggcgcgtt gctcgatggc ttcgagcagg
    20701 gcgatacgct cctcggacgg aatgcaggcg tccatgaagg gctcgaggcg gtcgagcggc
    20761 agcgccaggg tgcccaggat gagccatacg gcttcgtcga agctgtcgtg cacgccatgg
    20821 ccgcagaaga tcccggcgcg gttgaagcgg gtgacggcgt agcggagcca gtcgcgcacc
    20881 gtgacgagct cggcgagcgg gccgtgctca tgttcgtgct cgtggtccgg gttctgctcg
    20941 agctcgtggt cgggggcgtc gtcgtgatgg gtttcaggca tggagagctc gtttcgtgga
    21001 tgggggcgtg caaaccgcgt cgcggtcgct tcgggcgtgg tgccgatcgt agcagtgtcc
    21061 gcgcagtcgg tcgcgatgat tcctgtagga gcgccggcag gcgcgaaggc tgcggtgggg
    21121 atcgtgacgg gctgcacttg tctgaacgcc ttgttcgcgg ctgccgccgc tcttacaagc
    21181 tggccgaggc gaggagggcg gccagggtgc gctggtacac cgccgacaag ggctcgatcg
    21241 cgtcggcagc gatatgttcg tcgatcttgt ggatggacgc gttgaccgga ccgaactcga
    21301 ccacctcggc gcagatctcg gcgatgaagc gaccgtcgga ggtgccgccg ctggtcgaca
    21361 gctcggtgtc gacgcccaac gtgtcgcgga tcgcggccga cagcgctccg accagcttgc
    21421 cgcggccggt gatgaagggc tttcccgaca ggtgccagtc gatctcgtat tcgagaccgt
    21481 ggcggtcgag cacctcgcag gtgcggcgct tgagctcgtc cgcgctcgac accgagccga
    21541 agcggaagtt gaacatcacc tcgcacacgc ccgggatcac gttgttggcg ccagtgccgg
    21601 cgtggatgtt cgacacctgc caggtcgtgg gcgggaagaa ctcgttgccc tggtcccact
    21661 cgatcgccgc gagctcggcg agcgccggcg cgaagaggtg gatcgggttg cgcgcgagct
    21721 gcgggtaggc aacgtggccc tgctggccct tgactcgcat cgtgcccgac agggagccgc
    21781 ggcgcccgtt cttgatcatg tcgccgaggg tcttcaccga ggtgggctca cccaccacgc
    21841 agtagtcgag gcgctcgccg cgcgcggcca gggcctcgac caccttgacc gtaccgtggg
    21901 tggcgatgcc ttcctcgtcc gaggtcagca gcagcgcgat gctgccggcg tgatcggggt
    21961 gggcggcgac gaagcgctcg atggcggtga cgaaggcggc gagcgagctc ttcatgtcgg
    22021 ccgcgccgcg gccgtagagc acgccgtcgc ggatcgtcgg gacgaagggc ggcgaggacc
    22081 acgcggcgtc cggcccgggc ggcacgacgt cggtgtggcc ggcgaagcac agcacggggg
    22141 ccgagtcgcc gcgccgcgcc cacaggttgc acacgccgcc ggtgtcgatg cgctcgatgc
    22201 ggaagccgag cggggcgagg cgcgaggcga ggagttcgag acagccggcg tcttcggggg
    22261 tgacggaggg gcgggcgatg agctcgcagg cgagcgcgag ggtgggggtg ctggagaggc
    22321 tggtctgcat gggggagggc gccgcggggc gggcctagtt gttgttgagg tccagggtga
    22381 attcctggaa ggaggcgccg tcggtgttgg tggcctcgaa accggtgatc gaggtgttgc
    22441 cattcacggt cagcatcggg tcgctctgca tctgcgcgtt gttgatcagc cagtgcaggt
    22501 tgctcggcga gtcggcgttg gcgagcgcct cgtcgagggt gatgatgttc tcgtggtgga
    22561 gccggtacag cgcctgctcg aaggtctgcg agccctgggc gagcgactgc tccatcgcct
    22621 ccttgatcgc gttgagctcg ccgcgctcga ccagctcggc gatgtggcgg gtgttcatga
    22681 ggatctcgac cgccgggatg cgcttgccgt cgggcttgcg cacgaggcgc tgggagatga
    22741 cgcagcgcag cgccaccgcg aggtcgaggt agagcagctg gcggttttcc agcgggaaga
    22801 agttaacgat gcggttgagc gcgtggtagg cgttgttggc gtgcagcgtg gcgaggcaca
    22861 agtggccggt ctgcgagtag gagatcgccg cctgcatggt ctcgcggtcg cggatctcgc
    22921 cgatcaggat gcagtcgggc gcctggcgca tggcgttgcg cagggcctcg ccccagctca
    22981 aggtgtcgat gcccacctcg cgctggttca ccaccgactt gcggtgcttg aagaggtatt
    23041 cgatcgggtc ctcgatggtg aggatgtggc cgctgcggtt gcggttgcga tgatcgatca
    23101 tggccgcgag cgtggtcgac ttgcccgagc cggtcgcgcc caccaccagc accaggccgc
    23161 gcttctcgag gacgatgtcg tcgagcaccg gcggcaggcc gagcgcgccg atgctcggga
    23221 tatcgctctg gatgtagcgc accaccaccg ccatcgagtt gcgctgccag aacacgttga
    23281 cgcggaagtt gccgaggtct cgccggccga aggacaggtt gagctcgcgt tcgcggtcga
    23341 gcaccgactg ctgggccggc gtgatggcct cgtggagcat gcgctggatc atcagcgggt
    23401 ccatgacctg ctggttgatc ggcatggtgt ggccctggat cttgatgtgg atcggggtgc
    23461 cggcggtgat gaagatgtcc gaggccttct tctcggccat caactggaag agattgtcga
    23521 agatcacgcc gtcggactcc tgtcgtcacc aaaaaataag ccgcccgcac gcagcgcaag
    23581 cgcacgcttg ctgcaaacgc cgctacgtct gcatcttcgc ggcgcccgcc tgtaggagcg
    23641 ccggcaggcg cgcatccggg cttgcaccac cggctaccgc ctccggcaca cgcatcgcgc
    23701 cggtcttcgc gcctgccggc gctcctacag gggcgtcggc ggttcgatgt tcgcgcctgc
    23761 cggcgctcct acaggggcgt ggcggttcta tgttcgcggc tgccggcgct cctgcagggg
    23821 tgatgcgtga aggttcatgt aggagcgccg gcaggcgcga attccgcccg ccccctcagg
    23881 cgccgcgcag cagctcgttg atgccggtct tggcgcgcgt ctgcgcgtcg acccgcttca
    23941 cgatcacggc gcagtacagg ctgtacttgc cgcaggccga gggcaggctg cccggtacca
    24001 cgacggcgcc ggccggtacg cggccgtagg tcacctcgcc ggtctcgcgg tcgtagatct
    24061 tggtgctcat gccgatgtac acgcccatcg acagcaccgc attctcctcg atgatcacgc
    24121 cctcgaccac ctccgagcgc gcgccaacga agacgttgtc ctcgatgatg accgggccgg
    24181 cctgcaccgg ctcgagcacg ccgccgatgc cgacgccacc cgacaggtgc acgttcttgc
    24241 cgatctgcgc gcacgaaccg accgtggccc aggtgtcgac catcgtgcct tcatccacat
    24301 aggcgccgat gttcacgtac gagggcatca gcaccacgtt cctgccgatg aagctgccct
    24361 tgcgcgccac cgccggcggc accacgcgga agccgccttc gcggaactgc tcgggggtgt
    24421 agtcgccgaa cttggtcgcc accttgtcga agaagttgag gccgccggcc tgcaccacct
    24481 cgttgtcgcg caggcggaag gagatcagca ccgccttctt gatccactgg ttgaccaccc
    24541 actggccgtc cttcttctcg gccacgcgca acgtgccggc gtccaggccg gcgatgacct
    24601 cttccaccgc gttgcggatc tcggcggggg cggcagcggg cgacaggctg gcgcggttct
    24661 cgaaggcggt gtcgatgatc gattgcagag cgtgcatgta gggattctct ctcagagggt
    24721 tttgcagaaa tcgatgatgc gcgcggcggc ctcgacacac tcgtgggtgt cggccaccag
    24781 ggcgatgcgc acgaaaccgg cgcccgggtt gacgccattg gcttcgcggg ccaggtagct
    24841 gcccggcagg accgtcacat tatattcagc ctgcagacgg cgggcgaact cggtgtccgg
    24901 gatcggcgtg cgcacccagt agtagaagcc ggcgtcgggc agcgacaccg gcagccaggg
    24961 ctgcagcatg ggggtgatgc gggcgaactt gtcgcggtag aggcggcggt tctcctcgac
    25021 gtgctcctcg tcgttccagg ccaccaccga ggccgcctgc accgccgggt tgagcgcgca
    25081 gccgtggtag gtgcggtaga gcaggaagtc cttcaggatc ctggcgtcgc cggcgacgaa
    25141 gcctgagcgc atgcccggca cgttcgagcg cttggacagg ctggagaaca tcaccacgtt
    25201 gcgaaaatcc gtgcgcccca ggcgccaggc cgcctccagg ccaccgatcg gcttgtcggc
    25261 gtcgtcgaag tagatctcgg aatagcactc gtcggctgcg atcacgaagc cgtagcggtc
    25321 cgacagctcg aacagggtct tccactcgtc gagcttcaag aggcgcccgg tggggttgcc
    25381 cggcgagcac acgtacacga gctgaatgtc gcgccaagtg gcctcgtcga tgctgctgaa
    25441 gtcagagccg aagtcgttct cgggcaggtt gttgatgaag atcggctcgg cgttggcgag
    25501 cagggccgcg ccttcataga tctggtagaa cgggttcggg cacagcacct tcgcgccggg
    25561 cctgccccca tcgaccacgc actgcgcgaa ggcgaacagc gcctcgcgcg tgcctgcgac
    25621 cgggatcacc tggctggccg ggtcgatctt cggcagcccg tagcggcgct ccagccagtg
    25681 cgcgatcgcg ccgcgcagcg catcgctgcc gagcgtggcg gggtagctcg acaggccgcc
    25741 gaggttgtcg gccagagtct ggcggatgaa acccggagtc ggatgctgcg gttcgccgat
    25801 cgaaagccgg atcggcttga gatgcgcggg cggctcgacg tcggcgaaga gggcgcgcag
    25861 tttttcgaag ggatagctct gcaggcgggc gaggttcgga ttcacgggga cgcgggctcc
    25921 ttggccggca atggacgcgg gcgccgagta tacctgcgta tggcggcgcc cgttggaagg
    25981 ccacgaggca cgcacgggcg cgggatcgcg cggcgcggcg cgcttgccag accgcgccgc
    26041 gtaaggtttc gatacgaggc caacgcgcgg gatgccttcg gcgcggtggt atgatgccgg
    26101 ccgcaaacgc ggggtgcgcc ggggcggatc gccgggctgc acgtcccgcc gtcttcccac
    26161 tgcccgctgt gcgtctctcc aagctcaaac tcgccggttt caagaccttc gtcgatccca
    26221 ccaccgtgct cacccccggc aacctcgtcg gcgtggtcgg gcccaacggc tgcggcaagt
    26281 cgaacatcat cgacgccgtg cgctgggtgc tgggcgagac gcgcgcgtcc gcgctgcgcg
    26341 gagagtcgat gcaggacgtg atcttcaacg gctcgaccac gcgcaagccg gtgtcgcgcg
    26401 cgagtgtcga gctggtcttc gacaacgccg agggcagggc agccgggcag tggtcgcgct
    26461 atgcggagat ctcggtcaag cgcgtgctcg accgttcggg cgagtcgacc tactacatca
    26521 acaacgtgca cgtccgccgc aaggacgtga tcgacctttt cctcggcacc ggcctggggc
    26581 cgcgcgccta cgcgatcatc gagcagggca tgatctcgcg catcatcgag gcgcgcccgg
    26641 aggagatccg cggcttcctc gaagaggccg cgggcgtcac caagtaccgc gagcggcgca
    26701 aggagaccga gggccgactg cgcgacgcac gcgacaacct cgcccgcctc gacgacatcc
    26761 gcatggagct cggcgagcgc atcgtgcatc tggaggcgca ggccgcggtg gcggcgcgct
    26821 accgcgcgct cgacgccgcg cacgtcgaga agcagcagct gttgtggctg gtcaagcgca
    26881 acgaggcgcg cgccgagcac ggccgcgtag cagcggcgct cgacgaggcg agcaggcgca
    26941 tcgaggccga cagcgcccgc ctgcaggagc tcgaggccgg cgtggaggcg cgacgcgacg
    27001 cgcacttcga ggcctccgaa gcggtgcatg tggcgcagaa cgacctcttc gcggtgagcg
    27061 ccgaggtcgc gcgcctggag accgagctgc agcacctcgg cgaggcgcgc aagcgtctgg
    27121 aggcgcgtct ggcgcagctc gagctcgacc gcgggcactg gtcctcgcgc cgcgaggcgc
    27181 tcgccgccga ccgcgagcgc tggcaggcgc tcgccgagaa cgccgcgctg cgcgccgagc
    27241 atgccgaagc ccgccacctg gagatcgccg atcgcctgcc cgagctggat tccgcccgcc
    27301 aggccgccga cgcgaccatg gccgcggcgc gccgcgagct cgcccagacc gagcagcagc
    27361 tgcgcgtgga ggagacccga cgcgcgagcg ccgtccgggc gctcgaagcc ctgcagcagc
    27421 gtcgcggccg gctcgaaggc gagcgcggcg cgatcgtcgg ccccgacgag cgtgtcctcg
    27481 ccgagcgcga ggcacgcctg gaggtggtgc aggacgagct ggaggcgctc cagcaggcgc
    27541 tcgccgaggc gcagccgcgc ctgcccgacg cgcaggccgc actgaaggcc gcgctcgagc
    27601 atgagcgcgc ggtgcagcgc cgtctgaccg agctgcgcgc gcggcgcgac gccctggtgc
    27661 agctgcaggc gcgcgtgcag tcccagggca agctgggaga ctggttgaag cgtcacggcc
    27721 tcgacgcgct gccgccgctg tggaagcagc tgcaggtgga ggacggctgg gacgaggcag
    27781 tgcaagccgt gctgcgcgag cgcctgtccg cgctcacctc gcccgatgcg gcggtggcgc
    27841 ttgcggccgc gcacaccgtg ctcgacgaga cgccaccgga gtcgctcgcc atcgcccttc
    27901 cggttacccc atcgacgctc gaccccgcag cctgcttcgc gcctgccgcc gcccctgcgt
    27961 ccagcaccga aacacccccc cctgtaggag cgccggcagg ggcgaacgcg tgcgacgagg
    28021 cgacgcaccc gtcagccacg gcattcgcgc tctccggcgg ccccgggccc agcgccgaag
    28081 cgccccccct tgtaggagcg ccggcaggcg cgaatgcgcg ggcgcttgcg cgcctggtcg
    28141 cggtgcgcga tccggccctg cgcgggctgg tgggtgactt cctggccggc gcgtgggcgg
    28201 tggagcggct ggacgactgg ctgccgcggt gcgcgcagct ggcaccgagc acctgcctgg
    28261 tggggccgcg cggacagatc ctgacccgcg gcgccttgat ccaccacgcc ccggatgcgc
    28321 gcacccacgg cgtgatcgag cgccagcgcg agatcgaggg ccttgccgcc gagttgcagg
    28381 cgcgcgagga cgaggcgcat ctggcgcacg acgcactgct gatggccgag acggcggcga
    28441 gcgagttgca ggaacgcatc aacggcctgc gccgcgagct gcagacgctg caggcgcagg
    28501 tgcacgcgga gcaggtcgag gtgctcaagc tcgcgcaggc gcgtgctcgc gccgaggagc
    28561 gccgcgagca gctcgcgcgc gacctcgaag acatcgtcca tctggagacc gccgagcgcg
    28621 agcacctcac gcgtgccgag ctcgagcagg cgcgtgcggc agagctcgcc gagctgcagc
    28681 gcgagcgcct cgatgccgcc accgaggtgc tgcgcgagcg cgagcatgcc gtgcgcgagg
    28741 cgcgcgcgct cgaacagtcg gcggcgcgcg agctgcagga ggcacggttc tccgaacgcg
    28801 aatgcgcggg caagctggag gacatcgcgc gcaaccagca gctcgccggc gagcagctcg
    28861 agcgcatcgt cgccgagctc gccacccgca gcgccgagct cgacgccacc gacgaccacc
    28921 gcagcgccga cgcgctgcag gaggcgttgg cgctgcgcgg ccgccgcgag gccgcgctcg
    28981 ccgcccgccg cgacgcgctc gccgaggccg ccgcggcgct caagcaggtc gaggagctgc
    29041 gcctgcgcac cgagcacgag gcggcgccga tccgcgcgcg cgtagccgag ctgcgcctcg
    29101 cgctgcaggc ggctgaaatc gcggttgccc agttcgagga gcgcctcgtc gaggcccgtg
    29161 ccgacgagac ggcgctccag ccgctgctcg ccgccgaccc gaaagaatcc accctgcagc
    29221 gcgaggtcgc ccgcctggcg cgggagatcg ccgagctcgg cgccgtcaac ctggccgcgc
    29281 tcgacgagct cgcgaccgcc tccgagcgca agggctacct cgacgcgcag acggaggacc
    29341 tgctgcaggc catcgacacc ctggaggatg ccatccgccg catcgatcgc gagacgcgcg
    29401 agcagcttca ggacacttac aatacggtca atcggcagtt cggcgccctg ttcccgcagt
    29461 tgttcggcgg cggacgggcc gaactggtgc tgaccggcga ggagatcctc gacgccggca
    29521 tccagatcgt cgcccagccg ccgggcaaga agaacgcgtc gatccacctg ctctcgggcg
    29581 gggagaaggc gctcaccgcg atcgcgctgg tgttctcgat gttccagctc aatccggcgc
    29641 cgttctgcat gctcgacgag gtggatgcgc cactggacga cacgaacacc gagcgctatg
    29701 cgaacatggt caagcgcatg tccgcgcaga cgcagttcat cttcatcagc cacagcaaga
    29761 tcacgatgga attcgcgcag cagctcgtgg gggtgacgat gcaggagcag ggcgtctcgc
    29821 gggtggtgga agtcgatatc gaagaggcgc tgcgcctggc cgacccggcc gcagcgtgac
    29881 gcaggacaag ctacacggag catttctggg atccaaatgg acagcgaact tcagatcgcg
    29941 ctgatcggcg ccggcatcgc cgcggtggtg ctggtggtgg gctacaacaa atggcaggag
    30001 cgccgccacc ggcgcgaggc cgaacgggcg ttcaagtcgg agcaccgcga cgtgctgctc
    30061 gagccgcgcg aggaaccggt cgcgggcgag cgccgcgaac ccggcatcgg cgccgccgag
    30121 ggcgagcctc gccgcttcaa cgaggcgccg atgaagcgca gcacgcccga gctgccgcgc
    30181 ctgctcgatc cgcgcgccga ctgcgtgatc cgcctcgaga ccatcgaagc gctcgaggtc
    30241 ggccgcgtgt gggcgatcca ggccgagcag ctcgccggac tcgccaagcc ggtgtactgg
    30301 ttcggcttca acgacgcaga gaacgtctgg cagccgctcg ggcccgacag cggcggcgcc
    30361 tgccactggt tctgcgccgc gctgcagctg gtcaatcgcg agggctcgat cggcgagacc
    30421 gacttcatgc gcttctcggg cggagtgcag cgcgtggccg acgcgctgat gagcctgccg
    30481 ccggcgctgc cgccgcgcgc cgagacgctg cgcaacgcca ccgagctcga tcgcttctgc
    30541 gccgacgttg acgtgcagat cggcgtcaat gtcgtcgcgc gcgatggcca gttcgagggc
    30601 cgcgcgattc acgccgtggc cgagaagcat ggccttcgcc tcggcgcgga cggcgcctac
    30661 cacatggtcg atggcgagca cagcgtgttt gcggtggcca acctcgagtc cggccgcttc
    30721 tcgcccgaga gcctcaaggg cctcgtcacg cgcgggctga ccctggtgat cgacgtgccg
    30781 cgggtggcca atggtggcgc cgccttcgac cgcatgatga agatggcgac cacgctcgcc
    30841 ggcgagctcg gcggcgacgt ggtcgacgac aatcgcgcgc ccttcggtgc cgaggcagcg
    30901 gcgatcatcc gcggccagat cgggcagttc cagagccgca tggccgacca cgacattccc
    30961 gccggcagcc cgctcgccct gcgcctgttc tccgtgtgat ggatctctct gccgataaca
    31021 gccccgctgc cagcgcgggc gaggtcgccg cacgcgcggc ggccctgcgc gccgagatcg
    31081 cgcgccacga ccatgcctac tacgtgctcg acgcgccgac gattcccgac gccgagtacg
    31141 accgcctgtt ccgcgagctg caggccatcg agcaggtcca cccggcgctg cgcagcgccg
    31201 actcgcccac gcagcgggtg ggcggcaagc cgctcgcgca gttcgccgcg gtgcgccacc
    31261 gcatcccgat gctgtcgatc cgcaccgaga ccgacaccga ggcgagcggg gccttcgtct
    31321 tcgattcccg tgtgcgcagc gcgctcaagc gcaacgacga agacccgccg atcgagtatg
    31381 ccgccgaact caagttcgat gggctggcga tcagcctgcg ctacgaggat ggcgtgctgg
    31441 tccaggccgc gacccgcggt gacggcgaga ccggcgagga cgtgaccgcc aacgtgcgca
    31501 ccgtcaaggc gattccgctg cgcctgcgcg gcgaggcgcc gccggtgctg gagatccgtg
    31561 gcgaggtgta catgcgccgc gacgatttcg agcgcctcaa cacccgccag gccgacgccg
    31621 gcgacaagac cttcgtcaat ccgcgcaacg ccgccgccgg cagcatccgc cagctcgacc
    31681 ccagcatcgc cgcgcgccga ccgttgtcct tttttgccta tggcctgggc gacaccggcg
    31741 agtggacgcc cccggcgacg cacgccgagg tgctcgatgt gatcgccgcc ttcgggctgc
    31801 cggtgtgcga gcaccgcgcg gtggtgcagg gggcacaggg gctcgcagac ttccacgcgc
    31861 gcatgggtgc gctgcgcgac acgctgccct tcgacatcga tggcgtggtg tacaaggtca
    31921 actcgcgcgc gctgcagcag cagctcggct tcgtgacccg cgagccgcgc tgggcggtgg
    31981 cgcacaagta ccctgcacag gaggcggtca cgctgctgcg cgacatcgag gtgcaggtcg
    32041 gccgcaccgg cgcgctgacc ccggtcgcgc gcctggaacc ggtcttcgtc ggcggcgtca
    32101 ccgtcaccaa cgccacgctg cacaaccagg acgagatcga ccgcaaggac gtgcgcatcg
    32161 gcgactgggt gatcgtgcgc cgtgccggcg acgtgatccc ggaggtggtc gcgccggtgc
    32221 tggagcgtcg cagcggcgag ccgccgcgct tcgtgctgct ggagcgattc cccacctgcc
    32281 cggtgtgcgg ctcgcacgtc gtgcgcggcg aggacgaggc cgtggcgcgc tgtaccggcg
    32341 gcttgttctg cccggcgcag cgcaagcagg cgctgctgca cttcgccggc cggcgtgcga
    32401 tggacatcga gggcctgggc gacaagctcg tcgaccagct cgtcgatgcg gcgatcgtga
    32461 agacgccggt cgatctgtac cgccttggcg tgcttgcgct cgccaacctc gagcgcatgg
    32521 gcgagaagtc ggcgcagaac ctgctgatgg cgatcgagaa gagccgcagc accacgctgg
    32581 cgcgcttcat cttcgcgctc ggcatccgca acgtcggcga ggccaccgcg cgcgacctcg
    32641 cgcgccactt cggcaatctc gatgcgctgg tcgcagccga cgtcgatgcg ctgcagcagg
    32701 tgcccgacgt gggcccgatc gtggcgcaat gcatcgccga cttcttcggc gagccgcaca
    32761 accgcgaggt gatcgagcag ttgcgcgccg ctggcgtgca gtgggccgag ggcgagccgc
    32821 agggcacggt ggccggtgcg ctcgcgggca agaccttcgt gctcaccggc acgctgccga
    32881 cgctgagccg cgacgaggcc aaggcgctga tcgaggcccg cggcggcaag gtcgcgggct
    32941 cggtgtcgaa gaagacgcac tacgtgatcg ccggcgccga ggccggctcc aagctcgaca
    33001 aggcgcaggc gctcgggctc gccatcctcg acgaggacgg gctgcgcgcg ctgctgaacg
    33061 aaacggatac aaacgcttga tgcaaagcgc gcacgcttgc cgcatgatcg cgcccgctgc
    33121 tgcgtcgcaa caccctcaat tcatgggaga gcaataaaaa tgaagaaagt caccaaggcg
    33181 attttcccgg ttgccggcat gggcacgcgc ttcctgcccg ccaccaaggc gagcccgaag
    33241 gagatgctgc cgatcgtcga caagccgctg atccagtacg ccgtcgaaga ggcggtcgcc
    33301 gccggaatca ccgacatgat cttcatcacc ggccgcacca agcgctcgat cgaggaccac
    33361 ttcgacaagg cctacgagct cgagaccgag ctcgaggcgc gcggcaagaa ggagttgctg
    33421 gagatcgtgc gcaagaccgt gccgaagggc gtcaactgca tctacatccg ccagtcggag
    33481 gcgctcggcc tcgggcacgc cgtgcagtgc gcgagtcacg tggtcagcga cgaggccttc
    33541 gcggtgatcc tcgccgacga cctgctggac aacaaggacg gcacgtcggt gctcaagcag
    33601 atggtggatg tctataacta ccaccgctgc tcggtgctcg gcaccatgaa cgtgccgcgc
    33661 gaggagaccc gcagctacgg catcgtcagc accgagtccg acaagggcca ggtgcagcgc
    33721 atgaccggca tcgtcgagaa gccgaagccc gaggaggcgc cgacgaccca ggcggtggtc
    33781 ggccgctaca tcctgacccc gcgcatcttc gatcacatcc gcgcgctcaa gccgggcgca
    33841 ggcggcgagt atcagctcac cgacgcgatc gcttcgctgc tcaaggagga ggcggtgctc
    33901 gcctaccagt tcaacggcgt gcgctacgac tgtggctcga agctcggcta cctgaaggcc
    33961 acgatcgagt tcggcctgcg tcatccggaa accggcccgg agtttgctca atacctcagc
    34021 ggtcgcttcg gcgcggagcc gtcggtcgcg aaaaagaagt agtacatcga gaagcccggc
    34081 gccggcagag cgcgcccgcc tgcagcgacc gccgcgttgg cggcgccctg caggcgggcg
    34141 cgctctgcgt ttaccggttc tgcgttgagg cggcgcgctc gattgaactg acagcgcacg
    34201 caaatcgcgc cgccctcggc agcttgcact gacagggacg ggaccccgtc cgaagcgtaa
    34261 cgccgcggca gtgatcatcc accaccaccg cggcgtcgtc gagcctgcta cttgcgcgtc
    34321 tcgacctgtt gcagcggctc gtcgacgacc accgcaaccg cgcgcggctt gcggccgaga
    34381 cggaccagct gctccaccgc gccgctgccg aactggccgc gcttggccgg gtcggtctcg
    34441 atcttgatca gcccgccatc accgggcggc accgagatcg gggcgctcgg agcctgag
//
LOCUS       DAOTIN010000026        34068 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_1406_length_34068_cov_9.359069, whole genome shotgun sequence.
ACCESSION   DAOTIN010000026 DAOTIN010000000
VERSION     DAOTIN010000026.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 34068)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 34068)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34068
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1406_length_34068_cov_9.359069"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(79..432)
                     /locus_tag="P5537_06080"
     CDS             complement(79..432)
                     /locus_tag="P5537_06080"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77647.1"
                     /translation="MNDEIEHLVATIDAHPEPLHADYTAEVRALVRIGLPALPAVLPL
                     LMAEAELTRLRAQRVLEGVTRAWAAEHAATAPQQAWEALWQAHGAYDWRAPAAARAAA
                     AARWQAWLAGRGGAP"
     gene            complement(429..1982)
                     /locus_tag="P5537_06085"
     CDS             complement(429..1982)
                     /locus_tag="P5537_06085"
                     /inference="COORDINATES: protein motif:HMM:NF012894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4157 domain-containing protein"
                     /protein_id="HRV77648.1"
                     /translation="MSFKAQRTHAPPAARKGTTASTHGGGSGTPRYLLAGRARVSARP
                     RPDEAAERDAERVASQWGGRPGGVRPALRVGAPARATPWSAPTTGHALPPDHAARASA
                     GLGVDGVRIHDDAHAARLAGSLGANAVTLGRDIYFAPGRYAPGTASGDRLLGHELAHV
                     AQQQGEPRALQCDLMQSMPVTLGIFDIGMATQAAPPGLSGTITFHPDPDGPYSAEIGL
                     IQAVNATDVAGTTTPASGAPVDWNNMVDANTGVRGTEAGRMEQMTQGTPGGAPAGWMI
                     DNLPSATPRGDPGSPNYIEHFGIGGNNQYGWLRSPTDVGPASLFDYPSLSFDSDLDFE
                     TVAKGTDNQTIYGAIAWGFQIRGGAVQGEYARVEDRASPVFEEALERFRGYYVHEPVV
                     LYFDTNQDIPLAGEEAKLADIPDYLDRYPDVTVGVQGNADVRGSEAGNWDLSQRRADA
                     VAGLLAQIGIDPGRIAYVSGFGETDMYSEHGTAPGARQPRDEGRLRANRRVVLEFSHS
                     VSNHPIVMP"
     gene            complement(1979..4018)
                     /locus_tag="P5537_06090"
     CDS             complement(1979..4018)
                     /locus_tag="P5537_06090"
                     /inference="COORDINATES: protein motif:HMM:NF012234.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HRV77649.1"
                     /translation="MKRPEDSVLRPPSATAPAPAATLADIGFACLGEGCGPGQGVEAD
                     WLLGQRERLGEPGGVDNDGRAAVEGRARAALARWLRDPPPADHALHALARHERLALAE
                     TMAVALARASELEPMAARALIWLQHPVGETRPTLGLLARLCDALGEPDALAALAGGAA
                     QAHGLIQLAPADRPLCERSVRLALPIVLALEGREGCFAGVDLRTDALPALAPSALEAA
                     RRHAAGLARDDDGARVLVIRAALEHEARAAATRVAEALGARPAFIAGDPPPGLAPWLW
                     LRRRLPVLCIPTAPGDHHRLPEIIGHRGPLLVATGNDGGFEAGGAVTQWRLPVPALAE
                     RIQLWRHSLGDALAPAAIEALASAHRHGAGRIVELAQAARSAAARAGEAVEGRHVGAV
                     ARSGVGAELGALAELLDEDIADDALVLAPALREALDALLVRCRLRDTLADALGRAART
                     RYRPGVRALFVGPSGTGKTLAASWVATRLGLPLFRVDLAAITSKYIGETEKNLSELFA
                     RAAHAEVVLLFDEADSLFGKRTDVKDANDRFANQQTNYLLQRIESHDGIVVLTSNSRA
                     RFDPAFTRRLDAILDFPAPGPDERRALWLAHLGDAHALDAAALNRIAAACDLAGGDIR
                     NVVLAAAARTHGHDRRIGEAELLAALAAEYRKLGKPLPTGMGAHPSRTDDKETRP"
     gene            complement(4015..5640)
                     /locus_tag="P5537_06095"
     CDS             complement(4015..5640)
                     /locus_tag="P5537_06095"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77650.1"
                     /translation="MIAERRVRHLGIRAPDAAGARRAGLLIEDALRTASLPGDGGELL
                     LVRRLRLPAFGAQASPQQVALGLESACRATAAVAGAESDDARLARASAVRFADALEAH
                     LALTTQLLGGRPARAWCWALAVPGYRPEEGVRAGLRRVALSLARREEAPVALACWWDA
                     LLAAGAAPRLLLALGADEAALLAARVRARRGALPDDGADADARHTLLRWVRTTFPPTD
                     ARRQLAESLTRDAPAGPASPPPEDIAGTAGSAAATRPPHALGDHRPGAEPGTKPQAQG
                     RTRLQETAGPGALDDHDGGRDGGRSLPLRESGAQQGPPPERPRHRQTPHAAAQAPAIA
                     QSEEPDGGGAGQRRDLPPAAVAAAQAAGRAAAPADAAPTRRAPYARRPDAPARPHTLA
                     LSQPTAAGGLLFLLPVLERLGLPEWLDAHPQHAATLPVHLLGHLLHRLQLAEDDPAWR
                     LGTPPPPGEPAVAAAAWLAACRRHLRLQAGIGPASLCLRPARLDLTSTHADVWLGMDQ
                     TDLRVRRAGLDLDPGWVPWFGRVVRFHYGPRPR"
     gene            complement(5645..10537)
                     /locus_tag="P5537_06100"
     CDS             complement(5645..10537)
                     /locus_tag="P5537_06100"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77651.1"
                     /translation="MSIRPIRHPLPGERILALAPEDAAEAARWWLRRPNLFAGRTLTG
                     PTLSARQDWAAAHVALRGRAFTAGVVQGLETALADVGSGLGGSRIALMQGSGLGASGE
                     DVHVARAHEFELGSLPVVADPSAFSGLGGAGGGGAVLAGKIVGPALGEVVAAAPAALP
                     RVGILVLQPVASERIGEFDLTDPCPLDACSGDGGAAFEDWRSGDAARLLWYAWPEEWR
                     SLPPLPPAGAGRWRNLIAWRIFEAERGLGEHAQLPWAPWGVALGLVACAADWTPLFLD
                     RASVVRAGARARWPRMGGGAGGLATHWRLPALWQAQIEQLAEQIAAAGDPPPPPASLG
                     ADFARLPPFGLLPAHVLELDSLRSDFFPGGFELDAAPIPSEQLDAALAEAAPLAPLDT
                     SLGERVRLLVPVPQAVFEPRLLIRELIDPEFAATLAAFTLARARQLGARQGLRTRAAL
                     LARAISGRSLAVPEIAADAEALEPESLAPWGPPPAGGGHRATLRDGIHQHFFEAATET
                     LAVAAGGELFAWVYLDPEQPPRTLMLQWHAGNWEHRAWWGEDLIPWGAAGTAAHARIG
                     ELPPSGRWVELRIPAALVGLDAQEVDGMAFTLFDGRAAWGITGSRAADGNARKWFCGV
                     LPADARSGGDEAWTLLTHNDLWAPFERIDGVEPADGRGAPAGGGHAAPAAADGGITEY
                     GLDGATAVLRADAGESLYAWVHLDPNAPPVQVLLEWHSSQGRHQAWWGLDRIPGASAA
                     NLVRTRAGALPRPARWVRLLVPAGGTAGIGMEGLEVRGMRFLLAGGGACFGATGVLDA
                     DGNERPWFAGSLPAGARQLGAWHFLGARDLLAPTSAGPRGQVAAALALYDDPLLGALS
                     VHERYQIFQRGLEGFIAFLKARADRADDLVDFNFVKVQTDIYRVRQIILGTSAATRLA
                     VSPALAAIAQSETAVASSARIAGFFDELKAEAATPGASADGGATAPARSALPGTTGAG
                     LRIGGGTEAVADATRADKRTLEIDKSADTKLFIRAVSEPRYTVSAAGAFLPSDVTGGA
                     PVVGRAEVRTVSIAERLQAPRATEAKDYTTATRHAAVSALTAHALALTAEDGGEVPGL
                     FLDIDLYGTRGDPALFYASAEELEKNVRLPAIDSDNPEDQALLDARPRNLAFTRLLRE
                     PWRMPLLLRTPLRVRVDEATQFADGTDLADNTVALMRQLEGRIKRYRDAIAAGQRVLD
                     ALRGSARALENRLRAIGDELAEARHDVAVTRALIAEEEARLAAINDRRSRILRDHVHF
                     IAYQRPREAESILPTAQRSLDPGLLAPAVPSCLHARQDAPDALRELLATVREAPARWF
                     AHAPALLDRLDRSDLLIKALQSAQLRSQLHALKLAAQPADTPAKGVPAAIAGLHGRRV
                     QAVQQARTASTRIDLAALATLGWKQARDEADKFVSLGDLIDGEHGSGAVASRAAALFD
                     ELSGIATCLHEAFCAVPPSIRLDWAERLSQFDATPQLRNLAGLARWGEIDFTARRRLQ
                     SLADWLFGQMRAGDVEAEALMNDIVHMTLLLASHAPVDRILSGRLPEPVTARPGIRLP
                     IRVTEPLRLRVGMQALIYQADRVVARATVEDLAGNTAAAVVTRVEGDAIALAVETRVH
                     FIDSSSPVALAGTMAGTRQG"
     gene            complement(10554..12569)
                     /locus_tag="P5537_06105"
     CDS             complement(10554..12569)
                     /locus_tag="P5537_06105"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77652.1"
                     /translation="MDLRTATARPTLAAAEVAALRAAGVLIEDPRRERPRYFDGRFLA
                     ARDLIRDQQYILAREADLGRAAGSGVAGGLEVSRGEGDRIEIAPGHGVTPAGELVVLP
                     RAASVRLGDIPHAEQLSARFGLGRIAQPPLRNRTGLFVLALRPVEFTDNPVGAYPTTI
                     TGPRTVEDADIVEATAVVLVPWNDDGAADALDARRGRAAATIFAGDGARALSSNVLAL
                     AMIALQNNVPVWIDTPLVRRELGADRADLPGLGHAPRALRLAHLLQHQLHLADALAAN
                     GGRGFAARERFALLPSAGPIPPGMIDVRDFTQRYFPAEMAVDLSIIPEDELPALVEES
                     LSLPPIDLTAAADTLESTAVLILAPVPRNEWRAVSARLADRLRALRPAAINLVATRKP
                     LEILQQLRIPRALPPSAPSDPVDAEWARLAALPTLWFVRRRNLAYRDAFAGEAIRLAG
                     LDRMDDLRPRLGGLGLDGALERVLATATPRAAVEVNSLLASPRFADSPALTAAAIGEL
                     TRAGSVDQAAVLRVAAELSAPGVGDGLVRLETARTDTAPSKTALRELASGEADWRGAD
                     RAAASASAEELAPLARKLLRPQPLRPPVTDTPPAADVAPVARTLSAAAPAASASPAAA
                     AAATSPSGRRRRSAAAPPATAPAAPSPAAPAPAKPAPRRRKPTSGGT"
     gene            complement(12658..13644)
                     /locus_tag="P5537_06110"
     CDS             complement(12658..13644)
                     /locus_tag="P5537_06110"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77653.1"
                     /translation="MNSPARPPADDPLYALPAAARPHYATGMLLGARDFADEQTYHRN
                     RLARALAFATGAGARRLPAGSLDAGDGSLGAIGLHGGGTLAGLRVLHRPAGTDHEEEL
                     RVAPGLAVDRLGRLVELGVPVCLRLERWFATELARDGGDDLRRAALDDPARFASARLR
                     AGAEALPARAVIADAFIRFVTCRQALAPAFASGPFDALDAVETARLRDGWELHLVLRG
                     DGLDDDFDGLPLRDPDLSALDPAARHDALQDAVLDAWPSLAGQLDANGDLPRPPGHPP
                     SLDPTAIFLARVFVAVGAGNPPERTGAVIVDNWGRRILPHLGLLAGALGAGL"
     gene            complement(13641..13943)
                     /locus_tag="P5537_06115"
     CDS             complement(13641..13943)
                     /locus_tag="P5537_06115"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77654.1"
                     /translation="MATFVRGQPITTREPTIKVDAGLAVGVHRFQLVVLTDTGQKSAP
                     VIAEVSIQRTILDPTRPILDTGVLTPTIPTRPRIDSTPVRPRAARPPKPRPPRSDT"
     gene            complement(13980..14291)
                     /locus_tag="P5537_06120"
     CDS             complement(13980..14291)
                     /locus_tag="P5537_06120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004387065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77655.1"
                     /translation="MAEFIINTEVKTETPTVEVTLSPQRPLALGRHTFRLVVVDDAGN
                     QSIPDDVVVIVADTEAPTAVLNAPRSVSLGQSFMLDGTRSFDLGGGQVTTYLWTYLGQ
                     G"
     gene            complement(14329..16857)
                     /locus_tag="P5537_06125"
     CDS             complement(14329..16857)
                     /locus_tag="P5537_06125"
                     /inference="COORDINATES: protein motif:HMM:TIGR02242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HRV77656.1"
                     /translation="MDANRQRFWLLADAAHWPWLEHVDHRPGCRALHLASERSLGATA
                     DDAAAIATAALERLPMAIDREGAHAWWDEGAGALLARSHLPGTATLLALPERPRDFAI
                     GHDDVLVVALTERLLLHDLRGRWPDALLPTPGFQAWRVAAAPGAGAWLLERGSGRLAR
                     LAGCMAVARPAAEYAAGTFRPQPENPSPLVMRVLDPLAWPAGERPQAMAVAEDGRPLL
                     LSWFGDGECRLRLIDAAGTVGAPQALTGVRFAYALDWLGDGRVVVRVPGRRDAPVFVP
                     RSTGAATSLVASGDVYPLQPEAIEAPFAHRLDQPPRYAVAGPALEPLHRLSVSHLARR
                     GEAASFAPADPTIPTEHARPAHLIDSGNQATVWHRLYAEARLPAGCGFIAWLATTADP
                     VPDGATDWHPHVFGDIPEADLPAGAVPHAAWERLPSELPGHPGLGAWGAPQPGRAGLW
                     TALVQRSSRRVRALAGRYLWVRLSLYGDGRDSPEIAALRIHGPRFSYRDHYLPRLYRE
                     TEFGPAADAPMSPLAPQSTPADFLERFLGNVEGWLTVLEDRVAAAHLASDPDVTAEPA
                     LDWLGGWIGVAFDAALPAPRRRDWLRRAADLARFHGTRRGLLLALDLASGGGVREGRI
                     AVLEGFRLRRLMSTLLGVDLNVEDDPLLPGLVVSGNSVVGDTLVLGEAERLELLALFR
                     DEVADNAERTAVLAFHDRLAYRSLVLLHGEHSAEELGLLRRIVELEAPAHVDVQIEQA
                     SWPLLVGVASLVGVDTWLGPARPPQPARADQSTLGRGDRVLGVGSLDPRLSGAASAAG
                     AIQPSADAGPDLRVTHGRSFVLDGSASLAPPGQHLAEYRWRLLD"
     gene            complement(16857..19163)
                     /locus_tag="P5537_06130"
     CDS             complement(16857..19163)
                     /locus_tag="P5537_06130"
                     /inference="COORDINATES: protein motif:HMM:TIGR02243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative baseplate assembly protein"
                     /protein_id="HRV77657.1"
                     /translation="MPILPPRLDDRSFDDLLEDLLARIPAHTPEWTHPRLGDPGRTLL
                     ELFAWLGDALLYRANLIPERQRLVFLKLLGQGLRPAQPATAVVGLGFAQPTELDGLTL
                     AAGATIKAPVPFETLAETTVLPIVAEACYKQPLGEAERARLAEVIDGLQRVHRIDGAA
                     RGYLVAPLFENGQAAREGVDVFAASLDHALWLALLAPAARPEQQAAVNAAARRALGGG
                     DSGSTARLSVGVVPAIAAPALFEEIGPRARVPVMWEIVTRSANGIDADYLTLEPLPGE
                     ADDTTAGLTRPGVLRLPMPDEALIWAPSNDVGENPRAGVGDNPPRIDDPERAARLIGW
                     LRLRPRPGSGVDSLKLAWVGVNAVEVDQRSTLSGRVLGVSTGAGDQVFQLPAGSVDAA
                     GLRIEVEEPGRGYRRWTRVDDLAALSVNAVVAREAAAFELDAEAGTLRFGDGVRGRVP
                     ERQMRIRLAYGRFGGGRAGNLPAGSLTEVAGARLVGSRRALPAIKVLQPLPTSGGEDA
                     ETLAAAERRIPALLRHRERAVTAEDYRRLALEVPGAEVGRVDVLPRFKPRERRFDVPG
                     VVSVMVLPARAPGPAPNPRPDRPFIERVHAHLAARTPLATECYVIGCEYVALGLAVAV
                     VIRDGFAREAVLFEVRETLRRLLWPLPPHGPGGAGWPLRRAVRERELEVEISRVAGVA
                     EVAGLNLFERGGTEGTPAWRLLTRNTADGSQQLDLSPWQLPELLGVLVVDVVPGSGAN
                     AAPSSLAALPNPFADDSAVAVPVVPEVC"
     gene            complement(19165..19563)
                     /locus_tag="P5537_06135"
     CDS             complement(19165..19563)
                     /locus_tag="P5537_06135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004385253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPW/gp25 family protein"
                     /protein_id="HRV77658.1"
                     /translation="MNEPLPRPLIGWPLFAVPDADGRLDWPGLEASVRHAIRVILSTR
                     PGEQLMRPEFGAGLDRLLHAPNNLSTRRQIRDWTMSALSRWERRILLDRVDVLEVPER
                     PSELRVEIAYRLARSGAADAVAVTVRLEEG"
     gene            complement(19560..21335)
                     /locus_tag="P5537_06140"
     CDS             complement(19560..21335)
                     /locus_tag="P5537_06140"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77659.1"
                     /translation="MVSHPHEVLLGPPRDLAAWPDEGSGAPAILQRSDDRFIEAVLAA
                     LRDPAGRIALRDDLARAEALATGVDSARRAGRGLFERLRAASGRLGLAGARTTAGKTA
                     DAEAAREKLRQAAEGRPLLKLFQPVQRQFHLAVMEARCDTPGRPRIDPAKVESAGLVI
                     RRLRRGADGRELKQGWMHAADGVRGWARVEHAATPLCPRHDPEAARRLARPSTGQPAL
                     DREIRAVLAAQDDALLSEAVMPMFVAPPDVCAAAGATLFYGLVPTTSSERAEGGAARL
                     DDETFGPHSSAFQSHLAGPLRGLGDGFPRPGQPLTPALAGLARSAPAAEERGAMQRLL
                     LLLRQLAVEFGAFEDGPEATALVTVLDGIGLPLADAAGKPVAGSVPAGSFLRTAARIL
                     LEGEDAAPAPAMPLGWPALDADTAGRLAEALSACLLQRFEALAGQAGRYDDPQARYVL
                     RAFVRLKPEGVCPARTVWSAYSPGFVIAPWFEGGGAPPVQVAMPDPSDREMLKKLKPN
                     VAFTVPASMQHLLSGDPLELMEGRKPEGNGLDLGWLCSFNIPVITICAFIVLNIFLSL
                     FDLFFRWMMFIKVCIPFPKKGGGGE"
     gene            complement(21329..22015)
                     /locus_tag="P5537_06145"
     CDS             complement(21329..22015)
                     /locus_tag="P5537_06145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004385205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein V"
                     /protein_id="HRV77660.1"
                     /translation="MDRAQPFLPPAGWMQSAMLARVVSIDDPEARDRVQLRLFAFDGV
                     DDQDAPLWARVVCPFAGDERGAFFMPDVGDEVLVVFVQGDARYPLVLGGLWNGSSAAP
                     ADLGSEGNRFKRIRSKNGVVVTLDDRQGQESLVLETPAGQRVTLGDGPSTITVEDANG
                     NRVVMNGSSIAFSAAAKLRIDAPQVEISAGMVKVDSALAEFSGIVKCQMVQTTAVVST
                     SYTPGAGNIW"
     gene            complement(22015..23106)
                     /locus_tag="P5537_06150"
     CDS             complement(22015..23106)
                     /locus_tag="P5537_06150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004385206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="contractile injection system protein, VgrG/Pvc8
                     family"
                     /protein_id="HRV77661.1"
                     /translation="MSTETSVSRSAVYRARPTLRLAGQADARVSELLVEMCVAETEGG
                     MSTAELRFSNWASTIDGSAEAAFEDGSRLTLGTAISVHAGDETQPRELFRGVVSGLEA
                     EFVQGGAPELVVLAEDALGRARMARRTRLFTDRSPADVVRAVAGELGLRPAVQGLDTP
                     VATWAQLNESDLAFLRRLLGRFDADLQIVGDELQVAPRSEVRRGELALELHGQLARAR
                     VVAELAHQVTRITVGGWNPVNGSAVSGEATTCAHAGPGTGTSGAEWLARALAPRSEHL
                     GHLALATDEEARAVAAAAFDQRARRFVRLDGVAEGNARLRVGTHVEVSGLSPRFDNTY
                     YVVEARHRYDLQTGYRTEFVGECAWLGAH"
     gene            complement(23117..23296)
                     /locus_tag="P5537_06155"
     CDS             complement(23117..23296)
                     /locus_tag="P5537_06155"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77662.1"
                     /translation="MPIIIEELEAEVRPERDDRGEDAPSATALPTPALLAAITAQLHR
                     ELRVREERRQRWQAD"
     gene            complement(23315..24361)
                     /locus_tag="P5537_06160"
     CDS             complement(23315..24361)
                     /locus_tag="P5537_06160"
                     /inference="COORDINATES: protein motif:HMM:NF039279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77663.1"
                     /translation="MPQQPPDLIDEPASFETLTGERFVVAVHFNPASLQYTVSNTLKD
                     EGKGAKKKQYVSQTTAKLSMDLVFDTTDIGEDVRVTTDRMARLLQPVAAGKDKNVPPT
                     VKFSWGAYAFTGLVEQYKETLDFFAAGGVPLRSSINLTLSSRDVVFESGTGQPVSVDT
                     TLGAEPVVTLADDGPGGAQGAANAAGDPHAARAIAAANGAASLRFGAGAGLAVGASMS
                     AGFAAGGSVGVDLAAGAGRTAGGAFQAGADATLLPAAAFAAGGATEAGAGLGIGAGMS
                     LSVGSSAETGFSALRSQATPSTHNLSTTALLPEAVELPTTGTVLAGGRMSGGGSGGLR
                     AEVGAEADFVIGPR"
     gene            complement(24372..24887)
                     /locus_tag="P5537_06165"
     CDS             complement(24372..24887)
                     /locus_tag="P5537_06165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004386237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HRV77664.1"
                     /translation="MMAAALDSRQQERLDNAPLGVFRFHVSFRPQPLRGAAGSELPLC
                     EGAFAECTGLEATMEPKVIKVGGANYGAVQRAGPVSFATVVLKRGMTRSRDNRQALWD
                     WFASVAGGAYAYRMEVEIEMRNGRDEPVLRWALRRALPVKFKAADLDARGTEVGIEEL
                     HLAHEGLVLVS"
     gene            complement(24884..26446)
                     /locus_tag="P5537_06170"
     CDS             complement(24884..26446)
                     /locus_tag="P5537_06170"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77665.1"
                     /translation="MRGLDFERAAQAQRPDPNRVDIACFVGFVARRDGALPAAVRAAL
                     ARARWTDGPWARPAAEVETLLQLPVTVDNWATFDALFAWEARPLGTGSGRCASALGAA
                     VRRFFACGGRRAVIVRCGDPWPHLEAAGARATHRAARLEALLAPGASAMDPSSWRGIG
                     HLHGLPETTLLCLPDLPDLCAADPATVAVATEPPAAAEVFVECSEGGSEGGGEDLALR
                     ALAPPRCDGAGFTAWRDAIGEVRLQLARHHRDKLLLAALPLPTHELRHAAAAGDTWAQ
                     ADMLGYLERSGMLAPAATGEGAATASAFVQLAWPWLRTAQGADLPGQLEAPDGLLAGL
                     VARNALARGTFRSVAGTPLPAVFGTEPVLPWSAIAATATDALARRVCVIAPQPGGGWA
                     LQSDVSTAADEAWRAGGVTRLMGAVLRAARTVAANTVFEASGPALWRSVERSLENTLN
                     AFWREGGLGGADPGEAFSVRCDLGTMSRNDLDNGRLRAQVSLLPAAALERITVVLELA
                     GAGAVATTNEVA"
     gene            complement(26475..26918)
                     /locus_tag="P5537_06175"
     CDS             complement(26475..26918)
                     /locus_tag="P5537_06175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004384929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HRV77666.1"
                     /translation="MAERITPYGAFNFIVNFDGGEEFGGFSDVSGIGTEVTVAEYRAG
                     NDKENHVRKVAGIHKVSDVTCKRGIVNFDSLWAWIEQTRSDGPAAQKTVAITLMDEAR
                     NPVRTWLLRGCIPMKYTGPTLAGKGGGDVAMEEIVLSAEGFEIQA"
     gene            complement(26936..28684)
                     /locus_tag="P5537_06180"
     CDS             complement(26936..28684)
                     /locus_tag="P5537_06180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004384930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HRV77667.1"
                     /translation="MPEYLAPGVYVEETSFRAKSIEGVGTSTTAFVGPTRKGPFRADT
                     NDQEVPELLTSYGDFERIYGGIADFGFSPATNYLAHAVRAFFNEGGSRLYVSRVVGSG
                     AATAAGAVTAEGTAADEAVAFVARFPGAIGNGRIVVREVLAPVALTAMNNAPAGSLLL
                     TGSGAAAAWHLKIGDTWHPAGSPADAAEDAATLAAATPRMATLLVVAIDGDGEDLSHE
                     GLGFDRSHPAWVGHVMAAAPGRRADHLQNLYAIAIGGNVGALELRNALFAGAGVNAAG
                     ELERSFALTGGSDGAAPGTDAYALALGELAGLEDVSIVAAPGSSAYPDAQAVANLLIS
                     HAEARRAYRIAVLDLPPAQLPGDARTLRGLIDSRYAAVYYPWVVVSNPLARPGREDIP
                     RELALPPSGFVCGIYARNDVERGVWKAPANEVVRGALRFELDINFAQQEMLNPIGVNC
                     LRYLSGRGFRVWGARLASSDPEWKYVNVRRYFNYLESSIDRGTQWAVFEPNGERLWAN
                     VRQTIADFLYNEWRNGALLGTKTEEAFFVRCDRSTMTQNDLDNGRLVCLIGVAVIKPA
                     EFVIFRIGQKTADARA"
     gene            complement(28748..29551)
                     /locus_tag="P5537_06185"
     CDS             complement(28748..29551)
                     /locus_tag="P5537_06185"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77668.1"
                     /translation="MNADTLRELERVEWRVLAALRPIDAITAATIVAPLRVTAEGARI
                     VRNRSGLYVIHEWPALAAHAAAFDAPPALPAPGSLALTVSVADPAGQYQPRLARIALP
                     RDPAAAGEDSLFSALPIALHPAPGARLGINWCALRVSLAHRTSGDALGGALLRVVAGD
                     AVLARGLSDWRGEALVAVAGIPVTTWSEDEDAVVVSHIAATLEAIFDPAAGTRTPMAH
                     VRAGHPPPRLPLVDPDAIESRRALLPRAQQDLSLAARGALNLNLGLDLP"
     gene            complement(29548..30135)
                     /locus_tag="P5537_06190"
     CDS             complement(29548..30135)
                     /locus_tag="P5537_06190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004373904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4255 domain-containing protein"
                     /protein_id="HRV77669.1"
                     /translation="MANVFGVHSVGSSIVTFLRNTYPGEIDGRALPACAFELVSAGQL
                     AGELEEGNRITLFLYRISVNEHRRQSARLRDEAGGAGPLGLDLHYLMSAWGMTPEDEQ
                     VSLTWALRQLHRHPVLDASSLTPEAGWDREEVVQIVPSELPTEDLMRIWDALSPSYRL
                     SVSWVARLVRIDPERDDTLHRPVVAGRFRYAEDAS"
     gene            complement(30162..30416)
                     /locus_tag="P5537_06195"
     CDS             complement(30162..30416)
                     /locus_tag="P5537_06195"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77670.1"
                     /translation="MEDRSLGEVMAAIEAYLACHPEAADSAEGIARWWLAARGIDTDA
                     DTVTQALQRLVEFGTVRVRRTPDGRRLYIATPPPAARRTH"
     gene            30851..>34068
                     /locus_tag="P5537_06200"
     CDS             30851..>34068
                     /locus_tag="P5537_06200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase family protein"
                     /protein_id="HRV77671.1"
                     /translation="MSIHVKLNHVTRYRYDRPVALSPQVVRLRPAPHCRTPIHAYGLK
                     VEPAGHFINWQQDPQSNYLARLVFPDKTTELRIEVDLVAELSVINPFDFFLEPAAEKI
                     PFAYEEALRIELAPYLAKAPAAALGPKFIDYLESIPRAPRASVDFLVTLNQRLQQDIR
                     YLVRLEPGVQTPEETLALASGSCRDSAWLLVQLLRHLGLAARFVSGYLIQLAPDIKSL
                     DGPSGSEVDFTDLHAWCEVYLPGAGWVGLDPTSGLFAGEGHIPLACSPEPSSAAPITG
                     FSDECECEFEHHMKVERVWEAPRVTKPYSEEQWAAIAALGHRIDGDLTAHDVRLTQGG
                     EPTFVSLDDRDGAAWNSDALDPQHRDASRPSKRTLAENLMFRLKDHYAPQGLLHFGQG
                     KWYPGEQLPRWSLNCYWRRDGEPVWHDPALFARELSGTAVDEALAARFLARVGERLGV
                     DTQWMMAAFEDAWYYLWRERRLPANVDPHDARVDDALERARLAKVFDQGLKQVVGHVL
                     PIVRNHMGSRRWQSGPWFLRAERLYLVPGDSPIGYRLPLDSQPWADKGDHPWIHPADP
                     NQGFPALPAHAELRQQLRPTGTTLGADSGLGFTAHGGGWTPSRVEHAGFHGAQAEAAM
                     PLPGAAEAALAARDERIDPARRPASFESAAWITRSAMCAEPRGGLLHLFMPPTAALED
                     YLEIVTAVEDTAAEFRLPVVLEGYEPPSDPRLAHFRITPDPGVIEVNVHPAASWDELV
                     ERTCTLYEEARQARLSTEKFMLDGRHTGTGGGNHFVLGGATPADSPFLRRPDLLRSLV
                     SYWHNHPSLSYLFSGLFIGPTSQAPRVDEARHDSVHELEVAFQQMPAPGAQVPPWLID
                     RLLRNLLIDATGNTHRAEFCIDKLYSPDSATGRLGLLELRAFEMPPHARMSLAQQLLL
                     RALIARFWQQPYAPARLRRWGTELHDRFLLPHWVAEDFRDVVTELREFGYALEFDWFA
                     PHFEFRFPRYGAFAARGVTMELRMALEPWHVMGEEGAPGGTVRYVDSSVERLQVKVSG
                     LNDDRHVLTCNGRTVPLQPTGTVGEFVAGVRYRAWQPPSCLHP"
BASE COUNT         4246 a        12032 c        13308 g         4482 t
ORIGIN      
        1 atcaatctgg gctacccagg ctgagccgtc aaacagcgtt acatgttcga cgcgtatgca
       61 cgccggcgtg ccgcgcgctc acggagcccc gccgcgtccg gcgagccagg cctgccagcg
      121 tgccgccgcc gctgcgcgcg ctgcggccgg agcgcgccag tcgtaggcgc cgtgcgcctg
      181 ccacaaggcc tcccaggcct gctgcggcgc ggtcgcggcg tgttcggccg cccacgcccg
      241 cgtcacccct tcgagcacgc gctgagcgcg cagccgggtg agctccgcct cggccatcag
      301 caagggcagc accgcgggca gggcgggcag gccgatgcgc accagcgccc gcacctccgc
      361 ggtgtagtcg gcgtgcaggg gctcggggtg ggcgtcgatg gtggcgacca ggtgttcgat
      421 ctcgtcgttc atggcatcac gatcggatgg ttgctgacgg agtgcgagaa ctcgagcacc
      481 acgcgccggt tcgcgcgcag gcggccctcg tcgcgcggct ggcgggcacc gggcgcggta
      541 ccgtgttcgg agtacatgtc ggtctcgccg aagcccgaga cataggcgat gcggcccgga
      601 tcgatgccga tctgcgcgag caggccggcc accgcgtcgg cgcggcgctg cgaaagatcc
      661 cagttgcccg cctcgctgcc gcgcacgtcg gcgttgccct gcacgccgac ggtgacgtcc
      721 gggtagcggt cgagatagtc ggggatatcc gcgagcttgg cttcctcgcc ggcgagcggg
      781 atgtcctggt tggtgtcgaa gtacagcacc acgggctcat gcacgtagta gccgcggaag
      841 cgctcgagcg cctcctcgaa gaccggcgag gcgcgatcct cgacgcgggc gtactcgccc
      901 tgcaccgcgc cgccccggat ctggaagccc cacgcgatcg caccgtagat ggtctggttg
      961 tcggtgccct tggcgacggt ctcgaagtcg aggtcgctgt cgaaggacag gctcggatag
     1021 tcgaacagcg aggccggtcc gacgtcggtg ggcgagcgca gccagccgta ctggttgttg
     1081 ccgccgatgc cgaagtgctc gatgtagttg ggcgagcccg gatcgccgcg cggggtggcc
     1141 gagggcaggt tgtcgatcat ccagccagcg ggggccccgc ccggcgtgcc ctgggtcatc
     1201 tgctccatgc ggccggcctc ggtgccgcgc acgccggtgt tggcgtcgac catgttgttc
     1261 cagtccaccg gcgcccccga tgcgggcgtg gtggtgccgg cgacgtcggt cgcattgacc
     1321 gcctggatca ggccgatctc cgcggagtag gggccgtccg ggtcggggtg gaaggtgatc
     1381 gtgcccgaca ggccgggcgg tgcggcctgt gtcgccatgc cgatgtcgaa gatgccgagg
     1441 gtgaccggca tgctctgcat caggtcgcac tgcagcgcgc gcggctcgcc ctgctgctgg
     1501 gcgacgtggg cgagctcgtg gccgagcagg cggtcgccgg acgcggtgcc cggcgcgtag
     1561 cggccggggg cgaagtagat gtcgcggccg agggtgacgg cgttggcgcc gaggctgccg
     1621 gcgagccggg cggcgtgcgc gtcgtcgtgg atgcgcacgc cgtccacgcc gagcccggcg
     1681 gatgcgcgcg cggcgtgatc cggcggcagc gcgtgcccgg tcgttggggc cgaccacggc
     1741 gtcgcgcgcg ccggcgcgcc gacccgcagc gcggggcgca cgccgcccgg gcggcccccc
     1801 cattgcgatg ccacccgctc ggcgtcgcgt tcggcggcct cgtccgggcg cgggcgggcg
     1861 ctgacgcggg cgcgtccggc gagcaggtag cgcggcgtcc cgctgccgcc gccatgggtc
     1921 gatgcggtgg tgcccttgcg cgccgcgggg ggggcgtgag tgcgctgtgc cttgaagctc
     1981 atggccgggt ttccttgtcg tcggttcggg atggatgcgc gcccatcccg gttggcaggg
     2041 gcttgccgag cttgcggtac tccgccgcca gcgcggcgag gagttcggcc tcgccgatgc
     2101 ggcggtcgtg cccgtgcgtg cgtgccgcgg cggcgagcac gacgttgcgg atgtcgccgc
     2161 cggcgaggtc gcaggctgcg gcgatgcggt tgagcgcggc agcgtcgagg gcgtgagcgt
     2221 cgccgaggtg ggcgagccag agggcgcggc gctcatccgg tccgggggcg ggaaagtcga
     2281 ggatggcgtc cagccgccgg gtgaaggccg ggtcgaagcg tgcgcggctg ttgctggtga
     2341 gcacgacgat gccgtcgtgg ctctcgatgc gctgcagcag gtaattggtc tgctggttgg
     2401 cgaagcggtc gttggcgtcc ttgacgtcgg tgcgcttgcc gaacagcgag tccgcctcgt
     2461 cgaacagcag caccacctcg gcatgggcgg cgcgggcgaa gagctcggag aggttcttct
     2521 cggtctcgcc gatgtacttg ctggtgatcg cggcgaggtc gacccggaac aggggcagcc
     2581 cgaggcgggt ggcgacccag ctcgcggcga gcgtcttgcc ggtgcccgag ggcccgacga
     2641 agagcgcgcg cacgcccggc cggtagcgcg tgcgtgcggc gcggccgagc gcgtcggcga
     2701 gggtgtcgcg cagccggcag cgcacgagca gcgcgtcgag cgcctcgcgc agcgcgggcg
     2761 cgaggacgag cgcgtcgtcg gcgatgtcct cgtcgagcag ttcggccagc gccccgagct
     2821 cggcaccgac gccgctgcgc gccaccgcgc cgacgtggcg gccttccacc gcctcgcccg
     2881 cgcgcgcggc ggccgagcgc gcggcctggg cgagctcgac gatccgcccc gcgccgtggc
     2941 ggtgcgcgct ggcgagggcc tcgatcgcag ccggggcgag cgcatcgccc aggctgtggc
     3001 gccacagctg tatccgctct gcgagcgctg gcaccggcag ccgccactgc gtgaccgcgc
     3061 cgccggcctc gaagccgccg tcgttgccgg tcgccaccag cagcgggccg cggtggccga
     3121 tgatctcggg caggcggtgg tggtcgccgg gcgcggtcgg aatgcagagc acgggcaggc
     3181 ggcggcgcag ccatagccag ggggcgaggc cgggcggggg atcgcccgcg atgaaggcgg
     3241 ggcgcgcgcc gagggcctcg gctacgcggg tggcggccgc gcgcgcctcg tgctcgagcg
     3301 cggcgcggat caccagcacg cgcgcgccgt cgtcatcgcg cgcgagcccg gcggcgtggc
     3361 gacgggcggc ctcgagcgcg gacggggcca gcgcgggcag cgcatcggtg cggaggtcga
     3421 cgccggcgaa gcagccctcg cggccctcga gtgcgagcac gatgggcagc gccaggcgca
     3481 cgctgcgctc gcacagcggg cgatctgccg gcgcgagctg gatcaggccg tgcgcctggg
     3541 ctgccccgcc cgcgagggcg gcgagcgcgt cgggttcgcc gagcgcgtcg cacagcctgg
     3601 ccagcaggcc gagggtcgga cgggtctcgc ccaccgggtg ctgcagccag atcagcgcac
     3661 gtgcggccat gggttccaac tcgctggcgc gcgccaaggc caccgccatg gtctcggcga
     3721 gtgcgagccg ttcgtggcgg gcgagggcgt gcaaggcgtg gtccgcgggc ggcgggtcgc
     3781 gcagccagcg tgcgagcgcc gcccgcgcgc ggccctcgac tgcggcgcgt ccgtcgttgt
     3841 cgacgccccc gggctcaccg agccgctcgc gctggcccag cagccagtcg gcctcgaccc
     3901 cttgaccggg gccgcagccc tcgccgaggc aggcgaagcc gatgtcggcg agcgtcgccg
     3961 ccggggcggg cgcggtggcc gaggggggcc gcaggacgga atcttccggg cgcttcatcg
     4021 tggcctcgga ccgtagtgga agcgcaccac ccgcccgaac cacggcaccc agccagggtc
     4081 gaggtcgagc ccggcgcggc gcacgcgcag gtcggtctgg tccatcccca gccagacgtc
     4141 cgcatgggtg gaggtgaggt cgagccgggc cgggcgcagg cacaggctgg ccgggccgat
     4201 gcccgcttgc aggcgcaggt ggcggcggca ggcggcgagc caggcggcgg ccgcgaccgc
     4261 gggttcgccg ggcggcggtg gcgtgcccag ccgccatgcg ggatcgtcct ccgccagctg
     4321 caggcggtgc agcaagtggc cgaggaggtg gacgggcagg gtggcggcgt gctgcggatg
     4381 ggcgtccagc cattccggca ggccgaggcg ttcgagcacc gggagcagga agagcaggcc
     4441 tcccgccgcg gtcggctggg agagggcgag cgtgtggggg cgggcgggcg cgtcgggacg
     4501 gcgcgcgtac ggtgcgcggc gcgtcggcgc agcgtccgcc ggcgccgccg cccgcccggc
     4561 ggcctgcgct gcggcgaccg cagcgggcgg gaggtcgcgc cgctgccccg caccgccgcc
     4621 gtccggctct tcgctttgcg cgatcgcggg cgcctgcgcg gccgcatgcg gtgtttgcct
     4681 gtggcggggg cgctccggcg gggggccctg ctgtgcgccg gactcccgca ggggcaagct
     4741 gcgcccgccg tcgcgcccgc cgtcgtggtc gtcgagggcg cccggccctg ccgtctcctg
     4801 caggcgcgtg cgcccctgcg cctgcggctt ggttcccggt tctgccccgg ggcggtggtc
     4861 gccgagcgcg tggggcggcc gtgtcgcggc tgcggagccg gcggtgcccg caatgtcctc
     4921 cggcggcggc gaggcgggcc ccgctggcgc gtcccgggtc agggactcgg cgagctggcg
     4981 gcgggcgtcg gtgggcggga aggtggtccg cacccatcgc aggagcgtgt gtcgcgcatc
     5041 cgcgtccgcg ccgtcgtccg ggagcgcgcc gcgccgggcg cggacgcggg cggccagcag
     5101 cgcggcttcg tccgcgccga gcgcgagcag gaggcggggc gcagcgccgg cggcgagcag
     5161 cgcgtcccac cagcacgcga gcgcgaccgg cgcctcctcg cggcgggcga gcgagagggc
     5221 gacccggcgc aggccggcgc gtacgccttc ttccggccgg tagcccggca ccgcgagggc
     5281 ccagcaccat gcgcgcgcgg ggcgaccgcc gagcagctgc gtcgtgagcg caaggtgggc
     5341 ctccagggcg tcggcgaagc gcacggccga cgccctggcg agccgggcgt catcgctctc
     5401 cgctcccgcc accgcggccg tcgcgcgaca ggccgactcc agcccgagcg ccacctgctg
     5461 cggcgaggcc tgcgcgccga atgccggcaa gcgcagccgc cgcaccaaca gcagctcgcc
     5521 gccgtcgccg gggaggctgg cggtgcgcag cgcatcctcg atgagcaggc ccgcacgccg
     5581 ggcccccgcg gcgtcgggcg cgcggatgcc gaggtggcgg acacggcgct cggcgatcat
     5641 ggcgctagcc ctggcgggtc cctgccatgg tgccggcaag cgcgaccggg ctggacgagt
     5701 cgatgaaatg cacccgcgtc tcgaccgcga gcgcgatcgc gtcgccctcg acccgggtca
     5761 ccacggcggc ggccgtgttg ccggcgaggt cctccaccgt ggcgcgcgcc accacgcggt
     5821 cggcctggta gatcagcgcc tgcatgccca cccggagccg cagcggctcg gtgacacgga
     5881 tcggcaggcg gatgcccggc cgggcggtga ccggctcggg caggcgcccg gacaggatgc
     5941 gatcgaccgg cgcatggctg gcgagcagca gggtcatatg cacgatgtcg ttcatcagcg
     6001 cctcggcttc gacgtcgccc gcccgcatct ggccgaacag ccagtccgcc agggactgca
     6061 ggcggcggcg cgcggtgaag tcgatctcgc cccagcgcgc cagtccggcc aggttgcgca
     6121 gctgcggcgt cgcgtcgaac tgcgacaggc gctccgccca gtcgaggcgg atcgacggcg
     6181 gcactgcgca gaacgcctcg tgcaggcagg tggcgatgcc cgacagttcg tcgaacagcg
     6241 ccgcggcccg gctcgccacc gcgccgctgc cgtgctcgcc gtcgatcagg tcgccgagcg
     6301 agacgaactt gtcggcctcg tcgcgcgcct gtttccagcc cagggtggcg agcgcggcga
     6361 ggtcgatgcg ggtgctcgcc gtgcgcgcct gctgcacggc ctgcacgcgc cggccgtgca
     6421 ggccggcgat ggcggcgggc acgcccttgg ctggcgtgtc cgcgggctgg gcggcgagct
     6481 tgagcgcgtg gagctggctg cgcagttgtg cgctctgcag ggccttgatg agcaggtcgc
     6541 tgcggtcgag gcggtcgagc agcgccggtg catgggcgaa ccagcgcgcc ggggcctcgc
     6601 gcaccgtggc gagcagctcg cgcagcgcgt cgggagcgtc ctgccgtgcg tgcaggcagc
     6661 tcggcaccgc gggcgcgagc aggccggggt ccaggctgcg ctgggcggtg ggcaggatcg
     6721 actcggcctc gcgcggacgc tggtaggcga tgaaatggac gtggtcgcgc aggatgcggc
     6781 tgcggcggtc gttgatcgcc gccaggcgcg cctcttcctc cgcgatcagg gcgcgcgtca
     6841 ccgccacgtc gtggcgtgcc tcggccagct cgtcgccgat cgcgcgcagg cggttctcga
     6901 gggcgcgcgc gctgccgcgc agggcgtcga gcacacgctg gcccgccgcg atcgcatcgc
     6961 ggtagcgctt gatccggcct tcgagttgac gcatcagcgc caccgtgttg tcggcgagat
     7021 cggtgccgtc ggcaaattgg gtggcttcgt cgacccgcac gcgcagcggc gtgcgcagca
     7081 gcagcggcat ccgccacggc tcgcgcagca gcctcgtgaa tgccaggttg cgcgggcggg
     7141 cgtcgagcag ggcctggtcc tccgggttgt cgctgtcgat cgccggcagg cgcacgttct
     7201 tctcgagctc ctccgcgctg gcgtagaaca gcgccgggtc gccgcgcgtc ccgtagaggt
     7261 cgatgtcgag gaacaggccc ggcacctcgc cgccgtcctc cgcggtcagc gccagcgcgt
     7321 gcgcggtgag cgcgctcacc gcagcgtggc gggtggcggt ggtgtagtcc ttggcttcgg
     7381 tcgcgcgcgg tgcctgcagg cgctcggcga tgctgaccgt gcgcacctcc gcccgcccga
     7441 ccacgggagc gccgccggtg acgtcggatg gcaggaaggc gcccgcggcg gagaccgtgt
     7501 agcggggctc gctgaccgcg cggatgaaga gcttggtgtc ggccgacttg tcgatctcca
     7561 gcgtgcgctt gtccgcgcgc gtggcgtccg cgacggcctc ggtcccgccc ccgatgcgca
     7621 ggcccgcgcc cgtcgtgccg ggcagcgcgc tcctggcggg ggcggtggcg ccgccgtccg
     7681 cgctggcgcc gggtgtggcg gcctccgcct tgagctcgtc gaagaagccg gcgatgcgtg
     7741 cgctggaagc caccgcggtc tcggactggg cgatcgcggc cagcgcgggc gataccgcca
     7801 ggcgggtggc ggccgaggtg ccgaggatga tctggcgcac ccggtagatg tcggtctgga
     7861 ccttgacgaa gttgaagtcc accaggtcgt ccgcgcggtc ggcgcgcgcc ttcaggaagg
     7921 cgatgaagcc ctccaggccg cgctggaaga tctggtagcg ctcgtgcacc gacagcgcgc
     7981 ccagcagcgg atcgtcgtag agcgcgagcg ccgccgcgac ctggcccctg gggccggccg
     8041 aggtgggggc gagcaggtcg cgtgcgccga ggaaatgcca tgcgccgagc tggcgcgcgc
     8101 cggcgggcag gctgcccgcg aaccacggcc gctcgttgcc gtcggcgtcg agcacgccgg
     8161 tggcgccgaa gcaggccccg ccgccggcga gcaggaagcg catgccgcgc acctccagcc
     8221 cttccatgcc gatgccggcc gtgccgcccg ccggcacgag gagccgcacc cagcgcgcgg
     8281 ggcgcggcag ggcgccggcg cgcgtgcgca cgaggtttgc tgcgctcgcg ccggggatgc
     8341 ggtcgagccc ccaccatgcc tggtgtcggc cctggctgct gtgccattcg agcaggactt
     8401 gcacgggcgg tgcgttgggg tcgagatgca cccacgcgta cagcgactcg ccggcgtcgg
     8461 cgcgcagcac ggccgtcgcg ccgtcgaggc cgtattcggt gatgccgccg tccgccgcgg
     8521 ccggcgccgc atgcccgccg ccggccggtg cgccgcgtcc gtccgccggc tcgacgccgt
     8581 cgatgcgctc gaagggcgcc cacaggtcgt tgtgggtgag cagggtccag gcttcgtcgc
     8641 cgccgctgcg ggcatcggcc ggcagcacgc cgcagaacca cttccgtgca ttgccgtccg
     8701 ccgcgcggct gccggtgatg ccccaggccg cgcggccgtc gaagagggtg aacgccatgc
     8761 cgtcgacctc ctgcgcgtcg agcccgacga gggcggcggg gatgcgcagc tcgacccagc
     8821 gcccgctcgg cggcagctcg ccgatgcggg catgggcggc cgtgcccgca gctccccagg
     8881 ggatgaggtc ttctccccac cacgcgcggt gttcccagtt gcccgcgtgc cactgcaaca
     8941 tcagcgtgcg tggcggctgc tccgggtcga ggtagaccca ggcgaacagt tcgccgccgg
     9001 cagccacggc gagcgtctcg gtggccgctt cgaagaagtg ctggtggatg ccgtcgcgca
     9061 gcgtcgcgcg atggccgccg cctgcggggg gcgggcccca cggcgcgagc gactcgggct
     9121 cgagcgcctc ggcgtcggcg gcgatctccg gcaccgcgag gctgcgcccg ctgatcgccc
     9181 gtgccagcag cgcggcgcgc gtgcgcaggc cctggcgggc gccgagctgg cgcgcgcgcg
     9241 ccagcgtgaa ggccgccagg gtggcggcga actcggggtc gatcagctcg cggatcagca
     9301 ggcgcggctc gaacaccgcc tgcggcaccg gcaccagcag acgcacgcgt tcgccgaggc
     9361 tggtgtcgag gggggcgagc ggggccgcct cggcaagcgc ggcgtcgagc tgctcgctcg
     9421 ggatcggtgc cgcgtcgagc tcgaatccgc cggggaagaa gtcgctgcgc aggctgtcga
     9481 gttcgagcac atgtgcaggc aacaggccga agggcggcag gcgggcgaag tccgcgccga
     9541 ggctggcggg cggcggtggc gggtcgccgg ccgcggcgat ctgctcggcg agctgttcga
     9601 tctgcgcctg ccacagcgcg ggcaggcgcc agtgtgtggc gaggccgccg gcaccgccgc
     9661 ccatgcgcgg ccagcgcgcg cgggcgcccg cccgcaccac gctggcgcgg tcgaggaaga
     9721 gcggggtcca gtccgcggcg caggccacca ggccgagcgc cacgccccac ggtgcccagg
     9781 gcagctgcgc atgctcgccc aggccgcgct cggcctcgaa gatgcgccag gcgatcaggt
     9841 tgcgccagcg cccggcgcct gcgggcggca gcggcggcag gctgcgccac tcctcgggcc
     9901 aggcgtacca gagcaggcgg gcagcgtcac cgctgcgcca gtcctcgaag gcggcgccgc
     9961 cgtcgccgga gcaggcgtcg agcgggcagg ggtcggtgag atcgaactcg ccgatgcgct
    10021 cgctggcgac cggctgcagc acgaggatgc cgacccgcgg cagggccgcc ggggccgccg
    10081 cgaccacctc gccgagcgcc gggccgacga tcttgcctgc gagcaccgcg ccgccgccac
    10141 cggcgccgcc gaggccggag aaggccgagg gatcggccac caccgggagg cttccgagct
    10201 cgaattcgtg ggcgcgggcg acgtgcacat cctcgccgct ggcgccgagg ccgcttccct
    10261 gcatcagcgc gatgcggctg ccgccgaggc cgctgccgac atcggcgagc gccgtctcca
    10321 gtccctgcac cacgcccgcg gtgaaggcgc ggccgcgcag ggcgacgtgg gccgcggccc
    10381 agtcctggcg ggcggacagc gtggggccgg tcagcgtgcg accggcaaac aggttgggcc
    10441 gccgcagcca ccagcgcgcg gcctcggccg cgtcttcggg agcgagggcg aggatgcgct
    10501 cgccggggag cggatgtcgg atcgggcgga tgctcacgat tcacctccag gcgtcaggtg
    10561 ccgccgctgg tcggcttgcg ccggcgtggc gcgggcttgg cgggcgcggg ggccgcaggc
    10621 gatggggccg cgggcgcggt cgccggcggg gctgcggcac tgcgccggcg ccggcccgag
    10681 ggcgaggtcg cggccgctgc ggcggcaggg ctcgccgagg ccgccggcgc ggcggcggac
    10741 agcgtgcgcg caaccggcgc cacgtcggcg gcgggcgggg tgtcggtaac gggcgggcgc
    10801 agcggctgcg ggcgtagcag cttgcgcgcg agcggcgcga gctcttccgc gctcgcgctg
    10861 gccgccgcgc gatcggcgcc gcgccagtcg gcctcgccgc tggcgagctc gcgcagcgcg
    10921 gtcttgctcg gtgcggtgtc tgtgcgcgcc gtctcgagcc gcaccaggcc gtcaccgacg
    10981 ccgggcgcgg agagttcggc ggccactctc agcacggccg cctggtccac gctccccgcg
    11041 cgcgtcagct cgccgatcgc cgccgcggtc agcgcgggag agtcggcgaa gcgggggctg
    11101 gcgagcaggc tgttcacctc gaccgccgcg cgcggcgtgg cggtggccag cacgcgctcg
    11161 agcgcgccgt cgaggccgag gccgccgagc cgggggcgca ggtcgtccat gcggtcgagg
    11221 ccggcgaggc ggatcgcctc gccggcgaag gcgtcgcggt aggcgaggtt gcgccggcgc
    11281 acgaaccaca gcgtgggcag cgcggccagc cgggcccatt cggcatcgac cggatcgctc
    11341 ggtgcggagg gcggcagggc gcgcggaatg cgcagctgct gcaggatctc cagcggcttg
    11401 cgggtggcga cgaggttgat cgcggccggg cgcagggcgc ggagacggtc ggcgaggcgt
    11461 gcggacaccg cgcgccactc gttgcgcggc accggggcga ggatcagcac cgcggtcgac
    11521 tccagcgtgt ccgcggcggc ggtgaggtcg atcggcggca ggctgagcga ctcctcgacc
    11581 agggccggca gctcgtcctc cgggatgatg gagaggtcca ccgccatctc ggcggggaag
    11641 tagcgttggg tgaagtcgcg cacgtcgatc atgccgggcg ggatcgggcc tgccgagggc
    11701 agcagcgcga agcgctcgcg cgcggcgaag ccgcggccgc cgttggccgc gagcgcatcg
    11761 gcgaggtgga gctggtgctg cagcaggtgg gcgagccgca gcgcgcgcgg ggcgtggccg
    11821 aggccgggca ggtcggcgcg gtcggcgccc agctcgcggc gcaccagagg ggtgtcgatc
    11881 cacaccggga cgttgttctg caaggcgatc atcgccagcg ccagcacgtt cgaggacagc
    11941 gcgcgcgcgc catccccggc gaagatcgtc gctgcggcgc ggccgcggcg cgcgtcgagc
    12001 gcgtcggcgg cgccgtcgtc gttccacggc accagcacca cggcggtggc ctcgacgatg
    12061 tcggcgtcct ccaccgtgcg cgggccggtg atcgtggtgg ggtaggcgcc caccgggttg
    12121 tcggtgaact ccaccgggcg cagcgcgagc acgaacaggc ccgtgcggtt gcgcagcggt
    12181 ggctgcgcga tgcggccgag cccgaagcgg gcggagagct gctcggcatg ggggatgtcg
    12241 cccaggcgca cgctcgccgc gcgcggcagc accacgagct cgcccgcggg ggtgacgccg
    12301 tggccggggg cgatctcgat gcggtcgccc tcgccgcggc tgacctccag gccgccggcc
    12361 acgccgctgc cggcggcgcg accgaggtcg gcctcgcgtg cgaggatgta ttgctggtcg
    12421 cggatcaggt cgcgcgcggc gaggaagcgg ccgtcgaagt agcgcgggcg ttctcgccgc
    12481 gggtcctcga tcagcacgcc ggcggcgcgc agcgcggcca cctcggctgc ggcgagcgtg
    12541 gggcgggcgg ttgcggtcct caggtccatg gtgaatcctc cggcgcgccc gggggcgcgc
    12601 gcatcggcag gcgggtcggc tgccgggttg tcatcgttct ctcgctccct cgccgcctca
    12661 caggcccgcg cccagggcgc cggccagcag gcccaggtgc ggcaggatgc gtctccccca
    12721 gttgtccacg atcaccgcgc cggtgcgctc gggtggattg ccggcgccga cggcgacgaa
    12781 gacgcgggcg aggaagatcg cggtggggtc caggctgggc gggtggccgg gcggacgcgg
    12841 caggtcgccg ttggcgtcga gctggccggc gaggctgggc caggcgtcga gcactgcgtc
    12901 ctgcagggcg tcgtgtcgcg ccgcggggtc gagcgccgag aggtcggggt cgcgcagcgg
    12961 caggccgtcg aagtcgtcgt cgaggccgtc gccgcgcagc accaggtgca gctcccagcc
    13021 gtcgcgcagg cgcgcggtct cgaccgcgtc gagggcgtcg aaggggccgc tggcaaacgc
    13081 gggggcgagc gcctggcggc aggtgacgaa gcggatgaag gcgtccgcga tcaccgcccg
    13141 cgcggggagc gcttcggcgc cggcgcgcag gcgcgcgctg gcgaagcggg cgggatcgtc
    13201 gagcgcggcg cggcgcaggt cgtcgccgcc gtcgcgcgcg agctcggtgg cgaaccagcg
    13261 ctccaggcgc aggcacaccg gcacgcccag ctccacgagg cggccgaggc ggtcgaccgc
    13321 gagccccggg gccacgcgca gttcctcctc gtgatcggtg cctgcggggc ggtggagcac
    13381 gcgcaggccg gccagcgtgc cgcccccgtg caggccgatc gcgccgaggc ttccgtcgcc
    13441 ggcgtcgagg ctgcctgcgg gcaggcggcg cgcgcccgcg ccggtggcga aagcgagcgc
    13501 gcgtgcgagg cggttgcggt ggtaggtctg ctcgtcggcg aagtcgcgcg cgcccagcag
    13561 catgccggtg gcgtagtgag gccgcgctgc ggcgggcagc gcatagaggg ggtcgtccgc
    13621 aggcggacgc gctgggctgt tcatgtgtcg ctcctcggcg ggcgcggctt gggcggccgc
    13681 gccgccctcg gtcggacggg cgtgctgtcg atgcggggcc gggtcgggat cgtcggtgtc
    13741 aggaccccgg tgtccaggat cggccgggtc ggatcgagga tcgtgcgctg gatgctgacc
    13801 tcggcgatga cgggggcgct cttctggccc gtgtcggtga gcacgacgag ctggaagcgg
    13861 tggacgccga ccgccagccc ggcgtccacc ttgatggtcg gctcgcgggt cgtgatcggc
    13921 tgtccgcgca cgaaagtggc catggttgtg ctccgctgac ggggccggtg gcgatgcgct
    13981 cagccctggc cgaggtaggt ccacaggtag gtggtcacct ggccgccgcc gaggtcgaag
    14041 gacctcgtgc cgtcgagcat gaagctctgg ccgaggctga ccgagcgcgg cgcgttcagc
    14101 accgcggtgg gcgcctcggt gtcggcgacg atgaccacca cgtcgtcggg gatggactgg
    14161 ttgccggcgt cgtccaccac gacgaggcgg aaggtgtggc ggcccagggc gagcggacgc
    14221 tgcggcgaca gcgtgacctc cacggtcggg gtctcggtct tgacttcggt gttgatgatg
    14281 aactcggcca tgatcggctc cttggtgggc gaaacggttt gaacgaggct agtcgagcag
    14341 ccgccagcgg tattcggcga ggtgctggcc gggcggtgcg agcgaggcgc tgccgtcgag
    14401 cacgaagctg cggccgtggg tgacccggag gtcggggccg gcgtcggcgg acggctgtat
    14461 ggccccggcg gcagaggctg cgcccgacag gcgcggatcc aggctgccga cgccgagcac
    14521 gcggtcgccg cggccgaggg tggattggtc cgccctcgcg ggctggggcg gtcgggcggg
    14581 gccgagccac gtatcgacgc cgaccaggct cgcgacaccc acgagcagcg gccagctggc
    14641 ctgctcgatc tgcacgtcta cgtgggccgg cgcctcgagc tcgacgatgc ggcgcaacag
    14701 gccgagctcc tccgcgctgt gttcaccgtg cagcagcacc aggctgcggt aggcgagacg
    14761 gtcgtggaag gcgaggacgg ccgtgcgctc cgcgttgtcg gcgacctcgt cgcggaacag
    14821 tgccagcagc tcgaggcgtt cggcttcgcc cagcaccagc gtgtcgccga ccaccgaatt
    14881 gccgctgacg accaggccgg gaagcagcgg gtcgtcctcg acgttcagat cgacgccgag
    14941 cagcgtcgac atcagccggc gcaggcggaa gccttcgagc accgcgatcc ggccttcgcg
    15001 caccccgccg ccgctggcga ggtcgagcgc cagcagcagg ccgcggcggg tgccgtggaa
    15061 gcgcgcgagg tcggccgccc ggcgcagcca gtcgcgccgc cgcggcgcgg gcagcgcggc
    15121 gtcgaaggcc acgccgatcc agccgcccag ccagtcgagc gcgggctcgg cggtgacgtc
    15181 ggggtcgctc gccagatggg cggcggcgac gcggtcctcc agcaccgtca gccagccttc
    15241 gacgttgccg aggaagcgct cgaggaagtc cgccggcgtg ctctgcggcg ccaggggcga
    15301 catcggcgcg tcggcggcgg ggccgaactc ggtctcgcgg tacagccgcg gcaggtagtg
    15361 gtcgcggtag gagaagcgcg ggccgtggat gcgcagcgcg gcgatctcgg gcgagtcacg
    15421 gccgtcgccg tacaggctca gccgcaccca caggtagcgc ccggcgagcg cacgcacgcg
    15481 ccggctgctg cgctgcacga gggcggtcca caggccggcg cgcccgggct gcggggcgcc
    15541 ccaggcgccc aggccggggt ggccgggcag ctcggagggc aggcgctccc aggcggcgtg
    15601 cggcaccgcg cccgcgggca ggtctgcttc cggaatgtcg ccgaacacgt gcggatgcca
    15661 gtcggtggct ccgtccggga cggggtcggc ggtggtggcc agccaggcga tgaagccgca
    15721 gccggcgggc aggcgcgctt cggcgtagag gcggtgccag accgtggcct ggttgccgct
    15781 gtcgatcagg tgtgctggcc gggcgtgttc ggtgggaatc gtcggatcgg cgggggcgaa
    15841 gctggcggcc tcgcccctgc gtgccaggtg cgagaccgag agccggtgca gcggctcgag
    15901 cgccgggccg gccaccgcat agcggggcgg ctggtcgagg cgatgggcga agggcgcctc
    15961 gatcgcctcg ggctgcagcg gatacacgtc gccgcttgcg accaggctgg tcgccgcgcc
    16021 ggtggagcgc ggcacgaaga ccggcgcgtc gcggcggccg ggcacgcgca cgacgacccg
    16081 gccgtcgccg agccagtcga gcgcgtaggc gaagcgcacg ccggtgagcg cctgcggggc
    16141 gccgaccgtg cccgcggcgt cgatcaggcg gagccggcat tcgccgtcgc cgaaccagga
    16201 cagcagcagc gggcgcccgt cttcggcgac cgccatcgcc tgtggccgct cgccggccgg
    16261 ccaggcgaga ggatcgagca cacgcatcac gagcggcgac ggattctcgg gctgcgggcg
    16321 gaaggtcccc gccgcgtact cggcggccgg tcgcgcgacc gccatgcagc cggcgaggcg
    16381 ggccagccgc ccgctgccgc gttcgagcag ccaggcgccc gcgcccggcg ccgcggcgac
    16441 ccgccaggcc tggaagccgg gggtcggcag cagcgcatcg ggccagcgcc cgcgcaggtc
    16501 gtgcagcagc agacgctcgg tgagcgcgac cacgagcacg tcgtcgtggc cgatggcgaa
    16561 atcgcgcggg cgttcgggca gggcgagcag cgtggccgtg ccgggcaggt ggctgcgcgc
    16621 gagcagcgcg ccggcgccct cgtcccacca ggcgtgcgcg ccctcgcggt cgatcgccat
    16681 cggcaggcgc tccagcgccg cggtggcgat ggccgcggcg tcgtctgccg tcgcccccag
    16741 gctgcgctcg ctggccaggt gcaatgcacg gcagccgggg cgatgatcga cgtgctcgag
    16801 ccagggccag tgggccgcgt cggcgagcaa ccagaagcgc tggcggttgg cgtccatcag
    16861 cacacctcgg gtacgaccgg cacggcgacc gcgctgtcgt cggcgaaggg gttgggcagc
    16921 gcagcgagcg aggacggcgc cgcgttcgcg ccgctgccgg gcacgacatc gacgacgagc
    16981 acgccgagca gctcgggcag ctgccagggg ctgaggtcga gctgctgcga gccgtccgca
    17041 gtgttgcggg tgagcagtcg ccaggcaggt gtgccctcgg tcccgccgcg ttcgaacagg
    17101 ttcaggccgg cgacctcggc gacgccggcg acgcgcgaga tctccacctc gagctcgcgc
    17161 tcgcgcaccg cccggcgcag cggccagccc gcaccgcccg gcccgtgggg cggcagcggc
    17221 cagagcaggc ggcgcagagt ctcgcgcacc tcgaacagga ccgcctcgcg ggcgaagccg
    17281 tcgcggatca cgaccgccac cgccaggccg agcgcgacat actcgcagcc gatcacgtag
    17341 cactcggtgg cgagcggggt gcgtgcggcg agatgggcat gcacgcgctc gatgaagggg
    17401 cggtcggggc gggggttggg cgcggggccg ggcgcacgcg cgggcagcac catcacgctg
    17461 accacaccgg gtacgtcgaa gcgccgctcg cgcggtttga agcgcggcag cacgtcgacg
    17521 cggccgacct cggcgccggg cacctccagc gccaggcggc ggtagtcctc ggcggtcacc
    17581 gcgcgctcgc gatggcggag cagcgcgggg atgcggcgct cggcggcggc gagggtctcg
    17641 gcgtcttcac cacccgaggt ggggaggggc tggagcacct tgatcgcggg cagcgcgcgc
    17701 ctgctgccga cgaggcgcgc gccggcgacc tcggtgaggc tgcccgcggg caagttgccg
    17761 gcgcgtcctc cgccgaagcg gccgtaggcc aggcggatgc gcatctggcg ctccggcacg
    17821 cggccgcgca cgccgtcgcc gaagcgcagc gtgccggcct cggcgtcgag ctcgaaggca
    17881 gccgcttcgc gggcgaccac ggcattcacg gacagcgcgg cgaggtcgtc gacccgcgtc
    17941 caccggcggt agccgcggcc cggttcctcc acctcgatgc gcaggccggc ggcgtccacc
    18001 gagccggcgg ggagctggaa gacctggtcg ccggcaccgg tcgacacgcc cagaacccgg
    18061 ccggagaggg tggagcgctg atccacctcc accgcgttga cgccgaccca ggccagcttg
    18121 aggctgtcga ccccgctgcc cgggcgcgga cgcaggcgca gccagccgat caggcgcgcg
    18181 gcgcgctcgg ggtcgtcgat ccgtgggggg ttgtcgccga cgccggcgcg cgggttctcg
    18241 ccgacgtcgt tggacggggc ccagatcagc gcctcgtcgg gcatgggcag gcgcagcacg
    18301 ccgggccggg tgagcccggc ggtggtgtcg tcggcttcgc ccggcagcgg ctcgagcgtc
    18361 aggtagtcgg cgtcgatgcc gttggcgctg cgggtgacga tctcccacat caccggcacg
    18421 cgggcgcgcg gcccgatctc ctcgaacagc gccggcgcgg cgatcgccgg caccacgccc
    18481 accgacagcc gtgcggtgct gccgctgtcg ccgccgccga gggcgcggcg cgcggcggcg
    18541 ttgaccgcgg cctgctgctc gggccgtgcc gccggggcga gcagggcgag ccagagcgcg
    18601 tggtcgaggc tggcggcgaa gacgtccacg ccctcgcgtg ccgcctggcc gttctcgaac
    18661 agcggcgcga ccaggtagcc gcgggcggcg ccgtcgatgc ggtgcacgcg ctgcaggccg
    18721 tcgatgactt cggcgagccg ggcgcgctcg gcttcgccga gtggctgctt gtagcaggcc
    18781 tcggcgacga tcggcagcac ggtggtctcg gcgagggtct cgaagggcac gggcgccttg
    18841 atcgtcgcgc cggcggccag cgtcaggccg tcgagctcgg tgggctgggc gaagccgagg
    18901 ccgacgacgg cggtggcggg ctgcgccggg cgcaggccct ggccgagcag cttcaggaac
    18961 accaggcgct ggcgctcggg gatgaggttg gcgcggtaga gcagcgcgtc gcccagccag
    19021 gcgaagagct cgagcagcgt gcgccccggg tcgcccaggc gcggatgcgt ccattccggg
    19081 gtgtgcgccg ggatgcgcgc gagcaggtcc tcgagcaggt cgtcgaagct gcggtcgtcg
    19141 aggcgcggtg gcaggatcgg catgtcagcc ctcctccagt cggacggtga ccgccacggc
    19201 gtcggcggcg ccggagcggg cgagacggta ggcgatctcc acccggagct cgctcgggcg
    19261 ctcggggact tcgagcacat ccacgcggtc gagcaggatg cggcgctccc agcggctcag
    19321 cgccgacatc gtccagtcgc ggatctggcg gcgggtggag aggttgttgg gggcgtggag
    19381 caggcggtcg aggccggcgc caaactccgg gcgcatcagc tgctcgccgg ggcgggtgct
    19441 gaggatgacg cggatcgcat ggcgcacgct ggcctcgagg ccgggccagt cgaggcggcc
    19501 gtcggcgtcg ggcactgcaa acagcggcca gccgatcagc gggcgcggaa ggggctcgtt
    19561 cattcgccac ctccaccctt cttcgggaag gggatgcaga ccttgatgaa catcatccag
    19621 cggaagaaga gatcgaacag cgacaggaag atgttgagca cgatgaaggc gcagatcgtg
    19681 atgaccggga tgttgaaact gcacagccag ccgagatcca gcccgttgcc ctccggcttc
    19741 ctgccctcca tcagctcgag cggatcgccc gagagcaggt gctgcatcga ggccggcacg
    19801 gtgaaggcca cgttgggctt gagcttcttc agcatctcgc ggtcgctcgg gtcgggcatc
    19861 gccacctgca ccggcggcgc gccgccgccc tcgaaccagg gcgcgatcac gaagccgggg
    19921 ctgtaggcgc tccataccgt gcgcgcgggg cagaccccct ccggcttgag gcgcacgaag
    19981 gcgcgcagca cgtagcgcgc ctgcggatcg tcgtagcgcc cggcctggcc ggcgagcgcc
    20041 tcgaagcgct gcagcaggca ggccgacaag gcctcggcga gccgtccggc ggtgtcggcg
    20101 tcgagcgcgg gccaccccag cggcatggcg ggcgcgggcg ccgcgtcctc gccttcgagc
    20161 aggatgcggg cggcggtgcg caggaagctg cccgcgggca cgctgcctgc gacgggcttg
    20221 ccggcggcgt ccgccagcgg caggccgatg ccgtcgagca ccgtgaccag ggccgtggcc
    20281 tcggggccgt cctcgaaggc gccgaactcc accgcgagct ggcgcagcag cagcagcagg
    20341 cgctgcatcg cgccgcgctc ctcggcggcg ggcgcgctgc gtgcgaggcc ggcgagcgcg
    20401 ggcgtcaggg gctggccggg gcgcgggaag ccgtcgccga ggccgcgcag cggccccgcg
    20461 aggtgggact ggaaggcgct cgagtgcggt ccgaaggtct cgtcgtccag acgtgccgcg
    20521 ccgccttcgg cgcgctcgct gctggtggtc ggcacgaggc cgtagaagag ggtcgcgccg
    20581 gccgcggcgc acacatcggg cggagccacg aacatcggca tcaccgcctc ggacagcagc
    20641 gcatcgtcct gcgccgccag cacggcgcgg atctcgcggt cgagtgcggg ctggccggtc
    20701 gatgggcgcg ccagccgtcg cgctgcctcc gggtcgtggc gggggcacag tggcgtggcg
    20761 gcgtgttcga cccgggccca gccgcgcacg ccgtcggcgg cgtgcatcca gccctgcttc
    20821 aactcgcgtc catcggcgcc gcggcgcagg cggcggatca ccaggccggc ggactccacc
    20881 ttcgccgggt cgatgcgcgg gcgtccgggc gtgtcgcagc gcgcctccat gacggcgagg
    20941 tggaactggc gctggacggg ctggaacagc ttgaggagcg gccggccttc cgcggcctgg
    21001 cgcagcttct cgcgtgcggc ttcggcatcc gcggtcttgc cggcggtggt gcgtgcgccg
    21061 gccagcccga ggcggccgct ggcggcgcgc aggcgctcga acagcccgcg gccggcgcgg
    21121 cgcgcgctgt cgacgcccgt ggcgagcgct tcggcgcggg cgaggtcgtc gcgcagcgcg
    21181 atgcgtcctg ccgggtcgcg cagggcggcg agcaccgcct cgatgaagcg gtcgtcgctg
    21241 cgctgcagga tcgccggtgc gccgctgccc tcatccggcc aggcggcgag atcgcgtggt
    21301 ggcccgagca ggacctcgtg gggatggctc accatatgtt tcccgctcct ggcgtgtagc
    21361 tggtcgacac caccgcggtg gtctgcacca tctggcactt gacgatgccg gagaactcgg
    21421 cgagcgcgct gtccaccttg accatgccgg cgctgatctc gacctgcggc gcgtcgatcc
    21481 tgagcttggc ggccgcgctg aaggcgatgc tgctgccgtt catgacgacg cggttgccgt
    21541 tggcgtcctc gaccgtgatc gtgctcgggc cgtcgccgag ggtgacgcgc tgcccggcgg
    21601 gggtctcgag caccaggctc tcctgtccct ggcggtcgtc gagcgtgacc acgacaccgt
    21661 tcttcgagcg gatgcgcttg aagcggttgc cttcgctgcc caggtcggcg ggagcggcgc
    21721 tgctgccgtt ccacagcccg ccgagcacga gcgggtagcg tgcgtcgccc tgcacgaaca
    21781 cgacgagcac ctcgtcgccg acgtcgggca tgaagaaggc gccgcgctcg tcgccggcga
    21841 aggggcagac gacgcgcgcc catagcggtg cgtcctggtc gtcgacgccg tcgaaggcga
    21901 acagccgtag ctgcacgcgg tcgcgcgcct cggggtcgtc gatggagacc acccgggcca
    21961 gcatggccga ctgcatccag ccggcggggg ggaggaaggg ctgtgcgcgg tccatcagtg
    22021 cgctcccagc caggcacact cgccgacgaa ttcggtgcgg tagccggtct gcaggtcgta
    22081 gcggtggcgc gcctcgacga cgtagtaggt gttgtcgaag cgcggcgaca ggccgctgac
    22141 ctccacgtgc gtgcccacgc gcagccgggc gttgccctcg gcgacgccgt ccaggcgcac
    22201 gaagcggcgt gcgcgctggt cgaaggcggc cgcggccacg gcgcgcgcct cctcatcggt
    22261 ggcgagggcg aggtggccga ggtgttcgct gcggggcgcg agcgcgcgcg ccagccactc
    22321 ggcgccgctg gtgcccgtgc ccgggcctgc atgggcgcag gtggtggcct cgccggagac
    22381 ggcgctgcca ttgaccgggt tccagccccc cacggtgatg cgggtgacct ggtgggccag
    22441 ctcggcgacg acgcgcgccc gcgcgagctg gccgtgcagc tcgagcgcca gctcgccgcg
    22501 acggacctcg ctgcgcggcg ccacctgcaa ctcgtcgccg acgatctgca ggtcggcgtc
    22561 gaagcgcccg agcaggcggc gcaggaaggc gagatcgctc tcgttgagct gggcccaggt
    22621 ggcgaccggc gtgtccagcc cctgcacggc gggacgcagg ccgagctcgc ccgccaccgc
    22681 gcgcaccacg tcggccgggc tccggtcggt gaacagccgg gtgcggcggg ccatgcgcgc
    22741 gcgtcccagc gcgtcctcgg cgagcacgac cagttcgggg gcgccgccct gcacgaactc
    22801 ggcctccagc ccgctgacca cgccacggaa gagctcgcgc ggctgggtct cgtcgccggc
    22861 atggacgctg atcgcggtac cgagggtgag ccggctgccg tcctcgaagg cggcctcggc
    22921 actgccgtcg atggtgctcg cccagttgga gaagcgcagc tcggcggtac tcatgccgcc
    22981 ctcggtttcc gcgacgcaca tctcgacgag caactcggat acgcgtgcgt cggcctgtcc
    23041 ggccaggcgc agcgtggggc gtgcgcgata gacggcggag cggctgacgg aggtctcggt
    23101 gctcatcgtc gcgctcctag tcggcctgcc agcgttggcg gcgctcttcg cgcaccctca
    23161 gctcgcgatg cagctgcgcg gtgatcgcgg cgaggagcgc aggcgtcggc agcgccgtgg
    23221 cggacggcgc atcctcgccg cgatcgtcgc gctcgggccg gacctcggcc tccagttcct
    23281 cgatgatgat cggcatgtct gcttctcccc gttgctagcg cgggccgatg acgaagtccg
    23341 cctcggcgcc gacctcggcg cgcaggccgc cactgccgcc gccactcatg cggccaccgg
    23401 cgagcaccgt gccagtggtc ggcaactcga ccgcctcggg cagcagggcg gtggtcgaca
    23461 ggttgtgggt ggatggagtg gcctggctgc gcagggccga gaaccccgtc tccgcggagc
    23521 tgccaaccga caggctcatg cccgcgccga tgccgaggcc ggcacccgct tccgtggcgc
    23581 cgcccgcggc gaaggcggcg gcgggcagca gggtggcgtc ggcgccggcc tggaacgccc
    23641 ctccggcggt tcgccccgcc cccgctgcga gatccacgcc gaccgagccc ccggcggcga
    23701 acccggcgct catcgaggcg cccaccgcga gccccgcgcc ggcgccgaag cgcaggctgg
    23761 cggcgccgtt ggcggcggcg atggcgcgcg ccgcgtgcgg gtcgccggcg gcattggccg
    23821 cgccctgggc gccgcccggg ccgtcgtcgg cgagcgtcac caccggctcg gcgcccaggg
    23881 tcgtgtcgac cgagaccggc tggccggtac cgctctcgaa caccacgtcc cggctcgaca
    23941 gggtgaggtt gatcgaggaa cgcaagggca cgccgcccgc ggcgaagaaa tcgagcgtct
    24001 ccttgtattg ctcgaccagg ccggtaaagg cgtaggcgcc ccagctgaac ttcaccgtcg
    24061 gcggcacgtt cttgtccttg ccggcggcga ccggctgcag cagacgggcc atccggtcgg
    24121 tggtgacgcg cacgtcctcg ccgatgtcgg tggtgtcgaa caccaggtcc atggacagct
    24181 tggcggtggt ctggctgacg tactgcttct tcttcgcgcc cttgccctcg tccttgaggg
    24241 tgttggagac ggtgtattgc aggctggcgg gattgaagtg caccgccacg acgaagcgct
    24301 ctccggtgag ggtctcgaag ctcgccggtt cgtcgatcag gtcggggggc tgttgcggca
    24361 tggtcgtggc ctcagctcac cagcaccagg ccctcgtggg ccaggtgcag ctcctcgatg
    24421 ccgacctcgg tgcccctggc gtcgaggtcg gcagccttga acttgaccgg cagcgcgcgc
    24481 cgcagcgccc agcgcagcac cggctcgtcg cgtccgttgc gcatctcgat ctccacctcc
    24541 atgcggtacg cgtaggcgcc gccggcgacg ctggcgaacc agtcccacag cgcctggcgg
    24601 ttgtcgcggc tgcgggtcat gccgcgcttg agcacgacgg tggcgaagct gaccggcccc
    24661 gcgcgctgca ccgcaccgta gttggcgccg ccgaccttga tcaccttcgg ttccatggtc
    24721 gcctccaggc cggtgcactc ggcgaaggcc ccctcgcaca gcggcagctc gctgcccgca
    24781 gcccccctga gcggctgcgg gcggaaactg acgtggaagc ggaagacgcc gagcggggcg
    24841 ttgtcgaggc gttcctgctg cctgctgtcg agcgctgcgg ccatcatgcg acctcgttgg
    24901 ttgtggcgac cgcgccggcg ccggcgagct cgagcacgac ggtgatgcgc tcgagcgcgg
    24961 ccgccggcag caggctgacc tgcgcgcgca ggcggccgtt gtcgaggtcg ttgcggctca
    25021 tcgtgccgag gtcgcagcgc acgctgaagg cctcgccggg gtcggcgccg ccgaggcctc
    25081 cctcgcgcca gaaggcgttc agggtgttct cgaggctgcg ctcgacgctg cgccacagcg
    25141 ccgggccgct ggcctcgaag accgtgttcg cggccaccgt gcgcgcggcg cgcagcaccg
    25201 cccccatcag acgggtgacg ccgccggcgc gccaggcctc gtcggctgcc gtgctgacgt
    25261 cggactgcag cgcccagccg ccgccgggtt gcggtgcgat cacgcacacg cggcgagcga
    25321 gggcgtcggt ggcggtggcg gcgatcgcgc tccagggcag caccggctcg gtgccgaaga
    25381 ctgccggcag cggcgtgccc gccaccgagc ggaaggtgcc gcgggcgagc gcgttgcgcg
    25441 cgacgaggcc ggcgagcaag ccgtccgggg cttcgagctg gccgggcagg tcggcgccct
    25501 gcgcggtcct gagccagggc caggccagct gcacgaaggc gctcgcggtc gccgcgcctt
    25561 caccggtggc ggcgggcgcc agcatgccgc tgcgctcgag gtagcccagc atgtccgcct
    25621 gcgcccaggt gtcgcccgca gcggcggcgt ggcgcagctc gtgcgtgggc aggggcaggg
    25681 cggcgagcag cagcttgtcg cggtggtggc gggcaagctg caggcgcacc tcgccgatcg
    25741 cgtcgcgcca ggccgtgaac cccgcgccgt cgcagcgcgg cggggccagc gcgcgtaggg
    25801 cgaggtcctc gccgccgccc tcgctcccgc cctcgctgca ctcgacgaag acctccgccg
    25861 cggccggcgg ttcggtcgcg accgccaccg tcgcggggtc ggcggcgcac aggtcgggca
    25921 ggtcggggag gcacagcagg gtggtctcgg ggaggccgtg caggtggccg atgccgcgcc
    25981 agctcgacgg atccatcgcg ctcgcgccgg gcgccagcaa ggcctcgagg cgcgcggcgc
    26041 gatgcgtggc gcgcgcgccg gcggcttcga ggtgaggcca gggatcgccg cagcgcacga
    26101 tcaccgctcg ccggccaccg caggcgaaga agcggcgcac ggcggcgccc agcgcgctgg
    26161 cacagcgtcc ggagccggtg ccgagcgggc gcgcctccca ggcgaagagc gcatcgaagg
    26221 tggcccagtt gtctaccgtc accggcaact gcagcagggt ctcgacctcg gcggcggggc
    26281 gtgcccacgg accatcggtc cagcgcgcgc gcgccagggc cgcgcgcacc gccgcaggca
    26341 gcgcgccgtc gcgacgcgcg acgaagccga cgaagcaggc gatgtcgacc cggttcgggt
    26401 ccggccgctg tgcctgcgcc gcgcgttcga agtcgaggcc tctcatgatc ggtgtccggg
    26461 tggctggggc agcctcaggc ctggatctcg aagccttcgg ccgacagcac gatctcttcc
    26521 atggccacgt cgccgccgcc cttgccggcc agcgtggggc cggtgtactt catcgggatg
    26581 cagccgcgca gcagccaggt gcgcaccggg ttgcgcgcct cgtccatgag cgtgatcgcc
    26641 acggtcttct gcgccgcggg gccgtcgctg cgggtctgct cgatccacgc ccacaggctg
    26701 tcgaagttca cgatcccgcg cttgcaggtg acgtcgctga ccttgtggat gccggcaacc
    26761 ttgcgtacgt ggttttcctt gtcgttgccg gcgcggtatt cggcgaccgt gacctcggtg
    26821 ccgatgcccg acacgtcgga gaagccgccg aactcctcgc cgccgtcgaa gttgacgatg
    26881 aagttgaagg cgccgtaggg cgtgatgcgt tcagccatga ttcagtcccc ctcgttcagg
    26941 cacgggcgtc ggccgtcttc tggccgatgc ggaagatgac gaactcggcc ggcttgatca
    27001 ccgccacgcc gatcaggcac accaggcgac cgttgtcgag gtcgttctgg gtcatggtgc
    27061 tgcggtcgca gcgtacgaag aaggcttcct cggtcttggt gccgagcagc gcgccgttgc
    27121 gccactcgtt gtagaggaag tcggcgatcg tctggcgcac gttggcccac aggcgctcgc
    27181 cgttgggctc gaacaccgcc cattgcgtgc cgcgatcgat cgaggactcc agatagttga
    27241 agtagcgccg cacgttgacg tacttccact ccgggtcgga cgaggccagg cgcgcacccc
    27301 acacgcggaa gccgcgtccc gacaggtagc gcaggcagtt cacgccgatc gggttgagca
    27361 tctcctgctg ggcgaagttg atgtcgagct cgaagcgcag cgccccgcgc acgacctcgt
    27421 tggcgggcgc cttccacacc ccgcgctcga cgtcgttgcg ggcgtagatg ccgcacacga
    27481 agcccgaggg cggcagcgcc agctcgcgcg ggatgtcctc gcgccccggg cgggcgagcg
    27541 gattcgacac gacgacccag gggtaataga ccgcggcgta gcgcgagtcg atgaggccgc
    27601 gcagcgtgcg cgcgtccccc ggcagctgtg cggggggcag gtcgagcacc gcgatgcggt
    27661 aggcgcggcg cgcctcggca tgcgagatca gcaggttggc gaccgcctgc gcgtcggggt
    27721 aggccgagct gcccggcgcc gcgacgatcg agacgtcttc cagcccggcg agctcgccga
    27781 gggcgagcgc gtaggcgtcc gtgcccgggg cggcgccgtc gctgccgccg gtgagggcga
    27841 agctgcgctc gagctcgccg gcggcattga cgccggcgcc ggcgaagagc gcgttgcgca
    27901 gttcgagcgc gccgacgttg ccgcctatgg cgatcgcata gaggttctgc aggtggtcgg
    27961 cgcgccgtcc cggcgcggcc gccatcacgt gacccaccca ggcgggatgg ctgcgatcga
    28021 agccgaggcc ttcatggctg aggtcctcgc catcgccgtc gatcgccacg accagcagcg
    28081 tcgccatgcg cggcgtggcg gcggcgaggg tggcggcgtc ctcggcggcg tccgcggggc
    28141 tgcccgccgg gtgccaggtg tcgccgatct tgaggtgcca ggccgccgct gcgccgctgc
    28201 cggtgagcag caggctgccg gcgggggcgt tgttcatggc ggtgagtgcc accggggcga
    28261 gcacctcgcg taccacgatg cggccgttac cgatcgcgcc cgggaagcgc gccacgaagg
    28321 ccaccgcctc gtcggcggcg gtgccttccg cggtgaccgc gccggcggcc gtcgctgcgc
    28381 cgctgcccac gacccgcgac acgtagaggc gagagccgcc ctcgttgaag aaggcgcgca
    28441 cggcgtgggc gaggtagttg gtcgccgggc tgaagccgaa gtctgcgatg ccgccgtaga
    28501 tgcgttcgaa atcgccgtag ctggtcagca gctcgggcac ctcctggtcg ttggtgtcgg
    28561 cacggaaggg gcccttgcgc gtcggaccga cgaaggcggt ggtgctggtg cccacgccct
    28621 cgatggactt ggcgcggaag ctggtttcct cgacatagac gccgggagca aggtactcgg
    28681 gcatggctgg tctcctttta tcgagcgtgc cgggcggtgt tcatgcccag gtgaacggac
    28741 tccgatctca tggcaggtcg aggcccaggt tgaggttcag cgccccgcgt gcggcgaggc
    28801 tgaggtcctg ctgcgcgcgc ggcagcaggg cgcggcggga ttcgatggcg tcggggtcga
    28861 ccagcggcag gcggggcggc gggtggccgg cgcgcacatg ggccatcggc gtgcgggtgc
    28921 ccgccgcggg gtcgaagatc gcttcgagcg tggcggcgat gtggctcacc accaccgcat
    28981 cctcgtcttc cgaccaggtc gtcaccggga tgccggccac cgccaccagc gcttcgccgc
    29041 gccagtccga cagcccgcgc gcgagcacgg cgtcgccggc caccacccgc aacagggcgc
    29101 cgcccagcgc atcgccgctc gtgcggtgag cgagactcac ccgcagcgcg caccagttga
    29161 tgccgaggcg ggcgcccggg gccggatgga gcgcgatggg gagcgcggag aacagcgaat
    29221 cctcgccggc ggccgcgggg tcgcgcggca gggcgatgcg ggccaggcga ggctggtact
    29281 ggccggcggg gtcggcgacg gacaccgtca acgccagact gccgggcgcg ggcagggcgg
    29341 ggggggcgtc gaacgcggcg gcgtgggctg cgagcgccgg ccattcgtgg atgacgtaga
    29401 gcccgctgcg gttgcgcacg atgcgcgcgc cttccgccgt cacccgcagc ggcgcgacga
    29461 tggtggcggc ggtgatcgcg tcgatcggcc gcaacgccgc cagcacgcgc cattcgacgc
    29521 gctcgagttc gcgtagcgtg tccgcgttca cgatgcgtcc tccgcgtagc ggaagcggcc
    29581 ggcgaccacc gggcgatgta gcgtatcgtc gcgctcgggg tcgatgcgca cgaggcgggc
    29641 gacccaggag acggacaggc ggtaggatgg gctcagcgca tcccagatcc gcatgaggtc
    29701 ttcggtgggt agctcggagg ggacgatctg gacgacctct tcgcggtccc agccggcttc
    29761 cggcgtcagc gacgaggcgt cgagcaccgg atgccgatgc agctggcgga gcgcccaggt
    29821 cagcgaaacc tgctcgtcct cgggggtcat gccccaggcg ctcatcaggt agtgcaggtc
    29881 gagaccgagc gggccggctc ctccggcctc gtcgcggagc cgggcgctct ggcggcggtg
    29941 ctcgttgacc gagatgcggt acaggaacag cgtgatgcgg ttgccctcct cgagctcgcc
    30001 ggcgagctgg ccggcgctga cgagctcgaa tgcgcacgcc ggcagcgccc ggccgtcgat
    30061 ctcgccgggg taggtgttgc gcaggaaggt cacgatcgag cttcccaccg aatgcacgcc
    30121 gaatacgttc gccatctccg ctccgtgtcc ttgcgtcgcc gtcaatgcgt ccgtcgcgcg
    30181 gccgggggcg gggtcgcgat gtacagccgg cgtccgtcgg gcgtgcgccg gacgcgcacc
    30241 gtgccgaact cgaccaggcg ctgcagcgcc tgcgtcaccg tgtcggcgtc ggtgtcgatg
    30301 ccgcgtgccg cgagccacca gcgcgcaatg ccctcggcgc tgtccgctgc ctcggggtgg
    30361 caggcgagat aggcctcgat ggccgccatg acttccccga ggcttcgatc ctccatgctt
    30421 gccgcctccc gacaaggtct cccgggcaac ctagcgagtt ccgtgccggt gccgaaggaa
    30481 tgggaaaaag ctcttttaat cagtgtcttg atgtcggttt ttcacgctct ccggtcgagc
    30541 tgcccgcgtg cgcggtgggt cgaaaaccac ccgccggaaa gaggggcggt gctgtggatg
    30601 ccggtcgcag caaggtggct gccccgaccg caggggcgga cgcgcgcctg ggtcggccgc
    30661 agcgccccgg gtcgtcggtg acccgctccc gtttccgggc gcgcgatgca ccggcgcggt
    30721 gcgcttgcgg ggcggaattg gtgcgcttga tggaaggagc cgccgcaggc agtgcgtttg
    30781 cggggggatt cgccgcgcgc atggttcttg ctgggatcac atcggtttcc gtaccgcctg
    30841 cgaggctccc gtgtccatcc acgtcaagct caaccacgtc acccgttacc gctacgaccg
    30901 cccggtcgcg ctgtcgccac aggtcgtgcg cctgcgcccg gcgccgcact gccgcacgcc
    30961 gatccacgcc tacgggctga aggtcgagcc tgccgggcac ttcatcaact ggcagcagga
    31021 cccgcagtcg aactacctcg cccgcctcgt cttcccggac aagaccaccg agctgcgcat
    31081 cgaggtcgac ctggtcgccg agctgtcggt gatcaacccc ttcgatttct tcctcgagcc
    31141 ggcggcggag aagatcccct tcgcctacga ggaggccctg cgcatcgagc tcgcccccta
    31201 tctggcgaag gcgcctgcgg cggcgctcgg gccgaagttc atcgattacc tcgaatccat
    31261 cccgcgcgcg ccgcgtgcga gcgtggattt cctggtcacg ctcaaccagc gcctgcagca
    31321 ggacatccgc tacctggtgc gcctggagcc gggcgtgcag acgccggagg agacgctggc
    31381 gctggcgagc ggctcgtgtc gtgactcggc ctggctgctg gtgcagttgc tgcgccacct
    31441 cgggctggcg gcgcgcttcg tgtcgggcta cctgatccag ctcgcgcccg acatcaagtc
    31501 gctcgacgga ccctcgggca gcgaggtcga cttcaccgac ctgcacgcct ggtgcgaggt
    31561 ctacctgccc ggcgcgggct gggtgggcct cgacccgacc tcggggctgt tcgccggcga
    31621 gggccacatc ccgctcgcgt gctcgcccga gccttcgtcg gcggcgccga tcaccggctt
    31681 cagcgacgaa tgcgagtgcg aattcgagca ccacatgaag gtcgagcgcg tatgggaggc
    31741 gccgcgcgtc accaagccct acagcgagga gcaatgggcg gcgatcgcgg ccctgggcca
    31801 tcgcatcgac ggcgacctga cggcccacga cgtacgcctc acgcaaggcg gcgagcccac
    31861 cttcgtgtcg ctcgacgacc gcgacggcgc ggcctggaac agcgacgcgc tcgacccgca
    31921 gcaccgcgat gcatccaggc cgagcaagcg cacgctggcc gagaacctga tgttccgcct
    31981 caaggaccac tacgcgccgc agggcctgct gcacttcggc cagggcaagt ggtatccggg
    32041 cgagcagctg ccgcgctggt cgctgaactg ctactggcgg cgcgacggcg agccggtctg
    32101 gcacgacccg gcgctgttcg cgcgcgagct ctccggcacc gcggtggacg aagccttggc
    32161 ggcgcgcttc ctcgcccgcg tcggcgagcg cctgggcgtc gacacgcagt ggatgatggc
    32221 ggccttcgag gacgcctggt actacctgtg gcgcgagcgc cggctgccgg ccaacgtcga
    32281 tccgcatgat gcacgggtgg acgacgcgct cgaacgcgcg cggctcgcca aggtcttcga
    32341 ccaggggctg aagcaggtgg tcggccacgt gttgccgatc gtgcgcaacc acatggggtc
    32401 ccggcgctgg cagagcggtc cgtggttcct gcgcgccgag cgcctgtacc tggtccccgg
    32461 cgactccccg atcggctacc gcctgccgct cgattcgcag ccgtgggcgg acaagggcga
    32521 ccatccctgg atccaccccg ccgatcccaa ccagggcttt ccagcgctgc ccgcgcacgc
    32581 cgagctgcgc caacaactgc ggccgaccgg gacgaccctc ggcgccgata gcggcctcgg
    32641 cttcaccgcc cacggtggcg gctggacgcc gagtcgcgtc gagcatgccg gcttccatgg
    32701 tgcgcaggcc gaggccgcga tgcctctgcc cggcgcggcc gaggccgcat tggccgcccg
    32761 cgacgagcgc atcgaccccg cccgccgccc ggcgtccttc gagtccgcgg cgtggatcac
    32821 ccgcagcgcg atgtgcgccg agccgcgcgg cggcctgctc catctcttca tgccgcccac
    32881 ggcggcgctg gaggattacc tcgagatcgt caccgccgtc gaggacaccg ccgccgagtt
    32941 caggctgccg gtggtgctcg aaggctacga gccgccctcc gatccgcgcc tcgcgcactt
    33001 ccgcattacc cccgacccgg gcgtgatcga ggtcaacgtc caccccgcgg cgagctggga
    33061 cgagctcgtc gagcgtacct gcacgttgta cgaagaggcc cgccaggccc gtctgtcgac
    33121 cgagaagttc atgctcgacg gccgccacac cggcaccggc ggcggcaacc acttcgtgct
    33181 cggcggcgcc accccggccg attcgccctt cctgcgccgg cccgacctgc tgcgcagcct
    33241 ggtgagctac tggcacaacc atcccagcct gtcctacctg ttctcggggc tcttcatcgg
    33301 cccgacctcg caggcgccgc gggtggacga ggcgcgccac gactcggtgc atgagctgga
    33361 agtggccttc cagcagatgc cggctccagg cgcccaggtt ccgccctggc tcatcgaccg
    33421 cctgctgcgc aacctgctca tcgacgccac cggcaacacc caccgcgccg agttctgcat
    33481 cgacaagctc tacagcccgg acagcgccac cgggcggctg ggcctgctcg agctgcgcgc
    33541 gttcgagatg ccaccgcacg cgcgcatgag cctcgcccag caactcttgc tgcgcgcgct
    33601 gatcgcgcgc ttctggcagc agccctacgc ccccgcccga ctccggcgct ggggcaccga
    33661 gctgcacgac cgcttcctgc tgccgcactg ggtggcggag gatttccgcg acgtcgtcac
    33721 cgagctgcgc gagttcggct atgcgctcga gttcgactgg ttcgcgccgc acttcgagtt
    33781 ccgcttcccc aggtacggtg cgtttgccgc gcgcggtgtc accatggagc tgcgcatggc
    33841 gctcgagccc tggcacgtga tgggcgagga gggcgcgccc ggtggtaccg tgcgctacgt
    33901 cgattcctcg gtggagcgcc tgcaggtgaa ggtttccgga ctcaacgacg accgccatgt
    33961 gctgacctgc aacggccgca cagtgccgct gcagcccacc ggcacggtgg gcgagttcgt
    34021 cgccggcgtg cgctatcgcg cctggcagcc gccgtcctgc ctgcatcc
//
LOCUS       DAOTIN010000027        33438 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_1451_length_33438_cov_9.209418, whole genome shotgun sequence.
ACCESSION   DAOTIN010000027 DAOTIN010000000
VERSION     DAOTIN010000027.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 33438)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 33438)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33438
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1451_length_33438_cov_9.209418"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..659)
                     /locus_tag="P5537_06205"
     CDS             complement(<1..659)
                     /locus_tag="P5537_06205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011288496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV77672.1"
                     /translation="MSNMLLEGKEIHTYYGASHILHGIDFNIREGEGIALMGRNGMGK
                     STLIKSMLGIVRPRHGRVLVRGDDYTRARTFQTAQQGIAYVPEGRGIFKSLTVRENLL
                     MSARAGVDGRREWTFDRVMETFPRLGERINNGGWQLSGGEQQMLTIGRALMTNPDLLI
                     LDEATEGLAPLIAMEIWRIVKEIRRTGIATVIVDKNHGAVTSICDRAMILVKGQVVFD
                     GT"
     gene            complement(652..1425)
                     /locus_tag="P5537_06210"
     CDS             complement(652..1425)
                     /locus_tag="P5537_06210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004265868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV77673.1"
                     /translation="MSTTKNEVLLQADKLTRRFGGLVANQDISVTLERQMIHVLLGPN
                     GAGKSTCINMLSGDLPPSEGRIHYLGKDITALTAAQRSQVGIGRSYQRTNIFPQFTVL
                     ENVRLAAQSRRQQPWSLFTKAMEQKWALEKARACIDEAGLGKRVDWVSGVLSHGEQRQ
                     LEIAMVLATDAQVLLLDEPLAGMGSEESASMVEVLKRLRQTRGILLVEHDMDAVFAVA
                     DMITVMVNGQLLECGPPAQIKASVAVQQAYLGTEDSFHV"
     gene            complement(1422..2387)
                     /locus_tag="P5537_06215"
     CDS             complement(1422..2387)
                     /locus_tag="P5537_06215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HRV77674.1"
                     /translation="MNANASLIPKLVALAIVACVPLSGESFYIEIVGKVLVMAIFAMS
                     LDLLVGFTGLVSFGHAAYFGIAAYAVAILSPEYEAASLWYVLPASVGLSALAAFVIGL
                     FVLRTKGIYFIMVTLAFAQMAYFIFHDTPLGGGSDGKYLNNKPSASIFGWEPFDLTNE
                     VHMFYFVLAVLVLVYLFLARVLQSPFGRVLVGIKSNEHRMQSLGYLTFRYKLGAFTLA
                     GALGGLAGFLYAVLFGFVTPELLSWHESGNVLLMVILGGMGNLAGAIAGAFAFEAMRE
                     IFADITKYWQLLMGGVIVAVVLFLPGGLAGVPGRIKRALQGGEAK"
     gene            complement(2392..3258)
                     /locus_tag="P5537_06220"
     CDS             complement(2392..3258)
                     /locus_tag="P5537_06220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HRV77675.1"
                     /translation="MDFASFLIQTLNSLQYGLLLFLVASGLTLVFGIMGIINLAHGSF
                     YMIGAYLAFVLTSATGSLVLAIVLGIPLALAFGAFLEWALFSHLYKRDHLEQVLLTYG
                     LILIFEQLRSLLVGDDVHGVAIPAFLDASIQLTEVMSYPVYRLAISVICIVLAVALYY
                     VIQRTRLGMMIRAGNDDRGMVEALGININMIYRVVFALGVALAALAGMLAAPISSVFP
                     NMGSHVLIISFVIVVIGGIGSVWGALVAALIVGFADTFGKVLVPELSGIVVYVVMAVV
                     LLWRPEGILKKG"
     gene            complement(3365..4537)
                     /locus_tag="P5537_06225"
     CDS             complement(3365..4537)
                     /locus_tag="P5537_06225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004265875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HRV77676.1"
                     /translation="MKNTFKLAGNLALTLALAAAGIGAANAADKVKVGLMLPYTGTYA
                     ALGTAITNGFKQFVDENGGKLGGREVEYFTVDDESNPAKATENAKKLVSRDKVDVLVG
                     TVHSGVALAMAKVARDTKTLMIVPNAGANDLTGPLCSPYVFRSSFSAWQPSYAMGEAL
                     AKKGVKSVATVTWKYSFGEESVAGFKEAFEKGGGKLVKEMTLPFPNVEFQPFLTEIAS
                     AKPDAVFVFFAGAGAAKFVSDYAAAGLKNSIPLYGPGFLTDGNLGAMGGAGEGLLTTL
                     HYADGLTNAKDAAFRTKYAQTYKLQPDVYAVQGYDAAQMYEAGLKAAGGDPEKKDDVI
                     KGMESAKIDSPRGAFTLSKAHNPVQDIYMRQVKGDQNVMLEVVSKGLEDPARGCKM"
     gene            complement(4692..5480)
                     /gene="dmpH"
                     /locus_tag="P5537_06230"
     CDS             complement(4692..5480)
                     /gene="dmpH"
                     /locus_tag="P5537_06230"
                     /EC_number="4.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047437 - 4-oxalocrotonate decarboxylase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo-3-hexenedioate decarboxylase"
                     /protein_id="HRV77677.1"
                     /translation="MKLNQQTIEQLAEHLENAELQAFEVVKITEAHPDMDWDDAYAIQ
                     AEILRRKLARGNRVVGLKAGLTSRGKMKQMGVDTPVFGWLVDYFSVPDGGEIKTSELI
                     HPKVEPEIVFVTKRALKGPGCHIGAVLAATDFVMPGIEIIDSRYKDFKFDLKSVIADN
                     CSSTRFVLGGQAAPVAGLDLRTLGVVLEKNGEPVAVGAGAAVLGHPAAAIAALANHLG
                     ARGEEIPAGTMILSGGVTEAVAVQAGDSVNLRIQSLGSVSTRFI"
     gene            complement(5522..6304)
                     /gene="dmpE"
                     /locus_tag="P5537_06235"
     CDS             complement(5522..6304)
                     /gene="dmpE"
                     /locus_tag="P5537_06235"
                     /EC_number="4.2.1.80"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004265883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxopent-4-enoate hydratase"
                     /protein_id="HRV77678.1"
                     /translation="MDQKTIEALGDSLYDALVARTPIAPLSAAHPDMTIEDAYHVQQR
                     MIARRLEKGDRVIGKKIGVTSKAVMNMLGVHQPDFGYLLDSMVFNEGESVDMDTLIQP
                     KAEGEIAFLLKKDLQGPGVTAADVLAATEGVMACFEIVDSRIQDWKIKIQDTVADNAS
                     CGVFVLGDQLVDIADLDLALAGMVLEKNGEIVVTGAGAATMAHPVNAMVWLANMLGSL
                     GIALKAGDIVLSGAMGAMVPVARGDNLRMTIGGIGGCSVRFV"
     gene            complement(6319..7779)
                     /locus_tag="P5537_06240"
     CDS             complement(6319..7779)
                     /locus_tag="P5537_06240"
                     /EC_number="1.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004265886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxymuconic semialdehyde dehydrogenase"
                     /protein_id="HRV77679.1"
                     /translation="MITDKILNFIDGEYVATDKWYENRNPINNKVIGMVAEAGEKEVD
                     AAVKAAKAALKGPWGSMSLQKRIELLEALVVEINNRFDDFLEAECADTGKPKSMASHV
                     DIPRGAANFKVFADMVKNVPTEFFEMSTPDGGKAINYGYRRPVGVVGVICPWNLPLLL
                     MTWKVGPALACGNTVVVKPSEDTPRTAALLGEVMNKVGIPKGVYNVVNGFGANSAGAF
                     LTAHPDVDALTFTGETRTGEVIMKAAANGSRPVSLEMGGKNASIVFADCDFDKAIEGT
                     LRSVFLNCGQVCLGTERVYVERPIFDKFVAALKAGAEGMKIGVPDDPAANFGPLVSKK
                     HQEKVLSYYKVAVEEGATVVTGGGVPDMAGELADGCWVQPTIWTGLPETARVIKEEIF
                     GPCCHIAPFDTEDEVLEKANDNKYGLACAIWTQDVSRAHRVAQKMEVGISWVNSWFLR
                     DLRTPFGGSKQSGIGREGGVHSLEFYTDLKNVCIKL"
     gene            complement(7923..8852)
                     /locus_tag="P5537_06245"
     CDS             complement(7923..8852)
                     /locus_tag="P5537_06245"
                     /EC_number="1.13.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018577 - catechol 2,3-dioxygenase
                     activity [Evidence IEA];
                     GO_process: GO:0009712 - catechol-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catechol 2,3-dioxygenase"
                     /protein_id="HRV77680.1"
                     /translation="MATTGVMRPGHIQLRVLDLDESVAFYKDVVGLVETGRDAAGRVY
                     FKAWDERDHNSVILRQADRAGVDLIGFKVKDKATLEQLDKDLQAYGVATERIPAGELL
                     ETGERVRFTIPTGHVMELYAEKTDVGNGQPYTNPDPWIAASEHGIAPHRFDHCLLYGP
                     NLEENLKLFTEVLGFHLVERVLLEDGKSLLATFISCSHKAHDLAFVAHPEPGKLHHLS
                     FLLDSWEKVLRAADIMSMNRVSIDIGPTRHGITRGSTIYAFDPSGNRFETFCGGYETY
                     PDHAPITWTFDEVGAGIFYHDRKLNERFLTVVT"
     gene            complement(8950..9309)
                     /locus_tag="P5537_06250"
     CDS             complement(8950..9309)
                     /locus_tag="P5537_06250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004265891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /protein_id="HRV77681.1"
                     /translation="MNTPAPKVFHQVTIVETGEVYRCREDETLLAGMERLGKRGIPVG
                     CRGGGCGVCKVQVEAGEYSKRVMSRAYVSAEEEAAGIVLACRVKPLSDIRLAVLGKMK
                     KNVCATPSAAAADARQS"
     gene            complement(9311..12853)
                     /locus_tag="P5537_06255"
     CDS             complement(9311..12853)
                     /locus_tag="P5537_06255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase family
                     protein"
                     /protein_id="HRV77682.1"
                     /translation="MSSGKQISNTFTQEEGDIHLGGIDAIVRLTLDQVRTDARRGLKT
                     GMFVSGYRGSPVGMLDAALIKQQKLLVQNHIHFVDGINEDLAATAVWGTQMLHTVGKQ
                     KFDGVTGMWYGKAPGVDRSGDALKHANYTGIAKNGGVLAIAGDDPSCKSSSLCSQSEP
                     MLFHVGIPSLYPGNVQEILDYGLHGYQMSRLGGLWVGMKIVTNVADGTGTASVSPERL
                     NFVTPDLEFDGKLFTPNMNLGMNVRVEALEMEQSLYTRRLEVAKRYARANNLNNVVFP
                     NPDAWIGIITAGKTYNDLNQAFLEMGLDDAALRRYGIRILKMGMLFPMEPTIVREFAQ
                     GLEEIFVIEEKRPFLEMFAKQVLYGMANAPRIVGKFDEEEKELLPHYGEFESDVIVRA
                     LLKRLSRKTRIESAENWLKRLDEIHSRNKLPTAVRTAWFCSGCPHNSSTQAPDGSIVS
                     AGIGCHTMAMWMGRNVVMGTHMGAEGTQWIGMAPFTEAQHIFQNMGDGTYAHSGSLAI
                     RYAASTGVNITFKLLRNAHTSMTGGQAIQGEVPVTNMVSDLLANGVKKIIVTTDDPSR
                     FNGVQLPGGTEVWHRDRLDEAQKVLAATPGCTVLLHDQECAAELRRARSRGKADEPVE
                     VTVINERVCEGCGDCGEKSNCMSVEPVQTEFGRKTRIHQSSCNKDFSCVKGFCPSFLT
                     ITPHPAPAADGAPKKKKGRIPALERELPAPVNKVDDSLGFGIHVMGIGGTGSVTVVAT
                     LARAARLEGKHVIGLDQTGLAQKGGAVISDIKITHAPFKGSNKISDGRADLYLGFDIL
                     NATDPKNLDKCNPERTIAVVSTTQTPTGQMVTNRKALFPATSGLTGGIDRVTRKEHNV
                     FLDGEALAAGLFGDAMATNNFMVGVAFQAGTIPLKAESIEEAIRLSGVAVDMSLAAFR
                     WGRMAVVDRAFVEAEVARQKSGGQVVVLNMAPQLTPAARAIVDSIGADGEVKRLVEIR
                     VPELIAFQDEAYAKRYAEVVKRVVAGEQKAVSSSRLAEAAARYLYKLMAYKDEFEVAR
                     LHTDPAFLAELEAQFPHGYSVKYNLAPPLLAKTDPVTGHPQKKQYGEWMFKAFKRLAG
                     LKRFRGSSLDVFAKTEERRTERQLIEEYIQLLDQILARLNPVNHAAAVALASVPDEIR
                     GFGHVKEKNLAAARELQAARLKAFNEAQQERQVA"
     gene            13127..14467
                     /gene="benA"
                     /locus_tag="P5537_06260"
     CDS             13127..14467
                     /gene="benA"
                     /locus_tag="P5537_06260"
                     /EC_number="1.14.12.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004265895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate 1,2-dioxygenase large subunit"
                     /protein_id="HRV77683.1"
                     /translation="MITTEYLDSLIEKDKEKGLFRCKREMFTSSELFDLEMKHIFEGN
                     WIYLAHESQLPKINDYYTTKIGRQPVFITRNKDNQLNCFINACAHRGATLARFKHGNK
                     ATYTCPFHGWTFNNSGKLLKIKDPTETGYPEGFNCEGSHDLKKIARFESYRGFLFGSL
                     NPDVQSLEDYLGESKKIIDMIVDQSPEGLEVLRGSSTYVYEGNWKLQAENGADGYHVT
                     AVHWNYAATQAQRKSRDAGDDIKAMSAGGWAKKGGGSYSFENGHLLLWTRWDNPEDRP
                     LMEQRDRLVGEFGEAKADWMIGNSRNLCLYPNVYLMDQFSSQIRVFRPLSVDRTEVTI
                     YCIAPKGESAEARARRIRQYEDFFNASGMATPDDLEEFRACQEGFMGRALEWNDMSRG
                     ATHWVEGPDDEADKIGLKPILSGVKTEDEGLYVAQHTYWLEQIRKAAEAEAKNA"
     gene            14483..14971
                     /gene="benB"
                     /locus_tag="P5537_06265"
     CDS             14483..14971
                     /gene="benB"
                     /locus_tag="P5537_06265"
                     /EC_number="1.14.12.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006725 - cellular aromatic compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate 1,2-dioxygenase small subunit"
                     /protein_id="HRV77684.1"
                     /translation="MSISYENLCAFLYREARHLDDREWDEWLAMYDENCTFWMPAWDD
                     DGELTEDPQSEISLIWYGRRSGLEDRVFRIRTERSSATIPDTRTNHHISNIEVVEQND
                     KTVKLRFNWHTMSVRYNHTDHFCGTSFYTLDVSGASPLIKEKKVVLKTDYIRHVIDVY
                     HV"
     gene            15041..16051
                     /gene="benC"
                     /locus_tag="P5537_06270"
     CDS             15041..16051
                     /gene="benC"
                     /locus_tag="P5537_06270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate 1,2-dioxygenase electron transfer
                     component BenC"
                     /protein_id="HRV77685.1"
                     /translation="MTFKIALNFEDGVTRFIECNATETVADAAYRQGVNVPIDCRDGA
                     CGACKCKAESGKYELGFYIDDAMSEEEAKLGYVLTCQMHPKSDCVVNVPASSEVCKIK
                     HATLTATVAEVRQLSPSTLSLVLQGEGVGKLAFLPGQYANLTVPGTEQTRAYSFSSMP
                     ADSKVSFLIRNVPNGLMSGYLTGAAKPGDTIKLAGPIGSFYLRDVARPVLMLAGGTGL
                     APFLAMLDKLVAAGGSAHPIHLIYGVNTDADVVELERLDAFQAALPNFSYDVCVVADD
                     SSWPKKGYVTAHIEPAHLNEGKVDIYLCGPPPMVEAVAHDLRERKVEPNSFHYEKFAA
                     SV"
     gene            16079..16855
                     /locus_tag="P5537_06275"
     CDS             16079..16855
                     /locus_tag="P5537_06275"
                     /EC_number="1.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004265908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate
                     dehydrogenase"
                     /protein_id="HRV77686.1"
                     /translation="MANRFKKKVAVITGAAQGIGKRVAEKMAKEKGTLVLVDRSELVH
                     EVAKELSAKVEVLSLTADLEKFADCKRVMEAAVEKFGRIDILINNVGGTIWTKPFEHY
                     GEDEIEAEVRRSLFPTLWCCRAALPYMQEQGKGAIVNVSSIATRGVNRVPYGAAKGGV
                     NALTACLALENGERGIRVNATAPGATEAPPRLIPRNTKEQSEQEKLWYKQIYTQSIDS
                     SLMKRYGTLDEQADPILFLASDDSAYITGTIVPVGGGDLG"
     gene            17163..18134
                     /locus_tag="P5537_06280"
     CDS             17163..18134
                     /locus_tag="P5537_06280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HRV77687.1"
                     /translation="MSIRFLNGQSNVFAAANPFEVSEYVRANVGSHSLRLPRASDASA
                     SLSHRRAGTLDLCRLSYGAQARVLSESLGDIYHAQFILQGYCSYTLANRTLDLPAGHV
                     LVLNPDEPVDLTYSDNCEKFIVRIPSSMLDDACAEHRWFKPNERIKFSPEPQRFEDID
                     SLLLLLRLLCEEAESELATPQMLQHYCRVVTTKLMVMLKHNVSMVAPSRHAPSFERLV
                     NYIERNIKLELGADELAQYAGLSLRSLYLLFEKNVKTTPKNFVRQKKLEKVHSILNDP
                     AQACPNVTAVALEYGFSHLGRFSELYKSTYGVLPSQSIRCRQPQAGR"
     gene            18239..18637
                     /locus_tag="P5537_06285"
     CDS             18239..18637
                     /locus_tag="P5537_06285"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HRV77688.1"
                     /translation="MERTAINPPELFSGKAFSQTFSISTPQRLIFVSGQVDCDREGKV
                     RNPDDLEAQLKGTLDNLEIALRAQGASMRDLVQVTIYVVGLRPEDTTRIREIRSAYFD
                     TERPPAVTLLGIERLAFPGLRVEIDIIAAQ"
     gene            complement(18743..19321)
                     /locus_tag="P5537_06290"
     CDS             complement(18743..19321)
                     /locus_tag="P5537_06290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004265913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HRV77689.1"
                     /translation="MNAPAAAPAAAPARVTRIARRRARPGHEAEYEGMLREMLAKMRE
                     HKGFLGGDLIPPEAPGEEYQLVVRFASEAELQAWDMSDARGALLERMKAVAEGEPEFR
                     KLSGLEAWFEPAVVPATMHPPRARMALVTWLGIFPTVSFFLWFVLPWIQPLPFLPRTA
                     VLTALIVVTMTWVVMPRLTRVLRGFLNPPRKG"
     gene            complement(19538..20455)
                     /locus_tag="P5537_06295"
     CDS             complement(19538..20455)
                     /locus_tag="P5537_06295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HRV77690.1"
                     /translation="MKISKIAAAVALGALAIGGAHAKDGGDQYPNGAETWLGGAVPPP
                     GNYFINYFGYYGGELRDGDGNKAPSGEVDAWFNAFRFVHTSEHKILGGNWGWHVIVPL
                     VHQKVDLFGSKSVNGVGDITIDPFIVSWHSKNWHWAIGLDINLPTGRYKEGDARQSIG
                     ANYWSYEPLFAFTYMGDTGWEVSAKLMYNIKTKNKDYDGPAGVGSYASGDEFHMDYLV
                     GKRIGPWGVGLSGYYLKQTTDDEINGQKVAANAFWSEGRRGQVFAIGPTVSYTTKGGV
                     HLTAQWNHETKVENRFEGDKFVVKLIMPL"
     gene            complement(20558..20827)
                     /locus_tag="P5537_06300"
     CDS             complement(20558..20827)
                     /locus_tag="P5537_06300"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: protein motif:HMM:NF025903.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016862 - intramolecular oxidoreductase
                     activity, interconverting keto- and enol-groups [Evidence
                     IEA];
                     GO_process: GO:0006725 - cellular aromatic compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxymuconate tautomerase"
                     /protein_id="HRV77691.1"
                     /translation="MGAECNAAASCHRAGRHRFDDKEGQSMPLAEITMIEGRTEDQKR
                     AVIEKVTQALVEAVGAPIQTVRVVIREVPKTNWGIGGVSAKDLGR"
     gene            complement(20873..21904)
                     /gene="dmpG"
                     /locus_tag="P5537_06305"
     CDS             complement(20873..21904)
                     /gene="dmpG"
                     /locus_tag="P5537_06305"
                     /EC_number="4.1.3.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008701 - 4-hydroxy-2-oxovalerate aldolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-2-oxovalerate aldolase"
                     /protein_id="HRV77692.1"
                     /translation="MELRGKKITVHDMTLRDGMHPKRHLMTLEQMKTIATGLDEAGVP
                     LIEVTHGDGLGGASVNYGFPAHSDEEYLGAVIPLMKQAKVSALLLPGIGTVDHLKMAH
                     ELGVSTIRVATHCTEADVSEQHIGMARKLGMDTVGFLMMAHMNSPEGLVKQAKLMEGY
                     GANCIYVTDSAGHLLPDTVKARLAAVRDALKPETELGFHGHHNLAMGVANSLAALEVG
                     ATRIDAAAAGLGAGAGNTPLEVFIAVCDLMGIETGVDVFKIQDVAEDLVVPIMDFPIR
                     IDRDALTLGYAGVYGSFLLFAKRAEKKYGVPAREILVEMGRRGMVGGQEDMIEDTALN
                     LARAKGLAA"
     gene            complement(21930..22853)
                     /locus_tag="P5537_06310"
     CDS             complement(21930..22853)
                     /locus_tag="P5537_06310"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004265933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008774 - acetaldehyde dehydrogenase
                     (acetylating) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="HRV77693.1"
                     /translation="MNKIKCALIGPGNIGTDLLYKLKRSPVLEPVWMVGIDAGSEGLV
                     RARELGLKTTADGVDGLLPHVKADGVQIAFDATSAYVHAENSRKLNELGVLMIDLTPA
                     AIGPFCVPPVNLAEHVGKGEMNVNMVTCGGQATIPMVAAVSRVQPVAYGEIVATVSSK
                     SAGPGTRKNIDEFTRTTAGAVEKVGGAKKGKAIIILNPAEPPLIMRDTVHCLTETEPD
                     REKITASIHAMIQEVQKYVPGYRLVNGPVFDGNRVSVFLEVEGLGDYLPKYAGNLDIM
                     TAAGARTAEMFAEEIIKGRLKLESNRATMVA"
     gene            complement(22993..23430)
                     /locus_tag="P5537_06315"
     CDS             complement(22993..23430)
                     /locus_tag="P5537_06315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HRV77694.1"
                     /translation="MKVAVPQATISWEAAHAAVAAAVEKAEALGVRINVAVADASGNL
                     VAFLRMPGAFPQSIAIAIDKAYTAGGFGFPTGKWMDVCAGNEGMKLGFSAQPRLVVFG
                     GGLPIRVGGELVGGIGVSGASEEQDGVCARAGLLAIGADDVES"
     gene            23591..24310
                     /locus_tag="P5537_06320"
     CDS             23591..24310
                     /locus_tag="P5537_06320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004265939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FCD domain-containing protein"
                     /protein_id="HRV77695.1"
                     /translation="MNEAVPPRTPEAVEPKTLVEGAYQRLRRDIIEGVHPPGEKLRVE
                     HLKDRYEVGAGTLREALLLLVTDALVVAQGQRGFRVSPISIEDFEDITRTRLLLETEA
                     LRQSLQLGGEDWEAAIVAAFHRLSRAEQKLGDNDSLAAEEWERRNRAFHEALIAASPS
                     RWIRHFQHILYQQSERYRRLSLFSHPIPRDIHAEHQALFNACLARDTTRATSILTEHV
                     LRTLDAVKLLPAEFFAGKRKS"
     gene            complement(24437..25366)
                     /locus_tag="P5537_06325"
     CDS             complement(24437..25366)
                     /locus_tag="P5537_06325"
                     /EC_number="1.13.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018577 - catechol 2,3-dioxygenase
                     activity [Evidence IEA];
                     GO_process: GO:0009712 - catechol-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catechol 2,3-dioxygenase"
                     /protein_id="HRV77696.1"
                     /translation="MAMTGVLRPGHISLRVLDLEEGINFYKNTLGLVETGRDSQGRVY
                     FKAWDEREHNSVLIREAESAGVDFFAFKVADRATLDKLDADLQAFGVKTERIPAGEML
                     ETGERVRFEVPSGHLIELYAEKTDIGNGQSYVNPDPWIPDAEHGIAPSRMDHCLLYGP
                     DIEKVQEIFEKVLGFYLVEHVVMEDGKTDLAIWLSCSTKAHDIAFVRHPEPGKLHHIS
                     FKLDSWEKVLRAADIMSMNRISIDIGPTRHGITRGTTIYAFDPSGNRFETFCGGYDTY
                     PDYKTITWTWDEVGAGIFYHDRKLNERFLSVVS"
     gene            complement(25509..26384)
                     /locus_tag="P5537_06330"
     CDS             complement(25509..26384)
                     /locus_tag="P5537_06330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HRV77697.1"
                     /translation="MGTTATAQPSAPASAAGDPEIGRSIRAAGILTNYHDLGEGFPAL
                     FIHGSGPGVSAWANWRLVLAPLSQRMRVIAPDMAGFGFTERRADIRYDMDTWVAQALG
                     LMDALGIEQADVVGNSFGGALALALAIRHPQRVRRLVLMGSVGVPFPITAGLDAVWGY
                     TPSFENMRRIMDYFAWDRSLVNDELAELRYRASVRPGFQESFASMFPAPRQRWVDALA
                     SREQDIRALPHEALIIHGRDDRVIPLQTSETLLRWIERSQLHVFGRCGHWTQIEHSAR
                     FVRLVGDFLCEEGEG"
     gene            complement(26404..27459)
                     /locus_tag="P5537_06335"
     CDS             complement(26404..27459)
                     /locus_tag="P5537_06335"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenol 2-monooxygenase domain-containing
                     protein"
                     /protein_id="HRV77698.1"
                     /translation="MSYELTIEPIGQTIEVEEGQTILDAALRAGIWLPHACCHGLCAT
                     CKVQVLDGEIDHGEASSFALMDFERDEGKTLACCARLESDVTIEAEIEEDPDAESIPV
                     RDFPGTVTRIEALTPTIKAVFIETDEPMHFQAGQYVNFFLEGGEYSRAFSLANPPSTG
                     REVELNIRIVPGGRGTTWIHEQLRVGERVRLSGPYGRFFVRKSAPEALLFMAGGSGLS
                     SPRSMILDLLEAGDTRPMTLVYGQRNRAELYYHDEFLALAAKHPNFTYVPALSDEPAD
                     SGWDGFRGYVHEAATAHFDNDFRGHKAYLCGPPLMIDACITALMQGRLFERDIFMEKF
                     FSAADVQQVRSPLFKKI"
     gene            complement(27535..27894)
                     /locus_tag="P5537_06340"
     CDS             complement(27535..27894)
                     /locus_tag="P5537_06340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenol hydroxylase subunit P4"
                     /protein_id="HRV77699.1"
                     /translation="MAVAAISKYEFAPTDTQDKFHGAQLLYIGWEDHLLFCAPFAFPF
                     PPTMRFGDVVAGPMQAAFGYHPDFAQIDWAKAEWFKSGKPVTLDFDKSLAENGLKHKD
                     VIRFRTPGLAGIKGSCS"
     gene            complement(27957..29510)
                     /locus_tag="P5537_06345"
     CDS             complement(27957..29510)
                     /locus_tag="P5537_06345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004265985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic/alkene/methane monooxygenase
                     hydroxylase/oxygenase subunit alpha"
                     /protein_id="HRV77700.1"
                     /translation="MDMQVAKKKLGLKERYAVMTRGLDWTPSYQKMEDIYPYIAYEGI
                     KIHDWDKWEDPFRLTMDAYWKYQAEKERKLYAIIDAFNQNNGHLNVTDARYVNTVKLF
                     ISGISPLEYVAHRGFAHAGRAFPGPGPRVACLMQSLDEIRHAQTQVHSISNYNKYYNG
                     MHDFHHMHDRVWFLSVPKSFFDDAITAGPFEFMVSIGFSFEYVLTNLLFVPFVSGAAY
                     NGDMGTMTFGFSAQSDEARHMTLGLEVIKFILEQDPANVPIVQRWIDKWTWRGYRVLT
                     LVAMMMDYMLPKRTMSWKEAWEVYFEENGGALFKDLARYGITMPKCAEQIALEKDHLS
                     HQAWSTFYNYAAAANFHTWMPDEDEMAWLSSKYPESFDKLYRPRYEFWREQAAKGNRF
                     YNKTLPMLCQTCQIPMIFTEPGDATKICYREVDYKGDKYHFCSDHCKEIFEHEPEKYV
                     QAWLPVHQIYQGNCFPEGTDPTVEGFDPLAAVLKYYNLEHGRDNLDFDISEDKKNFAE
                     WRGQATKNI"
     gene            complement(29531..29800)
                     /locus_tag="P5537_06350"
     CDS             complement(29531..29800)
                     /locus_tag="P5537_06350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmoB/DmpM family protein"
                     /protein_id="HRV77701.1"
                     /translation="MSTVFLALQTNEDTRPIIEAILQDNPSAVVDEQPAMVKINADGR
                     LVVRRETIEELIGRDYDLQELQVNMITMSGNLDQTDDEITLFWKS"
     gene            complement(29813..30808)
                     /locus_tag="P5537_06355"
     CDS             complement(29813..30808)
                     /locus_tag="P5537_06355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002932128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic/alkene monooxygenase hydroxylase
                     subunit beta"
                     /protein_id="HRV77702.1"
                     /translation="MQIDLRTVTIKPLRQTFDNIARRIGADKPASRYQEGTLDMQQTA
                     NFHYRPTWDPAHDIYDASRTAIKMADWYAFKDPRQFYYGAYTLARAKQQDTAEANFDF
                     VENRGLAATLPESVRKTVLELLLPLRHVAWGSNMNNASVCAYSYGTGFSQPHIYQAMD
                     QLGIAQYLTRVGLLLGDVESLDEAKRAWMDDDAWQGLRRYVEDSFVIKDPVELFVAQN
                     VALDGLLYPLVYETIIDDVLSSQGGTPVAMLTQFMTDWFTETRKWVDATVKIAAAESP
                     ENKEVMARWLSQWRDRSAAALLPVARIALGDRSDEVVGEVVQQFNARMAKAGVAL"
     gene            complement(30842..31111)
                     /locus_tag="P5537_06360"
     CDS             complement(30842..31111)
                     /locus_tag="P5537_06360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenol hydroxylase subunit"
                     /protein_id="HRV77703.1"
                     /translation="MKNTEPAVDLNRKFVRLIERRPDGFVEFEFAIGDPELFAEMLLP
                     SDAYESFCQSNHVVFLDPREEAAKDEDEAGDWNWTLHQATHQRFR"
     gene            31595..33268
                     /locus_tag="P5537_06365"
     CDS             31595..33268
                     /locus_tag="P5537_06365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HRV77704.1"
                     /translation="MASIQYPENADLRSLLRFAAEDGLIWLGEHRMLLLHAGAMAELR
                     KELIESVGREQARRILTRMGFASGMRDAELARKTRSGSDLADAFVMGPQLHMLEGCAR
                     VEPVRLEFGGPDNGFYAEFLWENAWEAEAHVQAFGESTEPVCWMMIGYASGYTSAFTG
                     RFILFRETECAATGHERCRIVGRPAEDWPDVDSLLPYFQADSIVGRLLELREEIEAMR
                     RTIAGPHRTPDLIGSSTAFLHAYDLIGRAAATNVSVLLLGETGVGKERFARTLHEMSA
                     RKDEAFVAVNCAALPDELIESELFGVERGAFTGAHASRAGKFERAHGGTLFLDEVGEL
                     PLPAQAKLLRALQEGEIERLGDERTRKVNVRLVAATNVDLQKAVNAGTFRRDLYYRLN
                     VYPVTIPPLRERTGDIPALVEAMVRRFETLHGKHIAGLSDKAMRALKLHTWPGNVREL
                     ENVLERGVILAPPNGQIEVEHLFIATFDEHAREHSLSAQGGLEAAQREQQDLATAVLD
                     SGISLDAFEQRLLQHAVERANGNLSAAARLLGMTRPQLNYRIKKQGAGG"
BASE COUNT         5541 a        11102 c        11041 g         5754 t
ORIGIN      
        1 gtgccgtcga acacgacctg ccccttgacc aggatcatcg cgcggtcgca gatgctggtg
       61 accgcgccgt ggttcttgtc cacgatcacg gtggcgatgc cggtcctgcg gatctccttg
      121 acgatgcgcc agatctccat cgcgatcagc ggcgcgagac cttccgtggc ctcgtccagg
      181 atcagcaggt cggggttggt catcagcgcg cggccgatgg tgagcatctg ctgctcgccg
      241 cccgagagct gccagccgcc gttgttgatg cgttcgccca ggcgcgggaa ggtctccatg
      301 acccggtcga aggtccactc gcggcgacca tcgacgccgg cgcgcgccga catcagcagg
      361 ttctcgcgca ccgtcaggct cttgaagatg ccacgccctt ccggcacgta ggcgatgccc
      421 tgctgcgcgg tctggaaggt acgtgccctg gtgtagtcgt cgccgcgcac gagcacgcgc
      481 ccgtgccgcg gacggacgat gccgagcatg ctcttgatca gcgtcgactt gcccatgccg
      541 ttgcggccca tgagggcgat gccctcgcct tcgcggatgt tgaagtcgat gccgtgcagg
      601 atgtggctcg caccgtagta ggtatgaatt tccttgcctt cgagcagcat gttagacatg
      661 gaagctgtcc tccgtaccca ggtaggcctg ctggacggcc acgctggcct tgatctgcgc
      721 gggcggcccg cactccagca actgcccgtt gaccatcacc gtgatcatgt cggcgaccgc
      781 gaacaccgca tccatgtcgt gctccacgag caggatgccg cgcgtctggc gcaggcgctt
      841 gagcacctcg accatgctcg cggactcctc cgagcccatg ccggcgagcg gctcgtcgag
      901 cagcagcacc tgtgcgtcgg tggcgagcac catggcgatc tcgagctggc gctgttcgcc
      961 gtggctgagc acgcccgaca cccagtcgac gcgcttgccc aggccggcct cgtcgatgca
     1021 ggcgcgtgcc ttctccagcg cccacttctg ctccatggcc ttggtgaaca ggctccacgg
     1081 ctgctggcgg cgcgactgcg cggccaggcg cacgttctcc agcacggtga actgcgggaa
     1141 gatgttggtg cgctggtagc tgcgcccgat gcctacctgc gatcgctgcg ccgcggtgag
     1201 cgcggtgatg tccttgccga ggtagtggat cctgccctcg gacggcggca ggtcgcccga
     1261 cagcatgttg atgcaggtcg acttgccggc gccgttgggg ccgagcagca cgtggatcat
     1321 ctggcgctcg agggtcacgc tgatgtcctg gttcgccacc aggccgccga agcggcgggt
     1381 gagcttgtcg gcctgcagca ggacttcgtt cttcgtcgtg ctcatttggc ttctcccccc
     1441 tgcagggcgc gcttgatgcg gcccggaacg ccggccagcc cgcccggcag gaacagcacg
     1501 accgcgacga tcacgccgcc catcagcagc tgccagtact tggtgatgtc ggcgaagatc
     1561 tcgcgcatcg cctcgaaggc gaaggccccg gcgatcgcgc cggcgaggtt gcccatgcca
     1621 cccaggatca ccatcagcag cacgttgccc gactcgtgcc aggacagcag ctcgggggtc
     1681 acgaagccga acagcacggc gtagaggaag cccgccagcc cgccgagcgc gccggccagc
     1741 gtgaaggcgc cgagcttgta gcggaaggtg aggtagccga gcgactgcat gcggtgctcg
     1801 ttgctcttga tgcccaccag cacgcggccg aagggcgact gcagcacacg ggcgaggaac
     1861 aggtacacca gcaccagcac ggcgagcacg aagtagaaca tgtgcacttc gttggtgagg
     1921 tcgaacggtt cccagccgaa gatcgaggcc gacggcttgt tgttgaggta cttgccgtcc
     1981 gagccgccgc cgagcggggt atcgtgaaag atgaagtagg ccatctgcgc gaaggccagc
     2041 gtcaccatga tgaagtagat gcccttggtg cgcagcacga acaggccgat gacgaaggcg
     2101 gcgagcgcgg acaggccgac cgacgccggc agcacgtacc acaggctggc cgcctcgtac
     2161 tcggggctca ggatcgccac cgcgtaggcg gcgatgccga agtaggccgc gtggccgaag
     2221 ctgaccaggc cggtgaagcc caccagcagg tccaggctca tggcgaagat cgccatcacc
     2281 agcaccttgc cgacgatctc gatgtagaag gactcgcccg acagcggcac gcaggccacg
     2341 atcgcgagcg cgaccagctt gggaatcagg gaagcgtttg cgttcatggt ctcagccctt
     2401 cttcaggatg ccttcggggc gccacagcag gaccaccgcc atgaccacat acaccacgat
     2461 gccggagagc tcggggacca gcaccttgcc gaaggtgtcg gcgaagccga cgatcagcgc
     2521 ggcgacgagc gcaccccaca ccgagccgat gccgccgatg accacgatca cgaacgagat
     2581 gatcagcacg tggctgccca tgttcgggaa caccgacgag atcggcgcgg cgagcatgcc
     2641 ggcgagcgcg gcgagcgcga caccgagcgc gaacacgacg cggtagatca tgttgatgtt
     2701 gatgccgagc gcctcgacca tgccgcggtc gtcgttgccg gcacggatca tcatgcccag
     2761 gcgggtgcgc tggatgacgt agtagagcgc gaccgcgagc acgatgcaga tcaccgagat
     2821 ggccagccgg tacaccggat agctcatgac ctcggtgagc tggatcgagg cgtcgaggaa
     2881 ggccgggatc gccaccccgt gaacgtcgtc accgacgagc aggctgcgca gctgctcgaa
     2941 gatgaggatg aggccgtagg tcagcagcac ctgctcgagg tggtcgcgct tgtacaggtg
     3001 ggagaacagc gcccactcca ggaaggcgcc gaaggccagc gccagcggga tgccgagcac
     3061 gatggccagc accaggctgc cggtcgcgct ggtgagcacg aaggcgaggt aggcgccgat
     3121 catgtagaaa ctgccgtgcg ccaggttgat gatgcccatg atgccgaaca ccagcgtcag
     3181 tccgcttgcc acgagaaaca gcagcaatcc gtactgcagc gagttcagcg tctggatcag
     3241 aaagcttgcg aaatccatga cactccccct cccggcaggc gtgcgcctgt caggatcgat
     3301 cagggttcaa gaagaaacgg gacttggggg cgacccgccg ggccgcccct gcgaggccgg
     3361 gggcttacat cttgcagccg cgggcgggat cctcgaggcc cttggagacg acctcgagca
     3421 tcacgttctg gtcacccttg acctggcgca tgtagatgtc ctgcaccggg ttgtgcgcct
     3481 tggacagggt gaaggcgccg cgcgggctgt cgatcttggc ggactccatg cccttgatga
     3541 cgtcgtcctt cttctccgga tcgccgccgg cggccttcag gccggcctcg tacatctgcg
     3601 cggcgtcgta gccctgtacc gcatacacgt cgggctgcag cttgtaggtc tgcgcgtact
     3661 tggtgcggaa ggccgcgtcc ttggcgttgg tgagtccgtc ggcgtaatgc agcgtggtga
     3721 gcaggccctc gcccgcgccg cccatggcgc cgaggttgcc gtcggtgagg aagcccgggc
     3781 cgtacagcgg gatgctgttc ttgaggccgg ccgcggcgta gtcggagacg aacttggccg
     3841 caccggcgcc ggcgaagaac acgaacaccg cgtcgggctt ggccgaggcg atctcggtga
     3901 ggaagggctg gaactcgacg ttggggaaag gcagcgtcat ttccttgacg agcttgccgc
     3961 cgcccttctc gaaggcctcc ttgaagccgg cgaccgactc ctcgccgaag gagtacttcc
     4021 aggtcaccgt ggcgacgctc ttgacgccct tcttcgccag cgcctcgccc atggcgtagg
     4081 acggctgcca ggccgagaag gaggagcgga acacataggg cgagcacagc ggaccggtga
     4141 gatcgttggc gccggcgttg gggacgatca tcagggtctt ggtgtcgcgg gccaccttgg
     4201 ccatggcgag cgcgaccccg gagtgcaccg taccgaccag cacgtcgacc ttgtcgcgcg
     4261 acaccagctt cttggcgttc tcggtcgcct tggccgggtt ggattcgtcg tcgacggtga
     4321 agtattcgac ctcgcggccg ccgagcttgc cgccgttctc atcgacgaac tgcttgaagc
     4381 cgttggtgat cgcggtaccg agcgccgcat aggtgccggt gtagggcagc atcaggccga
     4441 ccttgacctt gtcggccgcg ttggcagcgc cgatgccggc ggcggccagc gcgagggtca
     4501 gggcgaggtt gccagcgagt ttgaacgtgt tcttcatcat gtctcttcct tgaaggtgga
     4561 ttgggttcgt gcgtcttctg gacgacgcat cgtcttgctg cctgggcgcc cgtcggctgc
     4621 acgcgacgcg cctcgacggg acacgaaacg cggccgcccg tgggcgaccg cgaaggaacg
     4681 aggccgcggc ctcagatgaa acgggtgctg acgctgccga gcgactggat gcgcaggttc
     4741 acgctgtcgc cggcctgcac cgcgaccgcc tcggtgacgc cgcccgacag gatcatggtg
     4801 cccgccggga tctcctcgcc gcgcgcgccg aggtggttgg ccagggccgc gatcgccgcc
     4861 gccgggtggc cgagcaccgc ggcgccggca ccgaccgcca ccggctcgcc gttcttctcg
     4921 agcaccacgc ccagggtgcg cagatccagg ccggccaccg gcgcggcctg gccgccgagc
     4981 acgaagcggg tcgacgagca gttgtcggca atcacgctct tgaggtcgaa cttgaagtcc
     5041 ttgtagcgcg aatcgatgat ctcgatgccg ggcatgacga agtcggtcgc cgcgagcacc
     5101 gcgccgatgt ggcagccggg gcccttgagc gcgcgcttgg tcacgaacac gatctcgggc
     5161 tcgaccttcg ggtggatcag ctcgctggtc ttgatctcgc cgccatccgg cacgctgaag
     5221 tagtcgacga gccagccgaa caccggggtg tcgacgccca tctgcttcat cttgccgcgc
     5281 gaggtcaggc cggccttgag gccgaccacg cggttaccgc gcgccagctt gcggcgcagg
     5341 atctcggcct ggatcgcgta ggcgtcgtcc cagtccatgt cgggatgcgc ctcggtgatc
     5401 ttcaccactt cgaaggcctg cagctcggcg ttctcgaggt gttcggcgag ttgttcgatg
     5461 gtttgctgat tcagtttcat tggaagtttc ctgttggatt ggggggcggg gatcgggcgg
     5521 atcagacgaa gcgcaccgag cagccgccga tgccgccgat cgtcatgcgc aggttgtcgc
     5581 cacgcgccac cgggaccatg gcgcccatcg cgccggagag cacgatgtcg ccagccttga
     5641 gggcgatgcc gagcgagccg agcatgttgg ccagccacac catggcgttg accgggtggg
     5701 ccatggtggc cgcaccggcg ccggtgacga cgatctcgcc gttcttctcc agcaccatgc
     5761 cggcgagcgc gaggtcgagg tcggcgatgt cgaccagctg gtcgccgagc acgaacacgc
     5821 cgcacgaggc gttgtcggcc acggtgtcct ggatcttgat cttccagtcc tggatgcgcg
     5881 aatcgacgat ctcgaagcag gccatcacgc cttcggtggc ggcgagcacg tcggccgcgg
     5941 tcacgcccgg gccctgcagg tccttcttga gcaggaaggc gatctcgccc tcggccttgg
     6001 gctgaatgag cgtgtccatg tcgaccgact cgccctcgtt gaagaccatg ctgtcgagca
     6061 gatagccgaa gtcgggctga tgcacgccca gcatgttcat caccgccttg ctggtgacgc
     6121 cgatcttctt gccgatcacg cggtcgccct tctcgaggcg gcgcgcgatc atgcgctgct
     6181 gcacgtggta ggcgtcctcg atcgtcatgt cgggatgcgc tgcgctcagc ggcgcgatcg
     6241 gcgtgcgcgc gacgagcgcg tcgtagagcg aatcgcccag ggcttcgatg gttttctggt
     6301 ccatgtacgg tcttcctatt acagcttgat gcagacgttc ttcaggtcgg tgtagaactc
     6361 gagcgagtgc acaccgccct cgcggccgat gcccgactgc ttggagccac cgaagggggt
     6421 gcgcaggtcg cgcaggaacc agctgttcac ccaggagatg cccacttcca tcttctgcgc
     6481 gacgcggtgc gcgcgcgaga cgtcctgcgt ccagatcgcg caggccaggc cgtacttgtt
     6541 gtcgttggcc ttctccagca cttcgtcctc ggtgtcgaag ggggcgatgt ggcagcacgg
     6601 cccgaagatc tcttccttga tcacgcgggc ggtttccggc aggccggtcc agatggtcgg
     6661 ctggacccag cagccatcgg caagctcgcc cgccatgtcg ggcacgccac cgccggtgac
     6721 cacggtcgcg ccctcttcca cggcgacctt gtagtaggac agcaccttct cctggtgctt
     6781 cttgctcacc agcgggccga agttggcggc aggatcatcc ggcacgccga tcttcatgcc
     6841 ttcggcgccg gccttgaggg cggcgacgaa cttgtcgaag atcggacgct cgacgtagac
     6901 gcgctcggtg cccaggcaga cctggccgca gttcaggaac acggagcgca gggtgccttc
     6961 gatggccttg tcgaagtcgc agtcggcgaa cacgatggag gcgttcttgc cgcccatctc
     7021 cagcgacacg gggcgcgagc cgttggccgc cgccttcatg atgacctcgc cggtgcgggt
     7081 ctcgccggtg aaggtgagcg cgtcgacgtc cgggtgggcg gtcaggaagg caccggcgga
     7141 gttggcgccg aagccgttga ccacgttgta gacacccttg gggatgccga ccttgttcat
     7201 cacctcgccg agcagcgcgg cggtgcgcgg ggtgtcttcc gagggcttga cgaccacggt
     7261 gttgccgcag gccagcgccg ggccgacctt ccaggtcatc agcagcaggg gcaggttcca
     7321 cgggcagatc acgccgacga cgccgaccgg gcgacgatag ccgtagttga tcgccttgcc
     7381 accgtcgggc gtgctcatct cgaagaactc ggtcgggacg ttcttgacca tgtccgcgaa
     7441 gaccttgaag ttggccgcac cgcgcgggat gtccacgtgc gaggccatgc tcttgggctt
     7501 gccggtgtcg gcgcactcgg cctcgaggaa gtcgtcgaag cggttgttga tctcgaccac
     7561 cagcgcctcg agcagctcga tgcgcttctg cagcgacatc gaaccccagg ggcccttcag
     7621 cgcggccttg gcggccttga cggcggcgtc gacttccttc tcgcccgcct cggcgaccat
     7681 gccgatcacc ttgttgttga tcggattgcg gttttcgtac cacttgtcgg tggcgacgta
     7741 ttcgccgtcg atgaagttga ggatcttgtc agtgatcatg atttctcccg ttgcgtttcg
     7801 gaacgtgtgt cgattgtagt gccgcttgtc gtcgtggcct cgtcgggcgg gcggcgtcgg
     7861 ggatggggtc ggggggcgtc cggacgcatg cccggcgcaa tgtgccgggc atgcgaagcg
     7921 gatcaggtca cgacggtcag gaagcgctcg ttgagcttgc ggtcgtggta gaagatgccg
     7981 gccccgacct cgtcgaaggt ccaggtgatc ggcgcgtggt cgggataggt ctcgtagccg
     8041 ccgcagaagg tctcgaagcg gttgcccgag gggtcgaagg cgtagatcgt cgaaccgcgg
     8101 gtgatgccgt ggcgggtcgg gccgatgtcg atcgacacgc ggttcatcga catgatgtcg
     8161 gcggcgcgca gcaccttttc ccagctgtcg agcaggaagg acaggtgatg cagcttgccc
     8221 ggctcggggt gggccacgaa ggcgaggtcg tgcgccttgt gcgagcacga gatgaaggtg
     8281 gcgagcaggg acttgccgtc ctccagcagc acgcgctcga cgaggtggaa gccgagcacc
     8341 tcggtgaaca gcttgaggtt ctcctcgagg ttcgggccgt agagcaggca gtggtcgaag
     8401 cggtgcgggg cgatgccatg ctcggaggcg gcgatccacg gatccgggtt ggtgtagggc
     8461 tgaccgttgc cgacgtcggt cttctcggca tacagctcca tgacgtggcc ggtggggatg
     8521 gtgaagcgca cgcgctcacc ggtctcgagc agttcgccgg ccgggatgcg ctcggtggcg
     8581 acgccatagg cctgcaggtc cttgtcgagc tgctctagcg tggccttgtc cttgaccttg
     8641 aagccgatca ggtccacgcc ggcacggtcg gcctggcgca ggatcacgct attgtggtcg
     8701 cgctcgtccc aggccttgaa atatacgcgg ccggctgcat cgcggccggt ctcgacgaga
     8761 ccgaccacgt ccttgtagaa cgccacgctt tcatccaggt ccagcacgcg cagctggata
     8821 tggccgggac gcatcactcc ggtagttgcc atcttgcatc tcctctcagg ggtcacggac
     8881 ggggttgcgg gcgccttgtg cgacccgcgc tccccgggtt ctcatgcggc gggtcgcgcc
     8941 cgcctgtttc tacgactgcc ttgcgtccgc ggccgccgct gacggcgtcg cgcacacgtt
     9001 cttcttcatc ttgccgagca ccgccaggcg gatgtccgac agcggcttaa cgcggcaggc
     9061 gaggacgatg ccggcggcct cctcctcggc gctgacgtag gcccggctca tcacgcgctt
     9121 gctgtactcg ccagcctcga cctgcacctt gcacacgccg cagccaccgc cgcggcagcc
     9181 caccgggatg ccgcgcttgc cgagccgctc catgcctgcg agcagggtct cgtcctcgcg
     9241 gcagcggtac acctcgccgg tctcgacgat ggtgacctga tggaacacct tgggcgcggg
     9301 ggtgttcatg tcaggccacc tgccgttcct gctgcgcctc gttgaacgcc ttcagccgcg
     9361 cggcctgcag ttcgcgcgcc gccgcgaggt tcttctcctt gacgtggccg aagccgcgga
     9421 tctcgtcggg cacgctcgcc agcgccaccg ccgcagcgtg gttcacaggg ttgagccggg
     9481 cgaggatctg gtcgagcagc tggatgtact cctcaatcag ctggcgctcg gtccgacgct
     9541 cctcggtctt ggcgaacaca tcgagcgaac tgccgcggaa gcgcttcagg ccggccaggc
     9601 gcttgaaggc cttgaacatc cactcgccgt actgcttctt ctgcggatga ccggtgaccg
     9661 ggtcggtctt ggccagcagc ggcggcgcga ggttgtactt gaccgagtag ccgtgcggga
     9721 actgcgcttc gagttcggcg aggaaggccg ggtcggtgtg caggcgcgcg acctcgaact
     9781 cgtccttgta ggccatcagc ttgtacaggt agcgggcggc cgcctcggca agcctggacg
     9841 aggacaccgc cttctgctcg cccgcgacca cgcgcttgac gacctcggcg tagcgcttgg
     9901 cgtaggcctc gtcctggaag gcgatgagct cggggacacg gatctcgacc aggcgcttga
     9961 cctcgccgtc ggcgccgatc gaatcgacga tcgcacgcgc ggccggcgtc agctgcggcg
    10021 ccatgttgag caccaccacc tggccgcccg acttctggcg cgccacctcg gcctcgacga
    10081 aggcacggtc gaccaccgcc atgcggcccc agcgaaaggc cgccaggctc atgtccaccg
    10141 ccacgccgga caggcggatg gcctcctcga tcgactccgc cttgagcggg atggtgccgg
    10201 cctggaaggc cacgccgacc atgaagttgt tggtcgccat ggcgtcgccg aacaggcccg
    10261 cggccagcgc ctcgccgtca aggaacacgt tgtgctcctt gcgggtgacg cggtcgatgc
    10321 cgccggtgag gccgctggtg gccgggaaca gcgccttgcg gttggtcacc atctggccgg
    10381 tcggggtctg ggtggtggac acgaccgcga tggtgcgctc cgggttgcac ttgtcgaggt
    10441 tcttcgggtc ggtggcgttg aggatgtcga agcccagata caggtcggca cggccgtccg
    10501 agatcttgtt cgaacccttg aacggggcgt gggtgatctt gatgtcggag atcaccgcgc
    10561 cacccttctg cgccaggccg gtctggtcga ggccgatcac gtgcttgcct tcgaggcgcg
    10621 cagcacgcgc cagcgtcgcc accacggtca ccgagccggt gccgccgatg cccatgacgt
    10681 ggatgccgaa gcccaggctg tcgtcgacct tgttgaccgg cgccggcagc tcgcgctcga
    10741 gcgccgggat gcggcccttt ttcttcttgg gcgcgccatc ggcggccggg gccggatgcg
    10801 gagtaatggt caggaaggac gggcagaagc ccttcacgca gctgaagtcc ttgttgcacg
    10861 aggactggtg gatgcgggtc ttgcggccga actcggtctg caccggctcg accgacatgc
    10921 agttcgactt ctcgccgcag tcgccgcagc cttcgcacac gcgctcgttg atgacggtga
    10981 cctcgaccgg ctcgtcggcc ttgccgcggc tgcgcgcacg gcgcagctcg gcggcacact
    11041 cctggtcatg cagcagcacg gtacagcccg gggtggcggc gagcaccttc tgggcctcgt
    11101 cgaggcggtc gcgatgccag acctcggtgc cgccgggcag ctgcacgccg ttgaagcgcg
    11161 aggggtcgtc ggtggtgacg atgatcttct tgacgccatt ggcgagcagg tcggagacca
    11221 tgttggtcac cgggacctcg ccctggatgg cctggccacc ggtcatcgag gtatgggcgt
    11281 tgcgcagcag cttgaaggtg atgttcaccc cggtcgaggc cgcgtagcgg atcgccaggc
    11341 tgcccgagtg ggcgtaggtg ccgtcgccca tgttctggaa gatgtgctgc gcctcggtga
    11401 agggcgccat gccgatccac tgcgtgcctt cggcgcccat gtgggtgccc atgaccacgt
    11461 tgcggcccat ccacatcgcc atggtgtggc agccgatgcc ggccgacacg atgctgccgt
    11521 cgggggcctg ggtcgaggag ttgtgcggac agcccgagca gaaccaggcc gtacgcaccg
    11581 ccgtcggcag cttgttgcgc gagtggatct cgtccaggcg cttgagccag ttctcggccg
    11641 attcgatgcg ggtcttgcgc gacaggcgct tcagcagcgc gcgcacgatg acgtcggact
    11701 cgaactcgcc gtagtgcggc agcagctcct tctcctcctc gtcgaacttg ccgacgatgc
    11761 gcggcgcgtt ggccatgccg tagagcacct gcttggcgaa catctccagg aaggggcgct
    11821 tctcctcgat gacgaagatc tcttccagac cctgcgcgaa ctcgcgcacg atggtcggct
    11881 ccatcgggaa cagcatgccc atcttgagga tgcggatgcc gtagcggcgc agcgcggcgt
    11941 cgtccaggcc catctcgagg aaggcctggt tgaggtcgtt gtacgtcttg cctgcggtga
    12001 tgatgccgat ccaggcgtcc gggttgggaa agacgacgtt gttgaggttg ttggcgcggg
    12061 cgtagcgctt ggccacctcg aggcggcggg tgtacagcga ctgctccatc tccagcgcct
    12121 cgacgcgcac gttcatgccc aggttcatgt tgggcgtgaa cagcttgccg tcgaactcga
    12181 ggtcgggggt gacgaagttc aggcgctccg gcgacacgct ggcggtgccg gtgccgtcgg
    12241 cgacgttggt gacgatcttc atgcccaccc acagcccgcc caggcgcgac atctggtagc
    12301 cgtgcaggcc gtagtcgagg atctcctgga cgttgcccgg gtacagcgag gggatgccga
    12361 catggaacag catcggctcg gactgcgagc acagcgagga gctcttgcag ctcgggtcgt
    12421 cgcccgcgat cgcgagcacg ccgccgttct tggcgatgcc ggtgtagttg gcgtgcttga
    12481 gcgcatcgcc cgagcggtcc acgcccggcg ccttgccgta ccacatgccg gtgacgccgt
    12541 cgaacttctg cttgccgacg gtgtgcagca tctgcgtacc ccacaccgcg gtggcggcga
    12601 ggtcctcgtt gatgccgtcc acgaagtgga tgtggttctg caccagcagc ttctgctgct
    12661 tgatcagcgc ggcgtcgagc atgccgacgg gcgaaccgcg gtagccggag acgaacatcc
    12721 cggtcttgag cccgcgacgg gcgtcggtgc gcacctggtc gagggtcagg cggacgatcg
    12781 cgtcgatgcc gccgaggtgg atgtctcctt cttcctgggt gaacgtgttg gagatttgct
    12841 tgccggatga catgagtgtc cttccccttt tatcagcccg tcgccgggcg ttttgtccgt
    12901 ctcgccccac ttgcgccgga cggcatgatg gaacgatctg gggcgcagat tagggggagc
    12961 ggccacacgg caatatccac ttcgtgcaca accgctatcc gctttgtgca gcagggaccg
    13021 gcctgcagag agtggatact gatgttgcaa gaactggata tttcacgcca atcgacctcc
    13081 ctacgatgcg aactccgcgc atcagacaac acaggagact ctggcgatga tcaccacgga
    13141 atatctggac tcactgattg aaaaggacaa ggaaaagggc ctgttccgct gcaagcgtga
    13201 gatgttcacg agcagtgagc tcttcgacct cgagatgaaa cacatcttcg agggcaactg
    13261 gatctatctc gcccacgaga gccagctgcc gaagatcaac gactactaca cgaccaagat
    13321 cggtcgccag ccggtgttca tcacccgcaa caaggacaac cagctcaact gtttcatcaa
    13381 cgcctgcgcc caccgtggcg ccacgctggc gcgcttcaag cacggcaaca aggccaccta
    13441 tacctgcccc ttccacggct ggaccttcaa caactcgggc aagctgctca agatcaagga
    13501 tcccaccgag accggctacc ccgagggctt caactgcgag ggctcgcacg acctcaagaa
    13561 gatcgcgcgc ttcgagtcct accgcggctt cctcttcggc agcctgaacc cggacgtgca
    13621 gtcgctcgag gactatctgg gcgaatcgaa gaagatcatc gacatgatcg tcgaccagtc
    13681 gcccgagggc ctggaagtgc tgcgcggctc ctcgacctac gtctatgaag gcaactggaa
    13741 gctgcaggcc gagaacggcg ccgacggcta ccacgtcacc gcagtccact ggaactacgc
    13801 cgccacccag gcgcagcgca agagccgcga cgccggcgac gacatcaagg ccatgagcgc
    13861 cggcggctgg gccaagaagg gcggcggctc gtactcgttc gagaacggcc acctgctgct
    13921 gtggacgcgc tgggacaacc ccgaagaccg tccgctgatg gaacagcgcg accgcctggt
    13981 gggcgagttc ggcgaagcca aggccgactg gatgatcggc aactcgcgca acctgtgcct
    14041 gtacccgaac gtgtacctga tggaccagtt cagctcgcag atccgcgtgt tccgcccgct
    14101 gtcggtcgac cgtaccgaag tcaccatcta ctgcatcgcg cccaagggcg agtcggccga
    14161 ggcgcgcgcc cgccgcatcc gccagtacga agacttcttc aacgcctcgg gcatggccac
    14221 gccggacgac ctcgaggaat tccgcgcctg ccaggaaggc ttcatggggc gtgcgctgga
    14281 atggaacgac atgtcgcgcg gcgccacgca ctgggtcgaa ggcccggacg acgaggccga
    14341 caagatcggc ctcaagccca tcctgtccgg cgtcaagacc gaggacgagg gcctgtacgt
    14401 cgcccagcac acctactggc tcgagcagat ccgcaaggcc gccgaagccg aagccaagaa
    14461 cgcataatcg gagacttacg agatgagcat ttcctacgag aacctgtgcg ccttcctgta
    14521 tcgtgaggcc cgtcacctcg acgaccgcga gtgggacgag tggctggcaa tgtacgacga
    14581 gaactgcacc ttctggatgc cggcatggga tgacgatggc gagctgaccg aagacccgca
    14641 gtccgagatc tcgctgatct ggtacggccg ccgttccggc ctggaagacc gcgtgttccg
    14701 catccgcacc gagcgctcga gcgcgaccat ccccgacacc cgcaccaacc accacatcag
    14761 caacatcgag gtggtcgagc agaacgacaa gacggtcaag ctgcgcttca actggcacac
    14821 catgagcgtg cgctacaacc acaccgacca cttctgcggc accagcttct acaccctgga
    14881 cgtgtccggt gcgagcccgc tgatcaagga aaagaaggtc gtcctgaaga ccgactacat
    14941 ccgccacgtc atcgacgttt accacgtctg acaacgaggg cggggcaccg cgcgccggca
    15001 acggcgcggg gcgaccccgc cccaaccggg agagacaacc atgacattca agatcgcgct
    15061 gaacttcgag gacggcgtca cccgcttcat cgagtgcaac gccaccgaga ccgtggccga
    15121 cgccgcctac cgccagggtg tgaacgtccc catcgactgc cgcgatggtg cctgcggcgc
    15181 ctgcaagtgc aaggccgaat cgggcaagta cgagctcggc ttctacatcg acgacgccat
    15241 gagcgaggaa gaggccaagc tcggctacgt cctcacctgc cagatgcacc ccaagagcga
    15301 ctgcgtggtg aacgtgcccg cctcgtccga ggtttgcaag atcaagcacg ccaccctcac
    15361 tgccaccgtc gccgaggtgc gccagctgtc gccgagcacg ctctccctgg tgctgcaggg
    15421 cgagggcgtc ggcaagctcg ccttcctgcc cggccagtac gccaacctca ccgtacccgg
    15481 caccgagcag acgcgcgcct actcgttcag ctccatgccc gcagacagca aggtgagctt
    15541 cctcatccgc aatgtgccca acggcctgat gagcggctac ctcaccggtg ccgccaagcc
    15601 cggcgacacc atcaagctcg ccggcccgat cggcagcttc tacctgcgcg acgtcgcccg
    15661 cccggtgctg atgctcgccg gcggcaccgg cctcgcgccc ttcctcgcca tgctcgacaa
    15721 gctcgtcgcg gctggcggca gcgcgcaccc gatccacctg atctacggcg tcaacaccga
    15781 cgccgacgtg gtcgagctcg agcgcctgga cgccttccag gccgcgctgc cgaacttcag
    15841 ctacgacgtc tgcgtggtcg ccgacgacag cagctggccg aagaagggct acgtcaccgc
    15901 ccacatcgag cccgcccacc tcaacgaagg caaggtggac atctacctgt gcggcccccc
    15961 gcccatggtc gaggcggtcg cccacgacct gcgcgagcgc aaggtcgagc ccaacagctt
    16021 ccactacgag aagttcgccg ccagcgtctg agcgctgccc atcctgtcag gagcgacaat
    16081 ggcaaaccgt ttcaagaaga aagtggccgt gatcaccggc gccgcgcagg gcatcggcaa
    16141 gcgcgtcgcc gagaagatgg ccaaggagaa gggcaccctg gtgctggtcg accgctccga
    16201 gctcgtccat gaggtggcca aggagctgtc cgcaaaggtc gaggtcctca gcctcaccgc
    16261 cgacctggag aagttcgccg actgcaagcg cgtcatggaa gccgcggtgg agaagttcgg
    16321 ccgcatcgac atcctgatca acaacgtcgg cggcacgatc tggaccaagc ccttcgagca
    16381 ctacggcgag gacgagatcg aggccgaggt gcggcgctcg ctcttcccca cgctgtggtg
    16441 ctgccgcgcc gccctgccct acatgcagga acagggcaag ggcgcgatcg tgaacgtgtc
    16501 ctcgatcgcc acccgcgggg tgaatcgcgt gccctacggc gcggccaagg gcggcgtgaa
    16561 cgcgctcacc gcctgcctgg cgctggagaa tggcgagcgc ggcatccgcg tcaatgccac
    16621 cgcgcccggc gccaccgagg cgccgccgcg cctgatcccg cgcaacacca aggagcagag
    16681 cgagcaggag aagctctggt acaagcagat ctacacccag tcgatcgaca gcagcctgat
    16741 gaagcgctac ggcacgctcg acgagcaggc cgatccgatc ctgttcctcg cctccgacga
    16801 ctccgcctac atcaccggca ccatcgtgcc ggtgggcggt ggcgacctgg gctgatttcc
    16861 cgcgtcctct ccctcccctc ggacgcctcg gccgcgctgc agcgatgcag cgcggctttt
    16921 tttcgttcgc acgatccgtg ccggcaatga atcaaaaaac tttatggata gaagcataga
    16981 cagggctttt ccatccaaat aaaatcgaga ttcttaagta tctcgaagaa cggcccatca
    17041 agaagccgac ttcgtcccac agagagcgag acagcctgca cgccaggcgg agaggagaag
    17101 cgcatgagca aggaacgccg gtttcagatg cacgtgagcc aactcgaatg gaggaccgcg
    17161 tgatgtccat ccgcttcctc aacggccaga gcaacgtctt cgccgccgcc aaccccttcg
    17221 aggtctccga atacgtgcgc gccaacgtgg gctcgcacag cctgcgcctg ccgcgcgcca
    17281 gcgacgccag cgcctcgctc agccaccgcc gcgccggcac cctcgacctg tgccgcctga
    17341 gctacggcgc gcaggcgcgc gtgctctccg agagcctcgg cgacatctac cacgcccagt
    17401 tcatcctgca gggctactgc agctacacgc tggccaaccg cacgctggac ctgcccgccg
    17461 gccacgtgct ggtgctcaac cccgacgagc cggtggacct cacctactcg gacaactgcg
    17521 agaagttcat cgtccgcatc ccctcgtcga tgctcgacga cgcgtgcgcc gagcaccgct
    17581 ggttcaagcc caacgagcgc atcaagttca gccccgagcc acagcgcttc gaggacatcg
    17641 acagcctgct gctgctgctg cgcctgctgt gcgaggaggc cgaatccgag ctggcgacgc
    17701 cgcagatgct gcagcactac tgccgcgtgg tcaccaccaa gctgatggtg atgctcaagc
    17761 acaacgtcag catggtcgcg ccctcccgcc acgcgcccag cttcgagcgc ctggtcaact
    17821 acatcgagcg caacatcaag ctcgagctcg gcgccgacga gctcgcccag tacgccgggc
    17881 tgagcctgcg ctcgctctac ctgctgttcg agaagaacgt gaagacgacg ccgaagaact
    17941 tcgtgcgcca gaagaagctc gagaaggtgc attcgatcct gaacgacccc gcccaggcct
    18001 gtccgaacgt caccgcggtg gcgctcgagt acggcttctc gcatctgggc cgcttctcgg
    18061 agctctacaa gtccacctac ggcgtactgc cctcgcagtc gatccgctgc cgccagcccc
    18121 aggccgggcg ctgagcgccg cgcggcgtcc accgccgggc gccgcacgcc cccatcccgc
    18181 cccgtacctg ccctgctccg ggcacgcgcg gtcacgacct caccaggaga aatccgccat
    18241 ggaacgcacc gcgatcaatc cccccgagct cttcagcggc aaggccttca gccagacctt
    18301 ctcgatcagc acgccgcagc ggctgatctt cgtgtccggc caggtcgact gcgaccgcga
    18361 gggcaaggtg cgcaaccccg acgacctcga ggcgcagctc aagggcacgc tcgacaacct
    18421 cgagatcgcg ctgcgcgcgc agggcgcgag catgcgcgac ctggtgcagg tgacgatcta
    18481 cgtcgtcggc ctgcgccccg aggacaccac ccgcatccgc gagatccgct ccgcctactt
    18541 cgacaccgag cgtccgccgg cggtcaccct gctcggcatc gagcgcctcg ccttccccgg
    18601 gctgcgggtc gagatcgaca tcatcgctgc gcagtgacgc agcagcccgg tacgccgctg
    18661 cgaggcggca tgccgggcac gactctccgt ctcgtgacgg cacggctggc gcgcgccgcg
    18721 tgccgccttc acgcgcgccc gctcagccct tgcgcggcgg attcaggaag ccgcgcagca
    18781 cgcgggtgag ccgcggcatg accacccagg tcatcgtcac cacgatcagc gcggtgagca
    18841 ccgcggtgcg cggcaggaag ggcagcggct ggatccaggg cagcacgaac cacaggaaga
    18901 aggacaccgt ggggaagatg cccagccagg tcaccagcgc catgcgcgcg cgcggcgggt
    18961 gcatcgtcgc cggcaccacc gcgggctcga accaggcctc gagcccgctc agcttgcgga
    19021 actccggctc gccttcggcg accgccttca tgcgctcgag cagcgcgccg cgggcgtcgc
    19081 tcatgtccca ggcctgcagc tcggcctccg aggcgaagcg gaccacgagc tgatactcct
    19141 cgcccggcgc ctcgggcggg atcaggtcgc cccccagaaa acccttgtgc tcgcgcatct
    19201 tggcgagcat ctcacgcaac atcccttcgt actcggcctc gtgcccggga cgggcacgac
    19261 ggcgggcgat gcgggtgacg cgggcgggag cggcggcagg tgcggcggcg ggggcattca
    19321 tcgaggactc tcctgttctg acggggcggt gaaaccgaac gggaagctca ccgcaggtag
    19381 agcgctactc taacgcataa ttctcgagat tttgataaat aatcgtgatt aacatttacc
    19441 atgatcacga tcgactatgc agggcacgca gcagacgaaa agaccccggc caccagggcg
    19501 gtgtgccggg gtcttgatca cgatcggagg cggcgaccta cagcggcatg atcagcttga
    19561 cgacgaactt gtcgccctcg aagcggttct ccaccttggt ctcgtggttc cactgcgcgg
    19621 tgaggtgcac gccgcccttg gtcgtgtagc tgaccgtggg gccgatggcg aagacctgcc
    19681 cgcgacggcc ttccgaccag aaggcgttcg ccgcaacctt ctgtccattg atctcgtcgt
    19741 cggtggtctg cttgagatag tagcccgaca ggcctacgcc ccagggcccg atgcgcttgc
    19801 cgacaagata gtccatgtgg aactcgtcgc ccgaagcgta gctgccaaca ccggccggac
    19861 cgtcgtagtc cttgttcttg gtcttgatgt tgtacatcag cttggccgag acctcccagc
    19921 cggtgtcgcc catataggtg aaggcgaaca gcggctcgta gctccagtag ttggccccga
    19981 tgctctggcg cgcatcgcct tccttgtagc gcccggtcgg cagattgatg tccaggccga
    20041 tcgcccagtg ccagttcttc gaatgccacg acacgatgaa cggatcgatc gtgatatcgc
    20101 ccacgccgtt gaccgacttg gagccgaaca gatcgacctt ctggtgcacc agtggcacga
    20161 tcacgtgcca accccagttg ccacccagga tcttgtgctc gctggtgtgc acgaagcgga
    20221 aggcgttgaa ccaggcgtcg acctcgcccg agggtgcctt gttgccgtcc ccgtcgcgca
    20281 gctctccgcc gtagtagccg aagtagttga tgaaatagtt gcccggcggc ggcaccgcgc
    20341 cgcccagcca ggtctcggcc ccgttggggt actggtcgcc gccatccttg gcgtgggcac
    20401 cgccgatcgc gagcgcgccg agcgcgaccg cagccgcaat cttgctgatc ttcatccctt
    20461 catctcctcc ttgattggtc ttgcgacgag tgtgctgctc ctggaccggc gccctctgcg
    20521 gggcgctcgg tgaatcctgc ctgcgactgc gcagccctca gcgtccgagg tcttttgccg
    20581 acaccccgcc gatgccccag ttggtcttgg gcacctcgcg gatgacgacg cggacggtct
    20641 ggatcggcgc gcccactgcc tcgacgagcg cctgggtgac tttctcgatc acggcgcgct
    20701 tctggtcttc ggtgcggcct tcgatcatgg tgatttctgc caacggcatg ctctgcccct
    20761 ccttgtcatc gaaacgatgg cgccctgccc ggtggcacga cgccgctgcg ttgcactcgg
    20821 ccccgatgtg gcgcgccccc gcggcatcgg ccagcggggg cgcagctcac attcaggcgg
    20881 ccagcccctt cgcccgggcg aggttcaagg ccgtatcctc gatcatgtct tcctgcccgc
    20941 cgaccatgcc gcgacggccc atctcgacga ggatctcgcg cgccggcacg ccgtacttct
    21001 tctcggcgcg cttggcgaac agcaggaagg agccatacac gccggcgtag cccagcgtca
    21061 gcgcgtcgcg gtcgatgcgg atcgggaagt ccatgatcgg cacgacgagg tcttcggcca
    21121 cgtcctggat cttgaacacg tccacgccgg tctcgatgcc catcaggtcg cacaccgcga
    21181 tgaagacctc cagcggggtg ttgccggcac cggcgcccag gccggcggcg gccgcgtcga
    21241 tgcgggtggc gcccacttcg agcgcggcga ggctgttggc cacgcccatc gccaggttgt
    21301 ggtggccgtg gaagccgagc tcggtctcgg gtttcagcgc atcgcgcacc gcggccagcc
    21361 gggccttgac ggtatcgggc agcaggtggc cggcggagtc ggtaacgtag atgcagttgg
    21421 cgccgtagcc ctccatcagc ttggcctgct tgaccagccc ttcggggctg ttcatgtgcg
    21481 ccatcatcag gaagccgacg gtgtccatgc cgagcttgcg tgccatgccg atgtgctgct
    21541 cggagacgtc ggcctcggtg cagtgggtgg cgacgcggat cgtcgatacg ccgagctcgt
    21601 gcgccatctt gaggtggtcg acggtgccga tgcccggcag cagcagcgcc gagaccttgg
    21661 cctgcttcat cagcgggatc accgcgccga ggtattcctc gtcgctgtgc gccgggaagc
    21721 cgtagttgac cgaggcgccg ccaaggccgt caccgtgggt gacctcgatc agcggcacgc
    21781 ccgcctcgtc gagcccggtg gcgatggtct tcatctgctc gagcgtcatc aggtggcgct
    21841 tggggtgcat gccgtcccgc agggtcatgt cgtggacggt gatcttcttg ccgcgaagtt
    21901 ccatgttcat ctccttttgg ccggggcgct caggccacca tggtggcgcg gttggattcg
    21961 agcttcagac gccctttgat gatctcctcg gcgaacatct cggcggtgcg cgcaccggcc
    22021 gcagtcatga tgtcgaggtt gccggcgtac ttgggcaggt agtcgcccag gccttccact
    22081 tcgaggaaga cggagacgcg gttgccgtcg aacaccgggc cgttgaccag gcggtagccg
    22141 ggcacgtact tctgcacttc ctggatcatg gcgtggatcg aggcggtgat cttctcgcgg
    22201 tcgggctcgg tctcggtcag gcaatgcacc gtgtcgcgca tgatcagcgg gggctcggcc
    22261 ggattgagga tgatgatcgc cttgcccttc ttcgcgccgc ccaccttctc gaccgcgccc
    22321 gcggtggtgc gggtgaattc gtcgatgttc ttgcgcgtgc cggggccggc gctcttggag
    22381 gacacggtgg cgacgatctc gccgtaggcc accggctgca cgcgcgacac cgccgcgacc
    22441 atcgggatcg tggcctggcc gccgcaggtg accatgttca cgttcatctc gcccttgccg
    22501 acatgctcgg caaggttcac cggcggcacg cagaacgggc cgatcgcggc cggggtgagg
    22561 tcgatcatca gcacgcccag ctcgttcaac ttgcggctgt tctcggcatg gacgtaggcc
    22621 gaggtagcgt cgaaggcgat ctgcacgccg tcggccttga cgtgcggcag cagcccgtcg
    22681 acaccgtcgg cggtggtctt gaggccgagc tcgcgggcgc gcacgaggcc ttccgagccg
    22741 gcgtcgatgc cgaccatcca caccggctcg agcaccgggc tgcgcttgag cttgtacagc
    22801 aggtcggtgc cgatgttgcc cggtccgatc agcgcacact tgatcttgtt catgcctgtc
    22861 ttcctttggg gttggatcgt ttccagggat gcaggccgcg cggcgatccg gggagaggga
    22921 gaggaacgga ccgccgcacg actgcaaccg ggagttgccc gcagcgcgga cgagaaaagc
    22981 agaatcagcc ggtcaggact cgacgtcgtc ggcgccgatc gcgagcaggc ctgcgcgcgc
    23041 gcagacgccg tcctgctcct cggacgcgcc cgagacaccg atgccgccca ccagttcgcc
    23101 accgacgcgg atcggcaggc cgccgccgaa caccaccagc cgcggctgcg ccgagaagcc
    23161 cagcttcatg ccctcgttgc ccgcgcacac gtccatccac ttcccggtcg ggaagccgaa
    23221 gccgccggcg gtgtaggcct tgtcgatggc gatcgcgatc gactgcggga aggcgccggg
    23281 catgcgcagg aaggcgacga ggttgccgga ggcgtcggca accgcgacgt tgatccgcac
    23341 cccgagcgcc tcggccttct cgaccgcggc ggcgacggcg gcatgcgccg cctcccagct
    23401 gatggtggcc tgaggaacag cgactttcat cgggtgagct cctgtggttc aggtttgatt
    23461 tgtaatgttt ttgaagatag gccaggccaa tgtcgacgtc aaggtttttt ctcgagattt
    23521 atagaagaag ctaattccat caccctggga tagaatcccg aatcggggtg tatccaacat
    23581 tgtcgcgatc atgaacgaag ccgtcccgcc aagaacaccg gaggccgtcg agcccaagac
    23641 cctcgtcgag ggcgcctacc agcgcctgcg ccgggacatc atcgagggcg tccacccgcc
    23701 cggcgagaag cttcgcgtcg aacatctcaa ggaccgctac gaagtcggcg ccggcaccct
    23761 gcgcgaggcc ctcctcctgc tcgtcaccga cgccctcgtg gtcgcccagg gccagcgcgg
    23821 cttccgcgtg tcgccgatct cgatcgagga cttcgaggac atcacgcgca cccgcctgct
    23881 gctcgagacc gaggccctgc ggcagtcact gcagctcggt ggcgaggact gggaagccgc
    23941 catcgtcgcc gccttccacc gcctgtcgcg cgccgaacag aagctcggcg acaacgactc
    24001 gctggccgcc gaggagtggg agcgccgcaa ccgcgccttc cacgaggcgc tgatcgccgc
    24061 ctcgccctcg cgctggatcc gtcacttcca gcacatcctc taccagcagt ccgaacgcta
    24121 ccggcgcctg agcctgttca gccatccgat tccgcgcgac atccacgccg agcaccaggc
    24181 cttgttcaac gcctgcctgg cccgcgacac cacgcgcgcg acctccatcc tcaccgagca
    24241 cgtgctgcgc acgctcgacg cggtcaagct gttgccggcg gagttcttcg ccggcaagcg
    24301 gaagtcctga gccggcaatt ccagaccctg cagcacccgc gtccgcaagt cccgatcttg
    24361 ccggcactgc gcgccgcagc gcacgcccgc cgacgaccct gccccctcgg cagggaccgc
    24421 cggcgcggcg gcgcggtcag gacaccacgc tcaggaagcg ctcgttgagc ttgcggtcgt
    24481 ggtagaagat gccggcgccc acctcgtccc aggtccaggt gatggtcttg tagtcggggt
    24541 aggtgtcgta gccgccgcag aaggtctcga agcggttacc cgaggggtcg aaggcataga
    24601 tcgtggtccc gcgggtgatg ccatggcggg tcgggccgat gtcgatcgag atgcggttca
    24661 tcgacatgat gtcggcggcg cgcagcacct tctcccagct gtcgagcttg aacgagatgt
    24721 ggtgcagctt gcccggctcg gggtggcgca cgaaggcgat gtcgtgcgcc ttggtcgagc
    24781 acgacagcca gatcgccagg tcggtcttgc cgtcttccat caccacgtgc tcgacgaggt
    24841 agaagcccag caccttctcg aagatctcct gcaccttctc gatatcgggg ccgtacagca
    24901 ggcagtggtc catgcgcgag ggcgcgatgc cgtgctcggc atcggggatc cacgggtccg
    24961 ggttcacgta ggactggccg ttgccgatgt cggtcttctc ggcgtagagc tcgatcaggt
    25021 ggcccgaggg aacctcgaag cgcacgcgct cgccggtctc cagcatctcg ccggcgggga
    25081 tgcgctcggt cttgacgccg aaggcctgca ggtccgcatc gagcttgtcg agcgtcgccc
    25141 tgtcggcgac cttgaaggcg aagaagtcca cgccggcgct ctcggcctcg cggatcagca
    25201 cgctattgtg ctcgcgctcg tcccaggcct tgaaatacac gcggccctgg ctgtcgcggc
    25261 cggtctcgac caggccgagg gtgttcttgt agaagttgat gccttcctcg agatcgagga
    25321 cacgcaggga gatgtgtccc ggacgaagta cgcctgtcat tgccattttg tctgctcctc
    25381 tcttgatgtg cccggaacgg aacccccgcc cgggtcggtt tgctcaatct tcatccgtcg
    25441 cgagacggat cctgccgtgg cccgcgccga cctgcaggcg cgcaccacga atcctcttcg
    25501 ctccgccttc agccttcgcc ctcttcgcag aggaagtcgc ccaccagccg cacgaagcgc
    25561 gcggagtgct cgatctgcgt ccagtggccg cagcggccga acacgtgcag ctgcgagcgc
    25621 tcgatccagc gtagtagggt ctccgaggtc tgcagcggaa tcacgcggtc gtcgcggccg
    25681 tggatgatca gggcctcgtg cggcagcgcg cggatgtcct gctcacggct ggcgagcgca
    25741 tccacccaac gctgtcgcgg tgcggggaac atgctcgcga aggactcctg gaaaccgggg
    25801 cggacgctgg cgcgatagcg cagctcggcc agctcgtcgt tcaccaggct gcggtcccac
    25861 gcgaagtagt ccatgatccg ccgcatgttc tcgaacgagg gcgtatagcc ccacaccgcg
    25921 tccagccccg cggtgatcgg aaagggcacc ccaacgctgc ccatcagcac cagccggcgc
    25981 acgcgctgcg ggtggcggat ggccagcgcc aacgcgagcg ccccgccgaa ggagttgccc
    26041 accacgtcgg cctgctcgat gccgagcgca tccatcagcc cgagcgcctg cgccacccag
    26101 gtgtccatgt cgtagcggat gtcggcgcgc cgctcggtga agccgaagcc cgccatgtcg
    26161 ggcgcaatca cccgcatgcg ctgcgacagc ggcgccagca ccagacgcca gttcgcccag
    26221 gcggagaccc cgggcccgga gccgtggatg aacagcgcgg ggaagccctc gcccaggtcg
    26281 tggtagttgg tcaggatgcc ggccgcgcgg atgctgcggc cgatctccgg atcgcctgcg
    26341 gcggacgcag gcgcgctcgg ttgcgctgtg gccgtggtgc ccattcgccc ttcctcgcgc
    26401 gcctcagatc ttcttgaaca gcgggctgcg cacctgctgc acgtccgcgg cggagaagaa
    26461 cttctccatg aagatgtcgc gctcgaacag ccgcccctgc atcagcgccg tgatgcaggc
    26521 gtcgatcatc agcggcgggc cgcacaggta ggccttgtgg ccgcggaagt cgttgtcgaa
    26581 gtgcgccgtc gccgcctcgt gcacgtagcc acggaagcca tcccagccgg aatccgcagg
    26641 ctcgtcggac aacgccggca cgtaggtgaa gttggggtgc ttcgcggcga gcgcgaggaa
    26701 ttcgtcgtga tagtagagct cggcgcggtt gcgctggccg tacaccaggg tcatgggccg
    26761 cgtgtcgccg gcctcgagca ggtcgaggat catcgagcgc gggctcgaca ggccggagcc
    26821 gccggccatg aacagcaacg cctcgggcgc cgacttgcgc acgaagaagc ggccgtaggg
    26881 ccccgacagg cgcacgcgct cgccgacccg cagctgctcg tggatccagg tggtgccgcg
    26941 gccgccgggc acgatgcgga tgttgagctc gacctcgcgg ccggtggacg gcgggttggc
    27001 gagcgagaag gcgcggctgt attccccgcc ctcgaggaag aagttgacgt actggccggc
    27061 ctggaaatgc atcggctcgt cggtctcgat gaagaccgcc ttgatcgtcg gcgtcagcgc
    27121 ctcgatccgc gtcaccgtgc cggggaagtc gcgcaccggg atggactccg cgtcgggatc
    27181 ctcctcgatc tcggcctcga tggtcacgtc ggactcgaga cgggcgcaac aggccagggt
    27241 cttgccctcg tcgcgctcga agtccatcag cgcgaagctg gaggcctcgc cgtgatcgat
    27301 ctcgccgtcg agcacctgca ccttgcaggt ggcgcacagg ccgtggcaac aggcgtgggg
    27361 cagccagatc cccgcgcgca gggcggcgtc gaggatggtc tggccctcct ccacctcgat
    27421 cgtctggccg atcggttcaa tcgtcagttc gtagctcatg gtgcgcttcc gttcttgtgc
    27481 gttctctggc ggggtgcgcg gggtgcggcg cgcgccgcac cccgttgcgg gcgatcagct
    27541 gcaggagccc ttgatgccgg cgaggccggg cgtgcggaag cggatcacgt ccttgtgctt
    27601 caagccgttc tcggccaacg acttgtcgaa gtcgagcgtg accggcttgc ccgacttgaa
    27661 ccactcggcc ttcgcccagt cgatctgcgc gaaatcgggg tggtagccga aggcggcctg
    27721 catcggcccg gcaacgacgt cgccgaagcg catggtcggc gggaagggga aggcaaaggg
    27781 cgcgcagaac agcaggtggt cttcccagcc gatgtacagc agctgggcgc cgtggaactt
    27841 gtcctgcgtg tcggtagggg cgaattcgta cttcgaaatt gcggcaacag ccatgtcttg
    27901 tctcctaacg atcgcttgag cgctgcgagc accggggcgc ccgcagcgtg cgtgggtcag
    27961 atgttcttcg tcgcctggcc gcgccactcg gcgaagttct tcttgtcctc ggaaatgtcg
    28021 aagtcgaggt tgtcgcggcc gtgctccagg ttgtagtact tcagcactgc ggcgagcggg
    28081 tcgaaccctt ccaccgtcgg gtcggtgccc tcggggaagc agttgccctg gtagatctgg
    28141 tgcaccggca gccaggcctg gacgtacttc tccggctcgt gctcgaagat ctccttgcag
    28201 tggtcggagc agaagtgata cttgtcgccc ttgtagtcga cctcgcggta gcagatcttg
    28261 gtcgcgtcgc ccggctcggt gaagatcatc gggatctggc aggtctggca cagcatgggc
    28321 agcgtcttgt tgtagaagcg gttgcccttg gcggcctgct cgcgccagaa ctcgtagcgc
    28381 gggcgataga gcttgtcgaa gctctccgga tacttgctcg acagccacgc catctcgtcc
    28441 tcgtcgggca tccaggtgtg gaaattggcg gcggcggcgt agttgtagaa ggtgctccag
    28501 gcctggtgcg acaggtggtc cttctcgagc gcgatctgct cggcgcactt gggcatggtg
    28561 atgccgtagc gcgcgaggtc cttgaacagc gcaccgccgt tttcctcgaa gtacacctcc
    28621 caggcttcct tccagctcat cgtgcgcttg ggcagcatgt agtccatcat catcgccacc
    28681 agggtcagca cgcgatagcc gcgccaggtc cacttgtcga tccagcgctg cacgatcggc
    28741 acgttggcgg gatcctgctc gaggatgaac ttgatcacct ccaggcccag cgtcatgtgg
    28801 cgcgcctcgt cggactgcgc cgagaagccg aaggtcatcg tgcccatgtc gccgttgtag
    28861 gccgcgccgg agacgaaggg cacgaacagc aggttggtca gcacgtactc gaacgagaag
    28921 ccgatcgaga ccatgaactc gaacgggccc gcggtgatgg cgtcgtcgaa gaaggacttc
    28981 ggcaccgaca ggaaccacac gcggtcgtgc atgtggtgga agtcatgcat gccgttgtag
    29041 tacttgttgt agttcgagat cgagtgcacc tgggtctgcg catgacggat ctcgtcgagc
    29101 gactgcatca ggcaggcgac gcgcgggccg gggccgggga aggcacgacc ggcgtgggcg
    29161 aagccgcggt gggcgacgta ctcgagcggg ctgatgccgc tgatgaagag cttgacggtg
    29221 ttgacgtagc gcgcgtcggt gacgttgagg tggccgttgt tctggttgaa ggcgtcgatg
    29281 atcgcgtaca gcttgcgctc cttctcggcc tggtacttcc agtaggcgtc catggtcagg
    29341 cggaaggggt cctcccactt gtcccagtcg tggatcttga tcccctcgta ggcgatgtag
    29401 gggtagatgt cttccatctt ctggtacgac ggggtccagt ccaggccccg ggtcatcacg
    29461 gcatagcgct ctttcaggcc gagcttcttc ttggcgactt gcatgtccat tttcgtgtct
    29521 cctcggggtc tcaggatttc cagaacaggg tgatctcgtc gtcggtctga tcgaggttgc
    29581 ccgacatggt gatcatattg acctgcagct cctgcaggtc gtagtcgcga ccgatgagtt
    29641 cctcgatggt ctcgcgacgc acgacgaggc gaccatcggc gttgatcttc accatcgccg
    29701 gctgctcatc cacaacggcg gaagggttgt cctgcaggat cgcctcgatg atcgggcgcg
    29761 tgtcttcgtt ggtctgcaat gcgagaaata cggtcgacat tgggtgctcc gctcagaggg
    29821 cgacgccggc cttggccatg cgtgcgttga attgctggac gacttcgccg acgacctcgt
    29881 ccgagcggtc gccgagggcg atgcgcgcga ccggcagcag ggctgcggcc gagcgatcgc
    29941 gccactggct gagccagcgc gccatcactt ccttgttctc gggcgactcg gccgcggcga
    30001 tcttcaccgt ggcgtcgacc cacttccggg tctcggtgaa ccagtcggtc atgaactggg
    30061 tgagcatcgc caccggcgtg ccgccctggg aagacagcac gtcgtcgatg atggtttcgt
    30121 acaccagggg gtagagcagg ccgtcgagcg cgacgttctg cgccacgaag agctccaccg
    30181 gatccttgat cacgaaggag tcctcgacat agcggcgcag gccctgccag gcgtcatcgt
    30241 ccatccaggc gcgcttggcc tcgtccagcg actcgacgtc gccgagcagc aggccgacgc
    30301 gggtgaggta ctgggcgatg ccgagctggt ccatcgcctg gtagatgtgc ggctgcgaga
    30361 agcccgtgcc gtagctgtag gcacagacgc tcgcgttgtt catgttcgag ccccaggcca
    30421 catggcgcag cggcagcagc agctcgagca cggtcttgcg caccgactcg ggcagggttg
    30481 ccgccaggcc acggttctcg acgaaatcga agttggcctc ggcggtgtcc tgctgcttgg
    30541 cgcgcgcaag ggtgtaggcg ccgtagtaga actggcgcgg atccttgaag gcgtaccagt
    30601 cggccatctt gatcgcagtg cgcgaggcat cgtagatgtc gtgcgcggga tcccaggtcg
    30661 ggcggtaatg gaagttcgcg gtctgctgca tgtccagcgt gccttcctgg tagcgcgacg
    30721 ccggcttgtc cgcgccgatg cggcgggcga tgttgtcgaa cgtctgccgc agcggcttga
    30781 tggtgacggt gcgcaaatcg atctgcatgg aatctcctcc tgtgtactcg tctgtcggcg
    30841 ctcagcggaa gcgctgatgg gtggcttgat gcagggtcca gttccagtcc ccggcctcgt
    30901 cctcgtcctt cgccgcctcc tcgcgcggat cgagaaagac gacgtggttc gactggcaaa
    30961 aggattcgta ggcgtccgac ggcaacaaca tctccgcgaa cagctcgggg tcgccgatgg
    31021 cgaactcgaa ctccacgaag ccgtccgggc ggcgctcgat caggcggacg aactttcgat
    31081 tcaggtccac cgccggttcg gtgttcttca tccccacact ccttcggatt gatcaacacg
    31141 ggctggccgc aggggagtac ctaacaagtt ccgtgccaat ctcaaaaaac ctttgcttat
    31201 ggcccgattc ggcatctttc tcgatatttc acccttgcag cgccgatttt cggcttcacc
    31261 aaatgatcaa acccggcgcc ccgttgatta tttgatttag tctatttatt gccctgcagc
    31321 aacccgcctt gccggcgaat cgccccaacc cgcttgacgg ccggcaccac ttcaggcgcg
    31381 cgcaggagaa ggacaggctc ggcgagatgg tgaaaagtcc ggttctttca cctaccccgt
    31441 atctttttct cgagattttc cacataatcg atggaatttc gcgccgcccg aagccaatcg
    31501 cctgaggtaa tctgaacact tcgcccggcc acgacgacga ccccggaaac caaccgccgc
    31561 agagcggaag cgaaacccgc ctggaggaga ccccttggcc agcatccaat acccggagaa
    31621 cgccgacctg cgcagcctgc tgcgctttgc cgcggaggac ggcctcatct ggctcggcga
    31681 gcaccgcatg ctgcttctgc acgccggcgc gatggccgag ctgcgcaagg agctgatcga
    31741 atcggtcggc cgcgagcagg cgcgccgcat cctcacccgc atgggcttcg cctcgggcat
    31801 gcgcgacgcc gagctggcgc gcaagacacg cagcggcagc gacctggccg acgccttcgt
    31861 gatggggccg cagctgcaca tgctcgaggg ctgtgcccgc gtcgagccgg tgcggctcga
    31921 gttcggcggc cccgacaacg gcttctacgc tgaattcctg tgggagaacg cctgggaggc
    31981 ggaagcgcac gtgcaggcct tcggcgagtc caccgagccg gtgtgctgga tgatgatcgg
    32041 ctacgcctcg ggctacacca gcgccttcac cggacgcttc atcctcttcc gcgagaccga
    32101 gtgcgcggcg accggacacg agcgctgccg catcgtcggc cgcccggcag aggactggcc
    32161 ggacgtggac agcctgctgc cctacttcca ggccgactcg atcgtcggcc gcctgctcga
    32221 gctgcgcgag gagatcgagg ccatgcgccg gacgatcgcc ggtccgcacc gcacccccga
    32281 cctcatcggc agctccaccg ccttcctgca cgcctacgat ctgatcggtc gcgcggcggc
    32341 gaccaatgtc tcggtgctgc tgctcggcga gaccggcgtc ggcaaggagc gcttcgcacg
    32401 cacgctgcat gagatgagcg cgcgcaagga cgaggccttc gtcgcggtga actgcgccgc
    32461 gctgcccgac gagctcatcg aatccgagct cttcggcgtc gaacgcggcg cgttcaccgg
    32521 tgcccacgcc tcgcgcgcgg ggaagttcga acgtgcacat ggcggcaccc tcttcctcga
    32581 cgaggtcggc gaactgccgc tgcccgcgca ggccaagctg ctgcgcgcgc tgcaggaagg
    32641 cgagatcgaa cgcctcggcg acgagcgcac ccgcaaggtg aacgtccgcc tcgtcgccgc
    32701 gaccaacgtc gacctgcaga aggcggtcaa tgccggcacg ttccggcgcg acctgtacta
    32761 ccgcctcaac gtctaccccg tgacgattcc gccgctgcgc gagcgcacgg gcgacatccc
    32821 cgcgctcgtc gaggccatgg tgcgccgctt cgagaccctg cacggcaagc acatcgccgg
    32881 cctgagcgac aaggcgatgc gtgcgctcaa gctgcacacc tggccgggaa acgtgcgcga
    32941 actcgagaac gtgctcgagc gtggggtgat cctggcgccg ccgaacggcc agatcgaggt
    33001 cgaacacctc ttcatcgcca cgttcgacga acacgcccgc gagcactcgc tcagcgccca
    33061 gggcggtctc gaggcggcac agcgggagca gcaggatctc gccacggcgg tgctcgactc
    33121 ggggatctcg ctcgacgcct tcgagcagcg cctgctgcaa cacgcggtcg agcgcgccaa
    33181 cggcaacctc tcggcagcgg cacggctgct cggcatgacg cggccgcagc tgaactaccg
    33241 catcaagaag cagggcgcgg gcgggtgagg cgcgaggagg tggcgcttgt gcgccccttc
    33301 ctcacggacc gacgcgggat ggccagttct gggcgcagac agaaaaaagc caccgtacgg
    33361 agaccatacg gtggcttttt tggtggcgga gtggacggga ctcgaacccg cgacccccgg
    33421 cgtgacaggc cggtattc
//
LOCUS       DAOTIN010000028        33386 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_1457_length_33386_cov_9.093637, whole genome shotgun sequence.
ACCESSION   DAOTIN010000028 DAOTIN010000000
VERSION     DAOTIN010000028.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 33386)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 33386)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33386
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1457_length_33386_cov_9.093637"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..146)
                     /locus_tag="P5537_06370"
     CDS             complement(<1..146)
                     /locus_tag="P5537_06370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF485 domain-containing protein"
                     /protein_id="HRV77705.1"
                     /translation="MENDMAAKIAANPKYQKLVGTRSSFGWILTMIMMVVYYGYIAII
                     AFNK"
     gene            complement(381..1643)
                     /locus_tag="P5537_06375"
     CDS             complement(381..1643)
                     /locus_tag="P5537_06375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HRV77706.1"
                     /translation="MPPSLVPPPLQLPLGLRDVAALGQVFTPEPVVRAMVALRRNPGR
                     VLEPSCGDGAFLRHLPGAVGIELDPDHCPPGAQAIDFFAYPERERFDTIIGNPPYVRI
                     QDIAEGTRALIERGAYGELLDGRANLYLFFIAKCLRHLRPGGELIFITPRDFLKATSA
                     VKLNRLLVESGSITDAIELGDARVFDDAVPNCLIWRFEKGRSARAMRYCALGVGDDLA
                     AGLTAPAWEERHFVEAGGHLMFARGDYPLRLADVAFVKVGAVSGADELFADAVHGNRD
                     FVCSSTVGSGLTRRMIWSEPGDPPPAVLAPHKARLLQRKVTRFDESNWWMWGRLHHRS
                     AQPRVYVNGKTRVAKPFFIHPCTDYDGAVLAVFPRRADVDIEAFRDALNAVDWEDLGF
                     VCDGRFLFTQRSLEHAPLPAVFAAFVPA"
     gene            1736..2713
                     /gene="cysK"
                     /locus_tag="P5537_06380"
     CDS             1736..2713
                     /gene="cysK"
                     /locus_tag="P5537_06380"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HRV77707.1"
                     /translation="MSTWYPDNAESIGRTPLVRLNRVLDGAQATVLAKIEGRNPAYSV
                     KCRIGAAMVKDAIAHGRLGPGQEIVEPTSGNTGIALAFVCAARGIPLTLTMPETMSVE
                     RRKLLVAYGARLVLTEGPKGMNGAIAKAREIVDSDPGRYVLLQQFENPANPAIHETTT
                     GPEIWNDTDGGIDILVSGVGTGGTITGISRYIKRVRGKDIQSIAVEPTASPVISQTLA
                     GQPLTPAPHKIQGLGAGFVPKVLDLSLIDAVEQVTNEDAVLYARRLAREEGILAGISC
                     GAAVAAAARIAKQPENAGKTIVVILPDSGERYLSSILFEGLFDEKGIAI"
     gene            2721..3086
                     /locus_tag="P5537_06385"
     CDS             2721..3086
                     /locus_tag="P5537_06385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HRV77708.1"
                     /translation="MTIRVRRAYDPPAAGDGCRVLVDRLWPRGLARENARIEHWLREL
                     APSHELRRWFAHEPARWDEFRLRYADELRAPATAAALAELRGLLAAHPVLTLLHGARD
                     TTHNNAEALRQWLARGGPS"
     gene            3266..4312
                     /locus_tag="P5537_06390"
     CDS             3266..4312
                     /locus_tag="P5537_06390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HRV77709.1"
                     /translation="MFRLPWSTTKNASAPLALALQGGGAHGAYTWGVLDRLLEAGVPI
                     EGISGTSAGAMNAVALAEGWTTGGADGARAALDRFWTAVGDSVPFHLELLHNLNPSGD
                     GSLPSPMNVMLGLARVFSPYQLNPFDLNPLRDVVRAQFDFERIRRACPLKLFIAATAV
                     RTGKVRLFRTAELGEAAVLASACLPTLHHAVEIDGEHYWDGGFTANPAIYPLLYECDT
                     PDLLMVLLNPLQHEHAPRSAAEIATRSMELGFSTTFLREMRMIAHARQFIAERPRWSP
                     IGRLERRLLHERFHLIDAPELGDAGSASKLDATASSLLRLRELGRARAEAWLQIHANG
                     VGRRETIDVGTLFL"
     gene            complement(4337..6328)
                     /locus_tag="P5537_06395"
     CDS             complement(4337..6328)
                     /locus_tag="P5537_06395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl CoA:acetate/3-ketoacid CoA transferase"
                     /protein_id="HRV77710.1"
                     /translation="MARKTHPMVASLRAADTGKIVSAREAVRLIRSGDTVATGGFVGI
                     GFAESVAIALEQRFLEAEGALAGPRDLTLVYAAGQGDGKTRGLNHLGHEGLVARVIGG
                     HWGLVPRLQALAVDNRIEAWNLPQGVISHLFRDIAAGKPGTLTRVGLGTFVDPRFGGG
                     KLNARTAEDLVRLMPIDGEDYLFYKAFPIHVGIIRGTTADPDGNVTMEKEALTLEARA
                     IAMAARNSGGIVIVQVERIAERGSLNPRQVQVPGVLVDCVVVADRPEHHMQTYAEQYS
                     PAFSGEIRVPMSTICAMPMGERKIIARRAAMELQSDAVVNLGIGMPEGIAAVAAEEKV
                     IDLLTLTAEPGVVGGIPAGGLSFGAAVNTQAIIDQPSQFDFYDGGGLDVAFLGLAQAD
                     REGNLNVSKFGPRLAGAGGFINISQNARKVVFVGTFSAGGLEVAVEHGRLRIVREGAA
                     RKFVDAVEHRTFSGAQAVKWKKDVLYVTERCVFRLCEEGLELIEIAPGVDLQRDILDR
                     MDFVPVMKAPPVLMDARIFVDAPMGLRHDLLDVPLERRLAYDAQQDVFFVDFEGLSVR
                     TPQDIAAIRDAVSAALAPLGRKVDAVVNYDRFSIVPELVDDYVGMVKGLMDTHYHTVT
                     RYTANGFLRMKLGVELEKRRIPAHFYASASEAWNGLETP"
     gene            complement(6474..7079)
                     /locus_tag="P5537_06400"
     CDS             complement(6474..7079)
                     /locus_tag="P5537_06400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004391474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HRV77711.1"
                     /translation="MPWPADFELACRWYEAQMPRLYDDFQVRALDIQQLARIAATSPS
                     RQRFLTELTLDPPSATSGEAGMPLLDEDYLILSTIHSAKGQEWSAVSVLNVVDGCIPS
                     DVATRNSAEIEEERRLLYVAMTRAKDALDLIVPQRFHVTQQMGLGDRHVYAGRSRFIP
                     NRLLGRFEQASWPPPAPELQGSPASRQAAIDLAAKMRDMWR"
     assembly_gap    7348..7447
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<7448..9059)
                     /locus_tag="P5537_06405"
     CDS             complement(<7448..9059)
                     /locus_tag="P5537_06405"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HRV77712.1"
                     /translation="MVTPIETLPGPHSEPHSASRAGADAPQLAAANPLAALDPAQRAA
                     VEHGIGAEGRIDAGPLLVIAGAGSGKTGTLAHRVARLVAAGADPGRILLLTFSRRAAD
                     EMGRRVRRILAQAAADRPGLARAELPWAGTFHAIGARLLRDYAGRIGLDPGFSIHDRE
                     DSADLMNLVRHELGLSATKQRFPQKGTCLAIYSAVVNTRAALAEVLQASFPWCAQWED
                     ALKRLFRAYVDAKQAQQVLDYDDLLLYWAQMVSDPGLGAEIGGLFDHVLVDEYQDTNA
                     LQATILLAMKPDGRGLTVVGDDAQSIYAFRGATVRNILDFPAAFAPPARVVTLERNYR
                     STQPILDAANAVIALAAERFAKNLWSERASAQRPRLVTVKDEAAQADFVVDSVLARRE
                     EGLKLKQQAVLFRASAHSARLELELTRRNIPFVKYGGLRFLEAAHVKDVLALLRWAEN
                     PRDRIAGFRAIQLLAGIGPKTAGRVLDNVCAAPPGCALLAEQPVPEAARAGWLEFATL
                     LDRLAGREEAPSAAFAPAGAPTETAVLPE"
     gene            9158..9802
                     /locus_tag="P5537_06410"
     CDS             9158..9802
                     /locus_tag="P5537_06410"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77713.1"
                     /translation="MPAPDPVLPSCLQPRRVILFSGHMIDAPGRTEPRFPPALAPAAA
                     ARIAAALDDLGAGPLDLGLTQGAAGGDLLFAEAAQARALPLLFLQPFGEDEFLARSVR
                     PVSEGEQWVARYRAVAARLASPPRAMPPAAAAEEADNPFERCNRWLLDTALACGGDRV
                     WLLCLWDGHRGDGAGGTAHMVEEVSRHRGHVLHIDTHDLQAHDPAGSRPDAGLA"
     gene            9856..15378
                     /locus_tag="P5537_06415"
     CDS             9856..15378
                     /locus_tag="P5537_06415"
                     /inference="COORDINATES: protein motif:HMM:NF024180.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAT domain-containing protein"
                     /protein_id="HRV77714.1"
                     /translation="MSIPRFRLRGSIAPTPPASSASTAATPDDGLVAIASRRTLIPGR
                     ARDGVSGELEVAGDEVVRVELDNGFVLWTRADALVREHGRRSRARDGGDAWEIDALAP
                     SANAATAERGLLGLGVRVLEFFGVRVKEGAARKLGEHFEERQLKPQPPGLHRVSLADR
                     FALAPLAADAKLPGGGPLLVFLHGTASSCEGSFGKLWDAGNAAGAAARTRLAAAYGER
                     VFALEHRSLTESPVTNALALARRLPQDAELHLVSHSRGGLIGELLCLGQCEGVRRLLD
                     AEGLHTLFAADRTIAEQLGLQPLSPKEAKARDHAYDADRAALAELVELLVERKVRVTR
                     FVRAACPARGTTLASGRLDRWLSMLDFLAGRALGGGLFADGLDFLLAVVKERTDPRTL
                     PGLEAMMPGSALTRLLHHPDLVTAADLSVIAGDAEGDTVWQKLKLLVTDWFYGADHDL
                     VVNTGSMSGGLRRPDGGARFRLDRGARVDHFSYFRNADSVGWLLAGLTRGDHEDGGFR
                     PLAEAPQTPPRWREAVRRARGGGPRPLTVMLPGTMGSALSAGGRAVWLHYFTLLRGGL
                     GKIELGAREVSADDLLDDFYGPLLEFLAEHHRVEIFPYDWRLSVRAAAARLAAALEGW
                     LPQAEREGQPVYLVAHSMGGLVARAMIADGGRGAAVWQRITRLPGSRLLMLGTPNLGS
                     YEAVRWLTGFNPTQARLALLDFTRSTAEVVDLVREYPGLVELLPFAPEDPDFADPARW
                     TLLRESLQAQWKTPPAEALRSARETWTLLRAAPPEPAYMAYVAGCQRATVIDYELQDH
                     DEDSWLSGRKRIAFIAGREGDGTVSWASGLLPGVPTWYVDDTAHDALCVQRKAFAGYL
                     DILAKGATTRLPSAPPQRARALADEPTRFELPPLPPADGIPAPSELRSLGFGGGVPAS
                     PPEARATTPPIELSVRHGDLSYARFPVLVGHYRGDTIVSAEAALDRRLDGALSRRQAL
                     GLYPGQHGSSAQFFNPRPEARPAGAIVVGLGEVGELTPGLLEAGVRGALLDHALQIAQ
                     WPDERFGPAGGPRRASVSCLLVGTGAGALSVRDSVEAIVRAAIAANARLHETELDGRV
                     WIDRIEFVELFADVAIGAAESLQAVLAIPQLGAAARWPAQAIEAGRGGRVRVRFDEAP
                     EWWQRLEIIEDEGRRDSLRFIFVTDRARAEETLASGQLALADAFIREAAASPAANPEA
                     AFTLHEMLLPVSLREAASRQGNLVLLVDPRSARYPWELLENRWSDSGRPPAVAAGVVR
                     QIRTTQYRTRPVHADEASILVVGNPDLDGWEDFPDLPGARAEASEVAECFETAGWRVE
                     RCIDPPTHEVLAGLHRNPWRILHLAGHGEHDFPLPQARRKPGDPPAAEPQTVSGMVIG
                     RDTFLTPGDVEQMRWVPELVFINCCHLGSMRGSDKGALAANLGMQFIKMGVRAVVAAG
                     WAVDDAAALAFANTFYRLMLAGETFGEAVRAAREEVWLRYRGVNTWGAYQCYGDPSYT
                     LLRGRPAPRPQARRFHCPTELGVELDNLTQALRSSAGDDAAARIAALLEGIPESAREA
                     WLARADLCAALGFAWAEARAWPEAIEQLDRAIRAAAGDCPLRVLEQLANCRARLAADE
                     ALAAHRRGAAADTAQAKAREELVQAALAELEPLCRRAPTVERLSLLGSTHKRHALVAA
                     APAARLEALDACAEAYREAFEAGGSQDAYPFTNWASAVLLAAHLDTAHPGLPPAALEE
                     ELPRLRTSLQEGAGRSPDFWTAASLADLDLVQLLACSLHPAEPAARGRKRAAATTEAC
                     AALAGQILATYRDALARGASPRERASLVENLDALLVLLEGGPPVLGERLRQIRDAI"
     gene            complement(15413..16060)
                     /locus_tag="P5537_06420"
     CDS             complement(15413..16060)
                     /locus_tag="P5537_06420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004375940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HRV77715.1"
                     /translation="MQTEKPLILFVHGLWMHGVVFSAHRRQLRRMGRESRVFSWHSLL
                     GSLDGATDELAAYIAALGRRPLHLVGHSLGGCVVLNMLARHHPEGIGRVVLLGPPCCG
                     SYAGERILRVPVLRGALGRVLPQWLARPLPEVPPGYEIGVVAGNRPVGMGRIVPGMEK
                     PNDGMVTVAETRWPGARDHAVLPVTHMQMLWSRACLIQTLHFLDTGRFLRGGVRA"
     gene            complement(16071..>16514)
                     /locus_tag="P5537_06425"
     CDS             complement(16071..>16514)
                     /locus_tag="P5537_06425"
                     /EC_number="3.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004318979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016799 - hydrolase activity, hydrolyzing
                     N-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0009691 - cytokinin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LOG family protein"
                     /protein_id="HRV77716.1"
                     /translation="GNRGAFDAGGRSMGMSIFLPFEEAPNPYITPELCFQFHYFAIRK
                     MHFLMRAVALVSFPGGLGTLDELFEVLTLTQTRKIRRRPIVLVGRDFWQRLIDFDVLV
                     EHGVISPEDKNLFHYAETAEEAWDAIKAAYSGDNPALTARQLKGN"
     assembly_gap    16515..16614
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<16615..16793)
                     /locus_tag="P5537_06430"
     CDS             complement(<16615..16793)
                     /locus_tag="P5537_06430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004318979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HRV77717.1"
                     /translation="MSKNTPLRARNFPSAEDEAKAAQPHGRYDGPGSSFRMAFTDTDF
                     LLREELRPVRLQLELL"
     gene            complement(16877..17779)
                     /locus_tag="P5537_06435"
     CDS             complement(16877..17779)
                     /locus_tag="P5537_06435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014238115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HRV77718.1"
                     /translation="MTIELRQLRYFVALADTLHFGRAATQLHITQPPLSRQIAALEDT
                     LGAALFVRSSRQVELTAAGRHFHEHAVRVLAALDGAVRSTQATARGERGVLRVGFTMS
                     AAWNVLPALIRRYGDAFPAAEIQLSEVVPRELDEALLSGRADVGIAFPWQRPDGLEYL
                     RVHAEPLWAVLPAGHPLAAAAVVAVGELADEPFITFPAATAPALHALVAGCCREHGFE
                     PRIRLETHLQQTIVNLVAEGLGVSLVPRSMSRMQLAGAVFRPISSPRVIEQGVIWAPN
                     NANPCLARFLDCARAFGEAMAGGD"
     gene            17875..18816
                     /locus_tag="P5537_06440"
     CDS             17875..18816
                     /locus_tag="P5537_06440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014238114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HRV77719.1"
                     /translation="MSAIVNVVLPIFGLILAGYVCRRSGRLGETASNELSRFVVWLAL
                     PALLFNVTATASWEQLWQPGFIASVCAGCALVFAATVALRVRKSGRLVDASIDGLSAA
                     YANTGFLGIPLCALVFGDAGLMPAIVATLIVACLLFAVGIVLVEIGLQKEKHPLRALL
                     KVARALAANPLLVAPVLGCTWAAFGAELPAPAARFLSLLGAAATPCALVSIGLFLAQK
                     HEGQHDGATGLVLAKLLLQPAITAFLAFRVFELPALWASAALLLSALPTGTGPFMLAS
                     YYGRDAALVARVILLTTVGSVVTVSICLNLLANLAPV"
     gene            complement(18836..20038)
                     /gene="modC"
                     /locus_tag="P5537_06445"
     CDS             complement(18836..20038)
                     /gene="modC"
                     /locus_tag="P5537_06445"
                     /EC_number="7.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004375946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015412 - ABC-type molybdate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein"
                     /protein_id="HRV77720.1"
                     /translation="MAEHPLATGASTAIAAHAVATAATASAATGASGAAQGPTPSAAG
                     IEARFAVDYAGFRLDVDLRLPGRGVTALFGHSGSGKTTLLRCVAGLEPAARGRLVVNG
                     ECWQDDARGIQVPTHRRELGYVFQEASLFPHLSVRRNLEFGLRRIPTAARRVRLEHAV
                     ALLGIEALLERMPDRLSGGERQRVGMARALLTSPRILLMDEPLAALDHRRKQEILPYL
                     ERLHDELDIPVLYVSHSPDEVVRLADHVVMLGAGKVMAAGELHATMARLDLPTAFTED
                     AGVVVDGTVAEHDDHDHLTRLDFPGGAVWVQRQPVALGRRLRFRIHARDVSLADHKVE
                     GTSIVNLIAVTVKEVVGADSPAHVLVGLDAGGTALIARITRRSSAQLGLRPGLRMWAQ
                     IKSVALLG"
     gene            complement(20038..20724)
                     /gene="modB"
                     /locus_tag="P5537_06450"
     CDS             complement(20038..20724)
                     /gene="modB"
                     /locus_tag="P5537_06450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004375947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015412 - ABC-type molybdate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HRV77721.1"
                     /translation="MPTLTGADWSAIRLTLELAAVSTVVLLLLGTPLAWWLACTRSRW
                     KGVVGAVVALPLVLPPTVIGFYLLVAMGPNGPLGRLTEALGLGLLPFSFAGLVVGSVV
                     YSLPFVVQPLANAFEAIGRRPLEVAATLRAGPWDRFFNVALPLARPGFVTATILGFAH
                     TVGEFGVVLMIGGNIPDRTRVVSVAIYDHVEALEYAQAHWLSAGMLAFSFVVLLALYG
                     RRGNAGGGVG"
     gene            complement(21195..21995)
                     /gene="modA"
                     /locus_tag="P5537_06455"
     CDS             complement(21195..21995)
                     /gene="modA"
                     /locus_tag="P5537_06455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004318987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009897 - external side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015412 - ABC-type molybdate transporter
                     activity [Evidence IEA];
                     GO_function: GO:0030973 - molybdate ion binding [Evidence
                     IEA];
                     GO_process: GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HRV77722.1"
                     /translation="MGSSRLPPRRRVLGVLLALAAGVCAPTATAGERVTVAAASDLKF
                     ALDEIVAEFGRAHPGDVVEVVYGSSGKFATQIRQGAPFDLYFSADIAYPRTLEAEGLA
                     HGTTRPYALGRIVLWSATRDARSLELKDLADPVLGRIAIANPRHAPYGKRAEEALRAA
                     GVWEAVQPRLVQGENIAQTAQFVQTGNAAVGIIALSLALNPTLAAQGGYHLIDASLHA
                     PLEQGFMLTRAAAGKPLAGAFAEFIGSESARTVLRRYGFELPPAPAGR"
     gene            complement(22246..23265)
                     /locus_tag="P5537_06460"
     CDS             complement(22246..23265)
                     /locus_tag="P5537_06460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHB depolymerase family esterase"
                     /protein_id="HRV77723.1"
                     /translation="MSRRVRPSPLLRAIERATTAMTRRAIRAGANAAGKAAARGVEAM
                     SAPYRLPASTGDWVTGQAIGPGGLRRFRLFRPAGVRSSERLPLLVMLHGCGQNAAAFA
                     RSTRMDRLASRERFLVLYPEQDLAANPQGCWNWYDTRSHRAEAEAATLIAAIDQACLL
                     YPVDRGAVAVAGLSAGASMAALLAVRWPERFCAVAMHAGVAPGAARSAAGALAAMRGR
                     SLPETAVERGNRPPLLVIHGSDDRVVSVRNAHAAAEQWAAALGARAAVPRRVQRGARH
                     PMTVSDWRAQRRVCVRLCEVERLGHAWSGGVADEHFSDPRGPDASTLIWRFVQASLGG
                     VGNEA"
     gene            23486..24403
                     /locus_tag="P5537_06465"
     CDS             23486..24403
                     /locus_tag="P5537_06465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004385027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-type lectin-domain containing protein"
                     /protein_id="HRV77724.1"
                     /translation="MRTPCPDQAGRRLRHARTLLCAATLCALATAPAHATLINYQNFD
                     NLSAFTLNGATAGINTGGQGVVGPSGARVLRLTNALSQAGSAFLTSPFSLAADASFSS
                     YFEFQFTNQINNGADGIVFTVQTVANTAGGSGGGIGYQGLSPSVGVEFDNWNNGGGDG
                     NNDNHAGINVNGNMASVVRADTLPAQLDSGSVFHSWVDYNGASDKLEVRLALTDTRPA
                     AALMSYTVDLVTLLGTTNAFIGFTSGTGAAGAYHDIRRWVFTGEFNPIVDPDDPVDPG
                     TVPEPGSLALLSLGLLGAFAGLRRRALAT"
     gene            complement(24452..24688)
                     /locus_tag="P5537_06470"
     CDS             complement(24452..24688)
                     /locus_tag="P5537_06470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004385025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77725.1"
                     /translation="MAQPTLKQRKTFALIRIFGGMVAALYLSFVVVTNMLAGHALEGE
                     LLYSALVALAGYGYAAWYLRELAAVAREERGGGG"
     gene            24893..26314
                     /locus_tag="P5537_06475"
     CDS             24893..26314
                     /locus_tag="P5537_06475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused MFS/spermidine synthase"
                     /protein_id="HRV77726.1"
                     /translation="MHAPAPGRPGTAPAAASPAPALSPALLFLLVFVEGFVSLGAEIL
                     ALRRLVPHVGSAITVTAPTIAFFLLALALGYQAGGRVADDYLARVRRNFLLAAALIAL
                     GLAGPVVELAFAHLQPAPVAWAVVVCGVLCPVAWLLGQTVPILTNLLRHERIGARSGA
                     ALYWSTLGSFLGALTLSMGVMQWLGVGAAVLVCTGLLLAAVPALGRVAGARMPSAVAA
                     LVIALAALAVNLVLPQQLETAYATYRVEAVEIPGYVAPEVFRINNSPASILDAGEQPR
                     YARYIRRLRGLLLDELGFRGRSVLVLGAGGFTLSHREPLNHYVYVDIDPAVKEIAERD
                     FLREPVRGEFVAADARAHLRATAARHDAVVVDVYSALTSIPAHLVTREFWRATRAALK
                     PGGVLAANLILDRELASPYARSLLASIQAEYGACAVEVLFRDRPQGNVLVICTAPSAA
                     PAEPAHPYTDERNRADLDVLRGG"
     gene            complement(26315..28741)
                     /locus_tag="P5537_06480"
     CDS             complement(26315..28741)
                     /locus_tag="P5537_06480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HRV77727.1"
                     /translation="MKDDNARLRAAIDKLRVPIYIKDPQGRYGYANDLACELLECSRT
                     DVLGRSDSELFPPDLADAMQAHDRRAMAGREPVIAEERLRLPGHPEMTWGLSIKQPLF
                     EEDGRPDGVAGLTIDITARKRAERELVALKNDYAAILQALPDPLFVLDAEGRCLSYRT
                     PSEALLAAPPSLFMGRTVREVLPPAEAETCLEALREAAARGHSSGKVFKVDTPGGMRW
                     FELSVAPMARSGDEPQRFNVLSREITVRKKMEQALQERESLLRAVVDNTPVEYWARDL
                     QGRCIMQNAMTAAHWGDLLGKRVEDSGETEPVSADWGESNRRAYAGETVHKEVEYEID
                     GERRTYQCLVAPIRVDGEVVGIFGFNQDVTERKRQERQIHELAFFDPLTGLPNRRLMY
                     DRLDHALRASARRGTEGVLLLIDLDHFKDLNDSHGHDAGDQLLVEAGVRLNACIRQGD
                     TAARLGGDEFVVILEDLDGIAQASAIASRICEELARPFHLRCGKDDERITHQVSASIG
                     VGAFGRAELGAAELLRRADTAMYQAKAAGRNAICFFDPAMQAAVTERAILHADLREAI
                     RRGQFELHYQVQVDSRRRPSGAEALLRWRHPHKGLLAPGGFIELAEETGLIVPIGHWV
                     LETACRQLARWSLQTQTAHLQLAVNVSARQFRQPRFADEVRALLAQTGAPAEQLKLEL
                     TESSLIEDAEGVIERMEALRALGIRFSLDDFGTGYSSLAYLKRLPLAQLKIDQSFVRD
                     VMSDPNDATIARTILALGSNLGLAVIAEGVETEEQYDFLAAQGCRDYQGYLFGRPLPL
                     ELFEAALAEG"
     gene            28874..30409
                     /locus_tag="P5537_06485"
     CDS             28874..30409
                     /locus_tag="P5537_06485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cryptochrome/photolyase family protein"
                     /protein_id="HRV77728.1"
                     /translation="MTILRLILGDQLNAAHTWFRAPRTDVQYVLMEVRSETDYVRHHA
                     QKVLAIFAAMRTFAAALEAAGHRVRYLKIGDTGNRQSFAGNLALVAAECGATRFERME
                     ADEWRVERVLDEAAQKLGLPHAVVDSEHFLADRAELARRFAAKVPRMEFFYRDMRRRH
                     RILVDTDDAPVGGVWNFDAQNREKWPGDPPAPAWPWGGHDLSGLWDEIVAAGVETIGS
                     AHAENLLWPLSRREARAGLAHFIAHALPWFGPYQDAMSTRSTTLFHSGLSFALNVKLL
                     HPREVIDAAVTAWQAGTVELASCEGFVRQILGWREFVRGVYWARMPGYAQGNALDARR
                     PLPAWYWTGRTKMACLRHAIGQSLDTAYAHHIQRLMITGNFALLAGCDPDEVDAWYLG
                     IYADAFEWVEMPNTRGMSQFADGGVIASKPYAGAASYIGKQSDYCKACAYDAKRRHGG
                     SGKPACPFNSLYWDYLLRHEARFARNPRMAMPYKAWAKMDATERAATLAQAADYLGKL
                     DEL"
     gene            complement(30675..31709)
                     /locus_tag="P5537_06490"
     CDS             complement(30675..31709)
                     /locus_tag="P5537_06490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low specificity L-threonine aldolase"
                     /protein_id="HRV77729.1"
                     /translation="MQPIQHFASDNYAGVCPEALAAFVAANAGHAPAYGEDEWTRKVS
                     DRLRELFETDCDVYFVFNGTAANSLALASLCQSYHSVVCHELAHVETDECGGPEFFSN
                     GSKLLPAHGAYGKLTPAAVLEVISRRSDIHYPKPRVVTLTQSTEVGTVYRPEEVAAIA
                     ACAREHGLRVHMDGARFANAVASLGVAPAEITWKVGVDVLCFGGTKMGLPVGEAVVFF
                     DRRLSEDFAYRCKQSGQLASKMRFLSAPWLGILEDEVWLKHARHANAMAQRLASGLMQ
                     VPGARLMFPVESNGVFCELPPAVLDGLRARGWRFYTFIGAGGARFMCGWDTLPASVDA
                     LLADVRALAG"
     gene            complement(31717..32955)
                     /gene="sstT"
                     /locus_tag="P5537_06495"
     CDS             complement(31717..32955)
                     /gene="sstT"
                     /locus_tag="P5537_06495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HRV77730.1"
                     /translation="MTTATPTALQRLLRMSLISQIAIGLVLGVALALIAPGATKSVAL
                     LGDLFIAALKAVAPILVFVLVAAAIANHKQGQPTHIRPVLMLYLLGTFAAALVAVLAS
                     FAFPTTLVLDAPAAAGNPPGGILIVLKNLLLSAVSNPVRALMEANFIGILAWAIGLGI
                     ALRHAGEGTRKVLNDLADAISQIVHVVIRFAPLGIFGLVAATMGEAGLDALLGYGKLL
                     LMIVGCMVFVALVVNPLFVFWKLRTNPYPLVFTCLRESGVTAFFTRSSAANIPINLEL
                     CRRLGLHEDTYSISIPLGATINMAGAAITISVMTLAAAHTLNIPVDFATALLLCIVSS
                     LAAAGVSGVAGGSLLLIPMATALFGISADVAMQVVAIGFVISVVQDSAETALNSSTDV
                     LFTAAACAAESGEPLNLDRA"
     gene            complement(33105..>33386)
                     /locus_tag="P5537_06500"
     CDS             complement(33105..>33386)
                     /locus_tag="P5537_06500"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HRV77731.1"
                     /translation="PEQVENAAEIGLEHNLGLTCDPVGGLVQVPCIERNAMASIKAIN
                     AAQLALRGDGAHTVSLDQVIRTMRDTGRDMLDKYKETSRGGLAVSFPEC"
BASE COUNT         4830 a        12063 c        11654 g         4639 t
ORIGIN      
        1 tccttgttga aggcgatgat cgcgatgtag ccgtagtaca cgaccatcat gatcatggtc
       61 aggatccagc cgaagctgga gcgcgtgccc accagttttt gatacttggg gttggcagcg
      121 attttggccg ccatatcgtt ttccatatct ccctccttcg tcgatgaaag gaccggacgc
      181 tcgcccggtt gcgcgcacct taggagcgga gacttacatt ccgcttacgc gcacataaaa
      241 atttcttttc caacagatac ttaacggatc cttgcataaa gcttgcacat tctccccgaa
      301 ttccatccgg atgaacagga caagcggatg ctcggatcgg tcttgagcac caggagggaa
      361 ccgaagggga cgtgcccgcc tcaggcgggc acgaaggccg cgaagaccgc gggcagcggc
      421 gcgtgctcca ggctgcgctg ggtgaacagg aagcgcccat cgcagacgaa gccgagatcc
      481 tcccagtcga ccgcgttgag cgcgtcgcgg aaggcctcga tgtccacatc ggcgcggcgc
      541 gggaagaccg ccagcaccgc gccgtcgtag tcggtgcagg ggtggatgaa gaagggcttc
      601 gccacccgcg tcttgccgtt cacatacacc cgcggctgcg cgctgcggtg gtgcaggcgg
      661 ccccacatcc accagttgga ttcgtcgaag cgggtgacct tgcgctgcag caggcgcgcc
      721 ttgtgcggcg ccagcaccgc cggcggcgga tcgcccggct cgctccagat catgcgccgg
      781 gtgaggccgc tgccgaccgt cgacgagcac acgaagtcgc ggttgccatg caccgcgtcg
      841 gcgaacagct cgtcggcgcc cgacaccgcg ccgaccttga cgaaggcgac gtcggccagg
      901 cgcagcgggt agtcgccgcg ggcgaacatc aggtggccgc cggcctcgac gaagtggcgc
      961 tcctcccacg ccggcgccgt cagcccggcg gcgaggtcgt cgccgacgcc gagcgcgcag
     1021 tagcgcatcg cgcgcgcgct gcggcccttc tcgaagcgcc agatcaggca gttcggcacc
     1081 gcgtcgtcga acacgcgcgc gtcgccgagc tcgatcgcgt cggtgatcga gccggattcg
     1141 accagcaggc ggttgagctt taccgccgag gtggccttga ggaagtcgcg cggggtgatg
     1201 aagatcagct cgccgcccgg acgcaggtgg cgcaggcact tggcgatgaa gaacaggtag
     1261 aggttggcgc gcccgtcgag gagttccccg taggcgccgc gctcgatcag cgcccgcgtg
     1321 ccctcggcga tgtcctggat gcgcacgtag ggcggattgc cgatgatggt gtcgaagcgc
     1381 tcgcgctcgg ggtaggcgaa gaagtcgatc gcctgcgcgc ccggcgggca atggtcgggg
     1441 tcgagctcga tgccgaccgc gcccggcagg tggcgcagga aggcgccatc gccgcacgag
     1501 ggctcgagca cacggccggg gttgcgacgc agcgcgacca tggcgcgtac taccggctcg
     1561 ggggtgaaca cctgaccgag cgcggcgacg tcgcgcagtc caaggggaag ctggagcggg
     1621 ggtggaacaa gggagggcgg catgggccgg aatgttacca gccgacgacc gggcacagcc
     1681 gccattgcct atacttcgac ggctggaccc cacccacccg aggagaacga caacgatgtc
     1741 cacctggtac cccgacaacg ccgaatccat cggccgcacc ccgctggtgc gcctgaaccg
     1801 cgtgctcgac ggcgcgcagg ccaccgtgct ggccaagatc gagggccgca acccggccta
     1861 ctcggtgaag tgccgcatcg gcgccgcgat ggtcaaggac gcgatcgccc acggccgcct
     1921 cggcccgggc caggagatcg tcgaacccac cagcggcaac accggcatcg cgctcgcctt
     1981 cgtgtgcgcc gcgcgcggca tcccgctgac cctgaccatg cccgagacca tgagcgtgga
     2041 gcgccgcaag ctgctggtcg cctacggcgc caggctggtg ctgaccgaag gccccaaggg
     2101 catgaacggc gccatcgcca aggccaggga gatcgtcgac agcgaccccg gccgctacgt
     2161 cctgctgcag cagttcgaga accccgccaa cccggcgatc cacgagacca ccaccggtcc
     2221 ggagatctgg aacgacaccg acggcggcat cgacatcctg gtgtcgggcg tgggcaccgg
     2281 cggcaccatc accggcatct cgcgctacat caagcgcgtg cgcggcaagg acatccagtc
     2341 gatcgccgtc gagcccacgg ccagcccggt gatcagccag accctcgccg gccagccgct
     2401 cacgcccgcg ccgcacaaga tccagggcct gggcgccggc ttcgtgccca aggtgctcga
     2461 cctgtcgctg atcgacgcgg tcgagcaggt gacgaacgag gacgccgtgc tctacgcccg
     2521 ccgcctggcg cgcgaggaag gcatcctcgc cggcatctcc tgcggcgcgg cggtcgcggc
     2581 cgcggcgcgc atcgccaagc agcccgagaa cgccggcaag accatcgtgg tgatcctgcc
     2641 cgactcgggc gagcgctacc tgagctcgat cctcttcgag ggcctgttcg acgagaaggg
     2701 catcgcgatc tgaccaagcc atgacgatcc gcgtgcgccg cgcgtacgac ccgcccgcag
     2761 ccggggacgg ctgccgggtg ctggtcgatc gcctgtggcc gcgcggactc gcgcgcgaga
     2821 acgcacgcat cgagcactgg ctgcgcgagc tcgcgccgtc gcacgaactg cgcaggtggt
     2881 tcgcccacga gccggcacgc tgggacgaat tccgcctccg ctacgccgac gagctgcgcg
     2941 cgcccgccac cgccgcggcg ctcgccgagc tgcgcggcct gctcgccgca caccccgtcc
     3001 tcaccctgct ccacggcgcg cgcgacacca cgcacaacaa cgccgaggcg ctgcgccagt
     3061 ggctggcgcg cggtggtccc tcctgacccg gcagccgccg ggcgctcccg gacccctcgc
     3121 gctcgcatcc agtatcgcgt gcgcacgact gtaatccggg ctgcgtgata ctctgcattg
     3181 tgcagtgcac aacccgatcc cgtggcttgc cgcacgggcg ccaccgggtt cccgtgctgt
     3241 ccgtccggat ccggaggggg tgtcgatgtt tcgcttgcca tggtcaacca cgaaaaacgc
     3301 ttccgccccc ctcgccctcg cgctgcaggg cggtggcgcg catggcgcct acacctgggg
     3361 cgtgctcgac cgcctgctcg aggcgggcgt tcccatcgag ggcatcagcg gcaccagcgc
     3421 cggggcgatg aatgccgtgg cgctcgccga gggctggacc acgggcggcg cggatggcgc
     3481 acgcgccgcg ctcgaccgtt tctggacggc cgtcggcgac agcgttccct tccacctgga
     3541 gctgctgcac aacctcaatc cctcgggaga cggcagcctc ccctcgccga tgaacgtgat
     3601 gctcgggctc gcgcgcgtgt tctcgccgta ccagctcaac cccttcgacc tcaacccgct
     3661 gcgcgacgtg gtgcgcgcgc agttcgactt cgagcgcatc cgccgcgcgt gcccgctcaa
     3721 gctcttcatc gccgccaccg ccgtgcgcac cggcaaggtc cgtctgttcc gcaccgccga
     3781 gctcggcgaa gcagccgtac tggcctcggc ctgcctgccc accttgcacc acgcggtgga
     3841 gatcgacggc gagcactact gggacggcgg cttcaccgcc aacccggcga tctacccgct
     3901 gctctacgaa tgcgacacgc cggacctgct gatggtgctg ctgaaccccc tgcagcacga
     3961 gcacgccccc cgcagcgccg cagaaatcgc cacgcgcagc atggagctcg gcttctccac
     4021 gaccttcctg cgcgaaatgc gcatgatcgc ccacgcccgc cagttcatcg ccgagcgccc
     4081 gcgttggtcg ccgatcggcc gcctcgagcg caggctgttg cacgagcgct ttcacctgat
     4141 cgacgcaccc gaactcggcg atgccggcag cgcgagcaag ctcgatgcca ccgccagctc
     4201 gctgctccgg ctccgcgaac tcggccgtgc acgcgccgag gcctggctgc agatacatgc
     4261 caacggggtc ggccggcgcg aaacgatcga cgtcggcacc ctgttcctgt gagactcgtc
     4321 gccccgtggc gtctcgctaa ggtgtttcca gcccgttcca ggcctcgctt gcactcgcat
     4381 agaagtgcgc ggggatgcgc cgcttctcga gctccacgcc gagcttcatg cgcaggaagc
     4441 cgttcgcggt gtagcgggtc acggtgtgat agtgagtatc catcaggccc ttcaccatcc
     4501 cgacgtagtc gtccaccagt tccggcacga tcgagaagcg gtcgtagttg accaccgcat
     4561 ccaccttgcg cccgagcgga gcgagcgcgg cgcttacggc gtcgcgaatc gcggcgatgt
     4621 cctgcggcgt gcgcaccgac agcccttcga agtcgacaaa gaacacgtcc tgctgcgcgt
     4681 cgtaggccag ccgccgctcg agcggaacgt cgagcaggtc gtggcgcaag cccatcggcg
     4741 cgtcgacgaa gatacgcgca tccatcagga cgggcggggc cttcatcacc ggcacgaagt
     4801 ccatgcggtc gaggatgtcg cgctggagat cgacgccggg cgcgatctcg atcagctcca
     4861 gcccctcctc acacaggcgg aacacacagc gctcggtgac gtagagcacg tccttcttcc
     4921 atttcaccgc ctgggcgccg ctgaacgtgc ggtgctcgac cgcgtcgacg aacttcctcg
     4981 ccgcgccctc gcgcacgatg cgcaggcgtc cgtgctccac cgccacctcc agcccgcccg
     5041 cgctgaaggt gccgacgaag accaccttcc tggcgttctg cgagatgttg atgaagccgc
     5101 cggcgccggc gagccgcgga ccgaacttcg atacgttgag gttgccctcg cggtcggcct
     5161 gggcgagccc gaggaaggcg acgtccagcc cgccgccgtc gtagaagtcg aactggctgg
     5221 gctggtcgat gatcgcctgg gtgttcaccg ccgctccgaa gctcagcccg ccggcgggaa
     5281 tgccgccgac cacgccgggc tcggcggtga gcgtcagcag gtcgatgacc ttttcttccg
     5341 cggccacggc cgcgatccct tccggcatgc caatgccgag gttcaccacg gcatccgact
     5401 gcagctccat cgcggcccgg cgggcgatga tcttgcgctc gcccatcggc atcgcacaga
     5461 tcgtcgacat cggcacgcgg atctcgccgg agaaggcggg gctgtactgc tcggcgtagg
     5521 tctgcatgtg gtgctcgggg cgatccgcca ccaccacgca gtcaaccagc acgccgggca
     5581 cctgcacctg gcgcgggttg agcgagccgc gctcggcgat gcgctcgacc tgcacgatga
     5641 cgatgccgcc cgagttgcgc gccgccatcg cgatcgcacg cgcctccagg gtcagcgcct
     5701 ccttctccat ggtgacgttg ccgtcggggt cggcggtggt gccgcggatg atgccgacgt
     5761 ggatcgggaa ggccttgtag aacaggtagt cctcgccgtc gatcggcatc agccgcacca
     5821 gatcctcggc ggtgcgcgcg ttgagcttgc cgccgccgaa gcgcggatcg acgaaggtgc
     5881 ccagccccac ccgggtgagc gtgcccggct tgcccgccgc gatgtcgcgg aacaggtgcg
     5941 agatcacccc ttgcggcagg ttccaggcct cgatgcggtt atccaccgcg agcgcctgca
     6001 ggcgcggcac caggccccag tggccgccga tcacgcgcgc caccaggccc tcgtggccga
     6061 ggtggttgag gccgcgcgtc ttgccatcgc cctgcccggc cgcatacacc agggtcaggt
     6121 cgcgcgggcc ggcaagggca ccctcggcct ccaggaagcg ttgctcgagc gcgatcgcca
     6181 cgctctcggc aaagccgatg ccgacgaagc cgccggtggc gaccgtgtcg ccgctgcgga
     6241 tcaggcgcac cgcctcgcgc gccgacacga tcttgccggt gtcggcggcg cgcagcgagg
     6301 ccaccatcgg gtgcgttttc cttgccatgg cggatctccc tttcgccgcg cccgcatgcg
     6361 gacgagccgc aaccggggat cgacctcccc tttcttgtac ggcgaacgaa aagattaccg
     6421 catccgcagc cttcgagccg gaagccgcgc cccccgcggt gcggaccccc tggtcaacgc
     6481 cacatgtcgc gcatcttcgc ggcgaggtcg atcgcggcct ggcgcgaggc cggcgagccc
     6541 tgcagctcgg gcgccggtgg cggccagctc gcctgctcga agcgcccgag caggcggttg
     6601 gggatgaagc ggctgcgccc ggcatacaca tggcgatcgc ccagacccat ctgctgggtg
     6661 acgtggaagc gctgcggcac gatcaggtcg agggcgtcct tcgcgcgcgt catcgccacg
     6721 tagaggaggc gacgctcctc ctcgatctcg gcgctgttgc gcgtggcgac gtccgacggg
     6781 atgcagccgt cgaccacgtt gagcacgctc accgcgctcc actcctggcc cttggccgag
     6841 tgaatggtcg acaggatcag gtagtcctcg tcgagcagcg gcatgccggc ctcgccgctg
     6901 gtggcgctgg gcgggtcgag cgtgagctcg gtgaggaagc gctgccggct cgggctggtg
     6961 gcggcgatgc gtgcgagctg ctggatgtcg agcgcgcgga cctggaagtc gtcgtacagg
     7021 cgcggcatct gcgcctcgta ccagcggcag gcgagctcga agtcggccgg ccacggcaac
     7081 ccgcccctcg ccccgccaat cgccgtattc gcgcctgccg gcgctcctac atgagcttcc
     7141 ggaagcggcg cggtttctgt aggagcgccg gcaggcgcga atgcggcgct cgggacgttc
     7201 ccacgcatcg cctccccttc gcccgtgttc gcggcttccg ccgctcctac atgagcttcc
     7261 ggaagcggcg cggtttctgt aggagcgccg gcaggcgcga atgcggcgct cgggacgttc
     7321 ctgcgcatcg cctctccatc gcccgtannn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7441 nnnnnnnctt ccggaagcac ggcggtttct gtaggagcgc cggcaggcgc gaatgcggcg
     7501 ctcggggctt cctcccgccc ggcgagccgg tcgagcagcg tggcgaactc cagccagccc
     7561 gcgcgcgccg cctccggcac cggctgctcg gcgagcagcg cgcagcccgg cggcgcggcg
     7621 cagacgttgt cgagcacgcg cccggcggtc ttggggccaa tgccggcgag gagctggatg
     7681 gcgcggaagc cggcgatgcg gtcgcgcggg ttctcggccc agcgcagcag cgcgagcacg
     7741 tccttgacgt gggcggcctc gaggaacctg agcccgccgt acttcacgaa gggaatattg
     7801 cgccgggtca gctccagctc caggcgcgcg ctgtgcgccg aggcgcggaa cagcaccgcc
     7861 tgctgcttga gcttgagccc ttcctcgcgg cgcgccagca cgctgtcgac cacgaagtcc
     7921 gcctgcgccg cctcgtcctt caccgtcacc aaacgcgggc gctgcgccga ggcgcgctcg
     7981 ctccacaggt tcttggcgaa gcgctcggcg gcgagcgcga tcaccgcgtt ggcggcgtcg
     8041 aggatgggct gggtggagcg gtagttgcgc tccagcgtca ccacccgcgc cggtggcgcg
     8101 aaggccgccg ggaagtcgag gatgttgcgc accgtggctc cgcggaaggc gtagatcgac
     8161 tgcgcgtcgt cgccgaccac ggtcaggcca cggccatcgg gcttcatcgc gagcaggatc
     8221 gtggcctgca gcgcgttggt gtcctggtat tcgtcgacca gcacgtggtc gaagaggccg
     8281 ccgatctcgg cgccgaggcc gggatcggac accatctgcg cccagtacag cagcaggtcg
     8341 tcgtagtcga gcacctgctg ggcctgcttg gcgtcgacgt aggcgcggaa caggcgcttg
     8401 agcgcgtcct cccactgcgc gcaccacggg aagctcgcct gcagcacctc ggcgagcgcg
     8461 gcgcgcgtat tgaccaccgc cgagtagatc gccaggcagg tgcccttctg cggaaaacgc
     8521 tgcttcgtcg ccgacagccc gagctcgtgg cgcaccaggt tcatcaggtc ggcggagtcc
     8581 tcgcggtcgt ggatgctgaa gccgggatcg agcccgatgc ggccggcgta gtcgcgcagc
     8641 aggcgcgcgc cgatggcgtg gaaggtgccc gcccacggca gctccgcgcg cgccaggccg
     8701 gggcggtcgg cggcggcctg cgcgaggatg cggcgcacgc gccggcccat ctcgtccgcg
     8761 gcgcggcgcg agaaggtcag tagcaggatg cgcccggggt cggcgccggc ggcgaccagg
     8821 cgggcgacgc ggtgcgcgag cgtgccggtc ttgcccgagc cggcgccggc gatcaccagc
     8881 agcggcccgg cgtcgatgcg gccctcggcg ccgatgccgt gctcgaccgc ggcgcgctgg
     8941 gcggggtcga gcgcggcgag cggattggcg gccgccagtt gcggggcatc ggctccggcg
     9001 cgggacgcgg agtggggctc ggagtggggc ccgggaaggg tctcgatggg ggtcaccatg
     9061 gctgtaagta tattcagccc cgacgcgcgc cgatagccgt gacggcggcg ttcgttccag
     9121 aatgggcgcg acaccgaccg accaccggag acccgcgatg cccgcccccg acccagtcct
     9181 gccgagctgc ctgcagccgc gccgcgtgat cctcttcagc ggccacatga tcgacgcgcc
     9241 cggccgcacc gagccgcgct tcccgcccgc gctcgcgccc gcggcggcgg cgcgcatcgc
     9301 cgccgcgctc gatgatctgg gggccggccc gctcgacctc ggcctcaccc agggcgctgc
     9361 cggcggcgac ctgctgttcg ccgaggcggc gcaggcgcgc gcgctgccgc tgctgttcct
     9421 gcagcccttc ggcgaggacg agttcctcgc gcgctcggtg cgcccggtga gcgagggcga
     9481 gcaatgggtg gcgcgttacc gcgcggtcgc cgcccgcctc gccagcccgc cgcgcgccat
     9541 gccgcccgca gccgctgccg aagaggccga caaccccttc gagcgctgca accgctggct
     9601 gctcgacact gcgcttgcct gcggcggcga ccgcgtctgg ctgctgtgcc tgtgggacgg
     9661 gcaccgcggc gacggcgccg gaggcaccgc gcacatggtc gaggaggtca gccgccaccg
     9721 cggccacgtc ctccacatcg acacccacga cctgcaagca cacgatcccg ctggcagccg
     9781 ccccgatgct ggactagcct gaatcgagcc gggcacgtcc gtgctcgcca tccggacgtc
     9841 cagcggagaa tccccatgag catcccgcgt ttccgcctgc gcggcagcat cgcgcccacc
     9901 ccacccgctt catccgcttc aaccgctgca acgcccgatg acggcctggt cgcgatcgcc
     9961 tccaggcgca cgctgatccc cgggcgcgca cgcgacggcg tgagcggcga actcgaggtc
    10021 gccggcgacg aggtggtccg cgtcgagctc gacaacggct tcgtgctgtg gacccgcgcc
    10081 gacgccctgg tacgcgagca cggccgccgc agccgcgccc gcgacggcgg cgacgcctgg
    10141 gagatcgacg cgctggctcc ctcggccaat gcggccacgg ccgagcgcgg cctgctcggg
    10201 ctgggcgtgc gcgtgctcga gttcttcggc gtgcgcgtca aggagggcgc cgcgcgcaag
    10261 ctcggcgagc acttcgagga gcgccagctc aagccgcagc cccccggcct gcaccgcgtg
    10321 agcctcgccg accgcttcgc gctggcgccg ctcgcggcgg acgccaagct gcccggcggc
    10381 gggccgctgc tggtcttcct gcacggcacc gcgtcgagct gcgagggcag cttcggcaag
    10441 ctgtgggatg cgggcaacgc cgccggcgcg gccgcccgca cccgtctcgc tgccgcctac
    10501 ggcgagcgcg tcttcgccct cgaacaccgc agcctcaccg agagcccggt cacgaacgcg
    10561 ctcgcgctcg cgcgccgcct gccgcaggac gccgagctgc acctggtcag ccactcgcgc
    10621 ggcggcctga tcggcgagct gctctgcctc ggacagtgcg agggcgtgcg ccgcctgctc
    10681 gacgccgagg gcctgcacac cctgttcgcc gccgaccgca cgatcgccga gcagctcggc
    10741 ctgcagccgc tgtcgcccaa ggaggcgaag gcgcgcgacc acgcctacga tgccgaccgc
    10801 gcggcgctcg ccgagctcgt cgagctgctg gtcgagcgca aggtccgcgt cacccgcttc
    10861 gtgcgcgccg catgcccggc gcgcggcacc acgctcgcct ccggccgcct cgaccgctgg
    10921 ctgtcgatgc tcgacttcct cgccgggcgc gcgctcggcg gcggcctgtt cgccgacggc
    10981 ctcgacttcc tgctcgcggt ggtcaaggag cgcaccgacc cgcgcaccct gcccgggctg
    11041 gaggcgatga tgcccggctc ggcgctgacc cggctgctgc accaccccga cctcgtcacc
    11101 gccgccgacc tcagcgtgat cgccggcgac gcggagggcg acacggtgtg gcagaagctc
    11161 aagctgctcg tcaccgactg gttctacggc gccgaccacg acctcgtggt caacaccggc
    11221 tcgatgtccg gcggcctgcg ccgccccgac ggcggcgcgc gcttccgcct cgaccgtggc
    11281 gcgcgggtcg atcacttcag ctacttccgc aacgccgaca gcgtgggctg gctgctcgcc
    11341 ggcctgaccc gcggcgacca cgaggacggc ggcttccgcc ccctcgccga ggcgccgcag
    11401 acgccgccgc gctggcgcga ggccgtgcgc cgtgcgcgcg gcggcggccc gcgtccgctc
    11461 accgtcatgc tgccgggcac catgggcagc gcgctgagcg ccggcgggcg ggcggtgtgg
    11521 ctgcactact tcaccttgct gcgcggcggg ctcggcaaga tcgaactcgg tgcgcgcgag
    11581 gtctcggccg acgacctgct cgacgacttc tacggcccgc tgctcgagtt cctcgccgaa
    11641 caccaccgcg tcgagatctt tccctacgat tggcggctgt cggtgcgcgc cgccgccgcc
    11701 cgcctcgccg cggcgctcga aggctggctg ccgcaggccg agcgcgaggg ccagccggtg
    11761 tatctggtcg cgcactccat gggcggcctg gtggcgcgcg cgatgatcgc cgacggcgga
    11821 cgcggcgccg cggtgtggca gcgcatcacc cgcctgcccg gcagccgcct gctgatgctg
    11881 ggcacgccca acctcggctc ctacgaggcg gtgcgctggc tcaccggctt caaccccacc
    11941 caggcccgcc tcgcgctgct cgacttcacc cgcagcaccg ccgaggtcgt cgatctggtg
    12001 cgcgagtatc ccggcctggt cgagctgctg cccttcgccc ccgaggaccc cgacttcgcc
    12061 gacccggcgc ggtggacgct gctgcgcgag tcgctccagg cacagtggaa gactccgccc
    12121 gccgaagccc tgcgcagcgc gcgcgagacc tggacccttc tgcgcgcggc gccgcccgag
    12181 ccggcctaca tggcctacgt cgccggctgc cagcgcgcca cggtgatcga ctatgagctg
    12241 caggaccacg acgaggacag ctggctgtcc ggccgcaagc gcatcgcctt catcgccggc
    12301 cgcgagggcg acggcacggt gagctgggcc tccggcctgc ttcccggggt gccgacctgg
    12361 tacgtcgacg acaccgccca cgacgccctg tgcgtgcagc gcaaggcctt cgccggctat
    12421 ctcgacatcc tcgccaaggg cgccaccacc cgcctgccga gcgcgccgcc gcagcgcgcg
    12481 cgcgcactcg ccgacgagcc aacgcgcttc gagctgccgc cgctgccgcc ggcggacggc
    12541 atccccgcgc cgtccgagct gcgcagcctc ggcttcggcg gcggcgtgcc cgcgagcccg
    12601 ccggaagccc gtgccacgac accgccgatc gagctctcgg tccgccacgg cgacctgtcc
    12661 tacgcgcgct tcccggtgct ggtggggcac taccgcggcg acaccatcgt cagcgccgag
    12721 gccgcgctcg accgtcgtct cgacggcgcg ctgtcgcgcc gccaggcgct cggcctctac
    12781 cccgggcagc acggcagcag cgcgcagttc ttcaacccgc gtcccgaggc gcgccccgcc
    12841 ggcgcgatcg tggtcggcct cggcgaggtc ggcgagctca ccccgggcct gctcgaggcc
    12901 ggggtgcgcg gcgcgctcct cgaccacgcc ctgcagatcg cgcagtggcc ggacgagcgc
    12961 ttcggccccg ccggcggtcc gcgccgggcc tcggtgtcct gcctgctggt cggcaccggc
    13021 gccggcgcgc tgtcggtgcg cgactcggtc gaggcgatcg tgcgcgcggc gatcgccgcc
    13081 aacgcgcgcc tgcacgagac cgagctcgac ggccgggtgt ggatcgaccg catcgagttc
    13141 gtcgagctct tcgccgatgt cgccatcggc gccgcagaga gcctgcaggc ggtgctggcc
    13201 atcccgcagc tcggcgccgc ggcgcgctgg ccggcacagg ccatcgaggc cgggcgcggt
    13261 gggcgcgtgc gggtgcgctt cgacgaggcg ccggagtggt ggcagcgcct ggagatcatc
    13321 gaggacgagg gccggcgcga cagcctgcgc ttcatcttcg tgaccgaccg cgcgcgcgcc
    13381 gaggagaccc tggcgagcgg ccagctcgca ctcgccgacg ccttcatccg cgaggccgcg
    13441 gcctcgccgg cggccaaccc cgaggccgcc ttcacgctgc atgagatgct gctgccggtg
    13501 agcctgcgcg aggccgcatc gcgccagggc aacctggtgc tgctggtcga tccgcgctcg
    13561 gcgcgctacc cctgggagct gctggagaac cgctggagcg acagcggccg cccgccggcg
    13621 gtcgccgccg gcgtggtgcg ccagatccgc accacccagt accgcacccg accggtgcac
    13681 gcggacgaag ccagcatcct ggtggtgggc aaccccgacc tcgacggctg ggaggacttc
    13741 cccgacctgc ccggcgcgcg cgccgaggcg agcgaggtcg ccgaatgctt cgagactgcc
    13801 ggctggcggg tggagcgctg catcgatccg cccacccacg aggtcctcgc cggcctgcat
    13861 cgcaacccgt ggcgcatcct ccaccttgcc ggccacggcg agcacgactt ccccctgccg
    13921 caggccaggc gcaaacccgg cgatccaccg gccgcggaac cgcagaccgt atccggcatg
    13981 gtcatcgggc gcgacacctt cctcaccccg ggcgacgtcg agcagatgcg ctgggtgccc
    14041 gagctggtct tcatcaactg ctgccacctc ggcagcatgc gcggcagcga caagggcgcg
    14101 ctcgccgcca acctgggcat gcagttcatc aagatgggcg tgcgcgcggt ggtcgccgcc
    14161 ggctgggcgg tggacgatgc cgccgcgctc gccttcgcca acaccttcta ccgcctgatg
    14221 ctcgccggcg aaaccttcgg cgaggcggtg cgcgccgcac gcgaggaggt ctggctgcgc
    14281 taccgcgggg tcaacacctg gggtgcctac cagtgctatg gcgacccgtc ctacaccctg
    14341 ctgcgcggac gacccgcgcc gcggccgcag gcgcgccgct tccactgccc gaccgagctc
    14401 ggcgtggaac tcgacaacct cacccaggcc ctgcgcagca gcgccgggga cgacgctgcg
    14461 gcgcgcatcg ccgcgcttct ggaaggcatc cccgaaagcg cccgcgaagc gtggctcgcg
    14521 cgtgcggacc tgtgcgccgc gctcggcttc gcctgggcag aggcgcgcgc ctggcccgag
    14581 gcgatcgagc agctcgatcg tgcgatccgc gccgccgccg gcgattgccc gctgcgcgtg
    14641 ctcgaacagc tcgccaactg ccgcgcccgc ctcgccgccg acgaggcctt ggccgcgcac
    14701 cggcgcggcg cagctgcgga caccgcgcag gcgaaggcgc gcgaggagct cgttcaggca
    14761 gcgctcgccg agctcgagcc cttgtgcagg cgtgcaccca ccgtcgagcg cctgagcctg
    14821 ctcggcagca cgcacaagcg ccacgcgctc gtcgccgccg cgccggcagc ccgcctggag
    14881 gcgctcgacg cctgcgccga agcctaccgt gaggccttcg aagccggcgg cagccaggac
    14941 gcctacccgt tcaccaactg ggcgagcgcg gtgctgctcg cagcgcatct cgacactgcc
    15001 catccggggc tgccgccagc cgcgctggaa gaggagctcc cgcgcctgcg caccagcctg
    15061 caggagggtg ccgggcgcag tcccgacttc tggaccgcag ccagtctggc cgacctcgac
    15121 ctcgtgcagc tgctcgcgtg cagcctgcac ccggccgagc ccgccgcgcg cggccgcaag
    15181 cgtgccgccg cgacgaccga ggcgtgcgcc gcgctcgccg ggcagatcct cgccacctac
    15241 cgcgatgccc tcgcccgcgg cgccagcccg cgcgaacgcg cctcgctggt ggagaacctc
    15301 gacgccttgc tcgtgctgct ggaaggcggc ccgcccgttc tcggtgaacg cctgcggcag
    15361 atccgcgacg caatctgagc accccgcccc cgggaggggg cgggcgggcc gctcaggcgc
    15421 gcacgccccc gcgcaggaag cgcccggtgt cgaggaagtg cagggtctgg atcaggcagg
    15481 cgcgcgacca cagcatctgc atgtgggtca ccggcagcac ggcatggtcg cgcgcgcccg
    15541 gccagcgcgt ctcggccacc gtcaccatgc cgtcattggg cttctccatg ccgggcacga
    15601 tgcgccccat gccgaccggc cggttgccgg cgacgacgcc gatctcgtag ccgggcggca
    15661 cctcgggcag cggccgcgcc agccactgcg gcagcactcg tccaagcgcg ccgcgcagca
    15721 ccgggacgcg caggatgcgc tcgcccgcat acgagccgca gcacggcggg ccaagcagga
    15781 ccacccggcc gatgccttcc ggatgatggc gggcgagcat gttcagcacc acgcaaccgc
    15841 ccaggctgtg cccgaccaga tgcagcggcc ggcggccgag ggcggcgatg tacgccgcca
    15901 gctcgtccgt cgcgccgtcg agcgagccga gcagcgaatg ccaggaaaac acccggctct
    15961 cgcgccccat gcggcgcagc tggcggcggt gcgcggaaaa caccacgccg tgcatccaca
    16021 ggccgtggac gaagaggatc agcggcttct cggtctgcat cgcggcacgc tcagttaccc
    16081 ttcagctgcc gcgcggtcag cgcaggattg tcgccgctgt aggcggcctt gatcgcgtcc
    16141 caggcctcct cggcggtctc ggcgtagtgg aacaggttct tgtcctccgg gctgatcacg
    16201 ccatgctcga ccagcacgtc gaagtcgatc aggcgctgcc agaagtcgcg cccgacgagc
    16261 acgatcgggc ggcggcggat cttgcgcgtc tgcgtcagcg tcagcacctc gaagagctca
    16321 tccagcgtgc ccaggccgcc gggaaagctc accagcgcca ccgcgcgcat caggaagtgc
    16381 atcttgcgga tggcgaaata gtggaactgg aaacacagct cgggcgtgat gtaggggttg
    16441 ggcgcctcct cgaagggcag gaagatgctc atccccatgc tgcgcccgcc ggcgtcgaag
    16501 gcgccgcggt tgccnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnagcagc
    16621 tcgagctgca gccgcaccgg gcgcagctcc tcgcgcagca ggaagtcggt gtcggtgaag
    16681 gccatgcgga aggaactgcc ggggccgtca tagcggccgt ggggctgggc ggccttggcc
    16741 tcgtcttcgg cggaggggaa gttgcgggcg cgcagggggg tgttcttgct catcggaaaa
    16801 tccatccggt tcggggaccc gcatcatcgc atccgtgcgt gacaggacgc gagcccccgc
    16861 cgcgccgagc ggacgatcag tccccgcccg ccatcgcctc gccgaaggcg cgcgcgcagt
    16921 cgaggaagcg cgccaggcag ggattggcat tgttcggagc ccagatcacg ccctgctcga
    16981 tcacccgcgg cgacgagatc ggccggaaca ccgcgcccgc cagctgcatc cggctcatcg
    17041 agcgcggcac cagcgacacg ccgagcccct ccgccaccag gttgacgatg gtctgctgca
    17101 ggtgggtctc gagccggata cgcggttcga agccgtgctc gcggcagcac ccggccacca
    17161 gcgcgtgcag cgccggcgcg gtggcggcgg gaaaggtgat gaagggttcg tcggccagct
    17221 cgcccaccgc gaccaccgca gcggccgcga gcgggtggcc ggcaggaagc accgcccaca
    17281 gcggttccgc atgcaccctc aggtactcca gcccgtcggg gcgctgccac gggaaggcaa
    17341 tacccacatc ggcgcggccg gagagcaggg cctcgtcgag ctcgcgcggc accacctcgc
    17401 tcaactggat ctcggcggcg gggaaggcgt cgccatagcg ccggatcagc gccggcagga
    17461 cgttccacgc cgcgctcatg gtgaagccga cgcgcagcac gccgcgttcg ccgcgcgcgg
    17521 tggcctgggt gctgcgcacc gcgccatcga gcgcagcgag gacgcgcacc gcgtgctcgt
    17581 gaaaatgccg cccggccgcg gtcagctcga cctggcgcga gctgcgcacg aacagcgcgg
    17641 caccaagcgt gtcctcgagc gcggcgatct gccggctgag cggcggctgg gtgatgtgca
    17701 gctgggtggc ggcacggccg aaatgcagcg tgtcggccag ggccacgaag tagcgcagct
    17761 ggcgaagctc gatcgtcatc gatacgcctt gagtatcaat taaagcaaga tatggaattg
    17821 gacggtatag atcgacaccc ttacgcttga ctcaacacct cgggagtcac gcgcatgtcc
    17881 gccatcgtca acgtcgtcct gcccatcttc ggcctcatcc tggccggcta cgtctgtcgc
    17941 cgcagcggcc gcctgggcga gacggcgtcg aacgagctca gccgtttcgt ggtctggctg
    18001 gcgctgccgg cgctgctgtt caatgtaacc gccaccgcga gctgggaaca gctctggcag
    18061 ccgggcttca tcgcgtcggt gtgtgccggc tgcgcgctgg tgttcgcggc aacggtggcg
    18121 ttgcgcgtgc gcaagtcggg ccggctggtc gacgccagca tcgacggcct gagcgcggcc
    18181 tacgccaaca ctggctttct cggcatcccg ctgtgcgcgc tggtgttcgg cgacgccggg
    18241 ctgatgccgg cgatcgtcgc caccctgatc gtggcctgcc tgctgttcgc agtcggcatc
    18301 gtgctggtcg agatcggtct gcagaaggag aagcacccac tgcgcgcgct gctgaaggtg
    18361 gcgcgtgcgc tcgccgccaa cccgctgctg gtcgcgccgg tgctcggctg cacctgggcg
    18421 gccttcggtg ccgagctgcc cgcccccgcc gcgcgcttcc tgtccctgct cggcgcggcg
    18481 gcgacgccct gcgcgctggt gtcgatcggc ctcttcctcg cacagaagca cgaggggcag
    18541 cacgacggtg caaccgggct ggtgctcgcc aagctgctct tgcagcccgc gatcaccgcc
    18601 tttctcgcct tccgcgtgtt cgagctgccg gcgctgtggg caagcgctgc cctgctgctg
    18661 agcgcactgc cgaccggcac cggcccgttc atgctggcga gctactacgg ccgcgacgcc
    18721 gccctggtcg cgcgcgtgat cctgctcaca acggtggggt cggtggtgac ggtatccatc
    18781 tgcctgaacc ttctcgccaa cctggcgcca gtctgagcgc acggcgcgga cccgctcacc
    18841 ccagcagcgc caccgacttg atctgcgccc acatccgcag ccccgggcgc agcccaagct
    18901 gcgcgctcga gcgccgggtg atgcgggcga tcagcgcggt gccgccggcg tcgaggccga
    18961 ccaggacgtg ggcgggggaa tcggcgccga ccacttcctt caccgtgacc gcgatcaggt
    19021 tgacgatgct ggtgccctcc accttgtggt cggcgaggct gacgtcgcgc gcatggatgc
    19081 ggaagcgcag acggcggcca agggccacgg gctggcgctg cacccacacc gcgccgccgg
    19141 ggaaatccag ccgggtgagg tggtcgtggt cgtcatgttc ggccaccgtg ccgtcgacca
    19201 ccaccccggc atcctcggtg aaggcggtgg gcaggtcgag gcgagccatg gtggcgtgga
    19261 gttcgccggc ggccatcacc ttgcccgcac cgagcatgac cacgtggtcg gccaggcgca
    19321 cgacctcgtc gggcgagtgg ctgacgtaga gcaccgggat gtcgagctcg tcgtgcaggc
    19381 gttcgaggta gggcaggatc tcctgcttgc gacggtggtc gagcgcggcg agcggctcgt
    19441 ccatgagcag gatgcgcggg ctggtgagca gcgcgcgcgc catgccgacg cgctggcgct
    19501 cgccgccgga cagccggtcc ggcatacgct cgagcaaggc ctcgatgccg agcagcgcca
    19561 ccgcgtgctc gagccgcacc cggcgcgccg ccgtcggaat gcggcgcagc ccgaactcga
    19621 ggttgcgccg caccgacagg tgggggaaca ggctcgcctc ctggaacacg tagccgagct
    19681 cgcggcggtg agtgggcacc tggatgccgc gcgcgtcgtc ctgccagcat tcgccgttga
    19741 ccaccaggcg gccgcgcgcc gccggctcga gcccggcgac gcagcgcagc agcgtggtct
    19801 tgcccgagcc ggagtggccg aacagcgcgg tgacgccgcg cccgggcagg cgcaggtcga
    19861 cgtcgaggcg gaagccagcg tagtcgaccg cgaagcgcgc ctcgataccg gcggccgacg
    19921 gggtggggcc ttgggcggcg ccgcttgcgc cggtcgcagc gcttgcggtt gcagcggtgg
    19981 cgacagcatg tgcggcaatt gcagtgcttg cgccggttgc cagcggatgc tcggccatca
    20041 gcccacccct ccgccggcat tgccgcgccg gccgtagagc gcgagcagca ccacgaagct
    20101 gaacgccagc atgccggccg acagccagtg cgcctgggcg tactccagcg cctcgacgtg
    20161 gtcgtagatc gccaccgaga ccacccgcgt cctgtccggg atgttgccgc cgatcatcag
    20221 caccacgccg aactcgccca ccgtgtgcgc aaaaccgagg atggtcgcgg tgacgaagcc
    20281 cggccgcgcc agcggcagcg cgacgttgaa gaaacggtcc cagggcccgg cgcgcagcgt
    20341 ggcggcgacc tccagcgggc ggcggccgat ggcctcgaag gcgttggcga gcggctgcac
    20401 gacgaagggc agcgaataga ccaccgagcc caccaccagg ccggcaaagg agaacggcag
    20461 caggccgagg ccgagcgcct cggtgagccg gccgagcggc ccgttcggcc ccatcgccac
    20521 cagcaggtag aagccgatca ccgttggcgg cagcaccagc ggcagcgcca ccaccgcgcc
    20581 gacgacgccc ttccagcgcg agcgcgtgca cgccagccac cacgccagcg gcgtgccgag
    20641 cagcaacagc accacggtgc tgaccgcggc gagctcgagg gtgaggcgga tggcggacca
    20701 gtcggcgccg gtcagggtcg gcatggagcg ggcatgaaga ggggcaggat cgtcgaggcg
    20761 gcacgcccgt gcggcggcgg cccccattgt gccgcgcccg gcgcgcggat tgaaagcgca
    20821 ccgcgccccg gggggtgtcg cgacctcgaa ggtgagcggg cacccgggcg ccgaggtgtg
    20881 cgtgctccgg cgcgccaaca cgacgcaact ccgcggggcg gggtgtagga gcggcggaag
    20941 ccgcgaaccg ggcggatcct ctgcgagacg ccgcgacggg tacccgggcg cctcaattcg
    21001 cgcctgccgg tgctcctgca aaacggccgc aacccgagcc tgaattcgcg cctgccggcg
    21061 ctcctacaaa aacggcgcgg cccgagcatg aattcgcacc agccggcgct cctacagaaa
    21121 ccgatgcggg acggggcggg tgtggcgagc tgcgaatcct gtagcgccgg ggcggcgagc
    21181 agcggcaggc cccgtcagcg cccggctggc gcgggcggca gctcgaaacc gtagcgccgc
    21241 agcaccgtgc gtgcggactc gctgccgatg aactcggcga acgcgccggc gagcggcttg
    21301 ccggcggcgg cgcgggtgag catgaagccc tgctcgagcg gcgcgtgcag gctcgcatcg
    21361 atgaggtggt agccgccttg cgcagccagc gtcgggttga gcgcgagcga gagcgcgatg
    21421 atccccaccg ccgcgttgcc ggtctgcacg aactgcgcgg tctgggcgat gttctccccc
    21481 tgcaccaggc gcggctgcac cgcctcccac acaccggcgg cgcgcaaggc ctcctcggcg
    21541 cgcttgccgt agggcgcgtg gcgcgggttg gcgatggcga tgcggccgag cacggggtcg
    21601 gcgaggtcct tcagctccag gctgcgcgcg tcgcgggtcg cgctccacag cacgatgcgg
    21661 ccgagcgcgt agggccgggt cgtgccgtgg gcgaggccct cggcctcgag cgtgcgcggg
    21721 taggcgatgt cggcggagaa atagagatcg aagggcgcgc cctggcggat ctgcgtggcg
    21781 aacttgcccg aggagccgta caccacctcg acgacatcac ccggatgcgc gcgaccgaac
    21841 tcggcgacga tctcgtcgag cgcgaacttg aggtcggagg ccgccgccac cgtgacgcgc
    21901 tcgcccgccg tggcggtcgg cgcgcagacg cccgcggcga gcgcgagcag gacgccgagc
    21961 acacggcggc gtggcggcaa cctggatgaa cccatggatc cttctccctt atagagacag
    22021 tgcatcgtgc agcaaaggcg gaagcggcgg acatcggcgc gggtgtttgg cgccaccggc
    22081 gatccgatgc ccggttcgcg tggacgcagg cgatctgcgc catcgcgctc ttcagcgtcg
    22141 gattcgcgcc ttccggcgct cctacacaaa ccatcttcac cgccacacgc gggcagaagg
    22201 cccaggcgcc tcacgcctca cgcctcacgc ctcacgcctc attcctcacg cctcattccc
    22261 cacgccccca agactcgcct gcacgaagcg ccagatcagc gtggaggcgt ccgggcccct
    22321 ggggtcgctg aagtgttcgt cggcgacgcc gccgctccag gcgtggccga ggcgctcgac
    22381 ctcgcacagg cggacgcaca cccggcgctg cgcacgccag tcgctcaccg tcatcgggtg
    22441 acgtgccccg cgctgcaccc gccgcggcac ggcggcgcgc gcgccgagcg cggcggccca
    22501 ctgctcggcg gcggcgtggg cattgcgcac cgacaccacg cggtcgtcgc tgccgtggat
    22561 caccagcaga ggcggacggt tcccgcgctc gaccgcagtc tcgggcaggc tgcgcccgcg
    22621 catcgctgcc agcgccccgg cggccgagcg cgccgcgccc ggggcgacgc cggcgtgcat
    22681 cgccaccgca cagaagcgct ccggccagcg caccgcgagc agggccgcca tgctcgcgcc
    22741 cgcggacaac ccggccaccg cgaccgcgcc gcggtcgacc gggtagagca ggcaggcttg
    22801 atcgatcgcc gcgatcaggg tcgccgcctc ggcttcggcg cggtggctgc gcgtgtcgta
    22861 ccagttccag cagccctgcg ggttggcggc caggtcctgc tcggggtaga gcaccaggaa
    22921 gcgctcgcgc gaggcaagcc ggtccatgcg cgtgctgcgc gcgaaggccg ccgcgttctg
    22981 gccgcagccg tgcagcatca ccagcagcgg caggcgctcg ctgctgcgca cgccggccgg
    23041 gcgaaacagc cggaagcgcc gcagcccccc cggcccgatc gcctggccgg tgacccagtc
    23101 gccggtcgac gccggcaggc gatagggcgc ggacatcgcc tcgacaccac gcgccgcggc
    23161 cttgccggcg gcattcgcgc cggcacggat cgcgcgccgg gtcatggcgg tggtggcgcg
    23221 ctcgatggcg cgcaggaggg gcgaggggcg gacgcggcgg ctcatgcgcg aagggtcgca
    23281 cacccgcccg caaaaaagcg ccgatcctgt cggataaatt tacagtatcg acccatatac
    23341 ccactcatct atctgatttt attgaaaacc taaatcgggc acattttgtg ctttgaatgg
    23401 gcagcgacaa gtggaggcgg tgcgcctcac cgcgcctgtc gtattcccac gcacccgccg
    23461 tggacaccga aaaaggagat cgatcatgag aacaccctgt ccggaccagg cgggccgccg
    23521 gcttcgccac gcccgcaccc tgctgtgtgc cgccaccttg tgcgcgctgg ccaccgcacc
    23581 cgcacatgcg acgctgatca actaccagaa cttcgacaac ctctcggcgt tcaccctcaa
    23641 cggggcgacg gcgggcatca acaccggcgg ccagggtgtc gtcggtccca gtggagcgcg
    23701 cgtgctgcgc ctgaccaacg cgctctcgca agcaggcagc gccttcctga ccagcccgtt
    23761 ctcgctggcc gcggacgcct ccttcagcag ctacttcgag ttccagttca ccaaccagat
    23821 caacaacggc gccgacggca tcgtgttcac cgtgcagacg gtggccaaca ccgcgggcgg
    23881 ctcgggcggc ggcatcggct accagggcct gagccccagc gtcggcgtcg agttcgacaa
    23941 ctggaacaac ggcggcgggg acggcaacaa cgacaaccac gccggcatca acgtgaacgg
    24001 caatatggcc tcggtggtgc gcgctgacac tcttcccgcg cagctcgaca gcggctccgt
    24061 cttccactcc tgggtcgatt acaacggcgc gtcggacaag ctcgaggtcc gcctcgcgct
    24121 caccgacacc cgccccgccg ctgccctgat gagctacacg gtcgacctcg tgaccctgct
    24181 cggcaccacc aacgcgttca tcggcttcac ctccggcacc ggcgccgcgg gcgcctatca
    24241 cgacatccgg cgctgggtat ttaccggcga gttcaacccg atcgtcgacc ccgacgaccc
    24301 cgtggatccg ggcacagtcc ccgagcccgg ctcgctcgcg ctgctatcgc tcggcctgct
    24361 gggcgcgttc gccggcctgc gccgccgcgc cttggcaacc tgaacggtcc tgcgcctgca
    24421 ggcggcggcg agaagccgtc gcctgcagca ctcaaccgcc cccgccgcgc tcctcacgcg
    24481 ccaccgcggc cagttcgcgc aggtaccagg ccgcgtagcc gtagccggcc agcgcgacca
    24541 gcgcggagta gagcagctcg ccttcgagcg cgtggcccgc gagcatgttg gtgacgacga
    24601 cgaagctcag gtagagcgcg gcgaccatgc cgccgaagat gcggatgagg gcgaaggtct
    24661 tgcgctgctt gagggtgggc tgggccatgg ggagacgggg cgggacgagg agacaggcgg
    24721 cagggtagcc gattccggcc cggctggcat cgccggcggg cgcttggcgc ggacaatcac
    24781 aggaagctca tgtctgagcg cagcgcccag gccaagggat gctggcctcg ggtggcggcg
    24841 caccggataa tcggcccgct tccaccccct tccccgcgcg aggatctccg cgatgcatgc
    24901 tccggctccc ggccggcccg ggaccgcgcc cgcggcggcc tcccccgccc cggcgctgtc
    24961 gcccgccctg ctcttcctgc tcgtcttcgt cgagggcttc gtctcgctcg gcgccgagat
    25021 cctcgcgctg cgccggctgg tgccgcacgt gggcagcgcg atcacggtca ccgcgccgac
    25081 gatcgcgttc ttcctgctcg cgctggcgct cggctaccag gccggcgggc gcgtggcgga
    25141 cgactacctc gcgcgcgtgc ggcgcaactt cctgctcgcc gccgcgctga tcgcgctcgg
    25201 gctggcgggg ccggtggtgg agctggcctt cgcccatctg cagccggcgc cggtggcctg
    25261 ggcggtggtg gtgtgcggcg tgctgtgccc ggtggcctgg ctgctcggcc agaccgtgcc
    25321 catcctcacc aacctgctgc gccacgagcg catcggcgcg cgcagcgggg cggcgctgta
    25381 ctggtccacg ctgggatcct tcctgggcgc gctgacgctg tcgatggggg tgatgcagtg
    25441 gctgggggtg ggcgcggcgg tgctggtgtg caccggcctg ctgctcgcgg cggtgccggc
    25501 gctcggccgc gtcgccggcg cccgtatgcc atccgccgtg gcggcgctcg taatcgcgct
    25561 cgcggcgctg gcggtcaacc tcgtgctgcc gcagcagctc gagaccgcct acgccaccta
    25621 ccgcgtcgag gcggtggaga tccccggcta cgtggccccg gaggtcttcc gcatcaacaa
    25681 ctcgccggcc tccatcctcg acgccggcga gcagccacgc tacgcgcgct acatccgccg
    25741 cctgcgcggc ctgctgctgg acgagttggg ctttcgcggg cgcagcgtgc tggtgctggg
    25801 cgcgggcggc ttcacgctgt cgcaccgcga gccgctcaat cactacgtgt atgtcgacat
    25861 cgaccccgcc gtgaaggaga tcgccgagcg cgacttcctg cgcgagccgg tgcgcggcga
    25921 gttcgtcgcc gcggacgcgc gcgcccacct gcgcgccacc gccgcgcgtc acgacgcagt
    25981 ggtggtcgac gtctatagcg cgctcaccag catccccgcc catctggtca cgcgcgagtt
    26041 ctggcgcgcg acccgagccg cgctgaagcc gggcggcgtc ctcgccgcca acctcatcct
    26101 cgaccgcgag ctcgccagcc cctacgcgcg cagcctgctg gcgagcatcc aggccgagta
    26161 cggcgcgtgt gcggtcgagg tgctgtttcg cgaccgtccg cagggcaacg tgctggtgat
    26221 ctgcaccgcc ccgtccgcgg cgccggcgga gcccgcccac ccctacaccg acgagcgcaa
    26281 ccgcgccgac ctcgacgtgc tgcgcggcgg ctgatcaacc ctccgccagc gcggcctcga
    26341 agagctcgag cggcagcggg cggccgaaca ggtagccctg gtagtcgcgg cagccctggg
    26401 cggcgaggaa gtcgtactgc tcctcggtct cgaccccctc ggcgatcacg gcgaggccga
    26461 ggttgctgcc gagggcgagg atggtgcgcg cgatggtggc gtcgttgggg tccgacatga
    26521 cgtcgcgcac gaaggactgg tcgatcttga gctgcgcgag cggcaggcgc ttgaggtagg
    26581 cgagcgagga gtagccggtg ccgaagtcgt cgagcgagaa gcggatgccg agcgctcgca
    26641 aggcctccat gcgctcgatc acgccctccg catcctcgat caggctgctc tcggtgagtt
    26701 cgagcttgag ctgctcggcg ggcgcccccg tctgcgcgag cagcgcgcgc acctcgtcgg
    26761 cgaagcgggg ctggcgaaac tggcgagcgc tgacattcac cgcgagctgc aggtgggcgg
    26821 tctgcgtctg caacgaccag cgcgcaagct gacggcacgc ggtctccagc acccagtggc
    26881 cgatcggcac gatcaggccg gtctcctcgg cgagctcgat gaagccgccc ggggcgagca
    26941 gtcccttgtg cggatgccgc cagcgcagca gcgcctcagc gcccgagggc cgccgccggg
    27001 agtccacctg gacctggtag tgcagctcga actgtccgcg acggatggcc tcgcgcaggt
    27061 cggcgtgcag gatcgcgcgc tcggtgaccg ccgcctgcat cgccggatcg aagaagcaga
    27121 tcgcatttcg cccggccgcc ttggcctggt acatcgcggt gtcggcgcgc cgcaacagct
    27181 cggcggcacc gagctcggca cgaccgaagg caccgacgcc gatgctcgcc gaaacctgat
    27241 gggtgatgcg ctcgtcgtcc ttgccacagc gcaggtggaa gggacgtgcg agctcctcgc
    27301 agatgcggga ggcgatcgcg ctcgcctgcg caatcccgtc gagatcctcc aggatcacca
    27361 cgaactcgtc cccgcccagc cgggcggcgg tgtcgccctg gcggatgcag gcgttcaggc
    27421 gcacacccgc ctcgaccagc agctggtcgc cggcgtcgtg gccgtgggag tcgttgaggt
    27481 ccttgaagtg atcgaggtcg atcagcagca gcacgccctc ggtgccacgg cgcgcgctcg
    27541 cgcgcagcgc gtggtcgagg cggtcgtaca tcaggcgccg gttgggcagg ccggtgagcg
    27601 gatcgaagaa ggccagctcg tggatctggc gttcctggcg cttgcgttcg gtgacgtcct
    27661 ggttgaagcc gaagatcccc acgacctcgc cgtccacccg gatcggcgcc accaggcact
    27721 ggtaggtccg gcgctcgccg tcgatctcgt actcgacctc cttgtgcacg gtctcgcccg
    27781 cgtaggcgcg gcggttgctt tccccccagt cggcactcac cggctccgtc tcgcccgagt
    27841 cctcgacgcg cttgccgagc aggtcgcccc agtgcgccgc ggtcatcgcg ttctgcatga
    27901 tgcagcgccc ctgcagatcg cgcgcccagt actcgaccgg ggtgttgtcg accaccgcac
    27961 gcagcagcga ctcgcgctcc tgcagcgcct gctccatctt cttgcgtacg gtgatctcgc
    28021 gcgaaagcac gttgaagcgc tgcggctcgt ccccactgcg cgccatcggc gccaccgaca
    28081 gctcgaacca gcgcatgccg cccggggtgt cgaccttgaa caccttgccg ctggaatgtc
    28141 cgcgcgctgc cgcctctcgc aaggcctcga gacaggtctc cgcctccgcg gggggcagca
    28201 cctcgcgcac cgtgcgcccc atgaacaaag agggcggcgc cgccagaagt gcctcgctcg
    28261 gcgtccggta ggacaggcag cgtccttcgg catcgagcac gaacagcggg tcgggcaggg
    28321 cctgcaggat cgccgcgtag tcgttcttga gcgcgaccag ctcgcgctcg gcacgcttgc
    28381 gcgcggtgat gtcgatggtc aggccagcca cgccgtccgg ccggccgtct tcttcgaaca
    28441 gcggctgctt gatgctgagt ccccaggtca tctccggatg gccggggagc ctgagtcttt
    28501 cctccgcgat caccggctcg cgcccggcca tcgcgcgccg gtcgtgcgcc tgcatcgcgt
    28561 cggcgagatc gggcggaaaa agctcggaat cggagcgtcc gaggacgtcc gtgcgcgaac
    28621 actcgagcag ctcgcaggca aggtcgttgg cgtagccgta acgcccttgc ggatccttga
    28681 tgtagatggg cacgcgcaac ttgtcgatcg ccgccctcag acgtgcgtta tcgtccttca
    28741 tctgcaaccg ctctcctcgg ccatggaagt cgggatcgtt cgggcgcccc gggtcggact
    28801 attttgacag tctccgggcc gcacgggctg cctccgactc cgaaatgcat acgtcaccac
    28861 accgcctcgc aagatgacca tcctccgcct gatcctcggc gaccagttga acgccgccca
    28921 cacctggttc cgtgccccgc gcaccgacgt gcagtacgtg ttgatggagg tacgcagcga
    28981 gaccgactac gtgcgccacc atgcgcagaa ggtgctggcg atcttcgccg ccatgcgcac
    29041 gttcgccgcc gcgctggaag cggccggaca tcgcgtgcgc tacctgaaga tcggcgacac
    29101 cggcaaccgc cagtccttcg ccggcaacct cgcgctggtg gcggccgagt gcggcgcgac
    29161 gcgcttcgag cgcatggagg ccgacgaatg gcgggtggag cgggtgctgg acgaagccgc
    29221 gcagaagctc ggcctgccgc atgcggtggt ggacagcgag cacttcctcg ccgatcgcgc
    29281 cgagctggca cggcgcttcg ccgccaaggt gccgcgcatg gagttcttct accgcgacat
    29341 gcgccgccgc caccgcatcc tggtcgacac ggacgacgcg ccggtgggcg gggtgtggaa
    29401 cttcgacgcg cagaaccgcg agaaatggcc gggcgatccg cccgcaccgg cgtggccgtg
    29461 gggcggccac gacctgagcg ggctgtggga cgagatcgtc gccgcgggcg tggagaccat
    29521 tggttcagct catgcggaaa acctgctctg gccgctgagc cggcgcgagg cgcgcgccgg
    29581 cctggcgcac ttcatcgccc acgccctgcc ctggttcggt ccctaccagg acgcgatgag
    29641 cacgcgctcg accacgctgt tccactccgg gctgtcgttc gcgctcaacg tcaagctgct
    29701 gcacccacgc gaggtcatcg acgccgcggt cacggcctgg caggcgggca cggtcgagct
    29761 cgccagctgc gagggtttcg tgcgtcagat cctgggctgg agggagttcg tgcgcggggt
    29821 gtattgggcg cgcatgccgg gctacgcgca gggcaacgcg ctcgacgccc ggcgcccgct
    29881 gccggcctgg tactggaccg gcaggacgaa gatggcctgc ctgcgccacg ccattggcca
    29941 gtcgctcgac accgcctacg cccaccacat ccagcgcctg atgatcaccg gcaacttcgc
    30001 gctgctggcg ggctgcgacc cggacgaggt ggacgcctgg tacctgggca tctacgccga
    30061 cgccttcgag tgggtggaga tgcccaacac ccgcggcatg agccagttcg ccgacggcgg
    30121 cgtgatcgcc agcaagccct acgccggcgc ggcgagctac atcggcaagc agtcggacta
    30181 ctgcaaggcc tgcgcctacg acgccaagcg ccgccatggc ggcagcggca agcccgcctg
    30241 ccccttcaac agcctgtact gggattacct gctgcgccac gaggcccgct tcgcgcgcaa
    30301 cccgcgcatg gccatgccct acaaggcgtg ggcgaagatg gacgcgaccg agcgcgccgc
    30361 cacgctggcg caggcggcgg actaccttgg caagctggac gagttgtaag ggtgcggtgc
    30421 gcgaggcgcg cgcatcgcct gcccggcagc cgtgttcgcg gctgccgccg ctcctacagg
    30481 gccccgtcgg cttcgcgact tgcctcgcct ctgcaggagc gtgtcggttc atgtaggcgc
    30541 gccggcaggc gcgaaggcgg ccgtgccgac ggtcgcatgc gtcgcttgcc agaccgcgcg
    30601 cttcgcggct tgcgtcgccc ctacaggagc gtgtcggtcc atgtaggagc gccggcaggc
    30661 gcgaacacag cggctcagcc cgcgagcgca cgcacgtcgg cgagcagcgc gtccacgctc
    30721 gccggcagcg tgtcccagcc gcacatgaag cgcgccccgc cggcaccgat gaaggtgtag
    30781 aagcgccagc cgcgcgcgcg caggccgtcg agcaccgcgg gcgggagctc gcagaacacg
    30841 ccgttggact cgaccgggaa catcagccgc gcacccggca cctgcatcag cccgctggcc
    30901 aggcgctgcg ccatggcgtt ggcgtggcgg gcgtgcttca gccacacctc gtcttccagg
    30961 atgccgagcc agggcgcgga caggaagcgc atcttcgacg ccagctgccc ggactgcttg
    31021 cagcgatagg cgaaatcctc cgacagcctg cggtcgaaga acaccaccgc ctcgcccacc
    31081 ggcaggccca tcttggtgcc gccgaagcac agcacatcca cgcccacctt ccaggtgatc
    31141 tccgccggcg ccacgccgag cgaggccacg gcgttggcga agcgcgcgcc gtccatgtgc
    31201 acgcgcaggc cgtgctcgcg cgcgcaggcg gcgatcgccg ccacctcttc gggccggtac
    31261 accgtgccga cctcggtgct ctgcgtcagc gtgaccacgc gcggcttggg gtagtggatg
    31321 tcgctgcggc gcgagatcac ctccagcacc gcggcgggcg tgagcttgcc gtatgcgccg
    31381 tgcgcgggca gcagcttgga gccgttggag aagaactccg gcccgccgca ctcgtcggtc
    31441 tcgacgtggg ccagctcgtg gcacacgacg ctgtggtagc tctggcacag cgaggcgagc
    31501 gcgagcgagt tggcggcggt gccgttgaag acgaagtaga cgtcgcagtc ggtctcgaac
    31561 agctcgcgca ggcggtcgga gaccttgcgc gtccattcgt cctcgccgta ggcgggtgcg
    31621 tggccggcgt tggccgccac gaaggccgcg agggcctccg ggcagacgcc ggcgtagttg
    31681 tcgctggcga agtgctggat cggctgcatg cggggatcag gcacggtcca ggttcaacgg
    31741 ctcaccgctc tcggcagcgc aggccgcggc ggtgaagagc acgtcggtcg aggagttgag
    31801 cgcggtctcg gccgagtcct gcaccacgct gatcacgaag ccgatcgcca ccacctgcat
    31861 cgccacgtcc gcggagatgc cgaacagggc ggtcgccatc ggaatcagca gcagcgagcc
    31921 accggccacg cccgacacgc cggcagcggc gagcgaggac acgatgcaca gcagcagcgc
    31981 ggtggcgaag tcgaccggta tgttgagggt gtgggcggcg gccagcgtca tcaccgagat
    32041 ggtgatcgcc gcgcccgcca tgttgatcgt ggcgccgagc gggatggaga tcgagtaggt
    32101 gtcctcgtgc aggcccaggc gacggcacag ctcgaggttg atcgggatgt tggcggccga
    32161 gctgcgggtg aagaaggcgg tgacgccgct ctcgcgcaga caggtgaaca ccagcggata
    32221 ggggttggtg cgcagcttcc agaacacgaa cagcggattg accaccagcg cgacgaagac
    32281 catgcagccc acgatcatca gcagcagctt gccgtaaccg agcagggcgt cgaggccggc
    32341 ctcgcccatg gtggcggcga ccaggccgaa gatgccgagc ggcgcgaagc ggatcaccac
    32401 atggacgatc tgcgagatcg cgtcggcgag gtcgttgagg accttgcgcg tgccttcgcc
    32461 ggcgtggcgc agggcgatgc ccaggccgat cgcccacgcc aggatgccga tgaagttggc
    32521 ttccatcagc gcgcgcaccg ggttcgagac cgcgctcagc agcaggttct tgagcacgat
    32581 caggatgccg cccggcgggt tgccggcggc agccggcgcg tcgagcacca gcgtggtcgg
    32641 gaaggcgaag ctggcaagca ccgcgaccag cgcggcggcg aaggtgccga gcaggtagag
    32701 catcagcacc ggacggatgt gggtgggctg gccctgcttg tggttggcga tcgccgccgc
    32761 caccagcacg aagaccagga tgggcgcgac cgccttcagc gcggcgatga agaggtcgcc
    32821 gagcagggca accgatttgg tggcgcccgg cgcgatcagc gccagggcga cgccgaggac
    32881 cagaccgatg gcgatctggg agatgaggct catgcgcagc aagcgctgca gggccgtggg
    32941 ggttgcggta gtcattgagt gtctcctcgt ggatgacctt gtggttaggg atgccgggtg
    33001 aggcgtcgcc cttgcgcggc gggggtgcac cgcgcaaggg ccggggtgaa gcggatgcgg
    33061 agcttcggag agccggattg ccgagggttc gtgtggcgtc gcgctcagca ctcggggaag
    33121 ctgacggcga ggccgccgcg cgaggtctcc ttgtacttgt cgagcatgtc gcggccggtg
    33181 tcgcgcatgg tgcggatcac ctggtcgagc gagaccgtgt gcgcgccgtc gccgcgcagg
    33241 gcgagctggg cggcgttgat cgccttgatc gaggccatcg cgttgcgctc gatgcagggc
    33301 acctgcacca ggccgccgac cgggtcgcag gtgaggccga ggttgtgctc gaggccgatc
    33361 tcggcggcgt tctcgacctg ctcggg
//
LOCUS       DAOTIN010000029        33006 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_1488_length_33006_cov_9.640830, whole genome shotgun sequence.
ACCESSION   DAOTIN010000029 DAOTIN010000000
VERSION     DAOTIN010000029.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 33006)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 33006)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33006
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1488_length_33006_cov_9.640830"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(148..3414)
                     /locus_tag="P5537_06505"
     CDS             complement(148..3414)
                     /locus_tag="P5537_06505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002944786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016866 - intramolecular transferase
                     activity [Evidence IEA];
                     GO_function: GO:0031419 - cobalamin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl-CoA mutase family protein"
                     /protein_id="HRV77732.1"
                     /translation="MTDLSVAHKLSPYKPKNKVRFVTAAALFDGHDASINIMRRILQS
                     TGSEVIHLGHNRSVGEIVNAALQEDVQGIAITSYQGGHVEFFKYMIDLLKANGGEDIK
                     VFGGGGGVIVPAEIKELHEYGVTHIFSPEDGAKMGLQGMINSVVERCDVDVTKAAPPK
                     ADAVLKALAAGDRRALAQIITALENGGYGDEVKKALIDAAAKTKVPTLGITGTGGAGK
                     SSLTDELVRRFRLDQDDKLKLAIVSIDPSRKRTGGALLGDRIRMNAIEHANIYMRSLA
                     TRDTGSEVSAALPEVIAACKLAGFDLVIVETSGIGQGNAAIVPFVDLSLYVMTPEFGA
                     ASQLEKIDMLDFADFVAINKFDRKGALDALRDVAKQYQRNRELFGQRPEEMPVFGTMA
                     ARFNDDGVTALYQAVLPALVGKGLKVAKSKLPVVKVRSSSEGRAIVPADRTRYLAEIA
                     DTVRGYHKHIEQQARVARERQSLKIAKGLFEQCGKDAGSFAEMIDWKDGELTPAARKL
                     LDMWPKTRELYAADEYVVKIRDKEIRTQLTSTSLSGSKIRKVALPNFEDAGETLKFLM
                     KENVPGSFPYTAGVFAFKREGEDPTRMFAGEGDAFRTNRRFKKVSEGMPAHRLSTAFD
                     SVTLYGCDPDLRPDIYGKIGNSGVSIATLDDMKVLYDGFDLCCPTTSVSMTINGPAPI
                     ILAFFFNTALDQQVVKFKADNGREPTEDELQKIKEWTLSTVRGTVQADILKEDQGQNT
                     CIFSTEFALKMMGDIQEYFVHHDVKNFYSVSISGYHIAEAGANPISQLAFTLSNGFTY
                     VESYLARGMHIDDFAPNLSFFFSNGMDPEYSVIGRVARRIWAVAMKNKYGANERSQKL
                     KYHVQTSGRSLHAQEMDFNDIRTTLQALIAIYDNCNSLHTNAYDEAITTPTEESVRRA
                     MAIQLIINREWGLAKNENPNQGAFIIEELTDLVEEAVLKEFEAIASRGGVLGAMETGY
                     QRGKIQEESLYYEHKKHDGSYPIIGVNTFLNPKGQAQQEIELARSTEEEKQGQLKRLA
                     DFHARNKAEAPKWQAKLQQAVIDNTNVFEVLVDAVRYCSLGQITEALYKVGGQYRRSM
                     "
     gene            3919..4905
                     /locus_tag="P5537_06510"
     CDS             3919..4905
                     /locus_tag="P5537_06510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HRV77733.1"
                     /translation="MLAGLERRGLDPAPLLARAGIDLAETDTRIPVERYALLYNLCVE
                     ALDDEAFGLLPEPMRPGSFEFLCRALLGAPTLGEALRRAIRFLRIVLPAFRIELRVAG
                     ARAELLIDDDGSLGPARDAPARVFAYEWLLRLLHGVASWFVARGLALDAVAFPYARPA
                     HAEDYALVYTEHSSFDAQRLSARLQANLLELPLRRDEAALVGFLDGAPGKITTLYRRD
                     REMVFRVRDILRDALPQNLSLEEVAERLHVSPRTLHRRLEEEGSGFRNIKEATRRDIA
                     YARLAKTRQPIAGIAAELGYADPSTFYRAFVAWSGVSPERFRDQATGRKPPP"
     gene            5478..7637
                     /locus_tag="P5537_06515"
     CDS             5478..7637
                     /locus_tag="P5537_06515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS-domain containing protein"
                     /protein_id="HRV77734.1"
                     /translation="MKNDDGNIPYSALSPEQRRRYDLLLAGLDLLDQAIAVFDATPKL
                     VTWNKAMLRLLDFPESMVRVGTPFEEFARFNAERGEYGPGDIDTLVRARVAAARSFQP
                     HYVERARPNGRILAVRGVPIPNLGFVSLWTDITEQRRAAQLIEEQNAQLENRVRERTA
                     ELEAANARLAQANLEIDDIAGALRRSENRLQLIIDSIPALIAYVGSDDIYRFANKGYA
                     EWFGFAKDAIIGRSIGEVFGAEAFAQIQPHLERARAGERVSYEYSRTLADGRMVHARS
                     VVVPELDGDGRTVGFFVMSIDITEQKASQAALVQAQKMEAVGQLTGGLAHDFNNLLTI
                     IIGNLSALQQRIGAGPGAEFVDPSLQAARRGAELIRRLLTFSRRQPLAPTAVEVGVLV
                     HNMTHLLARTLGETIRIHLRLPGEPVHALVDPHQLENAILNLAINARDAMPEGGELTI
                     GVSRRELDDALAAVVEVPPGEYVQIDVGDTGKGIEPAVLQRVFEPFFTTKDFGSGSGL
                     GLSMVYGFVRQSGGNIRIRSTPGRGTHVRFVLPTATAAVLAPERVATATAGTRALDGP
                     VLLVEDEPEVRKVVRMQLTGLGHAVIEAADGVEALGLLQHVDDIALLVSDTVMPGGIG
                     GRELARRARALRPQLPILLVTGYASEATPTDELPADVPTLRKPFDQATLAAALATLLG
                     PEPGAAGGVEAASPTAPAADGQPQSPITNTTTEPRPQ"
     gene            7634..8362
                     /locus_tag="P5537_06520"
     CDS             7634..8362
                     /locus_tag="P5537_06520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HRV77735.1"
                     /translation="MTQSPTDPSQARIFVLEDDPEVARLICMSLGEYGFRCEQMRAGR
                     QLLERARQVAPDLCIVDLGLPDMDGMQVVRELQDGSPCAVLILTGRNDVTDRVLGLEL
                     GADDYIVKPFEPRELVARVRSILRRYQRAASAEPAGERNTARFAGWTFDANRHALVAP
                     DGREVSLSAAEAGLLATLLRRPNKILSREQLLGERDVDPFDRSIDVRISRLRRKLDDD
                     PQNPRLIKTVYGAGYLFSVQVEWA"
     gene            complement(8699..9454)
                     /gene="rlmB"
                     /locus_tag="P5537_06525"
     CDS             complement(8699..9454)
                     /gene="rlmB"
                     /locus_tag="P5537_06525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HRV77736.1"
                     /translation="MAKAPENTPTRLIYGFHAVSAKLRHVPDAVLEIFLTADRKDARV
                     RKFLAQAETAGVRITQSEGDKLDALVGTRRHQGVVAKVDATRREIKLADVLDSLDENA
                     LILVLDGVQDPHNLGACLRVADAAGAHAVVAPKDRAVGLNATAVKVASGAADTVPYIT
                     VTNLARALREMQDAGVWVVGAAGEAEKTLYEVDQKVPVAWVLGAEGDGLRRLTRETCD
                     ELARIPMHGSVESLNVSVASGICLFESRRQRSA"
     gene            complement(9447..12515)
                     /gene="rnr"
                     /locus_tag="P5537_06530"
     CDS             complement(9447..12515)
                     /gene="rnr"
                     /locus_tag="P5537_06530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008997 - ribonuclease R activity
                     [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HRV77737.1"
                     /translation="MTRKTKKTDQPRSGASSRKTQAAAQQDAPRATSAGRKAGRGASS
                     APAAPDARSTVASSQSAAHHAGSPVRGAGRSRAARKAGAAQASAVRLADPFYERETQQ
                     YDNPLPSREYVLQLLAERGVPMPFSELAAALDIAPHELDFFDRRLRAMERDGQVVRNR
                     RDAYLLPAKADLIKGRVEGHPDGFGFLRRDDGEPDVFLGPKEMREVLHGDRVMVRISG
                     TDRRGRPEGKLVEVLERANTRVVGRIINEHGVMIVVPENRRLAQDILVAPGGRKKPEP
                     GQIVTVELVEQPTKFAQPIGRIVEVLGNYADPGMEIEIALRKHDLPFEFSPEAKAQTR
                     KLPEAVRKKDWAGREDLTKLPLVTIDGETAKDFDDAVYCERQGKGYRLIVAIADVSHY
                     VDAASALDKDAFDRGNSVYFPRRVIPMLPEKLSNGLCSLNPQVERLSMVADMAISATG
                     EIKNYRFYPAVIWSHARLTYTKVAAALYENDAATRAELAPLLPHLENLDKLFRVLLKA
                     RAKRGAIDFETTETRMIFDDNGKIAQIVPEVRNDAHRLIEECMLAANVCASDFLASRE
                     HPALYRIHDSPSEDKLAKLREFLKEFGLGLGGGDEPRASDFAKLLEQVKDRPDAQLLQ
                     TVMLRSLKQAMYSPDNVGHFGLAYESYTHFTSPIRRYPDLLIHRGIKAALGGEQYRPG
                     DWEQIGLHCSMTERRADDATRDVVAFLKCYFMQDRVGEEFTGSVSAVVPFGLFVALDD
                     IFIEGLLHISDLGSDYFHYDETRHALMGERTGKQFRLSDRVKVQLVRVDMATNKIDFR
                     LIEGPLPVEAKTPAKVAEAAAVEAVPAEGRKARKPRSRKGGVEERGVALPVPVVEAVP
                     AAPEPAAPKSRSKRAKKAAAEVVVEPAAAPVVEAAPAAPEPAAPKSRSKRAKKAAAGA
                     VVEPVAAPVVEPAPAAPEPTAPKSRARRAKKAAAEAAVEPVATPVVEAAPAAPEPAAP
                     ESRAKRVKKATASPAVETPAAPAAEALESAPPAPARRAGRKTTTKGSDRG"
     gene            12555..12639
                     /locus_tag="P5537_06535"
     tRNA            12555..12639
                     /locus_tag="P5537_06535"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12589..12591,aa:Leu,seq:cag)
     gene            13032..13116
                     /locus_tag="P5537_06540"
     tRNA            13032..13116
                     /locus_tag="P5537_06540"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13066..13068,aa:Leu,seq:cag)
     gene            complement(13317..14627)
                     /locus_tag="P5537_06545"
     CDS             complement(13317..14627)
                     /locus_tag="P5537_06545"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015434464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HRV77738.1"
                     /translation="MAKNVVVVGTQWGDEGKGKIVDWLTDHAKGVVRFQGGHNAGHTL
                     VVGKTEYKLNLVPSGIVREGVACFIGNGVVLDAHHLLSEIRTLEAGGIKVRDRLRVSP
                     GCPLILGYHAALDRAREAAKSAGDKIGTTGKGIGPTYEDKVARRALRVYDLFDRERFA
                     AKLKANLEYHNFVLTQHLGAEPVDFQSVFDQAMADADELLPMVADVSAELYAINKSGG
                     SLLFEGAQGTLLDIDHGTYPFVTSSNCVAGQAAAGSGVGPGRLHYVLGITKAYCTRVG
                     GGPFPTELDIETKGVPGEQMSTKGREFGTVTGRKRRCGWLDLAALKRSIIINGVTGLC
                     ITKLDVLDGLEELKLCTGYMLDGKRIDLLPMGSEEVMRCEPIYETMKGWSGTTFGAQS
                     WDALPQEARTYLHRIEEICEIPIDVISTGPERDETILRRHPFGA"
     gene            complement(14632..15789)
                     /locus_tag="P5537_06550"
     CDS             complement(14632..15789)
                     /locus_tag="P5537_06550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HRV77739.1"
                     /translation="MRWVLPDHIQDALPSDAHRLESLRRRLLDAFRLRGYQLVMPPLL
                     EYLDSLTTGAGKDLELRTFKLVDQLSGRSMGVRADMTPQVTRIDAHLLNRRGVSRLCY
                     CGSVLHTLPSTLTGTREPLQLGAELYGHAGIEADVEILRLLAEVLRLAEVPASRIDIG
                     HVGLFHALAARAGLVPGREEELFGLLQAKDVPELRRVLADVPEPARSALLALPELYGG
                     PEVLAEAAARLPQDAEIAGPLAELRQLAEALGDLPVSFDLADLRGYHYHSGVVFAAYG
                     AESPAALALGGRYDRVGQAFGRARPATGFSLDLRELAWHLPAPAAPAGAVLAPSDDDA
                     ALAAEVSALRARGEIVMVALPGHEGTWNEAGCDRQLVKRGDRWAIVPLQGE"
     gene            complement(15797..15982)
                     /locus_tag="P5537_06555"
     CDS             complement(15797..15982)
                     /locus_tag="P5537_06555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2065 domain-containing protein"
                     /protein_id="HRV77740.1"
                     /translation="MASSLLTAFALMLIIEGLLPFIAPAAWRDTFLRLASMADGQIRF
                     IGLSSMLAGLAMLFIVL"
     gene            complement(15990..16871)
                     /gene="hflC"
                     /locus_tag="P5537_06560"
     CDS             complement(15990..16871)
                     /gene="hflC"
                     /locus_tag="P5537_06560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0045861 - negative regulation of
                     proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protease modulator HflC"
                     /protein_id="HRV77741.1"
                     /translation="MRDKMSLIGGTLLLLVVIASMSLFTVDQRQYAIVFQLGEVKEVI
                     SEPGLNAKLPFIQNVRYFDKRILTMDTPEPERFITSEKKNVLVDHFVKWRIVDPRLYY
                     ESVAGDEARARTRLTQTVNAGLREEFGRRTVHDVVSGERDNIMEQMRERADRDARTIG
                     VQIVDVRLKRVDLPNEVSESVYRRMEAERKRVANELRSLGAAEAERIRADADRQREVI
                     IAEAYRSAQEVKGEGDAKATAIYADAFGKDREFYSFYRSLEAYRASFAGKDDVLVVDP
                     SSDFFRFMKDAGGAPRN"
     gene            complement(16871..18178)
                     /gene="hflK"
                     /locus_tag="P5537_06565"
     CDS             complement(16871..18178)
                     /gene="hflK"
                     /locus_tag="P5537_06565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002944221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0045861 - negative regulation of
                     proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsH protease activity modulator HflK"
                     /protein_id="HRV77742.1"
                     /translation="MSLNDPRWGGQGGGDREDGNRGDDNRNDDLRGDRNRGGNQGPPD
                     LEEVWRDFNQRLSGMFGGKRSGRGSGFGGGNGGGGGNRPELPGFSFKQFRGGFGVLAA
                     LVLVVWLASGLYTVDANQRAVVLRLGEYVATTEPGLRWRLPAPFETHEIVDLTGVRTV
                     EVGYRGSERNKVLRESLMLTDDENIINIQFAVQYVLNSPENYVFNNRFPDEAVAQAAE
                     TAMREIVGKSRMDFVLYEGREEIATTAHELMQRILDRYETGIQVSRVTMQNAQPPEQV
                     QAAFDDAVKAGQDRERQKNEGEAYANDVVPRARGTASRLVEEANAYRERVVANAEGEA
                     SRFNQVFTEYSRAPEVTRERLYLDTMQQVMSSTSKVMVDARGNGNLLMLPLDKLMQQT
                     GAKPAAAPPPDSQSAAGLAANAPVPAFDPRNREGMFSRERGVR"
     gene            complement(18193..19350)
                     /gene="hflX"
                     /locus_tag="P5537_06570"
     CDS             complement(18193..19350)
                     /gene="hflX"
                     /locus_tag="P5537_06570"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HRV77743.1"
                     /translation="MFERPATGERAVLVQLDLGQGAIDERLSELKLLVLSAGASVEAV
                     VQGRRAAPDPKLFAGSGKVQEIGEALRAYGGDIVIFNHALSPAQQRNLERELQCMVID
                     RTALILDIFAQRARSHEGKLQVELAQLEHLATRLVRGWTHLERQKGGIGLRGPGEKQL
                     ETDRRLLGNRVKMLKSRLAQIEKQRKVRRRARERRDVLSVSLVGYTNAGKSTLFNALT
                     KAGAYAADQLFATLDTTSRRLYVGGEGAGASVVLSDTVGFIRDLPHALVAAFQATLEE
                     TAQADLLLHVVDSASEDRDAQIEAVNQVLAEIGAADVPQILVWNKIDLTRAAAAVERG
                     DCGTIRRIFLSARTGEGLELLRDALAEVARQTFGDNADRPAGSDDERRQET"
     gene            complement(19405..19641)
                     /gene="hfq"
                     /locus_tag="P5537_06575"
     CDS             complement(19405..19641)
                     /gene="hfq"
                     /locus_tag="P5537_06575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HRV77744.1"
                     /translation="MSNKGQLLQDPFLNTLRREHIPVSIYLVNGIKLQGQIESFDQYV
                     VLLKNTVTQMVYKHAISTVVPARPVVIQQEEGAN"
     gene            complement(19757..21085)
                     /gene="der"
                     /locus_tag="P5537_06580"
     CDS             complement(19757..21085)
                     /gene="der"
                     /locus_tag="P5537_06580"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HRV77745.1"
                     /translation="MKPTIVLVGRPNVGKSTLFNRLTRTRDALVADQPGLTRDRHYGI
                     GRVGDRDYLVVDTAGFDPVAKDGIMHEMARQAEQAIAEADVLLFLVDGRAGRTPHDEN
                     IAARLRRAGRPVHLVVNKAEGIDRAMVAADFHALGLGDPLPVSAAHGDGVKQLVELVL
                     APFPADDEKEHSDDEGPKVAIVGRPNVGKSTLVNTLLGEERVIAFDMPGTTRDAISIP
                     FERGGKRYTLIDTAGLRRRGKVFEAVEKFSVIKTLQAVQECNVVVLVLDAAQDISDQD
                     AHIAGFALEAGRALVVAINKWDAVDDYRRDRLKADIARKLAFLSFARFHQISALKAEG
                     IAGLLKSVDAAYAAATANLATPRLTRALQQAVARQAPPRHGLARPKMRYAHQGGMNPP
                     VIVIHGNALDDIPQSYVRYLERCFIDAFDLKGTPLRIQFRTTHNPYATRN"
     gene            complement(21099..22241)
                     /gene="bamB"
                     /locus_tag="P5537_06585"
     CDS             complement(21099..22241)
                     /gene="bamB"
                     /locus_tag="P5537_06585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamB"
                     /protein_id="HRV77746.1"
                     /translation="MKTPTPRLVPLLAAALLAAGCSSLNPFASSGPKPAALVDFKPAA
                     QLVAKWQANIGEAEHYRFQPAVWSDSVFAAGNEGEVARFEDGRELWRIDTGSELSAGV
                     GTDGRLAVVVATDGTVIALDTDNGSERWRAPIGAEVLAPPAVSLELVIVRASDNRLIA
                     LNARDGSRRWVYQRNNPPLALRSFAGVVLEGPVVLAGFPGGKLAVINAANGGAITELN
                     VAVPRGATELERVADVAGMPVVGRREVCAVAYQGRAACFDTSNGNAIWARDFSSSVGM
                     DRDARYALITDDRDAVHALDAYSGASVWKQDALARRQVSRPLIVGDYVVVGDLEGYVH
                     ALSRETGAFAARERAGSDPIVADPVPLRRGFVVQGAGGDITAYEVR"
     gene            complement(22245..22889)
                     /locus_tag="P5537_06590"
     CDS             complement(22245..22889)
                     /locus_tag="P5537_06590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HRV77747.1"
                     /translation="MAVYDLEEQEQISELKAWWAQYGNFVVTLAVVAALASVGWQAWN
                     WYQNRNAGEAGALYYAVQQAVEKNEPQKAREAAGRLVGEHGGSVSAQLGALLSAAMQF
                     EAGDLVNARAQLEWAAEKGSDPALRELARLRLAAVLLQQGELDAALARLQAAPSAAYK
                     ARFDDLRGDVLAAQGKAAEARAAYQAAIDALTAAGDDAVTLREVVRVKLESLGA"
     gene            complement(22892..24187)
                     /gene="hisS"
                     /locus_tag="P5537_06595"
     CDS             complement(22892..24187)
                     /gene="hisS"
                     /locus_tag="P5537_06595"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HRV77748.1"
                     /translation="MSQTLQAVRGMNDILPTDAETWEYFEDIVRDWLQSYGYRPIRMP
                     LVEPTPLFKRAIGEVTDIVEKEMYSFEDALNGEHLTLRPEGTASCVRAAIQHNLIPSG
                     GPQRLYYYGPMFRHERPQKGRYRQFHQIGVEALGFAGPDADAELILMCARLWDDLGLE
                     DVALEINSLGSLEERAQHRAALIAYLEQHQDKLDEDGKRRLYTNPLRILDTKNPELQA
                     IVEAAPRLADYLGDESKAHFDAVQVFLKDAGIPYRINHRLVRGLDYYNRTVFEWVTTR
                     LGAQGTICAGGRYDGLFEQLGGKPQPAAGFAIGIERLLLLWLACGGEAERPVPDVYVV
                     SVGEAAQRLGFRAAETLREHGFAVLMHCGGGSFKSQMKKADASEAPVAIVIGEDEAAA
                     GEVGLKPLRGSGAQQRVPIDELVEAMAALMFPEEDEEEV"
     gene            complement(24245..25504)
                     /gene="ispG"
                     /locus_tag="P5537_06600"
                     /gene_synonym="gcpE"
     CDS             complement(24245..25504)
                     /gene="ispG"
                     /locus_tag="P5537_06600"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004327074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity [Evidence IEA];
                     GO_process: GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HRV77749.1"
                     /translation="MNLHPELQPIEASPLARHRTHQVRVGKVRIGGEAPVVVQSMTNT
                     DTADVLATAMQVAELARAGSEIVRITVNNEAAAAAVPKIRDRLLALNMDVPLVGDFHY
                     NGHKLLTDFPACAEALAKLRINPGNVGAGRKRDPQFAAIVELACRYDKPVRIGVNWGS
                     LDQSVLARIMDENAKRAEPRDAGAVMREALVVSALESAAKAEEYGLGRDRIILSAKVS
                     SVQDLIAVYRDLARRSDYALHLGLTEAGMGSKGIVGSTAALAVLLQEGIGDTIRISLT
                     PEPGGSRTQEVVVAQEILQTMGLRAFTPMVTACPGCGRTTSTFFQELASSIQDYVRAQ
                     MPVWREQYDGVENMTLAVMGCVVNGPGESKHANIGISLPGTGETPAAPVFVDGEKVVT
                     LRGDNIAAEFKAIVDNYIATRYVKKGA"
     gene            complement(25515..26552)
                     /locus_tag="P5537_06605"
     CDS             complement(25515..26552)
                     /locus_tag="P5537_06605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HRV77750.1"
                     /translation="MQSDHLAPGAESAISPGVRLRRAREARGESVHEAAFAIKLSPRQ
                     IEALENDDFAALPGMAFVRGFARNYARYLGLDAAPLLDGIERLAGADQPDLSPIRNAD
                     GDLPSGGGGRRGSFPAGAVVAVLLVLLGVGWYFDWFRTEPPAALELQTEPAPAFAPAP
                     TERDNAASASSEPVAAPALAPLAPAETSAPAAAAGNPVANPPSAGASAQASAPASSAP
                     AGVISPAGASAPAGPGAPAGAAVPAPVSAPAAAPASSDAAAAAPDESAGGNRLSFRFG
                     GDSWIEVRDASGTILHSGTNRAGSSRVVQGTPPFRLVVGNSANVVLEQDGKAVDLAAH
                     TRGSVARLTLP"
     gene            complement(26558..27358)
                     /gene="pilW"
                     /locus_tag="P5537_06610"
     CDS             complement(26558..27358)
                     /gene="pilW"
                     /locus_tag="P5537_06610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus biogenesis/stability protein PilW"
                     /protein_id="HRV77751.1"
                     /translation="MKSTLAPAVLAVALALGGCAGAPGLPSGAATISRPMSDISPATP
                     ADARARVHVELGMAYFEVGRYDVALDEAKIALGDSPSYAPAYHLLGLAYMYVEEHGAA
                     RENFERALREAPGDPDFNNSYGWYLCSQGQEREGLERLALAARNPYYRYQTRPLTNAG
                     LCHLRLGEESAAEAQFQRAVQADPENAQALYLLADIAYRGGRYEQARSQLIRLHQAHG
                     PSAASAWLGLRTERRLGNADAEASYAAQLRSRFAESEEFKSMNQGKFE"
     gene            complement(27355..28503)
                     /gene="rlmN"
                     /locus_tag="P5537_06615"
     CDS             complement(27355..28503)
                     /gene="rlmN"
                     /locus_tag="P5537_06615"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HRV77752.1"
                     /translation="MSTPNPVNLLDFDVDGLVAWFAGLGEKPFRARQVMRWMHREGCD
                     DFDAMTDVAKSLRAKLKEVAVIRPPVPVRDSISADGTRKWLLDVGNANAVETVFIPET
                     SRGTLCVSSQAGCALDCAFCSTGKQGFNRNLSAAEIIGQLWLANKLLGAARADAGEAA
                     PDLEAGEKDNGRIISNVVMMGMGEPLANFDNVVTALRLMLDDHAYGLSRRRVTVSTSG
                     IVPAMDRLRDECPVALAVSLHASNDTLRDRLVPINQKYPLRELMAACQRYLERAPRDF
                     VTFEYVMLDGVNDSDAHARELVALVRDTPCKFNLIPFNPFPDSGFQRSPAERIRRFAG
                     ILIDAGIVTTTRKTRGDDVDAACGQLAGQVQDRTRRTVRLHQARENMR"
     gene            complement(28636..29061)
                     /gene="ndk"
                     /locus_tag="P5537_06620"
     CDS             complement(28636..29061)
                     /gene="ndk"
                     /locus_tag="P5537_06620"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012347891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0006165 - nucleoside diphosphate
                     phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HRV77753.1"
                     /translation="MAIERTLSIIKPDAVAKNVIGQIYARFEGAGLKIIAAKMVHLSE
                     QEAGQFYAVHKERPFFKDLVSFMTSGPVMIQCLEGENAIAKNRELMGATDPKKADKGT
                     IRADFAESIDANAVHGSDAPETAAVEVAFFFPGMNVYSR"
     gene            complement(29282..30568)
                     /locus_tag="P5537_06625"
     CDS             complement(29282..30568)
                     /locus_tag="P5537_06625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HRV77754.1"
                     /translation="MTNTIAIFGLLVVLMAIGMPVGVALGLTVLSFMFIFTDVPLESV
                     ALKMFTGIEKFEIMAIPFFILAGNFLTHGGVARRMINFATAMVGHLRGGLGMSAVLAC
                     ALFAAVSGSSPATVVAIGSILIPAMVKQGYPLRFGAGVVASAGGLGILIPPSIVMVMY
                     SVTTNSSVGALFMAGVIPGLLLAFMLGLCTWYVARKNNYPTLPVVSWAERIKHFRKAF
                     WGLMLIVVVMGGIYSGMFTPTEAAAMSAVYAFFIAVFVYKDLTFKQIPRVLLDSANMS
                     AMLLFIIASAVLFSFILTSEQIPQRMADAIVASGMGPIGFLIVVNILLLVAGALMEPS
                     SIILILAPILFPVAVALGIDPIHFGVMIVVNMEIGMITPPVGLNLFVASGITKAGLTE
                     MSKAVMPWLYTMLAFLMMVTYIPSISTFLPRALGMM"
     gene            complement(30581..31276)
                     /locus_tag="P5537_06630"
     CDS             complement(30581..31276)
                     /locus_tag="P5537_06630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HRV77755.1"
                     /translation="MNKLLDRLEEFIIAALMAVATIVIFISVVHRYASGYEIPVVQDW
                     LLDMNFGWAQEFCIILFVWMAKFGAAYGVRTGIHVGVDILINKLTGSSRAALIQIGLV
                     CGVIFTGLIGLFGALFVWENGMAYETLSLLGRDTGDFFEGPTTPDLEWPTWIVYSAVP
                     LGSFLMCYRFLQVMVSFARTGDLPTHDHGHVEGLDEEDDENVLLEGEAFSIAEDIEHA
                     RREAEAKRPGQGK"
     gene            complement(31353..32357)
                     /locus_tag="P5537_06635"
     CDS             complement(31353..32357)
                     /locus_tag="P5537_06635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HRV77756.1"
                     /translation="MKIRSLLVGLVAVGLSSVALAAEPIVIKFSHVVAQDTPKGKAAE
                     KFKALAEQYTNGAVKVEVYANSTLYKDKEEMEALQLGAVQLLAPSLAKFGPLGVREFE
                     VFDLPYIFDGYEALNKVTQGAVGQQLLAKLEPKGIRGLAFWDNGFKSFSANTPIKKPE
                     DLRGKKMRIQSSKVLEEQMREVKSLPQVMAFSEVYQALQTGVVDGTENPHSNLYTQKM
                     HEVQKHMTLTDHGYLGYAVITNKKFWDGLPAEVRTQLDKAMVESTVYANQIAKEENDK
                     SLEAVRASGKTEIHTPTAEEKAAFKKAFAPVHKKMESRIGAELIQSIYKETGFDPAKL
                     "
     gene            32552..>33006
                     /locus_tag="P5537_06640"
     CDS             32552..>33006
                     /locus_tag="P5537_06640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HRV77757.1"
                     /translation="MSSADTLQPTAPRVRRRWLQHLPYLSLALFLAAIAALVWLTREY
                     DDEAQRATLISDVLWMEQNLRFNLDRNEIHLQEIGPELLGAPTPSAQTEARLASLLTP
                     GRGLARILWLSPQGQVLGAMPPLAPARTAPDASADGTALPLDESSLQLAR"
BASE COUNT         4810 a        10989 c        11810 g         5397 t
ORIGIN      
        1 gtcgcgcgat ggtgaggccg cattcgcgcc tgccggcgct cctacagggg aacgcggcgt
       61 tcgcgcctgc cggcgctcct acaaaaaacg ccgcgcggcg cctggtgggg cgacgcgcgg
      121 cgtgcttgcg ggacggctgc ggcgggatta catgctgcgg cggtactggc cacccacctt
      181 gtacagcgcc tcggtgatct gccccagcga gcagtagcgc accgcgtcca ccagcacctc
      241 gaagacgttg gtgttgtcga tcacggcctg ctgcagcttg gcctgccact tgggcgcctc
      301 ggccttgttg cgggcgtgga agtcggcgag gcgcttcaac tggccctgct tctcttcctc
      361 ggtcgaacgc gcgagctcga tctcctgctg cgcctggccc ttcgggttga ggaaggtgtt
      421 cacgccgatg atcgggtagg agccgtcgtg cttcttgtgc tcgtagtaga gcgactcctc
      481 ctggatcttg ccgcgctggt agccggtctc catggcgccg agcacgccgc cgcgcgacgc
      541 gatggcctcg aactccttca acacggcctc ttctacgagg tcggtgagct cctcgatgat
      601 gaaggcaccc tggttggggt tctcgttctt ggccaggccc cactcgcggt tgatgatgag
      661 ctggatcgcc atcgcgcgcc gcacggactc ctcggtcggc gtggtgatcg cctcgtcgta
      721 ggcgttggtg tgcaggctgt tgcagttgtc gtagatcgcg atcagcgcct gcagcgtggt
      781 gcggatgtcg ttgaagtcca tctcctgcgc gtgcagcgag cggcccgagg tctgcacgtg
      841 gtacttgagc ttctggctgc gctcgttggc accgtacttg ttcttcatcg ccaccgccca
      901 gatgcggcga gcgacgcggc cgatcaccga gtattccggg tccatgccgt tgctgaagaa
      961 gaaggacagg ttgggcgcga agtcgtcgat gtgcatgccg cgcgcgaggt agctctcgac
     1021 gtaggtgaag ccgttcgaca gcgtgaaggc gagctggctg atcgggttgg cgccggcttc
     1081 ggcgatgtga tagccggaga tcgacaccga atagaagttc ttgacgtcgt gatggacgaa
     1141 gtactcctgg atgtcgccca tcatcttgag cgcgaactcg gtgctgaaga tgcaggtatt
     1201 ctggccctgg tcttccttca ggatgtcggc ctgcacggtg ccgcgcacgg tcgacagcgt
     1261 ccattccttg atcttctgca gctcgtcctc ggtgggctcg cggccgttgt cggccttgaa
     1321 cttgacgacc tgctggtcga gcgcggtgtt gaagaagaag gcgaggatga tcggcgccgg
     1381 gccgttgatg gtcatcgaca ccgaggtggt cgggcagcac aggtcgaagc cgtcgtacag
     1441 caccttcatg tcgtcgagcg tggcgatcga cacgccggag ttgccgatct tgccgtagat
     1501 gtccggacgc aggtcggggt cgcagccgta cagggtcacc gagtcgaagg cggtggacag
     1561 gcggtgcgcc ggcatgccct cggacacctt cttgaagcgg cggttggtgc ggaaggcgtc
     1621 accctcgccc gcgaacatgc gggtggggtc ctcgccctcg cgcttgaacg cgaacacgcc
     1681 ggcggtgtag gggaaggagc cggggacgtt ctccttcatc aggaacttga gcgtctcgcc
     1741 cgcgtcctcg aagttgggca gcgccacctt gcggatcttg ctgcccgaca gcgaggtgct
     1801 ggtgagctgg gtgcggatct ccttgtcgcg gatcttcacc acgtactcgt cggcggcgta
     1861 gagctcgcgg gtcttcggcc acatgtcgag cagtttcctc gcggccgggg tgagctcgcc
     1921 gtccttccag tcgatcatct cggcgaacga gccggcatcc ttgccgcact gctcgaacag
     1981 gcccttggcg atcttcagcg actggcgctc gcgcgcgacg cgggcctgct gctcgatgtg
     2041 cttgtggtag ccgcggacgg tgtcggcgat ctcggcgagg tagcgcgtgc ggtcggcggg
     2101 gacgatggcg cggccctcgg acgaggaacg caccttgacc accggcagct tgctcttggc
     2161 gaccttgagg cccttgccca cgagcgcggg cagcacggcc tggtacagcg cggtgacgcc
     2221 gtcgtcgttg aagcgcgcgg ccatggtgcc gaacaccggc atctcttcgg ggcgctggcc
     2281 gaacagctcg cggttgcgct ggtactgctt ggcgacgtcg cgcagcgcgt cgagcgcgcc
     2341 cttgcggtcg aacttgttga tggcgacgaa gtcggcgaag tcgagcatgt cgatcttctc
     2401 gagctggctg gcggcgccga actcgggggt catcacgtac agcgacaggt cgacgaaggg
     2461 cacgatcgcg gcgttgccct ggccgatgcc ggaggtctcg acgatgacga ggtcgaagcc
     2521 cgcgagcttg cacgcggcga tgacctcggg cagcgcggcc gagacttcgg agccggtgtc
     2581 gcgggtggcg agcgagcgca tgtagatgtt ggcgtgctcg atcgcgttca tgcggatgcg
     2641 gtcgccgagc agcgcgccgc cggtgcgctt gcgcgagggg tcgatggaga cgatggcgag
     2701 cttgagcttg tcgtcctggt cgaggcggaa gcggcgcaca agctcgtcgg tcagcgagga
     2761 cttgcccgcg ccgccggtgc cggtgatgcc gagcgtcggc accttggtct tggccgcggc
     2821 gtcgatgagg gccttcttga cctcgtcgcc gtagccgccg ttctcgagcg cggtgatgat
     2881 ctgcgccagc gcgcggcggt cgccggcggc gagcgccttg agcaccgcgt cggccttcgg
     2941 cggcgcggcc ttggtgacgt cgacgtcgca gcgctcgacg acgctgttga tcatgccctg
     3001 caggcccatc ttggcgccgt cttcgggcga gaagatgtgg gtgacgccgt attcgtggag
     3061 ttccttgatc tcggctggca cgatcacgcc gccgccgccg ccgaagacct tgatgtcctc
     3121 gccgccgttg gccttgagca ggtcgatcat gtacttgaag aactcgacgt ggccgccctg
     3181 ataggaggtg atcgcgatgc cctgcacgtc ttcctgcagc gccgcgttga cgatctcgcc
     3241 gaccgagcgg ttgtggccga ggtggatgac ctcggagccg gtcgactgca ggatgcggcg
     3301 catgatgttg atggacgcgt catggccgtc gaacagcgcg gctgcggtga cgaaacgcac
     3361 cttgttcttg ggcttgtagg gcgacagctt gtgcgcaacg ctcagatcgg tcatgtcgtt
     3421 cgtctccagg tgggtgtgaa catccctgca atcttagaag ggtcttcacg cctttgccat
     3481 tgcgcttgcc gacgcggatc gtgcaaaatc cgccaaaccg gtgcttctgg gtaggcgctg
     3541 cggcagctgc gaattcggcc accggaagaa atgacgcgca tgccgccccc ccacgcccgc
     3601 cttcgcgcct gccggcgctc ctacacaaac caccacgcgc cctggcgctc ctacctgaac
     3661 caccacgcgt cccggcgccc cttcatgaac caccacccgt cccggcccgc ctgtaggcgc
     3721 tgcggtagct gcgaattcgg ccaccggacg aaatgacgcg cctgccgacc cccacccccg
     3781 ccttcgcgcc tgccggcgct cctacaggaa ccattccgga ttcgtgatcc gctgaaccga
     3841 cccacaccga tgcccaatcc tgcagctccc cgtctccgtc gtggccgcgc cacggtcgct
     3901 cccggcttcg tcaccggcat gctggccggg ctggagcggc gcgggctcga cccggcaccg
     3961 ctgctggcgc gggccgggat cgaccttgca gaaaccgaca cccgcatccc ggtcgagcgc
     4021 tacgccctgc tctacaacct gtgcgtggag gcgctcgacg acgaggcctt cggcctgctg
     4081 ccggagccga tgcgcccggg cagcttcgag ttcctctgcc gcgcgctgct cggcgcaccc
     4141 acgctgggcg aggcgctgcg gcgcgcgatc cgcttcctgc gcatcgtgct gccggccttc
     4201 cgcatcgagc tgcgggtggc gggcgcgcgc gccgagttgc tgatcgacga tgacggcagc
     4261 ctcggccccg cgcgcgacgc ccccgcgcgc gtgttcgcct atgaatggct gctgcgcctg
     4321 ctgcacggcg tggcgagctg gttcgtggcg cgcgggctgg cgctcgacgc ggtcgcgttt
     4381 ccgtatgcgc gcccggcaca tgcggaggat tacgcgctgg tgtacaccga gcattcgagc
     4441 ttcgacgcgc agcggctgag cgcgcgcctg caggccaacc tgctggagct gccgctgcgc
     4501 cgcgacgagg cggcgctggt gggcttcctc gacggcgccc cgggcaagat caccacgctc
     4561 taccgtcgcg accgcgagat ggtctttcgc gtgcgcgaca tcctgcgcga cgcgctgccg
     4621 cagaacctgt cgctcgaaga ggtcgcggaa cgcctgcacg tgtcgccgcg caccctgcac
     4681 cggcggctcg aggaggaggg ctcgggcttt cgcaacatca aggaggccac ccgccgcgac
     4741 atcgcttacg cgcgcctggc caagacccgc cagcccatcg ccggcatcgc cgccgagctc
     4801 ggctacgccg acccgtccac cttctaccgc gccttcgtcg cctggtccgg cgtctccccc
     4861 gagcgcttcc gcgaccaggc caccggccgc aaaccacccc cgtagccggg gcggttcatg
     4921 taggagcgcc ggcaggcgcg aacgcggcct cgtcatcgcg cggttatgcc gaatgagagc
     4981 gctgcaccgc cagattcgcg gctgccgccg ctcctacagg aggctgcgat tcgtaccggg
     5041 cgtcgaggag cggaaacgcc ggggtgccgg ttcgtatcgg gcgtcgagga gctgaaacgc
     5101 cggggtgcca gttcgtgggg gcgtccaggg gcgggaacgc gtcgaatgcg cgccggttca
     5161 tgtaggagcg ccggcaggcg cgaacgcggc ctcgccgtca cgcgaccacg cccgctgaga
     5221 gcactgcacc gccagattcg cggcggccgc tgctcctaca ggtgcatcca gccacgaccg
     5281 cttctgcacg agcgccgcag ggcgcgaaga caacgcgcgc gtgagacggc ggcaactcca
     5341 ccggcggatg tgagcaatgg tcagatcctg atgcagcaac ctcccccctt cccccaaaac
     5401 ctccacgccc ccgcccgtgc attttgtgca accatcgccc gtaatcccct acggaggcga
     5461 atcgattggt cggcacggtg aagaacgacg acggcaacat cccgtattcg gcgctgtcgc
     5521 ccgagcagcg gcggcgctac gacctgctgc tcgcggggct ggacctgctc gaccaggcga
     5581 tcgcggtgtt cgacgcgacg cccaagctgg tcacctggaa caaggcgatg ctgcgcctgc
     5641 tcgacttccc cgagtcgatg gtgcgtgtcg gcaccccctt cgaggagttc gcccgtttca
     5701 acgccgagcg cggcgagtac ggccccggcg acatcgacac cctggtgcgc gcgcgcgtgg
     5761 cggctgcgcg cagcttccag ccgcactacg tcgagcgtgc ccgccccaac gggcgcatcc
     5821 ttgcggtgcg cggcgtgccc atccccaacc tgggcttcgt gtcgctgtgg accgacatca
     5881 ccgagcagcg ccgcgccgcg caactcatcg aggagcagaa cgcgcaactc gagaaccgcg
     5941 tgcgcgagcg caccgccgaa ctcgaggccg ccaacgcccg gctggcccag gccaacctcg
     6001 agatcgacga catcgctggc gcgctgcgcc gcagcgagaa ccgcctgcag ctgatcatcg
     6061 actcgatccc ggcgctgatc gcctatgtcg gcagcgacga catctaccgc ttcgccaaca
     6121 agggctacgc cgagtggttc ggcttcgcca aggacgccat catcgggcgc agcatcggcg
     6181 aggtcttcgg cgccgaggcc ttcgcgcaga tccagcccca tctcgagcgc gcgcgcgcgg
     6241 gcgagcgcgt gagctacgag tattcgcgca cgctggccga cgggcgcatg gtgcatgcgc
     6301 gcagcgtggt ggttcccgag ctcgacggcg acggccgcac ggtgggtttc ttcgtgatgt
     6361 cgatcgacat caccgagcag aaggcgagcc aggccgcgct ggtgcaggcg cagaagatgg
     6421 aggccgtggg ccagctcacc ggcggcttgg cgcacgactt caacaacctg ctcaccatca
     6481 tcatcggcaa cctttctgcg ctgcagcagc gcatcggcgc cgggccgggc gcggagttcg
     6541 tcgatccctc gctgcaggcg gcgcggcgcg gcgccgagct gatccgccgc ctgctgacct
     6601 tctcgcgccg gcaaccgctc gcccctactg ccgtcgaggt tggcgtgttg gtgcataaca
     6661 tgacccacct gctcgcgcgc accctgggcg agacgatccg catccacctg cgcctgcccg
     6721 gcgagccggt gcacgcgctg gtcgacccgc accagctcga gaacgccatc ctcaacctcg
     6781 cgatcaacgc ccgcgacgcc atgccggagg gtggcgagct gaccatcggg gtgagccgcc
     6841 gcgagctcga cgacgccctc gccgcggtgg tggaggtgcc gcctggcgaa tatgtgcaga
     6901 tcgatgtcgg cgataccggc aagggcatcg agccggccgt gctgcagcgc gtgttcgaac
     6961 ccttcttcac caccaaggat ttcggcagcg gcagcgggct ggggctgtcg atggtgtatg
     7021 gcttcgtgcg ccagtcgggc ggcaacatcc gcatccgcag cacgccgggg cgcggcacgc
     7081 acgtgcgctt cgtgctgccc acggcgacgg cggccgtgct cgcgcccgaa cgcgtcgcga
     7141 ccgcgacggc cggcacgcgt gcgctcgacg gtccggtgct gctggtggag gacgagcccg
     7201 aggtgcgcaa ggtggtgcgc atgcagctca ccggcctcgg ccacgccgtg atcgaggccg
     7261 ccgacggcgt cgaggcgctc gggctgctgc agcatgtcga cgacatcgcg ctgctggtga
     7321 gcgacaccgt gatgccgggc ggcatcggcg gccgcgagct cgcccggcgc gcgcgcgcgc
     7381 tgcggccgca gctgccgatc ctgctggtga ccggctacgc cagcgaagcg acgccgaccg
     7441 acgaactgcc cgccgacgtg ccgacgctgc gcaagccctt cgaccaagcg accctcgccg
     7501 cggcgctcgc caccctgctc ggtcccgaac cgggtgcggc gggcggggtc gaagccgcgt
     7561 ccccgactgc gccggccgcg gacggacagc cgcaatcccc tatcacgaac accaccacgg
     7621 agccccgccc gcaatgacgc agagccccac cgacccatcc caggcccgca tcttcgtgct
     7681 cgaggacgat cccgaggtcg cccgcctgat ctgcatgagc ctgggcgaat acggcttccg
     7741 ctgcgagcag atgcgcgccg gccgccagct gctcgagcgc gcgcgccagg tggcgcccga
     7801 cctctgcatc gtggacctcg gcctgcccga catggacggc atgcaggtgg tgcgcgagct
     7861 gcaggacggc agcccgtgcg cggtgctgat cctgaccggg cgcaacgatg tgaccgaccg
     7921 tgtgctgggc ctggagctcg gtgccgacga ctacatcgtc aagcccttcg aaccgcgcga
     7981 gctggtcgcg cgcgtgcgtt cgatcctgcg ccgctaccag cgcgccgcga gcgccgaacc
     8041 cgcgggcgaa cgcaacaccg cccgcttcgc cgggtggacc ttcgacgcca accgccacgc
     8101 cctggtcgca ccggacggcc gcgaggtctc gctctcggcc gccgaggccg gcctcctcgc
     8161 caccctgctg cgccgcccca acaagatcct gtcgcgcgaa cagctcctcg gcgagcgcga
     8221 cgtcgacccc ttcgaccgca gcatcgacgt ccgcatctcc cgcctgcgcc gcaagctcga
     8281 cgacgacccg cagaaccctc gcctgatcaa gacggtgtac ggcgcgggct atctgttttc
     8341 ggtgcaggtc gagtgggcat gacgccgaag accgccccct cccctgccga agcccgcacc
     8401 ccgcgccggt tcatgtaaga gcgccggcag gcgcgaacgc ggcctcgccg tcacgcgacc
     8461 acgccggcgg ccggctctgc accgccgaat tcgcggctgc cgccgctcct acaggggctg
     8521 cgggtcgtgt ggggcggcga ggggcgggac gcctcgggtg cgcgccgctt catgtaggag
     8581 cgccggcagg cgcgaatggg cgagcggcgg ccgccgcggc agtttgcagg cgcccctcct
     8641 tatccgaacc gccgccttcg cggcttgcgc cgtgcatgcc ggaatacggc cacgcgggtc
     8701 aggcgctgcg ctggcggcgg gactcgaaga ggcagatgcc gctggcgacc gagacgttga
     8761 ggctctcgac gctgccgtgc atgggaatgc gcgcgagctc gtcgcaggtc tcgcgggtga
     8821 ggcggcgcag gccgtcgcct tcggcgccga gaacccaggc gacgggcacc ttctggtcga
     8881 cctcgtagag cgtcttctcg gcctcgccgg cggcgccgac gacccacacg ccggcgtcct
     8941 gcatctcgcg cagcgcgcgc gcgaggttgg tgacggtgat gtagggcacg gtgtcggcgg
     9001 cgccgctggc gaccttgacg gcggtggcgt tgaggcccac cgcgcggtcc ttgggcgcga
     9061 ccacggcgtg ggcgccggcg gcgtcggcga cgcgcaggca ggcgccgagg ttgtgcgggt
     9121 cctgcacgcc gtcgagcacg aggatgagcg cgttctcgtc gaggctgtcg aggacgtcgg
     9181 cgagcttgat ctcgcgccgg gtggcatcga ccttggcgac cacgccctgg tggcggcggg
     9241 tgccgaccag ggcgtcgagc ttgtcgccct cgctctgggt gatgcgcacg ccggcggtct
     9301 cggcctgggc gaggaacttg cgcacgcgcg cgtccttgcg gtcggcggtg agaaagatct
     9361 cgagcaccgc gtcgggcacg tggcgcagct tggcggagac ggcgtggaag ccgtagatca
     9421 gccgggtggg cgtgttttca ggtgctttag ccacggtcgg agccctttgt agtggtcttg
     9481 cggccggcac gtcgggccgg ggccgggggc gcggattcta gcgcttcggc ggcgggcgcg
     9541 gcgggggttt cgaccgcggg gcttgcggtg gccttcttca cacgcttggc gcgcgattcg
     9601 ggcgcggcgg gctccggggc ggcgggcgcg gcctcgacca ccggcgtggc gacgggctcg
     9661 acggccgctt cggcggcggc cttcttcgca cgcctggcgc gcgacttggg tgcggtgggc
     9721 tccggggcgg cgggtgcggg ctcgaccacc ggcgcggcga cgggctcgac gaccgctccg
     9781 gcggctgctt tcttcgcacg cttgctgcgc gacttgggcg cggcgggctc cggggcggcg
     9841 ggcgcggcct cgaccaccgg cgcggcggcg ggctcgacga ccacttcggc ggctgctttc
     9901 ttcgcccgct tgctgcgcga cttgggcgcg gcgggctccg gggcggccgg cacggcctcg
     9961 accaccggca caggcagggc cacgccgcgc tcttccaccc cgcccttccg gctgcgcggc
    10021 ttgcgcgcct tcctgccttc ggcgggaacg gcctccacag ccgcggcttc cgcaaccttc
    10081 gccggagtct tggcctcgac cggcagcggc ccctcgatga ggcggaagtc gatcttgttg
    10141 gtcgccatgt cgacccgcac gagctgcacc ttgacgcggt cggagaggcg gaactgcttg
    10201 ccggtgcgct cgcccatgag cgcatgacgc gtctcgtcat agtggaagta gtcgctgccg
    10261 agatccgaga tgtgcagcag cccttcgatg aagatgtcgt cgagcgcgac gaagaggccg
    10321 aagggcacca ctgccgaaac gctgccggtg aactcctcgc cgacgcggtc ctgcatgaag
    10381 tagcacttga ggaaggcgac cacgtcgcgg gtggcgtcgt cggcgcggcg ctcggtcatc
    10441 gagcagtgca ggccgatctg ctcccagtcg ccggggcggt attgctcgcc gccgagcgcg
    10501 gccttgatgc cgcggtggat cagcaggtcg gggtagcgcc ggatcggcga ggtgaagtgg
    10561 gtgtaggact cgtaggcgag gccgaagtgg ccgacgttgt ccgggctgta catcgcctgc
    10621 ttcagcgagc gcagcatcac cgtctgcagc aactgggcgt cggggcggtc cttgacctgc
    10681 tcgagcagct tggcgaagtc gctcgcgcgc ggctcgtcgc caccgccgag ccccaggccg
    10741 aactccttga ggaactcgcg cagcttggcg agcttgtcct cggaaggcga gtcgtggatg
    10801 cggtacagcg ccggatgctc gcggctggcg agaaagtcgg atgcgcacac gttggcggcg
    10861 agcatgcact cctcgatgag gcggtgggcg tcgttgcgca cctcgggcac gatctgcgcg
    10921 atcttgccgt tgtcgtcgaa gatcatgcgg gtttcggtgg tctcgaagtc gatcgcgccg
    10981 cgcttggcac gcgccttcag cagcacgcgg aagagcttgt cgaggttctc gaggtggggc
    11041 agcaggggcg cgagttcggc ccgggtcgcc gcatcgttct cgtacagcgc cgccgcgacc
    11101 ttggtgtagg tcaggcgcgc gtgcgaccag atcaccgcgg ggtagaagcg gtagttcttg
    11161 atctcgccgg tggccgagat cgccatgtcg gccaccatgg aaaggcgctc gacctgcggg
    11221 ttgagcgagc acaggccgtt ggagagcttc tcgggcagca tcgggatgac gcggcgcggg
    11281 aagtacaccg agttgccgcg gtcgaaggcg tccttgtcga gcgcgctggc ggcgtcgaca
    11341 tagtgcgaga cgtcggcgat ggcgacgatc aggcggtagc ccttgccctg gcgctcgcaa
    11401 tacaccgcgt cgtcgaagtc cttggcggtc tccccgtcga tggtgacgag cggcagcttg
    11461 gtgaggtcct cacgcccggc ccagtccttc ttgcgcaccg cttcgggcag cttgcgcgtc
    11521 tgcgccttgg cctcgggcga gaactcgaag ggcaggtcgt gcttgcgcag cgcgatctcg
    11581 atctccatgc cggggtcggc atagttgccg agcacctcga cgatgcggcc gatcggctgg
    11641 gcgaacttgg tgggctgctc gaccagctcg acggtaacga tctggcccgg ctcgggcttc
    11701 ttgcgtccgc ccggggcgac caggatgtcc tgcgccaggc gacggttctc ggggacgacg
    11761 atcatcacgc cgtgctcgtt gatgatgcgg ccgacgacac gggtgttggc gcgctcgagc
    11821 acctcgacca gcttgccctc ggggcggccg cggcggtcgg tgccggagat gcgcaccatg
    11881 acgcggtcgc cgtgcagtac ctcgcgcatc tccttggggc cgaggaagac gtcgggctcg
    11941 ccgtcgtcgc ggcgcaggaa gccgaagccg tcgggatgac cctcgacacg tcccttgatc
    12001 aggtcggcct tggccggcaa caggtaggcg tcgcggcggt tgcgcacgac ctggccgtcg
    12061 cgctccatgg cgcgcaggcg gcggtcgaag aagtcgagct cgtgcggcgc gatgtcgagc
    12121 gcagcggcga gctcggagaa aggcatcggc acgccgcgct cggcgagaag ctgcagcacg
    12181 tactcgcggc tcggcagcgg gttgtcgtat tgctgggtct cgcgctcgta gaaggggtcg
    12241 gcgagacgca cggcgctggc ctgcgctgcg cccgccttgc gcgcggcccg gctgcgaccg
    12301 gcgccgcgca cgggcgagcc ggcgtggtgg gcggcggatt gggagctcgc gacggtgctg
    12361 cgggcgtcag gtgcggcagg ggcggaagac gcgccgcgcc cggccttgcg gcccgccgag
    12421 gtggcgcgcg gggcgtcctg ttgcgcggcc gcctgcgtct tgcgggagga tgcgccggag
    12481 cggggctgat cggttttttt cgttttgcga gtcattgaca atcttctttt cgtgcttata
    12541 atgcgcgtct tcttgcccag atggcggaat tggtagacgc actagtttca ggtactagcg
    12601 ccgcgaggcg tggaggttcg agtcctcttc tgggcaccag tttcacagga aagccgctct
    12661 tcggagcggc tttttttgtt tttgcgccgc ggccacgcgg gtggatggcc tggcgcgcgt
    12721 tcgacggccg attcgcggcg gccgccgcac ctacaggacg gccagcgcgg cctgcgaggc
    12781 gtttccgtgt gggagcgccg gcaggcgcga attgcgcttg ggcgcaggaa tgcggctggc
    12841 gagggctcga ctgcccgttc gcggctgccg ccgctcctac aggacggccg gcgagggctg
    12901 cgaggcaatc ccctgtagga gcgccggcag gcgcgaatga actccgaacg ggaacgacgt
    12961 gtgcaggttg agccacgcga tgcaaaaaag cctttgcgat agtgaaagcg tttgctatta
    13021 tgcgcgtccc tgcccagatg gcggaattgg tagacgcact agtttcaggt actagcgctg
    13081 cgaggcgtgg aggttcgagt cctcttctgg gcaccagttt cacaggaaag ccgctcttcg
    13141 gagcggcttt tttgtttttg ccccgcggcg acacgagtgg gcagggttgg cgcgcgctcg
    13201 acggccggct cgcggctgcc accgctcctc cagggcggcc ggcgggggct gcgaggcgct
    13261 cccctgcagg agcgccggca ggcgcgaatt gcggccgcgc ggggtgcgac gagtgctcag
    13321 gcgccaaagg ggtggcggcg gaggatggtc tcgtcgcgct cggggccggt ggagatcacg
    13381 tcgatcggga tctcgcagat ctcctcgatg cggtgcaggt aggtgcgcgc ctcctgcggc
    13441 agggcgtccc agctctgcgc gccgaaggtg gtgccgctcc agcccttcat ggtctcgtag
    13501 atcggctcgc agcgcatgac ctcttccgag cccatgggca gcaggtcgat gcgcttgccg
    13561 tcgagcatgt agccggtgca cagcttcagc tcctcgagcc cgtcgagcac gtcgagcttg
    13621 gtgatgcaca ggccggtgac gccgttgatg atgatcgagc gcttgagcgc ggccaggtcg
    13681 agccagccgc agcggcgctt gcgcccggtg acggtgccga actcgcgacc cttggtggac
    13741 atctgctcgc ccggcacgcc cttggtctcg atgtcgagct cggtcgggaa cggcccgccg
    13801 ccgacgcggg tgcagtaggc cttggtgatg ccgagcacgt agtgcaggcg gccggggccg
    13861 acgcccgagc ccgccgcggc ctggccggcg acgcagttgc tcgaggtgac gaagggatag
    13921 gtgccgtggt cgatgtcgag cagggtgccc tgcgcgcctt cgaacagcag cgagccgccc
    13981 gacttgttga tcgcgtacag ctcggcggag acgtcggcga ccatcggcag cagctcgtcg
    14041 gcgtcggcca tggcctggtc gaacacggac tggaaatcga ccggctcggc gccgagatgc
    14101 tgggtgagca cgaagttgtg gtactcgagg ttggccttca gcttggcggc gaagcgctcg
    14161 cggtcgaaga ggtcgtacac gcgcagcgcg cggcgggcga ccttgtcctc gtaggtgggg
    14221 ccgatgccct tgccggtggt gccgatcttg tcgccagccg acttggcggc ctcgcgggcg
    14281 cggtcgagcg cagcatggta gccgaggatg agcgggcagc ccgggcttac gcgcaggcgg
    14341 tcgcgcacct tgatgccgcc ggcctccagc gtgcggatct cggacagcag gtggtgcgcg
    14401 tcgaggacca cgccgttgcc gatgaagcag gccacgccct cgcggacgat gcccgagggc
    14461 accaggttca gcttgtattc ggtcttgccg acgaccagcg tgtggccggc gttgtgaccg
    14521 ccctggaacc gcaccacgcc cttggcgtga tcggtgagcc agtcgacgat cttgcccttg
    14581 ccttcatccc cccactgggt accgacgacg acgacgttct ttgccatttt cttactctcc
    14641 ctgtaacggc acgatcgccc agcgatcgcc ccgcttcacc agttgccggt cgcagccggc
    14701 ttcgttccaa gttccttcat gtccgggcag cgccaccatc acgatctcgc cacgggcgcg
    14761 cagcgcggag acctcggcgg cgagcgccgc gtcgtcgtcc gacggcgcca acaccgcacc
    14821 cgccggcgcg gccggcgcgg gcagatgcca ggcgagctcg cgcaggtcga ggctgaagcc
    14881 ggtggccggc cgtgcgcgcc cgaaggcctg gccgacgcgg tcgtagcggc cgccgagcgc
    14941 gagcgcggcg ggcgactcgg cgccgtaggc ggcaaacacc acaccgctgt gatagtgata
    15001 gccgcgcagg tcggcgaggt cgaagctcac cggcaggtcg cccagggcct cggcgagctg
    15061 gcgcagctcg gcgagcgggc cggcgatctc ggcgtcctgc ggcaggcggg cggcggcctc
    15121 ggcgagcacc tcggggccgc cgtagagttc cggcagtgcc agcagcgcgc tgcgcgccgg
    15181 ctcggggacg tccgcgagca cgcggcgcaa ttcgggcacg tccttcgcct gcagcaggcc
    15241 gaagagctct tcctcgcggc ccggcaccag ccctgcgcgc gcggcgagcg cgtggaagag
    15301 gccgacgtgg ccgatgtcga tgcgcgacgc gggcacttcg gcgaggcgca gcacctcggc
    15361 gagcaggcgc aggatctcga cgtcggcctc gatgccggca tggccgtaga gctcggcgcc
    15421 gagctgcagc ggctcgcgag tgccggtgag cgtggacggc agcgtgtgca gcacgctgcc
    15481 gcagtagcac agccgcgaca cgccgcgacg gttgagcagg tgggcgtcga tgcgcgtgac
    15541 ctgcggcgtc atgtcggcgc gcacgcccat gctgcggccc gagagctggt cgaccagctt
    15601 gaaggtgcgc agctcgaggt cctttccggc gccggtggtg agcgagtcga ggtattcgag
    15661 cagcggcggc atcacgagct ggtagccgcg caggcggaag gcgtcgagca gacggcggcg
    15721 caggctctcc agccggtggg cgtcggacgg cagggcgtcc tggatgtggt cgggcagtac
    15781 ccagcgcatg gcgatgtcag agaacgatga aaagcattgc aagccccgcc agcatggagc
    15841 tcagaccgat gaagcggatc tggccatcgg ccatgctggc gaggcggagg aaggtgtcgc
    15901 gccatgcggc gggcgcgatg aagggcagca ggccttcgat gatcaacatc agcgcgaagg
    15961 ccgtgaggag cgagcttgcc atgaagacgt cagttgcgcg gcgcgcctcc ggcatccttc
    16021 atgaagcgga agaagtccga gctcggatcg accaccagca catcgtcctt gcccgcgaag
    16081 ctggcgcggt aggcctcgag gctgcggtag aaggagtaga actcgcgatc cttgccgaag
    16141 gcgtcggcgt agatggcggt cgccttggcg tcgccctcgc ccttgacctc ctgcgcgctg
    16201 cggtaggcct cggcgatgat cacctcgcgc tggcggtcgg cgtcggcgcg gatgcgttcg
    16261 gcctcggcgg caccgagcga gcgcagctcg ttggccacgc gcttgcgctc ggcctccatg
    16321 cggcgataga ccgactcgga cacctcgttg ggcaggtcca cacgcttcag gcgcacgtcg
    16381 acgatctgca cgccgatggt gcgggcgtcg cggtcggcac gctcgcgcat ctgctccatg
    16441 atgttgtcgc gctcgccgga gacgacgtca tgcacggtgc ggcgaccgaa ctcctcgcgc
    16501 aggccggcgt tgaccgtctg cgtcaggcgg gtgcgcgcgc gcgcctcgtc gcccgccacc
    16561 gactcgtagt agaggcgcgg gtcgacgatg cgccacttga cgaagtggtc gaccagcacg
    16621 ttcttcttct cggaggtgat gaaacgctcg ggctcgggcg tgtccatcgt caggatgcgc
    16681 ttgtcgaagt agcgcacgtt ctggatgaag ggcagcttgg cgttgaggcc gggctcggag
    16741 atgacctcct tgacctcgcc gagctggaag acgatcgcgt actggcgctg gtcgacggtg
    16801 aacagcgaca tcgaggcgat cacgacgagc agcagcagcg tgccgccgat cagggacatc
    16861 ttgtcacgca tcaacgcact ccccgctcac gactgaacat tccttcccgg ttgcgcggat
    16921 cgaaggccgg caccggggcg ttggccgcga ggccggcggc cgactgcgag tcgggcggtg
    16981 gcgccgcggc gggcttggcg cccgtctgct gcatcagctt gtcgagcggc agcatcagca
    17041 ggttgccgtt gcccctggcg tcgaccatga ccttcgaagt gctcgacatg acctgctgca
    17101 tggtgtcgag atacaggcgc tcgcgggtca cctccggcgc gcggctgtat tcggtgaaca
    17161 cctgattgaa gcggctcgcc tcaccctcgg cgttggcgac cacgcgctcg cggtaggcgt
    17221 tggcctcttc gaccaggcgc gaggcggtac cccgcgcacg cggcacgacg tcgttggcgt
    17281 aggcctcgcc ctcgttcttc tggcgctcgc ggtcctggcc ggccttgacc gcgtcgtcga
    17341 acgcggcctg cacctgctcg ggcggctggg cgttctgcat ggtcacgcgg ctgacctgga
    17401 tgccggtctc gtagcggtcg aggatgcgct gcatgagctc gtgcgcggta gtcgcgatct
    17461 cctcgcggcc ctcgtagagc acgaagtcca ttcggctctt gccgacgatc tcgcgcatcg
    17521 cggtctcggc agcctgggcc acggcctcgt cggggaagcg gttgttgaag acgtagttct
    17581 ccgggctgtt gagcacgtac tgcacggcga actggatgtt gatgatgttc tcgtcgtccg
    17641 tgagcatcag cgactcgcgc agcaccttgt tgcgctcgga gccgcgatag cccacctcga
    17701 ccgtgcgcac gccggtgagg tcgacgatct cgtgggtctc gaagggcgcc ggcaggcgcc
    17761 agcgcaggcc gggctcggtg gtggcgacgt actcgcctag gcgcagcacg acggcgcgct
    17821 ggttggcgtc caccgtatac aggccgctcg ccagccagac cacgagcacc agcgccgcga
    17881 gcacgccgaa gccgccgcgg aactgcttga aggaaaagcc ggggagctcg gggcggttgc
    17941 cgccaccccc gccgttgccg ccgccgaagc cgctgccacg cccggagcgc ttgccgccga
    18001 acatgccgga gaggcgctgg ttgaaatcgc gccagacctc ctcgaggtcg ggcggtccct
    18061 ggttgccacc gcgattgcga tcgccgcgca ggtcgtcgtt gcggttgtcg tcgccgcgat
    18121 tgccgtcttc gcggtcgccg ccgccctggc caccccagcg tgggtcgttc agtgacatga
    18181 gaatgcctgt tatcacgttt cttgtcgtcg ctcgtcatcc gaaccggcgg gccggtcggc
    18241 gttgtcacca aaggtctgcc gagccacttc ggcaagcgcg tcgcgaagca gttcgaggcc
    18301 ttccccggtt cgggcgctca aaaaaatgcg cctgatggta ccacagtccc ccctctcgac
    18361 cgccgcggcg gcccgggtga gatcgatctt gttccacacc aggatctgcg gcacgtcggc
    18421 cgcgccgatc tcggcgagaa cctggttcac cgcctcgatc tgcgcgtcgc ggtcctcgct
    18481 cgccgagtcg acgacgtgca acagcagatc ggcctgcgcc gtctcctcga gggtggcctg
    18541 gaaggccgcc acgagggcgt gcggcaggtc gcggatgaag ccgacggtgt ccgacagcac
    18601 cacgctcgct cccgccccct cgccgccgac gtacaacctg cgcgaggtcg tgtcgagggt
    18661 ggcgaagagc tggtcggccg cgtaggcgcc cgccttggtc aaggcgttga acagcgtcga
    18721 cttgcccgca ttggtgtaac cgacgagaga gacagacaga acgtcgcggc gttcccgggc
    18781 gcgtcgacga accttgcgct gcttctcgat ctgggcgagc cgggacttga gcatcttgac
    18841 gcgattgccg agcaggcggc ggtcggtctc gagctgcttc tcgcccgggc cgcgcaggcc
    18901 gataccgccc ttctggcgct cgaggtgggt ccagccgcgc acaaggcggg tggccaggtg
    18961 ctcgagctgg gcgagttcca cctgcagctt gccttcgtgg ctgcgtgcgc gctgcgcgaa
    19021 tatgtcgagg atcagcgcgg tgcggtcgat gaccatgcac tgcagctcgc gctcgaggtt
    19081 gcgctgctgc gcgggcgaca gggcgtggtt gaagatgacg atgtcgccac cgtacgcgcg
    19141 cagcgcctcg ccgatctcct gcaccttgcc gctgccggcg aagagcttgg ggtcgggcgc
    19201 ggcgcggcgg ccttgcacga ccgcctcgac gctcgcgccg gcgctgagga caagcagctt
    19261 gagctcggac aggcgctcgt cgatggcacc ctggccgagg tcgagctgga cgaggaccgc
    19321 acgttcgccg gtggcggggc gctcaaacac gatgcgcgcc tcccgcggcc gacgggcatc
    19381 ggccgcgccg ggtggaccgc ggcctcagtt cgcgccctct tcctgctgga tgacgaccgg
    19441 gcgggcgggc acgacggtgg agatcgcgtg tttgtagacc atctgggtga cggtgttctt
    19501 gagcagcacg acgtactggt cgaaggactc gatctggccc tgcagcttga tgccgttgac
    19561 cagatagatc gacacgggga tgtgttcgcg acgaagggtg ttcaggaagg ggtcctggag
    19621 gagttgccct ttgttgctca ttgtggaacc tctatctatt gtgtttataa gaatgttatg
    19681 gacacgttgt gcactgccgc atggcagtat gcaacgaaac ccaggcgtgg aaacgggttc
    19741 ttctgcgaaa aaatgctcag ttccgcgtcg cgtatggatt gtgcgtggtg cggaactgga
    19801 tgcgcaaggg cgtgcccttg aggtcgaagg catcgatgaa gcagcgctcc aggtagcgca
    19861 cgtaggactg cgggatgtcg tcgagcgcgt tgccgtggat gacgatcacc ggtggattca
    19921 ttccaccctg gtgggcgtag cgcatcttcg ggcgcgccag cccgtggcgc ggcggcgcct
    19981 ggcgcgccac cgcctgctgc agcgcacgcg tcagccgcgg tgtggccagg ttggcggtgg
    20041 ccgcggcata ggcggcgtcc accgacttga gcagcccggc gatgccctcg gccttgagcg
    20101 cggagatctg gtggaagcgc gcgaaggaca ggaaggcgag cttgcgcgcg atgtcggcct
    20161 tgaggcggtc gcggcggtag tcgtcgaccg cgtcccactt gttgatcgcc accaccagcg
    20221 cgcgcccggc ctcgagcgcg aagccggcga tgtgggcgtc ctggtcggag atgtcctgcg
    20281 cggcgtcgag cacgagcacg accacgttgc actcctgcac cgcctgcagg gtcttgatga
    20341 cggagaactt ttccaccgcc tcgaagacct tgccgcgccg acgcaggccg gcggtgtcga
    20401 tgagggtgta gcgcttgccg ccacgctcga aggggatgga gatggcgtcg cgggtggtgc
    20461 ccggcatgtc gaaggcgatc acgcgctcct cgcccagcag ggtgttcacc agggtggact
    20521 tgccgacgtt gggacgcccg acgatggcga ccttggggcc ctcgtcgtcg gagtgctcct
    20581 tctcgtcgtc ggccggaaag ggcgcgagca cgagctcgac cagttgcttg acgccgtcgc
    20641 catgcgctgc ggagaccggc agcgggtcgc ccaggccgag cgcgtggaag tcggcggcga
    20701 ccatcgcgcg gtcgatgccc tcggccttgt tgacgaccag gtgcaccggt cgcccggcgc
    20761 ggcgcaggcg cgcggcgatg ttctcgtcgt gcggggtgcg cccggcgcga ccatcgacca
    20821 ggaacaacag cacgtcggcc tcggcgatgg cctgttcggc ctggcgcgcc atctcgtgca
    20881 tgatgccgtc cttggccacg gggtcgaagc cggcagtatc gacgaccagg tagtcgcggt
    20941 caccgacgcg gccgatgccg tagtggcggt cgcgggtgag gccgggctgg tcggcgacga
    21001 gcgcgtcacg cgtgcgcgtc aggcggttga acagggtcga cttgccgaca ttgggccggc
    21061 cgaccagaac gatggtgggt ttcacttgct gcggtacctc agcgtacttc gtacgcggtg
    21121 atgtcgccgc cggcaccctg caccacgaag ccgcggcgca gcgggaccgg atcggccacg
    21181 atcggatcac tgccggcgcg ttcgcgcgcg gcgaaggcgc cggtctcgcg cgagagcgca
    21241 tgcacataac cctcgaggtc gccgacaacc acgtagtcgc cgacgatcag gggacgggag
    21301 acctggcggc gcgcgagcgc gtcctgcttc catacgcttg cgccgctata ggcgtcgagc
    21361 gcatggacgg cgtcgcggtc gtcggtgatg agcgcgtagc gcgcgtcgcg gtccatgccg
    21421 acgctgctgg agaagtcgcg cgcccagatg gcgttgccgt tcgaggtgtc gaagcaggcg
    21481 gcgcggccct ggtaggcgac cgcgcacacc tcgcgacgac cgaccaccgg catgccggcg
    21541 acgtcggcga cgcgctcgag ctcggtggcc ccgcgcggca cggcgacgtt gagctcggtg
    21601 atcgcgccac cgttggcggc gttgatcacg gcgagcttgc ctccggggaa gccggcgagc
    21661 acgaccgggc cttcgagcac cacgccggcg aagctgcgca gcgccagcgg cgggttgttg
    21721 cgctgataca cccagcgccg gctgccgtca cgcgcgttga gcgcgatcag gcggttgtcg
    21781 gaggcgcgca cgatcaccag ctcgaggctg accgccggcg gcgccagcac ctcggcgccg
    21841 atcggcgcac gccagcgctc gctgccgttg tcggtatcga gggcgatcac cgtgccgtcg
    21901 gtggcgacca ccaccgcgag tcggccgtcg gtgccgacgc ccgcggagag ctcgctgccg
    21961 gtgtcgatcc gccacagctc gcggccatcc tcgaagcgcg cgacctcgcc ttcgttgccg
    22021 gcggcgaata cgctatcgct ccacaccgcg ggctggaagc ggtagtgctc ggcctcgccg
    22081 atgttcgcct gccacttggc cacgagctgc gcggcgggct tgaagtcgac cagcgccgcg
    22141 ggcttggggc cggaactggc gaaggggttc agcgaggagc aacccgcggc gagcagcgcg
    22201 gcggcgagca gcgggacgag acgcggcgtg ggggttttca tcgctcaggc tccgagggat
    22261 tcgagtttga cgcggacgac ctcgcgcaac gtgaccgcat cgtcacccgc ggcggtgagc
    22321 gcgtcgatcg cggcctggta ggcagcgcgc gcctccgcgg ccttgccctg ggcggcgagc
    22381 acgtcgccgc gcaggtcgtc gaagcgcgcc ttgtaggcgg ccgagggcgc ggcctgcagg
    22441 cgggcgagcg cggcgtcgag ctcgccctgc tgcagcagca ccgcggccag gcgcaggcgg
    22501 gcgagctcac gcagcgcggg gtcgctgccc ttttcggccg cccattcgag ctgggcgcgc
    22561 gcattgacga ggtcgccagc ctcgaactgc atcgccgccg acagcagcgc gccgagctgg
    22621 gcgctgacgc tgccgccgtg ctcgccgacc aggcgaccgg cggcctcgcg ggccttctgc
    22681 ggctcgttct tctccaccgc ctgctgcacc gcgtagtaca gcgcgccggc ctcgccggcg
    22741 ttgcggttct ggtaccagtt ccacgcctgc cagcccacgg aggcgagcgc cgccaccacc
    22801 gcgagggtga cgacgaagtt gccgtactgt gcccaccacg ccttgagttc ggaaatctgt
    22861 tcctgctctt cgagatcgta gaccgccatc atcaaacctc ttcttcgtct tcttcgggga
    22921 acatcagcgc ggccatcgcc tcgacgagct cgtcgatcgg cacgcgctgc tgggcgccgc
    22981 tgccgcgcag cggcttgagg ccgacctcac cggccgcggc ctcgtcctcg ccgatcacga
    23041 tcgccaccgg cgcctcgctg gcatcggcct tcttcatctg cgacttgaag ctgccgccac
    23101 cgcagtgcat cagcaccgcg aagccgtgct cgcgcagggt ctcggcggcg cggaagccga
    23161 ggcgctgagc ggcctcgccc acgctcacga catacacgtc gggcaccggg cgctcggcct
    23221 cgccgccgca ggccagccac agcaacagca ggcgctcgat gccgatcgcg aagccggcgg
    23281 ccggctgcgg cttgccgccg agctgctcga agaggccgtc gtagcgacca ccggcacaga
    23341 tcgtgccctg cgcgccgagg cgcgtggtga cccactcgaa cacggtgcgg ttgtagtagt
    23401 cgaggccacg gacgaggcgg tggttgatgc ggtaggggat gccggcgtcc ttgaggaaga
    23461 cctgcaccgc gtcgaagtgc gccttcgatt cgtcgccgag gtagtcggcg agcctcggtg
    23521 cggcttcgac gatcgcctgc agctcggggt tcttggtgtc gaggatgcgc agcgggttgg
    23581 tgtaaaggcg gcgcttgccg tcctcgtcga gcttgtcctg gtgctgctcg aggtaggcga
    23641 tcagcgcggc gcggtgctgc gcgcgctcct cgagcgagcc gagcgagttg atctcgagcg
    23701 ccacgtcctc gagcccgagg tcgtcccaca ggcgcgcgca catcaggatg agctcggcgt
    23761 cggcgtcggg gccggcgaag cccagggcct ccacgccgat ctggtggaac tggcggtagc
    23821 gccccttctg cgggcgctcg tggcggaaca tcgggccgta gtagtacagc cgctgcgggc
    23881 cgccggaggg gatcaggttg tgctggatcg cggcacgcac gcaggaggcc gtgccttccg
    23941 ggcgcagcgt gaggtgctcg ccgttgagcg cgtcctcgaa ggagtacatc tccttctcga
    24001 cgatgtcggt gacctcgccg atggcacgct tgaacagcgg cgtcggctcg accagcggca
    24061 tgcggatcgg gcggtagcca tagctctgca gccagtcgcg cacgatgtct tcgaagtatt
    24121 cccaggtttc ggcgtcggtc ggcaggatgt cgttcatccc gcgcacggcc tgcaaggtct
    24181 ggctcatggg gttctgttct tgtgtgtcgc gctcacgcgc ggtggtcgtt gttcgttgcg
    24241 gcgctcaggc gcccttcttc acgtatcggg tggcgatgta gttgtcgacg atcgccttga
    24301 actcggcggc gatgttgtcg ccgcgcaggg tcaccacctt ctcgccgtcg acgaacaccg
    24361 gcgccgcagg ggtctcgccg gtgcccggca gcgagatgcc gatgttggca tgcttgctct
    24421 cgccggggcc gttgaccacg cagcccatca ccgccagcgt catgttctcg acgccgtcgt
    24481 actgttcgcg ccacaccggc atctgcgcac gcacgtagtc ctggatgctc gatgcgagct
    24541 cctggaagaa ggtgctggtg gtgcggccgc aacccgggca ggcggtgacc atgggggtga
    24601 aggcgcgcag gcccatggtc tgcaggatct cctgcgcgac cacgacctcc tgcgtgcggc
    24661 tgccgcccgg ctcgggggtg agagagatac ggatggtgtc gccgatgcct tcctgcagca
    24721 gcacggcgag cgcagcggtg gagccgacga tgcccttgct gcccatcccg gcctcggtga
    24781 gacccaggtg cagcgcgtag tcgctgcggc gcgcgaggtc gcggtacacc gcgatcaggt
    24841 cctgcacgct ggagaccttg gcggagagga tgatgcggtc gcggccgagg ccgtattcct
    24901 cggccttggc ggcggattcg agcgcggaga cgacgagcgc ctcgcgcatc accgcgccgg
    24961 cgtcgcgcgg ctccgcacgc ttggcgttct cgtccatgat gcgcgcgagc accgactggt
    25021 cgaggctgcc ccagttgacg ccgatgcgca ccggcttgtc gtagcggcag gcgagctcga
    25081 cgatggcggc gaactgcggg tcgcgcttgc gaccggcacc gacgttgccc gggttgatgc
    25141 gcagcttggc gagcgcctcg gcgcaggccg ggaagtcggt gagcagcttg tggccgttgt
    25201 agtggaagtc gcccaccagc ggcacatcca tgttgagcgc gagcaggcgg tcgcggatct
    25261 tcggcaccgc ggccgcggcg gcctcgttat tgaccgtgat gcgcacgatc tcggagccgg
    25321 cgcgggcgag ctcggcgacc tgcatcgcgg tggcgagcac gtcggcggtg tcggtgttgg
    25381 tcatcgactg cacgacgacc ggggcttcgc cgccgatcct caccttgccg acgcgcacct
    25441 ggtgcgtgcg atggcgggcg agcgggctgg cttcgatcgg ctggagttcc gggtgaaggt
    25501 tcatggcgtt cggatcaggg aagcgtcagt cgggcgacgg aaccgcgggt gtgggctgcg
    25561 agatcgaccg ccttgccgtc ctgctcgagc acgacgttgg cggagttgcc caccaccagg
    25621 cggaagggcg gcgtgccctg gaccacccgg ctgctgccgg cgcgattggt gccggagtgc
    25681 aggatggtgc cgctggcgtc gcgcacctcg atccaggagt cgccaccgaa gcggaagctg
    25741 aggcggttgc cgccggcact ctcgtcgggg gctgcggcgg ccgcgtcgga cgacgccggc
    25801 gccgcggctg gagcactcac cggggccggg accgcggcgc ccgccggggc gcccgggccg
    25861 gccggagcgc tggcgccagc cggggagatg acgcctgccg gcgccgaact cgccggcgca
    25921 ctcgcctggg cgctcgcgcc cgccgaggga ggattcgcaa ccgggttgcc cgccgccgcc
    25981 gcgggcgcgc tcgtctccgc cggtgcgagc ggtgcgagcg cgggcgcagc caccggctcg
    26041 ctgcttgcgg aggccgcatt gtcgcgctcg gtgggcgcgg gcgcgaaggc gggggcgggt
    26101 tcggtctgca gttcgagcgc ggcgggcggc tcggtgcgga accagtcgaa ataccagccc
    26161 accccgagca gcaccagcag cacggccacc accgcaccgg cggggaagct gccgcggcgt
    26221 ccgccgccac ccgacggcag atcgccgtcg gcattgcgga tcggcgacag gtcgggctga
    26281 tcggcgccgg ccaggcgctc gatgccgtcc agcagcggcg ccgcatcgag gccgaggtag
    26341 cgtgcgtagt tgcgcgcgaa accgcgtacg aaggccatgc cgggcagcgc ggcaaagtcg
    26401 tcgttttcca acgcctcgat ctggcgcggg ctcagcttga tggcgaaggc ggcctcgtgc
    26461 accgattcgc cgcgtgcctc gcgcgcccgg cgcaggcgca caccgggcga gatggcggac
    26521 tcggcgccgg gggcaaggtg gtcggactgc atgctgctca ctcgaacttc ccttgattca
    26581 tcgatttgaa ctcctccgat tcggcgaagc ggctgcgcag ctgcgcggca tagctggcct
    26641 cggcgtcggc gttgccgagg cggcgctcgg tgcgcaggcc cagccaggcg gaggccgcgc
    26701 tcggcccgtg ggcctggtgc aggcggatga gctgggagcg cgcttgctcg tagcggccgc
    26761 cgcggtaggc gatgtcggcg agcaggtaga gcgcctgggc gttctccggg tcggcctgca
    26821 ccgcgcgctg gaactgcgcc tcggcggcgg actcctcgcc gaggcgcaga tggcaaaggc
    26881 cggcgttggt gagcgggcgc gtctggtagc ggtagtaggg gttgcgcgcc gccagcgcca
    26941 ggcgctcgag gccttcgcgt tcctggccct gcgagcacag gtaccagccg tagctgttgt
    27001 tgaagtcggg gtcgccgggg gcctcgcgca gcgcacgctc gaagttctcg cgcgcggcgc
    27061 cgtgttcctc gacgtacatg taggcgagcc cgagcaggtg gtaggccggc gcataggacg
    27121 ggctgtcacc gagcgcgatt ttcgcctcgt cgagcgcgac gtcgtagcgg ccgacctcga
    27181 agtaggccat gccgagctcc acatgcacgc gggcacgcgc atcggccggg gtggccgggc
    27241 tgatgtcgga catcggccgg ctgatcgtcg cagcgcccga gggcaggccg ggcgcgcccg
    27301 cgcagccgcc gagcgcgagc gccaccgcca gcacggcggg tgccagtgtc gatttcatcg
    27361 catgttctcc cttgcctggt gcaggcgcac ggtgcgccgc gtcctgtcct ggacctggcc
    27421 ggcgagctgg ccgcacgccg cgtcgacatc gtcgccacgc gtcttgcgcg tggtggtcac
    27481 gatgccggca tcgatcagga taccggcaaa acggcggatg cgctctgcgg gcgagcgctg
    27541 gaagccggag tccgggaagg ggttgaacgg gatcaggttg aacttgcacg gcgtgtcgcg
    27601 caccagggcg acgagctcgc gcgcgtgggc gtcgctgtcg ttcacgccat cgagcatcac
    27661 gtactcgaag gtgacgaagt cgcgcggcgc gcgctcgaga tagcgctggc aggcggccat
    27721 cagttcgcgc agcgggtatt tctggttgat cggcacgagg cggtcgcgca gcgtgtcgtt
    27781 ggacgcatgc agcgacaccg ccagcgccac cgggcattcg tcgcgcaggc ggtccatcgc
    27841 cggcacgatg cccgaggtcg acaccgtgac gcgccggcgc gacaggccgt aggcgtggtc
    27901 gtcgagcatc aggcgcagcg cggtgacgac gttgtcgaag ttggcgagcg gctcgcccat
    27961 gcccatcatc accacgttgc tgatgatgcg gccgttgtcc ttctcgccgg cctcgaggtc
    28021 cggcgccgct tcgcccgcgt ccgcccgcgc ggcgccgagc agcttgttgg ccagccagag
    28081 ctggccgatg atctccgcgg ccgacaggtt gcggttgaag ccctgcttgc cggtggagca
    28141 gaacgcgcag tcgagcgcgc agcccgcctg cgaggacacg cacagcgtgc cgcggctggt
    28201 ctcggggatg aacacggtct cgaccgcgtt ggcgttgccc acgtctagca gccacttgcg
    28261 cgtaccatcg gccgagatcg agtcgcgcac cggcaccggc gggcggatca cggcgacttc
    28321 cttcagcttg gcgcgcaggg acttggcgac gtcggtcatc gcgtcgaagt cgtcgcagcc
    28381 ctcgcgatgc atccagcgca tcacctggcg ggcgcggaac ggcttctcgc ccagcccggc
    28441 gaaccaggcg acgagaccgt cgacgtcgaa atcgagcaga ttgaccggat tgggagtgct
    28501 catgcctgaa acttcacctc tcgggagcgg aggcccgcaa tgacgggccg accgtaatgc
    28561 aaacggcccg cacacgccgc gcgcggtgcg ggaggcaccg cgaagcgtgc gcgacgggcc
    28621 gtcggtacgg accgctcagc gcgagtaaac gttcatgccc gggaagaaga aagccacttc
    28681 cacggcagcg gtctcggggg cgtcggagcc gtgcacggcg ttggcgtcga tcgactcggc
    28741 gaagtcggcg cggatggtgc ccttgtcggc cttcttcggg tcggtggcgc ccatcagctc
    28801 gcggttcttg gcgatcgcgt tctcgccttc caggcactgg atcatcaccg ggccggaggt
    28861 catgaaggaa accaggtcct tgaagaaggg acgctccttg tgaacggcgt agaactggcc
    28921 ggcttcctgc tcggacaggt gcaccatctt ggcggcgatg atcttgaggc cggcgccttc
    28981 gaagcgggcg tagatctggc cgatcacgtt cttggcgacg gcgtcgggct tgatgatgga
    29041 gagggtgcgt tcgattgcca tggaaaactc cgggacttcg cttggataaa gcgtgaggtt
    29101 tggaaaaaag cgcgaaattt tagcaggttt cgcgcgacac cgatgcgcgt gctcggcgcc
    29161 ggaatgtaag gcggcgcaag caccgcgacg aaaaacacga tccccgccgg catcgctgca
    29221 cggcggggat cgatccagcc tgcctgccgg ggccgtgcgc gacggtcccc ggcggctgcg
    29281 cttacatcat gcccagcgcc ctgggcagga aggtggagat gctcgggatg taggtgacca
    29341 tcatcaggaa ggcaagcatc gtgtacagcc agggcatcac tgccttgctc atctcggtga
    29401 ggccggcctt ggtgatgccg ctcgccacga agaggttcag gcccaccggc ggcgtgatca
    29461 tgccgatctc catgttcacc acgatcatca cgccgaagtg gatcgggtcg atgccgagcg
    29521 ccaccgccac cgggaacagg atcggagcga ggatcaggat gatcgaggac ggctccatca
    29581 gcgcgccggc caccagcagc aggatgttca ccacgatcag gaagccgatc gggcccatgc
    29641 cgctggcgac gatcgcgtcg gccatgcgct gcgggatctg ctcgctggtc aggatgaagg
    29701 agaacagcac cgcgctggcg atgatgaaca gcagcatcgc gctcatgttg gccgagtcga
    29761 gcagcacgcg cgggatctgc ttgaaggtca ggtccttgta cacgaacacc gcgatgaaga
    29821 aggcgtacac cgcgctcatc gccgccgcct cggtcggggt gaacatgccc gagtagatgc
    29881 cgcccatcac cacgacgatc agcatcaggc cccagaaggc cttgcggaaa tgcttgatgc
    29941 gctcggccca gctcaccacc ggcagcgtcg ggtagttgtt cttgcgcgcc acgtaccagg
    30001 tgcacaggcc gagcatgaag gccagcagca ggccgggaat gacgcccgcc atgaacagcg
    30061 cgccgaccga ggagttggtc gtgaccgagt acatcaccat gacgatcgag ggcgggatca
    30121 ggatgccgag gccgccggcc gaggccacca cgccggcgcc gaagcgcagc ggatagccct
    30181 gcttgaccat cgccgggatc aggatcgagc cgatcgccac caccgtcgcc gggctggaac
    30241 ccgacaccgc ggcaaacagc gcgcacgcca gcaccgccga catgcccagg ccgccgcgca
    30301 ggtggccgac catggcggtg gcgaagttga tcatgcgccg cgccacgccg ccgtgggtca
    30361 ggaagttgcc ggcgaggatg aagaagggga tcgccatgat ctcgaacttc tcgatgccgg
    30421 tgaacatctt gagcgccacg gactccagcg gcacgtcggt gaagatgaac atgaagctca
    30481 gcaccgtgag gccgagcgcc acgcccaccg gcatgccgat cgccatgagg acgacgagca
    30541 gaccgaagat tgcaatcgtg ttggtcatga tgtcgccccc ttacttgccc tggcccgggc
    30601 gcttggcctc ggcctcgcga cgggcatgtt cgatgtcttc ggcgatcgag aaggcttcgc
    30661 cctcgagcag cacgttctcg tcgtcttcct cgtccaggcc ttcgacatgg ccatggtcgt
    30721 gggtgggcag atcgccggtg cgcgcgaagc tcaccatcac ctgcaggaag cggtagcaca
    30781 tcaggaagga gccgagcggc accgcggaat agacgatcca ggtcggccac tcgaggtcgg
    30841 gcgtggtcgg cccctcgaag aagtcgccgg tgtcgcggcc gagcagactg agcgtctcgt
    30901 aggccatgcc gttttcccac acgaagagcg cgccgaagag gccgatgagg ccggtgaaga
    30961 tcaccccgca caccaggccg atctggatga gcgctgcgcg cgagctgccg gtgagcttgt
    31021 tgatcaggat gtcgaccccg acgtggatgc cggtgcgcac gccataggcg gcgccgaact
    31081 tggccatcca cacgaagagg atgatgcaga actcctgcgc ccagccgaag ttcatgtcga
    31141 gcagccagtc ctggaccacg ggaatctcgt agccggaggc gtagcggtgc accaccgaga
    31201 tgaagatcac gatcgtcgcg actgccatca gcgcggcgat gatgaactcc tcgaggcggt
    31261 cgagaagctt gttcatgatt gttttccccc gaaaaaacgc ccgtcgctct ctgcgagccg
    31321 gacgggcgct gctgggtgtg gagacgagag gattacagct tggccgggtc gaagccggtt
    31381 tccttgtaga tcgactggat cagctcggcg ccgatacgcg actccatctt cttgtgcacc
    31441 ggagcgaagg ccttcttgaa ggcggccttc tcctcggcgg tcggggtgtg gatctcggtc
    31501 ttgcccgagg cacgcaccgc ttccagcgac ttgtcgttct cttccttggc gatctggttg
    31561 gcgtagacgg tcgactcgac catggccttg tcgagctgcg tgcgcacctc ggccggcagg
    31621 ccgtcccaga acttcttgtt ggtgatgacc gcgtagccca ggtaaccgtg gtcggtcagc
    31681 gtcatgtgct tctgcacctc atgcatcttc tgggtgtaga ggttggagtg cgggttctcg
    31741 gtgccatcga cgacgccggt ctgcagcgcc tggtagacct cggagaaggc catcacctgc
    31801 ggcagcgact tgacctcgcg catctgctct tcgagcacct tggacgactg gatgcgcatc
    31861 ttcttgccgc gcaggtcctc gggcttcttg atcggagtgt tggccgagaa ggacttgaag
    31921 ccgttgtccc agaaggccag accgcggatg cccttgggct cgagcttggc gagcagctgc
    31981 tggccgaccg caccctgggt gaccttgttc agggcctcgt agccgtcgaa gatgtagggc
    32041 aggtcgaaga cctcgaactc gcgcacgccg agcgggccga acttggccag cgacggcgcg
    32101 aggagctgga cggcgcccag ctgcagggcc tccatctctt ccttgtcctt gtacagcgtg
    32161 ctgttggcgt acacctcgac cttgaccgcg ccgttggtgt attgctcggc gagcgccttg
    32221 aacttctccg cggccttgcc cttgggcgtg tcctgggcca cgacgtggct gaacttgatc
    32281 acgatgggct cggccgcgag cgcgacgctg gacagaccga cggcgaccag accgaccaga
    32341 agcgaacgaa tcttcatgaa gcacctcctc ctagagaaca gcatcggggt attgttcggc
    32401 cgcccggggc atcccgggtg gcgcgctcgc actgcgataa gtttcgctgt gtcgggcatc
    32461 agtatcgttt cggcccaatg cgcctgctat tgtggatgtc cgcatccgtg acaaccgcag
    32521 ccgggcgtac cgacgcctcc tccacagaac gatgagctcc gccgacaccc tgcaaccgac
    32581 cgcaccccgc gtccgccggc gctggctgca gcacctgccc tatctgagcc tggcgctctt
    32641 cctcgccgcg atcgccgcgc tggtgtggct gacccgcgag tacgacgacg aggcccagcg
    32701 cgcgactttg atcagcgacg tgctgtggat ggagcagaac ctgcgcttca acctcgaccg
    32761 caacgagatc cacctgcagg agatcggccc ggagctgctc ggcgcgccca cgccgtcggc
    32821 gcagaccgag gcgcgcctgg ccagcctgct gacgcccggg cgcggcctcg cacgcatcct
    32881 gtggctgtct ccgcaaggcc aggtgctcgg cgcgatgccg ccgctcgccc ccgcccggac
    32941 cgcgcccgac gcctccgccg acggcaccgc gctgccgctc gacgaatcca gcctgcagct
    33001 ggcgcg
//
LOCUS       DAOTIN010000030        32212 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_1555_length_32212_cov_8.976148, whole genome shotgun sequence.
ACCESSION   DAOTIN010000030 DAOTIN010000000
VERSION     DAOTIN010000030.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 32212)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 32212)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32212
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1555_length_32212_cov_8.976148"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(156..3449)
                     /locus_tag="P5537_06645"
     CDS             complement(156..3449)
                     /locus_tag="P5537_06645"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HRV77758.1"
                     /translation="MPLPLLDRSRRWRRASLTTRISFLATTLTTIVLMPALLVSWAAL
                     HALMLEKLGYELEATASEARLRFEARLEADIGKILDASRQTIFSHALSDPAGRAQYIR
                     PTLHDLCRATPELAALFLADFRGKVLEQGCAREDISAADFASTSALRQEAVERSTAQF
                     ALAHGSEQLRLRIAAPVIHLPTGNPEGALGAELELARTFDTSTAGVARGHTLRLRDLA
                     GTPTAQAGLADTGRELRYLTRLTGHHGLPLAIEVVVDRELALRPVRGLLAGMVVIGTI
                     VLMLALLLIRRIAHDIGAPLAELELTAARVEAGDLDALPPPRAGVDDADRFEVLANTV
                     YRMIASLRDTQQRLSATLEARTRQVERAEAERRLKERALASSTTGVLIVAHRPADEAR
                     VQYANPALLEMTGLAADAILGARWPALLFGKEPGPAPDRPAELAWRRADGVQVFMELS
                     TSRVIDAETGTETHAIVLVSDVSERLRADRAHRRLLESLGEVVVEVGLDGRLNFLNQA
                     WEKITGHLIEDSLGHAYTDFMHPDDLRRNLQALTALRQGELENHEFECRVRCRHGATR
                     WLSVKLNTLRDEERITGFAGILTDITERREAAMEIAIRDRALEAVGSGISIIDMRQPD
                     CPTIYVNRAFEHITGYARSEAIGRNCRFLRGSDHDQPEVAMLRRAISAGRPCEVTLRN
                     YRKDGSFFWNQLAVAPVVDPASDEVTHYVGVQADVTARRQSEDQLIDWLSRLDVIFTL
                     NPDAVVCFDNAGTVSFANAAAETLFAPAAGALIGSTVAEFRQRLAQLADPAQPFTPLA
                     DDELDLSPTNAPLDFAREGLIHLVHPRRCTLHQSFRECGTDATSQVIYFRNVTREVEL
                     DRMKSDFLATAAHELRTPMASIMGFSELLMMRSYSAEKTRELLGTINTQAQRLTGLLN
                     DLLDLARIEARRARSFQFETLPAGPLLEEALSGFLVPAESHRLVARIPPDLPSIRADR
                     AKFQQTVLNLLSNARKFSPHGGDIEVEVVAEHPDGLGLIGISVRDHGIGMSAADATHA
                     FERFYRSDRSGHIPGTGLGLPLVKEIMKLHGGSVSLESTPDIGTCVTLWFPVAAQGTA
                     ATRSGLAAP"
     gene            complement(3468..4673)
                     /locus_tag="P5537_06650"
     CDS             complement(3468..4673)
                     /locus_tag="P5537_06650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HRV77759.1"
                     /translation="MSLAPGGRRDFLHACTASLLACALPGRAFGRAAPVLIGVDAEFM
                     DPNSTADDAILFGARAAIEDLNAHGGVLGGRPLQLVITDNRSVPARGVANIEHLGAQP
                     DVVGFLCGKFSPVVLEQVPTLHALRLPLLAPWAAADAIIDNGREPNYAFRLGLSDTLA
                     IEALLGEIERRKLRRIGLLVPQTAWGRSCQYAAERHVGARTRDRLEIVGIEWHRWGAH
                     DSIPHSYRTLLEIGAEAILLVANEPEGATLVKAMASMATRDLRPLFSHWGISGGRFPR
                     LCGEALHKVQLDVAQSFSFARARGEDGARLARRAMQHFGTDSPLAVPSQTAIGPAYDL
                     VRLLAMAVDQTGGTHRPAIREALERLPAHEGVVRRHAPAFTPARHEGLGKDEVLLCRF
                     DSTGLLQPH"
     gene            complement(4670..5053)
                     /locus_tag="P5537_06655"
     CDS             complement(4670..5053)
                     /locus_tag="P5537_06655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV77760.1"
                     /translation="MNTILLVVEDQPEIRKLICMTMDYDGFEVHEADNGDTGLRMVKA
                     LRPHIVLLDVMMPGQLDGIQVCERIRADPEIAHIPVVMLTARSQQTDLEAGRRAGCNA
                     YLTKPFSPLQLIETVERLAAAETGR"
     gene            complement(5145..6038)
                     /locus_tag="P5537_06660"
     CDS             complement(5145..6038)
                     /locus_tag="P5537_06660"
                     /inference="COORDINATES: protein motif:HMM:NF014069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing phosphohydrolase"
                     /protein_id="HRV77761.1"
                     /translation="MNTSAHPAAASSTLLLQEPIELDDDSLPGIAANPRAPAASCDES
                     APARRPGDPYRQLYRVLHDLRTVVTQRDREREAMRRLQRESIARLALAAARGRREALE
                     HGLRVGATAALIGHALGSPLAWCDDLSDAARVHDIGNLAVPEAILAKPGSLDPQEWAA
                     IRRHPLDGARILGVASDPLHALAAEVALNHHEKWDGSGYPAGREGSNIPLSGRIVAVA
                     DFVDALGSRASYRDALDEGAIFALLDLAAGMQFDPAVVAAMHRIRPQLPQLRKRAALH
                     AARAGAGSPPPHWWRTLAALS"
     gene            complement(6035..7174)
                     /locus_tag="P5537_06665"
     CDS             complement(6035..7174)
                     /locus_tag="P5537_06665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004360754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HRV77762.1"
                     /translation="MNPAIQILFNRLSDSLAIIAPDGKVRFANEGMLALLPVRLGEPV
                     PHATIAAVLDQALTGHIPLPHAFESEIVHPTQVAAPDQLAGHIVRSPAGKDLVLVLRN
                     MTEASVYQTTIDNLCALIEHSMLEPLQRFAEDFGELLDEAARLPAAATTETAPRARDI
                     ERGQLLMQQLLDLVHLVQLGSGRPLQADDRIELADWLPRLLARHEPAAHARGQRLNLV
                     SPATGSFPVIYGSAHWLGLAFDACIDNALEHSDNGTDISLTLSASAAFVRITLRNRGR
                     GLRSPLLRARLMQPLMRSAAATARAPGLGLGLPLARRIVEMHHGRLALDQELDGFVTA
                     AIELPTSASPFTTVETDIAQAQRYASDLARLMTRRSRPAGEDVAR"
     gene            7413..9047
                     /locus_tag="P5537_06670"
     CDS             7413..9047
                     /locus_tag="P5537_06670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004360756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HRV77763.1"
                     /translation="MLIVVLAFTLVASVWAAVLFKVAAEERAELAAIERRTTNLARVF
                     EEHTVRTLASVDQALLFVKFQYEKVGAALDIASAVEQGMIVSTLFNQVGVIDAQGIYS
                     LSNLPGFKRVDLSDREHFRVHVDADSRNFFVSKPVLGRASGKWSVQLTRRINRADGSF
                     GGVAVISLDPFYFTTFYSDLDLGRHGVVTLVGLDGIVRARRAGDVTDVGQDIRRGALF
                     AELAKAPQGHYHSSSAIDGRVRIVSYRSLPGLPLVVLVGVDADEAMSDFRVRRGGYLA
                     FAAGMSLVIAAFCALSLWLLQRQRRISMRLREMKPRAESANRLKSEFLASVSHELRTP
                     LNGVIGYSELLMELAQDEEQRSYARVILDSSGHLLELLNSILDLARVEAGQMAIRLAP
                     EDVAGMVGQVCANYRPVAQAKGVTLACEAPAGVMLECDRTRLVQVLNNLVHNALKFTD
                     SGRVSVHARLTPTHCVFEVADTGCGIAPDQLEAIFERFRQVHDFETRAHGGTGLGLAL
                     CKELAELMGGGIEVRSTPGEGSVFSVRLPRSPKGTE"
     gene            9044..9439
                     /locus_tag="P5537_06675"
     CDS             9044..9439
                     /locus_tag="P5537_06675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004360758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV77764.1"
                     /translation="MMKVLVVDDNPINRLLPIAWLKRLGCETEESAGGTDALDKLATG
                     GFDVVLLDLSMPEMSGTEICRRARAMPAGGKIRIIAYTAHAAPEAFESFRSAGFDDVL
                     VKPVTRDALLGVFGGLEGFEDMRTPGAAG"
     gene            complement(9480..10412)
                     /locus_tag="P5537_06680"
     CDS             complement(9480..10412)
                     /locus_tag="P5537_06680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HRV77765.1"
                     /translation="MNDEHQTLAASAAAVPVAQPGIRPDPRSDGEFLLALGKRVRETR
                     DRRGQTRKQLAREAGVSERHLAHLEAGEGNVSIVLLRHIGGALGLPLPELLNLGVEES
                     VEQRLVRRILEQLPRHRLEDVIFRLMRDYGQEEAARRNRIALIGLRGAGKTTLGRRLA
                     AELGFRFVELDAEIERETGMPMGEIFALYGQSGYRRIEQRCLRRALDSGERTVLATGG
                     GIVSQTETYDLLLSRCLTIWLRASPEEHMQRVSAQGDLRPMAGSAEAMEDLRRILAAR
                     EAQYMRADHVVDTSGQGEDESFRALRAAVVDRGA"
     gene            10790..12376
                     /locus_tag="P5537_06685"
     CDS             10790..12376
                     /locus_tag="P5537_06685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004266041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016405 - CoA-ligase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate-CoA ligase family protein"
                     /protein_id="HRV77766.1"
                     /translation="MHTLSTADHGCTPPRIEIPDPYNAADDLLGRNLVAGRGGKVAYI
                     DDAGEYTYDQLAARANRCGNALLGTLGLARGDRVLMCVLDCIDFPAMFLGAIKAGVVP
                     IAVNTLLTERDYEYMLSDSGARVAVVSQALLANFAALPGRVPTLERLVVAGGDDDDGL
                     EALLSAQSDQLDAAPTRATDPCFWLYSSGSTGAPKGTVHIHSNLIHTAELYGQEVLGI
                     REQDVVFSAAKLFFAYGLGNGLTFPLSVGATAVLMAERPTPDAVFRRLREHQPDIFYG
                     VPTLYAGMLAHTGCPTAGELKNLRACTSAGEALPEGVGRRWKERLGVDILDGIGSTEM
                     LHIFLSNRAGDVQYGTSGTPVPGYRVRLVDEAGEEVTAAEEPGELQISGPSSAVQYWN
                     QPEKSRATFLEGWTRSGDKYYRNRDGYYVYSGRSDDMLKVSGIYVSPIEVESALIAHE
                     AVLEAAVVGIEDEERLIKPKAFVVLKPGFGPGEAMRQELQAHVKGMLAPYKYPRWIEF
                     VEDLPKTATGKIQRFKLRGI"
     gene            12438..13625
                     /locus_tag="P5537_06690"
     CDS             12438..13625
                     /locus_tag="P5537_06690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004360762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HRV77767.1"
                     /translation="MVGKDRKLRLAVSALGLGLGMLLAQGAAEAADKVKVGLMLPYTG
                     TYASLGNAITNGFKQYVAEQGGKLGGREVEYFVVDDESDAAKATENANKLVKRDNVDV
                     LVGTVHSGVALAMAKVARDSKTLLIIPNAGADELTGPLCAANVFRTSFSAWQPAHAMG
                     KVVAERGHKNVVTLSWKYSFGEQSVAGFKEAFEQAGGKVVKELYLPFPNVEFQPFLTE
                     IANLKPDAVFVFFSGAGAAKFVKDYEASGLKANLPLYAPGFLTDGTLDAMGGAGEGLL
                     TTLHYADGLDNAKEKAFRSGYVAAYKIQPDVFAVQGYDSAQLLAAGLSKAPAGAFDKE
                     AVMNAMSAATIDSPRGAFTLSKANNPVQDIYLRKAEGSQNKVIGVAAAKLADPARGCK
                     LMK"
     gene            13739..14605
                     /locus_tag="P5537_06695"
     CDS             13739..14605
                     /locus_tag="P5537_06695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HRV77768.1"
                     /translation="MDFTSFLIQILNALQYGLLLFLVASGLTLVFGIMGIINLAHGSF
                     YMIGAYLAFALSSLTGNLMLAIVLGIPLAFGFGALLERLLFVHLYKRDHLQQVLLTYG
                     LILIFEELRSLTVGDDVHGVAIPELFSASIALSENLSYPVYRLVISVVCIALAAGLWW
                     LMQRTRLGMMIRAGSFNREMVQSLGVNIDMLYRTVFALGVALAALAGMLAAPISSVYP
                     GMGGNVLIISFVVVVIGGIGSVWGALVAALLVGFADTFGTVLMPDLAGLAVYLLMAVV
                     LLWRPEGIFRKG"
     gene            14610..15578
                     /locus_tag="P5537_06700"
     CDS             14610..15578
                     /locus_tag="P5537_06700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004266032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HRV77769.1"
                     /translation="MNSGVVTLFKLAVLAGLMLFPAIGSSFYVELVAKILVMAIFAMS
                     LALLVGFTGLVSLGHAAYFGIAAYTVALIAPEYEAANLWFVLAASVLAAGAAAFFVGL
                     FVLRTKGIYFIMVTLAFAQMAYYIFHDTALGRSSDGIYLNVKPDASLFGWTPFSLDDP
                     AQLYYFILAAMAAVFVLLSFVLRSPFGRVLAGIHSNEHRMKSLGYATFRYKLAAFTLA
                     GALAGVAGFLYAVLFGFVTPEYLSWHQSGNVLLMVILGGLGSLAGAVAGAFAFIGLQE
                     MFSDWTKHWQLLMGLVIVAAVLFMPTGLAGLPRRIFRTVNWGEDDE"
     gene            15571..16326
                     /locus_tag="P5537_06705"
     CDS             15571..16326
                     /locus_tag="P5537_06705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV77770.1"
                     /translation="MSEAMLVADRLTRHFGGLTANLEVCITLERGKLHALLGPNGAGK
                     STCINMLSGDLPPSAGRILLEGQDVTGLDSAERSHRGIGRSYQRTNIFPQFTVLENCR
                     LAAQSRRPRPWRIFTDAMKTRDTVERARAAIVEAGLGGREQRKAGLLSHGEQRQLEIA
                     MVLATDARVLLLDEPLAGMGSEESAQMVELLRELKQNRAILLVEHDMDAVFAVADTIT
                     VMVEGSVLESGPPEQIRNSEEVQAAYLGEEEHG"
     gene            16319..17032
                     /locus_tag="P5537_06710"
     CDS             16319..17032
                     /locus_tag="P5537_06710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011288496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV77771.1"
                     /translation="MAEMLLEARDLHTYYGSSHILHGVSFSIRKGEALGLMGRNGMGK
                     TTLLRTMLGLVRPRHGTVRVNGDDMTRAKPHRIALAGVAYVPEGRGIFPNLSVRENLV
                     MAARAGVDGQREWTFERVMETFPRLGERIDNGGGQLSGGEQQMLTIGRALMTNPDLLI
                     LDEATEGLAPLMVKEIWKVIRTIRDSGIATVVVDKNHSAVTALTNRSMILVKGEVVFD
                     GPSEQVRQDPALIRKHLGV"
     gene            complement(17108..17503)
                     /locus_tag="P5537_06715"
     CDS             complement(17108..17503)
                     /locus_tag="P5537_06715"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004360773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HRV77772.1"
                     /translation="MQILQPAGWKRPKGYANGVVASGRMLFVAGQVGWDADEVFRSED
                     LVEQIRQALRNVLAVLDAGGARSTDIVRMTWYLANTAEYNARLGEIGAVYRDLVGHHY
                     PAMSAVQVAGFVEDGAKVEIEVTAVLADD"
     gene            17796..19979
                     /locus_tag="P5537_06720"
     CDS             17796..19979
                     /locus_tag="P5537_06720"
                     /EC_number="2.3.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004474 - malate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006097 - glyoxylate cycle [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malate synthase G"
                     /protein_id="HRV77773.1"
                     /translation="MTERVSCQRLQVAANLKRFIEEEALPGSGVDAAAFWSGFDVLVH
                     DLAPKNASLLAERDRIQAEVDAWHRAHPGPIADMAAYKAFLSSIGYLLPVPAGAKATT
                     TNVDDELAVQAGPQLVVPVMNARYALNAANARWGSLYDALYGTDAIPQKDGAELTKGY
                     NPARGAKVIAFGRSVLDQAAPLAGASHADAAGYAVEGGKLVVKLQNGSTTGLQQAEKF
                     VGFQGEAAAPSAVLLKNNGLHIEVQIDRNGAIGKTDAAGVNDLLMEAALSTIMDCEDS
                     VAAVDADDKVVVYRNWLGLMNGTLEDTFEKGGKPMTRRLNADREYTGADGKPVKLHGR
                     ALLFVRNVGHLMTNPAILWGEGKEIPEGVMDAVVTTLIAKRDLERRGNSRKGSIYIVK
                     PKMHGPAEIAFADELFTRVEQLLGLPGNTVKLGIMDEERRTSVNLRACIAAAPARVAF
                     INTGFLDRTGDEMHTSMEAGPMMRKGDIKNSKWIAAYERRNVLIGLAAGLRGRAQIGK
                     GMWAMPDLMAAMLEQKIGHPKSGANTAWVPSPTAATLHALHYHQVSVAAVQQDIEKLD
                     LDKEAEVLLDDLLTIPVVAKAEWSATERQQELDNNCQGILGYVVRWVEQGVGCSKVPD
                     INDIGLMEDRATLRISSQHIANWLRHGVVPAEQVEATLKRMAAVVDGQNAGDPLYRPM
                     APNFDDSVAYAAARALIFEGCAQPSGYTEPLLHRYRQQFKAKIGA"
     assembly_gap    20134..20233
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(20613..21422)
                     /locus_tag="P5537_06725"
     CDS             complement(20613..21422)
                     /locus_tag="P5537_06725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004333566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamD"
                     /protein_id="HRV77774.1"
                     /translation="MARFTPGSLTAKAALIGALLLGGCGLLPEQVDETAGWNAQKLYS
                     EAKASMSEGGYERAVTLFEKLEARYPYGRFAQQAQLEVAYAYYKQGEQALALAAADRF
                     IKLHPNHPNVDYAYYLKGLVNFNEDLGLLAGLSRQDLSERDPKGAREAFDSFRELVER
                     FPASRYAEDSRARMQYLINSLASHEVHVSRYYYNRGAYVAAINRAQTAVSNFPQAPAI
                     EEALFLMVMSYDKLGMAQLRDDADRVMRKNFPDSVYFRGGPEDDRPWWQLW"
     gene            21436..22431
                     /gene="rluD"
                     /locus_tag="P5537_06730"
     CDS             21436..22431
                     /gene="rluD"
                     /locus_tag="P5537_06730"
                     /EC_number="5.4.99.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004266016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(1911/1915/1917) synthase
                     RluD"
                     /protein_id="HRV77775.1"
                     /translation="MNERADYIPAVLPSDVLSDLPADELEACETLTIPAELGGLRLDQ
                     ALARLFPQHSRSRLQGWLKAGWIRVDGGSPDARRKVCGGECVEIDAPPPPELAAELPE
                     DIPLAVVYEDEDLLVIDKPVGLVVHPGSGNWSGTLLNALLHRNPGLAGLPRAGIVHRL
                     DKDTSGLMVVAKTLAAQTELVRQLQARTVGRHYRALVQGELSAGGTVDAPIGRHPTQR
                     TRMAVVGNGRPAVTHYRVTERFSRATLVECRLETGRTHQIRVHMAHIGHPLVGDPLYG
                     ARRCGDARLDGFPRQALHAFRLGLVHPRSGEAMRWEVPLATDFATLLDELRGAPR"
     gene            22428..23213
                     /gene="pgeF"
                     /locus_tag="P5537_06735"
     CDS             22428..23213
                     /gene="pgeF"
                     /locus_tag="P5537_06735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HRV77776.1"
                     /translation="MSLPPHGYQPFAPGLLRPEWHLPPGVHAMVSTREGGASLAPWAS
                     FNLGSHVGDDARAVAANRARLCAATGAEPVWLEQVHGCAVADADCTAGVPAADAAVAR
                     ATGRACAVMTADCLPVLFCDADASVVAAAHAGWRGLAAGVLERTVERMGVAPGRVRAW
                     LGPAIGPAAFEVGDEVRAAFVGADPGAAAAFVPGVAPGKWLADLFMLARRRLVAAGVG
                     RIDGGGVCTVADPGHFYSYRRDGTTGRFASLIWLEEGRRGGIT"
     gene            complement(23263..23484)
                     /locus_tag="P5537_06740"
     CDS             complement(23263..23484)
                     /locus_tag="P5537_06740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004360781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77777.1"
                     /translation="MYLIPIAWLYVVILVAAAEDTIVAAVLTFVFWGLAPLALFLWLF
                     GTPARRRRRLEQEREALERNDRAETDADQ"
     gene            23592..25337
                     /gene="phaC"
                     /locus_tag="P5537_06745"
     CDS             23592..25337
                     /gene="phaC"
                     /locus_tag="P5537_06745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004360783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0042619 - poly-hydroxybutyrate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I poly(R)-hydroxyalkanoic acid synthase"
                     /protein_id="HRV77778.1"
                     /translation="MSDSTGKQVPPGMQAILAAGQAMAQGFFDALARQHVAMQDSSGV
                     AAQKLPMPETEVMASLHQAFAEKHAELWSSMLARTPGEAGPAVVQPEPGDKRFAAPEW
                     SESPVFDYMRQAYLLNAGFLRQMADAMPIADGRAKARMQFLTRQYIDALSPSNFAATN
                     PEFIKTAVETKGESIARGIQNLLGDLEKGRISMTDDAAFEIGRNLALTPGSVVYENEL
                     MQLIQYAPLTEKVAQAPLLIVPPCINKFYIMDLQPENSLVRFVVEQGFTVFLVSWKNP
                     RPDTGGHYTWDDYLDKGPLAALEVVRSITRVKKPNVLGFCVGGTILTSALAVARARGE
                     EPVASLTLMTTLLDFSDAGELGCLVDEASVTAREAAIGKGGVLKGQELANVFSFLRAN
                     DLVWQYVVGNYLKGNKPVAFDLLYWNSDSTNLPGPFLTWYLRNMYLENNLRVPGKLRM
                     LGQKVDLGKVDVPAYLMAAREDHIVPWKSAYLARNVLGGETTFVLGASGHIAGAINPA
                     SKNRRSYWTADVRPADPDEWFDGAAEHKGSWWLHWAEWLRGHGGKEVAARGRLGSTKY
                     EPIEPAPGRYVKERS"
     gene            25453..26193
                     /gene="phbB"
                     /locus_tag="P5537_06750"
     CDS             25453..26193
                     /gene="phbB"
                     /locus_tag="P5537_06750"
                     /EC_number="1.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011764756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018454 - acetoacetyl-CoA reductase
                     activity [Evidence IEA];
                     GO_process: GO:0042619 - poly-hydroxybutyrate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetoacetyl-CoA reductase"
                     /protein_id="HRV77779.1"
                     /translation="MARVALVTGGMGGLGEAICIKLAALGYKVVTTHSPSNTKAQEWL
                     QTMNNMGYGFKAYPCDVADFDSCKACVEQVTKEVGAVDVLVNNAGITRDMTFKKMTKA
                     DWDAVISTNLDSAFNMTKQVMDGMVERKWGRVINVSSVNGQKGAFGQTNYAAAKAGMH
                     GFTKALALEVARNGVTVNTISPGYIGTKMVMAIPQEILDSKILPQIPVSRLGKPEEIA
                     GLVAYLSSDEAAFVTGANISINGGQHMF"
     gene            26434..27174
                     /locus_tag="P5537_06755"
     CDS             26434..27174
                     /locus_tag="P5537_06755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011764757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP reductase"
                     /protein_id="HRV77780.1"
                     /translation="MSQKIALVTGAMGGLGTAICQSLSKDGFKVVANCLPNFEQKDAW
                     LSAQRDLGFDFAAAEGDVSNYESCAAMVAKIEADIGPIDVLVNNAGITRDKFFPKMEK
                     GQWDAVINTNLNSLFNVTHHVSSKMAERGWGRIINISSVNGVKGQAGQTNYSTAKAGV
                     LGFTKALAAELATKGVTVNAIAPGYIGTDMVMAIREDIRQGIIDTVPMKRLGRPDEIG
                     DLCAYLASDKAAYITGATININGGLHMC"
     gene            27305..27886
                     /gene="phaR"
                     /locus_tag="P5537_06760"
     CDS             27305..27886
                     /gene="phaR"
                     /locus_tag="P5537_06760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004266001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyhydroxyalkanoate synthesis repressor PhaR"
                     /protein_id="HRV77781.1"
                     /translation="MPEQQRLIKKYPNRRLYDTRTSSYITLADVKDLVLNHEHFQVVD
                     AKTGEDLTRSILLQIILEEEAGGAPMFTSDLLAHMIRFYGNAMQGMMGKYLESNIKAF
                     TEMQVKLQDQARAIYGENSPVGQDLWAQFLNFQGPALQSMMGAYVDQSKKMFEQMQTQ
                     LESQTRNMFTGFQFPGYVRPEDEPAAPKGDGKK"
     gene            27941..29272
                     /gene="rimO"
                     /locus_tag="P5537_06765"
     CDS             27941..29272
                     /gene="rimO"
                     /locus_tag="P5537_06765"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008172 - S-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016782 - transferase activity,
                     transferring sulphur-containing groups [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0018339 -
                     peptidyl-L-beta-methylthioaspartic acid biosynthetic
                     process from peptidyl-aspartic acid [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HRV77782.1"
                     /translation="MTTFKTPDLPRVGFVSLGCPKATVDSEHILTRLRAEGYSISGSY
                     DDADLVVVNTCGFIDAAVEESLDAIGEALAENGKVIVTGCLGAKDDVILAAHPQVLAV
                     TGPDATEEVMHAVHRHLPKPHDPFTDLVPPQGIRLTPQHYAYLKISEGCNHRCSFCII
                     PSMRGDLVSRPIHEVMREAEALADAGVKELLVISQDTSAYGVDVKYRTGFWGGRPVKT
                     RLLDLAKALGELGIWIRMHYVYPYPSVDDLIPLMAEGKILPYLDVPFQHASPRILKAM
                     KRPANAENVLERVRKWRSICPELTIRSTFITGFPGETEEDFEMLLNFLEEAQLDRVGA
                     FAYSPVEGATANELPGAVPDEVREERRARLMDFQEDISTQRLEAKIDREMTVLVDEVD
                     EEGALARSPGDAPEIDGLVIIPEGDGLAPGDFVRVRITDCDVHDLYAERIE"
     gene            29303..30277
                     /gene="rssA"
                     /locus_tag="P5537_06770"
     CDS             29303..30277
                     /gene="rssA"
                     /locus_tag="P5537_06770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004265997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004622 - lysophospholipase activity
                     [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase RssA"
                     /protein_id="HRV77783.1"
                     /translation="MVSGAGAVGLACAEPSTAGPVIGLALGSGAARGWAHLGVLQELA
                     REGVVPQIITGCSIGAFVGAAAASGDLAKLVRWAETLKWQDVVSLLDVSLRGGLIKGQ
                     KLIDFFERNFVDRDFTELDQRFACVATELSTGREIWLHEGSVSAAVRASIALPGLMTP
                     VLHQGRMLVDGGLVNPVPVSLCRAMGADVVIAVDLGSDMVGRASRRSAVAPAPVEETE
                     AGWTERLLARFGFASDEEPGAPARPLAADDNLPSLVSVISSSINIMQVRIARSRLAGE
                     PADLLVSPRVSQLGLMDYHRADEAIAEGVAAVARVRPLLRELLGGTNE"
     gene            30285..31694
                     /locus_tag="P5537_06775"
     CDS             30285..31694
                     /locus_tag="P5537_06775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HRV77784.1"
                     /translation="MSDELNARLRTIVGAANVLEAEADMAPFLSDWRGRYHGRARAVV
                     RPRDTAEVAAVVAACAQAGVAMVPQGGNTGLCGGATPLVDGAAVVISLARMNRIRALD
                     ADNDTLTVEAGCTLAAVQEAAQAAGRLFPLSLASEGSCLIGGNLSTNAGGVQVLRYGN
                     TRELVLGLEVVLPDGRVWDGLRGLRKDNTGYDLKQLFIGAEGTLGIVTAAVLKLFPAI
                     RSRAMAWVAVPDPRAAVRLLGMLRAVCGERVSAFEIVGRTALGLVLQHIPGARDPLAG
                     APAWSVLVELSDPDVDAPLDAQLQAVLGEACAQGLAADAAVAASAAQAQALWALREDI
                     SEAQRIEGVSIKHDVSVPVSRIPEFLERAGAALAARWPDVRVVAFGHIGDGNLHYNLS
                     KPAADDNAAFIARTAEVNRIVHDLVCELGGSISAEHGLGQLKREEVLRYKPALEMELM
                     RRVKQAFDPAGLMNPGKVL"
     gene            31758..31833
                     /locus_tag="P5537_06780"
     tRNA            31758..31833
                     /locus_tag="P5537_06780"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:31791..31793,aa:Ala,seq:ggc)
     gene            31848..31923
                     /locus_tag="P5537_06785"
     tRNA            31848..31923
                     /locus_tag="P5537_06785"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:31882..31884,aa:Glu,seq:ttc)
     gene            31983..32059
                     /locus_tag="P5537_06790"
     tRNA            31983..32059
                     /locus_tag="P5537_06790"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:32017..32019,aa:Asp,seq:gtc)
BASE COUNT         5000 a        10612 c        11357 g         5143 t
ORIGIN      
        1 tggcagctcg tcgggctcat aacccgaagg tcgcaggttc aaatcctgcc cccgcaacca
       61 aacaaagcaa aaagccaatc acctcaaggt ggttggcttt ttgcttttgt gccttgagcg
      121 tgccgccggc gggccaatgt ccgccggcgg cacgctcaag gagccgcgag acctgatcgg
      181 gtcgctgccg tgccctgcgc ggccaccggg aaccacagcg tcacgcaggt tccgatgtcc
      241 ggcgtgctct cgaggctcac gctgccgcca tgcagcttca tgatctcctt caccaggggc
      301 aggcccaggc cggtgccggg gatgtggccg gagcggtcgc tgcggtagaa gcgctcgaag
      361 gcgtgggtgg cgtccgcagc gctcatgccg atgccgtgat cgcgcaccga gatgccgatc
      421 aggccgaggc catccgggtg ttcggccacc acctccacct cgatgtcgcc gccgtgcggc
      481 gagaacttgc gcgcgttcga cagcaggttg agcactgtct gctggaattt cgcgcggtcg
      541 gcgcggatcg agggaaggtc cggtggaatg cgggcgacca ggcgatggct ctcggcgggc
      601 accaggaagc cggacagcgc ctcctcgagc agtggcccgg ccggcagcgt ctcgaactgg
      661 aagctccggg cgcggcgtgc ctcgatgcgg gcgaggtcga gcaggtcgtt caggagtccg
      721 gtgaggcgct gggcctgggt gttgatcgtg ccgagcagtt cgcgcgtctt ctcggcactg
      781 tagctgcgca tcatcaggag ctcggagaag cccatgatgc tcgccatcgg cgtgcgcagc
      841 tcgtgcgcag cggtggcgag gaagtcgctc ttcatgcggt cgagttcgac ctcacgggtg
      901 acgttgcgga agtagatcac ctgcgaggtg gcgtcggtgc cgcactcgcg gaagctctgg
      961 tgcaatgtgc agcgccgcgg atggacgaga tggatgaggc cctcccgggc aaagtccagc
     1021 ggcgcgttgg tgggcgagag gtcgagctcg tcgtcggcga ggggggtgaa gggctgcgcg
     1081 gggtcggcga gctgggcgag gcgctggcgg aattcggcta cggtggagcc gatcagtgcg
     1141 ccggccgcgg gggcgaagag ggtctcggcg gctgcgttgg cgaagctgac ggtgcccgcg
     1201 ttgtcgaagc acaccacggc gtcggggttg agggtgaaga tcacgtcgag ccgcgacaac
     1261 cagtcgatca gctgatcttc cgactgccgg cgtgcggtca cgtcggcctg cacgccgacg
     1321 tagtgcgtga cctcgtccga ggccgggtcg accaccgggg cgaccgcgag ctgattccag
     1381 aagaagctgc cgtccttgcg gtagttgcgc agcgtgactt cgcaggggcg ccccgcgctg
     1441 atcgcgcgcc gcagcatcgc cacctcgggt tggtcgtggt cgctgccacg cagaaagcgg
     1501 cagttgcgac cgatcgcctc gctgcgcgca tagccggtga tgtgctcgaa ggcgcgattg
     1561 acgtagatgg tcgggcagtc gggctggcgc atgtcgatga tcgagatgcc gctgccgacg
     1621 gcctcgagcg cacggtcgcg gatcgcgatc tccatcgcgg cctcgcgtcg ctccgtgatg
     1681 tcggtgagga tgccggcaaa gccggtgatg cgttcctcgt cgcgcagggt gttgagcttc
     1741 accgagagcc agcgcgttgc tccgtggcgg cagcgcacgc ggcattcgaa ctcgtggttt
     1801 tcgagctcgc cctggcgcag tgccgtcagt gcctgcaggt ttcgccgcag gtcgtcgggg
     1861 tgcatgaagt cggtgtacgc gtggcccagg ctgtcttcga tgaggtggcc ggtgatcttc
     1921 tcccaagcct ggttgaggaa gttcaggcgg ccgtccaggc ctacctccac gacgacttcg
     1981 ccgaggctct ccaggagtct gcggtgtgcg cgatcggctc gcaggcgttc gctcacgtcg
     2041 ctcaccagca cgatggcgtg agtctccgta cccgtctcgg cgtcgatgac tcgggaagtg
     2101 gacagctcca tgaagacctg caccccgtcc gcacgccgcc atgcgagttc cgccggcctg
     2161 tccggtgcgg gaccgggctc cttgccgaag agcagtgcgg gccaccgcgc gccgaggatc
     2221 gcgtcggcgg cgaggccggt catctcgagt agcgcagggt tggcatactg cacgcgcgcc
     2281 tcgtcggcgg gccggtgtgc cacgatcagg acgccggtgg tgctggaggc gagtgcgcgc
     2341 tccttgaggc gacgttcggc ctcggcgcgc tcgacctggc gagtgcgggc ctccagggtc
     2401 gcggacaggc gctgctgcgt gtcgcgcagg ctggcgatca tgcgatagac cgtgttggcg
     2461 aggacctcga agcggtcggc gtcgtcgacg ccggctcgcg gtggcggcag ggcgtcgaga
     2521 tcgccggcct ccacccgggc tgcggtgagt tcgagctcgg ccagtggcgc accgatatcg
     2581 tgcgcgatgc ggcgaatcag cagcagggcc agcatcagca cgatggtgcc gatcaccacc
     2641 atccctgcca gcaggccgcg gaccggacgc agggcgagct cgcggtcgac gacgacctcg
     2701 atcgccagcg gcaggccatg gtggccggtg agccgggtga ggtatcgcag ttcccgcccc
     2761 gtgtccgcga gcccggcctg cgccgtcggc gtgccggcga ggtcgcgcag ccgcagggta
     2821 tgtccgcgcg ccacgccggc ggtgctggtg tcgaaagtcc tggccagttc gagttcggcg
     2881 ccgagtgcac cttctggatt gccggtgggt aggtggatga ccggcgccgc gatgcgcagg
     2941 cggagctgct cgctgccatg tgcgagcgcg aactgtgccg tcgagcgttc gacggcttcc
     3001 tgacgcagcg cgctggtgct ggcgaagtcc gcggcggaga tgtcctcgcg cgcacagcct
     3061 tgttcgagca ccttgccgcg gaaatcggcg aggaagaggg ccgcaagctc aggcgtggcc
     3121 cgacagaggt cgtgcagggt ggggcggatg tactgggcgc ggccggccgg atcggaaagc
     3181 gcgtggctga agatcgtctg gcgcgaggcg tcgaggatct tgccgatatc ggcctcgagc
     3241 cgcgcctcga agcgcagccg tgcctcggag gccgtggcct cgagttcgta gcccagcttt
     3301 tccagcatca gggcatgcag tgcagcccac gacaccagca gggcgggcat caggacgatc
     3361 gtcgtcagtg tggtggcgag gaacgagatg cgggtcgtga gactggcgcg gcgccagcgg
     3421 cgcgagcggt cgagcaatgg cagaggcatc ctggtcggtc tctccgttca gtgcggctgc
     3481 agcagaccgg tgctgtcgaa gcggcaaagc aacacctcgt ccttgcccag gccctcgtgc
     3541 cgcgcgggcg tgaaggcggg agcgtgacgg cgtaccacgc cctcgtgcgc gggcaggcgc
     3601 tcgagcgcct cccggatggc cgggcggtgt gtgccgcccg tttgatcgac cgccatcgcg
     3661 agcaggcgga cgaggtcgta ggccgggccg attgcggtct gcgaggggac agcaagcggc
     3721 gaatcggtgc cgaagtgctg catggcgcgg cgggcaaggc gggcgccatc ctcaccgcgg
     3781 gcgcgtgcga agctgaacga ttgcgccaca tcgagctgga ccttgtgcag agcctccccg
     3841 cacaaccggg ggaagcgccc gccgctgatg ccccagtggc tgaagagcgg tcgcagatcc
     3901 cgggtcgcca tggaggccat cgccttgacg agggtcgcac cctcgggttc gttggcgacc
     3961 agcaggatcg cctccgcgcc gatctcgagc agcgtgcggt agctgtgcgg gatcgagtcg
     4021 tgagcccccc agcggtgcca ctcgatgccg acgatctcga ggcgatcgcg agtccgggcg
     4081 ccgacatggc gctcggcggc gtactggcag ctccttcccc acgcggtctg gggaacgagg
     4141 aggccgatgc ggcgcagctt gcggcgttcg atctcgccga gcagggcctc gatcgcgagc
     4201 gtgtccgaca ggccgaggcg gaaggcgtag ttgggctccc ggccgttgtc gatgatcgcg
     4261 tcggcggcag cccagggggc gagcaagggc aggcgcaggg cgtgcagcgt cgggacctgc
     4321 tcgagcacca cgggcgaaaa cttcccgcac aggaaaccga cgacatcggg ctgggcgccc
     4381 aggtgctcga tgttggccac gccacgggcg gggacgctgc ggttgtccgt gatcaccagc
     4441 tgcagggggc gtccgccgag cactccaccg tgggcgttga ggtcttcgat cgcggctcgg
     4501 gcgccgaaga ggatggcgtc gtcggcggtg ctgttggggt ccatgaactc cgcatccacc
     4561 ccgatcagca ctggtgccgc gcggccgaag gcccgcccgg gcagtgcgca ggcgagcagg
     4621 ctggcggtgc aggcgtgcag gaagtcacgg cggcccccgg gcgcaaggct catcggcccg
     4681 tctccgcagc ggcgaggcgc tcgacggtct cgatcagctg aagcgggctg aagggcttgg
     4741 tcaggtaggc gttgcagccg gcccgtcggc cggcctcgag gtcggtctgc tggctgcgtg
     4801 cggtcagcat caccaccggg atgtgcgcga tctcggggtc ggcgcggatg cgctcgcaga
     4861 cctggatgcc gtcgagctgg ccgggcatca tcacgtcgag caacacgatg tgagggcgca
     4921 gggccttgac catgcgcagg ccggtgtcgc cgttgtcggc ttcgtgcacc tcgaagccgt
     4981 cgtaatccat cgtcatgcag atcagcttgc ggatctcggg ctggtcctcg acgacgagga
     5041 ggatcgtgtt catgtcgtgt gttcctgcgg ggtgtgtggt cggaagctgc gggtagtcgt
     5101 gctgccgccc catcgggggc ggcgcttcga ttcgtgagac ggtctcagct gagcgcggcg
     5161 agtgttcgcc accaatgtgg cggcgggctg ccggctccgg cccgtgcggc atggagtgcg
     5221 gcccgtttgc gcagctgcgg cagttgcggg cggatccggt gcatcgcggc tacgaccgca
     5281 gggtcgaact gcatgcctgc ggcgagatcg agcagcgcga agatcgcgcc ttcgtcgagc
     5341 gcatcgcggt agctcgcacg cgagccgagc gcatcgacga agtcggcgac cgcgacgatc
     5401 cgccccgaga gcgggatgtt gctgccctcg cggccggcgg gatagccgct gccgtcccat
     5461 ttctcgtgat ggttgagcgc gacctcggcc gccagcgcgt gcagcggatc gctcgccacg
     5521 cccaggatgc gcgcgccgtc gagcggatgg cgccggatcg ctgcccactc ctgcggatcc
     5581 aggctgcctg gtttcgcgag gatggcctcg gggacggcaa ggttgccgat gtcgtgtacg
     5641 cgcgcggcgt cggacagatc gtcgcaccac gccagggggg agccgagcgc gtggccgatc
     5701 agcgcggcgg tcgcgccgac gcgcaggccg tgctcgagcg cttcacggcg cccgcgcgcg
     5761 gcggcaagcg cgagccgggc gatcgactcg cgctgcaagc ggcgcatcgc ctcgcgctcg
     5821 cggtcgcgtt gcgtgaccac ggtgcgcagg tcgtgcaaca cccggtacag ctggcggtag
     5881 gggtcgcccg ggcgcctcgc gggtgcggac tcgtcgcagc tggccgcggg ggcgcggggg
     5941 tttgcggcga tgccggggag gctgtcgtca tcgagttcga tcggctcctg gaggagcagc
     6001 gtgctcgaag ccgcggcggg gtgtgcgctg gtgttcatcg ggcaacgtcc tcgccggccg
     6061 gacgggagcg gcgggtcatc aggcgggcga gatcgctcgc gtagcgctgg gcctgggcga
     6121 tgtcggtctc gaccgtggtg aacgggctgg cgctggtggg cagctcgatc gcggcggtga
     6181 cgaagccgtc gagttcctgg tcgagcgcga gtcggccgtg gtgcatctcg acgatccggc
     6241 gtgccagcgg caggcccagg ccgagtccgg gcgcgcgggc ggtcgcggcg gcgctgcgca
     6301 tcagcggctg catcaggcgc gcgcgcagca atggcgagcg caggccccgg ccgcggttgc
     6361 gcagggtgat gcgtacgaat gcggccgagg cgctgagcgt caggctgatg tcggtgccgt
     6421 tgtcggagtg ttctagggcg ttgtcgatgc acgcgtcgaa ggccaggccg agccagtggg
     6481 cgctgccgta gatcaccgga aagctgccgg tcgccggcga gaccagattc aggcgctggc
     6541 ctcgtgcatg tgccgccggc tcgtggcgtg cgagcaggcg cggcagccag tcggcgagtt
     6601 cgatgcgatc gtcggcctgg agcgggcggc cgctgccgag ctggacgagg tggaccaggt
     6661 cgagcagttg ctgcatcagc agctggcccc gctcgatatc gcgggcgcgg ggggctgtct
     6721 cggtcgtcgc ggcggcgggc agtcgtgccg cttcatcgag cagttcgccg aagtcttcag
     6781 caaagcgctg aagcggctcg agcatgctgt gctcgatcag cgcgcagagg ttgtcgatcg
     6841 tggtctggta gacgctcgcc tcggtcatgt tccgcaatac cagcaccagg tccttgcccg
     6901 cagggctgcg gacgatatgg cctgccagct ggtccggcgc ggcgacctgg gtcggatgca
     6961 cgatctcgct ctcgaaggcg tgcggcagcg gaatgtggcc cgtcagggcc tggtcgagca
     7021 cggcggcgat ggtggcgtgc ggcacgggtt cgcccagacg taccggcagc agcgccagca
     7081 tcccctcgtt tgcgaagcgc acctttccgt ccggggcgat gatcgcgagg ctgtcggaga
     7141 ggcggttgaa caggatctgg atcgcagggt tcactggaaa tggtttaatc aacaaaaaag
     7201 tgataaaaat attataaaag ctataataaa ttgagcgtgc gatccgtcac gctccggtgc
     7261 gcgtcattga actagcatcg cggcgcatca aatgacgaga aggtctggag cggagcttgg
     7321 aacgagcgga ggggtgggcg ggacaggtgc gaggggcaga cgatgcgaca gcgcacgagt
     7381 cgtccggtgc agatgctgcg cgctggccgc tggtgctgat cgtcgtgctc gcgttcacgc
     7441 tggtcgcatc ggtgtgggcc gcggtgctgt tcaaggtggc cgcggaggag cgtgccgagc
     7501 ttgccgcgat cgaacgccgc acgaccaatc tcgcgcgtgt cttcgaggag cacaccgtgc
     7561 gcacgctcgc cagcgtcgac caggcgctgc tgttcgtgaa gttccagtac gagaaggtag
     7621 gcgccgcgct cgacatcgcc tcggcggtgg agcagggcat gatcgtcagc accctcttca
     7681 accaggtcgg ggtgatcgac gcgcagggca tctacagcct gtccaacctg cccggcttca
     7741 agcgtgtgga cctctccgat cgcgagcatt tccgcgtcca tgtcgacgcg gactcgcgta
     7801 acttcttcgt cagcaagccg gtgctcgggc gcgcgagcgg caagtggtcg gtgcagctca
     7861 cccgccgcat caaccgcgcc gacggcagct tcggcggggt ggcggtgatc tcgctcgatc
     7921 ccttctactt caccaccttc tacagtgacc tcgatctcgg tcgccacggc gtggtgaccc
     7981 tggtcgggct ggacggcatc gtgcgcgcca ggcgggcagg cgacgttacc gacgtggggc
     8041 aggacatccg caggggagcc ttgtttgccg aactcgcgaa ggcaccgcag gggcactacc
     8101 actccagcag cgcgatcgat ggccgcgtgc gcatcgtcag ttatcgttcc ctgcccggtc
     8161 tgccgctggt cgttctggta ggcgtcgatg ccgacgaggc gatgagcgac tttcgcgtgc
     8221 gccgcggcgg ctacctcgcc ttcgccgccg gcatgagcct ggtcatcgcc gctttctgcg
     8281 cgctctcgct gtggctgctg cagcgtcagc gacgcatctc gatgcggcta cgcgagatga
     8341 agccgcgcgc ggagtcggcg aaccggctca agtccgagtt cctcgcctcg gtgtcgcacg
     8401 agctgcgcac cccgctcaac ggcgtgatcg gctattccga actgctgatg gagctggcgc
     8461 aggacgagga gcagcgcagc tacgccaggg tgatcctcga cagctccggg catctgctcg
     8521 aactgctcaa ctccatcctc gacctcgcgc gggtggaggc ggggcagatg gcgatccggc
     8581 tggcgcccga ggatgtggcc gggatggtcg gccaggtgtg cgccaactac cggccggtgg
     8641 cgcaggccaa gggcgtgacg ctggcgtgcg aggcgcccgc cggcgtgatg ctggagtgcg
     8701 atcgcacgcg cctggtgcag gtgctgaaca atctggtgca caacgcgctc aaatttaccg
     8761 acagcgggcg ggttagcgtg cacgcgcggc tgacgccgac gcattgcgtg ttcgaggtgg
     8821 ccgacacggg ctgcggcatc gcgcccgacc aactcgaggc gatcttcgag cgcttccgcc
     8881 aggtgcatga tttcgaaacg cgtgcccatg gtggcaccgg gctcgggctt gcgctatgca
     8941 aggagctcgc ggaactgatg ggtggcggga tcgaggtgcg ctcgacaccg ggcgagggta
     9001 gcgtgttcag cgtcaggctg ccgcgttcgc cgaaggggac ggaatgatga aagtgctggt
     9061 cgtggatgac aacccgatca atcgcctgtt gccgatcgcc tggctcaagc gcctgggttg
     9121 cgagaccgag gagagcgccg gtggcaccga tgccctcgac aagctcgcga cgggcggttt
     9181 cgacgtcgtg ctgctcgacc tcagcatgcc ggagatgtcg gggacggaga tctgtcgcag
     9241 ggcgcgggcg atgccggcag gcgggaagat ccgcatcatc gcctacaccg cgcacgcggc
     9301 gccggaggcc ttcgagtcct tccgctcggc cggcttcgac gacgtgctgg tcaagccggt
     9361 tacgcgcgat gcgctgctcg gggttttcgg cgggctcgaa ggattcgagg acatgcgcac
     9421 gcccggagcc gcgggctgaa gcggtagcgc atccggttcg ggcgtggcct ccgcctgcct
     9481 caggcgccgc gatcgacgac ggctgcgcgc agcgcgcgga agctttcgtc ctcgccctga
     9541 cccgaggtgt cgaccacgtg gtcggcacgc atgtactgcg cttcgcgcgc ggcgaggatg
     9601 cggcgcaggt cttccatcgc ctcggcgctg ccggccatgg ggcgcaggtc gccctgcgcg
     9661 ctcacgcgct gcatgtgttc ctcgggcgag gcacgcagcc agatggtgag gcagcgcgac
     9721 agcagcaggt cgtaggtctc ggtctgcgac acgatgccgc cgcctgtggc cagcacggtg
     9781 cgctcgccgc tgtcgagcgc gcgccgcagg cagcgctgtt cgatgcggcg gtaacccgac
     9841 tggccgtaga gggcgaagat ctcgcccatg ggcatgccgg tctcgcgctc gatctccgcg
     9901 tcgagctcga cgaatcggaa gccgagctcg gccgccagcc tgcggcccag cgtggtcttg
     9961 ccggcgccgc gcagcccgat cagggcgatg cggttgcgcc gtgcggcctc ttcctggccg
    10021 tagtcgcgca tcagcctgaa gatcacgtcc tccagccggt gccgcggcag ctgctcgagg
    10081 atgcgccgca ccaggcgctg ctccaccgac tcctcgacac ccaggttcag cagctccggc
    10141 aggggcagcc ccagcgcgcc gccgatatgg cgcagcagca cgatcgagac gttgccctcg
    10201 cccgcctcga gatgggccag gtggcgctcc gaaacacccg cttctcgcgc gagctgcttg
    10261 cgcgtctgcc cgcgccggtc gcgcgtctcg cgcacgcgct tgccgagcgc gagcaggaac
    10321 tccccgtcgc tgcgcggatc gggccggatg ccgggttgtg cgaccgggac ggccgcggcg
    10381 gaagctgcaa gggtctgatg ttcgtcgttc atgacgggtg cgctgttgcg gattcgtgcg
    10441 tttatggtcc tgcaggcgat tggctgtcaa ccgggcggca tcggagggtc gcaggcccgc
    10501 tgcgggcgat gaagtgcagg ataggccata atgcaatata ttgcagttta gactatatct
    10561 aaactgctga atttacgggg gtttgctgtg gcgcagggtt gacactgctc tagatggggg
    10621 tattcttttg catgtctcgc ttaaagatgc actttagtgc acattgcccg gctggctcga
    10681 gctgcatcgt ggtcggtcgg ggcggcgatc gcgtcaagga tttcctgcat ctgtccgttc
    10741 cgcaagcaaa ccggaccgga cgatccggga tcaggatgga gacaggacga tgcacaccct
    10801 cagcaccgca gatcacggct gcacgccgcc ccggatcgag attccggacc cttacaacgc
    10861 ggccgacgac ctgctcgggc gcaacctggt cgccggacgg ggcggcaagg tcgcctacat
    10921 cgacgatgcc ggcgaataca cttacgacca gcttgccgcg cgcgccaacc gctgcggcaa
    10981 tgcgttgctc ggcaccctgg gcctggcgcg cggcgaccgc gtgctgatgt gcgtgctcga
    11041 ctgcatcgat ttccccgcga tgttcctcgg cgccatcaag gccggggtgg tgccgatcgc
    11101 ggtcaatacg ctgcttaccg aacgcgacta cgagtacatg ctgtccgaca gcggtgcgcg
    11161 cgtggcggtg gtgtcgcagg ccctgctggc caatttcgct gcgctgcccg ggcgcgtgcc
    11221 gacgctcgag cgcctggtcg tcgccggcgg cgacgacgac gacggcttgg aggcgctgct
    11281 ctccgcgcag tcggaccagc tcgatgccgc accgacgcgc gcgaccgatc cctgtttctg
    11341 gctctactcc tcgggctcga ccggcgcgcc caagggcacg gtacatatcc actccaacct
    11401 catccatacc gccgagctct acggccagga agtgctcggc atccgtgagc aggatgtggt
    11461 gttctcggcg gcgaagctgt tcttcgccta cggtctcggc aacggcctca ccttcccgct
    11521 ctcggtcggc gccaccgcgg tgctgatggc cgagcggccg acgccggacg cggttttcag
    11581 gcgcctgcgc gaacaccagc cggacatctt ctacggcgtg cccacgctct atgccggcat
    11641 gctcgcgcac accggctgtc cgaccgcggg cgagttgaag aatctgcgcg cctgcacctc
    11701 ggcgggcgag gcgctgcccg agggcgtggg gcggcgctgg aaggagcgcc tcggggtcga
    11761 catcctcgac ggcatcggct ccaccgagat gctgcacatc ttcctgtcca accgcgccgg
    11821 cgacgtgcag tacggtacca gcggcacgcc ggtgccgggc taccgcgtcc gcctggtcga
    11881 cgaggcgggt gaagaggtca ccgcggccga ggagccgggc gagctgcaga tctccgggcc
    11941 gagctccgcg gtgcagtact ggaaccagcc ggagaagagc cgcgcgacct tcctcgaggg
    12001 ctggacgcgc agcggcgaca agtactaccg caatcgcgac ggctactacg tctattccgg
    12061 ccgcagcgac gacatgctca aggtgagcgg catctacgtg tccccgatcg aggtcgagtc
    12121 cgcgctgatc gcccacgagg cggtgctcga ggccgcggtg gtcggcatcg aggacgagga
    12181 gcgcctgatc aagcccaagg ccttcgtcgt gctcaagccc ggcttcggtc ccggcgaggc
    12241 gatgcggcag gagctgcagg cgcacgtcaa gggcatgctc gccccctaca agtatccgcg
    12301 ctggatcgag ttcgtggagg atctgcccaa gaccgccacc ggcaagatcc agcgcttcaa
    12361 gctgcgcggc atctagcgct tcggcggcgc cggggggcgc cgctcgtgtt cacaccatca
    12421 aaaaagagga gacggacatg gtcggaaagg acaggaagct gcgtctcgca gtgagcgcgc
    12481 tcgggctcgg cctgggcatg ttgctggcgc agggcgcggc ggaggcggcg gacaaggtca
    12541 aggtggggct gatgctgccc tacaccggca cctatgcctc gctcggcaac gcgatcacca
    12601 acgggttcaa gcagtacgtg gcggagcagg gcggaaagct cggcggtcgc gaggtcgagt
    12661 acttcgtcgt cgatgacgag tccgatgcgg ccaaggcgac cgagaacgcc aacaagctgg
    12721 tcaagcgcga caacgtcgat gtgctggtcg gcacggtgca ctcgggcgtg gcgctggcga
    12781 tggccaaggt cgcgcgcgac tccaagacct tgttgatcat cccgaacgcc ggcgccgacg
    12841 agctcaccgg cccgctgtgc gcagcgaacg tgttccgcac ctcgttctcg gcctggcagc
    12901 ctgcccatgc gatgggcaag gtggtcgccg agcgcggcca caagaacgtg gtcacgctga
    12961 gctggaagta ttccttcggc gaacagtccg tggccggctt caaggaagcc ttcgagcagg
    13021 ccggcggcaa ggtggtgaag gaactctacc tgcccttccc gaacgtcgag ttccagccct
    13081 tcctgaccga gatcgccaat ctcaagccgg atgcggtgtt cgtcttcttc tccggcgcgg
    13141 gcgcggccaa gttcgtgaag gactacgagg cctccgggct gaaggcgaat cttccgctct
    13201 acgccccggg cttcctcacc gatggcacgc tggacgccat gggcggcgcg ggcgagggcc
    13261 tgctgaccac gctgcactac gccgacgggc tcgacaacgc gaaggagaag gccttccgca
    13321 gtggctacgt cgccgcctac aagatccagc ccgacgtctt cgcggtgcag ggctacgaca
    13381 gcgcccagct gctggcggcg ggcttgtcga aggccccggc cggcgccttc gacaaggagg
    13441 cggtcatgaa cgcgatgagc gccgccacca tcgacagccc gcgcggcgcc ttcaccttgt
    13501 ccaaggccaa caacccggtg caggacatct atctgcgcaa ggccgaaggc agccagaaca
    13561 aggtgatcgg cgtcgccgcg gccaagctcg ccgatccggc gcgcggctgc aagctgatga
    13621 agtgagcccg cggcgggggc ggtggcgagc ccgccgtccc cgcgcagcgg gccgacgtca
    13681 tccctctgtc catcgcatcc cggcgtgtcc tgcatgtctg ggagggaagg gttcaaacat
    13741 ggatttcacc tcgttcctga tccagatcct gaacgcgctc cagtacggcc tgctgctctt
    13801 cctggtggcg agcggcctga ccctggtgtt cggcatcatg ggcatcatca acctggcgca
    13861 cggcagcttc tacatgatcg gcgcctacct cgccttcgca ctcagcagcc tgaccggcaa
    13921 cctgatgctg gcgatcgtgc tcggcatccc gctcgccttc ggcttcgggg cgctgctcga
    13981 gaggctgctc ttcgtgcatc tgtacaagcg cgatcacctg cagcaggtgc tgctcaccta
    14041 cgggctgatc ctcatcttcg aggagttgcg cagcctcacg gtcggcgatg acgtgcatgg
    14101 cgtggcgatc cccgagctgt tctcggcctc tatcgcgctc tcggagaacc tctcctaccc
    14161 ggtgtaccgg ctggtgatct cggtggtgtg catcgccctc gccgccggcc tgtggtggct
    14221 gatgcagcgc acccggctgg gcatgatgat ccgtgccggc tcgttcaacc gcgagatggt
    14281 gcagtcgctc ggggtgaaca tcgacatgct ctaccgcacc gtgttcgcgc tcggcgtggc
    14341 gctggcggca ctggccggca tgctcgcggc gccgatctcc tcggtctatc ccggcatggg
    14401 cggcaatgtg ctgatcatct ccttcgtggt cgtggtgatc ggtggcatcg gttcggtgtg
    14461 gggggcgctg gtggcggcgc tgctggtggg gttcgcggat acgttcggca cggtcctgat
    14521 gcccgatctc gcggggctgg cggtctatct gctgatggcg gtcgtgctcc tgtggcgccc
    14581 ggaaggcatc ttcaggaagg ggtgaggcga tgaattcggg agtcgtgacc ttgttcaagc
    14641 tcgccgtgct ggcggggctg atgctgtttc cggcgatcgg atccagcttt tacgtcgagc
    14701 tcgtggcgaa gatcctggtg atggcgatct tcgcgatgag cctggcgctg ctggtgggct
    14761 tcaccgggct ggtcagcctc ggccatgccg cgtacttcgg catcgccgcc tatacggtgg
    14821 cgctgatcgc gcccgagtac gaggcggcca acctgtggtt cgtgctggcg gcctcggtac
    14881 tggcggcggg agcggccgcc ttcttcgtgg ggctgttcgt gctgcgcacc aagggcatct
    14941 atttcatcat ggtgaccctg gccttcgccc agatggccta ctacatcttc cacgacaccg
    15001 cgctcgggcg cagttcggac gggatctacc tgaacgtcaa gccggacgcg agcctcttcg
    15061 gctggacgcc gttcagcctc gacgacccgg cgcagctgta ctacttcatc ctggcggcga
    15121 tggcggcggt gttcgtgctg ctgtccttcg tgctgcgctc gcccttcggg cgcgtgctcg
    15181 ccggcatcca cagcaacgag caccgcatga agtcgctcgg ctacgcgacc ttccgctaca
    15241 agctggcggc cttcacgctg gccggcgcac tggccggggt ggctggcttc ctgtacgcgg
    15301 tgctgttcgg tttcgtgacg ccggaatacc tgtcctggca ccagtcgggc aacgtgttgc
    15361 tgatggtgat cctgggcggg ttggggagcc tcgcgggggc ggtcgccggc gccttcgcct
    15421 tcatcggcct gcaggagatg ttttcggact ggaccaagca ctggcagctg ctgatgggcc
    15481 tggtgatcgt cgccgcggtg ctgttcatgc cgaccggact ggccggcctg ccgcgacgaa
    15541 tcttccgcac ggtcaactgg ggagaagacg atgagtgagg cgatgctggt ggcggaccgc
    15601 ctgacccgcc atttcggcgg gctgaccgcc aacctcgagg tctgcatcac gctcgaacgc
    15661 ggcaagctgc atgcgctgct cgggcccaac ggcgcgggca agtcgacctg tatcaacatg
    15721 ctctcgggcg atctgccgcc atccgccggg cgcatcctgc tcgaggggca ggacgtgacc
    15781 gggctggact cggcggagcg gtcgcaccgc ggcatcgggc gcagctacca gcgcaccaac
    15841 atcttccctc aattcaccgt gctggagaac tgccggctcg ccgcgcagtc gcgcaggccg
    15901 cggccgtggc ggatcttcac cgacgcgatg aagaccaggg acaccgtcga gcgcgcacgc
    15961 gccgccatcg tcgaggccgg cctgggcggg cgcgaacagc gcaaggcggg cctgctctcg
    16021 cacggtgagc aacgccagct cgagatcgcg atggtgctgg ccaccgacgc acgcgtgctg
    16081 ctgctcgacg agccgctcgc cggcatgggc tcggaggagt cggcacagat ggtcgagctg
    16141 ctgcgcgagc tcaagcagaa ccgcgcgatc ctgctcgtgg agcacgacat ggacgccgtg
    16201 ttcgcggtgg ccgacacgat caccgtgatg gtcgagggct cggtgctcga atccggaccg
    16261 ccggagcaga tccgcaacag cgaggaggtc caggcggcct atctcgggga ggaggaacat
    16321 ggctgagatg ctgctcgagg cccgcgacct gcacacctac tacgggtcca gccacatcct
    16381 gcacggggtg agcttctcga tccgcaaggg cgaggcgctc ggcctgatgg ggcgcaacgg
    16441 catgggcaag accacgctgc tgcgcaccat gctcggcctg gtgcggccgc gccacggcac
    16501 ggtgcgcgtc aacggcgacg acatgacgcg cgccaagccg caccgcatcg cgctcgccgg
    16561 ggtggcctac gtgcccgagg ggcgcggcat cttccccaac ctgagcgtgc gcgagaacct
    16621 cgtcatggca gcgcgcgcgg gcgtggacgg gcagcgcgag tggactttcg agcgcgtgat
    16681 ggagaccttc ccgcgcctgg gcgagcgcat cgacaacggc ggcggccagc tctccggcgg
    16741 cgagcagcag atgctcacga tcggccgcgc cttgatgacc aaccccgacc tgctgatcct
    16801 cgacgaggcc accgaggggc tggcgccgct gatggtcaag gagatctgga aggtgatccg
    16861 caccatccgc gactccggca tcgccaccgt ggtggtggac aagaaccact ccgcggtcac
    16921 cgcgctgacc aaccgctcga tgatcctggt caagggcgag gtggtgttcg atgggccgag
    16981 cgaacaggtg cgccaggatc ccgcgctgat ccgcaagcac ctcggggtct gatgcatccg
    17041 cgggcgggcg cgtgcccgcc cgcctgcgcg tgcttcctgc gccgcacgca gcggcgcgct
    17101 cgcggcctca atcgtccgcc agcaccgccg tgacctcgat ctccaccttg gcgccgtcct
    17161 cgacgaagcc ggccacctgc accgcgctca tcgccgggta gtgatggccc accaggtcgc
    17221 ggtagaccgc gccgatctcg cccaggcggg cgttgtattc ggctgtattg gccagatacc
    17281 aggtcatgcg cacgatgtcg gtcgagcgcg cgccgccggc gtccaggacg gcgagcacgt
    17341 tgcgcagcgc ctggcggatc tgctcgacca ggtcctcgct gcggaagacc tcgtccgcgt
    17401 cccagccgac ctggccggcg acgaacagca tccgtccgct cgcgaccacg ccattggcat
    17461 agcccttcgg tcgtttccag cctgcgggtt gaagaatctg catgtctgtc tcctcgagtg
    17521 cggttgcggc gatgcgcgtt ggcggcagtg cgcgctcgcg ctgcatgtta aatagtgcat
    17581 cttaagaaaa cattgtgcaa taaaatgcag aatattgccg ctcgtggtcg agcgggtgtc
    17641 agccgtggag acctgcccac tcatagcgca agtcttatag aggacttttg cgccacaccc
    17701 ttgaccgacg ccgcgatcga aagcatcctt cgaaggttat gcgcccgcga atacgggcgt
    17761 gttcctagac aaccccgagc cagtgagtgc gaaagatgac cgaacgagtg agttgccagc
    17821 gtctgcaggt cgcagcgaac ctgaagcgtt tcattgaaga agaggccctg ccgggcagcg
    17881 gtgtcgacgc cgccgccttc tggtccgggt tcgatgtgct ggtacacgat ctcgcgccga
    17941 agaacgcctc gctgctcgcc gagcgcgacc gcatccaggc cgaggtcgac gcctggcatc
    18001 gcgcccatcc cggcccgatt gccgacatgg ccgcctacaa ggccttcctg tcctcgatcg
    18061 gctacctgct gccggttccc gccggcgcca aggccaccac caccaacgtg gatgacgagc
    18121 tcgccgtgca ggccggtccg cagctggtgg tgccggtgat gaacgcgcgc tacgcgctca
    18181 acgccgcgaa cgcgcgctgg ggctcgctct acgacgcgct ctacggcacc gacgccatcc
    18241 cgcagaagga cggcgccgag ctcaccaagg gctacaaccc ggcgcgcggc gccaaggtca
    18301 tcgccttcgg ccgcagcgtg ctcgaccagg ctgcgccgct cgccggcgcc tcgcacgccg
    18361 acgcggcggg ctacgcggtc gagggcggca agctggtggt gaagctgcag aacggctcga
    18421 ccaccggcct gcagcaggcg gagaagttcg tcggcttcca gggcgaggcc gccgcgccga
    18481 gtgccgtgct gctgaagaac aacggcctgc acatcgaggt gcagatcgac cgcaacggcg
    18541 ccatcggcaa gaccgacgcc gccggcgtga acgatctgct gatggaagcc gcgctgtcga
    18601 ccatcatgga ctgcgaggac tcggtcgccg cggtggacgc cgacgacaag gtcgtggtgt
    18661 accgcaactg gctcggcctg atgaacggca cgctggaaga caccttcgag aagggcggca
    18721 agccgatgac gcgccgcctg aacgccgacc gcgagtacac cggcgccgac ggcaagccgg
    18781 tcaagctgca cggtcgcgcg ctgctcttcg tgcgcaacgt cggccacctg atgaccaacc
    18841 ccgcgatcct gtggggcgag ggcaaggaga tccccgaggg cgtcatggac gcggtcgtca
    18901 ccacgctgat cgccaagcgc gacctcgagc gccgcggcaa ttcgcgcaag ggcagcatct
    18961 acatcgtcaa gcccaagatg cacgggccgg ccgagatcgc gttcgccgac gagctgttca
    19021 cccgcgtcga gcagctgctc ggcctgccgg gcaacaccgt caagctgggc atcatggacg
    19081 aggagcgccg taccagcgtc aacctgcgcg cctgcatcgc cgccgcgccg gcgcgcgtgg
    19141 ccttcatcaa caccggcttc ctcgatcgca ccggcgacga gatgcacacc tcgatggagg
    19201 ccggcccgat gatgcgcaag ggcgacatca agaacagcaa gtggatcgcc gcctacgagc
    19261 gccgcaacgt gctcatcggc ctcgccgccg gcctgcgcgg ccgcgcccag atcggcaagg
    19321 gcatgtgggc catgcccgac ctgatggccg cgatgctcga gcagaagatc ggccatccca
    19381 agtccggcgc caacaccgcc tgggtgccgt cgcccacggc cgccaccctg catgcgctgc
    19441 actaccacca ggtcagcgtg gccgcggtgc agcaggacat cgagaagctc gacctggaca
    19501 aggaggcgga ggtgctcctc gacgacctgc tcaccatccc ggtggtcgcg aaggccgagt
    19561 ggagcgcgac cgagcgccag caggagctcg acaacaactg ccagggcatc ctcggctacg
    19621 tggtgcgctg ggtggagcag ggcgtgggtt gctcgaaggt gcccgacatc aacgacatcg
    19681 gtctgatgga agaccgcgcc acgctgcgca tctccagcca gcacatcgcc aactggctgc
    19741 gccatggcgt ggtgcccgcc gagcaggtcg aggccacgct gaagcgcatg gccgcggtgg
    19801 tcgatggcca gaacgcgggc gacccgctgt accgcccgat ggcgccgaac ttcgacgact
    19861 cggtagccta cgcggccgcg cgcgcgctga tcttcgaggg ctgcgcccag cccagcggct
    19921 acaccgagcc cctgctgcac cgctaccgcc agcagttcaa ggcgaagatc ggcgcctgaa
    19981 gggcgccgtg ttcgcggctg ccgccgctcc tacagggcgg ctcaagcgcg ccggttcatg
    20041 caggagcgcc ggcaggcgcg aatgcggcgg tcgaggtccg ctcacgcgca tcgcttgctg
    20101 gatctctccg tgttcgcggc cgccgccgct cctnnnnnnn nnnnnnnnnn nnnnnnnnnn
    20161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    20221 nnnnnnnnnn nnncgctcac gcgcatcgct tgctggatct ctccgtgttc gcggccgccg
    20281 ccgctcctac agggcggctc aagcgcgccg gttcatgcag gagcgccggc aggcgcgaat
    20341 gcggcggtcg aggtccgctc acgcgcatcg cttgctggat ctctccgtgt tcgcggccgc
    20401 cgccgctcct gcagggcggc tcaagtgcgc cggttcatgc aggagcgccg gcaggcgcga
    20461 atgcaggcgc gccgcgggcg atgtggtcga aaagggtgac gacgcatccg cacggctacg
    20521 cattgccttc cgcagcaatc tttccgtagc aacgaaaaag ggcgccgatc ggcgcccttt
    20581 ttcgtcatgg agttacgtgt gtgcccaggc gctcaccaca gctgccacca cggccggtcg
    20641 tcctccgggc caccgcggaa gtaaacgctg tcagggaagt tcttgcgcat gacgcggtcg
    20701 gcgtcgtcgc gcagctgcgc catgccgagc ttgtcgtagc tcatcaccat caggaacagc
    20761 gcctcctcga tcgcgggggc ctgcgggaag ttgctcaccg cggtctgcgc gcggttgatc
    20821 gccgcgacgt aggcgccgcg gttgtagtag tagcgcgaga cgtgcacctc atgcgaggcg
    20881 agcgagttga tcaggtactg catgcgcgcc cgcgagtctt ccgcatagcg gctcgcgggg
    20941 aagcgctcga ccagctcgcg gaagctgtcg aaggcctcgc gcgcgccctt ggggtcgcgc
    21001 tcggagagat cctggcgcga caggccggcg agcaggccga ggtcttcgtt gaagttgacc
    21061 agacccttga ggtagtaggc gtagtcgacg ttcgggtggt tgggatgcag cttgatgaag
    21121 cggtcggccg cggcgagcgc gagcgcctgc tcgccctgct tgtagtacgc ataggccacc
    21181 tcgagctggg cctgctgggc gaagcgaccg taggggtagc gtgcctcgag cttctcgaac
    21241 agcgtcaccg cgcgctcgta gccgccttcg ctcatcgagg ccttggcctc ggaataaagc
    21301 ttctgcgcgt tccagcccgc agtctcgtcg acctgctcgg gcagcaggcc gcagccgcca
    21361 agcagcaagg cgccgatcag cgcggctttt gccgttaaac ttccgggggt gaacctggcc
    21421 atcgaagaca ctcgcgtgaa tgaacgcgcc gattatatcc cagcagtcct cccgtccgac
    21481 gtcctctccg accttccggc cgacgagctc gaggcctgcg agacgctgac gattcctgcc
    21541 gaactcggcg ggctgcgcct cgaccaggcg ctcgcgcggc tcttccccca gcactcgcgc
    21601 agccgcctgc agggctggct caaggcgggc tggatccgcg tcgacggcgg cagcccggac
    21661 gcgcgccgca aggtttgcgg tggggagtgc gtggagatcg acgcgccgcc gccccccgag
    21721 ctcgctgccg agctgcccga ggacatcccg ctcgcggtgg tgtacgagga cgaggacctg
    21781 ctggtgatcg acaagcccgt cgggctggtc gtgcatccgg gcagcggcaa ctggagcggg
    21841 accctgctca acgccttgct gcaccgcaac cccgggctcg ccgggctgcc gcgcgccggc
    21901 atcgtgcatc ggctcgacaa ggacaccagc gggctgatgg tggtggcgaa gacgctcgcc
    21961 gcgcagaccg agctcgtgcg ccagctccag gcgcgcaccg tcgggcgcca ctaccgtgcg
    22021 ctggtgcagg gcgagctgag cgccggcggc acggtcgatg cgccgatcgg gcgtcacccc
    22081 acgcagcgca cgcgcatggc ggtcgtcggc aacggccgtc cggcagtcac gcattaccgc
    22141 gtcaccgagc gcttttcccg ggcgaccctg gtcgagtgcc gcctggagac cgggcgcacc
    22201 caccagatcc gcgtgcacat ggcgcacatc ggccatcccc tggtgggcga cccgctctat
    22261 ggcgcgcgac gctgcggcga tgcgcgcctc gacggttttc cgcgccaggc cctgcacgcc
    22321 ttccggctcg gcctcgtaca tccgcgcagc ggcgaggcga tgcgctggga ggtgccgctg
    22381 gcaacggatt tcgccacgtt gctggacgaa ctgcggggtg cgccgcgatg agcctgcctc
    22441 cgcacggcta ccagccattc gcccccggcc tgctgcgtcc ggagtggcac ctgccgcccg
    22501 gggtgcatgc gatggtgagc acccgcgagg gcggcgcgag cctggcgccg tgggcgagct
    22561 tcaacctcgg cagccacgtc ggcgacgatg cgcgcgcggt ggcggccaat cgcgcgcggc
    22621 tgtgcgcggc gactggcgcc gaaccggtgt ggctcgagca ggtgcacggt tgcgcggtcg
    22681 cggacgccga ctgcaccgcg ggcgtgcccg cggccgacgc ggcggtcgcg cgggctaccg
    22741 ggcgggcctg cgcggtgatg accgccgact gtctgccggt gctgttctgc gacgccgacg
    22801 ccagcgtggt cgccgccgcg catgcgggct ggcgcggcct cgccgccggg gtgctggagc
    22861 gcacggtgga gcgcatgggc gtggcgcccg ggcgggtgcg cgcctggctg gggccggcga
    22921 tcgggccggc ggccttcgag gtcggcgacg aggtgcgtgc ggccttcgtg ggtgcggatc
    22981 cgggagcggc cgctgcattc gtgccgggtg tggcgccggg gaaatggctg gccgatctct
    23041 tcatgctcgc ccgccgtcgc ctcgtcgccg cgggcgtggg ccggatcgat ggcggcgggg
    23101 tgtgcaccgt ggccgatccg gggcatttct actcctaccg acgcgacggg acgaccgggc
    23161 gtttcgcctc gctgatctgg ctggaggagg ggcggcgcgg cggaatcacg tgagcgcgcc
    23221 gtcgccccga tccgtctcgc atgaccgcct tagggcttgc ggctattgat cggcgtcagt
    23281 ttcggctcta tcgttgcgtt cgagtgcttc gcgctcctgc tccaggcgac gacgtcggcg
    23341 ggccggggtg ccgaacagcc acaggaacaa ggccaggggg gcgagccccc agaacacgaa
    23401 ggtgagcacg gcggcaacga tcgtgtcctc cgccgcggcg acgaggatga cgacgtagag
    23461 ccaggcgatc ggaatcaggt acatgggtgg attctagcgc gcgccgggtg ccggtgccgg
    23521 aggatccctg acagggcagg aaaccgcgac cccgaccccg gagcgggcgg gtgcggcctc
    23581 aggagaatgg gatgtcggat tcgacgggca agcaggtgcc gccgggcatg caggcgatcc
    23641 tcgccgccgg gcaggcgatg gcgcagggct tcttcgatgc gctcgcgcgc cagcacgtgg
    23701 cgatgcagga ctcctcgggg gtggcggcgc agaagctgcc gatgcccgag acggaagtga
    23761 tggcttcgct gcaccaggcc ttcgccgaga agcatgccga gctgtggtcg tccatgcttg
    23821 cgcgtacgcc gggtgaggcg ggtcctgcgg ttgtgcagcc cgagccgggc gacaagcgct
    23881 tcgccgcgcc tgaatggtcc gagagtccgg ttttcgacta catgcgccag gcctacctgc
    23941 tcaacgccgg cttcctgcgc cagatggcgg atgcgatgcc gatcgccgac ggccgcgcca
    24001 aggcgcgcat gcagttcctc acccgccagt acatcgacgc gctgtcgccg agcaacttcg
    24061 cggcgaccaa ccccgagttc atcaagaccg cggtcgagac caagggcgag agcatcgcgc
    24121 gcggcatcca gaacctgctc ggcgacctcg agaagggccg catctcgatg accgacgacg
    24181 cggccttcga gatcgggcgc aacctcgcgc tcaccccggg ctcggtcgtg tacgagaacg
    24241 agctcatgca gctgatccag tacgcgccgc tgacggagaa ggtcgcgcag gcgccgctgc
    24301 tgatcgtgcc gccgtgcatc aacaagttct acatcatgga cctgcagccc gagaactcgc
    24361 tcgtgcgctt cgtcgtcgag cagggcttca cggtcttcct ggtgtcgtgg aagaacccgc
    24421 gtcccgacac cggcggccat tacacctggg acgactacct cgacaagggg ccgctcgcgg
    24481 cgctcgaggt cgtgcgttcg atcacccgcg tcaagaagcc caacgtgctc ggcttctgcg
    24541 tcggcggcac catcctcacc tcggcgctcg cggttgcgcg cgcgcgcggc gaggagccgg
    24601 tggcgagcct gacgctgatg accacgctgc tcgacttctc cgacgccggc gagctcggct
    24661 gcctggtcga cgaggcgagc gtgaccgcgc gcgaggccgc gatcggcaag ggcggggtgc
    24721 tcaaggggca ggaactcgcc aacgtgtttt ccttcctgcg tgccaacgac ctcgtctggc
    24781 agtacgtggt cggcaattac ctcaagggca acaagccggt cgccttcgac ctgctgtact
    24841 ggaactccga ctcgaccaac ctgccagggc ccttcctcac gtggtacctg cgcaacatgt
    24901 acctcgagaa caacctgcgc gtgccgggca agctgcgcat gctcgggcag aaggtcgacc
    24961 tcggcaaggt ggacgtgccg gcctacctga tggcagcgcg cgaggaccac atcgtgccgt
    25021 ggaagagcgc ctatctggcg cgcaacgtgc tgggcggcga aaccaccttc gtgctggggg
    25081 cgagcggcca catcgccggt gcgatcaacc cggcctcgaa gaaccgccgc agctactgga
    25141 ccgccgacgt gcgcccggcc gatcccgacg agtggttcga cggcgcggcc gagcacaagg
    25201 gcagctggtg gctgcactgg gccgagtggc tgcgcggcca cggcggcaag gaggtggccg
    25261 ctcgcggccg cctgggcagt acgaagtacg agccgatcga gccggcgccg gggcgctacg
    25321 tgaaggagcg ttcctgacgc ggcgggagac gattttcagc gttcggcggc agcgcatcgg
    25381 gcggtcgctg ccgtcgtgtt cgacgaccgt ccagcatcac aacaggaccc cgcataggga
    25441 gaggagaaga agatggcaag agttgcactg gtaaccggcg gcatgggcgg tctcggcgag
    25501 gcgatctgca tcaagctcgc ggcgctcggc tacaaggtgg tcacgaccca ttcgcccagc
    25561 aacaccaagg ctcaggagtg gctgcagacc atgaacaaca tgggctacgg cttcaaggcc
    25621 tatccctgcg acgtggccga tttcgattcc tgcaaggcct gcgtggagca ggtcaccaag
    25681 gaggtcggcg cggtcgatgt gctggtcaat aacgccggca tcacccgcga catgaccttc
    25741 aagaagatga ccaaggccga ctgggatgcg gtcatcagca ccaacctcga ctcggccttc
    25801 aacatgacca agcaggtcat ggacggcatg gtcgagcgca agtggggccg cgtgatcaac
    25861 gtgtcctcgg tgaacggcca gaagggcgcc ttcggccaga ccaactacgc cgccgccaag
    25921 gccggcatgc acggcttcac caaggcgctg gcgctggaag tggcgcgcaa tggcgtcacc
    25981 gtcaacacca tctcgccggg ctacatcggc accaagatgg tgatggcgat cccgcaggag
    26041 atcctcgact ccaagatcct gccgcagatc ccggtgtccc gcctgggcaa gccggaagag
    26101 atcgccggcc tggtcgccta cctgtcctcg gacgaggccg ccttcgtgac cggcgccaac
    26161 atctcgatca acggcggcca gcacatgttc tgatccgtcg gcggccgatt ccggtaccgc
    26221 agcgtggcgc gctccactgg ggcgcgccat ttttttgtgc gcgccgtggc cgggaagatc
    26281 gctattgcat cgcaacatga gttgtgaaac aggggctata atccgcgcgt gaggtggctg
    26341 atgcgctgcc gcatccacga ccgaagcgcg cgccggctgt cccggttcgc aggcggcctt
    26401 ggttttttac aaatgctcct gaaggatttc aagatgtccc agaaaatcgc tcttgtcacc
    26461 ggcgccatgg gtggtctcgg cacggcgatc tgccagtcgc tgtccaagga cggcttcaag
    26521 gtcgtggcca actgcctgcc gaacttcgag caaaaggacg cctggctgtc cgcacagcgc
    26581 gacctcggct tcgacttcgc cgccgccgaa ggcgacgtgt cgaactacga gtcgtgcgcg
    26641 gcgatggtcg ccaagatcga agccgacatc ggcccgatcg acgtgctggt gaacaacgcc
    26701 ggcatcaccc gcgacaagtt cttccccaag atggagaagg gccagtggga tgcggtgatc
    26761 aacaccaacc tgaacagcct gttcaacgtc acccaccacg tctcctccaa gatggccgag
    26821 cgcggctggg gtcgcatcat caacatctcg tcggtcaacg gcgtcaaggg ccaggcgggc
    26881 cagaccaact actcgaccgc caaggcgggc gtgctgggct tcaccaaggc gctcgccgcc
    26941 gaactggcca ccaagggcgt gacggtcaac gcgatcgccc cgggctacat cggcaccgac
    27001 atggtcatgg cgatccgcga ggacatccgc cagggcatca tcgacaccgt gccgatgaag
    27061 cgcctcggcc gtccggacga gatcggcgac ctgtgcgcct acctcgcctc cgacaaggct
    27121 gcctacatca ccggtgcgac catcaacatc aacggtggcc tgcacatgtg ctgatgttgc
    27181 gccgtgtcat gcgcgaaatc acgcaacccc gtcgaaagac ggggtttttt cgtggtttcg
    27241 atgtcgcagc gcgatataat ttttttgcac agagcgaaga caccgccgcc gaggagatgg
    27301 agaaatgccg gaacagcagc gcttgatcaa gaagtacccg aaccgccgtc tctacgacac
    27361 gcggaccagt tcctacatca ccctggccga cgtcaaggat ctggtgctca accacgagca
    27421 cttccaggtg gtggatgcga agaccggcga ggacctgacg cgcagcatcc tgctccagat
    27481 catcctcgag gaagaggccg ggggcgcgcc gatgttcacc agcgacctgc tcgcgcacat
    27541 gatccgcttc tacggcaacg ccatgcaggg catgatgggc aagtacctgg agagcaacat
    27601 caaggccttc accgagatgc aggtcaagct ccaggaccag gcgcgcgcga tctacggcga
    27661 gaacagtccg gtgggccagg acctgtgggc gcagttcctc aacttccagg ggcccgcgtt
    27721 gcagagcatg atgggcgcct acgtcgacca gtcgaagaag atgttcgagc agatgcagac
    27781 gcagctcgag agccagacgc gcaacatgtt caccggcttc cagttccccg gctacgtccg
    27841 tcccgaggac gagcccgccg cgcccaaggg cgacggcaag aagtaagcgg cgccgcgtgc
    27901 cgccgaggct gccgccgccc cgacccgaca ggttttttgc atgaccacct tcaagacccc
    27961 cgacctgccg cgcgtcggct tcgtctccct cggctgcccc aaggcgacgg tcgactccga
    28021 gcacatcctg acccggttgc gcgcggaggg ctattcgatc tcgggtagct acgacgacgc
    28081 cgacctggtc gtcgtcaaca cctgcggctt catcgacgct gcggtcgagg agtcgctcga
    28141 cgcgatcggc gaggcgctcg ccgagaacgg caaggtcatc gtcaccggct gcctcggcgc
    28201 caaggacgac gtgatcctcg ccgcgcaccc gcaggtgctc gcggtcaccg gcccggatgc
    28261 caccgaggag gtcatgcacg cggtgcatcg ccacctgccc aagccgcacg accccttcac
    28321 cgacctcgtg ccgccgcagg gcatccggct cacgccgcag cactacgcct atctcaagat
    28381 ctccgagggc tgcaaccacc gctgcagctt ctgcatcatc ccgtcgatgc gcggcgacct
    28441 cgtcagccgg ccgatccacg aggtcatgcg cgaggccgag gcgcttgccg acgccggcgt
    28501 caaggagttg ctggtgatct cgcaggacac ctcggcctac ggggtggacg tcaagtaccg
    28561 caccggcttc tggggcgggc gcccggtcaa gacgcgcctg ctcgacctgg ccaaggcgct
    28621 cggcgagctc ggcatctgga tccgcatgca ctacgtgtat ccgtatccga gcgtggacga
    28681 cctgatcccg ctgatggccg agggaaagat cctgccctac ctggacgtgc ccttccagca
    28741 cgccagcccg cgcatcctca aggccatgaa gcgtccggcc aacgccgaga acgtgctcga
    28801 gcgcgtgcgc aagtggcgca gcatctgccc cgagctcacc atccgctcga ccttcatcac
    28861 cggcttcccc ggcgagaccg aggaagactt cgagatgctg ctgaacttcc tcgaagaggc
    28921 ccagctcgac cgcgtcggcg ccttcgccta ttcgccggtc gagggcgcga cggccaacga
    28981 gctgcccggc gcggtgccgg acgaggtgcg cgaggagcgc cgcgcgcgcc tgatggactt
    29041 ccaggaagac atctccaccc agcgcctcga ggccaagatc gaccgcgaga tgaccgtgct
    29101 ggtcgacgag gtcgacgagg agggggcgct cgcgcgttcg ccgggcgacg cgcccgagat
    29161 cgacggtctc gtcatcatcc ccgagggcga cggcctcgcg ccgggcgact tcgtgcgggt
    29221 gcgcatcacc gactgcgatg tgcacgacct ctacgccgag cgcatcgagt aagggcggct
    29281 tcgccgcgcc ggagcccccg tcgtggtgag cggcgcgggc gcggtcggcc tggcttgcgc
    29341 cgaaccttcg accgcagggc cggtgatcgg gctcgcgctc ggcagcggcg ccgcgcgcgg
    29401 ctgggcgcat ctgggcgtgc tgcaggagct cgcgcgcgag ggcgtggtgc cgcagatcat
    29461 caccggctgc tcgatcggcg ccttcgtcgg cgccgctgcg gcctcgggcg acctcgccaa
    29521 gctggtgcgc tgggccgaga cgctcaagtg gcaggacgtg gtgtcgctgc tcgacgtgtc
    29581 gctgcgcggc ggcctgatca agggccagaa gctgatcgac ttcttcgagc gcaacttcgt
    29641 cgaccgcgac ttcaccgaac tcgaccagcg cttcgcctgc gtcgccaccg aactctccac
    29701 cgggcgcgag atctggcttc acgagggcag cgtctccgcc gcggtgcgcg cctcgatcgc
    29761 gctccccggg ctgatgaccc cggtgctgca ccagggccgc atgctggtcg atggcggcct
    29821 ggtcaatccg gtgccggtgt cgctttgccg agcgatgggg gccgacgtgg tgatcgcggt
    29881 ggacctcggc tcggacatgg tggggcgcgc cagccggcgc tcggcggtcg cgcccgcgcc
    29941 ggtcgaggag accgaggccg ggtggaccga gcgcctactc gcccgcttcg gcttcgccag
    30001 cgacgaggag cccggcgcac cggcgcggcc cctggctgcg gacgacaatc ttccctcgct
    30061 ggtctcggtg atcagctcca gcatcaacat catgcaggtc cgcatcgcgc gcagccgcct
    30121 cgccggcgag ccggccgacc tgctggtgtc gccgcgggtg agccagctcg gcctgatgga
    30181 ttaccaccgc gccgacgagg ccatcgccga gggcgtggcg gcggtggcgc gggtgaggcc
    30241 gctgctgcgc gagctgctcg gcggcaccaa cgagtgagga tcggatgagc gatgaactga
    30301 acgcgcgcct gcgtacgatc gtcggcgcgg cgaacgtgct cgaggccgag gccgacatgg
    30361 cgcccttcct gagcgactgg cgcgggcgct accacggccg cgcgcgcgcg gtggtgcgtc
    30421 cgcgcgacac cgccgaggtg gccgcggtgg tcgccgcctg cgcgcaggcg ggagtggcga
    30481 tggtgccgca gggcggcaac accgggctgt gcggcggcgc gaccccgctc gtcgacggcg
    30541 cggcggtggt gatcagcctg gcgcgcatga accgcatccg cgcgctcgat gccgacaacg
    30601 acacgctcac ggtcgaggcc ggctgcacgc tcgctgccgt gcaggaggcg gcgcaggcgg
    30661 ccgggcgcct gttcccgctc tcgctcgcct cggagggcag ctgcctgatc ggcggcaacc
    30721 tgtcgaccaa cgccggcggc gtgcaggtgc tgcgctacgg caacacgcgc gagctggtgc
    30781 tcgggctcga ggtggtgctg cccgacggtc gtgtgtggga cggcctgcgc ggcctgcgca
    30841 aggacaacac cggctacgac ctgaagcagc tcttcatcgg cgccgagggc accctgggca
    30901 tcgtcaccgc cgcggtgctc aagctctttc cggccatccg cagccgcgcc atggcctggg
    30961 tggccgtgcc agacccgcgc gccgcggtgc gcctgctcgg gatgctgcgc gcagtgtgcg
    31021 gcgagcgcgt cagcgccttc gagatcgtcg gccgcacggc gctcgggctg gtgctccagc
    31081 acattccggg cgcgcgcgat ccgctcgccg gtgcgccggc gtggtccgtg ctggtcgagc
    31141 tctccgaccc cgatgtcgat gcgccgctcg acgcgcaact gcaggccgtg ctgggggagg
    31201 cctgcgcgca gggcctggcc gccgacgccg cggtggcggc gagcgcagca caggcgcagg
    31261 ccctgtgggc gctgcgcgag gacatctccg aggcgcagcg catcgagggc gtcagcatca
    31321 agcacgacgt ctcggtgccg gtgagccgca tccccgagtt cctcgagcgc gcgggcgcgg
    31381 cgctcgccgc gcgctggccg gacgttcgcg tggtggcctt cggccacatc ggcgacggca
    31441 acctgcacta caacctgtcc aagcctgcgg ccgacgacaa cgccgccttc atcgcacgca
    31501 ccgccgaggt caatcgcatc gtgcacgacc tggtgtgcga gctcggcggc tcgatctcgg
    31561 ccgagcacgg cctcggccag ctcaagcgcg aggaggtgct gcgctacaag cccgcgctcg
    31621 agatggagct gatgcgacgg gtgaagcagg ccttcgatcc agccggactg atgaacccgg
    31681 gcaaggtgct gtagaaattt caaaaagggg gtttacaggc ctgggggtgc gacctataat
    31741 gcgcgctctt cggtgccggg ggtatagctc agctgggaga gcgcttgcat ggcatgcaag
    31801 aggtcagcgg ttcgatcccg cttacctcca ccaaactgaa gaatgcagtc cccatcgtct
    31861 agaggcctag gacaccgccc tttcacggcg ataaccgggg ttcgaatccc cgtggggacg
    31921 ccaacaaagg cggctcgaca atgttcgggt cgcgaccggc ggaagccgga gcaggtcagc
    31981 gcggagtggt agttcagtcg gttagaatac cggcctgtca cgccgggggt cgcgggttcg
    32041 agtcccgtcc actccgccag tttcaaacgc agggccttgg tcctgcgatg tccaggaggt
    32101 gacgctcccg gacagttgcg gtgggctttg ccagaagcta taatcaccga ctcgttgtgg
    32161 gggtatagct cagctgggag agcgcttgca tggcatgcaa gaggtcagcg gt
//
LOCUS       DAOTIN010000031        30270 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_1703_length_30270_cov_9.194043, whole genome shotgun sequence.
ACCESSION   DAOTIN010000031 DAOTIN010000000
VERSION     DAOTIN010000031.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 30270)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 30270)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30270
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1703_length_30270_cov_9.194043"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(5..1645)
                     /locus_tag="P5537_06795"
     CDS             complement(5..1645)
                     /locus_tag="P5537_06795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HRV77785.1"
                     /translation="MSQNAYQQGLDKNAANYVPLSPLSFIERTAMVYPTRTSVVHGTL
                     AYTWSQTYERCRRLASALVAHGVKKGDTVACMLPNVPPMFEAHFGVPMTGAVLNTLNT
                     RLDADAIAFMLQHGEAKVLITDPEFAGVVRAALELLPGDKPLVIDALDPEYPGEERVG
                     TLLYEDFLAGGNPDFQWKLPADEWDAIALNYTSGTTGNPKGVVYHHRGAYLNAASNII
                     SWGMPQHSSYLWTLPMFHCNGWCFPWTMAANAGINVCLRKVDPALIYELIRRHKVTHM
                     CGAPIVYGMLINAPDGLRAGIEHSVAGLIAGAAPPAAIIEGAERIGFDITHVYGLTET
                     YGPASVCAKHPEWDALPIDRRAERNGRQGVRYHMQEAITVLDPVTMEPVPADGETMGE
                     IMFRGNLVMKGYLKNEKATQESFAGGWFHTGDLAVMHPDGYVKIKDRSKDVIISGGEN
                     ISSLEVEEVLYRHPAVLTAAVVAKPDEKWGEVPAAYIEVKEGAGVTADDIIAHCREHL
                     ARYKVPKFIEFCVLPKTSTGKIQKFALREMAKSASAIE"
     gene            complement(1793..2059)
                     /locus_tag="P5537_06800"
     CDS             complement(1793..2059)
                     /locus_tag="P5537_06800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HRV77786.1"
                     /translation="MNATHSKPIPQPHERIRLIGTPVGRMVRIDDFGDEIDPLQREQL
                     HAYGLSAAHAVKVLQQQPMTVLLCEHVELAIEHAVSRHIWVQPA"
     gene            complement(2072..>3274)
                     /locus_tag="P5537_06805"
     CDS             complement(2072..>3274)
                     /locus_tag="P5537_06805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition domain-containing
                     protein"
                     /protein_id="HRV77787.1"
                     /translation="LARERGGAAEALARTVTRQAAGKDRTLSMLLGRVAVHRLWGWPM
                     LLGVLYLVYLFVGDFGASTLVGLLEEDFFGEVLNPAVTDFVTRHVSTPWLADLIVGEY
                     GLWTMGMTYALALILPIVTTFFLAFGVLEDSGYFSRLSVIANRMFAAIGLNGRAVLPM
                     VLGLGCVTMATLTTRILHTPRERLITIYLMALAIPCSAQLGVVLGLLGGISFGATVIW
                     VLAIVGVLLFTGWLASKVVPGRRVPLVTELPPMRMPVLGNVLKKTGGRLKWYLIEVIP
                     LFLIGTLIMFGLDRSGALPWIIEAGEPLVVGWLGLPPEASAAFVMGFLRRDFGASGLF
                     ALQSELSMIQAVVGMVTITLFVPCIASLMMIIKEQGMKVAALMLAMIIPTAFLIGGLL
                     NHGLRLIF"
     assembly_gap    3275..3374
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<3375..3697)
                     /locus_tag="P5537_06810"
     CDS             complement(<3375..3697)
                     /locus_tag="P5537_06810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB small GTPase domain-containing protein"
                     /protein_id="HRV77788.1"
                     /translation="MDCATSPAPATAAVLRTLALVGHPNVGKSVLFHRLTGTYVTVSN
                     YPGTTVEVSRATPRFDREASLLDTPGVLALPSRSDDERATMRALLHEDMRTLIQVGDA
                     KNLRRT"
     gene            3938..4549
                     /gene="rpsD"
                     /locus_tag="P5537_06815"
     CDS             3938..4549
                     /gene="rpsD"
                     /locus_tag="P5537_06815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004336616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HRV77789.1"
                     /translation="MSRYTGPRLKVMRALGTELPGLSRKPLGERNYPPGQHGQRPKRK
                     SGFGVQLIEKQKLRFNYGLGEKQIQRLFREAKRDRGPTGDKLLELLERRLDNFVFRAG
                     FAPTAVAARQLVRHKHVLLNGRAVNIPSIRIRPGDRIQVTERARSIPVVVESLAEPAL
                     ARPEWLVFDEAALAATVTRTPAPDEVPFPVDVQQVVEYYAVRL"
     gene            4546..4842
                     /locus_tag="P5537_06820"
     CDS             4546..4842
                     /locus_tag="P5537_06820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77790.1"
                     /translation="MSAQASANWRSGAATEGPEYDTDPELALAAVLQLLSRFPARRSP
                     ALAQAIASHFRVIGSDPRLSACLRDCAARLVRDWEAYAVLGEAGDLSQDSRVLH"
     gene            5098..5475
                     /locus_tag="P5537_06825"
     CDS             5098..5475
                     /locus_tag="P5537_06825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77791.1"
                     /translation="MKRLILAATLALAPLASPAWASGAGERSAHFEGKPSATLAQAVA
                     NFSEYNLKLNAILDGKVTDADMAEVHQLTYTLENALKKINEEMSALAGTLEEVHLASE
                     KLDRDAVLKHGRAYLSVSGQVVR"
     gene            5659..6342
                     /locus_tag="P5537_06830"
     CDS             5659..6342
                     /locus_tag="P5537_06830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77792.1"
                     /translation="MSHRKSGLRPIVLASLFAFCSAPAFAERPMAVDDAGTLERGGAK
                     LEFGWSRDDAVRGYEGAAGFGPIDDVEVEVGFGRAKDRDADPDAKIRAVGAAIKWGPL
                     QSETGLSAGLKYEYGRERVSGEGSSRVDALAGLATWAFEQGPRVHVNLGREWARDDED
                     LNFWGVGLDVPLTERLDFVVETFGAEHAGPDRQVGLRYTIADGVKISGAVGRGNDRNI
                     ANVGVAWEF"
     gene            6375..6716
                     /locus_tag="P5537_06835"
     CDS             6375..6716
                     /locus_tag="P5537_06835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-associated domain-containing
                     protein"
                     /protein_id="HRV77793.1"
                     /translation="MVSFKELRGFLRDVRIAHHIRGRIRLKLDGRGGAIDLPKVEAGA
                     FQSLLDRTPGVRSVQVNLLARSCTVHYDPEVIPEHAWGDFLAGAASEAAAVLERILHD
                     SYREIGNAELR"
     gene            6700..7395
                     /locus_tag="P5537_06840"
     CDS             6700..7395
                     /locus_tag="P5537_06840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HRV77794.1"
                     /translation="MQNYDEFILRAQRIDPRAPYPVVHQAVRIALYDEYAARSFYARV
                     AEAFGARPPFANIVRSEEQHIAVLLGLCERFGIPRPLDPFPQETTVAPTWLANCQRAV
                     NGDIANVRLYAYLLTQVAEPEIRQVFQRLQAASLQNHLPAFRQAAAAAQAQENYHAAH
                     GIPPQQAYVRHGPLSDFLETAFSQLGPYAGPLGLFSPLLRRAHPAMLAGMVTGGAGVY
                     LLKDRIGRHRKEN"
     gene            7397..7723
                     /locus_tag="P5537_06845"
     CDS             7397..7723
                     /locus_tag="P5537_06845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77795.1"
                     /translation="MFPLFPFVAGVLTGAVALRLIKTDKTKAGLDKAQDKLRDATVSS
                     LEAIEHASARARKRLTAAEADEDGESMPAEAAEPSAPAARKRAPRAAKAAPKVDAAAG
                     KEDAES"
     assembly_gap    7824..7923
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            7991..8500
                     /locus_tag="P5537_06850"
     CDS             7991..8500
                     /locus_tag="P5537_06850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77796.1"
                     /translation="MSKKHKKAHRRGDRGMQGGQGAGGPMYQGQYGQYGQYGMGGMGA
                     DPAAGPYAAETAFAQGAGAGYGPGAGAWPGGVQAGLQAGLGAAGLDGGLLQGMPAFLR
                     TRNSEQFLLGALIGAAAAWVLSDEELRGKIVKSAMKLYAGVAGGFEEMKEQMADIRAE
                     VEAEQHGDA"
     gene            8497..10635
                     /locus_tag="P5537_06855"
     CDS             8497..10635
                     /locus_tag="P5537_06855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HRV77797.1"
                     /translation="MMSGGWVSALEPVHATRGRVRWRYACRPGAPADPHALERAVATV
                     AGVRKARTNAAARALVVEFDAAQTSAERIALDILRMVPAQARKAGARNGEPSVAPVAL
                     SAATLLATRSLQPGLQAPVAFGTAIPLLGEAADDFLEKGVTSHVLEAMAVAISIGRRD
                     YLAANTTSFLLALGEYLESSIERRSDDLLKHLLKPAVDEIWVERDGAEIQIEAAEVRV
                     GDTVIAATGSVIAVDGTVLGGEAMVNEATMTGESVPVARRRGDAVLSGTLVQEGRLRI
                     YAEKVGAQAAAARIADFVEQSLAVKSTTQLEASRMADRLVPMVLGLAGATWLVSRDWE
                     RVAAVLQADYSCALKLSTPVAFKSAMYAAGKSGMLVKGAKALERLAEADTFVFDKTGT
                     LSTGKLEVTDSVAFKPGYSPEDLINLAASVEEHYFHPLALAVVEASRRLDSPRHFDHK
                     EVEFIVAHGVASVIDGRRIVVGSRHFVEDDEGIPVAGHREVIDRLHLEGKTLLYIGFG
                     GELLGVLALRDGLRANSAATIRRLRRLGVKRVLMLTGDHPERARTMAEELGLDDFHAG
                     LLPQDKADILQRLAAQGARIAFVGDGVNDAPALSGAHVGISMHNGADVARLASDLALL
                     EDDIARVADAKALALATRHLIDSNFKLTVGLNTTILSAAAFGLLTPIAASALHNGTTI
                     AILLRALAGAGLPRDRRTGPAATRRGTVSA"
     gene            10632..10883
                     /locus_tag="P5537_06860"
     CDS             10632..10883
                     /locus_tag="P5537_06860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004336577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046914 - transition metal ion binding
                     [Evidence IEA];
                     GO_process: GO:0006811 - monoatomic ion transport
                     [Evidence IEA];
                     GO_process: GO:0055072 - iron ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FeoA family protein"
                     /protein_id="HRV77798.1"
                     /translation="MNSPNRSDAFPLAMAAEGEAVRVVAILGGSGMALRVAELGLNVG
                     SELVVRQRQGGGLVVGRGETRFALGGGMAHKILVARLQG"
     gene            10950..11177
                     /locus_tag="P5537_06865"
     CDS             10950..11177
                     /locus_tag="P5537_06865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046914 - transition metal ion binding
                     [Evidence IEA];
                     GO_process: GO:0006811 - monoatomic ion transport
                     [Evidence IEA];
                     GO_process: GO:0055072 - iron ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FeoA family protein"
                     /protein_id="HRV77799.1"
                     /translation="MMLKQLAVGDRAKVSGFAEAGGPYRRKLLSMGLTPGAELEVVRV
                     APMGDPVEIRVRGFALTLRKGEADALNVDKL"
     gene            11177..13519
                     /gene="feoB"
                     /locus_tag="P5537_06870"
     CDS             11177..13519
                     /gene="feoB"
                     /locus_tag="P5537_06870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(2+) transporter permease subunit FeoB"
                     /protein_id="HRV77800.1"
                     /translation="MKIPAMKNEHLIALVGNPNCGKTTLFNALTGSRQRVGNWPGVTV
                     EKKSGEYRHDGLRFEVVDLPGTYSLDVVDREVSLDESVARDYVHGNEAELVVNIVDAA
                     NLERNLYLTTQLVEMRVPLLVVLNMVDVAQDKGLAIDVEALAHRLGCPVVPVVASEGR
                     GVDALKAAILAAVKVRKPASARVDYQAALEQAVAALVPRLESAAQTAGTSARWLAVRL
                     LEGDDLALGAAGADTAAEAKRLAGELGDDIDIMVADARYGLANRVASAAVTVSGRAGR
                     DLTDRIDRVVLNRALGVPIFLLMMYLMFLFTISIGGAFIDFFDQFAGALLVDGVAAVL
                     TGLGSPEWLTVLLAQGIGGGIQVVATFIPVVGFLFLFLSVLEDSGYMARAAFVMDRFM
                     RWVGLPGKSFVPLIVGFGCNVPAIMATRTLEHRRDRLMTIAMAPFMSCGARLPVYVLF
                     AAAFFPSGAQNVVFGLYLIGIAVAVMTGLVLRNTLLKGEPTPFIMELPPYHLPTVRGV
                     LRHASERLMAFIVRAGRVIVPMVLVLNVLNSVGTDGSYGNEDSESSVLAEIGRSITPA
                     FAPMGLTEENWPAAVGIFTGVLAKEAVVGTLDAAYTALAAEDAGEAGAEEVAFSLADS
                     LVAAFATIPVNLADALGAWADPIGLDVGDLSDQAAVAEEQEVSTGTFGAMAARFDGAA
                     GAFAYLLFILLYAPCTAAIAAIYQESGARWAAFVTAWTTGLGWGVATVYYQAATWAQH
                     PSSSFGWIAAVGACLLLALWALRRYGAREADGRLPLPQQA"
     gene            13530..13766
                     /locus_tag="P5537_06875"
     CDS             13530..13766
                     /locus_tag="P5537_06875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004374161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoC-like transcriptional regulator"
                     /protein_id="HRV77801.1"
                     /translation="MILSRLSDYLRERRRANLADMAIGLDSSVSALEPMLATLERKGR
                     VRRVPAAAGCGTSCCKCDPASTVVFEWAGDAPAS"
     gene            13786..14352
                     /locus_tag="P5537_06880"
     CDS             13786..14352
                     /locus_tag="P5537_06880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004374160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77802.1"
                     /translation="MPGTRTLLVIGIHREELAFGRDVVQGLEVEDLDVLEIPEGLSGR
                     RPLPDETFRYGALHRALYLQLLPYVGGTHRLLIDLHSGLDQQGPSADLLCADTALRAR
                     LRRALDAEGCKERPDASVRIVPLGQAGVVQARTVIPEAIWNNPAFAYLGMELYLPVTV
                     EGRASGAILARRLVRLVTGCMQERGDEP"
     gene            complement(14375..14800)
                     /locus_tag="P5537_06885"
     CDS             complement(14375..14800)
                     /locus_tag="P5537_06885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004336567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77803.1"
                     /translation="MTRIASSSPGRIRVKDPALRGRDCLSRVHKELAPLEGVRELRPN
                     LVAGSIVVFFDHGEVSPAKLEQRIEQALDAALAAPRKARRSIHNRVNRAAKIGMLGSL
                     GASLALAATGNKRWHAVTGGVFVACLGVHLGLHRKALLR"
     gene            complement(14936..16114)
                     /locus_tag="P5537_06890"
     CDS             complement(14936..16114)
                     /locus_tag="P5537_06890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004307531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1513 domain-containing protein"
                     /protein_id="HRV77804.1"
                     /translation="MNKRDFLRTLGGGLSLALLPRHLLAATTPGEFPEIRLIAAWRSL
                     HDLGRDGAARGAKAEGTTDYVGILVPDWQQGVARIETAIAVPDRVHGLLPDRDGGFLV
                     CANRPGPWLMRCAADGEVLARQVLEDEKSGRTLNGHAVFDPAGEWLYTTESETGSTQG
                     WIAVRRRDSLRKEAEFPTRGIEPHELLFDAEGKLVVANGGILRAAGDRKRDLDRMDSS
                     LVRLDPQSGERLGQWWLKDKRLSVRHLALGAVPVAGGRTLVGVALQAEHDDAAERAAA
                     PILAVWNGETLQIPSRETVGAGYCGDIAIGMDGGFYLSAERSNRVTRWHPAAPERLEV
                     IAELNKAGALAEVALDGTHASLIGSPRGLGFWHPQRDPVLLRWPVEIAPDNHWTVVKA
                     "
     gene            complement(16174..18345)
                     /locus_tag="P5537_06895"
     CDS             complement(16174..18345)
                     /locus_tag="P5537_06895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004374157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_function: GO:0015343 - siderophore-iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent siderophore receptor"
                     /protein_id="HRV77805.1"
                     /translation="MKAAVRSGAARPAHAPTRPLLPLSAIMLAVLSAGAQAQATPSSA
                     KTLPTVTVNAAEDAAPQDGHRATATRVGKVLQDPHDIPQAVTTVTNTLMEEQQVGSLK
                     EALRNVSGLSFNAAEGGRSGDNMNLRGFYTFGDMYLDGIRDTAQYNRETFNLEQIDVL
                     RGSAAMLFGRGQAGGVINQVTKTPLLGNRGRITGSVGIDDYREVTGDFNKELGDSTAV
                     RLNVMKRDEGSWRSNPADGAEPEIHREGVGLSLVTGLFTDNEFTFNHYYLKTRDNPDY
                     GISFDPATKRPTKDFSADTFWGTNNTFDDSDTSMTSLVHQHKLSSQAEIRTQLRHASY
                     ERVYWAQAPNRTAAPSFDGSTGSPKVRQTETENLTLQSDLTARADLFGMKHELLAGVE
                     YLKEDSSRRSLQDLDPGAGRFYRPGAFTSAPAITYEGDTLAFYAQDTIEFIPDWKLTL
                     GARHDSLDAEYSSLNSPQLDFSETSLRTGLSWHPTEYTHYYISYSDSFSPTADLYQLS
                     GGSFPAERSKVTELGAKWMLMEGDLALRAALYRADKEWERNTDLESSAAILTRKRRTD
                     GLELEVAGRVTPNWEVFSGFSVMDAEILEAAPGADPRLEGQRPRNTPKLTFNLWSTYA
                     LGGGWKIGGGVEAKSDRYAYVPTAANANSNFIDGKFTPNAAPGYARWDAMLAYEQKSW
                     AARLNVKNIFDRVYYDAVYDQGGFAIPGTGRAIILTGEYKF"
     gene            complement(18570..19955)
                     /locus_tag="P5537_06900"
     CDS             complement(18570..19955)
                     /locus_tag="P5537_06900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux transporter outer membrane subunit"
                     /protein_id="HRV77806.1"
                     /translation="MLRSRLRSRLLPLLTALLAAGCAITEPVARPDQPLPDAWAETAP
                     AEGAAVDAAWWQGFGSARLDALVAEAMAAAPDLRIQAERVVQAELALRQAGASLLPAL
                     NLGGGSATRNVGGNESGSTDLSLGASYELDLWGRIAAGVDASRASLAATRHDYDAARL
                     SLSASVATTWFQSLALQERVEIARQNLAIAEGVLRVVQARYDNGAASALELSQQRSTV
                     LNQRKAIEPLEVQLRQTRSALAILLGRNPQDGIAGDERLEALQVPGIDAGLPSELLLR
                     RPDLAASEARLAAAAANVAAARAALLPGIDLAAGAGVGSAALLSLADTTRTLSLSASV
                     VQKIFDGGRLRAEVEVQRSRQRELLEAHRRAILVALKEVEDALADGLRDANQEAAQRE
                     ILAEARRSLRLAELRYREGADGLLTVLDAQRTLFSAQDQLAQLRLARLGDAVNLYKAL
                     GGGWGAGRPAD"
     gene            complement(20081..22108)
                     /locus_tag="P5537_06905"
     CDS             complement(20081..22108)
                     /locus_tag="P5537_06905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MacB family efflux pump subunit"
                     /protein_id="HRV77807.1"
                     /translation="MKVERLPGEGARPSSDPPAAATATRAAPRVASSTAAPLIELRGI
                     TRSFVNGEVETRVLHGIDLTIHAGEFVAIMGASGSGKSTLMNILGCLDRPSGGTYRFM
                     GEDVAALDRDALARLRREAFGFVFQSYNLLGGATARDNVEVPAVYSGMPREERHARAE
                     ELLARLGLGERIHHRPGQLSGGQQQRVSIARALMNGGRIIFADEPTGALDSRSGAEVM
                     KLLAELSSAGHTIVLITHEREVAEQAQRIIEIRDGRIVADPGPRPPQVPEPDFAPHVD
                     RTSPLSDVVEATRTALRALRANLFRTILTLLGIVIGVASVIAMLAIGDGAKQKVIDQV
                     SAMGTNLLTVRPGAPNTRGRDAPATLVIEDVQAIAELPNVLASVPEQGATITLRAGNL
                     DHRSSVNGTSADYVVARNWAPASGTFFSAEDEARYATVAVLGQTVARALFPGRDAVGE
                     FILVNNIPFQVMGVMTPKGATPWGQDQDDIVFMPFTTASLRITGQRFLRNVTVAVEDV
                     GQIDDTQAAVQSLLLARHGVEDFQIRNMASVIDTVSETQNTLTVLLGTVAAISLLVGG
                     IGVMNIMLVSVTERTREIGIRMATGARTRNILQQFLIEALVVSAVGGLIGVAVGLGAA
                     AIIEAFGTAVQYSLTPVVLAFSCAFLTGLVFGYLPARKAARLDPVVALASE"
     gene            complement(22105..23433)
                     /locus_tag="P5537_06910"
     CDS             complement(22105..23433)
                     /locus_tag="P5537_06910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HRV77808.1"
                     /translation="MNDDKPSTRTARPRWGRRAVLILVPLLLAGGWYGRSAFLGERDA
                     ATNYQFSAVQRGDIEDVVTATGTLQPRDYVDVGAQVSGQLRKIHVEVGDTVEAGQLLA
                     EIDPTVYRARVDASRAQLRNLRAQLQDREAQLALAQIQLRRQRALMAEDATTKESLQT
                     AEASAKSAAAQLDALRAQIEQIESTLRADEANLQYARILSPMAGTVVSISARQGQTLN
                     TNQQAPVVMRIADLSTMTVQTQVSEADIGRVKLGMEAYFTTLGGSGKRWHGKLEKVEP
                     TPTVTNNVVLYNALFDVPNPDGRLMTQMTAQVFFVVAQAKDALLIPMAALAQGQARAP
                     QAGGAAAPAAAPPPGTAQPAGNGGPGRGGGMGAGQGRGLTPGATGAAPRSGTVRVADA
                     RGALEERKVELGVSNRVQAQVLSGLAEGERVVSGLVVGNGTGRPQMTPRL"
     gene            23720..24721
                     /locus_tag="P5537_06915"
     CDS             23720..24721
                     /locus_tag="P5537_06915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome-c peroxidase"
                     /protein_id="HRV77809.1"
                     /translation="MMKLKATSVAVALVVAGSAWAASTVRDELIKPIEPAKVDNAAKV
                     ELGKKLWFEPRLSMSGIISCNTCHNLSMGGTDNLKTSIGHGWKAGPVNSPTVYNSSLA
                     IAQFWDGRAADLKEQAGGPIQADVEMNMPHTLAIGILQSIPGYVAEFKSVYGKDKIDI
                     DMITDSIAEFEKTLVTPDSRFDKWLKGDDKALSEKELAGYTLFKESGCVACHNGPAAG
                     GTSFQRMGVVEPYKSSSPAEGRSAVTGADADRFNFKVPTLRNVELTYPYFHDGEAATL
                     EQAVDTMGRLQLGRTYSKDEIGQIVAFLKTLTGELPQIAMPILPPSSNETPRPDPFK"
     gene            24894..25319
                     /locus_tag="P5537_06920"
     CDS             24894..25319
                     /locus_tag="P5537_06920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004380757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HRV77810.1"
                     /translation="MMNTCTYASSDAIACLRQAGIPVTHQRIEIARALFSAPVHLSAD
                     QIWAKVLDASPDVSRATVYNTLRLFSEKKMIRELFVDPQRVVYDSTTTPHHHLYNIDT
                     GEVRDISDDELRVIGEPRLPAGVVLDEIDVIVRVRNRVA"
     gene            complement(25425..25841)
                     /locus_tag="P5537_06925"
     CDS             complement(25425..25841)
                     /locus_tag="P5537_06925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biopolymer transporter ExbD"
                     /protein_id="HRV77811.1"
                     /translation="MAFGGFSQGETRAPQSDINMVPLIDVMLVLLIVFMITAPLLTHS
                     VKIDLPQASSAPTEQKPETVALSIDGDGRVFWNNEAVDEVALPARLAAAAAQKPQPEL
                     HLRADRNTRYEVIADVMAQARSAGIEKMGFVTVPER"
     gene            complement(25841..26602)
                     /locus_tag="P5537_06930"
     CDS             complement(25841..26602)
                     /locus_tag="P5537_06930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004380753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HRV77812.1"
                     /translation="MDSSQAFGLAHLWAQSDNIIRAVALILLVMSITSWYLILSRALR
                     QLRARGHNGAVEAFWAAPDLDAGLRVLAERAPESPVEALAQQGAAAAQHLRRHTHGNT
                     LGGTLDGDEVITRALRKSIALSTAALESGLTMLASIGSTAPFVGLFGTVWGIYHALVN
                     ISVSGMATLDKVAGPVGEALIMTAFGLFVAIPAVLAYNAITRANRVELSELDAFAHDL
                     HAWFATGSRIAAVAGAAPRAAEVAAGTPAAAHGAA"
     gene            complement(26605..27345)
                     /locus_tag="P5537_06935"
     CDS             complement(26605..27345)
                     /locus_tag="P5537_06935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0031992 - energy transducer activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy transducer TonB"
                     /protein_id="HRV77813.1"
                     /translation="MHAARGLGSSPLRRSILLGLVVAAHLGGAALLARLADERPLPAE
                     LIPIQVALIEAPAAVEPAPAPPPEPVVEPPRPPEPEPPPVVRPPEPAPPPPPKPVVKK
                     PTPKPVVKKPAPVTESPTALSAAEDAAPPPPPAPAPPAAAAAATAAPATVTAARFDAA
                     YLNNPRPGYPALSRRLREEGQVTLRVLVSPDGQPAQVELRTSSGSDRLDRAAREAVAR
                     WRFVPARRGDTAIESWVLVPIVFKLQGN"
     gene            complement(27541..28020)
                     /gene="bfr"
                     /locus_tag="P5537_06940"
     CDS             complement(27541..28020)
                     /gene="bfr"
                     /locus_tag="P5537_06940"
                     /EC_number="1.16.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004322 - ferroxidase activity [Evidence
                     IEA];
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA];
                     GO_process: GO:0006880 - intracellular sequestering of
                     iron ion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin"
                     /protein_id="HRV77814.1"
                     /translation="MKGDKKVIQYLNKQLTIELTAINQYFLHARMYKNWGFERLGKHE
                     YDESIEEMKHADMLIERVLFLEGLPNLQNLNKLLIGENVPECMQGDLKLELGGRENLV
                     EAIAYCESCKDYVSRELFEHILEDTEEHIDYLETQLGLVDSVGLQNYLQSQMEPSAS"
     gene            complement(28017..28256)
                     /locus_tag="P5537_06945"
     CDS             complement(28017..28256)
                     /locus_tag="P5537_06945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HRV77815.1"
                     /translation="MYVCVCNAVTERQIHHAAAQGARTLRDLRQSLGVTAECGRCARC
                     AHDCLRSAVIPAPRTGMTGLLAGISPAFTVSLEST"
     gene            complement(28307..28438)
                     /locus_tag="P5537_06950"
     CDS             complement(28307..28438)
                     /locus_tag="P5537_06950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemin uptake protein HemP"
                     /protein_id="HRV77816.1"
                     /translation="MAPPRFLLTSKELLGERREVRIEHEGSEYVLRATRNGKLILTK"
     gene            complement(28605..29009)
                     /locus_tag="P5537_06955"
     CDS             complement(28605..29009)
                     /locus_tag="P5537_06955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77817.1"
                     /translation="MLLVALSFGQAARAQGVVLVSARAGGIPELDRETAAQLYLGRRT
                     SLPDGRSARLLDLPAGPERDLFYERLTAKNPSQIRAYWSRMVFTGRAHPPHEANDQED
                     ALRRVLTDPSALAYLPAASVVGQPLNVLLRLE"
     gene            complement(29047..30243)
                     /locus_tag="P5537_06960"
     CDS             complement(29047..30243)
                     /locus_tag="P5537_06960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77818.1"
                     /translation="MHRAVTLLASIAALAGGIDPATASDLQVSGFATLGAAYTRSDEL
                     EFARVGIDAPGGNRVDTGPDSVLGLQFGWQAGNGSGAVLQLVTRETQRGDYTPRPALA
                     FLSHSLNPALTVRAGRLRSPFFMLSDTADINYSQPWVRPPVEVYGLNPFTDMDGVDLL
                     YRSRLGDSFIELHPYFGTSRIPVIGGGRGHLRRLRGLTATLERDEFSFSASHAEAELS
                     VIRTSQSYQDLVESWNIPPALQARLSGKGAHASFSSLGMQWDDGRWRVIAELARMKAS
                     AFTNSATGAYVSVGRRFGALMPYVGLARQRQDEPIADPALANSDMSANALAAFNRSRN
                     QAQRSITVGTRWDLTPHAALKAEFSHIDTSRDAHGTFIARGDPFAPGLDDRNINLLSV
                     SVDVVF"
BASE COUNT         4450 a         9846 c        10911 g         4863 t
ORIGIN      
        1 gcgatcactc gatcgcggag gccgacttgg ccatctcgcg cagggcgaac ttctggatct
       61 tgccggtcga ggtcttgggc agcacgcaga actcgatgaa cttgggcacc ttgtagcgcg
      121 ccaggtgttc gcggcagtgc gcgatgatgt cgtcggcggt cacgccagcg ccttccttga
      181 cctcgatgta ggccgccggc acctcgcccc acttctcgtc gggcttggcg accaccgccg
      241 cggtcagcac cgccgggtgg cggtacagca cctcttccac ctcgagcgag gagatgttct
      301 cgccgccgga gatgatcacg tccttggagc ggtccttgat cttgacgtag ccgtccgggt
      361 gcatgaccgc gaggtcgccg gtgtggaacc agccgccggc gaaggactcc tgggtggcct
      421 tctcgttctt gaggtagccc ttcatcacca ggttgccgcg gaacatgatc tcgcccatgg
      481 tctcgccgtc ggcgggcacc ggctccatcg tcaccgggtc gagcacggtg atcgcttcct
      541 gcatgtggta gcgcacgccc tggcggccgt tgcgctcggc gcggcggtcg atcggcagcg
      601 cgtcccactc ggggtgcttg gcgcacaccg aggccgggcc gtaggtttcg gtcaggccat
      661 agacgtgggt gatgtcgaag ccgatgcgtt cggcgccctc gatgatcgcg gccgggggcg
      721 cggcgccggc gatgaggccg gccacactgt gctcgatgcc ggcgcgcagg ccgtcgggcg
      781 cgttgatgag catgccgtag acgatcggcg cgccgcacat gtgggtgacc ttgtggcggc
      841 ggatcagctc gtagatcagc gccgggtcga ccttgcgcag gcagacgttg atgccggcgt
      901 tggccgccat ggtccacggg aagcaccagc cgttgcagtg gaacatcggc agcgtccaca
      961 ggtaggacga atgctgcggc atgccccagc tgatgatgtt ggaggcggca ttgagatacg
     1021 cgccgcgatg gtggtagacc acgcccttcg ggttgccggt ggtgccggag gtgtagttga
     1081 gcgcgatcgc gtcccactcg tccgcgggca gcttccactg gaagtcgggg ttgccgccgg
     1141 cgaggaagtc ctcgtacagc agcgtaccga cgcgctcctc gcccggatac tcggggtcga
     1201 gcgcgtcgat caccaggggc ttgtcgcccg gcagcagttc gagcgcggca cggaccacgc
     1261 cggcgaactc ggggtcggtg atcagcacct tggcttcgcc gtgctgcagc atgaaggcga
     1321 tggcgtcggc gtcgaggcgc gtgttgagcg tgttgaggac cgcgccggtc atcggcacgc
     1381 cgaaatgcgc ctcgaacatc ggcggcacgt tgggcagcat gcacgcgacc gtgtcgccct
     1441 tcttcacgcc gtgcgcgacc agggcgctcg ccagccggcg gcagcgctcg taggtctggc
     1501 tccaggtgta ggcgagcgtg ccatggacga cgctggtgcg cgtcggatag accatggcgg
     1561 tgcgctcgat gaagctcagc ggcgacagcg gcacgtagtt ggccgcgttc ttgtcgagac
     1621 cttgctggta tgcgttttgc gacatccttt tcctctcccg ttcgttcgaa aacagactgg
     1681 tcgggccggc gtcccgcgcg gggttcggtc cataccgtat agtatggagg atggcgtcga
     1741 tcttgtctgc agttcccctg tgcgcaaggc ctgcgaaggc agggtgaagc gctcaggcgg
     1801 gctgcaccca gatgtggcgc gacaccgcgt gctcgatcgc gagctcgacg tgctcgcaca
     1861 atagcaccgt catcggctgc tgttgcagca ccttcaccgc gtgcgcggcg gacagcccgt
     1921 aggcatggag ctgctcgcgc tgcagtgggt cgatctcgtc gccgaagtcg tcgatccgca
     1981 ccatgcgccc gaccggggtg ccgatcaggc ggatgcgctc gtggggttgc gggatgggct
     2041 tggagtgggt ggcgttcatg gcgcggactc ctcagaagat caggcgcagg ccgtggttga
     2101 gcaggccgcc gatcaggaag gcggtgggga tgatcatcgc cagcatcagt gcggcgacct
     2161 tcatgccctg ctccttgatg atcatcatca ggctggcgat gcagggcacg aagagcgtga
     2221 tcgtgaccat gccgaccacg gcctggatca tcgacagctc gctctgcagc gcgaacaggc
     2281 cgctggcgcc gaagtcgcgg cgcaggaagc ccatcacgaa ggcggcgctc gcctccggcg
     2341 gcaggccgag ccagcccacc accagcggct cgcccgcctc gatgatccac ggcaaggcgc
     2401 cgctgcggtc gaggccgaac atgatcaggg tgccgatcag gaacagcggg atgacctcga
     2461 tcaggtacca cttcagccgc ccgccggtct tcttgagcac gttgcccagt acaggcatgc
     2521 gcatcggcgg caactcggtg acgagcggca cgcgccggcc gggcacgacc ttgctcgcca
     2581 gccagccggt gaacagcagc acgccgacga tcgccagcac ccagatcacc gtagcaccga
     2641 acgagatgcc gccgagcagg ccgagcacca cgccgagctg cgccgagcac ggaatcgcca
     2701 gcgccatcag gtagatcgtg atcaggcgct cgcgcggggt gtgcaggatg cgggtggtga
     2761 gcgtggccat ggtcacgcag cccagcccga gcaccatcgg cagcaccgcg cggccgttga
     2821 ggccgatggc ggcgaacatg cggttggcga tcaccgacag gcgggagaag tagccggagt
     2881 cttccagcac gccgaaggcg aggaagaagg tggtgacgat gggcaggatc agcgccagcg
     2941 cgtaggtcat gcccatggtc cacaggccgt attcgccgac gatgaggtcg gccagccagg
     3001 gcgtggagac gtggcgggtg acgaagtcgg tgaccgccgg gttgagcacc tcgccgaaga
     3061 agtcttcttc gagcagcccg accagggtgc tggcgccgaa gtcgcccacg aagagataca
     3121 ccagatagag cacgccgagc agcatcggcc agccccacag ccggtgcacc gcgacgcggc
     3181 cgagcagcat cgacagcgta cggtccttgc cggcggcctg gcgggtgacg gtgcgcgcga
     3241 gcgcctcggc cgcgccgccg cgctcgcgcg cgagnnnnnn nnnnnnnnnn nnnnnnnnnn
     3301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3361 nnnnnnnnnn nnnngtgcgg cgcaggttct tggcgtcgcc gacctggatc agcgtgcgca
     3421 tgtcctcatg gagcagcgcg cgcatggtgg cgcgctcgtc gtcgctgcgc gagggcaggg
     3481 cgagcacgcc cggggtgtcg agcagcgagg cctcgcggtc gaagcgcggc gtcgcacgcg
     3541 agacctcgac cgtggttccg gggtagttgg acaccgtgac gtaggtgccg gtgaggcggt
     3601 ggaacagcac cgacttgccg acgttggggt ggccgacgag ggccagggtg cgcagcacgg
     3661 cggcggtggc gggggcgggc gaagtggcgc agtccatgaa cgcgggtgtc cggagggcgg
     3721 ggtaagccta gaacggtaat gggtcgcatt atgactttta ctgatctagc tcaaatgtcc
     3781 tgcgaagggc gcgcatttca tggcctcggt gcgcttgaca ggcgccggga ttttaacgat
     3841 attgcgaatc attcgcaaaa cgaagaggac ttgctcgtgc tttctgctcg ctcgagcggg
     3901 cagggcctct tcaccggacc gactgaagga gaacgacttg tcccgttaca ccggcccccg
     3961 cctgaaagtg atgcgcgccc tcggcaccga gttgccgggc ctctcgcgca agccgctggg
     4021 cgagcgcaac tatccgcccg ggcagcacgg ccagcgcccg aagcgcaagt ccggcttcgg
     4081 cgtgcagctg atcgagaagc agaagctgcg cttcaactac ggtctcggcg agaagcagat
     4141 ccagcgcctg ttccgcgagg ccaagcgcga ccgcggaccg accggcgaca agttgctgga
     4201 gctgctcgaa cgccgcctcg acaacttcgt gttccgcgcc ggctttgcgc cgactgcggt
     4261 ggcggcgcgc cagctcgtgc gccacaagca cgtgctgctc aacgggcggg cggtgaacat
     4321 cccctccatc cgcatccgcc cgggcgatcg catccaggtc accgagcgcg cgcgcagcat
     4381 cccggtggtg gtggagtcgc tcgccgagcc ggcgcttgcc cgccccgaat ggcttgtctt
     4441 cgacgaggcg gctctggcgg cgacggttac gcggactcct gcgcccgacg aggtcccgtt
     4501 cccggtcgac gtccagcagg tcgtcgagta ctacgcggtg cggttgtgag cgcgcaggcg
     4561 tcggccaact ggcgcagcgg cgcggcgacc gaggggcccg agtacgacac cgatcccgag
     4621 ctcgcgctgg cggccgtgct gcagttgctg tcgcgctttc cggcacggcg atcgccggcc
     4681 ctggcgcagg cgatcgccag tcattttcgc gtgatcggca gcgatccccg cctctccgcg
     4741 tgcttgcgcg actgcgccgc ccggctcgtc cgagactggg aggcctatgc ggtgctcggc
     4801 gaggccggtg acctcagtca ggattcgcgc gtgctgcact gaacggcgcg cttcggcgcg
     4861 gtccatcttt tcgttttacg aggagaagct catgagcaag aaatgctgca agaaggacaa
     4921 gccctgcaag ggatgtccgc ggcgcgcgaa gtagcccgca atcgctgcgg atgttgacga
     4981 ttatcaaacg agaacgattg tcgttgttgc taacatttgc aaactgcacc acagaagccc
     5041 gatgacggaa atcatccatt gcaccagggc tgctgccgga cacaaggaga gcccccaatg
     5101 aagcgtctga tcctcgccgc cacgctggcc ctcgccccgc ttgcctcgcc cgcgtgggcc
     5161 tcgggtgcgg gcgagcgcag cgcccacttc gagggcaagc cgtccgcaac cctggcgcag
     5221 gcggtggcca acttcagcga gtacaacctc aagctgaacg ccattctcga tggcaaggtc
     5281 accgacgccg acatggccga ggtgcaccaa ctcacctaca cgctcgagaa cgcgctcaag
     5341 aagatcaacg aggagatgag cgcgctcgcc ggcacgctcg aagaggtgca cctcgcttca
     5401 gagaagctgg atcgtgacgc ggtgctcaag catggccgcg cctacctttc ggtctccggc
     5461 caggtcgtca ggtaagaagt ccgccgggcg catgcccggt ggagcgaggc gcgagcgtcg
     5521 gctgttccgg tcgcgtcgat ggcgccggtt ccggccggcg accgtcccgt agcgccggtc
     5581 gtccgggttc ctcatccttt tcgggctgct ccagcgggcg gcccttcttt gtccacctct
     5641 ccctgtaaag gaatcgtcat gtctcatcgc aagtccgggc tgcgcccgat cgtgctggct
     5701 tcgctgttcg ccttctgctc cgccccggct ttcgccgagc ggccgatggc ggtcgatgat
     5761 gccggcacgc tcgagcgcgg cggtgccaag ctcgagttcg gctggagccg cgacgatgcc
     5821 gtgcgcggtt acgagggcgc ggccggtttt ggtccgatcg acgatgtcga ggtggaggtg
     5881 ggcttcgggc gcgcgaagga tcgcgacgcc gaccccgacg cgaagatccg cgccgtcggt
     5941 gcggcgatca aatgggggcc gctgcagtcc gagaccgggc tgtccgccgg gctgaagtac
     6001 gaatatggcc gcgagcgcgt cagcggcgag ggttcttcgc gtgtcgacgc gctcgccggc
     6061 ctggcaacgt gggcattcga gcaggggccg cgggtgcatg tgaacctcgg ccgcgagtgg
     6121 gcacgcgacg acgaagacct gaacttctgg ggtgtcggcc tcgacgtgcc gctcaccgag
     6181 cgactcgact tcgtggtcga gaccttcggt gcggaacatg ccggcccgga tcgccaggtc
     6241 ggcctgcgct acacgatcgc cgacggtgtg aagatctccg gtgcggtcgg ccgcggcaac
     6301 gatcgcaaca tcgccaacgt cggggtggcc tgggagttct gagcgagcgg cgcgctcgac
     6361 gaggggaaag ttcgatggtt tcgttcaagg agttgcgcgg cttcctgcgc gacgtgcgca
     6421 tcgcccacca catccgcggg cggatccggc tcaagctcga cggtcgaggc ggcgcgatcg
     6481 acttgcccaa ggtcgaggca ggcgcctttc aatccctgct cgaccgcacg ccgggcgtgc
     6541 gctcggtgca ggtgaacctg ctcgcgcgct cgtgcaccgt ccattacgac cccgaggtga
     6601 tccccgagca cgcgtggggg gattttctcg ctggtgcagc ctccgaggct gcggccgtcc
     6661 tcgagcgcat cctgcacgac agctaccggg agatcggcaa tgcagaacta cgatgagttc
     6721 atcctgcgcg cgcaacgcat cgacccgcgc gcaccttatc cggtggtgca ccaggcggtg
     6781 cggatcgcgc tgtacgacga gtacgccgcg cgcagcttct atgcgcgcgt ggccgaagcc
     6841 ttcggcgcac gtcctccctt cgccaacatc gtccgttccg aggaacaaca catcgcggtc
     6901 ttgctcgggc tgtgcgagcg cttcggcatc ccgcgcccgc tcgatccctt cccgcaggaa
     6961 accaccgtcg caccgacctg gctcgccaat tgccagcgtg cggtcaatgg cgacatcgcc
     7021 aacgtccgct tgtacgcgta cctgctgacc caggtggcgg agccggaaat ccgtcaggtg
     7081 ttccagcgcc tgcaggcggc ctcgctgcag aaccacctgc ccgcattccg tcaggccgcc
     7141 gccgctgcgc aggcgcagga gaactaccac gctgcccacg gcatcccgcc gcagcaggcc
     7201 tacgtgaggc atgggccgct gtccgacttt ctcgagacgg ccttctcgca actcgggccc
     7261 tacgccgggc cgctcggcct cttcagtccg cttctgcgcc gtgctcaccc cgccatgctg
     7321 gccggcatgg tcacaggggg cgcaggagtc tatctgttga aagacaggat cggccgtcat
     7381 cgcaaggaga actgacatgt tcccgctctt tcccttcgtc gcaggggtgc tgaccggcgc
     7441 cgtcgccctc cgcctcatca agaccgacaa gaccaaggcc gggctggaca aggcgcagga
     7501 caagctgcgt gacgccacgg tgtccagcct ggaggccatc gaacacgctt cggcccgcgc
     7561 ccgcaagcgc ctgaccgctg ccgaggcgga cgaagatggc gagtcgatgc cagcggaggc
     7621 cgccgagcca tccgcacccg cggcgcgcaa gcgtgcgccg cgtgccgcca aggccgcgcc
     7681 caaggtggac gctgccgcag gcaaggagga cgccgagtca tgagaacccc gatcctgccc
     7741 catctgccct ccgcgccgct tgtcacggtg agccgcgccg cgggcggcgg cttcgtccag
     7801 ggtttcgtcg ccgcaggctg cgtnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7921 nnngcagccg gcgtgctgct gatcgaacga ctgctgcgcg attccgcgaa agccgtacag
     7981 gagaggaagg atgtctaaga agcacaagaa agcccatcgc cgtggcgacc gcgggatgca
     8041 gggcgggcag ggcgccggcg ggccgatgta ccagggccag tacgggcaat atggacaata
     8101 cggcatgggc ggcatgggcg cggacccggc tgccggcccg tacgcggcgg agactgcgtt
     8161 cgctcaggga gccggcgcgg gctacggtcc gggcgccggg gcctggccgg gcggcgttca
     8221 ggccggtctt caggccggcc tcggcgcggc cggcctcgat ggtggcctgt tgcagggcat
     8281 gccggccttc ctgcgcacgc gcaacagcga gcagttcctg ctcggcgccc tgatcggcgc
     8341 tgccgcggcc tgggtgctga gcgacgagga actgcgcggc aagatcgtca agtcggcgat
     8401 gaagctttat gccggcgtcg ccggcggctt cgaggagatg aaggagcaga tggccgacat
     8461 ccgcgccgag gtcgaagcgg agcagcacgg agacgcatga tgagcggcgg ctgggtgtcc
     8521 gcgctggagc cggttcatgc gacgcgtggt cgcgtgcgct ggcgctacgc ctgccgcccg
     8581 ggggcgccgg ccgacccaca tgcgctggag cgcgcggtgg cgacggtggc cggtgtgcgc
     8641 aaggcgcgga ccaatgctgc cgcacgcgcg ctggtggtcg agttcgacgc cgcacaaacc
     8701 tccgcggagc gcatcgccct cgacatcctg cgcatggtgc ccgcgcaagc ccgcaaggcg
     8761 ggggcacgca acggcgagcc cagcgtcgcg ccggtcgcgc tgagcgcggc gacgctgctg
     8821 gcgacgcgct cgctgcagcc cggcctgcag gcgccggtgg ccttcggcac ggcgatcccg
     8881 ctgctcggcg aggcggcgga cgacttcctc gagaaaggcg tcacctcgca tgtcctcgag
     8941 gcgatggcgg tggcgatctc gatcgggcgg cgcgattacc tcgccgccaa taccacctcg
     9001 tttttgctcg cgctcggcga gtacctggag tcctcgatcg agcgccgctc cgacgacctg
     9061 ctcaagcacc tgctcaagcc cgcggtcgac gagatctggg tggagcgcga cggtgccgag
     9121 atccagatcg aggctgcgga ggtccgcgtc ggcgacacgg tgatcgccgc caccggttcc
     9181 gtgatcgcgg tcgacggaac ggtgctgggt ggcgaggcca tggtcaacga ggccaccatg
     9241 accggcgaga gcgtgccggt ggcgcgccgg cgtggcgacg cggtgctgtc cggcacgctg
     9301 gtccaggaag gccggctacg catctatgcc gagaaggtcg gcgcgcaggc cgcggcagcc
     9361 cgcatcgcgg atttcgtcga gcagtcgctc gcggtcaaga gcacgaccca gctcgaggcc
     9421 tcgcgcatgg ccgatcgcct ggtgccgatg gtgctgggcc tggcgggtgc gacctggctg
     9481 gtgtcgcgcg actgggaacg cgtcgcggcg gtgctgcagg cggactactc ctgcgcgctc
     9541 aagctgtcga ccccggtcgc cttcaagtcg gcgatgtacg ccgccggcaa gtcgggcatg
     9601 ctggtcaagg gcgccaaggc gctcgagcgc ctggccgagg ccgacacctt cgtattcgac
     9661 aagaccggca ccctgagcac cggcaagctc gaggtgaccg actcggtcgc cttcaagccg
     9721 ggctattcac ccgaggacct gatcaacctg gcggcctcgg tggaggagca ttacttccac
     9781 ccgctggcgc tcgcggtggt cgaggcttcc cggcgcctgg acagcccgcg ccacttcgac
     9841 cacaaggagg tcgagttcat cgtcgcccat ggtgtggcca gcgtcatcga cggccgccgc
     9901 atcgtggtcg gttcgcgcca cttcgtcgag gacgacgagg gcattcccgt ggctgggcat
     9961 cgcgaggtca tcgaccggct ccacctcgag ggcaagacgc tgctctacat cggcttcggt
    10021 ggcgagctgc tcggcgtgct ggcgctgcgc gacggcctgc gcgccaacag cgcggcgacc
    10081 atccgccgcc tgcgccgact cggcgtgaag cgcgtgctga tgctgaccgg agaccatccc
    10141 gagcgggcac gcacgatggc cgaggaactc ggcctcgacg acttccacgc cggcctgctg
    10201 ccgcaggaca aggcggacat cctgcagcgc ctggcggcgc aaggtgcgcg catcgccttc
    10261 gtcggcgacg gcgtcaatga tgcaccggcg ctcagcggcg cccacgtcgg catctcgatg
    10321 cacaacggcg ccgatgtcgc gcggctggcg tcggaccttg cgctgctcga ggacgacatc
    10381 gcccgcgtcg ccgacgccaa ggcgctggcg ctcgccacgc gccacctgat cgacagcaat
    10441 ttcaagctca cggtggggct caacaccacg atcctgtcgg ccgccgcgtt cggcctgctg
    10501 accccgatcg cggcctccgc cctgcacaac ggtacgacga tcgcgatcct gctgcgcgcg
    10561 ctcgccggcg ccggcctgcc gcgcgatcga cgcacggggc cggcggccac ccgacgcggc
    10621 acggtgtccg catgaacagc ccgaaccgtt ccgatgcctt tccgctggcg atggctgccg
    10681 agggcgaagc cgtccgcgtc gttgcgatcc ttggcgggtc gggcatggcg ctgcgcgtcg
    10741 ccgagctcgg cctgaacgtc ggcagcgagc tcgtggtgcg ccagcgccag ggtggcggct
    10801 tggtggtcgg gcgcggcgag acgcgcttcg cgctcggcgg cggcatggcg cacaagatcc
    10861 tcgtggcgcg gctgcagggc tgagccgcga cgctttcgaa ccgtgccggg ccgcttggcc
    10921 cggcattcac gtcagttgga gtaggtcgga tgatgctcaa gcaactcgcg gtcggtgacc
    10981 gcgcgaaggt cagcggcttt gccgaggcgg gcggtcctta ccgtcgcaag ctcctgtcca
    11041 tggggctcac gccgggggcc gaactggagg tcgtgcgcgt ggcgccgatg ggcgacccgg
    11101 tggagatccg cgtgcgcggc ttcgcgctca ccctgcgcaa gggcgaagcc gatgccctga
    11161 acgtcgacaa gctgtgatga agatccctgc aatgaagaac gaacacctca tcgccctggt
    11221 gggcaacccg aactgcggca agaccaccct gttcaacgcc ctcaccggct cgcgccagcg
    11281 cgtgggcaac tggcccggcg tcacggtcga gaagaagagc ggcgaatacc gtcacgacgg
    11341 cctgcgcttc gaggtcgtag atctgcccgg cacctactcg ctggacgtcg tcgaccgcga
    11401 ggtctcgctc gacgagagcg tcgcgcgcga ctacgtccat ggcaacgagg ccgagctcgt
    11461 cgtcaatatc gtcgatgcgg ccaacctcga gcgcaacctg tacctcacca cccagctcgt
    11521 cgagatgcgg gtgccgctgc tggtggtgct caacatggtc gacgtggccc aggacaaggg
    11581 gctcgcgatc gacgtcgagg cgctggcgca caggctcggt tgcccggtgg tcccggtggt
    11641 ggcgtccgag gggcgcggcg tcgatgcgct caaggcggca atcctcgccg cggtgaaggt
    11701 gcgcaagccg gccagtgccc gcgtggacta ccaggcggcg ctcgagcagg cggtcgccgc
    11761 gcttgtgccg cggctcgagt cggccgcgca gacggcgggg acgtcggccc gctggctggc
    11821 cgtgcgcctg ctcgagggcg acgacctcgc gctaggcgcc gcgggcgccg acaccgcggc
    11881 cgaggcgaag cggctcgcgg gcgagctcgg cgacgacatc gacatcatgg tggcggacgc
    11941 gcgctacggg cttgccaacc gcgtcgcctc ggccgcggtc acggtgagcg gccgcgccgg
    12001 tcgcgacctc accgaccgca tcgaccgtgt cgtgctcaac cgggcactgg gcgtgccgat
    12061 cttcctgctg atgatgtatc tgatgttcct gttcaccatc agcatcggcg gcgccttcat
    12121 cgacttcttc gaccagttcg ccggggcgct gctggtcgat ggcgtggccg cggtgctcac
    12181 cggcctcggt tcgcccgagt ggctgacggt gctgctggcg cagggcatcg gcggcggcat
    12241 ccaggtcgtc gccaccttca tcccggtggt cggcttcctg ttcctgttcc tgtcggtgct
    12301 ggaggactcg ggctacatgg cgcgcgcggc cttcgtcatg gaccgtttca tgcgttgggt
    12361 gggcctgccc ggcaagtcct tcgtgccgct gatcgtcggt ttcggctgca atgtgccggc
    12421 gatcatggcg acacgaacgc tcgagcatcg tcgcgaccgc ctgatgacga tcgcgatggc
    12481 gcccttcatg tcctgcggcg cgcgtctgcc agtgtatgtg ctgtttgctg ccgccttctt
    12541 cccgtccggg gcgcagaacg tggtgttcgg gctctatctg atcggcatcg cggtggcggt
    12601 gatgaccggc ctggtgctgc gcaacaccct gctcaagggc gagccgaccc ccttcatcat
    12661 ggagctgccg ccctaccacc tgcccacggt gcggggcgtg ctgcgccatg cgtcggagcg
    12721 cctgatggcc ttcatcgtgc gcgccggccg ggtgatcgtg ccgatggtgc tggtgctcaa
    12781 tgtgctcaac tcggtcggca ccgacggtag ctacggcaac gaggacagcg agtcctcggt
    12841 gctcgccgag atcggccgca gcatcacccc ggcgttcgca ccgatgggcc tgaccgagga
    12901 gaactggccg gccgcggtcg ggatcttcac cggcgtgctc gccaaggagg cggtggtcgg
    12961 cacgctggat gccgcctaca ccgcgcttgc ggccgaggac gccggcgagg cgggcgccga
    13021 ggaggtcgcc ttcagccttg ccgacagcct tgtcgcggcc ttcgccacca tcccggtgaa
    13081 ccttgccgat gcgctcggcg cgtgggcgga cccgatcggg ctggacgtcg gtgacctcag
    13141 cgaccaggcc gcggtggccg aggagcagga agtctcgacc ggcaccttcg gcgccatggc
    13201 ggcgcgcttc gacggggcgg ccggcgcctt cgcctacctg cttttcatcc tgctctacgc
    13261 gccatgcacc gcggcgatcg cggcgatcta ccaggagtcg ggtgcgcgct gggccgcctt
    13321 cgtcaccgca tggaccaccg gcctgggctg gggcgtggct accgtgtatt accaggccgc
    13381 gacatgggca cagcatccga gctcgtcctt cggctggatc gcggcggtgg gcgcgtgcct
    13441 gttgcttgca ctgtgggcgc tgcgacgcta tggcgcgcgc gaggcggacg gccgcctgcc
    13501 gctgccgcag caggcctgag gcggcggcga tgatcctgtc ccgcctgagc gactacctgc
    13561 gcgagcgccg ccgcgccaac ctggccgaca tggcgatcgg cctcgacagc tcggtctcgg
    13621 cgctcgagcc catgctcgcc acgctcgaac gcaagggccg tgtgcggcgc gtccccgcag
    13681 ccgcgggctg cggcacgagc tgctgcaagt gcgacccggc gagcaccgtc gtcttcgagt
    13741 gggccggcga cgcgccggcc tcctgaggcc ggaggccttc ggctcgtgcc cggcacccgc
    13801 acgctgctgg tgatcggcat ccatcgcgag gagctcgcct tcggtcgcga tgtggtgcaa
    13861 gggctggagg tcgaggatct cgacgtgctg gagattccag aggggctatc ggggcgccgg
    13921 cccctgcctg atgagacctt ccgctacggc gcgctgcacc gggcgctcta cctgcagctg
    13981 ctgccctatg tcggagggac gcaccgcctg ctgatcgacc tgcattcggg cctcgaccag
    14041 cagggaccga gcgccgacct gctgtgtgcg gatacggcgt tgcgtgcgcg cctgcgtcgc
    14101 gcactggatg cggaaggctg taaggagcgg cctgacgcct cggtgcggat cgtgccgctg
    14161 ggtcaggcgg gcgtggtgca ggcgcgtacg gtgatccccg aggcgatctg gaacaacccc
    14221 gcgttcgcct atctgggaat ggagctttat cttccggtca cggtcgaggg gcgcgcaagc
    14281 ggggcgattc tcgcccgacg gctggtccgc cttgtgacgg ggtgcatgca ggagcggggc
    14341 gacgagccgt agggctatcg tccacgcgcg tgaatcagcg cagcaaggcc ttgcgatgca
    14401 gcccgaggtg caccccgaga caggcgacga agacgccgcc ggtgactgca tgccagcgct
    14461 tgttgccggt cgccgccagc gccagcgatg cgcccaggct gccgagcatg ccgatcttgg
    14521 cggcgcggtt gacacggttg tggatcgagc gccttgcctt tcgcggggcg gcgagtgccg
    14581 catccaaggc ctgttcgatc cgttgctcaa gcttggcggg gcttacctcg ccgtggtcaa
    14641 aaaaaaccac gatacttccc gcgacaagat tagggcgcag ttctcgaaca ccctcgagtg
    14701 gcgcaagttc cttatgtacg cgggagaggc agtcccgtcc gcgcagcgca ggatccttta
    14761 cgcggatgcg acccggggaa gatgaggcga ttctggtcat gggcaggttc ctcaacgggt
    14821 tgcttcggtt gcggtcgaat cgaggccgaa gagtggagag tttgacacca atccctggtc
    14881 gacctgccga tggttgcttc ccgcagagcc cccaggggag tccgagggtg aaagatcatg
    14941 ctttgaccac cgtccagtgg ttgtctggtg cgatctccac cggccagcgc agcaataccg
    15001 ggtcacgttg cgggtgccag aagccgaggc cacgcggcga gccgatcagg ctggcatgag
    15061 tgccgtcgag tgcgacctcg gcgagtgcgc ctgccttgtt gagttcggcg atgacctcca
    15121 ggcgctcggg cgccgccgga tgccagcgcg tcacccggtt actgcgttcg gcggataggt
    15181 agaaacctcc gtccatgccg atggcgatgt cgccgcagta acctgcgccg acggtctcgc
    15241 gactggggat ctgcagcgtc tctccgttcc acaccgccag gatgggcgct gcggcgcgct
    15301 cggccgcgtc gtcgtgctcg gcctgcagcg ccacgccgac cagcgtgcgc ccgcccgcga
    15361 ccggcaccgc gccgagcgca agatggcgca cactcaggcg cttgtccttc agccaccact
    15421 ggccgaggcg ttcgccactc tgcggatcga gtcgcaccag cgaggagtcc atgcggtcga
    15481 ggtcgcgctt gcggtcaccg gctgcgcgca ggatgccgcc gttggccacc accagcttgc
    15541 cctcggcgtc gaacagcagc tcgtgcggct cgatgccgcg ggtggggaac tccgcttcct
    15601 tgcgcagact gtcgcgccgg cgcacggcga tccagccttg ggtggagccg gtctcggatt
    15661 cggtggtgta cagccactcg cccgcggggt cgaagaccgc gtgaccgttg agagtgcgcc
    15721 cgctcttctc gtcctcgagc acctggcggg cgaggacttc gccgtcggcg gcgcagcgca
    15781 tcagccaggg gccggggcgg ttggcgcaaa ccaggaagcc gccatcgcgg tcgggcagca
    15841 ggccgtggac gcgatccggg acggcgatgg cggtctcgat gcgggcgacg ccttgctgcc
    15901 agtcgggcac caggataccg acgtagtcgg tggtgccttc ggcctttgcg ccgcgcgcgg
    15961 cgccgtcgcg gccgaggtca tgaaggctgc gccacgcggc gatcaggcgg atttcgggaa
    16021 actcaccggg tgtggtcgcg gcgagcaggt ggcgtggcag cagggcgagc gagaggccgc
    16081 cgcccagcgt gcgcaggaag tcgcgtttgt tcatcggggt gttccagtgg aaacgacgga
    16141 ccccgctggg gcccgtcgat cgatgcgctc ggatcagaac ttgtattcgc cggtcaggat
    16201 gatcgcgcgg ccggtgccgg ggatggcgaa gccgccctgg tcatacacgg cgtcgtagta
    16261 cacacggtcg aagatgttct tgacgttcag gcgcgcggcc cagctcttct gctcatacgc
    16321 gagcatcgca tcccagcgcg cgtagccggg cgcggcgttg ggcgtgaact tgccgtcgat
    16381 gaagttgctg ttcgcgttgg cggccgtggg cacgtaggcg tagcgatcgc tcttggcttc
    16441 gacgccgccg ccgatcttcc agccgccgcc gagcgcatag gttgaccaca ggttgaaggt
    16501 cagcttgggc gtgttgcgcg ggcgctgacc ctcgaggcgc gggtccgcgc cgggtgcggc
    16561 ctcgaggatc tccgcgtcca tcaccgagaa gccgctgaac acctcccagt tcggcgtcac
    16621 gcggccggcg acctccagtt ccaggccgtc ggtgcggcgc ttcctggtca ggatcgcggc
    16681 gctcgactcg aggtcggtat tgcgctccca ctccttgtcg gcacggtaca gtgctgcacg
    16741 cagggcgaga tcgccttcca tcagcatcca cttggcgccg agctcggtga ccttgctacg
    16801 ctcggccggg aagcttccgc cggagagctg gtagaggtcg gcggtcgggc tgaacgagtc
    16861 gctgtagctg atgtagtagt gggtgtactc ggtcggatgc caggacaggc cggtgcgcag
    16921 gctggtctcg ctgaagtcga gctgcggcga gttcaggctg gagtattcgg cgtcgagcga
    16981 gtcgtggcgt gcccccaggg tcagcttcca gtccgggatg aactcgatgg tgtcctgggc
    17041 gtagaaggcc agggtgtcgc cctcgtaggt gatcgccggc gcggaggtga aggcgcccgg
    17101 acgatagaag cgacccgcgc ccgggtccag gtcctgcagg ctgcggcggc tggagtcttc
    17161 cttcaggtac tcgacgccgg cgagcagctc gtgcttcatg ccgaacaggt cggcacgtgc
    17221 ggtgaggtcg gattgcaggg tcaggttctc ggtttcggtc tggcgcacct tggggctacc
    17281 ggtgctgccg tcgaagctcg gtgctgcggt ccggttgggc gcctgcgccc agtacacgcg
    17341 ctcgtagctc gcgtggcgca actgggtgcg gatttcggcc tgcgaggaca gcttatgctg
    17401 gtgcaccagc gaggtcatcg aggtgtcgct gtcgtcgaag gtgttgttgg tgccccagaa
    17461 ggtgtcggcg gagaagtcct tcgtcgggcg cttggtggct ggatcgaagg agatgccgta
    17521 atcggggttg tcgcgcgtct tcaggtagta atgattgaag gtgaattcgt tgtccgtaaa
    17581 caggccggtg accaggctga ggccgacgcc ctcgcgatgg atttcgggtt cggccccgtc
    17641 cgcggggttg ctgcgccagc tgccctcgtc gcgcttcatc acgttcagtc gcaccgcggt
    17701 gctgtcgccc agttccttgt tgaagtcgcc ggtcacttcg cggtaatcgt cgatgccgac
    17761 gctgccggtg atcctgccgc ggttgccgag cagcggcgtc ttggtgacct ggttgattac
    17821 gccgccagcc tggccgcgtc cgaacagcat ggcggccgag ccacgcagta cgtcgatctg
    17881 ctcgaggttg aaggtctcgc ggttgtactg tgcggtgtcg cggatgccgt cgagatacat
    17941 gtctccgaag gtgtagaagc cgcgcaggtt catgttgtcg cccgagcggc cgccttccgc
    18001 agcgttgaac gataggccgg agacgttgcg cagtgcttcc ttcagactgc cgacctgctg
    18061 ctcctccatc aacgtgttgg tgactgtggt gaccgcctgc gggatatcgt gcgggtcctg
    18121 caggaccttg ccgacgcgcg tcgcagtggc acggtggccg tcctgcggag cagcgtcttc
    18181 ggcagcgttg acggtgaccg tcggcagtgt cttggccgag gagggagtgg cttgtgcctg
    18241 cgcgcctgcc gacaggacgg cgagcatgat cgcgctcagg ggcagcaggg ggcgagtggg
    18301 ggcgtgcgcg ggccgcgccg cgccggaacg aacggcagct ttcatcgtga ctctctaggg
    18361 tgttggatcg ggaagtcggt gctggctggc ttcccgatcg acggagtgac gatgaccgtt
    18421 tcaggtggct ggctgggcga gacgttgcga attatggtaa aaacgcgaat cgttcgcaac
    18481 aagttttaac gagtccagaa gatttccggc ctgcggtcgc gacgttttcg ctactacgag
    18541 cgcctcgcgg tggcgctggc ggctgcggct cagtcggccg gccgccccgc accccacccg
    18601 cccccgagcg ccttgtacag attcaccgca tcgccgagcc gtgcgaggcg caactgcgcg
    18661 agctggtcct gcgccgagaa cagggtgcgc tgggcgtcga gcacggtgag caggccgtcg
    18721 gcgccttcgc ggtagcgcag ctccgccagg cgcaggctgc gcctggcttc ggcgaggatc
    18781 tcgcgctggg cggcctcctg gttggcgtcg cggaggccgt cggcgagggc gtcctcgacc
    18841 tctttgaggg cgacgaggat ggcgcggcgg tgggcctcca gcaactcgcg ctggcgcgag
    18901 cgctgcacct cgacctcggc gcgcaggcgg ccgccgtcga agatcttctg caccacgctg
    18961 gccgacagcg acagcgtgcg cgtggtgtcg gcgagcgaga gcagggcggc gctgccgacg
    19021 cccgcgcccg ccgcgaggtc gatgccgggc agcagcgcgg cgcgcgccgc ggcgacgttg
    19081 gccgccgccg cggcgaggcg ggcctcgctg gcagcgaggt cggggcggcg cagcagcagt
    19141 tcggagggca gaccggcgtc gatgcccggg acctgcaagg cctcgaggcg ctcgtcgccc
    19201 gcgatgccgt cctgcggatt gcgcccgagc aggatggcga gcgcgctgcg ggtctggcgc
    19261 agctgtacct ccaggggctc gatggccttg cgctggttga gcacggtgct gcgctgctgg
    19321 ctgagctcga gcgccgaggc ggcgccgttg tcgtagcgtg cctgcaccac gcgcagcacg
    19381 ccctcggcga tggcgaggtt ttggcgggcg atctccacgc gctcctgcag cgcgaggctc
    19441 tggaaccagg tcgtggcgac gctcgcgctc agcgacaggc gggcggcgtc gtagtcgtgg
    19501 cgggtggcgg cgaggctggc gcggctggcg tccacgccgg cggcgatgcg gccccacagg
    19561 tcgagctcgt agctcgcgcc caggctcagg tcggtgctgc cggactcgtt gccgcccacg
    19621 ttgcgcgtgg cgctgccgcc gcccaggttc agcgccggca acagcgacgc ccccgcctgg
    19681 cgcagcgcga gctctgcctg caccacgcgc tcggcctgga tgcgcaggtc cggcgcggcg
    19741 gccatcgctt cggcgaccag ggcgtcgagc cgggccgagc cgaagccttg ccaccaggct
    19801 gcgtcgaccg ccgcgccctc cgcgggggcg gtctccgccc atgcgtccgg caggggctgg
    19861 tcgggtcggg cgacgggttc ggtgatcgcg cagccggccg cgagcagggc ggtcagcaag
    19921 ggcagcagcc ggctgcgcag gcggctgcgc agcaacgagc ttgccgagat gcgggcttgc
    19981 ccgcgactac gggggcgtga ggagcgtccc ccacgggcgg agccgaccgt ctccccgcag
    20041 tcgcggccgt tcgtgatcga ttgggtatgc atgtacaagc ctattccgaa gccagcgcaa
    20101 ccaccgggtc gagccgggcg gccttgcgcg cgggcaggta gccgaacacc aggccggtga
    20161 ggaaggcgca gctgaaggcg agcaccaccg gcgtgagcga gtactgcacc gcggtgccga
    20221 aggcctcgat gatggcggcg gcgccgagcc cgacggcgac gccgatcagc ccgcccaccg
    20281 ccgacaccac cagggcctcg atgaggaact gctgcaggat gttgcgcgtg cgcgcgccgg
    20341 tggccatgcg gatgccgatc tcgcgggtgc gctcggtgac cgacaccagc atgatgttca
    20401 tgaccccgat gccgcccacc agcagcgaga tcgccgccac cgtgccgagc agcacggtga
    20461 gcgtgttctg tgtttccgac acggtgtcga tcaccgaggc catgttgcgg atctggaagt
    20521 cctccacgcc gtggcgtgca agcagcaggc tctgcactgc ggcctgggtg tcgtcgatct
    20581 ggccgacgtc ctcgaccgcc accgtcacgt tgcgcaggaa gcgctgcccg gtgatgcgca
    20641 ggctggcggt ggtgaagggc atgaatacga tgtcgtcctg gtcctgcccc caaggggtgg
    20701 cgcccttggg ggtcatcacg cccatgacct ggaaggggat gttgttcacc aggatgaact
    20761 cgcccaccgc gtcgcgcccc gggaacagcg cgcgcgccac ggtctggccg agcacggcga
    20821 cggtggcgta gcgcgcctcg tcctcggcgc tgaagaaggt gccgctcgcc ggcgcccagt
    20881 tgcgcgcgac gacgtagtcg gccgaggtgc cgttgacgct gctgcggtgg tcgaggttgc
    20941 cggcgcgcag cgtgatcgtt gcgccctgct cgggcaccga ggcgagcacg ttgggcagct
    21001 cggcgatggc ctgcacgtcc tcgatcacca gcgtggcggg ggcgtcgcgc ccgcgtgtgt
    21061 tgggcgcgcc cggacgcacg gtgagcaggt tggtgcccat cgcgctgacc tggtcgatca
    21121 ccttctgctt ggcgccgtcg ccgatcgcca gcatggcgat caccgaggcc acgccgatga
    21181 cgatgccgag cagggtgagg atggtgcgga agaggttggc gcgcagcgcg cgcagcgcgg
    21241 tgcgggtggc ctccaccacg tcggacagcg gcgaggtgcg atcgacgtga ggggcgaagt
    21301 ccggctccgg cacctgcggc gggcgcggcc cggggtcggc gacgatgcgg ccgtcgcgga
    21361 tctcgatgat gcgctgcgcc tgctcggcga cctcgcgctc gtgcgtgatc agcacgatgg
    21421 tgtggccggc ggaggagagc tcggcgagca gcttcatgac ctcggcgccg ctccggctgt
    21481 cgagcgcgcc ggtgggctcg tcggcgaaga tgatgcgacc gccgttcatc agcgcgcgcg
    21541 cgatcgacac gcgctgttgc tggccgccgg agagctggcc ggggcggtgg tggatgcgct
    21601 cgcccaggcc caggcgggcg agcagctctt cggcgcgggc gtggcgctcc tcgcgcggca
    21661 tgccggagta caccgccggc acctcgacgt tgtcgcgcgc ggtggcgccg ccgagcaggt
    21721 tgtagctctg gaacacgaag ccgaaggcct cgcggcgcag gcgcgcgagc gcgtcgcggt
    21781 cgagcgcggc gacgtcctcg cccatgaagc ggtaggtgcc gccgctgggg cgatcgaggc
    21841 agccgaggat gttcatcagc gtcgacttgc ccgagcccga ggcccccatg atggcgacga
    21901 actcgccggc gtggatggtc aggtcgatgc cgtgcagcac gcgggtctcg acctcgccat
    21961 tgacgaagct gcgcgtgatg ccgcggagct cgatgagcgg ggctgcagtc gacgacgcca
    22021 cgcggggggc cgcccgcgtc gccgtggcgg ccgccggcgg atcggaggag gggcgcgcgc
    22081 cctcgcctgg aaggcgttcg accttcatag ccgcggggtc atctgcgggc ggccggtgcc
    22141 gttgccgacc accaggccgg agaccacgcg ctcgccctcg gccagcccgg acagcacctg
    22201 cgcctgcaca cggttggaga cgccgagctc gaccttgcgc tcttccagcg cgccgcgtgc
    22261 gtccgccacc cgcaccgtcc ccgagcgcgg cgccgcgccg gtcgcgcccg gtgtgaggcc
    22321 acgcccctgg cccgcgccca tgccgcctcc ccggcccggg ccgccattgc cggcgggctg
    22381 cgccgtgccc ggcgggggcg cggcggcggg ggcggccgcg ccgcccgcct ggggcgcgcg
    22441 cgcctggccc tgcgcgagcg cggccatcgg gatcagcagc gcgtccttcg cctgcgcgac
    22501 cacgaagaag acctgcgcgg tcatctgcgt catcagccgg ccgtcggggt tgggcacgtc
    22561 gaagagcgcg ttgtagagca ccacgttgtt ggtcaccgtg ggcgtgggct cgaccttctc
    22621 gagcttgccg tgccagcgct tgccgctgcc gcccagggtg gtgaagtagg cctccatgcc
    22681 cagcttgacg cggccgatgt cggcctccga cacctgtgtc tgcacggtca tcgtggacag
    22741 gtcggcgatg cgcatcacca ccggtgcctg ctggttggtg ttgagcgtct ggccctggcg
    22801 cgcgctgatc gacaccacgg tgccggccat cggcgacagg atgcgggcgt actgcaggtt
    22861 ggcctcgtcg gcgcgcaggg tggattcgat ctgctcgatc tgcgcgcgca gcgcgtcgag
    22921 ctgggctgcc gccgacttgg ccgaggcctc ggcggtctgc aggctctcct tggtggtggc
    22981 gtcctcggcc atcagcgcgc gctggcggcg gagctggatc tgcgcgaggg cgagctgggc
    23041 ctcgcggtcc tggagctgcg cacgcaggtt cctgagctgg gcgcgcgagg cgtcgacgcg
    23101 cgcgcgatac accgtggggt cgatctcggc gagcaactgg ccggcctcca ccgtgtcgcc
    23161 gacctcgacg tggatcttgc gcagctggcc ggagacctgc gcgcccacgt ccacgtagtc
    23221 gcgcggctgc agggtgccgg tggcggtgac gacgtcctcg atgtcgccac gctgtacggc
    23281 ggagaactgg tagttggtgg cggcgtcgcg ctcgccgagg aaggcgctgc ggccgtacca
    23341 gccgccggcg agcagcagcg gcaccaggat cagcacggcg cggcgtcccc agcgcgggcg
    23401 ggcggttcgg gtggagggct tgtcgtcgtt catggagttc cgcgttctcg gccgatgggc
    23461 cgggtcgttc gtcgagtcat gggtgagagg atagcgggtg ggcggaaggc tgcttgtatc
    23521 ggaatgcagc gccgccgcga acagcgggaa gacctcgacg aaggtgctgc gttccgtcct
    23581 aaggtgccca aaggttgatc atgatcaaga aagcattgct ttagacgaga tctaataagt
    23641 gcatcgaaac actccgtccc aagcggggtg cgtatcctgg aagtggcaat tcgccgagct
    23701 ggcaaggaga agcatcatga tgatgaagtt gaaggcaacg agcgtggcag tggctttggt
    23761 ggtggcgggc agtgcgtggg ccgcgtcgac cgtccgggat gaattgatca agccgatcga
    23821 acccgcgaag gtggacaacg ccgccaaggt agagctcggc aagaagctgt ggttcgagcc
    23881 gcgcctgtcg atgtcgggca tcatctcctg caacacctgc cacaacctgt cgatgggcgg
    23941 caccgacaac ctgaagacct cgatcggcca cggctggaag gccggcccgg tcaactcgcc
    24001 cacggtctac aactccagcc tggcgatcgc ccagttctgg gacggccgcg cggccgacct
    24061 caaggagcag gccggcggcc cgatccaggc cgacgtcgag atgaacatgc cgcacaccct
    24121 ggcgatcggc atcctgcaat cgatcccggg ctacgtcgcc gagttcaagt cggtgtatgg
    24181 caaggacaag atcgacatcg acatgatcac cgactcgatc gccgagttcg agaagaccct
    24241 ggtcacgccc gactcgcgct tcgacaagtg gctcaagggt gatgacaagg cgctgtccga
    24301 gaaggagctc gcaggctaca ccctgttcaa ggagagcggc tgcgtggcct gccacaacgg
    24361 cccggcggcc ggcggcacct ccttccagcg catgggcgtg gtcgagccct acaaaagcag
    24421 ttcgcccgcc gaaggccgct ccgcggtcac tggcgccgat gccgaccgct tcaacttcaa
    24481 ggtgccgacc ttgcgcaacg tcgagctgac ctatccgtac ttccacgacg gcgaggcggc
    24541 gacgctcgag caggcggtgg atacgatggg tcgcctgcag cttggtcgca cctacagcaa
    24601 ggacgagatc ggccagatcg tcgccttcct gaagacgctg accggcgagc tgccgcagat
    24661 cgcgatgccg atcctgccgc cgtcgagcaa cgagacaccg cgtccggatc cgttcaagta
    24721 atccggcgag tcatcgagct tgccgcagga atgccggggc acggacgcga gttcgtgccc
    24781 cggtactagt tctcatggat tattgacacg atccgggacc cggtccagca ttcagacagg
    24841 gtccaatgca tatccgcagt ggttgcggag tcgctaccag aaggtcgatc gccatgatga
    24901 acacctgcac ctacgcctcc tccgacgcca tcgcctgcct gcgccaggcc ggcattccgg
    24961 tcacgcacca gcgcatcgag atcgcgcggg cgctgttctc ggcgccggtt catctctccg
    25021 ctgaccagat ctgggccaag gtgctcgatg cctcgcccga cgtctcgcgt gcgacggtgt
    25081 acaacaccct gcggctgttc agcgagaaga agatgatccg cgagctgttc gtggaccccc
    25141 agcgcgtcgt gtacgactcc acgaccacgc cgcatcacca cctctacaac atcgacaccg
    25201 gcgaggtgcg cgacatctcc gacgacgagc tgcgcgtgat cggcgagccc cgcctgcccg
    25261 ctggcgtcgt gctcgacgag atcgacgtca tcgtccgcgt gcgtaaccgc gtggcctgat
    25321 cgtcgcgtcc cgggagccgg gacggagagg tggtcgatga aaaaggcgcc atggcgcgga
    25381 ttcgttccgc gtcctggcgc ctttcttcgt tgcggcctcg atgctcagcg ttccggaacc
    25441 gtcacgaagc ccatcttctc gatgccggcg ctgcgcgcct gggccatcac gtccgcgatc
    25501 acctcgtagc gcgtgttgcg gtcggcgcgc aggtgcagct cgggctgggg tttctgcgcc
    25561 gcggcggcgg cgagccgcgc gggcagggcc acctcgtcga ccgcctcgtt gttccagaac
    25621 acccggccat cgccgtcgat cgacagcgcg accgtctcgg gcttctgctc ggtgggcgcg
    25681 ctggaggcct gcggcaggtc gatcttgacc gagtgggtca gcagcggcgc ggtgatcatg
    25741 aacacgatca gcagcaccag catgacgtcg atcagcggca ccatgttgat gtcgctctgc
    25801 ggggcgcgtg tctcaccctg gctgaatcca ccgaaggcca tcacgccgct ccgtgcgcgg
    25861 cggccggcgt gcccgcggcg acttcggccg cgcgcggggc ggcgccggct accgcggcga
    25921 tgcgtgagcc ggtggcgaac caggcatgca ggtcgtgcgc gaaggcgtcg agctcggaga
    25981 gctcgacgcg gttggcgcgc gtgatggcgt tgtatgccag caccgccggg atggcgacga
    26041 agaggccgaa ggcggtcatg atcagggcct cgccgaccgg gcccgccacc ttgtccagcg
    26101 tcgccatgcc cgagacgctg atgttcacca gcgcgtgata gatgccccac accgtgccga
    26161 agaggccgac gaagggcgcg gtcgagccga tcgaggcgag catggtgagg ccggactcga
    26221 gcgccgcggt cgacagcgcg atcgacttgc gcagggcgcg ggtgatgacc tcgtcgccat
    26281 cgagcgtgcc gccgagcgtg ttgccgtggg tgtgacggcg caggtgctgg gcggcggctg
    26341 cgccctgctg ggcgagcgcc tcgacgggcg actcgggggc gcgttcggcg agcacgcgca
    26401 gtccggcgtc gaggtcgggg gcggcccaga aggcctcgac cgcgccgttg tggccgcgcg
    26461 cgcgcaactg gcgcagggcg cggctgagga tcaggtacca gctggtgatc gacatcacca
    26521 gcaggatgag cgcgaccgcg cggatgatgt tgtcggattg cgcccacagg tgggcgaggc
    26581 cgaaggcctg cgaactgtcc atgctcagtt tccttggagt ttgaagacga tgggcaccag
    26641 gacccaggat tcgatcgcgg tgtcgccgcg gcgtgcgggc acgaagcgcc agcgcgccac
    26701 cgcctcgcgc gcggcgcggt cgagacggtc ggagccggag ctggtgcgca gctcgacctg
    26761 cgcgggctgg ccgtcgggcg aaaccagcac gcgcagcgtc acctggccct cttcgcgcag
    26821 gcggcgcgac aaggccggat agccggggcg cgggttgttg aggtaggcgg cgtcgaagcg
    26881 cgcggcggtg accgttgcgg gcgcggccgt cgccgcggct gcggcggcag gcggtgcggg
    26941 cgcgggcggt ggcggcggcg cggcgtcctc ggccgcgctc agcgcggtgg gtgactcggt
    27001 gaccggcgcg ggcttcttca ccaccggctt gggcgtcggc ttcttcacca ccggcttggg
    27061 cggcggtggc ggcgcgggct cgggcggacg caccaccggg ggcggctcgg gttcgggcgg
    27121 gcgcggcggc tcgacgacgg gctcaggcgg cggcgcgggc gcgggttcga cggccgcggg
    27181 cgcctcgatc aacgcgacct ggatcggtat cagctcggcg ggcagcgggc gctcgtcggc
    27241 gaggcgggcg agcagcgcgg cgccgccgag gtgggcggcg acgaccaggc cgaggaggat
    27301 gctgcgccgc agcggcgagc ttcccagacc gcgtgccgcg tggatcggga gaaaggtgcc
    27361 atccgatccg tgcgcgcgtg gatcgatggc cgccgcttcg tggtcgagat caggctcgac
    27421 cgacagcgat ggggaggagg ggggcagcag cgacaatgcc tgggcagctt ggtgcatcgg
    27481 agcggaggcg gcgagccgcc tccgcggagg cagcgttggg ttggtcgggg tcgagcgggc
    27541 tcaggaagcg ctcggttcca tctgcgactg caggtagttc tgcaggccga cgctgtcgac
    27601 caggccgagc tgggtttcca ggtagtcgat gtgttcctcg gtgtcttcca ggatgtgctc
    27661 gaagagctcg cgcgacacgt agtccttgca ggattcacag tacgcgatgg cctcgaccag
    27721 gttctcgcgc ccgccgagct cgagcttgag gtcgccctgc atgcattcgg gtacgttctc
    27781 gccgatcagc agcttgttga ggttctgcag gttgggcagg ccctcgagga agagcacgcg
    27841 ctcgatcagc atgtcggcgt gcttcatctc ctcgatcgac tcgtcgtatt catgcttgcc
    27901 gagccgctcg aaaccccagt tcttgtacat gcgcgcatgc aggaagtact ggttgatcgc
    27961 ggtgagttcg atggtgagct gcttgttgag gtactggatg actttcttgt cgcctttcat
    28021 gttgactcca gggatacggt gaatgctggc gagatgcccg cgagcaagcc tgtcatcccc
    28081 gtacgtggcg ccgggatgac ggccgagcgc aggcagtcgt gcgcgcagcg cgcgcaacga
    28141 ccgcactcgg ccgtgacgcc gagcgactgg cgcaggtcgc gcaaggtccg cgcgccctgc
    28201 gcggcggcgt gatggatctg gcgctcggtg accgcgttgc atacgcacac gtacatagtc
    28261 tagcctcccc gcggggtttt gccccgatat ggcagcatct ggaagatcac ttggtgagga
    28321 tcagcttgcc gttgcgcgtc gcgcgcagca cgtactcgct gccctcgtgt tcgatccgca
    28381 cctcgcgacg ctcgccgagg agttccttgc tggtgagcag gaatcgcggc ggagccaccg
    28441 aagactcttc gacgagcctg tccggcgcgg aagcggaagc ggaagcggtg acaggaacgt
    28501 ccggtgggtg catgatcgaa tggcgttaaa aatacgaatg attcgcatta gaacacgagc
    28561 gcggagtgca tgcaacgctt gcgtgctcgg aatgtctccg cgcgttactc gaggcgcagc
    28621 agcacgttca ggggctggcc gacgacagat gcagccggca ggtaggcgag tgcgctcggg
    28681 tcggtgagta cgcggcggag cgcgtcttcc tggtcgtttg cctcgtgcgg cgggtgggca
    28741 cgcccggtga acaccatgcg cgaccagtag gcgcggatct ggctggggtt cttggcggtg
    28801 aggcgctcgt agaaaaggtc gcgctcgggg ccggcgggca ggtcgagcag gcgggcgctg
    28861 cgcccgtccg gcagggaggt gcgtcggccg aggtagagct gggcggccgt ctcgcggtcg
    28921 agttcgggga tgccgccggc gcgtgcgctg accagcacga cgccctgtgc gcgtgccgcc
    28981 tgcccgaacg agagcgcgac caggaggatg agcacgcggc cgatgcgtcg gcggcgatgt
    29041 ggcggatcag aacaccacat cgaccgacac gctcagcaga ttgatgttgc gatcgtccag
    29101 cccgggtgca aaggggtcgc cacgagcgat gaaggtgccg tgcgcgtcgc ggctggtgtc
    29161 gatgtggctg aattccgcct tgagcgcggc gtgcggcgtc aggtcccagc gcgtgcccac
    29221 ggtgatgctg cgctgcgcct ggttgcgcga gcgattgaac gctgccagcg cgttggcgct
    29281 catgtccgaa ttcgccagcg ccgggtcggc gatcggctcg tcctggcgct gccgggccag
    29341 gccgacatag ggcatcagcg caccgaagcg ccgtccgacc gatacgtagg ctccggtcgc
    29401 actattggtg aacgcgctcg ccttcatgcg cgcgagctcg gcgatcaccc gccagcgccc
    29461 gtcgtcccat tgcatgccga gcgagctgaa gcttgcatga gcccccttgc cgctaaggcg
    29521 cgcctgcagc gccggcggga tattccatga ctcgacgaga tcctggtacg actgcgaggt
    29581 ccggatcacc gacagttccg cttcggcgtg gcttgcactg aagctgaact cgtcgcgctc
    29641 gagggttgcc gtgagcccgc gcagccgcct gagatggccg cgaccgccgc cgatcaccgg
    29701 aatgcggctg gtgccgaaat acgggtgcag ttcgatgaag gaatcgccga ggcggctgcg
    29761 gtaaagcaga tcgacgccgt ccatgtcggt gaaggggttc aggccgtaga cctcgaccgg
    29821 agggcgcacc cagggctggc tgtagttgat gtctgcggtg tcggacagca tgaagaaggg
    29881 gctgcgcagg cggccggccc gcacggtcag cgctgggttg aggctgtggc tcaggaaggc
    29941 gagggcgggg cggggggtgt agtcgccacg ctgggtctcg cgtgtcacca gttgcagcac
    30001 cgcgccactg ccgttacccg cttgccagcc gaactgcagc ccgagcaccg agtccggacc
    30061 ggtgtcgacc cgattgcctc ccggtgcgtc gatgcccacg cgggcgaact ccagctcatc
    30121 cgagcgggtg taggcggctc cgagggtggc gaagcccgag acctgcaggt cggaggcggt
    30181 tgccggatcg atgccgcctg caagtgcagc gatcgaggcc agcagcgtga ccgcgcggtg
    30241 cagggtatgg cgaagggggt ggcgagtact
//
LOCUS       DAOTIN010000032        30233 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_1706_length_30233_cov_8.654980, whole genome shotgun sequence.
ACCESSION   DAOTIN010000032 DAOTIN010000000
VERSION     DAOTIN010000032.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 30233)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 30233)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30233
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1706_length_30233_cov_8.654980"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(49..456)
                     /locus_tag="P5537_06965"
     CDS             complement(49..456)
                     /locus_tag="P5537_06965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HRV77819.1"
                     /translation="MSETLQAGLSLTRKYDIDAARTIAFMGDECRVYSTPALLYDIEV
                     CCRDLLLEHIGEGKDSVGTRVELDHVGATLLGMWIEITVKLVEVNGPAVVFEFSARDA
                     LEEVARGRHNRFVVGVDKTRQRLLGKLAKAQAA"
     gene            complement(521..>2146)
                     /locus_tag="P5537_06970"
     CDS             complement(521..>2146)
                     /locus_tag="P5537_06970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HRV77820.1"
                     /translation="AQVALHELVLDCACDGEAVQIVAARCSVGAPPLLRVARPIHKID
                     RLLHPERIGIVGASASGMNFGRIILRNLLGSGCPPERLCVIRPGGGEIDGVACIENLA
                     AIEGKLDLLIVAVAADAVYPLVDEIIAAATVEAVMLIPGGLGETAKSREPAAALAARI
                     NAAHARGDGGPIFLGANCLGVVSHPGRYDSWFIPLERLPKPQKVPERRAVMLSQSGAF
                     MITRLSHNPWLDPRYMIAMGNQTDLTHGDLLSWFAAREDVDSIGIYVEGFRDLDGLAF
                     ARAVRRAVLAGKQVVVYKSGRSEAGQAGVMGHTASIAGDPVLFAAVLAQAGAIVTDDV
                     EVFDDLFYMAGTLHAKRIGGDRLAAASGAGFEAVSAADASVGATFSMRMATLSADTFA
                     RIEAVLAEKKLAALVEVRNPLDMNPGADDDAHVRITAAMADDPGVDAVVVGLDPTAPM
                     VRALEQSRLRPGYDLSDPESTVHTLPPLVARTDKPIVAVVDAGRLYDAMAAGLMDRGV
                     CVFRNVARGTRALVRYVEARMDAERIRRHFGRS"
     assembly_gap    2147..2246
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<2247..2766)
                     /locus_tag="P5537_06975"
     CDS             complement(<2247..2766)
                     /locus_tag="P5537_06975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HRV77821.1"
                     /translation="MTEVRSHAASPAAGEAARIYHTARAAGRATLDAGELARLLAAAE
                     LHTASAPAGAIELSIRVHATREFGLVLGAGAGGLDAALDPANFARERAAVHAAVELTD
                     GADFLARFRRTIAWQRIAALAARRGVQAPEAELARLFEAALQLAAGGLPDTPGAQVAL
                     HELVLDCACDGEA"
     gene            complement(2856..4175)
                     /gene="paaF"
                     /locus_tag="P5537_06980"
     CDS             complement(2856..4175)
                     /gene="paaF"
                     /locus_tag="P5537_06980"
                     /EC_number="6.2.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047475 - phenylacetate-CoA ligase
                     activity [Evidence IEA];
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate--CoA ligase"
                     /protein_id="HRV77822.1"
                     /translation="MSNEKPATPERMSRAELQALQLERMRWSLQHAYDNVPHYRHAFE
                     AAGVRPSDLESLADLAKFPFTAKQDLRDNYPYGLFAVPMSKVVRVHASSGTTGRPTVV
                     GYTKGDIERWAAVMARSLRVAGASCEDIILNSYGYGLFTGGLGAHYGGEALGATVIPM
                     GGGNTEKQIQLIQEFRPTVIMATPSYMLTLADTMQRMGLDPSSTTLRLGMFGAEPWTN
                     QMRAEIERMLGIDAIDVYGLSEVMGPGVACEFVGHKDGPHIWEDHFYPEIIDPVTGEV
                     LPDGERGELVFTSLTKEAMPVIRYRTRDLTRLLPGTGCTMRRIDKITGRSDDMLIIRG
                     VNVFPTQIEEVLLRHDKLCGHYQLVLTREGHLDQLTVRAELRPELADRIGQGLRRQIG
                     EEVRHAIKSFVGISAEIEVLDPDSIERTQVGKAKRVIDRRERVASEV"
     gene            complement(4165..5520)
                     /locus_tag="P5537_06985"
     CDS             complement(4165..5520)
                     /locus_tag="P5537_06985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HRV77823.1"
                     /translation="MGQAYSTIAFDPAKCDGCGKCMTACASVKFDSTDTTRSLIQIVR
                     SGGASIEPPRPGEFELALCRQCADPKCVTVCPAGALGKNGATGVIDWDASKCVDCLLC
                     TIGCSYAGIALDEHSGRVSKCDTCDGKPACVPACPTGALRHITTARIYNEVGSWEDLF
                     APGLAGCQGCNTELLMRHALRRVGPDTVLATPPGCVPGMGSVGFNGTTGTKVPVFHPL
                     LTNTAAMLAGVKRQYERVGRKVTTMAIAGDGGASDVGFQSLSGAAERGERILFMVVDN
                     EGYMNTGMQRSSCTPYGAWTSTTPVGEHTRGKSQDAKNLPMIMINHRCEYVATASTAY
                     MEDLYDKLDKALAASERGFAYLHVYSPCTTGWRFQSALNIEVARKAVESNFVTLWEYT
                     PESGLHFTRPVNDPLPVADYLKAMGRFRHLSPEQVEHIQNKVAENLRFVRKIAEQADE
                     Q"
     gene            complement(5531..6787)
                     /locus_tag="P5537_06990"
     CDS             complement(5531..6787)
                     /locus_tag="P5537_06990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HRV77824.1"
                     /translation="MHTTDYLIAGSSHAALEAINAIRMHDGEGAITVVTRDPHRPYSP
                     TVLPYVVSGRSTPERVYLRDDDFFAHNKVDYRSGCALAGIDPAAHQARLADGSTIAYR
                     KLLLATGASPVVPPIPGIDRVDYHVLRTLDDATRLRAAMAGSKNAVVLGAGLVGMHAA
                     ENLVKAGASVTIVEMSKQLTSGYFDEVAAGMIEQAFLGNGAKIRTGHRVVGLEPGPDG
                     ATLQLDNGDTIPADLLLVAVGVRPELGYLDGSGIATERGILVDDSMRTSVDDVWAAGD
                     CAQARGFFTGTPVMNAILPDATVQGRIAGMAMAGDPGLKPYPGGVPLNTYHFFGRHAI
                     SVGSAAVPEGGRAQVRFDAASGRYLRAVFDRDERLTGIFGVNEFFDAGVMAQLIVRRT
                     DLGPLRERFFAQPLATGRELMSQLWR"
     gene            complement(6812..8068)
                     /locus_tag="P5537_06995"
     CDS             complement(6812..8068)
                     /locus_tag="P5537_06995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011238866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylglyoxylate dehydrogenase"
                     /protein_id="HRV77825.1"
                     /translation="MNTTTTEAAAHTVAERAPQLMLVEGNEAAALGVALARPDMVAVY
                     PITPQTSLVEKLAKLIADGGMDADIVDAEGEHSVLSVLQGGALAGGRTYTATCGPGLA
                     FMFEPYFRTSGMRLPMVMTIVTRDGITPQSVWGGHQDAMTVREAGWIQLYCETVQEVL
                     DTTVMAFRLAEHHDVMLPVNVCLDGNYLSYGAARVEMPDQAEVDDFMGRKDVNWHVAL
                     DPLRPMAVDPLTGGSGGTGPETFVRYRRGQCAGMKNALRVITEMHEDWARRFGDSHRF
                     APLVEEYRLDDAEYAIMTLGSMTGAAKDAVDEARAAGEKVGLIKIKTFSPFPVEALKH
                     ALRDVRALGVVDRSVNFRWNCGPMFQETLAVLYRLGRQLPAQSFIGGLAGADLTVATF
                     HRVIAETRALLERPAADEPVWLNAKD"
     gene            complement(8065..8367)
                     /locus_tag="P5537_07000"
     CDS             complement(8065..8367)
                     /locus_tag="P5537_07000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HRV77826.1"
                     /translation="MSERHTRYPAWHLKQHGVPEDLCPVATELTPMLPGDWRSFRPVV
                     DRDKCVKCAVCWLYCPVQCVEEHAAWFDFNLKTCKGCGICAHECPQRAIIMVPEAQ"
     gene            complement(8364..8936)
                     /locus_tag="P5537_07005"
     CDS             complement(8364..8936)
                     /locus_tag="P5537_07005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HRV77827.1"
                     /translation="MYEVRIHGRGGQGAVLAAQLLATALVFDGKYAVSIPAFGFERRG
                     APVVSFIRASETPIRQLTNIYAPDCIICVDPTLARTVDIFAGLKPGGAMVQATSRPLE
                     EVAVADTVGTVGLCDAVRIATEIFGRPITNTLMLGAFARTTGQVSLAALKKVIEQSDF
                     RDAGLAQNLTALERGYEETTVHTLERRLTA"
     gene            complement(9001..9882)
                     /locus_tag="P5537_07010"
     CDS             complement(9001..9882)
                     /locus_tag="P5537_07010"
                     /EC_number="1.8.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0019645 - anaerobic electron transport
                     chain [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit"
                     /protein_id="HRV77828.1"
                     /translation="MRGVEPELQPFWDERAAGNFIGGGTGTGLLLWSAIAASGHGTAI
                     GLPLFLALACIGVGLFCVWMEIGRPLRALNVFFHARTSWMTREAIVAGPLFLCGLVAL
                     LSGWLFFAWLAALIGLIFLYCQARILQAARGIPAWREPALLPLIVVTGLAEGAGMLAL
                     LSPLLAGSPGAEFALPLLVLVVLRLWLSRRYAAHLARPNNAPLKTLRALRETDRHFLL
                     LGHYLPATVLVLALVAGGSFGTALLALAGIAVAASGWLFKLALITRIAYTQGFALQQV
                     PARTPGYSHPGVKPGWN"
     gene            complement(9879..10529)
                     /locus_tag="P5537_07015"
     CDS             complement(9879..10529)
                     /locus_tag="P5537_07015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HRV77829.1"
                     /translation="MTRYAMVVDLRRCVGCQTCTAACKHTNATPPGVQWRWVLDVEAG
                     EFPDVTRSFVPVGCQHCDEPPCETVCPTTATKKRADGLVTIDYDLCIGCAYCSVACPY
                     NARYKVTRDTPAYGEGRMPNEVKRADPARIGVATKCTFCSDRIDYGHAHGLVPGVDPD
                     ATPACANACIASALTFGDIEDPDSKASRLLRENEHFRMHEELGTGPGFFYLWEKKQ"
     gene            complement(10526..13267)
                     /locus_tag="P5537_07020"
     CDS             complement(10526..13267)
                     /locus_tag="P5537_07020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HRV77830.1"
                     /translation="MTVSSPQGTTKVATYCYQCVAGPDLLKVKVEDGVATAVEPNFDA
                     EDVHPAAGRVCVKAFGLVQKTYNPNRVLQPMKRTNPKKGRHEDPHFVPISWDEALDTI
                     GAKLRGIRETGLLDASGYPRVAASFGGGGTPTAYMGTFPALLAAWGPVDMSFGSGQGV
                     KCYHSEHLYGELWHRAFIVCPDTPRSKYILSFGSNIEASGGVCGIWRHAAARVEQGVK
                     RVQFEPHLSVTGGCSAEWVPIKPKTDAACMHALIHVMLFENARSRLDIDFLKHRTASP
                     YLVAPNGFYLRDPDTRKPLVWDLKTGRAVAFDTPDIDPALDGDFIASGLEVLPDAELV
                     THEGVAVRSAFGKLLDHERGFTPEWAQGICDVPAATIRRVANEYLDHAEIGATIEIEG
                     RALPYRPVAVTLGKTVNNGWGGYDCCWARTLMACLVGALDVPGGTIGTAVRLNRPAND
                     RQSSAKPGVDGFMDYPFNPTDKENWISRPQIRNANRTLVPLVANSAWSAALGPTHLAW
                     MQQRHGFESFPEPTQPDVWFFYRTNPVISFWDTPQVAEAVAKFPFVVAFSYTRDETNH
                     FADILLPDCTDLEGLQMLRIGGTKYVEQFWDHQGFALRQPAVPPQGDTRDFTWISTEL
                     ARRSGILDIYNKAINRGAAGVPLKGPNYDFSLQPDRAYGVEEIWDASCRAASAELTEG
                     AEDHGLEWWKEHGFRTIEYPRLQWYLYPHLVDQGLRFEMPYQERIYRIGEELGRRLHE
                     SGIDWWDRQLTEYRPLPEFHDFSHLIKHAVISNLGGRDEDFPFWLLTARSMQYSWGGN
                     VSLQMVREVAANVKGHRGVIMNPTAARKLGIEDGDLVEVRSPLRETRGRVVLRQGIRP
                     DTLLMVGQFDHWITPYAKDFDVPSMNALVPMLMDLTDATGSAADIVPVSIKRIGGTQ"
     gene            13618..14271
                     /locus_tag="P5537_07025"
     CDS             13618..14271
                     /locus_tag="P5537_07025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS and ACT domain-containing protein"
                     /protein_id="HRV77831.1"
                     /translation="MFVENIMTREVLHVGPEASFSQVSEIMRLKKVRHVPVIDQDRKV
                     LGIISHRDVQRAQPSMITTLDVGEVKYLLSKIAAADIMHKSVVSCSPRTQIEEAARMM
                     RPKKLGCLTVVDDAGRLVGIVTSVDLLDFFLDITGCWVEGATRITVKLQDRAGQLAAL
                     LASVNAQGGYIVSVVSPRTPQSEGLRTATIRFEAKDAGAVVQGLREAGYELSVDQTA"
     gene            complement(14502..15041)
                     /locus_tag="P5537_07030"
     CDS             complement(14502..15041)
                     /locus_tag="P5537_07030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin family protein"
                     /protein_id="HRV77832.1"
                     /translation="MSKPDPQETGIHSVEHLLAHALAMEVEAVERYESLADQMETHNN
                     REVAALFRKLAEIEKLHVDNVNDISEGHTLPHIAPWEYSWEAPESPEAPSVSAEGLHY
                     MMHPYHAISMALEAERRGVDFYDRLVAQSEREDIRKLAAELCETEREHVTLLEAWLSR
                     FQPPPKGWNEDPDPPLLQG"
     gene            complement(15038..15877)
                     /locus_tag="P5537_07035"
     CDS             complement(15038..15877)
                     /locus_tag="P5537_07035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:ferredoxin oxidoreductase subunit
                     beta"
                     /protein_id="HRV77833.1"
                     /translation="MEATSTCPSYSARDYKSEVKPVWCPGCGDYSVLGSITKALAELS
                     IPPERVALVSGIGCSSRLPAYTNVFGFHGVHGRALPIATGIKVSRPELTVIASGGDGD
                     GFSIGGNHFMHACRRNVDMTYIVMDNEVYGMTKGQASPTTAPDWEKSKLTPQGTGINP
                     FHPLVIALAAGANFIARGFSGDQNGTAQLITEAIRHPGFSFVQLLSPCVTFRPEQRDW
                     KDMVHPAAVDPTDDPARAARRLMTDDGFNVGVLYRGSRKPFQPERQASVDSVADLEKE
                     FVL"
     gene            complement(15880..17598)
                     /locus_tag="P5537_07040"
     CDS             complement(15880..17598)
                     /locus_tag="P5537_07040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase subunit alpha"
                     /protein_id="HRV77834.1"
                     /translation="MTARSVSITFAGSGGAGVMTAGNMLLDAAGRAGWYAYMTRSSGA
                     QIRGGEAAAMMRLSTSPVQSHDDHFDVLVAIDWQNVGRFSAEIPMTSDGLVLGDPDGG
                     DFPEQIGAKGARCADIPFKKMAKEIEGGRPNMIALGAVAGLVGLPEDAVLGVVRDSLA
                     KKGEAARTASEASVRAGMAFAAGLPACPRLAAAEGQSERLWSITGNEAAGLGAVRGGI
                     RFVAAYPITPGTEVLEWLAPNLAKLGGVLVQAEDELASINQIIGASYAGVPSLTATSG
                     PGLALMTESLGLAVASETPITVVNVMRGGPSTGIPVKSEQSDLNIALYGLHGDAPHLV
                     VAPNSLADCAFSTQWAVHLADSLQTAAIVLSDQSLGQSRATIAPPLDPGFRAIRLMPE
                     GEASERYRRYTNTASGVSPMAVPGMKGYQYTADGLEHNEYGTPSSAAADHSAQLDKRL
                     RKLAVHDYGQHWADIEGDGDIAVLTWGSTTGPVREALERFRASGGRARLVSIRLISPV
                     RPEQLAAALAGVARVLVVEQSHGAQFHRYLRAHYDLPGSVRAFHRPGPLPIRPNEIFR
                     QLADWS"
     gene            17915..18982
                     /gene="had"
                     /locus_tag="P5537_07045"
     CDS             17915..18982
                     /gene="had"
                     /locus_tag="P5537_07045"
                     /EC_number="1.1.1.368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0019439 - aromatic compound catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-hydroxycyclohex-1-ene-1-carbonyl-CoA
                     dehydrogenase"
                     /protein_id="HRV77835.1"
                     /translation="MSTKPYRWMMVEPGRPMVRTEFEIGELAADQVVVEVAGCGVCHT
                     DLGYYYDGVRTNQALPLALGHEISGRVVGAGSAAGQWVGRAVVVPAVMPCGTCELCTS
                     GHGTICRAQVMPGNDIQGGFASHIVVPARGLCAVDEQRLAAAGLQLADVSVVADAVTT
                     PYQAVTQAGVEPGDVAIVIGVGGVGGYAVQIANAFGASVVAIDVDPAKLELMSKYGAA
                     LTLNAREVTGRDLKKAIEAHAKANGLRTTRWKIFECSGSGAGQTNAYSLINHGATLAV
                     VGFTMDKVEVRLSNLMAFHARALGNWGCLPEYYPAALDLVLDGRINLANFVERHPLAQ
                     INEVFEAAHAHKLTRRAILTP"
     gene            19035..20168
                     /gene="oah"
                     /locus_tag="P5537_07050"
     CDS             19035..20168
                     /gene="oah"
                     /locus_tag="P5537_07050"
                     /EC_number="3.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0019439 - aromatic compound catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-oxocyclohex-1-ene-1-carbonyl-CoA hydratase"
                     /protein_id="HRV77836.1"
                     /translation="MKETTQRVIDQTAPKHLVDHNLVPETVVPGVIYEKRPARNLQGE
                     VVPGLYNAWIWLDNPKQYNSYTTDMVKGLILAFRAASCARDVATVVFTAVGDKAFCTG
                     GNTKEYAEYYAGNPQEYRQYMRLFNDMVSAILGCDKPVVCRVNGMRIGGGQEIGMAAD
                     FTVAQDLANFGQAGPKHGSAAIGGATDFLPVMIGCEQAMVSGTLCEPFSAHKAYRLGI
                     SSQIVPALKVDGKFVANPLVITDRYLDEFGRIIHGEFKTGDELAAGKELLKRGEIDLS
                     LLDEAVEKLCAKLISTFPECLTKSFEELRKPKLDAWNRNKENSRAWLALNMMNEARTG
                     FRAFNEGNKDTSREIEFTDLRQALAVGTPWTPELIESLMPGAK"
     gene            20168..20944
                     /locus_tag="P5537_07055"
     CDS             20168..20944
                     /locus_tag="P5537_07055"
                     /EC_number="4.2.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclohexa-1,5-dienecarbonyl-CoA hydratase"
                     /protein_id="HRV77837.1"
                     /translation="MGEAINPLKAWLERDGGLLRLRLARPKANIVDAAMIGALQEALG
                     AHLGSPALRAVLLDAEGPHFSFGASVDEHMPEQCAQMLKTLHALVRQMLDSPVTILVA
                     IRGQCLGGGLEVAAAGNLLFVAPDARLGQPEIRLGVFAPAASCLLPPRVGQSRAEELL
                     FSGRSIDGAEAFRIGLADVLADDPEAAALKWYDEHLAASSASSLRFAVRAARCDHVPA
                     IKQKLETVEAMYLEELMASHDAVEGLRAFLEKRSANWENR"
     gene            20947..22107
                     /gene="bcrC"
                     /locus_tag="P5537_07060"
     CDS             20947..22107
                     /gene="bcrC"
                     /locus_tag="P5537_07060"
                     /EC_number="1.3.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018522 - benzoyl-CoA reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="benzoyl-CoA reductase subunit C"
                     /protein_id="HRV77838.1"
                     /translation="MSTADIIARCEALYEDLDFTAARKWKEADPSRKVIAYMPVYVPR
                     EIIHAAGMLPLGIMGGGDGLEVIHGDAYYQSYICRIPRSTIELGLSKRMDFVDGMLFP
                     SICDVIRNLSGMWKLLFPGKYVRYFDVPQNYKDDVGGSYYTNELNELREGLEHLSGRK
                     ITDDALRASIEVYNENRKLVQAVYGMRSREPWKVPSSEVYLLMRAGLVVPVEEHNQIL
                     RDYLAAAEKVQASKRDNCRVVINGSFCEQPPLNLIKSIELAGCYIVDDDYIIVHRWLR
                     NPVSTSGDPMQNLSLAFLHESIATAAKYDDKEEDKGKYLLEQVRSNAAEGVIFAAPSF
                     CDPALLERPMLADRCSEHNVPYISFKYAENSGQMQPIREQAGTFADSIKLWS"
     gene            22110..23408
                     /gene="bcrB"
                     /locus_tag="P5537_07065"
     CDS             22110..23408
                     /gene="bcrB"
                     /locus_tag="P5537_07065"
                     /EC_number="1.3.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018522 - benzoyl-CoA reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="benzoyl-CoA reductase subunit B"
                     /protein_id="HRV77839.1"
                     /translation="MSAATSPEVIKEPSMVKQKEMIAGNYDRLTSTKESGEKVVSTFV
                     PGNLNELIMCFDMVNNLPETNAIQNGMRKVSGGMIMDAEKAGHSEDVCTYVKADIGMM
                     GRGNIAPNGKPMPAPDMLLLSYTGCFTFMKWFELLRHEYKCPTVMLQIPYQGDGKITK
                     NMRDFVVKQLKEEVIPMFEKVSGVKFDIDRLREYLKNSAKAEDNLVWVLESAKNRPSP
                     IDAYFGGVYYIGPMFTAFRGTADAVEYYDLVRKEIEQRIREGKGPITPEGDMKEEKYR
                     LVVEGPPNWTSFREFWKLFYDEGAVVVASSYTKVGGLYDQGFRHDPNDPLGTLADYCL
                     GCYTNNNLPQRVELLEKYMNDYQADGLLINSIKSCNSFSAGQLLMMREIEKRTGKPAA
                     FIETDLVDPRYFSHANVKNRLESYFQMVDQKRSGASLAAA"
     gene            23419..24738
                     /gene="bcrA"
                     /locus_tag="P5537_07070"
     CDS             23419..24738
                     /gene="bcrA"
                     /locus_tag="P5537_07070"
                     /EC_number="1.3.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018522 - benzoyl-CoA reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="benzoyl-CoA reductase subunit A"
                     /protein_id="HRV77840.1"
                     /translation="MECFVGIDLGSTTTKAVVMDDKGQVLGRGITNSRSNYDTAARVS
                     KLEAFIDARLSLIRRELEKVPAVADRVDEILSGLTRNFRREQFVEQLGDLEQTCVANV
                     EGPRFAGKEKAIIGALTEVFRRLREEEADKLFAPTAQRKSDFFRDLAGSRFMQIGEEV
                     ARDAGVPFDHLLHMYDKSIIEVENRPPSADMNRKFRTAMERVRGELSGADLDTAALGA
                     PIDAALDVDMVERYVVGTGYGRVRLPFPKEHIRSEILCHGLGAHLMYPKTRTVLDIGG
                     QDTKGIQIDEKGIVVNFQMNDRCAAGTGRYLGYVADEMNMGLHELGPLAMKATKSIRI
                     NSTCTVFAGAELRDRLALGDKREDILAGLHRAIMLRAMSIISRSGGITDEFTFTGGVA
                     KNEAAVKELRQLVKENYGEVKINIDPDSIYTGALGASEFARRAVVEA"
     gene            24741..25589
                     /gene="bcrD"
                     /locus_tag="P5537_07075"
     CDS             24741..25589
                     /gene="bcrD"
                     /locus_tag="P5537_07075"
                     /EC_number="1.3.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018522 - benzoyl-CoA reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="benzoyl-CoA reductase subunit D"
                     /protein_id="HRV77841.1"
                     /translation="MTITAGIDIGTGAVKTVLFRVEGDKTEWLAKRNDRIRQRDPFKL
                     AEEAYHALLEEVGLKASDVDYVATTGEGESLHFHTGHFYSMTTHARGAVFLNPEARAV
                     LDIGALHGRAIRNDERGKVETYKMTSQCASGSGQFLENIARYLGIAQDEIGSLSNQAD
                     NPEVVSSICAVLAETDVINMVSRGITAPNILKGIHISMAGRLAKLLKSIGAREGVVLC
                     TGGLALDEGLLNTLNESIKEQKMAVTAFNHPDSPFAGAIGAALWGAFRHEKLARLGGQ
                     QLAAAA"
     gene            25615..25857
                     /locus_tag="P5537_07080"
     CDS             25615..25857
                     /locus_tag="P5537_07080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhL family 4Fe-4S dicluster ferredoxin"
                     /protein_id="HRV77842.1"
                     /translation="MALLINDDCTACDACVEECPNEAITAGNPIYVIDPNKCSECVGA
                     HDEPQCVLVCPADCIKPHPDYRESQDELQAKYDSLH"
     gene            25914..26378
                     /locus_tag="P5537_07085"
     CDS             25914..26378
                     /locus_tag="P5537_07085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HRV77843.1"
                     /translation="MTANTEIKLRPLAAGDLAAVTRLDATNGGESRAGFFERRLQAEQ
                     QSPAGFFSCVAERGGEVAGFLLGHLLDGEFGGLERVAVLDAVAIDPAAQRQGLARKLV
                     GEFDRNARERGASEMRTQAQWDRPGLVEFFSAAGFRLSPRLVLERPTEYVNF"
     gene            26414..26959
                     /locus_tag="P5537_07090"
     CDS             26414..26959
                     /locus_tag="P5537_07090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HRV77844.1"
                     /translation="MTTRPHPTTKQLLDQFNTEPDYSDASQDDAEALSRDRIPVRSLT
                     AADFDAVVRIDRRSTGHDRSAYYRRKFDEALGESGVRVSVVAEQDGMVAGFLMARVDF
                     GEFGRAATAAVIDTIGVDAAASGKHVGRALVSQLLANLTSLHVESVRTEVEWNRFDLL
                     RFLDRCGFRPGQQLSLSRPLV"
     gene            27035..27745
                     /gene="fabG"
                     /locus_tag="P5537_07095"
     CDS             27035..27745
                     /gene="fabG"
                     /locus_tag="P5537_07095"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase FabG"
                     /protein_id="HRV77845.1"
                     /translation="MGFTGQLAGKVAIVTGGARGIGRTITDALVARGAQVHVFDMTDS
                     NESAGVLHRVNVADAQSVADAVAQLPEPATLLVNNAGITRDRSLLKMSDDEWRSVLDV
                     NLSGAFHMVRACAPGMIAAGSGRIVNITSINGLRGKFGQANYTAAKAGMIGLTKTAAR
                     ELGPKGITVNAVAPGMVMTEMARALPAEVLERALQESVMRELATPEDIAAAVVFLLSD
                     MARMITGEVIRVDAGQYV"
     gene            27932..29080
                     /locus_tag="P5537_07100"
     CDS             27932..29080
                     /locus_tag="P5537_07100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HRV77846.1"
                     /translation="MKLKKTLFVALGLAFAAGAAHAQLKVGITVSATGPAASLGIPER
                     NTVELMPKEIGGQKVTYIVLDDASDTTSAVKNIRKLVSEDKVDVVLGSTTSPNSLGMI
                     DVAAESQTPMIAWAASSRIVEPVDDKRRWVFKTPQNDSHMSTAIVSHMTSNNVKNVAF
                     IGFADAYGEGWYEQFKSVAEARGIKIVANERFTRTDTSVTGQVLKMMAAKPDAMFIAG
                     SGTPAALPQKTLKERGWSGKVYQTHGVANNDFLRVCGADCEGTLLPAGPVLVAEQLPD
                     DNPVKASAMTYIKAYEAAHGKGSVSTFGAHAWDSGVMLQAAVPEALKKAQPGTAEFRA
                     ALRDALENMKEVPAAHGVFTMGPNDHLGLDQRARVMVQIQKGAWKLVQ"
     gene            29195..30232
                     /locus_tag="P5537_07105"
     CDS             29195..30232
                     /locus_tag="P5537_07105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HRV77847.1"
                     /translation="MDFQIALILGQDGITNGAIYALLALALVLVFAVTRVIFIPQGEF
                     VAYGALTLAMIGNNVFPATAWLLLGAGIAVAALDGLGALRAGQARKLPRVLAVNVGYP
                     LAVIALLRLLPLAELGLAVQILLAMLIVVPLGPMMYRIVYQPIAEATVLVLLIVSVAS
                     HVAMVGLGLLFFGAEGYRTPPLSDARFDLGSLSISGQTIWVVAASIVLIVALALFFGR
                     TIYGKALRATAINRNGARLMGIPPALAGKLTFLLAALIGVLSGVLISPITTIYYDSGF
                     LIGLKGFVAAIIGGLASYPLAAFGAVLVGLLESFSSFWASAYKEVLVFTLIIPVLVWR
                     SLTSHHVEEEE"
BASE COUNT         4672 a        10008 c        10721 g         4732 t
ORIGIN      
        1 ccgcgacggt tcatgtagga gcgccggcag gcgcgaatgc ggcttcgctc aggccgcctg
       61 tgccttggcg agcttgccga gcaggcgctg gcgggtcttg tcgacgccga ccacgaagcg
      121 gttgtggcgg ccgcgggcga cctcctcgag ggcgtcgcgg gcgctgaact cgaacaccac
      181 cgccgggccg ttgacctcga ccagcttgac ggtgatctcg atccacatgc cgagcagggt
      241 ggcgccgacg tggtcgagct cgacgcgggt gccgaccgag tccttgcctt cgccgatgtg
      301 ctcgagcagc aggtcgcggc agcacacctc gatgtcgtag agcagcgccg gggtggaata
      361 gacgcggcac tcgtcgccca tgaaggcgat cgtgcgtgca gcgtcgatgt cgtacttgcg
      421 ggtgaggctg aggccggctt gaagggtttc gctcatcgtc tgtctccgtt tgcgggtggt
      481 cgggtttgtg ttggtgctgc ggggtggatg gatgcgggaa tcaggatcgg ccgaagtggc
      541 gacggatgcg ctcggcgtcc atgcgcgcct cgacgtagcg cacgagcgca cgggtgccgc
      601 gcgcgacgtt gcggaacacg cacacgccac ggtccatcag gccggcggcc atggcgtcgt
      661 agaggcggcc ggcgtcgacg accgcgacga tcggcttgtc ggtgcgggcc accagcggcg
      721 gcagggtatg caccgtactc tcggggtcgg agaggtcgta gccggggcgt agcctgctct
      781 gctcgagcgc gcgcaccatg ggcgcggtgg ggtcgaggcc gaccacgacc gcgtcgaccc
      841 cggggtcgtc cgccatcgcc gcggtgatgc gcacgtgggc gtcgtcatcc gcgcccgggt
      901 tcatgtcgag cgggttgcgc acctcgacca gggcggcgag cttcttctcg gccagcaccg
      961 cctcgatgcg ggcgaaggtg tcggccgaga gcgtggccat gcgcatcgag aaggtcgcgc
     1021 cgacgctggc gtccgcggcg ctgaccgcct cgaagccggc gccgctggcc gcggcgaggc
     1081 ggtcgccgcc gatgcgcttg gcgtgcaggg tgccggccat gtagaagagg tcgtcgaaga
     1141 cctcgacgtc gtcggtgacg atggcgccgg cctgggcgag caccgcggcg aacagcaccg
     1201 ggtcgccggc gatcgaggcg gtgtggccca tcacgccggc ctggccggcc tcgctgcgcc
     1261 cggacttgta caccacgacc tgcttgccgg cgagcaccgc gcgccgcact gcgcgcgcga
     1321 aggccaggcc gtcgaggtcg cggaagccct cgacgtagat gccgatgctg tcgacgtcct
     1381 cgcgggcggc gaaccacgac agcaggtcgc cgtgggtgag gtcggtctgg ttgcccatcg
     1441 cgatcatgta gcgcgggtcg agccaggggt tgtgcgacag gcgggtgatc atgaaggcgc
     1501 cgctctggct cagcatgacc gcgcggcgct cgggcacctt ctgcggcttg ggcaggcgct
     1561 cgagcgggat gaaccaggag tcgtagcggc ccgggtgcga gaccacgccc aggcagttgg
     1621 cgccgaggaa gatcggcccg ccatcgccgc gcgcgtgtgc ggcgttgatg cgggccgcca
     1681 gcgctgcagc cggctcgcgg ctcttcgcgg tctcgccgag tccgcccggg atcagcatga
     1741 cggcctcgac ggtggcggcc gcgatgatct cgtcgaccag cggatagacc gcgtcggcgg
     1801 cgaccgccac gatcagcagg tcgagcttgc cctcgatcgc ggcgaggttc tcgatgcagg
     1861 cgacgccatc gatctcgccg ccgccggggc ggatcacgca caggcgctcg ggtgggcagc
     1921 cgctgccgag caggttgcgc aggatgatgc ggccgaagtt catgccgctg gctgaggcgc
     1981 cgacgatgcc gatgcgctcg gggtggagca ggcggtcgat cttgtggatc gggcgcgcca
     2041 cgcgcagcag cgggggggcg ccgacgctgc agcgcgcggc gacgatctgc accgcctcgc
     2101 cgtcgcaggc gcagtcgagc acgagctcgt gcagcgcgac ctgcgcnnnn nnnnnnnnnn
     2161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2221 nnnnnnnnnn nnnnnnnnnn nnnnnnccgc ctcgccgtcg caggcgcagt cgagcacgag
     2281 ctcgtgcagc gcgacctgcg cacccggggt gtcgggcagg ccgcccgcag ccagctgcag
     2341 cgcggcctcg aagaggcggg cgagctccgc ctcgggggcc tgcacgccgc ggcgggcggc
     2401 gagggcggcg atgcgctgcc aggcgatcgt gcggcggaag cgcgcgagga agtccgcgcc
     2461 gtcggtgagc tcgactgccg catgcaccgc cgcgcgctcg cgcgcgaaat tggcggggtc
     2521 gagtgcggcg tcgaggccgc cggcaccggc gccgagcacc aggccgaact cgcgcgtggc
     2581 gtggacgcgg atcgacagct cgatcgcgcc ggcgggcgcg ctggcggtgt gcagctcggc
     2641 ggcggcgagc aggcgggcga gctcgccggc gtcgagcgtc gcgcgcccgg ctgcgcgcgc
     2701 cgtgtggtag atccgcgcgg cttcgcctgc cgcagggctg gcggcgtggc ttcggacttc
     2761 ggtcatcggg tgtctccgtc ttcgttcttg tagtgagggc cggggggccc ggcgggtggc
     2821 ccggtgccgg gatcccgtcc cggcaccgga cgatctcaga cctcgctggc gacgcgctcg
     2881 cggcggtcga tcacgcgctt ggccttgccg acctgggtgc gctcgatgct gtccgggtcg
     2941 aggacctcga tctcggcgct gatgccgacg aagctcttga tcgcgtgccg gacttcctcg
     3001 ccgatctgcc ggcgcaggcc ctggccgatg cggtcggcga gctcggggcg cagctcggcg
     3061 cgcacagtga gctggtcgag gtggccttcg cgcgtgagca cgagctggta gtggccgcac
     3121 agcttgtcgt ggcgcagcag cacctcctcg atctgggtgg ggaagacgtt gacgccgcgg
     3181 atgatcagca tgtcgtcgct gcgcccggtg atcttgtcga tgcgccgcat cgtgcagccg
     3241 gtgccgggca gcaggcgggt gaggtcgcgg gtgcggtagc ggatcaccgg catcgcctcc
     3301 ttggtgagcg aggtgaacac cagctcgcca cgctcgccgt cgggcagcac ctcgccggtg
     3361 acgggatcga tgatctcggg gtagaagtgg tcttcccaga tgtgcgggcc gtccttgtgg
     3421 ccgacgaact cgcaggccac ccccgggccc atgacctcgg acaggccata cacgtcgatc
     3481 gcgtcgatgc ccagcatgcg ctcgatctcg gcgcgcatct ggttggtcca cggctcggcg
     3541 ccgaacatgc ccagccgcag cgtggtcgag gaagggtcga gccccatgcg ctgcatcgtg
     3601 tcggccagcg tcagcatgta ggacggcgtg gccatgatca ccgtggggcg gaactcctgg
     3661 atgagctgga tctgcttctc ggtgttgccg ccgcccatcg ggatcaccgt ggcgccgagc
     3721 gcctcgccgc cgtagtgggc gccgaggccg ccggtgaaga ggccgtagcc gtaggagttg
     3781 aggatgatgt cctcgcagct cgcgccggcc acgcgcagcg agcgcgccat gaccgcggcc
     3841 cagcgctcga tgtcaccctt cgtgtagccg accacggtgg gacggccggt ggtgccggag
     3901 gatgcgtgca ctcgcaccac cttggacatc ggcaccgcga acaggccgta agggtagttg
     3961 tcgcgcagat cctgcttggc ggtgaagggg aactttgcca ggtcggccag gctctccagg
     4021 tcggacggcc gcacgccggc ggcctcgaag gcgtggcggt agtgcggcac gttgtcgtag
     4081 gcgtgctgca gcgaccagcg catgcgctcg agctgcagcg cctgcaactc ggcgcggctc
     4141 atccgctcgg gggtggcggg cttctcattg ctcatcggcc tgctccgcga tcttgcgcac
     4201 gaagcgcagg ttctcggcca ccttgttctg gatgtgctcg acctgctccg ggctgaggtg
     4261 gcggaagcgc cccatcgcct tgaggtagtc ggccaccggc agcggatcat tcaccgggcg
     4321 ggtgaagtgc agcccgctct cgggggtgta ttcccacagg gtgacgaagt tcgactccac
     4381 cgccttgcgt gcgacctcga tgttgagcgc gctctggaag cgccagccgg tggtgcaggg
     4441 cgaatacacg tgcaggtagg cgaagccgcg ctcggaggcg gcgagcgcct tgtcgagctt
     4501 gtcgtagaga tcctccatgt aggcggtcga cgcggtggcg acgtactcgc agcggtggtt
     4561 gatcatgatc atcggcaggt tcttggcgtc ctgcgacttg ccgcgggtgt gctcgccgac
     4621 cggggtggtc gaggtccatg cgccgtaggg cgtgcagctc gagcgctgca tgccggtgtt
     4681 catgtagccc tcgttgtcga ccaccatgaa gaggatgcgc tcgccgcgct cggccgcgcc
     4741 cgacagcgac tggaagccga cgtccgaggc gccgccgtcg ccggcgatcg ccatcgtggt
     4801 gaccttgcgg ccgacgcgct cgtactggcg cttgaccccg gcgagcatcg ctgcggtgtt
     4861 ggtgagcagc gggtggaaga ccggcacctt ggtgccggtg gtgccgttga agcccaccga
     4921 gcccatgccc ggcacgcaac ccggcggggt ggcgagcacg gtgtcggggc cgacgcggcg
     4981 cagcgcgtgg cgcatcagca gctcggtgtt gcagccctgg cagccggcca ggccgggggc
     5041 gaagaggtct tcccagctgc cgacctcgtt gtagatgcgc gcggtggtga tgtggcgcag
     5101 cgccccggtg gggcaggcgg gcacgcaggc cggcttgccg tcgcaggtgt cgcacttgct
     5161 gacgcggccg ctgtgctcgt cgagcgcgat gccggcgtag ctgcagccga tggtgcacag
     5221 caggcagtcg acgcacttcg aggcgtccca gtcgatgacg ccggtggcgc cgttcttgcc
     5281 gagcgcgccc gccgggcaca cggtgacgca cttggggtcg gcgcactggc ggcagagcgc
     5341 gagctcgaac tcgcccggac gcggcggctc gatgctggcg ccgccgctgc gcacgatctg
     5401 gatcaatgag cgcgtggtgt cggtcgagtc gaacttgacg ctcgcgcacg ccgtcatgca
     5461 tttgccgcag ccgtcgcact tggcgggatc gaaggcgatg gtggagtagg cttgtcccat
     5521 ggtcttcccc ttagcgccag agctgcgaca tgagctcgcg gccggtggcg agcggctgcg
     5581 cgaagaagcg ttcgcgcagc ggtccgagat cggtgcggcg gacgatgagc tgggccatca
     5641 cgccggcatc gaagaattca ttcaccccga agatgccggt caggcgctcg tcgcggtcga
     5701 acaccgcgcg caggtagcgc ccgctcgcgg cgtcgaagcg cacctgcgcg cgtccgccct
     5761 cgggaactgc ggcgctgccc accgagatcg cgtggcggcc gaagaagtgg taggtgttga
     5821 gcggcacgcc gcccgggtag ggcttgagcc cagggtcgcc cgccatcgcc atgccggcga
     5881 tgcggccctg cacggtggcg tcgggcagga tggcgttcat caccggggtg ccggtgaaga
     5941 agccgcgcgc ctgcgcacag tcgccggcgg cccagacgtc gtcgacgctg gtgcgcatgc
     6001 tgtcatcgac caggatgccg cgctcggtgg cgatgccgct gccatcgagg tagccgagct
     6061 ccggacgcac gccgaccgcg accagcagca ggtcggccgg gatggtgtcg ccgttgtcga
     6121 gctgcagggt cgcgccgtcc ggcccgggct cgaggccgac cacgcggtgg ccggtgcgga
     6181 tcttcgcgcc gttgccgagg aaggcctgct cgatcatgcc ggcggcgacc tcgtcgaagt
     6241 agccggaggt gagctgcttg ctcatctcga cgatggtgac gctggccccg gccttgacca
     6301 ggttctcggc ggcgtgcatg ccgaccaggc cggcgccgag cacgaccgcg ttcttcgagc
     6361 ccgccatggc cgcgcgtagc cgggtggcgt cgtcgagcgt gcgcagcacg tggtagtcga
     6421 cgcggtcgat gccggggatg ggcggcacga ccgggctggc gccggtggcg agcagcagct
     6481 tgcggtaggc gatcgtgctg ccgtcggcaa ggcgcgcctg gtgtgcagcg gggtcgatgc
     6541 cggcgagcgc gcagccgctg cggtagtcga ccttgttgtg tgcgaagaag tcgtcgtcgc
     6601 gcaggtagac gcgctcgggc gtcgagcgcc cggagacgac gtagggcagc acggtgggcg
     6661 agtagggccg gtgcgggtcg cgggtgacga cggtgatggc gccctcgccg tcgtgcatgc
     6721 ggatcgcgtt gatcgcctcg agcgcggcgt ggctgctgcc ggcgatcagg tagtcggtgg
     6781 tgtgcatggt ggtctcctct gtccctggcg ctcagtcttt cgcgttcagc cacaccggct
     6841 cgtcggcggc cggccgctcg agcagggcgc gcgtctcggc gatgacgcgg tggaaggtgg
     6901 cgacggtgag gtcggcgccg gcgaggccgc cgatgaagct ctgcgcgggc agctggcgac
     6961 cgaggcggta gagcacggcg agggtctcct ggaacatcgg cccgcagttc cagcggaagt
     7021 tgaccgagcg gtccaccacg ccgagcgcgc gcacgtcgcg cagggcatgc ttgagcgcct
     7081 cgaccgggaa ggggctgaag gtcttgatct tgatgagccc gaccttctcg ccggcggcgc
     7141 gcgcctcgtc gaccgcgtcc ttggcggcgc cggtcatgct gcccagggtc atgatcgcgt
     7201 actcggcgtc atcgagccgg tactcctcga ccagcggggc gaagcggtgg ctgtcgccga
     7261 agcggcgcgc ccagtcctcg tgcatctcgg tgatcacgcg cagcgcgttc ttcatgccgg
     7321 cgcactggcc gcggcggtag cgcacgaagg tctccggccc ggtgccgccc gagccgccgg
     7381 tgagcggatc gaccgccatc gggcgcagcg ggtcgagggc gacgtgccag ttgacgtcct
     7441 tgcgccccat gaagtcgtcc acctcggcct ggtcgggcat ctcgacgcgc gcggcgccat
     7501 aggacaggta gttgccgtcg aggcagacgt tgaccggcag catgacatcg tggtgctcgg
     7561 cgaggcggaa ggccatcacc gtggtgtcga gcacctcctg caccgtctcg caataaagct
     7621 ggatccagcc cgcctcgcgc accgtcatcg cgtcctggtg gccgccccac accgactgcg
     7681 gggtgatgcc gtcgcgggtg acgatggtca tcaccatcgg caggcgcatg cccgaggtgc
     7741 ggaaataggg ctcgaacatg aaggcgaggc ccgggccgca ggtcgcggtg taggtgcgtc
     7801 cgccggcgag cgcgccgccc tgcagcaccg agagcaccga gtgctcgccc tcggcgtcga
     7861 cgatgtcggc gtccatgccg ccgtcggcga tgagcttggc gagcttctcg accagcgagg
     7921 tctgcggcgt gatcggatac accgcgacca tgtcggggcg ggcgagcgcg acgccgagcg
     7981 cggcggcctc gttgccctcg accagcatca gctggggggc gcgttccgcg acggtgtgcg
     8041 ccgcggcttc ggtcgtggtg gtgttcattg cgcctccggg accatgatga tcgcccgctg
     8101 cgggcattcg tgcgcgcaga tgccgcagcc cttgcaggtc ttcaggttga agtcgaacca
     8161 cgcggcgtgc tcctccacgc actgcaccgg gcagtacagc cagcacaccg cgcacttgac
     8221 gcatttgtcg cgatccacca ccgggcggaa gctgcgccag tcgccgggca gcatcggggt
     8281 gagctcggtg gcgaccggac agaggtcttc cggcacgccg tgctgcttga ggtgccaggc
     8341 gggatagcgg gtatgtcgct cgctcatgct gtgagcctcc gttcgagggt gtgcaccgtc
     8401 gtctcctcgt agccgcgctc cagcgcggtg aggttctgcg cgaggccggc gtcgcggaaa
     8461 tccgattgct cgatcacctt cttgagcgcg gccagcgaga cctggccggt ggtgcgggcg
     8521 aaggcgccga gcatcagggt gttggtgatc gggcggccga agatctcggt ggcgatgcgg
     8581 accgcgtcgc acaggccgac cgtgccgacc gtgtcggcga ccgcgacctc ctcgagcggc
     8641 cgcgaggtcg cctgcaccat cgccccgccg ggcttgaggc cggcgaagat gtcgaccgtg
     8701 cgtgcgaggg tggggtcgac gcagatgatg cagtcggggg cgtagatgtt ggtgagctgg
     8761 cggatgggcg tttcgctggc gcggatgaag gacaccaccg gcgcgccgcg acgctcgaag
     8821 ccgaaggcgg ggatggagac ggcgtacttg ccgtcgaaca cgagtgcggt cgcgagcagc
     8881 tgggccgcaa gcaccgcgcc ctgcccgcca cgaccatgaa tcctgacctc gtacatgcgc
     8941 tttgctcctg atgtcggcgt cggtccgcag gggccgccgc cgcggggtgg agggaggggt
     9001 tcagttccag cccggcttga cgccggggtg ggagtagccc ggggtgcgcg ccggcacctg
     9061 ctgcagcgcg aagccctggg tgtaggcgat gcgggtgatg agggcgagct tgaaaagcca
     9121 gccgctggcg gcgaccgcga tgcccgcgag cgcgagcagc gcggtgccga agctgccgcc
     9181 cgccaccagc gcgagcacca gcacggtggc tggcagatag tggccgagga ggaggaagtg
     9241 gcggtcggtc tcgcgcagcg cgcgcagggt cttcaacggt gcgttgttcg ggcgggcgag
     9301 gtgggcggcg tagcgcctcg acagccacaa gcgcagcacc accagcacca gcagcgggag
     9361 ggcgaactcg gccccgggcg agccggcgag cagcggcgac agcagcgcga gcatgcctgc
     9421 gccctcggcc agcccggtga cgacgatcag cggcagcagc gccggctcgc gccaggccgg
     9481 gatgccgcgc gcggcctgca ggatgcgcgc ctggcagtac aggaagatca ggccgatcag
     9541 cgccgccagc caggcgaaga acagccagcc gctgagcagc gcgacgaggc cgcacaggaa
     9601 gagcgggccg gcgacgatcg cctcgcgcgt catccacgaa gtgcgcgcat ggaagaagac
     9661 gttgagcgcg cgcagcgggc ggccgatctc catccacacg cagaacaggc cgacgccgat
     9721 acaggcgagc gcgaggaaga gcggcaggcc gatcgcagtg ccgtggccgc tggccgcgat
     9781 cgcgctccac agcagcagtc ctgtgccggt gccaccgccg atgaagttgc ccgcggcacg
     9841 ctcgtcccag aagggctgca gttcgggttc cacgcctctc attgcttttt ctcccagaga
     9901 tagaagaagc cggggccggt gccgagctcc tcgtgcatgc ggaaatgctc gttctcgcgc
     9961 agcaggcgcg aggccttgct gtcggggtct tcgatgtcgc cgaaggtgag cgcgctggcg
    10021 atgcaggcgt tggcacaggc cggggtggcg tcgggatcga cgccgggcac gaggccgtgg
    10081 gcgtggccgt agtcgatgcg gtcggagcag aaggtgcact tggtggcgac gccgatgcgc
    10141 gccgggtccg cacgcttgac ctcgttgggc atcctgccct cgccataggc cggggtgtca
    10201 cgggtgacct tgtagcgcgc gttgtacgga caggcgaccg aacagtaggc acagccgatg
    10261 cagaggtcgt agtcgatggt gaccagcccg tcggcgcgct tcttggtggc ggtggtgggg
    10321 cacaccgtct cgcagggcgg ctcgtcgcag tgctggcagc cgaccgggac gaagctgcgg
    10381 gtgacgtcgg ggaattcacc cgcctcgacg tcgagcaccc agcgccattg cacccccggg
    10441 ggggtggcgt tggtgtgctt gcaggcggca gtgcaggtct ggcagccgac gcagcggcgc
    10501 aggtcgacca ccatggcgta gcgggtcatt gggtacctcc gatgcgcttg atcgacaccg
    10561 gcacgatgtc ggcggccgag ccggtggcgt cggtcaggtc catcagcatc ggcaccaggg
    10621 cgttcatgct ggggacgtcg aagtccttcg cgtagggcgt gatccaatgg tcgaactggc
    10681 ccaccatgag cagggtgtcg gggcggatgc cctggcgcag cacgacgcgg ccgcgcgtct
    10741 cgcgcagcgg cgagcgcacc tcgacgaggt cgccgtcctc gatgccgagc ttgcgcgcgg
    10801 ccgtcgggtt catgatcacg ccgcggtgtc ccttcacgtt ggcggccacc tcgcgcacca
    10861 tctgcaggct gacgttgccg ccccaggagt actgcatgct gcgtgcggtg agcagccaga
    10921 acgggaagtc ctcgtcgcgc ccgcccaggt tggagatcac cgcatgcttg atgaggtggg
    10981 agaagtcgtg gaactcgggc agagggcggt actcggtgag ctggcggtcc caccagtcga
    11041 tgccggattc gtgcaggcgg cggccgagct cctcgccgat gcggtagatg cgttcctggt
    11101 agggcatctc gaagcgcagg ccctggtcca ccaggtgcgg gtagagatac cactgcaggc
    11161 gcggatactc gatggtgcgg aagccgtgct ccttccacca ctccaggcca tgatcctcgg
    11221 cgccttcggt gagctcggcg ctggccgcgc ggcagctcgc gtcccagatc tcctcgactc
    11281 cgtaggcgcg gtcgggctgc agcgagaagt cgtagttcgg ccccttcagc ggcacgcccg
    11341 cggcgccgcg gttgattgcc ttgttgtaga tgtcgaggat gcccgagcgg cgggcgagct
    11401 cggtgctgat ccaggtgaag tcacgcgtgt cgccctgcgg cggcaccgcg ggctggcgca
    11461 gcgcgaagcc ctggtggtcc cagaactgct cgacgtactt ggtgccgccg atgcgcagca
    11521 tctgcaggcc ttcgaggtcg gtgcagtcgg gcagcaggat gtcggcgaag tggttggtct
    11581 cgtcgcgggt gtagctgaag gcgaccacga aggggaactt cgccactgcc tcggccacct
    11641 gcggcgtgtc ccagaacgag atcaccggat tggtgcggta gaagaaccag acgtcgggct
    11701 gggtgggctc ggggaagctc tcgaagccgt ggcgctgctg catccaggcc aggtgggtgg
    11761 ggccgagcgc ggcgctccag gccgagttgg ccaccagcgg caccagggtg cggttggcgt
    11821 tgcggatctg cgggcgggag atccagtttt ccttgtcggt cgggttgaac gggtagtcca
    11881 tgaacccgtc gacgcccggc ttggcgctgc tctggcggtc gttggccggg cggttcaggc
    11941 gcaccgcggt gccgatggtg ccgccgggca cgtcgagcgc gccgaccagg caggccatca
    12001 gggtgcgcgc ccagcagcag tcgtagccgc cccagccgtt attcaccgtc ttgccgagcg
    12061 tgaccgccac cgggcggtag ggcagggcgc ggccctcgat ctcgatcgtg gcgccgatct
    12121 cggcgtggtc gaggtattcg ttggcgacgc ggcggatggt cgccgccggc acgtcgcaga
    12181 tgccctgcgc ccattcgggt gtgaagccgc gctcgtggtc gagcagcttg ccgaaggcgc
    12241 tgcgcaccgc gacgccctcg tgggtgacga gctccgcgtc gggcaggacc tccaggccgg
    12301 aggcgatgaa gtcgccgtcg agcgcggggt cgatgtccgg cgtgtcgaac gcgaccgccc
    12361 tgcctgtctt caggtcccac accagcggct tgcgggtgtc ggggtcgcgc aggtagaagc
    12421 cgttcggcgc caccaggtag ggcgatgcgg tgcggtgctt gaggaagtcg atgtccagcc
    12481 ggctgcgcgc gttctcgaac agcatcacgt ggatcagcgc gtgcatgcag gcggcgtcgg
    12541 tcttgggctt gatcggcacc cactcggcgg agcagccgcc ggtgacggag aggtgcggct
    12601 cgaactgcac gcgcttgacg ccctgctcga cgcgcgcggc ggcgtggcgc cagatgccgc
    12661 acacgccgcc ggaggcctcg atgttgctgc cgaaggacag gatgtacttg ctgcgtggcg
    12721 tgtcgggaca gacgatgaag gcgcggtgcc agagctcgcc gtagaggtgc tcggagtggt
    12781 agcacttgac gccctggccg ctgccgaagc tcatgtccac cgggccccag gccgccagca
    12841 gggcggggaa ggtacccatg taggcggtgg gcgtgccgcc gccgccgaag ctcgccgcca
    12901 cgcgcgggta gccggaggcg tcgagcaggc cggtttcgcg gatgccacgc agcttggcgc
    12961 cgatggtgtc gagcgcctcg tcccaggaga tgggcacgaa gtgcgggtcc tcgtggcgcc
    13021 ccttcttcgg gttggtgcgc ttcatcggct gcaggacgcg gttcgggttg taggtcttct
    13081 gcacgaggcc gaaggccttc acgcagaccc ggcccgcggc ggggtgcacg tcttcggcgt
    13141 cgaagttcgg ctcgacggcg gtcgccacgc catcctcgac cttgaccttg agcaggtccg
    13201 gtccggccac gcactgatag cagtaggtgg cgaccttcgt cgtgccctgt gggctgctga
    13261 cggtcatcag gtgtctcctc cggtggtgcg cgggcgaggc tgaggccgcc cgctccccct
    13321 tcttggctta tgggaggaat gctagaactt atgactgacc gaccggttga taaatgtcaa
    13381 agaatgacgt tgacgtgaac ggcaaatatg tgtgtaaagt taacgtgtac gtgaactaga
    13441 gcctgctgcc ctgggcggtg cctttccgat aaactgcagt ccagccgccg acccggtgcc
    13501 cgcacgctcg tgcacgctcc gcgtgcagca aggacggccg caacttgtcc gctgcccctt
    13561 ggctgtcgtc tcgaatccgt tgttttccgc tgtttcctct tccaactgga gtgacccatg
    13621 ttcgtcgaaa acatcatgac ccgggaggtg ttgcacgtcg gtccggaggc ctcgttctcg
    13681 caggtttccg agatcatgcg gctcaagaag gtgcgccacg tgccggtgat cgaccaggat
    13741 cgcaaggtgc tgggcatcat ctcgcatcgc gacgtgcagc gtgcccagcc gtccatgatc
    13801 acgacgctcg acgtcggcga ggtgaagtac ctgctgtcca agatcgcggc ggcggacatc
    13861 atgcacaagt cggtggtgag ctgctcgccg cgcacgcaga tcgaggaggc cgcgcgcatg
    13921 atgcgaccca agaagctggg ctgcctcacc gtggtggacg acgccggccg tctggtaggc
    13981 atcgtcacca gcgtcgacct gctcgacttc ttcctcgaca tcacgggctg ctgggtcgag
    14041 ggcgcgacgc ggatcaccgt gaagctgcag gatcgcgccg gccagctcgc cgcgctgctc
    14101 gcctcggtca atgcgcaggg cggctacatc gtctcggtgg tgtcgccgcg cacgccgcag
    14161 tccgagggcc tgcgcacggc gaccatccgc ttcgaggcga aggatgccgg cgcggtggtg
    14221 cagggcctgc gcgaggcggg ctacgagctg agcgtcgatc agacggcgtg agggtgaggc
    14281 gtcaggcgtg aggggtgaaa accgctcgac ctgacgcctc gtcgcatccg gttgcggtgt
    14341 cgtcggtcga tggccgaggg gcgcagcggg agacttttcg cgcgcgattt cgcttcatct
    14401 tctccgtcgg cacctttcac ctggcctcca aaagccgatg cgcgcgctgg actcccagcg
    14461 cgcgcatcgt ttctggcgcc tgacgcctta ctcccggggc ctcacccttg cagcaacggc
    14521 gggtccgggt cctcgttcca gcccttgggc gggggctgga agcgggagag ccaggcttcg
    14581 agcagggtga cgtgctcgcg ctcggtctcg cagagctcgg cggcgagctt gcggatgtcc
    14641 tcgcgctcgg actgggcgac caggcggtcg tagaaatcga ccccgcggcg ctcggcctcg
    14701 agcgccatcg agatggcgtg gtagggatgc atcatgtagt gcaggccttc ggccgagacc
    14761 gagggcgcct ccgggctctc gggggcttcc caggagtatt cccacggcgc gatgtggggc
    14821 agggtgtgcc cctcgctgat gtcgttcacg ttgtcgacgt gcagcttctc gatctccgcg
    14881 agcttgcgga acagcgcggc gacctcacgg ttgttgtggg tctccatctg gtcggcgagc
    14941 gactcatagc gctcgaccgc ctcgacctcc atcgccagcg cgtgcgccag caggtgctcc
    15001 accgagtgga tgccggtttc ctgcggatcg ggtttgctca taacacgaac tccttctcga
    15061 gatctgccac tgaatcgacg ctcgcctgcc gctcgggctg gaagggcttg cggctgccgc
    15121 gatagagcac gccgacgttg aagccgtcgt cggtcatcag gcggcgcgcg gcgcgcgcgg
    15181 ggtcgtcggt cgggtcgacc gcggcggggt gaaccatgtc cttccagtcg cgctgctcgg
    15241 ggcggaacgt gacgcagggg ctgagcagct gcacgaagga gaagccgggg tggcggatcg
    15301 cctcggtgat gagctgcgcg gtgccgttct ggtcgcctga gaagccgcgg gcgatgaagt
    15361 tcgcgcccgc ggcgagcgcg atcaccagcg ggtggaaggg gttgatgccg gtgccctggg
    15421 gggtgagctt gctcttttcc cagtcgggcg cagtggtcgg cgaggcctgg cccttggtca
    15481 tgccgtagac ctcgttgtcc atgacgatgt aggtcatgtc gacattgcgt cggcaggcat
    15541 gcatgaagtg gttgccgccg atcgagaagc cgtcgccgtc gccgccggag gcgatcacgg
    15601 tgagctcggg gcgcgacacc ttgatgccgg tggcgatcgg cagggcgcgg ccatgcacgc
    15661 cgtggaagcc gaacacgttg gtgtaggcgg gcaggcgcga ggagcagccg atgccggaga
    15721 caagggcgac gcgctcgggc gggatcgaca gctcggccag cgccttggtg atcgagccca
    15781 gcaccgagta gtcgccgcag cccggacacc agacgggctt gacctcggac ttgtagtcgc
    15841 gcgcggaata gctcgggcag gtggatgtgg cttccatgtt cagctccagt cggccagttg
    15901 gcggaagatt tcgttcggac ggatcggcag cgggccgggc cggtggaagg cgcgcacgct
    15961 ccccgggagg tcgtagtgcg cgcgcaggta gcggtggaac tgggcgccgt ggctctgttc
    16021 gacgacgagc acgcgcgcca cgcccgcgag cgcggcggcg agctgctcgg gacgtaccgg
    16081 cgagatcagg cggatcgata ccaggcgcgc gcggccgccg ctggcgcgga agcgctcgag
    16141 cgcctcgcgc accgggccag tggtggagcc ccaggtcagc accgcgatgt cgccgtcacc
    16201 ctcgatgtcc gcccagtgct ggccgtagtc atgcacggcg agcttgcgca ggcgcttgtc
    16261 gagctgtgcg ctgtggtcgg cggcggcgct ggacggggtg ccgtactcgt tgtgctcgag
    16321 gccgtcggcg gtgtactggt agcccttcat gcccggcacc gccatcggcg agacgcccga
    16381 tgcggtgttg gtgtagcggc ggtagcgttc ggaagcctcg ccctcgggca tcaggcggat
    16441 cgcgcgaaag cccgggtcga gcgggggcgc gatcgtcgcc cggctctgcc ccagggactg
    16501 gtcggagagc acgatcgcgg cggtctgcag gctgtcggcg agatggaccg cccactgggt
    16561 ggagaaggcg cagtcggcga gcgagttggg cgccaccacg aggtggggag cgtcgccgtg
    16621 caggccgtag agcgcgatgt tgaggtcgct ctgctcggac ttgaccggga tgccggtgga
    16681 ggggccgccg cgcatcacgt tgaccacggt gatcggggtc tccgaggcga ccgcgaggcc
    16741 gagcgattcg gtcatcaggg cgaggccggg gccggaggtc gcggtcagcg agggcacgcc
    16801 ggcataggag gcgccgatga tctggttgat cgaggcgagc tcgtcctcgg cctgcaccag
    16861 cacgccgccg agcttggcga ggttgggtgc gagccactcg agcacctcgg tgcccggggt
    16921 gatcgggtag gcggcgacga agcggatgcc gccgcgcacc gcgcccaggc cggcagcttc
    16981 gttgccggtg atgctccaca ggcgctcgct ctggccttcg gcagcggcca ggcgggggca
    17041 ggcaggcagc ccggcggcga aggccatgcc ggcgcgcacc gaggcctcgc tggcggtgcg
    17101 cgcggcctct cccttcttgg cgagcgagtc gcgcaccacg ccgagcaccg cgtcctcggg
    17161 cagccctacc agcccggcga cggcgccgag cgcgatcatg ttcggtcgcc cgccctcgat
    17221 ctccttggcc atcttcttga acgggatgtc ggcgcagcgc gcgcccttgg cgccgatctg
    17281 ctcggggaag tcgccgccgt cggggtcgcc gagcaccagg ccgtcggagg tcatcgggat
    17341 ctcggcggag aagcggccga cgttctgcca gtcgatcgcg accagcacgt cgaagtggtc
    17401 gtcgtgcgac tgcaccggcg aggttgacag acgcatcatc gcggcagcct cgccgccgcg
    17461 gatctgtgcg cccgacgagc gggtcatgta ggcataccag ccggcgcggc cggcggcgtc
    17521 gagcagcatg ttgcctgcgg tcatcacccc cgcgccgccg ctgccggcga atgttatcga
    17581 taccgatcgg gctgtcatcc tcgttctcca atgttcgacc ttcgctggcg ggtgccggcg
    17641 cggtcctgtt cagggcccct gcgcgcgtcc cctcgggtga agcgggcacg gcgccaaccg
    17701 gaggctggat ggttcgctgc gccatcgcct ggcgctcacc cccgatgcga caaagtttac
    17761 gttgacgcaa acgtcaatct gttgactttg gtcaactgcc ctcctgccgg ggtgatttaa
    17821 ctttgcatcc aacgcggcga cagggaggca gtggatcccg ttgccgaccg agccggatta
    17881 agttgacgcg aacgtaaacg gaaggagtgg gtagatgagc accaaaccgt atcgctggat
    17941 gatggtggag ccggggcggc cgatggtccg caccgagttc gagatcggcg agctggccgc
    18001 cgaccaggta gtggtcgagg tcgccggctg tggcgtctgc cacaccgatc tcggctacta
    18061 ctacgacggc gtgcgcacca accaggcgtt gccgctcgcg ctcggccacg agatcagcgg
    18121 ccgggtggtg ggtgcgggca gcgcggcggg gcagtgggtc ggccgcgcgg tggtcgtgcc
    18181 ggcggtgatg ccctgcggca cctgcgagct ctgcacctcg ggacacggca cgatctgccg
    18241 cgcccaggtc atgccgggca acgacatcca gggcggcttc gcctcccaca tcgtggtgcc
    18301 ggcgcgcggc ctgtgcgcgg tcgatgagca gcgcctcgcc gccgccggcc tgcagctcgc
    18361 cgacgtctcg gtggtggccg acgcggtcac cacgccctac caggcggtga cgcaggccgg
    18421 cgtcgagccc ggcgacgtgg cgatcgtgat cggcgtcggc ggcgtgggtg gctacgcggt
    18481 gcagatcgcc aacgccttcg gcgcgagcgt ggtggcgatc gacgtcgatc cggccaagct
    18541 ggagctcatg tcgaagtacg gcgcggcgct gacgctcaat gcgcgagagg tcaccgggcg
    18601 cgacctcaag aaggcgatcg aggcccacgc caaggccaac ggcctgcgca ccacgcgctg
    18661 gaagatcttc gagtgctcgg gcagcggcgc cggccagacc aacgcctaca gcctgatcaa
    18721 ccacggcgcc acgctcgcgg tggtgggttt cacgatggac aaggtcgagg tccgcctctc
    18781 caacctgatg gccttccacg cccgcgcgct cggcaactgg ggctgcctgc ccgagtacta
    18841 ccccgccgcg ctcgacctgg tgctcgacgg ccgcatcaac ctcgccaact tcgtcgagcg
    18901 tcacccgctg gcgcagatca acgaggtctt cgaggcggcc catgcccaca agctgacccg
    18961 ccgcgcgatc ctgaccccct gatcccgcac ccccttccat accgacaaga gagcagacag
    19021 aggagccaca gaagatgaaa gagacgacgc aacgcgtgat cgaccagacc gcgcccaagc
    19081 acctggtcga tcacaacctg gtacccgaga cggtggtgcc cggcgtgatc tacgagaagc
    19141 gcccggcgcg caacctgcag ggcgaggtcg tccccggcct gtacaacgcc tggatctggc
    19201 tggacaaccc gaagcagtac aactcctaca ccaccgacat ggtgaagggg ctgatcctcg
    19261 ccttccgcgc cgcgtcctgc gcccgtgacg tcgccacggt cgtgttcacc gcggtcggcg
    19321 acaaggcctt ctgcaccggc ggcaacacca aggagtacgc cgagtactac gccggcaacc
    19381 cgcaggaata ccgccagtac atgcggctgt tcaacgacat ggtgtcggcg atcctggggt
    19441 gcgacaagcc ggtggtgtgc cgcgtcaatg gcatgcgcat cggcggcggc caggagatcg
    19501 gcatggcggc ggacttcacc gtcgctcagg acctcgccaa cttcggccag gccggtccca
    19561 agcacggttc ggccgcgatc ggcggggcca ccgacttcct gccggtgatg atcggctgcg
    19621 agcaggccat ggtctccggc acgctgtgcg agcccttctc ggcgcacaag gcctaccgcc
    19681 tcggcatctc ctcgcagatc gtccccgcgc tcaaggtcga cggcaagttc gtcgccaacc
    19741 cgctggtgat caccgaccgc tacctcgacg agttcggtcg catcatccac ggcgagttca
    19801 agaccggcga cgagctggcc gccggcaagg agctgctcaa gcgcggcgag atcgacctgt
    19861 cgctgctcga cgaggccgtc gagaagctgt gcgccaagct catctccacc ttccccgagt
    19921 gcctgaccaa gagcttcgag gaactgcgca agcccaagct cgacgcctgg aaccgcaaca
    19981 aggaaaacag ccgcgcctgg ctcgcgctca acatgatgaa cgaggcccgc accggcttcc
    20041 gtgccttcaa cgagggcaac aaggacacca gccgcgagat cgagttcacc gacctgcgcc
    20101 aggcgctcgc cgtcggcacg ccctggacgc ccgagctgat cgaaagcctg atgccggggg
    20161 cgaagtgatg ggcgaggcga tcaacccgct caaggcctgg ctcgagcgcg acggcggcct
    20221 gctccgcctg cgcctcgcgc ggcccaaggc gaacatcgtc gatgccgcga tgatcggcgc
    20281 gctgcaggag gcgctcggcg cccacctcgg ttcgccggcg ctgcgcgcgg tgctgctcga
    20341 cgccgagggg ccgcacttca gcttcggcgc cagcgtcgac gagcacatgc ccgagcagtg
    20401 cgcgcagatg ctcaagaccc tgcacgcgct ggtgcggcag atgctcgaca gcccggtgac
    20461 gatcctggtc gcgatccgcg gccagtgcct cggcggcggc ctggaggtgg cggcggcggg
    20521 caacctgctc ttcgtcgcgc cggatgcccg cctcggccag ccggagatcc gcctgggggt
    20581 gttcgccccc gcggcctcct gcctgctgcc gccgcgcgtc gggcagtcgc gtgccgagga
    20641 gctgctgttc tcgggacgca gcatcgacgg cgccgaggcg ttccgcatcg gcctggccga
    20701 cgtgctcgcc gacgaccccg aggcggccgc gctgaagtgg tacgacgaac atcttgctgc
    20761 gtcgagcgcc agctcgctgc gtttcgcggt gcgtgccgcg cgctgcgacc acgtgccggc
    20821 gatcaagcaa aaactggaaa ccgtggaggc catgtatctc gaggagctga tggccagcca
    20881 cgatgcggtg gaaggtctac gggcctttct tgagaagcgt tctgcaaact gggagaaccg
    20941 ttgaccatga gtacggcaga catcatcgcg cgctgtgaag cgctctacga agacctcgat
    21001 ttcaccgccg caaggaagtg gaaggaggcc gacccctcgc gcaaggtaat cgcctacatg
    21061 ccggtgtacg tgccgcgcga gatcatccac gccgcgggca tgctcccgct cggcatcatg
    21121 ggcggaggcg acggcctgga ggtcatccac ggcgacgcct actaccagag ctacatctgt
    21181 cgcatcccac gctcgaccat cgagctgggt ctgtccaagc gcatggattt cgtggacggc
    21241 atgctgttcc ccagcatctg cgacgtgatc cgcaacctgt ccggcatgtg gaagctgctg
    21301 ttcccgggca agtacgtgcg ctacttcgac gtgccgcaga actacaagga cgacgtcggc
    21361 ggcagctact acaccaacga gctgaacgag ctgcgcgaag gcctcgagca cctgtccggg
    21421 cgcaagatca ccgacgatgc gctgcgcgcc tcgatcgagg tctacaacga gaaccgcaag
    21481 ctggtgcagg ccgtgtatgg catgcgttcc cgcgagccct ggaaggtgcc ctcgtccgag
    21541 gtctacctgc tgatgcgcgc cggcctggtg gtgcccgtcg aagagcacaa ccagatcctg
    21601 cgcgactacc tggccgcggc cgagaaggtc caggcctcca agcgcgacaa ctgccgcgtg
    21661 gtcatcaacg gctcgttctg cgagcagccg ccgctcaacc tgatcaagtc gatcgagctc
    21721 gccggctgct acatcgtcga tgacgattac atcatcgtgc atcgctggct gcgcaacccg
    21781 gtctcgacca gcggcgaccc gatgcagaac ctgtcgctcg ccttcctgca cgagtcgatc
    21841 gccaccgcag ccaagtacga cgacaaggaa gaggacaagg gcaagtacct gctcgagcag
    21901 gtgcgcagca acgccgccga aggcgtcatc tttgccgcgc ccagcttctg cgaccccgcg
    21961 ctgctcgagc gcccgatgct ggccgaccgc tgctcggagc acaacgtccc ctacatctcg
    22021 ttcaagtacg cggagaactc gggccagatg cagccgatcc gcgaacaggc cggcaccttc
    22081 gccgactcca tcaaactctg gagctaatca tgagcgcagc cacctccccc gaagtcatca
    22141 aagaaccctc gatggtgaag cagaaggaga tgatcgccgg caactacgat cgtctcacca
    22201 gcaccaagga gtcgggcgag aaggtcgtgt cgaccttcgt cccgggcaac ctgaacgagc
    22261 tgatcatgtg cttcgacatg gtcaacaacc tgcccgagac caacgccatc cagaacggca
    22321 tgcgcaaggt ttccggcggc atgatcatgg acgccgagaa ggccggccac tccgaggacg
    22381 tgtgcaccta cgtcaaggcc gacatcggca tgatgggccg cggcaacatc gcccccaacg
    22441 gcaagccgat gcccgccccg gacatgctgc tgctgtccta caccggctgc ttcaccttca
    22501 tgaagtggtt cgagctgctg cgccacgagt acaagtgccc gaccgtgatg ctgcagatcc
    22561 cgtaccaggg cgacggcaag atcaccaaga acatgcgtga cttcgtcgtc aagcagctca
    22621 aggaagaagt catcccgatg ttcgagaagg tctcgggcgt caagttcgac atcgaccgcc
    22681 tgcgcgaata cctgaagaac tcggcgaagg ccgaggacaa cctggtgtgg gtgctcgaga
    22741 gcgcgaagaa ccgtccctcg ccgatcgatg cctacttcgg cggcgtgtat tacatcggcc
    22801 cgatgttcac cgccttccgc ggcaccgccg acgcggtcga gtactacgac ctggtgcgca
    22861 aggagatcga gcagcgcatc cgcgagggca agggcccgat cacgcccgaa ggcgacatga
    22921 aggaagagaa gtaccgcctg gtcgtcgagg gtccgccgaa ctggaccagc ttccgcgagt
    22981 tctggaagct gttctacgac gagggcgcgg tggtggtggc gagctcctac accaaggtgg
    23041 gcggcctcta cgaccagggc ttccgtcacg acccgaacga tccgctcggc acgctggccg
    23101 actactgcct gggttgctac accaacaaca acctgccgca gcgcgtcgaa ctgctcgaga
    23161 agtacatgaa cgactaccag gcggacggct tgctgatcaa ctcgatcaag agctgcaaca
    23221 gcttctcggc gggtcagctg ctgatgatgc gcgagatcga gaagcggacc ggcaagccgg
    23281 cggcgttcat cgagaccgac ctcgtcgatc cgcgctactt ctcccatgca aacgtcaaga
    23341 accgtctgga gagctatttc cagatggtcg atcagaaacg cagcggcgct tcgctggcag
    23401 ccgcgtaagg agcgaaccat ggaatgtttc gtcggaattg atctggggtc caccacgacc
    23461 aaggcggtcg tcatggacga caaggggcag gtgctcggcc gcggcatcac caactcgcgc
    23521 tcgaactacg ataccgccgc acgcgtctcc aagctcgagg ccttcatcga tgcacgcctg
    23581 agcctgatcc gtcgcgaact cgagaaggtg ccggccgtgg ccgacagggt cgacgagatc
    23641 ctgtccgggc tgacgcgcaa cttccgccgc gagcagttcg tcgagcagct cggcgacctc
    23701 gagcagacct gcgtcgccaa cgtcgaaggc ccgcgcttcg ccggcaagga gaaggcgatc
    23761 atcggcgcgc tgaccgaagt cttccgccgc ctgcgcgagg aagaggccga caagctgttc
    23821 gcgcccaccg cgcagcgcaa gtcggacttc ttccgcgacc tcgccggttc gcgcttcatg
    23881 cagatcggcg aagaagtggc gcgtgatgcc ggcgtgccct tcgaccacct gctgcacatg
    23941 tacgacaagt cgatcatcga ggtcgagaac cgtccgccct cggccgacat gaaccgcaag
    24001 ttccgcaccg cgatggagcg ggtgcgcggc gagctctccg gtgccgacct cgacaccgcc
    24061 gcgctcggcg cgccgatcga cgccgcgctc gatgtcgaca tggtcgagcg ctacgtcgtg
    24121 ggcaccggct acggccgcgt ccgcctgcct ttcccgaagg agcacatccg ctccgagatc
    24181 ctctgccacg gcctgggcgc ccacctgatg tatccgaaga cgcgtacggt gctcgacatc
    24241 ggcggccagg acaccaaggg catccagatc gacgagaagg gcatcgtggt caacttccag
    24301 atgaacgacc gctgtgccgc cggcaccggc cgctacctgg gctatgtcgc cgacgagatg
    24361 aacatgggcc tgcatgagct cggcccgctc gcgatgaagg cgaccaagtc gatccgcatc
    24421 aactcgacct gcaccgtgtt cgccggtgcc gagctgcgcg accgcctggc gctgggcgac
    24481 aagcgcgagg acatcctcgc cggcctgcac cgcgccatca tgctgcgcgc gatgtcgatc
    24541 atctcgcgct cgggcggcat caccgacgag ttcaccttca ccggcggcgt ggccaagaac
    24601 gaggccgcgg tcaaggagtt gcgccagctc gtcaaggaaa actacgggga ggtgaagatc
    24661 aacatcgacc cggattcgat ctataccggt gcgcttgggg cttccgaatt cgcccgccgc
    24721 gccgtcgtgg aggcttgaac atgaccatca ccgcaggcat cgacatcggc accggcgccg
    24781 tcaagaccgt cctcttccgc gtcgagggcg acaagaccga gtggctggcc aagcgcaacg
    24841 accgcatccg tcagcgcgac cccttcaagc tcgccgagga ggcctaccac gcgctcctcg
    24901 aggaagtggg cctgaaggcc tccgacgtgg attacgtcgc cactaccggt gaaggcgaga
    24961 gcctccactt ccacaccggc cacttctact ccatgaccac ccacgcgcgc ggcgcggtct
    25021 tcctcaaccc cgaggcgcgt gcggtgctcg acatcggcgc gctgcacggg cgggcgatcc
    25081 gcaacgacga gcgcggcaag gtcgagacct acaagatgac cagccagtgc gcctcgggct
    25141 cgggacagtt cctcgagaac atcgcgcgct acctcggcat cgcccaggac gagatcggct
    25201 cgctgtcgaa ccaggccgac aaccccgagg tggtgtcgag catctgcgcg gtgctggccg
    25261 agaccgacgt catcaacatg gtgtcgcgcg gcatcacggc gcccaacatc ctgaagggca
    25321 tccacatctc gatggccggc cgcctggcca agctgctgaa gtcgatcggc gcacgtgagg
    25381 gcgtggtgct ctgcaccggc ggcctggcgc tcgacgaggg cctgctcaac accctcaacg
    25441 agtcgatcaa ggaacagaag atggcggtga cggccttcaa ccaccccgac tcgccgtttg
    25501 ccggcgccat cggcgcggcc ctgtggggcg ccttccgcca cgagaaactc gcgcgcctgg
    25561 gcgggcagca gctcgccgcc gcggcctgaa accagcgtac aggaggaagc catcatggcc
    25621 ctgctcatca atgacgactg caccgcgtgc gatgcctgtg tcgaggagtg cccgaacgag
    25681 gcgatcaccg ccggcaatcc gatttacgtg atcgatccga acaagtgctc cgagtgcgtg
    25741 ggcgcccatg acgagccgca gtgcgtgctc gtctgcccgg ccgactgcat caagcctcac
    25801 ccggactacc gtgaatcgca ggacgaactg caggccaagt acgacagcct gcactgatcc
    25861 atcggtgggg acgccggcac gggtccccac cccagtcatc tcagggagac gcaatgactg
    25921 cgaataccga aatcaagctg cggccgctgg ccgcaggcga cctggcggcg gtcacccgcc
    25981 tcgacgcgac caacggcggc gagagccgcg ccggcttctt cgagcgccgc ctccaggccg
    26041 agcagcagag ccccgcgggc ttcttctcct gcgtggccga gcgcggcggc gaagtcgccg
    26101 gtttcctgct ggggcacctg ctcgacggcg agttcggcgg cctggagcgc gtcgcggtgc
    26161 tcgacgccgt ggcgatcgac cccgccgccc agcgccaggg cctcgcccgc aagctggtcg
    26221 gcgagttcga ccgcaacgcg cgcgaacgcg gcgccagcga gatgcgcacc caggcgcagt
    26281 gggatcgtcc cggtctggtc gagttcttct ccgcggccgg cttccgcctg tcgccgcggc
    26341 tggtgctcga gcgcccgacc gaatacgtga acttctgagc tcacgtccgg aaacgacaac
    26401 ctggagatca gcgatgacca cgcgtccgca tcccaccacc aagcaactgc tggaccagtt
    26461 caacaccgag cccgactaca gcgacgccag ccaggacgac gccgaggccc tgtcgcgcga
    26521 ccgcatcccg gtgcgctcgc tcaccgcggc cgacttcgac gccgtcgtcc gcatcgaccg
    26581 ccgcagcacc ggccatgacc gcagcgccta ctaccggcgc aagttcgacg aggcgctcgg
    26641 cgagtccggc gtccgcgtct cggtcgtcgc cgagcaggac ggcatggtcg ccggcttcct
    26701 gatggcgcgg gtcgacttcg gcgagttcgg ccgcgccgcc accgccgcgg tgatcgacac
    26761 catcggcgtc gacgcggcgg ccagcggcaa gcacgtcggc cgcgcgctgg tgtcgcagct
    26821 gctcgccaac ctgacctcgc tgcacgtcga gtcggtgcgc accgaggtcg agtggaaccg
    26881 cttcgacctg ctgcgcttcc tcgaccgctg cggcttccgt cccggccaac agctctcgct
    26941 gtcgcgcccg ctcgtctgag cgtttgcgac gaaccggccc ggggcccgcg tcagcgggct
    27001 ccgggcgcat gcacatccag aggggaagcg gctcatgggc tttacgggac aactggcggg
    27061 gaaggtcgcg atcgtcaccg gcggcgcgcg cgggatcggg cgcacgatca ccgacgcgct
    27121 ggtcgcgcgc ggcgcgcagg tgcatgtctt cgacatgacc gacagcaacg agtcggcggg
    27181 cgtgctgcac cgggtgaacg tggccgacgc gcagtctgtg gccgacgcgg tggcgcagct
    27241 gcccgagccg gcgacgctgc tggtcaacaa cgccggcatc acgcgcgacc gcagcctgct
    27301 caagatgagc gacgacgaat ggcgctcggt gctcgacgtc aacctgagcg gtgcgttcca
    27361 catggtgcgc gcgtgtgcgc cgggcatgat cgcggccggc agcggccgga tcgtcaacat
    27421 cacctcgatc aacgggctgc gcggcaagtt cggccaggcc aactacaccg cggcgaaggc
    27481 gggcatgatc ggcctcacca agaccgccgc gcgcgaactc ggtcccaagg gcatcaccgt
    27541 caacgcggtc gcgcccggca tggtcatgac cgagatggcg cgcgcgctgc cggccgaggt
    27601 gctcgagcgc gcgctgcagg agtcggtgat gcgcgagctc gccacccctg aagacatcgc
    27661 cgcggcggtc gtgttcctgc tgtccgacat ggcgcgcatg atcaccggcg aggtgatccg
    27721 ggtggacgcc gggcagtacg tatgaagcat cgcaaagcgg cctgggaagc cgctttgcgc
    27781 gtagcatgca tcacgcccgc ggggcgcgga atcgtctacc attgagacgc ttttcgtgga
    27841 accgcaggta tcgggtttca tcgggtggca agaagggcgg cccgtcatgg tcaggctggt
    27901 cgcctaatcc ataacgaccg gaggagatac catgaaactg aagaagaccc tgttcgtcgc
    27961 gctcggtctc gcctttgcgg cgggcgccgc ccatgcccag ctcaaggtgg gcatcaccgt
    28021 ctcggccacc ggcccggctg cctcgctcgg catccccgag cgcaacaccg tcgagctgat
    28081 gcccaaggag atcggcgggc agaaagtcac ctacatcgtc ctcgacgacg cctcggacac
    28141 caccagcgcg gtcaagaaca tccgcaagct ggtctccgag gacaaggtcg acgtcgtgct
    28201 cggctcgacc acctcgccca actcgctcgg catgatcgac gtcgccgccg agtcgcagac
    28261 cccgatgatc gcctgggccg cctccagccg catcgtcgag ccggtggacg acaagcgtcg
    28321 ctgggtgttc aagacgccgc agaacgactc ccacatgtcg accgcgatcg tctcccacat
    28381 gacgagcaac aacgtcaaga acgtggcctt catcggcttc gccgacgcct atggcgaggg
    28441 ctggtacgag cagttcaagt cggtcgccga ggcgcgcggg atcaagatcg tcgccaacga
    28501 gcgcttcacc cgcaccgaca cctccgtcac cggccaggtg ctgaagatga tggcggccaa
    28561 gccggacgcc atgttcatcg cgggctcggg cacgccggcg gcgctgccgc agaagacgct
    28621 caaggagcgc ggctggtcgg gcaaggtcta ccagacgcac ggcgtcgcga acaacgactt
    28681 cctgcgcgtc tgcggcgccg actgcgaggg cacgctgctg cccgccggcc cggtgctggt
    28741 cgccgagcag ctgcccgacg acaacccggt caaggcgagc gcgatgacct acatcaaggc
    28801 ctacgaggcg gcgcacggca agggcagcgt gtcgaccttc ggcgcgcacg cctgggattc
    28861 gggcgtgatg ctgcaggccg ccgttcccga ggcgctcaag aaggcccagc ccggcactgc
    28921 cgagttccgc gccgcgctgc gtgacgcgct cgagaacatg aaggaggtcc ccgcggccca
    28981 cggcgtgttc acgatgggtc cgaacgacca cctcggcctt gaccagcgcg cgcgcgtgat
    29041 ggtgcagatc cagaagggcg cctggaagct cgtccagtaa gcgacgctcc cgtgcggtcg
    29101 ccgtgccgcg ggcgcggcga ccgtgccttt cccatcagtc ggtccactcg atcgcgcttc
    29161 ggttcatgac cggggcgcgc ggaggctcgc gcccatggat ttccagattg cactgatcct
    29221 cggccaggac ggcatcacca acggcgccat ctatgcgctg ctcgcgctcg cgctggtgct
    29281 cgtgttcgcc gtcacccggg tgatcttcat tccgcaggga gagttcgtcg cctatggcgc
    29341 gctcaccctc gcgatgatcg gtaacaacgt cttccccgcc acggcctggc tgctgctcgg
    29401 cgccggcatc gccgtcgccg ccctcgatgg gctcggggcg ctgcgggccg ggcaggcgcg
    29461 caagctgcct cgcgtgctcg cggtcaatgt cggctacccg ctcgcggtga tcgcactcct
    29521 gcgcctgttg ccgctggccg agctcggcct cgcggtgcag atcctgctcg ccatgctgat
    29581 cgtggtgccg ctcgggccga tgatgtaccg catcgtctat cagccgatcg ccgaggccac
    29641 ggtgctggtg ctgttgatcg tctcggtcgc ctcccacgtc gccatggtgg gcctggggct
    29701 gctgttcttc ggcgcggagg gataccgcac gccgccgctc tcggatgcac gcttcgacct
    29761 cggttcgctg tcgatcagcg gacagacgat ctgggtggtc gccgcctcga tcgtgctgat
    29821 cgtcgcgctc gcgctgttct tcggccgcac gatctacggc aaggccctgc gcgccaccgc
    29881 gatcaaccgc aacggcgccc gcctgatggg gatcccgccc gcgctcgccg gcaagctcac
    29941 cttcctgctc gccgcgctga tcggcgtgct gtcgggcgtg ctgatctcgc cgatcaccac
    30001 gatctactac gacagcggct tcctgatcgg cctcaagggc ttcgtcgccg cgatcatcgg
    30061 cgggctggcg agctatccgc tcgccgcctt cggcgcggtg ctggtcggcc tgctcgaatc
    30121 cttcagctcg ttctgggcca gtgcctacaa ggaggtcctg gtgttcacac tgatcatccc
    30181 ggtgctggtg tggcgctccc tgaccagcca ccacgtggag gaagaggaat gaa
//
LOCUS       DAOTIN010000033        29868 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_1749_length_29868_cov_9.319928, whole genome shotgun sequence.
ACCESSION   DAOTIN010000033 DAOTIN010000000
VERSION     DAOTIN010000033.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 29868)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 29868)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29868
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1749_length_29868_cov_9.319928"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..701)
                     /locus_tag="P5537_07110"
     CDS             complement(<1..701)
                     /locus_tag="P5537_07110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV77848.1"
                     /translation="MDAGLFTSMLFATVVAGTPLIIVALGLLVNEKAGVLNLGAEGMM
                     AMGAVAAFAVTHESGNPWLGVAAGVGAGMAMAAIFGVLALTLMANQVASGLALAIFGV
                     GLAAFVGKPYEAVALQAVPPIRIPFIADLPLIGEALYNQQALVYFSWALFWGLLWFLH
                     RSRAGLVLRAVGEAPSSAHAIGYPVIRIRYLAVLFGGAMAGVGGAFLSVFYTPMWAEG
                     MVAGRGWIALALVVFA"
     gene            complement(712..1776)
                     /locus_tag="P5537_07115"
     CDS             complement(712..1776)
                     /locus_tag="P5537_07115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV77849.1"
                     /translation="MLELEARAEPSRLMSWASPLLAVALMLAGGLAVFAALGKDPVEG
                     FRVFFLNPVKDLYALSELLLKATPLMLCAIGLAIGFRANVWNIGAEGQFMLGAVAATG
                     VALYFGDSESALVLPAMVLAGAAGGAAWAAIPALLRTRFNANEILVSLMLVYVAQLFV
                     SWLVFGPWKDPDGFNFPQTRMFAEAATLPMVIEGTRLHFGFAIALAALVAGYAFMNRS
                     HAGFRMRVAGEAVDAARYAGFSATRMIWVGLLLGGAAAGLAGMGEVAGPMGQLTDKVA
                     SGYGFAAIIVAFVGRLNAFGILLASLLMALLYIGGEQAQQYLNLPNSISMVFQGMLLF
                     FLLGADVFIHYRLRLRRRGA"
     gene            complement(1769..3367)
                     /locus_tag="P5537_07120"
     CDS             complement(1769..3367)
                     /locus_tag="P5537_07120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV77850.1"
                     /translation="MPILPPLTPPQPSAAAPARLVLQGIGKVYPTVVANDDIGLTVRA
                     GEIRAILGENGAGKSTLMKIIYGVTRPSSGRMFWEGEEVQVESPAHARSLGIGMVFQH
                     FSLFETLTVVENVALALPGKPALDALAQRIVEVSARYGLPVDPRRHIHALSVGERQRV
                     EIVRCLLQDPRLLIMDEPTSVLTPQAVRKLFETLRRLADEGCSILYISHKLDEIRELC
                     HTATVLRGGRVTGECIPAQETPASMARLMIGKELPRCEHDAPQAGGEVRLRLAGLSHA
                     SDDPFGTDLRDLHLDVHAGEIVGIAGVSGNGQQELLRVISGEEPLAERFPVQICGVEA
                     GRLSPGRRRRLGMAFVPEERLGRGAVPTMSLADNALLTAAHNQGLVTAGFLRFERARA
                     FARRCIDDFNVKCGGPAAAAKSLSGGNLQKFIVGREILQAPRLLVCAQPTWGVDVGAA
                     AFIRQQIIDLRNRGCAVLVISEELDELFEICDRIAVIAKGRLSPVRAAGDTSIEDIGV
                     WMSGLWPGAGDTADAPLAMETPHA"
     gene            complement(3426..4220)
                     /locus_tag="P5537_07125"
     CDS             complement(3426..4220)
                     /locus_tag="P5537_07125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HRV77851.1"
                     /translation="MSTPLPTPTCPACGSIDCRRSRWRSHEEHKSHPGLHPWRCRSCD
                     KRFIGPDDAAGPGRKWPLVVGILSLLSLLAIGIATVSMLDRDDPLPGGEPESAAADAS
                     LPTDALDAQFRAARAALLDTARGREVSSDAVNRLRQAAEGGHTGAMVLLGKLYRSGIG
                     MPQNYALAARWLGDAANAGDPEGMVEFGRLHRSGIGVEQDAVQAYVWFNRAAALLNME
                     GVQERDSIAVKLGADELHRAQALSLEAAEAEAAKGEAAAGQEDGSR"
     gene            complement(4234..4473)
                     /locus_tag="P5537_07130"
     CDS             complement(4234..4473)
                     /locus_tag="P5537_07130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77852.1"
                     /translation="MPTCPRCDGTDCRESPWKSADERLAHPGERAWRCMSCVHRFHAP
                     VSRGLLRDNPIVAAVGGGTLLLTIAVIVILWIWKS"
     gene            complement(4655..7528)
                     /locus_tag="P5537_07135"
     CDS             complement(4655..7528)
                     /locus_tag="P5537_07135"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HRV77853.1"
                     /translation="MSETTSASTQNTAKASAANLPMQEISGEVLVEKYAKGDEQTVAE
                     VRRRVARALAAIESEDKRAHWEAKFLEAQEKGFVPAGRINSAAGTTLAATLINCFVQP
                     VGDSVTEAVDGRPGIYTALAQAAETMRRGGGVGYDFSSIRPKGALVKGTASNASGPVS
                     YMRVFDRSCETVESAGARRGAQMGVLRCDHPDIEEFIHAKDEGDLTNFNISVGVTDPF
                     MQAVEADGDVELVHKAEPTDEVKSAGAYQRDDGLWVYRKVRARELWDQVMRSTYDHAE
                     PGILFLDRMNADNNLYYCETIEATNPCAEQPLPPYGCCCLGSINLTLFVRNPFGDKAE
                     FDYAAFGKVIDTSIRMLDNVLEVTHWPLEQQHAEAQSKRRVGLGFTGLGDALIMLGQR
                     YDTPEARDEARRISEYMRNRAYLASTELARERGAFPLFNADLYLSGGNFASRLPADVK
                     DKIRKHGIRNSHLLSIAPTGTISLAFADNASNGIEPPFSYTYTRRKRMADGTFKEYAV
                     EDYAWRLYKHLGGNVEALPQSFVTALEISAQAHKDMVAAVAPYVDTSISKTVNVPEDY
                     PYAEFEDLYLTAWKAGLKGLATYRPNNVLGSVLSVTPTAEQKQPHDVEIADANKRLSI
                     KNLPAPVLSSLRWPGRPDLPDGNLAWTYMLNTPTGGFALFVGQVGNNGGSFPFEVWVN
                     GADQPRGLGAVAKTLSMDMRANDRGWLKLKLDTLARTVGERSFEMPFPPHGEKKLVPG
                     VVSAFAQVVNYRCEKLGVFDKEDESNGVLDTLFSLEEPKTGTDGTLSWTVDIYNPATG
                     EDFVLGLKEITLPDGVTRPYSVWLSGNYPRALDGLTRILSLDMRVMDPAWIGMKLRKL
                     LDYPEPLGDFMAFVPGTRRQQNWPSTVAYLAQLIIHRYAMLGVLDERGYPTREMGILE
                     SPRDDNEPKLMQGALCNECGNHTVIRKDGCDFCTACGAVGTCG"
     gene            complement(7746..8594)
                     /locus_tag="P5537_07140"
     CDS             complement(7746..8594)
                     /locus_tag="P5537_07140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDOD domain-containing protein"
                     /protein_id="HRV77854.1"
                     /translation="MHSAQELVSQIEALTSLPDVYMRVREQLESPAGSVATVARLVAA
                     DPALSARLLHLVNSPLFGQRGRVEDIVRAVALLGLQQVHDLVLAMSLQGIFAGVRPAH
                     LDMRRFWRNSLLTGLAARAAGVAAGLTAGERLFLIGVLADTGHLVMYQTVPEHAAAAR
                     LAAQAGEEALDAAERRIVGCDFAELGAALLDRWQLPERFSTAVGAQMLPRLGGAYAAE
                     AATVNLARCIAEADELDLPSSAAATRVAAETWDLLGLEPERLAGLREGAEIDFAAYLS
                     LFFPRR"
     gene            complement(8625..9638)
                     /locus_tag="P5537_07145"
     CDS             complement(8625..9638)
                     /locus_tag="P5537_07145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011765151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HRV77855.1"
                     /translation="MHLHSAHEHHTPDDDHGGPEHGHGYEHEQAHRHHGGHHHHAHDH
                     SASRFLPLALVLTLGFALVEAIAGWWSGSLALLGDAGHMLTDAASLGLAALAARIALR
                     PTSVRHSWGLRRVEALAALANGLFMLVIVGGLVWHAVERLLEPRAVAGEAVILVALGG
                     LVLNLAVAWLLTRGEGDLNTRGALLHVIGDLLGSVAALASGIVILYTGWMPIDPLLTM
                     MICGLILYSTLSLLRQVVHTLLEGVPDSLSLPEVGRAMAGVEGVRSVHDLHIWSLDSR
                     RTALSAHVVLADAARWPAVLEAERALLHGRFGIEHATLQPELPPAQPLVFTPRMRRTH
                     DAG"
     gene            complement(9750..11066)
                     /locus_tag="P5537_07150"
     CDS             complement(9750..11066)
                     /locus_tag="P5537_07150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HRV77856.1"
                     /translation="MLNRKLKTTLQEQQAELAARQAVIDAIDRTTARIEFAPDGTVLF
                     ANELFLATMKYRSEDVLGKNHRMFCEEGYANSSDYLAHWQRLRRGEPVSGRFERRDAS
                     GEPVWLEATYNPVFGPDGRVLRVVKLATDITAQMREGAERRAMLAAIERSMAMIEFDL
                     DGKVLAANDNFLATMGYARGEVLGRHHRLFCAAEDAEAPDYARFWERLRHGEYFSGRF
                     RRVARNGRTVWLEASYNPVFDEAGRPCKFIKLASDISSRVEALEEEIANAAAALERAR
                     DNAHLAERGTDVIARATTQMVAISDSAEDAVHTFGQLGDETGRITTIVNTIREIADQT
                     NLLALNAAIEAARAGEHGRGFAVVADEVRKLAERTSRATTEISAMISTVQDATHLAIS
                     RVHGMHETATASIDLAREAGEVIDGIHNGATAVVNVVERFSGLLQR"
     gene            11238..12140
                     /locus_tag="P5537_07155"
     CDS             11238..12140
                     /locus_tag="P5537_07155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004327153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HRV77857.1"
                     /translation="MKKTTGQRKRGIRLLSWNIQWGRGADGRVDLERTRDTIRAAGPL
                     DVICLQEVASNFPGLAGGAREDEPAFFAAAFADFEPVFGAGMDVPDGEGGRARFGNLL
                     LSRLPVGQVFRHLLPSPADPAWPAMQRVCVEAVVEAPWGPLRVMSTHLEYYSARQRRA
                     QVEALRALQAEAADLARLPAAGKESNPAFAARPRPAAAVLCGDFNCEPGSAEHLALQR
                     PLPASGLAPDAHRPHWVDAWPIAHGARAHAPSVGLHGAEWPDRAYCCDFFFVTSDLAP
                     RVHALEVLADTAASDHQPVVIELA"
     gene            complement(12175..12966)
                     /locus_tag="P5537_07160"
     CDS             complement(12175..12966)
                     /locus_tag="P5537_07160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HRV77858.1"
                     /translation="MTRTLQLDGRRAAFDESGLATAPAILLIHGAGHDRGVWQAVTAG
                     LAAAGRRVIVPDLPGHGDSAGEAAGAVDTMAAWVLAFADAAGLERFELAGHSMGSLIA
                     LAAAAAAPARIIRLHLLGSLAPMPVAPFLLDAARSDPAQAHALINKFSFAPAEVLGEE
                     RRRALEAGNRARMERNGSETLAHDLAACNAWQDGLAAATRRDCPTLLLCGALDRMTPV
                     KAIGPLHEALRAGGGEVRRVELPGCGHAMQEEDPAAVVRALLWSD"
     gene            complement(13124..13339)
                     /locus_tag="P5537_07165"
     CDS             complement(13124..13339)
                     /locus_tag="P5537_07165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcH family protein"
                     /protein_id="HRV77859.1"
                     /translation="MSGESFDDVTSLRQRLEELRLEHRDLDDAIARLADNPVEDELML
                     RRLKKRKLALKDRIVAIEHMLDPDEYA"
     gene            13540..14094
                     /gene="greB"
                     /locus_tag="P5537_07170"
     CDS             13540..14094
                     /gene="greB"
                     /locus_tag="P5537_07170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0070063 - RNA polymerase binding [Evidence
                     IEA];
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreB"
                     /protein_id="HRV77860.1"
                     /translation="MNKAFVKESDGNDEDEELAPALRLPPGSKNYMTRRGYDALRVEL
                     DQLVRVERPRLVETVAWAAGNGDRSENGDYIYGKKRLREIDRRIRFLIKRIESAEVVD
                     PERQQGLEQVFFGATVTFSDLDTEEEQTLQIVGVDEADASQGRISWISPLARAVLKAR
                     VGDVVRFHSPAGVREIEIGAVEYR"
     gene            14226..15860
                     /locus_tag="P5537_07175"
     CDS             14226..15860
                     /locus_tag="P5537_07175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HRV77861.1"
                     /translation="MRFESLTVARRLALMLLVALAGMVLLAFAALYENRDDMRDGYAR
                     NVRSQIELATGVLAHFHSLEQAGALDREAAQKAAKEALRGLRYQNNEYFFVLDLELNM
                     LMHPLRPSLEGKLADLRDSAGKHFVREMVTLARAQGQGFVDYTWPRSGVATDPAQPKL
                     SYVKAFPAWGWVVGSGVYVDDIDTAFQDAALRFGGLVAVVLVLLGLIGAWVIRGVTGA
                     LGGEPAYAGAIMKRAAAGDLAVEVAQRGRGDSLLGNLSTMLAQLRAMIGAIGGSASRL
                     GASAREIHAVSRSVSEASVSQTGATASIAAAIEEMTVSIEQISDSARLAEQHSSTAAG
                     LADEGAGKAERAAREMQAIAARVGDAAQKIQQLVARADEVGTIANVIKEIAGQTNLLA
                     LNAAIEAARAGEQGRGFAVVADEVRGLAERTAVATVQIEKVIEGIQNETRATVGAMAE
                     VSSQVDGGVALVGDATESLHRIRSTAGEALERIREVAYATGEQSSASTEIARQVQTIT
                     EMADGTSGSMHSVVVAAEQLQGLAAELDALVGRFRC"
     gene            15945..17888
                     /gene="htpG"
                     /locus_tag="P5537_07180"
     CDS             15945..17888
                     /gene="htpG"
                     /locus_tag="P5537_07180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HRV77862.1"
                     /translation="MSEVHNPSQPSSQTLAFQAEVKQLLHLMIHSLYSNREIFLRELV
                     SNASDACDKLRFEALDNGALYEDDSELKIRIGFDAEAKTITVADNGIGMSRDEAIAHL
                     GTIAKSGTKEFFGKLTGDQKKDAHLIGQFGVGFYSAFIVADKVTVVSRRAGLPADQGV
                     RWECSMSGDEAGAYTVEAVDKASRGTEITLHLREGQEDLLSSWKLKSLIRKYSDHIVQ
                     PIVMKKEEWDEEQKKQVVTDEDETANQANALWTRAKNDITDDEYTAFYKHVAHDFEDP
                     LAWTHSRVEGRHEYTNLLYVPKNAPFDLWDRNAKHGIKLYVKRVFIMDDAEKLMPTYL
                     RFVRGVVDSADLPLNVSREILQESKDIDTIRAGCTKKVLTLLESLANSDEAADKEKYA
                     EFWKAFGKVLKEGVGEDFANKDKIAGLLRFASTKLDTPDEVVSLADYIGRMKEGQDKI
                     YFVTAETFNAAKNSPHLEVFRKKGIEVLLLTDRVDEWVVGNLTEFDGKALVSVAKGGL
                     DLGALEDEAEKKEAEKAADEYKELLDKMKASLGERVKDVKVTLRLTDSPACLVADEHD
                     LGMNLARILKAAGQSAPVSKPILEINPAHPAVLRLKYEEQHFDDWAAVLFDQALLAEG
                     GTLDDPATFVKRINQLMMAMSGN"
     gene            18096..18863
                     /locus_tag="P5537_07185"
     CDS             18096..18863
                     /locus_tag="P5537_07185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV77863.1"
                     /translation="MSEFILETRGLTKEFKGFVAVSNVDLKVRTGHIHALIGPNGAGK
                     TTVFNLLTKFLPPTSGSILFDGKDITREAPAVTARRGMVRSFQISATFPNLSVLENVR
                     IGLQRRLGTEFHFWRSARSLDALNDEAMALLEAVDLTQFADTVTAEMPYGRKRALEIA
                     TTLALEPRMMLLDEPTQGMGGEDIARVVELIRKVSANRTILMVEHNLSVVANLCDRIT
                     VLTRGSVLAEGSYAEVSKNPKVLEAYVGSDDIADAHH"
     gene            18882..19604
                     /locus_tag="P5537_07190"
     CDS             18882..19604
                     /locus_tag="P5537_07190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011763855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV77864.1"
                     /translation="MTSAFTPHPEMLRIHDLHAFYGESHILHGIDIKVARGECVTLLG
                     RNGSGRSTTLKSVLGLVGKRTGSIMVNGREVIAEPTHRMARYGIGYVPEERAIFASLS
                     TEENLMLPPQVASGAMSVEEIYRMFPNLQERRNSPGSKLSGGEQQMLAMARVLRTGAK
                     LLLLDEITEGLAPVIVKKLGEVIVELKSRGFTIVLVEQNFRFAAPLADRHYVLEHGEI
                     IATISAEELPGKMDWLHQTLGV"
     gene            19662..20876
                     /locus_tag="P5537_07195"
     CDS             19662..20876
                     /locus_tag="P5537_07195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HRV77865.1"
                     /translation="MHMKKLTTLACAAAFAMLSGAASAQISGNTVKIGVLTDMSGTYS
                     DLAGAGAVLATQMAIEDFIAEAKPAFKVEMVSADHQNKADIASNKAREWFEREGVDTA
                     TELVTTSTALAVMKIAKEMNRVALMSGPASTPITNEQCNDVTVHYTYDTYALANGTAK
                     AVTQQGGNTWFFLTADYAFGQALEKDSSAVVTANGGKVLGSVRHPFPASDFSSFLLQA
                     QASGAKIIGLANAGADTTNAIKQAAEFGVTPKQALAGLLMFISDVHSLGLQATQGMYL
                     TTGFYWDLDDQTRAWSKRFFDKQKRMPTMVQAGQYSSVLHYLRAVQATGSDEAGKVMA
                     QMKATPIKDFFGKNGRIREDGRMVHDMYLAQVKSPAESKYPWDYYHIRQTIPAEEAFQ
                     PLAQSRCPLVKK"
     gene            20948..21829
                     /locus_tag="P5537_07200"
     CDS             20948..21829
                     /locus_tag="P5537_07200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HRV77866.1"
                     /translation="MEIFGVPSALLGSQLLVGLINGSFYAILSLGLAIIFGLLNIINF
                     THGAQYMMGAFVAWIALNKLGINYWVALLFAPIVIGALGVLIERTMLRKLYKLDHLYG
                     LLLTFGLALIFEGIFRDQYGISGQSYPVPELLQGGVNLGFMFLPIYRGWVVVAALTVC
                     FATWFVIEKTKLGAYLRAGTENPQMVQALGINVPLLITFTYGFGVALAAFAGVLAAPV
                     YQVSPLMGSNLIIVVFAVVVIGGMGSIMGSILTGLGLGLIEGLTRVFYPEGSAVVVFV
                     IMVVVLLVRPAGLFGKA"
     gene            21853..22806
                     /locus_tag="P5537_07205"
     CDS             21853..22806
                     /locus_tag="P5537_07205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HRV77867.1"
                     /translation="MNNSNSMFARATPILFGALFLIGLVAPFAVYPTFLMKILCFGLF
                     ACAFNLLLGFAGLLSFGHAAFLGSAGYVCGMLVRDVGVTPELGILGGTLAAGVLGWVF
                     GVLAIRRTGIYFAMITLALSQMVYFIVLQWKATGGEDGLQGVPRGQLFGVIDLSNNIA
                     MYYLVFAVFCIGFFIIYRAIHSPFGQILKAIRENEPRAVSLGYDVAKFKLLAFVLSAA
                     LAGMAGATKTLVFQLASLTDVHWHMSGEVVLMTLLGGLGTVLGPLVGAATIVSLQTEL
                     ADSVGSWVTVIMGTIFVVCVLLFRRGIVGELQALIRRAGIR"
     gene            complement(22771..24381)
                     /locus_tag="P5537_07210"
     CDS             complement(22771..24381)
                     /locus_tag="P5537_07210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HRV77868.1"
                     /translation="MSNAPDPAPVAQADGTAAATPPEPGDPPPSGPPGSPATPGIAAR
                     GRAFARLLRGGRRYALPWLSLRRWRVRLLLVGAALLAGLIAIAFAIGAELAIATHAGL
                     IRERPWLTLLIAPAGFAALAWISRRFFHGTEGSGIPQAIAASMSDDGQVRRQLLSLRI
                     ALAKVFLTLGGLLSGASVGREGPSVQVGASVMHLLASRKRHRRIASSRDLIVAGSGAG
                     IAAAFNTPLGGIMFAIEEMCRYRAFQANSTTLTAVIFAGLMSLAVLGNYTYFGRTLAS
                     LGWPDGIWPVLACGVAGGLLGGIFTRILVASARGLPGRLGRVAAGQPVAFAAMCGLLT
                     ALIGLASGGVTYGTGYAESKAALEGSAALPVAFTLMKMAVIWLVFASKIPGGIFAPAL
                     AVGAGLGSDLALLLPGEQDAAILVLGMVAFLAAMTQTPITSFVIVMEMTANHQMLLPL
                     MATAVVAHGVARSVAPVPLYHALSHPWLRRAEKRVHEKRQRPAHPPEGAQGAGAPKTA
                     AEPAAGPTAQPAPKPPSSADAGAPDQGL"
     gene            24567..25070
                     /locus_tag="P5537_07215"
     CDS             24567..25070
                     /locus_tag="P5537_07215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HRV77869.1"
                     /translation="MAETQQKVKKPVAPATPLSVLQRFRILIRTAQRHSQWIERQSGV
                     TGAQLWALQELREAPGLRVGELANRMALHQSTTSNMVDRLETSGLIRKERTSADQRVV
                     RLYLTDEGLALLARAPSPARGVLPEALRLMDDEGLASLQSELEKLLRQIKNLDEGFGM
                     QPLPFTE"
     gene            complement(25185..26864)
                     /locus_tag="P5537_07220"
     CDS             complement(25185..26864)
                     /locus_tag="P5537_07220"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009975 - cyclase activity [Evidence IEA];
                     GO_process: GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HRV77870.1"
                     /translation="MALPPVDRNPRPDHGRAHVPDDARWPGARDAGLVASPLSRTHRD
                     TQPAAMDETELPCPFCKASNTRPIIDADGAWSARCEECGARGPIAADARAALSHWERV
                     TGERALLRMVIDESPDLILLKDGDGRFMLCNAALAHLYGTTPEQLVGKDDAALPGNTG
                     RIGLGLESVRAVTYGDSVQIVEESALHAETGELRHFHSIRKPVLGLADEPCMLVIAHD
                     ITALKRAHRAIEERERSYAHAMEAAGEGIWNWDIEAGTLTHNRRWCELLGHAPDTFVH
                     PIAAFSDSLHPDDRDEVLTRLDEALAGTGSYEHEHRLRRPDGSMVWVLDRGRVVERAP
                     DGRPLHMAGTITDISARKHNEFVLSLATDALANANAKLERKVAERTADLARANEELAR
                     LARRDALTGLPNRLAVEERLHEETLRRPARRSSASAVLMIDIDFFKPINDTHGHATGD
                     EVLAQVARLLAATVRESDFVGRYGGEEFLVLLPETTLEGARTVAEKLRDIVERTPHPA
                     AGRMTISIGLAMAEKINGELAAVMAQADAALYEAKRTGRNRVVVASQSGTA"
     gene            complement(26750..27928)
                     /locus_tag="P5537_07225"
     CDS             complement(26750..27928)
                     /locus_tag="P5537_07225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HRV77871.1"
                     /translation="MLIDFFLHLKARKLPVSTREFLTVLEGLRDHVCGPSLDDFYYYA
                     RLCLVKDESLYDRFDQAFGEYFKGVTALPGLEADLPEDWLRAMARKHLSPEERAKLEK
                     LGWDKLMEEFRKRLQEQKGRHQGGSKWIGTGGSSPFGNNGTHPEGIRVGGESAGNRTA
                     VKVWDKREFRNLDDSVELGTRNIKVALRRLRRFARQGAAEELDLDGTIAATARNAGWL
                     DLMMRPERHNAVKVLLFLDVGGSMDDHVKVCEELFSACRLEFKHLEYFYFHNCVYEGV
                     WRDNRRRHAERTPLLDVIHKYGSDYKLIFVGDATMSPYEILHPHGSVEHMNAEAGATW
                     LRRLLDAYPAAAWLNPEPERLWPYRQSIGILGQIMGERMYPMTLDGLARAMQALSRRH
                     "
     gene            complement(27951..29342)
                     /locus_tag="P5537_07230"
     CDS             complement(27951..29342)
                     /locus_tag="P5537_07230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDOD domain-containing protein"
                     /protein_id="HRV77872.1"
                     /translation="MFRALFGWLFGRKPASPPAAPSEAEGFRRLQREAPLRAEEPPAG
                     ASEAGATFLCREAVLGRNQRIAGYQFMLQEATRARIRHSSRRIHHVYAEVLVRSLVNA
                     DIGELLGERLAFIDLPDSFLSHPSLAALPARNVVIVPTVLADAGAPEPAALRANVAAL
                     RERGFRLGLIDPTVVAELAHLLPQTEFIVAQAEGLDARRGLKLGNIALEVAHDARLVV
                     RGLPSLDDFRFCCKLGASLFQGPFITSREDWSARDPGPNTARIGTLIARLRADADTRE
                     LAGLLKQDAALSLRLLRYINSAANALPQPVSSIEHALALLGREKLQRWLILLACTVDK
                     AEGRGGAALETALVRGRMMELLGADRPAAERDALFLVGLLSLIDVILQVPLDKALAPL
                     ALGSGIEAALRGEGGPYQALLALAVACEHGAGAADAGGDRLRAAAEACGIAPEQASEC
                     HLQALSWAMQIQD"
     gene            complement(29359..>29868)
                     /locus_tag="P5537_07235"
     CDS             complement(29359..>29868)
                     /locus_tag="P5537_07235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002930131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HRV77873.1"
                     /translation="VLIDEIDKADIEFPNDLLRELDRMEFHVYETRQTIQARHRPIVF
                     ITSNNEKELPDAFLRRCFFHYIRFPDRDTMQRIVDVHFPGIKKALLTEAMEVFFGLRD
                     IPGLKKKPSTSELIDWLKLLVAEDIPPEALRSTDGKAAIPPLHGALLKNEQDVHLFER
                     LVFMARHNR"
BASE COUNT         4526 a        10027 c        10780 g         4535 t
ORIGIN      
        1 gcgaacacca ccagcgcgag cgcgatccag ccgcgcccgg cgaccatgcc ctcggcccac
       61 atcggcgtgt agaacaccga caggaaggcg ccgccgacgc cggccatggc gccgccgaag
      121 agcaccgcca ggtagcggat gcggatcacc ggatagccga tcgcgtgcgc agaggacggg
      181 gcctcgccga ccgcgcgcag caccagtccg gcgcggctgc ggtgcaggaa ccacagcagg
      241 ccccagaaca gcgcccagga gaaataaacc agcgcctgct ggttgtagag cgcctcgccg
      301 atcagcggca ggtcggcgat gaaggggatg cggatcggcg gcaccgcctg cagcgccacc
      361 gcctcgtagg gcttgccgac gaaggccgcg aggccgacgc cgaagatcgc cagggcgagg
      421 ccggaggcga cctggttggc catcagggtg agcgcgagca cgccgaagat cgccgccatc
      481 gccatgcctg cgcccacgcc ggcggccacg cccagccagg ggttgccgct ctcgtgggtg
      541 acggcgaagg cggcgaccgc gcccatcgcc atcatgccct cggcgccgag gttgagcacc
      601 ccggccttct cgttcaccag caggccgagg gcgacgatga tcagcggcgt gcccgccacc
      661 acggtggcga acagcatcga ggtgaacagc cctgcgtcca tcgcggcctc ctcaggcgcc
      721 acgccggcgc aggcgcaggc ggtagtggat gaagacgtcg gcgccgagca ggaagaacag
      781 cagcatgccc tggaacacca tcgagatcga attgggcagg ttgaggtatt gctgcgcctg
      841 ctcgccgccg atgtagagca gggccatgag caggctggcg agcaggatgc cgaaggcgtt
      901 gaggcggccg acgaaggcga cgatgatcgc ggcgaagccg tagccgctgg cgaccttgtc
      961 ggtgagctgg cccatcggcc cggcgacctc gcccattccg gccagcccgg cggcggcgcc
     1021 gccgagcagc aggcccaccc agatcatgcg ggtggccgag aagccggcgt agcgcgccgc
     1081 gtcgaccgcc tcgccggcga cccgcatgcg aaagccggcg tggctgcggt tcatgaaggc
     1141 gtagccggcc accagcgcgg cgagcgcgat cgcgaagccg aagtgcaggc gggtgccctc
     1201 gatcaccatc ggcaacgtgg ccgcctcggc gaacatgcgc gtctgcggga agttgaagcc
     1261 gtcggggtcc ttccaggggc cgaacaccag ccaggacacg aagagctggg ccacatacac
     1321 cagcatcagc gacaccagga tctcgttggc gttgaagcgc gtgcgcagca gcgccgggat
     1381 cgccgcccac gcggcaccgc ccgcggcgcc ggcgaggacc atcgccggca gcaccagcgc
     1441 gctctccgag tcgccgaagt agagcgccac cccggtggcg gccaccgcgc cgagcatgaa
     1501 ctggccctcg gcgccgatgt tccacacgtt ggcgcggaag ccgatcgcca ggccgatcgc
     1561 gcacagcatc agcggcgtgg ccttgagcag cagctcggag agggcgtaga ggtccttgac
     1621 cgggttgagg aagaagacac ggaagccctc gaccgggtcc ttgccgagcg cggcgaacac
     1681 cgccaggccg cctgccagca tcagcgccac cgcgagcagc ggcgaggccc aggacatcag
     1741 ccgcgagggt tcggcgcggg cttcgagctc aagcatgcgg ggtctccatc gcgagcgggg
     1801 cgtccgccgt gtccccggcg cccggccaca gcccgctcat ccacacgccg atgtcctcga
     1861 tggaggtgtc gccggcggcg cgcaccggcg acagccggcc cttggcgatc acggcgatgc
     1921 ggtcgcagat ctcgaagagc tcgtcgagct cctccgagat caccagcacc gcacagccgc
     1981 ggttgcgcag gtcgatgatc tgctggcgga tgaaggcggc ggcgcctacg tccacgcccc
     2041 aggtgggctg cgcgcacacg agcaggcgcg gcgcctgcag gatctcgcgg ccgacgatga
     2101 acttctgcag gttgccgccc gacagcgact tggccgcggc cgccgggcca ccgcacttga
     2161 cgttgaagtc gtcgatgcag cgcctcgcga aggcgcgcgc gcgctcgaag cgcaggaagc
     2221 cggccgtcac caggccctgg ttgtgcgcgg cggtgaggag cgcgttgtcg gcgagcgaca
     2281 tcgtcggcac cgcgccgcgg ccgaggcgct cctcgggcac gaaggccatg ccgagccggc
     2341 gtcgacgccc gggcgacagc cggccggcct cgacaccgca gatctgtacg ggaaatcgct
     2401 ccgccagcgg ctcctcgccc gagatcacgc gcagcagctc ctgctggccg ttgcccgaaa
     2461 cgccggcgat gccgacgatc tcgccggcgt gcacatcgag gtggaggtcg cgcaggtcgg
     2521 tgccgaaggg gtcgtccgag gcgtgcgaca gtccggccag gcgcaggcgg acctcgccgc
     2581 cggcctgcgg cgcgtcgtgc tcgcagcgcg gcagctcctt gccgatcatc aggcgcgcca
     2641 tcgaggcggg tgtctcctgc gccgggatgc actcgccggt gaccctgccg ccgcgcagca
     2701 cggtggcggt gtggcagagc tcgcggatct cgtcgagctt gtggctgatg tagagaatgg
     2761 agcagccctc gtcggcgagc cggcgcaggg tctcgaagag cttgcgcacg gcctgcgggg
     2821 tgagcaccga ggtgggctcg tccatgatca gcagacgtgg gtcctgcagc aggcagcgga
     2881 cgatctcgac gcgctggcgt tcgcccaccg acagggcgtg gatgtggcgg cgcggatcga
     2941 ccggcaggcc gtagcgcgcc gacacctcga cgatacgctg cgcgagcgcg tcgagcgcgg
     3001 gcttgccggg cagggccagc gccacgttct cgaccacggt gagcgtctcg aacagcgaga
     3061 agtgctggaa caccatgccg atgcccaggc tgcgcgcgtg cgcggggctc tcgacctgga
     3121 cctcctcgcc ctcccagaac atgcgcccgc tgctcggccg ggtgacgccg tagatgatct
     3181 tcatcagcgt cgatttgccc gcgccgttct cgccgaggat ggcgcggatc tccccggcgc
     3241 gcaccgtcag gccgatgtcg tcgttggcga ccaccgtcgg atagaccttg ccgatgccct
     3301 gcaggaccag ccgtgcgggg gcggcggcgc tgggctgcgg gggggtgagc gggggcagga
     3361 tgggcacgtc tttcaggttt cgtcgatcgg gatgcggagc gggcgctgtc cgggcacccg
     3421 cgtgctcagc ggctgccgtc ttcctgcccg gctgcggctt cgcccttggc cgcctcggcc
     3481 tcggcggcct cgagcgacag ggcttgggcc cggtgcagct cgtccgcgcc gagcttcacc
     3541 gcgatgctgt cgcgctcctg cacaccttcc atgttgagca gcgcggcggc ccgattgaac
     3601 cacacatagg cctgcaccgc atcctgttcc acgccgatcc cgctgcgatg caggcgaccg
     3661 aactccacca tgccctcggg atcgccggcg ttggcagcgt cgcccagcca gcgcgcggcg
     3721 agcgcatagt tctgtggcat gccaatgccg ctgcggtaga gcttgccgag caggaccatt
     3781 gcgccggtgt gcccgccctc cgcggcctgg cgaaggcggt tcaccgcgtc cgaggagacc
     3841 tcgcgtccgc gcgccgtgtc gagcagtgcg gcgcgagcgg cgcggaactg ggcgtcgagc
     3901 gcgtcggtgg gtaaggaggc gtcggccgcg gccgactccg gctccccgcc tgggagggga
     3961 tcgtcgcggt cgagcatcga cacggtggcg atgccgatcg cgagcagcga cagcaaggac
     4021 aggattccga ccaccagcgg ccacttgcgc cctggcccgg ccgcgtcgtc gggaccgatg
     4081 aagcgcttgt cgcagctcct gcagcgccag gggtgcaatc caggatgact cttgtgttcc
     4141 tcgtgcgagc gccagcgcga gcgccggcaa tcgatggagc cgcaggcggg acaggtcggg
     4201 gtcgggaggg gagtgctcat ggcgccgtcc tcgtcagctc ttccagatcc acaggatcac
     4261 gatcacggcg atggtgagca gcagtgtgcc gccgcccacc gcggccacga tcgggttgtc
     4321 gcgcaggagg ccgcgcgata ccggggcgtg aaagcggtgt acgcaggaca tgcagcgcca
     4381 ggcgcgctcg cccgggtggg cgaggcgctc atccgcggat ttccacgggg attcgcggca
     4441 gtcggtgccg tcgcagcgcg ggcaggtggg catgggatcg ttggtgcggg cggtggtcgc
     4501 agggcggacc gcgtactgtt tctgaagatt ttcgcgatta tatagagcgt cggcgcggga
     4561 tgaaggatcg tgcgttcgtg ccgaaagcaa aaaggcagcc tgcggaggct gccttcttgc
     4621 cggacgggtg tgcgcgcagc gccgcgcggc gtcctcagcc gcaggtgccc accgcgccgc
     4681 acgcggtgca gaagtcgcag ccgtccttgc ggatcaccgt gtggttgccg cactcgttgc
     4741 acagcgcgcc ctgcatcagc ttgggctcgt tgtcgtcgcg cggcgactcg aggatgccca
     4801 tctcgcgcgt cgggtagccg cgctcgtcga gcacgccgag catggcgtag cggtggatga
     4861 tgagctgcgc caggtaggcc accgtgctgg gccagttctg ctggcggcgg gtgcccggca
     4921 cgaaggccat gaagtcgccg agcggctcgg ggtagtcgag cagcttgcgc agcttcatgc
     4981 cgatccaggc cgggtccatg acgcgcatgt cgagcgacag gatgcgggtc aggccgtcca
     5041 gggcgcgcgg gtagttgccc gacagccaca ccgagtaggg gcgggtgaca ccgtccggca
     5101 aggtgatttc cttgagaccg aggacgaagt cttcaccggt ggccgggttg tagatgtcca
     5161 ccgtccacga cagcgtgccg tcggtgccgg tcttgggctc ctcgaggctg aacagggtgt
     5221 cgagtacgcc gttgctctcg tcttccttgt cgaacacgcc gagcttctcg cagcggtagt
     5281 tcaccacctg ggcgaaggcc gacaccacgc cgggcaccag cttcttctcg ccgtgcggcg
     5341 ggaagggcat ctcgaaggag cgttcgccca cggtgcgggc cagggtgtcg agcttcaact
     5401 tgagccagcc gcggtcgttg gcgcgcatgt ccatcgacag cgtcttggcc acggcgccca
     5461 ggccgcgcgg ctggtcggcg ccgttcaccc acacctcgaa cgggaagctg ccgccgttgt
     5521 tgccgacctg gccgacgaag agcgcgaagc cgccggtcgg ggtgttgagc atgtaggtcc
     5581 acgccaggtt gccatcgggc aggtcggggc ggccgggcca gcgcaggctc gagagcaccg
     5641 gcgcgggcag gttcttgatc gacaggcgct tgttggcgtc ggcgatctcg acgtcgtgcg
     5701 gctgcttctg ctcggcggtc ggggtcaccg acagcaccga tcccagcacg ttgttggggc
     5761 ggtaggtggc gagacccttg aggccggcct tccaggcggt gaggtagagg tcctcgaact
     5821 cggcgtaggg gtagtcctcg ggcacgttca ccgtcttcga gatggacgtg tcgacgtagg
     5881 gcgcgaccgc ggcgaccatg tccttgtgcg cctgcgcgga gatctccagc gcggtgacga
     5941 aggactgcgg cagagcctcg acgttgccgc cgaggtgctt gtacaggcgc caggcgtagt
     6001 cctcgaccgc gtactccttg aaggtgccgt cggccatgcg cttgcgccgg gtatacgtat
     6061 aggagaacgg cggctcgatg ccgttggagg cgttgtcggc gaaggccagg ctgatcgtgc
     6121 cggtgggcgc gatcgacagc aggtgcgagt tgcggatgcc gtgcttgcgg atcttgtcct
     6181 tgacgtcggc cggcaggcgc gaggcgaagt tgccgcccga cagatacagg tcggcgttga
     6241 agagcgggaa ggcgccgcgc tcgcgggcga gctcggtcga ggccaggtag gcgcggttgc
     6301 gcatgtactc ggagatcctg cgcgcctcgt cgcgggcttc cggggtgtcg tagcgctggc
     6361 cgagcatgat cagcgcgtcg cccaggccgg tgaagccgag gcccacgcgg cgcttggact
     6421 gggcctcggc gtgctgctgc tcgagcggcc agtgggtgac ctcgagcacg ttgtcgagca
     6481 tgcggatcga ggtgtcgatc accttgccga aggccgcgta gtcgaactcg gccttgtcgc
     6541 cgaaggggtt cctgacgaac agcgtgaggt tgatcgagcc caggcagcag cagccgtagg
     6601 gcggcagcgg ctgctcggcg caggggttgg tggcctcgat ggtctcgcag taatacaagt
     6661 tgttgtccgc gttcatgcgg tcgaggaaca ggatgcccgg ctcggcgtgg tcgtaggtcg
     6721 agcgcatgac ctggtcccac agctcgcgcg cgcgcacctt gcggtacacc cacaggccgt
     6781 cgtcgcgctg gtaggcgccg gcggacttga cctcgtcggt gggctcggcc ttgtgcacca
     6841 gctcgacgtc gccgtcggcc tcgacggcct gcatgaaggg gtcggtgacg cccaccgaga
     6901 tgttgaagtt ggtgaggtcg ccttcgtcct tggcgtggat gaattcctcg atgtcggggt
     6961 ggtcgcagcg cagcacgccc atctgtgcgc cgcggcgggc gccggccgat tccaccgtct
     7021 cgcacgagcg gtcgaacacg cgcatgtagg acaccgggcc ggaggcgttc gacgccgtgc
     7081 ccttgaccag cgcgcccttc ggacggatcg acgagaagtc gtagccgacg ccgccgccac
     7141 ggcgcatggt ctcggcggcc tgggcgagcg cggtgtagat gccggggcgg ccgtcgaccg
     7201 cctcggtgac cgagtcgccg accggctgca cgaagcagtt gatcagggtg gcggcgagcg
     7261 tggtgccggc ggcgctgttg atgcggcctg cgggcacgaa gcccttttcc tgcgcctcga
     7321 ggaacttcgc ttcccagtgc gcacgcttgt cttcggattc gatcgcggcc agcgcacggg
     7381 cgacgcggcg gcggacttcg gcgacggtct gttcgtcgcc cttggcgtac ttctcgacga
     7441 gcacctcgcc ggagatctcc tgcatcggca ggttggcggc ggaggctttg gcggtgttct
     7501 gggtggacgc gctggtggtc tcgctcatgg tcttcttctt catccgttgt gggtcttggg
     7561 acggacggaa ggatagcgcg gaacgagtgc tcgtgcaaaa aaataaaact gtttaaaaac
     7621 agtgtcttat agatttgctt tgtatttcat gattttgctg aacactacat atagtagcct
     7681 ggagggtagg gttttcaggc tggaatccca gtctccatgc gggtttgcgg gggttttgag
     7741 gccgcctacc ggcgcgggaa gaacagcgac aggtaggcgg cgaaatcgat ctccgcgcct
     7801 tcgcgcaggc cggcgaggcg ctcgggctcg agcccgagca gatcccaggt ctcggctgcg
     7861 acccgggtcg cggcggcgct gctcgggagg tccagctcgt cggcttcggc gatgcagcgg
     7921 gcgaggttga ccgtcgccgc ctctgcggcg taggcgccgc ccaggcgggg cagcatctgc
     7981 gcgcccaccg cggtgctgaa gcgctccggc agctgccagc ggtcgagcag ggcggcgccg
     8041 agctcggcga aatcgcagcc gacgatgcgg cgctcggcgg cgtcgagcgc ctcctcgccg
     8101 gcttgcgccg cgaggcgtgc ggcggcggcg tgctcgggca cggtctggta catcaccagg
     8161 tggccggtgt cggcgagcac gccgatcagg aacaggcgct cgcctgcggt gagcccggcg
     8221 gcgaccccag cggcgcgcgc ggccagcccg gtgagcaggc tgttgcgcca gaagcgccgc
     8281 atgtccaggt gggccgggcg gacgccggcg aagatgccct gcagggacat cgccagcacg
     8341 agatcgtgca cctgctgcag gccgagcagc gcgaccgcgc gcacgatgtc ctcgacgcgg
     8401 ccgcgctggc cgaacagcgg gctattgacc agatgcagca ggcgggccga gagcgccggg
     8461 tcggcggcga ccagccgtgc gacggtggcg accgagccgg cgggggattc gagctgctcg
     8521 cgcacgcgca tgtacacgtc gggcagcgag gtcagcgcct cgatctggct gaccagttcc
     8581 tgggcggagt gcattgtcgg ggtcctgtgg atcggtggag gggctcagcc ggcgtcgtgc
     8641 gtgcgccgca tgcggggggt gaagaccagc ggctgcgccg gcggcagctc gggctgcagg
     8701 gtggcgtgct cgatgccgaa gcggccgtgc aggagggcgc gctcggcctc cagcaccgcc
     8761 ggccagcgcg ccgcatcggc gagcacgaca tgggcggaga gcgcggtacg gcgcgagtcc
     8821 aggctccaga tatggaggtc gtgcaccgag cgcacgccct cgacgcccgc catcgcgcgc
     8881 ccgacctcgg gcagcgacag gctgtcgggc acgccctcga gcagggtgtg gaccacctgg
     8941 cgcagcagcg acagcgtgga gtacaggatc aggccgcaga tcatcatggt cagcagcggg
     9001 tcgatcggca tccagccggt atacaggatc acgatccccg aggcgagcgc ggcgaccgag
     9061 ccgagcaggt cgccgatcac gtgcagcagc gcgccccggg tgttgaggtc gccctcgccg
     9121 cgggtcagca gccaggccac ggccaggttc agcaccagcc cgccgagcgc gaccaggatg
     9181 accgcctcgc cggccaccgc gcgcggctcg agcaggcgct cgaccgcgtg ccacaccagg
     9241 ccgccgacga tcaccagcat gaagagcccg ttggcgagtg cggcgagcgc ctcgacccgg
     9301 cgcaggcccc aggagtggcg gacgctggtc gggcgcagcg cgatgcgcgc cgcgagcgcc
     9361 gccagcccga gcgaagcggc gtcggtgagc atgtggccgg cgtcgccgag cagcgcgagc
     9421 gagcccgacc accagccggc gatcgcctcg accaaggcga agcccagcgt gagcacgagc
     9481 gcgagcggca ggaagcggct ggcggagtgg tcgtgggcgt ggtgatggtg accgccgtga
     9541 tgccgatgcg cttgctcgtg ctcgtacccg tgcccgtgtt cggggccgcc atggtcgtcg
     9601 tcgggggtgt ggtgctcatg agcggagtgg agatgcatcg tagcgcttcc tcgatgggta
     9661 ccgaggatta tgcctgcggt gccgcccggc ccggcagggc gggcgtccgt ggcggtaggc
     9721 ggcgcgggcc cgcagcggcc cgccgggact cagcgctgca gcagccccga gaagcgctcc
     9781 accacgttga cgactgcggt ggcgccgttg tggatgccgt cgatgacctc gccggcctcg
     9841 cgcgcgaggt cgatgctcgc agtcgccgtc tcgtgcatgc catgcacccg cgagatggcc
     9901 aggtgggtgg cgtcctgcac ggtggagatc atcgcgctga tctcggtggt ggccctggag
     9961 gtgcgttcgg cgagcttgcg cacctcgtcg gcgacgaccg cgaagccgcg cccgtgctcg
    10021 ccggcgcggg cggcctcgat cgccgcgttg agcgcgagca ggttggtctg gtcggcgatc
    10081 tcgcggatgg tgttgacgat ggtggtgatg cgtccggttt cgtcgccgag ctgtccgaag
    10141 gtgtgcacgg catcctcggc gctgtcggag atcgccacca tctgcgtggt ggcgcgtgcg
    10201 atcacgtcgg ttccgcgctc ggcaaggtgg gcgttgtcgc gtgcgcgttc gagcgcggcg
    10261 gcggcgttgg cgatctcttc ctcgagcgcc tccacgcggc tgctgatgtc ggaggcgagc
    10321 ttgatgaact tgcacggtcg acccgcctcg tcgaaaaccg ggttgtagct ggcctcgagc
    10381 cagaccgtgc ggccgttgcg cgcgacgcgg cggaagcggc cggagaagta ctcgccgtgg
    10441 cgcaggcgct cccagaatcg cgcgtagtcg ggtgcctcgg cgtcctcggc ggcacagaac
    10501 aggcgatggt ggcggccgag cacctcgcca cgggcgtagc ccatggtggc caggaagttg
    10561 tcgttggcgg cgagcacctt gccgtcgagg tcgaactcga tcatcgccat cgagcgctcg
    10621 atcgcggcca gcatggcgcg gcgctctgcc ccctcgcgca tctgggcggt gatgtcggtg
    10681 gcgagcttga ccacgcgcag cacgcggccg tcggggccga acaccgggtt gtaggtggcc
    10741 tcgagccaca ccggctcgcc gctggcgtcg cggcgctcga agcgcccgct caccggctcg
    10801 ccgcggcgca ggcgttgcca atgcgcgaga taatccgacg agttcgcgta accctcctcg
    10861 cagaacatgc ggtgattctt cccgagcacg tcttcgctgc gatacttcat ggtggcgagg
    10921 aagagctcgt tggcgaacag cacggtgccg tcgggcgcga actcgatgcg cgcggtggtg
    10981 cggtcgatcg cgtcgatcac cgcctggcgc gcggcgagct cggcctgttg ttcctggagg
    11041 gtggtcttga gcttgcggtt gagcatggtc tggtggccgt cgtcgggagt cgcgatggca
    11101 ggcggccgct ggccgcctgc ccggatgcgc ggcatgtcgg gcggggaggc ggcggggcgg
    11161 cgcgcccgcg ccggacacgg ggcgtgtccg gtataacggc gcgccggggt gtttctttac
    11221 attatgtcca aacacatatg aagaagacga ccgggcagcg caaacgaggc atccgcctgc
    11281 tgagctggaa catccagtgg gggcgcggcg cggacgggcg ggtggatctg gagcgcacgc
    11341 gcgacacgat ccgcgccgcc ggtccgctcg atgtgatctg cctgcaggag gtggcgagca
    11401 atttccccgg cctcgccggc ggcgcgcgcg aggacgagcc ggccttcttc gccgcggcct
    11461 tcgcggattt cgagccggtg ttcggtgcgg gcatggacgt gcccgacggc gagggcggcc
    11521 gggcgcgctt cggcaacctg ctgctgtcgc gcctgccggt ggggcaggtg ttccgccacc
    11581 tgctgccgtc gcccgccgac cccgcctggc cggcgatgca gcgggtgtgc gtggaggcgg
    11641 tggtggaggc gccgtggggg ccgctgcgcg tgatgagcac ccacctggag tattactccg
    11701 cgcgccagcg ccgcgcccag gtcgaggcct tgcgcgcgct gcaggccgag gccgccgacc
    11761 tggcgcggct gccggcggcg ggcaaggagt cgaaccccgc cttcgccgcg cgcccgcgcc
    11821 cggccgcggc ggtgctgtgc ggcgacttca actgcgagcc gggctcggcc gaacacctcg
    11881 cgctgcagcg cccgctgccc gcgtccgggc tcgcaccgga cgcccaccgc ccgcactggg
    11941 tggatgcctg gccgatcgcg cacggcgcgc gtgcgcacgc acccagcgtg ggcttgcacg
    12001 gcgcggagtg gcccgaccgc gcctactgct gcgacttctt cttcgtgacc agcgacctgg
    12061 cgccacgggt gcacgcgctc gaggtgctcg cggacaccgc ggcgtcggac caccagccgg
    12121 tggtgattga actggcgtga ggcgtgaggg gggctgttgg ccgccccgcg aggctcagtc
    12181 gctccagagc agggcgcgca ccacggcggc cgggtcctct tcctgcatcg cgtggccgca
    12241 gccaggcagc tcgacccgcc tcacctcgcc accgccggct cgcagggctt cgtgcagcgg
    12301 gccgatggcc ttgaccgggg tcatgcggtc gagcgcgccg cacagcagca gggtggggca
    12361 gtcgcggcgc gtggcggcgg ccagcccgtc ctgccaggcg ttgcaggcgg cgaggtcgtg
    12421 tgcgagcgtc tcgctgccgt tgcgttccat gcgcgcgcgg ttgccggcct cgagcgcgcg
    12481 ccggcgctcc tcgccgagca cctcggcggg ggcgaaggag aacttgttga tcagcgcgtg
    12541 tgcctgcgca gggtcgctgc gcgcggcgtc gagcaggaag ggcgcgaccg gcatcggtgc
    12601 gaggctgccg agcaggtgca ggcggatgat gcgcgccggc gcggccgccg cggcggcgag
    12661 cgcgatcagc gagcccatgc tgtggccggc gagttcgaag cgctccagtc ccgccgcgtc
    12721 ggcgaaggcg agcacccatg ccgccatggt gtcgaccgcg cccgccgcct cgcctgcaga
    12781 gtcgccgtgg ccgggaaggt cggggacgat cacccgccgg ccggcggcgg ccagcccggc
    12841 ggtgaccgcc tgccagactc cgcggtcgtg tccggcgcca tggatcagca ggatggccgg
    12901 cgcggtggcc aggccggact cgtcgaaggc ggcgcggcgg ccgtcgagct ggagggtgcg
    12961 ggtcatgggc gtgttcgtgg agggttcggg agggacgggc agcgggtgtg tccgcgtccg
    13021 cctgggcgct gcgcggcgcc gggacggctg tgcgccgctt caggcgggtg gtcgcccagg
    13081 cgctcgaatg ttcgaaagag cgggggcttc gccgcgtcga agctcaggcg tattcatccg
    13141 ggtccagcat gtgctcgatc gccacgatgc ggtccttgag cgcgagcttg cgcttcttga
    13201 gccggcgcag catgagctcg tcctcgaccg ggttgtcggc gaggcgggcg atcgcgtcgt
    13261 cgaggtcgcg gtgctcgagg cgtaactcct ccagccgttg gcgcaggctg gtcacatcgt
    13321 cgaagctctc cccgctcatg ctcgttcccc tggcgtgcgc gccgcgccgt gggcgaagtg
    13381 ccgggcggcg tcgttttgcc ggcaatggta tgcggcggcg cgggcgctga caacacgacc
    13441 gccagcgcgg tcccgaccgg ggcgggaaac gtcgcgaagc ttccccggcg ggcgccgatt
    13501 tcttaccatg cgcccctcga taccgaccgg aacgtgcaag tgaacaaggc cttcgtgaag
    13561 gagagcgatg gcaacgacga ggacgaggaa ctcgctcccg cgttgcgcct gccgccgggc
    13621 agcaagaact acatgacgcg gcgcggctac gacgcgctgc gcgtggagct cgaccagctc
    13681 gtgcgcgtcg agcgccccag gctggtcgag accgtggcct gggccgcggg caacggcgac
    13741 cgctcggaga acggcgacta catttacggc aagaagcgcc tgcgcgagat cgaccgccgc
    13801 atccgcttcc tgatcaagcg catcgagagc gccgaggtgg tcgaccccga gcgccagcag
    13861 ggcctggagc aggtcttctt cggtgccacc gtgaccttca gcgacctcga caccgaggag
    13921 gagcagaccc tgcagatcgt cggcgtggac gaggccgacg cctcgcaggg gcgcatcagc
    13981 tggatctcgc cgctggcgcg cgcggtgctc aaggcgcgtg tcggcgacgt ggtgcgcttc
    14041 catagccccg ccggcgtgcg cgagatcgag atcggtgcgg tggagtatcg ctgaggggtg
    14101 gagtttcatc caggatgcat agggctcaag tcgggccgaa tgctgccgta gaccggacga
    14161 agcggttgcg cgccacggcg gtgcgccacc gtgcaaaagc tccctctcgt ggatggtccg
    14221 gcaagatgcg tttcgaatcc ctcaccgtcg ctcggcgcct ggcgctgatg ctgctcgtcg
    14281 ccctcgcagg catggtcctg ctcgcgttcg cggccttgta cgaaaaccgc gacgacatgc
    14341 gcgacggcta cgcgcgcaac gtgcgcagcc agatcgagct cgccaccggg gtgctcgcgc
    14401 atttccacag tctggaacag gccggcgcgc tcgaccgcga ggcggcgcag aaggccgcga
    14461 aggaagcgct gcgtggcctg cgctaccaga acaacgagta cttcttcgtg ctcgacctcg
    14521 agctgaacat gctgatgcac ccgctgcgcc cctcgctcga gggcaagctc gccgacctca
    14581 gggacagcgc gggcaagcac ttcgtgcgcg agatggtgac gctggcgcgc gcgcaggggc
    14641 agggtttcgt cgactacacc tggccgcgtt ccggggtcgc caccgacccg gcccagccca
    14701 agctcagcta cgtgaaggcc ttcccggcct ggggctgggt ggtcggctcg ggcgtgtatg
    14761 tggatgacat cgacaccgcc ttccaggatg cggcgctgcg cttcggtggc ctggtcgcgg
    14821 tggtgctcgt gctgctcggg ctgatcggcg cctgggtgat ccgcggggtc accggtgcgc
    14881 tcggcggcga gccggcctac gccggcgcga tcatgaagcg cgccgccgcc ggcgatctgg
    14941 cggtggaggt ggcgcagcgc gggcggggcg acagcctgct cggcaacctc tcgaccatgc
    15001 tcgcgcagct gcgcgccatg atcggcgcga tcggcggcag cgcgtcgcgc ctgggtgcca
    15061 gcgcgcgcga gatccacgcg gtgtcgcgct cggtgtccga ggcctcggtc tcgcagaccg
    15121 gcgcgaccgc ctcgatcgcc gcagccatcg aggagatgac cgtgagcatc gagcagatct
    15181 ccgacagcgc ccgcctggcc gagcagcact cgagcaccgc agcggggctc gccgacgagg
    15241 gcgcgggcaa ggccgagcgc gcggcgcgcg agatgcaggc catcgccgcg cgcgtgggcg
    15301 acgcggcgca gaagatccag caactcgtcg cacgcgccga cgaggtcggc accatcgcca
    15361 acgtgatcaa ggagatcgcc ggccagacca acctgctcgc gctcaacgcg gccatcgagg
    15421 ccgcccgcgc cggcgagcag gggcgcggct tcgcggtggt ggccgacgaa gtgcgcgggc
    15481 tggccgagcg caccgcggtg gccaccgtgc agatcgagaa ggtgatcgag ggcatccaga
    15541 acgagacccg cgccaccgtc ggcgcgatgg ccgaggtttc gagccaggtc gatggcggcg
    15601 tcgcgctggt cggcgacgcg accgagtcgc tgcaccgcat ccgcagcacc gcgggcgagg
    15661 cgctcgagcg catccgcgag gtggcctacg ccaccggcga gcagagcagc gcctccaccg
    15721 agatcgcccg ccaggtgcag accatcaccg agatggccga cggcacctcg ggctcgatgc
    15781 acagcgtggt ggtggcggcc gagcagctgc agggcctggc cgccgagctc gacgccctgg
    15841 tcggacgctt ccgctgctga tccgcatgcc ggcggcgctt gaaatccgcc gccgcgcccc
    15901 caactgctgc tccgtttcga caacctccga cggagcagct tccaatgtcc gaagtccaca
    15961 acccttcgca accttcctcc cagacgctgg ccttccaggc cgaggtgaag caactgcttc
    16021 acctgatgat ccactcgctg tattccaacc gtgagatctt cctgcgcgag ctcgtctcca
    16081 acgcctccga cgcctgcgac aagctgcgct tcgaggcgct cgacaacggc gcgctctatg
    16141 aagacgacag cgagctgaag atccgcatcg gcttcgacgc cgaggccaag acgatcaccg
    16201 tcgccgacaa cggcatcggc atgagccgcg acgaggccat cgcccatctc ggcaccatcg
    16261 ccaagtcggg caccaaggag ttcttcggca agctcaccgg cgaccagaag aaggacgccc
    16321 acctcatcgg ccagttcggc gtcggcttct actccgcctt catcgtcgcc gacaaggtca
    16381 ccgtggtttc gcgccgcgcc gggctccccg ccgaccaggg cgtgaggtgg gaatgctcga
    16441 tgagcggcga cgaggccggc gcctataccg tcgaggccgt cgacaaggcc agccgtggca
    16501 ccgagatcac cctgcacctg cgcgagggcc aggaagacct gctgtcctcg tggaagctca
    16561 agagcctgat ccgcaaatac tccgatcaca tcgtgcagcc gatcgtgatg aagaaggagg
    16621 agtgggacga ggagcagaag aagcaggtcg tcaccgacga ggacgagacg gccaaccagg
    16681 ccaacgcgct gtggacgcgc gccaagaacg acatcacgga cgacgagtac accgccttct
    16741 acaagcacgt cgcccacgac ttcgaggacc cgctggcgtg gacccactcg cgcgtcgagg
    16801 gccgccacga atacaccaac ctgctctacg tgccgaagaa cgcgcccttc gacctgtggg
    16861 accgcaacgc caagcacggc atcaagctct acgtgaagcg cgtgttcatc atggacgacg
    16921 ccgagaagct gatgccgacc tacctgcgct tcgtgcgcgg ggtggtggat tcggccgacc
    16981 tgccgctcaa cgtgtcgcgc gagatcctgc aggaatcgaa ggacatcgac accatccgcg
    17041 cgggctgcac caagaaggtg ctgacgctcc tcgagagcct ggccaacagt gacgaggccg
    17101 cagacaagga gaagtacgcc gagttctgga aggccttcgg caaggtgctc aaggaaggcg
    17161 tgggcgagga cttcgccaac aaggacaaga tcgccggcct gctgcgcttc gcctcgacca
    17221 agctggatac gcccgacgag gtggtgtcgc tcgccgacta catcggccgc atgaaggaag
    17281 gccaggacaa gatctacttc gtcaccgccg agaccttcaa cgccgccaag aacagcccgc
    17341 atctcgaggt cttccgcaag aagggcatcg aggtgctgct gctcaccgac cgcgtcgacg
    17401 agtgggtggt gggcaacctc accgagttcg acggcaaggc gctggtgtcg gtggccaagg
    17461 gtggcctgga cctgggcgcg ctcgaggacg aggccgagaa gaaggaagcc gagaaggccg
    17521 ccgacgagta caaggagctg ctcgacaaga tgaaggcgag cctgggcgag cgcgtcaagg
    17581 acgtgaaggt gacgctgcgc ctgaccgact cgcccgcctg cctggtggcc gacgagcacg
    17641 acctcggcat gaacctggcg cgcatcctca aggccgccgg ccagagcgcg ccggtgtcga
    17701 agcccatcct cgagatcaac cccgcccacc ccgcggtgct gcgcctgaag tacgaggagc
    17761 agcacttcga cgactgggcc gcggtgctgt tcgaccaggc cctgctcgcc gagggcggca
    17821 cgctcgacga cccggccacc ttcgtcaagc gcatcaacca gctgatgatg gcgatgagcg
    17881 gcaactgatc cggctccggg ccgggactgc cactgcaacg ggcgacgcgc cgaaaaggcg
    17941 gtcgcccgtt gtctcttcgc gggcggcgtg ccttgcccgg cggcaccgcg cgggatccgg
    18001 cccgccctgc aaattggggc aaaccatagg ttgacgcacc tcctgccggc cggaacactg
    18061 cccgcataaa aacgaacccc gggcaggaga cacccttgag cgagttcatt ctcgaaaccc
    18121 gcggactcac caaggagttc aagggcttcg tcgccgtatc caatgtcgat ctgaaggtgc
    18181 ggacggggca catccacgcc ctgatcggcc ccaacggcgc gggcaagacc acggtcttca
    18241 acctgctcac caagttcctg ccgccgacct cgggatccat cctgttcgac ggcaaggaca
    18301 tcacgcgcga ggcgccggcg gtgaccgcgc gccgcggcat ggtgcgctcc ttccagatct
    18361 ctgcgacctt ccccaacctc agcgtgctcg agaacgtgcg catcggcctg cagcgccggc
    18421 tgggcaccga gttccacttc tggcgctcgg caaggtcgct cgacgcgctc aacgacgagg
    18481 cgatggcgct gctcgaggcg gtggacctga cccagttcgc cgacaccgtt accgccgaga
    18541 tgccctacgg acgcaagcgc gcgctcgaga tcgccaccac gctcgcgctc gagccgcgca
    18601 tgatgctgct cgacgagccc acccagggca tgggcggcga ggacatcgcg cgcgtggtcg
    18661 agctcatccg caaggtctcg gccaaccgca ccatcctgat ggtggagcac aacctctcgg
    18721 tggtcgccaa cctgtgcgac cgcatcaccg tgctcacccg cggcagcgtg ctcgccgaag
    18781 gcagctacgc cgaggtgtcg aagaacccca aggtgctcga ggcctacgtc ggctccgacg
    18841 acatcgccga cgcccaccac tgatccccgc ccccgaccgc catgaccagt gccttcaccc
    18901 ctcacccgga gatgctccgg attcatgacc tgcacgcctt ctacggcgag tcgcacatcc
    18961 tccacggcat cgacatcaag gtggcgcgcg gcgagtgcgt gaccctgctc gggcgcaacg
    19021 gctccggtcg ctcgacgacc ttgaagtcgg tgctcggcct ggtcggcaag cgcaccggct
    19081 cgatcatggt caatggccgc gaggtgatcg ccgagcccac ccaccgcatg gcgcgctacg
    19141 gcatcggcta cgtgcccgag gagcgcgcga tcttcgcctc gctcagcacc gaggagaacc
    19201 tgatgctgcc gccgcaggtg gcgagcgggg cgatgtcggt ggaggagatc taccgcatgt
    19261 tccccaacct gcaggagcgc cgcaacagcc ccggctccaa gctctcgggc ggcgagcagc
    19321 agatgctggc gatggcgcgc gtgctgcgca ccggggccaa gctgctgctg ctcgacgaga
    19381 tcaccgaggg cctcgcgccg gtgatcgtga agaagctcgg cgaggtcatc gtcgagctga
    19441 agtcgcgcgg cttcaccatc gtgctggtgg agcagaactt ccgcttcgcc gcgccgctgg
    19501 ccgaccgcca ctacgtgctc gagcacggcg agatcatcgc caccatcagc gccgaggagc
    19561 tccccggcaa gatggactgg ctgcaccaga cgctgggggt ctgagcggcc gcgccgcgca
    19621 gtccccgcgt gacaaccaca cgaacgagac ggagacccac gatgcacatg aagaaactca
    19681 ccaccctggc ctgcgcggcc gccttcgcca tgctgtcggg cgccgccagc gcgcagatct
    19741 cgggcaatac cgtcaagatc ggcgtgctca ccgacatgtc gggcacctat tccgaccttg
    19801 ccggcgcggg ggcggtactc gccacccaga tggcgatcga ggacttcatc gccgaggcca
    19861 agccggcgtt caaggtcgag atggtctccg ccgaccacca gaacaaggcc gacatcgcct
    19921 ccaacaaggc gcgcgaatgg ttcgagcgcg agggcgtcga caccgccacc gagctggtga
    19981 cgacctcgac cgcgctcgcg gtgatgaaga tcgccaagga gatgaaccgc gtcgcgctga
    20041 tgagcggccc ggcttcgacg ccgatcacca acgagcagtg caacgacgtg acggtgcact
    20101 acacctacga cacctacgcg ctcgccaacg gcacggccaa ggcggtgacc cagcagggcg
    20161 gcaacacctg gttcttcctc accgccgact acgccttcgg ccaggcgctg gagaaggact
    20221 cgtccgcggt ggtgacggcc aacggcggca aggtgctcgg ctcggtgcgc catccgttcc
    20281 cggcttcgga tttctcctcc ttcctgctcc aggcccaggc ctcgggcgcc aagatcatcg
    20341 gcctcgccaa cgccggcgcc gacaccacca acgcgatcaa gcaggcggcc gagttcggcg
    20401 tcacgcccaa gcaggcgctc gccggcctgc tgatgttcat ctccgacgtg cactcgctcg
    20461 gcctgcaggc cacccagggc atgtacctga ccaccggctt ctactgggac ctcgacgacc
    20521 agacccgtgc ctggtccaag cgcttcttcg acaagcagaa acgcatgccg accatggtgc
    20581 aggccggcca gtactcctcg gtgctgcatt acctgcgcgc ggtgcaggcc accggctcgg
    20641 acgaggcggg caaggtcatg gcgcagatga aggccacgcc catcaaggac ttcttcggca
    20701 agaacgggcg catccgcgag gatgggcgca tggtgcacga catgtacctg gcgcaggtca
    20761 agagcccggc cgagtccaag tacccgtggg actactacca catccgccag acgattcctg
    20821 cggaggaggc cttccagcct ctggcgcagt cgcgctgccc gctggtgaag aaataagctg
    20881 atcgcggggg ctcccgcact tcacgacgca gcggggcggc acggccgtcc cgctgcggga
    20941 gtcgcacatg gaaatcttcg gcgtcccgag cgcgctgctc ggcagccagt tgctggtcgg
    21001 cctcatcaac ggttcgttct acgcgatcct gagcctaggc ctggccatca tcttcggcct
    21061 gctcaacatc atcaacttca cccacggcgc ccagtacatg atgggcgcct tcgtggcgtg
    21121 gatcgcgctc aacaagctcg gcatcaacta ctgggtggcg ctgctgttcg cgcccatcgt
    21181 catcggcgcg ctcggtgtgc tgatcgagcg cacgatgctg cgcaagctct acaagctcga
    21241 ccacctctac ggcctgctcc tcaccttcgg cctggcattg atcttcgagg gcatcttccg
    21301 cgaccagtac ggcatctccg gccagtccta cccggtgccc gagctgctgc agggcggggt
    21361 gaacctcggc ttcatgttcc tgccgatcta ccgcggctgg gtcgtggtcg ccgcgctgac
    21421 ggtgtgcttc gcgacctggt tcgtcatcga gaagaccaag ctcggcgcct acctgcgcgc
    21481 cggcaccgag aacccgcaga tggtgcaggc gctcggcatc aacgtgccgc tgctgatcac
    21541 cttcacctac ggcttcggcg tcgccctcgc cgctttcgcc ggggtgctgg ccgcaccggt
    21601 gtaccaggtg agtccgctga tgggttcgaa cctgatcatc gtggtgttcg ccgtggtcgt
    21661 gatcggcggc atgggctcga tcatgggctc catcctcacc ggcctcggac tggggctcat
    21721 cgagggcctc acccgggtgt tctaccccga gggctcggcg gtggtggtgt tcgtgatcat
    21781 ggtggtcgtg ctgctggtgc ggccggccgg cctgttcggc aaggcctgag cgcgcggaga
    21841 ggaatcagac tgatgaacaa ctcgaattcg atgttcgcac gtgccacccc gatcctcttc
    21901 ggcgcgctgt tcctgatcgg gctggtggcg ccgttcgcgg tgtatcccac cttcctgatg
    21961 aagatcctgt gcttcgggct gttcgcctgc gcgttcaacc tgctgctcgg cttcgccggc
    22021 ctgctctcat tcggccacgc cgccttcctc ggcagcgccg gctacgtgtg cggcatgctg
    22081 gtgcgcgacg tcggcgtgac gccggagttg ggcatcctcg gcggcacgct cgccgcgggc
    22141 gtgctcggct gggtgttcgg cgtgctggcg atccgccgca ccggcatcta cttcgcgatg
    22201 atcacgctgg cgctgtcgca gatggtttac ttcatcgtgc tgcaatggaa ggcgaccggc
    22261 ggcgaggacg gcctgcaggg cgtgccgcgc ggccagctct tcggcgtgat cgacctgtcg
    22321 aacaacatcg cgatgtacta cctggtgttc gcggtgttct gcatcggctt cttcatcatc
    22381 taccgcgcca tccactcgcc cttcggccag atcctcaagg cgatccgcga gaacgagccg
    22441 cgcgcggtct cgctcggcta cgacgtggcg aaattcaagc tgctggcctt cgtgctctcc
    22501 gccgcgctcg ccggcatggc gggcgccacc aagaccctgg tgttccagct cgcctcgctg
    22561 accgacgtgc attggcacat gtcgggcgag gtggtgctga tgacgctgct cggtggcctc
    22621 ggcaccgtgc tcggcccgct cgtcggcgcc gccaccatcg tgtcgctgca gaccgagctc
    22681 gccgacagcg tgggctcctg ggtcacggtg atcatgggga cgatcttcgt ggtctgcgtg
    22741 ctgctgttcc gccgcggcat cgtcggcgag ctacaggccc tgatccggcg cgccggcatc
    22801 cgctgaggac ggaggtttcg gggccggctg cgcggtcggc cctgcagccg gctccgcggc
    22861 tgtcttcgga gcgccggcgc cttgcgcacc ctcgggcggg tgggcggggc gctggcgctt
    22921 ttcatgcacg cgcttctcgg cgcggcgcag ccaggggtgc gagagtgcgt ggtagagcgg
    22981 caccggcgcc accgagcgcg ccacgccgtg ggccaccacc gcggtggcca tcagcggcag
    23041 cagcatctgg tggttggcgg tcatctccat gacgatcacg aaggaggtga tcggggtctg
    23101 cgtcatcgcg gcgaggaagg ccaccatgcc cagcaccagg atcgccgcgt cctgctcgcc
    23161 cggcagcagc agcgcgaggt ccgagccgag gccggcaccc accgcgagcg cgggggcgaa
    23221 gatgccgccg gggatcttcg aggcgaagac cagccagatc actgccatct tcatcagcgt
    23281 gaaggccacc ggcagcgccg cgctgccctc gagcgcggcc ttggattcgg catagccggt
    23341 gccgtaggtg acgccgccgc tggccaggcc gatcagcgcg gtcagcaggc cgcacatcgc
    23401 cgcgaaggcg accggctgac ccgcggcgac cctgccgagg cggccgggca ggccgcgcgc
    23461 ggacgccacc aggatccggg tgaagatgcc tccgagcagg cccccggcca cgccgcaggc
    23521 gagcaccggc cagatcccgt cgggccagcc caggctcgcc agggtgcggc cgaagtaggt
    23581 gtagttgccc agcaccgcga gcgacatcag gccggcgaag atcaccgcgg tgagcgtcgt
    23641 gctgttggcc tggaaggcgc ggtagcggca catctcctcg atcgcgaaca tgatgccgcc
    23701 gagcggggtg ttgaaagccg cggcgatgcc ggcgccgctg ccggcgacga tgaggtcgcg
    23761 gctcgaggcg atgcggcggt ggcgcttgcg gctggcgagc aggtgcatca ccgaggcgcc
    23821 gacctgcacc gaggggccct cgcggcccac cgaggcgccg ctgagcagcc cgcccagggt
    23881 caggaagacc ttggccagcg cgatgcgcag cgacagcagc tggcggcgaa cctgcccgtc
    23941 gtccgacatc gacgccgcga tcgcctgcgg gatcccgctg ccctcggtgc cgtggaagaa
    24001 gcgtcgtgag atccaggcca gcgcggcgaa gccggcgggg gcgatcagca gggtgagcca
    24061 ggggcgctcg cggatcagcc cggcgtgggt ggcgatcgcc agctcggcgc cgatggcgaa
    24121 ggcgatcgcg atcagcccgg cgagcagcgc cgcccccacc agcagcaggc gtacccgcca
    24181 gcgccgcagc gacagccagg gcagggcgta gcggcgcccg ccgcgcagca ggcgggcgaa
    24241 ggcgcgacca cgcgcggcga tgccgggtgt agcgggcgag ccgggtggcc cggacggtgg
    24301 cggatcgccc ggttcgggcg gcgtggccgc tgccgtgcca tcggcctgcg cgactggggc
    24361 ggggtccggt gcgttgctca tcggaggctg tgctgccatg cgggattcct tcccggcgaa
    24421 gtggacggcg gcagcatttt caaaggcttt tctgtaatgc tgcacatgcg aagaccgaac
    24481 gataccgcta ccatacgcgt cgttgcacgg cgtgatgttt ttttgacaat cattgtttgc
    24541 gtaaatatag ttccagcgag actcgaatgg cggaaacgca acagaaagtg aagaagccgg
    24601 tggctccggc gacccccctg tcggtcctgc agcgcttccg gatcctcatc cgcaccgcgc
    24661 agcgccactc ccagtggatc gagcgccaga gcggggtcac cggcgctcag ttgtgggcgc
    24721 tgcaggaact gcgcgaggcg cccggcctgc gggtgggcga gctcgcgaac cggatggcgc
    24781 ttcaccagtc caccacctcg aacatggtgg accggctcga gacctcgggg ctgatccgca
    24841 aggagcgcac cagcgccgac cagcgcgtcg tgcggctgta tctgaccgac gaggggctgg
    24901 cgctgctggc gcgcgcgccg tcgccggcgc gtggcgtgct gcccgaggcc ttgcgcctga
    24961 tggacgacga gggcctcgcc agcctgcaga gcgagctcga gaagttgctg cgccagatca
    25021 agaatctcga cgaaggcttc ggcatgcagc cgctgccctt caccgaatga atggcggtcc
    25081 gcccggcgcg gtctgcctcg accgtgcttc agacgaagtg accgcactcg tgcggacagc
    25141 agattcggcg gcccaggagg ccgccatttt tttgccggtc ggtctcaggc cgtgccggac
    25201 tgcgacgcaa ccaccacgcg gttgcggccg gttcgcttgg cctcgtacag cgcggcatcg
    25261 gcctgcgcca tcaccgcggc cagttcgccg tttatcttct cggccattgc caggccgatc
    25321 gagatcgtca tcctgcccgc cgctgggtgt ggcgtcctct ccacgatgtc gcgcaatttc
    25381 tcggccaccg tgcgcgcacc ctcgagcgtg gtctcaggca gcagcacgag gaactcctcg
    25441 ccgccgtagc gtcccacaaa atccgattcc ctcaccgtgg cggcaagcag gcgcgcgacc
    25501 tgggcgagga cctcgtcgcc ggtcgcatgc ccatgggtat cgttgatcgg cttgaagaag
    25561 tcgatgtcga tcatcagcac agcgctggcg ctgctgcgcc gcgcgggccg gcgcagcgtc
    25621 tcttcgtgca ggcgctcctc gaccgcgagg cggttgggga gccccgtcag tgcgtcgcgg
    25681 cgggcgaggc gggcgagttc ctcgttggcg cgagcgagat cggcggtacg ctcggcgacc
    25741 ttgcgctcga gtttggcgtt cgcgttcgcg agtgcgtcgg tcgcgagcga aagcacgaat
    25801 tcgttgtgct tgcgtgcgct gatgtcggtg atcgtgccgg ccatgtgcag cgggcggccg
    25861 tcgggtgcgc gctcgacgac gcggccgcgg tcgagcaccc aaaccatgct gccgtcgggg
    25921 cgacgcagcc tgtgctcgtg ttcgtagctg cccgtgccgg cgagcgcctc gtcgagccgg
    25981 gtcagtacct cgtcgcgatc gtccgggtgc agactgtccg agaaggcagc gatcgggtgc
    26041 acgaaggtgt cgggagcatg gccgagcaat tcgcaccagc gccggttgtg ggtgagcgtg
    26101 ccggcctcga tgtcccagtt ccagatgcct tcgccggccg cctccatggc atgggcgtag
    26161 ctgcgctcgc gctcctcgat cgcccgatgc gcgcgcttca gcgcggtgat gtcgtgcgcg
    26221 atcacgagca tgcacggctc gtctgccaga ccgagcacgg gcttcctgat cgaatggaag
    26281 tggcgcagtt cgccggtttc ggcatggagc gcgctttcct cgacgatctg cacgctgtcg
    26341 ccgtacgtca ccgcacgcac gctttcgagg ccgaggccta tccgccctgt gttgccgggg
    26401 agggcggcat cgtccttgcc gacgagctgt tcgggcgtgg taccgtacag gtgcgcaagt
    26461 gcggcgttgc agagcatgaa gcggccgtcg ccgtccttga gcaggatgag gtcgggcgat
    26521 tcgtcgatca ccatgcgcag cagcgccctc tcgccagtca cccgttccca gtgcgacagc
    26581 gccgcccggg cgtcggccgc gatcgggccg cgtgcgccgc attcctcgca gcgtgcgctc
    26641 caggcgccgt cggcatcgat gatcggtcgg gtgttgctgg ccttgcagaa ggggcagggg
    26701 agctcggttt cgtccatggc cgctggctgg gtatcccggt gcgtgcggct cagtggcgac
    26761 gcgacaaggc ctgcatcgcg cgcgccaggc catcgagcgt catcgggtac atgcgctcgc
    26821 ccatgatctg gccgaggatt ccgatcgact ggcggtaggg ccacaggcgc tcgggctcgg
    26881 gattgagcca ggcggccgcc gggtaggcgt cgagcaggcg gcgcagccag gtggcgccgg
    26941 cttcggcgtt catgtgctcg accgagccgt gcggatgcag gatctcgtag gggctcatgg
    27001 tggcgtcgcc gacgaagatc agcttgtagt cggagccgta cttgtggatc acgtcgagca
    27061 gcggcgtgcg ctcggcgtgg cggcggcgat tgtcgcgcca cacgccctcg tagacgcagt
    27121 tgtggaagta gaagtactcg aggtgcttga actccagccg gcaggcggag aagagctcct
    27181 cgcacacctt gacgtggtcg tccatcgagc cgccgacgtc gaggaagagc agcaccttga
    27241 ctgcgttgtg gcgctcgggg cgcatcatca ggtcgagcca gccggcgttg cgcgcggtgg
    27301 cggcgatggt gccgtcgagg tcgagctcct cggcagcgcc ctggcgggcg aagcggcgca
    27361 gccggcgcag cgcgaccttg atgttgcgcg tgccgagctc gaccgagtcg tcgaggttgc
    27421 ggaactcgcg cttgtcccac accttgaccg cagtgcggtt gccggcggac tcgccgccca
    27481 cgcggatgcc ctcggggtgg gtgccgttgt tgccgaaggg cgagctgccg ccggtgccga
    27541 tccacttgct gccgccctgg tggcgtcctt tttgctcctg caggcgcttg cggaactcct
    27601 ccatcagctt gtcccagccg agcttctcga gcttggcgcg ctcctcgggc gagaggtgct
    27661 tccttgccat cgcgcgcagc cagtcctcgg gcaggtcggc ctccagtccc ggcagcgcgg
    27721 tgacgccctt gaagtattcg ccgaaggcct ggtcgaagcg gtcgtagagc gactcgtcct
    27781 tcaccaggca cagccgcgcg tagtagtaga agtcgtcgag cgaggggccg cacacgtggt
    27841 cgcgcaagcc ctcgagcacg gtgaggaact cgcgtgtcga caccggcagc ttgcgggcct
    27901 tcaggtgcag gaagaagtcg atcagcatgg ggcctcccct tcgtgcatgc tcagtcctgg
    27961 atctgcatgg cccaggacag ggcctgcagg tggcattcgg aggcctgctc gggcgcgatg
    28021 ccgcaagcct cggcggccgc acggagccga tcgccgcccg cgtccgccgc acccgcgccg
    28081 tgctcgcatg ccaccgcgag ggcgagcagg gcctggtagg gaccgccctc gccgcgcagc
    28141 gcagcctcga tcccgctgcc cagcgcgagc ggcgccagcg ccttgtccag cggcacctgc
    28201 aggatcacgt cgatcagcga cagcaggccg accaggaaga gcgcatcgcg ctcggccgcc
    28261 ggacggtcgg cgccgagcag ttccatcatg cggccgcgca ccagcgcggt ctcgagcgcc
    28321 gcgccgccgc gcccctcggc cttgtccacg gtgcaggcga gcaggatcag ccagcgctgc
    28381 agcttctcgc ggccgagcag cgcgagcgcg tgctcgatcg aggacaccgg ctgcggcagc
    28441 gcgttggcgg cggagttgat gtagcgcagc aggcgcagcg acagcgccgc gtcctgcttg
    28501 agcagcccgg cgagctcgcg cgtgtccgcg tccgcgcgca ggcgcgcgat cagggtgccg
    28561 atgcgtgcgg tgttggggcc ggggtcgcgc gcgctccagt cctcgcggct ggtgatgaag
    28621 gggccctgga agaggctggc cccgagcttg cagcagaagc ggaagtcgtc gagcgatggc
    28681 agcccgcgaa ccaccaggcg cgcgtcgtgc gcgacctcga gggcgatgtt gcccagcttg
    28741 aggccgcggc gggcgtcgag gccctcggcc tgggcgacga tgaactcggt ctgcggcagc
    28801 aggtgggcga gctccgcgac cacggtggga tcgatcaggc cgaggcgaaa gccgcgctcg
    28861 cgcagcgcgg ccacgttggc gcgcagggcg gcgggctcgg gggccccggc gtcggcgagg
    28921 acggtgggca cgatcaccac gttgcgcgcg ggcagggcgg cgaggctggg gtgggacagg
    28981 aaggagtcgg gcaggtcgat gaaggccagg cgctcgccga gcagctcgcc gatgtcggcg
    29041 ttgaccaggc tgcgcaccag cacctcggca tagacgtggt ggatcctgcg gctgctgtgg
    29101 cggatgcgcg cgcgggtggc ctcctgcagc atgaactggt agccggcgat gcgctggttg
    29161 cgcccgagca ccgcctcgcg gcacaggaag gtggcgccgg cctcgctcgc gcctgcggga
    29221 ggctcctcgg cacgcagcgg cgcctcgcgc tggaggcggc ggaaaccctc cgcctcgctc
    29281 ggcgcggcgg gcggagaggc aggcttgcgg ccgaacagcc agccgaacag ggcgcggaac
    29341 atggttgctc gcgccggctc agcggttgtg acgggccatg aacaccaggc gctcgaagag
    29401 gtgcacgtcc tgctcgttct tgagcagggc gccgtgcagc ggcgggatcg ccgccttgcc
    29461 gtcggtgctg cgcagtgcct cgggcgggat gtcctcggcc accagcagct tgagccagtc
    29521 gatcagctcg gaggtggagg gcttcttctt gaggccgggg atgtcgcgca ggccgaagaa
    29581 gacctccatc gcctcggtca gcagcgcctt cttgatgccg gggaagtgga catcgacgat
    29641 gcgctgcatc gtgtcgcggt cggggaagcg gatgtagtgg aagaagcagc gccgcaggaa
    29701 ggcgtcgggc agctccttct cgttgttcga ggtgatgaag acgatcgggc gatggcgcgc
    29761 ctggatggtc tggcgcgtct cgtagacgtg gaactccatg cggtcgagtt cgcgcagcag
    29821 gtcgttgggg aactcgatgt cggccttgtc gatctcgtcg atcagcac
//
LOCUS       DAOTIN010000034        28911 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_1838_length_28911_cov_9.031536, whole genome shotgun sequence.
ACCESSION   DAOTIN010000034 DAOTIN010000000
VERSION     DAOTIN010000034.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 28911)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 28911)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28911
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1838_length_28911_cov_9.031536"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..498)
                     /locus_tag="P5537_07240"
     CDS             complement(<1..498)
                     /locus_tag="P5537_07240"
                     /EC_number="1.1.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344297.1"
                     /note="NADP-dependent; catalyzes the oxidative
                     decarboxylation of malate to form pyruvate; decarboxylates
                     oxaloacetate; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HRV77874.1"
                     /translation="MDELIRSAALDYHRYPRPGKISVTPTKVLSNQRDLSLAYSPGVA
                     AACDAIVEDPAQAAELTARSNLIGVVTNGTAVLGLGNIGPLAAKPVMEGKGVLFKKFA
                     GIDVFDLEIDEPDADKLIDMIAALEPTFGGINLEDIKAPECFYIEAKLRERMKIPVFH
                     DDQHGT"
     gene            887..2734
                     /locus_tag="P5537_07245"
     CDS             887..2734
                     /locus_tag="P5537_07245"
                     /EC_number="4.1.1.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004611 - phosphoenolpyruvate
                     carboxykinase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0017076 - purine nucleotide binding
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (GTP)"
                     /protein_id="HRV77875.1"
                     /translation="MSQNHAQAAIAAAPEYVRHEGLKKWVGEIAALTEPDRVVWCDGS
                     QEEYDRLCAEMVESGMLIKLNPEKRKNSFLAWSDPSDVARVEDRTFICSQKKEDAGPT
                     NNWEDPAVMRETLNGLFKGCMHGRTMYVIPFSMGPLGSPIAHIGVEISDSPYVVTNMR
                     IMTRMGRGAVEVLGTDAEFVPCVHTVGAPLAQGEKDSRWPCNPTTKYIVHYPETREIW
                     SYGSGYGGNALLGKKCFALRIASTMARDEGWLAEHMLILGVESPEGEKSYVAAAFPSA
                     CGKTNFAMLIPPKSFDGWKITTVGDDIAWIKPGPDGKFRAINPEFGYFGVAPGTSEKT
                     NFNAMATLKENIIFTNVALTDDGDVWWEGMTKEAPAHLVDWQGKDWTPEIASETGRKA
                     AHPNARFTAPASQCPSVDPAWEDPAGVPISAFIFGGRRATTVPLVYQAFNWNFGVYMA
                     STLGSETTAAAFGAQGVVRRDPFAMLPFCGYHMGDYFNHWLRMGHVVEDTPKIFCVNW
                     FRMNEQGQFMWPGFGDNMRVLKWIVDRCKGKIAAKETALGWMPRFEDLDWTGAEVNRE
                     EFEALTKVDADAWRAELNSHKEWFDKLQDRLPRQLVLKRELFELALNAD"
     gene            3127..4302
                     /locus_tag="P5537_07250"
     CDS             3127..4302
                     /locus_tag="P5537_07250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HRV77876.1"
                     /translation="MHRSRRLDDIQPFHVMELLRRARELEAQGRDIIHMEVGEPDFGT
                     PAPVVEAANRFLAGGDVHYTPALGLPALREAIARFYHDRFGADVAPERIVVTAGASGA
                     LMLALAATTDPGDEWLLPDPGYPSNRHLIRAFEGVARALEVDAASRYQPRPGQVDAAW
                     GERTRGLMVATPSNPTGTLLSVAEIAALHRSTRARGGVLLVDEIYQGLTYGVESATAL
                     ADPVLNAADDVFVVNSFSKYFGMTGWRLGWLVAPTGFVRELEKLAQHFFISPSTPAQH
                     AALAAFAPATIAILEERRHEFAQRRDVLLPALRELGFGIATEPQGAFYVYADVSALAD
                     DSEALARRMIEEAGVAATPGLDFGHHLPRRHLRIAYTTRSERLLEAADRIRALGLGR"
     gene            complement(4558..5472)
                     /locus_tag="P5537_07255"
     CDS             complement(4558..5472)
                     /locus_tag="P5537_07255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HRV77877.1"
                     /translation="MKHATRFKALARQAGGAARSLAHGAVLSVSLMGMGWLGTQSGGV
                     TDVRYGDVLSQQAEPTASELAMASVLSFAPRRVEEVAPSFAAAVPSLAASTRLHESLP
                     VAAPGLVERNLARVVAEPVPPVFHQPALRDIAALVDNPFEEEEGALSDEMARVRDWIA
                     DTYRVSEEAIEPALAAAETHAEELGFDPLLIVAIMAVESSFNHRAVSNMGALGLMQVI
                     PRYHKDKIGPNRGRNVLFDPETNVRVGTLVLQEGLERYGSMQRALQYYNGSLKDPKAR
                     YPRKVMALKKRLMLIAGRDSGRDAEQAS"
     gene            complement(5832..6359)
                     /gene="ampD"
                     /locus_tag="P5537_07260"
     CDS             complement(5832..6359)
                     /gene="ampD"
                     /locus_tag="P5537_07260"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,6-anhydro-N-acetylmuramyl-L-alanine amidase
                     AmpD"
                     /protein_id="HRV77878.1"
                     /translation="MKDLTPLSPNHDERPAGEPVRLIVIHAISLPPDQFGGPGVEQLF
                     TNTLDPTAHPYYATIQHLRVSAHYFIRRDGQLLCFVDPARRAWHAGVSCWNGRERCND
                     FSIGIELEGCDTMPFEPAQYERLAALIVELERRYPIEAVVGHSDIAPGRKTDPGPFFD
                     WKRLDVMCKQRRASC"
     gene            complement(6356..7243)
                     /locus_tag="P5537_07265"
     CDS             complement(6356..7243)
                     /locus_tag="P5537_07265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002944683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - transposition, DNA-mediated
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HRV77879.1"
                     /translation="MARPLRIELAGGVYHLTSRGDRREPIYADDVDRLLWLELFGEVC
                     DRFNWRCHAWCQMGNHYHLVVETAEANLSRGMRQLNGVYTQAANRRHARVGHVFQGRY
                     KAILVEADAYLVELARYVVLNPVRAGLCGDAREWPWSSHRALMGLVDPPSWLETDWVL
                     GQFGSERTAAVRRYEDFVRAGVGLPPIWERLNAQIYLGSGAFADEMAHKVPDDGRLDE
                     VPRLQRRPQGMSLQAYVERSASRDAAIAEAAASGAFTLAQLAQFFGLHYSSISRIVAK
                     DRKARQPPGAGNASEQMSK"
     gene            complement(7379..7756)
                     /locus_tag="P5537_07270"
     CDS             complement(7379..7756)
                     /locus_tag="P5537_07270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family
                     toxin"
                     /protein_id="HRV77880.1"
                     /translation="MLVETDVLIWNLRGNARAADRLDAMPGFLVSAVTYMELVQGVRD
                     KSELRALRQALSFWSARVVQVDEAISARACFLCEQFALSHSMQMADALIAATALERGL
                     DLLTANDRHYRHVEQLCIEVFRP"
     gene            complement(7756..7995)
                     /locus_tag="P5537_07275"
     CDS             complement(7756..7995)
                     /locus_tag="P5537_07275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system
                     prevent-host-death family antitoxin"
                     /protein_id="HRV77881.1"
                     /translation="MEATIRDLRLHTAEVLAAADRGERVTITSRGQARAVLMRCEETR
                     ARAHAERNPAFGLWADRQGTVDDDVRRLRQPRVLP"
     gene            complement(8085..8396)
                     /locus_tag="P5537_07280"
     CDS             complement(8085..8396)
                     /locus_tag="P5537_07280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002932341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77882.1"
                     /translation="MQKLLTVSILALAATTAQADPAVMFGINYNFGGGGPGLSVKVLS
                     SDREDRTVASVGASYYPMMNRVGLDVGVGRTFENGAATVSWDVINSAPQASIGFVDTV
                     K"
     gene            8595..8915
                     /locus_tag="P5537_07285"
     CDS             8595..8915
                     /locus_tag="P5537_07285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0001558 - regulation of cell growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PrlF family
                     antitoxin"
                     /protein_id="HRV77883.1"
                     /translation="MPAIHEVATITSKGQITLPKPIRQALGVDVGGKVAFDLTGDRVI
                     VTRATEIAHEDPAIGSFLAILEEDIRSGRHITTLPDDLTRSMLAALGKHADLREDIEG
                     DVAL"
     gene            8912..9367
                     /locus_tag="P5537_07290"
     CDS             8912..9367
                     /locus_tag="P5537_07290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YhaV family
                     toxin"
                     /protein_id="HRV77884.1"
                     /translation="MIQRHGWNLLFHDCLIAQLQKLDAAAARVRAQDPERYESNANTK
                     LFAALANLIFETVPGDPNREEYRQGNTMGPGFRHWRRAKIGRRFRLFFRFDSKTRIII
                     FAWVNDEKTLRSTGAKTDPYAVFQKMLKSGHPPDDWDALLKASKSDWKA"
     gene            complement(9979..10314)
                     /locus_tag="P5537_07295"
     CDS             complement(9979..10314)
                     /locus_tag="P5537_07295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002932339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HRV77885.1"
                     /translation="MNTMNIGGYEAVITFDPDIQMFRGEFVGLNGGADFYAADVAGLR
                     REGDVSLRVFLDACERRGIEPRKRFSGKFSLRVDPAVHEAAVVAAAAHGQSLNQWAAE
                     AIRQAARAG"
     gene            complement(10311..10565)
                     /locus_tag="P5537_07300"
     CDS             complement(10311..10565)
                     /locus_tag="P5537_07300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002944681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HRV77886.1"
                     /translation="MKRKHQRTLELIHARPVSANVRWGDIEALFRELGAEISEREGSR
                     VEVFLFGVVRIFHRPHPSPDTDKGAVAAIRKWLEDNGVQP"
     gene            complement(11101..12177)
                     /locus_tag="P5537_07305"
     CDS             complement(11101..12177)
                     /locus_tag="P5537_07305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porin"
                     /protein_id="HRV77887.1"
                     /translation="MQKKLIALAVAGLVSAPAFAQSNVTIYGVADAAIGLGEHGKNDF
                     NGVINGVLSGSRIGFRGTEDLGNGLKAVFALEQGFDIGNGVASPAVGSNEKATDTDGK
                     TIVDGDSVFSRQAYVGLSGSFGTVSVGRQYAPGYFFNYDAVLGASVGPQSLLSAAGGM
                     TITPNSPARWDNSVAYTGSFSGLTARAIYSMKAVETSLNPEDDDAFGLSVDYANGPLA
                     VGAVYQYLFTDGAEDQEEWGIGGSYDFGMVKVAGSYQAAEGLKFAKGAEADLWQIGVI
                     VPVSAAGNVHLAYGEFDRDDKSNLGAESWSLAYTHALSKRTTAYAAYNQTENESGTMA
                     FGPVAGTANGDDSSVFAVGIRHTF"
     gene            complement(12351..12752)
                     /locus_tag="P5537_07310"
     CDS             complement(12351..12752)
                     /locus_tag="P5537_07310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002932332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family
                     toxin"
                     /protein_id="HRV77888.1"
                     /translation="MIVLDTHVLIWMDADDSALGPQARACIEQAWRAGEVAVSAISFW
                     ECAMLADKGRIVLPLAVESWRAGLLGAGLAEIALDGRIVLAAAGFADLHRDPADRFIA
                     ATAGVRNATLVTADEKLLAWNAGLPRLDARR"
     gene            complement(12749..12979)
                     /locus_tag="P5537_07315"
     CDS             complement(12749..12979)
                     /locus_tag="P5537_07315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HRV77889.1"
                     /translation="MQTIQASEFKARCLALMDQVAASGEILVVTKNGKPVAELHPYQG
                     ARVSSPFGLHPGVRILGDIVSPVADEDWEALS"
     gene            13130..13438
                     /locus_tag="P5537_07320"
     CDS             13130..13438
                     /locus_tag="P5537_07320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011236955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HRV77890.1"
                     /translation="MKVMTAREAKNRFGEFLDASRREPVVITKNDRPVGIMVSIEDAA
                     DTLLPEFLLDKTPGYDGWLFEKVTATLERLDAGQTTLHAHDEAMALLRERVAARNRRA
                     "
     gene            13435..13725
                     /locus_tag="P5537_07325"
     CDS             13435..13725
                     /locus_tag="P5537_07325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HRV77891.1"
                     /translation="MNILWTDEALDDLEEILVYYHSEAGPLTAEAVHSRIVAEIEALR
                     VFPERIRASTRIPGARELVVRRLPYVAFVKVTDDAVIVLNVVHTAREFPSRR"
     gene            13832..14080
                     /locus_tag="P5537_07330"
     CDS             13832..14080
                     /locus_tag="P5537_07330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HRV77892.1"
                     /translation="MRTVSATEAKQGLAGVLDLAAHEPVVIRRQKRDVAVVLSMKEYE
                     RLTRLNVAEFQRFCDAVGEKAAAAGLTEDKVAELLADD"
     gene            14073..14483
                     /locus_tag="P5537_07335"
     CDS             14073..14483
                     /locus_tag="P5537_07335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004521 - endoribonuclease activity
                     [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative toxin-antitoxin system toxin component,
                     PIN family"
                     /protein_id="HRV77893.1"
                     /translation="MTEFLRFVVDTNVLVSRLLAPRSTAAKAVDRALAQGNLLGSEET
                     LAELVEVLARPKFDPYVSREGRREFIRLLGGVMQVVPIIRRVAACRDPRDDKFLDVAL
                     AGEAAAIISEDKDLLVLNPWHGIAILTPAAFIVR"
     gene            14622..14885
                     /locus_tag="P5537_07340"
     CDS             14622..14885
                     /locus_tag="P5537_07340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HRV77894.1"
                     /translation="METLPSRVFNNGNSQAVRIPAEFRLDTDRVSITRNDAGDLVIHP
                     LRVQRGTALMQALKALGEVDDDFVAALEAEQETPLPVQEREAL"
     gene            14882..15301
                     /locus_tag="P5537_07345"
     CDS             14882..15301
                     /locus_tag="P5537_07345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family
                     toxin"
                     /protein_id="HRV77895.1"
                     /translation="MIYLLDTNILIYLIKNQPPGIAQRIDTLPESDTLCMSLVTWAEL
                     LKGAERSTRKTEVLRRLNALAREVPVRYPTAPAICRHYAEQAIRLKEAGTPIGANNLW
                     IACHALAEDATLVTHNTREFRRIAGLRVEDWVSAEKD"
     gene            15390..16241
                     /gene="rpoH"
                     /locus_tag="P5537_07350"
     CDS             15390..16241
                     /gene="rpoH"
                     /locus_tag="P5537_07350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoH"
                     /protein_id="HRV77896.1"
                     /translation="MSQALTFPVPAAGSLDQYIQSVNRMPMLSEQQEVELATRLRDDG
                     DVDAARQLVMSHLRVVVAIARGYLGYGLPHADLIQEGNIGLMKAVKRFDPTRGVRLVS
                     FAIHWIKAEIHEYILKNWRLVKIATTKAQRKLFFNLRGMKQDSSTLQPAEVRSIAAQL
                     GVKPEEVVEMETRLTGRDIPLDAGSDDEDERFAPIAYLPDPHAEPSEQIEQAQLARLQ
                     DSGLRDALASLDERSRAIVQRRWLAEGDSATLHELAAEYGVSAERIRQIEAKAMQKMR
                     GMLAAVA"
     gene            complement(16322..16924)
                     /locus_tag="P5537_07355"
     CDS             complement(16322..16924)
                     /locus_tag="P5537_07355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SCO family protein"
                     /protein_id="HRV77897.1"
                     /translation="MSSRRKAISLLVATPLLALGLLAGCTPAEPVFKSTDISGTSYGK
                     TLRLTDHHGQERTLADFKGKVVTIFFGYTQCPDVCPTALSGMSTVMQELGPEADRVQV
                     LFVTVDPERDTPELLAQYVPVFDARFLGLYGTAEKIAEVAKEFRVFYRKSGDLAGHYT
                     IDHTAGTYVFGPDGRPRLYVKHAEDPQVVVADIKALLAGK"
     gene            complement(17070..17561)
                     /locus_tag="P5537_07360"
     CDS             complement(17070..17561)
                     /locus_tag="P5537_07360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HRV77898.1"
                     /translation="MTDPKLPEPLPAAASTPEPVRQSPALRLACFYETLTPAALDGLD
                     QFYAPDARFKDPFNEVAGTAAIRRIFEHMFATTEAPRFEVTDCIEQGGQAMLGWTFHF
                     ALRGRALTVRGVTHLRFDADDRVTLHRDYWDAAEELYEKLPLLGGLMRAVRRRLRATD
                     PPR"
     gene            complement(17572..18486)
                     /locus_tag="P5537_07365"
     CDS             complement(17572..18486)
                     /locus_tag="P5537_07365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HRV77899.1"
                     /translation="MTAPAARRGWFAPLNTPIREWAGRRVWIVGASSGIGEALALELA
                     RRGACLALSARGRERLEAVCAACDAAAGAGPVGGAAPATGNAGSPANAAVEPARRAGS
                     PAAARALALDLSRADELERARDQLLADWGGIDLVVFNAGTYRPLRAWELSAQAVRETL
                     ETNLVGTMSGTAAVLPTLLAQGEGAIALVGSVAGYGGLPKATAYGPSKAALINFAEVL
                     HLDLSPRGIGVFLIDPGFVATPLTAQNDFAMPALQTPAQAADAIVDGFARGDFEIHFP
                     KRFTRVLKFLQLLPRRFYFALIRRATGV"
     gene            complement(18483..19016)
                     /locus_tag="P5537_07370"
     CDS             complement(18483..19016)
                     /locus_tag="P5537_07370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004391165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3833 domain-containing protein"
                     /protein_id="HRV77900.1"
                     /translation="MKRFFLMCVALLGLWGCSSVNIDDYRAETPVLELRDYFDGTIDA
                     WGMFQDRSGKVVKRFHVLIDARWQGDTGTLDEHFTYSDGTTQRRVWTITRLGPGRYSG
                     RADDVVGEATGEAAGNALRWRYVLALPVDGKVYNVDFDDWMFLMDDQVMLNRSLMSKW
                     GFRLGEVTLSFHKRARP"
     gene            complement(19013..20602)
                     /locus_tag="P5537_07375"
     CDS             complement(19013..20602)
                     /locus_tag="P5537_07375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HRV77901.1"
                     /translation="MTEGARVVPDGCAAGDASAGTPGASGIGRARGCGERGDLIAYGA
                     LGLPLAFAALPIYVHVPRLYAEGLGLSLALVGAVLLAARIVDAVTDPLIGWANDRLPR
                     RRLWIALALPALGAGMLGLLVPPAGSGAAWLFGLLVAVSLAYSVASIAYNAWGAEVAA
                     TPAARTRFVASREAFALAGVVLAAALPGLLGDAGMGGEGAGAGAGVVREAEVSAQPAD
                     GAPASVSDGGAAGLARLAWAFLPLLVVFGLWTLWRAPAPPPLAPVRAALWRGLRAALG
                     DAGFARLLAVFAANGIAAAIPSATVLFFVADVLQAEALAGAFLALYFVAAAAGLPVWT
                     RLSQRIGKLRAWLGSMALAVAVFAWAGLLGSGDLVAYACICVLSGLALGADLTLPPSL
                     LADLLARGRERAPSRHLEAVAPIGMTGDARMHDGAACAPTLEAGACFGWWSFVTKANL
                     ALAAGLALPLLALLGYTPGAREAAAVGALAAVYGFVPVALKLAAIALLWRWRDAIEPG
                     GWRASPVPGGVGGKDLRGEQS"
     gene            complement(20599..21231)
                     /locus_tag="P5537_07380"
     CDS             complement(20599..21231)
                     /locus_tag="P5537_07380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016872 - intramolecular lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chalcone isomerase family protein"
                     /protein_id="HRV77902.1"
                     /translation="MNAPTRFPARAPQRLRRGLSRLVRAPRARKARELGVVLACCMLL
                     AMETVHALGLPPQLAASEAGLREIGRGELRWLGFKLYDAALWARAPGAQAMDDEYVLS
                     IRYARAVTSERLVELSLDEMRRLGLADEPTLARWAGALAAALPAVAAGDTLTGLHRPG
                     RGAAFWHDGRPTAELDDPALAQAFFAIWLDERTREPALRARLLGLADGAR"
     gene            complement(21300..22541)
                     /locus_tag="P5537_07385"
     CDS             complement(21300..22541)
                     /locus_tag="P5537_07385"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclopropane-fatty-acyl-phospholipid synthase
                     family protein"
                     /protein_id="HRV77903.1"
                     /translation="MNALDHALQPLAGLRLARLPRATRLCLEMLDRLDGGAIAVELPD
                     GVRVRAGHGPLVAHLRVRDHAVFDEALARGDIGFGETWMDGLWDTEDLPGLLRLLSAN
                     RARLQGAIYGRMFRLLSHRLQHLLRANTRSGSRRNIEAHYDLGNDFYALWLDPTMTYS
                     AAVFASPDESLAHAQLRKYRRILGELGVQPGQTILEVGCGWGGFAEVAATEFGCKVLG
                     ITLSPSQLEFARARAERGGFADRVDFELCDYRDVRGQYDHIVSIEMIEAVGERFWPTY
                     FAQLSGLLKPGGRCVVQAITIADALFARYRRGTDFIQRHVFPGGMLPSPGAVAQQAGR
                     AGLEVVGDFAFGRDYARTLAHWHRSFDAQAAAVRAQGFPERFLRMWRFYLAYCEAGFD
                     TGDIDVHHYVFAHAGAASRAG"
     gene            complement(22541..23311)
                     /locus_tag="P5537_07390"
     CDS             complement(22541..23311)
                     /locus_tag="P5537_07390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1365 domain-containing protein"
                     /protein_id="HRV77904.1"
                     /translation="MSDALQPAVCFGAVMHERHVQAHNRFVYPSAFLRLPLGRLDRVR
                     APLLGIERANLISFRSRDHGARDGSPLLPWIRALLDERGLAAACDGEVVLQTMPRILG
                     FVFNPVSFWFCHDRTGNLRAVLAEVNNTFGERHNYLLHHDDLRPIVAGDELRASKRFH
                     VSPFFPVRGEYRFRFEQRGAVHAVSIELWDGGERQLSTRLSGRAEAVSGASMGKWLAR
                     QPFMTLGVIARIHWQALRLALRRVSFFRKPAPPIEETT"
     gene            complement(23311..24672)
                     /locus_tag="P5537_07395"
     CDS             complement(23311..24672)
                     /locus_tag="P5537_07395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HRV77905.1"
                     /translation="MKMGEIERLHAAGEAGQGSQGRRIAVIGGGIAGLSTAWLLAPQH
                     RVTLFEAGSYVGGHTNTIDVTVDGLTHPVDTGFLVFNRRTYPNLCALFALLQVEAVET
                     EMSFGVSLAEPELEWAGTDLASVFAQRGNLVRPAFLAMLRDILRFNRETTRMAHEGAM
                     PALSLGEYLDLEDYSQAFRDWYLLPMAAAIWSCPTRTMLAYPLATFVQFCHNHGLLQI
                     LDRPTWMTVKGGGRSYVRRMLARLDDVRVNSPVQRVVRGEDGVWVHTAGGAERFDELV
                     FACHSDQALAILGSEATAEERRVLGAVQYQANVAWLHTDTALLPRRQKVWSAWNYLAG
                     KGAPDARPVSVSYLINRLQPLPFQTPVVVSLNPFTEPAADKTFRRIEYAHPVFDHGAI
                     DAQAALPAIQGRERCWFAGAWTGYGFHEDGLKSAVAVVEAMGVEVPWRRGRVPAAMAL
                     EAA"
     gene            complement(24678..25484)
                     /gene="folE2"
                     /locus_tag="P5537_07400"
     CDS             complement(24678..25484)
                     /gene="folE2"
                     /locus_tag="P5537_07400"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003933 - GTP cyclohydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0035998 - 7,8-dihydroneopterin
                     3'-triphosphate biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase FolE2"
                     /protein_id="HRV77906.1"
                     /translation="MNAPEKFFLPDVQSSADHRALAIQQVGVRGLRYPIAVRDLDGGV
                     QHTVATLEMTVGLPADVKGTHMSRFVELLEAERDALDLDGLRGLFADMLLRLEASSGR
                     IEARFPWFMKKAAPVSGVESLLDIDARVVVEKAEGGEIRSTLEAVVPVTSLCPCSKKI
                     SAYGAHNQRSHITLSATLRGDLGLRELVRMAEEEASCEVFGLLKRPDEKWVTERAYDN
                     PKFVEDLVRDIALRLRADARVASWRVQSENFESIHNHSAYALIEGENAPE"
     gene            complement(25481..25735)
                     /locus_tag="P5537_07405"
     CDS             complement(25481..25735)
                     /locus_tag="P5537_07405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77907.1"
                     /translation="MNANTLSRRAGMLFAAAALVSFGISAATAAQPQVVAAVAAGAPE
                     RLVVDKGPVTQAQTPLELLLFVHRADLPLRPLPSKQKDHS"
     gene            25939..27612
                     /locus_tag="P5537_07410"
     CDS             25939..27612
                     /locus_tag="P5537_07410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002928673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015114 - phosphate ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0035435 - phosphate ion transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi symporter"
                     /protein_id="HRV77908.1"
                     /translation="MDTSSLAIYPIVAGLLGGIGLFLLGMHMLTEGLKLAAGRALEGL
                     LERGTATPVRGLGAGMTMTALVQSSTAVTVASIGFVNTGLLSLQNAMWVIFGSNVGTT
                     LNAWLVAALGFSFRIDAFALPFVGIGATLMLAGRTVRQRALGQALAGFGVLFLGIDAL
                     KDTFSGFGAAMNLQDHIAPGLAGWLILVGIGTLLTVLMQASGAVIAIIITAAQGGLMS
                     IEAACAMVIGTNIGTTSTAILSALGATSNARRLAATHVIFNLVTGAVAIALLPLLISL
                     LGALRNWFEQPATPAVMLAMFHTAFNLLGVLLMVPLARPLRRYLAGHFRSREEEIARP
                     RYLDAPSLAVPDLALRTLRLELGRTQSFALTALTAATRVPPDEPWIERQASALDALAP
                     AIGDYVRKLNAMRLPPALVEAVAHSLRALQYQESAVTAVRQACALATTLGAPPGAELE
                     PVAAAFRQATGALAASADAAREDFSVAPVEVRLEEAELRYQAFKEALLLEGAHARIDI
                     RTMQDWLRLASLERRAIEQVAKAARMLAVLDGDLTPQQAAEKAGENGVE"
     gene            27802..28725
                     /locus_tag="P5537_07415"
     CDS             27802..28725
                     /locus_tag="P5537_07415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HRV77909.1"
                     /translation="MNAPNLSETAFSIAAVERDTGLAKDTLRVWERRYGFPSPTRDAN
                     GERLYPADQVEKLRMIRRLLDHGRRPARVVGASIEELSAMLDACLCPEGGAPAGRDDG
                     LLQLVRLHRSVELAAALRQALMKQGLQRFVAETVAPLAAAVGEAWMRGEVDVPEEHLF
                     TEQVQNVLRSAIGAHAASAGRPRVLLTTFPEEEHVLGLLMAEAMLVPEGASCLSLGTR
                     TPLADIRSAAVGGGFDIVGLSFSIAYPARQAIEGLLELRSLLPEGIELWAGGAAVRDK
                     QKRLPGIRVVGDLEDTMAALQEWRARNGAEG"
BASE COUNT         4982 a         9956 c         9716 g         4257 t
ORIGIN      
        1 ggtgccgtgc tggtcgtcgt ggaagaccgg gatcttcatg cgctcgcgca gcttggcctc
       61 gatgtagaag cactcgggcg ccttgatgtc ctcgaggttg atgccgccga aggtgggctc
      121 gagcgcggcg atcatgtcga tcagcttgtc ggcgtcgggc tcgtcgatct cgaggtcgaa
      181 gacgtcgatg ccggcgaact tcttgaacag cacgcccttg ccttccatga ccggcttggc
      241 ggcgagcggg ccgatgttgc ccaggccgag cacggcggtg ccgttggtga cgacgccgat
      301 caggttggaa cgcgcggtga gctcggccgc ctgcgccggg tcctcgacga tcgcgtcgca
      361 ggccgcggcc acgccgggcg agtaggccag cgacaggtcg cgctgattgg acagcacctt
      421 ggtgggcgtg accgagatct ttcccgggcg cggatagcgg tggtagtcga gggccgcact
      481 gcggatcagc tcgtccatgg tcttcctcct tggtcttttg cgtatgggac gggcgccgtg
      541 ccggcgcgcc gggcgtcaac ggcacaagca taccgcggac gcgcttattc tcgcattacg
      601 aaaacaaaat ttgcgatgtg aaaaatacgt ataccgaacc cacggcaacc ccttgcgata
      661 ggcggactgc atcacaccga tcgttacgat ccggttcatg gccgggggcc gggcatggca
      721 taattatggg ctcaaccgcg aacgatccgc cctgacggcg ctcgtagacg gaagtcggtg
      781 cgcccgcctc gggcgcccat gcagcccgcc ggccaggcag cccctgcagc aacgatggcc
      841 gaccgacggg aatggtttcg catcacagca cgggagagct gtacacatgt ctcagaacca
      901 cgcccaggcg gcgatcgccg ctgcccccga atacgtccgc cacgaaggcc tgaagaagtg
      961 ggtcggcgaa atcgccgcgc tcaccgagcc cgaccgcgtg gtctggtgcg acggctcgca
     1021 ggaggagtac gaccgcctgt gcgccgagat ggtcgaatcc ggcatgctga tcaagctgaa
     1081 cccggaaaag cgcaagaact ccttcctcgc ctggtccgac ccctccgacg tcgcgcgcgt
     1141 cgaggaccgc accttcatct gctcgcagaa gaaggaagac gccggcccga ccaacaactg
     1201 ggaagacccg gcggtgatgc gcgagacgct gaacggcctg ttcaagggtt gcatgcacgg
     1261 ccgcacgatg tacgtgatcc cgttctcgat gggtccgctc ggcagcccga tcgcccacat
     1321 cggcgtcgag atctccgaca gcccctacgt cgtcaccaac atgcgcatca tgacccgcat
     1381 gggccgtggc gcggtcgagg tgctcggcac cgacgccgag ttcgtgccct gcgtgcacac
     1441 cgtcggcgcc ccgctcgccc agggcgagaa ggacagccgc tggccgtgca acccgaccac
     1501 caagtacatc gtgcactacc ccgagacgcg cgagatctgg tcctacggct cgggctacgg
     1561 cggcaacgcc ctgctcggca agaagtgctt cgcgctgcgc atcgcctcga ccatggcgcg
     1621 tgacgagggc tggctggccg agcacatgct gatcctcggc gtcgagtcgc ccgaaggcga
     1681 gaagtcctac gtcgccgccg ccttcccgtc ggcctgcggc aagaccaact tcgccatgct
     1741 gatcccgccg aagtccttcg acggctggaa gatcaccacc gtcggcgacg acatcgcctg
     1801 gatcaagccc ggccccgacg gcaagttccg cgccatcaac cccgagttcg gctacttcgg
     1861 cgtcgccccc ggcacctcgg agaagaccaa cttcaacgcg atggccacgc tgaaggaaaa
     1921 catcatcttc accaacgtcg cgctgaccga cgacggcgac gtgtggtggg aaggcatgac
     1981 caaggaggcc ccggcccacc tggtcgactg gcagggcaag gactggaccc cggagatcgc
     2041 cagcgaaacc ggccgcaagg ccgcgcaccc gaacgcgcgc ttcaccgccc cggccagcca
     2101 gtgcccctcg gtcgacccgg cctgggaaga tcccgccggc gtgccgatct cggccttcat
     2161 cttcggcggc cgccgcgcca ccaccgtgcc gctggtgtac caggccttca actggaactt
     2221 cggcgtgtac atggcctcga cgctcggctc cgagaccacc gccgccgcct tcggcgcgca
     2281 gggcgtggtg cgccgtgatc cgttcgcgat gctgcccttc tgcggctacc acatgggcga
     2341 ctacttcaac cactggctgc gcatgggcca cgtggtcgag gacaccccca agatcttctg
     2401 cgtgaactgg ttccgcatga acgagcaggg ccagttcatg tggccgggct tcggcgacaa
     2461 catgcgcgtg ctcaagtgga tcgtcgatcg ctgcaagggc aagatcgccg ccaaggagac
     2521 cgcgctgggc tggatgccgc gcttcgagga tctcgactgg accggcgcgg aggtcaaccg
     2581 cgaggaattc gaggcgctca ccaaggtcga cgccgacgcc tggcgcgccg agctgaactc
     2641 gcacaaggag tggttcgaca agctgcagga ccgtctgccg cgccagctgg tgctcaagcg
     2701 cgagctgttc gaactggcgc tcaacgccga ctgaggccgc ctcgcgtagg agcgccggca
     2761 ggcgcgagcg tttcgtccga ctctggcttg gtcgcggaac gcaacgctgc attcgcggct
     2821 gccgccgctc ctacacgaaa accatcaccc cgtgagcatc ccacgtggag acttcgtcct
     2881 cgggcgagca tcccacgtgg aaccttcgtc gtcgggcgag caccacacgt ggaaacttcc
     2941 tcgccgtgga gcacctccat gtaggagcgc cggcaggcgc gaaccgggcg gtgccgcaga
     3001 cgacgaaccc cgccggagac caaaggccat cttcgcggcc gccagcgctc cagcatggac
     3061 acgcgaccga cgcaaaaagc gccccacggc gctttttgct ttttccgaac agcagaagat
     3121 cccaccatgc accgatcacg ccgcctcgac gacatccagc ccttccacgt catggagttg
     3181 ctgcgccgcg cgcgcgagct cgaggcgcag gggcgcgaca tcatccacat ggaggtcggc
     3241 gagcccgact tcggcacccc ggcgccggtg gtcgaggccg ccaaccgctt cctcgccggc
     3301 ggcgacgtgc attacacccc cgcgctcggc ctgccggcgc tgcgcgaggc gatcgcgcgc
     3361 ttctaccacg accgcttcgg tgctgacgtc gcccccgagc gcatcgtcgt caccgccggc
     3421 gcctcgggcg cgctgatgct ggcgctcgcc gccaccaccg acccgggcga cgagtggctg
     3481 ctgcccgacc ccggctatcc gtccaaccgc cacctgatcc gggccttcga aggagtcgcg
     3541 cgcgcgctcg aagtcgatgc ggcgagccgc taccagcccc ggcccggaca ggtcgacgca
     3601 gcctggggcg agcgcacccg cgggctcatg gtggcgacgc cgtccaaccc taccggcacc
     3661 ctgctgtcgg tcgccgagat cgccgcgctg caccgcagca cgcgcgcgcg cggcggcgtg
     3721 ctgctggtcg acgagatcta ccaggggctg acctacggcg tggaatcggc caccgcgctc
     3781 gccgacccgg tgctgaacgc ggccgacgac gtcttcgtgg tgaatagctt ctcgaagtac
     3841 ttcggcatga ccggctggcg gctcggctgg ctggtggcgc caacgggctt cgtgcgcgag
     3901 ctggagaagc tcgcccagca tttcttcatt tcgccctcga cgccggcgca gcacgccgcg
     3961 ctcgccgcct tcgcaccggc gacgatcgcg atcctggagg agcggcgcca tgagttcgcc
     4021 cagcgccgtg acgtgctgct gccggcgctg cgtgagctcg gcttcggcat cgccaccgag
     4081 ccgcagggcg cgttctacgt gtatgcggac gtgtcggcgc tggccgacga ctcggaagcg
     4141 ctcgcgcgcc ggatgatcga ggaagccggc gtggccgcca cgcccgggct ggacttcggc
     4201 caccacctgc cgcggcgcca cctgcgcatc gcctacacca cgcgcagcga gaggctgctc
     4261 gaggcggcgg accggatccg cgcgctcggg ctggggcgct gagcgggcgc ccggctggag
     4321 tgccggagcg gtcgatggct cgggggctcg ggatctcgcg cgccggagcc tgggcagccg
     4381 aattcgcggc tgccgccgct cctacagggg acggaacggc gacgatttct gtaggagcgc
     4441 cggcaggcgc gaatgcggcg gaatagccgc tccaaggcat ggcctgcgcc ccacccgggc
     4501 tcaggcaccg catccaccgc gaccaaggcc cgcgggggag cgggttcctg ccgaagctca
     4561 gctcgcctgc tcggcgtcgc gaccgctgtc gcggccggcg atcagcatca ggcgtttttt
     4621 cagcgccatc accttgcggg gataacgcgc cttcgggtcc ttgagcgagc cgttgtagta
     4681 ctgcagcgca cgctgcatgc tgccgtagcg ctccaggccc tcctgcagca ccagggtgcc
     4741 gacgcggaca ttggtctcgg ggtcgaagag gacgttgcgg ccgcgattgg ggccgatctt
     4801 gtccttgtgg tagcgcggga tcacctgcat cagcccgagc gcgcccatgt tgctgaccgc
     4861 gcggtggttg aagctcgact ccaccgccat gatcgcgacg atcagcagcg gatcgaagcc
     4921 gagctcctcg gcgtgcgtct cggccgcagc cagcgcgggc tcgatcgcct cctcggagac
     4981 gcgataggta tcggcgatcc agtcgcgcac tcgcgccatc tcgtccgaga gcgcgccctc
     5041 ttcttcctcg aaggggttgt ccacgagcgc ggcgatgtcg cgcagcgccg gctggtggaa
     5101 caccggcggg accggctccg ccacgacacg ggcgagattg cgctcgacca gccccggcgc
     5161 agccaccggc aggctttcgt gcaggcgcgt cgaggccgcc agcgaaggta cggccgccgc
     5221 gaaggacggc gcgacctctt caacccggcg cggcgcgaag gaaagcaccg aggccatggc
     5281 cagttcggac gcggtgggct cggcctgctg gctgaggacg tcgccgtagc gcacatccgt
     5341 tacgccaccg ctctgtgtgc cgagccagcc catgcccatg agacttacgg aaagaaccgc
     5401 accgtgcgcc agactgcgcg cagcgccgcc cgcttgacgc gcgagcgcct tgaatcgagt
     5461 tgcgtgtttc atggtgtcct ccatgctgtg gcctgagccc tgccgtggac gagccctgtg
     5521 gtgggggccg cccggcgccg ccctgtgggg cagcgtccgc gtcgctcggc gggtaggccg
     5581 gcacgacggg caggagtact cggtcgccag taggtgttaa gacccttcgc cgcaaccaga
     5641 cgacgggccc cgcggtgcgt gcgtccatga aactgcgtct caccttgcgg gaggcgccgc
     5701 accgagatcg gattgggaat gttgcgatgc aacaggaaac ggattgtatt cgctcacagg
     5761 tttattgtca aaacctgaca gccccgtcgc aacagcaaga aacacttgaa ttcacgggaa
     5821 gttttgaccg atcagcagct tgcgcggcgc tgtttgcaca tcacatcaag gcgcttccag
     5881 tcgaaaaaag gccccggatc ggtcttgcgg ccaggcgcga tgtcggaatg cccgaccacc
     5941 gcctcgatcg gatagcgtcg ctccagctcg acgatcagcg ccgccaggcg ctcgtactgc
     6001 gcgggctcga agggcatcgt gtcgcagccc tcgagctcga tgccgatgga aaaatcgttg
     6061 cagcgctcgc gtccgttcca gcacgacaca ccggcatgcc aggcgcggcg agcggggtcg
     6121 acgaagcaca gcagctggcc gtcgcggcgg atgaagtagt gggcggagac gcgcaggtgc
     6181 tggatggtcg cgtagtaggg gtgtgcggtg gggtcgaggg tgttggtgaa gagctgctcg
     6241 acaccggggc cgccgaactg atcggggggg aggctgatgg cgtggatgac gatcaggcgg
     6301 acgggctcgc ccgcggggcg ctcgtcgtgg ttgggggaca gcggggtcag gtctttcatt
     6361 tactcatttg ctcgcttgca ttcccggcgc cgggaggctg gcgcgccttc cggtccttgg
     6421 cgacgatccg gctgatcgaa ctgtagtgga ggccgaagaa ctgggcgagc tgcgcgaggg
     6481 tgaaggcacc ggaggccgcg gcctcggcga tggccgcatc gcgcgacgca ctgcgctcca
     6541 catacgcctg caaggacatg ccctgcggcc ggcgctgcag ccgcggcact tcgtcgaggc
     6601 gcccgtcgtc cggcaccttg tgcgccatct cgtcggcgaa tgccccgctg cccagataga
     6661 tctgcgcatt gaggcgttcc cagatcggcg gcaggccgac gcccgcgcgg acgaagtctt
     6721 cgtatcgacg cacggcagcc gtccgctccg agccgaactg ccccagcacc cagtccgtct
     6781 ccagccagga cggcggatcg accagcccca tcagtgcgcg atggctactc cagggccact
     6841 cgcgcgcatc gccacagagc cccgcccgca cggggttgag caccacatag cgcgcgagct
     6901 ccacgaggta ggcgtcggct tcgaccagga tcgccttgta gcgcccctgg aagacgtgcc
     6961 cgacacgagc gtggcgtcga ttcgcggcct gggtgtacac cccgttcagc tgtctcatgc
     7021 cccgggagag gttcgcctcg gcggtctcca cgaccaggtg gtagtggttg cccatctggc
     7081 accacgcgtg acaacgccag ttgaatcgat cgcagacctc gccgaagagt tccagccaca
     7141 acaggcgatc gacgtcgtcg gcatagatcg gctcgcgacg gtcaccacgc gaagtcaggt
     7201 ggtacacccc tccggcaagc tcgatccgca atggccgcgc catgatcctc tcccagggca
     7261 ggaacagccc tgattatccc gaatggataa tcgaaaaggc aaggccaaag gaagagcact
     7321 cggccacggc ggaggcgaat gagcaaatga aagacctgac cctaggggtc ccctacgcct
     7381 acggccggaa cacctctatg cagagctgct ccacatggcg atagtgacga tcgtttgccg
     7441 tcagcagatc gagcccgcgc tcgagcgccg ttgctgcaat caaggcatcc gccatctgca
     7501 tggaatggga aagcgcgaat tgctcgcaaa ggaagcatgc acgcgcggag atggcctcat
     7561 cgacctgtac caccctcgcc gaccagaagc tcagggcctg ccgaagggcg cgcaactccg
     7621 acttgtcacg cactccctgg acaagctcca tgtacgtcac cgccgacacc agaaaccctg
     7681 gcatcgcatc cagccgatcc gctgcacgcg cgttgcctcg caggttccag atcagcacgt
     7741 ccgtctccac gagcatcacg gcagcactct cggctgtcgc agcctgcgca cgtcatcgtc
     7801 taccgtgccc tgccgatccg cccacagacc aaacgcagga ttgcgctcgg catgcgcccg
     7861 ggcacgggtc tcttcgcacc gcatcaacac cgcccgtgcc tgcccccggc tggtgatggt
     7921 cacccgctca ccacgatccg ctgccgcaag cacctctgcc gtgtgcaggc gcaaatccct
     7981 gatggtcgct tccatgacga gctccgtttc acaaacgcgt gaacattaca tcatgaaggc
     8041 actgaagaga gccagatgag caaacgaacg cccggccccg agccctactt caccgtatcc
     8101 acaaaaccga tgctggcctg gggcgcactg ttgatcacat cccagctcac ggtcgccgcg
     8161 ccgttctcga acgtgcgccc aacgccgaca tcgagcccga cacggttcat catggggtaa
     8221 tagctcgccc cgacggacgc cacggtgcgg tcctcacgat cgctcgacag caccttgacc
     8281 gacagacccg gcccgccgcc accaaagttg tagttgatgc cgaacatcac ggcagggtcg
     8341 gcctgcgccg tcgtggcggc aagcgcaagg atcgagacgg tgagcagttt ctgcatgagt
     8401 ttcatctccg gatcggttct cggcaaagct gcgcaggatg cgcacccgct ggagtgacca
     8461 cggtgacgaa gaaaaattgg ccacgacgcc gcaccggata cccaggcggc cgcccacact
     8521 ctatttccgc cacttgacaa aataaggaaa attccttact ttcagcctca atatcgattc
     8581 cccggaggct caccatgccg gcaattcacg aagtcgcaac catcacatcc aaaggtcaga
     8641 tcacgctacc caagcccatt cgtcaggccc tgggggtgga tgttggaggc aaggtcgcct
     8701 tcgacctcac cggcgaccga gtgatcgtga cgcgcgcaac cgaaatcgcg cacgaggatc
     8761 ccgcaatcgg cagcttcctc gctattctcg aagaagatat ccggtccggc cggcacatca
     8821 cgacgctacc cgacgatctg acgcgctcga tgctcgctgc gctcggcaaa cacgcggatc
     8881 tgcgcgaaga catcgaaggc gacgtcgcgc tgtgatccag cgtcacggat ggaatctgct
     8941 cttccacgat tgcctgatcg cgcagctcca gaaactggat gccgctgccg cgcgcgtgcg
     9001 ggcgcaggat ccagagcgct acgaatccaa cgcaaacacc aagctgtttg ccgcgctggc
     9061 gaatttgatc ttcgagaccg ttccaggcga tccgaacagg gaagaatacc gacaaggcaa
     9121 taccatgggg ccggggttca ggcactggcg ccgcgccaag atcggccggc gctttcggtt
     9181 gttctttcgc ttcgactcca agaccagaat catcatcttt gcctgggtga acgacgagaa
     9241 aaccttacgc tcgacaggtg ccaaaactga cccttatgcg gtctttcaga agatgctcaa
     9301 gtcgggccac ccacctgatg actgggacgc gttgctgaag gccagcaagt ctgactggaa
     9361 ggcataaggc tgcgcgcgcc cggcagatta ggaaggtggc ggcgtaaaac gcgaaatcgt
     9421 ggcctgtccc cgacttccgt tgcgcaccag gcgctcggac cgcggggagc ccatcaaccc
     9481 gcgcagctcg agcacatcgg ggaaggatgc gcacggggtg ttccttccga ggctgcggaa
     9541 ctcgccctgc gggctcggac agtcctcgcc tctccaggaa caccccgcac gcatccggga
     9601 accgtgggcg catcacgacg gaaaagtgga actcgatggg ggcgaagcag gcgcaccgcg
     9661 aaatgcttcc tgccccctgc ctgcagcact cacctaactg cggagaaggg gcgacgcact
     9721 ctgtcgcacg ccaagggccg ccccgccaca atcaccgtag cccgggatgt tgggcattcc
     9781 tggcgcaggc gaggactgtc cgagcgaagc gagttccgca gcctgcagaa ggaatgcccc
     9841 gcgcgtcccc ggcggattac gagcacagcg ggaaaaagac acaagggtgg gaaatcgtgg
     9901 tctgcccccc atttcccatc acgaagccac cgacgggagg gaaatgagca aatgaaagac
     9961 ctgaccccga ggaacccctc accccgcccg ggcggcctgc ctgatcgcct cggctgccca
    10021 ctggttcaag ctctgcccgt gcgcagcggc agcgacgacc gccgcctcgt gcaccgcggg
    10081 atcgacgcgc agcgagaact tgcccgagaa acgcttgcgt ggctcgatgc cccgccgttc
    10141 gcacgcatcc aggaacacgc ggagggacac atcaccttcg cgcctcagtc cggccacatc
    10201 cgccgcataa aaatctgcac caccattcaa accgacgaac tcgccgcgaa acatctggat
    10261 gtccggatcg aaggtgatca cggcctcgta gcccccgatg ttcatggtgt tcatggttgc
    10321 actccgttgt cttcaagcca cttccgaatt gctgcgactg cgcccttgtc ggtatccggg
    10381 gacgggtgcg ggcgatgaaa gatacgcacc acaccgaaca ggaacacctc cacccgagaa
    10441 ccttcgcgct ccgaaatctc ggcccccaac tcccggaaca aagcctcgat atccccccag
    10501 cgcacattgg ccgagaccgg ccgggcatgg atcagttcaa gggtgcgctg gtgtttgcgt
    10561 ttcacgacgt tatggtatca aaaaacgata tcagacgaaa ataagcaaat gaaagacctg
    10621 accctagagc ctctcccttg aaccatcgcg gttcgggtgg gatgcaggca ctgcggaggc
    10681 tgcggacccg gcggctacga tacctgaccc cagggctccc tcagagcatc tggccagctc
    10741 gaaatcgaaa tcgtggtctg tccccgattt cccgctgcgt ccgacaacat ccctgaagat
    10801 ccgcgcctgc tggcgctccc agaagggcat cgcggttcgg gtgggatgca ggagctgcgg
    10861 aagctgcgga cccggcgacc acgatgccta accccagggc tccctctgcg catctgacca
    10921 gctcgaaatc gaaatcgtgg tctgtccccg atttcctttc cgtccccgat ttccacttcg
    10981 ttcgctgtga tcaacttacg gcgagacttg cacccgcagg agtgcgccca tgctgggcgc
    11041 acacgaaaaa acgggagccg aagctcccgt ttttaatttc aaacctgtct aggagacaga
    11101 ttagaaggtg tggcgaatac ccaccgcgaa gacgctggag tcgtcgccgt tggcagtgcc
    11161 agccaccgga ccgaaagcca tggtgccgct ttcgttctcg gtctggttgt aggcggcgta
    11221 ggcggtcgta cgcttcgaca gggcatgggt gtaagccagc gaccagcttt ccgcgccaag
    11281 attgctcttg tcgtcgcgat caaattcgcc gtaagcgagg tggacattac cagccgcgct
    11341 aaccggaacg atgacaccga tctgccacag atcagcctcc gcacccttcg caaacttcag
    11401 gccttcagca gcctgatacg agccggcgac cttgaccata ccgaagtcat agctaccgcc
    11461 gatgccccat tcttcctggt cttcagcgcc atcggtgaag agatactgat aaacagcacc
    11521 cacagccagc gggccgttcg cgtagtcgac gctcaggccg aaggcatcgt cgtcttccgg
    11581 attcagcgag gtttcaacag ccttcatcga gtagatcgca cgagcggtca gacccgagaa
    11641 cgaacccgtg taggcgaccg agttgtccca gcgagcgggg ctgttcgggg tgatcgtcat
    11701 gcccccggcg gccgacagca acgactgggg accaacggac gcgccgagaa cagcgtcgta
    11761 gttgaagaaa tagccaggag cgtattgacg accaacgctc acggtaccga aggaaccgct
    11821 cagaccgacg taggcttggc gcgaaaagac cgaatcgccg tccacaatcg ttttgccgtc
    11881 agtatccgtc gccttttcat tcgaaccaac ggcaggcgaa gccacgccat taccgatatc
    11941 gaagccttgc tcgagggcga acacggcctt gaggccgtta cccagatcct cggtaccgcg
    12001 gaagccgata cgcgaacccg acagcacgcc gttgatgacg ccgttgaagt cgttcttgcc
    12061 gtgctcacca agaccgatag cagcgtcagc cacaccgtaa atggtcacgt tcgactgagc
    12121 gaaggccgga gccgaaacca ggccagcaac agccagcgcg atcagtttct tttgcatatg
    12181 tttctcctca aatttgaagt tgagaccttg gcacctgcct tggccctact cacctctctg
    12241 gcgagaagtt ggagcgattc tgcaaacctg ccgccggcct tgcaagcatg acaacgcgaa
    12301 aacgcgacat tccgggcttt ggtgttgcgg acgtgcaaca gaacgcctga tcagcgccgc
    12361 gcatcgagcc gcggcagacc cgcattccat gccaacagct tctcgtccgc cgtcaccagt
    12421 gtcgcgttgc gcacgcctgc ggtggcagcg atgaagcggt ctgccgggtc gcgatgcaga
    12481 tccgcgaacc ctgccgctgc cagcacgatg cgcccatcga gcgcgatctc ggccagcccc
    12541 gcgcccagca ggcctgcccg ccagctttcg acagcaagcg gcaggacgat gcgccccttg
    12601 tccgcaagca ttgcgcattc ccagaagctg atcgcgctca ccgcgacctc gcccgcgcgc
    12661 caggcctgct cgatgcacgc acgcgcctgc gggccgagcg cggaatcgtc ggcatccatc
    12721 cagatgagca catgcgtgtc gaggacgatc acgacaaggc ctcccagtcc tcgtcggcga
    12781 ccggcgacac gatgtcgccc aggatgcgca cgcccgggtg cagcccgaaa ggcgacgata
    12841 cacgcgcgcc ctgataagga tgcagctcgg caaccggctt gccgttcttc gtgacgacaa
    12901 ggatctcgcc cgaggccgcc acctggtcca tcagggcgag gcagcgagcc ttgaattcgg
    12961 aggcctggat ggtttgcatg ggcgtactcc ctggatagtc gatgaccatg atcatgacca
    13021 tggttgcaca tgagatcaag cccaatccac catcccagac acagacgctt gccgcgccgc
    13081 ctaaagtagc tactatggat ctatctcgac cctactcagg acactgatca tgaaagtcat
    13141 gaccgcacgc gaagcaaaga accggttcgg cgaattcctc gatgcatcgc gccgggagcc
    13201 ggtcgtcatc accaagaacg atcgccccgt cggcatcatg gtgtcgatcg aggacgcagc
    13261 agacacgctg ttgcccgaat tcctgctcga caagacaccc ggttacgacg gctggctatt
    13321 cgagaaggtc acggcgacgc tcgagcgcct ggatgcgggc caaaccacgc tacatgccca
    13381 cgacgaagcc atggcgctgc tacgcgagcg tgtggcagca cggaatcgcc gtgcatgaac
    13441 atcctctgga ctgacgaggc gctggacgac cttgaggaga tccttgttta ttaccactcg
    13501 gaggcaggcc ccctgactgc cgaagccgtc cattcgcgca tcgttgccga gatcgaagcc
    13561 ttgcgcgtct tccccgagcg tattcgggca agtacgcgaa tcccgggggc acgtgagctc
    13621 gtcgttcgcc gactgcccta tgttgccttc gtgaaagtga cggatgacgc ggtgatcgtg
    13681 ctcaacgtgg ttcataccgc acgggagttt ccgtcgcggc gctgacgtgc ttggccaagc
    13741 ccgccggcag cacgcccgca gctcggcaat tgcgtacatt ttgtacaaaa catacagtcc
    13801 aatctcacca aaacgaacag gagtcgccac catgcgcacc gtctccgcca ccgaggcaaa
    13861 acaaggactg gctggcgtac tcgacctggc cgcacatgaa cccgtcgtga tccgccgcca
    13921 gaagcgcgat gtcgcggtcg ttctgtcgat gaaggagtac gagcgcctca cgcggctcaa
    13981 cgtcgccgag ttccagcgct tttgcgacgc agtcggcgag aaagccgcag cggcgggact
    14041 gaccgaggac aaagtcgccg aattgctcgc cgatgactga attcctgcgc ttcgtcgtcg
    14101 acacgaacgt actcgtcagc cgccttttgg cgccgcgcag caccgccgcc aaggcggtcg
    14161 accgggcgct cgcccaaggc aacctgctcg gctcggaaga aaccctggcc gagctcgtcg
    14221 aggtgctggc acggcccaag ttcgacccgt atgtatctcg agaaggccgg cgcgagttca
    14281 tccgtctgct cggcggcgtc atgcaggtcg tgccgatcat tcgcagggtg gcggcctgcc
    14341 gcgatccgcg cgacgacaaa ttcctggatg tggcgcttgc aggcgaagcg gcggcgatca
    14401 tcagtgaaga caaggatctg cttgtgctga acccatggca cggcattgcc atcctgacgc
    14461 cagcagcgtt catcgtgcgt tgaatgaaga gggcagcgca gaaggcaggt cagcttacgg
    14521 gttcgaggcg cagcccgccc acgggaaaca agtggatatt tgccctgttg ctacgcgagc
    14581 actaaaatac acacgccagc gtatttacaa gaggtgatgc catggaaaca ctgcccagcc
    14641 gcgtcttcaa caacggcaac agccaggcgg tccgtattcc ggcggagttc cgcctcgaca
    14701 ccgaccgcgt cagcatcacg cgcaacgacg cgggcgacct ggtgatccac cccttgcgcg
    14761 tgcagcgtgg caccgccctg atgcaggccc tgaaagcgct gggcgaagtg gacgacgact
    14821 tcgtcgccgc gctcgaggcc gagcaggaaa cgccgctgcc ggtgcaggag cgcgaggcgc
    14881 tgtgatctac ctgctcgaca ccaatatcct gatctacctg atcaagaacc agccgcccgg
    14941 catcgcgcag cgcatcgaca cactccccga gagcgacacc ctgtgcatgt ctttggtgac
    15001 ctgggccgag ctgctgaagg gcgccgagcg cagcactcgc aagacagagg tgctgcggcg
    15061 gctgaacgcc ctggcacgcg aggtaccggt gcgctatccc accgcccccg ccatctgccg
    15121 gcattacgcg gaacaggcca tccgcctgaa ggaggcaggc acgccgatcg gcgcgaacaa
    15181 cctgtggatc gcctgccatg cgctggccga agacgccacc ctggtcaccc acaatacgcg
    15241 cgagttcagg cgcattgcgg gtttgcgcgt cgaggactgg gtgtccgccg aaaaagactg
    15301 aagaaggctg cccccggaac tcccgccgcc ccttagcact ctcacgccgc gagtgctaac
    15361 attcaagcgc acaaggagga ccccagccca tgtcacaagc cctgaccttc cccgttcccg
    15421 ccgccggcag cctggaccag tacatccaga gcgtgaatcg catgcccatg ctcagcgagc
    15481 agcaggaggt ggagctggcg acgcgcttgc gtgacgacgg cgacgtggat gcggcacggc
    15541 aactggtgat gtcgcacctg cgcgtcgtgg tggcgattgc gcgcggctat ctcggctacg
    15601 gcctgcccca cgccgacctc atccaggaag gcaacatcgg cctgatgaag gcggtcaagc
    15661 gcttcgaccc cacgcgcggc gtgcgcctgg tgtcgttcgc gatccactgg atcaaggccg
    15721 agatccacga gtacatcctg aagaactggc gcctggtgaa gatcgccacc accaaggcgc
    15781 agcgcaagct gttcttcaac ctgcgcggca tgaagcagga cagcagcacg ctgcagcccg
    15841 ccgaggtgcg ctcgatcgcc gcgcagctgg gcgtgaagcc cgaggaggtc gtcgagatgg
    15901 agacgcgcct caccggccgc gacatcccgc tcgacgccgg cagcgacgac gaagacgagc
    15961 gcttcgcgcc catcgcctac ctgcccgacc cgcacgccga gccctccgag cagatcgagc
    16021 aggcccagct cgcccgcctg caggacagcg gcctgcgcga cgcgctcgcc agcctggacg
    16081 aacgcagccg cgcgatcgtg cagcggcgct ggctcgccga gggcgacagc gccacgctgc
    16141 acgagctcgc ggccgagtac ggcgtgtcgg ccgagcgcat ccgccagatc gaggccaagg
    16201 cgatgcagaa gatgcggggg atgctggcgg cggtggcgtg actgctgaca gcccccacga
    16261 aatgcaaacg gcggtccagg accgccgttt gcatctggag tgcgcgttgc gcgcgctcgt
    16321 ctcacttccc cgccagcagc gccttgatgt ccgccaccac cacctgcggg tcctcggcgt
    16381 gcttgacgta cagccgcggg cggccgtccg ggccgaagac gtaggttccc gcggtgtggt
    16441 cgatggtgta gtggccggcg aggtcgccgc tcttgcggta gaagacgcgg aactccttcg
    16501 ccacctcggc gatcttctcg gccgtgccgt acaggccgag gaagcgcgcg tcgaacaccg
    16561 gcacgtactg cgcgagcagc tcgggcgtgt cgcgctcggg gtcgacggtg acgaagagca
    16621 cctgcacgcg atcggcctcg gggccgagct cctgcatcac cgtgctcatg cccgacagcg
    16681 ccgtcgggca cacgtccggg cattgcgtat aaccgaagaa gatcgtgacc accttgccct
    16741 tgaagtcggc gagcgtgcgc tcctggccgt ggtggtcggt gaggcgcagc gtcttgccgt
    16801 agctcgtgcc ggagatgtcg gtgctcttga atacgggctc ggcgggcgtg cagccggcaa
    16861 gcaggccgag cgcgagcagc ggggtggcga cgaggaggga gatcgcttta cgacgtgaag
    16921 acatggggct tacctgtgtt tcgattccat aagcacccga tgatagtccg cttgcccggc
    16981 tcgggtcagc cggatgtgcg acggagcgcc tcatcgatct tgggggaaca cccgcgacgc
    17041 cacgccaggc ttcgccgctg gtcgcacgtt catcgaggcg ggtcggtggc acgcaagcgc
    17101 cgcctgaccg cgcgcatcag ccccccgagc agcggcagct tctcgtacag ttcctcggcg
    17161 gcgtcccagt agtcgcggtg cagcgtcacc cggtcatcgg cgtcgaagcg caggtgcgtg
    17221 acgccgcgca ccgtcagcgc gcgcccgcgc agcgcgaagt ggaacgtcca gcccagcatg
    17281 gcctgcccgc cctgctcgat gcagtcggtg acctcgaagc gcggcgcctc ggtggtggcg
    17341 aacatgtgct cgaagatgcg gcggatggcg gcggtgccgg cgacctcgtt gaaggggtcc
    17401 ttgaagcggg cgtcgggggc gtagaactgg tcgaggccgt ccagcgcggc gggggtgagc
    17461 gtctcgtaga agcacgccag gcgcagggcg ggcgattgcc gcacgggctc cggcgtcgag
    17521 gcggctgctg gcaggggctc cggaagcttc gggtcggtca tggcggcaag cctacacgcc
    17581 ggtggcgcgg cggatcagcg cgaaatagaa gcggcgcggc agcaactgca ggaacttcag
    17641 cacgcgcgtg aagcgcttcg ggaagtggat ctcgaagtcg ccgcgcgcaa agccgtcgac
    17701 gatcgcatcg gccgcctgcg ccggagtctg cagcgcgggc atggcgaagt cgttctgcgc
    17761 ggtgagcggg gtggcgacga agccgggatc gatcaggaac acgccgatgc cgcgcggcga
    17821 caggtcgagg tggaggactt cggcgaagtt gatcagcgcc gccttggagg ggccgtacgc
    17881 cgtcgccttg ggcagcccgc cgtagccggc aacgctgccc accagggcga tcgcgccctc
    17941 gccttgcgcg agcagggtcg gcagcacggc cgccgtgccg ctcatggtgc cgacgaggtt
    18001 ggtctccagg gtctcgcgca cggcctgcgc gctcagctcc caggcacgca gcgggcggta
    18061 ggtgccggcg ttgaagacga cgaggtcgat gccgccccag tcggcgagca gctggtcgcg
    18121 cgcgcgctcg agctcgtccg cgcgggagag gtcgagcgcc agcgcgcgcg cggcagcggg
    18181 cgaaccggcg cggcgcgcgg gctcgacggc cgcgttcgcg ggcgagcccg cgttcccggt
    18241 ggccggcgcg gcgccgccga ccggaccggc gccggcggcc gcatcgcagg ccgcgcacac
    18301 cgcctcgagg cgttcccgtc cgcgcgcgga cagcgccagg cacgcgccgc gacgcgcgag
    18361 ctcgagcgcg agcgcctcgc cgatgccgga cgacgcgccc acgatccaca cccgccgccc
    18421 cgcccactcg cggatcggcg tgttcagcgg cgcgaaccag ccgcggcggg cggcaggcgc
    18481 ggtcacggac gcgccctctt gtggaaggac agcgtgacct cgccgaggcg aaagccccac
    18541 ttgctcatca gcgagcggtt gagcatgacc tggtcgtcca tcaggaacat ccagtcgtcg
    18601 aagtcgacgt tgtagacctt gccatccacc ggcagcgcca gcacgtagcg ccagcgcagc
    18661 gcattgccgg ccgcctcgcc ggttgcctcg ccgaccacgt cgtcggcacg gccgctgtag
    18721 cgccccggcc cgagccgcgt gatggtccac acccgacgct gggtcgtgcc gtcggagtag
    18781 gtgaaatgct cgtctagcgt gccggtgtcg ccctgccagc gtgcgtcgat gagcacgtgg
    18841 aagcgcttga ccaccttgcc cgagcgatcc tggaacatgc cccaggcgtc gatcgtgccg
    18901 tcgaagtagt cgcgcagctc gagcacgggc gtctcggcac ggtaatcatc gatgttcacg
    18961 ctgctgcacc cccagagccc cagcagggca acgcacatca ggaaaaaacg tttcacgatt
    19021 gctctccacg aagatccttc cctcccacgc ctcctgggac cggactcgcc cgccaccctc
    19081 ccggctcgat cgcatcccgc cagcgccaca gcagcgcgat cgccgcgagc ttgagcgcga
    19141 ccggcacgaa gccgtacacc gccgcgagcg cgccgactgc cgcggcctcg cgcgcgcccg
    19201 gcgtatagcc gagcagcgcg agcagcggca gggcgaggcc ggcggcgagc gccaggttgg
    19261 ccttggtgac gaagctccac cagccgaagc aggcgcccgc ctcgagcgtg ggcgcacagg
    19321 ccgctccgtc gtgcatgcgc gcgtcacccg tcatgccgat cggggccacg gcctccaagt
    19381 gccgagaggg cgcccgctcg cgcccacgcg cgagcaggtc ggcgagcagc gagggcggca
    19441 gggtgaggtc ggcgcccagc gccaggcccg agagcacgca gatgcaggcg taggcgacca
    19501 ggtcgccgct gccgagcagg cctgcccagg cgaacaccgc caccgccagc gccatgctgc
    19561 cgagccaggc gcgcagcttg ccgatgcgct gcgacagccg cgtccaaacg ggcagacccg
    19621 ccgctgcggc gacaaagtag agcgcgagga aggcgccggc gagcgcctcg gcctgcagca
    19681 cgtcggcgac gaagaagagc accgtggccg aagggatcgc cgcggcgatg ccgttggccg
    19741 cgaacaccgc gagcaggcgg gcgaagccgg cgtcgccgag cgccgcgcgc aggccccgcc
    19801 acagcgcagc gcgcaccggc gcgagcggcg gcggcgccgg cgcgcgccac agcgtccaca
    19861 ggccgaagac cacgagcagc ggcaggaaag cccaggcgag ccgcgccagc ccggccgcgc
    19921 cgccatcgct cacgctggcc ggggcgccat cggccggctg cgcggaaacc tccgcctcgc
    19981 ggaccacccc ggctccagcg ccagccccct ctccccccat cccagcgtca ccgagcagcc
    20041 ccggcagcgc cgccgccagc accacgccgg cgagcgcgaa ggcctcgcgg ctggcgacga
    20101 agcgggtgcg cgccgccggc gtggcggcca cctcggcgcc ccaggcgttg taggcgatgc
    20161 tcgccaccga gtaggccagc gacaccgcca ccagcaggcc gaacagccac gccgccccgc
    20221 tccccgcggg cgggaccagc aggccgagca tgccggcgcc gagcgcgggc agcgccagcg
    20281 cgatccacag ccggcgccgc ggcaggcggt cgttggccca gccgatgagc ggatcggtca
    20341 ccgcatccac gatgcgcgcg gcgagcagga ccgcgcccac aagcgcgagc gaaaggccca
    20401 ggccctcggc gtacaggcgc ggcacgtgca cgtagatcgg cagcgccgca aaggccagcg
    20461 gcaatccgag cgcgccgtag gcgatcagat cgccgcgctc gccgcagccg cgagcgcgac
    20521 cgatgccgga tgcgccgggc gtgccagcgc tcgcgtcgcc agcggcgcag ccgtccggta
    20581 cgacgcgcgc gccctcggtc atctcgcccc gtccgccaac ccgagcaggc gcgcccgcag
    20641 ggcgggctcg cgcgtgcgct cgtcgagcca gatcgcgaag aaggcctgcg ccagggccgg
    20701 gtcgtcgagc tcggcggtgg ggcgtccgtc gtgccagaag gctgcgcccc ggccggggcg
    20761 gtgcaggccg gtgagggtgt cgccggcggc gaccgcaggc agcgccgcgg cgagcgcccc
    20821 ggcccagcgc gccagcgtcg gctcgtcagc gaggccgagg cggcgcatct cgtcgaggct
    20881 gagctcgacc aggcgctcgg aggtgaccgc gcgcgcatag cggatggaga gcacgtactc
    20941 gtcgtccatc gcctgcgcgc ccggtgcacg cgcccacaac gcggcgtcgt agagcttgaa
    21001 gccgagccag cgcagctcgc cgcggccgat ctcgcgcagc ccggcctcgc tcgccgcgag
    21061 ctgcggcggc aggccaagcg cgtgcaccgt ctccatggcg agcagcatgc agcaggcgag
    21121 cacgacgccg agctcgcgcg ccttgcgggc gcgcggcgcg cggacgagcc ggctcaggcc
    21181 gcgcctcagg cgttgcgggg cgcgcgcggg aaagcgggtc ggtgcgttca tgggctcagc
    21241 tccaggttca ggatcaagcg gcaggcagcg tcgatcgcgg ccgcgccggc cgcgatgctt
    21301 cagccggctc gcgaggccgc cccggcatgc gcgaacacat agtggtgcac gtcgatgtcg
    21361 ccggtgtcga agcccgcctc gcagtacgca agataaaaac gccacatgcg caggaagcgc
    21421 tcggggaagc cctgggcgcg caccgccgcc gcctgcgcgt cgaagctgcg gtgccagtgc
    21481 gccagcgtgc gcgcgtagtc gcgcccgaag gcgaagtcgc ccaccacctc gagcccggcg
    21541 cgcccggcct gctgcgcgac cgcgcccggg ctgggcagca tgccgccggg gaagacgtgg
    21601 cgctggatga agtcggtgcc gcggcggtag cgtgcgaaca gcgcgtcggc gatcgtgatc
    21661 gcctgcacca cgcagcgccc gcccggtttc agcaagcccg agagctgggc gaagtaggtc
    21721 ggccagaagc gctcgcccac cgcctcgatc atctcgatgg agacgatgtg gtcgtactgg
    21781 ccgcgaacgt cgcggtagtc gcacagctcg aagtccaccc ggtcggcaaa gccgccgcgc
    21841 tcggcgcgcg cgcgcgcgaa ctcgagctgc gagggcgaca gggtgatgcc gagcaccttg
    21901 cagccgaact cggtggcggc cacctcggcg aagccgcccc agccgcagcc gacctccagg
    21961 atggtctgcc ccggctgcac gccgagctcg ccgaggatgc ggcggtactt gcgcagctgg
    22021 gcgtgcgcca gcgactcgtc cggcgaggcg aacaccgccg ccgagtaggt catggtgggg
    22081 tcgagccaga gggcgtagaa gtcgttgccg aggtcgtagt gggcctcgat gttgcgccgc
    22141 gagccgctgc gcgtgttggc gcgcagcagg tgctgcaggc ggtggctcag cagccggaac
    22201 atgcgcccgt agatcgcacc ctgcaggcgg gcgcggttgg ccgagagcag gcgcagcagc
    22261 ccagggaggt cctcggtgtc ccacaggccg tccatccagg tctcgccgaa gccgatgtcg
    22321 ccgcgcgcga gcgcctcgtc gaagacggcg tggtcgcgca cgcgcaggtg ggcgacgagc
    22381 gggccatggc cggcacgcac gcgcacgcca tcaggcagtt ccaccgcgat cgcaccgccg
    22441 tcgaggcggt cgagcatctc caggcacagc cgggtggcgc gcggcaggcg cgcgaggcgc
    22501 aggccggcga gcggctgcag ggcatggtcg agcgcgttca tcaggtggtc tcctcgatcg
    22561 gcggcgcggg cttgcggaag aagctcaccc gccgcagggc caggcgcagc gcctgccagt
    22621 ggatgcgggc gatgacgccc agggtcatga agggctggcg ggcgagccat ttccccatgc
    22681 tagcgccgct gaccgcttcg gcacggcccg acaggcgggt ggacagctgg cgctcgccgc
    22741 cgtcccagag ctcgatcgac accgcatgca ccgcgccgcg ctgctcgaag cggaagcggt
    22801 actcgccgcg caccgggaag aagggcgaga cgtggaagcg cttgctggcg cgcagctcgt
    22861 cgcccgcgac gatggggcgc aggtcatcgt ggtgcagcag gtagttgtgg cgttcgccga
    22921 aggtgttgtt cacctcggcc agcaccgcgc gcaggttgcc cgtgcggtcg tggcagaacc
    22981 agaagctgac cgggttgaag acgaagccga ggatgcgcgg catggtctgc agcacgacct
    23041 cgccgtcgca cgccgcggcc agcccgcgct cgtccaggag agcgcggatc cacggcaata
    23101 ggggcgagcc gtcgcgcgcg ccgtgatcgc ggctgcggaa gctgatgagg ttggcacgct
    23161 cgatgccgag cagcggtgcg cgtacccgat ccagccggcc gagcggcagg cgcaggaagg
    23221 cgctcgggta gacgaagcgg ttgtgcgcct gcacatggcg ctcgtgcatg accgcgccga
    23281 agcacacggc aggttgcagc gcgtcggaca tcacgccgcc tccaacgcca tcgcggcagg
    23341 cacgcggccg cgccgccacg gcacctccac gcccatggcc tcgaccaccg cgaccgcgga
    23401 cttgaggccg tcctcgtgga agccgtagcc ggtccatgcc ccggcgaacc agcagcgctc
    23461 gcggccctgg atggcgggca gcgcggcctg ggcgtcgatc gcgccgtggt cgaacactgg
    23521 gtgggcgtac tcgatgcggc ggaaggtctt gtcggccgcg ggttcggtga aggggttcag
    23581 cgataccacc accggggtct ggaaaggcag gggctgcagg cggttgatga gatagcttac
    23641 cgacaccggg cgcgcgtcgg gcgcgccctt gccggcgagg tagttccacg ccgaccacac
    23701 cttttgccgg cgcggcagca gggcggtgtc ggtgtgcagc caggcgacgt tggcctggta
    23761 ctgcaccgcg ccgaggacgc ggcgctcttc cgccgtggcc tcgctgccga ggatggcgag
    23821 ggcctggtcg ctgtggcagg cgaagacgag ttcgtcgaag cgctccgccc cgcccgcggt
    23881 atgcacccac accccgtcct cgccgcgcac cacgcgctgc accggcgaat tcacccgcac
    23941 gtcgtcgaga cgggcgagca tgcggcgcac gtagctgcgc ccgccaccct tcaccgtcat
    24001 ccaggtcgga cggtcgagga tctgcagcag gccgtggttg tggcagaact gcacgaaggt
    24061 ggcgagcggg taggccagca tggtgcgcgt cgggcaggac cagatcgccg cagccatggg
    24121 cagcaggtac cagtcgcgga aggcctgcga atagtcctcg aggtcgaggt actcgccgag
    24181 cgacagggcc ggcatggcac cctcgtgcgc catgcgcgtg gtctcgcggt tgaagcgcag
    24241 gatgtcgcgc agcatggcaa ggaaggccgg gcggaccagg ttgccacgct gggcgaatac
    24301 gctggcgagg tcggtgccgg cccattcgag ctcgggctcg gcgaggctga cgccgaagct
    24361 catctcggtc tcgaccgcct cgacctgcag caaggcgaac agcgcgcaca ggttgggata
    24421 ggtgcggcgg ttgaagacca ggaagccggt gtcgaccgga tgggtgaggc cgtcgaccgt
    24481 gacgtcgatg gtgttggtgt ggccaccgac gtagctgccc gcctcgaaca gcgtcacgcg
    24541 gtgctgcggc gcgagcagcc acgcggtcga gaggccggcg atgccgccgc cgatcaccgc
    24601 gatgcgccgc ccctggctgc cctggcccgc ctcgcctgcg gcgtgcaggc gctcgatctc
    24661 acccatcttc atggcactta ctccggcgcg ttctcgccct cgatgagggc gtaggcggaa
    24721 tggttgtgga tggactcgaa gttctccgac tgcacccgcc acgaagccac gcgcgcatcg
    24781 gcgcgcaggc gcagcgcgat gtcgcgcacg aggtcctcga cgaacttggg gttgtcgtag
    24841 gcgcgctcgg tgacccactt ctcgtccggg cgcttgagca ggccgaagac ctcgcacgag
    24901 gcttcttctt cagccatgcg caccagctcg cgcaggccga ggtcgccgcg cagcgtggcg
    24961 ctcagggtga tgtgcgagcg ctggttgtgg gcgccgtagg cggagatctt cttcgagcac
    25021 gggcacaggc tggtgaccgg caccaccgcc tcgagcgtgc tgcggatctc gccgccctcc
    25081 gccttctcca ccaccacgcg ggcgtcgatg tcgagcaggc tctcgacgcc cgagaccggc
    25141 gcggccttct tcatgaacca ggggaagcgc gcctcgatgc gaccgctgct ggcctcgagg
    25201 cgcagcagca tgtcggcgaa gaggccgcgc aagccgtcga ggtcgagcgc atcgcgctcg
    25261 gcttcgagga gctcgacgaa gcgcgacatg tgcgtaccct tgacgtccgc gggcaggccg
    25321 acggtcatct ccagcgtggc gacggtgtgc tgcacgccgc cgtcgaggtc gcgcaccgcg
    25381 atcgggtagc gcaggccgcg cactccgacc tgctggatcg ccagcgcgcg gtggtcggcg
    25441 ctggattgca cgtcgggcag gaagaacttt tccggggcgt tcatgagtga tccttttgct
    25501 tgctggggag gggacgcagc gggaggtccg cgcgatggac gaagagcagg agttcgagcg
    25561 gggtctgtgc ctgggtcaca ggccccttgt ctacgacgag cctttcagga gcgccggccg
    25621 ctaccgccgc gacgacctgg ggctgggcgg ccgtggccgc ggaaatcccg aaggagacga
    25681 gcgccgccgc ggcgaagagc atgccggcgc gcctggagag cgtattcgca ttcatggccg
    25741 tgtcctggac aagcgttgat gacgatccca cgataggcca gccccgagga cctgtcaagg
    25801 atttgtccag gacaaaataa aatttcagcg ccccgcagaa attgccccgg catcctccga
    25861 gaacaatgca ctccccgccg cggcgatccg gcattacgct ttccctaaga cccccccatc
    25921 ccgcacgaga ggcccgccct ggacaccagc tcgctcgcca tctacccgat cgtcgccggc
    25981 ctgctcggcg gcatcggcct gttcctgctc ggcatgcaca tgctcaccga gggcctcaag
    26041 ctcgccgccg gccgcgcgct cgagggcctg ctcgagcgcg gcaccgccac gcccgtgcgc
    26101 ggcctgggcg ccggcatgac catgaccgcg ctggtgcagt cctccaccgc ggtcacggtg
    26161 gcgagcatcg gcttcgtcaa caccgggctg ctgtcgctgc agaacgcgat gtgggtgatc
    26221 ttcggctcca acgtgggcac cacgctcaac gcctggctgg tcgcggcgct cggcttcagc
    26281 ttcaggatcg acgccttcgc cctgcccttc gtcggcatcg gcgccaccct gatgctggcc
    26341 ggacgcacgg tccgccagcg cgcgctcggc caggcgctgg cgggcttcgg cgtgctcttc
    26401 ctcggcatcg acgcgctcaa ggacaccttc tcgggcttcg gcgcggcgat gaacctgcag
    26461 gaccacatcg cgcccggcct cgccggctgg ctgatcctgg tcggcatcgg caccctgctg
    26521 accgtgctga tgcaggcttc gggcgcggtg atcgcgatca tcatcaccgc cgcgcagggc
    26581 gggctgatgt cgatcgaggc ggcgtgcgcg atggtgatcg gcaccaacat cggcacgacc
    26641 tcgacggcga tcctttcggc gctcggcgcg acctcgaacg cgcgccggct ggcagcgacc
    26701 cacgtgatct tcaacctggt gaccggcgcg gtggcgatcg ccctgctgcc gctgctgatc
    26761 agcctgctcg gtgcgctgcg caactggttc gagcagccgg ccacgccggc ggtgatgctg
    26821 gcgatgttcc acaccgcctt caacctgctc ggggtgctgc tgatggtgcc gctggcgcgg
    26881 ccgctgcggc gctatctggc gggccacttc cgcagccgcg aggaagagat cgcccgcccg
    26941 cgctacctgg acgcgccttc gctggcggtg cccgacctgg cgctgcgcac cctgcgcctg
    27001 gagctgggcc gcacgcaatc cttcgcgctg accgcactga ccgcagccac ccgggtgccg
    27061 cccgacgagc cctggatcga gcgccaggcg agcgcgctcg atgcgctcgc gccggcgatc
    27121 ggcgactacg tgcgcaagct caacgccatg cgcctgccgc cagcgctggt cgaggcggtg
    27181 gcgcacagcc tgcgcgcgct gcagtaccag gagagcgcgg tgaccgcggt gcgccaggcc
    27241 tgcgcgctgg ccaccacgct cggcgcgccg ccgggcgccg aactggagcc ggtcgccgcg
    27301 gccttccgcc aggcgaccgg ggcgctggcc gcgagcgcgg acgcggcgcg cgaggatttc
    27361 tcggtggcgc cggtcgaggt caggctggaa gaggcggaac tgcgctacca ggccttcaag
    27421 gaggcgctgc tgctggaagg cgcacacgcc cgcatcgaca tccgcaccat gcaggactgg
    27481 ctgcgcctgg ccagcctgga gcggcgcgcg atcgagcagg tggccaaggc ggcgcgcatg
    27541 ctggccgtgc tggacggcga cctgacgccg cagcaggcgg cggagaaggc gggagaaaac
    27601 ggggtggagt gagcgcggag gcggagtcat gtgctaccgg gtggagtgct ggtcggacgg
    27661 aagcgtgggc gcgtgcgatc cggctgcccc gacctcgcac gtcacaggct ggaaagcggc
    27721 ttccagacac gtttgtcctg gacaaatcaa actcccccgc ctaacatcga ctcatcgacc
    27781 accacccgaa agcagctgcc gatgaacgcg ccgaacctgt ccgagaccgc cttcagcatc
    27841 gccgccgtcg aacgcgacac gggcctcgcg aaggacaccc tgagggtgtg ggagcggcgc
    27901 tacggcttcc cttcgccgac gcgcgacgcc aacggcgagc gcctctatcc ggcggatcag
    27961 gtcgagaagc tgcgcatgat ccgccgcctg ctcgaccacg gccgacggcc ggcgcgggtc
    28021 gtgggggcga gcatcgagga actctccgcg atgctggatg cctgcctgtg cccggagggc
    28081 ggcgcgccag ccggtcgcga cgacggcctg ctgcagctcg tgcgcctgca tcgcagcgtg
    28141 gagctcgccg cggcgctgcg ccaggcgctg atgaagcagg gcctgcagcg cttcgtcgcc
    28201 gagaccgtgg cgccgctcgc ggcggcggtg ggcgaggcgt ggatgcgcgg cgaggtcgat
    28261 gtgccggagg agcacctgtt caccgagcag gtgcagaacg tgcttcgcag cgccatcggt
    28321 gcgcatgcgg cgagcgctgg acggccgcgc gtgctgttga cgaccttccc cgaggaggag
    28381 cacgtgctcg gcctgctgat ggccgaggcg atgctggtgc ccgagggcgc gagctgcctg
    28441 tcgctgggca cgcgcacccc gctcgcggac atccgcagcg cggcggtggg tgggggcttc
    28501 gacatcgtcg ggctgtcctt cagcatcgcc tacccggcgc gccaggcgat cgaggggctg
    28561 ctcgagctgc gctcgctgct gcccgagggg atcgagctgt gggccggggg cgccgccgtc
    28621 cgcgacaagc agaagcggct gccgggcatt cgtgtggtcg gggatctgga ggacaccatg
    28681 gcggccctgc aggagtggcg cgcgcgcaac ggcgcggagg gctgaggcgc acgcagcgac
    28741 cggcgcggcg gtttgtgtag gagcggcggc agccgcgaat ggggccgggt cgacgaccac
    28801 ggcacagcga gggttccacc cgccgcgttc gcgcctgccg gcgctcctac atgaaacgcc
    28861 gcgcctcctg cacgaaccac cgcgtctccg ccccctgtag gagcggcggc a
//
LOCUS       DAOTIN010000035        28808 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_1851_length_28808_cov_8.589886, whole genome shotgun sequence.
ACCESSION   DAOTIN010000035 DAOTIN010000000
VERSION     DAOTIN010000035.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 28808)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 28808)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28808
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1851_length_28808_cov_8.589886"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1282
                     /locus_tag="P5537_07420"
     CDS             <1..1282
                     /locus_tag="P5537_07420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV77910.1"
                     /translation="LAFLAVGLVDSLHYRPLLSAVERVAGVGAPAGSAPAAPVVSTEV
                     LSALDALLAPLRLRTEKTYSAPFAWTLYQRETVETADGGQVRDYPRLTYGAAHLGADV
                     AAARGGDVALRLVSALAQAALAWLVAFLVLASLVWRGSGLRWGEVARAMLAGRTVLAW
                     RAALVTLAVLLAVAAVCVELAPLYHVLGTDKVGQDVLYLALKSVRTALVIGTLTTLVM
                     MPFAVALGIAAGYLGGWVDDAVQYVYTVLNAIPGVLLIAAAVLMMQVVIDTHPQWFDT
                     AAERSDARLLALCFILGITSWTGLARLLRGETLKLRELEYVQAARAFGVRTPAILRRH
                     ILPNLMHIVLIALVMDFSGLVLAEAVLSYVGIGVDPSTISFGTMINMARAELAREPMV
                     WWSLAAVFAFMFVLVLAANLFADVVRDAFDPRRA"
     gene            1332..2906
                     /locus_tag="P5537_07425"
     CDS             1332..2906
                     /locus_tag="P5537_07425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiU family protein"
                     /protein_id="HRV77911.1"
                     /translation="MRALRFDNRFVRELPADPEPDNHVRPVHGACYSRVMPTPVKAPH
                     LLAWSREVAEILGLDEADVRSAEFARVFGGNGLLPGMEPYAACYGGHQFGNWAGQLGD
                     GRAITLGESINARGERWELQLKGAGPTPYSRFADGRAVLRSSLREFLCSEAMHHLGVP
                     TTRALSLVGTGETVVRDMLYDGNPRAEPGAVVCRVAPSFIRFGNFEIFASRGEEALLE
                     RLIDFTIARDFPELAAETDAAARRIRWFDEVCRRTAVLVAHWMRVGFVHGVMNTDNMS
                     ILGLTIDYGPYGWVDDFDPEWTPNTTDAGGRRYRFGNQPYIAHWNLWQLANAIYPVVR
                     EVEPLERALAAYAEVHDASYRDMMRAKLGLAEWRVGQEGDDGLLERLHRLLAAGEVDM
                     SLFFRRLAEVDPAAPALEPLAEAFYDPARRATADAELLGWLREHGARVLAEGQPAAAR
                     RAAMNRVNPLYVPRNYLAQQAIDAAEAGDTAELETLLEVLRRPYDEQPGRERFAARRP
                     DWARDRPGCSMLSCSS"
     gene            3090..3851
                     /locus_tag="P5537_07430"
     CDS             3090..3851
                     /locus_tag="P5537_07430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HRV77912.1"
                     /translation="MSTIVLTQADESHVRPALPRKATSPRDALARMPILLGSGAAVLD
                     ELAQGAEFVRLSSSATVFERGSQPTGLFFVCNGAVRLMVSGPEGKDKVVELFEPGGMF
                     GEIGVFTGARYRTWTQAVGSVVLIHVPRERVLAAVALDNALSNRMLVAVCARIQRLID
                     AIGSTAGGPAAVRVASYLLEQLERGARSDGCIILPAPKKTIASLLNLTPETLSRVLRN
                     LVEEGVLTVSGRRIRVRNRAQLARLLTHDEAVLPL"
     gene            4041..5264
                     /locus_tag="P5537_07435"
     CDS             4041..5264
                     /locus_tag="P5537_07435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite transporter"
                     /protein_id="HRV77913.1"
                     /translation="MSTTAFTVCFAVWMLFAVIGIPIKEVLALNETQFGLLAATPVLT
                     GSLIRLPLGMLTDKFGGRIVFFVLMLCTVLPIYLIGHATEYWQFLVAGLFVGFAGGSF
                     SVGIAYCARWFERQNQGFAMGVFGAGNSGAAVTKFVAPTLVVMFGWQMVPQVYAAAML
                     ITAIAFWFFTYDDPEHRVHSSVTFRDQLRVLKDPRVWKYCQYYSIVFGGYVGLSLWLT
                     KYYVNEFGMGIQTAALLAACFSLPGGVLRAVGGWLSDRYGAHKVTWWVMWASWICLFL
                     LSYPNTEFTVQTVEGPRTFSIHLNVWVFTFLLFIVGIAFAFGKASVFKYISNEFPKEI
                     GAVSGIVGLVGGMGGFLLPIMFGALVDLTGVRSSAFMLLYGVTWVSLIWMYLTEVRRV
                     DMFDGHETAVDSSRA"
     gene            5292..6947
                     /locus_tag="P5537_07440"
     CDS             5292..6947
                     /locus_tag="P5537_07440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HRV77914.1"
                     /translation="MQASNVAASSPAVTSSVDLVDWRPEDETFWKEKGSRIANRNLWI
                     SIPSLLCGFAVWLMWGIITVQMANAGFPFAPDQLFSLAAIAGLAGATTRIPASFFIRI
                     CGGRNTVWLTTALLMIPAVGTGIALQSLETPLWVFQLMALLSGMGGGNFACSMANIST
                     FFPKRLQGTALGLNAGLGNFGVTTSQLLIPAVMTMGVFGALGGDAIPLVKDSATLIGK
                     IAAGTPTYVQNAGFVWLLLLVPLAVVGWFGMNNLLTVSPNIGSTGAALGKIILFYGIA
                     LVVSAIGLYLYLPSGLGVLAGGGMWIMLPLVILGTLYGMKFAASGEMKTNLDKQFAIF
                     RNKHTWSMTALYVVTFGSFIGFSMALPLSITVIFGNTHVLDPATQAWVHAKNPNAPSA
                     LMFAWIGPFVGALIRPVGGWISDKLGGSIVTQWISIVLVIASAVTGYVMFLAYHSATP
                     EEYFFVFMALFVLLFAASGIGNGSTFRTVGFVFDKDERGPVLGWTSAVAAYGSFIAPV
                     VIGGQIKAGTPEYAMYGFAVFYALCVVLNWWFYLRKDAYIQNP"
     gene            7036..10791
                     /locus_tag="P5537_07445"
     CDS             7036..10791
                     /locus_tag="P5537_07445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009325 - nitrate reductase complex
                     [Evidence IEA];
                     GO_function: GO:0008940 - nitrate reductase activity
                     [Evidence IEA];
                     GO_process: GO:0009061 - anaerobic respiration [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit alpha"
                     /protein_id="HRV77915.1"
                     /translation="MSHFLDRLRFFDKVKETFSNGHGIVTNEDRNWEDAYRNRWRHDK
                     VVRSTHGVNCTGGCSWKIFVKNGLVSFEMQQTDYPRTREDLPNHEPRGCQRGASFSWY
                     LYSPHRIKYPMIRGRLLDLYRAERKAGRDPVEAWEAIQKDPAKREKYVHVRGLGGFVR
                     TSWDEVTEIVAAANVYTIKKWGPDRIYGFSPIPAMSMISYAAGARYLSLIGAACGSFY
                     DWYCDLPAASPQTWGEQTDVPEAADWYNSTYLIITGANLPMTRTPDAHFATEVRYKGT
                     KIVSMAPDYAEYVKFADLWMPVKQGTDAAAFLAMGHVALKEFLVEKQDPYFTEYARKY
                     TDLPMQVVLRKYGEGYVSDRNLRASDFDNNLGEANNPEWKTIVFDKKSGRFIAPNGTI
                     GFRWGEEGKWNLLEKAGADQAETEAELTCMGSHDEVVSVGFPHFVPGEPALLYRNVPA
                     RRLKLANGEEAFVTSVFDMQVAQYGIDRGLGGGNVASSYDDANVAYTPAWAAKQTGVK
                     AADLERTGREFAENASKTRGRSMVIMGAAINHWYHNDLAYRAIMNLLHMCGCVGQTGG
                     GWAHYVGQEKLRPQAGWAPIAFALDWQRPPRHMNSTSFWYFHTDQWRYETVDADSLLS
                     PAGPCRNKGSSLADYNVKAVRMGWLPSAPHFNRNPIELAEEAARAGATDEASVSKYVV
                     DQLKSGALDVSFADPDAEENWPRNLIVWRANLIGSSAKGHEYFLKHLLGAQNGVMQEG
                     GAGNNCKEVKWREHGPTGKLDLMVDVNFRLNSTGAYSDIILPTATWYEKNDLNTTDMH
                     PFIHPLGEAVTPGWESKSDWQIFRTLAKTFTALGAKHLGTRKDVVSLPMQHDSPTELA
                     TPMGVGKDWKHGECEPIPGKTMPMLKLVERDYGQIYNKYIALGPLMVKLGNNVKGLDW
                     DTTQEYEELKKCNYPVQVEGVSKGMPSLEEDIYVCDSVMRMAPETNGEVAHKSWSALS
                     KKTGIDHHHLYAGRHEDKITFRDIVAQPRKIITAPTWSGIESETVSYTAGYTNIHEHI
                     PFRTLTGRAHFYQDHEWFLDFGEGFCTYKPPVDLKAHEKVPDSVRNKPHLTLSWITPH
                     SKWGIHSSYQDNLRMLNLFRGGPYVWLSEEEAATIGIKDNDWVEAINANGATVARAVV
                     SQRIPRGMAIMYHAQEKNVNVPGSNTTGKRGGILNSVTRVIVKPTNMVGGYAQLAYSF
                     NYYGTVGCQRDEVVVIHKIEDQDIDWLERPLTPEREAQRNPVGIGKK"
     gene            10827..12398
                     /gene="narH"
                     /locus_tag="P5537_07450"
     CDS             10827..12398
                     /gene="narH"
                     /locus_tag="P5537_07450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009325 - nitrate reductase complex
                     [Evidence IEA];
                     GO_function: GO:0008940 - nitrate reductase activity
                     [Evidence IEA];
                     GO_process: GO:0009061 - anaerobic respiration [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit beta"
                     /protein_id="HRV77916.1"
                     /translation="MKIRAQFAMVFNLDKCIGCHTCSVTCKNVWTNRKGVEYAWFNNV
                     ESKPGIGYPKEWENQDKWKGGWTKLNGKLELKAGGRLKKIVQIFSNPNLPEIDDYYEP
                     FTYDYARLQNAPLSEAAPTARPVSQITGEKMDKITWGPNWEDDLAGEFASRARDKNFS
                     NMEKEMYKQFENTFHMYLPRICNHCINPACVASCPSGALYKREEDGIVLADQDRCRGW
                     RMCISGCPYKKVFFNWESSKAEKCVGCYPRVENGMPTVCSESCVGRIRYNGIILYDAD
                     KVSAAASADNVQDLYQEHLDMFVDPFDPAVIEQAKKDGITDDWILAAQKSPIYKMAVQ
                     WKIAFPLHPEYRTLPMIWYVPPLSPVQSQIDQKALPTEADGVIPKASAMRLPVKYLAN
                     LMTAGKEQPIVDALNRMIAMRSYQRSVHVEGTPDTRALDAVGMTEDMAKEMYRYLAIA
                     NYEDRFVIPTSKEEMRLEDYHGFQGQAGFSFGSASSVGISPNSLFPERRKESMEPRKP
                     VPHADEMHDVTGERY"
     gene            12411..12959
                     /gene="narJ"
                     /locus_tag="P5537_07455"
     CDS             12411..12959
                     /gene="narJ"
                     /locus_tag="P5537_07455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0051131 - chaperone-mediated protein
                     complex assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase molybdenum cofactor assembly
                     chaperone"
                     /protein_id="HRV77917.1"
                     /translation="MQTYKLLAVLLDYPGSEIVGDLRAAVSEQGGARGLVRSVDTDKV
                     FTEAEHESIAGFIDWMLAQDQTELEGRFVKTFDLTPEHSLHLTHHVFGDDKNRGPALI
                     DLSEFYKSYGLQHDEHEIPDYLPMMMEFVSQLEETEARVFLTDAVKVFNVLATNLEKA
                     ESPYAALVRVIENHSSLARMAA"
     gene            12970..13662
                     /gene="narI"
                     /locus_tag="P5537_07460"
     CDS             12970..13662
                     /gene="narI"
                     /locus_tag="P5537_07460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009325 - nitrate reductase complex
                     [Evidence IEA];
                     GO_function: GO:0008940 - nitrate reductase activity
                     [Evidence IEA];
                     GO_process: GO:0019645 - anaerobic electron transport
                     chain [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase subunit gamma"
                     /protein_id="HRV77918.1"
                     /translation="MSLTNLIFGVYPYIALTVFVIGSWIRYDNEQYTWKTDSSQLLSK
                     QGMMLASNLFHVGIIMIFFGHFAGLVLPHGLWLGLGISDLAHQWIAIIAGVIFGIMCL
                     VGGSMLWYRRMYNPRVRINSRRSDVFIITWLMATLILGLLTVPFSIGHAAKGDPAVML
                     ALAEWVKSILLLNPQPELMTKVDPIFRAHIFFGMTVFLVFPFTRLVHILTAPFSYLTR
                     AYQIVRTKRRLA"
     gene            13767..15710
                     /locus_tag="P5537_07465"
     CDS             13767..15710
                     /locus_tag="P5537_07465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pili methyl-accepting chemotaxis
                     transducer N-terminal domain-containing protein"
                     /protein_id="HRV77919.1"
                     /translation="MFIRSSGLSVKITGMLLGFFLVALAAIALTLFISWHLEGAAAAI
                     NDAGSLRMRVYRLAHHLARADVEKIDRSAFAADLQERIDDFDAVLSVLRRGDPSRPLF
                     VPREDGIPEDLAKMADNWATRSRPILSAIVADPSPQNLHLRGLEFDAAAEACVDSINQ
                     LVLRMEQSYARNTNILRTSQVILIALAVIGTILLLRFFFLTVIRPVFELHEGVKRMGQ
                     EDFDARVPVLSKDEFGELSAGFNRMAAHLQSVYDTLEERVAAKTRSLEEKNRELEILY
                     DIVAFLREPNDVDTLCKGFLERVQKTLGASASSARLLDLESRNLCMIVHDGLGEDFLD
                     REEVLACGECVCGEAAQGSGLSLTLDVRNASLAVTRDACLRAGFRTVSATSITANKRA
                     LGVFNLYFDHSQPIGDADRQLLETLGQQLGIAIENQRLHARERELAVSEERNLLAREL
                     HDSIAQGLAFLNLQVQMLERALAEQRAEDVRTTVEMLRRGIQESYEDVRELLVHFRTR
                     VEQQDLDAAIAAALRRLAEQTGIATDLDVQGDGAPLDPEAETQVLYIVQEALSNVRKH
                     AGAGTVSVSVRRGRDGLAVTVRDDGVGFAEDRDTTDGEAHIGLQIMRERALRIGGRFA
                     VRSSPGRGTEIRLELPRTNEVEA"
     gene            15710..16438
                     /locus_tag="P5537_07470"
     CDS             15710..16438
                     /locus_tag="P5537_07470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HRV77920.1"
                     /translation="MTEAKIRVLLVDDHTLFRSGIRSLLQSYACFEVVGEAGDGREGI
                     RLAGQLRPDVVLLDNNMPGLSGREAARLMLEEAPETRVLMLTVSEDADDLIETLRAGA
                     CGYLLKNIQAETLVSAIKTAAQGESVVSPQMMGKLLSGVRGTPGRAASGGLPPAPAPQ
                     GRSTSVTGAEAAELDKLSPREREILQFIARGQSNKEIARALELAESTVKIHVQNMLRK
                     LNLSSRVQAAVFAVEKGLGQGPET"
     gene            complement(16475..16882)
                     /locus_tag="P5537_07475"
     CDS             complement(16475..16882)
                     /locus_tag="P5537_07475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HRV77921.1"
                     /translation="MNTPLDKSEFEALADFRYQLRRFLRFSELLTRRHGITNLQYLLL
                     LQVKGYPGREWACIGELAERLQAHQHGVVSLVSRCEKLGLVERRPGREDRRAVEVHLT
                     AEGERLAETIALHHREEVKLLGGVFRDLASQLR"
     gene            17060..17632
                     /locus_tag="P5537_07480"
     CDS             17060..17632
                     /locus_tag="P5537_07480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0031267 - small GTPase binding [Evidence
                     IEA];
                     GO_process: GO:0006888 - endoplasmic reticulum to Golgi
                     vesicle-mediated transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Yip1 family protein"
                     /protein_id="HRV77922.1"
                     /translation="MDVMQFPRMVVSSRDGWDLVAQARPPMDWLFRRLVLPMSLLPPL
                     MILLASGGVGERVFPEAGFGNWLIAAVLFFVAEHFSVPIMANSIRQASMAKDGSNRLE
                     DAYAVAAIAPVPLWLSSLAVVFGSAWFVVLVGLVALGASAMLIRHGVDRLLGIEEDVE
                     ASEVAMQVTSFGVLTWLVLLSIAAGAVMLL"
     gene            complement(17648..18094)
                     /gene="smpB"
                     /locus_tag="P5537_07485"
     CDS             complement(17648..18094)
                     /gene="smpB"
                     /locus_tag="P5537_07485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HRV77923.1"
                     /translation="MSIIENRKAFHDYFIEEKHEAGIVLEGWEVKAIRAGRSNIKESY
                     VVIRGEEIFLFGMHITPLTTASSHVRHDPTRTRKLLLHKKEIARLIGKVERAGYTLVP
                     LDLHYKKGLIKLEIGLAKGKKLHDKREDEKKKDWEREKQRLMRVKA"
     gene            18217..18669
                     /locus_tag="P5537_07490"
     CDS             18217..18669
                     /locus_tag="P5537_07490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RatA family
                     toxin"
                     /protein_id="HRV77924.1"
                     /translation="MAEVNKLVLIEFTPEQMFELVDRCEEYPLFLPWCGGTELIERTE
                     TITAATLHINYHGIKAHFSTENTKRYPQEMKLRLTDGPFTHLDGLWRFTALGDTACKV
                     EFQLRYQFASKLLEKVLGPVFNHIANTFVDSFVKRAGQVYRAGQGSAA"
     gene            18666..18992
                     /locus_tag="P5537_07495"
     CDS             18666..18992
                     /locus_tag="P5537_07495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfH family protein"
                     /protein_id="HRV77925.1"
                     /translation="MSGLINVEVVYALPQRQELVHVRLAEGATVRDALEASGLLQKYP
                     DIQPDRANKLGVYAKLVKLDTEVRDRDRVEIYRPLIADPKAVRKKRADEGKVMKKGGG
                     PAEAAE"
     gene            complement(19077..19568)
                     /locus_tag="P5537_07500"
     CDS             complement(19077..19568)
                     /locus_tag="P5537_07500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4124 domain-containing protein"
                     /protein_id="HRV77926.1"
                     /translation="MNRRLAPVAILALLLNALPACAQVYSWKDKDGRTHYGDMPPAAV
                     EATLLRGAPPARPSGEASSAADPQPSVSPSSPRSLTEREQAFQERRAAEAEAEAKRAE
                     EAAARDETQRFCTSAQHELAALRAGQRMVRFNARGEREFLDDQARAEQMARLERQIAE
                     RCR"
     gene            19651..21114
                     /gene="guaB"
                     /locus_tag="P5537_07505"
     CDS             19651..21114
                     /gene="guaB"
                     /locus_tag="P5537_07505"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HRV77927.1"
                     /translation="MRVIQKALTFDDVLLVPAHSTVLPRDVSLQSQVTRRIRLNVPLV
                     SAAMDTVTESRLAIALAQEGGIGVVHKNLTPAQQAGEVHKVKRHESGILKDPITIPPT
                     MTVGQVIALQRQNRFSGVPVVEGGKVVGIVTNRDTRFETNLDQLVSEIMTPQDRLVTV
                     REGASLEEARELLRVHRLERVLVLNEAGELCGLITVKDMMKSTEHPLAAKDEQGRLRV
                     AAAIGVGAGTEERAERLADAGVDMIVVDTAHGHSQGVLDRVTWVKKHFPHIEVVGGNI
                     ATADAARALVDAGADGVKVGIGPGSICTTRIVAGVGVPQISAIDNVANALAGTGVPMI
                     ADGGIRFSGDIAKAIAAGANVVMLGGLFAGTEEAPGETVLFQGRSYKSYRGMGSLGAM
                     EKGAADRYFQEENTGNIDKLVPEGIEGRVPYKGSVTAVIHQLVGGLRASMGYLGCADI
                     PSVHARAEFVQISSAGMRESHVHDVQITKEAPNYQIS"
     gene            21187..22752
                     /gene="guaA"
                     /locus_tag="P5537_07510"
     CDS             21187..22752
                     /gene="guaA"
                     /locus_tag="P5537_07510"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011765314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HRV77928.1"
                     /translation="MAHQKILILDFGSQVSQLIARRVREQQVYCELHPFDVSDEFVRS
                     FGAQGVILSGGPNSVYEAEDWRAPQAVFELGVPVLGICYGMQTMASQLGGKVESSAKR
                     EFGYAEMRARGHSKLFTGIEDRTNAEGHGLLDVWMSHGDKVTGLPPGFKVIGSNESTP
                     IAAMADEARGFYGVQFHPEVTHTIKGREMIARFVHDICGCGHDWNMPDYIEEAVQKIR
                     EQVGDEEVILGLSGGVDSSVAAALIHRAIGDQLTCVFVDHGLLRLNEGKLVMEMFAGR
                     LHAKVVHVDATEQFMGHLKGVTDPEQKRKIIGREFVEVFQAEARKLPNAKWLAQGTIY
                     PDVIESGGAKSKKAHTIKSHHNVGGLPETLGLKLLEPLRDLFKDEVRELGVALGLPHD
                     MVYRHPFPGPGLGVRILGEVRQDFADLLRRADAIFIDELRAADWYDKTSQAFAVFLPV
                     KSVGVMGDGRTYEYVVALRAVQTQDFMTAHWAELPHSLLGKVSNRIINEVRGINRVVY
                     DISGKPPATIEWE"
     gene            complement(22901..24412)
                     /locus_tag="P5537_07515"
     CDS             complement(22901..24412)
                     /locus_tag="P5537_07515"
                     /inference="COORDINATES: protein motif:HMM:NF012493.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-related protein"
                     /protein_id="HRV77929.1"
                     /translation="MLVSPLIALMKDPIDGLAARGIAAAQFDSTLGTNEHRALMAALR
                     DGSLRLRHVAPERSGFYRPNLQLLVSAVDAGRRGDTLLGLLAQRAPGPTIVYVSLQKT
                     AETLAATLAAAAWPARAYHTGMKDDERAAVQEWFMASDRAIVVATIAFGMGVDKADIR
                     CVYHYNLPKSLENYAQEIGRAGRDGRPSTCHLLLVIRDVNVLEDFIHCDTPDKAALGS
                     LPDERFAEAGSELELALTDLAARHDLRLLVLRTLLTYLELDGFLEGGTPFYADYRFKP
                     LMSSAQILARFDGERRHFLAHLLRLAVKERLWFRIDPAAAARVLGCERERVVRALDWL
                     GEQAMLKVKVTGVRHRYRLLRAPDDREALATALHRRMLEREKAEHARLMQVLDSAGLS
                     ACHSAALAAHLGEILPQPCGQCTGCQGLAASVCERGTSAIPETLAVELGALRAGTGQA
                     LASPRAVARLLCGLPSPSLTRARLASHTLCGRCAEVPSEQVMQWAEDRLGAAA"
     gene            complement(24415..24594)
                     /locus_tag="P5537_07520"
     CDS             complement(24415..24594)
                     /locus_tag="P5537_07520"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77930.1"
                     /translation="MSTSEPILSALQHHFGHSRFRPGQQAVIEHLMAGRSAAAVFPTG
                     GGKSLCDQLPAPLPV"
     gene            24733..25647
                     /locus_tag="P5537_07525"
     CDS             24733..25647
                     /locus_tag="P5537_07525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HRV77931.1"
                     /translation="MNELRPRLFRDWSAIVRTTVKLWLEAQVFVHAAALAFFTVFSVA
                     PVVIVAVTVVGLVLGESAAEGRIAEQLEVAIGPEAAATIQTAVQNSRIQHSGLLPTVA
                     GFAAMLFGATTVFTQMQNALNAIWGVAPRPTRSSVFIYLKTRLLSLAVVLGIGLVLLV
                     SLSLSIFVRALVAFAQDWLPVPVGLIIGLDWAIALLVVTLLFATIFRVLPDVVLRWRD
                     VLPGAFVTALLFALGRALIAIYLSTTATASTYGAAGSLVLLLLWVNYSSLILLFGAAF
                     TRAYLEACGCAVRPRATAVLVHRQLIED"
     gene            complement(25678..27120)
                     /locus_tag="P5537_07530"
     CDS             complement(25678..27120)
                     /locus_tag="P5537_07530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative nucleotidyltransferase substrate
                     binding domain-containing protein"
                     /protein_id="HRV77932.1"
                     /translation="MAEENEFFRPIRDIEQRRVVSCGADDVLVDIVGRMREMSISCVV
                     VVEGERPTAILTDRDLRNKVIAAGRDPAGLRVRDVMSAPVITIGEEDVLYEALYRMSR
                     HGIHRLVVVDRKGALAGIVTVTDLLRLQAHSPHQLVLDIEKADSIDALRELHQRIQKL
                     IVHLAGTGIAIRDTVKLIANLNDQVLIRLIDLLRRDRYPDLTADFAFVVMGSEGRGEQ
                     TLSTDQDNAILYADSVQGEELARLEAFSHELIEALISIGVPPCPGGIMARNPAWRRSL
                     TAWKRELTQWLSAPTPENVMTGSMFMDLRPLYGRRELADTLREHALHYMSHEQGFLVR
                     MAQNMVNFAPPLGWFGRIKVDKSGEHRGEVDLKKAGIFAITDGIKALAMEARRLDGST
                     HDRMEALIEAGVLKAEQVADLRAAFDFLVRMRLRGQVEALRAGRKPGNYIALDQLNAM
                     QQGELRLAFEGVASFQSFIQQHFKLQLLRN"
     gene            complement(27173..28063)
                     /gene="cobA"
                     /locus_tag="P5537_07535"
     CDS             complement(27173..28063)
                     /gene="cobA"
                     /locus_tag="P5537_07535"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004851 - uroporphyrin-III
                     C-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0019354 - siroheme biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HRV77933.1"
                     /translation="MQAGTFRSDASPAGAVKSRFLRASRAALPPRGAPEGPGERPQPM
                     RAHGHGKVHLVGAGPGDPDLLTVKALRLITGAQAVVYDHLVGEAVVALIPPGARRLYA
                     GKEAGNHALPQHEINRLLVELAREGQDVVRLKGGDPFIFGRGGEEMQALLDAGIECEI
                     VPGITAAAGAASATGIPLTHREHAQTLVFATGHLKDDTVDLDWPALARPRQTVVIYMG
                     LGALEIICTQLISHGLAADTPAAVIHAATTPRQCGVHATLATLPGAVRAAGIRAPALI
                     MVGEVVALDPGLVLAAAATG"
     gene            28317..>28808
                     /locus_tag="P5537_07540"
     CDS             28317..>28808
                     /locus_tag="P5537_07540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c"
                     /protein_id="HRV77934.1"
                     /translation="MQKKGLFGSALALAILPLAMSSAWAADAPKLTAEEMEKGKLIYF
                     ERCAGCHGVLRKGATGKNLEPHWTKTAPDGTKLEGGTLKLGTERLEKIISYGTEGGMV
                     NYDDILTKEEINLMARYIQNEPPIPPEFSLKDMKDSWKLLVPVKDRPTKQMNKVNLKN
                     VFAI"
BASE COUNT         4618 a         9703 c         9716 g         4771 t
ORIGIN      
        1 gctcgccttc ctggccgtcg gcctggtcga cagcctgcat taccggccgc tgctgtcggc
       61 ggtggagcgc gtggcgggcg tcggtgcgcc ggccggctcg gcgcctgcgg cgccggtggt
      121 gtccaccgag gtgctgtccg cgctcgacgc gttgctcgcg ccgctgcgcc tgcgtaccga
      181 gaagacctac tccgcgccct ttgcgtggac cttgtaccag cgcgagacgg tggagacggc
      241 cgacggcggc caggtgcgcg actacccgcg cctcacctac ggcgccgccc acctcggcgc
      301 ggacgtggcc gccgcacgcg gtggcgacgt ggcgctgcgg ctggtgagcg cgctcgcgca
      361 ggcggcgctc gcgtggctcg tcgccttcct cgtgctcgcc agcctggtgt ggcgcggcag
      421 cgggctgcgc tggggcgagg tggcgcgggc gatgctcgcc gggcgtaccg tgctggcctg
      481 gcgcgcggcg ctggtgacgc tggcggtgct gctcgcggtg gcggcggtgt gcgtggaact
      541 ggcgccgctc taccacgtgc tcggcaccga caaggtgggg caggacgtgc tctacctggc
      601 attgaagagc gtgcgcaccg cgctggtgat cggcaccctg accacgctgg tgatgatgcc
      661 cttcgcggtc gcgctcggca tcgccgcggg ctacctcggc ggctgggtgg atgacgccgt
      721 gcagtatgtg tacaccgtgc tcaacgccat ccccggcgtg ctgctgatcg ccgcggcggt
      781 gctgatgatg caggtcgtca tcgataccca cccgcagtgg ttcgacaccg ccgccgagcg
      841 ctcggacgcg cgcctgctgg cgctgtgctt catcctcggc atcaccagct ggaccgggct
      901 ggcgcgtctc ttgcgcggtg agacgctcaa gctgcgcgag ctcgagtacg tgcaggcggc
      961 gcgcgccttc ggggtgcgca ccccggcgat cctgcgccgc cacatcctgc ccaacctcat
     1021 gcacatcgtg ctgatcgcgc tggtgatgga cttttccgga ctggtgctgg ccgaggccgt
     1081 gctgtcctat gtcggcatcg gcgtcgatcc gtcgacgatc agcttcggca ccatgatcaa
     1141 catggcgcgt gccgaactcg cgcgcgagcc gatggtctgg tggtctttgg ccgcggtctt
     1201 cgcgttcatg ttcgtgctcg tgctcgccgc caacctgttc gccgacgtgg tgcgcgacgc
     1261 cttcgatccg cgccgcgcct gagcacgccc tcgcccgcat ccgccgggcc gaccatgacg
     1321 aggattcccc gatgagagcg cttcgcttcg acaaccgctt cgtgcgcgag ctgcccgccg
     1381 atcccgagcc cgacaaccac gtccgcccgg tccatggcgc gtgctactcg cgcgtgatgc
     1441 ccacgccggt aaaggcaccg cacctgctgg cgtggtcgcg cgaggtggcg gagatcctcg
     1501 gcctggacga ggccgacgtg cgcagcgccg agtttgcccg cgtcttcggt ggcaatggcc
     1561 tgctgcccgg catggagccc tacgccgcgt gctacggcgg ccaccagttc ggcaactggg
     1621 cggggcaact cggcgacggg cgcgcgatca cgctcggcga gtcgatcaat gcgcgcggcg
     1681 agcgctggga gctgcaattg aagggcgccg ggccgacgcc gtattcgcgc ttcgccgacg
     1741 gccgcgcggt gctgcgctcc tcgctgcgcg agttcctgtg cagcgaggcg atgcatcacc
     1801 tcggcgtgcc gaccacgcgc gccttgagcc tggtgggcac cggcgagacc gtggtgcgcg
     1861 acatgctcta cgacggcaac ccccgggccg agccgggcgc ggtggtgtgc cgggtggcgc
     1921 cgtccttcat ccgcttcggc aacttcgaga tcttcgcctc gcgcggcgag gaggcgctgc
     1981 tcgagcgcct gatcgacttc accatcgcgc gcgatttccc cgagctggcc gccgagaccg
     2041 acgccgcggc gcggcgcatc cgctggttcg acgaggtgtg ccggcgcacc gcggtgctgg
     2101 tggcgcactg gatgcgggtg ggcttcgtgc atggggtcat gaacaccgac aacatgtcca
     2161 tcctcggcct cacgatcgac tacggcccct atggctgggt ggacgacttc gaccccgagt
     2221 ggacgcccaa caccaccgac gcaggcggcc ggcgctaccg cttcggcaac cagccctaca
     2281 tcgcgcactg gaacctgtgg cagctcgcca acgcgatcta cccggtggtg cgcgaggtcg
     2341 agccgctgga acgtgcgctc gccgcctatg ccgaagtgca tgatgcgagc tatcgcgaca
     2401 tgatgcgcgc caagctcggc ctggccgaat ggcgcgtcgg gcaggagggc gacgacggcc
     2461 tgctcgagcg cctgcaccgc ctgctcgcgg ccggcgaggt ggacatgagc ctgttcttcc
     2521 gccgcctcgc cgaggtcgat ccggcggcgc cggcgctcga gccgctcgcc gaggccttct
     2581 acgaccccgc gcggcgggct acggcggacg ccgagctgct cggctggctg cgcgagcacg
     2641 gcgcgcgcgt gctcgccgag ggccagccgg ccgcggcgcg gcgtgcggcg atgaaccggg
     2701 tcaaccccct ctacgtgccg cgcaactacc tggcgcagca ggcgatcgac gctgcggagg
     2761 cgggcgacac tgcggagctc gagaccctgc tcgaggtgct gcgccggccc tacgacgagc
     2821 agcccgggcg cgagcgcttc gccgcgcgcc gaccggactg ggcgcgcgac cggcccggct
     2881 gctcgatgct gtcctgcagc tcctgaacgc cggtgggccg gcgcgcgccg ccgccagcgc
     2941 atgcctcctg cgggcggacc ggacgggcgg gatagtcctt tcggagtagc gctccttcga
     3001 tcggccaatg gctatcggtc ctgccacggt ctaggatgga atcggaggag gaaccgtcgc
     3061 aacccacgcc gacggaacga aaaagaaccg tgtccacaat cgtcctgacc caagccgacg
     3121 agtcgcatgt tcgtccggcg ctgccgcgca aggccacttc gccacgcgac gccttggcgc
     3181 gcatgccgat cctgctcggc agcggggccg cggtgctcga cgaactcgcg cagggcgccg
     3241 agttcgtgcg cctgtcctcc tcggccacgg tcttcgagcg cggctcccag cccaccggcc
     3301 tgttcttcgt ctgcaacggc gcggtgcggc tgatggtgag cgggcccgag ggcaaggaca
     3361 aggtcgtcga gctcttcgag cccggcggca tgttcggcga gatcggcgtg ttcaccggcg
     3421 cgcgctaccg tacctggacg caggcggtgg ggtcggtcgt gctgatacac gtgccgcgcg
     3481 agcgcgtgct ggccgcggtc gcgctggaca acgcgctctc caaccgcatg ctggtcgcgg
     3541 tgtgcgcgcg catccagcgc ctgatcgacg cgatcggcag caccgccggc ggcccggcgg
     3601 cggtccgcgt ggcgagctac ctgctggaac agctcgagcg cggtgcgcgc agcgacggct
     3661 gcatcatcct gccggcgccc aagaagacca tcgcctccct gctcaacctg acccccgaga
     3721 cgctctcgcg ggtgttgcgc aacctggtcg aggagggcgt gctcacggtg agcggccgcc
     3781 gcatccgggt gcgcaaccgt gcgcagctcg cccgcctgct gacgcacgac gaggcggttc
     3841 tacccctctg agctcaatgg ggctagtcac taagcactag tccagcccct cgtcgatacg
     3901 gcccatcccg tgcttttggc gaatggtgcg acgccacgcc cgagcctatc ctcaccccgg
     3961 aaaattcgtg accgtcggac ctttccggag cgcagtggga aatggctagt cgaaagtttc
     4021 agcagatgtc cgtgctcgtg atgagcacca ccgctttcac cgtctgtttt gccgtctgga
     4081 tgttgttcgc ggtgatcggc atcccgatca aggaagtcct cgcgctcaac gaaacccagt
     4141 tcggcctgct ggcggccacg ccggtgctga ccggctcgct gatccggctg ccgctcggca
     4201 tgctcaccga caagttcggc ggccgcatcg tcttcttcgt gctcatgcta tgcacggtgc
     4261 tgccgatcta tctcatcggc cacgccaccg aatactggca gttcctcgtc gccggcctct
     4321 tcgtcggctt cgcgggcggc tccttctcgg tgggcatcgc ctactgcgcg cgctggttcg
     4381 agcgccagaa ccagggcttc gcgatggggg tgttcggcgc cggcaactcg ggcgccgcgg
     4441 tcaccaagtt cgtcgccccc acgctggtgg tgatgttcgg ctggcagatg gtgccgcagg
     4501 tgtatgccgc ggcgatgctg atcaccgcga tcgcgttctg gttcttcacc tatgacgacc
     4561 ccgagcaccg ggtgcactcc tcggtgacct tccgcgacca gctgcgcgtg ctcaaggatc
     4621 cgcgcgtgtg gaagtactgc cagtactact cgatcgtgtt cggcggctac gtcggcctgt
     4681 cgctgtggct caccaagtac tacgtcaacg agttcggcat gggcatccag acggcggccc
     4741 tgctcgcggc ctgcttctcg ctgcccggcg gcgtactgcg cgcggtgggc ggctggctgt
     4801 ccgaccgcta cggcgcgcac aaggtcacct ggtgggtgat gtgggcgtcg tggatctgcc
     4861 tgttcctgct ctcctacccg aacaccgaat tcaccgtgca gacggtggag gggccgcgca
     4921 ccttcagcat ccacctcaac gtctgggtgt tcaccttcct gctcttcatc gtcggcatcg
     4981 ccttcgcctt cggcaaggcc tcggtgttca agtacatctc caacgagttc cccaaggaga
     5041 tcggcgcggt ctccggcatc gtcggcctgg tgggcggcat gggcggcttc ctgctgccga
     5101 tcatgttcgg cgccctggtc gacctcaccg gcgtgcgctc gagcgccttc atgctgctct
     5161 acggcgtgac ctgggtttcc ctgatctgga tgtacctgac ggaagtgcgt cgtgtcgaca
     5221 tgttcgacgg tcacgagacc gcggtcgact cgtccagggc ctgattcgca agacaacgag
     5281 gagtgggttt catgcaagca agcaatgtcg cggcgtcgag cccggcggtc accagcagcg
     5341 tcgacctcgt cgattggcgc cccgaggacg agaccttctg gaaggagaag ggctcgcgga
     5401 tcgccaaccg caacctgtgg atctccatcc ccagcctgct gtgcggcttc gccgtgtggc
     5461 tgatgtgggg gatcatcacg gtgcagatgg ccaacgcggg cttccccttc gcgcccgacc
     5521 agctcttctc gctcgccgcg atcgcgggtc tggcgggtgc caccacgcgc atcccggcgt
     5581 ccttcttcat ccgcatctgc ggcggacgca acacggtgtg gctgaccacc gccctgctga
     5641 tgatcccggc ggtgggcacc ggcatcgcgc tgcagagcct ggagacgccg ctgtgggtgt
     5701 tccagctcat ggcgctgctg tcgggcatgg gcggcggcaa cttcgcctgc tcgatggcca
     5761 acatctccac cttcttcccc aagcgcctgc agggcaccgc gctcggcctc aacgccggcc
     5821 tgggcaactt cggcgtgacc acctcgcagc tgctgattcc cgcggtgatg accatgggcg
     5881 tgttcggcgc gctcggcggc gacgcgatcc cgctggtcaa ggactcggcc acgctgatcg
     5941 gcaagatcgc cgccggcacg cccacctacg tgcagaacgc cggcttcgtg tggctgctgc
     6001 tgctggtgcc gctcgcggtc gtcggctggt tcggcatgaa caacctgctc accgtgtcgc
     6061 ccaacatcgg ctccaccggc gcggcgctgg gcaagatcat cctgttctac ggcatcgccc
     6121 tggtggtctc ggcgatcggc ctctacctct acctgccgag cgggctcggc gtgctggctg
     6181 gaggcgggat gtggatcatg ctgccgctgg tcatcctcgg caccctgtac ggcatgaagt
     6241 tcgccgccag cggcgagatg aagaccaacc tcgacaagca gttcgcgatc ttccgcaaca
     6301 agcacacctg gtcgatgacc gcgctctacg tggtgacctt cggctccttc atcggcttct
     6361 cgatggcgct gccgctgtcg atcacggtga tcttcggcaa cacccacgtc ctcgacccgg
     6421 ccacccaggc ctgggtgcat gcgaagaacc cgaacgcccc gtcggcgctg atgttcgcct
     6481 ggatcggccc cttcgtcggt gcgctgatcc gtccggtggg cggctggatc tcggacaagc
     6541 tgggcggctc gatcgtgacc cagtggatct cgatcgtgct cgtgatcgcc tccgcggtga
     6601 ccggctacgt gatgttcctg gcctaccact cggcgacgcc ggaagagtac ttcttcgtgt
     6661 tcatggccct gttcgtgctg ctgttcgcgg cctcgggcat cggcaacggc tcgaccttcc
     6721 gcaccgtcgg cttcgtgttc gacaaggacg aacgcggtcc ggtgctgggc tggacctcgg
     6781 cggtggcggc ctacggctcc ttcatcgccc cggtggtgat cggcggccag atcaaggccg
     6841 gcacgcccga atatgcgatg tacggcttcg cagttttcta cgcgctgtgc gtagtcctca
     6901 actggtggtt ctacctgcgc aaagacgcgt acatccagaa cccctgattc ccgcccgacc
     6961 gacggattcc cttttcaacc agacttttac cgatcgcgct tgatgaacga agcgacgact
     7021 tgagaggagc aaaccatgag tcattttctc gatcgcctga ggtttttcga caaggtcaag
     7081 gagaccttct cgaacggaca cggtatcgtc accaatgaag accgcaactg ggaggatgcc
     7141 taccgcaacc gctggcgcca cgacaaggtg gtgcgctcca cccacggtgt gaactgcacc
     7201 ggcggctgtt cctggaagat cttcgtcaag aacggactgg tgtcgttcga gatgcagcag
     7261 accgactacc cgcgcacccg cgaggacctg cccaaccacg agccgcgcgg ctgccagcgt
     7321 ggtgcctcgt tctcgtggta cctgtactcg ccgcaccgca tcaagtaccc gatgatccgc
     7381 ggccgtctgc tcgacctgta ccgcgccgag cgcaaggccg gtcgtgaccc ggtcgaggcc
     7441 tgggaggcga tccagaagga tcccgccaag cgcgagaagt acgtgcacgt gcgtggcctg
     7501 ggcggcttcg tgcgcaccag ctgggacgag gtcaccgaga tcgtcgccgc ggccaacgtg
     7561 tacacgatca agaagtgggg cccggaccgc atctacggct tctcgccgat tcccgcgatg
     7621 tcgatgatct cgtacgccgc cggtgcccgc tacctgtcgc tgatcggcgc cgcctgcggc
     7681 tcgttctacg actggtattg cgacctgccc gccgcgtcgc cgcagacctg gggcgagcag
     7741 accgacgtgc ccgaggccgc cgactggtac aactcgacct acctgatcat caccggcgcc
     7801 aacctgccga tgacccgtac ccccgacgcc cacttcgcca ccgaagtgcg ctacaagggc
     7861 accaagatcg tgtcgatggc gccggactac gccgagtacg tcaagttcgc cgacctgtgg
     7921 atgccggtca agcagggcac cgacgccgcc gccttcctgg ccatgggcca cgtcgcgctg
     7981 aaggagttcc tggtcgagaa gcaggacccg tacttcaccg agtacgcgcg caagtacacc
     8041 gacctgccga tgcaggtcgt gctgcgcaag tatggcgagg gctacgtgtc cgaccgcaac
     8101 ctgcgcgcgt ccgacttcga caacaacctc ggcgaggcca acaaccccga gtggaagacc
     8161 atcgtcttcg acaagaagag cggccgcttc atcgcgccga acggcacgat cggcttccgc
     8221 tggggcgagg agggcaagtg gaacctgctc gagaaggccg gtgccgacca ggccgagacc
     8281 gaggccgagc tcacctgcat gggcagccat gacgaggtcg tctcggtggg cttcccgcac
     8341 ttcgtgccgg gcgagcccgc actgctgtac cgcaacgtgc cggcccgccg cctgaagctc
     8401 gccaatggcg aagaggcctt cgtgacctcc gtgttcgaca tgcaggtcgc gcagtacggc
     8461 atcgaccgcg gtctgggcgg cggcaacgtg gcctcgtcct acgacgacgc caacgtcgcc
     8521 tacaccccgg cctgggctgc caagcagacc ggcgtcaagg ccgccgacct cgagcgcacc
     8581 ggccgcgagt tcgccgagaa cgcctccaag acccgcggtc gttccatggt catcatgggc
     8641 gcggcgatca accactggta ccacaacgac ctcgcctatc gcgcgatcat gaacctgctg
     8701 cacatgtgcg gctgcgtggg tcagaccggt ggcggctggg cgcactacgt gggtcaggag
     8761 aagctgcgtc cgcaggccgg ctgggcgccg atcgcgttcg cgctcgactg gcagcgtccg
     8821 ccgcgccaca tgaactcgac ctcgttctgg tacttccaca ccgaccagtg gcgctacgag
     8881 acggtggacg ccgactcgct gctgtcgccg gccggcccct gccgcaacaa gggctcctcg
     8941 ctcgccgact acaacgtcaa ggccgtgcgc atgggctggc tgccgtccgc cccgcacttc
     9001 aaccgcaacc cgatcgagct ggccgaggag gcggcgcgtg ccggagcgac cgacgaggcg
     9061 agcgtgtcga agtacgtggt cgaccagctc aagtcgggcg cgctcgacgt ctccttcgcc
     9121 gacccggacg ccgaggagaa ctggccgcgc aacctgatcg tgtggcgtgc caacctgatc
     9181 ggctcgtcgg ccaagggcca cgagtacttc ctcaagcacc tgctgggcgc gcagaacggc
     9241 gtgatgcagg aaggcggcgc gggcaacaac tgcaaggaag tgaagtggcg cgagcacggc
     9301 cccaccggca agctcgacct gatggtggac gtcaacttcc gcctcaactc gaccggtgcc
     9361 tattcggaca tcatcctgcc gaccgcgacc tggtacgaga agaacgacct caacaccacc
     9421 gacatgcacc ccttcatcca cccgctgggt gaggcggtga cgccgggctg ggagtcgaag
     9481 tccgactggc agatcttccg cacgctggcg aagaccttca ccgcgctcgg cgccaagcac
     9541 ctcggcaccc gcaaggacgt ggtctcgctg ccgatgcagc acgactcgcc gaccgagctc
     9601 gccaccccga tgggcgtcgg caaggactgg aagcacggcg agtgcgagcc catcccgggc
     9661 aagaccatgc cgatgctcaa gctcgtcgag cgcgactatg gccagatcta caacaagtac
     9721 atcgcgctcg gcccgctgat ggtcaagctg gggaacaacg tcaagggcct cgactgggac
     9781 accacccagg aatacgaaga gctcaagaag tgcaactacc cggtgcaggt cgagggcgtc
     9841 tcgaagggca tgccttcgct cgaggaagac atctacgtct gcgactcggt catgcgcatg
     9901 gcgcccgaga ccaacggcga ggtggcacac aagtcgtgga gcgcgctgtc gaagaagacc
     9961 ggcatcgacc accaccacct gtatgccggc cgccacgagg acaagatcac cttccgcgac
    10021 atcgtcgccc agccgcgcaa gatcatcacc gcgcccacct ggtccggcat cgagtcggag
    10081 accgtgtcct acaccgcggg ctacaccaac atccacgagc acatcccgtt ccgtaccctg
    10141 accggccgtg cgcacttcta ccaggaccac gagtggttcc tcgacttcgg cgaaggcttc
    10201 tgcacctaca agccgccggt cgacctcaag gcccacgaga aggtgcccga cagcgtgcgc
    10261 aacaagccgc acctgaccct gtcgtggatc accccgcact ccaagtgggg catccactcc
    10321 agctaccagg acaacctgcg catgctgaac ctgttccgcg gtggcccgta cgtgtggctg
    10381 tccgaggaag aggccgcgac catcggcatc aaggacaacg actgggtcga ggcgatcaac
    10441 gccaacggcg ccacggtggc ccgcgcggtg gtctcgcagc gcatcccgcg tggcatggcg
    10501 atcatgtacc acgcccagga aaagaacgtg aacgtgcccg gctcgaacac caccggcaag
    10561 cgtggcggca tcctgaactc ggtcacccgc gtcatcgtca agcccaccaa catggtcggc
    10621 ggctatgcgc aactggccta cagcttcaac tactacggca ccgtcggttg ccagcgtgac
    10681 gaagtcgtgg tcatccacaa gatcgaggac caggacatcg actggctgga gcgtccgctc
    10741 acgcccgaac gcgaagccca gcgcaacccc gtgggcatcg gcaagaagta agcgccgact
    10801 cgagaccaga gattcaggag aaacaaatga aaatccgcgc gcaattcgcg atggtgttca
    10861 acctcgacaa gtgcatcggt tgccacacct gctccgtgac ctgcaagaac gtgtggacca
    10921 accgcaaggg cgtcgagtac gcctggttca acaacgtcga gtccaagccc ggcatcggtt
    10981 acccgaagga gtgggagaac caggacaagt ggaagggcgg ctggaccaag ctcaatggca
    11041 agctcgagct caaggccggc ggtcgtctga agaagatcgt gcagatcttc tccaacccga
    11101 acctgcccga gatcgacgac tactacgagc ccttcaccta cgactacgcc cgtctgcaga
    11161 acgcgccgct gtccgaggcc gcgccgaccg cgcgtccggt ctcgcagatc accggcgaga
    11221 agatggacaa gatcacctgg ggcccgaact gggaagacga cctcgccggc gagttcgcct
    11281 cccgtgctcg tgacaagaac ttctccaaca tggagaagga aatgtacaag cagttcgaaa
    11341 acaccttcca catgtacctg ccgcgtatct gcaaccactg catcaacccg gcgtgcgtgg
    11401 cctcgtgccc gtccggcgcg ctctacaagc gcgaggaaga cggcatcgtg ctcgccgacc
    11461 aggaccgctg ccgcggctgg cggatgtgca tctcgggctg cccgtacaag aaggtgttct
    11521 tcaactggga gtcgtccaag gccgagaagt gcgtgggctg ctacccgcgc gtcgagaacg
    11581 gcatgccgac cgtctgttcc gagtcctgcg tgggtcgcat ccgctacaac ggcatcatcc
    11641 tgtacgacgc cgacaaggtc tcggccgcgg ccagcgccga caacgtccag gacctgtacc
    11701 aggagcacct ggacatgttc gtcgatccct tcgacccggc cgtgatcgag caggccaaga
    11761 aggacggcat caccgacgac tggatcctcg ccgcgcagaa atcgccgatc tacaagatgg
    11821 ccgtgcagtg gaagatcgcc ttcccgctgc accccgagta ccgcacgctg ccgatgatct
    11881 ggtacgtgcc gccgctctcg ccggtgcagt cgcagatcga ccagaaggcg ctgccgaccg
    11941 aggccgacgg cgtgatcccg aaggcttccg cgatgcgcct gccggtcaag tacctggcca
    12001 acctgatgac cgccggcaag gagcagccga tcgtcgacgc gctcaaccgc atgatcgcga
    12061 tgcgctccta ccagcgctcg gtgcacgtcg agggcacgcc cgacacgcgc gcgctcgacg
    12121 cggtgggcat gaccgaggac atggccaagg agatgtatcg ctacctggcg atcgcgaact
    12181 acgaagaccg cttcgtgatc ccgacctcca aggaagagat gcgcctcgag gactaccacg
    12241 gcttccaggg ccaggccggc ttcagcttcg gcagcgcctc gtcggtcggc atctcgccga
    12301 actcgctgtt ccccgagcgc cgcaaggagt cgatggagcc gcgcaagccg gtcccgcacg
    12361 ccgacgagat gcacgacgtc accggcgaac gctactgagg agactgaacc atgcagacct
    12421 acaagctgct tgccgtgctg ctcgactacc cgggcagcga gatcgtcggc gacctgcgcg
    12481 ccgcggtctc ggagcagggc ggcgcgcggg gtctggtgcg ctcggtggac accgacaagg
    12541 tgttcaccga ggctgagcac gagagcatcg ccggtttcat cgactggatg ctcgctcagg
    12601 accagaccga gctcgaaggc cgtttcgtca agaccttcga cctcactccc gagcacagcc
    12661 tgcacctgac acaccacgtg ttcggcgacg acaagaaccg tggtccggcg ctgatcgacc
    12721 tgtcggagtt ctacaagtcc tacggactgc agcacgacga acacgagatc ccggactacc
    12781 tgccgatgat gatggagttc gtgtcgcaac tcgaggagac cgaggcgcgc gtgttcctga
    12841 ccgacgcggt gaaggtgttc aacgtgctcg cgaccaacct ggaaaaggcg gagagcccct
    12901 atgcggcgct cgttcgcgtg atcgaaaacc acagctcgct ggcccgcatg gccgcctgag
    12961 gagaagacga tgtccctgac caacctgatt ttcggggtct atccctacat tgcgctgacc
    13021 gtgttcgtga tcggcagctg gatccgttac gacaacgagc agtacacctg gaagaccgat
    13081 tcgtcgcagc tgctgtccaa gcagggcatg atgctggcga gcaacctgtt ccacgtcggc
    13141 atcatcatga tcttcttcgg ccacttcgct ggtctcgtgc tgccgcacgg gctctggctc
    13201 ggcctgggga tctccgacct ggcgcaccag tggatcgcca tcatcgccgg cgtgatcttc
    13261 ggcatcatgt gcctggtcgg tggctccatg ctgtggtatc gccgcatgta caacccgcgc
    13321 gtgcgcatca acagccgtcg cagcgacgtg ttcatcatca cctggctgat ggccacgctg
    13381 atcctcggcc tgctgaccgt gccgttctcg atcggtcacg ccgccaaggg tgatccggcc
    13441 gtgatgcttg cgctggccga gtgggtcaag agcatcctgc tgctgaaccc gcaacccgag
    13501 ctgatgacca aggtcgatcc gatcttccgt gcgcacatct tcttcggcat gacggtgttc
    13561 ctggtgttcc ccttcacccg cctggtgcac atcctgaccg cgccgttcag ctacctgacg
    13621 cgcgcctacc agatcgtccg gaccaagcgc cgcctggcct gaggctgaag cgaagggcag
    13681 ggcgggcggc cgacacggcc gccggccttg cctttcgacc tttttgcccc tagcttgcgc
    13741 ggatgcgcaa gaaagcaccg attctcatgt tcatccgcag ctcgggcctg tcggtcaaga
    13801 tcaccggcat gctgctcggc ttcttcctcg tggcgctcgc cgcgatcgcg ctgaccctgt
    13861 tcatctcctg gcacctggag ggcgcggcgg cggcgatcaa cgatgccggc agcctgcgca
    13921 tgcgggtgta ccgcctcgct catcacctcg cgcgcgccga cgtcgagaag atcgaccgca
    13981 gcgcgttcgc cgccgacctg caggagcgga tcgatgattt cgacgccgtc ctctccgtgc
    14041 tgcgccgcgg agatccctca cggccgctgt tcgtgccacg cgaggacggc atccccgaag
    14101 acctggcgaa gatggccgac aactgggcga cgcgcagccg cccgatcctg agcgcgatcg
    14161 tcgccgaccc gagcccgcag aacctgcacc tgcgcgggct cgagttcgat gccgccgccg
    14221 aggcctgcgt cgactcgatc aatcaactcg tgctgcgcat ggagcagagc tacgcgcgca
    14281 acaccaacat cctgcgcacc tcgcaggtca tcctgatcgc gctcgcagtg atcggcacga
    14341 tcctgctgct gcgcttcttc ttcctcaccg tgatccgccc cgtattcgag ctccacgagg
    14401 gcgtcaagcg catgggccag gaagatttcg acgcccgcgt gccggtattg tccaaggacg
    14461 agttcggcga gctctcggcc ggcttcaatc gcatggccgc ccacctgcag agcgtctacg
    14521 acacgctcga ggagcgcgtc gcggccaaga cgcgcagcct ggaagagaag aaccgcgagc
    14581 tcgagatcct ttacgacatc gtcgccttcc tgcgcgagcc caacgacgtc gatacgctgt
    14641 gcaagggctt cctcgagcgc gtgcagaaga cgctgggtgc gagcgcgagt tcggcgcgcc
    14701 tgctcgacct cgagtctcgc aacctgtgca tgatcgttca cgacgggctg ggcgaggact
    14761 tcctcgatcg cgaggaggtc ctcgcctgcg gcgaatgcgt gtgcggcgag gcggcgcagg
    14821 gcagcgggtt gtcgctgacc ctggacgtgc gcaacgcctc actcgcggtc acccgcgatg
    14881 cctgcctgcg cgccggcttc cgcacggtct cggcgacctc gatcaccgcc aacaagcgcg
    14941 cgctcggcgt gttcaacctg tacttcgatc attcgcagcc gatcggcgac gccgaccgcc
    15001 agctcctcga gacgctcggt cagcagctcg gcatcgcgat cgagaaccag cgcctgcatg
    15061 cacgcgagcg tgagctcgcg gtctcggagg agcgcaacct gctcgcgcgc gagctgcacg
    15121 attcgatcgc gcagggcctg gccttcctga acctgcaggt gcagatgctc gagcgcgcgc
    15181 tcgccgagca gcgcgccgag gacgtgcgca cgacggtgga gatgttgcgc cgcggcatcc
    15241 aggagagcta cgaggacgtg cgcgagctgc tggtgcattt ccgcacccgg gtcgagcagc
    15301 aggacctcga tgccgcgatc gcggcggcgc tgcgccggct cgcggagcag acgggcatcg
    15361 ccaccgatct cgacgtacag ggcgacggcg cgccgctcga tcccgaggcc gagacccagg
    15421 tgctctacat cgtccaggag gcgctgtcca acgtgcgcaa gcacgccggc gccggcacgg
    15481 tgtcggtgag cgtgcgccgc ggccgcgacg gactggcggt gacggtgcgc gacgacgggg
    15541 tcggctttgc cgaggatcgt gacaccaccg acggcgaggc gcacatcggg ctgcagatca
    15601 tgcgtgaacg cgcgctgcgg atcggcggac gtttcgcggt gcgctcctcg cccgggcgcg
    15661 gcaccgagat ccgcctggag ctgccgcgaa ccaacgaggt ggaagcctga tgaccgaagc
    15721 caagatccgc gtcctgctgg tggacgatca caccctgttc cgcagcggca tccgttcctt
    15781 gctgcagagc tacgcctgct tcgaggtggt gggcgaggcc ggcgacgggc gcgagggcat
    15841 ccgcctcgcc ggccagctgc ggccggacgt ggtgctgctc gacaacaaca tgcccgggct
    15901 ctccggccgc gaggctgccc gcctgatgct cgaggaggct ccggagacgc gcgtgctgat
    15961 gctgaccgtc tcggaggatg cggacgacct catcgagacg ctgcgcgcgg gggcctgtgg
    16021 ctacctgctg aagaacatcc aggccgagac cctggtgtcc gcgatcaaga cggcggcgca
    16081 gggagagtcg gtggtgtcgc cacagatgat gggcaagctc ttgagcggcg tgcgcggcac
    16141 cccgggcagg gcggcgagcg gcgggctccc gcctgcgccg gcgccgcagg ggaggagcac
    16201 gtccgtcacc ggggccgaag ccgccgaact ggacaagctg tcgccgcgcg aacgcgagat
    16261 cctgcaattc atcgcacgcg ggcagagcaa caaggagatc gcgcgcgcac tcgagctcgc
    16321 cgagagcacg gtgaagatcc atgtgcagaa catgctgcgc aagctcaacc tgagcagccg
    16381 cgtgcaggcg gcggtgttcg cggtggagaa gggcctgggg caggggccgg agacctgagg
    16441 ctcggcgccg caggtcggcg gtcgcgcccc gggctcagcg cagctgtgag gcgaggtcgc
    16501 ggaacacgcc gccgagcagc ttgacttcct cgcgatggtg cagtgcgatc gtctcggcca
    16561 ggcgttcgcc ttcggccgtg aggtgcacct cgaccgcgcg ccgatcctcg cgccctgggc
    16621 gacgctcgac cagccccagc ttctcacagc gcgagaccag cgacaccaca ccgtgctgat
    16681 gagcctgcag gcgctcggcg agctcgccga tgcaggccca ttcgcgtccg ggatagccct
    16741 tgacctggag cagcagcagg tattgaaggt tggtgatgcc gtgacgccgg gtgagcagct
    16801 cggagaagcg caggaagcgg cgcaactggt agcggaaatc ggcgagggcc tcgaattcgg
    16861 acttgtcgag tggagtgttc atcgtgtgcg gattttatct tcttccgccg ttgcttcggc
    16921 agcccgatcg cgagatcgtg cttgcaatcc ggcgcttggg gattaatatc aaatcgtgat
    16981 gtaaaaaaag agcggccgcc gattcgaaca gatccacaag gtggcggccg gattcccacc
    17041 cgaaagagga gaccgaatca tggacgtgat gcaatttccc cgtatggtcg tttcgagccg
    17101 agacggctgg gatctggtcg cgcaggcgcg gcccccgatg gactggctgt tccgtcgcct
    17161 ggtgctgccg atgtccctgc tgccgccgct gatgatcctg cttgcttcgg ggggcgtggg
    17221 cgagcgcgtg ttccccgagg cgggtttcgg caactggctg atcgccgcgg tgctgttctt
    17281 cgtggccgag catttcagcg tgccgatcat ggcgaactcg atccgccagg cctcgatggc
    17341 caaggacggc agcaatcggc tcgaggatgc ctacgcggtg gcggcgatcg cgccggtgcc
    17401 gctgtggttg tcctcgctcg cggtggtgtt cggcagcgcg tggttcgtgg tgctcgtcgg
    17461 cctcgtcgcg ctcggcgcct cggccatgct catccgccac ggcgtcgatc gcctgctcgg
    17521 catcgaggag gacgtcgagg cgagcgaggt ggcgatgcag gtcaccagct tcggcgtgct
    17581 gacctggctg gtgctgctct cgatcgccgc gggcgcggtg atgctgctgt gaggcgcctc
    17641 ggtacgctca ggccttgacc cgcatcaggc gctgcttctc gcgctcccag tccttcttct
    17701 tctcgtcttc gcgcttgtcg tgcagcttct tgcccttggc gagcccgatc tcgagcttga
    17761 tcagcccttt cttgtagtgc aggtcgagcg gcaccagcgt atagccggcg cgctcgacct
    17821 tgccgatcag gcgggcgatt tccttcttgt gcagcagcag cttgcgcgtg cgcgtggggt
    17881 cgtggcgcac gtggctggac gcggtggtga gcggggtgat gtgcatgccg aagaggaaga
    17941 tctcctcgcc acggatcacc acgtaggatt ccttgatgtt cgagcgaccg gcgcggatcg
    18001 ccttgacctc ccagccttcg aggacgatgc cggcttcgtg cttctcctcg atgaagtagt
    18061 cgtgaaaggc cttgcggttt tcgatgatgc tcatggttgg gcgtctcgtg gcggcgcggc
    18121 cctgagccgg cgcatccgta tgcggtagaa tcgcggattt taacagttcg gccgcacctc
    18181 cgttccgtcg tggtggtgcc gcccgcgacc ttgcccatgg ccgaagtcaa taagctcgtc
    18241 ctgatagagt tcacccccga gcagatgttc gagctcgtcg atcgctgcga ggagtacccg
    18301 ctgttcctgc cctggtgcgg cggcaccgaa ttgatcgagc gtaccgagac gatcaccgcc
    18361 gcgacgctgc acatcaacta ccacggcatc aaggcgcact tcagcaccga gaacacgaag
    18421 cgctacccgc aggagatgaa gctgcgcctg accgatgggc ccttcaccca tctcgatggc
    18481 ctctggcgct tcaccgcgct cggcgacacg gcgtgcaagg tcgagttcca gctgcgctac
    18541 cagttcgcga gcaagctgct ggaaaaggtg ctcgggccgg tgttcaacca catcgcgaac
    18601 actttcgtcg attccttcgt caagcgtgcc ggccaggtct accgggcagg gcaggggagt
    18661 gcagcatgag cgggttgatc aacgtggaag tggtgtacgc gctgccgcag cgccaggagc
    18721 tggtgcatgt gcgtctcgcc gagggggcga cggtgcgcga cgcgctcgag gcgtccggcc
    18781 tgttgcagaa atatcccgac atccagcccg accgcgccaa caagctgggc gtgtatgcga
    18841 agctggtcaa gctcgacacc gaggtgcgcg accgtgaccg ggtggagatc tatcgcccct
    18901 tgatcgccga tccgaaggcg gtgcgcaaga agcgcgccga cgaaggcaag gtcatgaaaa
    18961 agggcggggg accggccgaa gcggccgagt gaagcgtcgt cgctgcaggg agcccggcgc
    19021 ggtgcgcgcc cggccgtaga tggcggaagc ggcctttcga ggggggcgtc cagcgcctac
    19081 ctgcagcgtt cggcgatctg gcgctccagt cgtgccatct gctccgcgcg cgcctggtcg
    19141 tcgaggaact cgcgttcgcc cctggcgttg aagcggacca tgcgctggcc ggcgcgcagg
    19201 gcagcgagtt cgtgctgggc gctcgtgcag aagcgttgcg tctcgtctct agccgcagcc
    19261 tcctcggcgc gcttggcttc ggcttccgct tcggcggcgc ggcgctcctg gaaggcctgc
    19321 tcgcgttcgg tgagcgaacg cggtgacgag ggcgaaacgc tgggctgcgg gtctgcagcg
    19381 ctgctcgcct cgccactcgg gcgtgcgggc ggggcgccgc ggagcaaggt cgcctcgacg
    19441 gccgcgggcg gcatgtcgcc gtagtgcgtg cgtccgtcct tgtccttcca gctgtacacc
    19501 tgggcgcaag cggggagagc gttcagcagc agggccagga tcgccaccgg ggcgagtcga
    19561 cggttcatcg gcacaattct ccgcggcgag ccgcttacgt ggtgcaggag cgctctgtat
    19621 aatacggatt tggtcgaaag gaaaaaagcc atgcgagtga tccagaaggc gctgaccttc
    19681 gatgacgtcc ttctcgttcc cgcccactcc acggtcctcc cgcgcgacgt tagcctgcag
    19741 agccaggtta cgcgccgcat ccgcctgaac gtcccgctcg tctcggccgc catggacacg
    19801 gtgaccgaga gccgccttgc gatcgcgctc gcgcaggagg gtggcatcgg cgtggtgcac
    19861 aagaacctca ccccggcgca gcaggccggt gaagtgcaca aggtcaagcg ccacgagtcg
    19921 ggcatcctca aggatcccat caccatcccg ccgacgatga ccgtcggcca ggtgatcgcg
    19981 ctgcagcgcc agaaccgctt ttccggcgtg ccggtggtcg agggcggcaa ggtcgtcggc
    20041 atcgtcacca accgcgacac ccgtttcgag accaatctcg accagctcgt ctccgagatc
    20101 atgaccccgc aggaccgcct cgtcaccgtt cgcgagggtg ccagcctcga ggaggcacgc
    20161 gagctgctgc gcgtgcaccg cctcgagcgt gtgctcgtgc tcaacgaggc cggcgagctg
    20221 tgcggcctca tcacggtcaa ggacatgatg aaatccaccg agcacccgct cgccgccaag
    20281 gacgagcagg gtcgcctgcg cgtggccgcc gcgatcggcg tgggcgccgg caccgaagag
    20341 cgcgccgagc gtctcgccga cgcaggcgtg gacatgatcg tggtcgacac cgcccacggc
    20401 cactcgcaag gcgtgctcga ccgtgtcacg tgggtcaaga agcacttccc ccacatcgag
    20461 gtggtcggcg gcaacatcgc caccgccgac gccgcgcgcg cgctggtcga tgccggcgcc
    20521 gacggcgtca aggtcggcat cggcccaggc tcgatctgca ccacccgcat cgtcgccggc
    20581 gtgggcgtgc cgcagatcag cgcgatcgac aatgtcgcca acgcgctggc gggtacgggc
    20641 gtgccgatga tcgccgacgg cggcatccgc ttctcgggcg acatcgccaa ggcgatcgcc
    20701 gcgggcgcca acgtggtcat gctcggcggg ctgttcgccg gcaccgagga ggcgccgggc
    20761 gagacggtgc tgttccaggg gcgctcctac aagtcgtacc gcggcatggg ttcgctcggt
    20821 gcgatggaga agggcgcggc cgaccgctac ttccaggaag agaacaccgg caacatcgac
    20881 aagctcgtgc ccgagggcat cgagggccgc gtgccctaca agggctcggt cacggcggtg
    20941 atccaccagc tcgtcggcgg cctgcgcgcc tcgatgggat acctgggttg cgccgacatc
    21001 ccgagcgtgc acgcgcgtgc cgagttcgtg cagatcagct cggcgggcat gcgcgagtcg
    21061 catgtgcacg acgtgcagat caccaaggaa gcgcccaact accagatcag ctgagcgcgc
    21121 tccttccaga catccgggcg gctgcgaggc cgcccttcct ttttcgacgt tcgagatttc
    21181 cgccccatgg cccaccagaa gatcctcatc ctcgatttcg gctcccaggt ttcccagctc
    21241 atcgcgcgcc gcgtgcgcga gcagcaggtg tactgcgagc tgcatccctt cgacgtctcg
    21301 gacgagttcg tgcgcagttt cggcgcccag ggcgtgatcc tctccggtgg ccccaactcg
    21361 gtgtacgagg ccgaggactg gcgcgcgccg caggcggtgt tcgagctcgg ggtgccggtc
    21421 ctgggcatct gctacggcat gcagaccatg gccagccagc tcggcggcaa ggtcgagagc
    21481 tcggccaagc gcgagttcgg ctacgccgag atgcgcgcgc gcggacattc gaagctgttc
    21541 accggcatcg aggatcgcac caatgccgaa ggccacggcc tgctcgacgt gtggatgagc
    21601 cacggcgaca aggtcaccgg gttgccgccg ggcttcaagg tcatcggcag caacgagtcc
    21661 accccgatcg cggccatggc cgacgaggcg cgtggcttct acggcgtgca gttccatccc
    21721 gaggtcacgc acacgatcaa gggacgcgag atgatcgcgc gcttcgtgca cgacatctgc
    21781 ggctgcggcc acgactggaa catgcccgac tacatcgagg aggcggtgca gaagatccgc
    21841 gagcaggtcg gcgacgaaga ggtcatcctg ggcctgtcgg gcggagtcga ttcgtcggtc
    21901 gcggcggcgc tgatccatcg cgcgatcggc gaccagctca cctgcgtgtt cgtcgatcac
    21961 ggcctgctgc gcctcaacga gggcaagctg gtcatggaaa tgttcgccgg ccgcctccac
    22021 gccaaggtcg tgcatgtcga cgccaccgag cagttcatgg gccacctcaa gggtgtcacc
    22081 gaccccgagc agaagcgcaa gatcatcggt cgcgagttcg tcgaggtctt ccaggccgag
    22141 gccaggaagc tgccgaacgc gaagtggctg gcccagggca cgatctaccc cgacgtgatc
    22201 gagtccggcg gcgccaagag caagaaggcg cacaccatca agagccacca caacgtcggc
    22261 ggcctgcccg agacgttggg cttgaagctg ctcgagccgc tgcgcgacct gttcaaggac
    22321 gaggtgcgcg agctcggcgt ggcgctcggt ctgccgcacg acatggtgta tcgccacccc
    22381 ttcccggggc cgggtctggg cgtgcgcatc ctcggtgagg ttcgccagga cttcgccgac
    22441 ctgttgcgcc gcgccgatgc gatcttcatc gacgaactgc gcgccgccga ctggtacgac
    22501 aagaccagcc aggccttcgc ggtcttcctt ccggtcaaga gcgtcggcgt gatgggcgac
    22561 ggccgcacct acgaatatgt ggtggcgctg cgcgccgtgc agacgcagga cttcatgacc
    22621 gcgcactggg ccgagctgcc gcacagcctg ctcggcaagg tgagcaaccg catcatcaac
    22681 gaggtgcgcg gcatcaaccg cgtggtgtac gacatctcgg gcaagccgcc ggcgacgatc
    22741 gagtgggagt gatcgaccgg gcctgacgcc ctggagtcaa agcctgacgc ctgaggacgt
    22801 cgggcttttt tgtgtcgggc gcctcggcgg cggcccgcgc cgtcctgctc cgccggcgcg
    22861 gtcgatgcgg ccgtggtcgc ctgcagcccc cctccgccga tcaggccgct gcaccgagcc
    22921 gatcctctgc ccactgcatc acctgctcgg aggggacctc ggcgcagcgg ccgcacagcg
    22981 tgtggctggc gaggcgtgcg cgcgtgagcg agggggaggg gaggccacac agcaagcgcg
    23041 cgacggcccg gggcgaggcc agcgcctggc ccgtgcccgc acgcagcgcg ccgagttcga
    23101 cggcgagggt ctcggggatc gccgacgtgc cgcgctcgca taccgaggcg gccaggccct
    23161 ggcagccggt gcattggccg cagggctggg gcaggatctc gccgaggtgg gcggcgagtg
    23221 ctgcgctgtg gcaagccgac agcccggcag agtcgaggac ctgcatcagc cgcgcgtgct
    23281 cggccttctc gcgctccaac atccgtcggt gcagcgcggt ggcgagggcc tcgcggtcgt
    23341 cgggcgcgcg cagaagccgg tagcggtggc gcaccccggt caccttcact ttcagcatgg
    23401 cctgttcgcc cagccagtcg agcgcgcgca ccacccgctc gcgctcgcac ccgaggaccc
    23461 gcgcagctgc ggcgggatcg atgcggaacc agagccgctc cttgaccgcg aggcggagca
    23521 gatgcgcgag gaaatgccgg cgctcgccgt cgaagcgggc gaggatctgc gccgagctca
    23581 tgagcggctt gaagcggtag tcggcgtaga agggcgtgcc gccctcgagg aagccatcga
    23641 gctcgaggta ggtgagcagc gtgcgcagca ccagcaggcg caggtcgtgg cgtgcggcca
    23701 ggtcggtgag cgcgagctcg agctcgctcc ctgcctcggc gaagcgttcg tcggggaggc
    23761 tgcccaacgc cgccttgtcg ggcgtgtcgc agtggatgaa gtcttccagc acgttgacgt
    23821 cgcggatgac gagcagcagg tggcaggtcg agggcctgcc gtcgcgtccg gcgcggccga
    23881 tctcctgggc gtagttctcc aggctcttgg gcaggttgta gtggtagacg cagcggatgt
    23941 cggccttgtc cacgcccatg ccgaacgcga tcgtcgccac cacgatggcg cggtccgagg
    24001 ccatgaacca ctcctgcacc gcagcgcgct cgtcgtcctt catgccggtg tggtaggcgc
    24061 gcgccggcca cgccgcggcg gcgagggtgg cggcaagcgt ctcggcggtc ttctgcaggc
    24121 tgacgtagac gatggtcggg ccgggggcac gctgtgccag caggccgagc agggtgtcgc
    24181 cgcgtcggcc ggcatcgacc gcggagacga gcagctgcag gttcgggcgg tagaagccgg
    24241 agcgctcggg ggcaacgtgg cgcaggcgca ggctgccgtc gcgcaaggcc gccatcaggg
    24301 cgcggtgttc gttggtgccc agggtcgagt cgaactgggc cgctgcgatg ccgcgcgcgg
    24361 ccagcccatc gatcgggtcc ttcatcagcg cgatcagggg ggagaccaac acggtcacac
    24421 cggcagcggc gccggcagct gatcgcacag ggacttgcca ccgcccgtgg ggaatacggc
    24481 cgcggccgat ctgcccgcca tgaggtgctc gatcaccgcc tgctggccgg ggcggaagcg
    24541 gctgtggccg aagtggtgct gcagcgcgct gaggatcggc tcggatgtgc tcatagggga
    24601 tgacgttgcg aagctgcgag gcgtcgcacc agtaacggga tatgctcgat caagaatgac
    24661 aaggacattg gcacaagggc cccttgggtg cgtggaggct tgcggccacg gcgatcgagg
    24721 taagatccgg ccatgaacga actccgcccc cgcctgtttc gcgactggtc cgcgatcgtc
    24781 cgcaccaccg tcaagctgtg gctggaagcc caggtcttcg tgcacgccgc ggcgctcgcc
    24841 ttcttcaccg tgttctcggt cgcgccggtg gtcatcgtgg cggtcaccgt ggtcggcctg
    24901 gtgctcggcg agagcgcggc cgagggacgg atcgcggagc agctcgaggt ggcgatcggg
    24961 ccggaggcgg ccgcgacgat ccagaccgcg gtgcagaaca gccgcatcca gcatagcggg
    25021 ctgctgccca ccgtcgccgg tttcgccgcg atgctgtttg gtgcgaccac ggtgtttacg
    25081 cagatgcaga acgcgctcaa cgccatctgg ggagtggcgc cgcgacccac gcgcagcagc
    25141 gtgttcatct atctcaagac ccgcctgctc tcgctcgccg tggtgctcgg catcggcttg
    25201 gtgctgctgg tctcgttgtc gctgagcatc ttcgtgcgcg cgctcgtcgc cttcgcgcag
    25261 gactggctgc cggtgccggt gggcttgatc atcgggctgg actgggcgat cgcgctgctg
    25321 gtggtcacgc tgctcttcgc gaccatcttc cgcgtgctgc ccgacgtggt gctgcgctgg
    25381 cgcgacgtgc tgccgggcgc cttcgtcacc gcgctgctgt tcgccctcgg gcgcgcgctg
    25441 atcgctatct acctgtcgac caccgcgacc gcgtccacct acggcgcggc gggctcgctg
    25501 gtgctgctgt tgctgtgggt gaattattcc tcgctgatcc tgctcttcgg cgccgccttc
    25561 acccgcgcct acctcgaggc gtgcggttgt gccgtgcgcc cgcgcgccac ggcggtgctg
    25621 gtgcatcggc agctgatcga ggattgaccg cggccgcggc gcgcggcgca gcgacgttca
    25681 gttgcgcagc agctgcagct tgaagtgctg ctggatgaag gactggaagc tggcgacgcc
    25741 ctcgaaggcg aggcgcagtt cgccttgctg catcgcgttc agctggtcga gcgcgatgta
    25801 gttgcccggc ttgcgccctg cgcgcagggc ctcgacctgg ccgcgcaggc gcatccgcac
    25861 gaggaagtcg aaggctgcgc gcaggtcggc gacctgttcc gccttgagca cgccggcctc
    25921 gatgagcgcc tccatgcggt cgtgcgtgct gccgtcgagc cggcgcgcct ccatcgccag
    25981 cgccttgatg ccgtcggtga tggcgaagat cccggccttc ttgaggtcga cctcgccgcg
    26041 gtgctcgccg gacttgtcca ccttgatgcg gccgaaccag cccagcggcg gcgcgaagtt
    26101 gaccatgttc tgcgccatgc gcacgaggaa gccctgttcg tggctcatgt agtgcagcgc
    26161 gtgctcgcgc agggtgtcgg cgagctcgcg ccgaccgtag agcgggcgca ggtccatgaa
    26221 catgctgccg gtcatcacgt tctcgggcgt cggcgcggac agccactgcg tgagctcgcg
    26281 cttccaggcc gtgaggctgc gccgccaggc cggattgcgc gccatgatgc caccggggca
    26341 gggcggcacg ccgatcgaga tcagggcctc gatgagctcg tgggagaagg cctcgagccg
    26401 ggccagctcc tcgccctgca ccgagtcggc gtagaggatc gcgttgtcct ggtcggtgga
    26461 gagcgtctgc tcgccgcgcc cctcgctgcc catcaccacg aaggcgaaat ccgcggtgag
    26521 gtccgggtag cggtcgcggc gcagcaggtc gatgaggcgg atcagcacct ggtcgttgag
    26581 gttggcgatc agcttcacgg tgtcgcgtat cgcgatgccg gtgccggcga ggtgcacgat
    26641 cagcttctgg atgcgctggt ggagctcgcg cagtgcatcg atcgagtccg ccttctcgat
    26701 gtcgagcacg agctggtggg gcgagtgcgc ctgcaggcgc agcaggtcgg tgacggtgac
    26761 gatgccggcg agcgcaccct tgcggtcgac caccaccagg cgatggatgc cgtggcgcga
    26821 catgcggtag agcgcctcgt agagtacgtc ttcctcgccg atggtgatca ccggcgcgct
    26881 catcacgtcg cgcaccctga gccccgccgg gtcgcggccg gcggcgatca ccttgttgcg
    26941 caggtcgcgg tcggtgagga tcgcggtcgg gcgctcgccc tcgacgacga ccacgcagga
    27001 gatgctcatc tcgcgcatgc ggccgacgat gtcgaccagc acgtcgtcgg cgccgcagct
    27061 caccacgcgg cgctgctcga tgtcccggat cggacgaaag aactcgtttt cttctgccat
    27121 ggctgctccc ggggacgcat cgaatgcgtc attttacccg ggcgcggccg cttcagcccg
    27181 tcgccgcggc tgcaagcacc aaaccgggat cgagcgcgac cacctcaccc accatgatca
    27241 gcgccggcgc gcggatgccc gccgcgcgta ccgctccggg cagggtcgcg agcgtggcgt
    27301 ggacgccgca ctggcgcggc gtggtggcgg cgtggatcac cgccgccggc gtgtccgccg
    27361 cgaggccgtg cgagatcagc tgcgtacaga tgatctcgag cgcgcccagg cccatgtaga
    27421 tcaccaccgt ctggcgcggg cgggcgagcg ccggccagtc aaggtcgacg gtgtcgtcct
    27481 tgagatggcc ggtggcaaac accagcgtct gcgcgtgctc gcggtgggtg agcggaatgc
    27541 cggtcgccga ggccgcgcct gctgcggcgg tgatgccggg gacgatctcg cactcgatgc
    27601 cggcgtccag cagcgcctgc atctcctcgc cgccgcgccc gaagatgaag gggtcgccgc
    27661 ccttgagccg caccacgtcc tgcccttcgc gtgcgagctc gaccagcagg cggttgatct
    27721 cgtgctgggg cagcgcgtgg ttgccggcct ccttgcccgc gtagagacgg cgggcgccgg
    27781 gcgggatcag cgcgaccacg gcttcgccga cgagatggtc gtagacgacg gcctgggcgc
    27841 cggtgatcag gcgcagcgcc ttgacggtca gcaggtcggg gtcgccgggg cccgcgccga
    27901 ccagatggac cttgccgtgg ccgtgggcgc gcatgggctg cgggcgttcg ccggggccct
    27961 ccggagcgcc gcggggcggc agggcggcgc gactggcgcg aaggaagcgc gacttgaccg
    28021 cgcctgccgg cgaagcatcc gatcgaaagg ttcctgcctg catgatgtgg gctccagcac
    28081 cgtctcttga aatccgttgc ggcgaaaaag aactccgcca ggggccggaa aaccgcttgt
    28141 ccacgacacc gcgaaatcct cgtgcgggcg catggcgacg tcgttccggc gtccccgaac
    28201 tttatcctcg gagttgatgt ggaaaattaa ttcacatcaa ggatggggct ggcccggaaa
    28261 aaccatactg ccatcacact gttgtttcac atcccgtgtc gtgtaaggag agggcaatgc
    28321 aaaagaaagg tttgttcggt tcggcgctgg cgctggcgat tctgccgctg gccatgagca
    28381 gtgcttgggc ggcggatgcg cccaagctga ccgcagaaga aatggagaag ggcaagctga
    28441 tctacttcga gcgctgcgcg ggttgccacg gtgtgctgcg caagggcgcc accggcaaga
    28501 acctcgagcc gcactggacg aagaccgctc cggatggcac caagctcgag ggcggcaccc
    28561 tcaagctggg taccgagcgt ctcgagaaga tcatctcgta cggcaccgaa ggcggcatgg
    28621 tcaactacga tgacatcctg accaaggaag agatcaacct gatggcgcgc tacatccaga
    28681 atgagccgcc gatcccgccc gagttctcgc tgaaggacat gaaggacagc tggaagctgc
    28741 tggtcccggt caaggaccgt ccgaccaagc agatgaacaa ggtcaacctg aagaacgtgt
    28801 tcgcgatc
//
LOCUS       DAOTIN010000036        27921 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_1948_length_27921_cov_9.014534, whole genome shotgun sequence.
ACCESSION   DAOTIN010000036 DAOTIN010000000
VERSION     DAOTIN010000036.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 27921)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 27921)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27921
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1948_length_27921_cov_9.014534"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..680)
                     /locus_tag="P5537_07545"
     CDS             complement(<1..680)
                     /locus_tag="P5537_07545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HRV77935.1"
                     /translation="MAGRQDTPKQYDESSFRVLKGLEPVRERPGMYTRTDSPAHIIQE
                     VIDNAADEALAGFAKKIHVTLHLDGSVTVADDGRGIPVGLHPEEGVPVVVLAYTRLHA
                     GGKFDKREGNSAYAFSGGLHGVGVSVTNALSTRIEVEVRREGKIHRIDFADGGETISP
                     VRVEGDCGRQTGTRVRVWPDGKYFESPRVPMNELERLLRSKAVLLSGVAVRLDIEQAN
                     GPALSKTWS"
     gene            complement(745..1236)
                     /locus_tag="P5537_07550"
     CDS             complement(745..1236)
                     /locus_tag="P5537_07550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HRV77936.1"
                     /translation="MNRPAVPPSSADRQRLALLIEAEAIQLGEFVELLAREEALLIAG
                     DVDALVALCQDKNDRYRRLQRLSDDRSLLLGRFGQAVTDAVIRDWLAGLPRVLARWDE
                     VIGLARAARERNALNGKLITERMAHNQAALSLLLSAADQPPLYDAEGNTRAIGGGRML
                     GSA"
     gene            complement(1251..1550)
                     /gene="flgM"
                     /locus_tag="P5537_07555"
     CDS             complement(1251..1550)
                     /gene="flgM"
                     /locus_tag="P5537_07555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HRV77937.1"
                     /translation="MKIESSGKAIAPSTAAEARPRSPANPGTTVSAGTEKVQLSSLSS
                     SLAKAEASIAQAPVVDTQRVEEIKQAIAKGEFKIDAGRIADGLIDSVREMLAGQR"
     gene            complement(1663..2388)
                     /gene="flgA"
                     /locus_tag="P5537_07560"
     CDS             complement(1663..2388)
                     /gene="flgA"
                     /locus_tag="P5537_07560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009428 - bacterial-type flagellum basal
                     body, distal rod, P ring [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring formation chaperone
                     FlgA"
                     /protein_id="HRV77938.1"
                     /translation="MTTSLPRRRDTRALRGLSAVLCAALALLPTPANAQQGEGAIEVR
                     VREFLQREVAGLPGEVSIELSPLDPNSQLPACAALEPFLPAGTRAWGRFSVGVRCDSP
                     VTWTAYLQARVAVVADYLVAARPLRAGQVLGPADLGQRRGDLTALSDNVLTDPTQATG
                     HHTRIAVAAGSPLRGDMLRVPHAVRQGQTVNVLGVGAGFRVASEGRAMNNAAPGEKVR
                     VRLADGQVVTGTAQAGGTVELAF"
     gene            2585..2989
                     /gene="flgB"
                     /locus_tag="P5537_07565"
     CDS             2585..2989
                     /gene="flgB"
                     /locus_tag="P5537_07565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009429 - bacterial-type flagellum basal
                     body, proximal rod [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HRV77939.1"
                     /translation="MKTLFDRQIQFHQTALNLQAHRQQLIASNIANADTPHYKARDVD
                     FRAALQGALATAREGVQMATTQAGHIASAPAPSLDSLTGYRTELQSAVDGNTVNMDVE
                     RAAFAENALHYEASVTFINGMLRSMNSAITGQ"
     gene            3001..3405
                     /gene="flgC"
                     /locus_tag="P5537_07570"
     CDS             3001..3405
                     /gene="flgC"
                     /locus_tag="P5537_07570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009425 - bacterial-type flagellum basal
                     body [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HRV77940.1"
                     /translation="MSMLNVFQIAGSALNAQSLRLNATASNLANADSVTSEDGQPYRA
                     KQVVFAARPVAGPAAVGVQVTQVVESAAPLRLVFEPNNPAANPDGYVEMPNVNVVEEM
                     VNMISASRSYQNNAEVMSTARTLLQRTLQIGQ"
     gene            3456..4133
                     /locus_tag="P5537_07575"
     CDS             3456..4133
                     /locus_tag="P5537_07575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook assembly protein FlgD"
                     /protein_id="HRV77941.1"
                     /translation="MSSVTNNQDIAASVLAKINTRTEAKEASASGDMNSRFLTLLTTQ
                     LKNQDPLNPMENAEVTSQLAQMSTVDGIERLNKMFQSFVDGQSAYDSMQAAALVGRGV
                     LVEGKKLTLTESGAVGGFELDAPADSVVLSIKDAAGLEVKQIQLADVKAGSQNFIWDG
                     SAKDGTRAADGAYTVELTALAEGEKVSGRTLEFGPVTSVIRGAAGTDFQVGSLGIFKY
                     DDIKQIL"
     gene            4149..5516
                     /gene="flgE"
                     /locus_tag="P5537_07580"
     CDS             4149..5516
                     /gene="flgE"
                     /locus_tag="P5537_07580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook protein FlgE"
                     /protein_id="HRV77942.1"
                     /translation="MSFQQGLSGLSVSSKALDIISNNVANTNTVGFKAGSAIFADVYA
                     ASLTGSVTGKQVGVGATLGAVRQTFTQGNLTTTNNPLDLAINGDGFFVVGRDNGPDVY
                     TRNGQFELDKEGFIRTPTGEKLKGFQSPVTPGALPTPIGGLKDIQIPIVGSQPMPTSR
                     VEIGGNLDANDLSAAERYPQLFGSTFTLPLPSGENWQDARTYNYSTSIKAYDSLGKSH
                     ELTFYFAKVTPTDTVPPSNVKLNENTWKVYTSVDGNYPLGLNNDGSPNPAQPNMVWTL
                     TFNEKGTVNTPIAGPTAADPLTIPANFTPGANPIRFHVDFTDMRQIGGSYLITELTQD
                     GYTGGELAGVSVGRDGVVTGRYTNGETRELAQLALQTFRNPNALLSIGNNFWEATTES
                     GLTAPSKAGEGVAGVVSAGMIEDANVELTNELVQMIVQQRNYQANAQSIKAQDQVLQT
                     LVNLR"
     gene            5555..6295
                     /gene="flgF"
                     /locus_tag="P5537_07585"
     CDS             5555..6295
                     /gene="flgF"
                     /locus_tag="P5537_07585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgF"
                     /protein_id="HRV77943.1"
                     /translation="MDRLIYTAMTGAKGTMDQQAAVAHNLANVNSTGFRAELHKLRAV
                     EVQTEALHTRAFTVDASVANDLTEGPLQFTGRPFDVALAGKGWLAVQMPDGSEAYTRN
                     GSLAVSANGILQTRDGRPVLGDGGPVSIPPDNEITIGADGTVSASQPDQPGVVNVVAQ
                     LKLVNPPEAGLVRGDDGLFRLQGGAAAPADPNVRVAGGYLEGSNVNVVDQMVQMISLA
                     RQFEMQTRMLSTAEQNDRAAARVLGGQG"
     gene            6535..7317
                     /gene="flgG"
                     /locus_tag="P5537_07590"
     CDS             6535..7317
                     /gene="flgG"
                     /locus_tag="P5537_07590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009426 - bacterial-type flagellum basal
                     body, distal rod [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgG"
                     /protein_id="HRV77944.1"
                     /translation="MIRSLWTARTGLDAQQTSLDVISNNLANVSTNGFKRQRAIFEDL
                     LYQTIRQPGAQSTQQTQISSGLQIGTGVKPVATERIFTQGTLQQTGGSLDVAVQGNGF
                     FQVAMPDGTTAYTRDGAFQLDSQGNVVTASGYTLADNINIPADAVSVTIGKDGTVSVL
                     QAGQAAPVEIGAVQLATFVNPGGLQAAGENLFYETASSGVATPTQPGTNGSGVLNQGY
                     VEVSNVNVAEELVSMIVTQRAYELNSRAISTSDQMLGRLTQL"
     gene            7326..8003
                     /locus_tag="P5537_07595"
     CDS             7326..8003
                     /locus_tag="P5537_07595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009427 - bacterial-type flagellum basal
                     body, distal rod, L ring [Evidence IEA];
                     GO_function: GO:0003774 - cytoskeletal motor activity
                     [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body L-ring protein FlgH"
                     /protein_id="HRV77945.1"
                     /translation="MKLAIASLAAAVFALLSGCAAIQATPPSAVHQPMSVRPEAMETA
                     LPANGAIYQTVQARPLFEDRRARRIGDTITINLVERNTAQKSANANATRNGNMTAGIG
                     PISRLPLSGLNGLELEAESESDFNGKGAAAANNVFNGTITVTVIDVYPNGNLLVSGEK
                     MVAINQGNEFIRFSGVINPNNVTTANTVQSTQVADARIEYRGSGFIDESNTMGWLQRF
                     FVAIMPF"
     gene            8014..9138
                     /locus_tag="P5537_07600"
     CDS             8014..9138
                     /locus_tag="P5537_07600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009428 - bacterial-type flagellum basal
                     body, distal rod, P ring [Evidence IEA];
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring protein FlgI"
                     /protein_id="HRV77946.1"
                     /translation="MSYFASLLLRAAVAFLAVLIFYPASANAAAERIKDLASVGGVRD
                     NQLVGYGLVVGLDGSGDQTTQTPFTVQSIVNMLGNLGVSLPPGTNLQLKNVAAVMVTA
                     NLPAFARPGQAIDVTVSSIGNAKSLRGGTLVMTPLKGADGQVYAIAQGNMVVGGAGAQ
                     GGGASQVINHLSAGRIPGGATVERAVPTALGQGDAVLFELNDADFGTARRVVDAINLV
                     YPGAASALDGRSIQVRAPTDSSARVAFLGHVENLEVTPVQQAAKVIVNSRTGSVVMNQ
                     RVTLQNCAVAHGSLTVTVNNEAQVSQPPPLSGGQTVVTQRGQVDIAQEGGALFNVRGG
                     ANLADVVKALNTLGAKPMDLVSILQAMKAAGALRAELEVI"
     gene            9149..10207
                     /gene="flgJ"
                     /locus_tag="P5537_07605"
     CDS             9149..10207
                     /gene="flgJ"
                     /locus_tag="P5537_07605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly peptidoglycan hydrolase FlgJ"
                     /protein_id="HRV77947.1"
                     /translation="MNKGFQLNALDPNSLGDLKRLARSEGGSDAALRAAAKQFEGLFL
                     QMVMKSMRATTGQNGMMDSEQTRSWQGMLDQQMALEMSQSGGTGLSEMLYRQLGGKAA
                     ARPDATGEAGKTGFDLADVRRRPAIPAVLARAAESVAATAKAALPAEARVPALGAAAT
                     AGEFSALSVYERAALQTRLDAAVRSARDAGGAVSKSAQDFVTEVWPHAQEASRRTGIP
                     AEFMVAQAALETGWGQKQLRHEDGSPSHNLFNIKAGSAWSGRTVAREVTEYADGQAYT
                     ESARFRSYASYAESFRDYARLMTRSPRYAGVLGQTDAAAFARGLQDAGYATDPMYADK
                     LTRIIGGNTLRNALAMAG"
     gene            10275..12254
                     /gene="flgK"
                     /locus_tag="P5537_07610"
     CDS             10275..12254
                     /gene="flgK"
                     /locus_tag="P5537_07610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009424 - bacterial-type flagellum hook
                     [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HRV77948.1"
                     /translation="MSSLLNIGLTGLSASQAYLNTTGHNIANAATPGFHRQNVTQEAR
                     DPQYRGGAFFGTGTGVTGVERSYSQLLEGQVLSADSRRSEYAAYSQFISQLDNVLADA
                     DTGLTPALNEFFGALQNVTSNPTNVAARQALISSGETLSARFRTLDGRISEISEGIET
                     EMRSTLESINGYAAAIAELNERIVTSRAGGAGSAANDLLDQRDQAIAELNRLVKVSTV
                     AQRDGTLTVFIGSGQSLVMGNRAKQLELGEQLDENGRSMIMVRGNSGVVEPLAESLLG
                     GGTLGGLLAARSEGTASAQRSLGLLATTLATEFNNQHAVGLDLDGRLGGEFFKIGGVR
                     VDPPDSGVSVRIDPQQVSALTGSDYSLRYDGTSYQLIDIATGNPVPAAQMQVTTSGGT
                     STIKAHGLIFTAAAGAPTESAFVYPTRYTAGAIEVAIRDPRAVAAAAPVLASLATGEG
                     SSLQVRQSGLADRGSAASGTELGLPALRYTYDAADKRFELDTTAPGVAGWPASLDYDP
                     ATSAAGKSFTLEGPGGLQVELKLSGTPAANDVITLADNKGGVADNRNAALLGALQTDK
                     LMFGSGGQATATLNNAYAQLVAKVGSKTREVQAGERTQTSLLQQAKASRDAVSGVNLD
                     EEAANLVRFQQSYQAAAKVMGVAQRLFDEMLAIAR"
     gene            12269..13177
                     /gene="flgL"
                     /locus_tag="P5537_07615"
     CDS             12269..13177
                     /gene="flgL"
                     /locus_tag="P5537_07615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009424 - bacterial-type flagellum hook
                     [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HRV77949.1"
                     /translation="MRVSTSMIYDQGVIALQKQSAALLHTGQQIATGRKILTPSDDPV
                     GSARALDVSQSKSVNQQFITNQGYAEDALKLVEGQLDGAGEIIQYARDRVLAAGNPAL
                     SPADRQSIATDLRSQFDAMLAIANTRDANGDYLFAGYRSNDPPFEKTDVAGTPGTEYK
                     GDQGSRTMQVSSSRFMPVSFGGEVAFGTAGEGVFKVLGDFITALETGTDVPGAVSTAL
                     GGLDESLDRVLTTRAQIGSQLVEVEQLGFIGSDLDLQYQTTLSDLQDLDYNEAISRLT
                     QQRTFLEAAQQSFLKTTGLSLFNYLS"
     gene            13183..13659
                     /locus_tag="P5537_07620"
     CDS             13183..13659
                     /locus_tag="P5537_07620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV77950.1"
                     /translation="MRRALLVLATCSVLGCASEREGPGPLDRAAGISGPIAGVAGVVW
                     MASELSYLEPEYLAGMLVAYGIYDPLAPTWSIEVSRSGEDRVRMDLHMKRLASGGDGE
                     ARRVFLRNAHELVRAGGFAGFDELSWEEGIESTRPFARRIASGEIRLVRSRTFPEF"
     gene            complement(13671..14468)
                     /gene="fliR"
                     /locus_tag="P5537_07625"
     CDS             complement(13671..14468)
                     /gene="fliR"
                     /locus_tag="P5537_07625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthetic protein FliR"
                     /protein_id="HRV77951.1"
                     /translation="MLSVTAAQLDAWLAALMFPLGRLLGLFASAPVFSNRGVSVRIRL
                     AIGLGVAMAVLPVLPPMPQVPPGGGLGLAIFAQQILIGIAIGFVMRIVFAAVDMAGAL
                     IGMQMGLSFAIFFDPDAGGQTAVLSDFLNLLATLIFLAIDGHLLMIDLLVRSFEWLPV
                     ATDAVDAGGWAFLARSGITVFAAGLLLSLPVIAVLLVANIALGVLTRAAPQLNLFAVG
                     FPITLTAGFIGVLLIMSNFAPVLQSLFERSFDTIGLLLDALAPRPAP"
     gene            complement(14503..14772)
                     /gene="fliQ"
                     /locus_tag="P5537_07630"
     CDS             complement(14503..14772)
                     /gene="fliQ"
                     /locus_tag="P5537_07630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004360999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HRV77952.1"
                     /translation="MTPTAVIELGRQAVEVTLMVSAPLFLAALVTGLIISIFQAATQI
                     NEMTLSFVPKLVAIFVTLVLAGPWMITLLTDFIRRLFESIPAMIG"
     gene            complement(14798..15568)
                     /gene="fliP"
                     /locus_tag="P5537_07635"
     CDS             complement(14798..15568)
                     /gene="fliP"
                     /locus_tag="P5537_07635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004360997.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HRV77953.1"
                     /translation="MKPERRALIHPALLRLALACALAGLPLLATAQALPALTTSPAAG
                     GGTTYSLTIQTLMLMTLLSFIPALVLMTTCFTRIVIVFSLLRQAMGTQTAPPNQVLLG
                     LALFLTFFVMAPVAERVYTEAYLPMSEGRIQFDEALERASVPVKGFMLAQVREPDLAL
                     FAGLAKLPPVEKAEELPMRVVIPAFVTSELKTAFQIGFIVFIPFIIIDMVVASVLMSM
                     GMMMMSPVIVSLPFKIMLFVLVDGWTLLIGSLVQSFAV"
     gene            complement(15558..15920)
                     /gene="fliO"
                     /locus_tag="P5537_07640"
     CDS             complement(15558..15920)
                     /gene="fliO"
                     /locus_tag="P5537_07640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0044781 - bacterial-type flagellum
                     organization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthetic protein FliO"
                     /protein_id="HRV77954.1"
                     /translation="MPELGASLLQMSFGLAVVVGLLFACLWLLRRLSAPRGGGAAVKV
                     LGAAAVGPRERVVLVEIGEDVLVLGVAPGSVTRLHEMKRAELALPADVPGQPPSAGKS
                     FAAWLHQAAERRERRDEA"
     gene            complement(15929..16396)
                     /gene="fliN"
                     /locus_tag="P5537_07645"
     CDS             complement(15929..16396)
                     /gene="fliN"
                     /locus_tag="P5537_07645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004383978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_function: GO:0003774 - cytoskeletal motor activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliN"
                     /protein_id="HRV77955.1"
                     /translation="MADENLITDDDWAAAMQEQAAVEESGDSEADRVAAELAAAAMGD
                     SPYQARPASQLFEDFGAPAAKPGALNDFDMILDIPVQITVELGRTKLSIRNLLQLAHG
                     SVVELDGLAGEPMDVLVNGTLIAQGEVVVVNDKFGIRLTDIITPAERMRKIRN"
     gene            complement(16389..17399)
                     /gene="fliM"
                     /locus_tag="P5537_07650"
     CDS             complement(16389..17399)
                     /gene="fliM"
                     /locus_tag="P5537_07650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004383977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliM"
                     /protein_id="HRV77956.1"
                     /translation="MSADFLSQEEVDALLRGVTGESDEPVADEAGAEGVRPYNLATQE
                     RIVRGRMPTLELINERFARYLRIGLFNYMHRNAEVSAGPIKVQKYAEFVRNLVVPTNL
                     NLITAKPLRGTGLVVFDPNLVFLVVDNMFGGDGRFHTRVEGRDFTPTEQRIIRGMLDV
                     VFTEYVRAWAPVFKLQPEFIRSEMNSQFANIATPSEVVVATSFSVEFGGSQAEMHICF
                     PYSMLEPIRDLLYSAMQSDHLTSDRRWIKLLTRQLQTAEVELACTFGTARVSLRDIVD
                     MRVGDVIPLAVQPLLQAEVDGVPVFECRQGTRNGRYALRVERFITAEETDSPTIPGAQ
                     NG"
     gene            complement(17412..17984)
                     /locus_tag="P5537_07655"
     CDS             complement(17412..17984)
                     /locus_tag="P5537_07655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009425 - bacterial-type flagellum basal
                     body [Evidence IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated FliL family
                     protein"
                     /protein_id="HRV77957.1"
                     /translation="MAKAPAKTEEGDETPKKKGKLGLILIIVLVVIVLVLGALVALLL
                     LKGGKDKEHEEPAAHAAPAAQQLQTTGTVDLTKPPTFIPLEAFTVNLRRDEGDHYLQV
                     VAVMRVADATMDATLKAFMPEIRHRINLLLSSKLPSEVATVEGREALSLAITESINEA
                     LGFKPVRDAAGKPVPNGPVQAVLFTSFIIQ"
     gene            complement(18078..19508)
                     /locus_tag="P5537_07660"
     CDS             complement(18078..19508)
                     /locus_tag="P5537_07660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HRV77958.1"
                     /translation="MSSPFSTSSLGNAAQLRLGSQQARIGISALDGLGAQSDSFSRAL
                     ENRMNTPEPAPRKPESAPPAPLPPERTASAEAPREPERPAGSGPADGESGADTGATSA
                     ARTDAGGASASGSSSSRADGAHAPDNTRGAAAHEDTTQAGASGEAAAAGDAEAVAGQT
                     GHAARLAALAAGVVADTDETPAEAASATASSPTDPAALAGLPAAIAALLAGRAESPSS
                     ADEAAADTGTLQLSADGGRKSLQNSALLPKTDLTATAGGDAGIDADATPAFLLQGREF
                     AAAAAAARSATGAATGGMQADVLEGLGPTGTQAHGLAHTQGATQLLRPSAAAQAASPQ
                     LPVATPAGEPGWAEDVGNQVRWMLGRAESKAELVLTPPNMGKLEVSINLSGDQTTAQF
                     IASSQAARDALERALPQLREALQQAGILLGDANVSTSGQGREGDGREGGGSRGERGEA
                     GAGGNTGAGSASVWLKQQQGMVDTFA"
     gene            complement(19628..20068)
                     /gene="fliJ"
                     /locus_tag="P5537_07665"
     CDS             complement(19628..20068)
                     /gene="fliJ"
                     /locus_tag="P5537_07665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004328705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003774 - cytoskeletal motor activity
                     [Evidence IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export protein FliJ"
                     /protein_id="HRV77959.1"
                     /translation="MPPAFHLQPLLDLASTRTDEAARKLGELVAAERDVEQKLKMLED
                     YRAEYHERFVQAARDGLSPDAWRNYSAFIAKLDDAIAAQRKVVEQSRARTAEGQQAWL
                     AQRTKLKAFDTLAQRHQQTVARSEARQEQKQSDEHAARRGREDA"
     gene            complement(20289..21683)
                     /gene="fliI"
                     /locus_tag="P5537_07670"
     CDS             complement(20289..21683)
                     /gene="fliI"
                     /locus_tag="P5537_07670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018990292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein export ATPase FliI"
                     /protein_id="HRV77960.1"
                     /translation="MNRHQALWRDFLGDGRRLVEGCNPLEVSGRLTRINGLVMEAAGI
                     KLPLGSGCRILVPGGGAVEAEVVGFNGDKLYMMPTDDVFGLAPGARVLPMEVGVPRLV
                     PGKRIGPRRRAADRAKHLPVGDALLGRVVDGAGRPLDGQGPLHTQETRSLQGRAINPL
                     ARAPIAQPLDVGVRAINALLTVGRGQRLGLFAGSGVGKSVLIGMMARYTEAEIIVVGL
                     IGERGREVKEFIEHSLGPEGLARSVVVAAPADTSPLMRMQGAAYATTVAEYFRDQGRQ
                     VLLIMDSLTRYAMAQREIALAIGEPPVTRGYPPSVFARLPALVERAGNGPEGGGSITA
                     FYTVLAEGDDQQDPIADSARAILDGHFVLSRNLADQGHYPAIDIEQSISRAMHNLVGD
                     DHFNVVRQFKQFFSRYQRSRDLIAVGAYQPGGDPLLDMAVKLYPRLEAFLQQGIQEHE
                     TYEGALQKLGQVFA"
     gene            complement(21680..22594)
                     /locus_tag="P5537_07675"
     CDS             complement(21680..22594)
                     /locus_tag="P5537_07675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HRV77961.1"
                     /translation="MSISRHQAVGAYRRWEPEDFDAPAGAAGSAPAADGFASTDPAGA
                     ALNAPSPAVHMPAAPAPSPAPPPAHDAAPPPPAAEAAPALPPDFHLPTAEEIERMHDE
                     MRRAGFEEGRAAGHAEGLEAGRAEGYAEGRAQAEAEAARLAGLADSLDEALRELDGEI
                     AEQLMALAIEMARRMVRLTLAEHPEAILETVRSALLQLPQGHAHIQLHPDDLALVREH
                     LGEQLAHAGHRLQEDARLERGECRIDGQGAQVDATLETRWRRVLESIGHERARWHVTD
                     DEDAAPAPDGTPSAAGIAPPASAAEPPA"
     gene            complement(22709..23710)
                     /gene="fliG"
                     /locus_tag="P5537_07680"
     CDS             complement(22709..23710)
                     /gene="fliG"
                     /locus_tag="P5537_07680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009433 - bacterial-type flagellum basal
                     body, C ring [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HRV77962.1"
                     /translation="MTTPEEGLEKAALLLMTLGPDAAAGVLRQLGPREVQKLTMKMAS
                     MTPQSRETVEPVLIEVNEHFGKGTMIQSDDDQLREMLTKALGDDRANQLLSRMMSGSE
                     TAGIESLKWMDAATAADLIKGEHPQIIATILVHLEYDQAGEILKNFDDRLRNDVVLRI
                     ATLDGVQPTALKELNDALTRMLSGATTVKKAAMGGVRHAAEILNFVGSTAETAVIDNV
                     REYDPELAQKILDEMFVFENLLDVDDRGIQAILREVQSDSLIIALKGAPPELREKVFK
                     NMSSRAAEMLREDLEARGPVRLSEVEAEQKEILKTVRRLAEEGQVMLGGKGGDDGFV"
     gene            complement(23707..25422)
                     /gene="fliF"
                     /locus_tag="P5537_07685"
     CDS             complement(23707..25422)
                     /gene="fliF"
                     /locus_tag="P5537_07685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009431 - bacterial-type flagellum basal
                     body, MS ring [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body MS-ring/collar protein
                     FliF"
                     /protein_id="HRV77963.1"
                     /translation="MAAAENTADLPPGAAPADAQAATRMQQALQNLAALNTRQKIAGA
                     VAVALAIALVAGALLWNRAPEYAVLFSNLDERDGGQIIAELQQRNIPYRMSPTGHAIL
                     VPQAQVHETRLRLAADGLPKGSLAGFELMDGQKLGISQFNEQVNYQRALEGELTRTVQ
                     AIDAVSSARVHLAMPKQTAFLRDDQRPTASVMVNLRGGRILSPDQVAGIVHLVSSSVP
                     RMHAEGVKIVDQNGKLLTEQADPLLRAGLNATQLEYVRLLEQGFIERIDKILAPLVGK
                     GNYGAQVAADVDFNQVEQTAETYKPNPTPDQAIRSQQTTEAFNPQPGAQGVPGALTNQ
                     PPVPATAPITNPQVAGGAGAQGLASGNRSAVLNYELDRNIQHVKQAVGQIKRLSVAVV
                     VNNRTLPGPDGTPTNVPLPDEEIARITNLVREAVGYNADRGDTINVASGAFADDGSEA
                     PVPPWKDPEIIELGKEGLNWLLVLVAILFAYFGVIRPLLRTVVPPKSKEEKKAAGEGE
                     EGEEGEEGEEGVRVTLSGEAGEGEETETFEQRLERARTAARNDPKMVANLIRDWMGLN
                     EEARK"
     gene            25626..26810
                     /locus_tag="P5537_07690"
     CDS             25626..26810
                     /locus_tag="P5537_07690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004375608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HRV77964.1"
                     /translation="MPVGSAVDAAAAAPVLDAAQLAEAFALFSRASEELSTAYAALQA
                     QVGQLSERLSVLMGALPAGVLVVDRAGTVVQANRAAEGLFGGGLAGMAWAALAARLED
                     SGTPGEFVLRRDPATVDGDARRLALSESELDSGAERILLVHDVTDTHRMRLTAERNER
                     LAAMGEMVAGLAHQLRTPLAAALLYTGNLRQPELDPAQRAMVADRALERLRYLERLIR
                     DMLLFARGDSAGRQRFAVCELLAELAHTLEPVARARQVAFAADCGCGEAELVGDRKAL
                     GGALTNLLENGIQACEAGGTLRCEAALVAAADAGIGAPAVRFTVRDSGRGIAPELQER
                     LFEPFFTTRAEGTGLGLAIARGVARAHGGDITLRSTPGQGAEFTLVVPLAAAPNGALE
                     NP"
     gene            26807..>27921
                     /locus_tag="P5537_07695"
     CDS             26807..>27921
                     /locus_tag="P5537_07695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HRV77965.1"
                     /translation="MIETLNILVVEDDAALRDAVCFTLEMAHHRVTGVDGGPAALEAI
                     EREHFNLVVTDLRMQPMDGLQVLHEVRARRPQTPVLLMTAYGDVDKAVAAMRGGACDF
                     LMKPFEPEVLLESVRRYAAVQPAGEDTIAEDPHTRNLLALAARVAESDATVMLSGESG
                     TGKEVFARYLHQHSPRARGPFIAINCAAIPENLLEATLFGYEKGAFTGAQAAQPGKFE
                     QAQGGTILLDEISEMPLGLQAKLLRVLQEREVERVGGKKPVALDIRVLATSNRDMLKE
                     VAAGRFREDLYYRLNVFPIVIPALRERPGDIVPLARHFLARHAARQQRQVRFSPAAEA
                     LLPQYAWPGNVRELENTMHRVLILTQGDEVAAETIRL"
BASE COUNT         4253 a         9832 c         9724 g         4112 t
ORIGIN      
        1 gaccaggtct tgctcagcgc cgggccgttg gcctgctcga tatcgagccg caccgcgacc
       61 cccgacagca gcaccgcctt cgagcgcagc aggcgctcga gctcgttcat cggcacgcgc
      121 ggcgactcga agtacttgcc gtccggccac acccgcaccc gggtgccggt ctggcggccg
      181 cagtcgccct cgacacgcac cgggctgatc gtctcgccgc cgtcggcgaa gtcgatgcgg
      241 tggatcttgc cctcgcgcct gacctcgacc tcgatgcggg tcgacagcgc gttggtcacc
      301 gacacgccga cgccgtgcag gccgcccgag aaggcgtagg ccgagttgcc ctcgcgcttg
      361 tcgaacttgc cgccggcgtg cagacgcgtg taggccagca ccaccaccgg cacgccttcc
      421 tccgggtgca ggccgaccgg gatgccgcgt ccgtcgtcgg ccacggtgac cgagccgtcg
      481 agatggaggg tgacgtggat cttcttcgca aagcccgcga gcgcctcgtc tgcggcgttg
      541 tcgatcacct cctggatgat gtgcgccggg ctgtcggtgc gggtgtacat gcccgggcgc
      601 tcgcgcaccg gctccagccc tttcaggacg cggaaggagg attcgtcgta ctgttttgga
      661 gtgtcttgcc tgccggccat gctgcctgcc cgttcgaact tgcgaagggc gcaaggatag
      721 cagagcgaag ggctgtatgt atgttcaggc gctgccgagc atgcgtccgc cgccgatggc
      781 gcgggtgttg ccctcggcat cgtagagcgg cggctggtcg gcggccgaga gcagcaggct
      841 gagcgcggcc tggttgtgcg ccatgcgctc ggtgatgagc ttgccgttga gggcgttgcg
      901 ctcgcgcgcg gcgcgggcga gcccgatgac ttcgtcccag cgcgccagca cgcgcggcag
      961 accggcgagc cagtcgcgga tcacggcgtc ggtgaccgcc tgcccgaagc ggccgagcag
     1021 caggctgcgg tcgtcggaga gccgctgcag gcggcggtag cggtcgttct tgtcctggca
     1081 gagcgcgacc agcgcatcga cgtcgccggc gatcagcagc gcttcctcgc gcgcgagcag
     1141 ctcgacgaac tcgccgagct ggatcgcttc cgcctcgatc agcagcgcaa ggcgctggcg
     1201 gtcggcggag gaggggggga ccgcaggacg gttcatgcgc ggttaggcgg tcagcgctgg
     1261 ccggcgagca tctcgcgcac gctgtcgatc aggccgtcgg cgatgcggcc ggcgtcgatc
     1321 ttgaattcgc ccttggcgat cgcctgcttg atctcctcga cacgctgggt gtcgacgacc
     1381 ggagcctggg cgatgctcgc ctcggccttg gccaggctgg acgacagcga cgagagctga
     1441 accttctcgg tgccggcgga gacggtggtg ccggggttcg ccgggctgcg cggacgggcc
     1501 tctgccgcgg tggagggggc aatcgccttg cccgagcttt cgattttcat ggcgcagttc
     1561 ccaaacagag tggctctgac gttctcttcg gcacggtcgc gtggaacttg agcgattaaa
     1621 ccatgaaatt tttcacggcc ggcgcttcgt cacgtacggg tctcagaacg ccagttcgac
     1681 cgtgccgccc gcctgtgcgg ttccggtgac gacctggccg tcggccaggc gcacccgcac
     1741 cttctcgccc ggggcggcgt tgttcatcgc gcgcccctcg ctcgccaccc ggaagccggc
     1801 gcccacgccg agcacgttca cggtctggcc ctggcgcacg gcgtggggca cgcgcagcat
     1861 gtcgccgcgc agcgggctgc cggcggcgac cgcgatgcgc gtgtggtgac ccgtcgcctg
     1921 ggtggggtcg gtgaggacgt tgtcggagag cgcggtgagg tcgcccctgc gctggccgag
     1981 gtcggcgggg ccgagcacct ggccggcacg cagcgggcgt gcggcgacca ggtagtcggc
     2041 gaccacggcg acgcgtgcct gcaggtaggc ggtccaggtc accggcgagt cgcaacgcac
     2101 gcccacgctg aaccgccccc aggcgcgcgt gcccgcggga aggaagggct cgagcgccgc
     2161 gcatgctggc agctggctgt tggggtcgag cggcgacagc tcgatcgaaa cctcgccggg
     2221 caggccggcg acctcgcgtt gcaggaactc gcgcacgcgc acctcgatcg cgccttcgcc
     2281 ctgctgggcg ttggcggggg tggggagcag cgcgagggcc gcgcacagca ccgcggacag
     2341 gccgcgcaaa gcacgtgtat cccggcggcg ggggagggaa gtcgtcatgg cccgattgca
     2401 ccacgacccc cgcaggcctg gcaaccggca gcgcccgccg gcaatccttg ccgctggccg
     2461 gcggcgaaat tggccgggct ttgcccccct tatcggcgcc agggtcttgc ccgtccgcgc
     2521 ctaccatcgc tggcatggaa actgcgtccg gaacgtccgg gcgcaccgtc ccgggagcac
     2581 agcgatgaag acccttttcg accggcagat ccagttccac cagaccgcac tgaacctgca
     2641 ggcgcatcgc cagcagctga tcgcctcgaa tatcgccaac gccgacacgc cgcactacaa
     2701 ggcgcgcgac gtggatttcc gcgccgcgct gcagggtgcg ctcgccaccg cgcgcgaggg
     2761 cgtgcagatg gcgaccacgc aggccggcca catcgcgagc gcacccgcgc cctcgctcga
     2821 cagcctcacc ggctaccgca ccgaactgca gtccgcggtg gatggcaaca ccgtgaacat
     2881 ggacgtcgag cgcgccgcct tcgccgagaa cgcgctgcac tacgaggcca gcgtgacctt
     2941 catcaacggc atgctgcgct cgatgaacag cgcgatcacc ggtcagtaag gagaaccgcc
     3001 atgagcatgc tcaacgtctt ccagatcgcc ggctcggcgc tcaacgcgca gtcgctgcgt
     3061 ctcaatgcca ccgcatcgaa cctcgccaac gccgacagcg tcacctccga ggacggccag
     3121 ccctaccgcg ccaagcaggt ggtgttcgcc gcgcggccgg tcgccggccc ggcggcggtc
     3181 ggcgtgcagg tgacccaggt ggtcgagagc gccgcgcccc tgcgcctggt gttcgagccc
     3241 aacaaccccg ccgccaaccc cgacggctac gtcgagatgc ccaacgtcaa cgtggtcgag
     3301 gagatggtga acatgatctc cgcctcgcgt tcctaccaga acaacgccga ggtgatgagt
     3361 acggcacgaa ccttgcttca gcgcaccttg cagatcggcc agtaagcatc ccgcgggcgc
     3421 cgtgaagcaa tgaacgccga aagcaggaga gaggaatgag cagcgtaacg aacaaccagg
     3481 acatcgcggc gagcgtgctc gccaagatca acacgcgcac cgaggccaag gaggcgagcg
     3541 cctccggcga tatgaactcg cgcttcctca ccctgctcac cacccagctg aagaaccagg
     3601 acccgctcaa cccgatggag aacgccgagg tcacctcgca gctcgcgcag atgagcacgg
     3661 tcgatggcat cgagcgcctc aacaagatgt tccagagctt cgtcgatggc cagagcgcct
     3721 acgactcgat gcaggccgcg gcgctggtcg ggcgtggcgt gctggtggaa gggaagaagc
     3781 tgaccctcac cgagtccggc gcggtgggcg gcttcgaact cgacgccccg gccgacagcg
     3841 tggtcctgtc gatcaaggac gccgccggcc tcgaggtcaa gcagatccag ctcgccgacg
     3901 tcaaggcggg cagccagaac ttcatctggg acggcagcgc caaggacggc acgcgcgccg
     3961 ccgacggcgc ctacacggtc gagctgaccg cgctcgccga gggcgagaag gtcagcggcc
     4021 gcacgctcga gttcggcccg gtcaccagcg tgatccgcgg cgccgcgggc accgacttcc
     4081 aggtcggctc gctcggcatc ttcaagtacg acgacatcaa gcagattctc tgatccggag
     4141 ccccgatcat gtctttccag caaggtttga gcggtctgag cgtttcctcc aaggccctgg
     4201 acatcatctc caacaacgtc gccaacacca acacggtggg tttcaaggcc ggctcggcga
     4261 tcttcgccga cgtctacgcg gcctcgctga ccggttcggt cacgggcaag caggtcggcg
     4321 tcggcgccac gctcggtgcg gtgcggcaga ccttcaccca aggcaacctc accaccacca
     4381 acaacccgct cgacctggcg atcaacggcg acggcttctt cgtggtcggg cgtgacaacg
     4441 ggccggacgt gtacacccgc aacggccagt tcgagctcga caaggaaggc ttcatccgca
     4501 cgcccaccgg cgaaaagctc aagggcttcc agagcccggt cacgccgggt gcgctgccca
     4561 cgccgatcgg tggcctcaag gacatccaga tcccgatcgt cggctcgcaa ccgatgccga
     4621 ccagccgggt ggaaatcggc ggcaacctcg atgcgaacga cctgagcgcg gcggagcgct
     4681 acccgcaact cttcggttcc accttcacct tacccttgcc ctcgggcgag aactggcagg
     4741 atgcgcggac ctacaactac tcgacctcga tcaaggccta cgacagcctg gggaaatcgc
     4801 acgagctcac cttctacttc gcgaaggtga cgccgaccga tacggtccct ccctccaacg
     4861 tcaaactcaa cgagaacacc tggaaggtct atacgagcgt ggatgggaac tatccgctcg
     4921 ggctcaacaa cgatggcagt cccaatccgg cgcagcccaa catggtgtgg accctgacct
     4981 tcaacgaaaa gggcacggtc aacacgccga tcgccgggcc gacagcggcc gatccgctga
     5041 cgattcctgc gaatttcact cctggcgcga acccgatccg cttccacgtc gacttcaccg
     5101 acatgcgtca gatcggcggt tcctatctga tcaccgagct cacccaggac ggctacaccg
     5161 gcggcgagct cgccggcgtc agcgtggggc gcgacggcgt cgtcaccggc cgctacacca
     5221 acggcgagac gcgcgagctt gcccaactcg cgctgcagac cttccgcaac cccaacgcgc
     5281 tgctgtcgat cggcaacaac ttctgggaag cgaccaccga atccggcctg accgcgccgt
     5341 ccaaggccgg cgagggagtc gcgggcgtcg tctcggcggg catgatcgag gacgccaacg
     5401 tcgagctcac caacgaactc gtgcagatga tcgtccagca gcgcaactac caggccaacg
     5461 cgcaatccat caaggcgcag gaccaggtcc tgcagaccct ggtgaacctg cgctgatcct
     5521 gaaaccacag cccgactaag ccaagaggcc agcgatggac cgcctgatct acaccgcgat
     5581 gaccggcgcc aagggcacca tggaccagca ggcggcggtc gcgcacaacc tcgccaacgt
     5641 caattccacg ggcttccgcg ccgagctgca caagctgcgt gcagtcgagg tgcagaccga
     5701 ggccttgcac acccgagcct tcaccgtcga tgccagcgtc gccaacgacc ttaccgaggg
     5761 gccgctgcag tttaccggcc ggcccttcga cgtcgcgctc gccggcaagg gctggctggc
     5821 ggtgcagatg cccgacggtt cggaagccta tacccgcaac ggcagcctcg cggtgagcgc
     5881 caacggcatc ctgcagacgc gcgatggcag gccggtgctc ggcgacggcg ggccggtgag
     5941 cattccaccc gacaacgaga tcaccatcgg cgccgacggc acggtgtcgg cctcgcagcc
     6001 cgaccagccg ggggtggtca acgtggtcgc ccagctcaag ctggtgaatc cgcccgaggc
     6061 cgggctggtg cgcggcgacg acggcctctt ccgcctgcag ggcggggcgg ccgcgccggc
     6121 cgaccccaac gtgcgcgtgg cgggcggcta tctcgagggc agcaacgtca acgtggtcga
     6181 ccagatggtg cagatgatct cgctcgcccg ccagttcgag atgcagaccc gcatgctgtc
     6241 gacggccgag cagaacgacc gcgcggctgc ccgggtcctc ggcggccagg gctgatcggg
     6301 ctcgcgcccc acagcaggcc gggccgcatc gagcgcccgg cttttttctt gttcgcgtcc
     6361 ggcctcctcg attagcacgg tttttgcgtt gcttatcgca ggatggtcgg tgacaacgcc
     6421 ggcctagact gatcccatcg aaaaagcggc aacgcggcgg caattacggg tcgatctccg
     6481 gaccccgcac ggcaaaacct gccgcaccgg caacgcaagg caaaggaacc catcatgatc
     6541 cgctccctgt ggaccgcccg taccgggctg gatgcccagc aaacctcgct ggacgtgatc
     6601 tccaacaacc tggccaacgt ctccaccaac ggcttcaagc gccagcgcgc gatcttcgag
     6661 gacctgctct accagaccat ccgccagccc ggcgcgcagt cgacccagca gacgcagatc
     6721 tccagcggcc tgcagatcgg caccggcgtc aagccggtgg cgaccgagcg catcttcacc
     6781 cagggcacgc tgcagcagac cggcggctcg ctcgacgtgg cggtgcaggg caacggcttt
     6841 ttccaggtcg cgatgcccga cggcaccacc gcctacaccc gcgacggcgc cttccagctc
     6901 gacagccagg gcaacgtcgt caccgccagc ggctacacgc tcgccgacaa catcaacatc
     6961 cccgccgacg cggtttccgt gacgatcggc aaggacggca cggtgagcgt gctgcaggcc
     7021 ggccaggccg cgccggtgga gatcggcgcc gtccagctcg ccaccttcgt taacccgggc
     7081 ggcctgcagg ccgcgggcga gaacctgttc tacgagaccg cctcgagcgg cgtggccacg
     7141 cccacccagc cgggcacgaa cggctcgggc gtgctcaacc agggctatgt cgaggtctcc
     7201 aacgtcaacg tcgccgagga actggtgagc atgatcgtga cccagcgcgc ctacgagctc
     7261 aactcgcgcg cgatctcgac ctccgaccag atgctcggcc ggctgaccca gctgtgaggc
     7321 gcccgatgaa gctcgcaatc gcctcgctcg ccgccgccgt attcgccttg ctctcgggct
     7381 gtgcggccat ccaggccacg ccgccctccg cggtgcacca gcccatgagc gtgcgtcccg
     7441 aggccatgga gaccgcgctg ccggccaatg gcgcgatcta ccagaccgtg caggcgcgtc
     7501 ccctgttcga ggaccggcgt gcgcggcgga tcggcgacac gatcacgatc aacctggtcg
     7561 agcgcaacac cgcgcagaag agcgccaacg ccaacgccac ccgcaacggc aacatgacgg
     7621 ccggcatcgg cccgatcagc cgcctgccct tgagcgggct gaacggcctc gagctcgagg
     7681 ccgagtccga gtccgacttc aacggcaagg gcgccgcggc ggccaacaac gtcttcaacg
     7741 gcacgatcac cgtcaccgtg atcgacgtgt acccgaacgg caacctgctg gtttcgggcg
     7801 agaagatggt ggcgatcaac cagggcaacg agttcatccg cttctcgggc gtgatcaatc
     7861 cgaacaacgt gaccaccgcc aacaccgtgc aatcgaccca ggtggcggat gcgcgcatcg
     7921 agtaccgcgg cagcggcttc atcgacgagt ccaacaccat gggctggctg cagcgcttct
     7981 tcgtcgccat catgccgttc tgagggccgc gtcatgtcct atttcgcctc cttgctcctg
     8041 cgtgccgcgg tcgccttcct ggccgtgctg atcttctacc cggcctcggc caacgccgcc
     8101 gccgagcgca tcaaggacct cgcctcggtg ggcggcgtgc gcgacaacca gctcgtcggc
     8161 tacggcctgg tggtgggcct ggacggctcg ggcgaccaga ccacgcagac gcccttcacc
     8221 gtgcagagca tcgtcaatat gctcggcaac ctcggcgtga gcctgccgcc cggcaccaac
     8281 ctgcagttga agaacgtcgc cgcggtgatg gtcaccgcca acctgccggc cttcgcccgc
     8341 ccggggcagg cgatcgacgt caccgtatcc tcgatcggca acgccaagag cctgcgcggc
     8401 ggcaccctgg tgatgacgcc gctcaagggc gccgacggcc aggtctatgc gatcgcccag
     8461 ggcaacatgg tggtgggcgg cgcgggcgcg cagggcggcg gcgcctcgca ggtcatcaac
     8521 cacctgtcgg ccggtcgcat tcccggcggc gccaccgtcg agcgtgcggt gccgaccgcg
     8581 ctcgggcagg gcgacgcggt gctgttcgag ctcaacgacg ccgacttcgg caccgcacgc
     8641 cgggtggtcg acgccatcaa cctggtctac cccggcgcag cgagcgcgct cgacgggcgc
     8701 agcatccagg tgcgcgcgcc caccgactcc agcgcgcgcg tcgccttcct cggccacgtc
     8761 gagaacctcg aggtcacacc cgtgcagcag gccgccaagg tcatcgtcaa ctcgcgcacc
     8821 ggctcggtgg tcatgaacca gcgcgtgacg ctgcagaact gcgccgtcgc ccacggcagc
     8881 ctgacggtca cggtcaacaa cgaggcccag gtcagccagc cgccgccgct ctcgggcggt
     8941 cagacggtgg tcacccagcg cggccaggtc gacatcgccc aggagggcgg cgcgctcttc
     9001 aacgtgcgcg gcggcgccaa cctcgccgac gtggtcaagg cgctcaacac cctgggtgcc
     9061 aagccgatgg acctcgtcag catcctgcag gccatgaagg cggccggcgc gctgcgcgcc
     9121 gagctcgagg tcatctgagg gggcggtcat gaacaagggc ttccagctca acgcgctcga
     9181 ccccaattcg ctcggcgacc tcaagcgcct ggcgcgcagc gagggtggct cggacgccgc
     9241 cctgcgcgcc gcggccaagc agttcgaagg tctcttcctg cagatggtca tgaagtcgat
     9301 gcgcgcgacc accggccaga acggcatgat ggacagcgag cagacgcgct cctggcaggg
     9361 catgctcgac cagcagatgg cgctcgagat gtcgcagtcg ggcggcacgg ggctttccga
     9421 gatgctctac cgccagctcg gcggcaaggc cgcagcgcgg cccgatgcga cgggcgaggc
     9481 cggcaagacc ggcttcgacc ttgccgacgt gcgccgccgc ccggcaattc ctgccgtcct
     9541 cgcacgtgcc gcggaaagcg ttgccgccac ggcaaaggcc gccttgccgg ccgaggcgcg
     9601 cgtgccggcg ctgggtgcgg ccgcgaccgc aggcgagttc tccgcgctgt cggtgtacga
     9661 gcgcgccgcg ctgcagaccc ggctcgacgc tgcggtgcgc agcgcgcgtg acgccggcgg
     9721 cgcggtgtcg aaatccgcgc aggacttcgt caccgaggtg tggccgcatg cgcaggaagc
     9781 cagccgccgc accggcatcc cggccgagtt catggtcgcc caggcggcgc tcgagaccgg
     9841 ctgggggcag aagcagctgc gccacgagga cggcagcccg agccacaacc tcttcaacat
     9901 caaggccggc agcgcatggt cgggccgcac cgtcgcgcgc gaggtcaccg agtacgccga
     9961 tggccaggcg tacaccgagt ccgcacgctt ccgttcctac gcttcgtacg ccgaatcctt
    10021 ccgcgactac gcccggttga tgacgcgcag cccgcgctac gccggcgtgc tcggccagac
    10081 cgacgcggcg gccttcgcgc gcggcctgca ggacgccggc tacgccaccg acccgatgta
    10141 cgccgacaag ctcacccgca tcatcggtgg caacaccttg cgcaacgcgc tggcaatggc
    10201 tgggtgagcg aggtcctggg cgctggcaag gatcttgcat atagagcctc gaaccagcgc
    10261 atcagggaaa catcatgtcg tccttgctca atatcggact gaccgggctc agcgcctccc
    10321 aggcctacct caacaccacc ggccacaaca tcgccaacgc ggcgacgccg ggcttccatc
    10381 gccagaacgt cacccaggaa gcgcgcgacc cgcagtaccg gggcggcgcc ttcttcggca
    10441 ccggcacggg tgtcaccggc gtggagcgca gctacagcca gctgctcgag ggccaggtgc
    10501 tgagcgccga cagccggcgt tcggagtacg ccgcctacag ccagttcatc agccagctcg
    10561 acaacgtgct cgccgacgcc gacaccggcc tcacccccgc gctcaacgag ttcttcggtg
    10621 cgctgcagaa cgtcacctcc aatccgacca acgtcgccgc ccgccaggcg ctgatctcca
    10681 gcggagagac cctgtccgcg cgcttccgca cgctggacgg acgcatctcc gagatctcgg
    10741 agggcatcga gaccgagatg cgcagcaccc tcgagagcat caacggctac gccgccgcga
    10801 tcgccgagct caacgagcgc atcgtgacct cgcgtgccgg cggtgccggc tcggccgcca
    10861 acgacttgct cgaccagcgc gaccaggcga tcgccgagct caaccgcctg gtcaaggtga
    10921 gcacggtggc gcagcgcgac ggaaccctga cggtcttcat cggctccggg cagagcctgg
    10981 tcatgggcaa ccgtgccaag caactcgagc tgggtgagca gctcgacgag aacgggcgct
    11041 cgatgatcat ggtgcgcggc aactccgggg tggtggagcc gctggccgag agcctgctcg
    11101 gcggcggcac gctcggtggc ctgctggccg cgcgcagcga gggcacggcc tcggcgcagc
    11161 gcagcctcgg cctgctggcg accacgctgg cgaccgaatt caacaaccag cacgccgtcg
    11221 gcctcgacct ggacggccgg ctgggcggcg agttcttcaa gatcggtggc gtgcgggtcg
    11281 atccgcccga cagcggcgtg agcgtgcgga tcgacccgca acaggtctcg gcgctcaccg
    11341 gcagcgacta ctccttgcgc tacgacggga cgtcctacca gctcatcgat atcgccaccg
    11401 ggaacccggt gcctgccgcg cagatgcagg tcacgacctc ggggggcacg agtacgatca
    11461 aggcgcacgg gctgatcttc accgctgcgg cgggtgcgcc gaccgagtcc gccttcgtct
    11521 atccgacccg ttacaccgcg ggggcgatcg aggtggcgat ccgcgacccg cgtgcggtcg
    11581 ctgctgcggc gccggtgctg gccagcctgg ccaccggaga aggcagctcg ctgcaggtcc
    11641 ggcaatccgg ccttgccgat cgcggcagtg ctgcgtccgg aaccgagctc ggcctgccgg
    11701 cactgcgcta cacctacgac gcggcggaca agcgcttcga gctcgacacg acggcgcccg
    11761 gagtggccgg ctggcctgcg agcctggact acgatccggc gaccagtgcc gcgggcaagt
    11821 ccttcacgct ggaagggccg ggaggcctcc aagtcgagct caagctttcc ggaactcctg
    11881 ccgctaacga tgtcatcacg ctcgccgaca acaagggcgg tgtcgccgac aaccgcaacg
    11941 ccgcgctgct cggtgctctg cagaccgaca agctgatgtt cggcagcggc gggcaggcca
    12001 ccgccacgct caacaacgcc tacgcgcagc tggtcgccaa ggtcggcagc aagacgcgcg
    12061 aggtgcaggc gggcgagcgg acccagacct cgctgctgca gcaggccaag gcttcgcgcg
    12121 acgcggtctc gggggtgaac ctggacgagg aggcggccaa cctggtgcgc ttccagcaga
    12181 gctaccaggc cgcggccaag gtgatgggcg tggcccagcg cctgttcgat gaaatgctgg
    12241 cgatcgcccg ctgaggaggg agcacaccat gcgcgtatcg accagcatga tctacgacca
    12301 gggcgtcatc gccctgcaga agcagtccgc cgcgctgctg cataccggcc agcagatcgc
    12361 caccggccgc aagatcctca ccccctcgga cgatccggtg ggctccgcgc gcgcgctcga
    12421 cgtcagccag tcgaagagcg tcaaccagca gttcatcacc aaccagggct atgccgagga
    12481 cgcgctcaag ctggtcgaag gccagctcga cggcgccggc gagatcatcc agtacgcgcg
    12541 cgaccgggtg ctcgccgccg gcaatccggc gctctcgccc gccgaccgcc agtccatcgc
    12601 caccgacctg cgcagccagt tcgacgccat gctggcgatc gccaacacgc gcgacgccaa
    12661 cggcgattac ctcttcgcgg gctaccgttc caacgatccg ccgttcgaga agacggacgt
    12721 cgccggtacg cccggcaccg aatacaaggg cgaccagggc tcgcgcacca tgcaggtctc
    12781 ttcgtcgcgc ttcatgccgg tcagcttcgg aggcgaggtg gcgttcggga ccgcgggcga
    12841 aggggtgttc aaggtgctgg gtgatttcat cactgcgctc gagaccggga ccgacgtgcc
    12901 gggtgccgtg agcacggccc ttggcggcct cgacgagagc ctcgatcgcg tgctcaccac
    12961 gcgcgcccag atcggctcgc agctggtcga ggtcgagcag ctcggcttca tcggcagcga
    13021 cctcgacctg cagtaccaga ccacgctgtc cgacctgcag gacctcgact acaacgaggc
    13081 gatctcgcgc ctgacccagc agcgcacctt cctcgaagcc gcccagcagt ccttcctcaa
    13141 gacgaccggg ctgtcgctgt tcaactacct cagctgaccg ccatgcgccg cgcgcttctc
    13201 gtccttgcaa cgtgttccgt gctcggctgt gccagcgagc gcgagggccc cggcccgctg
    13261 gatcgcgccg ccgggatatc ggggccgatc gccggtgtgg cgggcgtggt gtggatggcg
    13321 agcgagctgt cctacctcga gccggaatac ctcgccggca tgttggtggc ctacggtatc
    13381 tacgacccgc tcgcgcccac ctggtcgatc gaggtcagcc gcagcggcga ggaccgcgtg
    13441 cgcatggacc tgcacatgaa gcggctcgcc agcggcggcg acggcgaggc gcgccgggtg
    13501 ttcctgcgca acgcgcacga gctcgtgcgg gcgggcggct tcgccggctt cgacgagctg
    13561 agctgggagg agggcatcga gtccacccgc cccttcgccc gccgcatcgc cagcggcgag
    13621 atccgcctgg tgcgctcgcg caccttcccg gagttctgag cgcgccccgg tcagggtgcc
    13681 gggcgcggcg cgagcgcgtc gagcagcagg ccgatggtgt cgaagctgcg ctcgaacagg
    13741 ctctgcagca ccggcgcgaa gttgctcatg atcagcagca cgccgatgaa gcccgcggtc
    13801 agcgtgatcg gaaagcccac cgcgaacagg ttgagctgcg gcgccgcgcg tgtcagcacg
    13861 ccgagcgcga tgttggccac gagcagcacc gcgatcaccg gcagcgacag cagcagcccg
    13921 gccgcgaaca cggtgatgcc gctgcgcgca aggaaggccc agccaccggc gtccaccgcg
    13981 tcggtcgcca ccggcagcca ctcgaagctg cgcaccagca ggtcgatcat cagcaggtgg
    14041 ccgtcgatgg cgaggaagat cagggtcgcg agcaggttga ggaagtcgga cagcaccgcg
    14101 gtctgaccgc cggcgtcggg gtcgaagaag atcgcgaacg acaggcccat ctgcatgccg
    14161 atcagcgcgc cggccatgtc caccgcggcg aacacgatgc gcatgacgaa gccgatggcg
    14221 atgccgatca ggatctgctg cgcgaagatc gccaggccca ggccgccgcc gggcggcacc
    14281 tgcggcatcg gcggcagcac cggcagcacc gccatcgcca cgcccagccc gatcgccagg
    14341 cggatacgca ccgacacgcc gcggttggag aacaccggcg ccgaggcgaa cagcccgagc
    14401 aggcgcccga gcgggaacat cagcgcggcc agccaggcgt cgagctgggc ggcggtgacg
    14461 gagagcatgc gggcagcggc gggcgagggg cggggaagcg actcagccga tcatcgccgg
    14521 gatggactcg aacagccggc ggatgaagtc ggtgagcagg gtgatcatcc acggtccggc
    14581 cagcaccagg gtcacgaaga tcgccaccag cttgggtacg aaggagagcg tcatctcgtt
    14641 gatctgggtg gcggcctgga agatgctgat gatcaggccg gtgaccagtg cggcgaggaa
    14701 gagcggcgcc gacaccatca gggtgacctc gacggcctgg cggccgagct cgatgacggc
    14761 ggtgggggtc atggtcgttc tcctcgggcg ggcgcggtca caccgcgaag ctctgcacca
    14821 gcgagccgat cagcagcgtc cagccgtcga ccagcacgaa cagcatgatc ttgaagggca
    14881 gcgacacgat caccggcgac atcatcatca tgcccatgga catcagcacc gaggccacga
    14941 ccatgtcgat gatgatgaag gggatgaaga cgatgaagcc gatctggaag gcggtcttga
    15001 gctcggaggt cacgaaggcg gggatcacca cccgcatcgg cagttcctcg gccttctcca
    15061 ccggtggcag cttggccagc ccggcgaaga gcgcgaggtc gggctcgcgc acctgcgcga
    15121 gcatgaagcc cttgaccggc accgaggcgc gctcgagcgc ctcgtcgaac tggatgcggc
    15181 cctcggacat cggcaggtag gcctcggtgt agacgcgctc ggcgaccggg gccatcacga
    15241 agaaggtcag gaagagcgcg aggccgagca gcacctgatt gggcggtgcc gtctgcgtgc
    15301 ccatggcctg gcgcagcagc gagaacacga tgacgatgcg ggtgaagcag gtcgtcatca
    15361 gcaccaatgc cgggatgaag ctcaggagcg tcatcagcat cagcgtctgg atggtgaggc
    15421 tgtaggtcgt gccgccgccg gccgccgggc tggtggtgag cgcgggcagg gcctgggccg
    15481 tcgccagcag gggcaggccg gcgagcgcgc aggcgagcgc gaggcgcagc agggccgggt
    15541 ggatcagggc gcggcgctca ggcttcatcg cgccgctccc tgcgctccgc ggcctggtgc
    15601 agccaggcgg cgaagctctt gccggcggac gggggctggc ccggcacgtc ggccggcagc
    15661 gccagctcgg cgcgcttcat ctcgtgcagg cgggtcacgc tgcccggcgc cacgcccagc
    15721 accagcacgt cctcgccgat ctcgaccagc accacgcgct cgcgcggacc gaccgcggcc
    15781 gcgccgagca ccttgaccgc cgcgccgccg ccgcgcggcg cggacaggcg gcggagcagc
    15841 cacaggcagg cgaacagcag gccgacgacc accgccaggc cgaagctcat ctgcaggagg
    15901 ctggcgccga gttcgggcat cgcggggctc agttgcggat cttccgcatg cgctcggcgg
    15961 gggtgatgat gtcggtgagg cggatgccga acttgtcgtt caccaccacg acctcgccct
    16021 gggcgatgag ggtgccgttg accagcacat ccatgggctc gccggccagg ccgtcaagct
    16081 cgaccaccga gccgtgggcg agctgcagca ggttgcggat cgacagcttg gtgcgcccga
    16141 gctccacggt gatctgcacc gggatgtcga ggatcatgtc gaagtcgttg agcgcgccgg
    16201 gcttggctgc gggggcgccg aagtcctcga agagctggct ggcggggcgg gcctggtagg
    16261 gcgagtcgcc catcgccgcg gccgcaagct cggcggcgac gcgatcggcc tcgctgtcgc
    16321 cgctctcctc gacggcggcc tgctcctgca tcgcggctgc ccagtcgtcg tcggtaatca
    16381 ggttctcgtc agccattctg ggctcccgga atcgtggggg aatcggtttc ctcggcggtg
    16441 atgaagcgct ccacgcgcag cgcgtagcgc ccgttgcgcg tgccctggcg gcattcgaac
    16501 accggcacgc cgtcgacctc ggcctgcagc agcggctgca cggcgagcgg gatcacgtcg
    16561 ccgacgcgca tgtcgacgat gtcgcgcagg ctcaccctgg cggtgccgaa ggtgcacgcg
    16621 agctcgacct cggcggtctg cagctgccgc gtcagcagct tgatccagcg ccggtccgag
    16681 gtcaggtggt cgctctgcat ggcggagtag agcaggtcgc ggatgggctc cagcatcgag
    16741 tacgggaagc agatgtgcat ctcggcctgg gagccgccga actcgaccga gaagctggtc
    16801 gccaccacca cctcggaggg ggtggcgatg ttggcgaact gcgaattcat ctccgagcgg
    16861 atgaattcgg gctgcagctt gaacaccggc gcccaggcac gcacgtattc ggtgaagacg
    16921 acgtcgagca tgccgcggat gatgcgctgc tcggtcgggg tgaagtcgcg cccttccacg
    16981 cgggtgtgga agcggccgtc gccgccgaac atgttgtcca ccaccaggaa gaccaggttg
    17041 gggtcgaaca cgaccagccc ggtgccgcgc agcggcttgg cggtgatcag gttgaggttg
    17101 gtgggcacca ccaggttgcg cacgaactcg gcgtacttct gcaccttgat cggccccgcc
    17161 gagacctcgg cgttgcggtg catgtagttg aacaggccga tgcgcaggta gcgcgcgaag
    17221 cgctcgttga tgagctcgag cgtgggcatg cgcccgcgca cgatgcgctc ctgcgtggcg
    17281 aggttgtacg ggcgtacccc ctccgccccg gcctcgtccg cgaccggctc gtccgactcg
    17341 ccggtgacgc cccgcagcag ggcgtcgacc tcttcctggg agagaaagtc cgcggacatg
    17401 gcggcgttcc cttactggat gatgaaggag gtgaacagca cggcctgcac cgggccgttg
    17461 ggcaccggct tgccggccgc gtcgcgcacc ggcttgaatc cgagggcctc gttgatgctc
    17521 tcggtgatcg ccagcgacaa ggcctcgcgg ccctcgacgg tggcgacctc ggagggcagc
    17581 ttgctcgaca gcagcaggtt gatgcggtgg cggatctccg gcatgaaggc cttcagggtc
    17641 gcgtccatgg tggcgtcggc cacgcgcatc accgccacca cctgcaggta gtggtcgccc
    17701 tcgtcgcgcc gcaggttgac cgtgaaggcc tcgagcggga tgaaggtagg cggcttggtg
    17761 aggtccaccg tgccggtggt ctgcagctgc tgcgcagccg gtgcggcgtg ggccgcgggc
    17821 tcctcgtgct ccttgtcctt gccgcccttg agcagcagca gtgcgacgag cgcacccagc
    17881 acgagcacga tcaccacgag cacgatgatg aggatcaggc cgagcttgcc cttcttcttg
    17941 ggggtctcgt cgccttcctc ggtctttgcc ggcgccttgg ccatgcgaat ctcctgtagt
    18001 acggattgaa ttatccggga ggtccgcact cgccaaagcg ccgattagtg gggcaagccc
    18061 gccccaattc gcgcgcttca ggcgaaggtg tcgaccatcc cctgttgctg cttcagccac
    18121 acgctcgcgc tgcctgcgcc ggtgttgcca cctgcgcccg cctcgccgcg ttcgccacga
    18181 ctgcccccgc cttcgcggcc atccccctcg cggccctggc cggaggtgct cacgttggcg
    18241 tcgcccagca ggatccccgc ctgctgcagc gcctcgcgca gctgcgggag cgcacgctcg
    18301 agcgcgtcgc gtgccgcctg gctggaggcg atgaactgcg ccgtcgtctg gtcgccggag
    18361 aggttgatcg acacctcgag cttgcccatg ttcggcggcg tcagcacgag ctcggccttg
    18421 ctctcggcgc ggccgagcat ccagcgcacc tggttgccga cgtcctccgc ccagcccggc
    18481 tcgcccgccg gagtcgccac cggcagttgc ggcgacgcgg cctgcgcggc agcggacggg
    18541 cgcagcagct gcgtggcacc ctgggtgtgc gccaacccgt gcgcctgggt gccggtcggg
    18601 cccagcccct cgagcacgtc cgcctgcatg ccgcccgtgg cggctccggt cgcgctgcgc
    18661 gccgccgcgg ctgcggcggc gaactcgcgg ccctgcagca ggaaggccgg agtggcgtcg
    18721 gcatcgatac ccgcgtcgcc gccggccgtg gccgtcagat cggttttcgg cagcagggcg
    18781 gaattctgaa gcgacttgcg tccgccgtct gcgctcagtt gcagcgtgcc ggtatcggca
    18841 gcggcctcgt ccgcgctgga aggagattcc gcacgaccgg cgaggagtgc ggcaatcgct
    18901 gccggcagtc cggcaagcgc tgccgggtcg gtgggcgagc ttgccgtggc ggaggccgct
    18961 tcggcaggtg tttcgtcggt gtcggcgacg acgcccgcag ccagcgcagc gagacgcgcg
    19021 gcgtggccgg tctggcccgc aacggcctcg gcatcgccgg cagcggcggc ctcgccggat
    19081 gcgccagcct gcgtggtgtc ttcatgcgcg gcagcgcccc gtgtgttgtc gggggcgtgc
    19141 gcgccgtccg cgcgcgacga ggaggatccg gaagccgagg ctcctccggc gtccgtccgg
    19201 gcggcgctcg tggcgccggt atccgcgccc gattcgccat ccgcggggcc gcttccggcc
    19261 gggcgctcgg gctcgcgagg ggcttcggcc gaggccgtgc gctcgggcgg aagcggggcc
    19321 ggcggcgcgg attcgggctt gcgcggcgcc ggctccggcg tgttcatgcg gttctcgagc
    19381 gcgcgcgaga agctgtccga ctgcgcgccg aggccatcca gggcggagat gccgatgcgt
    19441 gcctgctggg agccgaggcg aagctgcgcg gcgttgccga ggctggaagt ggagaacggg
    19501 gaggacatgg ttgcgggcct ctcatgggct gggtgcgatg gatcgaggac gatccgacag
    19561 tccatcaaaa gcaagcctca tgccatgggt acgtcagcgg atcgggcgcc tgccgcggct
    19621 gcccgcgtca ggcgtcttcg cggccgcgcc gcgcagcgtg ctcgtccgac tgcttctgct
    19681 cctggcgcgc ctcgctgcgc gcgacggtct gctggtggcg ctgggcgagg gtgtcgaagg
    19741 ccttcagctt ggtgcgctgg gccagccagg cctgctggcc ttcggcggtg cgcgcgcggg
    19801 attgctcgac caccttgcgc tgggcggcga tcgcgtcgtc gagcttggcg atgaaggcgc
    19861 tgtagttgcg ccacgcgtcg gggctcaggc catcgcgtgc ggcctgcacg aagcgctcgt
    19921 ggtattccgc gcggtagtcc tcgagcatct tcagcttctg ttccacgtcg cgctcggctg
    19981 cgaccagctc gccgagcttg cgtgcggctt cgtcggtgcg ggtgctggcg agatcgagca
    20041 ggggctgaag gtggaaggcg ggaggcatcg gcgtcgtttc ggggcgtttt tgcaaacggc
    20101 attctagccg ctcgcgacct gcccgaggtg ggcatatcgc ggccggccgg ccgtcgaccg
    20161 tgacgaaatg ctcgcgtcga tgtcgctgcg ggcggcgcgg cgcaggtcgc gaatgccgca
    20221 cgctccccgc gcctaacgcc taacgcctaa cgcctaacgc ctaacgcctg acgcctcacg
    20281 cgaacgcctc acgcgaacac ctgcccgagc ttctgcaggg cgccctcgta ggtctcgtgc
    20341 tcctggatgc cctgctgcag gaaggcctcc agcctgggat agagcttgac cgccatgtcg
    20401 agcaggggat cgccgccggg ctggtaggcg ccgaccgcga tgaggtcgcg cgagcgctgg
    20461 tagcgcgaga agaattgctt gaactggcgc accacgttga agtggtcgtc gcccaccagg
    20521 ttgtgcatcg cgcgcgagat cgactgctcg atgtcgatcg ccgggtagtg gccctggtcg
    20581 gcgaggttgc gcgagagcac gaagtggccg tcgagaatgg cgcgcgcgga gtcggcgatc
    20641 gggtcctgct ggtcgtcgcc ctcggcgagg acggtgtaga aggcggtgat cgagccgccg
    20701 ccctcggggc cgttgccggc gcgctcgacc agcgccggca ggcgggcgaa cacgctcggc
    20761 gggtagccgc gggtgaccgg cggttcgccg atcgcgagcg cgatctcgcg ctgggccatg
    20821 gcgtagcgcg tcagcgagtc catgatcagc agcacctggc ggccctgatc gcggaaatac
    20881 tcggccaccg tggtggcgta ggcggcgccc tgcatgcgca tcagcgggct ggtgtcggcg
    20941 ggggccgcca ccaccacaga gcgcgccagg ccctcggggc ccaggctgtg ctcgatgaat
    21001 tccttgacct cgcggccgcg ctcgccgatc agcccgacca cgatgatctc ggcctcggtg
    21061 tagcgcgcca tcatgccgat gagcaccgac ttgcccacgc ccgagccggc gaagaggccg
    21121 aggcgctggc cgcggccgac ggtgagcagc gcattgatcg cgcgcacgcc gacgtcgagc
    21181 ggctgcgcga tcggcgcgcg tgcgagcggg ttgatcgcgc gcccctgcag cgagcgcgtc
    21241 tcctgggtgt gcagcgggcc ctggccgtcg agcgggcggc ccgcgccatc gaccacgcgg
    21301 ccgagcaggg cgtcgcccac cggcaggtgc ttggcgcggt cggcggcgcg gcggcgcggg
    21361 ccgatgcgct tgccgggcac caggcgtggc acgcccacct ccatcggcag cacgcgcgca
    21421 cccggcgcca ggccgaagac gtcgtcggtg ggcatcatgt agagcttgtc gccgttgaag
    21481 ccgaccacct cggcctcgac cgcgccgccg ccgggcacca ggatgcggca gccggagccg
    21541 agcggcagct tgatgcccgc ggcctccatg accaggccgt tgatgcgggt gaggcgcccg
    21601 gaaacctcga gcgggttgca gccctcgacc aggcggcggc cgtcgccgag gaagtcgcgc
    21661 cacagcgcct ggtggcggtt catgccggcg gctccgcggc ggaggcgggc ggcgcaattc
    21721 cggccgcgga gggcgtgccg tcgggcgccg gagccgcgtc ctcgtcgtcc gtcacatgcc
    21781 agcgcgcgcg ctcgtggccg atggattcga gcacccgccg ccagcgcgtc tccagcgtcg
    21841 cgtccacctg cgcgccctgg ccgtcgatgc ggcattcgcc gcgttcgagg cgggcgtctt
    21901 cctgcaggcg gtggccggca tgggcgagct gttcgccaag atgctcgcgc accagggcga
    21961 gatcgtcggg gtggagctgg atgtgggcgt ggccctgggg cagctggagg agcgcgctgc
    22021 gcacggtctc gaggatggcc tcgggatgtt cggcgagggt gagcctgacc atccgccgcg
    22081 ccatctcgat cgccagcgcc atgagctgct cggcgatctc gccgtcgagc tcgcgcaagg
    22141 cctcgtcgag gctgtcggcg agtccggcca ggcgcgccgc ctcggcctcg gcctgcgcgc
    22201 gaccctcggc gtagccttcc gcacgcccgg cctccagccc ctcggcgtgg ccggccgcgc
    22261 ggccctcctc gaagcctgca cggcgcattt cgtcgtgcat gcgctcgatc tcctccgcgg
    22321 tgggcaggtg gaaatcgggc ggcagcgcgg gggcggcctc cgcggcgggc ggcggcgggg
    22381 cggcgtcgtg tgcgggcggg ggtgcgggcg agggcgccgg cgcggccggc atgtgcactg
    22441 cgggggaggg cgcattcagc gccgcgcctg cggggtccgt ggatgcgaag ccgtccgccg
    22501 ccggcgccga tcccgcagcg cccgcggggg cgtcgaagtc ctccggttcc cagcgccggt
    22561 aggcgccgac cgcctggtgc cgcgaaatgc tcaccgcagg ctcctcgcgt cgctacgcgg
    22621 acgccaggcc gggcggcgcc gggcagttcc tgtcgggcga cggggcgtgc gcatcctggt
    22681 gagcctgcgc acgcgggcgg cgcggggatc acacgaagcc atcgtcgcca cccttgccgc
    22741 cgagcatgac ctggccttcc tcggccaggc ggcgcaccgt cttgaggatc tccttctgct
    22801 cggcctcgac ctcggacagc cgcaccgggc cgcgcgcctc gaggtcctcg cgcagcatct
    22861 cggcggcgcg cgaggacatg ttcttgaaga ccttctcgcg cagctcgggc ggtgcgccct
    22921 tgagcgcgat gatcagcgag tcggactgga cctcgcgcag gatcgcctgg atgccgcggt
    22981 cgtcgacgtc gagcaggttc tcgaacacga acatctcgtc gaggatcttc tgcgccagct
    23041 ccggatcgta ttcacgcacg ttgtcgatga ccgcggtctc ggccgtcgag ccgacgaagt
    23101 tgaggatctc ggcggcgtgg cgcaccccgc ccatcgccgc cttcttgacc gtggtggcgc
    23161 ccgagagcat gcgggtgagg gcgtcgttga gctccttgag cgcggtcggc tgcacgccgt
    23221 cgagcgtggc gatgcgcagc accacgtcgt tgcgcaggcg gtcgtcgaag ttcttgagga
    23281 tctcgccggc ctggtcgtat tcgaggtgca ccaggatggt ggcgatgatc tgcgggtgct
    23341 cgcccttgat gaggtcggcc gcggtggccg cgtccatcca cttcaggctc tcgatgccgg
    23401 cggtctccga gccgctcatc atgcgcgaca gcagctggtt ggcacggtcg tcgccgagcg
    23461 ccttggtgag catctcgcgc agctggtcgt cgtcggactg gatcatcgtg cccttgccga
    23521 aatgctcgtt cacctcgatc agcaccggct ccacggtctc gcgcgactgc ggcgtcatcg
    23581 aggccatctt catcgtcagc ttctgcacct cgcgcgggcc gagctggcgg agcaccccgg
    23641 cggcagcgtc ggggccgagc gtcatcaaca gcagtgcggc cttctccagg ccttcttccg
    23701 gcgtcgtcac ttgcgcgcct cctcgttcaa gcccatccag tccctgatca ggttggcgac
    23761 catcttcgga tcgttgcgcg ccgcggtgcg cgcgcgctcg aggcgctgtt cgaaggtctc
    23821 cgtctcctcg ccctcgccgg cttcgccgga cagcgtgacg cgcacgcctt cctcgccttc
    23881 ctcgccctct tcgccttcct caccctcgcc ggcggccttc ttctcttcct tgctcttggg
    23941 cggcaccacc gtacgcagca gcggtcggat cacgccgaag taggcgaaca ggatcgcgac
    24001 cagcacgagc agccagttca ggccttcctt gccgagctcg atgatctccg ggtccttcca
    24061 cggcggcacc ggagcctcgc tgccgtcgtc ggcgaaggcg ccgctcgcca cgttgatggt
    24121 gtcgccgcgg tcggcgttgt agcccaccgc ctcgcgcacc aggttggtga tgcgggcgat
    24181 ctcctcgtcg ggcagcggca cgttggtggg cgtgccgtcg ggacccggga gggtgcgatt
    24241 attcaccacc accgcgaccg acaggcgctt gatctgcccg actgcctgct tgacgtgctg
    24301 gatgttgcgg tcgagctcgt agttgagcac cgcgctgcgg ttgccgctcg ccaggccctg
    24361 cgcgcccgcg ccgccggcca cctgcgggtt ggtgatcggc gcggtggccg gcaccggtgg
    24421 ctggttggtg agcgcgcccg gcacgccctg cgcgcccggc tgcgggttga aggcctcggt
    24481 ggtctgctgg ctgcggatgg cctggtcggg cgtggggttg ggcttgtagg tctcggcggt
    24541 ctgctcgacc tgattgaagt ccacatcggc cgccacctgg gcgccgtagt tgcccttgcc
    24601 caccaggggc gcgaggatct tgtcgatgcg ctcgatgaag ccctgctcga gcaggcggac
    24661 gtattcgagc tgggtggcgt tgagccccgc gcgcagcagc gggtcggcct gctcggtgag
    24721 cagcttgccg ttctggtcga cgatcttcac gccctcggcg tgcatgcgcg gcacgctcga
    24781 cgacaccagg tgcacgatgc cggcgacctg gtcgggcgac aggatgcggc cgccgcgcag
    24841 gttcaccatc accgacgcgg tggggcgctg gtcgtcgcgc aggaaggcgg tctgcttggg
    24901 catcgccagg tgcacccggg cgctggagac cgcgtcgatc gcctgcaccg tgcgggtgag
    24961 ctcgccttcg agcgcgcgct ggtagttcac ctgctcgttg aactgcgaga tgcccagctt
    25021 ctgcccgtcc atgagctcga agccggcgag gctgcccttg ggcaggccgt cggccgccag
    25081 gcgcagccgg gtctcgtgca cctgcgcctg cggcaccagg atggcgtggc cggtgggcga
    25141 catgcggtag gggatgttgc gctgctgcag ctcggcgatg atctgcccgc cgtcgcgctc
    25201 gtcgaggttg gagaacagca ccgcgtactc cggcgcgcgg ttccacagca gcgcgccggc
    25261 caccagggcg atcgccagcg cgaccgcgac cgcgccggcg atcttctgcc gggtgttcag
    25321 cgcggcgagg ttctgcagcg cctgctgcat gcgcgtcgcg gcctgcgcat cggcgggggc
    25381 ggcgcccgga ggcaggtctg cggtgttttc tgctgcggcc atgatggcgg tcctgttgct
    25441 tacgctttgg cggatggcgg cattgtgcgt ccgcgcgggc aagcgccagg gcgtgaaaag
    25501 cggcattttt tgccgcctgt ttgccggcta ccatggcggc ctgtgcattt agagtgcatc
    25561 ccgtgaaaac ggatccggac cttcccatgc aggccgcagt cgccgcccag gatcaagcag
    25621 ggagcatgcc cgtgggctcg gcggtcgatg ccgccgctgc ggcgccggtg ctcgacgccg
    25681 cccagctcgc cgaggccttc gcgctcttca gccgcgcctc cgaggagctg tccaccgcct
    25741 acgccgcgct gcaggcccag gtcggccagc tcagcgagcg cctttcggtg ctgatggggg
    25801 cgctgcccgc gggggtgctg gtggtcgatc gtgccggtac ggtggtgcag gccaaccgcg
    25861 ccgccgaggg gctcttcggc ggcgggctcg ccgggatggc ttgggcggcg ctcgccgccc
    25921 gcctggaaga cagcggcacc ccgggcgaat tcgtgctgcg ccgcgacccc gccacggtcg
    25981 acggcgacgc gcgccggctg gccttgtccg agtccgagct cgactccggc gccgagcgca
    26041 tcctgctggt gcacgacgtc accgacaccc atcgcatgcg cctcaccgcc gagcgcaacg
    26101 agcgcctcgc ggccatgggc gagatggtcg ccgggctcgc ccaccagctg cgcacgccgc
    26161 tcgccgccgc gctgctctac accggcaacc tgcgccagcc cgagctcgac ccggcgcagc
    26221 gcgccatggt cgccgaccgc gcgctcgaac gcctgcgcta tctcgagcgt ctgatccgcg
    26281 acatgctgct gttcgcccgc ggcgacagcg ccgggcgcca gcgcttcgcg gtgtgcgagc
    26341 tgctcgccga gctcgcgcac acgctcgagc cggtggcgcg cgcccgccag gtggccttcg
    26401 cggcggactg cggctgcggc gaggccgagc tggtcggcga ccgcaaggcg ctcggcggcg
    26461 cgctcaccaa cctgctcgag aacggcatcc aggcctgcga ggcgggcggc acgctgcgct
    26521 gcgaagcggc gctggtggct gccgccgacg ccggcatcgg cgcacccgcg gtgcgcttca
    26581 cggtgcgcga cagcggccgc ggcatcgccc ccgagctgca ggaacgcctc ttcgaaccct
    26641 tcttcaccac ccgcgccgaa ggcaccgggc tgggcctggc catcgcccgc ggcgtcgccc
    26701 gcgcccacgg cggcgacatc accctgcgct ccacgcccgg gcagggcgcg gaattcaccc
    26761 tggtcgtgcc gctggcggcg gcgcccaacg gtgcactaga gaacccatga tcgagaccct
    26821 caacatcctc gtcgtcgagg acgatgccgc gctccgcgac gcggtctgct tcacgctgga
    26881 gatggcgcac caccgcgtca ccggcgtcga tggcggcccg gcggcgctcg aagcgatcga
    26941 gcgcgagcac ttcaacctcg tcgtcaccga cctgcgcatg cagcccatgg acggcctgca
    27001 ggtgctgcac gaggtgcgcg cgcgccggcc gcagacgccg gtgctgctga tgaccgccta
    27061 cggcgacgtc gacaaggcgg tggcggcgat gcgcggcggc gcctgcgact tcctgatgaa
    27121 gcccttcgag cccgaggtgc tgctcgagag cgtgcgccgc tacgccgcgg tgcagcctgc
    27181 gggcgaggac accatcgccg aggatcccca cacccgcaac ctgctcgcgc tcgccgcgcg
    27241 cgtggccgag tccgacgcca cggtgatgct gtcgggcgag tccggcaccg gcaaggaagt
    27301 cttcgcgcgc tacctccacc agcactcgcc gcgcgccagg ggcccgttca tcgcgatcaa
    27361 ctgcgcggcc atccccgaga acctgctcga ggccacgctg ttcggctacg agaagggcgc
    27421 cttcaccggc gcgcaggcgg cgcagccggg caagttcgag caggctcagg gcggcaccat
    27481 cctgctcgac gagatctccg agatgccgct cgggcttcag gccaagctgc tgcgcgtgct
    27541 gcaggagcgc gaggtcgagc gcgtcggcgg caagaagccg gtggcgctgg acatccgcgt
    27601 gctggcgacg agcaaccgcg acatgctgaa agaggtcgct gccgggcgct tccgcgagga
    27661 cctgtattac cgcctcaacg tcttcccgat cgtcatcccg gcgctgcgcg agcgccccgg
    27721 cgacatcgtg ccgctggcgc gccacttcct cgcccgccac gccgcccgcc agcagcgcca
    27781 ggtgcgcttc tcgcccgcag ccgaggcgct gctgccgcag tacgcctggc cgggcaacgt
    27841 gcgcgagctg gagaacacca tgcatcgcgt gttgatcctg acccagggcg acgaggtcgc
    27901 cgccgagacc atccgcctgt g
//
LOCUS       DAOTIN010000037        27589 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_1985_length_27589_cov_9.193579, whole genome shotgun sequence.
ACCESSION   DAOTIN010000037 DAOTIN010000000
VERSION     DAOTIN010000037.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 27589)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 27589)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27589
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1985_length_27589_cov_9.193579"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..645
                     /locus_tag="P5537_07700"
     CDS             <1..645
                     /locus_tag="P5537_07700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein"
                     /protein_id="HRV77966.1"
                     /translation="LSQQVRHIEWIETAGEIGALLKEAELVKRLQPTHNRQLRRNREL
                     CTWRLATDIVGDWRLELMHAADLDFGRRDDLYGFFRTRREATNRLRALARDHALCPPL
                     LGLEKHPQGARCFDFQLKRCRGACHGGESPQAHALRLIEALHALKVEHWTWPGPIGLR
                     EGEAIHVVDGWRWLGTATDEATLADLLEAGRPAFDLDIYKILVKAVKRLAVVNL"
     gene            1085..1471
                     /locus_tag="P5537_07705"
     CDS             1085..1471
                     /locus_tag="P5537_07705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004316760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II truncated hemoglobin"
                     /protein_id="HRV77967.1"
                     /translation="MDQTTPYDTIGGEPVLAHLCDRFYGLMAETPRFAELRALHPEDL
                     QGSRDKLFMFLSGWLGGPDLFVQNFGHPRLRARHMPFAIGTRERDQWVACMLLAMEEV
                     GIAEPMRERLLQSFFKTADFMRNQPG"
     gene            1579..2499
                     /locus_tag="P5537_07710"
     CDS             1579..2499
                     /locus_tag="P5537_07710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004377574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HRV77968.1"
                     /translation="MTTPPPAQSDAVRGLLAALAVVVFWSGFNIVSRFGATASFTPFD
                     IAALRFGVSGAIALPLYLRFVPRRDWPRHMVLAAVAGLGYGILVYSGFAFAPSAHAGV
                     FVNGGIPFWTIVIMAVMSGFRIARPTVVALLLSTAGLLLIGFESLIAPTHGREWIGDL
                     LFLAAALCWAVFGLLMRRWQVKPQFGMLGIATFSALAYLPVYLLWLPGNLAAQGWGAI
                     ALQGVYQGVIAALVAGGFYSYAVQKVGASEASMMLALVPAVTAVGAFLILGEALGLIT
                     IVGIVVVSIGALLGALPPAALARMRGFGMR"
     gene            complement(2708..>3475)
                     /locus_tag="P5537_07715"
     CDS             complement(2708..>3475)
                     /locus_tag="P5537_07715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004316766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding domain-containing protein"
                     /protein_id="HRV77969.1"
                     /translation="AAAERRLRACRRSYTVELASFPWWWPDFAGGEGAALAHLARYFA
                     SDRPQHYKATRNGLSGVGFSSKFSPWLAQGALSPRVAFAALRRHEAAQGVSEGSYWLW
                     FELLWRDYFRFLHLQHGRRLYRARGLNAAAPPPAHDPAAFVAWCEGRTGHAFIDAGMR
                     ELAATGWLSNRMRQVVASFLIHDLGCDWRAGAAWFEAQLVDYDVYSNQGNWLYIAGRG
                     TDPRGGRRFDPDRQAATYDADGAYRTRWAELDRRGDD"
     assembly_gap    3476..3575
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<3576..4169)
                     /locus_tag="P5537_07720"
     CDS             complement(<3576..4169)
                     /locus_tag="P5537_07720"
                     /EC_number="4.1.99.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HRV77970.1"
                     /translation="MGSDVVIFRFRSDLRVGDNLALLEACASAGRLLPVYCHDPAADA
                     PTRWGFARRGPHRRAFLEAALDDLDAALRVRGSALLELHGAPCEVLPALARAVGTDAV
                     VCEAIAAPEEEDELAALRAAGLRVRTVWQSSLLDPAALPFAPARLPKVFTAFRQAVES
                     AGLQPPAPLPAAQTLPPWPDFATAAEAAHPIRACRRSY"
     gene            complement(4286..4432)
                     /locus_tag="P5537_07725"
     CDS             complement(4286..4432)
                     /locus_tag="P5537_07725"
                     /inference="COORDINATES: protein motif:HMM:NF021526.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2256 domain-containing protein"
                     /protein_id="HRV77971.1"
                     /translation="MQRKGDLPTKPCAGCGRPFAWRKKWARVWDEVRYCSERCRRERG
                     KPGR"
     gene            complement(4451..6037)
                     /locus_tag="P5537_07730"
     CDS             complement(4451..6037)
                     /locus_tag="P5537_07730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002925020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding domain-containing protein"
                     /protein_id="HRV77972.1"
                     /translation="MSYGLVWFKRDLRLADHAAFAAAARRGPVLCVLIVEPALWAHPD
                     AARQHYEFMLESARELHAELRRRGGRLHLLVGEAVAVLDRLYAAAPFDTLHSHEETGN
                     AASYARDRAVARWCRARGVRWHEPAQFGVVRRLDDRDRWQAAWEAHVAAPQAMPPEPS
                     RIAFAALPAALHPGAGTPWPQSGAIVAARAPEAVALGLDAFQPPRRLRGGRRAALEVL
                     HDFLDARSGQYRGGISSPLKAPTACSRLSPYLAWGCLSLREVVQASRARVATLPEGDR
                     RRAGLSAFLSRLYWHCHFIQKLESEPALEFRNLHRGYDGLREHDWNPAHFDALVAGRT
                     GWPLVDACVAMLRETGWINFRMRAMLVSVAAYPLWLHWREVGLWLARAFLDYEPGIHW
                     SQLQMQSGTTGINTTRVYNPIKQARDHDPNGVFVRRWLPALRRVPDTWLFEPWRMPAD
                     VAARHGLRLGEDIALPPVELETATRAAKARVHALRAEPEVRAAKAAIVERHGSRKRPE
                     GRRRKASASAASPGQLDLGF"
     gene            complement(6125..7117)
                     /locus_tag="P5537_07735"
     CDS             complement(6125..7117)
                     /locus_tag="P5537_07735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004386048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HRV77973.1"
                     /translation="MNVNPHIAVIGAGIAGLACSRSLADAGVRVTVLDKSRGPGGRTS
                     TRRGEGWACDHGAQYFTARHPEFIEELAAWRAAGVAAPWPARITVFDADGRRGLHGQE
                     ARFVGTPRMTAPARHLAQGLDLRVQLTVSALQRYPHGWEIATAERGMLPEAFDGVLLA
                     VPSPQAVPLLQPLSPALAAAAQAARMQACWALMARFDAPLAVDFDAAFVNHGPLRWIA
                     RDRSKPGRDGLETWSLHASAEWSEAHIEDTPERVALALVGAFEALGGRMPLGWAAHRW
                     RYAITESALDGGCAWDAAQALGVCGDWTNGGRVEGAWLSGRALARQVLDGLAAG"
     gene            7345..7806
                     /locus_tag="P5537_07740"
     CDS             7345..7806
                     /locus_tag="P5537_07740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3429 domain-containing protein"
                     /protein_id="HRV77974.1"
                     /translation="MNVPLPDSVRRTANRLGYAGLIPFVVLAPASLLDAHHGITWSDA
                     LFAYGAVILSFVCALHWGFAMALPGLDERRRVRTLLWSVVPSLIAWPALLLVPSDAAV
                     LLVLGFVLHYVQDRRFAREAGLPGWYLPLRLRLTTVACIALIAGTFVQWPY"
     gene            7860..9224
                     /locus_tag="P5537_07745"
     CDS             7860..9224
                     /locus_tag="P5537_07745"
                     /EC_number="2.7.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HRV77975.1"
                     /translation="MNTAASAIDPKHPVADAARSAAVPGGRLSRLARLGSLATGVAGG
                     MLAEGARQLAAGKRPKVSELVLTPANARRVAEQLAQLRGAAMKVGQLMSMDAGSLLPP
                     ELADILARLREDARTMPMSQVVQVLETHWGKGWEQGFERFSFTPCAAASIGQVHRART
                     RDGQELAIKLQYPGVRRSIDSDVDNVATLLRVSGLLPKSLDLAPLLAEAKRQLHEEAD
                     YRREAENLHRFGGLLGDAQDFVLPRAVDALTRSDILAMSWVEGVAVESLAEPQAADQV
                     LRDRVASLLIGLLFRELFEFRLIQTDPNFANYRFDAASGRLALLDFGATRPYAEPVVE
                     AYRRLMAGTVRGDRAAMGEAAQAIGYFQEHIHAAQRDAVIDLFATACEPLRHPGAYDF
                     GTSDLPLRLRDAGLKLSMERDFWHTPPADALFLHRKLGGLYLLAARLRARVDVAALAA
                     PWLE"
     gene            complement(9468..10664)
                     /locus_tag="P5537_07750"
     CDS             complement(9468..10664)
                     /locus_tag="P5537_07750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIST N-terminal domain-containing protein"
                     /protein_id="HRV77976.1"
                     /translation="MNPTRFAAGHAAHADWHVALARALDALLLELRAAGGHDHTGRDG
                     LPEYTLGFCYLSDPFAADADEIVAELQRRLPGVHWVGTVGIGVAATGAEHFDEPALVL
                     MLAPLPRRAFRVFSGVQPLRADAEDFHPHTALVHADGRTPDLQELLPELAERTASGYL
                     FGGLTASRGRSVQIADGVFDGGGLSGVAFSAEVGVISRVTQGCQPIGPRRLVSRARDN
                     FVITLDGRGALDCVMEDLGLPPDMALEPVAEALSNTLVGLHPGEDAEIVAPAAFGADM
                     LVRNIIGLDPRAGVVAIGDEVEQGGWLIFCRRDPAAALADLRRIAREIRDELVDSDRV
                     ALGAVYVSCSGRGGPHFGRPAAELELIRDVLGDVPLAGFFAGGEIAHSRLYGYTGVLT
                     VFAAAR"
     gene            complement(10661..11551)
                     /locus_tag="P5537_07755"
     CDS             complement(10661..11551)
                     /locus_tag="P5537_07755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004379688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HRV77977.1"
                     /translation="MHYTVRKPSSTERVSVRGLEYNVRRWGPADAPKVFLLHGWMDTS
                     ATFQFVVDALRHDWQLIAPDWRGYGETTWLHRPYWFPDYYADLEALLAHYAPEGPVRL
                     VGHSMGANIAGIYAGLRPQRVARLAMLDFIGLKVPADVDAPQQLGRWLDAQLVPPPAR
                     AYADRAALAARLRVANPRLTPARAEFLCRHLGRVRSDGQVEIAGDPWHKIPSPAVYRI
                     EDAMACWRLVRAPVLMLVSAEGYVHDRFADEPEELQRRIGCFANARVVTVPDCGHNLQ
                     HDQPEVVAAALEDFLDRETP"
     gene            11658..12419
                     /locus_tag="P5537_07760"
     CDS             11658..12419
                     /locus_tag="P5537_07760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2'-5' RNA ligase family protein"
                     /protein_id="HRV77978.1"
                     /translation="MTDPATLRRRFLAEPLTLRNERRDFPEWHRGRPHYLLWAIDTDL
                     AAVRARVVAAQRALDGLLLDGYRRQPHITLALCGFPARGAEPAVDEFDLAWLQARVAA
                     LEAARVAPFTLAIGGLESFSSAPFLHVGGALAALAALRACLHADAPHPQGAYVPHVTV
                     GLYADALPTAAVAPRFAACAAPPLHFTVERICLMRYAAAEIGGALSTLAEWDLAAHRL
                     HWRDASSSAALFAAGTLDRASRSAVPAAARHPEVS"
     gene            12416..13042
                     /locus_tag="P5537_07765"
     CDS             12416..13042
                     /locus_tag="P5537_07765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004388506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015109 - chromate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015703 - chromate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HRV77979.1"
                     /translation="MNPSPHGAAADAGTLSRPGSPFALFIAFSLLALQGFGGVLAVAQ
                     RELVDRRGWLSRAEFIELYSIAQMLPGPNVVNLSLMIGDRYFGWRGALAAITGMLLAP
                     FLIVIALAASYERLAEFPAVAGALRGMGAVAAGLILAMAVKMLGTLRGNLLGPWLCAL
                     LGLAALVAIAVFRLPLAWIVIGLGLLGWGLARWRVAVLDARAAHGEGR"
     gene            13039..13587
                     /locus_tag="P5537_07770"
     CDS             13039..13587
                     /locus_tag="P5537_07770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015109 - chromate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015703 - chromate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HRV77980.1"
                     /translation="MNTLPAGDLLALFLHFLTLSLLSIGGAMSTAPEMQRYFVVERGW
                     IGEADFTTAIALAQAAPGPNVLFVPVLGFQAAGLPGAAAALVGILLPSTLLSLGVSRW
                     GSSRRDTPLVRAFTAGLAPVTVGLVFATGWLLALPFLGDPAHRNGALVLIALTAVVTL
                     RTKLAPIWMILVGALLGAAGIA"
     gene            complement(13607..13990)
                     /locus_tag="P5537_07775"
     CDS             complement(13607..13990)
                     /locus_tag="P5537_07775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1850 domain-containing protein"
                     /protein_id="HRV77981.1"
                     /translation="MAVCLATSLASAAVAANAFTLAWTHSIERVRWEEAWRVEGEVLV
                     LERVRVRGHGAGMEPAAGAVLRDGAWEWHPHTRHAVLRLTRSAYTADYEWCVDGEPCK
                     PLSALIASDGGVTELRACPIGDTAR"
     gene            complement(13990..16023)
                     /locus_tag="P5537_07780"
     CDS             complement(13990..16023)
                     /locus_tag="P5537_07780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004381699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter permease"
                     /protein_id="HRV77982.1"
                     /translation="MSSSVDSPVAVAGKGMLRVVFYSAILFSVFQLVTSAFSPLSSTV
                     VRALHVGFLLLLTFLLHPWQGGQGRTRLATKAVGFGALLLSGYHWIYEADLVQRAGEL
                     TQADMAVGVITLVLVFEAARRIMGLALPLICLGFLAYALFGEYLPGDLAHRGYGLDQV
                     VGQLAFGTEGIYGTPTYVSSSYIFLFILFGAFLEQAGMIDLFTNFALGTVGHTKGGPA
                     KVSVVSSGLMGTINGSGVANVVTTGQFTIPLMKKFGYKPAFAGAVEATSSMGGQIMPP
                     VMGAVAFIMAETINVPYVEIAKAAAIPAMLYFFTVFWMVHLEAGRAGLKGLPKEECPD
                     PWVAIRARWYLLLPLAGLVYLLFAGFTPMFAGMVGLALTVVLLFGSSLARHLNGTSLR
                     LLFWIVLGLACSAFAKVGIISVVAVVAVLAVLLAPRADGRDTLRLAVRALVDGALHAL
                     PVGVACALVGVIIGSLTLTGGATAFAGYIIQIGDDSLFVSLLLTMLTCLVLGMGIPTI
                     PNYIITSSIAAPALLELGVPLIVSHMFVFYFGIMADLTPPVALAAFAAAPIAKETGLK
                     IGVRAVQIAIAGFIVPYMAVYAPELMLQGDKGFDATLYVVFKALLAVTLWGTAVVGYF
                     RSPMNPLERVLAFVAASMLVVALPITDELGFGLAAVVMGWHIWRSRGAQALTV"
     gene            complement(16100..17050)
                     /locus_tag="P5537_07785"
     CDS             complement(16100..17050)
                     /locus_tag="P5537_07785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TAXI family TRAP transporter solute-binding
                     subunit"
                     /protein_id="HRV77983.1"
                     /translation="MKSLIRKCALGTVFVAMTTAASAATFVNVLTGGTSGVYYPLGVT
                     LSQIYGEVIPGSKVQVQATKASAENLNLLQAGRGEIGFSLADSVSDAWKGNPDAGFTK
                     PLDKLRAIASVYPNYIQIVALADANVKTLADLKGKRISVGAPRSGTEINARAILKAAG
                     LSYSDFSKVEYLPFGESVELMKNRQIDVTLQSAGLGVAALRDLSAAVKVNFVPVPAEV
                     VAKVGDPAYRAAAVPANTYEGQAAEVPTVAINNLLVTNDKVSEEVAYQMTKGIFDNLE
                     RLGNSHSAGRQIKLEKAVDGLPVPLHPGAEKFYREKGLIK"
     gene            17187..18437
                     /locus_tag="P5537_07790"
     CDS             17187..18437
                     /locus_tag="P5537_07790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HRV77984.1"
                     /translation="MRASNRQQLRPGRVSPSSARRRRSATTASAQPFRPALTHASSRP
                     KPMETVDSVVIGAGVVGLACAHSLARAGLEVVVIERETAFGTGISARNSEVIHAGLYY
                     PPGSLKARLCVEGRQRLYAWCAQHGVDHARCGKLVVASAAAQAPALQAIAERAHANGV
                     DDLRRLDAAELAALEPALAGHAALLSPSTGIVDSHGLMLSLLGEAERHGALLALGSPV
                     LEGRAEADGIVLRIGGEAATELKAKRVVNAAGLDAPALGRAIAAPAAARAPQAHYARG
                     VYFSYAGKAPFSRLIYPIPEPGGLGVHLTLDLGGQAKFGPDVEWIAAPDYTVDPARVE
                     RFAGAIRRWWPDLDTERLQPGYAGVRPKIVGPGEPDADFRIDGPAAHGTPGLVHLYGI
                     ESPGLTAALAIGEHVAAMLAAEGR"
     gene            complement(18475..19776)
                     /gene="gabT"
                     /locus_tag="P5537_07795"
     CDS             complement(18475..19776)
                     /gene="gabT"
                     /locus_tag="P5537_07795"
                     /EC_number="2.6.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003867 - 4-aminobutyrate transaminase
                     activity [Evidence IEA];
                     GO_process: GO:0009450 - gamma-aminobutyric acid catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-aminobutyrate--2-oxoglutarate transaminase"
                     /protein_id="HRV77985.1"
                     /translation="MNANTIPPGLHNADFMARRAAALPRGVGQAHPLFATKALNAEVW
                     DVEGRRFIDFVAGIAVVNTGHCHPRVVAAAQAQLTHFSHTCFQVVAYDGYLRLAERLN
                     ALAPGDAPKKTMLVSTGAEAVENAVKIARAFTGRPGVIAFNGAFHGRTLLALGLTGKV
                     DPYKLGVGPFPGEIYHAPYPCALHDISVDDAIHGVELLFKNDIEARRVAAFIVEPVQG
                     EGGYYPAPAEFLQRLRALADKHGILLIADEIQSGIGRCGKMFAVEHSDVVPDLITLAK
                     GLGGGFPVAAVVGRAEVMDALAPGGLGSTYAGAPMACAAALAVLDVMEEEKLCERALA
                     IGEHMQRRLRELATRHKCIGDVRGLGAMVAVEFFHDGDHARPAPEIAKAVIAAALQRG
                     LLLLSCGSYGNVLRLMVPLTIEQAVLDEGLDLLAAAMDAAA"
     gene            complement(19814..21274)
                     /gene="gabD"
                     /locus_tag="P5537_07800"
     CDS             complement(19814..21274)
                     /gene="gabD"
                     /locus_tag="P5537_07800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009013 - succinate-semialdehyde
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_process: GO:0009450 - gamma-aminobutyric acid catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HRV77986.1"
                     /translation="MSLNLKDPDLFRTRCYVDGQWIDADDGATLSIRNPATGEALGTI
                     PRMGAAETRRAIEAANTAWPAWRALTAGARAKILRRWFELILANQEDLAVLMTSEQGK
                     PLAEARGEVLYAASFIEWFAEEGKRIYGDVIPGHQPDKRIVVTKEPIGVCAAITPWNF
                     PAAMITRKAGPALAAGCTMVLKPATQTPYSALALAVLAERAGIPKGVFSVVTGGAAEI
                     GGELTANPIVRKLTFTGSTEIGVKLMSQCAPSIKKLSLELGGNAPFIVFDDADLDAAV
                     EGALASKYRNTGQTCVCANRLLVQDGVYDAFAAKLAAAVARLKVGNGLAEGSTQGPLI
                     DMNAVAKVEEHIADAVEKGARVLAGGKRHALGGSFFEPTILVDVTPAMKVAREETFGP
                     VAPLFRFKDEAEAIRMANDTEFGLAAYFYASSMNRVWRVGEALEYGIVGINTGIISTE
                     VAPFGGMKSSGLGREGSKYGIEDYLEVKYLCMGGVQ"
     gene            complement(21352..22176)
                     /locus_tag="P5537_07805"
     CDS             complement(21352..22176)
                     /locus_tag="P5537_07805"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002944558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV77987.1"
                     /translation="MLQPYASPVERAWYFGMRGLVGLILAFLFLPILVIVPLSFNADS
                     FLMYPMSGFSLRWYEEFATSPAWRQALMNSLIVSPLATLLAMVLGTLASIGLVRADFP
                     GKALLTAVLISPMVVPVVVIGVAMYIFFAPLGLTGSYTGLVLAHAILGVPFVVTTVTA
                     TLQGFDFNLVRAASSLGANPVTTFFRVTLPMVAPGIISGGLFAFATSFDEVVVTLFLA
                     SPEQATLPRQMFAGIRENISPTIAAVATILIVLSTLMLMTLEWLRRRAERMRGARR"
     gene            complement(22188..23462)
                     /locus_tag="P5537_07810"
     CDS             complement(22188..23462)
                     /locus_tag="P5537_07810"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002944556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV77988.1"
                     /translation="MSTAVDTSAAVPLPAEGDGTPLKKRLRRAERRRNLLFGALILPL
                     ALVVLVAFIWPIGSLLTIGVDNPEIHDNLPRTLAVLEDWNGSAPPDEAAFRALADELA
                     AAKGSPAIAAIAKRLNRENAGYRSLVMKTARKLPLDAAVPAREALVAIDAQWGELATW
                     QAIHRAGGALTPFYLLAAIDRAIDADGDIVAAPEDERIYVDVLLRTFWMSLIVTVCCL
                     ALGFPVAYLMASLSTRHSNMLMIFVLLPFWTSVLVRVAAWIVLLQNEGLVNRLLMWLG
                     LTDSPLQLLFNRFGVYVAMVHILLPFMVLPLYSVMKGISPVYMRAALSLGCPPFRSFW
                     KIYFPQTLPGIGAGGLLVFIMCMGYYITPALLGGPKEQMLSYFIAFYTNQTINWGMAA
                     ALSAVLLAATLLLYMVYARYLGPTRVKYMKAR"
     gene            complement(23580..24620)
                     /locus_tag="P5537_07815"
     CDS             complement(23580..24620)
                     /locus_tag="P5537_07815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HRV77989.1"
                     /translation="MKHAASFLRAAVLVALGGAVGTASADITVISFGGASQKAQDKAY
                     YAPFAKATGVKVVAGEYNGEQAKVKAMVEAGNVTWDVLEVESPELVRGCEEGLFEKID
                     FAQVGDKADFVPAAVNECGVGIFVWSTALAYNADRLKEAPTSWADFWNVDKFPGKRGL
                     RKGAKYTLEFALLADGVPTSDVYKVLATPAGVDRAFAKLDKLKANIQWWEAGAQPPQL
                     LASGDLVMSAAYNGRISAAQVEGKNLKVVWNGSIYDVDSWAIPKGSPNKADALKFIRF
                     ASQPDNQAVFSGEIAYGPVNLKAVPAIDAKVAAGLPTSPENMTGAMATDTEFWVEHGE
                     NLEQRFNAWAAR"
     gene            complement(24708..25814)
                     /locus_tag="P5537_07820"
     CDS             complement(24708..25814)
                     /locus_tag="P5537_07820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV77990.1"
                     /translation="MEAVHNSQAPHVSFRNVQKTYDGETLIVRDLNLDIRRGEFLTLL
                     GPSGSGKTTCLMMLAGFETPTGGEIRLDGEVINRVPPYRRNIGMVFQNYALFPHMTVA
                     DNLRFPLRVRKLAANEVEARVKRALGMVQLEAFGNRYPQQLSGGQQQRIALARALVFD
                     PQLVLMDEPLGALDKNLRERMQLEIKHIQQNLGITVVFVTHDQSEALTMSDRIAVFNH
                     GVIQQIDAPEALYEYPTNSFVADFIGENNALDGTVVAVAGEECDVRLDCGTVLRARTG
                     NVGAGGRARIAVRPERVQLAGEGEGANRLDATVRELIYLGDQIRLRVELAGKHEFTIK
                     APISQLDRSLRPGDAIRVGLDPAHTRALDVPAAH"
     gene            25935..27419
                     /locus_tag="P5537_07825"
     CDS             25935..27419
                     /locus_tag="P5537_07825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HRV77991.1"
                     /translation="MDCRLSCELIVHAYAEQAPSSSARARLYLAIREAIIARRLAPGT
                     ALPPTRTLAAELALGRNTVVRVYDQLIVEGYLDSRVGSGTFVSDAVAATAPQQKPRRM
                     VGARSEGLSKRGCRIAADALSSRVQAGAFMPGFPDVTHFPFATWRKLVAKQMRLEQRH
                     LAQYGYGGYGPLKLVLAEYLRVTRMMSCSPQQILILNGSHQALDLCARMLADVGDVAW
                     MEDPGYWGARNVLSACDLAIHPVPVDGQGINPQEADWDHPPRLIFVSPSSQYPTGAVM
                     SLERRLRLLEYAEKNRIWIIEDDYDNEIRYHDHPVASLFGLSAAQRVIYVGTFSKVMY
                     PGLRLAYLVVPEDLVEAFTTGNAELYREGRMLEQAALAEFIDGGHFTTHIRRMRGIYE
                     ERRDRLIEVLQRHLAGIATPAGGLAGLHIPVHFECPLDDVLLATQALREGVVMRPLSL
                     YAIDATNRRPGMNLGFAAVPVEQIEAPALKLVRLIHGLLPAGSR"
     gene            complement(27491..>27589)
                     /locus_tag="P5537_07830"
     CDS             complement(27491..>27589)
                     /locus_tag="P5537_07830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HRV77992.1"
                     /translation="INKDPEAPIFQVADYGLVADLFEAVPALVAAA"
BASE COUNT         3964 a         9897 c         9766 g         3862 t
ORIGIN      
        1 ctcagccagc aggtgcgcca catcgaatgg atcgagaccg ccggcgagat cggcgcgctg
       61 ctgaaggaag ccgagctggt gaagcgcctg cagcccaccc acaaccgcca gctgcgccgc
      121 aaccgcgagc tgtgcacctg gcggctggcc accgacatcg tcggcgactg gcggctcgag
      181 ctgatgcacg ccgccgacct cgacttcggc cgccgcgacg acctctacgg cttcttccgc
      241 acccgccgcg aggccaccaa ccgcctgcgc gcgctcgccc gcgaccatgc cctgtgcccg
      301 cccctgctcg gcctggagaa acacccgcag ggcgcgcgct gcttcgactt ccagttgaaa
      361 cgctgccgcg gcgcctgcca cggcggcgaa tccccccagg cccacgccct gcgcctgatc
      421 gaggccctgc acgcgctgaa ggtcgagcac tggacctggc ccggcccgat cggcctgcgc
      481 gagggcgagg cgatccacgt cgtcgacggc tggcgctggc tcggcaccgc caccgacgag
      541 gccacgctcg ccgacctcct cgaagccggc cgcccggcct tcgacctcga catctacaag
      601 atcctcgtca aggcggtgaa aaggctggcg gtggtgaacc tgtaggaggc gcgccccacg
      661 gcgtgcgtgc cgacgtcggc cgccgcattc gcgcctgccg gcgctcctac atgaaccccg
      721 cggcttcgtc ccgcgcacca ccacctctcc ccccgccgca ttcgcgcctg ccggcgctcc
      781 tacatgaacc ccgcggctcc gtcccacgca ccgccgccgc tcccccgccg cattcgcgcc
      841 tgccggcgct cctacacgaa ccgcggggct tcgtcccacg caccgccgcc gctcccccga
      901 cgcattcgcg cctgccggcg ctcctacacg aaccgcgcgg cttcgtccca cgcaccgccg
      961 cgcttccgac cgatgtagga gcgccggcag gcgcgaatgc ggcgatcggg caggcggcgc
     1021 ccgagtctgc gacaatcctg gtcgaggcgc ccgtctcgaa gcgccaccga ccccacagac
     1081 cccgatggac cagaccaccc cctacgacac gatcggcggc gagcccgtac tcgcccacct
     1141 ttgcgaccgc ttctacggcc tgatggccga aacgccccgc ttcgccgagc tgcgcgccct
     1201 ccaccccgag gacctgcagg gctcgcgcga caagctcttc atgttcctct ccggctggct
     1261 cggcgggccg gacctcttcg tgcagaactt cggccacccg cgcctgcgcg cccgccacat
     1321 gcccttcgcc atcggcaccc gcgagcgcga ccaatgggtc gcctgcatgc tgctggcgat
     1381 ggaggaggtc ggcatcgccg agccgatgcg cgagcgcctg ctgcagagct tcttcaagac
     1441 cgccgacttc atgcgcaacc agccgggctg aacctgctcc cggtcgccca acgcgcaccc
     1501 ggccgcctcc gcccaggcac acgcagacgc agacgcagac gatcaacgtc gcccacccgc
     1561 acgctccccg gacccgaatt gaccactccc ccgcccgccc aatccgacgc cgtccgcggc
     1621 ctgctcgccg cgctcgccgt ggtggtgttc tggtccggct tcaacatcgt gtcacgcttc
     1681 ggcgccaccg ccagcttcac gcccttcgac atcgccgccc tgcgcttcgg cgtgtcgggt
     1741 gcgatcgcgc tgccgctcta cctgcgcttc gtgccgcgcc gggactggcc gcgccacatg
     1801 gtgctcgctg cggttgccgg gctgggctac ggcatcctgg tgtattccgg cttcgcgttc
     1861 gcaccgagcg cgcacgccgg cgtgttcgtc aatggcggca tcccgttctg gaccatcgtg
     1921 atcatggcgg tgatgagcgg ctttcgcatc gcccgcccca ccgtcgtcgc gctcctgctg
     1981 tcgaccgccg ggctgctgct gatcggcttc gagagcctga tcgcccccac gcacgggcgc
     2041 gaatggatcg gcgacctgct cttcctcgcc gccgcactgt gctgggcggt cttcggcctg
     2101 ctgatgcggc gctggcaggt caagccgcag ttcgggatgc tcggcatcgc caccttctcg
     2161 gcgctcgcct acctgccggt ctacctgctc tggctgccgg gcaatctggc cgcccagggc
     2221 tggggcgcga tcgcactcca gggcgtgtac cagggcgtga tcgccgccct ggtggccggc
     2281 ggcttctaca gctacgcggt gcagaaggtg ggcgcgagcg aagcctcgat gatgctggcg
     2341 ctggtgcctg ccgtcaccgc cgtgggcgcc tttctgatcc tgggcgaagc gcttggcctc
     2401 atcaccatcg tcggcatcgt ggtggtgtcg atcggcgccc tgctcggcgc gctgccgccc
     2461 gcggcactgg cacgcatgcg cggattcggc atgcgctgag cgccgggcag ggccgccccc
     2521 gcgcgcgggc gccccatgcg gatgagctcg gcttcggggt agcgcttgaa ctgcgctgcg
     2581 cgcgcgagcg ccccccggac gggccgccgt cgagcgatcc cgggcatggt cgcgacaagt
     2641 tcgaacggga ctcctgcaag ccgcggcgcg ttcgagcgag ggccagccgc cgaggcggct
     2701 tgcgcgctca atcgtcgccg cgccgatcga gctcggccca gcgggtccgg taggctccgt
     2761 ccgcgtcgta ggtcgccgcc tgccggtccg gatcgaagcg ccgcccaccg cgcgggtcgg
     2821 tgccgcggcc ggcgatgtac agccagttgc cctggttgct atacacgtcg taatccacca
     2881 gctgcgcctc gaaccacgcc gcgccggcgc gccagtcgca gccgaggtcg tggatgagga
     2941 agctggcgac cacctggcgc atgcggttcg acagccagcc ggtggcggcg agctcccgca
     3001 tgccggcgtc gatgaaggcg tggccggtgc gcccctcgca ccaggccacg aaggccgccg
     3061 gatcgtgcgc gggcggcggc gcagcggcgt tcagtccgcg cgcccggtac aggcggcggc
     3121 cgtgctgcag atgcaggaag cggaagtaat cccgccacag cagctcgaac cacagccagt
     3181 agctgccctc gctcaccccc tgcgcggcct cgtgccgccg cagcgccgcg aaggccaccc
     3241 gcggggacaa ggccccctgc gccagccagg gcgagaactt gctcgagaaa ccgacgccgc
     3301 tcaggccgtt gcgcgtcgcc ttgtagtgtt gcgggcgatc gctggcgaaa taacgtgcca
     3361 gatgcgcgag cgccgctccc tcaccgccgg cgaagtcggg ccaccaccac ggaaaggagg
     3421 ccagctccac cgtgtaggag cgccggcagg cgcgcaggcg gcgctcggct gcggcnnnnn
     3481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3541 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnngtagg agcgccggca ggcgcgaatg
     3601 gggtgcgcgg cttcggcagc ggtggcgaag tccggccacg gtggcagggt ctgcgctgcg
     3661 ggcaggggtg cggggggctg caggccggcg gactcgacgg cctggcggaa agcggtgaac
     3721 accttgggca ggcgggccgg cgcgaagggc agcgccgcgg ggtcgagcag gctcgactgc
     3781 cacacggtgc gcaccctcag ccccgcggca cgcagcgcgg cgagctcgtc ctcctcctcg
     3841 ggcgccgcga tcgcctcgca caccaccgcg tccgtgccca cggcgcgcgc gagcgccggc
     3901 agcacctcgc atggcgcgcc gtgcagctcc agcagcgcgc tgccgcgcac gcgcaaggcc
     3961 gcatccaggt cgtccagcgc cgcctccagg aaggcacgcc gatggggccc gcggcgggcg
     4021 aagccccaac gcgtcggtgc gtcggcggcg gggtcgtggc aatagaccgg caacaggcgg
     4081 ccggcggacg cgcacgcctc cagcagcgcg aggttgtccc ctacgcgcag gtcgctgcga
     4141 aacctgaaga tcaccacgtc cgaacccatc ggcactcccc cgcagaccaa ccgcggcgcc
     4201 gctttttcgc cgcggcacgc caccgcaatg tccctcgctc agcgccccgc ctttccgccg
     4261 cggcacgccg ctacgagacc ctcgctcagc gccccggctt gccacgctcc cgccgacagc
     4321 gctccgagca atagcgcacc tcgtcccaca cccgcgccca cttcttccgc cacgcgaacg
     4381 gccgcccgca gcccgcgcac ggcttcgtcg gcagatcgcc cttgcgctgc atcgccatcg
     4441 cccgctcccc tcagaacccc aggtccagct gccccggact cgccgcgctc gccgacgcct
     4501 tgcgccgccg cccctccggc cgcttgcgcg agccgtggcg ctcgacgatg gccgccttcg
     4561 ccgcgcgcac ctcgggctcg gcgcgcagcg catgcacgcg cgccttcgct gcgcgcgtgg
     4621 cggtctccag ctccaccggc ggcagcgcga tgtcctcgcc gaggcgcagc ccatggcgcg
     4681 cggccacgtc ggcaggcatg cgccagggct cgaacagcca ggtgtccggc acccgccgca
     4741 gcgccggcag ccagcgccgc acgaacacgc cattggggtc gtggtcgcgc gcctgcttga
     4801 tcgggttgta cacccgggtg gtgttgatgc cggtggtgcc ggactgcatc tgcagctggc
     4861 tccagtggat gccgggctcg tagtcgagga aggcacgcgc cagccacagg cccacctcac
     4921 gccagtgcag ccagagcgga taggccgcca ccgacaccag catcgcgcgc atgcggaagt
     4981 tgatccaccc cgtctcgcgc aacatcgcca cgcaggcgtc caccagcggc cagccggtgc
     5041 gcccggccac cagcgcgtcg aaatgcgccg ggttccagtc gtgctcgcgc aggccgtcgt
     5101 agccgcggtg caggttgcgg aactccagcg ccggctcgct ctcgagcttc tggatgaagt
     5161 ggcagtgcca gtacaggcgg ctgaggaagg ccgacaggcc ggcgcggcgg cggtcgccct
     5221 cgggcagcgt ggcgacgcgc gcgcggctgg cctgcacgac ctcgcgcagg ctgaggcagc
     5281 cccaggcgag gtagggcgac agtcgcgagc acgcagtcgg cgccttcagc ggcgaggaga
     5341 tgccgccgcg gtactggccg ctgcgcgcgt cgaggaagtc gtgcagcacc tccagcgccg
     5401 cccgccgccc gccgcgcagg cgccgggggg gctggaaggc gtcgaggccg agcgccaccg
     5461 cctccggcgc acgcgcggcg acgatcgcac ccgactgcgg ccagggcgtg ccagcgcccg
     5521 ggtgcagcgc cgcgggcagc gccgcgaagg cgatccgcga cggctccggc ggcatggcct
     5581 gcggcgcggc gacgtgcgcc tcccacgccg cctgccagcg gtcgcggtca tccaggcggc
     5641 gcaccacgcc gaactgcgca ggctcgtgcc agcgcacgcc gcgcgcccga caccagcgcg
     5701 ccaccgcgcg gtcgcgcgcg tagctcgcgg cgttgccggt ctcctcgtgc gaatgcaggg
     5761 tgtcgaaggg cgccgcggcg tacaggcgat cgagcaccgc gacggcctcg cccaccagca
     5821 ggtgcaggcg accgccgcgg cggcgcagct cggcgtgcag ctcgcgcgcg ctctcgagca
     5881 tgaactcgta gtgctggcgc gcggcgtcgg gatgcgccca cagcgcgggc tcgacgatca
     5941 gcacgcacag caccggcccg cgccgcgccg ccgcggcgaa ggcggcgtgg tcggcgaggc
     6001 gcaggtcgcg cttgaaccag accaggccgt agctcacggc gctcgcctcc ccctgcgcac
     6061 gcgggcaggg atgctcgcgg gccaggccag gatcgaccgc ggcggtgcgt tcatgcgcgc
     6121 acgctcagcc cgcggcgagg ccgtcgagca cctggcgcgc gagcgcgcgg ccgctcagcc
     6181 aggcgccctc gacgcggccg ccgttggtcc agtcgccgca cacgcccagg gcctgtgcgg
     6241 cgtcccaggc gcagccgccg tcgagcgccg actcggtgat cgcgtagcgc cagcggtgcg
     6301 ccgcccagcc cagcggcatg cgcccgccga gcgcctcgaa ggcacccacc agcgcgaggg
     6361 cgacacgttc gggggtgtcc tcgatgtggg cctcgctcca ctccgcgctg gcgtgcagcg
     6421 accaggtctc cagcccgtcc cgccccggct tggagcggtc gcgtgcgatc cagcgcagcg
     6481 gcccgtgatt gacgaaggcg gcatcgaaat ccaccgccag tggggcatcg aagcgcgcca
     6541 tcagcgccca gcaggcctgc atccgcgccg cctgcgccgc cgcggcgagc gcgggcgaca
     6601 ggggctgcag cagcggcacc gcctgcggcg agggcaccgc gagcagcacg ccgtcgaagg
     6661 cctcgggcag catcccgcgc tcggcggtgg cgatctccca gccgtgcggg tagcgctgca
     6721 gcgcgcttac cgtgagttgc acgcgcaggt ccaggccctg ggcgagatgg cgggcgggcg
     6781 cggtcatgcg cggagtgccg acgaagcgcg cctcctggcc gtgcaggccg cgccggccgt
     6841 cggcgtcgaa cacggtgatg cgcgccggcc acggcgccgc caccccggcc gcccgccagg
     6901 ccgcgagctc ctcgatgaac tccgggtggc gcgcggtgaa gtactgcgcg ccgtggtcgc
     6961 aggcccagcc ctcgccgcgg cgggtgctgg tgcgcccacc cggcccgcgg cttttgtcga
     7021 ggacagttac gcgaactccg gcgtcggcga ggctgcgcga gcaggccaga ccggcgatcc
     7081 cggcgccgat gactgcaata tgtggattga cgttcatgag cgatccgggg gacgggagga
     7141 gttggacaga aacccgaata tactcttttt tgtcctggac aaaaaaggat cggcttcata
     7201 agatgaagca gacggggcaa tgccgggcca cgttcggctg gcagcaccgg gcggctccgc
     7261 ccgcccgacg ctcggcctcg ccgagtgccc ctcggtccgc catccactgc acccacccga
     7321 ttcctcttcc cgcgagccgc gaccatgaac gtcccgcttc ccgactccgt ccgccgcacc
     7381 gccaaccggc tcggctacgc cggcctgatc cccttcgtgg tgctcgcccc cgccagcctg
     7441 ctcgacgccc accacggcat cacctggagc gacgcgctgt tcgcctacgg cgcggtgatc
     7501 ctcagcttcg tgtgcgcgct gcattggggc ttcgccatgg cgctgcccgg gctggacgag
     7561 cgccggcggg tgcgcaccct gctgtggagc gtggtgccct cgctgatcgc ctggccggcg
     7621 ctgctgctgg tgccctccga cgccgcggtg ctgctggtac tcggcttcgt gttgcactac
     7681 gtgcaggacc gcaggttcgc gcgtgaggcc ggcctgcccg ggtggtacct gccgctgcgc
     7741 ctgcgcctca ccaccgtcgc ctgcatcgcc ctgatcgccg gcaccttcgt gcagtggccg
     7801 tactgaagac cacgcacgcg caaccgagcc cgccccgcac gcccaccgag gaacacgcca
     7861 tgaacaccgc agccagcgcc atcgacccca agcaccccgt cgcggatgcc gcacgcagcg
     7921 ccgcggtgcc cggcggacgc ctgtcccgtc tcgcccgcct gggcagcctg gccaccggcg
     7981 tggcgggcgg catgctcgcc gagggcgcgc gccagctcgc cgccggcaag cgccccaagg
     8041 tgagcgaact ggtgctcacc ccggccaacg cccgccgcgt cgccgagcag ctcgcgcagc
     8101 tgcgcggcgc ggcgatgaag gtgggccagc tgatgtcgat ggacgccggc agcctcttgc
     8161 cgcccgagct cgccgacatc ctcgcccgcc tgcgcgagga cgcgcgcacc atgccgatga
     8221 gccaggtggt gcaggtgctg gagacgcact ggggcaaggg ctgggagcag ggcttcgagc
     8281 gcttctcctt caccccgtgc gcggcggcct cgatcggcca ggtgcatcgc gcgcgcaccc
     8341 gcgacggcca ggagctggcg atcaagctgc agtatcccgg cgtgcggcgc agcatcgaca
     8401 gcgacgtgga caacgtcgcc acgctgctgc gcgtctccgg cctgctgccg aaatcgctcg
     8461 acctcgcgcc gctgctcgcc gaggccaagc gccagctcca cgaggaagcc gactaccgcc
     8521 gcgaggccga gaacctgcac cgcttcggcg gcctgctcgg cgacgcgcag gatttcgtgc
     8581 tgccgcgcgc ggtagatgcg ctcacgcgca gcgacatcct ggcgatgagc tgggtcgagg
     8641 gcgtcgcggt ggaatcgctc gcagagccgc aggcggccga ccaggtgctg cgcgaccgcg
     8701 tggcgagcct gttgatcggg ctgctgttcc gcgagctgtt cgagttccgc ctgatccaga
     8761 ccgaccccaa cttcgccaac taccgcttcg acgccgccag cggccgcctc gcgctgctcg
     8821 acttcggcgc cacccggccc tacgccgagc cggtggtcga ggcctaccgc cgcctgatgg
     8881 cgggcacggt gcgcggcgac cgcgccgcga tgggcgaggc ggcgcaggcg atcggctatt
     8941 tccaggagca catccacgct gcccagcgcg acgcggtcat cgacctcttc gccaccgcct
     9001 gcgagccgct gcgccacccc ggcgcctacg acttcggcac cagcgacctg ccgctgcgcc
     9061 tgcgcgacgc cgggctcaag ctgagcatgg agcgcgattt ctggcacacc ccgccggccg
     9121 acgcgctctt cctccaccgc aagctcggcg gcctgtacct gctcgcggca cggctgcgcg
     9181 cacgcgtgga cgtggccgcg ctggcggcgc cgtggctgga gtaagtacgc gcagaaagcc
     9241 tggcggcagc aagggttcgc ggctgccgcc gctcctgcac gctccgccgc tcggtggccc
     9301 tgtaggagcg ccggcaggcg cgaaggtggc ggtgccgcgg cgccggcgcg acttccgagt
     9361 gccgtcttcg cggctgccgc cgctcctaca ggagggcgag gcacggtgtt tcatgcagga
     9421 gcgccggcag gcgcgaacgc ggcatccgcg atcgcgaccc gcgcctgcta gcgcgccgcg
     9481 gcgaacaccg tgagcacgcc ggtgtagccg tacagccggc tgtgggcgat ctcgccgccg
     9541 gcgaagaagc ccgccagcgg cacgtcgccg agcacgtcgc ggatcagctc gagctcggcc
     9601 gccgggcgcc cgaagtgcgg gccgccgcgg cccgagcagc ttacatacac cgccccgagc
     9661 gcgacacgat cgctgtccac cagctcgtcg cggatctcgc gcgcgatgcg gcgcaggtcg
     9721 gcgagcgccg cagccgggtc gcgccggcag aagatcagcc acccaccctg ctcgacctcg
     9781 tcgccgatcg ccaccacccc tgcgcgcggg tcgaggccga tgatgttgcg caccagcatg
     9841 tcggcgccga aggcggcggg ggcgacgatc tccgcatctt cgcccggatg cagcccgacc
     9901 agggtgttcg acaaggcctc ggcgaccggc tccagcgcca tgtcgggcgg caggccgagg
     9961 tcctccatca cgcagtcgag cgcaccgcgg ccgtccaggg tgatgacgaa gttgtcccgg
    10021 gcgcggctca ccagccgccg cggcccgatc ggctggcagc cctgggtgac gcgcgagatc
    10081 acgccgacct cggcggagaa cgccaccccc gacaggccgc cgccgtcgaa gaccccgtcg
    10141 gcgatctgca cgctgcgccc gcgcgaggcg gtcagtccgc cgaagaggta gccgctcgcg
    10201 gtgcgctcgg cgagctcggg cagcagttcc tgcaggtcgg gcgtgcgccc gtcggcatgc
    10261 accagcgccg tatgggggtg gaagtcctcg gcgtcggcgc gcagcggctg cacccccgag
    10321 aacacgcgga aggcgcgccg cggcaggggc gcgagcatga gcacgagcgc cggctcgtcg
    10381 aagtgttcgg cgccggtcgc ggccaccccg atgcccacgg tgcccaccca gtgcacgccg
    10441 ggcaggcggc gctgcagctc ggcgacgatc tcgtcggcgt cggcagcgaa gggatcgctc
    10501 aggtagcaga agccgagggt gtattcgggc agcccgtccc gccccgtgtg gtcgtggcct
    10561 cccgcggcac gcagttcgag cagcagggca tcgagcgcgc gcgcgagcgc cacgtgccag
    10621 tcggcgtggg cggcgtgtcc ggcggcgaag cgggtcgggt tcatggggtc tcccggtcga
    10681 ggaaatcttc cagcgcggcc gccaccacct cgggctggtc gtgctgcagg ttgtggccgc
    10741 aatcgggcac ggtgacgacg cgggcgttcg caaagcagcc gatgcggcgc tgcagttcct
    10801 ccggctcgtc ggcgaagcgg tcgtgcacat agccctcggc ggagaccagc atcagcaccg
    10861 gggcgcgcac gagccgccag cacgccatcg cgtcctcgat gcggtagacc gcgggcgagg
    10921 ggattttgtg ccagggatcg ccggcgatct cgacctggcc gtcgctacgc acgcgaccga
    10981 ggtggcggca gaggaactcc gcacgcgccg gggtgaggcg tggattggcg acgcgcagcc
    11041 gcgcggcgag cgcggcccgg tcggcgtagg cgcgcgccgg cggcggtacg agctgggcgt
    11101 cgagccagcg cccgagctgc tgcggcgcgt cgacgtcggc gggtaccttg agcccgatga
    11161 agtcgagcat cgccagccgc gccacgcgct gcgggcgcag gccggcgtag atgccggcga
    11221 tgttggcgcc catgctgtga ccgaccaggc gcaccgggcc ctcgggcgcg tagtgcgcga
    11281 gcagggcctc gaggtcggcg tagtagtcgg ggaaccagta gggccgatgc agccaggtgg
    11341 tctcgccgta gccgcgccag tcgggggcga tcagctgcca gtcgtggcgc agcgcatcga
    11401 cgacgaactg gaaggtggcg gaggtatcca tccagccgtg cagcaggaag accttcggcg
    11461 catcggccgg accccagcgc cgcacgttgt attcgaggcc gcggacggaa acgcgttcgg
    11521 tggaggaggg cttgcggacg gtgtagtgca tgcgggcggg cgtcttttcc gggacaatca
    11581 cgcttccatt ctagccgccg attccatccc gccaccgtcc gtccggcatc gctgcggacc
    11641 tcaccccgcg ctcccgcatg accgatcccg ccacgctgcg ccgacgcttt ctcgccgagc
    11701 cgctgaccct gcgcaacgaa cgccgcgact tcccggagtg gcatcgcggc cggccgcact
    11761 acctgctgtg ggcgatcgat acggacctgg cggccgtacg tgcgcgcgtc gtcgccgcgc
    11821 agcgcgcgct cgacgggctg ctcctcgacg gctaccgccg ccagccgcac atcacgctgg
    11881 cgctgtgcgg ctttccggcg cgcggcgcgg agccggccgt ggacgagttc gacctcgcct
    11941 ggctgcaggc ccgcgtcgcg gcgctggaag cggcgcgggt cgcgcccttc acgctcgcca
    12001 tcggcggcct ggagagcttc tcgtcggcgc ccttcctgca tgtgggcggc gccctcgctg
    12061 cgctcgcggc gctgcgtgcc tgcctgcacg cggacgcacc gcacccgcag ggcgcgtacg
    12121 tgccgcacgt gaccgtgggc ctgtacgccg acgccctgcc caccgccgcg gtcgcgcccc
    12181 gcttcgccgc ctgcgccgcg ccgccgctgc acttcacggt cgagcgcatc tgcctgatgc
    12241 gctacgctgc cgccgagatc ggcggcgccc tgtccaccct ggccgagtgg gacctcgcgg
    12301 cgcaccgcct gcactggcgg gacgcttcgt catcggccgc gctcttcgcc gccggcacgc
    12361 tggatcgcgc aagccgcagt gccgtgccgg cagcggcccg ccatccggag gtctcatgaa
    12421 cccatcgccc cacggcgcgg cagccgacgc cggcacactc tcccgccccg gctcgccctt
    12481 cgcgctcttc atcgccttca gcctgctcgc gctgcagggc ttcggcggcg tgctcgcggt
    12541 cgcgcagcgc gagctggtcg accgccgcgg ctggctgagc cgcgccgagt tcatcgagct
    12601 gtattcgatc gcacagatgc tgcccggacc caatgtggtc aacctgtcgc tgatgatcgg
    12661 cgaccgctac ttcggctggc gtggcgcgct cgccgccatc accggcatgc tgctcgcgcc
    12721 cttcctgatc gtgatcgcgc tcgccgcgag ctacgagcgc ctggcggagt tccccgcggt
    12781 cgccggcgcg ctgcgcggca tgggcgcggt ggcggcgggg ctgatcctgg cgatggcggt
    12841 gaagatgctc ggcaccctgc gcggcaacct gctcggcccc tggctgtgcg ccttgctcgg
    12901 cctcgccgcg ctggtggcga tcgcggtgtt ccgcctgccg ctggcgtgga tcgtgatcgg
    12961 cctcggcctg ctcggctggg gcctagcgcg ctggcgggtg gcggtgctcg acgcgcgcgc
    13021 cgcgcatggg gagggacgat gaacacgctg ccggcgggcg acctgctcgc gctcttcctg
    13081 cacttcctga ccctgtcgct gctgtcgatc ggcggcgcga tgtcgaccgc gcccgagatg
    13141 cagcgctact tcgtggtcga gcgcggctgg atcggcgagg ccgacttcac caccgcgatc
    13201 gcgctcgccc aggcggcgcc cgggcccaac gtgcttttcg tgccggtgct cggcttccag
    13261 gccgccggcc tgcccggcgc cgcggcggcg ctggtgggca tcctgctgcc gtcgacgctg
    13321 ctctcgctgg gggtgagccg ctggggctcg agccggcgcg acacgccgct ggtgcgcgcg
    13381 ttcaccgccg ggctcgcgcc cgtcaccgtg ggcctggtgt ttgccaccgg ctggctgctc
    13441 gccctgccct tcctcggcga cccggcgcac cgcaacggcg cgctggtgct gatcgcgctg
    13501 accgcggtgg tgacgctgcg gacgaagctg gcaccgatct ggatgatcct ggtcggcgcg
    13561 ctgctgggcg ccgcgggcat cgcctgagga gcgccgcggg ggcggctcag cgcgcggtgt
    13621 cgccaatcgg gcaggcgcgc agctcggtga cgccgccatc ggaggcgatg agcgcggaca
    13681 agggcttgca gggctcgccg tccacacacc actcgtagtc ggccgtatag gccgagcgcg
    13741 tgaggcgcag cacggcgtgg cgggtgtgcg ggtgccactc ccaggcgcca tcgcgcagca
    13801 ccgcgcctgc cgccggctcc atgccggcgc cgtggccgcg cacgcgcacg cgctcgagca
    13861 ccagcacctc gccttccacc cgccacgcct cctcccagcg cacgcgctcg atcgagtgcg
    13921 tccacgccag ggtgaaggcg ttcgcggcaa ccgccgcgct ggcgaggctg gtggcgaggc
    13981 agaccgccat cagacggtga gcgcctgcgc gccgcgcgag cgccagatgt gccagcccat
    14041 caccaccgcc gccaggccga agccgagctc gtcggtgatc ggcagcgcga ccaccagcat
    14101 cgacgcggcg acgaaggcga gcacgcgctc gagcgggttc atcggcgagc ggaagtagcc
    14161 gaccaccgcg gtgccccaca gcgtgaccgc gagcaaggcc ttgaacacca cgtacaaggt
    14221 ggcgtcgaag cccttgtcgc cctgcagcat gagctcgggg gcatacaccg ccatgtaggg
    14281 cacgatgaag ccggcgatgg cgatctgtac cgcgcgcacg ccgatcttga ggccggtctc
    14341 cttggcgatc ggcgccgcgg cgaaggcggc gagcgcgacc ggcggggtga ggtcggccat
    14401 gatcccgaaa tagaacacga acatgtgcga gacgatcagc ggcacgccga gctcgagcag
    14461 cgcgggcgcg gcgatcgagc tggtgatgat gtagttcggg atggtcggga tgcccatgcc
    14521 gagcaccagg caggtgagca tggtgagcag cagcgagacg aacaggctgt cgtcgccgat
    14581 ctggatgatg tagccggcga aggcggtggc gccaccggtc agcgtcagcg agccgatgat
    14641 cacgcccacc agcgcgcacg ccacgcccac cggcagcgcg tgcagcgcgc cgtccaccag
    14701 ggccctgacc gccaggcgca gggtgtcgcg gccgtcggca cgcggcgcca gcagcacggc
    14761 gagcaccgcc accacggcga ccaccgagat gatcccgacc ttggcgaagg ccgagcaggc
    14821 caggccgagc acgatccaga acagcaggcg cagcgaggtc ccgttgagat ggcgtgccag
    14881 gctgctgccg aacagcagca ccacggtcag cgccaggccc accatgccgg cgaacatcgg
    14941 cgtgaagccg gcgaagagca ggtacaccag gccggcgagc ggcagcagca ggtaccagcg
    15001 cgcgcggatc gccacccagg ggtcggggca ctcctccttg ggcaggccct tcagcccggc
    15061 gcggccggcc tcgaggtgca ccatccagaa cacggtgaag aagtacagca tcgccgggat
    15121 cgccgccgcc ttggcgatct cgacgtaggg cacgttgatg gtctcggcca tgatgaaggc
    15181 caccgcgccc atcaccggcg gcatgatctg cccgcccatc gagctggtgg cctcgaccgc
    15241 gccggcgaag gccggcttgt agccgaactt cttcatcagc gggatggtga actggccggt
    15301 ggtgaccacg ttggccacgc ccgagccgtt gatcgtgccc atcaggccgg acgacaccac
    15361 cgacaccttg gccggcccgc ccttggtgtg gccgacggtg ccgagcgcga agttggtgaa
    15421 caggtcgatc atgcccgcct gctcgaggaa ggcgccgaac aggatgaaca ggaagatgta
    15481 ggacgaggac acataggtcg gcgtgccgta gatgccctcg gtgccgaagg cgagctggcc
    15541 caccacctga tcgaggccgt agccgcggtg ggcgaggtcg cccggcaggt actcgccgaa
    15601 cagggcgtag gcgaggaagc cgaggcagat cagcggcagc gccagcccca tgatgcggcg
    15661 cgcggcctcg aagaccagca ccagcgtgat gacgccgacc gccatgtcgg cctgggtgag
    15721 ctcgcctgcg cgctgcacca ggtcggcctc atagatccag tgatagcccg acagcagcag
    15781 tgcgccgaag ccgaccgcct tggtcgccag gcgggtgcgc ccctgcccgc cctgccaggg
    15841 atggagcagg aaggtcagca gcagcaggaa gccgacgtgc agcgcgcgta cgaccgtgct
    15901 cgacagcggg ctgaacgccg aggtgacgag ctggaagacc gagaacagga tcgcgctgta
    15961 gaagacgacg cgcagcatgc ccttgccggc cacggcgaca ggcgaatcga cggaggagct
    16021 catggcggtt ccggagaggg aagcggggca cggcccgccc gggcgcggcg atgcgcaacc
    16081 gggcggcgga agcgagggct tacttgatca gacccttctc gcggtagaac ttctcggcgc
    16141 ccggatggag cgggaccggc aggccgtcga ccgccttctc gagcttgatc tggcgaccgg
    16201 cggagtgcga attgcccagc cgctcgaggt tgtcgaagat gcccttggtc atctggtagg
    16261 cgacctcctc ggagaccttg tcgttggtca ccagcaggtt gttgatcgcc accgtcggca
    16321 cctcggccgc ctggccctcg taggtgttgg ccggaacggc ggccgcacgg taggcggggt
    16381 cgcccacctt ggcgaccacc tcggccggca cgggaacgaa gttcaccttc accgccgcgg
    16441 agaggtcgcg cagcgcggcc acgccgaggc cggccgactg cagggtgacg tcgatctggc
    16501 ggttcttcat gagctcgacc gactcaccga agggcagata ctcgaccttg gagaagtcgg
    16561 aatacgacag ccccgcggcc ttgaggatgg cgcgcgcgtt gatctcggta ccggagcgcg
    16621 gcgcgccgac cgagatgcgc ttgcccttga gatcggcgag cgtcttcacg ttggcgtcgg
    16681 ccagcgccac gatctggatg tagttggggt agaccgaggc gatcgcgcgc agcttgtcga
    16741 gcggcttggt gaagcccgca tccggattgc ccttccaggc gtcggagacc gagtcggcga
    16801 gcgagaagcc gatctcgccg cggcccgcct gcagcaggtt gaggttctcg gcggaggcct
    16861 tggtggcctg cacctggacc ttgctgccgg ggatgacctc gccatagatc tgcgacaggg
    16921 tgacgccgag cgggtagtac accccgctgg tgccgccggt cagcacgttg acgaaggtgg
    16981 cggccgaggc cgcggtggtc atggcgacga acacggtacc gagggcacac ttgcggatca
    17041 gggacttcat cgatgactcc tccattgaat aagtttcgat aatctgccca tcgatggacg
    17101 gccacacttt aacaacaccc ccgcccgcag cgcaccacca cggcgctcgg cgttttccct
    17161 gatagccgaa cgcgcccggc cgccatttgc gggcgtcgaa tcgccagcag ctgcggcccg
    17221 gcagggtctc cccctcttcc gcgcgacgtc ggcgatctgc tacaacggcc tctgcgcaac
    17281 ccttccggcc ggcgctcaca cacgcgtcca gccgtcccaa gcccatggaa acagtcgata
    17341 gcgtcgtgat cggcgccggc gtggtcggcc tcgcctgcgc acacagcctc gcccgcgccg
    17401 gcctcgaggt ggtggtcatc gagcgcgaga ccgccttcgg caccggcatc agcgcacgca
    17461 acagcgaggt gatccacgcc gggctgtact acccgcccgg ctcgctcaag gcccgcctgt
    17521 gcgtggaggg ccgccagcgc ctgtacgcct ggtgcgcaca gcacggggtg gaccacgcgc
    17581 gctgcggcaa gctggtggtc gccagcgccg cggcgcaggc accggcgctg caggcgatcg
    17641 ccgagcgcgc gcacgccaac ggcgtggacg acctgcgccg cctcgacgcc gccgagctcg
    17701 ccgcgctgga gccggcgctc gccggccacg ccgcgctgct gtcgccctcg accggcatcg
    17761 tcgacagcca cggcctgatg ctgtccctgc tcggcgaggc cgagcgccac ggcgcgctgc
    17821 tcgcgcttgg cagcccggtg ctggagggcc gcgcggaggc ggacggcatc gtgctgcgca
    17881 tcggcggcga ggccgccacc gagctgaagg cgaagcgggt ggtgaatgcc gcggggctgg
    17941 acgcacccgc gctcgggcgc gcgatcgccg cccccgcagc cgcgcgcgcc ccacaggcgc
    18001 attacgcgcg cggggtgtat ttcagctacg ccggcaaggc accgttctcg cgcctgatct
    18061 acccgatccc ggagccgggc gggctgggcg tgcacctgac cctggacctg ggcgggcagg
    18121 cgaagttcgg ccccgacgtg gaatggatcg ccgcaccgga ctacacggtc gatcccgcgc
    18181 gggtggagcg cttcgccggc gcgatccggc gctggtggcc ggacctcgac acggagcgcc
    18241 tgcagccggg ctatgccggc gtgcgcccga agatcgtcgg ccccggcgag ccagacgccg
    18301 acttccgcat cgacggcccg gcggcgcatg gcacgccggg gctggtacat ctgtacggca
    18361 tcgagtcgcc cggcctcacc gcggcgctcg cgatcggcga gcatgtcgcg gcgatgctcg
    18421 ccgccgaagg gcgctgaatc cgcagcgccc ttcggctcac ggacgcgagc ccgatcaggc
    18481 cgcggcgtcc atcgccgcgg cgaggaggtc gaggccttcg tcgagcaccg cctgctcgat
    18541 ggtgagcggc accatcaggc gcagcacgtt gccgtagctg ccgcaggaca gcagcagcag
    18601 gccgcgctgc agcgccgcgg cgatcaccgc cttggcgatc tcgggcgcag gacgcgcgtg
    18661 gtcgccgtcg tggaagaact ccaccgccac catcgcgccc aggccgcgca cgtcgccgat
    18721 gcacttgtgg cgcgtggcca gctcgcgcag gcggcgctgc atgtgctcgc cgatcgcgag
    18781 cgcgcgctcg cacagcttct cctcctccat gacgtcgagg acggcgagcg cggcggcgca
    18841 ggccatcggc gcgccagcgt aggtgctgcc cagcccgccc ggagcgagcg cgtccatcac
    18901 ctcggcgcgg cccaccaccg cggcgaccgg gaagccgccg ccgaggccct tggccagggt
    18961 gatgaggtcg ggcaccacgt cgctgtgctc gaccgcgaac atcttgccgc agcggccgat
    19021 gccggactgg atctcgtcgg cgatcagcag gatgccatgc ttgtcggcga gcgcacgcag
    19081 gcgctgcagg aactcggcag gagcggggta gtagcccccc tcgccctgca ccggctcgac
    19141 gatgaaggcg gcgacgcggc gggcctcgat gtcgttcttg aacagcagct cgacgccatg
    19201 gatggcgtca tccacgctga tgtcgtgcag cgcgcacgga tagggggcgt ggtagatctc
    19261 ccccgggaag gggccgacgc cgagcttgta ggggtcgacc ttgccggtga gtccgagcgc
    19321 cagcagcgtg cggccgtgga aggcgccgtt gaaggcgatc acgcccgggc ggccggtaaa
    19381 ggcgcgcgcg atcttgaccg cgttctcgac cgcctcggcg ccggtgctca ccagcatggt
    19441 cttcttcggg gcgtcccccg gcgcgagcgc gttgaggcgc tcggccaggc gcaggtagcc
    19501 gtcgtaggcc acgacctgga agcaggtgtg gctgaagtgg gtgagctgcg cctgcgccgc
    19561 ggcgaccacg cgcgggtggc agtgcccggt gttgaccacg gcgatgccgg cgacgaagtc
    19621 gatgaaccgg cggccctcga cgtcccagac ctcggcgttg agcgccttgg tggcgaacag
    19681 cgggtgggcc tggccgacgc cgcgcggcag cgcggcggca cggcgggcca tgaagtcggc
    19741 gttgtgcagg ccggggggga tggtgttggc gttcatgggt ttctcctgtc gattcggttg
    19801 gggtggcggc ggctcactgc acgccgccca tgcacagata cttgacctcg aggtagtcct
    19861 cgatgccgta cttggagcct tcgcggccga ggccggagga cttcatgccg ccgaagggcg
    19921 cgacctcggt cgagatgatc ccggtgttga tgccgacgat gccgtactcc agcgcctcgc
    19981 cgacccgcca cacgcggttc atagagctgg cgtagaagta cgccgccagg ccgaactcgg
    20041 tgtcgttggc catgcggatc gcctcggcct cgtccttgaa gcggaacagc ggcgccaccg
    20101 ggccgaaggt ctcctcgcgc gccaccttca tcgccggggt cacgtcgacc aggatggtgg
    20161 gctcgaagaa gctgccgccg agcgcgtggc gcttgccgcc ggcgagcacg cgcgcgccct
    20221 tctccaccgc gtcggcgatg tgctcctcga ccttggccac cgcgttcatg tcgatcagcg
    20281 ggccctgggt gctgccctcg gcgaggccgt tgcccacctt caggcgcgcc accgcggcgg
    20341 cgagcttggc ggcgaaggcg tcgtacacgc cgtcctgcac cagcaggcgg ttggcgcaca
    20401 cgcaggtctg cccggtgttg cggtacttgg aggcgagcgc gccctcgacc gcggcgtcga
    20461 ggtcggcgtc gtcgaagacg atgaaggggg cgttgccgcc gagctcgagc gagagcttct
    20521 tgatgctggg cgcgcactgc gacatcagct tgacgccgat ctcggtggag ccggtgaagg
    20581 tgagcttgcg cacgatcggg ttggcggtca gctcgccgcc gatctcggcc gcgccgccgg
    20641 tgaccacgct gaacacgccc ttgggaatcc ccgcgcgctc ggcgagcacc gccagcgcca
    20701 acgccgagta cggcgtctgc gtggcgggct tcaagaccat cgtgcacccg gccgcgagcg
    20761 cggggccggc cttgcgcgtg atcatcgccg ccgggaagtt ccacggcgtg atcgccgcgc
    20821 acacgccgat cggctccttg gtgacgacga tgcgcttgtc gggctggtgg ccggggatca
    20881 cgtcgccgta gatgcgcttg ccttcctcgg cgaaccactc gatgaaggag gcggcgtaga
    20941 gcacctcgcc gcgcgcctcg gcgagcggct tgccctgctc gctggtcatc agcacggcga
    21001 ggtcttcctg gttggcgagg atgagctcga accagcgccg caggatcttc gcgcgcgcgc
    21061 cggcggtcag cgcgcgccac gccggccacg ccgtgttggc ggcctcgatg gcgcgccggg
    21121 tctcggccgc gcccatgcgc gggatggtgc cgagcgcctc gcccgtggcg gggttgcgga
    21181 tgctcagggt ggcgccgtcg tcggcgtcga tccactgccc gtcgacgtag cagcgggtgc
    21241 ggaagaggtc gggatctttc aggttcaggc tcatggtcgg tgtccgtcgg gtggtcgggg
    21301 aaagcttcgg tgtgtgctcg gggcgtgccg ggcttggcgt ggtcgggtcg ctcagcggcg
    21361 cgcgccgcgc atacgctcgg cacgccggcg cagccattcg agggtcatca gcatcagcgt
    21421 cgacagcacg atgaggatgg tcgcgaccgc ggcgatggtc gggctgatgt tctcgcggat
    21481 gccggcgaac atctgccgcg gcagcgtcgc ctgctcgggg ctggcgagga agagcgtcac
    21541 cacgacctcg tcgaaggagg ttgcgaaggc gaacaggccg cccgagatga tcccgggcgc
    21601 gaccatcggc agggtgacgc ggaagaaggt ggtgaccggg ttggcgccga ggctggaggc
    21661 cgcgcgcacc aggttgaagt cgaagccctg cagcgtcgcg gtcaccgtgg tgacgacgaa
    21721 gggcacgccg aggatggcat gcgccagcac caggccggtg tagctgccgg tgaggccgag
    21781 cggggcgaag aagatgtaca tcgccacgcc gatcaccacc accggcacca ccatcggcga
    21841 gatcagcacg gcggtgagca gggccttgcc ggggaagtcg gcacgcacca ggccgatcga
    21901 ggccagggtg ccgagcacca tcgccagcag ggtggcgagc ggcgacacga tcaggctgtt
    21961 catcagcgcc tgccgccagg ccggcgaggt ggcgaactcc tcgtaccagc gcagcgagaa
    22021 gcccgacatc gggtacatca ggaagctgtc ggcgttgaag gacagcggca cgatgaccaa
    22081 gatgggcagg aacaggaagg ccaggatcag tccgaccagc ccgcgcatgc cgaaatacca
    22141 tgcccgttcc acgggcgaag cgtagggttg cagcatcgtc gtcgtcctca gcgtgccttc
    22201 atgtacttga cccgggtcgg cccgaggtag cgggcataga ccatgtacag cagcagggtc
    22261 gccgccagca gcaccgcgga gagcgcggcc gccatgcccc agttgatcgt ctggttggtg
    22321 tagaaggcga tgaagtagct cagcatctgc tccttcgggc cgccgagcag cgcgggcgtg
    22381 atgtagtagc ccatgcacat gatgaacacc agcaggccgc cggcgccgat gccgggcagg
    22441 gtctgcggga agtagatctt ccagaagctg cggaagggcg ggcagccgag cgagagcgcg
    22501 gcgcgcatgt ataccggcga gatgcccttc atcaccgagt acagcggcag caccatgaag
    22561 ggcagcagga tgtggaccat cgccacatac acgccgaagc ggttgaacag gagctggagc
    22621 gggctgtcgg tgaggccgag ccacatcagc aggcggttca ccaggccctc gttctgcagc
    22681 agcacgatcc acgccgccac gcgcaccagc accgaggtcc agaacggcag cagcacgaag
    22741 atcatcagca tgttgctgtg gcgggtggac aggctggcca tcaggtaggc caccgggaag
    22801 ccgagcgcca ggcagcacac cgtgacaatc aggctcatcc agaaggtgcg cagcagcacg
    22861 tccacataga tgcgctcgtc ctcgggggcg gcgacgatgt cgccgtcggc gtcgatggcg
    22921 cggtcgatcg cggcgagcag gtagaagggc gtcagcgcgc cgccggcgcg gtggatcgcc
    22981 tgccaggtgg cgagctcgcc ccactgcgca tcgatcgcca ccagcgcctc gcgcgccggc
    23041 acggcggcgt cgagcggcag cttgcgcgcg gtcttcatga ccaggctgcg atagccggcg
    23101 ttctcgcggt tcaggcgctt ggcgatcgcg gcgatcgccg gcgagccctt ggccgctgcg
    23161 agctcgtcgg cgagcgcgcg gaaggcggcc tcgtccggcg gcgcgctgcc gttccagtcc
    23221 tcgagcacgg cgagcgtgcg cggcaggttg tcgtggatct cggggttatc gacgccgatc
    23281 gtcagcagcg agccgatcgg ccagatgaag gccaccagca ccaccagcgc gagcggcagg
    23341 atcagggcgc cgaagagcag gttgcggcga cgctcggcgc ggcgcaggcg cttcttcagc
    23401 ggcgtgccgt cgccctcggc gggcaagggt acggcagcgg aggtgtcgac ggcagtgctc
    23461 atggacttgt ccactcggtc agatggagac ggtggccgcg cgtcgcggcc gccaccgcgg
    23521 gccggacgcc cgcggcggcg caggcatgcc cgcgcgcggg catgcgacga aggcagcgct
    23581 cagcgcgcgg cccaggcgtt gaagcgctgc tcgaggttct cgccgtgctc gacccagaac
    23641 tcggtgtcgg tcgccatcgc gcccgtcatg ttctcgggcg aggtcggcaa gccggcggcg
    23701 accttggcgt cgatggccgg gaccgccttg aggttgaccg ggccgtaggc gatctcgccg
    23761 gagaacaccg cctggttgtc cggctggctg gcgaagcgga tgaacttgag cgcgtcggcc
    23821 ttgttcggcg agcccttggg aatggcccac gaatcgacgt cgtagatgct gccgttccag
    23881 accaccttga ggttcttgcc ttcgacctgc gcagcggaga tgcggccgtt gtaggcggcg
    23941 ctcatgacca ggtcgcccga ggcgagcagc tgcggcggct gcgcgccggc ttcccaccac
    24001 tggatgttcg ccttgagctt gtcgagcttg gcgaaggcgc ggtcgacacc ggccggggtg
    24061 gcgagcacct tgtatacatc gctggtcggc acgccatcgg cgagcagggc gaattcgagg
    24121 gtgtacttcg cgcccttgcg caggccgcgc ttgccgggga atttgtccac gttccagaag
    24181 tcggcccagg aggtcggcgc ctccttgagg cggtcggcgt tgtaggccag cgcggtcgac
    24241 cacacgaaga tgccgacgcc gcattcgttt accgccgccg gcacgaagtc cgccttgtcg
    24301 cccacctgcg cgaagtcgat cttctcgaac aggccttcct cgcagccgcg caccagctcg
    24361 ggcgactcga cctcgagcac gtcccaggtc acgttgccgg cctcgaccat ggccttcacc
    24421 ttggcctgct cgccgttgta ctcgccggcg acgaccttga caccggtggc cttggcaaag
    24481 ggcgcgtagt aggccttgtc ctgcgccttc tgcgaggcgc cgccgaagga gatgacggtg
    24541 atgtcggccg atgcggtgcc gacggcaccg ccgagggcga cgaggacggc ggcgcgaagg
    24601 aaggatgcgg cgtgcttcat gatgtgtctc cggttctggt tatgtaggtg ctgcaggtga
    24661 aggccggcgg ccggccggaa ctgcggatgc ctcggtgggc ggatgcctca gtgcgccgcg
    24721 ggcacgtcga gcgcccgcgt gtgcgccgga tccagcccga cgcggatcgc gtcgccgggg
    24781 cgcagcgaac ggtcgagctg cgagatcggc gccttgatgg tgaattcgtg cttgccggcg
    24841 agttcgacgc gcaggcggat ctggtcgccg aggtagatga gctcgcgcac ggtggcgtcg
    24901 agccggttgg cgccctcgcc ctcgccggcg agctgtacgc gctccggacg caccgcgatg
    24961 cgggcgcggc cgccggcacc gacgttgccg gtgcgcgcgc gcagcaccgt gccgcagtcg
    25021 aggcgcacgt cgcactcctc gcccgccacg gccaccacgg tgccgtcgag cgcgttgttc
    25081 tcgccgatga agtcggcgac gaaggagttc gtcgggtatt cgtacagcgc ctcgggggca
    25141 tcgatctgct ggatcacgcc gtggttgaac acggcgatgc ggtccgacat ggtcagcgcc
    25201 tcgctctggt cgtgggtgac gaacaccacg gtgatgccga ggttctgctg gatgtgcttg
    25261 atctcgagct gcatgcgctc gcgcaggttc ttgtcgagcg caccgagcgg ctcgtccatc
    25321 agcaccagct gcggatcgaa cacgagtgcg cgggcgagtg cgatgcgctg ctgctggccg
    25381 cccgagagct gctgcggata gcggttgccg aaggcctcga gctgcaccat gccgagcgcg
    25441 cgcttcaccc gcgcctcgac ctcgttggcc gccagcttgc gcacacgcag cggaaagcgc
    25501 aggttgtcgg ccaccgtcat gtgcggaaac agcgcatagt tctggaacac catgccgatg
    25561 ttgcgacggt agggcggcac ccggttgatg acctcgccgt caaggcggat ctcgccgccg
    25621 gtgggcgtct cgaagccggc cagcatcatc aggcaggtgg tcttgcccga gcccgacggc
    25681 ccgagcaggg tgaggaactc gccgcggcga atgtcgagat tgaggtcccg cacgatcagg
    25741 gtttcgccgt cgtaggtctt ctggacgttg cgaaagctga cgtggggtgc ctggctgttg
    25801 tggaccgctt ccatctgtct ccgtctcctg caagtggcgc tgtgcgctct ggcgatcgaa
    25861 tcctaggtca cgaattggcc caggcttgat ccaattactt atactttgat agaaccaatt
    25921 tttgctgcac cgcaatggat tgccgactca gctgcgagct catcgtccac gcctacgcgg
    25981 agcaggcgcc ctcttccagc gcccgcgcgc gtctctatct cgccatccgc gaggccatca
    26041 tcgcgcgccg cctcgccccc ggcactgcgc tgccgcccac ccgtaccctg gcggcagagc
    26101 tcgcgttggg gaggaacacc gtggtgcggg tatacgacca gctcatcgtc gagggttacc
    26161 tggacagccg cgtgggctcg ggcaccttcg tctccgacgc ggtggctgct actgcaccgc
    26221 agcaaaaacc acggcggatg gtcggcgcgc gcagcgaggg attgtcgaaa agagggtgcc
    26281 ggatcgccgc agacgcgctg tcgagccggg tgcaggcggg cgccttcatg cccggcttcc
    26341 cggacgtcac ccacttcccc ttcgccacct ggcgcaagct ggtcgccaag cagatgcggc
    26401 tcgagcagcg tcacctggcg cagtacggct acggcggcta cgggccactg aagctggtgc
    26461 tcgccgaata cctgcgcgtg acccgcatga tgtcgtgcag cccgcagcag atcctgatcc
    26521 tgaacggctc gcaccaggcg ctcgacctgt gcgcgcgcat gctcgccgac gtcggcgacg
    26581 tggcgtggat ggaggatccg ggctactggg gggcgcgcaa cgtgctgtcc gcctgcgatc
    26641 tggccatcca cccggtgccg gtggacggcc agggcatcaa cccgcaggaa gccgactggg
    26701 accatcctcc gcggctgatc ttcgtatcgc cgtcgagcca gtacccgacc ggggcggtga
    26761 tgtcgctgga acggcggctg cgcctgctcg aatacgccga gaagaaccgc atctggatca
    26821 tcgaggacga ctacgacaac gagatccgct accacgacca cccggtggcc tcgctgttcg
    26881 gcctgtcggc cgcgcaacgg gtgatctacg tcggcacctt cagcaaggtc atgtaccccg
    26941 gcctgcgcct ggcctacctg gtggtgccgg aggatctcgt cgaggccttc accaccggca
    27001 acgccgagct ctaccgcgag ggccgcatgc tcgagcaggc ggcgctggcc gagttcatcg
    27061 acggcggcca tttcaccacc cacatccgcc gcatgcgcgg catctacgag gagcgccgcg
    27121 accgcctcat cgaggtgctg cagcgccacc tcgccggcat cgccacgcca gccggcggcc
    27181 tcgccggcct gcacatcccg gtccacttcg agtgcccgct cgacgacgtg ctgctggcca
    27241 cccaggcatt acgcgaaggc gtggtgatgc ggccactatc gctctacgcg atcgacgcca
    27301 ccaaccggcg cccgggcatg aatctcggct tcgccgcggt gcccgtcgag cagatcgaag
    27361 cgcccgccct caagctggtg cggctgatcc atggcctgct gccggcagga agccgctgag
    27421 cgcgggcaaa aaaagcggcc gccggtcgca tcggaccgga cgagccgcga gggggagagg
    27481 cgggtaggag tcaggccgcc gcgacgagcg cggggactgc ctcgaaaagg tcggccacga
    27541 ggccgtagtc ggccacctgg aagatcggcg cttcgggatc cttgttgat
//
LOCUS       DAOTIN010000038        27481 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_1996_length_27481_cov_8.866951, whole genome shotgun sequence.
ACCESSION   DAOTIN010000038 DAOTIN010000000
VERSION     DAOTIN010000038.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 27481)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 27481)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27481
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1996_length_27481_cov_8.866951"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1598)
                     /locus_tag="P5537_07835"
     CDS             complement(<1..1598)
                     /locus_tag="P5537_07835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HRV77993.1"
                     /translation="MQQALARHHSIFLLILRRMRAPLILLIVLFAIAVLGLTLVPGPV
                     IDGKTSYLSFFHAFYFISYTATTIGFGEIPYTFSDQQRLWVIVSIYLSVIGWAYTLGS
                     VFNLLADRSLRQAVSMQGFVRSVRRLREPFYLVCGYGETGRLICDALDRMGLRVVVIE
                     VDENKLGELDLHSYSADVAALCADAANPETLAFAGLTHPSCIGVIALTNDDATNLAIA
                     IAARLLAPRLPALCRAERTATSANMASFGTRHILNPFERFSETLALSLHAPKASQLFD
                     WLTGLPGSDVEQRRDPPRGNWIVCGHGRFGRLLVDAMDSEAVPVTIIDIDPKPDGIHR
                     WVQGDGTGAASLLEAGVCEATGIVCGTSSDVDNLSIAVTARELNKELFVILRQNHESN
                     RALFEAFESDITVVPSRVIAHECIAILSTPLLAPFLDEIRRRDEEWCGALLNSLTHRL
                     GWRVPEIRSQRVNLSRAPALYRRLMRGETITLERLLRSPADRSIALDCEVLYLDRDDD
                     DHVMTPAPDEKIRPGDELLFAGTRR"
     gene            complement(1624..2007)
                     /locus_tag="P5537_07840"
     CDS             complement(1624..2007)
                     /locus_tag="P5537_07840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6394 family protein"
                     /protein_id="HRV77994.1"
                     /translation="MNLEKVIFGFFIVLAATLNFGFFVGDIENPAHHDVYELFAALVV
                     SLIATVLKFGDRTQIGAVHLSTSLVADLQLIAAAMVWGYAAHLSEGGLSPEMTARVVS
                     LSGGALFANVVSVIILIAETIMQRR"
     gene            complement(2098..2490)
                     /locus_tag="P5537_07845"
     CDS             complement(2098..2490)
                     /locus_tag="P5537_07845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011238790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YchJ family metal-binding protein"
                     /protein_id="HRV77995.1"
                     /translation="MKKPATPCPCGSGRAFGACCGPALSGERPAPTAEALMRSRYTAF
                     TLHDTAYLLASWHPSTRPQDLALDEQPQPKWIGLEVRAHRPLADDRAEVEFLARCRIG
                     GRAQRLHETSRFVMEGGNWYYVDGDLHD"
     gene            complement(2668..5367)
                     /gene="acnA"
                     /locus_tag="P5537_07850"
     CDS             complement(2668..5367)
                     /gene="acnA"
                     /locus_tag="P5537_07850"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003994 - aconitate hydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase AcnA"
                     /protein_id="HRV77996.1"
                     /translation="MSATPFDTLRPLPSSDGRLSYHSLPALEEAGVGRISRLPVSIRI
                     VLEAVLRHCDGDKVTAEHVRELASWQPEAERSAEIPFVVARVVLQDFTGVPLLADLAA
                     MRSVAVAQGREAKLIEPLVPVDLVIDHSVQVDHYGTPDALRRNMEIEFERNRERYQFM
                     KWGMQAFDTFRVVPPGIGIVHQVNLEYLFRGVRARDGLCFPDTLVGTDSHTTMINGVG
                     VVGWGVGGIEAEAAMLGQPVYFLTPDVVGVELRGRLPAGTTATDLVLAVTEMLRREKV
                     VGKFVEFFGEGTASLSVTDRATIANMAPEYGATMGFFPVDGKTIEYMRATGREEAECA
                     LMEDYFRAQGLFGVPRAGEIDYTRTLVLDLATIQPSLAGPKRPQDRIALPAMRHAFER
                     LFSAPVSENGFGREPGQLDDRFATAREGVVLGHGDVLIAAITSCTNTSNPAVMLAAGL
                     LAKKAVERGLRVKPHIKTSLAPGSRVVTDYLGKAGLLEPLATLGFALAGYGCTTCIGN
                     AGDLAPEFNEAIAEHDLVVAAVLSGNRNFEARIHPNLRANYLASPPLVVAFALAGRAN
                     IDLTQEPLGTGSDGRPVFLRELWPSSDEIAAAVPFATDPATYRRLYADFTRDHDLWNA
                     IPAPSGQVYDWPPSTYIACPPFFDGFSMTPPPARDLRDARALLLLGDSVTTDHISPAG
                     SFRETSPAGRWLREQGVEKKDFNSYGSRRGNHDVMVRGTFANVRVKNLMLPPNPDGSR
                     VEGGYTLLDGEQTTVYDAANAWMARGVPTMVFAGEEYGTGSSRDWAAKGTALLGVKAV
                     VARSFERIHRSNLVGMGVLPLQFVGEDSWQALGLDGSEQFTLEGIAAGLAPRQQLTLQ
                     IERADGSRRSVPLLCRIDTPIEIEYYRHGGILPYVLRGILGGR"
     gene            6097..8694
                     /gene="acnB"
                     /locus_tag="P5537_07855"
     CDS             6097..8694
                     /gene="acnB"
                     /locus_tag="P5537_07855"
                     /EC_number="4.2.1.3"
                     /EC_number="4.2.1.99"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011765267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003994 - aconitate hydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aconitate hydratase
                     2/2-methylisocitrate dehydratase"
                     /protein_id="HRV77997.1"
                     /translation="MLEAYRAHVAERAALGIPPLPLSKQQAAELVELLKNPPAGEEAF
                     LVELLTYRVPAGVDDAAKVKAEFLAKVAKGEEACGLVSRAKATELLGTMLGGFNIKPM
                     IDLLGDAEVGAVAAEGLKKTLLMFDYFHDVKELAEKGNANAKAVMQSWADAEWFTSRP
                     EVPASQKLTVFKVTGETNTDDLSPAPDAWSRPDIPLHALAMLKNPRPGITPEEAGVRG
                     PVKFLEELRAKGNLVAYVGDVVGTGSSRKSATNSVLWFTGEDIPFVPNKRFGGVCLGS
                     KIAPIFFNTMEDAGALPIEIDAGQMDMGDEIELKVDAQSGKVTALKNGAVIAESQLKT
                     LVILDEVRAGGRIPLIIGRGLTSKAREALGLPPSTLFRLPQAPADTGKGFSLAQKMVG
                     RACGMPEGQGIRPGTYCEPKMTTVGSQDTTGPMTRDELKDLACLGFSADLVMQSFCHT
                     AAYPKLVDVKMHRELPSFISTRGGVALRPGDGVIHSWLNRLLLPDTVGTGGDSHTRFP
                     IGISFPAGSGLVAFAAATGVMPLDMPESVLVRFKGKMQPGVTLRDLVNAIPLYAIRQG
                     LLTVEKKGKKNVFSGRILEIEGLPDLKVEQAFELTDASAERSAAGCTVHLNKEPIVEY
                     MNSNITLMKWMIANGYQDARTLKRRIKAMEDWIANGTLLSGDADAEYAAVIEIDLADI
                     KEPIVACPNDPDDVKLLSEVAGDKIDEVFIGSCMTNIGHFRAAGKVLDGKSDIPTRLW
                     IAPPTKMDAMILNEEGYYGVLGKSGARMEMPGCSLCMGNQAQIRKGSTAMSTSTRNFP
                     NRLGIDTRVYLGSAELAAVCALMGKIPSVAEYMAQVEVVNKKAADIYRYMNFDQIEEF
                     RSVADTVEV"
     gene            8938..9168
                     /locus_tag="P5537_07860"
     CDS             8938..9168
                     /locus_tag="P5537_07860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015452271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system CcdA family
                     antitoxin"
                     /protein_id="HRV77998.1"
                     /translation="MNHDLGIRSMNPARIIDEHSPAYIPISDEQAAETCLAWPVAERR
                     AAQWLEENRAALDSSNAYIEDHGLPLAPFRNF"
     gene            9223..12357
                     /locus_tag="P5537_07865"
     CDS             9223..12357
                     /locus_tag="P5537_07865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3427 domain-containing protein"
                     /protein_id="HRV77999.1"
                     /translation="MTLPDGLYDQLLTDALRDDVMRTTDEHAHSLQPLAVEDAPERLA
                     DALAAQLARILDDLHGDGAEKLRQQLDLVNFLLVSLKQRLGKRADDAEPLSAPPQILQ
                     AIHQRSPKPAIPETGLAFPWLFTAGKGSPSLLTELRRELAACDQVDILVSFITHSGVR
                     KLLDILQSITAVGPDGEPRARLRVLTTTYTGATEIRALDELARLPGCDIRVSLDGRRT
                     RLHAKAWLFRRRTGFGSAYVGSANLSGAALMGGLEWTVKFTERGQRDLFERASAHFET
                     LWEDSEFQAYDPANPAHRKALGEALRRESGDELNARPTYFDLEPKAYQQEMLDQLQIE
                     RDHGRWRNLVVAATGTGKTVVAAFDYKRLCQQTGGRPRLLFVAHREEILKQALRTYRE
                     VLRDHAFGEVLVGGVQPEGFEHLFATIDSVSVRELVSRCGADHWHTVVVDECHRLAAD
                     RFDAFVSAVRPRVLLGLTATPERSDGKPILGYFDNRPDGSPAVELRLWHALDQQLLCP
                     FEYYACDDETDFSAVPWQQAGEVAAIDRLVTGNDVRARLVLDEWRRLTGDPARGRTLV
                     FCVSVAHAQDMTARLNKAGIRALCVVGDTPTDERRRAPEMLARGEVAALVTCDLFNEG
                     VDLPLVDTLLLLRPTQSPVLFQQQIGRGLRLAKGKESCLILDFVGRHREEFRFDRLLS
                     KLTGLSRAQLIEAVDKGFGLLPPGCHIHLQRQTREQVLRSLRKLVQQNWRRLRTELQA
                     YAALRGRTDIRLASFLAEQAIELDDLYRSSGRSGWTNLKRDAGLLSGPAGSEDDYFGR
                     RFGDLLHIDDPARTDLLCSLREPDAAYRARDERERRLLQMLAYQIDAQQHQKVSGEDF
                     LQRLQHHPEHTAELAELGGVLQARSSLRAQPVPGLEDVPLCLHAAYGIREILTALGWL
                     SPSRRTPFQAGVLALHERKVELLFVTLDKCEGYHERIAYRDYAISPELFHWQSQNAAG
                     PQTPAGRRYLESPGNGWTFQLFVRAAKGTPYRACGPVTLERAEGAKPMSIHWRLGVPL
                     PGRLFREFSILRGA"
     gene            12444..13271
                     /locus_tag="P5537_07870"
     CDS             12444..13271
                     /locus_tag="P5537_07870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HRV78000.1"
                     /translation="MNPRRLPSRIVCLTTETVEVLYALGEQDRIAGISGYTVIPPRAR
                     KEKPKVFAFSSGDLEKILAVAPDLVLGFSDMQADVARDLIKAGVAVHVFNQRSVAGIL
                     AMIETVGRLVGAEGRALALVAELEATMDAVRARAAALPRRPRVYFEEWDEPPISAVGW
                     VSELVAIAGGEDVFAERACHPGAAQRILADPLEAARAKPDIVVGSWCGKRFRPERVAE
                     RPGWEAVPAVRDGELHEVKSALILAPGPVAIREGLPALAEIIARWARRAFDGYSAAR"
     gene            13396..13668
                     /locus_tag="P5537_07875"
     CDS             13396..13668
                     /locus_tag="P5537_07875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016535194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HRV78001.1"
                     /translation="MNKQELVASIAEKAGMTKADAARALDATVAAVTEALRQDETVTL
                     VGFGSFYVGERAARTGRNPRTGKNIKIKAAKVPKFRAGKGLKDSVN"
     gene            13708..13783
                     /locus_tag="P5537_07880"
     tRNA            13708..13783
                     /locus_tag="P5537_07880"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13741..13743,aa:Val,seq:tac)
     gene            14137..15243
                     /locus_tag="P5537_07885"
     CDS             14137..15243
                     /locus_tag="P5537_07885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPP family protein"
                     /protein_id="HRV78002.1"
                     /translation="MSLSRLFSLPAALSAGRREMALGTLGVAVGLGCTEWIGYLALGG
                     QVPWFIIPMGASAVLLFCLPASPLAQPWPSLAGNLVSALVGVGCYRWLGETGAAVALA
                     GCLAVGVMFVLRCLHPPGGAVALTAVLGGPLVHELGYGFALMPVLANTLAMLVVAFLF
                     NNLVGRRYPHLAPTRPQPHDTADPLPSKRVGFRAEDLDAALASFGEVLDVDRDDLEEI
                     MVRAQMNARRRTWGALRCADIMSRDVVSAGPQAPVAEAWALLAHHRIKALPVVEEGGR
                     LVGIVSVPDFFIDRHNPEPQPVPRMSTARVVAEIMSARVRSARPGQSLADLVGAFSDG
                     GMHHLPVTDEDGRLVGMITQSDVVAALFAGERAA"
     gene            15320..15670
                     /locus_tag="P5537_07890"
     CDS             15320..15670
                     /locus_tag="P5537_07890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HRV78003.1"
                     /translation="MTDRSNAARTEIRVEKLKEMLDFQQQAIVSRMLLKNAAGSVTLF
                     AFDEGEGLSEHTAPFDALLIGVEGEAEVRVDADLHRLGEGATLLIPAGAPHAVAPCAQ
                     FKMLLVMLKGERKA"
     gene            15762..15974
                     /locus_tag="P5537_07895"
     CDS             15762..15974
                     /locus_tag="P5537_07895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3079 domain-containing protein"
                     /protein_id="HRV78004.1"
                     /translation="MAKKFPLHPKNPERICWGCDKYCSVDALGCGNGSGRTQHPIELL
                     GDDWYTYGDWGIDPEDPATPGRKKAE"
     gene            16263..16811
                     /locus_tag="P5537_07900"
     CDS             16263..16811
                     /locus_tag="P5537_07900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phasin family protein"
                     /protein_id="HRV78005.1"
                     /translation="MTKIQTPEQFAAVGQANLEAMMSLANSAIARAERLAELNLNTVR
                     SVLEDSVATTRKLAEAKDPQQLAKLQGELTKPMLDKAVAYARSVQEIATEGQQEVSNL
                     FEKQIADLNKRFHEMLEQAAKQAPAGSEGVFEAVRSAMNTANSLYDNASKAARQAAEV
                     AEANMAAATEATVKAVSAATKK"
     gene            17060..17134
                     /locus_tag="P5537_07905"
     tRNA            17060..17134
                     /locus_tag="P5537_07905"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17092..17094,aa:Val,seq:cac)
     gene            17199..17273
                     /locus_tag="P5537_07910"
     tRNA            17199..17273
                     /locus_tag="P5537_07910"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17231..17233,aa:Val,seq:cac)
     gene            17417..19264
                     /locus_tag="P5537_07915"
     CDS             17417..19264
                     /locus_tag="P5537_07915"
                     /inference="COORDINATES: protein motif:HMM:NF036516.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M61 family metallopeptidase"
                     /protein_id="HRV78006.1"
                     /translation="MSARSIRSSAAAPSSHDRRLPAVEYRIRPANPGAHLFEVSCTVA
                     EPDPAGQVFSLPAWIPGSYMIREFARNIVRIRAEADGAPCALEKLDKHTWRAAPVRGA
                     RSLSVHYEVYAWDLSVRTAHLDTTHGFFNGTSVFLAVAGRSDAPCVVTIERPEGESGR
                     DWKLVTALPPEHGRPGQACRFGRFRAADYDELIDHPVEMGRFTLARFEAAGVPHDIAL
                     TGRHDCDLERLCADLRRVCEWQIALFGAPAPVDYYAFLTMVVGEGYGGLEHRASTALI
                     CSRAELPWKGMEGLPDGYKSFLGLCSHEYFHTWNVKRIKPAAFTPYELARENHTRLLW
                     AFEGFTSYYDDLALVRSGVIGIDDYLGLLGKNIANVLRGSGRLKQSVAESSFDAWTKY
                     YRQDENAPNAIVSYYAKGALIGLALDLQLRAGSEGAASLDDVMRLLWQRHGLTGIGVP
                     EDGIFAAVREVGGERLGVRLAKWLQKAVEGCEDLPLARLLRPFGVTLRADAAGSAPVL
                     GMKLAAGGGEAKVASVYDDGPAQAAGISAGDVLIALDGLRIANAKAVDELLARRRAGD
                     EVELHLFRRDELMSFRAVLAAPPAERQELKLAPRADSEALRLRRGWLGG"
     gene            complement(19367..19957)
                     /locus_tag="P5537_07920"
     CDS             complement(19367..19957)
                     /locus_tag="P5537_07920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78007.1"
                     /translation="MPDTSPTVAVSAPSNRSSTPPPGDRDRRRALFALLVCVVALPAS
                     WLLFSQLERLWPEIVRLEGIPFLAAATLLGGAMAIGPLAAALGFLVAVWFGVRSVYSP
                     RSRTTPLLDRVIVGAGLLVWFMPALAAIAQAVRALITGRIHFVRPPRDYFLATDPIAF
                     WQGVGFWLIIAALAGFLAWRYWQPKLFPAATATPAA"
     gene            complement(20056..21636)
                     /locus_tag="P5537_07925"
     CDS             complement(20056..21636)
                     /locus_tag="P5537_07925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase Y family protein"
                     /protein_id="HRV78008.1"
                     /translation="MLWLAILLPALPLQVFTRGVREAPPLAILSPRGRVLAASAAASA
                     AGIEAGQRAASALALLPELRLQPREPAREAEALAEIATWAGRFSPRISLSAPDAVLLE
                     ISSCLRLFGGVTQIEAAVREGLGGLGFAARLGCAPTALAARWMARTGAPAEGAAPSRP
                     IPPSFPSAPTAPSNAPIHTPCSTDATHADARDWRAALDPLPIELLSEEDACDAATLEL
                     LAGLGLRTLGELRCLPPAGLARRGAQAAVRTIARARGELADPRPWFEAPLRFHHKLAL
                     PAPELHAEALLFAARRLFASLAAWLDARHAAIDRFCLRFGHGSRAPTEIEFALGRPSR
                     DEARFALIVRERLAVLELSAEVDSITLSAERPLPADPRGTDLFGDPAQAGDDAALLLA
                     RLQARLGENGVQRLDLRADHRPEAAWRNARPSAPAVPPRARRDAPPGAPSTRTPPPPA
                     STAARLRPLWLLPAPHPIAAPRYTLLGAAERIETGWWDGMPVRRDYYLARDADNVLCW
                     IFESLDAPGQWFVHGYFG"
     assembly_gap    21773..21872
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(21924..22793)
                     /gene="imuA"
                     /locus_tag="P5537_07930"
     CDS             complement(21924..22793)
                     /gene="imuA"
                     /locus_tag="P5537_07930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0051782 - negative regulation of cell
                     division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translesion DNA synthesis-associated protein
                     ImuA"
                     /protein_id="HRV78009.1"
                     /translation="MALPLQRHADASLHAAVPVATGTHDVLAGLPAGSVWQASRLAQA
                     GGAVLPTGFAALDAELPGGGWPAGALIELLADRPGVGELSLLLPLLGATPSARWIVCI
                     APPLLPYAPALASAGVPLSRLLVVRPERREDLLWAARQALLSGSCACVLAWPQRIDNA
                     ALRRLQLAAEESATPLFLFRHASVAAQPSPAVLRIALAPHPEGLQLRILKRRGPLSTA
                     ALVLALSPGIGSDSRLPPLLHQSRSRAGSGRSAGRRELRPSGSRSTSTESGTPLFAAS
                     AAPTPEPEPRRFR"
     gene            complement(22816..23424)
                     /gene="lexA"
                     /locus_tag="P5537_07935"
     CDS             complement(22816..23424)
                     /gene="lexA"
                     /locus_tag="P5537_07935"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004320360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HRV78010.1"
                     /translation="MTARSENLTARQQEILDFIRSTVESEGRPPTRAEVCTAFGFRSP
                     NAAETHLRALAAKGAILLEEGRARGIRLAEALGLPLVGRVAAGSPILAAEHVEARYQL
                     DPALFSPRADYLLRVRGMSMRDAGILDGDLIAVHRNGEARNGQIVVARVDDDVTVKTL
                     QRKGAVVELLPANPDYAPIVVDTRREPLVIEGVMVGLIRKDH"
     gene            complement(23494..24531)
                     /locus_tag="P5537_07940"
     CDS             complement(23494..24531)
                     /locus_tag="P5537_07940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HRV78011.1"
                     /translation="MPRPHPNAPASLPSTMRAMQLERPGEALRAVRLAVPRPARGQVL
                     LRVEACGVCRTDLHLIDGELPDPVLPMIPGHEIIGCVVELGEGVGDDAGMAPGQRIGV
                     PWLGWTCGHCGFCASHRENLCDHARFTGYQIQGGYAEYTVADARYCFPIDEALDAAEA
                     APLLCAGLIGYRALEMAGDARSIGLYGFGAAAHIIAQVAVWQGREVYAFTRPGDNESQ
                     AFARQLGACWTGAGDELPPHPLDAALIFAPAGELVPAALRAVAKGGTVVCAGIHMSTI
                     PAFPYDILWGERRIVSVANLTRRDGDEFLALAPKVPVRTEVTRFPLEEANEALLRLRR
                     GALQGAAVLLP"
     gene            24753..25250
                     /locus_tag="P5537_07945"
     CDS             24753..25250
                     /locus_tag="P5537_07945"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HRV78012.1"
                     /translation="MLQSGDIAPAFSLPDADMEIFDLASAAGKHNVVLYFYPRDKTPG
                     CTRQAADFSDHEDEFARHDCIVVGVSPDDCLTHAEFRDQEGLSIRLLSDSDTEVCRLY
                     NVWQEREVDGMKKMGVRRSTFVIDKQGRIRHALYDVTPRGHAAAVFELVKELEPRNAK
                     RNRQE"
     gene            25225..25713
                     /locus_tag="P5537_07950"
     CDS             25225..25713
                     /locus_tag="P5537_07950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HRV78013.1"
                     /translation="MQNEIVKNSVVTLKYTVRDPEGAMIDDGEHPLVYLHGGYDGIFP
                     LLEEALHGKKVGEQLQVKLQPEDAFGDYDEELILVEDAKLFPDNIEIGMSFERVSEDG
                     EEDMIYRITDIADGKVVVDGNHPLAGVALVFDVTVAEVRPASAEEISHGHVHGPGGHH
                     HH"
     gene            25855..>27481
                     /locus_tag="P5537_07955"
     CDS             25855..>27481
                     /locus_tag="P5537_07955"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004320371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015833 - peptide transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HRV78014.1"
                     /translation="MNAPLPADLPEAATAALLHVEGLGVAIARTDGEEVRPVDGVDFA
                     IAAGETFALLGESGCGKSMTALALARLLPDGGRIAAGSVRLGGEDLLALPEAAMRRVR
                     GGRIGMIFQEPSTSLNPVMSVGAQIAEALAAHGLRGEAARVEACRLLAAVGIPDPERR
                     LQEFPFQFSGGMKQRVMIAIALAGRPRLLIADEPTTALDVTIQAQVLDLLAALQRREG
                     MAMLLITHDLGVVARVAHRVGVMYAGQVVETGPRAAFFATPLHPYSRKLFAALPEAAK
                     RGGVLDAPVGSVPPPDRHFPGCRFAERCPAAFDRCDEEAPAWHAVGMQAVRCHLYEGV
                     AVPRPLVATLAGAVDTVAARPAQSVLEVAELAVHFPVRKGFLRRTVGHVKAVDGVSLR
                     LQPGRTLALVGESGCGKTTVGKALLRLIEPTAGRLWLDGERYDTLPVQALRPLRRAVQ
                     MVFQDPFASLDPRMRVGEIIEEGLVALGIGADHRARQARVAELLERVGLAAEMRWRYP
                     HEFSGGQRQRIAVARALAVSPRVIVCDEPTSALD"
BASE COUNT         4279 a         9104 c         9941 g         4057 t
ORIGIN      
        1 cgccgggtgc cggcgaagag cagctcgtcg ccggggcgga tcttctcgtc gggggcgggc
       61 gtcatcacat ggtcgtcgtc gtcgcgatcg aggtagagca cctcgcaatc gagcgcgatc
      121 gagcggtcgg caggcgagcg cagcaggcgc tcgagcgtga tcgtctcgcc gcgcatcagc
      181 cgccgataca gcgccggggc gcgcgacagg ttgacgcgct ggctgcggat ctcgggcacc
      241 ctccagccga gccgatgggt caggctgttc agcagcgcgc cgcaccactc ctcgtcgcgg
      301 cggcggatct cgtcgaggaa gggcgcgagc aacggcgtgc tcaggatcgc gatgcactcg
      361 tgcgcgatca cccggctagg caccacggtg atgtccgact cgaaggcttc gaagagggcc
      421 cgattggatt cgtgattctg gcgcaggatc acgaagagct ccttgttgag ctctcgtgcc
      481 gtcaccgcga tggacaggtt gtcgacatcg gagctggtgc cgcacacgat cccggtcgcc
      541 tcgcaaacgc cggcctcgag cagcgacgcg gcgccggtac cgtcgccctg cacccagcgg
      601 tggatgccgt ccggtttggg atcgatgtcg atgatggtga ccggcaccgc ctcggagtcc
      661 atcgcatcca ccagcaggcg gccgaagcgc ccatggccgc acacgatcca gttgccgcgc
      721 ggcgggtcgc ggcgctgctc gacatcgctg ccgggcaggc cggtgagcca gtcgaagagc
      781 tgcgaggcct tgggcgcgtg cagcgagagc gcgagcgtct cgctgaagcg ctcgaagggg
      841 ttgagaatgt ggcgggtgcc gaaggaggcc atgttggccg aggtcgcggt gcgctcggca
      901 cggcatagcg cgggcaggcg cggtgcgagc aggcgggcgg cgatcgcgat cgccaggttg
      961 gtggcgtcgt cgttggtgag cgcgatcacg ccgatgcagc tcgggtgcgt gaggccggcg
     1021 aacgcgagcg tctcggggtt ggctgcgtcg gcgcagagcg cggcgacgtc ggccgagtag
     1081 ctgtgcaggt cgagctcgcc gagcttgttt tcatccacct cgatcactac gacgcgcagc
     1141 cccatgcggt cgagcgcgtc gcagatcagg cggccggtct cgccgtagcc gcacaccagg
     1201 tagaagggct cgcgcagtcg ccgcaccgat cgcacgaagc cctgcatcga gaccgcctgg
     1261 cgcaggctgc ggtcggcgag caggttgaac accgagccga gcgtgtaggc ccagccgatc
     1321 acggacaggt agatgctgac gatcacccac agccgctgct ggtcggagaa ggtgtagggg
     1381 atctcgccga aaccgatcgt ggtcgcggtg tagctgatga agtagaaggc gtggaagaag
     1441 ctgaggtagc tcgtcttgcc gtctatgacc gggccgggca ccagggtgag cccgagcact
     1501 gcgatcgcga acagcacgat cagcaggatc agcggcgcac gcatgcgccg caggatcagc
     1561 aggaagatgc tgtggtggcg ggcgagggcc tgctgcacgg ctcgggcctc ggcgcgatgg
     1621 cgttcagcgg cgctgcatga tggtctcggc gatcaggatg atcaccgaca ccacgttggc
     1681 gaagagcgcg ccgcccgaga gcgagaccac gcgcgcggtc atctcggggc tcaggccgcc
     1741 ctcgctaagg tgggccgcgt agccccacac catcgccgcg gcgatcagct gaaggtcggc
     1801 caccagactg gtggacagat gcaccgcgcc gatctgcgtg cggtcgccga acttgagcac
     1861 ggtggcgatc aggctgacga ccagcgcggc gaagagctcg tagacgtcgt ggtgcgcggg
     1921 gttctcgatg tcgccgacga agaagccgaa gttcagcgtg gccgccagca cgatgaagaa
     1981 gccgaagatg actttctcga ggttcatgat cttccgttgg gtgcgcgcga tgacgatggg
     2041 gcaattatgc gccggccacg gccgcgatgt cgcgcggcgt gggcggtggg gcggatttca
     2101 atcgtggagg tcgccgtcca cgtaatacca gttcccgcct tccatcacga agcggctggt
     2161 ctcgtgcagg cgctgcgcgc gcccgccgat gcggcagcgg gcgagaaact cgacctcggc
     2221 gcggtcgtcg gcgagtgggc ggtgggcgcg cacctcgagg ccgatccatt tgggctgcgg
     2281 ctgctcgtcg agcgcgaggt cctgcgggcg ggtggagggg tgccagctcg cgagcaggta
     2341 ggcggtgtcg tgcagggtaa aggcggtgta gcgcgagcgc atcagtgcct cggcggtggg
     2401 cgccgggcgc tcgcccgaca gcgccgggcc gcagcacgcg ccgaaggcgc ggccggagcc
     2461 gcaggggcag ggagtggcgg gttttttcat ggggcgggag tatagcgagc cggaccgggg
     2521 cgcatgcagg acgggcggta gccgcgaata ggaccgaccg gaaacgggca tggatgggcg
     2581 aggcaggcgc ggtgttcgcg ccctccggtg ctcctgcaga acggcgtgcg tgcaggagcg
     2641 ctggaaggcg cggatgcaac gcggtgctca gcgacctccc aggatcccgc gcagcacata
     2701 gggcaggatg ccgccgtggc ggtagtactc gatctcgatc ggggtgtcga tgcggcacag
     2761 cagcggcacc gaccgccgcg agccgtcggc gcgctcgatc tgtagcgtga gctgttgccg
     2821 tggtgccagg ccggcggcga tgccttccag cgtgaactgc tcgctcccat cgagccccag
     2881 cgcctgccag ctatcctcgc cgacgaactg cagcggcagc acgcccatgc cgaccaggtt
     2941 ggagcggtgg atgcgctcga agcttctcgc caccaccgcc ttgacgccga gcagcgccgt
     3001 gcccttggcg gcccagtcgc gcgacgagcc ggtgccgtat tcctcgccgg cgaagaccat
     3061 ggtcggcacg ccgcgcgcca tccacgcgtt ggccgcgtcg tacaccgtgg tctgctcgcc
     3121 gtcgagcagg gtgtagccgc cttccacacg gctgccgtcg gggttgggtg gcagcatcag
     3181 gtttttcacg cgcacgttgg cgaaggtgcc gcgcaccatc acgtcgtggt tgccgcggcg
     3241 cgaaccgtag gagttgaagt ccttcttctc caccccctgt tcgcgcagcc agcgcccggc
     3301 cgggctggtc tcgcggaagg agccggcggg cgagatgtgg tcggtggtca ccgagtcgcc
     3361 gagcagcagc agggcgcgcg cgtcgcggag gtcgcgcgcc ggcggcggcg tcatgctgaa
     3421 gccgtcgaag aagggcgggc aggcgatgta ggtggagggc ggccagtcgt agacctgccc
     3481 gctgggggcg gggatcgcgt tccacaggtc gtggtcacgg gtgaagtcgg catacagccg
     3541 gcgataggta gccgggtcgg tggcgaaggg gacggcggcg gcgatctcgt ccgagctcgg
     3601 ccagagctcg cgcaggaaca ccggccggcc gtcgctgccg gtgccgagcg gctcttgagt
     3661 caggtcgatg ttggcccgcc cggcgagcgc gaaggccacc accagcggcg gcgaggcgag
     3721 gtagttggcg cgaaggttag ggtggatgcg ggcctcgaag ttgcggttgc ctgacagcac
     3781 cgcggccacc accaggtcgt gctcggcgat cgcctcgttg aactcgggag cgagatcgcc
     3841 cgcattgccg atgcaggtgg tgcaaccgta gccggcgagc gcgaagccga gcgtggcgag
     3901 cggctcgagc aggccggcct tgccgaggta gtcggtgacc acgcgcgagc cgggcgcgag
     3961 cgaggtcttg atgtgcggct tcacgcgcag gccgcgttcc accgccttct tcgccagcag
     4021 gccggcggcg agcatgaccg cagggttgct ggtgttggtg caggaggtga tggcggcgat
     4081 cagtacgtcg ccgtggccga ggaccacgcc ctcgcgcgcg gtggcgaagc ggtcgtcgag
     4141 ctggccgggc tcgcggccga agccgttctc ggacaccggc gctgagaaca ggcgctcgaa
     4201 cgcgtggcgc atggcgggca gggcgatgcg gtcctgcggg cgcttggggc cggcgagcga
     4261 gggctggatg gtggcgaggt ccagcaccag cgtgcgcgtg tagtcgattt cgcccgcgcg
     4321 cggcacgccg aacaggccct gggcgcggaa gtagtcttcc atcagcgcgc actcggcctc
     4381 ttcgcgaccg gtggcgcgca tgtattcgat ggtcttcccg tccaccggga agaagcccat
     4441 cgtggccccg tattcgggcg ccatgttggc gatggtggcg cgatccgtta ccgacaggct
     4501 ggccgtgccc tcgccgaaga actcgacgaa cttgcccacc accttctcgc gccgcagcat
     4561 ctcggtgacg gcgagcacca ggtcggtggc ggtggtgccg gcaggcaggc ggccgcgcaa
     4621 ctccacgccg accacgtcgg gggtgaggaa gtacaccggc tggccgagca tcgccgcctc
     4681 ggcctcgatg ccgcccacgc cccagcccac cacgccgacg ccgttgatca tggtggtgtg
     4741 cgagtcggtg cccaccagcg tatccgggaa gcacaggccg tcgcgggcgc gcacgccgcg
     4801 gaagaggtat tccaggttga cctgatgcac gatgccgatg cccggcggca ccacgcggaa
     4861 ggtgtcgaag gcctgcatgc cccacttcat gaactggtag cgctcgcggt tgcgctcgaa
     4921 ctcgatctcc atgttgcggc gcagtgcgtc gggtgtgccg tagtggtcga cctgcaccga
     4981 gtggtcgatg acgaggtcga ccggcaccag cggctcgatc agcttggcct cgcggccctg
     5041 cgccacggcc acgctgcgca tcgcggcgag gtcggccagc aggggcacgc cggtgaaatc
     5101 ctgcagcacc acgcgcgcga ccacgaaggg gatctcggcg ctgcgctcgg cctcgggctg
     5161 ccagctcgca agctcacgca cgtgctcggc ggtcaccttg tcaccgtcgc agtggcgcag
     5221 taccgcctcg agcacgatgc ggatcgacac cggcaggcgc gagatgcgac ccacgccggc
     5281 ctcctccagc gcgggcagcg agtgatagga gaggcggccg tcggaggagg gcagggggcg
     5341 gagcgtatcg aatggggtgg cggacatcgc gggtctcctg tttgtgttgg ggccaataca
     5401 caggatagcc ggtggacggg gaagttcctg caggagcagc ccgcctgcct ttgtaggagc
     5461 ggcggcagcc gcgaatggag ggcagcgtcg gcaggccccc gagcgtcgcc ttcgcgcctg
     5521 ccggcgctcc tacatgaacc accacgcgtt ctgggcctcc tttaggcgct gcggcagcgg
     5581 cgaatccggc ggtccgtaaa atgacgctcg tcccggaagc caccaccgcg ttcgcgcctg
     5641 ccggcgctcc tgcatgaacc gccacgcgtt ccggacctcc tgtaggaact gcggcagctg
     5701 cgagtccggc ggcgcggaaa atgacgttcg tgccggaagc catcgccgcc ttcgcgcctg
     5761 ccggcgctcc tgcatgaacc tcgcgctcgc cgcccctgca ggagcggcgg cagccgggaa
     5821 tcgggccttg cggcaggtgg cgcgctcggg gggcgaccac cgctttcgca cccgccggcg
     5881 ctcctgcggt aaccacgaaa cgcgggaggt gccgggtgcg cggggatatc ccccgcggcg
     5941 tgacgaaggc gtagaattag ccggctcgaa tggcgggcga cgagcctcgg tgctgcactg
     6001 caccgcaagt cttataaaag acatataatc tcgcccgatc cggtggggcc gacccgtccg
     6061 gagtcccgat caccgccacc tagtgaggaa gtcgccgtgc ttgaagccta ccgtgcccat
     6121 gtcgccgaac gtgccgccct cggcatcccg ccgctgccgc tctccaagca gcaggccgcc
     6181 gaactcgtcg agctgctgaa gaaccctccc gccggcgagg aagccttcct cgtcgagctg
     6241 ctcacctacc gcgtccccgc cggcgtggat gacgccgcca aggtcaaggc cgagttcctg
     6301 gccaaggtcg ccaagggcga ggaagcctgt ggcctggtgt cgcgcgccaa ggccaccgag
     6361 ctgctcggca cgatgctggg cggcttcaac atcaagccga tgatcgacct gctcggcgac
     6421 gccgaagtgg gcgcggtcgc cgccgagggc ctcaagaaga ccctgctgat gttcgactac
     6481 ttccacgacg tcaaggagct ggccgagaag ggcaacgcca acgccaaggc cgtcatgcag
     6541 tcgtgggccg acgccgagtg gttcaccagc cgcccggaag tccccgcctc gcagaagctc
     6601 accgtcttca aggtcaccgg cgagaccaac accgacgacc tctcgcccgc gcccgacgcc
     6661 tggtcgcgcc ccgacatccc gctgcacgcg ctggccatgc tcaagaaccc gcgcccgggc
     6721 atcaccccgg aagaagccgg cgtgcgtggt ccggtcaagt tcctcgaaga gctgcgtgcc
     6781 aagggcaacc tggtcgccta cgtcggtgac gtggtcggca ccggctcctc gcgcaagtcc
     6841 gccaccaact cggtgctgtg gttcaccggc gaggacatcc ccttcgtccc gaacaagcgc
     6901 ttcggcggcg tgtgcctggg ctccaagatc gccccgatct tcttcaacac catggaagac
     6961 gccggcgcgc tgccgatcga gatcgacgcc ggccagatgg acatgggcga cgagatcgag
     7021 ctcaaggtcg acgcccagtc gggcaaggtc accgcgctca agaatggcgc tgtgatcgct
     7081 gaatcgcagc tcaagaccct ggtgatcctc gacgaagtgc gcgccggcgg ccgcatcccg
     7141 ctgatcatcg gccgcggcct cacctccaag gcgcgcgagg ccctcggcct gccgccctcg
     7201 accctgttcc gcctgccgca ggctcccgcc gacaccggca agggcttctc gctggcgcag
     7261 aagatggtcg gccgcgcctg cggcatgccc gaaggccagg gcatccgccc gggtacctac
     7321 tgcgaaccca agatgaccac cgtcggcagc caggacacca ccggcccgat gacccgcgac
     7381 gagctcaagg acctcgcctg cctcggcttc tcggccgacc tggtgatgca gtccttctgc
     7441 cacaccgccg cctacccgaa gctggtagac gtcaagatgc accgcgagct gccgagcttc
     7501 atcagcaccc gcggcggcgt cgcgctgcgt ccgggcgacg gcgtgatcca ctcctggctc
     7561 aaccgcctgc tgctccccga caccgtcggc accggcggcg acagccacac ccgcttcccg
     7621 atcggcatct ccttcccggc cggctccggc ctggtggcct ttgctgcggc caccggcgtg
     7681 atgccgctcg acatgccgga atcggtgctg gtgcgcttca agggcaagat gcagccgggc
     7741 gtcaccctgc gtgatctggt caacgccatc ccgctgtacg caattcgcca gggcctgctg
     7801 accgtcgaga agaagggcaa gaaaaacgtc ttctcgggcc gcatcctcga gatcgaaggc
     7861 ctgccggacc tgaaggtcga acaggccttc gagctcaccg acgcctcggc cgagcgctcc
     7921 gccgccggct gcacggtcca cctcaacaag gaaccgatcg tcgagtacat gaactcgaac
     7981 atcaccctga tgaagtggat gatcgccaac ggctaccagg acgcccgcac cctcaagcgc
     8041 cgcatcaagg ccatggaaga ctggatcgcc aacggcacgc tgctgtcggg cgacgccgac
     8101 gccgagtacg ccgccgtgat cgagatcgac ctcgccgaca tcaaggagcc gatcgtcgcc
     8161 tgcccgaacg accccgacga cgtcaagctg ctgtccgagg tcgccggcga caagatcgac
     8221 gaagtcttca tcggctcgtg catgaccaac atcggccact tccgcgccgc cggcaaggtg
     8281 ctggacggca agtcggacat cccgacccgc ctgtggatcg ctccgcccac caagatggac
     8341 gcgatgatcc tcaacgagga aggctactac ggcgtgctcg gcaagtccgg cgcccgcatg
     8401 gagatgccgg gctgctcgct gtgcatgggc aaccaggcgc agatccgcaa gggcagcacc
     8461 gcgatgtcga cctcgacgcg caacttcccc aaccgcctcg gcatcgacac ccgcgtctat
     8521 ctgggctccg ccgagctggc cgcggtgtgc gcgctgatgg gcaagatccc gtcggtcgcc
     8581 gagtacatgg cgcaggtgga ggtggtgaac aagaaggccg ccgacatcta ccgctacatg
     8641 aacttcgacc agatcgagga attccgctcg gtcgcggata cggtggaagt ttgagtcggt
     8701 agctagctgg aaggctggga cggccgggaa gccgtctcgc ccgagaaccc ctcgtcagcg
     8761 atggcggggg gtttgcttta tgtggggcag atgatcccgg attgctcgag ccacttcatc
     8821 cgaacgggcg agtaaaccgg cgcaatatcc gtgacggcaa ctgtccgtgg tcgtgggctt
     8881 gcccgcgcat cgaccgctcg gaaccgccgc gttcgatgta ctgaggtagc gttctgcatg
     8941 aatcacgatc ttggcatacg ctcgatgaac cccgcccgca tcatcgatga gcactccccg
     9001 gcctacatcc cgatttcgga cgaacaggca gccgagacct gcttggcgtg gcccgtggcg
     9061 gagcgtcgtg cagcgcaatg gctcgaagag aaccgcgccg cgctggacag ctcgaatgca
     9121 tatatcgagg atcatggctt gccgctcgcg ccgtttcgga acttctgatg gcgcgcttcg
     9181 acgtctgccg aaacggcgcg ggcaagggtt ttctgctcga acatgacact gcctgacggc
     9241 ctctacgacc agctcctgac cgacgccctg cgcgacgacg tcatgcgcac gacggacgag
     9301 cacgcccaca gcctccagcc cctcgccgtc gaagatgccc ccgagcgcct cgcggacgcg
     9361 ctcgccgccc aactcgcccg catcctcgac gacctgcacg gcgatggcgc ggagaagctc
     9421 cgccagcaac tcgacctcgt caacttcctc ctggtgagcc ttaagcagcg cctcgggaag
     9481 cgcgcggacg atgccgagcc gctttccgct ccgccacaaa tactccaggc catccaccag
     9541 cgctcgccca agccggccat tccggaaacc ggcctggcct tcccctggct cttcaccgcg
     9601 ggcaagggct cgccctcgct gctgaccgag ctgcgccgcg agttggcggc ctgcgatcag
     9661 gtggacatcc tggtgagctt catcacccat tccggcgtgc gcaagctgct cgacatcctg
     9721 cagtcgatca ccgcggtcgg gccggatggc gagccgcgcg cgcggctgcg ggtgctgacc
     9781 accacttaca ccggtgccac cgagatccgc gcgctggacg aactcgcgcg cctgccgggt
     9841 tgcgacatcc gcgtgtcgct ggacgggcgg cgcacccggt tgcacgccaa ggcctggctg
     9901 ttccgtcgcc gcaccggctt cggttccgcc tacgtgggca gcgccaacct gtcgggcgcg
     9961 gccttgatgg gcgggctgga atggacggtg aagttcaccg agcgcggcca gcgcgatctc
    10021 ttcgagcgtg ccagcgcgca cttcgagacg ctttgggaag acagcgagtt ccaggcctac
    10081 gaccccgcca acccagcaca tcggaaggca ctgggcgagg cgctcagacg cgagtcgggg
    10141 gatgagctga acgcccgccc gacctacttc gacctcgagc ccaaggccta tcagcaggag
    10201 atgctcgacc aactgcagat cgagcgcgat cacggccgct ggcgcaacct ggtggtcgcc
    10261 gccaccggca ccggcaagac ggtggtggcg gccttcgact acaagcggct gtgccagcaa
    10321 acgggtgggc ggccgcggct gctgttcgtg gcgcaccgcg aggagatcct caagcaggcg
    10381 ctgcgcacct atcgcgaggt gctgcgcgac cacgcctttg gcgaggtcct ggtcggcggc
    10441 gtgcagcccg aaggcttcga gcatctgttc gccaccatcg acagcgtgtc cgtgcgcgag
    10501 ttggtgtcgc gctgcggtgc cgatcactgg cacaccgtgg tggtcgacga gtgccatcgc
    10561 ctggcggcgg atcgcttcga tgcattcgtg agcgccgtgc gcccgcgcgt gctgctcggc
    10621 ctgaccgcga cgccggagcg cagcgacggc aagccgatcc tgggctactt cgacaaccgg
    10681 ccggatggct cgccggcggt cgagcttcgg ctctggcacg cgctcgacca gcagctgctg
    10741 tgccccttcg agtattacgc ctgcgacgac gagaccgact tttccgccgt gccgtggcag
    10801 caggcagggg aggtggcggc gatcgacagg ctggtcaccg gcaacgacgt gcgcgcgcgg
    10861 ctggtgctcg acgagtggcg gcggctgacg ggcgacccgg cgcgtgggcg cacgctggtg
    10921 ttctgcgtct cggtggcgca cgcgcaggac atgacggcgc ggctgaacaa ggctggcatc
    10981 agggcgctgt gcgtggtggg tgatacgccc acggacgagc gccggcgtgc gcccgaaatg
    11041 ctggcgcggg gcgaggtcgc cgcgctggtg acctgcgacc tgttcaacga gggcgtcgac
    11101 ctgccgttgg tcgatacgct gctcctgctg cgcccgacgc agagcccggt gctgttccag
    11161 cagcagatcg gccgcggcct gcgtctggcc aagggcaagg agagctgcct gatcctcgat
    11221 ttcgtcggcc ggcaccgcga ggaattccgc ttcgaccgcc tgctgtcgaa gctcaccggg
    11281 ctgtcgcgcg cgcagctgat cgaggcggtg gacaagggct tcggcctgct gccgccgggt
    11341 tgccacatcc acctgcagcg ccagacccgc gagcaggtgt tgcgcagcct gcgcaagctg
    11401 gtgcagcaga actggcggcg gttgaggacg gagctgcagg cctatgccgc actgcgcgga
    11461 cgcaccgaca tccggcttgc gagcttcctc gccgagcagg cgatcgaact cgacgacctc
    11521 tatcgcagca gcgggcgctc gggctggacc aatctcaagc gcgatgcggg gctgctgagt
    11581 gggccggcgg gcagcgagga cgactacttc gggcggcggt ttggtgatct gctgcacatt
    11641 gacgaccctg cgcggaccga tctgttgtgc tcgctgcgcg agccggacgc ggcctaccgg
    11701 gcgcgcgacg agcgcgagcg gcgcctgctg cagatgctcg cctatcagat cgatgcgcag
    11761 cagcatcaga aggtgagcgg cgaggatttc ctgcagcggc tgcagcatca ccccgagcac
    11821 acggccgagc tcgccgagtt gggcggtgtc ttgcaggcgc gcagcagctt gcgggcgcag
    11881 ccggtgccgg ggctggagga tgtgccgctc tgcctgcacg cggcctatgg catccgcgag
    11941 atcctgaccg cgctcggctg gctgagcccg agtcggcgca caccgttcca ggccggtgtt
    12001 cttgcgctgc acgagcgcaa ggtcgagctg ctgttcgtga ccctggacaa gtgcgagggc
    12061 taccacgagc gcatcgccta tcgggattac gcgatcagcc cggagctgtt ccactggcag
    12121 tcgcagaacg cggcggggcc gcagacgccc gcggggcgtc ggtatctgga gagcccgggt
    12181 aacggctgga cttttcaact ctttgttcgc gcagccaagg gaacgccgta tcgcgcctgc
    12241 ggcccggtga cgctggagcg tgccgagggc gcgaagccga tgagcatcca ctggcggctg
    12301 ggcgtgcccc tgccggggcg gctgttccgg gagttcagca tcttgcgcgg ggcgtgagcg
    12361 gaagggccgc ggcctgcacc gctccttcgg ggcgcggctt ggcggcaggg cgctgcgggg
    12421 cgcgcttggg ggataatcgc ggcatgaacc cgcgccgcct tccctcccgc atcgtctgcc
    12481 tgaccaccga gaccgtcgag gtcctctacg ccctgggcga gcaggaccgc atcgcaggca
    12541 tcagtggcta caccgtgatc cctccgcgcg cgcgcaagga gaagcccaag gttttcgcct
    12601 tctccagcgg cgacctcgag aagatcctcg cggtcgcgcc ggacctggtg ctggggttct
    12661 ccgacatgca ggcggatgtc gcgcgcgacc tgatcaaggc gggcgtagcg gtgcatgtgt
    12721 tcaaccagcg cagcgtcgcg ggcatcctgg cgatgatcga gacggtgggg cggctggtag
    12781 gcgcggaggg ccgcgcgctg gccctggtgg cagagctgga agcgacgatg gacgcggtgc
    12841 gcgcgcgggc ggcggcgctg ccgcggcggc cacgggtgta tttcgaggag tgggacgagc
    12901 ccccgatcag cgcggtgggc tgggtgtcgg agttggtcgc gatcgccggc ggcgaggacg
    12961 tctttgccga gcgcgcgtgc caccccggcg ctgcgcagcg catcctggcg gacccgttgg
    13021 aggcagcgcg ggccaagccg gatatcgtcg tgggctcgtg gtgtggcaag cgcttccgcc
    13081 ccgagcgcgt ggccgagcgc cccggctggg aggcagttcc ggcggtgcgc gacggcgaac
    13141 tgcacgaggt gaaatccgcc ctcatcctgg ctcctggtcc ggtggccatc cgcgaggggc
    13201 tgccggcgct ggcggagatc atcgcgcgct gggcccggcg cgcgttcgac ggttacagcg
    13261 cagcccgttg acagtgcgga attcagcgcg ctataaaaac gtgagttccg caggtcatgt
    13321 cgcaagccgt ggcgcattcc gacgattcca aggccatgct tgcacccatt gcagttcaaa
    13381 accggagggg gtcaagtgaa taaacaggaa ctggttgcaa gcatcgcgga gaaggctggc
    13441 atgaccaagg cggatgcggc acgcgcgctg gacgcgacgg tcgccgcggt gaccgaggcc
    13501 ctccgtcagg acgaaacggt cacactcgtg ggcttcggct ccttctatgt cggcgagcgt
    13561 gctgcgcgca ccgggcgcaa cccccgcacc ggcaagaaca tcaagatcaa ggcggccaag
    13621 gttccgaaat tccgcgctgg caaagggctg aaggattctg taaactagcg gactttgctg
    13681 ctccggcatc cgcgccgggg aaagcgcggg tgcttagctc agtcggtaga gcgtcgccct
    13741 tacaaggcga atgtcggcgg ttcgaccccg tcagcaccca ccacctaacc gcttgagtac
    13801 aaagcgaagc gaaaggcccg gatagcatgc cgggcctttt tgtatttggt gcgggatacg
    13861 gggcaaggtt gcgcccgcgc agcacggaac aaggtccgtc cgcaggccct caatgcaaca
    13921 gcccgtttcc ttgccacccc gcgatccggt ttaaaatatc aatttttgat gtaattgaga
    13981 gaccttgtcg aggcggtcac gccgagcact ttggcgagca ctactgcccg cctgcgctgc
    14041 aggcgcctct cgcctggaca ggcccaagcc aggcttggtc ggccagcggc tcgtcccgtt
    14101 cgccgcctcg ttcgctgtca cccgcggagc ccgccgatgt ccctgtcccg actgttctcc
    14161 ctgcccgcag ccttgtccgc ggggcggcgc gagatggcgc tggggacgct cggggtggcg
    14221 gtggggctgg gatgcaccga gtggatcggc tatctggcgc tgggcggaca ggtgccgtgg
    14281 ttcatcatcc cgatgggagc atcggcggtg ctgctcttct gcttgccggc gagtccgctc
    14341 gcgcagccgt ggccgagcct ggccggcaac ctggtatcgg cgctcgtcgg ggtgggctgc
    14401 taccgctggc tgggcgagac cggtgcggca gtcgcgctgg ccggctgcct cgcggtcggg
    14461 gtgatgttcg tgctgcgttg cctgcatccg ccgggtgggg cggtcgcact gacggcggtg
    14521 ctgggcggcc cgctggtgca tgagctcggc tacggcttcg cgctgatgcc ggtgcttgcc
    14581 aacaccttgg cgatgctggt ggtggccttc ctgttcaaca acctggtcgg gcgtcgttac
    14641 ccgcatctgg cgccgacgcg cccgcagccg cacgacactg ccgatccgct gccgagcaag
    14701 cgcgtcggct ttcgcgcgga agacctcgac gcggcgctgg cctccttcgg cgaggtgctc
    14761 gacgtcgatc gtgacgacct cgaggagatc atggtgcgcg cgcagatgaa cgcgcgccgg
    14821 cgcacctggg gcgcgctgcg ctgcgccgac atcatgtctc gcgacgtggt gagcgcgggt
    14881 ccgcaggcgc cggtggcgga ggcctgggcg ctgctcgcgc accaccgcat caaggccttg
    14941 ccggtggtcg aggagggcgg ccggctggtc ggcatcgtgt cggtgccgga cttcttcatc
    15001 gaccgccaca accccgagcc gcagccggtg ccgcgcatga gcaccgcgcg cgtggtcgcc
    15061 gagatcatga gcgcacgggt acgcagcgcc cgcccagggc agtcgcttgc cgacctggtg
    15121 ggggcgttct cggacggcgg catgcatcac ctgccggtga ccgacgagga cggcaggctg
    15181 gtcggcatga tcacccagtc ggacgtggtg gcggcgctct tcgccggcga gcgcgcggct
    15241 taggcggcgc agccggatcg ttccgcgtgt gcaggagtag cattgcgatg aagtgcgtga
    15301 caagagggag ggaccggaaa tgaccgatcg atcgaacgct gcgcgcaccg agatccgcgt
    15361 cgagaagctc aaggagatgc tcgatttcca gcagcaggcg atcgtgagcc gcatgctgtt
    15421 gaaaaacgcc gccggcagcg tcacactgtt cgccttcgac gagggcgagg gcctcagcga
    15481 gcacaccgcg cccttcgacg cgctgctgat cggcgtggag ggcgaggccg aggtgcgcgt
    15541 cgatgccgac cttcatcggc tgggtgaggg cgcgacgctg ctgattcccg cgggggcgcc
    15601 gcatgcggtg gcgccgtgcg cgcagttcaa gatgctgctg gtgatgctca agggcgagcg
    15661 caaggcctga gcggggaggt gccgcgcccg gccgcgagcc gggtgtcccg tgcggggtcg
    15721 agcatgtcgg cgtcccgggc accctaatgg agagtgtagt catggcgaag aaatttcccc
    15781 tgcatccgaa gaaccccgaa cgcatctgct ggggatgcga caagtattgc tcggtcgatg
    15841 cccttggctg cggcaatgga tcggggcgga cccagcaccc gatcgagctg ttgggcgacg
    15901 actggtacac ctatggcgac tggggcatcg acccggagga cccggcgacg ccgggcagga
    15961 agaaggcgga atgagccggt cggcgagggg gctgtggagg gcatcgtcac gcgcttgaaa
    16021 cctggctgga agacgatcgc ggacgttgcg gaatggattc cgggcgcttg ccgatgggtt
    16081 tgcaaaagaa ttgctgcggt gcagcaaaaa agagttgacg accgaattcg gggcgctata
    16141 atcgactcca ttgtgcggtg cagcaaagcg aagccggaag gttttcgggc aacagggccg
    16201 catggaccgc aggatttttt acgcttcatc gactccactg caattcacca aggaaaccag
    16261 ccatgaccaa gatccagacc cccgagcagt tcgccgccgt cggccaagcc aacctcgaag
    16321 ccatgatgtc gctcgccaac agcgccatcg cccgcgccga gcgcctggcc gaactcaacc
    16381 tcaacaccgt gcgttcggtg ctcgaagaca gcgtcgccac cacccgcaag ctggccgaag
    16441 ccaaggaccc gcagcagctc gccaagctcc agggtgagct caccaagccg atgctcgaca
    16501 aggccgtcgc ctacgcccgc agcgtccagg agatcgccac cgaaggccag caggaagtgt
    16561 cgaacctgtt cgagaagcag atcgccgacc tgaacaagcg cttccacgag atgctcgagc
    16621 aggctgccaa gcaggccccc gccggctccg agggcgtgtt cgaggccgtc cgttcggcga
    16681 tgaacaccgc caacagcctg tacgacaacg ccagcaaggc cgcccgccag gctgctgaag
    16741 tcgccgaagc caacatggcc gccgcgaccg aagccaccgt caaggccgtc agcgccgcga
    16801 ccaagaagta atcgcgccac cgccaggcgg cgtccgcgcc gcctcgcagc aaaaggccgc
    16861 ccggcatccg ccgcgcggcc tttttgtcgt ggctgcggtg gttccggggc aggtcctggc
    16921 ttgcgcagca gcgccggcgg ccgagaatcg agcggcgcag gaagccgcac gcatgcctcg
    16981 ccctgcttga caggccgatc cgcgatcctg cgcttgacgc ccggcggccc gccttctaga
    17041 atgcggcctc ttttcggaag ggcggttagc tcagcggtag agcactgcct tcacacggca
    17101 ggggtcactg gttcgatccc agtaccgccc accacccgca gcggtggtgc accttcctga
    17161 aaaacctgcg tcaggctgcg gtttgcgcat cccgatcagg gcggttagct cagcggtaga
    17221 gcactgcctt cacacggcag gggtcactgg ttcgatccca gtaccgccca ccagacaccc
    17281 gaaaacccgg ccctcgcgcc gggttttcgt tttgagcgcg caggcgattg cttcttcctc
    17341 ctcgtacgcc tccccggcgc ccggccatgc ggttacgatt ggacctcttc cagaccagtt
    17401 ctgccggagc ccgccgatgt ccgcccgatc catccgctcg tccgccgccg caccgtcgtc
    17461 tcatgatcgc cggttgccgg cggtcgaata ccgcatccgg ccggcgaacc ccggtgccca
    17521 cctcttcgag gtgagctgca cggtggccga gcccgatccc gcaggacagg tcttcagtct
    17581 gccggcgtgg atcccgggca gctacatgat ccgggagttc gcgcgcaaca tcgtgcgtat
    17641 ccgcgccgag gccgacggcg cgccctgcgc gctggagaag ctcgacaagc acacctggcg
    17701 cgcggcaccg gtgcggggag cacgctctct gagcgtgcat tacgaggtct atgcctggga
    17761 cctgtcggta cgcaccgccc acctcgacac cacgcacggc ttcttcaacg gcaccagtgt
    17821 cttcctcgcg gtggcaggcc gcagcgacgc gccctgcgtg gtgaccatcg agcgccccga
    17881 gggcgagagc ggtcgcgact ggaagctcgt caccgcgctc ccgcccgagc atgggcgccc
    17941 cggccaggcg tgccgcttcg ggcgcttccg tgccgcggac tacgatgagc tgatcgacca
    18001 tccggtcgag atgggtcgct tcacgctggc gcgcttcgag gccgcgggcg tgccgcacga
    18061 catcgcgctg accggccgcc acgactgcga cctcgagcgc ctgtgcgccg acctgcgccg
    18121 ggtgtgcgaa tggcagatcg cgctcttcgg cgcgccggcg ccggtggact actacgcctt
    18181 tctcaccatg gtggtgggcg agggctacgg cgggctggag catcgtgcgt cgactgcgct
    18241 gatctgcagc cgcgccgagc tgccttggaa gggcatggag ggcctgcccg acggctacaa
    18301 gagcttcctc gggctgtgca gccacgagta cttccacacc tggaacgtca agcgcatcaa
    18361 gccggcggcg ttcacgccat acgagctcgc gcgcgagaac cacacccggc tgctgtgggc
    18421 cttcgagggc ttcacctcgt actacgatga tctcgccctg gtgcgcagcg gcgtgatcgg
    18481 catcgacgac tacctcgggc tgctcggcaa gaacatcgcc aacgtgctgc gtggcagcgg
    18541 ccgcctcaag cagagcgtgg cggagtcctc gttcgacgcg tggaccaagt actaccgcca
    18601 ggacgagaac gcgcccaacg ccatcgtcag ctactacgcc aagggcgcgc tgatcgggct
    18661 cgcgctcgac ctgcagctgc gcgccggcag cgagggtgcg gcgagcctgg acgacgtgat
    18721 gcgcctgctt tggcagcgcc acggcctcac ggggatcggc gtgcccgaag acggcatctt
    18781 cgccgcggtg cgcgaggtgg gcggcgaacg cctcggcgta cgcctggcga agtggctgca
    18841 gaaggcggtg gagggctgcg aggacctgcc gctggcgcgc ctgctgcggc ctttcggcgt
    18901 gaccctgcgc gccgacgctg cgggaagcgc gccggtgctc ggaatgaagc tcgccgcggg
    18961 tgggggcgag gcgaaggtcg ccagcgtgta cgacgacggc ccggcgcagg ccgcgggcat
    19021 ctcggccggg gacgtgctga tcgcgctcga cgggctcagg atcgcgaacg ccaaggcggt
    19081 ggacgaactg ctcgcccgcc ggcgcgcggg cgacgaggtg gaactgcacc tcttccggcg
    19141 tgacgagctg atgagttttc gcgcggtact cgcggcgccg cccgccgagc gccaggagct
    19201 caagctcgcc ccgcgtgccg acagcgaggc tctcaggttg cggcggggct ggctgggggg
    19261 ctgatgcggc gcgaggtcat gcgttcaggg tgggcgcgca ctgccggatg gtgagacggg
    19321 agcgggcgcg cgggtgcggg agcacccgtc gcggagtgcc tcccgctcag gccgcgggtg
    19381 tggcggtggc agccgggaac agtttgggct gccagtagcg ccaggcgagg aagcctgcga
    19441 gcgccgcgat gatcagccag aagccgacgc cctgccagaa ggcgatcggg tcggtggcga
    19501 ggaagtagtc gcgcggcggg cgcacgaaat ggatgcgtcc ggtgatgagc gcgcgcaccg
    19561 cctgcgcgat cgccgccagc gcgggcatga accacaccag caggccggca ccgacgatga
    19621 cgcggtcgag cagcggcgtc gtccggctgc gcgggctata gacgctgcgc accccgaacc
    19681 acaccgcgac caggaagccg agggccgcgg cgagcgggcc gatcgccatc gcgccgccga
    19741 gcagggtggc cgccgcgagg aaaggaattc cctcgagtcg cacgatctcc ggccacagcc
    19801 gctcgagctg gctgaacaac agccacgagg cgggcagcgc gaccacgcag accagcagcg
    19861 cgaacaaggc gcgccggcgg tcacggtcgc ccggcggagg agtggagctg cggttggagg
    19921 gcgcggaaac ggcgacggtg ggggaggtgt cgggcatgga gtaggggcgt ggagcgaatt
    19981 ggaagccgga caagtgtact acgcccgtcg ccccgatctc ccggcgcggg ctccgtgagc
    20041 ccttgcaaga cgccgtcagc cgaaataccc atgcacgaac cattgtcccg gcgcatccag
    20101 gctctcgaag atccagcaca gcacgttgtc ggcgtcgcgc gcgaggtagt agtcacggcg
    20161 cacgggcatg ccgtcccacc agccggtctc gatgcgttcg gcggcgccga gcagggtgta
    20221 gcggggggcg gcgatcgggt gcggcgcggg cagcagccag agcgggcgca gtctggcggc
    20281 ggtgcttgcc ggcggggggg gcgtccgcgt cgagggggca cctgggggtg cgtcgcggcg
    20341 ggcgcgtggg gggacggccg gcgcggacgg tctggcattt cgccaggcgg cctcgggacg
    20401 gtgatcggcg cgaagatcga ggcgctgcac gccgttctcg ccgagccgag cttgcaggcg
    20461 ggcgagcagc agggcggcgt cgtcgccggc ctgggcggga tcgccgaaca ggtcggtgcc
    20521 gcggggatcg gcagggagcg ggcgttccgc gctcagcgtg atcgagtcga cctcggcgga
    20581 tagttcgagc acggccaggc gttcgcgcac gatcagggcg aagcgggcct cgtcgcggct
    20641 cgggcggccg agcgcgaact cgatctcggt gggtgctcgc gagccgtggc cgaagcgcag
    20701 gcagaagcgg tcgatcgctg cgtggcgggc gtcgagccag gcggcaaggc tggcgaaaag
    20761 gcggcgcgcg gcgaagagca gggcctcggc gtgaagttcg ggcgcgggca gggcgagctt
    20821 gtggtggaag cgcagcggtg cctcgaacca ggggcgcgga tcggcgagct cgccacgtgc
    20881 ccgggcgatt gtccggacgg ccgcctgcgc gccacggcgg gcgagcccgg cgggcggcag
    20941 gcagcgaagc tcgcccaggg tgcgcaggcc gagcccggcg agcaactcca gcgtggcggc
    21001 gtcgcaggcg tcctcctcgc tcagcagttc aatcggcagc gggtcgagcg cggcgcgcca
    21061 gtctcgcgcg tcggcgtggg tggcgtcggt ggagcagggg gtgtggatgg gcgcgttgga
    21121 tggcgcggtg ggggcggatg ggaaggaggg ggggatcggt ctcgaaggtg ccgcaccttc
    21181 ggcaggagcg cctgtccgtg ccatccagcg cgccgccagc gctgtgggcg cgcagcccag
    21241 ccgggccgcg aagcccaggc cgccaaggcc ttcgcgcacg gcggcctcga tctgggtcac
    21301 accgccgaac aggcgcaggc aggaggagat ctccagcagc accgcgtcgg gagcggacag
    21361 gctgatccgc ggactgaagc gcccggccca ggtggcgatc tcggcgaggg cctcggcctc
    21421 gcgcgccggc tcgcgcggct gcaggcgcag ttcgggcagc agggcgaggg cgctcgcggc
    21481 gcgttgtccc gcttcgatgc cggccgcgct cgccgccgcg ctggcagcca gcacccggcc
    21541 ccgcggcgac aggatcgcca gcggtggggc ctcgcgcacg ccgcgggtga acacctgcag
    21601 cggcagggcc ggcaacagga tggccagcca caacatggat tcgctccggt tgaatgttgg
    21661 tgaatgaagc gaccgtggtc cgtgatcgaa ggccgtaatt cgcgcctgcc ggcgctccta
    21721 cataaaccgg cgcggctccg gttctggtgt aggagcggcg gaagccgcga acnnnnnnnn
    21781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    21841 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nngtcgaggt tgatcgtgag cccgagggcc
    21901 gtaattcgcg cctgccggcg ctcctacctg aaccggcgcg gctccggctc tggtgtagga
    21961 gcggcggaag ccgcgaacag cggtgtgccc gactccgtcg aggttgatcg tgagcccgag
    22021 ggccgtaatt cgcgcctgcc ggcgctccta cctgaaccgg cgcggctccg gctctggtgt
    22081 aggagcggcg gaagccgcga atcgctgccg atgccaggtg agagagcgag tacgagcgct
    22141 gcggtggaga gcggtccgcg gcgcttgagg atgcgtagct gcaggccttc ggggtggggg
    22201 gcgagcgcga tccgcaacac cgcgggcgag ggctgcgcgg cgacgctggc gtggcggaag
    22261 aggaagagcg gggtggcgct ttcctcggcg gcgagctgca ggcggcgcag tgcggcgttg
    22321 tcgatgcgct gtggccaggc cagcacgcag gcgcagctgc ccgacagcag ggcctgtcgt
    22381 gcagcccaga gcaggtcttc acggcgttcg ggacgcacga cgagcaggcg cgacaacggc
    22441 acgccggcgc tcgccagcgc aggggcgtag ggcagcagcg gcggggcgat gcagacgatc
    22501 cagcgtgcgg agggggtggc gccgagcagt ggcagcagca ggctcagctc gccgacgcca
    22561 gggcggtcgg cgaggagttc gatgagcgca ccggccggcc agccgccacc gggcagctcg
    22621 gcgtcgagcg cggcgaagcc ggtcggcagc accgccccgc cagcctgtgc gagccggctc
    22681 gcctgccaca cgctgcccgc aggcaggccg gcaagcacgt catgcgtgcc ggtggcgacg
    22741 ggaacggcgg cgtgcagcga cgcgtcggcg tggcgttgga gcgggagggc catggtgggc
    22801 gcggcatcgg gtcgctcagt ggtccttgcg gatcagcccc accatgacgc cttcgatgac
    22861 cagcggctcg cggcgggtgt ccacgacgat cggcgcgtaa tccgggttgg cggggagcag
    22921 ctcgaccacc gcccccttgc gctgcagggt cttgacggtg acgtcgtcgt ccacccgtgc
    22981 gaccacgatc tggccgttgc gcgcctcgcc gttgcggtgc accgcgatga ggtcgccgtc
    23041 gaggatgccg gcgtcgcgca tgctcatgcc gcgcacgcgc agcaggtagt cggcccgggg
    23101 cgagaacagc gcggggtcga gttggtagcg cgcctcgacg tgctcggcag cgaggatggg
    23161 gctgcccgcg gcgacgcggc cgaccagggg caggccgagc gcctcggcca ggcggatgcc
    23221 gcgcgcgcgg ccttcctcga gcaggatcgc gcccttggcg gcgagcgcgc gcaggtgggt
    23281 ctcggcggcg ttgggcgagc ggaagccgaa ggcggtgcac acctcggcgc gggtgggcgg
    23341 gcggccttcg gactcgacgg tggagcggat gaagtcgagg atttcctgct ggcgcgcggt
    23401 gaggttctcg ctacgggcgg tcatgacagc ctccatggga tggctgtaat tttaaacagt
    23461 cccgcgccgc tggcaagggg aattcagggg aattcagggc agcagcaccg ccgctccctg
    23521 cagcgcgccg cggcgcaggc gcagcagcgc ctcgttggcc tcttcgagtg gaaagcgggt
    23581 gacctcggtg cgcaccggca ccttcggcgc gagggcgagg aactcgtcgc cgtcgcggcg
    23641 ggtgaggttg gccaccgaga cgatgcggcg ctcgccccac aggatgtcgt aggggaaggc
    23701 ggggatggtg ctcatgtgga tgcccgcgca caccaccgtg ccgcccttgg cgacggcgcg
    23761 tagcgcggca gggacgagct cgcccgcggg ggcgaagatc agcgcggcgt cgagcgggtg
    23821 gggcggcagt tcgtcacccg cgcccgtcca gcaggcgccg agctgacggg cgaaggcctg
    23881 gctttcattg tcgccgggac gggtgaaggc atacacctcg cggccctgcc aaaccgccac
    23941 ctgggcgatg atgtgggctg cagcgccgaa gccgtagaga ccgatgctgc gcgcgtcgcc
    24001 ggccatctcc agcgcacggt agccgatcag gccggcgcac agcagcggcg cggcctcggc
    24061 ggcgtcgagc gcctcgtcga tcggaaagca gtagcgtgcg tcggccacgg tatattcggc
    24121 gtagccgccc tggatctggt agccggtgaa gcgcgcgtgg tcgcagaggt tctcgcggtg
    24181 gctggcgcaa aagccgcagt ggccgcaggt ccatcccagc cagggcacgc cgatgcgctg
    24241 ccccggcgcc atgccggcgt cgtcgccgac gccttcgccc agctcgacca cgcagccgat
    24301 gatctcgtgg ccgggaatca tcggcagcac tgggtcgggc agctcgccgt cgatgaggtg
    24361 gaggtcggtg cggcacacgc cgcaggcctc cacgcgcagc agcacctggc cgcgagcggg
    24421 gcgcggcact gccaggcgca ccgcgcgcaa ggcctcgccg gggcgttcga gctgcatcgc
    24481 gcgcatggtg gaggggaggc tggcaggggc gttcggatgg ggccggggca tgcttgcggt
    24541 ctccaggaaa ggcggaacga tggtgcgctg cgacttgagt acggcccaga tctgggctat
    24601 tcgttggtca cggtgtcggc tggcggcacc cgacacgacg acaaggaaaa gggaggaaga
    24661 cccccatgct cgaccagtcc gaagcccgtg gccccggcgg tagtgttcgc ctggggtctc
    24721 ggctagaatc cgggccacat cagggagaac acatgctgca gagcggagac atcgcccccg
    24781 cgttttcgtt gccggatgcc gacatggaaa ttttcgacct cgcgtcggca gccggcaagc
    24841 acaatgtggt cctctacttt taccctcgcg acaagacccc gggttgcacg cgccaggctg
    24901 cggacttcag cgaccacgag gacgagttcg cccgccacga ctgcatcgtg gtcggtgtga
    24961 gtccggacga ctgcctgacc cacgccgagt ttcgcgacca ggaagggctg tcgatccgcc
    25021 tgctctccga ttccgacacc gaggtgtgcc ggctctacaa cgtgtggcag gagcgcgaag
    25081 tcgacgggat gaagaagatg ggcgtgcggc ggtcgacctt cgtgatcgac aagcagggca
    25141 ggatccgcca cgcgctctac gatgtgacac cccgcggcca cgccgccgcg gttttcgaac
    25201 tggtcaagga actggaaccc cggaatgcaa aacgaaatcg tcaagaatag cgtggtgacg
    25261 ctgaagtaca ccgtgcgcga ccccgaaggc gcgatgatcg acgacggcga acacccgctc
    25321 gtctatctgc acggcggcta cgacggcatc ttcccgctgc tggaagaagc cctgcacggc
    25381 aagaaggtcg gcgaacagct gcaggtcaag ctgcagcccg aggacgcctt cggcgactac
    25441 gacgaggagc tcatcctggt cgaggacgcc aagctcttcc cggacaacat cgagatcggc
    25501 atgagcttcg agcgcgtctc cgaggacggc gaggaagaca tgatctaccg catcaccgac
    25561 atcgccgacg gcaaggtcgt ggtcgatggc aatcacccgc tggccggcgt ggcgctcgtg
    25621 ttcgacgtca ccgtcgccga ggtgcgcccg gcgagcgccg aggagatcag ccacggccac
    25681 gtgcacggcc ctggtggtca ccaccaccac tgatcccgca gatgtccgca aggggccgcg
    25741 caagcggccc tttcgacatg tgggcggccc atgtggcgcc atgcgcggca ggggccgtcc
    25801 gcgtcccatc gcttcgacct gctgctgcac ccctctgagg gtcgccccct gcgtatgaac
    25861 gctccgctcc ccgccgatct ccccgaagcc gcgaccgcgg cgctgctgca cgtcgaaggc
    25921 ctgggcgtgg cgatcgcgcg caccgatggc gaggaggtcc gcccggtcga tggggtggat
    25981 ttcgccatcg ccgcgggcga gacctttgcc ttgctcggcg aatcgggctg cggcaagtcc
    26041 atgaccgcgc tcgcgctcgc ccgcctgctg cccgacggcg gccgcatcgc cgccggcagc
    26101 gtgcgcctgg gcggcgagga cctgctcgcg ctgcccgagg cggcgatgcg gcgggtgcgc
    26161 ggcgggcgca tcggcatgat cttccaggag ccgtccacca gcctcaaccc ggtgatgagc
    26221 gtgggcgcgc agatcgccga ggcgctcgcc gcccacggcc tgcgcggcga ggcggcgcgc
    26281 gtcgaggcct gccgcctgct cgccgcggtg ggcatccccg acccagagcg ccggctgcag
    26341 gagtttccct tccagttctc gggcgggatg aagcagcgcg tgatgatcgc gatcgcgctt
    26401 gccggccgtc cgcgcctgct gatcgccgac gagccaacca ccgcgctcga cgtcaccatc
    26461 caggcacagg tgctcgatct gctcgccgca ctgcagcggc gcgagggcat ggcgatgctg
    26521 ctgatcaccc acgacctcgg cgtggtcgcg cgcgtcgccc accgcgtggg ggtgatgtat
    26581 gccgggcagg tggtggagac cggaccgcgc gcggccttct tcgccacgcc actgcatccg
    26641 tattcgcgca agctcttcgc cgcgctgccc gaggcggcca agcgcggcgg ggtgctcgac
    26701 gcgcccgtgg gcagcgtgcc gccgcccgac cgccacttcc ccggctgtcg cttcgccgaa
    26761 cgctgcccgg cggccttcga ccgctgcgac gaggaggcgc cggcctggca cgcggtcggc
    26821 atgcaggcgg tgcgctgcca tctgtacgag ggtgtggcgg tgccgcgccc gctcgtggcc
    26881 acgctcgcgg gcgccgtcga cacggtcgcc gcgcgtccgg cgcagagcgt gctcgaggtc
    26941 gccgagctgg cggtgcattt tccggtgcgc aagggcttcc tgcggcgcac cgtcggccat
    27001 gtgaaggcgg tcgatggggt gagcctgcgc ctgcagcccg ggcgcacgct cgcgctggtg
    27061 ggcgagtcgg gctgcggcaa gaccaccgtg ggcaaggccc tgttgcgcct gatcgagccc
    27121 accgccggcc gactatggct cgacggcgag cgctacgaca cgctgccggt ccaggccctg
    27181 cggccgctgc ggcgcgcggt gcagatggtg ttccaggacc ccttcgcctc gctcgatccg
    27241 cgcatgcggg tgggcgagat catcgaggag ggcctggtgg cgctcggcat cggtgccgat
    27301 caccgtgcac gccaggcccg cgtggccgag ctgctcgagc gcgtgggcct ggcggcggag
    27361 atgcgctggc gctatccgca cgagttctcc ggcggtcagc gccagcgcat cgcggtggcg
    27421 cgtgcgctcg cggtgtcgcc gcgggtgatc gtgtgcgacg agcctaccag cgcgctcgac
    27481 g
//
LOCUS       DAOTIN010000039        26660 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_2094_length_26660_cov_8.907649, whole genome shotgun sequence.
ACCESSION   DAOTIN010000039 DAOTIN010000000
VERSION     DAOTIN010000039.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 26660)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 26660)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26660
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2094_length_26660_cov_8.907649"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(216..1106)
                     /locus_tag="P5537_07960"
     CDS             complement(216..1106)
                     /locus_tag="P5537_07960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004376114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate kinase 2 family protein"
                     /protein_id="HRV78015.1"
                     /translation="MSKHKPIDIAEFRVRGGRKIDLADWPTRVHALYDSKSDYQERLD
                     AGTARMAELQEMLYAHDRYSLLVIFQAMDAAGKDGAIRHVMSGINPQGCQVFSFKHPS
                     ATELDHDFMWRTHCALPERGRIGIFNRSYYEEVLIVRVLPEILRGQKLPDETLAARDF
                     WGDRFQSIVDAEAHLHRNGTRIVKIFLHLSKDEQRDRLIARIDEEDKNWKFDEGDIEQ
                     RKHWDKYMAAYADCLRATSTPDCPWYVVPADDKKNARLIVSQILVDTLAGLDLHYPET
                     TAARREKLLEIRRQLESGEV"
     gene            complement(1186..2859)
                     /gene="mgtE"
                     /locus_tag="P5537_07965"
     CDS             complement(1186..2859)
                     /gene="mgtE"
                     /locus_tag="P5537_07965"
                     /inference="COORDINATES: protein motif:HMM:TIGR00400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HRV78016.1"
                     /translation="MNDEMRTDDRPADGKAASADTRPLTLSEQIVKALGEGRNKRVRK
                     LLQRLHPAKTAALLEHLSPRQRLVLWQQIGGSLEQRVLGHLSPELRPAMLRESREDGE
                     AAPARPEGEPEGASSELQAVRQALEAGKLKRVGKLLHRMHPAKVAGLLEALPPAERSQ
                     AWSMVETERAGRVLSFLHDEISTTLAQELDLEDLIAAVQHLELDDLVDLIQTLPPDLG
                     NRLVHATSGVRREQLESMLSYPEESAGGLMNADTIEVRAEVKVGTVLRYLRLLDKLPP
                     RTDVLMVVDRRGTYQGVLSLSDLVTAEPDTHVADIMRTDVAAIPVDTGSLELARMFQD
                     QDLLTAPVVDAAGRLVGRITADDVVDLIREDSDRAVMQMAGLDDEADMFAPVLVSSRR
                     RAVWLGINLLTAFLAAWVIGQFQGTLEQIVALAVLMPIVASMGGIAGSQTLTLVIRGL
                     ALKQVQKGNIRILLNREVGVSIINGLLWALVVAALAVAWFGDWGIGGVIAAAILLNLL
                     CAALAGLAIPLILERMGIDPALAGSVILTTVTDVVGFFAFLGLATVLLL"
     gene            complement(2856..3665)
                     /locus_tag="P5537_07970"
     CDS             complement(2856..3665)
                     /locus_tag="P5537_07970"
                     /inference="COORDINATES: protein motif:HMM:NF013117.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HRV78017.1"
                     /translation="MLEDSPKLAGLFNSLDRSAWIEIAAIAAVAVLLVRASQRALPWI
                     ANRLHGRARHYLLASVPLLRLVLIVIASGLILPIVIEPSLRNMVALLGAAGLAIGFAL
                     KDYVSSLIAGVVSAFEQPYRPGDWVELDGHYGEVVHVGMRTVSLVTVDDDTIIVPHLK
                     LWTSAVRNANNGSPVLQCAANFLVHPQHDARRAREVLEDVALTSPFLYFDAPVVVSIA
                     EETWGTRYTVRAYPVDPRQQYRFVSDLTVRGREALARIGAEALLPQVSVLS"
     gene            complement(3668..4957)
                     /locus_tag="P5537_07975"
     CDS             complement(3668..4957)
                     /locus_tag="P5537_07975"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78018.1"
                     /translation="MTDASHPRRAPPSPWRIVTLDEHVRPTDSQPAAMRRRWRALARL
                     LRSEDPDQAHARAETELRSLPNVRLEHLAPALDWSAAAEALASFLRDESARPPDASHA
                     RVRVLVCPPHCAHEQILAHWAARHGARILDLPDEADVLADTPRWLESLPPPPTDDRDA
                     RPWVLPRLERCFLRHAQGLTLLRSFLAAAFSGRLGPGLIGCDSWAFAYVQRIWPLPAG
                     VALTLQGFDGSALAEHFIRPFCSGVHAVEFRSARSGKPLLPEPDSDGEDRDAAIAPEL
                     RQLAAHVRGNPGLAWHYWRERLRSAPQARPAQDGESGTAPSAADTASRGMTLGEDVVW
                     LGEDIAPPGLPADSGDDHAFIFHALLIHRSLPTALLAHLLPTPEPRLQSLLLRLEALG
                     LVARDGGGEAARWQVPPLAYLTVREFLRSRSYLTDAF"
     gene            complement(4995..6920)
                     /locus_tag="P5537_07980"
     CDS             complement(4995..6920)
                     /locus_tag="P5537_07980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HRV78019.1"
                     /translation="MTQDPLFVLAILAATMGMFLWGRWRHDMVAAGALLACVVGGLVA
                     PDAAFAGFGHPAVITVACVLVLSRALQTSGAVDALSRRLLPSGAGLAASLAALVAMGA
                     LLSGFMNNVGAMALLMPVAMQLAARLELPPGRVLMPLAFGTILGGMTTLIGTPPNLIV
                     SGFRAQQGAGAFGMFDFAPIGLAVALAGGLFIVLLGWRLVPAREKASTEGFETGAYVT
                     EVRVGRESKAAGMFLREIEARLDDAGAQVIGLVRNEVRMTAPQSGRKVHAGDILVIEA
                     DVEALPEVLSGLGLELEEAGSSNEDEQAGSAAATADAEGDEARAVQPASAKKGKKQAD
                     GRDEEAPPEAARDSDKPSPDNEIVLMELVVRPEASLINRSARDLALRTRYGLNLLAVS
                     REGTRAKARLRTLKLKAGDLLLMQGPVEALNEFAADHGCVPLAERELWIPDRRKAWTA
                     GVIMAAAVAAAALGLLPAAIAFALGVLASMALRTVALRSVYESIDWPVIVLLAALIPV
                     AGAMEASGAASLVARVLLEDVARGNAVVALATLLIVTMFLSDVMNNAATAAVMCPIAI
                     GTANALGASADPFLMAVAIGASCAFLTPIGHQNNTLILGPGGLRFGDYWRLGLPLEVL
                     VAAVAIPMLLLVWPLHG"
     gene            complement(7324..10026)
                     /locus_tag="P5537_07985"
     CDS             complement(7324..10026)
                     /locus_tag="P5537_07985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-transporting P-type ATPase"
                     /protein_id="HRV78020.1"
                     /translation="MSPRTAPLSLLEHAHARTADEVLSALDSCPAGLSADEAARRLAE
                     VGPNRLPEPPRDGLLKRFFKHFNDVLIYVLLGAAAITASLGHWIDTGVILGVVVINAI
                     IGFIQEGKAEEALAGIRKMLSLRADACRDGQWSAVDADGLVPGDVVRLRSGARVPADL
                     RLIEATNLRIEESALTGESVPADKTTEAVAADAGVGDRLGMAYSGTLVAAGRGTGVVV
                     ATGPDTELGRINRLIAEVQTLQTPLTRQMARFSKILSIVIVGLAALMLGVGLAVHEQP
                     LAEVFLAAIGFAVAAIPEGLPAILTITLALGVQRMAQRNAITRKLTAVEALGSVTVIC
                     SDKTGTLTKNEMTVRHVLTRGGFYEVSGTGYRPEGEITLEGEVASLARHGHLQALIEV
                     VAVANDTHVAEEDGQWKVTGEPTEGALRTLAHKAGFDAGAHERHASIPFESANKFMAT
                     LNTAPGGQRRILLKGAPDRLLERCRHELGAEGELEALDRAFWEAHIDALSGEGLRVLA
                     AAARDVPASKDALAVEDLEEDMVFLGLIGIIDPPRPEAIEAIRSCHEAGIRVKMITGD
                     HAGTARAIGIEMGLGAADTLKVITGAEIEAASDEELQRIAHDCDLFARTSPEHKLRLV
                     KALQARGEVVAMTGDGVNDAPALKRADVGVAMGIKGTEATKEAAEIVLADDNFSTIER
                     AVEEGRTIYDNLRKAILFTLPTNGAQGLVMLAAVVFGLTLPLTPVQILWVNMVVAVTL
                     ALALAFEPAEPGVMQRPPRKPGGSIMDGTMLMRVGFVSLLIGGATIASFEYSLLQGME
                     LGTARTMAVNTLVVAQAWYLFNSRFLTASSLALSRMFTNPGAIVSVGLLGLLQLGFVY
                     VPAMNTWFGTTPLPLEAWGPPMAIGVLVFLIIEGEKALLRARRR"
     gene            complement(10219..11634)
                     /locus_tag="P5537_07990"
     CDS             complement(10219..11634)
                     /locus_tag="P5537_07990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HRV78021.1"
                     /translation="MRKRDTTLTTDQKALAINLDKYKYGSIVEIGAGQEVARRFFHVG
                     AAAGTIAKTMSAYDMAVSDDIYGHVDRYVSRARLLQMLDKEFTQVVARLAHVRPRNTT
                     FFAYAATVTARSFKQKNECHGWVGIRLQLHPGAEPSDVVMHVRMLDNDNALQSEALGI
                     LGVNLIHGAFFHHDQPEWVVEGLADGLGSERIEVDLIHFSGPYFEEVENRLMNLHLIR
                     SWLTRAVVFNPQGEVVVPGELLYRKPVMVMRGSFKPVTLVNVDMMSAGVRQFSQLAAV
                     DDGEIVSLAEITMNSLISGDNVDGADFLARIDLLASQGYTVMISDYVRFFRLRAYLRR
                     YTQKPIGIVLSVRDFAFLFDEKYYEGLEGGILEAFGKLFPDNTHVYVYPSRPRGTDAS
                     ATVTLDNVAVPANLRHLLAHLKENDKLVAVQPHDDTHLHIDIGEVLAGLRRGRGEWEA
                     DVPEAVAQRIIDKRLLGYDTE"
     gene            complement(11679..12500)
                     /locus_tag="P5537_07995"
     CDS             complement(11679..12500)
                     /locus_tag="P5537_07995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HRV78022.1"
                     /translation="MSQPSTRLQARYGQESVPADIALNPLIEHLLDHRSVRAYLPDPV
                     TDAELAAIVAAAQSAASSSNLNVWSVVAVRDAERRARLAELAGNQAHVREAPLQLVWL
                     ADLARLRRIADGLGRPAEGLDYLEMFLTGVIDAALAAQNGAAAAESLGLGMVYIGGMR
                     NRPEEVAELLGLPPGVFAVFGMCVGRPDPARPADIKPRPPQAVVLHHERYALEAQDAG
                     IAAYDRAMERFYAEQKMNVHGTWSVHSSKRIAGPETLSGRHRLIEALNALGFALK"
     gene            12842..14533
                     /locus_tag="P5537_08000"
     CDS             12842..14533
                     /locus_tag="P5537_08000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HRV78023.1"
                     /translation="MSAVNEFLAARDFLLQHRSDYATAYAGFKWPRLKEFNWALDYFD
                     AMAEGNDNPALWIIEEDGRESRLSFAEMSARSNRVANWLRKQGVKRGERILIMLGNEV
                     PLWETMLAAIKLGAVVIPATTLLTPEDLVDRVERGQVRHVVIGKAHTDKFENLPGNFG
                     RIAVGGAPAGWKAFEEAAAESDVFTPDGVTRVDDPLLLYFTSGTTSKPKLVLHTHQSY
                     PVGHLSTMYWIGLKPNDRHMNISSPGWAKHAWSCFFAPWNAGACVFLYNYNRFNAAAL
                     LDVLVKYEVTTMCAPPTVWRMLIQQDLAAVKTKLRELIGAGEPLNPEVIDQVKKAWGI
                     TIRDGFGQTETTAQIGNTPDQPLKPGSMGRPLPGYKIALLDADSKPSVEGEVSLVMGE
                     HRPVGLMVGYSGDPAKTAEVMRDGHYRTGDVASIDEDGYITYVGRADDVFKASDYRIS
                     PFELESVLIEHPAVAEAAVVPSPDPLRLAVPKAFVILVAGQEPSRELAKDIFAFTRER
                     LAPYKRIRRLSFADLPKTISGKIRRVELRKAEEARGEAARGELEFFEEDFPELKG"
     gene            14614..14712
                     /gene="ffs"
                     /locus_tag="P5537_08005"
     ncRNA           14614..14712
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="P5537_08005"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(14788..15690)
                     /locus_tag="P5537_08010"
     CDS             complement(14788..15690)
                     /locus_tag="P5537_08010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HRV78024.1"
                     /translation="MVDKVARLHFQPASPAGALRALSGWLIAVTGLALLVAQLARSVE
                     GFELAVSGAVAGGAMAAAATALGAVPLLVVRRIGASVQGMLLGFGAGVMLAASVFSLL
                     LPGFEAALAQTGTETGAALLVAFGVLLGAGGLLAMDRALPHTHFPEGRRSGAAVWLFV
                     FAIAVHNIPEGLAIGVAAGLEGTGAGSGDAVAAGISLQNVPEGLIVAIALVAAGYGRW
                     LAFGVAAVSGLIEPVAAIAGSVMVSVSATILPWGLAGAAGAMLFVVSHEIIPESHRRG
                     HETLATGGLMVGFVMMMLMDTLVA"
     gene            15903..16805
                     /gene="argB"
                     /locus_tag="P5537_08015"
     CDS             15903..16805
                     /gene="argB"
                     /locus_tag="P5537_08015"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003991 - acetylglutamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HRV78025.1"
                     /translation="MTQPVHQQDVTPARKAEILAEALPYIKRFFDKTIVIKYGGNAMT
                     DPHLKDCFARDVVLLKLVGLNPVVVHGGGPQIENLLTRMGKKGEFIQGMRVTDAETME
                     VVEMVLGGQVNKEIVNLINKHGGKAVGLTGKDAGFIRAKKLLMQKHGAPEGDLIDVGQ
                     VGEITGIDPSLISFLDQGDFIPVIAPIGVGEDGETYNINADVVAGKLAEILKAEKLVL
                     LTNTPGVLDKAGNLLTGLTPRQIDDLVADGTLSGGMLPKIGSALDAARNGVKSVHIID
                     GRVEHCLLLEILTDHGVGTMIKSK"
     assembly_gap    17035..17134
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(17243..17680)
                     /locus_tag="P5537_08020"
     CDS             complement(17243..17680)
                     /locus_tag="P5537_08020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HRV78026.1"
                     /translation="MSNPLTRRTDPLDDFFRGFFVRPVDFGGQQLATPGTDAPQMRVD
                     VKETAQGYEVHAELPGMKKEDIHVHIDGPVVSISAERKQEKEIKDGEKVLRTERYFGK
                     VSRSFQLGQEIDEAAASAKFNDGVLELHLPKKAEVQARRLTIE"
     gene            17839..18042
                     /locus_tag="P5537_08025"
     CDS             17839..18042
                     /locus_tag="P5537_08025"
                     /inference="COORDINATES: protein motif:HMM:NF025733.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich CWC family protein"
                     /protein_id="HRV78027.1"
                     /translation="MNETTNVCPRCGASFTCGMRAGEAECWCAALPAAFAVPAEGTGE
                     CYCPRCLAELIEARRQVPREARG"
     gene            complement(17999..18364)
                     /locus_tag="P5537_08030"
     CDS             complement(17999..18364)
                     /locus_tag="P5537_08030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004377455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="barstar family protein"
                     /protein_id="HRV78028.1"
                     /translation="MSQALQAPATPPLQPHRIDLAGCTDKAELLARIARTLRFPDWFG
                     HNWDALADCLCDLSWLPADAYRLEFVHADALRAAAPETVATLCEILDEAGDFWRAEGV
                     GFGHAFIPAPPEGPGGAPR"
     gene            complement(18376..18780)
                     /locus_tag="P5537_08035"
     CDS             complement(18376..18780)
                     /locus_tag="P5537_08035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004521 - endoribonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease domain-containing protein"
                     /protein_id="HRV78029.1"
                     /translation="MLRTVLLRLLLLLTLAAALPACSPGATPAAPQAAQGLLQPSHAG
                     LPPEAIETLALIQRGGPFPYRKDGTTFQNRERLLPARPRGYYREYTVPTPGSRDRGAR
                     RIVSGGDPPEVFYYTADHYRSFREIAPLRSLP"
     gene            complement(18787..20436)
                     /locus_tag="P5537_08040"
     CDS             complement(18787..20436)
                     /locus_tag="P5537_08040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004377450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV78030.1"
                     /translation="MLLPHGLQVLVVESQSSMRAQLRNMLASIGVDAPQFAVSASMAM
                     RRLRAQTYDLILSEYDLGEGQDGQHLLEDLRQHAIIPPETVFVMITGERNYERVISAC
                     ELIPNDYILKPLTAESLRVRLLRAFEKRDAFLPVWQLMKLGDPVGALAACREARDRHP
                     QYLVDFMRLQAELHAQIGQVDEAAALYREILAARPIPWASLGLARMLVVREAWVEAEH
                     LLTDLVARHPRFIEAHELLARVQEETGRPAEACETLQRATALSPYRLPRLRRLGELAL
                     QAGELDRAEHSLAEAVRRGGYSEFRDPEDHVRLVQAQLARERPDEALATLADLERNLV
                     RHPKGELCLAVGNALVEGHRNDAEGLRGAMVRALSSPERIRELSPGLRRDLLELCYDR
                     KLENEGRQLLADLMRTHGDDRSLASTRAALEARGFGGLSAEVEQQVQTEVKTLVGAGA
                     EKARAGDYDGAVAEMMNAARKMPGNPHVLFNAALALLRHIEHRGWNEAFAAQARSLIE
                     RTQRLAPTNPRLAAITEFRHELMKRYGIRPERAPIPRNRRA"
     gene            complement(20599..22398)
                     /gene="aspS"
                     /locus_tag="P5537_08045"
     CDS             complement(20599..22398)
                     /gene="aspS"
                     /locus_tag="P5537_08045"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004377448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HRV78031.1"
                     /translation="MRTHYCGKVTAADLDQIVTICGWVHRRRDHGGVIFIDLRDREGL
                     VQVVCDPDRADMFKTAESVRNEFVLKMSGKVRRRPAGTENANLTSGEIEILCHDIEVL
                     NAAATPPFQLDDENLSETVRLTNRVIDLRRPQMQKNLMLRYKTTMAFRRFLDGAGFID
                     VETPMLTKSTPEGARDYLVPSRVHPGQFFALPQSPQLFKQLLMVAGYDRYYQIVKCFR
                     DEDLRADRQPEFTQVDLETSFMNEHEITALVEEMIRFVFKEAMDVELPAPFPRMTYAE
                     AMRRYGSDKPDLRVTLELTDVTDAVQDVAFKVFSGPATSGGRVAAMRVPGGNALTRGE
                     IDEFTKFVGIYGAKGLAYIKVNDVTQPNEQGLQSPIVKNLHETALRTILERTGAQSGD
                     LIFFGADKTKVVNDAMGALRIKLGHEKGYVTGEAWRPLWVVDFPMFEYDEDDKRWTAC
                     HHPFTSPKDEHIDLLESNPGECLAKAYDLALNGWEIGGGSVRIHRADVQARVFEALNI
                     GPEEQQAKFGFLLDALKYGAPPHGGLAFGLDRIVTMMTGAESIRDVIAFPKTQRAQCL
                     LTDAPSGVDEKQLRELHIRLRQKVDTQVEVERG"
     gene            complement(22486..23112)
                     /locus_tag="P5537_08050"
     CDS             complement(22486..23112)
                     /locus_tag="P5537_08050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF502 domain-containing protein"
                     /protein_id="HRV78032.1"
                     /translation="MKKYFITGLLIWLPLAITYMVISWIVGTLDAILLWLPEEYQPSR
                     YLGVHIPGVGVIAGLLLVFFTGLVAANVIGQKLVKLWEALLARIPVVKSIYYSVKQVS
                     DTVFSSSGQAFRKALLVQYPREGVWTIAFLTGQPGGDAAEHLRGDYVSVYVPTTPNPT
                     SGFFLMMRRSEVVELDMSVDDALKYIISMGVVAPPMRRREPAPALPES"
     gene            complement(23195..23458)
                     /locus_tag="P5537_08055"
     CDS             complement(23195..23458)
                     /locus_tag="P5537_08055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HRV78033.1"
                     /translation="MPIYEYRCPSCGFQKEHLQKMSDEPLSVCPSCGAAGYAKLLSAA
                     GFQLKGSGWYATDFKGGAKSAAPAAESTPAPAAGGCGGGCACH"
     gene            complement(23616..24467)
                     /locus_tag="P5537_08060"
     CDS             complement(23616..24467)
                     /locus_tag="P5537_08060"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HRV78034.1"
                     /translation="MLGFLSDPIAFTTLAGLLGLFVGSFLNVVIHRLPRMMERDWHAQ
                     AAELRGEEPPAGERFNLATPRSRCPHCGHQITLLENIPLVSYLVLRGRCGHCGAGISK
                     RYPIVEAVSALLSAYAAWHFGFGAAALGALLFVWAMVALTFIDLDTQLLPDDITLPLL
                     WLGLAFNVGGTYTELPAAVIGAMAGYLALWSVFWLFKLATGKEGMGYGDFKLLAAIGA
                     WLGWQMLPLTILLSSLVGAVVGIVLIVAARHGRNVPIPFGPYLAAAGLIALFWGEGIT
                     ARYLGLL"
     gene            complement(24471..25700)
                     /locus_tag="P5537_08065"
     CDS             complement(24471..25700)
                     /locus_tag="P5537_08065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HRV78035.1"
                     /translation="MATASRAARATGPKEDLYIWEGKDKTGKVIRGEIRATGDAMVQA
                     MLRRQGIQVIKVRKQKMARGGRISEKDIALFTRQLATMMKSGVPLLQAFDIAMKGSAN
                     AALSRMLNDIRTDVETGSNLSQAFAKHPAHFDRLFCNLVAAGEQAGILDGLLDRIATY
                     KEKILAIKSKIKSALFYPTAVVVVAGLVISVMMLFVIPEFKSVFKSFGADLPAPTLLV
                     IAISDAFVAYWYLIFGAIIAAIVSIAWSYKRSTAMQIAVDRLVLRIPVVGAIIRKATV
                     ARWTRTLSTMFAAGVPLVEALDSVGGASGNHVYLVATRQIQGEVSTGTSLTVAMQNAD
                     VFPTMVVQMVSIGEESGQLDSMLSKVADFFEQEVDDAVAGLSQLLEPLIMVFLGTVIG
                     GLVVAMYLPIFKLGAIV"
     gene            complement(25716..>26660)
                     /locus_tag="P5537_08070"
     CDS             complement(25716..>26660)
                     /locus_tag="P5537_08070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase, T2SS/T4P/T4SS family"
                     /protein_id="HRV78036.1"
                     /translation="PQDGRMKLVLSKNKAIDFRVSTLPTLHGEKIVMRILDPSSAMLG
                     IDALGYDPDQREALLAAVERPYGMILVTGPTGSGKTVSLYTCLNLLNKPGVNISTAED
                     PAEINLAGINQVNVNEKAGLTFSAALRAFLRQDPDVIMVGEIRDLETAEIAIKAAQTG
                     HLVMSTLHTNDAPSTLERLKNMGVAPFNIASSVILITAQRLARRLCSCKKAVDIPLQA
                     LVEAGFEPEELDGSWEPMGPVGCERCKGSGYKGRVGIYQVMPISEEIARIIMTGGNSM
                     DIAAQARREGVLDLRQSGLRKVRQGITSLEEVLATTNE"
BASE COUNT         4027 a         8690 c         9839 g         4004 t
ORIGIN      
        1 gccgcggcta tcgcgcctgc cggcgctcct acatgaaccg tcgcgggctg gtggcacggc
       61 gccatgtagg agcggcggca gccgcgaatg gggctgcgtg gagggtgacg gggtcgcggg
      121 tgatcgccgc ggctatcgcg cctgccggcg ctcctacaga aaccaccggg gccccgggcc
      181 catgtaggag cggcggcagc cgcgaacggg gcgggtcaga cctcgccgga ctcgagctga
      241 cggcggatct cgagcagctt ctcgcggcgc gcggcggtgg tctcggggta gtgcaggtcg
      301 agcccggcga gggtgtcgac caggatctgc gacacgatca ggcgggcgtt cttcttgtcg
      361 tcggcgggca ccacgtacca cgggcagtcg ggcgtgctgg tggcgcgcag gcagtcggcg
      421 taggcggcca tgtacttgtc ccagtgcttg cgctgctcga tgtcgccctc gtcgaacttc
      481 cagttcttgt cctcctcgtc gatgcgcgcg atcaggcggt cgcgttgctc gtccttggac
      541 aggtgcagga agatcttgac gatgcgggtg ccgttgcggt gcaggtgggc ttcggcgtcg
      601 acgatggact ggaagcggtc gccccagaag tcgcgcgcgg cgagggtctc gtcgggcagc
      661 ttctggccgc gcaggatctc ggggagcacg cgcacgatga gcacctcctc gtagtacgag
      721 cggttgaaga tgccgatgcg gccgcgctcg ggcagcgcgc agtgggtgcg ccacatgaag
      781 tcgtggtcga gctcggtggc gctcgggtgc ttgaagctga acacctggca gccctgcggg
      841 ttgatgcccg acatgacgtg gcggatggcg ccgtccttgc cggccgcgtc catggcctgg
      901 aagatcacca gcagcgagta gcggtcgtgg gcgtagagca tctcctgcaa ctcggccatg
      961 cgagcggtgc ccgcgtccag gcgttcctgg tagtcgctct tcgagtcgta cagggcatgg
     1021 accctggtcg gccagtcggc gaggtcgatc ttcctgccgc cccggacgcg gaactcggcg
     1081 atgtcgatcg gtttgtgctt gctcatggtg tgctccctgg ggaaggttgc gggggggtag
     1141 ggaagaggcg gagaccttgt gtgcagaagg gggtcggggc cgcccctaaa gcaggaggac
     1201 ggtggccagc ccgaggaagg cgaagaagcc gaccacgtcg gtgaccgtgg tgagaatgac
     1261 gctgccggcg agcgcggggt cgatgcccat gcgttcgagg atgagcggga tcgccagccc
     1321 ggcgagcgcg gcgcacagca ggttgagcag gatcgcggcg gcgatcacgc cgccgatgcc
     1381 ccagtcgccg aaccacgcca cggcgagcgc cgccaccacc agcgcccaca gcaggccgtt
     1441 gatgatcgac acgccgacct cgcggttgag caggatgcgg atgttgccct tctgcacctg
     1501 cttgagtgcg aggccgcgga tgaccagggt cagcgtctgg ctgccggcga tgccgcccat
     1561 gctggcgacg atgggcatca gcaccgcgag cgcgacgatc tgctcgagcg tgccctggaa
     1621 ctggccgatc acccacgcgg cgaggaaggc ggtgagcagg ttgatgccca gccacaccgc
     1681 gcgccggcgc gagctcacca gcaccggggc gaacatgtcg gcctcgtcgt cgaggccggc
     1741 catctgcatc accgcgcggt cggagtcctc gcggatcagg tcgaccacgt cgtcggcggt
     1801 gatgcggccg acgaggcggc cggctgcatc gaccaccggc gcagtgagca gatcctgatc
     1861 ctggaacatg cgcgcaagct ccaggctccc ggtgtcgacc gggatcgcgg ccacgtcggt
     1921 acgcatgatg tcggccacgt gcgtgtcggg ctcggcggtg accaggtcgg acaggctcag
     1981 cacgccctgg tacgtacccc tgcggtccac caccatcagc acgtcggtgc gcgggggcag
     2041 cttgtcgagc aggcgcaggt agcgcagcac ggtgccgacc ttcacctcgg cgcgcacctc
     2101 gatggtgtcg gcgttcatca ggccgccggc ggactcttcc gggtaggaca gcatcgactc
     2161 gagctgctcc cggcgcacgc cgctggtggc atgcaccagg cggttgccga gatcgggcgg
     2221 cagggtctgg atgaggtcga cgaggtcgtc gagctcgagg tgctggacgg cagcgatgag
     2281 gtcctcgagg tcgagctcct gggcgagcgt ggtgctgatc tcgtcgtgaa ggaagctgag
     2341 cacgcggccg gcgcgctcgg tctcgaccat gctccaggcc tggctgcgct cggccggcgg
     2401 cagggcctcg agcaggccgg cgaccttggc cggatgcatg cggtgcagca gcttgccgac
     2461 gcgcttgagc ttgcccgcct cgagcgcctg gcgcacggcc tgcagttcgc tgctcgcgcc
     2521 ctccggctcg ccctccggtc tggcgggcgc ggcctcgccg tcctcgcgcg attcgcgcag
     2581 catggccggg cgcagctccg ggctgaggtg gccgagtaca cgctgttcca ggctgccgcc
     2641 gatctgctgc cacagcacga ggcgctgcct gggcgacaga tgctcgagca gggcggcggt
     2701 cttggccgga tgcaggcgct gcagcagctt gcgcacgcgc ttgttgcggc cttcgccgag
     2761 cgccttgacg atctgctcgc tcagcgtgag cgggcgcgtg tcggcgctcg cagccttgcc
     2821 gtccgcaggg cggtcgtcgg ttcgcatttc gtcgttcatg acaggacgga tacctgcggc
     2881 agcagcgcct cggcaccgat ccgcgcgagc gcctcgcggc cgcgcacggt gaggtcggac
     2941 acgaagcggt attgctggcg cggatcgacc gggtaggcgc ggaccgtgta gcgcgtgccc
     3001 caggtctcct ccgcgatcga gaccacgacc ggggcgtcga aatacaggaa ggggctggtc
     3061 agcgcgacgt cctcgagcac ctcgcgcgcg cggcgggcat cgtgctgcgg gtggacgagg
     3121 aagttcgccg cgcattgcag caccgggctg ccgttgttgg cgttgcgcac ggccgaggtc
     3181 cacagcttga ggtgcggcac gatgatggtg tcgtcgtcga ccgtcacgag gctgacggta
     3241 cgcatgccca catggaccac ctcgccgtaa tggccgtcga gctcgaccca gtcgccgggg
     3301 cggtagggtt gctcgaaggc cgacaccacg ccggcgatca ggctgctcac gtagtccttg
     3361 agcgcgaagc cgatcgccag cccggcggca ccgagcagcg ccaccatgtt gcgcagcgag
     3421 ggctcgatca cgatgggcag gatcaggcct gaggcgatga cgatcagcac caggcgcagc
     3481 aacggcaccg aggcgagcag gtagtggcgg gcgcggccgt gcaggcggtt ggcgatccac
     3541 ggcagggcgc gctgcgaggc gcgcaccagc agtacggcga cggcggcgat ggccgcgatc
     3601 tcgatccagg cgctgcggtc gaggctgttg aagagtccgg cgagcttggg gctgtcttcg
     3661 agcatggtca gaacgcgtcc gtcaggtagc tgcggctgcg caggaattcg cgcacggtga
     3721 ggtaggccag cggcggcacc tgccagcgcg cggcctcgcc gccgccatca cgcgcgacca
     3781 ggccgagcgc ctcgaggcgc agcagcagcg actgcaggcg aggttcgggc gtgggcagca
     3841 ggtgggcgag cagggcggtg ggcaggctcc ggtgaatcag cagggcgtgg aagatgaagg
     3901 catggtcgtc gcccgagtcg gccggcaggc cgggcggggc gatgtcctcg cccagccaga
     3961 ccacgtcctc gcccagggtc atcccccggc tcgcggtgtc ggcagccgag ggcgcggtgc
     4021 cggattcgcc gtcctgcgcg ggccgtgcct gcggggcgct gcgcaggcgc tcgcgccagt
     4081 agtgccaggc caggcccggg ttgccccgga cgtgggcggc gagctggcgc agttcggggg
     4141 cgatcgcggc gtcgcggtcc tcgccatcgc tgtccggctc gggcagcagc ggcttgccgc
     4201 tgcgtgcgct gcgaaattcc accgcatgca cgccgctgca gaaggggcgg atgaagtgct
     4261 cggcgagtgc gctgccgtcg aaaccctgca gcgtgagcgc gacgccggcg ggcaggggcc
     4321 agatgcgctg cacgtaggcg aaggcccagc tgtcgcagcc gatcagcccc gggccgaggc
     4381 ggcccgagaa ggcggcggcc agaaagctgc gcagcagcgt cagcccctgc gcgtggcgca
     4441 ggaagcagcg ctccagccgg ggcaataccc aggggcgggc gtcgcgatcg tccgtgggtg
     4501 gcgggggcag gctttcgagc cagcgcggcg tgtcggcgag cacgtcggcc tcgtcgggca
     4561 ggtcgaggat gcgggcgccg tggcgcgcgg cccagtgggc gaggatctgc tcgtgcgcgc
     4621 agtgcggcgg gcacacgagc acgcgcacgc gtgcgtgcga cgcgtcgggg ggccgtgcgg
     4681 attcgtcgcg caggaagctc gccagcgcct cggccgcggc cgaccagtcg agcgccgggg
     4741 cgaggtgctc gaggcggacg ttgggcaggc tgcgcagctc ggtctcggcg cgcgcatggg
     4801 cctggtccgg gtcctcgctg cgcagcagcc gggccagcgc gcgccagcgc cggcgcatgg
     4861 ccgcgggctg ggagtcggtc gggcggacgt gttcgtcgag cgtgacgatc cgccacgggc
     4921 tgggtggtgc gcggcgggga tggctggcgt ccgtcatggc ttgtgggcga gttctcggga
     4981 aggcatgggg gcgatcatcc gtgcaggggc cacacgagca gcagcatggg gatggcgacc
     5041 gcggccacca gcacttcgag cgggaggcca aggcgccagt agtcgccgaa gcgcaacccg
     5101 cccgggccga ggatcagggt gttgttctgg tggccgatcg gggtcaggaa ggcgcacgag
     5161 gcgccgatcg ccaccgccat caggaagggg tcggcgctcg cgccgagcgc gttggcggtg
     5221 ccgatggcga tcggacacat caccgcggcg gtggcggcgt tgttcatgac gtcggacagg
     5281 aacatggtga cgatgagcag cgtggcgagg gcgaccaccg cgttgccgcg cgcgacgtcc
     5341 tcgagcagca cgcgggcgac gaggctggcg gcgccgctcg cctccatggc accggcgacc
     5401 gggatcagcg ccgccagcag cacgatcacc ggccagtcga tgctctcgta caccgagcgc
     5461 agcgccacgg tgcgcagggc catcgaggcc agcacgccga gcgcgaaggc gatcgcggcc
     5521 ggtagcaggc cgagcgcggc ggcagcgacc gcggcggcca tgatcacccc cgccgtccac
     5581 gccttgcgcc ggtcggggat ccacagctcg cgctcggcga gcgggacgca gccatggtcg
     5641 gcagcgaact cgttgagcgc ctcgaccggc ccctgcatca gcagcagatc gccggccttg
     5701 agcttgagcg tgcgcagccg ggccttggcg cgcgtgccct cgcgcgacac cgcgagcagg
     5761 ttgagcccgt agcgcgtgcg cagcgcgagg tcccgcgccg agcggttgat caggctggcc
     5821 tcggggcgga cgaccagttc catcagcacg atctcgttgt cgggggaggg cttgtcgctg
     5881 tccctcgctg cttccggggg ggcttcctcg tcacggccgt ccgcctgctt ctttcccttc
     5941 ttcgccgacg ccggctgcac ggcgcgggcc tcgtcgccct ccgcatcggc ggtcgctgct
     6001 gctgatccag cctgctcatc ctcgttcgac gagccggcct cttccagctc gagcccgagc
     6061 ccggacagga cctcggggag cgcctcgacg tcggcctcga tgaccaggat gtcgccggcg
     6121 tgcaccttgc ggccagactg cggcgcggtc atgcgcacct cgttgcgcac gaggccgatg
     6181 acctgcgcgc cggcatcgtc gaggcgggcc tcgatctcgc gcaggaacat gccggcggcc
     6241 ttgctctccc ggcccacgcg cacctcggtg acgtaggcgc cggtctcgaa gccttcggtg
     6301 ctggccttct cgcgggccgg caccaggcgc cagcccagca gcacgatgaa gaggccaccg
     6361 gcgagcgcga ccgccaggcc gatgggggcg aagtcgaaca tgccgaaggc gcccgcgccc
     6421 tgctgcgcac ggaagccgga cacgatcagg ttgggcgggg tgccgatcag cgtggtcatg
     6481 ccgccgagga tggtgccgaa ggcgagcggc atgagcacgc gcccgggcgg caactcgagg
     6541 cgggcagcca gctgcatcgc caccggcatc agcagcgcca tggcgccgac gttgttcatg
     6601 aagcccgaca gcagcgcgcc catcgcgacc agtgcggcca ggctcgccgc cagcccggcg
     6661 ccggagggca gcaggcgccg gctcagcgca tccaccgcgc ccgaggtctg cagcgcacga
     6721 ctcagcacca gcacgcaggc cacggtgatc accgcgggat ggccgaagcc ggcgaaggcc
     6781 gcgtcgggcg ccaccagccc gcccaccacg caggccagca gtgcgcctgc ggccaccatg
     6841 tcgtggcgcc agcgtcccca caggaacatg cccatggtgg cggcgagaat ggcgaggacg
     6901 aacagcggat cctgggtcat cgggcggggg cgtcgagacg ggcgggagag gagcagcggg
     6961 aggggctgcg ggatgggcgg cgggacgggc gacatccgcc cccgtgcggg cggacccgcg
     7021 gcgcagggga aggcgccacg cgtcacgggt cccctggatc gtgcatgtgc gggcattctg
     7081 cgctgcgcca agcggcacgt gcaatccccg tggcacgccg cccgcacccg atgccgagat
     7141 catcgccacc cgccatgcac gctgccccca gccatcccga gtggatggaa ggcctctgcg
     7201 gacgcctcgc cgaggacgac gagggccgcg tctgcgaggc gatctccggg gcggaatgcc
     7261 gcgagtcgag cccgatgctg ccgcgcatgc ggatcggtgc ggtcctgccg gtctccggtc
     7321 tcgtcagcgc cgccgcgcgc gcagcagcgc cttctcgccc tcgatgatca ggaacaccag
     7381 cacgccgatg gccatcggcg gcccccaggc ctcgagcggc agcggcgtgg tgccgaacca
     7441 ggtgttcatc gccggcacgt agacgaagcc gagctgcagc aggccgagca ggccgaccga
     7501 gacgatcgcg cccgggttgg tgaacatgcg cgagagcgcg aggctggagg cggtgaggaa
     7561 gcggctgttg aagaggtacc aggcctgcgc caccaccagg gtgttgaccg ccatggtgcg
     7621 cgccgtcccg agctccatgc cctgcagcag cgaatattcg aacgaggcga tggtggcgcc
     7681 gccgatgagc agcgacacga aacccacgcg catcagcatc gtgccgtcca tgatcgagcc
     7741 accgggcttg cgcggcgggc gctgcatgac gccgggctcg gcaggctcga aggcgagtgc
     7801 gagcgccagc gtgaccgcca ccaccatgtt cacccacagg atctgcaccg gggtgagcgg
     7861 cagcgtgagc ccgaacacca ccgcggcgag catcaccagg ccctgcgcac cgttggtcgg
     7921 cagcgtgaac aggatggcct tgcgcaggtt gtcgtagatc gtgcggcctt cctcgaccgc
     7981 gcgctcgatg gtggagaagt tgtcgtcggc gagcacgatc tcggcggcct ccttggtggc
     8041 ctcggtgccc ttgatgccca tcgccacgcc gacgtcggcg cgcttgagcg cgggggcgtc
     8101 gttgacgccg tcgccggtca tcgccaccac ctcgccgcgc gcctgcaggg ccttgaccag
     8161 gcgcagcttg tgctcggggc tggtgcgggc gaagaggtcg cagtcgtggg cgattcgctg
     8221 cagctcctcg tcgctggcgg cctcgatctc ggcgccggtg atcaccttca gcgtgtcggc
     8281 cgcgcccagg cccatctcga tgccgatcgc gcgcgcggtg ccggcgtggt cgccggtgat
     8341 catcttcacg cggatgccgg cttcgtggca ggagcggatg gcctcgatcg cctccgggcg
     8401 cggcgggtcg atgatgccga tgaggccgag gaagaccatg tcctcctcga gatcctcgac
     8461 ggcgagcgcg tccttgctgg cgggcacgtc gcgcgcggcg gcggcgagca cgcgcaggcc
     8521 ctcgccgctg agcgcgtcga tgtgcgcttc ccagaaggcg cggtcgagcg cctcgagttc
     8581 gccttcggcg ccgagctcgt gccggcagcg ctcgagcagg cggtcgggcg cgcccttgag
     8641 caggatgcgg cgctggccgc cgggggcggt gttgagcgtg gccatgaact tgttggccga
     8701 ctcgaagggg atgctggcgt ggcgctcgtg ggcgccggcg tcgaagccgg ccttgtgcgc
     8761 gagggtgcgc agcgcgccct cggtgggctc gccggtgacc ttccactggc cgtcttcctc
     8821 ggcgacgtgg gtgtcgttgg cgaccgcgac gacctcgatc agcgcttgca ggtggccgtg
     8881 gcgggccagg ctggcgacct cgccttcgag ggtgatctcg ccctcggggc ggtagccggt
     8941 gccgctgacc tcgtagaagc cgccgcgggt gagcacgtgg cgcacggtca tctcgttctt
     9001 tgtcagcgtg ccggtcttgt ccgagcagat cacggtgacc gagccgagcg cctcgaccgc
     9061 ggtcagcttg cgcgtgatcg cgttgcgctg cgccatgcgc tgcacgccga gcgcgagcgt
     9121 gatggtgagg atggcgggca ggccctcggg gatggccgcg accgcgaagc cgatcgcggc
     9181 caggaagacc tcggccagcg gctgctcgtg caccgcgagg ccgacgccca gcatgagcgc
     9241 ggccaggccg acgatgacga tcgacaggat cttgctgaac cgcgccatct gccgggtgag
     9301 cggggtctgc agggtctgca cctcggcgat caggcggttg atgcggccga gctcggtgtc
     9361 ggggccggtg gcgacgacca cgccggtgcc gcgcccggcg gcgaccaggg tgccggagta
     9421 ggccatgccg aggcggtcgc ccacgccggc atcggcggcg accgcctcgg tggtcttgtc
     9481 ggcgggcacg gactcgccgg tgagcgcgga ctcctcgata cgcaggttgg tggcctcgat
     9541 caggcgcagg tcggccggca cgcgcgcgcc cgagcgcagg cgcacgacgt cgcccggcac
     9601 caggccgtcg gcgtccacgg cgctccattg gccgtcgcgg caggcgtccg cgcgcagcga
     9661 cagcatcttg cggatgccgg cgagcgcctc ctcggccttg ccctcctgga tgaagccgat
     9721 gatggcgttg atgaccacca cgccgaggat gacgccggtg tcgatccagt ggccgaggct
     9781 ggcggtgatc gccgcggcgc cgagcagaac gtagatcagc acgtcgttga agtgcttgaa
     9841 gaagcgcttc agcagcccgt cccggggcgg ctcgggcaga cggttggggc cgacctcggc
     9901 gaggcggcgc gcggcctcgt ccgcggacag gcccgccggg cagctgtcca gcgccgacag
     9961 gacctcgtcg gccgtgcggg cgtgggcgtg ttcgaggagg gagagcgggg cggttcgcgg
    10021 gctcatgtcc gtgctccggg ccggtgcgga tgcgctgcgt acaggatggc gcgcgcgggt
    10081 tcagaaggaa gaggctggtg caagcctgcg gcgcggatgg tgcgccgcat taaaacagac
    10141 cgcgccggcc gccgaagttc aaaaaaagac cccgcacagg gcagggtcct cgggtgtgca
    10201 ggcgcgcgcg ggggcggctc actcggtgtc gtagccgagc aggcgcttgt cgatgatgcg
    10261 ctgcgcaacc gcctcgggca cgtcggcctc ccactcgccg cggccgcggc gcaggccggc
    10321 cagcacctcg ccgatgtcga tgtgcaggtg ggtgtcgtcg tgcggctgca ccgccaccag
    10381 cttgtcgttc tccttgaggt gggcgagcag gtggcgcagg ttggcgggga cggccacgtt
    10441 gtcgagggtg accgtagccg aggcgtcggt gccgcgcggg cgcgacgggt acacatagac
    10501 gtgggtgttg tcggggaaga gcttgccgaa ggcctcgagg atgccgccct ccaggccctc
    10561 gtagtacttc tcgtcgaaca ggaaggcgaa gtcgcgcacc gacagcacga tgccgatcgg
    10621 cttctgcgtg tagcggcgca ggtaggcgcg caggcggaag aagcgcacgt agtccgagat
    10681 catcaccgtg tagccctgcg aggcgagcag gtcgatgcgg gcgaggaagt cggcgccgtc
    10741 cacgttgtcg ccgctgatca gcgagttcat ggtgatctcg gcgagcgaga cgatctcgcc
    10801 gtcgtcgacg gcggcgagct ggctgaactg gcgcacgccg gcgctcatca tgtccacatt
    10861 gaccagggtg accggcttga agctgccgcg catcaccatc accggcttgc ggtagaggag
    10921 ctcgcccggc accaccacct cgccctgcgg gttgaacacc accgcgcgcg tgagccagct
    10981 gcggatcagg tgcaggttca tcaggcggtt ctccacctcc tcgaagtagg ggccggagaa
    11041 gtggatgagg tcgacctcga tgcgctcgga gccgagcccg tcggcgaggc cctccaccac
    11101 ccactcgggc tggtcgtggt ggaagaaggc gccgtggatg aggttgacgc cgaggatgcc
    11161 gagcgcctcg gactgcagcg cgttgtcgtt gtcgagcatg cgcacgtgca tgaccacgtc
    11221 gctgggctcg gcgcccgggt gcagctgcag gcggatgccg acccagccgt ggcattcgtt
    11281 cttctgcttg aagctgcgcg cggtgacggt ggcggcgtag gcgaagaagg tggtgttcct
    11341 gggccgcacg tgggccagcc gcgcgacgac ctgggtgaac tccttgtcga gcatctgcag
    11401 caggcgggcg cggctgacgt agcggtcgac gtggccgtag atgtcgtcgc tcaccgccat
    11461 gtcgtaggcc gacatggtct tggcgatggt gccggcggcg gcgccgacgt ggaagaagcg
    11521 gcgtgccacc tcctgcccgg cgccgatctc gacgatggag ccgtacttgt acttgtccag
    11581 gttgatggcg agcgccttct ggtcggtggt cagcgtcgtg tcgcgtttgc gcattgcagg
    11641 tccttggtgg gcgggaggga cgggcgggag gggcgaaatt acttgagcgc gaagccgagc
    11701 gcgttgagcg cctcgatcag gcgatggcgg ccggacagcg tctcggggcc ggcgatgcgc
    11761 ttggacgagt gcacgctcca ggtgccgtgg acgttcatct tctgctccgc gtagaagcgc
    11821 tccatcgcgc ggtcgtaggc ggcgatgccg gcgtcctggg cttcgagcgc gtagcgctcg
    11881 tggtgcagca ccacggcctg cgggggacgc ggcttgatgt cggccggacg cgccggatcg
    11941 gggcggccga cgcacatgcc gaacaccgcg aacacgccgg gcggcaggcc gagcagctcg
    12001 gcgacctctt ccggacggtt gcgcatgccg ccgatgtaca ccatgcccag gccgagcgat
    12061 tcggccgcag cggcgccgtt ctgtgcggcg agcgcggcgt cgatgacgcc ggtgaggaac
    12121 atctcgaggt agtcgaggcc ctcggccgga cgcccgaggc cgtcggcgat gcggcgcagg
    12181 cgggcgaggt cggcgagcca cacgagctgc agcggcgcct cgcgcacgtg ggcctggtta
    12241 ccggcgagct ctgccagcct ggcgcggcgc tcggcgtcgc gcaccgcgac cacgctccac
    12301 acgttgaggt tggacgagct cgccgcagac tgcgcggcgg cgacgatcgc ggcgagttcg
    12361 gcatcggtga ccgggtcggg caggtaggcc cggaccgagc ggtggtcgag caggtgctcg
    12421 atgagcgggt tgagggcgat gtcggcagga acggattcct ggccgtagcg ggcttgcagg
    12481 cgggtagagg gctgggacat gtttgctcct tgcacggtcg gcggcgatac tcggccgggt
    12541 gccgcaagta tatcgatagt ggatgccgcg ctcggcggcc cgattcccgg cacgatgggc
    12601 gatttcctcc acctgccggc ccgtcgcggg ccgggcgagc cgatggccct cttttcaggc
    12661 gggcagggcg aggggtgggg caggttggtc gtgtccggcg ccgcgaggaa tccaccccct
    12721 ccataaacat aattttgatc aagaatggtg cgctgcgtta acgtcaacgt aaaatagcgg
    12781 gatcgggcgg gcaggcagcc gccccgagca ttccaacgac gtcctggaga ggagagaacc
    12841 catgagtgca gtcaatgaat ttctcgcggc gcgcgacttc ctgctgcagc accgcagcga
    12901 ctacgcgacc gcctacgccg gcttcaagtg gcccaggctc aaggagttca actgggcgct
    12961 ggactacttc gatgccatgg ccgagggcaa cgacaacccg gcgctgtgga tcatcgagga
    13021 agacggccgc gaatccaggc tgtccttcgc cgagatgtcg gcgcgctcga accgcgtcgc
    13081 caactggctg cgcaagcagg gcgtcaagcg cggcgagcgc atcctgatca tgctcggcaa
    13141 cgaagtgccg ctgtgggaga ccatgctcgc cgcgatcaag ctcggcgcgg tggtgatccc
    13201 cgcgaccacg ctgctgaccc ccgaagacct cgtcgaccgc gtcgagcgcg gccaggtcag
    13261 gcatgtggtg atcggcaagg cgcacaccga caagttcgag aacctgccgg gcaatttcgg
    13321 gcgcatcgcc gtgggtggcg cgcccgcggg ctggaaggcc ttcgaggagg ctgcggcaga
    13381 gtccgacgtc ttcaccccgg acggcgtgac ccgcgtcgac gacccgctgc tgctgtactt
    13441 cacctcgggc accacctcca agcccaagct ggtgctgcac acccaccagt cctatccggt
    13501 cggccacctg tcgacgatgt actggatcgg cctcaagccc aacgaccgtc acatgaacat
    13561 ctcctcgccg ggctgggcca agcacgcctg gagctgcttc ttcgcgccct ggaacgccgg
    13621 cgcctgcgtg ttcctgtaca actacaaccg cttcaacgcc gccgccctgc tcgacgtgct
    13681 ggtcaagtac gaggtcacca cgatgtgcgc gcccccgacg gtgtggcgca tgctgatcca
    13741 gcaggatctc gccgcggtca agaccaagct gcgcgagctg atcggtgccg gcgagccgct
    13801 caacccggag gtcatcgatc aggtgaagaa ggcctggggc atcaccatcc gcgacggttt
    13861 cggccagacc gagaccaccg cgcagatcgg caacaccccc gaccagccgc tcaagccggg
    13921 ctccatgggc cgcccgctgc ctggctacaa gatcgccctg ctcgacgccg acagcaagcc
    13981 ctcggtcgag ggcgaggttt cgctggtgat gggcgagcac cgcccggtgg gcctgatggt
    14041 gggttactcg ggtgatcccg ccaagaccgc cgaggtcatg cgcgacggcc actaccgcac
    14101 cggcgacgtc gccagcatcg acgaggacgg ctacatcacc tacgtcggcc gcgccgacga
    14161 cgtgttcaag gcctccgact accgcatcag ccccttcgag ctcgagagcg tgctcatcga
    14221 gcacccggcc gtggccgaag ccgcggtggt gccgagcccg gatccgctgc gcctggcggt
    14281 gcccaaggcc ttcgtgatcc tggtcgccgg ccaggagccg agccgcgagt tggcgaagga
    14341 catcttcgcc ttcacccgcg aacgcctggc cccgtacaag cgcatccgcc gcctgtcctt
    14401 cgccgacctg cccaagacca tctcgggcaa gatccgccgc gtcgagctgc gcaaggccga
    14461 agaggcgcgc ggcgaggctg cccgtggcga gctggagttc ttcgaagaag acttccccga
    14521 gctcaagggc tgaccggggg gttgatcgct gcggtgcggc gcggcgtcat tgccgcaccg
    14581 cagcggctgg catgctgcta caatgccggc cgtggcgggt ctcctcgcat tgcagcgcgg
    14641 tgaacctggt cagggccgga aggcagcagc cacagccgtt ccctgcaagt gccgggggtc
    14701 aggctcgcca ccccgaacac acgaagggcg ctcctcggag cgcccttcgt cctttgcgcg
    14761 tgcgcccagc gcctcacgcc tgacccttca cgccaccagc gtatccatca gcatcatcat
    14821 cacgaagccg accatcaggc caccggtggc gagcgtctcg tgaccgcggc ggtgcgactc
    14881 tgggatgatc tcgtggctga ccacgaagag catcgcgccg gccgcgccgg ccaggcccca
    14941 gggcaggatg gtcgccgaga ccgacaccat caccgaaccg gcgatcgccg cgaccggctc
    15001 gatcaggccc gacaccgccg cgacgccgaa ggcgagccag cgcccgtaac ccgccgccac
    15061 cagggcgatc gcgacgatca gtccctcggg cacgttctgc agcgagatgc cggcggcgac
    15121 cgcgtcgccc gagccggcgc ccgtgccctc gaggccggcg gccacgccga tcgccaggcc
    15181 ctccgggatg ttgtgcacgg cgatcgcgaa cacgaacagc cacaccgcgg cgccgctgcg
    15241 ccggccttcg gggaaatgcg tgtgcggcag ggcgcggtcc atcgcgagca ggccgccggc
    15301 gccgagcagc acgccgaacg cgaccagcag cgcggcgccg gtctccgtgc cggtctgtgc
    15361 gagcgcggct tcgaagccgg gcagcagcag cgagaacacg ctcgcggcga gcatgacgcc
    15421 ggcgccgaag ccgagcagca tgccctgcac gctggcgccg atccggcgca cgaccagaag
    15481 cggcaccgca ccgagtgcag tcgccgccgc agccatcgcg ccccctgcca ccgcacccga
    15541 caccgcaagc tcgaagccct cgacgctgcg cgcgagctgg gcgacgagca gggcaagtcc
    15601 ggtgaccgcg atcagccagc cgctgagcgc gcgcagggca ccggccgggc tggcaggctg
    15661 gaaatgcagg cgagcgacct tgtcgaccat gatggaaatc ctccgctgag ctcggcggca
    15721 tggccgcctt gtctgatgga gtcagtatcg gcgatgcgat tcaatagttc caattgaaca
    15781 tttcgacgat ttaaatagta attcggtatg tagagcgcgg tggcgggggg ctttgctgcg
    15841 gtgcacttcc ggttccgcgg gctggccact agaatccccc tgtccgatca aggagtctcc
    15901 cgatgaccca gcccgttcac cagcaagacg tcacgcccgc gcgcaaggcc gagatcctcg
    15961 ccgaggcgct gccctacatc aaacgcttct tcgacaagac catcgtcatc aagtacggcg
    16021 gcaacgcgat gaccgatccg cacctcaagg attgcttcgc gcgcgacgtg gtgctgctca
    16081 agctggtcgg cctcaacccg gtggtggtcc acgggggcgg cccgcagatc gagaacctgc
    16141 tcacccgcat gggcaagaag ggcgagttca tccagggcat gcgcgtgacc gacgccgaga
    16201 cgatggaagt ggtcgagatg gtgctcggcg gccaggtgaa caaggagatc gtcaacctga
    16261 tcaacaagca tggcggcaag gcggtgggcc ttaccggcaa ggacgccggc ttcatccgtg
    16321 ccaagaagct gctgatgcag aagcacggcg cgcccgaggg cgacctgatc gacgtcggtc
    16381 aggtggggga gatcaccggc atcgacccca gcctcatctc cttcctcgac cagggcgact
    16441 tcatccccgt gatcgcgccg atcggtgtgg gtgaggacgg cgagacgtac aacatcaacg
    16501 ccgacgtggt cgccggcaag ctcgccgaga tcctcaaggc cgaaaagctg gtgctgctca
    16561 ccaatacccc gggcgtgctc gacaaggccg gcaacctgct caccggtctg accccgcgcc
    16621 agatcgacga cctcgtcgcc gacggcaccc tgtcgggcgg catgctgccc aagatcggct
    16681 cggcgctgga cgcggcgcgc aacggcgtga agtcggtgca catcatcgac ggccgcgtgg
    16741 agcattgcct gctgctcgag atcctgaccg accacggcgt cggcacgatg atcaagagca
    16801 agtaggacgg cgcggtcgat cgagcgccgg caagcgcgca cgaggcgagc cagccgcctc
    16861 gatcatgtca ccccctgcac cgccgcctgc gcggctgccg gcgctcctac aggaggccga
    16921 ggaagcacga cggttcatgt aggagcgccg gcaggcgcga atgacggcag tgggggtttg
    16981 cgggcgcgcc aattgttttg ccgcacgatt cgcggctgcc gccgctccta caggnnnnnn
    17041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnngccgca cgattcgcgg ctgccgccgc
    17161 tcctacagga ggcccgggaa gcacgacggt tcatgtagga gcgccggcag gcgcgaatga
    17221 cggcgggtct ggcgcagggc gcttactcga tggtgagccg cctggcctgc acctcggcct
    17281 tcttgggcag gtgcaactcg agcacgccgt cgttgaactt cgcgctcgcg gcggcctcgt
    17341 cgatctcctg gccgagctgg aagctgcgcg acaccttgcc gaagtagcgc tcggtgcgca
    17401 gcaccttctc gccgtccttg atctccttct cctgcttgcg ctcggcgctg atcgacacca
    17461 ccggcccgtc gatatggacg tggatgtctt ccttcttcat accgggtagc tcggcatgca
    17521 cctcatagcc ctgcgcggtc tccttgacgt cgacccgcat ctgcggtgcg tcggtgccgg
    17581 gcgtggcaag ctgctggccg ccgaaatcta cggggcgcac gaaaaatccg cggaagaagt
    17641 cgtccagcgg gtcggtgcga cgggtgagag ggttgctcat gtcgtgtcct cctgtgtccg
    17701 ggttcttgcc gggggatccg gcttcaagac caatataggc acgcaggaag ggttttcaag
    17761 gggcgagcgt gcgtgcggcg tcgatcgcgg cgtcctcctc gtgacggcaa tcgaacgaac
    17821 ctgggaggcg caacgctgat gaacgaaacc accaatgtct gtccgcgctg cggcgcgagc
    17881 ttcacctgcg gcatgcgcgc gggtgaggcg gagtgctggt gcgcggcgct gccggccgcg
    17941 ttcgcggtgc cggctgaagg tacgggggaa tgctactgtc cgcgctgcct cgccgagctc
    18001 atcgaggcgc gccgccaggt ccctcgggag gcgcggggat gaaggcgtgg ccgaagccca
    18061 cgccttcggc acgccagaaa tccccggctt cgtcgaggat ctcgcacagc gtggccacgg
    18121 tctcgggcgc ggccgcgcgc agcgcatcgg cgtgcacgaa ctcgagccga taggcatcgg
    18181 cgggcagcca ggagaggtcg cacaggcagt cggcgagcgc gtcccagttg tggccgaacc
    18241 agtccgggaa gcgcagcgtg cgcgcgatgc gtgcgagcag ctcggccttg tcggtgcagc
    18301 cggcgaggtc gatgcgatgc ggctggagcg ggggcgtggc gggcgcttgc agggcttggc
    18361 tcatggacgg acggctcagg gcagcgagcg cagcggcgcg atctcgcgga agctgcggta
    18421 gtggtcggcg gtgtagtaga acacctcggg cggatcgccg ccgctgacga tgcggcgcgc
    18481 gccgcgatcg cgcgagccgg gcgtgggcac ggtgtactcg cggtaatagc cccgcggccg
    18541 tgccggcagc aggcgttcgc ggttctggaa ggtggtgccg tccttgcggt aggggaaggg
    18601 gccgccgcgc tggatgagcg ccagcgtctc gatcgcctcg ggcggcaggc cggcgtgcga
    18661 gggctgcagc agcccctgcg cggcttgcgg ggccgcgggc gtggcgccgg gtgagcaggc
    18721 gggcagggcc gcggcgagcg tgagcaggag cagcaggcgg agcaggacgg tacgcagcat
    18781 cggggttcag gcgcggcggt tgcgggggat cggggcgcgc tcggggcgga tgccgtagcg
    18841 cttcatgagc tcgtggcgga actcggtgat cgccgccagg cgcgggttgg tgggcgccag
    18901 gcgctgggtg cgctcgatca ggctgcgcgc ctgcgccgcg aaggcctcgt tccagccgcg
    18961 gtgctcgatg tggcgcagca aggcgagcgc ggcgttgaag agcacgtgcg ggttgcccgg
    19021 catcttgcgc gcggcgttca tcatctcggc gaccgcgccg tcgtagtcgc cggcgcgcgc
    19081 cttctcggcc ccggcgccga ccagggtctt cacctcggtc tgcacctgct gctcgacctc
    19141 ggcggagagc ccgccgaagc cgcgtgcctc gagcgcggcg cgcgtgctcg cgaggctgcg
    19201 gtcgtcgcca tgggtgcgca tcaggtcggc aagcagctgg cgaccctcgt tctccagctt
    19261 gcggtcgtag cacagctcga gcaggtcgcg gcgcagcccg ggggagagct cgcggatgcg
    19321 ctcggggctg gagagcgcgc gcaccatggc gccgcgcagg ccttcggcgt cgttgcggtg
    19381 gccctcgacc agggcgttgc cgacggcgag gcaaagttcg cccttggggt ggcggacgag
    19441 gttgcgctcg aggtcggcga gcgtggccag ggcttcgtcg gggcgctcgc gggcgagttg
    19501 ggcctgcacc aggcggacgt ggtcctcggg gtcgcggaat tcggagtagc cgccgcggcg
    19561 caccgcctcg gcaaggctgt gctcggcgcg gtcgagctcg ccggcctgca gggcgagctc
    19621 gccgagcctg cgcagccgcg gcaggcggta gggcgagagc gcggtggcgc gctgcagggt
    19681 ctcgcaggcc tcggcggggc ggccggtttc ttcctgcacg cgggcgagca gctcgtgtgc
    19741 ctcgatgaag cgcgggtgcc gggcgaccag gtcggtgagc aggtgttcgg cctcgaccca
    19801 ggcctcgcgc accaccagca tgcgcgccag tccgagcgag gcccagggga tcgggcgtgc
    19861 ggcgaggatc tcgcggtaca gggccgcggc ctcgtcgacc tggccgatct gggcgtgcag
    19921 ttcggcctgc aggcgcatga agtcgaccag gtactggggg tggcggtcgc gcgcctcgcg
    19981 gcaggcggcg agcgcgccaa ccggatcgcc gagcttcatg agctgccaca ccggcaggaa
    20041 ggcgtcgcgc ttctcgaacg cgcgcagcag gcgcacgcgc aggctctcgg cggtgagcgg
    20101 cttgaggatg tagtcgttgg ggatgagctc gcaggcgctg atcacgcgct cgtagttgcg
    20161 ctcgccggtg atcatcacga acaccgtttc gggcggaatg atggcgtgct ggcgcaggtc
    20221 ctcgagcagg tgctggccgt cctggccctc gccgaggtcg tattcggaca ggatgaggtc
    20281 gtaggtctgc gcgcgcaggc ggcgcatcgc catgctcgcc gataccgcga actgcggcgc
    20341 gtcgacgccg atcgaggcga gcatgttgcg cagctgcgcg cgcatgctcg actgggattc
    20401 gacgacgagg acctgcaggc cgtggggaag gagcatcgga tggcgtggcg gacgcacgcc
    20461 ggcggcgtgc catgtccgaa gattacggca ggcggcgcaa aggctgaagc ccccgcgacg
    20521 aagaaatgct gctcttcgtc gcgggggctt caggtgcgaa cggcctgcgg gagcgagcct
    20581 gccagcgcag tcgggcgctc agccgcgctc gacctcgacc tgcgtgtcaa ccttctggcg
    20641 caggcggatg tgcagctcgc gcagctgctt ctcgtccacg ccgctcggcg cgtcggtgag
    20701 caggcattgg gcgcgctggg tcttggggaa ggcgatgacg tcgcggatgg actcggcgcc
    20761 ggtcatcatg gtgacgatgc ggtcgagacc gaaggccagg ccgccgtgcg ggggcgcgcc
    20821 gtacttgagc gcgtcgagca ggaagccgaa cttggcctgc tgctcctcgg ggccgatgtt
    20881 gagcgcctcg aacacgcgcg cctgcacgtc ggcgcggtgg atacgcaccg agccgccgcc
    20941 gatctcccag ccgttgagcg cgaggtcgta ggccttggcg aggcactcgc ccgggttgga
    21001 ttcgagcagg tcgatgtgct cgtccttcgg gctggtgaag gggtggtggc aggcggtcca
    21061 gcgcttgtcg tcctcgtcgt actcgaacat cgggaagtcg accacccaca gcgggcgcca
    21121 ggcctcgccg gtcacgtagc ccttctcgtg gccgagcttg atgcgcagcg cgcccatggc
    21181 gtcgttgacc accttggtct tgtcggcgcc gaagaagatc aggtcgcccg actgcgcgcc
    21241 ggtgcgctcg aggatggtgc gcagcgcggt ctcgtggagg ttcttgacga tcggcgactg
    21301 caggccctgc tcgttgggct gggtcacgtc attgaccttg atgtaggcca ggcccttggc
    21361 gccgtagatg ccgacgaact tggtgaactc gtcgatctcg ccgcgggtga gggcgttgcc
    21421 gcccggcacg cgcatcgcgg cgacgcggcc gcccgaggtg gcggggccgc tgaacacctt
    21481 gaaggcgacg tcctgcacgg cgtcggtgac atcggtgagc tcgagggtga cgcgcaggtc
    21541 gggcttgtcc gagccgtagc ggcgcatcgc ctcggcgtag gtcatgcgcg ggaagggcgc
    21601 aggcagctcg acgtccatcg cttccttgaa cacgaagcgg atcatctctt ccaccagcgc
    21661 ggtgatctcg tgctcgttca tgaacgaggt ctcgaggtcg acctgggtga attcgggctg
    21721 gcggtcggcg cgcaggtcct cgtcgcggaa gcacttgacg atctggtagt agcggtcgta
    21781 gccggccacc atgagcagct gcttgaagag ctgcggcgac tgcggcaggg cgaagaactg
    21841 gcccggatgc acgcgcgagg gcaccaggta gtcgcgcgcg ccttcgggcg tgctcttggt
    21901 gagcatcggc gtctcgacgt cgatgaagcc ggcgccgtcg aggaagcggc ggaaggccat
    21961 cgtggtcttg tagcgcagca tcaggttctt ctgcatctgc gggcgacgca ggtcgatgac
    22021 gcggttggtc aggcgcacgg tctccgacag gttctcgtcg tcgagctgga agggcggcgt
    22081 ggcggcggcg ttgagcacct cgatgtcgtg gcagaggatc tcgatctcgc ccgaggtcag
    22141 gttggcgttc tcggtgccgg ccgggcggcg gcgcaccttg ccgctcatct tgagcacgaa
    22201 ctcgttgcgt accgactcgg cggtcttgaa catgtcggcg cggtcggggt cgcacaccac
    22261 ctgcaccagg ccctcgcggt cgcgcaggtc gatgaagatg acgccgccgt ggtcgcggcg
    22321 gcgatgcacc cagccgcaaa tggtgacgat ctggtcgagg tcggcggcgg tgactttgcc
    22381 gcagtagtga gttcgcatgt cgggttccgc aggttcgggg gcgcttgcgc ccggggattc
    22441 aggattcggc agggtgggga ggctggaaga tcggatgtgc tgggttcagg actcgggcag
    22501 cgcgggtgcc ggctcccgcc tgcgcatggg tggcgcgacg acgcccatcg agatgatgta
    22561 cttgagcgcg tcgtcgacac tcatgtcgag ctcgacgacc tcgctgcgcc gcatcatcag
    22621 gaagaagccc gaggtcgggt tgggcgtggt cggcacatac acgctgacgt agtcgccgcg
    22681 caggtgctcg gccgcgtcgc cgcccggctg gccggtgagg aaggcgatgg tccacacgcc
    22741 ctcgcgcggg tactgcacca gcagcgcctt gcggaaggcc tggccgctgc tggagaagac
    22801 ggtgtcggag acctgcttga cgctgtagta gatcgacttc accaccggga tgcgtgccag
    22861 cagcgcctcc caaagcttca cgagcttctg gccgatgacg ttggccgcga ccaggccggt
    22921 gaagaacacc agcagcaggc cggcgatcac gcccacgccg gggatgtgca cgccgaggta
    22981 gcggctcggc tggtactcct cggggagcca cagcaggatc gcgtcgagcg tgccgacgat
    23041 ccaggagatc accatgtagg tgatcgccag cgggagccag atcagcaggc cggtgatgaa
    23101 gtattttttc aagtgcagtt cctggccgcc acacgccgcg gctgccggca tccgccgcgc
    23161 cgcggccggc ctgccgcgag atggttcggt gcgctcagtg gcaggcgcag ccgccgccgc
    23221 agccaccggc tgcaggtgcg ggcgtggatt cggccgccgg ggcggcgctc ttggcgccac
    23281 ccttgaagtc ggtggcgtac cagcccgagc ccttgagctg gaagccggcc gccgaaagca
    23341 gcttggcgta gccggccgcg ccgcaggacg gacagacgga caggggctcg tcgctcattt
    23401 tctgcaggtg ttctttctgg aaaccacagc tcgggcaacg atattcgtag atgggcatga
    23461 cgtgctcccg aaaacaagtg cgcaagtcta acgcaacgca gcataaggaa aaagcgcgtc
    23521 cggaaccggc gcgcgcaggc ttcaggtgag ggcgggagag ggcggcttca agccccgcgc
    23581 tgcggaccgc gtgcgcgggc ttgcgcgtcg cgcgttcaga gcaggccgag gtagcgcgcg
    23641 gtgatgccct cgccccagaa cagcgcgatc aggccggcgg cggcgagata ggggccgaag
    23701 gggatcggca cgttgcggcc gtggcgggcg gcgacgatca gcacgatgcc gaccaccgca
    23761 cccaccagcg aggacagcag gatggtgagc ggcaacatct gccagcccag ccaggcgccg
    23821 atcgcggcca gcagcttgaa gtcgccatag cccatgcctt ccttgccggt ggcgagcttg
    23881 aacagccaga acacggacca cagcgcgaga tagcccgcca tcgcgccgat gaccgcggcg
    23941 gggagctcgg tgtaggtgcc gcccacgttg aaggcgaggc ccagccacag cagcggcagg
    24001 gtgatgtcgt caggcagcag ctgggtgtcg aggtcgatga aggtgagcgc gaccatcgcc
    24061 cacacgaaca gcagcgcccc cagcgcggcg gcgccgaagc cgaaatgcca ggcggcgtag
    24121 gccgacagca gcgcgctgac ggcctcgacg atcgggtagc gcttgctgat gccggcgccg
    24181 caatgcccgc agcgtccgcg cagcaccagg tagctgacca gcgggatgtt ctcgagaagc
    24241 gtgatctggt ggccgcagtg cgggcagcgc gagcgcggcg tggcgaggtt gaagcgctcg
    24301 ccggcggggg gctcctcgcc gcgcagctcg gcggcctggg cgtgccagtc gcgctccatc
    24361 atcctgggca ggcgatggat cacgacgttg aggaagctgc ccacgaacag gccgagcagg
    24421 ccggccaggg tggtgaaggc gatggggtcg gagaggaagc cgagcatgac tcagacgatc
    24481 gccccgagct tgaagatcgg caggtacatc gcgaccacca ggccgccgat gacggtgccg
    24541 aggaagacca tgatcagcgg ctcgagcagc tgcgacaggc cggcgacggc gtcgtccacc
    24601 tcctgctcga agaagtctgc gaccttgctc agcatcgagt cgagctggcc ggactcctca
    24661 ccgatcgaga ccatctgcac caccatggtg gggaacacgt cggcgttctg cattgccacc
    24721 gtcaggctgg tgccggtgct gacctcgccc tggatctggc gtgtcgccac cagataaacg
    24781 tggttgccgg atgcgccgcc caccgagtcg agcgcctcga ccagcggcac gccggcggcg
    24841 aacatggtcg acagcgtgcg cgtccagcgc gccaccgtcg ccttgcggat gatcgcgccg
    24901 accaccggga tgcgcagcac cagccggtcg accgcgatct gcatcgccgt cgagcgcttg
    24961 tagctccacg cgatcgagac gatggccgcg atgatcgcac cgaagatcag gtaccagtac
    25021 gccacgaagg catccgagat ggcgatcacc agcaaggtcg gcgcgggaag gtcggcgccg
    25081 aagctcttga acacgctctt gaactcgggg atcacgaaca gcatcatcac cgagatcacc
    25141 aggccggcga cgacgaccac cgcggtgggg tagaacagcg ccgacttgat cttgctcttg
    25201 atcgcgagga tcttttcctt gtacgtggcg atgcggtcga gcaggccgtc gaggatgccc
    25261 gcctgctcgc cggcggcgac caggttgcag aacaggcggt cgaaatgcgc ggggtgcttg
    25321 gcaaaggcct gcgacaggtt ggagccggtc tcgacgtcgg tgcggatgtc gttgagcatg
    25381 cgcgacaagg ccgcgttggc cgagcccttc atcgcgatgt cgaaggcctg cagcagcggc
    25441 acgccggact tcatcatcgt ggcgagctgg cgggtgaaca gcgcgatgtc cttctcggag
    25501 atgcggccgc cgcgcgccat cttctgcttg cgcaccttga tcacctggat gccctggcgt
    25561 cgcagcatgg cctgcaccat ggcgtcgccg gtggcgcgga tctcgccgcg gatgaccttg
    25621 ccggtcttgt ccttgccttc ccagatgtac aggtcctcct tgggaccggt ggcacgtgcc
    25681 gcgcggcttg cagtggccat gaaatcgaac gtcctttatt cgttggtcgt cgccagcact
    25741 tcttcgagcg aggtgatgcc ctggcgcacc ttgcgcaggc ccgactggcg caggtcgagc
    25801 acaccctcgc ggcgagcctg ggcagcgatg tccatggagt tgccgccggt catgatgatg
    25861 cgggcgatct cctcgctgat cggcatgacc tggtagatgc ccacccggcc cttgtagccg
    25921 ctgcccttgc agcgctcgca acccaccggg cccatcggct cccagctgcc gtcgagttcc
    25981 tcgggctcga atccggcctc gacgagcgcc tgcagtggaa tatccaccgc cttcttgcac
    26041 gagcatagcc ggcgcgcgag gcgctgggcc gtgatcagga tcaccgagga tgcgatattg
    26101 aacggcgcca cgcccatgtt cttgaggcgc tcgagcgtgg agggtgcgtc gttggtgtgc
    26161 agggtggaca tcaccagatg gccggtctgt gccgccttga tcgcgatctc ggcggtttcg
    26221 aggtcgcgga tctcacccac catgatcacg tccgggtcct ggcgcaggaa ggcgcgcagg
    26281 gcggcggaga aggtcaggcc ggccttctcg ttgacgttga cctggttgat gccggcgagg
    26341 ttgatctcgg ccgggtcctc ggcggtggag atgttcaccc ccggcttgtt gagcaggttg
    26401 aggcaggtgt acagggacac ggtcttgccc gagccggtgg ggccggtgac caggatcatg
    26461 ccgtaagggc gctcgaccgc ggcgagcagc gcctcgcgct ggtccggatc gtagccgagc
    26521 gcgtcgatgc cgagcatggc cgagctcggg tcgaggatgc gcatcacgat cttctcgccg
    26581 tgcagggtcg gcagcgtcga gacgcggaag tcgatcgcct tgttcttcga cagcacgagc
    26641 ttcatgcggc cgtcctgcgg
//
LOCUS       DAOTIN010000040        26221 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_2141_length_26221_cov_8.756707, whole genome shotgun sequence.
ACCESSION   DAOTIN010000040 DAOTIN010000000
VERSION     DAOTIN010000040.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 26221)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 26221)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26221
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2141_length_26221_cov_8.756707"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..672
                     /locus_tag="P5537_08075"
     CDS             <1..672
                     /locus_tag="P5537_08075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002930637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HRV78037.1"
                     /translation="RAMAVPMKRFERPLLGHLTRPEMIAVLGQPGTGWTSQRDHLLLS
                     LLYNTGARVSEIVGVRVVDVVLDGAACVHLHGKGRKDRSVPLWKTTAAAIRAWLNANP
                     HLRDSAALLPNRSGHPMTRCNVAQRLALAVDRASAEQPSLKTKRISPHTLRHTTAMHL
                     LQSGVPFNVIALWLGHESTNTTHRYVEANLEMKEKALARLEAPDIKLKRFRAGDELMR
                     FLQTL"
     gene            complement(963..1550)
                     /locus_tag="P5537_08080"
     CDS             complement(963..1550)
                     /locus_tag="P5537_08080"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78038.1"
                     /translation="MKLAAILLALSLALPTAVLAQHNHGADTPYAGMQERAIKSLSDA
                     DIKELRRGGGWGLALPAELNGMPGPAHLLELKDQIPLSQDQIEKVQALFDDMRNAAIP
                     AGERLIAAEAALEAAFSEGAVEETSLRRMLAEAESARTELRFIHLSQHYKTVPFLAPQ
                     QIERYNVLRGYADDPCAKVPEGHNPEMYRRHMGCK"
     gene            1999..2835
                     /locus_tag="P5537_08085"
     CDS             1999..2835
                     /locus_tag="P5537_08085"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78039.1"
                     /translation="MQSGANRDAARTSRQSHSDFINREKIVPARTNKNAAPVVSTPFS
                     RVLQSVASPNRAALDAKMTKEVIRIALALDPVRAEPLGARFRPPVKLDPDKLRIDTWV
                     RLDFDLDLDGKPLGDGTLASDAYGLSMSNPVGNGPAYVRATTFGTSTTNVVSIHPKGV
                     YPAFYAKEGAIDVVFDRPTDSVSVDAYPINTTQCPETLTFCPSRPYMEAYDAQGALLA
                     KALYPGNVPFSFDMGDGWQTIRIDRTSRDISRVRISCQQCGCTTPNKAVFDNLSYHFQ
                     LP"
     gene            complement(2925..3752)
                     /locus_tag="P5537_08090"
     CDS             complement(2925..3752)
                     /locus_tag="P5537_08090"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78040.1"
                     /translation="MRTRPLLSIAALALGCTTALASPAEGVIAPDIERGEREFEFAFG
                     TERNRDGKPTNGLELSFGAGVTDRWATELGVEFEREPGDDMKYDGLEWENRFGLIIDE
                     EAPVALSLLLGFERPRERAEGWSSTLGLLSETKIGRFLLNANLLLERSWDVRAEEDGD
                     DAEDEDGDEDGDEDADETHALGEDDDESGTVLGYQWQLLYRQSHSLYYGVQGMGEVGK
                     WNDWAPRDDQEHKLGPAIFGRLKTAGGQRLNYDVGLLFGVTDGTPDYTLRFKLEYEL"
     gene            3954..5342
                     /locus_tag="P5537_08095"
     CDS             3954..5342
                     /locus_tag="P5537_08095"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78041.1"
                     /translation="MDQAGSTSIGKRILGALGACLTAACASNAPYHTTSEDGGACRTD
                     PDSPACRSSAYQEFERFDLAFAEFSERGNAFDDARVEAVLAKIAAKARADGVVLIVFV
                     HGWKHNASEDDPNVLSFKDSLETMTGVLGSSFAGTALGSRRLVGVYVGWRGASIELPL
                     LKELTFWDRKAVAEELGSGGVTRLLLDLDRITAGEARNVMVVVGHSFGGAIVVRALSD
                     LITERVTNRADDERARVFADGVLVLNPAIEANQALPFVEAALQRPYARDQLPLFISIS
                     SDADAATHYAFPAGQTIGLATWRQADLQRSYYHDRRAPEQPLPLRERHLDATTAGNFA
                     PFLTHRLHADGEGDALRFTLDTCEAAGERCRPMGWTTLSGQPTIGPLPAHYPLYFIKT
                     DKSVMTDHNDIFNQKVRSFVFTVIDDVVRRALAGGVKAARGEGEPPLIASPERFAARM
                     NALWSQMGSGAR"
     gene            complement(5416..8196)
                     /gene="fdhF"
                     /locus_tag="P5537_08100"
     CDS             complement(5416..8196)
                     /gene="fdhF"
                     /locus_tag="P5537_08100"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002944271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009326 - formate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0008863 - formate dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_process: GO:0015942 - formate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="HRV78042.1"
                     /translation="MREATVAAFEITLDDVPVQAFPGETLWQVALRAGERIPHLCFKD
                     APGYRGDGNCRACMVEIEGERTLAASCIREARPGMVVRSASSARARQAREGVLELLLE
                     HQPARADSPDRSSHFWELVEQMRLPAAAATDAATDAPAPRPADRSHPAIHVALDACIT
                     CGLCVRACREVQVNDVIGLAHRGARATIVFDFDDPMGDSSCVACGECVQACPTGALMP
                     ASLIDADGRGDSACAERKVDSVCPYCGVGCQLTYHIRDERILFVEGRNGPANENRLCV
                     KGRFGFDYPNHHGRLTTPLIRRAGSPKGVDPAFDPASPLSHFRPASWDEALDFAAAGL
                     RRLLDAHGPGVLAGFGSAKCSNEEAWLFQKLVRTGFGSNNVDHCTRLCHASSVAALME
                     CIGSGAVTASFMQAAQADVVILTGCNPTVNHPVAATWFKQAAKRGTKLIVLDPRGLVL
                     GQHAHRMVRFTPGGDVALFNAMLHVIIGEGLCNRDFIAARTEGFEALAAHVAPMTPEA
                     MAPLCGVAPDEIRDIARLYANAGRAMIFWGMGISQHVHGTDNARCLIALALATGHVGR
                     PGTGLHPLRGQNNVQGASDAGLIPMVLPDYRPVGDAQYRAAFEELWATPLPAQPGLTV
                     VETMDAIAAGKVRGMYILGENPAMSDPDLHHTRAALARLEHLVVQDLFVTETAQFADV
                     ILPASAWPEKDGTVTNTNRQIQLGRAAVALPGEARPDWWIIQQLARRLGLDWDYAHPR
                     EVFAEMKRAMRSLDHIDWARLEREGAVTTPCAADDAQGKDVVFDDRFPTASGRARFRP
                     AVPLPPDEPVDAAWPTVLITGRQLEHWHTGAMTRRSAVLDALEPAAVATLAPGELARL
                     GLAPGVALTIETRRGRITLAARADPLMPEGMVFVPFCYVEAAANLLTNPALDPYGKIP
                     EFKYAACRLAPG"
     gene            complement(8494..10167)
                     /locus_tag="P5537_08105"
                     /pseudo
     CDS             complement(8494..10167)
                     /locus_tag="P5537_08105"
                     /inference="COORDINATES: protein motif:HMM:NF013662.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
     gene            complement(10201..10827)
                     /locus_tag="P5537_08110"
     CDS             complement(10201..10827)
                     /locus_tag="P5537_08110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF302 domain-containing protein"
                     /protein_id="HRV78043.1"
                     /translation="MNEATSAPEARPSTAPIPSRPGLRPARATARTPPRKRTTALCLP
                     RARFLLRTLRLAATCAAFAFASATSFAAPGEGIMVEHFPGVPFADLREALADAIADEG
                     LSAPVVSRFGAMLERTAPDLGHDPALYGDAEILSFCSAGLAARLVAEAREHIALCPLS
                     IAVYSLPHTPRDATLAWRPPTLDSPGGDAVRALMARIVVGAARLVGRR"
     gene            10857..11330
                     /locus_tag="P5537_08115"
     CDS             10857..11330
                     /locus_tag="P5537_08115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HRV78044.1"
                     /translation="MRPLVARLLTAWIIAQAPTSAHALDPEELDALVARPSIGLYKAY
                     AEFKMARYDSAREIWSALAQAGVAEAWFHLGILAEDGLGEPRDPAAALERYRRGGEAG
                     SSKAQYRLGLLHLEGRLVPADPVQARYWLAVAAANGDEEAARRLSALPGPMPAGQ"
     gene            complement(11496..12512)
                     /locus_tag="P5537_08120"
     CDS             complement(11496..12512)
                     /locus_tag="P5537_08120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinoprotein relay system zinc metallohydrolase
                     1"
                     /protein_id="HRV78045.1"
                     /translation="MSRSASSAPALHRRPAVRALRSLLAGLLFALCTLLAISPPVHAE
                     DFDYRLQPRELAPGAWVVVGLKEDFSFANGGNIVNTGFIVGSEGVIVIDTGSSKRYGE
                     QMLAAIRRVTPLPIVLVVNTHQHPDHFLGNQAFPRATLAALPETIAAIRSEGEGFNAN
                     MYRLNGDWMRDTEVVVPERALAAGRQRIGGRDVELRALGGHTVADLVVIDHDSGTVYA
                     ADLLFHDRTPTTPHADIARWLAALDTLEGLPARRWVPGHGEPATDLAPLRQTRDYLGW
                     LAQTIRAGAESGQDMTELFQTPIPPRFAGLALVNEEFRRSVVHLFPAAERAVLEAARA
                     KASR"
     gene            complement(12509..13372)
                     /locus_tag="P5537_08125"
     CDS             complement(12509..13372)
                     /locus_tag="P5537_08125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinoprotein dehydrogenase-associated SoxYZ-like
                     carrier"
                     /protein_id="HRV78046.1"
                     /translation="MTPSARPALAWIAAATTALGMLATAAAPAQAASSVPAASTPAPS
                     ASTAPTAAAGTQADPLDSPRWEDMRKSFFADATVVFDERVRVSGPAVAEDSLNVPVSV
                     DASGLPAVEELIVFADFNPIVKALRFEPGAAQPRLGFRIKLQQSSPVRAAARTADGVW
                     HVGGAWVTATGGGCTLPSVGSGSPEWQERLNEVNGKLWPRVDGGERLRMRIIHPMDTG
                     LAAGIPAFHIEDIVITDAEGRTLSRIQPLEPVSENPSFTLDLRAAAPGARLHVAGRDN
                     NGNRIDAWVTR"
     gene            13717..15525
                     /locus_tag="P5537_08130"
     CDS             13717..15525
                     /locus_tag="P5537_08130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol/ethanol family PQQ-dependent
                     dehydrogenase"
                     /protein_id="HRV78047.1"
                     /translation="MMKNDKRPRSLPAMLTALTVALAAAGMGATAQAASVTDEDILKD
                     AETTHQIVTNGLGTKGQRYSPLAKVNVDTVKDLVPVWAFSFGGEKQRGQQSQPLIHDG
                     KMFVTASYSRIYALDAKTGQKLWKYEHRLPEGIMPCCDVINRGAALYGDLVIFGTLDA
                     QIVALNRDTGKVVWREKIDDYKAGYSMTAAPQIVKGMVITGVSGGEFGVIGRVEARDA
                     KTGKKVWVRPVVEGHMGYKYDKDGKEIENGISGTTNATWPGDLWKTGGAATWQTAYYD
                     PDVNLIFMGTGNPAPWNSWLRPGDNLYSSSTVAVDPDTGKIVWHYQNTPHDGWDFDGV
                     NEFISFEYKDPKSGKLVKAGAKADRNGFFFVNDRTNGKLLGAYPFLTRIDWAKGYDLE
                     TGRPITNDDKRPPNPFAEGAAGEGGKGKPVFAAPSFLGGKNQMPMGYSPDTGLFYVPA
                     NEWGMDIWNEPVSYKRGAAYLGAGFTIKPLYEDYIGAMRAIDPVTGKIVWEVKNNAPL
                     WGGVLSTGGNLVFYGTPEGYLKAVNAKTGEEAWKFQTGSGVIAPPVTWEVDGEQYVAV
                     VSGWGGAVPLWGGDVAKRVNFLEQGGTVWVFKLHKS"
     gene            15693..16550
                     /locus_tag="P5537_08135"
     CDS             15693..16550
                     /locus_tag="P5537_08135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cache domain-containing protein"
                     /protein_id="HRV78048.1"
                     /translation="MRQIQLSSFATAVVLAVGVGTAAHAADRATPREARTMFEQAVRY
                     MEENGAERAFAAFNDRQGNFVRKDLYVFAIDDKGVYHASGAAPEALLGLKVLDTTDAA
                     GNPLFREMIDATRVTQEATVRYVWLNRATNKVEPKVSYVRKLGQYVVGVGYSAPRASA
                     DDARAMLERAVAVARSEGGAQAAARFNDRRGEFVKDDLYVFMVNMESGRFEAMGMNPA
                     LSDTDALGLRDAAGNALVAEMIARLQKADEATVDYVWRNPVTNAVENKRSYVRKVGTS
                     LVGVGHYLE"
     assembly_gap    16931..17030
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(17246..18091)
                     /locus_tag="P5537_08140"
     CDS             complement(17246..18091)
                     /locus_tag="P5537_08140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HRV78049.1"
                     /translation="MKTDRRRFLLTAGALAVLAASPARAAAAELELQQPGTLRVAVYA
                     NFAPWSSAGKGIETALGRALAERLGLQPQVVEFPADENMNDDLRNMVWRGHYLGHKPG
                     DVMLHVPVDPRFAAANKQVKIFGPYHLETIALARLPERVPAPGGSADASFGVFEQERI
                     GAELDSHASDFLRHILGGRLQPNVTHFRSVGEAVAAMKRGEVAAVMASRSELEAALGG
                     DAAIALDTLSMPELRVNSWPLGMAVKAEHGGLEQALSGAIAELQRSGELGRIFAAHGV
                     KQRTP"
     gene            complement(18081..18530)
                     /gene="pedF"
                     /locus_tag="P5537_08145"
     CDS             complement(18081..18530)
                     /gene="pedF"
                     /locus_tag="P5537_08145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-550 PedF"
                     /protein_id="HRV78050.1"
                     /translation="MNTRTIKENLRKRLAITATGLALATAGAFAHAHGDVTPQAVDTS
                     SLKQLGETWVTANPYRGNKDAIRIGDSAFNQNCARCHGLGAVSGGIAPDLRLLDINDD
                     DTDEFFIGKVRNGVTRNGAVYMPPFEGMLTQEAMWAIRAWLETVHEN"
     assembly_gap    18602..18701
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <18702..20543
                     /locus_tag="P5537_08150"
     CDS             <18702..20543
                     /locus_tag="P5537_08150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HRV78051.1"
                     /translation="VFEQIRASGSLVILSDPQGMILHSLGDAEFVDRASRVALQPGAC
                     WSEAARGTNAIGTAIATAAPTVVLGGEHYLDRNGFLSCTAAPIRDPRGALAGVLDVSC
                     EQRMHQRHSLGLVRLSVQLIEKRLFEAEFANHILVAFHERPEYVGSLQEGLVAVTPEG
                     HLAGANSIAREWIGRRVECGGGASFAELFRQGLGKVVDRAMSSSDALIRLGLRDGTEI
                     HVQLRSLRPRFTAFGASQAGEGGRSLAAEPMPAAVGCAPPAAPVKAGPVKAAEGPITL
                     ADLATGDVGIGRAVDRARRILGKDIPLLIQGESGVGKELFAQAFHNSGPRADRPFVAL
                     NCAAVPETLIESELFGYVGGAFTGARKEGAIGKIQQAHGGTLFLDEIGDMPLGMQARL
                     LRVLQERCVTPVGSVKSIPVDISLVCATHRVLRDAVARGEFREDLYYRVNSLTVTLPA
                     LRERSDIRCIVERILARECREAGLQGVWIGDEVMRFVERHGWPGNVRQLQNVIRVAVA
                     LLDEGEREIRPEHLPEDLFLADPVDGAKAPPVAAAAPVATAASAAAPLVADALASHGA
                     KRLDQLEIELIERVMREVGGNLSAAARTLGVSRNRLYRKLGRAGGTS"
     gene            20674..21153
                     /locus_tag="P5537_08155"
     CDS             20674..21153
                     /locus_tag="P5537_08155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HRV78052.1"
                     /translation="MWKALHIDPAKCTGCLQCEMACSYEHTGVINPSKSRIKVFNFEH
                     EGRKVPYTCTQCTEAWCLNSCPVDAIRIDLTTGAKMVFEDTCVGCKVCTIACPFGTIN
                     YNQDTGKVQKCDLCEGNPACASACPTGAITYVDADWTGIDKMRAWAAKANTPASAAA"
     gene            21166..23013
                     /locus_tag="P5537_08160"
     CDS             21166..23013
                     /locus_tag="P5537_08160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde ferredoxin oxidoreductase family
                     protein"
                     /protein_id="HRV78053.1"
                     /translation="MGWNRKVLRVNLTAGTCTEEPLNMQWADEYLGSRGLATKYLVSE
                     IDPKVDPLSSDNKMIMATGPLTGTMASTGGRYTVITKGPLTGAIACSNSGGFFGAEMK
                     FAGWDMVIFEGRSAKPVWLYIENDKAELRDASGLWGKSCWETEEKIKEELQDPLVRIS
                     SIGVAGENQVLYACIVNDLHRAAGRSGVGAVMGSKNLKAVAIRGTKGVSGIKDFGAFL
                     KATNDAKKVLADNAVTGQGLPKYGTQVLMNVINEIGALPTRNHRDVQFEDASKISAEA
                     MHEKRESDGKTHLVTNAACFGCTIACGRISEIDKTHFTVKNSPKYWGASGGLEYEAAW
                     ALGAANGVGDLEALQYANLICNEQGMDPISFGATVGAAMELYELGILTDEKIGMAAPF
                     GSAQALAKMVEMTAVGEGFGKELGLGSKRLCEKYGRPELSMSVKGQEFPAYDSRGIQG
                     MGLAYATSNRGACHLRGYTVASEVLGIPVKTDPLATEGKPELVKAFQDATAVFDSAGI
                     CVFTSFAWTLADVQPQVAAACEGDWSMEKLNEVGERIWNMERMFNNAAGFTAKDDNLP
                     PRLTQEAAKTGPAKGLVNQLDKMLPHYYEVRGWTPAGEPTAETRARLGL"
     assembly_gap    23086..23185
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            23328..24617
                     /locus_tag="P5537_08165"
     CDS             23328..24617
                     /locus_tag="P5537_08165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HRV78054.1"
                     /translation="MKHLILGNGPAGVVAAETLRKVAPADDILMVGFEDAPPYSRMAI
                     PYLLEGNIDESGTYLRKDAGHFERLRIRQLRGRAVALDTDKRKVLFDDGHFEHYDRLL
                     IATGSHPVRPPIPGVDLPSVHTCWTLSDARAIAAHAKPGARVLQLGAGFIGCIIMEAL
                     AKRGVQLTVVEMGDRMVPRMMTPKAGGMIKRWVEDKGIRVLTSAGVQRIDRGGDVDSD
                     APLVVSLSTGDRLDCDLVIVAAGVAPNVGFLDETPVHVAKGVLVNDHMETSVPGIFAA
                     GDVAEAPDLFTGAHLVSAIQPNAADQARIAATNMARDLVYESRLNGVLAINVLDTLGL
                     ISSSFGQWWGEKPEAGGSGVEMVDEARYRYLSLQFKDDVLVGATSIGLTQHVGALRGL
                     IHGQVRLGDWKDRLLANPLAFVDAYVARSQQPMALAR"
     gene            24640..24897
                     /locus_tag="P5537_08170"
     CDS             24640..24897
                     /locus_tag="P5537_08170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoaD/ThiS family protein"
                     /protein_id="HRV78055.1"
                     /translation="MTIRIAFKLFASLSDYLPSGHRGNRLELEVDEGTTVAEMIRRYN
                     VPERSAHLVLVNGHFVPPSERPRKRLAEGDELAIWPPIAGG"
     gene            24902..25210
                     /locus_tag="P5537_08175"
     CDS             24902..25210
                     /locus_tag="P5537_08175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78056.1"
                     /translation="MAFIAGPVPESFERRVTATPQEFARDLRQAWPAVVAEAGGLRFS
                     LHEGVQALVIAIEPAGVRRLGLFELPQLDVRFRFGPGEEPARRALLARLDRGMQKGGG
                     "
     gene            25271..25558
                     /locus_tag="P5537_08180"
     CDS             25271..25558
                     /locus_tag="P5537_08180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1330 domain-containing protein"
                     /protein_id="HRV78057.1"
                     /translation="MSHGYVVGHITVKDADKWAEYRGKVPDTLAPWGAELLFRGHRVA
                     SFSGDSPHADIVVIRFPSAAAASGWFASPAYQALIPLREQAAEVLLLSYED"
     gene            25656..>26221
                     /locus_tag="P5537_08185"
     CDS             25656..>26221
                     /locus_tag="P5537_08185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV78058.1"
                     /translation="MSAFAATFSDALSLLAHFDHTVLEIVALSLQVSGAAVVLGTLIG
                     LPLGACIAVGRFPGKTALSVLINGMMGLPSVVVGVVVYLILSRSGPFGALGMLYSPAA
                     MVVAQTLLVVPLMAAITRQVVEDVWARYAEELQVMRFSWWDSVTTLLHDCRHSLVVAV
                     LAGLGRAMSEVGAVMIVGGNIDGATRVMT"
BASE COUNT         3903 a         8548 c         9533 g         3937 t
ORIGIN      
        1 cgcgcgatgg ccgtgccgat gaaacgcttc gagcggccgc tgctgggtca cctgacgcgc
       61 ccggagatga ttgccgtgct gggacagcct ggtacgggat ggacttcgca gcgcgaccat
      121 ctgctgctga gcctgctgta caacaccggc gcgcgcgtct cggagatcgt cggcgtgcgc
      181 gtcgtcgacg tggtgctgga tggcgcggcc tgcgtccacc tgcatggcaa gggtcgcaag
      241 gatcgctcgg tcccgctgtg gaagaccact gcggcggcca tccgcgcgtg gctaaacgcc
      301 aacccgcacc tgcgtgattc ggcggcattg ctgcccaatc gatccgggca tccgatgacc
      361 cgctgcaacg tggcgcagcg actggcgctg gcggtggaca gggccagcgc agaacagccg
      421 agcctgaaga ccaagcgcat ctcgccgcat accctgaggc acacgaccgc catgcatctc
      481 ctgcaaagcg gcgtgccgtt caacgtgatc gcactgtggc tcggccacga gagtacgaac
      541 acgacgcacc gctacgtcga ggccaacctg gagatgaagg agaaggcact tgcccggctc
      601 gaagcacctg acatcaagct caagcgcttc cgtgccggcg atgaactgat gaggttcttg
      661 cagaccctgt aactatgcag agcacaccac gccccagtgc ggccgtcgac cgagcgaaca
      721 gccatgctgg ggggtgcccc tacgcatagt tgagagctat gcataggggt cggatcgaga
      781 cagccaaaat tgattcgccg cgctcacgta cagcagcttt ggaggctatt atcagaccga
      841 cctaagccga cgttcgctct gataacagcc tattgcgctg agtgcctgct tgagtatcaa
      901 ggcttccccc tcaggatcca ctgacgtaga gatcgcaagc tttaaagagg gccaaccatt
      961 catcatttac agcccatgtg tcgccgatac atctcggggt tgtgaccttc cggaactttc
     1021 gcgcacgggt cgtcggcata accacgcagc acgttgtagc gctcgatctg ctggggcgcc
     1081 aggaacggca ccgtcttgta atgctgggag agatggatga agcggagttc ggttcttgcc
     1141 gactccgcct cggcgagcat gcggcgcaat gaggtttcct ctacagcacc ttccgaaaat
     1201 gccgcctcga gagcagcttc tgcagcaatg agtcgctcac cagcgggtat tgccgcgttg
     1261 cgcatgtcgt cgaagagtgc ttggaccttt tcgatctgat cctgggagag cggaatctga
     1321 tctttcagct cgagcagatg tgccggcccc ggcatgccat tgagttcggc aggtaatgca
     1381 agaccccacc cccctccgcg ccggagttcc ttgatgtcag cgtccgacag cgacttgatg
     1441 gcgcgttcct gcatgccggc ataaggtgta tcggctccgt ggttatgctg cgccagaacc
     1501 gccgttggca aggcgaggct cagtgcaagc agaatggcgg ccagtttcac gttcatctcc
     1561 ttatggtggc gtgttggaat tctgcagatg gaggacggcc gaagcatcag aggctgccac
     1621 ccttgaagag tttcctgccg cgccgaggat tgggggcaag gtggccgtcg tcgcgtgcgc
     1681 cagcagtggg atcgggagaa cgatcgccga gcacgatgcg gaagaggggc ccgggtggtg
     1741 tctttcgcgg acagcaccgt ggaagccctc cataccaagt tttcggtcaa tctcttctac
     1801 gcggcggaga tcgtgcgttt cctcgtcccc cgcatctgca aggggctcga ttcggttcgt
     1861 caccaacttc ccgacccagt tgggcccctg cggccaggag atcgtcgtgg atggcggcta
     1921 cacgatcggg tgagcttcgt cgcgccttcc cggccgcggc gggccggctg gacaaggcgc
     1981 tcatccggca taaaatgaat gcaaagcggt gccaatcgag atgccgccag gacgtcccga
     2041 cagagccatt cggacttcat caatcgggag aagatcgtgc ctgccagaac caacaaaaat
     2101 gccgctccgg tcgtttcgac cccgttcagc cgggtgctcc agtcggtcgc ttcgccgaac
     2161 cgtgccgcgc tcgatgcgaa gatgacgaag gaggtcattc gcatcgcgct cgcgctggat
     2221 ccggtccggg ccgaaccgct cggtgcccgc ttcaggccac ccgtcaagct ggatcccgac
     2281 aagctgcgga tcgacacctg ggtgcgcctg gatttcgacc tggacctcga cggcaagcca
     2341 ttgggcgatg gcaccctggc cagcgatgcc tacgggctgt cgatgagcaa tccggtcggc
     2401 aatggcccgg catacgtgcg tgccacgact ttcgggacga gcaccaccaa tgtggtttcg
     2461 atccacccga aaggagttta tccggcgttc tacgcgaagg agggcgcgat cgatgtggtc
     2521 ttcgatcgtc cgaccgacag cgtgtcggtg gatgcctatc cgatcaacac cactcaatgc
     2581 cccgagaccc tgaccttttg cccgtcgcga ccgtacatgg aggcctatga cgcacaaggc
     2641 gcgctgctgg ccaaggcgct ctatccgggg aacgtgccgt tctccttcga catgggggac
     2701 ggctggcaga cgatccgcat cgaccgcaca agccgtgaca tctcccgggt ccggatttca
     2761 tgccagcagt gcggttgtac gacgccgaac aaggccgtct tcgacaacct gagctatcac
     2821 ttccaattgc cgtgagtgat tggggcgccg ggctcgccgg ggccgtggcg ccccgcgagc
     2881 tgaggaactg tacggtggtg gtggcgccgg cgccaccgtt cattttagag ctcgtattcc
     2941 agcttgaagc gcagggtgta gtcgggcgtg ccgtcggtga cgccgaagag caggccgacg
     3001 tcgtagttca ggcgctgtcc gccggcggtc ttcaggcggc cgaagatcgc tggccctagc
     3061 ttgtgttcct ggtcgtcgcg cggggcccag tcgttccact tgcccacctc gcccatgccc
     3121 tgcacgccgt agtagaggct gtgggattgg cggtagagca attgccactg gtagccgagg
     3181 acggtgccgg actcgtcatc gtcctcgccg agcgcgtgcg tttcgtccgc gtcctcgtcg
     3241 ccatcctcgt cgccatcctc gtcctcggcg tcgtcaccgt cttcttcggc gcgcacgtcc
     3301 cagctgcgct cgagcagcag gttggcgttg agcaggaagc gcccgatctt cgtctcggac
     3361 agcagcccca gggtggatga ccagccttcc gcgcgctcgc gcgggcgctc gaagccgagc
     3421 agcaggctga gtgcgaccgg ggcctcctcg tcgatgatca ggccgaagcg attctcccac
     3481 tcgaggccgt cgtacttcat gtcatcgccg ggctcgcgtt cgaactcgac gccgagctcg
     3541 gtcgcccagc gatccgtcac acccgctcca aacgagagct ccagaccgtt cgtgggcttg
     3601 ccgtccctgt tccgttccgt accgaatgcg aactcgaatt cgcgttcgcc ccgctcgatg
     3661 tcgggggcga tcacgccctc ggcaggcgaa gccagtgccg tcgtgcagcc cagcgcgagc
     3721 gcggcgatgc tcagaagtgg tcttgtcctc atcttgtctc cctggttcct cggtggaaat
     3781 gaacgtgctc cacagcaatc gccatgccac ttcgagctca cgctgcaggg ggcggtgagt
     3841 gtgcccggca ctgcctggac aggcgtgtga ccggttccta agctgaaaga gaggggagat
     3901 cgacaaggcc gaaccgacgg gctggtcgtc ggccgcaaga acgggaggca gtcatggacc
     3961 aggcgggcag cacctcgatc ggcaagcgaa ttctcggcgc gctgggcgcg tgcctgacgg
     4021 ccgcgtgtgc gtcgaacgcg ccctatcaca cgacatcgga ggacggcggg gcgtgcagga
     4081 ccgacccaga ttcgccggcg tgtcgcagca gcgcctacca ggagttcgag cgcttcgacc
     4141 tcgccttcgc cgagttcagc gagcgcggca acgccttcga cgacgcaagg gtcgaggccg
     4201 tgctggcgaa gatcgcggcc aaggcgcgtg cggacggcgt ggtgctgatc gtgttcgtgc
     4261 acggatggaa gcacaacgcc agcgaggacg atccgaacgt gctcagcttc aaggattcgc
     4321 tggagacgat gacgggggtg ctcggcagtt ccttcgcggg gacggcgctg ggttcgcgcc
     4381 gcctcgtcgg cgtctatgtc ggctggcgtg gcgccagcat cgagctgccc ttgttgaagg
     4441 agctgacctt ctgggatcgc aaggcggtcg cggaggagct cgggagcggc ggggtcacgc
     4501 gcctgctgct cgacctcgac cggatcacgg ccggcgaggc gcgcaacgtg atggtggtgg
     4561 tcggccacag cttcgggggc gcgatcgtgg tgcgtgcgct ctccgacctg atcaccgagc
     4621 gtgtgaccaa ccgcgcggac gacgagcgcg cgcgcgtctt cgcggatgga gtgctggtgc
     4681 tgaacccggc gatcgaggcc aaccaggccc tgccgttcgt ggaggcggcg ctgcagcggc
     4741 cgtacgcgcg ggaccagctg ccgctgttca tctcgatcag ctcggacgcg gacgcagcca
     4801 cgcattacgc cttcccggcg ggccagacga tcgggttggc gacgtggcgg caggccgacc
     4861 ttcagcgttc ctactaccac gaccgcaggg cgccggagca gccgctgccc ctgcgcgagc
     4921 gccatctcga cgccaccacg gcgggcaact tcgcgccctt cctcacccat cgcctgcacg
     4981 cggatggaga gggcgacgcc ttgcgcttca cgctcgacac ctgcgaggcc gcgggcgagc
     5041 gatgccggcc gatgggatgg accacgctgt cgggccagcc tacgattggt ccactgccgg
     5101 cgcactaccc gctgtatttc atcaagaccg acaagtcggt gatgacggac cacaacgaca
     5161 tcttcaacca gaaggtgcgc agcttcgtgt tcaccgtgat cgacgatgtc gtgcgccgcg
     5221 ccctcgcagg cggcgtgaag gccgcgagag gcgagggcga gccgccgctg atcgcctcgc
     5281 ccgagcgctt cgcggcgcgg atgaacgccc tgtggagcca gatgggatca ggggcccgat
     5341 agcccctccg ccgcgccccg gatttcgtag gagcgacgca agtcgcgatc ggcggcgcgg
     5401 gcggaacggg tgtgctcacc cgggggcgag ccggcaggcc gcgtacttga actccggaat
     5461 ctttccgtag gggtcgagcg ccgggttggt gagcaggttc gccgccgcct ccacgtagca
     5521 gaagggcacg aagaccatgc cctcgggcat cagcgggtcg gcgcgcgcgg cgagcgtgat
     5581 gcggccgcgg cgggtctcga tcgtcagcgc gacgccgggg gcgaggccga ggcgggcgag
     5641 ctcgccgggg gccagcgtgg cgacggcggc cggctcgagc gcgtcgagca ccgcgctgcg
     5701 ccgggtcatc gcgccggtgt gccagtgctc gagctggcgg ccggtgatca gcaccgtggg
     5761 ccaggcggcg tcgaccggtt cgtcgggcgg cagcggcacg gcggggcgga agcgcgcgcg
     5821 tccgctcgcg gtggggaagc ggtcgtcgaa gaccacgtcc ttgccctgcg cgtcgtcggc
     5881 cgcgcagggg gtcgtgaccg cgccctcgcg ctccagccgc gcccagtcga tgtggtcgag
     5941 cgagcgcatc gcgcgcttca tctcggcgaa gacctcgcgc gggtgggcgt agtcccagtc
     6001 gaggccgagg cggcgggcga gctgctggat gatccaccag tccggtcgcg cctcgccggg
     6061 cagcgccacg gcggcgcggc cgagctggat ctggcggttg gtgttggtga cggtgccgtc
     6121 cttctcgggc caggccgagg cgggcaggat cacgtcggcg aactgcgcgg tctcggtgac
     6181 gaagaggtcc tgcacgacca ggtgctcgag cctggcgagc gcggcgcggg tgtggtggag
     6241 gtcggggtcg gacatcgccg ggttctcgcc caggatgtac atgccgcgca cctttccggc
     6301 ggcgatcgcg tccatggtct cgaccacggt gaggccgggc tgggcgggga gcggcgtcgc
     6361 ccacagctcc tcgaaggcgg cgcggtactg cgcgtcgccc accgggcggt agtcgggcag
     6421 caccatcggg atgaggccgg catccgaggc gccctgcacg ttgttctgcc cgcgcagcgg
     6481 gtgcaggccg gtgccggggc ggccgacgtg gccggtggcg agcgcgagcg cgatcaggca
     6541 gcgcgcgttg tcggtgccgt gcacatgctg cgagatgccc atgccccaga agatcatcgc
     6601 gcgcccggcg ttcgcataca ggcgggcgat gtcgcggatc tcgtccggcg ccaccccgca
     6661 cagcggcgcc atggcctcgg gcgtcatcgg cgcgacgtgg gcggcgagcg cctcgaagcc
     6721 ctcggtgcgc gcggcgatga agtcgcggtt gcacaggccc tcgccgatga tgacgtggag
     6781 catggcgttg aagagcgcga cgtcgccccc cggcgtgaag cgcaccatgc ggtgggcgtg
     6841 ctggccgagc accaggccgc gcgggtcgag cacgatcagc ttggtgccgc gcttggcggc
     6901 ctgcttgaac caggtggcgg cgacggggtg gttcaccgta gggttgcagc cggtgaggat
     6961 gaccacgtcg gcctgcgccg cctgcatgaa ggaggcggtg accgcgcccg agccgatgca
     7021 ctccatcagc gcggcgaccg agctggcgtg gcacagccgg gtgcagtggt cgacgttgtt
     7081 ggagccgaag ccggtgcgca ccagcttctg gaacagccag gcctcctcgt tcgagcactt
     7141 cgcgctgccg aagccggcga gcacgccggg gccgtgggcg tcgagcaggc ggcgcaggcc
     7201 ggcggcggcg aagtcgagcg cctcgtccca gcttgccggg cggaagtggc tgagcgggct
     7261 ggctgggtcg aaggccggat ccacgccctt gggcgagccc gcgcgacgga tcagcggggt
     7321 cgtcaggcgg ccgtggtggt tggggtagtc gaagccgaag cggcccttga cgcacaggcg
     7381 gttctcgttg gccgggccgt tgcggccctc gacgaagagg atgcgctcgt cccggatgtg
     7441 gtaggtgagc tggcagccca cgccgcagta ggggcacacc gaatccacct tgcgctcggc
     7501 gcaggccgag tcgccgcggc cgtccgcgtc gatcaggctg gccggcatca gcgcgccggt
     7561 ggggcaggcc tgcacgcact cgccgcaggc cacgcagctg ctgtcgccca tcgggtcgtc
     7621 gaagtcgaac acgatcgtcg cgcgcgcgcc gcggtgggcg aggccgatga cgtcgttcac
     7681 ctgcacctcg cggcaggcgc gcacgcacag gccgcaggtg atgcaggcgt ccagcgcgac
     7741 gtggatggcg gggtgggagc ggtcggccgg gcggggcgcg ggcgcgtcag tggccgcgtc
     7801 cgtggccgcc gcggcgggca gccgcatctg ctcgaccagc tcccagaaat ggctggagcg
     7861 gtccgggctg tccgcgcgcg ccggctggtg ctcgagcagc agttcgagca ccccctcgcg
     7921 cgcttgccgg gcgcgcgccg agctggcgct gcgcacgacc atgccgggcc gcgcttcgcg
     7981 gatgcaggag gcggccaggg tgcgctcgcc ctcgatctcg accatgcagg cgcggcagtt
     8041 gccgtcgccg cgatagccgg gggcgtcctt gaagcacagg tgggggatgc gctcgccggc
     8101 gcgcagcgcg acctgccaca gggtttcgcc ggggaaggcc tgcaccggaa cgtcgtccag
     8161 cgtgatctcg aaggcagcaa cggtcgcctc ccgcaggccg ggatgcaccg cgtcctgttt
     8221 ctgtaggagc ggcggcagcc gcgagctttt ggcttgttcc ccgcccgtcg tcggtgaaac
     8281 gggcggacgg tcgggcggaa tgctgctgcc gattgcgtct gcgtcggtgt tcacgatgtc
     8341 gcccggcgag ggcgaaaggc tcgcggctgc cgccgctcct acagggtggt cgatcgccgg
     8401 cgttcggggg cccatcagcg acgtggggtg gtcgatcggc gttgcagggg gcggggtctc
     8461 gtgcagcgtg gtgcccgcgc gcgcgagctc ggcggggaag aaacgcagca ggctcgcgac
     8521 cggattcggt gcggcctggc cgaggccgca gatggatgcg tcgcgcaggg tctgcgcgag
     8581 ggactggagg cgcgcgaggt cccagtcgtc ggcgcggacc tgttcgagca gcttctcggt
     8641 gccgaggcgg cagggcgtgc actggccgca ggactcgtcg gcgaagaagg cgagcaggtt
     8701 gtcggcgacg gcgcgcagtt cgtcctggtc cgagagcacg atgatcgccg ccgagccgat
     8761 gaagcagccg tggggctgca gggtgtcgaa gtcgagcggg aggtcggcga gcgcggcggg
     8821 gaggatgccg cccgaggcgc cgccgggcag gtaggcgagc aggcgatggc cgggctgcat
     8881 gccgccgcag tgctcgtcca ccagctcgcg cagcgtgatg ccggcggggg ccaggtgcac
     8941 gccgggcttg ttcacccgcc ccgacaccga gaagctgcgc agcccgctgc gcccgcgccg
     9001 gccctcgccg gcgaagggag cgccggcggc gagcagcggg atccagtaca gggtctcgac
     9061 gttgttcacc agcgtggggc ggccgaagag gccgagctcg gcgacgaagg gcgggcggtg
     9121 gcgcggcttg cccggcttgc cctcgagcga ctcgatcagc gccgactcct cgccgcagat
     9181 gtaggcgccg gcgccgcgac gcagcacgat gaagccgggc gcggcgaggc cggcggcctc
     9241 gagctcgccg atcgcctcgc gcagtaccgc gtgcaggccg gggtattcgt cgcgcaggta
     9301 gaggtagatc gccgccgcgt cgatggcgag cgcgctcgcc agcgcgcctt cgagcacccg
     9361 gtgcggcgcg gtctccagat agtggcggtc cttgaaggtg cccggctcgc cttcgtcggc
     9421 gttgaccacg aggtagcgcg gcgcggcgcc ggcgcgcacc gcctgccact tgcgcgcggt
     9481 cgggaagccg gcgccgccca gcccgcgcag gccggcttcg gcgagccggg tctgaagcgc
     9541 gtcgatggtg gtcgcgccgc tgcgcaggcg ctgcaccagg gcgtagccgc cggcggcgcg
     9601 ataggcggcg aggcgctgcc aggcgatggg ctcgggttcg aagtcgccgt gcgcgagcgc
     9661 agccccgacc gtggccgggg tggcgtgggt caggtggcgg cgaccgagct gggcgaccgg
     9721 ggcctgctcg cagcgcccca tgcagggcgc gcgcagcacg cggatgtgtg ccgggtcgag
     9781 ctcggcgtcg agcgccgccc gcagcgcctg cgcgccggcg agctggcagg gcagcgagtc
     9841 gcacacgcgc acggtgagcg ccggcggcgc gggctcgccc tcgcgcacca cgtcgaagtg
     9901 ggcgtagaag gtggcggtct cgtacacctc ggccatcggc aggttcatcc agtcggcgag
     9961 cgcgcgcagg tggcgcagcg agaggtggcc gaagcggtcc tgcagcgcat gcaggtgctc
    10021 gatgagctcg tcgcgatcgc ggcgggcgcc ggcgagcagg gtctcgagct cggcgagcgc
    10081 ggcggggtcg gtctggcggc cgcgcaggcc gggacgggtg cggcgaccgg tggcggcctg
    10141 gagcgatgag ggggaggcag aaggcatggc gatcggatcc ggagtgcggc gggcgcgggc
    10201 tcagcggcgc ccgacgaggc gcgcggcgcc gaccacgatg cgcgccatca gcgcgcgtac
    10261 ggcgtcgcca ccgggggagt cgagcgtcgg cgggcgccag gcgagggtgg cgtcgcgcgg
    10321 ggtgtgcggc agactgtaca ccgcgatcga cagcgggcac agcgcgatgt gctcgcgtgc
    10381 ctcggccacc aggcgggcgg cgaggccggc gctgcagaag ctgaggatct cggcgtcgcc
    10441 gtagagcgcg gggtcgtggc cgaggtcggg cgcggtgcgc tcgagcatgg cgccgaagcg
    10501 gctcaccacc ggcgcgctca ggccctcgtc ggcgatcgcg tcggcgagcg cctcgcgcag
    10561 gtcggcgaag ggcacgccgg ggaagtgctc gaccatgatg ccctcgccag gcgcggcgaa
    10621 gctcgtcgcc gacgcgaacg cgaacgcggc gcaggtggcg gccaggcgca gggtgcgcag
    10681 caggaaccgg gcgcgcggca ggcacagggc tgtggtgcgc ttgcgcggcg gcgttcgcgc
    10741 ggtcgcgcgc gccggccgca ggccgggtcg tgaagggatc ggtgccgtgc tcggccgcgc
    10801 ctcaggcgcg cttgttgctt cgttcatgtc ctcacctcga ccggagccgc aaggccatgc
    10861 gccccctcgt tgcacgattg ctgaccgcct ggatcattgc acaggccccc acctcggcgc
    10921 acgcgctcga tccggaggaa ctcgacgcgc tggtggcgcg gcccagcatc ggcctctaca
    10981 aggcctacgc cgagttcaag atggcgcgct acgacagcgc gcgcgagatc tggagcgcgc
    11041 tcgcgcaggc gggcgtggcg gaggcctggt tccacctcgg catcctcgcc gaggatggcc
    11101 tgggcgagcc gcgcgaccct gccgcggcgc tggagcgcta ccgccgcggc ggcgaagcgg
    11161 gctccagcaa ggcgcagtac cggctcgggc tgctccatct ggagggccgc ctggtgccgg
    11221 ccgacccggt gcaggcgcgc tactggctgg cggtggccgc cgccaacggc gatgaggagg
    11281 ccgcccgtcg gctgtctgcg ctgcccggac cgatgccggc cgggcagtga gaccgcgtgt
    11341 cggcgcgcgt cggcgggcct gacgcctgca tgccgcgccg gcgacggctt cgccgcacgc
    11401 tcggtgcggc tgcgaccgcg gcacccgcgt tgccaaactg gcgtgttcgg cgtgatcggt
    11461 gtgatcgcgg cgcgttcgag cgggtcccgc cccgctcagc gcgacgcctt cgcgcgcgcg
    11521 gcctcgagca cggcccgctc ggcggcgggg aagaggtgca ccaccgagcg gcggaactcc
    11581 tcgttgacca gcgccagccc ggcgaagcgc ggcgggatcg gggtctggaa gagctcggtc
    11641 atgtcctggc cggactcggc gccggcgcgg atggtttgcg ccagccagcc gaggtagtcg
    11701 cgggtctggc gcagcggggc gaggtcggtc gcgggctcgc cgtggcccgg cacccagcgg
    11761 cgggcgggca ggccttcgag ggtgtcgagc gcggccagcc agcgcgcgat gtcggcgtga
    11821 ggcgtggtgg gcgtgcggtc gtggaagagc aggtcggcgg cgtacaccgt gccgctgtcg
    11881 tggtcgatca ccaccaggtc ggcgacggtg tggccgccga gcgcgcgcag ctcgacgtcg
    11941 cgcccgccga tgcgctggcg tccggcggcg agcgcgcgct cggggacgac gacctcggtg
    12001 tcgcgcatcc agtcgccgtt gaggcggtac atgttggcgt tgaagccttc gccctcgctg
    12061 cggatcgcag cgatggtctc cggcagcgcc gcgagcgtgg cgcgcgggaa ggcctgattg
    12121 ccgaggaagt ggtcggggtg ctggtgggtg ttgaccacca gcacgatcgg caggggcgtg
    12181 acgcggcgga tggcggcgag catctgttcg ccgtagcgct tcgacgagcc ggtgtcgatg
    12241 acgatcacgc cctcgctgcc gacgatgaag ccggtgttga cgatgttgcc gccgttggcg
    12301 aaggagaaat cctccttgag gccgacgacg acccaggcgc cgggggcgag ctcgcgcggc
    12361 tgcaggcggt agtcgaagtc ctcggcgtgg accggcgggc tgatggcgag cagggtgcac
    12421 aacgcaaaga gcagcccggc gagcaggctc cgcagcgcgc ggacggcagg gcggcggtgg
    12481 agcgccgggg cggaggaggc ggatcggctc atcgggtcac ccaggcgtcg atgcggttgc
    12541 cgttgttgtc gcggccggcc acgtgcaggc gcgcgccggg ggctgcggcg cgcaggtcga
    12601 gcgtgaagct cgggttctcg gagaccggct cgagcggctg gatgcggctc agcgtgcggc
    12661 cttcggcgtc ggtgatcacg atgtcctcga tgtggaaggc ggggatgccg gcggccaggc
    12721 cggtgtccat cgggtggatg atgcgcatgc gcaggcgctc gccgccgtcg acccgcggcc
    12781 acagcttgcc gttgacctcg ttgaggcgct cctgccactc cggcgagccc gagcccaccg
    12841 acggcagcgt gcagccgccg ccggtggcgg tgacccaggc gccgccgaca tgccacacgc
    12901 cgtcggccgt gcgcgcggcg gctcgcaccg gcgaggactg ctgcagcttg atgcggaagc
    12961 ccaggcgcgg ctgggcggcg ccgggctcga agcgcagcgc cttgacgatc gggttgaagt
    13021 cggcgaacac gatcagctct tccaccgcgg gcaacccgct tgcatcgacg ctgaccggga
    13081 cgttgagcga atcctccgcg accgccgggc cgctcaccct gacgcgctcg tcgaagacca
    13141 ccgtggcgtc ggcgaagaag ctcttgcgca tatcctccca gcgcggcgag tcgagcgggt
    13201 cggcctgcgt gccggctgcc gcggtaggtg cagtgctggc ggagggggcc ggcgtggagg
    13261 cggcgggcac ggacgaggct gcctgcgccg gggcggcggc cgtggccaac atgcccaggg
    13321 cggtcgtggc cgcggcaatc caggcgaggg cgggacgggc ggacggtgtc atcgggactc
    13381 ctgtggttcg gcgcgcgatg cgcacgcctg ggtgcaggac gtcggtcatg caaaccacgt
    13441 gccagcgccg tcgtcacggc gccgttgcgg cttggccgcg cggaggcgcc ggccggagca
    13501 actcgcagca agggggctgt tccgaagcga aacaccctgt gctcaagtgt tacagcaggt
    13561 gttcggattg cgccggctgc tggagcagcg caggcgccga atagggcgcg cgcgggcctg
    13621 gcacgggctt tgcggtgatg tcgtggtccg gcacgtacgc ggcgccggaa gctacaccac
    13681 ccggaaaagc ttcgaaagaa acccaaggag gagtcgatga tgaaaaacga taagcgtccg
    13741 cgcagcctgc cggcaatgct gaccgcgctt acggtcgcgc tggctgcagc gggaatgggc
    13801 gccacggcgc aggccgcgag cgtgaccgac gaggacatcc tgaaggatgc cgagaccacc
    13861 catcagatcg tcaccaacgg cctgggcacc aagggccagc gctacagccc gctcgccaag
    13921 gtcaatgtcg acaccgtgaa ggacctggtc ccggtgtggg cgttctcctt cggcggcgag
    13981 aagcagcgcg gtcagcagtc gcagccgctg atccacgacg gcaagatgtt cgtgaccgcg
    14041 tcctatagcc gcatctatgc gctcgacgcc aagaccggcc agaagctgtg gaagtacgag
    14101 caccgcctgc ccgagggcat catgccgtgc tgcgacgtga tcaaccgcgg cgccgcgctc
    14161 tacggcgacc tggtgatctt cggcaccctg gatgcgcaga tcgtcgcgct caaccgcgac
    14221 accggcaagg tggtgtggcg cgagaagatc gacgactaca aggccggcta ctcgatgacg
    14281 gctgcgccgc agatcgtcaa gggcatggtc atcactgggg tgtcgggcgg cgagttcggc
    14341 gtcatcggcc gcgtcgaggc gcgtgacgcc aagaccggca agaaggtgtg ggtgcgcccg
    14401 gtggtcgagg gccacatggg ctacaagtac gacaaggacg gcaaggagat cgagaacggc
    14461 atctcgggca ccaccaacgc cacctggccg ggcgacctgt ggaagaccgg cggcgccgcg
    14521 acctggcaga ccgcctacta cgatccggat gtgaacctga tcttcatggg caccggcaac
    14581 ccggcgccgt ggaactcctg gctgcgtccg ggtgacaacc tgtactcttc ctccaccgtc
    14641 gcggtcgatc cggacaccgg caagatcgtc tggcattacc agaacacgcc gcacgacggc
    14701 tgggacttcg acggggtgaa cgaattcatc tccttcgagt acaaggatcc gaagagcggc
    14761 aagctcgtca aggccggcgc caaggccgac cgcaacggct tcttcttcgt caatgaccgc
    14821 accaacggca agctgctcgg cgcctatccc ttcctgaccc gcatcgactg ggccaagggt
    14881 tacgacctgg agaccggccg cccgatcacc aacgacgaca agcgtccgcc caatcccttt
    14941 gccgagggcg ccgccggcga gggcggcaaa ggcaagccgg tgttcgcggc gccgtccttc
    15001 cttggcggca agaaccagat gcccatgggc tacagccccg acaccggcct gttctacgtg
    15061 ccggccaacg agtggggcat ggacatctgg aacgagccgg tgagctacaa gcgcggcgcg
    15121 gcctaccttg gcgccggctt caccatcaag ccgctgtacg aggactacat cggcgcgatg
    15181 cgcgcgatcg acccggtcac cggcaagatc gtctgggagg tcaagaacaa cgcgccgctg
    15241 tggggcgggg tgctcagcac cggcggcaac ctggtgttct atggcacgcc cgagggctac
    15301 ctgaaggcgg tcaacgccaa gaccggcgag gaggcgtgga aattccagac cggctcgggc
    15361 gtgatcgcgc cgccggtgac ctgggaagtc gacggcgagc agtacgtcgc agtggtctcg
    15421 ggctggggtg gcgcggtgcc gctgtggggc ggcgacgtcg ccaagcgggt gaacttcctc
    15481 gagcagggcg gcaccgtctg ggtgttcaag ctgcacaaga gctgatcgcg gtgcctgcgg
    15541 cggcctgcgg gcggccgcag gccttggcgc cgcactcccc gcggcccgga cgcgatggcg
    15601 cccgggccgc gtcgtgtcgg gaggctgcgt gagcggctgc gggcgcggcg tgaggaacag
    15661 acaggatttt tcggcaacat ggagcatttc cgatgagaca gatacagcta tccagcttcg
    15721 ccaccgcggt cgtgctcgcg gtcggcgtcg ggacggccgc gcatgcggcc gaccgcgcga
    15781 cacctcgcga ggcgcgcacg atgttcgagc aggccgtgcg ctacatggag gagaacggcg
    15841 ccgagcgtgc ctttgcagcc ttcaacgacc gccagggcaa cttcgtccgc aaggacctct
    15901 acgtcttcgc gatcgacgac aagggcgtgt atcacgccag cggcgcggcg cccgaggcgc
    15961 tgctcgggct caaggtcctc gacaccacgg acgcggcggg caacccgctg ttccgcgaga
    16021 tgatcgacgc cacccgcgtc acccaggagg cgacggtgcg ctacgtgtgg ctgaaccgcg
    16081 cgaccaacaa ggtcgagccc aaggtgagct acgttcgcaa gctcggccag tacgtggtcg
    16141 gcgtgggcta ctcggcgccg cgcgcgagcg cggatgacgc gcgcgcgatg ctcgagcgcg
    16201 cggtagcggt ggcgcgcagc gagggcggcg cgcaggcggc ggcgcgcttc aacgaccgcc
    16261 gtggcgaatt cgtcaaggac gacctctatg tgttcatggt gaacatggag agcggccgct
    16321 tcgaggcgat gggcatgaac cccgccttgt ccgacaccga cgcgctcggc ctgcgcgacg
    16381 ccgccggcaa tgccttggtc gccgagatga tcgccaggct gcagaaggcc gacgaggcca
    16441 cggtcgatta cgtgtggcgc aacccggtga ccaacgcggt cgagaacaag cgttcctatg
    16501 tgcgcaaggt cgggacttcg ctggtcggcg tgggtcacta cctggagtga gtgcagttgg
    16561 ttgctccgtt atggagcaca tgctccagtg cggagcaggg tggagcaaca agaaggcccg
    16621 cgctgcgggc cttcgtcgtt ttctgggcgt tgagtgccgg cgactgcagc tgaattcgcg
    16681 cctgccggcg ctcctacatg aaccgccgcg cgtcccggac ctcctgtagg agctgcggca
    16741 gctgcgaacc cggcgctccg gtgatcgatg cgtttcccgg acgccaccgc cgccttttgt
    16801 tttctgtagg agcggcggca gccgcgaatg ggcggtggac gggcgaggcg tgtgggtggg
    16861 gatcgtgccg ccgtgttcgc gcctgccggc gctcctacat gaaccgccgc gcgtcccgga
    16921 cctcctgtag nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ctacatgaac
    17041 cgccgcgcgt cccggacctc ctgtaggagc tgcggcagct gcgaatgggg gggtgacggg
    17101 gcgaggcgtg tgggcggcag ttgtgccgcc gtgttcgcgc ctgccggcgc tcctacaaaa
    17161 accgacgtgt ttccggagtc ttgtaggagc ggcggcagcc gcgaaccttt ggagggatgt
    17221 gctcggtcgg cgctgcagcg aagcgtcagg gcgtgcgctg cttcaccccg tgtgcggcga
    17281 agatccggcc gagctcgccg gagcgctgca gctcggcgat cgcgcccgac aaggcctgct
    17341 ccaggccgcc gtgctcggcc ttgaccgcca tcccgagcgg ccaggagttg acccgcagct
    17401 cgggcatcga cagggtgtcg agcgcgatcg ccgcgtcgcc cccgagcgcg gcctcgagct
    17461 cggagcgcga ggccatgacc gcggcgacct cgccgcgctt catcgccgcc accgcctcgc
    17521 ccacgctgcg gaagtgggtg acgttgggct gcaggcggcc gcccaggatg tggcgcagga
    17581 aatcgcttgc gtgcgagtcg agctcggcgc cgatgcgctc ctgctcgaac accccgaagc
    17641 tggcgtcggc cgagccgccc ggggcgggga cgcgctcggg caggcgggcg agcgcgatgg
    17701 tctcgaggtg gtaggggccg aagatcttca cctgcttgtt ggcggcggcg aagcgcgggt
    17761 cgaccggcac gtgcagcatc acgtcgcccg gcttgtggcc gaggtagtgg ccacgccaga
    17821 ccatgttgcg caggtcgtcg ttcatgttct cgtcggcggg aaactccacg acctgcggct
    17881 gcaggcccag gcgttcggcg agggcgcgcc cgagcgcggt ctcgatgccc ttgccggcgc
    17941 tcgaccaggg cgcgaagttg gcgtagaccg cgacacgcag cgtgcccggc tgctgcaact
    18001 cgagctcggc cgcggccgcc cgtgccgggc tggcggcgag gacggcgagc gcgccggcgg
    18061 tgagcaggaa gcggcggcga tcagttttca tggacggtct ccagccaggc gcggatggcc
    18121 cacatggcct cctgggtcag catgccctcg aagggcggca tgtagaccgc gccgttgcgg
    18181 gtgacgccgt tgcggacctt gccgatgaag aactcgtcgg tgtcgtcgtc attgatgtcg
    18241 agcaggcgca ggtcgggtgc gatgccgccg gagaccgcgc cgaggccgtg gcagcgcgcg
    18301 cagttctggt tgaaggcgga gtcgccgatg cggatcgcgt ccttgttgcc gcggtagggg
    18361 ttcgctgtca cccaggtctc gccgagctgc ttgagcgagg acgtatcgac cgcctgcggc
    18421 gtgacgtcgc cgtgggcgtg cgcgaatgcg ccggcggtgg cgagggcgag gccggtcgcg
    18481 gtgatggcca ggcgcttgcg caggttctcc ttgatggtac gagtattcac cttgtcttcc
    18541 tcttcgatgt ggtggtgtgt cgatcaggtc cggttcaccc cggatgcagg tcctactgca
    18601 annnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ngtgttcgag cagatccgtg
    18721 cctcgggcag cctggtgatc ctgtccgacc cgcagggcat gatcctgcac agcctgggcg
    18781 acgccgagtt cgtcgaccgc gcgagccggg tggcgctgca gccgggtgcg tgctggagcg
    18841 aggctgcgcg cgggaccaac gccatcggga ccgcgatcgc gaccgccgcg cccacggtgg
    18901 tgctgggcgg ggagcactac ctcgaccgca acggcttcct gtcctgtacc gcggcgccga
    18961 tccgcgaccc gcgcggggcg ctcgcaggcg tgctcgacgt gtcctgcgag cagcgcatgc
    19021 accaacgcca ctccctcggc ctggtgcggc tgtcggtgca gctgatcgag aagcgcctct
    19081 tcgaggccga gttcgccaac cacatcctgg tcgccttcca cgagcgtccg gagtacgtcg
    19141 gcagcctgca ggagggcctg gtggcggtta cgccggaggg acacctggcg ggcgcgaact
    19201 cgatcgcgcg cgagtggatc gggcgccgcg tcgagtgcgg cggcggggcc tcgttcgccg
    19261 agctcttccg ccagggcctg ggcaaggtgg tcgatcgcgc gatgagctcg agcgacgcgc
    19321 tcatccggct cggcctgcgc gacggtaccg agatccacgt ccagctgcgc tcgctgcgcc
    19381 cgcgcttcac cgccttcggc gcgtcccagg ccggcgaggg cgggcgcagt ctcgcggcgg
    19441 agccgatgcc tgcggcggtc ggctgcgcgc ccccggctgc gccggtgaag gcggggccgg
    19501 tgaaggcggc ggaggggccg atcacgctcg cggatctggc taccggcgac gtgggcatcg
    19561 ggcgcgcggt cgatcgtgcg cggcgcatcc tcggcaagga catcccgctg ctgatccagg
    19621 gcgagtccgg cgtgggcaag gagctcttcg cgcaggcctt ccacaacagc gggccgcgcg
    19681 ccgacaggcc cttcgtcgcg ctcaactgcg ccgcggtgcc ggagaccctg atcgagtccg
    19741 agctcttcgg ctacgtcggc ggcgccttca ccggcgcgcg caaggagggt gcgatcggca
    19801 agatccagca ggcgcacggc ggcacgctct tcctcgacga gatcggcgat atgccgctgg
    19861 gcatgcaggc gcgcctcttg cgcgtgctgc aggagcgctg cgtgacgccg gtgggttcgg
    19921 tcaagtccat cccggtcgac atctcgctgg tgtgcgcgac gcaccgcgtg ctgcgcgatg
    19981 cggtcgcgcg cggcgagttt cgcgaggacc tctattaccg cgtcaacagc ctcaccgtga
    20041 ccttgcccgc gctgcgcgag cgcagcgaca tccgctgcat cgtcgagcgc attctcgccc
    20101 gcgagtgtcg cgaggccggg ctgcagggcg tgtggatcgg cgacgaggtg atgcgcttcg
    20161 tcgagcgcca cggctggccg ggcaacgtgc gccagttgca gaacgtgatc cgggtcgcgg
    20221 tggcgctact cgacgagggc gagcgcgaga ttcggccgga gcatctgccg gaggatctct
    20281 tcctcgccga tccggtcgac ggtgccaagg cgccgccggt cgcagcggcc gcgccggtcg
    20341 cgacggcggc gagtgccgcg gcgccgttgg tggccgatgc gctggcgagc cacggtgcga
    20401 agcgcctcga tcagctcgag atcgagctga tcgagcgtgt catgcgcgag gtcggcggca
    20461 acctgtcggc ggcggcgcgc acgctcgggg tgagccgcaa ccgcctctac cgcaagctcg
    20521 gacgcgcggg cggaacgtcc tgactcgggt aatccctgct tgcccgaggg caggcacgac
    20581 ctatgcttgt atttgcatag gtcgtgccgc gggcagtgct ctcacacccg ggcgaccgaa
    20641 cgctggaatc gataaacgac aaggagacga tcgatgtgga aagcactgca cattgatccc
    20701 gcgaagtgca ccggctgtct gcaatgcgag atggcctgtt cctacgagca caccggggtc
    20761 atcaatccga gcaagtcgcg catcaaggtg ttcaacttcg agcacgaggg ccgcaaggtg
    20821 ccctacacct gcacgcagtg caccgaggcc tggtgcctga actcctgtcc ggtggacgcg
    20881 atccgcatcg acctgacgac cggcgcgaag atggtgttcg aggacacctg cgtcggctgc
    20941 aaggtgtgca cgatcgcctg cccgttcggc accatcaact acaaccagga caccggcaag
    21001 gtgcagaagt gcgacctgtg cgagggcaac cccgcctgtg ccagcgcctg tccgaccggg
    21061 gcgatcacct atgtggacgc cgactggacc ggcatcgaca agatgcgcgc ctgggccgcc
    21121 aaggccaaca ccccggcttc ggccgctgcc tgaggaggat gcgtcatggg atggaatcgc
    21181 aaagtcctgc gcgtgaacct caccgcggga acctgtaccg aagagccgct taacatgcag
    21241 tgggccgacg aatacctcgg ctcgcgcggc ctggccacca agtacctggt gtccgagatc
    21301 gaccccaagg tcgatccgct gtcgtccgac aacaagatga tcatggccac cgggccgctc
    21361 accggcacca tggcctcgac cggcgggcgc tacacggtga tcaccaaggg gccgctgacc
    21421 ggcgcgatcg cgtgctcgaa ctcgggcggc ttcttcggcg ccgagatgaa gttcgccggc
    21481 tgggacatgg tgatcttcga gggccggtcg gcaaagccgg tgtggctcta catcgagaac
    21541 gacaaggccg agctgcgcga cgcctccggc ctgtggggca agagctgctg ggagaccgag
    21601 gagaagatca aggaagaact gcaggacccg ctggtgcgca tctcctcgat cggcgtcgcc
    21661 ggcgagaacc aggtgctcta cgcctgcatc gtcaatgacc tgcaccgcgc cgccgggcgc
    21721 tcgggcgtgg gcgcggtgat gggctcgaag aacctcaagg cggtggcgat ccgcggcacc
    21781 aagggcgtgt cgggcatcaa ggatttcggt gccttcctga aggccaccaa cgacgccaag
    21841 aaggtgctcg ccgacaacgc ggtcaccggc cagggcctgc ccaagtacgg cacccaggtg
    21901 ctgatgaacg tgatcaacga gatcggcgcg ctgcccaccc gcaaccaccg cgacgtgcag
    21961 ttcgaggacg cctcgaagat ctccgccgag gccatgcacg agaagcgcga gtccgacggc
    22021 aagacccact tggtgaccaa cgccgcctgc ttcgggtgca ccatcgcctg cggccgcatc
    22081 tccgagatcg acaagaccca cttcaccgtc aagaacagcc cgaagtactg gggcgcttcc
    22141 ggcggcctgg agtacgaggc ggcgtgggcg ctcggcgcgg ccaacggcgt gggcgacctc
    22201 gaggcgctgc agtacgccaa cctgatctgc aacgagcagg gcatggaccc gatctccttc
    22261 ggcgccaccg tgggcgcggc gatggagctc tacgagctcg gcatcctgac cgacgagaag
    22321 atcggcatgg ccgcgccctt cggctcggcg caggcgctgg cgaagatggt cgagatgacc
    22381 gcggtgggcg agggcttcgg caaggaactc ggcctgggca gcaagcgcct gtgcgagaag
    22441 tacggccgcc ccgagctgtc gatgagcgtg aaggggcagg aattccccgc ctacgactcg
    22501 cgcggcatcc agggcatggg cctggcctac gccacctcca accgcggcgc ctgccacctg
    22561 cgcggctaca ccgtggcgtc cgaagtgctc ggcatcccgg tcaagaccga cccgctcgcc
    22621 accgagggca agcccgagct ggtgaaggcc ttccaggacg ccaccgcggt gttcgactcg
    22681 gccggcatct gcgtgttcac cagcttcgcg tggaccctgg ccgacgtgca gccgcaggtg
    22741 gccgccgcgt gcgagggcga ctggagcatg gagaagctga acgaggtggg tgagcgcatc
    22801 tggaacatgg agcgcatgtt caacaacgcc gccggcttca ccgccaagga cgacaacctg
    22861 ccgccgcgcc tgacccagga agcggcgaag acggggccgg ccaagggcct ggtgaaccag
    22921 ctcgacaaga tgctgccgca ctactacgag gtgcgcgggt ggacgcccgc gggcgaaccc
    22981 accgcggaga cgcgggcgcg gctgggcctg taggttccgc ccaccctgta ggagcgccgg
    23041 caggcgcgaa cgacggcctg gttcgcgcct gccggcgctc ctacannnnn nnnnnnnnnn
    23101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    23161 nnnnnnnnnn nnnnnnnnnn nnnnnggagc gccggcaggc gcgaacgacg gcctggttcg
    23221 cgcctgccgg cgctcctaca ggggcgtcgt gacggctggt tcgtgcctgc gggcgcgcct
    23281 gcaggcgtgc tgtttacctc cgaagtgttt cacccgagga cgctgcaatg aaacacctga
    23341 ttctcggcaa cggccccgcg ggcgtcgttg ccgccgagac cctgcgcaag gtcgcgccgg
    23401 ccgacgacat cctgatggtc ggctttgaag acgcgccgcc gtattcgcgc atggcgattc
    23461 cctacctgct cgaaggcaac atcgacgagt cgggcaccta cctgcgcaag gacgccggcc
    23521 acttcgagcg cctgcgtatc cgccagctgc gcggccgtgc ggtcgcgctc gacaccgaca
    23581 agcgcaaggt gctgttcgac gacggtcact tcgagcacta cgaccgcctg ctcatcgcca
    23641 ccggctcgca tccggtgcgt ccgcccatcc cgggcgtgga cctaccctcg gtgcacacct
    23701 gctggacgct ttccgatgcg cgcgcgatcg ccgcccacgc caaaccgggt gcgcgcgtgc
    23761 tgcagttggg tgccggcttc atcggctgca tcatcatgga ggcgctcgcc aagcgcggcg
    23821 tgcagctcac cgtggtggag atgggcgacc gcatggtgcc gcgcatgatg acgcccaagg
    23881 ctggcggcat gatcaagcgc tgggtcgagg acaagggcat ccgcgtgctc acctcggccg
    23941 gcgtgcagcg catcgaccgc ggtggcgacg tggacagcga tgcgccgctg gtggtgagcc
    24001 tgtccaccgg cgatcgcctc gactgcgacc tcgtgatcgt cgccgcaggc gtggcgccca
    24061 acgtcggctt cctggacgag acgccggtgc atgtggccaa gggcgtgctg gtgaatgacc
    24121 acatggagac cagcgttccc ggcatcttcg ccgctggcga cgtcgccgag gcgcccgacc
    24181 tgttcaccgg cgcacacttg gtgtcggcga tccagcccaa cgccgcggac caggcgcgca
    24241 tcgccgccac caacatggcg cgcgacctcg tgtacgagtc gcgcctcaac ggcgtgctgg
    24301 cgatcaacgt gctcgacacg ctcgggctga tctcgtcctc cttcggccag tggtggggag
    24361 agaagcccga ggccggcggc agcggcgtgg agatggtcga cgaggcgcgc tatcgctacc
    24421 tgagcctgca gttcaaggac gacgtgctgg tcggcgccac ctcgatcggt ctgacccagc
    24481 acgtcggcgc gctgcgcggg ctgatccacg gccaggtgag gctgggcgac tggaaggatc
    24541 gtctgctcgc caacccgctc gccttcgtgg atgcctacgt cgcgcgcagc cagcagccga
    24601 tggcgctggc gcgctgaggg ggccgacttg gagactcgtg tgacgatccg catcgccttc
    24661 aagctcttcg cctcgctgtc ggactacctg cccagcggcc atcgcggcaa ccggctcgag
    24721 ctcgaggtgg acgagggcac cacggtggcg gagatgatcc ggcgctacaa cgtgcccgag
    24781 cgcagcgcgc atctggtgct ggtgaacggc cacttcgtgc cgccttccga gcggccgcgc
    24841 aagcggctgg ccgagggcga cgagctcgcg atctggccgc cgatcgccgg cggctgaagc
    24901 ggtggccttc atcgccggcc cggtccccga gtccttcgaa cgccgggtca ccgccacgcc
    24961 gcaggagttc gcgcgcgacc tgcgccaggc ctggccggcg gtcgtcgccg aggccggcgg
    25021 cttgcgcttc agcctgcacg agggcgtgca ggccctcgtc attgccatcg agcccgccgg
    25081 cgtgcgtcgg ctgggcctct tcgagctgcc ccagctcgac gtgcgctttc gcttcggccc
    25141 cggcgaggag ccggcgcgcc gcgcactgct cgcacgcctg gaccgcggga tgcagaaggg
    25201 cgggggttga gcggcgcggc ggctggcctc atcctgtgta cgcttcgaat cgtttcttga
    25261 aggactgccg atgagccatg gatacgtggt gggccacatc acggtgaagg atgccgacaa
    25321 gtgggcggag taccgcggca aggtgccgga cacgctggcg ccgtggggag cggaactcct
    25381 gtttcggggt caccgggtgg cgagcttttc cggcgacagc ccgcatgcgg acatcgtcgt
    25441 catccgcttc ccgagcgcgg cggcggcgag cggctggttc gcctcgccgg cctaccaggc
    25501 cctgatcccg ctccgcgagc aggcggccga ggtcctgctg ctgtcctacg aggactagcc
    25561 cgcggggcct ttgccgcttg cgggcgcccg agcgaggccg cgaagggccc gtcggcgttc
    25621 cggctgcggg ggcgtttccg gtatcctccc cgccgatgtc cgccttcgcc gccaccttct
    25681 ccgacgcgct ttcgctgctc gcccatttcg accacacggt gctcgagatc gtcgcgctgt
    25741 cgctgcaggt cagcggcgcc gcggtggtgc tcggcacgct gatcgggctg ccgctcgggg
    25801 cctgcatcgc ggtcggccgc tttccgggca agaccgcgct gtcggtgctg atcaacggca
    25861 tgatgggcct gccctcggtc gtcgtgggcg tggtggtgta cctgatcctg tcgcgctcgg
    25921 ggcccttcgg cgcgctcggc atgctgtatt cgccggcggc gatggtggtg gcgcagaccc
    25981 tgctggtggt gccgctgatg gcggcgatca cccgccaggt ggtggaggac gtttgggcgc
    26041 gctacgccga ggaactgcag gtgatgcgct tctcgtggtg ggacagcgtc accacgctgc
    26101 tccacgactg ccgccactca ctggtggtgg cggtgctcgc gggcctgggg cgggcgatga
    26161 gcgaggtggg cgcggtgatg atcgtcggcg gcaacatcga cggcgccacc cgggtcatga
    26221 c
//
LOCUS       DAOTIN010000041        26063 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_2160_length_26063_cov_9.134189, whole genome shotgun sequence.
ACCESSION   DAOTIN010000041 DAOTIN010000000
VERSION     DAOTIN010000041.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 26063)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 26063)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26063
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2160_length_26063_cov_9.134189"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..563
                     /locus_tag="P5537_08190"
     CDS             <1..563
                     /locus_tag="P5537_08190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HRV78059.1"
                     /translation="AVLDGTDAVMLSAETAAGKFPVEVVEAMSRVCLEAEKSYDTGLD
                     REMLDRVFTRIDQSIAMAAIWTAYHLKVKAIASLTQTGSTALWMSRLIAGVPIYALTP
                     EVSARNQMTLYREVHPLLMSQTHQDRDVLLWEAEQVLLEQGVVDYGDLIVLTIGEPIG
                     SSGGTNTLKIVRVGEHHRPGTLDDPV"
     gene            671..1735
                     /gene="fba"
                     /locus_tag="P5537_08195"
     CDS             671..1735
                     /gene="fba"
                     /locus_tag="P5537_08195"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929444.1"
                     /note="catalyzes the reversible aldol condensation of
                     dihydroxyacetonephosphate and glyceraldehyde 3-phosphate
                     in the Calvin cycle, glycolysis, and/or gluconeogenesis;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase class II"
                     /protein_id="HRV78060.1"
                     /translation="MPLVSMRQLLDHAAEHSYGLPAFNVNNLEQVQAIMEAAAECDAP
                     VIMQASAGARKYAGEAFLRHLIDAAIEAYPHIPVVMHQDHGQSPAICMGAIRSGFSSV
                     MMDGSLLEDGKTPSSYEYNIAVTREVVKFSHAIGVSVEAELGCLGSLETGQAGEEDGV
                     GAEGTLDHSQMLTDPDQAADFVKQTDCDALAIAIGTSHGAYKFTRKPTGDILAIERVK
                     AIHARIPNTHLVMHGSSSVPQELLEIIRQYGGDMKETYGVPVEEIVQGIKYGVRKINI
                     DTDIRLAMTGAIRKFMFENPSKFDPREFNKPAREAAKLVCKARYEAFGCTGMASKIKP
                     VSLDKIAARYKAGELTQIVR"
     gene            complement(1814..2734)
                     /locus_tag="P5537_08200"
     CDS             complement(1814..2734)
                     /locus_tag="P5537_08200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HRV78061.1"
                     /translation="MKLAQRLTLKQLRALVAVADSASFTQAARLLHLTQPAISMQIRD
                     AERIVGQVLVDGRREVRLTPAGEVLVRAARQVLHSLELAEVELKARIGVAAGTLDVVA
                     ITTAEYFVPYLLAEFGRRFPDITFRLTVANREHVRALLQEQRCDVAIMGQPPRGLDLR
                     RIPFAPHRLSFVARPDHRLAGRTRIPPAALTGERLLLREQGSGTRDNLERFLRAHGVK
                     PLAADELGSNETLKQAVMAGMGIAFLSHHTFAMEVESGRLLRLDVADTPVIREWNVVS
                     RTDRPMTPALDALLDFLQTEGAARMRAMEC"
     gene            2856..4322
                     /locus_tag="P5537_08205"
     CDS             2856..4322
                     /locus_tag="P5537_08205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="form I ribulose bisphosphate carboxylase large
                     subunit"
                     /protein_id="HRV78062.1"
                     /translation="MGAADTPQQIIDPRKRYQAGVLKYAQMGYWNADYAPKDTDVLAV
                     FRITPQEGVDPIEAAAAVAGESSTATWTVVWTDRLTASDMYRAKAYRIEPVPGQEGQY
                     FCWVAYDLDLFEEGSIANLTASIIGNVFSFKPLKAARLEDMRLPVAYVKTFRGPPTGI
                     VVERERLEKYGRPLLGATMKPKLGLSGKNYGRVVYEALRGGLDFTKDDENINSQPFMH
                     WRDRFLYCMEGVNQAAAQTGESKGHYLNITAGTMEEMYKRAEFARDLGSCIVMIDLIV
                     GWTAIQSISNWCRDNDMILHMHRAGHGTYTRQKNHGVSFRVIAKWLRLAGVDHLHAGT
                     AVGKLEGDPMTVQGFYNVCRDTYTKQDLTRGLFFDQDWASTKRVMPVASGGIHAGQMH
                     QLLTLFGDEVVLQFGGGTIGHPMGIQAGATANRVALEAMVLARNEGRDIANEGPQILA
                     DAARWCQPLRAALDTWGEITFNYTSTDTADFVPTASVA"
     gene            4349..4774
                     /locus_tag="P5537_08210"
     CDS             4349..4774
                     /locus_tag="P5537_08210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose bisphosphate carboxylase small subunit"
                     /protein_id="HRV78063.1"
                     /translation="MRITQGCFSFLPDLSDKQIAAQINYCLDQDWAVAIEFTDDPHPR
                     NTYWNMWGLPMFDLRDPAGVMGELEACREANPETYIRINAFDSTKGWETVRMSFIAQR
                     PSVEPGFRLVRQETQGRQLRYTMESYAVGRNPEGARYAG"
     gene            4893..5795
                     /gene="cbbX"
                     /locus_tag="P5537_08215"
     CDS             4893..5795
                     /gene="cbbX"
                     /locus_tag="P5537_08215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CbbX protein"
                     /protein_id="HRV78064.1"
                     /translation="MNAPEQATAIDLAAEFRDAGIGEVLEALERDLVGLAPVKRRVRE
                     IAALLLVDRVRQRLGLATEPPSLHMSFSGNPGTGKTTVAMRMAEILHRLGYCRRGHVV
                     AVTRDDLVGQYIGHTAPKTKEVLKRAMGGVLFIDEAYYLYRPENEKDYGQEAIEILLQ
                     VMENQRDDLVVILAGYADRMERFFESNPGMKSRIAHHVDFPDYSDAELGEIARRMLAG
                     WNYRFDDAARRAFDEYIVLRRTQPHFANARSIRNALDRMRLRQALRLFDSGATVDAGA
                     LTTITEADVRASRHFRPDEAASPQ"
     gene            5880..6968
                     /locus_tag="P5537_08220"
     CDS             5880..6968
                     /locus_tag="P5537_08220"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 fructose-bisphosphatase"
                     /protein_id="HRV78065.1"
                     /translation="MFSLDRSTLTEYLIEHRRHNPEATGEFNALILQVAQACKAISRA
                     VAHGALADVLGSHGSANVQGEEQKKLDVLADDIFLRATHWGGDLAGMVSEENEAPIPL
                     PASDQRGKYLLAFDPLDGSSNIDVNVAVGSIFSILRAPTPGEDATAEDFLQPGNRQVA
                     AGYAIYGPSTMLVLSVGSGVAGFTLDPIIGEFYLTHPDIRVPATTREFAINTSNARFW
                     EPPVRRYVDECLAGRTGPRGVDFNMRWIASLVAETHRILMRGGVFLYPRDRKDPTKPG
                     RLRLLYECNPIGFLIEQAGGRASTGVRPVLEVRPEGLHQRIGFVFGSKDEVERIERYH
                     SEPVIGGAQDELPLFQPRSLFRDTEFTQ"
     gene            6984..7865
                     /locus_tag="P5537_08225"
     CDS             6984..7865
                     /locus_tag="P5537_08225"
                     /EC_number="2.7.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008974 - phosphoribulokinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HRV78066.1"
                     /translation="MSERHPIVAITGSSGAGTSTVQRTFEEIFRREGVTAAVIEGDSF
                     HAYDRKTMREKLAACDLDGNCQLSHFGPEANLFGEIENLFRSYAESGTGKRRKYLHSP
                     EEAEPWKQEPGTFTPWEELPTGTDLMFYEGLHGAVQHENIDVARFVDLLIGVVPVINL
                     EWIQKLNRDKSMRGYSTEAVTDTILRRMHDYVHYICPQFARTHVNFQRVPMVDTSNPF
                     IARAIPTADESMVVIRFANPKGIDFPYLLNMINDSFMSRANTIVVPGGKMELAMQLIF
                     TPFIWRLMDRRRKALAQ"
     gene            8103..10211
                     /gene="tkt"
                     /locus_tag="P5537_08230"
     CDS             8103..10211
                     /gene="tkt"
                     /locus_tag="P5537_08230"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HRV78067.1"
                     /translation="MNMRLTQAPIDTLCANALRFLAIDAVEAAKSGHPGMPMGMAEIA
                     VALWTRHLKHDPADPAWADRDRFVLSNGHGSMLLYALLHLSGYELPLDELKRFRQLDS
                     RTPGHPEVGHTPGVETTTGPLGQGLTNAVGMALAEKLLAAEFNRPGHPLVDHRTWVFL
                     GDGCLMEGISHEAASFAGVQRLSKLICFWDDNGISIDGDVSGWFADDTPARFRAYGWN
                     VVEAVDGHDVAAVDRAIQMALGNAEADTGPTLICCRTDIGHGSPGRAGTADVHGAPLG
                     AGEITATRGALDWPHLPFEIPGEVRAAFDARARGAAQHDEWRARLDAYTQAFPEEAEE
                     FCRRMAGALPVSFPVLSNAILRGVDKEAAELATRKASQQAIGRLARALPELLGGSADL
                     THSNLTDWPGCGAVRADAPGRHINWGVREFGMAAALNGIALHGGFIPFGATFLVFSDY
                     ARNAIRMSALMKQRVVYVMTHDSIGLGEDGPTHQPVEHIPSLRLIPGLDVWRPCDAVE
                     TQAAWNAAVARRDGPTLLALSRQNLPHQARDEVQIQAILRGGYVLADADAPALVIIAT
                     GSEVALAMAARAALAAEGVGVRVVSMPCTTLFDRQTDEWRRSVLPAGVPRLVIEAARG
                     DAWWRTIASDGGRGGDVIGMECFGESAPAGALLARFGFTPAAVLERARALLAATNQPG
                     PAAMHGTAPLPETRKISNGS"
     gene            10216..11454
                     /locus_tag="P5537_08235"
     CDS             10216..11454
                     /locus_tag="P5537_08235"
                     /EC_number="2.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HRV78068.1"
                     /translation="MNFLRLAELDLAGKRVFIRADFNVPFNADGTLSDDTRIRATLPA
                     IHHCLEAGAAVMVTSHLGRPTEGALTAADSLAPVAATLSDLLGRPVPLIRDWTGGGFT
                     VRPGEVVLLENCRGNVGEKVDDPRLAARIASFIDVYVNDAFGTAHRSECTLHALALAA
                     PVACAGPLMTAELDALGRALAQPARPLAAIVAGSKVSTKLTILESLADKVDVLVVGGG
                     IANTFLAARGCEVGASLHEPDLLEAARRVERRLAERGGVVWLPEDVVVADRFAADADT
                     RICDAESVPPGWMILDIGPNSRDSLAGVLARAGTIVWNGPVGVFEMDAFAAGTRALAE
                     AIAASPAYSIAGGGDTLAAIARFGVGGRIDYISTGGGAFLEFLEGRELPAVTALRARA
                     RPASRRVEPVPQFEHEPELT"
     gene            11475..12524
                     /gene="fba"
                     /locus_tag="P5537_08240"
     CDS             11475..12524
                     /gene="fba"
                     /locus_tag="P5537_08240"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262951.1"
                     /note="catalyzes the reversible aldol condensation of
                     dihydroxyacetonephosphate and glyceraldehyde 3-phosphate
                     in the Calvin cycle, glycolysis, and/or gluconeogenesis;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase class II"
                     /protein_id="HRV78069.1"
                     /translation="MAMIALRQLLDHAAEHDYGVPAFNINNMEQIQAIMLAAEATDSP
                     VILQASAGARGYAGEAFLKKMVEAAVEQWPDLPICLHQDHGASPAVCQQSIRSGFTSV
                     MMDGSLREDMKTPASYDYNVDVTRRVVEMAHAVGVSVEGELGCLGSLETGQAGEEDGV
                     GAEGTLDHSQMLTDPAEAADFVAATGVDALAVAIGTSHGAYKFTRPPTGDILAIERIA
                     AIHARIPKTHLVMHGSSSVPQEWLAIIREHGGEIGETYGVPVEAIVQGIRSGVRKVNI
                     DTDLRLAMSGAMRRLMATDRKEFDPRKFFKAARDAARDICRERFEAFGCAGRASRIKP
                     LALEKLARRYAAHRG"
     gene            12746..14047
                     /locus_tag="P5537_08245"
     CDS             12746..14047
                     /locus_tag="P5537_08245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3422 domain-containing protein"
                     /protein_id="HRV78070.1"
                     /translation="MSSLFEQHPLRQVLNDEVHARPPVPLDTPEFVTYLAFLHHEGSA
                     GREADHLAALAGQLGQPAPNIESGHVLLEAEGFRLKWERHNEFSSYCFFRRIEPGDSP
                     DDYALLHVPAAWRKAIPGLLIAATHIELRSIAEVPLESVLHQQSRHGQALVASGVSDG
                     AGWVLTDFHLHDGFSHFLLLDNGFTPRQAGRIAQRLVEIETYRVMALLAFPVAKDTGR
                     LVSRAEDELADLMDGMGQSRSAEDDRAVLARLSRLAAEVERSVARTTFRFGAAGAYYR
                     LVRQRIDDLREDRLPGFSPIGEFMDRRLVPAIDTCTSIARRQDDLSGRIARNSQLLRT
                     RVDIEIERQNQELLAQMNRRAKIQLHLQETVEGLSVVAITYYASQLVNYVSKGAKHLI
                     EPLTPEVLTAVSIPVIAGVVYMGLRRMRKLLGAEEDGQAHP"
     gene            complement(14089..15222)
                     /locus_tag="P5537_08250"
     CDS             complement(14089..15222)
                     /locus_tag="P5537_08250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tat pathway signal protein"
                     /protein_id="HRV78071.1"
                     /translation="MERRRFIGAAALAGLGVAGGAGYLSQVRGAAAYEAAADSTWRHG
                     EPLQGDARAVLRELVRYATLAPSSHNTQCWKFALAERAVSIFPDYARRCPVVDPDDHH
                     LFVSLGCAAENLVQAAPAMGLHCEPALVTEADETAPAGEGGGPVLCALAPAASRRSAL
                     FEAIPLRQSTRGEFDSRPLSNAELRLLEAAGTGRGVRVRLLTAAPDLERVLEFVVAGN
                     TAQMRDPAFVRELKAWIRFNGGDAARLGDGLFAGASGNPTAPAWLGSLLFDAFFTEQA
                     ENDKYARHVRSAAGIAVFVSERDDRAHWIEAGRCFQRFALQASALGVRSAHLNQPVEL
                     AALRPAFGAFLGIAYGRPDLVIRFGRGPAMPRSLRRPLDAVLT"
     gene            15398..16060
                     /locus_tag="P5537_08255"
     CDS             15398..16060
                     /locus_tag="P5537_08255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protocatechuate 3,4-dioxygenase"
                     /protein_id="HRV78072.1"
                     /translation="MSSHSGLRRRLVLGGSATLLSAPLAAAQRALTPSQMLGPFYPVT
                     PPLHQDNDLTRVEGRSGRAAGQIVDLSGRVLDFDGRPLAGVRVEIWQCDANGRYRHPR
                     DPGDVEEDPNFQGFGHTVTDADGHYRFRTIRPVPYPGRTPHIHAAVIQEGARPFVTQI
                     YVAGEPLNLRDGLFMRVPEALRPLLLADFVPANDPVATLSASFDFVLAPVLAGLFEAH
                     TV"
     gene            16447..17382
                     /locus_tag="P5537_08260"
     CDS             16447..17382
                     /locus_tag="P5537_08260"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HRV78073.1"
                     /translation="MATPIFETSIQSLPLLGRGKVRDIYAVDADKLLIVTSDRLSAFD
                     VILPDPIPDKGRVLVALANFWFDRLGHILPNQLTGIDPETVVAADEREQVRGRALVVK
                     RLKPLPIEAVVRGYVIGSGWKDYQATGAICGIALPAGLQQAAKLPAPIFTPSSKADMG
                     EHDENISFEQAQARCEALMKDALAGTGKTGAQLAEEARAAAIALYSEAAEFAATRGIL
                     IADTKFEFGIDAAGTLHLIDEALTPDSSRFWPADGYREGISPPSFDKQYVRDYLETLD
                     WNKTAPGPKLPAHVIEHTAAKYREAYERLTGRKLD"
     gene            17615..18388
                     /locus_tag="P5537_08265"
     CDS             17615..18388
                     /locus_tag="P5537_08265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2189 domain-containing protein"
                     /protein_id="HRV78074.1"
                     /translation="MDKPYGSLEQHFDLPKIRTVGHDRPLQWLRAGWRDLRENLGASL
                     AYGILLSAIGYAILAYAADRPYLFIAAISGFMLIGPLAAAGLYELSRRSEEGERIGFL
                     GSLRGLARNADSLAFFGAFLAIALLAWERLSAILFALFYRGDVDNVTNFVAGVLAAND
                     NLYFVFAYLMVGAVLALVVFSLSAIAIPMLLDRDTDAFTAAMTSLRAVQVNFDTMALW
                     ALLLVAMIGIGFATMMIGMVILLPLAGHATWHAYRELVR"
     gene            18498..20606
                     /locus_tag="P5537_08270"
     CDS             18498..20606
                     /locus_tag="P5537_08270"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family metallopeptidase"
                     /protein_id="HRV78075.1"
                     /translation="MQQGTRPSPANPLLDFAGMPRFADIRPEHVEPAIRGLIDENRAL
                     IERLTADPATPSWDRFVAPMEEAGERLGRAWGVVGHLHSVFDVPEWREAYNAMLPEIS
                     RFYAEVGQNLTLFEKYKALHDSPEFATLSAVRQRILDHALRDFRLSGAELPDEQKPRF
                     QAIQEEQSQLAAKFSENLLDATNAHAEWIADEAGLSGIPEDAREAARAAAEAEGKPGW
                     KFTLQMPSYLPVLQYADDRELRARMYRAYATRASELGDPELDNGPLIGRILALRHEEA
                     RMLGYRNFAEVSLVPKMADTPEQVLGFLHDLAAKAKPFAEKDLQELKVFAKAELGLDT
                     LEPWDVAYASEKLREQRYAYSDQEVKQYFPEPKVLDGLFGVIRALYRVDILPDEAPSW
                     DPDVRFFRIEKDSANGPELVGHFYLDLHARSTKRGGAWMDSARSRHRNTWGSDTPVAY
                     LVCNFPGPVGEGTKKRPATFTHDDVLTLFHECGHGLHHLLTQVDELAVSGIHGVEWDA
                     VELPSQFMENFCWEWDVLQGMTAHVDTGEPLPRALYDKMIAAKNFQSGMQTVRQLEFS
                     MFDLRLHGEVDASSGPVPIERVMALLDEVRKEVAVMIPPAWHRFPHSFSHIFAGGYAA
                     GYYSYKWAEVLSADAFEAFEEAGAGKGSLLDPETGERFWREILAVGGSRPALDSFKAF
                     RGREPKVDALLRHSGMVAQA"
     gene            20700..20984
                     /locus_tag="P5537_08275"
     CDS             20700..20984
                     /locus_tag="P5537_08275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HigB family
                     toxin"
                     /protein_id="HRV78076.1"
                     /translation="MKLISNKALRDFSACHADAECPLQAFRQLIEKGHYPHFAALRAT
                     LRGVDKVGERYVFNIGGNKYRLIAAIAFTPQLLWVKAVLTHADYDEGDWK"
     gene            20981..21388
                     /locus_tag="P5537_08280"
     CDS             20981..21388
                     /locus_tag="P5537_08280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HRV78077.1"
                     /translation="MSVTDVLAPWAAINDALGLSAPIRDEAHYAELLAFVDEAFEQFG
                     GNDEHPIFGLVSIVADRIREYEARVHPWPELPPSELLRELMAEHGIRQSDLPEVGTQS
                     VVSEVLAGKRGLNLRQVKALSVRFRVPMEVFAA"
     gene            21501..22265
                     /gene="xth"
                     /locus_tag="P5537_08285"
     CDS             21501..22265
                     /gene="xth"
                     /locus_tag="P5537_08285"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008853 - exodeoxyribonuclease III
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HRV78078.1"
                     /translation="MKIATWNVNSLKVRLPHVLDWLAANKPDALCLQELKLEDKAFPV
                     ADLEAAGYHAVFIGQKTYNGVAILSPQPIDEASVVRNIPGFEDEQKRIIAATIDSVRV
                     VCGYFPNGQAVGSDKFEYKLRWLAALTEWLREELKTHERLVLAGDFNIAPEDRDAHPD
                     WKDEIHVSAPERAAFRALQELGLIDAFRLFEQPERAFSWWDYRMMAFRRNFGLRIDHL
                     LVSPALREACRSCSVDKEPRRLERPSDHAPVVLELA"
     gene            22270..22956
                     /locus_tag="P5537_08290"
     CDS             22270..22956
                     /locus_tag="P5537_08290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HRV78079.1"
                     /translation="MSPSLSPTDTTQLDARYPVLADLSAPARTRLLHSAQWMRVPAGA
                     MLFDDRQACEGFPFVVEGSVRVSKCAPSGRELPLYRVGPGETCIISSSCLLGHEDYNA
                     RGVTESDTLLMLLPKAVFDEMMGERPFRDFVFHLFAERIADLMQLIEEVAFRKLDQRL
                     AALLLGKGRVLHVTHQQLADELGSVREIVSRLLKSFAEQGLVKLAREQVEIIDPSGLR
                     RMASEGKGAA"
     gene            23105..23296
                     /locus_tag="P5537_08295"
     CDS             23105..23296
                     /locus_tag="P5537_08295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004354734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2892 domain-containing protein"
                     /protein_id="HRV78080.1"
                     /translation="MKTNVGGADKILRIVAGIALLAWAVFGGPVWAWIGIVPLATGLL
                     GWCPAYTMLGMNTCPLSKK"
     gene            complement(23342..24160)
                     /gene="rsmA"
                     /locus_tag="P5537_08300"
     CDS             complement(23342..24160)
                     /gene="rsmA"
                     /locus_tag="P5537_08300"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004354733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HRV78081.1"
                     /translation="MHDFDTDGHRARKRFGQNFLSDPNIIRKIIDGIRPQPGELMVEI
                     GPGLGAMTDPLIERLGHLHVVEIDRDLIARLHERYTAEQLTVHEGDALKFDFASLCAG
                     VEGGGERSLRIVGNLPYNISTPILFHLAGFADQVRDMTFMLQKEVVMRMVAEPGTEEY
                     GRLSVMLQYRFRMGRLFDVPPGAFRPAPKVMSSIVRMAPLPADQLGARDEALLGRIVA
                     AAFGQRRKTLRNTLREFIDETGLQALGIDPGLRGEKLSVEQYVAIANECAGREA"
     gene            complement(24205..25221)
                     /gene="pdxA"
                     /locus_tag="P5537_08305"
     CDS             complement(24205..25221)
                     /gene="pdxA"
                     /locus_tag="P5537_08305"
                     /EC_number="1.1.1.262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050570 - 4-hydroxythreonine-4-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxythreonine-4-phosphate dehydrogenase
                     PdxA"
                     /protein_id="HRV78082.1"
                     /translation="MSAAAHAGCGLVAITSGEPAGVGPELCLRLAERAWPLRPVVLAD
                     LGLMRARAAALGSAMGVVEFDPVRPAPAGTVEVLHLPLAAPSRPGVLDAANGAYVLRL
                     LDRAIAGCVQGEFAAMVTAPVHKGVICEGLGARETMPFTGHTEYLAEHTGTSRVVMML
                     VGGGLRVALATTHLPLAAVPAAITPQVLEDTLRILHADLRRHFGLAAPRILVAGLNPH
                     AGEGGHMGREEIDVIIPVLERLRAEGMQLVGPLPADTLFVPHTLAQGDAVLAMYHDQG
                     LPVLKHASFGGGVNVTLGLPIIRTSVDHGTALDLAGSGRADPGSLFAALELAIAMTQA
                     RAAA"
     gene            complement(25269..>26063)
                     /locus_tag="P5537_08310"
     CDS             complement(25269..>26063)
                     /locus_tag="P5537_08310"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HRV78083.1"
                     /translation="DAFSGQEFAVAHILLRTPEGASPQQVEAVARRAEQVMARLRSGE
                     DFARVAAEVSDAPDGLQGGGLGWRPLDRLPALFADAVRRMRPGETSPVLRSAAGLHIV
                     RLVDVRGGGQMAVQQLEQTRARHILIKTSEVLSDADAEARLLGIRERVINGADFAELA
                     KASSADLSAARGGDLGWLNPGDTVPEFERAMNALQPGAVSAPVRSPFGWHLIQVMERR
                     VQDVTDERKRAAARQALRERKAEQAYEDWVRQLRDSTYVDYRIERE"
BASE COUNT         4154 a         9775 c         8413 g         3721 t
ORIGIN      
        1 acgcggtgct cgacggcacc gacgcggtga tgctgtcggc cgagaccgcc gccggcaagt
       61 tcccggtgga ggtcgtcgag gccatgagcc gggtctgcct ggaggcggag aagtcctacg
      121 acaccgggct cgaccgcgag atgctcgacc gcgtgttcac ccgcatcgac cagtcgatcg
      181 cgatggcggc gatctggacc gcctaccacc tcaaggtcaa ggcgatcgcc tcgctcaccc
      241 agaccggctc gaccgcgctg tggatgagcc gcctgatcgc cggcgtgccg atctacgcgc
      301 tcacccccga ggtctcggcg cgcaaccaga tgacgctcta ccgcgaggtg catccgctgc
      361 tgatgagcca gacccaccag gaccgcgacg tgctgctgtg ggaggccgag caggtgctgc
      421 tcgagcaggg cgtggtcgac tacggcgacc tcatcgtgct caccatcggc gagccgatcg
      481 gcagctcggg cggcaccaac acgctcaaga tcgtccgggt gggagaacac caccgccccg
      541 gcacgctcga cgaccccgtc tgaatacgct tccgcgacgg gagacacggc cagcgtcccc
      601 acgcacacgc taaaataacg ttttcgatcg tccggccgcc ctgcacggca gccatttccg
      661 gagagattcc atgcccctcg tttccatgcg ccagctgctc gaccacgccg ccgaacacag
      721 ctacggcctg cccgccttca acgtgaacaa cctcgaacag gtgcaggcga tcatggaagc
      781 ggccgccgag tgcgacgccc cggtgatcat gcaggcctcg gccggcgcgc gtaagtacgc
      841 cggcgaagcc ttcctgcgcc acctcatcga cgccgcgatc gaggcgtatc cgcacatccc
      901 ggtggtcatg caccaggacc atggccagtc gccggcgatc tgcatgggcg cgatccgctc
      961 gggcttctcg agcgtgatga tggacggctc gctgctggaa gacggcaaga cgccctcgtc
     1021 ctacgagtac aacatcgccg tcacccgcga ggtggtgaag ttctcgcacg ccatcggcgt
     1081 cagcgtcgag gccgagctcg gctgcctcgg ctcgctcgag accggccagg ccggcgagga
     1141 agacggcgtc ggcgccgagg gcacgctgga tcacagccag atgctcaccg accccgacca
     1201 ggccgccgac ttcgtcaagc agaccgactg cgacgcgctc gcgatcgcga tcggcaccag
     1261 ccacggcgcc tacaagttca cccgcaagcc caccggcgac atcctcgcca tcgagcgtgt
     1321 caaggccatc cacgcccgca tccccaacac ccacctggtg atgcacggct cctcctcggt
     1381 gccgcaggag ctcctcgaga tcatccgcca gtacggcggc gacatgaagg agacctacgg
     1441 cgtgccggtc gaggagatcg tccagggcat caagtacggc gtgcgcaaga tcaacatcga
     1501 caccgacatc cgcctcgcca tgaccggcgc gatccgcaag ttcatgttcg agaacccgtc
     1561 gaagttcgac ccgcgcgagt tcaacaagcc cgcgcgcgag gccgccaagc tggtgtgcaa
     1621 ggcgcgctac gaggccttcg gctgcaccgg catggcctcg aagatcaagc ccgtctcgct
     1681 cgacaagatc gccgcgcgct acaaggccgg cgagctgacg cagatcgtgc gctgagccca
     1741 ccgtcgttcg cgcctgtacc gagaaacgcg cccatgaggc gcgtttttca ttggctcgtc
     1801 cttttcgccc gcttcagcac tccatcgccc gcatccgcgc cgcgccctcg gtctgcagga
     1861 agtccagcaa cgcgtcgagc gccggcgtca tcgggcggtc ggtgcgcgag accacgttcc
     1921 actcccggat gaccggcgta tccgccacgt ccagccgcag caggcgaccg ctctccacct
     1981 ccatcgcaaa agtgtggtgc gacaggaagg cgatgcccat gcccgccatc accgcctgct
     2041 tcaacgtctc gttgctgccc agttcgtccg ccgcgagcgg cttgacccca tgcgcgcgca
     2101 ggaagcgctc gaggttgtcg cgcgtgcccg agccctgctc gcgcagcagc aggcgctcgc
     2161 cggtgagcgc ggcgggcggg atgcgcgtgc gcccggcgag gcggtgatcg ggccgcgcca
     2221 cgaatgacag ccggtgcggc gcgaagggga tgcggcgcag atccaggccg cgcggcggct
     2281 ggcccatgat cgcgacatcg cagcgctgct cctgcagcag ggcgcgcaca tgctcgcgat
     2341 tggccacggt gagccggaac gtgatgtccg gaaagcggcg gccgaattcg gccagcaggt
     2401 agggcacgaa atactccgcc gtggtgatcg ccaccacatc cagcgtgccc gccgccacgc
     2461 cgatgcgcgc cttcagctcc acctcggcca gctccagact gtgcagcacc tgccgcgccg
     2521 cgcgcaccag cacctcaccc gccggcgtca gccgcacctc acgccggcca tccaccagca
     2581 cctggccgac gatgcgctcg gcgtcgcgga tctgcatgga gatcgccggc tgggtcaggt
     2641 gcagcagccg cgccgcctgg gtaaagctgg cgctgtcagc gacggcgacc agcgcacgaa
     2701 gctgcttcag ggtcaggcgc tgggcgagtt tcatcagaaa acgtgatctc aaataaacac
     2761 aaaacgtcat tggatcttat tttagcgacc ccttattgtc cagtcaccac tgcttgacac
     2821 accactcgca gcacacaaac ggaaggagac aggacatggg cgccgcagac accccgcagc
     2881 agatcatcga tcccaggaag cgctaccagg ccggcgtgct caagtacgcg cagatgggct
     2941 actggaacgc cgactacgcg ccgaaggaca ccgacgtgct ggctgtcttc cgcatcacgc
     3001 cccaggaggg cgtggatccc atcgaggccg ccgccgcggt ggccggcgaa tcgtccacgg
     3061 cgacctggac ggtggtgtgg accgaccgcc tgaccgcgag cgacatgtac cgcgccaagg
     3121 cctatcgcat cgagccggtg ccgggccagg agggccagta cttctgctgg gtggcctacg
     3181 acctcgacct cttcgaggaa ggctcgatcg ccaacctcac cgcttcgatc atcggcaatg
     3241 tgttcagctt caagccgctc aaggccgcgc gcctcgagga catgcgcctg ccggtggcct
     3301 acgtgaagac cttccgcggc cccccgaccg gcatcgtggt cgagcgcgag cgcctggaaa
     3361 aatacggccg cccgctgctg ggcgcgacga tgaagcccaa gctcggcctc tccggcaaga
     3421 actacggccg cgtcgtctat gaggccctgc gcggcggcct ggacttcacc aaggacgacg
     3481 agaacatcaa ctcgcagccc ttcatgcact ggcgcgaccg cttcctgtac tgcatggaag
     3541 gcgtcaatca ggccgccgcg cagaccggcg aatccaaggg ccactacctc aacatcaccg
     3601 ccggcaccat ggaggagatg tacaagcgcg ccgaattcgc ccgcgacctc ggctcgtgca
     3661 tcgtcatgat cgacctcatc gtgggctgga ccgcgatcca gtcgatcagc aactggtgcc
     3721 gcgacaacga catgatcctg cacatgcacc gcgcgggcca tggcacctac acccggcaga
     3781 agaaccacgg cgtgagcttc cgcgtgatcg ccaagtggct gcgcctggcc ggcgtcgacc
     3841 acctgcacgc cggcaccgcg gtgggcaagc tcgaaggcga cccgatgacg gtgcagggct
     3901 tctacaacgt ctgccgcgac acctacacca agcaggacct gacccgcggc ctgttcttcg
     3961 accaggactg ggccagcacc aagcgcgtga tgccggtggc ctcgggcggc atccatgccg
     4021 gccagatgca ccagctgctg accctgttcg gcgacgaggt ggtgctgcag ttcggcggcg
     4081 gcaccatcgg ccacccgatg ggcatccagg ccggcgccac cgcgaaccgc gtcgcgctcg
     4141 aggccatggt gctcgcccgc aacgagggcc gcgacatcgc caacgaaggc ccgcagatcc
     4201 tcgccgacgc cgccaggtgg tgccagccgc tgcgcgccgc gctcgatacc tggggcgaga
     4261 tcaccttcaa ctacaccagc accgacaccg cggacttcgt gcccaccgcc agcgtggcct
     4321 gaaccaccgc gcccgaggag acaccatcat gcgcatcacc caaggctgct tttccttcct
     4381 gcccgacctc tccgacaagc agatcgcggc gcagatcaac tactgcctgg atcaggactg
     4441 ggcggtcgcc atcgaattca ccgacgaccc gcacccgcgc aacacctact ggaacatgtg
     4501 gggcctgccg atgttcgacc tgcgcgaccc cgcgggcgtc atgggcgagc tcgaggcctg
     4561 ccgcgaggcc aaccccgaga cctacatccg catcaacgcc ttcgactcga ccaagggctg
     4621 ggagacggtg cgcatgtcct tcatcgcgca gcgcccgagc gtggagcccg ggttccgcct
     4681 tgtccgccag gaaacgcagg gccgccagct gcgctacacg atggagagct acgccgtcgg
     4741 ccgcaacccg gaaggcgcgc gctacgcggg ctgagtgcgc tgcgacacgc ctgtccgtgg
     4801 gagcggactc gcccacgacc gatgccctcg agccccgcat ccgcggacaa gcccgctccc
     4861 gcaagctcac ccccccgtca ggagacgaga ccatgaacgc ccccgagcaa gccaccgcca
     4921 tcgacctcgc cgccgagttc cgcgacgccg gcatcggcga agtgctcgag gccctcgagc
     4981 gcgacctcgt cggcctcgcc ccggtcaagc gccgcgtgcg cgagatcgcc gccctgctgc
     5041 tggtcgaccg cgtgcgccag cgcctcgggc tggccaccga gcccccctcg ctgcacatga
     5101 gcttcagcgg caaccccggc accggcaaga ccacggtggc gatgcgcatg gccgagatcc
     5161 tgcaccggct gggctactgc cgccgcggcc acgtggtcgc cgtgacccgc gacgacctcg
     5221 tcggccagta catcggccac accgcgccca agaccaagga agtgctcaag cgcgccatgg
     5281 gcggcgtgct cttcatcgac gaggcctact acctctaccg ccccgagaac gagaaggact
     5341 acggccagga agcgatcgag atcctcttgc aggtgatgga gaaccagcgc gacgacctgg
     5401 tggtgatcct cgccggctac gccgaccgca tggagcgctt cttcgagtcc aaccccggca
     5461 tgaagtcgcg catcgcccac cacgtcgact tccccgacta cagcgacgcc gagctcggcg
     5521 agatcgcccg gcgcatgctc gccggctgga actaccgctt cgacgacgcc gcgcgccgcg
     5581 ccttcgacga gtacatcgtg ctgcgccgga cgcagcccca cttcgccaac gcgcgcagca
     5641 tccgcaacgc gctcgaccgc atgcgcctgc gccaggccct gcgcctgttc gactccggcg
     5701 ccacggtcga cgctggggcg ctcaccacga tcaccgaggc cgacgtgcgc gccagccgcc
     5761 acttccggcc cgacgaggcc gccagccccc agtgacgtgc cgctcgccgg cccgccgcga
     5821 ccgcgacccc gaccgataac gacagacacc gagccggcgc cacgccgggg gagaccagca
     5881 tgttcagcct cgaccgcagc acactcaccg agtacctcat cgagcaccgc cgccacaacc
     5941 ccgaagccac cggcgagttc aacgccctga tcctgcaggt cgcccaggcc tgcaaggcga
     6001 tctcgcgcgc ggtcgcccac ggcgcgctcg ccgacgtgct cggcagccac ggcagcgcca
     6061 acgtgcaggg cgaggaacag aagaagctcg acgtgctcgc cgacgacatc ttcctgcgcg
     6121 ccacgcactg gggcggcgac ctcgccggca tggtctccga ggagaacgag gcccccatcc
     6181 cgctgcccgc cagcgaccag cgcggcaagt acctgctcgc cttcgatccg ctcgacggat
     6241 caagcaacat cgacgtcaac gtcgccgtcg gctccatctt ctccatcctg cgcgcgccca
     6301 cgccgggcga agacgccacg gcggaagact tcctgcagcc cggcaaccgc caggtcgccg
     6361 ccggctacgc catctacggc ccctccacca tgctggtgct gtcggtcggc agcggcgtcg
     6421 ccggcttcac cctcgacccg atcatcggcg agttctacct cacccacccc gacatccgcg
     6481 tgccggcgac cacccgcgag ttcgccatca acacctcgaa cgcgcgcttc tgggagcccc
     6541 cggtgcgccg ctacgtcgac gaatgcctgg ccgggcgcac cggcccgcgc ggcgtcgact
     6601 tcaacatgcg ctggatcgcc tcgctggtcg ccgagaccca ccgcatcctg atgcgcggcg
     6661 gtgtgttcct ctacccgcgc gaccgcaagg acccgacaaa gccaggccgg ctgcgcctgc
     6721 tctacgagtg caacccgatc ggcttcctga tcgagcaggc cggcggacgc gccagcaccg
     6781 gcgtacgccc ggtactcgag gtccggcccg agggcctgca ccagcgcatc ggcttcgtgt
     6841 tcggctcgaa ggatgaggtc gaacgcatcg agcgctacca cagcgagccg gtgatcggcg
     6901 gcgcccagga cgagctgccg ctcttccagc cccgctccct gttccgcgac accgaattca
     6961 ctcaatagcc tgcggggaac accatgtccg aacgtcatcc gatcgtcgcc atcaccggct
     7021 cgtccggcgc cggcaccagc accgtgcagc gcaccttcga ggagatcttc cgccgcgagg
     7081 gggtcaccgc cgcggtcatc gagggcgaca gcttccacgc ctacgaccgc aagaccatgc
     7141 gcgagaagct cgccgcctgc gacctcgacg gcaactgcca gctgagccac ttcggccccg
     7201 aggccaacct gttcggcgaa atcgagaacc tgttccgcag ctacgccgag tccggaacgg
     7261 gcaagcgccg caaatacctg cacagccccg aggaggccga gccctggaag caggaacccg
     7321 gcaccttcac cccgtgggag gagctgccca ccggcaccga cctgatgttc tacgagggtc
     7381 tgcacggcgc cgttcaacac gagaacatcg acgtcgcgcg cttcgtcgat ctgctcatcg
     7441 gcgtggtgcc ggtgatcaac ctcgagtgga tccagaagct caaccgcgac aagagcatgc
     7501 gcggctactc caccgaggcg gtcaccgaca ccatcctgcg ccgcatgcac gactacgtgc
     7561 attacatctg cccgcagttc gcgcgcacgc atgtgaactt ccagcgcgtg ccgatggtgg
     7621 acacctccaa ccccttcatc gcgcgcgcca tccccaccgc cgacgaatcc atggtggtga
     7681 tccgcttcgc caaccccaag ggcatcgact tcccctacct gctcaacatg atcaacgaca
     7741 gcttcatgag ccgcgccaac accatcgtgg tgccgggcgg aaagatggag ctggcgatgc
     7801 agctgatctt cacccccttc atctggcgcc tgatggaccg ccgccgcaag gcgctggcgc
     7861 aatgagaacc aaacgcctgc cgccgcgccc caggaacgtc cggcagcaga aaggtctttc
     7921 acggccgttg tgcaccaccc acgtccagcg gagagcaggc ggtgttcctt aagcagcctg
     7981 cggaactcgc cctgcgggct cggacagtcc tcggctgctc cagaaacgcc ccatacgcca
     8041 cgctggccgt gccgactggc cgacggccat aagcagtttc atttgtgatt ggagaggttc
     8101 cgatgaacat gcgactcacc caggcgccga tcgacaccct gtgcgccaac gcgctgcgct
     8161 ttctcgccat tgacgccgtc gaggccgcca agtccggcca ccccggcatg cccatgggca
     8221 tggccgagat tgccgtcgcg ctgtggacgc ggcacctgaa gcacgacccg gcggaccctg
     8281 cctgggccga ccgcgaccgc ttcgtgctct ccaacggcca cggctcgatg ctgctctacg
     8341 ccctgctcca cctcagcggc tacgagctgc cgctcgacga gctcaaacgc ttccgccagc
     8401 tcgacagccg cacccccggc caccccgagg tcggccacac gcccggcgtc gagaccacca
     8461 ccggcccgct cggccagggc ctgaccaacg ccgtgggcat ggcgctcgcc gagaagctgc
     8521 tcgctgccga gttcaatcgc cccggccacc ccctcgtcga tcaccgcacc tgggtcttcc
     8581 tcggcgacgg ctgcctgatg gaaggcatca gccacgaggc cgcgagcttc gccggcgtgc
     8641 agcggctctc caaattgatc tgcttctggg acgacaacgg catctcgatc gacggcgacg
     8701 tctccggctg gttcgccgac gacacgccgg cacgcttccg cgcctatggc tggaacgtgg
     8761 tcgaggcggt ggacggccac gacgtcgccg ccgtcgatcg cgccatccag atggccctgg
     8821 gcaacgccga ggccgacacc ggcccgacgc tgatctgctg ccgcaccgac atcggccatg
     8881 gcagccccgg gcgcgcgggc acggccgatg tgcacggcgc ccccctcggt gccggcgaga
     8941 tcaccgccac gcgcggcgca ctcgactggc cacacctacc cttcgagatc cccggcgagg
     9001 tccgcgccgc cttcgacgcg cgcgcccgcg gcgcggcgca gcacgacgaa tggcgtgccc
     9061 ggctcgacgc ctacacccag gccttcccgg aagaggccga ggagttttgc cgccgcatgg
     9121 ccggcgcgct gccggtgagc ttcccggtac tgtccaacgc catcctgcgc ggcgtggaca
     9181 aggaggccgc cgagctcgcc acccgcaagg ccagccagca ggccatcggc cgcctggcgc
     9241 gcgcgctgcc cgagctgctc ggcggctcgg ccgacctcac ccactccaac ctcaccgact
     9301 ggccgggctg cggcgcggtg cgcgcggatg cccccgggcg ccacatcaac tggggcgtgc
     9361 gcgaattcgg catggccgcg gccttgaacg gcatcgcgct gcacggcggc ttcatcccct
     9421 tcggcgccac cttcctggtg ttctcggact acgcccgcaa cgccatccgc atgagcgcgc
     9481 tgatgaagca gcgcgtggtg tacgtgatga cgcacgactc gatcggcctc ggtgaggacg
     9541 gccccaccca ccagccggtc gagcacatcc ccagcctgcg cctgatcccc gggctggacg
     9601 tgtggcggcc gtgcgatgcg gtcgagaccc aggccgcctg gaacgccgcg gtcgcgcgcc
     9661 gcgacggccc caccctgctc gccctgtcgc gccagaacct gccgcaccag gcgcgcgacg
     9721 aggtgcagat ccaggccatc ctgcgcggcg gctatgtgct cgccgatgcc gacgcgcctg
     9781 cgctcgtcat catcgccacc ggctcggagg tggcgctggc gatggcggcg cgcgcggcgc
     9841 tggccgccga gggggtcggc gtgcgcgtgg tttccatgcc ctgcaccacg ctcttcgacc
     9901 gccagaccga cgaatggcgg cgcagcgtgc tgccggccgg cgtaccccgc ctggtgatcg
     9961 aggccgcacg cggcgacgcc tggtggcgaa ccatcgccag cgacggcggc cgcggcggcg
    10021 acgtgatcgg catggagtgc ttcggcgaat ccgctcccgc cggcgccctg ctggcgcgct
    10081 tcggcttcac cccggcagcg gtgctcgagc gcgcccgtgc gctcctcgcc gccacgaacc
    10141 agcctggtcc cgcggcgatg cacggcaccg cacccttgcc cgaaacccgc aagatctcga
    10201 acgggagctg aacccatgaa cttcctgcgc ctcgccgaac tcgacctcgc cggaaaacgc
    10261 gtcttcatcc gcgccgactt caatgtcccc ttcaacgccg acggcacgct gtcggacgac
    10321 acccgcatcc gcgccacgct gccggcgatc caccactgcc tggaggccgg cgcggcggtg
    10381 atggtcacct cgcacctggg ccgccccacc gagggcgcgc tcaccgcagc cgactcgctg
    10441 gcaccggtcg ccgcgaccct gtccgacctc ctcggccgcc cggtgccgct gatccgcgac
    10501 tggacggggg gcggcttcac ggtacgcccg ggcgaggtcg tgctgctcga gaattgccgc
    10561 ggcaacgtcg gcgagaaggt cgacgatccc cgcctcgccg cccgcatcgc gagcttcatc
    10621 gacgtgtatg tgaacgacgc cttcggcacc gcccaccgca gcgaatgcac gctgcacgcg
    10681 ctcgcgctcg ccgccccggt cgcctgcgcc ggcccgctga tgaccgccga gctcgacgcg
    10741 ctgggccgcg cgctcgccca gcccgcgcgc ccgctcgccg ccatcgtcgc cggctccaag
    10801 gtgtcgacca agctcaccat cctcgagagc ctggccgaca aggtcgatgt gctcgtcgtg
    10861 ggcggcggca tcgccaacac cttcctcgcc gcgcgcggct gcgaggtcgg cgcctcgctg
    10921 cacgagcccg acctgctcga ggccgcccgc cgcgtcgagc gccggctggc cgagcgcggc
    10981 ggcgtggtgt ggctgcccga ggacgtggtg gtggccgacc gcttcgccgc cgacgccgac
    11041 acccgcatct gcgacgccga atccgtgccg ccgggctgga tgatcctcga catcggcccg
    11101 aacagccgcg actcgctcgc cggcgtgctc gcgcgcgccg gcaccatcgt atggaacggc
    11161 ccggtgggcg tgttcgagat ggacgccttc gccgccggca cgcgtgcgct cgccgaggcc
    11221 atcgccgcca gccccgccta cagcatcgcc ggcggcggcg acacgctggc cgcgatcgcg
    11281 cgcttcggcg tgggcgggcg catcgactac atctccaccg gcggcggcgc cttcctcgaa
    11341 ttcctcgaag gccgcgagct gccggcggtc accgccctgc gcgcccgcgc ccgcccggca
    11401 agccgacgtg tcgagccggt gccgcagttc gagcacgaac ccgaactcac ctgaccttcc
    11461 tgcggagacc tcccatggcc atgatcgccc tgcgccagct gctcgaccac gccgccgagc
    11521 acgactacgg cgtgcccgcc ttcaacatca acaacatgga gcagatccag gcgatcatgc
    11581 tcgccgccga ggccacggac agcccggtca tcctgcaggc ctcggccggc gcgcgcggct
    11641 acgccggcga ggccttcctg aagaagatgg tcgaggctgc ggtcgagcag tggcccgacc
    11701 tcccgatctg cctgcaccag gaccacggcg ccagcccggc ggtgtgccag cagtcgatcc
    11761 gcagcggctt caccagcgtg atgatggacg ggtcgctgcg cgaggacatg aagacgccgg
    11821 cgagctacga ctacaacgtg gacgtcaccc gccgcgtggt cgagatggcg cacgcggtgg
    11881 gcgtgtcggt ggagggcgag ctcggctgcc tgggctcgct cgagaccggc caggccggcg
    11941 aggaggacgg cgtcggcgcc gaaggcacgc tggaccacag ccagatgctg accgacccgg
    12001 cggaggccgc cgacttcgtc gccgccaccg gggtcgacgc gctcgcggtg gcgatcggca
    12061 ccagccacgg cgcctacaag ttcacccgcc cgcccaccgg cgacatcctc gccatcgagc
    12121 gcatcgccgc catccacgcg cgcatcccga aaacgcacct cgtcatgcac ggctcgagca
    12181 gcgtgccgca ggagtggctc gccatcatcc gcgagcacgg cggcgagatc ggcgagacct
    12241 acggcgtgcc ggtcgaggcc atcgtgcagg gcatccgcag cggcgtgcgc aaggtcaaca
    12301 tcgacaccga cctgcgcctg gcgatgagcg gtgcgatgcg ccggctgatg gcgaccgatc
    12361 gcaaggagtt cgacccgcgc aagttcttca aggccgcccg cgacgccgcg cgcgacatct
    12421 gccgcgagcg cttcgaggcc ttcggctgcg ccggccgggc cagccgcatc aagccgctgg
    12481 cactggagaa gctcgcccgg cgctacgccg cgcatcgcgg ctgagcgcac gctctacaag
    12541 agcgctgcca atccgcctgc cgctcgagca ctccctgccc tcgggcattc ggctcgctcc
    12601 ccctcgggga agcgggcctt ttttcgacgc gcccccgcgg ccggcggctt gccgcttgtc
    12661 agtgcgtgag gacgtgggca agaatggtcc cggaaagcca gcctccgggc gcatgcgccc
    12721 gccctcgacc acgccccccg ccatcatgtc ctccctgttc gaacagcatc ccctgcgcca
    12781 ggtcctcaac gacgaggtgc atgcgcgccc gccggtgccg ctggacaccc cggaattcgt
    12841 cacctacctg gccttcctgc accatgaagg cagcgccggg cgcgaggcgg accacctcgc
    12901 cgcgctggcc gggcagctcg gccagccggc accgaacatc gaatccggcc acgtgctgct
    12961 cgaggccgag ggcttccggc tgaagtggga gcgccacaac gagttctcca gctactgctt
    13021 cttccgccgc atcgaacccg gcgacagccc cgacgactac gccctgctcc acgttcccgc
    13081 ggcgtggcgc aaggccatcc ccggcctgct gatcgccgcc acccacatcg agctgcgcag
    13141 cattgccgag gtgccgctcg aatcggtgct gcaccagcag tcgcgccatg gccaggccct
    13201 ggtggcctcg ggcgtgtcgg acggtgccgg ctgggtgctc accgacttcc acctgcacga
    13261 cggcttctcg cacttcctgc tgctcgacaa cggcttcacc ccgcgccagg ccggccgcat
    13321 cgcccagcgc ctggtcgaga tcgagaccta ccgcgtgatg gcgctgctcg ccttcccggt
    13381 ggccaaggac accggccgcc tcgtctcgcg cgccgaggac gagctcgccg acctcatgga
    13441 cggcatgggc cagtcgcgca gcgccgagga cgaccgcgcc gtgctcgccc gcctgtcgcg
    13501 cctggccgcc gaggtcgagc gctcggtcgc acgcaccacc ttccgcttcg gcgccgccgg
    13561 cgcctactac cgcctcgtgc gccagcgcat cgacgacctg cgcgaagatc gcctgcccgg
    13621 cttctcgccg atcggcgagt tcatggaccg ccgcctcgtc cccgcgatcg acacctgcac
    13681 ctcgatcgcg cgccgccagg acgacctctc cggccgcatc gcgcgcaact cgcagctgct
    13741 gcgcacccgc gtcgacatcg agatcgagcg ccagaaccag gagctgctcg cgcagatgaa
    13801 ccgccgcgcc aagatccagc tccacctgca ggagacggtc gagggcctgt cggtggtggc
    13861 gatcacctac tacgcttcgc agctggtgaa ttacgtctcc aagggcgcca agcacctgat
    13921 cgagccgctc acgcccgagg tgctgaccgc ggtctccatc ccggtcatcg ccggcgtcgt
    13981 ctacatgggg ctgcggcgga tgcgcaagct gctgggcgcg gaagaggacg gccaggcgca
    14041 cccctgacgg agccggcgcc cgcgcccccg cggcggacgg gccgatgctc aagtcagcac
    14101 ggcgtcgagc ggacggcgca gcgatcgggg catcgccggc cctctcccga accggatcac
    14161 cagatccggc cggccgtacg cgataccgag gaaggcgccg aaggcggggc gcagcgcggc
    14221 gagttcgacg ggctggttga gatgtgcgct gcggacgccc agcgcgctcg cctgcagcgc
    14281 gaagcgctgg aagcaacgcc ccgcctcgat ccagtgcgcg cggtcgtcgc gctcggagac
    14341 gaacacggcg atcccggcgg cgctgcggac gtgccgcgca tacttgtcgt tctcggcctg
    14401 ctcggtgaag aaggcatcga acagcaggct gccgagccag gctggggcgg tggggtttcc
    14461 ggacgcgcct gcgaacaggc cgtcgcccag gcgcgcggcg tcgccgccgt tgaagcggat
    14521 ccacgccttg agctcgcgca cgaatgcggg atcgcgcatc tgcgccgtgt tgccggcgac
    14581 gacgaactcg agcacgcgct ccaggtccgg cgccgcggtg agcaggcgca cacgcacgcc
    14641 cctgcccgtg ccggccgcct cgagcagccg cagctccgcg ttcgagagcg gccgtgagtc
    14701 gaactcgccc cgggtcgact ggcgcagcgg gatggcctcg aacaaggcgc ttcgccgact
    14761 cgccgcaggc gccagcgcgc agagcacggg gccgcctccc tcgccggccg gggcggtctc
    14821 atcggcctcg gtgacgagcg cgggctcgca gtgcaatccc atcgccggcg ccgcctgcac
    14881 gaggttctct gcggcgcagc ccaggctgac gaagaggtgg tggtcgtccg gatccacgac
    14941 cgggcagcgc cgcgcgtagt cgggaaagat ggaaaccgcc cgctcggcca gcgcgaactt
    15001 ccagcactgc gtgttgtggc tggacggcgc gagggtggcg tagcgcacga gctcgcgcag
    15061 caccgcgcgc gcgtccccct gcaagggctc gccatggcgc caggtcgaat ccgccgccgc
    15121 ctcgtacgcc gctgcgccgc ggacttggga caggtagccg gccccgcccg ccacccccag
    15181 cccggcgagc gccgcagcgc cgatgaatcg tcttctctcc atgccccgcc tccgtcctac
    15241 cacccggtct ccagggcagt ctagacgcgc ctgcgggctg gcgcgaggcg gcccgcgccg
    15301 cgtcggacgc gaagccgtgc acgcccgtgc gcgcctgcgt ggaaccgcac cccagcgccg
    15361 cggtctccac tgcatgccca ccgccggagc cgcaagcatg tcctcccatt ccggactccg
    15421 ccgccgtctc gtcctcggcg gcagcgccac gctgctctcc gcgccgctcg cggcggcgca
    15481 gcgcgcgctg acgccgagcc agatgctcgg ccccttctac ccggtcacgc cgccgctgca
    15541 ccaggacaac gacctcaccc gggtcgaagg ccgcagcggt cgcgccgccg gacagatcgt
    15601 cgacctctcg ggccgcgtgc tcgacttcga cggccgcccg ctggccggcg tgcgcgtgga
    15661 gatctggcag tgcgacgcca acggccgcta ccgccacccg cgcgaccccg gcgacgtcga
    15721 ggaagacccg aacttccagg gcttcggcca caccgtcacc gacgccgacg ggcactatcg
    15781 cttccgcacc atccgcccgg tgccctaccc ggggcgcacg ccgcacatcc acgccgcggt
    15841 gatccaggaa ggcgcccgcc ccttcgtcac tcagatctac gtcgccggcg agccgctcaa
    15901 cctgcgcgac ggactattca tgcgtgtccc cgaggcgctg cgtccgctgc tgctcgccga
    15961 cttcgtcccg gcgaacgacc cggtcgcgac gctctcggcc tcgttcgact tcgtgctggc
    16021 gccggtgctg gcggggctat tcgaggccca cacggtctga atccgcgcga aataggggac
    16081 agaccacgat ttcgcggcgg ctcagccgct gcagcgcggc atggccccaa aatcgtggtc
    16141 tgtcctctat taccagacgg cgcatcgctc caggctgagg taggcctcga cctcatccag
    16201 tcccccgagg gagacgaatt cggaggccga aagaatgtcc tcgaaccttg cggtcaccat
    16261 gatttttcct cgctccgtgc tccggacctg ggaccgattt aaatccgccc cgttctcccg
    16321 tcctgcactc tggcaaggcc gccgcaggca tggccgggag tggaagcaag gcggtacgcg
    16381 taaaccggtg cgtcgcaacc cgcctcccct ataatcccgg ctttgccagc aacccgaggc
    16441 cccaccgtgg cgacgcccat cttcgagact tccatccaga gcctgccgct gctcggccgc
    16501 ggcaaggtgc gcgacatcta cgccgtcgat gccgacaagc tgctgatcgt gaccagcgat
    16561 cgcctgtcgg ccttcgacgt gatcctgccc gacccgatcc ccgacaaggg ccgcgtgctg
    16621 gtggcgctgg cgaacttctg gttcgaccgg ctcggccaca tcctgcccaa ccagctcacc
    16681 ggcatcgatc ccgagaccgt ggtcgccgcc gacgagcgcg agcaggtgcg cggccgcgcg
    16741 ctggtggtca agcgcctcaa gccgctgccg atcgaggcgg tggtgcgcgg ctacgtgatc
    16801 ggctcgggct ggaaggacta ccaggccacc ggcgccatct gcggcatcgc gctgccggcg
    16861 ggcctgcagc aggccgccaa gctgccggcg ccgatcttca cgccttcgtc caaggccgac
    16921 atgggcgagc acgacgagaa catctcgttc gagcaggcgc aggcgcgctg cgaggcgctg
    16981 atgaaggacg cgctcgccgg caccggcaag accggcgccc agctcgccga agaggcgcgc
    17041 gccgcggcga tcgcgctgta ttccgaggcg gccgagttcg ccgcgacccg cggcatcctc
    17101 atcgccgaca ccaagttcga gttcggcatc gacgccgccg gcacgctgca cctgatcgac
    17161 gaggcgctga cccccgactc ctcgcgcttc tggccggcgg acggctaccg cgagggcatc
    17221 agcccgccgt ccttcgacaa gcagtacgtg cgcgactacc tggagacgct ggactggaac
    17281 aagaccgcgc ccggcccgaa gctgccggcc cacgtcatcg agcacaccgc cgccaagtac
    17341 cgtgaggcct acgagcgcct gaccggccgc aagctggact gatcgcgcct ctcgccgcat
    17401 ccccagacaa ggggcgcccc accggcgccc cttttttccg cctccagcct cccgccccat
    17461 tgccaatccc tatcgaccaa ttccaattct catcgacgaa ccattcccat cctcttcgat
    17521 catagatcgc gtgacacctg catcctgccc ggctcggccc cgcggtcccc ggagcccgca
    17581 ggcgtccttc ccgatccgca acgaggagtg aaagatggac aagccctacg gttcgctcga
    17641 gcagcacttc gacctgccca agatccgcac ggtcggccac gaccgtccgc tgcagtggct
    17701 acgcgccggc tggcgcgacc tgcgcgagaa cctcggcgcc agcctggcct acggcatcct
    17761 cctgtcggcg atcggctacg cgatcctggc ctatgccgcg gatcggccct atctcttcat
    17821 cgccgcgatc tccggcttca tgctgatcgg cccgctcgcc gccgccggcc tctacgagct
    17881 ctcgcgccgc agtgaagaag gcgagcgcat cggtttcctc ggctcgctgc gcgggctggc
    17941 gcgcaacgcc gacagcctgg ctttcttcgg cgccttcctg gcgatcgcgc tgctcgcctg
    18001 ggagcgcctg tcggcgatcc tgttcgcgct gttctaccgc ggcgacgtgg acaacgtgac
    18061 caacttcgtc gccggcgtcc tcgccgccaa cgacaacctg tacttcgtct tcgcctacct
    18121 gatggtgggc gcggtgctcg cgctggtggt gttctcgctg tcggcgatcg cgattccgat
    18181 gctgctcgac cgcgacaccg acgcctttac cgcggcaatg accagcctgc gcgcggttca
    18241 ggtcaacttc gacaccatgg cgctgtgggc gctgctgctg gtggcgatga tcggcatcgg
    18301 cttcgccacc atgatgatcg gcatggtgat cctgctgcca ctcgccggcc acgccacctg
    18361 gcacgcctat cgcgagctgg tgcgctgagg gcctggagcc ccctcgaagc ggcgggtgca
    18421 gacgcccgcc gcgcgctttt gcggcagaat agccgcctct cgtccggccg cgccggaccg
    18481 caacgacaag gtcgaacatg caacaaggca cccgcccctc ccccgccaat cccctgctcg
    18541 acttcgccgg catgccgcgc ttcgctgaca tccggcccga gcacgtcgag cccgcgatcc
    18601 gcggcctcat cgacgagaac cgcgcgctca tcgagcgcct caccgccgac cccgccaccc
    18661 cgagctggga ccgcttcgtg gcgccgatgg aagaggccgg cgagcgcctc ggccgcgcct
    18721 ggggcgtggt cggccacctg cacagcgtgt tcgacgtgcc cgagtggcgc gaggcctaca
    18781 acgccatgct gcccgagatc tcgcgcttct acgccgaggt cgggcagaac ctgacgctgt
    18841 tcgagaaata caaggcgctg cacgacagcc ccgagttcgc caccctgtcg gcggtgcgcc
    18901 agcgcatcct cgaccacgcc ctgcgcgact tccgcctctc cggcgccgag ctgcccgacg
    18961 aacagaagcc gcgcttccag gccatccagg aagagcagtc ccagctcgcc gccaagttct
    19021 ccgagaacct gctcgacgcc accaacgcgc acgccgagtg gatcgccgac gaggccggcc
    19081 tttcggggat tcccgaggat gcacgcgagg ccgcccgcgc cgccgccgaa gccgaaggca
    19141 agccgggctg gaagttcacc ctgcagatgc cctcctacct gccggtgctg cagtacgccg
    19201 atgaccgcga gctgcgtgca cgcatgtacc gcgcctacgc cacccgcgcc tccgagctcg
    19261 gcgacccgga gctcgacaac ggcccgctga tcggccgcat cctcgcgctg cgccatgaag
    19321 aggcgcgcat gctcggctac cgcaacttcg ccgaggtctc gctggtgccc aagatggccg
    19381 acacgccgga gcaggtgctc ggcttcctgc acgacctcgc cgccaaggcc aagcccttcg
    19441 ccgagaagga cctgcaggag ctgaaggtct tcgccaaggc cgagctgggg ctggacacgc
    19501 ttgagccctg ggacgtggcc tacgcctcgg agaagctgcg cgaacagcgc tacgcctact
    19561 ccgaccagga ggtgaagcag tacttccccg agcccaaggt gctcgacggc ctgttcggcg
    19621 tgatccgcgc gctgtatcgc gtcgacatcc tccccgacga ggcgccgagc tgggaccccg
    19681 atgtgcgctt cttccgcatc gagaaggaca gcgcgaacgg cccggaactc gtcggccact
    19741 tctacctcga cctgcacgcg cgcagcacca agcgcggcgg cgcgtggatg gactcggcgc
    19801 gcagccgcca ccgcaacacc tggggtagcg acacgccggt ggcctacctg gtgtgcaact
    19861 tccccggccc ggtcggcgag ggtacgaaga agcggcccgc caccttcacc cacgacgacg
    19921 tgctcaccct gttccacgag tgcggccacg gcctgcacca cctgctcacc caggtggacg
    19981 agctcgcggt gtcgggcatc cacggcgtgg agtgggacgc ggtcgagctg cccagccagt
    20041 tcatggagaa cttctgctgg gagtgggacg tgctgcaggg catgaccgcg catgtcgaca
    20101 ccggcgagcc gctgccgcgc gcgctctacg acaagatgat cgccgcgaag aacttccaga
    20161 gcggcatgca gaccgtacgc cagctcgagt tctcgatgtt cgacctgcgt ctgcacggcg
    20221 aggtggacgc gtcctcgggt cccgtcccga tcgagcgcgt gatggccctg ctcgacgagg
    20281 tccgcaagga ggtcgcggtg atgatcccgc ccgcctggca ccgcttcccg cacagcttct
    20341 cgcacatctt cgccggcggc tacgcggccg gctactacag ctacaagtgg gccgaggtgc
    20401 tgtcggccga cgccttcgag gccttcgagg aagccggcgc gggcaagggc agcctgctcg
    20461 accccgagac cggggagcgc ttctggcgcg agatcctggc agtgggcggc agccgcccgg
    20521 cgctggattc gttcaaggcc ttccgcggcc gcgaacctaa agtagatgcg ctgctgcgcc
    20581 acagcgggat ggtggcgcag gcctgaagtt cggaatcgaa ggccgagcac accgatccga
    20641 taaaggcagg ctcttatcgc aatttgctat taatcgcaaa ttgcgataac gttgccccga
    20701 tgaagctgat ctcgaacaag gcgctgcgag acttctctgc gtgccatgct gacgccgagt
    20761 gcccactgca ggcctttcgg cagctgatcg agaaaggcca ctatccgcac ttcgctgccc
    20821 tgcgcgccac gttgcgtggt gtcgacaagg tcggcgagcg ctatgtgttc aacatcggcg
    20881 gcaacaagta tcgcctgatc gcggccatcg cctttacccc gcagctgctc tgggtgaagg
    20941 ccgtgctcac gcacgcagac tacgacgaag gagactggaa atgagcgtca cggacgtcct
    21001 cgccccttgg gccgccatca atgacgcgct tggcttgtcc gcgccgatcc gcgacgaggc
    21061 gcattacgcc gaattgctgg ccttcgtcga cgaagccttc gaacagttcg gcggaaacga
    21121 cgagcacccg atcttcggcc tggtctcgat cgtggccgac cggatccgcg agtacgaggc
    21181 gcgcgtccac ccctggccgg aactgccgcc gtccgagttg ctgcgcgagt tgatggccga
    21241 gcacggcatc cgccagagcg acctgcccga ggtcggtacg cagtcggtcg tgtccgaggt
    21301 cctggcgggc aagcgcgggc tcaatctgcg tcaggtcaag gccttgtcgg tacgcttcag
    21361 ggttccgatg gaagtgttcg cagcctgatg cggatggctt cgaggatgct cggggcgcca
    21421 tttttctcca ttgcccttcg gcatgcccct cgggtctggt gaccagatcg ccccctcccg
    21481 ttcgataaca aaaggcttgc atgaaaatcg ccacctggaa cgtcaactcc ctgaaggtcc
    21541 gcctgcccca cgtcctcgac tggctggccg ccaacaagcc cgacgcgctc tgcctgcagg
    21601 agctcaagct cgaggacaag gccttcccgg tcgccgatct cgaggccgcc ggctaccacg
    21661 ccgtcttcat cggccagaag acctacaacg gcgtcgccat cctgagccca cagccgatcg
    21721 acgaggccag cgtggtgcgc aacatccccg gcttcgagga cgagcagaag cgcatcatcg
    21781 ccgccaccat cgatagcgtg cgcgtggtgt gcggctactt tcccaacggc caggcggtgg
    21841 gctcggacaa gttcgagtac aagctgcgct ggctcgccgc gctgaccgaa tggctgcgcg
    21901 aggaactcaa gacgcacgag cgcctggtgc tggccggtga cttcaacatc gcccccgaag
    21961 accgcgacgc ccaccccgac tggaaggacg agatccacgt gtcggcgccc gagcgcgccg
    22021 ccttccgcgc gctgcaggaa ctcggcctga tcgacgcctt ccgcctcttc gagcagcccg
    22081 agcgcgcgtt ctcgtggtgg gactaccgga tgatggcctt ccgacgcaac ttcggcctgc
    22141 gcatcgacca cctgctggtg tcgcccgcgc tgcgcgaggc ctgccgcagc tgcagcgtcg
    22201 acaaggagcc gcgccggctg gagcgcccct cggaccacgc accggtggtg ctggaactgg
    22261 cctgaaacga tgagcccgag cctttccccg accgacacga cgcagctgga tgcccgctac
    22321 ccggtgctgg ccgacctttc ggcgccggcg cgcacccgcc tgctgcacag cgcgcagtgg
    22381 atgcgcgtgc ctgcgggcgc gatgctcttc gacgaccgcc aggcctgcga gggcttcccc
    22441 ttcgtggtcg agggctcggt acgggtgagc aagtgcgcgc cgagcgggcg cgagctgccg
    22501 ctctaccgtg tcggcccggg cgagacctgc atcatctcct cgtcctgcct gctcggccac
    22561 gaggactaca acgcacgcgg cgtcaccgag tccgacaccc tgctgatgct gctgccgaag
    22621 gccgtgttcg acgagatgat gggcgagcgc cccttccgcg acttcgtctt ccacctcttc
    22681 gccgagcgta tcgccgacct gatgcaactg atcgaggagg tcgccttccg caagctcgac
    22741 cagcgcctcg cggccctgct gctggggaag ggccgggtac tccacgtcac ccaccagcaa
    22801 ctcgccgacg agctcggcag cgtgcgcgag atcgtcagcc gcctgctcaa gagcttcgcc
    22861 gagcaaggcc tggtgaagct cgcacgcgag caggtcgaga tcatcgaccc ctccgggctg
    22921 cgccgcatgg cctccgaggg caagggcgcg gcctgagaca ccggctcccg gggcgcccgc
    22981 tcgggcacgg atgagcgtag catttcgggc cggacgcggg ctgtgtaacc tcggttacag
    23041 accgcagccg gccgcgcgtg ctccaatgcg gccactcacc tcatccgatc caaggagaac
    23101 agacatgaaa acgaacgttg gtggcgccga caagatcctt cgcatcgtgg ccggtatcgc
    23161 gctgctcgcc tgggcggtgt tcggcggccc ggtgtgggcc tggatcggca tcgtcccgct
    23221 cgccaccggc ctgctcggct ggtgcccggc ctacacgatg ctcggcatga acacctgccc
    23281 gctcagcaag aagtaagcga gcccccacga aaaagccggc acccgccggc tttttcacgc
    23341 ctcacgcctc acgccccgcg cactcgttcg cgatcgcgac gtactgctcc accgacagct
    23401 tctcgccacg cagcccgggg tcgatcccca gcgcctgcag cccggtctcg tcgatgaact
    23461 cgcgcaaggt gttgcgcagg gtcttgcggc gctggccgaa ggcggcggcg acgatgcgcc
    23521 cgagcaaggc ctcgtcgcgg gcgccgagct gatcggccgg cagcggggcc atgcgcacga
    23581 tgctcgacat gaccttgggc gccgggcgga aggcgcccgg cggcacgtcg aacagccgcc
    23641 ccatgcggaa gcggtactgc agcatcaccg aaagccgccc atactcctcg gtgcccggct
    23701 cggccaccat gcgcatcacc acctccttct gcagcatgaa ggtcatgtcc ctgacctggt
    23761 cggcgaagcc ggcgaggtgg aacaggatgg gggtggagat gttgtagggc aggttgccga
    23821 cgatgcgcag gctgcgctca ccgcccccct cgacaccggc gcaaaggctg gcgaagtcga
    23881 acttcagcgc atcgccctca tgcaccgtca gttgctcggc ggtgtagcgc tcgtgcaggc
    23941 gggcgatgag gtcgcggtcg atctcgacca cgtgcaggtg gccgaggcgc tcgatcaggg
    24001 ggtcggtcat cgcccccagg ccggggccga tctcgaccat gagttcgccc ggctgggggc
    24061 ggatgccgtc gatgatcttg cggatgatgt tggggtcgga gaggaaattc tggccgaagc
    24121 gcttgcgcgc gcgatggccg tcggtgtcga agtcgtgcat gggagtcctt tcgccggggg
    24181 cggcccggcc tggcttcgcc gcgctcaggc ggcggcgcgc gcctgcgtca tcgcgatcgc
    24241 gagctcgagc gcggcgaaca ggctgcccgg gtcggcgcgg ccgctgccgg cgaggtcgag
    24301 cgcggtgccg tgatctactg aggtgcggat gatgggcagg ccgagcgtga cattgacgcc
    24361 gccgccgaag ctggcgtgct tgagcaccgg caggccctgg tcgtggtaca tggccagcac
    24421 cgcgtcgccc tgcgccagcg tgtgcggcac gaacagggtg tcggcgggca gcgggccgac
    24481 cagctgcatg ccctcggcac gcaggcgctc gagcaccggg atgatgacgt cgatctcctc
    24541 gcgccccatg tgcccgccct cgcccgcgtg cgggttgagg ccggcgacca ggatgcgcgg
    24601 cgcagccagg ccgaagtggc ggcgcaggtc ggcgtgcagg atgcggaggg tgtcctccag
    24661 cacctgcggc gtgatcgccg ccggcaccgc ggcgagcggc aggtgggtgg tcgccagcgc
    24721 gacgcgcagg ccgccgccca ccagcatcat cactacccgc gacgtcccgg tgtgctcggc
    24781 gaggtattcg gtgtggccgg tgaagggcat ggtctcacgg gcaccgaggc cctcgcagat
    24841 cacgcccttg tgcaccggcg cggtgaccat ggcggcgaat tcgccctgca cgcagccggc
    24901 gatcgcgcgg tcgagcagtc gcagcacgta ggcgccgttg gccgcgtcga gcacccccgg
    24961 ccgggacggc gcggcgagcg gcaggtgcag cacctcgacc gtacccgcgg gcgcaggccg
    25021 cacggggtcg aactcgacca cgcccatggc gctgccgagc gcggcggcgc gcgcacgcat
    25081 gagcccgagg tcggcgagca ccaccgggcg tagcggccag gcacgctcgg ccaggcgcag
    25141 acacagctcg gggccgactc ccgcgggttc gccgctggtg atggcgacga gcccacaccc
    25201 tgcgtgcgcg gccgcgctca atgcccctcc gtcccgtcgt ttcccttccg gcagccgtgc
    25261 gggcgcgctc attcgcgctc gatgcggtag tcgacgtagg tgctgtcgcg cagctggcgc
    25321 acccagtcct cgtaggcctg ctcggccttg cgttcacgca gggcctggcg cgcggcggcg
    25381 cgcttgcgct cgtcggtgac gtcctgcacg cggcgttcca tcacctggat caggtgccag
    25441 ccgaagggcg aacgcaccgg cgcgctgacc gcacccggct gcagcgcgtt catggcacgc
    25501 tcgaactcgg gcacggtgtc gcccgggttg agccagccga gatcgccgcc gcgggcggcg
    25561 gagaggtcgg ccgagctcgc cttggccagc tcggcgaagt cggcgccatt gatcacgcgc
    25621 tcgcggatgc ccagcaggcg ggcctcggcg tcagcgtcgg agagcacctc ggaggtcttg
    25681 atcaggatgt ggcgggcgcg cgtctgctcg agctgttgca cggccatctg gccaccgccg
    25741 cgcacgtcga ccaggcgcac gatgtgcagc ccggcggcgc tgcgcagcac cggcgaggtc
    25801 tcgcccgggc gcatgcggcg caccgcgtcg gcgaacagcg ccggcagacg gtcgagcggg
    25861 cgccagccca ggccgccgcc ctgcaggccg tcgggcgcgt cggagacttc ggcagcgacg
    25921 cgggcgaagt cctcgcccga tcgcagccgc gccatcacct gctcggcacg cctggccacc
    25981 gcctcgacct gctgcggcga ggcgccctcg ggcgtgcgca gcaggatgtg ggcgacggcg
    26041 aactcctggc cggagaaggc gtc
//
LOCUS       DAOTIN010000042        25527 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_2241_length_25527_cov_8.118993, whole genome shotgun sequence.
ACCESSION   DAOTIN010000042 DAOTIN010000000
VERSION     DAOTIN010000042.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 25527)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 25527)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25527
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2241_length_25527_cov_8.118993"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            75..2609
                     /locus_tag="P5537_08315"
     CDS             75..2609
                     /locus_tag="P5537_08315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MASE3 domain-containing protein"
                     /protein_id="HRV78084.1"
                     /translation="MAYFHPIHAHSARRSLGLLAIGLAGLIALWWIPTPPGMAGLAHY
                     LPLHMALETLAIVAAVLVFAVAWLTPERSTAVGMRILACCFLGVAVLDFSHMLSYQGM
                     PDFVTPSSPEKAIDFWFAARLLAATGMLLAALLPWRGCRGVTPGLVLLAVGAYVGLAH
                     ALFLLRPEWAPRTFIAGEGLTAFKVGVEIALTLAFAASAAVLAWRMRKPCAFDAPALL
                     GAAGWMALSELFFTMYADVTDVYNLAGHLYKIGAHYLLFRALVVDGIRAPYAALERSR
                     TELAENSSRLTDEHRRLESILAGTRAGTWEWNVQTGETIFNARWAEMLGYRLEELEPI
                     SIDTWRRFAHPDDLADSDAAIHRHLRGETPYYEHESRMRHRAGHWIRVQDRGALRTLT
                     DKGEPEWMFGTHIDVSDRHRAEQERGEALNRLRQLSDSVPGVLFECRVEADGRMVFPY
                     VGRQVDELIGCRAEDVVDDATAFYARLHPDDRAQVIEEVRRAKDALQDWSASFRVLHP
                     VHGERRIRGEARCQAQPDGAGEWFGYLQDETEAHRNQEWLRLSARVFDASQEGILVTD
                     AEVRIVDANPAMEALTGYARDALLGRNPSVLRSGRHDAAFFAAMYTKLQHDGRWQGEM
                     WNRHRSGEIYVVKVSISTVRDESGRIEHYVAVFTDISKLMAQRDHFSSLANFDALTGL
                     PNRRLLEDRLHQAVGNARRGKHLVVCMLDLDGFKAVNDSAGHAEGDRLLIELAQRMQH
                     ILRAGETLARLGGDEFVLLLVDGDFRPALERVLEVARAPVALCGGGFARVTASIGASA
                     YRHGVEDGAQLLREADHALYRAKRAGRNRWVMFAPEDAAGSETPPA"
     gene            complement(2606..3277)
                     /gene="leuE"
                     /locus_tag="P5537_08320"
     CDS             complement(2606..3277)
                     /gene="leuE"
                     /locus_tag="P5537_08320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004372151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine efflux protein LeuE"
                     /protein_id="HRV78085.1"
                     /translation="MFYGITDLFTFVLGTVFIVLLPGPNSLYVMAAASRWGVRAGYQG
                     AAGIFVGDTILMLLAVTGMASVLRATPELFMVIKYAGAAYLAWVGLALLRGALATWRR
                     GDETAAQVGDGKPDYPPVRSTPHPFRTALLISLMNPKAILFFVSFFIQFVDPAYEHPA
                     LSFVILGVIVQICSVLYLSTLIFAGARLAAQFRRHRRVAAGATAGVGGVFIGFGAKLA
                     TTTLG"
     assembly_gap    3435..3534
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(3861..4763)
                     /locus_tag="P5537_08325"
     CDS             complement(3861..4763)
                     /locus_tag="P5537_08325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004385970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003953 - NAD+ nucleosidase activity
                     [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HRV78086.1"
                     /translation="MSKVFVSYRRDDSAGFAGRLTDALERRFGADSVFRDVDDIAAGA
                     DFGVVIEQALQQVQAVLVVIGPRWLDARDERGRRLDDPGDYVRREVELALASGKPLIP
                     VLVGGATMPAAEALPPTLRGLANRNALALGDAGWRAALARLEAALAQWVEPAAPSKPV
                     RGRRALAAAIAALLLVLGGGWWWLRGADRGPQALVGEWSAEVAYPWNLTLREHYVFTL
                     ADGRIGGSASFLGVPRVLEAVEWDDGRLRFLTRSETVSGDEPPREMGQLYEVWREGET
                     LRVRLQIRRSHSVDAPLEFVAQRQ"
     assembly_gap    4885..4984
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(5034..6305)
                     /locus_tag="P5537_08330"
     CDS             complement(5034..6305)
                     /locus_tag="P5537_08330"
                     /EC_number="3.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0008984 - protein-glutamate methylesterase
                     activity [Evidence IEA];
                     GO_function: GO:0050568 - protein-glutamine glutaminase
                     activity [Evidence IEA];
                     GO_process: GO:0006482 - protein demethylation [Evidence
                     IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0018277 - protein deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis response regulator protein-glutamate
                     methylesterase"
                     /protein_id="HRV78087.1"
                     /translation="MTAPIRVLVVDDSAVVRQVMSEILSAAPGIEVVGTASDPIFAMA
                     RMRRDWPDVITLDVEMPRMDGISFLRQLMAERPTPVIVCSTLTSRGAETTMQALAAGA
                     VSIIAKPTLGLKGFLNDSAQELVAAVRAAARANLRALRAGAGVGLGGVGGRAGAGAEV
                     ESAAAAGSGFGVVPARGLAGAGPGGPRASAGTASGSGAAIGAATGTALARLAAATGTA
                     PAAAPPVRAEAMAETTDRIIALGTSTGGTQALEVVLRGLPRTVPGIVVVQHMPEKFTA
                     MFAQRLDQVCALEVLEARDGQRVIPGRVLIAPGGRHMTLRRSGAQYLVEVRDGPPVNR
                     HRPSVDVLFRSVARCAGRNALGVIMTGMGDDGARGLREMFDAGAQTIAQDEASSVVFG
                     MPKEAIRLGAASRILALPSIGPALEQYARGA"
     gene            complement(6302..6886)
                     /locus_tag="P5537_08335"
     CDS             complement(6302..6886)
                     /locus_tag="P5537_08335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004327600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheD"
                     /protein_id="HRV78088.1"
                     /translation="MRPAARNTIEIFLQPGEFWFGDRDTRIRTLLGSCVSITMWHPRL
                     RIGGMCHFMLPERGARAHADGLDGRYAGDAIELFLRELRAAHTRPQDYQVKLFGGGRM
                     FRSRHAADGPAALDVGTRNVEAARTLLRTHGFRVRAAHVEGEGHRNLIFDIGSGEVWL
                     RHVAPAAASAAVVHGEGGAGADREVPSEAASEAA"
     gene            complement(6889..7698)
                     /locus_tag="P5537_08340"
     CDS             complement(6889..7698)
                     /locus_tag="P5537_08340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004385581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008983 - protein-glutamate
                     O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HRV78089.1"
                     /translation="MSEISITQAEFEQFRALMHQTAGVDLPPQKISLVSGRLARRLRA
                     LGLASFGEYHRLVSSAGARDEFERMVDLLTTHETYFFREPKHFDFLADSVLPALGRTR
                     TPRFWSAASSSGEEAYSLAMVLADRLGGEAPWEVFGSDISREVVEKARGGVYTMNRID
                     GIPPDYLRRYCLRGVGSRDGTLQVDEALRRRVRFAQVNLNGNLAGVGEFDVVFLRNVL
                     IYFDLPTKRRIVERIVRQMRPGGWLFIGHSESLNGLDLGLRQERPTIYRRM"
     gene            complement(7722..8270)
                     /locus_tag="P5537_08345"
     CDS             complement(7722..8270)
                     /locus_tag="P5537_08345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004327597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HRV78090.1"
                     /translation="MTQSSLQTVAPAPVAAAGLRAGAAAGGQYLVFTLGGEVFAIDIL
                     QIREIIEFGELTEVPMTPPTVRGVINLRGAVVPVIDLAARFGRERLRSGRRSCIVIVE
                     VNGDAGTQTLGVMVDGVSEVIDIAAADIEPAPSFGARIRTDFIAGMARREGRFVILLE
                     VGRVFSIDELAGIGALAGAAEH"
     gene            complement(8283..9947)
                     /locus_tag="P5537_08350"
     CDS             complement(8283..9947)
                     /locus_tag="P5537_08350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HRV78091.1"
                     /translation="MFGNMKVGVKLGLGFGLVLVLLGTLLAVGVLRLTDIKRDVDVVV
                     NELWPKNQLLQDGLVGVNEIAMGGRELVIAENGEQIQRAKDRMLGGRERIGKAWDALG
                     PMLVQPRGKELFAEVLDSRQRFIPAQNRLVELVEQGRSDEARAYLRGDYDAIAVQYRQ
                     RVNALTAYQGELLTGTGSETAETVATATLTMSVLGGIALLAGVLVAMLITRGLLRQLG
                     GEPDYAAEIARKVAAGDLTVDVQLRAGDNISLLAGMQRMVGSLSQTLGEVRGAADALS
                     AASEQVSATSQSLAQGSSEQAASLEETSASIEQMSASIGQNTENARVTDGMASKSAAD
                     ADEGGEAVRATVEAMRSIADKIGIVDDIAYQTNLLALNAAIEAARAGEHGKGFAVVAA
                     EVRKLAERSQVAAQEIGELAGSSVKTAERAGALLEEIVPSIRKTAELVQEITASSEEQ
                     SAGAGQINIAMSQISQTTQQNASASEELSATAEEMNSQAEQLQRLVAQFRLDLQAQQA
                     GGDGGAPRAARAHAAPARATREPRRIGLGNPQPAFAAAADPEYVRF"
     gene            complement(9983..>11131)
                     /locus_tag="P5537_08355"
     CDS             complement(9983..>11131)
                     /locus_tag="P5537_08355"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HRV78092.1"
                     /translation="ALIDQVGELVIAGAATQLQAQQAGSRALQETAANLLRLVEDVRD
                     AALRLRMTPIGEVFNRFPRVVRDLARELGKDIELVIRGAEAELDKSMVEKISDPLMHL
                     VRNALDHGIESPARRAEAGKPARGRLELRAFHESGSIVIEVADDGGGLDAQRILAKAV
                     ERGLVAPEAVLSEAEIHRLILAPGFSTAAELTSLSGRGVGMDVVKSSVDALRGSLDIL
                     SAPGQGTTMRLCLPLTLAIIDGFQVGVAGSTFILPLDAVVECIELPASAGADGYLDLR
                     GQVLPFLRLRALFGLEGVPPARQNVVVVRFGGRQAGIAVDRLLGECQAVIKPLGPLFE
                     RVAGIAGSTILGSGEVALILDVPQLVQRAIAHEGRDTGGAPRARFLAA"
     assembly_gap    11132..11231
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<11232..12041)
                     /locus_tag="P5537_08360"
     CDS             complement(<11232..12041)
                     /locus_tag="P5537_08360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hpt domain-containing protein"
                     /protein_id="HRV78093.1"
                     /translation="MDLSQALATFLDESRELLAQMEEILLRAETAALPTDELHALFRC
                     AHTIKGSAGLFGLDAVVHFTHAVESVLDRMRNGELELSDALINLLLESQDHIAGLVAA
                     VAAEAPLPEFEGAPLRARLEAFCATPAALPATLEEGAVAVGAAPAAASAIDVGGGVAL
                     GAEHWHLSLRFAPEVLKNGMDPLAFIHYLRTLGDLVHVETIADALPELATGDPECCYL
                     GFEIALRSAATRAEIESVFEFVQDSARIVLVPPAAHVEEYLALIEALDEDPR"
     gene            complement(12041..12376)
                     /locus_tag="P5537_08365"
     CDS             complement(12041..12376)
                     /locus_tag="P5537_08365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HRV78094.1"
                     /translation="MDIPALDTPADGLARLAPEGELGIYTVAALRETWLQALSTHEAL
                     EVDLGRIDEIDTAGLQLMLMAKRSAGRSVRFVNHSAAVLRLLDLARLGSALGDPLLED
                     AAPATQETR"
     gene            complement(12388..12753)
                     /locus_tag="P5537_08370"
     CDS             complement(12388..12753)
                     /locus_tag="P5537_08370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV78095.1"
                     /translation="MSKTVLIVDDSASLRQVVSLSLKGAGYQVIEACDGRDALGKLGG
                     QKVHLIISDVNMPNMDGIAFVREVKKNPSYKFTPVIMLTTEAAEEKKRLGQEAGARAW
                     VVKPFQPQQMLAAVSKLVM"
     gene            complement(12770..13975)
                     /locus_tag="P5537_08375"
     CDS             complement(12770..13975)
                     /locus_tag="P5537_08375"
                     /inference="COORDINATES: protein motif:HMM:NF012245.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HRV78096.1"
                     /translation="MSQAPQTPAPTDSQLLPLAVHAAPGLAGALLLGLLVPGVAGVAA
                     AVCVGVAGFVLPWSMLRRQRAGQAAAVARLGEAERARLAEREAYLASLQQVAQAALER
                     WHDHVGISRSHTETAVGTLADEFANILEGLQHALLRSRQATADSGEDSVVGVIGYARG
                     ELDRVLAGLNAALAEKQSLSQAVARLAQVTEELMRMASEVGEIAKQTNLLALNAAIEA
                     ARAGEVGRGFAVVADEVRKLSDLSGATGERIRAKVESAHAAMAEALAAAEHMARGDAV
                     LVRDSEAAIGSVVARFDRVGSAMAQAARALEEDSAAVQSRIEGVLVQLQFQDRVSQIL
                     EAVRTDMARLTAQVAEDEARLAGGRVPAPIDVAAWIAALERTYTTLEQHARRADANPA
                     PAGGDITFF"
     gene            14258..15763
                     /locus_tag="P5537_08380"
     CDS             14258..15763
                     /locus_tag="P5537_08380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004385755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HRV78097.1"
                     /translation="MLIRRQQWAIAIASLITIVVVSGLWIANNLALRAELERARMASQ
                     IGPVGAAQMRARIFEFLAQPSPAARERWYESHRALGTLLAPALMDGTPGEPIIAGLRA
                     RHAELPALFEALAADRLREVAGSAPTPELLDAQRLASVHFMDVTQQVAGETLRLLDLS
                     QARLEGLHADQERLIGGLILALALVIGLELFLVHRRILKPLQELHEGARAIETGHYEH
                     RLGMDGKDEIAELGAQFDHMADALGETLQALHQQRSQLEVANRELESFSYSVSHDLRA
                     PLRGIGGWAQALEEDHGGTLPAEAQEYLARIRGECARMNLLIEDLLQLARVTRGDPVF
                     EWLELDLLAREVAERVRESWPGRDIEFAIAPGLRVWGDRSLLGIALANLFDNACKFTA
                     RVPRAHIELGLRELVDAPGGRSLQQYFVRDNGAGFDMKHAARLFVPFQRMHSQREFPG
                     TGIGLAIVQRIIQRHGGTLEAEASPGEGACFRFTLPLLPGPPAPPPNGTPT"
     gene            15774..17309
                     /locus_tag="P5537_08385"
     CDS             15774..17309
                     /locus_tag="P5537_08385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HRV78098.1"
                     /translation="MNPPPNAAAALPPDSRSAPAPRELAVLMVEDSESDALLVLRALR
                     RAGFALRHRRVEEAAEMRAALADETWNVVLSDFNLPGFDARSALAELHASGLDLPFIV
                     VSGTIGDETAIELMRRGAHDYLMKDNLARLAPAIERELGEACVRAERRRALAALHDSE
                     AVLREAQRIGGVGQWRRDLPGGALWCSDTLFGLFGMAPVAGEDAFDALLTRVHPDDLG
                     RLLQAHRELAAGSERVELEYRIVHADGSLRYVLECAARSRGAETATPRLIGTVHDVTA
                     QRAAAEALRTANARLRQMSLRVLDAQEAERRAVAYELHDQIGQALTAVKLDLQAMTPH
                     LDAGPAVARLAAAIHTTEEALAQVRGLSLNLRPPQLDYMGLEASLRWHAERECARAGL
                     VLDFSGGLGEFKAEERCAIVCFRLMQEALNNAVRHAGARRVRIALAVADGRLDMEIAD
                     DGRGFDLARARRRMLEGASVGLLGMEERAALIGGEVRIDAAPGAGTRIRVSLPCTANT
                     APA"
     gene            17319..17999
                     /locus_tag="P5537_08390"
     CDS             17319..17999
                     /locus_tag="P5537_08390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HRV78099.1"
                     /translation="MEGMRVLLVDDHSLVRAGIRALLGSIAGVAGIEEASSGRQAVEL
                     AATMQPDLVLMDIAMDDMDGLAATRAIAAAHPHIKVVILSMHDTGDFFEQALRCGARG
                     YLLKDAAVAELEMAIAAVMRGDVYLSPAVSRHLVGNMLARAPEEERAASVLTPRQTEI
                     LELIGSGLGTKEIARRLDLSVKTVEAHRAQIMERLGVRDIANLLLEAARRGLITLGKR
                     STPLDAPR"
     gene            18099..20237
                     /locus_tag="P5537_08395"
     CDS             18099..20237
                     /locus_tag="P5537_08395"
                     /inference="COORDINATES: protein motif:HMM:NF012772.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HRV78100.1"
                     /translation="MGETVNLLIVEDNESDAALVVRQLERAGYTVATARRVDRAAEFG
                     AALGACAWSAVLCDYALPGFSPEEALAQVQDSGLDLPFLVVSASLGDEDAGRLMALGA
                     HDYVHKHDLARLAPALARGLAEARERRARRHAEDGLRAREAHLRIWSEVVEGLSEGIV
                     VTNLAGDILDCNPAFERITGYARAEVLGLNPRILKSGRHDAAFYAGMWDALVTRGSWV
                     GEVWNRRKSGEVYPERLALRAVHGADGLPTHYVGMFSDLSREKQDQARLDYLTQHDPL
                     TGFANRQLFMERLEQAIERAAAGEGKAAVLLLDLDRFRRVNESLGQDAGDRLLQAMAE
                     RIAGCLRRRSSLARLGSDEFLMLITEFADADALAALARRILDEIARPLTINGQVLHMS
                     ASLGISVHPQDGADAEHLLHAAEAARAQIRHGLGNRLHFFTPGMDTRARRWIAVESEL
                     RHALARGELQLYYQPMVCVRDGRVRTVEALLRWNSPALGWVSPAEFIPVAEESELIVA
                     IGDWVLETACRQVRHWQDTGLPPIRVAVNVSAHQLASGRLPERVREVLEGTGIDPGQL
                     EIELTESAMMTDSEHSARQVEAISRMGVSVSLDDFGTGYSSLAYLSRFALTKLKIDRS
                     FVDGLTSDPKSSIIVDATLGLARGLGLRVVAEGVETEAQRALLAAAGCDALQGYLFSP
                     PVAPAALGALIDRFAPAERYAKPRVFAVSA"
     gene            complement(20256..21155)
                     /locus_tag="P5537_08400"
     CDS             complement(20256..21155)
                     /locus_tag="P5537_08400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HRV78101.1"
                     /translation="MSASGSPRLALLALALLSLIWGYNWVVMKQVIQYVDPFDFSAIR
                     TVLGAATLFVVLLVLRRPLGLQQVRQVALLGVLQTGAFTALIQWALVAGGAGKTAVLV
                     YTMPFWVVPMAWFVLGERVRGMQWAANAIAACGLVLVLEPWAMGGSAFSNLLAVAGGV
                     TWAVASVQAKRMRRAHDFDLLSLTAWQMLFGALALCALALLHPSRPIDPTPYFWGALV
                     FNAVLATGLAWLLWLFVLQRLSTGVAGLSALGIPMVGALAGWIELGERPTPAEFAGMT
                     LIVGALALVSLWSLRQARSTPPR"
     gene            21325..21531
                     /locus_tag="P5537_08405"
     CDS             21325..21531
                     /locus_tag="P5537_08405"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78102.1"
                     /translation="MQRSGRLRRHDGRLAAHQRKVQHRAEQRTEHPPATPPPAVFAPA
                     AELPDWALRSVDLANPLLALDNGL"
     gene            21905..22420
                     /locus_tag="P5537_08410"
     CDS             21905..22420
                     /locus_tag="P5537_08410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AmiS/UreI family transporter"
                     /protein_id="HRV78103.1"
                     /translation="MLLGLSLFYVGAVLILNGLWMLGRIGDREITVINLFTGGLTLLV
                     CLRLALGADADAASIRGAAFSLLFSLTYLWVAWNRLTGGDGRGLGWFSLFVAITAVPI
                     AADTLRAAASTWDWWLGLSWAAWAVLWLMFFLLLALHKPIARATAWMAIVQGVGTAWL
                     PGYLLLTGTLG"
     gene            22691..24190
                     /locus_tag="P5537_08415"
     CDS             22691..24190
                     /locus_tag="P5537_08415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HRV78104.1"
                     /translation="MSDLALQGGGDRVHPVDEKLPGGRLAALGMQHVLVMYAGAVAVP
                     LIVGRALGLSPEQVALLISADLFCCGLVTLIQSLGFGKYFGIKLPVMMGVTFAAVGPM
                     VAMANVQGGPDGARAIFGAIIGAGILSIFIAPFMSRLLRFFPPVVTGTIIAIIGISLM
                     RVGVGWAMGGPAHLAQSVDVPRLVQMVDVAKAKAAEAGVELAKLPGPIPMVNNAGYGA
                     LDTMAVAAFVLVVILLLVRYGRGFVANIAVLLGIVVGCVVAVVMGKMHFDKVAKADWF
                     DLVTPFAFGMPTFDPVMVLTMTLVMVVVMIESVGMFLALGEITDKRISRTELAAGLRT
                     DGLGTLIGGLFNTFPYTSFSQNVGLVGVTGVKSRWVCVAAGVIMIVLGMLPKMAALVE
                     SVPTFVLGGAGLVMFGMVAATGIRILSNVDFRGNRNNLYIVALSIGFGLVPLVAPRWM
                     QHMAHSLHPLLESGILLTAISAVVLNLYFNGGREDKAGAIEAAKAAEAH"
     gene            complement(24320..>25527)
                     /locus_tag="P5537_08420"
     CDS             complement(24320..>25527)
                     /locus_tag="P5537_08420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HRV78105.1"
                     /translation="LAGISVVMGFDVARSLVPMTISEAVFSYELAVVPMFILMGNILA
                     RSGISDDLFRAANAFLGPVRGGLALSTMVTCAGFSAVCGSSLATAATMSKVAYPSMKR
                     YGYSDQLASATIAAGGTLGILIPPSIILMIYGILTQTNIGDLFVAAVIPGILGLVMYL
                     GVVYAIACISPQDAPRGERTTTAEKIRSLRGVWPFTLLFVVIIGGLYGRLFTATEAAG
                     LGAGLALILSIAQRRMSWASFRQIFVETATTSVMLYSVLFGALLFAKLISFSGLGEGM
                     LELVQDAGLGPYQTLAAILILFLLLGCVMESLAIILICVPLFLPILMSHGFDLVWFGI
                     IVVVVTEIALITPPIGMNVFVLKAALPHVRLGAIFRGLFPFVGIDLLRLLLLVAFPSI
                     TLGLVAMMK"
BASE COUNT         3681 a         8954 c         9070 g         3522 t
ORIGIN      
        1 cgcggctgcg agctgttcca gggctatctg ttcggcaggc cggtcccgat cgaggcgtgg
       61 aaggcggact gagcatggcg tacttccatc cgatccacgc ccactctgcg cggcgcagcc
      121 tcggcctgct cgccatcggc ctggcgggac tgatcgcgct gtggtggatt ccgaccccgc
      181 cggggatggc cgggctggcc cactacctcc cgctgcacat ggcgctcgag acgctcgcga
      241 tcgtcgccgc cgtgctggtt ttcgcggtgg cctggctcac cccggagcgc agcacggcgg
      301 tcggcatgcg catcctcgcg tgctgcttcc tcggcgtcgc ggtgctggac ttcagccaca
      361 tgctctcgta ccaggggatg ccggatttcg tcaccccgag cagcccggag aaggcgatcg
      421 acttctggtt cgccgcccgc ctgctcgcgg cgaccgggat gctgctggcg gcgttgctgc
      481 cctggcgggg atgccgcggc gtcacgcccg gcctcgtgct gctcgcggtg ggcgcctacg
      541 tggggctggc acacgcgctc ttcctgctgc ggcccgaatg ggcgccacgg accttcatcg
      601 ccggcgaggg gctgaccgcc ttcaaggtcg gcgtcgagat cgccctgacg ctggcattcg
      661 ccgcatccgc cgccgtgctc gcctggcgca tgcgcaaacc ctgcgccttc gacgcgcccg
      721 ccctgctcgg tgcggcgggc tggatggccc tgagcgagct gttcttcacg atgtacgcgg
      781 acgtcaccga cgtctacaac ctcgccggcc acctgtacaa gatcggcgcg cactacctgc
      841 tcttccgcgc gctggtggtc gacggcatcc gcgcacccta cgcggcgctc gagcgctcgc
      901 gcaccgagct cgcggagaac tcctcacggc tgaccgacga acaccgccgc ctcgaatcca
      961 tcctggccgg cacccgcgcc ggcacctggg agtggaacgt gcagaccggc gagaccatct
     1021 tcaatgcgcg ctgggcggag atgctgggct atcgcctcga agagctcgag ccgatctcga
     1081 tcgacacctg gcggcgcttc gcccatccgg acgatctcgc cgactcggac gccgcgatac
     1141 accgtcatct tcgtggcgaa acaccgtatt acgagcacga gtcccgcatg cgccatcgcg
     1201 cagggcactg gatccgcgtg caggaccgcg gcgcgctgcg cacccttacc gacaagggcg
     1261 agcccgaatg gatgttcggc acccatatcg acgtcagcga ccggcatcgc gcggagcagg
     1321 agcgcggcga ggcgctgaac cgcctgcgcc agctctcgga cagcgtgccc ggcgtgctgt
     1381 tcgagtgccg cgtggaagcc gacggcagga tggttttccc ctacgtcggc cggcaggtcg
     1441 acgagttgat cggctgccga gccgaggacg tggtggacga cgccacggcg ttctacgccc
     1501 gcctgcatcc cgacgaccgt gctcaggtca tcgaggaggt ccgccgcgcg aaggacgccc
     1561 tgcaggactg gtccgcgtcc ttccgcgtcc tccaccccgt gcacggcgag cgccggatcc
     1621 gtggcgaggc gcgctgccag gcgcagcccg acggcgccgg cgagtggttc ggctaccttc
     1681 aggacgagac cgaggcccac cggaaccagg agtggctgcg cctctccgcc cgcgtgttcg
     1741 acgccagcca ggagggcatc ctggtcaccg acgccgaggt ccgcatcgtc gacgcgaatc
     1801 cggcgatgga ggcactgacc gggtacgcca gggatgcgct gctcggccgc aacccgagcg
     1861 tgctccgctc gggccggcac gacgccgcct tcttcgccgc gatgtacacg aagctgcagc
     1921 atgacgggcg ctggcagggc gagatgtgga accggcaccg ctcgggcgag atctacgtgg
     1981 tcaaggtttc gatctccacc gtacgtgacg agtccgggcg gatcgagcat tacgtggccg
     2041 tgttcaccga catcagcaag ctgatggcgc agcgcgacca cttcagctcg ctcgccaact
     2101 tcgacgccct caccggcctg cccaaccgcc gcctgctcga ggaccgcctg caccaggcgg
     2161 tgggcaacgc gcgccgcggc aagcatctgg tggtgtgcat gctcgacctc gacggcttca
     2221 aggcggtcaa cgacagcgcc ggccacgccg agggcgaccg cctgctgatc gagctcgcac
     2281 agcgcatgca gcacatcctg cgcgcgggcg agacgctggc ccgcctcggc ggcgacgagt
     2341 tcgtcctgct gctggtggac ggcgacttcc gtccggcgct cgagcgtgtg ctcgaggtgg
     2401 cgcgcgcgcc ggtggcgctg tgcggcggcg gcttcgcccg cgtcaccgcg agcatcggcg
     2461 cgagcgcgta ccggcacggc gtcgaggacg gcgcacaatt gctgcgcgag gccgatcacg
     2521 ccctctaccg cgccaagcgc gccggacgca accgctgggt gatgttcgcg ccggaagatg
     2581 cggccgggtc ggagacgccg ccggcctagc ccagcgtcgt ggtcgcgagc ttggcgccga
     2641 agccgatgaa gaccccgccc acccccgccg tggcccccgc ggcgacgcgg cggtgacggc
     2701 ggaactgcgc ggccaggcgc gcaccggcga agatcagcgt ggacaggtag agcacgctgc
     2761 agatctgcac gatcacgccc aggatcacga aggacagcgc ggggtgctca taggccggat
     2821 cgacgaactg gatgaagaag gacacgaaga acaggatcgc cttcgggttc atcaggctga
     2881 tcagcagcgc ggtgcggaag gggtgcggcg tgctgcgcac cggcgggtag tcgggcttgc
     2941 cgtcgcctac ctgcgccgcc gtctcgtcgc cgcgccgcca ggtcgccagt gccccgcgca
     3001 gcagagccag ccccacccag gccaggtagg ccgcgccggc gtacttgatc accatgaaca
     3061 gctcgggcgt ggcgcgcagc accgaggcca tgccggtcac cgcgagcagc atcaggatgg
     3121 tgtcgccgac gaagatcccc gccgcgccct ggtagccggc gcgcacgccc cagcgcgagg
     3181 ccgcggccat cacgtagagc gagttgggcc cgggcagcag cacgatgaag acggtgccga
     3241 ggacgaaggt gaagaggtcg gtgatgccgt agaacatgat ggcgggcgcg caggctggaa
     3301 gtgggggatg gggcaggagg gcaggagggc aggagggcag gcagctactt tgccacgacc
     3361 gcccgctcgc ggccaggcgc cgccgccttc gcgcctgccg gcgctcctac agaaaccacc
     3421 gcattttcgg cctgnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnngcggca
     3541 gctgcgaaca aggccgtacc gaaccggccg cgcgtgccac cctccgccgc cttcgcgcct
     3601 gccggcgctc ctacagaaac caccgcattt tcggcctgca ggagctgcgg cagctgcgaa
     3661 caaggccgta ccgaaccggc cgcgcgtgcc accctccgcc gtcttcgcgc ctgccggcgc
     3721 tcctacacgc ctccccgagc tcttgcgcgc ggacatcgca agattcgcgc ctgccggcgc
     3781 tcctgcatcc ccccgaggcc ttgcgcgcgg gcagggacgg gttcatgtag gagcgccagc
     3841 aggcgcgaag gcggccgcgc tcattggcgc tgcgcgacga actccagcgg cgcatcgacc
     3901 gaatggctgc ggcggatctg caggcgcacg cgcagggtct cgccttcgcg ccagacttca
     3961 tagagctggc ccatctcgcg tggcggctcg tcgccggata cggtctcgct gcgggtgagg
     4021 aagcgcagcc ggccgtcgtc ccactccact gcctcgagca cgcgcggcac gccgaggaag
     4081 ctggcgctgc cgccgatgcg gccgtccgcc agcgtgaaca cgtagtgctc gcgcagcgtc
     4141 aggttccatg gataggcgac ctcggcgctc cattcgccga cgagcgcctg cggcccccgg
     4201 tcggcacccc gcaaccacca ccacccgcca ccgagcacga ggagcagcgc cgcgatcgcg
     4261 gccgcaagcg cccggcgtcc gcgcaccggc ttcgagggcg cggccggttc cacccattgc
     4321 gccagcgcgg cctccaggcg ggcgagcgcc gcgcgccagc cggcgtcgcc gagcgcaagc
     4381 gcgttgcggt tggccagccc gcgcagtgtg ggcggcagcg cctcggccgc cggcatcgtc
     4441 gccccgccga ccagcaccgg gatcaggggc ttgccggagg cgagcgcgag ctcaacctcg
     4501 cggcgcacgt agtcgccggg atcgtcgagc cggcgcccac gctcgtcgcg cgcgtcgagc
     4561 cagcgcggcc cgatcaccac cagcaccgcc tgcacctgct gcagggcctg ctcgatgacc
     4621 acgccgaagt ccgcccctgc ggcaatgtcg tcgacgtcgc ggaacacgct gtcggcgccg
     4681 aagcgacgct cgagcgcatc ggtgagccgg ccggcgaagc cggcgctgtc gtcacggcgg
     4741 taggagacga agaccttgga catggtgtcg catcgggggg atttcctgca ttcaagcacg
     4801 ccccccgccc ccacgccacc cgcgcggccc ggttcgcgcc tgccggcgct cctacatccc
     4861 tccagaaggc gcgccggttc attgnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4981 nnnncatccc tcccggaggc ggggcggttt ccggaaggcg cgaaggcggt ggctcaggcg
     5041 ccgcgggcgt attgctcgag ggcggggccg atggacggga gggcgaggat gcggctggcg
     5101 gcgccgaggc ggatggcttc cttgggcatg ccgaagacga ccgagctggc ctcgtcctgg
     5161 gcgatggtct gggcgccggc gtcgaacatc tcgcgcaggc cgcgggcgcc gtcgtcgccc
     5221 atgccggtca tgatcacgcc gagagcgttg cgcccggcgc agcgggctac cgagcggaag
     5281 agcacgtcga ccgaggggcg gtggcggttg accggcgggc cgtcgcgcac ctcgacgagg
     5341 tattgcgcgc cgctgcgccg cagcgtcatg tggcggccgc caggggcgat gagcacgcgc
     5401 ccggggatca cacgctgacc gtcgcgggcc tcgagcacct cgagcgcgca cacctgatcg
     5461 aggcgctggg cgaacatcgc ggtgaatttc tccggcatgt gctggaccac gacgatgccg
     5521 ggcaccgtgc gcggcaggcc gcgcagcacg acctcgaggg cctgggtgcc gccggtggag
     5581 gtgccgagcg cgatgatgcg atcggtggtc tcggccatcg cttcggcgcg caccggcggc
     5641 gcggccgcgg gcgccgtccc ggtcgccgcg gccaggcgcg caagcgcggt gccggtggcg
     5701 gcaccgatgg cggcgccgga acccgaggcc gtccctgcgc tcgcccgcgg cccgcccggg
     5761 ccggcgcccg ccagcccgcg cgcaggcacc acgccgaagc ccgaaccggc agcggcagcg
     5821 gattcgactt ccgcacccgc ccccgctcgg ccgcctaccc cgcccaaccc gacccctgca
     5881 ccggcccgca gcgcgcgcag gttcgcgcgc gccgcggcgc gcacggcggc gacgagctcc
     5941 tgggcggagt cgttgaggaa gcccttcagc cccagcgtgg gcttggcgat gatggagacg
     6001 gcgccggcgg cgagcgcttg catggtggtc tcggcgccgc gcgaggtgag cgtggaacat
     6061 acgatcaccg gggtcgggcg ctcggccatg agctggcgca ggaagctgat gccgtccatg
     6121 cgcggcatct cgacgtcgag cgtgatgacg tccggccagt cgcggcgcat cctggccatg
     6181 gcgaagatcg ggtcggaggc ggtgccgacg acctcgatgc cgggcgcagc ggagaggatc
     6241 tcgctcatca cctggcgcac cacggcggaa tcgtcgacga cgaggacacg gatcggagcg
     6301 gtcatgcggc ctcgctcgcg gcttcagagg gtacttcgcg gtcggctccg gcaccgcctt
     6361 cgccgtgcac gaccgcagcg ctcgccgccg ccggggcgac gtgacgcagc cagacctcgc
     6421 cgctgccgat gtcgaagatc aggttgcggt ggccctcgcc ctcgacgtgc gcggcgcgca
     6481 cgcgaaagcc gtgcgtgcgc agcagcgtgc gcgcggcctc gacgttgcgc gtgccgacgt
     6541 cgagcgcggc ggggccgtcc gcggcgtggc gggagcggaa catgcgcccg ccgccgaaga
     6601 gcttgacctg gtaatcctgc ggccgggtgt gcgcggcgcg cagctcgcgc aggaaaagtt
     6661 cgatcgcgtc gccggcgtag cgcccgtcca ggccgtcggc gtgcgcacgc gcgccgcgct
     6721 cgggcagcat gaagtggcac atgccgccga tgcgcaggcg cgggtgccac atcgtgatcg
     6781 acacgcagga gccgagcagg gtgcggatgc gcgtgtcgcg gtcaccgaac cagaactcgc
     6841 cgggctgcag gaagatctcg atggtgttgc gcgcggccgg ccgcatgctc acatccgccg
     6901 gtagatcgtc ggccgctcct ggcgcaggcc gaggtcgagg ccgttgaggc tctcggagtg
     6961 gccgatgaac agccagccgc ccggccgcat ctggcgcacg atgcgctcga cgatacggcg
     7021 cttggtgggg agatcgaagt agatgagcac gttgcgcagg aagacgacgt cgaactcgcc
     7081 gacgccggcg aggttgccgt tgagattgac ctgggcgaag cgtacccgcc ggcgcagcgc
     7141 ctcgtcgacc tgcagcgtac cgtcgcggct gccgacaccg cgcaggcagt agcgccgcag
     7201 gtagtcgggc gggatgccgt cgatgcggtt catcgtgtag acgccgccgc gcgccttctc
     7261 caccacctcg cggctgatgt ccgagccgaa cacttcccag ggcgcctcgc cgccgaggcg
     7321 gtcggcgagc accatcgcca ggctgtaggc ctcctcgccg gaggagctcg ccgcactcca
     7381 gaagcgcggc gtgcgcgtgc gcccgagcgc gggcagcacg ctgtcggcga gaaagtcgaa
     7441 gtgcttgggc tcgcggaaga agtaggtctc gtgggtggtg agcaggtcga ccatgcgctc
     7501 gaactcgtcg cgcgccccgg cactcgacac caggcggtga tactcgccga agctggcgag
     7561 cccgagcgcg cgcagccgcc gcgccaggcg gccgctgacc aggctgatct tctgcggcgg
     7621 caggtcgacg ccggcggtct ggtgcatgag cgcacggaac tgctcgaact cggcctgggt
     7681 gatgctgatc tcggacatgc ggaccctccg gggagaccgg ctcagtgctc ggcggcgccg
     7741 gcgagcgcgc cgatgccggc gagctcgtcg atcgagaaca cccgcccgac ctcgagcagg
     7801 atcacgaagc gcccttcgcg gcgcgccatg ccggcgatga agtcggtgcg gatgcgggcg
     7861 ccgaaggacg gcgccggctc gatgtcggcg gcggcgatgt cgatgacctc gctgaccccg
     7921 tcgaccatca cgccgagcgt ctgcgtgccg gcgtcgccgt tcacctcgac gatgacgatg
     7981 cagctgcgcc gcccgctgcg caggcgctcg cggccgaagc gcgcggcgag gtcgatcacc
     8041 ggcaccaccg cgccgcgcag gttgatcacc ccgcgcacgg tgggcggcgt catcggcacc
     8101 tcggtgagct cgccgaattc gatgatctca cggatctgca ggatgtcgat cgcgaacacc
     8161 tcgccgccga gcgtaaacac caggtactgg ccgcccgcgg ccgcgccggc gcgcagcccg
     8221 gccgcggcga ccggcgccgg ggcgaccgtc tgaagactgg attgcgtcat ggccggctcc
     8281 gctcagaagc gcacgtattc cgggtccgcg gcggcggcga aggccggctg cgggttgccc
     8341 aggccgatgc ggcgcggctc gcgcgtggcg cgcgcggggg ccgcgtgggc gcgggcggcg
     8401 cgcggggcac cgccgtcacc gccggcctgc tgcgcctgca ggtcgaggcg gaactgcgcc
     8461 accaggcgct gcagctgctc ggcctggctg ttcatctcct cggcggtcgc cgacagctcc
     8521 tccgaggccg aggcgttctg ctgcgtggtc tggctgatct ggctcatggc gatgttgatc
     8581 tgccccgcgc cggccgactg ttcctcggac gaggcggtga tctcctgcac gagctcggcg
     8641 gtcttgcgga tcgagggcac gatctcctcg agcagggcac cggcgcgctc ggccgtcttg
     8701 acgctggagc cggcgagctc gccgatctcc tgcgccgcga cctggctgcg ctcggccagc
     8761 ttgcgcacct cggccgccac caccgcgaag cccttgccgt gctcgccggc gcgcgccgcc
     8821 tcgatcgcgg cgttgagcgc gagcaggttg gtctggtagg cgatgtcatc gacgatgccg
     8881 atcttgtcgg cgatcgaacg catcgcctcg accgtcgcgc gcaccgcctc gccgccctcg
     8941 tcggcgtcgg cggcggactt gctcgccatg ccgtcggtga cgcgggcgtt ctcggtgttc
     9001 tggccgatcg aggcggacat ctgctcgatc gaggccgagg tctcctcgag gctggcggcc
     9061 tgctcggaag atccctgcgc cagcgactgc gaggtcgcgc tcacctgctc ggaggctgcg
     9121 gacagggcgt cggccgcgcc gcgcacctcg cccagggtct gcgacaggct gcccaccatg
     9181 cgctgcatcc ccgcgagcag gctgatgttg tccccggcgc gcagctgcac gtccaccgtg
     9241 agatcgccgg cggcgacctt gcgtgcgatc tccgccgcat agtcgggctc gccgccgagc
     9301 tggcgcagca gcccgcgggt gatcagcatg gccaccagga cacccgccag cagcgcgatg
     9361 ccgcccagca cggacatggt cagcgtggcc gtggcgacgg tctcggcggt ctcgctgccg
     9421 gtgccggtga gcagctcgcc ctggtaggcg gtcagcgcgt tgacgcgctg gcggtactgc
     9481 accgcgatgg catcgtagtc gccacgcagg taggcgcgcg cctcgtcgct gcggccctgc
     9541 tcgacgagct cgacgaggcg gttctgcgcc gggatgaagc gctggcggct gtcgagcacc
     9601 tcggcgaaga gctccttgcc gcgcggctgc accagcatcg gcccgagcgc gtcccaagcc
     9661 ttgccgatgc gctcgcgccc gccgagcatg cgatccttgg cgcgctggat ctgctcgccg
     9721 ttctcggcga tcaccagctc gcgcccgccc atggcgatct cgttcacccc gaccaggccg
     9781 tcctgcagca gctggttctt gggccagagc tcgttcacca ccacgtcgac atcgcgcttg
     9841 atgtcggtca gccgcaggac gcccaccgca agcagcgtcc ccagcaggac cagcacgaga
     9901 ccgaagccca gccccagctt cacacccacc ttcatgtttc cgaacatttt cattcccctg
     9961 tttccgtttt cttcaacagc attcatgcag cgaggaagcg cgcccgcggc gcgcccccgg
    10021 tgtcgcggcc ctcgtgcgcg atcgcacgct ggaccagttg tggcacatcc aggatcagcg
    10081 ccacctcgcc gctacccagg atggtggagc cggcgatgcc ggcgacgcgc tcgaagagcg
    10141 gcccgagcgg cttgatcacc gcctggcatt cgccgagcag gcggtccacc gcgatccccg
    10201 cctggcgccc gccgaagcgc accaccacga cgttctgccg cgccggcggc acgccctcga
    10261 gaccgaacag tgcgcgcagg cgcaggaagg gcaggacctg gccgcgcagg tcgaggtagc
    10321 cgtcggcgcc ggcactcgcc ggcagctcga tgcactcgac caccgcgtcg agcggcagga
    10381 tgaaggtgga gccggcgacg ccgacctgga agccgtcgat gatcgccagc gtgagcggca
    10441 ggcacagccg catcgtggtg ccctgccccg gcgcgctgag gatgtcgagg ctgccgcgca
    10501 gcgcatccac gctgctcttg acgacgtcca tgccgacgcc gcggccggac aggctggtaa
    10561 gctcggccgc ggtggagaag cccggcgcga ggatcaggcg gtggatctcg gcctcggaga
    10621 gcacggcctc gggcgccacc aggccgcgct cgacggcctt ggcgaggatg cgctgcgcat
    10681 ccagcccgcc gccgtcgtcg gcgacctcga tgacgatgct gccggactcg tggaacgcgc
    10741 gcagctcgag ccggccacgc gccggcttgc ccgcctcggc gcggcgcgcg ggcgattcga
    10801 tgccgtggtc gagggcgttg cgcacgaggt gcatgagcgg gtcactgatc ttctcgacca
    10861 tggacttgtc gagctcggcc tcggcgccgc ggatcaccag ctcgatgtcc ttgccgagct
    10921 cgcgcgcgag gtcgcgcacc acgcgcggga agcggttgaa gacctcgccg atcggggtca
    10981 tgcgcaggcg cagcgcggcg tcgcgcacgt cctcgaccag gcgcagcagg ttggcggcgg
    11041 tctcctgcag cgcgcggctg ccggcctgct gcgcctgcag ctgggtggcg gcgccggcga
    11101 tcacgagctc gccgacctgg tcgatgaggg cnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11221 nnnnnnnnnn ngcgcgggtc ctcgtcgagc gcctcgatga gggcgaggta ctcctcgacg
    11281 tgcgccgccg gcggcaccag cacgatgcgc gcgctgtcct gcacgaactc gaacaccgat
    11341 tcgatctcgg cgcgcgtggc tgcgctgcgc agcgcgatct cgaagccgag gtagcagcac
    11401 tccggatcgc cggtggcgag ctcggggagg gcgtcggcga tcgtctcgac gtgcaccaga
    11461 tcgccgagcg tgcgcaggta gtggatgaag gcgagcggat ccatgccgtt cttcagcacc
    11521 tcgggcgcga agcgcagcga caggtgccag tgctcggcgc cgagtgccac gccgccgccg
    11581 acgtcgatcg cggacgcagc tgcgggtgcc gcaccgacgg ccaccgcccc ctcctccagc
    11641 gtcgccggca acgcggcagg cgtggcgcag aaggcttcga ggcgggcgcg cagcggtgcg
    11701 ccctcgaatt ccggcagggg cgcctcggcg gcgaccgcgg cgacgaggcc ggcgatgtgg
    11761 tcctgcgact cgagcagcag gttgatgagg gcgtcggaga gttcgagctc gccgttgcgc
    11821 atgcggtcga gcacgctctc gacggcgtgg gtgaagtgca ccaccgcgtc cagcccgaac
    11881 aggccggccg agcccttgat ggtgtgggcg cagcggaaca gcgcgtgcag ctcgtccgtg
    11941 ggcagcgcgg cggtctcggc gcgcaggagg atctcctcca tctgcgcgag cagctcgcgg
    12001 ctctcgtcga ggaaggtggc cagggcctgg gagaggtcca tcagcgtgtc tcctgcgtgg
    12061 cgggcgcggc atcctcgagc agcgggtcgc cgagcgcgct gccgaggcgg gcgaggtcga
    12121 gcaggcgcag caccgcggcg gagtggttga cgaagcgcac gctgcgcccg gcgctgcgct
    12181 tggccatcag catgagctgc aggccggcgg tatcgatctc gtcgatgcgg ccgaggtcca
    12241 cctcgagcgc ttcgtgggtg gagagcgcct gcagccaggt ctcgcgcagc gcggccacgg
    12301 tgtagatgcc gagctcgcct tcgggggcga ggcgggcgag gccgtcggcg ggggtgtcca
    12361 gggcggggat atccatggtc ggcacgctca catcaccagc ttggacaccg ccgccagcat
    12421 ctgctgcggc tggaagggct tgaccaccca ggcgcgcgcg ccggcctcct ggccgaggcg
    12481 cttcttctct tcggcggcct cggtggtgag catgatcacc ggggtgaact tgtagctcgg
    12541 gttcttcttg acctcgcgca cgaaggcgat gccgtccatg ttgggcatgt tcacgtcgga
    12601 gatgatgagg tgaaccttct ggccaccgag cttgccgagg gcgtcgcggc cgtcgcaggc
    12661 ctcgatgacc tggtagccgg cgcccttgag cgacaggctc accacctggc gcagcgaggc
    12721 ggagtcgtcg acgatcagca cggtcttgga catgggggat tactcctgct caaaagaagg
    12781 tgatgtcgcc accggccgga gcggggttcg cgtcggcgcg gcgtgcgtgt tgttcgaggg
    12841 tggtgtaggt gcgctcgagc gcggcgatcc aggcggcgac gtcgatcggc gccggcaccc
    12901 gcccgccggc gagacgggcc tcgtcctcgg cgacctgggc ggtcaggcgc gccatgtcgg
    12961 tgcgcaccgc ctcgaggatc tggctgacgc gatcctggaa ctggagctgc accagcacgc
    13021 cctcgatgcg ggactgcacc gcggcgctgt cttcctcgag cgcgcgcgcg gcctgcgcca
    13081 tggcgctgcc gacccggtcg aagcgcgcga ccacgctgcc gatggcagcc tcggagtcgc
    13141 gcaccaggac ggcgtcgccg cgagccatgt gctcggccgc ggcgagcgcc tcggccatcg
    13201 cggcgtgggc gctctcgacc ttggcgcgga tgcgctcgcc ggtggcgccg gagaggtcgg
    13261 agagcttgcg cacctcgtcg gcgaccaccg cgaagccgcg ccccacctcg ccggcgcgcg
    13321 cggcctcgat cgccgcgttg agcgcgagca ggttggtctg cttggcgatc tcgccgacct
    13381 cgctcgccat gcgcatcaat tcctcggtga cctgggcgag tcgggcgacc gcctgcgaca
    13441 ggctctgctt ctcggcgagc gcggcgttga gcccggcgag cacgcggtcg agctcgccgc
    13501 gggcgtagcc gatcaccccg accacgctgt cctcgccgct gtcggcggtg gcctggcgcg
    13561 agcgcagcag cgcgtgctgc agcccttcga ggatgttcgc gaactcgtcc gcgagcgtgc
    13621 ccacggcggt ctcggtgtgg ctgcgcgaga tgcccacgtg gtcgtgccag cgctccagcg
    13681 ccgcctgcgc cacctgctgc aggctcgcaa gataggcctc gcgctcggcc aggcgcgcac
    13741 gctcggcctc gccgaggcgc gccacggcgg cggcctggcc cgcgcgctgg cggcgcagca
    13801 tcgaccacgg cagcacgaaa ccggccacgc cgacgcagac cgctgcggcg acgcctgcca
    13861 cgcccggcac gagcaggccg agcagcagcg caccggccag cccgggggcg gcgtgcacgg
    13921 ccagaggcag gagctgcgaa tccgtcgggg cgggagtctg gggagcttgg gacacttggg
    13981 cgttctccat tgttgccgtg ctcgccttgc gacggcgggg cgattcgtct gccttccgga
    14041 cctcgctcac ggaacattcc acgcgaagat ggacccaatc cggggagtgc cgttaacatc
    14101 cgggcccgcc gcgcatttgc cggcgacatg cactttcttt gcatgcatca tcccggtatg
    14161 gggcgtctag ggacaatcgg taaaattccg tgcgtgtccc taggggattg gactagtcgg
    14221 acagcaggag caggctcatc gacacggagg gattcgcgtg ctgatccgca ggcagcaatg
    14281 ggcgatcgcg atcgcctcgc tgatcaccat cgtggtggta agcggactgt ggatcgcgaa
    14341 caacctggcc ttgcgcgccg agctcgagcg cgcccgcatg gcgtcgcaga tcgggccggt
    14401 gggggcggcg cagatgcgtg cgcgcatctt cgagttcctc gcccagccct cgccggcggc
    14461 gcgggagcgc tggtacgaga gccaccgggc gctcggcacg ctgctggcac ccgcactgat
    14521 ggacggcacc cccggtgagc cgatcatcgc gggcctgcgt gcacgccacg cagaactgcc
    14581 ggcgctgttc gaggcgcttg ccgccgatcg cctgcgcgag gtcgcaggca gcgcgcccac
    14641 gcccgagctg ctggatgcgc agcgcctcgc ctccgtccat ttcatggacg tgacgcagca
    14701 ggtggccggc gaaaccctgc gcctgctcga tctgagccag gcgcggctgg aaggcctgca
    14761 cgccgatcag gagcgcctga tcggtggcct catcctcgcc ctggcgctgg tgatcgggct
    14821 cgagctcttc ctggtgcacc gccgcatcct caaacccctg caggagctgc acgagggcgc
    14881 gcgtgcgatc gagacgggcc actacgagca ccgcctcggc atggacggca aggacgagat
    14941 cgcggagctc ggcgcacagt tcgaccacat ggccgacgcg ctcggcgaga ccctgcaggc
    15001 cctgcaccag cagcgcagcc agctcgaagt cgccaaccgc gagctggaga gcttcagcta
    15061 ctcggtgtcg cacgacctgc gcgcaccgct gcgcggcatc ggtggctggg cgcaggcgct
    15121 cgaggaggat catggcggca cgctgcccgc ggaggcgcag gaatacctcg cgcgcatccg
    15181 cggcgagtgc gcgcgcatga acctgctcat cgaggatctg ctacagctgg cgcgcgtcac
    15241 ccgcggcgac ccggtattcg aatggctgga gctcgatctg ctcgcccgcg aggtggccga
    15301 gcgcgtgcgc gagagctggc cggggcgcga catcgagttc gcgatcgccc cggggctgag
    15361 ggtgtggggc gaccgcagcc tgctcgggat cgccctcgcc aacctgttcg acaacgcctg
    15421 caagttcacg gcgcgcgtgc cgcgggcgca catcgagctc ggtctccggg agctcgtcga
    15481 tgcccccggc gggcgcagcc tgcagcagta cttcgtgcgc gacaacggcg cgggcttcga
    15541 catgaagcac gcggcccggt tgttcgtccc cttccagcgc atgcactcgc agcgcgagtt
    15601 tcccggcacc ggcatcgggc tggcgatcgt gcagcgcatc atccagcgcc atggtggcac
    15661 actggaggcc gaggccagtc cgggcgaggg cgcctgcttc cgcttcaccc tgccgctgct
    15721 gcccggcccg ccggcccctc caccgaacgg aacgccaaca tgaggcgaac gcattgaatc
    15781 cgcccccgaa cgccgccgcg gccctccctc cggacagtcg cagcgcaccc gcgccacgcg
    15841 agctcgccgt gctgatggtg gaggactccg agagcgacgc gctgctggtg ctgcgtgcgc
    15901 tgcgccgcgc cggcttcgcg ctgcgccatc gccgcgtcga ggaggctgcc gagatgcgcg
    15961 cggcgctcgc cgacgagacc tggaacgtcg tgctgtcgga cttcaacctg cccggcttcg
    16021 acgcgcgcag cgcgctcgcc gagctgcacg cgagcgggct cgacctgccc ttcatcgtgg
    16081 tgtcgggcac catcggcgac gagaccgcga tcgagctgat gcgccgcggc gcccacgact
    16141 acctgatgaa ggacaacctc gcccgcctcg cccccgcgat cgagcgcgag ctcggcgagg
    16201 cgtgcgtccg cgccgagcgc cggcgcgcgc tcgccgcgct gcacgacagc gaggcggtgc
    16261 tgcgcgaggc gcagcgcatc ggcggggtcg ggcagtggcg cagggacctg ccaggcgggg
    16321 cgctgtggtg ctcggacacc ttgttcgggc tcttcggcat ggccccggtg gcgggagagg
    16381 atgcgttcga cgccctgctc acccgcgtgc acccggacga cctcgggcgc ctgctgcagg
    16441 cacaccgcga gctcgccgcc ggcagcgagc gcgtcgagct ggagtaccgc atcgtccatg
    16501 ccgacggcag cctgcgctac gtgctcgagt gcgccgcccg cagccgcggc gccgagaccg
    16561 cgacgccgcg cctgatcggc acggtgcacg acgtcaccgc gcagcgcgcc gcggccgagg
    16621 ccttgcgcac cgccaacgcg cgcctgcgcc agatgtcgct gcgcgtgctc gacgcccagg
    16681 aggccgagcg ccgcgcggtg gcctacgagt tgcacgacca gatcggccag gcgctcacgg
    16741 cggtcaagct cgacctgcag gcgatgaccc ctcatctgga cgccggcccg gcggtggcgc
    16801 gcctggccgc ggccatccac accaccgagg aggcgctcgc gcaggtgcgc ggcctgtcgc
    16861 tcaacctgcg cccgccgcag ctcgactaca tggggctgga agcctcgctg cgctggcacg
    16921 ccgagcgcga atgcgcgcgc gccgggctgg tgctcgattt ctccggcggt ctcggcgagt
    16981 tcaaggccga ggagcgctgc gcgatcgtgt gcttccggct gatgcaggag gcactgaaca
    17041 acgccgtacg ccatgccggc gcgaggcggg tgcgcatcgc gctggcggtc gcggacggcc
    17101 gcctcgacat ggagatcgcc gacgacggcc gcggcttcga cctcgcgcgc gcgcgccggc
    17161 gcatgctgga gggcgccagc gtgggtctgc tcggcatgga ggagcgcgcg gcgctgatcg
    17221 gcggcgaggt gcgcatcgac gccgctcccg gcgcgggcac ccgcatccgg gtaagcctgc
    17281 cctgtaccgc aaacaccgcc ccggcgtagg attcggtcat ggaaggaatg cgagttctgc
    17341 tggtggacga tcacagcctg gtgcgcgcgg gcatccgcgc gctcctgggc tcgatcgcgg
    17401 gtgtggccgg catcgaggaa gcgagcagcg gccgccaggc ggtcgagctg gcggcgacga
    17461 tgcagcccga cctggtgctg atggacatcg cgatggacga catggacggc ctcgccgcca
    17521 cgcgcgcgat cgccgcggcg catccgcaca tcaaggtggt gatcctgtcg atgcacgaca
    17581 ccggcgactt cttcgagcag gcgctgcgct gcggcgcgcg cggctacctg ctcaaggacg
    17641 ccgcggtggc cgagctcgag atggcgatcg cggcggtgat gcgcggcgac gtctacctga
    17701 gccctgcggt gtcacgccac ctcgtaggca acatgctcgc gcgcgcgccc gaggaagaac
    17761 gcgcggcgag cgtgctgacc ccgcgccaga ccgagatcct cgagctcatc ggcagcggcc
    17821 tcggcaccaa ggagatcgcc cgccggctcg acctcagcgt caagaccgtg gaggcgcacc
    17881 gcgcccagat catggagcgc ctgggcgtgc gcgacatcgc caacctgctg ctggaggccg
    17941 cgcgccgcgg cctcatcacc ctcggcaagc gctccacacc cctagacgcg cctcggtaat
    18001 ccaggggatt gtcgccgcgc cccggcggcc tatcatggcg gcatggaccg aagtgccgga
    18061 gtgcgattcc ggccgcacac cgctgaggaa gggcaagcat gggcgagacc gtcaatctgc
    18121 tgatcgtcga ggacaacgaa tccgatgccg cgctggtggt acgccagctc gagcgcgccg
    18181 gctatacggt ggcgaccgcg cgccgcgtcg atcgcgccgc ggagttcggt gccgccctcg
    18241 gggcctgcgc gtggtcggcg gtgctgtgcg actacgccct gcccggcttc agccccgagg
    18301 aggcgctcgc ccaggtacag gatagcgggc tggacctgcc cttcctggtc gtctcggcct
    18361 cgctcggcga cgaggacgcc ggccgcctga tggcgctcgg cgcgcacgac tacgtgcaca
    18421 agcacgacct cgcgcgcctc gccccggcgc tggcgcgcgg cctggccgag gcacgcgagc
    18481 gccgggcccg ccgccacgcc gaggacggtc tgcgcgcgcg cgaagcgcac ctgcgcatct
    18541 ggagcgaggt ggtcgagggc ctgagcgagg gcatcgtggt caccaacctc gccggcgaca
    18601 tcctcgactg caacccggcc ttcgagcgca tcaccggcta cgcccgtgcg gaagtgctcg
    18661 ggctgaaccc gcgcatcctg aagtccggcc gccatgacgc cgccttctac gccggcatgt
    18721 gggacgcgct ggtcacccgc ggctcgtggg tgggcgaggt atggaatcgg cgcaagagcg
    18781 gcgaggtcta ccccgagcgc ctggccttgc gcgcggtgca cggcgccgac ggcctgccca
    18841 cgcactacgt gggcatgttc agcgacctca gccgcgagaa gcaggaccag gcccggctcg
    18901 actacctgac ccagcacgac ccgctcaccg gcttcgccaa ccgccagctc ttcatggaac
    18961 gcctggagca ggcgatcgag cgcgccgccg ccggcgaggg caaggccgcg gtgctgctgc
    19021 tcgacctcga tcgcttccgg cgggtgaacg agagcctcgg ccaggacgcc ggcgaccgcc
    19081 tgctgcaggc catggccgag cgcatcgccg gctgcctgag gcggcgcagc agcctcgccc
    19141 gcctgggcag cgacgagttc ctcatgctga tcaccgagtt cgccgacgcg gacgcgctgg
    19201 cggcgcttgc gcggcgcatc ctcgacgaga tcgcccgtcc gctgacgatc aacggccagg
    19261 tcctgcacat gagcgcgagc ctgggcatca gcgtccatcc ccaggacggc gccgacgccg
    19321 agcacctcct gcatgcggcc gaggccgcgc gcgcgcagat ccgccacggc ctgggcaacc
    19381 gcctgcactt cttcaccccc ggcatggaca cgcgcgcgcg gcgctggatc gcggtcgaga
    19441 gcgagctgcg ccacgcgctc gcgcgcggcg agctgcagct ctactaccag ccgatggtgt
    19501 gcgtgcgcga cggccgcgtg cgcaccgtgg aggcgctgct gcgctggaac agcccggcgc
    19561 tgggctgggt gtcgccggcg gagttcatcc cggtggccga ggagagcgag ctcatcgtgg
    19621 cgatcggcga ctgggtgctg gagaccgcat gccgtcaggt ccgccactgg caggacaccg
    19681 gcctgccgcc gatccgcgtg gcggtgaacg tctccgcaca ccagctcgcg agcggccgcc
    19741 tgcccgagcg cgtgcgcgag gtcctggagg gcacgggcat cgaccccggc caactcgaga
    19801 tcgagctcac cgagagcgcg atgatgacgg acagcgagca cagcgcgcgc caggtcgagg
    19861 cgatcagccg catgggggtg agcgtctcgc tcgacgactt cggcaccggc tactcctcgc
    19921 tcgcctacct cagccgcttc gcgctcacca agctgaagat cgaccgcagc ttcgtcgacg
    19981 gcctgacgag cgatccgaag agctcgatca tcgtggatgc aaccctgggc ctggcgcgcg
    20041 gcctcggcct gcgcgtggtc gccgagggcg tggagacgga ggcgcagcgc gcgctgctcg
    20101 ccgccgccgg ctgtgatgcg ctgcagggct acctgttcag cccgccggtg gcgccggccg
    20161 ccctcggcgc gctcatcgac cgcttcgcgc cggccgagcg ctacgcgaag ccgagggtgt
    20221 tcgccgtcag cgcctgatcg gggcgccgtc ggcactcagc gcggcggcgt gctcctggcc
    20281 tggcgcagcg accacaggct gaccagcgcg agcgcgccga cgatcagcgt catgccggcg
    20341 aactccgccg gtgtcgggcg ctcgccgagc tcgatccagc ccgcgagcgc gcccaccatc
    20401 gggatgccga gcgcggacag cccggccaca ccggtggaca agcgctgcag cacgaacagc
    20461 cacagcagcc aggccaggcc ggtggcgagc accgcgttga acaccagcgc gccccagaag
    20521 tagggcgtcg gatcgatcgg ccgcgagggg tgcagcagcg ccagcgcgca cagcgcgagc
    20581 gcgccgaaca gcatctgcca ggcggtgagc gagagcagat cgaagtcgtg cgcgcggcgc
    20641 atgcgcttgg cctgcaccga ggccaccgcc caggtcaccc caccggcgac cgcgagcagg
    20701 ttgctgaagg cgctgccgcc catcgcccaa ggctcgagca ccagcaccag gccgcaggcg
    20761 gcgatggcgt tggccgccca ctgcatgccg cgcacgcgct cgccgagcac aaaccaggcc
    20821 atcggcacca cccagaacgg catcgtatac accagcaccg cggtcttgcc ggccccgccg
    20881 gcgaccagcg cccactggat cagcgcggtg aaggcgccgg tctgcagcac gccgagcagc
    20941 gccacctggc gcacctgctg cagccccagc gggcgacgca gcacgaggag cacgacgaag
    21001 agcgtggcgg caccgagcac ggtgcggatc gccgagaagt cgaagggatc gacgtactgg
    21061 atgacctgct tcatgaccac ccagttgtag ccccagatca gcgacaggag cgcgagcgcg
    21121 agcagcgcca ggcgcggcga gccggatgcg gacatcggac ctccaaaagg aaaactccgc
    21181 ggcgccccgg gagggggccg cggccgaagg ggtgccgcca gggagacggc ggcgggcaac
    21241 agtgcgggat ggattatgcc ccggcctgcg ggcggcgaca gatgccggcg cggataagca
    21301 ttatccgcac cggcagtacg gcggatgcag cgctcaggcc ggctgcgccg ccacgacggg
    21361 cgccttgcgg ctcatcagcg caaggtgcag caccgcgccg agcagcgcac cgaacatcca
    21421 ccagccaccc ccccgcccgc cgtcttcgcc cccgctgccg agttacccga ctgggcgctg
    21481 cgctcggttg acctcgcgaa cccgctgctc gcgctcgaca acgggctgtg atcgccgcgg
    21541 aagcgccgca atcgcgcctg ccggcgctcc tacatgaacc ggcgcgattc cgtcccgtgg
    21601 aggagcggcg gcagccgcga atagggcggt ggggtggcga cgggcgatct cgcggttcga
    21661 cacgctgaaa tcgcgccagc cggcgctcct acatgaaccg gcgcggttcc gtcccttgta
    21721 ggagcggcgg cagccgcgaa tagggcggtg gggtggcgac gggcgatctc gtggctcgaa
    21781 tgcggtgggg acgcgtggcg tcacttacgc gatcgctgat gcgctgcatc agcccgcagc
    21841 gctgaccggg cgcgcggcgg ccgcctacac tccgcggccc catcgtgcgt ccctggaaga
    21901 cctcatgctg ctcggcctgt ccctgttcta cgtcggcgcg gtcctgatcc tcaacggcct
    21961 gtggatgctc ggccgcatcg gcgaccgcga gatcaccgtc atcaacctgt tcaccggcgg
    22021 gctgaccctg ctggtgtgcc tgcgcctggc tctgggcgcc gacgcggacg ccgcctcgat
    22081 ccgcggcgcg gcgttctcgc tgctgttctc cttgacctac ctgtgggtgg cctggaaccg
    22141 cctgaccggc ggcgacgggc gcgggctggg ctggttcagc ctgttcgtgg cgatcaccgc
    22201 ggtgccgatc gcggccgaca ccctgcgcgc agcggcgagc acctgggact ggtggctcgg
    22261 cctgtcgtgg gcggcgtggg cggtgctgtg gctgatgttc ttcctgctgc tggccctgca
    22321 caagccgatc gcacgcgcca ccgcatggat ggcgatcgtc cagggcgtgg gcaccgcctg
    22381 gctgccgggc tatctgctac tgaccggcac gctgggctga acgcaggcgc tcacaccgcg
    22441 ccgggctccg tatgctgcgc cgcaaaaata taaatttttg tatttcaggt attcgccccg
    22501 tccgctcctg tcgcgagagt gaatccctag actccatatc aagtcggtac ccgcccctgg
    22561 ccgcgcgctc cgtcgcggct cgacggccgg agcgcaccac caccccgacc cctgcacggc
    22621 gccgcgatga cccgggacca cccgggcggg acggcgccga agagacacac aaaacatgaa
    22681 ggagacgaac atgtccgacc tcgcactgca aggcggaggc gaccgggtcc atccggtcga
    22741 cgagaaactg cccggcgggc ggctcgccgc gctgggcatg cagcacgtac tggtgatgta
    22801 cgccggcgcg gtcgcagtgc cgctgatcgt ggggcgcgcg ctcggcctca gccccgagca
    22861 ggtcgccctg ctgatctccg ccgacctgtt ctgctgcggg ctggtgacgc tgatccagtc
    22921 gctcggcttc ggcaagtatt tcggcatcaa gctgccggtg atgatgggcg tgaccttcgc
    22981 cgcggtcggg ccgatggtgg cgatggccaa cgtgcagggc ggccccgatg gcgcgcgcgc
    23041 gatcttcggc gcgatcatcg gcgcaggcat cctgtcgatc ttcatcgcgc ccttcatgag
    23101 ccggctgctg cgcttcttcc cgccggtcgt caccggcacc atcatcgcca tcatcggcat
    23161 cagcctgatg cgggtgggcg tgggctgggc gatgggcggg ccggcccacc tcgcgcagag
    23221 cgtggatgtg cccaggctgg tgcagatggt ggacgtcgcc aaggccaagg cggccgaggc
    23281 gggcgtggag ctcgccaagc tgcccggccc cattccgatg gtgaacaacg ccggctacgg
    23341 cgccctcgac accatggccg tggcggcctt cgtgctggtg gtgatcctgc tgctggtgcg
    23401 ctatggacgc ggcttcgtcg ccaacatcgc ggtgctgctg ggcatcgtcg tcggctgcgt
    23461 ggtggcggtg gtgatgggca agatgcactt cgacaaggtc gccaaggccg actggttcga
    23521 tctggtgacg cccttcgcct tcggcatgcc gaccttcgac ccggtgatgg tgctgaccat
    23581 gaccctggtg atggtcgtgg tgatgatcga gtcggtgggc atgttcctgg cgctcggcga
    23641 gatcaccgac aagcgcatca gccgcaccga gctcgccgcc ggcctgcgca ccgacggcct
    23701 cggcaccctg atcggcggcc tcttcaacac cttcccctac accagcttct cgcagaacgt
    23761 gggcctggtg ggggtgaccg gggtgaagag ccgctgggtg tgcgtggcgg ccggcgtgat
    23821 catgatcgtg ctcggcatgc tgcccaaaat ggcggcgctg gtggagtcgg tgcccacctt
    23881 cgtgctcggc ggcgccggcc tggtgatgtt cgggatggtg gcggcgaccg gcatccgcat
    23941 cctctccaac gtcgacttcc gcggcaaccg caacaacctg tacatcgtcg cgctgtcgat
    24001 cggcttcggc ctggtgccgc tggtggcgcc gcgctggatg cagcacatgg cgcacagcct
    24061 gcatccgctg ctcgagtcgg ggatcctgct gacggcgatc tcggcggtgg tgctgaacct
    24121 ctacttcaac ggcggccgcg aggacaaggc gggcgcgatc gaggcggcga aggctgcaga
    24181 agcgcactga ccggggcacg gccggcaagc cggccgtgca ttcgcacggg gtgcaagcgg
    24241 aaagggggcc aacggccccc tttcttcgtt tccatcccag gcaatcggcc ctcggcacgc
    24301 cgccgcggcc cacccgggct cacttcatca tcgccaccag ccccagcgtg atcgacggga
    24361 aggcgaccag cagcagcagg cgcaacaggt cgatgccgac gaaggggaac agtccgcgga
    24421 agatcgcgcc cagcctgacg tgcggcaggg cggccttgag cacgaacacg ttcatgccga
    24481 tgggcggcgt gatcagcgcg atctcggtca ccaccaccac gatgatgccg aaccagacca
    24541 ggtcgaaacc gtggctcatc aggatgggga ggaagagggg gacgcagatc aggatgatcg
    24601 ccagcgactc catcacgcag ccgagcagca ggaagaggat caggatcgcc gccagggtct
    24661 ggtaggggcc gagtccggca tcctggacga gctccagcat gccttcgccc agtcccgaga
    24721 acgagatcag cttggcgaac agcagcgcgc cgaacagcac gctgtagagc atcaccgagg
    24781 tggtcgcggt ctcgacgaag atctgccgga agctcgccca gctcatccgc cgctgcgcga
    24841 tggacaggat cagcgccagg ccggcgccca ggcccgcggc ctcggtggcg gtgaagagcc
    24901 tgccatacag gccgccgatg atgaccacga agagcagggt gaagggccac acgccgcgca
    24961 gggagcggat cttttccgcg gtggtggtgc gttcgccgcg gggcgcgtcc tgcgggctga
    25021 tgcaggcgat ggcgtagacc acgcccaggt acatcaccag gccgaggatg cccgggatca
    25081 ctgcggcgac gaacaggtcg ccgatgttgg tctgggtcag gatgccgtag atcatcagga
    25141 tgatggacgg cgggatgagg atgccgagcg tgccgcccgc ggcgatggtg gccgaggcga
    25201 gctggtccga gtagccgtag cgcttcatgc tcgggtaggc gaccttcgac atcgtggcgg
    25261 cagttgcgag actggagccg cacaccgcgc tgaagccggc acaggtgacc atggtcgaca
    25321 gcgccagccc gccacgaacc gggccgagga aggcgttggc ggcgcggaac aggtcgtcgg
    25381 agatgcccga gcgggcgagg atgttgccca tcaggatgaa catcggcacc accgccagtt
    25441 catacgagaa cacggcttcg gagatcgtca tggggacgag cgagcgcgcg acgtcgaagc
    25501 ccatgacgac gctgatgccg gcgagcg
//
LOCUS       DAOTIN010000043        24212 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_2435_length_24212_cov_8.440204, whole genome shotgun sequence.
ACCESSION   DAOTIN010000043 DAOTIN010000000
VERSION     DAOTIN010000043.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 24212)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 24212)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24212
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2435_length_24212_cov_8.440204"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(209..1159)
                     /locus_tag="P5537_08425"
     CDS             complement(209..1159)
                     /locus_tag="P5537_08425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_041645937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HRV78106.1"
                     /translation="MKQTTFASLAFERKKKQTRRERFLAEMEKVVPWAALLAVIEPHY
                     PTTGRRGRPPMPLATMLRIYFMQQWYALSDPAMEDALYEVESMRRFAGLDLTNDAMPD
                     ETTILKFRHLLEKHALTSQMMNIINDTLEQRGLLLKGGTMVDATIIHAPPSTKNQERK
                     RDPEMHQTKKGNQWYFGMKVHVGADVNSGLVHTVSVTPANVSDINQLPHLVREDDRAV
                     FGDKGYVNNKLKRVARKAGLFWGVSLKASKQHPLTEANKRFNHKMSSIRARVEHVFRV
                     IKRQFGYTKVRYKGIAKNAAQVFSLIGLTNLYLARRALMS"
     gene            1276..2601
                     /gene="paaF"
                     /locus_tag="P5537_08430"
     CDS             1276..2601
                     /gene="paaF"
                     /locus_tag="P5537_08430"
                     /EC_number="6.2.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047475 - phenylacetate-CoA ligase
                     activity [Evidence IEA];
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate--CoA ligase"
                     /protein_id="HRV78107.1"
                     /translation="MPVKSPRPGDLDPIETASRDEITALQLQRLQWSVRHTYDNVAPY
                     RKRCEEAGVHPDDLKSLADLARFPFMTKTDLRDNYPFGLFAVPRDKVARLHASSGTTG
                     KSVVVGYTKNDLDNWADVVARSLRAAGVRAGDMVHNAYGYGMFTGGLGAHYGIERAGC
                     TVVPMSGGQTEKQVQQIMDFRPDAIMVTPSYSLVIAEEFERLKIAPEDISLKIGIFGA
                     EPWGEGMRAEIERKLGIDAIDIYGLTEVMGPGVASECIETKDGPVIWEDHFYPEIIDP
                     DTGEVLPDGEEGELVFTSLTKEAFPVIRYRTRDLTRLLPPTARSFRRIGKITGRSDDM
                     LIVRGVNVFPTQIEEQIMRDRRLSGNYQIVLTRDGHLDNVEIRVEVQRDLSGKLSRTE
                     TENIARELQHHIKTIIGISTKVNVMEFEAIPRTLTGKARRVIDQRPKQL"
     gene            2612..3817
                     /gene="pcaF"
                     /locus_tag="P5537_08435"
     CDS             2612..3817
                     /gene="pcaF"
                     /locus_tag="P5537_08435"
                     /EC_number="2.3.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA];
                     GO_process: GO:0019619 - 3,4-dihydroxybenzoate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoadipyl-CoA thiolase"
                     /protein_id="HRV78108.1"
                     /translation="MTQAFICDAIRTPIGRYGGTLAAVRADDLGAVPLKALMARNPQV
                     DWAAVEDILYGCANQAGEDNRNVARMSGLLAGLPIEVPGTTVNRLCGSGMDAIGLAAR
                     SIKADDTELMIAGGVESMSRAPFVMGKAESAFSRSAAIYDTTIGWRFINPLMKKLYET
                     HSMPQTADNVAADFNIARADQDAFALRSQQRWAAAHAAGRFKDELVPVEIPRKKGEPI
                     VFDTDEHPRPDTTLEMLAKLKGVNGPELSVTAGNASGVNDGACALLLASEAAAARHGL
                     TPRARVVAMATAGVAPRIMGFGPAPAVRKVLAKTGLSLDQMDVIELNEAFAAQALAVL
                     RDLGLADDEARVNPNGGAIAMGHPLGMSGARLVTTAAYELQRRNGRYALCTMCIGVGQ
                     GIAMIIERV"
     gene            3834..4619
                     /locus_tag="P5537_08440"
     CDS             3834..4619
                     /locus_tag="P5537_08440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HRV78109.1"
                     /translation="MTYETLAIERRGAVATIWMDRPEVFNAFNEQLIAELAAACAELD
                     ADASVRVVVLAGRGRHFSAGADLNWMRRASDSTEAENLADSRKFAAMLRTLSAMSKPT
                     IARVQGAALGGGTGLTAACDMAIAADDASFATSEVKFGIIPAVISPYVLRAIGPRHAL
                     RYFQSAERFGAAEAKAMGLVGEVVAVDELDAAVDRLVQALLACGPQAQIAAKQLIAAL
                     AGRPIDDAVAEETAGRIARQRATEEAREGFAAFFDKRSPAWMQ"
     gene            4736..5743
                     /gene="paaA"
                     /locus_tag="P5537_08445"
     CDS             4736..5743
                     /gene="paaA"
                     /locus_tag="P5537_08445"
                     /EC_number="1.14.13.149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097266 - phenylacetyl-CoA 1,2-epoxidase
                     activity [Evidence IEA];
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,2-phenylacetyl-CoA epoxidase subunit A"
                     /protein_id="HRV78110.1"
                     /translation="MYTQAMDIPDDSGKKLAAVSNAPSEQEAAFEARIDADGRIEPQD
                     WMPEAYRKTLVRQISQHAHSEIVGMLPEGNWISRAPSLKRKAILIAKVQDEGGHGLYL
                     YSAAETLGTSRDQMLEGLHSGKAKYSSIFNYPTLNWADVGVIGWLVDGAAIMNQVPLC
                     RCSYGPYARAMVRVCKEESFHQRQGYEALLVMMKGTDEQRAMVQDAVNRYWWKCLAMF
                     GPPDADSPHSAQGMRWGIKRISNDDLRQKFIDATVPQAKVLGVTLPDPALKWNEARGH
                     YDYGQIDWAEFWNTVEGNGPCNKERLATRVKAHNDGQWVRDAAQAYARKQKERALKEA
                     A"
     gene            5740..6036
                     /gene="paaB"
                     /locus_tag="P5537_08450"
     CDS             5740..6036
                     /gene="paaB"
                     /locus_tag="P5537_08450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,2-phenylacetyl-CoA epoxidase subunit B"
                     /protein_id="HRV78111.1"
                     /translation="MNTPALKDWPLWEVFVRSKQGLEHKHCGSLHAADAAQALHMARD
                     VYTRRQEGVSIWVVPSVAITASNPDDKGELFDPAADKIYRHPTFYEIPEEVGHM"
     gene            6036..6818
                     /gene="paaC"
                     /locus_tag="P5537_08455"
     CDS             6036..6818
                     /gene="paaC"
                     /locus_tag="P5537_08455"
                     /EC_number="1.14.13.149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate-CoA oxygenase subunit PaaC"
                     /protein_id="HRV78112.1"
                     /translation="MSTPIDYLLHLADNAVVLGQRNAEWCGHGPILEEDMALANVSLD
                     LIGQARLLYQRAAELMGGDATEDKLAYFRGPHEFRNYTLLELPHHGALVGYAAADRDY
                     ATTIVRNFLYSALMVHVWDGLQQSADPALAAIAAKSLKETSYHLHHSRDWLVRMGDGT
                     EESHARAQAAVNHLMPYTEEFWTTSPAEGAAVAAKVAIDVWALRPAWDALVNDALAEA
                     TLTRPNFHGYITEGKIGLHSEHLSYLLGEMQGLARAHPGATW"
     gene            6832..7347
                     /gene="paaJ"
                     /locus_tag="P5537_08460"
     CDS             6832..7347
                     /gene="paaJ"
                     /locus_tag="P5537_08460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate-CoA oxygenase subunit PaaJ"
                     /protein_id="HRV78113.1"
                     /translation="MSSVVDKVWATLEPLTDPEIPVVTLRELGILRDVRETPTGLEVV
                     ITPTYSGCPAMGQIEDDVRASLEQAGIEARVITQLAPAWTTDWMSDEAKEKLRAYGIA
                     PPHRTCGSRAGAGEVSVLKFVRRQPTEPVACPQCGSTHTVVTSEFGSTACKALYKCLD
                     CQEPFDYFKPY"
     gene            7366..8463
                     /locus_tag="P5537_08465"
     CDS             7366..8463
                     /locus_tag="P5537_08465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /protein_id="HRV78114.1"
                     /translation="MSAPRFQEVAVKRVSPEAAGAVAITFAIPEAERERFAFEPGQFL
                     TLRATIDGQDVRRNYSISSPRSRLTREGELEIGIRPVEGGLFSNWAARAIKAGDTLQV
                     MPPDGRFVVKKKRAIHRVGFAAGSGITPILSIAATTLEEQPDSKFTLIYGNRRMSTVM
                     FNEDLQDLKDRFRDRLTMIHVLSRQAQEVDLLQGRIDGAKVRAIIDALLPVGSMDEVF
                     ICGPDEMITATENALVEAGVPADRIRTERFTTHLPAGAHPVGVSSTAEAAEAATKDIT
                     MVLVLDGKEHEIAIGPDEHLLDAGLNAGLDLPFSCKAGVCCTCRAKVTEGEVVMDKNF
                     TLEADEVAQGYVLSCQARATTKRLKISFDER"
     gene            8641..11298
                     /locus_tag="P5537_08470"
     CDS             8641..11298
                     /locus_tag="P5537_08470"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HRV78115.1"
                     /translation="MAGSHALGTAFEPSSIAVIGASDAPGSVGRVIFRNLVEGGYRGA
                     LYAVNPKYDSIQDHPCHRSVEDIGRPVDLAIIATPARMLHTVTAQCGRSGVRNAVIVS
                     ASGNALERRIIETARESRLRLIGPGSLGIARPGSGINAALTRIAVKPGEIALVSQSGA
                     MCSVVLDWALTNDVGFSSVISLGGTVDIDYGETLEYLIHDAQTRYILLYVDHVRNARR
                     FMSALRSASRVKPIILLKAGRHGRGDNNAPEVDNAGLADVVFDAAMRRAGVVRVQNID
                     QLFFAAKALSCGFRPREDSLAIVSNGSGPADLAADRAKDLGTELVSLGSATVATLERL
                     GGRERRSHNPLDLGGDASAKLYRDAILALAEDAAVSNLLVILSPHALVDPVEVAQDII
                     DLAAQVRLKLCCCWMGGGQVAEARTLLAQAGLPVFSSPEAAIELFHNISRFHHSQTLL
                     LQTAGGSATAYRRTGGARVLIETLLNQRRHVLSAMESKALLRSFGIPVTHTTVARDAT
                     EALFVAEQTGFPVALKVDAPELASKSESGGVRLNLNTTEAVWSAYHDIIETVRQRRPE
                     ARINGVSIEPYLYRPQSRAFSIQVHRDAIFGPVISLGAQDASAPRTFALPPLNAVLAR
                     DLIDSATPVAAQGPRSRAGALNRAAIEQVLVSVSDLVCELPWVRELAIDPLLIDGDGA
                     IAADARVVIDQGLPAGSDRYAHMAIHPYPLHLIQDWKVGDGRPVRTRPVRPEDAKLLL
                     GFFDALSPETRFMRFMEELDELSPAMVARFTQIDYDCEMALIATTIADKDAERMIGIA
                     RYALAADGESVEFALVVSDDWQRHGLGRRLMGALIEVARNKGYRNIFGDVLGNNAKML
                     RLMHSLGFMVQPHPEESSLRRVVKVLHGN"
     gene            complement(11326..12048)
                     /locus_tag="P5537_08475"
     CDS             complement(11326..12048)
                     /locus_tag="P5537_08475"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HRV78116.1"
                     /translation="MISRFHFPDRLPAGGEVALPDALAHHALRVLRLRDGEAVVLFDG
                     SGGEVEARLAVRGKAVFAQLGEARAVERESPLRIVLVQALASGDKMDWVVQKAVELGA
                     HAVQPVQAERSVLRLAGERADKRVAHWQQVAVAACEQCGRNRVPEIRPLQALAPWLGA
                     HRDALNYVLAPGGAAGFADEPEPKDVVHLLVGPEGGWSEVEIAAFDAAGCRPVRLGPR
                     VLRTETAGLAAVAALQARWGDF"
     gene            12100..12909
                     /locus_tag="P5537_08480"
     CDS             12100..12909
                     /locus_tag="P5537_08480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase"
                     /protein_id="HRV78117.1"
                     /translation="MPTAAHRLARARALESMVRDIARAEILPRYLKSARNRKADGSLF
                     TEADMASQQRFSEALPAFLPGAVLGEEMTAAEQAALWKEGARGLWCIDPIDGTTNFAN
                     GIPLFAVSIAYLIDHEPVIGVVYNPITDESFYAARGAGAFLNGTELPLRAGATELRDA
                     VAGVDFKRISHHLGDELAVRPPYYSQRNFGSSALEWCFVAAGRLDVYLHGGQMLWDYA
                     AGRLILAEAGGVAEALDGGVLMSGPAIKRGVIAATSPALFTEWSAWVKARS"
     gene            12980..13855
                     /locus_tag="P5537_08485"
     CDS             12980..13855
                     /locus_tag="P5537_08485"
                     /EC_number="2.7.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008974 - phosphoribulokinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HRV78118.1"
                     /translation="MSMKHPIIAVTGSSGAGTTTVKHTFEAIFHRENVNAAIVEGDSF
                     HRYTRAEMKQLIEEAEREGRRGISHFGPEANLLSELESLFRAYGDAATGRRRYYIHNE
                     AEAMRWNLPLGTFTEWEDLPVGTDCLFYEGLHGALVTDAVDIAGHVDLLIGVVPTINL
                     EWIQKLHRDTKMRGYTAEAVQDTILRRMHDYVHYIVPQFARTHINFQRVPVVDTSNPF
                     IARDVPTQDESMVVIRFKDPRGVDFPYLLRMIHDAFMSRANTIVIPGGKLDLAMQLIL
                     TPLIWKLMERRRQWV"
     gene            14245..16260
                     /gene="tkt"
                     /locus_tag="P5537_08490"
     CDS             14245..16260
                     /gene="tkt"
                     /locus_tag="P5537_08490"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HRV78119.1"
                     /translation="MQSTRNVQPPVFNPITGAIRALAMDAVQQANSGHPGAPMGMAEI
                     AEVLWRHHLKHNPANPRWADRDRFVLSNGHGSMLIYALLHLTGYDLPIEELKRFRQLH
                     SKTPGHPEYGYAPGIETTTGPLGQGITNAVGMALAEKILAAEFNRPGHDIVNHNTYVF
                     LGDGCLMEGISHEACSLAGTWGLGKLVAFYDDNNISIDGHVQGWFTDDTPKRFEAYGW
                     QVIRDVQGHDPVAIEAAIQQAKANTAQPTLICCKTIIGAGAPNKQDSHDVHGAPLGAA
                     EIEAARAHIGWNHPPFHVPADIYAAWDARTKGASLEAQWNAAFAAYRAAHPELAAEFE
                     RRMAGNLPADWDAHVAAVLAKVTDKAETIATRKASQNAIEAYAPKLPELLGGSADLAG
                     SNLTLWSGAKGVGKTSGGNYVYYGVREFGMAAIANGVALHGGLIPYTATFLMFSEYAR
                     NALRMAALMKVRQIFVFTHDSIGLGEDGPTHQPVEQTATLRLIPNMDVWRPCDTTESA
                     VAWANAIERKDGPTSMCFSRQNLPFQARSAEQVAAIRKGGYVLSEAAGGKPQAVILAT
                     GSEVALAMAAQKTLADQGVAVRVVSMPSTNVFDRQDAAYKASVLPAGLPRVAVEAGTT
                     DGWYKYVGLEGRVIGIDRFGESAPAGELFKYFGITADAVVQAVKSVL"
     gene            16398..17426
                     /gene="gap"
                     /locus_tag="P5537_08495"
     CDS             16398..17426
                     /gene="gap"
                     /locus_tag="P5537_08495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0019682 - glyceraldehyde-3-phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HRV78120.1"
                     /translation="MSIKVAINGFGRIGRCTLRAIYEQGLQNEFEVVAINASGDLATN
                     AHLLKYDTTHGRFATSVETEGEDCIIIDGKKIPFYSTKDPKGVNWGSHGVDVLLECTG
                     AYTTKAKAQALLDQGARRVLISAPGGDDVDTTIVMGVNEEVLRGDMTVVSNASCTTNC
                     LAPVAKILADSVGIKQGLMTTIHAYTNDQVTVDVRHKDLRRARAAAANIIPTKTGAAK
                     AVGLVLPQLVGKVDGFALRVPTINVSLVDLTFTAERATTKEEINALMTAAANGPLKGI
                     LAVNTEPLVSSDFNHTTVSSTFDATQTRVIKGEDGSVLVKVLAWYDNEWGYSCRMLDA
                     ARAFCNAK"
     gene            17489..18673
                     /locus_tag="P5537_08500"
     CDS             17489..18673
                     /locus_tag="P5537_08500"
                     /EC_number="2.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015434619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HRV78121.1"
                     /translation="MQVKKLTDLDVRGKKVFIRADLNVPQDDAGNITEDTRIRASLPS
                     IQYCLDNGAAVMVTSHLGRPTEGTVGPDDTLAPVAVRLGQLLHRPVRLVADWVEGGFE
                     LKPGEVVLLENCRCNKGEKKDNEELAKKMAALCDVYVNDAFGTAHRAEATTHGIARFA
                     PVACAGILMGAEIDALGKALQSPQRPLVAIVGGSKVSSKLTILKSLADKVDQLIVGGG
                     IANTFLLASGKRIGESLAEPELVKEAQAIMDMMKARGAEVPLPVDVVVADEVSALARA
                     NRIPVEEVGAHDRILDVGPKTAAKLSEIIANAGTIVWNGPVGVFELPQFAGGTKMMAS
                     AIAHSEAFSIAGGGDTLAAIAKFHIAEDVGYISTGGGAFLEFLEGKTLPAIAALEARF
                     KD"
     assembly_gap    18729..18828
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(18998..19735)
                     /locus_tag="P5537_08505"
     CDS             complement(18998..19735)
                     /locus_tag="P5537_08505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase iron-sulfur subunit"
                     /protein_id="HRV78122.1"
                     /translation="MSRRLKISIFRHNPRDPQSAPRLVDYELDEQPGMTLFIALNAIR
                     DTQAPDLNFDFVCRAGVCGACAMVIDGRPGLACRTLTSTLPAAFSLYPLPVFRLVADL
                     SVDVGSWMRELAERLQTWVHLDAEPDLDRLEARMEPALAEEVYELDRCIECGCCIAAC
                     ATAQMREGFVGAVGLNKIARFRLDPADTRDDADFYELVGNDEGIFGCMSLLACNDLCP
                     KELPLQTQLAWLRRKMAGQGVRWLRRG"
     gene            complement(19732..21735)
                     /locus_tag="P5537_08510"
     CDS             complement(19732..21735)
                     /locus_tag="P5537_08510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase flavoprotein subunit"
                     /protein_id="HRV78123.1"
                     /translation="MRIEYTDVLVAGGGLAGLRTAVGAARRGLRVEVLSLVPAKRSHS
                     VAAQGGMQASLGNAFKGMGDNEDVHFGDTVRGSDWGCDQLVARMFAHMAPKAVRELAA
                     WGVPWNRVQRGAHEAVINGERVTLTERDEAHGLITARDFGGTRKWRTCYTADGTGHTM
                     LYALGDRAVAEGIPVRNRSEAVALIHDGGRCQGAVVRDLETGELYAILAAATVIATGG
                     FGRIWGISTNALINEGMGAAIALETGVARLANMEAVQFHPTAIVPAGILVTEGCRGDG
                     GLLRDVDGHRFMPDYEPEKAELASRDVVSRRMAEHMRRGKGVKSAAGEHLWLDIAVLG
                     AAHIDHKLREVKDICRHFLGIDPARDWIPVRPTQHYSMGGIRTDHRGESPSLRGLFAV
                     GEAACWDLHGFNRLGGNSLAETVVAGMLVGEYVADFVESHAGALQFSPGLAREFVGRE
                     RAALEAIAARPAPAAGGDSATSLRREMEATMTEHVGLFRNEAGLRSAVARLADLHARA
                     LRVGIASSHLDANPELVAAYRLPRMLALALCAAQGALERRESRGAHAREDYPARNDRD
                     WLRRTLAWWPTGASAPVLEYEPITVEHMELPPGFRGYGTRNIVEHPATALREAEIESI
                     RARLEGAGRTPLQAALLDFRMRLPERYRGDNERLADIEEGAPR"
     gene            complement(21732..22496)
                     /locus_tag="P5537_08515"
     CDS             complement(21732..22496)
                     /locus_tag="P5537_08515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase cytochrome b subunit"
                     /protein_id="HRV78124.1"
                     /translation="MTLPRSRAASAASLWPARLDLLQALSGLALALFMWLHMGFVSAI
                     LISADFAWSVARFFEGYFFLPRPQAWLVLAFVAAIAALFALHALLALRKFPADWRQYR
                     IAARHGSRLRHGDTTLWFVQVATGFAMFFLAPVHLYAMFTHPDLIGPFESADRVWTGG
                     FWPLYLALLFAVEVHGSVGLYRLAVKWGWFEGRDARASRRRLKWAMWGLIAFLLTLGL
                     TTLLAEIRMGIEHAPRAGERYVPTWQRGTTAAEEAR"
     gene            complement(22681..23796)
                     /locus_tag="P5537_08520"
     CDS             complement(22681..23796)
                     /locus_tag="P5537_08520"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HRV78125.1"
                     /translation="MAPPVKASRRAAAMAVSSVALCMLSASAHALPSSLYVFGDSLSD
                     TGNLYAWTGQANPVTGGLAIPVSPPYAQGTFTNGPVYAERLWDQLSLPGELAPAALPG
                     GTNFAVGGARSRYHSFDVDANGLPPLAWPANFASFSLTGQFGRYRDGLAGGAADASAL
                     YLVWAGANDLQDVLRLAQVSGPDAAGARLVEAAGDVAGVIGGLVGLGARQFMVPTVPD
                     IGAMPVVAAFGAQAQEAARQYSIAFNQAIDQALRSFAGVPELEVLRFDAFGLLDEVVR
                     SPAANGFSDIETACLQGLYLAPTPGAPAPTICANPDEHLFWDVVHPSAAAHVILADAM
                     YRQVRAAFVPEPSLPALLVVGVFFLGIFRRPRTASLV"
     gene            23972..>24212
                     /locus_tag="P5537_08525"
     CDS             23972..>24212
                     /locus_tag="P5537_08525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HRV78126.1"
                     /translation="MSRHTKIVATLGPASSDLLTLERMVHAGLDVVRMNFSHGKPEDH
                     VARAETIRDASARAGRPIGILADLQGPKIRVGKFEE"
BASE COUNT         4016 a         8974 c         7776 g         3346 t
ORIGIN      
        1 ctggccgagc gtgacgaaca gcggcccgat ggaggccaga agttcattgc ctaaggaacc
       61 cctgatcaac tgatgttctg agcacgctca cccaagccaa ccgctttcgc cgactccgat
      121 gatcgatttt tccgcgccta ccgctgtttt tcgaggcctt ttcggccccg agcacccgtt
      181 ttcgggtgca gcgggcggat ttcgcccatc aactcatcaa ggctcgcctc gccaagtaaa
      241 ggttggtcag tccgatcagc gagaacacct gggcggcgtt cttcgcgatc cccttgtagc
      301 gcaccttcgt gtagccgaac tggcgcttga tgacgcggaa gacatgctcc acccgcgcgc
      361 ggatcgagga catcttgtgg ttgaaacgct tgttcgcctc ggtcagcggg tgctgcttgc
      421 tggccttgag cgacacaccc cagaacaggc ccgccttgcg cgcgacgcgc ttgagcttgt
      481 tgttcacgta gcccttgtcg ccgaacaccg cccggtcatc ctcacgcacc aggtgcggca
      541 actggttgat gtccgagaca ttggcaggcg taaccgaaac ggtatgcaca agcccggaat
      601 tgacgtcggc gcccacatgg accttcatgc cgaagtacca ctggttgccc ttcttggtct
      661 gatgcatctc agggtcgcgc ttgcgttcct ggttcttcgt cgagggcggc gcatggatga
      721 tcgtggcgtc gaccatcgtg ccgcccttga gcaagagccc acgttgctcg agcgtgtcgt
      781 tgatgatgtt catcatctgg gacgtcagcg cgtgcttctc gagcaggtgg cgaaacttga
      841 ggatcgtcgt ctcgtcgggc atcgcgtcgt tggtcaggtc gagccccgca aagcggcgca
      901 tcgactcgac ctcgtagagc gcatcttcca tcgccggatc cgacagcgcg taccactgct
      961 gcatgaagta gatccgcagc atcgtcgcaa gcggcatcgg cggacgcccg cgtcggcccg
     1021 tcgtcgggta gtgcggctcg attactgcca gcagcgctgc ccaaggcacg accttctcca
     1081 tctcggccag gaagcgctcc cggcgagtct gtttcttctt ccgttcgaaa gccagcgagg
     1141 cgaaggtcgt ttgcttcatg gtggcagcgc gggttatgac ttcagtattt taccggctct
     1201 gaatagatca gagcttccct agacgggtcc gcgcggcccc acgcacaacc agagagagac
     1261 agaggagacc acaccatgcc cgtgaagagc ccccgccccg gcgacctcga cccgatcgag
     1321 accgccagtc gcgacgagat caccgcgctg cagctgcaac gcctgcagtg gtccgtacgc
     1381 cacacctacg acaacgtcgc gccctaccgc aagcgctgcg aggaagcggg cgtacatccc
     1441 gacgacctca agtcgctcgc cgacctggcc aggttcccct tcatgaccaa gacggacctg
     1501 cgcgacaact accccttcgg cctcttcgcc gtgccgcgcg acaaggtcgc ccgcctgcac
     1561 gcctcgagcg gcaccaccgg caagtcggtg gtggtcggct acacgaagaa cgacctcgac
     1621 aactgggccg acgtcgtcgc acgttcgctg cgcgcggccg gcgtgcgtgc gggcgacatg
     1681 gtgcacaacg cctacggcta cggcatgttc accggcggcc tcggcgccca ctacggcatc
     1741 gagcgcgccg gctgcaccgt ggtgccgatg tccggcggcc agaccgagaa gcaggtccag
     1801 cagatcatgg acttccgccc cgacgcgatc atggtcacgc cgtcctactc gctggtcatc
     1861 gccgaggagt tcgaacgcct gaagatcgcc ccggaagaca tctcgctcaa gatcggcatc
     1921 ttcggcgccg agccctgggg cgagggcatg cgcgccgaga tcgagcgcaa gctcggcatc
     1981 gacgccatcg acatctacgg cctcaccgag gtcatgggcc cgggcgtggc cagcgagtgc
     2041 atcgagacca aggacggccc ggtgatctgg gaagaccact tctaccccga gatcatcgac
     2101 cccgacaccg gcgaggtgct gcccgacggc gaggaaggcg agctggtgtt cacctcgctg
     2161 accaaggagg ccttcccggt catccgctac cgcacccgcg acctcacccg cctgctgccg
     2221 ccgaccgcgc gctcgttccg ccgcatcggc aagatcaccg ggcgctccga cgacatgctg
     2281 atcgtgcgcg gcgtgaacgt gttcccgacc cagatcgagg agcagatcat gcgcgaccgc
     2341 cgcctgtcgg ggaactacca gatcgtgctg acgcgcgacg gccacctcga caacgtcgag
     2401 atccgcgtcg aggtccagcg cgatctgtcg ggcaagctca gccgcaccga gaccgagaac
     2461 atcgcgcgcg agctgcagca ccacatcaag accatcatcg gcatcagcac caaggtgaac
     2521 gtgatggagt tcgaagccat tccgcgcacg ctgaccggca aggctcgccg cgtcatcgac
     2581 cagcgcccga agcagctgta aggagcgcac gatgactcaa gccttcattt gcgacgccat
     2641 ccgcaccccc atcggccgct acggcggcac cctggcggcg gtgcgcgccg acgacctcgg
     2701 cgccgttccc ctcaaggcgc tgatggcgcg caacccccag gtcgactggg ccgcggtgga
     2761 agacatcctc tacggctgcg ccaaccaggc cggcgaggac aaccgcaacg tcgcgcgcat
     2821 gtccggcctg ctcgccgggc tgccgatcga ggtgcccggc accacggtga accgcctgtg
     2881 cggctcgggc atggacgcca tcggcctggc cgcacgctcg atcaaggccg acgacaccga
     2941 gctgatgatc gccggcggcg tcgagagcat gtcgcgcgcg cccttcgtga tgggcaaggc
     3001 cgagtcggcc ttctcgcgca gcgcggcgat ctacgacacc accatcggct ggcgcttcat
     3061 caacccgctg atgaagaagc tgtacgagac gcactcgatg ccgcagaccg cggacaacgt
     3121 cgccgccgac ttcaacatcg cgcgcgccga tcaggacgcc ttcgcgctgc gatcgcagca
     3181 gcgctgggcg gcggcccacg ccgccggccg cttcaaggac gagctggtgc cggtcgagat
     3241 cccgcgcaag aagggcgagc cgatcgtctt cgacaccgac gagcacccgc gccccgacac
     3301 cacgctggag atgctggcca agctcaaggg cgtcaatggc cccgagctca gcgtcaccgc
     3361 cggcaacgcc tcgggcgtca atgacggcgc ctgcgcgctg ctgctggcct ccgaggccgc
     3421 cgccgcccgg catggcctga ccccgcgcgc gcgcgtcgtc gccatggcca ccgccggcgt
     3481 ggcgccgcgc atcatgggct tcggcccggc gcccgcggtg cgcaaggtgc tcgccaagac
     3541 cggcctcagc ctcgaccaga tggacgtcat cgagctcaac gaagccttcg ccgcgcaggc
     3601 gctcgccgtg ctgcgcgacc tcggcctggc cgacgacgag gcgcgcgtga accccaacgg
     3661 cggcgccatc gccatgggcc acccgctcgg catgagcggc gcgcgcctgg tcaccaccgc
     3721 ggcctacgag ctgcagcgcc gcaacggccg ctacgcgcta tgcaccatgt gcatcggcgt
     3781 cggccagggc atcgcgatga tcatcgagcg cgtctgaggc acgggacagc gacatgacct
     3841 acgaaaccct cgccatcgag cgccgcggcg ccgtcgccac catctggatg gatcggccgg
     3901 aggtgttcaa cgccttcaac gagcagctca tcgccgagct cgctgccgcc tgcgccgaac
     3961 tcgacgccga cgccagcgtg cgcgtggtgg tgctcgccgg tcgcggcagg cacttctcgg
     4021 ccggcgccga cctcaactgg atgcgtcgcg cctcggacag caccgaggcc gagaacctcg
     4081 ccgactcgcg caagttcgcc gccatgctgc gcaccctgtc ggcgatgtcc aagccgacca
     4141 tcgcgcgcgt gcagggcgcc gcgctcggtg gcggcaccgg cctgaccgcg gcctgcgaca
     4201 tggcgatcgc ggcggacgac gccagcttcg cgacctccga ggtcaagttc ggcatcatcc
     4261 ccgcggtgat cagcccctac gtgctgcgcg ccatcggccc gcgccacgcc ctgcgttact
     4321 tccagagcgc ggagcgcttc ggcgccgccg aggccaaggc catgggcctg gtcggcgagg
     4381 tcgtcgcggt agatgaactc gacgctgcgg tcgatcgcct cgtgcaggcg ctgctcgcct
     4441 gcggaccgca ggcccagatc gccgccaagc agctgatcgc cgcactggcc ggacgtccga
     4501 tcgacgacgc cgtcgccgag gagaccgccg gtcgcatcgc gcgccagcgc gccaccgagg
     4561 aggcgcgcga aggcttcgcc gccttcttcg acaagcgctc gccggcctgg atgcaatgaa
     4621 cacccgccac gccccgggcg tggcggacct ttgaggagga ggcggggtca cagccatgcg
     4681 caccccgcgt tccgcaccgg tatttcccgg tgcggtgttt gctaggagga aacacatgta
     4741 cacccaggca atggacattc cggacgattc cgggaagaaa ctggccgcgg tctccaacgc
     4801 cccgagcgag caggaagccg ccttcgaggc ccgcatcgac gccgacggcc gcatcgagcc
     4861 gcaggactgg atgcccgagg cctaccgcaa gaccctggtg cgccagatca gccagcacgc
     4921 ccacagcgag atcgtcggca tgctgccgga gggcaactgg atctcgcgcg ccccgagcct
     4981 caagcgcaag gccatcctga tcgccaaggt ccaggacgag ggcggccacg gcctctacct
     5041 gtactcggcc gccgagacgc tcggcaccag ccgcgaccag atgctcgaag gcctgcactc
     5101 gggcaaggcc aagtacagct cgatcttcaa ctacccgacc ctgaactggg ccgacgtcgg
     5161 cgtgatcggc tggctggtcg atggcgcggc gatcatgaac caggtcccgc tgtgccgctg
     5221 ctcctacggc ccctatgcgc gcgccatggt gcgcgtgtgc aaggaggaat ccttccacca
     5281 gcgccagggc tacgaggccc tgctggtgat gatgaagggc accgacgaac agcgcgcgat
     5341 ggtgcaggac gcggtcaacc gctactggtg gaagtgcctg gccatgttcg ggccgccgga
     5401 tgcggacagc ccgcacagcg cgcaaggcat gcgctggggc atcaagcgca tcagcaacga
     5461 cgacctgcgc cagaagttca tcgacgccac cgtgccgcag gccaaggtgc tgggcgtgac
     5521 cctgcccgac cccgccctga agtggaacga ggcgcgcggc cactacgact acggccagat
     5581 cgactgggcc gagttctgga acaccgtcga aggcaacgga ccgtgcaaca aggagcgcct
     5641 agccacccgg gtcaaggcac acaacgatgg gcagtgggtc cgcgacgcgg cccaggccta
     5701 tgcccgcaag caaaaagaac gcgcactgaa ggaggcagca tgaacacccc cgcactcaag
     5761 gattggcccc tctgggaagt cttcgtccgc agcaagcaag gcctcgagca caagcactgc
     5821 ggcagcctgc acgcggccga cgccgcccag gccctgcaca tggcgcgcga cgtctacacc
     5881 cgccgccagg aaggcgtgag catctgggtg gtgccctcgg tggcgatcac cgccagcaac
     5941 ccggacgaca agggcgaact cttcgacccc gccgccgaca agatctaccg ccatccgacc
     6001 ttctacgaga tccctgaaga agtggggcac atgtaatgag cacgccgatc gactacctgc
     6061 tgcacctggc cgacaacgcc gtcgtgctcg gccagcgcaa cgccgaatgg tgcgggcacg
     6121 gccccatcct cgaggaagac atggcgctgg ccaacgtcag cctcgacctc atcggccagg
     6181 cgcgcctgct gtaccagcgc gccgccgagc tgatgggcgg cgacgccacc gaggacaagc
     6241 tggcctactt ccgcggcccg cacgagtttc gcaactacac gctgctggag ctcccgcacc
     6301 acggcgcgct ggtgggctac gccgcggccg accgcgacta cgccaccacc atcgtgcgca
     6361 acttcctgta ctcggcgctg atggtgcacg tttgggacgg gctgcagcag tccgccgacc
     6421 ccgccctcgc cgcgatcgcc gccaagtcgc tcaaggagac cagctaccac ctgcaccact
     6481 cgcgcgactg gctggtgcgc atgggcgacg gcacagagga atcgcacgcc cgcgcgcagg
     6541 cggcggtgaa ccacctcatg ccctacaccg aggagttctg gaccaccagt ccggccgagg
     6601 gcgccgcggt ggcggccaag gtcgcgatcg acgtgtgggc gctgcgcccg gcctgggacg
     6661 cgctggtgaa cgacgcgctc gccgaagcca cgctgacccg cccgaacttc cacggctaca
     6721 tcaccgaggg caagatcggc ctgcactccg agcatctgag ctacctgctc ggcgagatgc
     6781 aggggctggc ccgcgcccac ccgggcgcca cctggtaaaa ggacgaaggc catgagcagc
     6841 gtcgtggaca aggtctgggc caccctcgag cccctgacgg acccggagat cccggtggtg
     6901 accctgcgcg agctgggcat cctgcgcgat gtgcgggaga cgccgacggg tctcgaggtt
     6961 gtcatcaccc cgacctacag cggctgcccc gccatggggc agatcgagga cgacgtgcgg
     7021 gcgagcctgg aacaggccgg catcgaggcg cgggtgatca cccagctcgc gccggcctgg
     7081 accaccgact ggatgagcga cgaggccaag gagaagctgc gcgcctacgg catcgccccg
     7141 ccgcaccgca cgtgcggcag ccgcgccggt gccggcgagg tcagcgtgct caagttcgtg
     7201 cgccggcagc cgaccgagcc ggtcgcctgt ccgcagtgcg gctccaccca caccgtcgtc
     7261 acctccgagt tcggttccac ggcctgcaag gcgctgtaca agtgcctcga ctgccaggag
     7321 cccttcgact atttcaaacc ctattaagag ccggagccag acgccatgtc agccccccgt
     7381 ttccaagaag tcgccgtcaa gcgcgtgagc cccgaggctg ccggcgcagt ggcgatcacc
     7441 ttcgccatcc ccgaggccga gcgcgaacgc ttcgccttcg agccgggcca gttcctcacc
     7501 ctgcgcgcca ccatcgacgg ccaggacgtg cgccgcaact attcgatcag cagcccgcgc
     7561 agccgcctga cgcgcgaggg cgagctcgag atcggcatcc gcccggtcga aggcgggctg
     7621 ttctcgaact gggccgcgcg cgccatcaag gccggcgaca ccctccaggt gatgccgccc
     7681 gacggccgct tcgtggtgaa gaagaagcgt gccatccacc gcgtcggctt cgccgccggc
     7741 tcggggatca cgccgatcct ttcgatcgcg gccacgacgc tggaagagca gcccgactcc
     7801 aagttcacgc tgatctacgg caaccgccgc atgtccacgg tgatgttcaa cgaggacctg
     7861 caggacctca aggaccgctt ccgcgaccgc cttaccatga tccacgtgct gtcgcgccag
     7921 gcccaggaag tggacctgct gcagggccgc atcgacggcg ccaaggtgcg tgcgatcatc
     7981 gacgccctgc tgccggtcgg cagcatggac gaggtcttca tctgcggccc ggacgagatg
     8041 atcaccgcca ccgaaaacgc gctggtcgag gccggcgtgc ccgccgaccg catccgcacc
     8101 gagcgcttca ccacccacct gcccgccggc gcgcatccgg tcggggtctc gagcactgcc
     8161 gaggccgccg aggccgcgac caaggacatc accatggtcc tggtgctcga cggcaaggag
     8221 cacgagatcg cgatcggtcc cgacgagcac ctgctcgacg ccggcctcaa cgccggcctc
     8281 gacctgccct tctcgtgcaa ggccggcgtg tgctgcacct gccgcgccaa ggtcaccgag
     8341 ggcgaggtcg tgatggacaa gaacttcacc ctcgaggcgg acgaggtcgc gcagggctac
     8401 gtgctgagct gccaggcgcg cgccaccacc aagcgcctga agatcagctt cgacgagcgc
     8461 tgacacggcc tgcggaccga cgaagtccgc acgcccgcga caccttcgga cggccgtctc
     8521 gacggccgtt ttcattggcg gacggcaacg cgccccccct cccctgatgc aggtccttgc
     8581 cgaatcggtg gcggcctgct atcccttcag acttcatcca cactttccag cgcgcagacc
     8641 atggccggct cccacgctct cggcaccgcc ttcgaaccgt cctcgatcgc cgtcatcggc
     8701 gcatccgacg cccccggctc ggtgggccgg gtcatcttcc gcaacctcgt cgagggtggc
     8761 tatcgcggcg cgctgtacgc ggtcaatccg aagtacgaca gcatccagga ccacccctgc
     8821 caccgctcgg tcgaggacat cggccggccg gtcgatctcg ccatcatcgc cacccccgcg
     8881 cgcatgctgc acaccgtcac cgcgcagtgc gggcgcagcg gcgtgcgcaa cgcggtcatc
     8941 gtcagcgcca gcggcaacgc cctcgagcgc cgcatcatcg agaccgcgcg cgagagccgg
     9001 ctgcgcctga tcggcccggg cagcctgggc atcgcccgcc cgggcagcgg gatcaacgcc
     9061 gcgctcaccc gcatcgcggt caagcccggc gagatcgccc tggtctcgca gtcgggcgcg
     9121 atgtgctcgg tcgtgctcga ctgggcactg accaacgacg tcggcttctc gtcggtgatc
     9181 tcgctcggcg gcacggtgga catcgactac ggcgagacgc tggagtacct gatccacgac
     9241 gcgcagacgc gctacatcct gctgtacgtg gatcacgtcc gcaacgcgcg ccgcttcatg
     9301 agcgcgctgc gctcggcctc gcgcgtcaag ccgatcatcc tgctcaaggc cggccgccac
     9361 ggacgcggcg acaacaacgc ccccgaggtc gacaacgccg ggctcgccga cgtggtcttc
     9421 gacgccgcga tgcgacgcgc gggcgtggtg cgcgtgcaga acatcgacca gctcttcttc
     9481 gcagccaagg ccttgtcctg cggctttcgg ccgcgcgagg acagcctcgc catcgtctcc
     9541 aacggcagcg gcccggccga cctcgccgcc gaccgcgcca aggacctcgg cacggagctc
     9601 gtcagcctgg gctcggcgac ggtggccacg ctcgagcgcc tcggcggccg cgagcggcgc
     9661 tcgcacaacc cgctcgacct cggcggcgac gccagcgcga agctctatcg cgacgccatc
     9721 ctcgccctcg ccgaggacgc cgcggtgtcc aacctgctgg tgatcctgtc gccgcacgcg
     9781 ctcgtcgatc cggtcgaggt ggcgcaggac atcatcgacc tcgccgccca ggtgcggctc
     9841 aagctgtgct gctgctggat gggcggcggc caggtcgcgg aggcgcgcac gctgctcgcc
     9901 caggccgggc tgccggtgtt cagctcgccc gaggcggcga tcgagctgtt ccacaacatc
     9961 tcgcgcttcc accacagcca gaccctgctg ctgcagaccg ccggcggcag cgccaccgcg
    10021 tatcgccgca cgggtggcgc gcgcgtgctg atcgagaccc tgctcaacca gcgccgccac
    10081 gtcctgtcgg caatggagtc caaggcgctg ctgcgcagct tcggcatccc ggtcacgcac
    10141 accaccgtcg cccgcgacgc caccgaggcc ttgttcgtcg ccgagcagac cggctttccg
    10201 gtggccctga aggtcgacgc gccggagctc gcgagcaagt ccgaatccgg cggcgtgcgg
    10261 ctcaatctca acaccaccga ggcggtgtgg agcgcctacc acgacatcat cgagacggta
    10321 cgccagcgcc gccccgaggc ccgcatcaac ggcgtgtcga tcgagcccta cctgtatcgc
    10381 ccgcagtcac gtgcgttcag catccaggtg catcgcgacg cgatcttcgg cccggtgatc
    10441 agcctcggcg cgcaggacgc ctccgccccg cgcaccttcg cgctgccgcc gctgaacgcg
    10501 gtactggcgc gcgacctcat cgactcggcg acgccggtcg ccgcgcaggg gccgcgcagc
    10561 cgggcgggcg cgctcaaccg cgcggcgatc gagcaggtgc tggtgtcggt ttccgacctc
    10621 gtgtgcgagt tgccgtgggt gcgcgagctc gcgatcgacc ccctcctcat cgatggcgac
    10681 ggcgccatcg cggccgatgc ccgcgtggtc atcgaccagg gcctccccgc gggcagcgac
    10741 cgctacgccc acatggcgat ccatccctat ccgctgcacc tgatccagga ctggaaggtc
    10801 ggcgacggca ggccggtgcg cacgcgcccg gtgcgccccg aggacgccaa gctgctgctc
    10861 ggcttcttcg acgcgctgag ccccgagacg cgcttcatgc gcttcatgga ggagctggac
    10921 gagctcagcc cggcaatggt ggcgcgcttc acccagatcg attacgactg cgagatggcc
    10981 ttgatcgcca ccaccatcgc ggacaaggac gccgagcgga tgatcggcat cgcccgctac
    11041 gcgctcgccg ccgacggcga gtcggtcgag ttcgccctcg tcgtctccga cgactggcag
    11101 cgccatggcc tcggccgccg cctcatgggc gcgctcatcg aggtcgcccg caacaagggc
    11161 taccgcaaca tcttcggcga cgtgctgggc aacaacgcca agatgctgcg cctgatgcac
    11221 agcctgggct tcatggtgca gccacacccg gaggagagca gcctgcgccg cgtggtgaag
    11281 gtgctgcacg gcaactagca cgaccgccgc ggcgccagcg tacgctcaga aatcgcccca
    11341 gcgcgcctgc agcgcagcca ccgcggcgag gcccgccgtc tcggtgcgca gcacgcgcgg
    11401 cccgaggcgc acggggcggc agccggcagc gtcgaaggca gcgatttcga cctcgctcca
    11461 gccaccctcc gggccgacca gcaggtgcac cacgtccttc ggctcgggct cgtccgcaaa
    11521 gcccgcggcc ccgcccggcg cgagcacgta gttgagcgca tcgcgatgcg ctcccagcca
    11581 gggtgccaac gcctgcaggg gacggatctc gggcacccgg ttgcgcccgc actgctcgca
    11641 ggctgccacc gcgacctgct gccaatgcgc cacgcgcttg tcggcacgct cgccggccag
    11701 gcgcagcacc gagcgctccg cctgcaccgg ctgcaccgcg tgcgcgccga gctccaccgc
    11761 cttctgcacc acccagtcca tcttgtcgcc cgacgccagc gcctgtacca gcacgatgcg
    11821 cagcggcgac tcgcgctcga ccgcgcgcgc ctcgccgagc tgcgcgaaca ccgccttgcc
    11881 gcgcactgcg aggcgcgcct cgacctcgcc gccgctgccg tcgaacagca ccaccgcctc
    11941 gccgtcacgc aggcgcagca cgcgcagtgc atggtgggcg agcgcatcgg ggagcgcgac
    12001 ctcgccgccc gcgggcaggc gatccggaaa gtggaatcgt gaaatcatcg taagattata
    12061 ggccctgccc tccctccgcc cgccggcaag gagcccgtca tgcccaccgc cgcccaccgc
    12121 ctcgcccgtg cccgcgccct cgaatcgatg gtgcgcgaca tcgcacgcgc cgagatcctc
    12181 ccgcgctatc tcaagtccgc gcgcaaccgc aaggccgacg gctcgctgtt caccgaggcc
    12241 gacatggcct cgcagcagcg cttcagcgag gccctgcccg ccttcctgcc cggcgccgtg
    12301 ctcggcgagg agatgaccgc ggccgagcag gcggcgctgt ggaaggaagg cgcgcgcggc
    12361 ctgtggtgca tcgacccgat cgacggcacc accaacttcg ccaacggcat ccccctgttc
    12421 gcggtgtcga tcgcctacct gatcgaccac gagccggtga tcggcgtggt gtacaacccg
    12481 atcaccgacg aatccttcta cgccgcccgc ggcgccggcg ccttcctcaa cggcaccgag
    12541 ctgccgctgc gcgcgggcgc gaccgagctg cgcgacgccg tcgccggcgt cgatttcaag
    12601 cgcatcagcc accacctcgg cgacgagctc gcggtgcgcc cgccctacta ctcgcagcgc
    12661 aacttcggct ccagcgccct cgaatggtgc ttcgtcgccg ccggccgcct cgacgtctac
    12721 ctgcacggcg ggcagatgct gtgggactac gccgccggcc gcctgatcct cgccgaggcc
    12781 ggcggtgtcg ccgaggcgct cgacggcggc gtgctgatgt ccggcccagc gatcaagcgc
    12841 ggcgtcatcg ctgccaccag cccggcgctg ttcaccgagt ggtcggcctg ggtcaaggcg
    12901 cgctcctgag ggctcgcgca ccgctttatt gcggtgcaaa atccgtgtcg acaccgactc
    12961 gccagcggcg gaacccacca tgtccatgaa gcacccgatc atcgccgtca ccggctcgtc
    13021 cggcgccggc accaccacgg tcaagcacac cttcgaggcc atcttccacc gcgagaacgt
    13081 caacgccgcg atcgtcgagg gcgacagttt ccaccgctac acccgcgcgg agatgaagca
    13141 gctgatcgag gaggccgagc gcgagggccg gcgcggcatc agccacttcg gcccggaggc
    13201 caacctgctc tccgagctcg aaagcctctt ccgcgcctac ggcgacgccg ccaccggccg
    13261 ccgccgctac tacatccaca acgaggccga ggcgatgcgc tggaacctgc cgctcggcac
    13321 cttcaccgag tgggaagacc tcccggtcgg caccgactgc ctcttctacg agggcctgca
    13381 cggcgcgctg gtcaccgacg cggtggacat cgccggccat gtcgacctgc tgatcggcgt
    13441 cgtccccacc atcaacctcg agtggatcca gaaactgcac cgcgacacca agatgcgcgg
    13501 ctacaccgcc gaggccgtgc aggacaccat cctgcgccgc atgcacgact atgtgcacta
    13561 catcgtcccg cagttcgccc gcacccacat caacttccag cgcgtgccgg tggtcgacac
    13621 ctccaacccc ttcatcgcgc gcgacgtccc cacccaggac gagtccatgg tggtgatccg
    13681 cttcaaggac ccacgcggcg tcgacttccc ctacctgctg cgcatgattc acgacgcctt
    13741 catgagccgc gccaacacca tcgtgatccc cggcggcaag ctcgacctcg caatgcagct
    13801 gatcctcacc ccgctgatct ggaagctgat ggaacgccgc cgccagtggg tttgaggcgc
    13861 gaccgaacgc cgccgacgga actccccggc agcccccctc cccccgcgcg cggtcgcggg
    13921 gccggggcgg tgcgcgccgc ctacactcgc ggcccttcgc tgcgctcagg gctgccctcg
    13981 gcggaggacg ccgcgggggc ggcgacgcaa actcgtcgct gcgctcctca aacatgcgtc
    14041 gccttgtttc ccccgcgacg ccctccacct cggcgctcct gaagttggcg cgcaccgccc
    14101 cggccccgcg accgaatcga cgaagctgcc accttctcgc ctccacctcc cgcaatattc
    14161 ccgcaatgca acattggcat ccccggggtc ttttaaggga taattccgat ctttcccgat
    14221 ggcggcctcc ggcccgaaaa cagcatgcag tcgacccgca acgtccagcc cccggtcttc
    14281 aaccccatca ccggcgccat ccgcgccctc gcgatggacg cggtgcagca ggccaactcc
    14341 ggccacccgg gcgcacccat gggcatggcc gagatcgccg aagtcctctg gcgccaccac
    14401 ctcaagcaca acccggccaa ccccaggtgg gccgaccgcg accgcttcgt gctgtcgaac
    14461 ggccacggct ccatgctgat ctacgcgctc ctccacctca ccggctacga cctgccgatc
    14521 gaggagctca agcgcttccg ccagctccac agcaagaccc ccggccaccc cgaatacggc
    14581 tacgcccccg gcatcgagac caccaccggc ccgctcggcc agggcatcac caacgccgtc
    14641 ggcatggcgc tggccgagaa gatcctcgcc gccgagttca accgtcccgg ccacgacatc
    14701 gtcaaccaca acacctatgt cttcctcggc gacggctgcc tgatggaagg catctcgcac
    14761 gaagcctgct cgctcgccgg cacctggggc ctgggcaagc tggtcgcctt ctacgacgac
    14821 aacaacatct cgatcgacgg ccatgtgcag ggctggttca ccgacgacac gccgaaaagg
    14881 ttcgaagcct acggctggca ggtgatccgc gacgtgcagg gtcacgaccc ggtcgccatc
    14941 gaagccgcca tccagcaggc caaggccaac accgcccagc ccacgctgat ctgctgcaag
    15001 accatcatcg gcgccggcgc gcccaacaag caggacagcc acgacgtgca cggcgccccg
    15061 ctcggcgccg ccgagatcga ggccgcgcgc gcccatatcg gctggaacca cccgcccttc
    15121 cacgttccgg ccgacatcta cgccgcctgg gatgcccgca ccaagggtgc ctcgctcgag
    15181 gcgcagtgga acgccgcgtt cgccgcctac cgtgccgccc accccgagct cgccgccgag
    15241 ttcgagcgcc gcatggccgg caatctgccc gccgactggg atgcccacgt cgccgctgtg
    15301 ctcgccaagg tcaccgacaa ggccgagacc atcgccaccc gcaaagccag ccagaacgcc
    15361 atcgaggcct acgcgcccaa gctgcccgaa ctgctcggcg gctcggccga cctcgccggc
    15421 tccaacctga cgctgtggtc gggcgccaag ggcgtcggca agaccagcgg cggcaactat
    15481 gtctactacg gcgtgcgcga gttcggcatg gccgcgatcg ccaacggtgt cgcgctgcac
    15541 ggcggcctca tcccctacac cgccaccttc ctgatgttca gcgagtacgc gcgcaacgcc
    15601 ctgcgcatgg ccgcgctgat gaaggtccgc cagatcttcg tgttcaccca cgactcgatc
    15661 ggcctcggcg aggacggccc cacccaccag ccggtggaac agaccgcgac gctgcgcctg
    15721 atccccaaca tggacgtgtg gcgcccctgc gacaccaccg aatccgcggt ggcatgggcg
    15781 aacgcgatcg agcgcaagga tggccccacc tcgatgtgct tctcgcgcca gaacctgccc
    15841 ttccaggcgc gcagcgccga gcaggtcgcg gccatccgca agggcggcta cgtgctgtcc
    15901 gaggctgcgg gtggcaagcc gcaggcggtg atcctcgcca ccggctccga ggtcgcgctc
    15961 gccatggccg cgcagaagac gctggccgac caaggcgtcg cggtgcgcgt ggtgtccatg
    16021 ccctcgacca acgtcttcga ccgccaggac gccgcataca aggcgagcgt gctgcccgcc
    16081 ggcctgccgc gcgtcgcggt cgaggccggc acgaccgacg gctggtacaa gtacgtcggc
    16141 ctcgagggcc gcgtgatcgg catcgaccgt ttcggcgagt cggccccggc gggcgagctc
    16201 ttcaagtatt tcggcatcac cgcggatgcg gtggtgcagg cagtgaagtc ggtgctctga
    16261 cgagaccctg gcgcgggagc ggctccggaa gcggaccgct cccgctgcac ttcaggacac
    16321 ggtcccgcgc ggaccggcag ggcagcagca aacacaaatc acccggtttt tcaccgttat
    16381 ctcagggaga agcaacgatg agcatcaagg tcgccatcaa cggtttcggt cgtatcggtc
    16441 gctgcacgct gcgcgccatc tacgagcagg gcctgcagaa cgaattcgaa gtggtcgcca
    16501 tcaacgcctc cggcgatctg gccaccaacg cccacctgct caagtacgac accacccacg
    16561 gccgcttcgc cacctcggtc gagaccgagg gcgaggactg catcatcatc gacggcaaga
    16621 agatcccctt ctactccacc aaggatccga agggcgttaa ctggggcagc cacggcgtgg
    16681 acgtgctgct cgaatgcacc ggcgcctaca ccaccaaggc caaggcccag gccctgctcg
    16741 accagggtgc ccgccgcgtg ctgatctccg ccccgggcgg cgacgacgtc gacaccacca
    16801 tcgtcatggg cgtcaatgag gaagtgctgc gcggcgacat gaccgtcgtc tccaacgcct
    16861 cgtgcaccac caactgcctg gccccggtcg ccaagatcct ggccgacagc gtcggcatca
    16921 agcagggcct gatgaccacc atccacgcct acaccaacga ccaggtcacc gtggacgtgc
    16981 gccacaagga cctgcgccgc gcccgcgccg ccgccgccaa catcatcccg accaagaccg
    17041 gcgccgccaa ggccgtcggc ctggtgctgc cgcaactggt cggcaaggtc gatggcttcg
    17101 ccctgcgcgt gcccacgatc aacgtctcgc tggtcgacct taccttcacc gccgagcgcg
    17161 ccaccaccaa ggaagagatc aacgcgctga tgaccgccgc ggccaacggc ccgctcaagg
    17221 gcatcctcgc ggtcaacacc gaaccgctgg tgtcctccga cttcaaccac accaccgtgt
    17281 cctccacctt cgacgccacc cagacccgcg tcatcaaggg cgaggacggc tcggtgctgg
    17341 tcaaggtgct ggcctggtac gacaacgagt ggggctactc ctgccgcatg ctcgacgccg
    17401 cgcgcgcctt ctgcaacgcc aagtaagccc gaccccagtc gaaccgacgc cctgccctgc
    17461 agggcgtttt tccaggatcg aacgaatcat gcaagtcaag aaactcaccg acctcgacgt
    17521 gcgcggcaag aaggtcttca tccgcgccga cctcaacgtg ccgcaggacg acgccggcaa
    17581 catcaccgag gacacccgca tccgcgcctc gctgccgtcg atccagtact gcctggacaa
    17641 cggcgccgcg gtgatggtca cctcccacct cggccgcccc accgaaggca cggtcggccc
    17701 cgacgacacc ctggccccgg tggcggtacg cctcggccag ctgctgcacc gcccggtgcg
    17761 cctggtggcc gactgggtcg agggcggctt cgagctcaag ccgggcgagg tcgtcctgct
    17821 cgagaactgc cgctgcaaca agggcgagaa gaaggacaac gaagagctgg cgaagaagat
    17881 ggccgcgctg tgcgacgtct acgtcaatga cgccttcggc accgcccacc gtgccgaggc
    17941 caccacccac ggcatcgccc gcttcgcccc ggtggcctgc gccggcatcc tgatgggcgc
    18001 cgagatcgac gcgctcggca aggccctgca gtcgccgcag cgcccgctag tggcgatcgt
    18061 cggcggctcc aaggtgtcgt ccaagctcac catcctgaag tcgctcgccg acaaggtcga
    18121 ccagctcatc gtcggcggcg gcatcgccaa caccttcctg ctcgcctccg gcaagcgcat
    18181 cggcgagtcg ctcgccgagc ccgagctggt caaggaggcg caggcgatca tggacatgat
    18241 gaaggcgcgc ggcgccgagg tgccgctgcc ggtcgacgtc gtcgtcgccg acgaggtctc
    18301 cgcgctggcg cgcgccaacc gcattccggt cgaagaggtc ggcgcgcacg accgcatcct
    18361 cgatgtcggc ccgaagaccg ccgccaagct ctcggagatc atcgccaacg ccggcaccat
    18421 cgtgtggaac ggcccggtgg gcgtgttcga gctgccccag ttcgccggcg gcaccaagat
    18481 gatggcctcg gccatcgcgc actccgaggc cttctcgatc gccggcggcg gcgacaccct
    18541 ggcggccatc gcgaagttcc acatcgccga ggacgtgggc tacatctcca ccggcggcgg
    18601 cgccttcctc gagttcctcg agggcaagac cctgccggcg atcgctgcgc tggaagcgcg
    18661 cttcaaggac tgaggcgcac aggcagtcga gccgccgcgg gcgcgggctg ggtcgccgcg
    18721 ttcgcgccnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnntg ctgcgttcgc
    18841 gcctgccggc gctcctacaa gggcgtggtg cgggctggat tgccgcgttc gctggcgctc
    18901 gtgcagggcc tcggtgggtg gtggtttatg taggagcgcc ggcaggcgcg aatgtggcct
    18961 tggagcttgc gacgcgagcc gcaatggcgg ccgcggttca gccccgccgc agccagcgca
    19021 ccccctgccc cgccatcttg cggcgcagcc aggcgagctg ggtctgcagg ggcagctcct
    19081 tgggacagag gtcgttgcag gccagcaggc tcatgcagcc gaagatgcct tcgtcgttgc
    19141 cgacgagctc gtagaaatcg gcatcgtcgc gcgtatccgc cgggtcgagg cggaaacgcg
    19201 cgatcttgtt gaggccgacc gcaccgacga agccctcgcg catctgcgcg gtcgcgcacg
    19261 cggcgatgca gcagccgcac tcgatgcagc gatcgagctc atagacctcc tcggcgagcg
    19321 ccggctccat gcgcgcctcc aggcggtcga ggtcgggctc ggcgtcgaga tgcacccagg
    19381 tctgcaggcg ctcggcgagc tcgcgcatcc agctcccgac atccaccgac aggtcggcca
    19441 ccaggcggaa caccggcagc gggtagaggc tgaacgccgc cggcagcgtg ctcgtcagcg
    19501 tgcggcaggc cagcccgggg cgaccgtcga tcaccatcgc gcacgcgccg cacacccccg
    19561 cacggcagac gaagtcgaag ttgaggtcgg gcgcctgggt gtcgcggatc gcgttgagcg
    19621 cgatgaacag cgtcatcccc ggctgctcgt cgagctcgta gtcgaccagg cgcggcgcgc
    19681 tctgcgggtc gcgcgggttg tggcggaaga tcgagatctt caggcggcgg ctcatcgcgg
    19741 cgctccttct tcgatgtcgg cgaggcgttc gttgtcgccg cgatagcgct cgggcaggcg
    19801 catgcggaaa tccagcagtg cggcctgcag cggggtgcgc ccggcgcctt cgaggcgggc
    19861 acggatcgat tcgatctcgg cctcgcgcag cgcggtggcc gggtgctcga cgatgttgcg
    19921 cgtgccatag ccgcggaagc cgggcggcag ctccatgtgc tccaccgtga tcggctcgta
    19981 ctccagcacc ggcgcggacg cccccgtcgg ccaccacgcc agcgtgcggc gcagccagtc
    20041 acggtcgttg cgcgccgggt agtcctcgcg cgcgtgcgcg ccgcggctct cgcggcgctc
    20101 gagcgcgccc tgcgcggcac acagcgcgag cgcgagcatg cgcggcagcc ggtaggcggc
    20161 gaccagctcc gggttggcgt cgagatggct gctcgcgatg ccgacccgca gcgcgcgcgc
    20221 gtgcaggtcg gccagcctgg cgaccgcgct gcgcagcccc gcctcgttgc ggaacaggcc
    20281 gacgtgctcg gtcatcgtcg cctccatctc gcgccgcagc gaggtcgcgc tgtcaccgcc
    20341 cgccgcgggc gccggacgcg ccgcgattgc ctccagggcg gcgcgctcgc ggccgacgaa
    20401 ctcgcgcgca agcccgggcg agaactgcaa tgcgccggcg tgcgactcga caaagtcggc
    20461 gacgtactcg cccaccagca tgcccgccac caccgtctcg gcaagcgagt tgccgcccag
    20521 gcggttgaag ccgtgcaggt cccagcacgc cgcctcgccc accgcaaaca ggccgcgcag
    20581 cgagggcgac tcgccgcggt ggtcggtgcg gatgccgccc atcgaatagt gctgggtcgg
    20641 ccgcaccggg atccagtcgc gcgccgggtc gatgccgagg aagtggcgac agatgtcctt
    20701 cacctcgcgc agcttgtggt cgatgtgcgc agcgccgagc accgcgatgt ccagccacag
    20761 atgctcgccg gcggccgact tgacgccctt gccgcggcgc atgtgctcgg ccatgcggcg
    20821 cgagaccacg tcgcgcgagg ccagctccgc cttctccggc tcgtaatcgg gcatgaagcg
    20881 gtggccgtcg acgtcgcgca gcaggccgcc gtcgccacgg cagccctcgg tgacgaggat
    20941 gccggcgggc acgatcgcgg tggggtggaa ctgcaccgcc tccatgttgg ccaggcgcgc
    21001 caccccggtc tcgagcgcga tcgccgcgcc catgccctcg ttgatcaacg cgttggtcga
    21061 gataccccag atgcggccga agccgccggt ggcgatcacc gtggccgcgg ccaggatggc
    21121 gtacagctcg cccgtctcca ggtcgcgcac caccgcgccc tggcagcgtc cgccgtcgtg
    21181 gatcagcgcc accgcctcgc tgcggttgcg caccgggatg ccctcggcca ccgcgcggtc
    21241 gccgagcgcg tagagcatgg tgtggccggt gccgtcggcg gtgtagcagg tgcgccactt
    21301 gcgcgtgccg ccgaagtcgc gcgcggtgat gaggccgtgg gcctcgtcgc gctcggtcag
    21361 cgtgacgcgc tcgccgttga tgaccgcctc gtgcgcgccg cgctgcacgc ggttccaggg
    21421 cacgccccag gccgcgagct cgcgcaccgc cttgggcgcc atgtgggcga acatgcgcgc
    21481 gacgagttgg tcgcagcccc agtccgagcc gcgcacggtg tcgccgaagt gcacgtcctc
    21541 gttgtcgccc atgcccttga aggcgttgcc caggctggcc tgcatgccgc cctgcgccgc
    21601 caccgagtgc gagcgcttgg ccggcaccag cgacagcacc tcgacgcgca acccgcgccg
    21661 ggccgcgccc accgcggtgc gcaggccggc gaggccgccg cccgcgacca gcacgtcggt
    21721 gtattcgatc ctcatcgcgc ctcctcggcc gcagtcgttc cgcgctgcca ggtcggcacg
    21781 tagcgctcgc cggcgcgcgg cgcatgctcg atgcccatgc ggatctccgc cagcagcgtg
    21841 gtcagcccca gggtgagcag gaaggcgatc agcccccaca tcgcccactt cagccggcgc
    21901 cggctggcgc gcgcgtcgcg gccctcgaac cagccccact tcaccgccag gcggtacagg
    21961 cccacgctgc catgcacctc gaccgcgaac agcagcgcca ggtacagcgg ccagaagccg
    22021 ccggtccaca cgcggtcggc ggattcgaac ggcccgatca ggtcgggatg cgtgaacatg
    22081 gcgtacagat gcaccggcgc gaggaagaac atcgcaaagc cggtggccac ctgcacgaac
    22141 cacagcgtgg tgtcgccatg gcgcaggcgg ctgccgtggc gcgcggcgat gcggtactgg
    22201 cgccagtcgg caggaaactt gcgcagcgcc agcaaggcat gcagcgcgaa cagcgcggcg
    22261 atcgcggcga cgaaggccaa caccagccag gcctgcgggc gcggcaggaa gaagtagccc
    22321 tcgaagaagc gcgccacgct ccaggcgaag tccgcgctga tcaggatcgc ggagacgaag
    22381 cccatgtgca gccacatgaa gagggcgagg gcgaggccgg agagtgcctg gagcaggtcc
    22441 aggcgcgccg gccagagcga cgcggccgaa gccgcgcgag atcgcgggag cgtcatgagg
    22501 atgcggtttg cgggacaggc agcacactat acaacgaatg ccgcagtgca caacgcgcag
    22561 cgcctggcca cacacccttc gcagcctcga ccagtggatt aagtcacact cctcgttgcc
    22621 gcaacgcaac agcgtaaagc gcgaagacct ctccggaaag gcagaggcct cccccggcgc
    22681 tcacaccaag ctcgccgtcc gcgggcgacg aaagatgccg aggaaaaaca ccccgaccac
    22741 gagcagcgcg ggcagggaag gctcgggaac aaaggcggcg cgcacctggc ggtacatcgc
    22801 gtcggcaagg atcacatggg cagccgcgga cggatgcacc acgtcccaga acaggtgctc
    22861 atcggggttc gcacagatcg tcggcgccgg cgcaccgggt gtcggtgcga ggtacaaacc
    22921 ctgcaggcag gcggtttcga tgtcgctgaa gccattcgct gcaggactcc gcaccacctc
    22981 gtcgagcagg ccgaaggcgt cgaagcgcag cacctcgagc tcggggaccc cggcgaagga
    23041 ccgcaaggcc tggtcgatcg cctggttgaa cgcgatgctg tactggcgcg cagcttcctg
    23101 cgcctgcgcg ccgaaggccg ccaccaccgg catcgcgccg atgtccggca cggtgggcac
    23161 catgaactgg cgcgcgccca gcccgaccag cccgccgatc acgccggcca cgtcccccgc
    23221 cgcctcgacc aggcgggcgc cggcggcgtc gggaccgctc acctgggcga ggcgcagcac
    23281 gtcctgcagg tcgttcgcgc ccgcccacac cagatacagc gccgaggcgt cggcagcgcc
    23341 cccggcgagc ccgtcgcggt agcgcccgaa ctgtccggtg agactgaagg acgcgaagtt
    23401 ggccggccac gcgaggggcg gcaggccgtt ggcgtcgacg tcgaaggagt ggtagcgcga
    23461 ccgcgccccg cccacggcaa agttcgtacc gcccggcagc gccgccgggg cgagctcccc
    23521 gggaaggctc aactggtccc acaggcgctc ggcatacacc ggaccattgg tgaaggtccc
    23581 ctgggcatag gggggcgaca ccgggatcgc gaggccgccg gtcacgggat tggcctgacc
    23641 ggtccacgca tacaggttgc ccgtatcgga caggctgtcg ccgaatacgt acaggctcga
    23701 cggcagcgcg tgggcgcttg ccgacagcat gcacaaggcg acgctcgaca ccgccatcgc
    23761 cgctgcgcga cggctcgctt tgacgggtgg ggccatggtg ctcctccagt gtagggtgag
    23821 gctggtgccg ccagccgggt gccatccgca gacaagcttt attcaatata tgccacggcg
    23881 gccgctccgc aagaagcacg cgccgcgcgc gaggtcgccg atgcggccgc gctgctagaa
    23941 tgccggcacg ccaccgaccg gagcagcccg gatgtcccgc cacaccaaga tcgtcgccac
    24001 cctcggcccc gcctcgtccg acctcctcac cctcgagcgc atggtgcacg ccggcctcga
    24061 cgtggtgcgg atgaacttct cccacggcaa gcccgaggac cacgtcgctc gcgccgagac
    24121 catccgcgac gcctccgcgc gcgccggccg cccgatcggc atcctcgccg acctgcaggg
    24181 ccccaagatc cgcgtcggca agttcgagga ag
//
LOCUS       DAOTIN010000044        24067 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_2453_length_24067_cov_8.597909, whole genome shotgun sequence.
ACCESSION   DAOTIN010000044 DAOTIN010000000
VERSION     DAOTIN010000044.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 24067)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 24067)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24067
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2453_length_24067_cov_8.597909"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..5219)
                     /locus_tag="P5537_08530"
     CDS             complement(<1..5219)
                     /locus_tag="P5537_08530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat-associated core domain-containing
                     protein"
                     /protein_id="HRV78127.1"
                     /translation="MLAGTALLAALFLSVRPGLAAGTASSQSGVALGGIQQSGCGITM
                     NCAPDTTQGVPAAPEPPAAGQCVANNAGNPCGNASGPASQGSATGQDLGAGNPIDVLS
                     GNKYQQEVDLPALPGVLGLEIVRHYNSWRARLGDAGALGSGWRLSYETRLDIRDDRLE
                     ILQADGTRVIFARRPGEPQRCASRDPSRGEIRIRPRTSGDEYLWRWPDGRSLLFDHAG
                     RLVQILLPSGEFVSLRHDQAGRLVQVTDPQGRSLQLHYPPRGNGSDGIAHIDSPLGRF
                     SFTQESVAIPTRTHAGATAGPGPLHGRQMTSSDRSPASKRGAPAKSRTARKTAATRLV
                     RVDYPGPQASTGGGAAARAYHYEDPRHPVALTGISVLARQPDGPPAPQRIASYAYDAA
                     GRGIRSVRGALPAEGETGPEDVRLEYPARGRTELTNSLGQRTTYLGAVIAGQRRLLEV
                     RGPGCARCGPTNVRYGYTPDGRLRVLTTLDAEGRPRTSTQHRFDAYGRIVETLSADLT
                     GARPRLLDRARHEHADASAIADAPSEGAAHELEPGATPPPRAVIRASVIPGREHRIEL
                     RYNAAGQPVELREAGFSPIDTEGRPNPVPIERRLHWRYATINGRSVLVELDGPLPDGP
                     DASPHDSDRVRLHWDERGSFIRAVEGPGGRRSEIDSDPVTGLPLRVRDAEGHEIRLRH
                     DAAGQPIEWSSGSPGEALEHRHAAAYDAFGNLVELRTGEDEDHLRPRWRRAYDAAGRL
                     QWHADALGALKTWTYDHESRVVEAALRSTSRLLRRRWRYDERGRLADIGDDTGFTRSL
                     HYDDAGRLVGLLDSHGRELLPPIRPRRDQAIATTPPARPRIIHDDFGRAVLEHSADAG
                     TRWRSFDAAGRLVAMGDALGHRARYTWDLRGRILAQQITDGHSGTTETTRWRYDGPRL
                     MEVEHPNGRERYEYDPRGLRSARIVSLKRDDGELVVVTRYEHDAAGRLVASTLPDGSR
                     LRYERNGQGQVVALKRQPVATSWLHALAREQTIASAFERDLFGLRSFQAGNGVRTVHE
                     RTRAGTLVRVAHLRADARGTPLRNARALLPIEPGQPLAARIERIFGISAAHAAGTGAD
                     AHASTQEEAGPQPQENAAHAGPLLLDHEYRWDPEGNLLHERRHEPDGPLPSTRRSQAY
                     DLRNQLVASVEWRDDDGTLAETGVWRYAYDPHQRRVLAQEGAAAQQDLAGNTRPTRFS
                     AASHRALSSGPHQTNPAAAGLAADRAGEAFTAAEHDASGQPGRFGARSLRWDALGRLT
                     EVRDGERSIARYAYDHRGLRILRTRLDPATAAPTTTHIVHDDARQPLAELDADGRLVR
                     QYLWLADLPLAVLDIPAQPATETGSARRLLEDLRRIVQSWLDPQAGLAWLHTNHLGAP
                     ELATDPAGQPIWRARYAPFGAATLTPSPARPDFTLDLRLPGQVFDAETGLHYNRARYY
                     DPGEGQYLTPDPLGTPDGPNPYAYAAFNPLGRVDPDGLVLFAFDGTDNSSEVSELERL
                     GGSETNVVRFLDLYADGPGNYVSGVGTRHHENGRRNYLGEAYEDILPKGFGPIPDRGG
                     NYTGRERIERMWDYFVDEAEALDDNTVMNIDVMGFSRGAAQAREFANTLTELLVEHEG
                     RQLIRYPAIDPGTRREVTRCQPVKLRFMGLFDTVLSTDLPFAADYRLAIPDEFAYVAH
                     AVALNEYRSQPIGWDAGGYPFNAAFWDETRRNLDEKLHQGGFPLESIGASSRTQGQVR
                     IERGFIGAHADIGG"
     gene            complement(5348..6352)
                     /locus_tag="P5537_08535"
     CDS             complement(5348..6352)
                     /locus_tag="P5537_08535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TadE/TadG family type IV pilus assembly protein"
                     /protein_id="HRV78128.1"
                     /translation="MMRPPPPLPPQRRPLPGSRRRVLRGAGAAEFVIVAPALLALTLA
                     MLQTGLAYHARSIVNYASFEAARAGSVAHAGLASMRLAFARAMTSYYGGGRDLAEIAD
                     SFAAAQLDLATALRIEIVSPTRESFDDYHSPAAAQRLQTSARVLPSAQLGVLGCPADR
                     ANCNADPASNRSGQTLADANLLKLRVTWGLPPAKQVPLAGRFFTWALRTLDPDDDDTF
                     RRSLVEAGRIPMVSQVTLRMQSDAIENDAIRPRTRAGGDSQAPAATPLPGCTPTDPLC
                     TPDPATPDTPPQTPLSAGENGAPDDATASDGETGPEADTADPTEDAEDTDAAEEEPEC
                     "
     gene            complement(6349..6666)
                     /locus_tag="P5537_08540"
     CDS             complement(6349..6666)
                     /locus_tag="P5537_08540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004373405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF192 domain-containing protein"
                     /protein_id="HRV78129.1"
                     /translation="MRVLVARSFLQRTRGLLGRGPLAADEALLIDPCWSVHTFGMGFA
                     IDVVFIDARGTVLAVREALAPWRVAHCLGAAAVLEMAPGAARREGLAPGRSARRICAA
                     PHA"
     gene            complement(6669..7574)
                     /locus_tag="P5537_08545"
     CDS             complement(6669..7574)
                     /locus_tag="P5537_08545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HRV78130.1"
                     /translation="MNLAQMLALDERTAIAAVALLAGLGSAGIVTALARSVGAVQPED
                     RTWLDTPPRFLRLLWWPTRWIAHLIAPLLPGRLQAGLAVRLRLAGLDYTISPAQLLAH
                     RTVVALCGLAIGLGFAHAWGLPATIPALAGAAAGILIAWSWLDDRIRSRRRLMLKQLP
                     FVLDLVTLCVEAGLNLTGALQQAAAKGPAGPLREELHRVLRDVRAGKSRADALRGLAE
                     RVGEPAIANLVSTVIQAENMGMSLGPMLRAQGEQRRAERFARAEKAAMEAPVKMLLPL
                     IACIFPCTFIVLGFPIAVKFMTMGL"
     gene            complement(7571..8440)
                     /locus_tag="P5537_08550"
     CDS             complement(7571..8440)
                     /locus_tag="P5537_08550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HRV78131.1"
                     /translation="MNTLAASPAVLLATLAFGLASALLAWSAMRIAGNALARYRERFT
                     AEAHLQLEELFLFMDPARLFVLNLLAVTVGSVGTWLVSGEPLLALASAGALALLPRLA
                     FGLLRRRRLALIEQQLPDALQVIAGGLRAGVSMTVALQQLVREGRPPIAQEFDLTLRE
                     HRLGIPLDEALDHLAERVRLPSLTLVIAAMRIANETGGSLAEALERAALTVRSQLAME
                     GKIGALTAQGKLQAVVVGMLPLALLLVLDRMEPEAMAFLWHSPPGWATLAVIATLEVL
                     GVLLIRRIVAIDV"
     gene            complement(8437..9870)
                     /locus_tag="P5537_08555"
     CDS             complement(8437..9870)
                     /locus_tag="P5537_08555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpaF family protein"
                     /protein_id="HRV78132.1"
                     /translation="MFFRTPRRPPSTTAEPTPAPASPATDRRAGLVEAAPDASARAAI
                     EPRPSTLASNADFTWRKRIHERLLDTIDLRRRDLNRMSDGELRSETTALVREIIAAEA
                     TLPPALDREQLCREVLDEAIGLGPLEALLADEAVSEIMVNRYDQIFVERGGRIAPHPT
                     TFTSDRAVLGVIERIVAPLGRRIDESSPMVDARLRDGSRVNAIIPPLALKGPTLTIRK
                     FARRALEVEDLVRMGSLSHDMAGFLRICVEQRRNIVVSGGTGSGKTTFLNLLSNFIPD
                     GERIITIEDAAELRLRHSHLVSLEARPANLEGRGAISIRDLVRNALRMRPDRIVVGEC
                     RGGEALDMLQAMNTGHEGSMTTLHANSPRDALARLETLVLMAGMDLPLAAIREQIASA
                     VDVIVQQTRFACGARRVTSITELTGMEGGRIQLQELFRFERRGADSAADPGGGHFTGC
                     DAVPGFYEELRRQGVALDLHPFDRSRS"
     gene            complement(9883..11331)
                     /locus_tag="P5537_08560"
     CDS             complement(9883..11331)
                     /locus_tag="P5537_08560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein N-terminal
                     domain-containing protein"
                     /protein_id="HRV78133.1"
                     /translation="MTRTDPIHPVGLRGPLRSLLCATLLLGAPVLALPAPPVRPPASV
                     PIEAGRAALPVVHEIQMFAGETRVLPQRDAQRLAVGDAKVLSAAVLDEREILLIANGP
                     GDTMLQVWSRSGRSQRIKITVRQTDTARIARDLQGFLHDVPRLRTRTIGDNVVIEGEG
                     LSDAERDKVAELAKRFPQLIDFTSRVGLDRMFAFDVRFVEISRSGLRDLGIDWTTQGK
                     PLLGIGVIGDLYHDNRTGATVTRTLGTGEQRSEVSIEADRVSPFAANAALVGSFFGRL
                     NLLAQKGDAVILASPRLSARNRGEASFLAGGEIPVPVASATGTPSVTFKEYGVRLNIL
                     EPVADAAGTIRARIRTEVSSLDRSVAAQGVPGLLSRRTETEFNLRNGETLVLSGVLQR
                     EQQSDENAVPYLGEVPVLGHLFRSTRFNNRESELVVFVTPWLLEPGEGLLDPRAQLLE
                     HRAEQALAPPPEPAPVVREPADPAWNALYGGS"
     gene            complement(11318..12178)
                     /gene="cpaB"
                     /locus_tag="P5537_08565"
     CDS             complement(11318..12178)
                     /gene="cpaB"
                     /locus_tag="P5537_08565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly protein CpaB"
                     /protein_id="HRV78134.1"
                     /translation="MPKRVPRNLIILAVATLFGLGAAWLAARYLEERASEIELRQQGQ
                     MGRAVVAKTDLAVGTPLTHDLVAIREVPVEWLHSSAITPEQFERAAGAVLAQPARGGE
                     PLVWSQLEERRPASLSAHLAPGRRATTIPVDETSSLSGLLRPGDRIDLLATVQRDKQH
                     LTMPLLQGVRVLATGSRTRPGEDVGAGDPLGGTFGTLTLDLSEEEATRLVAARALARL
                     TAVLRNPQDIRTAPLLRTDALALLGLAPAPTAGGVPVIYGGVENPALIPTSSPLSRPA
                     PRAEPAHDPD"
     gene            complement(12186..12332)
                     /locus_tag="P5537_08570"
     CDS             complement(12186..12332)
                     /locus_tag="P5537_08570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78135.1"
                     /translation="MTEHLLILSIVLGVFALPAFDGKPLVLFFAEAVATGFARFLSSI
                     SLPI"
     gene            complement(12362..12970)
                     /locus_tag="P5537_08575"
     CDS             complement(12362..12970)
                     /locus_tag="P5537_08575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004356521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78136.1"
                     /translation="MAGARITPVIDDARVHGVPTRIRQFEAETSPAGVRAFYQKAVEG
                     KPLTARIDDWEILSWKQGTALRTLRLRPCRAALSPCTEGTLSESDLSLAAAPASPAPG
                     RPADSLLSTDLETNDGGRRARILVWHDESSPSWAAARLVRELSILGLALERRVPVTRP
                     GLEGLGLWFGARGREAVATVTRHGSGTTVTLQMIDHGVQDGR"
     gene            complement(13120..13890)
                     /locus_tag="P5537_08580"
     CDS             complement(13120..13890)
                     /locus_tag="P5537_08580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78137.1"
                     /translation="MKPRHLLLAIARPAESGQSTTEFLVLALVLVPLFMSLPLLGKYL
                     DLAHTTEQAARYVAFETAITGPARRTPTAEALAAQVRERIFSPSAAPILSRPADATAS
                     GRPANPLWTDHRGEHLLSDPASRVGVELGSHTDTAPASALLAGSLGLDLPAGTEYTGT
                     IRVSPRNVPGLAPFDTLGLTIHRHQVLLGHNWSAAGSAEYARRIEDAGPLAYPIQPLA
                     LIGNTVGRVLPPLVLDEAIEVGRVEAEILPCDRLEEGC"
     gene            complement(13887..15311)
                     /locus_tag="P5537_08585"
     CDS             complement(13887..15311)
                     /locus_tag="P5537_08585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004356517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein TadG-related protein"
                     /protein_id="HRV78138.1"
                     /translation="MVVFPRPGVGRHSPGAAPQRGQALVLGLFFVFATAAVLLLMFNG
                     GRTVDEKLRLTNAADATAWSVATLEARALNYDAYTNRAIVANEVAIAQAISLISWMHY
                     FETAVGSAPALNQVAMSWLYKPGEYPRLLQLLAGVNGSAYLDVGSGGSLRAIVEGLDT
                     ALGAIATAHDAVANALSLSQRVMHASLDTGIAQAGFANEFVHRIDPDMQASINPISHD
                     FRNLTRAMARDSAQGDARERIADVTLRSRDAFTRERVWSIRGLNLPPLQRKVELKRRG
                     GTELIGYDEWRALDTLEHQGQRMKRWRWRWRRTPLAWGGASFAGDEEADARRGHHGNT
                     YTSNPITTLRLAEPAIVDAGAARFSGLPETRELRDLSATADHRSGVTVHVAKARHRLR
                     GSGGIGSVQPQGNLRAFDATAPGGHLAAMARAEVFFERPAARSDHKTERASLYSPYWH
                     ARLTAVTPTDRAWAAGRQEGMALP"
     gene            complement(15350..15760)
                     /locus_tag="P5537_08590"
     CDS             complement(15350..15760)
                     /locus_tag="P5537_08590"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78139.1"
                     /translation="MEARCMPCSGLSRLPPPATLRKESYLHIDSTHPVCHYFFIIYRR
                     EAIMAAGSGLGQQRGQGMTEYIIIVALIAVGAIAVYQYFGQTVRNQTAAIATEIAGKD
                     GGTAKSAAQTAAGKAATEANTARTLDTYTGNAGR"
     gene            complement(15785..17449)
                     /gene="ettA"
                     /locus_tag="P5537_08595"
     CDS             complement(15785..17449)
                     /gene="ettA"
                     /locus_tag="P5537_08595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018610096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0045900 - negative regulation of
                     translational elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-dependent translational throttle protein
                     EttA"
                     /protein_id="HRV78140.1"
                     /translation="MAQYVMSMLRVSKIVPPKRQIIKDISLSFFPGAKIGLLGLNGSG
                     KSTVLRIMAGVDKEYDGEVQWLAGQRIGYLPQEPELDPAKTVKEEVESALGEIMEARQ
                     KLEEVYAAYAEPDADFDKLAEEQARYENILATAGNDVETQMEIAADALRLPPWDAVIG
                     KLSGGEKRRVALCKLLLSKPDMLLLDEPTNHLDAESVEWLEQFLTRFPGTVVAVTHDR
                     YFLDNAAEWILELDRGHGIPWKGNYSSWLEQKGDRLAQEAKQEAAHQKAMKTELEWAR
                     SNPKARQAKSKARLARYEEMASVEYQRRNETQEIFIPPGERLGDKVIEFHGVSKAFGD
                     KLLMDNVSFAIPPGAIVGIIGPNGAGKSTLFKMIEGRDKPDSGTVEIGATVKIAAVDQ
                     TREGLANDKTVFDAIADGADVLTVGRFEMPSRAYIGRFNFKGGDQQKIVGNLSGGERG
                     RLHLAKTLIQGGNVLLLDEPSNDLDVETLRALEDALLEFAGCALVISHDRWFLDRICT
                     HILAAEGDSQWFFFEGNYQEYEEDKKKRLGEEGAKPRRIRYKPIAR"
     gene            17601..17837
                     /locus_tag="P5537_08600"
     CDS             17601..17837
                     /locus_tag="P5537_08600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0001558 - regulation of cell growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PrlF family
                     antitoxin"
                     /protein_id="HRV78141.1"
                     /translation="MHTTLTSKGQVTIPKHIRDALHLEPGCAIEFRINREGEVVLTRP
                     GELRDEADRFERLRGKADVKWRTDDLMALLRGDD"
     gene            17837..18235
                     /locus_tag="P5537_08605"
     CDS             17837..18235
                     /locus_tag="P5537_08605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family
                     toxin"
                     /protein_id="HRV78142.1"
                     /translation="MLLVDTNVLIDVLEDDPRWADWSIDMLRRQSQVHRLAINPIIYA
                     ELSLTFSTVEALEEAVTDFGVEVVEIPRPALFLAGKAFVAYRRNGGQRTNVLADFFIG
                     AHAAVEGWPILTRDPRKYRQYFSSVELVAP"
     gene            complement(18364..18645)
                     /locus_tag="P5537_08610"
     CDS             complement(18364..18645)
                     /locus_tag="P5537_08610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HRV78143.1"
                     /translation="MTCELGFVDEALAEWRKLDGSIREQFKNKLAERLDALRVPAARL
                     SGHPDRYKIKLRSVGYRLFHEVRDEELIVVVVAVGKRERSAVYRAAARR"
     gene            complement(18635..18883)
                     /locus_tag="P5537_08615"
     CDS             complement(18635..18883)
                     /locus_tag="P5537_08615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000121741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HRV78144.1"
                     /translation="MAHQILVETTASVSELKKNPMGTVAAGEGFPVAILNRNAPAFYC
                     VPAKVFEEMMERLEDLELNALADARAGQPVVKVSLDDL"
     gene            complement(19015..19497)
                     /locus_tag="P5537_08620"
     CDS             complement(19015..19497)
                     /locus_tag="P5537_08620"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HRV78145.1"
                     /translation="MSSPLYDIAVERLAGGTTTLGEYAGKVLLIVNTASQCGLTPHYA
                     GLEKLHQTYQDRGLVVLGFPCNQFGAQEPGSAEEIGAFCAKNYGVTFPMFAKIEVNGD
                     GAHPLYKYLKQHAKGILGTEAIKWNFTKFLVSRDGQHIERYAPTTTPDELVKDIEGIL
                     "
     gene            complement(19602..21986)
                     /locus_tag="P5537_08625"
     CDS             complement(19602..21986)
                     /locus_tag="P5537_08625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HRV78146.1"
                     /translation="MTRAAFALLLQTTSSIRLLVLALIGLAGLGWIVVEAGTSSAHEH
                     LRYARDLREIRQVDAELDAAALARRLGLAGDWQGADAHLARMEALIGDLGRVPDFLTD
                     SETAAVHRQLGHYATLQADKRATIGALRVLLDAPPQNGADTETRTEAEADRLLRQLLA
                     QQTAREGERLVESYTDGYSASQTRMHRQRVLLVLAALALGAYLLLTALRLRKVSLSVT
                     QAHADLQEHAAALGRAEAELRLYATVFTNASEGMLITDAHSRIIAANPAFSRITGYSP
                     AEVVGRSPALLNSGRQDAGFYRRMWSTLASRGKWQGELWNRRRDGSIYPEWLSITAVQ
                     GEGNGEEGRPCNYIGIFSDITERKEAEARILHLAHHDPLTNLPNRALLNDRLGQTLLQ
                     ARRDGRGAAVLLLDLDRFKTINDTLGHERGDSLLLEVCARCRRVLRDTDTLARLSGDE
                     FVIVLPDATTADVAADTARRLLDAIALPCRLGEHEISITASIGIALFARDGSDESTLL
                     RNADAAMHRAKEAGRNAFEFYAEDMNTSSLGRLLLEHQLRGAAERGELLLHYQPKVSA
                     ADGRLGGFEALLRWQHPELGMVAPGQFIPLAEESGLIVPIGQWVLEEACRQQRAWLDA
                     GFDVPPLAVNLSAHQLAQPDIVATVAAAIERHHLAPGLIELELTETMLMRDVDRTIRT
                     LVRLREMGVRLSIDDFGTGYSSLNYLRQFPVNALKIDRSFVGDIGSDGAEGKIAAAIV
                     GMAHSLGLEAIAEGVETEAQRAFLQMHGCHQLQGNLIARPAHAREIERFLDRHS"
     gene            complement(22184..22960)
                     /locus_tag="P5537_08630"
     CDS             complement(22184..22960)
                     /locus_tag="P5537_08630"
                     /EC_number="1.18.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003091832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004324 - ferredoxin-NADP+ reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin--NADP reductase"
                     /protein_id="HRV78147.1"
                     /translation="MSSLATERVLSVHHWNESLFSFRTTRDPGLRFENGQFVMIGLDV
                     GGKPLTRAYSIASPNYEEHLEFFSIKVPDGPLTSRLQHLRPGDPIVVSKKPTGTLVLH
                     DLKPGKNLYLLATGTGLAPFLSVIQDPETYERFEKVVLVHGVRFVSELAYTDFITREL
                     PQHEYFGDQVREQLVYYPTVTREPFRNTGRITHVIESGRLFADIGLPALDPARDRVMI
                     CGSQAMNKDCCDLLDGLGFTMSPRIGVAGDYVIERAFVEK"
     gene            23068..23994
                     /locus_tag="P5537_08635"
     CDS             23068..23994
                     /locus_tag="P5537_08635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HRV78148.1"
                     /translation="MRFTLRQIQVFVAVARAENVSLAAESLALSQSAASAALAELESR
                     CAQPLFDRHGKRLRINEQGSLLLPHAVELLDRAAEFEGRMRGEQGLGPLRVGATLTIG
                     NYLLPLIVSDFLQAHPESRVHLQVRNTATIAERLLHHEIDLGLVEGQVVDAELHTEPW
                     VEDELVVFCAPGHALATRGRARVDELAGQPWILRERGSGTRETFDRALRHHPGGVVPR
                     LELEHTEAIKRAVESGLGLGCLSRLALRDALRRGSLVAVEVPELDLRRRFSFVWHRGK
                     YHGAALRRFVEDCRAFTAGARRSDEIPLPPVA"
BASE COUNT         3313 a         7703 c         9222 g         3829 t
ORIGIN      
        1 cccccgatat ccgcatgggc gccgatgaag ccgcgctcga tccgcacctg tccctgcgta
       61 cggctgctcg cgccgatcga ctccagcggg aagccgccct ggtgcagctt ctcgtccaga
      121 ttgcgacgcg tttcgtccca gaatgcggca ttgaaggggt agccgcctgc gtcccagccg
      181 atcggctggc tgcggtattc gttcagcgcc accgcatgcg cgacgtaggc gaactcgtcc
      241 ggaatggcga gacggtagtc cgctgcgaag ggcaggtcgg tgctcagcac ggtgtcgaac
      301 aggcccatga agcgcagctt caccggctgg cagcgcgtga cttcgcgccg agtgccgggg
      361 tcgatggccg ggtagcggat cagctgcctg ccctcgtgtt cgacgagaag ctcggtcagc
      421 gtgttcgcga actcgcgggc ctgcgcggcg ccgcggctga agcccatgac gtcgatgttc
      481 atcacggtgt tgtcgtcgag ggcctcggcc tcgtcgacga agtagtccca catgcgctcg
      541 atgcgttccc ggccagtgta gttgccaccg cgatcgggaa tcgggccgaa tcccttgggc
      601 aggatgtcct cgtaggcctc tcctaggtag tttcttcgcc cgttctcatg gtggcgagtg
      661 cccaccccag agacgtagtt gccgggacca tccgcgtaca ggtcaagaaa tcgaacgaca
      721 ttggtctccg agccgccgag ccgctcgagc tcgctcacct ccgacgagtt gtctgtccca
      781 tcgaacgcaa acaacaccag cccatccgga tccaccctcc cgagcggatt gaacgccgcg
      841 tacgcatatg ggttcggccc gtccggcgtg ccgagtgggt cgggggtgag gtactggccc
      901 tcgcccggat cgtagtagcg cgcgcggttg tagtgcaggc cggtctcggc gtcgaagacc
      961 tggccgggga ggcgcaggtc gagggtgaag tcggggcggg ccggcgaggg ggtgagggtg
     1021 gcggcgccga agggggcgta gcgggcgcgc cagatcggct ggccggccgg gtcggtggcg
     1081 agctcggggg cgccgaggtg gttggtgtgc agccaggcta gaccggcctg cgggtcgagc
     1141 cagctctgca cgatgcggcg caggtcttcg aggaggcggc gcgcggagcc ggtctcggtg
     1201 gcgggctgcg ccgggatgtc gagcacggcg agcggcaggt cggcgagcca gaggtactgg
     1261 cgaaccagcc tgccatcggc gtcgagctcg gcgagcggct gacgggcgtc gtcgtgcacg
     1321 atgtgggtgg tggtgggtgc ggccgtcgcg ggatcgaggc gggtgcgcag gatgcgcagg
     1381 ccacggtggt cgtaggcgta gcgggcgatg ctgcgctcgc cgtcgcggac ctcggtgagg
     1441 cggccgagcg cgtcccatcg caggctgcgc gcgccgaagc gtccgggctg accgctggcg
     1501 tcgtgctcgg cggcggtgaa cgcctcgccc gcccggtccg cggcgaggcc tgccgccgcc
     1561 gggttcgttt ggtgcgggcc cgatgacagc gcacggtggc tggctgccga gaaacgcgtc
     1621 gggcgggtgt tgccggccag gtcctgctgc gccgctgcgc cttcctgggc gaggacacgg
     1681 cgctggtgag ggtcgtaggc gtagcgccac acgccggttt cggccagcgt gccgtcgtcg
     1741 tccctccact ccacgctggc gacgagctgg ttgcggaggt cgtaggcctg gctgcggcgt
     1801 gtcgagggca gcgggccgtc tggttcatgc cggcgttcgt gcagcaggtt gccttccgga
     1861 tcccatcggt actcgtgatc gaggaggagg gggcccgcgt gcgcggcgtt ctcctgcggc
     1921 tgcggtccgg cttcttcctg cgtgctggcg tgcgcatcgg cgcctgtccc tgcggcgtgg
     1981 gccgcggaga tgccgaagat ccgttcgatg cgcgcggcca gcggctggcc gggttcgatc
     2041 ggcagcagcg cgcgcgcgtt gcggagtggg gtgccgcgcg cgtcggcacg cagatgggcg
     2101 acgcggacca gggtgccggc gcgcgtgcgc tcgtgcaccg tgcgcacgcc gttgccggcc
     2161 tggaagctgc gcagtccgaa gaggtcgcgc tcgaacgcgc tggcgatcgt ctgctcgcgt
     2221 gccagcgcgt gcagccagga tgtggccacc ggctggcgct tcagcgcgac gacctggccc
     2281 tggccgttgc gctcgtagcg caggcggctg ccatcgggca gggtggaggc gacgagacgg
     2341 cccgcggcgt cgtgctcgta gcgggtgacc acgacgagtt cgccgtcgtc gcgcttcagg
     2401 ctcacgatgc gcgcgctgcg caagccgcgc gggtcgtact cgtagcgttc gcgcccgttc
     2461 ggatgctcca cttccatcag gcgcgggccg tcgtagcgcc agcgcgtggt ctcggtggtg
     2521 ccgctgtgac cgtcggtgat ctgctgggcg aggatgcgcc cgcgcaggtc ccaggtgtag
     2581 cgcgcgcgat ggccgagggc gtcgcccatg gcgacgaggc ggccggcggc gtcgaagctg
     2641 cgccagcgcg tgccggcgtc ggcgctgtgt tcgaggaccg ctcgcccgaa gtcgtcgtgg
     2701 atgatgcgtg ggcgggcggg cggcgtcgtc gcgatcgcct ggtcgcgccg cgggcggatg
     2761 ggcggcagca gctcccggcc atggctgtcc aggagtccga cgagccggcc ggcgtcgtcg
     2821 taatgcaggc tgcgggtgaa accggtgtcg tcgccgatgt cggccaggcg cccgcgctcg
     2881 tcgtagcgcc agcggcggcg aaggagccgg ctggtgctgc gcagcgcggc ctcgacgacg
     2941 cggctctcgt ggtcgtaggt ccaggtcttc agggcgccga gcgcgtcggc gtgccactgc
     3001 aggcgcccgg cggcatcgta ggcgcgtcgc cagcgcggac gcaggtggtc ttcatcctcg
     3061 ccggtgcgca gctcgacgag attgccaaag gcgtcgtatg cggcggcgtg gcggtgttcg
     3121 agcgcctcgc ccggggagcc gctgctccac tcgatcggct gccccgcggc gtcgtggcgc
     3181 aggcggattt cgtggccttc tgcgtcgcga acccgcagcg gcaagccggt gaccgggtcg
     3241 gagtcgatct cgctgcgccg gccgccgggg ccctcgactg cgcggatgaa gctgccgcgc
     3301 tcgtcccagt gcaggcggac gcggtcgctg tcgtgcgggc tggcgtccgg tccgtcgggc
     3361 agggggccgt cgagctcgac gagcacgctg cgcccgttga tcgtggcgta gcgccagtgg
     3421 aggcggcgct cgatcggcac gggattgggc cggccctcgg tgtcgatcgg gctgaagccg
     3481 gcttcgcgca gctcgacggg ctggcccgcc gcgttgtagc gcagctcgat gcggtgctcg
     3541 cggccgggga tgacgctggc acggatgacg gcgcgcggcg ggggcgtcgc gccaggctcg
     3601 agttcatgcg ccgcgccctc cgaaggggcg tcagcgatcg ccgatgcatc ggcatgctcg
     3661 tggcgagcgc ggtcgagcag gcgcggccgg gcgccggtga ggtcggcgct cagcgtctcg
     3721 acgatgcggc cgtaggcgtc gaagcgatgc tgggtggagg tgcgcggccg gccttcggca
     3781 tccagcgtgg tgaggacgcg cagtcggcca tcgggcgtgt agccgtagcg gacgttcgtg
     3841 gggccgcagc gtgcgcagcc ggggccgcgc acctcgagca ggcggcgctg gccggcgatc
     3901 accgcgccga ggtaggtggt gcgctggccg aggctgttgg tgagctcggt gcggccgcgc
     3961 gccgggtact cgaggcgcac gtcctcgggc ccggtctcgc cctccgccgg caacgcgccg
     4021 cgcaccgagc ggatgccgcg tccggcggcg tcgtaggcat agctggcgat gcgttggggt
     4081 gcgggcgggc cgtcgggctg gcgggcgagc acgctgatgc cggtgagcgc gaccgggtgg
     4141 cgcgggtcct cgtagtggta tgcgcgggcg gcggcccctc cgcccgtcga cgcctgcgga
     4201 ccggggtagt cgacgcggac cagtcttgtg gcggcggtct tgcgtgccgt gcgactcttt
     4261 gcgggtgccc cgcgcttgct ggccgggctc ctgtcgctgg aagtcatctg cctgccgtgc
     4321 aggggacctg gtccggctgt cgcgcccgcg tgggtgcgtg tggggatcgc gacgctctcc
     4381 tgtgtgaacg agaagcgccc gagcggactg tcgatatgcg cgatgccatc cgagccgttg
     4441 ccccgaggag ggtaatgcag ctgcaggctg cggccctgcg gatcggtgac ctgcacgagc
     4501 cgacccgcct ggtcgtggcg cagcgagacg aactcgccgc tcggcagcag gatctggacc
     4561 agtcggccag cgtggtcgaa caggaggctg cggccgtcgg gccagcgcca gaggtattcg
     4621 tcgccgctgg tgcgggggcg gatgcggatc tcgccgcggc tggggtcgcg gctggcgcag
     4681 cgctgcggct cgccgggccg gcgggcgaag atcacccggg tgccgtcggc ctggagaatc
     4741 tcgagccgat cgtcgcggat gtcgaggcgg gtctcgtagg acagccgcca gccgctgccg
     4801 agcgcaccgg catcgcccag gcgggcacgc cagctgttgt agtggcggac gatctcgagg
     4861 ccgagcacgc caggcagcgc cgggaggtcc acctcctgct ggtacttgtt acccgagagc
     4921 acgtcgatcg ggttccccgc gccgaggtcc tggccagtgg ccgatccctg gctggccgga
     4981 ccgctggcgt tgccgcaggg gttgccggcg ttgttggcga cgcattgccc cgccgcgggg
     5041 ggctccgggg ccgcggggac cccctgtgtg gtgtccggtg cgcagttcat ggtgattccg
     5101 cacccgctct gctggatgcc gcccagcgcg acgcccgatt gcgaggatgc ggtcccggcc
     5161 gccaggccgg ggcgcaccga gaggaagagc gccgccagca gcgcggtgcc cgccagcatc
     5221 gcacggtgcc ggcgaccgac ttgcgcgtgc tggcttgcgt gcgagccgaa aaccggctgc
     5281 cgtcgaacgg gcgtcgtcgg gcaggagagt gccgatgggg gcttgcagcc agacgtcggc
     5341 gccgcgatca gcattcaggt tcctcctcgg cggcgtcggt gtcctccgca tcctcggtcg
     5401 ggtcggcggt gtcggcttcc ggcccggttt ccccgtccga tgccgtggcg tcgtccggcg
     5461 ccccgttctc cccggccgag agcggtgttt gcggtggcgt gtctggggtg gctgggtcgg
     5521 gcgtgcacag aggatccgtg ggggtgcagc cgggcaaggg cgtcgctgcg ggagcttggg
     5581 agtcgccgcc agctctcgtg cgcggccgga tcgcatcgtt ctcgatggcg tccgactgca
     5641 tgcgcagcgt gacctggctc accatcggga tgcgaccggc ctcgaccagg ctgcggcgga
     5701 aggtgtcgtc gtcgtccgga tcgagcgtgc gcagcgccca ggtgaagaat cgtccggcga
     5761 ggggaacctg cttggccggc ggcagccccc aggtcacgcg cagcttgagc aggttggcgt
     5821 cggccagtgt ctggcccgag cggttgcttg ccggatccgc gttgcagttc gcgcggtccg
     5881 cgggacagcc gagcacgccc agctgggcgg atggaagcac tcgtgcgctg gtttgcaggc
     5941 gttgcgcggc cgccgggcta tggtagtcgt cgaagctctc gcgggtgggc gagacgatct
     6001 cgatgcgcag ggcggtggcg agatcgagct gggcggcggc gaaggagtcg gcgatctcgg
     6061 ccaggtcgcg accgccgccg tagtaggagg tcatcgcgcg tgcaaaggcg aggcgcatgc
     6121 tcgccagccc ggcgtgggcg acgctcccgg cgcgcgcggc ctcgaagctg gcgtaattga
     6181 cgatgctgcg ggcgtggtag gcgagccccg tctggagcat ggccagtgtg agcgcaagca
     6241 gggcaggcgc gacgatgacg aattcggccg caccggcgcc gcggaggacg cggcgtcggg
     6301 atcctggaag aggccgtcgc tgcggcggca acggtggggg cggacgcatc atgcgtgggg
     6361 cgcggcacag atccgtcgcg cgctccgccc tggagcaagt ccctcgcgcc gcgccgcgcc
     6421 gggtgccatc tcgagcacgg cggcggcgcc caagcaatgc gcgacccgcc agggcgcgag
     6481 cgcctcgcgc accgcgagaa ccgtgccacg cgcgtcgatg aacaccacgt cgatggcgaa
     6541 gcccatcccg aaggtgtgga ccgaccagca ggggtcgatc agcaaggcct cgtcggcggc
     6601 gagggggccg cgtccgagca ggccgcgggt gcgttgcagg aagctgcggg cgacgaggac
     6661 gcgcatgctc agagtcccat ggtcatgaac ttcaccgcga tcggaaagcc gagcacgatg
     6721 aaggtgcagg ggaagatgca ggcgatcagc ggcagcagca tcttcaccgg cgcctccatc
     6781 gccgccttct cggcgcgggc gaagcgctcg gcgcggcgct gctcgccctg cgcgcgcagc
     6841 atcggtccca ggctcatgcc catgttctcg gcctggatca cggtggagac gagattcgcg
     6901 atcgccggtt cgccgacgcg ctcggccagg ccacgcagcg catcggcgcg cgacttcccg
     6961 gcacggacgt cgcgcagcac gcggtgcagt tcctcgcgga gcgggcctgc gggacccttg
     7021 gccgcagcct gctggagtgc gccggtgagg ttgagcccgg cttcgacgca aagagtgacg
     7081 agatcgagca cgaaggggag ctgcttgagc atcagccggc gtcgcgagcg gatgcggtcg
     7141 tcgagccagg accaggcgat caggatgccg gcggcggcgc ccgccagcgc cggaatcgtc
     7201 gcgggcaacc cccaggcatg ggcgaacccg aggccgatgg cgagtccgca cagcgcgacg
     7261 acggtgcggt gcgcgagcag ctgtgccggg gagattgtgt agtcgagccc ggccaggcgc
     7321 aggcgtacgg caagccctgc ctgcaggcgt cccggcagca gcggagcgat caggtgcgcg
     7381 atccagcgcg tgggccacca cagcaggcgc aggaagcgag gcggtgtgtc gagccaggtg
     7441 cgatcctcgg gctggaccgc accgacgcta cgcgcgagcg cagtgacgat gccggcactg
     7501 ccgaggccgg cgagcagggc caccgccgcg atcgccgtgc gttcgtcgag cgcaagcatt
     7561 tgagcgaggt tcatacgtcg atcgccacga tgcgccggat cagcagcacg cccagcacct
     7621 cgagcgtggc gatcaccgcg agcgtcgccc agccgggcgg cgagtgccac aggaaggcca
     7681 tcgcctccgg ctccatgcgg tcgagcacca gcagcagcgc gagcggcagc atgccgacca
     7741 ccaccgcctg cagcttgccc tgcgccgtga gcgcaccgat cttcccctcc attgcgagct
     7801 ggctgcgcac cgtgagtgcg gcgcgctcga gcgcttcggc caggctgccg ccggtctcgt
     7861 tggcgatccg catggcggcg atcacgaggg tcagcgaggg caggcgcacg cgctcggcga
     7921 gatggtcgag cgcttcgtcg agtgggatgc cgaggcggtg ctcgcgcagg gtgaggtcga
     7981 actcctgggc gatcggcggg cggccttcgc ggacgagttg ctgcagcgcc acggtcatcg
     8041 acacgcccgc gcgcagcccg ccggcgatga cctgcagcgc gtcgggcagc tgctgctcga
     8101 tgagggcgag ccggcgccgg cgcagcagcc cgaaggcgag acgcggcagc agggcgagcg
     8161 cgcccgcact ggcgagcgcg agcagcggct cgccgcttac gagccaggtg ccgacgctcc
     8221 cgaccgtgac cgcgagcagg ttgagcacga agaggcgcgc cgggtccatg aacaggaaga
     8281 gctcctcgag ctgcaggtgg gcctcggcgg tgaagcgttc gcggtagcgt gcgagcgcgt
     8341 tgcccgcgat gcgcatcgcc gaccacgcga gcagggcgga cgcgagtccg aaggcgaggg
     8401 tggccagcag cacggcgggc gaggcggcca gggtattcat gagcggctcc ggtcgaacgg
     8461 gtggaggtcg agcgcgacgc cctggcggcg cagttcttcg tagaagccgg ggaccgcatc
     8521 gcagccggtg aagtggccgc cgccagggtc ggcggcggag tcggcgccgc ggcgctcgaa
     8581 acggaagagt tcctgcagct ggatgcgtcc gccctccatg ccggtgagct cggtgatgct
     8641 ggtgacgcgg cgcgcgccgc aggcgaagcg ggtctgctgg acgatgacgt ccaccgcgct
     8701 ggcgatctgc tcgcggatcg cggcgagggg gagatccatg ccggccatga ggaccagggt
     8761 ctcgaggcgg gcgagcgcat cgcgcgggct gttggcgtgc agcgtggtca tcgagccctc
     8821 gtggccggtg ttcatcgcct gcagcatgtc gagcgcctcg cccccgcgac actcgcccac
     8881 cacgatgcgg tccgggcgca tgcgcagcgc gttgcgcacc aggtcgcgga tgctgatcgc
     8941 gccgcgccct tccaggttgg ccgggcgcgc ctccaggctc accaggtggc tgtggcgcag
     9001 gcgcaactcg gcggcgtcct cgatggtgat gatgcgctcg ccgtcgggga tgaagttcga
     9061 cagcaggttg aggaaggtgg tcttgcccga gccggtgccg ccggagacga cgatgttgcg
     9121 ccgctgctcg acacagatgc gcaggaagcc ggccatgtcg tgcgagagcg agcccatgcg
     9181 cacgagatcc tcgacctcga gtgcccgacg cgcgaacttg cggatggtca gcgtcggccc
     9241 cttgagggcg agcggcggga tgatcgcgtt gacgcgcgag ccgtcgcgca ggcgggcatc
     9301 caccatcggc gaggattcgt cgatgcggcg gccgagcggt gcgacgatgc gttcgatgac
     9361 gccgagcacc gcgcggtcgc tggtgaaggt cgtcgggtgt ggggcgatgc ggccgccacg
     9421 ttcgacgaag atctggtcgt agcggttgac catgatctcg ctcaccgcct cgtcggcgag
     9481 cagggcctcg agcggtccga ggccgatcgc ctcgtcgagc acctcgcggc acagctgttc
     9541 gcggtccagg gccggcggca gcgtggcctc ggcggcgatg atctcgcgca cgagcgcggt
     9601 ggtctcgctg cgcagttcgc cgtccgacat gcggttgaga tcgcgccgac gcaggtcgat
     9661 ggtgtcgagc aggcgctcgt ggatgcgctt gcgccaggtg aagtccgcgt tcgacgccag
     9721 cgtcgacggg cgcggctcga tcgctgcgcg cgccgacgcg tcgggggcgg cttcgaccag
     9781 gccggcacgc cgatccgtcg ccggcgaggc gggggcgggc gtcggctctg cggtcgtgga
     9841 ggggggcctg cgcggggtgc ggaagaacat tcggggctcc ggtcagctgc cgccgtagag
     9901 ggcgttccac gcgggatccg caggttcgcg caccaccggc gcgggctcgg gtgggggcgc
     9961 gagggcctgc tcggcgcggt gttcgagcag ttgtgcgcgc gggtcgagca ggccttcgcc
    10021 gggttcgagc agccacgggg tgacgaagac caccagttcg ctctcgcggt tgttgaagcg
    10081 cgtggagcgg aacaggtgcc cgaggacggg gacctcgccg aggtagggga cggcgttctc
    10141 gtcgctctgc tgttcgcgct gcaacacccc ggagagcacc agggtctcgc cgttgcgcag
    10201 gttgaactcg gtctcggtgc ggcgcgaaag cagcccgggc acgccctggg cggcgacgct
    10261 gcggtcgagc gagctgacct cggtgcggat gcgcgcgcgg atggtgccgg cggcgtcggc
    10321 gaccggttcg aggatgttga ggcggacgcc gtactccttg aacgtcacgc tcggcgtgcc
    10381 ggtggcggat gcgaccggca cggggatctc gccgccggcg aggaagctgg cctcgccgcg
    10441 gttgcgtgcg gagagtcgcg gagaggcgag gatgaccgcg tctcccttct gcgcgagcag
    10501 gttgagccgg ccgaagaagc tgccgacgag ggcggcgttg gcggcaaagg gcgagacgcg
    10561 gtccgcctcg atcgacactt ccgagcgttg ctcgccggtg ccgagcgtgc gcgtcaccgt
    10621 ggcgccggtg cggttgtcgt ggtacaggtc gccgatcacg ccgatgccga gcagcggctt
    10681 gccctgcgtg gtccagtcga tgccgaggtc gcgcaggccg ctgcggctga tctcgacgaa
    10741 gcgcacgtcg aaggcgaaca tgcggtccag gccgacgcgg ctggtgaaat cgatgagctg
    10801 cggaaagcgc ttggcgagct cggccacctt gtcgcgctcg gcgtcgctga ggccttcgcc
    10861 ctcgatgacg acgttgtcgc cgatggtgcg cgtgcgcagc cgcgggacgt cgtgcaggaa
    10921 gccctgcagg tcgcgtgcga tgcgggcggt gtcggtctgg cggacggtga tcttgatgcg
    10981 ctggctgcgg cccgagcggg accacacctg cagcatggtg tcgcccggcc cgttggcgat
    11041 gagcaggatc tcgcgctcgt cgaggaccgc ggcggagagc accttggcgt cgccgaccgc
    11101 gaggcgctgc gcgtcgcgct ggggcagcac gcgcgtctcg ccggcgaaca tctggatctc
    11161 gtggacgacc ggcaaagccg cgcggccggc ctcgatcggc acgctcgccg gtggccggac
    11221 cggcggcgca ggcagggcga ggactggcgc gccgaggagc agggtggcgc acagcaggct
    11281 gcggagaggc ccgcggaggc ccacggggtg gatcggatca gtccgggtca tgggcgggct
    11341 ctgctcgcgg ggcggggcgg gaaaggggag aagaggtcgg gatcagtgcg gggttctcga
    11401 cgccgccgta gatgacgggt acgccaccgg ccgtcggcgc gggtgcgagt ccgagcaggg
    11461 cgagtgcatc ggtgcgcagc agtggcgccg tgcgaatgtc ctggggattg cgcagcaccg
    11521 cggtcaggcg ggccagtgcg cgtgcggcga cgagccgggt cgcctcttcc tccgatagat
    11581 ccagggtcag ggtgccgaag gtgccgccga ggggatcgcc cgcgccaacg tcctcgcccg
    11641 gccgggttcg gctcccggtc gcgagcacgc gtacgccttg caataggggc atggtcaggt
    11701 gctgcttgtc gcgctgaacg gtcgcgagca ggtcgatgcg atcgcccggg cgcagcaggc
    11761 ccgagagcga gctggtctca tcgaccggga tcgtggtcgc gcgtcgaccc ggggcgaggt
    11821 gcgcggagag gctggcgggg cgccgctcct ccagctgcga ccacaccagc ggctcgccgc
    11881 cgcgggccgg ctgggcgagc accgcgcccg cggcgcgctc gaactgctcg ggcgtgatcg
    11941 cgctcgagtg cagccattcg accgggactt cgcggatggc gacgaggtcg tgggtgaggg
    12001 gggtcccgac cgcgaggtcc gtcttggcga cgaccgcacg acccatctgg ccttgctggc
    12061 gcagttcgat ctcgctggcg cgctcttcga ggtagcgtgc ggcgagccat gcggcaccca
    12121 ggccgaagag ggtggcgacg gcaagaatga tcaggttgcg ggggactctc ttgggcatga
    12181 gcgggtcaga tggggagtga aatgctgctg agaaagcgcg cgaagccggt cgccacggcc
    12241 tcggcaaaaa agaggacgag cggcttgcca tcgaatgccg gaagcgcgaa gacgccgagc
    12301 acgatggaga ggatcagcag atgctcggtc atcgcctggc cgcgcaggtg tgggatctgc
    12361 ctcatcgccc gtcctgcacg ccgtggtcga tcatctgcag cgtcaccgtc gtcccgctgc
    12421 cgtggcgggt gacggtcgcg accgcctcgc ggccgcgggc gccgaaccaa agtccaaggc
    12481 cttccaggcc gggccgggtg accgggacac ggcgctcgag cgcgagaccg aggatcgaaa
    12541 gctcgcgtac gaggcgggcc gcagcccagg agggcgagga ttcgtcgtgc cagaccagga
    12601 tgcgtgcccg gcgaccgcca tcgttcgtct cgagatcggt gctgagcagg ctgtccgctg
    12661 gccggcctgg agctggcgac gcgggggccg cggcgagtga gagatcggac tcggacaggg
    12721 tgccctcggt gcacggggac agcgctgccc ggcatggacg caggcgcaag gtgcgcaagg
    12781 ccgtgccctg cttccaggaa aggatctccc agtcgtcgat gcgcgcggtc aagggcttgc
    12841 cctcgaccgc tttctggtag aaggcgcgca cgccggctgg cgaggtctct gcctcgaact
    12901 ggcggattcg ggtcggcacg ccgtggacgc gggcgtcgtc gattaccggc gtgatgcggg
    12961 ctccggccaa gggcggcaag ggttcgggca gggcggctcc ggcgtggggg ccggccagca
    13021 gggtgaaggc gacccacagg cctgcgagcg cgccatgatc ccgcccttgg gggcggggat
    13081 tggaggtcgg gtgaggcgaa gcaactcgcg ctggcatgtt cagcaccctt cttcgagacg
    13141 gtcgcaaggc aggatctcgg cttcgacgcg tccgacctcg atcgcctcgt cgagcaccag
    13201 cggtggcagg acgcgcccga ccgtgttgcc gatcagcgcc agcggctgga tcgggtaggc
    13261 gagcgggccg gcgtcttcga tccggcgggc gtactcggcc gaacccgccg ccgaccagtt
    13321 gtgcccgagc aggacctgat gacgatggat cgtcagcccc agcgtgtcga agggcgccag
    13381 gccggggacg ttgcgtggag acacgcggat cgttccggtg tattccgtgc cggcgggcag
    13441 gtcgagcccg agcgatccgg cgagcagggc cgatgcgggt gcagtgtcgg tgtgcgagcc
    13501 gagctcgacg ccgacccggc tggccggatc gctgaggagg tgttcgccgc gatgatcggt
    13561 ccacaacggg ttggccggac gtccgcttgc ggtggcgtcg gcgggccggc tgaggatcgg
    13621 tgccgcgctc ggcgaaaaga tgcgctcgcg gacctgggcg gcgagcgcct ccgccgtggg
    13681 tgtgcgccgg gcagggcccg tgatcgcggt ctcgaaggcc acgtagcgtg cggcctgctc
    13741 ggtggtgtgg gcgaggtcga gatacttgcc gagcaggggc aggctcatga agagcggcac
    13801 gaggaccagg gcgagcacga ggaactcggt cgtcgactgg ccgctttctg ctgggcgcgc
    13861 aatcgcgagg agcaagtggc ggggcttcat ggcagcgcca tcccttcctg ccgcccggcg
    13921 gcccaggcac ggtccgtcgg ggtcacggcg gtgagcctgg catgccagta aggactgtac
    13981 aggctcgccc gctcggtctt gtggtcgctg cgcgccgcgg gacgctcgaa gaagacctcg
    14041 gcgcgcgcca tcgcggcgag gtggccgccg ggggcggtcg catcgaacgc acgcaggttt
    14101 ccctgcggtt gcacgctgcc gatccccccg gagccgcgca gcctatggcg tgccttggcg
    14161 acgtggacgg tcacgccgga gcggtgatcc gcggtggcgg agaggtcgcg cagttcgcgg
    14221 gtttccggca gcccgctgaa gcgcgctgcc cccgcgtcga cgatcgcagg ctcggccagc
    14281 ctcagcgtcg tgatcggatt gctcgtgtag gtgttgccgt gatggccccg ccgcgcatcg
    14341 gcttcctcgt cgcctgcgaa gctcgcaccg ccccaggcga gcggcgtgcg acgccagcgc
    14401 cagcgccagc gcttcatccg ctggccctgg tgttcgagcg tgtcgagcgc gcgccattcg
    14461 tcgtaaccga tcagctcggt gccgccgcgt cgcttgagtt cgaccttgcg ctgcaagggc
    14521 gggaggttca agccgcggat cgaccacacg cgctcgcggg tgaaggcgtc gcgggagcgt
    14581 agcgtgacgt cggcgatccg ttcgcgcgca tctccttgcg cggagtccct cgccatggcg
    14641 cgggtcaggt tgcggaagtc gtggctgatc gggttgatcg aggcctgcat gtcggggtcg
    14701 atccgatgca cgaattcgtt tgcgaacccg gcctgggcga tgcccgtgtc caggctcgcg
    14761 tgcatcacgc gctgcgagag cgacagcgcg ttcgcgactg cgtcgtgggc ggttgcgatc
    14821 gcgcccagcg cggtatcgag gccctccacg atggcacgca gcgagccgcc gctcccgacg
    14881 tccaggtagg cgctgccatt gaccccggcg agcagttgca ggagccgcgg gtactcgccg
    14941 ggcttgtaca gccagctcat ggccacctgg ttcagggcgg gagcgctccc gaccgccgtc
    15001 tcgaagtagt gcatccacga gatcaggctg atcgcctgcg cgatcgcgac ctcgttggcg
    15061 acgatggccc ggttggtgta cgcgtcgtag ttgagcgcgc gtgcctcgag agtggcgacg
    15121 ctccaggcgg tggcgtcggc ggcattggtg aggcgcagct tttcgtccac cgtcctgccg
    15181 ccgttgaaca tcagcagcag cacggccgcg gtggcgaaga cgaagaagag cccgagcacc
    15241 agcgcctggc cgcgctgcgg ggccgccccg ggcgagtgcc ttccgacacc ggggcgcggg
    15301 aacacgacca tgcgggtgcg ctcggggagg ctgtagcggc gggccgaact cagcggcccg
    15361 cgttgccggt gtaggtgtcg agcgtgcggg ccgtgttggc ctcggtcgcc gccttgccgg
    15421 ccgcggtttg cgcggcgctc ttggcagtgc cgccgtcctt gccggcgatc tcggtggcga
    15481 tcgcggcggt ctggttgcgc accgtctgtc cgaagtattg atagaccgcg atcgctccga
    15541 ctgcgatcag cgccacgatg atgatgtact cggtcatgcc ttgaccgcgc tgctgcccga
    15601 gtccgctgcc tgccgccatg atcgcctccc gccggtaaat gatgaagaaa taatgacaaa
    15661 cgggatgggt cgagtcaata tgcaaataag attccttgcg cagcgtcgcc ggggggggta
    15721 aacgcgaaag cccgctgcag ggcatgcagc gggcttccat ggagcggctt cgtccggtgc
    15781 cggctcagcg cgcgatcggc ttgtagcgga tgcgcctggg cttggcgcct tcctcgccca
    15841 gacgcttctt cttgtcttcc tcgtattcct ggtagttgcc ctcgaagaag aaccactgcg
    15901 agtcgccctc ggccgcgagg atgtgggtgc agatgcggtc gaggaaccag cggtcgtgcg
    15961 agatcaccag cgcgcagccg gcgaactcca gcagcgcgtc ttcgagcgcg cgcagggtct
    16021 cgacgtcgag gtcgttggac ggctcgtcga gcagcagcac gttgccgccc tggatcagcg
    16081 tcttggccag gtgcaggcgg ccgcgctcgc cgcccgacag gttgccgacg atcttctgct
    16141 ggtcgccgcc cttgaagttg aagcggccga tgtaggcgcg gctgggcatc tcgaagcggc
    16201 ccacggtgag cacgtcggcg ccgtcggcga tggcgtcgaa cacggtcttg tcgttggcca
    16261 ggccctcgcg ggtctggtcg accgcggcga tcttcaccgt ggcgccgatc tcgaccgtgc
    16321 ccgagtccgg cttgtcgcgg ccctcgatca tcttgaacaa cgtcgattta ccggcgccgt
    16381 tggggccgat gatgccgacg atggcgcccg gcgggatggc gaagctgacg ttgtccatca
    16441 gcagcttgtc gccgaaggcc ttgctgacgc cgtggaactc gatgaccttg tcgccgaggc
    16501 gctcgccggg cgggatgaag atctcctggg tctcgttgcg gcgctggtat tcgacgctcg
    16561 ccatctcctc gtagcgggcg aggcgggcct tggacttggc ctggcgcgcc ttggggttgg
    16621 agcgcgccca ctccagttcg gtcttcatcg ccttctggtg cgcggcttcc tgcttggcct
    16681 cctgcgccag gcggtcgccc ttctgctcga gccaggacga gtagttgccc ttccagggga
    16741 tgccgtggcc gcggtcgagc tcaaggatcc actcggcggc gttgtcgagg aagtagcggt
    16801 cgtgggtgac ggcgaccacg gtgccgggga agcgggtgag gaactgctcg agccactcga
    16861 ccgactcggc gtcgaggtgg ttggtgggtt cgtcgagcag cagcatgtcg ggcttggaca
    16921 gcagcagctt gcacagcgcg acgcggcgct tctcgccgcc ggagagcttg ccgatcacgg
    16981 cgtcccaggg cggcaggcgc agcgcgtcgg cggcgatctc catctgggtc tcgacgtcgt
    17041 tgccggcggt ggcgaggatg ttctcgtacc tggcctgttc ctcggcgagc ttgtcgaagt
    17101 ccgcgtcggg ctcggcgtag gcggcgtaga cctcttcgag cttctggcgc gcctccatga
    17161 tctcgccgag cgcggactcg acctcttcct tgaccgtctt ggcggggtcg agctcgggct
    17221 cctgcggcag gtagccgatg cgctggccgg cgagccactg cacctcgccg tcgtactcct
    17281 tgtccacgcc ggccatgatg cgcagcacgg tcgacttgcc cgagccgttg aggccgagca
    17341 ggccgatctt ggcgccgggg aagaaggaga gggagatgtc cttgatgatc tgacgcttgg
    17401 gcggaacgat cttgctcacg cgcagcatcg acatgacgta ttgggccact acgggtacct
    17461 cgttgacggt gttcggtggg gcggaaaagg gcggagtcta cccgagtggg cagcggccgg
    17521 cacgcatgga gcttgccgct agccgattgg ggtattacgc tgaggcgacg tgtaagaaat
    17581 acaggaagga gagaatcgag atgcacacca cactgacgag caaggggcag gtgacgatcc
    17641 ccaagcacat ccgcgacgcg ctgcatctcg agcccggatg cgcgatcgag ttccgcatca
    17701 atcgcgaggg cgaggtcgtc ctgacgcgcc ccggtgaact gcgagacgag gctgatcgct
    17761 tcgagcgcct gcgcggcaag gccgacgtca agtggcgcac ggacgacctg atggccttgc
    17821 tgcgtggcga cgactgatgc tgctggtcga caccaatgtg ctgatcgatg tgctggaaga
    17881 cgacccgcgc tgggcagatt ggtccatcga catgctgcgt cggcagtcgc aagtgcatcg
    17941 acttgcgatc aatcccatca tctacgccga actttccttg accttctcga ccgtcgaggc
    18001 gctggaggag gcggtcaccg atttcggcgt cgaagtcgtc gagatcccca ggccggcgct
    18061 ctttctcgcg ggcaaggcct tcgtcgccta tcgccgtaac ggcggccagc ggaccaacgt
    18121 tctggccgat ttcttcatcg gtgcccatgc cgcggtcgaa ggctggccaa tcctgacgcg
    18181 cgatccgcgc aagtatcggc agtatttttc gtcggtcgaa ctcgtggcgc cttgaggcgt
    18241 gcaggggcct ccggtggcct ttactgcgtc agagcgtccg gcaccaagct cgagagatgg
    18301 gcaagcaagc tgtcgtcaga agtggcgtat gtctcgttgg agccacaccg gtgcctcgtg
    18361 cgttcagcgt cgtgccgccg ctcgatagac tgcgctgcgc tcccgcttgc cgacagcgac
    18421 caccaccacg atgagttctt cgtcccgaac ttcgtggaac agccgatagc ccacgctgcg
    18481 cagcttgatc ttgtagcggt cggggtgtcc gctcaacctg gcggccggca cacggagcgc
    18541 gtccaggcgt tcggcgagct tgttcttgaa ctgttcgcgg atgcttccat cgagcttgcg
    18601 ccactcggcc aaggcctcgt cgacgaagcc caactcacaa gtcatcgagg ctcaccttga
    18661 cgaccggctg gccagcgcgg gcatcggcga gcgcgttcag ttcaagatct tccagccgtt
    18721 ccatcatctc ttcgaacacc tttgcgggaa cgcagtagaa ggcgggggca ttgcggttga
    18781 ggatcgcaac cgggaagcct tccccggcag cgaccgtgcc catggggttt ttcttgagtt
    18841 cggaaacgct tgcggtcgtc tcgaccagta tctgatgtgc cattttgagc gtcctgaaga
    18901 ccggatacga gtacgtagaa tagaacttga agtggaggat gcgactccgc ggagagggcc
    18961 cggttttcgc actcgagcgc ttcctccacg tctgagccgg gacgcggatg tggtctaaag
    19021 aatcccctcg atgtccttca ccaactcgtc cggcgtggtc gtcggcgcgt agcgttcgat
    19081 gtgctgccca tcccggctca ccaggaactt ggtgaagttc cacttgatcg cctcggtgcc
    19141 gaggatgccc ttggcgtgct gtttcaggta cttgtacagc ggatgcgcgc cgtcgccgtt
    19201 gacttcgatc ttggcgaaca tcggaaaagt cacgccgtag ttcttcgcgc agaaggcgcc
    19261 gatctcctcc gcgctgccgg gttcctgcgc gccgaactgg ttgcagggga agccgagcac
    19321 gaccaggccg cggtcctggt aggtctggtg gagcttctcc agcccggcgt agtgcggggt
    19381 gaggccgcac tggctggcgg tgttgacgat cagcaggacc ttgccggcgt attcgccgag
    19441 ggtggtcgtg ccgccggcga ggcgttcgac cgcgatgtcg tacaggggcg agctcatggg
    19501 gtgggtctcc gtgcgtggcg tggatgcggg cccgcggcat ggcgggcgtc gcgtgcttgg
    19561 agccgcgccg gccacggcaa gtttccgccg tgccggggga ttcagctgtg acggtccagg
    19621 aagcgctcga tctcgcgcgc gtgtgcgggg cgggcgatca ggttgccctg cagctggtgg
    19681 cagccgtgca tctgcaggaa ggcgcgctgg gcctcggtct ccacgccttc ggcgatcgcc
    19741 tccagcccga ggctgtgggc catgccgacg atggccgcgg cgatcttgcc ctcggcacca
    19801 tcgctgccga tgtcgccgac gaagctgcgg tcgatcttga gcgcattgac cggaaactgg
    19861 cgcaggtagt tgagcgagga gtagccggtg ccgaagtcgt cgatcgacag ccgcacgccc
    19921 atctcgcgca ggcgcacgag ggtgcggatg gtgcgatcga cgtcgcgcat cagcatggtc
    19981 tcggtgagct cgagctcgat caggccgggc gcgaggtggt ggcgctcgat ggccgcggcc
    20041 acggtcgcga cgatgtcggg ctgggcgagc tggtgcgccg agaggttcac ggcgagcggc
    20101 ggcacgtcga agccggcgtc gagccaggcg cgctgctggc ggcaggcttc ctcgagcacc
    20161 cactggccga tcggcacgat caggccggat tcctcggcga gcgggatgaa ctgccccggc
    20221 gcgaccatgc cgagctcggg atgctgccag cgcagcagcg cctcgaagcc gccgaggcgg
    20281 ccgtcggcgg cgctcacctt gggctggtag tgcagcagca gttcgccgcg ctcggcggcg
    20341 ccgcgcagct ggtgctcgag cagcaggcgg ccgagcgagc tggtgttcat gtcctcggcg
    20401 tagaactcga aggcgttgcg cccggcctcc ttggcgcgat gcatcgcggc atcggcgttg
    20461 cgcagcaggg tcgattcgtc gctgccgtcg cgcgcgaaga gggcgatgcc gatgctcgcc
    20521 gtgatgctga tctcgtgctc gccgagccgg cacggcaggg cgatggcgtc gagcagcctg
    20581 cgtgcggtgt cggcagcgac gtcggcggtg gtggcgtcgg gcagcacgat gacgaactcg
    20641 tccccgctca ggcgcgcgag ggtgtcggtg tcgcgcagca cgcgccggca gcgcgcgcag
    20701 acctccagca gcaggctgtc gccgcgctcg tggccgaggg tgtcgttgat cgtcttgaag
    20761 cggtcgaggt cgagcagcag caccgcggcg ccgcgaccgt cgcgccgcgc ctgcagcagg
    20821 gtctggccga ggcggtcgtt gagcagcgcg cggttgggca ggttggtgag cggatcatgg
    20881 tgggcgaggt gcaggatgcg cgcctcggcc tccttgcgct cggtgatgtc ggagaagatg
    20941 ccgatgtagt tgcacggcct gccttcctcg ccgttgccct cgccctgcac cgcggtgatc
    21001 gacagccact cggggtagat cgagccgtcg cggcggcgat tccacagctc gccctgccac
    21061 ttgccgcggc tggcgagcgt ggaccacatg cggcggtaga agccggcgtc ctggcggccg
    21121 gagttgagca gcgcgggcga gcgccccacg acctccgccg ggctgtagcc ggtgatgcgc
    21181 gagaaggccg ggttggcggc gatgatgcgg ctgtgcgcgt cggtgatcag catgccctcg
    21241 ctggcgttgg tgaacacggt ggcgtagagg cgcagctcgg cctcggcgcg accgagcgcg
    21301 gcggcgtgct cctgcaggtc ggcgtgggcc tgggtgacgc tgagcgagac cttgcgcagg
    21361 cgcagcgcgg tgagcagcag gtaggcgccg agcgcgagcg cggcgagcac cagcagcacg
    21421 cgctggcggt gcatgcgggt ctgcgaggcg gaatagccgt cggtgtagct ctcgaccagg
    21481 cgttcgccct cgcgcgccgt ctgctgggcg aggagctggc gcagcaggcg gtcggcctcg
    21541 gcctcggtcc tggtctctgt gtcggcgccg ttctgcggcg gcgcgtcgag gagcacgcgc
    21601 agcgcgccga tcgtggcgcg cttgtcggcc tgcagggtgg cgtagtgccc gagctggcgg
    21661 tgcacggcgg ccgtctcgct gtcggtgagg aagtcgggaa cgcggccgag gtcgccgatc
    21721 agcgcttcca tgcgcgcgag gtgggcgtcc gccccctgcc agtccccggc gagcccgagc
    21781 cggcgggcga gcgcggcggc gtcgagctcg gcatcgacct ggcggatctc gcgcaggtcg
    21841 cgcgcgtagc gcaggtgctc gtgtgccgag ctggtgccgg cctccaccac gatccagccc
    21901 agcccggcga ggccgatcag cgcgagcacg agcaggcgga tgctgctcgt cgtctgcagc
    21961 agcagcgcga aggcggcgcg cgtcacgctc cctgctccgg ggcgtggtgc cggaggacac
    22021 ggagcgagtc ggaaatcgga gaaagcgagg agggcagggc gagcacgggc ggatgctagc
    22081 ggcgcgctct gtcctggaat tgatctagat caaaggttgc gcgataggac acgcggatcg
    22141 ggcgtgccga tccactgtcc gcaaggtctc tcccgcccag acctcatttc tccacgaagg
    22201 cacgctcgat cacgtagtcg ccggccacgc cgatgcgcgg cgacatcgtg aagccgagcc
    22261 cgtcgagcag gtcgcagcag tccttgttca tcgcctggct gccgcagatc atcacgcggt
    22321 cgcgcgcggg gtcgagcgcc ggcaggccga tgtcggcgaa gaggcggccg gattcgatga
    22381 cgtgggtgat gcggccggtg ttgcggaagg gctcgcgggt caccgtcggg taatagacga
    22441 gctgctcgcg cacctgatcg ccgaagtatt cgtgctgcgg tagctcgcgg gtgatgaagt
    22501 cggtgtaggc gagctcggag acgaagcgta cgccgtgcac cagcaccacc ttctcgaagc
    22561 gctcataggt ctccggatcc tggatcacgc tcaggaaggg cgccagcccg gtgccggtgg
    22621 cgagcaggta gaggttcttg cccggtttga ggtcgtgcag caccagcgtc ccggtgggct
    22681 tcttgctcac cacgatcggg tcgcccgggc gcaggtgctg caggcgcgag gtgagcgggc
    22741 cgtcgggcac cttgatgctg aagaactcca gatgctcctc gtagttgggg ctggcgatgc
    22801 tgtaggcgcg ggtcagcggc ttgccgccga cgtcgagccc gatcatcacg aactggccgt
    22861 tctcgaagcg cagcccgggg tcgcgggtgg tgcggaagct gaagagggat tcgttccagt
    22921 gatggacgct gaggacgcgt tcggtggcga ggctgctcat ggttgcgggt ctctgcaggc
    22981 tgcgtgaggt gggaatgggg cgattctagg tcgttctctt tacctgtatc gtggataatc
    23041 ttcatatcct taatcgacgt aatcgatatg cgattcaccc tccgccagat ccaggtcttc
    23101 gtcgcggtgg cccgcgccga gaacgtctcc ctcgccgccg agagcctcgc actgtcgcag
    23161 tcggcggcga gcgcggcgct cgccgagctg gagagccggt gcgcgcagcc gctcttcgac
    23221 cgccacggca agcgcctgcg catcaacgaa cagggcagcc tgctgctgcc gcatgcggtc
    23281 gagctgctcg accgcgccgc cgagttcgaa ggccgcatgc gcggcgagca gggtctcggc
    23341 ccgctgcgcg tgggggcgac gctgaccatc ggcaactacc tgctgccgct gatcgtgtcg
    23401 gatttcctcc aggcccaccc ggagagccgc gtgcatctgc aggtgcgcaa caccgcgacc
    23461 atcgccgagc gtctgctgca tcacgagatc gacctcggcc tggtcgaggg gcaggtggtc
    23521 gatgccgagt tgcacaccga gccctgggtg gaggacgagc tggtggtgtt ctgcgcgccg
    23581 gggcatgcgc tggcgacacg cgggcgcgcg cgcgtggatg aactcgcggg gcagccgtgg
    23641 atcctgcgcg agcgtggctc gggtacgcgc gagaccttcg atcgcgcgct gcgtcatcac
    23701 cctggcgggg tcgtgccgcg gctcgagctc gagcacaccg aggcgatcaa gcgcgcggtg
    23761 gagagcggcc tgggcctggg ttgcctgtcg cggctggcct tgcgcgacgc cttgcggcgc
    23821 ggcagcctgg tggcggtgga ggtgcccgag ctcgacctgc gccggcgttt cagctttgtc
    23881 tggcatcgcg gcaaatacca cggcgccgcg ctgcgccgct tcgtcgagga ctgccgtgcc
    23941 ttcaccgccg gcgcccgccg cagcgacgag attccgctgc cgccggttgc ctgagccccg
    24001 cattcgcgcc ttccggcgct cctacagaaa ccggcgcggc gacgatgtgc gcgcaggaga
    24061 accgccg
//
LOCUS       DAOTIN010000045        23974 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_2473_length_23974_cov_9.041808, whole genome shotgun sequence.
ACCESSION   DAOTIN010000045 DAOTIN010000000
VERSION     DAOTIN010000045.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 23974)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 23974)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23974
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2473_length_23974_cov_9.041808"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            286..1578
                     /gene="serS"
                     /locus_tag="P5537_08640"
     CDS             286..1578
                     /gene="serS"
                     /locus_tag="P5537_08640"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HRV78149.1"
                     /translation="MLDIQLLRTQLDHVAARLATRGLQLDTAAFQALEDERKQLQTRT
                     QELQARRNALSKQIGMLKGKGEDASGVMAEVAQLGDELKACEQALPTLLERMNAFLAT
                     LPNLPQEDVPVGADESGNVEVRRWGTPGTYDFEVRDHVDLGAPLGLDFETGARLSGSR
                     FAFLRGPVARLHRALAQFMLDTHTREHGYTECYTPYIVNGSALYGTGQLPKFKEDLFW
                     VLRGGDEEGLEQYLIPTAEITLTNSVREEVLALEALPIRLTAHSPCFRSEAGSGGRDV
                     RGMIRQHQFDKVEMVQIVEPAKSNEALEQMVGHAEAILQKLELPYRVITLCTGDMGFG
                     AAKTYDLEVWLPAQNTYREISSCSNCESFQARRMQARFKNAQGKNELVHTLNGSGLAV
                     GRTLVAVLENHQQADGSIVIPKALVPYMGGVERIEAPL"
     gene            complement(1630..4740)
                     /locus_tag="P5537_08645"
     CDS             complement(1630..4740)
                     /locus_tag="P5537_08645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004382088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HRV78150.1"
                     /translation="MRHVSLLERLAGHKVAANVLMLLAFVLGTIGITRMNVQFFPTFE
                     LDVISVRVVWTGASAEDVEIGITAPLEERLKTVDGLKKMSSTSAQGVASITLELHEDT
                     DALLALDQVRQRVDEFRNLPRDAETPEVSRVSRYEPIARLLVRGGSIEELRPWVRRFE
                     SELLAAGIDRITLTGLPEERIAIEIPAAALETLGLSLVQVGDRVGQLARDFPAGIAGE
                     ADGAREIRGLEQRRSADAFAPLPVVSDTLGVVRLGEIARLTREPRNNELALFERGDAV
                     VEMQLQRSESGHSLKAARVLEGWLEKTRPTLPPSIHLEVFDEQWQLISERIELLVNNG
                     LSGLVLVVAVLYFFLPGRVAFWVMVGVPTAFLATLALMYVLGGTLNMMSLFALIMALG
                     IIVDDAIVVSEDADTHRHMGEGAAQAALGGARRMLWPVIASSLTTVAAFLPLMMVGGI
                     IGNILGDIPFVMVAVITASLIECFLILPAHLRGALAGAAALEHSALRARIDGGFARFR
                     DGPFRRLVERALAWRGATVAFTFGLMVLAVGLIAGGRIGFVFFPTPEGQVIYANATFV
                     AGTPRAHTEAFLGELERALFAAEAELGGDLVQTAVARLGGTISSGSGSSARGDQLAGI
                     MVELVPPDTREVRNERFLAVWREKLPTVAGLELLTFTARQSGPPGRDINIRLTGDDAD
                     ALKTAALELAETLKSIPGVSEPEDDMPYGREQLVYRLTPAGEALGLTTESLGRQLRAA
                     FDGALAQLVQVGRDELEVRVMLPREERSRLDVFERINVSLPDGRFVPLATVASWESRR
                     GFEALRHAQGRLAVEVSAAVDSHVSNANVVQAELERDTLPQLAHKYGFEFSFEGRSAD
                     QRETMADMKAGLVLGLGLIYLVLVWSFSSWSWPLVVMSAIPLGLAGAIFGHWLLGIDL
                     TILSMFGLFGLAGIVVNNSIILVSLFKELQHKGAALQEALVGASCGRLRAVLLTSLTT
                     VGGLTPLLFERSLQAQFLIPMAASIAFGLGFSVVLVLFFVPALLSMLESLRAWMAGAP
                     REAAAG"
     gene            complement(4737..5975)
                     /locus_tag="P5537_08650"
     CDS             complement(4737..5975)
                     /locus_tag="P5537_08650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HRV78151.1"
                     /translation="MRRLLPVLILVLAATGFLALRATRPAPPAVEARERVWRIEAEPL
                     AAIAVHPTLVLYGRIEAPDRVRAAAPVGGRVLEVTVRDGDRVAAGAVLARMDPRDLKP
                     RVDQAAAELERERIRHRHDQEAIAQERTLLELAEAKLARFERLKNARLGAESAFDQAR
                     EEVARVRLSLTQRRQAIAEHPARLAQLQVRLAEARRDAERGEVVAPFAARIGKVEVAA
                     GDHVQPGQALLNLYPSDALFLRARVPAIYAEELRSALSRGEALRAHAEFGTSRLGARL
                     ERIGGEADARGVDVLLRMDDAARLPVGAFLNAVLERPRLEAVFPVPPSALHGGDRIYR
                     VEDGRLRAVPVVRAGERRDGERLVMLVRARDEAAPLREGMLVSRTHLPHAIDGLAVEV
                     VGDTVVGAQGSGGEAAGAAR"
     gene            complement(6046..7047)
                     /locus_tag="P5537_08655"
     CDS             complement(6046..7047)
                     /locus_tag="P5537_08655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaJ C-terminal domain-containing protein"
                     /protein_id="HRV78152.1"
                     /translation="MSDPHALLGLPAGASAQQIKRAFRKLAMQWHPDRNPDPAAAEQF
                     RRLRDAHDRLLSTLLGDEGQAPHEDEAAAEAAPQRGADRWQTLEISIEDSFAGALHAV
                     EVERRSPCTQCGGSGIERLSVSRLCTPCRGSGRVRGPAGLERCPDCEGRGYRNTGPCG
                     GCDGSGEQLQTRRLEVRVPPGVVDDDELRLAGEGEPHSDPLHRAGDLRLRIRLASHPL
                     FRREGRDLVLRRPVSALRLLIGGTLRVPHPEGVRNIELEPGLAHPRSLRVPGAGFPAH
                     GRRACGDLVVEFEPELPHTPEPSLHGLIDELDRALAARAEHHFPELARWESVWLDER"
     gene            7245..8084
                     /locus_tag="P5537_08660"
     CDS             7245..8084
                     /locus_tag="P5537_08660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HRV78153.1"
                     /translation="MSRPRASDIPPRDLWVDHPQGRIFAREWNPPGGDAVGAASPIVL
                     FHDSLGCVELWRDFPAALSVASGRRVIAYDRLGFGRSDAREALPELDFIAEEARVYFP
                     AVREQLGLERFVVFGHSVGGGMAVNCAAAFAGACDALITESAQVFPEDLTLSSIAAAK
                     GQFVDESQLQRLARYHGDKARWVLDAWTESWLHPGFAAWSLKSVLPQVRCPVLAIHGM
                     HDEYGTSVHPETIGELSAGPAQVAILPDTFHVPHRERPEAVIELVCAFLEPVRRGKAA
                     CAS"
     gene            complement(8177..8253)
                     /locus_tag="P5537_08665"
     tRNA            complement(8177..8253)
                     /locus_tag="P5537_08665"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8217..8219),aa:Arg,seq:acg)
     gene            complement(8296..8372)
                     /locus_tag="P5537_08670"
     tRNA            complement(8296..8372)
                     /locus_tag="P5537_08670"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8336..8338),aa:Arg,seq:acg)
     gene            complement(8435..8524)
                     /locus_tag="P5537_08675"
     tRNA            complement(8435..8524)
                     /locus_tag="P5537_08675"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8488..8490),aa:Ser,seq:cga)
     gene            complement(8666..9016)
                     /locus_tag="P5537_08680"
     CDS             complement(8666..9016)
                     /locus_tag="P5537_08680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HRV78154.1"
                     /translation="MSKSHVQLIGDVSKALATLRKEIPETMHGFGAMAKSSLQDGALS
                     ELQKELIALAIAVSQRCDACIGFHIKALIRLGATREQIMETLGVCTYMGGGPALMYAA
                     EAVRAYEEMLPQAK"
     gene            complement(9145..9954)
                     /gene="folE2"
                     /locus_tag="P5537_08685"
     CDS             complement(9145..9954)
                     /gene="folE2"
                     /locus_tag="P5537_08685"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003933 - GTP cyclohydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0035998 - 7,8-dihydroneopterin
                     3'-triphosphate biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase FolE2"
                     /protein_id="HRV78155.1"
                     /translation="MNAPTAIAIPDVQSSADSRRIAIDKVGIKSIRHPIKVADKRGGV
                     QHTVASFNMYVGLPHNFKGTHMSRFIEILNGREREISVENFEPMLRTMVERLEAETGH
                     VEMSFPYFINKTAPVSGVQSLMDYEVCFIGSIREGGVYEFTMKVVVPVTSLCPCSKKI
                     SAYGAHNQRSHVTVTAVLNDHLWIEEMVQMVEGQASCEVFGLLKRPDEKWVTERAYDN
                     PKFVEDMVRDVAGELNREPRIDAYVVESENFESIHNHSAYALIERDKRRDA"
     gene            complement(10061..11929)
                     /gene="dxs"
                     /locus_tag="P5537_08690"
     CDS             complement(10061..11929)
                     /gene="dxs"
                     /locus_tag="P5537_08690"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HRV78156.1"
                     /translation="MAPYPNLERIGCPADVRALDRRELGALATELRAFLIESVSKTGG
                     HLSSNLGTVELTIALHHVFNTPYDRIVWDVGHQTYGHKVLTGRREAMSGLRHFGGISG
                     FPRRSESEYDTFGTAHSSTSISAALGMAVAARARAEDRHAIAVIGDGAMSAGMAFEAL
                     NNAGDMENLNLLVILNDNEMSISPPVGALTKILARMMSGSTYNTARRVGEKVLGVAPP
                     VAELARKVEEYAKGMIGPGTLFEEFGFHYYGPIDGHDLDALIPTLQNLRKLKGPQFLH
                     VITRKGQGYKLAEADPVLYHGVSKFDHTAGIQAGKSGGKLTYTQVFGDWLCDMAKADP
                     RIVGITPAMREGSGLVRFAQEFPERYFDVGIAEQHAVTFAAGLACEGFVPVVAIYSTF
                     LQRAYDQLIHDVALQNLPVVFAIDRGGLVGADGATHHGAFDLSFLACVPNLVVMAPTD
                     EDECRQMLYTAVQHPGPSAVRYPRGGGNGTVPQAQMRALPIGKGEVVRHGRGIALLAF
                     GSLLGVAREVAETLDATVANMRFVKPLDAELVAELAASHELIVTLEESAVIGGAGAEV
                     ARVLDSLAARPRVLRLGLPDHFIDHGDQGQLLASVGLDRAGILASIERATGAAPKA"
     gene            complement(11979..12887)
                     /locus_tag="P5537_08695"
     CDS             complement(11979..12887)
                     /locus_tag="P5537_08695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HRV78157.1"
                     /translation="MNADSKLPSFSEWTAQIQQRTEVALAGVLPDPAVAPQRLHEAMR
                     YAVLGGGKRVRPLLAHAAGALAGAAAEDLDRIACAVELIHAYSLVHDDLPCMDDDVLR
                     RGKPTVHVEFDEATALLAGDALQTLAFQVLAERPLGTEPANQLAMLNQLAVASGSRGM
                     AGGQAIDLAAVGKRLGREELEFMHIHKTGALIRAAVLLGARAGAALDAGELERLDHYA
                     KVVGLLFQVVDDLLDAEADTATLGKTAGKDADNDKPTYVSLLGLVDARRLAEEMLDDA
                     RASLRPFGARALRLEQLADYIVHRAF"
     gene            complement(12884..13138)
                     /locus_tag="P5537_08700"
     CDS             complement(12884..13138)
                     /locus_tag="P5537_08700"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HRV78158.1"
                     /translation="MPKSASSPKSFEAAVSELEAIVQEMESGNLPLEDALARYQRGVG
                     LLRHCQATLGDAEQRVRMLEGDGLTDFPTDSSRDGDQAGA"
     gene            13265..14371
                     /locus_tag="P5537_08705"
     CDS             13265..14371
                     /locus_tag="P5537_08705"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic ring-hydroxylating dioxygenase subunit
                     alpha"
                     /protein_id="HRV78159.1"
                     /translation="MSDIASKAQLAQAASQLPVSWYFDQKVFELEKKLLFDAGPGYVG
                     HELMVPEVGNYRSLEWLDHSKLLFRTEAGVHQMSNVCRHRQAIMLQGSGTTKHVVCPV
                     HRWTYDRQGNLLGAPHFPEKPCLGLRRDELERWNGLLFKGPRSAGADLAGMQVAGELD
                     FSGYKLDKVEIHHCNYNWKTFIEVYLEDYHVVPFHPGLGNFVTCKDLTWQFGDWYSVQ
                     KVGITSLAKPGSATYAKWHKAVLDYYGEKRPTHGAIWLTYYPNIMVEWYPHVLVVSTL
                     IPTDIDRTTNVVEFYYPEDIAEFEREFVDAEQAAYMETAIEDDEIGERMDRGRRALMK
                     EGRNEVGPYQSPFEDGMQHFHEFYRRIMEPHIGG"
     gene            complement(14487..15425)
                     /gene="ispH"
                     /locus_tag="P5537_08710"
                     /gene_synonym="lytB"
     CDS             complement(14487..15425)
                     /gene="ispH"
                     /locus_tag="P5537_08710"
                     /gene_synonym="lytB"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051745 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate reductase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA];
                     GO_process: GO:0050992 - dimethylallyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HRV78160.1"
                     /translation="MNDKEILLANPRGFCAGVERAIEIVERALKRYGAPIYVRHEVVH
                     NKFVVDDLRAKGAIFVDELDEVPAGNTVIFSAHGVSLAVREEAERRGLRVFDATCPLV
                     TKVHVEVARMRDQGKEIVMIGHKGHPEVEGTMGQVDGGIHLVETPADVAALQVSDPDQ
                     LAYVTQTTLSVDDAAAIVDALRARFPRIVGPKKDDICYATQNRQDAVKFMTPHADVVF
                     VVGSKNSSNSNRLREVAELRGVPAYLIDNADGIDPAWIEGKRRVGVTAGASAPEVLVA
                     EVIARLEELSGGKVRNLDGVPERVTFALPKELQDAR"
     gene            complement(15458..15886)
                     /locus_tag="P5537_08715"
     CDS             complement(15458..15886)
                     /locus_tag="P5537_08715"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HRV78161.1"
                     /translation="MSEAIQANSLVTLHYRISLPSGQPLISTFNATPATLQLGAGEML
                     PAMERLLIGLMPGTHHVFELAADEAFGPYRDELVERVKREHMPEEEIEAMSIMEFTAP
                     DGSRYSGLVREIDAESALIDFNHPLAGKAIRFEVQVIGIS"
     gene            complement(15883..16407)
                     /gene="lspA"
                     /locus_tag="P5537_08720"
     CDS             complement(15883..16407)
                     /gene="lspA"
                     /locus_tag="P5537_08720"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HRV78162.1"
                     /translation="MSSPAPRNALALMLPWLVLAVLVGVLDQVTKQLVLANLHRGEMI
                     PVTGFFDLVLVYNTGAAFSFLAEHSGWQRWFFTVLALAISAWLLALMHHHRHEKLLPA
                     AFALIIGGALGNVYDRIVHGAVVDFLHFHYAGWSWPAFNLADSAITVGVVMMLWGQLF
                     GPSTGDQPRPGAPS"
     gene            complement(16421..19237)
                     /gene="ileS"
                     /locus_tag="P5537_08725"
     CDS             complement(16421..19237)
                     /gene="ileS"
                     /locus_tag="P5537_08725"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011238327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HRV78163.1"
                     /translation="MADYRKTLNLPDTPFPMRGDLPKREPGWIADWQQRKLYQRIRKA
                     SAGRPKFVLHDGPPYANGSLHIGHALNKILKDIIVRSKTLAGFDAPYVPGWDCHGLPI
                     EHKVEVTHGKNLPADKVRELCRAYAAEQIEIQKADFIRLGVLGDWDNPYRTMDFANEA
                     NEIRALAEMTKNGYVFKGLKPVNWCFDCGSALAEAEVEYADKPSPTIDVAFPVSAAHA
                     DKLAAAFGLAKLDKPAAAVIWTTTPWTIPANQALNAHPEFDYALVDVGDRLLVLAKEL
                     VESALQRYQREGTIVATAKGAALDRIEFRHPFFDRVSPVYLADYVGIDAGTGIVHSAP
                     AHGVDDFNSWRAYGRSNEEILSLVMGGGEYVPDLPFFGGMNIWKANPVIVDKLAEVGA
                     LLSHGKITHSYMHCWRHKTPLVYRATAQWFVGMDRDAADGSTLRERALRAVEATKFYP
                     GWGQARLHAMIANRPDWCISRQRNWGVPIPFFLHKETGELHPRTVELMEAVALRVEQE
                     GIEAWFKLDAAELLGAEAAQFEKISDTLDVWFDSGTTHKHVLRGSHNDGHPEGPRADM
                     YLEGSDQHRGWFHSSLLTGCAIDGHAPYRSLLTHGFAVDGQGRKMSKSLGNVVVPQEV
                     TGKLGAEILRLWVASTDYSGELSISKEILDRVVEVYRRVRNTLRFLLANTADFDIARD
                     AVPLEQWMDLDRYALAFTRQMAQQAEADYARMEFHRIVQALQVFCAEDLGAFYLDILK
                     DRLYTTAAGSLPRRAAQTALWHITQTLLKLMAPILSFTAEEAWAILNPAKAGEEADSV
                     MLHTFHALPAQEGEAGLIARWETIRAVRAEGLKVIEALRTEGKVGASLQAELELALTT
                     DKFAAMVSLGEDLRFVTMTSVAILSEVAGAEHERIVATPSSAQKCERCWHYVDSVGSD
                     AEHPTLCGRCASNLFGAGETRTHA"
     gene            complement(19282..20220)
                     /locus_tag="P5537_08730"
     CDS             complement(19282..20220)
                     /locus_tag="P5537_08730"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HRV78164.1"
                     /translation="MQVHRGIPEHADTAAVLTIGNFDGVHLGHQALLSLLTGKARALG
                     LPAVVLTFEPHPREYFSPADAPARLASLREKLLLLSAAGVDRCHVCRFDARFAAQPAQ
                     SFIDDILVRGLGVRHLFIGDDFRFGARRQGNFAMLQEAGARLGFGVESMPTLTVAGER
                     VSSSAVRAALAAGDLAHAAHLLGRPYSIAGRVSHGDKLGRQLGFPTANIQMKHRRPAL
                     GGVYVVSVEGLAAGPVAGVANIGLRPTATANGRARLEVHLFDWAQDCYGAHIRVHFLH
                     RLRAEQKFSSLDALRAQIALDSLAARDWLAANPLPA"
     gene            complement(20480..21877)
                     /locus_tag="P5537_08735"
     CDS             complement(20480..21877)
                     /locus_tag="P5537_08735"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HRV78165.1"
                     /translation="MRDRTGESFTGRGPGARDDLSLSQASGLASAAEAFAAGRIDRRR
                     LLKLAGASLAMLVSPVGLASSASLLAVRVWPSAEYTRITLEGSSRLRHSHMLVEDPQR
                     LVVDLEGVQLDSVLQSLPSKVLDSDPYIRLIRAGQNRPGVVRVVIELKAAINPQVFTL
                     DPVGSYGHRLVLDLHPTEAHDPLMALIMKDSPMDAAMGDAGGNTAAVAREEPREPVRR
                     GKRNEPAVDRLYTVVLDAGHGGEDPGAIGRGGSYEKDVTLSIAHRLKRKIDAMPGMRA
                     VLTRDGDYFVPLHQRVARARRVRADLFVSIHADAFVRPEANGSSVYVLSERGASSSAA
                     RWLAQKENDADLVGGVNLARQDGHIARTLLDLSQTATINDSFKLGRAMLGELGNINRL
                     HKPEVEQAGFAVLRAPDIPSVLVETAFISNPQEERRLNDEAYQDKMATALMRGVKRYF
                     EEHAPSAPTRVARLD"
     gene            complement(21817..22347)
                     /gene="tsaE"
                     /locus_tag="P5537_08740"
     CDS             complement(21817..22347)
                     /gene="tsaE"
                     /locus_tag="P5537_08740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HRV78166.1"
                     /translation="MIESIQTADDNGARLQAHLPDEAATVALGAAFARVLAPGLQIWL
                     QGNLGTGKTTLTRGLLRGLGHEGKVKSPTYTLIEPYVVSSLNLYHFDFYRFTSPDEYL
                     DAGLDEYFAGEGVCIVEWPDKASPHLPSPDVEIVLQAGGSGRDVAISANTEAGRTCVI
                     GLVKALRGADPAPGTT"
     gene            22363..23463
                     /gene="queG"
                     /locus_tag="P5537_08745"
     CDS             22363..23463
                     /gene="queG"
                     /locus_tag="P5537_08745"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HRV78167.1"
                     /translation="METKLPAPDGAAADGTILDGAALVARIRQWGRELGFDAVGVGGV
                     DLTDAEPGLAAWLEAGFHGDMDYMARHGMKRARAAELLPGSIRVISVRIGYWPDAAPA
                     LQVLADGERAYVSRYALGRDYHKLVRNRLQKLADRISAEVAHQYRVFTDSAPILEVEH
                     ASRKGLGWRGKHTLLLDRAAGSWFFLGEILTDLPLPVDAPVESHCGRCTACIDACPTG
                     AIVAPYQVDARRCISYLTIELHGAIPEELRPLLGNRIYGCDDCQLVCPWNRFAQLGRE
                     PDFAPRQGLDDARLAELFAWTAAEFAERTAGSPIHRIGHARWLRNIAVALGNGPATPA
                     ARAALHARADDEDAMVREHVAWALARLDAAAG"
     gene            23500..23700
                     /locus_tag="P5537_08750"
     CDS             23500..23700
                     /locus_tag="P5537_08750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SlyX family protein"
                     /protein_id="HRV78168.1"
                     /translation="MEERIVVLETKLMAAEDLLDELNRTVWRQQQELDLLRQHLHQLA
                     QQVKTLQPGDPLRPEDEIPPHW"
BASE COUNT         3700 a         7946 c         8573 g         3755 t
ORIGIN      
        1 tcggtgagat cgcagtagtc caggcagtcg cgaatggata gcatgccgtt tcctccaggt
       61 ccgggccgtc tgatgcggct ttgtcttcaa ttcaaggata gtggaccagt ccggttttac
      121 aagttcgata gaaattcaaa acaaagaaca agtcgttgat taagaaagcc gattttgcga
      181 tgtgcgtgct cgtgcggcgc accagcgcca tgtaatcagt cgcctgcgaa ggttttccga
      241 gaatccgcat caacttttgc cgatggtttt tcaggaacgt ttccgatgct cgatatccag
      301 cttctccgca cccagctcga ccacgtcgcc gctcgcctcg ccacgcgcgg gctgcagctc
      361 gacaccgccg ccttccaggc cctggaggac gagcgcaagc agttgcagac ccgcacccag
      421 gagctgcagg cccgccgcaa cgcgctctcc aagcagatcg gcatgctcaa gggcaagggc
      481 gaggacgcct ctggcgtgat ggccgaggtc gcccagctcg gcgacgagct caaggcctgc
      541 gagcaggccc tgccgacctt gctcgagcgc atgaacgcct tcctcgccac gctccccaac
      601 ctgccccagg aagacgtccc cgtgggcgcg gacgagagcg gcaacgtcga ggtgcggcgc
      661 tggggcacgc cgggcaccta cgacttcgag gtgcgcgatc acgtggacct gggcgcgccg
      721 ctcggcctcg acttcgagac cggcgccagg ctctcgggct cacgcttcgc cttcctgcgc
      781 ggcccggtgg cgcgcctgca tcgtgcgctg gcgcagttca tgctcgacac ccacacccgc
      841 gagcacggtt acaccgagtg ctacacgccc tacatcgtca acggctcggc gctctacggc
      901 accggccagc tgcccaagtt caaggaggac ctgttctggg tgctgcgcgg cggcgacgag
      961 gaggggctgg agcaatacct gatcccgacc gcggagatca cgctcaccaa cagcgtgcgc
     1021 gaggaggtgc tcgcgctcga ggccctgccg atccgcctca ccgcgcacag cccctgcttc
     1081 cgctccgagg ctggcagcgg tggtcgcgac gtgcgcggca tgatccgcca gcaccagttc
     1141 gacaaggtcg agatggtgca gatcgtcgag ccggcgaaga gcaacgaggc gctggagcag
     1201 atggtaggcc acgccgaggc catcctgcag aagctggagc tgccctaccg ggtgatcacc
     1261 ctatgcaccg gggacatggg cttcggtgcc gcgaagacct acgacctcga ggtctggctg
     1321 ccggcgcaga acacctaccg cgagatctcc agctgctcga actgcgagtc cttccaggcg
     1381 cgccgcatgc aggcccgctt caagaacgcg caaggcaaga acgagctggt gcacacgctc
     1441 aacggctcgg gtctcgccgt cgggcgcacg ctggtcgcgg tgctggagaa ccaccagcag
     1501 gccgacggct cgatcgtgat ccccaaggcc ctggtgccct acatgggtgg cgtcgagcgc
     1561 atcgaagcgc ccctctgagc ggcgcgttcg tgcgcaggcg cgggcccttc gcgcggcccg
     1621 cgccacgcct cagcccgccg cggcctcccg cggcgcgccc gccatccacg cgcgcaggct
     1681 ctccagcatc gacagcaggg cgggcacgaa gaacagcacc agcaccaccg agaagcccag
     1741 gccgaaggcg atcgacgccg ccatcgggat caggaactgg gcctgcagcg agcgctcgaa
     1801 cagcagcggc gtgagaccgc cgaccgtggt cagcgaggtc agcagcactg cgcgcaggcg
     1861 gccgcaggag gcgccgacca gggcctcctg caaggctgcc cccttgtgct gcagctcctt
     1921 gaacaggctc accaggatga tcgagttgtt caccacgatt ccggcgaggc cgaagaggcc
     1981 gaacatcgac aggatggtga ggtcgatgcc gagcagccag tggccgaaga tcgcgcccgc
     2041 cagcccgagc gggatcgccg acatcaccac cagcggccag ctccacgacg agaacgacca
     2101 caccagcacg aggtagatca ggcccaggcc gagcacgagg ccggccttca tgtccgccat
     2161 ggtctcgcgc tggtcggccg agcgcccctc gaagctgaac tcgaagccgt atttgtgcgc
     2221 aagttgcggc agggtgtcgc gctcgagctc ggcctgaacc acattggcgt tgctgacgtg
     2281 agagtccacc gctgccgaga cctccaccgc gagccggccc tgggcgtggc gcagggcctc
     2341 gaagccgcgt cgcgactccc agcttgcgac cgttgcgagc ggcacgaagc ggccgtccgg
     2401 caggctcacg ttgatgcgct cgaagacgtc gagccggctg cgctcctcgc gcggcagcat
     2461 caccctcacc tcgagctcgt cgcggccgac ctgcacgagc tgggcgagcg cgccgtcgaa
     2521 ggcggcgcgc agctggcggc ccaggctctc ggtggtgagc ccgagcgcct cgccggccgg
     2581 ggtcaggcga tagacgagct gctcgcggcc gtagggcatg tcgtcctcgg gctcgctgac
     2641 gccggggatg ctcttgaggg tctcggcaag ctcgagggcg gcggtcttga gcgcgtcggc
     2701 gtcgtcgccg gtgaggcgga tgttgatgtc gcgccccggt ggtcccgact ggcgtgcagt
     2761 aaaggtgagc agctccaggc ccgccaccgt cggcagcttc tcgcgccaaa ccgccaggaa
     2821 gcgctcgttg cgcacctcgc gggtgtcggg cgggacgagc tcgaccatga tgccggcgag
     2881 ctggtcgccg cgcgcgctgc tgccgctgcc gctgctgatg gtgccgccaa ggcgcgccac
     2941 cgccgtctgc accaggtcgc cgccgagttc cgcctccgcg gcgaacagcg cacgctcgag
     3001 ctcgccgagg aaggcctcgg tgtgcgcgcg tggcgtaccg gcgacgaagg tggcgttggc
     3061 gtagatcacc tgcccctcgg gggtggggaa gaacacgaag ccgatgcgcc cgcccgcgat
     3121 cagcccgacc gcgagcacca ttaggccgaa ggtgaaggcc accgtggcgc cgcgccaggc
     3181 gagcgcgcgc tccaccaggc ggcggaaggg gccgtcgcga aagcgcgcga agcccccgtc
     3241 gatgcgcgcg cgcagtgccg agtgctcgag cgccgcggcg ccggcgagcg cgccgcgcag
     3301 atgggcgggc aggatcagga agcactcgat cagcgaggcg gtgatcaccg ccaccatcac
     3361 gaaggggatg tcgccgagga tgttgccgat gatgccgccc accatcatca gcggcaggaa
     3421 ggccgccacc gtggtgagcg aggacgcgat caccggccac agcatgcggc gcgcgccccc
     3481 gagcgcggcc tgggctgcgc cttcacccat gtggcggtgg gtgtcggcgt cctcgctgac
     3541 cacgatggcg tcgtcgacga tgatgcccag cgccatgatc agcgcgaaca ggctcatcat
     3601 gttgagcgtg ccgccgagga cgtacatcag cgccagggtg gcgaggaagg cggtgggcac
     3661 gccgaccatg acccagaacg ccacccgccc cggcaggaag aagtacagca ccgcgactac
     3721 cagcaccagg ccggagaggc cgttgttcac cagcagctcg atacgctcgc tgatgagctg
     3781 ccactgctcg tcgaagacct ccagatggat gctcggcggc agcgtcgggc gggtcttctc
     3841 cagccagccc tcgagcacgc gtgcggcctt cagcgagtgg ccgctctcgc tgcgctgcaa
     3901 ctgcatctcg acgaccgcgt cgccgcgctc gaacagcgcc agctcgttgt tgcgcggctc
     3961 gcgggtgagg cgcgcgatct cgccgaggcg gaccaccccg agcgtgtcgc tcaccaccgg
     4021 cagcggcgcg aaggcgtctg cgctgcggcg ttgctcgagg ccgcggatct cgcgcgcgcc
     4081 gtcggcctcg ccggcgatgc cggcgggaaa gtcgcgtgcg agctggccga cgcggtcgcc
     4141 cacctgaacc agcgacagcc cgagcgtctc cagcgccgcc gcggggatct cgatcgcgat
     4201 gcgctcctcg ggcaggccgg tgagggtgat gcggtcgatg ccggcggcga gcagctcgct
     4261 ctcgaagcgg cgcacccagg ggcgcagctc ctcgatgctg ccgccgcgca cgagcaggcg
     4321 cgcgatgggc tcgtagcgcg acacccgact gacctccgga gtctcggcat cgcgcggcag
     4381 gttgcggaac tcatcgacgc gctggcgtac ctggtcgagc gcgagcaggg cgtcggtgtc
     4441 ctcatgcagc tcgagggtga tgctggcgac cccctgcgcc gaggtggagc tcatcttctt
     4501 gagcccgtcc accgtcttca agcgctcctc gagcggtgcg gtgatgccga tctccacgtc
     4561 ctcggccgag gcgccggtcc acaccacccg caccgagatc acgtcgagct cgaaggtggg
     4621 gaagaactgc acgttcatgc gcgtgatgcc gatcgtgccg agcacgaagg cgagcagcat
     4681 cagcacgttg gcggcgacct tgtgcccggc caggcgctcc agcaggctga cgtgcctcat
     4741 cgcgccgctc cggcggcttc gcctccggac ccctgggcgc cgaccaccgt gtcacccacc
     4801 acctcgaccg cgaggccgtc gatcgcgtgc ggcaggtggg tgcgcgagac cagcatgccc
     4861 tcgcgcagcg gcgcggcctc gtcacgggca cgaaccagca tcacgaggcg ctcgccgtcg
     4921 cggcgctcgc cggcacgtac caccggcact gccctcagac ggccgtcctc gacgcggtag
     4981 atgcggtcgc cgccgtgcag cgccgagggc ggtacgggga acacggcctc gagccgcggt
     5041 cgctccagca ccgcattgag gaaggcgccc accggcagcc tggcggcgtc gtccatgcgc
     5101 agcagcacgt ccacgccgcg cgcgtcggcc tcgccgccga tgcgctcgag gcgcgcgccg
     5161 agccggctgg tgccaaactc ggcgtgcgcg cgcaacgcct cgccacggct caaggcggag
     5221 cgcagctcct ccgcatagat cgccggcacg cgcgcgcgca ggaagagcgc gtccgaaggg
     5281 tagaggttca gcagcgcctg cccgggctgg acgtggtcgc ctgcggcgac ttcgaccttg
     5341 ccgatgcggg ctgcgaaggg cgcgacgacc tcgccgcgct ccgcgtcacg gcgggcctcc
     5401 gccaggcgca cctggagctg ggcgaggcgg gcggggtgct cggcgatcgc ctggcggcgc
     5461 tgggtgagcg aaagacgcac gcgcgcaacc tcctcacgcg cctggtcgaa ggcgctctcg
     5521 gcgccgaggc gggcgttctt gaggcgctcg aagcgggcaa gcttggcctc ggcaagctcg
     5581 agcagggtgc gctcctgcgc gatcgcctcc tggtcgtggc ggtggcggat gcgctcgcgc
     5641 tcgagctcgg ccgcggcctg gtcgacgcgc ggcttcaggt cgcgtggatc catgcgtgcg
     5701 agtaccgcgc cggcggcgac acggtcgccg tcgcgcaccg tcacttcgag cacgcgaccg
     5761 ccgaccggtg ccgcggcgcg cacgcggtcc ggcgcctcga tgcggccgta gagcaccagg
     5821 gtcgggtgca ccgcgatcgc ggcgagcggc tcggcctcga tccgccatac ccgctcgcgc
     5881 gcttccactg ccggcggggc gggacgggtg gcgcgcaggg cgaggaatcc ggtcgcggcc
     5941 agcacgagga tgaggacggg aagcagacga cgcatggggc agtgcctcgg gtgcccgggc
     6001 ggggcgggtt tatcaggaaa cgcttattgt attgcgggag ccgcgtcagc gctcgtccag
     6061 ccacaccgac tcccagcgcg cgagctcggg gaagtggtgt tcggcgcgtg cggcgagcgc
     6121 gcggtcgagt tcgtcgatga ggccgtgcag tgatggctcg ggcgtgtggg ggagctcggg
     6181 ctcgaactcg acgacgaggt cgccgcaggc gcgtcggcca tgcgccggga agcccgcgcc
     6241 gggcacgcgc aggctgcgcg gatgggcaag gccgggttcg agctcgatgt tgcgcacacc
     6301 ctccgggtgg ggcacgcgca gggtaccgcc gatcaacaga cgtagcgcgc tgaccgggcg
     6361 gcgcaacacg aggtcgcggc cctcgcggcg aaacagcgga tggctggcga ggcggatgcg
     6421 caggcgcagg tctccggcac gatgaagcgg gtcggaatgc ggctcaccct cgccggcgag
     6481 gcgcagctcg tcgtcatcca ccactccggg cgggacgcgc acctcgaggc gccgggtctg
     6541 cagttgctcg ccgctgccgt cacagccgcc acaggggccg gtgttgcgat agccgcgccc
     6601 ctcgcagtca ggacagcgct ccagaccggc gggaccgcgc actcggcccg agccgcggca
     6661 gggcgtgcac agccggctca cgctgagccg ctcgatgccg ctcccgccgc actgcgtaca
     6721 ggggctgcgg cgctcgacct cgaccgcgtg cagcgcgccg gcaaaactgt cctcgatgct
     6781 gatctccagc gtctgccagc ggtcggcgcc tcgttgcggc gcagcttcgg cggcggcctc
     6841 gtcctcgtgc ggggcctgcc cctcgtcgcc gagcagggtg gagagcaggc ggtcgtgcgc
     6901 atcgcgcagc cgcctgaact gctcggcggc ggcagggtcg gggttgcggt cgggatgcca
     6961 ttgcatggcg agcttgcgga aggcgcgctt gatctgctgc gcgctcgcgc cggctggcag
     7021 gccgagcagg gcatgggggt cggacatgga cggaaggctg tggactgcga gggcaacagc
     7081 ttaaccgagc ttgccggcgg atgtggcgca cgggcttgac caatccgtta aggctgcaag
     7141 aatgtcatgc cgtactcaat acggaatcgt atggtgcgcg atgccggcgg aactcgccgg
     7201 gacgcgaacg ggcatgagag aaaagacatg gagacgaagt gccgatgagc cgaccccgag
     7261 cttccgacat cccgccccgc gacttgtggg tggatcatcc gcagggccgc atcttcgcca
     7321 gggagtggaa tccgcccggg ggcgacgcgg tgggcgcagc gagtccgatc gtgctgttcc
     7381 acgactcgct cggttgcgtc gagctgtggc gcgactttcc tgcggcgctg agcgtggcga
     7441 gcgggcggcg ggtgatcgcg tacgaccgcc tcggtttcgg ccgctcggat gcgcgcgagg
     7501 cgcttcccga gctcgacttc atcgccgagg aggcacgggt ttatttcccc gcggtacggg
     7561 agcagctcgg cctggagcgc ttcgtggtgt tcggccacag cgtgggcggc ggcatggcgg
     7621 tgaattgcgc ggcggcgttt gccggcgctt gcgatgcctt gatcaccgag tcggcgcagg
     7681 tgtttcccga ggacctgacc ctgagcagca tcgccgcggc caaggggcag ttcgtagacg
     7741 aatcgcagct gcagcgcctc gcccgctatc acggcgacaa ggcgcgctgg gtgctggatg
     7801 cctggacgga gagctggctg catcccggct tcgccgcctg gtcgctgaag tcggtgctgc
     7861 cacaggtgcg ttgcccggtg ctggccatcc acggcatgca cgacgagtac ggcaccagcg
     7921 tgcatcccga gacgatcggc gagctctcgg ccggcccggc gcaggtcgcc atcctgccgg
     7981 acaccttcca cgtgccgcat cgcgagcgcc ccgaggcggt catcgagctc gtctgcgctt
     8041 tcctcgagcc ggtgcggcgg ggcaaggcgg cgtgtgcgtc gtgaccggat gcggcggcag
     8101 gggcggtgga ggagcggaaa gaggctccgc gaacgaaaaa acgccgaccc ggtgaggagt
     8161 cggcgtttcc tgaatctggc gcgcccggaa ggattcgaac ctcctacccc ctggttcgta
     8221 gccaggtact ctatccagat gagctacggg cgcgttgccg aaatcgttta gagcccgaca
     8281 tcggaaggct gtgtttggcg cgcccggaag gattcgaacc tcctaccccc tggttcgtag
     8341 ccaggtactc tatccagatg agctacgggc gctttttgct gcactgcgaa ggagcgggat
     8401 tataacgact gttcccacaa cttcaagttt tatttggcgg agagggtggg attcgaaccc
     8461 acggtaggct tgcacctacg cctgatttcg agtcaggtac attcgaccac tctgccacct
     8521 ctccgctcga aggtcggcat tatagtgttt tttttttgga agtgaactgt tttttgctgc
     8581 cggtcgaaac gcgacgccgc gtcctcggcg gtggcgccgg gcacgcgcgc gggcatggcc
     8641 gcaggcgcgg cagcgatgcg cccgttcact tggcctgcgg cagcatttcc tcgtaggcgc
     8701 gcaccgcttc cgccgcgtac atcagggccg ggccgccgcc catgtaggtg cacacgccca
     8761 gggtctccat gatctgctcg cgagtggcgc cgaggcggat cagcgccttg atgtggaagc
     8821 cgatgcaggc gtcgcagcgt tgcgatactg cgatcgcgag cgcgatgagc tccttctgca
     8881 gctcgctcag cgcaccgtcc tgcagcgagc tcttggccat cgcgccgaag ccgtgcatgg
     8941 tctcggggat ttccttgcgc aaggtggcga gggccttgga gacgtcgccg atgagctgga
     9001 cgtgggactt ggacatgatg cgttctccta tttcagaaaa cgcttatctt actccgccgc
     9061 tgcgctcgcg gctattgcat tgcagcatcg cgcgcccgat ccatcccgcg ccggcgctcg
     9121 agcgcgggct gtgcggtgag ccgctcaggc gtcgcggcgc ttgtcgcgct cgatcagcgc
     9181 gtaggcggag tggttatgga tggactcgaa gttctcggat tcgaccacgt aggcgtcgat
     9241 gcgcggctcg cggttcagct ccccggcgac gtcgcgtacc atgtcctcga cgaacttggg
     9301 gttgtcgtag gcacgctcgg tcacccactt ctcgtcgggg cgcttgagca ggccgaagac
     9361 ctcgcacgaa gcctgcccct cgaccatctg caccatctcc tcgatccaca ggtggtcgtt
     9421 gagcaccgcg gtgacggtga cgtgcgagcg ctggttgtgc gcgccatagg ccgagatctt
     9481 cttcgagcat gggcacaggc tggtcaccgg aacgaccacc ttcatggtga attcgtacac
     9541 gccgccctcg cggatgctgc cgatgaagca gacctcgtag tccatcaggc tctgcacgcc
     9601 ggataccggg gcggtcttgt tgatgaaata ggggaagctc atctcgacgt ggccggtctc
     9661 ggcctccagg cgttcgacca tggtgcgcag catgggctcg aagttctcca ccgagatctc
     9721 gcgctcgcga ccgttgagga tctcgatgaa gcgcgacatg tgggtgccct tgaagttgtg
     9781 gggcaggccg acgtacatgt tgaagctggc caccgtgtgc tgcacgccgc cgcgcttgtc
     9841 ggcgaccttg atcgggtggc ggatcgactt gatgccgacc ttgtcgatcg cgatccggcg
     9901 gctgtcggcg ctgctctgca cgtcggggat ggcgattgcg gtgggggcgt tcatgggcag
     9961 gttccctgca gatggtcggg ggatgggcgc gccggaaccg gcagcgaagt gcaattgtgt
    10021 tgcacttcgc tgccgatctt aactttcccg acaaaaatgc tcaagcttta ggcgcagccc
    10081 cggttgcgcg ctcgatgctg gcgaggatgc cggcccggtc cagtccgacc gaggcgagca
    10141 gctgcccctg gtcgccgtgg tcgatgaagt ggtcggggag gccgaggcgc agcacgcgcg
    10201 ggcgcgcggc gaggctgtcg aggacgcgcg cgacctcggc tccggcgccg ccgatcaccg
    10261 cgctttcctc cagggtcacg atgagctcgt ggctggcggc gagctcggcg accagctcgg
    10321 cgtcgagcgg cttgacgaag cgcatgttgg ccacggtggc atcgagcgtc tcggcgactt
    10381 cgcgcgccac cccaagcagg ctgccgaagg cgagcagggc gatgccgcgg ccgtggcgca
    10441 cgacctcccc cttgccgatc ggcagggcgc gcatctgcgc ctgcggcacg gtaccgttgc
    10501 caccaccgcg cgggtagcgc accgcgctcg ggccggggtg ctgcaccgcg gtgtagagca
    10561 tctggcggca ctcgtcctcg tcggtgggcg ccatcaccac caggttgggg acacaggcca
    10621 ggaaggagag gtcgaaggcg ccgtggtggg tcgcgccgtc ggcgcccacc aggccgccgc
    10681 ggtcgatcgc gaacacgacc ggaaggttct gcagcgcgac gtcgtggatg agctggtcgt
    10741 aggcgcgctg caggaaggtc gagtagatcg ccaccaccgg cacgaagcct tcgcaggcca
    10801 ggcctgcggc gaaggtcacc gcgtgctgct cggcgatgcc gacgtcgaag taacgctcgg
    10861 ggaactcctg cgcgaagcgc accaggccgg agccctcgcg cattgccggg gtgatgccga
    10921 cgatgcgtgg gtcggccttg gccatgtcgc acagccagtc gccgaacacc tgggtgtagg
    10981 tgagcttgcc accgctcttg ccggcctgga tgccggcggt gtgatcgaac ttggagacgc
    11041 cgtggtagag caccgggtcg gcctcggcga gcttgtagcc ctggcccttg cgggtgatca
    11101 cgtggaggaa ctgcggcccc ttgagcttgc ggaggttctg cagcgtgggg atgagcgcgt
    11161 cgaggtcgtg gccgtcgatc gggccgtagt aatgaaagcc gaactcctcg aacagcgtgc
    11221 ctggcccgat catgcccttg gcgtactcct cgaccttgcg cgcgagttcg gccactggcg
    11281 gcgccacgcc cagcaccttc tcgccgacac ggcgcgcggt gttgtaggtc gagcccgaca
    11341 tcatgcgggc gaggatcttg gtgagcgccc cgaccggtgg cgagatcgac atctcgttgt
    11401 cgttgaggat caccagcagg ttgaggttct ccatgtcgcc ggcgttgttg agagcctcga
    11461 aggccatgcc ggcggacatc gcgccgtcac cgatcaccgc gatcgcgtgg cggtcctcgg
    11521 cacgcgcgcg cgccgcgacc gccatgccga gcgccgctga gatcgaggtg gaggagtgcg
    11581 cggtgccgaa ggtgtcgtac tcgctctcgc tgcggcgcgg aaaaccggag atgccgccga
    11641 agtggcgcag tccgctcatc gcctcgcggc ggccggtgag caccttgtgg ccgtaggtct
    11701 ggtggccgac gtcccacacg atgcggtcgt acggggtgtt gaagacgtgg tgcagcgcga
    11761 tcgtcagctc taccgtgccg aggttggagg acaggtggcc gccggtcttc gataccgact
    11821 cgatcaggaa ggcgcgcaat tccgtggcga gggcgccgag ttcgcggcga tcgagtgcac
    11881 gcacatcggc ggggcagccg atgcgttcca ggttcgggta gggggccatg gggggatccg
    11941 gctttcgggt tgttcttggg ggccgtcgtc gggcgtgatc agaaggcgcg gtgcacgatg
    12001 tagtccgcca gctgctccag gcgcagcgcg cgcgcgccga aggggcgcag gctggcgcgc
    12061 gcgtcatcga gcatctcctc ggcgagccgg cgcgcgtcga cgaggccgag caggctcaca
    12121 taggtcggct tgtcgttgtc ggcgtccttg ccggcggtct tgcccagcgt cgcggtgtct
    12181 gcctcggcgt cgaggaggtc gtcgaccacc tggaagagca ggccgacgac cttggcgtag
    12241 tggtccaggc gctcgagctc gccggcatcc agcgccgcgc cggcgcgtgc gccgagcagc
    12301 accgccgcgc ggatcagcgc gccggtcttg tggatgtgca tgaactccag ctcttcgcgc
    12361 cccagccgct tgcccaccgc agcgaggtcg atcgcctggc cgccggccat gccgcgcgag
    12421 ccggaggcga cggcgagctg gttcagcatc gcgagctggt tcgccggctc ggtgccgagc
    12481 ggacgctcgg cgagaacctg gaaggccagc gtctgcagcg cgtcgcccgc gagcagggcg
    12541 gtggcctcgt cgaactcgac atgcacggtg ggtttaccgc ggcgcagcac gtcatcgtcc
    12601 atgcacggaa ggtcgtcgtg caccagcgaa taggcgtgga tcagctcgac cgcgcaggcg
    12661 atgcggtcga ggtcctcggc cgcggcaccg gcgagtgcgc cggccgcatg cgcgagcagc
    12721 gggcgcacgc gcttgccgcc accgagcacc gcatagcgca tcgcctcgtg caggcgctgc
    12781 ggagccaccg cggggtcggg cagcacgccg gcgagcgcga cctcggtgcg ctgctggatc
    12841 tgagccgtcc attcggagaa ggaggggagc ttgctgtctg cgttcatgcg cctgcctggt
    12901 cgccgtcacg gctcgaatcg gtcgggaaat cggtgaggcc gtcgccttcg agcatgcgca
    12961 cgcgctgctc ggcgtcgccg agcgtggcct ggcagtggcg cagcaggccg acgccgcgct
    13021 ggtagcgcgc gagggcatcc tcgagcggta gattgccgga ttccatttcc tggacgatgg
    13081 cctcgagctc ggagaccgcc gcttcgaacg acttggggga ggatgccgac tttggcatgg
    13141 atcaatatct ggcgcggcaa aagcgggaaa ataaccgaag gcgggtatgg cggtcaaaca
    13201 ggggctgcct tacactaaac cctttatttt tccggatttc ttgtccgcaa gaggaggttc
    13261 ggggatgtcc gacatcgctt ccaaggctca actggcccag gctgcctccc agctgcctgt
    13321 ctcgtggtac ttcgaccaga aggttttcga actggagaaa aagctcctct tcgatgccgg
    13381 gccggggtac gtcggccatg agctgatggt tcccgaggtc ggcaactacc gttcgctcga
    13441 gtggctggac cattccaagc tgctgttccg caccgaggcg ggcgtccatc agatgtccaa
    13501 cgtctgccgc catcgccagg ccatcatgct gcagggcagc ggcaccacca agcacgtggt
    13561 gtgcccggtg caccggtgga cctacgaccg ccagggcaat ctgctcggtg cgccgcactt
    13621 tcccgagaag ccctgcctgg gcctcaggcg cgacgagctc gagcgctgga acggcctgct
    13681 cttcaagggg ccgcgctcgg ccggcgccga cctcgccggc atgcaggtgg cgggcgagct
    13741 cgacttctcg ggctacaagc tcgacaaggt cgagatccac cactgcaact acaactggaa
    13801 gaccttcatc gaggtctatc tggaggacta tcacgtcgtt cccttccacc ccggattggg
    13861 caacttcgtg acctgcaagg acctgacctg gcaattcggc gactggtatt cggtgcagaa
    13921 ggtgggtatc acctcgctcg ccaagccggg ctcggcgacc tacgccaagt ggcacaaggc
    13981 cgtgctcgac tactacggcg agaagaggcc cacgcacggt gcgatctggc tgacctacta
    14041 ccccaacatc atggtcgagt ggtacccgca cgtgctggtg gtgagcacgc tgatcccgac
    14101 cgatatcgac aggacgacca acgtggtcga gttctactac cccgaggaca tcgccgagtt
    14161 cgagcgcgag ttcgtcgacg ccgagcaggc cgcctacatg gagacggcga tcgaggatga
    14221 cgagatcggc gagcgcatgg accgcgggcg cagggcgctg atgaaggaag ggcgcaacga
    14281 ggtcggcccc taccagtcgc ccttcgagga cggcatgcag cacttccacg agttctaccg
    14341 ccgcatcatg gagcctcaca tcggcgggtg aggcgaagcg gctgcgttcg cgccttcctg
    14401 ccctcctaca gaaccgcttg cgtttggggt gggatgtagg agcggcggaa gtcgcgaatc
    14461 cggtcgtcgc gaggtgggcg cacgcctcag cgcgcgtcct gcagttcctt cggcagcgcg
    14521 aaggtcacgc gctcgggcac gccgtcgagg ttgcgcacct tgccgccgct caactcttcc
    14581 aggcgggcga tcacctctgc aaccagcacc tccggcgccg acgcgcccgc ggtgacgccg
    14641 acgcggcgct tgccctcgat ccaggcgggg tcgatgccgt cggcgttgtc gatcaggtag
    14701 gcgggcacgc cgcgcagttc ggcgacctcg cgcaggcggt tggagttgga gctgttcttg
    14761 gagccgacca cgaacaccac gtcggcgtgc ggggtcatga acttcaccgc gtcctggcgg
    14821 ttctgcgtgg cgtagcagat gtcgtccttc ttcggcccga cgatgcgggg gaagcgggca
    14881 cgcagcgcgt ccacgatcgc cgccgcgtca tccaccgaca gcgtggtctg ggtcacgtag
    14941 gcgagctgat cggggtcgga aacctgcagt gcggcgacgt cggccggggt ctcgaccaga
    15001 tggatgccgc catcgacctg gcccatggtg ccctcgacct cggggtggcc cttgtggccg
    15061 atcatgacga tctccttgcc ctggtcgcgc atccgcgcca cctcgacatg gaccttggtg
    15121 accagtgggc aggtggcatc gaacacgcgc aggccgcggc gctcggcttc ctcgcgcacc
    15181 gccagcgaga cgccgtgggc ggaaaagatc accgtgttgc cggcgggcac ctcgtcgagc
    15241 tcgtcgacga agatcgcgcc cttggcgcgc aggtcgtcga cgacgaactt gttgtgcacg
    15301 acctcgtggc gcacgtagat cggcgcgccg tagcgcttga gtgcgcgctc cacgatttcg
    15361 atcgcacgct cgacgccggc gcagaagccg cgcggattgg cgagcaggat ttccttatcg
    15421 ttcatctttt ttctctgtgg ggtgttgcgg gtggcgttca ggagatcccg atcacctgca
    15481 cctcgaagcg gatcgccttg cccgccagcg ggtggttgaa gtcgatcagc gccgactcgg
    15541 cgtcgatctc gcgcaccagg ccggagtagc gcgagccgtc gggggcggtg aactccatga
    15601 tgctcatggc ttcgatctct tcttcgggca tgtgttcgcg cttcacgcgc tcgacgagtt
    15661 cgtcgcgata ggggccgaag gcttcgtcgg cggcgagctc gaagacatgg tgggtgccgg
    15721 gcatgaggcc gatcagcagg cgctccatgg cgggcagcat ttcgcccgcg ccgagctgca
    15781 gcgtggccgg agtggcgttg aaggtgctga tcagcggctg tccgctcggc agcgagatgc
    15841 ggtagtgcag ggtgacgagg ctgttggcct ggatcgcttc gctcaagatg gtgctccggg
    15901 tcggggctgg tcgcctgtgg aggggccgaa aagctggccc cacagcatca tcacgacgcc
    15961 cacggtgatg gccgagtcgg ccaggttgaa cgccggccag ctccagccgg cgtagtggaa
    16021 gtgcaggaag tccacgaccg cgccgtgcac gatgcggtcg tagacgttgc cgagcgcgcc
    16081 gccgatgatc agcgcgaagg ccgccggcag cagcttctca tggcggtggt ggtgcatcag
    16141 cgcgagcagc caggcgctga tggcgagcgc cagcacggtg aagaaccagc gttgccagcc
    16201 gctgtgctcg gcgaggaagc tgaacgccgc gccggtgttg tacaccagca ccaggtcgaa
    16261 gaaacccgtc accgggatca tctcgccgcg gtgcaggttc gccagcacga gctgcttggt
    16321 gacctggtcg agcacgccga ccagcacggc gagcaccagc cacggcagca tcagcgcgag
    16381 cgcattgcgc ggcgcaggag agctcatcgt cgcggctgcc tcaggcatgg gtgcgggttt
    16441 cgcctgcgcc gaacaggttg ctcgcgcaac gtccgcacag cgtcggatgc tcggcatcgc
    16501 tgccgaccga atcgacgtag tgccagcagc gctcgcactt ctgcgccgag ctcggggtgg
    16561 cgacgatacg ctcgtgctcc gcgccggcca cttcggacag gatggccacc gaggtcatgg
    16621 tgacgaagcg caggtcctcg cccaggctga ccatggcggc gaacttgtcg gtggtgagcg
    16681 cgagctcgag ttcggcctgc agcgaggcgc cgaccttgcc ttcggtgcgc agcgcctcga
    16741 tgaccttgag gccctcggcg cgcaccgcgc ggatggtctc ccagcgcgcg atcaggccgg
    16801 cctcgccctc ctgagcgggc agggcgtgga aggtgtgcag catcacgctg tcggcttcct
    16861 cgccggcctt ggccgggttg aggatggccc aggcctcctc ggcggtgaag gacaggatcg
    16921 gcgccatcag cttcaacagg gtctgcgtga tgtgccacag cgcggtctgc gcggcgcggc
    16981 gcggcaggct gccggcggcg gtggtgtaca ggcggtcctt gaggatgtcg agatagaagg
    17041 cgccgaggtc ttcggcacag aacacctgca gcgcctgcac gatgcggtgg aactccatcc
    17101 tggcgtagtc ggcctcggcc tgctgcgcca tctggcgggt gaaggcgagc gcgtagcggt
    17161 cgaggtccat ccactgctcg agcggcacgg cgtccctggc gatgtcgaag tcggcggtgt
    17221 tggcgagcag gaagcgcagg gtgttgcgca cgcggcgata gacctcgacc acgcggtcga
    17281 ggatctcctt ggagatcgac agttcgcccg agtaatcggt ggacgccacc cacaggcgca
    17341 ggatctcggc gccgagcttg ccggtgactt cctgcggcac gaccacgttg ccgagcgact
    17401 tgctcatctt gcggccctgg ccgtccaccg cgaagccgtg ggtgagcagg ctgcggtagg
    17461 gcgcgtgccc gtcgatcgcg cagccggtga gcagcgagga gtggaaccag ccgcggtgct
    17521 ggtccgagcc ttccaggtac atgtcggcgc gcgggccttc cgggtgcccg tcgttgtgcg
    17581 agccgcgcag cacgtgcttg tgcgtggtgc cggagtcgaa ccagacgtcg agggtgtcgc
    17641 tgatcttctc gaactgcgca gcctcggcgc cgagcagctc ggcagcatcg agcttgaacc
    17701 aggcctcgat gccttcctgc tccacgcgca gtgcgaccgc ttccatcagc tcgaccgtgc
    17761 gcggatgcag ctcgccggtc tccttgtgca ggaagaaggg gatcggcacg ccccagttgc
    17821 gctggcgcga gatgcaccag tcggggcggt tggcgatcat cgcgtgcagg cgcgcctggc
    17881 cccaacccgg gtagaacttg gtcgcctcga ccgcgcgcag cgcgcgctcg cgcagcgtcg
    17941 agccgtcggc ggcgtcgcgg tccatgccga cgaaccactg cgcggtggcg cgatagacca
    18001 gcggcgtctt gtggcgccag cagtgcatgt agctgtgggt gatcttgccg tgcgacagca
    18061 acgcgccgac ttcggcgagc ttgtcgacga tgaccgggtt ggccttccag atgttcatgc
    18121 cgccgaagaa gggcaggtcg ggcacgtact cgccgccgcc catcaccagc gacaggatct
    18181 cctcgttgct gcggccgtag gcgcgccacg agttgaagtc gtccacgccg tgcgccggcg
    18241 ccgagtgcac gatgccggtg ccggcgtcga tgccgacgta gtcggccaga tacaccggcg
    18301 agacgcggtc gaagaagggg tgacggaact cgatgcggtc gagcgctgcg cccttggcgg
    18361 tggcgacgat cgtgccctcg cgctggtagc gctgcagggc ggattcgacg agctctttcg
    18421 cgagcaccag caggcgatcg ccgacgtcca cgagcgcgta gtcgaactcg gggtgggcgt
    18481 tgagtgcctg gttggcgggg atggtccacg gggtggtggt ccagatcacc gcggcggcgg
    18541 gcttgtcgag cttcgccagg ccgaaggcgg cggcgagctt gtcggcgtgt gccgcggaaa
    18601 ccggaaacgc gacgtcgatg gtcggcgagg gcttgtcggc gtactccacc tcggcctcgg
    18661 cgagcgccga gccacagtcg aagcaccagt tcaccggctt caggcccttg aacacgtagc
    18721 cgttcttcgt catctcggcg agcgcgcgga tctcgttggc ctcgttggcg aagtccatcg
    18781 tgcggtaggg gttgtcccag tcaccgagca cgccgaggcg gatgaagtcg gccttctgga
    18841 tctcgatctg ttcggcggcg taggcgcggc agagctcgcg caccttgtcc gcgggcaggt
    18901 tcttgccgtg ggtgacctcg accttgtgct cgatcggcag gccgtggcag tcccagcccg
    18961 gcacgtaggg cgcgtcgaag ccggcgagcg tcttcgagcg cacgatgatg tccttgagga
    19021 tcttgttgag cgcgtggccg atgtgcaggc tgccgttggc gtagggcggg ccgtcgtgga
    19081 gcacgaactt gggccggccg gcgctggcct tccggatgcg ctggtagagc ttgcgttgct
    19141 gccagtcggc gatccagccc ggctcgcgct tgggcaggtc gccgcgcatc gggaaggggg
    19201 tgtcgggcag gttgagcgtc ttgcggtagt cggccatggc ggagtcggaa gtcggtggga
    19261 tcgtcggggt tcgtcgggcc ttcaggcggg cagagggttc gcggccagcc agtcgcgggc
    19321 ggccaggctg tcgagcgcga tctgcgcacg cagcgcgtcg agcgaggaga atttctgctc
    19381 tgcgcgcagg cggtgcagga aatgtacgcg gatgtgggcg ccgtagcagt cctgcgccca
    19441 gtcgaagagg tggacctcga ggcgggcgcg gccgttcgcg gtcgcggtcg ggcgcagccc
    19501 gatgttggcg acgccggcca ccgggccggc cgcgaggccc tcgacgctca ccacgtacac
    19561 accgcccagc gccgggcggc ggtgcttcat ctggatgttc gcggtcggga agccgagctg
    19621 gcggccgagc ttgtctccat ggctgacccg gccagcgatg ctgtaggggc ggccgagcag
    19681 gtgcgcagcg tgggcgagat cgcctgcggc gagcgcggcg cgcaccgccg aactcgacac
    19741 gcgctcgccg gcgaccgtga gcgtgggcat ggactccacc ccgaagccca gccgtgcgcc
    19801 ggcttcctgc aacattgcga agttgccctg gcggcgggcg ccgaaacgga agtcgtcacc
    19861 gatgaagagg tgacgcacgc cgaggccgcg caccaggatg tcgtcgatga aagactgcgc
    19921 gggttgtgca gcgaagcgcg catcgaagcg gcagacgtgg cagcggtcga cgcccgcggc
    19981 agacagcagc agcagcttct cgcgcagcga ggcgaggcgg gcgggagcat cggcgggact
    20041 gaagtattcg cgcgggtgcg gctcgaaggt gagcaccacc gccggcaggc cgagcgcacg
    20101 ggcctttccg gtgagcagcg agagcagcgc ctggtggccg agatgcacgc catcgaagtt
    20161 gccgatggtg agcaccgcag ccgtgtcggc gtgctcggga atcccgcggt gaacctgcat
    20221 aagcgcctga aaaagccgcg attatagcgg caaaggccag tgctgcgggc ctcggaggca
    20281 gagccggaca cgcggacgag ggtggcgagc agccgctcgc cgagtgccgg accgccccgt
    20341 tcgccgctgc acggccatcg aagccggggg ggcatgtagg agcgccggca ggcgcgaaag
    20401 cggcgctccg ccaaccgatc acgccaccgc tccggcacga gtctcggcaa gcctgccgga
    20461 cgcgaaggcg atacgccgct cagtcgagcc gcgccaccct ggtcggggcg ctcggggcgt
    20521 gctcctcgaa gtagcgcttg acgccgcgca tcagcgccgt agccatcttg tcctggtagg
    20581 cctcgtcgtt gagccggcgc tcttcctgcg gattgctgat gaaggccgtc tcgaccagca
    20641 ccgagggaat gtcgggtgcg cgcagcacgg cgaagccggc ctgttcgacc tcgggcttgt
    20701 gcagccggtt gatgttgccg agctcgccga gcatggcgcg cccgagcttg aagctgtcgt
    20761 tgatcgtcgc ggtctgcgac aggtcgagca gggtgcgggc gatgtggccg tcctggcggg
    20821 cgaggttgac gccgcccacg aggtcggcat cgttctcctt ctgcgccagc cagcgcgcgg
    20881 ccgaactcga ggcgccgcgc tcggagagca cgtacaccga gctgccgttg gcctcggggc
    20941 gcacgaaggc gtcggcgtgg atggacacga agaggtcggc acggacccgg cgggcgcggg
    21001 ccacgcgctg gtgcaggggc acgaaatagt cgccgtcccg cgtcagcacc gcgcgcatgc
    21061 ccggcatggc gtcgatcttg cgcttgaggc ggtgcgcgat cgacagggtg acgtccttct
    21121 cgtagctacc gccgcgtccg atcgcgcccg ggtcctcgcc gccatggccg gcgtcgagca
    21181 ccacggtgta caggcgatcg accgccggtt cgttgcgctt gccacgccgg accggttcgc
    21241 gcggctcctc gcgcgccacc gcggcggtgt tgccgccagc gtcgcccatg gccgcatcca
    21301 tcggcgaatc cttcatgatc agcgccatca gcggatcgtg ggcctcggtc gggtgcaggt
    21361 cgagcaccag gcggtggccg tagctgccca ccgggtccag ggtgaacacc tgcgggttga
    21421 tcgcggcctt gagctcgatc accacgcgca ccacgcccgg ccggttctgc ccggcgcgga
    21481 tcaggcggat gtaggggtcg gagtcgagca ccttggaggg cagggactgc agcacgctgt
    21541 cgagctgcac gccctcgagg tcgaccacca ggcgctgcgg atcctcgacc agcatgtggc
    21601 tgtggcgcag gcgggatgaa ccctctaggg tgatgcgggt gtattccgcc gacggccaca
    21661 cgcgcaccgc gagcaggctc gccgaacttg ccagcccgac cgggctcacc agcatggcca
    21721 gtgacgcgcc ggccagcttg agcagccggc ggcgatcgat acgccccgcg gcgaaggcct
    21781 cggcagcgct ggcgagcccc gaggcctggg agaggctcag gtcgtcccgg gcgccgggtc
    21841 cgcgccccgt aaagctttca ccagtccgat cacgcatgtt cgccccgctt ccgtgtttgc
    21901 gctgatcgcc acatcccgcc cggatccgcc ggcctgcagg acgatttcga cgtcgggaga
    21961 gggcagatgg ggcgaggcct tgtccggcca ttccacgatg cagacgccct caccggcgaa
    22021 gtattcgtcc agccccgcgt cgagatattc gtctggcgag gtgaagcgat aaaaatcaaa
    22081 gtgatataag tttaagctag aaacgacgta aggttcaatc aaggtgtagg tcgggctctt
    22141 caccttgccc tcgtggccga gcccgcgcag caggccgcgg gtgagggtgg tcttgccggt
    22201 gccgaggttg ccctgcagcc agatctgcag cccgggggcg agaacgcggg cgaacgcggc
    22261 gccaagcgcc acggtggcgg cctcgtcggg caaatgcgcc tgcaggcgtg cgccgttatc
    22321 atcggcagtc tggatcgact cgatcatcgg gacctctgac aaatggaaac aaaattgccg
    22381 gcgccggacg gggcggcggc cgacgggacc atcctcgacg gcgcggcgct tgttgcgcgg
    22441 atcagacagt gggggcgcga actcggcttc gacgcggtcg gcgtcggcgg ggtcgatctc
    22501 accgatgccg agcctggcct ggccgcctgg ctggaagccg ggtttcacgg ggacatggat
    22561 tatatggcgc gccacggcat gaaacgcgcg cgcgccgccg aactgctgcc cggcagcatc
    22621 cgcgtgatca gcgtacgcat cgggtactgg cccgatgccg cgccggcgct gcaggtgctc
    22681 gccgatggcg agcgcgccta cgtgtcgcgc tacgcgctcg gccgggacta ccacaagctg
    22741 gtgcgcaacc gcctgcagaa gctggccgac cgcatcagcg ccgaggtcgc gcaccagtac
    22801 cgcgtgttca cagactcggc gcccatcctc gaggtcgagc atgccagccg caagggcctg
    22861 ggctggcgcg gcaagcacac cctgctgctc gatcgcgccg cgggctcgtg gttcttcctc
    22921 ggcgagatcc tcaccgacct gccgctgccg gtggacgcgc cggtggagtc gcactgcggg
    22981 cgctgcacgg cctgcatcga cgcctgcccc accggcgcca tcgtcgcgcc ctaccaggtc
    23041 gacgcacggc gctgcatctc ctacctcacc atcgagttgc acggcgcgat ccccgaggag
    23101 ctgcgcccgc tgctcggcaa ccgcatctac ggctgcgacg actgccagct cgtgtgcccg
    23161 tggaaccgct tcgcccagct cggtcgcgag cccgatttcg ccccccgcca ggggctggac
    23221 gacgccaggc tggccgagct gttcgcgtgg acggcggccg agttcgcaga gcgcaccgcc
    23281 ggcagcccga tccaccgcat cggccacgcg cgctggctgc gcaacatcgc ggtcgcgctc
    23341 ggcaacggcc cggccacgcc ggcggcgcgc gcggccttgc atgcgcgcgc cgacgacgag
    23401 gatgcgatgg tgcgcgagca cgtcgcctgg gcgctcgccc gccttgacgc cgccgccggc
    23461 tagaatgcgc gcccgcaacg agaatcagga ccacccgcca tggaagagcg catcgtcgtg
    23521 ctggagacca agctgatggc tgccgaggac ctcctcgacg aactcaaccg cacggtctgg
    23581 cgccagcagc aggagctcga cctgctgcgc cagcacctcc atcagctcgc ccagcaggtc
    23641 aagaccctgc agcctggcga cccgctgcgc ccggaagacg agatcccgcc gcactggtga
    23701 gcgcagccgg cacaaacgaa ccacgcccat gcaggagcgc ctgcaggcgc gaatgcggcg
    23761 gtggaacgtg cgccgcgccc gtcggagccg cggtctggtt catgtaggag cgccggcagg
    23821 cgcgaaagcg gcgcgtgaga aatagacgcc ggcgggtacg cccacggctg gattcgcgcc
    23881 tgccggcgct cctacaaccc gccgggccgt ggcgccatcc ctgcggctgc tttcgctgca
    23941 ccgggcggtg aattgagggg cgaggccgtc gcaa
//
LOCUS       DAOTIN010000046        23423 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_2554_length_23423_cov_10.137496, whole genome shotgun
            sequence.
ACCESSION   DAOTIN010000046 DAOTIN010000000
VERSION     DAOTIN010000046.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 23423)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 23423)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23423
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2554_length_23423_cov_10.137496"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1158
                     /gene="tuf"
                     /locus_tag="P5537_08755"
     CDS             <1..1158
                     /gene="tuf"
                     /locus_tag="P5537_08755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012081251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HRV78169.1"
                     /translation="HVNVGTIGHVDHGKTTLTAAITTILSKKFGGEAKAYDQIDAAPE
                     EKARGITINTAHVEYETATRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPM
                     PQTREHILLARQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSKYDFPGDDIPIV
                     KGSALKALEGDQSDIGEPAIFRLADALDSYIPTPERAIDKPFLLPIEDVFSISGRGTV
                     VTGRVERGIVKVGEEIEIVGIKPTVKTTCTGVEMFRKLLDQGQAGDNVGVLLRGTKRE
                     DVERGQVLCKPGSITPHTHFTGEIYVLSKEEGGRHTPFFNNYRPQFYFRTTDVTGSIS
                     LPEGTEMVMPGDNVSITVKLIAPIAMEEGLRFAIREGGRTVGAGVVAKIIE"
     gene            1246..1557
                     /gene="rpsJ"
                     /locus_tag="P5537_08760"
     CDS             1246..1557
                     /gene="rpsJ"
                     /locus_tag="P5537_08760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014235480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HRV78170.1"
                     /translation="MQNQKIRIRLKAFDYRLIDQSALEIVDTAKRTGAVVRGPVPLPT
                     RIERFDLLRSPHVNKASRDQMEIRTHQRLMDIIDPTDKTVDALMKLDLPAGVDVEIKL
                     Q"
     gene            1670..2308
                     /gene="rplC"
                     /locus_tag="P5537_08765"
     CDS             1670..2308
                     /gene="rplC"
                     /locus_tag="P5537_08765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HRV78171.1"
                     /translation="MSLGLVGRKVGMTRIFAEDGKTIPVTVLDVSDNRVSQIKTIDTD
                     GYAAVQIAYGKRRASRITKPVAGHLAKAGVEPCRGIKEFRVEAEQAGGMNAGDAIGAD
                     LFQVGQKVDVTGVTIGKGFSGPIKRHNFSSNRASHGNSISHNSPGSIGMAQDPGRVFP
                     GKRMAGQYGNVQRTTQGLEIVRVDVERQLLLVKGAVPGAKGGDVVVRPAVKA"
     gene            2319..2939
                     /gene="rplD"
                     /locus_tag="P5537_08770"
     CDS             2319..2939
                     /gene="rplD"
                     /locus_tag="P5537_08770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011767139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HRV78172.1"
                     /translation="MELKLLNDQGQAASTLEASDVLFGRDYNEALVHQVVTAYLANAR
                     SGNRKQKGRSEIAKSTRKPFRQKGTGNARAGMASSPLWRGGGKIFPNTPDENFSQKVN
                     RKMYRAGVAAILSQLAREDRLAVVENFSVEAPKTRLLSQKLKGMGLDSVLVITDEIDE
                     NLFLSSRNLHQVLVLEVNEADPVSLVRFPKVLVTKGALAKMEEAWQ"
     gene            2936..3241
                     /gene="rplW"
                     /locus_tag="P5537_08775"
     CDS             2936..3241
                     /gene="rplW"
                     /locus_tag="P5537_08775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002931584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HRV78173.1"
                     /translation="MSAISQERLLQVLLAPQISEKATFVADKNEQVVFKVASDATKPE
                     VKAAVESLFKVEVKSVQILNVKGKAKRFGKTMGRRKDWKKAFVCLKPGQEINFAAGE"
     gene            3248..4075
                     /gene="rplB"
                     /locus_tag="P5537_08780"
     CDS             3248..4075
                     /gene="rplB"
                     /locus_tag="P5537_08780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HRV78174.1"
                     /translation="MAIVKLKPTSAGRRAQVKVVNPDLYKGRPVDALIEKQTKNAGRN
                     NYGRVTMRHQGGGHKQHYRLVDFRRNKDGIPAKVERIEYDPNRSAHIALLCYADGERR
                     YIIAPRGVEVGQQLISGAEAPIKPGNALPIRNIPVGSTIHCIEMVPGKGAQLARAAGT
                     SVQLLAREGSYAQLRLRSGEIRRVHVECRATIGEVGNGEHGLRKIGKAGANRWRGIRP
                     TVRGVAMNPVDHPHGGGEGRTGEAREPVSPWGTPAKGYRTRSNKRTDGMIVQRRHKR"
     gene            4086..4361
                     /gene="rpsS"
                     /locus_tag="P5537_08785"
     CDS             4086..4361
                     /gene="rpsS"
                     /locus_tag="P5537_08785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018440478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HRV78175.1"
                     /translation="MARSIKKGPFIDAHLLKKVDAARTSNDKRPIKTWSRRSTILPDF
                     IGLTIAVHNGKQHIPVFVTENMVGHKLGEFALTRTFKGHAASKKAKR"
     gene            4371..4700
                     /gene="rplV"
                     /locus_tag="P5537_08790"
     CDS             4371..4700
                     /gene="rplV"
                     /locus_tag="P5537_08790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018987827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HRV78176.1"
                     /translation="METKAILRGVRLSAQKGRLVADLVRGMPVGRALDTLAFSPKKGA
                     KIIRKVLESAIANAEHNDGADIDALKVKTIHVEEGMTLKRFTARAKGRGNRILKPTCH
                     VYLTVGE"
     gene            4710..5480
                     /gene="rpsC"
                     /locus_tag="P5537_08795"
     CDS             4710..5480
                     /gene="rpsC"
                     /locus_tag="P5537_08795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002931590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000312 - plastid small ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HRV78177.1"
                     /translation="MGQKIHPTGFRLAVTRDWGSRWFANSKDYAGMLHEDLKVRDYLK
                     KRLAHASVGRVVIERPAKNARVTLYSARPGVVIGKKGEDIEALKRDLQKIVGVPVHVN
                     IEEVRKPELDAKLIADSIAQQLEKRIMFRRAMKRAMQNAMRLGAQGIKIMSAGRLNGA
                     EIARTEWYREGRVPLHTLRANIDYGVSEAKTTYGIIGIKVWVFKGEMLGRNEQPVAAE
                     PEADNRRGRRGAPRDGEGRPGRRPARRGEGRQEESRSE"
     gene            5480..5896
                     /gene="rplP"
                     /locus_tag="P5537_08800"
     CDS             5480..5896
                     /gene="rplP"
                     /locus_tag="P5537_08800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HRV78178.1"
                     /translation="MLQPTRRKYRKEQKGRNTGVATRGAKVSFGEYGLKAIGRGRLTA
                     RQIESARRAMTRHIKRGGRIWIRIFPDKPISKKPAEVRMGNGKGNPEYWVAEIQPGKV
                     LYEMDGVDEALAREAFRLAAAKLPIETVFVTRLIGG"
     gene            5899..6093
                     /gene="rpmC"
                     /locus_tag="P5537_08805"
     CDS             5899..6093
                     /gene="rpmC"
                     /locus_tag="P5537_08805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011767132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HRV78179.1"
                     /translation="MNATELRAKSADELNNELIELLKAQFSLRMQHATQQLGNTSQIG
                     KVRRDIARVRTILREKAGQQ"
     gene            6090..6359
                     /gene="rpsQ"
                     /locus_tag="P5537_08810"
     CDS             6090..6359
                     /gene="rpsQ"
                     /locus_tag="P5537_08810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011767131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HRV78180.1"
                     /translation="MSENVEKVRRALVGRVVSDKMQKTVTVLVERRVKHPLYGKIITR
                     SAKYHAHVEDGVAAQGDLVEIEECRPISRTKTWRVAKVLEKATII"
     gene            6516..6884
                     /gene="rplN"
                     /locus_tag="P5537_08815"
     CDS             6516..6884
                     /gene="rplN"
                     /locus_tag="P5537_08815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012728338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HRV78181.1"
                     /translation="MIQMQSKLDVADNSGARSVMCIKVLGGSKRRYAGVGDIIKVTVK
                     DAAPRGRAKKGDVYNAVVVRTAKGVRRPDGSLIKFDSNAAVLLNNKLEPIGTRIFGPV
                     TRELRTERFMKIVSLAPEVL"
     gene            6896..7213
                     /gene="rplX"
                     /locus_tag="P5537_08820"
     CDS             6896..7213
                     /gene="rplX"
                     /locus_tag="P5537_08820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011237983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HRV78182.1"
                     /translation="MNKIRKGDEVLVLTGKDRGRRGTVLRRVDDERVVVEGVNRVKKH
                     VRPNPLKGEVGGIVEKEMPIHVSNVALFNPATQKGDRVGIKTLEDGRKVRFFKSNGEL
                     VNA"
     gene            7223..7762
                     /gene="rplE"
                     /locus_tag="P5537_08825"
     CDS             7223..7762
                     /gene="rplE"
                     /locus_tag="P5537_08825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007875323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HRV78183.1"
                     /translation="MARLQQVYKDEVAPALQQQFGYKSVMEVPRITKITLNMGVGEAV
                     GDKKILEHAMGDMTKIAGQKPVSTKARKSIAGFKIRDGYPIGCMVTLRGPRMFEFLDR
                     LITIALPRVRDFRGIAAKGFDGRGNYNLGVKEQIIFPEIEYDKIDALRGMNISITTTA
                     KTDEEARALLGAFKFPFKN"
     gene            7770..8075
                     /gene="rpsN"
                     /locus_tag="P5537_08830"
     CDS             7770..8075
                     /gene="rpsN"
                     /locus_tag="P5537_08830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HRV78184.1"
                     /translation="MAKLALINREAKRAMLVEKYAAKRAALVAKVKDTSLSEEERMAA
                     RLALQQLPRNANPTRQRNRCALTGRPRGVFRKFGLCRNKLREIAFRGEVPGMTKASW"
     gene            8089..8484
                     /gene="rpsH"
                     /locus_tag="P5537_08835"
     CDS             8089..8484
                     /gene="rpsH"
                     /locus_tag="P5537_08835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011767126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HRV78185.1"
                     /translation="MSMSDPIADMLTRIRNGQQAQKASVSMPSSKLKVAIAKVLQDEG
                     YIDGFAVRDEAGKASLDVTLKYYAGRPVIERLERVSRPGLRIYKGSDDLPRVMNGLGV
                     AIVSTPRGVMTDRSARANRVGGEVICLVA"
     gene            8495..9028
                     /gene="rplF"
                     /locus_tag="P5537_08840"
     CDS             8495..9028
                     /gene="rplF"
                     /locus_tag="P5537_08840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004738786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HRV78186.1"
                     /translation="MSRVAKNPVAIPQGVEVMISDAEIAVKGPLGTLRQPLTGEVSVV
                     REGDAVVCKAREGAENARAMSGTVRALVNNMVTGVTKGFERKLTLVGVGYRAQAQGDK
                     LNLSLGFSHPVVHQMPEGVKVETPTQTEIVIKGSDKQKVGQVAAEVRAYRAPEPYKGK
                     GVRYSDEVVVLKETKKK"
     gene            9040..9393
                     /gene="rplR"
                     /locus_tag="P5537_08845"
     CDS             9040..9393
                     /gene="rplR"
                     /locus_tag="P5537_08845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005970258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HRV78187.1"
                     /translation="MNKKETRLRRARKTRAKIAELKAVRLTVFRSNCHIYAQIISGCG
                     SRVLAAASTVEPDVRAQVANGGNKAAAEAVGKLIAERAKAAGVEQVSFDRSGFLYHGR
                     VKALAEAAREGGLKF"
     gene            9406..9930
                     /gene="rpsE"
                     /locus_tag="P5537_08850"
     CDS             9406..9930
                     /gene="rpsE"
                     /locus_tag="P5537_08850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011237989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000312 - plastid small ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HRV78188.1"
                     /translation="MAKQQTKRAQASDERDDGLKEKMVAINRVTKVVKGGRILGFAAL
                     TVVGDGDGAIGMGKGKSREVPVAVQKAMDEARRKMRKVSLKNGTLQHTVMGKHGAASV
                     LMQPAPAGTGIIAGGPMRAVFEVMGVTDVICKCIGSANPYNVVRATINGLMAINTPAE
                     IAAKRGKTVEEILG"
     gene            9934..10116
                     /gene="rpmD"
                     /locus_tag="P5537_08855"
     CDS             9934..10116
                     /gene="rpmD"
                     /locus_tag="P5537_08855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HRV78189.1"
                     /translation="MSDKKIKVTLVKSVIGTKQSHRATVRGLGLRRLNHSVELADTPE
                     VRGMINKVSYLVKCEG"
     gene            10118..10555
                     /gene="rplO"
                     /locus_tag="P5537_08860"
     CDS             10118..10555
                     /gene="rplO"
                     /locus_tag="P5537_08860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002931612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HRV78190.1"
                     /translation="MRLNSIKPGEGSKKVARRVGRGIGSGLGKTCGRGHKGQKSRAGG
                     FHKVGFEGGQMPLQRRLPKRGFVSLTRARNVEVRLSELDKLPVDEVDLLTLKQAGVIA
                     ADALSAKVVLSGSISRKLVLRGVGATQGAKAAIEAAGGSVAAE"
     gene            10571..11896
                     /gene="secY"
                     /locus_tag="P5537_08865"
     CDS             10571..11896
                     /gene="secY"
                     /locus_tag="P5537_08865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HRV78191.1"
                     /translation="MANPAATLGSPGRFGDLKRRLLFLVGALIVYRIGAHIPVPGIDP
                     QGLAELFQSQQGGILGVFNLFSGGALSRFTIFALGIMPYISASIIMQLMTVAVPSLEA
                     LKKEGEAGRRKITQYTRYGTLVLALAQSLGIAIALEGQAGLVLEPGLMFRFVTVATLV
                     TGTMFLMWLGEQITERGIGNGISMIIFAGIIAGLPSAIGGLFELVRTGAMHPFTALFI
                     CILVVLVTAFVVFVERGQRKILVNYAKRQVGNKVYGGQSSHLPLKLNMSGVIPPIFAS
                     SIILFPATLGQWFGSSEGMYWLRDIASTLSPGQPIYVMLYAVAIVFFCFFYTALVFNA
                     RETADNLKKSGAFVPGIRPGDQTARYIDKILMRLTLAGAIYITLVCLLPEFLILKWNV
                     PFYFGGTSLLILVVVTMDFMAQVQAFVMSHQYESLLKKANFKGAGLPGR"
     gene            11901..12119
                     /gene="infA"
                     /locus_tag="P5537_08870"
     CDS             11901..12119
                     /gene="infA"
                     /locus_tag="P5537_08870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017185218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HRV78192.1"
                     /translation="MAKEDVIEMQGEVTENLPNATFRVRLENGHMVLGHISGKMRMHY
                     IRILPGDKVTVQLTPYDLTKGRIVFRTK"
     gene            12145..12258
                     /gene="rpmJ"
                     /locus_tag="P5537_08875"
     CDS             12145..12258
                     /gene="rpmJ"
                     /locus_tag="P5537_08875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020322760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HRV78193.1"
                     /translation="MRVQASVKRLCRNCKIIRRKGVVRVICSDPRHKQRQG"
     gene            12312..12674
                     /gene="rpsM"
                     /locus_tag="P5537_08880"
     CDS             12312..12674
                     /gene="rpsM"
                     /locus_tag="P5537_08880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011237994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HRV78194.1"
                     /translation="MARIAGVNIPNHKHAEIALTAIYGIGRSRAQKICDAAGIVRSVK
                     IKDLTETDMEKLRDEVARFVVEGDLRREVTMNIKRLMDLGCYRGVRHRRGLPLRGQRT
                     RTNARTRKGPRKPIAGKK"
     gene            12687..13076
                     /gene="rpsK"
                     /locus_tag="P5537_08885"
     CDS             12687..13076
                     /gene="rpsK"
                     /locus_tag="P5537_08885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HRV78195.1"
                     /translation="MAKTGTKVRKKVKKNVAEGIAHVHASFNNTIITITDRQGNALSW
                     ATSGGAGFKGSRKSTPFAAQVAAEAAGKVAQECGIKNLEVRIKGPGPGRESSVRALNA
                     LGIKISSITDITPIPHNGCRPPKKRRI"
     gene            13091..13720
                     /gene="rpsD"
                     /locus_tag="P5537_08890"
     CDS             13091..13720
                     /gene="rpsD"
                     /locus_tag="P5537_08890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011767115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HRV78196.1"
                     /translation="MARNLDPKCRQCRREGEKLFLKGEKCFTDKCSIERRAYAPGQHG
                     QRSGQRLSGYGVQLREKQKIRRIYGVLERQFRKVYAEADRRRGQTGENLLQLLEGRLD
                     AVAYRMGFGASRAEARQVVRHNGVLVNGKRVNIPSYVVRPGDVVELTERARGHLRVKA
                     ALEAAESRGFPEWLEVDAKAGKGTFKAYPVRSELPPTINEGLVVELYSR"
     gene            13754..14740
                     /gene="rpoA"
                     /locus_tag="P5537_08895"
     CDS             13754..14740
                     /gene="rpoA"
                     /locus_tag="P5537_08895"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018987844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HRV78197.1"
                     /translation="MLMQSNALLKPRIIDVQSTSPVQARVTMEPFERGFGHTLGNALR
                     RILLSSLPGHAPTEVTIEGVLHEYSTLDGVREDIVDLLLNLKGVVFKLNGRSEVTVRL
                     AKAGEGVVTAADIEVGHDVEIINPDHVIAHLAPGGKLDMQIKVEEGRGYVPGNSRPEN
                     GESKSIGRIVLDASFGPVRRVSYLVESARVEQRTDLDRLIIDIETNGAVDPEEAIRYA
                     ARVLMDQLSVFADLEGTAPERVETASPTIDPVLLRPVDDLELTVRSANCLKAENIYYI
                     GDLIQRTETELLKTPNLGRKSLNEIKEVLASRGLTLGMKLENWPPAGLEKLG"
     gene            14766..15164
                     /gene="rplQ"
                     /locus_tag="P5537_08900"
     CDS             14766..15164
                     /gene="rplQ"
                     /locus_tag="P5537_08900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005762 - mitochondrial large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HRV78198.1"
                     /translation="MRHRNGLRKLNRTSSHRQAMFRNMANSLLQHEVIKTTLPKAKEL
                     RRVVEPMITLGKKPSVANRRLAFNRLRDRDMVVKLFDELGPRYATRNGGYLRILKCGF
                     RDGDNAPMAYVELLDRPDVEAVEVEEAEAA"
     gene            15275..16297
                     /gene="galE"
                     /locus_tag="P5537_08905"
     CDS             15275..16297
                     /gene="galE"
                     /locus_tag="P5537_08905"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HRV78199.1"
                     /translation="MAVTLVTGGAGYIGSHTCVELLGAGQDVVVVDDLSNASYEAVRR
                     IEELGGKRLAAFVEGDVRDGAVLARIFAEHEVAAVIHFAAKKAVGESVSQPLAYYDNN
                     LQGLLSVLQAMDAAGCRRMVFSSSATVYGDPASVPIREDFPTTATNPYGWTKLMGEQI
                     LRDLAASDARWNVVLLRYFNPVGAHASGRIGEDPDGLPNNLMPFVSQVAVGRLPRLRV
                     FGDDYPTPDGTGVRDYIHVVDLALGHLRALERIGELPGVTTLNLGTGRGYSVLEMVRA
                     FEAASGRPVPFDIVARRPGDIAACWADPAHAERVLGWRAQRDLQAMCEDAWRWQSGNP
                     RGYASA"
     gene            complement(16368..19190)
                     /gene="uvrA"
                     /locus_tag="P5537_08910"
     CDS             complement(16368..19190)
                     /gene="uvrA"
                     /locus_tag="P5537_08910"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HRV78200.1"
                     /translation="MDQIRIRGARTHNLRNVSLDLPRNRLTVITGLSGSGKSSLAFDT
                     LYAEGQRRYVESLSAYARQFLQLMEKPDVDLIEGLSPAIAIEQKATSHNPRSTVGTVT
                     EIHDYLRLLYARAGTPHCPDHPQHALEAQSVAQMVDHVLALPEDTKLMILAPVVAGRK
                     GEQGDLFADLRAQGFVRVRVDGEVMELDALPALEKGRRHNVEVVIDRVKVRADLRGRL
                     AESFETALTHADGRALAVEMDSGREHLFSARFACPVCGFALAELEPRLFSFNNPAGAC
                     PKCDGLGEVEFFDPARVVAHPELSLASGAIRGWDRRNQFYFQMLASLAAHYGFDIETP
                     WEALPARVREIVLDGSGRTKIAFRYMADNGRMVLKEHPFEGILPNLERRLRETDAVAV
                     REELSKYRATRPCPACHGTRLRSEARHVLVGGRALHEVGRMPLGGCRDFFATLQLAGA
                     RAQVAERIVREIADRLGFLIDVGLDYLSLDRSADTLSGGEAQRIRLASQIGSGLTGVM
                     YVLDEPSIGLHQRDNDRLLATLARLRDLGNTVIVVEHDEDAIRSADYLVDMGPGAGEH
                     GGEVVAHGTPDEVIASPHSVTGAYLAGRRRIAIPTRRARPDPECHLRIVGARGNNLKA
                     VEVALPVGLFTCITGVSGSGKSTLINDTLARAAAHRLNGAATEPAPHDAIEGLQHFDK
                     LIDVDQSPIGRTPRSNPATYTGLLTPIRELFAGVPEARARGYSPGRFSFNVRGGRCEA
                     CQGDGLVKVEMHFLPDMYVPCDVCHGRRYNRETLEIRYKGRTIDEVLGMTVEQALDFF
                     SAVPAIARKLETLTDVGLGYIRLGQSATTLSGGEAQRVKLALELSRRDTGRTLYILDE
                     PTTGLHFQDIEMLLAVLQRLREHGNTIVVIEHNLDVIKTADWLVDMGPEGGGGGGTVV
                     CCGTPEEVAAHPASHTGRHLRRVLGG"
     gene            19330..20511
                     /locus_tag="P5537_08915"
     CDS             19330..20511
                     /locus_tag="P5537_08915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HRV78201.1"
                     /translation="MTREERRAGMGLAAIFALRMLGLFLILPVFAVHAATIPGGDDLT
                     LVGLAIGAYGLTQACLQIAYGAASDRFGRKPVIVFGLVLFVLGSVVAAMADGIHMIIV
                     GRVLQGAGAISAAVTALAADLTRDQHRTKVMAMIGSSIGLVFALSMVAAPLLYAAVGM
                     DGIFWLTAVLAAGAIGVLLWAVPVAPPVPRATGRLIDVLRDGQLMRLNFGVFALHLIQ
                     TTMWVMVPSALVAGGGLPMPEHWKVYLPAVLLSFVVMVPAVIVAERRDKLKPVFNAAI
                     VLLALVQIGLWLFGDGLIPLALLLTLFFVAFNVLEATQPSWISRIAPPGSKGTALGVY
                     NTLQSIGLFLGGVLGGWLGQTFGPAAVSLSCAALALLWLALASTMNPPPLRAAPAGAP
                     R"
     gene            20581..21081
                     /gene="ssb"
                     /locus_tag="P5537_08920"
     CDS             20581..21081
                     /gene="ssb"
                     /locus_tag="P5537_08920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HRV78202.1"
                     /translation="MASVNKVILIGNLGADPESRFAPSGDAICNIRLATTETWRDKNT
                     GERREATEWHRVAFFGKLAEIAGQYLRKGSQVYIEGSLRTRKWQDQSGQDRYTTEIRA
                     DEMKMLGRREGGDAPMRGGEGGWDAGGQSAPARQPAAPAQRPQPQSAPPQQSGGFGDF
                     DDDIPF"
     gene            21198..22160
                     /locus_tag="P5537_08925"
     CDS             21198..22160
                     /locus_tag="P5537_08925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HRV78203.1"
                     /translation="MKDLIHYGDGVHAIDSGYGRPQLAAIHVIVQDGRAAVVDTASNA
                     SVPRILGALAALGIAPEAVDWVLLTHIHLDHAGGAGSLMCALPQAKLLVHPRGLRHMI
                     DPSKLWEATCAVYGPERAFDLYGQLVPVPAERIVPATDGLEIHLGSRMLRVLDTPGHA
                     RHHICIWDSVARAFFTGDTFGLSYRELDVDGRAFVVPTTTPTQFDPEGMHASIDRMLA
                     MRPQAMYLTHYSRVVDVDRLGADLHRLIDTMLAVAEAARGDGAARHVEIVAGLEQIFR
                     EEAARQNWALGEDETLELLRMDLELNAQGLGVWLDSRQTSAAGA"
     gene            22168..22992
                     /locus_tag="P5537_08930"
     CDS             22168..22992
                     /locus_tag="P5537_08930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="HRV78204.1"
                     /translation="MTVATTDRARRFGGIDRLYGAGAAARLAGAHACVIGIGGVGSWA
                     AEALARSGVGRLTLIDLDHVAESNINRQAHALEDTLGMAKVGAMAARIAGIDPDCRVT
                     TIEDFLTPENAGALLQGYDLVIDAIDNVRAKVAIAVTCTQRRIPLVMAGGAGGKRDPA
                     RIGADDLARTEQDPLLAKVRARLRKEHGFPRDPRKKFGIEAVFSTEPLRFPEVDACDA
                     AHPGAASAPQGLACAGYGSSMAVTASVGLLCAARALEHLLRQAEAPARGATPEPSA"
     gene            22989..23375
                     /locus_tag="P5537_08935"
     CDS             22989..23375
                     /locus_tag="P5537_08935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CbiX/SirB N-terminal domain-containing protein"
                     /protein_id="HRV78205.1"
                     /translation="MNAANPSASALVLFGHGARDPEWAGPMRRIREAALARPGAPRVE
                     LAFLEFMTPTLPEAIAALAAEGARKVAVVPIFLAQGGHLKRDLPVLLEEARAAHPGCE
                     ITLATAAGEADPVVAAMADYALGCLG"
BASE COUNT         4075 a         7643 c         7911 g         3794 t
ORIGIN      
        1 cacgtcaacg tcggcaccat cggccacgtc gaccatggca agaccacgct gaccgctgcg
       61 atcaccacca tcctgtcgaa gaagttcggc ggcgaggcga aggcctacga ccagatcgac
      121 gcggcgcccg aagagaaggc gcgcggcatc accatcaaca ccgcgcacgt cgagtacgag
      181 accgccacgc gccactacgc gcacgtggac tgcccgggtc acgccgacta cgtgaagaac
      241 atgatcaccg gtgccgccca gatggacggc gcgatcctgg tgtgctcggc cgcggacggc
      301 ccgatgccgc agacccgcga gcacatcctg ctggcgcgtc aggtcggtgt gccgtacatc
      361 atcgtgttcc tgaacaagtg cgacatggtc gacgacgagg aactgctcga gctcgtcgag
      421 atggaagtgc gcgagctgct gtcgaagtac gacttcccgg gcgacgacat ccccatcgtc
      481 aagggttcgg cgctgaaggc gctcgagggc gaccagtccg acatcggcga gccggcgatc
      541 ttccgcctgg ccgacgcgct cgacagctac atcccgactc ccgagcgtgc gatcgacaag
      601 cccttcctgc tgccgatcga ggacgtgttc tcgatctcgg gtcgcggcac cgtggtgacc
      661 ggtcgtgtcg agcgcggcat cgtcaaggtc ggcgaggaaa tcgagatcgt cggcatcaag
      721 ccgaccgtca agaccacctg caccggcgtc gagatgttcc gcaagctgct cgaccagggc
      781 caggctggcg acaacgtggg cgtgctgctg cgcggcacca agcgtgaaga cgtcgagcgc
      841 ggccaggtgc tgtgcaagcc gggttcgatc accccgcaca cccacttcac cggcgagatc
      901 tacgtgctgt cgaaggaaga gggtggtcgt cacaccccgt tcttcaacaa ctaccgtccg
      961 cagttctact tccgcactac cgacgtgacc ggttcgatct cgctgcccga aggcaccgag
     1021 atggtcatgc cgggcgacaa cgtgtcgatc accgtcaagc tgatcgcccc gatcgccatg
     1081 gaagaaggtc tgcgcttcgc gatccgtgaa ggcggccgca ccgtcggcgc cggcgtcgtc
     1141 gccaagatca tcgagtaagt actcgatccg gggcgactcc tgccgggtcg ccccgtcgct
     1201 ctttgcgctc ttttttcgca gtaccagctc tttaggaaga acatcatgca gaaccagaag
     1261 atccgcatcc gcctgaaagc cttcgactac cgcctgatcg atcagtcggc gctcgagatc
     1321 gtcgataccg ccaagcgcac cggcgccgtg gttcgtggtc ccgtgccgct gccgacccgc
     1381 atcgagcgct tcgacctgct gcggtcgccg cacgtcaaca aggcctcgcg cgaccagatg
     1441 gaaatccgta cgcaccagcg cctgatggac atcatcgacc cgaccgacaa gacggtcgac
     1501 gcgctgatga agctggacct gcctgccggc gtggatgtcg agatcaagct ccagtaagca
     1561 cgcattgctt gcggaagttt cgaacaggcc ggtataatcc ggcctttgtg ccttttggcg
     1621 cattaattgt gacccccggt caatcgcaac cgggattcag gagaaaaaaa tgagtctagg
     1681 ccttgttgga cgcaaggtcg gcatgactcg catcttcgct gaggatggca agaccatccc
     1741 ggtgacggtg cttgacgtgt cggacaatcg tgtgtcccag atcaagacga tcgacaccga
     1801 cggctatgcc gcggtgcaga ttgcttatgg caagcgccgc gccagccgga tcaccaagcc
     1861 ggtcgcgggt catcttgcca aggcgggcgt cgagccctgc cgcggtatca aggaattccg
     1921 cgtcgaagcc gagcaggccg gtggcatgaa cgccggcgat gcgatcggtg cggacctctt
     1981 ccaggtcggc cagaaggtcg atgtcaccgg cgtgacgatc ggcaagggct tctcgggccc
     2041 gatcaagcgt cacaacttct cgtcgaaccg cgcctcgcac ggtaactcga tctcgcacaa
     2101 ctcccccggc tccatcggta tggcgcagga tccgggtcgt gtgttccccg gcaagcgcat
     2161 ggcgggccag tacggcaacg tccagcgcac cacgcagggt ctcgagatcg ttcgtgtgga
     2221 cgtcgagcgc cagctccttc tcgtgaaggg tgcggtgccg ggtgccaagg gtggcgacgt
     2281 cgtcgtccgt ccggcggtca aggcctgagg agcgcgcaat ggaattgaaa ctcttgaacg
     2341 atcagggtca ggctgcgtcg acgctcgagg cgtccgatgt gctgttcggc cgtgactaca
     2401 acgaagccct ggtgcaccag gtggtgactg cttaccttgc gaatgcccgt tccggcaacc
     2461 gcaagcagaa gggtcgctcc gagatcgcca agtcgacccg caagccgttc cgccagaagg
     2521 gtacgggcaa cgcccgcgcc ggtatggcgt cgagcccgct gtggcgtggc ggcggcaaga
     2581 tcttcccgaa tactcccgac gagaacttca gccagaaggt caatcgcaag atgtaccgcg
     2641 ccggtgtggc tgcgatcctg tcgcagctcg ctcgcgagga ccgtctggcg gtggtcgaga
     2701 acttcagcgt cgaggcgccg aagacccgcc tgctgtcgca gaagctcaag gggatgggcc
     2761 tggattcggt cctggtcatc accgacgaaa tcgacgaaaa cctgttcctg tcctcgcgca
     2821 acctccacca ggttctggtg ctggaagtga acgaggcgga tccggtgtcg ctcgtgcgtt
     2881 tccccaaggt gctcgtcacc aagggcgcgc tggcgaagat ggaggaagcg tggcaatgag
     2941 cgcgatcagt caggaacgtc tgctgcaggt gctgctcgcc ccgcagatct ccgagaaggc
     3001 gaccttcgtc gccgacaaga acgagcaggt ggtgttcaag gtggcgtccg acgcaaccaa
     3061 gcccgaagtg aaggcggcgg tcgagtcgct gttcaaggtc gaggtgaagt cggtccagat
     3121 cctgaacgtg aagggcaagg ccaagcgctt tggcaagacc atgggtcgcc gcaaggactg
     3181 gaagaaggct ttcgtgtgcc tgaagccggg ccaggaaatc aactttgcgg ctggggagtg
     3241 atagatcatg gcaatcgtta aactgaagcc tacgtctgcc ggtcgtcgcg cccaggtcaa
     3301 ggtggtgaac cccgatctgt acaagggccg cccggtcgac gcgctgatcg agaagcagac
     3361 caagaacgcc ggccgcaaca actacggccg cgtgacgatg cgccaccagg gtggcggtca
     3421 caagcagcac tatcgcctgg tggatttccg tcgcaacaag gacggcattc cggccaaggt
     3481 cgagcgtatc gagtacgacc cgaaccgctc cgcgcacatc gcgctgctgt gctacgccga
     3541 tggcgagcgc cgctacatca tcgccccgcg cggtgtggaa gtcggccagc agctgatcag
     3601 cggcgccgag gcgccgatca agccgggcaa cgccctgccg atccgcaaca tcccggtcgg
     3661 ctcgacgatc cactgcatcg agatggttcc cggcaagggc gcccagctcg cgcgcgccgc
     3721 cggcacttcg gtgcagctgc tcgctcgcga aggctcgtat gcccagctgc gcctgcgttc
     3781 cggcgagatt cgccgcgtgc acgtcgagtg ccgcgcgacg atcggtgaag tcggcaacgg
     3841 cgagcatggt ctgcgcaaga tcggcaaggc cggtgcgaac cgctggcgcg gcatccgccc
     3901 gaccgtccgc ggcgtggcga tgaacccggt ggatcacccg cacggtggcg gcgagggccg
     3961 taccggcgag gcgcgcgaac cggtcagccc gtggggcacg ccggccaagg gctatcggac
     4021 gcgttcgaac aagcgcaccg acggcatgat cgtgcagcgt cgtcacaagc gttaaggggt
     4081 aaaagatggc acgttctatc aagaaaggcc cgttcatcga cgcgcacctg ctcaagaagg
     4141 tcgacgcggc tcggacgagc aacgacaagc gcccgatcaa gacctggtcg cgccgctcca
     4201 cgatcctgcc cgacttcatc ggcctgacga tcgcggtgca caacggcaag cagcacattc
     4261 cggtgttcgt gaccgagaac atggtcggtc acaagctggg cgaattcgcg ctgacgcgga
     4321 ccttcaaggg tcacgccgcc agcaagaagg ccaagcgtta aggggacgac atggaaacca
     4381 aagctattct ccgtggcgtt cgcctgtcgg cccagaaggg ccgcctcgtg gccgatctgg
     4441 tccgcggcat gcctgtcggc cgtgcgctcg acaccctggc cttctcgccc aagaagggcg
     4501 cgaagatcat ccgcaaggtg ctcgagtcgg cgatcgccaa cgccgagcac aacgacggtg
     4561 ccgacatcga cgcgctgaag gtcaagacca ttcacgtgga agagggcatg acgctcaagc
     4621 gcttcaccgc gcgtgcgaag ggtcgcggca accgcatcct gaagcccacc tgccacgtct
     4681 acctgaccgt tggcgagtaa ggagtaatca tgggtcagaa aatccatccc accgggttcc
     4741 gcctcgccgt cacgcgtgac tggggctcgc gctggttcgc caacagcaag gactacgccg
     4801 gcatgctgca cgaggacctc aaggtccgcg actacctgaa gaagcgcctc gcgcacgctt
     4861 cggtgggccg tgtggtcatc gagcgtcccg ccaagaacgc ccgcgtcacc ctgtacagcg
     4921 cccgcccggg cgtcgtcatc ggcaagaagg gcgaggacat cgaggcgctc aagcgcgatc
     4981 tgcagaagat cgtcggcgtg ccggtccacg tgaacatcga ggaagtgcgc aagcccgagc
     5041 tcgacgccaa gctcatcgcc gactcgatcg cccagcagct cgagaagcgc atcatgttcc
     5101 gtcgcgccat gaagcgcgcg atgcagaacg ccatgcgcct cggtgcccag ggcatcaaga
     5161 tcatgagcgc cggccgcctg aacggtgccg agatcgcccg caccgagtgg taccgcgaag
     5221 gccgtgtgcc gctgcacacc ctgcgcgcca acatcgacta cggtgtttcc gaggccaaga
     5281 cgacctacgg catcatcggc atcaaggtgt gggtgttcaa gggcgagatg ctgggccgca
     5341 acgagcagcc cgtggccgcc gagccggaag ccgacaaccg ccgcggccgc cgtggcgccc
     5401 cgcgggacgg cgagggccgt ccgggtcgtc gtcccgcccg tcgtggcgaa ggccggcaag
     5461 aagaaagcag gagtgaatga tgctgcagcc gactagaagg aagtatcgga aggagcagaa
     5521 gggtcgcaac accggcgtcg ccacccgcgg cgcgaaggtg tcgttcggcg agtatggcct
     5581 caaggccatc ggacgcggtc gcctgaccgc tcgccagatc gagtcggccc gtcgtgcgat
     5641 gacccgtcac atcaagcgtg gcggccgcat ctggatccgg attttcccgg acaagccgat
     5701 ttcgaagaag cccgccgagg tccgcatggg taacggcaag ggcaaccccg aatactgggt
     5761 cgccgagatc cagccgggca aggtgctgta cgagatggac ggggttgacg aggccctggc
     5821 gcgcgaggcc ttccgccttg cggccgccaa gctgccgatc gagaccgtgt tcgtcacccg
     5881 actgattggg ggttgaacat gaacgctacg gaactccgcg ccaagagcgc cgacgagttg
     5941 aacaatgaac tgatcgagct gctgaaggcc cagttttcgc tgcgcatgca gcacgccacg
     6001 cagcaactcg gcaacacgag tcagatcggg aaggttcgcc gcgacatcgc gcgcgtgcgc
     6061 accatcctgc gtgaaaaggc gggtcagcaa tgagcgagaa cgtcgagaag gttcgccgcg
     6121 cgctggttgg gcgtgtggtg agtgacaaga tgcagaagac ggtgaccgtt ctggtcgagc
     6181 gccgggtcaa gcacccgctg tacggcaaga tcatcacgcg ttcggcgaag taccacgcgc
     6241 acgtcgagga cggcgtcgcg gcccagggcg acctggtcga gatcgaggag tgccgtccga
     6301 tctcgcgcac caagacctgg cgcgtggcca aggtgctcga gaaggcgacg atcatctgat
     6361 tcgagttgca agcagcgagc agtgaataaa cagcttggca ccccggtgcc aggctgttat
     6421 aattttgcct ctttgctccg gggctcgctc ggggcatcct accctgacgg gttccaagac
     6481 tgtccgcgca tgcgggataa gttggagata ctttcatgat tcaaatgcag tccaagctgg
     6541 acgtggccga taactccggc gcgcgctcgg tgatgtgcat caaggtcctg ggtggttcga
     6601 agcgccgcta cgccggcgtg ggcgacatca tcaaggtcac cgtgaaggat gccgcgccgc
     6661 gtggtcgtgc caagaaaggc gacgtctata acgcggtcgt cgtgcgcacc gccaagggcg
     6721 ttcgtcgtcc cgatggttcg ctgatcaagt tcgacagcaa tgcggccgtg ctcctgaaca
     6781 acaagctcga gccgatcggc acccgtatct tcgggccggt cacgcgcgag ctgcgcaccg
     6841 agcggttcat gaagatcgtc tcgctggcgc ccgaagtgct ctgaggagtc cagagatgaa
     6901 caagatccgc aagggtgacg aagttttggt gctgacgggc aaggatcgtg gtcgtcgcgg
     6961 caccgtgctg cgccgcgtcg atgacgagcg cgtcgtggtc gagggcgtga accgggtgaa
     7021 gaagcatgtg cgcccgaatc cgctgaaggg tgaagtgggt ggcatcgtcg agaaggagat
     7081 gccgatccat gtttcgaacg tcgcgctgtt caatcccgcc acccagaagg gtgatcgcgt
     7141 cgggatcaag acgcttgaag acggccgcaa ggttcgcttc ttcaagtcga acggcgagct
     7201 ggtgaacgcc taaggagtga cgatggctcg cttgcaacag gtttacaagg acgaagtcgc
     7261 gccggcgctg cagcagcagt tcggctacaa gtccgtcatg gaagtgccgc gcatcaccaa
     7321 gatcaccctc aacatgggtg tcggtgaggc tgtcggcgac aagaagattc tcgagcacgc
     7381 catgggcgac atgaccaaga tcgcgggtca gaagccggtt tcgaccaagg cgcgcaagtc
     7441 gatcgcgggt ttcaagatcc gtgacggcta cccgatcggc tgcatggtga ccctgcgtgg
     7501 cccgcgcatg ttcgagttcc tcgatcgcct gatcacgatc gcgctgccgc gtgtccgcga
     7561 cttccgtggc atcgctgcca aggggttcga cggtcgtggc aactacaacc tcggcgtgaa
     7621 ggagcagatc atcttccccg agatcgagta cgacaagatc gacgcgctgc gcgggatgaa
     7681 catcagcatc acgacgacgg cgaagaccga cgaggaagcc cgtgctctcc tcggcgcgtt
     7741 caagttcccg ttcaagaatt gagggtgata tggcgaaact cgctctgatc aaccgcgaag
     7801 cgaagcgtgc gatgctggtg gaaaagtatg ccgccaagcg cgccgccctg gtcgcgaagg
     7861 tcaaggacac cagtctgtcc gaagaagaac gcatggctgc ccgcctggcc ctgcagcaac
     7921 tgccgcgcaa cgccaacccg acccgccagc gtaaccgctg cgcgctgacc gggcgcccgc
     7981 gtggtgtctt ccgcaagttc ggtctgtgcc gcaacaagct gcgcgagatc gctttccgcg
     8041 gcgaagtgcc tggcatgacc aaggcgagct ggtaaggaga attcgaagat gagtatgtcc
     8101 gatccgatcg ccgacatgct gacgcgcatc cgcaacggcc agcaggccca gaaggcctcg
     8161 gtgtcgatgc cttcgtccaa gctgaaggtt gcgatcgcca aggtgttgca agacgagggt
     8221 tacatcgacg gcttcgccgt ccgtgacgag gccggcaagg cttcgctcga cgtcaccctc
     8281 aagtactacg ccggtcgtcc ggtcatcgag cgcctggagc gtgtgagccg tcccggcctg
     8341 cgcatctaca agggcagcga cgatctgccg cgcgtgatga acggcctcgg cgtggccatc
     8401 gtttccacgc cgcgtggcgt gatgaccgac cgctcggcgc gtgcgaatcg cgtcggtggt
     8461 gaagtcatct gcctcgtcgc ctaaggggga tacgatgtct cgtgtagcca agaatccggt
     8521 cgcgatcccg cagggcgtgg aagtgatgat ttccgacgcc gagatcgcag tgaaggggcc
     8581 tctgggtacc ctgcgccagc cgctgaccgg cgaggtcagt gtggtccgtg aaggtgatgc
     8641 ggtggtgtgc aaggcgcgtg aaggcgccga gaacgcccgc gccatgtccg gcaccgtgcg
     8701 cgccctggtc aacaacatgg tgaccggtgt gaccaagggc ttcgagcgca agctcaccct
     8761 ggtcggcgtg ggttatcgcg cgcaggctca gggcgacaag ctcaacctgt cgctcggttt
     8821 ctcgcatccg gtggtccacc agatgccgga aggcgtgaag gtcgagaccc cgacccagac
     8881 cgaaatcgtg atcaagggtt ccgacaagca gaaggtcggc caggtcgctg ccgaggtgcg
     8941 tgcctaccgc gctcccgagc cttacaaggg caagggcgtc cgttactcgg acgaggtggt
     9001 ggtgctcaag gaaaccaaga agaagtaagg cggttcgtca tgaacaagaa agaaactcgt
     9061 cttcgccgtg cgcgcaaaac tcgcgccaag attgcggagc tcaaggcggt tcgcctgacg
     9121 gtgttccggt ccaactgcca catctacgcc cagatcatct ccggttgcgg ttcccgcgtg
     9181 ctcgcggcgg cttccaccgt ggagccggat gtgcgtgccc aggtcgcgaa cggcggcaac
     9241 aaggccgccg ccgaagcggt cggcaagctg attgccgagc gtgccaaggc tgccggcgtc
     9301 gagcaggtgt ccttcgaccg ctcgggcttc ctgtatcacg gccgcgtgaa ggcgctggcc
     9361 gaggccgccc gcgaaggcgg tctcaagttc taagcgagga atcgtatggc caagcagcaa
     9421 accaaacgtg cgcaagcctc cgacgagcgc gatgacggcc tgaaggaaaa aatggtcgcg
     9481 atcaatcgcg tgaccaaggt cgtcaagggc ggtcggatcc tcggcttcgc cgcgctgacc
     9541 gtggtcggcg acggggacgg cgcgatcggc atgggcaagg gcaagtcccg cgaagtgccg
     9601 gtggcggtgc agaaggcgat ggacgaagcg cgtcgcaaga tgcgcaaggt ctcgctcaag
     9661 aacggcaccc tgcagcacac cgtgatgggc aagcacggcg ccgcctcggt gctgatgcag
     9721 cccgctccgg ccggtaccgg catcatcgcg ggcggcccga tgcgcgccgt gttcgaagtc
     9781 atgggcgtga ccgacgtgat ctgcaagtgc atcggctccg ccaatccgta caacgtcgtc
     9841 cgtgccacga tcaacggcct gatggcgatc aacaccccgg cggagatcgc tgccaagcgc
     9901 ggcaagaccg tcgaagagat cctggggtaa gagatgtcgg acaagaaaat caaggtgacg
     9961 ctcgtcaaga gcgtgatcgg caccaagcag tcccaccgcg ccaccgtgcg cggcctcggt
    10021 ctgcgtcggc tcaaccattc ggtcgagctg gcggataccc ccgaggtgcg cgggatgatc
    10081 aacaaggtgt cctacctggt caagtgcgag ggttgaaatg cgcctgaata gcatcaagcc
    10141 cggtgagggt tcgaagaagg tcgcgcgccg agtcggtcgt ggcatcggca gcggcctggg
    10201 gaagacctgc ggccgcggcc acaagggtca gaagtcccgc gccggcggct tccacaaggt
    10261 cggtttcgag ggcggccaga tgccgctgca gcgtcgcctg ccgaagcgcg gcttcgtgtc
    10321 gctgacgcgc gcgcgcaacg tcgaggtgcg cctgtccgag ctcgacaagc tgccggtgga
    10381 tgaggttgat ctgctgacgc tcaagcaggc cggcgtgatc gccgctgacg cgctgtcggc
    10441 gaaggtcgtg ctgtccggtt cgatcagccg caagcttgtc ctgcgcggcg tcggtgccac
    10501 ccagggtgcg aaggcggcga tcgaagccgc tggcggctcc gtggcggccg agtaacaaaa
    10561 ggatacggtt gtggcgaatc ctgctgccac gctgggaagc cccggtcggt tcggcgatct
    10621 caagcgtcgc ctgctgttcc tggtaggcgc gctgatcgtc tatcgcatcg gtgcgcacat
    10681 cccggttccg ggaatcgacc cgcaggggct ggccgagttg ttccagtccc agcagggcgg
    10741 catcctgggc gtgttcaacc tgttttcggg cggcgccctt tcgcgcttca cgatcttcgc
    10801 gctgggcatc atgccctata tctccgcgtc catcatcatg cagttgatga ccgtggcggt
    10861 gccctcgctg gaggcgttga agaaggaagg cgaggctgga aggcgcaaga tcacgcagta
    10921 cacgcgatac ggcacgctcg tgctcgcgct cgcccagtcc ctgggcatcg cgatcgcgct
    10981 ggaagggcag gccgggctgg ttctcgagcc ggggctcatg ttccgcttcg tgaccgtggc
    11041 gacgctggtg accgggacga tgttcctgat gtggctgggt gagcagatca ccgagcgcgg
    11101 catcggcaac ggcatctcga tgatcatctt cgctggcatc atcgccgggc tgccgagtgc
    11161 gatcggcggg ctgttcgagc tggtgcgtac gggggccatg catcccttca ccgcgctctt
    11221 catctgcatc ctggtggtgc tggtgacggc cttcgtggtg ttcgtggagc ggggccagcg
    11281 caagatcctg gtcaactacg cgaagcgcca ggtcggcaac aaggtgtacg gcgggcaaag
    11341 ctcgcacctg ccgctgaagc tgaacatgtc gggcgtgatc ccgccgatct tcgcttcgag
    11401 catcatcctg ttcccggcga cgctggggca gtggttcggc tcctccgagg gcatgtactg
    11461 gttgcgggac atcgcatcca cgctatctcc gggacagccg atctacgtga tgctctatgc
    11521 ggtggcgatc gtgttcttct gcttcttcta tacggcgctg gtgttcaacg cccgcgaaac
    11581 tgcggacaac ctgaagaaga gcggggcctt cgttcccggg atccgtcccg gcgaccagac
    11641 cgcgcgctac atcgacaaga ttctcatgcg gcttacgctg gctggggcga tctacatcac
    11701 cctcgtctgc ctgctgccgg agttcctgat cctgaagtgg aacgtcccgt tctatttcgg
    11761 cggcacctcg ctgctgatcc tcgtggtcgt cacgatggac ttcatggccc aggtccaggc
    11821 gttcgtgatg tcgcaccagt acgagagtct gctgaagaag gcgaatttca agggggcggg
    11881 tctgcccggc aggtgagcgc atggcgaagg aagatgtcat cgagatgcaa ggtgaggtca
    11941 ccgagaacct tcccaacgca acgttccgcg tcaggctaga aaacggtcac atggtccttg
    12001 gacacatctc cggaaagatg cggatgcact acatccgcat ccttcccggt gacaaggtga
    12061 ccgtacagct caccccctac gacctgacca agggccggat cgttttccgg accaagtgaa
    12121 agttaaagaa acaggagcaa gaccatgaga gtccaggcct cagtcaagcg gctctgccgc
    12181 aactgcaaga tcatccgccg caagggtgtg gttcgcgtca tttgcagcga tccgcggcac
    12241 aagcaacgcc agggttgatc tactcaaccg caggcattag aatttaacgt ttttcgtttc
    12301 ggggtatacg gatggcccgt attgctgggg taaacattcc caatcacaag catgccgaga
    12361 tcgcgctgac cgccatctat gggatcggcc gttcgcgtgc tcagaagatt tgcgacgctg
    12421 ccggcatcgt tcgctcggtg aagatcaagg atctcaccga gaccgacatg gagaagctgc
    12481 gtgacgaagt cgcgcgcttc gtggtcgaag gcgacctgcg tcgtgaagtc acgatgaaca
    12541 tcaagcgcct gatggacctg ggctgctatc gcggcgtccg tcatcgtcgc ggcctgccgc
    12601 ttcgcggtca gcgcacccgc accaatgcgc gtacccgcaa gggcccgcgc aagccgatcg
    12661 ccggcaagaa gtaataggat ccgataatgg ctaagactgg aaccaaggtt cgcaagaagg
    12721 tcaagaagaa cgtcgcggaa ggcattgcgc acgttcacgc gagcttcaac aacaccatca
    12781 tcaccatcac cgaccgccag ggcaatgccc tgtcgtgggc gacttcgggc ggcgccggct
    12841 tcaagggttc gcgcaagagc accccgttcg ctgcgcaggt cgcggccgag gcggccggca
    12901 aggtggcgca ggaatgcggc atcaagaacc tcgaggttcg catcaagggc cccggcccgg
    12961 gtcgcgagtc ctcggttcgt gcgctcaacg cgctggggat caagatttcc agcatcacgg
    13021 acatcacccc cattccgcac aacggctgcc gtccgccgaa aaagcgccgt atctgacaag
    13081 gagttgataa gtggctcgta atctcgatcc caagtgccgt cagtgccgtc gcgaaggcga
    13141 aaagctgttt ctgaagggcg aaaagtgctt caccgacaag tgctccatcg agcgccgcgc
    13201 ctacgcgcct ggccagcacg gccagcgctc cggccagcgc ctgtcgggct atggcgttca
    13261 gctgcgtgaa aagcagaaga tccgccgcat ctacggcgtg ctcgagcgcc agttccgcaa
    13321 ggtgtatgcc gaagccgacc gccgtcgcgg tcagaccggc gaaaacctgc tccagttgct
    13381 ggaaggccgc ctggacgccg tcgcctatcg catgggcttc ggtgcttcgc gtgccgaggc
    13441 gcgccaggtc gtgcgtcaca acggcgtgct ggtcaatggc aagcgcgtca acattccgtc
    13501 gtatgtggtt cgtccgggcg acgtggtgga gctgaccgag cgtgcgcgtg gtcacctgcg
    13561 cgtcaaggca gccctcgagg ccgccgaatc gcgtggcttc cccgagtggc tcgaggtgga
    13621 cgccaaggcc ggcaagggca ccttcaaggc ctatccggtg cgcagcgagc tgcccccgac
    13681 gatcaacgaa ggcctggtcg tggaactgta ctcccgctga gcggggggct gatcctcttc
    13741 tagttccgag gaaatgctga tgcaaagcaa tgcactgctg aaaccgcgca tcatcgacgt
    13801 ccagagcacc tcgcccgtcc aggcgcgggt gacgatggag ccgttcgagc gcggttttgg
    13861 tcacacgctg gggaatgcgc ttcggcgcat cctcctgtcg tcgcttcccg gccacgcgcc
    13921 gaccgaagtg acgatcgaag gggtgcttca cgagtactcc acgctcgacg gcgtccgcga
    13981 ggacatcgtc gatctgctgc tcaacctgaa gggcgtggtg ttcaagctca acgggcgcag
    14041 cgaggtcacc gttcgtctcg ccaaggccgg cgaaggcgtg gtgaccgcgg ccgacatcga
    14101 ggtcggtcac gacgtcgaga tcatcaatcc cgaccatgtg atcgcccacc tcgcgccggg
    14161 cggcaagctc gacatgcaga tcaaggtcga ggaagggcgc ggctacgtgc cgggcaattc
    14221 ccgtcccgag aatggtgaga gcaagtcgat cggtcgcatc gtgctcgatg cctccttcgg
    14281 tcccgtgcgc cgcgtcagct acctcgtcga gagcgcccgc gtcgagcagc gcaccgacct
    14341 ggaccgtctg atcatcgata tcgagaccaa cggcgctgtg gatccggaag aggcgatccg
    14401 ctacgcggct cgcgtgctga tggaccagct gtccgtcttc gccgatctcg aaggcaccgc
    14461 gccggagcgg gtcgagaccg cctcgccgac catcgacccg gtgctgctgc gtccggtgga
    14521 cgatctggag ctcacggtgc gttcggccaa ttgcctgaag gccgagaaca tctattacat
    14581 cggtgacctg atccagcgca ccgagaccga gttgctgaag accccgaacc tgggccgcaa
    14641 gtcgctcaat gagatcaagg aagtgttggc ctcccgcggg ctgacgcttg gcatgaaact
    14701 ggaaaactgg ccgccggccg ggcttgaaaa gctcggttga atcgccgggc aagtgaggaa
    14761 ttgaaatgcg tcaccgtaac ggtcttcgca agctgaatcg taccagcagc caccgccagg
    14821 cgatgttccg caacatggcc aactcgctgc tgcaacacga agtcatcaag acgaccctgc
    14881 cgaaggcgaa ggaacttcgc cgcgtggtcg agccgatgat caccctgggc aagaagccca
    14941 gcgtcgccaa ccgtcgcctg gccttcaacc gcctgcgcga tcgcgacatg gtcgtcaagc
    15001 tcttcgacga gttggggccg cgctacgcca cccgcaacgg cggctacctg cgcatcctga
    15061 agtgcggttt ccgcgacggc gacaacgcgc cgatggccta cgtcgagctg ctcgaccgtc
    15121 cggacgtcga ggcggtggaa gtcgaggaag ccgaggccgc gtaaatagcg cgactcgcac
    15181 gaaagaccgg gcttatgccc ggtttttttt cgtacgtgcg tgctagcgtc gagcgtatcg
    15241 cgcgcaaggg cgcacaggac aggaggatgg aaggatggca gtgactctgg tgaccggcgg
    15301 tgcgggctac atcggctcgc acacctgcgt cgagcttctc ggcgccgggc aggacgtggt
    15361 ggtggtggat gacctctcca acgcatccta cgaggccgta cgtcggatcg aggaactcgg
    15421 tggcaagcgc cttgcggcct tcgtcgaggg cgatgtgcgc gacggcgcgg tgctcgcgcg
    15481 catctttgcc gaacacgagg tggcggcggt gattcatttt gccgccaaga aggcggtggg
    15541 cgagtcggtg tcgcagccgc tggcctacta cgacaacaac ctgcagggac tgctgtcggt
    15601 gctgcaggcc atggatgcgg ccggatgccg gcgcatggtg ttcagctcct cggcgacggt
    15661 gtacggcgat ccggcgtcgg tgccgatccg cgaggacttc ccgaccacgg cgaccaatcc
    15721 ctatggctgg accaagctca tgggcgagca gatcctgcgc gaccttgcgg cttcggacgc
    15781 gcgctggaac gtggtgctgc tgcgctactt caacccggtg ggcgcgcacg ccagcggccg
    15841 tatcggcgag gatcccgacg gcctgcccaa caacctgatg cccttcgtca gccaggttgc
    15901 ggtgggccgg ctgccgcgcc tgcgcgtgtt cggcgacgac tacccgacgc cggacggcac
    15961 cggggtgcgc gactacatcc acgtggtgga tctcgcgctc ggtcacctgc gcgcgctcga
    16021 gcgcatcggc gagctgcccg gcgtgaccac gctcaacctc ggcacggggc gtggctacag
    16081 cgtgctggag atggtgcgcg ccttcgaggc ggcgagcggc cggccggtgc ccttcgacat
    16141 cgtcgcgcgc aggccgggcg acatcgcagc gtgctgggcc gacccggcgc acgccgagcg
    16201 ggtgctgggg tggcgggcgc agcgcgactt gcaggcgatg tgcgaggatg cgtggcggtg
    16261 gcagagcggc aacccgcggg gctacgcaag cgcttgagcc gcacgcccgg ggttgggagc
    16321 gccggcgccg gggtgggcgc cggtcggcgg cccgcctgcc ttgggcctca gcccccgagc
    16381 accctgcgca ggtgacggcc ggtatggctc gccgggtgcg cggcgacctc ttcgggtgtg
    16441 ccgcagcaca ccacggtgcc gccgccgcca ccgccctccg gtcccatgtc gaccagccag
    16501 tcggcggtct tgatcacgtc gaggttgtgc tcgatcacca cgatggtgtt gccgtgctcg
    16561 cgcaggcgct gcagcaccgc gagcagcatc tcgatgtcct ggaagtgcag cccggtggtg
    16621 ggctcgtcga ggatgtacag ggtacgcccg gtgtcgcggc gcgagagctc gagggcgagc
    16681 ttcacgcgct gcgcctcgcc gcccgacagc gtcgtggcgc tctggccgag gcggatgtag
    16741 cccaggccca cgtccgtcag ggtctccagc ttgcgcgcga tggcggggac cgcggagaag
    16801 aagtccagcg cctgctccac cgtcatcccc agcacctcgt cgatcgtccg ccccttgtag
    16861 cggatctcca gggtctcgcg gttgtagcgg cggccgtggc agacgtcgca gggcacgtac
    16921 atgtcgggca ggaagtgcat ctcgaccttg accagaccgt cgccctggca ggcctcgcag
    16981 cgcccgccgc gcacgttgaa ggagaagcgc cccgggctgt agccgcgcgc gcgcgcctcg
    17041 ggcacgccgg cgaagagttc gcggatcggc gtcagcagcc cggtataggt cgccgggttg
    17101 gagcgcgggg tgcgtccgat cggcgactgg tccacgtcaa tcagcttgtc gaagtgctgc
    17161 aggccctcga tggcgtcgtg cggtgcgggt tcggtcgcgg cgccgttgag ccggtgcgcc
    17221 gcggcgcgcg ccagggtgtc gttgatcagt gtcgacttac ctgagcccga caccccggtg
    17281 atgcaggtga acagccccac gggcagcgcc acctccaccg ccttcaggtt gttgccgcgc
    17341 gcgccgacga tgcgcaggtg gcactccggg tcggggcgcg cgcggcgcgt cgggatggcg
    17401 atgcggcgcc ggccggccag gtaggcgccg gtcaccgagt gcggcgaggc gatgacctcg
    17461 tccggggtgc cgtgcgcgac cacctcgccg ccgtgctcgc ccgcacccgg ccccatgtcc
    17521 accagatagt cggcgctgcg gatggcgtcc tcgtcgtgct cgaccacgat caccgtgttg
    17581 ccgaggtcgc gcaggcgcgc cagcgttgcc agcaggcggt cgttgtcgcg ctggtgcagg
    17641 ccgatcgagg gctcgtcgag cacgtacatg acgccggtga ggcccgagcc gatctggctc
    17701 gcgaggcgga tgcgctgggc ctcgccaccc gagagggtgt cggcggagcg gtcgagcgag
    17761 aggtagtcca ggccgacgtc gatcaggaat ccgaggcgat cggcgatctc gcgcacgatg
    17821 cgctcggcca cctgggcgcg cgcgccggcg agctgcagcg tggcgaagaa gtcgcggcac
    17881 ccgccgagcg gcatgcgccc gacctcgtgc agcgcgcgcc ctccgaccag cacgtggcgc
    17941 gcctcgctgc gcagccgcgt gccatggcag gcagggcacg gccgggtggc gcggtacttc
    18001 gacagctcct cgcgcaccgc cacggcgtcg gtctcgcgca ggcggcgctc gaggttgggg
    18061 aggatgccct cgaagggatg ctccttgagc accatgcggc cgttgtcggc catgtagcgg
    18121 aaggcgatct tcgtccgccc cgagccgtcg agcacgatct cgcgcacgcg cgccggcagc
    18181 gcctcccagg gcgtctcgat gtcgaagccg tagtgcgccg ccaggctcgc cagcatctgg
    18241 aagtagaact ggttgcgccg gtcccagccg cggatcgccc ccgaagccag cgacagctcg
    18301 gggtgggcga ccacgcgcgc cggatcgaag aactcgacct cgcccagtcc gtcgcacttc
    18361 gggcaggcgc cggccgggtt gttgaaggag aacaggcgcg gctcgagctc ggcgagcgcg
    18421 aagccgcaca ccgggcaggc gaagcgcgcc gagaacaggt gctcgcgccc ggagtccatc
    18481 tcgaccgcga gcgcgcgccc gtcggcgtgg gtcagcgcgg tctcgaagga ctccgccagg
    18541 cggccgcgca ggtcggcgcg caccttgacg cggtcgatca ccacctcgac gttgtggcgg
    18601 cggcccttct ccagcgcggg cagggcgtcg agctccatca cctcgccgtc gacccgcacg
    18661 cgcacgaagc cctgcgcgcg caggtcggcg aagaggtcgc cctgctcgcc cttgcgcccg
    18721 gccaccacgg gggcgaggat catcagcttc gtgtcctcgg gcagggcgag cacgtggtcg
    18781 accatctgcg ccacgctctg cgcctcgagc gcgtgctgcg ggtggtcggg gcagtgcggc
    18841 gtgccggcgc gcgcgtagag caggcgcagg tagtcgtgga tctcggtgac cgtgccgacg
    18901 gtggagcgcg ggttgtggct ggtggccttc tgctcgatcg cgatcgccgg cgacaggccc
    18961 tcgatgagat cgacgtcggg cttctccatc agctgcagga actgccgcgc gtaggcggac
    19021 agcgactcga cgtagcggcg ctggccctcg gcgtacaggg tgtcgaaggc gagcgaggac
    19081 ttgcccgagc ccgacaggcc ggtgatcacc gtcagtcggt tgcgcggcag gtcgaggctg
    19141 acgttcctga ggttgtgcgt gcgggcgccg cggatgcgga tctggtccat ggctggatcg
    19201 ggggtgaaaa cgagctcccc aatatacgcc gggaagccgg tgtgaagcca aggcggtccg
    19261 cgcagatggt agaatcacgg tctttctcga agccggttct cccgtatgtc cgttcccgca
    19321 cgcgacgcca tgacgcgcga agaacgccgc gccggcatgg gcctggcggc gatcttcgcg
    19381 ctgcgcatgc tcggcctgtt cctgatcctg ccggtgttcg cggtgcacgc cgcgaccatt
    19441 cccggaggcg acgacctcac cctcgtgggc ctggcgatcg gtgcctatgg cctgacccag
    19501 gcctgcctgc agatcgccta cggcgccgcc tccgaccgct tcggccgcaa gccggtgatc
    19561 gtcttcggcc tcgtgctgtt cgtgctcggc agcgtggtcg cggcgatggc cgacggcatc
    19621 cacatgatca tcgtcggccg tgtgctgcag ggcgccgggg cgatctccgc cgcggtcacc
    19681 gcgctcgccg ccgacctcac ccgcgaccag caccgcacca aggtcatggc gatgatcggc
    19741 tcctcgatcg gcctcgtgtt cgcgctctcg atggtcgcgg cgccgttgct ctacgccgcg
    19801 gtcggcatgg acggcatctt ctggctcacg gccgtgctcg ccgccggcgc gatcggcgtg
    19861 ctgctgtggg cggtgccggt ggccccgccg gtgccgcgcg ccaccggccg gctgatcgac
    19921 gtgctgcgcg acggccagct catgcggctc aacttcggcg tgttcgcgct ccacctcatc
    19981 cagaccacga tgtgggtgat ggtgccctcg gccctggtcg ccggcggcgg cctgccgatg
    20041 cccgagcact ggaaggtcta cctgccggcg gtgttgctgt ccttcgtcgt catggtgccg
    20101 gcggtcatcg tcgccgagcg ccgcgacaag ctcaagccgg tgttcaacgc cgccatcgtg
    20161 ctgctcgcgc tcgtgcagat cgggctgtgg cttttcggtg acgggttgat accattggca
    20221 ttgttgctga cgctcttctt cgtcgccttc aacgtgctcg aggccaccca gccgtcgtgg
    20281 atctcgcgta tcgcgccgcc cggttccaag ggcacggcgc tcggcgttta caacaccctg
    20341 cagtcgatcg gcctgttcct cggcggcgtg ctcggcggct ggctgggcca gaccttcggc
    20401 cccgccgcgg tgagcctgtc gtgtgcggcg ctggcgctgc tctggctcgc gctggcgagc
    20461 acgatgaatc ccccgccgct acgcgcggca ccggctggcg cgccgcgctg agccgggctt
    20521 caccacactt accgccggcg cgcacgacgc ggccggcgac cgcatgcaaa ggagatccgg
    20581 atggcatccg tcaataaagt gatcctgatc ggcaacctcg gcgccgatcc ggaaagccgc
    20641 ttcgcccctt ccggcgatgc gatctgcaac atccgcctgg ccaccaccga gacctggcgc
    20701 gacaagaaca ccggcgagcg ccgcgaggcc acggaatggc accgcgtcgc cttcttcggc
    20761 aagctcgccg agatcgccgg ccagtacctg cgcaagggca gccaggtgta catcgagggc
    20821 agcctgcgca cgcgcaagtg gcaggaccag agcggccagg accgctacac caccgagatc
    20881 cgcgccgacg agatgaagat gctcggccgc cgcgagggcg gcgatgcgcc gatgcgcggc
    20941 ggcgagggcg gctgggatgc gggcggccag tccgccccgg cgcgccagcc cgcggccccg
    21001 gcgcagcgtc cgcagccgca gtcggcgccg ccgcagcagt ctggcggctt cggcgacttc
    21061 gacgacgaca ttccgttctg aagaagcccg ggagcgcccg cagcgctccg cggactgccg
    21121 ggcgggcgac gcgacgcgta cgctcgcccg tttcacatcg acaggcctgg cagcgaaccg
    21181 gccatcgggg aggaacaatg aaggacctga tccactacgg cgacggcgtg catgcgatcg
    21241 actccggcta cggccgcccg cagctcgccg ccatccacgt gatcgtgcag gacgggcgcg
    21301 ccgccgtcgt cgataccgcg agcaatgcct cggtgccgcg catcctcggc gcgctcgccg
    21361 cgctcggcat cgcccccgag gcggtggact gggtgttgct gacccacatc cacctcgacc
    21421 atgccggggg cgccggcagc ctgatgtgcg cgctgccgca ggcgaagctg ctcgtgcatc
    21481 cgcgcggcct gcgccacatg atcgacccga gcaagctttg ggaggccacc tgcgcggtgt
    21541 acggtcccga gcgcgcgttc gacctctacg gccagctcgt gccggtgccg gccgaacgca
    21601 tcgtgccggc caccgacggc ctcgagatcc atctgggtag ccgcatgctg cgggtgttgg
    21661 acacccccgg ccatgcccgc caccacatct gcatctggga ctcggtcgcg cgcgccttct
    21721 tcaccggcga caccttcggg ctgtcgtatc gagagctcga cgtcgacggc cgcgccttcg
    21781 tggtgccgac cacaacgccg acgcagttcg accccgaggg catgcacgcc tcgatcgacc
    21841 gcatgctggc gatgcgaccg caggcgatgt acctcacgca ctacagccgc gtggtcgacg
    21901 tcgaccgcct cggcgccgac ctgcaccgcc tgatcgacac catgctggca gtggccgagg
    21961 ccgctcgcgg cgacggcgcc gcccgccacg tcgagatcgt tgccggcctg gagcagatct
    22021 tccgtgagga ggccgcgcgc cagaactggg cgctcggcga ggacgagacg ctggaactgc
    22081 tgcgcatgga cctcgagctc aacgctcagg gcctcggcgt gtggctggac agccgccaga
    22141 ccagcgccgc cggtgcctga ttccgcgatg accgtcgcaa cgaccgaccg cgcgcgccgc
    22201 ttcggcggca tcgaccgtct ctacggtgcg ggcgcggccg cgcgtctcgc cggcgcgcac
    22261 gcctgcgtga tcggcatcgg tggcgtgggc tcgtgggctg ccgaggcgct cgcgcgcagc
    22321 ggggtggggc gcttgaccct gatcgacctc gatcacgtcg cagaatccaa catcaaccgc
    22381 caggcccatg cgctcgagga caccctgggc atggccaagg tgggcgccat ggcggcgcgc
    22441 atcgcgggta tcgacccgga ctgccgggtc acgaccatcg aggacttcct caccccggag
    22501 aacgccggtg cgctgctgca gggctacgac ctggtgatcg acgcgatcga caacgtgcgc
    22561 gccaaggtcg cgatcgcggt gacctgcacg cagcgccgca tcccgctggt gatggcgggt
    22621 ggggcgggcg gcaagcgcga ccccgcgcgc atcggcgccg acgacctcgc acgcacggag
    22681 caggacccgc tcctcgccaa ggtgcgcgcg cgcctgcgca aggagcacgg cttcccccgc
    22741 gaccccagga aaaaattcgg catcgaggcg gtgttctcca ccgaaccctt gcgctttccc
    22801 gaggtcgatg cctgcgacgc ggcccatccc ggcgccgcgt ccgcccccca ggggctggcg
    22861 tgcgccggct acggctcgag catggcggtg accgcgagcg tgggcctgct gtgcgcggcg
    22921 cgcgcactcg aacacctgct gcgccaggcc gaagcgcctg cgcgcggcgc caccccggag
    22981 ccctccgcat gaacgcagcc aatccgtccg catccgccct cgtcctcttc ggccacggcg
    23041 cccgcgaccc cgagtgggcc gggccgatgc ggcgcatccg cgaggcggcg ctcgcccgtc
    23101 cgggggcgcc acgcgtcgag ctcgccttcc tcgagttcat gactccgacc ctgcccgagg
    23161 cgatcgccgc gctcgccgcc gagggcgcgc gcaaagttgc ggtggtgccg atcttcctcg
    23221 cccagggcgg ccacctcaag cgcgacctgc cggtgttgct ggaggaggcg cgcgccgccc
    23281 accccggttg cgagatcacc ctggcgaccg ccgccggcga ggccgacccg gtggtggccg
    23341 cgatggcgga ctacgcgctc ggctgcctgg gctgagagcg tgagagtttt tctccaatct
    23401 ggccaggttg tgctgggact ggc
//
LOCUS       DAOTIN010000047        22665 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_2692_length_22665_cov_9.160460, whole genome shotgun sequence.
ACCESSION   DAOTIN010000047 DAOTIN010000000
VERSION     DAOTIN010000047.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 22665)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 22665)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22665
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2692_length_22665_cov_9.160460"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(141..1613)
                     /gene="trpE"
                     /locus_tag="P5537_08940"
     CDS             complement(141..1613)
                     /gene="trpE"
                     /locus_tag="P5537_08940"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HRV78206.1"
                     /translation="MLEHEFNALAAEGYNRIPLTLETFADLDTPLSIYLKLANEPYTY
                     LLESVQGGERFGRYSFIGLSSPTRIEVYGRSALLLTGNRLVERRDYGDPLNFVAEFMN
                     RIKVPPRQHLPRFAGGLVGCFGYDTVRYIEPKLAKTEKTDTLGTPDILLLLSEEVAIV
                     DNLSGKLTLVVYAEPEVPGAYKRAQKRLRELLARLREPVEIPEEFRGESAEPVSSFGE
                     EAFKDAVRRAKQYIVDGDLMQVVLSQRMSKPYAASPMALYRAIRSLNPSPYLFYFNLE
                     DFHVVGASPEILTRLEDDVVTVRPIAGTRKRGATPAEDLALEQELLADQKEIAEHVQL
                     LDLGRNDAGRVSEVGTVKVTERFTVERYSHVMHIVSNVEGKLRDGLDALAVLRATFPA
                     GTVSGAPKVRAMEIIDELEPVKRGIYAGAVGYLGFHGDMDLAIAIRTAVVKDGQIHVQ
                     AGAGIVADSDPDAEWNETQSKARAMLRAAEMAEGGLDTRF"
     gene            complement(1948..2634)
                     /locus_tag="P5537_08945"
     CDS             complement(1948..2634)
                     /locus_tag="P5537_08945"
                     /EC_number="3.1.3.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008967 - phosphoglycolate phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycolate phosphatase"
                     /protein_id="HRV78207.1"
                     /translation="MRGGARLALAPRAVLFDLDGTLLDTIADLADAANLMLAELARPA
                     RSVEEIHSFVGKGIPNLVRRCLTEGTHAGEDEIDRAVGVFRRHYALVNGVRTRIYPGV
                     VELLERLRGRGLPLAVVTNKAEAFTLPLLERMAIAHYFDAVVSGDTLPVKKPDPAMLH
                     LACERIGVPAGLALMVGDSANDAFAARDAGMPVLLVRYGYSEGMPVDSIECDGLLSTA
                     LEVLDHIGPA"
     gene            complement(2631..3326)
                     /gene="rpe"
                     /locus_tag="P5537_08950"
     CDS             complement(2631..3326)
                     /gene="rpe"
                     /locus_tag="P5537_08950"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002928586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HRV78208.1"
                     /translation="MYRIAPSLLSADFARLGEEVRDVIAAGADWIHFDVMDNHYVPNL
                     TIGPLVCEAIRPHTTAPIDVHLMVKPVDRIVPDFAKAGANVITFHPEASEHVDRTLGL
                     IRDAGCQAGLVFNPATPLDWMDHVMDKLDVVLLMSVNPGFGGQKFIPETLNKLRAARA
                     KLDAYEERSGRRILLEIDGGVKTDNIAEIARAGADTFVAGSAVFGAGKASDPHRYDSI
                     LGALRAELATVRA"
     gene            complement(3398..5743)
                     /locus_tag="P5537_08955"
     CDS             complement(3398..5743)
                     /locus_tag="P5537_08955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GspE/PulE family protein"
                     /protein_id="HRV78209.1"
                     /translation="MNPSVSSAVTHRLAFFKGLQTLTNRIHASKDTDEIMLELAPELC
                     SLFEAERFTIYALEEGGASIVTRVKTGLSGVQSIRLPIGENSIAGFVALSGQLVNIRD
                     VYDDDELRRISPHLELRREVDANTGFHSRQMLVAPIRDPDTGSLLGVVQLINTLNREP
                     FSKMAEEGLMGLAQTLGVAFLRHNRQSGRLRSRFEALVVDGRITAEEFADATREAREN
                     GAGTENVLIEQLGLSQAELGAAAARYFGMPYQPFVANHVKPMDLLRNIKREFVEKSLW
                     LPYEENPEGVVILCVDPEQVRSSGVAQNVLPKKRLTYRVTTKRDFEQTVEQFFGATLD
                     DASVSDLLSGLDDHEEDSLSLKDEVTAAADNELVKLVNKIIIDAYRQGASDIHIEPRA
                     GKEKTQIRFRKDGSLVPYIEIPASYRNPLVTRIKIMCDLDISERRKPQDGKIRFRKFA
                     PVDLELRVATLPTQGGMEDVVMRLLAHSEPIPIDQLGLLPFNLERLKNAIAKPYGIFF
                     VCGPTGSGKTTTLHSILSYINTPDTKIWTVEDPVEITQKGLRQVQVNRKAGIDFATMM
                     RAFLRADPDVIMVGEMRDHETVSVGIEASLTGHLVFSTLHTNSAPESVVRLLDMGMDP
                     FNFADALLGVLAQRLAKRLCLKCRVPYRAGEDELASLLDEYCEDMHLTPDFAADPRVA
                     RERVLGRWREAFGDKEGGFRLYRAVGCEHCNQGYKGRVGLHELMLGSDAIKRLIQSRG
                     RVDQILGQALAEGMRTLRQDGIEKVLSGITDMKQVRKVCVR"
     gene            complement(5828..6595)
                     /locus_tag="P5537_08960"
     CDS             complement(5828..6595)
                     /locus_tag="P5537_08960"
                     /EC_number="3.1.4.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004114 - 3',5'-cyclic-nucleotide
                     phosphodiesterase activity [Evidence IEA];
                     GO_function: GO:0008081 - phosphoric diester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3',5'-cyclic-nucleotide phosphodiesterase"
                     /protein_id="HRV78210.1"
                     /translation="MKLKVLGCSGGIGGAQPRTTSFLLDDDILIDCGTGVGDLTLDEL
                     ARIDHVFLTHAHLDHIAALPLMIDSVGELRQAPVQVHATPETIRILHSHIFNWLVWPD
                     FSAIPDHHQPFMRFQPLHVGERRDLGGRGITALPARHTVPAVAYRLDSGGGQLVFSGD
                     TAYCPELIAAINDCQQLRHLILETAFAEEQHGLAVASRHLCPSMARAVLDEIHGSPAI
                     HISHLKPGAGQRIIDQLEACAPGRRMRALGRGDILEF"
     gene            complement(6710..7456)
                     /locus_tag="P5537_08965"
     CDS             complement(6710..7456)
                     /locus_tag="P5537_08965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004344568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051219 - phosphoprotein binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FHA domain-containing protein"
                     /protein_id="HRV78211.1"
                     /translation="MPKLVLSMDGLVLKEMALVKERTTIGRKPDNDIQIDNLAISGHH
                     AVITCITNDAFLEDQNSTNGTYLNGQPVKKNVLRNNDVIELGKYRIKYILDDAKPGLA
                     PSEMIETAAYKAFEMPRATTETVLPPGAPAPSDTQILSAAARQAGAAAAAATAASAGG
                     EGQGVIQVLSGGNAGRELLLTKSLTTLGKPGRQVAVITRRPHGYFITHVEGASFPLVN
                     GSAIDAQARPLRDHDIIEIAGVKMEFFLRA"
     gene            complement(7603..8496)
                     /gene="sucD"
                     /locus_tag="P5537_08970"
     CDS             complement(7603..8496)
                     /gene="sucD"
                     /locus_tag="P5537_08970"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015434419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate--CoA ligase subunit alpha"
                     /protein_id="HRV78212.1"
                     /translation="MSILINKDTKVITQGITGKTGQFHTEKCIEYANGKNCFVAGVNP
                     KKAGEKILDVPIYGSVKDAKDATGATVSVIYVPPAGAAAAIWEACEADLDLAICITEG
                     IPVRDMLVVRNKMKQKVAAGGKETLLLGPNCPGLITPDEIKIGIMPGHIHRKGRIGVV
                     SRSGTLTYEAVAQLTEIGLGQSSAVGIGGDPINGLKHIDVMRMFNDDPDTDAVIMIGE
                     IGGPDEAEAAQWCKANMKKPIVGFIAGVTAPAGKRMGHAGALISGGADTADAKLAIME
                     ECGFKVTRNPSEMAKLLKAML"
     gene            complement(8509..9669)
                     /gene="sucC"
                     /locus_tag="P5537_08975"
     CDS             complement(8509..9669)
                     /gene="sucC"
                     /locus_tag="P5537_08975"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011289089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-forming succinate--CoA ligase subunit beta"
                     /protein_id="HRV78213.1"
                     /translation="MKIHEYQAKELLRKYGVVTPRGFHCVSVDAAVKAAEELGGKIWV
                     VKAQIHAGGRGKGGGVKLARSLDEVRQHANDILGMQLVTHQTGPEGQKVRNLLIEEGA
                     DIKHEYYVAALTDRATQTVAMMASSEGGMDIEEVAHSTPEKIIKVFVDPLVGLTDAQA
                     TDLAKGIGVPEGSVAKAVDAFKKLYTCYMETDASLAEINPLILEGNGNIKALDAKFNF
                     DSNALYRHPEIVDFRDFDEEDADEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTI
                     KLFGAEPANFLDVGGGATTEKVTEAFKIMLKNPKVKGILVNIFGGIMRCDTIATGVVA
                     AAKEVHLSVPLVVRMKGTNEDLGKKILADSGLPIITADTMAEAATKIVAAVK"
     gene            10077..11891
                     /locus_tag="P5537_08980"
     CDS             10077..11891
                     /locus_tag="P5537_08980"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78214.1"
                     /translation="MNNNNLPLAIALAAAFLGASPQAAAAALGEVAALSAMGESFRAE
                     IRLPGATRSDAECYRVVSVPGGEFPTLQQARFDVAGTGANARLVVRDAARVGEPVLRL
                     IIENVCESRLRREYTLLMPFGPSAQRPATAAAPAATPRPAARAPATRPAPPARPASKP
                     RARTLSTTGGESLLTLAESLYPDDDRARARFIEATAAANPKLFADIAALTRVLPAGTT
                     LRMPDLRAQRSATRSPPPEVTPAPAAQGPDRLVVDKALATRGPGTSTPATTASDGPRS
                     HAERERALAAAIDRSIIAEMELLARIKELEEIQAALKERVLAMQAKAPPPAAAAIAVA
                     AAPPPPPPPVAEAAAEATPAAVDREAGWKSDGYLFAGLGLAALAVVALLRRSRRPARL
                     AAPSRPADTATATALGNAEPRKGRARAEDAGFGFGIGTVDTRLEWPAGTETEVIQEHK
                     SAVELADIMMSFGRVRGAAETLAEFIRGNPREAVTPWLKLLEVYRAAGLRDEFNAIAG
                     ELNKTFNVTTVNWQSYDALRASKMSLEDLPHICESLQKTWRTTACQRYLQQLLRDNRN
                     GTRAGFPFSVIDEILTLTAILEEDLGPCPPAGSASTQR"
     gene            complement(11888..12637)
                     /locus_tag="P5537_08985"
     CDS             complement(11888..12637)
                     /locus_tag="P5537_08985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HRV78215.1"
                     /translation="MQLTELGDHLDTLLDAPRLKDYCPNGLQVEGRPEVLRVLCGVTA
                     SQALLDLAVAGGHDAVFVHHGLFWKGDDGRVTGFRRRRLRTLLANDISLFAYHLPLDV
                     HAEFGNNAQLACLMGWQGEARFADQELGWIGRPEEEGQSAQEIARALAARLGREPMLV
                     GDGERRVRRIAWCTGAAQGFFEQAILAGADLYVSGEISEPTVHLARESGVPYIAAGHH
                     ATERYGARAIAHYLNEVLGLEARFVDLDNPV"
     gene            12742..13893
                     /locus_tag="P5537_08990"
     CDS             12742..13893
                     /locus_tag="P5537_08990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HRV78216.1"
                     /translation="MRRLWLIFAQAVTVSVAVLFVLNTLKPEWLRQATPAAVVAILEA
                     PAGAEQAPAVGSYAPAAQRSMPAVVHIFTTKGGRGQRHPLLDDPLFRHFFGERPDSAP
                     SESGLGSGVIVSPDGYVLTNNHVIETADAIEVALNDGRKFAARLVGRDPETDLAVLRI
                     DGADVLPAITFPAADSLAVGDVVLAIGNPFGVGQTVTMGIVSALGRSQLGINTFENYI
                     QTDAAINPGNSGGALVDSAGSLVGINTAIYSRSGGSLGIGFAIPVSIARDVLEQIVAT
                     GEVVRGWVGVEIQDLTPELAASFGYRDASGALIAGVLRGSPADRAGVRPGDVLVALDG
                     ETVRDPRAMLDMVAALPPGKRAAFRVRRGAEELDLDVEVGRRPVPQGAR"
     gene            complement(13922..14719)
                     /gene="tatC"
                     /locus_tag="P5537_08995"
     CDS             complement(13922..14719)
                     /gene="tatC"
                     /locus_tag="P5537_08995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocase subunit TatC"
                     /protein_id="HRV78217.1"
                     /translation="MSEQQETFIAHLVELRDRLIRALLAIVIVFVCLMPWAGAIYDIL
                     AKPMMDTLPAGTNMIATGVVTPFFVPVKVTMMVAFVLALPWVLYQAWAFIAPGLYAHE
                     KRLALPLVLGSTLLFLLGMAFCYFFVFGTVFKFIAEFAPKSIVPAPDIEQYLSFVMSM
                     FIAFGITFEVPVAVILMVKAGIVDVAKLRESRPYVIVGAFVVAAIVTPPDVVSQFMLA
                     VPMCLLYELGILLAGMLSKPSPRQEAADEAVQQLAAPSVAEGEGERR"
     gene            complement(14716..15231)
                     /gene="tatB"
                     /locus_tag="P5537_09000"
     CDS             complement(14716..15231)
                     /gene="tatB"
                     /locus_tag="P5537_09000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase protein
                     TatB"
                     /protein_id="HRV78218.1"
                     /translation="MFDFGFSELVVIGVVMLIVVGPERLPKVARTAGHLLGRVQRYVS
                     DVKSDIQREMQLEELKKLQEQVRHQAQELEASVRTGVAGVESGIGDTVAEVRSILPES
                     PVSASAVAPAGAGAPSPAATPANSPAAAPVSVGNPPATPAAGVAVPTPQLELGLDSVP
                     RTAAGADKVKA"
     gene            complement(15327..15563)
                     /gene="tatA"
                     /locus_tag="P5537_09005"
     CDS             complement(15327..15563)
                     /gene="tatA"
                     /locus_tag="P5537_09005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0043953 - protein transport by the Tat
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatA"
                     /protein_id="HRV78219.1"
                     /translation="MGSFSIWHWLIVLVIILLVFGTKKLRNIGSDLGGAVKGFKEGMK
                     EGDSAGAGDASQQKLSQGQTIEGEAREKVDQNRS"
     gene            complement(15574..15921)
                     /locus_tag="P5537_09010"
     CDS             complement(15574..15921)
                     /locus_tag="P5537_09010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004307334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HRV78220.1"
                     /translation="MSDCVFCRIVRGEIPSKKVYEDEHVYAFHDIHPVAPVHVLVVPK
                     VHVDSMAQLSGEHEAAMGRLMVAAGRIAREQGCTDGFRTIVNTGRVGLQEVYHLHLHI
                     LGGPDPLPPMLKR"
     gene            complement(15918..16256)
                     /locus_tag="P5537_09015"
     CDS             complement(15918..16256)
                     /locus_tag="P5537_09015"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004307336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004636 - phosphoribosyl-ATP diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-ATP diphosphatase"
                     /protein_id="HRV78221.1"
                     /translation="MIDIEVLHRVSETLAARKKADPDSSYVSSLYQKGTDTICKKVAE
                     EAAETIMAAKDKDMLHLVWEVTDLWFHSMVLLAHHGLSVDDVLAEFRRREGVSGIDEK
                     KSRSAEGARA"
     gene            complement(16253..16648)
                     /gene="hisI"
                     /locus_tag="P5537_09020"
     CDS             complement(16253..16648)
                     /gene="hisI"
                     /locus_tag="P5537_09020"
                     /EC_number="3.5.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002928556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004635 - phosphoribosyl-AMP
                     cyclohydrolase activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="HRV78222.1"
                     /translation="MSTNTRWLNEIKWDEHGLVPVIAQEASSGDVLMFAWMNREALQR
                     TAETGEAIYWSRSRRKLWHKGEESGHVQKVLDMRIDCDNDVVLLRIEQVGGIACHTGR
                     HSCFFQKYFADGRWEAVEPVLKDPQEIYK"
     gene            complement(16645..17403)
                     /gene="hisF"
                     /locus_tag="P5537_09025"
     CDS             complement(16645..17403)
                     /gene="hisF"
                     /locus_tag="P5537_09025"
                     /EC_number="4.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015434407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HRV78223.1"
                     /translation="MLAKRIIPCLDVKSGRVVKGVNFVELRDAGDPVEIARRYDEQGA
                     DEITFLDITASSDDRDIILHVVEQVAEQVFIPLTVGGGVRVVEDVRRLLNAGADKVSM
                     NTAAVNNPQLVHDASSKVGSQCIVVAIDAKQTAPGKWEVFTHGGRNNTGLDAIEWARK
                     VESLGAGEILLTSMDRDGTKSGFDLALTRAVSDAVRIPVIASGGVGTLEHLAEGVSEG
                     RADAVLAASIFHFGQHTVREAKELMRARGIEVRL"
     gene            complement(17426..18175)
                     /gene="hisA"
                     /locus_tag="P5537_09030"
     CDS             complement(17426..18175)
                     /gene="hisA"
                     /locus_tag="P5537_09030"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003949 -
                     1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HRV78224.1"
                     /translation="MLLIPAIDLKDGQCVRLKQGEMDDATVFSSDPGAMARHWLEAGA
                     RRLHLVDLNGAFAGKPKNGAAIRAITDVVGDDIPVQLGGGIRDLDTIEHYLDNGISYV
                     IIGTAAVKNPGFLHDACSAFPGHIIVGLDAKDGKVAVDGWSKLTGHDVVDLAKKFEDY
                     GVESVIYTDIGRDGMLSGVNIEATVRLARALRIPVIASGGITDLRDIDGLCAVEDEGI
                     MGAITGRAIYEGTLDFAAAQARADELSGTSE"
     gene            complement(18220..18858)
                     /gene="hisH"
                     /locus_tag="P5537_09035"
     CDS             complement(18220..18858)
                     /gene="hisH"
                     /locus_tag="P5537_09035"
                     /EC_number="4.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004307344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HRV78225.1"
                     /translation="MTSVAIIDYGMGNLRSVAKAIEHVAPGHDVFVTSDSARVAAAER
                     VVFPGQGAMPDCMRELDARGLRPAVLAAAAEKPFLGICIGQQMLFQHSAEGDVPGLGI
                     LPGEVVRFPEAKMVAADGSRLKVPHMGWNEVRQCGAHPMWEGIPDGERFYFVHSYFVV
                     PADAALTAAETDYGVRFTSAVARANIFAAQFHPEKSAAAGLRLLANFIRWQP"
     gene            complement(18920..19507)
                     /gene="hisB"
                     /locus_tag="P5537_09040"
     CDS             complement(18920..19507)
                     /gene="hisB"
                     /locus_tag="P5537_09040"
                     /EC_number="4.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011236547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004424 - imidazoleglycerol-phosphate
                     dehydratase activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HRV78226.1"
                     /translation="MRQAEVTRNTLETKISVRIDLDGSGQGRLETGVPFFDHMLDQIV
                     RHGLIDLDIHCEGDTHIDDHHTVEDVGITLGQAFAKALGDKKGLRRYGHAYVPLDEAL
                     SRVVVDFSGRPGLHYFVNYTRARIGNFDVDLAREFFQGFVNHAGVTLHIDNLRGDNAH
                     HQCETVFKAFARALRMAAEHDERAAGTIPSTKGAL"
     gene            19691..20764
                     /gene="hisC"
                     /locus_tag="P5537_09045"
     CDS             19691..20764
                     /gene="hisC"
                     /locus_tag="P5537_09045"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004307348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HRV78227.1"
                     /translation="MSRFWSAVVHGLTPYVPGEQPKLDNLVKLNTNEHPCGPSPKVLE
                     AIRAATGDGLRLYPDPNADALKAALARHHGVRPEQIFVGNGSDEVLAHAFMALLKHER
                     ALWFPDITYSFYPVYCGLYDIEPRIVPLAEDFSIRVEDYLPRGDERAGAIIFPNPNAP
                     TGRLLALPEVERIVSANPDAVVLVDEAYVDFGGDSAIALVDRHPNLLVTRTFSKSRSL
                     AGLRVGYAVGDAALVEALERIKNSFNSYPLDRLAIAGAVASVEDEDYFRASCAQVVAT
                     RERLVAELQALGFEVLPSAANFIFARHPARDGAELTAALRKRAIIVRHFKAARIDQFM
                     RITVGTDAQCAVLVTALREILGG"
     gene            complement(20771..21592)
                     /locus_tag="P5537_09050"
     CDS             complement(20771..21592)
                     /locus_tag="P5537_09050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004307351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HRV78228.1"
                     /translation="MSGGWGGRAWVLGVYAFLYVPILCLIVFSFTAGEITTRLDGLSL
                     RWYAALARDVELHAAVLLSLRVGALAATAAVVVGTAAAVILVRAGDYPGSRFFLGMMS
                     APMVMPEVVVGLSLVLLFTHPALAILGGRGVAAIWVAHTTLCTAYVAVLVASRLREMD
                     RALEEAALDLGCPPLKVFFVITVPVIAPALAAGWLLAFTLSMDDFVLAAMLSDPGSTT
                     LPVLVFARLHHGLKPEINALATVIVVVVSIAVLLANRLLLGPPRAAAQPSAARGG"
     gene            complement(21589..22533)
                     /locus_tag="P5537_09055"
     CDS             complement(21589..22533)
                     /locus_tag="P5537_09055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004307352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HRV78229.1"
                     /translation="MRAHPASAQGYGRFWVGLLPWAWMLFFFVLPFALIVNVSLSTPD
                     LAVPPYVSPFAGTTADGAPAFRPDPASYARLGDELAALATPGADRPYLAAYANSVLLA
                     ALTTLCCLLLGYPFAYRLARAPEVMRNTLLMLVMLPFWTSFLLRVYAWMGLLDSSETG
                     LINQALLGLGVVAEPLPLLYNTGAVLVGMVYSYLPFMVLPLYANLVKLDLRLLEAARD
                     LGARPATVFLRVTLPLSLRGIVAGSMLVFIPAVGEFVIPDLLGGGSVMTIGRSIWDDF
                     GPNQDWPMAAAVAVVMVVMLIAPIVLLHRHGRRAGRGA"
     gene            complement(22530..22658)
                     /locus_tag="P5537_09060"
     CDS             complement(22530..22658)
                     /locus_tag="P5537_09060"
                     /inference="COORDINATES: protein motif:HMM:NF019998.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TOBE domain-containing protein"
                     /protein_id="HRV78230.1"
                     /translation="MPGGRAMIASVPAAHWGETAPPARGEPVRVSWPAPDGVLLLR"
BASE COUNT         3543 a         7704 c         7880 g         3538 t
ORIGIN      
        1 gtactgcacg aggttgtagg tgaagctgtc gtagttgtcg atcatcagca gcatggtctt
       61 tcccttcgcg aagccgcgcg ctgcgggctc cgccagtatc gaggcgtggt gggcggaggg
      121 cggcgcgggc gccgccgcgc tcagaagcgg gtgtcgagcc cgccttcggc catctcggcg
      181 gcgcgcagca tcgcgcgcgc cttgctctgg gtctcgttcc actcggcgtc ggggtcggag
      241 tcggcgacga tgccggcgcc ggcctggacg tggatctggc cgtccttgac caccgcggta
      301 cggatcgcga tcgccaggtc catgtcgcca tgaaagccga ggtagcccac cgcgccggcg
      361 tagatgccgc gcttgaccgg ctcgagctcg tcgatgatct ccatcgcgcg caccttgggc
      421 gcgcccgaca cggtgccggc cgggaaggtg gcacgcagca ccgcgagcgc gtcgagcccg
      481 tcgcgcagct tgccctcgac gttggagacg atgtgcatca cgtgcgagta gcgctcgacg
      541 gtgaagcgct cggtgacctt gaccgtgccg acctcggaga cgcgaccggc gtcgttgcgg
      601 ccgaggtcga gcagctgcac gtgctcggcg atctccttct ggtcggcgag gagttcctgc
      661 tcgagcgcga ggtcctctgc cggcgtggcg ccgcgcttgc gggtgccggc gatcgggcgc
      721 acggtgacga cgtcgtcctc gagccgggtg aggatctccg gcgaggcgcc gacgacgtga
      781 aagtcctcga ggttgaagta gaacaggtag ggcgaggggt tgagcgagcg gatcgcgcgg
      841 tacagcgcca tcgggctggc cgcgtagggc ttgctcatgc gctgcgacag cacgacctgc
      901 atcagatcgc cgtcgacgat gtactgcttg gcgcggcgca ccgcgtcctt gaaggcctcc
      961 tcgccgaagc tcgacaccgg ctcggcggac tcgccgcgga actcctcggg gatctccacc
     1021 ggctcgcgca ggcgggcgag cagttcgcgc aggcgcttct gcgcgcgctt gtatgcgccc
     1081 ggcacctcgg gctcggcata gacgacgagg gtgagcttgc cgctgaggtt gtcgacgatg
     1141 gcgacctctt cggacaacag cagcaggatg tcgggcgtgc cgagcgtgtc ggtcttctcg
     1201 gtcttcgcca gcttgggctc gatgtagcgc accgtgtcgt agccgaagca gccgaccagg
     1261 ccgccggcga agcgcggcag gtgctggcgc ggcggcacct tgatgcggtt catgaactcg
     1321 gcgacgaagt tgagcgggtc gccgtagtcg cggcgctcga ccaggcggtt gccggtgagc
     1381 agcagggccg agcggccata gacctcgatg cgggtcggcg aggacaggcc gatgaaggag
     1441 tagcgcccga agcgctcgcc gccctgcacc gactcgagca ggtaggtgta gggctcgttg
     1501 gcgagcttca ggtagatgga gagcggggtg tcgagatcgg cgaaggtctc gagggtgagc
     1561 gggatgcggt tgtagccctc ggcggcgagg gcgttgaatt cgtgttcgag catgggggct
     1621 ccacgtggga cgggtcgatc ggagaggctt gcagcgggcg gggaatgcgg cgcgcgacgt
     1681 gcgcggcggg ccccgcaggg ggaggtcgcg ttcagtggcc caaaggccaa cgccagccac
     1741 cgcgccagtc gggctgggcg gaggacgagg cggcgaacag gcgatcccgg gttgcgagca
     1801 tcacgatgac tgtcgttggt ggaggaacga acgagggcgg acgaagggct caggagctac
     1861 gcccggcaaa gccgcacaca caaactgcag acccgcagca gatcgcgact tcgcaccgca
     1921 tcgcgcactc ccgcggtcta cgtgcaccta tgcaggaccg atatggtcca gcacttcgag
     1981 tgcggtcgat agtagcccat cgcattcgat gctgtccacc ggcatgccct cgctgtaacc
     2041 gtagcgcacc agcagcaccg gcatgccggc gtcgcgcgcg gcgaaggcgt cgttggccga
     2101 gtcgcccacc atcagcgcca gccccgccgg cacgccgatg cgctcgcagg ccaggtgcag
     2161 catcgccggg tcgggtttct tgaccggcag ggtgtcgccg ctgaccacgg cgtcgaagta
     2221 atgtgcgatc gccatgcgct cgagcagcgg cagcgtgaag gcctcggcct tgttggtgac
     2281 caccgcgagc ggcaggccgc gtccgcgcag gcgctcgagc agctcgacga cgccggggta
     2341 gatgcgcgtg cgcaccccgt tgaccagggc gtagtggcgg cggaacacgc ccacggccct
     2401 gtcgatctcg tcctcgccgg cgtgcgtgcc ctcggtgagg cagcgccgca cgaggttggg
     2461 aatgcccttg ccgacgaagc tgtggatctc ctccacgctg cgtgccgggc gggcaagctc
     2521 ggcgagcatg aggttggcgg cgtcggcgag gtcggcgatg gtgtcgagca gggtgccgtc
     2581 gaggtcgaac agcaccgcgc gcggcgccag cgccaggcgt gcgccccccc tcatgcccgc
     2641 accgtggcca gctcggcgcg cagcgcgccc aggatcgagt cgtagcggtg cggatcggag
     2701 gccttgccgg cgccgaacac cgcggagccg gcgacgaagg tgtccgcgcc ggcgcgggcg
     2761 atctcggcga tgttgtcggt cttcaccccg ccgtcgatct cgagcaggat gcggcggccg
     2821 ctgcgttcct cgtaggcgtc cagcttcgca cgcgcggcac gcagcttgtt cagggtctcg
     2881 ggaatgaact tctgcccgcc gaagcccggg ttgacgctca tcagcagcac gacgtcgagc
     2941 ttgtccatga cgtggtccat ccagtcgagc ggggtggcgg ggttgaacac cagcccggcc
     3001 tggcagccgg cgtcgcggat cagcccgagc gtgcggtcga catgctcgga ggcctcgggg
     3061 tggaaggtga tgacgttggc gccggccttg gcgaagtcgg ggacgatgcg atcgaccggc
     3121 ttcaccatca ggtgcacgtc gatcggcgcc gtggtgtgcg ggcggatggc ctcgcacacc
     3181 agcggaccga tggtgaggtt ggggacgtaa tggttgtcca tgacgtcgaa gtggatccag
     3241 tcggcgccgg cggcgatgac gtcgcggacc tcctcgccga ggcgggcaaa atcggcggac
     3301 agcaggctgg gggcgatgcg gtacatggtg gtctccgatg caggttgctg cccggattct
     3361 aacccgggcc ccccacggtc ggccgccccc gccccgctca gcgcacgcag accttgcgca
     3421 cctgcttcat gtcggtgatg ccggagagca ccttctcgat gccgtcctgg cgcagcgtgc
     3481 gcatgccctc ggcgagcgcc tggccgagga tctggtcgac gcgaccgcgc gactggatca
     3541 ggcgcttgat cgcgtccgag ccgagcatca gctcgtgcag gccgacacgg cccttgtagc
     3601 cctggttgca gtgctcgcag ccgaccgcac ggtagagccg gaagccgccc tccttgtcgc
     3661 cgaaggcctc gcgccagcgc ccgagaacgc gctcgcgcgc gaccctgggg tcggcggcga
     3721 agtccggggt caggtgcatg tcctcgcagt actcgtcgag caggctggcg agctcgtcct
     3781 cgccggcacg gtaaggcacg cggcacttca ggcacaggcg cttggccagg cgctgggcga
     3841 gcacgccgag cagcgcgtcg gcgaagttga acgggtccat gcccatgtcg agcagacgga
     3901 cgacggactc cggcgcgctg ttggtgtgca gggtcgagaa cacgaggtgg ccggtcagcg
     3961 aggcctcgat gccgaccgag acggtctcgt ggtcgcgcat ctcgcccacc atgatcacgt
     4021 cggggtcggc gcgcaggaag gcgcgcatca tggtggcgaa gtcgatgccg gccttgcggt
     4081 tgacctgcac ctggcgcaag cccttctggg tgatctcgac cgggtcctcg accgtccaga
     4141 tcttggtgtc gggggtgttg atgtagctca ggatggagtg cagcgtggtg gtcttgcccg
     4201 agccggtggg gccgcacacg aagaagatgc cgtagggctt ggcgatcgcg ttcttgaggc
     4261 gctcgaggtt gaagggcaac aggccgagct ggtcgatcgg gatcggctcg ctgtgggcga
     4321 gcaggcgcat gaccacgtct tccatgccac cctgggtggg cagcgtggcc acgcgcagct
     4381 cgaggtcgac cggcgcgaac ttgcggaagc ggatcttgcc gtcctgcggc ttgcggcgct
     4441 cggagatgtc gaggtcgcac atgatcttga tgcgggtgac gagcgggttg cggtagctcg
     4501 ccgggatctc gatgtagggc accagcgagc cgtccttgcg gaagcggatc tgcgtcttct
     4561 ccttgccggc gcgaggctcg atgtggatgt cggaggcgcc ctggcgatag gcgtcgatga
     4621 tgatcttgtt gaccagcttg acgagctcgt tgtcggcggc ggcggtgacc tcgtccttga
     4681 gcgagagcga gtcttcctcg tggtcgtcga gccccgacag cagatcggag accgaagcgt
     4741 cgtccagggt cgcaccgaag aactgctcga ccgtctgctc gaagtcgcgc ttggtcgtga
     4801 cccggtaggt gaggcgcttt ttcggcagca cgttctgcgc cacgcccgag ctgcgcacct
     4861 gctcggggtc gacgcacagg atcaccacgc cctcggggtt ctcctcgtag ggcagccaca
     4921 ggctcttctc gacgaactcg cgcttgatgt tgcgcagcag gtccatcggc ttgacgtggt
     4981 tggcgacgaa gggctggtag ggcatgccga agtagcgcgc cgccgcagcg ccgagttccg
     5041 cctggctcag gccgagctgc tcgatcagga cattttcggt acccgcgccg ttctcgcgcg
     5101 cctcgcgggt ggcgtcggcg aactcctcgg cggtgatgcg accatcgacc accagcgcct
     5161 cgaaacgcga acgcagccgc ccgctctggc ggttgtggcg caggaaggcg acgccgagcg
     5221 tctgcgccag ccccatcagg ccctcctcgg ccatcttgga gaagggctcg cggttgagcg
     5281 tgttgatgag ctgcacgacc ccgagcaggc tgccggtgtc cggatcgcgg atcggcgcca
     5341 cgagcatctg ccgcgaatgg aagccggtgt tggcgtcgac ctcgcggcgc agctcgaggt
     5401 gtggcgagat gcgccgcagc tcatcatcgt cgtagacgtc acggatattg accagctggc
     5461 cgctgagcgc gacgaatccg gcgatgctgt tctcgccgat cggcaggcgg atgctctgca
     5521 ccccgctcag cccggtcttg acccgggtga cgatggaggc gccgccctcc tcgagcgcgt
     5581 agatcgtgaa gcgctcggcc tcgaacagcg agcacagctc gggcgcgagc tcgagcatga
     5641 tctcgtcggt gtccttgctc gcatggatgc gattggtcag cgtctgcaag cccttgaaga
     5701 aggcgagacg gtgcgtgacg gcactggaca cggatgggtt cattggcatg gctccggctg
     5761 gaagcgcgcc cggggacgag cgccagcgtt cagggtggca gggtccgcaa cgcgctcggt
     5821 gcccgcatca gaactccagg atgtcgccac gaccgagcgc acgcatcctg cgcccgggtg
     5881 cgcaggcctc gagctggtcg atgatgcgct gccccgcgcc cggcttgagg tggctgatgt
     5941 ggatcgccgg ggagccgtgg atctcgtcga gcaccgcacg cgccatgctc gggcagaggt
     6001 gacgcgaggc caccgcgagt ccgtgctgct cctcggcgaa ggccgtctcg aggatcaggt
     6061 ggcgcagctg ctggcagtcg ttgatcgccg cgatgagttc gggacagtat gcggtatccc
     6121 cggaaaacac cagctgcccg cccccgctgt cgagccggta ggccaccgcc ggcacggtat
     6181 ggcgcgccgg cagcgcggtg atgccgcgcc cgcccaggtc ccggcgctcg ccgacgtgga
     6241 gcggctggaa gcgcatgaag ggctggtggt ggtcggggat cgcggagaag tcgggccaca
     6301 ccagccagtt gaagatgtgc gagtgcagga tgcggatggt ctcgggcgtc gcatgcacct
     6361 gcaccggcgc ctggcgcagc tcgcccaccg agtcgatcat cagcggcagc gcggcgatgt
     6421 ggtcgaggtg cgcatgggtg aggaagacgt ggtcgatccg cgccaactcg tccagcgtga
     6481 ggtcgccgac ccccgtcccg cagtcgatca gtatgtcgtc gtcgagcagg aacgaggtcg
     6541 tgcgcggctg cgccccgccg atcccgccgc tgcaccccag caccttgagc ttcatggcct
     6601 ccgtcatccg cgtccgcggc agccggaggc caccgtgtga acccatgcga aacattagca
     6661 tcgcacgccc cgtggccgcg cgggagaaag tcacgcccgt cccgcccgct caggcgcgca
     6721 ggaagaactc catcttgacg cctgcgatct cgatgatgtc gtggtcgcgc agggggcgcg
     6781 cctgcgcgtc gatcgcgctg ccattgacga gcgggaagct cgcgccctcg acgtgggtga
     6841 tgaagtagcc gtggggtcgg cgcgtgatga ccgcaacctg tcgccccggc ttgcccagcg
     6901 tggtgagcga cttggtaagc aacagctctc gcccggcgtt gccgccgctg agcacctgga
     6961 tcacaccctg cccctcgccg cctgcggagg cggcggttgc ggccgcggcg gcggcgccgg
     7021 cctggcgtgc cgcagcggag aggatctgcg tgtcgctcgg agccggcgca cccggcggca
     7081 gcacggtctc ggtcgtggcg cgcggcatct cgaaggcctt gtaggcggca gtctcgatca
     7141 tctcggacgg cgccagcccc ggcttggcgt catccaggat gtacttgatg cggtacttgc
     7201 cgagctcgat gacgtcgttg ttgcgcagca cgttcttctt gaccggctgg ccgttgaggt
     7261 aggtgccgtt ggtgctgttc tggtcctcga ggaaggcgtc gttggtgatg caggtgatca
     7321 ccgcgtgatg gccgctgatc gcgagattgt cgatctggat gtcgttgtcc ggcttgcgcc
     7381 cgatcgtggt gcgctccttg acgagcgcca tctccttgag caccagcccg tccatgctga
     7441 gaaccaactt cggcatgccc atacccgtgt gtaagtggaa cgaccggcgc gcccgcgccg
     7501 cctgcgagga atccgtcgcc cattctagcg cgcgcaccgc gccggttaac aaaaaagggc
     7561 gccggaagat ccggcgcccc tgcatatgcc ccgagggacg gcttacagca tcgccttgag
     7621 cagcttggcc atctcggacg ggttgcgcgt caccttgaag ccgcactctt ccatgatggc
     7681 gagcttggcg tcggcggtgt cggcgccgcc ggagatcagc gcaccggcgt ggcccatgcg
     7741 cttgccggcc ggcgcggtga cgccggcgat gaagccgacg atcggcttct tcatgttggc
     7801 cttgcaccac tgcgcggctt cggcttcgtc aggaccgccg atctcgccga tcatgatcac
     7861 cgcgtcggtg tccggatcgt cgttgaacat gcgcatcacg tcgatgtgct tgaggccgtt
     7921 gatcgggtcg ccgccgatgc cgaccgccga ggactggccg aggccgatct cggtgagctg
     7981 ggcgacggct tcataggtca gcgtgccgga gcgcgagacc acgccgatgc ggcccttgcg
     8041 gtggatgtgg ccgggcatga tgccgatctt gatctcgtcg ggcgtgatca ggccggggca
     8101 gttggggccg agcagcaggg tttccttgcc gccggcggcg accttctgct tcatcttgtt
     8161 gcgcacgacc agcatgtcgc ggaccgggat gccctcggtg atgcagatcg ccagatcgag
     8221 atcggcctcg caggcctccc agatcgcggc agccgcgccg gcgggcggca cgtaaatcac
     8281 cgagacggtg gcgccggtgg cgtccttggc gtccttgacc gagccgtaga tgggcacgtc
     8341 gaggatcttc tcgccggcct tcttcgggtt cacgccggcg acgaagcagt tcttgccgtt
     8401 ggcgtactcg atgcacttct cggtgtggaa ctggccggtc ttgccggtga tgccctgggt
     8461 gatgaccttg gtgtctttgt tgatcaggat ggacattcga agctctcctt acttgaccgc
     8521 agcgacgatc ttggtcgcgg cttccgccat cgtgtcggcg gtgatgatcg gcagacccga
     8581 gtcggcgagg atcttcttgc cgaggtcttc gttggtgcct ttcatgcgca ccacgagcgg
     8641 gacggagaga tgaacttcct tggccgcagc gaccacgccg gtggcgatgg tgtcgcagcg
     8701 catgatgccg ccgaagatgt tgaccaggat gcccttgacc ttggggttct tgagcatgat
     8761 cttgaaggct tcggtgacct tctcggtggt cgcgccgccg ccgacgtcga ggaagttggc
     8821 cggctcggcg ccgaacagct tgatcgtgtc catggtggcc atcgccaggc cggcaccgtt
     8881 caccaggcag ccgatgttgc cgtcgaggct gatgtaggcg aggtcgaact tggaggcctc
     8941 gatctcgtcg gcgtcctctt cgtcgaagtc gcggaaatcg acgatctccg ggtgacggta
     9001 gagggcgttg gagtcgaagt tgaacttggc gtccagagcc ttgatgttgc cgttgccttc
     9061 gaggatcagc gggttgatct ccgccagcga ggcatcggtc tccatgtagc aggtgtagag
     9121 cttcttgaag gcatcgaccg ccttggcgac cgagccttcc ggcacgccga tgcccttcgc
     9181 gagatcggtg gcctgcgcat cggtcaggcc gacgagcgga tcgacgaaga ccttgatgat
     9241 cttctcgggg gtgctgtggg cgacttcctc gatgtccatg ccgccttcgg aggaagccat
     9301 catggcgacc gtctgggtgg cacggtcggt cagcgcggcg acgtagtact cgtgcttgat
     9361 gtcggcgcct tcctcgatca gcaggttgcg caccttctgg ccctcggggc cggtctggtg
     9421 ggtcacgagc tgcatgccga ggatgtcgtt ggcgtgctgg cgcacttcgt cgagcgagcg
     9481 ggcgagcttg acgccgccgc ccttgccgcg gccgccggcg tggatctggg ccttgaccac
     9541 ccagatcttg ccgccgagtt cctcggccgc cttcacggca gcgtccaccg atacgcagtg
     9601 gaaaccgcgc ggcgtgacga cgccgtactt cctcaacagt tcttttgcct gatactcatg
     9661 aattttcatg gttgcccttc gatcgaagcc gcgacggcgg cagccggcgc gaacaggttg
     9721 atggcatgct tcggagcgct cgctccacga cgggcgccgt ctccctcgac cgtcgcccac
     9781 cgcatttgaa tcgggacccc ccgacccgac ccgcggaccg gacgcacacg ccgcggtcgc
     9841 aagaccccat aattataact ggttttgcgc ggtgcacagg catgggtccg aagcgcgccg
     9901 cggcgcttgc gaaggcatca cgggcgcccg cctcttgtcc cgagggcggc gggaaacgcc
     9961 gattagttca caccccgggc gaaacacgaa cggattgcgc aacgagtcgc tggaatggcg
    10021 gagacgactc tgctaaaact cggcaatcca aagatccacc gccggatgcg cggaacatga
    10081 acaacaacaa cctgccgctc gcaatcgccc tcgccgccgc attcctcggc gccagcccac
    10141 aagcggccgc agccgcgctt ggcgaggtgg ccgccctgtc ggcgatgggg gaaagctttc
    10201 gtgcggagat ccggcttccg ggcgcgaccc gctcggacgc ggaatgctat cgcgtcgttt
    10261 ccgttccggg tggcgaattc cccaccctgc agcaagcccg cttcgacgtc gccggcaccg
    10321 gcgccaacgc ccgcctggtg gtgcgagacg ccgctcgcgt cggcgaaccg gtgttgcggc
    10381 tgatcatcga gaacgtctgc gaatcgcgcc ttcgtcgcga atacaccctg ctgatgcctt
    10441 tcgggccgag cgcacagcgg cccgccacgg cggcggcccc cgccgccacg ccacgccccg
    10501 cggcgcgcgc accggcaacg cgtccggccc ctccggcacg acccgcatcc aagcctcgtg
    10561 cacgcaccct cagcaccacc ggcggcgagt cgctcctcac cctggccgag tccttgtatc
    10621 cggacgacga cagggcacga gcccgcttca tcgaggcgac cgccgcggcc aacccgaagc
    10681 tgttcgcgga catcgccgcg ctgacccgcg tcctgcccgc cggaaccacg ctgcgcatgc
    10741 ccgacctgcg cgcgcagcgt tccgcaactc gctcgccgcc gcccgaggtc acccccgccc
    10801 ccgcggccca gggcccggat cggctggtgg tcgacaaggc gctcgccacc cgcggccccg
    10861 gaacatccac gcccgcgacc acggccagcg acgggccgcg cagtcacgcc gagcgcgagc
    10921 gcgcgctcgc cgcagcgatc gaccgcagca tcatcgccga gatggaactg ctcgcccgga
    10981 tcaaggagct cgaggagatc caggcagccc tgaaggagcg cgtgctcgcc atgcaggcga
    11041 aggcgccccc gccggccgct gcggccatcg cggtcgccgc cgccccgccg cccccgccgc
    11101 cacccgtagc ggaagcagcg gctgaggcca ccccggcggc ggtcgatcgc gaggccggct
    11161 ggaaaagcga cggctacctg ttcgccgggc tcggcctcgc cgcgctggcc gtcgtggcgc
    11221 tgctgcgccg ttcgaggcgc ccggcgcgcc tcgcagcacc cagccggcct gcggacacgg
    11281 cgaccgccac cgcattgggc aacgccgagc cccgcaaggg gcgggcacgt gcagaagatg
    11341 ccggcttcgg cttcggcatc ggcaccgtgg acacccgcct cgagtggcct gcgggcaccg
    11401 agaccgaggt catccaggaa cacaagtccg cagtcgagct cgccgacatc atgatgagct
    11461 tcggtcgcgt ccgcggcgcg gccgagaccc tcgccgagtt catccgcggc aacccgcgcg
    11521 aggcggtcac gccctggctc aagctgctcg aggtctaccg tgccgccggg ctgcgcgacg
    11581 agttcaacgc gatcgccggg gagctcaaca agaccttcaa cgtcaccacg gtgaactggc
    11641 agagctacga cgcgctgcgc gcctcgaaga tgagcctgga agacctgccg catatctgcg
    11701 agagcctgca gaagacctgg cgcaccaccg cgtgccagcg ctacctgcag cagctgctgc
    11761 gcgacaaccg caacggcacc cgcgccggct tcccgttctc ggtgatcgac gagatcctca
    11821 ccctcaccgc gatcctcgag gaggacctcg gcccctgccc gccggcaggg agcgcgagca
    11881 cccagcgcta gacggggttg tcgaggtcga cgaagcgggc ctccagcccg agcacctcgt
    11941 tcaggtagtg cgcgatcgcg cgcgctccat aacgctcggt ggcatggtga ccggcggcga
    12001 tgtacggcac gcccgactcg cgcgccagat gcaccgtagg ctctgagatt tcgcccgaca
    12061 cgtagaggtc ggcaccggcc aggatcgcct gctcgaagaa gccttgcgcc gcgccggtac
    12121 accaggcgat ccggcgcacc cgacgctcgc cgtcgccgac cagcatcggc tcgcgcccga
    12181 gccgggccgc gagcgcgcgc gcgatctcct gcgctgactg gccctcctcc tccggacggc
    12241 cgatccagcc cagctcctgg tcggcgaagc gcgcctcgcc ctgccagccc atcaggcacg
    12301 cgagctgcgc gttgttgccg aactcggcgt gcacgtcgag cggcaggtgg taggcgaaca
    12361 ggctgatgtc gttggcgagc agggtgcgca ggcggcgacg ccggaagccg gtcacgcggc
    12421 cgtcgtcgcc cttccagaac aggccgtgat gaacgaagac ggcgtcatga ccaccggcga
    12481 ccgcgaggtc gagcagcgcc tggctcgcgg tcaccccgca cagcacgcgc agcacctcgg
    12541 ggcgtccttc cacttgcaga ccgtttgggc aataatcctt cagccgtgga gcgtcgagca
    12601 gggtgtcgag atgatccccg agttcggtga gctgcatgca tcctccttcg tcttcctcgt
    12661 cttccctgcg cgcgcggctt cacgaccggg cagcgccgcg acaggtcggg cgcgcgcccc
    12721 tcttctttca agtcccacat tatgcgccgc ttgtggctca tcttcgcgca ggccgtgacc
    12781 gtcagcgtcg ccgtgctgtt cgtgctcaac accctcaagc cggagtggct gcgccaggcc
    12841 acgccggcag cggtggtggc gatcctcgaa gcccccgcgg gcgccgagca agcgccggcg
    12901 gtgggttcct acgcccccgc ggcgcagcgt tcgatgccgg cggtggtgca catcttcacc
    12961 accaagggcg ggcgcggcca gcggcatccg ctgctcgacg acccgctgtt ccgccacttt
    13021 ttcggcgagc gcccggacag cgcgccgagc gagtccggcc tgggctcggg cgtcatcgtc
    13081 agccccgacg gctacgtgct caccaacaac cacgtcatcg agaccgccga cgcgatcgag
    13141 gtcgcgctca acgacggccg caagttcgcc gcccgcctgg tcggacgcga ccccgagacc
    13201 gaccttgcgg tgctgcgcat cgacggcgcc gacgtgctgc cggcgatcac cttcccggcc
    13261 gcggacagcc tcgcggtggg cgacgtggtg ctggcgatcg gcaacccctt cggcgtcggc
    13321 cagaccgtca ccatgggcat cgtctcggcg ctcgggcgca gccagctcgg catcaacacc
    13381 ttcgagaact acatccagac cgacgccgcg atcaacccgg gcaactcggg cggcgcgctg
    13441 gtcgacagcg ctggcagcct ggtcggcatc aacaccgcga tctactcgcg ctcgggcggc
    13501 tcgctcggca tcggcttcgc gatcccggtc tcgatcgcgc gcgacgtgct cgagcagatc
    13561 gtcgccaccg gcgaggtggt gcgcggctgg gtcggcgtgg agatccagga cctcacgccc
    13621 gagctcgcgg cctcgttcgg ctatcgcgac gccagcggcg cgctgatcgc cggggtgctg
    13681 cgcggcagcc cggccgatcg cgcgggcgta cgccccggcg acgtgctggt cgcgctcgac
    13741 ggcgagacgg tgcgcgaccc gcgcgcgatg ctcgacatgg tcgccgcgct gccaccgggc
    13801 aagcgtgcgg cattcagggt gcggcgcggc gccgaggaac tcgacctgga cgtcgaggtg
    13861 ggccgccgac cggttccgca gggcgcgcgc tgaaaggcgg cgaaggcacg gcccgaggcg
    13921 ctcagcggcg ctcgccctca ccctcggcga cgctgggcgc agccagctgc tgcaccgcct
    13981 cgtcagccgc ctcctgccgt ggcgaaggct tcgacagcat gcccgcgagc aggatgccga
    14041 gttcgtagag caggcacatc ggcacggcca gcatgaactg cgacaccacg tccggcggcg
    14101 tcacgatggc ggccaccacg aaggcgccga cgatcacgta gggacgcgac tcgcgcagct
    14161 tggcgacatc cacgatgccg gccttgacca tcaggatcac cgccaccggc acttcgaagg
    14221 tgatgccgaa ggcgatgaac atcgacatca cgaaggacag gtactgctcg atgtccggcg
    14281 cagggacgat gctcttgggc gcgaattcgg cgatgaactt gaacaccgtg ccgaacacga
    14341 agaagtagca gaacgccatg ccgaggagga agagcagcgt gctgccgagc accagcggca
    14401 gggccaggcg cttctcgtgc gcatacagcc cgggcgcgat gaaggcccag gcctggtaga
    14461 gcacccaggg cagcgcgagc acgaaggcca ccatcatcgt caccttgacc ggcacgaaga
    14521 agggcgtcac cacgccggtg gcgatcatgt tggtacccgc gggcagcgtg tccatcatcg
    14581 gcttggcgag gatgtcgtag atcgcgcccg cccagggcat caggcagacg aagacgatca
    14641 cgatcgcgag cagcgcgcgg atcaggcggt cgcgcagctc gaccagatgc gcgatgaagg
    14701 tttcctgttg ttcgctcatg ccttgacctt gtccgctccg gccgcggtgc ggggcacgct
    14761 atcgagcccg agctcgagct gcggggtcgg gactgcgacg ccggctgcag gcgtggcagg
    14821 cggattcccc acggacaccg gagcggctgc ggggctgttt gcaggagtgg ctgcagggct
    14881 gggcgctccg gcgccagcgg gagcaaccgc cgacgcggaa acaggcgact ccgggaggat
    14941 ggagcgcacc tcggcgaccg tgtcgccgat gccggactcc accccggcga ccccggtgcg
    15001 cacggacgcc tcgagttcct gcgcctgatg acgcacctgc tcctgcaact tcttcagctc
    15061 ctcgagctgc atctcgcgct ggatatcgga cttgacgtcg gagacgtagc gctgcacgcg
    15121 cccgagcagg tgcccggcgg tgcgcgcgac cttgggcagg cgctcgggcc cgaccacgat
    15181 cagcatcacg acaccgatca ccacgagttc cgaaaagccg aaatcgaaca tgtgtgctcg
    15241 ctcgagacag gggccgccgc cggcccgccg taaaacgaag gggcgctccg gtcagggcgc
    15301 ccccatgctg gttcgagacg cgaggttcag gaccggttct ggtcgacctt ctcgcgcgcc
    15361 tcgccttcga tcgtctggcc ctgcgagagc ttctgctggg aggcgtcgcc cgctccggcc
    15421 gagtcgccct ccttcatgcc ttccttgaag cccttcaccg cgccaccgag gtcggagccg
    15481 atgttgcgaa gcttcttggt gccgaaaacc aggaggatga tgaccagcac gatcagccag
    15541 tgccagatgc tgaaagaacc cataccgctc tccttaacgc ttcaacatgg gcggcagggg
    15601 atcgggcccg cccagaatgt gcaggtgcag atgatacacc tcctgcaggc cgacccttcc
    15661 ggtattgacg atcgtgcgga agccgtcggt gcagccctgc tcgcgggcga tcctgcccgc
    15721 cgcgaccatc agacgcccca tcgccgcctc gtgttccccg gacaactgcg ccatcgagtc
    15781 gacgtgaacc ttgggcacga ccagcacatg caccggcgcg accggatgga tgtcgtggaa
    15841 ggcgtagaca tgctcgtcct cgtaaacctt cttcgacggg atctcgccac gcacgatgcg
    15901 acagaagacg cagtcgctca tgcgcgcgcg ccttccgcgc tgcgggactt cttctcgtcg
    15961 atgcccgaca caccctcgcg gcggcgaaac tcggcgagca cgtcgtccac cgacaggccg
    16021 tggtgggcaa gcagcaccat ggagtggaac cagaggtcgg tgacctccca caccagatgc
    16081 agcatgtcct tgtccttggc cgccatgatg gtctcggcgg cttcctcggc gaccttcttg
    16141 cagatcgtgt cggtgccctt ctggtacagg ctggagacgt aggaagagtc cggatcggcc
    16201 ttcttgcgcg cggccagggt ctcggacacg cgatgcagca cttcgatatc gatcatttgt
    16261 agatctcctg cgggtctttc aaaaccggtt cgacggcctc ccagcgaccg tcggcgaaat
    16321 acttctggaa gaagcagctg tggcgcccgg tgtggcaggc gatgccgccg acctgctcga
    16381 tcctgagcag taccacgtcg ttgtcgcagt cgatgcgcat gtccagcacc ttctgcacgt
    16441 ggccggactc ctcgcccttg tgccacagct tgcgccgcga acgtgaccag tagatggctt
    16501 cgccggtctc ggcggtgcgc tgcagcgcct cgcggttcat ccaggcgaac atcagcacgt
    16561 cgccgctgga ggcctcctgt gcgatcaccg gcacgaggcc gtgctcgtcc cacttgatct
    16621 cgttcaacca gcgcgtgttc gtgctcacag ccgtacctcg atgccgcgcg cgcgcatcag
    16681 ctccttggcc tcgcgcacgg tgtgctgtcc aaaatggaag atgctggccg ccagcaccgc
    16741 gtcggcgcgg ccttcggaca caccctccgc aaggtgctcc aaggtgccga cgccgccgct
    16801 ggcgatcacc gggatacgca ccgcgtccga caccgcgcgt gtgagggcga gatcgaagcc
    16861 gctcttggtg ccatcgcggt ccatgctggt gagcaggatc tcgcccgcgc cgagcgactc
    16921 gaccttgcgc gcccactcga tggcgtccag gccggtgttg ttgcgcccgc cgtgagtgaa
    16981 cacctcccac ttgccgggcg cggtctgctt ggcgtcgatc gccaccacga tgcactggct
    17041 gccgaccttg ctggaggcgt catgcaccag ctgcgggttg ttgaccgccg cggtgttcat
    17101 gctgaccttg tcggcaccgg cgttgagcag gcggcgcacg tcctcgacca cgcgcacccc
    17161 gccaccgacg gtgagcggga tgaagacctg ctcggccacc tgctcgacca cgtgcaggat
    17221 gatgtcgcga tcgtcggagc tcgcggtgat gtcgaggaag gtgatctcgt cggcgccctg
    17281 ctcgtcgtag cggcgggcga tctcgaccgg atctccggcg tcgcgcagct cgacgaaatt
    17341 gacgcccttg accacgcgcc cggacttcac gtccaggcag gggatgatgc gtttggcgag
    17401 catcagcggc gctcagtaag gagggtcatt cggaggtacc gctcagctcg tcggcacgcg
    17461 cctgcgcggc ggcgaagtcc agcgtaccct cgtagatcgc gcgcccggtg atcgcgccca
    17521 tgatgccctc gtcctcgacc gcgcacagcc cgtcgatgtc acgcaggtcg gtgatgccac
    17581 cgctggcgat caccggaatg cgcagcgcgc gcgccaggcg cacggtggcc tcgatgttga
    17641 cgccggagag catgccgtcg cggccgatgt cggtgtagat caccgactcc acgccgtagt
    17701 cctcgaactt cttcgccaga tcgaccacgt cgtggccggt gagcttggac cagccgtcga
    17761 ccgcgacctt gccgtccttg gcgtcgaggc cgacgatgat gtgccccggg aaggcgctgc
    17821 aggcgtcgtg caggaagccc gggttcttga ccgcggcggt gccgatgatg acgtagctga
    17881 tgccgttgtc gaggtagtgc tcgatcgtgt cgaggtcgcg gatgccgccg ccgagctgga
    17941 ccgggatgtc gtcaccgacg acgtcggtga tcgcacggat cgcagcgccg ttcttgggct
    18001 tgccggcaaa ggcgccgttg aggtccacca ggtgcaggcg acgcgcgccg gcctcgagcc
    18061 agtggcgcgc catggcgccc ggatcggagg agaacaccgt ggcgtcgtcc atctcgccct
    18121 gtttgaggcg aacacattga ccgtccttga ggtcgatggc gggaatgagc agcataccgg
    18181 gatcagcagt ggaggaacgt gaagggaggc gccggcggct cagggctgcc agcggatgaa
    18241 attggccagc aggcgcaggc cggcggcggc gctcttctcg gggtggaact gagccgcgaa
    18301 gatattagcc cgcgctaccg cactggtaaa gcgaacgcca tagtcggtct cggccgcggt
    18361 gagcgcggca tccgcgggca cgacgaaata gctgtgcacg aagtagaagc gctcgccgtc
    18421 ggggatgcct tcccacatcg ggtgcgcgcc gcactggcgc acctcgttcc agcccatgtg
    18481 cggcaccttg agccggctgc cgtcggccgc gaccatcttc gcctcgggaa agcgcacgac
    18541 ctctccgggc aggatgccca gtccggggac gtcgccctcg gcgctgtgct ggaacagcat
    18601 ctgctggccg atgcagatgc cgaggaaggg tttttcggcc gccgcggcga gcaccgcggg
    18661 gcgcaggccg cgcgcgtcga gctcgcgcat gcagtcgggc atcgcgccct gccccgggaa
    18721 caccacgcgc tcggcggcag ccacgcgggc cgaatcggag gtgacgaaca cgtcgtggcc
    18781 gggcgccacg tgctcgatcg cctttgcgac cgagcgcagg ttgcccatgc cgtaatcgat
    18841 gatggccacg ctggtcatcg gcttgactcg cttttcgact ggaggacggc cgcgcagcgc
    18901 gaccgcgggg agggagggat cagagcgcgc ccttggtcga ggggatggtc cccgccgcgc
    18961 gctcgtcgtg ctcggcggcc atgcgcagcg cgcgggcgaa ggccttgaac accgtctcgc
    19021 actgatggtg ggcgttgtcg ccgcgcaggt tgtcgatgtg cagcgtgacg ccggcgtgat
    19081 tgacgaagcc ctggaagaac tcgcgcgcca ggtcgacgtc gaagttgccg atgcgggcgc
    19141 gggtgtaatt cacgaaatag tgcaggccgg ggcggccgga gaaatcgacc accacgcgcg
    19201 acagcgcctc gtcgagcggc acgtaggcgt ggccgtagcg gcgcaggccc ttcttgtcgc
    19261 cgagcgcctt ggcgaaggcc tggcccaggg tgatgccgac gtcctcgacg gtgtggtggt
    19321 cgtcgatgtg ggtgtcgccc tcgcagtgga tgtcgaggtc gatcagtccg tggcggacga
    19381 tctggtcgag catgtgatcg aagaagggca cgccggtctc gagccggccc tgcccgctgc
    19441 catcgaggtc gatgcgcacg gagatcttcg tttcgagggt gttgcgtgtg acttctgctt
    19501 gccgcatggg agctaccggc caaaatgggt tgtctccggg ccatgataac atcgcgcagc
    19561 gaactcgccg caatgcgccg cctatggcgc ggaaacggcg gcgctatcgc gttgcccttt
    19621 cgccacgcgc cgccgcaagg cgcggcgtac gcgtcgaacc cgccgttcca ccccaaccgc
    19681 agacacccgc atgagccgct tctggagcgc cgtcgtccac ggcctgaccc cctacgtgcc
    19741 gggcgaacag cccaagctcg acaatctcgt caagctcaac accaacgaac acccctgcgg
    19801 cccctcgccg aaggtactcg aggccatccg cgccgccacc ggcgacggcc tgcgcctcta
    19861 ccccgacccc aacgccgacg cgctcaaggc cgcgctcgcc cgccaccatg gcgtgcgccc
    19921 ggagcagatc ttcgtcggca acggctcgga cgaggtgctc gcacacgcct tcatggccct
    19981 gctcaagcac gagcgcgcgc tgtggttccc ggacatcacc tacagcttct acccggtgta
    20041 ttgcgggctg tacgacatcg agccgcgcat cgtgccgctg gccgaggact tctcgatccg
    20101 cgtcgaagac tacctgccgc gcggcgacga gcgcgccggc gcgatcatct tcccgaaccc
    20161 gaacgcgccc accggcaggc tgctcgcgct ccccgaggtc gagcgcatcg tctccgccaa
    20221 ccccgacgcg gtggtgctgg tcgacgaggc ctatgtggac ttcggcggcg acagcgcgat
    20281 cgcgctggtg gaccgccatc ccaacctgct ggtcacccgc accttctcca agagccgctc
    20341 gctcgccggc ctgcgcgtgg gctacgcggt gggcgacgcg gcgctggtcg aggcgctcga
    20401 gcggatcaag aacagcttca actcctaccc gctcgaccgc ctcgcgatcg ccggcgcggt
    20461 ggcctcggta gaggacgagg actacttccg cgccagctgc gcccaggtgg tcgcgacgcg
    20521 cgagaggctg gtcgccgagt tgcaggcgct cggcttcgag gtgctgccct cggcggcgaa
    20581 cttcatcttc gcccgccacc cggcgcgcga cggcgccgag ctcaccgccg cgctgcgcaa
    20641 gcgcgcgatc atcgtgcgcc acttcaaggc cgcgcgcatc gaccagttca tgcgcatcac
    20701 cgtgggcacc gacgcgcagt gcgccgtcct ggtgaccgcg ctgcgcgaga tcctcggcgg
    20761 ctgaagcggc tcagccgccg cgcgccgccg acggctgagc cgcggcgcgc ggcggcccca
    20821 gcagcagccg gttggcgagc agcaccgcga tcgacaccac caccacgatc acggtggcga
    20881 gcgcgttgat ctcgggcttg aggccgtggt gcaggcgcgc gaacaccagc accggcaagg
    20941 tcgtgctgcc cgggtcggac agcatcgcgg cgagcacgaa gtcgtccatg gacagcgtga
    21001 acgcgagcag ccagcccgcc gccagcgcgg gcgcgatcac cggcacggtg atcacgaaga
    21061 acaccttgag cgggggacag ccgaggtcga gcgccgcctc ctcgagcgcg cggtccatct
    21121 cgcgcaggcg cgacgccacc agcaccgcca cgtaggccgt gcacagcgtc gtgtgcgcca
    21181 cccagatcgc cgccaccccg cgtccgccca ggatggcgag cgccggatgg gtgaacagca
    21241 gcaccagcga caggccgacc accacctcgg gcatcaccat cggcgcgctc atcatgccga
    21301 ggaagaagcg gctgcccggg tagtcgccgg cgcgcaccag gatcaccgcg gccgcggtgc
    21361 cgaccaccac cgcggcggtg gcggcgagcg cgcccacgcg cagcgacagc agcaccgccg
    21421 cgtgcagctc gacatcccgc gcgagcgcgg cgtaccagcg cagcgagagg ccgtcgagcc
    21481 gggtggtgat ctcgccggcg gtaaaggaga acacgatcag gcacaggatg ggcacgtaca
    21541 ggaaggcgta cacgccgagc acccaggccc gcccgcccca gccgccgctc atgcgcccct
    21601 ccccgcgcgc cggccgtggc ggtgcagcag cacgatcggc gcgatcagca tcaccaccat
    21661 gaccaccgcc accgcggccg ccatcggcca gtcctggttg gggccgaagt catcccagat
    21721 gctgcgcccg atcgtcatca cgctgccgcc gccgagcagg tcggggatca cgaactcgcc
    21781 caccgccggg atgaacacca gcatcgagcc ggcgacgatg ccgcgcaggg acaagggcag
    21841 ggtgacgcgc aggaacaccg tcgccggccg tgcgccgagg tcgcgcgcgg cctcgagcag
    21901 acgcaggtcg agcttgacca ggttggcgta gagcggcagc accatgaagg gcaggtagct
    21961 atacaccatg ccgaccagca ccgcgccggt gttgtagagc agcggcagcg gctccgccac
    22021 cacgccgagg ccgagcagcg cctggttgat cagcccggtc tcgctgctgt cgagcagccc
    22081 catccaggcg tacacgcgca gcaggaagga ggtccagaac ggcagcatca ccagcatcag
    22141 cagggtgttg cgcatgacct cgggcgcgcg cgcgaggcgg taggcgaagg gatagccgag
    22201 gagcaggcag cacagcgtgg tgagcgccgc gagcaggacc gagttggcat aggcggcgag
    22261 atagggccgg tcggcgccgg gcgtggcgag cgccgcgagc tcatcgccga ggcgggcgta
    22321 gctggcggga tcgggacgga aggccggcgc cccgtccgcg gtcgtgccgg cgaagggcga
    22381 cacgtagggc ggcacggcga ggtcgggggt agacaggctg acgttgacga tcagcgcaaa
    22441 cggcagcacg aagaagaaca gcatccacgc ccatggcagc aggccgaccc agaagcggcc
    22501 atacccttgc gcggaggccg gatgcgccct catcgcagca gcagcacgcc gtcgggcgcc
    22561 ggccacgaca cccgcaccgg ctcgccgcgc gccggtggcg cggtctcgcc ccagtgcgcc
    22621 gcgggcacgc tggcgatcat cgcgcggcca ccgggcaggt gcagg
//
LOCUS       DAOTIN010000048        22143 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_2790_length_22143_cov_8.807724, whole genome shotgun sequence.
ACCESSION   DAOTIN010000048 DAOTIN010000000
VERSION     DAOTIN010000048.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 22143)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 22143)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22143
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2790_length_22143_cov_8.807724"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..718
                     /locus_tag="P5537_09065"
     CDS             <1..718
                     /locus_tag="P5537_09065"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009326 - formate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0008863 - formate dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_process: GO:0009061 - anaerobic respiration [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="formate dehydrogenase subunit gamma"
                     /protein_id="HRV78231.1"
                     /translation="LLILVPTAILLFWLVKGTMKLHGAKTGRKMLRFSGFERFVHWGT
                     AISFLLLAVTGLAILFGKHVLLPLIGHDGLGLLLNAGKLVHNYVGPLFAVFVLLMFFA
                     FLRDNVWRPIDAVWIRRAGGLLDGSHVPSGRFNFGEKTWFWFGVTILGFTVAASGLIM
                     DFPNLGEWTRSDMQTANIVHAIGAILMLALAFGHIYMGTLGAEGAYESMKTGYVDETW
                     AREHHEQWYLDIKAGKSGHP"
     gene            complement(879..3767)
                     /locus_tag="P5537_09070"
     CDS             complement(879..3767)
                     /locus_tag="P5537_09070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011237485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HRV78232.1"
                     /translation="MSRERLRAALAAQGGWILAVALAGSALFTGWAPLARVDLLAYDN
                     LEPLSRPALTPPDAVVVAVDEATLEALGRWPWNRAVHAELIDRLTASGVRAIGMPLLL
                     SEAAPGDDELAAALAASGRVVLAVAPRTADREGGGVGELLPNSTLAPRAAALGHVDVA
                     LDADGLARRTFARAGSEHAHWSALALATLEVAARTGTAGGDGIDARRGGGLRRVGASL
                     PWVREGELLLPVPDAQGHPRTLSYHSLLEQPARAYELAGRTVFIGVTAAGLDGGLATP
                     ASLAGKPMAAVEFHARAYEALRTGTVYRSTSALLPTGLALALAAAAAWLLGRNRHGGA
                     LTLGVLAAVPPALSVLALGSLKLWIPPTAAWLTLAVGGLLWLLRRLRSTRGSLVRARH
                     DADATLRSITDAVITIDERGRVTMINPVAERLTGLGRTAARGLTLAELIGDFSAQADA
                     ASAAVHDALGRRESVRLPEPLRWRAPDGSERALRMTTAPIGEVGKDGEGAVIVLSDVT
                     ETLAITARLQHEATHDLLTGLPNRALLLDRLQQALAGAIRRGSLVAMLFVDLDRFKRI
                     NDSLGHYVGDEVLRVVAERLQASVRAGDTVARWGGDEFIILMDNLADHSAVVRVARKL
                     IDLLEREVETTGGTGIVLSCSVGISIGPQDSADAQTLLSMADKAMYRAKLEGGSRYTF
                     YGPEMNTWSRDRLSLEAALRHGLANREFELFYQPQIDVASGRLAGLESLIRWHRPERG
                     LVRPDEFIPAAEESGIIRSIGEWAIHEAAEQAARWHQDGLLGAPLAVNVSARQCSDMA
                     IVDTIRTTLADTGLEPRMFKVELTESTAMRDPERAAELLRSIHALGAGIAVDDFGTGY
                     SSLSLLKRFPISELKIDKSFVSDIAKDSDDAAIVRSTIALAHGLGIEVVAEGVETESQ
                     LAFLARHGCDSAQGFLFAKPLPAGEIRAWLDTPPPHVERAVRNSRGEG"
     gene            complement(3847..5481)
                     /locus_tag="P5537_09075"
     CDS             complement(3847..5481)
                     /locus_tag="P5537_09075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004375399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FecR domain-containing protein"
                     /protein_id="HRV78233.1"
                     /translation="MSSPVRPQLRSLRRTFAGLLLAACASPALAEDFVYVVQPGDNPW
                     NLTRRYLKSIDYWPRIQDYNRILEPETIQPGSVLRIPVAWMRGERGGAQVIDVRGDVE
                     AHRAGRSEALVPGMQVLPGMQVRSGANSSLTLEFPDGSRSLVGADTTFGMRKLERLRA
                     SGAQQLELQLERGYIENLVNPVRSGGRYIIQTPAAVAAVRGTDFRITAVLDGVRAETL
                     EGEVALQNARGQTRLPAGRGSYAERGKFPERSSELLPAPDLGGLPTVIDRVPFRIPIA
                     PVGGALRYRTQIAPAGGFTVLASDRSADEAAALGGGELPDGRYRVRVRAVDARGLEGH
                     DGEREILIDARPEPPFPSVPPADGFATEDKIRFAWAHDPQATAYHFQLAADAGFERIL
                     VQRDDLREAGLALDEALPAGDYHWRVGLSTAEEGRGPYSNVQRFRRPPPGPQAEPPDV
                     DGDTLQLRWRASAGAVAYQVEFARDADFSTPAHHLETREPELVMERPEGGLWHVRIRS
                     QEPGSPPGPWSKPQQVEVPHDHWRALLVLLPLLLVP"
     gene            5672..6835
                     /locus_tag="P5537_09080"
     CDS             5672..6835
                     /locus_tag="P5537_09080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004375401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="THUMP domain-containing protein"
                     /protein_id="HRV78234.1"
                     /translation="MAETFFSPCPRGLEALLAEELASFGARAARVVHGGVNWEGDWDA
                     CRRANLESRLATRVLWRVGQGRYRAEVDIYKLAYSVTWAKWFTADDTIRIYVTAQKSP
                     LKSLEFITLRVKDAVCDHFRTVAGRRPSVDTANPAVRIHLFLTADTATLYVDTSGEPL
                     YKRGYKPAAVEAPLKENLAAGILRLTGWQADEALVDPMCGSGTFLIEAAQMALDIAPG
                     LGRGFAFERLRIHDRTAWAAQRRAAEQRRKPARVLPVFGSDVVGEWVRRSRMNLDAAG
                     LADCVRLDRADVLERTPPAAAGVMVANPPYGVRIGEAEELLAFYPRLGDALKQRWGGW
                     RCYLFSADPELPKRIGLKATRRTPLFNGALECRLFEYRMVAGSNRERAPRPQE"
     gene            complement(6858..7994)
                     /locus_tag="P5537_09085"
     CDS             complement(6858..7994)
                     /locus_tag="P5537_09085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043107 - type IV pilus-dependent motility
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilT/PilU family type 4a pilus ATPase"
                     /protein_id="HRV78235.1"
                     /translation="MERDQALKFMHDLLRLMLQKNGSDLFITAGFPPAIKVDGRIVPQ
                     SNQILQPQHTTELARAIMNDRQAADFETHKECNFGISPAGIGRFRANAFVQQGRVALV
                     LRTIPQKIPNFQELGLPPVLTEIALAKRGLVIFVGGTGTGKTTSLASLVDYRNENTYG
                     HIITIEDPIEFVHQHKNCIVSQREIGIDTESWMTALKNTLRQAPDVILMGEIRDRETM
                     DYAIAFAETGHLCLATLHANSANQAIDRIINFFPEDRRQQLLMDLSLNLRAMVSQRLL
                     PMKDRKGRVPAVEVLLNSPLIADLVFKGNVPEIKDVMKRSRELGMQTFDQSLFQLYED
                     ELISYEDALRNADSVNDLRLQIKLNSRHGDPGAPGGGIKNLGIL"
     gene            complement(8035..9078)
                     /locus_tag="P5537_09090"
     CDS             complement(8035..9078)
                     /locus_tag="P5537_09090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004375404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043107 - type IV pilus-dependent motility
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HRV78236.1"
                     /translation="MDITELLAFAVKNKASDLHLSAGLPPMIRVHGDVRRINLPPLEH
                     KEVHAMVYDIMNDAQRKQFEESWECDFSFAVPNLARFRVNAFQQNRGAGAVFRTIPSK
                     VLTLEELNCPKIFKEIAHQPRGIVLVTGPTGSGKSTTLAAMLDYVNENEYGHILTVED
                     PIEFVHESKRCLVNQREVHRDTQSFNNALRAALREDPDVILVGEMRDLETIRLALTAA
                     ETGHLVFGTLHTSSAAKTIDRIVDVFPAAEKDMVRSMLSESLRAVISQTLLKTKDGQG
                     RVAAHEIMIGTPAIRNLIRENKIAQMYSSIQTGQNIGMQTLDQCLVDLVRRNVVSAAE
                     ARVKAQNKDSFAA"
     gene            9204..9911
                     /locus_tag="P5537_09095"
     CDS             9204..9911
                     /locus_tag="P5537_09095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HRV78237.1"
                     /translation="MTTIAARLDAVRARIAAAARHAGREPADVTLLAVSKTWPAEAVR
                     EAAAAGQRAFGENYVQEGVDKVEALRALDLEWHFIGPLQSNKTRPVANAFDWVHGIDR
                     LRIAERLSAQRDVHLPPLNVCIQVNVSGEDSKSGVAPAEAGALAHAVAALPRLRLRGL
                     MCIPEPSADEAVLRARFAVLRGLRDELRSAGLVLDTLSMGMSHDLEPAIAEGASIVRV
                     GTAIFGERPRPASTPSA"
     gene            9953..10777
                     /gene="proC"
                     /locus_tag="P5537_09100"
     CDS             9953..10777
                     /gene="proC"
                     /locus_tag="P5537_09100"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HRV78238.1"
                     /translation="MKITFLGGGNMATALIGGLLERGFAAADLQVVELGDAARDALVQ
                     RFGVRAVGAFDDAALACDVLVLAVKPQQMKAALAPLAGRLSGQLVISIAAGLRMADLG
                     RWLGAAGRPYARLVRVMPNTPALIGAGVTGLYADPSVDAAGREAAGRILGAVGSTVWA
                     GAEAQMDAVTAISGSGPAYVFHFIEALESAGRSLGFDEAGARRLAIDTVLGAAKLAAD
                     SEDAPAVLRQKVTSKGGTTEAALASLAAAGWHDALVAAVAAAEARGRELGEQLGKD"
     gene            10781..>11058
                     /locus_tag="P5537_09105"
     CDS             10781..>11058
                     /locus_tag="P5537_09105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HRV78239.1"
                     /translation="MLANILLLVIDVAASFLTLMLLARFFMQWQRISFRNQLGQFVVS
                     TTDWIVRPLRRFIPGLFGLDMASLLPAWVVQVLLVMFELSLRGAAFSG"
     assembly_gap    11059..11158
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(11318..12595)
                     /locus_tag="P5537_09110"
     CDS             complement(11318..12595)
                     /locus_tag="P5537_09110"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HRV78240.1"
                     /translation="MNILISNGRVVDPANRVDAVHDVYVSGGKIVALGAAPDGFKAER
                     TIDASGLVVAPGFIDLAARLREPGYEYRATLESEMEAAMAGGVTSLAIPPDTDPALDE
                     PGLVEMLTYRAKKLNRAHIYPVGALTLGLKGERLSEMAELVEAGCVAFSQANVPVVDN
                     TVLMRALQYAATFGFRVWLQPLAPFLSRVGHAHDGEVSTRLGLSGIPVAAETVALYTY
                     LELARLTGARLHITRLSSAAGLALIDQARAEGMDVSCDVSINHVHLCDMDIGYFNPNC
                     HLVPPLRSQRDREALARGLADGRIDALCSDHTPVDDDAKQTPFSESEPGATGLELLLP
                     LTLKWADAAGLPLLDGLARITSDAAKIVGITKAGHLSPGARADVCVFDPAAHVKITRE
                     GLRSQGKNTPFLGMELPGKVRYTLVEGQVMFEG"
     gene            complement(12629..13588)
                     /locus_tag="P5537_09115"
     CDS             complement(12629..13588)
                     /locus_tag="P5537_09115"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HRV78241.1"
                     /translation="MRNPQLNQHGELQHLLTLDGLPRDILTAILDTAAPFTEVAEREV
                     KKLPLLRGKSVFNLFFENSTRTRTTFEIAAKRLSADVVNLNINTSSAAKGESLLDTVD
                     NLCAMQADMFVVRHAASGAPMLIAQHLQNTGRDHIHVVNAGDGRHAHPTQGLLDMYTI
                     RHFKRDFTNLTVAIVGDVLHSRVARSQIAALTTLGVPEVRVIGPKTLLPTEVERLGVR
                     VFHDMSEGLRGVDVVMMLRLQNERMNGALLPTPQEYYKIWGLTAEKLALARPDAIVMH
                     PGPMNRGVEIDSAVADGAQAVILPQVTFGIAVRMAVMSMLGSR"
     gene            complement(13641..14144)
                     /gene="pyrR"
                     /locus_tag="P5537_09120"
     CDS             complement(13641..14144)
                     /gene="pyrR"
                     /locus_tag="P5537_09120"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HRV78242.1"
                     /translation="MKDLDAEALCRQLAEQIRPHVGPATALVGIYTGGLWLAERLHAE
                     LGIAQPLGAIDVSFYRDDYASKGLHASPKKTEIPFDVDAAHVILIDDVLYTGRTTRAA
                     LNELFDFGRPARVELAVLVDRGGRELPVAARYCAHTLSAPLAREQNLELQRDDHGQFS
                     LKLTQRA"
     gene            complement(14131..14637)
                     /gene="ruvX"
                     /locus_tag="P5537_09125"
     CDS             complement(14131..14637)
                     /gene="ruvX"
                     /locus_tag="P5537_09125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002930398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HRV78243.1"
                     /translation="MPEAAAAARSPADNSATRSAPDTLPARGSVLGFDFGLARIGVAS
                     GELETGLASALTTLHAEANDERFAAIARLIGEWQPVALVVGIPTHLDGREHELTARCR
                     RFANQLHGRHALPVFTVDERLSSVAAEAELAEAGRKGWRERKAVLDAAAARILLQTFL
                     DTRRHERP"
     gene            complement(14630..15196)
                     /locus_tag="P5537_09130"
     CDS             complement(14630..15196)
                     /locus_tag="P5537_09130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgE/AlgH family protein"
                     /protein_id="HRV78244.1"
                     /translation="METPTANFTHHFLIAMPNMVDPHFTRTLTYIAEHNEQGALGIIV
                     NRPIDMTLASLFERIEVPLEAEGFAAQPVYFGGPVQTDRGFVLHRPLGEWHSTLKVTD
                     EIGLTSSRDVLQAIGAGGEPRDVIVTLGYAGWAAGQLEQELLDNAWLTVPADLGIVFE
                     LPPEERLVAAMQKLGIDFTNLSDVAGHA"
     gene            15299..16753
                     /locus_tag="P5537_09135"
     CDS             15299..16753
                     /locus_tag="P5537_09135"
                     /EC_number="4.1.99.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003904 - deoxyribodipyrimidine
                     photo-lyase activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HRV78245.1"
                     /translation="MSSALVWFRRDLRSFDHAALYHALRFADRVHCVFVFDTAILDAL
                     PSRHDRRVDFIHASLAELDAALDAMARAAGGAGGGLIVRHGRAEDEIPRLAVALGVDK
                     VFANRDYEPDAIVRDSRVAQALAEAGIGYEDFKDQVIFERDEVLTQTGKPYSVFTPYK
                     NAWLKKLDDFNVRSYAVEKCAAHLAPKPAGETLPGLAEIGFAPTNLAELNMPVGMSGG
                     KRLFDDFAARIERYKRARDFPAVKGVSYLSTHLRFGTVSIRQLAAHARARGGEGAETW
                     LSELIWRDFYHQILWHHPQVVERAFRPEYDAVKWDDAPELFVAWCEARTGYPIVDAAM
                     RQLNQTGYMHNRLRMIVASFLTKDLGVDWRLGERYFAVHLNDYDLAANNGGWQWAAST
                     GCDAQPWFRIFNPVTQSEKFDPEGRFIRRYLPELARVPDKFIHAPWTMGGIDQTACRT
                     KIGVDYPGPVVDHAAARERTLQRFGVVKNDAQGG"
     gene            17011..18171
                     /locus_tag="P5537_09140"
     CDS             17011..18171
                     /locus_tag="P5537_09140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HRV78246.1"
                     /translation="MTDAAFDFDRLIDRRSLPSEKWGRYAGRDVLPLWVADMDFAAPP
                     AVLAALHRRIDHGVFGYTDAWPSLIDAVIEGVRRDHGWTIEADWLVWLPGVVTGFNLA
                     CSLAGQPGDGVLTATPVYPPFLTAPANTGRVLQRVELVLRDGRWQCDWEALEAACTPS
                     TRLLLLCSPHNPVGRVFDADELRRLADFAARHDLLVCSDEIHCGLVLDADRPHRPLAA
                     LDEATARRTITLMAPSKTWNIPALYCAFAIIPDPALRRRYRHAMRGVVPHVNVLGMVA
                     AEAAYRDGDAWRQALLAYLRGNRERVLEAVAAVPGLATTRPEATYLAWIDCRAMMAAR
                     GIANPAAFFEAAGVGLSDGEAFGAPGFVRLNFGCPRATLDEALARMGRALAE"
     gene            complement(18222..21785)
                     /locus_tag="P5537_09145"
                     /pseudo
     CDS             complement(18222..21785)
                     /locus_tag="P5537_09145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004335711.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Hpt domain-containing protein"
BASE COUNT         2932 a         7523 c         8122 g         3466 t
ORIGIN      
        1 gctgctcatc ctcgtgccca cggccatcct gctgttctgg ctggtcaagg gcacgatgaa
       61 gctgcacggg gccaagaccg ggcgcaagat gctgcgcttc tcgggcttcg agcgcttcgt
      121 gcactggggc acggcgatca gcttcctgct gctcgccgtc accgggctgg cgatcctgtt
      181 cggcaagcac gtgctgctgc cgctcatcgg ccatgatggc ctgggcctgc tgctcaacgc
      241 cggcaagctg gtgcacaact acgtcggccc gctgttcgcg gtcttcgtgc tgctgatgtt
      301 cttcgccttc ctgcgcgaca acgtgtggcg gccgatcgac gcggtgtgga tccgccgtgc
      361 cggcggcctg ctcgacggca gccacgtgcc ctccgggcgc ttcaacttcg gcgagaagac
      421 ctggttctgg ttcggcgtca ccatcctcgg cttcaccgtg gcggcgtccg ggctgatcat
      481 ggatttcccg aacctgggcg agtggacgcg ctccgacatg cagaccgcga acatcgtgca
      541 cgcgatcggc gccatcctga tgctggcgct ggccttcggc cacatctaca tgggcacgct
      601 cggcgccgaa ggcgcctacg agtcgatgaa gaccggctac gtcgacgaga cctgggcgcg
      661 cgagcaccac gagcagtggt atctcgacat caaggcgggc aagtccgggc atccctgagc
      721 cgggcgccga gtcccccttt ccctctacct ctccctcgcc cgggccgccc tcccttcggc
      781 ccgggacgat tcggccccga gcggcgaacc cgccgcccgg ggtcgcgttt ttttggagca
      841 cgctttcccg tccgagcgca gcgcagcggc tccgcgcctc acccctcacc ccttgagttg
      901 cgcaccgcac gctccacgtg gggcggcggt gtgtcgagcc aggcgcggat ctcgccggcg
      961 ggcagcggct tggcgaacag gaagccctgc gcggagtcgc agccgtggcg cgcgaggaag
     1021 gcgagctggg actcggtctc cacgccctcg gccaccacct cgatgcccag gccgtgcgcg
     1081 agtgcgatgg tgctgcgcac gatcgccgcg tcgtcgctgt ccttggcgat gtcgctgacg
     1141 aagctcttgt cgatcttcag ctcggagatc gggaagcgtt tgagcagcga gagggaggaa
     1201 tatccggtgc cgaagtcgtc caccgcgatg cccgcgccga gcgcgtggat gctgcgcagc
     1261 agctcggcgg cgcgctccgg gtcgcgcatc gctgtggact cggtgagctc gaccttgaac
     1321 atgcgaggct ccagcccggt gtcggcgagg gtcgtgcgga tggtgtcgac gatcgccatg
     1381 tccgagcact ggcgcgcgga cacgttcacg gccaggggcg caccgagcag gccgtcctga
     1441 tgccagcgcg cggcctgctc ggccgcctcg tggatcgccc attcgccgat gctgcggatg
     1501 atcccgctct cttccgcggc cgggatgaac tcgtccggcc gtacgaggcc gcgctcgggc
     1561 cggtgccagc ggatcagcga ttccagtcct gcgaggcggc cgctggcgac gtcgatctgc
     1621 ggctggtaga agagctcgaa ctcgcggttc gcgaggccgt ggcgcagcgc cgcctccagg
     1681 ctcaggcggt cgcgcgacca ggtgttcatc tccggtccgt agaaggtgta gcggctaccg
     1741 ccctcgagct tggcgcggta catcgccttg tccgccatcg acagcagggt ctgggcgtca
     1801 gcgctgtcct gcgggccgat gctgatgccg acgctgcacg acagcacgat gccggtgccg
     1861 ccggtggtct cgacctcgcg ctcgagcagg tcgatgagct tgcgcgccac cctcaccacc
     1921 gcgctgtgat cggcaaggtt gtccatcagg atgatgaatt cgtcgccgcc ccagcgcgct
     1981 accgtgtcgc ccgcccgcac cgaggcctgc aagcgctccg cgaccacgcg cagcacctcg
     2041 tcgccgacgt agtggcccag gctgtcattg atgcgcttga agcggtcgag gtcgacgaag
     2101 agcattgcga ccaggctgcc gcggcggatc gctccggcga gcgcctgctg caatcggtca
     2161 agcagcaagg cgcggttggg caggccggtg agcaggtcgt gggtggcttc gtgctgcagg
     2221 cgggcggtga tcgcgagcgt ctcggtgacg tcgctgagca caatgacagc gccttcaccg
     2281 tctttgccaa cttcgccgat cggcgcggtg gtcatgcgca gggcgcgctc gctgccgtcg
     2341 ggcgcgcgcc agcgcagcgg ctcgggaaga cgcacgctct cgcggcgtcc gagggcgtcg
     2401 tggaccgcgg cgctcgcggc gtccgcttgt gcactgaaat ctccgatcag ctcggcgagt
     2461 gtgagcccgc gcgcggcggt gcggcctagt ccggtcaggc gctcggcgac cgggttgatc
     2521 atggtgacgc gaccgcgctc atcgatggtg atcaccgcgt cggtgatcga gcgcagcgtc
     2581 gcgtcggcgt cgtggcgggc gcggaccagc gaaccgcgcg tactgcgcag ccggcgcagc
     2641 agccatagca ggccgccgac ggcgagcgtg agccaggccg cggtgggcgg gatccaaagc
     2701 ttcaggctgc cgagcgcgag gacgctcagc gcgggcggta ccgccgcgag gacgccgagc
     2761 gtgagcgcgc cgccgtgccg attgcgtccg agcagccagg ctgctgcggc ggcgagcgcg
     2821 agcgccagcc cggtgggaag cagtgcggaa gtgctgcggt acacggtgcc ggtgcgcagc
     2881 gcctcgtacg cgcgcgcgtg gaactccacc gcggccatcg gcttgccggc gagcgaggcg
     2941 ggggtcgcca ggccgccgtc caagccggcc gcggtgacgc cgatgaagac cgtgcggccg
     3001 gcgagttcgt atgcgcgtgc gggctgctcg agcaggctgt ggtaggagag cgtgcgcggg
     3061 tgtccctgcg catccggcac cggcagcagc agctcgccct cgcgcaccca gggcaggctg
     3121 gcgccgacac ggcgcaggcc gccgccacgg cgggcgtcga tgccgtcacc tcccgcggtt
     3181 ccggtgcgag ctgcgacctc gagggtggcg agcgcaagcg cgctccagtg cgcgtgctcg
     3241 ctgccggcgc gggcgaaggt gcgtcgtgcg agtccgtcgg cgtcgagcgc gacatccacg
     3301 tgcccgagcg ccgcggctcg gggtgcgagg gtggagttgg gcagcagctc gccgactccg
     3361 ccgccttcgc ggtccgccgt gcgcggcgcc accgcaagca cgacgcggcc ggaggcggcg
     3421 agcgcggcgg cgagctcgtc gtcgccgggt gcggcttcgg acaacaacag cggcatgccg
     3481 atcgcgcgca cgcccgaggc cgtcagtcga tcgatcagct cggcatgcac cgcgcggttc
     3541 cacggccagc gcccgagcgc ctccagcgtg gcctcgtcca ccgcgaccac gactgcgtcc
     3601 ggtggggtga gcgcgggtcg ggaaagcggt tcgaggttgt cgtaggcgag caggtcgacg
     3661 cgagcgagcg gggcccagcc ggtgaacagc gcggagcctg ccagcgcgac tgcgaggatc
     3721 cagccgccct gggcggcgag cgctgcgcgc aggcgctccc ggctcatggg gcgactcccc
     3781 tggcgtcatg cacccgcgtc acaagggggc ggcagtacgc catcgcgcga gcagtcgccg
     3841 gttgcctcat ggtacgagca gcaggggcag caggacgagc agtgcgcgcc agtggtcgtg
     3901 cggtacctcc acctgctgcg gcttgctcca tggtcccggc gggctacccg gctcctggct
     3961 gcggatacgt acgtgccaaa ggccgccctc ggggcgctcc atcaccagtt cgggctctcg
     4021 cgtctcgagg tggtgcgcag gggtggagaa atcggcgtcg cgggcgaact caacctggta
     4081 ggccacggcg cctgcgcttg cgcgccagcg cagctgcagg gtgtcgccgt caacgtcggg
     4141 gggctcggcc tgcgggccgg gcggggggcg gcggaagcgc tgcacgttcg agtaggggcc
     4201 gcggccctct tccgcggtgc tcagcccgac gcgccaatgg tagtcaccgg cgggcagcgc
     4261 ctcgtcaagg gcgagcccgg cctcgcgaag atcgtcgcgc tggacgagga tgcgttcgaa
     4321 gcctgcgtct gcggcgagct ggaagtggta ggcggtggcc tggggatcgt gtgcccaggc
     4381 gaagcggatc ttgtcctcgg tggcgaagcc gtctgcgggc ggcacgctcg ggaagggggg
     4441 ctcggggcgg gcgtcgatga ggatctcgcg ctcgccgtca tgtccctcca gcccgcgggc
     4501 gtccaccgcg cgcacgcgca cgcggtagcg cccatcgggg agctcgccgc cgccaagcgc
     4561 cgcggcctcg tcggcgctgc ggtcggaggc gagaacggtg aagccgcccg cgggggcgat
     4621 ctgggtgcgg tagcgtagcg cgccgcccac cggcgcgatc gggatgcgga aggggacgcg
     4681 gtcgatcacc gtgggcaagc cgcccagatc gggcgccggc agcagctcgg aggagcgctc
     4741 cggaaacttg ccgcgctcgg cgtagctgcc gcggcctgcg ggcaggcggg tctggccgcg
     4801 tgcgttttgc agtgcgacct cgccctccag tgtctcggcg cgcacgccgt caaggactgc
     4861 ggtgatgcgg aagtcggtgc cgcgcaccgc cgccaccgcg gccggggttt ggatgatgta
     4921 gcgtccgccg ctgcgcaccg gattgaccag gttctcgatg tagccgcgct cgagctggag
     4981 ctcgagctgc tgtgcccccg aggcgcgcag gcgctcgagc ttgcgcatgc cgaaggtggt
     5041 gtcggcgccg accaggctgc ggctgccgtc gggaaactcc agcgtcaggc tgctgttcgc
     5101 gccgctgcgc acctgcatgc cgggaagcac ctgcataccg ggtacgagcg cctcgctgcg
     5161 gccggcccgg tgtgcctcga cgtcgccgcg cacgtcgatc acctgtgcgc cgccgcgctc
     5221 gccgcgcatc cacgccaccg ggatgcgcag cacgctgccg ggctggatgg tttccggttc
     5281 gaggatgcgg ttgtagtcct ggatgcgcgg ccagtagtcg atgctcttga ggtagcgccg
     5341 ggtcaggttc cacggattgt cgccgggctg cacgacatag acgaagtcct ccgcgagcgc
     5401 ggggctcgca caggctgcca gcaagaggcc ggcgaaggtg cggcgcagac tgcgcagctg
     5461 cgggcggaca ggggaggaca tcggcatttc tgggccatgg gtgggcgacc acgaattctt
     5521 ctccaggaat gcgcgggatg cgcggaaata attccttgct gaccagggga aaagggcagc
     5581 gggtgcccgc gccggggtgt ccgtggcgag gttctcgggg ggcgcccggc gggcggtaca
     5641 atgccggctt ttccagcgcg cggagcgacc catggccgaa accttctttt ccccctgtcc
     5701 tcgcggcctc gaggcgctgc tggccgaaga gctggcgagc ttcggcgcgc gcgcggcgcg
     5761 cgtggtgcat ggcggggtga actgggaggg cgactgggat gcctgccggc gcgccaacct
     5821 cgagagccgg ctcgccaccc gcgtgctgtg gcgggtgggg caggggcgct accgtgccga
     5881 agtcgacatc tacaagctcg cctacagcgt gacctgggcg aagtggttca ccgccgacga
     5941 caccatccgc atctacgtca ccgcgcagaa gtcgccgctg aagagcctgg agttcatcac
     6001 cctgcgggtg aaggacgcgg tgtgcgacca cttccgcacc gtggccgggc ggcggccgag
     6061 cgtggatacc gccaacccgg cggtgcgcat ccacctgttc ctcaccgccg acaccgccac
     6121 gttgtacgtc gacaccagcg gcgagccgct ctacaagcgc ggctacaagc cggcggcggt
     6181 ggaggcgccg ctgaaggaga acctcgccgc cggcatcctg cgcctgaccg gctggcaggc
     6241 ggacgaggcc ctggtcgatc cgatgtgcgg cagcggaacc ttcctgatcg aggccgcgca
     6301 gatggcgctc gacatcgcgc ccggtctggg ccgcggcttc gccttcgagc gcctgcgcat
     6361 ccacgaccgc actgcctggg ccgcgcagcg gcgcgccgcc gagcagcgcc gcaagccggc
     6421 gcgcgtgctg cccgtcttcg gttcggacgt ggtgggcgag tgggtgcggc gcagccgcat
     6481 gaacctcgac gccgccgggc tggccgattg tgtgcgcctg gatcgcgccg acgtgctcga
     6541 gcgcacgccg ccggccgctg cgggggtgat ggtggcgaat ccgccctacg gggtgcgcat
     6601 cggcgaggcg gaggaactcc tcgccttcta tccccgcctg ggcgacgcgc tcaagcagcg
     6661 ctggggcggc tggcgctgct acctgttcag cgccgatccc gagctgccca agcgcatcgg
     6721 cctcaaggcg acgcggcgca cgccgctctt caacggggcg ctcgagtgcc gcctgttcga
     6781 gtaccgcatg gtggccggca gcaaccgcga gcgcgcgccg cgtccgcagg agtgaggacg
     6841 cgcgcggcgg cctgtcccta aaggatgccg aggttcttga tgccgccgcc gggtgcgccc
     6901 gggtcgccgt ggcggctgtt gagcttgatc tgcaggcgca ggtcgttgac cgagtcggcg
     6961 ttgcgcagcg cgtcctcgta gctgatgagc tcgtcctcgt agagctggaa cagcgactgg
     7021 tcgaaggtct gcatgccgag ctcgcgcgag cgcttcatga cgtccttgat ctcggggacg
     7081 ttgcccttga agaccaggtc ggcgatcagc ggcgagttga gcagcacctc gacggccggc
     7141 acccggccct tgcgatcctt catcggcagc aggcgctgcg agaccatcgc ccgcaggttc
     7201 agcgacaggt ccatcagcag ctgctggcgg cggtcttccg ggaagaagtt gatgatgcgg
     7261 tcgatcgcct ggttggcgct gttggcgtgc agcgtggcga ggcagaggtg gccggtctcg
     7321 gcgaaggcga tcgcgtagtc catggtctcg cggtcgcgga tctcgcccat caggatcacg
     7381 tcgggcgcct gccgcagggt gttcttcagc gcggtcatcc aggactcggt gtcgatgccg
     7441 atctcgcgct gcgagacgat gcagttcttg tgctggtgta cgaactcgat cgggtcctcg
     7501 atggtgatga tgtggccgta ggtgttctcg ttgcggtagt cgaccagcga ggcgagcgag
     7561 gtcgtcttgc cggtgccggt gccgccgacg aagatcacca ggccgcgctt ggcgagggcg
     7621 atctcggtga gcaccggcgg caggccgagt tcctggaagt tggggatctt ctgcgggatg
     7681 gtgcgcagca ccagcgcgac gcggccctgc tgtacgaagg cgttggcgcg gaagcggccg
     7741 atgccggccg gcgagatgcc gaagttgcac tccttgtggg tctcgaagtc ggcggcctgg
     7801 cggtcgttca tgatcgcgcg cgccagctcc gtggtgtgct gcggctgcag gatctggttc
     7861 gattgcggca cgatgcgacc gtcgaccttg atcgcgggcg gaaagccggc ggtgatgaag
     7921 aggtccgagc cgttcttctg cagcatcagc cgcagcaggt cgtgcatgaa cttgagggcc
     7981 tggtcgcgtt ccatggtgtg cgtgctcctt cccgggcggg cgggtgagtg ccgctcaggc
     8041 ggcgaagctg tccttgttct gcgccttcac gcgcgcttcc gcggccgaca ccacgttgcg
     8101 ccgcaccagg tcgacgaggc actggtcgag ggtctgcatg ccgatattct gaccggtctg
     8161 gatcgaggaa tacatctgcg cgatcttgtt ctcgcggatc aggttgcgga tcgccggcgt
     8221 gccgatcatg atctcgtgcg ccgcgacccg gccctgcccg tccttggtct tgagcagggt
     8281 ctgcgagatc accgcgcgca gggattcgga aagcatcgag cgcaccatgt ccttctcggc
     8341 cgcggggaag acgtcgacga tacggtcgat ggtcttggcc gccgacgagg tgtgcagggt
     8401 gccgaacacc agatggccgg tctcggcagc ggtcagcgcc aggcggatgg tctcgaggtc
     8461 gcgcatctcg cccaccagga tcacgtcggg gtcctcgcgc agcgcggcgc gcagcgcgtt
     8521 gttgaaggac tgggtgtcgc ggtgcacctc gcgctggttc accaggcagc gcttggactc
     8581 atgcacgaac tcgatcgggt cctccacggt gaggatgtgt ccgtactcgt tttcgttcac
     8641 gtagtcgagc atcgccgcca gcgtggtgga cttgcccgag ccggtcggcc cggtcaccag
     8701 cacgatgccg cgcggctggt gggcgatctc cttgaagatc ttcgggcagt tgagctcctc
     8761 cagggtcagc accttgctcg ggatggtgcg gaacaccgcg cccgcgccgc ggttctgctg
     8821 gaaggcgttg acgcggaagc gcgcgaggtt gggcacggcg aaggagaagt cgcactccca
     8881 ggactcctcg aactgcttgc gctgcgcatc gttcatgatg tcgtacacca tggcgtgcac
     8941 ttccttgtgc tcgagcggcg gcaggttgat gcggcgcacg tcgccatgca cgcggatcat
     9001 cggcggcaga ccggcggaga ggtggaggtc ggaagccttg ttcttgaccg cgaaggcgag
     9061 cagttcggtg atgtccatgg tattccggcg cgatgggcgg cccggtcgcc tgcggggtgg
     9121 ggcgcaggcc gggcctcagg gtgggcaatg gagcgatgct atactttcgc cgccccgaaa
     9181 tcccaggaaa taggccacgg aacatgacga cgatcgctgc gcgcctcgac gcggtgcgcg
     9241 cccgcatcgc cgccgcggcg cgacatgccg ggcgcgagcc cgccgacgtg acgctgctcg
     9301 cggtgagcaa gacctggccc gcggaggcgg tgcgcgaggc cgccgccgcc gggcagcgcg
     9361 ccttcggcga gaactacgtg caggaaggcg tggacaaggt cgaggcgctg cgcgcgctcg
     9421 acctcgaatg gcatttcatc ggcccgctgc agagcaacaa gacgcgtccg gtggcgaatg
     9481 ccttcgactg ggtgcatggc atcgaccgcc tccggatcgc cgagcgcctg tcggcccagc
     9541 gcgacgtcca tctgccgccg ctcaacgtct gcatccaggt caacgtcagc ggcgaggaca
     9601 gcaagagcgg cgtggcgccg gccgaggccg gcgcgctcgc gcacgcggtc gcagccctgc
     9661 cgcggctgcg cctgcgcggc ctcatgtgca tccccgagcc gagcgcggac gaggccgtgc
     9721 tgcgcgcgcg cttcgccgtg ctgcgcgggt tgcgcgacga gctgcgcagc gccgggctcg
     9781 tgctcgacac cttgtcgatg ggcatgtcgc acgacctcga gccggcgatc gccgagggcg
     9841 cgagcatcgt gcgcgtgggc acggcgatct tcggcgagcg cccccgcccc gcttccaccc
     9901 cttcggcctg acgcgcgcac gcgcgccccg gccccaacct gcaggttcat ccatgaagat
     9961 cacctttctc ggcggcggca acatggccac cgccctcatc ggcggcttgc tcgaacgcgg
    10021 cttcgccgcc gccgacctcc aggtcgtcga gctcggcgac gcggcgcgcg acgcgctcgt
    10081 gcagcgcttc ggcgtgcgtg cggtcggggc cttcgacgac gcggcgctcg cctgcgacgt
    10141 cctcgtgctg gcggtcaagc cgcagcagat gaaggccgcg ctggcgccgc tcgcaggccg
    10201 cctctccggc cagctcgtca tcagcatcgc cgccggactg cgcatggcag acctcgggcg
    10261 ctggctgggt gccgccgggc gcccgtatgc ccgtctggtg cgcgtgatgc ccaacacccc
    10321 ggcgctgatc ggcgcgggcg tcaccggcct gtacgccgat ccgtcggtgg acgccgccgg
    10381 ccgcgaggcc gccgggcgca tcctgggcgc ggtcggcagc accgtgtggg cgggcgccga
    10441 ggcgcagatg gatgcggtca ccgcgatctc gggcagcggc cctgcctacg tgttccactt
    10501 catcgaggcg ctcgagtccg ccgggcgcag cctcggcttc gacgaggccg gggcgcgccg
    10561 gctggcgatc gataccgtgc tcggcgcggc gaagctggcg gcggactcgg aagacgcgcc
    10621 cgccgtcctg cgtcagaagg tcacctcgaa ggggggcacc accgaggccg ccctcgccag
    10681 cctggcggcg gccggctggc acgacgccct ggtcgctgcg gtcgctgccg ccgaggcacg
    10741 cggccgcgag ctcggcgaac aactcggcaa ggactgaccc atgctcgcca acatcctgct
    10801 gctggtgatc gacgtcgccg ccagcttcct gacgctgatg ctgctcgcgc gcttcttcat
    10861 gcagtggcag cgcatctcct tccgcaacca gctcggccag ttcgtggtca gcaccaccga
    10921 ctggatcgtg cgcccgctgc gccgcttcat ccccgggctg ttcggcctcg acatggcgag
    10981 cctgctgccg gcctgggtgg tgcaggtgct gctggtgatg ttcgagctca gcctgcgcgg
    11041 cgcggccttc agcggcaann nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnct
    11161 gctggtgctg cagatcgtgc tcatgctgct cgccgaggcg cgcaacggct tcgcgccact
    11221 gctgttcgga ggctgagcgc cgcgcgcaca tgcggggagc cgcggcccgg ccgggccgcg
    11281 agcttcacat cgaatcgcgc gctgaccggg gctgccctca gccctcgaac atcacctggc
    11341 cctcgaccag cgtgtagcgc accttgccgg gcagctccat gccgaggaag ggcgtgttct
    11401 tgccctggct gcgcaggccc tcgcgcgtga tcttgacgtg cgcggccggg tcgaacacgc
    11461 acacgtcggc acgcgcgccc ggcgacaggt gcccggcctt ggtgatgccg acgatcttcg
    11521 ccgcgtcgga ggtgatgcgc gcgagcccgt cgagcagcgg cagtcccgcg gcgtccgccc
    11581 acttcagcgt cagcggcagc agcagctcga ggccggtggc gccgggctcg gactccgaga
    11641 acggcgtctg cttggcgtcg tcgtccaccg gggtgtggtc ggagcacagt gcgtcgatgc
    11701 gcccgtcggc gaggcccctg gcgagcgcct cgcggtcgcg ctggctgcgc agcggcggga
    11761 cgaggtggca gttggggttg aagtagccga tgtccatgtc gcacaggtgc acatggttga
    11821 tcgacacgtc gcagctcacg tccatgcctt cggcgcgcgc ctggtcgatg agcgcgaggc
    11881 cggccgcgga ggacaggcgg gtgatgtgca ggcgggcgcc ggtgaggcgc gcgagctcga
    11941 gataggtgta cagcgccacg gtctcggcgg cgaccgggat gccggacagg ccgaggcggg
    12001 tcgacacctc gccgtcgtgg gcgtggccca cgcgtgacag gaagggcgcc agcggctgca
    12061 gccagacgcg gaagccgaag gtggcggcgt actgcagcgc gcgcatcagc acggtgttgt
    12121 ccaccaccgg cacgttggcc tgcgagaagg cgacgcagcc ggcctcgacc agctcggcca
    12181 tctccgacag gcgttcgccc ttgagaccga gggtgagggc accgaccggg tagatgtggg
    12241 cgcggttcag cttcttggcg cggtaggtca gcatctcgac caggccgggc tcgtcgagcg
    12301 cggggtcggt gtcgggcggg atcgccaggc tggtgacgcc gccggccatc gccgcctcca
    12361 tctcggattc gagcgtggcg cggtattcgt agccgggctc gcgcaggcgc gcggcgaggt
    12421 cgatgaagcc gggagcgacg accagcccgc tggcgtcgat ggtgcgctcg gccttgaaac
    12481 cgtcgggcgc agcgccgagg gcgacgatct tgccgccgga gacatagacg tcatgcaccg
    12541 cgtcgacgcg gttggccgga tcgacgacgc ggccgttgga gatcaggatg ttcatgcgtg
    12601 gttccttgtt cctgtgctgt ccgcggcttc agcggctgcc gagcatgctc atcaccgcca
    12661 tgcgcacggc gatgccgaag gtgacctggg gcaggatgac cgcctgcgcg ccgtcggcca
    12721 ccgcggagtc gatctcgacg ccgcggttca tcgggccggg gtgcatcacg atcgcgtcgg
    12781 gcctggccag cgccagcttc tcggcggtga ggccccagat cttgtagtac tcctgcggcg
    12841 tgggcagcag cgcgccgttc atgcgctcgt tctgcaggcg cagcatcatc accacgtcca
    12901 cgcccctgag gccctcgctc atgtcgtgga agacgcgcac gccgaggcgc tcgacctcgg
    12961 tcggcagcag ggtcttgggc ccgatcacgc gcacttcggg cacgccgagc gtggtcagcg
    13021 cggcgatctg gctgcgcgcc acgcgcgagt gcagcacgtc gccgacgatc gccaccgtga
    13081 gattggtgaa gtcgcgcttg aagtggcgga tggtgtacat gtcgagcagg ccctgcgtcg
    13141 ggtgcgcatg gcggccgtcg ccggcgttga ccacgtggat gtggtcgcgc ccggtgttct
    13201 gcaggtgctg ggcgatcagc atcggtgcgc cgctggcggc gtggcgcacg acgaacatgt
    13261 cggcctgcat cgcgcacagg ttgtcgacgg tgtcgagcag gctctcgccc ttggcggccg
    13321 agctggtgtt gatgttgagg ttcaccacgt cggccgacag gcgcttggcg gcgatctcga
    13381 aggtggtgcg ggtgcgcgtg gagttctcga agaagaggtt gaacacgctc ttgccgcgca
    13441 gcagcggcag cttcttcact tcgcgctcgg ccacctcggt gaacggggcg gcggtgtcga
    13501 ggatggcggt gaggatgtcg cgcggcagac cgtcgagcgt gagcaggtgc tgcagttcgc
    13561 cgtgctggtt gagctggggg tttcgcatcg ggcgtgcctc ggagtcagcg gtgggcaagg
    13621 ggaaaggggg aggtgcggga tcaggcgcgc tgggtcagct tcaggctgaa ctgcccgtgg
    13681 tcgtcgcgct gcagctccag gttctgctcg cgcgcgagcg gcgcggacag ggtgtgggcg
    13741 cagtagcgcg cggccaccgg cagctcgcgc ccgccgcggt cgaccagcac ggcgagctcg
    13801 acccgggccg ggcggccgaa gtcgaacagc tcgttgagcg cggcgcgggt ggtgcggccg
    13861 gtgtagagca cgtcgtcgat caggatcacg tgggcggcgt cgacgtcgaa ggggatctcg
    13921 gtcttcttcg ggctggcgtg caggcccttg ctggcgtagt cgtcgcggta gaaggagacg
    13981 tcgatcgcgc ccagcggctg ggcgatgccg agctcggcgt gcaggcgctc ggccagccac
    14041 aggccgccgg tgtagatgcc gacgagcgcg gtggcggggc cgacgtgggg gcggatctgt
    14101 tcggcgagct gccggcacag ggcttcggcg tcaaggtctt tcatggcgtc gtgtgtccag
    14161 gaaggtttgc aggaggatgc gggcggcggc ggcgtcgagc accgccttgc gctcgcgcca
    14221 gcccttgcgg ccggcctcgg cgagctcggc ctcggcggcg accgaggaca ggcgctcgtc
    14281 gacggtgaac accggcaggg cgtggcggcc gtggagctgg ttggcgaagc ggcggcagcg
    14341 cgcggtgagc tcgtgctcgc ggccgtcgag gtgggtgggg atgccgacca ccagcgcgac
    14401 cggttgccat tcgccgatca gcctggcgat ggcggcgaag cgttcatcgt tcgcctcggc
    14461 gtgaagcgtg gtgagcgcgc tggccaggcc ggtctcgagc tcgccgctgg cgacgccgat
    14521 gcgcgccagg ccgaagtcga agccgagcac gctgccgcgc gcggggaggg tgtccggggc
    14581 ggaccgggtg gcgctgttgt ccgcagggga ccgtgcggca gcggccgcct caggcatgtc
    14641 cggcgacatc gctcaggttg gtgaagtcga tgccgagctt ctgcatggcg gcgacgaggc
    14701 gctcctcggg cggaagctcg aacacgatcc cgaggtcggc ggggacggtg agccaggcgt
    14761 tgtcgaggag ctcctgctcg agctggccgg cggcccagcc ggcgtagccg agggtgacga
    14821 tgacgtccct gggttcgccc ccggcaccga tcgcctgcag cacgtcgcgg ctgctggtga
    14881 ggccgatctc gtcggtgacc ttgagcgtgg agtgccattc gccgagcggg cggtgcagca
    14941 cgaagccgcg gtcggtctgc accggaccgc cgaaatacac cggttgcgcg gcgaagccct
    15001 cggcctcgag cgggacctcg atgcgctcga agaggcttgc gagggtcatg tcgatcggcc
    15061 ggttcacgat gatgccgagc gcgccctgtt cgttgtgctc ggcgatgtag gtgagcgtgc
    15121 gcgtgaagtg cggatcgacc atgttcggca tggcgatcag gaagtggtgc gtgaagttgg
    15181 ccgtgggcgt ttccatgcgc ggcattctac gccgatcgcc gggcttcttg gcgtgggggc
    15241 gcgcgcgtgc gtggtccgga tgcgtcataa ttccgtgtct ttgtcctgga caaaaaacat
    15301 gtcttccgcc ctcgtctggt tccgccgcga cctgcgcagc ttcgatcacg ctgcgctcta
    15361 ccatgccctg cgcttcgccg accgcgtgca ttgcgtcttc gtcttcgata ccgcgatcct
    15421 cgacgcgctg ccctcgcgcc atgatcgccg cgtcgacttc atccatgcca gcctcgccga
    15481 gctcgatgcg gcgctcgacg ccatggcgcg cgccgcgggc ggcgcgggtg gcgggctgat
    15541 cgtgcggcat ggccgcgccg aggacgagat cccgcgcctg gccgtcgcgc tcggcgtcga
    15601 caaggtcttc gccaaccgcg actacgagcc cgacgccatc gtgcgcgaca gccgggtggc
    15661 gcaggcgctg gccgaggccg gcatcggcta cgaggacttc aaggaccagg tgatcttcga
    15721 gcgcgacgag gtgctcaccc agacgggcaa gccctacagc gtgttcacgc cctacaagaa
    15781 cgcctggctg aagaagctcg acgacttcaa cgtccgctcg tacgcggtgg agaagtgcgc
    15841 cgcgcacctg gcgccgaagc ccgccggcga gaccctgccg ggcctcgccg aaatcggctt
    15901 cgcgcccacc aaccttgccg agctgaacat gccggtcggc atgagcggcg gcaagcgcct
    15961 gttcgacgac ttcgccgcgc gcatcgagcg ctacaagcgc gcgcgcgact ttccggcggt
    16021 gaagggggtc agctatctgt cgacgcacct gcgcttcggc acggtgtcga tccgccagct
    16081 cgccgcccac gcccgcgcgc gcggcggcga gggcgccgag acctggctgt cggagctgat
    16141 ctggcgcgac ttctaccacc agatcctgtg gcaccacccg caggtggtcg agcgcgcctt
    16201 ccgccccgaa tacgacgcgg tgaagtggga cgacgcgccc gagctcttcg tcgcctggtg
    16261 cgaggcgcgc accggctacc cgatcgtgga cgcggcgatg cgccagctca accagaccgg
    16321 gtacatgcac aaccgcctgc gcatgatcgt cgcatccttc ctcaccaagg acctcggtgt
    16381 ggactggcgc ctgggcgagc gctattttgc cgtccacctc aacgactacg acctcgccgc
    16441 caacaacggc ggctggcagt gggcggcctc gaccggttgc gacgcccagc cctggttccg
    16501 catcttcaac ccggtcaccc agtccgagaa gttcgacccc gagggccgct tcatccgccg
    16561 ctacctgccc gaactcgcgc gcgtgcccga caagttcatc cacgccccgt ggaccatggg
    16621 cggcatcgac cagaccgcgt gccggacgaa gatcggcgtc gactacccgg gaccggtcgt
    16681 ggaccacgcc gccgcgcgcg aacgcacgct gcaacgcttc ggcgtggtga agaacgacgc
    16741 ccagggcggg tagaacaaac cgttcggcca tttctcacgc aaggccgcgg gaccggggtg
    16801 gcgggcgccg tctgcattcg cggcccttcg cttcgctgcg ggctgccctc ggtggaggac
    16861 accgcggggg cggcgacgca aactcggcgc tcctgaagtt ggcacccgcc accccggtgc
    16921 cgcggccgaa gcggagccgt gccgccctgc gccgcccttc gccaattgcg ggacaatgac
    16981 gccccacaac cccttaccgg acgcccctcc atgaccgacg ccgccttcga cttcgaccgc
    17041 ctcatcgacc gccgcagcct gccgagcgag aagtggggcc gctacgccgg ccgcgacgtg
    17101 ctgccgctgt gggtcgccga catggacttc gccgcgccgc ccgccgtcct cgccgccctg
    17161 caccggcgca tcgaccacgg cgtcttcggc tacaccgacg cctggccttc gctgatcgac
    17221 gccgtgatcg aaggcgtgcg gcgcgaccac ggctggacca tcgaggccga ctggctggtc
    17281 tggctgcccg gcgtcgtcac cggcttcaac ctcgcctgca gcctcgctgg ccagcccggc
    17341 gacggcgtgc tcaccgcgac gccggtgtac ccgcccttcc tcactgctcc cgccaacacc
    17401 ggccgcgtgc tgcagcgcgt cgagctggtc ctgcgcgacg ggcgctggca gtgtgactgg
    17461 gaagcgctcg aggccgcgtg cacgccctcg acccgcctgc tgctgctgtg cagcccgcac
    17521 aacccggtcg gtcgggtgtt cgacgcggac gaactgcggc gcctcgccga cttcgccgcg
    17581 cgccacgacc tgctggtgtg ctccgacgag atccactgcg gcctggtgct cgacgcggac
    17641 cgcccgcatc gcccgctcgc agcgctcgac gaggccaccg cacggcgcac catcaccctg
    17701 atggcgccgt ccaagacctg gaacatcccg gcgctctact gcgccttcgc gatcatcccc
    17761 gaccccgcgc tgcgccggcg ctaccgccac gccatgcgcg gtgtcgtccc gcatgtgaac
    17821 gtgctcggca tggtggccgc cgaggccgcc taccgcgacg gcgacgcctg gcggcaggcg
    17881 ctgctcgcct acctgcgcgg caaccgcgag cgcgtgctgg aggcggtcgc ggcggtgccc
    17941 gggctcgcga cgacgcgccc cgaggccacc tatctcgcct ggatcgactg ccgcgcgatg
    18001 atggccgcgc gcggcatcgc caacccggcg gccttcttcg aggccgccgg ggtcgggcta
    18061 tcggatggcg aggccttcgg cgcccccggc ttcgtccggc tcaatttcgg ctgcccgcgc
    18121 gcgacgctcg acgaggcact cgcgcgcatg gggcgtgcgc tggccgaata gccgccgcgc
    18181 cgcctctcgc tccttgcgcc tgacgcctta cggtcgacgc atcaggcctc acccgccctc
    18241 gcgtagcgcg ccaccagggc gagcagctct tcctcctgat agggcttgcc gagatagtgg
    18301 tcggcaccga cctccaatgc atagcggcgg tgcttttccg ccaggcgaga ggtgatcacc
    18361 accaccggca ggtcgtgcag gcgggcgtcg gcgcggatgt tgcggacgag gtcgaagccg
    18421 tccatgcgcg gcatctcgat gtcggtgagc accacgtcgg gcttcaggtc gatgagctgc
    18481 tcgagcgcgt ccacgccgtc cttggcggtg atcacgcgat agccctcgcg ctcgagcagg
    18541 cggccggtga tcttgcgcac ggtcagcgag tcgtccacca ccatcaccgt cggcaggtgc
    18601 agcggaggcg gtgcctcggt ggcggggccg aacaacccct cgtgcgtctc gtccgtcccg
    18661 gaggtacgtg aagcgagcgc gaccgggttg aggatcagca cgatctcgcc gtcgccgagc
    18721 acggtcgcgc cgctcatgcc gatgatgcgg gtgagctgcg ggccggcgtt cttgacgatg
    18781 acctcctggt tgccgcgcag cccgtccaca tgcagcgcca gcgtctgcgc gcccgcgcgc
    18841 agcagcagca cccagctgta gcgcgcctcg gcggggcgcg cctcgccatc gccgagcagg
    18901 cgcggcaggt agcggtaggg atagtgttcg ccctgccatt cggtgccgtg cgcctgctgc
    18961 atggcctgca gcgcgtcggg cttgagttcc atcgcctgca cgatcatgtt cgcgggtacg
    19021 gcccagctgc ggccgagcgc ctccaccagc agggtctgcg tcaccgcgag ggtgagcggc
    19081 agccggatcg agaagcgggt gcctgcgccc gcacgactgg cgacctcgac gcggccaccg
    19141 gcggcggcgg tctgggcctt caccacgtcc atgccgacgc cgcggccgga gacggcggac
    19201 acctcgcgcg cggtgctgaa gccggagacg aagatcaggt tgaccaggcg gcgctcgtcg
    19261 acacgctcgt cggcgccaag caggccgcgt gcgcgtgcct gcgccgcgat gcgctcgagg
    19321 tccaggccgg cgccgtcgtc ggcgatctcg atggcgatct cgttgccttc ctggcgcacc
    19381 gtcaactcga tgttgccggt ctcgggcttg ccggccgcga ggcgctcgcc cggcagctcg
    19441 atgccgtgcg cgatcgcgtt gcgcagcagg tgttcgagcg gtgcggccat ctgctccagt
    19501 acgctgcggt cgacctcgat gcgtccgccg cgcaggtcga gcgcggcgcg cttgccgagt
    19561 tcgcgtgcgc tctgccgcac cacccggtag agccggctgg cgaggctgtc gaagggcagc
    19621 atgcgcacct gcatcaggcc ttgctgcagc tcgcgcgcca tgcgcgcctg gctgccgagc
    19681 gcgagttcgg cgccgtccag gttgtgcagc aggccctgct gcacggtggt cacgtcgttc
    19741 acgctctccg ccatcatccg cgtgagctcc tgcaggcggg tgtagcggtc gagctcgagc
    19801 ggatcgaagt cggtgtcccg ggtgccggcc tgggcgatgc gcgactgcat ctgcacctcg
    19861 gcctggatct cgacctcgcg cagctggttg cgcaggcgga tcacgttctc ggtgaggtcg
    19921 agcagcgaac gccgcaggct gcgcagctcg ccctcgaccc ggctgcgcgc gacgccgatc
    19981 tcgccggcct ggttgacgaa gcggtcgacg cgctcggcgc gcacccgcaa ggtgggggtg
    20041 gcgaggggct cggcctcggg cgcggcctcc ctgccacctt cttccgcgct ggcgggcgcg
    20101 gggggcgcct gcagcgccgc ttcgccgagg gcgagctcgt cgatgacctg ctcgcagcgg
    20161 tcgatgccgt gcgcgagcgc ctcggcgagc actgcggccg gctcacgcgc ggcgagaccg
    20221 tcctccagat gcgattcgag ctcgtgcagg tgggcgccga ggcgcattgc ccccgccatg
    20281 cgcgcgctgc ccttgagcga gtgcagcagg cgtgcgaccg cgcgcggtgc ctcctcgtcg
    20341 tcggcctgcg tgcgccagcg gcgcagggtg gcgtggagct cggcggtggt ctcggcggcc
    20401 tcttcgagga agatcggcag cagctgggtg tcgatgtcgt cctgcgcatg ctccgccgcg
    20461 cccggctccg cgctgcggac cgccatgggc acgactgcgg gcgcgaccgc cgtatcgtcc
    20521 cgggagatcg tggcggctgc ggtgtcggcg tccgcagcgg tgaccgtttc cgcggagcgc
    20581 cctggcggcg cggtgaaaac ctcttcgtcg atggcctcga agcgtgcgac gagttcgtcc
    20641 gccgacgtag gtgtgcgtcc tgcggcgatc tcctcgcgca tcgcgcgcag ggcgtcgagg
    20701 gtgtcgccga acagcgccag atcgtccacc cccggtaccc ggccggtatc ggcgagccgc
    20761 tccagcctgt gctccagagc gcggccgagg cgatgcgcgg cctcggcgcg cacggtgccc
    20821 gagatgccgg cgagggtgtg ggcggcgcgt atccccgcgg tcgagggcgg atggtctgcg
    20881 ccgtgcagcg cgcgcaactc ctgttcgagc gcggcgaggt gctgggccga ttcgctgcag
    20941 tagagctcgt gcagcgcgcg cgagatctcg ccatcgccga tgcgctgcgt gtcgccggga
    21001 aggctgtcgc cgggttcgcg ggcgccgagc tcgtccgccc cgtcgtgcga tgcttcgagc
    21061 gccgggatgc cttctgcatg cgcttcgatc ggcgcttcgc cgagcgctgt cggcaagggc
    21121 tcgaaggctt cgagcaggat cggggcgccc tcgtcgagcg gctcgatgaa ctcgatcagg
    21181 tcttcctcgg cttgcgccgc gaaggccgga acgtcggccg ccgccgcagg cggcgggttt
    21241 tcgccgatgt cgccgtcgag caggaagtcc acgctgtcga tgtgcatcgc atcgggggcg
    21301 gactccgtgg gcgcgggctc cgccgcgatt gccgccatcg gcttggggag cgtggggagc
    21361 tgtccggagg agccggcgag gccggcatcg tgcaccggct cggccgcttc gtgcaggcgc
    21421 ctcgcctcgg cgatgagggc tgcggtgtcg ccgccgcccg cctctccatg ttcgagctgc
    21481 gccacccagg tggagaacac gcggtggcct tcggcaacga gggccagcag ggcgggcgtg
    21541 agcggccagt cgagctgcag ccagcgattg agcgcctgct ccaccgccca tgcggtgtcg
    21601 ccgagctggg cgagcccgac catgcggcca ctgcccttga gggtgtggaa accacgccgg
    21661 atggtgacca gctgcgcgag ctcgtccgct tcgccgcgca ggtcatctag cccggctgcg
    21721 atcccagcga gcacctcgtg ggcctcctcg atgaagatcg ccagcagttc ggcgtcgatc
    21781 tcggcctcga tggggactgg cgtcgggggc gtggagggag gggatgcgtc cgttcgtgca
    21841 gcctgcgggg ccggcgcacg cgcctgtgcg ctggcgtcgg cgtggccgag gtcgctctcc
    21901 gggaggggca gcgtcatgct ggcccccgtt cgagccgcct cggtgggggc ttcgagttcg
    21961 tcgaggacgc tgaaatcgag gtccgggaaa tcgacgccga acgggttccc ggtcatgtcc
    22021 cgggacgccg attccgtcgg cggtgctgcg atgcccgggc ttgccgaagc ggtgcccgcg
    22081 agcgccgcaa ccggcacggt ctcggctgcc ggtgtgtcgc cgaggtcggg ttctgcagtc
    22141 gcc
//
LOCUS       DAOTIN010000049        21881 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_2845_length_21881_cov_8.209154, whole genome shotgun sequence.
ACCESSION   DAOTIN010000049 DAOTIN010000000
VERSION     DAOTIN010000049.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 21881)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 21881)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21881
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2845_length_21881_cov_8.209154"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..722
                     /locus_tag="P5537_09150"
     CDS             <1..722
                     /locus_tag="P5537_09150"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78247.1"
                     /translation="DGTEQTTGTVTIVVEASVQTERIGDAPARVTSSAQFATAWSDPL
                     LHGIRHTADADSLAPTWSAVTFGTINNGVLSGGDIYTGDLGVSGQTVASSTVRQEIDG
                     TEALRFDLAAQASSVTVDLSRLFANDDGSMLYEAGRLRLLNGNGDVVAETVFVADSTL
                     GHKTVSLDSATAFSTVELSAGLYDGTDFVFGGYADADGEFASPASADALGNAHGSEFL
                     VDWIEVDFQVPLVGVGDPLSI"
     gene            778..1521
                     /locus_tag="P5537_09155"
     CDS             778..1521
                     /locus_tag="P5537_09155"
                     /inference="COORDINATES: protein motif:HMM:NF019225.2"
                     /note="PEP-CTERM proteins occur, often in large numbers,
                     in the proteomes of bacteria that also encode an
                     exosortase, a predicted intramembrane cysteine proteinase.
                     The presence of a PEP-CTERM domain at a protein's
                     C-terminus predicts cleavage within the sorting domain,
                     followed by covalent anchoring to some some component of
                     the (usually Gram-negative) cell surface. Many PEP-CTERM
                     proteins exhibit an unusual sequence composition that
                     includes large numbers of potential glycosylation sites.
                     Expression of one such protein has been shown restore the
                     ability of a bacterium to form floc, a type of biofilm;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-CTERM sorting domain-containing protein"
                     /protein_id="HRV78248.1"
                     /translation="MNFNDWHGFRYCNTPAFRIEGTRMNAVNCGGPLIRSLFVAGLIA
                     TAPMASAAEVLVSQPFKNGGPSYLSDLGGAVNADSFNLSGSANVSAIAWWGTHVDDQQ
                     LGGFSVRLAETLDALLDNSSALGGSVSRGDDAVGEDDEPSPDGPRKLHRFQLDLTAPL
                     GSLGGNYYLAIGNETVEWFWATGTEGDLKSFYLDTGNPNLPAAWAEDDTTDMSFEVIG
                     ERQTVPEPGILALLGLAGIGGLLARRRRR"
     assembly_gap    1646..1745
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(2358..4187)
                     /locus_tag="P5537_09160"
     CDS             complement(2358..4187)
                     /locus_tag="P5537_09160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004360821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HRV78249.1"
                     /translation="MNPSGRPPGLPPSPGPSPVEPFVADLSEGAEAGVYLALLELLDE
                     GLLITGDEVVLDANSAACRLLGRDYRDVAGRPLANLFPDGQAFLAARARLLIEGERRG
                     RLDFALPDGGVRTLEFNCAPRLRPGIHAIILSPPAATEEDATRDPDLTAASPTAGARH
                     VFDDAPSMSMYLTSHDPLTGLANRRMLEARFGDCAVRAAGRHGSIAIARLDLDGFGAV
                     NRSLGESAGDEVLRRIARRLAAAAGPEALVARERSDSFIVLLPDPEHPGNADQFAEGL
                     LRAVAEPFELGGGPQRITASAGLALYPQDGRNLDTLLRNARSALEQARRLGGNRCSAF
                     HTRLDGPGFDSSQLERGLRHALQADELTLHFQPLVDARSGRTRAGEALLRWRHPEFGV
                     LPYRQFMNAVGDPRLLADVGDWVLATACHHAADWPPAHDGTRLRLTVNVAVEQLMRGD
                     FAVRVATALRASGLKADRLELDLDEKVLALDSPTLAATLERIAATGVRLSIDDFGRGL
                     SSIPRLRRYPLAALKLDPELVRGVGRSEDSEAIVEAVGAFAGTLGLEIYARGVENRGQ
                     QAFLCALDCHLQQGPLFGRPLAAREFAAAIAAAGGGDRVRRHP"
     gene            complement(4310..5818)
                     /locus_tag="P5537_09165"
     CDS             complement(4310..5818)
                     /locus_tag="P5537_09165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HRV78250.1"
                     /translation="MSFADLGLIPELLQAVADAGYTEPTPIQRQAIPTVIAGHDVMGG
                     AQTGTGKTAGFTLPLLHRIARHANTSTSPARHQTRALILAPTRELAMQVFESVKTYSK
                     HLPLRSVCVYGGVDIRPQQAELRRGIEIVIATPGRLLDHIEQKSINLSQVEVLVLDEA
                     DRMLDMGFIPDIKRILALLPKQRQSLLFSATFSDEIKRLADQMLKDPQLIEVARRNMV
                     SETITHVVHPVSSGMKRNLLAHLLRHKPDTQALVFVDTKLMCGRLAHYLERSGISADA
                     IHGDKGQQQRTDTLEAFKSGKLRVLVATDVAARGLDIDELPFVINFELPHTAEDYVHR
                     IGRTGRAGHHGYAISLVSSEEKHWLSEIEKLIKLQIPQEVVPGFDPDPDFHEAGSRAH
                     RGRRQAAAAADTEARAPAPRSGSRERGAERGGEGRREPARERDGLRAGPRRGRSTVAA
                     DGFDFSKPYEPVNPPVVAAEPTQPTAAAAGKPDPLRRHQRPIAVLLGGLGRK"
     gene            complement(5972..7066)
                     /gene="rlmM"
                     /locus_tag="P5537_09170"
     CDS             complement(5972..7066)
                     /gene="rlmM"
                     /locus_tag="P5537_09170"
                     /EC_number="2.1.1.186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (cytidine(2498)-2'-O)-methyltransferase
                     RlmM"
                     /protein_id="HRV78251.1"
                     /translation="MNQHTPAAALACAGLLGYCRAGFEKELAAELDDIAAEAGLIGYV
                     RAEPDSGYVIYETFEPTPLGSFGEATDWRRPVFARQLLPWFARVEDLPERDRATPIVD
                     AVKASGQRFSGVMLETPDTDEAKQRSGFCKRFTEPLAKALEKAGCLRSSRAGLPVLHV
                     LFTSATTAWLAAGQPGQCSTWPMGIPRLRMPSNAPSRSTAKLSEAFMTLLEEGERDSI
                     LRAGQRAVDLGAAPGGWTWQLVHRGLRVTAIDNGPLRDSVMATEMVEHLKADGFTWRP
                     HRPVDWMVCDMVEQPSRIASLVAEWVATGRCRYTVFNLKLPMKRRVEAVEQCRELIRK
                     RLASVGPYDLRIKHLYHDREEVTAFLTLKR"
     gene            7488..8525
                     /locus_tag="P5537_09175"
     CDS             7488..8525
                     /locus_tag="P5537_09175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004317119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HRV78252.1"
                     /translation="MEYRRLGGSGPRVSAVCLGTMTFGQQNGEAEAHSQLDLAVERGI
                     DFIDTAEMYPVPARAETSGETERIVGNWLARQAREKLVIATKVAGPARSLEWIRGGPL
                     ALDRANIRAAVEGSLRRLRTDYIDLYQLHWPARNQPLFGQLPFDPARERDCTPIRAQL
                     EALAELVEEGKIRHVGLSNEQPWGLMEFVRLARDSGLPRVVSVQNAYNLLNRVYEYGM
                     SEITLREDVALLAYSPLAFGHLSGKYLADPAAHGRLTEFENFGVRYAKPGVRAAVERY
                     AEIARRRGMSLTALALAFVYSRWFVGSTIVGATSVAQLAENLDAWHRRLDEDTLAEIE
                     QVHQLHANPAP"
     gene            complement(8538..8900)
                     /locus_tag="P5537_09180"
     CDS             complement(8538..8900)
                     /locus_tag="P5537_09180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004371997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78253.1"
                     /translation="MPRPTPSRSLRHLVLLALLPFAAGCDQLAEVLELPNPSKVEAEG
                     RAVGSACRHAGRSLEDCYSLNPGASKAAVFAGWRDMNDYMMEHKLEVVPSQLVPGTPP
                     TAAARTTPAGTPPASAAH"
     gene            9086..10348
                     /locus_tag="P5537_09185"
     CDS             9086..10348
                     /locus_tag="P5537_09185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004317123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HRV78254.1"
                     /translation="MNKMRFKALAAAVAVGGLFFAPGSVAQASAQQQVQLFHRLPDAK
                     AAALKDLVARFNAQSKDVQVVLSAADWRSGAPHLMILEGDDEEEFIAGKPRFKPLHQL
                     MKESGVPLKTLRPPAMMTRTPVDAKGQLLALPVGLSTPVLFLNRDALRQAGLNPDTTR
                     INTWFELQETLGRLADTGHTCPYTVAEPGRVMVENLSAWHNEPVATQSGKTTVPSFNG
                     MFQVKHVAMMASWTRARYLHVFNQQSEAEQRFASGECAVIAAPSASWTDYRRAGKVDV
                     AVSKLPYYDDFPGAPQNTIADGPALWASAGKKPAEYKAVARFVSFWLQPDNQVAWQRE
                     TGYLPLNRAGLLASRSELLGHDLENVQVAVDQLASKPATPQSSAQPVVDREKVRRILD
                     EELAGVWADQKAAKEALDNAVTRARNGN"
     gene            10445..11413
                     /gene="ispB"
                     /locus_tag="P5537_09190"
     CDS             10445..11413
                     /gene="ispB"
                     /locus_tag="P5537_09190"
                     /EC_number="2.5.1.90"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004317124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="octaprenyl diphosphate synthase"
                     /protein_id="HRV78255.1"
                     /translation="MSVQQLFAPIAADMQAVDTVIRNRLHSDVALIRRIAEYIVGSGG
                     KRLRPALVLYAAGALGYRGVHHHELAAVVEFIHTASLLHDDVVDESDLRRGKRTANAA
                     FGNASAVLVGDFLYSRAFQMMVGVNEMRVMRVLADATNIIAEGEVLQLLNCHNADVVI
                     DDYLRVIRYKTAKLFEAAARLGGIVAGADDALEQRLADFGMHLGTAFQLIDDVLDYSA
                     DEADTGKHLGDDLAEGKPTLPLIHVMQHGTAEQAALVRHAIEGGGRDDFAAVLAAIQS
                     SGALEETRRYAEAEAKLAIDAISVLPPSNYKEALLQLSDFAVRRKH"
     gene            11459..11535
                     /locus_tag="P5537_09195"
     tRNA            11459..11535
                     /locus_tag="P5537_09195"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11493..11495,aa:Pro,seq:cgg)
     gene            11635..11802
                     /locus_tag="P5537_09200"
     CDS             11635..11802
                     /locus_tag="P5537_09200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78256.1"
                     /translation="MRFILFVLILLGMIFLLASIRKGVRAGAGLTLGVILSGLGFVAL
                     LLLLLVVGGLF"
     gene            complement(11823..12794)
                     /locus_tag="P5537_09205"
     CDS             complement(11823..12794)
                     /locus_tag="P5537_09205"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HRV78257.1"
                     /translation="MTESPAPPATQPRSTSSPTAHVSARSVAAACAASGRFALAIIGP
                     GALGLHFAARLEGVVPVALIARDAAAAARLRAGVEVDGRGFRPQAFGPEQAPEADWVI
                     VLVKAGDTATAAATASRMRPLGVLSLQNGLTGELLRAHCAAPRVDQGITTEGAYRERG
                     DRGDRVHPSGAGETLVPPGFEAVAELLVRAGLRARVAPDIAHARLAKLLVNAAINPLA
                     ALFRVPNGALLDPPHRVLLDTLVREALPVLRAQGLDLDEAAALARVHAVAHATATNRA
                     SMLQDMLAGRRTEIDAITGALLRMAADRAVDLPAHRAVHTLVCALEP"
     gene            13055..14254
                     /locus_tag="P5537_09210"
     CDS             13055..14254
                     /locus_tag="P5537_09210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porin"
                     /protein_id="HRV78258.1"
                     /translation="MQNKLSSHRHARPAITAALPAAVAAALLALAATPVNAIGFSQGD
                     ATLDINGTVNGFYSHRTEERAGVKTTDSALTNGLLPGWINFVFTTKVEGLDIKAHVGF
                     APGINDKSDVVGLPSDPSCGGGTGCDSPFTQIDTRNLYFQFGNAEWGTVKLGRDIGLF
                     GQKIILSDMTLLGLGGNSYASTPFNTTFGMIGHGYMYTGFQPQITYTTPALGGFSASA
                     GIFDPNKFAGDETKDPGFQAMANYDWASGAAKGSLWAGAIHQRTSGAGSFNASGFELG
                     AKIGIGAFEAVAYGFDASGLGLSTVGALYLSPFGKTDGKGYFVQTTYTVGKTKFGINF
                     GENRDSGGALADTNKFRSATVGVYHSLNKYITLVGEYNQEKGDGDDLFAGDLKTRTIS
                     VGGILMF"
     gene            complement(14332..15657)
                     /locus_tag="P5537_09215"
     CDS             complement(14332..15657)
                     /locus_tag="P5537_09215"
                     /inference="COORDINATES: protein motif:HMM:NF025056.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003953 - NAD+ nucleosidase activity
                     [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HRV78259.1"
                     /translation="MWLERLQADDEEWVHGALTLAPGAASDWDPETRSTASRVLETLA
                     LVDQVTLSKRVVFAPAIGMTLTYQCMAPAAAAPSLEACLATLEKLGRQKGNVRVPTSP
                     ADFDPMLASSPSLQALVDSPRYRSGDTWIACPFRAAAAWAHMAATGAQIAEGDDAAHG
                     YQVNLYGFRPAPAQLREILLNRDRQDRLPALPARVLRQQHALVERARYGRWLSEEFLL
                     AGSEAAAAALRNSAVALFRKCYPGFDAGPEVSFSQDRCTDNLTLACSFDDACAADASY
                     VAAHAVDHETCLELLALDDDLPSLRPIRPAVTGRRYAFISYAHVDTARMLAVRGILDG
                     SGIETWHDTSIDGGEDWNAVLEGQIRNCSLFVLVLSPAAAASRIVRRELRFADALEKP
                     LLCIRLCETSLTDGLAMLLLPLQWIDADRPDSAERISTAARKLLQIRDV"
     gene            complement(15661..17301)
                     /locus_tag="P5537_09220"
     CDS             complement(15661..17301)
                     /locus_tag="P5537_09220"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78260.1"
                     /translation="MTRLTKALLLVGGVLLGLSQGYADDSCGYARDGACDEPLLCATD
                     TNGTDCAGVPAEVRAGAPTEAIEDAPLPLDESLPTQLWYPIEWAAWSLYLLPTHFGLD
                     PETTFVWLVIGGVILALYLRRKKGPASTETIRDLVWRAMSPDVRTGDVSEIAEARRQC
                     KHIAGALEKALGERNTKFRIYVDADAVSVPWLRVDCVIRDERGSFLTNLVMDFKPQPF
                     GMIPVLVDFEIDQLGRRRRITSAYEFGSEQIALMAACLGGASPPFRWTGARAREMPWQ
                     LTREQQRIALFEAPLMTSARAALKMIGLFAGLALALLAFGAAPAITILVGLGAYLAYR
                     HFHVPPPNYRIVAACPPHPPRDLRGLDSWQTVVRDLGEQRDVVLDRFEAMLADRFSDA
                     SEPISIRRENIWYSGAEDKVERQQLALTLRRAIVFVRIDRYGRDLFVGWDAHVNLLSW
                     KDRALQKGYQDGDGLKVELVGIETQYHQINEYDITDANFLLEATHTHLSSLVKDVLRE
                     REIDQEVDFSIVRESRQKLIEASPSAANGSRRRFFRKS"
     gene            17607..19127
                     /locus_tag="P5537_09225"
     CDS             17607..19127
                     /locus_tag="P5537_09225"
                     /EC_number="1.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011286773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HRV78261.1"
                     /translation="MLYALPGQADAKLQYKTRYDNFIGGQWVAPVKGQYFDVVTPITG
                     QKYTQAARSTAEDIELALDAAHAAFPKWGKTDATTRSNILLKIADRLEANLELLAYAE
                     TVDNGKPIRETLNADIPLAVDHFRYFAGCLRSQEGGISEIDENTMAYHIHEPLGVVGQ
                     IIPWNFPILMAAWKLAPALGAGNCVVLKPAESTPISILVLMELIADLLPPGVLNIVNG
                     YGREAGMPLATSKRIAKIAFTGSTSTGRVIAQAAANNLIPATLELGGKSPNIFFADVM
                     DKDDAFLDKAIEGLVLFAFNQGEVCTCPSRALIQESIYDRFIERAVKRVAAIKQGSPL
                     DTDTMMGAQASAEQMSKIQSYLQLGKEEGAQVLIGGARAQLDGDLADGYYIQPTLFKG
                     HNKMRIFQEEIFGPVLAVTTFKDEAEALSIANDTLYGLGAGVWSRNGNVAYRMGRAIQ
                     AGRVWTNCYHAYPAHAAFGGYKESGIGRETHKVMLDHYQQTKNLLVSYSENKLGFF"
     gene            19218..19598
                     /locus_tag="P5537_09230"
     CDS             19218..19598
                     /locus_tag="P5537_09230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF779 domain-containing protein"
                     /protein_id="HRV78262.1"
                     /translation="MVERVIATPAALELIEQLKAGHGPDLIFHQSGGCCDNSAANCYL
                     PTDLTIGPYDVHLGEIGGVPFYISASQYEYWKHTQLIIDVVEGQGGTFSLEGGTGKAF
                     HTRSRLYDDAEMAAVEAEDRALGR"
     gene            19790..21820
                     /locus_tag="P5537_09235"
     CDS             19790..21820
                     /locus_tag="P5537_09235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HRV78263.1"
                     /translation="MVDNTVHAAQAAVIESLRRQFSASGQVPDAGLPVPVLRSWARCQ
                     RLGLDMGERVRPPSTTRGDLMVARERSAALLAHASGVMEHLHEQIRSSGSMVLLADAS
                     GMILHGIGDPAFVDRASRVVLQAGANWSECERGTNAIGAALIERAPVEVLGAEHYLDC
                     NGVLTCSAAPIFDWRGELLGALDISGDHRSHQPHTLGLARMGVRLVERRLFESEHARH
                     ALLSFHPRPEGVGGLQEGLLAIDADGEIVAADRQARALLGTDERRAVGLGNFSNLFRG
                     GFGTLIGRVSRDPAALIELELRSGARVHVRVRVSPAWQVGVHAAPAGPARVVAAPDPS
                     RSARGGVTLETLSTGDPALQFALDRCARIVGRSIPILIQGESGSGKELLARACHNSGP
                     RADGPFVAVNCAAIPENLIESELFGYVGGAFTGARKEGAIGRIQQAHGGTLFLDEIGD
                     MPLAMQARLLRVLQERCVQPVGAGTAVPVDIALLCATHRQLGEQVKAGRFREDLYYRV
                     NGLSVQLPPLRARSDLQRIVRRLLDGSSHHPEPARIDLAPETMAILAAYPWPGNIRQL
                     QNVLEVALALLDEGETSILPLHLPEEVLQAAGEAPPRSASPLSPTPLSERVARPVRLA
                     DDPELFPLRRARALDDEAIRAAIARFDGNLSAAARHLGVARNTLYRRMGRPF"
BASE COUNT         3385 a         7343 c         7677 g         3376 t
ORIGIN      
        1 gcgacggcac cgagcagact accggcacgg tgacgatcgt cgtcgaggcc tcggtccaga
       61 ccgagcgcat cggcgatgcg ccggcgcggg tgacgagttc ggcccagttt gctactgcgt
      121 ggagcgatcc gctgctgcac ggcattcgcc atacggccga cgccgactcc ctcgcgccga
      181 cttggtccgc cgtgacgttc ggaacgatta acaacggggt tctgtctggt ggagatatct
      241 atacgggcga tcttggcgtc agcggccaga cggtggcttc gagcacggta cgacaggaaa
      301 tcgacggtac cgaggcgttg cgtttcgacc ttgctgcgca ggcgagcagc gtgaccgttg
      361 atctctcgcg tctctttgcc aacgacgacg gctcgatgct ttacgaggct ggacggctgc
      421 gcctgctgaa tggcaatgga gatgtggtcg ccgagactgt cttcgtcgct gactccacgc
      481 tcggccacaa gacggtttcg ctcgacagcg cgacggcgtt cagcacggtc gagctgagcg
      541 ccggcctcta tgacggtaca gatttcgtct ttggcgggta tgcggatgca gatggagagt
      601 tcgcctcccc ggcgtccgcg gatgcgttgg gaaatgcgca cggcagcgag ttcctggtcg
      661 actggatcga ggtcgatttc caggtgccgc tcgtgggcgt cggtgatccg ctttcgatct
      721 gaactgtcgg aactttttac agagacactg ctggtgtatt gcaagtaact gaaaacaatg
      781 aacttcaatg attggcacgg ttttcgctac tgcaatacgc cagctttcag aatagaggga
      841 accaggatga atgcagtcaa ttgcggtgga ccgttgatcc gcagcctgtt tgtggcagga
      901 ttgatcgcca cggcgccgat ggcgagtgcg gcagaggtgc tggtgagcca gccgttcaag
      961 aacggggggc cgagctactt gtccgatctg ggtggcgcgg tcaacgcgga ttcgttcaat
     1021 ttgagtggct cggccaacgt ttccgcgatt gcttggtggg gaacgcatgt cgatgaccag
     1081 cagctaggag ggttttcggt tcgactggca gagacacttg atgccttgct cgataactcg
     1141 agcgcactgg gcggaagtgt gagccgtggc gacgacgctg tcggtgagga cgatgagcca
     1201 tcacccgatg ggccgcgcaa actacatcgt ttccagctgg atctcactgc tccccttggc
     1261 tctctagggg ggaattacta ccttgcgatc ggtaacgaga cggtggaatg gttttgggcg
     1321 actggaaccg agggggattt gaagagtttc tacctcgaca ctgggaaccc gaacctgccg
     1381 gcagcctggg ctgaggacga caccaccgac atgtcgttcg aggtgatcgg cgaacgtcag
     1441 accgtgcccg agcccggcat cctcgcgctg ctcggtctag ccggcatcgg tggcctgctc
     1501 gcgcgtcgtc ggcgtcgttg aggcgttgca cccgagccga gcggtagccc ggttcggaaa
     1561 attcgcgcct gctgccgctc ctacatcccg tccggaccgc gacggttcat gtaggagcgc
     1621 cggcaggcgc gaatgcggcg gtggannnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1741 nnnnntccgg accgcgacgg ttcatgtagg agcgccggca ggcgcgaatg cggcggtgga
     1801 atgcgggccg tgcgcctcgg agccgccggg ttcgccgctg ccgcagctcc tacatcccct
     1861 ccggaccgcg acggttcatg taggagcgcc ggcaggcgcg aatgcggcgg tggactgcgg
     1921 gccgcgctcc tcggagccgc cgggttcgca gctgccgcag ctcctacatc ccctccggac
     1981 cgcgacgccc ctgtaggagc gccggcaggc gcgaatgcgg cggtggaatg cgggccgtgc
     2041 tcctcggagc cgccgggttc gcagctgccg cggctcctac aacccgcctg gaccgcgacg
     2101 cccctgtagg agcgccggca ggcgcgaatg cggcggtgga gtgcgggccg cgctcctcgg
     2161 agccgccggg ttcgcagctg ccgcagctcc tacaacccgc ctggatcgcg acgcccttgt
     2221 agaagggccg gcaggcgcga atgcggtggt ggaatgcggg ccgcgctcct cggagccgcc
     2281 gggttcgcag ctgccgcagc tcctacatcc cctccggacc gcgacgcccc tgtaggagcg
     2341 ccggcaggcg cgaatcttca gggatgtcgc cggacgcggt cgccaccgcc cgcggccgcg
     2401 atcgcggccg cgaactcgcg tgccgccagc ggccgcccga acagcgggcc ttgctgcaga
     2461 tggcagtcga gcgcgcacag gaaggcctgc tggccgcggt tctcgacccc gcgcgcgtag
     2521 atctccagcc ccagggtgcc ggcgaacgcg ccgaccgcct cgacgatggc ctcgctgtcc
     2581 tcgctgcggc cgaccccgcg caccagctcg gggtcgagct tgagcgcggc gagcgggtag
     2641 cggcgcaggc gcgggatgga cgacaggccg cgaccgaagt cgtcgatcga caggcgcacg
     2701 ccggtggcgg cgatgcgctc gagggtggcg gcgagcgtcg ggctgtcgag cgcgagcacc
     2761 ttctcgtcga ggtcgagctc cagccgatcg gccttcagtc cggacgcgcg cagcgcggtg
     2821 gcgacgcgga cggcaaagtc gccgcgcatc aactgttcca ccgcgacatt cacggtgagg
     2881 cgcaggcgcg tgccatcgtg cgccggcggc cagtcggcgg cgtggtggca ggcagtggcc
     2941 agaacccagt cgccgacgtc ggcgagcagg cgggggtcgc cgactgcatt catgaactgg
     3001 cggtagggca gcacgccgaa ctcggggtgg cgccagcgca gcaaggcctc gccggcacgg
     3061 gtgcggccgg agcgcgcatc gaccagcggc tggaagtgca gggtgagctc gtcggcctgc
     3121 aaggcgtggc gcaggccgcg ttcgagctgg ctgctgtcga agccggggcc gtcgaggcgg
     3181 gtgtggaagg cgctgcaacg gttgccgccg agccggcgtg cctgttcgag cgcgctcctg
     3241 gcgttgcgca gcagggtgtc gaggttgcgc ccgtcctgcg gatagagggc gaggccggcg
     3301 ctggcggtga tccgctgcgg ccccccgccg agctcgaagg gttccgcgac cgcgcgcagc
     3361 aggccttcgg cgaactggtc ggcattgccc ggatgttcgg ggtcgggtag gagcacgatg
     3421 aagctgtcgc tgcgctcgcg cgccaccagg gcctcgggtc cggccgcggc tgcgagccgt
     3481 cgcgcgatgc ggcgcaggac ctcgtcgccc gcgctctcgc ccaggctgcg attgaccgcg
     3541 ccgaagccgt cgaggtcgag gcgcgcgatc gcgatgctgc cgtggcggcc ggcggcgcgc
     3601 accgcgcagt cgccgaagcg cgcctcgagc atgcggcggt tggccagacc ggtgagcggg
     3661 tcgtggctcg tcaggtacat cgacatcgat ggcgcgtcgt cgaatacgtg tctggcccca
     3721 gccgtcgggc ttgcggctgt gaggtcggga tccctcgttg cgtcctcctc cgtggctgcg
     3781 ggcgggctca ggatgatcgc gtggatgccg ggccgcagcc gcggcgcgca gttgaactcg
     3841 agcgtgcgca cgccgccatc ggggagggcg aaatcgaggc ggccgcggcg ttcgccctcg
     3901 atcaggaggc gcgcgcgcgc ggcgaggaag gcctggccgt cggggaaaag gttggcgagc
     3961 ggacgcccgg cgacatcgcg gtagtcgcgg ccgagcaggc ggcaggccgc gctgttggcg
     4021 tcgagcacga cctcgtcgcc ggtgatgagc aggccctcgt cgagcagctc gagcagggcg
     4081 aggtaaacgc cggcctcggc accctccgag aggtccgcga cgaagggctc gacaggggag
     4141 gggccggggg agggcggcag gcccggcggg cgtccggaag ggttcacgac ggcgtggaag
     4201 cgcaggggaa gtcggtgcag gcaccccggg gagggggcct gcaagtgagg tcacagcata
     4261 gccgatgcct gcattccgcc gtgcggcgaa tagggggcgc cggcggccct tatttgcgcc
     4321 cgaggccgcc gagcagcacc gcgatcgggc gctggtggcg gcgcagcggg tcgggcttgc
     4381 cggccgccgc ggcggtgggc tgggtcggct cggcagcgac gacgggcgga ttgaccggct
     4441 cgtagggctt ggagaagtcg aagccgtcgg cggcgaccgt ggagcggccg cggcgggggc
     4501 cggcgcgcag gccgtcgcgc tcacgcgccg gttcgcggcg gccctcgccg ccgcgttcgg
     4561 cgccacgttc gcggctgccg gagcgcggcg ccggggcgcg tgcctcggtg tcggcggctg
     4621 cggcggcctg cctgcgcccg cgatgggcgc ggctgccggc ctcgtggaag tcggggtccg
     4681 ggtcgaagcc cgggacgacc tcctggggga tctgcagctt gatcagcttc tcgatctcgg
     4741 atagccagtg cttctcttcc gagctcacca gcgagatcgc gtagccgtgg tggccggcgc
     4801 ggccggtgcg gccgatgcgg tgcacgtagt cctcggcggt gtgcggcagc tcgaagttga
     4861 tcacgaaggg cagctcgtcg atgtcgagcc cgcgcgcggc cacgtcggtg gcgaccagca
     4921 cgcgcagctt gcccgacttg aaggcctcga gcgtgtccgt gcgctgctgc tggcccttgt
     4981 cgccgtggat ggcgtcggcc gagatgccgc tgcgctcgag gtagtgggcg agccgtccgc
     5041 acatcagctt ggtgtcgacg aagaccaggg cctgggtgtc gggcttgtgg cgcagcaggt
     5101 gggcgagcag gttgcgcttc atgcccgagg acaccgggtg caccacgtgg gtgatggtct
     5161 ccgacaccat gttgcggcgt gccacctcga tcagctgcgg gtccttcagc atctggtcgg
     5221 cgaggcgctt gatctcgtcc gagaaggtgg ccgagaacag caggctctgg cgctgcttgg
     5281 gcagcagggc gaggatgcgc ttgatgtcgg ggatgaagcc catgtcgagc atgcggtcgg
     5341 cttcgtcgag caccagcacc tcgacctgcg acaggttgat cgacttctgc tcgatgtggt
     5401 cgagcagccg ccccggcgtg gcgatgacga tctcgatgcc gcggcgcagc tcggcctgct
     5461 gcgggcggat gtcgacgccg ccatacacgc acaccgagcg cagcggcagg tgcttgctgt
     5521 aggtcttgac cgactcgaac acctgcatgg ccagttcgcg cgtgggcgcg aggatcagcg
     5581 cgcgcgtctg gtggcgggcg ggcgaggtgc tggtgttggc gtggcgggcg atgcggtgca
     5641 gtagcggcag cgtgaagccg gcggtcttgc cggtgcccgt ctgggcgccg cccatgacgt
     5701 cgtggccggc aatgacggtc gggatggcct ggcgctggat gggcgtgggc tcggtgtagc
     5761 cggcgtcggc gacggcctgg agaagttcgg gaatgaggcc gagatcggca aagctcatgg
     5821 gtgccttcgg gttgtagacg gtcgacgcac gaccgccgga tttcggaaaa cccggattat
     5881 acacggcgca aaaagcgtta ccggacaggg gcttcggtcg ccgcctcggt gggagcgggc
     5941 tggcccgcgc atccggtgcc tggcggcgcg ctcagcgctt gagcgtgagg aaggcggtga
     6001 cctcctcgcg gtcgtggtag aggtgcttga tgcgcaggtc gtaggggccg acgctggcga
     6061 ggcgcttgcg gatgagctcg cggcactgct cgaccgcctc gacgcggcgc ttcatcggca
     6121 gcttgaggtt gaagacggtg tagcgacagc gcccggtggc gacccactcg gccaccagcg
     6181 aggcgatgcg cgagggctgc tcgaccatgt cgcacaccat ccagtccacc ggccggtgcg
     6241 ggcgccaggt gaagccgtcg gccttgaggt gctcgaccat ctcggtggcc atcacgctgt
     6301 cgcgcagcgg gccgttgtcg atcgcggtga cgcgcaggcc gcgatgcacg agctgccagg
     6361 tccacccgcc cggcgcggcg ccgaggtcta ccgcgcgctg gccggcgcgc aggatgctgt
     6421 cgcgctcgcc ctcctcgagc agggtcatga aggcctcgga gagcttcgcg gtggagcggc
     6481 tgggcgcgtt cgagggcatg cgcaggcgcg ggatgcccat cggccaggtc gagcactgcc
     6541 cgggctggcc ggcggcgagc caggcggtgg tggcgctggt gaacagcacg tgcagcaccg
     6601 gcagcccagc gcggctgctg cgcaggcagc cggccttctc gagcgccttg gcgagcggct
     6661 cggtgaagcg cttgcagaag cccgagcgct gcttggcctc gtcggtgtcg ggggtctcca
     6721 gcatcacgcc cgagaagcgc tggccgctgg ccttgaccgc gtcgacgatc ggcgtggcgc
     6781 ggtcgcgctc gggcaggtcc tccacgcgtg cgaaccaggg cagcagctgg cgcgcgaaca
     6841 ccgggcggcg ccagtcggtg gcctcgccga agctgccgag cggagtgggc tcgaaggtct
     6901 cgtagatcac gtagccggag tcgggctcgg cgcgcacgta gccgatcagg ccggcttcgg
     6961 cggcgatgtc gtcgagttcg gcggcgagtt ccttctcgaa gccggcgcgg caatagccga
     7021 ggaggccggc gcaggcgagc gcggcggcgg gggtgtgctg gttcatgggg tcggtgcgcg
     7081 caggggctgc agtatgatgg gtccgcaccg ggccgcgcgg gcggcggccg gaaacggagc
     7141 aaggcagcgg atgataagcc gcgagcgccg cgctggcgag catggcgctc gcacccgccg
     7201 ccgccttcgc gcctgccggc gctcctacag gaggttgccg cgcgatggct cgtgtaggag
     7261 cgccggcagg cgcgaaggca gagacctccg aggcgcccgg gtccatgtag gagcgccggc
     7321 aggcgcgaaa acggcggtcg ggcccgggac gcgcgtcgat taccggaccg ccgcgttcgc
     7381 agctgccgca gctcctacag gccgtccggg acgcgcggtg gttcatgtag gagcgccggc
     7441 aggcgcgaat atgtccaaac agggagtcga ggatgacagc acgtgagatg gagtaccgcc
     7501 gactgggcgg gtcggggccg cgggtgtcgg cggtgtgcct ggggacgatg accttcggcc
     7561 agcagaacgg cgaggccgag gcgcacagcc agctcgacct cgccgtcgag cgtggcatcg
     7621 acttcatcga caccgccgag atgtatccgg tcccggcgcg tgccgagacc agtggcgaga
     7681 ccgagcgcat cgtcggcaac tggctggcgc gccaggcgcg cgagaagctg gtgatcgcga
     7741 ccaaggtggc cgggccggcg cgcagcctgg agtggatccg cggcggtccg ctcgcgctcg
     7801 accgcgccaa catccgcgcc gcggtcgagg gcagcctgcg ccggctgcgc accgactaca
     7861 tcgacctgta ccagttgcac tggccggcgc gcaaccagcc gctgttcggc cagctgccct
     7921 tcgatccggc gcgcgagcgc gactgcacgc cgatccgcgc ccagctcgag gcgctcgcgg
     7981 agctggtgga ggagggcaag atccgccacg tcggcctgtc gaacgagcag ccctgggggc
     8041 tgatggagtt cgtgcgcctc gcccgcgaca gcggcctgcc gcgcgtggtg tcggtgcaga
     8101 acgcctacaa cctgctcaac cgggtgtacg agtacggcat gagcgagatc acgctgcgcg
     8161 aggacgtcgc gctgctggcg tattcgccgc tcgccttcgg ccacctgtcg ggcaagtatc
     8221 tcgccgaccc ggcggcgcac gggcgcctca ccgagttcga gaatttcggt gttcgctacg
     8281 ccaagcccgg cgtacgcgcg gcggtggagc gctacgcgga gatcgcgcgc cggcgcggca
     8341 tgagcctcac cgcgctggcg ctcgccttcg tgtattcgcg ctggttcgtg ggcagcacca
     8401 tcgtgggggc gacctcggtg gcgcaactcg ccgagaacct ggacgcctgg catcggcgcc
     8461 tggacgagga cacgctcgcc gagatcgagc aggttcatca gctgcacgct aacccggcgc
     8521 cgtgaacgcc gcggcgatca gtgcgccgcg gacgctggcg gcgtgcccgc aggcgtcgtg
     8581 cgggcggccg cggtcggcgg cgtgcccggg acgagctgcg agggcacgac ctcgagcttg
     8641 tgctccatca tgtagtcgtt catgtcgcgc cagcccgcaa acactgccgc cttggaagcc
     8701 ccggggttga gcgagtagca gtcctcgagc gaacgcccgg cgtgacggca ggcgctgccg
     8761 accgcgcggc cctcggcctc gaccttcgaa gggttgggca attcgagcac ctcggcgagc
     8821 tggtcgcagc cggctgcgaa gggcagcagg gcgagcagca cgaggtggcg cagcgaccgg
     8881 gatggggtgg ggcggggcat ggcgatccgg ggggacgatc tactgtgcag attatcggct
     8941 gcgatcgtct gatcttgagc gcgtcgagtg tcgtgtgcgc ggcacgctcg ctccggacca
     9001 tcccccaaat cgatgacgcg cggctctata atcgcgcccg cttccgggcc gttctgcccg
     9061 gctccctttc gtgtgtgtcg attcgatgaa caagatgcgt ttcaaggcct tggctgcagc
     9121 ggtcgctgtc ggtggtctct tcttcgcgcc cgggtcggtg gcccaggcca gcgcccagca
     9181 gcaggtccag ctcttccacc gcctgcccga cgccaaggcg gcggcgctga aggatctggt
     9241 agcgcgcttc aatgcccagt ccaaggacgt gcaggtcgtg ctgtccgcgg cggactggcg
     9301 ctcgggggcg ccccacctga tgatcctcga aggggacgac gaggaagagt tcatcgccgg
     9361 caagccgcgc ttcaagccgc ttcaccagct catgaaggag agcggggtac cgctgaagac
     9421 cctgcgtccg cctgcgatga tgacgcgcac cccggtcgac gccaagggcc agctgctggc
     9481 gctgccggtg ggcctgtcga ccccggtgct gttcctcaac cgcgacgcgc tgcgccaggc
     9541 cggactcaac ccggacacca cccggatcaa cacctggttc gagctgcagg agaccctcgg
     9601 gcgcctcgcc gacaccggcc acacctgccc ctacaccgtg gccgaacccg gccgcgtgat
     9661 ggtggagaac ctctcggcct ggcacaacga gccggtcgcc acgcagagcg gcaagaccac
     9721 cgtgccgagc ttcaacggca tgttccaggt caagcacgtg gcgatgatgg cgagctggac
     9781 gcgcgcgcgc tacctgcacg ttttcaacca gcagtccgag gccgagcagc gcttcgcgag
     9841 cggcgagtgc gccgtgatcg cggcgccctc ggcgagctgg accgactacc gccgtgccgg
     9901 caaggtcgat gtggcggtgt ccaagctgcc ctactacgac gacttccccg gcgcgccgca
     9961 gaacaccatc gccgacggcc ccgcgctgtg ggcctcggcg ggcaagaagc cggccgagta
    10021 caaggcggtg gcgcgcttcg tgagcttctg gctgcagccc gacaaccagg tcgcctggca
    10081 gcgcgagacc ggctacctgc cgctcaaccg cgccggcctg ctggcctcgc gcagcgaact
    10141 gctcggtcat gacctcgaga acgtccaggt cgccgtcgac cagctcgcca gcaagcccgc
    10201 cacgccgcag tcgtcggcgc agccggtggt cgaccgcgag aaggtgcgtc gcatcctcga
    10261 cgaggaactc gccggcgtct gggccgacca gaaggccgcg aaggaagcgc tcgacaacgc
    10321 ggtgacgcgc gcccgcaacg gcaactgacg gcgtccatcc cccgcacgcg gcgcccgggg
    10381 cgcggcttga cgccgcgcgc gggcgccgcc taagatccac gacttttccg cgagccagaa
    10441 cgccttgtcc gtccagcagc tcttcgcgcc gatcgccgcc gacatgcagg cggtggatac
    10501 ggtcatccgc aaccgactgc actcggacgt ggccctgatc cgtcgcatcg cggagtacat
    10561 cgtcggcagc ggcggcaagc gcctgcgccc cgcgctggtg ctgtacgcgg cgggcgcgct
    10621 gggctatcgc ggcgtccatc accacgagct cgcggccgtg gtcgagttca tccacactgc
    10681 cagcctgctg cacgacgacg tggtggacga gtccgacctg cgccgcggca agcgcaccgc
    10741 caacgccgcc ttcggcaacg cctccgccgt gctggtcggc gatttcctct attcgcgcgc
    10801 cttccagatg atggtcgggg tcaacgagat gcgcgtcatg cgcgtgctcg ccgacgccac
    10861 caacatcatc gccgagggcg aggtgctgca actgctcaac tgtcacaacg ccgacgtcgt
    10921 catcgacgac tacctgcgcg tgatccgcta caagaccgcc aagctgttcg aggccgccgc
    10981 gcgcctgggc ggcatcgtgg ccggcgcgga cgacgcgctc gagcagcgcc tggccgactt
    11041 cggcatgcac ctgggcaccg ccttccagct catcgacgac gtgctcgact actcggccga
    11101 cgaggccgac accggcaagc atctcggtga cgacctcgcc gagggcaagc cgacgctgcc
    11161 gctgatccac gtgatgcagc acggcacggc cgagcaggcg gcgctggtgc gccacgccat
    11221 cgaaggcggc ggccgcgacg attttgccgc cgtgctcgcg gcgatccagt cgagcggcgc
    11281 gctcgaagag acgcgtcgct acgccgaggc ggaggcgaag ctcgcaatcg acgcgatttc
    11341 ggtgcttccc ccttccaatt acaaggaagc gctgctacaa ttatcggact ttgcagttcg
    11401 gcgaaaacac tgatatagtt tctggcttcg caggacagca aaaagcagta aaaagtgtcg
    11461 gggaatagct cagcctggta gagcactgcg ttcgggacgc aggggccgga ggttcgaatc
    11521 ctctttcccc gaccaccctt tcccggaaaa cgcccaagtg agtcgatcac ttgggcgttt
    11581 ccttttccgc ctgtccgtgc aagccgcagc gctggatcaa ggaggtcctc gaccatgcgc
    11641 ttcatccttt tcgtcctgat cctgcttggg atgattttcc tgctcgcgtc gatccgcaag
    11701 ggcgtgcgtg cgggggccgg cctgacgctg ggcgtgatcc tgtccggact cggtttcgtg
    11761 gccttgctgc tcctgctgct ggtggtgggc gggctcttct gaaccctccg atacgctcgc
    11821 gctcagggtt ccagcgcgca caccagggta tgcaccgcgc gatgggcggg gaggtcgacc
    11881 gcgcggtctg cggccatccg cagcaaggcg ccggtgatcg cgtcgatctc cgtgcgccgg
    11941 ccagcgagca tgtcctgcag catgctcgcc cggttggtcg ccgtggcatg ggcgaccgca
    12001 tgcacacggg cgagcgcggc cgcctcgtcg aggtccaggc cctgcgcgcg caacaccggc
    12061 agggcctcgc gcaccagggt gtcgagcagc acgcgatgcg gcggatcgag cagcgcgccg
    12121 ttcggcaccc ggaacagcgc cgcgagcgga ttgatggcag cgttgaccag caacttggcg
    12181 aggcgcgcgt gcgcgatgtc gggggcgacg cgggcacgca gccccgcgcg gaccaagagt
    12241 tcggcgaccg cttcgaagcc gggcggcacc agcgtctcgc ccgcacccga cggatgcacc
    12301 cggtcccctc tgtcaccccg ctcgcgatag gcaccctcgg tggtgatgcc ctgatcgacc
    12361 cgcggcgccg cgcagtgcgc gcgcagcagc tccccggtca gcccgttctg cagggatagc
    12421 acgcccagcg ggcgcatgcg gctggcggtt gccgccgccg tcgcggtgtc gcctgccttc
    12481 accagcacga tcacccagtc cgcctccggc gcctgctccg gtccgaaggc ctgcggccga
    12541 aaacctcgcc catccacctc gacgccggca cgcagccgcg ccgccgccgc cgcgtcgcgt
    12601 gcgatcagcg cgaccggaac gacgccttcg aggcgggctg cgaagtgcag gcccagtgcg
    12661 ccgggtccga tgatggcgag cgcgaatcgg cccgatgccg cgcacgcagc tgcgacgctg
    12721 cgcgccgaga cgtgcgcggt tggggaggac gtcgatcggg gctgtgtggc cggcggggcg
    12781 ggggactctg tcatcgaagc ggagatcctg tcaggggcga gcggaccgga atgaggccgg
    12841 tgggccgtgg tgtgcgcgtg ctccggcggt gccgttccga agcagcgcgg gcatggattg
    12901 tggagcatcc ggagcgggct gtgcggccgc gcggcgcatg aatgcccgga tcggggcgtt
    12961 ttctcgggtg tggcacagcg tttgcgcagc ccgttctcga tccgtccgcc acgcggacgg
    13021 gtcgacggca tccataccat ccgaggggac atccatgcaa aacaagcttt ccagccaccg
    13081 ccacgcccga cccgccatca ccgccgcgct gccggctgcg gtggcggctg cgctgctcgc
    13141 gctcgccgcc acgccggtca atgcgatcgg tttctcccag ggcgacgcca cgctcgacat
    13201 caacggcacg gtcaacggct tctactccca ccgcaccgag gagcgtgcag gcgtcaagac
    13261 gaccgactcc gcactcacca acggattgct gccgggctgg atcaacttcg tgttcacgac
    13321 caaggtggaa ggtctggaca tcaaggccca tgtcggcttc gcgcccggca tcaacgacaa
    13381 gtcggacgtg gtcggcctgc ccagcgaccc gagctgtggt ggcggcaccg gctgcgacag
    13441 ccccttcacc cagatcgaca cccgcaacct gtacttccag ttcggcaacg ccgaatgggg
    13501 cacggtcaag ctcgggcgcg acatcggcct gttcgggcag aagatcatcc tgtccgacat
    13561 gaccctgctc gggctgggcg gcaacagcta cgcgtcgacg cccttcaaca ccaccttcgg
    13621 catgatcggc cacggctaca tgtacaccgg cttccagccg cagatcacct acaccacgcc
    13681 ggccctcggc ggcttctcgg cctcggcggg catcttcgat cccaacaagt tcgccggcga
    13741 cgagaccaag gaccccggct tccaggcgat ggcgaactac gactgggcgt cgggcgcggc
    13801 gaagggctcg ttgtgggcgg gggcgatcca ccaacgcacc agcggcgccg gcagcttcaa
    13861 cgccagcggc ttcgagctgg gtgcgaagat cggcatcggc gccttcgagg cggtcgccta
    13921 cggcttcgac gcgagcgggc tgggcctgtc gacggtcggc gcgctctacc tgtcgccctt
    13981 cggcaagacc gacggcaagg gctatttcgt gcagacgacc tatacggtgg gcaagaccaa
    14041 gttcggcatc aacttcggcg agaaccgcga cagcggcggc gcgctggccg acaccaacaa
    14101 gttccgctcc gctaccgtcg gcgtgtatca cagcctcaac aagtacatca ccctggtggg
    14161 cgaatacaac caggagaagg gcgatggcga cgacctcttc gcgggcgacc tgaagacgcg
    14221 gaccatctcg gtcggcggca tcctgatgtt ctgaggctag gacgcagggt tccggaattg
    14281 cggggcggca cgacgcgggc gcgccgccct ccgatggttc tgcccgggac atcaaacgtc
    14341 gcgaatctgc agcaactttc gtgctgccgt ggagatccgc tccgcgctgt cgggcctgtc
    14401 ggcatctatc cactgcagtg gcagcagcaa catcgcgaga ccgtccgtca gcgaggtctc
    14461 gcacaagcgg atgcacagca ggggtttctc gagagcatcg gcgaagcgga gctctcgccg
    14521 cacgatcctg gaggctgccg cggcagggct gagcaccagg acaaagagcg agcagttgcg
    14581 gatctgccct tcgagcacgg cgttccagtc ctcgccgccg tcgatactcg tgtcatgcca
    14641 cgtttcaatc ccgctgccgt cgaggatccc gcgcacggcg agcattctgg ccgtgtcgac
    14701 atgcgcgtag ctgatgaagg cgtagcggcg cccggtcacg gccggacgga tggggcgaag
    14761 cgacggcagg tcgtcgtcga gcgccagcag ttcgagacag gtctcgtgat cgaccgcgtg
    14821 cgcggcgaca taactcgcat ccgcagcgca cgcatcgtcg aacgaacagg ctagggtcag
    14881 gttgtcggtg cagcggtcct gcgaaaagct cacctcgggc cccgcgtcga aaccgggata
    14941 gcactttcgg aacagggcca ccgcgctgtt gcggagcgca gcggcggcgg cttcgctacc
    15001 ggccagaagg aactcctcgc tcagccagcg gccgtatcgc gcccgttcga cgagggcgtg
    15061 ctgttgtcgc aatacgcggg caggcaaagc cgggagccgg tcctggcgat cccggttgag
    15121 aaggatctcg cgcagttgcg cgggcgcggg acggaagccg tagagattga cctgataacc
    15181 atgcgctgca tcgtctccct cggcgatctg cgctcctgtc gcggccatgt gcgcccaggc
    15241 cgcggcggcg cggaacggac aggcgatcca ggtatcgccg gagcggtagc gcgggctgtc
    15301 gacgagcgcc tgcagcgaag ggctgctcgc cagcatcgga tcgaagtctg ccgggctcgt
    15361 cgggacgcgc acgtttccct tctgcctgcc gagcttctcg agcgtggcca ggcaagcttc
    15421 caggctgggg gcggctgcgg caggcgccat gcattgatag gtgagggtca tgccgatggc
    15481 gggagcgaag accactcgtt tcgacagggt gacctgatcg acgagggcca gcgtctcgag
    15541 gacccggctc gccgtgctcc gcgtttcggg atcccaatcc gacgccgcgc cgggtgcgag
    15601 cgtcagcgcg ccgtgcaccc actcctcgtc atccgcctga agacgttcga gccacatggt
    15661 tcaggacttg cggaagaagc gccggcgcga gccgtttgct gccgagggcg acgcctcgat
    15721 caatttctgg cgcgactcac ggacgatgct gaaatcgact tcctggtcga tctcccgttc
    15781 gcgcagcacg tccttgacga ggctgctcag gtgggtgtgg gtggcttcga gcaggaaatt
    15841 cgcgtcggtg atgtcgtact cgttgatctg gtggtactgc gtctcgatgc cgacgagctc
    15901 caccttcagc ccgtcgccgt cctggtatcc cttctggagc gcgcggtcct tccaggacag
    15961 gagattgacg tgcgcgtccc agccgacgaa cagatcgcgg ccgtagcgat cgatgcgtac
    16021 gaaaacgatg gctcgccgca aggtcagtgc cagctgctgg cgttcgacct tgtcttccgc
    16081 gccgctgtac cagatgtttt cgcgccggat cgagatcggc tcgctcgcgt ccgaaaacct
    16141 gtccgcgagc attgcctcga accgatccag cacgacatcc cgttgctcgc cgagatcacg
    16201 gacgaccgtc tgccaagaat ccagcccgcg caggtcgcgt ggcggatgcg gcggacaggc
    16261 cgccacgatg cggtagttcg gtggcgggac atggaaatgc cgatacgcca ggtaagcccc
    16321 cagtccgacc aggatcgtga tcgccggcgc ggcaccgaac gccagcaagg cgagcgccag
    16381 acccgcgaac aggccgatca tcttcagcgc cgcccgggcc gaggtcatca gcggggcctc
    16441 gaagagagcg atcctttgct gctcgcgtgt caattgccat ggcatctcgc gcgccctcgc
    16501 cccggtccag cggaacggcg gcgacgctcc gccgaggcag gctgccatga gcgcgatctg
    16561 ctccgacccg aactcgtatg cggaggtgat gcgcctgcgc cgccccaact ggtcgatctc
    16621 gaagtcgacg agaaccggga tcattccgaa cggttggggc ttgaaatcca tcaccaggtt
    16681 ggtgaggaag cttcctcgtt cgtcgcggat cacgcagtct acccgcaacc acgggacgct
    16741 gaccgcgtct gcgtctacgt agatgcggaa cttcgtgttc cgctcgccca gcgctttctc
    16801 gagcgctcct gcgatgtgct tgcactggcg ccgtgcctcg gcgatctcgc tcacgtcgcc
    16861 cgtccgcaca tccgggctca tcgctctcca caccaggtcg cggatcgtct cggtgctggc
    16921 gggccccttc ttgcgccgaa gataaagcgc gaggatcacg ccgccgatca cgagccagac
    16981 gaatgtcgtc tccggatcca ggccgaaatg ggtgggcagg agataaagcg accacgccgc
    17041 ccactcaatg gggtaccaga gctgtgtcgg caaggattcg tcgaggggca ggggggcgtc
    17101 ctcgatcgcc tcggtcgggg cgcccgcccg gacttctgcc ggcacgccgg cgcaatccgt
    17161 tccgttggtg tcggtggcgc acagcagcgg ttcatcgcag gcgccatcgc gcgcatagcc
    17221 gcaactgtcg tccgcgtatc cttgggagag gccgagaagt acccctccga ccaggagcag
    17281 agctttcgtc agacgagtca ttctcgatcc ctccggagag gattcatgtc ttcggtatag
    17341 cagagcacga tgcgttggcc agttcatcgt ccatgtgccc tgcggggcag tccgcatcga
    17401 cggcggtgcg cgccaccgtt cgtggagcac ctggagcaaa tggagcagtc cggatttgct
    17461 ccgaatgccc cacggagcgt ccggggcgtc cgtttgaaaa acgctaagtc gttgttgaga
    17521 aaggaggagg ctgtctggca cgggggctgc agggtgggtg tgtggcgaaa ccgcccgcaa
    17581 ccgaaaccac accaggagac gacaccatgc tgtatgcact gcccggccag gccgacgcca
    17641 agctccagta caagacccgc tacgacaact tcatcggcgg ccagtgggtg gccccggtca
    17701 agggccagta cttcgacgtg gtcaccccga tcaccggcca gaaatatacc caggctgcgc
    17761 gctccaccgc cgaggacatc gagctcgccc tcgacgccgc gcacgccgcc ttcccgaagt
    17821 ggggcaagac cgacgccacc acccgctcca acatcctgct caagatcgcc gaccgcctcg
    17881 aagccaacct cgaactgctc gcctacgccg agaccgtcga taacggcaag ccgatccgcg
    17941 agacgctcaa cgccgacatc ccgctcgccg tcgaccactt ccgctacttc gccggctgcc
    18001 tgcgctcgca ggaaggcggc atctcggaga tcgacgagaa caccatggcc taccacatcc
    18061 acgagccgct gggcgtggtc ggccagatca tcccgtggaa cttccccatc ctgatggcgg
    18121 cctggaagct ggcgccggcg ctgggcgcgg gcaactgcgt ggtgctcaag cccgccgagt
    18181 cgaccccgat ctcgatcctg gtgctgatgg agctgatcgc cgacctgctg ccgccgggcg
    18241 tgctgaacat cgtcaatggc tatggccgcg aggccggcat gccgctcgcc accagcaagc
    18301 gcatcgccaa gatcgccttc accggctcca cctccaccgg ccgcgtcatc gcccaggccg
    18361 ccgccaacaa cctgatcccg gccacgctcg agctgggcgg caagtcgccc aacatcttct
    18421 tcgccgacgt gatggacaag gacgatgcct tcctcgacaa ggcgatcgag ggtctggtgc
    18481 tgttcgcctt caaccagggc gaggtgtgca cctgcccgag ccgtgcgctg atccaggaat
    18541 cgatctacga ccgcttcatc gagcgcgcgg tcaagcgcgt cgccgcgatc aagcagggca
    18601 gcccgctcga caccgacacc atgatgggcg cgcaggcctc cgccgagcag atgagcaaga
    18661 tccagtccta cctgcagctc ggcaaggaag agggcgccca ggtgctgatc ggcggcgcgc
    18721 gcgcccagct cgacggcgac ctggccgacg gctattacat ccagccgacg ctgttcaagg
    18781 gccacaacaa gatgcgcatc ttccaggagg agatcttcgg gccggtgctc gcggtgacca
    18841 ccttcaagga cgaggccgag gccctgtcga tcgccaacga caccctgtac ggcctgggcg
    18901 ccggcgtgtg gagccgcaac ggcaacgtcg cctaccgcat gggccgcgcc atccaggccg
    18961 ggcgcgtgtg gaccaactgc taccacgcct acccggcgca cgcggccttc ggcggctaca
    19021 aggagtcggg catcggccgc gagacgcaca aggtcatgct cgaccactac cagcagacca
    19081 agaacctgct ggtgagctac agcgagaaca agctcggctt cttctgatca aggcgttctc
    19141 cctcccttgc ccgtgaagcg ggtgagcttc gcgggggcgg gcgaccgccc ccgtttttca
    19201 ttctggaggt tcatgacatg gtcgaacgcg tcatcgccac tcccgcggcg ctcgaactga
    19261 tcgagcagct caaggccggg cacggcccgg atctgatctt ccaccagtcc ggtggctgct
    19321 gcgacaacag cgccgccaac tgctacctcc ccaccgacct caccatcggc ccctacgacg
    19381 tgcatctggg cgagatcggc ggcgtgccct tctacatcag cgcctcgcag tacgaatact
    19441 ggaagcacac ccagctcatc atcgacgtgg tcgagggcca gggcggcacc ttctcgctgg
    19501 aaggcggtac cggcaaggcc ttccataccc gctcgcggct ctatgacgac gccgagatgg
    19561 cggcggtcga ggcggaggat cgcgccctcg gccgatagga tctcgcgatc gtcggatttt
    19621 tctccattgc tccacacttc ctgcgccgca cttgcggcat gatgcttgct tcagtcgttg
    19681 gacgagacgg ccgcggtccg atccccggag cggccgggac gacgatgaaa gagcccgggc
    19741 gatgcgtttc gagcgcaggc gcaccgcggc cgcaggtgga gacgagacga tggtcgataa
    19801 cacggtgcat gccgcgcagg cggcggtgat cgaatcgctg cgcaggcagt tttccgcgtc
    19861 cggccaggtg cccgacgcgg gcctgccggt tccggtgctg cgctcgtggg cgcgctgcca
    19921 gcgcctcggg ctggacatgg gcgagcgcgt gcgcccgccg agcaccacgc gcggcgacct
    19981 gatggtggcg cgcgagcgca gcgcggcctt gcttgcgcac gccagcggcg tcatggagca
    20041 tctgcacgaa cagatccgct cgtcgggcag catggtgctg ctcgccgacg ccagcggcat
    20101 gatcctgcac ggcatcggcg atccggcctt cgtcgaccgc gccagccgcg tcgtgctgca
    20161 ggcgggggcg aactggagcg aatgcgagcg cggcaccaac gcgatcggcg ccgccctgat
    20221 cgagcgtgcg ccggtcgagg tgctcggcgc cgaacactat ctcgactgca acggtgtgct
    20281 cacctgcagc gcggcgccga tcttcgactg gcgtggcgaa ctcctcggcg cgctcgacat
    20341 ctcgggcgac caccgcagcc accagcccca caccctcgga ctcgcgcgca tgggcgtgcg
    20401 cctggtcgag cgtcggctgt tcgagagcga gcatgcgcgc cacgcgctgc tctccttcca
    20461 cccgcgcccc gagggcgtcg gcggcttgca ggaaggcttg ctggcgatcg atgcggacgg
    20521 cgagatcgtc gccgccgacc gccaggcgcg agcgctgctg ggcaccgacg agcgtcgtgc
    20581 cgtgggcctg gggaatttct ccaacctgtt ccgcggcggc ttcggcacgc tgatcgggcg
    20641 cgtgtcgcgc gatccggcgg ccttgatcga gctcgagctg cgctcggggg cacgggttca
    20701 cgtgcgcgtg cgggtgagcc cggcctggca ggtcggtgtg cacgctgcac cggcgggtcc
    20761 ggcccgggtg gtcgcggccc ccgacccctc gcgctcggcg cgcggcggcg tcacgctcga
    20821 aacactctcg accggcgatc ccgcattgca gttcgcgctc gaccgctgcg cgcgcatcgt
    20881 cgggcgcagc atcccgatcc tgatccaggg tgaatccggc tccggcaagg agttgctcgc
    20941 gcgcgcctgc cacaacagcg ggccgcgtgc cgacggtccc ttcgtcgcgg tcaactgcgc
    21001 ggcgattccc gagaacctga tcgagtccga gctcttcggc tacgtcggcg gcgccttcac
    21061 cggtgcgcgc aaggaagggg ccatcggccg catccagcag gcccatggcg gcacgctttt
    21121 cctcgacgag atcggcgaca tgccgctggc gatgcaggcg cggctgctgc gcgtgctgca
    21181 ggagcgctgc gtgcagccgg tgggcgcggg caccgcggtg ccggtcgaca tcgcgctgct
    21241 gtgtgcgacc caccgccagc tcggcgagca ggtcaaggcc gggcgcttcc gcgaggacct
    21301 gtactaccgg gtcaacggcc tgagcgtgca gctgccgccg ctgcgcgcgc gcagcgacct
    21361 gcagcgcatc gtgcgccgcc tgctcgacgg cagcagccac catccagagc cggcgcgcat
    21421 cgacctcgcg cccgagacga tggcgatcct cgcggcctac ccctggccgg gcaacatccg
    21481 ccagctgcag aacgtgctcg aggtcgcgtt ggcgctgctc gacgagggcg agacgagcat
    21541 cctgccgctg cacctgcccg aggaggtgct gcaggcggca ggggaggcgc cgccgcgctc
    21601 cgcgtcgcca ctctccccaa caccgctctc cgaacgcgtg gcgcgccccg tgcgactcgc
    21661 cgacgacccc gagctgttcc cgctgcgacg cgcccgagca ctcgacgacg aggccatccg
    21721 cgccgcgatc gcccgcttcg acggcaacct ctccgccgcc gcccgccatc tgggcgtcgc
    21781 gcgcaacacg ctctacagga ggatgggacg gccgttctga ggcgcacggc agcccaggac
    21841 ccacagcgcc cgcccattcg cgcctgccgg cgctcctaca a
//
LOCUS       DAOTIN010000050        21611 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_2901_length_21611_cov_8.870199, whole genome shotgun sequence.
ACCESSION   DAOTIN010000050 DAOTIN010000000
VERSION     DAOTIN010000050.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 21611)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 21611)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21611
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2901_length_21611_cov_8.870199"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            152..2341
                     /locus_tag="P5537_09240"
     CDS             152..2341
                     /locus_tag="P5537_09240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018991810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HRV78264.1"
                     /translation="MSRAEMDVLGWDQCDVILVTGDAYIDHPSFGMALVGRLLEAHGF
                     RVGILSQPDWHSAEPFRALGRPRLYFGITAGNMDSLVNRYTSDRKIRSDDAYTPNAEA
                     GKRPDRAVTVYAQRAREAYPGTPIVIGSIEASLRRIAHYDYWSDKVRRSVLPDSKADI
                     LLFGNAERALVALTHRLDAGEPIESIRDLRGTAFMVKPGWKPAADWHELDSRALDKPG
                     RIDAHPDPYAMEPTAAAPKSAADGAQPVRIVPAAERLAARRADRARTVIRLPSYEEVK
                     DDPVMYAHASRVFHLESNPGNARALVQCHGEGPGARDVWINPPPVPLTTPEMDFVYDR
                     PFARAPHPIYGGARIPAWDMIKFSINIMRGCFGGCTFCSITEHEGRIIQSRSHESIIH
                     EIEEIRDKSPDFKGHITDLGGPTANMYRMACKSKAIEENCRRLSCVYPGICENLNTDH
                     SSLVELYRKARAVPGIKRITIGSGLRYDLAVRSPEYVKELVTHHVSGLLKIAPEHTEE
                     NTLSKMMKPGIGAYEEFRQMFEKFSAQAGKKQHLVPYFIAAHPGTTDEDMLNLALWLK
                     KNNFRLDQVQTFLPTPMALATTMYHSRKNPLKKVSADSEVVETARAGRIRKLHKAFLR
                     WHDPENWPLLREALIEMGRAELIGNGPHCLVPRQQPAQLVAAQAGGAREGAGRPASKG
                     REAGRAPGAAGRKGDAGGRGSAARGSPGGAGERKPGGCAKPRSRRGA"
     gene            complement(2338..4257)
                     /locus_tag="P5537_09245"
     CDS             complement(2338..4257)
                     /locus_tag="P5537_09245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHASE domain-containing protein"
                     /protein_id="HRV78265.1"
                     /translation="MLDRSTAAWLALVFGVLLTLVLWRYVGEHLEDRTRDRFANHAAL
                     ARDNLLSRMQAYEQVLHGGAALFAASDAVSRAEWGEYVAALHLERSLPGIQGTGFTAM
                     FPASALAAHVAEVRSQGFPDYDVHPPGSRAQYSSIVFLEPFDARNRRAFGYDMYSEPV
                     RREAMERARDTGRAALSGRVILVQEFGTEVQPGFLMYLPVYAKDRPLATVEERRAALL
                     GFVYAPFRALDMMQAIFRDDLRDAHIELHDLHESLQTLLYASAGHDRTARYVASHEVE
                     VAGRKWIASFGSTPAFEADHASAEPALILYGGSALSVMLFAVMHSNARHRRRMHAAAL
                     HLARSRDEFRTLVENVPGVVFRCQIEVPWKVMHISRGITLLTGATPDEFMSGRVTFGD
                     FILQEDVPAIVAAIENACACHANYEVEYRMRGRDGRIRWVSERGRVAVDVDDKPLRLD
                     GVIIDVTERKTAEEAIRNLAFVDTLTQLPNRRFLLDRLRQGLANARRHGRHGALLFID
                     IDHFKRVNDTYGHEAGDQLLCEIAARLRKAVREGDTVARLGGDEFVVMLEDLGEAAPE
                     AADKATLIADKILTDLNAPYDLGTVRHRSTPSIGIACFDGGEERAEDLLRRADEAMYR
                     AKAGGRNRLETQQAS"
     gene            4486..5742
                     /locus_tag="P5537_09250"
     CDS             4486..5742
                     /locus_tag="P5537_09250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0042953 - lipoprotein transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter permease
                     subunit"
                     /protein_id="HRV78266.1"
                     /translation="MPYELLVGLRYTRSRKRAQGRNRFISFISLVSMFGIALGVAALI
                     VVLSVMNGFQEELRTRILGVASHVQVQSPEGGLMAWQQVADESLRHPAVRAAAPYVQE
                     QGMLSFDEGVRGTLVRGVIPSAEDKVADFGRYMQAGSFDALQAGRFGIVLGRDLAAAL
                     RVRLGEKVTLIAPQGLVTPAAVLPRVKQFEVVGIFEAGMYEYDSSLALVHIADAQALY
                     RLGDAVSGVRLKLDDLFAAPRVARELAMTISEPGLVVADWTRSHANFFRAVALEKTMM
                     TLILFLIVAVAAFNIVSTLVMAVQEKYADIAILRTLGASPASIMAIFVLQGSVIGLVG
                     LAAGVAGGLAIAHNLDVVIPALETLTGATLWNKEIYYINELPSQVLWSDVSTIVTVSF
                     VLTLIAALYPSWRASKVNPAEALRYE"
     gene            5735..6436
                     /gene="lolD"
                     /locus_tag="P5537_09255"
     CDS             5735..6436
                     /gene="lolD"
                     /locus_tag="P5537_09255"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0042953 - lipoprotein transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter
                     ATP-binding protein LolD"
                     /protein_id="HRV78267.1"
                     /translation="MSEIPNSGAQPAVVACTGLSKHFREGAEAVRVLDGVELEVRRGE
                     RVAIVGSSGSGKSTLMHLLGGLDVPSAGSVRLMGQDFSTMSEAARGRLRNAALGFVYQ
                     FHHLLPEFSALENVAMPLYIRRVARAEADERAAQMLREVGLGHRLDHAPGELSGGERQ
                     RAAIARALVTQPACVLADEPTGNLDRRTAGAVFDLMLSLNERLATSFVIVTHDETLAA
                     RAQRTLRLVDGRLGG"
     gene            6545..8569
                     /locus_tag="P5537_09260"
     CDS             6545..8569
                     /locus_tag="P5537_09260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HRV78268.1"
                     /translation="MKILFQPAVRLLDRLSYPLKFGLIILVCAVASVILLVQIFTSLR
                     DEIRVTEREIAGLHLFDAGFGVILKTQQHRGLSAGVLGGSSELAPKREAKAAELRAAI
                     GALDAAIDGDAGWSGLRAGWQAQRGELVRLADSGLSMPGAENFRLHTATIAGLMRWLG
                     ELGDASGLSLDPEAASSNLLAPLLGALPELSERLGQLRARGTALSARRELSRSDEHAL
                     VALLAEIGRAESAVLERLRRTAAANASLAGSVDGMGREISEGVARVREATRQELLDQR
                     FGLSSTAFFDLVTGAIDTAVRNFDQVLRPEVGRLLAARLDRLNQRLNTQVAISVLGML
                     LAGYLFIGIYLAIVRSVRELSAGAQGFAAGDYRSRVDFSARDELAEVARQFNSMADHV
                     AGLIRDIQTGAAHVGSAATEMSASARRVLQGSETQSDAASSVAAAVEEMTRGVDGIAH
                     HASTAQQLAEDSGRLSQEGRSVMEQSVAEMERIAEAVDLSSEAIRELGEKSRQINAIV
                     DSIRDIADQTNLLALNAAIEAARAGETGRGFAVVADEVRKLAERTSLATREIGGMVAA
                     IQQGTERAVDTMQQGVQRVRDGVEMSNRAGSSMAQISAGADQVLTAVREISTALHEQS
                     LASNDIARNIERIADMTEHNSVTVRETAATAETLEQLSGTLREQASRFRV"
     gene            complement(8649..9206)
                     /locus_tag="P5537_09265"
     CDS             complement(8649..9206)
                     /locus_tag="P5537_09265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2062 domain-containing protein"
                     /protein_id="HRV78269.1"
                     /translation="MRKLFKRFLPDHRSVSENRWLRPFASTLLHPRLWHLNRHSAAGA
                     VAVGMFCGLIPGPFQMPGAALLCVLLRVNLPLALVTTLYSNPLTIVPLYVAAFAIGSQ
                     ISGDGEVDFVPPPEFAGFDPARWATDLAAWAGELGRPLVVGLIVLAASLSMVSYLAVR
                     WGWRLWLIRQWRQRRKRCDSLPARK"
     assembly_gap    9425..9524
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            9892..12309
                     /locus_tag="P5537_09270"
     CDS             9892..12309
                     /locus_tag="P5537_09270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HRV78270.1"
                     /translation="MRIIALGFLAGTLLVQNADTLDGLTVAGGLGVGAAVGLRLALAQ
                     GLLRVQATRRRVGIALTAFAALAAGVAWTAWRAEVRLGDELAGALEGVELRLRGRVAG
                     LPRASGPGWRFDFEVEPDTPGVPGLVQLGWRPEGGDADTNADSVAPRMLPMPRPGERW
                     ALTVRLWRPHGFANPASFDYEAWLLERGVRATGSVRGPGRLLDEQSATLMQQVHRLRA
                     VVRERLLAALPGGEQSGLLVALAVGDQQGIDTAQWEIFRRTGVAHLVSISGLHVGLVA
                     MFCGGLAAMAWRRLPALVLRMPVQRAGALAGLAGATAYALLAGMGVPVLRAWLMLLVG
                     ALALFVGRHIAPSRVLAVALLVVLAVDPWAVLSAGFWLSFGAVAVILAVLGGRVAPAA
                     GWRGALRVQFAISFALVPLLLAQFQSVPLLSPLANLIAIPLVSFVVTPLVLLAIPWPT
                     PLLLVPADLAAGWMMAFLAPLAALEMAVVERALPPPWLFGCALVAVAMLLLPRASPGR
                     LVAPALLAGLLFWQPPRPQEGGFRAWVLDVGQGLAVHVQTRAHDLLYDSGPPFGSSTD
                     AGERVILPWLRAAGVRRLDRLVLSHPDADHAGGAASLLGSIPVERVLAGQARDARERA
                     DWSERLGQGREPADCALAPAWQSDGVRFEVLHPAPEGPPRDQASGAHDNDASCVLRIS
                     AAAGALLLTGDIGTIAEAKLIARQAPASLAAAVVVSAHHGSRSSSSTAFVDATLPEHV
                     IHSVGRRNSFGHPHPEVWARWADAGARNWRTDAQGAIVIEFAAAPGDGVQVSAVRETR
                     PRYWHGR"
     gene            12578..13564
                     /locus_tag="P5537_09275"
     CDS             12578..13564
                     /locus_tag="P5537_09275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HRV78271.1"
                     /translation="MSLLDSLKKLFRPSAAESAADRNTTQGGQTLAVGHEPTIGSALQ
                     PRARRVLCSGPHGLHNMAYTEWGDAKNPRVLVCVHGLTRNGRDFDDLARALAGEYRVV
                     CPDVVGRGRSDWLADKADYGFPVYVADMVTLIARADVEEVHWVGTSMGGIIGMLLASQ
                     PATPITRMVLNDVGPVITAASLRRIGQYVGRAPRFADLAAAEAYIREVGAPFGALADA
                     QWRHLTEYSVRRMDDAEGGYAMIYDPGLGEVFRLNPVPVDIDLWPVYEAIRCPTLALR
                     GAESDLLEASTLAAMGTRGPQARTVEFSGVGHAPMLMDAAQIAVVRDFLLGT"
     gene            complement(13668..14612)
                     /gene="rsgA"
                     /locus_tag="P5537_09280"
     CDS             complement(13668..14612)
                     /gene="rsgA"
                     /locus_tag="P5537_09280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HRV78272.1"
                     /translation="MRKRTHAGTISEGRIDGLVVAAFGRHYEVDTARGRLQCYPRGKK
                     SSYACGDEVELVPGGDGQGVIEALHPRRNLLWRSDAFREKLIASNLSHLVIVVATEPG
                     FSDLLVSRCIAAAESQGIVPLIVLNKADLAERLEAARSQLEPFRKLGYEVVEVSALQG
                     ADALRARLAGLQAIFVGQSGMGKSTLTNAIVPEARAATREISDALDSGKHTTTFARLY
                     RLPLETDEAGGGWLIDSPGLQVFGLAHLAADDLAETFVELRPHLGRCRFRDCRHDSEP
                     GCALLGALAAGAIHPRRWEHFRAIRSEIAEARRLNPGW"
     gene            complement(14618..15904)
                     /locus_tag="P5537_09285"
     CDS             complement(14618..15904)
                     /locus_tag="P5537_09285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HRV78273.1"
                     /translation="MTDSALFQLSPLALQPFSLVFLAFLLAGTMLGLGLLHRHAHHVR
                     RHRDAVPQPFADSIPLHSHQRAADYTFARARLSAIHAVANAGFVLLLTLGGGLQAVHD
                     AWAGVLPAGGLGHGVALLASLGVLGWLFELPFALLRTFGIEKAFGFNRMTPRLYLADT
                     LREAALAALIGLPLLGGVLWLTLAMGELWWAWVWAFWLGFNLLAMVIWPTFIAPLFNK
                     FTPLADAALKARVEALLARCGFRAKGLFVMDGSRRSAHGNAYFTGLGAAKRIVFFDTL
                     LDKLDADEVEAVLAHELGHFHHHHLVRRLAVLAPASLGVLALLGWLAQQPWFFSGLGM
                     QGSDMASALALFTLVLPVFSFPLAPVLSHWSRKNEFEADAYAARQADAGKLVSALVKL
                     YRDNASTLTPDPLYSRFHDSHPPAALRIARLQALQR"
     gene            16098..16646
                     /gene="orn"
                     /locus_tag="P5537_09290"
     CDS             16098..16646
                     /gene="orn"
                     /locus_tag="P5537_09290"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011765251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000175 - 3'-5'-exoribonuclease activity
                     [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoribonuclease"
                     /protein_id="HRV78274.1"
                     /translation="MAQDPKTLIWLDMEMTGLEPDRDRIIEIAIVLTDEALEVIAEAP
                     VIAVHQPDSVLDGMDDWNRNTHGKSGLSARVRASTVSEAEAEAQVLAFLREHVPARTS
                     PMCGNSVCQDRRFLARWMPELEAWFHYRNLDVSTLKELARRWRPEIYAGVKKAGSHTA
                     LADIHESIAELRHYRDHFLRLA"
     gene            16672..16833
                     /locus_tag="P5537_09295"
     CDS             16672..16833
                     /locus_tag="P5537_09295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78275.1"
                     /translation="MRIDPAALLRSLLAWARRHRRVLIVLALLSLFFSVLGYFTNPVS
                     LPGMCKIYG"
     gene            complement(16853..18511)
                     /locus_tag="P5537_09300"
     CDS             complement(16853..18511)
                     /locus_tag="P5537_09300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78276.1"
                     /translation="MFRDPATPTLFQRRVYGTIGLTLLVGLYLLVGLTSHDPWRGDDA
                     RHFGPVLAMLRGESWLFPLLAGEPLVEHPPLYYWVASAFSALTAAFLPAHAGARLASA
                     FFVALAIWWLARAAEALHGRSARTPAALLGLGTLGLVLHAHETQPLLALFAMLALTLS
                     GLAELPGRPLAGGLKAGVGSGLAFLAAGFGGLWMSAPLLPLAMLLSADCRSPRASGAL
                     LLGLCAAMTIAALWPLALHLQQPELLGLWLRNEWQWLGGPALRAAELPRLLELGAWFM
                     WPLWPLALWALWRGRRQAGGLAILLPLASGVLALAWLLAIDDLSQARLIPLVPALALL
                     AAGGVASLRRGAASALDWFSLMSLAVFGLLVWLAWSAQVVGWPTGLARHVARNAPDFV
                     PPDADLRLFAGVAISALWILLVARLPRSPARAPANWTIGLVMLWSLAVVLLMPWFDHG
                     RSYRAVVESLEIAVRGERGAQAKECIATTGLPDAMRLSMDYFAGLRARAIDADATPCA
                     LLLVHVERRGQAAALAPEWETVWEYRRGAGKRAETFRLLRRAGG"
     gene            complement(18690..18908)
                     /gene="rpmE"
                     /locus_tag="P5537_09305"
     CDS             complement(18690..18908)
                     /gene="rpmE"
                     /locus_tag="P5537_09305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HRV78277.1"
                     /translation="MKADIHPKYADVNVTCSCGNTFVTRSTMGKPQYHVEVCSACHPF
                     YTGKQKIVDTAGRVERFRQKYGNVQRAS"
     gene            19089..20111
                     /locus_tag="P5537_09310"
     CDS             19089..20111
                     /locus_tag="P5537_09310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HRV78278.1"
                     /translation="MRLLLAPMEGVADFVLRDVLTAIGGYDLAVSEFVRVSGTLLPRR
                     MFERICPEILTGGRTAAGTPVAVQLLGSDPDLLAGNAARLAALSPHGIDLNFGCPAKV
                     VNRHGGGAMLLDRPRLLHDIAAAVRAAVPADVPVTAKMRLGIADPSQAIDCAQALAEG
                     GAQAIVVHARTRDQGYRAPAHWEWVARIGDAVRVPVTANGEVWGVPDWARCRAVSAAE
                     DVMIGRGAVSDPWLARRIRGERAPEPDEHDWVELHPHILRYWEGVQGRAAPVHACGRL
                     KLWLGMLRRHYPAAGRLHEAVRRVVHPARMNEELRRHGIPARDHLPATAVDAPRQTCT
                     TTCPDR"
     gene            20122..20799
                     /locus_tag="P5537_09315"
     CDS             20122..20799
                     /locus_tag="P5537_09315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HRV78279.1"
                     /translation="MSYANSRIPQSAQQGVHEALAERVRKHLEHPFRKPCTDYNRAAL
                     AEALADWDRSAPLILDAGCGVGHSTIQIARQFPDHWVIGVDQSADRLARRKPYPEALL
                     PKNMVFVRADLVDFWRLLDEAGLRLARHYLLYPNPWPKIGHLGRRWHAHPVFPWIPRL
                     GGVLECRSNWKVYIEEFACALGLVLGREVAWECFEAATPLTPFERKYRDSGQPLYRIG
                     LDLAAAG"
     gene            20878..>21611
                     /locus_tag="P5537_09320"
     CDS             20878..>21611
                     /locus_tag="P5537_09320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0149 family protein"
                     /protein_id="HRV78280.1"
                     /translation="MEEKGADASALRTMSDEDFEALEEILTSDIVPEDCMDLEMLDGY
                     LAGVMISPRPIAPERWMPGVWSAHGDEVGFGSGSGLQRAIRLVKAYHNELLATLGLDD
                     EDEACWEPFCFAVAEGDGLKLGEAWVDGFAQGLDLWPEGWEEGLDAEAVEAVRETLDE
                     VLAPWGEEDAAKADDETRLGWLADVGEAVNDIFAHWRDLGLPAAEPLSTEAPRKPASA
                     TPGRNDPCPCGSGKKYKKCCGANGAEA"
BASE COUNT         3163 a         7518 c         7750 g         3080 t
ORIGIN      
        1 gatgccgcac ccgcccgcct cgcccgatac aatagcgccc atcatgcgct cacaccctgc
       61 ctccaacgcc ctggtttccg ttggcgaatc aacggtttcc agcatcctct ccgcggccgc
      121 ccgcagccgc cgcgccgccc ccttcctgcc catgtcgcgc gccgagatgg acgtgctcgg
      181 ctgggaccag tgcgacgtca tcctggtgac cggcgacgcc tacatcgacc atcccagctt
      241 cggcatggcg ctcgtcggac gcctgctcga ggcgcacggc tttcgggtcg gcatcctcag
      301 ccagcccgac tggcactctg ccgagccctt ccgtgcgctg ggcaggccgc ggctgtactt
      361 cggcatcacc gcgggcaaca tggactcgct ggtcaaccgc tacacgtccg accgcaagat
      421 ccgctccgac gacgcctaca cgcccaacgc cgaggccggc aagcgccccg accgcgcggt
      481 gaccgtgtac gcccagcgcg cgcgcgaggc ctatccgggc acgccgatcg tcatcggcag
      541 catcgaggca agcctgcgcc gcatcgccca ctacgactac tggtctgaca aggtgcggcg
      601 ctcggtgctg cccgactcca aggccgacat cctgctcttc ggcaacgccg agcgcgcgct
      661 ggtggcgctg acccatcggc tcgacgcagg cgagccgatc gagtccattc gtgacttgcg
      721 cggtaccgcc ttcatggtca agccgggctg gaagccggcc gcggactggc acgagctcga
      781 ctcgcgcgcg ctcgacaagc ccggccgcat cgacgcccat ccggacccct acgccatgga
      841 accgacggcc gctgcgccca agtccgcggc cgacggcgcc cagccggtgc gcatcgtgcc
      901 cgcggccgag cgcctggcgg cgcgccgcgc cgaccgtgca cgcacggtaa tccgcctgcc
      961 gtcctacgag gaggtcaagg acgacccggt gatgtatgcc cacgcctcgc gcgtgttcca
     1021 cctcgaatcc aaccctggca acgcacgcgc actggtgcag tgccacggcg aggggccagg
     1081 cgcgcgcgac gtgtggatca acccgccgcc ggtgccgctg accacgcccg agatggactt
     1141 cgtctacgac cggcccttcg cgcgtgcgcc gcacccgatc tacggcggcg cgcgcatccc
     1201 ggcgtgggac atgatcaagt tctcgatcaa catcatgcgc ggctgcttcg gcggctgcac
     1261 cttctgctcg atcaccgagc acgagggccg catcatccag agccgttcgc acgaatcgat
     1321 cattcacgag atcgaggaga tccgcgacaa gtcgcccgac ttcaagggcc acatcaccga
     1381 cctcggcgga cccaccgcca acatgtaccg catggcgtgc aagagcaagg cgatcgagga
     1441 gaactgccgg cggctgtcgt gcgtgtatcc ggggatctgc gagaacctga acaccgacca
     1501 ctcctcgctg gtcgagctct accgcaaggc gcgcgcggtg ccgggcatca agcgcatcac
     1561 catcggctcg ggcctgcgct acgacctcgc ggtgcgctcg ccggagtacg tgaaggaact
     1621 cgtcacccac cacgtcagcg gcctgctcaa gatcgcgccc gagcacaccg aggagaacac
     1681 gctctcgaag atgatgaagc cgggcatcgg cgcgtatgag gaattccgcc agatgttcga
     1741 gaagttttcg gcgcaggcgg gcaagaagca gcacctggtg ccgtacttca tcgccgcgca
     1801 cccgggcacg accgacgagg acatgctcaa cctggcgctg tggctgaaga agaacaactt
     1861 ccgcctcgac caggtgcaga ccttcctgcc cacgccgatg gcgctggcga ccacgatgta
     1921 ccactcgcgc aagaacccgc tgaagaaggt ctcggcggat tccgaggtgg tcgagaccgc
     1981 gcgcgccggc cgcatccgca agctgcacaa ggccttcctg cgctggcacg acccggagaa
     2041 ctggccgctg ctgcgcgagg cgctgatcga gatggggcgc gccgagctga tcggcaacgg
     2101 cccgcactgc ctggtgccgc gccagcagcc ggcacagctc gtggccgcgc aggcaggggg
     2161 ggcgcgcgag ggcgccgggc gtcctgcgtc caaaggccgc gaggccggtc gcgcgcccgg
     2221 agcggcgggt cgcaagggcg acgcgggcgg gcgcgggagc gcagcccgcg gctcaccagg
     2281 cggggcgggc gagcgcaagc cgggtggctg cgccaagccg cgcagccggc gcggcgctta
     2341 ggaggcctgc tgcgtctcga gccggttgcg cccgccggcc ttggcgcggt acatcgcctc
     2401 gtcggcccgt cgcagcaggt cttcggcgcg ctcttcgcca ccgtcgaagc aggcgatgcc
     2461 gatgctgggc gtgctgcggt gtcgtaccgt cccgaggtcg tagggtgcgt tcaagtcggt
     2521 gaggatcttg tcggcgatca gcgtcgcctt gtccgccgcc tcgggcgcgg cctcgccgag
     2581 atcctccagc atcaccacga actcgtcgcc gccaaggcgc gccacggtgt cgccttcgcg
     2641 caccgccttg cgcaggcgcg ccgcgatctc gcatagcagc tggtcgcccg cctcgtgacc
     2701 gtaggtgtcg ttcacccgct tgaagtggtc gatgtcgatg aagagcaggg cgccgtggcg
     2761 gccatggcgt cgggcgttgg ccaggccctg gcgcaggcgg tcgagcagga agcggcggtt
     2821 gggcagctgg gtcagcgtgt cgacgaaggc gaggttgcgg atcgcctctt cggcggtctt
     2881 gcgctcggtg acgtcgatga tcacgccatc gagccgcaga ggcttgtcgt ccacgtcgac
     2941 cgccacccga ccgcgctcgc tgacccaacg gatccgtccg tcgcgtccgc gcatgcggta
     3001 ttccacctcg tagttggcat ggcaggcaca tgcgttctcg atcgcggcga cgatcgccgg
     3061 tacgtcttcc tgcaggatga agtcgccgaa cgtgacccgg cccgacatga actcgtcggg
     3121 cgtcgcgccg gtgagcaggg tgatcccgcg gctgatgtgc atcaccttcc atggcacctc
     3181 gatctggcag cggaagacga cgccgggcac gttctcgacc agggtgcgga actcgtcccg
     3241 gctgcgtgcg agatgaaggg ctgcggcgtg catgcggcgg cggtggcggg cgttgctgtg
     3301 catcaccgcg aacaacatga cgctgagcgc gctgccgccg tagaggatga gcgccggctc
     3361 ggcgctcgcg tggtcggcct cgaaggcggg cgtgctgccg aagctcgcga tccatttgcg
     3421 gccggcgacc tccacctcgt ggctggcgac gtagcgtgcc gtccggtcgt gccctgccga
     3481 tgcgtagagc agcgtctgca atgactcgtg cagatcgtgg agctcgatgt gggcatcgcg
     3541 caggtcgtcg cggaagatgg cctgcatcat gtcgagggcg cggaacgggg cataaacgaa
     3601 gccgagcagg gccgcacggc gttcctcgac cgtggcgagc ggtctgtcct tcgcatacac
     3661 gggcagatac atcaggaagc cgggctggac ctcggtgccg aactcctgga ccaggatcac
     3721 cctgccgctg agggcggcgc gtcccgtgtc gcgcgcgcgc tccatggcct cgcgccgcac
     3781 cggttcggag tacatgtcgt agccgaaggc gcgtcggttg cgcgcatcga agggttcgag
     3841 aaagacgatg ctgctgtatt gggcgcgaga cccgggcgga tgcacgtcat agtccggaaa
     3901 gccttggctg cggacctccg cgacgtgggc ggccagcgcg gacgccggga acatggcggt
     3961 gaagccggtg ccctgtatac cgggcagcga gcgttcgagg tggagggccg cgacatactc
     4021 gccccattcg gcgcggctga ccgcgtcgct cgccgcgaac agcgcggcgc cgccgtgcag
     4081 cacctgttcg taggcctgca tgcgcgagag caggttgtcg cgggcgagcg cggcgtggtt
     4141 ggcgaagcga tcgcgcgtcc ggtcctcgag atgctcgccg acgtatcgcc acagcaccag
     4201 cgtcagcagc accccgaaca cgagcgcgag ccaggcggcg gtgctgcgat cgagcatgcc
     4261 gccagtgcga acctgtggag agccggcgtc ctgcgtcatg agcggatgat gtgcgactgg
     4321 aaggcttgcg cacgagtgtt ccacgaatcg cgcggggctg ccagcccgcg cgcgccgccg
     4381 aacccgcgac agggcttaca tccgcatgcg tttcgaggtc gcgcgcgcgg ccgccagcgg
     4441 gcacaatgcc ggccttgtcc ttccggccac cggcaaccgc aagcaatgcc atacgaactc
     4501 ctcgtcggcc tgcgctacac ccgctcgcgc aagcgcgccc aggggcgcaa ccgcttcatc
     4561 tccttcatct ccctggtgtc gatgttcggc atcgcgctcg gtgtcgcggc gctgatcgtc
     4621 gtgctgtcgg tgatgaacgg cttccaggaa gagctgcgca cccgcatcct cggcgtcgcc
     4681 tcgcacgtgc aggtgcagag cccggagggt gggctcatgg cctggcagca ggtcgccgac
     4741 gaatcccttc gccacccggc ggtacgcgcc gcagcgccct acgtgcagga gcagggcatg
     4801 ctctccttcg acgagggcgt gcgcggcacg ctcgtgcggg gggtgatccc gtccgcggag
     4861 gacaaggtcg ccgacttcgg ccgctacatg caggcgggca gcttcgatgc gctgcaggcc
     4921 gggcgcttcg gcatcgtgct cgggcgcgac ctcgccgccg cgctgcgcgt gcggctcggc
     4981 gagaaggtca ccctgatcgc gccgcagggc ctggtgaccc cggcggcggt gctgccgcgg
     5041 gtcaagcagt tcgaggtggt ggggatcttc gaggccggca tgtacgagta cgactccagc
     5101 ctcgcgctgg ttcacatcgc cgacgcccag gcgctgtacc ggctgggcga cgcggtgagc
     5161 ggcgtgcgct tgaagctcga cgacctcttc gccgcgccgc gggtggcgcg cgaactcgcg
     5221 atgacgatca gcgagccggg cctcgtcgtt gccgactgga cgcgcagcca cgccaacttc
     5281 ttccgcgcgg tggcgctcga gaagaccatg atgacgctga tcctcttcct gatcgtcgcg
     5341 gtcgcggcct tcaacatcgt gtccacgctc gtgatggcgg tgcaggagaa gtacgccgac
     5401 atcgccatcc tgcgcacgct gggcgcgagc ccggcctcga tcatggcgat cttcgtgctg
     5461 cagggctcgg tgatcggcct ggtcggcctg gccgccggtg tcgcgggcgg gctggcgatc
     5521 gcgcacaacc tcgacgtggt gatcccggcg ctggagacgc tcaccggcgc cacgctgtgg
     5581 aacaaggaga tctactacat caacgagctg ccttcgcagg tcctgtggtc ggacgtcagc
     5641 accatcgtca ccgtgtcctt cgtgctgacc ctgatcgccg cgctctaccc gagctggcgc
     5701 gcctcgaagg tcaatcccgc ggaggcgctg cgctatgagt gaaatcccga acagcggcgc
     5761 ccagcccgcg gtggtcgcat gcaccggcct gtcgaagcac ttccgcgagg gcgcggaggc
     5821 ggtgcgcgtg ctcgacggcg tcgagctcga ggtgcggcgc ggcgagcgcg tcgcgatcgt
     5881 cggctcgtcc ggctcgggca agagcacgct gatgcacctg ctcggcgggc tggacgtgcc
     5941 cagcgccggc agcgtgcggc tgatggggca ggacttctcg accatgtcgg aggccgcgcg
     6001 cggccggctg cgcaacgccg cgctcggctt cgtgtaccag ttccaccacc tgctgccgga
     6061 gttctcggcg ctcgagaacg tcgcgatgcc gctctacatc cgccgcgtcg cgcgcgccga
     6121 ggcggacgag cgcgccgcgc agatgctgcg cgaggtcggc ctcggccacc gcctcgacca
     6181 cgccccgggc gagctctccg gcggcgagcg ccagcgtgcc gcaatcgcgc gtgcgctcgt
     6241 cacccagccc gcctgcgtgc ttgccgacga gcccaccggc aacctcgacc gccgcaccgc
     6301 cggggcagtg ttcgacctca tgctctcgct caatgagcgc ctggcgacca gcttcgtgat
     6361 cgtgactcac gacgagaccc tggccgcgcg tgcgcagcgc accttgcgcc tggtggacgg
     6421 acggctgggc ggctgagaaa ggaaatttcc cggcggcggc ccgggatggg tcaagttctg
     6481 ccggaaacga ccgtatacag gctcgaagac catcctgtcc ggcctccgcg ccgggaatcg
     6541 agccatgaaa attctcttcc agcctgctgt ccgcctgctc gatcgcctga gttatccgct
     6601 caagttcggg ctcatcatcc tcgtctgcgc cgtcgcctcg gtgatcctgc tcgtgcagat
     6661 cttcaccagc ctgcgcgacg agatccgcgt caccgaacgc gagatcgccg gcctgcatct
     6721 gttcgatgcc ggcttcggcg tgatcctcaa gacccagcag caccgcggcc tgtccgccgg
     6781 ggtgctgggc ggcagcagcg agctggcgcc caagcgcgag gcgaaggcgg ccgagctgcg
     6841 tgccgcgatc ggcgcgctcg acgcagccat cgacggcgat gcgggctggt ctgggctgcg
     6901 cgcaggctgg caggcacagc ggggcgagct ggtgcgccta gccgacagcg gactctccat
     6961 gccgggggcg gagaacttcc gcctgcacac cgccacgatt gccggcctga tgcgctggct
     7021 cggcgagctc ggcgacgcct ccgggctgtc gctcgacccc gaagcggcga gttcgaacct
     7081 gctcgcgccg ctgctcggag cgctgccgga gctcagcgag cgtctcggtc agttgcgcgc
     7141 ccgcggcacg gcgctgagcg cccgccgcga gctctcgcgt agcgacgagc acgccctggt
     7201 cgcgttgctc gccgagatcg gccgcgccga atccgccgtg ctggagcgcc tgcgccgcac
     7261 cgcggcggcc aatgccagcc tcgccggcag tgtcgacggc atgggccgcg agatctccga
     7321 gggggtcgcg cgggtgcgcg aggccacccg ccaggagctc ctcgaccagc gcttcggcct
     7381 gagctcgacg gccttcttcg atctcgtgac gggcgcgatc gacactgcgg tgcgcaactt
     7441 cgaccaggtg ctgcgtccgg aggtcggccg cctgctcgcg gcgcgcctcg accgcctgaa
     7501 ccagcgcctg aacacccagg tggcgatctc ggtgctcggg atgctgctcg ccggctacct
     7561 cttcatcggc atctacctcg ccatcgtgcg ctcggttcgt gagctctccg ctggcgcaca
     7621 gggctttgcc gcgggcgact atcgcagccg ggtggacttt tccgctcgcg acgagctcgc
     7681 cgaggtcgca cgccagttca actcgatggc cgatcacgtc gccggcctga tccgcgacat
     7741 ccagaccggc gccgcccacg tcggcagcgc cgccaccgag atgtcggcct cggcgcgtcg
     7801 cgtgctgcag ggctccgaga cccagagcga cgccgcctcc agcgtcgccg cagcggtcga
     7861 ggagatgacg cgcggcgtcg acggcatcgc ccaccacgcc tcgaccgcgc agcagctcgc
     7921 cgaggactcc ggccgcctgt cgcaggaggg gcgctcggtc atggagcagt cggtggccga
     7981 gatggagcgc atcgccgagg cggtcgacct gtccagcgag gcgatccgcg agctcggcga
     8041 gaagtcgcgc cagatcaacg cgatcgtcga ttcgatccgc gacatcgccg accagaccaa
     8101 cctgctcgcg ctcaacgccg cgatcgaggc ggcgcgcgcg ggcgagaccg ggcgaggctt
     8161 cgctgtggtg gccgacgagg tgcgcaagct cgccgagcgc acctcgctcg ccacgcgcga
     8221 gatcggcggc atggtggcgg cgatccagca gggcaccgag cgcgcggtcg acaccatgca
     8281 gcagggcgtg cagcgcgtgc gcgacggcgt cgagatgagc aaccgcgccg gctcgtcgat
     8341 ggcacagatc agcgcgggcg ccgaccaggt gctcaccgcg gtgcgcgaga tctccaccgc
     8401 gctgcacgag cagagcctcg cgagcaacga catcgcgcgc aacatcgagc gcatcgccga
     8461 catgaccgaa cacaacagcg tgaccgtgcg cgagaccgcg gccaccgccg agacgctcga
     8521 gcagctctcc ggcaccctgc gcgagcaggc cagccgcttc cgcgtttgat cgccgccgcg
     8581 ccacgaagct aagggttgtc gaggagcccg gggatcggcg cgaagcttgc gccgactccc
     8641 gggctcgatc atttgcgagc gggcaaggag tcgcagcgct tgcgccgctg ccgccactgg
     8701 cggatcagcc acagccgcca gccccagcgc accgccagat acgagaccat cgacaggctc
     8761 gccgcgagca cgatcaggcc gaccaccagc gggcgaccca gctcgcccgc ccaggcggcc
     8821 aggtcggtgg cccaacgcgc aggatcgaag cccgcgaatt cgggcggagg gacgaagtcg
     8881 acctcgccgt cccccgagat ctggctgccg atcgcgaagg ccgcgacgta gagcggcacg
     8941 atggtgagcg ggttgctgta cagcgtggtg acgagtgcca gcggcaggtt gacccgcaac
     9001 agcacgcaca ggagcgccgc gcccggcatc tggaaggggc cggggatcag gccgcagaac
     9061 atccccaccg ccaccgcccc ggccgccgag tgacggttga ggtgccacag ccgcgggtgc
     9121 agcagggtgg acgcgaaggg ccgcagccag cggttctcgc tgacgctgcg gtgatcggga
     9181 aggaagcgtt tgaagagctt gcgcatggcg tcggtccggg tgcgcgagtc tagcaaacat
     9241 ggggagcgcg ggagcgacgt cagtgcggat gccgagcgcc gccttcgcgc ctgccggcgc
     9301 tcctacagaa gccgccgcgc gtcccgggcg tcctgtagga gctgcggcag ctgcgaaccc
     9361 ggcggtccgg tgatcgacgc gcgtacagaa ctccaccgcc gccttcgcgc ctgccggcgc
     9421 tcctnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnngtgatc gacgcgcgta
     9541 cagaactcca ccgccgcctt cgcgcctgcc ggcgctccta cagaagccgc cgcgcgtccc
     9601 gggcgtcctg taggagctgc ggcagctgcg aacccggcgg tccggtgatc gacgcgcgta
     9661 cagaactcca ccgccgcctt cgcgcctgcc ggcgctcctg cataaaccgt tccgcgtctg
     9721 gaggcgcgtg taggagcggc ggcagccgcg aatggggcgg tgccgacatc gggatgtggg
     9781 tgcgggcctt gcttggcgtc caaccgctgg cggcgttgcg ccaggtggtt cgggtggaac
     9841 cggtcggtga aagaacgcgc tcccgggaat gtctgagaca taatgaatgc catgcgcatc
     9901 attgctctcg gctttcttgc aggcacgctc ctcgtccaga atgcggacac gctcgacggc
     9961 ctcacggtcg cgggcgggct aggggtgggc gcggcggtgg gcttgcggct ggccttggcg
    10021 cagggcctcc tcagggttca agcgacccga cgccgggttg gtatcgccct caccgccttc
    10081 gccgcgctcg ccgcaggcgt ggcctggaca gcgtggcggg ccgaggtccg cctgggtgac
    10141 gagctcgccg gtgcgctcga gggcgtcgag ctgcggctgc ggggcagggt ggccgggttg
    10201 ccacgggcga gcgggccggg ctggcgcttc gacttcgagg tcgagcccga cacgccgggc
    10261 gtacccggcc tcgtgcagct cggctggcga cccgagggag gcgatgccga caccaacgcc
    10321 gactccgtgg cgccgcggat gctgccaatg ccccgcccgg gcgagcgctg ggcgctcacc
    10381 gtgcgcctgt ggcggccaca cggcttcgcc aatcctgcga gcttcgacta cgaggcctgg
    10441 ctcctcgagc gtggagtgcg tgccaccggc agcgtgcgcg gaccgggccg tctcctcgac
    10501 gagcagtccg ccaccctcat gcagcaggtc caccgcctgc gcgcagtggt gcgggagcgc
    10561 ctgcttgcag ccctgcccgg gggggagcag tccggcctgc tggtggcact cgcagtcggc
    10621 gaccagcaag gcatcgacac cgcccagtgg gagatcttcc gccgcaccgg cgtcgcccac
    10681 ctggtgtcga tctcgggcct ccatgtcggg ctcgttgcca tgttctgcgg cgggctcgct
    10741 gcgatggcct ggcgccggct gccggccctg gtgctgcgta tgccggttca gcgcgcgggg
    10801 gcgctggcgg ggctggccgg ggcgaccgcc tatgcgctcc tcgccggcat gggggtgccg
    10861 gtgctgcgcg cgtggctgat gctgctggtg ggtgcgctcg cgctgttcgt cgggcgccac
    10921 atcgcgcctt cgcgggtgct cgcggtggcg ctgctggtgg tgctcgcggt ggacccgtgg
    10981 gcggttctgt ccgccggttt ctggctctcc ttcggcgcgg tggcggtgat cctcgccgtg
    11041 ctcggcgggc gggtggcgcc agcggccggc tggcgcggcg cgctgcgggt gcagttcgcg
    11101 atcagcttcg cgctggtgcc gctgctgctc gcgcagttcc agtcggtccc gctgctgtcg
    11161 ccgctcgcca acctgatcgc gatcccgctg gtgagcttcg tcgtcacgcc gctggtgctg
    11221 ctcgcgattc cctggccgac ccccttgctg ctggtgccgg ccgaccttgc cgcgggctgg
    11281 atgatggcgt tccttgcacc cctcgcagcg ctcgagatgg cggtggtcga gcgtgcgcta
    11341 ccgccgccct ggctgttcgg ctgcgcactc gtggcggtgg cgatgctgct gctgccacgc
    11401 gcaagcccgg gtcggctggt ggcgccggcc ctgctggccg ggctgctgtt ctggcagccg
    11461 ccacgtccgc aggagggtgg ctttcgcgcc tgggtgctgg atgtcgggca gggcctggcg
    11521 gtgcatgtac agacgcgcgc acacgacctc ctgtacgaca gcggcccccc cttcggcagt
    11581 tcgaccgatg ccggcgagcg cgtgatcctg ccgtggttgc gcgcggccgg cgtgcgccgg
    11641 ctggaccggc tggtgctgtc gcatccggac gcggaccatg ccggcggtgc ggcctcgctg
    11701 ctcggttcga ttcccgtgga gcgggtgctg gctggacagg ctcgcgatgc gcgcgagcgt
    11761 gcggactggt cggaacggct cggccaggga cgcgagcctg cagactgtgc gcttgcgccg
    11821 gcgtggcaaa gcgacggcgt gcgcttcgag gtactgcatc ctgcgccgga gggcccgcca
    11881 cgcgatcagg cctccggcgc ccacgacaac gacgcttcgt gcgtgttgcg catctccgct
    11941 gcggcgggtg cgctgctgct gaccggcgat atcggcacga tcgccgaggc gaagttgatc
    12001 gcgcgccagg cgccggcaag ccttgctgcc gcggtcgtgg tcagcgccca tcacggcagc
    12061 cgttcctcgt cctccacagc cttcgtggat gcgacgctgc cggaacacgt gatccactcg
    12121 gtcggtcggc gcaacagctt cggccatccg caccccgagg tgtgggcacg ctgggccgat
    12181 gccggtgctc gcaactggcg caccgatgcg cagggcgcga tcgtgatcga gttcgctgct
    12241 gcgcccgggg atggcgtaca ggtgagcgcc gtgcgcgaga cgcggccgcg ctactggcac
    12301 ggccgctgag gccggagagg aatgggtgac ggcaggcaaa agggcgtcga ggagccgacg
    12361 cgcgtgccgg ttccgggcgc cgccttcgcg cctgccggcg ctcctacagg aggcggggcg
    12421 gcttcgattt tcttgttgag gagcggcggc aggcgcgaag acggcggtgc gcaacgcgat
    12481 gcgtgcacgg ccggatcatc ctgttcatgc gtcccggccg cctcgcttcg ggctagactt
    12541 gcagtcaccc gaagcccgat cggagtaccc gcgcctcatg tccctgctcg actcgctcaa
    12601 gaagctcttc cgcccgtccg cggcggagtc cgccgccgac cgcaatacga cgcagggggg
    12661 gcaaacgctt gccgtggggc atgaacccac catcggcagc gcgctccagc cgcgcgcgcg
    12721 gcgggtgctg tgcagcgggc cgcatggtct gcacaacatg gcctatacgg aatggggcga
    12781 cgcgaagaac ccgcgcgtgc tggtctgcgt gcacggcctc acccgcaacg gccgcgactt
    12841 cgatgacctc gcgcgggcgc tcgccggcga ataccgggtg gtgtgcccgg acgtcgtcgg
    12901 gcgcgggcgc agcgactggc tggcggacaa ggcggactat ggtttcccgg tgtacgtggc
    12961 ggacatggtc acgctgatcg cgcgtgccga cgtcgaggag gtgcattggg tgggcacctc
    13021 gatgggcggc atcatcggca tgctgctcgc gagccagccc gccacgccga tcacgcgcat
    13081 ggtgttgaac gatgtcggac cggtgatcac cgccgcctcg ctgcgccgta tcggccagta
    13141 tgtcgggcgc gcgccgcgct tcgccgacct ggcggcggcg gaagcctaca tccgcgaagt
    13201 gggcgcgccc ttcggcgcgc tcgccgacgc gcagtggcga cacctcaccg aatattcggt
    13261 gcgccgcatg gacgacgccg agggcggcta cgcgatgatc tacgaccccg gcctgggcga
    13321 ggtcttccgg ctcaacccgg tcccggtcga tatcgacctg tggccggtgt acgaggcgat
    13381 ccgctgcccg acgctggcgc tgcgcggggc cgagtccgac ctgctcgagg cgagcacgct
    13441 ggcggcgatg ggcacgcgcg ggccgcaggc gcggacggtg gagttttccg gggtcggcca
    13501 cgcgccgatg ctgatggatg cggcgcagat cgccgtggtg cgcgacttcc tgctcggcac
    13561 ctgagcacgc ggcgccaggc tgcggcgggg tgtgcacgat gggcggtcgc ggcaggtgac
    13621 gctcccgatc gtcgtcccgc tcgggcaagg cgcccgcgca cggcggtcta ccagcccggg
    13681 ttcagccgcc gcgcctcggc gatctcgctg cggatggcgc ggaaatgctc ccagcgccgc
    13741 gggtggatgg cgccggccgc gagcgcgccg agcagcgcgc agcccggctc gctgtcgtgg
    13801 cggcaatcgc ggaaacggca gcgccccaga tggggacgca gctcgacgaa ggtctcggcg
    13861 agatcatccg ccgcgaggtg ggcgagcccg aagacctgca ggccggggct gtcgatcagc
    13921 cagccgccgc ctgcttcatc cgtctccagc ggcaggcggt acaggcgggc gaaggtcgtg
    13981 gtgtgcttgc cggagtcgag tgcgtccgag atctcgcggg tggcggcccg ggcctcgggc
    14041 acgatggcgt tggtgagggt cgatttgccc atgcccgact ggcccacgaa gatcgcctgc
    14101 aggccggcga ggcgggcgcg cagcgcatcc gcgccctgca gcgcggacac ctcgacgacc
    14161 tcgtagccga gcttgcggaa gggctccagc tggctgcgcg cggcctcgag gcgctcggcg
    14221 aggtcggcct tgttgagcac gatcaacggc acgatgccct ggctctcggc cgccgcgatg
    14281 cagcgcgaca ccagcaggtc ggagaagccc ggctcggtgg cgaccacgat caccagatgg
    14341 ctgaggttgg aggcgatcag cttctcgcgg aaggcgtccg accgccacag caggttgcgc
    14401 cgcgggtgca gggcctcgat gacgccctgg ccgtcgccgc cgggcacgag ttcgacctcg
    14461 tcgccgcagg cgtagctgct cttcttgccg cgcggatagc actgcagtcg gccgcgcgcg
    14521 gtgtcgacct cgtagtggcg accgaaggcg gccacgacca ggccgtcgat gcggccttcg
    14581 gagatggtgc cggcgtgggt gcgcttgcgc atgcggctca ccgctgcagc gcctgcaggc
    14641 gcgcgatgcg cagcgcggcg ggcggatgcg agtcgtggaa gcgcgagtac agcggatcgg
    14701 gcgtcagcgt ggacgcgttg tcgcggtaga gcttgaccag cgcgctcacc agcttgccag
    14761 cgtcggcctg gcgggcggcg taggcgtcgg cctcgaactc gttcttgcgc gaccagtggc
    14821 tcagcaccgg cgcgagcggg aagctgaaca ccggcagcac cagcgtgaag agggcgagcg
    14881 cgctcgccat gtcgctgccc tgcatgccca gcccggagaa gaaccagggc tgctgcgcga
    14941 gccagccgag gagcgcgagc acgcccaggc tggccggagc gagcaccgcc aggcggcgca
    15001 ccaggtggtg atgatggaag tggccgagtt cgtgggcgag caccgcctcg acctcgtcgg
    15061 cgtcgagctt gtcgagcagg gtgtcgaaga acacgatgcg cttggcggcg cccaggccgg
    15121 tgaagtaggc gttgccgtgc gccgagcggc gcgagccgtc catcacgaac aggcccttgg
    15181 cgcggaagcc gcagcgtgcg agcagggcct cgacgcgcgc cttcagcgca gcatcggcga
    15241 gcggggtgaa tttgttgaac agcggcgcga tgaaggtcgg ccagatcacc atcgcgagca
    15301 ggttgaagcc tagccagaaa gcccacaccc aggcccacca cagctcgccc atcgccagcg
    15361 tcagccacag caccccgccg agcagcggca ggccgatgag cgcggcaagc gcggcctcgc
    15421 gcagggtgtc ggcgaggtaa agccgcggcg tcatgcggtt gaagccgaag gccttctcga
    15481 tgccgaaggt gcgcagcagc gcgaaaggca gctcgaacag ccagccgagc acgcccaggc
    15541 tggcgagcag cgccacgccg tggccgagcc cgcctgcggg cagaacgccg gcccaggcgt
    15601 cgtgcaccgc ctgcagcccg ccgccgagcg tgagcagcag cacgaagccg gcgttggcca
    15661 cggcgtggat ggcggacagg cgcgcgcgcg cgaaggtgta gtcggccgcg cgctggtgcg
    15721 aatgcagcgg gatcgagtcg gcgaagggct gcggcacggc gtcgcgatgg cggcgcacgt
    15781 ggtgggcgtg gcggtgcagc aggccgaggc cgagcatggt gccggcgagc aggaaggcca
    15841 ggaacaccag ggagaagggc tgcaaggcga gcggcgagag ctggaagagg gcggaatcgg
    15901 tcattgcggt gcgcaggcgg tggatggaag ttgcggctcc cggcatgcac gcagcccggc
    15961 ccgcgttgcc attcgacgcc gcccgtgacg gcctgcctcg atcgcaccgc gccggaaccg
    16021 gcagcctgta cgatctgtga cacaatcgcg ccctcgattg tttcgcagga aggccccgaa
    16081 aaagggccgc aacgattatg gcacaggacc cgaagacgct gatatggctg gacatggaga
    16141 tgaccggcct cgaacccgac cgtgatcgca tcatcgagat tgcgatcgtg ctcaccgatg
    16201 aggcgctcga ggtgatcgcc gaagcgccgg tgatcgccgt ccatcagccc gacagcgtgc
    16261 tcgacggcat ggacgattgg aaccgcaaca cccacggcaa gtccgggctc agcgcccggg
    16321 tgcgcgcctc cacggtgtcc gaggccgagg ccgaggcgca ggtgctggcc tttctgcgcg
    16381 agcatgtgcc cgcgcgcacc tcgccgatgt gcggcaactc ggtgtgccag gatcgccgct
    16441 tcctggcgcg ctggatgccc gagctcgagg cctggttcca ctaccgcaac ctcgacgtgt
    16501 ccacgctcaa ggaactggca cggcgatggc gtccggagat ctacgcgggg gtgaagaagg
    16561 cgggcagcca caccgcactc gccgacatcc acgagtcgat cgccgagctg cgccactacc
    16621 gcgaccactt cctgcgcctc gcctgagcac ccgccggacg agggtcttgc catgaggatc
    16681 gatcccgcgg cgctgttgcg gagcctgctc gcctgggcgc gccgccaccg gcgcgtgctg
    16741 atcgtgctcg cgctgctgtc gctgttcttc agcgtgctgg gctatttcac caatcccgtt
    16801 tcgctgccgg ggatgtgcaa gatctacggc tgagcccggc gagggcccgc actcagccgc
    16861 cggcgcggcg cagcagccgg aaggtctcgg cgcgcttgcc tgcgccgcgg cggtattccc
    16921 aaacggtctc ccactcgggc gcgagcgcag cggcctggcc gcggcgctcg acgtgcacca
    16981 gcagcagcgc gcacggcgtg gcgtcggcgt cgatggcgcg cgcgcgcagg cccgcgaagt
    17041 aatccatcga cagcctcatc gcgtcgggca gccccgtggt ggcgatgcat tccttcgcct
    17101 gggcgccacg ctcgccgcgg accgcgatct cgagcgactc caccaccgcg cggtagctgc
    17161 ggccatggtc gaaccagggc atcagcaaca ccaccgcgag gctccacagc atcaccaggc
    17221 cgattgtcca gtttgccggg gcacgcgcgg gcgaacgcgg caggcgcgcg accagcagta
    17281 tccacagcgc gctgatcgcc acgcccgcga acaggcgcag gtcggcgtcg ggcggcacga
    17341 agtcgggagc gttgcgcgcg acgtggcgcg cgaggccggt cggccagccg acgacctggg
    17401 cgctccatgc caaccagacc agaaggccga acaccgccag gctcatcagc gagaaccagt
    17461 cgagcgcgct cgcggcaccg cggcgcaggc tggccacgcc acccgccgcg agcagggcga
    17521 gtgcgggcac cagcgggatc aggcgtgcct gcgaaaggtc gtcgatcgcc agcagccagg
    17581 ccagcgcgag cacgccgctt gcgagcggca gcaggatcgc cagtccgccc gcctgccggc
    17641 gaccgcgcca cagcgcccac agggccagcg gccacagcgg ccacatgaac caggcgccga
    17701 gctcgagcag ccgcggcagt tccgcggcgc gcagcgccgg cccgccgagc cactgccatt
    17761 cgttgcgcag ccacaggccc aggagttcgg gttgctgcag gtgcagcgcc agcggccaaa
    17821 gcgcggcgat cgtcatggcg gcgcacagac cgagcagcaa tgcgccgctg gcgcgcgggc
    17881 tgcggcagtc ggcgctgagc agcatcgcca gaggcagcag tggggcgctc atccacaggc
    17941 cgccgaaacc tgcagcgagg aaggccaggc cgctgcccac gcctgccttc aggccgccag
    18001 cgagcggccg cccgggcagc tccgcgaggc cggacagggt gagcgcgagc atggcgaaga
    18061 gggcgagcag gggctgcgtc tcgtgcgcat gcaggacgag ccccagcgtg ccgagaccga
    18121 gcagcgcggc gggcgtccgt gcgctgcggc cgtgaagcgc ctctgcagca cgcgccagcc
    18181 accagatcgc gagggccacg aagaacgcgc tcgccaggcg agccccggca tgcgcgggca
    18241 gaaaggcagc ggtgagcgcg gagaaggccg aggcgaccca gtagtagagc gggggatgct
    18301 ccaccagggg ctcgccggca agcagcggaa acagccagga ctcaccgcgc agcatcgcca
    18361 gcaccggacc gaaatggcgc gcgtcgtcgc cgcgccaggg gtcgtgcgag gtcaggccga
    18421 cgagcaggta caggccgacc agcagggtca ggccgatcgt gccgtaaacg cggcgctgga
    18481 acagggtggg cgtggcggga tcgcggaaca tgcgggcatt gtgcgtcgga gtggctgcgc
    18541 ggaccaagcg cggcggaggg gcagggcgga gcgggggagg cgtgccggcg acgggcaaca
    18601 aaaaaaggca gcttgcgctg cctttctcgg tgtctgcgga atcctgccgc gaccgcacgg
    18661 ggcggtgagg attccggcga tgcggcggat cagctcgcgc gctggacgtt gccgtacttc
    18721 tggcggaagc gctcgacgcg gccggcggtg tcgacgatct tctgcttgcc ggtgtagaac
    18781 gggtggcagg ccgagcacac ttcgacgtga tactgaggct tgcccatggt cgagcgcgtc
    18841 acgaaggtgt tgccgcacga gcaggtgacg ttgacgtcgg cgtacttggg atggatgtcc
    18901 gctttcatgg tggtttcctg aatcttgcgg gcggaggttg tgaccgccct gtgtcgtaaa
    18961 gcgcgtcatt atcagccagc cggccgatcc tgacaaggaa aaacacggcc cgagcgcctc
    19021 gtcgggcggt tttcaggcgt gggaccggta caatcgcgcc cctgatcaac caccgagggg
    19081 gacccagcgt gcgcctgctg ctcgcgccga tggagggcgt ggccgacttc gtgctgcgtg
    19141 acgtgctgac cgcgatcggt ggctacgacc tcgccgtgtc ggagtttgtc cgcgtctccg
    19201 gcaccctgct gccacggcgc atgttcgagc gcatctgccc cgagatcctc accggcggcc
    19261 gcaccgccgc gggcacgccg gtggcggtgc agctgctcgg cagcgatccg gacctgctcg
    19321 ccgggaacgc cgcacgcctg gccgcgctga gcccgcacgg catcgacctc aacttcggct
    19381 gcccagccaa ggtggtgaac cgccacggtg gcggtgcgat gctgctcgac cgcccgcgcc
    19441 tgctgcacga catcgccgcg gcggtgcgcg cggccgtgcc cgccgacgtc cccgtgacgg
    19501 cgaagatgcg tctcggcatc gccgatcctt cgcaggccat cgactgcgcg caggcgctcg
    19561 ccgaaggcgg cgcgcaggcc atcgtcgtgc atgcgcgcac ccgcgatcag ggctaccgcg
    19621 cgcccgccca ctgggagtgg gtggcacgca tcggcgatgc ggtgcgcgtg ccggtgacgg
    19681 ccaacggcga ggtttggggc gtgcctgact gggcgcgttg ccgcgcggtc tccgccgcag
    19741 aggacgtgat gatcggccgc ggcgcggtgt ccgatccgtg gctcgcgcgc cgcatccgcg
    19801 gcgagcgcgc ccccgagccc gacgagcacg actgggtcga actgcacccc cacatcctgc
    19861 gctactggga gggcgtgcag gggcgcgcgg cgccggtgca tgcctgcggc cggctcaagc
    19921 tgtggcttgg catgctgcgg cgccactacc ctgcggcggg ccggctgcac gaggccgtgc
    19981 gccgcgtggt ccaccccgcg cgcatgaacg aggagttgcg ccgccacggc atccccgccc
    20041 gcgaccacct gcccgccacc gctgtcgatg cgccccggca gacctgcacc acgacgtgtc
    20101 ccgaccgatg agaccggccc gatgagctac gccaactccc gcatcccgca gagcgcccag
    20161 cagggcgtgc acgaggcgct cgccgagcgc gtgcgcaagc acctcgagca ccccttccgc
    20221 aagccctgca ccgactacaa tcgcgctgca ctcgccgagg ccctcgccga ctgggaccgc
    20281 agcgccccgc tgatcctcga cgccggctgc ggcgtcggcc acagcaccat ccagatcgcg
    20341 cgccagtttc ccgaccactg ggtgatcggc gtcgaccagt ctgccgatcg cctcgcccgc
    20401 cgcaagccct atcccgaggc gctgctgccg aagaacatgg tcttcgtgcg tgccgacctg
    20461 gtcgacttct ggcgcctgct cgacgaggcc gggctgcgcc tggcgcgcca ctacctcctc
    20521 tatcccaacc cctggcccaa gatcggccac ctcggccggc gctggcatgc gcacccggtg
    20581 ttcccgtgga ttccgcgcct cggcggcgtg ctggaatgcc gcagcaactg gaaggtctat
    20641 atcgaggagt tcgcctgcgc gctcggcctc gtgctcgggc gcgaggtcgc gtgggaatgc
    20701 ttcgaggcgg ccacgccgct cacccccttc gagcgcaagt accgcgactc ggggcaaccg
    20761 ctctaccgca tcgggctgga tctcgcggcc gcgggctgat tccgcaagat cgtgcttgcc
    20821 cgccgcgccg ccttgggcca cccttggcgc cggtcacagg agattgccat gaacggtatg
    20881 gaagagaagg gcgcggacgc gtccgcgctg cgcacgatga gcgacgagga cttcgaggcg
    20941 ctggaggaga tcctcacctc ggacatcgtc cccgaggact gcatggacct cgagatgctc
    21001 gacggctacc tcgccggcgt gatgatctcg ccgcggccga tcgcgcccga gcgctggatg
    21061 cccggcgtgt ggtcggcgca cggcgacgag gtcggcttcg gctcgggcag cggcctgcag
    21121 cgcgcgatcc gcctggtgaa ggcgtatcac aacgaactgc tcgcgaccct gggcctggac
    21181 gacgaggacg aggcgtgctg ggagccgttc tgcttcgcgg tcgccgaggg cgacgggctc
    21241 aagctcgggg aggcctgggt ggacggcttc gcgcagggcc tggacctgtg gccggagggc
    21301 tgggaggagg gactggacgc ggaggcggtc gaggccgtgc gcgagaccct cgacgaggtg
    21361 ctcgcgccct ggggcgagga ggacgctgcc aaggccgacg acgagacccg cctgggctgg
    21421 ctcgccgacg tgggcgaggc ggtcaacgac atcttcgccc actggcgcga cctcggcctg
    21481 ccggccgccg agccgctgtc gaccgaggcc ccgcgcaagc ccgccagcgc cacccccggc
    21541 cgcaacgacc catgcccctg cggcagcggc aagaagtaca agaagtgctg cggcgccaac
    21601 ggcgccgagg c
//
LOCUS       DAOTIN010000051        21274 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_2969_length_21274_cov_8.601254, whole genome shotgun sequence.
ACCESSION   DAOTIN010000051 DAOTIN010000000
VERSION     DAOTIN010000051.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 21274)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 21274)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21274
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2969_length_21274_cov_8.601254"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..356
                     /locus_tag="P5537_09325"
     CDS             <1..356
                     /locus_tag="P5537_09325"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004379591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HRV78281.1"
                     /translation="LFLFPSLTETFGNVTLEAMASGVCPVAYDYAAAAEVIRDLGNGA
                     SVACGDEEGFIARAVQMAGADALRAELARAARHSAEAIDWERVNDHFAAALLRVWRVG
                     SGLPVELSEPRPEEA"
     gene            360..1214
                     /locus_tag="P5537_09330"
     CDS             360..1214
                     /locus_tag="P5537_09330"
                     /EC_number="3.6.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-2,3-diacylglucosamine diphosphatase"
                     /protein_id="HRV78282.1"
                     /translation="MSSVRAIFLSDVHLGTRACQAERLLDFLREHESDYLYLLGDIVD
                     FWAMKRSVQWAPSHNTVVQKVLRRARHGCQVIFIPGNHDEALREHAGIAFGDIRVESE
                     WIHQTADGRRYWLVHGDEYDQVTRHHRWVALLGDVAYNALVRLNLLLSRARRLLGVSG
                     YWSLAGYAKQKVKKAVSFIFDFEDAVAHAAQQRGVDGVICGHIHWASDRRIGDIRYLN
                     CGDWVDSCSAVVEHHDGRIEVLQWGVQGAHALAALPAPPAPARPPLPPRAAPLPAGAE
                     RIYLMPDI"
     gene            complement(1367..1576)
                     /locus_tag="P5537_09335"
     CDS             complement(1367..1576)
                     /locus_tag="P5537_09335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78283.1"
                     /translation="MKLSRLYRPQDRRFWLMIVLNLLSAVLAWFLRSWPLVPLATVVV
                     ALFALGNAALGMFIAWDLLRDERED"
     gene            1782..3833
                     /locus_tag="P5537_09340"
     CDS             1782..3833
                     /locus_tag="P5537_09340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HRV78284.1"
                     /translation="MLRLRPLAVAVLGLSALPVSSLVLAETMLGAQTVTAKGYAADTL
                     ETPQAVEILQAPAAGGTVAGELLRGKPGLAAQSDGAWGQNPVLRGLKKESVVVMVDGV
                     RMNSAQPQGAIASFLDLGLLERAEVVKGPGSVLYGSGAMGGVVNLITPDVGFTAEEKL
                     GGRIGARFSSVDKGVAGAALLTRSSANSALVLGVAGRDVDDYRSPDGREDHTGYRSDT
                     LLAKYKHKVTEDLTLRVNLQRHEDEDVWYPGSARRGAGIPAPLGTATIHSPEQRRELY
                     ELGVDARLGEGTLAAEVYRQEVFRQIRAFSSAKQRDYVRNDVSFVTDGAKAKYLFPVG
                     DDHLLTVGADLWRMRGDPERYIDNNPPAFDNNMRNDPFNKGVIESAGVFLQDEFSVGQ
                     TRFIAGARFDRVTGDAARKGMTQTTGLEKSDNNLSWSLGAIQPLNENLSAYANLGRAY
                     RAPDMRERFEDSARGDGYYHVGNPQLDPEVSTSFELGLRQAGAGLQYQLAAFYTRIDD
                     YIAGRVTGANHPQNGLPFKLTENLDKVTIYGLEGSASLPVGAFVADAGFTWLRGKNHQ
                     DDEPLFQMPAPELTLGIGQPAERGFWWRAQLRAVAEQDRIATRFTNGTENATAGFVTA
                     DAEFGWRFGKVGAFESAGLAVQLSNLADKRYHEHQTEGVSGNELAAPGRGIALSLNGS
                     F"
     gene            4015..5007
                     /locus_tag="P5537_09345"
     CDS             4015..5007
                     /locus_tag="P5537_09345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhnD/SsuA/transferrin family substrate-binding
                     protein"
                     /protein_id="HRV78285.1"
                     /translation="MHVCVVCAFLLVTGIVHAQAQKLPKLTLAGPSAAVSNALIHMVD
                     SGALADIAEVVEFVPWRDPDQLRVMALDGRADVLAMPTNVAANLYNRGAKLQLINVST
                     WGVLWLVSRDPALKSLADLRGKELAMPFRGDMPDIVLQLLAEQQGMDVKKDLQLRYVA
                     SPVDAMQLLVMRRVDHALLAEPAASMALRKTGSFPLSLVAPELHRSVDLQQEWGRVFA
                     RTARIPQAGIAVMGALRERPELVARIETEYARALKWCKDNAEACGKAVAARIDLLSPE
                     AVKDSIAVSQLEAVSVADARAELEFMFGKLVAKNPALVGGKLPDEGFYAGATKR"
     gene            5004..5795
                     /locus_tag="P5537_09350"
     CDS             5004..5795
                     /locus_tag="P5537_09350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HRV78286.1"
                     /translation="MTLLRAWLAGLPAYLWSGWGAIASLFLLLAAWEAVSLVYGALVM
                     PDPRSAFATLWGLIDSGAAWPELAATARRALTGYALSVVAGSLLGLVAGLSMTASMMS
                     RPLVTVLMGTPPIAWLVLAMLWFGASDGTPVFTVFVASFPVIFIGALQGTRTLDNQLH
                     GMAEAFRLPRRMMITDVYLPHVVSYLFPAWIAALGTAWKVVVMAELLATQDGVGAALA
                     VSRSHLDTAATMAWIAAVVGLLLAVEYLVLEPIKREVERWREQGA"
     gene            5792..6700
                     /locus_tag="P5537_09355"
     CDS             5792..6700
                     /locus_tag="P5537_09355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004356681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HRV78287.1"
                     /translation="MNPVSRAELRVHGLSHAFARDEVLSGIHFRVRAGEVVALVGPSG
                     CGKTTLLHLAAGLLTVQEGRVDNGFASTAFMFQQPRLLPWKTALDNVALGLKAGGMKR
                     AERHFRARELALRLGLAHRDLDKFPHQLSGGMQSRVALARALVLAPELLLLDEPFSAL
                     DVGLKEELYRLLLDHQAERGMGVLMITHDLMEAVRLSDAILVMAPEPGRIVCRFELDH
                     PPARRGDAWVYRHTAELLQTPEVRASFGLPAAVEAEGTGPAQRDGVLRPGGSQGGGRV
                     EPLSGLRLVSPASGLVAVQGGKRCGA"
     gene            6787..8112
                     /locus_tag="P5537_09360"
     CDS             6787..8112
                     /locus_tag="P5537_09360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NnrS family protein"
                     /protein_id="HRV78288.1"
                     /translation="MAARPLFMCGFRPFFVLTAFYAVLALLLWGGFLGFGLAVPAVAG
                     GPFVWHAHELMFGFGLAAVAGFVLTAVPEFTATPAFAPRVVVRFVLLWLAARAAFWLS
                     GGLAVVAGGWLGGADGHAAAHWIGHAPAALLNIGFACALLAAVAPRLWRDPERRQLGF
                     LWGLAAMAVAVAGFHLDVLRGGYPMRWVLAGLGVMMTLVVVAMSRISMRIMNDALDAE
                     RARRLPAHTLRHDEEAELELPSYRARPPRRNLAIAAIATYTVAEFLLPGSPITGWLGL
                     GAAAAVFNLLNDWHVGRALFTRWAFFLYAVYWLLALGYLLLGLAHLGAPLAPSAGTHL
                     LAIGAMGLSILAVLCIAGRTHAGHPLDERPWVVVAAVSIALAAVLRAASGLPDMPAFA
                     LQLLAALAWVVAFTLAAWRLGVLFVAARVDGGTGCDEYHEPGAPQRAPT"
     gene            8267..8710
                     /locus_tag="P5537_09365"
     CDS             8267..8710
                     /locus_tag="P5537_09365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004383418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriohemerythrin"
                     /protein_id="HRV78289.1"
                     /translation="MALLNWKADYCTGNAKIDDDHCNLFERINDFHFAWQSSRDRKDI
                     ARVLNRLVEYAEEHFAREEEIMRASGYPGLARHHAIHEALFEQIFVLQGHFEDGRIRI
                     DRDAVDFLRGWLVDHIVGEDMKFSAYVEGGVDPAPASRAIDIDVV"
     gene            complement(8746..9948)
                     /locus_tag="P5537_09370"
     CDS             complement(8746..9948)
                     /locus_tag="P5537_09370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HRV78290.1"
                     /translation="MTGPHLLPLLLLYALMLPVTGMVPVLPDFTAQRFPGLGQFASHF
                     FMSINMIGALLGAPIAGLLSDRLGKRRLLAVGALAANGVALLGIAWAWHAAESYALLL
                     ALRFVEGFAHMSALSLLMALAADHAGRAGLGARMGAVGASISLGVATGAPLGGVIGGI
                     DPFWVPFGGGLLSLAMAALGFVRLAEGGGTRPRMAAAAIVGTLRSRRQLLIPLAFSFA
                     DRLTVGFIVSTLSLYLGLVIGFDARQIGIAMAAFLIPFSVLTWPAGHLSRHWDPLWMM
                     VIGSVLYGVFLAVLGFVPGDRVVATMAAGGVIAALMYAPSLVLAAQYGGSDCRASALA
                     AFNMAGSLGFATGPLLSSALLAVFGLLLDRPYPPVFVAIGLIEVVLALAVLVMARRGR
                     LQAGAASA"
     assembly_gap    10231..10330
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            10627..11103
                     /locus_tag="P5537_09375"
     CDS             10627..11103
                     /locus_tag="P5537_09375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78291.1"
                     /translation="MRAVYLSGLLVVVLAAITFWMVSDLQPGVIVLQFAWTPRGFGEI
                     VHVWPPEDLERYRLHLPLDSLLLLAYGSFGWLLATRTALFASLPRLACAAAPFVLPLA
                     AAFDAVENALHAWLTEMPRFGLHSLYLLSTSCSALKWALLFGFGALVLWALAREAD"
     gene            complement(11109..11897)
                     /locus_tag="P5537_09380"
     CDS             complement(11109..11897)
                     /locus_tag="P5537_09380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mut7-C RNAse domain-containing protein"
                     /protein_id="HRV78292.1"
                     /translation="MSDATPAPLSPACLVYFRFHGELATFIAPARRGRVFEVRCATDA
                     SIKHVIEALGVPHTEVGTLQVDGRPARLDGRLRPGERVEVHPHSALRQAPCPSTPARF
                     IADAHLGGLARLLRLAGFDTLYDNHIEDAALVATAVREQRVVLTRDRELLKRRDVAEG
                     CFVHALAPEQQAVEIIRRLGLAPHARPFSRCLECNAALQEVVSPAAAEQRVPPAVRAR
                     HTRFSACPGCGRVYWEGSHWARMRARIDALLAHAHAAPGDEAAD"
     gene            12001..12252
                     /locus_tag="P5537_09385"
     CDS             12001..12252
                     /locus_tag="P5537_09385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78293.1"
                     /translation="MKTPALFVTLSGLSATALAVLVLAAIPAPAGAIAQPAAPALPEE
                     CVCSRGLRLAEAPPSVLHNCQCGPLQCVVHAQSGQLQCR"
     gene            12243..12746
                     /locus_tag="P5537_09390"
     CDS             12243..12746
                     /locus_tag="P5537_09390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004387255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1810 domain-containing protein"
                     /protein_id="HRV78294.1"
                     /translation="MPLTAGDPHDLARFVEAQRGVHADALAELRAGRKRSHWMWFVFP
                     QLAGLGTSPTAQRYGVRSLDEASAYLAHPLLGARLRECAQALLALRGRSAEQVFGYPD
                     VLKLRSSMTLFAAVPGADPVFGEVLARYYGGQADERTLHLLGQGAGRMRIPGLPAGSG
                     HGREERE"
     gene            12743..13168
                     /locus_tag="P5537_09395"
     CDS             12743..13168
                     /locus_tag="P5537_09395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HRV78295.1"
                     /translation="MTPRISVITLGVDDLERAVAFYRDGLGWPTRGIVGSAEQHSAVA
                     FFALQPGIQLALFPRASLAVEVGVARPRAGTSACLLSHNVARREQVAAVMAQAEAAGA
                     RILRAPHDTAWGGYAGYFQDPEGHPWEVAWNPKWPVEDD"
     gene            13325..14491
                     /locus_tag="P5537_09400"
     CDS             13325..14491
                     /locus_tag="P5537_09400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HRV78296.1"
                     /translation="MPSSRRLVLSLSLVGLAALGAYAWYANRPPAALPGGAQPAGTQA
                     GPSAAGTPGAKAPAGGAGGAQPGPVVVETHTVGVRALAEDIGAVGSLVSNESVVLRPE
                     VSGRIEAIRFRDGESVRRGEVLIEFDAAVQRAELQQARASLTLAESNFRRSQDLFSRS
                     FVSRSSLDNARSQLEVARAGVALAQAKLARMQIRAPFAGVVGIRSVSPGDFVKDGEAM
                     INLEDIATLKVDFRLPELYLDRVRPGQAVEIASDVLAGERFAATVEAIDPLVDAQGRA
                     LRLRASLPNPELRLRPGVFVRVRLILAERADVVVVPEAALVPAPGNIQFVYRVADGKA
                     QRVEVRTGVRRDAMVEVVEGVQAGEVVVTAGQLKLRDGAAVKVAGAPAGVARAD"
     gene            14495..17566
                     /locus_tag="P5537_09405"
     CDS             14495..17566
                     /locus_tag="P5537_09405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HRV78297.1"
                     /translation="MVLSELCIRRPVFATVLSLLVLLVGLMSYSRLTVREYPNIDEPV
                     VTVDTTYRGASAEIVESQVTKPLEDSLAGIEGVDVLSSISRQERSQITVRFRVERDAD
                     SAAADVRDRVSRVRQRLPDDIDEPVIAKVEADASPIIWVAFSSDRHSPMEISDFANRI
                     IKPRMQTLPGAADARLYGERRQAMRVWLDRDRLAAFGLTVQDVEDAIRRQNVELPAGR
                     IESREREFAVVAQTDLVEPAQFEAIVLRQGDTADAYPVRIRDVGRVEVAPESERTAVR
                     FMGRPAISIGLIKQSVANPLDLKRGLDEMLPRLQAELPEGMSMKIANDTTVFIERSIE
                     AVFSTIWEAVLLVAAVCLFFLRNWRAMLVPLVTIPVSLVGAFTLMLVFGFSINTLTLL
                     ALVLAIGLVVDDAIVVLENIYRHIEEGMEPLAAAFRGAKEIGFAVVAMTITLAAVYAP
                     VAFMSGRTGKLFTEFALTLAGAVIVSGFVALTLSPMMCSKLLRHEPRHGPIYNGIERF
                     LGWLTRGYRGVLGAALHVRWLVMLVFAAVAGSSVWLMGQLKTELAPLEDRGRVIGMFS
                     GPEGATLDYMARYAEEIERIYAGLPEVDRYMVIAGNPTVSQGISFVGFTDWAERSRKA
                     GAISAELQPKLRAVPGVNAFPILPASLGQSVRSRPVSFVVSTSESYDELARVAEAFLD
                     EMRRNPGLVSPDTDLKLTMPELAVQVDRDRAADLGVAVDVIGRTLESMLGGRQVTRYK
                     QDAEQYDVIVQVAADERRDPRDIRDIYVRARDGRMVPLTSVVQVDERVAPRELNHFGQ
                     RRSVTITANLAPGYALGEALGWMEDTAARILPPGYGTDYDGQSREFKTSSESLALVFL
                     LALAFIYLVLAAQFESFRDPFIIMLTVPLSMTGALGALWLTGGTLNVYSQIGLVTLVG
                     LITKHGILIVEFANQLREQGRALREAVTEAAVLRLRPILMTTGAMVLGSVPLALATGA
                     GAESRQQIGWVIVGGLTIGTFFTLFVVPTVYTLLARRERAAQAGIVQGSAA"
     gene            complement(17629..17850)
                     /locus_tag="P5537_09410"
     CDS             complement(17629..17850)
                     /locus_tag="P5537_09410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcH family protein"
                     /protein_id="HRV78298.1"
                     /translation="MFPEYRDLITRLKHNDRHFTQLFEKHNELDEKVHNIETHIVPAS
                     DHELEVMKKEKLLIKDQIYAYLKKVAAES"
     gene            complement(18065..18610)
                     /locus_tag="P5537_09415"
     CDS             complement(18065..18610)
                     /locus_tag="P5537_09415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004378041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1415 domain-containing protein"
                     /protein_id="HRV78299.1"
                     /translation="MDEQIIADVEQWLDEVVIGLDLCPFAARPRREKRVRIAVSHATT
                     AEALLDDLQAELERLSDTPVAELETTLLAIPDMLEDFADYNDFLDAVDLWVEQFGWEG
                     ELQVASFHPHYQFADTEADDPGNLTNRSPWPLLHIIREESLEKAIEHYPDVDRIPERN
                     IARMQALTAEERAKLFPHLFG"
     gene            complement(18626..19633)
                     /gene="miaA"
                     /locus_tag="P5537_09420"
     CDS             complement(18626..19633)
                     /gene="miaA"
                     /locus_tag="P5537_09420"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HRV78300.1"
                     /translation="MPTEAPPALTPSPALTLPPALLLLGPTASGKTASALALAQALPV
                     EVISVDSALVYRDMDIGTAKPSAEERAVCPHHLIDVVSPEENYSAARFRADAIRLMGE
                     IVARGNLPLLAGGTMLYFKALRDGLSDLPAADPELRRALDDEAAERGWPALHAELARL
                     DPEAAARLEPGDAQRIQRALEIVRLTGRPLADSYAKKEDEPLPCRLLPIALAPSDRGV
                     LHKRIEERFDAMLHAGLVDEVRQLRARYRLDPSMPSMRCVGYRQVWEYLDGGTGYDEL
                     RFKGIAATRQLAKRQLTWQRQFRETWPGFVELDCLRPDLPEAVLHTALRLLHDLPLHT
                     A"
     gene            complement(19716..20417)
                     /locus_tag="P5537_09425"
     CDS             complement(19716..20417)
                     /locus_tag="P5537_09425"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="PEP-CTERM proteins occur, often in large numbers,
                     in the proteomes of bacteria that also encode an
                     exosortase, a predicted intramembrane cysteine proteinase.
                     The presence of a PEP-CTERM domain at a protein's
                     C-terminus predicts cleavage within the sorting domain,
                     followed by covalent anchoring to some some component of
                     the (usually Gram-negative) cell surface. Many PEP-CTERM
                     proteins exhibit an unusual sequence composition that
                     includes large numbers of potential glycosylation sites.
                     Expression of one such protein has been shown restore the
                     ability of a bacterium to form floc, a type of biofilm;
                     Derived by automated computational analysis using gene
                     prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-CTERM sorting domain-containing protein"
                     /protein_id="HRV78301.1"
                     /translation="MKIRKQFIAAALLAAGLGAGLAHATPISLTKLGGTTGGTIAATA
                     VFRADLSTAAIGTLQSITIRDNSAGLGGSPGRFSGFDLDAIILSSDSCDTANCVAGLS
                     PLSAFNYSSGVIFTPGVQRDPADPKLFGTGPTGSTVDNAVATLGLFDGESTAGSGADG
                     FLSLGDGGRISFNLSSALSTSGLYLYLGEVGDNGEALAGEITISQNPVPEPVSLSLLA
                     IGLAGLGIGRRARRA"
     gene            complement(20688..21254)
                     /locus_tag="P5537_09430"
     CDS             complement(20688..21254)
                     /locus_tag="P5537_09430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019919648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FlgO family outer membrane protein"
                     /protein_id="HRV78302.1"
                     /translation="MMRTPAILAAALSATVLVTTGCATEPVAQRKEVSFDAAAANPLI
                     PSNYAAADSLLAQLRGQLAPAQALIAATVVNIDALEQSSTLGRLISEQVSARFTLAGY
                     RMVEMKFRNNVYMARDQGELMLTREIRDLASSHDAQAVVVGTYAQSSELVFVNLKVIQ
                     PETNVVLAVHDYALPLDSMTRSMLRGSR"
BASE COUNT         2975 a         7095 c         7788 g         3316 t
ORIGIN      
        1 acctgttcct atttcccagc ctcaccgaga ccttcggcaa cgtcaccctc gaggcgatgg
       61 cgagcggggt gtgcccggtg gcctacgact acgccgccgc ggccgaggtg atccgcgacc
      121 tcggcaacgg cgccagcgtg gcctgcggcg acgaggaggg cttcatcgcg cgcgccgtgc
      181 agatggccgg ggccgatgcg ctgcgcgccg agctcgcgcg cgccgcgcgc cacagcgccg
      241 aggcgatcga ctgggagcgg gtgaacgacc acttcgccgc ggccctgctg cgcgtatggc
      301 gggtcggcag cggcctgccc gtcgagctgt ccgaaccccg cccggaggag gcctgaacca
      361 tgagcagcgt gcgcgcgatc ttcctctccg acgtccatct cggcacccgc gcctgccagg
      421 ccgagcgcct gctcgacttc ctgcgcgagc acgagtcgga ctatctctac ctgctcggcg
      481 acatcgtcga cttctgggcg atgaagcgca gcgtgcagtg ggcgcccagc cacaacacgg
      541 tggtgcagaa ggtactgcgc cgcgcccgtc acggctgcca ggtgatcttc attcccggca
      601 accacgacga ggccttgcgc gagcatgccg gcatcgcctt cggcgacatc cgcgtcgagt
      661 cggaatggat ccaccagacc gccgacggcc ggcgctactg gctggtgcat ggggacgagt
      721 acgaccaggt cacccgccat catcgctggg tggcgctgct gggcgacgtc gcctacaacg
      781 cgctggtgcg gctcaacctg ctgctgtcgc gcgcgcgccg cctgctcggc gtgtccggct
      841 actggtcgct tgccggctat gccaagcaga aggtcaagaa ggcggtgagt ttcatcttcg
      901 acttcgagga cgcggttgcc catgccgcgc agcagcgcgg ggtggacggg gtgatctgcg
      961 gccacatcca ctgggcctcg gaccgccgca tcggcgacat ccgctacctc aactgcggcg
     1021 actgggtgga tagctgcagc gccgtggtcg aacaccacga cggccgcatc gaggtgctgc
     1081 agtggggcgt gcagggcgcg cacgcgctcg cggcgctgcc ggcgccgccc gcgcctgcac
     1141 gtccgcctct tcccccgcgc gccgcgccgc tgccggcggg cgccgagcgc atctacctga
     1201 tgccggacat ctgagcccgt tacgcctctc ggccgtcgca ttcgcgcctt gcggcgctcc
     1261 tacagaaagt cgccgcgctt cgtgccgatg caggagcgcc tcaaggcgcg aacatggccg
     1321 ccgagatgta ccgcttcccg cggggtaggg ccagcggcca ggcgactcaa tcctcgcgct
     1381 cgtcgcgcag caggtcccag gcgatgaaca tgcccagcgc ggcgttcccc agcgcgaaca
     1441 gcgccaccac caccgtcgcc agcggcacga gcggccagct gcgcaggaac caggcgagca
     1501 cggcggagag caggttgagc acgatcatca gccagaagcg gcgatcctgt gggcggtaga
     1561 ggcgggagag cttcatcggc ttgaggcggg gaggtcggga agacgggctg gaagcgcatg
     1621 atagcgggga cggactgcaa gccggggtgt ctgcggggaa tttgataaaa agcaaatgcg
     1681 aacgattcgc attgttgtat cattgcttcc tgatcttcct gttcgggcaa gccagccgtc
     1741 gccagccagc ccgggaaccc gacttcctgg agctttccat cgtgcttcgt ctgcgcccgc
     1801 tcgcggtggc cgtcctcggc ctgtccgccc tccccgtttc cagcctcgtc ctcgccgaga
     1861 ccatgctcgg cgcccagacc gtcaccgcca agggctacgc cgccgacacc ctggagacgc
     1921 cccaggcggt cgagatcctg caggcgccgg cggccggcgg cacggtcgcg ggcgagctgc
     1981 tgcgcggcaa gcccggcctc gcggcgcagt ccgacggcgc ctgggggcag aacccggtgc
     2041 tgcgcgggct caagaaggag agcgtggtgg tgatggtcga cggcgtgcgc atgaactccg
     2101 ctcagccgca gggcgcgatc gcctccttcc tcgacctcgg cctgctcgag cgcgccgagg
     2161 tggtcaaggg cccgggctcg gtgctgtacg gcagcggcgc gatgggcggg gtggtcaacc
     2221 tgatcacgcc ggacgtcggt ttcacggccg aggagaagct cggtggccgc atcggcgcgc
     2281 gcttctcgag cgtggacaag ggcgtcgccg gcgctgcgct gctgacgcgc tcgagcgcga
     2341 acagcgcgct ggtgctgggg gtggccgggc gcgacgtcga cgactaccgc agcccggacg
     2401 gccgcgagga ccataccggc taccggtccg acacgctgct ggcgaagtac aagcacaagg
     2461 tgaccgagga tctgacgctg cgggtgaacc tgcagcggca tgaggacgag gatgtgtggt
     2521 atccggggtc ggcgcgccgc ggtgcgggaa ttcctgcgcc gctcggcacc gccacgatcc
     2581 actcgcccga gcagcgccga gagctgtatg aactgggcgt ggatgcgagg ctgggtgaag
     2641 gaacgctggc ggccgaggtc tatcgtcagg aggtcttccg ccagattcgc gccttctctt
     2701 cggccaagca acgcgactac gtgcgcaacg acgtcagctt cgtcaccgat ggcgcgaagg
     2761 cgaagtatct gtttccggtc ggagacgacc acctgctgac ggtgggtgcc gacctgtggc
     2821 gcatgcgtgg ggaccccgag cgctacatcg acaacaatcc cccggccttc gacaacaaca
     2881 tgcgcaacga tcccttcaac aagggcgtga tcgaatctgc gggcgtgttc ctgcaggacg
     2941 aattctcggt cggccagacc cgcttcatcg cgggcgcacg cttcgaccgc gtgacgggag
     3001 acgccgcgcg caagggcatg acgcagacca ccggcctcga gaagtccgat aacaacctgt
     3061 cctggtcgct cggcgcgatc cagccgctga acgagaacct gagcgcctac gccaacctcg
     3121 gtcgcgccta tcgcgcgccg gacatgcgcg agcgcttcga ggattcggcg cgtggcgatg
     3181 gctactacca cgtcggcaat ccgcagctcg atccggaggt gtcgaccagc ttcgaactgg
     3241 gcctgaggca ggctggcgca ggcttgcagt accagcttgc cgccttctac acgcgcatcg
     3301 acgactacat cgccggacgg gtcaccgggg cgaaccatcc gcagaacgga ctgcccttca
     3361 agctcactga gaatctcgac aaggtcacga tctacggcct ggagggcagc gccagcctgc
     3421 cggttggcgc cttcgtcgcc gacgccggct tcacctggct gcgcggcaag aaccaccagg
     3481 acgacgagcc gctgttccag atgccggcgc ccgagctgac cctcggaatc ggccagcccg
     3541 ccgagcgcgg cttctggtgg cgggcgcagt tgcgtgcggt ggccgagcag gaccgcatcg
     3601 ccacccgctt caccaacggt acggaaaacg ccaccgccgg cttcgtcacc gccgacgccg
     3661 agttcggctg gcgctttggc aaggtcggtg ccttcgagtc cgccggcctt gccgtgcagc
     3721 tcagcaacct ggccgacaag cgctaccacg agcaccagac cgagggcgtc tcgggcaacg
     3781 agctcgccgc gcccggccgc ggcatcgcac tgagcctgaa cgggagcttc tgacatgcac
     3841 gaccgccgcc ccagccacgc gcccgcggac catcatgcga acccgccacg cggcgtcgtg
     3901 ttcgtcgatc gctcggcccg ccgcctcgca tgcgagggcc gtcccgacgt gggggcgggg
     3961 gctgcgatcc ggccgcgccg cggcttcgcc ctgccggcat ggacgcgcgc ggtcatgcac
     4021 gtctgcgtgg tgtgcgcctt cctgctcgtg accggcatcg tgcacgcgca ggcgcagaag
     4081 cttcccaagc tcaccctcgc cggtccctcg gccgcggtgt cgaacgcgct catccacatg
     4141 gtcgattcgg gcgcgctcgc ggacatcgcc gaggtggtcg agttcgtgcc ctggcgcgac
     4201 cccgaccagc tgcgcgtgat ggcgctcgac gggcgcgccg acgtgctggc gatgcccacc
     4261 aacgtcgccg ccaacctgta caaccgcggc gccaagctgc agctgatcaa cgtatcgacc
     4321 tggggcgtgc tgtggctggt gtcgcgtgac ccggcgctga agtcgctcgc cgacctgcgc
     4381 ggcaaggagc tggcgatgcc tttccgcggt gacatgcccg acatcgtgct gcagctgctg
     4441 gccgagcagc agggcatgga cgtgaagaag gacctgcagc tgcgctacgt cgccagcccg
     4501 gtggatgcga tgcagctgct ggtgatgcgc cgcgtcgacc atgcgttgct cgccgagccg
     4561 gcggcctcga tggcgctgcg caagaccggg tccttcccgc tcagcctggt cgcgcccgag
     4621 ctgcatcgca gcgtggacct gcagcaggag tgggggcggg tgttcgcgcg cactgcgcgc
     4681 atcccgcagg ccggcatcgc ggtcatgggg gcgctgcgcg agcgccccga gctggtggcg
     4741 cgcatcgaga ccgagtacgc gcgcgcgctg aagtggtgca aggacaacgc cgaggcctgc
     4801 ggcaaggcgg tggcggcgcg catcgacctg ctgagccccg aggcggtgaa ggactcgatc
     4861 gcggtgagcc agctcgaagc ggtgtccgtt gcggatgcgc gcgccgagct cgagttcatg
     4921 ttcggcaaac tggtggcgaa gaacccggcc ctggtcggcg gcaagctgcc ggacgagggc
     4981 ttctacgccg gagcgacgaa gcgatgaccc tgctgcgcgc ctggctggcc ggcttgccgg
     5041 cttacctgtg gagcggctgg ggcgcgatcg ccagcctctt cctgctgctc gccgcctggg
     5101 aggcggtgag cctcgtttac ggcgcgctgg tgatgcccga cccgcgctcg gccttcgcca
     5161 cactgtgggg cctgatcgac agcggcgcgg cctggccgga gctggccgcc accgcgcgcc
     5221 gcgcgctcac cggctatgcg ctgtcggtgg tcgccggcag cttgctcggc ctcgtcgccg
     5281 ggctgtcgat gaccgcctcg atgatgtcgc gcccgctcgt caccgtgctc atgggcacgc
     5341 caccgatcgc ctggctggtg ctggcgatgc tgtggttcgg cgcgagcgac gggacgccgg
     5401 tgttcacggt gttcgtggcg tccttcccgg tgatcttcat cggcgcgctg cagggcacgc
     5461 gcacgctcga caaccagctt cacggcatgg ccgaggcctt ccgcctgccg cggcgcatga
     5521 tgatcaccga cgtctatctg ccgcacgtgg tgtcctacct gttcccggcc tggatcgccg
     5581 cgctcggcac ggcgtggaag gtggtggtga tggccgagct gctcgccacc caggacggcg
     5641 tgggcgcggc gctcgcggtg tcgcgctcgc acctcgacac ggccgccacc atggcctgga
     5701 tcgccgcggt ggtcggcctg ctgctagcgg tggagtacct ggtgctggaa ccgatcaagc
     5761 gcgaggtcga gcgctggcgg gagcagggcg catgaatccg gtgtcccgcg cggaactgcg
     5821 cgtccatggt ctttcccacg cgttcgcccg cgacgaggtg ctctccggca tccacttccg
     5881 cgtgcgcgcg ggcgaggtcg tggccctggt cggcccctcg ggctgcggta agaccacgct
     5941 gctgcacctc gctgcgggcc tgctgacggt gcaggagggg cgcgttgaca acggcttcgc
     6001 ctccaccgcc ttcatgttcc agcagccgcg cctgctgccg tggaagacgg cgctcgacaa
     6061 cgtcgcgctc gggctcaagg cgggcgggat gaagcgcgcc gagcgccact ttcgcgcgcg
     6121 ggagctggcg ctgcgcctcg ggctcgccca tcgcgacctc gacaagtttc cccaccagct
     6181 ctcgggcggc atgcagagcc gggtggcgct ggcgcgcgcg ctggtgctcg cgcccgagct
     6241 gctgctgctc gacgagccgt tctcggcgct cgacgtcggc ctcaaggaag aactctatcg
     6301 ccttttgctc gaccatcagg ccgagcgcgg catgggcgtg ctgatgatca cccacgatct
     6361 catggaggcg gtgcgcctgt cggacgcgat cctggtgatg gcgcccgagc cggggcgcat
     6421 cgtgtgccgc ttcgagctcg accatccgcc ggcccggcgc ggtgacgcct gggtgtatcg
     6481 gcacaccgcc gaactcctgc agacgccgga ggtgcgtgcg agcttcggcc tgccggcggc
     6541 ggtggaagcg gagggaacag gccctgcgca gcgcgatggg gtcttgcgac caggcgggtc
     6601 gcagggtggc ggacgcgtgg agccgctgtc cggtctgcgc ctggtgagcc ccgcttccgg
     6661 gctggtcgcg gtgcagggcg gcaagcgctg cggggcatga gcatgggtga cacgacgatg
     6721 aacgcagaag gcaggcttgc gacggggagc ggggcggaaa gcgcgcagcg gcactggagc
     6781 gcacgcgtgg cggcgcggcc gctgttcatg tgcggcttcc ggccattctt cgtgcttacc
     6841 gcgttctacg cggtgctggc gttgctcctg tggggcggct tcctcggctt cggcctggcg
     6901 gtcccggcgg tcgcgggcgg acccttcgtg tggcacgctc acgagctgat gttcggcttc
     6961 gggctcgcgg ccgtggccgg tttcgtactc accgcggtgc ccgagttcac cgccacgccg
     7021 gccttcgcgc cacgggtggt ggtgcgcttc gtgctgctct ggctggcggc gcgcgcggcg
     7081 ttctggctgt cgggcgggct cgcagtcgtc gccggcggct ggctcggtgg ggccgacggc
     7141 cacgccgctg cgcactggat cgggcatgcg cccgcagcgc tgctcaacat cggcttcgcc
     7201 tgcgcgctgc tggctgcggt ggcgccgcgg ctatggcgcg atcccgagcg gcgccagctc
     7261 ggattcctgt ggggcctggc ggcgatggcc gtcgcagtgg cgggcttcca cctcgacgtg
     7321 ctgcgcggcg ggtacccgat gcgctgggtg ctggcggggt tgggcgtgat gatgacgctg
     7381 gtggtggtgg cgatgagccg gatctcgatg cgcatcatga acgacgcgct cgacgccgag
     7441 cgtgcccgcc gcctgcccgc gcacaccctg cgccacgacg aggaggccga gctcgagctg
     7501 ccctcgtacc gtgcgcggcc accgcggcgc aacctggcga tcgcggcgat cgcgacctac
     7561 acggtggccg agttcctcct gccgggctcg ccgatcaccg gctggctggg gctgggcgcg
     7621 gctgcggcgg tgttcaacct gctcaacgac tggcacgtcg gacgcgcgct gtttacgcgc
     7681 tgggccttct tcctctatgc ggtgtattgg ctgctcgcgc tcggctacct gctgctcggt
     7741 ctcgcccatc tcggcgcgcc gctggcgccg agcgccggga cccacctgct cgcgatcggc
     7801 gcgatgggcc tgtccatcct ggcggtgctg tgcatcgccg ggcggacgca cgcaggccat
     7861 ccgctcgacg agcgcccgtg ggtggtcgtg gcggcggtgt cgatcgcgct cgcggcggtg
     7921 ctgcgcgcag cctccggcct gccggacatg cccgccttcg cgctgcaact gctcgccgcg
     7981 ctcgcctggg tcgtggcctt cacgctcgca gcgtggcggc tgggcgtgtt gttcgtggcc
     8041 gcgcgggtgg atggcggaac cgggtgcgac gagtatcacg agcctggcgc gccgcagcgc
     8101 gccccgactt gatctcgatc gaggcccggc gtgattgcgc cgggcccgcg ccgggtccgc
     8161 gcaggctggc gtgagcgggt tcgtggcggc gcgggtgtgg aacgcgttaa gctgagggcc
     8221 atggacggtt ccggcgagga ggccgtccga tcccggagaa ccgacgatgg cgctgctcaa
     8281 ctggaaagcc gactattgca ctggtaacgc gaagatcgac gacgatcact gcaatttatt
     8341 cgagcgtatc aacgatttcc acttcgcctg gcagagcagc cgcgaccgca aggacatcgc
     8401 ccgcgtgctc aaccggctgg tcgagtatgc ggaagagcac ttcgcgcgcg aggaggagat
     8461 catgcgcgcc agcggctacc cgggactggc gcgccatcac gcgatccacg aggcgctgtt
     8521 cgagcagatc ttcgtgctgc agggccactt cgaggacggg cgtatccgca tcgaccgcga
     8581 tgcggtcgat ttcctgcgcg gctggctggt cgatcatatc gtcggcgagg acatgaagtt
     8641 ctcggcctac gtcgagggtg gggtcgatcc cgctccggcc tccagggcga tcgacatcga
     8701 cgtggtctga gggctgcgcc gggcgagccc ggatcgagtc gcgcctcagg ccgacgcggc
     8761 gccggcctgc aggcggccgc ggcgcgccat gacgaggacc gcgagcgcta gcacgacctc
     8821 gatcagtccg atcgccacga agaccggagg ataggggcga tcgagcagca ggccgaagac
     8881 ggcgaggagc gcgctgctga gcagggggcc ggtagcgaag ccgagcgagc cggccatgtt
     8941 gaaggcggcg agcgcgctcg cgcggcagtc gctgccgccg tactgtgcgg ccagcaccag
     9001 cgagggcgcg tacatcagcg ccgcgatcac cccgcccgca gccatcgtcg ccaccacccg
     9061 atcgcccggc acgaagccca gcacggccag gaagacgcca tagagcacgc tgccgatcac
     9121 catcatccac agtggatccc agtgtcgcga caggtggccg gccggccagg tgagtaccga
     9181 gaaggggatc aggaaggccg ccatcgcgat gccgatctgg cgcgcgtcga aaccgatcac
     9241 caggcccagg tagagcgaca gcgtcgatac gatgaagccc acggtgaggc ggtcggcgaa
     9301 ggagaaggcg agcgggatca gcagctggcg ccggctgcgc agggtgccga cgatcgcggc
     9361 cgcggccatg cgtgggcgcg tgccaccacc ctcggccagg cggacgaagc cgagcgcggc
     9421 catggcgagc gagagcaggc cgccgccgaa gggcacccag aacggatcga tgccgccgat
     9481 gacgccgccc aggggggcgc ccgtggccac gcccaggctg atcgaggcgc ccaccgcgcc
     9541 catgcgcgcg cccagcccgg cgcggccggc gtggtcggcg gcgagtgcca tcagcaagga
     9601 cagcgccgac atgtgggcga agccctcgac gaagcgcagc gcgagcagca gcgcgtagct
     9661 ctccgcagcg tgccaggccc aggcgatgcc gagcagcgcg acgccgtttg ccgcgagcgc
     9721 gcccaccgcg agcaggcggc gcttgccgag gcggtcggag agcaggccgg cgatcggggc
     9781 gccgagcagc gcgccgatca tgttgatcga catgaagaag tggctggcga actggccgag
     9841 gccggggaag cgttgggcgg taaagtcggg caggacgggc accatgccgg tgaccggcag
     9901 catgagggcg tagagcagca gcagcggcag gaggtggggt ccggtcatgg tgtcggcgcg
     9961 gggggcggcc tgcgcggtct tgggggtggt cgggtgcgcg gaatgatact tcgaccgccg
    10021 ccgcccgcat ctgttgccga tcaagccccg cctgtcctcg cgcccggcgg ccggaatcgc
    10081 gctgtctcgc gcagtagcgc ctcgattgcc ggagcgcagt gctcgcagct gccgcagctc
    10141 ctacaggcgg gccgggcgca tggtggttcc tgtaggagcg ccggcaggcg cgaaggcggc
    10201 ggtggagcgc gggacgcacg tcgcatgccg nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10321 nnnnnnnnnn ccgggacgcg cggtgattcc tgtaggagcg ccggcaggcg cgaaagcggc
    10381 ggtgcagcgc ggggcgcgcg tcgcatgccg gagcgcagtg ttcgcagctg ccggcgctcc
    10441 tacaggaaac cgccacgctt tagggggcgg caggcgcgaa ggcggcgtct ctccctttcg
    10501 gcgaacgtcc tttatccggc ccggcgtaga atccgctcgc tccgccagcg ccgccgtgag
    10561 cggctttgcg ggtcgtactg tcgctgcctt gttgcagctc tgctttcttg ccgcggaggt
    10621 tcgcgcatgc gcgccgtgta tctgtcgggc ctgctggtgg tcgtactcgc cgccatcacc
    10681 ttctggatgg tctcggactt gcagccgggc gtgatcgtgc tgcagttcgc gtggacgccg
    10741 cgcggcttcg gcgagatcgt ccatgtctgg ccgcccgagg atctcgagcg ctaccgcctt
    10801 cacctgccgc tcgacagcct gctgctgctg gcctacggca gcttcggctg gttgctggcg
    10861 acgcgcacgg cgctgttcgc gtccctgcct cggcttgcgt gcgctgcagc gcccttcgtc
    10921 ctgccgctcg cggcggcctt cgacgcggtg gagaacgcgc tgcacgcctg gctgaccgag
    10981 atgccgcgct tcggtctgca cagcctgtat ctgctatcga cctcctgctc ggcgctcaag
    11041 tgggcgctgc tgttcggctt cggcgcgctg gtgctgtggg cgctcgcgcg cgaggctgac
    11101 tgagacgctc agtccgcggc ttcgtctcct ggggcggcgt gcgcatgcgc gagcaacgcg
    11161 tcgatgcgcg cgcgcatgcg cgcccagtgc gagccttccc aatagacccg gccgcagccg
    11221 gggcaggcgg aaaagcgcgt gtgccgcgcg cgaaccgcgg ggggaacgcg ctgctccgcg
    11281 gcagcgggcg agacgacttc ctgcagggcc gcattgcatt cgaggcagcg cgagaacgga
    11341 cgggcgtgcg gggcgagtcc gaggcgccgg atgatctcga ccgcctgctg ctcgggcgcg
    11401 agcgcatgca cgaagcagcc ctcggcgacg tcccggcgct tgagcagctc gcggtcccgg
    11461 gtgagcacga cgcgctgctc gcgcacggcc gtggcgacga gcgcggcgtc ctcgatgtgg
    11521 ttgtcgtaga gggtgtcgaa gccggccagg cgcagcaggc gcgcgaggcc gccgagatgg
    11581 gcgtcggcga tgaaacgcgc gggcgttgag gggcagggcg cttggcgaag ggcggaatgc
    11641 ggatggacct ccacgcgctc gcccgggcgc agccgaccgt ccagccgcgc cgggcggccg
    11701 tcgacctgca gcgttcccac ctcggtatgc ggcaccccga gcgcttcgat cacatgcttg
    11761 atgctggcgt ccgttgcgca gcgcacctcg aagacgcggc cacgccgcgc gggggcgatg
    11821 aaggtcgcaa gctcgccatg gaagcggaag tagacgaggc aggcagggga gaggggcgcg
    11881 ggcgtggcgt cggacatggg caaggcattc ccccgatcca tcacggatgc agcatagcgc
    11941 gtcccgcgcc gcgtgcgctt gctgctacgc tgtgcgctgg ctcgtccgag gagaacgaag
    12001 atgaagactc ccgccctgtt cgtcacgcta tctgggctct ccgccaccgc gctggccgtg
    12061 ctcgtcctcg ctgcgatccc ggcaccggcc ggggcgatcg cccagccggc cgccccggcg
    12121 ctgccggagg agtgcgtctg ctcgcgcggg ttgcgcctcg ccgaagcgcc gccctcggtg
    12181 ctgcacaact gccagtgcgg gccgctgcag tgcgtggtgc atgcgcagtc cgggcagctg
    12241 caatgccgct gacggcgggt gatccccatg acctggcacg cttcgtcgag gcgcagcgcg
    12301 gcgtccatgc ggacgcgctg gccgagctgc gcgccgggcg caagcgcagc cactggatgt
    12361 ggttcgtctt tccgcagttg gccgggctcg gcacgagccc gaccgcgcag cgctacggcg
    12421 tccgcagcct ggacgaggcg agcgcctacc tcgcgcatcc gctgctgggt gcgcgcctgc
    12481 gtgaatgcgc gcaggccctg ctcgcgctgc gcgggcgctc ggccgagcag gtcttcggct
    12541 acccggatgt gctcaagttg cgctcctcga tgacgctctt cgccgcggtg ccgggtgcgg
    12601 atccggtgtt cggcgaggtt ctggcgcgct actacggtgg gcaggcggac gagcgcaccc
    12661 tgcacctgct tgggcagggg gccgggcgca tgcgcatccc cggcttgcct gccgggagcg
    12721 ggcatggccg cgaggagcgg gaatgacgcc gcgcatcagc gtgatcaccc tcggcgtgga
    12781 cgatctggag cgcgccgtcg ccttctaccg cgacggcctg ggctggccga cccgcggcat
    12841 cgtgggcagc gcggagcagc attcggcggt cgccttcttc gcgctgcagc cagggatcca
    12901 gctggcgctc tttccgcgtg cgagcctcgc ggtcgaggtc ggtgtggccc ggccgcgcgc
    12961 gggcacgagc gcttgcctgt tgagccacaa cgtcgcgcgg cgcgaacagg tggccgcggt
    13021 gatggcgcag gcggaggcgg cgggcgcgcg catcctgcgt gcgccgcacg acaccgcctg
    13081 gggcgggtac gcgggctact tccaggatcc ggagggccat ccgtgggagg tggcgtggaa
    13141 tccgaaatgg ccggtggagg acgattgagc ctggctgagc cccgcgtgag cgcgcgcagc
    13201 gccccgggcg gcgatctccg tgaagcgcgg aaccggacag cacgcgcctt tgtccctaaa
    13261 ctggcggctc gcaccgccgc gcgcccccgc tcctgacgcc tcacccctaa cgccttacgc
    13321 cccaatgccc tccagccgcc gcctcgtcct ctcgctcagc ctcgtcggcc tcgccgcgct
    13381 gggtgcctat gcctggtatg ccaaccgtcc gccggccgcg ctgccgggcg gggcgcagcc
    13441 ggcaggcacg caagccggcc cgtcggcggc agggacgccg ggagcgaagg cgcccgcggg
    13501 cggagcgggc ggggcgcagc cgggtccggt ggtggtggag acgcacaccg tgggcgtgcg
    13561 cgcgctcgcc gaggatatcg gcgcggtggg ctcgctggtg tcgaacgagt cggtggtgct
    13621 gcgccccgag gtgtcggggc ggatcgaggc gatccgcttc cgcgatggcg agtcggtgcg
    13681 gcgcggcgag gtgctgatcg agttcgacgc cgcggtgcaa cgggccgagc tgcagcaggc
    13741 gcgcgccagc ctcacgctgg ccgagtcgaa cttccgccgc agccaggacc tgttctcgcg
    13801 cagcttcgtg agccgcagca gcctcgacaa cgcgcgctcg cagctcgagg tggcgcgcgc
    13861 cggggtggcg ctcgcgcagg cgaagctcgc gcgcatgcag atccgcgcgc cctttgccgg
    13921 cgtggtgggc atccgcagcg tgagcccggg cgacttcgtc aaggatggtg aggccatgat
    13981 caacctcgag gacatcgcca cgctgaaggt ggacttccgc ctccccgagc tctacctgga
    14041 ccgtgtgcgc cccgggcagg ccgtggagat cgcgagcgac gtgctcgcgg gcgagcgctt
    14101 cgcggccacg gtcgaggcga tcgatccgct ggtcgatgcg cagggccgcg cgctgaggct
    14161 gcgcgcgagc ctgcccaacc ccgagctgcg cctgcgcccg ggcgtgttcg tgcgcgtgcg
    14221 cctgatcctc gccgaacgtg ccgacgtggt ggtggtgccc gaggccgcgc tggtgccggc
    14281 gccgggcaac atccagttcg tttatcgggt cgccgacggc aaggcgcagc gggtggaggt
    14341 gcggaccggc gtgcggcgcg acgcgatggt cgaggtggtc gagggcgtgc aggcgggcga
    14401 ggtggtggtc accgccggcc agctcaagct gcgcgacggc gcggcggtga aggtggcggg
    14461 cgcgcccgcc ggcgtggcgc gggcggactg agcgatggtc ctctccgagc tctgcatccg
    14521 ccgcccggtg ttcgccaccg tgctgtcgct gctcgtgctg ctggtgggcc tgatgtctta
    14581 ctcgcggctc accgtgcgcg agtatcccaa catcgacgag ccggtggtga cggtggacac
    14641 gacctaccgc ggcgccagcg ccgagatcgt cgagtcgcag gtcaccaagc cgctggagga
    14701 ttcgctcgcc ggcatcgagg gtgtggacgt gctgtcctcg atcagccgcc aggagcgcag
    14761 ccagatcacc gtgcgcttcc gtgtcgagcg cgacgccgac tcggccgcgg ccgacgtgcg
    14821 cgaccgcgtc tcgcgtgtgc gccagcgcct gcccgacgac atcgacgagc cggtgatcgc
    14881 caaggtcgag gccgacgcca gcccgatcat ctgggtggcg ttctcgtccg accggcattc
    14941 gccgatggag atcagcgact tcgccaatcg gatcatcaag ccgcgcatgc agaccctgcc
    15001 cggggcggcc gatgcgcgcc tctacggcga gcgccgccag gccatgcggg tgtggctgga
    15061 ccgcgaccgc ctcgccgcct tcgggctgac cgtgcaggac gtggaggacg ccatccggcg
    15121 ccagaacgtg gagctgcccg ccggccgcat cgagagccgc gagcgcgagt tcgccgtggt
    15181 ggcgcagacc gatctcgtcg agccggcgca attcgaggcc atcgtgctgc gccagggcga
    15241 caccgccgac gcctacccgg tgcgtatccg cgatgtcggc cgtgtcgagg tggcgcccga
    15301 gagcgagcgc accgcggtgc gcttcatggg ccggccggcg atctcgatcg gcctcatcaa
    15361 gcagtcggtg gcgaacccgc tcgacctcaa gcgcgggctc gacgagatgc tgccgcgcct
    15421 gcaggccgaa ctgcccgaag gcatgtcgat gaagatcgcc aacgacacca cggtgttcat
    15481 cgagcgctcc atcgaggcgg tgttcagcac gatctgggag gcggtgctgc tggtggccgc
    15541 ggtgtgcctg ttcttcctgc gcaactggcg ggcgatgctg gtgccgctgg tgaccatccc
    15601 ggtctcgctg gtgggcgcgt tcacgctgat gctggtgttc ggcttctcga tcaacacgct
    15661 cacgctgctg gcgctggtgc tggcgatcgg cctggtggtg gacgatgcga tcgtggtgct
    15721 ggagaacatc taccgccaca tcgaggaggg catggagccg ctggccgcgg ccttcagggg
    15781 cgcgaaggag atcggctttg cggtggtggc gatgacgatc acgctcgccg cggtgtatgc
    15841 gccggtggcc ttcatgagcg ggcgcaccgg caagctgttc accgagttcg cgctcacgct
    15901 cgccggcgcg gtgatcgtgt ccggcttcgt ggcgctgacg ctgtcgccga tgatgtgctc
    15961 gaagctgctg cgccacgagc cccggcacgg tccgatctac aacggcatcg agcgcttcct
    16021 gggctggctc acccgcggct accgcggcgt gctgggtgcg gcgctgcatg tgcgctggct
    16081 ggtgatgctg gtgttcgccg cggtggcggg gagctcggtg tggctgatgg ggcagctgaa
    16141 gaccgagctc gcgcccctgg aggaccgtgg ccgcgtgatc ggcatgttct ccggtcccga
    16201 gggcgccacg ctcgactaca tggcgcgcta tgccgaggag atcgagcgca tctacgccgg
    16261 cctgcccgag gtcgaccgct acatggtgat cgccggcaat ccgaccgtgt cgcagggcat
    16321 ctccttcgtc ggcttcaccg actgggccga acgcagccgc aaggcaggcg cgatctccgc
    16381 cgagctgcag ccgaagctgc gcgcggtgcc cggcgtcaac gccttcccca tcctgcctgc
    16441 ttcgctcggc cagagcgtgc gctcacggcc ggtgagcttc gtggtgtcga cctcagagag
    16501 ctacgacgag ctcgcccgcg tggccgaggc cttcctcgac gaaatgcgcc ggaaccccgg
    16561 cctggtgtcg cccgacacgg acctcaagct gaccatgccc gagctcgcgg tgcaggtgga
    16621 tcgcgatcgc gcggcggacc tcggcgtggc ggtggacgtg atcgggcgta cgctggagag
    16681 catgctcggc ggccgccagg tcacgcgcta caagcaggac gccgagcagt acgacgtgat
    16741 cgtgcaggtc gccgccgacg agcgccgcga cccgcgcgac atccgcgaca tctacgtgcg
    16801 cgcgcgcgac ggccgcatgg tgccgctgac cagcgtcgtg caggtggacg agcgcgtggc
    16861 gccgcgcgag ctcaaccact tcggccagcg ccgctcggtg acgatcaccg cgaacctggc
    16921 gccgggctac gcgctcggcg aggcgctggg ctggatggaa gacactgccg cccgcatcct
    16981 gccgccgggc tacggcaccg actacgacgg ccagtcgcgc gagttcaaga ccagctcgga
    17041 gagcctcgcg ctcgtcttcc tgctcgcgct cgccttcatc tatcttgtgc tggcggcgca
    17101 gttcgagagc ttccgcgacc ccttcatcat catgctgacg gtaccgctgt cgatgaccgg
    17161 cgcgctcggt gcgctgtggc tgaccggcgg tacgctcaac gtgtatagcc agatcggcct
    17221 ggtgacgctg gtggggctga tcaccaagca cggcatcctg atcgtggagt ttgccaacca
    17281 gctgcgtgag cagggtcggg cgctgcgcga ggcggtgacg gaggcagcgg tactgcgcct
    17341 gcgtccgatc ctgatgacca ccggggcgat ggtgctcggg tccgtgccgc tcgcgctggc
    17401 gaccggggcc ggcgcggaga gccgccagca gatcggctgg gtgatcgtgg gcggcctgac
    17461 catcggtacc ttcttcacgc tcttcgtggt gcctaccgtc tacaccctgc tggcacgtcg
    17521 cgagcgcgcg gcgcaggccg ggatcgtaca aggctccgcc gcctgaaata gaacgacccc
    17581 gccgcgcgag tcgcgcgggc ggggtcgatg atcgcgccgg cgcgccgatc agctttcggc
    17641 ggcgaccttc ttcaggtacg cgtagatctg gtccttgatc agcagttttt ccttcttcat
    17701 cacttcaagc tcgtggtcac tggcgggcac gatatgggtc tcgatgttgt gcaccttctc
    17761 gtcgagctcg ttgtgcttct cgaagagctg ggtgaagtgg cgatcgttgt gcttgagacg
    17821 ggtgatcagg tcgcgatatt cggggaacat gggaaaaact cctgcgttct gggttgcaag
    17881 ggctacgaac tgggataaag gaagaaaatc acgtttgtcg ccagtctact cccgcttttg
    17941 gtgtgcggcc agcgtggcgg cggcgactcg cggccggttt gcaacccgtt ccgaggaact
    18001 tgcgttcgtc attgtcggcg cttcttgggc aagcagtaaa actgatcgaa agtgcctgcg
    18061 tgcctcaacc gaacaggtga gggaagagct tcgcgcgctc ctcggcggtg agcgcctgca
    18121 tgcgcgcgat gttgcgctcg gggatgcggt cgacgtcggg gtaatgctcg atcgccttct
    18181 ccaggctctc ctcgcggatg atgtgcagca gcggccatgg cgagcgattg gtgaggttgc
    18241 ccgggtcgtc ggcctcggtg tcggcgaact ggtagtgcgg gtggaagctc gccacctgca
    18301 actcgccttc ccagccgaac tgctcgaccc acaggtccac cgcgtcgagg aagtcgttgt
    18361 agtcggcgaa gtcctcgagc atgtcgggga ttgccagcag ggtggtctcg agctccgcca
    18421 cgggtgtgtc ggacaggcgc tcgagctcgg cctggaggtc gtcgagcagg gcctcggcgg
    18481 tggtggcgtg gctgaccgcg atgcgcacgc gcttctcgcg ccgggggcgg gccgcgaagg
    18541 ggcagaggtc gaggccgatg acgacctcgt cgagccactg ctcgacgtcg gcgatgatct
    18601 gttcatccat ggagtggggt tccgttcagg cggtgtgcag ggggaggtcg tgcagcagcc
    18661 gcagcgcggt gtgcagcacg gcctcgggga ggtcggggcg caggcagtcg agctcgacga
    18721 agccgggcca ggtctcgcgg aactggcgct gccaggtgag ctgacgcttg gcgagctggc
    18781 gggtggcggc gatgcccttg aagcgcagct cgtcgtagcc ggtgccgccg tcgaggtatt
    18841 cccacacctg gcggtagccg acgcagcgca tcgagggcat ggacgggtcg agccggtagc
    18901 gcgcgcgcag ctggcggacc tcgtcgacca ggccggcgtg cagcatggcg tcgaagcgtt
    18961 cctcgatgcg cttgtgcagt acgccgcggt ccgaaggcgc gagcgcgatc ggcagcaggc
    19021 ggcagggcag gggctcgtct tccttcttcg cgtagctgtc ggcgagcgga cgcccggtga
    19081 ggcgcacgat ctcgagcgcg cgctggatgc gctgggcgtc gcccggctcg aggcgggcgg
    19141 cggcctcggg gtcgaggcgg gcgagctcgg cgtgcagcgc cggccagccg cgctcggcgg
    19201 cctcgtcgtc gagcgcgcgg cgaagttccg gatcggccgc gggcaggtcg gagagcccgt
    19261 cgcgcagcgc cttgaaatac agcatggtgc cgccggccag cagcggaaga ttgccgcgcg
    19321 cgacgatctc gcccatcagg cggatcgcgt cggcgcggaa gcgcgcggcg gagtagttct
    19381 cctcggggct gaccacgtcg atcaggtggt gcgggcacac cgcgcgctct tccgcgctcg
    19441 gcttggcggt gccgatgtcc atgtcgcggt acaccagcgc cgaatccacg ctgatcacct
    19501 ccaccggcag cgcctgcgcg agcgccagcg cgctcgcagt cttgccgctc gcagtggggc
    19561 cgagcagcag cagggcgggc ggaagagtga gggctgggga gggcgtcagg gcgggaggtg
    19621 cttctgtcgg caagagagta gggggtcgcg acggcacagg ggcgtggatt atcccccgcg
    19681 acgtcgcgat ccgccagcgc taagccgcca gcgtttcagg ctcgccgcgc gcggcggcca
    19741 attcccagcc ctgcgagacc gatggccagc aaggagaggg atacgggctc ggggaccgga
    19801 ttctgcgaga tggtgatctc gccggccagc gcctctccgt tgtcgcccac ctcgccgaga
    19861 tagagataga ggcccgatgt cgacagtgcc gagctcaggt tgaagctgat cctgccgccg
    19921 tcgccgaggc tgaggaaacc atccgcgccc gagcccgcgg tggattcgcc gtcgaacagt
    19981 ccgagggtgg cgacggcatt gtcgaccgtg ctgccggtgg ggccggtgcc gaagagcttc
    20041 ggatcggccg gatcgcgctg tactcccggc gtgaagatca caccgctcga gtagttgaac
    20101 gcgctcagcg gagagagccc tgccacacag ttggccgtgt cgcacgagtc ggacgacagg
    20161 atgatcgcgt cgaggtcgaa accactgaac cggccgggcg aaccaccgag gccggcgctg
    20221 ttgtcccgga tcgttatcga ctgcagcgta ccgatcgctg cggtcgacag atcggcacgg
    20281 aagaccgcag tcgcggcgat cgttccgccg gtggtgccgc cgagcttggt cagcgagatc
    20341 ggcgttgcgt gggcgaggcc ggctccaagg ccggccgcga ggagcgcagc ggcgatgaac
    20401 tgcttgcgga ttttcatggc tctctcctgt tcatgttttc agatggtggc cacatctcga
    20461 acggtgtgag cgttcttgtg tgcacatgaa cttgagcaag cgctatgcct gaggtccagg
    20521 cctttgattg aacgagcttt tctggcccag gaaggcgcaa tttccgatgc ggttaaaaaa
    20581 atgccgacac tttcgatggc gccgtcggac tttgcgcccc ccgcagcccg ggaggcgatc
    20641 gagccgggag cccgggcaga gcgttcgctc gcccggggct caggtgatca gcggctgccg
    20701 cgcagcatcg agcgcgtcat cgagtcgagc ggcagggcgt agtcgtgtac cgccagcacc
    20761 acgttggtct cgggctggat gaccttgagg ttcacgaaca ccagctcgct gctctgcgcg
    20821 taggtgccca ccaccaccgc ctgggcgtcg tgcgaactgg cgaggtcgcg gatctcgcgg
    20881 gtgagcatga gctccccctg gtcgcgcgcc atgtagacgt tgttgcggaa cttcatctcg
    20941 accatgcggt agccggcgag cgtgaagcgc gccgacacct gttcggagat gaggcggccg
    21001 agggtggagg actgctcgag cgcgtcgatg ttcaccacgg tggcggcaat cagcgcctgc
    21061 gccggcgcga gctggccgcg cagctgcgcg agcaggctgt cggcagcggc gtagttggag
    21121 gggatcagcg ggttggccgc agcagcgtcg aagctgactt ccttacgctg cgcgaccggc
    21181 tcggtggcgc agccggtggt gaccagcacg gtggcggaga gggctgcggc gaggattgcg
    21241 ggcgtgcgca tcattcgcct ccgacgacct ggaa
//
LOCUS       DAOTIN010000052        20949 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_3043_length_20949_cov_8.707476, whole genome shotgun sequence.
ACCESSION   DAOTIN010000052 DAOTIN010000000
VERSION     DAOTIN010000052.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 20949)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 20949)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20949
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3043_length_20949_cov_8.707476"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..321
                     /locus_tag="P5537_09435"
     CDS             <1..321
                     /locus_tag="P5537_09435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HRV78303.1"
                     /translation="AAFDGQVGQAGYASSKAGVVGLTLPVARELSRFGIRVMTIAPGI
                     METPMLMGMPQEVQDSLGKMVPFPSRLGKPAEFAALVRHIVENAYLNGEVIRLDGAIR
                     MAAK"
     gene            458..2971
                     /locus_tag="P5537_09440"
     CDS             458..2971
                     /locus_tag="P5537_09440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HRV78304.1"
                     /translation="MTPAEQPVPATAADAAADRDCYHCGLPIPPETRHYVRIDGRDRR
                     MCCVGCEAVAQSIVDNDLVDYYRHRDAMPETRREAMPVELQELGLFDHPDFQKSFVRP
                     VGEHEREAALILEGITCAACVWLNENHVARLPGVSAIEINYATRRARVRWDERQIKLS
                     DILAAIQAIGYRAYPYDAERSEQLAHRERRSMLWRVFVAGFGMMQVMMYAFPVYVAGE
                     GDMTWDIEQLLRWASLLLTLPVVLYSAAPFFQRAWRDLRLRRLGMDVPVALGVGSAFA
                     ASLWATLTDGPEVYFDSVTMFVFFLLGGRYLEMIARQKAVRGVEELGKALPSFAERIA
                     GWPGESAGERVPTSQLLAGDVLRVRPGEVIPVDGVVVEGRGEANEALLTGESMPVPKA
                     VGDRVTGGSINVSSPLLVRVEQVGDATRLAAIRRLMERAATEKPRIATLSDRVAAYFI
                     VSLLVLAAGTGVAWYLIDPARALWVFVSVLVVACPCALSLATPTALTVATDTLARMGV
                     LVTRGHAIETLARANRFVFDKTGTLTLGRMRLEEVRALGGIDAERLVVLAAAIEQGSA
                     HPVAAGLRAAAGEAVLPAVGGLLAETGQGMHGVVEGEPLWIGRPAWVASAAGLVEPAV
                     LADFAATGGTVIALAGRGGWLGLFRLADSLREDAPVITRRLAGEGVALGLLSGDAQPV
                     VDAVAARLGIRDARGGLDPQGKQQAIVDMQGDGKAVVAMVGDGVNDAPVLAQAHVSIA
                     MGGGTDLARNQADIVLLNERFASLGDGIALARRTLRIIRQNLWWSFAYNFTSVPLAMA
                     GLVTPWMAGIGMAASSLLVVLNAMRLQRAARSGRASAEN"
     gene            2973..3227
                     /gene="ccoS"
                     /locus_tag="P5537_09445"
     CDS             2973..3227
                     /gene="ccoS"
                     /locus_tag="P5537_09445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008535 - respiratory chain complex IV
                     assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cbb3-type cytochrome oxidase assembly protein
                     CcoS"
                     /protein_id="HRV78305.1"
                     /translation="MESLYLLIPLSVVLVFIIGVLFWWSLRSGQYDDLEGPAYRLLMD
                     DRDPPPGEAGEAEPSSPHGTGKEAVGDPSAGARPGETRIR"
     gene            3643..5073
                     /gene="ccoN"
                     /locus_tag="P5537_09450"
     CDS             3643..5073
                     /gene="ccoN"
                     /locus_tag="P5537_09450"
                     /EC_number="7.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004129 - cytochrome-c oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome-c oxidase, cbb3-type subunit I"
                     /protein_id="HRV78306.1"
                     /translation="MQSQATYNYKVVRQFAIMTVVWGIVGMLVGVIAAAQLVWPELNV
                     HEFLHFGRLRPLHTNAVIFAFGGSALFATSYYVVQRTCHTRLFAPGLAAFTFWGWQLV
                     IVLAAITLPLGFTSSKEYAELEWPIDILIAIVWVSYAVVFFGTIAKRKVSHIYVANWF
                     FGAFILTVALLHIVNSAAIPVSLTSMKSYSAYAGVQDAMIQWWYGHNAVGFFLTAGFL
                     GMMYYFVPKQADRPVYSYRLSVVHFWALIFTYMWAGPHHLHYTALPDWTQSVGMVFSL
                     ILLAPSWGGMINGVLTLSGAWHKLRTDPILKFLITSLSFYGMSTFEGPMMSIKTVNAL
                     SHYTDWTVGHVHSGALGWVAMISIGSVYFLLPRLYGKSEMYSVKLINAHFWIATIGIV
                     LYIASMWISGVMQGLMWRATNPDGTLTYSFVESVKASYPFWTIRFIGGAMFLSGMLIM
                     FYNMVKTIAGQKAYDAPVLSPAAAHA"
     gene            5089..5724
                     /gene="ccoO"
                     /locus_tag="P5537_09455"
     CDS             5089..5724
                     /gene="ccoO"
                     /locus_tag="P5537_09455"
                     /EC_number="7.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004129 - cytochrome-c oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome-c oxidase, cbb3-type subunit II"
                     /protein_id="HRV78307.1"
                     /translation="MAQSKHEKIERNVFLMIVLTLMTVSVGGLVEIVPLFFQHSTTSP
                     IDQKGNALDVKPYDAVRLVGRDIYIREGCNNCHSQMIRPFRAETERYGHYSVAGESVY
                     DHPFLWGSKRTGPDLARVGGRYSDEWQRVHLLNPRDVVPESNMPAFPWLDRPVKAADI
                     QDRMRALNKVGLNKYSDEEIAAAPAALEGKTELDAVVAYLQGLGTAISHFR"
     gene            5740..5928
                     /locus_tag="P5537_09460"
     CDS             5740..5928
                     /locus_tag="P5537_09460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CcoQ/FixQ family Cbb3-type cytochrome c oxidase
                     assembly chaperone"
                     /protein_id="HRV78308.1"
                     /translation="MDINDFRSLITVLGLLCFLGICAWAYSKHAKAGFDEAARLPLSD
                     DDLPAPRGRQDQEGKTNG"
     gene            5921..6811
                     /gene="ccoP"
                     /locus_tag="P5537_09465"
     CDS             5921..6811
                     /gene="ccoP"
                     /locus_tag="P5537_09465"
                     /EC_number="7.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004129 - cytochrome-c oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome-c oxidase, cbb3-type subunit III"
                     /protein_id="HRV78309.1"
                     /translation="MADFISGFWNMYVMVLVTLSILFCVFVLVSNMTKREKGEVGLHG
                     HVWDETLAEYSNPLPRWWMYLFWITIVFAVVYLAIYPGFGNSNQSRGQWAQYDAEMQA
                     AQERFGPVFAKYREMDVMAVAADPEANAMGKRLFLTYCQQCHGAAAQGAKSFPNLTDS
                     EWLWGGAPENIKETITNGRNGVMPPFGPALGADGVKDVANYVRSMNGLAHDSVRAQRG
                     KEAFEANCVACHGADAKGNPMLGAPNLTDNRWLYGSSEAVITETITLGRNNQMPAFGA
                     FLGEDKVHLLAAYVLSLSKK"
     gene            6915..8348
                     /gene="ccoG"
                     /locus_tag="P5537_09470"
     CDS             6915..8348
                     /gene="ccoG"
                     /locus_tag="P5537_09470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008535 - respiratory chain complex IV
                     assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c oxidase accessory protein CcoG"
                     /protein_id="HRV78310.1"
                     /translation="MNSASPEPQKAAKTSNPESSQDTLYASRKKLYVRSVTGLFANWR
                     WALVWITQIVFYGLPWLSWNDRQAVLLHLTERKFYIFGWVFWPQDVFFLAILLIISAY
                     ALFFFTAIAGRLWCGYACPQTVYTEIFMWIEEKIEGDHTRRQKLDRAPMSAGKAMRRG
                     AKFLVWGIVALWTGFTFVAYFSPLDELLASFNGLTFGPWETFWILFYGGFTYLFAGVL
                     REQVCKYMCPYARFQAVMFDPDTLVITYDEARGEPRGTRKKGVDPRSVSKGDCIDCGI
                     CVQVCPTGIDIRDGLQYECIGCAACIDACDQVMDKMNYPRGLIRYSTENAMKRNWGSK
                     EILAHVFRPRTLIYGTVLALISIAFVWGLAAREPLRVDVLRDRSSLGQEIEGGLIENV
                     YQLQVMNMTESARTFNIGVSGLNGIRIQGPQRVEVAPAAAQSVTVQVHVPYDEGKPGA
                     NTIFFDIAAEDDPSLTLKEETTFLVPR"
     gene            8350..8859
                     /locus_tag="P5537_09475"
     CDS             8350..8859
                     /locus_tag="P5537_09475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FixH family protein"
                     /protein_id="HRV78311.1"
                     /translation="MRSKKPEAPVEPWYRQGWPWFLIALPATAVVAGIATLVIAAKTF
                     DGMVVDDYYKEGRAIVQTIGRVEHARELGLRAALSIRSEAIHVELTATEPGSLPSSIR
                     LTVAHPTRGGLDQELVVEGRSGVYEAALAPLSTGRWLFVIEDEARSWRMDGSAYLPAE
                     MEIRIDPNV"
     gene            8884..9030
                     /locus_tag="P5537_09480"
     CDS             8884..9030
                     /locus_tag="P5537_09480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3149 domain-containing protein"
                     /protein_id="HRV78312.1"
                     /translation="MAWELLFTSDIGLLSLFTIVFILVMGAYLYRFARRHMAEDEQKA
                     RTTR"
     gene            complement(9130..9573)
                     /locus_tag="P5537_09485"
     CDS             complement(9130..9573)
                     /locus_tag="P5537_09485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HRV78313.1"
                     /translation="MFKHILVPTDGSALSDSTVARAVSFAKESGARITFFYSQPDFPM
                     PIYGEGALIDPTTPEQFAKSAASEAEAILGKARSAAEAAGVACDSDTAVNEVPYEAII
                     DAADRHGCDLIFMASHGRRGIAGLLLGSETQKVLTHSKTPVLVYR"
     gene            9708..11117
                     /locus_tag="P5537_09490"
     CDS             9708..11117
                     /locus_tag="P5537_09490"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HRV78314.1"
                     /translation="MKLTFLGAAGEVTGSCLRVDHEHGTFLVDCGLFQGGREADRKNR
                     SALDFELRGIDFVLVTHAHLDHSGLLPRLVALGYRGRIFATTATVDLLGVMLMDSAHI
                     QEKEAEWALRDTRSRKAARRAEVAPLYTVEQARTSLGRLAAADYDEWIEPGAGVRCRF
                     RDAGHILGSAIIEIEVGERGHTRRLVASGDIGQPMRPVLRDPVRIARADYLCVESTYG
                     NRAHRSFAATCDELALALRRTLEVDGGNVIIPAFAVGRTQEVLFVLADLVRGGRIGRL
                     DVVVDSPMASAVTALTVRHADLWDDETRALYAWVEANPARFRVRFVQDVEESMALNAV
                     KGGLVVISASGMCDAGRIKHHLRYNLGRRECAVVIAGFQAAGTLGRRLVDGARQVTLF
                     GERIPVRARIHTIGGLSAHADQPALLDWLRGFGEPPRRTFVVHGESAASAAFVEAVER
                     ELGWSGVEAAQPGVPVVLK"
     gene            complement(11156..11839)
                     /locus_tag="P5537_09495"
     CDS             complement(11156..11839)
                     /locus_tag="P5537_09495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HRV78315.1"
                     /translation="MPNTSPLDIPALLRRIPLFSELSEEDIQRVTRYTRERQVARGEV
                     LFQRGDLPHGFYFVVSGQVKLAFSSSQGTEKVVEIVGPMQSFGEAVMFMNHPYPVFAE
                     ALSETVLVHVGQAVVSELIDQDSTFARKLLAGMAIRLHGLIQDVETYSLRSSTQRVIG
                     YLLQVADNDAPCEIALPTSKQVIASRLNLTPETLSRIFHDLSDAGLITVQGKRVRLHD
                     PVRLSRYNA"
     gene            11922..12302
                     /locus_tag="P5537_09500"
     CDS             11922..12302
                     /locus_tag="P5537_09500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SirB2 family protein"
                     /protein_id="HRV78316.1"
                     /translation="MYYLIKNLHVTCVVLSAAGFLLRGTWMLTGSALLQHRLTRILPH
                     LVDSTLLLSAIALAVMIQQYPFSAGWVTAKVFGLLAYILLGTVALKRGRTRGMRLAAF
                     FSAILVYAWIVSVALSKDVAGYLA"
     gene            complement(12338..13078)
                     /gene="fnr"
                     /locus_tag="P5537_09505"
     CDS             complement(12338..13078)
                     /gene="fnr"
                     /locus_tag="P5537_09505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate/nitrate reduction transcriptional
                     regulator Fnr"
                     /protein_id="HRV78317.1"
                     /translation="MRASVPITVDGLKSACSQCNLVELCLPFGMSDRELSRLDELVGA
                     RRKVKRQHNLYRAGDPFEAIYAIRAGSFKTDVLLEDGREQVTGFQMTGEILGLDGIST
                     ESHSCNAVALEDSEVCVIAYEKLEQMSHEIEGLQLQFHKVMSREIVRDHGVMMLLGSM
                     RAEERLAAFLLNMSQRFTARGFSPSEFNLRMTREEIGSYLGLKLETVSRAFSRFQEDG
                     LISVQQKHVHLLDPAGLKRLIQHQHGAR"
     gene            13219..14610
                     /gene="hemN"
                     /locus_tag="P5537_09510"
     CDS             13219..14610
                     /gene="hemN"
                     /locus_tag="P5537_09510"
                     /EC_number="1.3.98.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HRV78318.1"
                     /translation="MKSQTDLIFDPQLIRKFDINGPRYTSYPTADRFVEAFNAEALRA
                     WLAKRAVGGVSKPLSLYFHIPFCNTICYYCACNKIITKDHGRSAKYLKYLAKEIAMQA
                     ACLEGSRQVTQLHLGGGTPTFLSHDEMRELMAAVREHFTLVPNGEYSIEVDPRKVDFD
                     TVKLLAELGFNRMSVGVQDFAEDVQQAVNRIQSFDETKLVIDAARANGFKSVSMDLIY
                     GLPRQNPTSFDRTLDQVLEISPDRISLYSYAHLPGLFKPQRRINSGDMPTADTKLQLL
                     QLGIRRLTEAGYVYIGMDHFAKPDDELTIAQRQGRLHRNFQGYSTHAECDLLAFGVSA
                     IGKIGPVYAQNVKTLDEYYDALDRDELPVLRGIELTADDLLRRAIIQALMCHFELSMQ
                     SIEIAYLINFREYFAEELADLQDMEKAGLVKIDGDWISVQPGGRLLVRGIAMVFDRYL
                     RADRERQRYSRVI"
     gene            14680..15390
                     /locus_tag="P5537_09515"
     CDS             14680..15390
                     /locus_tag="P5537_09515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HRV78319.1"
                     /translation="MPETGYLAVFLIGLLGGTHCVSMCGGIVGALSMQVQAPGSRPQW
                     PLHLAYNLGRIATYTLLGAGVGLLGSVGLLYEGMLPVQMTLYVLANLMLVALGLYLTG
                     FTRLLAPIERVGHVLWRRIQPATRRFLPARSVRQALPLGMLWGFIPCGLTYSILATAL
                     VTGSGARGAGLMLAFGLGTLPNLLLAGMLFKRFRDITRHPKVRLASGLLVLGFGVFGL
                     YHAPSLGGDLWRGVVCVT"
     gene            15436..15645
                     /locus_tag="P5537_09520"
     CDS             15436..15645
                     /locus_tag="P5537_09520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HRV78320.1"
                     /translation="MNETTIKVEGMSCGGCVKNVTGVLKALPGVEDVQVSLEGAAATV
                     RHDPAKVSVEALRAAVEGAGFDSPA"
     gene            15735..16262
                     /gene="ppa"
                     /locus_tag="P5537_09525"
     CDS             15735..16262
                     /gene="ppa"
                     /locus_tag="P5537_09525"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004749952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006796 - phosphate-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic diphosphatase"
                     /protein_id="HRV78321.1"
                     /translation="MGFEQVSAGKDVPNDINVIIEISAQGDPIKFEVDKDSGAVFVDR
                     FMGTSMRYPLNYGYVPHTIAGDGDPVDVLVVTPFPLQPGVVIRCRPVGVLKMEDDGGV
                     DAKVVAVPVSKLTPLYDKVQTTDDLPELLMKQTVHFFEHYKDLEPGKWVKVLGWGTVE
                     DAKAEIVNGLAAAKK"
     gene            16597..17580
                     /locus_tag="P5537_09530"
     CDS             16597..17580
                     /locus_tag="P5537_09530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bile acid:sodium symporter"
                     /protein_id="HRV78322.1"
                     /translation="MLALLMKINKNLILAIPVAMVLGFGFGLVAPVGWLKSLIVPLTF
                     LMVYPMMVNLKLSKVLEGGDLKAQALAQAINFALIPFVAYALGKAFFPDQPAYALGLL
                     LAALLPTSGMTISWTGFARGNLGAAVKMTVLGLILGSLATPLYVRWLMGAEVPVDMGA
                     VFMQIVIIVFLPMLAGHYTQKWLVARHGQAAYMKEWGPRFPPFSTLGVLGIVFVALAL
                     KAKDLVAQPGELIVVLVPLLCLYAINYVVSTVVARSLLPRGDAIALVYGTVMRNLSIA
                     LALAMNVFGASSSGAALVIALAYILQVQSAAWYVKLTDRVFGPAAPARTEG"
     gene            complement(17676..19094)
                     /gene="pyk"
                     /locus_tag="P5537_09535"
     CDS             complement(17676..19094)
                     /gene="pyk"
                     /locus_tag="P5537_09535"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HRV78323.1"
                     /translation="MKRERSARILATLGPASSTRERIRALAEAGADVFRLNFSHGSHE
                     DHAERYRLIRAVEAELGRPIGVLMDLQGPKLRVGRFAEGKVALVPGASFRLDLDPTPG
                     DARRANLPHPEIFAALEAGTALLLDDGKLRLRVDACGADFAETTVLVGGTLSDRKGVN
                     VPGVVLPISPLTAKDRADLDFGLALGVDWVALSFVQRPEDLREARELVGDRAWIMAKL
                     EKPAAIDALEPIVALADGVMVARGDLGVELPPQQVPVLQRRIVRAARAAGRPVVVATQ
                     MLESMISSPVPTRAEASDVATAIYDGADAVMLSAESASGQYPVEAVSIMHGIVCEVER
                     DPAWRAGLEASHTPAAANTPDAICCALRRVAGLLEPAATVAYTSSGFSALRASRERPV
                     APILALTPQPATARRLALVWGVHPVPFEEVHDVAEMVEHAARAALTLGFGRAGDAVVV
                     IAGLPFGQRGSTNLLHVARIPD"
     gene            complement(19112..19531)
                     /locus_tag="P5537_09540"
     CDS             complement(19112..19531)
                     /locus_tag="P5537_09540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HRV78324.1"
                     /translation="MIPTHALTLADARVAAAAAEAEARANGWAVSIAICDAGGHALWL
                     QRMDGAPLMSAIVAPEKARTCVLSGKPSKAFEDMVNNGRFAALAMPVVPLEGGEPVVV
                     DGRVVGAVGVSGVKAGEDARVARAGVDALLACAHTPA"
     gene            complement(19581..20003)
                     /locus_tag="P5537_09545"
     CDS             complement(19581..20003)
                     /locus_tag="P5537_09545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3830 family protein"
                     /protein_id="HRV78325.1"
                     /translation="MRHLAIDVGSFRFVARMEEVAAPRTCAAFLELLPFSNQVIHSRW
                     SGEAVWVPLGEFDTGLGFENHTSHPSRGDLLLYPGGFSETEILFAYGSSCFASKMGQL
                     AGNHFLTVVEGAEQLHEMGRTVLWKGAQWIRFTDLGER"
     gene            complement(20014..20898)
                     /locus_tag="P5537_09550"
     CDS             complement(20014..20898)
                     /locus_tag="P5537_09550"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014085688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008679 - 2-hydroxy-3-oxopropionate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0019580 - galactarate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HRV78326.1"
                     /translation="MANIGFIGLGIMGTPMAGNLIKGGHTVFTHTRGETPAVLREAGA
                     QPCASGAEVARQADIVITMVPDTPHVEDVLFKPDGVAAGLSKGKVVVDMSSISPVATK
                     DFARRINALGCEYLDAPVSGGEVGAKAATLTIMVGGSEAAFDMVKPIFELMGKNITLV
                     GGNGDGQITKVANQIIVALNIEAVGEALLLAAKAGADPAKVRQALMGGFANSRILEVH
                     GERMVKRTFDPGFRIELHQKDLNLALTTARQLGVSLPNTATAQELFNACSAHGGAKWD
                     HSGMVRALEKMANFEIGQ"
BASE COUNT         3217 a         7048 c         7108 g         3576 t
ORIGIN      
        1 gccgccttcg acggccaggt cggccaggcc ggctacgcct cgtcgaaggc cggcgtggtc
       61 gggctgaccc tgccggtggc gcgcgagctg tcccgcttcg gcatccgcgt gatgaccatc
      121 gcccccggca tcatggagac gccgatgctg atgggcatgc cgcaggaggt gcaggactcg
      181 ctcggcaaga tggttccctt cccctcgcgc ctcggcaagc ctgccgagtt tgccgcgctg
      241 gtgcgccaca tcgtcgagaa cgcctacctg aacggcgagg tgatccgcct cgatggcgcg
      301 atccgcatgg ccgccaagta gagccctgtg cgccgcagcg gccgcccgcc ggcgatgctg
      361 cggtgcaatg gccggggccg gtgaattgtg ttattaaacc ggttccaatt cttcccgccc
      421 cgcgcgtgtg cgtgcggggc ggtttcgctt ggcgccgatg acccctgccg aacagcctgt
      481 tcccgcgacc gcagccgatg ccgctgcgga tcgcgactgc tatcactgcg gcctgccgat
      541 cccgcccgag acccggcact acgtacgcat cgacggccgt gatcggcgca tgtgctgcgt
      601 tggctgcgag gcggtggcgc agtccatcgt cgacaacgac ctggtcgatt actaccgcca
      661 tcgcgacgcg atgcccgaga cgcgccgcga ggcgatgccg gtcgagctgc aggagctcgg
      721 tctcttcgat catcccgact tccagaagag cttcgtgcgc ccggtgggcg agcacgagcg
      781 cgaggccgcg ctgatcctcg agggcatcac ctgcgccgca tgcgtgtggc tcaacgagaa
      841 ccacgtcgcc cgcctgcccg gcgtgtcggc gatcgagatc aactacgcta cccggcgtgc
      901 gcgcgtgcgc tgggacgagc gccagatcaa gctctccgac atcctcgccg ccatccaggc
      961 gatcggctac cgcgcctatc cctacgacgc cgagcgctcc gagcagctcg cccaccgcga
     1021 gcggcgctcg atgctgtggc gggtgttcgt cgccggcttc ggcatgatgc aggtgatgat
     1081 gtacgccttc ccggtctacg tggccggaga gggcgacatg acctgggaca tcgagcagct
     1141 gctacgctgg gccagcctgc tgctgaccct gcccgtggtg ctgtactcgg ctgcgccctt
     1201 cttccagcgc gcctggcgcg acctgcgcct gcgccggctt ggcatggacg tgccggtcgc
     1261 gctcggcgtg ggcagcgcct tcgccgccag cctgtgggcg acactgaccg acgggccgga
     1321 ggtgtacttc gactcggtca cgatgttcgt gttcttcctg ctcggcgggc gctacctcga
     1381 gatgatcgcg cgccagaagg cggtgcgggg ggtcgaggaa ctgggcaagg cgctgccctc
     1441 gttcgccgag cgcatcgcgg gctggccggg agaatccgcc ggcgagcgcg tgccgacctc
     1501 gcagctgctg gcgggggacg tgctgcgggt tcgtccgggc gaggtgatcc cggtcgacgg
     1561 cgtggtggtc gaggggcgcg gcgaggccaa cgaggcgctg ctcaccggcg agagcatgcc
     1621 ggtgcccaag gcggtcggtg atcgcgtcac cggcggcagc atcaacgtgt cctcgccctt
     1681 gctggtccgc gtcgagcagg tcggcgacgc cacccggctg gcggcgatcc ggcgcctgat
     1741 ggagcgcgcg gcgaccgaga agccgcgcat cgcgacgctg tcggaccgcg ttgccgccta
     1801 cttcatcgtc agcctgctgg tgctggctgc ggggacgggg gtggcctggt atctgatcga
     1861 ccccgcgcgc gcgctttggg tcttcgtgtc ggtgctggtg gtcgcctgcc cgtgcgcgct
     1921 ctcgctcgct accccgaccg cgctcaccgt ggccaccgat accctggcac ggatgggcgt
     1981 gctggtcacg cgcgggcatg cgatcgagac gctggcgcgg gccaatcgtt tcgtcttcga
     2041 caagacgggc acgctgaccc tgggcaggat gcggttggag gaggtgcgtg cgcttggcgg
     2101 catcgacgcg gagcgcctgg tggtgctggc cgcggcgatc gagcagggct cggcgcaccc
     2161 ggtcgcggcc ggcctgcgcg cggcggcggg cgaggccgtc ttgccggcgg tgggcggcct
     2221 gctcgccgag accgggcagg gcatgcatgg cgtggtcgag ggcgagccgc tgtggatcgg
     2281 ccgcccggcc tgggtggcga gcgccgccgg tcttgtggaa cctgccgtgc ttgcggattt
     2341 cgcggccacg gggggcaccg tgatcgcgct cgccgggcgg ggcggctggc tgggcctgtt
     2401 ccgcctcgcc gacagcctgc gcgaggatgc gccggtgatc actcgccgcc ttgcgggcga
     2461 gggcgtcgcg ctcggcctgc tctcgggtga cgcgcagccg gtggtcgatg cggttgccgc
     2521 ccggctgggc atccgggacg cgcgcggcgg cctggacccg cagggcaagc agcaggcgat
     2581 cgtcgacatg caaggcgacg gcaaggccgt ggtagcgatg gtgggcgacg gcgtgaacga
     2641 cgcgccggtg ctcgctcagg cccatgtctc gatcgcgatg ggcggcggca ccgacctcgc
     2701 ccgcaaccag gccgacatcg tgctgctcaa cgagcgcttc gccagcctgg gcgacggcat
     2761 cgcgctggcc cgccggaccc tgcgcatcat ccggcagaac ctgtggtggt cgttcgccta
     2821 caatttcacc tcggtgccac tcgcgatggc cgggctggtg acgccgtgga tggccggcat
     2881 cggcatggcg gcgagttcgc tgctcgtcgt gctcaacgcc atgcggctgc agcgcgccgc
     2941 acggagcggt cgcgcaagcg cggagaattg agatggaaag cctctacctg ctgattccgc
     3001 tgtcggtggt gctggtcttc atcatcggtg tgctgttctg gtggtcgctg cgcagcggcc
     3061 agtacgacga cctcgaggga cccgcctacc ggctgctgat ggacgaccgc gacccgccgc
     3121 ccggggaggc cggcgaggcg gagccgagtt cgccacacgg gaccggaaaa gaggcggtcg
     3181 gagacccctc cgcgggcgcc aggccgggtg aaacgaggat tcgttgacct acgtcaacgt
     3241 ctgtccgatg gttaagagga aaatgacgcc gttgcgatcg atcgccgagc atgacgatgg
     3301 cgagcgatcc gtggtttatg tctctctgtt ggggttgggg gtgcgtgaag acgcaccctt
     3361 ttttttgcct gtcgccaggt gccccaaaaa cgctggaacc cgcgcagatg ctggattccc
     3421 gcgtgcccga acgatttctc gcggtatccg cagcgggcgc ctgcatttgt ttttggacta
     3481 actccaattt ccccttcctt ggccccgtct gctgcaatac aatattgact tgtgtcaaat
     3541 tgcgtatgtg gtcgtggcgt attctcgccc gggtgggtcg ccgcgctggt ctggtgcggc
     3601 ccgacgcaag caggggtttt caaaaacaaa gaggtgatcc agatgcaatc gcaagcgact
     3661 tataactata aagtcgtgcg ccagttcgcc atcatgacgg tggtgtgggg catcgtgggc
     3721 atgctggtcg gcgtgatcgc cgcagcacag ctcgtgtggc ccgaactgaa cgtgcacgag
     3781 ttcctgcatt tcggcaggct tcgtccgctg cacaccaacg cggtcatctt cgcgttcggt
     3841 ggctcggcgc tgttcgcgac gtcgtactac gtcgtccagc gcacctgtca caccagactg
     3901 ttcgcgcccg gactggccgc gttcaccttc tggggatggc aactggttat cgtgctggcc
     3961 gcgatcaccc tgccgctggg cttcacctcc tccaaggaat acgccgaact cgagtggccg
     4021 atcgacatcc tgatcgcgat cgtctgggtg tcctacgccg tcgtgttctt cggcaccatc
     4081 gccaagcgca aggtctcgca catctacgtc gcgaactggt tcttcggcgc cttcatcctc
     4141 accgtcgcgc tgctgcacat cgtcaatagc gccgcgatcc cggtctcgct caccagcatg
     4201 aagtcgtatt cggcctacgc cggcgtgcag gacgcgatga tccagtggtg gtacggccac
     4261 aacgcggtcg gcttcttcct gaccgcgggc ttcctcggca tgatgtacta cttcgtgccc
     4321 aagcaggccg accgtccggt ctactcctac cgcctgtcgg tggtgcactt ctgggcgctg
     4381 atcttcacct acatgtgggc gggcccgcac cacctgcact acaccgcgct gcccgactgg
     4441 acccaatcgg tgggcatggt gttctcgctg atcctgctgg cgccgtcctg gggtggcatg
     4501 atcaacggcg tgctgaccct gtcgggcgcc tggcacaagc tgcgcaccga cccgatcctg
     4561 aagttcctca tcacctcgct gtccttctac ggcatgtcga ccttcgaagg cccgatgatg
     4621 tcgatcaaga cggtcaacgc tctgtcgcac tacaccgact ggacggtcgg ccacgtgcac
     4681 tcgggcgcgc tcggctgggt ggcgatgatc tccatcggct cggtgtactt cctgctgccg
     4741 cgcctctacg gcaagagcga gatgtacagc gtcaagctga tcaacgccca cttctggatc
     4801 gccaccatcg gcatcgtgct ctacatcgcc tcgatgtgga tctcgggcgt gatgcagggc
     4861 ctgatgtggc gcgccaccaa cccggacggc acgctcacct actccttcgt cgaatcggtc
     4921 aaggccagct atccgttctg gacgatccgc ttcatcggcg gcgcgatgtt cctcagcggc
     4981 atgctgatca tgttctacaa catggtgaag acgatcgccg gccagaaggc ctatgacgcc
     5041 ccggtgctgt cgcccgcggc tgcccacgcc tgatcggaga acaacaacat ggctcaatcg
     5101 aaacacgaaa agatcgaacg caacgtattc ctcatgatcg tgctcacgct gatgaccgtc
     5161 agcgtggggg gtctggtgga gatcgtgccg ctgttcttcc agcactcgac cacctcgccg
     5221 atcgaccaga agggcaacgc gctcgacgtc aagccgtacg atgcggttcg cctggtgggg
     5281 cgcgacatct acatccgcga aggctgcaac aactgccact cgcagatgat ccgtccgttc
     5341 cgtgccgaga ccgagcgcta tggccactac tcggtggcgg gcgagtcggt gtacgaccac
     5401 cccttcctgt ggggatcgaa gcgtaccggt ccggacctcg cccgcgtcgg tggccgctac
     5461 tccgacgagt ggcagcgggt gcatctgctg aacccgcgcg acgtcgtccc cgagtcgaac
     5521 atgccggcct tcccctggct tgaccgcccg gtcaaggcgg cggacatcca ggaccgcatg
     5581 cgcgcgctca acaaggtcgg cctgaacaag tacagcgacg aagagatcgc cgccgcgccg
     5641 gctgcgctcg agggcaagac cgagctcgat gccgtcgtgg cctatctgca gggcctgggc
     5701 accgcgattt cgcacttcag ataaggaagc aaacgcgccg tggatatcaa cgatttccgt
     5761 agcctgatca ccgtgctggg gctgctgtgc ttcctgggca tctgcgcctg ggcatacagc
     5821 aagcacgcca aggccgggtt cgacgaggcg gcgcgtctgc ccctgagcga cgacgacctg
     5881 ccggccccgc gcggccggca agaccaagag ggaaaaacaa atggctgact tcatcagcgg
     5941 tttctggaac atgtatgtga tggtcctcgt gaccctctcc atcctgttct gtgtgttcgt
     6001 gctcgtgtcg aacatgacca agcgcgagaa aggggaggtc ggactgcacg ggcacgtgtg
     6061 ggacgagacg ctcgccgagt acagcaaccc gctgccgcgc tggtggatgt acctgttctg
     6121 gatcaccatc gtgttcgcgg tggtctatct ggcgatctat ccgggcttcg gcaacagtaa
     6181 ccagagccgc ggccagtggg cgcagtacga cgccgagatg caggcggcgc aggagcgctt
     6241 cggtccggtg ttcgccaagt atcgcgagat ggacgtgatg gcggtcgccg ccgatcccga
     6301 ggccaacgcg atgggcaagc gcctgttcct gacctactgc cagcagtgcc acggcgctgc
     6361 ggcgcagggc gcgaagagct tccccaacct gaccgacagc gagtggctgt ggggtggggc
     6421 gccggagaac atcaaggaga ccatcaccaa cggccgtaac ggcgtgatgc ctccgttcgg
     6481 tcccgcgctc ggcgccgatg gcgtcaagga cgtcgccaac tacgtgcgtt cgatgaacgg
     6541 cctcgcgcac gactcggtgc gtgcgcagcg cggcaaggaa gccttcgagg ccaactgcgt
     6601 ggcctgccac ggcgcggacg ccaagggcaa cccgatgctc ggcgcgccca acctgaccga
     6661 caaccgctgg ctgtacggct cgtccgaggc ggtgatcacc gagaccatca ccctcgggcg
     6721 caataaccag atgccggcct tcggtgcctt cctcggcgag gacaaggtgc atctgctcgc
     6781 cgcctacgtg ctgagcctga gcaagaagta agcgtcaccc gcagtacctg cagcaagcat
     6841 cgcatccccg ggaggagggg ccctcccggg gttctcgata acaacaagaa caagaattca
     6901 tcggtaccaa ggccatgaac agcgcatccc ccgagccgca gaaggcggcc aagacgtcca
     6961 accccgagtc ctcccaggac accctctacg cctcccgcaa gaagctctac gtccgctccg
     7021 tgaccgggct gttcgccaac tggcgatggg cgctggtgtg gatcacccag atcgtcttct
     7081 acggtctgcc ctggctgagc tggaacgacc gccaggcggt gctgctccac ctcaccgaac
     7141 gcaagttcta catcttcggc tgggtgttct ggccgcagga cgtgttcttc ctcgcgatcc
     7201 tgctgatcat ctccgcctac gcgctgttct tcttcaccgc gatcgccggc cgcctgtggt
     7261 gcggctacgc ctgtccgcag acggtctaca ccgagatctt catgtggatc gaggagaaga
     7321 tcgagggcga ccatacccgt cgccagaagc tcgaccgcgc gccgatgagc gccggcaagg
     7381 ccatgcgccg cggcgccaag ttcctcgtgt ggggcatcgt cgcgctgtgg accggcttca
     7441 ccttcgtcgc ctacttctcg ccgctcgacg agctcctcgc ctccttcaac ggcctcacct
     7501 tcgggccctg ggagaccttc tggatcctct tctacggcgg cttcacctac ctgttcgccg
     7561 gcgtgctgcg cgagcaggtg tgcaagtaca tgtgcccgta cgcccgcttc caggcggtga
     7621 tgttcgatcc cgacaccctg gtcatcacct acgacgaggc ccgcggcgag ccgcgcggca
     7681 cgcgcaagaa gggcgtcgat ccgcgctccg tgtccaaggg cgactgcatc gactgcggca
     7741 tctgcgtcca ggtgtgcccg accggcatcg acatccgcga cggcctgcag tacgagtgca
     7801 tcggctgcgc cgcctgcatc gacgcctgcg accaggtcat ggacaagatg aactacccgc
     7861 gcggcctcat ccgttactcg accgagaacg cgatgaagcg gaactggggc tcgaaggaga
     7921 tcctcgcgca tgtgttccgt ccgcgcacgc tgatctacgg caccgtcctc gccctcatca
     7981 gcattgcgtt tgtgtggggg ctggctgcgc gcgagccgct gcgggtcgac gtcctgcgcg
     8041 accgctcctc gctcggacag gagatcgagg gcggactgat cgagaacgtc taccagctcc
     8101 aggtcatgaa catgaccgag tccgcgcgca cgttcaacat cggcgtgtcg gggctgaacg
     8161 gcatccgcat ccagggaccg cagcgagtcg aggtggcacc ggccgcggcg cagtcggtta
     8221 ccgtgcaggt gcacgtgccc tacgacgagg gcaagccggg tgccaacacg atcttcttcg
     8281 acattgccgc ggaagacgac ccctccttga cgctcaagga agagaccact ttcctggtgc
     8341 cgcgctgaca tgcgaagcaa gaaacccgaa gccccggtcg agccctggta ccgccagggc
     8401 tggccctggt tcctgatcgc gctgccggcg accgccgtgg tcgccggcat cgcgaccctg
     8461 gtgatcgccg cgaagacctt cgacggcatg gtggtcgacg actactacaa ggaaggccgt
     8521 gcgatcgtgc agacgatcgg ccgcgtcgag cacgcccgcg agctcggcct acgcgccgcg
     8581 ctgagcatcc gcagcgaggc gatccacgtg gagctgaccg ccaccgagcc gggcagcctg
     8641 ccgtcgagca tccgcctcac cgtcgcccac ccgacgcgcg gcggcctgga tcaggagctc
     8701 gtcgtcgaag ggcgctcggg tgtatatgag gccgcgctcg ctccgctgag caccggccgc
     8761 tggttgttcg tcatagaaga tgaggcccga agctggagaa tggacgggtc cgcttacctc
     8821 cctgcagaga tggagatccg gatcgatccg aatgtctgat tttcttgcaa agggagaagc
     8881 accatggcct gggagttgtt gttcacgagc gatatcggtc tgctgagcct gttcaccatc
     8941 gtcttcattc tggtgatggg cgcctacctg taccgcttcg cccgccgcca catggcggag
     9001 gacgagcaga aggcccgcac gacgcgctga ccggcaaccc gccgacgagc gatccgcacg
     9061 acggatgaaa gacggcccgc aagcgggccg tttgtacttg aagccgccct tgccgggctg
     9121 cgaccggttt cagcgataga ccagcaccgg cgtcttgctg tgggtcagca ccttctgcgt
     9181 ctcggagccg agcagcaggc cggcgatgcc gcggcggccg tgggaggcca tgaagatcag
     9241 gtcgcagccg tggcgatcgg cggcatcgat gatcgcctcg tagggcacct cgttcaccgc
     9301 ggtgtcgcta tcgcaggcca cgccggccgc ttcggcggcg ctgcgcgcct tgcccaggat
     9361 cgcctcggcc tcggacgccg ccgatttggc gaactgctcg ggtgtggtcg ggtcgatcag
     9421 ggcgccctcg ccgtagatcg gcatcgggaa gtcgggctgc gagtagaaga aggtgatgcg
     9481 cgcgccgctc tccttggcga aggagacggc acgggcgacc gtgctgtccg agagtgccga
     9541 gccgtcggtc ggtaccagga tgtgcttgaa catgaagtac gctccctgtg gtgtgtgtgc
     9601 ttcgattata gcgggcggag agggggcgcc acgattgatc gtgatcaagc agccgcgcga
     9661 tcgcgacagg cacagtggaa atccctgaag aatccgcgag gccagtgatg aagctcacct
     9721 tcctcggtgc cgccggcgag gtcaccggct cctgcctgcg cgtcgatcac gagcacggca
     9781 cattcctggt ggattgcggc ctcttccagg gcgggcgcga ggccgatcgc aagaaccgca
     9841 gcgcgctcga cttcgagttg cgcggcatcg atttcgtgtt ggtgacccac gcccacctcg
     9901 accactccgg actgctgccg cgcctggtgg cgctgggcta ccgcgggcgg atcttcgcga
     9961 ccacggccac cgtcgacctg ctcggcgtga tgctgatgga ctccgcgcac atccaggaaa
    10021 aggaagccga gtgggcgctg cgcgacacgc gctcgcgcaa ggccgcgcgc agggcggagg
    10081 tggcgccgct ctacaccgtg gagcaggcgc gcaccagcct cggccgcctc gcagccgccg
    10141 actacgacga gtggatcgaa ccgggcgcgg gcgtgcgctg ccgctttcgc gacgccggac
    10201 acatcctcgg ctcggcgatc atcgagatcg aagtcggcga gcgcggccac acccgccggc
    10261 tggtggcctc gggggacatc ggccagccga tgcggcccgt gctgcgggat ccggtgagga
    10321 tcgcgcgcgc cgactacctg tgcgtcgagt ccacctacgg caaccgcgcc catcgctcct
    10381 tcgcggcgac ctgcgacgag ctcgccctgg cgctgcggcg cacgctggaa gtggatggcg
    10441 gcaacgtcat cattcccgcc ttcgccgtgg ggcgcaccca ggaggtgctc ttcgtgctcg
    10501 ccgacctcgt gcgcggcggg cgaatcggcc gcctcgacgt cgtggtcgac tcgccgatgg
    10561 cctccgcggt caccgcgctc accgttcgcc atgcggacct ctgggacgac gagacgcgtg
    10621 cgctctatgc ctgggtcgag gccaaccccg cgcgcttccg cgtccgcttc gtccaggacg
    10681 tggaggagtc gatggcgctc aatgcggtga agggcggcct ggtcgtgatc tcggcgagcg
    10741 gcatgtgcga tgccggccgg atcaagcacc acctgcgcta caacctcggc cggcgcgagt
    10801 gcgcggtggt gatcgcgggc ttccaggccg ccggcacgct cggccgcagg ctggtcgacg
    10861 gcgcgcgcca ggtcacgctg ttcggcgagc gcatcccggt gcgcgcgcgc atccacacca
    10921 tcggcggact gtccgcccac gccgaccagc ccgcgctgct cgactggctg cgcggcttcg
    10981 gcgagccgcc gcggcggacc ttcgtggtcc acggcgaatc tgccgcctcg gccgccttcg
    11041 tcgaggcggt cgagcgcgaa ctgggctgga gcggggtgga ggcggcacag cccggcgtgc
    11101 cggtcgtgct gaagtgagca cacgagcgga tgcgcaggcg cgcggcgcgg cgcgctcagg
    11161 cgttgtagcg cgacagccgg acggggtcgt gcaggcgcac gcgcttgccc tgcacggtga
    11221 tcaggccggc gtcgctgagg tcgtggaaga tgcgcgagag cgtctcgggc gtgaggttga
    11281 gccgcgaggc gatcacctgc ttgctggtcg gcagggcgat ctcgcagggc gcgtcgttgt
    11341 cggccacctg caggaggtag ccgatcacgc gctgggtgct cgatcgcagc gagtaggtct
    11401 cgacgtcctg gatcagcccg tgcaggcgga tcgccatgcc ggcgagcagc ttgcgcgcga
    11461 aggtggagtc ctggtcgatg agttcgctca ccaccgcctg gccgacatgc accagcacgg
    11521 tctcgctcag ggcctcggcg aagaccggat aggggtggtt catgaacatc accgcctcgc
    11581 cgaagctctg catcggtccg acgatctcga ccaccttctc cgtgccctgg gaagacgaga
    11641 aggcgagctt gacctgaccg gagaccacga agtaaaagcc gtgcggcagg tcgccgcgct
    11701 ggaacagcac ctcgccgcgg gcgacctggc gctcgcgggt atagcgcgtg acccgctgga
    11761 tgtcctcttc cgacagttcg ctgaacagcg ggatgcggcg cagcagggca gggatgtcga
    11821 gcggggacgt gttgggcatc tggaactctc cgtctggggg cgcaatttta attcagccgg
    11881 ctgccgatcg gcgcccgggc cggctttcga aaggatcgtg gatgtactac ctgatcaaga
    11941 acctgcacgt gacctgcgtc gtcctgagcg ccgccggctt cctgctgcgc ggcacctgga
    12001 tgctcaccgg cagcgccctg ctgcagcacc gcctgacccg gatcctgccg cacctcgtcg
    12061 acagcacgct gttgctgtcg gcgatcgcac tggcggtgat gatccagcaa taccccttca
    12121 gcgcgggctg ggtcaccgcc aaggtgttcg ggctgctcgc ctacatcctg ctcgggacgg
    12181 tggcgctcaa gcgcgggcgt acccgtggca tgcgcctcgc cgccttcttc tccgcgatcc
    12241 tggtgtatgc gtggatcgtt tcggtggcgc tgagcaagga cgtcgccggc tacctggcct
    12301 gagggtgcgg ctgagcccgc ctgccggccc ggcgcgctca gcgcgcgccg tgctggtgct
    12361 ggatcaggcg cttgagcccg gccggatcga gcaggtgaac gtgcttctgc tgtaccgaga
    12421 tcaagccgtc ctcctggaaa cgcgagaagg cacgagacac cgtctcgagc ttgaggccga
    12481 ggtaggagcc gatctcctcg cgcgtcatgc gcaggttgaa ctcgctaggc gagaaaccgc
    12541 gcgcggtgaa gcgctgcgac atgttgagca ggaaggcggc gaggcgctct tccgcgcgca
    12601 tcgagccgag cagcatcatc acgccatggt cgcgcacgat ctcgcggctc atgaccttgt
    12661 ggaactgcaa ctgcaggccc tcgatctcgt gcgacatctg ctcgagcttc tcgtaggcga
    12721 tcacgcagac ctcgctgtcc tcgagcgcca ccgcgttgca gctgtgggac tcggtgctga
    12781 tgccgtcgag gccgaggatc tcgcccgtca tctggaagcc ggtcacctgc tcgcggccat
    12841 cctcgagcag cacgtcggtc ttgaacgagc ccgcgcggat cgcatagatg gcctcgaacg
    12901 ggtcgccggc acggtagagg ttgtgctggc gcttcacctt gcgccgagcg cccaccaact
    12961 cgtcgagccg gctcaattcg cgatcggaca tcccgaaggg caggcacaac tcgacgaggt
    13021 tgcactgcga acaggccgac ttcagcccat ccacggtaat tggcacgcta gccctcatct
    13081 gcacgataat cctgctttcc tgacattaga gacgcctgcg ctcgagcggc gcgactgcta
    13141 atcacacccg ttgacccaag tcaaccaaca taagggaggc ttctgccatt gttctgcaga
    13201 gagcccgcca gcaagatcat gaaaagccag accgacctca tcttcgaccc gcaactgatc
    13261 cgtaaattcg acatcaacgg gccgcgctac acctcttatc ccacggcgga ccgcttcgtc
    13321 gaggccttca acgccgaagc gctgcgggcc tggctggcca agcgggccgt gggcggcgta
    13381 agcaaaccgc tctcattata cttccacatc cccttctgta acacgatctg ctattactgc
    13441 gcctgcaaca agatcattac caaggatcat ggtcggtcag ccaagtatct gaaatatctg
    13501 gcgaaagaaa ttgcgatgca ggccgcctgc ctggagggta gccgccaggt cacccagctt
    13561 cacctcggtg gcggcacgcc gaccttcctg tcgcacgacg agatgcgcga gctcatggcg
    13621 gcagtgcgcg agcacttcac cctggtgccc aacggcgaat attcgatcga ggtcgatccg
    13681 cgcaaggtcg atttcgacac cgtgaagctg ctcgccgagc tcggcttcaa ccgtatgagc
    13741 gtgggcgtgc aggacttcgc tgaggacgtg cagcaggcgg tcaaccgcat ccagagcttc
    13801 gacgagacca aactggtgat cgacgcggcg cgcgccaacg gcttcaagtc ggtgagcatg
    13861 gacctgatct acggcctgcc gcggcagaac ccgaccagct tcgaccgcac gctcgaccag
    13921 gtgctggaga tctcgcccga ccgcatctcg ctgtacagct acgctcacct gccgggcctg
    13981 ttcaagccgc agcgccgcat caacagcggc gacatgccca ccgccgatac caagctgcaa
    14041 ctgctgcagc tcggcatccg ccggctcacc gaggcgggct acgtgtatat cggcatggac
    14101 cacttcgcca agcctgacga cgagctcacc atcgcccagc gccagggccg cctgcaccgc
    14161 aacttccagg gctactccac ccacgccgag tgcgacctgc tcgccttcgg ggtgtcggcg
    14221 atcggcaaga tcggcccggt gtatgcgcag aacgtgaaga ccctcgacga gtactacgat
    14281 gcgctcgatc gcgacgagct gccggtgctg cgcggcatcg agctcaccgc cgacgacctg
    14341 ctgcggcgcg cgatcatcca ggcgctgatg tgccacttcg agctgtcgat gcagtcgatc
    14401 gagatcgcct acctgatcaa cttccgcgaa tatttcgccg aggaactcgc cgacctgcag
    14461 gatatggaga aggccggcct ggtgaagatc gacggcgact ggatcagcgt gcagccgggc
    14521 ggtcgtctgc tggtgcgcgg tatcgcgatg gtcttcgatc gctacctgcg cgccgaccgc
    14581 gagcgccagc gctactcgcg ggtgatctga acgccgcacg gattgcgcac cgcagcgtag
    14641 aataaaggcc tcgcattttc cgcggggcct ttctccttca tgcccgaaac cggatacctc
    14701 gccgtcttcc tgatcggcct gctcggcggc acgcactgcg tgtcgatgtg cggcggcatc
    14761 gtcggcgcgc tcagcatgca ggttcaggcg ccgggcagcc ggccgcagtg gccgctgcac
    14821 ctggcctaca acctcgggcg catcgccact tacaccctgc tcggcgccgg cgtgggcctg
    14881 ctcggctcgg tcggcctgct ctacgagggc atgctgccgg tgcagatgac gctctacgtg
    14941 ctcgccaacc tgatgctggt ggcgctcggg ctctacctca ccggcttcac ccgcctgctc
    15001 gcgcccatcg agcgcgtcgg ccacgtgctg tggcggcgca tccagccggc cacgcggcgc
    15061 ttcctgcccg cgcgctcggt tcgccaggcg ctgccgctcg gcatgctgtg gggcttcatc
    15121 ccttgcgggc tcacctattc catcctcgcc accgcgctgg tcaccgggtc gggcgcgcgc
    15181 ggcgccgggc tgatgctggc cttcgggctg ggcacgctgc ccaacctgct gcttgccggc
    15241 atgctgttca agcgtttccg cgacatcacc cgccacccca aggtgcgcct ggcctccggc
    15301 ctgctggtgc tcggcttcgg cgtgttcggg ctgtaccacg cgccctcgct cggcggcgac
    15361 ctgtggcgcg gcgtggtgtg cgtgacctga gggcgcggcg gcgccccctt tcaatccatc
    15421 aggagtagag attcgatgaa cgagacgacg atcaaggtcg aaggcatgag ctgcggcggc
    15481 tgcgtgaaga acgtcaccgg cgtgctgaag gcgctgccgg gcgtggagga tgtgcaggtg
    15541 tcgcttgaag gcgccgccgc cacggtgcgt cacgaccccg ccaaggtttc ggtcgaggcg
    15601 ctgcgcgccg cggtcgaggg cgcgggcttc gattccccgg cctgatccgc cgcccccacc
    15661 ggggcattcc cgcagtgcaa gacattgtgg tttcccccta taatccgcgc acaatttttc
    15721 cacgggaggg atgtatgggt ttcgaacagg tcagcgccgg caaggacgtg ccgaacgaca
    15781 tcaacgtcat catcgagatc tccgcccagg gcgatccgat caagttcgag gtggacaagg
    15841 acagcggcgc cgtcttcgtc gaccgcttca tgggcacctc gatgcgctac ccgctgaact
    15901 acggctacgt tccgcacacc atcgccggcg acggcgatcc ggtcgacgtg ctggtcgtga
    15961 ccccgttccc gctgcagccg ggcgtggtca tccgctgccg cccggtcggc gtgctcaaga
    16021 tggaagacga cggcggcgtc gacgccaagg tcgtggccgt gccggtttcc aagctgaccc
    16081 cgctgtacga caaggtgcag accaccgacg acctgcccga gctgctgatg aagcagacgg
    16141 tgcacttctt cgagcactac aaggacctcg agcccggcaa gtgggtcaag gtcctcggct
    16201 ggggtacggt ggaagacgcc aaggccgaga tcgtgaacgg cctggcggct gccaagaagt
    16261 aatcccggga gcacctgttt ccggatgacc cgaggcccac gcttgcgtgg gcctcggtcg
    16321 tttacggcgc cggcggggcg tgctgacggg cttggcggta ttttgtctgc caacgtcgct
    16381 gccgtggcag tccagtcgtg gatcaggcgt cgggttcgcg gcctgcgccc cagggcctgc
    16441 cggatgcgag ggctcttgta ggagcgccgg caggcgcgat ccctcggagg ccgagtggag
    16501 acgccgccac cttccgtgcc ctggcatcgc gcttgcttgt gtcatcatgg cgccacgtgc
    16561 tggctgggcg cgcacaaaca acaagacggg ggatccatgc ttgcgctgct gatgaagatc
    16621 aacaagaacc tgatcctcgc catcccggtg gcgatggtgc tcggcttcgg cttcgggctg
    16681 gtcgcgccgg tcggctggct gaagtcgctg atcgtgccgc tgaccttcct gatggtctat
    16741 ccgatgatgg tcaacctgaa gctctccaag gtgctcgaag gcggcgacct caaggcgcag
    16801 gcgctcgcgc aggcgatcaa cttcgccctc atccccttcg tcgcctacgc gctcggcaag
    16861 gccttcttcc ccgaccagcc cgcatacgcg ctcggcctgc tgctcgcggc actgctgcct
    16921 accagcggca tgacgatctc gtggaccggt ttcgccaggg gcaacctcgg cgccgcggtc
    16981 aagatgaccg tgctcgggct catcctgggc tcgctcgcca cgccgctcta cgtgcgctgg
    17041 ctgatggggg ccgaggtgcc ggtcgacatg ggcgcggtgt tcatgcagat cgtgatcatc
    17101 gtgttcctgc ccatgctggc cggtcactac acgcagaaat ggctggtggc gcgccacggc
    17161 caggctgcat acatgaagga gtggggaccg cgcttcccgc ctttttccac gctgggcgtg
    17221 ctcggcatcg tcttcgtcgc gctcgccctc aaggcgaagg acctcgtcgc tcagcccggc
    17281 gagctgatcg tggtgctggt gccgctgttg tgcctgtatg cgatcaacta cgtggtgagc
    17341 acggtggtgg cgcgcagcct gctgccgcgc ggcgacgcca tcgcgctggt gtacggcacg
    17401 gtgatgcgca acctgtcgat cgcccttgcg ctggcgatga acgtgttcgg ggcgtcgagt
    17461 tcgggtgcgg cgctggtgat cgcgctcgcc tacatcctgc aggtgcagtc cgcggcctgg
    17521 tacgtcaagc tcaccgatcg cgtcttcggc cctgccgcgc ccgcaaggac ggagggctga
    17581 gcgccggggc gtgggtgcgc cgggaaagtg ccgccggcgc gcctacgccc ccgcgcgaaa
    17641 gacgccctcg ccgggcgacc ggcccggctt gcgcttcagt ccggaatccg cgccacgtgc
    17701 agcaggttgg tgctgccacg ctggccgaag ggcaggccgg cgatcaccac cacggcgtcg
    17761 ccggcacggc cgaagcccag ggtcagcgcc gcgcgcgccg cgtgctcgac catctcggcg
    17821 acgtcatgca cctcctcgaa gggcaccgga tgtacgcccc acaccagcgc cagccgacgc
    17881 gcggtggcgg gctgcggcgt cagggcgagg atgggcgcca ccggacgctc gcggctggcg
    17941 cgcagcgcgc tgaagcccga gctggtgtag gccaccgtgg ccgcaggttc gagcaggccg
    18001 gcgacgcggc gcagcgcgca gcagatcgca tccggggtgt tcgccgcggc cggcgtgtgg
    18061 ctggcttcga gcccggcgcg ccaggcgggg tcgcgttcca cctcgcagac gatgccgtgc
    18121 atgatcgata ccgcctccac cgggtactgg cccgaggccg actcggccga cagcatcacc
    18181 gcgtcggcgc catcgtagat cgcggtggcc acgtccgagg cctcggcgcg ggtgggcacg
    18241 ggcgaggaga tcatcgactc cagcatctgc gtcgccacca ccaccgggcg gccggcggca
    18301 cgcgcggcgc gcacgatgcg gcgctgcagc accggcacct gctgcggcgg cagctccacg
    18361 ccgaggtcgc cgcgcgccac catgacaccg tcggcgagcg cgacgatcgg ctccagcgcg
    18421 tcgatcgccg ccggcttctc cagcttggcc atgatccagg cgcggtcgcc gacgagctcg
    18481 cgcgcctcgc gcaggtcctc ggggcgctgc acgaaggaca gcgccaccca gtccacgccc
    18541 agcgccaggc cgaagtcgag atcggcgcgg tctttggcgg tgagcggcga gatcggcagc
    18601 accacgccgg gcacgtttac gcccttgcgg tcggacagcg tcccgccgac gagcacggtg
    18661 gtttcggcga agtcggcgcc gcaggcgtct acccgcaggc gcagcttgcc gtcgtcgagc
    18721 agcagcgcgg tgccggcctc gagcgcggcg aagatctcgg ggtggggcag gttggcgcgg
    18781 cgggcgtcgc cgggcgtggg gtcgaggtcg aggcggaacg acgcgccggg cacgagggcg
    18841 accttgccct cggcgaagcg gccgacgcgc agcttgggcc cctgcaggtc catcagcacg
    18901 ccgatcgggc gcccgagctc ggcctcgacc gcgcggatca ggcgatagcg ctcggcgtgg
    18961 tcctcgtggc tgccgtggct gaagttgagc cggaacacgt ccgcgccggc ctcggccagg
    19021 gcgcggatgc gttcgcgggt ggaactcgcc ggcccgaggg tggcgaggat gcgggcgctg
    19081 cgttcgcgtt tcatgtcggg tcctcggcgg ttcaggcggg ggtgtgcgcg caggcgagca
    19141 gggcgtcgac cccggcgcgg gcgacgcggg cgtcctcgcc ggccttcacg ccggagaccc
    19201 ccaccgcgcc gaccacccgg ccatcgacca ccaccggctc gccgccttcg agcggcacca
    19261 ccggcatcgc cagcgcggcg aagcggccgt tgttcaccat gtcctcgaag gccttgctcg
    19321 gcttgccact gagtacgcag gtgcgtgcct tctcgggggc gacgatggcg ctcatcagcg
    19381 gcgcgccgtc catgcgttgc agccacaggg cgtggccgcc cgcatcgcag atcgcgatgc
    19441 tgaccgccca gccgttggcg cgcgcctcgg cctcggcggc tgcggcggcg acgcgggcgt
    19501 cggccagggt gagtgcgtgg gtggggatca tctacggtct ccgtctctct gtcgttctcg
    19561 tggggtgggc gagggcgcgc tcagcgctcg ccgaggtcgg tgaagcggat ccactgcgcg
    19621 cccttccaaa gcacggtgcg gcccatctcg tggagctgct cggcgccctc gacgacggtg
    19681 aggaagtggt tgccggcgag ctggcccatc ttgctggcga agcagctgct gccgtaggcg
    19741 aacaggatct cggtctcgga gaagccgccc gggtagagca ggaggtcgcc gcgcgagggg
    19801 tggctggtgt ggttctcgaa gcccagcccg gtgtcgaatt cgcccagcgg cacccacacc
    19861 gcctcgccgc tccagcgcga gtggatcacc tggttggaga acggcagcag ctcgaggaag
    19921 gcggcgcagg tcctgggcgc ggcgacttcc tccatgcggg cgacgaagcg gaaggagccg
    19981 acgtcgatgg cgagatggcg catgtcgtcc tccttactgg ccgatctcga agttggccat
    20041 cttctcgagc gcgcgcacca tgcccgagtg gtcccacttc gcaccgccgt gcgcgctgca
    20101 ggcgttgaag agctcctgcg cggtggcggt gttgggcagc gacacgccga gctggcgcgc
    20161 ggtggtcagc gcgaggttga ggtccttctg gtgcagctcg atgcgaaagc ccgggtcgaa
    20221 ggtgcgcttg accatgcgct cgccgtgcac ctcgaggatg cgcgagttgg cgaagccgcc
    20281 catcagcgcc tggcgcacct tggcggggtc ggcgccggcc ttggcggcga gcaacagggc
    20341 ctcgcccacc gcctcgatgt tgagtgcgac gatgatctgg ttggcgacct tggtgatctg
    20401 gccgtcgccg ttgccgccca ccagggtgat gttcttgccc atcagctcga agatcggctt
    20461 gaccatgtcg aaggccgcct cgctgccgcc gaccatgatg gtgagcgtcg ccgccttggc
    20521 gccgacctcg ccgcccgaca ccggcgcgtc gaggtattcg cagccgagcg cgttgatgcg
    20581 gcgggcgaag tccttggtgg ccaccggcga gatcgagctc atgtcgacca cgaccttgcc
    20641 cttcgacagc ccggcggcga cgccgtcggg cttgaacagc acgtcctcga cgtgcggggt
    20701 gtcgggcacc atggtgatga cgatgtcggc ctggcgcgcg acctcggcgc cgctcgcgca
    20761 tggctgggcg ccggcctcgc gcagcaccgc gggggtttcg ccgcgggtgt gggtgaagac
    20821 ggtgtgcccg cccttgatga ggttgcccgc catgggggtg cccatgatgc cgaggccgat
    20881 gaatccgatg tttgccatgt tgttgtctcc tcgatgaaga aaaaggtccc attcgcggct
    20941 gccgccgct
//
LOCUS       DAOTIN010000053        20487 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_3143_length_20487_cov_8.502007, whole genome shotgun sequence.
ACCESSION   DAOTIN010000053 DAOTIN010000000
VERSION     DAOTIN010000053.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 20487)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 20487)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20487
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3143_length_20487_cov_8.502007"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..268
                     /locus_tag="P5537_09555"
     CDS             <1..268
                     /locus_tag="P5537_09555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="Hpt domain-containing protein"
                     /protein_id="HRV78327.1"
                     /translation="RQQLHAAIAGTEIAQLARVAHRLRGALSQLRAAQAVALVKKIEA
                     YGKAHPDVCIARDHPLLAELDAELDALAGEVAAQLEALRQSGVS"
     gene            352..442
                     /locus_tag="P5537_09560"
     tRNA            352..442
                     /locus_tag="P5537_09560"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:386..388,aa:Ser,seq:gga)
     gene            complement(738..3857)
                     /locus_tag="P5537_09565"
     CDS             complement(738..3857)
                     /locus_tag="P5537_09565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011763747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HRV78328.1"
                     /translation="MTALHTEQTLEDEICRDLAAAGWLHEAGDAARYDRALALFPDDV
                     AGWIQTTQPEAWASIEQTHGANARKVVCERLRRTLADHGTLHVLRQGFEMLGLRRPIA
                     TAQFKPALAMNAELQAKYAANRLRVVRQLRYSLHNENCIDLGLFVNGIPVATCEIKTD
                     YTQAVEDAVLQYRKDRPPRVAGSNAVEPLLAFPQGALVHFALSNSAVRMTTRLDGFAT
                     VFLPFDKGDAGAAGNPPNPAGYATDYLWKAVWARDSWLEILHRYIVPRKNDARQLVNT
                     IFPRYHQLDATRAIVAAVRRDGPGDKYLIQHSAGSGKTNSIAWTAHFLADLHDSDNRK
                     VFDTVVVVSDRTVLDDQLQEAITGFERNRGVVAVVKGEGASKSQELAEALAAGKLIVV
                     CTLQTFPKALDKVRELAATEGKRFAVIADEAHSSQTNETAAKLKEVLSPAELAELADG
                     GEFDTEDLLAAQMQAKAAGKELGITFVAFTATPKDKTLQLFGTRPDPSRPPADDNLPA
                     PFHVYSMRQAIEEGFILDVLRNYTSYKVAFNLAHEGGARYSEVDRDAAVKGIMGWVRL
                     HEYNIAQRVNIVVEHFRQHVAPLLGGQAKAMVVTASRKEAVRWQLAMRKYIAEHGYGI
                     ETLVAFSGEVEDPESAPEPLAETSALMNPRLRGRGIREAFKGGDYAILLVANKFQTGF
                     DEPLLCGMYVDKRLAGIQAVQTLSRLNRAHPGKDTTYVVDFVNDPDEVLAAFRVYHTT
                     AELAGVSDPEQIYTLRAKLDGLGFYDTFEVDRVVEVVLRGKDQSALDRALVPVADRLI
                     KRHAAARRRLRDADEGSADAHAARLELDALVLFKRDIATYVRLYGFLSQIFNYGNTDI
                     EKRAIFLRLLHKVLDFGRESETVDLSSLALTHYTLKNLGTRRLALDAGQGEYKLQPSG
                     PGGGEVRDKQKAALDEIIARVNQLFIGELTEGDKLLYVNNAIKGKLLECETLIEQAVN
                     NTKEQFGNSPDLDARILDAVMDALSAFTSMSRQALESERIRAEIKSILLGPGRLYELL
                     RAQAAGGRG"
     gene            complement(3924..4298)
                     /locus_tag="P5537_09570"
     CDS             complement(3924..4298)
                     /locus_tag="P5537_09570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HRV78329.1"
                     /translation="MSKLTIKTGTEEDFFKRGRRLAKMADLGERLPEERILSFEDPAD
                     VMKLITATRLALFRTVKETPGSITEIADRLHRDRSAVKRDIDELARAGLVTVAEKVLP
                     GHGRMKEVRAAASRFSLQAEIS"
     gene            complement(4295..4594)
                     /locus_tag="P5537_09575"
     CDS             complement(4295..4594)
                     /locus_tag="P5537_09575"
                     /inference="COORDINATES: protein motif:HMM:NF039803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6516 family protein"
                     /protein_id="HRV78330.1"
                     /translation="MPEIKTIDETHTISDRRGNGKLRREVWVDKATGRVTRYNLAYIN
                     HKLFAGDNGRVVGYDNAHDGHHRHYFGVVEPVEFVSFEDVEERFEEDWISLRSSK"
     gene            complement(4691..5797)
                     /locus_tag="P5537_09580"
     CDS             complement(4691..5797)
                     /locus_tag="P5537_09580"
                     /inference="COORDINATES: protein motif:HMM:NF025454.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4268 domain-containing protein"
                     /protein_id="HRV78331.1"
                     /translation="MAIFEITQTGLKPVAETRFDAEGLKERADIQRLVRENINILEDG
                     LMVIAEEFGEWMDSSRRIDLLCLDTDANLAVVELKRTIDGGHMELQAIRYAAMVSAMT
                     FDQLIDVHARFLNRGSPNTEGARAAILDFLGWATPDEERFGEDVRIILASADFGKELT
                     TAVVWLNDRGLDIRCVRLKPYKIADGRILLDVQQLIPLPEVAEFQTQIGIKKQAERSQ
                     SNSRHEARLKWWAALLEYARTQTPLHAGRSPTRDTWISGSGGRAGFAMIYTTRETEAQ
                     VQVWIGLGAGRDAENKRAFHALKAHQAQIEQAFGAPLDWLEMPGRSGCRICKVYPGGY
                     RSPVEEWPELHRTLVAAMVRLHGAFADTIRTLQF"
     gene            complement(5929..7305)
                     /locus_tag="P5537_09585"
     CDS             complement(5929..7305)
                     /locus_tag="P5537_09585"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF013579.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HRV78332.1"
                     /translation="MSFPRYPDYKDSGVEWLGEVPGHWATPPLYLRYSVELGKMLDSS
                     RITGDHLVPYLRNVDVQWGRINFDDLPEMDIEESEYGRYTVAPGDLLVCEGGEVGRAA
                     IVPERSGTIGFQKALHRLRALADDEHPAFMYFVLSWAALRGVFSQSGLSTIAHLTGEQ
                     LRKYRFPKPPIPEQVQIAAFLDRETGKIDTLVAEQQNLIALLKEKRQALISHAVMKGL
                     DPDVRMKDSGMAWLGEVPAHWRVCALRRAIAEIEQGWSPDCHARPAEAGEWGVLKAGC
                     VNGGKYRPTENKALPSELLPDESYCVEVGDVLMSRASGSPDLVGSTALVRETPGRLML
                     SDKIFRLRLEIDVDPAFFVAMLNARALRAQIEQALSGGNGLANNLPQSNLLAFVCALP
                     PEEEQIAIAARLNRDIEGLDQLMAEAESTISLLIERRTALISAAVTGKIDVRHLAVAS
                     ADRTPEPA"
     gene            complement(7712..9547)
                     /locus_tag="P5537_09590"
     CDS             complement(7712..9547)
                     /locus_tag="P5537_09590"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011763741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent DNA methyltransferase"
                     /protein_id="HRV78333.1"
                     /translation="MNQQALSALIWSVADLLRGDFKQSEYGRVILPFTVLRRLDCVLA
                     PTKAAVLAEYRDKEQVGLPFEPFVLRKSGVPFYNVSALDLPTLAGDQDHLRANLHAYI
                     QGFAPDVRDIFEHFDFANTVERLHKAGLLYLVVEKFAHIELHPRRVDNVHMGLVFEEL
                     IRKFAEISNETAGEHFTPREVIRLMVSLLFIEDDEALTRPGIVRTIYDPTAGTGGMLS
                     VAGEHLHDINPGARMSMYGQELNPESYAICKADMLIKGQDVRNIVLGNTLSEDGLLGK
                     LFDYMLSNPPFGVEWKKVEKEVRREAEDKGFAGRFGPGLPRVSDGSLLFLLHLISKMR
                     PAEQGGSRIGIVLNGSPLFTGGAGSGESEIRRYLLENDLVEAIVGLPTDMFYNTGIST
                     YVWILTNRKVEDRKGWVQLIDASSFWHKMRKSLGSKRKELSDAHIAEITRLLGEFLEA
                     EQAVVNDAQGKELERVTLFPEVRCPAAPEGGKVKRVPIARVFRNEDFGYRTITIERPQ
                     RDAAGHIVLGERGKQKGKPQPDSALRDTENVPLSEDVQAYFEREVLPHAPDAWIDHDK
                     TKVGYEIPFNRHFYVFEPPRPLAEIDADLKRSMDRIKQMIEGLAG"
     gene            complement(9680..10801)
                     /locus_tag="P5537_09595"
     CDS             complement(9680..10801)
                     /locus_tag="P5537_09595"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78334.1"
                     /translation="MDFLLALDVLLGLSLIYLVFALAVTSINEFIAAALSSRARWLRR
                     GIASLLSADPRSLDTERADEVLDSPFLSHLGTRGVWKTFRVSYVSAWQLTQGVLSQVQ
                     GFKEDAFARVGDIRALAEQLPANAPMRSALIDLCARANGDLAKFQLMLDDWFKTFEDQ
                     LTAWYRQKTQYVLVGISFFVVLTMNVDTIDLARQLSADPRVRAQLVEQAMKVADAADL
                     AALLDTAGRDRARKEHEEALKRRDEAEKGFRSACQAPEVEEASARACADATGRQDEAR
                     REEVAKRAALAAEQKALDSRVKERADALSASGLMIGWKGGEFAQALAGGNWLAKLVGL
                     LLSGFAIALGAPFWFNVLKSVASVRSVGANVKEKADSAG"
     gene            complement(10844..11626)
                     /locus_tag="P5537_09600"
     CDS             complement(10844..11626)
                     /locus_tag="P5537_09600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004315804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HRV78335.1"
                     /translation="MAAYWDEAAMQRVLVMPSILAIGDSWFWYPFPGGSLIRYLGPIV
                     ERKEHTILAYGMNGAEAFDYIDGKYKDRITGALRRYGNSLSAVFISGGGNDFAGFNDM
                     RPLLALDCSGAQSAADCFRSGDGGLGHFLERMDDHYRRLIGLIYTHTSLDCRILMHSY
                     DYAIPDGRGVAGKAGWLKPALVDAGVPEALQRDCVRYLIDAFHAMLGRVAAGDPAHLL
                     IVDSRGTLAEKDWANELHPKGKGFKKIAKERWKPVLKGAGLA"
     gene            complement(12307..12645)
                     /locus_tag="P5537_09605"
     CDS             complement(12307..12645)
                     /locus_tag="P5537_09605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018990471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HRV78336.1"
                     /translation="MRNIQIFELSQGGSGAVPDEAAADFAADVAWAKEQGAHIERFSF
                     AEQPDEFARNAVVEDFVERSGYDALPLALVDGELAVAGRHPTRNELARWAGLAQPVAA
                     GGCCSGGHCG"
     gene            complement(12944..13264)
                     /locus_tag="P5537_09610"
     CDS             complement(12944..13264)
                     /locus_tag="P5537_09610"
                     /inference="COORDINATES: protein motif:HMM:NF036549.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78337.1"
                     /translation="MHELKWTQAEKKAARGLFDVALGREMTDYIARFKASAAAIETPD
                     ALWALLREAEQKRRELDERYDFRYSVLVFVFAGLLRRGLIDEAELAALGEGKAHLIAE
                     LAKM"
     gene            complement(13295..14260)
                     /gene="dmeF"
                     /locus_tag="P5537_09615"
     CDS             complement(13295..14260)
                     /gene="dmeF"
                     /locus_tag="P5537_09615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family Co(II)/Ni(II) efflux transporter
                     DmeF"
                     /protein_id="HRV78338.1"
                     /translation="MPTDNLSAWTHDHVFDTGNALAERSTWVVMWITAAAMVIEITAG
                     WWFNSMALLADGWHMSSHAFAIGLSALAYAAARRYAQDRRFAFGTWKIEILGGFASAI
                     FLLGVAAMMVVGSIERIVSPQAIQYREAIAVAILGLAVNLACALILGKAHHHGHDHHH
                     GHDHPHHDLNLKSAYLHVIADAATSVLAIVALVGGWIYGWSWLDPVMGIVGAVLVAVW
                     AKGLLVETGRVLLDREMDHPVVAEIREVVESGPQADDTRIIDLHVWRVGKEAYSCAIA
                     VVTRDGALTPDAVRARLAVHEEIVHSTIEIHHHNGFREAPGGAGA"
     gene            complement(14269..14547)
                     /locus_tag="P5537_09620"
     CDS             complement(14269..14547)
                     /locus_tag="P5537_09620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001120768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal/formaldehyde-sensitive transcriptional
                     repressor"
                     /protein_id="HRV78339.1"
                     /translation="MSHTIRDKAKLLARVRRIRGQVEALERALEAGKECAEILHQIAA
                     VRGATNGLMAEVLEEHVRTHIADPAITDAAERTKGADELIGVLRTYLK"
     gene            14911..15096
                     /locus_tag="P5537_09625"
     CDS             14911..15096
                     /locus_tag="P5537_09625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78340.1"
                     /translation="MNNQASGHSAPSGVQAPGRPGEWRRFLLLAFIGLPITMTLAIAA
                     YGFVVWFLQILVFGPPS"
     gene            15173..16396
                     /gene="torC"
                     /locus_tag="P5537_09630"
     CDS             15173..16396
                     /gene="torC"
                     /locus_tag="P5537_09630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentaheme c-type cytochrome TorC"
                     /protein_id="HRV78341.1"
                     /translation="MTNLLRSLRDLFLKPAVRIGLGVLVTGGFIAGVLAWQGFNTAME
                     ATNKEEFCLSCHTMHDNLLPELQKTVHWNNRTGVRARCPDCHVPHDFTDKVARKMQAS
                     REVLGQLLGTIDTREKFKEHRIVLAQREWKRFSANGSKECRACHDYKDMDFDKMRPAS
                     QVAMRKAAERNQSCVDCHKGVAHQLPEMKGARNPAFDTLVSSAAGQSVDAGKDYFLVV
                     PQELYADEGMTKRIGAIEVATQVKVLETKGDAQRVELALWRKNKGYGRVWYSHFGLNI
                     TSAVLDKEVAQDASFVKVLDTREDPMTGLEWQQVTASAWMRKGSVLDSVEPVWSIARA
                     SYSSSCSVCHRQPEEAHFDANTWPGLFGGMVGFTSMDDDTARVVLKYPQTHSSDFSTS
                     HGAGSPDSALQTARP"
     gene            16413..18929
                     /gene="torA"
                     /locus_tag="P5537_09635"
     CDS             16413..18929
                     /gene="torA"
                     /locus_tag="P5537_09635"
                     /EC_number="1.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA];
                     GO_function: GO:0030151 - molybdenum ion binding [Evidence
                     IEA];
                     GO_function: GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA];
                     GO_function: GO:0050626 - trimethylamine-N-oxide reductase
                     (cytochrome c) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimethylamine-N-oxide reductase TorA"
                     /protein_id="HRV78342.1"
                     /translation="MNYSRRGFLKALATMSGSALVAPALLASRSALAAGEAAAVGDDI
                     TTWKISGSHFGAIRAKVVGDRVVDIRPFELDKHPTEMIKGLLGLIYSPSRVRYPMVRL
                     DWYRKRHLSDTSQRGDNRFVRVSWDEALDLFYEELERIQKDYGPWALHTGGVGWRSVG
                     QVHSCGNHMVRGVGMHGRSVGTIGDYSTGAGQMILPYVLGSTEVYSQGTSWDVILKES
                     KLVVFWANDPVKNLQVGWNTETHESYAYFEQLKQKVADKSIQAICIDPVKSKTLDYLG
                     GAEHQYIHPMTDVPLMLAIAHTLVKEGLHDQKFLDTYTLGFDRFLPYLQGKTEDMVEK
                     TPEWAEQICGVPAERIRELARLMARHRTQLIFGWAVQRQQHGEQPYWMGAVLAAMLGQ
                     IGLPGGGISYAHHYSSVGVSSSGAAMPGAFPLNLDPGRKPRHDNTDFKGYSAVVPIAR
                     VIDALLEPGKEIDFNGGKVKLPPYKMAIFSGCNQWHRQPQRNRMKEAWRKLETVVAID
                     YNWTATCRFADIVLPACTPFERNDLDGYGSYSNRGIIAMQKLIDPLFHSRPDFEIFRG
                     LTRRFNRDAEYTRGMDEMQWVEKIYEDCRKENGLKDIAMPPFAEFWQKGYVMFPEGKP
                     WVRHADFRDDAEVNALGTPSGFIEIFSRKIERYGYADCKGHPVWMEKTERSHGGPGSD
                     RFPLWLQSVHPDKRLHSQLCESEPLRETYAIAGREPVFIGPEDAAARGIQHGDLVRVF
                     NDRGQLLAGAHVSDNFPRGVVRIQEGAWYGPTGPEIGALDTYGDPNTLTLDIGTSSLA
                     QATSANTCLVQIEKFVGTAPAVTSFGGPIEVDPEGREVKA"
     gene            19052..19729
                     /gene="torD"
                     /locus_tag="P5537_09640"
     CDS             19052..19729
                     /gene="torD"
                     /locus_tag="P5537_09640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051259 - protein complex oligomerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone TorD"
                     /protein_id="HRV78343.1"
                     /translation="MPLSHEEWQFAGTQRAGLYGWFARLYAEEVSEPVYRSHFADGGF
                     APFAGLAELSLEAEVQRLDAAIATLRAEQLPRLELAADFAQLFLLDGKTSALPYASAY
                     TGTDGASPLFGAAEARMRDFLAASGLSIQADFREPADHLAVPLALMAELAGAASSAED
                     IPTAAAAQADFLRTAVLDWLPRFVERCQQARPRFDVYPALAALLLGFVRADVAFLEDV
                     GGSAAVS"
     gene            complement(19758..20195)
                     /locus_tag="P5537_09645"
     CDS             complement(19758..20195)
                     /locus_tag="P5537_09645"
                     /inference="COORDINATES: protein motif:HMM:NF021873.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2442 domain-containing protein"
                     /protein_id="HRV78344.1"
                     /translation="MKTPPRIETARVTGDLKLEIGWSTGETLPVDLSDLAQPPFDALR
                     TPDFFARMTRDEWGHGLDWPDGLGLGADRLYELSRRQAGLPTASEFNDWMQRNGLSLA
                     SAAESLGMTRRMIAHYRTGSRPIPKVVGLACLGWESRRRQRAA"
     gene            complement(20192..20425)
                     /locus_tag="P5537_09650"
     CDS             complement(20192..20425)
                     /locus_tag="P5537_09650"
                     /inference="COORDINATES: protein motif:HMM:NF025088.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4160 domain-containing protein"
                     /protein_id="HRV78345.1"
                     /translation="MTNYDIVGDWRIRINGMEHGVPHVHVISRDGSRVSVAIETGEVL
                     VGGVQPLKRLVAALADIRANKAKYLDEYRRLNP"
BASE COUNT         3405 a         7048 c         6602 g         3432 t
ORIGIN      
        1 ccgccagcag cttcacgcgg ccatcgcagg caccgagatc gcgcagctgg cgcgcgtcgc
       61 ccatcgcctg cgcggcgcct tgtcgcagct gcgtgccgcc caggcggtcg ccctggtgaa
      121 gaagatcgag gcgtacggca aggcccaccc cgacgtctgc atcgctcgag accatccctt
      181 gctggccgag ctcgacgccg aactcgacgc cctcgccggc gaagtcgcgg cgcagctcga
      241 ggcgctgcgg cagtcaggcg tatcgtgacc ggaggggcga cggcgggcag cgcagcgcac
      301 aaaaagcgct ttctaatccc tgcccttgcg gctataatgc cgcgcttccc cggacaggtg
      361 gatgagtggt ttaagtcgca cgcctggaaa gcgtgtttgg gataatatcc caacgcgggt
      421 tcgaatcccg ccctgtccgc cagaacacca gcaatcaagc gccctccggg gcgctttttt
      481 gtttcacccc acatccaacc ccacttcccg aaaacgctta gacgatggga agtgcaggtc
      541 gcatcgtcac cagctcgccg gtcgcaccgc gcgtcgtgga agccttggcg ctcgagcccc
      601 tttcggcgtc gttcgcttgt agccgtcgcc acgacgccag tcgagaggcc atttcccggc
      661 gcgctcgtgc agcgggcgtg gctgtggtcg ccgagtacgc gtcaagaaag accgcgccgg
      721 tgtcggacat tcgagatcta gccgcggccg cccgcagcct gcgcgcgcag aagctcatac
      781 agccgccccg ggccgagcag gatggacttg atctcggcgc ggatgcgctc ggactccagc
      841 gcctgccggc tcatcgacgt gaacgccgac aacgcgtcca tcaccgcgtc caggatgcgc
      901 gcatccagat cgggcgaatt gccgaactgc tccttggtgt tgttcaccgc ctgctcgatc
      961 agcgtctcgc actccagcaa cttgcccttg atcgcgttgt tcacgtagag cagcttgtcg
     1021 ccctcggtga gctcgccgat gaagagctgg ttcacccgcg cgatgatctc gtcgagcgcc
     1081 gccttctgct tgtcgcgcac ctcgccgccg ccggggccgc tgggctggag cttgtactcg
     1141 ccctgcccgg cgtccagcgc caggcggcgg gtgccgaggt tcttgagcgt gtagtgggtc
     1201 agcgcgagcg aggacaggtc gacggtctcg ctctcgcggc cgaagtcgag caccttgtgc
     1261 agcaggcgca agaagatcgc gcgcttctcg atatcggtgt tgccgtagtt gaagatctgc
     1321 gacaggaagc cgtacaggcg cacgtaggtg gcgatgtcgc gcttgaaaag gaccagcgcg
     1381 tcgagctcca gccgggcggc gtgggcgtcg gcgctgcctt catccgcgtc gcgcaggcgg
     1441 cgccgggcgg cggcgtggcg cttgatcagg cggtcggcca ctggcaccag ggcgcgatcg
     1501 agcgcggact ggtccttgcc gcgcagcacc acctcgacca cgcgatcgac ctcgaacgtg
     1561 tcgtagaagc ccagcccgtc gagcttggcg cgcagggtgt agatctgctc ggggtcgctg
     1621 acgccggcga gctcggcggt cgtgtgatag acgcggaagg cggcgaggac ctcgtcgggg
     1681 tcattgacga agtcgaccac gtaggtggtg tccttgcccg gatgcgcgcg gttcaggcgc
     1741 gacagcgtct gcacggcctg gatgccggcc aggcgcttgt ccacgtacat gccgcacagc
     1801 agcggctcgt cgaagccggt ctggaacttg ttggccacca gcaggatggc gtagtcgcca
     1861 cccttgaagg cctcgcggat gccgcgcccg cgcaggcgcg ggttcatcag cgcgctggtc
     1921 tcggcgagcg gctcgggcgc ggactccggg tcttcgacct cgcccgagaa cgccaccagg
     1981 gtctcgatgc cgtagccgtg ctcggcaatg tacttgcgca tcgccagctg ccagcgcacc
     2041 gcctccttgc ggctggcggt caccaccatg gccttggcct ggccgccgag cagcggcgcg
     2101 acgtgctggc ggaagtgctc caccacgatg ttcacgcgct gggcgatgtt gtactcgtgc
     2161 agccgcaccc agcccatgat gcccttcacg gcggcgtcgc gatcgacctc ggaatacctg
     2221 gcgccgccct cgtgcgccag gttgaaggcc accttgtagc tggtgtagtt ccgcagcacg
     2281 tcgaggatga agccctcctc gatcgcctgc cgcatcgagt acacgtgaaa gggcgcgggc
     2341 aggttgtcat cggcgggcgg gcggctcgga tccggccggg tgccgaagag ctgcagcgtc
     2401 ttgtccttgg gcgtggcagt gaaggcgacg aaggtgatgc ccaactcctt gccggccgcc
     2461 ttggcctgca tctgcgcggc gagcagatcc tcggtgtcga actcgccgcc gtccgccagt
     2521 tcggcgagct ccgccggcga cagcacctcc ttcagcttgg ccgcggtctc gttggtctgc
     2581 gaggaatgcg cctcgtcggc gatcaccgcg aagcgcttgc cctcggtcgc cgccagctcg
     2641 cgcaccttgt cgagcgcctt gggaaaggtc tgcagcgtgc acaccacgat caacttgccg
     2701 gcggcgagcg cctcggcgag ctcctggctc ttgctcgcgc cctcgccctt gaccaccgcg
     2761 accacgcccc ggttgcgctc aaagccggtg atcgcctcct gcagctggtc gtcgagcacg
     2821 gtacggtccg acaccaccac caccgtatcg aagaccttgc ggttgtcgga gtcgtgcagg
     2881 tcggcgagaa agtgcgcggt ccacgcgatc gagttggtct tgcccgagcc ggccgagtgc
     2941 tggatcaggt acttgtcgcc cggcccgtcg cggcgcaccg cggcgacgat ggcgcgggtg
     3001 gcgtcgagct ggtggtagcg cgggaagatg gtgttcacga gctgccgggc gtcgttcttg
     3061 cgcggcacga tgtagcggtg gaggatctcc agccacgaat cgcgcgccca caccgctttc
     3121 cacagatagt cggtggcgta gcccgccggg ttgggcgggt tgcccgcggc gccggcgtcg
     3181 cccttgtcga aaggcaggaa cacagtggcg aagccatcga gcctggtcgt catccgcacc
     3241 gccgaattgc tcagcgcgaa atgcaccagc gccccctgcg gaaaggccag cagcggctcc
     3301 accgcgttgc tgcccgccac gcgcggcggg cggtccttgc ggtactgcag cacggcgtct
     3361 tccaccgcct gggtgtagtc ggtcttgatc tcgcaggtcg ccaccgggat gccgttcacg
     3421 aacagcccga ggtcgatgca gttctcgttg tgcagcgaat agcgcagctg gcgcaccacg
     3481 cgcaggcggt tggcggcgta cttcgcctgc agctcggcgt tcatcgccag cgcgggcttg
     3541 aactgcgccg tcgcgatcgg ccgccgcagc cccagcatct cgaagccctg gcgcagcacg
     3601 tgcagcgtgc cgtggtcggc cagcgtgcgg cgcaggcgct cgcacaccac cttgcgcgcg
     3661 ttggcgccgt gggtctgctc gatgctcgcc caggcctcgg gctgcgtcgt ctggatccag
     3721 cccgcgacgt cgtccgggaa cagcgccagc gcgcggtcgt agcgcgccgc gtcgcccgcc
     3781 tcgtgcagcc agccggcggc ggcgaggtcg cggcagatct cgtcttctag ggtttgttcg
     3841 gtgtggaggg cggtcatcgg gaggcggtgc aggtcttgaa cggattcgtc atggcgttgg
     3901 agaagtcatt aacgcgccgc caatcaggaa atctcggcct gcagactgaa ccggctcgcc
     3961 gccgccctga cttccttcat gcgcccgtga cctggcagca ccttctccgc cacggtcacc
     4021 aagccggccc gcgccaactc atcgatgtcc cgctttaccg cactgcgatc gcgatgcaga
     4081 cgatccgcaa tctcggtgat cgaaccgggc gtttccttca ccgtccggaa cagggcgaga
     4141 cgcgtcgccg tgatcaactt catcacgtcg gcagggtcct cgaagctgag aatgcgttcc
     4201 tccggtaggc gctcgccaag atccgccatc tttgccagcc tgcgcccacg cttgaagaag
     4261 tcctcttcgg ttcccgtctt gattgtgagc ttgctcattt actgctcctc agcgaaatcc
     4321 agtcttcctc gaaccgctct tcgacatcct cgaagctgac gaattcgacg ggctctacaa
     4381 ctccgaagta gtggcgatgg tgaccgtcgt gggcattgtc gtaaccgacg acccgcccgt
     4441 tatcgcctgc aaaaagtttg tggttgatgt atgcgaggtt gtagcgcgtc acacgccccg
     4501 tggccttgtc gacccagacc tcccggcgca gcttgccgtt gccgcgccta tcggaaatcg
     4561 tgtgcgtttc gtcgatggtc ttgatttcag gcatgaccta gattatcacg gctgagactt
     4621 gccattgggg agagacgcca agtcacccgc gcctgccggg gcccgtcgtc atcctgacag
     4681 ccaccgaagc ctagaactgc agcgtccgga tggtgtcggc gaacgcgcca tgaagcctaa
     4741 ccattgcggc cacgagcgtc cgatgcaatt cgggccactc ctctacaggc gatcgatagc
     4801 cgccgggata taccttgcag attcggcatc ccgaccttcc gggcatctcc agccagtcca
     4861 gcggcgcacc gaaggcctgc tcgatctgcg cctgatgggc cttcagcgcg tggaaagctc
     4921 tcttgttctc agcatcgcgc cccgccccta aaccaatcca gacctgcact tgcgcttcgg
     4981 tctcgcgagt ggtgtaaatc atggcaaagc cggcccgacc cccgcttcct gagatccacg
     5041 tgtcgcgggt agggctgcga cccgcatgga gcggcgtctg cgtgcgcgcg tattcgagca
     5101 aggcagccca ccacttcaga cgcgcctcgt gacggctgtt gctttgcgag cgctcagcct
     5161 gcttcttgat gccgatctgg gtctggaact cggcgacctc cggcagcgga atcaactgct
     5221 ggacgtcgag caaaatgcgc ccgtcggcga tcttgtaggg tttgagcctg acacagcgta
     5281 tatcgagtcc tcggtcgtta agccagacca cggctgtcgt tagctcctta ccgaaatcgg
     5341 cggacgccag gatgatgcgg acgtcctcac caaagcgttc ctcgtcaggc gtcgcccagc
     5401 cgagaaagtc gaggattgca gcccgtgcgc cctcggtgtt cggacttccc cgattcagga
     5461 aacgtgcatg cacatcgatg agttgatcaa aagtcatcgc cgacaccatg gctgcatagc
     5521 ggatagcctg cagttccatg tggccgccat cgatcgtgcg tttcagttca acaacggcaa
     5581 gattcgcgtc ggtatcgaga catagaagat cgattcgacg gctgctgtcc atccactcgc
     5641 cgaactcctc ggcgatgacc atgagcccgt cctcaaggat gttgatgttc tcgcgaacaa
     5701 gccgctggat gtcagcacgc tcctttagcc cctccgcgtc gaaccgtgtt tcagcgaccg
     5761 gcttcagacc ggtctgagtg atctcgaaaa ttgccattgg tattccttgc tagtcgcgta
     5821 atggcgagcg cccgggacaa cgagtgcctg gccccgattc gatgcggatg cggcgcgggt
     5881 cgccgagggc gagggcgatc tggatggtct gcgggcgcgc ggcgggggtc atgcgggctc
     5941 cggggtgcgg tcggcggagg cgacggcgag gtggcggacg tcgatcttgc cggtgacggc
     6001 ggcggagatc agggcggtgc ggcgttcgat tagaagactg attgtcgact ccgcctcagc
     6061 catcaactga tcgaggcctt cgatgtcacg attcagtcgt gcggcgatcg caatctgctc
     6121 ttcctcaggc ggcaaagcac aaacgaacgc aagcaagttc gactggggca gattgttcgc
     6181 caggccgttg ccaccactca gcgcctgctc gatctgcgcc cgcaaggcgc gagcgttcaa
     6241 catcgccaca aaaaatgccg gatcgacatc gatctcaagg cggagccgga agatcttgtc
     6301 ggaaagcatc agacgccctg gcgtctcccg caccagcgcc gtcgatccga ccaagtcggg
     6361 cgagccactc gcgcgagaca tgaggacatc gccgacctcc acgcagtagg actcgtcagg
     6421 cagcaactcc gacgggagcg ccttgttctc ggttggacgg tacttgccgc cattgacgca
     6481 cccggccttg agcacgcccc actcgcccgc ctcggcggga cgcgcatggc aatcgggact
     6541 ccacccctgt tcgatctcgg cgatcgcgcg ccgcagcgca cagactcgcc aatgcgccgg
     6601 cacctccccc agccacgcca ttccggaatc cttcatccgc acatccggat ccagcccctt
     6661 catgactgcg tgcgagatca gcgcctgacg cttttccttc agcagcgcta tcaggttctg
     6721 ctgctcggcg acgagggtgt cgatcttccc ggtttcgcgg tcgaggaagg cggcgatctg
     6781 cacctgttcg gggatcggtg gcttgggaaa gcggtactta cgaagctgct cgcccgtcag
     6841 atgcgcaatc gtcgatagcc cgctttgact gaacacgccc cgaagcgccg cccaggaaag
     6901 cacgaaatac atgaacgcgg gatgctcgtc gtccgccaac gcgcgcagcc tatggagcgc
     6961 cttctggaag ccgatcgtgc cgctcctctc cggaacgatc gccgcacgcc cgacctcgcc
     7021 tccttcgcaa acgagcagat cacccggcgc caccgtgtag cgaccatatt ccgactcctc
     7081 gatgtccatc tcgggcaagt catcgaagtt gatccggccc cactggacat cgacgttgcg
     7141 aaggtacgga acgaggtggt cgccggtgat ccgcgacgag tcgagcatct ttccgagctc
     7201 gaccgagtag cgaagataaa gcggcggggt agcccaatgc cccggcacct cccccagcca
     7261 ctcgacgccc gagtccttgt agtcgggata gcgtggaaag ctcatcgcgc cagtccctcc
     7321 cgcgtcccca tcacggcctg accttttcgt cgcgctggcg gtgcgacttt tccacgtagc
     7381 gcgaccggcg aaatgctgtc agcagcgccg gcacgattaa aaaccctgga cgcaaaaaac
     7441 ccgccgaaga gcgcttcttc gagaggcatg gcgggtgtgt tgtccaggac gacagccgcg
     7501 tcccgggaaa agagtaaccc ccaggtttgt gcgtgccgcg catgcgcgtc ggtagaggca
     7561 ttgggggttt tgttgggcac gattctaacg cgcgccgagc agtttcggcc cgacagtttc
     7621 cttgcgacgc aggcctggcc cgcgccacgc tgcggcattt gtctcatcgc tgccgagaca
     7681 atcccgtcct gcggtctctg gtcccgatcc ctcatcccgc caacccctcg atcatctgct
     7741 tgatccgatc catcgagcgc ttcaggtccg cgtcgatctc cgccagcggt cgcggcggtt
     7801 cgaagacgta gaagtggcgg ttgaagggga tctcgtagcc gaccttggtc ttgtcgtggt
     7861 cgatccaggc atcgggggcg tggggcagca cctcgcgctc gaagtaggcc tgcacgtcct
     7921 cggacagcgg cacgttctct gtgtcgcgca gcgcgctgtc gggctggggc ttgcccttct
     7981 gcttgccgcg ctcgccgagc acgatgtggc cagcggcgtc gcgctgcggg cgctcgatgg
     8041 tgatcgtgcg gtagccgaag tcctcgttgc ggaagacgcg ggcgatgggc acgcgcttga
     8101 ccttgccgcc ctcgggcgcg gccgggcagc gcacctcggg gaagagcgtg acgcgctcga
     8161 gctccttgcc ctgggcgtcg ttcaccaccg cctgctcggc ctcgaggaat tctccgagca
     8221 ggcgggtgat ctcggcgatg tgggcgtccg acagctcctt gcgcttggag ccgaggctct
     8281 tgcgcatctt gtgccagaag ctcgaggcgt cgatcagttg cacccagccc ttgcggtcct
     8341 cgaccttgcg gttggtgagg atccacacgt aggtgctgat gccggtgttg tagaacatgt
     8401 cggtgggcag gccgacgatg gcctcgacca ggtcgttctc gagcaggtag cggcggatct
     8461 cggactcgcc cgagccggcg ccgccggtaa acagcggcga gccgttgagc acgatgccga
     8521 tgcggctgcc gccctgctcg gccgggcgca tcttggagat caggtgcagc aggaagagca
     8581 gcgagccgtc cgacacgcgc ggcagtcccg gcccgaagcg gccggcgaag cctttgtcct
     8641 cggcctcgcg gcgcacctcc ttctcgacct tcttccactc cacgccgaag ggcgggttgc
     8701 tgagcatgta gtcgaacagc ttgccgagca ggccgtcctc ggacagcgtg ttgccgagca
     8761 cgatgttgcg cacgtcctgg cccttgatca gcatgtcggc cttgcagatg gcgtaggact
     8821 cggggttgag ctcctggccg tacatgctca tgcgcgcgcc cgggttgatg tcgtgcaggt
     8881 gctcgcccgc caccgacagc atgccgccgg tgccggcggt ggggtcgtag atggtgcgca
     8941 cgatgccggg ccgggtcagg gcctcgtcgt cctcgatgaa gagcaggctc accatcaggc
     9001 ggatgacctc gcgcggggtg aagtgctcgc cggcggtctc gttggagatc tcggcgaact
     9061 tgcggatcaa ctcctcgaag accaggccca tgtgcacgtt gtcgacgcgg cgggggtgga
     9121 gctcgatgtg ggcgaacttc tccaccacca ggtagagcag cccggccttg tgcaggcgct
     9181 cgacggtgtt ggcgaagtcg aagtgctcga agatgtcgcg cacgtcgggc gcgaagccct
     9241 ggatgtaggc gtgcaggttg gcgcgcaggt ggtcctggtc gccggcgagc gtgggcaggt
     9301 cgagggcgct gacgttgtag aagggcacgc ccgacttcct gagcacgaag ggctcgaagg
     9361 gcagcccgac ctgctccttg tcgcggtact cggcgagcac cgccgccttg gtcggcgcca
     9421 gcacgcagtc gagccggcgc agcacggtga agggcaggat gacgcggccg tattcggact
     9481 gcttgaagtc gccgcgcaag aggtcggcga ccgaccagat gagggcggag agggcttgct
     9541 ggttcatgcg gttgttcttg taggtgcgtt acctacgcat tatgaccgac cgactcaagg
     9601 agtttgttgc gtctcgccat cgatccagct gctcgcagac gcgtgggacg atgggggctc
     9661 ctgcatcccg cctcagcgat caccccgccg aatccgcctt ctccttcacg ttcgccccca
     9721 ccgagcgcac cgacgcgacc gatttcagca cgttgaacca gaacggcgca ccgagcgcaa
     9781 tcgcaaagcc ggatagcagc aagcccacca gcttggccag ccagttcccg cctgccaggg
     9841 cctgtgcgaa ctcgccacct ttccagccga tcatgagccc gctcgcggac aaggcgtccg
     9901 cccgctcctt gaccctcgag tccagggcct tctgctcggc ggcgagcgcc gccctcttcg
     9961 ccacctcttc gcgccgtgcc tcgtcctgcc tgccggtggc gtcggcgcag gctcgcgcag
    10021 acgcctcctc cacctcgggc gcctgacaag ccgaacggaa gcctttctcc gcctcatcgc
    10081 gacgcttgag ggcttcctca tgctccttgc gtgcgcgatc gcgtcccgcc gtgtcgagaa
    10141 gggccgcgag atcggcggcg tcggccacct tcatggcctg ctcgaccagc tgggcccgca
    10201 ccctggggtc ggcggacagc tgccgcgcca gatcgatcgt gtcgacgttc atcgtcaaca
    10261 cgacgaagaa ggagatcccg accagcacgt attgcgtctt ctgccggtac cacgcggtca
    10321 gctgatcctc gaaggtcttg aaccagtcgt ccagcatgag ctggaacttc gccaggtcgc
    10381 cgttcgcgcg ggcgcagagg tcgatgaggg cgctccgcat cggcgcgttt gccggcagct
    10441 gctcggcaag cgcccgaatg tcgccgaccc gcgcgaaggc gtcctccttg aagccctgga
    10501 cctgcgagag aacgccctgc gtcaactgcc acgccgagac atagctcacc cggaaggtct
    10561 tccagacgcc gcgcgtaccc aggtgcgaca ggaagggcga gtcgagcacc tcgtccgccc
    10621 gctccgtgtc cagcgaccgc gggtccgccg agagcaggct cgcgatcccc ctgcgcagcc
    10681 agcgcgcgcg actgctcagc gcggcggcga tgaactcgtt gatcgacgtc accgcaagcg
    10741 cgaagaccag gtagatcagg gacaggccca gcagcacatc cagcgcgagc agaaaatcca
    10801 tgtcatcggt tcctgactgc aaagcccggc atccgtcgac cggtcaggcc agccctgctc
    10861 ccttgaggac cggcttccag cgttccttgg cgatcttctt gaagcccttg cccttcgggt
    10921 gcagctcgtt cgcccaatcc ttttccgcga gcgtgccccg gctgtcgacg atgagcagat
    10981 gggctggatc gcccgcagcg acacgcccga gcatggcgtg aaacgcatcg atgagatagc
    11041 gcacgcagtc gcgctgaagc gcctccggga cgcccgcatc gaccagcgcg ggcttgagcc
    11101 agccggcctt gcccgcgacg ccgcgaccat ccggaatcgc gtagtcgtac gaatgcatca
    11161 ggatgcgaca gtcgagcgag gtgtgggtgt agatcaggcc gatcaggcgc cggtaatgat
    11221 cgtccatgcg ctccaggaaa tgcccgagcc cgccgtcccc gctgcggaag cagtcggcag
    11281 ccgactgcgc gccgctgcag tccagcgcga gcaggggccg catgtcgttg aaccccgcga
    11341 agtcgttgcc gccgccgctg atgaacaccg ccgacaggct gtttccatat cgacgcagcg
    11401 caccggtgat ccggtccttg tacttgccat cgatgtagtc gaaggcctcg gcgccgttca
    11461 tgccgtacgc gaggatggtg tgctccttcc tctcgacgat cggccccaga tagcgaatca
    11521 ggctgccgcc ggggaagggg taccagaacc aggaatctcc gatcgccagg atactcggca
    11581 tcaccagcac ccgttgcatc gcggcttcat cccagtatgc ggccatgtcg cgcacctccc
    11641 gccaagatcc atccatcctc gccgggaagc agagtcgcac atcccgcccc ccatcggcgc
    11701 cacccgcttt caatcaagat gacgggaggg tctctgtcaa gagtcgcgga cggaagtccc
    11761 cgaggaatcc tgcggccatc gaagcgtggc ctggatccgc gcggacgcaa cgttggagcg
    11821 gctacttcgg gcgcggcaca tgccgagccg ccgctttcgc gcctgccggc gctcctacat
    11881 gaaccggcgc ggctcggagc gttgcggcga tcgacaccgc cccgcggctt gcatgaaccg
    11941 actccgccca tcgaggtgca cgaaccgacg cggcccggcg gcttgtagga gcggcggcag
    12001 ccgcgaattc ggcggtcgga tgttcgaccg ccgtgggatc tcatgcgccg cattcgcgcc
    12061 tgccggcgct cctacatgaa ccggcggggc tcgacgcgtt gcgggggatc gacgccgacc
    12121 ggctggttac atgaaccgac tccgtccggc gggttacatg aaccgactcc gtccggcggg
    12181 ttgtaggagc ggcggcagcc gcgaattcgg cagccggatc atcggcgcga atggaaggcc
    12241 tcaaccccgc ctcagccatc gcgcctcacc ctccgcctcg gccatccccg ccccagctgc
    12301 ccgacctcag ccgcagtgcc cgcccgagca acatcccccc gcggcgaccg gttgggcgag
    12361 cccggcccag cgcgcgagct cgttgcgggt gggatggcgg ccggcgacgg ccagttcgcc
    12421 gtcgaccagg gccagcggca gcgcgtcgta gccggagcgc tcgacgaagt cctcgacgac
    12481 cgcgttgcgg gcgaactcgt ccggctgctc ggcgaagctg aagcgctcga tgtgcgcgcc
    12541 ctgctccttc gcccacgcca cgtcggccgc gaaatcggcc gccgcctcgt ccgggaccgc
    12601 gccactgccg ccctgcgaaa gctcgaagat ctggatgttt ctcattttct gtctcctgca
    12661 ccccccaagc tggcggagtc gatgtaaagg tcgttcgctt cggccgcctg cggcgccgaa
    12721 gcaccgaatc taatcgcgca cggcatccct gccaagcggg tgaacctggg caatcgcatg
    12781 aaggcaccat gggagtgggg cttgcccgca acgagcaccg acagggaccc gttgcgcaga
    12841 caagcccgct accacgagcg ctgttcgagc cggccatccc gttcgtgcga tcgccccggc
    12901 gggtgggcga tatcagcccc cttctcgggt ggcccgacgg tcatcacatc ttcgccagtt
    12961 ctgcaatcag gtgcgctttg ccctccccaa gcgcagccag ctccgcctcg tcgatcaggc
    13021 ctcgacgcag cagccccgcg aacacgaaga ccaagaccga atagcggaaa tcgtaacgct
    13081 cgtcgagctc gcgccgcttc tgctcggcct cccgaagcag cgcccagagc gcgtcgggcg
    13141 tctcgatcgc ggcggcgctc gccttgaagc gggcgatgta gtccgtcatc tcgcgcccga
    13201 gcgcgacgtc gaacaagccc cgtgcggcct tcttctcggc ctgggtccat ttgagttcgt
    13261 gcatgccgac tcctgtcgtg atccggggct acactcacgc ccctgcccca ccaggggctt
    13321 cccgaaatcc gttgtggtga tggatctcga tcgtcgaatg gacgatctcc tcgtgcaccg
    13381 ccaggcgcgc acgcaccgcg tcgggcgtga gcgcgccgtc acgtgtaacc accgcgatgg
    13441 cgcacgagta ggcctccttg ccgacgcgcc agacgtgcag gtcgatgatc cgcgtgtcgt
    13501 ccgcctgcgg gccggattcg accacttcgc ggatttcggc gacgaccggg tggtccatct
    13561 cgcgatcgag cagcaccctg cccgtctcga ccagaaggcc cttcgcccac acggcgacca
    13621 gcaccgcacc gacgatgccc atcaccgggt cgagccagga ccagccgtag atccatccgc
    13681 ccacgagcgc gacgatggcc agcaccgagg tggccgcatc ggcgatgacg tggaggtaag
    13741 cggacttcaa gttgaggtcg tgatgggggt ggtcgtggcc gtgatggtga tcatgcccgt
    13801 ggtggtgcgc cttgcccagg atcagcgcgc acgcaaggtt gaccgccagg ccgaggatgg
    13861 cgaccgcgat tgcctcacgg tactggatgg cttgcggcga cacgatgcgc tcgatcgagc
    13921 cgaccaccat catcgccgcc acgccgagca ggaagatggc gctggcgaag ccgcccagga
    13981 tctcgatctt ccaggtgccg aaggcgaagc gccggtcctg cgcgtagcgc cgggcggcgg
    14041 cataggccag cgcggacagg ccgatcgcga aggcgtgcga actcatgtgc cagccgtcgg
    14101 cgagcagcgc catcgagttg aaccaccagc cggcggtgat ctcgatgacc atcgccgcag
    14161 cggtgatcca catcaccacc caggtgctgc gctcggcgag cgcgttgccc gtatcgaaga
    14221 cgtggtcgtg cgtccacgcg gacaggttgt cggtaggcat ggcaaggctc acttgaggta
    14281 ggtgcgcagg acgccgatca actcgtcggc gccctttgtg cgctcggcgg cgtcggtgat
    14341 cgccgggtcg gcgatgtggg tgcggacgtg ctcctcgagc acctcggcca tcagcccgtt
    14401 ggtggcgccg cgcaccgcag cgatctggtg caggatctcg gcgcattcct tcccggcctc
    14461 gagcgcgcgc tcgagcgcct cgacctggcc gcggatgcga cggacgcggg ccagcagctt
    14521 ggccttgtca cggatggtat ggctcacctg aacgcccccg ataagatagg ggggtatggt
    14581 atatgaagca gcgcacatcg gtcactccgg tagtgctcga atgcagatgc gatcgcccgg
    14641 aggcgctcgc ggacatcgac cgacttgaaa cgagtgattg cagcttcagc ccgcacgccg
    14701 gcgcgggcag tcggtgcgcg gctgcagtgt taatgccatt aacacagcac ctcctttcca
    14761 ttcacaaatc tccccccggc gttaacaccc gatgcctatg atcgggatgt ggtttttgta
    14821 ccggacgctt ccatgcccga gccgaccccg cgccgcgcgc gcatcgcatc gggccccgtc
    14881 cgggaaacgc atcgacgcgg agatcgagac atgaacaatc aagcaagcgg gcattccgcc
    14941 ccatcgggtg tgcaggcccc cgggcgtccg ggcgagtggc gcaggttcct gctgctcgcc
    15001 ttcatcggcc tgcccatcac catgacgctg gcgatcgcgg cctacggctt cgtggtctgg
    15061 ttcctgcaga tcctggtctt cggccctccg tcctgactcc tccacgcgca agcatcggcc
    15121 tcgcggcatg caccgcccgg cctggaatcg gacaacccgc aggagcactc aaatgacaaa
    15181 tctgcttcgg tccctcaggg acctcttcct caagcccgcc gtgcgtatcg gcctcggcgt
    15241 gctggtcacc ggcggcttca tcgccggcgt gctggcctgg cagggcttca acaccgccat
    15301 ggaagccacc aacaaggaag agttctgcct gagctgccac accatgcacg acaacctgct
    15361 gcccgagctg cagaagacgg tgcactggaa caaccgcacc ggcgtgcgcg cgcgctgccc
    15421 ggactgccac gtgccgcacg acttcaccga caaggtggcg cgcaagatgc aggcgagccg
    15481 cgaggtgctg ggccagctgc tgggcaccat cgacacccgt gagaagttca aggagcaccg
    15541 catcgtgctg gcgcagcgcg agtggaagcg cttctcggcc aacggctcga aggaatgccg
    15601 cgcctgccac gactacaagg acatggactt cgacaagatg cgtccggcct cgcaggtggc
    15661 gatgcgcaag gccgccgagc gcaaccagag ctgcgtcgat tgccacaagg gcgtcgccca
    15721 ccagctgccc gagatgaagg gcgcgcgcaa cccggccttc gacaccctgg tgtcctccgc
    15781 ggccggccag agcgtggatg ccggcaagga ctacttcctg gtggtgccgc aggagctcta
    15841 tgccgacgaa ggcatgacga agcgcatcgg cgcgatcgag gtggccaccc aggtaaaggt
    15901 gctcgagacc aagggcgacg cgcagcgcgt cgagctggcg ctgtggcgca agaacaaggg
    15961 ctacggccgc gtctggtaca gccacttcgg gctcaacatc accagcgccg tgctcgacaa
    16021 ggaggtggcg caggatgcga gcttcgtgaa ggtgctcgac acccgcgagg acccgatgac
    16081 cggcctcgaa tggcagcagg tcaccgccag cgcgtggatg cgcaagggca gcgtgctcga
    16141 cagcgtcgag ccggtgtggt cgatcgcccg cgccagctac agcagcagct gcagcgtgtg
    16201 ccaccgccag cccgaggaag cgcacttcga cgccaacacc tggcccggcc tcttcggcgg
    16261 catggtcggc ttcaccagca tggacgacga caccgcccgc gtggtgctca agtacccgca
    16321 gacccattcg tccgatttca gcacgtcgca cggcgccggt tcgcccgatt ccgccctgca
    16381 gaccgcgcgt ccctgatcag gagttgaaca ccatgaacta ctctcggcga ggtttcctca
    16441 aggccctggc gacgatgtcg ggcagcgcgc tggtcgcgcc cgccctgctc gccagccggt
    16501 ccgcgctggc ggccggcgag gcggccgcgg tcggcgacga catcaccacc tggaagatct
    16561 ccggctcgca cttcggcgcc atccgcgcca aggtggtcgg cgaccgcgtg gtcgacatcc
    16621 gccccttcga gctcgacaag cacccgacgg agatgatcaa gggtctgctc ggcctgatct
    16681 acagcccgtc ccgcgtgcgc tacccgatgg tgcgcctgga ctggtaccgc aagcgccacc
    16741 tcagcgacac cagccagcgc ggcgacaatc gcttcgtgcg ggtgagttgg gacgaggcgc
    16801 tcgacctgtt ctacgaagaa ctcgagcgca tccagaagga ctacggcccg tgggcgctgc
    16861 acaccggcgg cgtgggctgg cgctcggtcg gccaggtgca tagctgcggc aaccacatgg
    16921 tgcgcggcgt cggcatgcac ggccgcagcg tcggcaccat cggcgactac tcgaccggcg
    16981 ccgggcagat gatcctgccc tacgtgctcg gctcgaccga ggtgtattcg caaggcacct
    17041 cctgggacgt gatcctcaag gaaagcaagc tcgtcgtgtt ctgggccaac gacccggtca
    17101 agaacctgca ggtgggctgg aacaccgaga cccacgagtc ctacgcctac tttgaacaac
    17161 tcaagcaaaa ggtcgccgac aagtcgatcc aggcgatctg catcgacccg gtcaagagca
    17221 agacgctcga ctacctcggc ggcgccgagc accagtacat ccacccgatg accgatgtgc
    17281 cgctgatgct cgccatcgcg cacacgctgg tgaaggaagg cctgcacgac cagaagttcc
    17341 tcgacaccta cacgctgggc ttcgaccgct tcctgcccta cctgcagggc aagaccgagg
    17401 acatggtcga gaagacgccc gaatgggccg agcagatctg cggcgtgccc gccgagcgca
    17461 tccgcgagct cgcccgcctg atggccaggc atcgcaccca gctcatcttc ggctgggcgg
    17521 tgcagcgcca gcagcacggc gagcagccct actggatggg cgcggtgctc gccgccatgc
    17581 tcggccagat cggcctgccc ggcggcggca tcagctacgc gcaccactac agctcggtgg
    17641 gcgtatcctc gtcgggcgcg gccatgcccg gcgccttccc gctcaacctc gaccccggcc
    17701 gcaagcccag gcacgacaac accgacttca agggctacag cgcggtggtg ccgatcgcgc
    17761 gcgtcatcga cgccctgctc gagccgggca aggagatcga cttcaacggc ggcaaggtca
    17821 agctgccgcc ctacaagatg gcgatcttca gcggctgcaa ccagtggcac cgccagcccc
    17881 agcgcaaccg catgaaggaa gcctggcgca agctcgagac cgtggtcgcc atcgactaca
    17941 actggaccgc gacctgccgc ttcgccgaca tcgtgctgcc ggcgtgcacc cccttcgagc
    18001 gcaacgacct cgacggctac ggctcgtaca gcaaccgcgg catcatcgcg atgcaaaagc
    18061 tcatcgaccc gctcttccac tcgcgccccg acttcgagat cttccgcggc ctcacccggc
    18121 gcttcaaccg cgacgccgaa tacacccgcg gcatggacga gatgcagtgg gtcgagaaga
    18181 tctacgagga ctgccgcaag gagaacggcc tcaaggacat cgccatgccg ccgttcgccg
    18241 agttctggca gaagggctac gtgatgttcc ccgagggcaa gccctgggtg cgccacgccg
    18301 acttccgcga cgacgccgag gtcaacgcgc tcggcacgcc ctcgggcttc atcgagatct
    18361 tcagccgcaa gatcgagcgc tacggctacg ccgactgcaa gggccacccg gtgtggatgg
    18421 agaagaccga gcgctcgcac ggcggccccg gctccgaccg cttcccgctg tggctgcagt
    18481 cggtgcaccc ggacaagcgc ctgcactcgc agctgtgcga atccgagccg ctgcgcgaga
    18541 cctacgccat cgccgggcgc gagccggtct tcatcggccc cgaggacgcc gccgcgcgcg
    18601 gcatccagca cggtgacctg gtgcgcgtct tcaacgaccg cggccagttg ctggccggcg
    18661 cgcacgtttc ggacaacttc ccgcgcggcg tggtgcgcat ccaggaaggc gcctggtacg
    18721 gaccgaccgg gccggagatc ggcgcgctcg acacctacgg cgaccccaac acgctgacgc
    18781 tggacatcgg cacctccagc ctcgcgcagg ccaccagcgc caacacctgc ctggtgcaga
    18841 tcgaaaaatt cgtcggcacc gcgccggcgg tgacgtcctt cggcggcccg atcgaggtcg
    18901 atccggaagg gcgggaggtg aaggcgtgat gagcaccgat acggacgaca ggcaaggtgc
    18961 agcggccgaa gccgcccccc gcgcgagcgc cgagacgcag tccgcggccg cgcccggggc
    19021 ggctcgggac gtcggcggct cagccgactc cgtgcccctc tctcacgaag agtggcagtt
    19081 cgccggcacg cagcgcgcgg ggctgtacgg ctggttcgcc cggctgtacg ccgaggaggt
    19141 ttccgagccg gtttatcgca gccacttcgc cgacgggggc ttcgccccct tcgcggggct
    19201 ggccgagctc agcctcgagg ccgaggtgca acgcctcgac gcggccatcg ccaccctgcg
    19261 cgccgagcag ctgccgcgcc tggagctggc cgccgacttc gcccagctct tcctgctcga
    19321 cggcaagacc agcgccctgc cctacgcctc ggcctacaca ggcaccgacg gcgcctcacc
    19381 gctcttcggc gcggccgagg cacgcatgcg cgacttcctc gccgcaagcg ggttgagcat
    19441 ccaggccgac ttccgcgaac ccgccgacca cctcgccgtg ccactggcgt tgatggcgga
    19501 gctggccggg gcggcgtcga gcgcagagga catccccacc gccgccgcgg cccaggcgga
    19561 cttcctgcgc accgccgtgc tcgactggct gccacgtttc gtcgagcgct gccagcaggc
    19621 gcgcccacgc ttcgacgtct atccggcgct ggcggccctg ctgcttgggt tcgtgcgcgc
    19681 ggacgtggcg tttctggagg atgtgggcgg gagtgcggca gtctcctgaa tcgcgccacc
    19741 ccagacaggg gcagcgatca cgccgcccgc tgccgcctgc gcgattccca cccgaggcag
    19801 gccaacccga ccaccttcgg aatcggccgg cttccggtgc ggtagtgcgc gatcatgcgc
    19861 ctggtcatgc cgagcgattc ggctgcgctc gcaagcgaca ggccattgcg ctgcatccag
    19921 tcgttgaact cgctggccgt cggcaggccg gcctgccggc gggacagttc gtacagccgg
    19981 tcggcgccca gacccagccc gtccggccaa tccagcccgt gcccccactc gtcacgcgtc
    20041 atgcgtgcga agaagtccgg ggtgcgcagc gcatcgaagg gcggctgggc gagatcggac
    20101 aggtcgaccg gcaaggtttc gcccgtgctc cagccgatct cgagcttcag atcgcccgtc
    20161 acacgggctg tttcgatgcg ggggggcgtc ttcatggatt gagcctccgg tattcgtcca
    20221 ggtacttcgc cttgtttgcg cggatgtccg ccagcgcggc gaccagccgc ttcagtggct
    20281 gcaccccgcc caccaacact tcgcccgtct cgatcgcaac cgacacacgg cttccatcgc
    20341 gagagatcac atgaacgtga ggaaccccat gctccatgcc gttgatgcgg atccgccagt
    20401 cgcccacgat gtcgtagttg gtcatcgcca gaatagtgaa atggttacac ttaatcaaga
    20461 gccgatcaaa ttgccatcag catatct
//
LOCUS       DAOTIN010000054        19656 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_3329_length_19656_cov_8.680322, whole genome shotgun sequence.
ACCESSION   DAOTIN010000054 DAOTIN010000000
VERSION     DAOTIN010000054.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 19656)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 19656)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19656
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3329_length_19656_cov_8.680322"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(37..1026)
                     /locus_tag="P5537_09655"
     CDS             complement(37..1026)
                     /locus_tag="P5537_09655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PQQ-dependent catabolism-associated
                     beta-propeller protein"
                     /protein_id="HRV78346.1"
                     /translation="MTRPTTPIRCLAAVLSLGLFAGAALAKDTGYLFVSSENDNAVTV
                     LDGKSFQVVKAIATGERPRDMKLSADRSQVFVIASNSERVDVIDIAKLEVVRSIDVGE
                     DPEMFDFAKDGGRIYVSNEEDAEVSVIDVVANKVLAKIEVGEEPEGVLVGKDGSRLYV
                     TSEVANMVHVIDTASNAILANVVVGNRPRRFADTPDGSEVWVTNELGASVTVLDAKAN
                     VVKETVTFAPKGFRSDDVTPVGITMTRDGKTAYVTLGRANHVAVVDVATRKVRDYVLV
                     GNRAWGATLSRDESMLVVVNGLSDDISLVDTKTNKVLRSVPVGRVPHTAVIDD"
     gene            complement(1104..1859)
                     /locus_tag="P5537_09660"
     CDS             complement(1104..1859)
                     /locus_tag="P5537_09660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV78347.1"
                     /translation="MTEARAVLLEARAVRKAYGARPALKGVDLAVHAGEFVALLGPNG
                     AGKSTLFQLLTGLFDADAGELRVCGEDMRRTPVRALGRIGVVFQQMTLDLDLSVEANL
                     VFHARLHGIGGAESRARIADVLARVGLAERRADRVRELSGGNRRKVELARALLHRPAV
                     LLMDEATVGLDPASRRHLLDEVLALRAAGVGVLWATHLVDEAEAADRVLVLHRGELLA
                     AGPPAGLTAAAQCASLSEAFLKLTGAPQASERE"
     gene            complement(1852..2619)
                     /locus_tag="P5537_09665"
     CDS             complement(1852..2619)
                     /locus_tag="P5537_09665"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV78348.1"
                     /translation="MLDIRIDTKRYPDRGGRPHLALSGLRMQVARGEFVCVVGPSGCG
                     KSTLLAIVGGLDRACAGEVSMDGAAPADLGFMFQEPRLMPWMSVLDNVLLVVPDGLRE
                     QARARAVELLRAMELGDVLDAYPGRLSGGMMRRVALARAFVNEPALLLMDEPFVSLDS
                     PTANRLRAMLVAQWQRCQASVLFVTHDLREALALADRICFLSPSPGRVVLEYTVDLPR
                     PRDPSGAQLEQLHAQLLARHPELLAGLPALRAEAAHD"
     gene            complement(2622..3479)
                     /locus_tag="P5537_09670"
     CDS             complement(2622..3479)
                     /locus_tag="P5537_09670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV78349.1"
                     /translation="MSAQRFAPPASAVPARPPVPSPTSPHEPAAAAAQGAPAWREERR
                     LRIASLLVFVLLWQLGASLADSRTLPDPLAVLARIGAETASLALPGHLAVTLGRVAVA
                     FAVAMLVGALVGMAMGRWRKVDAFLDAWLVLGLNIPALVTIILCYVWFGLNDWAAILA
                     VAINKIPTVVVTVREGARAVDPKLLEVARAYRLGRRTTFLRVYLPQLVPYLMAAARAG
                     LSLIWKIVLVVELLGRSEGVGFQLNVFFQFFDITGILAYTLVFAGVVLAAEGWVLRPL
                     ERRLGAWRA"
     gene            complement(3476..4465)
                     /locus_tag="P5537_09675"
     CDS             complement(3476..4465)
                     /locus_tag="P5537_09675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002944298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HRV78350.1"
                     /translation="MPQLFARLIGVVLLALAAGSAALAADRPVVRVGVLQFGTVSWEL
                     ETMQRHGLLEREGVDVRVVPLALKDAANVALQGGEVDVIVNDWLWVARMRSEGADFVF
                     VPFSQAVGGIHVRPDAGIAGFADLRGKRLGVAGGALDKSWLLLRAYARRTVGEDAASF
                     LRPQFAAPPLLNELVTRGELPAAMNFWHYGARLAAAGMPEVLGMKEILATLGIGDEMP
                     LVGWVFGERWAQANPAAVAGFLRASTAAKALLRESDAAWEALRPSMRVDDEASFAALR
                     EGFRAGIPKGAGEEGERAAARAFAILAAEGGEALVGRARELAPGTFWHGGGGR"
     gene            4848..5597
                     /locus_tag="P5537_09680"
     CDS             4848..5597
                     /locus_tag="P5537_09680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HRV78351.1"
                     /translation="MLGQHTDDAPHERRVAGVALDRERLLALSAPAMEDLHRQLDSPG
                     ITVLLADSAGGVLRAIGAQGGTLPAGARPPATPQADAPAAAAQSSPTTPASAALPPGQ
                     LGIAVPILPPAGALLGFLDADAAPVEWLGHANALLHTAACIIEHRLIETEPQGFLLLR
                     FHRYASVLGTPLEALVLFDAEGAVMLANHTARALLAPCAFSAGGAAACFATQWCGIVG
                     YAALGLRQPFVLRDRRGGGFSAQASLRRHAS"
     gene            5594..6991
                     /locus_tag="P5537_09685"
     CDS             5594..6991
                     /locus_tag="P5537_09685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HRV78352.1"
                     /translation="MNRARTPSLQARLSLVLTVLIAVLMGIGAAVWMRETRQAIHEEV
                     EAATRVAQQWLVVVLAERREGGAEAEARERLLGRLAAVGRIRANRLEVFAAGGQRLYV
                     SPESPYKAGRDAPAWFAAQIAPELGARRLDAGALEVVLTPDTSRAVLDAWDHLVAALG
                     WACALLLALWLATRLAIRRALAPLQQIHAALEHGASGRFDQRLPQYATRELALLARSY
                     NRLADSLDESRATNARLEADQNLARTIQARLEQERRAIARELHDELGQSITAVRSIAG
                     AILQRSAEQPGIHGSAQAILAMTGHMQDGVHAILQRLRRDAPAAHERIEDTLQAYCAL
                     WASHHEGIELRCAIEPLGDARDEPLDDGVGLALLRVLQESLTNVARHAHARTVEVRIG
                     LRREGVDRNGQAEIEVEVRDDGRGLGAQPTPGRHGLAGMRERLAELHGRLELLSPPDG
                     GLCVRARLPQPVPVT"
     gene            6994..7644
                     /locus_tag="P5537_09690"
     CDS             6994..7644
                     /locus_tag="P5537_09690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HRV78353.1"
                     /translation="MKPPSLHALRILLADDHAVVRMGFRLLLEGAGAEVVGEADCGEA
                     AVQAFGPLQPDLLLMDVSMPGIGGLGALERVLAHHPGARVLMLSAHDDAQIPARALRA
                     GAGGYLSKRAHPDELLHAVATVARGQRYIDPAIAPALALAQFAGGGDPVAALTEKEFA
                     VFLQLAQGRSVAEIAESHSLSPSTVGTHLYHIKQKLEVSNAAEIALVAVRCGLIEV"
     gene            7763..8443
                     /locus_tag="P5537_09695"
     CDS             7763..8443
                     /locus_tag="P5537_09695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase family protein"
                     /protein_id="HRV78354.1"
                     /translation="MRKETDPQDFLAPSYYFDFEHPRVRAFIEESLGDAVDPVERAVK
                     LYYAVRDGIRYDPYRFYMRREYFTASRTLIEGAAYCVPKANLLTAVARGAGIPARVGF
                     ADVRNHLSTERLRQLVGGDVYRWHGYVAMYLEGRWVKATPAFNLQMCERFDVHPLEFD
                     GRADSLMHPYNARDERHMEYVKERGTFDDFPFEALVADMWKHHPGLVEAAEADLKGDF
                     EHEAMVDR"
     gene            8553..10592
                     /locus_tag="P5537_09700"
     CDS             8553..10592
                     /locus_tag="P5537_09700"
                     /EC_number="3.1.3.1"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0004035 - alkaline phosphatase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase D family protein"
                     /protein_id="HRV78355.1"
                     /translation="MSAPTAATPNPVGHDSRGPDSTDLVLAGPILRRVEARRVVLWLA
                     STRPLRARIVLHPDGGGEIRPAGAADAAGRAQCRSLRAGDHLHYLLLDFALAAELPAS
                     RWIGYALELAPADDEAAPWLGWQDWAPDLCYPGRTLPGFVFAPRVAALLHGSCRKPHH
                     DGGDGLVRVDRLLAELIARGATDAEPVPGPDGLPGWPSALVLTGDQIYADDVAGPMLG
                     AIHALLDRLALPAERLEAAGETGVRDADALRRHPACYYRRETLLPRHKRNYALLEVLF
                     GGVEKPVFTSASAHNHLITLAEVLAMYLLVWSPAPWRELRVAPPPGLSEEDAALWKKE
                     QGLIEAFVAELPAVRRALAHVPVAMIFDDHDVTDDWNLSREWEEVAYGHPFSRRVIGN
                     AIVAYAINQAWGNRPDVFDDTLFEHLQRSLDAPGAQAHDDCIDALLRFEDWHYTWPTT
                     PPLVVIDTRTRRWRSERTARRPSGLMDWESLTDLQQVLRGLPAVLLVSPAPIFGVKLI
                     ETIQRIFTWFGHPLMVDAENWMAHPGSAQAILNIFRHRRTPRNFVVLSGDVHYSFVYD
                     VELRGRVRGPDIWQICSSGVRNEFPPRLLGVLDRLNRWMYSPRSPLNWFTRRRHMRVT
                     PRRYEGAARGRRLLGGAGIGLVELDAEGVPWRIRELLADGATIAFEREEDFSRWA"
     gene            complement(10633..11175)
                     /locus_tag="P5537_09705"
     CDS             complement(10633..11175)
                     /locus_tag="P5537_09705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78356.1"
                     /translation="MPVQLLLAMLRNPASTGAVMPSSRTLANAMAGAAVGADTVVELG
                     AGTGPVTEALLRRLPGVPLIAVELQPALARRLQARFPTVDVRQAAAKEVVDGLIERPG
                     RVVLVSSLPFRSLPREVAAETVDSLCRFLAHDGERKLVQFTYQPRAPFAVPRQLRWHR
                     RAVVWRNTPPAGVWELQAVR"
     gene            11382..12293
                     /locus_tag="P5537_09710"
     CDS             11382..12293
                     /locus_tag="P5537_09710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF808 domain-containing protein"
                     /protein_id="HRV78357.1"
                     /translation="MAGTTLLALIDDIATIMDDVATMTKVAAKKTAGVLGDDLALNAQ
                     QVTGVQASRELPVVWAVAKGSLVNKAILVPAALLISWLAPWLITPLLMLGGAFLCFEG
                     FEKLAHKFLHSKAEDEVEHRETLQAVADPNVDLVAFEKEKIKGAVRTDFILSAEIVVI
                     TLGTVAAASLGQRVAVLVGISLLMTVGVYGLVAGIVKLDDLGLHLQRSTSAFTRRIGG
                     AILGFAPWLMKTLSVVGTAAMFMVGGGILLHGWPTAAHAVEHFAEGFGGVGGALINTG
                     AGAGVGILAGAVVLAGVMLVQKLRGAH"
     gene            complement(12383..13174)
                     /gene="pqqC"
                     /locus_tag="P5537_09715"
     CDS             complement(12383..13174)
                     /gene="pqqC"
                     /locus_tag="P5537_09715"
                     /EC_number="1.3.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroloquinoline-quinone synthase PqqC"
                     /protein_id="HRV78358.1"
                     /translation="MSYIDQTSIEHTAALAARADDLPPWSPAEFEALLREKGTSYHIH
                     HPFHVMMAEGKLTREQLQGWVANRFYYQISIPVKDAAILSNCPERAIRREWIQRILDH
                     DGFEIGDVKDPGGIEAWIRLGEATGLSRDDVTSLRFVAPATRFAVDAYIDFARRRPWQ
                     EAVASSLTELFAPHIHQQRLDTWPTHYPWVDAAGLQYFRNRLTQARRDVEHGLRFTLE
                     YFSRSRAMQQRALDILQFKLDVLWAMADAIMLSQCEVAIRGPRRC"
     gene            complement(13171..14085)
                     /gene="pqqB"
                     /locus_tag="P5537_09720"
     CDS             complement(13171..14085)
                     /gene="pqqB"
                     /locus_tag="P5537_09720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004248598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqB"
                     /protein_id="HRV78359.1"
                     /translation="MKIRVLGSAAGGGFPQWNCNCPNCDGLRKGRIRAQARTQSSIAA
                     SGDDENWVLFNASPDVLQQIRSFPALQPARALRDTGIAAIVLIDAQIDHTTGLYMLRE
                     HREPWPVWCTACVREDLSVGNPVFGVLGHYSGVDWRELPLQVRFAIDGAPGLGLEALV
                     LTSNAPPYSPHRDRPQPGDNIGVTLVDAASGKRLFYAPGLGEMEPQLWAAMQAADCVL
                     VDGTLWTDDEMIRLGASPKTSRAMGHLPQSGPGGMLEWLDKLPATTRKVLIHINNTNP
                     ILDEDSRERAELAAHGIEVAFDGMEIAL"
     gene            complement(14320..14922)
                     /locus_tag="P5537_09725"
     CDS             complement(14320..14922)
                     /locus_tag="P5537_09725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002931419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolysaccharide biosynthesis protein"
                     /protein_id="HRV78360.1"
                     /translation="MERIAGAHLASMDGTMAEALGQSNRQRLVWLSLLAMPLLFPVAL
                     PGMASVVGGFCLLIAFGLCVGQPVPLPRWLARREIDGRARALLQRMFGRVVGIVASLG
                     RPRLLRLSDRPARVLNASMLSIAGLSMMTPVPIISFDNVLPALAIVLISWGLRLRDGL
                     MLLVGYLVTLVAAASVLLLWWGGSAAVAELFALAGLAWGR"
     gene            15256..16287
                     /locus_tag="P5537_09730"
     CDS             15256..16287
                     /locus_tag="P5537_09730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HRV78361.1"
                     /translation="MSDAFQPASIGADGTRRAAMPVPRLDPESALLFVINAAAGALDV
                     DAKRAVIESTLAARGRRGELLVCAPDELARVATEAAAAALARNTAVVAVGGDGSLGTV
                     AQAAHAAGCPMGVIPYGTFNYFARTHGIPTEPAAAMRQVLDAHPRPVQVGAINDRVFL
                     VNASLGVYPELLQDREAYKARFGRSRWVAFVAGCATLLRAQRRLRLHIEMGSTVRDVQ
                     TLTLFVGNNRLQLQQLGAEPADTVAGTPGDGCLAALMLRPIGTLSMLGLMLRGAMGRL
                     GEAAGVEGFEFTHMAVKPRLARGRREVMVAFDGEVARMRAPIHIGVLDKPLYLLQVLG
                     RANSPAAGA"
     gene            16298..17131
                     /locus_tag="P5537_09735"
     CDS             16298..17131
                     /locus_tag="P5537_09735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002931414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HRV78362.1"
                     /translation="MSVLLHIADTHFGTERRSVVEALVALAAQQRPDLVVLAGDVTQR
                     ARPGQFRAAKAFVDRLGAPVLAVPGNHDIALFDPWARLTRPYARWAGAFGADLEPVHA
                     SAELLVVGVNTTRAWRHKNGEVSAAQIDRVAGLLATASPQQLRVVVVHQPAAVIRSRD
                     RANLLRGHQAALQAWSVAGADLVLGGHIHLPYTLAPPGLARRLWVLQAGTAVSSRTRA
                     EVPNSVNIVRWNEPSGAHDAPAQQGSAAGGSCLIEQWDFVRRDGCFVRKAVTPVQPER
                     S"
     gene            17356..19566
                     /locus_tag="P5537_09740"
     CDS             17356..19566
                     /locus_tag="P5537_09740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004306497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HRV78363.1"
                     /translation="MKAEQRAIPTAPTLPVASHEPPRAKKLAALLRLGVPGALAGFAC
                     LAGAQPADPGAVALNPVVVTGAPAATESFELPYSVDSVDMRANQAGNLGVNASEALAG
                     VPGLVIQNRQNYAQDLQISVRGFGARAAFGVRGVKLIADGIPATNPDGQGQAATFNLD
                     TAERIEVMRGPFATVYGNHAGGVIQLFSRKGEGDPRVRASVLGGSWGTTKFGIGAEGE
                     KNGVGFVLDASRFDTDGYRDHSKTRRDQGFAKLTLNPDEDSTLTLVANGLRQPETEDP
                     LGVTWETYERDPQSLTIDPLDPATPKRSYAARYNTRKSIHHVQGGATYERRLGEDRLQ
                     LSAYAGRRAVTQYQSFSKGFQSSPRHAGGVVDFDRDFHGMGLRWISQRTMGSGELTLT
                     AGIDYDHSEDDRRGYENFVGSTLGVKGRLRRDELDTITSIDPYVQALWKSGPWQWSLG
                     ARHSRVSFKVEDRYINTDNPDDSGSVRFSKTTPALGVSYALSPATNLYASVGAGYETP
                     TLNELSYATPTTGFNFGLRPSTSRQAEIGIKTFVGDDARINAALFRIETDDEIVVLAS
                     EEGRTSYQNAGRTLRQGIEIAAQAELTRTLTARASLTWMQAEYDEAFKSRGTTVAAGN
                     RIPGVPRIAAFAELAWQAAPGVTLAGEVLHRGEVEVNDLNNDRSAPAYTLFNLRLSAE
                     QQQGPWTFGQLLRVDNVLDRKYVGSVIVGDSNKRYYEPGPERSVYAGVSASYRF"
BASE COUNT         2871 a         7218 c         6895 g         2672 t
ORIGIN      
        1 gtttatgtag gagcgccggc aggcgcgaaa gcggcctcaa tcgtcgatca ccgcggtgtg
       61 gggcacgcgg ccgaccggca ccgagcgcag caccttgttg gtcttcgtgt cgaccagcga
      121 gatgtcgtcc gacaggccat tgaccaccac cagcatcgac tcgtcacggc tcagcgtcgc
      181 gccccaggcg cggttgccca ccagcacgta gtcacgcacc ttacgggtgg cgacgtccac
      241 caccgccacg tggttggcgc ggcccagcgt gacgtaggcc gtcttgccgt cgcgcgtcat
      301 ggtgatgccg accggcgtca cgtcgtcgct gcggaagccc ttgggcgcga acgtcaccgt
      361 ctccttcacc acgttggcct tcgcgtcgag caccgtcacc gaggcgccga gctcgttggt
      421 cacccacacc tcgctgccgt cgggcgtgtc ggcgaagcgg cgcgggcggt tgccgaccac
      481 cacgttggcg aggatcgcgt tgctggcggt gtcgatcaca tgaaccatgt tggccacctc
      541 cgaggtcacg tagagccggc tgccgtcctt gccgacgagc acgccctcgg gctcctcgcc
      601 cacctcgatc ttcgccagca ccttgttggc gacgacgtcg atcaccgaga cctcggcgtc
      661 ctcctcgttg gagacgtaga tgcggccgcc atccttggcg aagtcgaaca tctccgggtc
      721 ctcgccgacg tcgatgctgc gcacgacctc cagcttggcg atgtcgatca cgtccacgcg
      781 ctcgctgttg ctggcgatca cgaagacctg gctgcggtcg gccgagagct tcatgtcgcg
      841 cgggcgctcg ccggtggcga tggccttgac gacctggaag ctcttgccgt cgagcacggt
      901 caccgcgttg tcgttctcgc tgctgacgaa caggtagccg gtgtccttgg cgagcgcggc
      961 acctgcgaac aggccgaggc tcagcaccgc ggcgaggcag cggatcgggg tcgtgggtcg
     1021 ggtcatgcgg gtcgtctcct ggttgtaatg gccgcagggt gtggtcgcag cggcctcttg
     1081 cggcggaatg ccggttgtct aaatcattcg cgttcggacg cctgcggcgc gccggtgagt
     1141 ttcaggaagg cctcggacag gctggcgcac tgcgcggcgg cggtcaggcc ggcgggcggg
     1201 ccggccgcaa gcagctcgcc gcgatgcagc accagcacgc ggtcggccgc ctcggcctcg
     1261 tcgaccagat gggtggccca cagcacgccg acgcccgcag cgcgcagcgc cagcacctcg
     1321 tcgagcagat ggcggcgcga ggccgggtcg aggccgaccg tggcctcatc catcagcagc
     1381 accgccggcc ggtgcagcag cgcacgcgcg agctcgacct tgcgccggtt gccgccggag
     1441 agctcgcgca cgcggtcggc gcggcgctcg gcgaggccga cgcgcgcgag cacgtcggcg
     1501 atgcgcgcgc gcgactcggc accgccgatg ccgtgcaggc gcgcatggaa gacgaggttg
     1561 gcctccacgc tgaggtcgag gtccagcgtc atctgctgga acaccacgcc gatgcgcccg
     1621 agcgcgcgca ccggcgtgcg ccgcatgtcc tcgccgcaca cccgcagctc gccagcgtcg
     1681 gcgtcgaaca ggccggtcag caactggaag agcgtgctct tgccggcgcc gttgggcccg
     1741 agcagggcga cgaactcgcc cgcatgcacc gccaggtcca cccccttcag ggccggacgc
     1801 gcgccgtagg ccttgcgcac cgcgcgcgcc tcgagcagca ccgcgcgcgc ctcagtcatg
     1861 ggcggcctcc gcgcgcagcg ccggcaggcc ggcgagcagc tcggggtggc gggcgagcag
     1921 ctgcgcatgc agctgctcga gctgcgcacc ggaaggatcg cgcgggcgcg gcagatcgac
     1981 cgtgtactcg agcaccaccc gccccggcga gggcgacagg aagcagatgc ggtccgcgag
     2041 cgcgagcgcc tcgcgcaggt catgggtgac gaagagcacg ctcgcctggc agcgctgcca
     2101 ctgcgccacc agcatcgcgc gcaggcggtt ggcggtcggg ctgtcgagcg acacgaaggg
     2161 ctcgtccatc agcagcagtg cgggttcgtt gacgaaggcg cgggcgagcg cgacgcggcg
     2221 catcatgccg cccgagagcc gcccggggta ggcgtcgagc acgtcgccga gctccatcgc
     2281 gcgcagcaac tccaccgccc gcgcccgcgc ctgctcgcgc aggccgtcgg gcaccaccag
     2341 cagcacgttg tcgagcacgc tcatccacgg catcaggcgc ggctcctgga acatgaagcc
     2401 gaggtcggcc ggcgcggcgc cgtccatgct cacctcgccc gcacaggcgc gatcgagccc
     2461 gccgacgatg gcgagcagcg tgctcttgcc gcagcccgag ggccccacca cgcagacgaa
     2521 ctcgccgcgc gcgacctgca tgcgcagtcc ggacaaggcc aggtgcggcc gcccgccgcg
     2581 gtcggggtag cgcttggtgt cgatgcggat gtcgagcatg ttcacgccct ccaggcgccg
     2641 agccggcgct cgagcggacg cagcacccag ccctcggcgg ccagcaccac gccggcgaag
     2701 accagggtgt aggcgaggat gccggtgatg tcgaagaact ggaagaagac gttgagctgg
     2761 aagcccacgc cctcgctgcg cccgagcagc tcgaccacca gcacgatctt ccagatcagc
     2821 gacaggcccg cgcgcgccgc cgccatcagg tagggcacga gctgcggcag atacacgcgc
     2881 aggaaggtcg tacgccggcc caggcggtag gcgcgcgcga cctcgagcag cttggggtcg
     2941 accgcgcgcg caccctcgcg cacggtgacg acgacggtgg ggatcttgtt gatcgccacc
     3001 gcgaggatgg ccgcccagtc gttgaggccg aaccatacgt agcacaggat gatggtgacc
     3061 agcgccggga tgttgaggcc gagtaccagc caggcgtcga ggaaggcgtc caccttgcgc
     3121 cagcgcccca tcgccatgcc gaccagcgcg cccaccagca tcgccaccgc gaaggcgacc
     3181 gcgacccggc cgagggtcac ggcgaggtgc ccgggcaggg cgagcgaggc ggtctcggcg
     3241 ccgatgcgcg ccagcacggc gaggggatcg ggcagcgtgc ggctgtcggc gaggcttgcg
     3301 ccgagctgcc agagcagcac gaacacgagc agcgaggcga tgcgcagccg gcgttcctcg
     3361 cgccaggcgg gtgcgccctg cgccgcggcg gcggccggct cgtgcgggga ggtcggcgac
     3421 ggcaccgggg gacgcgcggg cacggcggat gcgggcgggg cgaagcgctg tgcgctcacc
     3481 gcccgccgcc cccatgccag aacgtgcccg gcgcgagctc gcgggcgcgc cccaccagcg
     3541 cctcgccgcc ctcggccgcg aggatcgcga aggcgcgcgc tgcggcgcgc tcgccctcct
     3601 cgcccgcccc cttcgggatg ccggcgcgga agccctcgcg cagcgcggcg aagctcgcct
     3661 cgtcgtcgac gcgcatcgac gggcgcaacg cctcccaggc ggcgtcggac tcgcgcagca
     3721 gcgccttggc cgcggtcgag gcgcgcagga agcccgccac cgccgccggg ttggcctgcg
     3781 cccagcgctc gccgaacacc cagcccacca gcggcatctc gtcgccgatg ccgagggtgg
     3841 cgaggatctc cttcatgccc agcacctcgg gcatgccggc ggcggcgagg cgcgcgccgt
     3901 agtgccagaa gttcatcgcc gcgggcagct cgccgcgcgt caccagctcg ttgagcagcg
     3961 gtggcgcggc gaactgcgga cgcaggaagc tcgcggcgtc ctcgccgacg gtgcggcggg
     4021 cataggcgcg cagcagcagc cagctcttgt cgagcgcacc gccagccacc ccgaggcgct
     4081 tgccgcgcag gtcggcaaag ccggcgatgc cggcatccgg gcgcacgtgg atgccgccga
     4141 ccgcctgcga gaagggtacg aagacgaaat ccgcgccctc cgagcgcatg cgtgccaccc
     4201 acagccagtc gttgacgatg acatcgacct cgccgccctg gagagcgacg ttggccgcgt
     4261 ccttgagcgc gagcggcacg acgcggacgt ccacgccctc gcgctcgagc aggccgtggc
     4321 gctgcatggt ctcgagctcc cagctcaccg tgccgaactg cagcacgccg acccgcacca
     4381 cgggccggtc ggcggcgagc gcggcgctgc ccgcggcgag cgccagcagg acgacgccga
     4441 tcaggcgggc aaagagctgg ggcatggggt ctcctccgtg gtggtgcgcg accaggcgaa
     4501 cgggcgcatg tttgttgtat gcgtctccca gcaggttccg tgccagcgct cgagatcccc
     4561 ctgtcgggca tacggctgcc cgcggcgtga cagggctggc gcagcggcga ctgttccgtt
     4621 tgggagcaac tctgctcagg gacgcaacaa cggcgcgccg acggccccgt gcaggcaggc
     4681 cccaccgcgg gcggaacccc ctcgtcatcc tcggcacgaa tcctgcatgg gcgaggacgg
     4741 gcggctttgt ccgcagcgac tccaggatca ccacagcgat gtccagtctt cccactcccg
     4801 cagcctccgc agttcccgct cccacgcggg gggcaccgac cacgctcatg ctcgggcagc
     4861 acaccgacga tgcgccgcac gagcgccgcg tcgccggcgt ggcgctcgac cgcgagcgcc
     4921 tgctcgcgct gtccgcaccc gcgatggagg atctccaccg ccagctcgac agccccggca
     4981 tcaccgtgct gctcgccgac agcgccggcg gcgtgctgcg cgcgatcggc gcgcaaggcg
     5041 gcacgctgcc cgcaggcgca cggccgcccg ccacgccgca ggccgacgcc ccggcggccg
     5101 cggcccagtc ctctcccacc acccctgcca gcgccgcgct gccgcccggc cagctcggca
     5161 tcgcggtgcc gatcctgccg ccggccggcg ccctgctcgg cttcctcgac gccgacgcgg
     5221 ctccggtgga atggctgggc cacgccaacg cgctgctcca caccgccgcc tgcatcatcg
     5281 agcaccgcct catcgagacc gagccgcagg gcttcctgct gctccgcttc caccgctacg
     5341 cgagcgtgct cggcaccccg ctcgaggcgc tggtcttgtt cgatgccgaa ggcgcggtca
     5401 tgctcgccaa ccacaccgca cgcgccctcc tcgccccctg cgccttcagc gcgggcggcg
     5461 ccgctgcctg cttcgccacc cagtggtgcg ggatcgtcgg ctatgccgcg ctcggcctgc
     5521 gccagccctt cgtgctgcgc gaccgccgcg gcggcggctt ctccgcgcag gccagcctgc
     5581 gccggcacgc atcatgaatc gcgcgcgcac gcccagcctg caggcccgcc tgagcctggt
     5641 gctcaccgtg ctgatcgcgg tgctgatggg gatcggcgcg gcagtgtgga tgcgcgagac
     5701 gcgccaggcc atccacgagg aggtcgaggc cgcgacccgg gtcgcgcagc aatggctcgt
     5761 cgtcgtgctt gcggagcggc gcgagggtgg ggccgaggcc gaggcgcgcg agcgcctgct
     5821 gggtcgcctc gccgcggtcg ggcgcatccg cgccaaccgg ctcgaggtct tcgctgcggg
     5881 cgggcagcgg ctctacgttt cgcccgagtc gccctacaag gcgggccgcg atgcaccggc
     5941 ctggttcgcg gcgcagatcg cgcccgaact cggcgcgcgc cggctcgacg ccggcgccct
     6001 ggaagtcgta ctgacgcccg acacctcgcg tgcggtgctc gacgcctggg accacctcgt
     6061 cgccgcgctc ggctgggcgt gcgcgctgct gctcgcgctg tggctcgcca cccgcctggc
     6121 gatccggcgc gcgctcgcgc cgctgcagca gatccacgcc gcgctcgaac atggcgccag
     6181 cgggcgcttc gaccagcgcc tgccgcaata cgccacgcgc gagctcgcgc tgctggcgcg
     6241 cagctacaac cgcctcgccg acagtctcga cgagtcgcgc gcgaccaacg cccgcctgga
     6301 agcggatcag aacctcgcgc gcacgatcca ggcccggctc gagcaggagc ggcgcgcgat
     6361 cgcgcgcgag ctgcacgacg agctcggcca gagcatcacc gccgtgcgct cgatcgccgg
     6421 cgccatcctg cagcgcagcg ccgaacagcc cggcatccac ggcagcgcgc aggccatcct
     6481 cgccatgacc ggccacatgc aggacggcgt gcacgcgatc ctgcagcgcc tgcgccgcga
     6541 cgcgccggcc gcgcacgagc gcatcgagga caccctgcag gcctactgcg cgctgtgggc
     6601 cagccatcac gaaggcatcg agctgcgctg cgcgatcgag cccctgggcg acgctcgcga
     6661 cgagccactc gacgacggcg tcggcctcgc cctgctgcgc gtgctgcagg agagcctgac
     6721 caacgtcgcc cgccacgccc atgcgcgcac ggtcgaggtc cgcatcggcc tgcgccgtga
     6781 aggcgtcgat cgcaacgggc aggcggagat cgaggtcgag gtgcgcgacg acggccgcgg
     6841 cctgggcgcg cagcccactc ccggccgcca cggcctcgcc ggcatgcgcg agcgcctcgc
     6901 cgaactccac ggtcgactcg aactgctcag cccgcccgac ggcggcctgt gcgtgcgcgc
     6961 ccgcctcccc caacccgtcc cggtcacgtg atcatgaaac cgccttccct ccacgccctg
     7021 cgcatcctgc tcgccgacga ccacgcggtg gtgcgcatgg gctttcgcct gctgctcgaa
     7081 ggcgccggtg ccgaagtcgt cggcgaggcc gactgcggcg aggcagccgt gcaggccttc
     7141 ggtccgctgc aacccgacct gctgctgatg gacgtgtcga tgccgggcat cggcgggctc
     7201 ggcgcgctcg aacgcgtgct cgcccaccac cccggtgcgc gcgtgctgat gctgtcggcg
     7261 cacgacgacg cgcagatccc cgcgcgcgcg ctgcgcgccg gtgcgggcgg ctacctgtcc
     7321 aagcgcgccc atccggacga gctgctgcat gcggtggcca cggtcgcgcg cggccagcgc
     7381 tacatcgacc cggcgatcgc gcccgccctc gcgctcgcgc agtttgccgg cggcggcgat
     7441 cccgtcgccg cgctcaccga gaaggagttc gccgtcttcc tgcagctcgc gcaagggcgc
     7501 agcgtggccg agatcgccga gagccacagc ctgagcccga gcacggtggg cacccacctc
     7561 taccacatca agcagaagct cgaggtctcc aacgccgccg agatcgcgct cgtcgcggtg
     7621 cgctgcgggc tcatcgaagt gtagccgcag gcgagtcggc cccctgttgc tgaagtccct
     7681 tcgcgcgaat tttgttgacg cgcacgtcaa cttcccctga tacactcccg tgaccacaag
     7741 gacacaccga ggaggagcgg gaatgcgcaa ggagacggat ccgcaggact ttctggcacc
     7801 aagttattac ttcgacttcg agcacccgcg cgtgcgcgcc ttcatcgagg agagcctggg
     7861 cgacgcggtc gaccccgtcg agcgcgccgt gaagctgtac tacgcggtgc gcgacggcat
     7921 ccgctacgac ccctatcgct tctacatgcg cagggagtac ttcaccgcca gccgcaccct
     7981 catcgagggc gccgcctact gcgtgcccaa ggccaacctg ctcaccgcgg tcgcgcgcgg
     8041 cgccggcatc ccggcgcgcg tgggcttcgc cgacgtgcgc aaccacctga gcaccgagcg
     8101 cctgcgccag ctggtcggcg gcgacgtgta ccgctggcac ggctacgtcg cgatgtacct
     8161 cgagggccgc tgggtaaagg cgacgccggc cttcaacctg cagatgtgcg agcgcttcga
     8221 cgtccacccg ctcgagttcg acggccgcgc cgactcgctg atgcacccct acaacgcgcg
     8281 cgacgaacgc cacatggagt acgtgaagga gcgcgggacc ttcgacgact tccccttcga
     8341 ggcgctcgtc gccgacatgt ggaagcacca cccgggcctg gtcgaggcgg ccgaggccga
     8401 cctgaagggc gacttcgagc acgaagcgat ggtcgaccgc tgagcgggcg cgagcggcac
     8461 cgcggcgggc gcgccacggt tttgcgggtg acgcattcgg cgccgctttg atataaagcg
     8521 gacatgaaat acgcatcccg ttcggacggc cgatgagcgc gcccacagcc gcgactccca
     8581 accccgtggg ccacgactcc aggggccccg actccaccga cctcgtcctc gccggcccca
     8641 tcctgcgccg ggtcgaggcg cgccgggtcg tgctctggct cgccagcacc cgcccgctgc
     8701 gcgcgcgcat cgtcctgcac ccggacggcg gcggcgagat ccgccccgcc ggcgctgccg
     8761 acgccgccgg gcgcgcgcaa tgccgcagcc tgcgcgccgg cgaccacctg cactacctgc
     8821 tgctcgactt cgcgctcgcg gccgagctgc ccgccagccg ctggatcggc tacgcgctcg
     8881 agctcgcccc cgccgacgac gaggccgcgc cctggctggg ctggcaggac tgggcacccg
     8941 acctgtgcta tccggggcgc acgctccccg gcttcgtgtt cgcgccgcgc gtcgctgcgc
     9001 tactgcacgg ctcctgccgc aagccgcacc acgacggcgg cgacggcctc gtgcgcgtcg
     9061 accgcctgct cgccgagctg attgcgcgcg gcgccaccga cgccgagccg gtgcccggcc
     9121 ccgacggcct gcccggctgg ccctcggcgc tcgtgctgac cggcgaccag atctacgccg
     9181 acgacgtcgc cggccccatg ctgggcgcga tccacgccct gctcgaccgc ctcgccctgc
     9241 ccgccgagcg cctcgaggcc gcaggcgaga ccggagtccg cgacgccgac gcgctgcgcc
     9301 gccaccccgc ctgctactac cggcgcgaga ccctgctgcc ccggcacaag cgcaactacg
     9361 ccctgctcga ggtcctcttc ggcggcgtgg agaagccggt gttcacctcg gcgagcgcac
     9421 acaaccacct gatcacgctc gccgaggtgc tggcgatgta cctgctggtg tggtcgcccg
     9481 cgccctggag ggagctgcgc gtggcgccgc cgccgggcct ctccgaggaa gacgccgcgt
     9541 tgtggaagaa ggagcagggc ctgatcgagg ccttcgtcgc cgagctgccg gcggtgcggc
     9601 gcgcgctcgc gcatgtgccg gtggcgatga tcttcgacga ccacgacgtc accgacgact
     9661 ggaacctgag ccgcgaatgg gaggaggtcg cctacggcca ccccttctcg cgccgggtga
     9721 tcggcaacgc gatcgtggcc tacgcgatca accaggcctg gggcaaccgc cccgacgtct
     9781 tcgacgacac gctcttcgag catctgcagc gcagcctgga cgcgcccggc gcgcaggcgc
     9841 acgacgactg catcgacgcc ctgctgcgct tcgaggactg gcactacacc tggccgacca
     9901 ccccgccgct ggtggtcatc gacacccgca cccggcgctg gcgctcggag cgcaccgcgc
     9961 gccgcccctc cgggctgatg gactgggagt cgctcaccga cctgcagcag gtgctgcgcg
    10021 gcctgcccgc ggtgctgctg gtgtcgccgg cgccgatctt cggcgtcaag ctgatcgaga
    10081 ccatccagcg catcttcacc tggttcggcc acccgctgat ggtggatgcg gagaactgga
    10141 tggcgcaccc gggctcggcg caggccatcc tcaacatctt ccgccaccgc cgcacgccgc
    10201 ggaacttcgt cgtgctctcg ggcgacgtgc attactcctt cgtctacgac gtcgagctgc
    10261 gcggccgcgt gcgcgggccg gacatctggc agatctgcag cagcggcgtg cgcaacgagt
    10321 tcccgccgcg gctgctcggg gtgctcgacc gcctcaaccg ctggatgtat tcgccgcgct
    10381 cgccgctcaa ctggttcacc cgccgccgcc acatgcgcgt gaccccgcgc cgctacgagg
    10441 gcgccgcgcg cggccgccgc ctgctcggcg gcgccggcat cggcctggtg gaactcgacg
    10501 ccgagggcgt gccctggcgc atccgcgagt tgctcgccga cggagcgacg atcgccttcg
    10561 agcgcgagga ggacttctcg cgctgggcat gaacgccacg gcgcccgcgg ccgcccggcg
    10621 gccgcgccgg cctcagcgca ccgcctgcag ctcccacacc ccggccggcg gcgtgttgcg
    10681 ccacaccacc gcgcgccgat gccagcgcag ctggcgcggc acggcgaagg gcgcgcgtgg
    10741 ctggtaggtg aactgcacga gcttgcgctc gccgtcgtgg gcgaggaatc ggcagaggct
    10801 atcgaccgtc tcggccgcga cctccctggg cagcgagcgg aaaggcaggc tggacaccag
    10861 caccacgcgc cccgggcgct cgatgaggcc gtcgacgacc tccttcgccg ccgcctggcg
    10921 cacatccacc gtgggaaagc gcgcctgcag ccgccgcgcc agcgcgggct ggagctcgac
    10981 cgcgatcagc ggcacgccgg gcaggcgacg cagcaaggcc tcggtgaccg ggccggtgcc
    11041 ggcgccgagc tcgaccacgg tgtcggcacc taccgccgcg cccgccatcg cattggccag
    11101 cgtgcgcgac gatggcatca ccgcgccggt ggatgcgggg ttgcgcagca tggccaacag
    11161 cagttgcacc ggcatgggcg ctcgtccctt cgagatcgac aggtgcccat ggtaacgccg
    11221 cgaccaccgc ccgcgcaccc cgaaattgct ccgcgaaatt gttccggaat acgccgcgcg
    11281 gcaacgcgcg caccgggtcg ggcgacgcca tggccacggg gcgcggctgc gggcgccggt
    11341 tttctgtcac catcacgcct ttgccttcac accctcacat catggctgga accaccctgc
    11401 tcgcactgat cgacgacatc gccaccatca tggacgacgt cgccaccatg accaaggtcg
    11461 ccgccaagaa gaccgccggc gtgctcggcg acgacctcgc cctcaacgcc cagcaggtca
    11521 ccggcgtgca ggccagccgc gagctgccgg tggtgtgggc ggtggccaag ggctcgctgg
    11581 tcaacaaggc catcctggtg ccggccgcct tgctgatcag ctggctggcg ccgtggctga
    11641 tcaccccgct gctgatgctg ggcggcgcct tcctgtgctt cgagggcttc gagaagctcg
    11701 cgcacaagtt cctgcactcg aaggcggagg acgaggtcga gcaccgcgag accctgcagg
    11761 cggtcgccga cccgaacgtg gacctggtcg ccttcgagaa ggagaagatc aagggcgcgg
    11821 tgcgcacgga tttcatcctc tcggccgaga tcgtggtgat caccctcggc accgtggccg
    11881 cggcctcgct cggccagcgc gtggcggtgc tggtcggcat ctcgctgctg atgacggtgg
    11941 gcgtgtatgg gctggtggcg ggcatcgtca agctcgacga cctcggcctg cacctgcagc
    12001 gcagcacctc ggccttcacc cgccgcatcg gcggcgccat cctgggcttc gcgccctggc
    12061 tgatgaagac gctgtcggta gtcggcaccg cggcgatgtt catggtcggc ggcggcatcc
    12121 tgctgcacgg ctggccgacg gcggcgcacg cggtggagca ttttgcggaa ggcttcggcg
    12181 gtgtgggcgg cgcgctgatc aacaccggcg cgggcgcggg ggtcggcatc ctcgccggcg
    12241 ccgtcgtgct ggcgggagtg atgctggtgc agaagctgcg cggcgcccac tgaacgcacc
    12301 cggcgccatc gccccacgcg cgcatcgacc gccgctcgcg cgtgcgccac gcctgtgacg
    12361 gccgcccgca gcggaagtcc gttcagcagc ggcgcggccc gcggatcgcc acctcgcact
    12421 ggctcagcat gatcgcgtcg gccattgccc atagcacgtc gagcttgaac tgcaggatgt
    12481 cgagcgcgcg ctgctgcatc gccctgctcc ggctgaagta ctcgagcgtg aagcgcaggc
    12541 cgtgctcgac gtcgcgccgc gcctgggtga ggcggttgcg gaagtactgc aggccggcgg
    12601 cgtcgaccca ggggtagtgc gtcggccagg tgtccaggcg ctgctggtgg atgtgcggcg
    12661 cgaagagttc ggtgaggctg gaggccaccg cctcctgcca agggcgccgg cgggcgaagt
    12721 cgatgtaggc gtcgaccgcg aagcgcgtgg cgggcgcgac gaagcgcagc gaggtgacgt
    12781 cgtcgcggga gagacccgtc gcctcgccca gccggatcca ggcctcgatg ccgccggggt
    12841 ccttgacgtc gccgatctcg aagccgtcgt ggtcgaggat gcgctggatc cactcgcggc
    12901 ggatcgcgcg ctccgggcag ttggacagaa tggcggcgtc cttcaccggg atcgagatct
    12961 ggtagtagaa gcggttcgcc acccagccct ggagctgttc gcgggtgagc ttgccctcgg
    13021 ccatcatcac gtggaagggg tggtggatgt ggtagctcgt gcccttctcg cgcagcaggg
    13081 cctcgaactc ggccgggctc cacggcggca ggtcgtcggc acgggcggcg agcgccgcgg
    13141 tgtgctcgat gctggtctgg tcgatgtagc tcacagcgcg atctccatgc cgtcgaaggc
    13201 gacctcgatg ccgtgcgcgg ccagttcggc gcgctcgcgg ctgtcctcgt cgaggatcgg
    13261 gttggtgttg ttgatgtgga tcagcacctt gcgcgtggtg gccggcagct tgtccagcca
    13321 ctcgagcatg ccgccggggc cggattgcgg caggtggccc atggcgcgcg aggtcttcgg
    13381 cgaggcgccg aggcggatca tctcgtcgtc ggtccacaag gtgccgtcga ccagcacgca
    13441 gtcggcggcc tgcatcgccg cccacagttg gggttccatc tcgccgaggc cgggggcgta
    13501 gaacaggcgc ttgccgctgg ccgcatcgac cagggtgacg ccgatgttat cgcccggctg
    13561 cgggcggtcg cggtgcggcg agtagggcgg cgcattgctg gtcagcacca gggcctcgag
    13621 gccgaggccg ggcgcgccgt cgatggcaaa gcgcacctgc agcggcagct cgcgccagtc
    13681 gactccgctg tagtggccga gcacgccgaa caccgggttg cccaccgaca ggtcctcgcg
    13741 cacgcaggcg gtgcaccaca ccggccaagg ctcgcgatgc tcgcgcagca tgtagaggcc
    13801 ggtggtgtgg tcgatctggg catcgatcag cacgatcgcc gcgatgccgg tgtcgcgcag
    13861 cgcgcgcgcc ggctgcagcg ccgggaagct ccggatctgc tgcagcacgt cgggggaggc
    13921 gttgaacagc acccagttct cgtcgtcgcc actggcggca atcgaagact gggtacgggc
    13981 ctgggcgcgg atgcgtccct tgcgcaggcc gtcgcagttg gggcagttgc agttccactg
    14041 cggaaagcca ccaccggctg cggagccgag cacgcggatc ttcatcgctt ctcctgtctt
    14101 gtgtccctgc gggatggggg acgctcgcaa gcaccgccga ccgcttcgac gacgatgcct
    14161 gcaagattga ccgggagaag aacgctccgc atcgtgaaag cccggaaccg ggcctcgtga
    14221 aaataccgag tacggtggcg gcatgactcg agaggtactg catgggcgga ggtcggcgcg
    14281 atgcgcggca ctgcgtgtcc gcagctcggc tgcctgcgat catcggcccc aagcgagtcc
    14341 cgccagcgcg aacaattcgg cgacggcggc gctgcctccc caccacagca gcagcaccga
    14401 ggcggccgcc accagcgtca ccaggtagcc gaccagcagc atcagtccat cgcgcaggcg
    14461 caagccccag gagatcagca cgatggccag cgcgggcagc acgttgtcga agctgatgat
    14521 gggcacgggc gtcatcatcg acagcccggc gatggagagc atggaggcgt tgagcacgcg
    14581 cgccgggcgg tcgctcaggc gcagcaggcg ggggcggccg agggacgcga cgatgccgac
    14641 gacgcggccg aacatgcgct gcagcagcgc cctcgcgcga ccgtcgatct cgcgccgggc
    14701 gagccagcgc ggcaagggca cgggctggcc gacgcacagc ccgaaggcga tcagcaggca
    14761 gaagccgccg acgaccgagg ccatgcccgg gagcgcgacc ggaaaaagca gcggcatcgc
    14821 cagcagggac agccacacca gccgctgccg gttgctctgg ccgagggcct cggccatcgt
    14881 gccgtccatg gacgcgagat gcgccccggc aatgcgttcc acgcttgccc gccgtttggc
    14941 cttgaggaac tcggatcggc tgggtgcgcg ggggtcctgg tcttccatga cggtccaagg
    15001 gtgatcgatc ggtacgagac acgagggtgt ctgcgctgct gcgggaacat cgaattttcg
    15061 ctcgaaagtt cggacaggtt ccgaccttcg acggttcccc cgggtcgagc cccgctgcgg
    15121 aaggcgccgc cgcgaccggc gcgcgccgtt tgcgcgccgg ggtcgggaga gcgttttggt
    15181 ggtacggttg ggccctcctc gtccgcaggc cccatgccgc gggccctcct acgacgttcg
    15241 ccaaccgggt gcagcatgag cgatgccttc cagcccgcgt cgatcggcgc cgacggcaca
    15301 cgccgcgccg cgatgccggt cccgcgcctc gacccggaat ccgccctgct gttcgtgatc
    15361 aacgccgccg cgggcgcgct cgacgtcgat gccaagcgtg ccgtgatcga atcgaccctc
    15421 gccgcccggg gccgcagggg cgagctgctg gtctgcgcgc cggacgagct tgcgcgcgtg
    15481 gccaccgaag ccgcagcggc ggcgctggcg cgcaacacgg cggtggtcgc cgtcggcggc
    15541 gacggcagcc tcggcacggt ggcacaggcc gcgcacgcgg cgggttgccc gatgggagtc
    15601 atcccctacg ggaccttcaa ctacttcgcg cgcacgcacg gcatccccac cgagcccgcg
    15661 gccgcgatgc gccaagtgct ggatgcgcat ccgcgacccg tgcaggtagg ggccatcaac
    15721 gaccgcgtct tcctggtcaa tgccagcctg ggcgtctatc ccgagctgct gcaggaccgc
    15781 gaggcctaca aggcccgctt cggccgcagc cgctgggtgg ccttcgtcgc cggctgcgcg
    15841 acgctcttgc gtgcgcagcg ccggctgcgc ctgcacatcg agatgggctc cacggttcgc
    15901 gacgtgcaga cgctgaccct cttcgtcggc aacaaccggc tgcagctgca gcagctcggc
    15961 gcggagcccg cggacaccgt cgccggcacc cccggcgacg gctgcctggc cgcgctgatg
    16021 ctgcggccca tcggcacgct gtcgatgctc gggctgatgc tgcgcggagc gatgggtcgg
    16081 ctgggcgaag ccgccggcgt ggaaggcttc gagttcaccc acatggcggt gaagcccagg
    16141 ctggcgcgcg gtcgcaggga ggtcatggtg gccttcgacg gcgaggtggc gcgaatgcgc
    16201 gcgcccatcc acattggcgt gctcgacaag cccctgtacc tgctccaggt gcttggcagg
    16261 gcgaactcgc ctgcggccgg cgcatgaggg cggcggcatg agcgtcctcc tgcacatcgc
    16321 ggacacgcat ttcggcaccg agcggcgatc ggtggtcgag gccctggtcg cgctggcggc
    16381 gcagcagcgg ccggatctgg tggtgctcgc gggcgacgtc acgcagcgcg cgcgccccgg
    16441 ccagtttcgc gccgcgaagg ccttcgtcga ccggctgggc gcgccggtcc tggcggtgcc
    16501 gggcaaccac gacatcgccc tgttcgaccc gtgggcgcgc ctgacgcgcc cgtacgcgcg
    16561 ctgggccggg gccttcggcg ccgatctcga gccggtgcac gcgtcggcag agctgctcgt
    16621 cgtcggggtc aacaccacgc gcgcctggcg gcacaagaac ggcgaggtgt cggcggcgca
    16681 gatcgatcgc gtggcaggcc tgctggccac cgcgagtccg cagcagctgc gcgtcgtggt
    16741 ggtgcaccag cccgcagcgg tgatccgcag ccgagaccgc gccaacctgc tgcgcggcca
    16801 ccaggccgcg ctgcaggcct ggtcggtcgc cggcgccgac ctcgtcctcg gcgggcacat
    16861 tcacctgccc tacacgctgg caccgccggg gctggcgcgc cggctctggg tgctccaggc
    16921 cggcaccgcc gtctcctcgc gcacgcgcgc cgaggtgccc aactcggtca atatcgtgcg
    16981 ctggaacgag ccatccggag cccacgacgc accggcgcaa caggggtcgg cagcgggtgg
    17041 aagctgcctg atcgagcagt gggatttcgt gcgccgcgat ggctgcttcg tgcgcaaggc
    17101 ggtcacgccg gtacagccgg agcgctcctg atcgcgcgtc ccctgcgggt acatggcaag
    17161 cccctcgtgc cctcgggcag ccggtgcggc gcgggcgcgc cgagccggcg ccgccaccct
    17221 cgcgcgccgt gcatgcggct gcgggcgcga gactcatgat tttctgtagg cggcgctgga
    17281 gcttgtgtcg aggccggggc gagcggcgat ccgcgacaat cccctggaaa gtcacgcccg
    17341 cagaggagtc cgaccgtgaa agccgagcag cgcgcaatcc ccaccgcccc caccctcccc
    17401 gtcgccagcc acgagccccc gcgcgcgaag aagctcgcag ccctgctccg cctcggcgtt
    17461 ccgggcgcac ttgcgggctt cgcctgcctc gccggcgcac agccggcgga cccgggagcg
    17521 gtggcgctca acccggtcgt ggtcaccggc gcacccgccg ccaccgagag cttcgagctg
    17581 ccctactcgg tcgattcggt ggacatgcgc gccaaccagg ccggcaacct cggcgtgaac
    17641 gcctccgagg cgctcgccgg cgtgcccggc ctggtgatcc agaaccgcca gaactatgcc
    17701 caggacctgc agatctcggt gcgcggcttc ggcgcgcgcg cggccttcgg cgtgcgcggc
    17761 gtcaagctca tcgccgacgg catcccggcc accaacccgg acggccaggg ccaggccgcg
    17821 accttcaacc tcgacaccgc cgaacgcatc gaggtgatgc gcggcccctt cgccaccgtc
    17881 tacggcaacc acgccggcgg cgtcatccag cttttctcgc gcaagggcga gggcgatccg
    17941 cgcgtgcgcg cgagcgtgct cggcggcagc tggggcacga ccaagttcgg catcggcgcc
    18001 gagggcgaga agaatggcgt cggcttcgtg ctcgacgcct cgcgcttcga caccgacggc
    18061 taccgcgacc acagcaagac ccgccgcgac cagggcttcg ccaagctgac gctgaacccg
    18121 gacgaggaca gcacgctgac cctggtggcg aacgggctgc gccagccgga gacggaggat
    18181 ccgctggggg tgacctggga gacctacgag cgcgatccgc agtcgctcac gatcgatccg
    18241 ctcgaccccg cgacgccgaa gcgctcctat gcagcccgct acaacacacg caagagcatc
    18301 caccatgttc agggcggagc gacctacgag cgccggctag gcgaggaccg cctgcagttg
    18361 tccgcctatg ccgggcgccg cgcggtgacc cagtaccagt ctttttccaa aggcttccag
    18421 tccagcccgc gccatgccgg tggcgtggtc gatttcgacc gcgactttca cggcatgggg
    18481 ctacgctgga tttcgcagcg cacgatggga agcggcgagc tcaccctgac cgccggcatc
    18541 gactacgacc actccgagga cgatcgtcgc ggctacgaga acttcgtcgg cagcacgctc
    18601 ggcgtgaagg ggcgcctgcg ccgcgacgag ctcgacacca tcaccagcat cgacccctat
    18661 gtccaggcgc tgtggaagag cggaccgtgg cagtggtcgc tcggcgcccg ccattcgcgc
    18721 gtgtcgttca aggtggagga tcgctacatc aacaccgaca acccggacga cagcggcagc
    18781 gtacgcttca gcaagaccac gccggcgctg ggggttagct acgcattgag tccggcgacg
    18841 aacctctatg cgagcgtggg cgcgggctac gagacaccca ccctcaacga gctctcgtac
    18901 gcgacaccca ccaccggctt caacttcggc ctgcgtccga gcaccagccg ccaggcggag
    18961 atcggcatca agaccttcgt cggcgacgac gcccggatca acgccgcgct gttcaggatc
    19021 gagaccgacg acgagatcgt cgtgttggcc tcggaagaag gccgtaccag ctaccagaac
    19081 gccggccgga cattgcgcca ggggatcgag atcgccgccc aggcggagct cacccgcacg
    19141 cttacggcgc gggcctcgct gacctggatg caggccgaat acgacgaggc cttcaagagc
    19201 cgcgggacca ccgtggcggc cggcaaccgt atcccaggcg ttccgcgcat cgcggcgttc
    19261 gccgaactcg cctggcaggc ggcccccggg gtgacgctcg ccggagaggt cttgcatcgg
    19321 ggcgaggtcg aggtgaatga cctcaacaac gaccgcagcg cgccggccta cacgcttttc
    19381 aacttgcggc tgtccgcgga gcagcaacaa gggccctgga ccttcgggca actgctgcgc
    19441 gtggataacg tgctcgatcg caaatacgtc ggctccgtga tcgtcggtga tagcaacaag
    19501 cgctattacg aaccgggccc cgagcgcagc gtgtatgccg gggtgagcgc gagctaccgg
    19561 ttctgagcgc ggccgccggc gctcctacct gaaccggcgc ggatcgcggg ctcttgtagg
    19621 agcgccggca ggcgcgaaca aggccgcggg gaaagg
//
LOCUS       DAOTIN010000055        19602 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_3339_length_19602_cov_8.914974, whole genome shotgun sequence.
ACCESSION   DAOTIN010000055 DAOTIN010000000
VERSION     DAOTIN010000055.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 19602)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 19602)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19602
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3339_length_19602_cov_8.914974"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..509)
                     /locus_tag="P5537_09745"
     CDS             complement(<1..509)
                     /locus_tag="P5537_09745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HRV78364.1"
                     /translation="MTTRRIIPLTPAATPARALALPERPRLEAPPPLSVYVHFPWCVK
                     KCPYCDFNSHAPREGGIPQQAWLDAVLADLQHALPQVWGRRVNSVFIGGGTPSLMSAA
                     TLDGLLTGLRMLLPLDPLAEVTLEANPGTVEAERFRDYRAAGVNRLSLGIQSFDDAML
                     AKIGRIHGG"
     gene            complement(568..1173)
                     /gene="rdgB"
                     /locus_tag="P5537_09750"
     CDS             complement(568..1173)
                     /gene="rdgB"
                     /locus_tag="P5537_09750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RdgB/HAM1 family non-canonical purine NTP
                     pyrophosphatase"
                     /protein_id="HRV78365.1"
                     /translation="MSKRLVLASNNAKKAAEMQALLAPLGIEVIPQSVFGVGEAEEPH
                     PSFVENALAKARHAAAATGLPAVADDSGLCVEALGGAPGVISARFAGEPRSDARNNAL
                     LLEKLAHLTEPAQRRAYFYSAVVLVRHAEDPRPLIADGEWHGEILPAARGEGGFGYDP
                     LFWLPELEQTAAELEPALKNTLSHRGAAMRHLLDRLAEHPL"
     gene            complement(1201..1932)
                     /gene="rph"
                     /locus_tag="P5537_09755"
     CDS             complement(1201..1932)
                     /gene="rph"
                     /locus_tag="P5537_09755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004549 - tRNA-specific ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HRV78366.1"
                     /translation="MRPSQRQPDQLRPVRLTRGFTCHAEGSVLVEFGATRVLCTASVE
                     EAVPGFLRGKGQGWVTAEYGMLPRATHTRSAREAAKGKQSGRTQEIQRLIGRSLRAVV
                     DLAALGERQIVVDCDVLQADGGTRTAAITGACVAVHDALVGLVAAGKLARNPMREFVA
                     AVSVGIHQGLPVLDLDYAEDSDCDTDMNVVMTEGGGLIEVQGTAEGTPFSRAELNALL
                     DLAELGGRQLFELQRTAVRTAILTA"
     gene            complement(1942..2865)
                     /locus_tag="P5537_09760"
     CDS             complement(1942..2865)
                     /locus_tag="P5537_09760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein phosphatase"
                     /protein_id="HRV78367.1"
                     /translation="MRFTIYQESRPGKRRDNQDRIAHCYSRDALLMLVADGMGGHLHG
                     EVAAQIAVQRIAERFQAEARPLLPDPQLFLARAIERAHQAILDHALDHHFPEAPRTTL
                     VACVIQRGAAYWAHAGDSRLYLLRRGHLVTRTRDHSRTQLMIDQGVIKAEEAHLHPGR
                     NRIYSCLGGNFNPQVEYSPRTPLRDGDLLALCTDGVWGPIDDDGLVVNLTAGVLSQAV
                     PRLLDISERKAGPTADNLSMVAMCWHDEHAVGAATVESISTRTMELDGFESRLDLSGT
                     APGATAEFDEDEIERAIREINAAIHKIDSRT"
     gene            complement(2875..3822)
                     /locus_tag="P5537_09765"
     CDS             complement(2875..3822)
                     /locus_tag="P5537_09765"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein kinase"
                     /protein_id="HRV78368.1"
                     /translation="MPSQANCALPPGFQLDQYRIERQLSLGGFSIVYLARDAHGQAVA
                     IKEYLPNSLALRKEGETEPQVSEEHRLAFRYGMKCFFEEGRSLAKLMHPNVVRVLNFF
                     RANGTVYMVMQFERGRTLHDYIRKHRGEVKELLIRAVFARMLNGLREVHAHKLMHLDI
                     KPSNIYLRNDGTPVLLDFGAARQTLMSDQPVLKPMYTPGYAAPEQYEKGAQIGPWTDI
                     YSVGASLHACIVGSPPPRADERTQQDTLQPVVKTQAGRYSRQLLELTDWCLHLDPQQR
                     PPSVYALQKALIHQDNAPERPEHWFSDLGSRLRSFIGRS"
     gene            3914..4780
                     /locus_tag="P5537_09770"
     CDS             3914..4780
                     /locus_tag="P5537_09770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HRV78369.1"
                     /translation="MVQSMTGFAVQTRDLGSISLHLELRSVNSRYLDLGFRIVDDLRA
                     AEPAIRERISARLGRGKVECRLNLQAGHAAPRSMALNGALLDQLAAAQDGLRARFPDA
                     PPLSVSELLRWPGMLADDSLGFDEMLPAIVALVDTALEELVATRQREGDKLADMIRER
                     VARMRELVAQAAPRMPAVVLEYQERLTAKLRDAVASLDEDRIRQEVALYAQRIDVDEE
                     LTRLSTHLDEVERILKSAGAAGKRLDFLMQELNREANTLASKSPATDITAIAMEMKVL
                     IEQMREQVQNLE"
     gene            4830..5444
                     /gene="gmk"
                     /locus_tag="P5537_09775"
     CDS             4830..5444
                     /gene="gmk"
                     /locus_tag="P5537_09775"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HRV78370.1"
                     /translation="MAGTLFIVTAPSGAGKTTLVRGLLQRDPRVQLSISYTTRAPRPG
                     EQDGREYNFVDVPTFRALRDRGEFLEWAEVHGNYYATSRVWLKQQVDAGRDTLLEIDW
                     QGAQQVRKHFPDAVGVFILPPSMEELEARLRGRNTDSDEVISRRLLGARGEMRHVAEF
                     DYVIINDEIDAALDDLVAVVRAARLRCAKQHQRHPEYFAFLEQD"
     gene            5447..5662
                     /gene="rpoZ"
                     /locus_tag="P5537_09780"
     CDS             5447..5662
                     /gene="rpoZ"
                     /locus_tag="P5537_09780"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004337176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000345 - cytosolic DNA-directed RNA
                     polymerase complex [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HRV78371.1"
                     /translation="MARITVEDCLKKIPNRFQLTLAATYRARQLTAGGTPQIDVDPLD
                     RDKPTVIALREIEAGKVGLEMLNRGQA"
     gene            5680..7887
                     /locus_tag="P5537_09785"
     CDS             5680..7887
                     /locus_tag="P5537_09785"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HRV78372.1"
                     /translation="MKAAEAGPAPQVFRPPVSSVLALDFQQLKAKLQTYLKPEDVGRV
                     EAAYHFSADAHAGQFRVSGEPYVSHPVAVCSLVADWHLDPQALIAALLHDVMEDTHIT
                     KAEIAERFGKVSAELVDGLSKLDKIEFRSQEEAQAENFRKMLLAMASDLRVILIKLAD
                     RLHNMRTLDHMRPAKRRRIANETLEIYAPIANRLGLNDLFRELQELSFRNKYPLRFEV
                     LAKAIRSARGNRREVVGKILASIEERLPQWGIGAEVQGREKHLYGIYRKMAEKRLSFS
                     QVLDIYGFRVIVKDVPSCYLALGALHSMYKPVPGKFKDYLAIPKANGYQSLHTTLIGP
                     FGMPVEVQIRTREMHHIAETGVASHWLYKEDEKTLTELQQKTHSWLQSLLELQSASGE
                     ATEFLEHVKIDLFPGEVYVFSPKGKIFSMPKGSTPVDFAYAVHTDVGNRCVACRINGD
                     LMPLRSELRNGDQVEIITAAQANPNPAWLSYARTGKARAQIRHFMKNAQQDESVTLGE
                     RLLNQALRPHGLTLGQISSFAWDRFLRDRGVRHKKEVFSDLGLGKRLPVIVARRLAEA
                     QDLESGRPDVVKPKPAGAISIRGSEGVAVQLARCCHPIPGDPIIGTLRKGQGLEVHTH
                     DCPNVAKLRGDRGRWVDVEWEHMVDDRLFDVGIRVLSHNARGVLARVASAIAEEDSNI
                     QSVSMDGGQGEYTALNFTVQVRDRMHLARVMRGVRRVQEVVRIGRVKADGRVG"
     gene            7975..8163
                     /locus_tag="P5537_09790"
     CDS             7975..8163
                     /locus_tag="P5537_09790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3460 family protein"
                     /protein_id="HRV78373.1"
                     /translation="MAMYESDHTKFMREWMEKHPEQRDEQKKGRALWWDKPQSVEEQK
                     RVATARVPVKPYYYDINN"
     gene            8276..9727
                     /locus_tag="P5537_09795"
     CDS             8276..9727
                     /locus_tag="P5537_09795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HRV78374.1"
                     /translation="MSLPSRLAFIDVESTGAHPVRDRITEIAILRVEDGEVVARWESL
                     VAPGQPIPPLIEEVTGISDAMVADAPAFEAVADTVAALLEGCVFVAHSARFDYGFIRN
                     AFTRIGREFEAPVLCTVKLSRALYPEHHRHGLDALIERHGLVCSARHRAMGDVEALWQ
                     FVRVLEAGFEPEVLARAATRAMKAPAQPPGLPEGLLEALPDAPGLYLFHAQPEPPPLG
                     ARDPALFVGRAQSLRARVREHFGAGARKGRDAELAARVKRVEWVETAGELDTSLRENA
                     LLRALAPPYNRPQEPAGAAFALRLLPNRRRAPIYETVAIAGTDPADWHGLHGVFRNRR
                     EADNLLRELALLYRLCPRRLGLEGGNGPCTAYASRRCAGVCARRETPEEHDARLAGAL
                     AGVGVRPWPWAGPVVVEEARAHGPRRLQVFDRWCHLGSAQDEAGALALATAPRAFDAD
                     VWRILARWLAVPAHLAQVRELAAQADEEAPGAA"
     gene            complement(9724..10425)
                     /locus_tag="P5537_09800"
     CDS             complement(9724..10425)
                     /locus_tag="P5537_09800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HRV78375.1"
                     /translation="MSCRPPSLAPDASDLLARFAPFDMLDACARERVLAAARPIHAAR
                     GELLVQQEDCPRGIYLVLDGRVKCFVLSPSGGEKIVRLAEPGSFFGEEAALINRPHVA
                     NAQAISATELLLVPTAALRNAMVSSTAFSVSMSNRLAEASYDLMSTMQVQFQLSGTQR
                     VAHYLTRLAPDDAERWEIRLDIDKQTIAAQLNLTPETLSRILSQLTRDGMIQPRGRRG
                     MVLSKLSQLRDCAAH"
     gene            10672..12585
                     /locus_tag="P5537_09805"
     CDS             10672..12585
                     /locus_tag="P5537_09805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HRV78376.1"
                     /translation="MHLAVPRRLVRRSIMLLVSVALVAMTLIGLAGMSASFLVVDRSR
                     DSVRAIDVAGSLRSHTRRIANLIAIDALKGRVGVSERTRAAMADIERELQEPALRRFG
                     DAAPGELFAATYRGVQAGWERTVRPRIEALDGHGPPDAREIEALLAGVDDFVGQVDSL
                     VAVLGQENERRIDELRRILALAAAVTLGVVLVVIVLLQRALLRPLGGLLDAARRIAGG
                     DFGVRVRYTGEDELGQVGSAFNLMADELARHYHLLEQRVTEKTAELQRSNRSLELLYH
                     AIARLYQAPSAPDAYDATLRDIDRVAGLEGSFVCIEPRPGAPAAVIASSMGPCPDRAE
                     RGEDACAACRAGSEGQALALLSPTLLRFPLRDREHHYGMLRLSLPDGARLEDWQRQLV
                     EALSRHMGMALGAARRTEQERLLALQEERSVIARELHDSLAQALSYMKIQVSLLQRAL
                     ADPARAAEAEPILADLREGISAAYRQLRELLVSFRLGLSADLATLMEDAAREYGTRGG
                     LEVALAVELGACQLGPNQEVHVLQIVREALSNMVRHAAARHAWVELRGGADGEVRLEV
                     RDDGCGIGAPPADARNHHGLAIMRERARSMGGEIEIGPALPSGTRVCVRFRAANAGVA
                     AMVQGDAKKEMEP"
     gene            12582..>13219
                     /gene="narL"
                     /locus_tag="P5537_09810"
     CDS             12582..>13219
                     /gene="narL"
                     /locus_tag="P5537_09810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator NarL"
                     /protein_id="HRV78377.1"
                     /translation="MNESCRVLIVDDHPLFRRGLVQLLRTIPAFVLVGEAASGAEGLV
                     LARELRPDLILLDLNMRDGDGLDMLRGLRTARSEARVVMVTVSDSGEDVVAALRGGVE
                     GYLLKDMEPEAMLEALQDVAAGRVVIPPQLNHLLAAALRGESRPQSAGAAGLTEQELR
                     ILEKIAAGLSNKQIGRELDIAEGTVKVHVKHILRKLELRSRVEAAVWAVEHLR"
     assembly_gap    13220..13319
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <13320..13814
                     /gene="napF"
                     /locus_tag="P5537_09815"
     CDS             <13320..13814
                     /gene="napF"
                     /locus_tag="P5537_09815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-type protein NapF"
                     /protein_id="HRV78378.1"
                     /translation="RNFFFGRTRAVEPALRPPWALEEDDFVARCTRCDRCIEACPTSI
                     LVRMDGGFPGVDFGRGECTFCGDCVAACEPRALQRDATTAPWDRVAVIGEACLAARGV
                     ECRVCGESCPEGAIRFRPRLGGVAHPQLDAAACTACGACIGPCPTRAIDTRARESLPT
                     ESET"
     gene            13811..14065
                     /locus_tag="P5537_09820"
     CDS             13811..14065
                     /locus_tag="P5537_09820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone NapD"
                     /protein_id="HRV78379.1"
                     /translation="MNIASLVVRAFPADFPEVVEGLKKVPGVELHGQSAEKGNIVITI
                     EDGAGWSVTDSILAVNLLPKVQGLTIAYEYTDEGLELTEV"
     gene            14067..16613
                     /gene="napA"
                     /locus_tag="P5537_09825"
     CDS             14067..16613
                     /gene="napA"
                     /locus_tag="P5537_09825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008940 - nitrate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0030151 - molybdenum ion binding [Evidence
                     IEA];
                     GO_function: GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase catalytic subunit NapA"
                     /protein_id="HRV78380.1"
                     /translation="MSMNRREFIKNNAIAAAAATAGIGIPVVAEAQQPGAGSTKVRWD
                     KAACRFCGTGCSVLVGVQDGRVVATQGDPDSPVNRGLNCIKGYFLSKIMYGEDRLTKP
                     LLRMKNGQYDKNGEFTPISWDQAFDIMEQKWKKAIKEHGPDSVAMFGSGQWTVWEGYA
                     ASKLMKAGFRTNNLDPNARHCMASAVAGFMRTFGIDEPMGCYDDIENTDTVVLWGSNM
                     AEMHPILWSRITDRRLSKEGCQVHVLSTFEHRSYELADNPMIFVPQTDLAILNYICNH
                     IIQAGKVNKAFVERNVKFKIGEGDIGFGLRPNHPLEAKATSNGYPGADGKPKGDTGAA
                     KDCSFDDFAKFVSEYTLEKVSKLSGVPQDRLLKLAEQYADPNRKVTSFWTMGFNQHTR
                     GTWVNNMIYNVHLLVGKISEPGNSPFSLTGQPSACGTAREVGTFAHRLPADMVVMNPM
                     HRALSEEIWKLPEGTISPKIGYHAVAQSRALKDGKLKCYWTSTTNNMQAGPNVNDEIY
                     PGWRNPEAFVVVSDVYPTVSALSADLILPCAMWAEKEGAFGNAERRTQFWRQQVSAPG
                     EAKSDLWQYIQFAKRFKVEDVWPEELIAKKPEYRGKTLYDVLYANGQVNKFPLEDVEK
                     ANGHAWAGYMNDESKELGFYLQKGLFEEYAAFGRGHAHDLADFDVYHKARGLRWPVVD
                     NKETLWRFREGYDPYVKAGEGVKFYGYKDNKAIIFALPYQDPPEMPDAEFDMWLCTGR
                     VLEHWHTGSMTRRVPELHRSVPDAQIFMHPEDAQKRGLQRGMAVKVVSRRGEIVARLE
                     TRGRNKPPVGLIFVPFFDEGRLVNKLTLDATCPISKETDYKKCAVKVLKA"
     gene            16677..17576
                     /gene="napG"
                     /locus_tag="P5537_09830"
     CDS             16677..17576
                     /gene="napG"
                     /locus_tag="P5537_09830"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-type protein NapG"
                     /protein_id="HRV78381.1"
                     /translation="MAMNDKVQSSGRAEPVAPASRRRFLKDAAGVAGGAGLLALGAGM
                     YAKQASALPATAIRPPGALPEDDFLAACVRCGLCVRDCPYKTLKLAELGDGVATGTPY
                     FEARDIPCEMCEDIPCVVACPTGALDRALVDIAKAKMGLAVLIDQENCLNFLGLRCDV
                     CYRVCPVIDQAITLERIHNPRSDRHAMLLPTVHSEYCTGCGKCEKACVLPGESAIKVL
                     PIKLAQGSKAEHYLRGWEEKEAAGKSLIGDQVELPVRGLEGKAYGDTRVEPGQGPVQG
                     GTQVPDYAPAKPAGGGLDSGWKP"
     gene            17573..18508
                     /gene="napH"
                     /locus_tag="P5537_09835"
     CDS             17573..18508
                     /gene="napH"
                     /locus_tag="P5537_09835"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinol dehydrogenase ferredoxin subunit NapH"
                     /protein_id="HRV78382.1"
                     /translation="MSAHASSGAAPERKVPPTSVRGAAMRGVVARPGREAVEAKGWLR
                     AHKWLLLRRASQLGILALFLVGPWLGWWIVKGNLSSSLTLGVLPLTDPFLVAQQLAAG
                     QWPYQEALLGAGIVLAFYLLFGGRLFCSWVCPVNLVTDAAAWLRRRLGLKGGKAPSGS
                     TRYWLLGFVLVIAAATGSLAWEWVNPVSMFHRGLIFGFGLAWGIVGGIFFYDLLIAPR
                     GWCGHLCPQGAFYALIGRAAVVKVSADKRSACNDCMDCFAVCPEPQVIRPALKGVGQD
                     HPLILDADCTTCGRCVDVCGKDVFRITTRFNRSES"
     gene            18505..18957
                     /locus_tag="P5537_09840"
     CDS             18505..18957
                     /locus_tag="P5537_09840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase cytochrome c-type subunit"
                     /protein_id="HRV78383.1"
                     /translation="MKKQTRNLVLALVAAVGFGAVVPPAAMAQAVKSIRGADVAEQEL
                     QVGNYKPIPDQAPIDRDYVQQPPLIPHKVEGYEVTLNFNKCMDCHAWSRYKESGATKV
                     SLTHFKDRDGGELSNISPRRYFCMQCHVPQTDAKPLVANKFQRAEGLR"
     gene            18981..19601
                     /locus_tag="P5537_09845"
     CDS             18981..19601
                     /locus_tag="P5537_09845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NapC/NirT family cytochrome c"
                     /protein_id="HRV78384.1"
                     /translation="MTDNNKSLMQRIRGAGWGAIVLLVAAGVVFWGGFNWALEMTNTE
                     KFCISCHEMEDNVFKEYRNTIHYQNRTGVRATCPDCHVPKEWGPKMIRKIKASRELYG
                     KVMGTIDTPEKFAAERLRLAQNEWTRMKANNSQECRNCHNYEYFDYSVQGRRSNQMHQ
                     AGFAEGKTCIDCHKGIAHSLPPVDQHIGAPREGVAPEVMHPPVKKD"
BASE COUNT         3001 a         6675 c         6918 g         2908 t
ORIGIN      
        1 tcgccgccgt ggatgcggcc gatcttcgcc agcatggcgt cgtcgaagct ctggatgccg
       61 agcgacaggc gattgacgcc ggcggcgcgg tagtcgcgaa agcgctcggc ctcgaccgtg
      121 ccggggttgg cctcgagcgt gacctcggcg agcgggtcga gcggcagcag catgcggagg
      181 ccggtgagca ggccgtcgag cgtggccgcc gacatcaggc tgggggtgcc gccgccgatg
      241 aacacactat tcacccgccg gccccagacc tggggcaggg cgtgctgcag gtcggcgagc
      301 acggcgtcca gccaggcctg ctgggggatg ccgccctcgc gcggggcgtg ggagttgaag
      361 tcgcagtagg ggcacttctt cacgcaccac gggaagtgca cgtacaccga cagcgggggc
      421 ggggcctcga gccgggggcg ctcgggcagc gccagggcgc gcgccggcgt ggcggcgggg
      481 gtgaggggga tgatgcggcg ggtggtcacg aggggcggtg gtccggtgcg ggctgtccgt
      541 gttggcgcgg tcgcggtggg agcggggtca gagcgggtgc tcggcgaggc ggtcgagcag
      601 gtggcgcatc gccgcgccgc ggtggctgag ggtgttcttc agcgcgggtt cgagctcggc
      661 ggcggtctgc tccagctcgg gaagccagaa cagcgggtcg tagccgaagc cgccctcgcc
      721 gcgcgccgcg ggcaggatct cgccatgcca ttcgccgtcg gcgatcagcg ggcgcgggtc
      781 ttcggcgtgg cgcaccagca ccacggccga atagaagtag gcgcggcgtt gtgcgggctc
      841 ggtgaggtgg gcgagctttt ccagcagcag ggcgttgttg cgcgcgtcgg acctgggctc
      901 gccggcgaag cgggcggaga tgacccccgg cgcgccaccg agcgcctcga cgcataggcc
      961 ggaatcatcc gccaccgcgg gcagcccggt ggcggctgcg gcgtggcggg ccttggcgag
     1021 cgcgttctcg acgaagctcg ggtgcggctc ctcggcttcg ccgacgccga acacggattg
     1081 cgggatgacc tcgatgccga gcggggcgag cagggcctgc atctcggcgg ccttcttggc
     1141 attgttgctg gcgaggacga gtcgtttgct catggtgcgg gggctcctgg cgaacgggct
     1201 tcaggccgtg aggatggccg tgcgcaccgc ggtgcgctgc agttcgaaca gctggcggcc
     1261 gccgagttcg gcgaggtcga gcagggcgtt gagctcggca cgcgagaacg gggtgccctc
     1321 ggccgtgccc tggacctcga tcaggccgcc gccctcggtc atcaccacgt tcatgtcggt
     1381 gtcgcagtcg gagtcttcgg cgtagtcgag gtcgagcacc ggcaggccct ggtggatgcc
     1441 caccgagacc gcggcgacga actcgcgcat cgggttgcgc gccagcttgc cggcggcgac
     1501 caggccgacc agggcgtcat gcaccgcgac gcaggcgccg gtgatggcgg cggtgcgggt
     1561 gccgccgtcg gcctgcagca cgtcgcagtc gacgacgatc tggcgctcgc cgagcgcggc
     1621 gaggtcgacc accgcgcgca ggctgcgccc gatcaggcgc tggatctcct gggtgcgtcc
     1681 gctctgcttg cccttggcag cctcgcgcgc gctgcgcgtg tgggtggcgc gcggcagcat
     1741 gccgtattcg gcggtcaccc agccctggcc cttgccgcgc aggaagccgg gcacggcctc
     1801 ctcgacgctg gcggtgcaca gcacccgggt ggcgccgaat tcgaccagca ccgagccttc
     1861 ggcgtggcag gtgaagccgc gcgtgaggcg gacggggcgg agctggtcgg gctggcgttg
     1921 gctgggtcgc atcgtgaggt cctatgtgcg ggagtcgatc ttgtggatgg cggcgttgat
     1981 ctcgcggatg gcgcgctcga tctcgtcctc gtcgaattcg gcggtggcac ccggagcggt
     2041 gccggagagg tcgagacggg actcgaagcc gtcgagttcc atggtgcggg tggagatcga
     2101 ttcgacggtc gcggcgccga cggcgtgctc gtcgtgccag cacatcgcca ccatcgacag
     2161 gttgtctgcg gtcgggccgg ccttgcgctc ggagatgtcg agcagcctcg gtaccgcctg
     2221 gctgagcacc ccggcggtga gattgaccac caggccgtcg tcgtcgatcg ggccccacac
     2281 gccgtcggtg catagcgcga ggaggtcgcc gtcgcgcagc ggggtgcgcg gagaatactc
     2341 cacctgcggg ttgaagttgc cgccgaggca ggaatagatg cggttgcgcc cggggtggag
     2401 gtgggcctct tcggccttga tcacgccctg gtcgatcatc agctgggtgc gcgaatggtc
     2461 gcgcgtgcgc gtgaccaggt ggccgcggcg cagcaggtag aggcgcgagt cgccggcgtg
     2521 cgcccagtag gccgcgccgc gctggatcac gcaggccacc agcgtcgtgc gcggcgcttc
     2581 cgggaaatgg tggtcgagcg catggtcgag gatggcctgg tgggcgcgct cgatggcgcg
     2641 tgcgaggaag agctgggggt cgggcagcag cggccgcgcc tcggcctgga agcgttccgc
     2701 gatgcgctgt acggcgatct gcgccgccac ctcgccgtgc aggtggccgc ccatgccgtc
     2761 ggcgaccagc atcagcagcg cgtcgcgcga gtagcagtgg gcgatgcggt cctggttgtc
     2821 gcgccgcttg ccggggcggc tttcctgata gatggtgaag cgcatgaggg gtcctcaact
     2881 gcggccgatg aacgagcgca gccggctgcc caggtccgag aaccagtgct ccggacgctc
     2941 gggggcgttg tcttgatgga tcagcgcctt ctgcagcgca tatacgctgg gcgggcgttg
     3001 ctgggggtcg aggtgcaggc accagtcggt gagctcgagc agctgccggc tgtagcgccc
     3061 ggcctgggtc ttcaccacgg gctgcagggt gtcctgctgg gtgcgctcgt cggcgcgcgg
     3121 cggcgggctg ccgacgatgc aggcgtgcag gctggcgccc acgctgtaga tgtcggtcca
     3181 tgggccgatc tgggcaccct tctcgtactg ctcgggggcg gcgtagccgg gggtgtacat
     3241 cggcttgagc accggctggt cgctcatcag cgtctggcgt gcggcgccga agtcgagcag
     3301 caccggggtg ccgtcgttgc gcaggtagat gttggagggc ttgatgtcga ggtgcatgag
     3361 cttgtgtgcg tgcacttcgc gcaggccgtt gagcatgcgc gcgaacaccg cacggatcag
     3421 caactccttg acctcgccgc ggtgcttgcg gatgtagtcg tgcagggtgc ggccgcgctc
     3481 gaactgcatg accatgtaca ccgtgccgtt ggcacggaag aagttgagca cgcgcaccac
     3541 gttcgggtgc atcagcttgg cgagcgagcg gccctcctcg aagaaacact tcatgccgta
     3601 gcggaaggcg aggcggtgct cctcgctgac ttgcggttcg gtctcgccct ccttgcgcag
     3661 ggcgagcgag ttgggcaggt attccttgat cgccacggcc tggccgtgcg cgtcgcgcgc
     3721 gaggtagacg atcgagaacc cgcccagcga cagttgccgc tcgatgcggt actggtcgag
     3781 ctggaaccct ggtggcagcg cgcagttggc ttgagacggc atcttcgagg gcgctagaat
     3841 cccggttttc gcggtttcct tcctgatcca ggcgcccagt ttactcgatc gggcgcggcc
     3901 cccggagcgc ccaatggtcc agagcatgac aggtttcgcg gtacagacgc gagacctggg
     3961 tagtatcagc cttcacctcg agctgcgcag cgtcaattcg cgctatctcg atctcggttt
     4021 ccgcatcgtc gacgacctgc gcgcggccga acccgcgatc cgcgagcgca tctccgcgcg
     4081 cctcggtcgt ggcaaggtcg aatgtcgcct gaacctgcag gccggccatg ccgcgccgcg
     4141 cagcatggcg ctcaacggcg cgctgctcga ccagctcgcc gctgcgcagg acgggctgcg
     4201 tgcgcgcttc cccgacgcgc cgccgctgtc ggtcagcgag ctgctgcgct ggccgggcat
     4261 gctcgccgac gacagcctcg gcttcgacga gatgctgccg gcgatcgtcg cgctcgtgga
     4321 taccgcgctc gaagagctcg tcgccacccg ccagcgcgag ggcgacaagc tcgccgacat
     4381 gatccgcgag cgcgtcgcac gcatgcgcga gctcgtcgcc caggccgcgc cgcgcatgcc
     4441 ggcggtggtg ctcgaatacc aggagcgcct caccgccaag ctgcgcgacg ccgtcgccag
     4501 cctggacgag gaccgcatcc gccaggaggt cgcgctctac gcccagcgca tcgatgtcga
     4561 cgaggagctc acccgcctgt ccacccacct cgacgaggtc gagcgcattc tcaagagcgc
     4621 cggcgccgcc ggcaagcggc tggatttcct gatgcaggag ctcaaccgcg aggccaacac
     4681 cctggcctcc aagtcgcccg ccaccgacat cactgcgatc gcgatggaga tgaaggtgct
     4741 gatcgagcag atgcgcgagc aggtgcagaa cctggaatga gccgcgcggc gccgcgcgcg
     4801 cccgcgaacc ccgaacacga ggacgcccca tggccggaac ccttttcatc gtcaccgcgc
     4861 cctcgggcgc cggcaagacc accctggtgc gcggcctgct gcagcgcgac ccgcgcgtgc
     4921 agctgtcgat ctcctacacc acgcgcgcgc cgcgccccgg cgagcaggac gggcgcgagt
     4981 acaacttcgt cgacgtgccc accttccgcg cactgcgcga ccgtggcgag ttcctcgagt
     5041 gggcggaggt gcacggcaac tactacgcca cctcgcgcgt gtggctcaag cagcaggtcg
     5101 acgccgggcg cgacaccctg ctcgagatcg actggcaggg cgcgcagcag gtgcgcaagc
     5161 acttcccgga cgcggtcggg gtcttcatcc tgccgccctc gatggaagaa ctcgaggccc
     5221 gcctgcgtgg tcgcaatacc gacagcgacg aggtcatcag ccgccgcctg ctgggcgcgc
     5281 gcggggaaat gcgccatgtc gcggaattcg actacgttat aatcaacgac gagatcgatg
     5341 ccgcgctcga cgacctggtc gccgtagtgc gcgccgcgcg tttgcgctgc gccaagcagc
     5401 accagcggca tcccgaatac ttcgcctttc tcgaacagga ttgaacatgg cccgcatcac
     5461 cgtagaagac tgcctgaaga agattccgaa ccgcttccag ctcaccctgg cggcgaccta
     5521 tcgcgcccgc cagctcaccg cgggcggcac gccgcagatc gatgtcgacc cgctcgaccg
     5581 tgacaagccc accgtgatcg cgctgcgcga gatcgaagcg ggcaaggtcg gcctcgagat
     5641 gctcaaccgc ggccaggcct gataccgccc gggggttgca tgaaagccgc tgaagcaggc
     5701 ccagcccccc aagtcttccg cccgccggtg tcgagcgtgc tcgcgctcga cttccagcag
     5761 ctcaaggcca agctgcagac ctacctcaag cccgaggacg tgggccgcgt cgaggcggcc
     5821 taccacttct ccgccgatgc ccacgccggg cagttccgcg tcagcggcga gccctacgtc
     5881 agccacccgg tggcggtgtg ctcgctggtc gccgactggc acctcgaccc gcaggcgctg
     5941 atcgccgcgc tcctccacga cgtgatggag gacacccaca tcaccaaggc ggagatcgcc
     6001 gaacgcttcg gcaaggtctc cgccgagctg gtcgacggcc tctccaagct cgacaagatc
     6061 gagttccgct cgcaggaaga ggcccaggcc gagaatttcc gcaagatgct gctggcgatg
     6121 gcgagcgacc tgcgcgtcat cctcatcaag ctcgccgacc gcctgcacaa catgcgcacg
     6181 ctggaccaca tgcgtccggc caagcgccgc cgcatcgcca acgagacgct cgagatctac
     6241 gcgccgatcg ccaaccgcct cggcctcaac gacctcttcc gcgagctgca ggagctgtcc
     6301 ttccgcaaca agtacccgct gcgcttcgag gtgctcgcca aggcgatccg cagcgcgcgc
     6361 ggcaatcgcc gcgaggtcgt cggcaagatc ctcgccagca tcgaggagcg cctgccgcag
     6421 tggggcatcg gcgccgaggt gcaggggcgc gagaagcacc tctacggcat ctaccgcaag
     6481 atggccgaga aacgcctgtc cttctcgcag gtgctcgaca tctacggctt tcgcgtcatc
     6541 gtcaaggacg tgccgagctg ctacctcgcg ctcggtgcgc tgcactcgat gtacaagccg
     6601 gtgccgggca agttcaagga ctacctcgcc atccccaagg ccaacggcta ccagagcctg
     6661 cacaccacgc tgatcggccc cttcggcatg ccggtcgaag tgcagatccg cacccgcgag
     6721 atgcaccaca tcgccgagac cggcgtggcc tcgcactggc tgtacaagga agacgagaag
     6781 acgctcaccg agctgcagca gaagacgcac tcctggttgc agtccctgct cgagctgcag
     6841 tcggcctcgg gcgaggccac cgagttcctc gagcacgtca agatcgacct cttccccggc
     6901 gaggtctacg tgttctcgcc caagggcaag atcttctcga tgcccaaggg ctcgaccccg
     6961 gtcgacttcg cctacgcggt gcataccgac gtcggcaatc gctgcgttgc ctgccgcatc
     7021 aacggcgacc tgatgccgct gcgcagcgag ctgcgcaatg gcgaccaggt cgagatcatc
     7081 accgcggcgc aggccaaccc caacccggcc tggctgtcct acgcgcgcac cggcaaggcg
     7141 cgcgcgcaga tccgccactt catgaagaac gcgcagcagg acgagtcggt tacgcttggc
     7201 gagcgcctgc tcaaccaggc gctgcgcccg cacgggctca ccctcgggca gatctccagc
     7261 ttcgcctggg accgcttcct gcgcgaccgc ggcgtgcgcc acaagaagga ggtcttctcc
     7321 gacctcgggc tcggcaagcg cctgccggtc atcgtcgcgc gccgcctcgc cgaggcgcag
     7381 gacctcgagt ccggtcgccc ggacgtggtc aagcccaagc cggcgggggc gatcagcatc
     7441 cgcggctcgg agggtgtggc ggtgcagctg gcgcgctgct gccatcccat cccgggcgac
     7501 ccgatcatcg gcacgctgcg caagggccag ggcctcgagg tgcacaccca cgactgtccc
     7561 aacgtggcca agctgcgtgg cgaccgcggg cgctgggtcg atgtggaatg ggaacacatg
     7621 gtcgacgacc gcctgttcga cgtcggcatc cgcgtgctca gccacaacgc gcgcggcgtg
     7681 ctggcgcggg tggcgagcgc gatcgccgag gaagacagca acatccagag cgtcagcatg
     7741 gatggcgggc agggcgagta caccgcgctc aacttcaccg tacaggtgcg cgaccgcatg
     7801 cacctcgcgc gcgtgatgcg cggcgtgcgc cgggtgcagg aggtcgtgcg catcggccgc
     7861 gtcaaggccg acggccgtgt cggctgaggg ccccgcggcg cgccgacgct gctagaatgc
     7921 gcgccgaccg cggcgcttcg gtggcgccgc acgtgaaccc accggggacc cgacatggcg
     7981 atgtacgaat ccgatcacac caagttcatg cgcgagtgga tggagaagca tccggagcag
     8041 cgcgacgagc agaagaaggg tcgcgccctg tggtgggaca agccgcagag cgtcgaggag
     8101 cagaagcgcg tcgccaccgc ccgcgtgccg gtcaagccct actactacga catcaacaac
     8161 tgatccggcg caccgcgccg gagccggcgc ggccgtccca acggcgccgc ccgttccggc
     8221 tgcggcgccg catgcatccg ttgaaacctc gcctccggcg ttgcggcagg cccgcatgag
     8281 cctgccgagt cgtctcgcct tcatcgatgt cgagagcacc ggcgcgcatc cggtgcgcga
     8341 ccgcatcacc gagatcgcca tcctgcgcgt cgaggacggc gaggtggtcg cgcgctggga
     8401 gagcctggtg gcccccggcc agcccatccc gccgctgatc gaggaggtca ccggcatctc
     8461 cgacgccatg gtcgccgacg cgcccgcctt cgaggcggtg gccgacacgg tcgccgcgct
     8521 gctcgagggc tgcgtcttcg tcgcccacag cgcgcgcttc gactacggct tcatccgcaa
     8581 cgcctttacc cgcatcgggc gcgagttcga ggcgccggtg ctgtgcaccg tcaagctgtc
     8641 acgcgcgctt tatccggaac accaccgcca cggcctcgat gcgctgatcg agcgccacgg
     8701 cctggtctgc tccgcgcgtc accgtgcgat gggcgacgtc gaggcgttgt ggcagttcgt
     8761 gcgcgtgctg gaggccggct tcgagcccga ggtgctggcg cgcgccgcca cgcgcgcgat
     8821 gaaggcgccc gcgcagccgc ccgggctgcc cgaaggcttg ctcgaggcgc tgcccgacgc
     8881 ccccgggctg tatctcttcc acgcccagcc cgagccgccg ccgctgggcg cgcgcgaccc
     8941 ggcgctcttc gtcgggcgcg cacagagcct gcgcgcgcgg gtgcgcgagc acttcggcgc
     9001 gggcgcgcgc aagggccgcg acgccgaact ggcggcgcgg gtgaagcggg tggagtgggt
     9061 cgagaccgcc ggcgaactcg acacttcgct gcgcgagaac gccctgctgc gtgcgctggc
     9121 gccgccctac aaccgcccgc aggagcccgc cggggccgcc ttcgcgctgc gcctgctgcc
     9181 caaccggagg cgtgcgccga tttacgagac ggtggcgatc gccggcaccg acccggcgga
     9241 ttggcacggg ctccacggcg tcttccgcaa ccgtcgcgag gccgacaacc tgctgcgcga
     9301 gctggcgctg ctgtaccggc tgtgcccgcg ccggctcggc ctggagggcg gcaacggccc
     9361 gtgcaccgcg tacgcctcgc gacgctgcgc gggcgtgtgc gcccgccgcg agacacccga
     9421 ggagcacgac gcccgcctcg ccggcgcgct cgccggcgtg ggggtgcggc cgtggccgtg
     9481 ggcggggccg gtggtggtgg aagaggcgcg cgcgcacggt ccgcgccggc tgcaggtgtt
     9541 cgaccgctgg tgccacctgg gcagcgcgca ggacgaggcc ggcgcgctcg ccctcgccac
     9601 ggcgccgcgc gccttcgacg cggacgtctg gcgcatcctt gcgcgctggc tggcggtccc
     9661 ggcccatctc gcgcaggtgc gcgaactcgc ggcgcaggcc gacgaggagg cgcccggcgc
     9721 ggcctagtgc gctgcgcagt cgcgcagctg cgacagcttg ctcagcacca tgccgcggcg
     9781 gccgcgcggc tggatcatgc cgtcgcgggt gagctgcgag aggatgcgcg acagcgtctc
     9841 cggggtcagg ttgagctggg cggcgatggt ctgcttgtcg atgtcgaggc ggatctccca
     9901 gcgctcggca tcgtccggcg cgagccgcgt caggtagtgg gcgacgcgct gcgtgccgct
     9961 gagctggaac tgaacctgca tggtcgacat cagatcgtag ctggcttccg caagccggtt
    10021 gctcatcgac accgaaaagg cggttgagct caccatggcg ttgcgcagcg cggcggtcgg
    10081 caccagcagc agctcggtcg cgctgatcgc ctgggcgttg gcgacgtggg ggcggttgat
    10141 cagcgcggcc tcctcgccga agaagctgcc gggctcggcg agacggacga tcttctcgcc
    10201 gcccgagggc gagagcacga agcatttcac ccgtccgtcg agcaccaggt agatgccgcg
    10261 cggacagtcc tcctgctgga cgaggagttc gccgcgggcg gcgtggatcg gtcgtgcggc
    10321 agcgagcacg cgctcgcggg cgcaggcgtc gagcatgtcg aagggagcga agcgggcgag
    10381 caggtcgctg gcgtcggggg cgagggaggg gggcctgcag ctcatgcgga tctcctgcgg
    10441 acgtcggcgt ggtcttccag tcgctagact agccgctggt tttcaccctg catggcatcg
    10501 cggagcgcgt gcgtgcctgc ggaatacctc cgaagtggta cttacggatt tctgcaaggc
    10561 actgaaagat atattcaaag ggctggatcc ggaggcgctc cggccctcga tcgaagtgga
    10621 aggggtatgt ccacgttgtt gtcccggatt ctttccggat ggagattcga catgcacctg
    10681 gcggttcccc gccggctcgt gaggcgctcg atcatgctgc tggtgtcggt cgccctggta
    10741 gcgatgacgc tgatcgggct ggccggcatg agcgcgtcct tcctggtggt cgatcgcagc
    10801 cgcgacagcg tgcgggcgat cgatgtcgcc ggaagcttgc gcagccacac ccggcgcatc
    10861 gccaacctca tcgccatcga cgcgctcaag ggccgcgtcg gcgtgtccga gcgcacgcgc
    10921 gcggcgatgg ccgacatcga gcgcgagctc caggagccgg cgctgcgccg cttcggggac
    10981 gcggcgccgg gcgagctctt cgcggccacc taccgcggcg tgcaggcggg ctgggagcgc
    11041 acggtgaggc cgcggatcga ggcgctcgac gggcatgggc cgcccgacgc acgcgagatc
    11101 gaggcgctgc tcgcaggggt ggacgacttc gtcggccagg tcgatagcct ggtcgcggtg
    11161 ctcgggcagg agaacgagcg ccgcatcgac gagctgcgcc gcatcctcgc gctcgccgcc
    11221 gcggtcacgc tgggggtggt gctggtggtg atcgtgctct tgcagcgcgc gctgctgcgc
    11281 ccgctcggcg gcctgctcga cgccgcgcgc cgcatcgccg gcggcgactt cggcgtgcgc
    11341 gtgcgttaca ccggcgagga cgagctcggc caggtcggca gcgccttcaa cctgatggcc
    11401 gacgagctcg cccgccacta ccatctgctc gagcagcgcg tcaccgagaa gaccgccgag
    11461 ctgcagcgca gcaaccgctc gctggagctg ctctaccacg ccattgcccg cctctaccag
    11521 gcgccgagcg cgcccgatgc ctacgatgcg accctgcgcg acatcgaccg cgtcgccgga
    11581 ctggagggtt ccttcgtctg catcgagccg cgccccgggg ccccggcggc ggtcatcgct
    11641 tcgtccatgg gaccgtgtcc ggaccgagcc gagcgtggcg aggatgcctg cgccgcctgc
    11701 cgggcgggct cggaggggca ggcgctggcg ctgctgtcgc cgaccctgct gcgctttccg
    11761 ctgcgcgacc gcgagcacca ttacggcatg ctgcgccttt cgctgcccga cggcgcgcgc
    11821 ctggaggact ggcagcgcca gctcgtcgag gccttgtcgc gccacatggg catggcgctc
    11881 ggcgcggcgc ggcgtacgga gcaggagcgc ctgctcgcgc tccaggagga gcgctcggtg
    11941 atcgcgcgcg agctgcacga ctcgctcgcc caggcgctgt cctacatgaa gatccaggtc
    12001 agcctgctgc agcgcgcgct cgccgacccg gcgcgcgcgg ccgaggcgga gccgatcctg
    12061 gccgacctgc gcgagggcat cagcgccgcc taccgccagc tgcgcgagct gctggtgtcc
    12121 ttccgcctcg gcctgtcggc cgacctcgcc accctgatgg aggacgccgc gcgcgaatac
    12181 ggcacccgcg gcgggctgga ggtggcgctc gcggtggagc tcggcgcctg ccagctcggc
    12241 ccgaaccagg aggtgcacgt gctgcagatc gtgcgcgagg ccttgtcgaa catggtgcgc
    12301 cacgctgcgg cgcggcatgc ctgggtggag ctgcgcggcg gcgcggacgg cgaggtgcgg
    12361 ctggaggtgc gcgacgacgg ctgcggcatc ggcgcgccgc cggcggatgc gcgcaaccac
    12421 cacgggctgg cgatcatgcg cgagcgcgcg cgcagcatgg gcggggagat cgagatcggg
    12481 ccggcgttgc ctagcggcac gcgggtgtgc gtgcgcttcc gggccgccaa cgcgggcgtg
    12541 gcggcgatgg tgcaggggga tgcgaagaag gaaatggagc catgaacgag agctgtcgcg
    12601 tgctgatcgt ggacgaccac ccgctgttcc gtcgcgggct ggtgcagctg ctgcgcacga
    12661 ttcccgcctt cgtcctcgtc ggcgaggccg ccagcggcgc cgaagggctt gtgctcgcgc
    12721 gcgagctgcg ccccgacctg atcctgctcg acctcaacat gcgcgacggc gacgggctcg
    12781 acatgctgcg cggcctgcgc acggcgcgca gcgaggcgcg cgtggtgatg gtcacggtgt
    12841 cggactcggg cgaggacgtg gtggcggcgc tgcgcggcgg ggtcgagggc tatctgctca
    12901 aggacatgga gcccgaggcc atgctcgagg cgctgcagga cgtggccgcc gggcgggtgg
    12961 tgatcccgcc gcagctcaac cacctgctcg ctgcggcgct gcgcggcgag tcgcggccgc
    13021 agtctgcggg cgccgccgga ctcaccgagc aggagctgcg catcctcgag aagatcgccg
    13081 ccgggctctc caacaagcag atcgggcgcg agctcgacat cgccgagggc acggtcaagg
    13141 tgcacgtcaa gcacatcctg cgcaagctcg agctgcgctc gcgcgtcgag gccgcggtgt
    13201 gggcggtgga gcacctgcgn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    13261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnc
    13321 ggaacttctt cttcggacgc acgcgcgcag tcgaacccgc actccgcccg ccctgggcgc
    13381 tggaggagga cgattttgtc gcacgctgca cgcgctgcga ccgctgcatc gaggcctgtc
    13441 ccacgagcat cctggtacgc atggacggcg gctttccggg agtggacttc ggtcgcggtg
    13501 agtgcacctt ctgcggcgac tgcgtcgcgg cctgcgaacc ccgcgcgctg caacgcgacg
    13561 ccaccaccgc gccctgggac cgcgtcgcgg tcatcggcga ggcttgcctg gccgcgcgcg
    13621 gcgtcgagtg ccgcgtgtgc ggcgagtcct gccccgaagg cgccatccgc ttccgtcccc
    13681 gcctcggggg cgttgcccat ccccagctcg acgccgccgc gtgcaccgcc tgcggcgcct
    13741 gcatcggccc gtgcccgacg cgtgcgatcg acacgcgcgc gcgcgaatcc ctccccacgg
    13801 agagcgaaac atgaacattg caagtctggt cgtgcgggcc tttcccgcgg atttccccga
    13861 agtcgtcgag ggcctgaaga aggtgcccgg tgtcgagttg cacgggcagt ccgcagagaa
    13921 gggcaacatc gtcatcacca tcgaggacgg cgcgggctgg tcggtgaccg actcgatcct
    13981 ggcggtgaac ctgctgccca aggtgcaggg gctgacgatc gcctacgaat acaccgatga
    14041 aggtctggaa ttgacggagg tctgacatga gcatgaatcg acgcgaattc atcaagaaca
    14101 acgcgatcgc cgcggcggcc gccaccgccg gcatcggcat cccggtcgtc gccgaggcgc
    14161 agcagcccgg cgcgggcagc accaaggtgc gctgggacaa ggccgcctgc cgcttctgcg
    14221 gcaccggctg ttcggtgctg gtgggcgtgc aggacgggcg cgtggtcgcc acccagggcg
    14281 accccgactc gccggtcaac cgcggcctga actgcatcaa gggctacttc ctctccaaga
    14341 tcatgtacgg cgaggaccgc ctgaccaagc cgctgctgcg catgaagaac ggccagtacg
    14401 acaagaacgg cgagttcacg ccgatctcgt gggaccaggc cttcgacatc atggagcaga
    14461 agtggaagaa ggcgatcaag gagcacggcc cggattccgt cgccatgttc ggctccggcc
    14521 agtggacggt gtgggagggc tacgccgcct ccaagctcat gaaggcgggc ttccgcacca
    14581 acaacctcga ccccaacgcg cgccactgca tggcctcggc ggtggccggc ttcatgcgga
    14641 ccttcggcat cgacgagccg atgggctgct acgacgacat cgagaacacc gacacggtcg
    14701 tgctgtgggg ctcgaacatg gccgagatgc accccatcct gtggagccgc atcaccgacc
    14761 gccgcctgtc caaggaaggc tgccaggtcc acgtgctgtc gaccttcgag catcgctcct
    14821 acgagctcgc cgacaacccg atgatcttcg tgccgcagac cgacctggcg atcctcaact
    14881 acatctgcaa ccacatcatc caggccggca aggtcaacaa ggccttcgtc gagcgcaacg
    14941 tcaagttcaa gatcggcgaa ggtgacatcg gcttcggcct gcgccccaac cacccgctcg
    15001 aggccaaggc caccagcaac ggctatccgg gcgcggacgg caagcccaag ggcgacactg
    15061 gcgcggcgaa ggactgcagc ttcgacgatt tcgccaagtt cgtctcggaa tacactctgg
    15121 agaaggtctc caagctctcc ggcgtgccgc aggatcgcct gctcaagctc gccgagcagt
    15181 acgccgaccc caaccgcaag gtgacgtcgt tctggaccat gggcttcaac cagcacaccc
    15241 gcggcacctg ggtgaacaac atgatctaca acgtccacct gctggtgggc aagatcagcg
    15301 agcccggcaa cagcccgttc tcgctcaccg gccagccctc ggcctgcggc accgcgcgcg
    15361 aggtcggcac cttcgcccac cgcctgcccg ccgacatggt ggtgatgaac ccgatgcacc
    15421 gcgcgctcag cgaggagatc tggaagctgc ccgagggcac gatctcgccc aagatcggct
    15481 atcacgcggt ggcgcagagc cgcgcgctca aggacggcaa gctcaagtgc tactggacct
    15541 cgaccaccaa caacatgcag gccggtccca acgtcaatga cgagatctac ccgggctggc
    15601 gcaatccgga agccttcgtg gtggtgtccg acgtctatcc gaccgtctcc gcgctgtcgg
    15661 ccgacctgat cctgccgtgc gcgatgtggg ccgagaagga gggcgccttc ggcaacgccg
    15721 agcgccgcac ccagttctgg cgccagcagg tgtcggcgcc gggcgaggcc aagtccgacc
    15781 tgtggcagta catccagttc gccaagcgct tcaaggtcga ggacgtgtgg ccggaggagc
    15841 tcatcgccaa gaagcccgag taccgcggca agaccctgta cgacgtgctg tacgccaacg
    15901 gccaggtgaa caagttcccg ctcgaggacg tcgagaaggc caacggccac gcctgggccg
    15961 gctacatgaa cgacgagtcg aaggagctcg gcttctacct gcagaagggc ctgttcgagg
    16021 aatacgccgc cttcggccgc ggccacgccc acgacctcgc cgacttcgac gtctatcaca
    16081 aggcgcgcgg cctgcgctgg ccggtggtcg acaacaagga gaccctgtgg cgcttccgcg
    16141 agggctacga cccgtacgtg aaggccggcg agggcgtgaa gttctacggc tacaaggaca
    16201 acaaggcgat catcttcgcg ctgccctacc aggatccgcc cgagatgccc gatgccgagt
    16261 tcgacatgtg gctgtgcacc ggccgcgtgc tggagcactg gcacaccggc tcgatgaccc
    16321 ggcgcgtgcc cgagctgcac cgctcggtgc ccgacgcgca gatcttcatg cacccggagg
    16381 acgcgcagaa gcgcggcctg cagcgcggca tggcggtcaa ggtggtgtcg cggcgcggcg
    16441 agatcgtcgc ccgcctggag acccgcggcc gcaacaagcc gccggtcggg ttgatcttcg
    16501 tgcccttctt cgacgagggg cggctggtga acaagctcac gctcgacgcc acctgcccga
    16561 tctcgaagga gaccgactac aagaagtgcg cggtgaaggt ccttaaggct tgatgagagg
    16621 aggcgcgagt cccgcccccc gccgaccggg gggacgtgcg gagggcgggg ctcgcgatgg
    16681 cgatgaacga caaggtgcaa tcgagcggac gcgctgaacc cgtcgctccg gcttcgcgcc
    16741 gccgcttcct caaggatgcg gcgggcgttg ccgggggtgc gggcctgctc gcgctcggtg
    16801 ccgggatgta cgcgaagcag gcgtcggcgc tgccggccac tgccatccgt ccgcccggtg
    16861 ctctccccga agacgatttc ctcgcggcct gcgtgcgctg tggcctgtgc gtgcgcgact
    16921 gcccctacaa gaccctcaag ctggccgagc tcggcgacgg ggtggcgacg ggcacgccgt
    16981 atttcgaggc ccgcgacatc ccctgcgaga tgtgcgagga catcccctgc gtggtggcct
    17041 gtccgaccgg cgcgctcgac cgcgcgctgg tcgacatcgc caaggcgaag atggggctgg
    17101 cggtcctgat cgatcaggag aactgcctca acttcctcgg cctgcgctgc gacgtgtgct
    17161 accgggtgtg cccggtcatc gaccaggcga tcaccctcga gcgcatccac aacccacgct
    17221 ccgaccgtca cgcgatgctg ctgccgacgg tgcattccga gtactgcacc ggctgcggca
    17281 agtgcgagaa ggcctgcgtg ctgcccggcg agtcggcgat caaggtgctg ccgatcaagc
    17341 tggcgcaggg ctcgaaggcc gagcattacc tgcgcggctg ggaggagaag gaagccgccg
    17401 gcaagtcgct gatcggcgac caggtcgagc tgccggtgcg cggcctcgag ggcaaggcct
    17461 acggcgacac ccgggtcgag cccgggcagg ggccggtcca ggggggcacc caggtgccgg
    17521 attacgcgcc cgcgaagccg gcgggcggcg gtctcgattc ggggtggaag ccatgagcgc
    17581 acatgcgagc tccggcgccg cgccggaacg caaggtcccg cccaccagcg tgcgcggcgc
    17641 cgcgatgcgc ggcgtggtcg cgcgtcccgg gcgcgaggcg gtggaggcca agggctggct
    17701 gcgcgcgcac aagtggctgc tgctgcggcg cgcgtcgcag ctcggcatcc tcgcgctctt
    17761 cctcgtcggg ccgtggctgg gctggtggat cgtcaagggc aacctgtcgt ccagtctcac
    17821 cctcggcgtg ctgccgctca ccgacccctt cctggtcgcg cagcagctcg ccgccgggca
    17881 gtggccctac caggaggcgc tgctcggtgc cggcatcgtg ctcgccttct acctgctctt
    17941 cggcgggcgg ctgttctgct cgtgggtgtg cccggtcaac ctcgtcaccg atgccgctgc
    18001 ctggctgcgc cggcgcctgg gcctcaaggg cggcaaggcg ccctcgggca gcacgcgcta
    18061 ctggctgctc ggcttcgtgc tggtgatcgc ggcggcgacc ggttcgctgg cgtgggagtg
    18121 ggtgaatccg gtgtcgatgt tccaccgcgg cctgatcttc ggtttcggcc tggcctgggg
    18181 catcgtcggc ggcatcttct tctacgacct gctcatcgcc ccgcgcggct ggtgcggcca
    18241 cctgtgcccg cagggcgcct tctacgccct gatcggacgc gccgccgtcg tcaaggtgtc
    18301 ggcggacaag cgcagcgcgt gcaacgactg catggactgc ttcgccgtgt gccccgaacc
    18361 ccaggtcatc cggcccgcgc tcaagggcgt cggccaggac catcccctca ttctggatgc
    18421 cgactgcacc acctgcggac gctgcgtgga tgtgtgcggc aaggacgttt tccgcattac
    18481 gacccgattc aacaggagcg agtcatgaaa aaacaaaccc gaaatctggt gctcgcgctc
    18541 gtcgccgctg tcggcttcgg tgccgtggta ccgcccgcgg cgatggcgca ggcggtgaag
    18601 agcatccgcg gcgccgacgt ggccgagcag gaactgcagg tcggcaacta caagccgatt
    18661 cccgaccagg ccccgatcga tcgcgactac gtgcagcaac cgccgctgat cccgcacaag
    18721 gtggagggtt acgaggtcac gctcaacttc aacaagtgca tggactgtca cgcctggagc
    18781 cgctacaagg agtccggcgc caccaaggtc agcctgacgc acttcaagga tcgtgacggc
    18841 ggtgaactgt cgaacatctc gccgcgccgc tatttctgca tgcagtgcca tgtgccccag
    18901 accgacgcca agccgctggt cgccaacaag ttccagcgcg cggaaggcct gcgctgaaga
    18961 atcgacacac ggggatcgtc atgaccgaca acaacaagag cctgatgcag cgcatccgcg
    19021 gtgcgggctg gggcgccatc gtcctgctcg tcgccgcggg cgtggtgttc tggggcggct
    19081 tcaactgggc cctggagatg accaacacgg agaagttctg catctcctgc cacgagatgg
    19141 aggacaacgt cttcaaggag taccgcaaca ccatccacta ccagaaccgc accggcgtgc
    19201 gcgcgacctg cccggactgc cacgtgccca aggagtgggg gccgaagatg atccgcaaga
    19261 tcaaggcctc gcgcgagctc tacggcaagg tgatgggcac catcgacacg ccggagaagt
    19321 tcgccgccga gcgcctgcgc ctggcacaga acgagtggac ccgcatgaag gcgaacaact
    19381 cgcaggagtg ccgcaactgc cacaactacg agtacttcga ctactcggtg caggggcgtc
    19441 gctccaacca gatgcaccag gccggcttcg ccgagggcaa gacctgcatc gattgccaca
    19501 agggcatcgc gcactcgctg ccgccggtcg accagcacat cggtgcgccg cgtgaaggcg
    19561 tcgcccccga ggtgatgcat ccgccggtga agaaggactg ag
//
LOCUS       DAOTIN010000056        19494 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_3363_length_19494_cov_9.180565, whole genome shotgun sequence.
ACCESSION   DAOTIN010000056 DAOTIN010000000
VERSION     DAOTIN010000056.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 19494)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 19494)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19494
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3363_length_19494_cov_9.180565"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            6..353
                     /gene="msrB"
                     /locus_tag="P5537_09850"
     CDS             6..353
                     /gene="msrB"
                     /locus_tag="P5537_09850"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018607684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HRV78385.1"
                     /translation="MPAVDAGFVRESTAVNSEYWDVWEKGAYRCVCCGAPLFRSEHKF
                     DAGCGWPSFWTAAEPDNVETAEDRSHFMLRTEVLCHQCGAHLGHVFEDGPQPTGLRYC
                     INSASIKLEKDAE"
     gene            complement(486..1667)
                     /locus_tag="P5537_09855"
     CDS             complement(486..1667)
                     /locus_tag="P5537_09855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011238757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase family protein"
                     /protein_id="HRV78386.1"
                     /translation="MANREVVVLSAVRSAVGGFGGSLKDMEPSDLGAVVIKEAIARAG
                     VDPKAVSFASVGHCIPTDSRYAYVSRVATINAGMSMDSVAFQVSRLCGSAQQAIVSSA
                     QAIMLGDADFAIGGGVEVMSRGAYLLPALRSGARMGDTKAIDSMVAVLTDPFGVGHMG
                     ITAENLCTKHGITREEQDAFALESQKRAAAAIAEGRFKGQIVPITFETRKGTVVFDTD
                     EHPRMTTMEALGKMKPAFKKDGSVTAGNASGINDAAAFLVLADAAKAASAGHKPIARL
                     VSYAIAGVPNEVMGEGPIPATKLALQRAGLKLDQIDVIESNEAFAAQSITVNRGLGLD
                     TAKVNPNGGAISLGHPVGATGSVIITKLLHELIRVNGRYGVATMCIGGGQGITTVWER
                     V"
     gene            complement(1697..2620)
                     /locus_tag="P5537_09860"
     CDS             complement(1697..2620)
                     /locus_tag="P5537_09860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CobD/CbiB family protein"
                     /protein_id="HRV78387.1"
                     /translation="MTFFSLILALVLEQLRPLPARGWTVRGVRGVVEGVRARFDAASA
                     AQGRVAWLLLVPTAAFASAFGFWLLWEMHPALAFLFNVVVLYLCIGFRHDTRFFSAIH
                     VALRLGEPEGARSLLEDWRGTRHDGASANEIARLAIEEALVVSHRRLFGVMFWFVLLP
                     GPSGAVMYRLAGLLAEEWGGRDAGAAGFGRFARGAREAIEWLPVRITAIVFSIMGNFE
                     DAIYCWRSQAVLWPERSSAILIASGGGALGVRLGMPVHEAGELLDRPEMGLGSEAGVD
                     HMQNTVSLLWRALLVCLFLLFLLAVAGWAGR"
     gene            complement(2733..3356)
                     /locus_tag="P5537_09865"
     CDS             complement(2733..3356)
                     /locus_tag="P5537_09865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004356458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0010945 - CoA pyrophosphatase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HRV78388.1"
                     /translation="MNPGSARHGLPALERIRLRLAEGPRGEGEFNGDGRDLARSRPPK
                     PAAVLVPLVVRSEAPSVLLTRRTDHLHHHPGEISFPGGRLEESDPSPAHAALRETEEE
                     IGLARRHVELIGALPDYFTGTGFRVTPVVGVVHPPLELTLDAFEVAEAFEVPLAHFLD
                     PRNHQEHSILHEGRMRRFHAMPWHGYFIWGATAGILMSLYRMLQDEA"
     gene            complement(3365..4000)
                     /locus_tag="P5537_09870"
     CDS             complement(3365..4000)
                     /locus_tag="P5537_09870"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011765912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02281 family clan AA aspartic protease"
                     /protein_id="HRV78389.1"
                     /translation="MKRSCALLLGGVCLASPALALDVVMAGALGNKAVLVVDGAAPQT
                     IRVNEATREGVRLRALAGQTATLEHDGRTFQLRVGEHAASAPGASVAEASLVSDGGGH
                     FFADASVNGRSVRVLVDTGATLVALGRNEAVRLGIDYRSGQPGQSETANGTARVWRVK
                     LDSVELKGMRLYGIEAAVHESELPYVLLGMSFLGRMDWRREGDRLLLKKRY"
     gene            complement(4095..7574)
                     /locus_tag="P5537_09875"
     CDS             complement(4095..7574)
                     /locus_tag="P5537_09875"
                     /inference="COORDINATES: protein motif:HMM:NF017388.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilC/PilY family type IV pilus protein"
                     /protein_id="HRV78390.1"
                     /translation="MSFKRLNSDSGRSACANPRVSRVRLLKRLFLGLCVATAANGAEV
                     EIADTPIPTGGAIQVKPNIMFVLDDSGSMEWTYLPDAASYPPYWVRSKKGFEVVRPYG
                     FASPACNGMYYDPAVKYVPPVKADGTSYPAASFTAARKDGFDGASAVVDLSKDFRAAD
                     WDCGSADGGRCDPKEAAYYYKYKRPNKGPLPLEYVYKANGSLDTGAGIYKYCNLGIGT
                     SDVFEKVTSSATGFDKQNFANWYSYYRSRINAMKSASGRAFGQLLNPDGLRIGFSTVS
                     ETGVTADDRGRFQPLGDFCAAGSDKCSPDNQRSEFFRMLYKTPADAWTPLRGSLAKIG
                     RMYAGFDGSSRLSASDDPVQYSCQQNFVIMATDGSWNQDKNVPFNIANSGGVGDRDGD
                     APRPMLDAYKVKNSLADIAMYYYETDLRDASLGNCTGRIEGEDVCFNDVQGGGRDEKA
                     STQHMTTFTLGFGIDGLLKYTENYETGLELDYSAILGGSKNWPDPRTTETNETATFIE
                     RVDDLWHAAVNGRGAYFSAKTPDAVVSGLVRALNTAAARTGAGSGAATSSLEPVAGDN
                     YAYVASYRTQHWDGDLQAREINLRSGTLASEPDRMWSAQAKLDELAAGTGWSSRKIYM
                     KGSGKTRLDFTASNVRSVHSSLPDALTNDVIDFIRGDSSKEDQAGNATRTLRDRLHVL
                     GDIVSSHPVFVRRPPYKYSDSGYADFVTAKSARAGIVLVGANDGMLHAFDADTGTERW
                     AYVPSAVIPNLHKLAHKDYGKTSGVPHQYYVDGAIAVGDICVADDCDDAGASDWRTIA
                     VVGLGKGGRSYFALDITDTTNPSILWEFGNADDSDLGLAFANPVITKHGGKWVVLIAS
                     GYNNASTGDGKGRLYVLDAESGDKVSEIVTDNESDPSKSGIARVSNWVDNIRLDDTTR
                     YAYAGDLSGRLWRFDLTAETATLLASFGSTQPITTRPELAEVKASDGTLKRVVFVGTG
                     KYLGQGDLDDASVQSIYAVREPLADTGWGNFRAAAGVVQQVITASGATRTITEESVDW
                     TTGPGWFVDLSAEAGERINVDFKIVSGVLTAVTNVPEREACTVGGRSYLYFFDYRTGS
                     SVETVEGLKVGELLTQALGVGLAVIRLEGKEVAIINTSDNRQISLPVPPASLSGTFRR
                     FMWRELVTEQPGQ"
     gene            complement(7587..8255)
                     /locus_tag="P5537_09880"
     CDS             complement(7587..8255)
                     /locus_tag="P5537_09880"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78391.1"
                     /translation="MNLHDRNQPRVQRGIVLFTVLIALVVLSLASVALVRSIDTGTTI
                     AGNLAFRQAATQAGDAGTEAALAWIQGQIAANGGIVLQTSKASGYYATSRSGCDLTGG
                     LTASTADNVRWEAGDPDNPDCNMVAAAVADNLLPPGYTATYVINRMCNADGPPNGTSP
                     GGVTVACEMYTRTSAAAEDGRSMTNVGYHATNAQSSQLLYRVTTRVAGPNNAVSHVQV
                     VLAN"
     gene            complement(8266..9327)
                     /locus_tag="P5537_09885"
     CDS             complement(8266..9327)
                     /locus_tag="P5537_09885"
                     /inference="COORDINATES: protein motif:HMM:NF027400.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0043683 - type IV pilus assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilW family protein"
                     /protein_id="HRV78392.1"
                     /translation="MGRNSAQRGLTLVELLVGLATGLVVLLVASQVMQAFEGQKRTST
                     GGNDSQTNGALAVYLLEQEIRMAGYGLFGPEGAYCRNGINIYKNNGAAGEVVMNALSL
                     VPARIIDGGDGADSIVLMRSDGAADALPLSIVKNMPNPSSIVTVGSDGGLQEGDLVVL
                     GDRGGNKVCTVMQLSQPPKNTGNGVNLVHNSGNGSPYNPKDPFPVAYVVGDIAFRYGD
                     GTSFGRRFSVRCDHLVESDPVDVADAAVTCANSTPMVAQVVDLQAEYGVVDGGALTWR
                     SATGDWAALDADETAQIRAIRVGVVTRHPQFEKTAVPAAQAPAWMGEATTDLIAANPN
                     YRHRVFETVIPLRNVVWAP"
     gene            complement(9339..9731)
                     /locus_tag="P5537_09890"
     CDS             complement(9339..9731)
                     /locus_tag="P5537_09890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014238497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78393.1"
                     /translation="MGMRASRRPRGARGIILLEVLISVLVLAFGVLGIIGLQAAAIQH
                     TTSAKYRTDASFIANARIGEIWAGPNAPGTFGEADTDVSAAFPGASLPNGKRTTTIAG
                     ERVTVTVTWQAPGADRVSNVVVVAHVAK"
     gene            complement(9734..10273)
                     /locus_tag="P5537_09895"
     CDS             complement(9734..10273)
                     /locus_tag="P5537_09895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015627 - type II protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GspH/FimT family pseudopilin"
                     /protein_id="HRV78394.1"
                     /translation="MKSKSFLVNARRCALERGFSLVELMVTVAVLSLLMTLAVPSFNE
                     WIQNGRIRTAAESIQNGLQVARAEAVRRNARVEFALVGTGGGWVVRFAGGGATIQARS
                     GSEGAGGVVVSAVPDDATTVVFDGLGRADNTLTQIDIDVPTSALPAAQSRDLRITIGT
                     GGVRMCDPNVSGSTDPRKC"
     gene            complement(10322..10756)
                     /locus_tag="P5537_09900"
     CDS             complement(10322..10756)
                     /locus_tag="P5537_09900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004356473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0043683 - type IV pilus assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilin protein"
                     /protein_id="HRV78395.1"
                     /translation="MKTTAQAGFTLIELMVTVAILGILASIALPAYNDYLVKGRIPQA
                     TSGLANGRVLLEQWFQDNRTYKAVPTEGGGDSSPPCPANTQYFTFSGCPSESATTYTL
                     TATGTGAMSGFVYTINESNTMTSTTSWGDSGNCWVVSKNGGC"
     gene            11071..11697
                     /locus_tag="P5537_09905"
     CDS             11071..11697
                     /locus_tag="P5537_09905"
                     /inference="COORDINATES: protein motif:HMM:TIGR02595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-CTERM sorting domain-containing protein"
                     /protein_id="HRV78396.1"
                     /translation="MKTKTLIGALAATSLSFSAHATLIDFDSLTSGQEFTTYSGLTWT
                     NMVALDPSSSPEFADTGYVSGVQSPKNIALNFAGSPASVTSNDGFRLNSGYFTSAYYN
                     GLTLDFIGTAGGTKLSKTVMLSLQPLFVEFDDRWNIDTLQMATTCDTTADCKPISENV
                     AGKFNFALDDLRIDESTSTVPEPGMLALLGGGLLGMTLIRRRRGASAS"
     gene            complement(11699..11890)
                     /locus_tag="P5537_09910"
     CDS             complement(11699..11890)
                     /locus_tag="P5537_09910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjfB family protein"
                     /protein_id="HRV78397.1"
                     /translation="MDASAIAAMASNNALAQVQQEASVEVLRKALDLQGQSAMQLLQA
                     IPRPPAVGSTAGGVVDTWA"
     gene            complement(12048..12533)
                     /locus_tag="P5537_09915"
     CDS             complement(12048..12533)
                     /locus_tag="P5537_09915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011765914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HRV78398.1"
                     /translation="MPSFDILSEVDQPALRNAVEQANRKVDGRHDFKGTSAKIELAEK
                     LLTLYGDSDFQLEQIKTILLPEMTKKNVDVRCLDYGDVQKISGNKVKQEVKVRVGVEQ
                     ELAKKIVKLLKDSKMKVQAAIQGDAVRVSGAKRDVLQEAIALVKKQITDFPLQYGNFR
                     D"
     gene            complement(12550..12873)
                     /locus_tag="P5537_09920"
     CDS             complement(12550..12873)
                     /locus_tag="P5537_09920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011765915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HRV78399.1"
                     /translation="MGITAKLDGVAVTTQANVYFDGKCVSHSVQFADGTKKSVGVILP
                     ASLTFNTGAPEIMEGVAGSCRVRLKGAAEWKTYGAGESFDVPGNSSFDIEVAGEPYHY
                     ICHFG"
     gene            complement(12888..13118)
                     /locus_tag="P5537_09925"
     CDS             complement(12888..13118)
                     /locus_tag="P5537_09925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2788 domain-containing protein"
                     /protein_id="HRV78400.1"
                     /translation="MDNEAFILGLTFAEFEDLALKLGLTGLILFMVFIIWNLGKESKA
                     GRYGMMWLFLGLGVGFVGFIAKGIIQKLLGIE"
     gene            complement(13140..14369)
                     /locus_tag="P5537_09930"
     CDS             complement(13140..14369)
                     /locus_tag="P5537_09930"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011765917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HRV78401.1"
                     /translation="MSDVNKVVLAYSGGLDTSVILKWLQDTYQCEVVTFTADLGQGEE
                     LEPARTKALKFGIKPENIFIDDLREEFVRDFVFPMFRANTIYEGEYLLGTSIARPLIA
                     KRQIEIARATGADAVSHGATGKGNDQVRFELGYYALMPGVKVIAPWREWDLLSREKLL
                     AYAEKHGIPIEMKHKQGGSPYSMDANLLHISFEGRHLENPAAEAEESMWRWTVSPEAA
                     PDAAEYIDLEFEHGDLVAIDGKRMKPHELLARLNELGGKHGIGRLDLVENRYVGMKSR
                     GCYETPGGTVLLRAHRAIESITLDREVAHLKDDLMPRYASMIYNGYWWSPERRAIQAL
                     IDHTQQTVNGWVRLKLYKGNVIVTGRDSKTDSLFDPTIATFEDDAGAYNQKDAHGFIR
                     LNALRMRIAANAKAKRG"
     gene            complement(14437..15363)
                     /gene="argF"
                     /locus_tag="P5537_09935"
     CDS             complement(14437..15363)
                     /gene="argF"
                     /locus_tag="P5537_09935"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HRV78402.1"
                     /translation="MSSPIRHYLQFKDFTREEYDYVFARAKWIKDKFKRYEPYHPLFD
                     RTLVMIFEKASTRTRLSFEAGMHQLGGSAIYLNTRDSQLGRGEPVEDAGQVISRMSDL
                     VMIRTFEQDIVERFAANSRVPVINGLTNEYHPCQILADILTFIEHRGSIRGKTVAWIG
                     DSNNMCNTWLQAAEVLDFNVHVSTPPGYEVEPERAGLFGTNHFEQFADPMEACKGADL
                     VTTDVWTSMGFEAENEARMKAFADWCVDADMMSVAHQDAVFMHCLPAHRGEEVTAEVI
                     DGPQSVVWDEAENRLHAQKALMEYLMLGRIES"
     gene            complement(15373..16548)
                     /locus_tag="P5537_09940"
     CDS             complement(15373..16548)
                     /locus_tag="P5537_09940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HRV78403.1"
                     /translation="MSHVMNTYARLPVAFTHGEGVWLYDETGKRYLDALSGIAVNTLG
                     YKHPRLVKAIADQAERVLHTSNLYRIPLQEQLSDRIAEAAGMDEVFFCNSGCEANEAA
                     IKLARMYGHNKGIELPHIIVMESAFHGRTMATLSATGNRKAQAGFEPLVQGFIRVPYK
                     DIEAIRKVGEHNHSVAAVMLEMIQGEGGVNVADEAFQRELRALCDEKGWLMICDEVQC
                     GMGRTGKWFGWQHAGTRPDVMTLAKGLASGVPIGACVTSGLAKGLFGPGNHGSTFGGN
                     PLACAAGLATFDAIVEDKLMDNAVAVGEAIRKGMAEALAGEAGVVDIRGRGLMIGIEL
                     DRPCGVLMARAAEHGLLLSVTSERVVRLLPALTFTTADAQTLVSMLAPMIRDFLANG"
     gene            16853..17143
                     /locus_tag="P5537_09945"
     CDS             16853..17143
                     /locus_tag="P5537_09945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3579 domain-containing protein"
                     /protein_id="HRV78404.1"
                     /translation="MNQKIENFIIVGVTREGKKFRPSDWSDRLCGVMSAFGADHRMTY
                     SPYVRPGCTLKGDKTVLVDARLYDVEPLAYKFMVNFANDNNLQIEWVGDAPL"
     gene            complement(17457..17723)
                     /gene="rpsT"
                     /locus_tag="P5537_09950"
     CDS             complement(17457..17723)
                     /gene="rpsT"
                     /locus_tag="P5537_09950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000312 - plastid small ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HRV78405.1"
                     /translation="MANSAQARKRARQATKARAHNASLRSRLRTAIKAVRKAIVGGDK
                     AAAQSVFRTSMSTIDSIADKKIIHKNKAARHKSRLSAAVKSMAA"
     gene            17893..19431
                     /gene="murJ"
                     /locus_tag="P5537_09955"
     CDS             17893..19431
                     /gene="murJ"
                     /locus_tag="P5537_09955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0034204 - lipid translocation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HRV78406.1"
                     /translation="MNLLRALATVSGMTLLSRILGFVRDLVIARAFGAGMATDAFFVA
                     FRLPNLLRRMFAEGAFSQAFVPILAEYKNRQGEAATHTLVSRVATVLGLVVAVVAALG
                     ALAAPLIIYVSAPGFSGDPGKFELTVELTRITFPYIFFMSLVALAGGVLNTWSRFAIP
                     AFTPVLLNIAFIGMALFAVPWFDPPVLALAWAVFLGGLLQLALQVRPLMKIGMMPRFD
                     LDLADPGVRRVMKLMAPAILGVSVSQISLLINTIFASFLESGSVSWLYYADRLMEFPA
                     GLLGVALGTILLPSLSKLHADDKAEEFSSLLDWGLRLTLMLTLPAALGLALLAVPLAA
                     TLFNYGAFSASDVMQTRSALVAYSVGLTGLILVKVLAPGFYARQDIRTPVKIAILTLA
                     ATQLMNLAFIVPLRHAGLALAIGLASCLNAALLYRGLRKREVYIPQPGWGSFALKLLV
                     ALGVMGATLWFASGPASLWTQIGGLERGLRLALIVLGGVLAYFATLFALGFRPRDFRR
                     RGAA"
BASE COUNT         3153 a         6678 c         6285 g         3378 t
ORIGIN      
        1 gtgccgtgcc ggcggtggac gccggatttg tgcgggaatc gaccgccgtt aacagcgagt
       61 actgggacgt ctgggaaaag ggcgcctacc gctgcgtgtg ctgcggcgcc ccgctcttcc
      121 gctccgagca caagttcgac gccggctgcg gctggccgag cttctggacc gcggccgagc
      181 ccgacaacgt cgagaccgcc gaagaccgca gccacttcat gctgcgcacc gaggtcctct
      241 gccaccagtg cggcgcccac ctcggccacg tcttcgagga tggcccccag cccaccggcc
      301 tgcgctactg catcaactcg gcgtcgatca agctggagaa ggacgcggag tgaagaccgc
      361 ggcttgcgcc gctccggcat gagccgccgc cctgcaggag cggtggaggc cgcgcaccac
      421 gcggacgaaa aaaacccgcg ccagcctctc ggctgcgcgg gtttttcgtg tgctggagaa
      481 agcgcttaca cgcgttccca caccgtggtg atgccctggc cgccgccgat gcacatggtg
      541 gcgacgccgt agcggccatt cacgcggatc agctcgtgca gcagcttggt gatgatcacc
      601 gagccggttg cgccgaccgg gtggccgagc gagatcgcgc cgccgttcgg gttgaccttg
      661 gcggtgtcga ggccgaggcc gcggttcacc gtgatcgact gcgccgcgaa ggcttcgttg
      721 gactcgatca cgtcgatctg gtccagcttc agcccggcac gctgcagcgc gagcttggtg
      781 gcggggatcg ggccctcgcc catcacctcg ttgggcacgc cggcgatggc gtaggacacc
      841 aggcgggcga tcggcttgtg gccggcggac gcggccttgg cggcatcggc cagcaccagg
      901 aaggcggcgg cgtcgttgat gcccgaggcg ttgccggcgg tgaccgaacc atccttcttg
      961 aacgccggct tcatcttgcc cagcgcttcc atggtggtca tgcgcggatg ctcgtcggtg
     1021 tcgaacacca cggtgccctt gcgggtctcg aaggtgatcg gaacgatctg gcccttgaag
     1081 cggccctcgg cgatcgccgc ggcggcgcgc ttctgcgact cgagcgcaaa ggcgtcctgc
     1141 tcttcacggg tgatgccgtg cttggtgcag aggttctcgg cggtgatgcc catgtggccc
     1201 acgccgaacg ggtcggtcag cacggcgacc atcgagtcga tggccttggt gtcgcccatg
     1261 cgcgcgccgc tgcgcagcgc gggcagcagg taggcgccgc gcgacatgac ctcgacgcca
     1321 ccgccgatgg cgaagtcggc atcgcccagc atgatggcct gggccgagct gacgatggcc
     1381 tgctgcgccg agccgcacag gcggctgacc tggaaggcga cggaatccat cgacatgccg
     1441 gcattgatcg tcgccacgcg cgacacgtag gcgtagcggg agtcggtcgg aatgcagtgg
     1501 ccgacggagg cgaacgagac cgccttcgga tccacacccg cgcgcgcgat cgcttccttg
     1561 atcaccacgg cgccgaggtc cgacggctcc atgtccttca gcgaaccacc gaagccaccc
     1621 acggcggaac gaacagcact cagaacgacg acttcacgat ttgccataac ccactccctt
     1681 gttgagatta gacgtgtcac cgccccgccc agcccgcgac cgcgagcagg aagagcagga
     1741 acagacacac gagcagagcc cgccagagca ggctcactgt gttttgcata tggtcgacgc
     1801 ccgcctcgct ccccaggccc atctcgggcc ggtccaagag ctcgccggct tcatgaaccg
     1861 gcatgccgag ccgcacgccc agcgcgccgc caccacttgc gatcagtata gccgacgacc
     1921 tctccggcca cagcaccgcc tgcgaacgcc agcagtagat cgcatcctcg aagttgccca
     1981 tgatggagaa cacgatcgcg gtgatccgca ccggcagcca ctcgatcgcc tcgcgcgcgc
     2041 cccgcgcgaa gcgcccgaag cccgcggcgc cagcatcgcg cccgccccac tcctcggcca
     2101 gcaagccggc gaggcggtac atcaccgccc cgctcgggcc gggcagcagc acgaaccaga
     2161 acatcacgcc gaacagcctg cggtgcgaga cgaccagcgc ctcctcgatg gccaggcggg
     2221 cgatctcgtt cgccgacgcg ccgtcatggc gcgtgccgcg ccagtcctcg agcaggctgc
     2281 gcgcgccctc cggctcgccc agtcgcaggg ccacgtggat cgccgaaaag aagcgcgtgt
     2341 cgtggcgaaa gccgatgcac aggtagagca cgaccacgtt gaagagaaag gccagcgccg
     2401 gatgcatctc ccacagcagc cagaagccga acgcactcgc gaacgccgcc gtcggcacca
     2461 ggagcagcca ggccacacgc ccctgggcgg ccgaggcagc atcgaaacgg gcgcgcaccc
     2521 cctcgaccac gccgcgcacc ccgcgcaccg tccagccgcg cgccggcagc ggacgcagct
     2581 gttcgagcac gagcgccagg atcagggaga agaaggtcat gcagccaaag catcgcgggc
     2641 gccagcggcc ccgcccatga agcgggttta tcggtgcggc aagatagcac aaaggcaagc
     2701 acgcgcagca ggcgcggcag cggccgacac gctcaggctt cgtcctgcag catacgatag
     2761 agcgacatca ggattcccgc cgtcgcgccc cagatgaaat acccgtgcca gggcatcgcg
     2821 tggaaacgcc gcatccgccc ctcgtgcagg atgctgtgct cctgatggtt gcgcggatcg
     2881 aggaagtgcg cgagcggcac ctcgaaggcc tcggcgacct cgaaggcgtc gagcgtcaat
     2941 tcgagcggcg gatgcaccac gccgaccacc ggcgtcacgc ggaaacccgt gccggtgaag
     3001 tagtcgggca gcgcaccgat caattcgacg tgacggcggg cgagcccgat ctcctcctcc
     3061 gtctcgcgca gcgcggcgtg cgccggcgag ggatcgcttt cctcgagccg gccgccggga
     3121 aagctgatct cccccgggtg gtggtgaagg tggtcggtgc gccgggtcag cagcaccgac
     3181 ggggcctcgc tgcgcaccac cagcggcacc agcaccgccg ctggcttggg cggacgcgag
     3241 cgcgcgaggt cgcgaccatc gccgttgaac tcgccctccc cgcgcgggcc ctcggcgagc
     3301 cgcaggcgaa tgcgctccag agcaggaaga ccatgccttg cacttccagg attcacgcca
     3361 tgcctcagta acgtttcttg agcagcaggc ggtcgccctc gcgccgccag tccatgcggc
     3421 cgagaaaact catgccgagc aggacgtagg gcagttcgga ctcatgcacc gccgcctcga
     3481 tgccatacag gcgcatcccc ttgagctcga ccgaatcgag cttcacccgc cacacccgcg
     3541 ccgtgccgtt ggcggtctcg ctctgcccgg gctggccgga acggtagtcg atcccgagcc
     3601 gcaccgcctc gttgcggccg agcgccacca gggtggcccc ggtatccacc agaacccgca
     3661 cgctcctgcc attgacgctc gcatcggcga agaagtgccc gcccccatcc gacaccaggc
     3721 tcgcctccgc gacgctcgca cccggcgcgc tggcggcgtg ctcgccgacg cgcagctgga
     3781 aagttcgccc gtcgtgctcg agcgtcgccg tctggccggc gagcgcacgc agccggacac
     3841 cttcgcgcgt ggcctcgttc acgcggatcg tttgcggcgc ggctccatcg acgaccagca
     3901 cggccttgtt tccaagcgcg ccggccatga cgacgtccag cgccagcgcg ggtgaggcga
     3961 ggcagacccc cccgagcagg agcgcgcagg atcgtttcaa ggcagtcctc gatccggggg
     4021 ctgggcgccc cggccgcaag ctcggccagg accgggggaa aacatcgttg cgggacatgc
     4081 cgtgcagctc ctcgctattg cccaggctgc tcggtgacca actcccgcca catgaacctg
     4141 cggaatgttc cgctcaacga cgcgggcggc accggcaggc tgatctggcg attgtccgaa
     4201 gtgttgatga tggccacttc cttgccctcc aggcggatga ccgccaaacc cacccccaag
     4261 gcctgggtca ggagctcgcc caccttcaag ccctccacgg tctcgacgct gcttccggtg
     4321 cggtaatcga agaaatacag gtaactccgg ccgccgaccg tgcacgcttc gcgctcgggg
     4381 acgttcgtca ccgccgtcaa cacgccgctg acgatcttga aatccacatt gatccgctcg
     4441 cccgcctcgg cgctcagatc gacgaaccat ccgggacccg tcgtccagtc gaccgactcc
     4501 tcggtgatcg tccgcgtcgc cccgctcgcc gtgatcacct gctggaccac acccgccgcg
     4561 gcgcggaaat tgccccagcc cgtatccgcg agcggctcgc gcactgcgta gatcgactgc
     4621 accgaggcat cgtccagatc gccctggccg agatacttgc cggtcccgac gaagacgacc
     4681 cgcttcagcg taccgtcgct cgccttgacc tccgccagct ccggccgggt cgtgatcggc
     4741 tgcgtgctgc cgaagctcgc gagcagcgtc gcggtctcgg cggtaagatc gaagcgccac
     4801 agcctgccgg agagatcgcc tgcgtaggca taacgcgtgg tgtcgtcgag gcggatgtta
     4861 tcgacccagt tgctgaccct cgcgatgccg ctcttcgacg ggtcggactc gttgtcggtc
     4921 acgatctcgg aaaccttgtc gccgctctcg gcatcgagga cgtacaagcg ccccttgccg
     4981 tcacccgtcg aggcgttgtt gtagcccgat gcgatcagga ccacccactt gccgccgtgc
     5041 ttggtgatga ccggattggc gaacgcaagg ccgagatccg aatcgtcggc attgccgaac
     5101 tcccacagga tcgacggatt ggtcgtgtcg gtgatgtcga gggcgaaata cgagcgcccg
     5161 cccttgccca gcccgaccac cgcgatggtg cgccagtcgc tcgctccggc gtcgtcgcag
     5221 tcgtccgcga cgcagatgtc cccgaccgcg atcgcgccat ccacgtagta ctggtgcggc
     5281 accccgctgg tcttgccgta gtccttgtgc gccagcttgt gcaggttcgg gatcaccgcc
     5341 gacggcacgt acgcccagcg ctccgtgccg gtgtcggcat cgaaggcatg cagcatcccg
     5401 tcgttcgccc cgaccagcac gatccctgcc cgagcgctct tggccgtgac gaagtcggcg
     5461 tagccggagt ccgaatactt gtacggcggt cgccgcacaa agaccgggtg cgaactgacg
     5521 atgtccccga gcacatgcag gcgatcgcgc agggtacggg tggcgttgcc cgcctggtct
     5581 tccttcgacg agtcgccgcg gatgaagtcg atcacgtcgt tggtcagtgc gtccggcagc
     5641 gaggaatgca ccgagcgcac attgctcgcg gtgaagtcga gacgcgtctt cccgcttccc
     5701 ttcatgtaga tcttgcggct gctccatccc gtcccggccg ccaactcatc cagcttcgcc
     5761 tgggccgacc acatccggtc gggctcggag gcgagcgtcc cgctgcggag attgatctct
     5821 cgcgcctgca ggtcgccatc ccagtgctgc gtgcggtagc tcgccacgta ggcgtagttg
     5881 tcgcccgcaa ccggctcgag gctgctcgtc gccgcgccag aacccgcccc cgtgcgcgcc
     5941 gccgcggtgt tcagcgcgcg caccaagccg ctgaccaccg cgtccggcgt cttcgcgctg
     6001 aagtaggctc cgcgcccgtt caccgccgcg tgccagaggt catcgacgcg ctcgatgaag
     6061 gtcgcggtct cgttcgtttc ggtcgtcctg gggtccggcc aattcttcga accgccgagg
     6121 atggcggagt agtcgagttc cagtccggtt tcgtagttct cggtgtactt gagcaggccg
     6181 tcgatgccga agccaagcgt gaaggtggtc atgtgctggg tcgaggcctt ctcgtcgcgg
     6241 cccccaccct gcacgtcgtt gaagcacaca tcctcaccct cgatcctgcc cgtgcagttg
     6301 ccaagcgagg catcgcgcag atcggtctcg tagtagtaca tcgcgatgtc ggccagggag
     6361 ttcttgacct tatacgcatc cagcatcggc cgtggcgcat cgccatcgcg gtcccccacg
     6421 ccgcccgagt tcgcgatgtt gaacggcaca ttcttgtcct ggttccacga accgtccgtc
     6481 gccatgatca cgaagttctg ctggcaggaa tactgcacgg ggtcgtcact tgcgctgagc
     6541 cgactgctgc cgtcgaaacc cgcatacatg cggccgatct tggcgaggga acctcgcaag
     6601 ggcgtccacg cgtccgccgg agtcttgtac agcatcctga agaattcact gcgctggttg
     6661 tcgggcgagc atttgtcgct acctgcggcg cagaagtccc ccagcggctg gaagcggccc
     6721 cggtcatccg ccgtcacccc ggtttcgctc accgtcgaga agccgatgcg aagcccgtcc
     6781 ggattgagca gctggccgaa tgccctgccc gacgcactct tcatcgcgtt gatgcgcgaa
     6841 cggtagtacg aataccagtt ggcgaagttc tgtttgtcga agcccgttgc ggagctggtc
     6901 accttctcga atacgtcgct cgtgccgatg cccaggttgc aatacttgta gatgcccgct
     6961 cccgtatcca ggctcccatt cgccttgtaa acatattcca ggggaagcgg tcccttgttc
     7021 ggccgcttgt acttgtagta ataggccgcc tccttcggat cgcagcgacc gccgtccgca
     7081 ctgccgcaat cccaatcggc tgcgcggaaa tccttgctca gatcgacgac cgccgaggcg
     7141 ccgtcgaagc cgtccttcct ggcggcggta aacgacgccg ccgggtatga ggtcccgtcg
     7201 gccttgacag gggggacgta cttgaccgca gggtcgtaat acatgccatt gcaggctggg
     7261 ctggcgaatc catagggccg gacgacctcg aaacccttct tcgaccgcac ccaatacggc
     7321 ggatacgatg ccgcatccgg aaggtaggtc cactccatcg agcccgagtc gtcgagcacg
     7381 aacatgatgt tgggcttgac ctggatggca ccgccggtcg gaatcggcgt gtccgcgatt
     7441 tccacctctg ccccattcgc cgcggtcgcc acgcaaaggc cgaggaacag acgtttgagc
     7501 aggcggacgc gagaaacgcg cggattcgcg caagcggatc gcccggagtc ggagttcaag
     7561 cgtttgaacg acatttccca cacctctcaa ttggccagca cgacctgcac gtggctgacc
     7621 gcgttgttcg gtcctgccac acgcgtcgtc acccgataca acaactggga cgactgcgca
     7681 ttggtcgcgt gatacccgac attggtcatc gaacgcccgt cctcagccgc cgcgctggta
     7741 cgcgtgtaca tttcacacgc cacggtgacg ccccctggac tggtgccatt cggcggcccg
     7801 tcggcattgc acatccggtt gatgacatag gtcgcggtgt aacccggcgg caggagattg
     7861 tccgcgacgg cggccgcgac catgttgcag tcgggattgt cagggtcccc cgcctcccag
     7921 cgcacgttgt cggcggtcga ggcggtcaag cctccggtca ggtcgcagcc cgagcgggag
     7981 gtggcgtagt accccgaggc cttgctggtc tgcaggacaa tcccgccatt ggcggcgatc
     8041 tgcccctgga tccaggccag tgccgcctcg gtcccggcgt cgccagcctg ggtcgccgcc
     8101 tggcggaagg ccaggttgcc tgcgatcgtg gtgccggtgt cgatcgagcg caccaaggcc
     8161 accgatgcga gcgacagcac cacgagcgcg atcaggacgg tgaacagcac gatcccgcgc
     8221 tgcacccggg gctggtttcg gtcatgcagg ttcatgctct cctcctcatg gcgcccagac
     8281 cacgttgcgc agcgggatca cggtctcgaa gacgcgatga cggtagttgg ggttcgcggc
     8341 gatcaggtcc gtcgtcgcct cccccatcca cgcgggagcc tgcgcagcgg gcaccgccgt
     8401 cttttcgaat tgcgggtgac gcgtgaccac gccgacgcgg atggcgcgga tctgcgcggt
     8461 ctcgtcggcg tcgagcgcgg cccagtcgcc ggtcgcgctc cgccacgtca gcgcgccacc
     8521 atcgacgacg ccatactccg cctgcaggtc gacgacctgg gcgaccatcg gcgtgctgtt
     8581 ggcacaggtc acggcggcgt cggcgacatc gaccggatcg ctctcgacca ggtgatcgca
     8641 acgcacggag aagcggcgtc cgaaggaagt accgtcgccg tagcggaacg caatgtctcc
     8701 aaccacatac gcaacgggaa aagggtcctt agggttgtag ggagagccgt tcccggagtt
     8761 gtgaaccaag ttcactccgt tgccggtgtt cttcggcggc tgcgaaagtt gcatcaccgt
     8821 acagaccttg ttgccacctc gatcgcccag cacaacgaga tcaccttctt gcagtccccc
     8881 gtcactgccc accgtgacaa tcgaagaagg gttgggcatg ttcttgacga tcgacaaagg
     8941 cagcgcatcg gccgccccgt cactacgcat caggacgatc gaatccgctc cgtcgccgcc
     9001 atcgatgatg cgcgcaggca cgagcgacaa cgcgttcatc accacctcgc cggccgcacc
     9061 gttgttcttg tagatgttga ttccgttcct gcagtacgcc ccctcgggcc cgaagagccc
     9121 gtagcccgcc atgcggatct cctgctcgag cagatacacc gccaacgccc cgttggtctg
     9181 ggaatcgttg ccgcccgtgc tggtacgctt ctgcccctcg aaagcctgca tgacctgcga
     9241 ggccaccagc agcaccacca gcccggtggc caggcccacc agcagttcca cgagggtcag
     9301 gccgcgctgt gccgaattcc gtcccatgtc ctctactcct acttcgcgac atgcgcgacg
     9361 acgacgacgt tgctcacgcg gtccgcgccc ggcgcctgcc aggtgaccgt caccgtgacg
     9421 cgctcgcccg cgatcgtcgt ggtgcgcttg ccattgggca gcgatgcgcc cggaaaggcc
     9481 gcgctgacat cggtatccgc ctcgccgaaa gtacccggcg cgttcggtcc cgcccagatc
     9541 tcgccgatgc gggcattcgc gatgaagctc gcgtcggtgc ggtatttcgc cgaggtggtg
     9601 tgctggatcg cggcggcctg caggccgatg atgccgagca caccgaaggc cagcacgagc
     9661 accgagatga gcacctcgag caggatgatc cccctggcgc cgcgaggacg gcgagaagca
     9721 cgcataccca tgatcagcac ttcctcggat cggtggaacc gctcacgttg gggtcgcaca
     9781 tgcgcacccc gccggtgccg atggtgatcc tcaggtcgcg cgactgcgcg gccggcaagg
     9841 cagaggtcgg cacgtcgatg tcgatctggg tcagcgtgtt gtcggccctg cccagcccgt
     9901 cgaaaaccac ggtggtcgca tcgtccggta cggcgctcac caccacgccg ccggcgccct
     9961 cgctgcccga gcgcgcctgg atggtcgccc cgccgcccgc aaaccgcacc acccagccgc
    10021 cgcccgtacc gacgagggcg aactcgaccc gagcgttgcg ccgcaccgcc tccgcgcgcg
    10081 cgacctgcaa cccattctgg atcgactccg ccgcggtgcg aatgcggccg ttctggatcc
    10141 actcgttgaa ggaagggacc gccagcgtca tcaacaggct cagcacggcc accgtgacca
    10201 tcagctcgac gagggagaac ccgcgctcga gagcgcatcg tcgcgcgttg acaagaaagg
    10261 acttcgattt catcgccagc accccatccg caggccttgc gacccgcatc cacggcctca
    10321 ctcagcagcc accgttcttg gagaccaccc agcagttgcc gctgtcgccc caggaggtgg
    10381 tcgaagtcat cgtgttcgac tcgttgatcg tgtagacgaa accgctcatc gcgccggtcc
    10441 cggtcgcggt gagggtgtag gtcgtggcgc tctccgacgg gcagccgctg aaggtgaagt
    10501 actgcgtatt ggccggacag ggcggtgaag aatcaccacc accttcggtt ggcaccgctt
    10561 tataggtccg gttgtcctgg aaccactgct cgagcagcac ccgcccgttc gccagcccgg
    10621 aggtggcctg cgggatgcgg cccttgacga ggtagtcgtt gtaggcgggc agcgcgatcg
    10681 aggcgaggat gccgaggatg gcgacggtga ccatcagctc gatcagggtg aagcctgctt
    10741 gtgcggtagt tttcatgatg cgtgcgcttc ttcggtgcag aggatcgacg gaatgtccat
    10801 gaacagccta acccgaccac gtgcgcgacc ccagccttgc acgacgagcg gcgcgagcga
    10861 caggacctgc ggcagcgcgg caccgaatgg cgtcgatcga atccgcacag ccaggggaac
    10921 ggaaggattc tgtcggaaaa atttacagcc tgttccaagc acagtcggca ggagcttgtt
    10981 tttgcgagtt tttcttagaa ggcacagtac ttgcttatga gcaccacact cgcaccacca
    11041 cccgaatatt gcgactggaa caggaaaacc atgaaaacca agaccctgat cggcgctctg
    11101 gccgccacca gcctgagctt cagcgcgcac gcgacgctga tcgacttcga ctcgctcacc
    11161 agtggccagg aattcaccac ctacagcggc ctgacgtgga cgaacatggt ggccctcgac
    11221 ccctcatcga gccccgagtt cgcagacacg ggatacgtgt ccggcgtcca gtcgccgaag
    11281 aacatcgcct tgaacttcgc gggctcgcct gcttccgtca catcgaacga tggcttccgg
    11341 ctcaacagcg ggtatttcac ctctgcgtat tacaacggcc tgaccctcga tttcatcggc
    11401 accgcaggtg gaaccaagct gtccaagacc gtgatgctca gcctgcagcc gctgttcgtt
    11461 gaattcgacg atcggtggaa catcgacacg ctccaaatgg ccactacctg cgataccacc
    11521 gcggactgca agccgatcag cgaaaacgtc gcgggcaaat tcaacttcgc cctcgatgat
    11581 ctccgcatcg acgaatccac cagcacggtg cccgagcccg gcatgctggc gctgctgggc
    11641 ggcggcctgc tcggcatgac gctgatccgc cgtcgccgcg gagcttcggc ttcctgactc
    11701 aagcccaggt gtcgacgacg ccgcccgcgg tgctccctac cgcaggcggg cgcggaatcg
    11761 cctgaagcaa ctgcatcgcg ctctggccct ggaggtcgag cgccttgcgc agcacttcca
    11821 ccgaggcctc ctgctgcacc tgcgcgagcg cgttgttcga tgccatcgcg gcgattgcgg
    11881 atgcgtccat gtcgattctc ctgacggcca ccccgagcgg gccgatgacg atggaggaca
    11941 taacggcagc gagcgcaagg gcttgagccc ttcctcctgc cggacgtgtc cgaaaacacg
    12001 acgggcgcct cgcggcgccc gtcggctttc cggcccagcc ttcccgctca gtcgcggaag
    12061 ttgccgtact gcagcgggaa gtcggtgatc tgcttcttga ccagcgcgat cgcctcctgc
    12121 agcacgtcgc gcttggcgcc ggacacacgc acggcgtcgc cctggatcgc ggcctgcacc
    12181 ttcatcttgc tgtccttcaa cagcttgacg atcttcttgg ccagttcctg ctccacgccg
    12241 acgcgtacct tgacctcctg cttgaccttg ttgccggaga tcttctgcac gtcgccatag
    12301 tccaggcagc gcacatccac gttcttcttg gtcatctcgg gcagcaggat ggtcttgatc
    12361 tgctcgagct ggaagtcgct gtcgccgtag agcgtcagca gcttttcggc gagctcgatc
    12421 ttcgcgctcg tgcccttgaa gtcgtggcgg ccgtcgacct tgcggttggc ctgctcgacc
    12481 gcgttgcgca gcgcgggctg gtcgacctcg gacaggatgt cgaaagacgg catggctccc
    12541 ctcccccgct cagccgaagt ggcagatgta gtggtagggc tcgccggcaa cctcgatgtc
    12601 gaagctggag ttgcccggca cgtcgaagga ctcgccggcg ccgtaggtct tccattcggc
    12661 ggcccccttc aggcgcacgc ggcaggagcc ggccacgcct tccatgatct cgggcgcgcc
    12721 ggtgttgaag gtgagcgagg ccggcaggat gacgccgacc gacttcttcg tgccgtccgc
    12781 gaactgcacg ctgtggctga cgcacttgcc gtcgaagtag acgttggcct gggtggtgac
    12841 ggcgacgccg tcgagcttgg cggtgatgcc catcgcttgg attttcctta ttcgatgccg
    12901 agcagcttct ggatgatgcc cttggcgatg aagccgacga agcccacgcc caggccgagg
    12961 aacagccaca tcatgccgta gcggccggcc ttggattcct tgcccaggtt ccagatgatg
    13021 aagaccatga acaggatcag gccggtgagg ccgagcttga gggcgagatc ctcgaactcg
    13081 gcgaacgtga gtccgaggat gaaggcttcg ttgtccatcg ccaggggtcc gttgcgggct
    13141 tagccgcgct tggccttggc gttggccgcg atgcgcatgc gcagcgcgtt gaggcggatg
    13201 aagccgtgcg cgtccttctg gttgtaggcg ccggcgtcgt cctcgaaggt ggcgatcgtc
    13261 ggatcgaaca gcgagtcggt cttggagtcg cggccggtga cgatgacgtt gcccttgtag
    13321 agcttgaggc gcacccagcc gttgacggtc tgctgggtgt ggtcgatgag cgcctggatg
    13381 gcacggcgct cggggctcca ccagtagccg ttgtagatca tgctggcgta gcgcggcatg
    13441 aggtcgtcct tgagatgggc gacttcgcgg tcgagcgtaa tcgactcgat ggcgcggtgc
    13501 gcacgcagca ggacggtgcc gcccggggtc tcgtagcagc cgcggctctt catgccgacg
    13561 tagcggttct ccaccaggtc gaggcggccg atgccgtgct tgccgccgag ttcgttgagc
    13621 ctggcgagca gctcgtgcgg cttcatgcgc ttgccgtcga tggcgaccag gtcgccgtgc
    13681 tcgaattcga ggtcgatgta ctcggcggcg tcgggcgcag cctcgggcga caccgtccag
    13741 cgccacatcg actcctcggc ctcggcggcg gggttctcga ggtggcggcc ctcgaaggag
    13801 atgtgcagca ggttggcgtc catcgagtag ggcgagccgc cctgcttgtg cttcatctcg
    13861 atggggatgc cgtgcttctc ggcgtaggcg agcagcttct cccgcgacag caggtcccac
    13921 tcgcgccacg gcgcgatgac cttcacgccc ggcatcagcg cgtagtagcc gagctcgaag
    13981 cggacctggt cgttgccctt gccggtggcg ccgtgcgaca ccgcgtcggc gccggtggcg
    14041 cgcgcgatct cgatctggcg cttggcgatc agcggacgcg cgatcgaggt gccgagcagg
    14101 tactcgcctt cgtagatcgt gttggcgcgg aacatcggga agacgaagtc gcgcacgaac
    14161 tcttcgcgca ggtcgtcgat gaagatgttc tcgggcttga tgccgaactt cagcgccttg
    14221 gtgcgcgccg gctcgagttc ctcgccctgg ccgaggtcgg cggtgaaggt gaccacctcg
    14281 cactggtagg tgtcctgcag ccacttcagg atgaccgaag tgtccagacc gcccgagtag
    14341 gcgagcacta ctttgttgac gtcgctcatg ctgttttcct gtttcctgcg gtgttgccgg
    14401 cgcgcacgcc cgtgcgtgcc gtgattgttc gtcggctcag ctctcgatgc ggccaagcat
    14461 caggtattcc atcagcgcct tctgcgcgtg caggcggttc tcggcctcgt cccacaccac
    14521 cgactgcggg ccgtcgatga cctcggcggt gacctcctcg ccgcggtgcg cgggcaggca
    14581 gtgcatgaag acggcgtcct ggtgcgcgac cgacatcatg tcggcgtcca cgcaccagtc
    14641 ggcgaaggcc ttcatgcgcg cctcgttctc ggcctcgaag cccatcgagg tccacacgtc
    14701 ggtggtcacc aggtcggcgc ccttgcaggc ttccatcggg tcggcgaact gctcgaagtg
    14761 gttggtgccg aacaggccgg cgcgctcggg ttcgacctcg tagcccggcg gggtcgacac
    14821 atgcacgttg aagtccagca cctcggcggc ctgcagccag gtgttgcaca tgttgttgct
    14881 gtcgccgatc cacgccaccg tcttgccccg gatcgagccg cggtgctcga tgaaggtgag
    14941 gatgtcggcg aggatctgac aggggtggta ttcgttggtg aggccattga tgaccggcac
    15001 gcgcgagttg gcggcgaagc gctcgacgat gtcctgctcg aaggtgcgga tcatcaccag
    15061 gtcgctcatg cgcgagatga cctggccggc gtcctccacc ggctcaccgc ggccgagctg
    15121 cgagtcgcgg gtgttgagat agatcgccga gccgccgagc tggtgcatgc cggcctcgaa
    15181 ggacaggcgc gtgcgcgtgc tggccttctc gaagatcatc accagcgtgc ggtcgaagag
    15241 cgggtggtag ggctcgtagc gcttgaactt gtccttgatc cacttcgcgc gcgcgaacac
    15301 gtagtcgtat tcctcgcggg tgaaatcctt gaactgcagg tagtgcctga tgggagaact
    15361 catacgcggt ccttagccgt tcgcgaggaa gtcgcggatc atcggcgcca gcatggacac
    15421 cagggtctgc gcgtcggccg tggtgaaggt gagcgcgggc agcagtcgca ccacgcgctc
    15481 ggaggtgacc gacagcagca ggccgtgctc cgcggcgcgc gccatcagca cgccgcaggg
    15541 gcggtcgagc tcgatgccga tcatgagccc gcggccgcgg atgtcgacca cgccagcctc
    15601 gccggcgagc gcctcggcca tgcccttgcg gatcgcctcg ccgacggcga cggcgttgtc
    15661 catgagcttg tcctcgacga tggcgtcgaa ggtggccagg cccgccgcgc aggcgagcgg
    15721 attgccgccg aaggtggagc cgtggttgcc cggcccgaac aggcccttgg cgaggccgct
    15781 ggtgacgcag gcaccgatcg gcacgcccga ggccaggccc ttggccagcg tcatcacgtc
    15841 gggtctggtg ccggcatgct gccagccgaa ccacttgccg gtgcggccca tgccgcactg
    15901 gacctcgtcg cagatcatga gccagccctt ctcgtcgcac agggcgcgca gctcacgctg
    15961 gaaggcctcg tcggcgacgt tgacgccgcc ctcgccctgg atcatctcga gcatcaccgc
    16021 ggcaacgctg tggttgtgct cgccgacctt gcggatggcc tcgatgtcct tgtacggcac
    16081 gcggatgaag ccctgcacca gcggctcgaa gccggcctgc gccttgcggt tgccggtggc
    16141 cgacagcgtg gccatggtgc ggccgtggaa ggcgctttcc atgacgatga tgtgcggcag
    16201 ctcgatgccc ttgttgtggc cgtacatgcg tgcgagcttg atcgccgcct cgttggcctc
    16261 gcagcccgag ttgcagaaga acacctcgtc catgcccgcg gcctcggcga tgcggtcgga
    16321 gagttgctcc tgcagcggga tgcggtacag attggacgtg tgcaggacgc gctcggcctg
    16381 gtcggcgatg gccttgacca ggcgggggtg cttgtacccg agcgtgttca ccgcgatgcc
    16441 ggagagggca tcgagataac gcttgcccgt ctcgtcgtac agccacacgc cctcgccgtg
    16501 cgtgaaggcc acaggcaggc gggcgtaggt attcatgaca tgggacatgg gcttacctcg
    16561 atctgtgcga agccgaaaaa cgcacacggc ggcagacgcc gccgtgcagg aaatgtgccg
    16621 atgttaagcc aaaacggccg gacctgtaca taagcggcag gctgcgcagg gcctgccgca
    16681 ccctcgtgca gcaccactcg gacggctgcc tcgggcgggt ggaccggcag ccctgccaga
    16741 gcgatgcagg ccggattggc cgcgggggat ttctgctaga atcgcggccg tcctgattcc
    16801 ggcgacgaag aaccggaaca tgcgcatccc cgaagccgcc aaggcatcac acatgaatca
    16861 gaagatcgag aacttcatca tcgtcggggt cacgagggag gggaagaaat tccgtccgag
    16921 cgactggtcc gaccgcctgt gcggtgtcat gtccgccttt ggcgccgatc accgcatgac
    16981 gtattcgccc tacgtgcgcc ccggctgcac gctcaagggc gacaagaccg tccttgtcga
    17041 cgcccgcctc tacgacgtcg agccgctggc ctacaagttc atggtgaact tcgccaacga
    17101 caacaacctc cagatcgagt gggtgggcga cgcgccgctc tgagacggca tcgcctgcgg
    17161 gagcacccgt tcgcggctgc cgccgtccct gcatgaaccg cagcacctgc gtgaatggcc
    17221 gctcccgcat cgaccgtgac gcctgcgcaa actccgttcg cggctgccgc cgctcctaca
    17281 tcgacccttg cggctgcggc ccccttccat cccgggcacg cccctgtagg agcgccggca
    17341 ggcgcgaaca ggcgaacagg actcccgccg ccctcatgcg cacgacgccc aacaaaaaag
    17401 cgacccgcag gtcgctttct cgatctcggc gccggagcgc cggcatgcgg caagaatcag
    17461 gcagccatcg acttgacggc ggccgacagg cggctcttgt ggcgagcagc cttgttcttg
    17521 tggatgatct tcttgtcggc gatgctgtcg atggtgctca tcgaggtgcg aaagaccgac
    17581 tgagccgccg ccttgtcgcc acccacgatg gccttgcgca cggccttgat cgcggtacgc
    17641 aggcgggaac gaaggctggc gttgtgggcg cgggccttgg tcgcctgacg ggcgcgcttg
    17701 cgagcttgtg ccgagttggc catagatttg aagtccgtat tggtggttct ggaaaagtcc
    17761 gcgattatat ggacccgcca cggtgaatgc aagcgtgttt tccgtctttc cgcttatcgg
    17821 gacagcggcg gacggctatg atgcgcgctc cgcattttcc gtgcgccgcc ggccggcgca
    17881 tgcacccacc gaatgaacct cctgcgcgcg ctcgccaccg tcagcggcat gaccctgctg
    17941 tcccgcatcc tgggcttcgt ccgcgacctc gtgatcgcgc gcgccttcgg cgccggcatg
    18001 gcgaccgacg ccttcttcgt cgccttccgc ctgcccaacc tgctgcgccg catgttcgcc
    18061 gagggcgcct tctcgcaggc cttcgtgccc atcctcgccg agtacaagaa ccgccagggc
    18121 gaggccgcca cccacaccct ggtcagccgc gtcgccaccg tgctggggct ggtggtggcg
    18181 gtggtcgcgg cgctcggcgc gctcgccgcg ccgctgatca tctacgtgtc ggcgccgggc
    18241 ttctccggag atccgggcaa gttcgagctc accgtcgagc tcacccgcat caccttcccc
    18301 tacatcttct tcatgtcgct ggtggcactc gccggcggcg tgctcaacac ctggagccgc
    18361 ttcgccatcc cggccttcac gccggtgctg ctcaacatcg ccttcatcgg catggcgctg
    18421 ttcgcggtgc cctggttcga cccgccggtg ctggcgctgg cctgggcggt gttcctcggc
    18481 ggcctgctgc agctcgcgct gcaggtccgc ccgctgatga agatcggcat gatgccgcgc
    18541 ttcgacctcg acctcgccga ccccggcgtg cgccgcgtca tgaagctgat ggcgccggcg
    18601 atcctgggcg tgtcggtgag ccagatctca ctgctgatca acaccatctt cgcctccttc
    18661 ctcgagagcg gcagcgtgtc ctggctgtat tacgccgacc gcctgatgga attccctgcc
    18721 ggcctgctcg gcgtggcgct gggcaccatc ctgctgccca gcctctccaa gctgcacgcc
    18781 gacgacaagg ccgaggagtt ctcctcgctg ctcgactggg gcctgcgcct gaccctgatg
    18841 ctgaccctgc ccgccgcgct cggcctcgcg ctgctggcgg tgccgctggc ggcgaccttg
    18901 ttcaactacg gcgcgttctc tgcgagcgac gtgatgcaga cacgcagcgc cttggtcgcc
    18961 tacagcgtgg gcctgaccgg gctgatcctg gtgaaggtgc tggcaccggg tttctacgcg
    19021 cgccaggaca tccgcacgcc ggtgaagatc gccatcctga ccctggccgc gacgcagctg
    19081 atgaacctcg cgttcatcgt tccgctccgt cacgccggcc tggcgctggc gatcggcctg
    19141 gcgtcctgcc tcaacgccgc cctgctgtat cgggggctgc gcaagcgcga ggtgtacatc
    19201 ccccagccgg gctggggctc gttcgcgctc aagttgctgg tcgcgctcgg cgtgatgggc
    19261 gcgacgctgt ggttcgcgag cgggccggcg agcctgtgga cccagatcgg cgggctggag
    19321 cgcggtctgc gcctggcgtt gatcgtgctg ggcggcgtgc tcgcctactt cgcgaccctg
    19381 ttcgccctgg gcttccgccc gcgcgacttc cgccgccgcg gcgcggcctg aggcgcacat
    19441 tcgcggctgc cgccgctcct acaacatccg gaactgcggc ggttctcctg cgcg
//
LOCUS       DAOTIN010000057        18213 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_3685_length_18213_cov_9.016632, whole genome shotgun sequence.
ACCESSION   DAOTIN010000057 DAOTIN010000000
VERSION     DAOTIN010000057.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 18213)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 18213)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18213
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3685_length_18213_cov_9.016632"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..619
                     /locus_tag="P5537_09960"
     CDS             <1..619
                     /locus_tag="P5537_09960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type IV pili methyl-accepting chemotaxis
                     transducer N-terminal domain-containing protein"
                     /protein_id="HRV78407.1"
                     /translation="PVEMQLRLRQGIAEFERSLAVLQAASLAPELGEALEDVGRVWAD
                     FRDALGAAARPPAGAARVLQLSEDFITAADFLNAVAGGFAASGSLYMVNVAGRNRMLS
                     QRVAKLFLFEGFEGCPDPQAQIAASCRAFEHNLQRLRENSGDLPELEAQIDATASLWS
                     RFVAALDPAIRQPHRIGRVRSVLDEGERLLRYTNTLVKLFERLAR"
     gene            768..992
                     /locus_tag="P5537_09965"
                     /pseudo
     CDS             768..992
                     /locus_tag="P5537_09965"
                     /inference="COORDINATES: protein motif:HMM:NF015048.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hotdog domain-containing protein"
     gene            1170..1508
                     /locus_tag="P5537_09970"
     CDS             1170..1508
                     /locus_tag="P5537_09970"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047617 - acyl-CoA hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HRV78408.1"
                     /translation="MPADLNPSGDVFGGWIMSMVDIAGAVPAIRVARSKVATVAVDSF
                     VFKQPVSTGDIVSFHAEVVRVGRTSITVDVEVYAERHPESPVVVKVTEARLTYVAVDE
                     FRAKRTIGAG"
     gene            complement(1534..2526)
                     /locus_tag="P5537_09975"
     CDS             complement(1534..2526)
                     /locus_tag="P5537_09975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLAC1 anion channel family protein"
                     /protein_id="HRV78409.1"
                     /translation="MNASAHPATVPATLRICRTEHFPVALFAIVMGLTGLALAWLKLH
                     HLGGAPAFIGNVLRLLASALFVFLAAMYLAKLVRHPQAVRADWMHPVKLNFFPAISIG
                     LILLAVAWARELPGFAAWIWGLGAALHLAFTLAAMSSWIHHPRYKLEHANPAWFIPVV
                     GNILVPIAGTGFAPADLSWFFFSIGVVFWLVLMTIVLHRLFFNEPLPERLTPTLFILI
                     APPAAGFLAWVALVDQIDAFARVLYFTALFLTLLLASNALRFLRLPFAIPAWAYSFPL
                     AAMTLAALEMGARTGSGFHHGLGLILLALLTMVVVLLALKTLGAARKGRICVPE"
     gene            2952..3443
                     /locus_tag="P5537_09980"
     CDS             2952..3443
                     /locus_tag="P5537_09980"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78410.1"
                     /translation="MKIEPMKNRRGAGPDIEGAGAGSPRKGAFGRSVQAFARMLPILI
                     GTLLLSSLLVAWLPRTPVLGWFGRSEWLDVLLGASFGSIAMGHPVAGYLLGGELLAGG
                     IGLMAVSALVVAWVTVGVVHLPAEALALGRAFALRRNLLCFASAIAVAWLTVASLRLV
                     GLA"
     gene            3440..3952
                     /locus_tag="P5537_09985"
     CDS             3440..3952
                     /locus_tag="P5537_09985"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78411.1"
                     /translation="MKKAARIPASWLYVAFGLAAHGVGLLLDPAVAQVALASFIDMTR
                     TILPVLGLVFVLMYLAERFLTPARTRSWLGRDSGTKGWLLALAAGMLSTGPAYAWYGL
                     LADLRTRGMRSALLAVLLYARAIKLPLLPLLAHYFGFAYMLVLSLFIALFALLNGWAM
                     ERLFPEPENE"
     gene            3949..4191
                     /locus_tag="P5537_09990"
     CDS             3949..4191
                     /locus_tag="P5537_09990"
                     /inference="COORDINATES: protein motif:HMM:NF015956.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046914 - transition metal ion binding
                     [Evidence IEA];
                     GO_process: GO:0006811 - monoatomic ion transport
                     [Evidence IEA];
                     GO_process: GO:0055072 - iron ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FeoA family protein"
                     /protein_id="HRV78412.1"
                     /translation="MKPALSTLDHLSVGATAVVRELDGGNEFSGRLAAMGLVLGAALQ
                     VMQNSGKGPMLVRVRDTRLALGRGEAQRILVERVPP"
     gene            4188..6197
                     /gene="feoB"
                     /locus_tag="P5537_09995"
     CDS             4188..6197
                     /gene="feoB"
                     /locus_tag="P5537_09995"
                     /inference="COORDINATES: protein motif:HMM:TIGR00437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HRV78413.1"
                     /translation="MNSPVRPILLGLAGQPNVGKTTVFNLLTGLDQHVGNWAGKTVER
                     AEGRLRHGDVEATLVDLPGTYSLSANSAEERVARDFLIFEKPDAVIVIVDASALERSL
                     YLLAELLALGLDTPVVLGLNMTDVAAAQGITIDPAVFSAALGLPVVALVARRAQGVAE
                     LTEAALRLARDPACFAPLRPEIAEPHREVLEDLHALLAAHVPAPYPARWVALKLLEGD
                     AELIALARRWAPEPVWERAAALLGEHEDAILDIAAGRYAWIERMARAAVSRPRLGQVS
                     FTDRLDRVALHPVWGLVMLLGVFALIFGLTFELAGPVQDWLESGVIEPFGAWLAERLA
                     GAPPWLVGLLVDGVLGGAGVVITFVPLLAVFFAALALLEDTGYFARAAYVMDRYMHRL
                     GLHGKSFLPLCLGFGCNVPAVMGARVIDSPSGRLLTILLAPLVPCSARLLVLAFLSPV
                     FFGAAALPVALVFIALNLALVAILGSLLDRSLFRGKKVFFIMEMPLYHVPSLRTIGRH
                     VRGHVLAFLRNAGSLILVFSVLLWALAWFPGEGLEHSWLAGFGRALAPLGELLGLDWR
                     LIVALLASFVAKENAIAALGILYGIEAEGEVLAQTLAASVPLASALSFLTATMLFVPC
                     VATLAVMRTETGSWRWPLFSVLLHLALSLLAAAVVHRGWIALAGG"
     gene            complement(6225..6662)
                     /gene="trxC"
                     /locus_tag="P5537_10000"
     CDS             complement(6225..6662)
                     /gene="trxC"
                     /locus_tag="P5537_10000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA];
                     GO_process: GO:0006662 - glycerol ether metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxC"
                     /protein_id="HRV78414.1"
                     /translation="MSDALHLVCPHCDAVNRVPAARLAEAPNCGKCGKPLFTAHPVEL
                     DAANFDRHVGRSDIPVLVDFWAPWCGPCRTMAPAFAQAAGMLEPQVRLAKLDTEANQA
                     LAARFGIRSIPTLALFRGGREVARQAGAMGAADIVRWVRGHAG"
     gene            6845..7432
                     /locus_tag="P5537_10005"
     CDS             6845..7432
                     /locus_tag="P5537_10005"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HRV78415.1"
                     /translation="MKQPRIVVMAGSRRREALSRRVAHACAQALRDAGAEVELVDLDD
                     YPAPLYDGDLEAASGLPEGIVRLQRVLHASDGLLVVNPEYNGSLTPLLKNTLDWCSRP
                     NPADPERSGGKVYAGRAAAVVGSSPGALGGMRVLFHVRDVLGYLGMQVIPQQLAVGKA
                     GEAVGADGRLDDAAQQGMLEGLAAALVDTARRMRS"
     gene            complement(7524..7970)
                     /locus_tag="P5537_10010"
     CDS             complement(7524..7970)
                     /locus_tag="P5537_10010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative zinc-binding protein"
                     /protein_id="HRV78416.1"
                     /translation="MAGRKKNLPLVYSCSGCSSAAQMANHVALRLDREGEAEMSCIAG
                     VGGNVPNLVNIARSGRPILALDGCALECTRSSLAERGVQPSVHLLLNEQGVKKRYATD
                     FDPEEAERVFAQARAAVRGLRGQAAAGKADGTADGKADEKADGKAD"
     gene            8222..9397
                     /locus_tag="P5537_10015"
     CDS             8222..9397
                     /locus_tag="P5537_10015"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy acid oxidase"
                     /protein_id="HRV78417.1"
                     /translation="MNPRRQHYRGRNPARAHNIAELRTMAARRLPNFCLEYLEGGGDD
                     ELALARNRRALDDILLLPRTLVDVSRCELAVALFGTDIAMPAVIAPTGFNGLLTHEGD
                     RVLAEAARAAGIPFCQSMVSTVALEDIAATGVRHWMQIYPFKDRDNLAAVVKRAEHAG
                     CEAIVLTTDASVFGNREWDRRNYRAPMKLTWRNVLDVGLHPRWIFDVLVPRGMPRFRN
                     LGDFLPPGMDSARNAAAFLAAQMDTSLTWDDVRRLRELWPRRLLVKGVLLPEDALRAK
                     EAGADGVVVTNHGGRQLDAAPAPIETLAAVRQAVGAEMTVIVDSGFRRGSDFVKARAL
                     GADAAMSGRATLYGLAAAGAPGAARALEIVRSEMERTLGLIGCARMAEVDARFVGRG"
     gene            complement(9431..9778)
                     /locus_tag="P5537_10020"
     CDS             complement(9431..9778)
                     /locus_tag="P5537_10020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1840 domain-containing protein"
                     /protein_id="HRV78418.1"
                     /translation="MLVTFKSHASADVIMFGDAAKKLIGILGKDPADAKGILTVQQLP
                     EAIARLKAAIEEERARQAELERQRGHADEEAEKEAGNTGMAAPVGLAQRAWPLLAMLE
                     ESLREETPVVWGV"
     gene            complement(9796..10353)
                     /locus_tag="P5537_10025"
     CDS             complement(9796..10353)
                     /locus_tag="P5537_10025"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine-guanine phosphoribosyltransferase"
                     /protein_id="HRV78419.1"
                     /translation="MSLNLEEIKRAREEADCLADAATVEAALDRMAAEITARLADANP
                     LVYAVMNGGLILAGRILPRLPFPLELAYLHATRYGHAIQGTLLDWRVRPTQDLRGRTV
                     LVLDDILDEGHTLEAIIAHLKEEGAAEVLSAVLVHKLHERKAKPGMRADFTGLDIPDR
                     FLFGCGMDYKGYWRNAPGIYAVKGL"
     gene            10553..11185
                     /gene="upp"
                     /locus_tag="P5537_10030"
     CDS             10553..11185
                     /gene="upp"
                     /locus_tag="P5537_10030"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HRV78420.1"
                     /translation="MPIHEIRHPLVRHKIGLMREGDISTKKFRELTAEIARLLAYEAC
                     KDFPLETVEIQGWAGPVQIEQIKGKKVTVVPILRAGLGMLDGVLDMMPSAKVSVVGIA
                     RDEETLQPVPYFEKFVGQLDERMALIIDPMLATGGSMVATVDMLKRKGCTHVRALVLV
                     AAPEGIALMDDKHPDVDIYTASIDSHLNEHGYIIPGLGDAGDKIFGTRHN"
     gene            11297..12544
                     /locus_tag="P5537_10035"
     CDS             11297..12544
                     /locus_tag="P5537_10035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-xanthine permease family protein"
                     /protein_id="HRV78421.1"
                     /translation="MREIPIQSAEPLWRQAISGAQILFVAFGALVLVPLLTGLNPSLA
                     LLGAGVGTLLFQLITGRQVPIFLGSSFAFIAPIIFSIQTWGIPATMGALACVSLMYFV
                     FAGLVWKHGADIVHRYMPPVVVGPIIMIIGLSLAAVGVNMAMGRSGDGKIELVPYATA
                     LTVAGISFGTTVLVAVFARGFLKLVPILCGVGAGYVAAILFGLVDFAAVGAAPWFVLP
                     QFVTPSFELAAILFMLPVALAPAIEHVGDVLAIGGVTGKDYTEKPGLHRTLAGDGAGV
                     LFAGLVGGPPITTYSEVTGALTLTKNYNPAIMTWAAVFAVILAFFGKFNALLASIPVP
                     VMGGIMMLMFGSVAAVGLNTLIKARVDLEEPRNLVIVSSVLVMGIGGLALNFDGLTLQ
                     GVSLCGVVAVLLNLILPKTRADA"
     gene            complement(12477..12878)
                     /locus_tag="P5537_10040"
     CDS             complement(12477..12878)
                     /locus_tag="P5537_10040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqjK family protein"
                     /protein_id="HRV78422.1"
                     /translation="MDSRHIELALRKQKLQLRAEAQRTDIAQRLAGIDGALDRVDSLR
                     DNLAWAKDKIPVLSVALLVVLAAKPRLTLRLAKRAWVGWLLMRQVRGGRLSALLPTAV
                     PLLRGLLAILRRRLESSEGSGSAAPRRRRTG"
     gene            complement(12892..13284)
                     /locus_tag="P5537_10045"
     CDS             complement(12892..13284)
                     /locus_tag="P5537_10045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HRV78423.1"
                     /translation="MSTEPRAPRPRLADSLHGIVDAGLQTAQTRLELLAVELQEEKLR
                     LTGLALNTVLAGLLLGFGLVFLMVFLTVLFWEEYRLLALGVSTAVCLGGGLLAASNAA
                     RAFRSGTKLFSASLAEFARDRAALKKPD"
     gene            complement(13289..13600)
                     /locus_tag="P5537_10050"
     CDS             complement(13289..13600)
                     /locus_tag="P5537_10050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF883 family protein"
                     /protein_id="HRV78424.1"
                     /translation="MATTLQPSKDKIVDDLKSLISDAEELLKLTADQQGGKLDDLRAR
                     INGRVAVAKDRLADAEAAIVDTGKKAVRATDDYVHENPWQSVGVAAGVAFLLGLLVSR
                     R"
     gene            13888..14397
                     /locus_tag="P5537_10055"
     CDS             13888..14397
                     /locus_tag="P5537_10055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HRV78425.1"
                     /translation="MIHKFAVTLALSLGLVSATAHAGEGIDTAAFFSSTLTGLDGGKV
                     AMEQFRGRPLVVNFWARWCGPCRDEIPELVKLRAEQGADGIEVIGVAIEENDKLEAVK
                     DFAKAYDMRYPVVIAAKDGIPLMKALGNPQAGMPFTVYIGRDGKAVGSKLGLVRRADL
                     EAAAQALLK"
     gene            complement(14635..15123)
                     /locus_tag="P5537_10060"
     CDS             complement(14635..15123)
                     /locus_tag="P5537_10060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrous oxide reductase accessory protein NosL"
                     /protein_id="HRV78426.1"
                     /translation="MKTLLALVFAAWTSFALAQAPAAALPKPGAKDLCPVCGMLTAKY
                     PNWVATIVYKDGHAHFFDGAKDMFKFWHDPGKYAAGHSREQIERIAVTEYYGLQAIDA
                     KGAWYVVGSDVLGPMGHEFVPLASAEDAADFLKEHKGARIVRFDEVSATLPVMLDEGR
                     FE"
     gene            complement(15120..15731)
                     /locus_tag="P5537_10065"
     CDS             complement(15120..15731)
                     /locus_tag="P5537_10065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrous oxide reductase accessory protein NosL"
                     /protein_id="HRV78427.1"
                     /translation="MDRREALKMSVLASIGLAVAGKANAQSACPGDGTPAQFTPRTAP
                     DPQPQVDDIAKYPKCPYCGMDRKQFHHSRMIVHYADDVADGTCSLHCSAISLSLNIDR
                     DPKALWVGDNAAAGETKPLVEVDKASFLVGSKLPGVMTARSKVAYGNADAAKASQAAN
                     GGELTDFDGALLAAYTDMSADVARIRKNRAERRRKMMEQQNKS"
     gene            complement(15826..16323)
                     /locus_tag="P5537_10070"
     CDS             complement(15826..16323)
                     /locus_tag="P5537_10070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HRV78428.1"
                     /translation="MRSFLLALACALLAACGAPDTGPKMGSAAPRFEATDLDGKLHRF
                     PEDFAGKPVVLDFWADWCRYCANSMTQIDRLQREHAASGLVVLAVNVAQDRATAAAFV
                     AQLGVGYPALLDPDSKITRQYGVQGLPITYFIDRDGRIGGKILGEADQKLLMSQLKRI
                     LPDAR"
     gene            complement(16337..17347)
                     /locus_tag="P5537_10075"
     CDS             complement(16337..17347)
                     /locus_tag="P5537_10075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78429.1"
                     /translation="MIFQPAIIALLLAAGLSLAMLATASPFAVQLIRHWDLGSGSERQ
                     LRLERLTYLFSMMVALVCGLQILSTLLFVFNADKMSVMFVGAMCAVGALNANAYGFPA
                     LYAQFALFFFASTWLAINRLDNQARDYPLTRLKYVLLLAYAPLAALVLYLQFNYFTRL
                     EADVITSCCGSMFSEEADTVASEVSAMAPRQAIALFYAGLGTAVLLALWHWRGAGLRV
                     WSGLAVGASSVLAFFAALMGIVAFVSLYIYEHPHHHCPFCILKPEYDYQGYLLYVPLF
                     AAAAAGLAAGVLTLFARRPSLATLAPQASARLAGIAAAGFALFLAVASFMVLSSNLIL
                     LE"
     gene            complement(17344..18042)
                     /locus_tag="P5537_10080"
     CDS             complement(17344..18042)
                     /locus_tag="P5537_10080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV78430.1"
                     /translation="MLELANIRKAFNQGQHNEYWALKGIDLEIPPARVNVLKGPSGSG
                     KTTLLTILGCLARPTEGRVRLKGEDISGLPERFLTEIRRSTFGFIFQQFNLVRGLSAI
                     ENIILPGYPTGTPRARLVERAEALLADMQLSHRRDAKVEWLSGGEQQRVAICRALIND
                     PEILVADEPTANLDSKLSAEFLAILRRLAEAGRTVILTSHDPLVVESEVVDRVYSLRD
                     GQLIEVVDTRRAWP"
BASE COUNT         2509 a         6120 c         6681 g         2903 t
ORIGIN      
        1 cccggtcgag atgcagctgc gcctgcgcca gggcatcgcc gagttcgagc gcagcctcgc
       61 ggtgctgcag gctgccagcc tcgcgccgga gctgggcgag gcgctggagg acgtcggccg
      121 cgtgtgggcg gattttcgcg atgcgctggg tgcggccgcg cgcccgccgg cgggtgcggc
      181 gcgggtgctt cagctgagcg aggacttcat caccgcggcc gatttcctca acgccgtggc
      241 cggcggcttc gccgcttccg gcagcctcta catggtcaac gtcgccgggc gcaaccgcat
      301 gctgtcgcag cgggtggcga agctcttcct cttcgagggc ttcgagggct gccccgaccc
      361 gcaagcgcag attgccgcct cgtgccgggc ctttgagcac aacctccagc gcttgcgcga
      421 gaattccggc gatttgcccg aactggaggc gcagatcgac gccacggcca gtctgtggtc
      481 gcgcttcgtt gccgcgctcg accccgcgat ccgccagccg catcgcatcg gccgggtgcg
      541 ctcggtgctc gacgagggag agcgcctgct gcgctacacc aacaccctgg tcaagctctt
      601 cgagcgcctc gcgcgctgag gctcgtccat cgttctgcgc gccgcctttc cgatacgggc
      661 gcgcgccctt ccctagccga ctcgtggagc aacccatgac cgcagcctcc agcccctcct
      721 tcccgaccac cccgcccgcc accgagccgg cgctgcgcct gatgccgatg ccggccgacc
      781 tcaactccgc gggcgacgtg ttcggcggct gggtcatggc gatggtcgac atcgccggcg
      841 ccctgcccgc gatccggcgt gcgcgctcgc acgtggtcac gatggcggtc aattccttcg
      901 tcttcaggca gccgatctcg gtgggcgacg tggtcagctt ccacgccgac gtggtcgccg
      961 tgggcaagtc ctcgatcacc gtcgatgtgc atgtgttcgc cgagcgccac ccggcggacc
     1021 ccgtggtggt caaggtgacc gaggcgcgca tgacctacgt cgcggtcgat cgcgagggct
     1081 gcaagcgcgt ggtgggtccg gagagcacct cgccccccgg cggcgagcgc ccgcccgcgg
     1141 acaaggagct cgtgctgcgg gtggtgccga tgccggccga cctcaacccc tcgggcgacg
     1201 tgttcggcgg ctggatcatg tcgatggtgg acatcgccgg cgcggtgccg gcgatccgcg
     1261 tcgcgcgctc caaggtcgcc accgtggcgg tggactcctt cgtcttcaag cagccggtgt
     1321 cgacgggcga catcgtcagc ttccacgccg aggtggtgcg cgtgggacgc acctcgatca
     1381 cggtcgatgt cgaagtctac gccgagcgcc acccggagag cccggtggtg gtgaaggtga
     1441 ccgaggcgcg cctgacctat gtcgcggtcg atgaattccg cgccaagcgc acgatcgggg
     1501 cgggctgagc ccgcgtcggt cgggcccgtt ccttcactcg ggcacgcaga tcctgccctt
     1561 tcgtgcggca cccagcgtct tcagcgcgag cagcaccacc accatggtga gcagcgcgag
     1621 caggatcagg ccgaggccgt ggtggaagcc cgagccggtg cgcgcgccca tctccagcgc
     1681 ggcgagcgtc atcgccgcga gcgggaagga ataggcccag gccgggatcg cgaagggcag
     1741 gcgcaggaag cgcagcgcat tgctcgccag cagcagggtc aggaagagcg cggtgaagta
     1801 gagcacgcgg gcgaaggcgt cgatctggtc gacgagcgcg acccaggcga ggaagccggc
     1861 ggccggcggg gcgatgagga tgaacagcgt cggcgtcagc cgctccggca gcggctcgtt
     1921 gaagaacagc cggtgcagca cgatggtcat cagcaccagc cagaacacca cgccgatgct
     1981 gaagaagaac cagctcaggt ccgccggtgc gaagccggta ccggcgatcg gcaccaggat
     2041 gttgcccacc accgggatga accaggccgg gttggcgtgc tcgagcttgt agcgcgggtg
     2101 gtggatccag ctgctcatcg ccgccagcgt gaacgccagg tgcagcgccg cgccgaggcc
     2161 ccagatccag gccgcgaagc cgggcagctc gcgcgcccac gccaccgcga gcaggatcag
     2221 tccgatcgag atcgccggaa agaaattgag cttgaccggg tgcatccagt ccgcgcgcac
     2281 cgcctgcgga tggcgcacga gcttcgccag gtacatcgcc gcgaggaaca cgaagagcgc
     2341 gctcgcgagc aggcgcagca cgttgccgat gaaggcgggg gcaccgccca gatggtgcag
     2401 cttgagccag gcgagcgcga gcccggtcag tcccatcacg atggcgaaga gggcgacggg
     2461 gaagtgctcg gttcggcaga tgcgcaaggt cgcgggcaca gtggccgggt gggcggatgc
     2521 gttcatggat cggttccgga ggaaatgctg gcaggtgcgg atcttgcgtt ggcaaggatg
     2581 ttcggtgccg cttcgacatg accggcgacg gcggatatca ccgttccaac cgccgccggc
     2641 atgcttgggg ctggggctcc cggcctgggt gcaccggatc gcaccagcat gcaagcattc
     2701 accgtgccag cgtgcagttg cggtcggggc ctcgcagcga cagacgcagt tccgcgttcc
     2761 agggcggaaa cggcagacgg ctcggtaggc atctgccaga attgacagaa ggatggcagg
     2821 cctccgcggt cgattcgccg gaggcttgag cgacctctgc cacttgcagg cgagtggccg
     2881 aggcgggagg acgggatgca ggggtcaggg gccgtgatgg cggcccgggt gcggcttctt
     2941 ggagaatgcg gatgaagatc gaaccgatga agaaccgcag gggtgccggc cccgacatcg
     3001 agggcgccgg tgcgggttcg ccgcgcaagg gggcgttcgg ccgcagcgtg caggccttcg
     3061 cgcgcatgct cccgatcctg atcgggacgc tgctgctcag cagcctgctg gtcgcctggc
     3121 tgccccgcac gccggtgctc ggctggttcg ggcgcagcga gtggctcgac gtgctgctcg
     3181 gcgcgagctt cggcagtatc gccatggggc acccggtcgc aggctacctg ctcggtggcg
     3241 agctgctcgc cggcggcatc ggcctcatgg cggtgagcgc gctggtggtg gcctgggtga
     3301 ccgtgggggt ggtccacctg cctgccgagg cgctcgcgct tggccgtgcc ttcgccctgc
     3361 ggcgcaacct gctgtgcttc gcgtcggcga tcgcggtggc ctggctcacc gtcgccagcc
     3421 tgcgcctggt ggggctcgca tgaagaaggc cgcacgcatc cccgcttcct ggctctacgt
     3481 cgcgttcggg ctcgccgcgc atggcgtcgg actcctcctc gatcctgcgg tcgcgcaggt
     3541 ggcgctggcg tccttcatcg acatgacgcg caccatcctg ccggtgctcg gcctcgtgtt
     3601 cgtgctgatg tacctggccg agcgcttcct gacgcctgcg cggacgcgct cgtggctggg
     3661 acgggactcg ggcacgaagg gctggctgct ggcgctcgcc gcgggcatgc tgtccaccgg
     3721 gccggcctat gcgtggtacg gcctgctcgc cgatctgcgc acgcgcggca tgcgcagcgc
     3781 gctgctcgcg gtgctgctct acgcgcgcgc gatcaagctg ccgctgctgc cgctgctcgc
     3841 gcattacttc ggttttgcct acatgctggt gctgtcgctc ttcatcgcgc tctttgccct
     3901 gctcaacggc tgggcgatgg agcgcttgtt ccccgagccc gaaaacgaat gaaacccgcc
     3961 ctctccacgc tcgaccatct gtccgtgggc gcaaccgccg tggtgcgcga gctcgatggc
     4021 gggaacgaat tctcgggcag gctcgccgcg atgggcctgg tcctgggcgc tgcgctgcag
     4081 gtgatgcaga actcgggcaa gggcccgatg ctggtgcggg tgcgcgacac ccggctggcg
     4141 ctcggtcgtg gcgaggcgca gcgcatcctg gtcgagcggg tgccgccatg aactcgcccg
     4201 tccggccgat tctgctcggt ctcgccggcc agcccaacgt cggcaagacc accgtgttca
     4261 atctgctcac cggcctggac cagcatgtcg gcaactgggc gggcaagacg gtcgagcgcg
     4321 ccgagggccg gctacgccac ggcgacgtcg aggccaccct ggtcgacctg cccggcacct
     4381 acagcctgag cgcgaactcg gccgaggagc gcgtggcccg cgatttcctg atcttcgaga
     4441 agccggatgc ggtgatcgtg atcgtggacg cctccgcgct cgagcgcagc ctctacctgc
     4501 tcgccgagct gcttgcgctc ggcctcgata cgccggtggt gctcggcctc aacatgaccg
     4561 acgtggccgc cgctcagggc atcaccatcg atccggcggt gttctccgcc gcgctcggtc
     4621 tgccggtggt ggcgctggtg gcgcgacgcg cccagggggt ggcggagctc accgaggcgg
     4681 cgctgcgcct cgcccgcgac ccggcctgct tcgcaccgct gcggccggag atcgccgagc
     4741 cgcatcgcga ggtcctcgag gacctgcatg cgctgctcgc ggcgcacgtg cctgcgccct
     4801 atcccgcacg ctgggtggcg ctgaaactgc tggagggcga cgccgagctg atcgcgctcg
     4861 cccgccgctg ggcgcccgag ccggtgtggg agcgtgcggc agcgctgctc ggcgagcacg
     4921 aggacgccat cctcgacatc gcggccggac gctacgcctg gatcgaacgc atggcacgcg
     4981 ccgcggtgag ccggccgcgc ctcggccagg tgagcttcac cgatcgtctc gatcgcgtcg
     5041 cgctgcatcc cgtctggggc ctggtgatgc tgctcggcgt gttcgccctc attttcggcc
     5101 tcaccttcga gctcgcaggg ccggtgcagg actggctgga gagcggcgtc atcgagccct
     5161 tcggcgcctg gctcgcggag cgcctcgccg gcgcgccgcc ctggctcgtg gggctgctgg
     5221 tggacggggt gcttggcggt gccggggtgg tgatcacctt cgtgccgctg ctcgcagtgt
     5281 tcttcgccgc gctcgcgctg ctcgaggaca ccggctactt cgcgcgcgcg gcctacgtca
     5341 tggaccgcta catgcaccgc ctcggcctgc acggcaagag cttcctgccc ctgtgcctgg
     5401 gcttcggctg caacgtgccg gcggtcatgg gcgcgcgcgt gatcgattcg ccgagcggcc
     5461 gcctgctcac catcctgctc gctccgctgg tgccttgcag cgcgcgcctg ctggtgctcg
     5521 ccttcttgtc gccggtgttc ttcggcgcgg ccgcgctccc cgtcgcgctc gtcttcatcg
     5581 cgctcaatct cgcgctggtc gcgatcctcg gcagtctcct cgaccgctcg ctgttccgcg
     5641 gcaagaaggt cttcttcatc atggagatgc cgctctacca cgtgcccagc ctgcgcacca
     5701 tcgggcgcca cgtgcgcggc cacgtgctcg ccttcctgcg caacgccggc agcctgatcc
     5761 tggtgttctc ggtgctgctg tgggcgctcg cgtggtttcc cggcgagggg ctcgagcaca
     5821 gctggctggc cggcttcggt cgcgcgctcg cgccgctggg tgaactgctc ggcctcgact
     5881 ggcggctgat cgtcgccctg ctggcgagct tcgtcgccaa ggagaacgcg atcgcggcgc
     5941 tcggcatcct ctacggcatc gaggccgagg gcgaggtgct cgcgcagacc ttggctgcga
     6001 gcgtgccgct cgcgtccgcg ctctccttcc tcaccgcgac catgctcttc gtgccctgcg
     6061 tggcgacgct ggcggtgatg cgcaccgaga ccgggagttg gcgctggccg ctgttcagcg
     6121 tgttgctgca tctggcgctg tcgctgcttg cggcggccgt ggtccatcgg ggctggatcg
     6181 cgctcgcggg gggctgaccg ccacaggcgg cgcgccgcgt gtggtcagcc ggcgtggccg
     6241 cgcacccagc gcacgatgtc cgccgcgccc atcgctcccg cctggcgagc aacctcgcgg
     6301 ccgccgcgga acagcgccag ggtggggatg ctacggatgc cgaagcgcgc cgccagcgcc
     6361 tggttggcct cggtgtcgag cttggcgagg cggacctgcg gctcgagcat gccggcggcc
     6421 tgcgcgaagg cgggcgccat cgtgcggcag gggccgcacc acggcgccca gaagtcgacc
     6481 agcaccggga tgtcgctgcg gccgacgtga cggtcgaagt tcgccgcgtc gagctccacc
     6541 gggtgggcgg tgaacagcgg cttgccgcac ttgccgcagt tgggcgcctc ggccaggcgg
     6601 gcggcgggga cgcgattgac ggcgtcgcag tgcggacaga ccaggtgcag ggcgtcggac
     6661 atggggggct ccggagtatt tcagacttcc ctgatatcgt ggcgaggcgg cgggattcaa
     6721 ggggccggtg tccatcggca cgggcgaggg aggggcgcgc aggccgtcgc gtctcgccgg
     6781 gatggcgtgc gccgcagcgt tcgggacgat aatgccggca tctcgttgcg aaggaggacc
     6841 accgatgaag cagccccgaa tcgtggtgat ggccggcagc cgccggcgcg aggccttgtc
     6901 gcgccgcgtg gcgcacgcgt gcgcacaggc cctgcgcgac gccggcgcgg aggtcgagct
     6961 ggtcgatctg gacgattacc ccgcgccgct ctacgacggc gacctcgagg ccgcctccgg
     7021 cctgcccgag ggcatcgtgc gcctgcagcg cgtgctgcac gcgagcgacg gcctgctggt
     7081 ggtcaatccc gaatacaacg gctcgctcac gccgctgctc aagaacacgc tcgactggtg
     7141 ctcgcggccc aaccccgccg accccgagcg ctccggcggc aaggtgtacg cggggcgggc
     7201 ggcggcggtg gtggggagtt cgccgggcgc gctcggcggc atgcgggtgc tgttccacgt
     7261 gcgcgacgtg ctcggctacc tcggcatgca ggtgatcccg cagcagctcg cggtgggcaa
     7321 ggccggcgag gcggtcggcg ccgacgggcg cctggatgac gctgcccagc agggcatgct
     7381 ggaggggctc gcggcggcgc tggtggatac ggcgcgccga atgcgcagct gagggttttt
     7441 cgcgcgcgaa gcttgcggcg cggatgcttc gcagccctcg ggggtgcgcg gccactcggg
     7501 gcggccggtc gcgggcggtg gcctcagtcc gcctttccgt cggccttttc gtcggccttt
     7561 ccgtccgccg ttccgtccgc cttccctgcg gcggcttgcc cacgcaggcc gcgcacggct
     7621 gcgcgggcct gcgcgaacac acgctcggct tcttccgggt cgaagtccgt ggcgtaacgc
     7681 ttcttcaccc cctgctcgtt gagcagcagg tggacggagg gctgcacgcc gcgctcggcc
     7741 aggctgctgc gcgtgcattc gagcgcgcag ccgtcgaggg cgaggatggg gcggccggag
     7801 cgggcgatgt tcaccaggtt cggcacgttg ccgccgacgc cggcgatgca ggacatctcg
     7861 gcctcgccct cgcgatccag gcgcagcgcc acgtggttgg ccatctgcgc ggcgctcgag
     7921 cacccggagc aggaatagac gagcggcagg ttcttcttgc ggccagccat ggcggggtcc
     7981 tcgggggggc gtgttggggc aaacagttta ctacgtgccg ccggcgtacc ctgcaggtca
     8041 cgtattcgcg atcgtgcctg ccccgcttcg cgggcaagcc tgcgaagcgg cgcgcgtcca
     8101 gcgccagcgg ggtggcggct gcggagcatc gcaggccacg gttacaatcg aacgatcgcg
     8161 gctgccgcgg caggtggtgc ccgcgggtgg cggcgccgcc ctcacaaaga gcgatcccga
     8221 cgtgaatccc cgacgacagc attaccgcgg ccgcaacccg gcgcgcgccc acaacatcgc
     8281 cgagctgcgc acgatggcgg cgcgccggct gccgaacttt tgcctcgaat acctcgaggg
     8341 cggcggcgac gatgagctcg cgctcgcgcg caaccggcgt gcgctcgacg acatcctgct
     8401 gctgccccgc accctggtgg acgtgtcgcg gtgcgagctc gcggtagcgc tgttcggcac
     8461 cgacatcgcc atgccggcgg tgatcgcgcc caccggcttc aacggcctgc tcacccacga
     8521 aggcgaccgc gtgctcgccg aggcggcgcg cgcggcgggc atcccgttct gccagagcat
     8581 ggtgtccacc gtggcgctgg aggacatcgc cgccaccggc gtgcgccact ggatgcagat
     8641 ctatcccttc aaggaccgcg acaacctcgc cgcggtggtg aagcgggccg agcacgccgg
     8701 ctgcgaggcg atcgtgctga ccaccgacgc ctcggtgttc ggcaaccgcg agtgggaccg
     8761 ccgcaactac cgcgcgccga tgaagctcac ctggcgcaac gtgctcgatg tcggcctgca
     8821 cccgcgctgg atcttcgacg tgctggtacc gcgcggcatg ccacgcttcc gcaacctcgg
     8881 cgacttcctg ccgccgggca tggacagcgc gaggaacgcc gctgccttcc tcgccgcgca
     8941 gatggacacc tcgctgacct gggacgatgt gcgccgcctg cgcgagctgt ggccgcgccg
     9001 gctactggtg aagggcgtgc tgctgcccga ggacgcgctg cgcgcgaagg aggcgggcgc
     9061 cgacggcgtg gtggtgacga accacggcgg acgccagctc gacgccgcgc cggcgccgat
     9121 cgagaccctg gccgcggtgc gccaggcggt gggggcggag atgacggtga tcgtggacag
     9181 cggctttcgc cgcggcagcg acttcgtcaa ggcgcgcgcg ctcggcgcgg atgcagcgat
     9241 gtcggggcgg gcgaccctgt acggcctcgc cgccgccggc gcgccgggcg ctgcgcgcgc
     9301 gctggagatc gtgcgcagcg agatggagcg cacgctcggc ttgatcggct gcgcgcgcat
     9361 ggcggaggtg gacgcgcgct tcgtcggtcg cggctgagcg ccgcgggagg gagtgtggag
     9421 cgggggggga tcagaccccc cagaccaccg gcgtctcctc gcgcagcgat tcttccagca
     9481 tggcgagcag cggccaggcg cgctgggcga ggccgaccgg cgcggccatg ccggtgttgc
     9541 cggcttcctt ttcggcctcc tcgtcggcgt ggccgcgctg gcgttcgagt tcggcctggc
     9601 gggcgcgctc ctcctcgatc gcggccttga ggcgggcgat ggcctcgggg agttgttgta
     9661 cggtgaggat gcccttggcg tcggcggggt ccttgccgag gatgccgatg agcttcttgg
     9721 cggcgtcgcc gaacatgatt acgtcggcgc tcgcgtggga cttgaaggtg accagcatgg
     9781 ggtgtcgctc ctttattaca ggcccttgac ggcgtagatg ccgggcgcgt tgcgccagta
     9841 gcccttgtag tccatcccgc agccgaacag gaagcggtcg gggatgtcga ggccggtgaa
     9901 gtcggcgcgc atgccgggct tcgccttgcg ctcgtgcagc ttgtgcacca gcaccgcgga
     9961 cagcacctcg gcggcgcctt cttccttcag gtgcgcgatg atggcctcga gcgtgtggcc
    10021 ctcgtcgagg atgtcgtcga gcaccagcac cgtgcgcccg cgcaggtcct gggtggggcg
    10081 cacgcgccag tcgagcaggg tgccctggat cgcgtggccg tagcgcgtgg cgtgcaggta
    10141 ggcgagctcg agcgggaagg gcaggcgcgg caggatgcgg ccggcgagga tcaggccgcc
    10201 gttcatcacc gcatagacga gcgggttggc gtcggcgagg cgggcggtga tctcggccgc
    10261 catgcggtcg agcgcagcct ccacggtggc ggcgtcggcg aggcagtcgg cctcttcgcg
    10321 cgcgcgcttg atttcttcca ggttcaggga catgtcgatg agctgcgggc gcttgccctg
    10381 tgcgttttcg gacgcgtcat tctagcgccg atccccggcg ggcgccgcct tcgccggcgc
    10441 gccgggaccc gcggcgtgct gcgatgcggc aggctgtggt ttgtgcgctt gtgcgccggc
    10501 cggcggcgcg gtaaaagagg cggatcttcg tcccgccgcc ccggaaaccg ccatgcccat
    10561 ccatgaaatc cgccacccgc tcgtgcgcca caagatcggc ctgatgcgcg agggcgacat
    10621 cagcaccaag aagttccgcg agctcaccgc cgagatcgcc cgcctgctgg cctacgaggc
    10681 atgcaaggac ttcccgctcg agacggtcga gatccagggc tgggctgggc cggtgcagat
    10741 cgagcagatc aagggcaaga aggtcaccgt ggtgccgatc ctgcgcgccg gcctgggcat
    10801 gctcgacggc gtgctcgaca tgatgccgag cgccaaggtc agcgtggtcg gcatcgcccg
    10861 cgacgaggag acgctgcagc cggtgcccta cttcgagaag ttcgtcggcc agctcgacga
    10921 gcgcatggcg ctgatcatcg acccgatgct cgccaccggc ggctccatgg tcgccaccgt
    10981 ggacatgctg aagcgcaagg gctgcaccca cgtgcgcgcg ctggtgctgg tggcggcgcc
    11041 cgagggcatc gcgctgatgg acgacaagca ccccgacgtc gacatctaca ccgcgagcat
    11101 cgacagccac ctcaacgagc acggctacat catccccggg ctgggcgacg ccggcgacaa
    11161 gatcttcggc acgcggcaca actgattcca tggcgacggc gggcgatggc ccgtcgcgtc
    11221 atcaccgctt catccataac gacaaccatg ccagctgcgc gccaccccgg ccgcgtgcgc
    11281 ctggcggaga accctcatgc gtgaaatccc catccagtct gccgagccgt tgtggcggca
    11341 ggcgatctcc ggcgcccaga tcctcttcgt cgccttcggc gcgctggtgc tggtgccgct
    11401 gctcaccggg ctcaatccct cgctcgcgct gctcggcgcc ggcgtcggca cgctgctgtt
    11461 ccagctcatc accgggcgcc aggtgccgat cttcctcggc tcgagcttcg ccttcatcgc
    11521 gcccatcatc ttcagcatcc agacctgggg tatcccggcc accatgggcg cgctcgcctg
    11581 cgtgtcgctg atgtacttcg tcttcgccgg cctggtgtgg aagcacggcg ccgacatcgt
    11641 gcatcgctac atgccgccgg tggtggtggg gccgatcatc atgatcatcg gcctgtcgct
    11701 cgccgcggtg ggcgtcaaca tggcgatggg gcgcagcggc gacggcaaga tcgagctcgt
    11761 gccctacgcc accgcgctca ccgtcgcggg gatctccttc ggcaccacgg tgctggtggc
    11821 ggtgttcgcg cgcggcttcc tgaagctggt gcccatcctg tgcggggtgg gggcaggcta
    11881 cgtggcggcg atcctgttcg ggctggtgga tttcgccgcg gtgggcgcgg cgccctggtt
    11941 cgtgctgccg cagttcgtca ccccgagctt cgagctcgcc gccatcctgt tcatgctgcc
    12001 ggtggcgctg gcgccggcga tcgagcacgt cggcgacgtg ctcgcgatcg gcggtgtgac
    12061 cggcaaggac tacaccgaga agcccggcct gcaccgcacc ctggccggag acggcgccgg
    12121 cgtgctgttc gccggcctcg tcggcgggcc gcccatcacc acctattccg aggtcaccgg
    12181 cgcgctgacg ctgaccaaga actacaaccc ggcgatcatg acctgggcgg cggtgttcgc
    12241 ggtgatcctc gccttcttcg gcaagttcaa cgcgctgctg gcgtcgatcc cggtgccggt
    12301 catgggcggg atcatgatgc tgatgttcgg ctcggtggcg gccgtggggc tcaacacgct
    12361 gatcaaggcg cgcgtcgacc tggaggagcc gcgcaacctg gtgatcgtgt cctcggtgct
    12421 ggtgatgggc atcggcggcc tggcgctgaa cttcgacggc ctgaccctgc agggcgtcag
    12481 cctgtgcggc gtcgtcgcgg tgctgctgaa cctgatcctt ccgaagactc gagccgacgc
    12541 ctgaggatcg ccagcaggcc gcgcagcagc ggcacggcgg tgggcagcag cgccgacagc
    12601 ctgccgccgc gcacctggcg catcagcagc cagcctaccc acgcccgctt cgcgaggcgg
    12661 agcgtgagcc tcggcttcgc ggccagcacg acgagcagtg cgaccgacag caccggaatc
    12721 ttgtccttcg cccacgccag gttgtcgcgc agcgagtcga cgcggtcgag cgcgccgtcg
    12781 atgccggcga ggcgctgcgc gatgtcggtc cgctgcgctt cggcgcgcag ctgaagcttc
    12841 tgcttgcgca gcgcgagctc gatgtggcgg gaatccatgc ccggcgcgcc ctcagtcggg
    12901 tttcttcaag gccgcgcggt cgcgtgcgaa ctcggcgagg ctggcggaga acagcttcgt
    12961 gccgctgcgg aaggcgcgcg ctgcgttgct cgcggcgagc agcccgccgc ccaggcagac
    13021 tgcggtcgag acgcccagcg cgagcaggcg gtattcctcc cagaacagta cggtcaggaa
    13081 caccatcagg aagaccagcc cgaagccgag cagcagcccc gccagcaccg tgttgagcgc
    13141 gaggccggtg aggcggagct tttcttcctg gagctcgacc gcgagcagct caagccgcgt
    13201 ctgcgccgtc tgcaggccgg catcgacgat gccgtgcagg ctgtcggcga gacgcggcct
    13261 gggcgccctg ggctcggtgc tcatcgactc agcggcggct gaccagcagg ccgagcagga
    13321 aggcgacgcc ggcggcgacg ccgaccgact gccaggggtt ctcatgcacg tagtcgtcgg
    13381 tcgcgcgcac ggccttcttg ccggtgtcga cgattgcggc ctcggcgtcg gccaggcggt
    13441 ccttggcgac cgccacgcgg ccgttgatgc gcgcgcgcag atcgtcgagc ttgccgccct
    13501 gctggtcggc ggtgagcttg aggagttcct cggcgtccga gatcagggac ttgaggtcgt
    13561 cgacgatctt gtccttggag ggctgaaggg tcgttgccat gatggttctc ctgagtgtgg
    13621 tcggtaaaaa tggcctgaag cgtttcgtgc catgcctgca gcaagcctac cccggggggc
    13681 tcccgcccgc aatgaacgat gcgtaagcgg atgctgaagc cggtgtaggc ggatgtcgcg
    13741 tcgcagcggt cgagccgacg cgggcgggtg cgccgggcgg cgatgcttgg caaaatggag
    13801 ccgatgtcgt cgggcgcctc ggtgcccgct ccctgccggc atggcacacg ccatgacgga
    13861 ctcccgtctg ccaggaaagg tttcccgatg atccacaagt tcgccgtcac gctcgccctc
    13921 agtctcggtc tcgtctccgc caccgcccat gccggcgagg ggatcgacac cgccgccttc
    13981 ttctcgtcca cgctgaccgg cctcgacggc gggaaggtgg cgatggagca gttccgcggc
    14041 cgcccgctgg tggtcaattt ctgggcgcgc tggtgcgggc cttgccgcga cgagattccg
    14101 gaactggtga agctgcgcgc ggagcagggc gcggacggga tcgaggtgat cggcgtcgcg
    14161 atcgaggaga acgacaagct cgaggcggtg aaggacttcg ccaaggccta cgacatgcgc
    14221 tacccggtgg tgatcgccgc caaggacggc atcccgctga tgaaggcgct cggcaatccg
    14281 caggcgggga tgcccttcac cgtgtacatc gggcgcgacg gcaaggcggt cggcagcaag
    14341 ctgggcctgg tgcgccgcgc cgacctcgag gctgcggcgc aggccttgtt gaagtgacgg
    14401 gaagaacggg cgcgggtgag ggctgaaggg ccgctttcgc gcctgccggc gctcctacat
    14461 gaaccccgag gcgcgacggt ttcctgtagg agcgccggca ggcgcgaata cggcgctcca
    14521 gcggtgtcgc gtgctgcggc cgcgcttctg gcctcggggg tttatgtagg agcgcctgcc
    14581 ggcgcgaata cggcggtcca gcggcgtcgc gtgcccagct tcggatcccg ggccctactc
    14641 gaagcgccct tcgtccagca tgaccggcag cgtggcgctc acctcgtcga agcgcacgat
    14701 gcgcgcgccc ttgtgctcct tgaggaagtc cgcggcgtcc tcggcgctgg cgagcgggac
    14761 gaactcgtgc cccatcggcc cgagcacgtc cgagccgacg acgtaccacg cgcccttggc
    14821 gtcgattgcc tgcaggccgt agtactcggt caccgcgatg cgctcgatct gctcgcggct
    14881 gtggccggcg gcgtatttgc ccgggtcgtg ccagaacttg aacatgtcct tggcgccgtc
    14941 gaagaagtgg gcgtggccgt ccttgtaaac gatggtcgcc acccagttgg ggtacttggc
    15001 ggtgagcatg ccgcataccg ggcagaggtc cttcgcgccc ggtttcggca gtgcggcggc
    15061 gggggcctgg gcgagcgcga agctcgtcca ggccgcgaag acgagggcga gcagggtctt
    15121 catgacttgt tctgctgctc catcatcttg cgccgacgct cggcgcggtt cttgcggatg
    15181 cgcgcgacgt cggccgacat gtcggtgtag gcggccagca gcgcgccgtc gaagtcggtg
    15241 agctcgccgc cgttggccgc ctgcgaggcc ttggccgcgt cggcgttgcc gtaggcgacc
    15301 ttgctgcggg cggtcatcac gccgggcagc ttgctgccga ccaggaagct cgccttgtcg
    15361 acctcgacga gcggcttggt ttcgcccgcg gcggcgttgt cgccgaccca cagcgccttg
    15421 gggtcgcggt cgatgttgag cgacaggctg atcgcggagc agtgcagcga gcaggtgccg
    15481 tcggcgacgt cgtcggcgta atgcacgatc atgcgcgagt ggtggaactg cttgcggtcc
    15541 atgccgcagt acgggcactt gggatacttg gcgatgtcgt cgacctgggg ctgcgggtcc
    15601 ggcgcggtcc tgggggtgaa ctgcgccggc gtgccgtcgc ccgggcaggc ggactgggcg
    15661 ttggccttgc ccgcgacggc gaggccgatg ctggcgagga cggacatctt gagggcttcc
    15721 ctgcgatcca tggctggtct cctgggttga gtctggctgg tggatgggtg aggcgaggtg
    15781 ggtccgatcg tgcgcgcgtg cgcgacggtg cgccttgatg aaggtctagc gggcgtcggg
    15841 gagtatgcgc ttcagctgcg acattagcag tttctgatcc gcctcgccga ggatcttccc
    15901 gccgatgcgg ccatcgcgat cgatgaagta ggtgatcggc aggccctgca cgccgtactg
    15961 gcgggtgatc ttcgagtcgg ggtcgagcag cgccggatag ccgacgccga gctgggcgac
    16021 gaaggcggcg gcggtggcgc ggtcctgggc gacattcacc gccagtacca cgaggccgct
    16081 cgccgcgtgc tcgcgctgca ggcgatcgat ctgcgtcatg ctgttggcgc agtagcggca
    16141 ccagtcggcc cagaagtcga ggaccaccgg cttgccggcg aagtcctcgg ggaagcgatg
    16201 cagcttgccg tcgaggtccg tcgcctcgaa gcgcggtgcc gcgctgccca tcttcgggcc
    16261 ggtgtcgggt gcgccgcagg ccgcgagcag ggcgcaggcg agggcgagca ggaaggatct
    16321 catcggtggc acgccttcac tcgagcagga tcaggttgga gctcagcacc atgaagctcg
    16381 ccaccgcgag gaagagcgcg aagcccgccg cggcgatgcc ggccaggcgc gcgctcgcct
    16441 gcggcgccag cgtggcgagg ctgggccggc gcgcgaacag ggtcagcacg ccggccgcca
    16501 gtcccgcggc ggcggcggcg aagagcggga cgtagagcag gtagccctgg tagtcgtatt
    16561 ccggcttgag gatgcagaac gggcagtggt ggtgcgggtg ctcgtagatg taaagcgaca
    16621 cgaaggcgac gatgcccatc agcgcggcga agaaggcgag cacggaggac gcgcccaccg
    16681 cgagcccgct ccacacccgc agccccgcgc cgcgccagtg ccacagcgcg agcagcacgg
    16741 ccgtacccag gccggcgtag aacagcgcga tggcctggcg cggcgccatc gcgctgacct
    16801 cgctcgccac cgtgtcggcc tcctccgaga acatgctgcc gcagcacgag gtgatcacgt
    16861 cggcctcgag gcgggtgaag tagttgaact gcaggtacag caccagcgcg gcgagcggcg
    16921 cgtaggcgag cagcagcacg tacttgaggc gggtgagcgg atagtcgcgc gcctggttgt
    16981 cgaggcggtt gatcgccagc caggtggagg cgaagaagaa cagcgcgaac tgcgcgtaga
    17041 gcgccgggaa gccgtaggcg ttggcgttga gcgcgcccac cgcgcacatc gcgccgacga
    17101 acatcaccga catcttgtcg gcgttgaaca cgaacagcag cgtcgacagg atctgcagtc
    17161 cgcacaccag cgccaccatc atcgagaaca ggtaggtcag gcgctcgagg cgcagctggc
    17221 gctcgctgcc gctgccgagg tcccagtggc ggatcagctg caccgcgaag ggcgaggcgg
    17281 tcgccagcat ggccaggctc aggccggcgg ccagcagcag ggcgatgatg gcgggctgga
    17341 agatcatggc caggccctgc gcgtgtcgac gacctcgatg agctggccgt cgcgcagcga
    17401 atacacccgg tcgaccacct cggactccac caccagcggg tcgtggctgg tgaggatcac
    17461 cgtgcgcccg gcctcggcca gccgccgcag gatggcgagg aattcggccg agagcttgct
    17521 gtcgaggttg gcggtgggct cgtcggcgac gaggatctcg gggtcgttga tgagcgcgcg
    17581 gcagatcgcc acgcgctgct gctcgccgcc ggagagccac tccaccttgg cgtcgcggcg
    17641 gtgcgagagc tgcatgtcgg cgagcagcgc ctcggcgcgc tcgacgagcc gcgcgcgcgg
    17701 ggtgccggtg ggatagccgg gcaggatgat gttctcgatc gccgacaggc cgcgcaccag
    17761 gttgaactgc tggaagatga agccgaaggt gctgcggcgg atttcggtga ggaagcgctc
    17821 gggcaggccg gagatgtcct cgcccttgag ccgcacccgg ccctcggtgg ggcgggcgag
    17881 gcagccgagg atggtgagca gcgtggtctt gcccgagccc gaggggccct tcagcacgtt
    17941 gacgcgcgcg ggcgggatct ccaggtcgat gcccttgagc gcccagtatt cgttgtgttg
    18001 gccctggttg aaggccttgc ggatgttggc gagttcgagc atcgcgtcag ctccgcatca
    18061 cggtgtcggg gtcggtggtg gccgcgcgcc agatgggcat cagcgtggcg gccgtgtagg
    18121 gcagcaccga gaacacgaac agcgtcgcca cctgcaggcc gtcgatcttc ggcgtgagcg
    18181 cgaagctcgg gtaaagcacc gcccagccct gca
//
LOCUS       DAOTIN010000058        17981 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_3759_length_17981_cov_7.458887, whole genome shotgun sequence.
ACCESSION   DAOTIN010000058 DAOTIN010000000
VERSION     DAOTIN010000058.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 17981)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 17981)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17981
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3759_length_17981_cov_7.458887"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(263..2173)
                     /locus_tag="P5537_10085"
     CDS             complement(263..2173)
                     /locus_tag="P5537_10085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78431.1"
                     /translation="MKLRSLHLCLALLALVPASLPAAERAVAATSPGKVSAARSAPIS
                     TTLLEAFDPPHASTAEAATAGGADTATAGVAGTKVEAEAAEAEYYWLLTGYGVRLAFD
                     LASLPAGLSAAQMQRCVLRVVASEVRYVREHEAVAAVVELAVRRVGDTRPLAALRDLR
                     PDRPVSLNPDNGRLCEAVAEAAAAPARRLELELYTATSRASSLLHGRASAEDGVRQAS
                     HAPRLVIQYAPDAAAAASGWRQPQHDAGHSGRGDFKPARSPGGFELQALPLPAVGEDA
                     SPGLLAERPLLWRDQVIAVQKRGRLNYLVALDGKGGLMWSSEIGGGVVQRAPVISPQG
                     LLYLVTEDAVRAWDLEAGGALRHTFRLPEVAAQMPVRLSPFTKPTVGEDGSLYLVLGD
                     GFDGVLGLDARLRPFLFFALNEAAGSRMPGSAALSIDGRRLAVPTGEGAVVLDLHEPA
                     EVERLAFGDAAAAAGWRHHLPVAGGRIGEWIFSGYDEEDGTGRVWAFAGRAPRWQASG
                     GTSTQPVLAPDGRVWFVQDGALNVRGFGPGDAGRRFGAGLCASSNPVMDGAGNLFFWC
                     SGTLYGFASDGRALFAGQGFANAPEENLALALGTDGSLWTANANGGALFVFRPHFARS
                     PAPRPTPRRPGR"
     gene            complement(2210..4225)
                     /locus_tag="P5537_10090"
     CDS             complement(2210..4225)
                     /locus_tag="P5537_10090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78432.1"
                     /translation="MALACHLRSRLAAGVPHRRGGVATAEACMTDAAMGLVARIACMG
                     DFVVGARSAANRLTLRIDYRGGQGLACARWPALVLRCGVGGGEGDLVRDAAQLRRWSC
                     QASAGWVAQWRLPPAWPEGCELWLLRRGDALLQPGDALEVVFSGAASDARPGLAALEL
                     RLQARGDAAAAAVIPLQLAKRASAAGVLGFACVPEAAAMNLPGDVVELRWRTCGLSDL
                     SLLRDGLCIAEGLADAGHRRVVAGVGDAEFALRGWDEAGQRHEAGLRVRALRPGWQRW
                     PCMLATREGRRLGVPATAATSGEALPLRLFGVAGGMLYASVALPGVGGSCVLLCRARH
                     ALGPWELVGAAGAGKGGAEGAAEMAVEGAGPFPAFPHGCERLPGVLFRGRLWLLGAPS
                     AARGRCGSKVWSLDVGAREPRWRDHGEAPWCARRAHGVAVFEDRLWVFGGIDSAGASL
                     DDAWAATQEPAEGAVVWTPAEEGKPVDQAAVPTLDWQVQAAGGPRERPCGAAQPVLHD
                     GRLWLFGRAGSASAGEVGSEPVGEGSEPLREEDEERRECFDLWSFDGLRWERSFLLGD
                     LIEGQVLAAALASDGRSLHVFAWTSRHADAARADAERVEAIALRLVDAPAKRWAVLPC
                     EDLQGLVPAAIEDFQVLALRAGALVLRLLATENECAADRALRLYFPA"
     gene            complement(4138..8280)
                     /locus_tag="P5537_10095"
     CDS             complement(4138..8280)
                     /locus_tag="P5537_10095"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78433.1"
                     /translation="MSADFSRPCLLVPMNVEALAVGAASAAIDLSVDFSALAEGGPCL
                     GSLLGREPFQETPRALAPGVYLHWSLPDGLTHAPESAAGEDAGARMPAIPNRWLVLRF
                     AAAGAACRGWVVESDTLTGVREGRAWPRRVVDASAPLARDELIVHLGRCVPLEAWSES
                     HPARQPGITALGYGDPVFAASFPHGRGVLGFHDEEVCALQEAELHYLVLGWYSAPKDD
                     DPLAACLHKALAARDWNAWKDLFEGCAWVYPGLDELLAKQDERHRAEERAQQASAHAR
                     RVAQRRRGAVPRDAVRWLAREYVEARRQAQARKAELDTAWHHLPGRILCHGLLAGLRW
                     RGAAAAYGGPPRGAPFRAALGEHGAEAMAALLGAQPGVPAQHAAYFEALQHDLDPLLE
                     RPGGAEHLAHELHARRFQPLSRASGWEIVEREPAPLRAGRPARKAIPGIVRRALAALE
                     RQQREADALARELDSLGQALYLAWYQRGLASFDCDPEAIERWRAEESALLAKIAAQRE
                     RLAARVDAQGIPRGRPLERVRALVERLLPGYELRRVDGERFHRPRDPVLLLAGPAFAD
                     PGRHGKDGRHRADGRLHCRTSACLAQGEAAAAKDEPTIGALADAELQRRGIPAPAARL
                     LREAIEIARADDAVAVALADATETGRASAPPASVGTPADGSESGSGSGSGSGAPGSAD
                     SVPAAIACTRWCGNPWLPLLLQWRVSWSELARAGEGAAALAGWRLGAHGDGYERSAEA
                     VPGREHVFTGTSLMTPGVADSLQRRLCEAGVEVAAIDVLGQSLDGLMDGLLARCARPE
                     LPPLEAEGHAGPLRPAPHAAQLEAADGLSPLRDARLLPLRAGLLRIERLRVIDAFGRF
                     MELQPEGGGALPVVLPPRLRGPGGAALFEPRLVQAARLVVDWPAPARWRGGGRNPDGA
                     AGQAARVQEDAAAEPGEGEACAWILPDRIGGTLALLDAAGNLLGALQAMRGKADAHGV
                     GGRTRPIDGFRWVATLGPHASTAADAPGETAFDPADPLADRGADPLVRELVRELLRWQ
                     GASGARLADLLDALQQAAGELAPDADDPAVGLLVGRPLALVRARLRLELDGLPAHDPA
                     SAQGEGRCGGVEAIAFPLRLGDFGGSGEDGLAGFFLADEPGRFHPAWGLRTGEGRPEL
                     RERSEPVLSIERPLELILLMDPERGFTVTSAVLPRAHFRPPGAGERVRARSLMFFTGP
                     VLGACSELRLPRPSDLYGQWAWNHHPRVGVRAEREVIDTAASGSVTFPPDLALAEGWL
                     RLEAVALAIDGFGVVDAAVAAPSAGAAQDAVAGFELPPQLPATLAWTVSGADAIELSG
                     PDGRVLLCTAAAPLPSTWALAQPLAGRYRLRAWRWLATSDRDSPPACRIAEVELRLRR
                     PA"
     gene            complement(8270..10900)
                     /locus_tag="P5537_10100"
     CDS             complement(8270..10900)
                     /locus_tag="P5537_10100"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78434.1"
                     /translation="MSSPSVEPGQIRFADACLPALAAGDYRLRMKQEVRAAPFGPFPM
                     HSKPYASELVFSVDGPRFRLEPAEIHATYPPPGAAGAFADALPHVVFTRRTLPWERTL
                     DGHSQAEPPRPWLALLLLDEDELLAGVEQGESRLPPCVPPRPLPVCGGADAREDSLLF
                     AFDPQGKRLDRLRVPALGQEGDERARLLARHGGERCQALDMPAKLFAAIAPRIADLPW
                     LAHARLIDTGDKEIFRGHDQGWYAVAIGNRMPSPGRAHHAFLVSLEGFADVLTDASGL
                     EGYDSVRLAVLASWRFECLGRGDFKARMRGLDAGAFERARTAGEEAGNAAAGDQRAAA
                     EPDAWLHLPLPPAEPAHAAEAAPVRPAGEAPTPAALVRGALARGYAAFDHRLRHGEHT
                     VSWYRGPLVPLEYSQPRQVQRLVRCSDELLRYDPECGMFDTTYAGAWQLGRLLALQNR
                     GFVLALERARLGLRRRLAELRHAPTVAGLAQRAGARHESDEAGRPGRLRETLALACAE
                     AIEAGVGAVRAGLGPETAPIAPAASAPTAAPVLRATELQTMLAEASAWLGRLVLLYGV
                     PLHNLVPDEDMLPPETLRLFFLDPNWIQALVQGACSVGNADCGDLLVNRVMRFCLSPD
                     VAEPAAERDLPVEASAAGEAGRAAAGERARLRAECEGRKTDSKKAPEKTQEEDSEEDS
                     EKASANPPAGLDWPLGGFLLRSAVVEGWRGLEIEGWLGDAKLPALRIEQLADDVMLVL
                     FNGMPDMVEIRQPREGLHFGLSPKADGAGFTRTLRCAQTGAAQTSGALIEVPMRGESQ
                     GDMNACAAPGVIDIDALARALRAALEPGGAASASIGAGGAVPDGGVAAPFGPGDFAMQ
                     MIEAAGAFRFRIARGGAGVG"
     gene            complement(10929..13907)
                     /locus_tag="P5537_10105"
     CDS             complement(10929..13907)
                     /locus_tag="P5537_10105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78435.1"
                     /translation="MSTPGDSRPATPTTVELGVDLRVGGRPLVLRGALADGGLTSLAG
                     TLQGEATDTLGGLLIALGHAFAGPRAALDALGGGALAEIHFEAVELAYRSAGTPSVTL
                     STTLGAGSGRTRIVVAKLLPAPGRAEDEGGLVAGFELELEPRPIGDKGLSELIGGVVV
                     ERLGVFHASRDCSDLHLEPPTAPGAFAPLVEPAGPARSLHAGLNLSGRVLIGGVDLLE
                     GLGRASSEPGDGGDTLDAQAGDAEARPEPSATPPAPPPPEAPLPTRGKAFWKRVDKRI
                     GPLTFRRVGLVYESSRLAIALDAGLRIGGLSFELVGFGVDCPLAALLKGPRAAMEGLG
                     VRLEGAMLGLETGAIAISGGLTRAAGETLRLDGSLRVSTPVLTVSAIGSYERIEGAHS
                     FFAFAALHKEIGGPPFFFVTGLCLGIGIHRRLTLPPIGQVHSFPLLRAAAEPDFLGKD
                     ADPRRIGALVDTWLAPEHDSMWIAGGVRFTSFGIVESVAMLSVAFGNRLEIGVLGLSR
                     LELPRKAGGDAAMACVEMELRVVIAPDDGLVAVEGRLTENSFVLRRDFRLSGGFAFFA
                     WYAGPHAGDFVVSVGGYHPAFQVPAHYPRPERVAFNCQIGQVTISGQCYFALCPAAIM
                     AGGSLSIVYASGGIRAWLVARADFLMQWKPLHYEASVAVSLGVQLNIKIWFVRIRLSI
                     ELGAAIALYGPPLAGSVRVSLYVVSFTVGFGPPRTLPPPMVWESDDPERSFAHSFLGN
                     PDVTRISVVDGLLDTPAAPPGGVPQRPVLQAHRLYLRCQSSVPATALFFGDAEVPPRE
                     AGSWPQLGVQPMGLGRFQSEIRVTLEALDADGAVRTDAQAELDVLPLTASVPCALWSP
                     FRLGPAILSGRQLIDGAPVGIELRGRVDPDTRIGPALELEAFAYDRFEYRCRAVGALR
                     PATALPGSRHGLGDTIMKDAVVERRRAIVDCLNAGRRVRRLSADAELPILAAAPAHVL
                     DVEPLMARVGQDVPRMFAEI"
     gene            complement(13942..14607)
                     /locus_tag="P5537_10110"
     CDS             complement(13942..14607)
                     /locus_tag="P5537_10110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78436.1"
                     /translation="MPKTTEQGNPQVPAAAEPPVSPTAIGEGLFSPNAGADGKMHVGI
                     SIDLATDGHPASLLIDNPGAEKGKDEGGGASMCLTRPLNIKFENLEAYLAEKVTLSAE
                     LRRLLVATELDCNALYYRDGGPTLVNIGLKSADKTGLIESLSGSKDLGKLFDITGVSL
                     RILNCPKACQTELEDYWKTVSALPSATPEEKASGDVSPPAESSAKDGEGKDAGPAEAP
                     AAT"
     gene            complement(14784..15107)
                     /locus_tag="P5537_10115"
     CDS             complement(14784..15107)
                     /locus_tag="P5537_10115"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78437.1"
                     /translation="MAAVGVVVEVIGDVVCGNPSGSSSATDRNGGCTAAAAAVTARAE
                     VETVSGGVVDSSSGGAPVAAGAAASARDAARSFRAGRDGDAGGGACAANKGSWSVFML
                     AFRVD"
     gene            15106..15672
                     /locus_tag="P5537_10120"
     CDS             15106..15672
                     /locus_tag="P5537_10120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015435973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78438.1"
                     /translation="MTPPSLPDAAPDEARALSSPPPPDVVAIRSDRLWQLDGWTARVI
                     KNEDDDGWAVEMLQDGEAEPALVGPWTMGRDKKNPKPFDQAAFNTLVKTASEVLQRHR
                     QQAHAMLHKRLTVFALDAQWDVRLDITPDEYEPYATLSAFDELGEEVAQVRVPPDFRL
                     GVASATAWISGGFARPAQASRGFEGWSE"
     gene            complement(15703..16074)
                     /locus_tag="P5537_10125"
     CDS             complement(15703..16074)
                     /locus_tag="P5537_10125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2784 domain-containing protein"
                     /protein_id="HRV78439.1"
                     /translation="MGYRLAADAVLLLHLGFIAFAVLGGLLALRWHLAPWLHLPAVAW
                     AAWIEASGGLCPLTPLENRLRVLAGQSGYPGGFIEHYLVPLIYPGELTRELQLVLAGF
                     VVLINLAVYAWVWRRRASRAR"
     gene            complement(16262..17329)
                     /gene="purM"
                     /locus_tag="P5537_10130"
     CDS             complement(16262..17329)
                     /gene="purM"
                     /locus_tag="P5537_10130"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HRV78440.1"
                     /translation="MADHHPEPLDPQPSLSYRDAGVDIEAGDALVERIKPFAKRTMRP
                     EVLGGIGGFGALFELSKKYKEPVLVSGTDGVGTKLKLAFQLNKHDTVGQDLVAMSVND
                     ILVQGAEPLFFLDYFACGKLDVDTAADVVQGIARGCELAGCALIGGETAEMPGMYPEG
                     EYDLAGFAVGVVEKADIIDGSRIVPGDVVLGLASSGAHSNGYSLIRKIVERAGTDMMA
                     PFHGRPFRDVVMEPTRIYVKPMLELMRAMPGVVKGMAHITGGGITENVPRILREELTA
                     RIDGDTWALPQMFRWLQFAGGVNQDEMYRVFNCGIGMVVIVSAAEAEAAEAKLTAAGE
                     TVYRIGVIDTRREGEAQTIID"
     gene            17471..>17981
                     /locus_tag="P5537_10135"
     CDS             17471..>17981
                     /locus_tag="P5537_10135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HRV78441.1"
                     /translation="MKPPRVDRLQTVAWTATGAALIALLWLLGPILTPFVVGAVFAYI
                     CDPAVNWMVARRVPRPLAVLLVICALGLLLIALALILVPMVYREGVLLVRRLPELVQM
                     FNLNIAPLLEARLGVDVRLDAAQFQQLVADNWTSAQELVPVVLGHLKTGGMAVLGFAA
                     NVLLIPLVMF"
BASE COUNT         2575 a         6778 c         6408 g         2220 t
ORIGIN      
        1 aacgctacga ggccgacgcc gcccgccacg gtcacccggt gcaagaggcg ctcggcgaac
       61 tgatccgcat cgccgacgaa cttgccggca tccgtcgcca cagcggcatg gagggtccga
      121 cggtcgtgac ctgaagacgg ccaccctccg actcccggcg ccagcccgtg ctcgaggcgc
      181 cgaccagcct ccggcacggt ccgcacggcg cggcacgcgt cgctcccgcg tgccgctccg
      241 ccgcatcgac tcctgtgcag gatcagcgtc cggggcggcg gggcgttggc cgcggcgccg
      301 gcgatcgtgc aaagtgcggg cggaagacga acagtgcgcc gccgttcgcg ttcgcggtcc
      361 ataggctgcc gtcggtgccg agcgcgagcg cgaggttttc ttcgggggcg ttcgcgaagc
      421 cctgtcccgc gaacagggcc cgcccgtcgg acgcgaagcc gtagagggtg ccgctgcacc
      481 agaagaagag gttgcctgcg ccatccatga ccggattcga gctggcgcac agtccggcgc
      541 cgaagcgcct gcccgcgtcg cccggcccga atccacgcac gttgagcgcg ccatcctgga
      601 cgaaccacac ccggccatcg ggtgccagca ccggctgcgt gctcgtcccg ccgctcgcct
      661 gccagcgtgg cgcccgccct gcgaaggccc acacccttcc cgtgccgtcc tcctcgtcgt
      721 agccggagaa gatccactcg ccgatgcgcc caccggccac cggcaggtga tgcctccagc
      781 cggccgcggc cgcggcgtca ccgaaggcga ggcgctcgac ctcggcgggc tcgtgcaggt
      841 cgaggaccac cgcgccctcg ccggtcggca ccgccaggcg ccggccgtcg atgctcagcg
      901 ccgcgctgcc cggcatgcgg ctccccgccg cctcgttgag cgcgaagaag agaaagggcc
      961 gcagccgcgc gtcgagaccg agcacaccat cgaagccatc gcccagcacg aggtagaggc
     1021 tgccgtcctc gccgacggtc ggcttggtga agggcgacag ccgcaccggc atctgcgcgg
     1081 cgacttcggg cagccggaag gtgtgacgca aggcgccgcc ggcctcgaga tcccaggcac
     1141 gcacggcgtc ctcggtgacc aggtagagca ggccctgcgg actgatgacc ggcgcccgct
     1201 gcaccacccc gccgccgatc tcgctcgacc acatcaggcc ccccttgccg tcgagcgcga
     1261 ccaggtagtt gagcctgccc cgcttctgca ccgcgatcac ctgatcccgc cacagcagcg
     1321 ggcgctcggc gagcaggccg ggactggcgt cctcgccgac ggcgggcagg gggagcgcct
     1381 gcagctcgaa gccacccggg ctgcgcgcgg gcttgaagtc gccacggccg ctgtgaccgg
     1441 cgtcgtgctg gggctgccgc cagcccgacg cggccgcggc cgcatcgggc gcgtactgga
     1501 tgaccaggcg cggcgcgtgc gaggcctggc gaaccccgtc ctccgccgac gcccggccgt
     1561 gcagcaggct gctcgcccgg gaggtggcgg tgtagagctc gagctcgagg cggcgagccg
     1621 gcgccgcggc cgcctcggcc acggcctcgc acagtcggcc gttgtccggg ttcagggaca
     1681 ccggccggtc gggtcgcagg tcgcgcagcg cggcaagcgg gcgcgtatca cccacgcgcc
     1741 ggaccgccag ctcgaccacg gcggcgaccg cctcgtgctc gcgcacgtag cgcacctcgc
     1801 tcgccaccac gcgcagcacg cagcgctgca tctgggccgc cgacaagccg gcgggcaggc
     1861 tggcgagatc gaaggccagc cgtaccccgt accccgtgag cagccagtag tactccgcct
     1921 ccgccgcctc cgcttccacc ttcgtccccg ccactccggc ggtcgccgta tcggcacccc
     1981 ctgcggtcgc ggcttcggcc gtcgatgcgt gcggggggtc gaacgcttcg aggagcgtcg
     2041 tcgagatcgg cgcgctcctc gcagccgaca ccttccccgg gctcgtcgca gccaccgcac
     2101 gctcggccgc cggcagcgag gcgggcacca gcgcgagcag tgccaggcac aggtgcagtg
     2161 atcgcagctt catccggtcc tccctttgcg caccccggcg gcgtggcgcc taggccggga
     2221 agtacagtcg cagcgcgcgg tccgccgcgc attcgttctc cgtggccagc agacggagga
     2281 ccagcgcgcc ggcgcgcagc gccagcacct ggaaatcctc gatcgccgcc gggaccaggc
     2341 cttgcaggtc ctcgcagggc agcaccgccc agcgcttcgc gggcgcgtcc accaggcgca
     2401 gcgcgatggc ctcgacccgc tcggcgtcgg cgcgagccgc atcggcgtgc cgactcgtcc
     2461 acgcgaagac gtgcaggctg cgcccatcgc tcgccagcgc ggcggcaagc acctgcccct
     2521 cgatcaggtc gccgagcagg aagctgcgct cccagcgcag gccatcgaag gaccacaggt
     2581 cgaagcactc gcgccgctcc tcgtcctcct ccctgagcgg ctcggagccc tccccgaccg
     2641 gttcggagcc cacctcgccg gcgctcgccg aacctgcgcg gccgaacagc cacagccgcc
     2701 catcatggag caccggctgc gcagcgccgc acggacgctc gcgcggcccc cccgccgcct
     2761 gcacttgcca gtccagggtc ggcaccgcgg cctggtcgac aggcttcccc tcctcggcag
     2821 gcgtccacac gacggcgccc tcggcaggct cctgtgtcgc cgcccaggcg tcgtcgagcg
     2881 acgcaccggc ggagtcgatg ccgccgaaca cccacaggcg atcctcgaac accgccacgc
     2941 catgcgcccg ccgggcgcac cagggcgcct cgccatgatc ccgccagcgc ggttcgcggg
     3001 caccgacgtc gaggctccac accttgctgc cgcagcgtcc ccgcgcggcg gacggagcac
     3061 cgagcaacca caggcggccg cggaacaaca cccctggcag gcgctcgcag ccatgcggga
     3121 aggccgggaa cgggcctgcc ccctcgactg ccatttcggc cgccccctcg gcgcccccct
     3181 tgcctgcccc cgccgcgccc accagctccc agggccccag cgcatggcgc gcccggcaaa
     3241 gcagcacgca cgacccgcca acgccaggca atgcgacgct cgcgtacagc atgccgccgg
     3301 ccacgccgaa caggcgtagc ggcaaggctt cgccgctcgt ggccgcggtg gcgggcacgc
     3361 ccagcctgcg gccctcccgc gtcgccagca tgcagggcca gcgctgccag cccggccgca
     3421 aggcgcgcac gcgcaagccc gcctcgtgac gttgccccgc ctcgtcccag ccgcgcagcg
     3481 cgaactcggc atcgccaacc ccagccacga cgcgccggtg gcccgcgtcg gcgaggccct
     3541 cggcgatgca caggccgtcc cgcagcaagc tcaggtcgga caggccgcac gtgcgccagc
     3601 gcagctcgac gacatcgccg ggaagattca tcgcggccgc ttccgggacg caggcgaagc
     3661 cgaggacgcc ggcagccgac gcacgcttgg cgagttgcag cgggatcacc gccgcggccg
     3721 ccgcatcgcc gcgcgcctgc agcctcagct cgagcgccgc gaggccgggg cgcgcgtcgg
     3781 aggccgcgcc cgaaaacacc acttcgaggg catcgcccgg ctgcagcagg gcgtcgccgc
     3841 ggcgcagcag ccacaactcg cagccctccg gccacgctgg cggcagcctc cactgcgcca
     3901 cccagcccgc cgaagcctgg cagctccagc gccgcagttg cgccgcgtcc cgcaccaggt
     3961 cgccctcccc gccgccgaca ccgcaacgca ggacgagcgc cggccagcgc gcacacgcga
     4021 gcccctgccc gccacggtag tcgatgcgca gcgtcagccg gttggccgcg gagcgcgcgc
     4081 cgacgacgaa gtcgcccatg caggcgatgc gtgcaacgag gcccatggca gcgtccgtca
     4141 tgcaggcctc cgcagtcgca actccacctc ggcgatgcgg cacgccggcg gcgagtcgcg
     4201 atcggaggtg gcaagccaac gccatgcgcg caggcggtag cggccggcca gcggctgtgc
     4261 cagcgcccag gtcgacggca agggcgctgc cgcggtgcac agcagcacgc gcccatccgg
     4321 tccgctcagt tcgatggcgt cggcaccgct caccgtccac gcgagcgtgg cgggcagctg
     4381 cggcggcagc tcgaagcccg ccaccgcatc ctgcgcggcg cccgcagacg gtgcggcgac
     4441 cgcggcgtcg accacgccga agccgtcgat cgcgagcgcg accgcttcga gccgcagcca
     4501 gccctcggcg agggcgaggt cgggcgggaa ggtgacgctg ccgctcgccg cggtgtcgat
     4561 gacctcgcgc tccgcgcgca cgcccacgcg cgggtgatgg ttccacgccc actggccgta
     4621 gaggtccgag ggccggggca ggcgcagctc gctgcacgcc cccagcaccg gaccggtgaa
     4681 gaacatcagc gaacgcgccc gcacccgctc gccggcgccg ggcggccgga agtgcgcgcg
     4741 cgggagcacc gcgctggtca ccgtgaagcc gcgctccgga tccatcagga ggatgagctc
     4801 gagcgggcgc tcgatgctga gcacgggctc gctgcgctcg cgcagctcgg gccggccctc
     4861 gccggtgcgc agcccccagg ccgggtggaa acgtcccggt tcgtcggcga ggaagaagcc
     4921 tgcgagcccg tcctcgccgc tgccgccgaa gtcgcccagg cgcagcggaa acgcgatcgc
     4981 ctcgacgccg ccgcagcggc cttcaccctg ggcgctcgcc gggtcgtggg cgggcaagcc
     5041 atcgagctcg agtcgcaggc gcgcgcgcac cagcgccagc ggccgtccga cgagcaggcc
     5101 gacggcggga tcgtcggcat cgggcgcgag ctcgcccgcc gcctgctgca aggcgtcgag
     5161 caggtcggcg aggcgtgccc cgctcgcccc ctgccagcgc agcagctcgc gcacgagctc
     5221 gcggacgagc ggatcggcgc cgcggtcggc cagcgggtcg gccggatcga acgcggtctc
     5281 gcccggcgca tccgccgccg tcgaggcgtg gggaccgagc gtcgccaccc agcggaaacc
     5341 gtcgatcggg cgggtacgtc cgccgacgcc gtgcgcatcc gccttgccgc gcatcgcctg
     5401 cagcgccccg aggaggttgc cggcggcgtc gagcagcgcc agggtgccgc cgatccgatc
     5461 gggcaggatc caggcgcagg cttcgccctc gccgggctcc gcggcggcat cctcctgcac
     5521 ccgcgctgcc tgcccagcag ctccgtccgg gttcctcccc ccaccgcgcc agcgcgcggg
     5581 cgccggccag tccaccacca gacgggcggc ctgcaccagg cgcggctcga acagcgcggc
     5641 cccgcctggc ccgcgcaggc gcggcggcag caccaccgga agcgcaccgc cgccctcggg
     5701 ctgcagctcc atgaagcggc cgaacgcgtc gatgacgcgc aggcgctcga tgcgcagcag
     5761 gccggcgcgc agcggcagca ggcgcgcgtc gcgcagcggc gacagcccgt cggcggcctc
     5821 gagctgcgcg gcatgcgggg cgggacgcag cggccccgca tgcccctcgg cctcgagcgg
     5881 gggaagttcg gggcgggcgc agcgggcgag caggccatcc atcaggccgt cgaggctctg
     5941 gccgaggacg tcgatcgcgg cgacctccac gccagcctcg cacaggcgcc gctgcagcga
     6001 gtcggccacg ccgggcgtca tcagcgaggt gccggtgaac acgtgctcgc gcccggggac
     6061 cgcctcggcg ctgcgctcgt agccatcgcc gtgcgcaccg agccgccagc ccgcgagcgc
     6121 cgcagcgccc tccccggccc gggcgagctc gctccacgac acccgccatt gcagcagcag
     6181 cggcagccag gggttgccgc accagcgcgt gcaggcgatc gccgcgggaa cggagtccgc
     6241 gctgccaggg gcaccactcc cggagccact tccggaacca ctctcggagc cgtcggcggg
     6301 cgtgcccacg gacgcgggcg gcgcgcttgc gcggccggtc tcggtcgcgt ccgcaagggc
     6361 aaccgcgacc gcgtcgtccg cacgcgcgat ttcgatcgcc tcgcgcagca gccgcgccgc
     6421 aggcgcaggg atgccgcggc gctgcagctc ggcgtccgcc agcgcgccga tcgtgggctc
     6481 atccttggcg gcggcagcct ccccctgagc caggcaggcg ctggtccggc agtgcagccg
     6541 gccatcggca cgatggcgac cgtccttgcc atgccgtccg gggtcggcga aggccggccc
     6601 ggcgagcagc aggaccgggt cgcgcgggcg atggaagcgc tcgccgtcga cccttcgcag
     6661 ctcgtagccg gggagcaggc gttcgaccag cgcacgcacg cgctcgagcg gacgcccgcg
     6721 cggtatgccc tgtgcgtcga cccgcgcggc gaggcgctcg cgttgcgcgg cgatcttcgc
     6781 cagcagtgcg gactcctcgg cgcgccagcg ctcgatggcc tcggggtcgc agtcgaagct
     6841 cgccaggccg cgctggtacc aggcgaggta gagcgcctgc ccgaggctgt ccagctcgcg
     6901 cgcgagggcg tcggcctcgc gctgctgtcg ctccagggcg gcgagcgcgc gccgcacgat
     6961 gccggggatg gccttgcgcg ccgggcgccc ggcgcgcagc ggggcgggct cgcgctcgac
     7021 gatctcccaa ccggaggcgc gcgacagcgg ctggaagcgg cgcgcatgca gctcgtgggc
     7081 gagatgttcg gcgccgcccg ggcgctcgag caggggatcc aggtcgtgct gcaaggcctc
     7141 gaagtacgcg gcgtgctgcg ccggcacgcc gggctgggcg ccgagcagcg ccgccatggc
     7201 ctcggcgccg tgctcgccga gggcggcgcg gaagggagcg ccgcgcggcg gaccgccata
     7261 cgcggcggcc gcgccgcgcc agcgtagccc ggcgaggagg ccatggcaca ggatgcgccc
     7321 cggcagatgg tgccaggccg tgtcgagctc ggccttgcgc gcctgcgcct ggcgccgcgc
     7381 ctcgacgtac tccctcgcga gccagcgtac cgcgtcgcgc ggcacggcgc cgcggcgccg
     7441 ctgcgcaacg cggcgtgcgt gcgcgctcgc ctgctgcgcc cgctcctccg cccggtggcg
     7501 ctcgtcctgc ttggccagga gctcgtcgag cccgggatac acccacgcgc agccctcgaa
     7561 caagtccttc caggcattcc agtcgcgcgc cgcgagcgcc ttgtgcaggc aggcggcgag
     7621 cggatcgtcg tccttggggg cggagtacca gccgagcacg aggtagtgca gctcggcctc
     7681 ttgcagggcg cacacctcct cgtcgtggaa gccgagcacc ccgcggccgt gcgggaagct
     7741 cgccgcgaac accggatcgc cgtagccgag ggcggtgatg ccgggctggc gcgcggggtg
     7801 agactcggac caggcctcga gcggcacgca gcgccccagg tgcacgatca gttcgtcccg
     7861 cgcgagcggc gcggaagcgt cgacgacccg gcgcggccac gcacgcccct cgcgcacgcc
     7921 ggtcagggtg tcgctctcga ccacccagcc ccggcacgcc gcacccgccg ccgcgaaacg
     7981 cagtaccagc cagcggttgg ggatcgccgg catgcgcgca ccggcgtcct cgcccgcggc
     8041 cgactccggc gcgtgcgtga ggccgtcggg cagcgaccag tgcaggtaca cgccgggcgc
     8101 gagcgcccgc ggcgtctcct ggaaaggctc gcggccgagc aggctgccca ggcacggccc
     8161 cccctcggcg agcgcggaga aatccaccga gagatcgatc gccgcacttg ccgcgccgac
     8221 cgcgagcgcc tcgacgttca tcggcacgag caggcaggga cgggagaaat cagccgacac
     8281 cggcacctcc gcgcgcgatc ctgaagcgga aggccccggc ggcctcgatc atctgcatcg
     8341 cgaagtcccc gggcccgaag ggcgcggcga cgcccccgtc gggcacggcg ccgccagcgc
     8401 caatggatgc gctcgccgcg ccgcctggct cgagcgccgc acgcagcgcc cgggcgagcg
     8461 cgtcgatgtc gatcacccca ggggccgcgc aggcgttcat atccccctgc gactcgccgc
     8521 gcatcggcac ctcgataagg gccccggacg tctgcgcggc acccgtctgc gcgcagcgca
     8581 gggtccgcgt gaagccggcg ccatcggcct tcgggctgag cccgaagtgc aggccctcgc
     8641 gcggctggcg gatctcgacc atgtccggca tgccattgaa gagcacgagc atgacgtcgt
     8701 cggccagctg ctcgatgcgt agcgcaggca gcttggcgtc gccaagccag ccctcgatct
     8761 ccagcccacg ccagccttcg accaccgccg agcgcagcag gaagccgccg agcggccagt
     8821 ccaggccggc gggggggttt gccgaggcct tttccgagtc ttcttccgag tcctcttcct
     8881 gggtcttttc cggggccttt ttcgagtccg tcttgcgccc ctcgcattcg gcgcgcaggc
     8941 gcgcgcgctc gcccgccgcg gcgcgccccg cctcccccgc ggcgctcgcc tccaccggca
     9001 ggtcacgctc cgcggcgggc tcggccacgt cgggcgacag gcagaagcgc atcacccggt
     9061 tgacgaggag atcgccgcag tccgcgttgc cgacgctgca cgccccttgc accagcgcct
     9121 ggatccagtt cgggtcgagg aagaagaggc gcagggtctc gggcggcagc atgtcctcgt
     9181 cgggcaccag gttgtgcagc ggcacgccgt agagcagcac cagccggccc agccaggcgc
     9241 tggcctcggc gagcatggtc tggagctcgg tcgcccgcag caccggcgca gccgttggcg
     9301 ccgaggctgc gggcgcgatc ggggcggtct ccgggccgag gccggcgcgc acggccccga
     9361 cgccggcctc gatcgcctcc gcgcaggcca gcgcgagcgt ctcgcgcagc cgcccgggcc
     9421 gcccggcctc gtcggattcg tggcgcgcgc cagcgcgctg cgcgaggccg gccacggtgg
     9481 gggcgtggcg cagctcggcg aggcgccgcc gcagccccag gcgcgcgcgt tcgagcgcga
     9541 gcacgaagcc gcggttctgc agcgcgagca ggcgcccgag ctgccacgcg ccggcatagg
     9601 tggtgtcgaa catgccgcac tcggggtcgt agcgcaggag ctcgtcgctg cagcgcacca
     9661 ggcgctggac ctggcgcggc tgcgagtatt ccaggggcac gagcggaccg cgataccagg
     9721 acacggtgtg ttcgccgtga cgcagccgat gatcgaacgc cgcgtagccg cgggcgagcg
     9781 cgccacgcac gagcgccgcc ggcgtcggcg cctctccggc cgggcgtacc ggagccgctt
     9841 ccgccgcatg ggccggctcg gccggaggca ggggcaggtg gagccaggcg tcgggctcgg
     9901 cggcggccct ctggtcgccg gctgctgcgt tcccggcctc ctcgcccgcg gttcgtgcgc
     9961 gctcgaaggc gcccgcgtcg agcccgcgca tcctggcctt gaagtcgccc ctgccgagac
    10021 actcgaatcg ccagctcgcg agcaccgcga ggcgcacgct gtcgtagccc tcgaggccgc
    10081 tggcgtcggt gagcacgtcc gcgaagccct ccagcgagac caggaaggcg tgatgcgccc
    10141 gccccgggct cggcatgcgg ttgccgatcg ccacggcgta ccagccctgg tcgtggccgc
    10201 ggaagatctc cttgtcgccg gtgtcgatca ggcgggcatg ggcgagccag ggcaggtccg
    10261 caatccgggg ggcgatcgcg gcgaacagct tcgccggcat gtcgagcgcc tggcagcgct
    10321 cgccgccatg gcgggccagc aggcgcgcgc gctcgtcgcc ctcctggccg agcgcgggga
    10381 cccgcagcct gtcgagcctt ttgccctgag ggtcgaacgc gaagagcagg ctgtcctccc
    10441 gggcgtccgc gccaccgcac accggcagcg gacgcggcgg gacacagggt ggcagcctgc
    10501 tctcaccctg ctccacaccg gcgagcagtt cgtcctcgtc gagcagcagc aaggcgagcc
    10561 agggccgcgg cggttctgcc tgcgagtgcc cgtcgagcgt gcgctcccag ggcagcgtgc
    10621 ggcgggtgaa gaccacgtgg ggcagcgcgt cggcgaaggc gccggccgcc cctggcggcg
    10681 gataggtggc gtggatttcc gccggctcga ggcggaaccg cggcccatcg acgctgaaca
    10741 ccagctcgga cgcgtaaggc ttcgagtgca tcggaaaggg gccgaagggc gcagcgcgca
    10801 cctcctgctt catgcgcagg cggtagtcgc ccgccgcgag cgcgggcagg caggcgtcgg
    10861 cgaagcggat ctgcccgggt tcgacacttg gcgaagacac agcggcggac tctcccatat
    10921 cgacttgatc agatctcggc gaacatccgc ggtacgtcct gtccgacccg cgccatcagg
    10981 ggctcgacat cgaggacgtg tgcgggcgcg gcggcgagga tgggcagctc ggcgtccgcg
    11041 ctcagcctgc gcacgcggcg gccggcgttg aggcagtcca cgatcgccct gcggcgctcg
    11101 accacggcgt ccttcatgat cgtgtcgccc agcccgtgcc ggctcccggg caaggccgtc
    11161 gcgggccgaa gcgcaccgac cgcgcggcag cgatactcga accgatcgta cgcgaaggcc
    11221 tccagctcga gcgccggccc gatcctcgta tccggatcga cccgaccgcg caactcgatg
    11281 cccaccggcg caccgtcgat gagctgcctg cccgacagga tggccgggcc gagccggaac
    11341 ggactccaca gcgcgcaggg gacgctggcg gtcaggggca ggacgtcgag ctcggcctgc
    11401 gcgtcggtgc gcacggcgcc gtccgcgtcg agcgcctcca gcgtgacccg gatctcggac
    11461 tggaagcgcc ccaggcccat cggctgcacg ccgagctgcg gccagctccc ggcctcgcgc
    11521 gggggcacct ccgcgtcccc gaagaacagc gcggtcgcgg gcacgctgct ctggcagcgc
    11581 aggtacaggc gatgggcctg cagcaccggg cgctgcggca cgccgcccgg gggggcggcg
    11641 ggcgtgtcga gcaggccatc gacgaccgag atgcgggtga cgtcggggtt gccgaggaag
    11701 ctgtgcgcga aggagcgctc ggggtcgtcg gactcccaga ccatcggcgg cggcagggtc
    11761 ctcggcggcc cgaagccgac ggtgaagctg accacgtaga gcgagacgcg cacgctgccg
    11821 gcgagcggcg ggccgtacag cgcgatcgcc gcgccgagct cgatcgacag gcggatgcgc
    11881 acgaaccaga tcttgatgtt cagctgcacg cccagggaga ccgcgaccga ggcctcgtag
    11941 tggagcggct tccactgcat caggaagtct gcgcgcgcga ccagccaggc gcggatgccg
    12001 cccgacgcgt agacgatcga caggctgccg ccggccatga tcgcggcggg acagagggcg
    12061 aaatagcact gcccgctgat cgtgacctgg ccgatctggc agttgaacgc cacccgctcc
    12121 gggcgcgggt aatgcgccgg aacctggaag gcgggatggt agccaccgac cgagacgacg
    12181 aagtcgcccg catgcgggcc tgcgtaccag gcgaagaagg cgaagccgcc actcaggcgg
    12241 aaatcgcgcc gcagcacgaa ggagttctcg gtgagccggc cctcgaccgc gaccaggccg
    12301 tcgtcgggcg cgatcaccac gcgcagctcc atctccacgc aggccatcgc agcgtcgccg
    12361 cccgccttgc gcggcagctc caggcgcgac aggccgagca cgccgatctc cagccggttg
    12421 ccgaaggcga ccgagagcat cgccaccgac tcgacgatgc cgaaggaggt gaagcgtacg
    12481 ccgccggcga tccacatgct gtcgtgctcg ggggcgagcc aggtgtccac caatgcgccg
    12541 atgcgacgcg ggtcggcgtc cttgccgaga aaatccggct cggccgccgc gcgcagcaag
    12601 gggaagctgt gcacctgccc gatcggcggc agggtgaggc ggcggtggat gccgatgccc
    12661 aggcacagtc cggtgacgaa gaagaagggc gggccgccga tctccttgtg caaggcggcg
    12721 aaggcgaaga aggagtgcgc gccctcgatg cgctcgtagg agccgatcgc gctgacggtg
    12781 agcaccggcg tgctcacgcg caggctgccg tccaggcgca gggtctcgcc cgcggcccgc
    12841 gtcagcccgc cgctgatcgc gatcgccccg gtctcgagcc cgagcatcgc accctcgagc
    12901 cggacgccga ggccctccat cgcggcccgc ggccccttca gcagcgccgc gagcggacag
    12961 tccaccccga agccgaccag ctcgaaggac aggccgccga tgcgcaaccc ggcatcgagc
    13021 gcgatggcga gccgggagga ctcgtagacc aggccgacgc ggcggaatgt cagcggcccg
    13081 atgcgcttgt cgacgcgctt ccagaacgcc ttgccgcggg tcggcagggg cgcttcgggc
    13141 gggggaggcg cggggggcgt ggcggagggc tcgggccttg cctctgcgtc acccgcctgc
    13201 gcgtcgaggg tgtcgccgcc gtcgccgggc tcgctgctgg cgcgcccgag gccttcgagc
    13261 agatcgacgc caccgatcag cacccgcccg gagagattca gccccgcgtg caggctgcga
    13321 gccggtcctg cgggctcgac gaggggcgcg aaggcgcccg gcgcggtcgg cggctcgagg
    13381 tgcaggtcgc tgcagtcccg gctcgcatgg aaaacgccga ggcgctcgac caccactcca
    13441 ccgatcagct cggagaggcc cttgtcgccg atcggcctgg gctcgagctc gagctcgaag
    13501 ccggccacca ggccgccctc atcctccgcg cgcccggggg cggggagcag cttcgcgacc
    13561 acgatccggg tgcgtccgga ccccgcaccc agcgtggtgc tcagcgtcac gctgggcgtt
    13621 ccggcgctgc gataggcgag ctcgacggct tcgaaatgga tctccgccaa ggcaccccca
    13681 cccagggcgt caagcgccgc gcgcgggccg gcgaaggcgt ggccgagcgc gatgagcagc
    13741 ccgccgaggg tgtcggtcgc ctcgccctgc aaggtccccg cgaggctcgt cagcccgcca
    13801 tcggcgagcg ccccgcgcag cacgagcgga cgaccgccaa ccctgaggtc gactccgagc
    13861 tcgaccgtcg tcggcgtggc cggcctggaa tcccccggcg tgctcacccg gcggctccgc
    13921 ggcaaggccg ctggaccgac ctcatgtggc ggcgggcgct tcggcaggac ccgcgtcctt
    13981 cccttccccg tccttggcgg acgactcggc cggcggactc acatccccgg acgccttctc
    14041 ttcaggggta gcggatggca atgcggaaac ggtcttccag tagtcttcca gttctgtctg
    14101 gcaggccttc gggcagttca ggatccgcag cgacacgccc gtgatgtcga acagcttccc
    14161 caagtccttg ctgccgctca gcgactcgat gagcccggtc ttgtctgcgg acttcaggcc
    14221 gatgttcacg agcgtggggc cgccgtcccg gtaatagagg gcattacagt cgagttctgt
    14281 cgcaaccaac agtcgcctca actccgcgct tagcgtcacc ttctccgcga gataggcctc
    14341 gagattctca aacttgatgt tcagaggacg cgtgagacac atcgacgcgc cgcccccctc
    14401 gtccttaccc ttttcggcgc cgggattgtc gatgagcagg ctggcgggat ggccatctgt
    14461 cgcgaggtcg atgctgatac cgacatgcat cttcccatct gcgccggcat tcggcgagaa
    14521 caagccttca ccgatggcag tcggagaaac ggggggttcg gcagcggcgg ggacttgcgg
    14581 attgccttgc tccgtggtct tgggcatgac gagaactcct gacggaatgt gggcgtggaa
    14641 agcgggattt gcgggcggcg ataattccgt gcggaaggcc gcagctttca ttcaacatag
    14701 acgccccagc ccggggcttc cagtccggct ttcaccttca ccgcctcgca gtgcttgccc
    14761 gtacccgaag actgtataaa atatcagtcc acacggaagg caagcatgaa caccgaccag
    14821 ctccccttgt ttgcagcgca ggcaccgccg ccggcgtccc catcgcgccc ggcgcgaaag
    14881 ctacgcgcgg catcgcgcgc cgacgcggcc gcgccggcgg ccaccggtgc cccgccgctc
    14941 gacgaatcca cgacacctcc cgacaccgtc tccacctccg cccgtgccgt cacggctgcg
    15001 gccgcggccg tgcagccgcc gttcctgtcc gtcgcgctcg agctgccgct cgggttgcca
    15061 cagaccacat ccccgatcac ctccactacc acgcccaccg ccgccatgac gcccccctcc
    15121 ctccccgacg ccgccccgga cgaagcccgg gccctgtcct ccccgccccc gcccgacgtg
    15181 gtcgccatcc gcagcgaccg cctgtggcag ctcgacggct ggaccgcgcg cgtgatcaag
    15241 aacgaggatg acgacggctg ggcggtcgag atgctgcagg acggcgaggc cgagcccgcg
    15301 ctggtgggcc catggaccat ggggcgcgac aagaagaacc ccaagccttt cgaccaggcc
    15361 gccttcaaca ccctggtgaa gaccgccagc gaggtcctgc agcgccaccg ccagcaggcg
    15421 cacgcgatgc tgcacaagcg cctcacggtg ttcgcgctcg acgcacagtg ggacgtccgc
    15481 ctcgacatca cccccgacga gtacgagccc tacgccacgc tgagcgcctt cgacgagctc
    15541 ggcgaagagg tcgcgcaggt gcgcgtgccg cccgacttcc gcctcggcgt agcgagcgcg
    15601 accgcgtgga tcagcggcgg cttcgcgcgt ccggcgcagg cctcgcgcgg cttcgagggc
    15661 tggagcgaat gatctggccg gccccggccg cagccgcgcg cgtcaccgcg cccggctggc
    15721 ccggcgacgc cacacccagg cgtacaccgc caggttgatg agcacgacga agccggcgag
    15781 caccagctgc agctcgcggg tgagctcgcc gggatagatc aggggaacaa ggtagtgctc
    15841 gatgaagccg cccgggtagc cggactggcc ggccagcacg cgcaggcggt tctcgagcgg
    15901 agtgagcgga cacaagccgc cgctcgcttc gatccacgcg gcccaggcga ccgcgggtag
    15961 atgcagccag ggggcaaggt gccagcgcag cgcgagcagc ccgcccagca cggcgaaggc
    16021 gatgaagccc aggtgaagca gcagcaccgc gtcggcggcg aggcggtagc ccatggcgcg
    16081 gagcgctcct ggccggcggg atggaacggt cccccggggg tgcgccgagg gatacgcgac
    16141 agagatacgc gaaagggacg cgcggaagcg gacgcgaacg attccgcaaa tacggcgcag
    16201 agggatggcc cgcaaggatg gcgcgcgcag ggtcgcccct ctgcgcgccg gcgtgcatcg
    16261 ctcagtcgat gatggtctgc gcctcgccct cgcggcgggt gtcgatgacg ccgatgcgat
    16321 acacggtctc gcccgcggca gtcagcttcg cctcggcggc ctcggcctcg gccgccgaca
    16381 cgatcaccac catgccgatg ccgcagttga agacgcggta catctcgtcc tggttcaccc
    16441 cgccggcgaa ctgcagccag cggaacatct gcggcagcgc ccaggtgtcg ccgtcgatgc
    16501 gcgcggtcag ctcctcgcgc aggatgcgcg gcacgttctc ggtgatgcca ccgccggtga
    16561 tgtgggccat gcccttgacc acgccgggca tcgcgcgcat gagctcgagc atgggcttga
    16621 cgtagatgcg ggtgggctcc atgaccacgt cgcggaaggg gcggccgtgg aagggcgcca
    16681 tcatgtcggt gccggcgcgc tcgacgatct tgcggatcag cgagtagccg ttggagtgcg
    16741 cgccgctcga ggccaggccg agcaccacgt cgcccggaac gatcctgctg ccgtcgatga
    16801 tgtcggcctt ctcgaccacg ccgaccgcga agccggcgag gtcgtattcg ccctcggggt
    16861 acatgccggg catctcggcg gtctcgccgc cgatgagcgc gcagccggcg agctcgcagc
    16921 cgcgggcgat gccctggacc acgtcggcgg cggtgtcgac gtcgagcttg ccgcaggcga
    16981 agtagtcgag gaagaacagc ggctcggcgc cctgcaccag gatgtcgttc acgctcatcg
    17041 ccaccaggtc ctggccgacg gtgtcgtgct tgttgagctg gaaagcgagc ttgagtttgg
    17101 tgccgacgcc gtcggtgccg gacaccagca ccggctcctt gtacttcttc gacagctcga
    17161 agagcgcgcc gaagccgccg atgccgccca gcacctcggg gcgcatggtg cgcttggcga
    17221 agggcttgat gcgctcgacg agggcgtcgc ccgcttcgat gtccacgccg gcgtcgcggt
    17281 aggaaaggga gggctgggga tccagcggtt cggggtgatg gtcggccaag atcgttcctt
    17341 cgagctcgca ggctgccggg cctcgccgca tgcccggtgg aaccgagctt gaggccgcaa
    17401 cgccaagtgg ctacatttac gtgttctgcg ggcggctctc gcccgcgcca agcccgcgat
    17461 tttactttaa atgaagcctc cccgcgtcga tcgcctgcaa accgtcgcct ggaccgcgac
    17521 cggcgcggcc ctgatcgccc tgctctggct gctcggcccc atcctcaccc ccttcgtggt
    17581 gggcgcggtg ttcgcctaca tctgcgatcc ggcggtcaac tggatggtcg cgcgccgcgt
    17641 gccgcggccg ctcgcggtgc tgctggtgat ctgcgcgctc ggcctgctgc tgatcgcgct
    17701 cgcgctgatc ctcgtgccga tggtgtatcg cgagggggtt ttgctggtgc gccgcctgcc
    17761 cgagctggtg cagatgttca acctcaacat cgccccgctg ctcgaggccc ggctcggcgt
    17821 ggacgtccgc ctcgacgctg cgcagttcca gcagctcgtc gccgacaact ggacgagcgc
    17881 gcaggagctg gtgccggtgg tgctcggaca cctgaagacc ggcgggatgg cggtgctggg
    17941 cttcgccgcc aacgtcctgc tcatcccgct ggtgatgttc t
//
LOCUS       DAOTIN010000059        17740 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_3829_length_17740_cov_10.015889, whole genome shotgun
            sequence.
ACCESSION   DAOTIN010000059 DAOTIN010000000
VERSION     DAOTIN010000059.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 17740)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 17740)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17740
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3829_length_17740_cov_10.015889"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1066)
                     /locus_tag="P5537_10140"
     CDS             complement(<1..1066)
                     /locus_tag="P5537_10140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011764882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VC_2705 family sodium/solute symporter"
                     /protein_id="HRV78442.1"
                     /translation="MDLQTITYLVVGASFALYIGIAIWARAGSTSEFYAAGGSVHPIT
                     NGMATAADWMSAASFISMAGLIANMGYGGGLFLMGWTGGYVLLAMLLAPYLRKFGKFT
                     VPQFIGDRFYSKTASTVAVVCLLTASLTYIIGQMTGVGVAFSRFLGVSSETGIYLGMA
                     IVFMYAVFGGMKGITYTQVAQYIVLISAYLVPAIFISLQLTGNPLPQLGLGSDISGTD
                     TTLLAKLDLVVKDLGFDQYTTSMPGSMLNMFMYTLSLMIGTAGLPHVIMRFFTVPTVK
                     DARSSAGWALVFIALLYTTAPAVAAMAKLNLHATVNKAVGLETDAGGRMVVNAEKITA
                     NADLYATESSLQYEQRPEWMK"
     gene            complement(1080..1337)
                     /locus_tag="P5537_10145"
     CDS             complement(1080..1337)
                     /locus_tag="P5537_10145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4212 domain-containing protein"
                     /protein_id="HRV78443.1"
                     /translation="MENNSASGYWKATLGLLTKILIIWFVVSFGAGILFAPALNSISL
                     GGYPLGFWFAHQGSIYIFIALIFYYAKKMGDIDRQFDVHEE"
     gene            complement(1566..2810)
                     /gene="icd"
                     /locus_tag="P5537_10150"
     CDS             complement(1566..2810)
                     /gene="icd"
                     /locus_tag="P5537_10150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008953390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004450 - isocitrate dehydrogenase (NADP+)
                     activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent isocitrate dehydrogenase"
                     /protein_id="HRV78444.1"
                     /translation="MSESKIKVPAGGQKIVPGQAVPDNPIIPFIEGDGIGVDITPVMI
                     KVIDAAVDKAYGGRKKIHWMEVYAGEKSTRIYGPDEWLPKETFDALKTYSVSIKGPMT
                     TPVGGGIRSLNVALRQELDLYQCVRPVRYFKGVPSPLKQPELTDMVIFRENTEDIYAG
                     IEWQALSEGAKKVIDFLQGEMGVRKIRFPATSGIGIKPVSIEGTTRIVRAAIRYAIDN
                     DRKSVTLVHKGNIMKFTEGLFRDTGYKVAQEEFGAQPIDGGPWCKFKNPNTGREIVVK
                     DAIADAFLQQILLRPAEYDVIATLNLNGDYVSDALAAQVGGIGIAPGANISDQYACFE
                     ATHGTAPKYAGLDKVNPGSLILSAEMMLRHLGWKEAADLVIKGMEAAIADKQVTYDFA
                     RLMEGANEVSCSEFGDAMIARM"
     gene            3099..4862
                     /gene="aceK"
                     /locus_tag="P5537_10155"
     CDS             3099..4862
                     /gene="aceK"
                     /locus_tag="P5537_10155"
                     /EC_number="2.7.11.5"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008772 - [isocitrate dehydrogenase
                     (NADP+)] kinase activity [Evidence IEA];
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional isocitrate dehydrogenase
                     kinase/phosphatase"
                     /protein_id="HRV78445.1"
                     /translation="MDVQSGESPVAQAIAQALVEGFNKHYRIFRETSRRAKELYEAAQ
                     WQKQLDAVRERVQFYDDRVDETVQRLHDEFDADSLDDSTWLQVKLQFIGMLINHRQPE
                     LAETFFNSVTTKILHRSYFNNDYLFARPAISTEYIESYPPVYSSYYPRDRGLRATIRR
                     IVEDFDWQRSFEDLDRDVDFVMRAAQAHLGDWPPMEVNCQIQVLYSAFYRNKTAYIIG
                     KTVNGYQEYPFAIAVRHNERGLLYLDTLILDPWRISVLFSLSRAYFLVDMEVPSGYVQ
                     FLRSIMPNKPRSELYTMLGLGKQGKTMFFRDLVSHLRHSNDQFIVAPGIRGLVMLVFT
                     LPSFPYVFKIIKDVFGASKNMDRATVKRKYLMVKHVDRVGRMADTLEFSYAALPLARF
                     HPELLEELRTLAPSSFEIDGDKVIIKHLYIERRMTPLNLHLEKASDAELEEAVKEYGN
                     AIRELAIANIFPGDMLWKNFGVTRYGRVVFYDYDEIEYMTDMNFRRIPPAPYEEMEMS
                     GEPWYSAGPMDVFPEEFATFLLGVPRVRKAFLRHHRDLLAPKFWQDAQQRIRDGYVED
                     FFPYPVELRFCKLFPPAAGAA"
     gene            complement(4880..5203)
                     /gene="soxZ"
                     /locus_tag="P5537_10160"
     CDS             complement(4880..5203)
                     /gene="soxZ"
                     /locus_tag="P5537_10160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate oxidation carrier complex protein
                     SoxZ"
                     /protein_id="HRV78446.1"
                     /translation="MANPMRIRADVRDGVTDVRMQVPHPMESGQRKDDKGAVIPAHFI
                     TQLEVRHGERVVFSAEFGPSVSANPFLRFRFKGAAAGDRLVASWVDSRGETRSDQVQI
                     GGAAA"
     gene            complement(5232..5696)
                     /gene="soxY"
                     /locus_tag="P5537_10165"
     CDS             complement(5232..5696)
                     /gene="soxY"
                     /locus_tag="P5537_10165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate oxidation carrier protein SoxY"
                     /protein_id="HRV78447.1"
                     /translation="MDRKRRQVLRAAGGLGVLGMLAQAGLISPAQAQAAAARPGFDAR
                     ELNAALAALGAQDATASTELSLTAPDIAEVANAVSVEVRSRLPGTDRIAILVEKNPFP
                     LAAVFSIPEGTQPEVITRLKMAQSADVVALVRAGGRFHVARKAVIVTISGCG"
     gene            5865..6158
                     /locus_tag="P5537_10170"
     CDS             5865..6158
                     /locus_tag="P5537_10170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome C"
                     /protein_id="HRV78448.1"
                     /translation="MTNRLLASAFVLACAVAPAQAADPHLARNLAATCANCHGTGGRS
                     VYEPLVGRPREKLLSMLADFRSGEHEATIMHQIVRGYTDEQLELIATWFSEQR"
     gene            6173..7435
                     /locus_tag="P5537_10175"
     CDS             6173..7435
                     /locus_tag="P5537_10175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HRV78449.1"
                     /translation="MSLYRRDFLRATAAAAAALTLPRIARARARPHVVVVGGGFGGAT
                     AAKYLRMWSEGAVEVSLIEREAAFVSCPMSNLVIGGLKGMADITLDYERLRANWGVRV
                     ITDEALGVDPVRRSVRTARHGEIAGDRLVLAPGVAFESARIEGLAGNEERIPHAWKAG
                     PQTAILRAQLEAMPDGGVFAMTIPRAPYRCPPGPYERACVVAHYLRTTKPRSKLLVLD
                     ANEGIIAKKALFERAFARYGTMIEYRPNSTLLAVDAATREAEFEFERVRADVLNVIPP
                     MRAGELATRSGLALVNGAWAEVDWLAFGARGMPGVHVIGDAVFPAPGMPKSGHMANQH
                     AKVVAAAILNELAGLPPNPTPVVMNTCYSFVDDRSAMHVASVHQYDAAKAQLLPVPGA
                     GGLSEEASVAEGRTALKWAHHIWADTLD"
     gene            complement(7490..8119)
                     /locus_tag="P5537_10180"
     CDS             complement(7490..8119)
                     /locus_tag="P5537_10180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="c-type cytochrome"
                     /protein_id="HRV78450.1"
                     /translation="MKTSTSALARCVAGMGLSLGLAAAGAGELPKVDLARAAEISAAR
                     CGLCHGVDGDSSSPLYPRLASQHHQYIAKQLADFKAGRRKSDTMASMATDLTPEEMLA
                     LGVYFEQKPTKPRPARDVELAGVGRYIFHRGNESSGVAACAGCHGENGHGTEQLPRLA
                     GQVPRYIEDQLRSFNKRERTNDNAIMHSIASKLTELEIKGVAMYISSLE"
     gene            complement(8365..8805)
                     /locus_tag="P5537_10185"
     CDS             complement(8365..8805)
                     /locus_tag="P5537_10185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HRV78451.1"
                     /translation="MHAGIPTGVHVLCRREGRVLLMRRAGTGFFDGLFSLPGGHVEPG
                     ESVRAAARRELREETGLEVEEGALAWLGVVHRRSDTNRIDFFLAAERFAGEPAILEPH
                     KCDRLEWHAPEALPEHTVDYVRAALAAGPAPWILELGWEGAVPA"
     gene            complement(8805..9254)
                     /gene="dut"
                     /locus_tag="P5537_10190"
     CDS             complement(8805..9254)
                     /gene="dut"
                     /locus_tag="P5537_10190"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011764872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004170 - dUTP diphosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006226 - dUMP biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0046081 - dUTP catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HRV78452.1"
                     /translation="MHRIDVRLLDERLKTHPPAYATEGAAGLDLRACLPGPITLHPGE
                     TTLVPSGLAIHLSDPGLAAMVLPRSGLGHKHGIVLGNLVGLIDSDYQGQIFVSVWNRG
                     RATFTIEPMERIAQLVVVPVLQVGFNFVEGFEQSVRGADGFGSTGKH"
     gene            complement(9315..10511)
                     /gene="coaBC"
                     /locus_tag="P5537_10195"
     CDS             complement(9315..10511)
                     /gene="coaBC"
                     /locus_tag="P5537_10195"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0015939 - pantothenate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HRV78453.1"
                     /translation="MSMLSNRKIVLGVGGGIAAYKSAELVRLLGKAGAEVHVVLSEGG
                     ARFVTPVTYQALSGNPVWSDLWDARMPNHMAHIDLGRDADAILVAPATADFLARLAHG
                     HADDLLSTLCLARAVPLIVAPAMNRQMWESPPTQRNVAQIRADGVAVFGPAAGDQACG
                     EVGMGRMLEAEELLERLEGFFAPKLLAGRKVVLTAGPTFEALDPVRGITNISSGKMGY
                     ALACACAQAGAEVVLVSGPVCLAVPADVRRTSVTSALEMRDAVLAALPGADVFIGVAA
                     VADYRPLASAEHKLKKSADTLNIALTPNPDILAEVAARADAPFCVGFAAESRDLDAYA
                     EGKRRNKRLPMLVGNLVSDGMGGDDNTVILYDDAGRHPLPRAAKAEVARGIVAHLAGL
                     LPPRGR"
     gene            10589..11266
                     /gene="radC"
                     /locus_tag="P5537_10200"
     CDS             10589..11266
                     /gene="radC"
                     /locus_tag="P5537_10200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011236297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HRV78454.1"
                     /translation="MAITDWPADERPREKLLARGAAALSDAELLAIFLRVGIRGQSAV
                     DLARTLLSRFGSLTRMCGADANEFAAVPGMGLAKYAQLQAVMELSRRALAETLAERPL
                     FDSPQIVRDWLRLRLGHLPHETFCVLLLDARHCLIEAVDLFRGTLTQTSVYPREVVKL
                     ALARNAAAVILAHNHPSGAAEPSTADELLTRALKDALGLVDVRVLDHFVVPAHGHPVS
                     FAERGLL"
     gene            11414..11650
                     /gene="rpmB"
                     /locus_tag="P5537_10205"
     CDS             11414..11650
                     /gene="rpmB"
                     /locus_tag="P5537_10205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004335519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HRV78455.1"
                     /translation="MARVCQVTGKAPMVGNNVSHANNKTKRRFLPNLQSRRFWSEGEN
                     RWIRLRVSNAGLRTIDKKGIDVVVAELRARGEKL"
     gene            11676..11843
                     /gene="rpmG"
                     /locus_tag="P5537_10210"
     CDS             11676..11843
                     /gene="rpmG"
                     /locus_tag="P5537_10210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HRV78456.1"
                     /translation="MAKGIREKIKLESTAGTGHFYTTSKNKRTTPGKLEFNKYDPVAR
                     KHVPYKEVKLK"
     gene            complement(11985..12188)
                     /locus_tag="P5537_10215"
     CDS             complement(11985..12188)
                     /locus_tag="P5537_10215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006478030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HRV78457.1"
                     /translation="MATGTVKWFNDSKGFGFITPDDGSEDLFAHFSAINMSGFKSLKE
                     GEKVSFDVTQGPKGKQASNIQRA"
     gene            12576..12884
                     /gene="clpS"
                     /locus_tag="P5537_10220"
     CDS             12576..12884
                     /gene="clpS"
                     /locus_tag="P5537_10220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004335527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease adapter ClpS"
                     /protein_id="HRV78458.1"
                     /translation="MGTRKQDDLVLEAKRTRTRPPPLFKVMLLNDDYTPMDFVIVVLQ
                     KYFGMDRERATRVMLQVHREGMGVCGVFPRDIATTKVEQVTSFARQHQHPLACVMEEN
                     "
     gene            12885..15158
                     /gene="clpA"
                     /locus_tag="P5537_10225"
     CDS             12885..15158
                     /gene="clpA"
                     /locus_tag="P5537_10225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0043335 - protein unfolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpA"
                     /protein_id="HRV78459.1"
                     /translation="MIAQELEVSLHMAFVEARQKRHEFITVEHLLLALLDNPSAAQVL
                     KACAANIDELRRELTGFIEEHTPRIEGTDEIDTQPTLGFQRVIQRAILHVQSSGKKEV
                     TGANVLVAIFGEKDSHAVYYLQKQNISRLDVVNFISHGIAKAPPQGNPPQGRNEPEQG
                     EQEQEEKSSGGALESYTQNLNQQALVGKIDPLIGREKEVERVIQTLCRRRKNNPLLVG
                     EAGVGKTAIAEGLARRIVEGRVPEILENAQVFALDMGALLAGTKYRGDFEQRLKAVLK
                     QLIENPNAILFIDEIHTLIGAGAASGGTLDASNLLKPALSSGQLKCIGATTYNEFRQI
                     FEKDHALSRRFQKIDVVEPSVAETVEILKGLKSRFEEHHGIKYSNSALSSAAELSAKY
                     INDRHLPDKAIDVIDEAGAAQRILPKSKQKKTIGKNEIEEIVAKIARIPPRTVSNDDK
                     AALKTLERDLKNVVFGQNAAIEALAKAIKMSRSGLGNPQKPIGSFLFSGPTGVGKTEV
                     ARQLAYTLGIELVRFDMSEYMERHAVSRLIGAPPGYVGFDQGGLLTEQITKKPHSVLL
                     LDEIEKAHPDIYNILLQVMDHGTLTDNNGRQADFRNVIIIMTTNAGAEAMQKSVIGFS
                     AKREVGDEMADIKRLFTPEFRNRLDAMISFKALDNEIILRVVDKFLMQLEAQLHEKKV
                     EAHFSDELKAWLAEKGFDPLMGARPMARLIQDTIRSALADELLFGRLVNGGRVTIDLD
                     EDDKVKLVFEETEAATA"
     gene            15348..15827
                     /gene="rraA"
                     /locus_tag="P5537_10230"
     CDS             15348..15827
                     /gene="rraA"
                     /locus_tag="P5537_10230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008428 - ribonuclease inhibitor activity
                     [Evidence IEA];
                     GO_process: GO:0051252 - regulation of RNA metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E activity regulator RraA"
                     /protein_id="HRV78460.1"
                     /translation="MNIQTADLCDAHEDKLAVVAPMFASYGGRPSFGGPIATLKIFED
                     NSFVRKALESAGNGRVLVIDGGASMRCALVGDQLAELAVKNGWAGILVYGCIRDSKAI
                     GEMDLGVFALGTHPRKTVKRNVGEVDIPVSFGGVTFAPGHYVYADEDGVVVSAQPLV"
     gene            16362..17675
                     /gene="aceA"
                     /locus_tag="P5537_10235"
     CDS             16362..17675
                     /gene="aceA"
                     /locus_tag="P5537_10235"
                     /EC_number="4.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004451 - isocitrate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019752 - carboxylic acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate lyase"
                     /protein_id="HRV78461.1"
                     /translation="MTMTREQQIAALEKDWAENPRWKGVKRGYSAADVVRLRGSLQPE
                     YTLAQRGAKVLWDKVNGGAKKGYVNAFGAITAGQAMQQAKAGLEAVYLSGWQVAADGN
                     TSETMYPDQSLYAYDSVPTMVRRINNTFKRADEIQWSRGINPGDKEFIDYFLPIVADA
                     EAGFGGVLNAFELMKNMIAAGAAGVHFEDQLAAAKKCGHMGGKVLVPTREAVEKLISA
                     RFAADVMGVPTLILARTDAEAANLITSDYDANDKPFLTGERTQEGFFRVKNGLEQSIS
                     RGVAYAPYADLVWCETGVPDIGFAREFAQAVLAACPGKLLSYNCSPSFNWKKNLNDSQ
                     IASFQEELSALGYKYQFITLAGIHVNWFNTFKFAHAYARGEGMKHYVEMVQEPEFAAR
                     EMGYTFVSHQQEVGTGYFDDVTTVIQGGSSSVKALTGSTEEEQFH"
BASE COUNT         3083 a         6027 c         5766 g         2864 t
ORIGIN      
        1 gcttcatcca ctcggggcgc tgctcgtact gcaggctgga ctcggtggcg tagaggtctg
       61 cgttcgccgt gatcttctcg gcgttgacca ccatgcggcc gccagcgtcg gtctcgaggc
      121 cgaccgcctt gttgaccgtg gcgtgcaggt tcagcttggc catcgccgca acggccggcg
      181 cggtcgtgta cagcagggcg atgaagacca gcgcccaacc cgccgagcta cgcgcatcct
      241 tcaccgtcgg gacggtgaag aatcgcatga tgacgtgcgg caggcccgcg gtaccgatca
      301 tcagcgacag cgtgtacatg aacatgttga gcatgctgcc cggcatcgag gtcgtgtact
      361 ggtcgaagcc gaggtccttg accaccaggt cgagcttggc cagcagcgtg gtgtcggtgc
      421 ccgagatgtc ggaaccgagg ccgagctgcg gcagcgggtt gccggtgagc tgcagcgaga
      481 tgaagatcgc cggcaccagg taggccgaga tcagcacgat gtactgcgca acctgggtgt
      541 aggtgatgcc cttcatgccg ccgaacactg cgtacatgaa cacgatcgcc atgccgaggt
      601 agatgccggt ctcgctggag acgccgagga agcgcgagaa ggccacgccg acgccggtca
      661 tctggccgat gatgtaggtc agcgacgcgg tcagcaggca caccaccgcc accgtcgagg
      721 ccgtcttcga gtagaagcga tcgccgatga actgcggcac ggtgaacttg ccgaacttgc
      781 gcaggtacgg ggccagcagc atcgccagca ggacgtagcc gccggtccag cccatcagga
      841 acagaccgcc gccgtagccc atgttggcga tcaggccggc catggagatg aaggaagccg
      901 ccgacatcca gtcggccgcc gtggccatgc cgttggtgat cgggtggacg ctgccgcccg
      961 cggcatagaa ctcgctggtg ctgccggcac gcgcccagat ggcgatgccg atgtacagcg
     1021 cgaaggacgc gccgaccacc agataggtga ttgtctgaag atccatgtgt ctcccctgat
     1081 tattcttcgt ggacgtcgaa ctgacggtcg atgtcgccca tcttcttcgc gtaatagaag
     1141 atcagcgcga tgaagatgta gatcgacccc tggtgggcaa accagaaccc gagcggatag
     1201 cctcccagcg agatgctgtt cagcgcaggc gcaaagagga tgccggcacc gaacgagacc
     1261 acgaaccaga tgatcaggat cttggtcagg aggcccagcg tggctttcca gtagccggac
     1321 gcactgttgt tttccatcat gtctcctcgt tttaagtgaa acaccttcca ctgccggccc
     1381 gaaggctgga gacaccccgg accatgcagc agtggggcga ttatagaaag atcagtctta
     1441 cttatccctt acagagacgt aaggagtgag gcgcaaggcg taaggtgcgt gcaagaaaaa
     1501 cccgccggct ccgggggagc gggcgggttc gtcgccgccg gcgagggcgc cggccgagcc
     1561 aaggcttaca tccgggcgat catcgcgtcg ccgaactccg agcaggagac ctcgttggcg
     1621 ccttccatca ggcgggcgaa gtcgtaggtg acctgcttgt cggcgatcgc cgcttccatg
     1681 cccttgatca ccaggtcggc agcctccttc cagcccaggt ggcgcagcat catctcggcc
     1741 gacaggatca gcgagcccgg gttcaccttg tccagccccg cgtacttggg cgcggtgcca
     1801 tgggtggcct cgaagcaggc gtactggtcg gagatgttgg ctccgggggc gatgccgatg
     1861 ccgcccacct gtgcggcgag cgcgtccgag acgtagtcgc cgttgaggtt gagcgtggcg
     1921 atcacgtcgt attcggccgg acgcagcagg atctgctgca ggaaggcgtc ggcgatggcg
     1981 tccttgacga cgatctcgcg gccggtgttc gggttcttga acttgcacca cggcccgccg
     2041 tcgatcggct gcgcgccgaa ctcttcctgt gccaccttgt agccggtgtc gcggaacagg
     2101 ccctcggtga acttcatgat gttgcccttg tgcaccaggg tcacgctctt gcggtcgttg
     2161 tcgatcgcgt agcggatcgc ggcgcgcacg atacgggtcg tgccctcgat ggacaccggc
     2221 ttgataccga tgcccgaggt cgccgggaag cggatcttcc tgacccccat ctcgccctgc
     2281 aggaagtcga tgaccttctt cgcgccctcg gacagcgcct gccactcgat gccggcgtag
     2341 atgtcctcgg tgttctcgcg gaagatgacc atgtcggtca gctcgggctg cttgagcggg
     2401 ctgggcacgc ccttgaagta gcgcaccgga cgcacgcact ggtagaggtc gagttcctgg
     2461 cgcagcgcca cgttgagcga gcggatgccg ccgcccaccg gcgtggtcat cggccccttg
     2521 atcgacaccg aataggtctt gagcgcgtcg aaggtctcct tcggcagcca ctcgtcgggc
     2581 ccgtagatcc gcgtcgactt ctcgccggcg taaacctcca tccagtgaat cttcttccgg
     2641 ccgccatagg ccttgtcgac cgccgcgtcg atcaccttga tcatcaccgg ggtgatgtcg
     2701 acgccgatgc cgtcgccttc gatgaaggga atgatcggat tgtccggaac ggcctgcccc
     2761 gggacgatct tctggccgcc tgcgggtacc ttgatcttgg attcgctcat gcctgctccc
     2821 tcgctcaatg gccgtggatg gattccgcgg cgctgctgtg gccgaactgc cacggagacg
     2881 tccgtcgggc gacggaccgg aaggctgcga cggcatgcgg gacaagctgc aatccgccgc
     2941 acagccctct accggaggcc gattatgtcc caaagccccg cgggtcgaaa ggaagcggcg
     3001 cagcatggcc gcgccggcgg ggagacggcc ggtgatacca tttcaggcac gttcgacatc
     3061 gtcgcggccg cggcggcggc atcctccgga ggggttcgat ggacgtgcag tcgggagaaa
     3121 gcccggtcgc gcaggcgatc gcgcaggcgc tggtggaggg cttcaacaag cactaccgca
     3181 tctttcgcga gacctctcgc cgcgccaagg agctctatga ggccgcgcag tggcagaagc
     3241 agctcgacgc ggtgcgcgag cgcgtgcagt tctacgacga tcgtgtcgac gagacggtgc
     3301 agcgcctgca cgacgagttc gacgccgact cgctcgacga cagcacctgg ctgcaggtca
     3361 agctgcagtt catcggcatg ctgatcaacc accgccagcc cgagctcgcc gagaccttct
     3421 tcaactcggt caccaccaag atcctgcacc gcagctactt caacaacgac tacctgttcg
     3481 cgcgcccggc gatctccacc gagtacatcg agtcctaccc gccggtgtat tcgagctact
     3541 acccccgcga tcgcggcctg cgcgccacca tccggcgcat cgtcgaggac ttcgactggc
     3601 agcgcagctt cgaggacctc gaccgcgacg tcgacttcgt catgcgcgcg gcacaggccc
     3661 acctcggcga ctggccgccg atggaggtca actgccagat ccaggtgctg tactcggcct
     3721 tctaccgcaa caagaccgcc tacatcatcg gcaagacggt caacggctac caggaatatc
     3781 ccttcgcgat cgcggtgcgc cacaacgagc gcggcctgct ctacctcgac acgctgatcc
     3841 tcgacccgtg gcggatctcg gtgctgttct cgctgtcgcg cgcctacttc ctggtcgaca
     3901 tggaggtgcc ctcgggctac gtgcagttcc tgcgctcgat catgcccaac aagccgcgca
     3961 gcgagctcta caccatgctc ggcctgggca agcagggcaa gaccatgttc ttccgcgacc
     4021 tggtctcgca cctgcgccac tccaacgacc agttcatcgt cgcgccgggc atccgcggcc
     4081 tggtgatgct ggtgttcacg ctgccgtcct tcccctacgt gttcaagatc atcaaggacg
     4141 tgttcggcgc gtcgaagaac atggaccgcg ccaccgtcaa gcgcaagtac ctgatggtca
     4201 agcatgtcga ccgcgtcggg cgcatggcgg acacgctgga gttctcctac gccgcgctgc
     4261 cgctggcgcg cttccaccca gagctgctgg aagagctgcg cacgctggcg ccgtcctcgt
     4321 tcgagatcga cggcgacaag gtgatcatca agcacctcta catcgagcgc cgcatgaccc
     4381 cgctcaacct gcacctcgag aaggcgagcg acgcggagct ggaggaggcg gtcaaggagt
     4441 acggcaacgc catccgcgag ctcgcgatcg ccaacatctt ccccggcgac atgctttgga
     4501 agaacttcgg cgtcacgcgc tacggccgcg tcgtgttcta cgactacgac gagatcgagt
     4561 acatgaccga catgaacttc cgcaggatcc cgccggcgcc ctacgaggag atggagatgt
     4621 cgggcgagcc gtggtattcg gcggggccga tggacgtctt cccggaggag ttcgccacct
     4681 tcctgcttgg cgtgccccgg gtgcgcaagg ccttcctcag gcaccaccgc gacctgctcg
     4741 cgccgaagtt ctggcaggac gcgcagcagc gcatccgcga cggctacgtc gaggacttct
     4801 tcccctaccc ggtcgagctg cgcttctgca agctgtttcc gccggccgcg ggcgccgcct
     4861 gaggccgcgg ccgcggtgct caggccgctg cgccgccgat ctgcacctgg tcgctgcggg
     4921 tctcgccgcg gctatcgacc cagctcgcca ccaggcgatc gcccgccgcc gcgcccttga
     4981 agcggaagcg caggaagggg tttgccgaga ccgaagggcc gaactccgca ctgaagacca
     5041 cacgctcgcc gtggcggacc tcgagttgcg tgatgaagtg cgcggggatg accgcgccct
     5101 tgtcgtcctt gcgctggccg ctctccatcg gatggggaac ctgcatgcga acgtcggtga
     5161 cgccgtcgcg gacgtccgcg cggatgcgca tcggatttgc catggattcg ctctcctgtg
     5221 ccggcgcagc ctcagccgca gccgctgatg gtgacgatga ccgccttgcg ggcgacgtgg
     5281 aaacgcccgc cggcgcgcac cagcgcgacc acgtcggcgc tctgcgccat cttcagccgg
     5341 gtgatcacct cgggctgggt accctccggg atggaaaaca ccgcggcgag cggaaagggg
     5401 ttcttctcga ccaggatcgc gatgcggtcg gtgccgggca ggcgactcct gacctcgacc
     5461 gagaccgcgt tggcgacctc ggcgatgtcg ggggcggtga ggctcagctc ggtgctcgcc
     5521 gtggcgtcct gcgcacccag cgcggcgagc gcggcattga gttcgcgcgc gtcgaagccg
     5581 ggccgcgcgg cggcggcctg cgcctgcgcg ggcgagatca gcccggcctg ggcgagcatg
     5641 cccagcacgc ccagaccgcc ggcggcgcgc agcacttgtc ttcgttttcg gtccatccgg
     5701 ttctcctgca ggaaatcggg cggcaggccg cgggaggccc ccctgccggc cgcggtggca
     5761 gcgcgtggct gccgagggcg gctatactcg cacagctggc gccgccctgg cgcagcgcag
     5821 catcgtccgc acccttcggg cgcccactcg aggcagcaag cacaatgacg aacagactcc
     5881 tcgccagcgc attcgttctg gcctgcgcgg tcgctcccgc gcaggccgcc gacccccacc
     5941 tggcgcgcaa cctcgccgcc acctgcgcca actgccacgg caccggcgga cgcagcgtgt
     6001 acgagccgct ggtgggacgg ccgcgcgaga agctgctgag catgctggcc gatttccgct
     6061 cgggcgagca cgaagcgacg atcatgcacc agatcgtgcg cggctacacc gacgagcagc
     6121 tcgagctgat cgccacctgg ttctccgaac agcgctgagg aagaggaaac gcatgagcct
     6181 gtaccgacgc gacttcctgc gcgccaccgc ggcagccgcc gccgcgctca cccttccccg
     6241 catcgcccgc gcccgcgcac gcccccacgt cgtggtggtg ggcggcggct tcggcggcgc
     6301 caccgcggcc aagtacctgc gcatgtggag cgagggcgcg gtcgaggtca gcctgatcga
     6361 gcgcgaagcc gccttcgtgt cctgcccgat gtccaacctc gtgatcggcg gcctcaaggg
     6421 catggcggac atcaccctcg actacgagcg cctgcgcgcg aactggggcg tgcgcgtgat
     6481 caccgacgag gcgctcggcg tcgatcccgt ccgccgcagc gtacgcaccg cgcgccacgg
     6541 cgagatcgcc ggcgaccgcc tcgtgctcgc ccccggcgtg gccttcgagt cggcgcgcat
     6601 cgagggcctg gccggcaacg aggagcgcat cccgcacgcc tggaaggcgg gaccgcagac
     6661 cgccatcctg cgcgcccagc tcgaggccat gcccgacggc ggcgtgttcg cgatgaccat
     6721 cccgcgcgcg ccctaccgct gcccgcccgg cccctacgag cgtgcctgcg tggtcgccca
     6781 ctacctgcgc accaccaagc cgcgctcgaa gctgctggtg ctcgacgcca acgagggcat
     6841 catcgccaag aaggcgctct tcgaacgcgc cttcgcgcgc tacggcacaa tgatcgaata
     6901 tcgccccaac agcacgctgc tggcggtgga cgccgccacg cgcgaggccg agttcgagtt
     6961 cgagcgcgtg cgtgccgacg tcctcaacgt gatcccgccg atgcgtgccg gcgagctcgc
     7021 cacgcgcagc ggcctggccc tggtcaacgg cgcctgggcg gaggtcgact ggctcgcctt
     7081 cggcgcgcgc ggcatgcccg gcgtgcacgt gatcggcgac gcggtgttcc ccgcccccgg
     7141 catgccgaag tccggccaca tggccaacca gcacgccaag gtggtcgcgg cggcgatcct
     7201 caacgaactg gccgggctgc cgcccaatcc cacgccagtg gtgatgaaca cctgctacag
     7261 cttcgtcgac gaccgctccg ccatgcacgt ggcctcggtg caccagtacg acgccgccaa
     7321 ggcccagctg ctgccggtgc cgggcgcggg cgggctgtcg gaggaggcca gcgtggccga
     7381 gggccgcacc gcgctgaagt gggcgcatca catctgggcc gacaccctgg attgagcggc
     7441 tggggaggcc cacgccccgg cgagcggcgc cgcaggcact gcgaggggat tactcgagcg
     7501 agctgatgta catcgccacg cccttgatct cgagctcggt gagcttggag gcgatcgagt
     7561 gcatgatggc gttgtcgttg gtgcgttcgc gcttgttgaa cgagcgcagc tggtcctcga
     7621 tgtagcgtgg cacctgcccg gccagacgcg gcagctgctc ggtgccgtgg ccgttctcgc
     7681 cgtggcagcc ggcacaggcc gccacgccgg aggattcgtt gccgcgatgg aagatgtagc
     7741 gccccacccc agcgagctcg acatcgcgcg ccgggcgcgg cttggtcggc ttctgctcga
     7801 aatagacgcc gagcgcgagc atttcttccg gcgtgaggtc cgtcgccatg ctcgccatgg
     7861 tgtcgctctt gcgtcgcccg gccttgaagt cggcgagctg cttggcgatg tactgatggt
     7921 gctggctggc gaggcgcggg tagagcggcg acgaactgtc gccatcgacg ccgtggcaga
     7981 gcccgcagcg cgccgcgctg atctcggccg cgcgcgcgag atcgaccttg ggaagctcgc
     8041 cggcgcctgc cgcggcgagc ccgagggaaa gccccatgcc cgccacgcag cgggcgagcg
     8101 cactggtcga agtcttcatg ccttggttct cctgtggccg cacgcagcgt cggcgcagcg
     8161 taggtgaggt gaggtgagcg attgctgcaa tgataccaag cacccgcagt cacttcgcgg
     8221 cgtcaggctt cttgtaggag cgccggcagg cgcgaaggcg gcggagggtg gcacgcgcgt
     8281 cgacttcggc acggccttgt tcgcagctgc cgcaactcct acagaggatc ggagacgtag
     8341 cggttcctgt aggagcgccg gcgcctacgc cgggacggcc ccctcccaac cgagctccag
     8401 aatccacggt gccggtccgg ctgcgagcgc ggcgcgcacg taatcgaccg tgtgctcggg
     8461 aagggcctcg ggagcgtgcc attcgaggcg gtcgcacttg tgcggctcga ggatggcggg
     8521 ctcgccggcg aagcgctcgg cggcgaggaa gaaatcgatg cggttggtgt ccgagcggcg
     8581 atggacgacg cccagccagg cgagcgcccc ctcctcgacc tccagcccgg tctcctcgcg
     8641 caactcgcgc cgcgccgccg cgcgcacgga ctcgccgggc tcgacgtgcc cgccgggcag
     8701 gctgaagagg ccgtcgaaga aaccggtgcc ggcgcggcgc atcagcagca cgcggccctc
     8761 gcgccggcac agcacgtgta caccggttgg aatccctgcg tgcatcaatg cttgcccgtg
     8821 ctgccgaagc cgtccgcccc gcgcacgctc tgctcgaagc cctcgacgaa gttgaagccg
     8881 acctgcagca ccggcaccac cacgagctgg gcgatgcgct ccatcggctc gatggtgaag
     8941 gtcgcacgcc cgcggttcca caccgacacg aagatctgcc cctggtagtc ggagtcgatc
     9001 agccccacca ggttgccgag cacgatgccg tgcttgtggc cgagcccgga gcgcggcagc
     9061 accatcgccg ccagcccggg gtcggagaga tggatcgcca gcccgctggg caccagcgtc
     9121 gtctcgcccg gatgcagggt gatcggtccc ggcaggcagg cgcgcaggtc gagcccggca
     9181 gcgccctcgg tggcgtaggc agggggatgg gtcttgaggc gctcgtcgag cagcctgacg
     9241 tcgattcgat gcatgtcggc tctccttgcc ggcgggcggc gcgtggcacg cccggccttt
     9301 cgttgcggtt tcgctcagcg cccccggggc ggcagcaggc cggcgaggtg ggcgacgatg
     9361 ccgcgcgcca cctcggcctt ggcggcgcgc ggcagcgggt ggcggccggc gtcgtcgtag
     9421 aggatcacgg tgttgtcgtc gccccccatg ccgtcgctga cgaggttgcc gaccagcatg
     9481 ggcagccgct tgttgcgccg cttgccctcg gcgtaggcgt cgaggtcgcg gctctcggcg
     9541 gcgaagccga cgcagaacgg cgcatctgcg cgcgcggcga cctcggcgag gatgtcgggg
     9601 ttgggggtca gcgcgatgtt cagtgtatcg gcggattttt tcagcttgtg ttcggcgctc
     9661 gcgagcggac ggtagtccgc caccgcggcc acgccgatga agacgtccgc gcccggcagc
     9721 gcggcgagaa ccgcgtcacg catctccagc gcactggtca cgctcgtgcg cctcacgtcg
     9781 gccggcaccg ccaggcacac cggcccgctc accagcacca cctccgcgcc ggcctgggcg
     9841 caggcgcacg cgagcgcgta gcccatcttg cccgagctga tgttggtgat gccgcgcacc
     9901 ggatcgagcg cctcgaaggt cggcccggcg gtgagcacga ccttgcgccc ggcgagcagc
     9961 ttgggcgcga agaagccctc gaggcgttcg agcagctcct cggcctcgag catgcgcccc
    10021 atgccgacct cgccgcaggc ctggtcgccc gccgcggggc cgaacacggc gacgccgtcg
    10081 gcgcggatct gcgcgacgtt gcgctgcgtc ggcggcgact cccacatctg gcggttcatc
    10141 gccggcgcca cgatcagcgg caccgcgcgc gccaggcaca gcgtgctgag caggtcgtcg
    10201 gcgtgaccgt gcgcgaggcg ggcgaggaag tcggcggtcg cgggagcgac caggatcgca
    10261 tcggcgtcgc ggccgaggtc gatgtgcgcc atgtggttgg gcatgcgcgc atcccacagg
    10321 tcggaccaca ccgggttgcc ggaaagcgcc tggtaggtca ccggggtcac gaagcgcgcc
    10381 ccgccctcgc tcagcaccac gtggacctcg gcgccggcct tgccgagcag gcgcaccagt
    10441 tcggccgact tgtacgctgc gatgccgccg ccgaccccga ggacgatctt gcgattgctc
    10501 aacatgctca tgacgatgga ctatactcca cgacgaatcg atgcattctg gatgggccgg
    10561 caggccgcga cgagggagcg gacaaacgat ggcgatcacc gactggccgg cggacgagcg
    10621 tccgcgcgag aagctgctcg cccgcggcgc cgcggcgctg tccgacgcgg agctgctggc
    10681 gatcttcctg cgcgtgggca tccgcggaca gagcgcggtg gatctcgccc gcacgctgct
    10741 gtcccgcttc ggcagcctga cccgcatgtg tggcgccgac gcgaacgagt tcgcggcggt
    10801 gccgggcatg gggctggcga agtatgccca actgcaggcg gtcatggaac tgtcgcggcg
    10861 ggcgctcgcc gagaccctgg ccgagcgccc gctgttcgat tcgccccaga tcgttcgcga
    10921 ctggctgcgc ctgcgcctcg ggcacctgcc gcacgagacc ttctgcgtgc tgctgctcga
    10981 cgcccgccac tgcctgatcg aggcggtgga cctctttcgc ggcacgctca cccagacctc
    11041 ggtatatccg cgcgaggtgg tcaagctcgc cctcgcgcgc aacgccgcgg cggtgatcct
    11101 cgcccacaac cacccctccg gcgccgccga gccgagcacc gccgacgaac tgctcacgcg
    11161 cgccctgaag gacgcgctcg gcctggtcga cgtgcgcgtg ctcgatcatt tcgtggtgcc
    11221 ggcgcacggt catccggtat cattcgccga acgcggcttg ctctgaggtc ccgtccgccc
    11281 ttgcgctcgg accccggccc ctgcctggca ccctaccctg cgaacacgat gatggtgcgc
    11341 ggggcttgcc tcgacagcgc ctcttgcatt atcctcgcac gttttccgca atcagaattc
    11401 cctggagcat cgtatggctc gcgtctgcca agtgaccggt aaagcaccga tggtgggaaa
    11461 taacgtttcc cacgccaaca acaagaccaa gcgtcgtttc ctgcccaacc tgcagagccg
    11521 ccgcttctgg agcgaaggcg agaaccgctg gatccgcctg cgcgtgtcca acgccggtct
    11581 gcgcacgatc gacaagaaag gcatcgacgt cgtcgttgcc gagcttcgcg cccgcggcga
    11641 gaagctgtaa gcaaccgcac tgaacggaga acgccatggc caagggcatc cgcgaaaaga
    11701 tcaagctgga gtcgaccgcc ggtacgggtc acttctacac cacctcgaag aacaagcgca
    11761 ccacgcctgg aaagctcgag ttcaacaagt acgacccggt cgcgcgcaag cacgtgccgt
    11821 acaaggaagt gaagctgaag tgatttgacg cggcggttgt acgcaaccgc ccggcgggac
    11881 gcagcagctc cagaaaaccg gaagggccat cggatgatcc gatggccctt ctgttttttc
    11941 acccgccacc ggcggtggcg aatgcgatca cgagcgtcgc agaatcacgc gcgctggatg
    12001 ttcgaggcct gcttgccctt gggaccctgg gtgacgtcga aggaaacctt ctcgccttcc
    12061 ttcaggctct tgaaaccgct catgttgatg gcggagaaat gcgcgaacag gtcttcactt
    12121 ccatcatccg gcgtgatgaa accaaaaccc ttggaatcgt tgaaccactt cacggtacca
    12181 gttgccatat tgcttgaatc cttcaaggtt gcttgttaca ccgcgacttt cgcagaccgc
    12241 ggtcgtgtcg gcgctgacag ggaccaaaac cacctccgga agcccctcgg gatcaggctc
    12301 gagccggcgc acgtcttagt ttttacgcat tcgccacgac agcgtcaacg ggatttcgcg
    12361 ggctctcgat cgcgcagcgc aacatgaaaa gacccggaaa gccctgatcc cgggcgcaat
    12421 ttcacgcggg ctgcgggcat gcgttcatgc cgcagcgcaa gaatgccgat ctgcaccgtg
    12481 cacgccaaac cacactccgc gcgaggtttt cagcggactc gacatgcgca cgcggcgcgt
    12541 gttgcactct gcttcgactt cattagaatg attttatggg cacccgaaaa caagacgatc
    12601 tggtcctgga agccaagcgg acgcgcacgc gcccgccgcc gctcttcaag gtcatgctgc
    12661 tgaacgacga ctacacgccg atggacttcg tcatcgtcgt cctgcagaaa tatttcggca
    12721 tggatcgcga acgtgccacg cgagtcatgc tccaagtcca cagagagggc atgggggtat
    12781 gcggcgtctt tcccagggac atcgccacga ccaaggtgga gcaggtcacc tcgtttgctc
    12841 gtcagcatca acatccgctg gcatgcgtga tggaggaaaa ttgaatgatc gcgcaagagc
    12901 ttgaagtcag cctgcacatg gctttcgtcg aggcacggca aaagcgccac gagttcatca
    12961 ccgtggagca tctgctgctt gccctgctgg acaacccttc ggccgcacag gtgctgaagg
    13021 cgtgcgccgc caacatcgac gaactgcgcc gcgagctgac cggtttcatc gaagaacaca
    13081 ccccgcgcat cgaaggcacg gacgagatcg acacccagcc cacgctgggt ttccagcgcg
    13141 tgatccagcg cgcgatcctg cacgtgcagt cctcgggcaa gaaggaagtc accggcgcca
    13201 acgtgctggt ggcgatcttc ggcgagaagg actcgcacgc ggtgtattac ctgcagaagc
    13261 agaacatctc gcgcctggac gtggtgaact tcatctccca tggcattgcc aaggcgccac
    13321 cgcagggcaa cccgccgcag ggccgcaacg aacccgagca gggcgagcag gagcaggagg
    13381 agaagtcctc cggcggcgcg ctcgagagct acacgcagaa cctcaaccag caggcgctgg
    13441 tcggcaagat cgacccgctg atcggccgcg agaaggaggt cgagcgcgtc atccagaccc
    13501 tgtgccgccg gcgcaagaac aacccgctgc tggtcggcga ggccggcgtg ggcaagaccg
    13561 cgatcgccga aggcctcgca cggcgcatcg tcgagggccg cgtgcccgag atcctcgaga
    13621 acgcgcaggt gttcgcgctc gacatgggtg cgctgctcgc cggcaccaag taccgcggcg
    13681 acttcgagca gcgtctcaag gcggtgttga agcagctcat cgagaacccg aacgcgatcc
    13741 tgttcatcga cgagatccac actctgatcg gtgcgggtgc ggcctcgggc ggcacgctcg
    13801 acgcatccaa cctgctcaag ccggcgctgt cctcgggcca gctcaagtgc atcggcgcga
    13861 ccacctacaa cgagttccgc cagatcttcg agaaggacca cgccctgtcg cggcgtttcc
    13921 agaagatcga cgtggtcgag ccctcggtgg ctgagacggt cgagatcctc aaggggctca
    13981 agagccgctt cgaggaacac cacggcatca agtacagcaa ctcggcgctc tccagcgccg
    14041 ccgagctgtc ggccaagtac atcaacgacc gtcacctgcc cgacaaggcg atcgacgtca
    14101 tcgacgaggc cggcgccgcc cagcgcatcc tgcccaagtc gaagcagaag aagaccatcg
    14161 gcaagaacga gatcgaggag atcgtcgcca agatcgcccg catcccgccg cgcaccgtgt
    14221 ccaacgacga caaggccgcg ctgaagacgc tcgagcgcga cctcaagaac gtcgtcttcg
    14281 gccagaacgc cgccatcgag gcgctcgcca aggcgatcaa gatgtcgcgc tcggggctgg
    14341 gcaacccgca gaagccgatc ggttccttcc tgttctccgg cccgaccggc gtcggcaaga
    14401 ccgaggtcgc ccgccagctc gcctacacgc tgggcatcga gctggtgcgc ttcgacatgt
    14461 ccgagtacat ggaacgccac gcggtcagcc gcctgatcgg cgcgcccccg ggctatgtcg
    14521 gcttcgacca gggcggcctg ctcaccgagc agatcaccaa gaagccgcat agcgttctgc
    14581 tgctcgacga gatcgagaag gcgcacccgg acatctacaa catcctgctg caggtcatgg
    14641 accatggcac gctgaccgac aacaacggcc gccaggcgga tttccgcaat gtgatcatca
    14701 tcatgaccac caacgcgggt gccgaggcga tgcagaagtc ggtgatcggc ttctcggcca
    14761 agcgcgaggt cggtgacgag atggccgaca tcaagcgcct gttcacgccg gagttccgca
    14821 accgcctgga tgccatgatc tcgttcaagg cgctcgacaa cgagatcatc ctgcgcgtgg
    14881 tcgacaagtt cctgatgcag ctcgaggcgc aactgcacga gaagaaggtc gaggcccact
    14941 tcagcgacga gctcaaggcc tggctggccg agaagggctt cgatccgctg atgggcgcgc
    15001 gtccgatggc acgcctgatc caggacacca tccgctccgc gcttgccgac gagctgctgt
    15061 tcggccgcct ggtcaacggc ggcagggtga ccatcgacct ggacgaggac gacaaggtga
    15121 agctcgtctt cgaggagacg gaagcggcca cggcctgagc gatcctcgcc ggaagacttc
    15181 cggcgcatac cggaaacggc atgtccgcag cctggacatg ccgtttttca ttgcggacgg
    15241 acacctgccg attcgcgtgc ggtcgcgctg cagtcgtcgt cgtttatgat gcgcgctccc
    15301 gcgccggcca cccggcgcac cgcccccttc cttttcgagg agccagcatg aacatccaga
    15361 ccgccgacct ctgcgacgcc cacgaagaca agctcgccgt cgtcgccccc atgttcgcca
    15421 gctacggcgg ccgcccgtcc ttcggcggac cgatcgcgac gctgaagatc ttcgaggaca
    15481 actccttcgt gcgcaaggcg ctggagagcg ccggaaatgg ccgcgtgctg gtgatcgacg
    15541 gcggcgcctc gatgcgctgc gccctggtcg gcgaccagct cgccgaactc gcggtgaaga
    15601 acggctgggc cggcatcctc gtctacggct gcatccgcga ctcaaaggcg atcggcgaga
    15661 tggacctcgg cgtgttcgcg ctggggaccc acccgaggaa gaccgtcaag cgcaacgtcg
    15721 gcgaggtcga catcccggtg agcttcggcg gcgtcacctt cgcacccggg cactatgtct
    15781 acgccgacga ggacggcgtg gtcgtaagcg cgcagccctt ggtttgagag actacaggcg
    15841 tcaggcgtgc gcctgcaggc gctgcgcagc gtgcgcccgg gcggctgcag aggttccgct
    15901 cgcgggacgg agcgagcgca ctccctacgc gcaggatcgc ggctcgcacc cggcctgtcg
    15961 ggcggctgtg gtgcctcctg tcggagcggc ggccgccgcg gatgcggccg cgcggcgatc
    16021 gacgcgggcg acgaaggccg ctgccgtgtt cgagcctgct cgcgcacctg cggaaacgag
    16081 cggggcgtgc aatgcagcag agccagtccg cctttccgtt tcacagcgct ccatttcttt
    16141 tcacgataca aaacacgaaa agcaaatcat tgttttaaaa cagaaagatt ttttcttatg
    16201 tcttatataa gacatattgc tgctgcgcgg aatgcctcct atactctctt cccatctgca
    16261 gcgccctttc tccctcgaaa accgctgcag ccggaacacc gcgaccggta cctgaacccg
    16321 ccgcgatgcc tgaccccctc ctgcattcat aaggacgcat catgaccatg acccgcgaac
    16381 agcaaatcgc cgccctcgaa aaagactggg ccgagaatcc ccgttggaaa ggcgtcaagc
    16441 gcggctactc cgcggccgac gtggtccgcc tgcgtggcag ccttcagccc gagtacaccc
    16501 tggcgcagcg cggcgccaag gtgctgtggg acaaagtgaa tggcggcgcc aagaaaggtt
    16561 acgtgaatgc cttcggtgcc atcaccgccg gtcaggccat gcagcaggcc aaggccggcc
    16621 tcgaggccgt gtatctgtcc ggctggcagg tcgccgccga cggcaacacc tccgagacca
    16681 tgtaccccga ccagtcgctg tacgcctacg actcggtgcc gaccatggtc cgccgcatca
    16741 acaacacctt caagcgcgcc gacgagatcc agtggtcgcg cggcatcaac ccgggcgaca
    16801 aggaattcat cgattacttc ctgccgatcg tcgccgacgc cgaggccggt ttcggtggcg
    16861 tgctgaacgc cttcgagctg atgaagaaca tgatcgccgc cggtgctgcc ggtgtgcact
    16921 tcgaagacca gcttgcggcc gccaagaagt gcggtcacat gggtggcaag gtgctcgtcc
    16981 cgacccgcga agccgtcgag aagctgatct ccgcacgttt cgccgccgac gtcatgggcg
    17041 tgccgaccct gatcctggcc cgtaccgacg ctgaagcggc taacctgatc acctccgact
    17101 acgacgcgaa cgacaagccc ttcctcaccg gcgaacgcac ccaggaaggc ttcttccgcg
    17161 tcaagaacgg cctggaacag tccatctccc gcggcgtcgc ttatgccccg tacgccgacc
    17221 tggtgtggtg cgaaaccggc gtgcccgata tcggcttcgc gcgtgagttc gctcaagccg
    17281 tgctggcagc ctgcccgggc aagctgctgt cgtacaactg ctcgccgtcc ttcaactgga
    17341 agaagaacct caacgactcg cagatcgcat ccttccagga agagctgtcc gcgctgggct
    17401 acaagtatca gttcatcacg ctggccggca tccacgtcaa ctggttcaac accttcaagt
    17461 tcgcccacgc ttacgctcgc ggcgaaggca tgaagcacta cgttgaaatg gttcaggaac
    17521 cggaattcgc agcgcgcgaa atgggctaca ccttcgtctc gcaccagcag gaagtcggta
    17581 ccggctactt cgacgacgtc accaccgtga tccagggcgg ttcgtcctcg gtcaaggcgc
    17641 tgaccggctc gaccgaagaa gagcagttcc actaagagac tgcttccctc ataacggggg
    17701 aggagacgag aggccatcct gcgggatggc cttttttcgt
//
LOCUS       DAOTIN010000060        17705 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_3839_length_17705_cov_8.041076, whole genome shotgun sequence.
ACCESSION   DAOTIN010000060 DAOTIN010000000
VERSION     DAOTIN010000060.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 17705)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 17705)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17705
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3839_length_17705_cov_8.041076"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..618)
                     /locus_tag="P5537_10240"
     CDS             complement(<1..618)
                     /locus_tag="P5537_10240"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78462.1"
                     /translation="MLASLTHNLTGTAQDQTTAYTRNQVQEIVGQNWTNDLYQWTGYA
                     NGTQSYTANGLNQYTAAAGATLTHDARGNLTGDGVWTYTFDADNKLKSATKTGYAATL
                     AYDAEGRLRRTTLAGAITDLAYDGVDLVAEYDGAGTLLRRYVHGPGVDEPLVWYEGST
                     TTNKSWLYADHLGSIIGTANSAGTSTAIHSYGPFGEPNVTTGVPMM"
     gene            727..1008
                     /locus_tag="P5537_10245"
     CDS             727..1008
                     /locus_tag="P5537_10245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011236962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HRV78463.1"
                     /translation="MPAATSTARLEARISTDLHSMLKRAAELQGRTMTDFVVAAVQDA
                     AQRAIEQAEVIRLSLADQECFAQALLSPPQPAPALERAFARRRKLLRAE"
     gene            1005..1526
                     /locus_tag="P5537_10250"
     CDS             1005..1526
                     /locus_tag="P5537_10250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011254834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HRV78464.1"
                     /translation="MSSAPFRLTPLDAAHARAAFNCGSEPLERYLREQVTQDVRRRVA
                     ACFVALAEGQRIAGYYTLASASLLLADLPASVGKKLPRYPTVPAVRMGRLAVDQAFKG
                     QGLGGALLADALDRAVRSEIAAYALMVDAKDEAAAAFYRHHGFIALPDSPFTLFLPLA
                     TLEASRKTENRAR"
     gene            1648..1916
                     /locus_tag="P5537_10255"
                     /pseudo
     CDS             1648..1916
                     /locus_tag="P5537_10255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138064.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4158 domain-containing protein"
     gene            1947..2561
                     /locus_tag="P5537_10260"
     CDS             1947..2561
                     /locus_tag="P5537_10260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2238 domain-containing protein"
                     /protein_id="HRV78465.1"
                     /translation="MKLRLALLILVLAALLASGIAPYDRGVWWAEVAPVLIALPILLA
                     SARRFPLTPLTYGLIAFFSLILILGGAYTYARVPVGFVVQDWFELARNPYDRFGHFFQ
                     GVTPAILGRELLLRTSPLRPGKWLFALLTLSCTGISALYELVEWASAELWAGGAVEFL
                     GTQGDPWDAQSDMLMALLGAIIAQIVFGRLHDRQLARLAAQPST"
     gene            complement(2902..>4661)
                     /locus_tag="P5537_10265"
     CDS             complement(2902..>4661)
                     /locus_tag="P5537_10265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Lon protease family protein"
                     /protein_id="HRV78466.1"
                     /translation="GWRKSVRESIDRAEREVLGPAVAHLLREVRDAHEDLPAVLAFLD
                     AVERDVIDSAVRGTMLDEEDDEAPEPEENTRYHRYQVKLLVDHSGSQGAPVVFENNPG
                     YGNLIGRIEHIVQQGNQVSHFNLIRAGALHRANGGYLVLDAERLLSQPFAWEGLKRSL
                     RAGEIRIEPPAEAQGWSGALTLEPEAVPSALKVVLIGDREVYYLLMEHDPEFADLFKV
                     AADFNDDILRTPENECEYARLMALLARGAKLLAVERSGVARLVEEASRLAEDSGRLSL
                     NTRALSDLMREADFHARQKGLAATTRAEVEDALAARARRANRYPTRVLESILDGTTLI
                     STTGERAGQINGLVVIELAGEHFGHPVRITATVRMGEGDVVDIERETELGGAIHSKGV
                     LILSAFLAARYARHQPLSLSASLVFEQSYAPVEGDSASLAELCALLSALTQVPIQQRF
                     AITGSVNQFGEVQVIGGVNEKIEGFFDLCSARGLDGTQGVVIPAASVRHLMLREDVVQ
                     AAAEGRFHIHAVKTVDEAMTVLTGVEAGEPDAKGVIPKGTLNHKIATVLAEMTAARHA
                     YSDAEGAAGARQHRRRHGV"
     assembly_gap    4662..4761
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            5023..6102
                     /gene="moaA"
                     /locus_tag="P5537_10270"
     CDS             5023..6102
                     /gene="moaA"
                     /locus_tag="P5537_10270"
                     /EC_number="4.1.99.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HRV78467.1"
                     /translation="MKVIPIQQAASPLAPADPALVPAPGAALVDRRARNVRDLRISVT
                     DRCNFRCVYCMPREVFGDDYAFLPRRQLLSFEEILRVARLFAARGVRKIRITGGEPLL
                     RKDVDRLIGMLATLDGVEITLTTNGVLLPKLARRLKDAGLHRVTVSLDALDDALFRRM
                     NDADYPVDKVLEGIEAARAVGLGPIKVNMVVKRGTNDSDIEPMAAHFRNSGHILRFIE
                     FMDVGASNGWKMDEVLPSREVVARIDRLFPLEPVDPNYEGEVAERWRYKDGAGEIGVI
                     SSVTQAFCSSCTRIRLSTEGQLYTCLFAQQGHDLRALLREGADDARIDAAIAQVWQGR
                     EDRYSEIRTAETAALRKIEMSYIGG"
     gene            complement(6137..6754)
                     /locus_tag="P5537_10275"
     CDS             complement(6137..6754)
                     /locus_tag="P5537_10275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceI family protein"
                     /protein_id="HRV78468.1"
                     /translation="MESRRCISRTLAATALAGVLGAAPAWAEPRSYTIDPDHFAIGFQ
                     VDHIGYADIIGMFLKASGRFEYDEAARTLKSGRVVVAADSVFSNHEARDRHVRDSDFL
                     DAKKHPEIVFEATAFEPGGERDGRLEGRLAGRLTLLGQTHPVVLDVTLNKAATYPFGH
                     RKHTLGISARTTIERSRWGMDYGISRGMVGDAVELRFELEAMRDD"
     gene            complement(6858..7601)
                     /locus_tag="P5537_10280"
     CDS             complement(6858..7601)
                     /locus_tag="P5537_10280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HRV78469.1"
                     /translation="MKAMEQGGSCVRRGGLPRLWLELAGGFGGLVALLALAITTLALP
                     AGAAWAAGAVLLAISALILRFRRESRGGLGPANCVTLGRALLVAALAGALAAPGWVGE
                     HAVAVAVLAAIALLLDGVDGWVARRWHCESDFGARFDMELDAFLILVLCVHLLAMGKA
                     GPWVLAIGAMRYAFVAAMQPWPWLERPLPESRRRKLVCVWQVASLLVCLLPVIAGALA
                     TMLLALALALLAWSFAVDVRWLYRSRPRT"
     gene            7806..8804
                     /locus_tag="P5537_10285"
     CDS             7806..8804
                     /locus_tag="P5537_10285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002930082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HRV78470.1"
                     /translation="MSAPNLAFWTVRPGCGELRPAPLPPPGAGEVLVRNLYGAVSRGT
                     EGLVFRGEVPESEYQRMRAPFQEGDFPGPLKYGYIGVGVVEDGVGDAAAALRGRTVFC
                     LHPHQQRYVVPADAVVPLPEGVPAARAVLAANLETAINACWDGAPAVGDRVAVVGAGV
                     LGSLVAWLCARIPGVELELIDTDPGRARLAEALGLVHRLPDQARGDCDLVFHASGNPA
                     GLVRALELAGQDATVMEMSWYGRRSAELPLGAAFHARRLRLQSSQVGRLPPQRSPRWD
                     YRRRMELALALLVDPRMDALISGETDFTELPALMQRLADAPAGALCERIRYDGPTP"
     gene            8835..9233
                     /locus_tag="P5537_10290"
     CDS             8835..9233
                     /locus_tag="P5537_10290"
                     /EC_number="4.1.2.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070497 -
                     6-carboxy-5,6,7,8-tetrahydropterin synthase activity
                     [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-carboxytetrahydropterin synthase"
                     /protein_id="HRV78471.1"
                     /translation="MYSLTVREHIMIAHSFRGEIFGPAQKMHGATYLVDACFQRSELD
                     ADGLVVDIGLAAETLKAVLAEFNFRNLDELEEFRGRNTTTEFMARVVFDRLAAAIRAG
                     RIGPGAKGLERLKVSLHESHVAWASYEGTL"
     gene            9316..10377
                     /locus_tag="P5537_10295"
     CDS             9316..10377
                     /locus_tag="P5537_10295"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HRV78472.1"
                     /translation="MSHRLDFIVPGDPAQRTGGYLYDARIVEELRRLGWTVDVHGLPG
                     RFPDADPTARDALHATLAALPAGRRVVIDGLALGGLPEVAIEHAGRLPLVALVHHPLA
                     DERGLDPVLRRCLLASERAALAAVRMAITTSAFTARRLLDFGVRAERIRWVEPGTAPL
                     PLSAADGEPPHLLCVASLTPRKGQDVLVRALERVRALPWQCTLIGSASRDPGYADEIA
                     GLVRRAGLEDRIRLAGECADAALLEAYAAADLFVLPSHYEGYGMVVAEAIAAGLPVLA
                     TSGGALAATLPPGAGVHVPPGDVDALAGTLAELIGDRSRRLCLRDGARLARASLRSWT
                     QAGEAFAAALAALAPAPAA"
     gene            10394..11335
                     /locus_tag="P5537_10300"
     CDS             10394..11335
                     /locus_tag="P5537_10300"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HRV78473.1"
                     /translation="MQSRPDTAMPHPDACFDADWLALRAAADRAARAPRLETLAAAWL
                     RGRQQQNPQAPLRLVDLGCGSGANPRHLAPRLPGPQQWTLLDHDAGLLRRARTLCADL
                     RDAGGVRLQVDTRCLDLSALAASSLANADLVCASALLDLMSADWLGRLADACAHNGCA
                     LLITLSVDGTWRFLPQAPGAPADPDDAFIRDAFNAHQRRDKGLGAALGPAAAPALAEL
                     LVARGFAVERAASPWRLELADPAQAALARALIDGWRDAATAQCPQAAARINAWHQRRS
                     AQCDGRGSGQLEVGHLDLFACPPTTALRPDRPASPGQ"
     gene            11332..12312
                     /locus_tag="P5537_10305"
     CDS             11332..12312
                     /locus_tag="P5537_10305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysylphosphatidylglycerol synthase transmembrane
                     domain-containing protein"
                     /protein_id="HRV78474.1"
                     /translation="MSTEPRRTRRLLPILRALASLALLAGVLWWIDPRALAAAFAAPA
                     PGWLALALVIGVLQTALSAWRWRLTATRLGVPLGFGHALREYYLASFLNQVLPGGVMG
                     DAARAWRHGRLPGTASAAAWQAVVIERGSGQLALLLVVIASVLASPTVQAVPARLAEA
                     VDARGLPWVGTLAALVLVATALARRAREVLRSLARALGLALLARAVLLRQLLASLLIV
                     ASYVAVWLCCMRMIGLVTPPAQAAALVPWVLLAMAIPLSVGGWGIREGAAALVWQAAG
                     LDAAEGVAASVCYGLVVLLSTLPGAFVLQRHKPDARSAPEATPTCRADGP"
     gene            complement(12287..13123)
                     /locus_tag="P5537_10310"
     CDS             complement(12287..13123)
                     /locus_tag="P5537_10310"
                     /inference="COORDINATES: protein motif:HMM:NF024242.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HRV78475.1"
                     /translation="MSRPASVQHLDLCRLAAEIASDEAPLNAGEQYEALVLVSGRAFL
                     RTGEGEAEIELEPGQILLGTSAVPELRYSSDSELWSVLVPESILREACSECGWLQLAE
                     CVRFNRSPCSRDELDHLITLLRLVASEGASGAVRAQLFMHYAHAIANKLLFTLQRNQP
                     TSQICGQVRLFERLERHIEARIQQDISVEQLAQFAGLSQRSLYQVFKDQARMSPRSYI
                     RRKKLEHVYATLMDPAVRVASVTAVALDYGFTHLGRFAELYKSSFGVLPSESLKARPP
                     GK"
     gene            complement(13360..14289)
                     /locus_tag="P5537_10315"
     CDS             complement(13360..14289)
                     /locus_tag="P5537_10315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RibD family protein"
                     /protein_id="HRV78476.1"
                     /translation="MADELVPDWGWACILQARDADWAGAGAISFTVEGVSVEIAPGGA
                     WKCAHALRADTAALLDLFLPWVATPGRLAIAQLGQSLDGRIATASGASHYINCLEART
                     HLHRLRALVDAVVVGVGTVNADNPLLTVRHVAGRNPVRVVLDPRGRARAEANLFHDGA
                     APTVHLLGEDLAPACARLPDRLVRVGLPRTESGFAPAAVLEWLAGAGCRRVLVEGGGL
                     TVSRFVQAGAIDRLHLLVAPLLIGSGRPGLVLPPIDALDEALRPVCRQFRCGGDTLFD
                     LDFDGAHGRFQQVKSRETRNVTTKHFNLDKRML"
     gene            14387..15544
                     /locus_tag="P5537_10320"
     CDS             14387..15544
                     /locus_tag="P5537_10320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase II"
                     /protein_id="HRV78477.1"
                     /translation="MRQAERALFDLRRGLSILMRDHERAFVVCAVEGLVDAAAGAMQA
                     LAGSPARLVLSKHRLAAIGHPSAAPAVAIALSPLPDAAGLRALAWQRGASLPAGANLR
                     DGGLVESAALRLLGRAQLVPAALVCEVGAEQTAAIAAAVASGDLLAVDAAEAMRLCES
                     GPGRLARISEARVPLAEAENSRFVLFREADGVHEHVAIVIGERAGWPEDVPVRLHSSC
                     LTGDLFGSLRCDCGEQLRRGVAAIHALGGGVLLYLSQEGRGIGLANKLRAYGLQDEGL
                     DTIDADQVIGFSKDERDFRIAHEMLDELGIDRILLLTNNPSKVAALQKAGIHVVGRRA
                     IYGEVTEQNQRYLKTKASRHGHWLNDLLNEQGEPGDDEPACLPAADAAHRA"
     gene            complement(15577..16407)
                     /locus_tag="P5537_10325"
     CDS             complement(15577..16407)
                     /locus_tag="P5537_10325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="creatininase family protein"
                     /protein_id="HRV78478.1"
                     /translation="MNLTPALPWWQDLTPSRIAALARADAVVLLPLAAIEQHGEHLPL
                     STDLDIALGLLEAAVPKLRPGLPLCVLPPFVPGCSLEHSGFAGTLALGASTALASLVE
                     IGAGVARAGVRRLVLFNTHGGNKALVDLAALELRAAQRMLVVRAHSFRFPPPPDALPA
                     EELRHGLHGGALETALMLHLAPHKVRREAIDRFESIGVRMAAEGRVLGPEGEAGFAWM
                     AQDLHPSGACGDPRLADAALGERLVEHFATRLARIIEDARDFDLEGLVERSPPPDHRG
                     "
     gene            16581..>17705
                     /locus_tag="P5537_10330"
     CDS             16581..>17705
                     /locus_tag="P5537_10330"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78479.1"
                     /translation="MRTLVLGRLVPLFVPLFVLNALLVFGNAWPTLWPRPALAVSIEL
                     AFAVAALVLLAGWRGRIPPGLVRVLAALATLWIVLRYVQVTVPALFGRPLNLYWDLPH
                     LGAVLDMGGDGPGAKILLALALGALVVLALYGVVSACVRALAHGAAEAGARALLGGVA
                     GAAILLWALAPWVGPAPSSVTSSAFARPVAPLALEQIRFLSAALAADAADRLGADPDF
                     RGDLAALRGADVLILFAEAYGAVTFDRPPIAAALTDAREQLATAIATSGRRAVSGRVV
                     SPTFGGASWLAHAAVLAGVDTRDPADYALLLTTDRPTLVRHFAAHGYRTVGWMPGLQR
                     PWPEGRFYGFDRIADADSTGYAGLPFGFWRIPDQASMARIH"
BASE COUNT         2431 a         6621 c         5948 g         2605 t
ORIGIN      
        1 catcatcggc acgccggtgg tgacgttcgg ctcgccgaag gggccgtagc tgtggatcgc
       61 ggtgctggtg cccgcgctgt tggccgtgcc gatgatgctg cccaggtgat cggcgtagag
      121 ccagctcttg ttggtcgtcg tgctgccttc gtaccacacc agcggttcat ccacgccggg
      181 gccgtgcacg tagcggcgca ggagcgtgcc cgcgccgtcg tactcggcca ccagatcgac
      241 gccgtcgtag gcgagatcgg tgatcgcgcc ggccagcgtg gtgcggcgca gccggccttc
      301 ggcgtcgtag gcgagcgtgg cggcgtagcc cgtcttggtc gcgctcttga gcttgttgtc
      361 ggcgtcgaag gtgtaggtcc acaccccgtc gccggtcagg ttgccccggg cgtcgtgggt
      421 gagcgtggca ccggccgcgg cggtgtattg gttcaggccg ttggcggtgt agctctgggt
      481 gccgttggcg tagcccgtcc attggtacag gtcgttggtc cagttctggc ccacgatctc
      541 ctgcacttgg ttgcgggtgt aagcggtggt ctggtcctgc gcggtgccgg tcaggttgtg
      601 ggtgaggctc gcgagcacgc cttgggtgac gtagaagggg ccagttcacg aaacggaaaa
      661 atcgtatggt agtggcgtgg ccctgtacgg caatctgccg tataattgca acaggaggac
      721 aagactatgc ccgcagccac ttctaccgcc cgcctcgaag cccggatcag caccgatctg
      781 cattcgatgc tcaagcgcgc cgctgaactt caggggcgca ccatgactga tttcgtggtc
      841 gcggctgtcc aggacgccgc gcaacgcgcc atcgagcaag ccgaggtcat ccgcctgtcg
      901 ttggccgatc aggagtgctt tgcacaagcg ttgctgtcac cgccgcaacc ggccccggcc
      961 ttggaacgcg ctttcgcccg tcgccgcaag ctcttgcgtg ctgaatgagc agcgcaccgt
     1021 tccggctcac gccgctcgat gccgcgcatg ctcgcgcagc gttcaactgc ggttcagaac
     1081 cgcttgagcg ctacctgcgg gaacaagtca cccaagatgt tcgccgccgt gtggctgcct
     1141 gcttcgtggc gttggcggaa gggcagcgca tcgcgggcta ctacacgctg gcgtcggcaa
     1201 gcctgctgct ggccgatctt ccggccagcg tcggcaagaa gctgccgcgc tatccgaccg
     1261 tcccagcggt tcgcatgggc cgcttggccg tcgatcaggc tttcaaaggg caagggctgg
     1321 gcggcgcact gctggccgat gcgcttgacc gtgctgtccg ttccgaaatt gccgcctatg
     1381 ccttgatggt ggatgccaag gacgaggcgg cagcggcctt ctaccgacat catggcttca
     1441 tcgctttgcc cgactcaccg ttcacgctct tcctgccgct ggcaacgctg gaggcgtctc
     1501 ggaaaacgga aaatagagcg cgctaagccg gtggcattcg tatgcgtcag gctgggcgat
     1561 aggctaaccg ggcgtcaggc tgcccggcgc tcatgcgtca ggacagagtc taattgcgca
     1621 tcgattgaca tatcccgcca agggtcctac ctgcgctttc ccggcatcat acttggcgtc
     1681 gatgaaccgc cgttcccgcc attgctgaaa ctaatcgccg accagctcaa ggtcggcgtc
     1741 gaaagctagg acggttatgg ggagcgggag cagacccggc gcgagcactt gatcgagctg
     1801 caaacggtat tcggctttca gacctttacg atgaggcact gccgcaggcg gcacatacgc
     1861 tgaccgaatt ggccatgcaa accgacaagg gcgtcgtgct cgtcgatgct ctgatcgccc
     1921 gccctgcacc gcccccggga gccaccatga agctgcgcct cgccctgctg atcctcgtcc
     1981 tcgccgccct cctcgcctcg ggcatcgccc cctacgaccg cggcgtgtgg tgggccgagg
     2041 tggccccggt actgatcgcg ctgccgatcc tgctcgcgag cgcgcggcgc ttcccgctca
     2101 ccccgctcac gtatggcctg atcgcgttct tctcgctgat cctgatcctc ggcggcgcct
     2161 acacctacgc acgggtgccg gtcggcttcg tggtgcagga ctggttcgag ctcgcgcgca
     2221 acccttacga ccgcttcggc cacttcttcc agggcgtcac cccggccatc ctcggtcgtg
     2281 agctgttgct gcgcacctcg ccgctgcgcc cgggaaaatg gctgttcgcc ctgcttaccc
     2341 tgagctgcac cggcatcagc gcgctctacg agttggtcga atgggcctcg gccgagctgt
     2401 gggccggcgg cgcggtggag ttcctcggca cccagggcga cccctgggac gcccagtccg
     2461 acatgctgat ggcgctgctc ggagcgatca tcgcgcagat cgtgttcgga cggctgcacg
     2521 accgccagct cgcgcgcctc gccgcgcagc catccacctg aacggacgca tccggccgat
     2581 cttcatatcg gccgtccgtc tcggcgactt gggtcgccgg ccaccgccgg cccctcgccc
     2641 ccggcccatc tagccccggc ggcatcccgc accgggcgcg cgacctcccc cgaaaggcga
     2701 gcctgatgcc tcgccccgac tcggctcagc ccgctctacg aggacctgtt ctcgtaagcc
     2761 gactttttac aaccagctca gtctcgccgt gcgctgaccg ggtccgttac tggcgtgcgc
     2821 ggtcgcagcc agcctccaag ccccgccgag cgaccgggga ggatctgtgg cggagcacct
     2881 cccgctcccg gccgcaagcc ctcacacccc atgccgccgg cggtgctggc gggcgccggc
     2941 ggcgccctcg gcgtccgagt aggcgtggcg cgctgcggtc atctcggcga gcacggtggc
     3001 gatcttgtgg ttgagcgtgc ccttggggat cacgcccttg gcgtcgggct cgccggcctc
     3061 gacgccggtc agcaccgtca tcgcctcgtc caccgtcttc acggcgtgga tgtggaagcg
     3121 cccttccgcc gcagcctgca ccacgtcctc gcgcagcatc aggtggcgca cgctcgccgc
     3181 cggaatcacc acgccctgcg tgccgtccag gccgcgcgcg ctgcacaggt cgaagaagcc
     3241 ctcgatcttc tcgttcacgc cgccgatgac ctgcacctcg ccgaactggt tcaccgaacc
     3301 ggtgatcgcg aagcgctgct ggatcggcac ctgggtcagc gccgacagca gcgcgcacag
     3361 ctcggcgagc gaggccgagt cgccctcgac cggcgcgtag gactgctcga acaccaggct
     3421 cgccgacagc gacagcggct ggtggcgtgc gtagcgcgcg gcgaggaagg ccgacaggat
     3481 cagcacgccc ttggagtgga tcgcgccgcc gagctcggtc tcgcgctcga tgtcgaccac
     3541 gtcgccctcg cccatgcgca ccgtggcggt gatgcgcacc gggtggccga agtgctcgcc
     3601 ggcgagctcg atcaccacca ggccgttgat ctgcccggcg cgctcgccgg tggtggagat
     3661 cagcgtggtg ccgtcgagga tcgactccag cacgcgggtc gggtagcggt tggcgcgccg
     3721 agcgcgggcg gcgagcgcgt cctcgacctc ggcacgcgtc gtggcggcaa ggcccttctg
     3781 gcgggcgtgg aagtcggcct cgcgcatcag gtcggagagc gcgcgggtgt tgagcgacag
     3841 gcgccccgag tcctcggcca ggcgcgaggc ctcctcgacc aggcgcgcca cgccgctgcg
     3901 ctcgaccgcc agcagcttcg cgccgcgtgc gagcagcgcc atcaggcggg cgtactcgca
     3961 ctcgttctcg ggcgtgcgca ggatgtcgtc gttgaagtcg gccgcgacct tgaagaggtc
     4021 ggcgaactcc gggtcgtgct ccatcaacag gtagtagacc tcgcggtcgc cgatcagcac
     4081 caccttgagc gcgctcggca ccgcctcggg ctccagggtc agcgctccgc tccagccctg
     4141 cgcctcggcc ggcggctcga tgcggatctc gcccgcgcgc aggctgcgct tgaggccttc
     4201 ccaggcgaag ggctgcgaca gcaggcgctc ggcgtcgagc accaggtagc cgccgttggc
     4261 gcggtgcagc gcgccggcgc ggatcaggtt gaagtggctg acctgattgc cctgctgcac
     4321 gatgtgctcg atgcggccga tcaggttgcc gtagccggga ttgttctcga acaccaccgg
     4381 cgcgccctgc gagccggagt gatcgaccag cagcttgacc tgatagcggt gatagcgggt
     4441 gttctcctcg ggctcgggag cctcgtcgtc ctcctcgtcg agcatggtgc cgcgcaccgc
     4501 actgtcgatg acgtcacgct ccaccgcatc gaggaaggcg agcacggccg gcaggtcctc
     4561 gtgcgcgtcg cgcacctcgc gcagcaggtg agccaccgcg gggccaagca cctcgcgctc
     4621 ggcgcggtcg atcgactcgc gcaccgactt gcgccagccg gnnnnnnnnn nnnnnnnnnn
     4681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4741 nnnnnnnnnn nnnnnnnnnn ncaggcgcga aggcggcggt gcggtcctgc acgcgcgtcg
     4801 tttgccaggc cgacggcttc gcagctgccg cagctcctac aggcggggcc ggagcagtgt
     4861 ggtggtttgt gtaggagcgc cggcaggcgc gaacgcggcg ccggaatccc gcgcgcgcgt
     4921 cgcaggatgc gaaacccacc cgtgcgaacc tcgccttgca ccgcgctgtc cacgaatcga
     4981 taatcccgca actcgaaccc cagcccgcag ccgcagccga ccatgaaagt catcccgatc
     5041 cagcaggccg cgtccccgct cgcccccgcc gacccagcgc ttgtcccggc gcccggcgcc
     5101 gcgctcgtcg accgacgcgc acgcaacgtg cgcgacctgc gcatctcggt caccgatcgc
     5161 tgcaacttcc gctgcgtgta ctgcatgccg cgcgaggtct tcggcgacga ctacgccttc
     5221 ctgccgcggc ggcagctgct cagcttcgag gagatcctgc gcgtggcgcg gctgttcgcc
     5281 gcacgcgggg tgcgcaagat ccgcatcacc ggcggcgagc cgctgctgcg caaggacgtc
     5341 gaccgcctga tcggcatgct cgccacgctc gacggcgtcg agatcaccct caccacgaac
     5401 ggcgtgctgc tgcccaagct cgcgcgccgg ctcaaggacg ccggcctgca ccgcgtcacc
     5461 gtgagcctgg atgcgctcga cgacgccctg ttccggcgca tgaacgacgc cgactacccg
     5521 gtcgacaagg tgctcgaggg catcgaggcg gccagggcgg tcggcctggg cccgatcaag
     5581 gtcaacatgg tggtcaagcg cggcaccaac gattccgaca tcgagccgat ggccgcgcac
     5641 ttccgcaaca gcggccacat cctgcgcttc atcgagttca tggacgtggg cgcctccaac
     5701 ggctggaaga tggacgaggt gctgccctcg cgcgaggtcg tcgcccgcat cgaccgcctc
     5761 ttcccgctcg aaccggtcga ccccaactac gagggcgagg tcgccgagcg ctggcgctac
     5821 aaggacggtg ccggcgagat cggggtgatc tcttcggtca cgcaggcctt ctgctcgagc
     5881 tgcacccgca tccgcctgtc caccgaaggc cagctctaca cctgcctgtt cgcccagcag
     5941 gggcacgacc tgcgcgcgct gctgcgcgag ggtgccgacg acgcccgcat cgacgccgcg
     6001 atcgcgcagg tgtggcaggg gcgcgaggac cgctactccg agatccgcac cgccgagacc
     6061 gccgcgctgc gcaagatcga gatgtcctac atcggcggct gaagcggccg ccgatgcagg
     6121 ctccgccgcc agcgcctcaa tcgtcgcgca tcgcctccag ctcgaagcgc agttccaccg
     6181 catcgcccac catgccgcgg ctgatgccgt agtccatgcc ccagcggctg cgctcgatgg
     6241 tcgtgcgcgc cgagatgccg agcgtgtgct tgcggtggcc gaagggatag gtcgcggcct
     6301 tgttcagcgt cacgtcgagc accaccggat gggtctgccc gagcagggtc aggcgcccgg
     6361 cgagcctgcc ctccaggcgc ccgtcacgct ccccgcccgg ctcgaaggcg gtggcctcga
     6421 agacgatctc gggatgcttc ttggcgtcga ggaagtcgct gtcgcgcacg tggcgatcgc
     6481 gcgcctcgtg gttgctgaac acgctgtcgg ctgccaccac cacccgaccc gacttcagcg
     6541 tgcgtgcagc ctcgtcgtac tcgaagcgtc cgctcgcctt gaggaacatg ccgatgatgt
     6601 ccgcgtagcc gatgtggtcg acctggaagc cgatggcgaa atgatcgggg tcgatcgtat
     6661 agctgcgcgg ctccgcccac gccggggcgg cgccgagcac gcccgcgagc gcggtcgcgg
     6721 cgagcgtgcg ggaaatacat ctgcgcgatt ccatcttgct tcctcctcca ggggtttgcg
     6781 ggccgggcac ccatagcgcg acgacaaatg ccggcgctcg aacgccgcgt gtggacgctt
     6841 gggcagcgcg cgcgcgctca ggttcgcggg cggctgcggt acagccagcg cacatcgacc
     6901 gcgaaggacc acgccagcag cgccagcgcc agcgccagca gcatcgtcgc cagcgcgcca
     6961 gcgatcaccg gcagcaggca caccagcagg ctcgcgacct gccacacgca caccagcttg
     7021 cgccgccggc tctccggcag cggccgctcc agccagggcc agggctgcat cgcggcgacg
     7081 aaggcatagc gcatcgcccc gatcgccagc acccagggcc ctgccttgcc catcgccagc
     7141 agatgcacgc acaggaccag gatcaggaag gcgtcgagct ccatgtcgaa gcgcgcgccg
     7201 aagtcgctct cgcaatgcca gcgccgcgct acccagccat ccacgccgtc gagcagcagg
     7261 gcgatcgcgg cgagcactgc gaccgccacg gcgtgctcgc ccacccatcc cggcgctgcg
     7321 agcgcgccgg caagcgcggc caccagcagc gcgcgcccga gcgtgacgca gttggccgga
     7381 ccgagcccgc cgcgcgattc gcgccggaag cggaggatca gcgcggagat ggcgagcaag
     7441 acggcgcccg ccgcccatgc ggcgccagcc ggcaacgcca gcgtagtgat cgccagcgcg
     7501 aggagcgcga cgaggccgcc aaagccgccg gccagttcca gccagaggcg gggaagtccg
     7561 ccgcgccgaa cgcaagatcc gccctgctcc atcgccttca tgtcccttcg tccgtcacgc
     7621 acgccgctct cagcgccgca ggagcggcgt cggccgcgaa tcgggtcgca cggatctcga
     7681 cgcgcatgct gccgatccac ggccacatcc gcgcctgccg gcgcgcctac aggggctgcg
     7741 gcgccctgct accatgcctg cttcgatcat ccgctgcgcg aaagggttcg cacaaggagc
     7801 gccgcatgtc cgcccccaac ctcgccttct ggaccgtccg cccgggctgc ggcgaactgc
     7861 gcccggcgcc gctgccgccg cccggcgcgg gcgaggtcct cgtgcgcaac ctctacggcg
     7921 cagtcagccg cggcaccgag ggcctggtct ttcgcggcga ggtgcccgag agcgaatacc
     7981 agcgcatgcg cgcacccttt caggaaggcg atttccccgg tccgctcaag tacggctaca
     8041 tcggcgtcgg cgtggtggag gacggtgtcg gcgacgccgc cgccgcactg cgcggccgca
     8101 cggtgttctg cctgcacccg caccagcagc gctacgtggt gcccgccgac gccgtcgttc
     8161 ccttgcccga aggcgtgccc gccgcgcgcg cggtgctggc cgccaacctc gagaccgcga
     8221 tcaacgcctg ctgggacggc gctcctgcgg tgggcgaccg cgtcgcggtg gtcggcgccg
     8281 gcgtgctcgg cagcctggtc gcctggctgt gcgcgcgcat ccccggcgtc gagctcgaac
     8341 tgatcgacac cgatccaggc cgcgcacgcc ttgccgaggc gctcggcctg gttcaccgcc
     8401 tgccggacca ggcccgcggc gactgcgacc tcgtcttcca cgccagcggc aaccccgccg
     8461 gcctggtgcg cgcgctcgag ctcgccggcc aggacgccac cgtgatggag atgagctggt
     8521 acggtcgccg cagtgccgag ctgccgcttg gcgccgcctt ccacgcgcgc cgcctgcgcc
     8581 tgcagtccag ccaggtcggc cgcctgccgc cgcagcgcag cccgcgctgg gattaccgcc
     8641 gccgcatgga actcgcgctc gccctgctcg tcgatccacg gatggacgcg ctgatcagcg
     8701 gcgagaccga cttcaccgaa ctgcccgcgc tgatgcagcg cctcgccgac gctcccgccg
     8761 gggcgctgtg cgagcgcatc cgctatgacg gtcccacccc ctgagatcca acccagcatc
     8821 gatccggagc ccccatgtac agcctcaccg tccgcgaaca catcatgatc gcccacagct
     8881 tccgcggcga gatcttcggc ccggcgcaga agatgcacgg cgcgacctac ctggtcgatg
     8941 cctgcttcca gcgcagcgag ctcgacgccg acggcctggt ggtcgacatc ggcctcgccg
     9001 ccgagacgct gaaggcggtg ctcgccgagt tcaacttccg caacctcgac gagctcgagg
     9061 agttccgtgg ccgcaacacc accaccgagt tcatggccag ggtggtcttc gaccgcctcg
     9121 cggcggcgat ccgcgccggc cgcatcggcc ccggggcaaa ggggctcgag cggctgaagg
     9181 tgagcctgca cgagtcgcac gtcgcctggg cgagctacga gggcacgctg tgagcggaca
     9241 ccatctcgcc gcccgcggcg gcggttcgcg ccgcgcaggg ccctgtcgcc ggcgcggcgg
     9301 accagggcac acgcgatgag ccaccggctc gatttcatcg tccccggcga ccccgcccaa
     9361 cgcactggcg gctatctcta cgatgcccgc atcgtcgagg aactgcgccg cctcggctgg
     9421 acggtcgacg tccatggcct gcccggacgc ttccccgacg ccgaccccac ggcgcgcgac
     9481 gccctgcacg ccaccctcgc cgcactgccc gccggccggc gcgtggtgat cgatgggctc
     9541 gcgctcggcg gcctgcccga ggtcgcgatc gagcatgccg ggcggctacc gctggtcgcc
     9601 ctggtccacc acccgctggc cgacgaacgc ggcctcgacc cggtgttgcg gcgctgcctg
     9661 ctggcgagcg aacgcgccgc gctcgccgcc gtgcgcatgg cgatcaccac cagcgccttc
     9721 accgcgcgcc ggctgctcga cttcggcgtg cgcgccgagc gcatccgctg ggtcgagccg
     9781 ggcacggcac cgctgccact ctccgccgcg gacggtgaac cgccccacct gctgtgcgtc
     9841 gccagcctca ccccgcgcaa gggccaggac gtgctcgtgc gcgcgctcga acgcgtgcgc
     9901 gcgctgccct ggcagtgcac gctgatcggc agcgccagcc gcgaccccgg ctacgccgac
     9961 gagattgccg ggctcgtccg ccgcgccggc ctggaggacc gcatccggct cgccggcgaa
    10021 tgcgcggacg cagccctgct cgaagcctac gctgccgccg atctcttcgt gctgccctcg
    10081 cactacgagg gctacggcat ggtggtcgcc gaggcgatcg ccgccgggct gccggtgctc
    10141 gccaccagcg gcggcgcgct cgccgccacc ctgccacccg gcgccggggt gcacgtcccg
    10201 cccggcgacg tcgatgcgct cgccgggacg ctcgccgagc tgatcggcga ccgcagccgg
    10261 cgcctgtgcc tgcgcgacgg cgcccgcctc gcccgcgcca gcctgcgcag ctggacgcag
    10321 gctggcgagg ctttcgccgc cgccctcgcc gcgctcgcgc cggcacccgc agcgtgatcc
    10381 ccccggaacc gacatgcagt cccgccccga caccgccatg ccccaccccg acgcctgttt
    10441 cgatgcagac tggctcgccc tgcgcgccgc cgccgaccgc gctgcgcggg caccccggct
    10501 ggagaccctc gccgccgcct ggctgcgtgg ccggcagcag cagaacccgc aggccccgct
    10561 ccgcctggtc gacctcggct gcggcagcgg tgccaacccg cgccacctgg cgccacgcct
    10621 gcccggtccg cagcagtgga cgctgctcga ccacgacgcc ggtcttctgc ggcgcgcccg
    10681 caccctctgc gcggacctgc gcgacgccgg gggcgtgagg ctgcaggttg acacccgctg
    10741 cttggatctg agcgcactcg ccgcgtcttc gctggcgaac gctgacctcg tgtgcgcctc
    10801 cgccctgctc gacctgatgt cggcagactg gctggggcgc ctcgccgatg catgcgcgca
    10861 caacggctgt gcgctgctga tcacgctgag cgtcgacggc acctggcgct tcctgcccca
    10921 ggctcccggg gcgcccgcag accccgacga cgccttcatc cgcgatgcct tcaacgccca
    10981 ccagcgccgc gacaagggcc tcggtgccgc gctcggcccg gccgccgcgc ccgcactcgc
    11041 cgagctgctc gtggcgcgcg gcttcgcggt cgagcgcgcc gccagcccgt ggcggctgga
    11101 gctcgccgac cccgcacagg ccgcgctcgc gcgcgcgctc atcgacggct ggcgcgacgc
    11161 cgcgacggcg cagtgcccgc aagccgccgc gcgcatcaat gcctggcacc agcgccgcag
    11221 cgcgcagtgc gacggcaggg ggagcgggca gctcgaagtc ggccatctcg acctcttcgc
    11281 ctgcccgccg accaccgccc tgcgccccga ccgccccgcc tctcctgggc aatgagcacc
    11341 gaaccccggc gcacgcggcg cctgctgccc atcctgcgcg cgcttgcgag cctggccctg
    11401 ctcgccggcg tgctgtggtg gatcgacccg cgtgccctcg ccgccgcctt cgccgcaccc
    11461 gcacccggat ggctggcgct cgcgctcgtg atcggcgtgc tgcagaccgc cttgtcggca
    11521 tggcgctggc ggctcaccgc cacccgcctc ggcgtaccgc tcggcttcgg ccacgcgctg
    11581 cgcgagtact acctggcgag ctttctcaac caggtcctgc ccggtggcgt gatgggcgac
    11641 gccgcgcgcg cctggcgcca cggccgtctg ccgggtacgg ccagcgccgc ggcctggcag
    11701 gcggtggtga tcgagcgcgg ctcgggccag ctcgcgctgc tgctggtggt gatcgcgagc
    11761 gtgctcgcct cccccaccgt gcaggctgtg ccggcacgcc tggcagaagc cgtcgacgcc
    11821 cgagggctgc cttgggtggg cacgctcgcc gcgctggtgc tcgtcgcgac ggcgctcgca
    11881 cgccgcgccc gggaggtcct gcgcagcctg gcccgcgccc ttgggctggc gctcctcgcg
    11941 cgcgcagtgc tgctgcgcca gctgctcgcc tcgctgctga tcgtggccag ctacgtcgcg
    12001 gtgtggctgt gctgcatgcg catgatcggc ctcgtcacgc caccggcgca ggccgccgcg
    12061 ctggtgccct gggtgctgct ggcgatggcg atcccgctgt cggtgggagg ctggggcatc
    12121 cgcgaagggg ctgcagcgct ggtgtggcag gctgccgggc tggacgccgc cgaaggtgtg
    12181 gcggcgtccg tgtgttatgg gctggtcgtg ctgctgtcga ccctgccggg tgcgttcgtg
    12241 ctgcaacgcc acaagcccga tgcgcgatcc gcccccgagg caacgcctac ttgccgggcg
    12301 gacgggcctt gaggctctcc gagggcagga cgccgaagct cgacttgtag agctcggcga
    12361 aacggccgag atgggtgaag ccgtagtcga gcgccacggc cgtcacgctc gccacgcgca
    12421 cggcagggtc catcaaggtc gcgtacacgt gctcgagctt cttgcgtcgg atgtagctgc
    12481 gcggcgacat ccgcgcctgg tccttgaata cctggtagag cgagcgctgg ctcaacccgg
    12541 cgaactgggc gagctgctcg acgctgatgt cctgctggat gcgcgcctcg atgtgccgct
    12601 cgaggcgctc gaacagccgc acctggccac agatctgcga ggtcggctgg ttgcgctgca
    12661 gggtgaacag cagcttgttg gcgatagcat gggcgtagtg catgaaaagc tgcgcgcgca
    12721 ccgccccgct ggcaccttca ctcgcaacca ggcgcagcag cgtgatcaga tgatcgagct
    12781 cgtcgcgcga gcaagggctg cgattgaaac gcacgcactc ggccagctgg agccagccgc
    12841 actccgaaca cgcctcgcgc aggatcgact cggggacgag cacgctccac agctcgctgt
    12901 cggacgaata gcgcagctcg ggaactgcac tggtaccgag taggatctgg ccgggttcga
    12961 gctcgatctc ggcctcgccc tcgccagtgc gcaggaaggc acgcccactc accagcacca
    13021 gcgcctcgta ctgctcgccc gcgttcagcg gcgcctcgtc cgacgcaatc tcggcggcga
    13081 gccggcacag gtcgaggtgc tggacgctcg caggccgtga cactccccca agctgggaga
    13141 ccggctctcg cccggccgca cgctcgattg cggcaatcgg cgccggggca tgcggtcgtt
    13201 gcgaattgga cgacaggtcg atcggcatcc tcactccagt gaatcggcga gccggctgaa
    13261 gcgtgcaccc gtcgcccact cgccgcggag cgccggtcgt ctcgcggcgg cgccgaacga
    13321 ctcagcgtcg cacggaaacg gttacgaaaa cgtgattcat tatagcatcc gtttgtcgag
    13381 gttgaagtgt tttgtcgtta catttctagt ttctcgagat tttacttgct gaaaccgtcc
    13441 gtgtgcgcca tcgaagtcga gatcgaacaa ggtgtcgccg ccgcagcgga actgcctgca
    13501 caccgggcgc agcgcctcgt cgagcgcgtc gatcggcggc agcaccagcc ctggccgccc
    13561 cgaaccgatc agcagcggcg cgaccagcag gtgcagccga tcgatcgctc ccgcctgcac
    13621 gaagcgcgac accgtgagtc cgcccccctc cacgagcacc cgcctgcatc ccgcgccagc
    13681 cagccattcc agcaccgcag ccggcgcgaa ccctgactcc gtccgcggca ggcccacgcg
    13741 gacgagccga tccgggagcc tcgcgcaggc cggcgccaga tcctcgccaa gcagatgcac
    13801 cgtcggcgct gcaccgtcgt ggaacagatt cgcctccgcc cgcgcccgcc cgcgcgggtc
    13861 gagcaccacg cgcaccgggt tgcgcccggc cacgtggcgc accgtcagca gtggattgtc
    13921 ggcattcacc gtgcccaccc ccaccaccac cgcatccacc agcgcccgca gccggtgcag
    13981 gtgagtgcgc gcctcgaggc agttgatgta gtgcgaggcc ccgctcgcgg tggcgatgcg
    14041 cccatccagg ctctgcccca gctgggcgat cgcgagccgg cccggcgtgg ccacccaggg
    14101 caggaagaga tcgagcagcg ccgcggtgtc ggcgcgcaag gcgtgcgcgc acttccaggc
    14161 ccccccgggc gcgatctcga cgctcacgcc ctcgaccgtg aaacttatcg cgccggcgcc
    14221 ggcccaatcc gcatcacggg cttgcaggat gcaggcccag ccccaatctg gtacaagttc
    14281 gtccgccatc catccttcct tgaaaaatcg tcttcactcg cgtctgccgg cctgcaaagc
    14341 gcctggtgca gggtcgagcc ccgacacccc aaacggagaa aaacaaatgc gccaagccga
    14401 gcgtgccctc ttcgacctgc gccgcggact ttcgatcctc atgcgcgacc acgagcgcgc
    14461 cttcgtcgtg tgcgcggtcg aaggcctggt cgatgccgcc gcgggcgcga tgcaggcgct
    14521 ggccggctcg cccgctcgcc tggtgctgag caagcaccgc ctcgccgcga tcggccaccc
    14581 cagcgccgca ccagccgttg caatcgccct ctcgcctctt cccgacgctg ccggactgcg
    14641 cgcgctcgcc tggcaacgcg gcgccagcct gcccgccggc gccaatctac gcgacggcgg
    14701 cctggtcgaa agtgccgccc tgcgcctgct cggccgcgca cagctggttc cggcggcgct
    14761 ggtctgcgaa gtcggcgccg agcagaccgc cgcgatcgct gccgcggtcg cgagcggcga
    14821 tctgctcgcg gtggacgcgg ccgaggccat gcgcctgtgc gagagcggcc cgggccggct
    14881 cgcccgcatc agcgaggcgc gcgtgccgct ggccgaggcc gagaacagcc gcttcgtgct
    14941 cttccgcgag gccgacggcg tgcacgagca cgtcgccatc gtgatcggcg agcgcgccgg
    15001 ctggcccgag gacgtcccgg tgcgactgca ctcgtcctgc ctcaccggcg atctcttcgg
    15061 cagcctgcgc tgcgactgcg gggagcagct gcgtcgcggc gttgcggcca tccacgcgct
    15121 cggcggcggc gtgctgctgt atctgtcgca agagggccgc ggcatcggcc tggccaacaa
    15181 gctgcgcgcc tacggcctgc aggacgaagg cctggacacg atcgacgccg accaggtgat
    15241 cggattctcc aaggacgagc gcgacttccg catcgcccac gagatgctcg acgagctcgg
    15301 catcgaccgc atcctgctgc tcaccaacaa cccgagcaag gtcgccgcgc tgcagaaggc
    15361 cggcatccac gtcgtcggcc ggcgcgcgat ctatggcgag gtcaccgagc agaaccagcg
    15421 ctatctcaag accaaggcca gccgccacgg gcactggctg aacgatctgc tcaacgagca
    15481 gggtgagccc ggtgacgacg agcccgcatg cctgcccgcc gcggacgccg cgcaccgcgc
    15541 ctgaggcgag gcctgccgcc cggcgatgct gcgcgctcag ccgcggtgat cgggcggcgg
    15601 actccgctcg acgagcccct ccagatcgaa gtcgcgtgca tcctcgatga tgcgcgcgag
    15661 cctagtcgcg aagtgttcca ccaggcgctc gccgagcgcg gcgtccgcca ggcgcggatc
    15721 gccgcaggca cccgacgggt gcaggtcctg tgccatccag gcgaagccgg cctcaccctc
    15781 ggggccgagc acgcgcccct cggccgccat gcgcaccccg atcgactcga agcgatcgat
    15841 cgcctcgcgc ctcaccttgt gcggcgccag atgcagcatc agcgcggtct cgagcgcccc
    15901 gccgtgcagg ccgtggcgca gctcttcggc cggcagcgcg tccggcggcg gcgggaagcg
    15961 gaaggagtgc gcgcgcacca ccagcatgcg ctgcgccgcg cgcagctcga gcgcggccag
    16021 atccaccagc gccttgttgc cgccatgggt gttgaacagc accagacggc gcacccccgc
    16081 ccgcgcgacg ccggcgccga tctccaccag gctcgccagc gcggtgctcg cgccgagcgc
    16141 gagcgtgccg gcaaagccgc tgtgttccag gctgcagccc ggcacgaagg gcggcagcac
    16201 gcacagcggc agccccgggc gcagcttcgg cacggcggcc tcgagcaggc cgagggcgat
    16261 gtcgaggtcg gtcgacagcg gcaggtgttc gccatgctgc tcgatcgcgg cgagcggcag
    16321 cagcacgacc gcatcggcgc gggcgagcgc ggcgatgcgg ctcggggtca ggtcctgcca
    16381 ccagggcagc gcgggcgtga ggttcatggc ggtcgggatc tcggcggggg gcgactgatc
    16441 cggatcatag ccgcagtcgg ggccagcccg tgggcgcagg gcgccgcagc ctggtgcccg
    16501 gcgcgtgcgg ggcgccggtc cgccacctcg cgccgcccgg cgcgtgccgc acgcagcgga
    16561 acgctcgcgt gagcgcacga atgcgcaccc tcgtcctcgg caggctcgtg ccactgttcg
    16621 tgccgctgtt cgtactcaac gccttgctgg tgttcggcaa cgcctggccg acgctgtggc
    16681 cgcggccggc gctggcggtc tcgatcgagc tcgccttcgc cgtcgccgca ctggtgctgc
    16741 tcgccggctg gcgcggacgt atcccacccg gcctcgtgcg cgtactcgca gcgctggcca
    16801 cgctgtggat cgtgctgcgc tacgtgcagg tcaccgtgcc cgcgctgttc ggccgcccgc
    16861 tcaacctcta ctgggacctg ccccaccttg gcgccgtcct cgacatgggc ggcgacggac
    16921 cgggcgcgaa gatcctgctc gcgctcgcgc tcggcgccct cgtcgtgctg gccctgtatg
    16981 gcgtggtgtc ggcctgcgtg cgcgcgctcg cgcacggcgc tgcggaagcg ggcgcgcggg
    17041 cgctgctcgg cggcgtggcg ggcgcggcga tcctgttgtg ggcgctggcg ccgtgggtcg
    17101 ggcccgcccc ctcatccgtc acctcatcgg ccttcgcgcg gccggtcgcc ccgctggccc
    17161 tcgagcagat ccgcttcctg agcgcggcac tcgccgccga cgccgccgac cggctcggcg
    17221 ccgaccccga cttccgcggc gacctcgcgg cgctgcgcgg cgccgacgtc ctgatcctgt
    17281 tcgccgaggc ctacggcgca gtcactttcg atcgaccacc gattgctgcg gcgctcaccg
    17341 acgcacgcga gcagctcgcc accgcgatcg ccaccagcgg ccgccgggcc gtctccggcc
    17401 gcgtggtctc gccgaccttc ggcggcgcct cctggctggc gcacgccgcc gtgctcgccg
    17461 gcgtcgacac ccgcgacccg gcggactacg cgctgctgct caccaccgac cgtcccaccc
    17521 tcgtccgcca cttcgccgcc cacggctacc gcaccgtcgg ctggatgccg ggactgcagc
    17581 gcccgtggcc ggagggccgc ttctacggtt tcgaccgcat cgccgacgcc gacagcacgg
    17641 gctacgccgg cctgcccttc ggcttctggc gcattcctga ccaggcctcg atggcgcgca
    17701 tccat
//
LOCUS       DAOTIN010000061        17505 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_3908_length_17505_cov_9.337192, whole genome shotgun sequence.
ACCESSION   DAOTIN010000061 DAOTIN010000000
VERSION     DAOTIN010000061.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 17505)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 17505)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17505
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3908_length_17505_cov_9.337192"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(19..2475)
                     /locus_tag="P5537_10335"
     CDS             complement(19..2475)
                     /locus_tag="P5537_10335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HRV78480.1"
                     /translation="MPPISFDLRPSSIRIRLLLASTVVQVVLLSLLLANSVRLMNNAM
                     SASLETTIGQTASMLHAMATAYGEQRRLDALEDVLGELLADADEGLLYVRIRDARDDL
                     LVSAGMPDLTHVPEPNEHRRRFFETLLADDLVHVRRQLLLARNEVGTLQFGVSVSVLA
                     AAREAIMQQGLAIAIAEILLTFVLLSSLGYLLTRNLRLLLEGSRAIASGFLDHRVESR
                     GKDELAVIADHFNVMAATLQNRIAELQDTAERLQASEERYALALRGSNDGLWDWDIDA
                     DDVYYSERFCQILGVEPGSLSSKPEDILAYLHPHEVEAYRQRLIDHLKGNSNHFIMEL
                     RARLPDGAYRWVLMRGVADRDEDLRAYRMAGSLGDIDLRKRAEQQLVHDALHDGLTGL
                     PNRAMFIEHANRALAQRRRGDLAQIAVLAINLERFSLVNDSYGHLVGDELLRRIGAHI
                     AALMRDGDVCARVGGDQFAVLLNGVENSIDALRICEQLVALPAFSPNGNGQQLHPRCR
                     VGVAISDNEREDAESLLRDADNALHKARRSDTGPIEFFQTEMHAAAVRALQVEAELRK
                     ALTQGGLQTWYQPIVELANRRPTGFEALVRWPHPTLGLLSPAEFIPLAEALDLIHDIG
                     MIVLERTCTDLQAWSSQLPFDAPLRVSVNLSARQLARPDLAAELLDVIDRSGVAHDRI
                     RFEVTESVLAHPDGPAIDHLHALRAAGIDILIDDFGTGYSTLSYLHTMPCNQVKLDGS
                     FVRSLPHDQRLRAIVRHSIELAHDLGMTVVAECIEDEAQLEILRAMGCDFGQGYLFSR
                     PLDGDATLRHLQSLHPEPGR"
     gene            complement(2483..3865)
                     /locus_tag="P5537_10340"
     CDS             complement(2483..3865)
                     /locus_tag="P5537_10340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonyl-CoA decarboxylase"
                     /protein_id="HRV78481.1"
                     /translation="MSGAGLVSRGLSRVRELVASAAHLGKAPDESDLERLRTQLQECA
                     EGRGGEVSTRQRAARLAETYLRLDDAGRHAFLRLIAHEFGPDPSRVAAAHAAYQAAIG
                     TAGQWDAEAELRTALRSRRLRILTQFNAIPQGVKFLVDLRADLLRFIADDPLLKPLDR
                     ELETRLSAWFDVGFLELQRITWSSPAALLEKLVEYEAVHEIRSWKDLKNRLDSDRRCY
                     AFFHPRMPLEPLIFVQVALLEEIADDVQRLLDIEAPLADAGRATTAIFYSISATQKGL
                     RGVSFGNFLLKRVIDDLKRDFPRLKTFATLSPIPGLVRWAQRDPEAFAEAFNATDWKR
                     LAALGVEGGDSPRLAALLAGDPAWVADEALALALREPLLRLGARYLSEARRGDRPVDS
                     VARFHLGNGARIERLNWLADRSDKGLRQSWGMMVNYLYDPDSLEANLENFAANGSIAA
                     SSAVRRLARR"
     gene            complement(3963..4784)
                     /gene="lgt"
                     /locus_tag="P5537_10345"
     CDS             complement(3963..4784)
                     /gene="lgt"
                     /locus_tag="P5537_10345"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004332537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HRV78482.1"
                     /translation="MLVHPQFDPIALSLGPLSVRWYGLMYLVAFVLFVVLGRRHARRR
                     PELGWDAQGIDDLLMYGVIGVILGGRLGEVLFFQPGYYLQHPGEILAVWKGGMSFHGG
                     FLGVLAAMWLYGRRHGKDFWQVTDFIAPLVPTGLAAGRIGNFINGELWGRPVEAELPW
                     AMVFPWVDAVPRHPSQLYQAAGEGLLLFLVLWLYSASPRPLRAVSAMFLVGYGTLRFM
                     AEFFRTPDPGIFGTLSLGLSTAQWLCVPMVLAGLLLLAAAKRHEHGPQAGGKAGS"
     gene            complement(4850..5527)
                     /locus_tag="P5537_10350"
     CDS             complement(4850..5527)
                     /locus_tag="P5537_10350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceH family protein"
                     /protein_id="HRV78483.1"
                     /translation="MQDTTPTTEAGFDLDPAEIRVLGVLIEKSFITPDAYPLSVNAIT
                     TGCNQLTAREPVMSLSETEVQDAVDRLIARRLVSKRDQQSARVAKYEHLVRLRHSLPP
                     AEQAVLAILLLRGAQTAGELRQRCERLHRFDDVAAVDAVLEHLAEKYPPLVAALPRAP
                     GTKETRHVHLLGGDAAVQEMAEAQSAGAGSGGRGRIGELEDEVRRLREELDALRGEFA
                     AFRKQFD"
     gene            5677..7527
                     /gene="ilvD"
                     /locus_tag="P5537_10355"
     CDS             5677..7527
                     /gene="ilvD"
                     /locus_tag="P5537_10355"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002944474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HRV78484.1"
                     /translation="MPQYRSRTSTAGRNMAGARALWRATGMKDGDFEKPIIAIANSFT
                     QFVPGHVHLKDLGQLVAREIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIAD
                     SVEYMCNAHTADALVCISNCDKITPGMLMAALRLNIPAIFVSGGPMEAGKVKWEAKVI
                     SLDLVDAMVKAADKSCSDEEVDAIERSACPTCGSCSGMFTANSMNCLTEALGLSLPGN
                     GTTLATHADRERLFKEAGRRIVDLARRYYEKDDASVLPRSIASFQAFENAISLDVAMG
                     GSTNTVLHLLAAAREAGVDFTMKDIDRISRHVPCLCKVAPAIADVHIEDVHRAGGIMS
                     ILGELDRAGLLHTGVPTVHSASMAEALDKWDIKRTSDEAVHAFYRAAPGGVPTQVAFS
                     QDRRWKQLDADREHGIIRDKAHAFTADGGLAVLYGNIAEKGCIVKTAGVDESIWKFTG
                     KARVYESQEDAVEGILGEQVQAGDVVVIRYEGPKGGPGMQEMLYPTSYLKSRGLGAQC
                     ALLTDGRFSGGTSGLSIGHASPEAACGGAIALVEDGDTIEIDIPNRSINLAIPAEELA
                     RRRAAMEAKGNAAWKPVKRERVVSAALQAYAALTTSADTGAVRDVTQVQR"
     gene            7578..7772
                     /locus_tag="P5537_10360"
     CDS             7578..7772
                     /locus_tag="P5537_10360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78485.1"
                     /translation="MDTELAQLEAQLEHLISHYERLKADNAALRGRVVQLEGENRRLS
                     DKVRVAADRLEGLLDKLPEA"
     gene            7777..8079
                     /locus_tag="P5537_10365"
     CDS             7777..8079
                     /locus_tag="P5537_10365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000917 - division septum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HRV78486.1"
                     /translation="MSAEHLDMTLLGKEYRISCTAETRDELLATVAFLDDKLREIGAR
                     TGSSGEKLAVMTALNIAHEFLQHQRGNGFDMPGMKRRIGLMKARLDGVLGQQEKLF"
     gene            8103..8286
                     /gene="ssrS"
                     /locus_tag="P5537_10370"
     ncRNA           8103..8286
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="P5537_10370"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            8451..9908
                     /locus_tag="P5537_10375"
     CDS             8451..9908
                     /locus_tag="P5537_10375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter TrkG"
                     /protein_id="HRV78487.1"
                     /translation="MQAYFPVLGVLGMMLMLFGLVMGFPLAVSFALDDGATQAYDLAI
                     LATFATGLAMWLGGRRTRRDLHVSDGFLLVAATWLITPVFGALPLMFYLPELSFTDAY
                     FEAASGLTTTGATVLTGLDTMPVSINLWRCFMHWVGGMGVIVLMVAVLPLLGIGGRQI
                     FRAETPGPMKESSLTPRIAETAKGLWGVYVVLTVACGIALWQAGMLPWDAVIHAFSIM
                     GLGGFSTRDASLGAFDSVPIETVTIVFALLSGINYATHYLALVHRTPRPYGQDPELRW
                     FFGVLAVTVVFLTVYLLEGGAYRDGALAFRHVSFHAVSLATSLGLATYDYTLWPMFAQ
                     VWILFLSSFAACSGSTGGGIKMMRAIILYKQVHREIVRSLHPSAVVPLRLGSQRVSDN
                     VLHAVLAFSFMYMVSIVSLTLVLAASGMDLITAFSGVVACLNNAGPGLASVGPAGNYQ
                     GLGDFQTWVLSFAMILGRLEIFTLLVVLTPAFWRR"
     gene            complement(9865..10611)
                     /locus_tag="P5537_10380"
     CDS             complement(9865..10611)
                     /locus_tag="P5537_10380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV78488.1"
                     /translation="MKSPHARSPVVLLVEDDAGIRRFVRTALESEGCTAHEATALERG
                     RIELASRRPDLLVLDLGLPDGDGMTLLAELRGWSGMPVLVLSARSDEADKVAALDAGA
                     DDYLAKPFGVGEFLARVRALLRRALRPAQAAARIAFGDVELDLEQRRVTRAGVPVHLT
                     PIEFRLLSLLAAAAGRVVTQRQLLAGAWGPNHVEHAHYLRVYMAGLRRKLEADPRLPK
                     RILTEPGVGYRLVPEPLSAARTPASAPPAG"
     gene            complement(10608..11885)
                     /locus_tag="P5537_10385"
     CDS             complement(10608..11885)
                     /locus_tag="P5537_10385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004373622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4118 domain-containing protein"
                     /protein_id="HRV78489.1"
                     /translation="MKRASSSAPRLAPSRNYLLAALVVAAVALLGAPLLGQFDLANIA
                     MLFPLAVLFAAIRLGRGPAVFAAFLAVALFDFFFVHPHFTLAVSDLQYLLTFAVLLAV
                     ALTTAELAARLRRERDSAEARAQEVAQARLAADSERLRNTLLASLSHDLRTPLTALAG
                     LAESLPLAGPPLPPAQAELAEAIRAEAVRTHALARDLLDLARLQSDTPRLALDWLAVD
                     ELVGSALQARGHALREHMLTLDLPEELPLLHADAVLMERVVCNLIDNAIAHTPAGGHI
                     TLSAQVGAPPADAPSCTMNPASAPSHAASAGRGSPSDRAADPGPRSGASWLRIRVCDD
                     GCGLPPGREQAIFERFVRAPHPRGPSDAATATGDSGTGLGLAIVHAIMAAHGGSVSAH
                     NRAGGGACFELQLPLPAQPERPPPEDEAGEPTR"
     gene            12052..12435
                     /gene="crcB"
                     /locus_tag="P5537_10390"
     CDS             12052..12435
                     /gene="crcB"
                     /locus_tag="P5537_10390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004373620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HRV78490.1"
                     /translation="MNLAAFAAVGVGAACGAWLRWGLGLWLNPLFVLLPLGTLVANLL
                     GGFLMGVALAAVQAWPTMSPALKLLLTTGLLGGLTTFSTFSAEAFHLLQRGALGWLGA
                     HLVVHVAGSVLMTWAGYALFNALRA"
     gene            12570..13241
                     /locus_tag="P5537_10395"
     CDS             12570..13241
                     /locus_tag="P5537_10395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004373615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HRV78491.1"
                     /translation="MKKIIVTLSAISLSMAGLSGCANMNETQRDTGMGAAIGAVAGGL
                     IGAATAGGNKGKSAATGAAIGAALGAGGGYLWSQNMQKQRAEMEQATAGTGIGISQTT
                     DNQLKVDIPADVSFDVGRYAIKSNMRPVLDRLASTLNQHPVTTVTIIGHTDSTGSDAV
                     NDPLSINRAAATRDYLVQRGVSAQRIAVDGRGSRQPVADNSTASGRAMNRRVEIFIAE
                     PAQQR"
     gene            complement(13383..>15875)
                     /locus_tag="P5537_10400"
     CDS             complement(13383..>15875)
                     /locus_tag="P5537_10400"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HRV78492.1"
                     /translation="AADRVLPLLPPWYIDTARAEAGPIALQVPAELVQRLLWLPPLSQ
                     AESELVADTLAEVAPALPAPTQRGEPPVELGGVPVPVLRLETRPAYHARFRQYAPHGT
                     YQFDFALLAFRYGTVSVEAGDARLFHPLPDGRSARLTRDEEAERTAAQRLAAAGFTRI
                     PPGAVQTSFGSLPTDALGLASEAAWPDFMAETVPALRTEGWEVAFPSDFRHHAIDIDH
                     LMLDIDEHEDGWLGLSPGIEIDGRALPLAPLLAGLFAHDPRWLSGRLDDIDDREAVIL
                     EDETLGRLRIGAARIKPLVRALVDLFDRPDHDWRLSRLDAARLADLDLPGRGREQVAA
                     IAARLRDAERIRAVAAPAGFRAELRPYQLEGLAWLQHLVRHDLAGILADDMGLGKTAQ
                     TLAHLLTEKQAGRLDVPALVVLPTSLVFNWQAEAERFAPDLKVLNLHGADRHARFEEL
                     DAGDGNVDIALTTYPLLWRDAELLQAREWSLLILDEAQTVKNAASKGAQVIRQLKARH
                     RLGLTGTPLENHLGELWAQFDFLLPGFLGSHKDFTATWRTPIEKHGDTVRRDLLAARL
                     RPFILRRRKEDVATELPPKTIIVRSVGLEGGQRDLYETVRAAMDEKVRAEIAGKGFAR
                     SQIVILDALLKLRQVCCDPRLLKSPAALRVKERAKLDLLMDMLPELIDEGRRILVFSQ
                     FTTMLGLIAAELDKAKIGWVALTGDTRDRRIPVEDFQKGRVPVFLISLKAGGVGLNLT
                     AADTVIHYDPWWNPAAENQATDRAHRIGQDKPVFVFKLVCAGSIEEKILALQERKAAL
                     AESVLSEDADALAKFGEADIAALLAPLPTSGR"
     assembly_gap    15876..15975
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<15976..16489)
                     /locus_tag="P5537_10405"
     CDS             complement(<15976..16489)
                     /locus_tag="P5537_10405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HRV78493.1"
                     /translation="MNLLEAFTQDDLIAALGVETVAKGLGYVSRVSALSAEGNTVSAL
                     VKGRQRTPYTVEAEVEEESGLADGASILTSSCTCPMGFGCKHVAAMMLVWLHQRRRPD
                     RPREQVLAWVKGFREAAGSLAMDGSRKRKPASATYALRYVVEPSLYGGDFSVKCHKVR
                     LDQHGEIRQHE"
     gene            complement(16648..>17505)
                     /locus_tag="P5537_10410"
     CDS             complement(16648..>17505)
                     /locus_tag="P5537_10410"
                     /EC_number="4.1.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004293502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HRV78494.1"
                     /translation="GIVSRGGSIMAKWCLAHHKESFLYTHFEDICEIMKAYDVAFSLG
                     DGLRPGSIYDANDEAQLGELKTLGELTEIAWRHDVQVMIEGPGHVPLQLIKENMDLQL
                     EWCKEAPFYTLGPLTTDIAPGYDHITSGIGAATIGWYGTAMLCYVTPKEHLGLPNKQD
                     VKEGIITYKLAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDKAKEFHD
                     ETLPKDSAKVAHFCSMCGPHFCSMKITQDVRDFAAQQGIDEAEALKKGMEVKSVEFVK
                     GGAEVYRNV"
BASE COUNT         2604 a         5885 c         6213 g         2703 t
ORIGIN      
        1 gaagggggtg gcgagtactc atcggcccgg ctccggatgg aggctttgca agtgtcttag
       61 ggtggcgtcg ccgtcgagcg gccgcgagaa caggtagccc tggccgaagt cgcagcccat
      121 cgcccgcagg atctcgagct gcgcctcgtc ctcgatgcat tcggcgacga cggtcatgcc
      181 gaggtcgtgg gcgagctcga tgctgtggcg cacgatcgcg cgcaggcgct ggtcgtgggg
      241 gagcgagcgt acgaaggagc cgtcgagctt gacctggttg cagggcatgg tgtgcaggta
      301 gctcagcgtc gagtagccgg tgccgaaatc gtcgatcagg atgtcgatcc cggcggcgcg
      361 cagggcgtgg aggtggtcga tcgccgggcc gtcggggtgc gccagtacgc tctcggtgac
      421 ctcgaaacgg atgcggtcgt gcgccacgcc gctgcgatcg atgacgtcga gcagttcggc
      481 cgcgagatcg ggacgcgcga gctggcgcgc ggagagattc acgctgacgc gcagcggggc
      541 atcgaaaggc agctggctcg accatgcctg cagatccgtg caggttcgct cgagtacgat
      601 catcccgatg tcgtggatga ggtcgagcgc ctcggcgagc ggaatgaatt cggcagggga
      661 gagcaggccg agcgtcgggt gcggccagcg caccagggcc tcgaagccgg tcgggcgccg
      721 gttcgccagt tccacgatcg gctggtacca ggtctgcagc ccgccctggg tgagcgcctt
      781 gcgcaattcg gcttccacct gcagcgcgcg caccgcggcc gcatgcatct cggtctggaa
      841 gaactcgatc gggccggtgt cgctgcggcg ggccttgtgc agcgcgttgt cggcgtcgcg
      901 cagcaaggat tcggcgtcct cgcgctcgtt gtcgctgatc gcaacgccca ccctgcagcg
      961 tggatgcaac tgctggccgt tgccgttggg tgagaaggcc gggagcgcga cgagttgttc
     1021 gcagatgcgc agcgcgtcga tcgagttctc cacgccgttg agcagcacgg cgaactggtc
     1081 gccgccgacg cgcgcgcata cgtccccgtc gcgcatcagc gcggcgatgt gggcgccgat
     1141 tcggcgcagc agctcgtcgc cgacgagatg gccgtagctg tcgttgacca ggctgaagcg
     1201 ctcgaggttg atcgccagca ccgcaatctg tgcgaggtcg ccgcgcctgc gctgggcgag
     1261 tgcacggttg gcgtgctcga tgaacatcgc ccggttgggc aggccggtga ggccgtcgtg
     1321 cagggcatcg tgcaccagtt gctgctcggc gcgcttgcgc aggtcgatgt cgccgagcga
     1381 tcccgccatc cggtaggcgc gcagatcctc gtcccgatcg gcgaccccgc gcatcaggac
     1441 ccagcggtag gcgccgtcgg gcaggcgggc gcgcaactcc atgatgaagt ggttgctgtt
     1501 gcccttgagg tggtcgatga ggcgctggcg gtaggcctcg acctcgtgcg ggtgcaggta
     1561 ggcgaggatg tcctcgggct tgctggagag gctgccaggc tccacgccaa gaatctggca
     1621 gaagcgttcg gagtagtaga cgtcgtcggc gtcgatgtcc cagtcccaca ggccgtcgtt
     1681 cgagccgcgc agcgcgaggg cgtagcgttc ctcgctcgcc tgcaggcgct cggccgtgtc
     1741 ctgcaactcg gcaatgcggt tctgaagtgt cgccgccatc acgttgaagt ggtcggcgat
     1801 cacggcgagc tcgtccttgc cgcgcgactc cacccggtgg tcgaggaagc cgctggcgat
     1861 cgcacggctg ccttccagga gcaggcgaag gttgcgggtc aggagatatc cgagcgagga
     1921 gagcaggacg aaggtcagca ggatctccgc gatcgcgatc gcgaggccct gctgcatgat
     1981 cgcctcgcgc gccgctgcga gcaccgacac cgagacgccg aactggagcg tgccgacctc
     2041 attgcgcgcc agcagcagtt gtcggcgcac gtgtacgagg tcgtcggcca gcaaggtctc
     2101 gaagaagcgg cggcggtgct cgttgggttc ggggacgtgc gtcagatcgg gcatgccggc
     2161 gctcaccagc agatcgtcgc gggcgtcccg gatgcgcacg tagagcagcc cttcgtcggc
     2221 atcggccagc aactcgccga ggacgtcctc gagtgcgtcg agccgccgct gttcgccata
     2281 cgcggtggcc atcgcgtgca gcatgctcgc ggtctggccg atggtcgtct ccaggctcgc
     2341 cgacatcgcg ttgttcatca gccgtacgct gttggcgagc agcaggctga gcaggacgac
     2401 ctgcaccacc gtgctggcga gcagcaggcg gatccggatc gaggaggggc gcagatcgaa
     2461 cgagatgggc ggcacgcgca cctcagcgcc gggcgagcct gcgcaccgcg gacgaggccg
     2521 cgatgctgcc gttggctgcg aagttctcga ggttggcttc caggctgtcc gggtcgtaga
     2581 ggtaattgac catcatcccc caggactggc ggagcccctt gtcggagcgg tcggcaagcc
     2641 agttcaggcg ctcgatgcgg gcgccgttgc cgaggtggaa gcgcgccacc gaatcgaccg
     2701 ggcggtcgcc gcggcgcgcc tcgctcagat agcgcgcgcc cagacgcagc agcggctcgc
     2761 gcaaggccag ggcgagcgcc tcgtccgcga cccacgccgg atcgccggcg agcagcgcgg
     2821 cgaggcgggg tgagtcgccg ccttcgacac ccagcgcggc aaggcgcttc cagtcggttg
     2881 cattgaacgc ctcggcgaag gcttccgggt cgcgctgcgc ccagcgcacc aggccgggga
     2941 tgggcgagag cgtggcgaag gtcttcaggc gcgggaagtc gcgcttgagg tcgtcgatca
     3001 cccgcttgag gaggaagttg ccgaagctca cgccacgcag gcccttctgc gtggcgctga
     3061 tcgaatagaa gatcgccgtg gtcgcccggc ccgcgtcggc gagcggcgcc tcgatgtcga
     3121 gcaggcgctg cacatcgtcg gcgatctcct cgagcagcgc gacctgcacg aagatcagcg
     3181 gctcgagggg catgcgcgga tggaagaagg catagcagcg ccggtcggag tccagccggt
     3241 tcttgagatc cttccacgag cggatctcgt gcaccgcctc gtactcgacg agcttctcga
     3301 gcagggcggc cggcgaactc caggtgatgc gctgcagttc gaggaagccg acgtcgaacc
     3361 atgccgacag ccgggtctcg agctcgcggt ctagcggctt gagcagcgga tcgtcggcga
     3421 tgaagcgcag caggtcggcg cgcaggtcga cgaggaactt gacgccctgc gggatggcgt
     3481 tgaactgggt gaggatgcgc agccggcgcg agcgcagcgc ggtgcgcagc tcggcctccg
     3541 catcccactg tcctgcggtg ccgatcgccg cctggtaggc ggcatgggcc gcggccacgc
     3601 gcgaggggtc cgggccgaac tcatgggcga tcaggcgcag gaaggcatgg cggccggcgt
     3661 cgtccaggcg caggtaggtc tccgccaggc gggcggcgcg ctgccgggtc gacacctcgc
     3721 caccgcgacc ttcggcgcac tcctggagct gggtgcgcag gcgttcgagg tcgctctcgt
     3781 ccggcgcctt gccgagatgc gcggcgctcg cgacgagttc gcgcacgcgg ctcagtccgc
     3841 gggagaccag tcctgctccg ctcatgtcgt cctcctgccg attcgattcg gatatcgctc
     3901 ttacatgata gcccgctttg gggagtggct tgtcggcgcc ccggagcgct cgtgtgcgat
     3961 attcacgatc ccgccttgcc cccggcctgc gggccgtgct catgccgctt tgcggcggcg
     4021 agcagcagca ggccggcgag caccatcggc acgcacagcc attgcgcggt ggacaggccg
     4081 agcgagaggg tgccgaaaat gcccgggtcg ggcgtgcgga agaactccgc catgaagcgg
     4141 agcgtgccgt agccgaccag gaacatggcc gacaccgcgc gcagtggccg cgggcttgcg
     4201 gagtagagcc aaagcaccag gaacagcagc aggccctcgc ccgcggcctg gtaaagctgc
     4261 gaggggtggc gcggcaccgc gtccacccag gggaagacca tcgcccacgg caactccgcc
     4321 tccaccgggc ggccccacag ttcgccgttg atgaagttgc cgatccgtcc ggccgccagc
     4381 ccggtcggca ccagcggcgc gatgaagtcg gtgacctgcc agaagtcctt gccgtggcgg
     4441 cgaccgtaca gccacatcgc cgccagcacg ccgagaaaac cgccgtggaa gctcatcccg
     4501 cccttccaca cggccaggat ctcaccgggg tgttgcaggt aatagccggg ctggaagaac
     4561 agcacttcgc cgaggcgccc ccccaggatc accccgatca ccccgtacat gagcaggtcg
     4621 tcgataccct gcgcatccca gcccagttcg ggacgccgcc gcgcgtgacg acggccgagc
     4681 acgacgaaga gcacgaaggc gaccaggtac atgagcccgt accagcgcac cgagagcggg
     4741 ccgagggaga gtgcgatcgg atcgaattgc ggatgaacga gcatgggggg cgtgaggcgt
     4801 gaggcgtgag gcgtgaggcg tgaggcaccg cgtgcgcggc gggcggcggt cagtcgaact
     4861 gcttgcggaa cgcagcgaac tcgccgcgca gcgcgtcgag ctcctcgcgc agacggcgga
     4921 cctcgtcctc gagttccccg atgcgcccgc gcccgccgct gcccgcgccg gcggactgcg
     4981 cctcggccat ctcctgcacc gcggcgtcgc cgccgagcag atgaacgtgg cgggtctcct
     5041 tggtgccggg cgcgcgcggc agcgcggcga ccaggggtgg gtacttctcg gccaggtgct
     5101 cgagcacggc atccaccgcg gcgacgtcgt cgaagcggtg caggcgctcg cagcgctggc
     5161 gcagctcgcc cgcggtctgt gcgccgcgca gcagcaggat cgccagcacc gcctgctcgg
     5221 cgggcggcag cgagtgacgc aggcggacca ggtgctcgta cttggccacg cgtgcgctct
     5281 gctggtcgcg cttggacacc aggcggcggg cgatgaggcg gtcgaccgcg tcctgcacct
     5341 cggtctcgga aaggctcatc accggctcgc gcgcggtgag ctggttgcag ccggtggtga
     5401 tggcgttgac cgacagcgga taggcgtcgg gggtgatgaa ggatttctcg atcagcacgc
     5461 cgagcacgcg gatctcggcg gggtcgaggt cgaagccggc ctcggtcgtg ggggtcgtgt
     5521 cctgcatgga acctcctgcg gtgtcgggcc ccggatgata cgccagccgg atcgtccgcc
     5581 ccaccgcggc gtccccgcat gcgccggcgc ttgtcgcaag cctgcgcacc gcgcgttaga
     5641 atcgagccct ttaccgctga tttcccggag cgcgccatgc cccagtaccg ttcccgcacc
     5701 tccaccgccg gccgcaacat ggcgggcgcc cgcgcgctgt ggcgcgccac cggcatgaag
     5761 gacggagact tcgagaagcc gatcatcgcc atcgccaaca gcttcaccca gttcgtgccc
     5821 ggccacgtgc acctgaagga cctcggccag ctcgtcgcgc gcgagatcga ggccgcgggc
     5881 ggcgtcgcca aggagttcaa caccatcgcg gtcgatgacg gcatcgccat gggccacggc
     5941 ggcatgctgt actcgctgcc ctcgcgcgag ctcatcgccg acagcgtcga gtacatgtgc
     6001 aacgcccaca ccgccgacgc gctggtgtgc atctcgaact gcgacaagat caccccgggc
     6061 atgctgatgg ccgcgctgcg cctcaacatc ccggcgatct tcgtctccgg cgggccgatg
     6121 gaggccggca aggtcaagtg ggaggccaag gtcatctcgc tcgacctcgt cgacgcgatg
     6181 gtcaaggccg ccgacaagtc gtgttcggac gaggaggtcg acgccatcga gcgctcggcc
     6241 tgtccgacct gcggctcgtg ctcgggcatg ttcaccgcca actcgatgaa ctgcctcacc
     6301 gaggcgctcg gcctgtcgct gcccggcaac ggcaccacgc tcgccaccca cgccgaccgc
     6361 gagcgcctgt tcaaggaagc cggccgccgc atcgtcgacc tcgcccgccg ctattacgaa
     6421 aaggacgacg cctcggtgct gccgcgctcg atcgccagct tccaggcctt cgagaacgcc
     6481 atcagcctgg atgtggccat gggaggttcg accaacaccg tgctgcacct gctcgccgcc
     6541 gcgcgcgagg ccggcgtcga cttcaccatg aaggacatcg accgcatcag ccgccacgtg
     6601 ccctgcctgt gcaaggtcgc gccggcgatc gccgacgtgc atatcgagga cgtgcatcgc
     6661 gccggcggca tcatgagcat cctcggcgag ctcgaccgtg ccggcctgct gcacaccggc
     6721 gtgcccaccg tgcacagcgc ctcgatggcc gaggcgctcg acaagtggga catcaagcgc
     6781 acttccgacg aggcggtgca tgccttctac cgcgccgcgc ccggcggcgt gcccacccag
     6841 gtcgccttca gccaggaccg gcgctggaag caactcgacg ccgaccgcga gcacggcatc
     6901 atccgcgaca aggcccacgc cttcaccgcc gacggcggcc tcgccgtgct ctacggcaac
     6961 atcgccgaga agggctgcat cgtgaagacc gccggcgtgg acgagtccat ctggaagttc
     7021 accggcaagg cgcgcgtcta cgagagccag gaagatgcgg tcgagggcat cctcggcgag
     7081 caggtgcagg ccggcgacgt cgtcgtcatc cgctacgaag ggcccaaggg tggccccggc
     7141 atgcaggaga tgctgtatcc gacctcctac ctgaagagcc gcggcctcgg tgcgcagtgc
     7201 gcgctgctga ccgacgggcg cttctcgggc ggcacctcgg gcctgtcgat cggccatgct
     7261 tcgcccgagg cggcctgcgg tggcgcgatc gcgctggtcg aggacggcga caccatcgag
     7321 atcgacatcc cgaaccgcag catcaacctg gcgatcccgg ccgaagagct cgcccgccgg
     7381 cgcgcagcga tggaggcgaa gggcaatgcc gcgtggaagc cggtgaaacg cgagcgcgtc
     7441 gtctccgccg cgctgcaggc ctatgccgcg ctcaccacct cggccgacac cggcgcggtg
     7501 cgggacgtca cccaggttca gcgctgaccg tccccggccg attgacccgt catcggccgc
     7561 tcactaccat cgacgccatg gataccgaac tcgcacagct cgaagcccag ctcgagcacc
     7621 tgatcagcca ctacgagcgc ctgaaggccg acaacgccgc cctgcgcggt cgcgtcgtgc
     7681 agctcgaggg cgagaatcgc cggctctccg acaaggtccg tgtcgccgcg gaccgcctcg
     7741 agggcctgct cgacaaactg ccggaggcct gaagcgatgt ccgccgaaca cctcgacatg
     7801 acgctgctgg gcaaggagta ccgcatctcc tgcacggccg aaacgcgcga cgaactgctc
     7861 gccaccgtag cctttctcga cgacaagctg cgtgaaatcg gtgcccgcac cggctcgtcg
     7921 ggcgagaagc tggcggtcat gaccgccctc aatatcgccc acgagttcct ccagcaccag
     7981 cgcggcaacg ggtttgacat gccgggcatg aagcgtagaa tcggactcat gaaagcgcgc
     8041 ctggacggtg tcctggggca gcaggaaaag cttttctgaa ggcagttcga gcaataccgg
     8101 tcaatcccct gcagtgttcg tcgaagtcgt agactccttg aaccaatagt cgagagactc
     8161 ggtcgccgac catcgatgcc gctggtgtga acgccccttg ccgggtgatc ctgaagcgga
     8221 aggaacgcga cctccctgaa cccaaggttc aggatgcccg gcggagacgg cacaggcggg
     8281 ggacctacaa agagagggcg cggtgagcga tcaccgcgcc ctctgcgctt gtacgcacct
     8341 cacgcctcac gctcgtgctg cactgcaaac tcttaacgcc atctttacgc ccgccggcct
     8401 agcatccgct gcatccataa cgctttgcgg cccttgccgc tcatgttgcg atgcaagcct
     8461 actttcccgt cctcggtgtg ctcggcatga tgctgatgct gttcgggctg gtgatgggct
     8521 ttcccctcgc ggtctcgttc gcgctcgacg acggcgccac ccaggcctac gacctcgcca
     8581 tcctcgccac cttcgccacc gggctggcga tgtggctggg cgggcggcgg acgcggcgcg
     8641 acctgcacgt ctcggacggc ttcctgctcg tggctgcgac ctggctgatc accccggtgt
     8701 tcggtgcgct gccgctgatg ttctaccttc cggagctgtc cttcaccgac gcctacttcg
     8761 aggccgcctc cgggctcacc accaccggcg ccacggtgct caccgggctc gacacgatgc
     8821 cggtgtcgat caacctgtgg cgctgcttca tgcactgggt gggcggcatg ggcgtcatcg
     8881 tgctgatggt ggcggtgctg ccgctgctgg gcatcggtgg gcggcagatc ttccgcgccg
     8941 agacgccggg gccgatgaag gagtccagcc tcaccccgcg catcgccgag accgcgaagg
     9001 gcctgtgggg tgtctacgta gtgctcaccg tggcctgcgg aatcgcgctc tggcaggccg
     9061 ggatgctgcc ctgggacgcg gtgatccacg ccttctcgat catggggctg ggcggcttct
     9121 ccacccgcga cgccagcctc ggcgccttcg acagcgtacc gatcgagacg gtcaccatcg
     9181 tgttcgcgct gctctcgggg atcaactacg ccacccacta cctcgccctg gtgcaccgaa
     9241 cgccgcgccc ctacggccag gaccccgaac tgcgctggtt cttcggcgtg ctcgcggtca
     9301 ccgtggtgtt cctgaccgtc tatctgctcg agggcggcgc ctaccgggat ggcgcgctcg
     9361 ccttccgcca cgtctccttc cacgccgtct cgctggcgac ctcgctcggc ctggcgacct
     9421 acgactacac gctgtggccg atgttcgccc aggtgtggat cctgttcctg agcagcttcg
     9481 ccgcctgctc gggctcgacc ggcggcggca tcaagatgat gcgtgcgatc atcctttaca
     9541 agcaggtgca tcgcgagatc gtgcgctcgc tgcatccgag cgcggtggtg ccactgcgcc
     9601 tgggcagcca gcgcgtctcc gacaacgtgc tgcacgccgt actggcgttc agcttcatgt
     9661 acatggtcag catcgtcagc ctgaccctcg ttctcgccgc ctccgggatg gacctgatca
     9721 ccgcgttctc gggtgtggtc gcctgcctca acaacgccgg ccccggcctg gcttcggtag
     9781 gccccgcggg caactatcag ggcctgggcg atttccagac ctgggtactg agcttcgcga
     9841 tgatcctcgg ccggttggag atctttaccc tgctggtggt gctgacgccg gcgttctggc
     9901 ggcgctgagc ggttcgggca cgagccggta gcccacaccg ggctcggtga ggatgcgctt
     9961 cggcaggcga gggtcggcct cgagcttgcg gcgcaatccg gccatataga cgcgcaggta
    10021 gtgggcatgc tcgacgtggt tcggccccca ggctccggcg aggagctgac gctgcgtcac
    10081 cactcgcccg gcggccgcgg cgagcaggct gagcaggcgg aactcgatcg gggtgaggtg
    10141 caccggcacg cctgcacgcg tcacgcggcg ctgctcgaga tcgagctcga cgtcgccgaa
    10201 ggcgatgcgc gcggcggctt gcgccggacg caaggcgcgg cgcagcaggg cgcgcacgcg
    10261 ggcgaggaac tcgccgacgc cgaagggctt ggcgaggtag tcgtcggcac cggcgtcgag
    10321 cgcggcgacc ttgtcggcct cgtcgctgcg cgccgacagc accagcaccg gcatgccgct
    10381 ccagccgcgc agttcggcca gcagggtcat gccgtcgccg tcgggcaggc cgaggtcgag
    10441 caccagcagg tcggggcgac ggctggcgag ctcgatgcga ccgcgctcga gcgcggtggc
    10501 ctcgtgcgcc gtgcaaccct cggattccag cgctgtgcgc acgaagcggc ggatgccggc
    10561 gtcgtcctcg accagcagca cgaccgggga acgggcgtgg gggctcttca tcgagtgggc
    10621 tctccggcct cgtcctcggg cggcggtcgt tcgggctgcg ctggcagcgg cagttgcagc
    10681 tcgaagcagg cgccgccgcc ggcgcggttg tgcgcgctca cgctgccgcc gtgcgccgcc
    10741 atgatcgcgt gcacgatcgc caggccgagg cccgtgccgc tgtccccggt cgcggtcgct
    10801 gcatcgcttg ggcctcgcgg atgtggcgca cgcacgaagc gttcgaagat cgcctgttcg
    10861 cggccgggcg gcagaccgca gccgtcgtcg cacacgcgga tgcggagcca gctggcgccg
    10921 gaccgcggtc ctgggtccgc agcccgatcc gacggactgc cgcgcccggc gctggccgcg
    10981 tgcgatggcg cagacgccgg gttcattgtg cagctcggcg catccgcagg cggggcgcca
    11041 acctgtgccg acagtgtgat gtgcccgccc gcgggagtgt gcgcgatcgc gttgtcgatc
    11101 aggttgcaga ccacccgctc catcagcacc gcgtccgcgt gcagcagcgg cagctcctcg
    11161 ggcaggtcga gcgtgagcat gtgttcgcgc agggcgtggc cgcgcgcctg cagggcgctg
    11221 ccgaccagtt cgtccaccgc cagccagtcg agcgcgaggc gcggcgtgtc cgactgcagg
    11281 cgggcgagat cgagcaggtc acgcgcgagc gcatgggtgc gcacggcctc ggcacgaatc
    11341 gcctcagcga gctcggcctg cgccggcggc agcggcggac cggccagcgg cagcgattcg
    11401 gccagcccgg cgagtgcggt gagcggcgtg cgcaggtcgt gcgacaggga ggcgagcaag
    11461 gtgttgcgca ggcgctcgct gtccgcggcc aggcgcgcct gtgccacctc ttgcgcgcgc
    11521 gcctcggcgg agtcgcgctc gcggcgcagg cgcgcggcca gctcggcggt ggtcagcgcc
    11581 acggcgagca gcacggcgaa ggtcagcagg tactgcaggt ccgacaccgc cagggtgaag
    11641 tgcggatgca cgaagaagaa gtcgaacagc gccaccgcca ggaaggcggc gaataccgcc
    11701 gggccgcgcc cgagccggat cgcggcgaac aggaccgcga gcgggaacag catcgcgatg
    11761 ttggcgaggt cgaactgccc gagcagcggc gcgccgagca aggccaccgc agcgaccacg
    11821 agcgcggcga gcaggtagtt gcgcgacggc gcgagacgcg gggcggatga ggaggcgcgc
    11881 ttcatgcgga gatggtagca gcgcggccgc ccccgatctc gtgtcggcgc tgccgacgct
    11941 cgcgattccg cttccatcct gccggtcgtc ctggcgcgag gggtgggtag aatgccggat
    12001 ggggccggat gtggggccga gtgaggatgg aggcgggatg ggggacctac gatgaatctt
    12061 gcggcattcg cggcggtggg cgtcggcgcg gcgtgcggcg cctggctgcg ctggggcttg
    12121 ggtctgtggc tgaatccgct gttcgtgctg ctcccgctcg gcaccttggt ggcgaacctg
    12181 ctcggcggct tcctgatggg cgtcgcgctg gcggcggtgc aggcctggcc aacgatgtcg
    12241 ccggcgctca agctcctcct caccaccggc ctgctcggcg ggttgaccac tttttccacc
    12301 ttttccgccg aggccttcca cctgctgcag cgtggtgcgc tcggctggct gggcgcacac
    12361 ctggtcgtcc atgtggccgg atccgtgctg atgacctggg ccggttatgc gcttttcaac
    12421 gccctgcgcg cgtgacctac ggcgcaaggc gggcggcagc ttcattttct gtttcactcc
    12481 gatgggctag agtgaatgca cggcacatcc ataattcacg ccgaaccgca tccccggcag
    12541 taccccctca acgcaacgga ggccattaca tgaagaaaat catcgttacc ctttccgcga
    12601 tctcgctttc gatggcaggt ctctcgggct gcgccaacat gaacgagacc cagcgcgaca
    12661 cgggcatggg cgccgcgatc ggtgccgtgg ccggcggcct gatcggtgcc gccacggcgg
    12721 gcggcaacaa gggcaagagc gccgccaccg gcgcggcgat cggcgccgca ctgggtgcgg
    12781 gcgggggcta cctgtggtcg cagaacatgc agaagcagcg cgccgagatg gagcaggcga
    12841 ccgcgggcac cggcatcggc atcagccaga ccaccgacaa ccagctcaag gtcgatattc
    12901 ccgcggacgt gtccttcgat gtcggccgct acgcgatcaa gtccaacatg cgcccggtgc
    12961 tcgaccgcct cgcgtccacg ctgaaccagc acccggtgac gaccgtgacc atcatcggcc
    13021 acaccgacag caccggctcc gatgcggtca acgacccgct gtcgatcaac cgtgccgccg
    13081 ccacccgcga ttacctggtg cagcgtggcg tgtccgcgca gcgcatcgcg gtcgatggcc
    13141 gcggctcgcg ccagccggtc gccgacaact cgacggcctc cggccgcgcg atgaaccgcc
    13201 gcgtggagat cttcatcgcg gagccggcgc agcagcgctg attccgatgc cggcgggacg
    13261 aggggccgtg gctggaaggc cgcttgcggt ctctcgatcg tcgctgtcgc atccggacac
    13321 atgagggcag gttttgcctc ttccgacgcc cccacacggg ggcgtcgtcg tttcagccct
    13381 gctcagcgcc cgctcgtcgg cagcggcgcg aggagtgcgg cgatatcggc ctcgccgaac
    13441 ttggccagtg catcggcgtc ctccgacagc acgctctcgg cgagcgccgc cttcctctcc
    13501 tgcaaggcga ggatcttctc ctcgatgctg cccgcgcaca ccagcttgaa cacgaacacc
    13561 ggcttgtcct ggccgatgcg gtgggcgcgg tcggtggcct ggttctcggc cgctgggttc
    13621 caccacgggt cgtagtggat cacggtgtcg gccgcggtga ggttgaggcc cacgccgccc
    13681 gccttcaggc tgatcaggaa caccggcacg cgacccttct ggaagtcttc caccgggatg
    13741 cggcggtcgc gggtgtcgcc ggtcagcgcg acccagccga tcttcgcctt gtcgagttcg
    13801 gccgcgatca ggccgagcat ggtggtgaac tgcgagaaca ccaggatgcg ccggccctcg
    13861 tcgatcagct cgggcagcat gtccatcagc aggtcgagct tggcgcgctc cttgacccgc
    13921 agggcggccg gcgacttcag caggcgcggg tcgcagcaca cctggcgcag cttcagcagc
    13981 gcatccagga tcacgatctg gctgcgtgcg aagcccttgc cggcgatctc ggcgcgcacc
    14041 ttctcgtcca tcgccgcgcg caccgtctcg tagaggtcgc gctggccgcc ctcgaggccg
    14101 acgctgcgca cgatgatggt cttgggcggc agctcggtgg cgacgtcttc cttgcgccgg
    14161 cgcaggatga agggtcgcag gcgcgccgcg agcaggtcgc ggcggaccgt gtcgccgtgc
    14221 ttctcgatcg gcgtgcgcca ggtcgcggtg aagtccttgt ggctgccgag gaagcccggc
    14281 agcaggaagt cgaactgcgc ccacagctcg ccgaggtggt tctccagcgg cgtgccggtg
    14341 aggcccaggc ggtggcgggc cttcagctgc cggatcacct gcgcgccctt gctggcggcg
    14401 ttcttcaccg tctgtgcctc gtccaggatc agcaggctcc actcgcgcgc ctgcagcagc
    14461 tcggcgtcgc gccacagcag ggggtaggtg gtgagggcga tgtcgacgtt gccgtcgccc
    14521 gcgtccagct cctcgaagcg cgcgtggcgg tcggcgccgt gcaggttcag caccttcagg
    14581 tcgggggcga agcgctcggc ctcggcctgc cagttgaaca ccagcgaggt cggcagcacg
    14641 accagggcgg ggacgtccag gcggcccgcc tgcttctcgg tgagcaggtg ggcgagcgtc
    14701 tgcgcggtct tgcccaggcc catgtcgtcg gcgaggatgc cggcgaggtc gtggcgcacc
    14761 aggtgctgca gccaggcgag gccctcgagc tggtagggac gcagctcggc gcggaagccc
    14821 gccggggcgg cgacggcgcg gatgcgctcg gcgtcgcgca ggcgggcggc gatcgcggcg
    14881 acctgctcgc gtccgcggcc gggcaggtcg aggtcggcga ggcgggcggc gtcgagcctc
    14941 gacagccgcc agtcgtggtc aggacggtcg aagaggtcga ccagcgcgcg caccagcggc
    15001 ttgatgcgcg cggcaccgat gcgcaggcgg ccgagggtct cgtcctccag gatcaccgcc
    15061 tcgcggtcgt cgatgtcgtc caggcggccg gacagccagc gtggatcgtg cgcgaacagg
    15121 ccggcgagga gcggtgccag cggcagcgcc ctgccgtcga tctcgatgcc gggcgacagg
    15181 cccagccagc cgtcctcgtg ctcgtcgatg tcgagcatca ggtgatcgat gtcgatcgcg
    15241 tggtggcgga agtcgctcgg gaaggccacc tcccagcctt ccgtgcgcag cgccggcacg
    15301 gtctccgcca tgaagtcggg ccaggcggcc tcgctcgcca gcccgagcgc gtcggtcggc
    15361 aggctgccga agctggtctg cacggcgccc ggcgggatgc gcgtgaagcc ggcggcggcg
    15421 agacgctgcg cggcggtgcg ctcggcctcc tcgtcgcggg tcaggcgcgc gctgcggccg
    15481 tcgggcaggg gatggaagag gcgggcgtcg ccggcctcga cgctgaccgt gccatagcgg
    15541 aaggcgagca gggcgaagtc gaactggtag gtgccgtggg gcgcgtactg gcgaaagcgc
    15601 gcgtggtagg cggggcgggt ctccagccgc agcacaggca ccgggacgcc gccgagctcg
    15661 accggcggtt ccccacgctg cgtgggcgcg ggcagggcgg gggcgacctc ggccagggtg
    15721 tcggcgacca gctcggattc ggcctggctg agcggcggca gccaaagcag gcgctgcacc
    15781 agctcggcgg gcacctgcag ggcgatgggg ccggcctcgg ccctggcggt gtcgatgtac
    15841 cagggtggca gcagaggcag cacgcggtcg gcggcnnnnn nnnnnnnnnn nnnnnnnnnn
    15901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15961 nnnnnnnnnn nnnnngctcg tgctggcgga tctcgccgtg ctggtcgagg cggaccttgt
    16021 ggcatttgac gctgaagtcg ccgccgtaca ggctgggctc gacgacatag cgcagcgcgt
    16081 aggtggccga ggccggcttg cgctttcggc tgccgtccat cgcgaggctg cccgcggcct
    16141 cgcgaaagcc cttaacccag gccagcacct gctcgcgcgg gcggtcgggg cgccggcgct
    16201 ggtgcagcca caccagcatc atcgccgcca cgtgcttgca gccgaagccc atcgggcagg
    16261 tgcatgagct ggtcaggatc gaggcgccgt ccgcaaggcc ggattcctct tccacctcgg
    16321 cttcgacggt gtagggcgtg cgctggcgac ccttcaccag ggccgagacc gtgttgccct
    16381 cggcagagag cgcactgacc ctgctcacgt agcccaggcc cttggccacg gtctccacgc
    16441 cgagcgcggc gatcaggtcg tcctgggtga aggcttcgag gaggttcatc ggcgcgcggc
    16501 aggcccgagg cgggcatgaa cgggaaaacc cgatagttta tacgccagcc cgcagcgcac
    16561 gtgtgcggcg aatgggaaaa atgcgcgcgc gcaatgcaaa cgggccgcga tcgcggcccg
    16621 tcgtggttca cctcggggga gggtgcatca cacgttccga tacacctcgg ccccgccttt
    16681 cacgaactcc accgatttga cctccatgcc cttcttcagc gcctcggcct cgtcgatgcc
    16741 ctgctgggcg gcgaagtcgc gcacgtcctg ggtgatcttc atcgagcaga agtgcggacc
    16801 gcacatcgag cagaaatgcg ccaccttggc cgagtccttg ggcagggtct cgtcgtggaa
    16861 ttccttcgcc ttgtccgggt cgaggccgag gttgaactgg tcttcccagc ggaactcgaa
    16921 gcgcgccttg gagagcgcgt tgtcgcggat ctgcgcgccc gggtggccct tggcgaggtc
    16981 ggcggcgtgg gcggcgagct tgtaggtgat gatgccttcc ttgacgtcct gcttgttggg
    17041 caggcccaga tgctccttgg gcgtcacgta gcacagcatc gcggtgccgt accagccgat
    17101 ggtggctgcg ccgatgccgc tggtgatgtg gtcgtagccc ggggcgatgt cggtggtgag
    17161 cggccccagg gtgtagaagg gcgcctcctt gcaccactcg agctgcaggt ccatgttctc
    17221 cttgatgagc tgcagcggca cgtggcctgg gccctcgatc atgacctgca cgtcgtggcg
    17281 ccaggcgatc tcggtaagct cgccgagggt cttgagctcg cccagctgcg cctcgtcgtt
    17341 ggcatcgtag atcgaacccg ggcgcaggcc gtcgccgagg ctgaaggcca cgtcgtaggc
    17401 cttcatgatc tcgcagatgt cctcgaaatg ggtgtagagg aagctctcct tgtgatgcgc
    17461 caggcaccac ttggccatga tcgagccgcc gcggctgacg atgcc
//
LOCUS       DAOTIN010000062        17472 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_3923_length_17472_cov_9.139347, whole genome shotgun sequence.
ACCESSION   DAOTIN010000062 DAOTIN010000000
VERSION     DAOTIN010000062.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 17472)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 17472)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17472
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3923_length_17472_cov_9.139347"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            77..703
                     /gene="ccmA"
                     /locus_tag="P5537_10415"
     CDS             77..703
                     /gene="ccmA"
                     /locus_tag="P5537_10415"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004338923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis heme-transporting ATPase
                     CcmA"
                     /protein_id="HRV78495.1"
                     /translation="MLEVESLACLKGDRLLFRDLAFRLQAGGLLRVAGPNGVGKTSLL
                     RLVTGLALPEAGEIRWRGESIRRAREAFHGDLLYLGHAAALNDLLSPLENLRFACAAA
                     GDAVDEDDCVQALQRIGLADQLDLPARVLSQGQRRRVGLARLFLSNARPLWVLDEPFT
                     ALDVRAVADLAATLSQHCDAGGMVMLTTHQDAPFARPPEVLDVGVFAC"
     gene            697..1365
                     /gene="ccmB"
                     /locus_tag="P5537_10420"
     CDS             697..1365
                     /gene="ccmB"
                     /locus_tag="P5537_10420"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015232 - heme transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015886 - heme transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmB"
                     /protein_id="HRV78496.1"
                     /translation="MLSTFLAVLRRDLLLAWRGRADVLVTLAFFIIVVCLFPFGVGAE
                     PNQLRAIAPGVLWVAALLACLLSLHRLFAQDYSDGTLEQLLLSSEPAALWVMAKVLAF
                     WLSTGLPVVAVAPAMGLLLDLEQGGLPVLILSLLLGTPILALLGAVGAALTLGLRGGG
                     MLLALLVLPLFVPVLIFGAGAVEAELSGSGAAAHLLLLGGGLAGALALAPVACAAALR
                     ISTD"
     gene            1422..2207
                     /gene="ccmC"
                     /locus_tag="P5537_10425"
     CDS             1422..2207
                     /gene="ccmC"
                     /locus_tag="P5537_10425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015232 - heme transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015886 - heme transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter permease CcmC"
                     /protein_id="HRV78497.1"
                     /translation="MTNPERGRSLLRFAAPQNFYPLAGRLAPWFAALAVLLTAAGLWL
                     GFFVAPTDATQGQVYRVIFIHVPAAWMSMFIYVVMAFWSAVGLIMNTRLSFVMSQALA
                     PTGAMFCFVALWTGALWGKPTWGAYWVWDARLTSQLLLLFLYFGFIALTRAIEDPRRA
                     DRAGAIIALVGAVNVPIIYFSVQWWNTLHQGASVSLTKAPSMATTMLTGMLVMALASW
                     AYTLAVVLWRVRPMILERERHTEWVGAELERAGKLSQTAGGRA"
     gene            2207..2437
                     /gene="ccmD"
                     /locus_tag="P5537_10430"
     CDS             2207..2437
                     /gene="ccmD"
                     /locus_tag="P5537_10430"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015886 - heme transport [Evidence IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmD"
                     /protein_id="HRV78498.1"
                     /translation="MQQWESWSAFWDMGGAAFYVWGSYGLTFALIALELVLVFQRRKD
                     TTRRLLRWRRAVGKDAGKRNGEGTMPAMESET"
     gene            2434..2877
                     /gene="ccmE"
                     /locus_tag="P5537_10435"
     CDS             2434..2877
                     /gene="ccmE"
                     /locus_tag="P5537_10435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_process: GO:0017003 - protein-heme linkage [Evidence
                     IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c maturation protein CcmE"
                     /protein_id="HRV78499.1"
                     /translation="MKARSKRLMLVGGGVALLFAAVALVLSAFQQNLVFFHTPTEVSE
                     GKAPTGKTFRIGGMVEDGSIQREADGVTVRFAITDTAKVIPVTYKGTLPDLFKEGKGA
                     VVQGKLEGGVFRATEVLAKHDENYMPPEAAHAVEQAQKAAQTLSQ"
     gene            2879..4861
                     /locus_tag="P5537_10440"
     CDS             2879..4861
                     /locus_tag="P5537_10440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase CcmF/NrfE family subunit"
                     /protein_id="HRV78500.1"
                     /translation="MIPELGHFALILALVLSLVQAVVPLVGAHRNSSALMAVGRPAAQ
                     GQFFFILFSYVCLTWAFIQSDFSVQLAATNSHSATPLMYKITGVWGNHEGSLLLWAMS
                     LSLWTVAVTVFSRHLPDAFLARVLGVLGLVSAGFISFTLVTSNPFDRLLPAVAEGRDL
                     NPLLQDPGMIIHPPLLYMGYVGFSVAFAFAIAALLSGRLDAAWARWSRPWTTIAWVFL
                     TAGIAVGSGWAYYELGWGGWWFWDPVENASFMPWLLGTALMHSLAVTEKRGAFRSWTV
                     LLAIGAFSLSLLGTFLVRSGVITSVHAFATDPKRGLYILALLVIVIGFSLLLYAMRAN
                     KLMGGGSFGLVSRETSLLANNVLLTVASASVLLGTLYPLFLDALGLGKISVGPPYFEA
                     VFVPLMTPVVVLMMFGPFLRWKDDDLLAEVRRVAPAFVASVAIGVGGAWAVDHLTWRT
                     ALGLSLAAWVVLASLQLLARRLGERAGASAGSRLRSITASWWGMWLAHFGIGIFIIGV
                     TMVGSLDRHLDVKMKEGQHAELAGYTFVFRGAVDADGPNYDAARGNIELLRDGRSLDM
                     LTPEKRVYLAQGMPMTEASLDIGLFRDVYVSLGEQLEDGAWIVSLYYKPFISWIWAGC
                     VLMGLGGVFAAADRRYRRLAARDAAAAVDGRAGAAA"
     gene            4880..5473
                     /locus_tag="P5537_10445"
     CDS             4880..5473
                     /locus_tag="P5537_10445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbE family thiol:disulfide interchange protein"
                     /protein_id="HRV78501.1"
                     /translation="MKAKFLVPLLLFFGLAGFLAFGLTLNPREVPSPLIDKPAPNFRL
                     ARLDQPEQTFTLEDMRGQVWLLNVWASWCVACRQEHPLLVRMAEQKLVPVVGLAYKEV
                     RGDGAISTRGMSLEAETAMAVERGRRWLADHGNPYVVSVMDIDGRVGIDFGVYGVPET
                     FLIDREGRIRYKHIGPITPESLQTQIMPKVEELRRAG"
     gene            5463..6068
                     /locus_tag="P5537_10450"
     CDS             5463..6068
                     /locus_tag="P5537_10450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type biogenesis protein CcmH"
                     /protein_id="HRV78502.1"
                     /translation="MPADPKRSRSILSSLRRTLGVGALAVLMASPLHAATADAGPATV
                     PAGIATASDPGVAPAVAADPRLEADMMELSHKLRCLVCQNQSIAESNAPLAVDLRNQV
                     REQLAAGKDKDDVIDYLVERYGDFVLYEPPFNAATGLLWVGPFALLLAGAGWLAWRLR
                     RRRGEIAADGALSAADRERARALLAGGGDAASNPASPESRK"
     gene            6065..7288
                     /gene="ccmI"
                     /locus_tag="P5537_10455"
     CDS             6065..7288
                     /gene="ccmI"
                     /locus_tag="P5537_10455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="c-type cytochrome biogenesis protein CcmI"
                     /protein_id="HRV78503.1"
                     /translation="MTAFIVFAGLLVAGALLLILPPLLGYGRRSQAQARQSAMVLSVL
                     REQLAELDGELAEGRIDAAAHARSREELERRALDEAEVAAETADSADRRPRKAWALAT
                     GLTIPALAVGTYLMIGEPAALDPKNVEGQQGFTQEQVTEMVGSLEKHLVDNPDNAEGW
                     AMLARTYMVLKDFPKAAAAYARLDKLVPNNADVLSDWADVVAAQTGKVSGDAEALVLR
                     ALEAEPKHPKALALAGTAAYQRDDFAAAAGYWERILAQIPPGDDVGRGVRASIDEARA
                     KAGMAPLAAAEGNAAPAPSSPLKVAGRLQVDGALAGQVAAEDAVFVFVRGEAGGPPLA
                     ALRFKGSELPVSFDFDGAMLMMGDAPVPERIVVAARVSKGGDATARAGDLEGVSAPVA
                     PDADGVTVTIDRVRQ"
     assembly_gap    7396..7495
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(7506..8570)
                     /gene="alr"
                     /locus_tag="P5537_10460"
     CDS             complement(7506..8570)
                     /gene="alr"
                     /locus_tag="P5537_10460"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004386511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HRV78504.1"
                     /translation="MRPARALIDLAALRHNYRLARERHGGRALAVVKANAYGHGALRC
                     AQALCDEVDGFAVAFLGEALELRAGGIDAPILLLEGVFDAAELAEAARQRLWMVVHHE
                     EQVRMLERTPLAAPMDVWLKVNSGMNRAGFVGDAVARAWQRLQASGKVGRIVLMTHFA
                     RADEPDMETTLEQLQRFEAATAGLPGARSVANSAAILGWPQARRDWARPGILLYGADP
                     MPGEGNGLRAVMTLESAVMAVREIAPGEPVGYGGRFVAERPTRVGLVAMGYADGYPRV
                     VPDGTAVAVEGRASRIIGRVSMDMLTIDLTELPDAGLGSRVELWGAQVPVNRIAQAAG
                     TIAYELLCNVKRVGVEYVRR"
     assembly_gap    9082..9181
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<9182..10487)
                     /locus_tag="P5537_10465"
     CDS             complement(<9182..10487)
                     /locus_tag="P5537_10465"
                     /EC_number="1.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008718 - D-amino-acid dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0055130 - D-alanine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-amino acid dehydrogenase"
                     /protein_id="HRV78505.1"
                     /translation="MNVIVLGSGVIGTTTAWYLAQRGARVTVIDRQPGAALETSYANA
                     GQVSPGYSTPWAAPGIPLKAMKWLFQRHAPLAIRADGSLFQLRWMAQMLANCSSARYA
                     VNKERMMRVSEYARDCLRTLRADTGIAYEERSRGTLQLFRTQAQLDAAARDIAVLEEC
                     GVPYELLDGDALAAAEPALAHRPGKLAGGLRLPNDETGDCQLFTTRLAQMAEAAGVTF
                     RFGTEVRELVRRGGHIEGVRIAGADGVEQTLVADRYVLAFGSYSRALAASLGLDLPVY
                     PVKGYSLTVPLIDAARAPVSTVLDETYKVAVTRFDERIRVGGMAELGGFDLRLNPRRR
                     ETLEMVVNDLFPGGGDVKAAEFWTGLRPMTPDSTPIIGATPFPELFLNTGHGTLGWTM
                     SCGAGALVADLVTGRQPAIRHDDLALARYGAERRSMPTAGPRQ"
     gene            10621..11088
                     /locus_tag="P5537_10470"
     CDS             10621..11088
                     /locus_tag="P5537_10470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HRV78506.1"
                     /translation="MRDLDRTDLKILDLLQKNGRLTMTELAHQVGLSATPCTERVRRL
                     EREGVITGYHARVDPRALGRPLLVFVELKLAAKSNDAFERVKKELAFVPEVMECHLVS
                     GDFDYLIKARISEMSDYRRLLGNILLKLPSATESRSYVVMEEVKESLYIPSMS"
     gene            11129..11947
                     /locus_tag="P5537_10475"
     CDS             11129..11947
                     /locus_tag="P5537_10475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HRV78507.1"
                     /translation="MSAERGAPIRALERGIEVLRLLGPQEGSSLRALHAASALPKPTL
                     LRILHTLERGGLAWRSIEDGLWRRSQAWAAAPSGSAIDPRLVEASAPHLVALQRTVLW
                     PSDLLVYRDFAMEVAESSRRLSGLALNPRYGIGYRVDILLSAPGRAWLAFCDPAERAA
                     VIAHWRAASPPNPRTAAVLDGELDAILEETRRRGYAVRDALFGGSFEEMAGFDDGFDA
                     IAVPILADDGVRAAINLVWPRRYDLRAKVVEAHLGDLQACAAAIAAALASPRRP"
     gene            complement(11980..14028)
                     /locus_tag="P5537_10480"
     CDS             complement(11980..14028)
                     /locus_tag="P5537_10480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c3 family protein"
                     /protein_id="HRV78508.1"
                     /translation="MRLAALLLALVLMVPAAFAAVPQAGARPDHVADRDCLACHPDQA
                     GAWAESKHRHAMQPATAQTVLGDFGDVRFGEGAAAARFFRRGGDFVVAAQGADGRTQE
                     LAASHVFGIRPLQQVLLPQEGGRLQAFTIAWDTTRKTWFSLHTDGPVPPGDNLHWSGR
                     YQNWNLMCGECHTTAYRKGYDDEHDRYATTWAEPNVGCQACHGAGRAHAESAGRLAAT
                     GARAQRPVPTPNRALAGAHAQVDQCAACHARRTRLVEDAVAGAPLFDQFVPDNLRPGL
                     YHADGQQLDEVFEYGSYRQSRMYQAGVACTDCHDPHRGRLRADGNALCTACHNPTPDR
                     GRFPGLQPKDYDAPAHHFHRGGGAGSQCVDCHMPSRNYMVVHPRRDHAIRIPRPDLSA
                     RTGAPDACTGCHAERGAEWAAGAIERHHGKRTHPPHYGERLAAARAGTPGAAAGLAAL
                     AGDAALPAIVRASAIEQLAQLDPGALPAAALRDPDPAVRTSAAAAFALRPAEERVAQL
                     SPLLADPLRAVRITAARALADLPVAALAPTLQDRQRAALAEFIAAQQAMADMPSAQLN
                     LAGLALAQGDAPAAEQRLRRALQREPALDAARLGLATLLAQTRREDEAERVLRDGLAR
                     AASPGELHLALGLLAGQRQRWEEAARELRAADALLPGHARVRRNLDAVERYLERTRPR
                     "
     gene            complement(14033..15781)
                     /locus_tag="P5537_10485"
     CDS             complement(14033..15781)
                     /locus_tag="P5537_10485"
                     /EC_number="3.1.6.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HRV78509.1"
                     /translation="MKAALATLLIPVATLTIGIQAGHAAPPAKADRPNILLIMADDLG
                     YTDLGSYGSEIATPNLDKLADTGVKMTQFYASPFCSPTRAMLMSGTDNHLAGFGDMAE
                     LMLPEQRGKPGYEGYLNERVVPMAQVLRDAGYRTLMTGKWHLGVPEQFSPAARGFDQS
                     YALVHGGSSHWSDGAGIVAADPAKPPKAIYRENGKEATLPKDFFSSDFFTSRLIQYID
                     AGKDSGKPFFAYLAFTAPHWPLHAHDVDIAKYEGRYKDGYDKLRRDRLERMKKLGLVA
                     ADTPVFEGHPLWPKWDSLSAAEKESEARRMAVYAAMVDNMDQNVGRMLDYLKKTGQLD
                     NTFIFFLSDNGADGNSVYDVARTREWIHKDMDNSIAHIGKSGSYAEYGPGWAQVGSTP
                     FRMFKSFMYEGGIAVPAIAWGPGVKGGKLESAMAHVTDIAPTLFELAGTRHPGTEYQG
                     KPVLPLRGASMLPLLQGRGQAVHGADKAIGWELGGRKALRKGDWKIVSANQPWGTGDW
                     ELFNVAQDRTEGRNLAASNPQKLGEMLVAWRDYVRETGTLEIPNLANRPGYSNGAKYY
                     EDLKYEATLVPRTAKP"
     gene            16075..16779
                     /locus_tag="P5537_10490"
     CDS             16075..16779
                     /locus_tag="P5537_10490"
                     /inference="COORDINATES: protein motif:HMM:NF019225.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-CTERM sorting domain-containing protein"
                     /protein_id="HRV78510.1"
                     /translation="MKLHALALSLALSAMSMGAQAAVVGVYGGYPSSVSVSGGLTGLG
                     HSVVDVATADAASLAGLDALIIGRSQSGNAAITSFINGGGMLFTEWSTASYGMSLLGG
                     SASDNYGSSMTNDSVVFTAAGIAAGLGNVLGTSYADGGASEFFQDFGTLGSGTVFATR
                     GSSGAAAIVGGAYGSGYVWVNGFDWADGPGPNTFRLIDNQIDAQIGTGTVPEPATLLL
                     MGAGLLGAGFVRRRSA"
     gene            17140..>17472
                     /locus_tag="P5537_10495"
     CDS             17140..>17472
                     /locus_tag="P5537_10495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009401136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HRV78511.1"
                     /translation="MLQSKTTTAANLGGFIADAGLRVLLLDLDVQPTLSSYFTLDVRA
                     PGGIYEMLAFNERRIEQLVSRTAVAGLDLVLSNDDRGELNTLLLHAPDGRLRLRHLLP
                     VFRTHYDLL"
BASE COUNT         2261 a         6070 c         6199 g         2742 t
ORIGIN      
        1 gcgtgccgtg gggcgcgcct tgccgggatg cgccgggatg gcgcatcccg tgccgtctgt
       61 gttccaatcc gtccccatgc tcgaagtcga aagtctcgcc tgcctgaaag gcgatcgcct
      121 gcttttccgc gacctcgcct tccgcctgca ggcgggcggt ctgttgcgcg tcgccgggcc
      181 caacggggtg ggcaagacca gcctgctgcg cctggtcacc gggctggcgc tgcccgaggc
      241 cggcgagatc cgctggcgcg gcgagtcgat ccggcgcgcg cgcgaggcct tccacggcga
      301 cctgctctac ctcggccacg ccgccgcgct caacgacctg ctcagcccgc tcgagaacct
      361 gcgcttcgcc tgtgccgccg ccggcgacgc ggtggatgag gacgactgcg tgcaggccct
      421 gcagcgcatc ggcctggccg accagctcga cctgccggcg cgcgtgctgt cgcagggcca
      481 gcgccgccgc gtcgggctgg cccggctgtt cctgtcgaat gcgcgcccgc tgtgggtgct
      541 cgacgaaccc ttcacagcgc tcgacgtgcg cgcggtcgcc gatctcgccg ccaccctgtc
      601 gcagcattgc gacgcgggcg gcatggtgat gctcaccacc caccaggacg cgcccttcgc
      661 gcgcccgccc gaggtgctcg acgtcggggt cttcgcatgc tgagcacctt cctcgccgtg
      721 ctgcggcgcg acctgctgct ggcctggcgc gggcgcgccg acgtgctcgt cacgctcgcc
      781 ttcttcatca tcgtggtgtg cctgttcccc ttcggcgtcg gcgccgagcc caaccagctg
      841 cgcgcgatcg cccccggcgt gctgtgggtc gcggcactcc tcgcctgcct gctgtcgctg
      901 caccgcctgt tcgcgcagga ctacagcgac ggaactctcg agcagcttct cctgtctagc
      961 gagccggctg cgctgtgggt gatggccaag gtgctggcgt tctggctcag caccggcctg
     1021 ccggtggtcg cggtggcgcc ggccatgggc ctgctgcttg acctcgaaca aggcggcctg
     1081 cccgtgctga tactaagttt gctgctcggc acgcccatcc tcgcgctgct cggtgcggtc
     1141 ggtgcggcac tgaccctcgg cctgcgtggt ggtggcatgt tgctggccct gctggtgctg
     1201 ccgctgttcg tgccggtgct gatcttcggt gccggcgcgg tggaggccga gctgtcgggc
     1261 agcggcgccg cggcccacct cctgctgctc ggtggcggcc tggcgggggc gctcgcgctg
     1321 gcgccggtgg cgtgcgcggc ggccctcaga atttcaaccg attgacgacg ttgccgcgcc
     1381 ccgtgcgggt gcggcggacc gagaaggcga agcctcgaag catgacgaat cccgaacgcg
     1441 gccgcagcct gctgcggttt gctgcaccgc agaacttcta tcccctcgcc ggccgtctcg
     1501 caccctggtt cgcggcgctc gccgtcctcc tcaccgcggc cggcctgtgg ctcggcttct
     1561 tcgtcgcccc caccgacgcc acccagggcc aggtctatcg ggtgatcttc atccacgtcc
     1621 cggcagcctg gatgtcgatg ttcatctacg tggtcatggc cttctggtcg gcggtcgggc
     1681 tgatcatgaa cacgcgcctg tccttcgtga tgagccaggc gctcgcgccc acgggggcga
     1741 tgttctgctt cgtcgcgcta tggaccggcg cgctgtgggg caagcccacc tggggcgcct
     1801 actgggtgtg ggacgcgcgc ctgacctcgc agctgctgct tctcttcctt tacttcggct
     1861 tcatcgcgct cacccgcgcg atcgaggatc cgcgccgcgc cgaccgcgct ggcgccatca
     1921 tcgcgctggt gggcgcggtc aacgtgccga tcatctactt ctcggtgcag tggtggaaca
     1981 ccctgcacca gggcgcctcc gtgagcctca ccaaggcgcc gtcgatggcg accaccatgc
     2041 tcaccggcat gctggtgatg gcgctggcgt cgtgggccta caccctcgcg gtggtgctgt
     2101 ggcgggtgcg gccgatgatc ctcgagcgcg agcgccacac cgagtgggtc ggcgccgagc
     2161 tcgagcgcgc cgggaagctt tcgcaaaccg ccggaggtcg tgcctgatgc agcagtggga
     2221 gagctggtcc gcgttctggg acatgggcgg cgccgccttt tacgtgtggg gcagctacgg
     2281 cctcaccttc gcgttgatcg cgctggaact cgtgctcgtg ttccagcgtc ggaaggacac
     2341 cacccgccgc ctgctgcgct ggcgccgcgc ggtgggcaag gatgcaggca agcgtaacgg
     2401 cgaaggcacg atgcccgcca tggagtcgga aacatgaaag cccgtagcaa acgtctgatg
     2461 ctggtcggcg gcggggtggc cctgctgttc gccgcggtcg ccctggtgct gagcgccttc
     2521 cagcagaacc tggtgttctt ccacaccccg accgaggtct ccgagggcaa ggcgcccacc
     2581 gggaagacct tccgcatcgg cggcatggtc gaggacggct cgatccagcg cgaagccgac
     2641 ggtgtcacgg tgcgctttgc gatcaccgac accgccaagg tcatcccggt gacctacaag
     2701 ggcacgctgc ccgacctctt caaggagggc aagggtgcgg tggtgcaggg caagctcgag
     2761 ggcggcgtgt tccgcgccac cgaggtgctc gccaagcacg acgagaacta catgccgccc
     2821 gaggccgcgc acgcggtgga acaggcccag aaggccgcac agacgctgag ccagtgacat
     2881 gatccccgaa ctcggacact tcgccctcat cctcgccctt gtgctgtcgc tggtgcaggc
     2941 ggtggtgccg ctggtcggcg cgcaccgcaa cagctccgcg ctgatggcgg tcggccgccc
     3001 ggccgcgcag gggcagttct tcttcatcct gttcagctac gtctgcctga cctgggcctt
     3061 catccagagc gacttctcgg tccagctcgc ggccaccaac tcgcacagcg ccaccccgct
     3121 gatgtacaag atcaccggcg tgtggggcaa ccacgagggc tcgctgctgc tgtgggcgat
     3181 gtcgctgtcg ctgtggacgg tggcggtgac ggtgttctcg cgccacctgc cggacgcctt
     3241 cctcgcccgc gtgctgggcg tgctcgggct ggtcagtgcc ggcttcatct ccttcaccct
     3301 ggtcacctcc aaccccttcg accgcctgct gccggccgtc gccgaggggc gcgacctcaa
     3361 cccgctgttg caggacccgg ggatgatcat ccacccgccg ctgctctaca tgggctacgt
     3421 cggcttctcg gtggccttcg cgttcgcgat cgcggcactg ctctcgggcc ggctcgacgc
     3481 cgcctgggcg cgctggtcgc ggccgtggac cacgatcgcc tgggtcttcc tcaccgccgg
     3541 catcgcggtc ggctcgggct gggcctacta cgagctcggc tggggcggct ggtggttctg
     3601 ggatccggtg gagaacgcct cgttcatgcc ctggctgctc ggcaccgcgc tgatgcactc
     3661 gctcgccgtc accgagaagc gcggtgcctt ccgcagctgg acggtgctgc tggcgatcgg
     3721 cgccttctcg ctgtccctgc tcggcacctt cctcgtacgc tcgggcgtca tcaccagcgt
     3781 gcacgccttc gccaccgacc ccaagcgcgg cctctacatc cttgccctgc tcgtgatcgt
     3841 gatcggcttc tcgctgctgc tgtacgcgat gcgcgccaac aagctcatgg gcggcggcag
     3901 cttcgggctg gtgtcgcgcg agacctcgct gctcgccaac aacgtgctgc tcaccgtggc
     3961 ctcggcctcg gtgctgctcg gcacgctgta tccgctcttc ctcgacgccc tcggcctcgg
     4021 caagatctcg gtcggcccgc cctacttcga ggcggtgttc gtgccgctga tgaccccggt
     4081 ggtggtgctg atgatgttcg gccccttcct gcgctggaag gacgacgacc tcctcgccga
     4141 ggtgcgccgc gtcgcgccgg ccttcgtcgc cagcgtggcg atcggtgtcg gcggcgcgtg
     4201 ggcggtggat cacctcacct ggcgaaccgc gctcggcctg tcgctcgccg cctgggtggt
     4261 gctcgccagc ctgcagctgc tcgcccgccg cctcggcgag cgcgccggcg cctcggccgg
     4321 ctcgcgcctg cgctcgatca ccgcgtcgtg gtggggcatg tggctcgccc acttcggcat
     4381 cggcatcttc atcatcggcg tcaccatggt gggcagcctg gaccgccacc tcgacgtcaa
     4441 gatgaaggaa ggccagcacg cggagctcgc cggctacacc ttcgtgttcc gcggcgcggt
     4501 ggatgccgac ggccccaact acgacgccgc gcgcggcaac atcgagctcc tgcgcgacgg
     4561 ccgctcgctc gacatgctca ccccggagaa gcgcgtctat ctcgcccagg gcatgccgat
     4621 gaccgaggcc tcgctcgaca tcggcctgtt ccgcgacgtc tatgtctcgc tcggcgaaca
     4681 gctcgaggac ggcgcctgga tcgtcagcct ctactacaag cccttcatca gctggatctg
     4741 ggctggttgc gtgctgatgg gcctgggggg cgttttcgcc gccgccgacc gccgctaccg
     4801 ccgcctcgct gcgcgcgacg ccgctgcggc ggtggatggc cgtgccggcg ctgccgcctg
     4861 agttccgcct gggaaaacca tgaaagccaa gttcctcgtt ccgctgctgc tgttcttcgg
     4921 cctcgccggc ttcctcgcct tcggcctcac cctcaatccg cgcgaggtac cctcgccgct
     4981 gatcgacaag ccggcgccga acttccgcct cgcccgcctc gaccagcccg agcagacctt
     5041 cacgctcgaa gacatgcgcg gccaggtctg gctgctcaac gtgtgggcct cgtggtgcgt
     5101 cgcctgccgc caggagcatc cgctgctggt gcgcatggcc gagcagaagc tggtgccggt
     5161 ggtcgggctt gcctacaagg aggtgcgcgg cgacggtgcg atcagtacgc gtggcatgag
     5221 cctcgaggcc gagaccgcga tggcggtgga gcgcggccgg cgctggctgg ccgatcacgg
     5281 caacccctac gtggtgtcgg tgatggacat cgacggccgc gtcggcatcg acttcggcgt
     5341 gtatggcgtt cccgagacct tcctgatcga ccgcgagggc cgcatccgct acaagcatat
     5401 cggcccgatc acccctgagt cgctgcagac ccagatcatg cccaaggtcg aggagctgcg
     5461 ccgtgccggc tgatccgaag cgttcccgct ccatcctctc ctcgctgcgt cgcacgcttg
     5521 gcgtcggcgc gcttgccgtg ctgatggcct ccccgctcca cgccgccacc gccgacgccg
     5581 ggccggccac cgtgcccgct ggcatcgcca cggcgagcga tcccggcgtc gctcctgcgg
     5641 tcgccgccga tcccaggctc gaagccgaca tgatggagct gtcgcacaag ctgcgctgcc
     5701 tcgtctgcca gaaccagtcg atcgccgaat ccaacgcgcc gctggcggtg gacctgcgca
     5761 atcaggtgcg cgagcagctc gccgcgggca aggacaagga cgacgtgatc gactacctgg
     5821 tcgagcgcta cggcgacttc gtgctctacg agccgccctt caacgccgcg accgggctgc
     5881 tctgggtcgg gccgttcgcc ctgctgctgg cgggcgccgg ctggctggcc tggcgcctgc
     5941 gcaggcgccg cggcgagatc gccgccgatg gcgcgctcag cgccgcagac cgcgagcgcg
     6001 cgcgtgcgct gctcgccggc ggcggggacg ccgcctcgaa tcccgcttcc ccggagtccc
     6061 gcaagtgacc gccttcatcg tcttcgccgg cctgctcgtg gccggcgcgc tgctattgat
     6121 cctgcctccg ctgctcggct acggccgccg tagccaggcc caggcgcgcc agagcgccat
     6181 ggtgctcagc gtgctgcgcg agcagctcgc cgagctcgat ggcgaactcg ccgagggccg
     6241 catcgacgcc gccgcccacg ccaggagccg cgaggagctc gagcgccgtg ccctcgacga
     6301 ggccgaggtg gccgccgaga cggccgacag cgccgaccgc cggccgcgca aggcctgggc
     6361 gctcgccacc ggcctcacca tccccgcgct cgccgtcggc acctacctga tgatcggcga
     6421 gcccgccgcg ctcgacccca agaacgtcga gggccagcag ggcttcaccc aggagcaggt
     6481 caccgagatg gtgggcagcc tcgagaagca cctcgtcgac aaccccgaca acgccgaggg
     6541 ctgggcgatg ctggcacgca cctacatggt gctgaaggat ttccccaagg ccgcggccgc
     6601 ctacgcgcgc ctcgacaagc tggtccccaa caacgccgac gtgctgtccg actgggccga
     6661 cgtcgtcgcc gcgcagaccg gcaaggtgag cggcgacgcc gaggcgctgg tgctgcgcgc
     6721 gctcgaggcc gaaccgaagc atcccaaggc gctggcgctg gccggcaccg ctgcctacca
     6781 gcgcgacgac ttcgccgccg ctgccggcta ctgggaacgc atcctcgccc agattccccc
     6841 gggcgacgac gtcgggcgcg gcgtgcgcgc gagcatcgac gaggcgcgcg ccaaggccgg
     6901 catggccccg ctcgcggccg ccgaaggcaa cgccgcaccg gcaccgtcct ccccgctcaa
     6961 ggtcgccggc cgcctgcagg tcgacggcgc gctcgccggc caggtcgcgg ccgaggacgc
     7021 cgtgttcgtg ttcgtgcgcg gcgaggccgg cggtcccccg ctcgcggcgc tgcgcttcaa
     7081 gggcagcgag ctgccggtga gcttcgactt cgacggcgcg atgctgatga tgggcgacgc
     7141 ccccgtgccc gagcgcatcg tcgtcgcggc gcgcgtctcc aagggcggcg acgccaccgc
     7201 gcgcgcgggc gacctggagg gcgtcagcgc cccggttgcc cccgacgccg acggcgtgac
     7261 ggtgaccatc gatcgagtgc ggcagtgagg gcgtgagcag tgaggcgtga gggatgaggt
     7321 gcggatcgca cccgaacgca cacgccccag ggaacgcagg cggttcggtg tcgcagtctc
     7381 ttgcgcctga cgcctnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7441 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnncgcct
     7501 gacgcctaac gcctcacgta ctccacgccc acccgcttca cgttgcacag cagctcgtag
     7561 gcgatcgtgc cggcggcctg ggcgatgcgg ttgaccggca cttgagcgcc ccacagctcc
     7621 acccggctgc cgaggccggc gtcgggcagc tcggtgaggt cgatcgtcag catgtccatc
     7681 gacacccggc cgatgatgcg gctggcgcga ccttcgaccg ccaccgccgt gccgtcgggc
     7741 accacgcgcg ggtagccgtc ggcgtagccc atcgccacca ggccgacccg ggtcgggcgt
     7801 tcggcgacga agcggccgcc gtagccgacg ggttcgccgg gcgcgatctc gcgcaccgcc
     7861 atcaccgcgc tctccagcgt catcaccgcg cgcaggccgt tgccctcgcc cggcatcgga
     7921 tcggcgccgt agagcaggat gcccgggcgc gcccagtcgc ggcgtgcctg cggccagccc
     7981 aggatcgcgg cggagttggc tacgctgcgt gcgccgggca ggccggcggt ggcggcttcg
     8041 aagcgctgca actgctccag cgtggtctcc atatcgggct cgtcggcgcg cgcaaagtgc
     8101 gtcatcagca cgatacggcc gaccttgccg ctcgcctgca ggcgctgcca ggcccgcgcc
     8161 accgcgtcgc cgacgaagcc ggcgcggttc atgccgctgt tgaccttcag ccacacgtcc
     8221 atcggcgcgg cgagcggcgt gcgctccagc atgcgcacct gttcctcgtg gtggacgacc
     8281 atccacagcc gctggcgcgc cgcctcggcc agctccgccg cgtcgaacac gccctcgagc
     8341 agcaggatgg gggcatcgat gccgcccgcg cgcagctcca gcgcctcgcc gaggaaggcc
     8401 accgcgaagc cgtccacctc gtcgcacagc gcttgcgcac agcgcaacgc gccgtggccg
     8461 taggcgttgg ccttgaccac cgcgagcgcc cgcccgccgt ggcgctcgcg ggcgaggcgg
     8521 tagttgtgac gaagggcggc aaggtcgatg agggcgcggg cgggacgcat ggtcgtgatc
     8581 agaggcggtt aaaggacaaa atggtgcgtt gatttcctcg gcaccgcaat ccgccccacg
     8641 ggcgctcctg ctccggtgcg gcgaggcgga cgatgggccg gcggcgtgca ttcatgcatg
     8701 cacccggcgc cggcccgggc gcaaacgagg cgatggtcca tcgacgcgcg gccgtgtcgc
     8761 ccgcagcgct tgcacccgta ccggtaggag cgccggcagg cgcgaagcgg gcggtcggac
     8821 ggtccgacgc gcgtcgcaat ctccgccgcc gcattcgcgc ctgccggcgc tcctacatga
     8881 accggcgcgg gtccgggcgc gaggtgggta tcgggccggc ggcgtgcggc catggatgca
     8941 cccggcgtgg gtttgggcgt aagcggggcg acgggtcgtc gacgcgcggc cgtgtcgccc
     9001 gtagcgcttc cgcctgcacc tgtagcagcg ccggcaggcg cgaagcgggc ggtcggacgg
     9061 tccgacgcgc gtcgcaatct cnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9181 ngctggcggg ggccggcggt cggcatgctg cggcgctcgg cgccgtagcg cgccagggcg
     9241 aggtcgtcgt ggcggatcgc gggctggcgg ccggtgacga ggtcggcgac gagcgcgccg
     9301 gcgccgcagg acatggtcca ccccagggtg ccgtggccgg tgttgaggaa gagctcgggg
     9361 aagggcgtgg cgccgatgat cggggtggag tccggcgtca tcgggcgcag gccggtccag
     9421 aactccgccg ccttcacgtc gccgccgccg gggaagaggt cgttcaccac catctccagg
     9481 gtctcgcgcc ggcgcgggtt caggcgcagg tcgaagccgc cgagctcggc catgccgccg
     9541 acgcggatgc gctcgtcgaa gcgcgtcacc gccaccttgt aggtctcgtc gagcacggtg
     9601 gacaccggcg cgcgtgcggc gtcgatcagc ggcacggtga gcgagtagcc cttcaccgga
     9661 tacaccggca ggtccagccc gaggctggcg gcgagcgcgc gcgagtagct gccgaaggcg
     9721 agcacgtagc ggtcggcgac cagggtctgc tcgacgccgt cggcgccggc gatgcgcacg
     9781 ccctcgatgt ggccgccgcg gcgcacgagc tcgcgcacct cggtgccgaa gcggaaggtg
     9841 acgccggccg cctcggccat ctgcgccagg cgggtggtga agagctggca gtcgccggtc
     9901 tcgtcgttgg gcaggcgcag gccgccggcg agcttgccgg ggcgatgggc cagcgccggc
     9961 tcggcggcgg cgagggcgtc gccatcgagc aactcgtagg gcacgccgca ctcttccagc
    10021 accgcgatgt cgcgcgcggc ggcatcgagc tgggcctggg tgcggaagag ctgcaacgtg
    10081 ccgcggctgc gctcctcgta ggcgatgccg gtgtcggcgc gcagcgtgcg caggcagtcg
    10141 cgggcgtact cggagacgcg catcatgcgt tccttgttca ccgcgtagcg cgcgctcgag
    10201 cagttggcga gcatctgcgc catccagcgc agctggaaca ggctgccgtc ggcgcggatg
    10261 gcgagcgggg cgtggcgctg gaacagccac ttcatcgcct tcagcggaat gccgggcgcg
    10321 gcccagggcg tggagtagcc gggcgagacc tggccggcgt tggcgtagct ggtctcgagc
    10381 gcggcgccgg gctggcggtc gatcacggtg acgcgcgcac cgcgctgggc cagataccac
    10441 gcggtggtgg tgccgatcac gccgctgccg agtacgatca cgttcatttc gcgtctcctg
    10501 cctgtattcg atggaattgc ggcagtctaa tgaggctttg ctagcgaaag tcactaaact
    10561 gatatcgtta atcagtgaag aacaccaatc cggagcctgc cttcccggcg gcgtagtgaa
    10621 atgcgcgacc tcgaccgtac agacctgaaa atactggatt tgttgcagaa gaacgggcgc
    10681 ctgacgatga ccgaactggc ccatcaggtg gggctgtcgg cgaccccgtg caccgagcgg
    10741 gtgcgccgcc tggagcgcga gggcgtgatc accggttacc acgcccgcgt cgacccgcgt
    10801 gcgctcggcc gcccgctgct ggtcttcgtc gagctcaagc tggccgcaaa gtcgaacgac
    10861 gccttcgagc gcgtgaagaa ggagctcgcc ttcgtgcccg aggtcatgga gtgccacctg
    10921 gtgtcgggcg acttcgacta tctgatcaag gcgcgcatct cggagatgag cgactaccgc
    10981 cgcctgctcg gcaacatcct gctcaagctg ccctcggcca ccgagtcgcg cagctacgtg
    11041 gtgatggagg aggtgaagga gagcctctat attccctcca tgtcatgagc ccagcgaggt
    11101 ccgggatgga cgacaggaga cggcgcgcat gagcgcggaa cgtggcgccc cgatccgtgc
    11161 gctcgagcgc ggcatcgagg tgctccgcct gctcggcccc caggagggca gctcgctgcg
    11221 cgcgctgcac gctgccagcg cgctgcccaa gccgaccctg ctgcgcatcc tgcacaccct
    11281 ggagcgcggc gggctggcgt ggcggtcgat cgaggacggg ctgtggcggc gctcgcaggc
    11341 gtgggccgcg gcgcccagcg gcagcgccat cgatccgcgc ctggtcgagg cctcggcgcc
    11401 gcacctcgtc gcgctgcagc gcaccgtgct gtggccgtcc gacctgctcg tgtaccgcga
    11461 cttcgcgatg gaggtcgcgg agagctcccg ccgcctctcc gggctcgcgc tcaatccgcg
    11521 ctacggcatc ggctaccgcg tggacatcct gctctccgcg cccgggcggg cctggctggc
    11581 cttctgcgac ccggccgagc gtgccgccgt gatcgcccac tggcgcgccg cgtcgccgcc
    11641 caatccgcgc acggcggccg tcctcgacgg cgagctcgac gccatcctgg aggagacgcg
    11701 ccggcgtggc tacgcggtgc gcgacgcgct cttcggcggc tccttcgagg agatggcggg
    11761 cttcgacgac ggcttcgacg ccattgccgt gcccatcctg gccgatgacg gggtgcgcgc
    11821 ggcgatcaac ctggtgtggc cgcggcgcta cgacctgcgc gcgaaggtgg tggaggcgca
    11881 cctgggcgac ctgcaggcct gcgccgcggc gatcgcggct gcgctcgcgt cgccgcgccg
    11941 gccctgagcc ttcgcccgcg ccgtcgcgcg ggccttcctt cagcgtgggc gggtgcgttc
    12001 caggtagcgc tccaccgcgt cgaggttgcg gcgcacgcgc gcatggccgg gcagcagcgc
    12061 gtcggcggca cgcagctcgc gcgcggcctc ttcccagcgc tggcgctggc cggcgagcag
    12121 gccgagggcg aggtggagct cgccgggact ggcggcgcgc gccagcccgt cgcgcaggac
    12181 gcgttcggcc tcgtcctcgc gccgggtctg cgcgagcagc gtggccagcc ccaggcgggc
    12241 cgcgtcgagc gcgggctcgc gctgcagcgc gcggcgcaag cgctgctctg cggcgggcgc
    12301 atcgccttgc gcgagcgcga gcccggcgag gttgagctgg gcgctgggca tatcggccat
    12361 cgcctgctgt gccgcgatga actcggccag cgcggcgcgc tgccgatcct gcagcgtggg
    12421 cgcgagcgca gccacgggca ggtcggcgag cgcgcgcgcc gcggtgatgc gcaccgcgcg
    12481 caaggggtcg gcgagcaggg gggagagctg cgcgacgcgc tcttcggcgg ggcgcagcgc
    12541 gaaggcggct gcggcgctcg tgcgcaccgc cgggtcgggg tcgcgcaggg cggcggccgg
    12601 tagcgcaccg gggtcgagct gggcaagctg ctcgatcgcg ctcgcacgca cgatcgcggg
    12661 cagggcagca tcgccggcga gcgcggccag gcccgccgcg gcgccggggg tgcccgcgcg
    12721 cgcggcggcg aggcgctcgc cgtaatgggg cggatgcgtg cgcttgccat ggtggcgctc
    12781 gatcgccccc gcggcccact ccgcgccgcg ctcggcgtgg cagccggtgc aggcgtcggg
    12841 ggcgccggtg cgcgcgctca ggtcggggcg cggaatgcgg atggcgtggt cgcggcgcgg
    12901 atgcacgacc atgtagttgc ggctcggcat gtggcagtcg acgcactggc tgccggcgcc
    12961 gccgccgcgg tggaagtgat gcgcgggcgc gtcgtagtcc ttcggctgca ggccgggaaa
    13021 gcgtccgcgg tcgggcgtgg ggttgtgaca tgcggtgcac agcgcgttgc cgtcggcgcg
    13081 caggcggccg cggtgggggt cgtggcagtc ggtgcaggcc acgcccgcct ggtacatgcg
    13141 gctctggcgg taggagccgt actcgaagac ctcgtcgagc tgctggccgt cggcgtggta
    13201 gaggccgggg cgcaggttgt cggggacgaa ctggtcgaac aggggggcgc cggccacggc
    13261 gtcctcgacc agccgggtgc ggcgtgcgtg gcaggcggcg cactggtcga cctgggcgtg
    13321 cgcgccggcc agcgcccggt tcggggtcgg tacgggccgc tgcgcgcgcg cgcccgtggc
    13381 ggcgagcctg ccggcgctct ccgcgtgcgc gcggccggcg ccgtggcagg cctggcagcc
    13441 cacattcggc tcggcccagg tggtggcgta gcggtcgtgc tcgtcgtcgt agcccttgcg
    13501 gtaggcggtg gtgtggcact cgccgcacat caggttccag ttctggtagc gcccgctcca
    13561 gtgcaggttg tcgcccgggg gcaccgggcc atcggtgtgc agcgagaacc aggtcttgcg
    13621 ggtggtatcc caggcgatcg tgaaggcctg caggcgcccg ccctcctgcg gcagcagcac
    13681 ctgctgcagc ggccggatgc cgaagacgtg gctggccgcg agctcctgcg tgcggccgtc
    13741 ggcgccctgc gcggcgacca cgaagtcgcc gccgcggcgg aagaaacgcg ctgccgccgc
    13801 gccctcgccg aaacgcacat cgccgaagtc gccgagtacg gtctgcgccg tcgccggctg
    13861 catcgcatgg cggtgcttcg attccgccca cgcgcccgcc tggtccgggt ggcaggcaag
    13921 gcagtcgcgg tcggcgacgt ggtcgggccg cgcccccgcc tgcgggaccg ccgcgaacgc
    13981 ggccggcacc atcaggacga gggcgaggag cagggcggcc aggcgcatgc gctcagggct
    14041 tggccgtgcg cgggacgagg gtagcctcgt acttcaggtc ctcgtagtac ttggcgccgt
    14101 tgctgtagcc gggacggttg gcgaggttgg ggatctccag cgtgccggtc tcgcgcacgt
    14161 agtcgcgcca ggccaccagc atctcgccca gcttctgcgg gttggaggcg gcgaggttgc
    14221 ggccctcggt gcggtcctgg gcgacgttga acagctccca gtcgcccgtg ccccagggct
    14281 ggttcgcgga cacgatcttc cagtcgccct tgcgcagcgc cttgcgcccg ccgagttccc
    14341 agccgatcgc cttgtcggcg ccatgcacgg cctgcccgcg gccctgcagc agcggcagca
    14401 tcgaggcgcc gcgcagcggc agcacgggct tgccctggta ctcggtgccc gggtgccggg
    14461 tgccggcgag ctcgaacagc gtcggcgcga tgtcggtcac gtgggccatg gccgactcga
    14521 gcttgccacc cttgacgccc gggccccagg cgatcgccgg cacggcgatg ccgccctcgt
    14581 acatgaagga cttgaacata cggaacggcg tcgagcccac ctgcgcccaa cccgggccgt
    14641 actcggcgta ggagccggac ttgccgatgt gcgcgatgct gttgtccatg tccttgtgga
    14701 tccactcgcg ggtgcgcgcc acgtcgtaca ccgagttgcc gtcggcgccg ttgtcggaca
    14761 ggaagaagat gaaggtgttg tcgagctggc cggtcttctt caggtagtcg agcatgcggc
    14821 cgacgttctg gtccatgttg tcgaccatcg cggcgtacac cgccatgcgc ctggcttcgg
    14881 actccttctc cgccgcgctc aggctgtccc acttcggcca cagcggatgg ccctcgaaca
    14941 cgggcgtgtc ggcggccacg aggccgagct tcttcatgcg ctcgaggcgg tcgcggcgca
    15001 gcttgtcgta gccgtccttg tagcgacctt cgtacttggc gatgtccaca tcatgggcgt
    15061 gcagcggcca gtgcggcgcg gtgaaggcga ggtaggcgaa gaagggcttg cccgaatcct
    15121 tgccggcgtc gatgtactgg atcagccgcg aggtgaagaa gtcggacgag aagaagtcct
    15181 tcggcagcgt cgcctccttg ccgttctcgc ggtagatggc cttgggcggc ttggccggat
    15241 cggcggcgac gatgcctgca ccgtcgctcc agtggctgga gccgccatgc accagggcgt
    15301 aggactggtc gaagccgcgc gcggccgggc tgaactgctc gggcacgccg agatgccact
    15361 tgccggtcat cagcgtgcga tagccggcgt cgcgcagcac ctgcgccatc ggcaccacac
    15421 gctcgttgag gtagccctcg tagcccggct tgccgcgctg ctcgggcagc atgagctcgg
    15481 ccatgtcgcc gaagccggcg agatggttgt cggtgccgga catcagcatc gcccgcgtcg
    15541 gcgagcagaa cggcgaggcg tagaactggg tcatcttgac cccggtgtcg gccagcttgt
    15601 ccagattggg ggtggcgatt tcgctgccgt agctgccgag gtcggtgtag ccgaggtcgt
    15661 cggccatgat cagcaggatg ttggggcggt ccgccttggc cggtggggcg gcgtggccgg
    15721 cctggatgcc gatggtgagc gtggccaccg ggatcagcag tgtcgcgagc gctgctttca
    15781 ttgtctgtct cctggaataa atccggcttg tatccggttt catgaattta attcaattct
    15841 cgagaaattc agcgcgatct gaagatgttc cgcagggtgg aacgatagcc tgcctccagg
    15901 cggcgtgtgc cgatgcgggc ggggcggacg gaaagcgtgt cggcagtctt tacacatgac
    15961 ccccggcaag cgtcctggcg acggacaagg tattgatctg gaagggaagg gaagggaagg
    16021 gaagggaagg cattgaactt gctccgatgc gctgacctaa ccaaggagcc aatcatgaag
    16081 ctgcatgcac tcgccctctc ccttgcgctc tccgccatgt cgatgggggc gcaggccgcc
    16141 gtcgtcggcg tgtatggggg ctatccctcg agcgtgtccg tatccggcgg tctcaccggc
    16201 ctggggcatt ccgtggttga cgtggccact gccgacgcgg ccagcctggc cggcctggat
    16261 gcgttgatca tcgggcgcag ccaaagcggc aatgccgcca tcaccagctt catcaacggc
    16321 ggcggcatgc ttttcaccga gtggagcacc gcctcgtacg gcatgagcct gctcggcggc
    16381 agcgcaagcg acaactacgg ctcctctatg accaacgaca gcgtcgtctt cactgcagcc
    16441 ggcattgctg cggggcttgg taacgtcttg gggacgagct atgcggatgg cggggcgagc
    16501 gagttcttcc aggacttcgg gaccctgggc agtggcaccg tcttcgcaac gcgcggttcg
    16561 agcggcgcag ctgcgatcgt gggcggtgcg tacggtagcg gctacgtctg ggtcaatggt
    16621 ttcgactggg ccgacggtcc ggggccgaac accttccgcc tgatcgacaa ccagatcgat
    16681 gcgcagattg gaaccgggac cgtccccgag ccggctaccc tgctgctgat gggcgccggc
    16741 ctccttggtg ccggcttcgt gcgccgtcgt tcggcctgag ggaccgaagc cagcgccggg
    16801 ccagcgtccg gcggcgcgac cgccggcgag cccttcactc cggggcgagg tcatccgcca
    16861 gaggctgagc ctgctcttca tcgaggacga cgaggcgcag aaccggcccg gcatcgtgcg
    16921 caccatctac gacctcaccg cgggcaccgg cggcatggtg ctcaatggct cgtcgtattc
    16981 accggcggtg ctggctcggg cgagtccgag atccgccgcc acccgttcga caacgagctg
    17041 gtcgcggccg ctggcggaga tcggcgcgga cctcgagcgt tcgatggccc ggagctgccg
    17101 atcgctttca acaccttgtc cagtgcgtcg aacgaggcga tgcttcagag caagaccacg
    17161 acggccgcca acctgggcgg cttcatcgcc gatgccgggc tgcgcgtgct gctgctggac
    17221 ctggacgtgc agcccacgct gtcgagctac ttcacgctgg acgtgcgcgc gcccggcggc
    17281 atctacgaga tgctggcctt caacgagcgg cgcatcgagc aactggtgtc gcgcaccgcg
    17341 gtcgcgggcc tggacctggt gctctccaac gacgaccgcg gcgaactgaa cacgctgctg
    17401 ctgcacgctc cggatgggcg cctgcgactg cgccatttgc ttcccgtctt ccgcacgcac
    17461 tatgacttgc tg
//
LOCUS       DAOTIN010000063        17465 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_3925_length_17465_cov_8.914819, whole genome shotgun sequence.
ACCESSION   DAOTIN010000063 DAOTIN010000000
VERSION     DAOTIN010000063.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 17465)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 17465)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17465
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3925_length_17465_cov_8.914819"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..206
                     /locus_tag="P5537_10500"
     CDS             <1..206
                     /locus_tag="P5537_10500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004265811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="aconitase family protein"
                     /protein_id="HRV78512.1"
                     /translation="GFEWREPGCSMCLAMNADRLEPGERCASTSNRNFEGRQGAGGRT
                     HLVSPAMAAAAAVTGRFTDVRAL"
     gene            235..363
                     /locus_tag="P5537_10505"
     CDS             235..363
                     /locus_tag="P5537_10505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009636 - response to toxic substance
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="entericidin A/B family lipoprotein"
                     /protein_id="HRV78513.1"
                     /translation="MKKLALIAAALVAGFVSMACNTVQGVGRDIEAGGEAIQRAVK"
     gene            363..1001
                     /gene="leuD"
                     /locus_tag="P5537_10510"
     CDS             363..1001
                     /gene="leuD"
                     /locus_tag="P5537_10510"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HRV78514.1"
                     /translation="MNPFTQLDGLVAPLDRANVDTDAIIPKQFLKSIKRSGFGPNAFD
                     EWRYLDVGQPGQDNSTRPLNPDFVLNQTRYQGAQILLTRDNFGCGSSREHAPWALEDY
                     GFRVLIGPSFADIFFNNSFKNGLLPIKLDAAEVDELFRQCEASVGYRLKVDLAAQTIT
                     RPDGRSIAFDIDPFRKECLLNGWDDIGLTLRHADKIRAFEDRRRAEHPYYFA"
     gene            1038..2102
                     /gene="leuB"
                     /locus_tag="P5537_10515"
     CDS             1038..2102
                     /gene="leuB"
                     /locus_tag="P5537_10515"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011286629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HRV78515.1"
                     /translation="MKICVLPGDGIGPEIMAQAVRVLNALDLKFEMEEALVGGCAVDA
                     TGNPLPEATLDLARAADAILLGAVGGPKWDNHPRNQRPELGLLGIRKELALFANLRPA
                     ILYPELANASTLKPEIVAGLDILIVRELTGDIYFGQPRGIELREVNGETQRVGWNTMI
                     YAEYEIRRILRVAFEAAMKRGKRLCSVDKMNVLETTQLWRDIAIEVSKDFPEVELTHM
                     LVDNAAMQLVRAPKQFDVMVTGNMFGDILSDEASMLTGSIGMLPSASLNADNKGMYEP
                     SHGSAPDIAGKDLANPLATILSAAMMLRYTFNQEEAAQRIERAVKKVLAEGYRTGDIF
                     EPGTKRVGTREMGDAVLAAL"
     gene            2157..3290
                     /gene="asd"
                     /locus_tag="P5537_10520"
     CDS             2157..3290
                     /gene="asd"
                     /locus_tag="P5537_10520"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HRV78516.1"
                     /translation="MNRVGLVGWRGMVGSVLMQRMVEEGDFAFIEPVYFSTSNAGGKA
                     PSFGGKEAAAPLQDAMNIDALKSCDIVITCQGGDYTKEVFPKLRATGWNGHWIDAASA
                     LRMNDDAVIILDPVNRNVIDAALAKGGRNWIGGNCTVSLMLMGLGGLFRYGLVEWISA
                     MTYQAASGAGAQNMRELISQMGTIHDSVKDLLADPASAILEIDRKVAETMRSDAFPKK
                     NFRNTPLAGSLIPWIDVPVEHGQSKEEWKGGAECNKILGNPAFRTPGSIPIDGLCVRI
                     GAMRCHSQALTIKLKKDVPLDELTEIIAGANDWVKVVPNDRETTERELTPTAVTGTLT
                     VPVGRLHKMAMGPEYLGAFTVGDQLLWGAAEPLRRMLRILLER"
     gene            3497..>4750
                     /locus_tag="P5537_10525"
     CDS             3497..>4750
                     /locus_tag="P5537_10525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FimV/HubP family polar landmark protein"
                     /protein_id="HRV78517.1"
                     /translation="MTKSVRASLLALSIAALPLSVQAAGLGQINVLSGLGQPLRAEIQ
                     ISANAQELQSLSARIASADAFRRANLSYGPAVSAIRVSVDTRAARPVVRLSSDRPIND
                     PFVDLLVELDWAGGNLVREYTFLLDPVELSAPRPLAAPIQAPAARPARAVPRSTVAAP
                     TRALPAERAPVDTWTVRRGDTMHRIASANAHPGTTLDQMLIALLRANPQAFDGGNINR
                     LRAGAVLNVPAADAVRAIDAGEARREIRAQAADFDAYRRGLATSVAGRAPTPAAAAAQ
                     ESGGRIVPRVQEAAAPTDAGDKVTVSRSDTGADASGEARLQVLEEELATRSRALEEAN
                     ERLVQLERSIRDLQRLLEVQSGTMGQLQASAGAPSGAAAVAEAPAAAQVVEAPAAREP
                     APAAPAPAPQEPAPVAAAAAPAPAPA"
     assembly_gap    4751..4850
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <4851..6686
                     /locus_tag="P5537_10530"
     CDS             <4851..6686
                     /locus_tag="P5537_10530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FimV/HubP family polar landmark protein"
                     /protein_id="HRV78518.1"
                     /translation="PAPAASTPAPAAVPAPPAATKPPAAAPAAPPAAPSFIDTLVQEP
                     SVLYGGAGILALLLAYAGLKARQRRKEEEVRAAEAALGAASVGTGGQSVFAGTGGQSV
                     DTGATSIMHTDFSHSGLSAIDADEGVDPVAEADVYMAYGRDAQAEEILQDALKADPAR
                     AAIHLKLLEIYAQRRNDRQFETVASELFARTGGQGRDWEKAAALGRRLDPENPLYAAE
                     PAEAVTQRAPQGEPAVAAAAAGAAAAGAVAASAAAAPTGPELASLDFTAAAAAQPSHS
                     QMRDTWTLPGELNKLAAGEREGEPAAGGGATGEGASAAPLADEIPFDTGALDFELDLA
                     DETPTAMPDLSATTPGLEREFDLTLEPAEEEPSDLPPATIPESLPASMPADDGALTFD
                     LDLGEPDESVAAAPAAPQPAVPVAPEAFASTPTISVEDSGTISSLDFELPGMEAPSGE
                     AFDLDATVISATGTLDDEPAPPPAAKADEAVVDLEKTAFDSSLLDFDFELDAPAPAAN
                     SAMPAGLDLTSIDLDLEAPPVDPGAAFDAVPFSVADTQFDQPAAGGAEEAGPVNEEAE
                     TKLELARAYEEMGDKEGALELLEEVVAEGTPRQQATARDMIARLG"
     gene            6746..7363
                     /locus_tag="P5537_10535"
     CDS             6746..7363
                     /locus_tag="P5537_10535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CbiQ family ECF transporter T component"
                     /protein_id="HRV78519.1"
                     /translation="MHSGLVLLLWLAAVAAVQLLPPLALGVAVAACALAAAALARART
                     WRLVRRIRVLLIAITVLFAWFTPGEAALLDWPRLGPTREGLALAALHAGRLLAVVCAV
                     GILLERLPLARLVGGLYALSRPLRLAGVDPERLALRLLLVLRYVDASPRGQGPVDWRH
                     WLADESPSDAAAEAAPVVLARERLGPGEGLLAGALFGALLWWSLA"
     gene            7360..8157
                     /gene="truA"
                     /locus_tag="P5537_10540"
     CDS             7360..8157
                     /gene="truA"
                     /locus_tag="P5537_10540"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HRV78520.1"
                     /translation="MKRIVLGLEYAGDAFCGWQSQAHGRTVQDVLERALAQIAGEPVR
                     THCAGRTDTGVHASAQVVHFDTGAERPASAWVRGVNALLPPAVVVRWSTEVADDFHAR
                     FLACERQYRYILHNAPTRPAMLAGRVGWYHLPLEVARMAAAAECLVGTHDFSSFRAAG
                     CQAKTPVRVMHEARVVRQGEYLLFDFRANGFLHHMIRNLVGALVYVGKGRYPVEWMRE
                     LLEARDRAHAAPTFSPDGLYLCGVAYPPRWPLPGDGRIIALPQLPLV"
     gene            8158..8781
                     /locus_tag="P5537_10545"
     CDS             8158..8781
                     /locus_tag="P5537_10545"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004640 - phosphoribosylanthranilate
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HRV78521.1"
                     /translation="MTRTRIKICGLTRPQDVRAAVASGADAIGFVFYPPSPRAVSIEQ
                     AAELVALLPPFVVSVGLFVNPAPGEVKTVLARVPLQLLQFHGDESESDCARHGRAWIK
                     AARMRPGVDLLEFAASYPRASGILVDAFVDGYGGGGKTFDWTLIPAGFTRPLVLSGGL
                     DADNVGDAVRRIRPWAVDVSSGVESAKGIKDADMIAAFIAGVRHADG"
     gene            8768..9979
                     /gene="trpB"
                     /locus_tag="P5537_10550"
     CDS             8768..9979
                     /gene="trpB"
                     /locus_tag="P5537_10550"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HRV78522.1"
                     /translation="MQMADTPYQFPDASGHFGPYGGIFVAETLMPALAELREAYAACQ
                     NDPEFIAEFEYELKHYVGRPSPIYHARRWSELLGGAQIYLKREDLNHTGAHKVNNCIG
                     QAMVARRMGKPRVIAETGAGQHGVATATVAARYGMECVVYMGSEDVKRQAANVYRMKL
                     LGATVVPVESGSKTLKDALNEAMRDWVTNVADTFYIIGTVAGPHPYPMMVRDFQSVIG
                     KECLVQMPDMVGRQPDYVIACVGGGSNAMGIFHPYIGVPGVRLVGVEAAGDGLDTGRH
                     SASLTAGRPGVLHGNRTYLLQDEDGQIIETHSVSAGLDYPGVGPEHAWLKDTARAEYV
                     GITDAEALEAFHKLCRLEGIIPALESSHALAYAAKLAPTLPKDKILLVNLSGRGDKDM
                     HTVAERSGLQF"
     gene            10035..10856
                     /gene="trpA"
                     /locus_tag="P5537_10555"
     CDS             10035..10856
                     /gene="trpA"
                     /locus_tag="P5537_10555"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HRV78523.1"
                     /translation="MSRIQTVFQRLQADGRKALIPFVTAGFPAPELTLPLMNALVEGG
                     ADILELGVPFSDPMADGPTIQRASERALAQGMSLRKVLETVRAFRATNADTPVVLMGY
                     ANPIEAMGQERFVAAAHEAGVDGVLVVDYPPEECVSFAATAKAGGLDPIFLLAPTSGE
                     QRFADVARAGSGYIYYVSLKGVTGSAKLDVDEVARRIPEIRAAVGMPVGVGFGIRDAE
                     SAQRIGAVADAVVIGSRIIEEIENNPGEEVARVRDFMRPIRAALDALAAGKGAQA"
     gene            10853..11728
                     /gene="accD"
                     /locus_tag="P5537_10560"
     CDS             10853..11728
                     /gene="accD"
                     /locus_tag="P5537_10560"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004376424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HRV78524.1"
                     /translation="MSWFEKLIPPRIKRGDSSRSKSIPEGLWSKCEGCESVLYRSDLD
                     SNLGVCPKCGHHHRLRARRRLDQLLDTEGRVEIGAEVTPVDALKFKDSRKYPDRLSAA
                     AADTGEADAMVVMRGAIKTVPVVVACFEFDFLGGSMGSVVGERFVRGARAAFEERLPF
                     ICITASGGARMQEGLLSLMQMAKTTAAITRLSERRLPFITLLTDPTMGGVSASFAFMG
                     DVVVAEPNALIGFAGPRVIEQTVREKLPEGFQRAEFLLDKGAIDLIVDRRELRDRLAV
                     LLAMLNRQPADVVVG"
     gene            11728..13041
                     /gene="folC"
                     /locus_tag="P5537_10565"
     CDS             11728..13041
                     /gene="folC"
                     /locus_tag="P5537_10565"
                     /EC_number="6.3.2.12"
                     /EC_number="6.3.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004376423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tetrahydrofolate
                     synthase/dihydrofolate synthase"
                     /protein_id="HRV78525.1"
                     /translation="MAEQAGLPASLDGWLALLEQRHGQHIELGLERVAAVRARMQAES
                     DAVVITVGGTNGKGSCCAMLEGILLASGYRVGCYTSPHLLRYNERVRIDGKDVDDAAL
                     VAGFAAVEGARGDTALTYFEHGTLAAWQVFAAARPDVIILEVGLGGRLDAVNVFEPDC
                     ALVTSVAMDHMDYLGDTREAIGFEKAGIFRAGRPAVCGDPQPPASLVEHAAAIGAQLW
                     ISGRDFGFGGDRQQWGYWRYAQPPREGALVRRGGLAYPALRGANQLLNAAAVITVLEC
                     LRDRIPVSMQHVRQGLMLVELPGRFQVQPGRPSVVLDVAHNPQAAGVLADNLGNMGFY
                     PETWAVLGMLADKDVAGVVELMAGRVDHWLLADLPGPRGLSAEALAAKVRAVKEGADI
                     RCFPTPAEAYAAAQKLVAEDDRIVVFGSFLTVSDVLAAIKAARRG"
     gene            13051..13746
                     /locus_tag="P5537_10570"
     CDS             13051..13746
                     /locus_tag="P5537_10570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HRV78526.1"
                     /translation="MTEADSLEIKKRARRRLVGAIALALLAAIVLPMMMDEEPHPSIE
                     DIQVSIPDRDKAVAARRASAPESASAPVAVAVPEDDEVVAAEKPAAEKAPAAPDKPAP
                     AAAAAKPASPPAPATPPAAATPPRPPAPAATPEPRRPSADEEARLRALIEGKASPARG
                     DSYVLQIGAFSDAGKAAKLVDELRARGFPAYTERAGNVTRVRVGPVAGRAEADAAAAR
                     LKSAGHPAVLQAR"
     gene            13758..14249
                     /locus_tag="P5537_10575"
     CDS             13758..14249
                     /locus_tag="P5537_10575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004382241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HRV78527.1"
                     /translation="MTVFDYVFLGLLGFSALIGMWRGLVSEVMAVLAWAAALFAAWRY
                     NGEAAEVFTGMIVEPMWRQVAGGALVVVGVLILAALLRYLLRELLRAAGLGATDRFFG
                     ALFGIARGLAVAFVVVLIGGLAGVAKEPWWRDALFSAPLESAVIAAKPWLPAEVADKI
                     RFR"
     gene            14260..15795
                     /gene="purF"
                     /locus_tag="P5537_10580"
     CDS             14260..15795
                     /gene="purF"
                     /locus_tag="P5537_10580"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004382239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HRV78528.1"
                     /translation="MCGILGVVATSPVNQLLYDGLQVLQHRGQDAAGIATSEGGRFHM
                     HKGSGLVRDVFRTRNMRNLEGNWGIGHVRYPTAGSAYNAAEAQPFYVNSPFGLLLAHN
                     GNLTNSEALKREMFLSDLRHINTSSDSEVLLNVFAHELQAACKGLKIDEEAIFTAVAG
                     VHRRCRGAYAVVVMIAGYGLLAFRDPYGIRPLVIGRNDCEAGTEWLVASESVAVDVLG
                     FRLLRDVAPGEAVLVDTAGRFHSRQCAARTVHAPCMFEFVYLARPDSIIDGVSVYESR
                     MKMGEYLADKMRRTMPNVHIDVVIPIPDSSRPSAMQMADRLDLPFREGFVKNRYIGRT
                     FIMPGQATRRKSVRQKLNTIHQEFKGKSVLLVDDSIVRGTTSKEIVNMAREAGATRVY
                     LASAAPPVRYANVYGIDMPTRGELIASDRSEEEICREIGADGLIYQDLDDLKASVRAL
                     NPSLQFFETSCFDGQYVTGDITVEYLNGVENQRGEAKPGKNDHDDDGDGQLDLNLASD
                     AER"
     gene            15834..17018
                     /locus_tag="P5537_10585"
     CDS             15834..17018
                     /locus_tag="P5537_10585"
                     /EC_number="4.2.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004333468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA];
                     GO_process: GO:0071268 - homocysteine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-succinylhomoserine sulfhydrylase"
                     /protein_id="HRV78529.1"
                     /translation="MNRPLPPELHPDTLAVRAGTERTQFREHGEAMYLTSSFVFGSAA
                     QAAACFSGEEEGYVYARFSNPTVTAMQTRLAALEGGEDCVATASGMSAILSLAMATMQ
                     AGDHVVASNGLFGATQQLFGGILSKFGISTTFVPATDLDAWRAAITPRTRLFFTETPS
                     NPLTEVIDIAGVAAIARAAGVIFAVDNCFCTPALQRPLELGADVVVHSATKYLDGQGR
                     VLGGAVVGSKAVTDEVFKFLRTAGPTLSPFNAWVILKGLETLRIRMEAQSASALELAR
                     WLEAQPGVARVYYPGLESHPQHALAMRQQKSGGAIVSFDVKGGRDAAWKVVDATRLIS
                     ITANLGDTKSTITHPATTTHGRISAEARATAGIGDGLLRIAVGLEDIDDLKADLARGL
                     AS"
BASE COUNT         2581 a         6370 c         5900 g         2514 t
ORIGIN      
        1 ccggcttcga gtggcgcgag ccgggctgtt cgatgtgcct ggcgatgaac gccgaccgcc
       61 tcgagccggg cgagcgctgt gcctcgacct cgaaccgcaa cttcgagggc cgccagggcg
      121 cgggtgggcg cacgcatctg gtgagcccgg cgatggcagc tgccgccgcg gtcaccggcc
      181 gcttcaccga cgtgcgcgcg ctctgagcgg gcgttccgga cagaggagaa ggcaatgaag
      241 aaactcgcac tgatcgccgc cgcgctcgtc gccggcttcg tctccatggc ctgcaatacc
      301 gtgcagggcg tcgggcgcga cattgaagcg ggtggcgagg ccatccagag ggcagtgaaa
      361 taatgaatcc gtttacccag ctcgacggcc tggtcgcgcc gctcgaccgc gccaacgtcg
      421 acaccgacgc catcatcccc aagcagttcc tgaagtcgat caagcgcagc ggcttcggcc
      481 ccaacgcctt cgacgagtgg cgctacctcg acgtcggcca gcccgggcag gacaacagca
      541 cgcgcccgct caatcccgac ttcgtgctca accagacgcg ctaccagggc gcccagatcc
      601 tgctcacgcg cgacaacttc ggctgcggca gctcgcgcga gcacgcgccg tgggcgctcg
      661 aagactacgg ctttcgcgtg ctgatcgggc cgagcttcgc cgacatcttc ttcaacaaca
      721 gcttcaagaa cggcctgctg ccgatcaagc tcgacgccgc cgaggtcgac gagctgttcc
      781 gtcagtgcga ggcgagcgtg ggttaccgcc tgaaggtcga cctcgccgcg cagaccatca
      841 cccgcccgga cggcaggtcg atcgccttcg acatcgaccc cttccgcaag gaatgcctgc
      901 tcaacggctg ggacgacatc ggcctcacgc tgcgccacgc cgacaagatc cgcgccttcg
      961 aagaccggcg ccgcgccgaa cacccctatt actttgcctg agccggcccg gctcaccgaa
     1021 ccaaggaaaa cgattcgatg aagatttgcg tgctgccggg tgacggcatc ggtcccgaga
     1081 tcatggccca ggccgtgcgc gtgctgaacg cgctcgacct gaagttcgag atggaagagg
     1141 ccctggtggg cggctgcgcg gtggacgcca ccggcaaccc gctgcccgag gccacgctcg
     1201 atctggcgcg ggcggccgac gccatcctgc tcggcgcggt cggtggcccg aagtgggaca
     1261 accacccgcg caaccagcgc cccgaactcg gcctgctcgg catccgcaag gagctggcgc
     1321 tgttcgccaa cctgcgcccg gcgatcctgt atccggagct ggccaacgcc tccaccctca
     1381 agcccgagat cgtcgccggc ctggacatcc tgatcgtgcg cgagctcacc ggcgacatct
     1441 acttcggcca gccgcgcggc atcgagttgc gcgaggtcaa tggcgagacc cagcgcgtgg
     1501 gctggaacac catgatctac gccgagtacg agatccgccg catcctgcgc gtggccttcg
     1561 aggccgcgat gaagcgcggc aagcgcctgt gctcggtcga caagatgaac gtgctcgaga
     1621 ccacccagct gtggcgcgac atcgcgatcg aggtgagcaa ggacttcccc gaggtcgagc
     1681 tcacccacat gctggtcgac aacgccgcga tgcagctcgt gcgtgcgccc aagcagttcg
     1741 acgtgatggt caccggcaac atgttcggcg acatcctgtc cgacgaggcc tcgatgctca
     1801 ccggctcgat cggcatgctg ccctcggcct cgctcaacgc cgacaacaag ggcatgtacg
     1861 agccctcgca cggctccgcg cccgacatcg ccggcaagga cctcgccaac ccgctcgcca
     1921 ccatcctgtc ggcggcgatg atgctgcgct acaccttcaa tcaggaagaa gccgcgcagc
     1981 gcatcgagcg tgcggtcaag aaggtgctgg ccgagggcta tcgcaccggc gacattttcg
     2041 agccgggcac gaagcgggtg ggtacgcgcg agatgggcga cgcggtgctc gcggcgctgt
     2101 aagcttctgc gcctcaacag gtttttcgag aaacgtctga gtagagagtg atgaacatga
     2161 atcgagtcgg tctggttggc tggcgtggca tggtcggttc cgtgctgatg cagcgcatgg
     2221 tggaagaggg cgacttcgcc ttcatcgagc cggtgtattt ctccacctcg aacgccggcg
     2281 gcaaggcgcc gtccttcggc ggcaaggaag ccgccgcgcc gctgcaggac gcgatgaaca
     2341 tcgacgcgct gaagtcctgc gacatcgtga tcacctgcca gggcggcgac tacaccaagg
     2401 aagtcttccc caagctgcgc gccaccggat ggaacggcca ctggatcgac gccgccagcg
     2461 cgctgcgcat gaacgacgac gcggtgatca tcctcgaccc ggtcaaccgc aacgtcatcg
     2521 acgccgcgct cgccaagggc ggccgcaact ggatcggcgg caactgcacc gtgtcgctga
     2581 tgctgatggg cctgggcggc ctgttccggt acggcctggt cgagtggatc tcggcgatga
     2641 cctaccaggc ggcctcgggc gccggcgcgc agaacatgcg cgaactcatc agccagatgg
     2701 gcaccatcca cgactcggtc aaggacctgc tcgccgaccc ggcctcggcc atcctcgaga
     2761 tcgaccgcaa ggtcgccgag accatgcgct cggacgcctt cccgaagaag aacttccgca
     2821 acaccccgct cgccggcagc ctgatcccct ggatcgacgt gccggtcgag cacggccaga
     2881 gcaaggaaga gtggaagggc ggcgccgagt gcaacaagat cctcggcaac ccggctttcc
     2941 gcaccccggg ctcgatcccg atcgacggcc tgtgcgtgcg catcggcgcg atgcgctgcc
     3001 actcgcaggc gctcaccatc aagctgaaga aggacgtgcc gctcgacgag ctcaccgaga
     3061 tcatcgccgg cgccaacgat tgggtgaagg tcgtgcccaa cgatcgcgag accaccgagc
     3121 gcgagctcac cccgaccgcc gtcaccggca cgctgaccgt cccggtcggc cgcctgcaca
     3181 agatggcgat gggccccgag tacctcggcg ccttcaccgt cggcgaccag ctgctgtggg
     3241 gcgcggccga gccgctgcgc cgcatgctgc gcatcctgct cgagcgctga gcgcttcgcg
     3301 gcagtccggc aaggggggcg cgagcccccc ttttcgttgc ggactcgtgg cgaaacgcgg
     3361 tatttcttca cgccgggcgg gtacgaatca ggctcggcta atgcgatgca ggcccggaaa
     3421 tgctagattc ccaagccaga tacggcgaaa tcgaccgtga tgctccgttg cgggggaacg
     3481 agtcttgaaa tccaaaatga caaagtcggt cagggcttcc ctgctcgccc tctccatcgc
     3541 cgcgctgccg ctttcggtgc aggcggccgg gcttggccag atcaacgtcc tgagcggcct
     3601 gggccagccc ctgcgtgccg agatccagat ctcggccaac gcgcaggagc tgcagtcgct
     3661 gagcgcccgc atcgcttcgg cggatgcgtt ccggcgcgcg aacctgagct atggccccgc
     3721 ggtgagcgcg atccgtgtca gcgtggatac gcgggccgcg cgcccggtgg tgcgcctcag
     3781 cagcgaccgc ccgatcaacg accccttcgt cgacctgctg gtcgagctcg actgggcggg
     3841 tggcaacctg gtgcgtgaat acaccttcct gctcgacccg gtggagcttt ccgcgccgcg
     3901 cccgctcgcc gcgccgattc aggctccggc ggcacggccc gcgcgtgcgg tgccgcgctc
     3961 caccgtggcc gcgcccacgc gtgcgctgcc tgccgaacgt gcgcccgtcg acacatggac
     4021 ggtgcggcgt ggcgacacca tgcaccgcat cgcgagcgcg aacgcccacc ccggcaccac
     4081 cctcgaccag atgctgatcg cgctgctgcg cgcgaacccc caggccttcg atggcggcaa
     4141 catcaaccgc ctgcgcgccg gtgcggtcct caacgttcct gcggccgacg cggtgcgcgc
     4201 catcgatgcc ggcgaggcgc ggcgcgagat ccgtgcccag gctgccgact tcgacgccta
     4261 ccggcgcggc ctcgcgacct cggtcgccgg tcgcgcgccc acacccgcgg cggcggcggc
     4321 gcaggagagc ggcggacgga tcgtgccgcg cgtgcaggaa gcggccgcgc cgaccgatgc
     4381 gggcgacaag gtgaccgtct cgcgcagcga taccggtgcg gatgcgagtg gcgaggcgcg
     4441 cctgcaggtg ctcgaggaag aactggccac gcgctcgaga gcgctcgagg aggccaacga
     4501 gcgcctcgtc cagctcgagc gcagcatccg cgacctccag cgcctgctcg aggtgcagag
     4561 cggcaccatg ggccagctgc aggcgtcggc cggcgcgccg agcggggccg cggcggtcgc
     4621 cgaagcgcct gcggcagcgc aggtggtcga ggctcccgcc gcgcgggagc ccgcccccgc
     4681 tgccccggcg ccagcgccgc aggagcccgc gcctgtggcc gcagccgcgg cgcctgcacc
     4741 ggctccggct nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ccggctccgg
     4861 ctgcatcgac gcccgctccc gcagcggtgc ccgctccccc cgctgcgacc aagccgccgg
     4921 ccgctgcgcc ggctgcaccg ccggcagcgc ccagcttcat cgacacgctg gtgcaggaac
     4981 cgagcgtgct ctatggcggc gcaggcatcc tcgcgctctt gctcgcctac gccggcctca
     5041 aggcgcgcca gcgccgcaag gaggaagagg tacgagccgc cgaggccgcg ctcggcgccg
     5101 cctcggtggg tacgggtggg cagagcgtgt tcgccggcac cggcggccag agtgtcgaca
     5161 ccggcgcgac cagcatcatg cacaccgact tcagccactc cggcctgtcc gcgatcgatg
     5221 ccgatgaagg tgtcgatccg gtagccgagg ccgacgttta catggcctac ggtcgcgacg
     5281 cgcaggccga agagatcctg caggacgcgc tcaaggccga ccctgcccgc gccgccatcc
     5341 acctcaagct gctggagatc tacgcgcagc gccgcaacga ccgccagttc gagaccgtgg
     5401 ccagcgagct gttcgcgcgc accggcggcc aggggcgtga ctgggagaaa gccgcggcgc
     5461 tgggtcgccg gctcgacccc gagaatcccc tctatgccgc cgagcctgcc gaggccgtca
     5521 cacagcgcgc gccgcagggt gagccggcgg tggccgctgc ggcagcgggc gccgccgctg
     5581 caggcgcagt cgcggcttcc gccgctgccg cgccgacggg cccggagctg gcctcgctcg
     5641 acttcaccgc cgcagccgcc gcgcagccga gtcactcgca gatgcgcgac acctggacgc
     5701 tgcccggcga gctcaacaag ctcgccgcag gcgagcgcga gggcgagccc gcagcgggcg
     5761 ggggggcgac gggagagggg gcgtcggcgg cccctctggc cgacgagatc ccgttcgaca
     5821 ccggcgcgct cgatttcgag ctcgacctgg ctgacgagac gcccaccgcg atgcccgacc
     5881 tttcggcgac cacgcctggt ctcgagcgcg agttcgacct caccctggaa ccggcggagg
     5941 aggaaccttc cgacctgcct cccgcaacca ttcctgaatc ccttcctgct tccatgccgg
     6001 cggatgacgg cgcgctgacc ttcgacctcg acctgggtga gcccgacgag tccgtggcgg
     6061 ccgccccggc ggcaccgcag ccggctgtcc cggtcgcgcc cgaagcattc gcctccacgc
     6121 cgacgatctc ggtggaggac tccggtacga tcagcagcct cgacttcgag ctgcccggca
     6181 tggaggcccc gagcggcgag gccttcgatc tcgacgcgac cgtgatcagc gccaccggca
     6241 cgctcgacga cgagccggcg ccgccgcccg cggccaaggc cgacgaggcc gtggtcgatc
     6301 tcgagaagac ggccttcgac tccagcctgc tcgacttcga tttcgagctc gatgcgcccg
     6361 cgcccgcggc gaattccgcg atgccggccg ggctggacct gacctcgatc gatctcgacc
     6421 tcgaggcgcc tccggtcgat cccggtgccg ccttcgacgc cgtgccgttc tcggtcgccg
     6481 acacccagtt cgaccagccg gctgccggcg gtgcggaaga ggccgggccg gtgaacgagg
     6541 aggcggagac caagctcgag ctggcccgcg cctatgaaga gatgggcgac aaggaggggg
     6601 cgctcgagct gctcgaggaa gtggtcgccg agggcacgcc gagacagcag gccacggccc
     6661 gcgatatgat cgcgcgcctg ggctgatcgc ccccgccggc aggccgccac gagcgcgggc
     6721 tcgcggcggc cttttccgtt taccgatgca ctccggtctt gtcctgctcc tctggctcgc
     6781 ggcggtcgcc gccgtccagc tgctgccgcc gctcgcgctc ggcgtcgccg tcgcggcctg
     6841 cgcgctcgcg gccgccgcgc tcgcgcgcgc gcgcacctgg cgcctcgtgc ggcgcatccg
     6901 cgtgctgttg atcgcgatca ccgtgctctt cgcctggttc accccgggcg aggcggcgtt
     6961 gctcgactgg ccgcgcctgg ggccgacacg cgagggcctc gcgctcgcgg cgctgcatgc
     7021 cgggcggctg ctcgcggtgg tgtgtgcggt cggcatcctg ctcgaacgcc tgccgctggc
     7081 tcgcctggtc ggcggcctct atgcgctgtc gcgcccgctg cgtctggccg gcgtagaccc
     7141 cgagcgcctc gccctgcgcc tcttgctggt gctgcgctat gtcgatgcct cgccgcgcgg
     7201 gcagggcccg gtcgactggc gacactggct ggccgacgag tccccgtcgg acgccgccgc
     7261 cgaggccgcg ccggtggtgc tggcgcgcga gcgcctcgga ccgggcgagg ggctgctggc
     7321 cggcgcgctc ttcggtgcgc tgctgtggtg gagcctggca tgaagcgcat cgtgctcggc
     7381 ctcgaatacg ccggtgacgc cttctgcggc tggcagagcc aggctcacgg ccgcaccgtg
     7441 caggacgtgc tcgagcgcgc gctcgcgcag atcgcaggcg agccggtgcg cacccactgc
     7501 gccgggcgca ccgacaccgg cgtgcatgcg agcgcgcagg tggtgcattt cgataccggc
     7561 gcggagcgcc cggcctcggc ctgggtgcgc ggcgtcaacg cgctgctgcc gcccgccgtg
     7621 gtggtgcgct ggtcgaccga ggtggccgac gacttccacg cccgcttcct cgcctgcgag
     7681 cgccagtacc gctatatcct gcacaacgcg ccgacgcggc cggcgatgct cgccgggcgg
     7741 gtgggctggt accacctgcc gctcgaggtg gcgcgcatgg ccgccgccgc cgagtgcctg
     7801 gtcggcaccc acgatttttc cagcttccgc gccgccggct gccaggcgaa gacgccggtg
     7861 cgggtgatgc acgaggcgcg cgtcgtgcgc cagggcgaat acctgctgtt cgacttccgc
     7921 gccaacggtt tcctgcatca catgatccgc aacctggtcg gcgcgctggt gtacgtcggc
     7981 aaggggcgtt atccggtgga gtggatgcgc gagctgctcg aggcccgcga ccgcgcgcac
     8041 gcggcgccga ccttctcccc cgacgggctc tacctgtgcg gcgtggccta cccgccgcgc
     8101 tggccgctgc ccggtgatgg gcgtatcatc gcgctgcccc agctccccct cgtctgaatg
     8161 acccgtaccc gaatcaagat ctgcggcctg acccggccgc aggacgtgcg cgcggccgta
     8221 gcgagcggcg ccgacgcgat cggcttcgtc ttctacccgc ccagcccgcg cgcggtctcc
     8281 atcgagcagg ccgccgagct cgtcgcgctg ctgccgccct tcgtcgtctc cgtcggcctc
     8341 ttcgtgaatc ccgcgcccgg cgaggtcaag acggtgctcg cgcgcgtgcc gctgcaactt
     8401 ctgcagttcc acggtgacga aagcgagtcc gactgtgccc gtcacgggcg cgcgtggatc
     8461 aaggcggcgc gaatgcggcc cggggtcgat ctgctagaat ttgcggcttc gtacccgcgc
     8521 gcgagcggca tcctggtcga cgccttcgtc gacggctatg gcggcggggg caagactttc
     8581 gactggacgc tgatccccgc cggcttcacg cgtccgctcg tgctatcggg cggactcgac
     8641 gcggacaacg tgggcgacgc cgtgcgccgc atccgcccgt gggcggtgga tgtgtcgagc
     8701 ggagtcgaga gtgcaaaggg aatcaaggac gcggacatga tcgccgcgtt catcgccgga
     8761 gttcgacatg cagatggctg acacgcctta ccagtttccc gacgcgagcg ggcatttcgg
     8821 gccctacggc ggcatcttcg tcgccgagac cctgatgccg gcgctcgccg agctgcgcga
     8881 ggcctatgcg gcctgccaga acgatccgga gttcatcgcc gagttcgagt acgagctcaa
     8941 gcactacgtt ggccgtccga gcccgatcta ccacgccagg cgctggtcgg agctcctcgg
     9001 cggcgcgcag atctatctca agcgcgagga cctcaaccac accggcgcgc acaaggtgaa
     9061 caactgcatc ggtcaggcca tggtcgcgcg ccgcatgggc aagccgcgcg tgatcgccga
     9121 gaccggcgcc ggccagcacg gcgtcgccac cgccaccgtg gcggcgcgct acggcatgga
     9181 gtgcgtggtc tacatgggct cggaggacgt caagcgccag gccgccaacg tctaccgcat
     9241 gaagctgctc ggcgccaccg tggtgccggt ggagtcgggc tcgaagacgc tcaaggatgc
     9301 gctcaacgag gccatgcgcg actgggtcac caacgtcgcc gacaccttct acatcatcgg
     9361 caccgtcgcc ggcccgcacc cctacccgat gatggtgcgc gacttccagt ctgtgatcgg
     9421 caaggagtgc ctggtgcaga tgcccgacat ggtcggccgc cagcccgact acgtgatcgc
     9481 ctgcgtgggc ggcggctcca acgcgatggg catcttccat ccctacatcg gcgtgccggg
     9541 cgtcaggctc gtcggcgtcg aggccgccgg cgacggcctc gacaccggtc gccactcggc
     9601 ctcgctgacc gccggccgcc ccggcgtgct gcacggcaac cgcacctacc tgctgcagga
     9661 cgaggacggc cagatcatcg agacgcactc ggtctccgcc ggcctcgact atccgggcgt
     9721 gggccccgag cacgcctggc tcaaggacac cgcacgcgcc gagtatgtcg gcatcaccga
     9781 tgccgaggcg ctcgaggcct tccacaagct gtgccgcctg gagggcatca tcccggcgct
     9841 cgagtcctcg cacgcgctcg cctatgccgc caagctggcg cccaccctgc ccaaggacaa
     9901 gatcctgctg gtcaacctct ccgggcgcgg cgacaaggac atgcacaccg tcgccgagcg
     9961 ctccgggctc cagttctgaa cccgaatccg aacctgaagc gggccgctga tgcggcccgc
    10021 agtgtgatcg agacatgtcg agaatccaga ccgttttcca gcgcctccag gccgatggcc
    10081 gcaaggcgct gatccccttc gtcaccgccg gcttcccggc gcccgagctc accctgccgc
    10141 tgatgaacgc gctggtcgag ggcggcgccg acatcctcga gctcggcgtg cccttctccg
    10201 acccgatggc cgacggcccc accatccagc gcgcctccga gcgcgcgctc gcgcagggca
    10261 tgagtctgcg caaggtgctc gagaccgtgc gcgccttccg cgccaccaac gccgacacgc
    10321 ccgtggtgct gatgggctac gccaacccga tcgaggccat gggccaggag cgcttcgtcg
    10381 ccgcggcgca cgaggccggc gtcgatggcg tgctcgtggt cgactatccg cccgaggagt
    10441 gcgtcagctt cgccgccacc gcgaaggccg gcggcctcga ccccatcttc ctgctcgcgc
    10501 ccacctcggg cgagcagcgc ttcgccgacg tcgcgcgcgc cggcagcggc tacatctact
    10561 acgtctcgct caagggcgtg accggcagcg ccaagctcga cgtcgacgag gtcgcgcgcc
    10621 gcatccccga gatccgcgcc gcggtcggca tgccggtggg cgtgggcttt ggcatccgcg
    10681 acgccgagag cgcgcagcgc atcggcgcgg tcgccgacgc ggtggtgatc ggcagccgga
    10741 tcatcgagga gatcgagaac aacccgggcg aggaggtcgc gcgcgtgcgc gacttcatgc
    10801 gtccgatccg cgccgcgctc gacgcgctgg cagcgggcaa gggggcacag gcatgagctg
    10861 gttcgagaaa ctcatcccgc cgcgcatcaa gcgcggcgat tcgtcgcgca gcaagtcgat
    10921 ccccgaaggg ctgtggagca agtgcgaggg ctgcgagtcg gtgctgtacc gctccgacct
    10981 cgacagcaac ctcggcgtgt gccccaagtg cgggcaccat caccgcctgc gcgcacgccg
    11041 ccgcctcgac cagctgctcg acaccgaggg ccgcgtcgag atcggcgccg aggtcacgcc
    11101 ggtcgatgcg ctcaagttca aggactcgcg caagtacccc gaccgcctgt ccgccgccgc
    11161 tgccgacacc ggcgaggccg acgcgatggt ggtgatgcgc ggtgcgatca agaccgtgcc
    11221 ggtcgtggtc gcctgcttcg agttcgactt cctcggcggc tcgatgggct cggtggtggg
    11281 cgagcgcttc gtgcgcggcg cgcgcgcggc cttcgaggag cgtctgccct tcatctgcat
    11341 caccgcctcg ggtggcgcgc gcatgcagga aggcctgctg tcgctgatgc agatggccaa
    11401 gaccacggcg gcgatcactc gcctgtccga gcgccgcctg cccttcatca ccttgctcac
    11461 cgaccccacc atgggcggcg tgtcggcgag cttcgccttc atgggagacg tcgtcgtcgc
    11521 cgagcccaac gcgctgatcg gcttcgccgg cccgcgcgtg atcgagcaga cggtgcgcga
    11581 gaagctgcct gaaggcttcc agcgcgccga gttcctgctc gacaagggtg cgatcgacct
    11641 gatcgtcgac cgccgcgagc tgcgcgaccg cctcgcggtg ctgctcgcca tgctcaaccg
    11701 ccagcccgcg gacgtggtcg tcgggtgatg gccgagcaag ccggattgcc cgccagcctg
    11761 gacggctggc tcgccctgct ggaacagcgt catggccagc acatcgagct cgggctggag
    11821 cgcgtcgccg cagtgcgcgc gcgcatgcag gcggagtcgg acgcggtggt catcaccgtc
    11881 ggcggcacca acggcaaggg ttcgtgctgc gcgatgctcg agggcatcct gctcgcctcg
    11941 ggctaccgcg tgggctgcta cacctcgccc cacctgctgc gctacaacga gcgcgtgcgc
    12001 atcgacggca aggacgtcga cgacgcggcc ctggtggccg gcttcgcggc ggtcgagggc
    12061 gcgcgcggcg acaccgcgct gacctacttc gagcacggca ccctggcggc ctggcaggtc
    12121 ttcgccgcgg cccggccgga cgtgatcatc ctcgaggtcg gcctcggcgg ccggctcgac
    12181 gcggtcaacg tcttcgaacc cgactgcgcg ctggtcacca gcgtggccat ggaccacatg
    12241 gactacctcg gcgacacgcg cgaggccatc ggcttcgaga aggcgggcat cttccgcgcc
    12301 ggccgtcctg ccgtgtgcgg tgatccgcag ccgcccgcga gcctggtcga gcacgccgcg
    12361 gcgatcggcg cccagctgtg gatcagcggg cgcgacttcg gcttcggtgg cgaccgtcag
    12421 cagtggggct actggcgcta cgcccagccg ccgcgcgagg gtgcgctggt gcgccggggc
    12481 gggctcgcct acccggcgct gcgcggcgcc aaccagctgc tcaacgcggc ggcggtgatc
    12541 accgtgctcg agtgcctgcg cgaccgcatc ccggtgtcga tgcagcacgt tcgccagggc
    12601 ctcatgctgg tcgagctgcc cggccgtttc caggtgcagc cggggcgtcc ctcggtggtg
    12661 ctcgacgtcg cgcacaaccc gcaggccgcc ggcgtgctcg ccgacaacct cggcaacatg
    12721 ggcttctacc ccgagacctg ggcggtgctg ggcatgctcg ccgacaagga cgtggcgggc
    12781 gtggtcgagc tgatggccgg ccgggtcgac cactggctgc tcgccgacct gcccgggccg
    12841 cgcggcctct ccgccgaggc gctcgccgcg aaggtgcgcg cggtgaagga gggcgccgac
    12901 atccgctgct tccccacgcc ggccgaggcc tatgctgcgg cgcaaaaact ggtcgccgag
    12961 gatgatagaa tcgtcgtttt cggttccttc ctgacggtgt cggacgtgct cgccgcgatc
    13021 aaggcggcac ggcgcggatg aggttttgcg gtgactgagg cagattccct cgagatcaag
    13081 aagcgcgcgc gccgacgcct ggtcggtgcg atcgcgctcg ccctgctggc cgcgatcgtg
    13141 ctgccgatga tgatggacga ggagccgcat ccctcgatcg aggacatcca ggtctcgatt
    13201 cccgaccgcg acaaggcggt cgccgcgcgt cgcgccagtg cgcccgagag cgcgagcgcg
    13261 ccggtcgccg tcgccgtgcc ggaggacgac gaggtggtcg cggccgagaa gcccgcagcc
    13321 gagaaggccc cggccgcgcc ggacaagccc gcgccggcgg cggcagctgc gaagcccgcc
    13381 agcccgcctg ctccagccac accgcccgcc gcggcaacgc cgccgcgccc gcccgcgccc
    13441 gcggcgaccc ccgagccgcg ccgcccctcc gccgacgaag aggctcgcct gcgcgcgctc
    13501 atcgagggca aggcctcgcc cgcgcgcggc gacagctacg tgctgcagat cggcgccttc
    13561 agcgacgccg gcaaggctgc gaagctggtc gacgagctgc gcgcgcgcgg cttcccggcc
    13621 tacaccgagc gcgccggcaa cgtcacgcgg gtgcgtgtcg gcccggtcgc cgggcgcgcc
    13681 gaggccgacg ccgccgcagc ccgcctcaag tccgcgggtc atccggccgt gctgcaggcg
    13741 cgctgatttc cccagccatg accgtcttcg actacgtctt cctcggcctg ctcggctttt
    13801 ccgcgctcat cggcatgtgg cgcggcctgg tcagcgaggt catggcggtg ctcgcatggg
    13861 cggcagcgct cttcgccgca tggcgctata acggagaggc ggccgaggta ttcaccggca
    13921 tgatcgtcga gccgatgtgg cgacaggttg ccggtggcgc gctggtcgtg gtcggcgtgc
    13981 tcatcctcgc ggcgctgctg cgctacctgc tgcgcgagct gctgcgcgcc gccggcctgg
    14041 gcgccacgga ccgcttcttc ggtgcgctct tcggcatcgc gcgcgggctg gcggtcgcct
    14101 tcgtggtggt gctgatcggc gggctcgccg gagtcgcaaa ggagccgtgg tggcgcgatg
    14161 cgctgttctc ggcgccgctg gagtcggcgg tgatcgccgc caaaccctgg ctgcctgcag
    14221 aggtggccga caagattcga ttcagatagg cctcaatcca tgtgcggaat tctcggtgtc
    14281 gtcgccacct ccccggtcaa ccaactgctc tacgacggcc tccaggtgct gcagcaccgc
    14341 ggccaggacg cggcgggcat cgccacctcc gagggcgggc gcttccacat gcacaagggc
    14401 tccggcctgg tgcgcgatgt gttccgtacg cgcaacatgc gcaacctgga gggcaactgg
    14461 ggcatcggtc acgtgcgcta cccgaccgcg ggctcggcct acaacgccgc cgaggcgcag
    14521 cccttctacg tcaattcgcc cttcggcctg ctgctggcgc ataacggcaa cctgaccaac
    14581 tcggaagcgc tcaagcgcga gatgttcctg tccgacctgc gccacatcaa caccagcagc
    14641 gactccgagg tgctgctcaa cgtgttcgcg cacgagctgc aggccgcctg caagggcctc
    14701 aagatcgacg aggaggccat cttcaccgcg gtcgccgggg tgcatcggcg ctgccgcggc
    14761 gcctacgcgg tcgtggtgat gatcgccggc tacggcctgc tcgccttccg cgacccctac
    14821 ggcatccgcc cgctggtcat cggccgcaac gactgcgagg ccggcaccga gtggctggtg
    14881 gcctcggagt cggtggcggt cgatgtgctc ggcttccgcc tgctgcgcga cgtcgcgccg
    14941 ggcgaggcgg tgctggtcga taccgcgggg cgcttccaca gccgccagtg cgccgcgcgc
    15001 accgtgcacg cgccctgcat gttcgagttc gtctatctgg cgcggccgga ttcgatcatc
    15061 gacggcgtgt cggtgtacga gtcgcgcatg aagatgggcg agtacctcgc cgacaagatg
    15121 cgccgcacca tgcccaacgt gcacatcgac gtggtgatcc ccatccccga ctccagccgc
    15181 ccctcggcga tgcagatggc cgaccggctc gacctgccct tccgcgaggg cttcgtcaag
    15241 aaccgctaca tcggccgcac cttcatcatg ccgggccagg ccacgcggcg gaagtcggtg
    15301 cgccagaagc tcaacaccat ccaccaggag ttcaagggca agagcgtgct gctggtcgac
    15361 gactccatcg tgcgcggcac gaccagcaag gagatcgtca acatggcgcg cgaggcgggg
    15421 gccaccaggg tctatctcgc ctccgccgcg ccgccggtgc gctacgccaa cgtctacggc
    15481 atcgacatgc ccacccgcgg cgagctgatc gcctccgacc gcagcgaaga agagatctgc
    15541 cgcgagatcg gcgccgacgg cctcatctac caggacctcg acgacctcaa ggcctcggtg
    15601 cgcgcgctca acccctcgct gcagttcttc gagacctcct gtttcgacgg ccagtacgtc
    15661 accggcgaca tcaccgtcga gtacctcaac ggcgtcgaga accagcgcgg cgaggccaag
    15721 ccgggcaaga acgaccatga cgacgacggc gacggccaac tcgacctcaa cctcgcctcc
    15781 gacgccgagc gctgagcgct gaaccgctcc agacgaatcc agccacgatc acgatgaacc
    15841 gtccccttcc gcccgagctt caccccgaca ccctggccgt gcgcgccggc accgagcgca
    15901 cgcagttccg cgagcatggc gaggccatgt acctcacctc gagcttcgtc ttcggcagcg
    15961 ccgcgcaggc cgcggcgtgt ttctcgggcg aggaggaggg ctacgtgtac gcgcgcttct
    16021 ccaacccgac cgtgaccgcc atgcagaccc ggctcgccgc gctcgaaggc ggcgaggact
    16081 gcgtcgccac cgcctcgggc atgtcggcga tcctgtcgct ggcgatggcg accatgcagg
    16141 cgggcgacca cgtggtggcg tccaacggcc tcttcggcgc cacccagcag ctctttggcg
    16201 gcatcctgtc caagttcggc atcagcacga ccttcgtgcc ggccaccgac ctcgacgcct
    16261 ggcgcgccgc gattacgccg cgcaccaggc tgttcttcac cgagacgccg tccaacccgc
    16321 tcaccgaggt catcgacatc gccggcgtgg cggcgatcgc gcgcgccgcg ggggtgatct
    16381 tcgcggtcga caactgcttc tgcacaccgg cgctgcagcg cccgctcgag ctcggcgccg
    16441 acgtcgtcgt gcattcggcc accaagtatc tcgatggcca gggcagggtg ctcggcggcg
    16501 cggtggtcgg cagcaaggcg gtcaccgacg aggtcttcaa gttcctgcgc accgccggcc
    16561 cgaccctgtc gcccttcaac gcctgggtca tcctcaaggg cctggaaacc ctgcgcatcc
    16621 gcatggaggc gcagtcggcg agcgcactcg agctcgcgcg ctggctcgag gcccagcccg
    16681 gcgtggcgcg ggtgtactac ccggggctgg agtcccaccc gcagcacgcg ctggcgatgc
    16741 gccagcaaaa gagcggcggc gccatcgtca gcttcgacgt caagggcggc cgcgatgcgg
    16801 cgtggaaggt ggttgacgcc acccgcctga tctcgatcac cgccaacctc ggcgacacca
    16861 agagcaccat cacccacccc gccaccacca cccacggccg catcagcgcc gaggcgcgcg
    16921 ccaccgccgg catcggcgac ggcctgctgc gcatcgccgt ggggctggaa gacatcgacg
    16981 acctcaaggc cgatctcgcc cgcgggctgg cgagctgagc ccgcagcgtc gggaccgccc
    17041 cggcgctgcc gatgacgtcc aaccgtcggg atcgccccac cgcccgagat gcgcgatatc
    17101 cctctgtagg agcgccggca ggcgcgaaca ggacgccgaa agcctgcgcc tccgccgcca
    17161 cccacgcgtc ccggttcgcg cctgccggcg ctcctacaga aaccgccacg cgtcccggac
    17221 ctcctgcagg agctgcggca gctgcgaatg gagcggttcg gcgaccgcgg cgccggaagg
    17281 agcccggacg ccgctttcgc gcctgccggc gctcctacat ggagcgcagc gcctccgccg
    17341 ccacccacgc gtcccggttc gcgcctgccg gcgctcctac agaaaccgcc acgcgtcccg
    17401 gacctcctgc aggagctgcg gcagctgcga atggagcggt tcggcgaccg cggcgccgga
    17461 aggag
//
LOCUS       DAOTIN010000064        17455 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_3927_length_17455_cov_8.312069, whole genome shotgun sequence.
ACCESSION   DAOTIN010000064 DAOTIN010000000
VERSION     DAOTIN010000064.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 17455)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 17455)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17455
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3927_length_17455_cov_8.312069"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..522
                     /locus_tag="P5537_10590"
     CDS             <1..522
                     /locus_tag="P5537_10590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium chelatase domain-containing protein"
                     /protein_id="HRV78530.1"
                     /translation="SQHSQQVAGSCVLITQEGTRPLLVEVQALVDSSQSPNPRRLSVG
                     LEQNRLAMLLAVMHRHAGVVCFDQDVFVNAVGGVKITEPAADLAILFAIVSSLRDRPL
                     KRGLAVFGEVGLAGEIRPAPRGQERLKEAAKLGFDTAIVPRANAPKQPIEGLTVIAVE
                     RVEEALEQLRGLE"
     gene            658..918
                     /locus_tag="P5537_10595"
     CDS             658..918
                     /locus_tag="P5537_10595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HRV78531.1"
                     /translation="MLIMNMIGIGSRLRSARQARGLAQDELARLAGGGRTSLSQLENG
                     SIGEIGIRKVLRICALLGLELQVMPEGRLPTLDDLLAGRGRR"
     gene            915..1259
                     /locus_tag="P5537_10600"
     CDS             915..1259
                     /locus_tag="P5537_10600"
                     /inference="COORDINATES: protein motif:HMM:NF025041.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HipA N-terminal domain-containing protein"
                     /protein_id="HRV78532.1"
                     /translation="MMLEVWSDGVLSGRLDRVGSDPRRCAFAYDPSARPSEEVSLTMP
                     LKLAGDEYPDGLHPVLQMNLPEGRSSVLRPRAAFPAYSPRCWCGMRGGFGPIAQAMRR
                     VWEQGVTCSLVG"
     gene            complement(1272..1796)
                     /locus_tag="P5537_10605"
     CDS             complement(1272..1796)
                     /locus_tag="P5537_10605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation protease"
                     /protein_id="HRV78533.1"
                     /translation="MSTVAGEDGAPVQGHEAPAPGSGLEAVVPAPVLVFGWGNPSRGD
                     DALGPLFVDAVEAMRLPGVECLTDFQLQVEHALDLRGRARVLFVDASADAAAPFTFER
                     LEPARDASFTTHAVSPQAILQVYCEVEGELPPSCWLLAIRGEGWELGAPTSATARENL
                     RAAIAWSQTWLAQG"
     gene            complement(1793..3259)
                     /locus_tag="P5537_10610"
     CDS             complement(1793..3259)
                     /locus_tag="P5537_10610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe hydrogenase subunit alpha"
                     /protein_id="HRV78534.1"
                     /translation="MNFELETASVPGENLRRVAIDPVSRVEGHGKVTILLDEDNKVHQ
                     VRLHIVEFRGFERFIQGRPYWEVPVMVQRLCGICPVSHHLAASKALDLIAGASKVTPT
                     ADKMRRLMHYGQILQSHALHFFHLSSPDLLFGFGSEVGRRNIVGVAQQYPDIAKKGIL
                     LRKFGQEVIRLTAGKRVHGTGAVPGGVNRSLTADERKELLKDAYQMIAWSRDAVRIIK
                     ELHQQDPALYDHFGTVRSSFMGLVAPDGSLDLYHGVLRARDADGRILFDQVDYQTYDR
                     LITEEVKPWSYMKFPYFTAMGPEAGWYKVGPLARVQNCDSIPTPFAEHERRELVAYAG
                     GKPLHGSLAFHWARMIEMLFAAETIKDLLHDDDLSGTELMAGGERRREGVGVIEAPRG
                     TLFHHYQVGDDDLVTMANLIVSTTNNNQAMNTAVREVAKQYLDGQEITEGLLNHIEVA
                     IRAFDPCLSCATHALGKMPLEVTLVDAEGTELDRKYKA"
     gene            complement(3491..4066)
                     /locus_tag="P5537_10615"
     CDS             complement(3491..4066)
                     /locus_tag="P5537_10615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP oxidoreductase"
                     /protein_id="HRV78535.1"
                     /translation="MRIETTNGAGGAPRKLKVATVSLAGCFGCHMSFLDIDERLLPLL
                     ELVEFDRSPITDIKHCGPCDIGLIEGGVCNAENVHVLREFRANCKVLIALGACAVNGG
                     LPAQRNHLELADILQEVYRTGHGLAEGSRIPDDPELPLPLNQVHPVHEVVRIDYFLPG
                     CPPSGDAIWTFLTQLIEGKDPSLGHGLLHYD"
     gene            complement(4066..4797)
                     /locus_tag="P5537_10620"
     CDS             complement(4066..4797)
                     /locus_tag="P5537_10620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /protein_id="HRV78536.1"
                     /translation="MNDSFLLDGEDIPFTPGQTVMQAAAAAGKYIPHLCWHPDFAAHG
                     SCKLCTVKIGGRFATSCTVRAAAGQEVENRTEELDAKRRTLLQLLFVEGNHFCPSCEK
                     SGDCALQATAYEMGMLTPHFDHFYPDRPVDASHPDVLLDFNRCILCELCVRASRDVDG
                     KNVFALAGRGTRSHLVVNSDTGRLADTDFAATDRAAAVCPVGVILKKRVGFAVPIGLR
                     TYDRKPISAGMGADDKAGAGIGEAG"
     gene            complement(4794..6653)
                     /locus_tag="P5537_10625"
     CDS             complement(4794..6653)
                     /locus_tag="P5537_10625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="HRV78537.1"
                     /translation="MATAELEDILERHRRDPLQLLQILIELQARDGWLAPATLGALAD
                     ALGMPRARVESTASFYSFLHTRPAGEYRILFSDNITDRMLGNQALMQALCDKLWLQPG
                     KVSEDGLVSVATTSCTGMCDQGPALLANGRTVTRLTPERIDEMAHLIRRRVPVGDWPP
                     EWFHVEENIRRRDVLLDHGLAPGAALAAALERGPTGLLSEIERSALRGRGGAGFGSDI
                     KWRSCRDAWGDAHYVICNADEGEPGTFKDRVLLSSYFDLVVDGMCIAGMAIGANKGFI
                     YLRGEYRYLLDRLETRLAQRREQGLLGRNILGRGFTFDIEIHLGAGAYICGEESALIE
                     SLEGKPGKPRIRPPFPVTNGYRGQPTTVNNVETLALAALIAVRGGEWFRAIGTPASTG
                     TKLLSVSGDVARPGIYEFPFGVSVTGVLEAAGARDTQAVTSAGAAGHCLAADEFGRRI
                     AFEDVATGGSIMVFDASRDMFEVARNFAHFFAHESCGFCTPCRVGTAVNARLLDKLAA
                     DHGSPYDLDEIAKMHRLMQGASHCGLGNTATIAIDDMLAKFRPAFERRLHSPDYEPAF
                     DLDAALSQARRMTGRDDAGAHLGDNHEALAEARPHAQGAHSSADPVSAKDLQP"
     gene            complement(6768..9242)
                     /locus_tag="P5537_10630"
     CDS             complement(6768..9242)
                     /locus_tag="P5537_10630"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HRV78538.1"
                     /translation="MDLAQFTLQYDRPSDDVDSLKRAIANKLMYQIGKNPDSALPEDW
                     LHAVAYTVRDHLVERWMKTTRASYAQDVKRVYYLSMEFLIGRSLGNAMLALELAGPVR
                     EALRALDIDPDSLPELEPDAALGNGGLGRLAACFLDSMATLGVPGFGYGIRYDYGMFR
                     QQIVDGQQVEVPDYWLTHGNPWEFPRPEIRMRIRFGGHLQEDGGRVHWVGTDDVLAMA
                     YDSIIPGYGTEVTNTLRLWSARATEEIDLSAFNRGNYFGAVESKNHSENVSRVLYPDD
                     STLEGRELRLRQEYFFVSASLQDIVRRYRVGHSDFDALPDKVSIHLNDTHPVLAVPEL
                     MRLLVDEHGLAWAHAWALCRRVFSYTNHTLMHEALETWPLEMLGRVLPRHLRIIFDIN
                     AHFLAELNAELGPDVERMRRMSLIDEQGERRVRMAYLAIVASHSVNGVSALHSALMRE
                     SIFVDFARVWPQRFNNKTNGVTPRRWLAHANPGLAALIDSRIGPGWRRDLEELHGLRA
                     HADDADFLHTLRAVKQANKLRLAQWIGRHCGLHVDPAALFDVHVKRIHEYKRQLLNVL
                     HLVSRYQRILAEPDAEHVPRVAIFSGKAASAYRMAKLVIRLINDVAAVINADPRVGDR
                     LKVVFVPNFSVSLAELIIPAADLSEQISTAGTEASGTGNMKLALNGALTIGTLDGANV
                     EIREQVGEDNLFIFGHTAAEVAQIRNGGYQPRQHYERDPRLAAALDAIREGLFSPDEP
                     VRYQAIFDTLVNWGDHYLLLADYASYLDAQAEADARYRDPLQWSRCSLLNIAGMGVFS
                     SDRTIAEYARTIWHTAPLRIGSPGGL"
     gene            complement(9718..11178)
                     /gene="glgA"
                     /locus_tag="P5537_10635"
     CDS             complement(9718..11178)
                     /gene="glgA"
                     /locus_tag="P5537_10635"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - glycogen (starch) synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HRV78539.1"
                     /translation="MRILQVCAEIFPLLKTGGLADVAGALPPALGALGADVRVLLPGF
                     DAILAGLESPVEVARLQAPGEMGSHPARLLRGRLPAAGVDAYVIDAPGWYRRAGGPYA
                     DAGQQSYADNHLRFGLLGWTAAGLAQGLDASWQPEVVHAHDWHAGLVPAWLQAAATRG
                     RPLPGCVFTVHNLAYQGMFPRACFDALGLPAHFFSIHGVEFHGQLNFMKAGLYYAERV
                     TTVSPSYAREIQGPEQGCGLDGLLRARAHELSGILNGVDAAVWDPATDALLPARYMAD
                     DMAGKARCRSALRRELGLAVKADGPLYCVVSRLTEQKGLHLVLHALPALLAGGGQFAL
                     LGSGDAGLEAAFRDAAAATPDAVAVRLGYDEAFAHRLIAGSDVILVPSHYEPCGLTQL
                     YGLKYGTLPLVRRVGGLADTVADTRLETLDTDATGFVFEEFSAAALERTLQRVHALHR
                     RPAEWRRVRARGMAQDFGWARAAADYLALYRGLMPM"
     gene            complement(11195..12463)
                     /gene="glgC"
                     /locus_tag="P5537_10640"
     CDS             complement(11195..12463)
                     /gene="glgC"
                     /locus_tag="P5537_10640"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HRV78540.1"
                     /translation="MPAEAANRRRILTRSTLALVLAGGRGSRLRDLTNVRAKPAVHFG
                     GKFRIIDFALSNCMNSGLRRIGVITQYKSHSLLRHLQRGWSFLRNEMGEFVDLLPAQQ
                     RTDEEHWYQGTADAVFQNLDIIRNSTPPDYIVVLAGDHVYKMDYSIMLEDHVASGRGV
                     TVGCIEVPREEARAFGVMAIDERRHITAFVEKPADPPPMPGNPELSLASMGIYVFSAD
                     YLYHLLEDDARNPDSSHDFGKDLIPRAVAEHQALAHPFTLSAIATPPFSGPYWRDVGT
                     VDAYWAANLDLASTTPALNMYDKDWPIWTYQEQLPPAKFVHDLDGRRGEAINALVSGG
                     CIVSGSTVRESVLFSNVLVRSYSTIEEAVVLPDVQINRHCRLKKVVIDRRCVIPEGTV
                     IGEDAEGDARRFHRTEGGVVLVTREMLDRL"
     gene            complement(12466..>12677)
                     /locus_tag="P5537_10645"
     CDS             complement(12466..>12677)
                     /locus_tag="P5537_10645"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78541.1"
                     /translation="SVLLLINPAADACRFRLPAGQWTPAFDSTRADGSPAAHAPGHEA
                     NPVEHTLPARAVLVLLQSAEQHQES"
     assembly_gap    12678..12777
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<12778..14816)
                     /gene="glgX"
                     /locus_tag="P5537_10650"
     CDS             complement(<12778..14816)
                     /gene="glgX"
                     /locus_tag="P5537_10650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004133 - glycogen debranching enzyme
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen debranching protein GlgX"
                     /protein_id="HRV78542.1"
                     /translation="MDRIPPAGAEGTPVLRPGQPWPLGASLAEDAVEAGVNFAVWAPD
                     AEAIELCLFDAEGREELCRLALPSCSEGVWHGFLPAARAGLVYGLRAHGPWAPRRGHW
                     FNPAKLLLDPWAQEVVGSYGRQGPGPADDAELAAQLDAFRATRSDDPRLPDARDNAAF
                     APKARVPVPIVRAPIPMETAGRPPRPRIPRDRTVLYEAHVRALTMRHPGLPPALRGSY
                     GALAHPVMLEHYRALGITTLSLLPLHFRADEAALQRRGLANHWGYAPAAWLAPEPRYG
                     SGRAGTTPADELAEAIDALHAAGFEVVLDVVFNHTAELDADGPLLSLRGLANARAYHL
                     DPQDPARYRDWSGCGNAVNLGEPRMVELVVGALRHWATRYRVDGFRLDLAVTTGRDRR
                     GHFDAGAALFAAIGADPLLARLKWIAEPWDLGPDGYRLGGFAPGWMEWNDRFRDTMRA
                     WWLCGGGDRGAFAHRFAGSAAEFDHDRRAPTASINFLCAHDGFGLRDLVSHDHRHNAA
                     NGEHNRDGHAHNHSWNCGVEGPTDDPVVLALRARLQRALLASLLLAQGTPMLLAGDEL
                     GHSQGGNNNAYCQDNETTWLDWAGADRALLACVQRLLALRAAHPALRQANWLRGPEHG
                     EAASVRWLRPDGAELQAADWNDPRERALAILLHPPGQASSTAGLGGVSLPATSSP"
     gene            complement(14950..17142)
                     /gene="glgB"
                     /locus_tag="P5537_10655"
     CDS             complement(14950..17142)
                     /gene="glgB"
                     /locus_tag="P5537_10655"
                     /EC_number="2.4.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003844 - 1,4-alpha-glucan branching
                     enzyme activity [Evidence IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HRV78543.1"
                     /translation="MNPDLARVAPESLQSLLQASHPDPFALLGAHAVAGGVVLRALLP
                     GARQVVALDHDGKMLLELQPQDGSPLFVGALPARALPLRYHLHVHWDDGGETHFDDAY
                     RFGALIEDLDVWLLAEGSHHRPYEWLGAHPVTVDGVAGTRFAVWAPNARRVSVVGGFN
                     AWDGRRHMMRHRRECGVWEIFVPGIGEGELYKYEVLGADGVVRLKADPFAFRAELRPH
                     TASVVQRLLPGLAIDESRRRVNALDAPISIYEVHLGSWQRKEDGGWLSYRELAERLVP
                     YAVELGFTHLELMPVHEHPFDGSWGYQPTGLYAPSARFGTPEDFRAFTDAARAAGLGV
                     ILDWVPAHFPSDAHGLAEFDGTHLYEHADPREGFHQDWNTLIYNYGRAEVRNYLASNA
                     LYWIERFGADGLRVDAVASMLYRDYSRKAGEWVPNRFGGRENLEAIDFLRRMNHLVGT
                     QRPEAITLAEESTAFPGVSRPPSPDLQGGGLGFHYKWNMGWMNDLLAYLARDPVHRRH
                     HHDQLRFSLVYAFSENFVLPLSHDEVVHGKGSLLAKMPGDDWQKFANLRLLYGYMWAH
                     PGKKLLFMGCEFAPWAEWNADASLPWTLLGQPAHAGMQRLVRDLNRVLRSHPALYELD
                     TASAGFRWISHDDAAHSVLVFERRARDGRGVVVACNFTPVAREGWRIGVPAAGTWREL
                     INTDDAVYGGSGVTNGTLPAESVPWQGEAQSMVLRLPPLGVAMFVHED"
BASE COUNT         2512 a         5816 c         6410 g         2617 t
ORIGIN      
        1 tcgcagcact cgcagcaggt cgccggcagc tgcgtgctga tcacccagga gggcacgcgc
       61 ccgctgctgg tcgaggtgca ggccctggtc gattcgtcgc agagccccaa cccccggcgc
      121 ctgtcggtgg gcctggagca gaaccgcctc gcgatgctgc tcgcggtcat gcaccgccac
      181 gccggcgtgg tgtgcttcga ccaggacgtg ttcgtgaacg cggtcggcgg ggtcaagatc
      241 accgagccgg cggccgacct cgcgatcctg ttcgcgatcg tgtcctcgct gcgcgatcga
      301 ccgttgaagc gcggcctggc ggtgttcggc gaagtcggcc tcgccggcga gatccggccc
      361 gcaccgcgcg ggcaggaacg gctgaaggaa gccgccaagc tcggcttcga caccgccatc
      421 gttccgcgcg cgaacgcgcc gaagcagccg atcgaggggc tcaccgtgat cgcggtggag
      481 cgggtggagg aggcgctcga gcagttgcgc gggctggaat aggcgcaggg aacccgcgag
      541 cgggatccgc cttcccggtg ccaagtcggt gcatcggaaa acgcacgttc ggggcgtagg
      601 catcgtgcat gttcagtatg ctgaacatgg agccagaata acgacgtctt gtttcgtatg
      661 ctgatcatga acatgatcgg aatcggctcg aggcttcgct cggcgcgcca ggcacgcggg
      721 ctcgcccagg acgaactcgc acgcctcgcg ggtggtggcc gtaccagtct gtcgcagctc
      781 gagaacggca gcatcggcga gatcgggatc cgcaaggtcc tgcgcatctg cgcgttgctg
      841 gggctggagt tgcaggtgat gcccgagggg cggctgccga cgctggatga tctgctggcg
      901 ggacgcggga gacgatgatg ctggaggtgt ggtcggatgg cgtgctgagc ggacggctcg
      961 atcgagtggg atcggatccg cgacgctgtg ccttcgccta cgacccttct gcgcggccga
     1021 gcgaagaggt ctcgctgacc atgccgctga agctcgccgg cgatgaatat ccggacggac
     1081 tccatccggt gttgcagatg aacctgccgg aggggcgatc gagcgttttg cgacctcgag
     1141 cggcgtttcc ggcgtacagc ccaaggtgct ggtgcgggat gcgcggcggc ttcggcccga
     1201 ttgcgcaggc gatgcggcgg gtgtgggagc agggcgtcac gtgcagcctg gtcggatgag
     1261 tccggcgcgg ctcagccctg tgcaagccag gtttgcgacc aggcgatcgc cgcgcgcagg
     1321 ttctctcgcg cggtggcgct cgtcggggca ccaagctccc agccttctcc gcgaatcgcc
     1381 agcagccagc acgacggcgg aagctcgcct tcgacctcgc aatacacctg caggatggcc
     1441 tgcggcgaca ccgcgtgggt cgtgaagctc gcgtcgcgcg cgggctcgag gcgctcgaac
     1501 gtgaagggcg ctgccgcatc ggccgacgca tccacgaaca gcacccgcgc gcgcccgcgc
     1561 agatccagcg cgtgctcgac ctggagctgg aagtcggtga ggcattcgac gccgggcagc
     1621 ctcatcgcct cgaccgcgtc gacgaacagc ggcccgagcg catcgtcccc ccggctcggg
     1681 ttgccccagc cgaacaccag cactggcgcg ggtaccaccg cctccagccc ggagcccggc
     1741 gcgggcgctt cgtgcccctg caccggcgca ccgtcctccc cggccacggt gctcatgcct
     1801 tgtatttccg gtccagctcc gtgccctcgg catccaccag tgtgacctcc agcggcatct
     1861 tgccgagcgc gtgggtggcg caggacaggc aggggtcgaa ggcgcggatg gcgacctcga
     1921 tgtggttaag caggccctcg gtgatctcct gcccgtcgag gtattgcttc gccacctcgc
     1981 gcacggcggt gttcatcgcc tggttgttgt tggtggtgga gacgatcagg ttggccatgg
     2041 tgacgaggtc gtcgtcgccc acctggtagt ggtggaagag ggtgccgcgc ggggcctcga
     2101 tcacgcccac gccctcgcgc cgacgctcgc cgccggccat cagctcggtg ccggagaggt
     2161 cgtcgtcgtg cagcaggtcc ttgatggtct cggcggcgaa gagcatctcg atcatgcgtg
     2221 cccagtggaa ggccaggctg ccatgcagcg gcttgccacc ggcgtaggcg acgagctcgc
     2281 ggcgctcgtg ctcggcaaac ggcgtgggga tgctgtcgca gttctgcacg cgcgcgagcg
     2341 ggccgacctt gtaccagccg gcctcggggc ccatggccgt gaagtagggg aacttcatgt
     2401 agctccaggg cttgacctcc tcggtgatga ggcggtcgta ggtctgatag tccacctggt
     2461 cgaacaggat ccggccatcg gcgtcgcggg cgcgcagcac gccgtggtag aggtcgaggc
     2521 tgccatccgg cgcgaccagg cccatgaagc tcgagcgcac ggtgccgaag tggtcgtaga
     2581 gcgccgggtc ctgctggtgg agctccttga tgatgcgcac cgcgtcgcgg ctccaggcga
     2641 tcatctggta ggcgtccttg agcagctcct tgcgctcgtc ggcagtcagc gaacgattga
     2701 ccccgcccgg caccgcgccg gtgccatgca cgcgcttgcc ggcggtgagg cggatcacct
     2761 cctggccgaa cttgcgcagc agaatgccct tcttcgcgat gtcggggtat tgctgcgcca
     2821 cgccgacgat gttgcgccgg ccgacctcgg agccgaagcc gaacagcagg tcgggcgagg
     2881 acaggtggaa gaagtgcagc gcgtgcgact gcaggatctg gccgtagtgc atcaggcggc
     2941 gcatcttgtc ggccgtcggg gtgaccttgc tggcgccggc gatgaggtcg agcgccttgc
     3001 tcgccgcgag gtggtgcgag accgggcaga tgccgcacag gcgctgcacc atcaccggca
     3061 cctcccagta cggccgcccc tggatgaagc gctcgaagcc acggaactcg acgatgtgca
     3121 ggcgcacctg atgcaccttg ttgtcctcgt cgagcaggat cgtgaccttg ccgtggcctt
     3181 ccacgcgcga gacagggtcg atggcgacgc ggcgcaggtt ttcgccggga accgaggcgg
     3241 tttcgagttc gaagttcatg gctggtttcc ttcgcgtcct tgagtaagcg ttctgcgggg
     3301 gccgcagcgc ctatgcggtg aagaccacgc tacgagggtg tctgtaggag cgccggcagg
     3361 cgcgaaaacg gcaatcgggg acggcacgcg cgtcgcacct ccggtcgtcc gcttcgcggc
     3421 tgccgccgcc cctacgtcgg gccacgccgc gagggtgtct gtaggagcgc cggcaggcgc
     3481 gaaagcggcc tcagtcgtaa tgcagcagcc catgtccgag actggggtcc ttgccctcga
     3541 tcagctgggt caggaaggtc cagatcgcat cgcccgaggg tgggcagccc ggcaagaagt
     3601 agtcgatcct caccacctca tgcaccggat ggacctggtt cagcggcagc ggcagctcgg
     3661 ggtcgtcggg gatgcggctg ccttccgcga ggccgtggcc ggtgcggtag acctcctgca
     3721 ggatgtcggc gagctcgagg tggttgcgct gcgccggcag gccgccgttg accgcgcacg
     3781 cgccgagcgc gatcagcacc ttgcagttgg cgcggaactc gcgcagcacg tgcacgttct
     3841 cggcgttgca caccccgccc tcgatgagcc cgatgtcgca ggggccgcag tgcttgatgt
     3901 cggtgatcgg cgagcggtcg aactcgacga gctcgagcag cggcagcagg cgctcgtcga
     3961 tgtcgaggaa ggacatgtgg cagccgaagc agcccgccag cgacacggtc gccaccttga
     4021 gcttgcgtgg cgcgcctccc gcgccgttcg tggtctcgat acgcatcagc cggcctcccc
     4081 gatgcccgcg ccggccttgt cgtcggcgcc catacccgcg ctgatcggct tgcggtcgta
     4141 ggtgcgcagc ccgatcggca ccgcgaagcc cacccgtttt ttaaggatca cccccaccgg
     4201 gcacaccgcg gcggcgcggt cggtggcggc gaagtcggtg tcggcgaggc gccccgtgtc
     4261 gctgttgacc accaggtgcg accgggtgcc gcgcccggcg agcgcgaaca cgttcttgcc
     4321 atcgacatcg cggctggcgc gcacgcacag ctcgcacagg atgcagcggt tgaagtcgag
     4381 cagcacgtcg gggtgcgaag cgtcgaccgg acggtcgggg tagaagtggt cgaagtgcgg
     4441 cgtcagcatc cccatctcgt aggccgtggc ctgcagcgcg cagtcgccgc tcttctcaca
     4501 cgacgggcag aagtggttgc cctcgacgaa gagcagctgc agcagcgtgc ggcgcttggc
     4561 gtcgagctct tcagtgcggt tctccacctc ctggccggcg gcggcgcgca ccgtacagga
     4621 ggtggcgaag cggccgccga tcttgaccgt gcacagcttg cacgagccgt gcgcggcgaa
     4681 gtccggatgc cagcacaggt gcggaatgta cttgcccgcg gcggccgcgg cctgcatcac
     4741 ggtctggccg ggcgtgaagg ggatgtcctc gccgtcgagc aggaaggagt cgttcatggc
     4801 tgcagatcct ttgccgagac cgggtcggcg gaggagtggg cgccctgcgc atggggccgc
     4861 gcctcggcca gcgcctcgtg gttgtcgccg aggtgggcgc cagcgtcgtc gcggcccgtc
     4921 atccggcgcg cctgtgacag cgcggcgtcg aggtcgaagg cgggctcgta gtcgggcgag
     4981 tgcaggcggc gctcgaaggc ggggcggaac ttggccagca tgtcgtcgat cgcgatcgtc
     5041 gccgtgttgc ccaggccgca gtggctggcg ccctgcatca ggcggtgcat cttcgcgatc
     5101 tcgtcgaggt cgtagggcga gccgtggtcg gcggcgagct tgtccagcag gcgcgcgttg
     5161 accgcggtgc cgacgcggca gggcgtgcag aagccgcagc tctcgtgcgc gaagaagtgg
     5221 gcgaagttgc gcgccacctc gaacatgtcg cgcgaggcgt cgaagaccat gatcgagccg
     5281 ccggtggcga cgtcctcgaa ggcgatgcgg cggccgaact cgtccgccgc caggcaatgc
     5341 ccggccgcgc cggcgctggt caccgcctgc gtgtcgcgcg cgccggcggc ctcgagcacc
     5401 ccggtgacgc tgacgccgaa gggaaactcg tagatgcccg ggcgcgccac gtcgcccgac
     5461 accgacagca gcttggtgcc ggtcgaggcc ggggtgccga tggcgcggaa ccactcgcca
     5521 ccgcgcaccg cgatcaacgc cgcgagcgcg agcgtctcga cgttgttcac cgtggtcggc
     5581 tggccgcggt agccgttggt gaccgggaag ggcgggcgga tgcgcggctt gcccggcttg
     5641 ccctcgagcg actcgatgag cgcggactcc tcgccacaga tgtaggcccc ggcgccgagg
     5701 tggatctcga tgtcgaaggt gaagccgcgg ccgaggatgt tgcgcccgag caggccttgt
     5761 tcgcggcgct gggcgagccg cgtctcgagg cggtcgagca ggtagcggta ttcgccgcgc
     5821 agatagatga agcccttgtt ggcgccgatc gccatgccgg caatgcacat gccgtcgacc
     5881 accaggtcga agtaactcga cagcagcacg cggtccttga aggtgccggg ctcgccctcg
     5941 tcggcgttgc agatgacgta gtgcgcgtcg ccccaggcgt cacggcacga gcgccacttg
     6001 atgtcgctgc cgaagcccgc gccgccgcgg ccgcgcagcg cggagcgttc gatctccgac
     6061 agcaagccgg tggggccgcg ctccagggcc gcagcgagcg ccgcgccggg cgccaggccg
     6121 tggtcgagca gcacgtcgcg gcggcggatg ttctcctcga cgtggaacca ctccggcggc
     6181 cagtctccca ccggcacgcg acggcggatc aggtgcgcca tctcgtcgat gcgctccggg
     6241 gtgaggcggg tgaccgtgcg cccgttggcc agcagcgccg gcccctggtc gcacatgccg
     6301 gtgcaagacg tggtcgccac gctcaccagg ccgtcctccg acaccttgcc cggctgcagc
     6361 cacagcttgt cgcacagcgc ctgcatcagc gcctggttgc ccagcatgcg gtcggtgatg
     6421 ttgtccgaga acaggatgcg gtactcgccc gccggccggg tgtgcaggaa gctgtagaag
     6481 ctcgccgtgc tctcgacacg ggcgcgcggc atgccgagcg cgtcggccaa cgcgccgagg
     6541 gtggccggcg caagccagcc gtcccgggcc tggagctcga tcaggatctg cagcaactgc
     6601 agcggatcgc gccggtgccg ttcgaggatg tcttcgagtt ctgctgtcgc cacgatgggc
     6661 tccctgtctt tgcgtgcact gcagcacgat tatcgcgcgg acccggcggg gcgcgtcatg
     6721 gaaatggtgc ggccccgtga tccaatgcgc ttatccccgc cttcccctca cagcccgccc
     6781 gggctgccga tgcgcagcgg cgcggtgtgc cagatcgtgc gtgcgtattc ggcgatggtg
     6841 cggtcggacg agaacacccc catgccggcg atgttgagca ggctgcaccg gctccattgc
     6901 agcggatcgc gatagcgcgc gtcagcctcg gcctgggcgt cgagatagct ggcatagtcg
     6961 gccagcagca ggtagtggtc gccccaattc accagggtgt cgaagatcgc ctggtagcgc
     7021 acgggctcgt ccgggctgaa gaggccctcg cggatcgcgt cgagcgccgc ggccagccgg
     7081 gggtcgcgct cgtagtgctg gcgcggctgg tagccgccgt tgcggatctg cgcgacctcg
     7141 gccgcggtgt ggccgaagat gaacaggttg tcctcgccga cctgctcgcg gatctcgacg
     7201 ttggcgccgt ccagcgtgcc gatggtgagt gcgccgttga gcgcgagctt catgttgccc
     7261 gtgcccgagg cctcggtgcc ggcggtggag atctgctcgg agaggtcggc cgcggggatg
     7321 atcagctccg ccaggctcac cgagaagttg ggcacgaaga ccaccttgag gcggtcgccg
     7381 acgcgcggat cggcgttgat gaccgcggcc acgtcgttga tgaggcggat caccagcttg
     7441 gccatgcggt aggccgaggc cgccttgccc gagaagatcg ccacccgcgg cacgtgctcg
     7501 gcgtccggct cggcgaggat gcgctgatag cggctcacca ggtgcagcac gttgagcagc
     7561 tggcgcttgt actcgtggat gcgcttgaca tgcacgtcga agagcgccgc gggatcgacg
     7621 tggagtccgc aatgccggcc gatccactgc gccaggcgca gcttgttggc ctgcttcacc
     7681 gcgcgcagcg tgtgcaggaa gtcggcgtcg tcggcgtgcg cacgcaggcc gtggagctcc
     7741 tcgaggtcgc gccgccatcc cgggccgatg cggctgtcga tcagcgccgc cagccccggg
     7801 ttggcgtgcg ccagccagcg ccgcggggtg acgccgttgg tcttgttgtt gaagcgctgc
     7861 ggccacacgc gcgcgaagtc gacgaagatc gactcgcgca tcagcgccga atggagcgcc
     7921 gacacgccat tgaccgaatg cgaggcgacg atcgccaggt aggccattcg cacgcggcgc
     7981 tcgccctgtt cgtcgatcag cgacatgcgg cgcatgcgct cgacgtcggg cccgagctcg
     8041 gcgttgagct cggcgaggaa gtgcgcgttg atgtcgaaga tgatgcgcag atggcgcggc
     8101 agcacgcgcc cgagcatctc cagcggccag gtctccagcg cctcgtgcat cagggtgtgg
     8161 ttggtgtagg agaacacccg ccggcacagc gcccaggcgt gtgcccacgc cagcccgtgc
     8221 tcgtcgacca gcaggcgcat cagctcgggc accgcgagca ccgggtgggt gtcgttgagg
     8281 tggatgctga ccttgtcggg cagggcgtcg aagtcgctgt gaccgacgcg gtagcggcgc
     8341 acgatgtcct gcaggctcgc ggagacgaag aaatactcct ggcgcaggcg cagctcgcgg
     8401 ccttccaggg tggaatcgtc gggatagagc acgcgcgaca cgttctcgga gtggttcttg
     8461 ctttccaccg cgccgaagta gttgccgcgg ttgaaggccg agaggtcgat ctcctcggtc
     8521 gcgcgcgccg accacaggcg cagcgtgttg gtcacctcgg tgccgtagcc ggggatgatc
     8581 gagtcgtagg ccatggccag cacgtcgtcg gtgcccaccc agtgcacccg cccgccgtcc
     8641 tcctgcaggt ggccgccgaa gcggatgcgc atgcggatct cggggcgggg gaactcccac
     8701 gggttgccgt gggtgagcca gtagtcgggc acctcgacct gctgcccgtc gacgatctgc
     8761 tggcggaaca tgccgtagtc gtagcggatg ccgtagccga agccgggaac gccgagcgtc
     8821 gccatcgagt cgaggaagca ggccgccagg cggccgaggc cgccgttgcc gagcgcggcg
     8881 tcgggctcga gctcgggcag gctatcgggg tcgatgtcga gcgcgcgcag cgcctcgcgc
     8941 accgggccgg cgagctcgag cgcgagcatg gcgttgccca ggctgcggcc gatgagaaac
     9001 tccatcgaca ggtaatagac gcgcttgacg tcctgcgcat agctcgcgcg ggtggtcttc
     9061 atccagcgct cgaccaggtg gtcgcgcacg gtgtaggcga ccgcatgcag ccagtcctcc
     9121 gggagggcgg aatccgggtt cttgccaatc tggtacatca gtttgttggc gatcgcgcgc
     9181 ttgagggagt ctacgtcgtc gctcgggcgg tcgtactgca gggtgaactg ggcaagatcc
     9241 atgagaattc gctggcgttc cgggaaacgg gtggcgcccg cgcgcggcac atgacgcgcg
     9301 gaggcgaaac ccggtatttt aggcctttcg caagggaagg cgcgacgaag cagaccgcaa
     9361 ggtggcgctg cgcgtcggcg aggcctcctt cgcgcctgcc ggcgctccta caggaagcgg
     9421 tgcgggctcg atgttcgtgc cacccaccga gccgggatgg gctcgtgtag gagcggcggc
     9481 agccgcgaat cgggccttcg cacatgcgaa tcgcgtcggt gcagcctcct tcgcgcctgc
     9541 cggcgctcct acaggaggcg gcgaggactc gatggtctcc tccaggagcg gcgagggttc
     9601 ggtgctcgcc cccccttcga gcgatgatgg tttcctgtag gagcgccggc aggcgcgaat
     9661 gctgcgcttg ggcggcgttg tgcgtcggcg agcgctcctg cgggcctgcc ggcgctccta
     9721 cattggcatg aggccgcggt agagggcgag gtagtcggcg gcggcgcggg cccagccgaa
     9781 gtcctgcgcc atgccgcggg cgcgcacgcg tcgccattcg gccgggcggc ggtggagggc
     9841 gtgcacgcgc tgcagcgtgc gctcaagcgc agcggcggag aactcctcga agacgaagcc
     9901 ggtggcgtcg gtgtccagcg tctcgagtcg tgtgtcggcc accgtgtcgg ccaggccacc
     9961 gacacgccgc accaagggaa gggtgccgta cttgaggccg tagagctggg tcagcccgca
    10021 gggctcgtag tgcgagggca ccaggatcac gtcgctgccg gcgatcaggc ggtgggcgaa
    10081 ggcctcgtcg tagccgagac gcaccgccac cgcatccggc gtcgccgcgg ccgcgtcgcg
    10141 gaaggcggcc tccagaccgg cgtcgccgct gccgagcagg gcgaactggc cgccgcccgc
    10201 cagcagcgcg ggcagcgcgt gcagcaccag gtgcaggccc ttctgctcgg tgagccggct
    10261 caccacgcag tacagcgggc cgtctgcctt gaccgccagc ccgagctcgc gcctcagcgc
    10321 gctgcggcag cgcgccttgc ctgccatgtc gtccgccatg tagcgcgccg gcagcagcgc
    10381 gtccgtggcc ggatcccaca ccgccgcatc gacgccgttg aggatgcccg agagctcatg
    10441 cgcgcgggcg cgcaagagtc cgtccagccc gcagccctgt tccggcccct ggatctcgcg
    10501 cgcatagctc gggctcaccg tggtgacacg ctcggcgtag tacagccccg ccttcatgaa
    10561 gttgagctgg ccgtgaaact ccaccccatg gatcgagaag aaatgcgccg gcagcccgag
    10621 cgcatcgaag caggcgcgcg gaaacatgcc ctggtaggcg aggttgtgca ccgtgaacac
    10681 gcaacccggc aacggccgcc ccctcgtcgc cgcggcctgc agccaggcgg ggacgaggcc
    10741 ggcgtgccag tcgtgcgcgt gcaccacctc gggctgccag gacgcgtcca gcccctgcgc
    10801 gagcccggcc gcggtccagc cgagcaggcc gaagcgcagg tggttgtcgg cgtaggactg
    10861 ctgcccggcg tcggcgtagg ggccgcccgc gcgccgatac cagcccgggg cgtcgatcac
    10921 gtaggcgtcg acgccggccg cgggcaggcg cccccgcagc aggcgcgcgg ggtggctccc
    10981 catctcgccc ggcgcttgca ggcgggcgac ttcgacgggc gactccagcc cggcgaggat
    11041 ggcgtcgaag ccgggcagca atacccgtac gtcggccccg agcgcgccca gggccggtgg
    11101 cagcgccccc gcgacgtcgg ccagcccgcc ggtcttcagc aacgggaaga tctcggcaca
    11161 aacctgaagg atccgcatcg tctcgtcccc cggctcagag tcggtcgagc atttcgcgcg
    11221 tcaccagcac cacgccaccc tcggtgcggt ggaagcggcg cgcatcgccc tcggcgtcct
    11281 cgccgatcac ggtgccctcg gggatcacgc agcggcgatc gatgaccacc ttcttgaggc
    11341 ggcaatggcg gttgatctgc acatcgggca gcaccaccgc ctcctcgatc gtgctgtagg
    11401 agcgcacgag cacgttggag aacagcaccg actcgcgcac cgtcgagccc gaaacgatgc
    11461 agccgcccga caccagcgcg ttgatcgcct cgccgcggcg gccgtcgagg tcgtggacga
    11521 acttggccgg cggcagctgc tcctggtagg tccagatcgg ccagtccttg tcgtacatgt
    11581 tgagcgccgg cgtggtcgaa gcgaggtcga ggttggccgc ccagtaggca tcgaccgtac
    11641 cgacgtcgcg ccagtagggg ccggagaagg gcggggtggc gattgccgac agcgtgaacg
    11701 ggtgggcgag cgcctggtgc tcggccaccg cgcgcgggat caggtccttg ccgaagtcgt
    11761 ggctggagtc cggattcctc gcgtcgtcct cgagcaggtg gtagaggtag tcggccgaga
    11821 acacgtagat gcccatgctg gcgagcgaca gctccgggtt gcccggcatc ggcggcgggt
    11881 cggcgggctt ctcgacgaag gcggtgatgt ggcgccgctc gtcgatcgcc atcacgccga
    11941 aggccctggc ctcctcgcgc ggcacctcga tgcagccgac ggtgacgcca cggccactcg
    12001 cgacatggtc ctcgagcatg atcgagtaat ccatcttgta cacatggtcg ccggcgagca
    12061 cgacgatgta gtcgggcggg gtggagttgc ggatgatgtc caggttctgg aagaccgcgt
    12121 cggcggtgcc ctggtaccag tgttcctcgt cggtgcgctg ctgcgccggc agcaggtcga
    12181 cgaactcgcc catctcgttg cgcaggaagc tccagccgcg ctgcaggtgg cgcagcagcg
    12241 agtgcgactt gtactgggtg atcaccccga tgcggcgcag gcccgagttc atgcagttcg
    12301 acagcgcgaa gtcgatgatg cggaacttgc cgccgaagtg caccgccggc ttggcgcgca
    12361 cgttggtgag atcgcgcagg cgcgagccgc gcccgccggc gagcacgagg gcgagggtgc
    12421 tgcgcgtgag gatccgtcgt cggttggcag cttcggcagg catgatcagg actcctggtg
    12481 ttgttctgcg gattggagca ggacgagcac ggcgcgcgcg ggcagcgtgt gctcgacggg
    12541 attcgcttcg tggccggggg cgtgcgctgc cgggctgccg tcggcccggg tgctgtcgaa
    12601 ggccggtgtc cattggcccg cgggcaggcg gaagcggcac gcgtcggccg cggggttgat
    12661 gagcagcagc acgctgcnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnntcc
    12781 ggcgacgacg tggcggggag ggacacgccc ccgagcccgg ccgtgctcga cgcttggccg
    12841 ggcgggtgca gcaggatcgc caacgcgcgc tcgcgcgggt cgttccagtc cgcggcctgc
    12901 agttcggcac cgtcggggcg cagccagcgt acgctcgccg cctcgccgtg ctccggtcca
    12961 cgcagccaat tggcctggcg cagcgcgggg tgggccgcgc gcagggcgag cagccgctgc
    13021 acacaggcga gcagcgcgcg gtcggccccc gcccagtcca gccaggtcgt ctcgttgtcc
    13081 tggcagtagg cgttgttgtt gccgccctgg ctgtggccga gttcgtcgcc ggcgagcagc
    13141 atcggcgtgc cctgggcgag cagcaggctg gcgagcaggg cgcgctgcag gcgggcgcgc
    13201 agggcgagca cgacggggtc gtcggtcggg ccttcgacgc cgcagttcca cgagtggttg
    13261 tgcgcatggc cgtcgcggtt gtgctcgccg ttggccgcgt tgtggcggtg gtcgtggctc
    13321 accaggtcgc gcaggccgaa gccgtcgtgc gcgcacagga agttgatgct ggccgtgggg
    13381 gcgcggcggt cgtggtcgaa ctcggccgcc gagcccgcga agcggtgggc gaacgccccg
    13441 cggtcgcccc cgccgcacag ccaccacgcg cgcatcgtgt cgcggaagcg gtcgttccac
    13501 tccatccagc cgggcgcgaa cccgcccagc cggtagccgt cggggccgag gtcccagggc
    13561 tcggcgatcc atttcaggcg ggcgagcagc gggtcggcgc cgatggcggc aaacagcgcc
    13621 gcgccggcat cgaagtggcc gcggcggtcg cgcccggtag tgaccgcgag gtcgaggcgg
    13681 aagccgtcca cgcggtagcg cgtggcccag tggcgcagcg cgcccacgac cagctcgacc
    13741 atgcgcggct cgcccaggtt caccgcgttg ccgcaaccgc tccagtcgcg gtagcgcgcg
    13801 gggtcctgcg ggtcgaggtg gtaggcgcgc gcgttggcca gcccgcgcag cgatagcagc
    13861 ggcccgtcgg cgtcgagttc ggcggtgtgg ttgaagacga cgtcgagcac cacctcgaag
    13921 ccggcggcgt gcagcgcgtc gatcgcctcg gcgagttcgt cggccggggt ggtgcccgcc
    13981 cgtccgctcc cgtagcgcgg ctcgggcgcg agccaggctg cgggcgcgta gccccagtgg
    14041 ttggcgaggc cgcgccgctg cagcgccgcc tcgtcggcgc ggaagtgcag cggcagcagg
    14101 ctcagcgtgg tgatgccgag cgcgcggtag tgctcgagca tcaccgggtg ggcgagggcg
    14161 ccgtagctgc cgcgcagcgc gggcgggagg ccggggtggc gcatcgtcag cgcgcgcacg
    14221 tgggcctcgt agagcaccgt gcgatcgcgc gggatgcggg ggcggggagg gcgtccggcc
    14281 gtctccatgg ggatcggcgc gcgcacgatg gggacaggca ctcgtgcctt gggggcgaag
    14341 gcggcgttgt cgcgcgcgtc gggcaggcgc ggatcgtcgc tgcgggtggc gcggaacgcg
    14401 tccagctgcg ccgcgagctc cgcgtcgtcg gctggtcccg gtccctggcg accgtagctg
    14461 ccgaccactt cctgcgccca ggggtcgagc agcagcttgg ccgggttgaa ccagtggccg
    14521 cgccgcggcg cccaaggccc gtgggcgcgc aggccataca ccaggcctgc ccgggcggcg
    14581 ggcaggaagc cgtgccagac gccctcgctg cacgacggca gcgcgaggcg acacagttcc
    14641 tcgcgaccct ctgcgtcgaa gaggcagagc tcgatcgctt cggcgtccgg cgcccacacg
    14701 gcgaagttca ccccggcctc gacggcgtcc tcggccaggc tggcaccgag cggccacggc
    14761 tgtcccggac gcagcaccgg ggtgccctcc gcgccggccg gggggatgcg atccacggcc
    14821 aaggcgacac gatccgccgc cgcgccgggg ctcgcgccgc cagggtcgga ccggtggcgg
    14881 aggatcggga gggagtcggg gagcggggcg ctcatcgctg cggtctcctg ggccgtgcgt
    14941 ccatgcgagt cagtcctcgt gcacgaacat cgccacgccc agcggcggca ggcgcagcac
    15001 catcgactgc gcctcgccct gccagggcac ggactcggct ggcagcgtgc cgttggtgac
    15061 gcccgaaccg ccatacaccg catcgtcggt gttgatgagc tcgcgccagg tgcccgccgc
    15121 cggcacgccg atgcgccagc cctcgcgcgc caccggggtg aagttgcacg ccaccaccac
    15181 accgcggccg tcgcgcgcgc ggcgctcgaa gaccagcacc gagtgcgccg cgtcgtcgtg
    15241 ggagatccag cggaaaccgg cgctcgccgt gtccagctcg tacagcgccg gatggctgcg
    15301 cagcacgcgg ttgaggtcgc gcaccaggcg ctgcatgccg gcgtgtgcgg gttgcccgag
    15361 cagcgtccag ggcaggctgg catcggcgtt ccattcggcc cacggcgcga actcgcagcc
    15421 catgaagagc agcttcttgc ccggatgcgc ccacatgtag ccgtagagca ggcgcaggtt
    15481 ggcgaacttc tgccagtcgt cgcccggcat cttggcgagc agcgagccct tgccgtgcac
    15541 cacctcgtcg tgcgacagcg gcagcacgaa gttctcgctg aaggcataca ccagcgagaa
    15601 gcgcagctgg tcgtggtggt gcctgcggtg caccgggtcg cgcgccaggt aggccagcag
    15661 gtcgttcatc cagcccatgt tccacttgta gtggaagccc agtccgccgc cctgcaggtc
    15721 gggcgagggc gggcggctga cgccggggaa ggcggtcgat tcctccgcga gcgtgatcgc
    15781 ctcggggcgc tgcgtgccga cgaggtggtt catgcgccgc aggaagtcga tcgcctccag
    15841 gttctctcgt ccgccgaagc ggttcggcac ccactcgccg gccttgcggc tgtagtcgcg
    15901 gtacagcatc gaggccaccg catccacccg caggccgtcg gcgccgaagc gctcgatcca
    15961 gtacagcgcg ttgctggcga ggtagttgcg cacctcggcg cggccgtagt tgtagatcag
    16021 cgtgttccag tcctggtgga agccttcgcg cgggtcggcg tgctcgtaca ggtgggtgcc
    16081 gtcgaactcg gccaggccgt gcgcgtcgct cggaaagtgc gccggcaccc agtcgaggat
    16141 cacccccagc ccggccgcgc gcgcagcgtc ggtgaaggcg cgaaaatcct caggggtgcc
    16201 gaagcgcgcg ctcggtgcgt acagcccggt gggctggtag ccccaggagc cgtcgaaggg
    16261 gtgctcgtgc accggcatta gttcgagatg ggtgaagccg agctcgactg cgtagggcac
    16321 caggcgctcg gcgagctcgc ggtaggacag ccagccgccg tcctccttgc gctgccagga
    16381 gccgagatga acctcgtaga tgctgatcgg cgcgtcgagc gcgttgacgc gccggcggct
    16441 ctcgtcgatc gccagcccgg gcagcaggcg ctgcaccacc gaggcggtat gcgggcgcag
    16501 ctcggcgcgg aaggcgaagg ggtcggcctt gaggcggacg acgccgtcgg caccgaggac
    16561 ctcgtacttg tagagctcgc cctcgccgat gccgggcacg aagatctccc acaccccgca
    16621 ctcgcggcgg tgccgcatca tgtggcggcg cccgtcccag gcgttgaagc cgccgaccac
    16681 cgagacccgg cgcgcgttgg gtgcccacac cgcgaagcgc gtgccggcca ccccgtctac
    16741 cgtcaccggg tgcgcaccca gccactcgta ggggcggtga tggctgcctt cggcaagcag
    16801 ccagacgtcg agatcctcga tgagcgcgcc gaagcggtag gcgtcgtcga agtgcgtctc
    16861 gccgccgtcg tcccagtgca cgtgcaggtg gtagcgcagc ggcagtgcgc gtgcagggag
    16921 cgcgccgacg aagagggggg agccgtcctg gggctgcagc tcgagcagca tcttgccgtc
    16981 gtgatcgagc gccacgacct ggcgggcgcc gggcagcagc gcgcgcagca ccacgccgcc
    17041 cgcgaccgca tgcgcgccga gcagcgcgaa ggggtcggga tgactcgcct gcagcaagga
    17101 ctgcaaggac tctggggcca cccgggcgag gtccgggttc atcgcctgca aggaattcgc
    17161 tacaacgctc tttcgcgttg cggccctgcc ggtctgcttt tcgccgcgca tctgcgcctc
    17221 tccggttcga gtgccgggcg tttcttcgtt gcgtcgcagc gaagcacgcc cgacagcccc
    17281 aaggataaaa ctttcgcgtg ttttgcgctg caacgaatcg cccccaaagc cgtgcgtccg
    17341 gaacgttcca gcccccgacg cggctaccgc cgcgcccaca caaaccgcca cgcgcccaca
    17401 gcccctgtag gagcggcggc agccgcgaat cgggcggtgc ggcgggcgac gcggt
//
LOCUS       DAOTIN010000065        17224 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_4002_length_17224_cov_8.516454, whole genome shotgun sequence.
ACCESSION   DAOTIN010000065 DAOTIN010000000
VERSION     DAOTIN010000065.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 17224)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 17224)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17224
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4002_length_17224_cov_8.516454"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..>1067)
                     /locus_tag="P5537_10660"
     CDS             complement(<1..>1067)
                     /locus_tag="P5537_10660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-3' exonuclease H3TH domain-containing
                     protein"
                     /protein_id="HRV78544.1"
                     /translation="MPTLLLVDGSSYLYRAFHALPDLRNSQGEPTGAIRGVLSMLRRL
                     ESDYKAEFRACVFDAKGKTFRDDWYPEYKSHRPPMPDDLRAQIAPLHEAVQAEGWPLL
                     SVEGVEADDVIGTLTRQALERGWEVVISTGDKDLTQLVRPGVRWVNTMSEEVLDEAGV
                     EAKFGVPPERIVDYLALVGDTVDNVPGVEKCGPKTAVKWLTEYGTLENLVANADKVGG
                     KVGENLRRHLDFLPLGKRLVTVATDVELPVGLDELPAREDDKAALRALYERFEFKSWL
                     KDLDGGAESVAASKAATDSRRFAASAAPAWGGEPAGAAGAANAESGSGQAAPSDAHRK
                     GYVAILDWPTFDVWLAKISAAA"
     assembly_gap    1068..1167
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            1181..1906
                     /locus_tag="P5537_10665"
     CDS             1181..1906
                     /locus_tag="P5537_10665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004376035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HRV78545.1"
                     /translation="MTAKDKLPRSVPDSTAPRYNARESWRIFGIMAEFVEATERLAAI
                     RPAVSIFGSARTPPDHMYYMLTERIARLLSDSGFAVISGGGPGIMEAANKGAFFGKSP
                     SVGLNIQLPLEQAANPYQDISQTFQHFFARKFMFVKFATAYVVMPGGFGTLDELLEAM
                     TLVQTKKSRKIPIILVHRPFWQGLLDWLRDRLVAEGMINPEDLDLIQVIDEPEEVVDA
                     IFKHYERRGFQPLPAEREMMLNL"
     gene            1961..2281
                     /locus_tag="P5537_10670"
     CDS             1961..2281
                     /locus_tag="P5537_10670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004376031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2782 domain-containing protein"
                     /protein_id="HRV78546.1"
                     /translation="MRRTLIALLLAAAVPAFAQQPANLEPIPEPPPMPAEGAADEPEV
                     TIVKRGEDTVTEYRMRGKLYMVKVTPPHGVPYYLIDKEGNGQMVRHDGTPDLAVPMWV
                     IKSW"
     gene            2278..2844
                     /locus_tag="P5537_10675"
     CDS             2278..2844
                     /locus_tag="P5537_10675"
                     /EC_number="3.2.2.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033958 - DNA-deoxyinosine glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006285 - base-excision repair, AP site
                     formation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-deoxyinosine glycosylase"
                     /protein_id="HRV78547.1"
                     /translation="MSTTAAPLVRSFAPQFRADARVLVLGSMPGTASLAAAQYYAHPR
                     NAFWPIMGALFGAGPELPYAQRLERLASAGIALWDVIGRCERAGSLDSAIAPASIEAN
                     DFAGLFAACPGIDHVFFNGTAAETAFRRHVRGRIALPPLQFARLPSTSPAHAARGLGA
                     KLAAWQAVKAAAQRAAAARIDTPAAQAA"
     gene            2876..3832
                     /locus_tag="P5537_10680"
     CDS             2876..3832
                     /locus_tag="P5537_10680"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004389250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004413 - homoserine kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HRV78548.1"
                     /translation="MSVFTPVPESVLADWLKDYAIGRLVELKGISAGVQNSNFFVTTT
                     LGRYVLTLFEGIPRAELPYYLHLMAHLARHGLPVPGPIANRHNEYLGTLQERPAALVV
                     RLSGGSEMAPGLPHCEKVGAMLAGLHLAGQSYGRRQENPRGAAWRAATAQVVRPFLPA
                     DEQALLDAELAFQATIDVAALPAGAIHADLFRDNVLWDTDAGGDVRIGGVIDFYFAGY
                     DALLFDVAVTVNDWCSTPDGGLDGARAAALLDAYHAERPFTDAERAAWPAMLRAAALR
                     FWMSRAADFHLPRTGEMVLVKDPNEYRDILRLRIATVPPLPR"
     gene            3867..4823
                     /locus_tag="P5537_10685"
     CDS             3867..4823
                     /locus_tag="P5537_10685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BPSS1780 family membrane protein"
                     /protein_id="HRV78549.1"
                     /translation="MNATLPPPRRPHPPPPAPGDVVPGHALDWLAAGWRIFMRAPLVW
                     ALQALIFFVILAALGMVPFLGWAAAPVTLPVLVAGMLSGARALDRGEPLHVGQLFDGL
                     RQHAGNLLLVGLFHLLGLLLAALAAAAIGGSAILTGAAAGALGAIAGAGVAAGGMMLG
                     VVVFTVLWALLMMALWFAPALVMLHEVAPLDAMRLSARACFHNLLAFVVLAALLYVLV
                     WVAMIPAGLGMLVLVPVIAGALYAAWKETFSPLLPAPAAAPDHTPDEASAQEATCDTT
                     PASPALLPPPSDNATDDVGTNTAPPAPEPGPSPGPADEPPKP"
     gene            4837..5640
                     /locus_tag="P5537_10690"
     CDS             4837..5640
                     /locus_tag="P5537_10690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BPSS1780 family membrane protein"
                     /protein_id="HRV78550.1"
                     /translation="MQARQLPMPRGWAWLREGLQLWRRNPALLTFATFGYLLSIIVIS
                     LVPLLGQLVASLLMPALSVGVLNACRAIDGGRKTGPDVLFSGFKSNLQGLVVVGGLYL
                     AATLVVLMLVMLVDDGSLAAVMRGEDMDTQAAADSSLGFTLAVGLALSTPVMMAYWFA
                     PALAGWWKLPAPKAMFFSFYACLRNWRPFVAYALGLAIFAGLLPGLVVAVLGLLSPTL
                     GSLAALPVPLIVLPIVFASFYTATRDVFGLPENNPARDPVALDDARDGD"
     gene            5630..6340
                     /gene="nadD"
                     /locus_tag="P5537_10695"
     CDS             5630..6340
                     /gene="nadD"
                     /locus_tag="P5537_10695"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HRV78551.1"
                     /translation="MATEFVPAPAGLAWAPAAEAPVGVLGGTFDPIHTGHLRLAEEAR
                     EALGLGSVRLIPAGQPPHRGEPGSTAEDRLAMARLAAAGNPGFSVDDGEVRARQKSYT
                     VLTLERLRAELGPQRSLVLILGADAFAGLPTWHRWTDLFALAHIAVANRPGYAPHGRR
                     WPATLSPELDAACAGRHTADPADLRHAPAGRVVPFDMTPLAISASLIRDLVRNGHSAR
                     YLLPESVLDYIAAHHLYR"
     gene            6372..6719
                     /gene="rsfS"
                     /locus_tag="P5537_10700"
     CDS             6372..6719
                     /gene="rsfS"
                     /locus_tag="P5537_10700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HRV78552.1"
                     /translation="MDTPTLEKIVVAALEDIKARDIEVIDTSKHTPLFDRIVVASAES
                     GRQTRALAQNVHDKVKEAGGEIIGTEGQETGEWVLVDLGNIVVHVMQPAVRAHYKLEE
                     LWNTPPSSRRNAA"
     gene            6817..7287
                     /gene="rlmH"
                     /locus_tag="P5537_10705"
     CDS             6817..7287
                     /gene="rlmH"
                     /locus_tag="P5537_10705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011767331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HRV78553.1"
                     /translation="MKLLIIAVGHRMPAWVQAGFDEFARRMPRELTLQLVEVKAEPRS
                     GGKTVEAMMAAEAARIEAALPPRCRRVILDERGADLTTVALARRLESWQGEGDDVALI
                     VGGPDGLAPAFKASAHEAVRLSSLTLPHALVRPLLAEALYRAWTVLKNHPYHRE"
     gene            7425..8045
                     /locus_tag="P5537_10710"
     CDS             7425..8045
                     /locus_tag="P5537_10710"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maf family protein"
                     /protein_id="HRV78554.1"
                     /translation="MTLTPRIYLASKSPRRRDLLRQIGVNFDVLTFRAGERGEDADVD
                     ETPLPGEAVERYVERLALAKAQAGMRRVLWRKLLPHPVLAADTTLEVDGEIVGKPHDA
                     AEAHAILERLSGRRHRVLTAVAMSDGERTRSRLSVSEVAFRSLGEHDIRRYIATGEPF
                     DKAGAYGIQGHAAIFIEEIRGSYSGIMGLPLFETAALLEIFGHPVL"
     gene            8059..9513
                     /gene="rng"
                     /locus_tag="P5537_10715"
     CDS             8059..9513
                     /gene="rng"
                     /locus_tag="P5537_10715"
                     /EC_number="3.1.26.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004334175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - ribonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease G"
                     /protein_id="HRV78555.1"
                     /translation="MSIEFLINFTPQETRVAVVEQGVVQELHVERTASRGIVGNLYLG
                     KVVRVLPGMQSAFIDIGLERTAFLHVADIWSDRQNGESARPIEKILTEGQSLMVQVLK
                     DPIGTKGARLSTQVSLAGRLLVYLPQEKHIGISQRIEDEAGREALRSRLVALVPEDEP
                     GGFIVRTMAESATDAELAADIAYLRKLWREISGSTVGLFPPKLLHEDLGLGQRTLRDL
                     VTDETSRIRVDSRENFQKLSAFAAEYTPQVLPLLEHYSGERPLFELYSVEEEIQKALA
                     RRVDLKSGGYLIIDQTEAMTTVDVNTGGFVGARNFDDTIFKTNLEASQAIARQLRLRN
                     LGGIIIIDFIDMENVEHREMVLEEFRKALSRDHTKMSINGFTALGLVEMTRKRTRESL
                     AHLLCEPCPTCSGRGEVKTARTVCYEILRELLREARQFNAKEFRVLAAPNVIDLFLDE
                     ESQSLAMLSDFIGKKVSLHAEGSYTQEQYDIVLL"
     gene            9660..10223
                     /locus_tag="P5537_10720"
     CDS             9660..10223
                     /locus_tag="P5537_10720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Uma2 family endonuclease"
                     /protein_id="HRV78556.1"
                     /translation="MSNAMARPAPIRVEDYLEGETLTDIKHEYLDGEVVAMGGASARH
                     GLVAGALYGALLPHARRKGCQLFIADMKVRVEHTGQTYFYYPDLMLACAPDDRETYYR
                     RNPCLLVEVLSPSTERIDRREKLFAYQAIPSLREYLLVDPDKRSVEIYRFGDPVRYET
                     CTEGAFRLDCLDVEITLDEVYADAEAP"
     gene            complement(10290..11003)
                     /locus_tag="P5537_10725"
     CDS             complement(10290..11003)
                     /locus_tag="P5537_10725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004383614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV78557.1"
                     /translation="MNAPLLCCRGLEAGYGASRVLFGLDFDIRAGEVVALLGRNGMGK
                     STTIRSIVGGLRPQRGEIVFDGRPIHAERADAIARLGVAIVPEGRQCFPNLTVHEHLV
                     AFAACRNGVAEPWTPARLYALFPRLAERAGHLGNQLSGGEQQMLAIARALSTNPRLLI
                     LDEATEGLAPVIREEIWRCLALLKAQGQTTLVVDKYVDKLLPLADHNLILERGRIAWQ
                     GSSAELDARRELWGRYLGV"
     gene            complement(11000..11749)
                     /locus_tag="P5537_10730"
     CDS             complement(11000..11749)
                     /locus_tag="P5537_10730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004383616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV78558.1"
                     /translation="MSLFRAEGLVKRFGGLLATDHVDLAVEAGEIHALIGPNGAGKST
                     LVNLISGLLPADAGRIVLDGVDLTALAPHARTRAGLARCFQITSVFRNDSVRDNLLLA
                     VQAQAGSSFRCLSRRDAEHALQERAEALAQRAGLAEVLERNAGTLPHGLQKRLDLALA
                     LAARPKLLLLDEPMAGMGPEDSQQMVDLIRSLRSETAILLIEHDMDAVFQLADRISVL
                     VYGKVLTSGDAAHVKGHAEVQAVYLGTEVAT"
     gene            complement(11746..12765)
                     /locus_tag="P5537_10735"
     CDS             complement(11746..12765)
                     /locus_tag="P5537_10735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HRV78559.1"
                     /translation="MQGSTPQNPSSAPGAVAAITHARFPGLARRLPWLVLALLAAFPL
                     LAPALGLEYYVGFVRRVLIVAIAATSLNFILGYGGMAALGHAGFIGVGAYTVVALVEA
                     GFSSAWLAWGSAALVAGLAAAAIGAVSLRTRGVYFIMITLAFAQMLYYLAVSLRTYGG
                     DDGYGLYTPLELGAWLDGAHAQVFYWVVLAIAAAVFALFSRVAHSRYGHALRGIRDNE
                     TRMVALGYPVYGLKLAGFVAAGAVAGLAGGLLASHNAFVSPSIMHWTQSALLLVMVML
                     GGAGRRWGAPLGVALWLTLEEALKLYTDYWHWPLGLLLLLVVFHAPQGVAALLERRGG
                     RESVR"
     gene            complement(12774..13694)
                     /locus_tag="P5537_10740"
     CDS             complement(12774..13694)
                     /locus_tag="P5537_10740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HRV78560.1"
                     /translation="MDAIFVFEQLLNGLGYGLMLFLIAAGLTLVFGIMDTMNLAHGSL
                     YMAGAYVAARVHEASGAFVLAVAVAVGVTVAIAAVVEFVVIRRLYRRDHLVQVLATFG
                     IILIADDAVKAIWGVAPLLASTPAALAGPVDLFQGLPYPSYRLLLIGAGLAVALGLYL
                     LVNKTRVGMLVRAGASNRQMAEHMGVRVGGVFAFVFALGAALAALAGALMAPISAVQI
                     GMGEAILIPALVVIVIGGIGSVRGAFVAALLVGMVDTAGRAFLPPALRAVLPPSVAAD
                     LGPALAGIAMYVLMAAVLTLKPAGLFPARG"
     gene            complement(13848..15014)
                     /locus_tag="P5537_10745"
     CDS             complement(13848..15014)
                     /locus_tag="P5537_10745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004315747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HRV78561.1"
                     /translation="MLQMKKLSVALALYGAAALNVHAADIKVGIALDLSGPFSALGAE
                     ARDGFELAIEKLGGKLGGQPAEFIRNDFGGNPEQANQLVARFLQRDGIHFFTGPIGSN
                     AALAVGPALFAAKVPYLSANPGPSAYAGEKCNPYFFAQYQNDTYDEAAGKVANEKGYR
                     NVVLIAPNYPAGKDHLNGFKRLYKGGVKDEIYTKLGQIDYAAEIAQIRAAKPDAVFFF
                     LPGAMGINFVKQFVGGGLKDIPLIAPGFSADEDVIQAVGEPMLGVLNTAHWTHDLQNP
                     ANTEFVAAFRQKYAGRYPSVYAAMAYDTLMAMDAAVRDVGGKIEDREAVLKALKNPSF
                     KSLRGEFQYGANNFPVQNYYLREVGKDAEGRITNKLVGTTLEKHQDAYVGACKM"
     gene            15214..15813
                     /gene="ruvA"
                     /locus_tag="P5537_10750"
     CDS             15214..15813
                     /gene="ruvA"
                     /locus_tag="P5537_10750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HRV78562.1"
                     /translation="MIGRITGTLLEKNPPQILVDVHGVGYEIDVPMSTFYNLPATGGA
                     VSLHTHFVVREDGHFLFGFATDEERVTFRQLLKVSGVGARMALAVLSGLSVNDLAQAV
                     ALQEAGRLVKIPGIGKKTAERLLLELRDKLGKGLPSMTGVRLAAAPGAAPDAKSDILN
                     ALLALGYNEREALAAMKGLAEDVGVSDGIRQALKALSKG"
     gene            15834..16889
                     /gene="ruvB"
                     /locus_tag="P5537_10755"
     CDS             15834..16889
                     /gene="ruvB"
                     /locus_tag="P5537_10755"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004374647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HRV78563.1"
                     /translation="MIETDKLKAAAPAERLISAAPADRQEDAIERALRPKRLAEYVGQ
                     AKIREQLEIFIQAARKRSEALDHVLLFGPPGLGKTTLAHIVAAEMGVNLRQTSGPVLE
                     RAGDLAALLTNLEPHDVLFIDEIHRLSPVVEEILYPALEDFQIDIMIGEGPAARSVKL
                     DLPPFTLVGATTRAGMLTNPLRDRFGIVSRLEFYTADELAFIVGRSARLLNVEIDDAG
                     ALEIARRARGTPRIANRLLRRVRDYAEVKAGGRITAEVADAALRMLDVDNLGLDLMDR
                     KLLSAMLEKFGGGPVGLDNIAAAIGESTDTIEDVIEPYLIQQGYLQRTPRGRMATHSI
                     WQHFGLAPPRVGGDLFQ"
     gene            16905..>17224
                     /locus_tag="P5537_10760"
     CDS             16905..>17224
                     /locus_tag="P5537_10760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004315750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78564.1"
                     /translation="MRSLQVVMLMLCVLGGLFLLVRAPEFFLPAQWDPSIGRSFDPLA
                     SRLLGAGLLALAAAGAGYIHAMYYTMPRRLPGPAAQRRHFALLLAALVLIGAALARAE
                     PGPNP"
BASE COUNT         2539 a         6456 c         5703 g         2426 t
ORIGIN      
        1 gcggcggcgg agatcttcgc cagccagacg tcgaaggtgg gccagtcgag gatggcaacg
       61 tagcccttgc ggtgggcgtc ggaaggggcg gcctggccgc tcccggactc ggcgttcgcg
      121 gcccccgccg cgcctgcagg ctcaccgccc catgcaggcg cggcggaagc cgcgaaccgg
      181 cgcgaatccg tggccgcctt cgaggccgcg acgctctccg ccccgccatc cagatccttc
      241 agccacgact tgaactcgaa gcgctcgtag agcgcgcgca gcgccgcctt gtcgtcctcg
      301 cgcgcgggca gctcgtcgag acccaccggg agctcgacgt cggtcgccac cgtcaccagc
      361 ctcttgccga gcggcaggaa gtccaggtgc cgacgcaggt tctcgccgac cttgccgccc
      421 accttgtcgg cgttggcgac caggttttcg agggtgccgt actcggtcag ccacttcacc
      481 gcggtcttgg ggccgcactt ctccacgccc ggcacgttgt ccaccgtgtc gccgaccagc
      541 gcgaggtagt cgacgatgcg ctccggcggc acgccgaact tggcctccac gccggcctcg
      601 tccagcacct cctcgctcat ggtgttcacc cagcgcaccc cggggcgcac gagctgggtg
      661 aggtccttgt cgccggtcga gatcaccacc tcccagccac gctcgagcgc ctggcgggtg
      721 agcgtgccaa tgacgtcgtc ggcctccacg ccctccaccg acagcagcgg ccagccttcc
      781 gcctgcaccg cctcgtgcag cggcgcgatc tgcgcgcgca ggtcgtcggg catcggcggg
      841 cggtgcgact tgtattcggg ataccagtcg tcgcggaagg tcttgccctt ggcgtcgaag
      901 acgcaggcgc gaaattctgc cttgtagtcg ctttccagcc gccttagcat cgacagcacc
      961 ccccggatcg cccccgtcgg ctcgccttgc gaattgcgca gatcgggcag ggcgtggaag
     1021 gcgcggtaga gatagctgga gccgtcgacg agcagcaggg tgggcatnnn nnnnnnnnnn
     1081 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1141 nnnnnnnnnn nnnnnnnnnn nnnnnnnaga gaacaacaac atgaccgcga aagacaaact
     1201 cccccgcagc gtgcccgaca gcaccgcgcc gcgctacaac gcgcgcgaat cctggcggat
     1261 cttcgggatt atggcagagt tcgtggaggc gaccgaacgc ctggccgcga tccgccccgc
     1321 ggtctcgatc ttcggcagcg cacgtacgcc gcccgaccac atgtactaca tgctcaccga
     1381 aaggattgcc cgactgctgt cggattcggg cttcgcggtg atctcgggcg gcggcccggg
     1441 catcatggag gcggccaaca agggcgcctt cttcggcaag agcccctcgg tcgggctcaa
     1501 catccagctg ccgctggagc aggccgccaa tccctaccag gacatctcgc agaccttcca
     1561 gcacttcttc gcgcgcaagt tcatgttcgt gaagttcgcc accgcctacg tggtgatgcc
     1621 ggggggcttc ggcacgctcg acgagctgct cgaggcgatg acgctggtgc agaccaagaa
     1681 gagccgcaag atcccgatca tcctggtgca tcgtccattc tggcaggggc tgctcgactg
     1741 gctgcgcgac cgcctggtgg ccgaaggcat gatcaacccg gaagacctcg acctgatcca
     1801 ggtgatcgac gagcccgagg aggtggtcga tgcgatcttc aagcactatg agcggcgtgg
     1861 cttccagcct ctgccggcgg aacgggagat gatgctgaac ctgtgaatgc agccccccgc
     1921 gcattaccgg ctagaattgc agcatcttcc ggagaacatc atgcgtcgca ccctgatcgc
     1981 cctgttgctg gctgctgccg tgccggcctt cgcccagcag cccgcgaacc tcgaaccgat
     2041 ccccgagccg ccgccgatgc ccgccgaggg cgcggccgac gagcccgagg tcaccatcgt
     2101 caagcgcggc gaggacacgg tcaccgagta ccgcatgcgc ggcaagctct acatggtcaa
     2161 ggtcacgccg ccgcacggcg ttccctacta cctgatcgac aaggaaggca acggccagat
     2221 ggtgcgccac gacggcacgc ccgacctcgc cgtgccgatg tgggtgatca agtcctggtg
     2281 agcacgaccg ccgcaccgct ggtgcgcagc tttgccccgc agttccgcgc cgacgcgcgc
     2341 gtgctggtgc tcggcagcat gccgggcacg gcctcgctcg ccgccgcgca gtattacgcg
     2401 cacccgcgca acgccttctg gccgatcatg ggcgcgctct tcggcgccgg gccggagctc
     2461 ccctacgcac agcgcctcga gcgcctcgcg tccgccggca tcgcgctgtg ggacgtcatc
     2521 ggccgctgcg agcgcgccgg cagcctggac agcgcgatcg cgcccgcgag catcgaggcc
     2581 aacgacttcg ccggcctctt cgccgcctgc cccggcatcg accacgtctt cttcaacggc
     2641 accgccgccg agaccgcctt ccgccgccac gtacgcggcc gcatcgcgct gccgccgctg
     2701 cagttcgccc gcctgccctc gaccagcccg gcgcacgccg cacgcgggct cggggccaag
     2761 ctcgccgcct ggcaggcggt gaaggcggcc gcgcagcgcg ccgccgcggc gcgcatcgac
     2821 accccggccg cccaggccgc ctgaacccaa cccgaccgcc tcacccggag tccgcatgtc
     2881 cgtcttcacc cccgttcccg aatccgtgct cgccgactgg ctcaaggact atgccatcgg
     2941 ccgcctggtg gaactcaagg gcatctcggc cggcgtccag aacagcaact tcttcgtcac
     3001 caccacgctc gggcgctacg tgctcacgct cttcgaaggc atcccgcgcg ccgagctgcc
     3061 ctattacctg cacctgatgg cccacctcgc gcgccatggc ctgccggtgc cgggtccgat
     3121 cgccaaccgc cataacgaat acctcggcac cctgcaggag cgccccgccg cgctggtggt
     3181 gcggctgtcg ggcggctccg agatggcccc cggcctgccg cactgcgaga aggtcggcgc
     3241 catgctcgcc ggcctgcacc tggccggcca gtcctacggc cgccgccagg agaacccgcg
     3301 cggcgccgcc tggcgcgccg ccaccgcgca ggtggtgcgc cccttcctgc ccgccgacga
     3361 gcaggccctg ctcgacgccg agctcgcctt ccaggccacc atcgacgtcg ctgccctgcc
     3421 cgccggcgcg atccacgccg acctcttccg cgacaacgtg ctgtgggaca ccgacgccgg
     3481 tggcgatgtg cgcatcggcg gcgtcatcga cttctacttc gccggctacg atgcgctgct
     3541 cttcgacgtc gcggtcaccg tgaacgactg gtgctccacg cccgacggcg gcctcgacgg
     3601 cgcacgcgcg gcggccctgc tcgacgccta ccacgccgag cgccccttca ccgatgccga
     3661 gcgcgcagcc tggccagcca tgctgcgcgc cgccgcgctg cgcttctgga tgtcgcgcgc
     3721 agccgacttc cacctgccgc gcacaggcga gatggtgctg gtcaaggacc cgaacgagta
     3781 ccgcgacatc ctgcgcctgc gcatcgccac ggtgccgccc ctgccgcgct gacgccgccc
     3841 cgcgcgccct gtccggaccg acgccgatga acgccaccct gcccccaccc cgccgcccgc
     3901 atccgccgcc gcccgccccg ggcgacgtgg tgcccggcca cgccctcgac tggctcgccg
     3961 cgggctggcg catcttcatg cgggcgccgc tggtgtgggc gctgcaggcg ctgatcttct
     4021 tcgtgatcct cgccgcgctc ggcatggtgc ccttcctcgg ctgggcggcc gcaccggtga
     4081 ccctgccggt gctggtcgcc ggcatgctct ccggcgcgcg tgcgctcgat cgcggcgagc
     4141 ccctccacgt cggccagctc ttcgacggcc tgcgccagca tgccggcaac ctgctgctgg
     4201 tcggcctctt ccacctcctc ggcctgctgc tcgctgcgct ggccgcggcg gcgatcggcg
     4261 gcagcgcgat cctcaccggc gcagccgcgg gcgcgctcgg cgcgatcgcc ggagcaggcg
     4321 tcgccgccgg cggcatgatg ctcggcgtgg tggtgttcac cgtgctgtgg gccctgctca
     4381 tgatggcgct gtggttcgcc ccggcgctgg tgatgctgca cgaggtcgcg ccgctggacg
     4441 cgatgcggct gtccgcgcgc gcctgcttcc acaacctgct cgccttcgtg gtgctcgccg
     4501 cgctgctcta tgtgctggtg tgggtggcga tgatcccggc cgggctgggc atgctggtgc
     4561 tggtgccggt aatcgccggc gcgctctacg cggcgtggaa ggagaccttc tcgccgctgc
     4621 ttcccgcccc cgcggccgcc cccgaccaca cgccggatga agcctccgcg caggaggcga
     4681 cgtgcgacac caccccggcc agccccgcac tgctcccgcc gccgagcgac aacgcgacgg
     4741 acgacgtcgg caccaacacc gcgccacccg ctcccgagcc tggtccctcg cccggtcctg
     4801 cggacgagcc gcccaaaccc tgacccctgg aaaccaatgc aagcacgaca actccccatg
     4861 ccgcgcggct gggcctggct gcgcgaaggc ctgcagctgt ggcggcgcaa ccccgcgctg
     4921 ctcaccttcg caaccttcgg ctacctgctc tcgatcatcg tcatcagcct ggtgccgctg
     4981 ctcggccagc tcgtcgcctc gctgctgatg ccggcgctct cggtcggcgt gctcaacgcc
     5041 tgccgcgcca tcgacggcgg gcgcaagacc ggtcccgacg tgctcttctc cggcttcaag
     5101 tccaacctgc agggcctcgt ggtggtcggc ggcctctacc tcgcggccac cctggtggtg
     5161 ctgatgctgg tgatgctggt cgacgacggc agcctggccg cggtgatgcg cggagaggac
     5221 atggacacgc aggccgcggc cgactcctcg ctcggcttca ccctggcggt cggcctcgcg
     5281 ctgagcaccc cggtgatgat ggcctactgg ttcgcgcccg cgctcgcggg ctggtggaag
     5341 ctgcccgcgc ccaaggcgat gttcttcagc ttctacgcct gcctgcgcaa ctggcggccc
     5401 ttcgtcgcct acgcgctcgg gctggcgatc ttcgccggcc tgctgcccgg cctggtggtc
     5461 gcggtgctcg gcctgctctc gcccacactc ggcagcctgg ccgcgctgcc ggtgccgctg
     5521 atcgtgctgc cgatcgtgtt cgcgagcttc tacaccgcca cccgcgacgt cttcggcctg
     5581 cccgagaaca acccggcgcg agatccggtc gccctcgacg acgcgcgcga tggcgactga
     5641 gttcgtgccc gcgccggccg ggcttgcctg ggcgcctgca gccgaagcgc cggtcggcgt
     5701 gctcggcggc accttcgacc ccatccacac cggccacctg cgcctcgccg aggaggcgcg
     5761 cgaggcgctc ggccttggca gcgtgcgcct catccccgcc ggccagccgc cgcaccgcgg
     5821 cgaacccggc agcacggccg aggaccgcct cgccatggcg cggctcgccg ccgccggcaa
     5881 cccgggcttc agcgtggacg acggcgaggt gcgcgcccgg cagaagagct acaccgtgct
     5941 caccctcgag cgcctgcgcg ccgagctcgg cccgcagcgg tcgctggtgc tgatcctcgg
     6001 cgccgacgcc ttcgccggcc tgccgacctg gcaccgctgg accgacctgt tcgcgctcgc
     6061 ccacatcgcg gtcgccaacc gccccggcta cgcgccccac ggccggcgct ggcccgccac
     6121 cctgtcgccc gagctcgacg ccgcctgtgc cggccgccac accgccgacc ccgcggatct
     6181 gcgccatgcg cccgccggcc gcgtcgtccc cttcgacatg acgccactgg cgatctcggc
     6241 ctcgctgatc cgcgatctcg tgcgcaacgg ccacagcgcc cgttatttgc tgcccgaatc
     6301 ggttctcgac tatattgccg cgcaccatct ctaccgctga gcgcctcgcg ccagcccctc
     6361 acaggacccg aatggacacc cccaccctcg aaaagatcgt tgtcgccgcg ctcgaagaca
     6421 tcaaggcacg cgacatcgaa gtcatcgaca cctcgaagca caccccgctc ttcgaccgca
     6481 tcgtcgtcgc cagcgccgag tccggccgcc agacccgcgc gctcgcgcag aacgtgcatg
     6541 acaaggtcaa ggaggccggc ggcgagatca tcggcaccga aggccaggag accggcgagt
     6601 gggtgctggt cgacctcggc aacatcgtcg tgcacgtgat gcagcccgcg gtgcgcgcgc
     6661 actacaagct cgaggagctc tggaacaccc cgccgtccag ccggcgcaac gccgcctgac
     6721 gggcagccgc cctcgcgagc ggccgccggc gcattgcgcg ggcgacgctc gcacgttgcg
     6781 acgcatgctc gcccgcgagc gcttgcagcc tccaccatga aacttctcat catcgccgtc
     6841 ggccaccgca tgcccgcctg ggtgcaggcc ggcttcgacg agttcgcgcg ccgcatgccg
     6901 cgcgagctga cgctgcagct cgtggaggtc aaggccgagc cgcgcagcgg cggcaagacg
     6961 gtcgaggcga tgatggccgc cgaggccgca cgcatcgagg cggccctgcc gccacgctgc
     7021 cggcgcgtga tcctcgacga gcgcggcgcc gacctcacca ccgtggcgct cgcgcgcagg
     7081 ctggagtcct ggcagggcga gggcgacgac gtcgcgctga tcgtcggcgg ccccgacggc
     7141 ctcgcgcccg cgttcaaggc cagcgcccac gaggccgtcc gcctctccag cctcaccctc
     7201 ccccacgccc tggtgcgccc gctgctggcc gaggccctgt accgcgcgtg gacggtgctc
     7261 aagaaccacc cctaccaccg cgagtagcgc aagcggtgcg ggctccgggt ggctgtgcga
     7321 tcgccccggg tcggcgggtg gccggcggtg aaacccgtta gaatcgcgcc acccgagccc
     7381 gaccggcgcc gaccggcgct gcggatcccg cggaaagcca tgccatgacc ctcacgccgc
     7441 gcatctacct cgcctccaag agcccccgcc gccgcgacct gctgcgccag atcggcgtca
     7501 atttcgacgt gctgaccttc cgcgccggtg aacgcggcga ggacgccgac gtcgacgaga
     7561 ccccgctgcc cggcgaggcg gtcgagcgct acgtcgaacg cctcgccctc gccaaggccc
     7621 aggctggcat gcggcgggtg ctgtggcgca agctgctgcc gcacccggtg ctggcggccg
     7681 acaccacgct cgaggtggac ggcgagatcg tcggcaagcc gcacgacgcc gccgaggccc
     7741 atgccatcct cgagcgcctc tccggccgcc gccaccgcgt gctgaccgcg gtcgcgatga
     7801 gcgacggcga gcgcacgcgc agccggctgt cggtcagcga ggtcgccttc cgctcgctcg
     7861 gcgagcacga catccgccgc tacatcgcca ccggagagcc cttcgacaag gccggcgcct
     7921 acggcatcca gggccacgcc gcgatcttca tcgaggagat ccgcggcagc tactcgggga
     7981 tcatgggcct gccgctgttc gagaccgccg ccctgctcga gatcttcggc caccccgtcc
     8041 tgtgagcgca ccccgtccat gagcatcgaa ttcctcatca acttcacccc gcaggagacc
     8101 cgcgtcgcgg tcgtcgaaca gggcgtggtg caggagctgc acgtcgagcg caccgccagc
     8161 cgcggcatcg tcggcaacct ctacctcggc aaggtcgtgc gcgtgctgcc cggcatgcag
     8221 tcggccttca tcgacatcgg cctcgagcgc accgccttcc tgcacgtggc cgacatctgg
     8281 agcgaccgcc agaacggcga gagtgcgcgc ccgatcgaga agatcctcac cgagggccag
     8341 agcctgatgg tgcaggtgct caaggacccg atcggcacca agggcgcgcg cctgtccacc
     8401 caggtcagcc tcgccggccg cctgctcgtc tacctaccgc aggaaaagca catcggcatc
     8461 tcccagcgca tcgaggacga ggccgggcgc gaagccctgc gcagccgcct ggtggcgctg
     8521 gtgcccgagg acgagccggg cggcttcatc gtacgcacca tggccgaatc cgccaccgat
     8581 gccgagctcg ccgccgacat cgcctacctg cgcaagctgt ggcgcgagat ctccgggtcg
     8641 acggtcggcc tctttccgcc gaagctgctg cacgaggacc tcggcctggg ccagcgcacc
     8701 ctgcgcgacc tcgtcaccga cgagacctca cgcatccgcg tcgactcgcg ggagaacttc
     8761 cagaagctct ccgccttcgc cgccgaatac acgccgcagg tgctgccgct gctcgagcac
     8821 tacagcggcg agcgcccgct cttcgagctc tacagcgtcg aggaggagat ccagaaggcg
     8881 ctcgcccgcc gggtggatct caagtccggc ggctacctga tcatcgacca gaccgaggcg
     8941 atgaccacgg tcgacgtcaa caccggcggc ttcgtcggcg cgcgcaactt cgacgacacc
     9001 atcttcaaga ccaacctcga ggccagccag gcgatcgccc gccaactgcg cctgcgcaac
     9061 ctcggcggca tcatcatcat cgacttcatc gacatggaga acgtcgagca tcgcgagatg
     9121 gtgctggagg agttccgcaa ggcgctgtcg cgcgaccaca ccaagatgag catcaacggc
     9181 ttcactgcgc tgggcctggt ggagatgacg agaaagcgca cccgcgagtc gctcgcccac
     9241 ctgctgtgcg agccctgccc cacctgcagc ggccgcggcg aggtgaagac cgcgcgcacg
     9301 gtgtgctacg agatcctgcg cgagctgctg cgcgaggcgc gccagttcaa cgcgaaggag
     9361 ttccgcgtgc tcgccgcgcc caacgtcatc gacctcttcc tcgacgagga gagccagtcg
     9421 ctggcgatgc tgtcggactt catcggcaag aaggtctcgc tgcacgccga gggcagctac
     9481 acccaggagc agtacgacat cgtgctgctg taggcgcggc ggggcgcccg cgcgcagcgc
     9541 ccgtcgggcc ggcgtcgcgc gccgctgcgc gatccgccgg gcgcgctggt cgacaccagg
     9601 actgtcgccg tatcatttgc cgtcgatctg ccgccccacc tgccgcaacg gaggccctca
     9661 tgagcaacgc catggcacgt cccgccccga tccgcgtcga ggactacctc gaaggcgaga
     9721 ccctgaccga catcaagcat gaatacctcg acggcgaggt ggtggcgatg ggcggcgcca
     9781 gcgcgaggca tggcctggtc gcgggtgccc tttacggcgc actcctcccg cacgctcgcc
     9841 gcaagggctg ccagctcttc atcgccgaca tgaaggtccg ggtcgagcac accggccaga
     9901 cctatttcta ttaccccgac ctgatgctgg cctgcgcgcc cgacgaccgc gagacctatt
     9961 accgccgcaa cccctgcctg ctggtggagg tgctgtcgcc gagcaccgag cgcatcgacc
    10021 gccgcgagaa gctcttcgcc taccaggcca tcccctcgct gcgtgaatac ctgctcgtcg
    10081 acccggacaa gcgctccgtg gagatctacc gcttcggcga cccggtgcgc tacgagacct
    10141 gcaccgaggg cgccttccgg ctcgactgcc tggatgtgga gatcacgctg gacgaggtgt
    10201 acgccgacgc cgaggcgccc tgaaacgcgc ctgcccggca ccgccccgcg ccccacggcc
    10261 gccctgggcc gagaacccgc aggcccggct cacaccccca ggtagcgccc ccacagctcg
    10321 cgtcgcgcgt ccagctcggc cgagctgccc tgccaggcga tgcggccgcg ctcgaggatg
    10381 aggttgtggt cggccagcgg cagcagcttg tcgacgtatt tgtccaccac cagcgtggtc
    10441 tgcccctgcg ccttgagcag cgcgaggcag cgccagatct cctcgcggat caccggggcg
    10501 aggccctcgg tggcctcgtc gaggatcagc aggcgcgggt tggtcgacag cgcgcgcgcg
    10561 atcgccagca tctgctgctc gccgccggag agctggttgc cgaggtggcc ggcgcgctcg
    10621 gccaggcgcg ggaagagcgc gtagagccgc gccggcgtcc atggctcggc gacgccgttg
    10681 cggcacgcgg cgaaggcgac caggtgttcg tgcaccgtga ggttggggaa gcactgtcgt
    10741 ccctcgggca cgatggccac gccgaggcgg gcgatggcgt cggcgcgctc ggcgtggatc
    10801 gggcggccgt cgaagacgat ctcgccgcgc tgcgggcgca ggccgccgac gatgctgcgg
    10861 atcgtggtgc tcttgcccat gccgttgcgc ccgagcagcg cgacgacctc gccggcgcgg
    10921 atgtcgaagt cgagtccgaa cagcacccgg ctggcgccat aaccggcctc gaggccccgg
    10981 cagcacagca gcggcgcgtt catgtcgcca cctcggtacc cagatacacc gcctgcacct
    11041 cggcgtgccc cttgacgtgg gcggcgtcgc ccgaggtcag caccttgccg tacaccagca
    11101 ccgagatgcg gtcggcgagc tggaagacgg catccatgtc gtgctcgatg agcaggatcg
    11161 cggtctcgct gcgcaggctg cggatcaggt ccaccatctg ctgcgaatcc tccggcccca
    11221 tgccggccat gggctcgtcg agcagcagca gcttgggccg tgcggcgagc gcgagcgcga
    11281 ggtcgagccg cttctgcagg ccgtggggca gcgtgccggc gttgcgctcg agcacctcgg
    11341 ccaggcccgc gcgctgcgcc agcgcctcgg cgcgttcctg caaggcatgc tcggcgtcgc
    11401 ggcgcgacag gcagcggaaa ctcgacccgg cctgcgcctg caccgcgagc agcaggttgt
    11461 cgcgcacgct gtcgttgcgg aacacgctgg tgatctggaa gcagcgcgcc aggccggcgc
    11521 gggtgcgcgc gtgcggcgcc agcgcggtca ggtcgacgcc gtcgaggacg atgcgcccgg
    11581 cgtccgccgg cagcaggccg gagatcaggt tgaccagagt ggacttgccg gcgccgttcg
    11641 ggccgatcag cgcatggatc tcgcccgcct cgacggcgag gtctacgtga tcggtggcga
    11701 gcaggccgcc gaagcgcttg accaggccct cggccctgaa caggctcatc gcacactctc
    11761 ccggccgccg cggcgctcga gcagcgccgc cacgccctgc ggcgcgtgga acaccaccag
    11821 cagcaggagc agcccgagcg gccagtgcca gtagtcggtg tacagcttga gcgcctcctc
    11881 cagcgtcagc cacagcgcca cgcccagcgg tgcgccccag cgccggccgg cgccgccgag
    11941 catcaccatc accagcagca gcgccgactg cgtccagtgc atgatcgacg ggctgacgaa
    12001 ggcgttgtgg ctggcgagca ggccaccggc cagccccgcg accgcgccgg cggcgacgaa
    12061 gccggcgagc ttgaggccat acaccgggta gccgagcgcc accatgcgcg tctcgttgtc
    12121 acggatgccg cgcagcgcgt ggccgtagcg cgagtgcgcg acgcggctga aaagcgcgaa
    12181 caccgccgcg gcgatcgcca gcaccaccca gtagaagacc tgcgcatgcg cgccatccag
    12241 ccaggcgccc aattccagcg gcgtgtagag gccgtagccg tcgtcgccac catatgtgcg
    12301 cagcgacacc gccaggtagt acagcatctg cgcgaaggcg agcgtgatca tgatgaagta
    12361 caccccgcgc gtgcgcagcg acaccgcgcc gatcgccgcc gcggccagcc cggcgaccag
    12421 cgccgcgctg ccccaggcca gccaggccga cgaaaacccg gcctcgacca gcgccaccac
    12481 ggtgtaggcg cccacgccga tgaagcccgc gtggccgagc gccgccatgc cgccgtagcc
    12541 gaggatgaag ttgaggctgg tcgcggcgat cgccacgatc agcacccggc gcacgaagcc
    12601 gacgtaatac tccagcccga gggccggcgc gagcagcggg aaagcggcca gcagggccag
    12661 caccagccag ggcaggcggc gcgcgaggcc gggaaaacgc gcgtgcgtga tcgccgccac
    12721 agcgcccggc gcggaggatg ggttctgcgg agtcgacccc tgcatcaccg ccctcacccg
    12781 cgcgcgggga acagccccgc gggtttcagc gtcagcaccg ctgccatcag cacgtacatg
    12841 gcgatgccgg ccagggccgg gccgagatcg gccgcgaccg agggcggcag caccgcgcgc
    12901 agcgcaggtg gcaggaaggc gcgcccggcg gtatcgacca tccccaccag cagcgcggcc
    12961 acgaaggcac cgcgcaccga gccgatgccg ccgatcacga tcaccaccag cgccgggatc
    13021 aggatcgcct cgcccatgcc gatctgcacc gcgctgatcg gcgccatcag cgccccggcc
    13081 agcgccgcga gcgccgcgcc gagcgcgaac acgaaggcga acaccccgcc cacgcgcacg
    13141 cccatgtgct ccgccatctg ccggttcgag gcgccggcgc gcaccagcat gccgacgcgg
    13201 gtcttgttca ccagcaggta gagcccgagc gccaccgcca gcccggcacc gatcagcagc
    13261 aggcggtagg acggataggg caggccctgg aagagatcga ccggcccggc cagcgccgcc
    13321 ggggtcgagg cgagcagcgg tgccacgccc cagatcgcct tcaccgcgtc gtcggcgatc
    13381 aggatgatgc cgaaggtggc gagcacctgg acgaggtggt cgcgccggta cagccggcgg
    13441 atgacgacga actccacgac cgccgcgatc gccaccgtca cccccaccgc gaccgccacc
    13501 gcaagcacga acgccccgct cgcctcatgc acgcgcgcgg cgacgtaggc gccagccatg
    13561 tagagcgagc cgtgggcgag gttcatggtg tccatgatgc cgaacacgag cgtgagcccg
    13621 gccgcgatca ggaacagcat gagcccgtag cccaggccgt tgagcagttg ctcgaagacg
    13681 aagatggcat ccatcggctt atccggagtt caggtccgcc gccgagcgcc cccctgcagg
    13741 agcgccggca ggcgcgaaag cggcggtgcc aatctgcacc cgcgtcgatc gcccacggag
    13801 cgtcttcacg gctgccgccg ctcctgcacg gggtcggccc ggcgttctca catcttgcac
    13861 gcacccacgt aggcgtcctg gtgcttctcc agcgtcgtgc cgaccagctt gttggtgatg
    13921 cggccctcgg cgtccttgcc gacctcgcgc aggtagtagt tctgcaccgg gaagttgttg
    13981 gcgccgtact ggaactcgcc gcgcagcgac ttgaagctcg ggttcttcag cgccttcagc
    14041 accgcctcgc ggtcctcgat cttgccgccg acgtcgcgca cggccgcgtc catcgccatc
    14101 agcgtgtcgt aggccatcgc tgcatacacc gacgggtagc gcccggcgta cttctggcgg
    14161 aaggcagcga cgaactcggt attcgcgggg ttctgcaggt cgtgcgtcca gtgcgcggtg
    14221 ttgagcacgc cgagcatcgg ctcgcccacc gcctggatca cgtcctcgtc ggccgagaag
    14281 ccgggggcga tcagcgggat gtccttgagc ccgccaccga cgaactgctt gacgaagttg
    14341 atccccatcg cgccgggcag gaagaagaac accgcgtccg gcttggcggc gcggatctgc
    14401 gcgatctcgg cggcgtagtc gatctggccg agcttggtgt agatctcgtc cttcacgccg
    14461 cccttgtaca gccgcttgaa gccgttgagg tgatccttgc ccgccgggta gttgggcgcg
    14521 atcagcacga cgttccggta gcccttctcg ttggcgacct tgccggcggc ctcgtcgtag
    14581 gtgtcgttct ggtactgcgc gaagaagtac gggttgcact tctcgccggc gtaggcgctc
    14641 gggcccgggt tggccgacag gtagggcacc ttggcggcga acagcgcggg gccgacggcg
    14701 agcgcggcgt tggagccgat cgggccggtg aagaagtgga tgccgtcgcg ctgcaggaag
    14761 cgggccacga gctgattggc ctgctcgggg ttgccgccaa agtcgttgcg gatgaactcc
    14821 gccggctggc cgccgagctt gccgccgagc ttctcgatcg ccagctcgaa gccgtcgcgc
    14881 gcctcggcgc cgagcgcgga gaacggcccg gagaggtcga gcgcgatgcc gaccttgatg
    14941 tcggcggcgt ggacattgag ggcggcagcg ccgtacaggg cgagcgcgac ggacagcttc
    15001 ttcatctgca gcatgggggt ctcctcgatt ggtctctttg ccgcccgcag cgccggcgcg
    15061 cgagcgccgc gccgcgcgcg aaggccgccg attctacccc agcccggccg cgactcgcgc
    15121 cgcccgtcgg cgccgctgct gtatgaaacc gcaggccgca tgcgtgcggc ctgatagact
    15181 tgcacatccg catttcccac gcatccccgc cccatgatcg gacgcatcac cggcaccctg
    15241 ctggaaaaga acccgccgca gatcctcgtc gacgtgcacg gcgtcggcta cgagatcgac
    15301 gtgccgatga gcaccttcta caacctgccc gccaccggcg gcgcggtgag cctgcacacg
    15361 cacttcgtgg tgcgcgagga cggccacttc ctgttcggct tcgccaccga cgaggagcgc
    15421 gtcaccttcc gccagctgct caaggtgtcg ggcgtgggcg cgcgcatggc gctggcggtg
    15481 ctgtccggcc tgtcggtcaa tgacctcgcc caggcggtgg cgctgcagga ggcggggcgg
    15541 ctggtgaaga tccccggcat cggcaagaag accgccgagc gcctgcttct cgagctgcgc
    15601 gacaagctcg gcaagggact gcccagcatg acgggcgtgc gcctggccgc ggcgcccggc
    15661 gcagcgccgg acgcgaagag cgacatcctc aacgcgctgc tcgcgctcgg ctacaacgag
    15721 cgcgaggcgc tcgcggcgat gaagggcctg gcggaggacg tcggcgtgtc ggacggcatc
    15781 cgccaggcct tgaaggcgct gtcgaagggc tgaacggagg ctgaggcgca gacatgatcg
    15841 aaaccgacaa gctcaaggcc gccgcccccg ccgagcgcct gatctccgca gccccggccg
    15901 accgccagga ggacgcgatc gagcgcgcgc tgcgccccaa gcgcctcgcc gaatacgtcg
    15961 gccaggccaa gatccgcgag cagctcgaga tcttcatcca ggctgcgcgc aagcgcagcg
    16021 aggcgctcga ccacgtgctg ctgttcggcc cgcccgggct gggcaagacc acgctcgcgc
    16081 acatcgtcgc cgccgagatg ggggtgaacc tgcgccagac ttcgggcccg gtgctcgagc
    16141 gcgccggcga cctcgccgcg ctgctcacca acctcgagcc gcacgacgta ctcttcatcg
    16201 acgagatcca ccgcctgtcg ccggtggtgg aggagatcct ctacccggcc ctggaggatt
    16261 tccagatcga catcatgatc ggcgaagggc cggcggcgcg ctcggtcaag ctcgatctgc
    16321 cgccgttcac gctggtcggc gccaccaccc gcgccggcat gctgaccaac ccgctgcgcg
    16381 accgcttcgg gatcgtgtcg cggctggagt tctacaccgc ggacgagctc gccttcatcg
    16441 tcgggcgctc ggcgcgcctg ctcaacgtcg agatcgacga cgccggcgcg ctcgagatcg
    16501 cccgccgcgc gcgcggcacg ccgcgcatcg ccaaccgcct gctgcgccgg gtgcgcgact
    16561 acgccgaggt caaggccggc ggccgcatca ccgccgaggt ggccgacgcg gcgctgcgca
    16621 tgctggacgt cgacaacctc ggcctcgacc tgatggaccg caagctgctg tcggcaatgc
    16681 tggagaagtt cggcggcggc ccggtcggcc tcgacaacat cgcggcggcg atcggcgaat
    16741 ccaccgacac catcgaggac gtgatcgaac cctacctgat ccagcagggc tacctgcagc
    16801 gcacgccgcg cgggcgcatg gcgacgcatt cgatctggca gcacttcggg ctggcgccgc
    16861 cgcgcgtcgg cggcgacctc ttccagtagg ccacggggcc ggcgatgcgc tcgctgcagg
    16921 tggtgatgct gatgctgtgc gtgctgggcg ggctgttcct gctcgtgcgc gcgcccgagt
    16981 tcttcctgcc tgcgcagtgg gacccctcga tcgggcgcag cttcgatccg ctcgcctcgc
    17041 gcctgctcgg cgccgggctg ctggcgctcg ccgcggccgg cgcgggctac atccatgcga
    17101 tgtattacac gatgccgcgc cggctgcccg gcccggcggc gcaacgtcgc catttcgccc
    17161 tgctgctcgc cgccctggtg ctgatcggcg cggcgctggc gcgcgccgag ccgggtccga
    17221 atcc
//
LOCUS       DAOTIN010000066        17198 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_4010_length_17198_cov_9.376247, whole genome shotgun sequence.
ACCESSION   DAOTIN010000066 DAOTIN010000000
VERSION     DAOTIN010000066.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 17198)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 17198)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17198
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4010_length_17198_cov_9.376247"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..458)
                     /locus_tag="P5537_10765"
     CDS             complement(<1..458)
                     /locus_tag="P5537_10765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding protein"
                     /protein_id="HRV78565.1"
                     /translation="MNRRNFVKALTLSASIAAIGLPAGAHAADTIKVGILHSLSGTMA
                     ISETALKNVALMTIEEINAGGGVLGRKLEPVVVDPASNWPLFAERARQLLAQDKVAAV
                     FGCWTSVSRKSVLPVFKELNGLLFYPVQYEGEELEKNVFYTGAAPNQQAIP"
     gene            complement(797..1642)
                     /locus_tag="P5537_10770"
     CDS             complement(797..1642)
                     /locus_tag="P5537_10770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HRV78566.1"
                     /translation="MRTHPFGADGPALRVVGQGTWYLDEARRADAVAALRAGLDHGLA
                     HIDTAEMYGDGAAEELVGEAIAGRRDEVFLVSKVLPHNASRRGTIAACERSLKRLRTD
                     RLDAYLLHWPGDHALEDTFAAFDELQRAGKILHWGVSNFDVPDLDEALAIAGPGRIAC
                     NQVLYHLQERAVEHAVLPWCERHGVALVAYSPFGHDAFPAPDTTGGRVLADIAAARGA
                     SPRQVALAFLTRRPSVLAIPKAARAAHALDNAGAPALELSAAEIERIDAAFPRGAKPR
                     WLPML"
     gene            complement(1711..2463)
                     /locus_tag="P5537_10775"
     CDS             complement(1711..2463)
                     /locus_tag="P5537_10775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HRV78567.1"
                     /translation="MILADGIRKRFGANEVLKGVSLTLARGEVVAVIGPSGSGKSTFL
                     RCLNHLETIDAGRIVIEGDTLADNDAGGHARYVADAEVRRICARMGMVFQHFNLFPHL
                     TVLQNVIEAPITVKGMKREAILPKAEELLRKVGLFDKRDAYPSRLSGGQKQRVAIARA
                     LAMEPDIMLFDEPTSALDPELTGEVLRTMRQLADEHMTMLVVTHEMGFAREVASRVVF
                     MDGGELIESRPAAEFFANPQHPRTRAFLDSML"
     gene            complement(2498..3148)
                     /locus_tag="P5537_10780"
     CDS             complement(2498..3148)
                     /locus_tag="P5537_10780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HRV78568.1"
                     /translation="MDYILSILGPLAEGSLVTLQLFLITLLLAVPLGLGLALVRISRF
                     RVASQAVNGYIWLMRGTPLMLQMLFIYYALPFVPGVGIRLPDFPAAIVAFALNYAAYF
                     AEIFRAGIQSIDRGQYEGAKVLGFSYGQTMRRIVLPQVIKRILPPMSNETITLIKDTS
                     LIYVLALNDLLRAARGIVQRDFTITPFIVAAGFYLIMTLVLTWLFQRLEKRHAVYD"
     gene            complement(3276..4073)
                     /locus_tag="P5537_10785"
     CDS             complement(3276..4073)
                     /locus_tag="P5537_10785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004330253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HRV78569.1"
                     /translation="MKLSSLLMLSLTAGALLAGCGKNETAPAAQSAAAPAAPAKIVIG
                     LDDNFPPMGFRNEKNELVGFDIDLAKEAAKRLGIEVEFKPIDWSAKEAELNGKRVDAL
                     WNGLTITEERRKNIGFTSAYMENHQIIVVPAASTIKTKAELAGKIIGIQDGSSAVDAV
                     QKDPVAASFKELKKFGDNVTALMDLTTGRLDAVVLDEVVGRYYTAKKPNDYAVLDDHF
                     GTEEYGVGTRKDDTALLAKLQQAMDAMKADGSAARISTEWFGKNIIK"
     gene            complement(4214..5080)
                     /locus_tag="P5537_10790"
     CDS             complement(4214..5080)
                     /locus_tag="P5537_10790"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="YXWGXW repeat-containing protein"
                     /protein_id="HRV78570.1"
                     /translation="MTIRSPLSPMLLAAALALGGCAVVPADDYGYYDDDRYYDRETVI
                     VTPPPRIEYRGLPPAAGYVWIDGYWNRVGPRPHWVPGYWSPPRVHPRPIVQPRPHIGT
                     RPDWRPDRRDEHDHRRWRDDDRRGDDKRWSGRDDGTRREGERWRERDGDPRTWPGFTP
                     RRDPRGDRDGMRDRRDPREDARPPRIVQERPPGAREGLLHAEPPRQRIERPAFGAPGG
                     ARPELRPAGAGGEVRSPRPREAGGRSPETFQGFRRDGDGEARRSFRRDAREDGARPEA
                     RGREPAGNRTAN"
     gene            complement(5247..6308)
                     /gene="hypE"
                     /locus_tag="P5537_10795"
     CDS             complement(5247..6308)
                     /gene="hypE"
                     /locus_tag="P5537_10795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004381982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase expression/formation protein HypE"
                     /protein_id="HRV78571.1"
                     /translation="MNTVKPAYVRPLDLSKGHVDLGFGAGGRAMAQLISELFMRAFAN
                     DFLARGDDGAVLPAPAAGERLVMATDAHVVSPLSYPGGDIGSLSVHGTVNDLAVMGAR
                     PLYLAASFILEEGYALAELARIVDSMAAAARAAGVAVVTGDTKVVEQGKGDGVFITTT
                     GVGALPAGRDPGGARARSGDVVLLSGRIGDHGMAIMAQRESLAFDSEIVSDSAPIHGL
                     VEALYAAVPAEAIRVLRDPTRGGLATTLNEIATQSGVGMELDEVAIPVSPQVHAACEL
                     LGLDPLYVANEGKLVVLCAPEHAGAALAALRAHPLGAEAARIGCATADPQHFVQLRTA
                     LGGRRMVDWIAGEQLPRIC"
     gene            complement(6305..7480)
                     /gene="hypD"
                     /locus_tag="P5537_10800"
     CDS             complement(6305..7480)
                     /gene="hypD"
                     /locus_tag="P5537_10800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011767525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016530 - metallochaperone activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase formation protein HypD"
                     /protein_id="HRV78572.1"
                     /translation="MKYVDEFRDGTLAAGLARAIAREADRGRDYAFMEFCGGHTHAIS
                     RYGVSDLLPANVRMIHGPGCPVCVLPIGRVDMAIRLALARPEVILCTYGDCLRVPASD
                     GLSLLKAKARGADVRMVYSAADALALAAREPAREVVFFAIGFETTTPPTALVLREAAA
                     RGLANFSVICNHVLTPPAITAILDSPAAGELGTLHLDGFIGPAHVSTLIGSRPYEAFA
                     ARYRKPVVIAGFEPLDVMQAIRMLVRQVNTGRAEVENEFTRAVVRDGNPKAQAIVSEV
                     LELRDEFEWRGLGVLARSALRIRPAFAPWDAEAKFGLDYRPVPDHRACECGAILRGVK
                     KPADCKLFGTVCTPETPMGSCMVSSEGACAAHYNYGRFRDLPAVAADKPVTQAQESA"
     gene            complement(7477..7710)
                     /locus_tag="P5537_10805"
     CDS             complement(7477..7710)
                     /locus_tag="P5537_10805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HypC/HybG/HupF family hydrogenase formation
                     chaperone"
                     /protein_id="HRV78573.1"
                     /translation="MCLAIPARIVELLDGDQCRVELGGVRKEISLALVDGAAVGDYVI
                     VHVGYALTKLDAEEAAQTLALIAEAGIAPEAGR"
     gene            complement(7713..8960)
                     /locus_tag="P5537_10810"
     CDS             complement(7713..8960)
                     /locus_tag="P5537_10810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyltransferase HypF"
                     /protein_id="HRV78574.1"
                     /translation="MSVATFPDADMEASRPPMPAEAASAPIGESLSLPPVGTRRLAEA
                     PPILALGAWFKHAACLLEDGRAQFGPNLGDLDNADACRAVEPAALALLAQAAAPVRAI
                     AHDLHPDFHSTRVACALAARLDVPAIGVQHHHAHVGAVLAEHGRFDARPVLGLALDGV
                     GLGTDGEAWGGELLWVAGGECVRLGHLRPLRLPGGDRAAREPWRMAAAVLHASGRGDE
                     IARRFARQPAAAMLAQVLARPALCPPTSSLGRHFDAAAGLLGLCEVMQNEAEAAIALE
                     RLAASTAAPAVDRGDWRILTDAAGTVAPALPRLELDLHPLLLCLADEPDAARGAACFQ
                     ATLAAALVDWIEAARRLTGGATVVLSGGCLHNRLLADALHSALPAQGFEVLGAHRLSP
                     GDAGLALGQAWVALHQLASIKEN"
     gene            complement(8957..9916)
                     /gene="hypB"
                     /locus_tag="P5537_10815"
     CDS             complement(8957..9916)
                     /gene="hypB"
                     /locus_tag="P5537_10815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016530 - metallochaperone activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase nickel incorporation protein HypB"
                     /protein_id="HRV78575.1"
                     /translation="MCTTCGCGSGETRIGALGGGRPAPAVHPHPGATRAWRAVGEHAP
                     TPPTPPARPAPARPASMPPGAVPDTVPGHHHLDFGSGPAHAHAPGLSQAQMLRIERDI
                     LGKNDARAAENRAWLATRGIFALNLVSSPGSGKTSLLVRTLQLLGGRVPAAVIEGDQQ
                     TEFDAERIRATGVPALQINTGKGCHLDADMVARALPRMELAEDSLLLIENVGNLVCPA
                     AFDLGEAHKVAILSVTEGEDKPLKYPDMFAAADLMLLNKVDLLPYLAFDAGRAIDFAL
                     RVNPRLRVLRTSATTGEGLDEWIAWIEAGLATARAGRAAGVRA"
     gene            complement(9980..10321)
                     /gene="hypA"
                     /locus_tag="P5537_10820"
     CDS             complement(9980..10321)
                     /gene="hypA"
                     /locus_tag="P5537_10820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004307733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008901 - ferredoxin hydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="HRV78576.1"
                     /translation="MHEMSLAEGVRAIIEEAAQADRFRHVRTVVLEIGELAAVEVDAL
                     RFCLGAVLADTVAAGAAIEIETLPGAGWCPDCAQTVPIHQLYDACGRCGGYRVQASAG
                     REMRVKALEVD"
     gene            10578..11600
                     /locus_tag="P5537_10825"
     CDS             10578..11600
                     /locus_tag="P5537_10825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004372891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="META domain-containing protein"
                     /protein_id="HRV78577.1"
                     /translation="MKASSLLGLTFLAALAGGCGLLGRAAPAASVEATTAAPVQRPSA
                     PALALDPQPPIEFRCGERRVELRHFGELATLGVDGKVFTLRPERSASGMRMVSVDDAR
                     TGIWVKGNSALLSLAGVEQPECLRVAEKPLFRAVGNEPAWRLDIGAQGLELIADDGAS
                     RAFASAPLIVEAEGLRSYQGTSAGGELEALVFERVCVDTMSGMTHPNTVEVRWQERVL
                     RGCGGDPALLLQGEPWEVVELDGSAVTDPARITLGFAAGGRLAGGAGCNRYFGSYALS
                     GEGLRLSPRGATQMACAPRAMEDERRFMAAAASVSGFAITTDGRLELRAGERVVMRAR
                     RASGPR"
     gene            complement(11958..12458)
                     /gene="nusB"
                     /locus_tag="P5537_10830"
     CDS             complement(11958..12458)
                     /gene="nusB"
                     /locus_tag="P5537_10830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004372893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HRV78578.1"
                     /translation="MSDIDNTQAEGGTGAPNPTSKMARRRARELALQGVYQWLLSGNT
                     ATTVQRHLESETENLDKIDRELFVSLLRGATGAADELRGCFEPLLSRPVAELSPIEHA
                     ILLLGTHELRHNLDTPYRVVINEAIELAKGYGGTDGHKFVNGVLDKLAARLRPEEVEA
                     ARAKRG"
     gene            complement(12455..12958)
                     /gene="ribH"
                     /locus_tag="P5537_10835"
     CDS             complement(12455..12958)
                     /gene="ribH"
                     /locus_tag="P5537_10835"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HRV78579.1"
                     /translation="MQRNQSENARQGARYDGIDEIEPSFAGAGVRVGIVMARFNLDIC
                     EGLLSACTDELLALGVARADIRIVTVPGALEIPLVLQTMARSGRHDALVALGAVIRGE
                     TYHFELVSNEMGAGVTRVGLDTGLPIANGVLTTEDDDQAVARMREKGADCARAAVEMA
                     NLLKVVR"
     gene            complement(12976..14067)
                     /gene="ribBA"
                     /locus_tag="P5537_10840"
     CDS             complement(12976..14067)
                     /gene="ribBA"
                     /locus_tag="P5537_10840"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004307725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HRV78580.1"
                     /translation="MSALAPITDIIADIKAGRMVILVDEEDRENEGDLVMAAEFVTPE
                     AINFMAKHGRGLICLTLTDERCRQLGLQQMVRDNRTPHGTAFTVSIEAATGVTTGISA
                     HDRARTVQVAVARNARPDDIVTPGHIFPLTAQKGGVLIRAGHTEAGCDLAQLAGLEPA
                     SVICEILKDDGTMARLPDLVEFGQAHGLKIGAIRDLIEYRAANDHLVEKVAEKDVDTP
                     HGRFRLTAFEDKTSGDVHFALSHGDIRPERETLVRVHEPISVLDFLDAGSGHHTFPVN
                     QALATLAAAEAGVIVLLYRPMSGRELLAGLNGGHDRPTAKWDARLFGVGAQILRALRV
                     GKMRLLASPRKIPSMTGFGLEITGFVDKN"
     gene            complement(14102..14710)
                     /locus_tag="P5537_10845"
     CDS             complement(14102..14710)
                     /locus_tag="P5537_10845"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004307724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HRV78581.1"
                     /translation="MFSGIVAAVGRIEHVEALADGVRITVDTNGLDLSDVIVGDSVAH
                     SGVCLTVVEMDGPRLRYDVSRETLNCTVGLDTVGGEVNLEKSLRLADRLGGHLVTGHV
                     DGVGEVVKFAPVGESHELVIRAPAAIAGYIARKGSVTVNGVSLTVNRVEGRDFWINLI
                     PHTVAVTNLKHLAPGSKVNLEIDLIARYVERMLEWKNDAAQA"
     gene            complement(14769..16616)
                     /gene="dsbD"
                     /locus_tag="P5537_10850"
     CDS             complement(14769..16616)
                     /gene="dsbD"
                     /locus_tag="P5537_10850"
                     /EC_number="1.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004307722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047134 - protein-disulfide reductase
                     (NAD(P)) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide reductase DsbD"
                     /protein_id="HRV78582.1"
                     /translation="MHRLFLLLALIASLLLPTAARANPIEPEKAFAMRAQALDAQTIE
                     VVFEIAKDYYLYGDKFRFEAEPAAVGFGALEKPAGKMKKDDFFGEVETHRGELRILVP
                     VQAPPGTTRFELFATSQGCWDGGICYPPTTQQASIDLTAPPKKAGGFLDSVLGGRAGA
                     GGASSAPVALAATADGAGSPAADAVSSDETGDIARLLSGASVPIILLSFFGFGLLLAF
                     TPCTFPMIPILSGIIVGQGNKVSHMRAFVLSLAYVLGMAATYALAGVAAGMTGTMLSA
                     ALQNVWVLSAFALLFVLLSLSMFGFYELQLPSALQSRLADTASHGKGGHLGGVTLMGV
                     LSALIVGPCVAAPLAGALLYIAQTGDAVLGGWALFAMGLGMGAPLLAVGVASRSLLPK
                     VGPWMEGVKKAFGVMLLAVALWMITPVIPALAMMLGWAALLLFSAIFLHAIDPLPPQA
                     KGWQRFWKGVGVVLLLAGAAILVGALAGSRDPLQPLSVLRAQAAAAVNLPQFEKVDSI
                     AALDARLAQTDRPVLLDFYADWCVSCKEMERFTFSDAAVAERMGRMLLLKADVTANTD
                     EHKALLKRFGLFGPPGIIFFDGRGKEREGMRVVGFMKAEPFATVLDRAL"
     gene            complement(16759..17115)
                     /gene="cutA"
                     /locus_tag="P5537_10855"
     CDS             complement(16759..17115)
                     /gene="cutA"
                     /locus_tag="P5537_10855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0010038 - response to metal ion [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="divalent-cation tolerance protein CutA"
                     /protein_id="HRV78583.1"
                     /translation="MPASPAATTDAPRALLVFTSLPDAASAETLASALIGRRLAACVN
                     ILAPCTSIYRWQGATETATEVPVLIKTTPARYAALEAAIRARHPYELPEIVAVPVMQG
                     LPGYLDWVEFETTGDD"
BASE COUNT         2339 a         5742 c         6600 g         2517 t
ORIGIN      
        1 gggatcgcct gctggttggg cgcggcgccg gtgtagaaga cgttcttctc cagctcctcg
       61 ccctcgtact gcaccgggta gaagagcagg ccgttgagct ccttgaacac cggcagcacc
      121 gacttgcgcg acaccgaggt ccagcagccg aacaccgccg ccaccttgtc ctgcgccagc
      181 agctggcgcg cgcgctcggc gaacagcggc cagttcgagg ccgggtcgac caccaccggc
      241 tcgagcttcc tgccgagcac gccgccgcca gcgttgatct cctcgatggt catcagcgcc
      301 acgttcttca acgcggtctc ggagatcgcc atcgtgcccg acagcgaatg caggatgccg
      361 accttgatgg tgtcggcggc gtgcgccccg gcgggcaggc cgatcgcggc gatggaagcc
      421 gaaagcgtga gggctttgac gaagttgcga cggttcatgg acgggcctct tgcagtggat
      481 ggaagtcgag cgcagcgcag gctgcgtcga ctacccctct gcaagcggcg tgccacatgg
      541 ccggcgaagc gccggatggg gtgtgggaag aggccggaat ccgcgccgtt gatgcgctcg
      601 cggcgcgcgg acggattgcg tgccggcccg cctgccgtcc cgtcggtgcg ccttcctcgc
      661 ggatgtcgcg ccctgtggcg atgcagcacc ccggaggcgt gccccatcgc agtgcagcaa
      721 tcccctggcc gccggtgcgc atcagccgcg ccgcgccacc ccgctcctca cgccttacgc
      781 ctcccgcctc acgccctcac aacatcggca gccagcgcgg cttcgcgccg cgtgggaagg
      841 ccgcgtcgat gcgctcgatc tccgcggcgg acagctccag cgcgggcgcg ccggcgttgt
      901 cgagcgcatg cgccgcgcgg gcggccttgg ggatggccag cacggaaggc ctgcgggtga
      961 ggaaggcgag cgcgacctgg cgcgggctgg cgccgcgggc ggcggcgatg tcggcgagca
     1021 cgcgaccgcc cgtggtgtcg ggcgccggga aggcgtcgtg gccgaagggg ctgtaggcga
     1081 ccagagcgac accgtggcgc tcgcaccagg gcagcacggc gtgctccacc gcgcgctcct
     1141 gcaggtggta gagcacctgg ttgcaggcga tgcggcccgg gccggcgatg gcgagcgcct
     1201 cgtcgaggtc gggcacgtcg aaattgctca cgccccagtg caggatcttg ccggcgcgct
     1261 ggagttcgtc gaaggcggcg aaggtgtctt cgagcgcgtg atcgcccggc cagtgcagca
     1321 ggtaggcgtc gaggcggtcg gtgcgaaggc gcttcagcga acgctcgcag gcggcgatcg
     1381 tgccgcgtcg gctggcgttg tgcggcagca ccttggagac gaggaagacc tcgtcgcggc
     1441 ggccggcgat ggcttcgccg acgagctcct cggcggcgcc gtcgccgtac atctcggcgg
     1501 tgtcgatgtg ggccaggccg tggtcgaggc cggcgcgcag cgcggcgacc gcgtcggcgc
     1561 ggcgggcctc gtcgaggtac caggtgccct ggccgaccac gcggagcgcg gggccgtcgg
     1621 cgccgaaggg atgggtgcgc atggggaagg ctccttggcg gggagaatga gaccgccgcc
     1681 gagaatagcg cttcccgggt gcgccgagcc ctacagcatg ctgtcgagga aggcccgcgt
     1741 gcgtggatgc tgcgggttgg cgaagaactc cgccgccggg cgcgactcga tcagctcgcc
     1801 gccgtccatg aacaccaccc ggctggcgac ctcgcgcgcg aagcccatct cgtgcgtcac
     1861 caccagcatg gtcatgtgct cgtcggcgag ctggcgcatg gtacgcagca cctcgccggt
     1921 gagctcgggg tcgagcgccg aggtgggctc gtcgaagagc atgatgtcgg gctccatcgc
     1981 cagcgcgcgc gcgatcgcca cgcgctgctt ctgtccgccc gagagcctcg aggggtaggc
     2041 gtcgcgcttg tcgaagaggc cgaccttgcg cagcagctcc tcggccttgg gcaggatggc
     2101 ctcgcgcttc atgcccttca ccgtgatcgg cgcctcgatc acgttctgca gcacggtgag
     2161 gtgcgggaac aggttgaagt gctggaacac catgcccatg cgcgcgcaga tgcggcgcac
     2221 ctcggcgtcg gcgacgtagc gcgcgtggcc gccggcgtcg ttgtcggcga gggtgtcgcc
     2281 ctcgatgacg atgcggccgg cgtcgatggt ttccagatgg ttgaggcagc gcaggaaggt
     2341 gctcttgccc gacccggagg ggccgatcac cgccaccacc tcgcccctgg ccagcgtcag
     2401 cgacacgccc ttcagcacct cgttggcgcc gaagcgcttg cggatgccgt cggcgaggat
     2461 catcggattc gtcatcggac ccgtcctcac ggcggcctca gtcatagacg gcatggcgtt
     2521 tctccaggcg ctggaagagc caggtcagca ccagcgtcat gatcaggtag aagccggcgg
     2581 cgacgatgaa cggggtgatg gtgaagtcgc gctgcacgat gccgcgtgcc gcgcgcagca
     2641 ggtcgttgag cgcgagcacg tagatcagcg aggtgtcctt gatcagggtg atggtctcgt
     2701 tgctcatcgg cggcaggatg cgcttgatga cctgcggcag cacgatgcgg cgcatggtct
     2761 ggccgtagct gaagccgagc accttggcgc cctcgtactg gccgcggtcg atggactgga
     2821 tgccggcgcg gaagatctcg gcgaagtagg ccgcgtagtt gagcgcgaac gccacgatcg
     2881 ctgccgggaa gtcgggcagg cggatgccga cccccggcac gaagggcagc gcgtagtaga
     2941 tgaacagcat ctgcagcatc agcggcgtgc cgcgcatcag ccagatgtag ccgttgaccg
     3001 cctggctggc gacgcggaag cgcgagatgc gcaccagcgc cagcccgagc ccgagcggca
     3061 ccgccagcag cagggtgatg aggaagagct gcagcgtgac cagcgagccc tcggcgagcg
     3121 ggccgaggat gctgaggatg tagtccatgg cgggacgccg ggcgagcggc gggcaggtgg
     3181 gggagggcgg tggtgtcgac gcgggcgacg cccgaaccgg cgcacgcagg ggagcaaaac
     3241 ggttcgcagc ggccgccgcg aacccccggg cctgcttact tgatgatgtt cttgccgaac
     3301 cactcggtcg agatgcgcgc tgcgctgccg tcggccttca tcgcgtccat cgcctgctgc
     3361 agcttggcga gcagcgcggt gtcgtccttg cgggtgccga cgccgtactc ctcggtgccg
     3421 aagtggtcgt cgagcaccgc gtagtcgttc ggcttcttgg cggtgtagta gcggcccacg
     3481 acctcgtcga gcacgaccgc gtccagccgc ccggtggtca ggtccatcag cgcggtgacg
     3541 ttgtcgccga acttcttcag ctccttgaag gaggcggcca ccgggtcctt ctgcaccgcg
     3601 tcgaccgcgc tgctgccgtc ctggatgccg atgatcttgc cggcgagctc ggccttggtc
     3661 ttgatcgtcg aggcggcggg caccacgatg atctggtggt tctccatgta ggcgctggtg
     3721 aagccgatgt tcttgcggcg ttcctcggtg atggtgaggc cgttccacag cgcgtcgacg
     3781 cgcttgccgt tgagctcggc ttccttggcg ctccagtcga tcggcttgaa ctcgacctcg
     3841 atgccgaggc gcttggccgc ttccttcgcg aggtcgatgt cgaagccgac gagttcgttc
     3901 ttctcgttgc ggaagcccat cggcgggaag ttgtcgtcga ggccgatgac gatcttcgcc
     3961 ggggccgcgg gggcggcagc ggattgggcg gcaggcgcgg tttcgttctt gccgcagccg
     4021 gcgagcagcg cgccggcggt gagggagagc atcagcagcg aggagagttt catcttggtc
     4081 ttgcccgtga ggggggtcgg ggacgggccg ggtgggcccg ccacggggac ggcgccggga
     4141 tgccggcgcc aaaaccatga ttctcgctgc actgcgtcag gcgagcaacc ttgccgctgc
     4201 ccgcggggag cgctcagttg gccgtccggt tgcccgcggg ctcgcgtccg cgcgcctcgg
     4261 gacgagcacc gtcctccctc gcgtcgcgcc ggaagctgcg tcgggcctcc ccgtcgccgt
     4321 cgcgccgaaa gccctggaag gtctcgggag atcgcccgcc cgcctcgcgg gggcgggggc
     4381 tgcggacttc gcccccggcg ccggcaggac gcagctcggg tcgcgcgccg cccggcgccc
     4441 cgaaggccgg acgctcgatg cgctggcggg gcggctcggc atggagcagg ccttcacgcg
     4501 cgccgggcgg gcgttcctgg acgatccggg gcggacgtgc gtcctcgcgc gggtcacgac
     4561 gatcgcgcat gccgtcgcga tcgcccctgg ggtcgcgtct cggggtgaag ccgggccagg
     4621 tgcgcgggtc gccatcgcgc tcacgccagc gctcgccctc gcgccgggtg ccgtcgtcgc
     4681 ggccgctcca gcgcttgtcg tcgccgcgcc ggtcgtcgtc gcgccagcgc ctgtggtcgt
     4741 gctcgtcgcg acgatcgggg cgccagtcgg gacgggtgcc gatgtgcggc cgaggctgca
     4801 cgatggggcg cgggtgcacc cgcggtgggc tccagtagcc gggcacccag tgcgggcgcg
     4861 gacccacgcg gttccagtag ccgtcgatcc agacgtagcc ggcggctggc ggcagaccac
     4921 ggtattcgat gcgcggcggc ggcgtgacga tcaccgtctc gcgatcgtag tagcgatcat
     4981 cgtcgtagta gccgtagtcg tcggcgggaa ccaccgcgca gccaccgagt gccagcgcgg
     5041 ctgcgagcag catgggcgag aggggcgagc ggatggtcat ggtttcgtcc tgccgcggtg
     5101 aaggatgcga catgcggagc ggttgggggc gggggcgctg ccgcccgcca cccccttccg
     5161 cgtctctgct gtctccacgc gcacgatagg cgatagcgcg tgcgtcgggt gggcggcgag
     5221 gtaatcagtt gtgacggcgc gatctctcag cagatccgcg gcagctgctc gccggcaatc
     5281 cagtccacca tgcgccgccc gcccagggct gtgcgcagct gcacgaagtg ctgcgggtcg
     5341 gcggtggcgc agccgatgcg cgccgcctcg gcgccgagcg gatgcgcgcg cagcgccgcc
     5401 agcgcggctc cggcgtgctc cggcgcgcac agcacgacca gcttgccctc gttggcgacg
     5461 tagagcgggt cgagcccgag caactcgcag gctgcgtgca cctgcggcga caccgggatc
     5521 gccacctcgt cgagctccat gcccacgccc gactgcgtgg cgatctcgtt cagcgtggtc
     5581 gccagcccgc cgcgggtggg gtcgcgcagc acacggatcg cctccgccgg caccgcggcg
     5641 tagagcgcct cgaccagacc gtggatcggt gcgctgtccg agacgatctc ggagtcgaag
     5701 gcgagcgatt cgcgctgcgc catgatcgcc atgccgtggt cgccgatgcg cccggacagc
     5761 agcaccacgt cgcccgaccg cgcgcgcgcg ccgccggggt cgcgcccggc cggcagcgcg
     5821 ccgacaccgg tggtggtgat gaagacgccg tcgcccttgc cctgctcgac caccttggtg
     5881 tcgccggtca ccaccgcgac gccggccgcg cgtgcggcgg cggccatcga gtcgacgatg
     5941 cgggcgagct cggcgagcgc atagccctct tccaggatga agctggcggc caggtagagc
     6001 gggcgcgcgc ccatcaccgc gaggtcattc accgtgccgt gcaccgacag gctgccgatg
     6061 tcgccgccgg gataagacag cgggctcacg acgtgggcgt cggtcgccat gaccaggcgc
     6121 tcgcctgccg ccggcgcggg cagcaccgcg ccgtcgtcgc cgcgcgcgag gaagtcgttg
     6181 gcgaacgcgc gcatgaaaag ttcggagatc aattgcgcca tcgcccgccc gccggcgccg
     6241 aagccgaggt cgacatggcc cttgctcagg tccagggggc ggacgtaggc gggtttgacg
     6301 gtgttcatgc ggactcctgg gcctgggtta cgggcttgtc ggcggcaact gccggaaggt
     6361 cgcggaagcg cccgtagttg tagtgtgcgg cgcaggcgcc ctcggaggac accatgcacg
     6421 agcccatcgg cgtctccggg gtgcacacgg tgccgaagag cttgcagtcg gcgggtttct
     6481 tcacgccgcg caggatggcg ccgcattcgc aggcgcggtg gtcgggcacc gggcggtagt
     6541 cgaggccgaa cttcgcttcg gcgtcccagg gtgcgaaggc gggacggatg cgcagcgccg
     6601 agcgcgccag cacgccgagg ccgcgccact cgaactcgtc gcgcaactcg agcacctcgg
     6661 acacgatcgc ttgcgccttc gggttgccgt cgcgcaccac cgcgcgggtg aactcgttct
     6721 cgacctcggc acggccggtg ttgacctggc gcaccagcat gcggatcgcc tgcatcacgt
     6781 cgagcggctc gaagccggcg atgaccaccg gcttgcggta gcgggcggcg aaggcttcgt
     6841 agggccggct gccgatgagc gtggagacgt gggcggggcc gatgaagccg tccaggtgca
     6901 gcgtgccgag ctcgccggcc gcgggcgagt cgaggattgc ggtgatcgcc ggcggggtca
     6961 gcacgtggtt gcagatcacg ctgaagttcg ccagcccgcg cgccgcggcc tcgcgcagca
     7021 cgagcgcggt ggggggcgtg gtggtctcga agccgatggc gaagaacacc acctcgcgcg
     7081 ccggctcgcg cgcggcgagc gcgagcgcgt cggccgcgga atacaccatg cgcacgtcgg
     7141 cgccgcgcgc cttggccttc agcagcgaca ggccgtcgga ggcgggcacg cgcaggcagt
     7201 cgccgtaggt gcacaggatc acctcggggc gcgccagcgc gagccggatc gccatgtcca
     7261 cgcggccgat cggcagcacg cacaccggac agcccgggcc gtggatcatg cgcacgttgg
     7321 ccggcagcag gtcggagacg ccgtagcgcg agatggcgtg ggtgtggccg ccgcagaact
     7381 ccatgaaggc gtagtcgcgg ccgcggtcgg cctcgcgcgc gatcgcccgc gccagcccgg
     7441 cggcgagcgt gccgtcgcgg aattcgtcca cgtatttcat cgcccggcct cgggggcgat
     7501 gccggcttcc gcgatcaagg ccagggtctg cgccgcctcc tccgcgtcga gtttcgttag
     7561 cgcgtagccg acgtgcacga tcacgtagtc gccgacggcg gcgccgtcga cgagggcgag
     7621 cgagatttcc ttgcgcacgc cgccgagctc gacgcggcat tggtcgccgt cgagcagttc
     7681 gacgatacgg gcagggatgg cgaggcacat gttcagtttt ccttgatcga ggcgagctgg
     7741 tgcagggcga cccaggcctg gccgagcgcc aggccggcgt cgccaggcga cagccgatgc
     7801 gcgccgagca cctcgaaacc ctgcgcggga agtgcggagt ggagcgcgtc ggcgagcagg
     7861 cgattgtgca ggcagccgcc ggacagcacc accgtggcgc cgccggttag cctgcgagcc
     7921 gcctcgatcc agtcgacgag cgccgcggcc agcgtggcct ggaaacacgc tgcgccgcgg
     7981 gcggcgtcgg gctcgtcggc gaggcacagc agcagggggt ggagatcgag ttcgagtcgg
     8041 ggcagggcgg gtgcgacggt gccggccgca tcggtaagga ttcgccagtc gccgcgatcc
     8101 accgccggcg cggccgtgct cgcggcgagc cgctcgagcg cgatcgccgc ctcggcctcg
     8161 ttctgcatca cctcgcacag gccgagcagg ccggcggcgg cgtcgaagtg gcggccgagg
     8221 ctggaggtcg gcgggcacag cgccggacgg gcgagcacct gggcgagcat cgccgccgcg
     8281 ggctgtcggg cgaagcgccg ggcgatctcg tcgccgcgcc cgctggcgtg caggaccgcg
     8341 gcggccatgc gccagggctc gcgcgccgcg cggtcgccgc cgggcaggcg cagcgggcgc
     8401 aggtggccga ggcgaacgca ctcgccgccc gccacccaca gcaactcgcc gccccaggcc
     8461 tcgccgtcgg tgccgaggcc gaccccgtcg agcgccaggc cgagcaccgg gcgcgcgtcg
     8521 aagcggccgt gctcggcgag caccgcgccg acgtgggcgt ggtggtgctg cacgccgatc
     8581 gccggcacgt ccaggcgcgc ggcgagcgcg caggcgacgc gggtggagtg gaagtcgggg
     8641 tggaggtcgt gggcgatcgc gcgcacgggg gcagccgcct gtgcgagcag ggccagcgcg
     8701 gccggctcca ccgcacggca ggcgtcggcg ttgtcgaggt cgccgaggtt ggggccgaat
     8761 tgcgcgcggc cgtcctcgag caggcaggcg gcgtgcttga accaggcgcc gagggccagg
     8821 atgggcggtg cttcggcgag cctgcgtgtg ccgacggggg gcagcgacag cgattcgccg
     8881 atcggtgcgg aggcggcttc tgcgggcatg ggcggcctgc ttgcttccat gtcggcgtcc
     8941 gggaaggtgg cgacgctcat gcgcgcacac ccgcggcacg ccccgcgcgc gcggtcgcga
     9001 gccccgcctc gatccaggcg atccattcgt ccaggccttc gcccgtggtg gccgaggtcc
     9061 gcagcacgcg caggcgcgga ttcacccgca gcgcgaagtc gatcgcgcgc ccggcgtcga
     9121 aggcgaggta gggcagcagg tcgaccttgt tgagcagcat caggtcggcg gcggcgaaca
     9181 tgtcggggta cttgagcggc ttgtcctcgc cctcggtgac cgagaggatc gccaccttgt
     9241 gcgcctcgcc gaggtcgaag gcggccgggc agacgaggtt gccgacgttc tcgatgagca
     9301 gcaggctgtc ctcggcgagt tccatgcgcg gcagcgcgcg cgcgaccatg tcggcgtcga
     9361 gatggcagcc cttgccggtg ttgatctgca gcgccggcac gccggtggcg cggatgcgct
     9421 cggcgtcgaa ctcggtctgc tggtcgccct cgatcaccgc cgcgggcacg cgcccgccga
     9481 gcagctgcag ggtgcgcacc agcagcgagg tcttgcccga gcccgggctg gacaccaggt
     9541 tgagcgcgaa gatgccgcgc gtggccagcc aggcgcggtt ctccgcggcg cgcgcgtcgt
     9601 tcttgccgag gatgtcgcgc tcgatcctga gcatctgcgc ctggctcagc ccgggcgcgt
     9661 gggcgtgcgc cgggccgctg ccgaagtcga ggtggtggtg gccgggtacg gtgtcgggca
     9721 cggccccagg gggcatggat gccggacggg ctggcgcggg gcgcgcgggg ggcgtcgggg
     9781 gcgtgggggc gtgctcgccg accgctcgcc atgcgcgggt ggcgccgggg tgcgggtgga
     9841 cggcaggtgc tgggcgtccg ccaccgagcg cgccgatccg ggtctcaccg cttccgcaac
     9901 cacatgtcgt gcacatcgtt cgtttctcct tgctggcggg tgaagcccgg ggagacgggt
     9961 tcgtgatcca gccacatgtt cagtcgacct ccagcgcctt gacgcgcatc tcccgtcccg
    10021 cgctcgcctg cacgcggtaa ccgccgcagc gcccgcaggc gtcatagagc tggtggatgg
    10081 ggaccgtctg cgcacaatcg gggcaccagc cggcgccggg cagggtttcg atctcgatcg
    10141 cggcgcccgc ggccacggtg tcggccagca cggcgcccag gcagaagcgc agcgcatcca
    10201 cctcgacggc ggcgagctcg ccgatctcca gcaccaccgt gcgcacgtgg cggaaccggt
    10261 cggcttgcgc ggcctcctcg atgatggcgc gcacgccctc ggccagggac atctcatgca
    10321 tcgcgattct cctctggctg cgagcttaaa cccagcgggg ggagaagggg agccgcgggg
    10381 gcggacgcga gacgaagggc gaggcgagga gaggcgggag tcggaggcgt cggcaggcgg
    10441 caggtgaagg acggtagggc acgcaggagc ggggcacgcg ccggggggcg gagacggccg
    10501 gagacagccg gtgacagcga gggaggcgcc cggcctctag aatggagtcc cgtctctcct
    10561 tgcccctgag tctcgcgatg aaagcgtctt ccttgctcgg cctcaccttc ctcgccgccc
    10621 ttgcaggtgg ctgcggccta ctcggccgtg ccgcgcctgc ggcatccgtc gaggcgacca
    10681 ccgcggctcc ggtccagcgc ccttccgcgc ccgcgctggc gctcgatccg cagcccccga
    10741 tcgagttccg ctgcggcgag cgcagggtcg agctgcgtca cttcggcgag ctcgccaccc
    10801 tcggcgtcga cggcaaggtg ttcacgctgc ggcccgagcg cagcgcctcg gggatgcgga
    10861 tggtgtcggt ggacgacgcc cgcaccggca tctgggtcaa gggcaactcc gcgctgctga
    10921 gcctcgccgg ggtcgagcag ccggagtgcc tgcgggtggc ggagaagccg ctgttccgcg
    10981 cggtcgggaa tgagccggcg tggcggctcg acatcggcgc gcaggggctg gagctgatcg
    11041 ccgacgacgg tgcctcgcgc gccttcgcct ccgcgccgct gatcgtggag gcggagggtc
    11101 tgcgcagcta ccagggcacg agcgccggcg gcgagctgga ggcgctggtg ttcgagcgcg
    11161 tctgcgtcga cacgatgagc gggatgacgc acccgaacac cgtcgaggtg cgctggcagg
    11221 agcgcgtgct gcgcggctgc ggcggcgatc ccgcgttgct gctgcagggc gagccctggg
    11281 aggtggtgga gctcgacggc agcgcagtga ccgatccggc gcggatcacg ctgggttttg
    11341 ccgcgggcgg acggcttgcg ggcggtgcgg ggtgcaaccg ctacttcggc agctacgcgc
    11401 tgtcgggcga gggcttgcgg ctgtcgccgc ggggggcgac acaaatggcc tgcgcgccgc
    11461 gcgcgatgga ggacgagcgg cgcttcatgg cggcggcggc aagcgtgagc ggatttgcga
    11521 tcacgaccga tggcaggctg gagctgcgcg ccggggagcg cgtggtgatg cgtgcacggc
    11581 gcgcttccgg ccccagatag ttgcggcggg cggggccggt gcgcgtcggg ggctgtgcgg
    11641 ctgcattcgc gcctgccggc gctcctgcaa caaccgtcgt ggtgctgggg gtggaggggg
    11701 tttgcgcctg ccggcgctcc tgcattgagc gtcggggttc cggggaggct acattcgcgc
    11761 ctgccggcgc tcctacatcg accgtcgggg ttccggggga ctgcacccgc gcctggcggt
    11821 gctcctgcat tgaccgccgg gcttccgggg aggctgcatt cgcgcctgcc ggcgctcctg
    11881 catcaaccgt cggggttccg gggttctgta ggagcggcgg cagccgcgaa tggggcggtg
    11941 gggtgggcga cgtgcgctca gccgcgcttg gcgcgggcgg cctcgacctc ttccgggcgc
    12001 aggcgggcgg cgagcttgtc gagcacgccg ttgacgaact tgtggccgtc ggtgccgccg
    12061 tagcccttgg cgagctcgat ggcctcgttg atcaccacgc ggtagggggt gtcgaggttg
    12121 tggcgcagct cgtgggtgcc gagcagcagg atcgcgtgct cgatcggcga cagctcggcg
    12181 accgggcgcg acagcagcgg ctcgaagcag ccgcgcagct cgtcggccgc gccggtggcg
    12241 ccgcgcagca ggctcacgaa cagctcgcgg tcgatcttgt cgaggttctc ggtctcggat
    12301 tcgaggtggc gctgcaccgt ggtggccgtg ttgcccgaca gcagccactg gtacaccccc
    12361 tgcagcgcga gctcacgcgc ccggcggcgg gccatcttgc tggtggggtt gggcgcgccg
    12421 gtgccgcctt cggcttgcgt gttgtcgatg tcgctcatcg caccaccttc agcaggttgg
    12481 ccatctcgac cgcggcgcgg gcgcagtcgg cgcccttctc gcgcatgcgc gcgaccgcct
    12541 ggtcgtcgtc ctcggtggtg agcacgccgt tggcgatcgg cagcccggtg tcgaggccga
    12601 cgcgggtgac gcccgcgccc atctcgttgg agacgagctc gaagtggtag gtctcgccgc
    12661 ggatcaccgc gccgagcgcg accagggcgt cgtgccggcc gctgcgggcc atggtctgca
    12721 gcacgagcgg gatctcgagc gcgccgggca cggtgacgat gcggatgtcc gcgcgcgcga
    12781 cgccgagggc gagcagctcg tcggtgcagg cggacagcag gccctcgcag atgtcgaggt
    12841 tgaagcgcgc catgacgatg ccgacgcgaa cgccggcgcc ggcgaagctc ggctcgatct
    12901 cgtcgatgcc gtcgtaacgg gcgccctggc gggcgttttc ggattggttg cgttgcatgc
    12961 tgggggttct ctggttcagt tcttgtcgac gaagccggtg atctcgaggc cgaagccggt
    13021 catgctcggg atcttgcgcg ggctggcgag caggcgcatc ttgccgacgc gcagcgcgcg
    13081 caggatctgc gcgccgacgc cgaacaggcg cgcatcccac ttcgcggtgg ggcggtcgtg
    13141 gccgccgttg aggccggcga gcagctcgcg gccggacatc gggcggtaga gcagcacgat
    13201 cacgccggcc tcggccgcgg ccagggtcgc gagcgcctgg ttgaccggga aggtgtggtg
    13261 gccgctgccg gcgtcgagga agtcgagcac cgagatcggc tcgtgcaccc gcaccagggt
    13321 ctcgcgctcg gggcggatgt cgccgtgcga cagggcgaaa tgcacgtcgc ccgaggtctt
    13381 gtcctcgaag gcggtgaggc ggaagcggcc gtggggggtg tcgacgtcct tctcggcgac
    13441 cttctcgacc aggtggtcgt tggcggcgcg gtactcgatg aggtcgcgga tggcgccgat
    13501 cttgagaccg tgcgcctggc cgaactcgac gaggtcgggc aggcgcgcca tggtgccgtc
    13561 gtccttgagg atctcgcaga tcaccgacgc gggctcgagc ccggcgagct gggcgaggtc
    13621 gcagccggcc tcggtgtggc cggcgcggat cagcacgccg cccttctgcg cggtgagcgg
    13681 gaagatgtgg cccggggtga cgatgtcgtc cgggcgggcg ttgcgggcga ccgcgacctg
    13741 cacggtgcgc gcgcggtcgt gcgccgagat gccggtggtg acgccggtgg cggcctcgat
    13801 cgagacggtg aaggcggtgc cgtgcggggt gcggttgtcg cgcaccatct gctgcaggcc
    13861 gagctggcgg cagcgctcgt cggtgagcgt caggcagatc aggccgcggc catgcttggc
    13921 catgaagttg atcgcctcgg gggtgacgaa ctcggccgcc atgacgaggt cgccctcgtt
    13981 ctcgcggtcc tcttcgtcta ccaggatgac catcctgccg gccttgatgt cggcgatgat
    14041 gtcggtgatc ggcgcgagtg cgctcatgct gcttcctttg tgttgcgttg gggcgcgcgg
    14101 gtcaggcctg cgcggcgtcg ttcttccact cgagcatgcg ctcgacgtag cgcgcgatga
    14161 ggtcgatctc gaggttgacc ttgctgcccg gcgcgaggtg cttgaggttg gtgaccgcga
    14221 ccgtgtgcgg gatcaggttg atccagaagt cgcgcccctc gacgcggttg accgtgaggc
    14281 tgacgccatt gacggtgacc gagcctttcc tggcgatgta gccggcgatc gccgccgggg
    14341 cgcggatcac cagctcgtgg ctctcgccga cgggcgcgaa cttcaccacc tcgccgacgc
    14401 cgtccacatg accggtgacc aggtggccgc cgaggcggtc ggccaggcgc agcgacttct
    14461 cgaggttgac ctcgccgccg accgtgtcga gccccacggt gcagttgagc gtctcgcgcg
    14521 agacgtcgta gcgcaggcgc gggccatcca tctcgaccac ggtgaggcac acgccgctgt
    14581 gcgccacgct gtcgccgacg atcacgtcgg agaggtcgag gccgttggtg tccacggtga
    14641 tgcgcacgcc gtccgcgagc gcctcgacgt gttcgatgcg gccgacggcc gcgacgatgc
    14701 cggagaacat gaagggtttg aaccgtaagg ggaaaggcgg gattgtaggg gaaaaacccc
    14761 ggccccgctc agagcgcccg gtccagcacc gtcgcgaacg gctccgcctt catgaagccc
    14821 accacgcgca tgccttcgcg ctccttgccc ctgccgtcga agaagatgat ccccggcggg
    14881 ccgaacaggc cgaagcgctt gagcagcgcc ttgtgctcgt cggtgttggc ggtgacgtcg
    14941 gccttgagca gcagcatgcg gcccatgcgc tcggcgaccg cggcgtcgct gaaggtgaag
    15001 cgctccatct ccttgcacga cacgcaccag tcggcataga aatcgagcag caccgggcgg
    15061 tcggtctgcg ccaggcgggc gtcgagcgcg gcgatggagt cgaccttctc gaactgcggc
    15121 aaattcaccg ccgccgcagc ctgcgcgcgc agcaccgaca agggctgcag cgggtcgcgc
    15181 gagccggcga gcgcgcccac caggatcgcc gcgccggcca gcagcagcac cacgcccacg
    15241 cccttccaga agcgctgcca gcccttggcc tgtggcggca gtgggtcgat ggcgtgcagg
    15301 aagatcgccg agaacagcag cagcgcggcc cagcccagca tcatcgccag cgccgggatc
    15361 accggggtga tcatccacag cgcgaccgcc agcagcatga cgccgaaggc cttcttgacg
    15421 ccctccatcc acggcccgac cttgggcagc aggctgcgcg aggccacgcc caccgccagc
    15481 agcggcgcgc ccatgcccag gcccatcgcg aacagcgccc agccgccgag caccgcgtcg
    15541 ccggtctgcg cgatgtagag cagcgcgcct gcgagcggcg cggccacgca gggcccgacg
    15601 atgagcgccg acagcacgcc catcagcgtg acgccgccga ggtggccgcc cttgccgtgg
    15661 ctggcggtgt cggccagccg gctctgcagc gcgctgggca gctgcagctc gtagaagccg
    15721 aacatcgaca gcgacagcag cacgaagagg agcgcgaagg ccgacagcac ccacacgttc
    15781 tgcagcgccg ccgacagcat cgtgccggtc atgccggcgg cgacgccggc gagcgcgtag
    15841 gtcgccgcca tgcccagcac gtaggcgagc gagagcacga aggcgcgcat gtgcgagacc
    15901 ttgttgccct ggccgacgat gatgcccgac aggatgggga tcatcgggaa ggtgcacggg
    15961 gtgaaggcga gcagcaggcc gaagccgaag aagctcagca ggatgatcgg cacgctggcg
    16021 ccggagagca ggcgggcgat gtcgccggtc tcgtcgctgg agacggcgtc ggcggcgggt
    16081 gagccggcgc cgtccgccgt cgcggccagc gccaccgggg cgctcgaggc gccgcccgcg
    16141 ccggcgcgcc cgccgagcac gctgtcgagg aagccgccgg ctttcttcgg cggcgcggtg
    16201 aggtcgatcg aggcctgctg cgtggtgggc gggtagcaga tgccgccgtc ccagcagccc
    16261 tggctggtgg cgaagagctc gaagcgcgtg gtgccgggag gcgcctgcac cggcaccagg
    16321 atgcgcagtt cgccgcggtg ggtctcgacc tcgccgaaga agtcgtcctt cttcatcttg
    16381 ccggccggct tctccagcgc accgaagccc acggcagcgg gctcggcctc gaagcggaac
    16441 ttgtcgccgt agaggtagta gtccttggcg atctcgaaca cgacctcgat ggtctgcgcg
    16501 tcgagcgcct gcgcgcgcat cgcgaaggcc ttctcgggct cgatcgggtt ggcgcgggcc
    16561 gcggtgggca ggagcaggct cgcgatcagg gcgagcagga ggaacaggcg gtgcatcgtg
    16621 gtcttctgtg cggcggtgtg cgggcgcgct gcggcgcggt cgggtgagtc gatcgggcgg
    16681 ggcgacgccg ggcgcttgcc ggcgggcttc atcgtgccgc cggcgctgcg agcgaggtgg
    16741 gcgcgcgtcg atggatgttc agtcatcgcc cgtcgtctcg aactcgaccc agtcgagata
    16801 gccgggcagg ccctgcatca cagggaccgc gacgatctcg ggaagttcgt aggggtggcg
    16861 cgcccggatc gccgcctcga gcgccgcgta gcgcgccggc gtggtcttga tcagcacggg
    16921 cacctcggtc gcggtttcgg tcgctccctg ccagcgatag atcgaggtgc agggggcgag
    16981 gatgttcacg caggcggcca ggcgccggcc gatcagcgcg ctcgccaagg tctcggcact
    17041 ggcggcgtcg ggcaggctgg tgaagacgag cagggcgcgc ggtgcgtcgg tcgtggcggc
    17101 tggactggcg ggcatgatgg cggatccgtc atggaacggc ggcgattatc ccgcagcgag
    17161 gccgcgcgtg ccctgcgcgg gatcaagcgc tgcgaggc
//
LOCUS       DAOTIN010000067        17139 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_4024_length_17139_cov_9.274584, whole genome shotgun sequence.
ACCESSION   DAOTIN010000067 DAOTIN010000000
VERSION     DAOTIN010000067.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 17139)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 17139)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17139
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4024_length_17139_cov_9.274584"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..2671
                     /gene="infB"
                     /locus_tag="P5537_10860"
     CDS             <1..2671
                     /gene="infB"
                     /locus_tag="P5537_10860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HRV78584.1"
                     /translation="RDELAEQAGAESAPVEPAELAEAVMEAPAAVEAVAPVAEAAAPV
                     AEAAAVEVAAVVEAAAPEAVEASEPVAAAPVAAVPAAEVEAPAPAQVVEAEAAAPVAA
                     PAAAAPAVAAARPAQQGGRHGRGERPPRQEPAPQPQVTTVLSKPLPLSEILSEEEIAA
                     RKRDEDRQRALKERQAADLRARQEREAAAKAAAEARKAEEEARLRAEQQKKEEPAKPA
                     AKPTTGTLHRPAKTEDKPAARDNKRAAPAAPAREADGASKRRGGMKTRGEVGATTGSN
                     WRGAGKGGGRHGRHQQDDRSSFQAPTEPIVREVHVPETITVADLAHKMAVKATEVIKA
                     LMKMGSMVTINQVLDQETAMIIVEEMGHLAVAAKLDDPDAFLEESDAHKDAEVLPRAP
                     VVTVMGHVDHGKTSLLDYIRRAKVASGEFGGITQHIGAYHVETSRGMLTFLDTPGHEA
                     FTAMRARGAKATDIVILVVAADDGVMPQTREAIHHAKAAGVPLVVAINKIDKPEANPE
                     RVTQELIAEEVIPEAYGGDTMFVPVSAKKGSGIDELLEAVLLQAEVLELTAPKDTPAK
                     GLIIEARLDKGRGPVASLLVQSGTLRKGDVLLAGATFGRIRAMLDENGKQIDEAGPSI
                     PVEVLGLSDVPAAGDEAIALTDEKKAREIALFRQGKFRDVKLAKQQAAKLETLMEQMT
                     EGEVKTLPLIIKADVQGSQEALVQSLQKLSTDEVRVNVIHAAVGAISESDVNLAQASG
                     AVILGFNMRADAGARKLAETFGVDIRYYNIIYDAVDEVKAALSGMLAPEKREEITGLV
                     EIRQVFTISKVGSIAGCYVLEGVVRRNSHVRLLRNHTVLWTGELESLKRFKDDVKEVK
                     FGYECGLQLRNYNDIHEGDQLEVFEIKEVARTL"
     gene            2675..3115
                     /gene="rbfA"
                     /locus_tag="P5537_10865"
     CDS             2675..3115
                     /gene="rbfA"
                     /locus_tag="P5537_10865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HRV78585.1"
                     /translation="MPKEYSRSQRVVEQIRRELAELIRLEVKDPRVGFITLTDVEITP
                     DYAHAKVFFTNMTGEADVPEILQGLRRASGFLRRELGRRIRIHTIPELHFHYDRSVEE
                     GSRLSQLIDEVVKEDEARQHDEAGGEDKAGEGRADEDDDARARG"
     gene            3093..4076
                     /gene="truB"
                     /locus_tag="P5537_10870"
     CDS             3093..4076
                     /gene="truB"
                     /locus_tag="P5537_10870"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004730 - pseudouridylate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HRV78586.1"
                     /translation="MTLAPAAEAAAPARPKRKGQPQRRIIRRAVDGVLLLDKPQGVSS
                     NGALQTARRLLNAAKAGHTGTLDPMASGLLPLTFGEATKFSQMLLDADKTYEAVVQLG
                     VDTDSGDAEGKVVATHPVAVDRIALESVLERFRGEIEQVPPMYSALKRDGKALYEYAR
                     AGIELEREARRVVIHALELLEFTGERFTIRVHCSKGTYIRSLAMDIGAALGCGAHLAA
                     LRRTAIGAFDLSGAVTLEALEAAGEGARDALLAPVDALVAGFPVLRLDAEAARGLLQG
                     RTLALAGAQPGAKVRAYGPEGFLGLAQWQDDGRLAARRLIATGDPGNDASA"
     gene            4154..4423
                     /gene="rpsO"
                     /locus_tag="P5537_10875"
     CDS             4154..4423
                     /gene="rpsO"
                     /locus_tag="P5537_10875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HRV78587.1"
                     /translation="MALDIASKSKIVSDFQRAQGDTGSPEVQIALLTARINGLAPHFK
                     EHAKDHHSRRGLLKMVSQRRKLLDYLKGRNADSYRNLIERLGLRK"
     gene            4642..6741
                     /gene="pnp"
                     /locus_tag="P5537_10880"
     CDS             4642..6741
                     /gene="pnp"
                     /locus_tag="P5537_10880"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HRV78588.1"
                     /translation="MPTAIKKTFAYGAHTVTLETGEVARQAGGAVIVNMDETVVLATV
                     VGAKEARPGQDFFPLTVDYVEKFYAAGRIPGGFFKREGRPSEKEILTSRLIDRPIRPL
                     FPDGFMNEVQVIVTVLSLNPEIDSDIPAMIGASAALAISGLPFNGPVGAARVGYLDGQ
                     YVLNPTATELQSSGMNLVVAGTQTAVLMVESEAQELPEHVMLGAVVFGHEQMQTAIKA
                     INELVEVAGKPEWNWQAPPANEPLIAKVAELAKAEMEEAFRITSKQERSARLSEIRKR
                     VIGQLTEGVENAPSVNELKDLFFNLESGIVRSRILNGEPRIDGRDTRTVRPIEIRTGV
                     LPRTHGSALFTRGETQALVVATLGTGRDEQIIDAIAGEYKERFLLHYNFPPFCTGETG
                     RFGVTKRREVGHGRLAKRSLVAMLPKPEEFSYTVRVVSEITESNGSSSMASVCGGSLA
                     MMDAGVPLKNHVAGIAMGLIKDGNRFAVLTDILGDEDHLGDMDFKVAGTENGITGLQM
                     DIKIQGITKEIMHAALEQAKEGRLHILGLMQQALGTSRGEVSEYAPRMINMKINPEKI
                     RDVIGKGGAVIRALQEETGTVIEIEDDGSVKISSVSAEGAQAAKAKIEAITAEVEVGK
                     VYEGPVVRLLDFGAIVNIMPGRDGLLHVSQIANERVNNVSDYVKEGQVVRVKVLETDE
                     RGKIRLSMKALLNENAG"
     gene            complement(6858..7283)
                     /gene="dksA"
                     /locus_tag="P5537_10885"
     CDS             complement(6858..7283)
                     /gene="dksA"
                     /locus_tag="P5537_10885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019899 - enzyme binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase-binding protein DksA"
                     /protein_id="HRV78589.1"
                     /translation="MAEDTLHKQFPPYVPAAGEEYMSEKQLAHFRAILDSLKGELVDD
                     IERTVHTMQDEATVFADPNDRASQESDIALELRNRDRERKLIKKIDETIARIEAGEYG
                     YCDSCGVEIGLKRLEARPTATLCIDCKTLEEMRERQVAK"
     gene            complement(7428..7916)
                     /locus_tag="P5537_10890"
     CDS             complement(7428..7916)
                     /locus_tag="P5537_10890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004386014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78590.1"
                     /translation="MQSSGEAAVTPRGIGPMLLGVPLAEAARETQRFDPAAGQIGPGC
                     DERDQISVVLRAAGESLSVMAMAGADANIEEILAIPADGAGAVTLADAEACRAHGAAF
                     AARLAPRLGEALAWSVRERPVSHEFVFPFAGDVRVVSRWFAGGKSCDLLLQFGSKAGT
                     AG"
     gene            complement(8024..8557)
                     /locus_tag="P5537_10895"
     CDS             complement(8024..8557)
                     /locus_tag="P5537_10895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006801 - superoxide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase family protein"
                     /protein_id="HRV78591.1"
                     /translation="MSKPSTTLFAALLATTLALPAFAAERASARIVDRQGAEVGSATL
                     VEGPHGVLIHVVAKGLPPGPKAIHIHSVGTCADGAQGFVASKGHLNPAARPHGLMNPD
                     GPDAGDLPNLFVHADGSVEAEFFTTLASLSGAGGRANILDADGAALVIHENRDDHSSQ
                     PIGGAGGRFFCGVIGAQ"
     gene            8714..10423
                     /locus_tag="P5537_10900"
     CDS             8714..10423
                     /locus_tag="P5537_10900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HRV78592.1"
                     /translation="MASSPDSISMALFCDFENVALGVRDAKYEKFDIKRVLERLLLKG
                     SIVVKKAYCDWDRYKSFKAAMHEANFELIEIPHVRQSGKNSADIRLVVDALDLCYTKS
                     HVDTFVIISGDSDFSPLVSKLRENAKQVIGVGVKQSTSDLLIANCDEFIFYDDLVRDS
                     QRAAAKREARDNPPASRRQPEEDKARREELESRRSKAIDIAVETFDALLAERGESGKI
                     WSSMLKEAIKRRKPDFNESYFGFRAFGNLLEEAQARGLLELGRDEKSGVFVTRPGPGL
                     AAPAAREEFATAAERVVAEPAAAGAGSGWEGVEADADAERVTAPAGASAEASASAPEP
                     RRGRGRSRGRGARAVEEAGAQPAAPEAHGAATVEARETAPESTPAALVVLAETVAPAA
                     AGSPVASSVPVEPAAAEPETVPGEARRSPATRRRRGGKADAPVAAAADVAAAAPIAAP
                     TAAAVDLLAVPAAASAAPAAGMDAAQDEKPKGKGKGKDKPKQKEKPSDAAKSSSRRGR
                     GGRGAGGKAAPEGADASASAAPAATSDASPDSRAPAASAPDTDKPAARPRRARKPKAE
                     SAE"
     gene            10420..11160
                     /gene="ugpQ"
                     /locus_tag="P5537_10905"
     CDS             10420..11160
                     /gene="ugpQ"
                     /locus_tag="P5537_10905"
                     /EC_number="3.1.4.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008081 - phosphoric diester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HRV78593.1"
                     /translation="MSAPAAAPWPYPFWIAHRGAGRLAPENTLAAFAVGHAHGYRMFE
                     CDARLSADGEVFLLHDDRLERTTDGRGEAVEQPWAALARLDAGAWHGSRHAGERLPRL
                     VEVLAFCRERGCMLNVEIKPAPGDEIRTGRRVAEVLSAEAFATSPLLSSFASAALAAA
                     AEVAPALPRGLLLETFRAAWLDEARALGCVAVIAECAAWTPPTAAQAAAAGLRRLAYT
                     VNDEAEAERLRALGLDSLITDRVDHFVP"
     gene            11237..12463
                     /locus_tag="P5537_10910"
     CDS             11237..12463
                     /locus_tag="P5537_10910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChaN family lipoprotein"
                     /protein_id="HRV78594.1"
                     /translation="MSSSSWLSALALTSGVLCTVPALANPVQGPSAPACLAPASWART
                     DTATPQRVDADGLLAAMAERAVVLLGEQHDDMDHHRWQLQTLATLHTLRPSMVIGFEM
                     FPRRVQPVLDRWVAGELTEAEFLQQAEWGKVWSMPAELYLPLFHFARLNRIPMLALNI
                     DAELTRRIADKGWDGVPEGEREGVGRPAAALPAYEDFLFEIHSQHAQMRMHGKDKARP
                     ARGDAAFRNFVESQLAWDRAMAEAMVAGRARHAAADGSLPLVVGIMGNGHVRHGHGVA
                     HQLAALGEPSVGQLMPVEAATPCAELPAGLADAVFAVPALRQPPPPPPRLGVGLEDAE
                     GGIRIAELTAGSLAERTGLRRGDLITEAAGAPVKRSGQLIGLIRRQPAGTWLPLQVMR
                     EGKAVEVVVRFPREAR"
     gene            12465..14534
                     /locus_tag="P5537_10915"
     CDS             12465..14534
                     /locus_tag="P5537_10915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002928081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family aminopeptidase"
                     /protein_id="HRV78595.1"
                     /translation="MLRALLAGVLLAGWLACLSPAEAAPVPARLHLAVELDPARGELQ
                     VEAVLRVPEAGYGFVLHESLQPQAASADGRALSLRAAGSRGSLRAWRVEAPAGAELRL
                     RYGGKLPALEQARDHREVLKAMPPMASPAGTFLASGSGWYPRPAELFAYEVDLVVRGG
                     QPALVAGRLAREQPPAAAGEPYRARFVFEHPADGIDLMAGPWVVRERLASQADGRALR
                     LRTYFPAALDAEAGLAEAYLADSQRYIERYAGQVGAYPFTEFSVVAAPLPTGFGMPTL
                     TYIGEQVLRLPFIRASSLGHEVLHNWWGNGVLVDYARGNWSEGLTTFMADYAYKSEES
                     AAAAREMRLGWLRDFAALPAGAHAPLADFRSRTHGAAAAVGYGKAAMVFVMLQDEIGE
                     DAFARGIRLFWARERFRTAGWDALRAAFEESAGRSLQGFFRQWLELPGGPAPRIERAR
                     LIEQAGQGARLRVVLTQPAPVHALRLPLRLVAGDRVETRIVEFAEGRAEVELTAGFVP
                     EGVALDPELRLWRLPEAAQLPPILRQWIVAAAPRLVVADALEEADAAGTGRGGEFAEA
                     AQALAGRLFERPPAEEGLAALTAEGGPVLLVGSVPAVATALDRAGLPAQPLDMPAGGT
                     ARVWTVQREAGPALAVIAAADPAALRALQRPLPHYGSQSWLVFDGARASARGVWQAPG
                     RSVAVER"
     gene            14649..15851
                     /locus_tag="P5537_10920"
     CDS             14649..15851
                     /locus_tag="P5537_10920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic murein transglycosylase"
                     /protein_id="HRV78596.1"
                     /translation="MSSRPLVLAAALAALSLPLSAAADEAAFASCLAKLRGEAAAKGV
                     RGDTFDAHTAALAPDMAVIGFLDAQPEFVTPIWDYLAALVDEERVADGRAMLAQWKEV
                     LAEVERRYGVEAETVVAVWGVESNYGRNFGSRPLLTSLSTLSCFGRRQAFFRGEFFTT
                     LKILQEGHVAPERLTGSWAGAFGHTQFMPSTFMRLAVDFDGDGRRDLIDSVPDALAST
                     ANFLKRAGWRSDLPWGFEVRLPRGMDTSDAGRRNKQPMAEWAARGVRRADGSALPAGG
                     APAGLMLPAGREGPAFLVTRNFDALYSYNAAESYGLAIAHLSDRLRGGVPFVAAWPTD
                     DPGLSRAERRELQQLLIARGHDIGEADGMIGARTREALQREQAALGLPADGRAGQRAL
                     QALRAAGR"
     gene            complement(16061..16831)
                     /locus_tag="P5537_10925"
     CDS             complement(16061..16831)
                     /locus_tag="P5537_10925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002928083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HRV78597.1"
                     /translation="MKPAPLQPRRLSDSIVERIETLVLEGSLRPGERLPAERALAEEF
                     GVSRPSVREAIQKLVARGLLVSRHGGGTFVNSTLGASFRDPMIELLGRNPEAQRDLIE
                     FRHTLEGACAYYAAQRATAPDRERLKAAFERVQDCYLQQGRISRADEGRADALFHLAI
                     AEASHNAVLLHTIRSLFELLEHNVVTNIGGMLPLGSAVRDKLLAQHQSLYDAIVGGRP
                     DDARRLASEHMDYVQEVLDETHDEARRIERAQRRREPA"
BASE COUNT         2500 a         6093 c         6155 g         2391 t
ORIGIN      
        1 gcgcgacgag ctcgccgagc aggctggcgc cgaatccgcg ccggtcgagc cggccgagct
       61 tgccgaggcg gtgatggaag cgcctgctgc ggtcgaggcc gtcgcgccgg tggccgaggc
      121 cgccgcgccc gtcgccgagg ccgccgccgt cgaagtggcg gcggtcgtcg aggctgcggc
      181 gccggaggcg gtcgaggcgt ccgaaccggt tgcggccgcg ccggtcgccg ccgtgcctgc
      241 cgccgaggtc gaggcgccgg cccccgcgca ggtggtcgag gccgaggcgg cggcacccgt
      301 cgccgcgccg gctgccgccg ccccggccgt tgccgccgcg cgtcccgccc agcagggcgg
      361 tcgtcatggc cgcggcgagc gcccgccccg ccaggagccc gcgccccagc cacaggtcac
      421 caccgtgctg agcaagccgc tgccgctctc cgagatcctc agcgaggagg agatcgccgc
      481 acgcaagcgt gacgaggacc gccagcgcgc cctcaaggaa cgccaggcgg cggacctgcg
      541 cgctcgccag gagcgcgagg ctgcggccaa ggcggctgcc gaggcgcgca aggccgagga
      601 agaagcccgc ctgcgtgccg agcagcagaa gaaggaagag ccggcgaagc cggctgccaa
      661 gccgaccacc ggcaccctgc atcgccccgc caagaccgag gacaagcccg ccgcccgcga
      721 caacaagcgt gccgcgcccg cggcgcccgc gcgcgaggcc gacggcgcca gcaagcgccg
      781 cggcggcatg aagacgcgcg gcgaggtcgg tgccaccacc ggcagcaatt ggcgcggcgc
      841 cggcaagggc ggtggccgtc acggccgcca ccagcaggac gaccgctcgt ccttccaggc
      901 gcccaccgag ccgatcgtgc gcgaggtgca tgtgcccgag acgatcacgg tcgccgacct
      961 cgcccacaag atggcggtga aggccaccga ggtcatcaag gcgctcatga agatgggctc
     1021 catggtcacc atcaaccagg tcctcgacca ggaaaccgcg atgatcatcg tcgaggagat
     1081 gggccacctt gcggtggcgg ccaagctcga cgacccggac gccttcctcg aggagagcga
     1141 tgcgcacaag gacgccgaag tcctgccgcg cgccccggtg gttaccgtca tgggccacgt
     1201 cgaccacggc aagacctcgc tgctcgacta catccgccgc gccaaggtcg cgtcgggcga
     1261 gttcggcggc atcacccagc acatcggtgc gtaccacgtc gagacctcgc gtggcatgct
     1321 gaccttcctc gacaccccgg gccacgaggc cttcaccgcg atgcgtgccc gcggcgccaa
     1381 ggccaccgac atcgtcatcc tggtggtcgc ggccgacgac ggcgtgatgc cgcagacgcg
     1441 cgaggccatc caccacgcca aggcggccgg cgtgccgctg gtggtggcga tcaacaagat
     1501 cgacaagccc gaagccaacc ccgagcgcgt gacccaggaa ctgatcgccg aggaggtgat
     1561 ccccgaggcc tacggcggcg acactatgtt cgtgccggtg tcggccaaga agggctccgg
     1621 catcgacgaa ctgctcgagg ccgtgctgct gcaggccgaa gtgctcgagc tcaccgcgcc
     1681 caaggacacc ccggccaagg gtctgatcat cgaggcgcgc ctcgacaagg gccgcggtcc
     1741 ggtggcctcg ctgctggtgc agtcgggcac cctgcgcaag ggcgacgtgc tgctcgccgg
     1801 tgccaccttc ggccgcatcc gcgcgatgct ggacgagaac ggcaagcaga tcgacgaggc
     1861 cggtccgtcc attccggtcg aggtgctggg cctgtccgac gtccccgcgg cgggcgacga
     1921 ggcgatcgcg ctcaccgacg agaagaaggc gcgcgagatc gcgctcttcc gccagggcaa
     1981 gttccgcgac gtcaagctcg ccaagcaaca ggccgccaag ctcgagaccc tcatggagca
     2041 gatgaccgag ggcgaggtca agaccctgcc gctgatcatc aaggccgacg tgcaaggttc
     2101 ccaggaggcg ctggtgcagt cgctgcagaa gctctccacc gacgaggtcc gcgtcaacgt
     2161 catccacgcc gcggtcggcg cgatcagcga gtccgacgtc aacctcgcgc aggcgtccgg
     2221 tgccgtcatc ctcggcttca acatgcgggc agatgccggc gcgcgcaagc tcgccgagac
     2281 cttcggcgtc gacatccgct actacaacat catctacgac gcagtggatg aggtgaaggc
     2341 ggcgctgtcg ggcatgctgg caccggagaa gcgcgaggag atcaccggcc tggtcgagat
     2401 ccgccaggtg ttcacgatct ccaaggtcgg ctcgatcgcg ggctgctacg tcctcgaagg
     2461 cgtggtgcga cgcaactcgc acgtccgcct gctgcgcaac cacacggtgc tgtggacggg
     2521 cgagctcgag tcgctcaagc gcttcaagga cgacgtcaag gaagtcaagt tcggctacga
     2581 gtgcggcctg cagcttcgca actacaacga catccacgaa ggcgaccagc tcgaggtctt
     2641 cgagatcaag gaagtggcga ggaccctgta agcgatgccc aaggagtatt cccgcagcca
     2701 gcgcgtggtg gagcagatcc gccgcgagct ggccgagctg atccggctcg aggtcaagga
     2761 tccgcgtgtc ggcttcatca ccctgaccga cgtcgagatc acccccgact acgcgcacgc
     2821 caaggtgttc ttcaccaaca tgacgggcga ggccgacgtg cccgagatcc tgcagggcct
     2881 gcgccgcgcg agcggcttcc tgcgccgcga gctcggccgc cgcatccgca tccacaccat
     2941 ccccgagctg cacttccact atgaccgttc ggtggaggag ggctcgcgcc tgtcccagct
     3001 catcgacgag gtggtgaagg aagacgaggc ccgccagcat gacgaggccg gcggcgagga
     3061 caaggccggc gaaggccgcg ccgacgagga cgatgacgct cgcgcccgcg gctgaggccg
     3121 cagcgccggc gcgtccgaag cgcaagggcc agccgcagcg caggatcatc cgccgcgcgg
     3181 tcgacggcgt gctgctgctc gacaagccgc agggcgtgag ctcgaacggc gcgctgcaga
     3241 cggcgcgccg cctgctcaat gccgccaagg ccggtcatac cggcacgctg gatccgatgg
     3301 cgagcgggct gctgccgctc accttcggcg aggcgaccaa gttttcgcag atgctgctcg
     3361 acgccgacaa gacctacgag gcggtggtgc agctcggcgt ggacaccgac agcggcgacg
     3421 ccgagggcaa ggtggtcgcc acccatccgg tggcggtgga tcgcatcgcg ctggagtcgg
     3481 tgctcgagcg cttccgcggc gagatcgagc aggtgccgcc gatgtattcg gcgctcaagc
     3541 gcgacggcaa ggcgctctac gaatacgcgc gcgcgggcat cgagctcgag cgcgaggcgc
     3601 gcagggtcgt gatccacgcg ctcgagctgc tcgagttcac cggcgagcgc ttcacgatcc
     3661 gcgtgcattg cagcaagggc acctacatcc gcagcctggc gatggacatc ggcgccgcgc
     3721 tcggctgcgg tgcgcatctg gccgccctgc ggcgtaccgc gatcggcgcc ttcgacctgt
     3781 ccggcgcggt cacgctcgag gccctggagg cggcgggcga gggcgctcgc gatgcgctgc
     3841 tcgcgccggt cgatgcgctg gtggcgggct tcccggtgct gcggctcgac gccgaggcgg
     3901 cgcgcggcct gctgcagggg cgcacgctcg cgctcgcggg cgcgcagccg ggtgcgaagg
     3961 tccgcgccta tgggcccgag ggcttcctcg gcctggcgca gtggcaggac gacgggcgcc
     4021 tggcggcacg caggctgatc gccaccggcg acccgggcaa cgatgcatcc gcatgatttt
     4081 gattgagtaa ctggcgcggc tttgggtata atccgccgct tctgattggc agaacacacg
     4141 agtaaagaca cacatggctc tcgatatcgc atccaagtcg aagatcgtct ccgacttcca
     4201 gcgcgcccag ggcgacaccg gctccccgga agtccagatc gcgctcctga ccgcccgcat
     4261 caacgggctc gccccccact tcaaggagca cgcgaaggat caccactccc gccgcggcct
     4321 cctgaagatg gtcagccagc gccgcaagct gctggactac ctcaagggtc gcaacgccga
     4381 cagctaccgc aatctgatcg agcgtctggg cctgcgcaag taattgccgt ccgtgacgag
     4441 tccgacagcg ccgatcaggg cgaagtaagc cagcaaagcc ggtgcgtgcc cctgcggccg
     4501 cgccggcttt ttgccattct tccgccgcgt tcgcgtgcgc cgtcgcgacc gtctctccgc
     4561 ggcgaccggc cgtccgctcg gacggcccgc cgcaagcagt tgtcgtctgc tgcatccacc
     4621 gaaagaacga ggaataccaa cttgcctacc gctatcaaga aaaccttcgc ctacggcgcc
     4681 cataccgtca ccctggagac cggcgaagtc gcccgccagg ccggcggcgc cgtcatcgtg
     4741 aacatggacg agaccgtggt gctggccacc gtggtcggcg ccaaggaagc ccgcccgggc
     4801 caggacttct tcccgctcac cgtcgactac gtcgagaagt tctacgccgc gggccgcatc
     4861 cccggcggct tcttcaagcg cgaaggccgt ccgagcgaga aggagatcct cacgtcgcgc
     4921 ctgatcgacc gcccgatccg cccgctcttc cccgatggct tcatgaacga agtccaggtc
     4981 atcgtcaccg tgctgtcgct gaaccccgag atcgactccg acatcccggc gatgatcggc
     5041 gcctcggccg cgctggcgat ctccggcctg cccttcaacg gcccggtcgg cgctgcgcgc
     5101 gtcggctacc tcgacggcca gtacgtcctc aacccgaccg ccaccgagct gcagtcgagc
     5161 ggcatgaacc tggtcgtcgc cggcacccag accgccgtgc tgatggtcga gtccgaagcc
     5221 caggagctgc ccgagcacgt catgctcggc gccgtggtat tcggccacga gcagatgcag
     5281 accgcgatca aggccatcaa cgagctggtc gaggtcgccg gcaagccgga gtggaactgg
     5341 caggcgccgc ccgccaacga gccgctgatc gccaaggtcg ccgaactcgc caaggccgag
     5401 atggaagagg ccttccgcat caccagcaag caggagcgct cggcacgcct gtccgagatc
     5461 cgcaagcgcg tgatcggcca gctcaccgag ggcgtggaga acgccccctc ggtcaatgag
     5521 ctcaaggacc tcttcttcaa cctcgagtcc ggtatcgtcc gcagccgcat cctcaacggc
     5581 gagccgcgca tcgacggtcg cgacacccgc accgtgcgcc cgatcgagat ccgtaccggc
     5641 gtgctgccgc gcacccacgg ctcggcgctg ttcacccgcg gcgagacgca ggcgctggtg
     5701 gtcgccaccc tcggcaccgg ccgcgacgag cagatcatcg acgccatcgc cggcgagtac
     5761 aaggagcgct tcctgctcca ctacaacttc ccgcccttct gcaccggcga gaccggccgt
     5821 ttcggcgtga ccaagcgccg cgaggtcggc catggccgtc tggccaagcg ctcgctggtc
     5881 gccatgctgc cgaagccgga agagttctcc tacaccgtgc gcgtggtttc cgagatcacc
     5941 gaatccaacg gctcctcgtc gatggcctcg gtgtgcggcg gctcgctcgc catgatggac
     6001 gccggcgtgc cgctcaagaa ccacgtcgcc ggtatcgcca tgggcctgat caaggacggc
     6061 aaccgcttcg ccgtgctgac cgacatcctg ggcgacgagg accacctcgg cgacatggac
     6121 ttcaaggtcg cgggcaccga gaacggcatc accggcctgc agatggacat caagatccag
     6181 ggcatcacca aggagatcat gcacgccgcg ctcgagcagg ccaaggaagg ccgcctgcac
     6241 atcctcggcc tcatgcagca ggccctgggc accagccgtg gcgaggtctc cgagtacgcc
     6301 ccgcgcatga tcaacatgaa gatcaacccg gagaagatcc gcgacgtgat cggcaagggc
     6361 ggagcggtga tccgcgcgct gcaggaagag accggcaccg tgatcgagat cgaggacgac
     6421 ggttcggtca agatctcgtc ggtcagcgcc gagggcgcgc aggctgccaa ggcgaagatc
     6481 gaggcgatca ccgccgaggt cgaggtcggc aaggtctacg aaggtccggt cgtgcgcctg
     6541 ctcgacttcg gcgccatcgt gaacatcatg ccgggccgcg acggcctgct gcacgtgtcg
     6601 cagatcgcca acgagcgcgt gaacaacgtc tcggactacg tcaaggaagg ccaggtcgtg
     6661 cgcgtcaagg tcctcgagac cgacgagcgc ggcaagatcc gcctgagcat gaaggcgctg
     6721 ctgaacgaaa acgccggctg atgccggcgg ggcgggctgc ggcccgccgc gcattgcagc
     6781 acggtgcgca gccaacaaaa aaggacgctc ccggcgtcct tttttgttgt ccgtcccggc
     6841 cgcggccggg ggagcgctta cttcgcgacc tggcgctcgc gcatctcttc cagcgtcttg
     6901 cagtcgatgc acagggtcgc ggtcgggcgc gcctctaggc gcttgaggcc gatctcgacg
     6961 ccgcagctgt cgcagtagcc gtactcgccg gcctcgatgc gggcgatcgt ctcgtcgatc
     7021 ttcttgatca gcttgcgctc gcggtcgcgg ttgcgcagct cgagcgcaat gtccgactcc
     7081 tggctggcgc ggtcgttggg gtcggcgaac acggtggcct cgtcctgcat cgtgtgcacc
     7141 gtgcgctcga tgtcatccac cagctcgccc ttgagcgaat ccaggatggc gcggaagtgg
     7201 gccagctgct tctcgctcat gtattcctcg cccgcggcgg gaacgtaggg cggaaattgc
     7261 ttgtgcagag tgtcttcagc catggatcga cttccgtaga tgggtgttga ttggtgaggt
     7321 ccgacttaat aacagaatca accgggtgca gcaagcatac cccgatcgta gccccgatcg
     7381 tcggcgcgtg cccagcctcc gggctcgtcg gcggggagat gcggcgatca gcccgccgtg
     7441 ccggccttgc tgccgaactg cagcagcagg tcgcagctct tgccgccggc gaaccagcgc
     7501 gacaccacgc gtacgtcgcc tgcgaaggga aacacgaact cgtgcgagac cgggcgctcg
     7561 cgcaccgacc aggcgagtgc ctcgccgagc cggggggcga gccgggcggc gaaggcagcg
     7621 ccgtgggcgc ggcaggcctc cgcatcggcc agcgtgaccg cgccggcgcc gtccgcgggg
     7681 atggcgagga tctcctcgat gttggcgtca gcgccggcca tcgccatcac cgacagcgac
     7741 tccccggcgg cgcgcaatac cacgctgatc tggtcgcgct cgtcgcagcc ggggccgatc
     7801 tgtccggccg ccgggtcgaa gcgctgcgtt tcgcgcgcgg cttcggcgag cggaacgccg
     7861 agcagcatcg gtccgatgcc gcgcggcgtg accgccgcct cgccggaaga ctgcatgcag
     7921 cccgcgccgc ccagagccag cgcgagcgca caggcgaacg tgcaggcgag cgcgggccgc
     7981 tgctgcgatc ggcccccgac caggattgag aggtccgccg tgctcactgc gctccgatca
     8041 cgccgcagaa gaagcgcccg ccggcgccgc cgatcggctg gctggaatgg tcgtcgcggt
     8101 tctcgtggat caccagcgcg gcgccgtcgg cgtcgaggat gttggcgcgc ccgcccgcac
     8161 ccgagaggct ggcaagggtg gtgaagaact ccgcctcgac gctgccgtcg gcatgtacaa
     8221 agaggttggg caggtcgccg gcgtcggggc cgtccgggtt catcagcccg tgcggcctcg
     8281 cggccggatt gagatggccc ttggaggcga cgaagccctg cgcaccgtcc gcgcaggtac
     8341 ctaccgagtg gatgtggatc gccttcggcc cgggcggcag gcccttggcg acgacgtgga
     8401 tcagcacgcc gtgcgggccc tcgacgagag tcgcactgcc gacctcggcg ccctggcgat
     8461 cgacgatgcg ggcgctcgcg cgctcggcgg cgaacgcggg cagggcgagg gtggtggcga
     8521 gcagggcggc gaacagggtg gtggagggct tgctcatcgg ttcttctcct attggatcca
     8581 gtccggagtt tcaagcatag gacagatcgg cgcgcatgca gcacccggca gcgagaggcc
     8641 gcgatggtac atcgggtggc acgtgccgcg gcgagggctt aacatcggcg gctcatcaga
     8701 aacggagatt tccatggctt cctcccccga cagcatcagc atggcgctgt tctgcgactt
     8761 cgagaacgtg gcgctgggcg tgcgggacgc gaagtacgag aagttcgaca tcaagcgggt
     8821 gctcgagcgc ctgctgctca agggcagcat cgtggtcaag aaggcctact gcgactggga
     8881 ccgctacaag agcttcaagg cggcgatgca cgaggccaac ttcgagctca tcgagatccc
     8941 ccacgtgcgc cagtccggca agaactcggc cgacatccgc ctcgtggtcg atgcgctcga
     9001 cctgtgctac accaagtcgc atgtcgacac cttcgtgatc atcagcggcg actccgactt
     9061 ctcgccgctg gtctccaagc tgcgggagaa cgccaagcag gtgatcggcg tcggcgtcaa
     9121 gcagtccacc tccgacctgc tgatcgccaa ctgcgacgag ttcatcttct acgacgacct
     9181 cgtgcgcgac agccagcgcg ccgccgccaa gcgcgaggcc cgcgacaacc cgcccgccag
     9241 ccgcaggcag cccgaggagg acaaggcccg ccgcgaggag ctcgagtcgc gtcgcagcaa
     9301 ggcgatcgac atcgccgtcg agaccttcga cgcgctgctc gccgaacgtg gcgagagcgg
     9361 caagatctgg tcgtcgatgc tcaaggaggc gatcaagcgc cgcaagcccg acttcaacga
     9421 gagctacttc ggcttccgcg ccttcggcaa cctgctcgag gaggcgcagg cgcgcggcct
     9481 gctcgagctc ggccgcgacg agaagtcggg cgtcttcgtg acccgccccg gtccgggcct
     9541 ggccgcgccc gcggcgcgag aggagttcgc gacggcggcg gagcgagtcg tggccgagcc
     9601 tgccgccgct ggtgcgggct cgggctggga gggcgtcgag gcggacgccg acgccgaacg
     9661 cgtcaccgcc cctgccggcg cgagcgcgga ggcgtctgcg agcgcgcccg agccgcggcg
     9721 cggccgtggt cgcagccgcg gacgtggcgc gcgtgcggtg gaggaggccg gagcgcagcc
     9781 cgcagcgccc gaggcgcacg gcgccgccac ggtggaggct cgggagaccg ccccggaaag
     9841 cacgccggca gcgcttgtcg tgctggcgga gacggtggcg ccggcggccg ccgggtcccc
     9901 cgtggcgtcc tcggtgcccg tcgagcctgc tgcagccgaa cccgagacgg tgcctggcga
     9961 ggctcgtcgt tctcccgcga cgcgccggcg gcgtggcggc aaggccgatg cgcccgtcgc
    10021 tgcggctgcc gacgtggccg ctgccgcgcc catcgctgcg cccaccgcgg ctgcagtgga
    10081 cctccttgcg gtcccggctg cggcgagcgc ggcccccgcc gctggcatgg acgccgccca
    10141 ggacgagaag ccgaagggca aaggcaaggg caaggacaag ccgaaacaga aggagaagcc
    10201 ctccgacgcc gccaagtcgt cgtcgcggcg ggggcgtggc gggcgcgggg cgggtggcaa
    10261 ggctgcgccg gaaggggcgg atgcttccgc aagcgcagcg cctgcggcga cctccgatgc
    10321 gtctcctgac agtcgtgcgc cggccgcgag cgcacccgat acggacaagc cggccgcgcg
    10381 tccgcgccgc gcgcgcaagc cgaaggccga gtcggccgaa tgagcgcgcc cgccgccgcg
    10441 ccctggccgt atccgttctg gatcgcccac cgcggcgccg gcaggctcgc gcccgagaac
    10501 accctcgccg cgtttgcggt cggccatgcg cacggctacc ggatgttcga gtgcgacgcc
    10561 cgcctgagcg cggacggcga ggtcttcctg ctccatgacg accgtctcga gcgcaccacc
    10621 gacggccgtg gcgaggcggt cgagcagccc tgggccgcgc tcgcacgcct ggacgcaggt
    10681 gcctggcacg gctcgcgcca cgccggcgag cgcctgccca ggcttgtcga ggtgctggcc
    10741 ttctgccgcg agcgcggctg catgttgaac gtcgagatca agcccgcacc cggtgacgag
    10801 atccgcaccg gacgccgggt ggccgaggtc ctctccgcag aggccttcgc cacgtcgccg
    10861 ctgctgagct ccttcgcctc tgccgcgctc gcggccgcgg ctgaggttgc gccagccttg
    10921 ccgcgcgggc tcctgctgga gaccttccgc gcggcttggc tggacgaggc gcgagcgctg
    10981 ggctgtgtcg cggtgatcgc ggaatgcgcg gcatggacgc cgccgacggc ggcgcaggcc
    11041 gctgcggccg gcctgcgccg gctcgcatac acggtgaacg acgaggccga agcggagcgc
    11101 ctgcgcgccc tcggcctcga cagcctgatc accgaccgcg tcgatcactt cgtcccctga
    11161 actgcgcggc agggggcgtg gaactcgcgt gcgcgcgcgg gctctaccgc ttgtcacgtt
    11221 ccccgagccc acgatcatgt cctcttcctc ctggctgagc gcgctcgcgc tcacgagtgg
    11281 tgtcctgtgc accgttccgg cgctggcaaa cccggtgcag ggcccgtccg cgcccgcctg
    11341 cctcgccccc gcgagctggg cgcgcaccga cacggcgacg ccgcagcggg tggacgcgga
    11401 cgggctgctg gccgcgatgg ccgagcgcgc ggtcgtgctg ctcggcgagc agcacgacga
    11461 catggaccac caccgctggc agctgcagac gctcgccacg ctgcacacgc tgcgcccctc
    11521 gatggtgatc ggcttcgaga tgttcccgcg ccgagtgcag ccggtgctcg accgctgggt
    11581 ggcgggcgag ctgaccgagg cggagttcct gcagcaggcg gagtggggca aggtgtggag
    11641 catgccggcg gagctctacc tgccgctctt ccatttcgcg cgcctgaacc gcatcccgat
    11701 gctcgcgctc aacatcgacg ccgaactcac ccggcggatc gccgacaagg gctgggacgg
    11761 cgtgcccgag ggcgagcgcg agggcgtggg ccgcccggcc gcggccttgc cggcctacga
    11821 ggacttcctc ttcgagatcc acagccagca cgcgcagatg cgcatgcacg gcaaggacaa
    11881 ggccaggccg gcgcgtggcg acgccgcctt ccgcaacttc gtcgagtccc agctcgcctg
    11941 ggaccgcgcg atggccgagg cgatggtcgc cggccgcgcg cgccacgcgg cggcggacgg
    12001 cagcctgccg ctcgtcgtcg gcatcatggg gaacggccac gtgcgccacg gccatggcgt
    12061 ggcccaccag ctcgccgcgc tcggcgaacc gagcgtgggc cagctcatgc cggtcgaggc
    12121 cgccacgccc tgcgccgagc tgcccgcggg cctcgccgac gcggtgttcg ccgtgccggc
    12181 gctgcgccag ccgccgcctc cgccgccgcg gctcggcgtc gggctggagg acgccgaggg
    12241 cggcatccgc atcgccgagc tcaccgcggg cagcctcgcc gagcgcaccg gcctgcgccg
    12301 tggcgacctg atcaccgagg cggcgggcgc gccggtgaag cgctccgggc agctgatcgg
    12361 cctgatccgc cgccagccgg cgggcacgtg gctgccgctg caggtgatgc gcgagggcaa
    12421 ggcggtcgag gtggtggtgc gcttcccgcg cgaggcgcgt tgagatgttg cgtgcgctgc
    12481 ttgcaggggt gctgctcgcc ggctggctcg cctgtctttc gcccgccgag gccgcgccgg
    12541 tgccagccag gttgcatctt gcggtcgagc tcgatccggc gcgtggcgag ctgcaggtgg
    12601 aggcggtgct gcgtgtgccc gaggccggct acggcttcgt gctgcacgag tcgctgcagc
    12661 cgcaggcggc gagcgccgac gggcgtgcgc tgtcgctgcg tgcggcgggc agccgcggtt
    12721 cgctgcgcgc gtggcgggtg gaggcgccgg ccggcgccga gttgcgcctg cgctacggtg
    12781 gcaagctgcc cgcgctcgag caggcacgcg accatcgcga ggtgttgaag gcaatgccgc
    12841 ccatggcctc gcccgcaggc acgttcctgg ccagtggcag cggctggtat ccccgtccgg
    12901 ccgaactctt cgcctacgag gtggacctcg tggttcgcgg cggccagccg gcgctggtcg
    12961 ccggccggct ggcacgcgag cagccccccg ccgccgcagg cgagccttac cgcgcgcgct
    13021 tcgtcttcga gcacccggcc gacggcatcg acctgatggc cgggccctgg gtggtgcgcg
    13081 aacgcctcgc ctcccaggcc gacggccggg cgttgcgcct gcgcacctac ttccccgccg
    13141 cgctcgacgc cgaggcgggg ctggccgagg cctacctcgc cgacagccag cgctacatcg
    13201 agcgctacgc cgggcaggtc ggcgcctatc ccttcaccga gttctcggtg gtggcggccc
    13261 cgctgcccac gggtttcggc atgcccacgc tgacctacat cggcgagcag gtgctgcgcc
    13321 tgcccttcat ccgcgcgagc tcgctcggcc acgaggtgct gcacaactgg tggggcaacg
    13381 gcgtgctggt cgactacgcg cgcggcaact ggtcggaggg cctgaccacc ttcatggcgg
    13441 actacgccta caagtcggag gagtcggccg ccgcggcgcg cgagatgcgc ctgggctggc
    13501 tgcgcgactt cgccgcgctg ccggcgggcg cgcatgcgcc gctcgcggat ttccgctcgc
    13561 gcacccacgg cgccgcggct gcggtgggct acggcaaggc ggcgatggtg ttcgtgatgc
    13621 tgcaggacga gatcggcgag gacgccttcg cgcgcggcat ccgcctgttc tgggcgcgtg
    13681 agcgcttccg caccgccggc tgggacgcgc tgcgtgccgc cttcgaggaa tcagcggggc
    13741 gctcgctgca gggcttcttc cggcagtggc tggaactgcc gggcggcccg gcgccgcgca
    13801 tcgagcgggc gcgcctgatc gagcaggccg ggcagggtgc gcgcctgcgc gtggtcctga
    13861 cgcagccggc gccggtgcat gccttgcggc tgccgctgcg gctcgtggcg ggtgatcgtg
    13921 tcgagacccg gatcgtcgag tttgcggagg ggcgagcaga ggtggagctg acggccggct
    13981 tcgtgcccga gggcgtggcg ctcgacccgg agctgcgcct gtggcgcctg ccggaggccg
    14041 cccagctgcc gcccatcctc cgccagtgga tcgtcgccgc agcaccgcgg ctggtcgttg
    14101 ccgacgcact ggaggaggcg gacgctgccg ggacgggccg aggcggcgag ttcgccgagg
    14161 cagcgcaggc gctggccggg cgactgttcg agcgtccgcc ggcggaggag gggcttgctg
    14221 cgctgaccgc cgagggtggg cccgtgctgc tcgtgggcag cgtgcctgca gtggcgaccg
    14281 cgctcgaccg cgccggcctg ccggcgcagc ccctggacat gcccgccggt ggcacggcca
    14341 gggtgtggac cgtgcagcgc gaggccggtc cggcgctcgc agtgatcgcc gccgccgatc
    14401 ccgccgcgct gcgcgcgctg cagcgcccgc tgccacacta cggcagccag agctggctgg
    14461 tcttcgatgg cgcgcgtgca agtgcccgcg gggtttggca ggcgcccggg cggtcggtgg
    14521 cggtggagcg ttgagcgcac ccggcacctt ggtcctggcg tgccggccat ccggtcgcca
    14581 aaccgcggta ccgtcttcac ggtgctagac tgccgcgccc acccgcaatc gaacaacagg
    14641 tcgtctccat gtcttcccgt cccctcgtgc tcgcggccgc gcttgcggca ctctcgctgc
    14701 ccctctccgc cgccgccgac gaggccgcgt tcgcctcctg cctcgccaag ctgcgtggcg
    14761 aggccgcggc caagggggtg cgcggcgaca ccttcgacgc ccacacggct gcgcttgccc
    14821 ccgacatggc ggtgatcggg ttcctcgacg cccagcccga attcgtcacc ccgatctggg
    14881 actacctcgc cgcgctggtg gacgaggagc gcgtcgccga cgggcgcgcg atgctggcgc
    14941 agtggaagga ggtgctcgcc gaggtcgagc gccgctatgg cgtcgaggcc gagacggtgg
    15001 tcgcggtgtg gggcgtggag agcaactacg ggcgcaactt cggcagccgg ccgctgctca
    15061 cctcgctgtc cacactgtcc tgcttcgggc gccggcaggc cttcttccgc ggcgagttct
    15121 tcaccacgct gaagatcctg caggagggcc acgtcgcccc cgagcgcctc accggctcgt
    15181 gggcgggcgc cttcggccac acccagttca tgccctcgac cttcatgcgc ctggcggtgg
    15241 acttcgacgg cgacggccgc cgcgacctca tcgacagcgt gcccgacgcg ctcgcctcga
    15301 ccgccaactt cctcaagcgc gccggctggc gcagcgacct gccctggggc ttcgaggtgc
    15361 gcctgccgcg cggcatggac acctccgacg ccggccgccg caacaagcag ccgatggccg
    15421 agtgggccgc gcgcggcgtg cggcgggccg acggcagcgc cttgcccgcg ggcggtgcgc
    15481 cggccgggct gatgctgccg gccgggcgcg agggccccgc cttcctggtc acgcgcaact
    15541 tcgacgcgct gtattcctac aacgccgccg agagctacgg cctcgcgatc gcccacctct
    15601 cggaccgcct gcgcggcggc gtgcccttcg tcgccgcgtg gccgaccgac gaccctggcc
    15661 tgtcgcgcgc cgagcgccgc gagctgcagc agctgctgat cgcgcgcggc cacgacatcg
    15721 gcgaggccga cggcatgatc ggcgcgcgca cccgcgaggc gctccagcgc gagcaggccg
    15781 cgctcggcct gccggccgac ggccgcgccg ggcagcgcgc gctgcaggcg ctgcgtgcgg
    15841 cggggcgctg agagggcgct gagagggcgc ttagagggcg ctcgggtgcg tccgcggcgc
    15901 gtcttcgcgc tcgtcgtttg acggtcaggc cgtcgccggc acggccccgg cggcccccaa
    15961 gccggttctc atgcaagcct cacggggccg gctcgccggt cgcgatcgcc gtccggctgg
    16021 cgtgctttcg gcggctgggc ggctgcggcc gcgccggcgc tcaggccggc tcgcggcggc
    16081 gctgcgcgcg ctcgatgcgt cttgcctcgt cgtgggtctc gtcgagcact tcctgcacgt
    16141 agtccatgtg ctccgaggcg aggcggcggg cgtcgtcggg ccggccaccg acgatcgcgt
    16201 cgtacaggga ctggtgctgg gcgagcagct tgtcgcgcac ggcgctgccg agcggcagca
    16261 tgccgccgat gttggtcacc acgttgtgct cgagcagctc gaacaggctg cggatggtgt
    16321 gcagcagcac cgcgttgtgg ctggcctcgg cgatcgcgag gtggaagagg gcgtcggccc
    16381 gcccctcgtc cgcccggctg atgcgcccct gctgcaggta gcagtcctgc acgcgctcga
    16441 aggcggcctt caggcgctcg cggtcggggg cggtggcgcg ctgcgcagcg tagtaggcgc
    16501 aggccccctc cagggtgtgg cggaactcga tgaggtcgcg ctgggcctcg gggttgcgcc
    16561 cgagcagctc gatcatcgga tcgcggaacg aggcgccgag cgtgctgttc acgaaggtgc
    16621 cgccgccatg gcggctcacc agcagcccgc gcgccaccag cttctggatc gcctcgcgca
    16681 ccgacggccg cgacacgccg aattcctcgg cgagcgcgcg ctccgcaggc aggcgctcgc
    16741 ccggccgcag gctgccctcg agcaccaggg tctcgatgcg ctcgacgatg ctgtccgaca
    16801 ggcggcgggg ctggagcggg gcaggtttca tcgagggggc gtcctgggtg gtggtgtggt
    16861 gcggggtgtg aatctagtcc ggcgggggcg tgggggcaag gggattgtcc gggctgtccg
    16921 gttcgacgcg tcggagtctt cccggctggt gtcgatcgtt gaaggtcctc gggatcgcca
    16981 ctgaggagcc gtccgagcga tcggcgccct ttcctagcat tggggagtcg aggggaggtg
    17041 cagcatgcgc gggtccccgc tcccatgggt ggcgctgggc gcggatgcct gcgggtgctc
    17101 ggcgccggcg ttttctgagc tgcctatccg gcagtgaat
//
LOCUS       DAOTIN010000068        17139 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_4025_length_17139_cov_9.267326, whole genome shotgun sequence.
ACCESSION   DAOTIN010000068 DAOTIN010000000
VERSION     DAOTIN010000068.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 17139)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 17139)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17139
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4025_length_17139_cov_9.267326"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..208)
                     /locus_tag="P5537_10930"
     CDS             complement(<1..208)
                     /locus_tag="P5537_10930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004372359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
                     /protein_id="HRV78598.1"
                     /translation="MCANYRPASREALAALPLPPPDFGYGEAYPGSVVPVVTNFAPRQ
                     WVAAVFGLVPAWAHDLKIIRSTYNA"
     gene            415..1758
                     /locus_tag="P5537_10935"
     CDS             415..1758
                     /locus_tag="P5537_10935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004372360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78599.1"
                     /translation="MPPELPTTSPRRRTLAAVLLFAMTVLAALAGTGHGPPVWIAGLA
                     AWGAAALLWPQLARAQKRQALLLAGAGAVAFGVALVRGGSPSLLGLLTQNTALLGMLA
                     AVSFLRLLRTPEAGSAGLPKGRGALWRTLGAVHVLGAVINLSAVFIMADRIGADGKPR
                     QDQAAVLVRAFLAAALWSPFFAATAVALTYAPGASPLGLAASGMALAVVLLWLAGRDT
                     ERSSGNRAADFIGYPMQASALKVPAVLAVLVGAGHWVVPEWAALAVISLAALVVVCVV
                     VLVQQGARAGGHALYGHVRDRLPGMSGELVLFLSAAVFASGLRALMDSGGLWLPFAAF
                     GVTEAALVLAAMILLAALGIHAVITIAMASAWLAPLQPEPTLLALVFVQSWAIGLAAG
                     PMSGIHLALQGRYGLSAAQLARANVRYCLQAYAAAVVWLAVIGSVLGVKLLPALS"
     gene            1769..2341
                     /locus_tag="P5537_10940"
     CDS             1769..2341
                     /locus_tag="P5537_10940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004372361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78600.1"
                     /translation="MEDLSDMETKKGKPGWRDVKGALVDFDRAGLLALVQDLYAASKD
                     NQVFLHARFGLGEDALEPYRVVIERWLCPDVYKNQDYSVAKARKPIADYKKAIGLPAG
                     LAELMVFYCEQATGFSAEFGLDDETYYGALVRMFGQALAIVAGLPEPQRASFLARLDV
                     VRAIGQNVGWGVGEEFDTLWRRAGFEIDGS"
     gene            2387..2677
                     /locus_tag="P5537_10945"
     CDS             2387..2677
                     /locus_tag="P5537_10945"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78601.1"
                     /translation="MADHEIPPELAALARRIQSLREEARALGLFAEDRGLLSCPACGL
                     QEDVTIGGRLITCDGNVAAGDDLGLRFVESPVGAFVCPRCGSPACREDDPEA"
     gene            2824..3159
                     /locus_tag="P5537_10950"
     CDS             2824..3159
                     /locus_tag="P5537_10950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004372364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78602.1"
                     /translation="MNYIMAVLIGFSVLLAGGTAMAVGAGQDGATAGAQVLEPQQGKK
                     EGAKAAVTEADPGNRASLLYIVLVGGVMVVAMKMAIAYGKKKLEEEREAAREKAALEE
                     RQKRSQAKG"
     gene            3472..4398
                     /locus_tag="P5537_10955"
     CDS             3472..4398
                     /locus_tag="P5537_10955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004372365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HRV78603.1"
                     /translation="MVRALYSRAGSHAGVGLLFLVLFVLYAERAFGLLPVDHALQAWL
                     EPVRNAAIALALFTAAHLLHALASARLSQRRKGRKPVPKVLLDLLRVFLFALATLGGL
                     SLLFRQDLSGILTGSGLVLAVLGFAIRNVVADTLSGIALGIEAPFRIGDWVRIENLAQ
                     GRVQEIGWRTTRLVTGDSTYVILPNSQISRQRITNFSAPKKEYRDHAELTLPVALPVA
                     EARELMRAALECAVGIAEDKPPEVQLVSYGPAGITYRVKYWVPQHDREPACRDEVLGL
                     IDAALRERGVVLAQVPLALSCAQQESIPYEAV"
     gene            4573..5598
                     /locus_tag="P5537_10960"
                     /pseudo
     CDS             4573..5598
                     /locus_tag="P5537_10960"
                     /inference="COORDINATES: protein motif:HMM:NF012711.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
     gene            5550..7001
                     /locus_tag="P5537_10965"
     CDS             5550..7001
                     /locus_tag="P5537_10965"
                     /inference="COORDINATES: protein motif:HMM:NF013702.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HRV78604.1"
                     /translation="MRELAAAVPRHGPDRYLARQPLPRHAPDPDVAAGFPRPPLRGHE
                     LCIVDARGRPLPERQVGMLEFRGPSATAGYYRNPEASAALFHDGWLSTGDHAYLAEGE
                     LYITGRAKEMIIRAGRNLYPYDLEQAVGALPGVRKGCVAVFGVQPGEPGQERLVVVAE
                     TRLRDEAERRALEQRILAEAMAQLELAPDDIVLAPMHAVLKTSSGKIRRAAVRDAYLD
                     GRLGAPARAAWLQILRLQLASLGGRLQALPGVLYAGWAWLGFALLAPLAALCILVLPT
                     IGQRWACAHRLARLYRWFCACPLRVEGLDRLPPGNCVLVANHASYCDGLVLAAALPRP
                     VRFVAKAEFRSNRILRPLFERMGALFVERFDARQGLEDAQALGAHAGEGLPMLFFAEG
                     TFGAREGLQAFRLGAFQVAARHSLPIVPVALAGTRAVLRDRSWWPRRGALALTVCAPV
                     EPRGDDWHDLLALRDAVRARILAHCGEHDALRG"
     gene            complement(7273..8616)
                     /locus_tag="P5537_10970"
     CDS             complement(7273..8616)
                     /locus_tag="P5537_10970"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78605.1"
                     /translation="MSLRPICFMVMPFGTKETGASAPHPPRVDFDALWHDAIAPALES
                     MGYRAVRADQDTGAVIVKEMLERLFFSHLVVADISIANANAYYEIGVRHAAREDNCVL
                     IAADWAKPVFDLQQIRRIGYPLPQEKVDADTARAIRAVLTKAIPEVRAGRSPVHSLIG
                     GYPQVPPNSRRAQELADQLEAFEMLRARMLAIRNMPREERDAAAEAFLAENPPACIGL
                     DTTAIEIFRFVRDVLGDWSRTAQFIDGLPETIRKSAYLREQRALAQSYLGSHTDAIAA
                     LEALIQTFGDSGERSGLIGGRYKKLYNASVKAGKPDRRMLDRAIEAYQRGMLLDLNDY
                     YCSCNLPALYRERGDDQDEQQAEAAAAVARLACERARQRGSADEWLKPTLLGLAFAEH
                     NHPLSRALTREVEREGADAWKLDSTLSDLHRHVAQMKDTAMQAEFTALIARLEAI"
     gene            complement(8646..10229)
                     /locus_tag="P5537_10975"
     CDS             complement(8646..10229)
                     /locus_tag="P5537_10975"
                     /inference="COORDINATES: protein motif:HMM:NF024758.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HRV78606.1"
                     /translation="MLDEHCTDEALIAYTRALLAEYPWPPAGESSRTAAALLDRLRAR
                     RQFALLAELADRVARRAPQDAHVRRLQAQALIETGQPSAAIDVIQAVLRKVEARSREW
                     AELNGLLGRAFKQIFIDARKALDATDLAALQNAVRAYRKPREADPSNTWHAINLVAVA
                     ACAERMHLRRVPRVDFRALARAILASPPTSDAWDAATRAEAHLALGELDELEEQIRRF
                     LAHDAIDAFAVASTLRQFEQVWELGQCGERSRVLLDAMRARLLGLPGGRCDLSLRELL
                     QSQQAGTAPNARLEAILGTDGTRSYRWWQAGLRSASSVASIRTGLDERIGTGFLVAPG
                     EFGVAAAGALLLTNFHVVNAQGSAGALRAEDASIVFEAVEPAAQYGVKRIVWSSPVDR
                     HDATLIELDGPPPANLEALSIARRLPVRPEDGPSRVYVIGHTGGGGLEFSFQDNELLD
                     HEGPRDNRFDATPCRLHYRAPTEKGNSGSPVFNAADWKVIALHHAGGTLSRLNGKPDT
                     YPANEGIALLSIISAMRAG"
     gene            complement(10248..>10792)
                     /locus_tag="P5537_10980"
     CDS             complement(10248..>10792)
                     /locus_tag="P5537_10980"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78607.1"
                     /translation="WWLKKRIMAAQLRDAHHYLFNIEHSPRAGVRYRVQDEIRLRFVS
                     ALKAVDSDRHVVVSHSMGTLIAYDCLKRVADCPSVDALVTLGSPLGLDEVQDCLEPEW
                     TRSDGYPANHLQGPWVNFFDPLDVVCGADPKLANDFRNAGQARVRDAQVANAGWWRHS
                     LVKYFGQPELRRTLRELLEI"
     assembly_gap    10793..10892
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(11147..12994)
                     /locus_tag="P5537_10985"
     CDS             complement(11147..12994)
                     /locus_tag="P5537_10985"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HRV78608.1"
                     /translation="MPTLSNPSEIAREALRQLALRRVAPTPDNYRKLYHEIAGTRPDD
                     DALPEAFVRKLARRLPRDNAERQRHGHQLDQALADGRSKAAEAALERYLESLKLGEPQ
                     AWNELIGNLLRQWEARQTGWTPARKREALDRVLGAADPAALYTRLQGLLKSWTQAMTD
                     ADALAVEVADVADDPAERASAGAGAGIARQAVPARTATTGPAAPPTIDTATVDALREL
                     VTISLGEALPPLLEEHPPLRETAATLCAEAASRSEAAGLREIGTRLRVFARELELAAA
                     DEAEIRAGMLELLRMLLRNIDDLVLDDRWLAGQIEMLREIVDSRPDPRKIDDAGRRLK
                     ELIYKQGQLKHTLAQSQRHLRDMLAGFVDQLARFSESTGAYHDRIGQCAQRIAQANDI
                     TEIGPLLDEVMTETRSIQDEARRSRDELIVARSQAAEAQERIVTLQNELEEASRLMRH
                     DQLTGALNRRGLEEMFQTESARAQRRGTRLAVALLDIDHFKKLNDSLGHKVGDDALVH
                     LAKVVRQHLRPQDVLARYGGEEFVILLPETGDTDAQQALIRLQRELTREFFMADLQKV
                     VITFSAGVTRLAEGESLESALKRADGAMYQAKQAGRNRVMVAPLPDNET"
     gene            13200..14828
                     /locus_tag="P5537_10990"
     CDS             13200..14828
                     /locus_tag="P5537_10990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_process: GO:0022904 - respiratory electron transport
                     chain [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetrathionate reductase family octaheme c-type
                     cytochrome"
                     /protein_id="HRV78609.1"
                     /translation="MDKNRCGWRRWIGGALILMASMMAGAANDPGAGKLPVAAAGGKA
                     ASTADHSKFKELQGPFKTGPEVTKACLACHNEAGHQVMKSVHWTWETISPTTGKKLGK
                     QHAANNFCGSILSNEPRCTSCHAGYGWTDKNYDFTNQDNVDCLACHDTTATYKKIATD
                     AGHPLYEPREMPKGSGKVVQPPDLTKIAQAVGKPGRQNCGACHFNGGGGDAVKHGDLD
                     TSLIKPPKHVDVHMSPDGANLSCADCHTFNAHQPSGSRYAATAKDTKGLDMKHEDHNR
                     ATCESCHDLRPHKNERLNNHANRLACQTCHIPEFARGGVATKTLWDWSTGGKRGPDGK
                     PLFIKDDHGHLIYSAEKGDFKYGENVRPTYKWYNGVVHQVAITDKIDDSKILELNRVE
                     GSASDPNARIWPFKVMVGKQPYDPVNKTLVVNHVYGKDDTAFWGNFDYEKSIKAGMDY
                     AGLPYSGKFDFIETRMNWFITHMVAPKEDALKCNDCHTRSEDGRLAAITDIYMPGRDR
                     NGWVDLLGGLAIIGAIGAGSVHGIARILTRRKGH"
     gene            14831..15487
                     /locus_tag="P5537_10995"
     CDS             14831..15487
                     /locus_tag="P5537_10995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b/b6 domain-containing protein"
                     /protein_id="HRV78610.1"
                     /translation="MSANRIYIYKRYERFWHWSQALLIIIMMITGFEIHGSYTFLGFK
                     KAVDLHTIAAWTLLVIWAFTIFWQFTTGEWRQYIPSMKNVSAMILYYTVGIFKEMPHP
                     FRKTTVQKHNPLQRLAYLALLAFISPLIWGSGLLYLFYGNWAQLGIDKTFSLEGVALV
                     HTAGAFMITAFFFIHVYLTTTGHTIFAHIKAMITGWEEVEDDHAPAAADHGKRAPGKA
                     "
     gene            complement(15542..15874)
                     /locus_tag="P5537_11000"
     CDS             complement(15542..15874)
                     /locus_tag="P5537_11000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78611.1"
                     /translation="MEKRWRRLPGSRTEPAGLERKVLARLPMVALVGTAACMAVSLLA
                     RLHWWSDDSIEAVRALQMIDIRVLAAVILHWTVVFTVAIGAFIVFVMKGPAYIADHYE
                     LPDEDAPR"
     gene            16129..16587
                     /locus_tag="P5537_11005"
     CDS             16129..16587
                     /locus_tag="P5537_11005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ProQ/FINO family protein"
                     /protein_id="HRV78612.1"
                     /translation="MTLQQAETAAPEPASTEAPEAAKQPRIEPRAILKRLQAESPAFR
                     DSKPLALKIDASILARFPDFDRKNLRIALRMHTASTKYLKAVERGGERFDLDGKAAGE
                     VTEEQRQHAAATLKERFAAVAKQQREKREAEEAERRRAEKLQQLVSKFGR"
     gene            complement(16610..16768)
                     /locus_tag="P5537_11010"
     CDS             complement(16610..16768)
                     /locus_tag="P5537_11010"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78613.1"
                     /translation="MQTITFRALLTLGLLAGLMIGTGHPGGALAVAIAAAAGIWMARA
                     DSVRRDLR"
     gene            16915..16990
                     /locus_tag="P5537_11015"
     tRNA            16915..16990
                     /locus_tag="P5537_11015"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16948..16950,aa:Thr,seq:tgt)
BASE COUNT         2483 a         5610 c         6129 g         2817 t
ORIGIN      
        1 gtgcgttgta ggtcgagcgg atgatcttca ggtcgtgcgc ccaggccggg accagcccga
       61 agacggcggc tacccactgt cggggggcga agttggtcac gaccggcacg accgagccgg
      121 gataggcctc gccgtagccg aaatccggcg gcggcagcgg cagcgcggcg agcgcttcgc
      181 gcgaggcggg gcggtagttg gcgcacatgg ggggcggtgc gagtctccgg gcggtcatta
      241 tcgccgatgc ggggggcggg gatgcagcgg cgcccggccg cgctgttcgc ggtgttcgtc
      301 ccgcaagtgg tcgatgccgc gcggtcgatg ccgcgctgtg tcgacatcgg catctggtag
      361 agaatgcatt ctcgcaagca aagcccccgc ggaccaacga cacccttcgc tcccttgccc
      421 cctgaattgc ccaccacctc tccccgccgc cgcacgctgg cggccgtgct gctgtttgcg
      481 atgacggtgc tcgccgcgct ggcgggcacc gggcatgggc cgcccgtgtg gatcgccggg
      541 ctggcagcct ggggcgcggc tgcgttgttg tggccgcagc ttgcgcgcgc gcagaagcgc
      601 caggcgctgc tgctggccgg tgcgggcgcg gtggcgttcg gcgtcgcact cgtacgcggg
      661 ggcagcccga gcctgctggg cttgctgacg cagaacaccg cgctgctggg catgctggcg
      721 gcggtgagct tcctgcgcct gctgcgcacg cccgaagccg gcagcgcagg cctgcccaag
      781 gggcgcggcg cgctgtggcg caccttgggc gcggtgcacg tgctgggcgc ggtgatcaac
      841 ctgtcggcgg tcttcatcat ggccgaccgc atcggtgcgg acggcaagcc gcgccaggac
      901 caggcggcgg tgctggtgcg cgccttcctc gccgcggcgc tgtggtcgcc cttctttgcc
      961 gccaccgcgg tggcgctgac ctatgcgccc ggcgccagcc cgctcggcct ggcggcatcc
     1021 ggcatggcgc tggcagtggt gctgctgtgg ctcgccggcc gcgacaccga gcgcagcagc
     1081 ggcaaccggg cggccgactt catcggctat ccgatgcagg cgtcggcgct gaaggtgccc
     1141 gcggtgctgg cggtgctggt gggggccggg cactgggtgg tgcccgagtg ggcggcgctg
     1201 gccgtcatca gcctggccgc gctcgtggtg gtgtgcgtcg tggtgctggt ccagcagggc
     1261 gcgcgggcgg gcggccatgc gctgtatggc catgtgcgcg accgcctgcc gggcatgtcg
     1321 ggcgagctgg tgctgttcct gtcggcggcg gtgttcgcca gcgggctgcg tgcgctgatg
     1381 gacagcggcg ggctgtggct gccctttgcc gctttcggcg tgaccgaggc ggcgctggtg
     1441 ctggcggcga tgatcctgct cgccgcgctc ggcatccacg cggtgatcac catcgccatg
     1501 gcgtcggcct ggctggcgcc gctgcaaccg gaaccgacgc tgctcgcgct ggtgttcgtg
     1561 cagtcgtggg cgatcggtct cgccgccggg ccaatgtccg gcatccacct cgcgctgcag
     1621 ggccgctacg gcctgtcggc cgcgcagctc gcacgcgcca acgtgcgcta ctgcctgcag
     1681 gcctatgcgg cggcggtggt gtggctggcg gtgatcggca gcgtgctggg cgtgaagctg
     1741 ttgccggcct tgagttgacc aaccctcgat ggaggatctg tcggatatgg aaacaaagaa
     1801 gggcaagcca ggctggcgcg acgtaaaggg cgcgctggtc gacttcgacc gggccggact
     1861 gctcgccttg gtccaggacc tgtatgccgc aagcaaggac aatcaggtct tcctgcacgc
     1921 ccgcttcggg ctcggtgagg atgcgctcga accctacagg gtggtgatcg agcgctggct
     1981 ttgcccggat gtgtacaaga atcaggacta ctcggtcgcg aaggccagga agccgatcgc
     2041 cgactacaag aaggcgatcg gcctgccggc ggggctcgcg gagctgatgg tgttctattg
     2101 cgagcaggcg accggtttca gcgccgagtt cgggttggac gacgagacgt actacggcgc
     2161 gctggtgcgg atgttcgggc aggcgctggc gatcgttgcg ggcttgcccg agccgcagcg
     2221 cgcgagcttt ctcgcgcggc tcgatgtcgt ccgcgcgatc gggcagaacg tgggctgggg
     2281 cgtgggcgag gagttcgaca cgctgtggcg acgcgccggc ttcgagatcg acggatcatg
     2341 agaatcctct ccgcctcctg cgcgcgcggc ccggacgtca tccgccatgg ctgatcacga
     2401 aattccgccc gagctggcgg ccctggcccg caggattcag tcccttcgcg aggaggcgcg
     2461 cgcgctcggt ctcttcgccg aggatcgcgg gctgctgagc tgtccggcct gcggcttgca
     2521 ggaagacgtt acgatcgggg ggcgtctgat cacctgcgat ggcaatgtgg ccgcaggcga
     2581 tgacctcggc ttgcgctttg tcgagtcccc ggtcggggcc ttcgtctgcc cgcgttgcgg
     2641 cagtcctgct tgccgcgagg atgatccgga ggcttagggt cgtgcggcgt cggacggctc
     2701 gggtgccaag ttccggcggg gctcttcagt acaatcacgc gatgttcgac agatcgatgc
     2761 gtcgcggcgc ggcttgcagg tgaagcgtca agtgtgtgac tggatcgacg aatgaggatt
     2821 ccgatgaatt acatcatggc agtgttgatc ggcttcagcg tcctccttgc gggcggcacg
     2881 gccatggccg tgggcgccgg acaggatggc gcgacggcag gcgcgcaggt gctcgaaccg
     2941 cagcaaggca agaaggaggg cgccaaggcg gccgtgaccg aggccgaccc gggcaaccgc
     3001 gcttctttgc tgtacatcgt cctcgtcggc ggcgtgatgg tcgtagccat gaagatggcg
     3061 atcgcctacg gcaaaaagaa gctggaagaa gagcgcgagg ccgcccgtga gaaagcggcg
     3121 ctcgaggagc gacagaagag gtcgcaggcg aagggctgag gacggcggga tgcgtgccgg
     3181 tttgcaggct tgccgctcga aattcgggac accgacgccc ccactgcacc ctgcaggtgc
     3241 gcccgtgcgt ttgaaagcgc aggatccatc cccatatagc ctgaagtggc cttcacggcc
     3301 attcccccag actttcggag accacgcgat gagctgccgc ggccgcgcga gattcgccct
     3361 gtgcatcgac caggcacatg cctggccccg gcctcgatag cgccttgccg gcgcggatcg
     3421 gcaggccggg gtcggtggag tgtcctttcc tctcgtctcg aaggtcctgc catggttcgc
     3481 gcgctgtact cccgcgccgg ctcgcatgcc ggtgtcggac tcctcttcct ggtgttgttc
     3541 gtcctgtacg ccgagcgggc gttcgggctg ctgcccgtcg accacgccct gcaggcctgg
     3601 ctcgagccgg tgcgcaacgc ggcgattgcg ctcgcgctgt tcaccgccgc gcatctgctg
     3661 catgcgctcg cgtcggcgcg gctgtcgcag cggcgcaagg ggcgcaagcc ggtgcccaag
     3721 gtgctgctcg acctgctgcg ggtgttcctg ttcgcgctgg caacgctggg cgggctgtcg
     3781 ttgctgttcc gccaggacct atcggggatc ctgaccggct cgggcctggt gctggccgtg
     3841 ctgggcttcg cgatccgcaa cgtggtggcc gacacgctgt cggggatcgc gctcgggatc
     3901 gaggcgccgt tccgcatcgg cgactgggtg cgcatcgaga acctcgcgca ggggcgggtg
     3961 caggagatcg gctggcgcac gacgcggcta gtgaccgggg acagcaccta cgtgatcctg
     4021 cccaacagcc agatctcgcg gcagcgcatc accaacttca gcgcgccgaa gaaggagtat
     4081 cgcgaccacg ccgagctgac cctgccggtc gcgctgccgg tggccgaggc gagggagctg
     4141 atgcgcgcgg cgctggagtg tgcggtgggc atcgccgagg acaagccgcc cgaggtgcag
     4201 ctggtgtcct acggcccggc gggcatcacc taccgggtga agtactgggt gccgcagcac
     4261 gaccgcgagc cggcctgccg cgacgaggtg ctcggcctca tcgatgcggc gctgcgcgaa
     4321 cgcggggttg tgctggcgca ggtgccgctc gcgctgtctt gtgcgcagca ggagtccata
     4381 ccgtatgagg ccgtctagac tgggcacatg caggtcggca agcgtgggtg cgcgcgcggt
     4441 gggcgggctc gccctcgtga tgcgcgagcg tggcgcatct ccctgctggt ccctgcgtgc
     4501 ccttttcggt gatcctgtac tcggccgcca ccgcgccgtg atgccggtgc ggcggcaata
     4561 aggagttcgg cgatgcccgc ctcgccacag tcttcgcacg gcccctccgc agctcgagat
     4621 cccgctccgc tgctggcgct gatcgacgcc ctggtgggcg aactgcagcc gggcgcgcgc
     4681 cggcaggcca cgctggacag ccagctcgac cgcgacctgg gcctggacag cctgagccgc
     4741 gtcgagctgc tggcgcgcat cgagcagcac taccgggtgc ggcttcgcga cgaggtgctg
     4801 ggtacggcac agacgccgcg cgacctgctc gctgccttgg gcgagtcggt cgctacgcat
     4861 gcgccaccgc ggccgcccgc ggaggcggtc gccgacagcg cgcgcatgtc cggcgaggat
     4921 gcggagctgc ccacggacgc ggccaccctg ctggaagtcc tcgactggca cctcgcccgc
     4981 caccccgatc gcgtgcatgt gcgcttctac gccagcgagg accgtgtcga agcgttgacg
     5041 tatgccggtc ttgccgacgg cgccggccgg gtggcgcagg cgctgcgcgc gctcgagatg
     5101 ggcgcgggcg actgcgtggc cctgatgctg ccttcggggc tggacttctt ccgctgcttc
     5161 ttcggcatcc tgcgcgcggg ggcggtgccg gtgccgatgt atccaccggc gcgcccggcg
     5221 cagatcgagg agcacctgcg ccgtcaggcc ggcatcctgc gcaactgcga ggcgcgggtg
     5281 ttgatcacct tcgatcgcgt gcgcccgctc gcgcgcatgc tcgccggcct ttcgcccgcg
     5341 ctcgcccatg tcgtcacgcc ggaaagcctg ctcgacgggc cgcgcccgcc cgctgcggag
     5401 ccgcccgccc cggggccggg cagcctggcg ctgatccagt acacttccgg ctcgaccggc
     5461 gaccccaagg gcgttgcgct gagccatggc aacctgctcg ccaacatccg cgcctggggc
     5521 gaggccgcgg cgctgacggc gagcgacgtg tgcgtgagct ggctgccgct gtaccacgac
     5581 atgggcctga tcggtacctg gctaggcagc ctctaccacg gcatgcccct gatcctgatg
     5641 tcgccgctgg atttcctcgc ccgcccctgc gcggacacga actgtgcatc gtcgatgcac
     5701 ggggacggcc gctgcccgag cgccaggtcg gcatgctcga gtttcgcggg ccctcggcca
     5761 ccgccggcta ctaccgcaat cccgaggcca gcgccgcgct gttccacgac ggctggctgt
     5821 cgaccgggga ccacgcctac ctggccgagg gcgagctcta catcaccggg cgggcgaagg
     5881 agatgatcat ccgcgccggg cgcaaccttt acccctacga cctggagcag gccgtgggcg
     5941 cgctgccggg ggtgcgcaag gggtgcgtcg cggtgttcgg cgttcagccc ggcgagccgg
     6001 gccaggagcg cctggtggtg gtggcggaga cccgcttgcg cgacgaggcc gagcgccggg
     6061 cgctggagca gcgcatcctc gccgaggcga tggcgcagct cgagctcgcg cccgacgaca
     6121 tcgtgctcgc gccgatgcac gccgtgctca agacctcgag cggcaagatc cgccgcgccg
     6181 cggtgcgtga cgcctacctc gacggccgcc tgggggcgcc ggcacgcgca gcctggctgc
     6241 agatcctgcg cctgcagctc gccagcctgg gcggacgcct gcaggcgctg ccgggggtgc
     6301 tctacgccgg ctgggcgtgg ctgggcttcg cgctgctcgc cccgctcgcc gccctgtgca
     6361 ttctcgtcct gccgaccatc gggcagcgct gggcgtgcgc ccaccgcctg gcacgcctgt
     6421 atcgctggtt ttgcgcctgc ccattacggg tcgaagggct cgaccggctt ccgcccggca
     6481 actgcgtgct ggtggccaac cacgccagct actgcgacgg gctcgtgctg gctgcggcgc
     6541 tgccgcggcc ggtgcgtttc gtggcgaagg ccgagttccg cagcaaccgc atcctgcgtc
     6601 ctttgttcga gcgcatgggt gcgctcttcg tggaacgctt cgatgcgcgc cagggattgg
     6661 aggatgcgca ggcgctcggc gcacacgccg gcgagggctt gccaatgctg ttcttcgccg
     6721 aggggacctt cggcgcccgc gagggcctgc aggccttccg cctgggggcc ttccaggtgg
     6781 cggcccggca cagcctgccc atcgtcccgg tggcgctggc cggcacccgt gccgtgctgc
     6841 gcgaccgcag ctggtggccg cggcgcggcg cgctcgcgct gaccgtgtgt gcccccgtcg
     6901 agccacgcgg cgacgactgg cacgatctgc tcgccctgcg cgatgcggtg cgggcacgga
     6961 ttctggcgca ttgcggcgaa cacgatgctc tgcgcggctg agaaggccgg cgggcgtcgt
     7021 cgtccgaaag cggcgggccg ttggcacatt gggcgccgat gatgcgacga gaagaggggg
     7081 gccgtcgcgc gaacgatagc gtgcagcccc gcctcggccg gacggatgcg cgggatgtgg
     7141 cgcagtgagg tcgggtcggg acgccagtcg aggatgatgt gatccggtct gtcctccacg
     7201 ccgcagggcc gcgcgatgtc ccgccccgcc cgcgcctttc gttgacggcg ttgagccccg
     7261 gcccggccgg gatcagatcg cttcgagccg cgcgatcagc gccgtgaact ccgcctgcat
     7321 cgccgtatcc ttcatctgtg cgacatggcg gtgcaggtcg gacagggtgg aatcgagctt
     7381 ccaggcatcg gcgccttcac gttcgacctc gcgggtgagc gctcgcgaca aggggtggtt
     7441 gtgctcggca aaggcgaggc cgagcagcgt cggcttgagc cactcgtccg cgctgccgcg
     7501 ttgacgtgcg cgttcgcagg ccaggcgcgc gacggcggcc gcggcctcgg cctgctgctc
     7561 gtcctggtcg tcgccgcgct cgcgatagag cgcggggagg ttgcagctgc agtagtagtc
     7621 gttgagatcg agcaacatgc cgcgttggta ggcttcgatg gcgcggtcga gcatgcggcg
     7681 atcgggcttg ccggccttga ccgaggcgtt gtaaagcttc ttgtagcgtc cgccgatcag
     7741 gccgctgcgt tcgccgctgt cgccgaaggt ctggatcagc gcctccagcg cggcgatcgc
     7801 gtcggtgtgc gaccccaggt agctctgcgc cagcgcgcgc tgctcgcgca ggtaggcgct
     7861 cttgcggatc gtctccggca gtccgtcgat gaactgcgcg gtccggctcc agtcaccgag
     7921 cacgtcgcgg acgaagcgga agatctcgat cgcggtggtg tcgagcccga tgcaggctgg
     7981 cgggttctcg gcgaggaagg cttcggccgc cgcgtcgcgc tcttcccgcg gcatgttccg
     8041 gatcgccagc atgcgtgcgc gcagcatctc gaaggcttcg agctggtcgg cgagctcctg
     8101 cgcgcggcgg ctgttggggg gaacctgcgg gtagccaccg atgagggaat gcaccgggga
     8161 gcgcccggcg cgcacctcgg gaatcgcctt cgtcagaacc gcgcggatgg cacgcgcggt
     8221 gtcggcatcg accttctcct gcggcagggg atagccgatg cggcggatct gctggagatc
     8281 gaacaccggt ttcgcccagt ccgcggcgat cagcacgcag ttgtcctcgc gggcggcatg
     8341 gcgaacgccg atctcgtagt aggcgttggc gttggcgatg ctgatgtcgg ccaccaccag
     8401 gtgcgagaag aacaggcgtt cgagcatctc cttgacgatc accgcgccgg tgtcctggtc
     8461 tgcgcgcact gcgcggtaac ccatggattc gagcgcgggc gcgatcgcat cgtgccacag
     8521 ggcgtcgaag tcgaccctcg gtggatgcgg cgcgctcgca ccggtttcct tggtgccgaa
     8581 gggcatcacc atgaagcaga tcgggcgcag gctcatttcg ggctcctttg gccttggagg
     8641 gccggtcagc cggcgcgcat cgcgctgatg atcgagagca gcgcgatgcc ttcgttggcc
     8701 gggtaggtgt cgggcttgcc attgagccgc gacagggtgc cgcccgcgtg gtggagggcg
     8761 atcaccttcc agtcggcggc gttgaagacc gggctgccgg agttgccctt ttcggtcggc
     8821 gcacggtagt ggaggcggca gggcgtggcg tcgaagcggt tgtcgcgcgg cccctcgtga
     8881 tcgagcagct cgttgtcctg gaaggagaac tcgagaccgc ctccaccggt gtggccgatg
     8941 acgtagacgc ggctcgggcc atcctccggt cgcacaggaa ggcgccttgc gatcgacagc
     9001 gcttcgaggt tcgcgggcgg cggcccgtcg agctcgatga gcgtggcgtc gtggcgatcc
     9061 accggcgaac tccacacgat gcgcttcacg ccgtactgcg ctgccggctc gactgcctcg
     9121 aacacgatcg aggcatcctc cgcccgcagc gcgcccgcgc tcccttgcgc gttcacgacg
     9181 tggaagttgg tcagcagcag cgcgcccgcc gcggcgacgc cgaattcgcc cggtgcgacg
     9241 aggaagccgg tgccgatgcg ctcgtcgagg ccggtacgga tcgaggccac cgaggatgca
     9301 ctgcgcagcc cggcctgcca ccagcgatag gatctggtgc cgtcggtgcc gaggatggct
     9361 tcgagccggg cgttcggcgc tgtgccggcc tgctgcgatt gcaggagttc gcgcagggac
     9421 aggtcgcaac gccctcccgg caggccgagc aggcgggccc gcatggcgtc gagcaggacc
     9481 cggctccgct cgccgcactg gccaagctcc cagacctgct cgaactggcg cagcgtgctg
     9541 gccacggcga aggcgtcgat cgcgtcatgc gcgaggaagc ggcggatctg ctcttcgagc
     9601 tcgtcgagct cgccgagcgc gaggtgggct tcggcacgtg tggctgcgtc ccacgcatcc
     9661 gacgtcggcg ggctggccag gatggcgcgc gccagcgcgc ggaaatccac tcgtggcacc
     9721 cggcgcaggt gcatgcgctc ggcgcaggcc gcgactgcga cgaggttgat ggcatgccat
     9781 gtgttcgacg gatcggcctc ccggggcttg cggtaggcgc gcacggcgtt ctggagcgcg
     9841 gcgaggtcgg tggcgtccag ggccttgcgt gcatcgatga agatctgctt gaaggcgcgc
     9901 ccgagcaggc cgttcagctc ggcccattcc ctgctccggg cctcgacctt gcgcaggacg
     9961 gcctggatga catcgatggc tgcgctgggc tggccggtct cgatcagcgc ctgcgcctgc
    10021 agcctgcgca cgtgcgcatc ctgcggggcg cgacgtgcga cgcggtcggc gagttcggcg
    10081 agaagggcga actggcgccg tgcgcgcaga cggtcgagca atgcggcggc ggtgcgcgac
    10141 gattcgcccg ccggcggcca cgggtattcg gccagcagcg cgcgggtgta tgcgatcaag
    10201 gcctcgtcgg tgcagtgctc gtcgagcatg ggtgcggggc ctcggcgtca gatctcgagc
    10261 agctcgcgca gggtccggcg cagttccggc tggccgaagt acttcaccag cgagtgccgc
    10321 caccagcccg cgttggcgac ctgggcatcg cggacgcgtg cctggccggc gttgcggaaa
    10381 tcgttggcga gcttcgggtc ggcgccgcag acgacgtcga gggggtcgaa gaaattcacc
    10441 cacggtccct gcaggtggtt ggccgggtag ccgtcgctgc gggtccattc cggctcgagg
    10501 cagtcctgca cttcgtcgag gccgagcggg ctcccgaggg tgacgagggc gtcgaccgac
    10561 gggcagtcgg caacgcgttt gaggcagtcg taagcgatga gcgtgcccat gctgtgcgac
    10621 accaccacat gacgatcgct gtcgaccgcc ttcagggccg agacgaagcg caggcggatc
    10681 tcgtcctgga cgcgatagcg gacgccagcg cgcggggaat gctcgatgtt gaagaggtaa
    10741 tgatgcgcgt cgcgcaactg cgccgccatg atgcgcttct tcagccacca ggnnnnnnnn
    10801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nncggctggt cacgccggtg gcgcgcaggt
    10921 cgagcgggtc atcgcccttg gccagtgcgc gtagccagat ctcgtagagc ttctccgcct
    10981 cgggcttgtt ggccaggcca tggatgaacg tgacgtgcgg catttgcggc tcctgcagag
    11041 tcctgcccag aacgacaatt gcccgtctga aagtcgcggg cccccctcct tttcaagata
    11101 gggcatttcc cgctggcgac aagcgggcgt ttgctgtcgg agcggttcag gtctcgttgt
    11161 cgggtagcgg cgccaccatc acgcggttgc ggccggcctg cttggcctgg tacatcgcgc
    11221 cgtcggcgcg cttcagtgcg ctctccaggc tttcgccttc cgccaggcgg gtgacgccgg
    11281 cgctgaaggt gatcaccacc ttctgcaggt cggccatgaa gaactcgcgc gtgagctcgc
    11341 gttgcaggcg gatgagcgcc tgctgggcgt cggtgtcgcc ggtctcgggc agcaggatga
    11401 cgaactcctc gccgccgtag cgggcgagca cgtcctgcgg gcgcaggtgc tggcgaacga
    11461 ccttggcgag gtgcaccagg gcgtcgtcgc cgaccttgtg gccgaggctg tcgttgagct
    11521 tcttgaagtg gtcgatgtcg agcagggcga cggcgagccg ggtgccgcgg cgctgggcgc
    11581 gcgcggattc ggtctggaac atctcctcga ggccgcggcg gttgagcgcg ccggtgagct
    11641 ggtcgtggcg catcaggcgg ctggcctcct cgagctcgtt ctgcagcgtg acgatacgct
    11701 cctgcgcttc ggcggcctgg ctgcgggcga cgatgagctc gtcgcgcgag cggcgcgcct
    11761 cgtcctggat gctgcgggtc tcggtcatga cctcgtcgag cagggggccg atctcggtga
    11821 tgtcgttggc ctgggcgatg cgctgggcgc actggccgat gcggtcgtgg tatgcgccgg
    11881 tcgattcgga gaagcgcgcg agctggtcga cgaagccggc gagcatgtcg cgcaggtgac
    11941 gctgggactg ggccagggtg tgcttgagct ggccctgctt gtagatgagc tccttgaggc
    12001 ggcgcccggc gtcgtcgatc ttgcgcgggt cggggcggct gtcgacgatc tcgcgcagca
    12061 tctcgatctg cccggcgagc cagcggtcgt cgagcacgag atcgtcgatg ttgcgcagca
    12121 gcatgcgcag cagctccagc atgccggcgc ggatctcggc ttcgtcggca gcggcgagct
    12181 cgagctcgcg cgcgaaaacg cgcagccggg tgccgatctc gcgcaggccg gcggcttcgc
    12241 tgcggctggc ggcctcggcg cagagcgtgg cggcggtctc gcgcagcggc gggtgttctt
    12301 caagcagcgg cggcagggcc tcgccgaggc tgatggtgac gagctcgcgc agggcgtcca
    12361 ccgtggcggt gtcgatggtg ggcggagcgg cgggtcccgt cgtcgcggtg cgtgctggca
    12421 cggcttgcct cgcgatgcca gcgccggccc cggcgctcgc cctctccgca gggtcgtccg
    12481 ctacgtcggc gacctcgacg gcgagcgcgt cggcgtcggt catcgcttgc gtccagctct
    12541 tgagcaggcc ctgcaggcgg gtgtacagcg ccgctggatc ggccgcgccc agcacgcgat
    12601 cgagcgcctc gcgcttgcgc gccggggtcc agccggtctg gcgcgcctcc cactgccgca
    12661 ggaggttgcc gatgagctcg ttccaggcct gcggttcgcc cagcttgagg ctttcgaggt
    12721 agcgctcgag cgcggcctcc gcggccttgc tgcggccgtc ggcgagcgcc tggtcgagct
    12781 ggtggccgtg gcgctggcgc tcggcgttgt cgcgcggcag gcggcgggcg agcttgcgca
    12841 cgaaggcctc ggggagtgcg tcgtcgtcgg ggcgcgtgcc ggcgatctcg tgatagagct
    12901 tgcggtagtt gtccggcgtg ggggcgaccc ggcgcagcgc gagctggcgc agggcttcgc
    12961 gggcgatttc ggagggattg ctgagcgtgg gcatgatgcg tgtcggaggt cccgggggct
    13021 ggcgcatgtt tgccgcattt tgacagcagt tcttgagctt tcggcgggca atttgccaac
    13081 agggggccgc gagggagtcg cgcgcgcgcg atctgccaat ccgtagacat taatcaaatg
    13141 cttatataga gagtcgcgct aaactatcaa aggagatgtt tccttcggag gaaagggtga
    13201 tggacaagaa tagatgcggc tggcgtcgct ggatcggtgg agcgttgatc ctgatggcca
    13261 gcatgatggc gggcgcggcg aacgaccctg gcgcgggcaa gctgcccgtc gctgcagcgg
    13321 gcggcaaggc ggcgagcact gcggaccaca gcaagttcaa ggaactgcag gggcctttca
    13381 agaccggtcc ggaagtcacc aaggcctgtc ttgcctgcca caacgaggcc ggccaccagg
    13441 tcatgaagag cgtgcactgg acctgggaga ccatcagtcc gaccaccggc aagaagctgg
    13501 gcaagcagca cgcggccaac aatttctgcg gctcgatcct ctccaatgag ccgcgctgca
    13561 cgagttgcca cgctggctac ggctggacgg acaagaacta cgatttcacc aaccaggaca
    13621 acgtggattg cctggcctgc cacgacacga ccgcgaccta caagaagatc gccaccgatg
    13681 ccggccatcc gctctacgag ccgcgcgaga tgcccaaggg cagcggcaag gtcgtgcagc
    13741 cgcccgacct gacgaagatc gcgcaggcgg tgggcaagcc cggccggcag aactgcggcg
    13801 cctgccactt caacggcggc ggcggtgacg cggtcaagca cggcgacctc gacacctcgc
    13861 tgatcaagcc gccgaagcat gtcgacgtgc atatgtcgcc cgacggtgcg aatctgtcct
    13921 gtgccgactg ccacaccttc aacgcccacc agccctccgg cagccgctat gcggctaccg
    13981 ccaaggacac caagggcctg gacatgaagc acgaggacca caaccgggcg acctgcgagt
    14041 cctgccacga tctgcgcccg cacaagaacg agcgcctcaa caaccacgcc aaccgcctgg
    14101 cctgtcagac ctgccatatc ccggagttcg cgcgtggcgg tgtcgccacc aagacgctct
    14161 gggactggtc gaccggcggc aagcgcggtc ccgacggcaa gccgctgttc atcaaggacg
    14221 accacggcca cctgatctac tcggccgaga agggcgactt caagtacggc gagaacgtgc
    14281 gcccgaccta caagtggtac aacggcgtgg tccatcaggt cgccatcacc gacaagatcg
    14341 acgacagcaa gatcctcgag ctcaaccgcg tcgaaggctc ggcgagcgat ccgaacgccc
    14401 gcatctggcc cttcaaggtc atggtcggca aacagcctta cgacccggtg aacaagaccc
    14461 tggtggtcaa ccacgtgtat ggcaaggacg acaccgcgtt ctggggcaac ttcgactacg
    14521 agaagtcgat caaggccggc atggactacg ccgggctgcc ctatagcggc aagttcgact
    14581 tcatcgagac gcggatgaac tggttcatca cgcacatggt ggcgcccaag gaagacgcgc
    14641 tgaagtgcaa tgattgccac acccgctcgg aagacggccg cctggccgcg atcaccgaca
    14701 tctacatgcc cggtcgcgac cgcaacggct gggtcgacct cctcggcggg ctggcgatca
    14761 tcggtgcgat cggcgccggt tcggtccacg gcatcgcccg catcctcacg cgtcgcaagg
    14821 ggcactgaaa atgagcgcga accgcatcta catctacaag cgctatgagc gcttctggca
    14881 ctggtcgcag gcgctgctga tcatcatcat gatgatcacg ggcttcgaga tccatggcag
    14941 ctacaccttc ctggggttca agaaggccgt cgatctgcac acgatcgcgg cctggaccct
    15001 gctggtgatc tgggccttca cgatcttctg gcaattcacc acgggtgagt ggaggcagta
    15061 catcccgtcg atgaagaacg tgtcggcgat gatcctctac tacacggtcg ggatcttcaa
    15121 ggagatgccg catcccttcc gcaagaccac ggtgcagaag cacaacccgc tgcaacgcct
    15181 ggcctatctt gcgctgcttg cgttcatctc gccgctgatc tggggctcgg gcctgctcta
    15241 cctgttctac ggcaactggg cgcagctggg gatcgacaag accttctcgc tcgagggcgt
    15301 ggcgctggtg cataccgcgg gcgcgttcat gatcaccgcg ttcttcttca tccacgtcta
    15361 cctgaccacg accggtcaca cgatcttcgc ccacatcaag gcgatgatca ccggctggga
    15421 agaggtcgag gacgaccacg caccggccgc ggccgatcac ggcaagcgcg cacccggcaa
    15481 ggcctgagcg ttcgcgccgc atcgcggcgc cacgatcgga cgaagacgcc ccgcggctgg
    15541 ttcagcgcgg ggcgtcttcg tccgggagtt cgtaatggtc ggcgatgtag gccgggccct
    15601 tcatgacgaa cacgatgaag gcgccgatcg ccacggtgaa taccacggtc cagtgcagga
    15661 tcaccgcggc cagcacccgg atgtcgatca tctgaagcgc gcgcaccgcc tcgatgctgt
    15721 cgtcgctcca ccaatgcagg cgggcaagca gtgagaccgc catgcaggcc gcggtaccga
    15781 cgagcgccac catgggcagg cgcgccagaa ccttgcgttc gagtcctgcc ggttcggtgc
    15841 gcgagccggg caggcggcgc cagcgcttct ccatgatgat tctccgatgt cttgccgttg
    15901 cggcctggct gccgagagcc gggtggcgct gctgcttcga cccgatccga ttctccggcg
    15961 tccgctgcga ttcgtggcag aaaagcacca cgcccggcgg tggcccctcg gaccgggggt
    16021 agaatgccgg caccgcacct gcgtcgcaca gcttgcggca ccgctccgga agtcaggctt
    16081 ccggagtgct gatcagacac cgacccgcgt tccagagttc tacccgaaat gacccttcag
    16141 caagccgaaa ccgccgcccc cgagcccgcc agcaccgaag cgccggaggc agccaagcag
    16201 ccgcgcatcg agccgcgtgc gatcctgaaa cgcctgcagg ccgaatcgcc cgcctttcgg
    16261 gacagcaagc cgctggcgct gaagatcgac gcgagcatcc tcgcccgctt tcccgatttc
    16321 gatcgcaaga acctgcgtat cgccctgcgc atgcacaccg cctcgaccaa gtacctcaag
    16381 gcggtcgagc gtggcggcga gcgcttcgac ctcgacggca aagcagccgg cgaggtgacc
    16441 gaggagcaac gccagcacgc cgccgccacg ctgaaggagc gctttgccgc ggtggccaag
    16501 cagcagcgcg agaagcgcga ggccgaggaa gccgaacgca gacgcgccga aaaactccag
    16561 caactggtga gcaagttcgg gcgctgagcc tgcgaggaca ccctcgggct cagcgcaggt
    16621 cgcgccgcac cgagtcggcc cgcgccatcc agatccccgc cgcggccgcg atcgccaccg
    16681 cgagcgcccc gcccgggtgc ccggtcccga tcatcaggcc ggcgagcagg ccgagggtga
    16741 gcagcgctcg gaaagtgatg gtttgcatgg tggtctcccg atcttttttc actgtacgaa
    16801 gactgtatat atgaacagta ttcggcgcaa gtccacgcgc acggaaacac tgcgtgcgcg
    16861 tgcgatccga cgcgatggcg ggcaggcgtc ttgcgctata atccgcagcg ccttgccggc
    16921 atagctcagt tggtagagca gctgatttgt aatcagaagg tcgtgggttc gattcctatt
    16981 gccggcacca gaattcttcc ggcgcttgtg cggcgcagaa agttcttgcc tttccgccgc
    17041 tcaacgttta tagttctgtt tctccgacgc ggggtggagc agtctggcag ctcgtcgggc
    17101 tcataacccg aaggtcgcag gttcaaatcc tgcccccgc
//
LOCUS       DAOTIN010000069        16930 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_4082_length_16930_cov_8.936533, whole genome shotgun sequence.
ACCESSION   DAOTIN010000069 DAOTIN010000000
VERSION     DAOTIN010000069.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 16930)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 16930)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16930
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4082_length_16930_cov_8.936533"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            199..1275
                     /locus_tag="P5537_11020"
     CDS             199..1275
                     /locus_tag="P5537_11020"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HRV78614.1"
                     /translation="MPTQTENLNVLAFDHMPSPDEVKARVPLTERAAAAVIAGRKAVM
                     DILDRKDPRVFVVVGPCSIHDPVAGLDYARRLKALADEVSDVLLLVMRVYFEKPRTST
                     GWKGYINDPFMDDSFRIDVGMERARKFLLDVCELGLPTATEALDPIAPQYYGDLIAWT
                     AIGARTSESQTHREMASGLSTPVGFKNATDGDLEVAINAILSAGSPHSFLGINSQGQS
                     AVTRTRGNRYGHVVLRGGGGRPNYDTVSVSLAEQALAKARLAKNIVVDCSHANSWKKP
                     EYQPLVMKDVMHQIREGNQSIVGLMIESNLEAGNQPIPADLSQLKYGCSVTDACVDWA
                     TTEDMIRKSAAVLREVLPKQERRA"
     gene            1272..2114
                     /gene="serB"
                     /locus_tag="P5537_11025"
     CDS             1272..2114
                     /gene="serB"
                     /locus_tag="P5537_11025"
                     /EC_number="3.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036424 - L-phosphoserine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006564 - L-serine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase SerB"
                     /protein_id="HRV78615.1"
                     /translation="MNLVVLAEDVDSVALKNVAKVTEANAIEQITTRSFRLVGAKPAE
                     GLVAACTAGGLDHVWLPEGRQLSDFGLFVTDMDSTLINIECIDEIADMQGLKGEVAAI
                     TEAAMQGEIDFRESLTRRVALLAGLPESALAEVFDHRLQLNPGAERLLQGLQRAGIRT
                     MLVSGGFTYFTERLKSRLGFDHAWANELEVYDGKLTGKVIGDIVDGEAKAAHLERTRD
                     ELGLKPEQVIAAGDGANDIPMLRAAGFGVAFHAKPVLRDVAHCCLDHTGLDGILDLFG
                     PSGA"
     gene            complement(2495..3217)
                     /locus_tag="P5537_11030"
     CDS             complement(2495..3217)
                     /locus_tag="P5537_11030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018989852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV78616.1"
                     /translation="MKRKGIELSNPVIEVDDLCKQVTLADGQGELQILQDIRFAVGAG
                     ESVAIVGASGSGKSTLLGLLAGLDVPARGTVRVQGRDLFALDEDARAALRGEAIGFVF
                     QSFQLLPALTALENVMLPLELAGVDDARAIATQWLQRVGLGSRLTHYPKHLSGGEQQR
                     VALARAFAPDPRVLLADEPTGNLDAETGRAIIELMFALNREQGTTLILVTHDESLARR
                     CSRVLRMEAGRLSEAESAVAPL"
     gene            3201..3836
                     /locus_tag="P5537_11035"
     CDS             3201..3836
                     /locus_tag="P5537_11035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylesterase"
                     /protein_id="HRV78617.1"
                     /translation="MPLRFIIPFVFLFFFSALARADTILVWGDSLSAGYGLDQGQEWP
                     ALLQTRLQAEGFRHVVVNASVSGETSSGGRTRLPAALAEHSPRLVILELGANDGLRGL
                     KPQLLADNLGAMIDAAHEAGARVLLVGMRMPPNYGPAYTRRFAEVFADVAEAKKVPLV
                     PFLLDGFADRPELFLPDGIHPTAEAQPRIVDTVWAGLHPLLASEGKKSARR"
     assembly_gap    3905..4004
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(4285..5325)
                     /gene="selD"
                     /locus_tag="P5537_11040"
     CDS             complement(4285..5325)
                     /gene="selD"
                     /locus_tag="P5537_11040"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018989854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004756 - selenide, water dikinase
                     activity [Evidence IEA];
                     GO_process: GO:0016260 - selenocysteine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HRV78618.1"
                     /translation="MNEIRLTEFSHGGGCGCKIAPAVLSELLATMPAGLVPPELLVGT
                     DTADDAAVYKLNDRQAIVATTDFFTPIVDNPRDFGRIAATNALSDVYAMGAQPILALA
                     IVGMPLDKLPPEVIGEILKGGAEVCRDAGIPIAGGHSIDVLEPIYGLVGLGVVDPARV
                     RTNAGAKSGDVLILTKPLGIGILSAGLKKGRLSEDGYAQMIRWTTTLNRVGARLADIE
                     GVHAVTDVTGFGLAGHLLEMCRGASLTGAVRFDALPVIEEARALVQDGVATGASTRNW
                     ASYGASVELAADGPEWQRKLVTDPQTSGGLLIACAPEAVEAVQAAVRAEQGEAGTIIG
                     EMRSGPARVVVD"
     gene            5384..6436
                     /gene="mnmH"
                     /locus_tag="P5537_11045"
     CDS             5384..6436
                     /gene="mnmH"
                     /locus_tag="P5537_11045"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043828 - tRNA 2-selenouridine synthase
                     activity [Evidence IEA];
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HRV78619.1"
                     /translation="MQKGVATVAQLSGFDEIIDARTPAEFAEDHIPGAINLPVLDNDE
                     RIVVGTLYKQQSAFDARRLGGALVAANISRHMLAMLQDKPKNWRPLIYCWRGGQRSGS
                     FTTWLRMVGWDACQLEGGYKAFRHHVIAEIERIVPTLTLRIVCGPTGSAKTRVLEALA
                     AQGAQVLDLEDLAAHKGSVLGALPDRPQPAQKRFETLLWDRLRRLDPARPVYVEAESR
                     KIGLVFVPEPLILAMRRARCVLIDATREARLAFLVRDYAYLGDDVGALQDKLHRLREH
                     QSRETLERWKSLAAAHALPELFAELIDQHYDPLYHRSQNHNYVNYGDALRVASADLGE
                     AGVRELAARILAEGAG"
     gene            complement(6546..7130)
                     /locus_tag="P5537_11050"
     CDS             complement(6546..7130)
                     /locus_tag="P5537_11050"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HRV78620.1"
                     /translation="MPFKHSPDPRLGAAAHPGGSAPSEWVRRFAALLPEGARVLDLAA
                     GGGRHARWLAGRGCKVMAVDRDAAALATMQGVAGVETRVLDLEGPDWPLGGQQFDAVV
                     VANYLYRPRFAELFELVRPGGLLIYETFMLGNERFGKPSNPDFLLRPCELLACLPEGW
                     SVVAFEQGEVGRPAMIQRLCASRSAVPGRLPSLI"
     gene            7498..9114
                     /locus_tag="P5537_11055"
     CDS             7498..9114
                     /locus_tag="P5537_11055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HRV78621.1"
                     /translation="MSPIVPPNLLRQRRLETWLGAGFALAAPAARGAEVALVEPLSAA
                     ALPIGAALIGGLVIGVGLGHFLGRRATREHGDGRTAGTAHASSTRGAATLGPAADART
                     VAPAGELADATQPVTRMPGAVPGFLGADAPTGLARAAPARAEHGHAAEDAPADATPPP
                     AGSSAHPNGVAADSYREVVDSLSEVLFRTDELGRLVFLNDAWKDLSGFELDSARLHPL
                     GDFLHPDDRMRARDAIRALLAGDAQEWTDELRLRTLAGEIRWVGITCRALRDGSGRES
                     GIAGTIDDISARKIAEFSLRNLNQELESRVRSRTAELETAMRELEAFSYSVSHDLRAP
                     LRAIDGFARILAEEAGPQLEERHRDQLVRIRAGAERMAILIDALIDLASVSRQPLRRQ
                     PVDLSRIAEGVIRDLQAESPGRAVAVEITRDMTVIADPVLMHVLLDNLLRNAWKFTSH
                     CEHPRIVFGAAREGDRAVFHVEDNGAGFDMNYAGKLFQPFQRLHAQHEFPGTGIGLAT
                     VQRIVARHEGRVWASAEPGKGARFCFMLGH"
     gene            9312..11999
                     /locus_tag="P5537_11060"
     CDS             9312..11999
                     /locus_tag="P5537_11060"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004318240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HRV78622.1"
                     /translation="MKEKHYLTPLLEPRSVGIIGASEREASLGSVLMRNMLEAGYKGK
                     LFAINPKHEKVHGVACYKSVEDVPQRLDLVVMAVRAEKTPALMEACGRAGVKAVILLS
                     GGFSESGARGALLERQVIEAAHRHRIRLLGPNCLGIMRPQLGVNATFAHASALKGSIG
                     LISQSGALCAAILDWAKPNNVGFSTVVSLGSSSDIDFGEVLEYMISDPRTESIFLYVE
                     GIRDARRFMSALRGAARVKPVLLVKAGRHPGASRAILSHSGAPMGEDAVFDAALRRAG
                     VIRLYNMGQLFAAANALFSHFRPRGNRLAIITNGGGPGVMAADRAADIGIPLAEFSEG
                     TIEKLNACLPTGWSHGNPVDILGDAGPERYRAALKAVLEGPNVDGVLVMLTPQAVTDP
                     SGVADVVVELEKTADKPVLVCWMGEELVADARAKFSAAGIPHFRTPEPAVELFSHISA
                     YYQNQKLLMQTPSSLSHLSPPSIESARLVIEMALSERRKKLNEMESKALLAAFRIPIA
                     QTVVARTAAEAMVLSAEIGLPVVMKIDSPNIVHKSEVGGVRLNIRSLAAVRSTYQEIL
                     DEVKRVQPEAVINGIAIEPMIQKRNGRELVVSVRRDPVFGPAITFGEGGNLVEENRDV
                     AVALPPLNSFLVKDMIRSTRISTRLGEFRNMPAVDMNALELVLLRISEMVCELPWITA
                     MEINPLIVDENGVVAVDANISVDNVSPTADRYDHMAIHPYPSHLISTWTVPDGTTVTI
                     RPIKPEDAELEVDFVRRLSAETKYYRFMNTMRELPPAMVARLTQIDYDREMAFVATLE
                     VDGVENEIGVCRYAVNPDGESCEFAVVVADDWQHRGLARKLMGVLIETARSRGIQYMN
                     GVFLANNERMLKFVQRLGFVLSNDPEDSSVKLGILSLQD"
     gene            12003..12851
                     /locus_tag="P5537_11065"
     CDS             12003..12851
                     /locus_tag="P5537_11065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-hexose-6-phosphate mutarotase"
                     /protein_id="HRV78623.1"
                     /translation="MPATIEHIDFHGQPALRLATASGARAVVALQGAQVLSWTPPGGE
                     ERLYLSPQAVFDGRTAVRGGIPVCFPQFADLGPLPAHGFARNRRWTLATERSGKDFAL
                     VGLQLADDEASRALWPHAFTAELSILIEDSRLDLELEIANTGDEAFEFTAALHTYLAV
                     REVEESRIEGLHGFSYRDKTDANRIQRDSGDALVIEAETDRVYHEVSRPLLLREYDRS
                     LGINADGFPDVVVWNPWVERSAAIADLPDDGFRRMLCIEAAAARQPVRVQAGESWWGR
                     QTLVAL"
     gene            complement(12922..14013)
                     /locus_tag="P5537_11070"
     CDS             complement(12922..14013)
                     /locus_tag="P5537_11070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004373499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carotenoid 1,2-hydratase"
                     /protein_id="HRV78624.1"
                     /translation="MAWLLLVGGGMAQAQESGPPYPPVLPGKALLFPQDFGAHPDYRT
                     EWWYITGWLRDAAGVERGFQLTFFRVRTRIGEDNPSRFAPRQLVLAHAAVADPASGRL
                     RHAERSGRAYPGLVEALEGRTAVRVDDWFLAGGDSTQAGYRSRIEAEDFGFELDFTPD
                     RPPVINGREGYSQKAPDPLNASYYYSRPQLAVRGTLRLDGEPVAVSGHAWLDHEWSSE
                     ILPAEARGWDWIGINLADGGGLMAFRMRDHDGRALWAAASTSARDGSVRIHPPAEVRF
                     EPLRHWRSPRTGIEYPVEWAVTVAERRFRLSPLMDDQELDSRASTGAIYWEGAVRLYE
                     AGEGAEAEVGGEVGRGYLEMTGYAERLRM"
     gene            complement(14126..16681)
                     /locus_tag="P5537_11075"
     CDS             complement(14126..16681)
                     /locus_tag="P5537_11075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV78625.1"
                     /translation="MSVPLRRLFLASLLRRRLASALSLLAIALGVALGLAVHLIHGAA
                     LDEFGRGMRAVAGKADLQVVGARDGFDEGLFVTLARRPEVAAASPVLEIEARLPGREE
                     SLRILGVDLFRVLRVQPGLMPLADGDGDDLRFAALRPGVVFLSEDAHQRLSSPGRSAA
                     GEALPPALADARIAVQSGVRSLVLEAGGRVPGASGVLGVMDLGAAQQAFGRIGVLSRI
                     DLRLAEGVSPSAAQAALSALLPPGIALRAPEAAAGELGSLSRAYRVNLTMLAAIALLT
                     GGFLVFSTQLLSVARRRREFALLRALGLVRAELMRGLLAEGAAVGVVGGVLGVALGHA
                     LAAGAFRLVGGDLGAGFFRGVAPQLAFDPAASLAYLLLGVLAGIAGTWLPARAAAAVA
                     PARALRAGEGERAGLTRGDGRGRLAAAMLVLAVLACLVPPLGGIPVGGYAAVVFVLAA
                     AILALPVLARFVLPLLARGRSATWRLAHARLAAAPGQAVVAGAGVIASVALAVSMAIM
                     VNSFRVSVDEWLAQVLPADLYVRASVASGSGYLDPQALAAIAATPGVARVDTTRLINL
                     RLSDAEPLFSVLARPAQGNWGLPLVSGSMEPVVGDAESLPPAWVSEAAADRHDLSRGS
                     RFELPLGGRMQAFRVAGVWRDYARQHGAALIESRDYVALTGDDRVNDAALLLAPGATS
                     AAVAQALRERFGAEHITIALPGEIRAISLQIFDRTFLITYLMEAVAVVIGLFGIATTF
                     AALAATRQGEFGMLRHLGFTRAEIGRLIATEGALTAGLGVVAGLAGGAAIAWVLIEII
                     NRQSFHWSMELAVPWSGLTIFAVSLVMLAALVARLAGRHAMRQSAVLAVKADW"
     gene            complement(16761..>16930)
                     /locus_tag="P5537_11080"
     CDS             complement(16761..>16930)
                     /locus_tag="P5537_11080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV78626.1"
                     /translation="LDPGRASEVLDLLLGQIRDSRAAGVMVTHSRSAAARADRVLELR
                     ADGLHDITERT"
BASE COUNT         2592 a         6249 c         5732 g         2257 t
ORIGIN      
        1 ctccggcccc ccggtcttcg aggacagcgc cttcgacgta ggggccgatc cggcctccat
       61 cagcatcgcc atccgatact gagcctgcac gccgcggccc tgggccttca cccggccgcg
      121 gcgcaaatct ccgcggacac accccgacac gggcgttaca attgcaggct ttcaaggcag
      181 caaccggagt cgcctgcaat gcccacccag accgaaaacc tcaacgtcct cgccttcgac
      241 cacatgccct cgccggacga ggtgaaggcg cgtgtgccgc tgaccgagcg tgccgcagcc
      301 gcggtgatcg ccgggcgcaa ggcggtgatg gacatcctcg accgcaagga tccgcgcgtg
      361 ttcgtggtgg tcgggccgtg ctcgatccat gacccggtgg ccgggctgga ctatgcgcgg
      421 cggctgaagg cgctcgccga cgaggtctcc gacgtgctgc tgctggtgat gcgggtgtat
      481 ttcgagaagc cgcgcacctc gaccggctgg aagggctaca tcaacgaccc cttcatggac
      541 gactccttcc gcatcgacgt cggcatggag cgcgcgcgca agttcctcct cgacgtgtgc
      601 gagctcggcc tgcccaccgc caccgaggcg ctcgacccga tcgcgccgca gtactacggc
      661 gacctcatcg cctggaccgc gatcggcgcg cgcacctccg aatcgcagac ccaccgtgag
      721 atggcctcgg gcctgtcgac gccggtcggc ttcaagaacg ccaccgacgg cgatctcgag
      781 gtggcgatca acgcgatcct ctcggcgggc agcccgcaca gcttcctcgg catcaacagt
      841 cagggccagt cggcggtcac gcgcacccgc ggcaaccgct acggccacgt ggtgctgcgc
      901 ggcggcggcg gccgtcccaa ctacgacacc gtgtcggtgt cgctggccga gcaggcgctc
      961 gcgaaggcca ggctggcgaa gaacatcgtg gtcgactgct cgcatgccaa ctcgtggaag
     1021 aagcccgagt accagccgct ggtgatgaag gacgtcatgc accagatccg cgagggcaac
     1081 cagtcgatcg tcggcctgat gatcgagagc aacctcgagg ccggcaacca gccgatcccc
     1141 gccgacctgt cgcagctcaa gtacggctgc tcggtcaccg acgcctgcgt cgactgggcg
     1201 accaccgagg acatgatccg aaagtcggcc gccgtgctgc gcgaggtgct gcccaagcag
     1261 gagcggcgcg catgaacctg gtcgtgctgg ccgaggacgt cgacagcgtc gcgctcaaga
     1321 acgtcgccaa ggtcaccgag gcgaacgcga tcgagcagat caccacgcgc tccttccgcc
     1381 tcgtcggcgc gaagcctgcc gaaggcctgg tggcggcgtg cacggccggc gggctcgatc
     1441 acgtttggct ccccgaaggt cgccagctga gcgacttcgg gctcttcgtc accgacatgg
     1501 actcgacgct gatcaacatc gagtgcatcg acgagatcgc cgacatgcag ggcctcaagg
     1561 gcgaggtcgc ggcgatcacc gaagcggcga tgcagggcga gatcgatttc cgcgagtcgc
     1621 tgacgcggcg cgtggcactg ctcgccggcc tgcccgagag cgcgctcgcc gaggtcttcg
     1681 atcaccgcct gcagctcaac ccgggggccg aacgcctgct gcagggcctg cagcgcgcgg
     1741 gcatccggac gatgctggtg tcgggcggct tcacctactt caccgaacgg ctcaagtcgc
     1801 ggctcggctt cgaccatgcg tgggcgaacg agctcgaggt gtatgacggc aagctcaccg
     1861 gcaaggtgat cggcgacatc gtggacggcg aggccaaggc cgcgcacctc gagcgcacgc
     1921 gcgacgagct cggcctcaag cccgagcagg tgatcgccgc cggcgacggc gccaacgaca
     1981 tccccatgct gcgcgccgcc ggcttcggcg tcgccttcca cgccaagccc gtactgcgcg
     2041 acgtcgccca ctgctgcctc gaccacaccg ggctcgacgg catcctcgac ctgttcggcc
     2101 cgagcggcgc gtaagcagcg ctccacgttt ccatccgcac ttaggcggcg ccccaccttc
     2161 ccatccgcgc cttccggcgc tcctgcgccg aggagatggt cggcgccccg gaaggcgcaa
     2221 acacgggcag cagcatcgtc ggccacgacg gacgccgcac cccgtgctcc cccgctaccc
     2281 ccctgcagga gcgccggaag acgcgaatgg ggccgtccgg cgccgtcgtt cgcgtcgaat
     2341 gcagcgccac cctcttcgcg gctgccgccg cttcgaagac atggcgatta ccgggccgcc
     2401 gccctgtagg agcgccggaa ggcgcgaatg gggccgtccg gctccgtcgt tcgcgtcgaa
     2461 tgccgcaatg ccctcttcgc ggctgccgcc gctcctacag cggggcgacc gcgctctccg
     2521 cctcgctcaa gcgccctgcc tccatcctca gcacgcggct gcagcggcgg gcgagcgact
     2581 catcgtgggt gaccaggatc agcgtggtgc cctgctcgcg gttgagcgcg aacatcagct
     2641 cgatgatcgc cctgcccgtc tcggcatcca ggttgccggt gggctcgtcg gcgagcagca
     2701 cccgcgggtc gggcgcgaag gcgcgcgcga gcgcgacccg ctgctgctca ccgcccgaca
     2761 gatgcttggg ataatgcgtg agccgactgc ccagccccac gcgctgcagc cactgcgtgg
     2821 cgatcgcgcg cgcgtcgtcc acgccggcga gctccagcgg cagcatcacg ttctccagcg
     2881 cggtgagcgc cggcagcagc tggaaggact ggaacacgaa gccgatcgcc tctccgcgca
     2941 gcgccgcacg cgcgtcctcg tcgagcgcga agaggtcgcg cccctgcacc cgcaccgtgc
     3001 cgcgcgcggg aacgtccagc ccggcgagca atcccagcag ggtcgatttg ccagagccgg
     3061 acgcgccgac gatcgccacc gactcgcctg cgcccacggc aaagcggatg tcctgcagaa
     3121 tctgcagctc gccctggccg tcggccagcg tgacctgctt gcacaggtca tcgacctcga
     3181 tgaccggatt ggagagctcg atgcccttgc gtttcatcat tcccttcgtc ttcctgttct
     3241 tcttttccgc cctcgcccgc gccgacacga tcctcgtctg gggcgacagc ctgtcggccg
     3301 gctacggcct ggatcagggc caggagtggc ccgccttgtt gcagacgcgt ctgcaggccg
     3361 aagggttccg ccatgtcgtc gtcaacgcga gtgtatccgg tgagacctcg tcgggtggcc
     3421 gcacccgact gcccgccgcg ctcgccgaac attcccccag gctggtgatc ctggagctcg
     3481 gcgccaacga tggcctgcgc ggcctcaagc cgcaactgct cgcggacaac ctgggcgcga
     3541 tgatcgacgc cgcgcacgag gcaggcgcac gcgtgctgct cgtgggcatg cgcatgccgc
     3601 ccaactacgg cccggcctac acgcggcgct tcgccgaggt cttcgccgac gtggcggagg
     3661 cgaagaaggt gccgctcgtg cccttcctgc tggacggctt cgccgaccgg cccgagctct
     3721 tcctgcccga cggcatccac cccaccgccg aggcgcagcc gcgcatcgtc gacaccgtat
     3781 gggccggcct gcacccgctg ctggccagcg aaggaaagaa gtcggcgcgc agatgaagcg
     3841 cgcaccgcgt cttgtagccg gcaggcgcga attcggcggc gagggtcggc acgcgcgtcg
     3901 gctgnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnncggcac cgcccgttcg
     4021 cggctgccgc cgctcctaca gggggtccgg gatgcgcggc ggtttccgta ggagcgccgg
     4081 caggcgcgaa ttcggcggcg agggtcggca cgcgcgtcgg ctgcggcacc gcccgttcgc
     4141 ggctgccgcc gctcctacag ggggtccggg atgcgcggtg gtttctgtag gagcgccggc
     4201 aggcgcgaat gcggcggcga ggatcggcac gcgcgtcgat tgcgggaccg cccgttcgcg
     4261 gctgccgccg ctcctacagg ggcatcagtc gacgacgacg cgggcgggcc ccgagcgcat
     4321 ctcgccgatg atcgtcccgg cctcgccctg ttcggcgcgc accgcagcct gcacggcctc
     4381 gacggcctcc ggcgcgcagg cgatgagcag gccgcccgag gtctgcggat cggtgacgag
     4441 cttgcgctgc cactccggcc catccgccgc cagttccacg ctcgccccat agctcgccca
     4501 gttgcgcgtc gatgcgcccg tggcgacgcc gtcctgaacc agggcgcgcg cctcctcgat
     4561 caccggcagt gcatcgaacc gcaccgctcc ggtcagcgac gcgccgcggc acatctcgag
     4621 caggtggccg gcgaggccga agccggtgac gtcggtgacc gcgtgcacgc cctcgatgtc
     4681 ggcgagcctg gcgccgacgc gattgagcgt ggtggtccag cggatcatct gcgcatagcc
     4741 atcctccgac agccggccct tcttgaggcc cgccgaaagg atgccgatgc cgagcggctt
     4801 ggtcaggatc agcacgtcgc ccgacttggc acccgcgttg gtgcgcaccc gggccgggtc
     4861 gaccacgccg agcccgacca ggccgtagat cggctcgagc acgtcgatcg agtgaccgcc
     4921 tgcgatcggg atgcccgcgt cgcggcagac ctcggcgccg cccttgagga tctcgccgat
     4981 gacctccggc ggcagcttgt cgagcggcat gccgacgatc gccagcgcca ggatgggctg
     5041 ggcgcccatc gcatagacgt cggagagcgc gttggtggcg gcgatgcggc cgaagtcgcg
     5101 cgggttgtcg acgatcgggg tgaagaagtc ggtggtggcg acgatggcct ggcgatcgtt
     5161 gagcttgtac accgcggcgt cgtcggcggt gtcggttcct accagcaact cgggcgggac
     5221 aaggccggcc ggcatggtcg cgagcagctc ggagagcacg gcgggggcga ttttgcagcc
     5281 gcagccgccg ccgtgggaga attcggtcag tctgatttcg ttcatgtttc cgagggagaa
     5341 agcgacgcgc ggcgcaagaa gcgccgcgcg gcgtatcaac actatgcaaa aaggcgtcgc
     5401 gaccgtagca cagctgtccg gctttgacga gatcatcgac gcgcgcacgc ccgccgagtt
     5461 cgccgaggac cacatccccg gcgcgatcaa cctgccggtg ctcgacaacg acgagcgcat
     5521 cgtcgtcggc accctgtaca agcagcagtc cgccttcgac gcccgccgtc tcggcggcgc
     5581 gctggtcgcc gccaacatct cgcgccacat gctcgccatg ctgcaggaca agcccaagaa
     5641 ctggcgcccg ctgatctact gctggcgtgg cggccagcgc agcggctcgt tcaccacctg
     5701 gctgcgcatg gtgggctggg acgcctgcca gctcgagggc ggctacaagg ccttccgcca
     5761 ccacgtcatc gccgagatcg agcgcatcgt gcccacgctc acgctgcgca tcgtctgcgg
     5821 tcccaccggc agcgccaaga cgcgcgtgct cgaggcgctc gcggcgcagg gcgcgcaggt
     5881 gctcgacctg gaggacctcg ccgcgcacaa gggctcggtg ctgggcgccc tgcccgaccg
     5941 cccgcagccg gcgcagaagc gcttcgagac cttgctgtgg gaccgcctgc gtcgcctcga
     6001 tcctgcacgt ccggtgtatg tcgaggccga gagccgcaag atcggcctcg tcttcgtgcc
     6061 cgagccgctg atcctggcga tgcggcgcgc acgctgcgtc ctcatcgatg cgacacgcga
     6121 ggcacggctg gccttcctgg tgcgcgacta cgcctatctc ggcgacgacg ttggcgcgct
     6181 gcaggacaag ctccaccgcc tgcgcgaaca ccagagccgc gagacgctag agcgctggaa
     6241 gtcgctcgcc gccgcccacg ccctgcccga gctcttcgcc gagctgatcg accagcacta
     6301 cgacccgctc taccatcgct cgcagaatca caactatgtg aactatggcg acgcactgcg
     6361 ggtggccagc gcggacctcg gcgaggccgg ggtgcgcgaa ctcgcagcgc gcatcctggc
     6421 agagggggcg gggtaaggct ttgccgaggc cgacaacgcc gcctccacca agttcacaac
     6481 cgtgcctggc cgggcaggaa ccccgcgagg cgcgaatgca gcggtgaaga ggcgtcaggc
     6541 cgaggctaga tcaggctcgg caggcgtccc ggtactgcgc tgcgggacgc gcacaggcgc
     6601 tggatcatgg ccggacgccc gacctcgccc tgctcgaagg cgacgacgct ccagccctcg
     6661 ggcaggcagg ccagaagctc gcacggccgc agcaggaagt cggggttcga aggcttgccg
     6721 aagcgctcgt tgccgagcat gaaggtctcg tagatcagca gcccgcccgg acgcaccagc
     6781 tcgaaaagct cggcgaagcg cggccggtaa agatagttgg cgaccaccac cgcgtcgaac
     6841 tgctggccgc cgagcggcca gtccgggcct tcgagatcga gcacccgcgt ctcgaccccg
     6901 gcgactccct gcatcgtcgc gagcgccgcg gcgtcgcggt ccaccgccat caccttgcag
     6961 ccgcgccccg cgagccagcg cgcatgccgc ccgccgcccg cggcgaggtc gagcacgcgc
     7021 gcaccctccg gcaacaacgc ggcaaagcgc cgcacccact ccgaaggggc actgccgccg
     7081 ggatgggcgg cggcgccaag gcgagggtcg ggggagtgct tgaagggcat tcgtattcct
     7141 tgggatgggt tatgcggccg gccggatttc gacacggtca cgatttcgcc gcagatcgac
     7201 cgcagcgccg cgggaacaga gcggctcccg gggcgactca tgggcgcggt cgaaccggcg
     7261 gatgccgagg ccgtcattct agcggtgcgg agggctcgac acggggcgtc cgcagaagcg
     7321 gccccgcccg cacgagggag tgcgcgttcg ccggcaggca cgctcccatg gcgccttcat
     7381 gccagttgcc ggcgatccgg cgcgtcacca cctacccgcg gcgggttctg tgctatacaa
     7441 ggcaggtccg acagccagga aaaccgtgcg gcctgcgcga tcgccgccac tgacgaggtg
     7501 agccccatcg tcccgcccaa cctgctccgc cagcgccgac tcgagacatg gctcggggcg
     7561 ggcttcgcgc tggccgcgcc ggccgcgcgt ggcgcggagg tcgcgctggt cgagcctctt
     7621 tcggccgcgg cgctgccgat cggcgcggcg ctgatcggcg gcctggtgat cggggtcggg
     7681 ctgggccatt tcctcgggcg ccgcgcaacc cgcgaacacg gcgacggccg gacagccggc
     7741 acggcacacg cctcctccac ccggggcgcc gccaccctgg ggcccgcagc cgacgcgcgc
     7801 accgtggcgc ctgcgggcga gcttgcggat gcgacccagc ccgtgacccg catgccgggc
     7861 gccgtgcccg ggtttctcgg cgccgatgcg cccacaggcc tggcccgggc agcgcctgcc
     7921 cgggccgagc atgggcacgc tgccgaggac gcacccgcgg acgcaactcc accaccggcc
     7981 gggtcctccg cccacccgaa tggcgtggcc gccgactcct accgcgaggt ggtggattcg
     8041 ctcagcgagg tgctcttccg caccgacgag ctcggccgcc tcgtcttcct caacgacgcc
     8101 tggaaggatc tctccggctt cgagctcgac tccgcacgcc tgcatcctct gggcgacttc
     8161 cttcaccccg acgaccgcat gcgtgcacgc gatgcgatcc gcgcgctgct ggccggggac
     8221 gcccaggaat ggaccgacga gctgcgcctg cgcacgctcg ccggcgagat ccgctgggtg
     8281 gggatcacct gccgcgcgct gcgcgacggc agtggccggg agagcgggat cgccggcacc
     8341 atcgacgaca tctcggcgcg caagatcgcc gagttcagcc tgcgcaacct gaaccaggaa
     8401 ctcgagtcgc gggtgcgctc acgcaccgcc gagctcgaga ccgcgatgcg cgaactggag
     8461 gccttctcct actccgtgtc gcacgacctg cgcgcgccgc tgcgcgcgat cgacgggttc
     8521 gcacgcatcc tcgccgagga ggccggaccg cagctcgaag agcggcaccg cgaccagctc
     8581 gtacgcatcc gcgccggtgc cgagcgcatg gccatcctga tcgacgcact gatcgacctc
     8641 gccagcgtct cccggcaacc cctgcgccgg cagccggtcg acctgtcacg catcgccgaa
     8701 ggggtgatcc gcgacctgca ggccgagtcg cccggacgcg cggtcgcggt cgagatcacc
     8761 cgcgacatga cggtgatcgc cgacccggtg ctgatgcatg tgctgctcga caacctgcta
     8821 cgcaacgcat ggaagttcac aagccactgc gaacatccgc gcatcgtctt cggcgcggcg
     8881 cgcgagggcg atcgcgcggt gttccacgtc gaggacaacg gcgcaggctt cgacatgaac
     8941 tacgcaggca agctcttcca acccttccag cgcctgcacg cgcagcacga gtttcccggc
     9001 accgggatcg gcctcgccac ggtgcagcgc atcgtcgccc gccacgaggg ccgggtgtgg
     9061 gcgagcgcgg agccgggcaa gggtgcgcgc ttctgcttca tgctggggca ttgaggacgt
     9121 gaaagccgcg cgcccgaaag gacaccccac cgccggcgac acctgccggc cgggcgggac
     9181 acaaatcgaa cgctgcagag acaaaggtct caaccgcccg ttgtgcactg cagtacaatg
     9241 aatccaattc cgcgcgggcc ggacgcccgc caaaccattg cagcacacca ctcgaacccc
     9301 aggtggccaa catgaaagaa aagcactatc tgaccccgct cctcgaaccg cgctcggtcg
     9361 gcatcatcgg cgccagcgaa cgcgaagcct ccctcggcag cgtgctcatg cgcaacatgc
     9421 tcgaggcggg ctacaagggc aagctgttcg cgatcaatcc caagcacgaa aaggtgcacg
     9481 gggttgcctg ctacaagtcg gtcgaagatg tgccgcagcg cctggacctg gtggtgatgg
     9541 ctgtgcgcgc cgagaagacc cctgcgctca tggaggcctg tggccgcgcc ggcgtcaagg
     9601 cggtgatcct gctctccggc ggcttctccg aatccggcgc gcgtggcgcg ctgctcgagc
     9661 gtcaggtgat cgaggcggcc caccgccacc gcatccgcct gctcggcccc aactgcctcg
     9721 gcatcatgcg cccgcagctc ggcgtcaacg ccaccttcgc gcacgccagc gcgctcaagg
     9781 gcagcatcgg cctgatctcg cagtcgggcg cgctgtgcgc ggccatcctc gactgggcca
     9841 agccgaacaa cgtcggcttc tcgaccgtgg tgtcgctggg ttcgtcgtcc gacatcgact
     9901 tcggcgaggt gctcgaatac atgatctcgg acccgcgcac cgagagcatc ttcctctacg
     9961 tcgagggcat ccgtgacgcc cgccgcttca tgagcgcgct gcgcggcgcc gcgcgcgtca
    10021 agccggtgct gctggtcaag gccggccgcc accccggcgc ctcgcgtgcg atcctgtcgc
    10081 acagcggcgc gccgatgggc gaggacgcgg tgttcgacgc cgcgctgcgc cgcgccgggg
    10141 tgatccgcct gtacaacatg ggccagctct tcgccgccgc caacgcgctg ttctcgcact
    10201 tccgcccgcg cggcaaccgt ctcgcgatca tcaccaacgg tggcggcccg ggtgtcatgg
    10261 cggccgaccg cgccgccgac atcggcatcc cgctcgcgga gttctccgag ggcacgatcg
    10321 agaagctcaa cgcctgcctg cccaccggct ggtcgcacgg caacccggtc gacatcctcg
    10381 gtgacgccgg acccgagcgc tacagggccg cgctcaaggc cgtgctcgaa ggccccaacg
    10441 tcgacggcgt gctggtcatg ctgacgccgc aggcggtcac cgacccgagc ggcgtcgccg
    10501 acgtggtggt cgagctcgag aagacggccg acaagccggt gctggtgtgc tggatgggcg
    10561 aggagctcgt cgccgatgcg cgcgccaagt tcagcgccgc gggcatcccg cacttccgca
    10621 cgcccgagcc ggcggtcgaa ctcttcagcc acatctcggc ctactaccag aaccagaagc
    10681 tgctgatgca gacgccgtcc tcgctgtcgc acctgtcgcc gccctcgatc gagagcgcgc
    10741 gcctggtgat cgagatggcc ctgtccgagc gccgcaagaa gctcaacgag atggagtcga
    10801 aggcgttgct ggccgcgttc cgcattccga tcgcgcagac cgtggtcgcg cgcaccgccg
    10861 ccgaggcgat ggtgctgtcg gccgagatcg gcctgccggt cgtcatgaag atcgactcgc
    10921 ccaacatcgt gcacaagtcc gaggtgggcg gcgtgcggct gaacatccgc agcctcgctg
    10981 cggtgcgctc gacctaccag gagatcctcg acgaggtcaa gcgcgtgcag cccgaggcgg
    11041 tcatcaacgg catcgccatc gagccgatga tccagaagcg caacggccgc gagctggtgg
    11101 tgagcgtgcg ccgcgacccg gtgttcggcc ccgcgatcac cttcggcgag ggcggcaacc
    11161 tggtcgagga gaaccgcgac gtcgcggtcg cgctgccgcc gctcaacagc ttcctcgtca
    11221 aggacatgat ccgctcgacc cgcatctcca cccgcctcgg cgagttccgc aacatgccgg
    11281 cggtggacat gaacgcgctc gagctggtgc tgctgcgcat ctccgaaatg gtctgcgagc
    11341 tgccctggat caccgcgatg gagatcaacc cgctgatcgt agacgagaac ggcgtggtgg
    11401 cggtcgacgc caacatcagc gtggacaacg tgtcgccgac ggcggaccgc tacgaccaca
    11461 tggcgatcca cccctacccg tcgcacctca tcagcacgtg gacggtgccc gacggcacca
    11521 cggtgacgat ccgcccgatc aagcccgaag acgccgagct cgaggtcgac ttcgtgcgcc
    11581 gcctgtcggc cgagaccaag tactaccgct tcatgaacac catgcgcgag ctgcctcccg
    11641 cgatggtcgc gcgcctcacg cagatcgact acgaccgcga gatggccttc gtcgccacgc
    11701 tcgaggtcga tggcgtcgag aacgagatcg gcgtgtgccg ctatgcggtg aacccggacg
    11761 gcgagtcctg cgagttcgcg gtggtggtgg ccgacgactg gcagcatcgc gggctcgccc
    11821 gcaagctgat gggcgtgctg atcgagaccg cgcgcagccg aggcatccag tacatgaacg
    11881 gggtcttcct ggccaacaac gagcgcatgc tcaagttcgt gcagaggctc ggtttcgtgc
    11941 tcagcaacga cccggaagac agctcggtca agctgggcat cctgtcgctg caggactgag
    12001 cgatgccggc gacgatcgaa cacatcgatt tccacggcca gcccgcgctg cgcctggcca
    12061 ccgcgtcggg tgcgcgcgcg gtggtcgcgc tgcagggtgc gcaggtgctg tcgtggactc
    12121 cacccggtgg cgaggagcgc ctctacctga gcccgcaggc ggttttcgat ggccgcactg
    12181 cggtgcgtgg cggcatcccg gtgtgtttcc cgcagttcgc cgatctcggc cccctgcccg
    12241 cccatggctt cgcgcgcaac cggcggtgga cgctggcgac cgagcgcagc ggcaaggatt
    12301 tcgcgctggt cggcctgcag ctggccgacg acgaggccag ccgcgcgctg tggccgcatg
    12361 cgttcacggc ggagctgtcg atcctcatcg aggacagccg gctcgacctc gaactcgaga
    12421 tcgccaacac gggcgacgag gccttcgagt tcaccgccgc gctgcacacc tacctcgcgg
    12481 tgcgcgaggt cgaggagtcg cgcatcgagg gcctgcacgg cttctcctac cgcgacaaga
    12541 ccgacgccaa ccgcatccag cgcgacagcg gcgacgcgct ggtgatcgag gccgagaccg
    12601 accgcgtcta ccatgaggtc agccggccgc tgctgctgcg cgagtacgac cgcagcctgg
    12661 gtatcaacgc cgacggcttc cccgacgtcg tggtgtggaa cccctgggtc gagcgcagcg
    12721 ccgcgatcgc cgacctgccc gacgacggct tccgccgcat gctctgcatc gaggccgccg
    12781 ccgcgcgcca gccggtgcgc gtgcaggcgg gcgaatcctg gtggggccgg cagaccctgg
    12841 tcgcgctctg agcgttttct tgcccgatca cggcggagag ggcggacgcg ggaccgcctt
    12901 ctccccgcga acgtccgcgc ctcacatgcg caggcgttcg gcgtaacccg tcatttccag
    12961 gtagccacgg ccgacctccc cgccgacctc cgcctcagcg ccctccccgg cctcgtacag
    13021 gcgcaccgcg ccctcccagt agatggcgcc ggtcgaggcg cggctgtcga gctcctggtc
    13081 gtccatcagc gggctcagcc ggaagcgtcg ctcggccacc gtgaccgccc actccaccgg
    13141 gtactcgatg ccggtgcgcg gcgaacgcca gtggcgcaaa ggctcgaagc gcacctccgc
    13201 gggcgggtgg atgcggacgc tgccgtcgcg cgcgctcgtg ctcgccgcag cccagagcgc
    13261 gcgcccgtcg tggtcgcgca tgcggaaggc catcaggcca ccgccgtcgg cgaggttgat
    13321 gccgatccag tcccagccgc gcgcctccgc gggcaggatc tcgctcgacc attcgtggtc
    13381 cagccaggca tggccgctca ccgccactgg ctcgccgtcc aggcgcagcg tgccgcgcac
    13441 cgcgagctgc ggccggctgt agtaatagct ggcgttgagc gggtcgggcg ccttctggct
    13501 gtagccctcg cggccgttga tcaccggcgg acgatccggg gtgaaatcga gctcgaagcc
    13561 gaagtcctcc gcttcgatgc ggctgcggta tccggcctgc gtgctgtccc cgccggcgag
    13621 gaaccagtcg tccacccgca ccgccgtgcg tccctccagc gcctcgacca ggccgggata
    13681 ggcgcgcccc gagcgctcgg cgtggcgcag ccgcccgctc gccggatcgg ccaccgctgc
    13741 gtgcgcgagc accagctggc gcggcgcgaa gcggctcggg ttgtcctcgc cgatgcgcgt
    13801 gcgcacgcgg aagaaggtga gctggaagcc gcgctccacg ccggctgcgt cgcgcagcca
    13861 gccggtgatg taccaccact cggtgcgata gtcgggatgc gcaccgaaat cctgcggaaa
    13921 cagcagcgcc ttgcccggca gcaccggcgg atagggcggc ccggactcct gcgcctgcgc
    13981 catcccgccc ccgaccagca gcagccaggc catgagcatc acccacagcc ggacaagccc
    14041 cgtgccggtg ccccccggca caatccacgc cgcgcgccgc ccagccctca ccgctcctgc
    14101 ctgctcacgc ctcacgcctc cctccctacc aatccgcctt caccgccagc accgccgact
    14161 gccgcatcgc atgccgcccg gcgagccggg ccaccagcgc agccagcatc accaggctga
    14221 cggcgaagat cgtcaacccg ctccagggca ccgccagctc catgctccag tggaagctct
    14281 ggcggttgat gatctcgatc agcacccagg cgatcgccgc gccgccggcc agccccgcga
    14341 ccacgcccag gcccgcggtg agcgcgccct cggtggcgat caggcggccg atctcggcgc
    14401 gggtgaagcc gaggtggcgc agcatgccga actcgccctg gcgggtggca gcgagcgcgg
    14461 cgaaggtggt ggcgatgccg aacaggccga tcaccaccgc caccgcctcc atcaggtagg
    14521 tgatgaggaa ggtgcggtcg aagatctgca ggctgatcgc gcggatctcg cccggcagcg
    14581 cgatggtgat gtgctcggcg ccgaagcgct cgcgcagcgc ctgtgccacc gccgccgaag
    14641 tggcgccggg cgcgagcagc agcgcagcgt cgttcacccg gtcgtcaccg gtgagggcga
    14701 cgtagtcacg gctctcgatc agcgcggcgc cgtgctggcg ggcgtagtcg cgccacaccc
    14761 cggcgacgcg gaaggcctgc atgcggccgc ccagcggcag ctcgaagcgg ctgccgcgtg
    14821 aaagatcgtg acggtcggcg gccgcctcgg acacccaggc cggcggcagg ctctcggcgt
    14881 cgccgaccac cggctccatc gatccgctca ccagcggcag gccccagttg ccctgcgccg
    14941 gtcgcgccag cacgctgaac agcggctcgg cgtcggacag gcgcaggttg atcaggcgcg
    15001 tggtatccac ccgcgccacc ccgggcgtgg ccgcgatcgc cgcgagcgcc tgcgggtcga
    15061 gatagccgct gccgctcgcc accgaggcgc gcacgtagag gtctgccggg aggacctggg
    15121 cgagccactc atccaccgag acgcggaagg agttcaccat gatcgccatc gacaccgcga
    15181 gcgcgacgct ggcgatcacc cccgctcccg ccaccaccgc ctgccccggc gccgccgcca
    15241 ggcgggcgtg cgccagccgc caggtcgcac tgcgtccgcg tgcgagcaag ggcagcacga
    15301 agcgcgcgag caccggcagc gccaggatgg ccgcggcgag cacgaacacc accgccgcgt
    15361 agccgccgac cgggatgccg ccgagcggtg gcaccaggca ggccagcacc gcgagcacca
    15421 gcatcgccgc cgccagccgc ccgcgcccgt cgccgcgggt caggccggcg cgctcgccct
    15481 cccccgcgcg caaggcgcgc gccggcgcca cggcggccgc agcgcgcgcc ggcagccagg
    15541 tgccggcgat ccccgcaaga acgccgagca gcaggtaggc caggctggcc gcggggtcga
    15601 acgccagctg cggcgccacg ccgcggaaga aaccggcgcc gaggtcgccc cccaccaggc
    15661 ggaaggcccc cgcggcgagc gcgtggccga gcgcgacccc gagcaccccg ccgaccacgc
    15721 ccaccgcggc gccctcggcg agcaggccgc gcatcagctc ggcgcgcacc aggccgagcg
    15781 cgcgcaacag cgcgaactcg cgtcgccgcc gcgccaccga cagcagctgc gtggagaaca
    15841 ccaggaagcc accggtcagc agcgcgatcg ccgccagcat ggtcaggttg acccggtagg
    15901 cgcgcgacag cgacccgagc tcgcccgccg ccgcctccgg cgcccgcagc gcgatccccg
    15961 gcggcaacag ggcggacagg gcggcctgcg ccgcggacgg cgagacgccc tcggccagac
    16021 gcaggtcgat ccggctcaac acgccgatgc gcccgaacgc ctgctgcgcg gcgccgaggt
    16081 ccatgacgcc gagcacgccg ctcgcacccg gcacccgccc gcccgcctcc agcaccaggc
    16141 tgcgcacacc cgactgcacc gcgatgcggg cgtcggcgag cgccgggggc agcgcctcgc
    16201 ccgccgcgga gcgccccggc gaagagaggc gctggtgggc atcttcgctg aggaacacca
    16261 cgcccggccg cagggccgcg aagcgcaggt cgtcgccgtc gccgtccgca agcggcatca
    16321 gcccgggctg cacgcgcagt acgcggaaga ggtccacgcc gaggatgcgc aggctctcct
    16381 cacgccccgg caggcgcgcc tcgatctcca gcaccgggct cgccgcggcc acctccggcc
    16441 ggcgcgccag ggtgacgaag aggccctcgt cgaagccgtc gcgcgctccc accacctgca
    16501 ggtcggcctt gcccgcgacc gcgcgcatgc cgcggccgaa ctcgtcgagc gcggcgccgt
    16561 ggatcaggtg caccgccagc ccgagcgcga cgccgagcgc gatcgccagc agcgacagcg
    16621 cgctggccag gcggcggcgc agcaggctgg cgaggaagag tcggcgcagc ggcacgctca
    16681 ccgggcgcgc cccctggcgc tgcacgggcg accggcccgc gctgcgggaa acggcactgc
    16741 ggcccggctt gcgggcgcga tcatgtgcgc tccgtgatgt cgtgcaggcc gtcggcgcgc
    16801 agttccagca cgcggtcggc gcgcgccgcc gcgctgcgcg agtgggtgac catgaccccg
    16861 gcggcgcggc tgtcgcggat ctggccgagc agcaggtcga gcacctcgct cgcccgcccc
    16921 gggtcgaggt
//
LOCUS       DAOTIN010000070        16791 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_4125_length_16791_cov_9.002390, whole genome shotgun sequence.
ACCESSION   DAOTIN010000070 DAOTIN010000000
VERSION     DAOTIN010000070.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 16791)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 16791)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16791
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4125_length_16791_cov_9.002390"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(151..930)
                     /locus_tag="P5537_11085"
     CDS             complement(151..930)
                     /locus_tag="P5537_11085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HRV78627.1"
                     /translation="MRRVVFNQKGGVGKSTITCNLAAIAAAQGKRTLVVDLDPQGNST
                     QYLLGAGVDGLDATLADFFDQTLNFKLNPRDTAEFVVATPFERLHVMPSHPQLEELQS
                     KLESRYKIYKLRDALEELAQDFDCVFIDTPPALNFFTRSALIAADACLIPFDCDEFSR
                     KALYSLLENVQEIKSDHNRGLEVEGIVVNQFQPRASLPQKVVQELIDEGLPVLQPYLS
                     ASIKIKESHEQAKPMIHLDPKHKLSQEFVALHDTLARKYGT"
     gene            1281..3575
                     /locus_tag="P5537_11090"
     CDS             1281..3575
                     /locus_tag="P5537_11090"
                     /EC_number="1.1.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004470 - malic enzyme activity [Evidence
                     IEA];
                     GO_function: GO:0004471 - malate dehydrogenase
                     (decarboxylating) (NAD+) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HRV78628.1"
                     /translation="MDQDFITAALDYHRSPTRGKISVVPTKGLTNQRDLALAYSPGVA
                     AACDAIVADPAEAFELTSRGNLVAVVTNGTAVLGLGNIGPLASKPVMEGKGCLFKKFA
                     NIDVFDIELAENDPDKLIEIIAALEPTLGGINLEDIKAPECFYIEKKLRERMKIPVFH
                     DDQHGTAIISAAGLVNGLKVVGKNIADVRLVCSGAGAAAIACLDMMVSVGLRRENIYV
                     CDSKGVIYEGREPNMEPTKARYAQKTEGRTLGDVIAGADVFLGLSTAGVLKPEMVAKM
                     ADKPLIFALANPNPEILPADAKAVRPDCIVATGRSDYPNQVNNVLCFPFIFRGALDVG
                     ATTINEEMKLACVKAIAELAEAEASDIVASAYGGQELSFGSEYIIPKPFDPRLIVKIA
                     PAVAKAAMDSGVATKPIADLEAYASSLNAFVYQSGIVMKPVFSAAKAVPLEQKRVIYA
                     EGEDERVLHAVRVVLDEGLAAPILIGRPEVIEMRIKKIGLNLKPGRDFEIVNPESDPR
                     YRELWSDYYALMKRDGVTPDLAKAKIRRDTTLIGVMMLRRGDADALVCGTFGSYDYHL
                     KQVADVIGLAPGAKQFAAMNLLLLTKRMLAITDTYVNESPSAEEVAEIARMAADELRR
                     FGIEPNVALLSHSSFGSSSSASARKMRRACEILRETSPDLNVDGEMHGDAALSEEIRD
                     KLHPDSGLKGEANLLVMPNLDAANISFNLMKVANGDGVSVGPILLGAAKPVHIVTPSA
                     TVRRLVNMTALAVVDAKESRNAGA"
     gene            3709..4926
                     /locus_tag="P5537_11095"
     CDS             3709..4926
                     /locus_tag="P5537_11095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004620 - phospholipase activity [Evidence
                     IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase A"
                     /protein_id="HRV78629.1"
                     /translation="MPKTTSPRALLFAGALALSAPAAQAADWLLASSSPRVVPGQRFE
                     VVVIGEGRAAEWPARLPASIELPGGGPSIAVELVAIGKAAAGAGQRRYFARWPMEVAG
                     VAALALVGRPSARVLLDAGAPAGVAAAPAVPAAVVPAVPVAAAAAPAAVAPMAPVAAA
                     PADAVPVEPSGFGFHEPMYFLIGGRDPVSARFQFSFRYRIFDEQGVVAESIPVASGLY
                     FGFTQTSLWDLQSESKPFRDSSFRPSLFYRFALDDPDKRGSLALSGGYEHESNGQEDM
                     PSRSIDTLFVRADARLRLDEAGTYLGVVPKAWTYLDREDNPDIARYRGHAELGLRLGR
                     DDGWLFSTLIRRGTEGKMGTQYDLSYPIRRSVFSGVGAFVHLQAFKGYGETLLEYDEN
                     KEAQYRIGVSLVR"
     gene            4971..5945
                     /locus_tag="P5537_11100"
     CDS             4971..5945
                     /locus_tag="P5537_11100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004312336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone oxidoreductase"
                     /protein_id="HRV78630.1"
                     /translation="MNHAIRIHRTGGPEVLQWEAVELPPPAAGEVRLRHHAVGLNFID
                     TYHRSGLYPLPLPSGLGMEGAGVVEAVGEGVAGLKVGDRVAYTGGPLDAYSEARNIEA
                     RHLVALPDDLSFEQGAAMMLQGITAQYLLHATYPVKAGETILVHAAAGGVGSILVQWA
                     KLLGATVIGTVGNDDKAQRARALGCDHVIVYSREKFPERVRELTGGAGVAVVYDSVGR
                     DTFLDSVACLRRRGTMVSYGNATGAVAPFDCALLHKAGSVYVTRPGLPDYIASRAELV
                     ERAAALFEVVRSGRVKIEILQRYALKDAAQAHRDLEARKTTGSTILLP"
     gene            complement(5996..7096)
                     /locus_tag="P5537_11105"
     CDS             complement(5996..7096)
                     /locus_tag="P5537_11105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004378133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HRV78631.1"
                     /translation="MIRPVLATALASLALLGCQPREPIRIGFLGGLSHRASDVGEAGR
                     NGVQLALEERNAAGGIHGRPLELLVRDDAQTREIAAKGAAELIEAKVEAIVGPFASAM
                     AAAALPHINRNRVVMVSPTITSMDFYGNDDYLFRINRTTRDNAHDYARRLFAQGQRRV
                     AVAYDLRNRSFTESWFREFEAAFSGLGGKTVAAVTFESRPDADFGEVMRAMLAAEPDG
                     LMFLAAAIDLTRLCQHAKLQAPQLPIAAAEWAASEKLIELGGKALEALVIVQAFDRDD
                     RSARYQAFRSAYFKRFQREPGYSSVLAYDAATVLFDAMQRRTEDETLKQALVRHAPFQ
                     GLQQQIAFDANGDTPRTVYFTQIRDGRYVLLD"
     gene            7385..10273
                     /locus_tag="P5537_11110"
     CDS             7385..10273
                     /locus_tag="P5537_11110"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HRV78632.1"
                     /translation="MRPSTGAQGGARWSIRARLLAIGLTPLLLGFPLIMALLVFWGGS
                     YFDRIVIANARTHLAGNERYLEDVRRQAEERVGQLAESRPMRRLLDEAGPAEEVAAIL
                     ASRAETAGLDFLVIATAEGEVLVGTAGRPHGGRLPRSFTLRQARQGLAAAAFERLDPN
                     QLAAIDPGLPARVRVLTPAGQARPGLGGVEEHGLLLTVAAPIASAAGEVDRVLFGGLA
                     LSGNEALVDRMRDVVFPAGTLPDGTEGQTSLLLDSRRVATTLRLAGGERAVGSFAEPE
                     VLAHVLEQGNIWLARASVLGESMIAGYAPIHDGDGERIGMLFSGFPEAPYQREKLQLF
                     AAVGGLFLLLTLLLSGLYVGWSRRITAPLTRIMGTMSAAAAGDLSARVGAPERDDEVG
                     RLGRQLDTMLDALTSETTRREALFDNMRDGLVLIDANGAVRDCNRQFAAMLGYTREEA
                     RGLHVWEWDRSIERPALMDMLQRTDALQNLFETLQERKDGSRFIAEVSSSRVEWGGDS
                     YVLAMQRDIGARKQVEAELERHREHLEAMVRERTAALAEARDQAEAASRAKSAFLANM
                     SHEIRTPMNAIIGLSELLLREGSDGRSSDRLGKIQGAAHHLLGIIDDILDLSKIEAGK
                     LGIERAEFVLSDLVGRAVALVRERAGDKGLRLRSEIDPVLPRALAGDPVRLTQILVNF
                     LSNAVKFADTGDIVVRARQVAAEGGMVHLRLEVVDQGIGIDPAEQLRIFKAFEQADGS
                     VTKKYGGTGLGLAISKRLATLMGGEIGVESAPGQGSTFWIRVPLAVVQPSVQPLASAA
                     AAPAAVPAASSAHQLLRETRAGRRILLVEDHRINQEVAKALLRRAGLVVEVAENGRIG
                     LDRVREHDYDLVLMDISMPVMDGLEATRAIRTLPGRGADVLPVLAMTANAFEDDREAC
                     LAAGMNDHIAKPVIPEKLYAALLHWLPAATDGRAREAAAQGVEGGELG"
     gene            10284..13799
                     /gene="dnaE"
                     /locus_tag="P5537_11115"
     CDS             10284..13799
                     /gene="dnaE"
                     /locus_tag="P5537_11115"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HRV78633.1"
                     /translation="MTADPNTPDLAPHQPRFVHLRLHSEYSITDGIVQLDQAIAAAAD
                     DGMPALGVSDLANLFGMVKFYKGARGRGIKPIVGVDAWIRNEAERDKPHRVLLICRNR
                     TGYGQLCELLTRAYLENKHRGRAEMRREWFEGGAASALLCLSGAMSGDIGAAIAAGNL
                     ALAEQLAADWARLFPGAFYIELQRAGHPGTEGYIRHAVDIAGRLGLPVVATHPVQFLK
                     REDFKAHEARVCIAQGYVLADKRRPRDFTEEQYLKSQAEMCALFADLPEALENAVEIA
                     RRCSLTVQLGKNFLPLFPTPEGMTLDDFLVEEAKKGLEERLVQLYPHPEERERQRPRY
                     EQRLKFETDTIIQMGFPGYFLIVADFIQWGKNNGVPVGPGRGSGAGSLVAYSLKITDI
                     DPLEYALLFERFLNPERVSMPDFDIDFCQDNRYRVIEYVRERYGKDAVSQIATFGTMA
                     SKAVVRDVGRVLDLPYGLCDRLSKLIPIEGAKPVSLNKAYEMEPQIGEMMADGNDGES
                     VRDLWSLAQPLEGLSRNVGMHAGGVLIAPGKLTDFCPLYIADGDDATPVSQFDKDDVE
                     AVGLVKFDFLGLRNLTIIELALEYVARLEGSRPDLMSLGFEDPAAYQILKDANTTAIF
                     QVESDGMKKLLKKLAPDRFEDIIAVLALYRPGPLGSGMVDDFILRKKGQQEIDYFHPD
                     LKACLEPTYGVIVYQEQVMQISQIIGGYTLGGADMLRRAMGKKKADEMAKHRATIAEG
                     AKQKGYDPALAEQLFDLMTKFAEYGFNKSHTAAYAVVTYHTAWLKAHHCAAFMAATMS
                     SDLDNTDTVKIFYEDTLANGIKVLPPDVNTSDYRFVPVDRKTIRYGLGAVKGVGEPAV
                     RAILAARQKGGDFRDLFDFCERVDRRMVNRRVIEALIRAGAMDTLAGHKGLDRAQLMA
                     TVALAMEAAEQAAANAMQGGLFDLMPEAAGAAPEFARVRAWSERERLKEEKLAIGFFL
                     SGHPFNAFKPEVRRFVRRTLAQLEPSRDLTTLAGVVMEQRTKMGNRGKMVFVQIDDGT
                     EPREVTVYSEVLDASRGKIVTDEVVVIEAKVSNDDFSGGLRIIADRVLTLGEARGRFA
                     RALQLRINGEVGSTGGPVAAAGKLQTLLEPFREGGCPIRVRYRNAAAEAELPFGDGWR
                     VRLDDALLESLREWLPGEAVEVVYP"
     gene            complement(14011..14358)
                     /locus_tag="P5537_11120"
     CDS             complement(14011..14358)
                     /locus_tag="P5537_11120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004312334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HRV78634.1"
                     /translation="MPGRASQLPCGNSAVPDATAPAPDIIARRLRIHGLVQGVWYRGS
                     ATAEATRLGLAGWVRNRGDGTVEALAIGATAAVETFVAWAHRGPSNARVSRVEVFEAA
                     LEQLTGFEQRPTL"
     gene            complement(14372..16063)
                     /locus_tag="P5537_11125"
     CDS             complement(14372..16063)
                     /locus_tag="P5537_11125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004312333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015116 - sulfate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0008272 - sulfate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HRV78635.1"
                     /translation="MKLDFRPKLFDTLPGYSRAGLVGDLSAGITVGVLALPLAMAFAI
                     ASGMSPTAGIWTAIVAGFLIAFFGGSRVQIGGPTGAFIPIVYAIVVDHGVQNLLIATM
                     MSGVLLFAMGALRLGNMIRFIPLSVVIGFTNGIAVVIFISQIKDFLGLQIADLPGEFF
                     AKMAALAAALPSLHLPTVAVAVASLVILVAWNRQAARTAWMRRLPGPLAVLIIMTAVN
                     TLVALPVDTIGSRFGGIPQEIPAFGLPELSLSTLGKLIAPAITIALLGAIESLLSARV
                     ADSQIDDRHDPNQELMAQGIANVAAPLFGGFAATGAIARTATNIRTGGRTPIAGMIHA
                     GVLLAIVLALAPAASHIPLATLSAIVVIVSINMGEWHAFAPKELARYSLNYRTILLGT
                     FFITVVFDLTLAVEIGMALASLFFIYRMSDLTRIDRVPLEDFYGVEALSHPDGTPRIV
                     AYKLKGSLFFGAANKLENLLLGLPGHPEVVVLDLDKVINIDTTGLDILQTLHRNLQKR
                     GAHLVLCGLNSQPGSIVFRSGFSDKLGDNNITANLTEALIRAQRLGGREPEIAYA"
     gene            complement(16236..>16791)
                     /gene="metG"
                     /locus_tag="P5537_11130"
     CDS             complement(16236..>16791)
                     /gene="metG"
                     /locus_tag="P5537_11130"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004312332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="methionine--tRNA ligase subunit beta"
                     /protein_id="HRV78636.1"
                     /translation="HLMTRAERKQIDALLEANRESLAPTAAAPAKADKPAQDARDTKT
                     ASSQQRHAEKQQHSAQAAETATEHISIDDFTKVELRIARIADAQHVEGADKLIRLSLD
                     IGETDAAGNPKPRQVFAGIKSAYDPATLVGRMTVMVANLAPRKMKFGLSEGMVLAASD
                     TAGNTPGIFLLSPDAGALPGMKVK"
BASE COUNT         2593 a         5729 c         5937 g         2532 t
ORIGIN      
        1 cgcgtcccgg atcgcctgta ggagctgcgg cagctgcgaa cccggcggtt cggtaaatgc
       61 cgcgcgtgca gcactgcgcc gccgccttcg cgccggccgg cgctcctaca tgaaccacga
      121 cgcgtcccgg agcgccttat gtcgcggggc tcaggtgccg tacttgcggg ccagggtgtc
      181 gtgaagcgcg acgaactcct gcgacagctt gtgcttcggg tcgaggtgga tcatcggctt
      241 ggcctgctcg tgcgattcct tgatcttgat cgaggccgac aggtagggct gcagcaccgg
      301 caggccctcg tcgatgagct cctgcaccac cttctgcggc aggctggcgc gcggctggaa
      361 ctggttgacc acgatgcctt cgacctcgag gccgcggttg tggtcggact tgatctcctg
      421 cacgttctcg agcagcgagt acagcgcctt gcgggagaac tcgtcgcaat cgaaggggat
      481 caggcaggca tcggcggcga tcagcgccga gcgggtgaag aagttcaacg cgggcggggt
      541 gtcgatgaag acgcagtcga agtcctgcgc cagctcctca agagcgtcgc gcagcttgta
      601 gatcttgtag cgcgactcca gcttcgactg cagctcctcg agctgcggat gcgagggcat
      661 cacgtgcagg cgctcgaagg gggtggcgac gacgaactcc gcggtgtcgc gcgggttgag
      721 cttgaagttg agcgtctggt cgaagaagtc cgcgagcgtc gcatccaggc cgtccacgcc
      781 ggcaccgagc aggtactggg tggagttgcc ctgcgggtcg aggtccacca ccagggtgcg
      841 cttgccctga gcggcggcga tcgccgcgag gttgcaggtg atcgtcgact tgcccacgcc
      901 gcccttctga ttgaatacca cccgtcgcat cgccttctcc cctgtcgtca tgtgcgcgcg
      961 gctgctcgcc ggccccgcat tctgccaaaa accggcgccg ccggcgcgcc aggcagacgc
     1021 aaggcgcgat tccacgtgat cctgcgcatc agcggcgggc gtgtccaagg tcggggcgct
     1081 ggagtacact tccggggcgt cggtagccgg cgatcccgag ccggacggcg ccaacataaa
     1141 acaagcaggt ctgcggtcga gttccgaaca gcgtccagcc tcccgagcgg caagcccggg
     1201 acggcctgtg ctgcgtcgcg atcccggcgc ggcctcgacg aactcacaac ggctacctca
     1261 cagacacgag aggggagaac atggatcagg atttcatcac agcagcgctc gactaccacc
     1321 gctcgccgac gcgcggcaag atctcggtgg tgcccaccaa gggcctcacc aaccagcgcg
     1381 acctcgcgct cgcctattcg cccggcgtgg ccgcggcctg cgacgccatc gtcgccgacc
     1441 ccgccgaggc cttcgagctc accagccgcg gcaacctcgt cgccgtggtc accaacggca
     1501 ccgcggtgct cggcctgggc aacatcggcc cgctggcctc caagccggtc atggaaggca
     1561 agggctgcct cttcaagaaa ttcgccaata tcgacgtctt cgacatcgaa ctggcggaga
     1621 acgaccccga caagctgatc gagatcatcg ccgcgctcga gcccacgctg ggcggcatca
     1681 acctcgagga catcaaggcg cccgagtgct tctacatcga gaagaagctg cgcgagcgca
     1741 tgaagatccc ggtcttccac gacgaccagc acggcaccgc gatcatctcg gccgccggcc
     1801 tggtcaacgg cctcaaggtg gtcggcaaga acatcgccga cgtcaggctg gtgtgctccg
     1861 gcgccggcgc ggcggcgatc gcctgcctcg acatgatggt cagcgtgggc ctgcgccgcg
     1921 agaacatcta cgtgtgcgac tccaagggcg tcatctacga gggccgcgag cccaacatgg
     1981 agccgaccaa ggcgcgctat gcgcagaaga ccgaaggtcg cacgctgggt gacgtgatcg
     2041 ccggcgccga cgtcttcctc gggctgtcca ccgccggcgt gctcaagccc gagatggtgg
     2101 cgaagatggc cgacaagccg ctgatcttcg cgctcgccaa cccgaacccc gagatcctgc
     2161 cggccgatgc caaggccgtg cgccccgact gcatcgtcgc caccggccgt tcggactacc
     2221 cgaaccaggt caataacgtg ctgtgcttcc ccttcatctt ccgcggtgcg ctcgacgtcg
     2281 gcgcgaccac gatcaacgag gagatgaagc tcgcctgcgt gaaggcgatc gccgagctgg
     2341 ccgaggccga ggccagcgac atcgtcgcca gcgcctatgg cggccaggag ctcagcttcg
     2401 gctccgagta catcatcccg aagcccttcg acccgcgcct gatcgtcaag atcgcgcccg
     2461 cggtggcgaa ggcagcgatg gattcgggtg tggcgaccaa gccgatcgcc gacctcgagg
     2521 cctatgcctc cagtctcaac gctttcgtct atcagtccgg catcgtgatg aagccggtgt
     2581 tctcggccgc caaggcggtg ccgctggagc agaagcgcgt gatctacgcc gagggcgagg
     2641 acgagcgcgt gctgcatgcg gtgcgcgtgg tgctcgacga ggggctggca gcgccgatcc
     2701 tgatcggtcg ccccgaggtc atcgagatgc gcatcaagaa gatcggcctc aacctcaagc
     2761 cggggcgcga cttcgagatc gtcaaccccg agtccgaccc gcgctaccgc gagctgtggt
     2821 ccgactacta cgcgctgatg aagcgcgacg gggtcacccc ggacctggca aaggccaaga
     2881 tccgccgcga caccaccctg atcggggtca tgatgctgcg ccgcggcgac gccgacgcgc
     2941 tggtctgcgg caccttcggt tcctacgact accacctcaa gcaggtggcc gacgtgatcg
     3001 gcctcgcccc gggggccaag cagttcgcgg cgatgaacct gctgctgctc accaagcgca
     3061 tgctggccat caccgacacc tacgtgaatg aaagcccgag cgcggaggag gtcgccgaga
     3121 tcgcgcgcat ggcggccgac gagctgcgcc gcttcggcat cgagcccaac gtggcgctgc
     3181 tgtcgcactc cagcttcggc agctcgagct cggcctcggc gcgcaagatg cgtcgtgcct
     3241 gcgagatcct gcgcgagact tcgcccgatc tcaacgtcga tggcgagatg cacggcgacg
     3301 ccgccctgtc cgaggagatc cgcgacaagc tgcacccgga ttcgggcctg aagggcgagg
     3361 ccaacctgct cgtgatgccc aacctggacg cggccaacat ctccttcaac ctgatgaagg
     3421 tggccaacgg cgacggcgtg tcggtggggc cgatcctgct cggcgcggcc aagccggtgc
     3481 atatcgtgac gccctcggcc accgtgcgac ggctggtcaa catgaccgcg ctcgcggtgg
     3541 tcgacgccaa ggagtcgcgc aacgccgggg cctgaggccc gctggcggtg ccggtcggca
     3601 ccgccccggc gcgagcctcc cgcgacgggg ttcgcgcagc gtgttcctgg ggcagctccg
     3661 cgaggggctg ccccgctttg tttccttctt ccccgacagg cgatcccgat gccgaagacc
     3721 acctccccgc gcgcgctgct gttcgccggc gcgcttgccc tgagcgcccc ggccgcgcag
     3781 gctgccgact ggctgctcgc ctcctccagt ccgcgggtcg tgcccggcca gcgcttcgag
     3841 gtcgtggtga tcggcgaggg ccgcgcggcg gaatggccgg cgcgcctgcc ggcgagcatc
     3901 gagctgcctg ggggcgggcc ctccatcgcg gtcgagctgg tcgcgatcgg caaggcggcg
     3961 gcgggggccg gccagcgccg ctacttcgcg cgctggccga tggaggtggc cggagtggcg
     4021 gcgctcgcgc tcgtcggcag gccctcggcg cgggtgctgc tcgatgccgg cgcgccggcc
     4081 ggcgtggccg cagcccctgc cgtgccggcc gccgtcgtgc ccgcggtgcc ggtcgccgct
     4141 gcggctgcac cggccgcggt ggcaccgatg gcccccgtcg ccgcggctcc ggccgacgcg
     4201 gtgccggtcg agccctcggg cttcggcttc cacgaaccga tgtactttct catcggcggt
     4261 cgcgacccgg tgtctgcgcg ctttcagttc agcttccgct accgcatctt cgacgagcag
     4321 ggcgtggtgg cggagtcgat cccggtggcg agcgggctct acttcggttt cacccagacc
     4381 tcgctgtggg acctgcagtc cgagtccaag cccttccgcg actcgagctt ccgcccctcg
     4441 ctgttctacc gcttcgccct cgacgatccc gacaagcgcg gctcgctggc gctctccggc
     4501 ggctacgagc acgaatccaa cggccaggag gacatgccct cgcgcagcat cgacacgctc
     4561 ttcgtgcgcg ccgacgcgcg tctgcgcctg gacgaagcgg gcacctacct cggcgtcgtg
     4621 cccaaggcgt ggacctacct cgaccgcgag gacaacccag acatcgcgcg ctaccgcggc
     4681 cacgccgaac tcggcctgcg cctcggccgc gacgacggct ggctgttctc cacgctgatc
     4741 cgtcgcggca ccgagggcaa gatgggcacg cagtacgacc tgtcctatcc gatccggcgc
     4801 agcgtgttct ccggcgtggg cgccttcgtg catctgcagg ccttcaaggg ctacggcgag
     4861 accctgctcg aatacgacga gaacaaggaa gcgcagtacc gcatcggcgt ctcgctggta
     4921 cgctagagcg cgcccaacgg ccgtgcccga ccaaccccaa ggagaatccg atgaaccatg
     4981 cgatccgaat ccaccgcacc ggcggtcccg aagtcctgca gtgggaggcc gtcgagctgc
     5041 cgccgcccgc ggccggcgag gtgcggctgc gccaccatgc ggtggggctc aatttcatcg
     5101 acacctatca ccgtagcggc ctgtacccgc tgcccttgcc ctcggggctg ggcatggagg
     5161 gcgcgggcgt ggtcgaggcg gtgggcgagg gcgtggccgg gctgaaggtg ggggaccgcg
     5221 tggcctacac cggtggcccg ctggacgcct actcggaggc gcgcaacatc gaggcgcgcc
     5281 acctcgtggc cttgccggac gacctctcct tcgagcaggg cgcggcgatg atgctgcagg
     5341 gcatcaccgc gcaatacctc ttacatgcca cctacccggt gaaggcgggc gagaccatcc
     5401 tggtgcatgc ggcggccggc ggcgtcggct cgatcctcgt gcagtgggcc aagctgctcg
     5461 gcgccaccgt gatcggcacc gtgggcaacg acgacaaggc gcagcgcgcg cgtgccctcg
     5521 gctgcgacca cgtcatcgtg tactcgcgcg agaagttccc cgagcgcgtg cgcgagctca
     5581 ccggcggcgc gggcgtcgcg gtggtgtacg actcggtggg gcgcgacacc ttcctcgact
     5641 cggtggcctg cctgcgccgg cgcggcacca tggtgagcta cggcaacgcc accggcgcgg
     5701 tcgccccctt tgactgcgcg ctgctgcaca aggccggctc ggtctatgtc acccgtcccg
     5761 gcctgcccga ctacatcgcc agccgcgcgg agttggtcga gcgcgccgcg gcgctgttcg
     5821 aggtggtgcg cagcggccgg gtgaagatcg agatcctgca gcgctacgcg ctcaaggacg
     5881 ccgcccaggc gcaccgcgat ctcgaggcgc gcaagaccac cggctccacc atactgcttc
     5941 cctgagtgcg cttgcgcgcc cgcgccgggc gccgctgcgg ccggcagggg gcgtcctagt
     6001 cgagcagcac atagcggccg tcgcggatct gggtgaagta gaccgtccgc ggcgtgtcgc
     6061 cattggcgtc gaaggcgatc tgctgctgca gcccctggaa cggggcgtgg cgcaccaggg
     6121 cctgcttgag cgtctcgtcc tccgtgcgcc tttgcatcgc gtcgaacagc acggtcgctg
     6181 cgtcgtaggc cagcaccgag ctgtatccgg gctcgcgctg gaagcgcttg aagtaggcgc
     6241 tgcggaaggc ctggtagcgt gccgagcggt cgtcgcggtc gaaggcctgc acgatcacca
     6301 gcgcctccag cgccttgccg ccgagctcga tcagcttctc gctcgccgcc cactccgccg
     6361 cggcgatcgg cagctgcggc gcctgcagct tggcgtgctg gcacagccgg gtaaggtcga
     6421 tcgccgcggc gaggaacatc agtccatcgg gttcggcagc gagcatcgcg cgcatgacct
     6481 cgccgaagtc ggcgtcgggc cgcgattcga aggtcaccgc ggcgacggtc ttgccgccca
     6541 ggccgctgaa ggcggcctca aactccctga accacgattc ggtgaaggag cggttgcgca
     6601 ggtcgtaggc cacggccacc cggcgctgcc cctgcgcgaa cagccgcctg gcgtagtcgt
     6661 gggcgttgtc gcgggtggtc cggttgatgc ggaagagata gtcgtcgttg ccgtagaagt
     6721 ccatcgaggt gatggtcggg ctcaccatca ccacccggtt gcggttgatg tgcggcagcg
     6781 cggccgccgc catcgcgctc gcgaagggac cgacgatggc ctcgaccttc gcctcgatca
     6841 gctccgccgc gcccttcgcg gcgatctccc gcgtctgcgc gtcgtcgcgc accagcaact
     6901 cgagcggccg gccgtggatg ccgccggcgg cgttgcgctc ctcgagcgcg agctggacgc
     6961 cgttgcgccc ggcctcgccg acgtcggagg cacgatggct cagccccccg aggaagccga
     7021 ttcggatggg ctcgcggggc tggcagccga gcagggcgag actggcgagg gcagtggcga
     7081 ggacagggcg gatcatcggc ggtttgcggg tggttttaga agattagagt ctataatcgc
     7141 gaagataaac tgaaacgtca aaaacatcac aaagtttgga tgtgcctggc gtttatcgtg
     7201 ccgattcact ctcaaagacc agacctgcgc gtcgccgcgc ccggtccggg gcgcccggcc
     7261 tgaaacgaaa gatggaccac ttcccgaccg ccttcgacgg cacccgagcg cgtcttccac
     7321 gagcgacggc aacgcgcgcg gccgtgtcgc cgtcgcagcc cggcacccgc aggagcgctg
     7381 aacgatgagg ccgagcacag gcgcgcaagg cggcgcgcgc tggtcgatcc gtgcccgtct
     7441 gctggcgatc gggctgaccc cgctgctgct ggggtttccg ttgatcatgg cgctcctggt
     7501 gttctggggc ggttcgtatt tcgaccgcat cgtcatcgcc aacgccagga cccacctcgc
     7561 cggcaacgag cgctatctag aggacgtgcg ccgccaggcc gaggagcgcg tgggccagct
     7621 tgccgagtcc aggccgatgc ggcgcctgct cgacgaggcg ggccccgccg aggaggtcgc
     7681 ggcgatcctc gccagccggg cggagactgc agggctggat ttcctcgtga tcgccacggc
     7741 cgagggtgag gtgctggtcg gcaccgccgg acggccgcac ggcggccggt tgccacgcag
     7801 cttcacgctc cgccaggcgc gccagggcct ggcggccgcg gccttcgaac gccttgaccc
     7861 gaaccagctc gccgcgatcg atccgggcct gccagcgcgg gtgcgcgtgc tcaccccggc
     7921 tgggcaggct cgccctggcc ttggcggcgt cgaggaacac ggcttgctgc tgacggtggc
     7981 cgcacccatc gcatcggccg ccggcgaggt ggatcgggtt ctcttcggag gactcgcgct
     8041 gagcggcaac gaggccctcg tcgatcgcat gcgcgatgtc gtcttcccgg ccggcaccct
     8101 gcccgacggc accgagggcc agaccagcct gctgctggac agccggcgcg tcgccaccac
     8161 cttgcgcctg gccggcggcg agcgcgcggt ggggagcttt gccgagcccg aggtgctcgc
     8221 ccacgtgctc gagcagggca acatctggct ggcgcgcgcc agcgttctcg gtgaatccat
     8281 gatcgccggc tacgcaccga tccatgatgg cgacggcgag cgcatcggca tgctcttctc
     8341 cggctttccc gaggcgccct accagcgcga gaagctgcag ctcttcgccg ccgtgggcgg
     8401 actcttcttg ctgctgacct tgctgctgtc cgggctctac gttgggtggt cgcgccggat
     8461 caccgcgccg ctgacgcgca tcatgggcac catgagcgcg gcggcggcgg gcgatctctc
     8521 cgcccgcgtc ggcgcgcccg aacgcgacga cgaggtcggc cgcctcgggc ggcagctcga
     8581 caccatgctc gacgcgctta cctcggagac cacccgccgc gaggcgctct tcgacaacat
     8641 gcgcgacgga ctggtgctga tcgacgcgaa cggtgcggtg cgcgattgca accggcagtt
     8701 cgccgccatg ctcggctaca cgcgcgagga ggcccgcggc ctgcacgtct gggagtggga
     8761 tcgcagcatc gagcgccccg cgctgatgga catgctgcag cgcaccgacg ccctgcagaa
     8821 cctgttcgag accctgcagg agcgcaagga cggcagccgc ttcatcgccg aggtctcatc
     8881 gagccgggtg gagtggggcg gcgactccta cgtgctggcg atgcagcgcg acatcggcgc
     8941 gcgcaagcag gtcgaagccg aactcgagcg tcatcgcgag cacctcgagg ccatggtgcg
     9001 cgaacgtact gcggcgcttg ccgaggcgcg cgaccaggcc gaggccgcca gccgcgccaa
     9061 gagcgccttc ctcgccaaca tgagccatga gatccgcacg ccgatgaacg cgatcatcgg
     9121 cctgtcggaa ctgctgctgc gcgagggcag cgacgggcgc agcagcgatc gcctcggcaa
     9181 gatccagggc gcggcccatc acctgctcgg catcatcgac gacatcctcg acctgtcgaa
     9241 gatcgaagcc ggaaagctcg ggatcgagcg cgccgagttc gtcctgtccg atctcgtggg
     9301 ccgtgcggtg gccctggtgc gcgagcgcgc cggtgacaag ggtctgcgcc tgcgcagcga
     9361 gatcgacccg gtgctgcccc gtgcgcttgc cggcgatccg gtccgcctca cccagatcct
     9421 ggtcaatttc ctctccaacg cggtgaagtt cgccgatacc ggcgacatcg tcgtgcgcgc
     9481 ccgccaggtt gccgcggagg gcgggatggt tcacctgcgc ctggaggtgg tcgatcaggg
     9541 catcgggatc gatcccgccg aacagctgcg catcttcaag gctttcgagc aggccgacgg
     9601 ctcggtgacg aagaagtacg gcggaaccgg gctcgggctc gcgatcagca agcgcctggc
     9661 gacgctcatg ggcggggaga tcggtgtcga gagcgcgcca gggcagggca gcaccttctg
     9721 gatccgcgtg ccgctggcgg tcgtgcagcc gtcggtccag ccgctcgcga gcgctgcggc
     9781 ggcgcccgcg gccgtcccgg cggcgtcgag cgctcaccag ctgctgcgcg agacgcgcgc
     9841 cgggcggcgc atcctgctcg tcgaggacca ccgcatcaac caggaggtgg ccaaggcctt
     9901 gctgcggcgc gccgggctgg tggtcgaggt ggccgagaac ggccggatcg ggctcgatcg
     9961 cgtgcgcgaa cacgactacg acctggtgct gatggacatc agcatgccgg tgatggacgg
    10021 gctggaggcg acgcgcgcga tccgcacgct gccgggccgc ggcgccgacg tgctacccgt
    10081 cctggcgatg accgccaacg ccttcgagga cgaccgcgag gcctgcctgg cggccgggat
    10141 gaacgaccac atcgccaagc cggtgatccc cgagaagctc tacgccgcgc tgctgcactg
    10201 gctgccggcg gcgacggacg gcagggcgcg cgaggctgca gcgcagggcg tggagggggg
    10261 cgagctcggg taaaatcggc gccatgactg ccgacccgaa cacccccgac ctggcgccgc
    10321 accagccgcg cttcgtccat ctccgccttc actccgaata ctcgatcacc gacggcatcg
    10381 tccagctcga ccaggcgatc gccgccgcgg cggacgacgg catgccggcg ctcggcgtct
    10441 ccgacctcgc caacctgttc ggcatggtca agttctacaa gggcgcgcgc ggcaggggca
    10501 tcaagcccat cgtcggcgtc gacgcctgga tccgcaacga ggccgagcgc gacaagcccc
    10561 accgcgtgct gctgatctgc aggaaccgca cgggctatgg ccagctgtgc gagctgctta
    10621 cccgcgccta cctcgagaac aagcaccgcg gccgcgccga gatgcgccgc gagtggttcg
    10681 agggcggcgc ggcgagcgcg ctgctgtgcc tgtcgggcgc gatgagcggc gacatcggcg
    10741 cggcgatcgc ggccggcaac ctcgcgcttg ccgagcagct cgccgccgac tgggcgcggc
    10801 tcttcccggg tgccttctac atcgagctcc agcgcgccgg ccaccccggg accgagggct
    10861 acatccgcca cgcggtggat atcgccggcc ggctcggcct gccggtggtg gcgacccatc
    10921 cggtgcagtt cctcaagcgc gaggacttca aggcgcacga ggcgcgggtg tgcatcgcgc
    10981 agggctacgt gctcgccgac aagcgccggc cgcgcgactt caccgaggag cagtacctca
    11041 agagccaggc ggagatgtgc gcgctcttcg ccgacctccc ggaggcgctc gagaacgcgg
    11101 tcgagatcgc ccgccgctgc tcgctgacgg tgcagctggg caagaacttc ctgccgctct
    11161 tccccacccc cgagggcatg acgctcgacg actttctggt cgaggaggcg aagaagggcc
    11221 tggaggagcg cctcgtccag ctctacccgc accccgagga gcgcgagcgg cagcgcccgc
    11281 gctacgagca gcgcctgaag ttcgagaccg acacgatcat ccagatgggc ttccccggct
    11341 acttcctgat cgtggccgac ttcatccagt gggggaagaa caacggcgtg ccggtcggcc
    11401 cggggcgcgg ctctggcgcg ggctcgctgg tggcgtattc gctcaagatc accgacatcg
    11461 acccgttgga gtacgcgctg ctgttcgagc gcttcctcaa ccccgagcgg gtgtcgatgc
    11521 ccgacttcga catcgacttc tgccaggaca accgctaccg cgtcatcgag tacgtgcgcg
    11581 agcgctacgg caaggacgcg gtgagccaga tcgccacctt cggcaccatg gcctcgaagg
    11641 cggtggtgcg cgacgtcggc cgcgtgctcg acctgcccta cggcctgtgc gaccggctgt
    11701 cgaagctgat cccgatcgag ggcgccaagc ccgtctcgct gaacaaggcc tacgagatgg
    11761 agccgcagat cggcgagatg atggccgacg gcaacgacgg cgagtcggtg cgcgacctgt
    11821 ggagcctggc gcagccgctc gagggcttga gccgcaacgt cggcatgcac gccggcggtg
    11881 tgctgatcgc gcccggcaag ctcaccgact tctgcccgct ctacatcgcc gacggcgacg
    11941 acgccacgcc ggtgtcgcag ttcgacaagg acgacgtcga ggccgtgggc ctggtgaagt
    12001 tcgacttcct cggcctgcgc aacctcacca tcatcgagct cgcgctggag tacgtggcgc
    12061 gtctggaggg cagccggccc gacctgatga gtctgggctt cgaggacccc gccgcctacc
    12121 agatcctgaa ggacgccaac accacggcga tcttccaggt cgaatcggac ggcatgaaga
    12181 agctgctgaa gaagctcgcg cccgaccgct tcgaggacat catcgcggtg ctcgcgctct
    12241 accgtcccgg tccgctcggc tcgggaatgg tggacgactt catcctgcgc aagaagggcc
    12301 agcaggagat cgactacttc caccccgacc tcaaggcctg cctggagccg acctacggcg
    12361 tcatcgtgta ccaggaacag gtgatgcaga tctcccagat catcgggggc tacacgctgg
    12421 gcggcgccga catgctgcgc cgcgcgatgg gcaagaagaa ggccgacgag atggccaagc
    12481 accgcgccac catcgccgag ggcgcgaagc agaagggcta cgacccggcg ctcgccgagc
    12541 agctcttcga cctgatgacc aagttcgcgg agtacggctt caacaagtcg cacaccgcgg
    12601 cctacgcggt ggtcacctac cacaccgcct ggctcaaggc gcaccactgc gcggccttca
    12661 tggcggcgac gatgtcgtcc gacctggaca acaccgacac ggtcaagatc ttctacgagg
    12721 acacgctcgc caacggcatc aaggtgctgc cgccggatgt gaacacctcc gactaccgct
    12781 tcgtgccggt ggatcgcaag accatccgct acggcctggg cgcggtgaag ggcgtgggcg
    12841 agccggcggt gcgggcgatc ctcgccgcgc ggcagaaggg cggagacttc cgcgacctgt
    12901 tcgacttctg cgagcgggtg gaccggcgca tggtgaaccg ccgcgtcatc gaggcgctga
    12961 tccgcgccgg cgcgatggat acgctggcgg gccacaaggg cctggaccgc gcgcagctga
    13021 tggcgaccgt ggccttggcg atggaggcgg ccgagcaggc ggcggccaac gcgatgcagg
    13081 gcgggctctt cgacctgatg cccgaggccg cgggcgcggc gccggagttc gccagggtga
    13141 gggcgtggag cgagcgcgag cgcctcaagg aagagaagct cgcgatcggc ttcttcctct
    13201 ccggccaccc cttcaacgcc ttcaagcccg aggtgcgccg cttcgtgcgc cgcacgctgg
    13261 cccagctcga gccctcgcgc gacctcacca cgctggccgg ggtggtcatg gagcagcgca
    13321 ccaagatggg caaccgcggc aagatggtct tcgtgcagat cgacgacggc accgagcccc
    13381 gcgaggtcac ggtgtactcc gaagtgctcg acgccagccg cggcaagatc gtcaccgacg
    13441 aggtcgtggt gatcgaggcc aaggtgagca acgacgactt ctcgggcggg ctacgcatca
    13501 tcgccgaccg cgtgctgacg ctgggtgagg cacgtggtcg ctttgcgcgt gccctgcaat
    13561 tgcgcatcaa tggagaggtc ggcagcacgg gcgggccggt agccgcagcg ggcaagctgc
    13621 agaccttgct cgagcctttc cgcgaagggg gctgcccgat tcgggtgagg tatcgcaacg
    13681 ccgccgccga ggccgagctc ccgttcggtg atggctggcg tgtgcgcctg gacgatgccc
    13741 tgctggagag cctgcgcgaa tggctgccgg gcgaggcggt cgaggtggtg tacccctgag
    13801 gcgcgatcgt ttaggcaggg gcgccgccag gcgcaaaggc ggcccttgcg catccgaccg
    13861 agcttacgac cgcggcgtcg gtgcgcggcg gctggcgttc ctgcaggcgc atggagccgc
    13921 gatgcttccc gtaggagcgc cggcaggcgc gatagcggcc gttcggtctc cgccctgcgt
    13981 cggccgcccg cggtagcggc ggggctgtgc tcaaagcgtc gggcgttgtt cgaagcctgt
    14041 gagctgctcg agcgcggcct cgaacacttc cacgcgcgac acgcgcgcgt tcgacgggcc
    14101 gcggtgggcc caggcgacga aggtctcgac cgcggccgtc gcgccgatcg cgagcgcctc
    14161 gaccgtcccg tcgccgcggt tgcgcaccca gccggcgagg ccgaggcggg tggcctcggc
    14221 ggtggcgctg ccgcgatacc agacgccctg cacgagaccg tggatgcgca ggcggcgggc
    14281 gatgatgtcg ggtgccggtg cggttgcatc cggaaccgcc gagtttccgc acggcaactg
    14341 cgaggctcgg ccgggcatgg acgatttccc gtcaggcata ggcgatctcc ggttcgcgcc
    14401 cgcccaggcg ctgggcgcgg atcagcgcct cggtgaggtt ggcggtgatg ttgttgtcgc
    14461 cgagcttgtc gctgaagccc gagcggaaca cgatcgagcc gggctgcgag ttgagcccgc
    14521 acagcaccag gtgggcgccg cgcttctgca ggttgcggtg cagggtctgc aggatgtcca
    14581 gcccggtggt gtcgatgttg atcaccttgt ccaggtccag caccaccacc tcggggtggc
    14641 ccggtagccc gagcagcagg ttctcgagct tgttggcggc gccgaagaag aggctgccct
    14701 tgagcttgta ggcgacgatg cgcggcgtgc cgtcggggtg ggacaaggcc tcgacgccgt
    14761 agaagtcctc cagcgggacg cggtcgatgc gggtgaggtc ggacatccgg tagatgaaga
    14821 acaggctcgc cagcgccatg ccgatctcga ccgccagggt gaggtcgaac accacggtga
    14881 tgaagaaggt gccgagcagg atggtgcggt agttcagcga atagcgcgcg agttccttgg
    14941 gcgcgaaggc gtgccattcg cccatgttga tcgacacgat gaccacgatc gccgacagcg
    15001 tggcgagcgg gatgtggctg gccgcggggg cgagcgcgag cacgatcgcc agcagcacgc
    15061 cggcgtggat catgcccgcg atcggggtgc ggccgccggt gcggatgttg gtggcggtgc
    15121 gggcgatcgc gccggtggcg gcgaagccgc cgaagagcgg cgcggcgacg ttggcgatgc
    15181 cttgcgccat cagctcctgg ttggggtcgt ggcggtcgtc gatctggctg tcggccaccc
    15241 gcgccgacag cagcgactcg atcgcgccga gcagcgcgat cgtgatcgcc ggcgcgatca
    15301 gcttgccgag cgtggacagg ctcagctcgg gcaggccgaa ggcggggatc tcctgcggga
    15361 tgccgccgaa gcggctgccg atggtgtcga ccggaagcgc gaccagggtg ttcaccgcgg
    15421 tcatgatgat cagcaccgcg agcgggccgg gcaggcggcg catccacgcg gtcctggccg
    15481 cctggcggtt ccacgccacc aggatcacga gcgaggccac cgccaccgcc accgtgggca
    15541 ggtgcaggct cggcagcgct gccgcgagcg cggccatctt ggcgaagaac tcgcccggca
    15601 gatcggcgat ctgcaggccg aggaagtcct tgatctgcga gatgaagatc accaccgcga
    15661 tgccgttggt gaagccgatc acgaccgaca gcgggatgaa gcggatcatg ttgcccaggc
    15721 gcagcgcacc catggcgaac agcagcacgc ccgacatcat cgtggcgatg agcaggttct
    15781 gcacgccgtg gtcgaccacg atcgcatata cgatggggat gaaggcgccg gtggggccgc
    15841 cgatctgcac ccgcgagccg ccgaagaagg cgatcaggaa gccggcgacg atcgccgtcc
    15901 agatgccggc ggtgggcgac atgccggagg cgatcgcgaa ggccatcgcc agcggcagcg
    15961 cgagtacgcc gacggtgatg cctgcagaca gatcgccgac gaggcctgcc cggctgtagc
    16021 cgggcagggt gtcgaagagc ttgggacgga agtcgagttt catgctgtct ccgctgcgta
    16081 ctggttcagg acggggcgcg aggcccgggc ggcgccgccc gcgtcgatgg caggcaggcg
    16141 gcgcggagcg cggagacgat caccctcggc cggcgtgatg caggacgatc cagcgtttcg
    16201 agggggtgag cggcatgacg gctactcggg gcgggtcact tcaccttcat gccggggagc
    16261 gcgccggcgt cgggcgagag caggaagatg cccggcgtgt tgccggcggt gtcggaggcg
    16321 gcgagcacca tgccctcgct caggccgaac ttcatcttgc gcggcgcgag gttggcgacc
    16381 atcaccgtca tgcggccgac cagggtggcc gggtcgtagg ccgacttgat gccggcgaag
    16441 acctggcgcg gcttcgggtt gccggccgcg tcggtctcgc cgatgtcgag cgacaggcgg
    16501 atgagcttgt cggcgccttc gacgtgctgg gcgtcggcga tcctggcgat gcgcagctcg
    16561 accttggtga aatcgtcgat cgagatgtgc tcggtggcgg tctccgcggc ctgcgccgaa
    16621 tgctgctgct tctcggcgtg gcgctgctgg gacgaggcgg tctttgtgtc cctggcgtcc
    16681 tgcgcgggtt tgtccgcctt cgccggcgcg gccgcggtcg gggcgagcga ctcgcggttg
    16741 gcctcgagca gggcgtcgat ctgcttgcgc tcggcgcggg tcatcaggtg g
//
LOCUS       DAOTIN010000071        15910 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_4436_length_15910_cov_9.572185, whole genome shotgun sequence.
ACCESSION   DAOTIN010000071 DAOTIN010000000
VERSION     DAOTIN010000071.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 15910)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 15910)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15910
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4436_length_15910_cov_9.572185"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..462
                     /locus_tag="P5537_11135"
     CDS             <1..462
                     /locus_tag="P5537_11135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HRV78637.1"
                     /translation="LYLPSGSSSEERQQVKFDFMDRFLPHMDQLFQSGQEVVVCGDWN
                     IAHREADLKNWKSNQKNSGFLPEERAWLSRLFDEQGWIDVYRRLHPEATADCYTWWSN
                     RGQAWAKNVGWRLDYQVATPGLAASAQAAEVYKAQRFSDHAPLTVDYDWTL"
     gene            complement(542..1246)
                     /locus_tag="P5537_11140"
     CDS             complement(542..1246)
                     /locus_tag="P5537_11140"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78638.1"
                     /translation="MKILLSALVAGLSMAALPTLAAELAPIAPMVPTTSMVPTPPPTP
                     PLAQLPAAAAPAQPKIARGLLLLHEGRVFMAPCRDRSYVNVEDVSEAGAVLAALRDFG
                     LAPGNNLYVELMGVQEGGLLRVSGLNFAHAGARCLGEAENEEDWRALGLQAEWAAAAG
                     AGALRVERVDAPELRTSYDAVKDDQGARSIEAEGVALSFTPGLCRTADGKMLTGWRAT
                     LVPAGGGALEGCGWER"
     gene            complement(1316..2131)
                     /locus_tag="P5537_11145"
     CDS             complement(1316..2131)
                     /locus_tag="P5537_11145"
                     /inference="COORDINATES: protein motif:HMM:NF015722.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
                     /protein_id="HRV78639.1"
                     /translation="MEFLSSAGTCLRSAFFVAFALAASLAAAEEASVWREPATGMEFV
                     RVPGGCFDMGDTFGDGETNELPVHKVCMTPYWIGRHEVTQAQWTRLMDYNLSVFAGSP
                     AHPVDSINQADIAEFVRRLGEKNPGRVFRLPTEAEWEYACRGGGRAERFGGEAAPEGA
                     NTAERAEREGDGSLPVGSYAPNALGIHDMSGNLWEWVSDVYAADAYLHHQAENPHYQS
                     SGPARLLRGGGWTHPAGFARCSKRHMHCRPTARFDFVGFRLVLEEGADGRPAH"
     gene            complement(2241..3158)
                     /locus_tag="P5537_11150"
     CDS             complement(2241..3158)
                     /locus_tag="P5537_11150"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HRV78640.1"
                     /translation="MAPIAGKSLNLRSIEIDLDQFKIGLIAFGFALSSAPGGPRLRVG
                     NGRQRLRPPGKPMSIPRDGDKPLDNTFGRQSVSTDERRQRIRDVFDHIASRYDLMNDL
                     MSFGIHRLWKRRFVAGLPDQGLFVDLAGGTGDVAALLARKPGRRVVVVDPSIPMMREG
                     STRADAATVRWIAGEAERLPFADGSVQALTVSFGLRNTTRLDVALAEAARVLAPGGTF
                     ACLEFSRPMKWLQLFYDPYSFHVIPRLGAWVAANPAAYQYLIESIRNFPDQQRFAAMI
                     EAAGFSSVRWKNLSFGIAAIHLATRPLVR"
     gene            3473..5764
                     /gene="nosZ"
                     /locus_tag="P5537_11155"
     CDS             3473..5764
                     /gene="nosZ"
                     /locus_tag="P5537_11155"
                     /EC_number="1.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050304 - nitrous-oxide reductase activity
                     [Evidence IEA];
                     GO_process: GO:0019333 - denitrification pathway [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-dependent nitrous-oxide reductase"
                     /protein_id="HRV78641.1"
                     /translation="MKKFAVKTTALLIAAGLGVGAAGSAFAAESLQDVMKRRNLTQQD
                     LLAAAKTYTPSGGRDEFLAFASGGQSGQMIVYGVPSMRILKYIGVFTPEPWQGYGFDE
                     ESKKVLAGGNIDGKSITWGDTHHPAISETNGEYDGQFLFINDKSNPRLAVIDLRDFET
                     KQIVANPIMKSEHGGAFATPNTEYIIEASQYASPLENQKFYPLEQFNEKYRGAVTYWK
                     FDREHGQLKADQSFSLELPPYSQDLSDAGKLDSDGWSFTNSFCTERYVGGIEKGRPPY
                     EAGCSAKDTDYMHVVNWKRAAEIAKDDKNVKIINNHRVIPMEVAIREGILFLIPEPKS
                     PHGVDVTPNGKFIVVSGKLDTHVSVYSFEKIMDAIKNKRFESKDPYGIPVIGMKDALH
                     TQVQLGLGPLHTQFDAKECVAYTSLYVDSMVAKWNFCEGKLLDKIAIHYNIGHLMTME
                     GDTTKPKGKYLVALNKLSIDRFNPVGPLHPQNHQLIDISNDKMQLLYDMPLPLGEPHY
                     VVGIQADKLKPAVRYKVGTNSRTDQQHEGKVRAGEEKTVREGNQVKVYGTLIRSHITP
                     ETIEVEQGDEVTIYLTNLERAQDETHGFTVSTYNVHASVEPGKTISVKFKADKEGVYP
                     YYCTEFCSALHLEMQGYLLVKPKGWKPEEGAQLAAANYTETDYKNTLKKVADTQAVID
                     QVVAYITSVNYKAYPEVVALMEDATDQLGKMPEAKAKHEAAAAKQDWEQANLWAEQVW
                     QYQVKAADIGLRAKTFLEQKGAK"
     gene            5862..6170
                     /locus_tag="P5537_11160"
     CDS             5862..6170
                     /locus_tag="P5537_11160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c"
                     /protein_id="HRV78642.1"
                     /translation="MKLIVSLLLAATVSAPAFAALDGAKLYAEKTCNACHGADAKKPL
                     LPTYPKLAGQNAAYAEQQMKDIKSGARNNGQTAAMKGVMHLVNDEEIKAIAIWLESLK
                     "
     gene            6264..6977
                     /locus_tag="P5537_11165"
     CDS             6264..6977
                     /locus_tag="P5537_11165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="c-type cytochrome"
                     /protein_id="HRV78643.1"
                     /translation="MKITVLLAALLSASVAFAGPPAPKKTGIEGEGYVWNAQEGEKIE
                     ALQKKGDITRGEEAYEVCGACHLPSGAGRPDGTFPQLAGQHTTVLIKQMADIRAGLRD
                     NPTMYPFAATLVDPQELADVSAYIESLCIPTDHGKYEGADAAMQVAKGKDLYEKQCKE
                     CHGDTGAGDKAKFYPVIAGQHYKYLLRQMTEIRDGHRRNANPDMVKVIKPYTDDQLVA
                     ISAYQASLKMPGSMCSDKK"
     gene            7084..8079
                     /locus_tag="P5537_11170"
     CDS             7084..8079
                     /locus_tag="P5537_11170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78644.1"
                     /translation="MSATQNKNGLIAGLTFVALVALVAAYFAPLWWVSLTAPNYPEDA
                     FPDGIRIHFHFDGVKNGCSTPPKTSRLAEETMAEDMGEGTGRYNPILAEQTTLSGAAT
                     ALDCVHEMNTINHYVGMYPIATGGPVETKLSKFFVAFFAVMLLTFAVRDRKLRLGIMG
                     VGFGGLAAWMIVDQFVMGNLAAHVKHYMDESATFFNDPERIAAWGKNVEVISKVAIFG
                     MIAAMGVVIFGVLKLRNFELLLALIPGLLPIFYLIEYSGWLWFFGHNLHPWGAFTVKP
                     FMPTVFGEGKVAQFSTYSYPHWGYGLLMVVFVCLMLALLLRRKQLREEQAQGSAR"
     gene            8092..9474
                     /gene="nosD"
                     /locus_tag="P5537_11175"
     CDS             8092..9474
                     /gene="nosD"
                     /locus_tag="P5537_11175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071941 - nitrogen cycle metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrous oxide reductase family maturation
                     protein NosD"
                     /protein_id="HRV78645.1"
                     /translation="MSLLHRLTLLAAAVALALPAAQARDSDDEDQARGPGSGADFSTA
                     PRVDVHKPVQLIPLYLRDKRIHGLQPFQELVDKAPEGSVLKVPAGHYSGPVHLKKRLT
                     IEGEGEVVIDGGDKGTVFVLETNEATLRNLTITGSGESHDSDDTCLNIRGHGNLVENL
                     NIADCLFGIDLKQADHNIVRNNKVRSKDFELGVRGDGIRLWYSHDNLIENNLVTDTRD
                     MVAWYSHRNIYRGNEGRRSRYSIHFMFANDNIVENNRFYDNAVGVYFMYMEGGAARGN
                     IISHATGATGMGLGFKESSDILLENNEVIYCAVGVGSDLSPFQPDTTIRFVNNRFAFN
                     GIAIQLTSELGGNEMYGNTFEGNLTDMYQAGRGEGVKNKWEGNYFDTYQGFDRDEDGA
                     GDTPHEEYAYADRIWMEIPNARFFKTSPVLELLDFLERLAPFSTPDLQARDEKPLYIK
                     PERRIEGSAS"
     gene            9471..10334
                     /locus_tag="P5537_11180"
     CDS             9471..10334
                     /locus_tag="P5537_11180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HRV78646.1"
                     /translation="MSEKENTPAAAPAKGEVPVSRERARQGRRKVLRTILLTGGVLGS
                     GLSGYLPLVYARTNRLRPPGALDEKDFLSSCIKCGQCVQVCPVNAIKLADLIDGFGVG
                     VPYIDARAQACDFSCDAVQCILACPTGSLTYHKPDFLPVREGAALSQKPTLIAKMNDP
                     EPTLNMTERMGVARLTRPESCLAMKGEGFKGQARGPDFKGTMRYIKVDRWKPIPVADH
                     PYDLPLCDLCMRECPIAGAISLEKFTGPDGKTRARPIVHENCVGCGVCEMICPTEPAS
                     ITIIPREVWKS"
     gene            10331..11308
                     /locus_tag="P5537_11185"
     CDS             10331..11308
                     /locus_tag="P5537_11185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NapH/MauN family ferredoxin-type protein"
                     /protein_id="HRV78647.1"
                     /translation="MSKLLTRRFIDQIKVMFGKEPAKPAEISPAAQKIHFYKKNNRDE
                     IAELKHRRAHEKPSHKWRNRRWATLIFANLLFVFSYWLDIQVLEGALTASRFVGFHMA
                     DLNSALQVMLAHKHIITNLLIGTATVLLLWALLGGRTFCSWVCPYHLVAEWAEKIHLY
                     LAKKKLVTDQPIDRRLRSVFWIVFALLAVVTGYTVFEAISPTGILSRALIYGAGLSLL
                     WVVALLVFEVFFSRRAWCRYACPIGLTYGVVGIISPVRIKYKLEGCFHEGDCRKVCLV
                     PHVLDTVIKGRAVEPEVPLGPDCTRCGLCVDACPTGSLSFEVKGLSKLL"
     gene            11364..12221
                     /locus_tag="P5537_11190"
     CDS             11364..12221
                     /locus_tag="P5537_11190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV78648.1"
                     /translation="MIRLQNVRKTFRSARVLDGISLEVGLGERIALIGSNGAGKTTLI
                     RCLLGEYVHDGEVSVDGVNPRRERATVLANVGFVPQLPPPLKMPVGQLIDFAAGLCGT
                     APARIDDIARRLGLEIDAIRSRQFVRLSGGMKQKLLIAIALGRDARLLIMDEPAANLD
                     PEARKIFFDLLAERVQNATMLISSHRLDEVSALVNRVIEMDTGRIVLDDQVADMGALH
                     SRLDCRIVLKQPDPAIAKALQGWKFAFDAEDTAWTGEIAGADRLRFLGVVSRYTGLVT
                     KLDMTERPH"
     gene            12224..12712
                     /locus_tag="P5537_11195"
     CDS             12224..12712
                     /locus_tag="P5537_11195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011287321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78649.1"
                     /translation="MCDHHRRQFIGRLAKGGLLLTPLAAALSGCTDDKWPEGMKSIIW
                     DRDTCVRCNMAISDRRFAAELRGGPKDTVFKFDDPGCLVFWLEEKRERFPWMAEAATR
                     MWVADYNSKSRDEMIWHDPRKVRYITRTSPMGYNYAAAADSATDSVSFEEMRQQTLAK
                     GK"
     gene            12718..13545
                     /locus_tag="P5537_11200"
     CDS             12718..13545
                     /locus_tag="P5537_11200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011287320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HRV78650.1"
                     /translation="MKQFWLTARLDIVESLRARWFQVYTLVFGGIVALLFLFGLTESR
                     VLGFIGLSRLLVTYIQLTMAILPIFVLITTVRSVAGDREAGVFEYLLSLPVSLWAWFW
                     GKFVGRYIVIFMPVFAAMLLAVGWATVQDIEVPWEMFAYYTALIAAMAMCFLGFGMLI
                     SSIARSTDVAQGAAFLAWLLFLLFLDLILLGVMIQERISPELAVTIALANPLQVFRTA
                     ALSMFDPQLIVLGPSAYVILDLFGVAGYKVFAVAYPAALGVVSAALGFLVFRRGDLP"
     gene            13562..14521
                     /locus_tag="P5537_11205"
     CDS             13562..14521
                     /locus_tag="P5537_11205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018991860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prenyltransferase"
                     /protein_id="HRV78651.1"
                     /translation="MSVDKSLAEPVRDPFPNAFARYLAATRPAFLTVTFAGSLIGLGT
                     AFADGLSIDWARALVTILFALVAHAGANVVNDYFDALNGTDALNTELLHPYTGGSRFI
                     QNGYLSLAEMRRFGYLLLAAVIPGGLWLTLGAGPGLLAIGLAGLLVAWAYSAPPFKLM
                     SRGMGELAITAGWLLVVLGTDYVQRGELAALPLVAGLPFALLVAAILYINQFPDRRAD
                     EAAGKRTVVVRLGPRAASRGYMALVAFAHLWLAGALAAGAVPAGAALALLPLVFSVRA
                     ARALLADAEHPARLVAPIRDTIAAANLSGLLLAIGLGAAGLLA"
     gene            14518..14850
                     /locus_tag="P5537_11210"
     CDS             14518..14850
                     /locus_tag="P5537_11210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78652.1"
                     /translation="MSRPSDRVLAFTLFAAALFAATFVDAGIRRDAHEPALQRTERLV
                     EDLRLSDLVLFTEARYTRHLSQADLHSAFQDHPVALEHFPSGSLLPPPALLLDRHEPL
                     DREAAPSD"
     gene            14813..>15910
                     /locus_tag="P5537_11215"
     CDS             14813..>15910
                     /locus_tag="P5537_11215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HRV78653.1"
                     /translation="MNRWIEKQRHLIDFTASSLARRKGKSLGLLVVYTLLVFVLASVS
                     LYTHALRNEATRVLAGTPEVVLQRLIAGRHDLIPPGYIEKIGRVRGVQKIEGRLWGYY
                     YDSVLKANYTFMVPSDRRIAEGEIVVGPALERSRGLAEGNGISFRAYSGELHTFIVSE
                     VLAHESELVNADLVLMSEADFRRFFAYPDGHYTDIALWVANPQEVRNVGLKLINALPD
                     SRPILREEVLRTYASIFDWREGMMLALLSAAILAFGIFAWEKAAGLSAEEKREIGILK
                     AIGWETGDVIAMKFWEGFLVSLLAFLLGYVAAYVHVFHFEFALFAPVLQGWAVLYPSF
                     ALTPKIDGLQVATLFVFSVLPYTAATLVPIWR"
BASE COUNT         2791 a         5656 c         4955 g         2508 t
ORIGIN      
        1 ctctacctgc cctcgggctc gagctcggag gagcgccagc aggtgaagtt cgacttcatg
       61 gaccgcttcc tgccgcacat ggaccagctc ttccagagcg ggcaggaggt cgtggtgtgc
      121 ggcgactgga acatcgccca ccgtgaggcc gacctgaaga actggaagtc gaaccagaag
      181 aactccggct tcctgcccga ggagcgcgcg tggttgagcc gcctgttcga cgagcagggc
      241 tggatcgacg tctatcgccg cctgcacccc gaggccaccg cggactgcta cacgtggtgg
      301 tcgaaccgcg gccaggcgtg ggcgaagaac gtcggctggc gcctggacta ccaggtggcc
      361 accccagggc tggccgcgag cgcgcaagcg gcggaggtct acaaggcgca gcgcttctcc
      421 gaccacgcgc cgctgacggt ggattacgac tggacgctgt aggggccgcg cacgcggcga
      481 tgcgggaggg cacccgaccc cgggcggcgg cgcagcggcc ggccgcccct gacgcgccgc
      541 gtcagcgctc ccagccgcag ccttcgagcg cgccgccccc tgccggcacc agcgtcgcgc
      601 gccagccggt aagcatcttg ccgtcggccg tccggcacag gccgggcgtg aagctcagcg
      661 ccacgccctc ggcctcgatg ctgcgcgcgc cctggtcgtc cttcaccgcg tcgtagctcg
      721 tgcgcagctc gggcgcgtcg acgcgctcga cccgcagcgc gcccgcaccg gcggccgccg
      781 cccactcggc ctgcaggccg agcgcgcgcc agtcttcctc gttctcggct tcaccgaggc
      841 agcgtgcgcc ggcatgggcg aagttgagcc ccgacacgcg cagcaggccg ccctcctgca
      901 cgcccatcag ctcgacgtag aggttgtttc caggcgccag gccgaagtcg cgcagcgcgg
      961 cgagcaccgc acccgcctcg gaaacgtctt ccacgttgac atagctgcga tcgcggcagg
     1021 gcgccatgaa cacccgcccc tcgtgcagca gcaacaggcc gcgggcgatc ttgggctgcg
     1081 cgggcgcggc ggcggcggga agctgcgcca gcggcggcgt cggcggcggc gtcggcacca
     1141 tcgaggtcgt cggcaccatc ggcgcgatcg gcgcgagctc cgcggccagc gtgggcaggg
     1201 cggccatcga caggccggca acgagtgcgg aaagcagaat cttcatcggt tcccctgaaa
     1261 tccttgcggt gccaccgggc aagcggcccg gcgacttgaa aaagccggag cgtacttaat
     1321 gcgcgggccg tccgtctgcg ccctcctcca gcaccagccg gaagccgacg aagtcgaagc
     1381 gcgccgtggg ccggcaatgc atgtggcgct tgctgcagcg cgcgaagccc gcgggatgcg
     1441 tccagccgcc gccgcgcagc aggcgcgccg gaccgctgga ctggtagtgc ggattctcgg
     1501 cctgatggtg caggtaggcg tcggccgcat agacgtccga cacccactcc cacaggttgc
     1561 cgctcatgtc gtggatgccg agcgcgttgg gcgcatagct tcccaccggg agactgccat
     1621 cgccctcgcg ctcggcgcgt tctgcggtgt tggccccttc gggcgcagcc tcgccgccga
     1681 agcgctccgc gcgcccgccg ccgcggcagg cgtattccca ctctgcctcg gtggggaggc
     1741 ggaacacccg gccggggttc ttctcgccga gccgacgaac gaactcggcg atgtcggcct
     1801 ggttgatgct gtcgaccgga tgcgccggcg agccggcgaa caccgacagg ttgtagtcca
     1861 tcaggcgggt ccattgcgcc tgggtgacct cgtggcggcc gatccagtaa ggcgtcatgc
     1921 acaccttgtg taccggcagc tcgttggtct cgccgtcgcc gaaggtgtcg cccatgtcga
     1981 agcagccccc cggcacgcgc acgaactcca ttccggtcgc gggctcgcgc cacaccgagg
     2041 cctcctcggc ggcagccagt gaagccgcca aggcgaacgc gacgaaaaac gcggagcgca
     2101 aacaggtgcc ggccgatgaa aggaattcca tttcgttttc ctggataaag tccgaacaat
     2161 tcaaatgaga actcggcttt accattgcgc gttcattcat tgaaaattct gccgacaccc
     2221 gaaagacccg gatcgggttg tcaacgcaca agcggtctcg tcgcaagatg aatcgccgca
     2281 attccgaagc tcaggttctt ccagcgcacc gaagaaaaac cggccgcctc gatcattgcg
     2341 gcaaagcgct gctgatccgg gaaattgcga atcgactcga tcaggtactg gtacgccgcc
     2401 ggattggccg cgacccacgc accgaggcgc gggatcacgt ggaaggaata gggatcgtag
     2461 aacagctgca gccacttcat cggccgcgag aactccaggc aggcgaaggt gccgccgggc
     2521 gccagcacgc gcgcagcctc ggcgagcgcg acatcgagcc gcgtggtgtt gcgcaggccg
     2581 aaggagacgg tgagcgcctg aaccgacccg tcggcgaagg gcaggcgctc ggcctcgccc
     2641 gcgatccagc gcaccgtggc cgcgtcggcg cgggtgctgc cctcgcgcat catcgggatc
     2701 gacgggtcga ccacgaccac ccgccggccc ggcttgcgcg ccaggagggc cgcaacgtcg
     2761 ccagttccgc cggcaagatc gacgaacagc ccctggtccg gcaggccggc cacgaagcga
     2821 cgcttccaca ggcggtggat gccaaagctc atcaggtcgt tcatcaggtc gtagcgcgag
     2881 gcgatgtggt cgaacacgtc gcggatgcgc tgccggcgct cgtcggtcga gaccgactgg
     2941 cggccgaagg tgttgtcgag cggtttgtca ccgtcgcgag gaatgctcat gggttttcca
     3001 ggaggtcgga gccgctgccg tccgtttccg acccgaagac ggggtccgcc gggcgcagac
     3061 gaaagtgcga atccgaaagc aatcaaacca attttgaatt gatccagatc aatttcaatt
     3121 gaccggagat tcagcgactt gccagcaatg ggcgccaagt ttagatgccg caactgcatt
     3181 tttccatcgc attccggtac agagcgtgca cttgatccat gtcaagcttg cccgtcgata
     3241 aggagtcgat aattcgggca cgccagcgac ggaggtcgac gctgcggcaa tgggaaaagt
     3301 ttcacgcccg tgacccgcag gagcattcgg gccatgttcg gtgaacgtgg cacgcagccc
     3361 ccggattccg cacaggtgcg gatgcacgac ctccaggcat acggggggac ggccgagctg
     3421 ggccgcaagg tgaaggcagt tcgaaactgt tgtttctacg ggagtttcca aaatgaaaaa
     3481 attcgcagta aaaaccacgg ccctgctcat cgcggcgggt ctcggcgtgg gtgcggccgg
     3541 ctcggcgttc gccgcggagt cgctgcagga cgtcatgaag cgccgcaacc tcacccagca
     3601 ggacctgctg gccgcggcca agacctacac cccgagcggc ggccgtgacg agttcctcgc
     3661 cttcgcctcg ggcggccagt ccggccagat gatcgtctac ggtgtcccgt cgatgcgcat
     3721 cctgaagtac atcggcgtgt tcactcccga accctggcag ggctacggct tcgacgaaga
     3781 atccaagaag gtgctcgccg gcggcaacat cgacggcaag tcgatcacct ggggcgacac
     3841 ccaccacccg gcgatctccg agaccaacgg cgagtacgac ggccagttcc tgttcatcaa
     3901 cgacaagtcc aacccgcgcc tggccgtgat cgacctgcgc gacttcgaga ccaagcagat
     3961 cgtcgccaac ccgatcatga agtcggagca cggcggcgca ttcgcgaccc cgaacaccga
     4021 gtacatcatc gaggcctcgc agtacgcctc gccgctcgag aaccagaagt tctatccgct
     4081 cgagcagttc aacgagaaat atcgcggcgc cgtcacctac tggaagttcg accgcgagca
     4141 cggccagctg aaggccgacc agtccttctc gctcgagctg ccgccctact cgcaggacct
     4201 ctccgacgcc ggcaagctgg actccgacgg ctggtccttc accaacagct tctgcacgga
     4261 acgctacgtc ggcggcatcg agaagggccg cccgccgtat gaggccggtt gctccgcaaa
     4321 ggacaccgac tacatgcacg tggtgaactg gaagcgtgcc gcagagatcg cgaaggacga
     4381 caagaacgtc aagatcatca acaaccatcg cgttatcccg atggaagtgg cgatccgcga
     4441 aggcatcctg ttcctcatcc ccgagcccaa gagcccgcac ggcgtcgacg tgaccccgaa
     4501 cggcaagttc atcgtggtgt ccggcaagct cgacacccac gtgtccgtgt attccttcga
     4561 gaagatcatg gacgcgatca agaacaagcg cttcgagtcc aaggacccat acggcatccc
     4621 cgtcatcggc atgaaggacg cgctgcacac ccaggtccag ctcggcctcg gcccgctgca
     4681 cacccagttc gacgccaagg agtgcgtggc ctacacctcg ctgtacgtcg actcgatggt
     4741 cgcgaagtgg aacttctgcg aaggcaagct gctggacaag atcgccatcc actacaacat
     4801 cggccacctg atgacgatgg aaggcgacac caccaagccc aagggcaagt acctggtggc
     4861 gctcaacaag ctgtcgatcg accgcttcaa cccggtgggc ccgctgcacc cgcagaacca
     4921 ccagctgatc gacatcagca acgacaagat gcagctcctg tacgacatgc cgctgccgct
     4981 gggcgagccg cactacgtcg tcggcatcca ggccgacaag ctcaagccgg ccgtgcgcta
     5041 caaggtcggc accaacagcc gcaccgacca gcagcacgaa ggcaaggtgc gcgcgggcga
     5101 ggagaagacc gtccgcgaag gcaaccaggt caaggtgtat ggcacgctga tccgctcgca
     5161 catcaccccg gagaccatcg aggtcgagca gggcgacgag gtcacgatct acctgaccaa
     5221 cctcgagcgc gcacaggacg agacccacgg cttcaccgtc tcgacctaca acgtgcacgc
     5281 ctcggtcgag ccgggcaaga ccatctcggt caagttcaag gccgacaagg aaggcgtgta
     5341 tccgtactac tgcaccgagt tctgctcggc gctgcacctc gagatgcaag gctacctgct
     5401 ggtcaagccg aagggctgga agcccgagga gggcgcgcag ctcgccgccg ccaactacac
     5461 cgagaccgac tacaagaata ccttgaagaa ggttgcggac acccaggcgg tcatcgacca
     5521 ggtcgtcgcc tacatcacct cggtgaacta caaggcctat ccggaagtcg tcgcgctgat
     5581 ggaagacgcc accgaccagc tcggcaagat gccggaagcc aaggccaagc acgaggccgc
     5641 cgccgccaag caggactggg agcaggcgaa cctgtgggcc gagcaggtgt ggcagtacca
     5701 ggtcaaggcg gccgacatcg gcctgcgtgc caagaccttc ctggagcaga agggcgccaa
     5761 gtaagaccgg cccctcgaag ttgaatcgat aatccagtag tccgcgtcgg ggagcgaagc
     5821 cagaggcgag ctccccgaca ctttagaagg aacaggaatc catgaagctg atcgtctccc
     5881 tgctgctggc ggccacggtg tccgcccccg ctttcgccgc cctcgacggc gccaagctct
     5941 acgccgagaa gacctgcaac gcctgtcacg gcgccgacgc caagaagccg ctgctgccca
     6001 cctatcccaa gctcgccggc cagaacgcgg cctatgccga gcagcagatg aaggacatca
     6061 agagcggcgc gcgcaacaac ggccagaccg cggcgatgaa gggcgtgatg cacctcgtca
     6121 acgacgaaga gatcaaggcg atcgccatct ggctcgagag cctgaagtaa gcctccacgc
     6181 tgccgcgcac cccggtgccc ggcagatcga gcccattgac ggaccgcccc ccctccgtcc
     6241 caatccccta gaggaccaaa atcatgaaga tcaccgttct gcttgccgcc ctcctctccg
     6301 ccagcgtcgc cttcgccggc cctcccgccc cgaagaagac gggcatcgaa ggtgaaggct
     6361 atgtctggaa cgcccaggaa ggcgaaaaga tcgaagccct gcagaagaag ggcgacatca
     6421 cccgcggcga ggaagcctac gaggtctgtg gcgcctgcca cctgccctcc ggcgccggcc
     6481 gccccgacgg caccttcccg caactcgccg gccagcacac caccgtgctg atcaagcaga
     6541 tggccgacat ccgcgccggc ctgcgcgaca acccgacgat gtacccgttc gctgcgaccc
     6601 tggtcgaccc gcaggagttg gccgacgtct ccgcctacat cgagagcctg tgcatcccga
     6661 ccgaccatgg caagtacgag ggcgccgacg ccgcaatgca ggtcgccaag ggcaaggatc
     6721 tctacgagaa gcagtgcaag gaatgccacg gtgacaccgg cgccggcgac aaggccaagt
     6781 tctacccggt catcgccggc cagcactaca agtacctgct gcgccagatg accgagatcc
     6841 gcgacggcca ccgccgcaat gccaaccccg acatggtcaa ggtcatcaag ccctacaccg
     6901 acgaccagct ggtggcgatc tccgcctacc aggcgagcct gaagatgccg ggctccatgt
     6961 gcagcgacaa gaagtgatcg gctgacccct ccgctgcgcc gtccgtctcg caccggggtg
     7021 cgcgcacact ctcgcgcgca ccccggggcc tcccaacccc tccccttgcg accggagctc
     7081 gaaatgtccg caacccaaaa caagaacggc ctgatcgccg gcctcacgtt cgtggcgctg
     7141 gtggcattgg tcgccgccta cttcgcaccc ctgtggtggg tatcgctgac ggccccgaac
     7201 taccccgagg acgccttccc tgacggcatc cgcatccact tccacttcga cggcgtcaag
     7261 aacggctgct ccacgccccc caagacctcg cgtctcgccg aagagaccat ggccgaggac
     7321 atgggtgaag gcaccggccg ctacaacccg atcctcgccg agcagaccac actcagtggc
     7381 gcggccacgg cactcgattg cgttcacgag atgaacacga tcaaccacta cgtcggcatg
     7441 tacccgatcg ccaccggcgg tccggtcgag accaagctct ccaagttctt cgtcgccttc
     7501 ttcgcggtca tgctgctcac cttcgccgtg cgcgaccgca agctgcgcct gggcatcatg
     7561 ggcgtcggct tcggcggtct ggccgcatgg atgatcgtgg accagttcgt catgggcaac
     7621 ctcgccgcgc acgtcaagca ctacatggac gagtccgcga ccttcttcaa cgaccccgaa
     7681 cgcatcgccg cctggggcaa gaacgtcgag gtcatctcca aggtcgccat cttcggcatg
     7741 atcgccgcca tgggcgtggt gatcttcggg gtgctcaagc tgcgcaactt cgagctgctg
     7801 ctcgcgctga ttcccggact gctgccgatc ttctacctga tcgagtactc cggctggctg
     7861 tggttcttcg gccacaacct gcacccctgg ggcgccttca cggtcaagcc cttcatgccc
     7921 acggtgttcg gcgagggcaa ggtggcgcag ttctccacct actcctatcc gcactggggc
     7981 tacggcctgc tgatggtcgt cttcgtctgc ctgatgctcg ccctgctgct gcgccgtaag
     8041 cagctgcgcg aggagcaggc ccagggcagc gcacggtaag gatgccccct cgtgagcctc
     8101 cttcaccgct tgacattgct cgccgcggca gtggccttgg ccctgcccgc ggcccaggcc
     8161 cgggacagcg acgatgagga ccaggcccgt gggcccggct ccggcgccga cttctccacc
     8221 gcaccgcggg tcgacgtcca taagccggtc cagctgatcc cgctctacct gcgcgacaag
     8281 cgcatccacg gcctgcagcc cttccaggag ctggtcgaca aggccccgga aggcagcgtg
     8341 cttaaggtcc cggccggcca ctactccggg ccggtgcatc tgaagaagcg cctgaccatc
     8401 gagggcgagg gcgaggtcgt catcgacggc ggcgacaagg gcacggtctt cgtcctggag
     8461 accaacgagg ccacgctgcg caacctgacc atcaccggct cgggcgagtc tcacgactcc
     8521 gacgacacct gcctgaacat ccgcgggcac ggcaacctgg tcgagaacct gaacatcgcc
     8581 gactgcctgt tcggcatcga cctcaagcag gccgaccaca acatcgtgcg caacaacaag
     8641 gtgcggtcga aggacttcga gctcggcgtg cgcggcgacg gcatccgcct gtggtacagc
     8701 cacgacaacc tgatcgagaa caacctcgtc accgacaccc gcgacatggt ggcgtggtac
     8761 tcgcaccgca acatctaccg cggcaacgag ggccggcgca gccgctactc gatccacttc
     8821 atgttcgcca acgacaacat cgtcgagaac aaccgcttct acgacaacgc cgtcggcgtc
     8881 tacttcatgt acatggaggg cggcgcggcg cgcggcaaca tcatctcgca cgccaccggc
     8941 gccacgggca tggggctggg cttcaaggag tcctcggaca tcctgctcga gaacaacgag
     9001 gtcatctact gcgcggtggg agtcggctcc gacctctcgc ccttccagcc cgacaccacc
     9061 atccgcttcg tcaataaccg cttcgcgttc aacggcatcg ccatccagct caccagcgaa
     9121 ctcggcggca acgagatgta cggcaacacc ttcgagggca acctgaccga catgtaccag
     9181 gccggacggg gcgaaggcgt caagaacaag tgggaaggga actacttcga cacctaccag
     9241 gggttcgacc gcgacgagga cggcgccggc gacaccccgc acgaagaata tgcctacgcc
     9301 gaccggatct ggatggagat ccccaacgca cgcttcttca agacctcgcc cgtcctcgaa
     9361 ctgctcgatt tcctcgagcg cctcgcgccg ttctcgaccc ccgacctgca ggcaagggac
     9421 gaaaagcccc tctacatcaa gccggagcgg cgcatcgaag ggagtgcatc atgagcgaga
     9481 aggaaaacac ccccgcagcc gcgcccgcca agggcgaggt gccggtctcg cgcgaacgcg
     9541 cgcgccaggg ccggcgcaag gttctgcgta ccatcctgct gaccggcggc gtgctcggct
     9601 ccggcctgtc cggctacctg ccgctggtct atgcgcgtac caaccgcctg cgcccgcccg
     9661 gcgcactcga cgagaaggac ttcctctcgt cctgcatcaa gtgcggccag tgcgtgcagg
     9721 tgtgcccggt caacgcgatc aagctcgccg acctgatcga cggcttcggc gtgggcgtgc
     9781 cctacatcga cgcccgcgcg caggcctgcg acttctcctg cgatgcggta cagtgcatcc
     9841 tcgcctgccc gaccggctcg ctgacctatc acaagcccga cttcctgccg gtacgcgagg
     9901 gcgcggcact gtcgcagaag cccaccctca tcgccaagat gaacgacccc gagcccacgc
     9961 tcaacatgac cgagcgcatg ggcgtggcgc gcctcacccg tcccgagtcc tgcctcgcga
    10021 tgaagggcga gggcttcaag ggccaggccc gcggccccga cttcaagggc acgatgcgct
    10081 acatcaaggt ggatcgctgg aagcccatcc cggtggccga ccacccctac gacctgccgc
    10141 tgtgcgacct gtgcatgcgc gaatgcccga tcgccggcgc catctcgctg gagaaattca
    10201 ccggccccga cggcaagacg cgtgcacgtc cgatcgtgca cgagaactgc gtcggctgtg
    10261 gcgtgtgcga gatgatctgc ccgaccgaac ccgcctcgat caccatcatc ccgcgtgagg
    10321 tgtggaaatc atgagcaagc tgctgacccg ccgcttcatc gaccagatca aggtgatgtt
    10381 cggcaaggaa cccgcgaagc cggccgagat ttccccggcc gcacagaaga tccacttcta
    10441 caagaagaac aaccgcgacg agatcgccga gctcaagcac cgccgcgcgc acgagaagcc
    10501 gagccacaag tggcgcaacc gccgctgggc gacgctgatc ttcgccaacc tgctgttcgt
    10561 gttctcctac tggctcgaca tccaggtgct cgagggcgcg ctcaccgcgt cgcgcttcgt
    10621 cggcttccac atggccgacc tcaactcggc cctgcaggtg atgctcgcgc acaagcacat
    10681 catcaccaac ctgctgatcg gcaccgccac cgtgctgctg ctgtgggccc tgctcggcgg
    10741 gcgaaccttc tgctcctggg tgtgtccgta tcacttggtt gcggaatggg cggagaagat
    10801 ccacctgtac ctggccaaga agaagctggt caccgaccag ccgatcgacc gccgcctgcg
    10861 ttccgtgttc tggatcgtgt tcgcgctgct cgccgtggtg accggctaca ccgtgttcga
    10921 ggccatctca ccgacgggta tcctgtcgcg cgcgctgatc tacggtgcgg gactgtcgct
    10981 gctgtgggtc gtggccctgc tcgtgttcga ggtcttcttc tcgcgccggg cttggtgccg
    11041 ctacgcctgc ccgatcggcc tgacctatgg ggtggtcggc atcatctcgc cggtgcgcat
    11101 caagtacaag ctggagggct gtttccacga gggcgactgt cgcaaggtct gcctggtgcc
    11161 gcacgtgctc gacaccgtca tcaagggccg cgcggtcgag cccgaggtgc cgctcggccc
    11221 ggactgcaca cgctgcggcc tgtgcgtgga cgcgtgcccg accggctcgc tgagcttcga
    11281 agtcaagggg ctgtccaagc tgctgtgagg cagcccgggc ccccaacccc ggtgattccg
    11341 caacacataa caagagtcga tagatgatcc gactacagaa tgtccgcaag accttccgca
    11401 gcgcgcgggt gctggacggc atttccctcg aggtgggcct cggcgagcgc atcgcgctga
    11461 tcggctccaa cggcgccggc aagacgacgc tgatccgctg cctgctcggt gaatacgtcc
    11521 acgacggcga ggtcagcgtc gacggcgtca atccacgccg cgagcgcgcc acggtgctgg
    11581 ccaacgtcgg cttcgtgccg cagctgccgc cgccgctgaa gatgccggtc ggccagctca
    11641 tcgacttcgc cgccggcctg tgcggcaccg cgccggcgcg catcgacgac atcgcgcgcc
    11701 ggctcggcct cgagatcgac gccatccgct cgcgccagtt cgtccgcctc tcgggcggca
    11761 tgaagcagaa gctgctgatc gcgatcgccc tcggccgcga cgccaggctg ctgatcatgg
    11821 acgagcccgc cgccaacctc gaccccgagg cgcgcaagat cttcttcgac ctcctcgccg
    11881 agcgtgtgca gaacgccacc atgctgatct ccagccaccg cctcgacgag gtctcggcgc
    11941 tggtcaaccg cgtgatcgag atggacaccg gccgcatcgt gctcgacgac caggtcgccg
    12001 acatgggcgc gctgcacagc cggctcgact gccgcatcgt gctcaagcag cccgaccccg
    12061 cgatcgccaa ggccctgcag ggctggaagt tcgccttcga tgccgaggac accgcctgga
    12121 ccggcgagat cgcaggcgcc gaccgcctgc gcttcctcgg cgtggtctcc cgctacaccg
    12181 gcttggtcac caagctggac atgaccgaaa ggccccactg accatgtgcg accaccatcg
    12241 acgccagttc atcggacgcc tggcgaaagg ggggcttttg ctcacgccgc tcgccgccgc
    12301 gctgtcgggt tgcaccgacg acaagtggcc cgagggcatg aaatccatca tctgggaccg
    12361 cgacacctgc gtgcgctgca acatggcgat ctcggaccgc cgcttcgccg ccgagctgcg
    12421 tggcggtccc aaggacaccg tgttcaagtt cgacgatccg ggctgcctcg tcttctggct
    12481 ggaggaaaag cgcgagcgct tcccgtggat ggccgaggcc gccactcgga tgtgggtcgc
    12541 ggactacaac agcaagagcc gcgacgagat gatctggcac gacccgcgca aggtgcgcta
    12601 catcacccgc acctcgccga tgggctacaa ctacgccgcc gcggcagact ccgccacgga
    12661 cagcgtgagc ttcgaggaaa tgcggcagca gacgctggcg aagggaaaat aaggcaaatg
    12721 aaacagttct ggctcaccgc acgtctggac atcgtcgagt cgctccgcgc ccgctggttc
    12781 caggtctaca ccctggtgtt cggcggcatc gtcgccctgc tcttcctctt cggcctgacc
    12841 gaatcgcgcg tgctcggctt catcggcctg tcgcgcctgc tggtcaccta catccagctc
    12901 accatggcca tcctgccgat cttcgtgctc atcaccacgg tgcgctcggt ggcgggcgac
    12961 cgcgaggccg gcgtattcga atacctgctg tcgctgccgg tctcgctgtg ggcctggttc
    13021 tggggcaagt tcgtcggccg ctacatcgtg atcttcatgc cggtgttcgc cgcgatgctg
    13081 ctcgcggtgg gctgggcgac ggtgcaggac atcgaggtgc cgtgggagat gttcgcctac
    13141 tacaccgcgc tgatcgcggc gatggcgatg tgcttcctcg gtttcggcat gctgatctcg
    13201 tcgatcgcac gcagcaccga cgtcgcccag ggcgcggcct tcctggcgtg gctgctcttc
    13261 ctgctcttcc tcgacctgat cctgctcggg gtgatgatcc aggagcgcat ctcgcccgag
    13321 ctcgcggtca cgatcgcgct tgccaacccg ctgcaggtct tccgcaccgc cgcgctgtcg
    13381 atgttcgacc cgcagctgat cgtgctgggc ccctcggcct acgtgatcct cgacctcttc
    13441 ggcgtcgccg gctacaaggt cttcgcggtg gcctaccccg cggcgctcgg cgtggtgagc
    13501 gcggcgctcg gcttcctcgt cttccgccgc ggcgacctgc cctgatcgac ggcccgcgcg
    13561 catgagcgtc gacaagtccc tcgccgaacc cgtgcgcgat ccgttcccga acgcgttcgc
    13621 gcgctatctc gcggcgacgc ggccggcctt cctgacggtg accttcgccg gctcgctgat
    13681 cggcctgggc acggccttcg ccgacgggct ctcgatcgac tgggcacgcg cgctggtcac
    13741 gatcctgttc gcgctcgtcg cccacgcggg cgccaacgtg gtcaacgact acttcgacgc
    13801 cctcaacggc accgacgcgc tcaacaccga gctgctccac ccctacaccg gcggcagccg
    13861 cttcatccag aacggctacc tgagcctggc cgagatgcgc cgcttcggct acctgctgct
    13921 cgccgcggtg atcccgggcg ggctgtggct caccctcggc gccggccccg gcctgctcgc
    13981 gatcgggctg gccggcctgc tcgtggcctg ggcctactcg gcgccgccct tcaagctgat
    14041 gtcgcgcggc atgggcgaac tcgccatcac cgcgggctgg ctgctggtgg tgctgggcac
    14101 cgactacgtg cagcgcggcg agctcgccgc cctgccgctg gtcgccgggc tgcccttcgc
    14161 gctgctggtg gcggcgatcc tgtacatcaa ccagttcccc gaccgccgcg cggacgaggc
    14221 ggcgggcaag cgcaccgtgg tcgtgcgcct tggtccacgc gcagccagcc gcggctacat
    14281 ggccctggtc gccttcgccc acctgtggct cgcaggcgcg ctcgccgccg gcgcggtacc
    14341 ggccggcgcg gcgctcgccc tgttgccgct ggtgttctcg gtgcgggccg cgcgcgcgct
    14401 gctcgccgac gccgagcatc ccgcccgcct ggtggcgccg atccgcgaca ccatcgccgc
    14461 cgccaacctc tccggcctcc tgctcgcaat cgggctgggc gccgcgggcc tgctggcatg
    14521 agccgtccct ccgaccgcgt gctcgccttc acgctcttcg ccgccgcgct cttcgccgcc
    14581 accttcgtgg acgcggggat ccggcgcgac gcgcacgagc cggcgctgca gcgcaccgag
    14641 cgcctcgtcg aagacctgcg cctgtccgac ctcgtgctgt tcaccgaggc gcgctacacc
    14701 cgccacctca gccaggccga cctgcactcc gccttccagg accacccggt ggcgctcgag
    14761 cacttcccct cgggctcgct gcttccgccc cccgccctcc tgctggaccg ccatgaaccg
    14821 ctggatcgag aagcagcgcc atctgattga cttcaccgcc agctcgctgg cgcggcgcaa
    14881 gggcaagagc ctcggcctgc tggtcgtcta caccctgctc gtgttcgtgc tcgcctcggt
    14941 gtcgctgtac acccacgcgc tgcgcaacga ggccacccgg gtgctcgccg gcactcccga
    15001 ggtcgtgctg cagcgcctca tcgccggccg ccacgacctc atcccgcccg gctacatcga
    15061 gaagatcggt cgcgtgcgcg gcgtgcagaa gatcgagggg cggctgtggg gctactacta
    15121 cgacagcgtg ctcaaggcca actacacctt catggtgccg agcgaccgcc ggatcgccga
    15181 gggcgagatc gtcgtcggcc ccgcactcga gcgctcgcgc ggactggccg agggcaacgg
    15241 catctccttc cgcgcctact cgggcgaact ccacaccttc atcgtcagcg aggtgctggc
    15301 gcacgagtcc gagctggtga atgccgacct ggtgctgatg agcgaggccg acttccgccg
    15361 cttcttcgcc tatccggacg gccactacac cgacatcgcg ctgtgggtgg ccaacccgca
    15421 ggaggtgcgc aacgtcggcc tcaagctgat caacgccctg cccgactcgc gccccatcct
    15481 gcgcgaggaa gtgctgcgca cctacgcgtc gatcttcgac tggcgcgagg gcatgatgct
    15541 ggccctgctg tcggccgcca tcctcgcctt cggcatcttc gcctgggaga aggccgcagg
    15601 cctctcggca gaagagaagc gcgagatcgg catcctcaag gcgatcggct gggagaccgg
    15661 ggacgtgatc gcgatgaagt tctgggaagg cttcctggtc tcgctgctcg ccttcctgct
    15721 cggctacgtc gccgcctacg tgcacgtgtt ccacttcgag ttcgcgctct tcgcgccggt
    15781 gctgcagggc tgggcggtgc tctacccgag cttcgcgctg acgccgaaga tcgacggcct
    15841 gcaggtcgcc acgctgttcg tgttctcggt gctgccctac accgccgcca ccctggtgcc
    15901 gatctggcgt
//
LOCUS       DAOTIN010000072        15832 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_4461_length_15832_cov_8.853965, whole genome shotgun sequence.
ACCESSION   DAOTIN010000072 DAOTIN010000000
VERSION     DAOTIN010000072.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 15832)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 15832)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15832
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4461_length_15832_cov_8.853965"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..430)
                     /locus_tag="P5537_11220"
     CDS             complement(<1..430)
                     /locus_tag="P5537_11220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004381117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HRV78654.1"
                     /translation="MSTPFRTLALIGKYQSPDVAESVLSIARFLRDRGLAVLIEQGTA
                     SSIGGAHDFPVASYEHIGASADLAVVIGGDGTMLHTARRLIEHGVPLVGVNLGRLGFL
                     TDIARSSATERLAEILDGAFTAEDRFMLDVEVLRGGARVFH"
     gene            550..1578
                     /gene="hrcA"
                     /locus_tag="P5537_11225"
     CDS             550..1578
                     /gene="hrcA"
                     /locus_tag="P5537_11225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004381119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HRV78655.1"
                     /translation="MNPLDARSQILLKTLIERHIADGQPVGSRALSRYSGLELSPATV
                     RNVMSDLEEMGFIASPHTSAGRIPTALGYRFFVDSLLTVQPLENARVRALEGQLLPDQ
                     PQRLISSASHLLSELTQFAGVVVAPRKDAVRIRQFEFISLAENRILLIIVTTGGDVQN
                     RLLLTRRAYTSAELHGAATYLNEHFAGLSFEEIRRRVGDELRQLRSDMSELMAATVDA
                     GSDAAEDSATSYVLSGETKLLDIEDLSSNMSRLRELFKLFEQRTGLLQLLDLSNRAEG
                     VQIFIGGESGLAPLDGCSVITAPYEVDGQVVGSLGVIGPTRMAYDRVIPIVDITARLL
                     SNALSSRH"
     gene            1629..2726
                     /gene="hemH"
                     /locus_tag="P5537_11230"
     CDS             1629..2726
                     /gene="hemH"
                     /locus_tag="P5537_11230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004325 - ferrochelatase activity
                     [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HRV78656.1"
                     /translation="MPRSRPEPIYRHDSTPRTGVLLVNLGTPAAPTAAALRPYLKQFL
                     SDPRVVEIPRLVWWPILNGIILNTRPKASAQKYASIWTDEGSPLLVHTVRQTKLLAGY
                     LAKDGHDGLDVDYAMRYGSPSIGDTLDAMRARGCTRILVVPMYPQYSASTTATVVDEV
                     GRSLAQWRNQPEMRFVRNFHDDPGYIDALVKSVREHWAANGEPERLLLSFHGVPRRSL
                     DLGDPYHCECHKTGRLVAEGLGVARERVLVTFQSRFGKAEWLKPYTQPTLEQLAAQGV
                     RRVDVMCPGFVADCLETLEEIALECKEAFVEKGGQTFHYIPCLNERDAWIRALAALVR
                     SHLGNWLEIAPPDEAARKAALERARTLGAAQ"
     gene            complement(2784..4148)
                     /locus_tag="P5537_11235"
     CDS             complement(2784..4148)
                     /locus_tag="P5537_11235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HRV78657.1"
                     /translation="MNRIPERIGKYRIIKEIGRGATAVVYLAESPDYPEPVALKHVRF
                     DDKARDEAKWNRRLIKLLKAERVVSGRLDHPNIIRIHDASIEPDQAYVVMEYFPGGSL
                     ERYCSFQNLLPIHRTIGIIFKCCMALDHAYRQGIVHRDIKPANILVDEQDNVKITDFG
                     LALNINKKLDTDSTFIMGVGSPAYMSPEQIKGYPLNQKTDLYSLGVLLFHMLTGRLPF
                     RANNPAQLVYKIINADPPSVSQLNPDVPEQMDAVIRKALEKDLYSRYRNGAEFAKDLA
                     AVRYQILDEGHVHHDAERFARLRKLAFFTEFEDVDLWEVMRICAWRKVGSDLGLMREG
                     DIDQRFGIVLEGKVELSIEGRRVLEVGPGEVFGEQAWLDQLEHRQLLSAVSLDELSYL
                     EVNPAALALASEEVLERFRRQLGTVAARRLAAVSRQMAAHAPAAVRAVRAAPVVHDLQ
                     IVDY"
     gene            4319..5638
                     /locus_tag="P5537_11240"
     CDS             4319..5638
                     /locus_tag="P5537_11240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family hydrolase"
                     /protein_id="HRV78658.1"
                     /translation="MSEAVDLLINARWIVPVDPHEAVLADHAVAVRGGRIVDLLGQDA
                     ARTRYAADKVVELPQHVLIPGLVNLHTHAAMSLLRGIADDLPLMRWLQEAIWPAESRH
                     VSAAFVRDGTLLAAAEMIRGGITTCSDMYFHPEAAAEAFAAAGMRAVVGAVALEFPTS
                     YASDPDDYLRKGLAARDRWQGHPLLGFSIAPHAPYTVSDESFRHVQTLADELELPIHV
                     HIHETAQEIADSLAAHGCRPLARLARLGVLGSNLIGVHAVHVDEPDIELLARHGCSVA
                     HCPTSNMKLASGIAPVPRLLAAGIPVGLGTDGAASNNRLDLLQEMRHAALLAKVGSLD
                     ATALPAHAALRMATLDGARALGMDDRIGSIEIGKCADLCALELSAPQCRPCFDPVSHL
                     VYVCGRENVSHVWIGGETRVDKGISLLHINDTELLRLVSMWQTRLGN"
     gene            5739..6437
                     /locus_tag="P5537_11245"
     CDS             5739..6437
                     /locus_tag="P5537_11245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HRV78659.1"
                     /translation="MIKQSKKQMLMLAAIASIGLSAPSAFAQVNDVVVAGKGEIPYVI
                     DARNVVARSGTGLCWRTGYWSPAAASTAMAGEFPVGCACDKDIVPADKCTVKAAAAVP
                     APKPTADKVKLSADALFDFDKAVLKAEGKAKLDQLAAQAKSLKLEVILAVGHTDRLGS
                     NAYNQRLSERRAAAVKTYLVSKGVDANRVYTEGKGETQPVTGNKCDKVGGRAAQISCL
                     QPDRRVEVEVIGSK"
     gene            6538..7242
                     /gene="ubiG"
                     /locus_tag="P5537_11250"
     CDS             6538..7242
                     /gene="ubiG"
                     /locus_tag="P5537_11250"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004372723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008689 - 3-demethylubiquinone-9
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-polyprenyl-6-hydroxyphenol
                     methylase/3-demethylubiquinol 3-O-methyltransferase UbiG"
                     /protein_id="HRV78660.1"
                     /translation="MNTVNADPAELQKFSDLAHRWWDPASEFRPLHEINPLRLGWIDG
                     KAALAGKKVLDIGCGGGILAEGMASLGAEVTGIDLSEKALSVARLHLFESGHKVDYRH
                     MSAEALADELPGHFDVVTCMEMLEHVPDPASIVAACARLVKPGGHVFLSTLNRNPKSY
                     LFAIIGAEYLLKLLPAGTHEYARFIKPSELSRHCRNARLDVQEIIGLSYNPLTKTYSL
                     GRDTDVNYLIHTVAAG"
     gene            7379..10084
                     /locus_tag="P5537_11255"
     CDS             7379..10084
                     /locus_tag="P5537_11255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004372725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetate--CoA ligase family
                     protein/GNAT family N-acetyltransferase"
                     /protein_id="HRV78661.1"
                     /translation="MSFRHLKSLFNPRSIAVIGASARERRMGNVLMRNLLSGQFAGPI
                     MPVNPRRPSVAGVLTYPSVAALPQTPDLAIVCTPAPLVPRIVEELGERGTRAVMVMAN
                     QLDTTLGADGRPLERSILEITRRHEMRLLGGSTLGILVPGLGLNATFSQIAARPGKLG
                     FVSQRDTVGTMVLDWALRKKVGFSHFVSLGDSLDIGFGEVLDFLAADSGTRAILLYIE
                     SIQDRRAFMSAARAAARNKPVIAIKAGRSPNNPLMGVSDPLFLEMPNLVSHDDVHDAA
                     LRRAGILRVDQLEEMFGAAETVLRARPLRGNRLVVLSNGGGAGLMVEDSLYLAGYSLP
                     SLKEQTIERLRRFMSPGWNGRNPLEIRVDSEPACYERLLKILQEERDGDAVLLIHTPN
                     ALSSSMDTAQQVIATARETGINLMTCWVGDESVEKERNLFINAGIATFDSPEHAASAF
                     LHMHRHRIASEVLMEVPTSEPEAFKPDVARARAVIQGALAESRASLTESESKDVLAAY
                     GVPVIQTHLAASPEEAAQIAGRIGLPVALTLMSRDIRRKWDVGGVALNLESTEAVEVA
                     ARGMIERAGRAEPPVSVSGFTVQRMVMRGHARQLLIGVSTDRLFGPVIVFGEGGRALE
                     IFRGLAVGLPPLNKPLADDLIARSKAAALLEARGHLPAADRDALALTLTKVSQIVVDH
                     PEIHEMDINPVFVDEHGVQALDAHMRLRPATAHEHRLAIQPYPKALEEPSQLRDGRPI
                     LLRPIRPEDEPAHYAFLSRLTREDFIYRFFNYIPEFPRREMARLTQIDYDREMAFIAT
                     ATGPDGKPETLGVSRAVADPDNHTAEFALVIRSDLKRQRLGSILMDKLVRYAREIGIQ
                     RLVGEVMGENEPMLGLLKHLGFKLKASEEPGVVRAIFELRPPSEA"
     gene            complement(10501..11172)
                     /locus_tag="P5537_11260"
     CDS             complement(10501..11172)
                     /locus_tag="P5537_11260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HRV78662.1"
                     /translation="MNAKERILGKLRASLAGTTAVADDYDIGLVTDPWRYAADERIAR
                     LRRMLEAVHGETLLTTAAEWPQRVLEALAARGIDELLVSPATAHGRRLAEHVREQGAA
                     LRLKGYERAVEAWKDELFFHTPASLTGTLGGIAATGSLVLWPSPQEPRLMSLVPPLHI
                     ALLNASEVRDNLFELMHAQRWTDGLPTNALLVSGPSKTADIQQTLAYGAHGPKELLVL
                     VIEDA"
     gene            complement(11196..12635)
                     /locus_tag="P5537_11265"
     CDS             complement(11196..12635)
                     /locus_tag="P5537_11265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0019516 - lactate oxidation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LutB/LldF family L-lactate oxidation iron-sulfur
                     protein"
                     /protein_id="HRV78663.1"
                     /translation="MSTLADTPAQPIAFTRNAREALADAQLRRNFRGAMDSLMDKRRN
                     QFPDGDELERLRAFGNRVRARALSKLPDLLERLEANLARNGVQVHWAETVEEANAIVH
                     GIAERHAAKKVIKGKSMVSEEMEMNHYLGARGVDCLESDMGEFIVQLREEKPSHIIMP
                     AIHLNAGQVARLFHDKLDVDYTEDVDRLIQIGRETLRRNFFEADIGVSGVNFAIAETG
                     TLLLVENEGNGRMSTTVPPVHIAVTGIEKVVENLRDVIPLLSLLTRSATGQPITTYVN
                     MISGPRKADELDGPQEVHLVLLDNGRSQAFADGELRQTLNCIRCGACMNHCPVYTRIG
                     GHAYGTVYPGPIGKIVTPHMLGLETTRDLPTASSMCGACGEVCPVKIPIPSLLRRLRE
                     EAVRAPAAEPQHMRGQGAKHSKKETLVWKAWRTLNTSPGLYRVAMYAGTRLRGLMPAD
                     IGPWTRYRSAPKPAARSLHELAREHLGAQ"
     gene            complement(12632..13465)
                     /locus_tag="P5537_11270"
     CDS             complement(12632..13465)
                     /locus_tag="P5537_11270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(Fe-S)-binding protein"
                     /protein_id="HRV78664.1"
                     /translation="MSPLSPAPANATRVAPPLEAARRYPPKPADVYLFGTCVIDVFFP
                     GAGMDAIHLLEREGIRVHFPQAQSCCGQPAYTSGYTDEAREVARAQLALFAGDWPVVI
                     PSGSCAGMFRHHYFELFKDEPQTLKQVESLSARTFELAEFLLEVCKVRFEHTGAPVKL
                     ALHTSCSARREMNTHLHGRALLAQLAGVERVEHDHESECCGFGGSFSVRMPDISGAMV
                     QDKTAALKGSGAAEVVSADCGCLLNINGCFEKQGDALRGEHLASFLLRRTASAGTGGA
                     R"
     gene            complement(13594..15291)
                     /locus_tag="P5537_11275"
     CDS             complement(13594..15291)
                     /locus_tag="P5537_11275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate permease"
                     /protein_id="HRV78665.1"
                     /translation="MQPGTLAFLAFSPILLAAVLLVGLRWPAKRAMPVVYFLTAGIGL
                     YVWEMSLNRVLASTLQGLVITVGVLWIIFGAILLLNTLKYSGGITAIRAGFATISPDR
                     RIQAIIIAWLFGCFIEGASGFGTPAAIAAPLLVAIGFPALAAVLLGMLVQSTPVSFGA
                     VGTPIIIGVNSGLDSATIGAQLAAKGSSWDVFLQVITGNVAIIHAMVGTVIPLIMVIM
                     LTRFFGREKSWKAGLEVLPFALFAGVAFTVPYAFTGVFLGPEFPSLLGGLVGLAIVTS
                     AARFGFLVPKKTWDFADPKEWPSEWMGSIEMKLDQLPHHQPISIFRAWLPYVLVGALL
                     VLSRVFPEIGGAMKSVVIVFADILGEKGIKADFQPLYLPGGILVAVVLITVFLHGMHA
                     RSLVKAVGESSRVLLGAGFVLLFTVPMVRILINSGVNAADLPSMPIAMARWVADSVGN
                     VYPLLAPSVGALGAFIAGSNTVSNMMLSQFQFGVATSLGVSTAMIVAVQAIGAAAGNM
                     VAIHNVVAASATVGLLGREGAILRKTFWPTVYYVLMTGAVAMVAIYVLGVSDPLLAG"
BASE COUNT         2541 a         5768 c         5148 g         2375 t
ORIGIN      
        1 tgtggaacac gcgcgcgccg ccacgcagca cctccacgtc cagcatgaag cggtcctcgg
       61 cggtgaaggc gccgtcgagg atctcggcga ggcgctcggt ggccgagctg cgcgcgatgt
      121 cggtaaggaa gccgaggcga ccgagattca cgccgaccag cggcacgcca tgctcgatca
      181 ggcggcgcgc ggtatgcagc atggtaccgt cgccaccgat caccaccgcg aggtccgcgc
      241 tggcaccgat atgctcgtag cttgcgaccg ggaagtcgtg ggcgccgccg atggaactcg
      301 ccgtgccctg ctcgatcaac accgcaaggc cgcgatcgcg caggaagcgg gcgatcgaca
      361 gcaccgactc ggccacgtcg gggctctggt atttgccgat gagggcaagc gtgcgaaatg
      421 gcgtgctcat gggcatcgat taaaccacaa tcgcccgcgc gcgcggcagc accggagccc
      481 ggcgcggcgc cacccagtgg ccagtacgtg cgcgcttcaa tagaatcggc ctctcgaccc
      541 caggcagcca tgaatccgct cgacgcccgc tcccagatcc tcctcaagac cctgatcgaa
      601 cgccacatcg cggacggcca gccggtcggc tcgcgcgcac tgtcgcgcta ctccggcctc
      661 gagctgtcgc ccgccacggt gcgcaacgtg atgagcgacc tcgaggagat gggcttcatc
      721 gccagcccgc acacctcggc ggggcgcatt cccaccgcgc tcggctatcg cttcttcgtc
      781 gactcgctgc tcaccgtgca gccgctcgag aacgcccgcg tgcgcgccct cgagggccag
      841 ctgctgcccg accagccaca gcgcctgatc agctcggcct cgcacctgct ctccgagctc
      901 acccagttcg ccggcgtggt ggtcgcgccg cgcaaggacg cggtacgcat ccgccagttc
      961 gagttcatca gcctggccga gaaccgcatc ctgctgatca tcgtcaccac cggcggcgac
     1021 gtgcagaacc gcctgctgct tacccggcgc gcctacacct cggccgagct ccacggcgcc
     1081 gccacctatc tcaacgaaca cttcgccggt ctgtccttcg aggagatccg ccgccgcgtc
     1141 ggcgacgagc ttcgccagct gcgcagcgac atgagcgagc tgatggccgc caccgtcgac
     1201 gccggctcgg acgccgccga ggacagcgcc acgagctacg tgctgtccgg cgaaaccaag
     1261 ctgctcgaca tcgaggacct gtcgagcaac atgtcgcgcc tgcgcgagct cttcaagctc
     1321 ttcgagcagc gcaccggcct gctccagctg ctcgacctgt ccaaccgcgc cgagggcgtg
     1381 cagatcttca tcggcggcga gtccgggctc gctccgctcg acggctgctc ggtcatcacc
     1441 gcaccgtacg aggtcgacgg tcaggtggtg ggctcgctcg gcgtcatcgg ccccacccgc
     1501 atggcctacg accgcgtgat cccgatcgtc gacatcaccg cccggctgct ctccaacgcc
     1561 ctgtcttcca ggcactgact ccgacgcccg cgcctcactg cgcgtacgaa ccccacccaa
     1621 ggaccacgat gccccgctcc cggcccgaac cgatctaccg ccacgacagc accccgcgca
     1681 ccggcgtgct gctggtcaac ctcggcaccc ccgccgcccc caccgctgcc gcgctgcgcc
     1741 cctacctcaa gcagttcctc tccgacccgc gcgtggtcga gatcccgcgc ctggtatggt
     1801 ggccgatcct caacggcatc atcctcaaca cccggcccaa ggcctcggcg cagaaatacg
     1861 ccagcatctg gaccgacgag ggctcgccgc tgctggtgca cacggtacgc cagaccaagc
     1921 tgctcgccgg ctacctcgcc aaggacggcc acgacgggct cgacgtcgac tacgcgatgc
     1981 gctacggctc gccctcgatc ggcgataccc tggacgcgat gcgcgcgcgc ggctgcaccc
     2041 gcatcctggt ggtgccgatg tacccgcagt attccgcgag caccaccgcc accgtggtcg
     2101 acgaagtcgg ccgcagcctg gcgcagtggc gcaaccagcc cgagatgcgc ttcgtgcgca
     2161 acttccacga cgaccccggc tacatcgacg ccctggtgaa gagcgtgcgc gagcactggg
     2221 cggccaatgg cgagcccgag cgcctgctgc tgagctttca cggcgtgccg cggcgctcgc
     2281 tcgatctcgg cgatccctat cactgcgagt gccacaagac cggccgtctg gtggccgaag
     2341 gcctcggcgt ggcgcgcgag cgcgtgctcg tcaccttcca gtcgcgcttc ggcaaggcgg
     2401 agtggctcaa gccctacacc cagcccaccc tggagcagct cgccgcccag ggcgtgcggc
     2461 gggtggacgt gatgtgcccg ggcttcgtcg ccgactgtct ggagacgctg gaagagatcg
     2521 cgctcgagtg caaggaggct ttcgtggaaa agggcggcca gaccttccac tacatcccct
     2581 gcctgaacga gcgcgacgcc tggatcaggg cgctggcggc gctggtgcgc agccacctgg
     2641 gcaactggct cgagatcgcg ccgcccgacg aagccgcgcg caaggccgcg ctggaacgcg
     2701 cgcgcacact cggcgccgct caataggggc ggggcggcac ccgccggcgg tcggcccggt
     2761 ccgcgaccgg gccgaccgcc gtttcagtaa tcgacgatct gcaggtcgtg cacgaccggc
     2821 gccgcacgga ccgcacgcac cgccgcgggg gcatgcgccg ccatctggcg cgacaccgcc
     2881 gcgagcctgc gcgcggcgac ggtgccgagc tggcgccgga agcgctccag cacttcctcg
     2941 ctggcgagcg cgagcgcggc cgggttgacc tcgagatagc tcagctcgtc gagcgacacc
     3001 gcgctcagca gctgcctgtg ctcgagctgg tcgagccagg cctgctcgcc gaagacctcg
     3061 cccggcccca cctccagcac ccggcggccc tcgatcgaaa gctccacctt gccctcgagc
     3121 acgatgccga agcgctggtc gatgtcgccc tcgcgcatca acccgagatc gctgccgacc
     3181 ttgcgccagg cgcagatccg catcacctcc cacaggtcga cgtcctcgaa ctcggtgaag
     3241 aaggcgagct tgcgcaggcg cgcgaagcgc tcggcgtcat ggtgcacgtg gccttcgtcg
     3301 aggatctggt agcgcaccgc ggcgaggtcc ttggcgaact cggcgccatt gcggtagcgc
     3361 gagtacagat ccttctcgag cgccttgcgg attaccgcgt ccatctgctc gggcacgtcc
     3421 gggttgagct gcgagaccga gggcggatcg gcattgatga tcttgtagac gagttgggcc
     3481 ggattgttcg cgcggaaagg cagccgaccg gtcaacatgt ggaagagcag cacgccgagc
     3541 gaatacaggt cggtcttctg gttgagcgga tagcccttga tctgctccgg gctcatgtag
     3601 gccggcgagc ccacgcccat gatgaaggtc gagtcggtgt cgagcttctt gttgatgttg
     3661 agcgcgaggc cgaagtcggt gatcttcacg ttgtcctgct cgtcgaccag gatgttcgcc
     3721 ggcttgatgt cgcggtgcac gatgccctgg cggtaggcgt ggtcgagcgc catgcagcac
     3781 ttgaaaatga tcccgatcgt gcggtggatc ggcagcaggt tctggaagct gcagtagcgc
     3841 tcgagcgagc cgccggggaa gtactccatc accacatagg cctggtcggg ctcgatcgag
     3901 gcgtcgtgga tacggatgat gttggggtgg tcgaggcggc cggacaccac gcgctcggcc
     3961 ttcagcagct tgatcaggcg gcggttccac ttcgcctcgt cgcgcgcctt gtcgtcgaag
     4021 cgcacgtgct tgagcgccac cggctcgggg tagtccgggg actcggcgag atagaccacc
     4081 gcggtcgcgc cgcgaccgat ctccttgatg atcctgtact tgccgatgcg ttcgggaatc
     4141 cggttcatgc tgtcttgcga ggctcgggcg cccgcgcggg cggcaggcat cggcgcgatt
     4201 gttgcacgat ccggcgccgg cgtgcgctcc ccggcccccg gccacgcggg attgtccgcc
     4261 gcggcccgtg catgcttgaa tgaggcccgt cccgcaaccg ccccccgagg agcccgcctt
     4321 gagcgaagcc gtcgacctgc tgatcaacgc ccgctggatc gtccccgtcg atccgcacga
     4381 agccgtgctc gccgaccacg cggtcgcggt ccgcggcgga cgcatcgtcg acctgctcgg
     4441 ccaggacgcg gcgcgcacgc gctacgccgc ggacaaggtg gtcgagctgc cccagcacgt
     4501 gctgatcccg ggcctggtca acctccacac ccatgccgcg atgagcctgc tgcgcggcat
     4561 cgccgacgac ctgccgctga tgcgctggct gcaggaggcg atctggccgg cggagagccg
     4621 ccacgtcagc gcggctttcg tgcgcgacgg caccctgctc gcagcggccg agatgatccg
     4681 gggtggcatc accacctgca gcgacatgta cttccatccc gaggccgcgg cggaagcctt
     4741 cgccgcggcg ggcatgcgcg cggtcgtggg cgcggtcgcg ctggagttcc ccacctcgta
     4801 cgcgagcgac cccgatgact acctgcgcaa gggactggcc gcacgcgacc gctggcaggg
     4861 ccacccgctg ctcggcttct cgatcgcccc gcacgccccc tacaccgtct cggacgagag
     4921 cttccgccac gtgcagacgc tcgccgacga gctcgagctg ccgatccatg tgcacatcca
     4981 cgagaccgcg caggagatcg ccgactcgct cgccgcccac ggctgccggc ctctcgcgcg
     5041 cctcgcccgc ctcggcgtgc tcggcagcaa cctcatcggc gtccatgcgg tgcacgtcga
     5101 cgaacccgac atcgagctcc tcgcccgcca cggctgcagc gtcgcccact gccccacctc
     5161 gaacatgaag ctcgccagtg gcatcgcgcc ggtgccgcgc ctgctcgccg ccggcatccc
     5221 ggtcggcctc ggcacggacg gcgcggcgag caacaatcgc ctcgacctgc tccaggagat
     5281 gcgccacgcc gcgctgctcg ccaaggtagg cagcctcgac gccaccgcct tgccggcaca
     5341 cgcggccctg cgcatggcca cgctcgacgg tgcacgcgca ttgggcatgg acgatcgcat
     5401 cggctcgatc gaaataggca aatgcgccga tctttgcgcc ctcgagcttt ccgcaccgca
     5461 atgccgaccc tgtttcgatc cggtgtcgca tctggtctac gtctgcggtc gcgaaaatgt
     5521 ctctcatgtc tggatcgggg gtgaaacccg cgtggacaaa ggcatctcgc tgttgcatat
     5581 taacgacacc gaattgctcc ggctcgtgtc gatgtggcaa actaggctcg gtaattgaac
     5641 tggatatact ggtacaaacc gacacgaaga cggcagattc gccagtcttc atttcgttca
     5701 gtggcaattc cggcgactcg cccttcaaag aggaaaccat gatcaaacaa tccaagaagc
     5761 agatgctcat gctggccgcc atcgcctcga tcggcctgtc cgccccgagc gctttcgctc
     5821 aggtcaacga cgtcgtcgtc gccggcaagg gtgaaatccc ctacgtgatc gacgcgcgca
     5881 acgtcgtcgc tcgcagcggt accggcctgt gctggcgcac cggctactgg agccccgccg
     5941 ctgcctcgac cgcgatggcc ggcgagttcc cggtcggctg cgcttgcgac aaggacatcg
     6001 tccccgccga caagtgcacc gtgaaggctg ccgctgccgt gcccgcgccg aagcccaccg
     6061 ccgacaaggt caagctgtcg gccgacgccc tgttcgactt cgacaaggcc gtcctcaagg
     6121 ctgaaggcaa ggccaagctc gaccagctcg ccgcccaggc caagtcgctc aagctggaag
     6181 tgatcctcgc cgtcggccac accgaccgcc tgggttcgaa cgcctacaac cagcgcctgt
     6241 ccgagcgtcg cgccgccgcc gtcaagacct acctggtctc gaagggcgtc gatgccaacc
     6301 gcgtctacac cgaaggcaag ggcgaaaccc agcccgtgac cggcaacaag tgcgacaagg
     6361 tcggtggtcg cgccgcgcag atctcctgcc tgcagccgga tcgtcgcgtc gaagtggaag
     6421 tcatcggctc caagtaatcc tcgagccggt aacccgaaag ccctgcctcg gcggggcttt
     6481 ttcgtttgtg ccgggtgcgc gtgcacccgg cgcgcgctag caaggacttt cgaagccatg
     6541 aacaccgtca acgccgaccc cgccgaactg cagaaattca gcgacctcgc ccaccgctgg
     6601 tgggaccccg cctccgagtt ccgcccgctg cacgagatca acccgctgcg cctgggctgg
     6661 atcgacggca aggccgcgct cgccggcaag aaggtgctcg acatcggctg cggcggcggc
     6721 atcctcgccg aaggcatggc ctcgctcggc gccgaggtca ccggcatcga cctgtccgag
     6781 aaggcgctca gcgtcgcccg cctgcatctg ttcgagagcg gccacaaggt cgactaccgc
     6841 cacatgagcg ccgaggcgct cgccgacgaa ctgcccgggc acttcgacgt cgtcacctgc
     6901 atggagatgc tcgagcacgt ccccgacccg gccagcatcg tcgccgcctg cgcgcggctg
     6961 gtgaaacccg gcggccacgt cttcctgtcc acactcaacc gcaacccgaa gtcctacctg
     7021 ttcgcgatca tcggcgcgga gtacctgctc aagctcctcc ccgccggcac gcacgaatac
     7081 gcgcgcttca tcaagccctc cgagctcagc cgtcactgcc gcaatgcgcg cctggacgtg
     7141 caggagatca tcggcctgtc ctacaacccg ctcaccaaga cctactcgct cggccgcgac
     7201 accgacgtga actacctcat ccataccgtc gccgcgggct gaaccgcgca cgcaccggca
     7261 tcgacgccga atgccgcgcc ggggcgtgct caccgaagag gccgcaattc agttcatgca
     7321 tgcagcttga gcgtgcatta aactgcaggc gagcgattcc tccacgggga gcaaggcgat
     7381 gagcttccgc cacctgaaaa gcctgttcaa tccgcgctcg atcgccgtga tcggcgcgag
     7441 cgcgcgcgag cgtcgcatgg gcaacgtcct catgcgcaac ctgctgtcgg gccagttcgc
     7501 cgggccgatc atgccggtca atcctcggcg cccctcggtc gccggcgtac tcacctatcc
     7561 gagcgtcgcc gccctgccgc agacgcccga cctggcaatc gtctgtaccc ctgccccgct
     7621 cgtaccgcgc atcgtcgagg aactcggcga acgcggcacg cgcgcggtga tggtgatggc
     7681 caaccagctc gacaccacac tcggcgccga cggccgcccg ctcgagcgca gcatcctcga
     7741 gatcacccgc cgccacgaga tgcgcctgct cggcggcagc acgctcggca tcctggtgcc
     7801 cgggctcggc ctcaacgcca ccttctcgca gatcgccgcg cgcccgggca agctcggctt
     7861 cgtctcccag cgcgacacgg tcggcaccat ggtgctcgac tgggcgctgc gcaagaaggt
     7921 cggcttctcg cacttcgtct cgctcggcga cagcctggac atcggcttcg gcgaggtact
     7981 cgacttcctc gccgcggact cgggcacacg cgcgatcctg ctctacatcg agtccatcca
     8041 ggaccgccgc gcctttatgt cggccgcgcg cgccgccgcg cgcaacaagc cggtgatcgc
     8101 gatcaaggcc gggcgctcgc ccaacaaccc gctgatgggc gtctccgacc cgctcttcct
     8161 cgagatgccc aacctggtca gccacgacga cgtgcacgac gccgcgctgc gccgcgccgg
     8221 catcctgcgg gtggaccagc tcgaggagat gttcggcgcc gccgagaccg tgctgcgcgc
     8281 ccgcccgctg cgcggcaacc gcctcgtcgt gctgagcaac ggcggcggtg ccggcctgat
     8341 ggtggaggac agcctctacc tcgccggcta cagcctgccg tcgctcaagg agcagaccat
     8401 cgagcgcctg cgccgcttca tgtcgccggg ctggaacggg cgcaatccgc tcgagatccg
     8461 cgtcgactcc gagccggcct gctacgagcg cctgctcaag atcctgcagg aagagcgcga
     8521 cggcgacgcc gtgctgctca tccacactcc aaacgcgctc tcgagcagca tggacaccgc
     8581 gcagcaggtg atcgccaccg cgcgcgagac cggcatcaac ctgatgacct gctgggtcgg
     8641 cgacgagagc gtggagaagg agcgcaacct cttcatcaac gcaggcatcg ccaccttcga
     8701 ctcacccgag catgcggcca gcgccttcct gcacatgcac cgccaccgca tcgcctccga
     8761 ggtgcttatg gaggtcccga cctccgaacc cgaggcgttc aagcccgacg tcgcgcgcgc
     8821 ccgcgcggtg atccagggcg cgctcgccga atcgcgcgcc agcctgaccg aatccgaatc
     8881 caaggacgtg ctcgcggcct acggcgtgcc ggtcatccag acccacctcg ccgccagccc
     8941 ggaagaggcc gcgcagatcg ccggccgcat cggcctgccg gtagcgctga ccctgatgtc
     9001 gcgcgacatc cgccgcaagt gggacgtcgg cggcgtcgcg ctcaacctcg agagcaccga
     9061 ggcggtcgag gtcgccgcgc gcggcatgat cgagcgcgcc gggcgcgccg agccgccggt
     9121 gtcggtgagc ggcttcaccg tgcagcgcat ggtgatgcgc ggccatgcgc gccagctgct
     9181 gatcggcgtc agcaccgacc gcctgttcgg accggtgatc gtgttcggcg agggcggccg
     9241 cgcgctggag atcttccgcg gcctcgcagt cggcctgccg ccgctcaaca agccgctcgc
     9301 cgacgatctc atcgcccgca gcaaggcggc ggcgctgctc gaggcgcgcg gccacctgcc
     9361 cgcggccgac cgcgacgcgc tcgcgctcac cctcaccaag gtctcgcaga tcgtcgtcga
     9421 ccatcccgag atccacgaga tggacatcaa cccggtgttt gtcgacgagc acggcgtgca
     9481 ggccctcgac gcccacatgc gcctgcgccc ggccaccgcc cacgagcacc ggctggccat
     9541 ccagccctat ccgaaggcgc tcgaggagcc ctcgcagctg cgcgacggcc gcccgatcct
     9601 gctgcgcccg atccgccccg aggacgagcc ggcgcactac gccttccttt cgcgcctcac
     9661 ccgcgaggac ttcatctacc gcttcttcaa ctacatcccc gagtttccgc gccgcgagat
     9721 ggcgcgcctg acgcagatcg actacgaccg cgagatggcc ttcatcgcca ccgccaccgg
     9781 ccccgacggc aagcccgaga ccctgggcgt gtcgcgcgcg gtggccgacc cggacaacca
     9841 caccgccgag ttcgccctcg tcatccgctc cgacctcaag cgccagcgcc tgggctcgat
     9901 cctgatggac aagctggtgc gctacgcgcg cgagatcggc atccagcgcc tcgtcggcga
     9961 ggtgatgggc gaaaacgagc cgatgctcgg gctattgaag cacctcggct tcaagctcaa
    10021 ggcctcggag gagcctgggg tggtgcgggc gatcttcgag ctgcgcccgc cgtcggaggc
    10081 gtgaggggcg gacaccgggg ctgcgcgcca aagatctacg cccagggtgg atcaagccgc
    10141 cgcattcgcg cctgccggcg ctcctacagg aaccaccgcg cgtccccgcg ctcccacacc
    10201 ccccaccgcg cgtccccgcg cttccgcatg aaccgccgcg cgtccgggcc gcgcccgtag
    10261 gagctgcggc agctgcgaac ccgacggtcc ggcgatggac gcgcgtgcag ggcttcaccg
    10321 ccgcattcgc gcctgccggc gctcctacag aaaccaccgc gcgtcccggc gctcccacac
    10381 acaccaccgc gcgtccccgc cgccgcgcgt cccggccccg cctgtaggag ctgcggcagc
    10441 tgcgaaatcg gcgctcgagc aagcgcggtg gcgcctcgaa agcgcggcgg cacgcgacgc
    10501 tcaggcgtcc tcgatcacca gcaccagcag ctctttcggc ccatgcgcgc catacgcgag
    10561 cgtctgctgg atgtcggcgg tcttcgacgg ccccgacacc agcaaggcgt tggtcggcag
    10621 gccgtccgtc caacgctgcg catgcatgag ctcgaagagg ttgtcgcgca cctcgctcgc
    10681 gttcagcagc gcgatgtgca gcggcggcac caagctcatc aggcgcggct cctgcgggct
    10741 cggccacagc accaggctgc cggtggcggc gatgccgccg agcgtgccgg tgaggctggc
    10801 gggcgtgtgg aagaagagct cgtccttcca cgcctccacc gcgcgctcgt agcccttcag
    10861 ccgcagcgcg gccccctgtt cgcgcacgtg ctcggccagg cggcggccgt gggcggtggc
    10921 gggcgacacc agcagctcgt cgatgccgcg cgcggcgagc gcctccagca cgcgctgcgg
    10981 ccactccgcc gcggtggtca gcaaggtctc gccatgcacc gcctcgagca tgcggcgcag
    11041 gcgcgcgatg cgctcgtccg ccgcatagcg ccagggatcg gtgaccaggc cgatgtcgta
    11101 gtcgtcggcg accgcggtcg tgcccgcgag gctggcgcgc agcttgccga ggatccgttc
    11161 tttcgcattc attcgggttt cgctcctggc gtcgttcatt gcgcgcccag atgctcgcgg
    11221 gcgagctcgt gcaggctgcg ggcggccggc ttcggtgcgc tgcggtagcg cgtccacggc
    11281 ccgatgtcgg ccggcatcag cccgcgcagg cgggtgccgg cgtacatcgc cacgcggtac
    11341 aggcccggcg aggtgttgag cgtgcgccac gccttccaca ccagggtctc cttcttcgag
    11401 tgcttggcgc cctgccctcg catgtgctgc ggctcggcgg caggcgcgcg caccgcctcc
    11461 tcgcgcaggc ggcgcagcag cgaggggatg gggatcttca ccgggcacac ctcgccgcag
    11521 gcgccgcaca tcgacgaggc cgtgggcagg tcgcgggtgg tctccaggcc gagcatgtgc
    11581 ggggtgacga tcttgccgat cggccccgga tacaccgtgc cgtaggcgtg gccgccgatc
    11641 cgcgtataca ccgggcagtg gttcatgcac gcgccgcagc ggatgcagtt gagcgtctgg
    11701 cgcagctccc cgtcggcgaa ggcctggctg cggccgttgt cgagcagcac caggtggacc
    11761 tcctgcgggc cgtcgagctc gtcggccttg cgcgggccgg agatcatgtt gacgtaggtg
    11821 gtgatcggct ggccggtggc cgagcgcgtc agcagcgaca gcagcgggat cacgtcgcgc
    11881 aggttctcga ccaccttctc gatgccggtg acggcaatgt gcaccggtgg caccgtggtc
    11941 gacatgcggc cgttgccctc gttttccacc agcagcagcg tgccggtctc ggcgatcgcg
    12001 aagttcaccc ccgagacgcc gatgtcggcc tcgaagaagt tgcgccgcag cgtctcgcgc
    12061 ccgatctgga tcaggcggtc gacgtcctcg gtgtagtcga cgtcgagctt gtcgtggaac
    12121 agcctggcga cctggccggc gttgaggtgg atcgccggca tgatgatgtg cgagggcttc
    12181 tcctcgcgca gctgcacgat gaactcgccc atgtccgact cgaggcagtc gacgccgcgc
    12241 gcgccgaggt aatggttcat ctccatctcc tcggacacca tggacttgcc cttgatcacc
    12301 ttcttcgccg catggcgttc ggcgatgccg tgcacgatgg cgttggcctc ctccaccgtc
    12361 tccgcccagt gcacctgcac gccattgcgg gcgagattgg cctcgaggcg ctcgagcagg
    12421 tcgggcagct tcgacagcgc gcgtgcgcgc acgcggttgc cgaaggcgcg caggcgctcg
    12481 agctcgtcgc cgtcgggaaa ctggttgcgg cgcttgtcca tcagcgaatc catcgcgccg
    12541 cggaagttgc gccgcagctg cgcgtcggcg agcgcctcgc gcgcgttgcg ggtgaaggcg
    12601 atcggctgcg cgggggtgtc ggcgagcgtg ctcatcgtgc acctcccgtg cccgccgagg
    12661 ccgtgcggcg cagcaggaag ctcgccaggt gctcgccgcg cagggcgtcg ccctgcttct
    12721 cgaagcagcc gttgatgttg agcaggcagc cacagtcggc actcaccacc tcggccgcgc
    12781 ccgagccctt cagcgccgcg gtcttgtcct gcaccatcgc gcccgagatg tcgggcatgc
    12841 gcacgctgaa gctgccgccg aagccgcagc actcgctctc gtggtcgtgc tccacgcgct
    12901 cgacccccgc cagctgcgcg agcagcgcac gcccatgcag gtgggtgttc atctcgcgcc
    12961 gcgccgaaca ggaggtgtgc agcgcgagct tgaccggcgc gccggtgtgc tcgaagcgca
    13021 ccttgcacac ctcgagcagg aactcggcga gctcgaaggt gcgcgcggac agcgactcga
    13081 cctgcttcag cgtctgcggc tcgtccttga acagctcgaa gtagtgatga cggaacatgc
    13141 ccgcgcacga gcccgacggg atcaccaccg gccagtcgcc ggcgaagagc gcgagctgcg
    13201 cgcgcgccac ctcgcgcgcc tcgtcggtgt agcccgaggt ataggccggc tggccgcaac
    13261 agctctgcgc ctgcgggaaa tgcacccgga tgccctcgcg ctcgaggagg tggatcgcgt
    13321 ccatccccgc accgggaaag aacacgtcga tcacgcaggt gccgaacagg tagacatcgg
    13381 ccggcttggg cgggtagcgg cgcgcggcct cgagcggcgg cgcaacgcgc gtggcattgg
    13441 cgggtgcagg ggacaggggg ctcatgtgcc tgggctccgg ggttgctggg ttctggattg
    13501 cagggatctg gaatgcactg cagccgcggc caggcctcga ctgcaggagg gacggccgcg
    13561 cgggggatgc cggagccccc cccgctgcgg cgctcagccg gcgagcagcg ggtcggacac
    13621 gccgaggacg tagatcgcga ccatcgccac cgcgccggtc atcagcacgt aatagaccgt
    13681 cggccagaag gtcttgcgca ggatcgcgcc ctcgcggccg agcaggccca cggtcgccga
    13741 ggccgccacc acgttgtgga tcgccaccat gttgccggcg gccgcgccga tcgcctgcac
    13801 cgccacgatc atcgccgtgg acaccccgag cgaggtcgcc acgccgaact ggaactgact
    13861 cagcatcatg ttgctgaccg tgttcgagcc cgcgatgaag gctccgagcg cgcccaccga
    13921 gggcgccagc agcggataca cgttgcccac gctgtcggcc acccagcgcg ccatcgcgat
    13981 cggcatgctc ggcaggtcgg cggcgttcac ccccgagttg atcaggatgc gcaccatcgg
    14041 cacggtgaac agcagcacga agccggcgcc gagcagcacg cgcgaggact cgcccaccgc
    14101 cttcaccagc gagcgcgcgt gcatgccgtg caggaacacg gtgatcagca ccaccgccac
    14161 caggatgccg ccgggcaggt agagcggctg gaagtcggcc ttgatgccct tctcgcccag
    14221 gatgtcggcg aacacgatca ccaccgactt catcgccccg ccgatctcgg ggaacacccg
    14281 gctcagcacc agcagcgccc ccaccagcac gtagggcagc caggcgcgga agatgctgat
    14341 cggctggtga tgcggcagct ggtcgagctt catctcgatg ctgcccatcc actcgctcgg
    14401 ccactccttc gggtcggcga agtcccaggt cttcttcggc accaggaagc cgaagcgcgc
    14461 cgcgctggtg acgatggcca ggcccaccag gccgcccagc agcgagggga actccggccc
    14521 caggaagacg ccggtgaagg cgtacggcac ggtgaaggcg acccccgcga agagcgcgaa
    14581 gggcagcacc tcgaggccgg ccttccagct cttctcgcgg ccgaagaagc gggtgagcat
    14641 gatcaccatg atcagcggga tcaccgtgcc gaccatggca tggatgatcg ccacgttgcc
    14701 ggtgatcacc tgcaggaaga cgtcccagct cgagcccttg gcggcgagct gcgccccgat
    14761 cgtcgcgctg tcgaggccgc tattgacgcc gatgatgatc ggcgtaccca ccgcaccgaa
    14821 ggacaccggc gtgctctgca ccagcatgcc gagcagcacc gccgccagcg ccgggaagcc
    14881 gatcgccacc agcagcggcg cggcgatcgc cgccggcgtg ccgaagcccg acgcgccctc
    14941 gatgaagcag ccgaacagcc acgcgatgat gatcgcctgg atgcggcggt cggggctgat
    15001 cgttgcgaag cccgcgcgga tcgcggtgat gccgcccgag tacttcagcg tgttgagcag
    15061 caggatggcg ccgaagatga tccacagcac cccgaccgtg atcaccagcc cctgcagggt
    15121 cgaggcgagc acgcggttga ggctcatctc ccacacgtac aggccgatgc ccgcggtgag
    15181 gaaatagacg accggcatcg cgcgcttggc gggccagcgc aggcccacca gcaacaccgc
    15241 ggcgagcagg atcggagaaa aggcgaggaa tgcgagcgta cccggctgca tgggagcccc
    15301 cgcctcagac cggcgcgcgc atcgtgcgcg ccgccatgaa catcgatcga accatcattg
    15361 ccccttcccc cttcggatgg atttcatgaa atctggatga gtgtgccttc gtctttccgg
    15421 taaattggta ataccacttt accggaagtt gcaccagcct aagggagccc gcgaggcatg
    15481 tcaatgcaaa tcatcagatt tatcgatggg aacatgaggg gcgggttcgg cgggcgccgg
    15541 gaggggggcg ggcggtggtt ctgttccaca cagtcgctgc tccgatgatg cgccgcatcg
    15601 cgcgcgggga actgccggac tcggtgccgc ccaccggcca gctcgcgcga gtcggaggca
    15661 ggtcggcagc gccatgcata tatacttttc cggcaatgcc atttgcttca cccggagacc
    15721 gatctgcgat gcacgaaatc tcgccatccg acctcaagac catcctgcac tccaagcgcg
    15781 gcaatgttcc atgtagtaaa ggttggcgcg cttggagtgc aggatggtct tg
//
LOCUS       DAOTIN010000073        14894 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_4824_length_14894_cov_9.185255, whole genome shotgun sequence.
ACCESSION   DAOTIN010000073 DAOTIN010000000
VERSION     DAOTIN010000073.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 14894)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 14894)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14894
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4824_length_14894_cov_9.185255"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(153..1211)
                     /locus_tag="P5537_11280"
     CDS             complement(153..1211)
                     /locus_tag="P5537_11280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78666.1"
                     /translation="MKVAAFSVELQSSHRFSQSLETRERLEVWRGTPDAGPAAAGVPR
                     PAVEISAAAQSALATESETAAVDALADDAVEDDPRLAMLIRMIEFLTGEPVRRFSMRD
                     LQPADTAAESGYETGGNAVASGQGGARRVGFGLEYDFSSRFSETETVSFAAAGVVRTA
                     DGGEIRFELGFEMSRSHTESVSVSVRAGDQRLKDPLVLDFGGPAAALSDVRFDFDLDG
                     DGSREKLPLMSGSGFLAFDRNANGRIDDGRELFGPATGDGFAELAGLDDDRNGWIDEA
                     DAAWSQLRVWQPDAAGKGSVRSLGEAGVGALHLGRVATPFSLKDAANDTQGLMRASGV
                     YLREDGRAGTLSQVDLKV"
     assembly_gap    1584..1683
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(1684..3072)
                     /locus_tag="P5537_11285"
     CDS             complement(1684..3072)
                     /locus_tag="P5537_11285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase/DUF3482 domain-containing protein"
                     /protein_id="HRV78667.1"
                     /translation="MNDILRVAVVGHTNTGKTSLLRTLARDVGFGEVSDSAGTTRHVE
                     GLRLMADGVAAAELFDTPGMEDAIALLEFIDELVDPGERVDGPERVARFLARDEAAGR
                     FEQEAKVLRQMLASDAALYVVDARDPVLPKHRDELELLAACARPLLPVLNFIADPAAR
                     ADDWRGALARLGLHAVVSFDTVAPPLDGERELFDTLATLIHSHRGRLQALIEARAREA
                     AARREAARRLVAELLVELAARRDRLADSEDDDAALQVAVERLRADVRSREQACVDALL
                     RLYRFRADDARMADLPLADGRWDDDLFNPETLRQMGVRLGTGAAAGAAAGVGIDLMTG
                     GLTLGAAAALGAIAGGLWQTFGHYGERLAAKLRGHRELTVDDAILRIVALRQRRLLVA
                     LDGRGHAAVKPIELDAGREGAAVNADPVSARWRKDALPEAIGRARAHPEWAEADGSHK
                     DEAIAELARALA"
     gene            complement(3069..4523)
                     /locus_tag="P5537_11290"
     CDS             complement(3069..4523)
                     /locus_tag="P5537_11290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002930630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2868 domain-containing protein"
                     /protein_id="HRV78668.1"
                     /translation="MPTSFPPNSLSLRWLAELVRRHEERHPPLDEARAHAEARAVAGD
                     LEARVLRRAAVLEAASGWREAIRRWQGRARLVLVLAFALAFAFGFGAAAGALGDGTRP
                     VNVVWTLGGLLGVHLLSLLLWLASLGLQGRAQGDALHHGGLLGRAWLAVTGWLDRSRE
                     AADLPLALGGLLGGGRTAAWGVGAANHALWCGALAGATLGVLALLATRRYGFVWETTI
                     LPADSFVALSAALGALPGMIGFPVPDAATVLASGDAPMLDEAGRRAWAGWLVGAMTIY
                     GVLPRLALALLCFWLWRRATAAIVLDLGRPGYARLRPLLMPDSERIGVRDPEPAAMPH
                     PQRHAAVAHGDGGAVAVAIELGDDLAWPHALAAADDATAVPAWEDGGRLDSREQRRGA
                     RARFAAHPPVRLVVAVDARQTPDRGSLGLIAELADHAQATRVWLAGIDAAAEQAGRLR
                     QWREGLAGIGLGEAAVLVDARAAWVWLERGDEVR"
     gene            4733..5209
                     /locus_tag="P5537_11295"
     CDS             4733..5209
                     /locus_tag="P5537_11295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriohemerythrin"
                     /protein_id="HRV78669.1"
                     /translation="MSTELFHWTDEFSIGLQEIDEQHKELVELLNQLHVAIKEHHGSA
                     TSRQILDKLADYTRTHFAVEESLMRVSNYPEFATHKQNHEDLIAQVKALQDKLDSGQA
                     TITFELLHFLKVWLTRHINEADKRFGAFFLEAGGASRWSDHVEDAMKKRKWWWKFW"
     gene            5295..5786
                     /locus_tag="P5537_11300"
     CDS             5295..5786
                     /locus_tag="P5537_11300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004385227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78670.1"
                     /translation="MTMPLTTRARSALLALALPAALFAGAAHAETLSCPALDKAVQVA
                     ACPSDAELQYTFMGFCGDNARLYGRDVFTCATFENYKAVKNTALWESENGSFSGYLNC
                     NLDTATLRASRALKMSVEKKNGLTRLICDYENDQRMVMRTKGTCTVEAADCSSGECRA
                     SCE"
     gene            5812..6333
                     /locus_tag="P5537_11305"
     CDS             5812..6333
                     /locus_tag="P5537_11305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004385228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HRV78671.1"
                     /translation="MTNTPAPGASSPVRQKTAASEARGARLLVGLIGGAFLLLIAAFV
                     SMIFLAQGEVRLNAVGPIAAAPGAERGGVVFHGTANIWEVRGRLTQDDARQVSLAIDL
                     VGPTAQPAPAGLQLSLSLERADGTGTPIPLDHRLVRPGSLVATSAPLETGQWRLRLTL
                     PEIEALQEFSVEP"
     gene            complement(6372..7541)
                     /locus_tag="P5537_11310"
     CDS             complement(6372..7541)
                     /locus_tag="P5537_11310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015433949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HRV78672.1"
                     /translation="MSAASTPSADADRRIPVTLLTGFLGAGKTTLLNHLLRQPQMDGS
                     AVLINEFGAVGVDHHLVEKVDESLVVLDSGCICCSVQGDLVRALKGLFMRALRRELKG
                     LRRVLIETTGLADPAPVIHTLMAEPFLSERYRLDGVVTAVDVTHALDQLGAHNEAVRQ
                     VAMADRLLLTKCDLASAGQRAAVAAGIARLNPGARQVEVAGGAVAADAVFGCGLYDPT
                     GKLPDVAAWLGEEAVRAARQAPAAPVWSRARAQKSAPTHGAGAPADAESAESAASAAP
                     ARHDAGVTSFVLRFDEPLDWFGFSDGLALLLQVYGGRILRIKGLLNVAGDPLPRVLQC
                     VQHSVYPGSSLPAWPAQPPYDDRRSRLVFIVRDLAQDEVVSILGSFVGQVPQVGD"
     gene            complement(7599..9032)
                     /gene="adeC"
                     /locus_tag="P5537_11315"
     CDS             complement(7599..9032)
                     /gene="adeC"
                     /locus_tag="P5537_11315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AdeC/AdeK/OprM family multidrug efflux complex
                     outer membrane factor"
                     /protein_id="HRV78673.1"
                     /translation="MTPHETRRPLRGLVVALAATTLGACTTLIPGFERPVAPVPASFP
                     QAQPTPAATDAVAPAVDTLAWRDYFADVRLQRTIELALANNRDLRVAALAIERARAQY
                     GIQRADLFPSLAVSGGQSAQRVPGDLSMSGDSTVSRQYSANLGFASYELDFFGRVRSL
                     EEQALQTYLGTEEARRSAQISLVAEVANAWLRLAADRERLALARDTFETRKKSFELTR
                     RSFELGAVSGLELRQSETLMQTARADAARYAALVAQDENALALVAGGAVPAELQPQAI
                     GERVAAVAELPAGVPSEVLARRPDVAQAERALMAANASIGAARAAFFPRITLTATAGS
                     ASSSLDGLFDGGSGAWSFVPQIRLPIFEAGRLQASLDVAEIQRDIQIAQYEKAIQSAF
                     REVADALAERATLAEQLDARRSLVAAAKKSFELSEARYKGGVDSYLNLLDAQRSLYGA
                     ELELIGTRLADATNRVALYKALGGGWQ"
     gene            complement(9034..12189)
                     /locus_tag="P5537_11320"
     CDS             complement(9034..12189)
                     /locus_tag="P5537_11320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0042908 - xenobiotic transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HRV78674.1"
                     /translation="MARFFIDRPIFAWVIAIVIMLAGALSIQQLPVSQYPSIAPPAIV
                     INAKYPGASAKAVEDSVTQIIEQKLTGLDGLLYMKSTSDAYGNASTTLTFSADTDPDI
                     AQVQVQNKMQTALPLLPQAVQQQGVTVAKSAMNFLMVVGFVSADNSMTGTDLSDFLVS
                     SVQDPLSRVDGVGEVQVFGAQYAMRVWIDPARLTNYRLTPGDVRAALMAQNTQVSAGQ
                     LGGTPALPGQGFTATITAQSRLQTVQEFEDILLRSSTQGGEVRLKDVARVEIGAENYG
                     TVARFNGQPAAGVGIRLASGANALDTATAVRTRLDEMKRYFPEGVEYVVPYDTTPFVK
                     ISIESVVMTLIEAVVLVFLVMYLFLQNFRATLIPTMAIPVVLLGTFGLMAAFGFSINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVMTEEGLPPKEATKRSMDQITSALVGIGLVLS
                     AVFVPMAFFGGSTGVIYRQFSITIVSAMALSVLVAIVFTPALCASILKPVEKGHEHGE
                     GGLFGRFFHWFNVRFERSTQGYESAVGGILKRSVRFLAIYLAIVAVLGLLFVRMPTSF
                     LPEEDQGVMFNQVMLPAGATQERTLEVLKKVEHHFLENEKDTVRAIFTVAGFSFGGSG
                     QHMGIGFVNLKHWDERKAPGKDVKSVAGRAMGAFAQIREAMVFAFVPPAVIELGTSGG
                     FTVQMQDRSGLGHDALLAARNQFLGMAAQDKRLVGVRPNGQEDMPELKLDIDHAKAGA
                     LGLSVADINDTLSTAWGGSYINDFLDRGRIKKVYLQGDAGSRMTPEDLDKWYVRNKAG
                     DMVPFSAFATAHWTYGSPRLERFNGQPSMELLGQAAPGLSSGEAMQAVEEIMAKLPPG
                     IGYDWSGTSYEERRSGSQAPALYALSLLVVFLCLAALYESWSVPFAVMLVVPLGVLGA
                     LLAASGRGLSNDVYFQVGLLATIGLSSKNAILIVEFAKAQMEEGKDLISATLAAVRMR
                     LRPIIMTSLAFGFGVLPLAIATGAGAGSQNAIGTGVLGGTIGATLLGLFFVPLFYVVI
                     KRIFPDKPQEAAVAPSAQEGR"
     gene            complement(12201..13403)
                     /locus_tag="P5537_11325"
     CDS             complement(12201..13403)
                     /locus_tag="P5537_11325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HRV78675.1"
                     /translation="MKIRSQSRYRAAAMVTLGALLLAACSGGKEQGAAPGAGGPPPAP
                     AVTVMTVASGSVPMVTELPGRTTPYLIAELRPQVTGILTQRAFDEGSEVKAGQVLYRI
                     DDAPYQAAHDSARAALARAEANAQVARIKAERHAGLVKIEAVSKQANDDAQAALKQAQ
                     AEVAAAKAALDKARIDLDYTRLKSPIAGRIGRSAVTPGALVTANQAQALATVQQLDPI
                     YVDLTQSSADLLRMRAEIAAGRLQAGARGEVPVKLVLEDGSEYAAEGRLALSEVTVDA
                     GTGSVTLRAKFPNADGVLLPGMYVRARLPQGTRSEAILVPHKALSRDPLGNALVMVVD
                     AESKVEARPVKVAQSLGSDWVVTGGLAAGERIIVEGLQKARPGSPVQAQEAGAGAPPA
                     AAPAAKAS"
     gene            13601..14224
                     /locus_tag="P5537_11330"
     CDS             13601..14224
                     /locus_tag="P5537_11330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004360219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HRV78676.1"
                     /translation="MQTPDSSPHLIDAPRAAARRQQILHAAAQCFREHGFHGASIALI
                     SKTAGMSPGHIYHYFENKEAIIAAIVAQDLESLLTLTTELRAACNVRAALIERAAEGV
                     ADQLDPAGAALKLEIVAEAARNPRVAQIVRDADATCRRELAITIGEIRRATGHEDTPA
                     AIEHMVEVLASLFEGLLVRTIRNPGLDRARVAQRIQIAINDLLDQPN"
     gene            14349..14750
                     /locus_tag="P5537_11335"
     CDS             14349..14750
                     /locus_tag="P5537_11335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004265734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF995 domain-containing protein"
                     /protein_id="HRV78677.1"
                     /translation="MNRLLACAAAALLLGACASTEKELIDKGMKPLDATRAQALLSGN
                     TATGTTASGNGFIIYNAPDGTSRGKSGSSSDAGKWEVTSDGQHCNQWKTWRGGERRCA
                     KLYEVDGEFRYFEGGKYGGRYKIEQGNPYRL"
BASE COUNT         2281 a         5319 c         5152 g         2042 t
ORIGIN      
        1 gcaccgccgg attctggcac cgccggattc tggcaccgcc ggattctggc accgccggat
       61 tcgcgccttc cggcgctcct acacgaaccg ccgcgcccgt aggagcgccg gaaggcgcga
      121 atccggcgct cgggtggaaa cacgccgcgc aatcacacct tcaggtcgac ctggctcagc
      181 gtgccggcac ggccatcctc gcgcagataa acgccgctcg cgcgcatcag accctgggtg
      241 tcgttggcgg cgtccttcag gctgaacggg gtcgccacgc ggccgaggtg gagcgcgccg
      301 acgcccgcct cgcccagcga ccgcacgctg cccttgcccg cagcatctgg ctgccacacg
      361 cgcagctgcg accacgccgc gtccgcctcg tcgatccagc cgttgcggtc gtcgtcgagg
      421 ccggcgagct cggcgaagcc gtctccggtg gccggaccga agagctcgcg accatcgtcg
      481 atgcgcccat tggcgttgcg gtcgaaggcg aggaagccgc tgccgctcat cagtggcagc
      541 ttctccctgc tgccgtcgcc atcgagatcg aagtcgaagc gcacgtccga tagcgccgcc
      601 gcggggccgc cgaagtccag caccagcgga tccttcaggc gctggtcgcc ggcgcgcaca
      661 ctgaccgaca ccgactcggt atggctgcgc gacatctcga agccgagttc gaagcggatc
      721 tcgccgccgt cggcagtgcg caccacgccc gcagcagcga aggacaccgt ctcggtctcg
      781 ctgaagcggc tgctgaaatc gtattcgagc ccgaaaccga cgcgccgtgc gcccccctgg
      841 ccactcgcaa ccgcgttccc gccggtctcg tacccagact cggcggcggt gtcggcgggc
      901 tgcaggtcgc gcatgctgaa gcgccgcacc ggctcgccgg tcaggaactc gatcatgcgg
      961 atcagcatgg caaggcgtgg atcgtcttcg accgcgtcgt cggcaagcgc gtccaccgcc
     1021 gctgtctcgc tctcggtcgc gagcgcgctc tgggccgccg ccgagatctc caccgccggg
     1081 cgcggcacgc ctgcagccgc aggacctgca tcgggcgtgc cgcgccagac ttcgaggcgc
     1141 tcgcgggtct cgagcgactg ggaaaaacgg tgcgaggact gcagctcgac actgaaggcg
     1201 gcgactttca tggggggacc tgcgcggaag acggcaacat cggaggtaac ggccgcaaac
     1261 gccccgggtt gaggcgcagc gcgccgacgg ggcggcccgc gcggacggga aagacgcgag
     1321 caccgatcgg ccctgctcct cgtcgcgctc ctgcatgctc cgggagcggc gtgcccgtct
     1381 cccggccacg gggcgaactg cgctacgatg ggttcatcct tcgcgtgccc ggagtccgcc
     1441 atgagcaaca agcatcgcca taccctggaa gcgatcttcc gtgacccccc ggccggcaac
     1501 ctgcactggc gcgaggtgga gtccctgctg aaccacctcg gcgccgaggt cgagagcggc
     1561 cacggcgcgc gcttccgcgt ggtnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1681 nnntcaggca agcgcgcgag cgagttccgc gatggcctcg tccttgtggc tgccgtccgc
     1741 ctccgcccac tcggggtggg cgcgggcgcg gccgatcgcc tcgggcagcg cgtccttgcg
     1801 ccagcgtgcg ctcaccgggt cggcgttcac cgcggcgccc tcgcgcccgg cgtcgagttc
     1861 gatcggcttt accgcggcat ggccgcgccc gtcgagcgcg accagcagcc tgcgctgacg
     1921 cagcgcgacg atgcgcagga tggcgtcgtc cacggtgagt tcgcggtggc cgcgcagctt
     1981 ggcggcgagg cgctcgccgt aatggccgaa ggtctgccac aggccgccgg cgatggcgcc
     2041 gagcgcggcg gcggcgccca gggtgaggcc gccggtcatc aggtcgatgc cgacccccgc
     2101 ggccgcgccc gcggccgcgc cggtgccgag gcgcacgccc atctggcgca aggtctcggg
     2161 gttgaagagg tcgtcgtccc agcgcccgtc ggcgagcggc aggtcggcca tgcgcgcgtc
     2221 gtcggcgcgg aagcggtaca ggcgcagcag cgcgtccacg caggcctgct cgcggctgcg
     2281 cacgtccgcg cgcaggcgct cgaccgcgac ctgcagcgcg gcgtcgtcat cctctgagtc
     2341 ggccaggcgg tcgcggcgcg cggcgagttc gaccagcagc tcggcgacca ggcggcgggc
     2401 ggcctcgcgc cgtgccgcgg cctcgcgcgc gcgcgcctcg atcaaggctt gcaggcggcc
     2461 gcggtggctg tggatcagcg tggccagggt gtcgaagagc tcgcgctcgc cgtcgagcgg
     2521 cggcgccacg gtgtcgaagc tcaccaccgc gtgcagcccg aggcgggcga gtgcgccgcg
     2581 ccagtcgtcc gcccgcgccg ccggatcggc gatgaagttg agcaccggca gcagcggccg
     2641 agcgcacgcg gcgagcagct caagctcgtc gcggtgcttg ggcagcaccg ggtcgcgcgc
     2701 gtcgaccaca tagagcgcgg cgtcgctcgc cagcatctgg cgcagcacct tcgcctcctg
     2761 ctcgaagcgg cctgcggcct cgtcgcgggc gagaaagcgc gcgacgcgct cggggccgtc
     2821 gacgcgctcg ccggggtcca ccagctcgtc gatgaactcg agcagcgcga tcgcgtcctc
     2881 catgcccggg gtgtcgaaga gctccgccgc cgccacgccg tcggccatca ggcgcaggcc
     2941 ctcgacgtgg cgggtggtgc cggcggagtc ggagacctcg ccgaagccga cgtcgcgcgc
     3001 gagcgtgcgc agcagcgagg tcttgccggt gttggtgtgg cccacgacgg ccacgcgcag
     3061 gatgtcgttc atcggacctc gtccccccgt tccagccaga cccatgcggc ccgcgcatcc
     3121 accagcaccg ccgcctcgcc caggccgatg ccggccaggc cctcgcgcca ctggcgcagc
     3181 cggccggcct gctccgccgc ggcatcgatg ccggccagcc agacgcgggt cgcctgcgcg
     3241 tggtcggcga gctcggcgat gaggccgagg ctgccgcgat ccggggtctg gcgggcgtcg
     3301 accgcgacca ccaggcggac cggcgggtgg gcggcgaaac gcgcgcgcgc tccgcggcgt
     3361 tgctcgcggc tgtcgaggcg gccgccgtcc tcccaggcgg gcaccgccgt ggcgtcgtct
     3421 gcggctgcaa gtgcatgcgg ccacgccagg tcgtcgccga gctcgatcgc cacggccacc
     3481 gcgccgccgt cgccatgggc gaccgcggcg tggcgctgcg ggtgcggcat cgccgccggc
     3541 tcggggtcgc gcacgccgat gcgttcgctg tcgggcatca gcagcgggcg caggcgggcg
     3601 tagccgggac ggccgaggtc gagcacgatc gcagccgtgg cgcgccgcca cagccagaag
     3661 cagagcagcg cgagcgccag ccgcggcagc acgccgtaga tcgtcatcgc ccccaccagc
     3721 cagccagccc aggcgcgccg gccggcctcg tccagcatcg gggcgtcacc gctcgccagc
     3781 accgtggcgg cgtcgggcac cgggaagccg atcatgccgg gcagggcgcc gagcgccgcg
     3841 ctcaatgcga cgaagctgtc ggcgggcagg atggtggtct cccacacgaa gccgtagcgc
     3901 cgcgtggcga gcagcgcgag cacgcccagc gtggcgccgg ccagggcgcc gcaccacagc
     3961 gcgtggttgg ccgcgcccac gccccaggcg gcggtgcggc cgccgccgag caggccgccg
     4021 agcgcgagcg gcaggtcggc agcctcgcgg ctgcggtcga gccagcccgt caccgcaagc
     4081 caggcgcgcc cgagcaggcc accgtggtgc aacgcatcac cctgcgcgcg cccctgcagc
     4141 cccaggctgg cgagccacag cagcaggctc agcagatgca cgccgagcag gccgcccagg
     4201 gtccacacca cattcaccgg ccgcgtgccg tcgccgagcg cgcccgcagc ggcgccgaag
     4261 ccgaaagcga aggcgagcgc gaaggcgagc accagcacca gccgcgcccg cccctgccag
     4321 cgccggatcg cctcgcgcca gccgctggcc gcctcgagca cggcggcgcg gcgcagcacg
     4381 cgtgcttcga gatcgcccgc gaccgcgcgc gcctcggcgt gcgcgcgcgc ctcgtcgagc
     4441 ggcgggtggc gttcttcatg gcggcgcacg agctcggcca gccagcgcag ggacagggaa
     4501 ttcggcggga atgacgtggg cacgcggggt ccggacgata ggtcggcggg aagtcaggaa
     4561 gccgaaggat agcaacctcg ccggcgaagc gcatggactc gaccgcctgc acgaggtccg
     4621 gcacatgccc ggcatggcga atggatgaaa caggtggcga attgatctca atcaacaaag
     4681 atgcagccag aatcgttagc cttgtgtctt ccgctcacca ccggatcgtg ccatgagtac
     4741 cgaactgttc cattggaccg acgagttcag catcggcttg caggagatcg acgaacagca
     4801 caaggagctc gtcgagctgc tcaaccagct tcacgtcgcg atcaaggaac accatggctc
     4861 ggccacctcg cgccagatcc tggacaagct ggccgactac acccgcaccc acttcgcggt
     4921 cgaggagagc ctgatgcggg tgtcgaacta ccccgagttc gccacccaca agcagaacca
     4981 cgaggacctg atcgcccagg tgaaggccct gcaggacaag ctcgactcgg gccaggcgac
     5041 catcaccttc gaactcctgc acttcctcaa ggtctggctc acgcgtcaca tcaacgaggc
     5101 ggacaagcgc ttcggtgcct tcttcctcga ggcgggcggc gccagccgat ggtccgacca
     5161 cgtcgaagat gcgatgaaga agcgcaaatg gtggtggaaa ttctggtgag cagcacgcat
     5221 cgccgccctc atcgtaacgc ccccttgcac cctccgcccg accgccccac acaaccatac
     5281 aaccctccga gaccatgacg atgccgctca ccacccgggc ccgctcggcc ctgcttgccc
     5341 ttgccctccc tgccgccctt ttcgccggcg cggcccacgc cgagacgctg tcctgccctg
     5401 cgctggacaa ggcggtgcag gtcgccgcct gcccgagcga cgcggaactg cagtacacct
     5461 tcatgggctt ctgcggcgac aacgcccgcc tctatggccg cgatgtcttc acctgcgcca
     5521 ccttcgagaa ctacaaggcg gtcaagaaca ccgcgctgtg ggaatcggag aacggcagct
     5581 tcagcggcta cctgaactgc aacctcgaca ccgccaccct gcgcgcctcg cgcgccctga
     5641 agatgagcgt ggagaagaag aacggcctca cccgcctgat ctgcgactat gagaacgacc
     5701 agcgcatggt gatgcgcacg aagggcacct gcaccgtcga agcagccgac tgcagcagcg
     5761 gcgaatgccg cgcgagctgc gagtgagcat cgtctcgagc ccggcactgc gatgacgaac
     5821 accccggctc ccggcgcctc gtcgcctgtc cggcaaaaga ccgcagcctc cgaagcgcgc
     5881 ggcgcacgct tgctggtcgg cctcatcggt ggggccttcc tgctgttgat cgccgccttc
     5941 gtgagcatga tcttcctggc gcaaggcgag gtccgcctca acgcggtggg cccgatcgcc
     6001 gccgcaccgg gcgccgagcg cggtggcgtg gtcttccacg gcacggccaa catctgggag
     6061 gtgcgcgggc gtctgaccca ggacgacgca cgccaggtga gccttgcgat cgatctcgtg
     6121 ggccccaccg cacagccggc gccagccggg ctgcagctca gcctgagcct cgaacgcgcc
     6181 gacggtaccg gcacaccgat cccgctcgac catcgcctgg tacgcccggg cagcctggtg
     6241 gcaaccagcg cgccgctcga gaccggccag tggcggctgc gcctcacctt gcccgaaatc
     6301 gaggcccttc aggagttcag cgtcgagccc tgacgcaccc gcgcgccggc aggcgtgcgg
     6361 ggtcgcgccg ttcagtcccc gacctgcggt acctggccga cgaaactgcc gagaatcgac
     6421 accacctcgt cctgcgccag gtcgcgcacg atgaacacca gccggctgcg gcggtcgtcg
     6481 tagggcggct gcgctggcca ggcgggcagg ctgctccccg gatagacgct gtgctgcacg
     6541 cactgcagca cgcgcggcaa ggggtcgccg gcgacgttga gcaggccctt gatgcgcagg
     6601 atgcggccgc catacacctg cagcagcaac gcgaggccgt cggagaatcc gaaccagtcg
     6661 agcggctcgt cgaagcgcag cacgaagctg gtcacgcctg catcgtggcg cgcgggtgca
     6721 gcgcttgctg cggactcggc ggactcggca tcggccggcg cgccggcgcc gtgcgtcggg
     6781 gcggatttct gtgcgcgcgc acgcgaccac accggcgcgg ccggcgcctg gcgggccgca
     6841 cggaccgcct cctcgcccag ccaggcggcg acgtcgggca gcttgcccgt ggggtcgtag
     6901 aggccacagc cgaacaccgc gtcggcagcg acggcaccgc ccgccacctc cacctggcgc
     6961 gcacccggat tgagccgggc gatgccggcg gcgaccgccg cacgctgccc ggccgaggcc
     7021 aggtcgcact tggtaagcag cagccggtcg gccattgcca cctggcgcac ggcctcgttg
     7081 tgagcgccga gctgatcgag cgcatgggtg acatcgaccg ccgtcaccac accgtcgagc
     7141 cggtagcgct cggacaggaa gggctcggcc atcagggtgt ggatcaccgg cgccgggtcg
     7201 gccaggccgg tggtctcgat cagcacccgg cgcaggccct tgagctcgcg ccgcagcgcg
     7261 cgcatgaaga gccccttgag cgctcgcacg aggtctccct gcacgctgca gcagatgcag
     7321 ccggaatcga gcacgaccag actctcgtcg accttttcca ccagatggtg gtcgacgccg
     7381 accgcgccga actcgttgat cagcaccgcg ctgccgtcca tctgcggctg gcgcagcagg
     7441 tggttgagca aggtggtctt gccggcaccg aggaagccgg tgagcagggt caccgggatg
     7501 cgacggtcgg cgtcggcgga gggcgtggag gcggcgctca tggctgtgca gtgtaactcc
     7561 gcctcacgcc tcacgcctca cgcctcacgc ctcacgcctc actgccagcc gccgccgagg
     7621 gccttgtaga gcgcgacgcg gttggtggcg tcggcgaggc gggtgccgat cagctcgagc
     7681 tcggcaccgt agaggctgcg ctgggcgtcg agcaggttga ggtagctgtc caccccgccc
     7741 ttgtagcgcg cctccgacaa ctcgaagctc ttcttcgccg cggccaccag actgcggcgc
     7801 gcgtcgagct gctcggcgag cgtggcgcgc tcggcgagcg cgtcggcgac ctcgcggaag
     7861 gccgactgga tcgccttctc gtactgcgcg atctggatgt cgcgctgaat ctcggccacg
     7921 tccaggctgg cctgcaggcg cccggcctcg aagatcggca ggcggatctg cggcacgaag
     7981 ctccacgccc ccgagccgcc gtcgaacagg ccgtcgagcg aactgctcgc gctgcccgcc
     8041 gtggcggtga gcgtgatgcg cgggaagaag gccgcacgcg cggcgccgat gctggcgttg
     8101 gcggccatca gcgcgcgctc ggcctgggcg acgtcggggc ggcgggcgag cacctcggag
     8161 ggcacgccgg cgggcagctc ggcgaccgcc gccacacgct cgccgatggc ctgcggctgc
     8221 agctcggccg gcacggcgcc gccggcgacg agcgcgagcg cgttctcgtc ctgcgccacc
     8281 agtgcggcgt agcgtgcggc atcggcacgc gcggtctgca tcagcgtctc ggactggcgc
     8341 agttccaggc cggacaccgc gccgagctcg aagctgcgcc gggtgagctc gaaggacttc
     8401 ttgcgagtct cgaacgtgtc gcgcgccagc gccaggcgct cgcggtcggc ggccaggcgc
     8461 agccaggcgt tggcgacctc ggccaccagg ctgatctgcg cgctgcggcg ggcttcctcg
     8521 gtgccgaggt aagtctgcag cgcctgctcc tccaggctgc gcacgcggcc gaagaagtcg
     8581 agctcgtagc tggcgaagcc gagattggcg ctgtactggc ggctgaccgt cgagtcaccg
     8641 ctcatgctca ggtcgcccgg cacgcgctgc gcgctctgcc cgccgctgac cgcgagcgag
     8701 gggaacaggt cggcgcgctg gatgccgtac tgggcacgtg cgcgctcgat ggcgagcgcg
     8761 gcgacgcgca ggtcgcggtt gttggcgagc gcgagctcga tggtgcgctg caggcggacg
     8821 tcggcgaaat agtcgcgcca ggccagggtg tcgaccgccg gcgccaccgc atcggtcgca
     8881 gccggcgtcg gctgcgcctg cgggaagctg gccggtaccg gcgccacggg gcgctcgaag
     8941 ccggggatca gcgtggtgca ggcaccgagc gtggtggcgg cgagcgccac cacgaggccg
     9001 cgcagcggcc gtctggtttc atgcggggtc atctcaacgt ccctcctggg cagacggcgc
     9061 cacggccgcc tcttggggct tgtccgggaa aatgcgcttg atcacgacgt agaacagcgg
     9121 cacgaagaac aggccgagca gggtcgcgcc gatggtgccg ccgagcacgc cggtgccgat
     9181 cgcgttctgg ctgccggcgc cggcgccggt ggcgatcgcc agcggcagca cgccgaaacc
     9241 gaacgcgagc gaggtcatga tgatcgggcg caggcgcatg cgcaccgcag ccagcgtggc
     9301 ggagatcagg tccttgccct cctccatctg cgccttggcg aactccacga tcaggatcgc
     9361 gttcttcgac gacaggccga tggtggcgag caggccgacc tggaaataca cgtcgttcga
     9421 cagcccgcgc ccgctggcgg cgagcagcgc gccgagcacg ccgagcggca ccaccagcat
     9481 caccgcgaag ggcaccgacc agctctcgta caacgccgcc aggcacagga agaccaccag
     9541 cagcgacagc gcgtacagcg ccggcgcctg cgagcccgag cggcgctcct cgtacgaggt
     9601 gcccgaccag tcgtagccga tgcccggcgg cagcttcgcc atgatctcct cgaccgcctg
     9661 catcgcctcg ccggacgaca gcccgggcgc ggcctggccg agcagctcca tcgacggctg
     9721 gccgttgaag cgctccaggc gcggcgagcc gtaggtccag tgcgcggtgg cgaaggccga
     9781 gaacggcacc atgtcgcccg ccttgttgcg cacgtaccac ttgtcgagat cctccggcgt
     9841 catgcgcgag cccgcgtcgc cctgcaggta caccttcttg atgcggccgc ggtcgaggaa
     9901 gtcgttgatg tagctgccgc cccaggcggt ggacaaggtg tcgttgatgt cggcgaccga
     9961 caggccgagc gccccggcct tggcgtggtc gatgtcgagc ttgagctcgg gcatgtcctc
    10021 ctggccgttg gggcgcacgc cgaccaggcg cttgtcctgc gccgccatgc cgaggaactg
    10081 gttgcgcgcc gccagcaagg cgtcgtggcc gaggccggag cggtcctgca tctgcacggt
    10141 gaagccgccc gaggtgccga gctcgatcac cgcaggcggc acgaaggcga acaccatggc
    10201 ctcgcggatc tgcgcgaacg cgcccatcgc gcgcccggcc acggacttca cgtccttgcc
    10261 cggcgccttg cgctcgtccc agtgcttgag gttcacgaag ccgatgccca tgtgctggcc
    10321 gctgccgccg aagctgaagc cggcgacggt gaagatcgcg cgcacggtgt ccttctcgtt
    10381 ctcgaggaag tggtgctcga ccttcttcag cacctcgagc gtgcgctcct gggtggcgcc
    10441 ggcgggcagc atgacctggt tgaacatcac gccctggtct tcctcgggca ggaaggaggt
    10501 cggcatgcgc acgaagagca ggccgagcac cgcgacgatg gcgaggtaga tggcgaggaa
    10561 gcgcacgctg cgcttgagga tgccgcccac cgccgactcg tagccctggg tgctgcgctc
    10621 gaaccggacg ttgaaccagt ggaagaacct gccgaacagg ccgccttcgc cgtgctcgtg
    10681 ccccttctcc accggcttca ggatgctcgc gcacagggcc ggggtgaaca cgatcgccac
    10741 cagcaccgac agcgccatcg cggacacgat ggtgatcgag aactggcggt agatcacgcc
    10801 ggtggagccg ccgaagaagg ccatcggcac gaacaccgcc gacagcacca ggccgatgcc
    10861 gaccagcgcg ctggtgatct ggtccatcga gcgcttggtg gcctccttgg gcggcaggcc
    10921 ctcctcggtc atcacgcgct cgacgttctc gaccaccacg atggcgtcgt ccaccagcag
    10981 gccgatcgcc agcaccatgc cgaacatggt cagcgtgttg atcgagaagc cgaaggccgc
    11041 catcaggccg aaggtgccga gcagcaccac cgggatcgcc atggtgggga tcagcgtggc
    11101 gcggaagttc tgcaggaaca ggtacatcac caggaagacc agcaccaccg cctcgatcag
    11161 cgtcatcacc accgactcga tcgagatctt tacgaagggc gtggtgtcgt acggcacgac
    11221 gtactcgacg ccttcgggga agtagcgctt catctcgtcg agccgggtgc gcaccgcggt
    11281 cgccgtgtcg agcgcattcg cgcccgaggc gaggcggatg cctacgccgg ctgcgggctg
    11341 gccgttgaag cgcgcgacgg tgccgtagtt ctcggcgccg atctcgacgc gggcgacgtc
    11401 cttcaggcgc acctcgccgc cctgggtgct gctgcgcagc aggatgtcct cgaactcctg
    11461 cacggtctgc aggcggctct gcgcggtgat ggtggcagtg aagccctggc ctggcagcgc
    11521 cggcgtgccg ccgagctggc cggccgagac ctgggtgttc tgcgccatca gcgcggcgcg
    11581 cacgtcaccc ggggtgaggc ggtagttggt gagcctggcg gggtcgatcc acacgcgcat
    11641 cgcgtactgc gcgccgaaga cctgcacctc gcccacgcca tccacgcgcg acagcgggtc
    11701 ctgcaccgag gacaccagga agtcggacag gtcggtgccg gtcatcgagt tgtccgccga
    11761 cacgaagccg accaccatca ggaagttcat cgccgacttg gcgaccgtca ccccctgctg
    11821 ctgcaccgcc tgcggcagca gcggcagcgc ggtctgcatc ttgttctgca cctgcacctg
    11881 ggcgatgtcc gggtcggtgt cggcggagaa ggtgagcgtg gtcgaggcgt tgccgtaggc
    11941 gtcgctggtc gacttcatgt acagcaggcc gtcgaggccg gtgagcttct gctcgatgat
    12001 ctgcgtcacc gagtcttcca ccgccttggc ggaggcaccc gggtacttgg cgttgatgac
    12061 gatcgcgggc ggcgcgatcg acgggtactg ggacaccggc agctgctgga tggacagggc
    12121 gcccgccagc atgatgacga tcgcgatgac ccacgcgaag atgggtcggt cgatgaagaa
    12181 acgggccatg gtcgcctacc tcagctggcc ttggccgcag gcgccgcggc gggcggcgcg
    12241 ccggcgccgg cctcctgggc ctgcaccggg gagcccgggc gggccttctg cagcccctcg
    12301 acgatgatgc gctcgccggc cgccaggccg ccggtcacca cccagtccga accgagcgac
    12361 tgcgccacct tcaccgggcg cgcctcgacc ttgctctcgg catcgaccac catcaccagc
    12421 gcgttgccga gcgggtcgcg gctgagcgcc ttgtgcggca ccaggatggc ctcgctgcgc
    12481 gtgccctgcg gcaggcgcgc gcgcacgtac atgccgggca gcagcacgcc gtcggcattg
    12541 gggaacttcg cgcgcagggt cacgctgccg gtgcccgcat ccacggtgac ctccgagagc
    12601 gccaggcgcc cctcggcggc atattcgctg ccgtcctcca ggaccagctt caccggcacc
    12661 tcgcccctcg cgcccgcctg caggcggccg gcggcgatct cggcgcgcat gcgcagcagg
    12721 tcggcgctcg actgggtgag gtccacatag atcgggtcga gctgctgcac ggtggcgagc
    12781 gcctgcgcct ggttggcggt gacgagcgcg cccggcgtca ccgccgagcg cccgatgcgg
    12841 ccagcgatcg gcgacttgag gcgggtgtag tcgaggtcga tgcgcgcctt gtcgagcgcc
    12901 gccttcgctg cggcgacctc ggcctgggcc tgcttgagcg cggcctgggc gtcgtcgttg
    12961 gcctgcttgc tgacggcctc gatcttcacc agcccggcgt gacgctcggc cttgatgcgc
    13021 gcgacctggg cattggcctc ggcacgggcg agcgcggccc tggcgctgtc gtgggcagcc
    13081 tggtagggag cgtcgtcgat gcggtagagc acctgtccgg ccttgacctc gctgccctcg
    13141 tcgaaggcac gctgggtcag gatgccggtg acctgcgggc gcagctcggc gatcaggtag
    13201 ggcgtagtgc ggccgggcag ctcggtgacc atcggcacgc tgccgctggc gaccgtcatc
    13261 accgtcaccg ccggtgccgg cggcggcccg cctgctcccg gcgcggcgcc ctgttccttg
    13321 ccaccactgc acgcggcaag gagcagggcg cccagcgtca ccatggctgc ggctctgtat
    13381 cgggattggg atcggatctt cattggagcc tcgtgaacgc gaagcgcggc agctccagcg
    13441 agcgaagcgt attcgcagcc agatctcccg cgactagaat gattgttcta gatcgaacgc
    13501 tcattctatg ttatggtttg ttgcaccgca aggcctctca tgacatcgaa gcgcatctgc
    13561 cgttccccgt gagcggattg gcccgcgcca gcaggacagc atgcagactc cggactccag
    13621 ccctcacctc atcgacgcgc cgcgcgctgc tgcacgccgc cagcagatcc tgcacgccgc
    13681 cgcgcagtgc tttcgcgagc acggcttcca cggcgccagc atcgcgctga tctcgaagac
    13741 cgcgggcatg agcccgggtc acatctacca ctatttcgag aacaaggaag cgatcatcgc
    13801 agcgatcgtg gcgcaggatc tcgagagcct gctgacgctg accaccgaac tgcgcgccgc
    13861 ctgcaacgtg cgcgccgcgc tgatcgagcg cgccgccgag ggcgtggccg accagctcga
    13921 ccccgccggc gccgcgctca agctcgagat cgttgccgag gctgcgcgca acccgcgcgt
    13981 ggcgcagatc gtgcgcgatg ccgacgccac ctgccggcgc gagctcgcga tcaccatcgg
    14041 cgagatccgc cgcgccaccg gccacgagga cacgccggcc gcgatcgagc acatggtcga
    14101 ggtgctcgcc agtctcttcg aaggcctgct cgtgcgcacc atccgcaacc ccgggctcga
    14161 ccgcgcgcgc gtcgcgcagc gcatccagat cgccatcaac gatctgctcg accagccgaa
    14221 ttgaatcatt agtgcgaagc attctcgtcg gagttgacga cggcgtgacg aggttctaga
    14281 ccggaagggc ggcattcgtt cgccgtgccg taagcaagaa ccataacgac gacccgacgg
    14341 agactctcat gaacagactg ctcgcctgcg cggcggccgc gctcctgctt ggcgcctgcg
    14401 catccaccga gaaggaactc attgacaagg gcatgaagcc gctcgatgcg accagggccc
    14461 aagccctgct ttccggcaac accgcaaccg gcaccaccgc atccggcaac ggcttcatca
    14521 tctacaacgc cccggatggc acgtcacgcg gcaagagcgg cagcagcagc gacgccggca
    14581 agtgggaagt cacctccgac ggccagcact gcaaccagtg gaagacctgg cgcggcggcg
    14641 agcggcgctg cgccaagctg tacgaggtgg acggcgagtt ccgctacttc gagggtggca
    14701 aatacggcgg ccgctacaag atcgagcagg gcaatcccta ccggctctga gccgctgcag
    14761 caaatcacag aaaggccgga cgcgatcgat cgccgaccga cagcgatcct tcgcgtccac
    14821 cgctactgcc cggatcacta caggtagccg agcctccccg gcagccacag cgcgagctgc
    14881 gggaacacga tcat
//
LOCUS       DAOTIN010000074        14884 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_4828_length_14884_cov_9.281341, whole genome shotgun sequence.
ACCESSION   DAOTIN010000074 DAOTIN010000000
VERSION     DAOTIN010000074.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 14884)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 14884)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14884
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4828_length_14884_cov_9.281341"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1284)
                     /locus_tag="P5537_11340"
     CDS             complement(<1..1284)
                     /locus_tag="P5537_11340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002931725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase-related protein"
                     /protein_id="HRV78678.1"
                     /translation="MKSAEIRDAFLKFFESKGHQIVASSSLVPHEDPTLLFTNAGMNQ
                     FKDVFLGFDKRPYTRATTSQKCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFK
                     RDAISYAWELLTEVFKLPKDKLWVTVYAEDDEAYDIWTREVGVPAERVIRIGDNKGAR
                     YASDNFWMMGDTGPCGPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNNVFMQFNRD
                     EAGVMHPLPKPSVDTGMGLERIAAVLQHVHSNYEIDLFQNLIKAAARETCDADMNSPS
                     LRVLADELSHDFDEDGEQRAETGNAAEGDRPVGRVQQCGQRHEGDELPDLTEDASELH
                     HHRSALRGKPSSDKSQHGREDGGIAGAEQHARDERDTDAGGERHRQLTDRHEHHADGD
                     DGPGTVAVEQYPDRDLHAAIDGELDHGEQREGRGIR"
     gene            complement(1286..1702)
                     /locus_tag="P5537_11345"
     CDS             complement(1286..1702)
                     /locus_tag="P5537_11345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN domain-containing protein"
                     /protein_id="HRV78679.1"
                     /translation="MLRTIADSGPLIALFEPAERNHARVRSFIENYEGALLTTWPVLT
                     EVGHMLGHSVDRQLAFLQWVERGGVEVTTPGAGAVSLIRQLSEKYRDLPMDIADGSLI
                     VLALESGVRDILTLDRDFDVYRLPDRSRFNNVLATT"
     gene            complement(1683..1946)
                     /locus_tag="P5537_11350"
     CDS             complement(1683..1946)
                     /locus_tag="P5537_11350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002931721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HRV78680.1"
                     /translation="MTLSIRLDPELESELARAAAQTGRSKSELVKASLREYLARLAPR
                     KTPYELGKDLFGDPSATAATLDLTSKDRVRSTIVERLRAENDR"
     gene            2069..2620
                     /locus_tag="P5537_11355"
     CDS             2069..2620
                     /locus_tag="P5537_11355"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008817 - corrinoid adenosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="HRV78681.1"
                     /translation="MGNRLSKIYTRTGDAGTTGLGDGKRVSKNSLRIHALGEVDETNA
                     IIGLLLCEELPEDVRVLLTNVQHDLFDLGGEVCIPGMSMITGKQVTHLEEELDRFNEP
                     LEPLKDFILPGGTRAAAYAHHARTVCRRAERALVALALEESVNDAPRQYLNRLSDLLF
                     VLGRVLNRAGGRGDVLWQKRKNA"
     gene            complement(2652..4595)
                     /locus_tag="P5537_11360"
     CDS             complement(2652..4595)
                     /locus_tag="P5537_11360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011766511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV78682.1"
                     /translation="MSDLETHAAAAEPPPAPQPSASADERPVGLGALYRALWEHAAGA
                     RPLLLYAFLLLLASQLFKLAVPWLAGNAINQIQAGGLEGMSEAGRWLGMVFAAIVASW
                     LLHGPGRILERNVALRVRERLAALLVGRLLAAPLAWHERHHSGETTHRMQQSTHALYD
                     FAQSQFIYLQNTVRLVGPIVALWLISPLVGVVALVGYGLIGLLITRFDRVMMRVAVEE
                     NRAERAYSATLVDVLGNVLSVLALRRGEGVARLIGERLAAVFGPLKKSIVLNEAKWCS
                     VDLLASALWCVLVGVYAAEAAGVFGFGAAAGGAAAAAGTIALGKVFMVYEYSQQAGGV
                     ITAIAAHFQSLARQRADYAAAAPLLSAAPAARSADGEDIAASAWRTLGLEGVRFAHGD
                     GRASALELDRLALVRGRRYALVGPSGAGKTTLLRLLAGLDAPTAGVLSIDGESVPVAV
                     AGEPSAAGGLASDAGGVAAMPARLRHLATLIPQQAEMFDGTLAENLLLGADRAPERIE
                     AALHSACADRVVEGLAQGLETRVVEGGANWSGGQRQRLALARGVLAAEGTSLLLLDEP
                     TSSLDPETEAHVYQRLFAHFPDAALVSSVHRLHLLDRFDEVILMRAGRIEAVGRAWEL
                     AQGSALFRELLAAQAVSGEAPGA"
     gene            complement(4609..5724)
                     /gene="dinB"
                     /locus_tag="P5537_11365"
     CDS             complement(4609..5724)
                     /gene="dinB"
                     /locus_tag="P5537_11365"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HRV78683.1"
                     /translation="MRTRKIIHCDCDCFYASVEMRDDPTLRGRPVAVGGRAETRGVIA
                     TCNYEARAFGVHSAMPTARALQLCPQLVLLAPDFERYREASRRILAIYHDYTALVEPL
                     SLDEAYLDVTGVERCRGSASLMAQEIRERIRAEVGITASAGIAPNKFIAKVASDWNKP
                     DGQFVVRPQDVDAFVAALPVKKIFGVGKVTAAKLNRLGVNTCADLRAWSVAELTREFG
                     SFGASLHHLCRGIDERAVQPDRVRKSLSVETTYTPDLHDLAACRAGLLALLEDFHRRF
                     ERARDRPPVHKAFVKVRFSDFSRTTAECVASAPDEAIWLRLLDEAHARKALPVRLLGV
                     GVRFAEEDGSERPAQIPLFDPQLEPDPDPACPAAESH"
     gene            complement(5805..6887)
                     /gene="aroG"
                     /locus_tag="P5537_11370"
     CDS             complement(5805..6887)
                     /gene="aroG"
                     /locus_tag="P5537_11370"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroG"
                     /protein_id="HRV78684.1"
                     /translation="MSASIKLHIDDVRIQEIKELVPPAHVLREFPATPKAAEVAYEAR
                     QAIHRILYGADDRLLVVIGPCSIHDPKAAMEYAHKLKAEAERVKDDLLIVMRVYFEKP
                     RTTVGWKGLINDPGLDNSFRINDGVRLARKLLSEVNEIGLPAGTEFLDMITPQYIADL
                     IAWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLRIAADAIKAAQAPHHFLSVTK
                     AGHSAIVSTRGNEDCHAILRGGKEPNFDADSVDAASRELAAAGVCNKVMVDFSHGNSR
                     KQHRLQIEVAKNVAAQLAAGDDRIMGVMVESHLKEGRQDLVPGKDLEYGKSITDACIG
                     WEDSIDVLDILAEGVRQRRVKRAAEF"
     gene            7090..8025
                     /gene="msrP"
                     /locus_tag="P5537_11375"
     CDS             7090..8025
                     /gene="msrP"
                     /locus_tag="P5537_11375"
                     /EC_number="1.8.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004378077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016667 - oxidoreductase activity, acting
                     on a sulfur group of donors [Evidence IEA];
                     GO_function: GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-methionine-sulfoxide reductase catalytic
                     subunit MsrP"
                     /protein_id="HRV78685.1"
                     /translation="MLIQKPADVLPSEITPRSLFERRRDFLARSGAGLVAGAALWHGL
                     PDSARASTRLQGAPSALSTTEPLTEREAVTTYNNFYEFGTDKADPARNAHKMAVRPWT
                     VNVEGLVGKPRRFDIDELLRLAPLEERIYRLRCVEAWSMVVPWVGFPLAALLKEVEPL
                     GSAKYVEFVTHYDPKIMIRDVIDWPYTEGLRLDEAMHPLTLLALGVYGEVLPNQNGAP
                     LRLVVPWKYGFKSAKSIVTIRLTEKEPATAWNKFAPQEYGFYSNVNPEVRHPRWSQAA
                     ERRIGELRKRPTQMFNGYAEQVASLYQGMDLKKFY"
     gene            8057..8740
                     /locus_tag="P5537_11380"
     CDS             8057..8740
                     /locus_tag="P5537_11380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-methionine-sulfoxide reductase
                     heme-binding subunit MsrQ"
                     /protein_id="HRV78686.1"
                     /translation="MNLSLKAPTAGTIAAVKALVFVLCLLPALDLALGWRADTLGANP
                     IETITRASGEWALRLLLITLAVTPLRRFSGLHWLLRLRRMLGLFAFAYAFGHFTIYLW
                     LDQFFDWNAIALDILDRPFITVGFAAFVLLIPLAATSNGFAIRRLGGRRWQALHRSVY
                     AIAILAVLHFWWLVKADIGRPLLYASILAVLLGLRGWWRELERRRQLSVPPPAKHLEK
                     KVIRLVPRQ"
     gene            complement(9281..10585)
                     /locus_tag="P5537_11385"
     CDS             complement(9281..10585)
                     /locus_tag="P5537_11385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015434366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HRV78687.1"
                     /translation="MSSAPAQLAWEETAEDGALRRCSARWRSESGQAPPRRVVIADDT
                     TKADAAWRLACEGSALLWRGDYHNARQLLQAMARRADGRTRKPGKAARPPATPAEAFH
                     LHRMAQAQRARTLGMLLIPFEAGARIPLRRAPEVAEVLAEAVAGTPDADLAAGPFVMS
                     LRELLGLIGAHEWRRKGVGIPVLGERIHPWYGVYSPIRGEYLDLVARVPLPASTLAFD
                     IGTGTGVIAALLARRGVARVVATDVSPRALGCAQENLARLGLLAEVADPGGALRGANR
                     ANSGASSSAKSGANPDANLGANELPAGRVELLQADLFPPGRAPLVVCNPPWVPAKPSS
                     AIEHAVYDPDSRMLRGFLAGLAEHLEAGGEGWLILSDLAEHLGLRTRAELLGWTEAAG
                     LRVLGREDIRPRHGKAADADDPLHAARAAETTSLWRLGVAKC"
     gene            complement(10588..11178)
                     /gene="mog"
                     /locus_tag="P5537_11390"
     CDS             complement(10588..11178)
                     /gene="mog"
                     /locus_tag="P5537_11390"
                     /EC_number="2.7.7.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin adenylyltransferase"
                     /protein_id="HRV78688.1"
                     /translation="MSEHIRIGLVSISDRASDGTYEDQGIPALKDWLGRALSSPWSAE
                     TRLIPDERALIERTLVELVDVSGCNLVLTTGGTGPAVRDVTPEATLAIGDKEMPGFGE
                     EMRRISLNFVPTAILSRQVAVIRGKCLIINLPGQPKSIRETLEGVRDADGGVRHLGIF
                     AAVPYCIDLVGGPYVETDDAVIKAFRPKHAIRPKQA"
     gene            complement(11175..11762)
                     /gene="yjgA"
                     /locus_tag="P5537_11395"
     CDS             complement(11175..11762)
                     /gene="yjgA"
                     /locus_tag="P5537_11395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis factor YjgA"
                     /protein_id="HRV78689.1"
                     /translation="MRHHHSDPADEDDFPEPPSKSSRKREMQALQDLGEQLVALSPER
                     LKKVPLPESLYEAIRAAQGFKMEARRRQLQYIGKLMRKIDPEPIQAQLDIFAGNSAVE
                     VAKMHRLERLREQLLEDEQVIGTIAETWPEADLQYLRTLRRNALKEREAARPPKSFRE
                     IFRVLRELQEASDAAAEAEAERAADEDATEQGSNP"
     gene            11828..13174
                     /gene="pmbA"
                     /locus_tag="P5537_11400"
     CDS             11828..13174
                     /gene="pmbA"
                     /locus_tag="P5537_11400"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease PmbA"
                     /protein_id="HRV78690.1"
                     /translation="MSSQGFSFSQAHLAEIATDILKYARKHGASSCETDVSEGFGQSV
                     AVRRGEVDTIEYNRDKGVGVTVYLGQQRGYASTSDFSKKALKSTVDAALSIARFTAPD
                     PCAGLADAALMAKAKDMPELDLFHPWNIDVAEAIELARRCENAAFAVSPKISNSEGAN
                     TSIQQSHFVSANSHGFLGGYATTRHGLSCSVIAGEGDGMQREYWYDSRRDPAELMAAE
                     DVGRLAGERALARLGAKKIRTCEVPVLFEAQLAVALIGNFVQAVSGGSLYRKSSFLLD
                     SLGHQVFSPVVSIAERPHLQKAFGSSPFDGDGVATRDREVVTDGVLNGYFLSTYSARK
                     LGMQTTANAGGSHNLIVKPGDQDLTGLIRQMDRGLLVTELLGHGVNYVTGDYSRGAAG
                     FWIEKGRIKHAVEEITIAGNLRDMFRSIVAVGNDALPRGAKLCGSVLIERMKVAGR"
     gene            13294..14400
                     /locus_tag="P5537_11405"
     CDS             13294..14400
                     /locus_tag="P5537_11405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HRV78691.1"
                     /translation="MERRSFLKKASVGLAAGAAAGVASTAAVAAPAVQTGLPEIKWRM
                     TSSFPKSIDTLYGSSELLANRLREITGGKFDIRIFPAGEIVPGLQALDAVQQGTVEMC
                     HSCSYYYVGKDKTFAFGTAVPFGMNARQMDAWIIGGGGQELLDEFYGNYNVYSFLGGN
                     TGVQMGGWYRKQINTLDDIKGLKIRIAGIAGEIMSRMGAIPQQIAGSDIYPSLEKGTI
                     DAAEWVAPYDDEKLGFYKVAPHYYSPGWWEPGPVVHFYVNKAEWDKLPKEYQAAFRAA
                     SREAHIQMTAMYDHKNPQALARLLAQGVKLQNFSNDIMKKAFEVSRELYAEEAAKNPA
                     WAKIYTEFEKYRKSQNAWFSVAEAGFDRFMQSVR"
     gene            complement(14463..>14884)
                     /locus_tag="P5537_11410"
     CDS             complement(14463..>14884)
                     /locus_tag="P5537_11410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HRV78692.1"
                     /translation="VLAFFLDYFELAFIIVPLLAPVAEKLGIDLIWFGVLLAVNMQTS
                     FLHPPFGFALFFLRSVASEKVKTASIYWGAVPFVIIQLIMVGLIIAFPGLVSYGDAGA
                     KPAQQQELDLEQLLQGGGGAAPAGDSSSDLMRQLQGN"
BASE COUNT         2300 a         5124 c         5153 g         2307 t
ORIGIN      
        1 gcggatgcct cgaccctctc gctgttcgcc gtgatccagc tcgccgtcta tggcggcatg
       61 cagatcccga tcggggtact gctcgaccgc tacggtgccc ggcccatcat caccatcggc
      121 atggtgctca tggcggtcgg tcagctgacg atggcgctct cccccagcat cggtatcgcg
      181 ctcgtcgcgc gcgtgctgct cggcgccggc gatgccgccg tcttccctgc cgtgctgcga
      241 cttgtcgcta cttggtttcc cacgcagcgc gctccggtga tggtgcagtt cactggcatc
      301 ctcggtcaga tcgggcagct catcgccctc gtgccgctgg ccgcactgct gcacgcgacc
      361 aactggacga tcaccttcgg cagcattgcc ggtctcggca cgctgttcgc catcctcgtc
      421 gaaatcatgg gagagttcgt cggccagcac gcgcagcgac ggactattca tgtcggcgtc
      481 gcacgtttca cgcgcggcgg ccttgatcag gttctgaaag aggtcgatct cgtagttgct
      541 gtgtacatgc tgcagcacgg cagcgatccg ctcgagcccc atgccggtat cgaccgacgg
      601 cttgggtagc ggatgcatga cgcccgcctc gtcgcggttg aactgcatga acacgttgtt
      661 ccagatctcg atgtagcggt cgccgtcttc ctcgggcgat cccggggggc cgccccagat
      721 gtggtcgccg tggtcgtaga agatctcggt gcacggaccg caggggccgg tgtcgcccat
      781 catccagaag ttgtcggacg cataacgcgc gcccttgttg tcgccaatgc ggatcacccg
      841 ctccgccggc acgccgactt ccctggtcca gatgtcgtag gcctcgtcgt cctcggcgta
      901 caccgtgacc cagagcttgt ccttgggcag cttgaagacc tcggtgagca gctcccaggc
      961 gtacgaaatc gcgtcgcgct tgaagtagtc gccgaagctg aagttgccca gcatctcgaa
     1021 gaaggtgtgg tggcgcgcgg tgtagccgac gttctcgagg tcgttgtgct tgccgccggc
     1081 gcgcacgcac ttctgcgagg tggtggcgcg ggtgtagggg cgcttgtcga agccgaggaa
     1141 cacgtccttg aactggttca tgccggcgtt ggtgaacagc agcgtcgggt cctcgtgcgg
     1201 cacgagcgag ctggaggcca cgatctggtg gcccttggat tcgaagaact tgaggaaggc
     1261 gtcgcggatt tcagcggatt tcatgtcagg tcgtggccag gacgttgttg aatcgggagc
     1321 gatcggggag acgataaacg tcgaagtccc ggtcgagtgt caggatgtcg cgcacaccac
     1381 tttcgagcgc gagcacgatc agcgacccgt cggcgatatc catcggcagg tcgcggtatt
     1441 tttcggagag ctggcggatc agcgagacgg cgcccgcgcc gggcgtcgtc acctccacgc
     1501 caccacgctc cacccattgc aggaaggcga gctggcgatc gaccgaatga ccgagcatgt
     1561 ggccgacttc ggtcagcacc ggccaggtgg tcagaagcgc cccctcgtag ttctcgatga
     1621 agctgcgcac acgcgcgtgg ttgcgctcgg cgggctcgaa cagcgcgatc agcggcccgg
     1681 agtcagcgat cgttctcagc acgcagccgc tccacgatgg tgctgcggac gcggtccttg
     1741 ctggtgagat cgagcgtcgc cgccgtggcg gacggatcgc cgaacaggtc cttgccgagc
     1801 tcgtagggcg tcttgcgcgg cgcaagccgg gcgagatatt cgcgcaggct ggccttgacc
     1861 agctcgctct tgctgcggcc agtctgcgcg gcggcgcgcg cgagttcgga ctcgagctcg
     1921 ggatcgaggc ggatcgacag ggtcatgggg ccggcttcct gtattacaca acgtattgca
     1981 tcgtatgacg cgctgcgatc gaagtcaatt tcagccgctc gcgcctataa ttatgcgtta
     2041 cgacaaccac cccggacacg aggacatcat gggtaaccgc ctctccaaga tctacacccg
     2101 caccggcgac gccggcacca ccggcctcgg cgacggcaag cgcgtctcca agaacagcct
     2161 gcgcatccac gccctgggcg aggtcgacga gaccaacgcc atcatcggcc tgctgctgtg
     2221 cgaggagctg cccgaggacg tgcgcgtgct gctgaccaac gtgcagcacg acctcttcga
     2281 cctcggcggt gaggtgtgca tcccgggcat gagcatgatc accggcaagc aggtcacgca
     2341 tctggaagaa gagctcgacc gcttcaacga gccgctcgag ccgctcaagg acttcatcct
     2401 gcccggcggc acccgcgccg ccgcctacgc ccaccacgcc cgcaccgtct gccgtcgcgc
     2461 cgagcgcgcg ctggtggcac tggcgctgga agagtcggtg aacgacgccc cgcgccagta
     2521 cctcaaccgc ctctccgacc tcctcttcgt gctcggccgc gtgctcaacc gcgccggcgg
     2581 ccgcggcgac gtgctgtggc agaagcgcaa gaatgcgtga ggggtgaggg tgaggggtca
     2641 ggcgtaaggg gtcaggcgcc gggcgcctcg ccgctcaccg cctgggcggc gaggagctcg
     2701 cggaagagcg cggagccctg cgccagctcc caggcgcggc cgaccgcctc gatgcggccg
     2761 gcgcgcatca ggatgacctc gtcgaagcgg tcgagcaggt gcagccggtg caccgaggac
     2821 accagcgccg catccgggaa gtgcgcgaac aggcgctggt agacgtgcgc ctcggtctcc
     2881 gggtccaggc tgctggtggg ctcgtcgagc agcaacaggc tcgtgccctc ggcggcgagc
     2941 acgccgcgcg cgagcgccag gcgctggcgc tgcccgccgg accagttggc gccgccctcc
     3001 accacgcgcg tctccaggcc ctgcgccagg ccctcgacca cgcggtcggc gcaggccgaa
     3061 tgcagcgcgg cctcgatgcg ctcgggcgcg cgatcggcgc cgagcagcag gttctcggcc
     3121 agcgtgccgt cgaacatctc ggcctgctgc gggatcaggg tggcgagatg gcgcaggcgc
     3181 gcgggcatcg cggccacgcc cccggcgtcg ctcgccaagc cgccagcggc ggacggctcg
     3241 ccggcgaccg ccacgggcac ggactcgcca tcgatcgaca ggacgcccgc cgtgggcgcg
     3301 tccagcccgg cgagcaggcg cagcagggtg gtcttgcccg cgccgctcgg gccgaccagg
     3361 gcgtagcgcc ggccgcgcac gagcgccagg cggtcgagct cgagcgcgct ggcacggcca
     3421 tcgccatggg cgaagcgcac cccctccagg cccagcgtgc gccaggccga ggcggcgatg
     3481 tcctcgccgt cggcggaacg cgccgccggc gcggcactga gcagcggcgc ggcggcggcg
     3541 tagtcggcgc gctggcgggc gagcgactga aagtgggccg cgatcgcggt gatcaccccg
     3601 ccggcctgct gcgagtactc gtacaccatg aagaccttgc cgagcgcgat cgtgccggcc
     3661 gccgccgcgg ccccgcccgc ggcggcgccg aagccgaaca cgcccgcggc ctccgccgca
     3721 tacacgccga ccagcacgca ccacagcgcg ctcgcgagca ggtccaccga gcaccacttg
     3781 gcctcgttga gcacgatgct cttcttcagc ggcccgaaca ccgccgccag gcgctcgccg
     3841 atcagccgcg ccacgccctc gccacgccgc agcgcgagca ccgacagcac gttgccgagc
     3901 acatcgacca gagtggcgga ataggcgcgc tcggcgcggt tctcctccac cgccacgcgc
     3961 atcatcacgc ggtcgaagcg ggtgatgagc aggccgatga gcccgtagcc gaccagcgcc
     4021 accacgccca ccagcggcga gatcagccac agcgcgacga tcggccccac caggcgcacg
     4081 gtgttctgca ggtagatgaa ctggctctgc gcgaagtcgt agagcgcatg cgtgctctgc
     4141 tgcatgcggt gggtggtctc gcccgagtgg tggcgctcgt gccaggccag cggcgcggcg
     4201 agcaggcgac ccacgagcag ggcggcgagg cgctcgcgca ccctgagcgc gacgttgcgc
     4261 tcgaggatgc gccccggccc gtgcagcagc cagctcgcga cgatggccgc gaagaccatg
     4321 ccgagccagc gcccggcctc gctcatgccc tccagcccgc cggcctggat ctggttgatc
     4381 gcgttgccgg ccagccaggg cacggcgagc ttgaacagct gggacgcgag cagcagcagg
     4441 aaggcgtaga gcagcagcgg gcgcgcgccc gcggcgtgct cccacaacgc acggtagagc
     4501 gcgccgaggc ccaccgggcg ctcgtcggcg gacgcggacg gctgcggcgc gggcggcggc
     4561 tcggccgcgg cggcgtgggt ttcgaggtcg gacatcgcgg gctccgcgtc agtgggattc
     4621 cgccgcgggg cacgcgggat cggggtcggg ttccagttga ggatcgaaga gcgggatctg
     4681 cgccggccgc tcgcttccgt cctcctcggc gaagcgcacg ccgacgccga gcaggcgcac
     4741 cggcagcgcc ttgcgcgcgt gcgcctcgtc gagcaggcgc agccagatgg cctcgtcggg
     4801 cgcgctggcg acgcactcgg cggtggtgcg gctgaaatcg gagaagcgca ccttgacgaa
     4861 ggccttgtgc accggcgggc ggtcgcgcgc gcgctcgaag cgacggtgga agtcctccag
     4921 cagcgcgagc aagccggcgc ggcaggcggc gaggtcgtgc aggtcggggg tgtaggtggt
     4981 ctccacggac agcgacttgc gcacgcggtc gggctgcacc gcgcgctcgt cgatgccgcg
     5041 gcacaggtgg tgcaggctgg cgccgaagct gccgaactcg cgggtgagct cggccacgct
     5101 ccaggcgcgc aggtcggcgc aggtgttcac accgagacgg ttgagcttcg ccgcggtgac
     5161 cttgccgaca ccgaagatct tcttcaccgg cagcgcggcg acgaaggcgt cgacgtcctg
     5221 cgggcgcacc acgaactggc cgtcgggctt gttccagtcg ctcgccacct tggcgatgaa
     5281 cttgttgggc gcgatgccgg ccgaggcggt gatgccgacc tcggcgcgga tgcgttcgcg
     5341 gatttcctgc gccatcagcg aggccgagcc gcggcagcgc tcgaccccgg tcacgtcgag
     5401 gtaggcctcg tcgagcgaca gcggctccac cagcgcggtg tagtcgtggt agatcgccag
     5461 aatccggcgc gaggcctcgc ggtagcgctc gaagtcgggc gccagcagga cgagctgcgg
     5521 gcacagctgc agcgcgcgcg cggtgggcat cgccgaatgc acgccgaagg cgcgcgcctc
     5581 gtagttgcag gtggcgatca ccccgcgcgt ctcggcgcgc ccgcccaccg cgaccggcct
     5641 gccgcgcagc gtcgggtcgt cgcgcatctc gaccgacgcg tagaagcagt cgcaatcgca
     5701 gtggatgatc ttacgcgtgc gcatgcgcgc gggaggcgtc aggggtgagg cgtgaggggc
     5761 gaaggggcct gccgggggca ggccgggtgg agtgccgtcc gcgctcagaa ctcggcggcg
     5821 cgcttgacgc ggcgctggcg cacgccctcg gcgaggatgt cgagcacgtc gatgctgtct
     5881 tcccagccga tgcaggcgtc ggtgatgctc ttgccgtact cgaggtcctt gcccgggacg
     5941 agatcctggc ggccttcctt gaggtgggac tcgaccatca cgcccatgat gcggtcgtcg
     6001 cccgcggcga gctgggcggc cacgttcttc gccacctcga tctgcaggcg gtgctgcttg
     6061 cggctgttgc cgtgggagaa atcgaccatg accttgttgc acaccccggc cgcggcgagc
     6121 tcgcggctgg cggcatcgac gctgtcggcg tcgaagttgg gctccttgcc accgcgcagg
     6181 atggcgtggc agtcctcgtt gccgcgggtc gaaacgatcg ccgagtggcc ggccttggtc
     6241 accgacagga agtggtgcgg cgcctgcgcg gccttgatcg cgtcggcggc gatgcgcagg
     6301 ttgccgtcgg taccgttctt gaagcccacc gggcaggaca ggcccgaggc gagctcgcgg
     6361 tgtacctggc tctcggtggt gcgcgcaccg atcgcgcccc aggcgatcag gtcggcgatg
     6421 tactgcgggg tgatcatgtc gaggaactcg gtgcctgccg gcaggccgat ctcgttgacc
     6481 tccgacagca gcttgcgcgc caggcgcacg ccatcgttga tgcggaagct gttgtccagc
     6541 ccggggtcgt tgatcagtcc cttccagccc acggtggtgc gcggcttctc gaaatagacg
     6601 cgcatcacga tcagcaggtc gtccttgacg cgctcggcct cggccttgag cttgtgcgcg
     6661 tactccatcg ccgccttggg gtcgtggatc gagcacgggc cgatcaccac cagcaggcgg
     6721 tcgtcggcgc cgtacaggat gcggtggatc gcctggcgcg cctcgtaggc gacctcggcc
     6781 gccttgggcg tggccggaaa ctcgcgcagc acgtgcgcgg gcggcacgag ctccttgatc
     6841 tcctggatgc ggacgtcgtc gatatgcagt ttgatggagg cggacatgcg agactctttg
     6901 tcggatcttt gctggggtgc ccgattctag cggaaagccg cccatggctg gacgcaatgc
     6961 ggactataag cccgatggga tgaaccgatc ggcgccgaac gcgtctgttc gtacactgcc
     7021 gcccgcgctt cgtcgcggcc ggcgcctgcc tgcaccctcg aatcccccgt tccaaacgag
     7081 cccgcaatca tgttgatcca gaagcccgcc gacgtccttc cctccgagat caccccgcgc
     7141 agcctcttcg agcgccgccg cgacttcctc gcccgcagcg gcgcgggact ggtcgcgggt
     7201 gcggcgctct ggcacggcct gcccgacagc gcgcgtgcct ccacccgcct gcagggcgcg
     7261 ccctcggcgc tgagcaccac cgagccgctc accgaacgcg aggccgtcac cacctacaac
     7321 aacttctacg agttcggcac cgacaaggcc gacccggcac gcaacgccca caagatggcg
     7381 gtgcgcccat ggacggtgaa tgtggagggc ctggtcggca agccgcgtcg cttcgacatc
     7441 gacgagctgc tgcgcctggc gccgctggag gagcgcatct accgcctgcg ctgcgtggag
     7501 gcctggtcga tggtggtgcc ctgggtgggc tttccgctcg ccgcgctgct gaaggaggtc
     7561 gagcccctgg gcagcgcgaa gtacgtcgag ttcgtcaccc actacgaccc gaagatcatg
     7621 atccgcgacg tgatcgactg gccctacacc gagggcctgc gcctggacga ggccatgcac
     7681 ccgctgaccc tcctggcgtt gggcgtgtat ggcgaggtgc tgcccaacca gaacggcgcg
     7741 ccgctgcgcc tggtggtgcc atggaaatac ggcttcaaga gcgccaagtc gatcgtcacc
     7801 atccgcctca ccgaaaagga gcccgcgacc gcgtggaaca agttcgcgcc gcaggagtat
     7861 ggtttctact ccaacgtgaa ccccgaggtg cggcacccgc gctggagcca ggccgccgag
     7921 cgccgcatcg gcgaattgcg caagcgtccg acgcagatgt tcaacggcta tgcggagcag
     7981 gtcgcgagcc tctaccaggg catggacctg aagaagttct attgagccgc gcgctcctcc
     8041 tcgcccgatc aagacaatga atctctccct gaaagcgccc accgcgggca ccatcgccgc
     8101 cgtcaaggcg ctcgtgttcg tcctctgcct gctgcccgcg ctggatctcg cgctcggctg
     8161 gcgggccgac acgctcggtg ccaacccgat cgagacgatc acccgcgcca gcggcgagtg
     8221 ggcgctgcgc ctgttgctga tcaccctggc ggtgacgccg ctgcgccgct tcagcggtct
     8281 gcactggctg ctgcgcctgc gccgcatgct cgggctgttc gcgttcgcct atgcgttcgg
     8341 gcatttcacc atctacctgt ggctggacca gttcttcgac tggaacgcga tcgcgctcga
     8401 catcctcgac cggcccttca tcaccgtcgg tttcgccgcc ttcgtgctgc tgatcccgct
     8461 cgccgccacc tcgaacggct tcgccatccg ccgcctcggc gggcgcaggt ggcaagcgct
     8521 gcaccgctcg gtgtatgcga tcgcgatcct cgcggtgctg catttctggt ggctggtgaa
     8581 ggcggatatc ggcaggccgc tgctgtacgc gagcatcctc gccgtgctgc tcggcttgcg
     8641 cggctggtgg cgcgagctcg agcgccgccg ccagctctcg gtgccgccgc cggcgaagca
     8701 cctggaaaag aaggtgatcc ggctggtgcc acggcagtag gctctgtaag ctcgcacgca
     8761 cgtcgttcga tcgaccgctc attcgcggct gccgccgctc ctacaaaggg acggaaccgc
     8821 ggtgctctct gtaggagcgc cggcaggcgc gaaggcggcg atgcaagctc gcacgcgcgt
     8881 cgttcgatcg accgctcatt cgcggctgcc gccgctccta caaagggacg gaaccgcggt
     8941 gctctctgta ggagcgccgg caggcgcgaa ggcggcgatg caagctcgca cgcgcgtcgt
     9001 tcgatcgacc gctcattcgc ggctgccgcc gctcctgcaa agggacggaa ccgcggtgct
     9061 ctctgtagga gcgccggcag gcgcgaaggc ggcgatgcaa gctcgcacgc gcgtcgttcg
     9121 atcgaccgct cattcgcggc tgccgccgct cctgcaaagg gacggaaccg cggtactctc
     9181 tgtaggagcg ccggcaggcg cgaaccagcc ctcgggaata ccccgaacgc actcggcccc
     9241 tatcgaaaca gctcgacggc gagccgagcg cgtccgcagc tcagcacttc gcgacgccca
     9301 ggcgccacag cgaggtcgtc tccgcggccc gcgccgcatg cagcgggtcg tccgcatcgg
     9361 ccgccttgcc gtggcgtggg cggatgtcct cgcgaccgag cacgcgcagg cccgcggcct
     9421 cggtccagcc gagcagctcg gcgcgcgtgc gcaggccgag gtgttcggcg aggtcggaaa
     9481 gaatcagcca gccctcgccg cccgcctcca ggtgttccgc caggccggcc aggaagccgc
     9541 gcagcatgcg gctgtcgggg tcatagaccg cgtgctcgat cgcggagctc ggcttggcgg
     9601 gcacccaggg cgggttgcac accaccagcg gcgcgcggcc gggcgggaag aggtcggcct
     9661 gaagcaactc gacacggccg gcgggaagct cattggcacc caggttcgca tccgggttcg
     9721 cgcccgactt cgcacttgag ctggcgcccg agttcgcgcg attggctccg cgaagggcgc
     9781 cccccgggtc cgcgacctcg gccagcagcc caaggcgcgc gaggttctcc tgcgcgcaac
     9841 ccagcgcacg cggcgacacg tcggtggcca ccacgcgcgc caccccgcgg cgtgcgagca
     9901 gcgcggcgat gacgccggtg ccggtgccga tgtcgaaggc cagcgtgctc gcgggcagcg
     9961 gcacgcgcgc gacgaggtcg agatactcgc cgcggatcgg cgaatagacg ccgtaccacg
    10021 gatggatgcg ctcgccgagc accgggatgc cgacgccctt gcgccgccac tcgtgcgcgc
    10081 cgatgaggcc gagcagctcg cgcagcgaca tcacgaaggg ccccgcagcg agatcggcat
    10141 ccggcgtccc ggcgaccgcc tcggcaagga cctctgccac ctcgggcgcg cgccgcagcg
    10201 ggatgcgcgc gccggcctcg aaggggatca gcagcatccc cagcgtacgc gcgcgctgcg
    10261 cctgcgccat gcggtggagg tggaaggctt cggcgggggt agcgggcggc ctggccgcct
    10321 tgcccggctt gcgcgtgcgg ccgtcggcgc gccgcgccat ggcctgcagc agctggcggg
    10381 cgttgtggta gtcaccgcgc cacagcagcg cgctgccctc gcaggccagc cgccaggcgg
    10441 cgtcggcctt ggtggtgtcg tcggcgatca ccacccggcg cggtggcgcc tggccgctct
    10501 ccgagcgcca gcgcgcgctg catcgacgga gcgccccgtc ctccgcggtc tcttcccagg
    10561 cgagctgggc gggcgcgctc gacatgctca cgcctgcttc ggccggatcg cgtgcttggg
    10621 tcggaaggcc ttgatcaccg catcgtcggt ctcgacgtag gggccgccga cgaggtcgat
    10681 gcagtacggg accgcggcga agatgccgag gtggcgcacg ccgccatcgg cgtcgcgcac
    10741 gccttcgagg gtctcgcgga tcgacttggg ttgaccgggc aggttgatga tcaggcactt
    10801 gccgcggatc accgcgacct ggcgcgacag gatggccgtg ggcacgaagt tgaggctgat
    10861 gcggcgcatc tcctcgccga agcccggcat ctccttgtcg ccgatcgcga gcgtggcctc
    10921 gggggtcacg tcgcgcaccg ccgggccggt gccgccggtg gtgagcacca ggttgcaacc
    10981 ggaaacgtcg acgagctcga ccagggtgcg ctcgatcagc gcgcgctcgt cggggatcag
    11041 ccgggtctcg gcactccatg gggagctcag cgccctgccc agccagtcct tcagcgcagg
    11101 gatgccctgg tcttcgtagg tgccgtcgga ggcacggtcg ctgatcgaca ccaggccgat
    11161 gcggatgtgt tcactcatgg gttcgatccc tgttcggttg cgtcctcatc ggcagcgcgc
    11221 tccgcctcag cctcggcagc ggcgtcgctg gcttcctgca actcgcgcag cacacggaag
    11281 atctcgcgga aggacttcgg cggcctggcg gcctcgcgtt ccttcaaggc gttgcggcgc
    11341 agggtgcgca ggtattgcag gtcggcctcg ggccaggtct cggcgatggt gccgatgacc
    11401 tgctcgtcct cgagcaactg ctcgcgcagg cgctcgaggc ggtgcatctt cgccacctcg
    11461 acggccgagt tgccggcgaa gatgtcgagc tgggcctgga tgggctcggg gtcgatcttg
    11521 cgcatcagct tgccgatgta ctgcagctgg cggcggcgcg cttccatctt gaagccctgg
    11581 gcggcacgga tggcctcgta caggctctcg ggcagcggca ccttcttgag gcgctcgggc
    11641 gagagtgcga cgagctgctc gccgaggtcc tgcagcgcct gcatctcgcg cttgcggctg
    11701 ctcttgctcg gcggctcggg aaagtcgtcc tcgtcagcgg ggtcggaatg gtggtggcgc
    11761 attgcttgca tggggggctg gctcgatcgg ggtaagatta tagcctttgc acgcacccgg
    11821 cccgcccatg tccagccaag gcttctcctt ctcgcaggcg catctcgccg agatcgccac
    11881 cgacatcctc aaatacgccc gcaagcacgg cgcctcgtcg tgcgagaccg atgtctccga
    11941 gggcttcggc cagtcggtgg cggtgcgccg cggcgaggtc gacaccatcg agtacaaccg
    12001 cgacaagggc gtcggtgtca ccgtctacct cggccagcag cgcggctatg cgagcacctc
    12061 cgacttctcg aagaaggcgc tcaagtcgac cgtggatgcg gcgctgtcga tcgcgcgctt
    12121 caccgcaccc gacccgtgcg ccggactcgc ggacgcggca ctgatggcga aggcgaagga
    12181 catgcccgag ctcgacctct tccatccgtg gaacatcgac gtcgccgagg cgatcgagct
    12241 cgcgcgccgc tgcgagaacg cggccttcgc ggtcagcccg aagatcagca actcagaggg
    12301 cgccaacact tcgatccagc agtcgcactt cgtgtcggcc aacagccacg gcttcctggg
    12361 cggctacgcc accacgcgcc acggcctgtc gtgctcggtg atcgcgggcg aaggcgacgg
    12421 catgcagcgc gagtactggt acgactcgcg acgcgatccc gccgagctga tggcggccga
    12481 ggacgtcggc cggctggccg gcgagcgtgc gctggcgcgc ctgggcgcga agaagatccg
    12541 cacctgcgag gtgccggtgc tgttcgaggc gcagctcgcg gtcgcgctga tcggcaactt
    12601 cgtgcaggcg gtgagcggcg gctcgctcta tcgcaagtcg agcttcctgc tcgacagcct
    12661 cggtcatcag gtgttctcgc cggtggtgag catcgccgag cgccctcacc tgcagaaggc
    12721 cttcggctcc agccccttcg acggcgacgg cgtcgccacc cgcgaccgcg aggtcgtcac
    12781 cgacggcgtg ctgaacggct acttcctgtc cacctactcg gcgcgcaagc tcggcatgca
    12841 gaccactgcc aacgccggcg gctcgcacaa cctgatcgtg aagccgggcg accaggacct
    12901 caccgggctg atccggcaga tggaccgtgg gctgctcgtc accgagctgc tcggccatgg
    12961 cgtgaattac gtcacgggcg attactcgcg cggtgcggca ggcttctgga tagagaaagg
    13021 ccgcatcaag cacgccgtcg aggagatcac catcgccggc aacctgcgcg acatgttccg
    13081 cagcatcgtc gcggtcggca acgacgccct gccgcgcggt gcaaagttgt gcggctcggt
    13141 gctgatcgag cgcatgaagg tggccgggcg ctgagccacc cgagaggcct cgctgcgaca
    13201 acgccagccg tttctgcccc gatcaccgat cgggatctat aatcttttgc cgaattcgct
    13261 cgaatccccc ccaaaaaaac gcaaggagaa atcgtggaac gtcgttcatt cctgaagaag
    13321 gccagtgtcg gcctggccgc cggtgccgcc gcaggcgtcg cctccaccgc agccgtcgcc
    13381 gctcccgccg tccagacggg gctgcccgag atcaagtggc gcatgacctc gagcttcccc
    13441 aagagcatcg acacgctcta cggcagttcc gagctcctcg ccaaccgcct gcgcgagatc
    13501 accggcggca agttcgacat ccgcatcttc ccggccggcg agatcgtccc cggcctgcag
    13561 gcgctcgacg ccgtgcagca gggcacggtc gagatgtgcc actcgtgctc gtactactac
    13621 gtcggcaagg acaagacctt cgccttcggc accgccgtgc ccttcggcat gaacgcccgc
    13681 cagatggacg cctggatcat cggcggcggc ggtcaggagt tgctcgacga gttctacggc
    13741 aactacaacg tgtactcctt cctcggcggc aacaccggcg tgcagatggg cggctggtat
    13801 cgcaagcaga tcaacaccct ggatgacatc aagggcctga agatccgcat cgccggcatc
    13861 gccggcgaga tcatgtcgcg catgggcgcg atcccgcagc agatcgccgg ttcggacatc
    13921 tacccctcgc tcgagaaggg cacgatcgac gccgccgaat gggtcgcccc ctacgacgac
    13981 gagaagctcg gcttctacaa ggtggcaccg cattactact cgccgggctg gtgggagccg
    14041 ggtccggtgg ttcacttcta tgtgaacaag gccgagtggg acaagctgcc caaggaatac
    14101 caggcagcgt tccgcgccgc ctcgcgcgag gcacacatcc agatgaccgc gatgtacgac
    14161 cacaagaacc cgcaggcgct cgcacgcctg ctcgcgcagg gcgtgaagct gcagaacttc
    14221 tccaacgaca tcatgaagaa ggcctttgag gtgtcgcgcg agctgtatgc cgaggaagcc
    14281 gcgaagaacc cggcctgggc gaagatctac accgagttcg agaagtaccg caagtcgcag
    14341 aacgcgtggt tcagcgtcgc cgaggcgggc ttcgaccgct tcatgcagtc ggtgcgctga
    14401 gggcgtcagg cgtcaggcgt gaaaaagccg ggcattgccc ggctttttcg tggtgcgtgc
    14461 gctcagttgc cctggagctg acgcatgagg tcggagctcg agtcgcccgc gggcgcggcc
    14521 ccgccgccgc cctgcagcaa ctgctcgagg tcgagctcct gctgctgcgc cggcttggca
    14581 cccgcgtcgc cgtaggacac cagccccggg aaggcgatga tgaggcccac catgatcagc
    14641 tggatgatca cgaagggcac cgcaccccag tagatcgacg ccgtcttgac cttctcggag
    14701 gccaccgagc gcaggaagaa cagcgcgaag ccgaagggcg ggtgcaggaa ggaggtctgc
    14761 atgttcaccg ccagcagcac gccgaaccag atcaggtcga tgccgagctt ctcggccacc
    14821 ggcgcgagca ggggcacgat gatgaaggcg agttcgaagt agtcgaggaa gaaggcgagc
    14881 acga
//
LOCUS       DAOTIN010000075        14743 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_4889_length_14743_cov_8.968273, whole genome shotgun sequence.
ACCESSION   DAOTIN010000075 DAOTIN010000000
VERSION     DAOTIN010000075.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 14743)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 14743)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14743
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4889_length_14743_cov_8.968273"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..2305
                     /locus_tag="P5537_11415"
     CDS             <1..2305
                     /locus_tag="P5537_11415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="crotonase/enoyl-CoA hydratase family protein"
                     /protein_id="HRV78693.1"
                     /translation="RRTRERLGREFIIIFRLSMLDLVEDGSTFEEVVQLAQAIEAAGA
                     TLINSGIGWHEARIPTIATCVPRAGFAWVTQKLKEHVGIPLIATNRINTPEIAESILA
                     EGKADMVSMARPFLADPDFVNKAAEGRGADINTCIACNQACLDHTFSGKITSCLVNPR
                     ACHETELVIEPTTAPRNIAVVGAGPAGLAFATTAAERGHKVTLFEAGARIGGQFNIAM
                     QIPGKEEFAETLRYFGRRIEQTGVTLKLNTRVKAAELAGQFDEVVLATGIVPRVPEIE
                     GVDHPKVLGYLDVLRDRKPVGRRVAILGAGGIGFDVAEYLSHEGVSPSLAPAKFYAEW
                     GIDANYARRGGLVQPHLETAPREIVLLQRKASKVGEGLGKTTGWIHRTALKNRGVKMI
                     AGATYHRIDDAGLHVTIAGKDEVLAVDNVILCTGQEPQRALQAALVEAGMRVHLIGGA
                     DVAAELDAKRAIKQGIELAASIEKAASAPALLAGQLPAALGGAGIPLPQFDTLRIGLD
                     GQVAVVTLNRPDKANAMNLQMWQDIRAAMQWVDRTPAVRVAVLHGAGEHFCAGIDLQM
                     MMGILPTVKDACEARTRENLRNLILDLQDTLTSLERCRKPVLAAIHGACVGGGVDLIA
                     CADMRYCAAGTYFSVKEVDLGMVADVGSLQRLPRLIGEGMVRELAYTGRKLGAAEAGQ
                     IGLVNRVFDSPEALLEGVMQLARAIAAKSPLAIRGTKDMLNHARDHSVADGLDRVATW
                     NAAMLLSEDLQAAIRAGLTKQAPTFRD"
     gene            complement(2521..2862)
                     /locus_tag="P5537_11420"
     CDS             complement(2521..2862)
                     /locus_tag="P5537_11420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004306142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HRV78694.1"
                     /translation="MSSLPRCPACNSEYTYEDGDNFVCPECAHEWPKQAAADVAEAQK
                     VWKDANGNVLQDGDSVTVIKDLKVKGSSLVVKVGTKVKNIRLVEGDHDIDCKIDGIGA
                     MKLKSEFVKKN"
     gene            complement(2916..3638)
                     /locus_tag="P5537_11425"
     CDS             complement(2916..3638)
                     /locus_tag="P5537_11425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004306140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ankyrin repeat domain-containing protein"
                     /protein_id="HRV78695.1"
                     /translation="MHKDLPDHRPPMSAKLRRLALAAAFVASGLASQATLAATLDDAL
                     SAASMGDAKELVSLIQRGLDPDTVDAQGNTLLILAAREGHTAAVEALAKNRARLDYRN
                     PAGDSALMLAVLRGHEDAARALLKAGAAAAHDGWAPLHYAAFEGRDKLIDELLAAGAD
                     VNAPAPNRATPLMLAARNGHIDVVRRLLARPQTDLNALNDAGLSADAWALQNNNTDIA
                     ELIQAERKRRGIRPPAMKITIE"
     gene            complement(3619..4395)
                     /locus_tag="P5537_11430"
     CDS             complement(3619..4395)
                     /locus_tag="P5537_11430"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HRV78696.1"
                     /translation="MFVDSHCHLDFPGLAEREDEILATMAANDVGTALCISVRLEEFP
                     RVLALAERHAHLWASVGVHPDNADCEEPDLARLLALADHPRVVAIGETGLDYYWHKDA
                     PEWQRERFRVHIRAARATGKPLVIHTRNAAADTLRLMREEGAGEAGGVMHCFTESWEV
                     AEAALELGFYISFSGIVSFRNAKELKEVARRVPLDRLLIETDSPYLAPVPHRGKTNEP
                     GWVVHVAEEIARLRELSLAQVEQATTANFFRLFRHAQRPA"
     gene            complement(4481..4846)
                     /locus_tag="P5537_11435"
     CDS             complement(4481..4846)
                     /locus_tag="P5537_11435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HRV78697.1"
                     /translation="MTQAARPAVSRPSVLSLNISSKSALYAAYMPFLVNGGIFVPTPK
                     SYRLGDEVFMLLQLMDDATRHPVAGTVVWITPDGAQGGKTQGIGVQFSPDESSRVLRD
                     RIEKVLAGHLGSSRPTHTL"
     gene            complement(4843..5886)
                     /gene="holB"
                     /locus_tag="P5537_11440"
     CDS             complement(4843..5886)
                     /gene="holB"
                     /locus_tag="P5537_11440"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HRV78698.1"
                     /translation="MIHPWLQPTWARLVELGERLPHALLFVGPAGLGKRALAEALAAR
                     LLCDAPGADGHACGQCEPCLWRLSGNHPDLHRVVPEAETAAAEGEGDGEAPAKAASTQ
                     IRIDQIRELQGALTVTGHHGSRRVVLLDPAEAMNGVTANALLKLLEEPPEGCVFVLVS
                     SSPRILLPTIRSRCQQWHFSRPEAAALAGWAAHAAADARALLALGGGMPLAAERLAQG
                     GGAAMHARFVRDIGGLQADDVLRLAGQWESWLRSKDALAAGFGLPELADWMQRWVSDL
                     AVLRLGGRVRFFPAQEGVLAALAARMSVAAASACYNELAQIRKVSRHPLSLRLVLEDM
                     LMRYARAVAGARG"
     gene            complement(5883..6584)
                     /gene="tmk"
                     /locus_tag="P5537_11445"
     CDS             complement(5883..6584)
                     /gene="tmk"
                     /locus_tag="P5537_11445"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004384771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HRV78699.1"
                     /translation="MSRMPPRLPDTDMIENAPSAVASGAATPARGRFITFEGIDGAGK
                     SSQIAAVVALLQAAGVEVDQTREPGGTALGERLRELLLHEPMHLETEAMLMFAARREH
                     LAARIEPALAAGRWVVCDRFSDATFAYQVGGRGLDRAKFDALEAWVHPGLQPDLTLVF
                     DLDPVVAAARVASTGVDPDRFEREQRDFFERVRAAYLERARLAPRRICVIDAARTPDA
                     IRADVERIVRERLLP"
     gene            complement(6581..7594)
                     /gene="mltG"
                     /locus_tag="P5537_11450"
     CDS             complement(6581..7594)
                     /gene="mltG"
                     /locus_tag="P5537_11450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004327765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HRV78700.1"
                     /translation="MTRLFPRLLLLFAVLAAVAAMTAAAAWWYAHRPLALAAERADFT
                     VARGMGMRQAATVIERAGVDVDARLLALLARLTKRDARIKAGSYEVHAGITPWQLILK
                     LSDGDVTQGELLLVEGWTFRQVRQALESHPDLEPDTAGLGEAEILERIGASAKHPEGL
                     FFPDTYLFDKRSGALAVLRRAHESMQARLDKAWAERDPATPLASPYEALILASIVEKE
                     TGRPEDRGLVASVFANRLRIGMRLQTDPTVIYGLGPEFDGRLRRVHLDTDHPWNTYTR
                     AGLPPTPIAMPGEAALRAALAPEKSDFLYFVARGDGSSEFSRDLAAHNRAVNKYIRNG
                     GGG"
     gene            7736..8773
                     /locus_tag="P5537_11455"
     CDS             7736..8773
                     /locus_tag="P5537_11455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate-binding protein"
                     /protein_id="HRV78701.1"
                     /translation="MTAWTEHLARVGATLDDTARSIAFAAPADEARATETATIAVPLL
                     HLGTIRSQGPDSAAFLHNLVSNDVKHMEADTAAWNSFNSPKGRMIASFLVWTEEGGHA
                     LALSADILPAFLKKFSMYVLRSKVKLADASADTALIGLAGPQAAEVAQAAGATLPAED
                     MRQTVSAAGVRCIRLGAQRLVLAVATEAAPALFDALVAAGAVRAGTAAWQLGMIRAGL
                     PLITAPTQEEFVAQMLNYELIGGVDFHKGCYPGQEIVARTQYLGKLKKRTYRLALPAG
                     STAAPGTDVYAPDFGEQSAGKLVNVAPTADGGVEALAVIQSSSAEAGDIRVGAPDGPR
                     ASLLDLPYALG"
     gene            8828..9628
                     /locus_tag="P5537_11460"
     CDS             8828..9628
                     /locus_tag="P5537_11460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004327625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NRDE family protein"
                     /protein_id="HRV78702.1"
                     /translation="MCLIVFAWRAHPDYPLVVAANRDEYLARPAAPAHWWLDAPELLA
                     GRDLEAGGTWMGLTRSGRFAALTNYRDPSRHIAGAPSRGALVREALEDARPAPATLQA
                     VQASADNYAAFNLLVGDADRLGVLESTTGGLRMLEPGCYGLSNHLLDSPWPKLVKTRT
                     ALARKLEALPTAGPVAATEDALVASLLELLRDPAPAPDPHLPATGVSLEWERWLSPAF
                     IRAPGYGTRCSSVVLRDRAGRTRLVEWTWDVDGALRSRVEHEFGACTA"
     gene            complement(9662..10087)
                     /locus_tag="P5537_11465"
     CDS             complement(9662..10087)
                     /locus_tag="P5537_11465"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004327623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HRV78703.1"
                     /translation="MKDLHVEVRGWDEAEACVMPVRTEVFVVEQGVPAEIERDALDAV
                     CRHAIARDAGGRVIATGRLLPDGHIGRMAVLRTARGAGVGGAVLQALIAEAARRGLPE
                     VALNAQTHALAFYLRHGFEAVGEVFMEAGIPHRAMRRTV"
     gene            complement(10084..10563)
                     /locus_tag="P5537_11470"
     CDS             complement(10084..10563)
                     /locus_tag="P5537_11470"
                     /EC_number="2.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004327621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA];
                     GO_function: GO:0071972 - peptidoglycan L,D-transpeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HRV78704.1"
                     /translation="MRIRVDLGRQCLELFGTDGACIRRYAVSTGERGAGERSGSLCTP
                     RGRHRIRARIGAGAPAGAVFRGRRPTGEVWSREFAAAHPGCDWILSRILWLCGEEPGR
                     NRGGEVDTMRRYIYLHGTGDDQPMGVARSHGCVRMRNRDIIELFELVPAGTVVEIVE"
     gene            complement(10564..11028)
                     /gene="tadA"
                     /locus_tag="P5537_11475"
     CDS             complement(10564..11028)
                     /gene="tadA"
                     /locus_tag="P5537_11475"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004327619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HRV78705.1"
                     /translation="MNEEDYMRAALEQARAAGAVDEVPVGAVVVCAGEIVGRGFNQPI
                     GRHDPTAHAEIMALRDAAARLGNYRLPGCELYVTLEPCVMCSGAIMHARIARVVFGAR
                     DPKTGVAGSVLDLFAEPRLNHHATIEGGVLADECGRMLSSFFAARRGRTLVA"
     gene            11504..12106
                     /gene="xpt"
                     /locus_tag="P5537_11480"
     CDS             11504..12106
                     /gene="xpt"
                     /locus_tag="P5537_11480"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004372481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000310 - xanthine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HRV78706.1"
                     /translation="MLPDSELIRPYGPLVRRIEAEATVIGDQILKIDHFLNHRIEPSF
                     ITEMGQELAKRLVRFEPSVVLTAEASGIAPGLVVAQALDIPLVYAKKYAPQVESPAIA
                     RVIPSPTKGGETKLVLSQRYIVPTDRVVIVDDFLSNGRTAVALVEMAREAGAEVLCAS
                     FIVEKRFKHGHATIEALGVPVCTLAQVEALENGHVRLTQP"
     gene            12191..13054
                     /locus_tag="P5537_11485"
     CDS             12191..13054
                     /locus_tag="P5537_11485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDOD domain-containing protein"
                     /protein_id="HRV78707.1"
                     /translation="MSSFDTQFEAFAEQVQQELREGVTSFPTVFDLSLRIQKLADAPD
                     TSLAQIAGAVQAEPLLAAKVIRMANTLTLNPYRGQITSLGDAIQRIGLSTLRCLAFAV
                     AAEQLARDHRSRQMRLVASGLWMHSIDVAAWACAFAHHLKRPDPDAAMLAGLMLDIGQ
                     FYLLARAARYPALEGDMGRFAEVVTTWDEPVRDAVLQALDLPERIVNACAADPFANTD
                     WPPAELGDVVFLATLAAESPNPFDNLLGSRQRGELLEASVADGLDRDGFDALMSEARA
                     SRMELISAACG"
     gene            complement(13097..14050)
                     /locus_tag="P5537_11490"
     CDS             complement(13097..14050)
                     /locus_tag="P5537_11490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HRV78708.1"
                     /translation="MPLTKETRSLLDMAYRVGAPRFHELSVAQARHSAQKLHFAFRPE
                     APAVAATAEVPIPRADTSALLARLYRPFGSHVDDRLPLVIFAHGGGWCIGDVASYDVA
                     CRELANGSGCAVLSVEYRLAPEHPFPAAPEDMRLAFEWSVDNADLLGIDPARIAFAGD
                     SAGGNLAIVTALALREAEVKPAFLLLIYPSTEIRSARPSRERYADGFFLDRESLQWFF
                     ERYLPGVDTEDWRVSPMRAASLAGLPPMQVICAECDPLVDDCIAFVERVRDEGGEVAL
                     RVFEGVVHGFYTLGKLIPEAREALALSAAAVRAHLVERVQA"
     gene            14193..>14743
                     /locus_tag="P5537_11495"
     CDS             14193..>14743
                     /locus_tag="P5537_11495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate kinase 2"
                     /protein_id="HRV78709.1"
                     /translation="MNKTEETVPVADTPSTRARKTRTAPRSKNKGAPRASAAGDTAPD
                     FSSAGIEDFEIEQAIDAAQDSKLVAVKDILAHSAADPQAKTDALEAILDGASPDDIHM
                     LRRALMRADLPQSPGAHPDDELSPDWRKGGYPYRNLMSRKAYEKQKYRLQVELLKLQA
                     WVKETGQRVVILFEGRDAAGKGGT"
BASE COUNT         2237 a         5332 c         5176 g         1998 t
ORIGIN      
        1 gcgccgcacg cgcgaacgac tcgggcgcga gttcatcatc atcttccggc tgtcgatgct
       61 cgacctggtc gaggacggct ccaccttcga ggaggtggtg cagctcgcgc aggcgatcga
      121 ggccgcgggc gccacgctga tcaacagcgg catcggctgg cacgaggcgc gcatcccgac
      181 catcgccacc tgcgtgccgc gcgcgggctt cgcctgggtg acgcagaagc tcaaggaaca
      241 tgtcggcatc ccgctgatcg ccaccaaccg catcaacacg cccgagatcg ccgagtccat
      301 cctcgccgaa ggcaaggccg acatggtgtc gatggcgcgg cccttcctcg ccgacccgga
      361 cttcgtgaac aaggccgccg agggccgcgg cgccgacatc aacacctgca tcgcctgcaa
      421 ccaggcctgt ctggaccaca ccttcagcgg caagatcacc tcctgcctgg tgaacccgcg
      481 cgcctgccac gagaccgagc tggtgatcga gccgaccacg gccccgcgca acatcgccgt
      541 ggtcggcgcc ggcccggcgg gcctcgcctt cgccaccacc gccgccgagc gcggccacaa
      601 ggtcacgctg ttcgaggccg gcgcgcgcat cggcgggcag ttcaacatcg ccatgcagat
      661 ccccggcaag gaggagttcg ccgagaccct gcgctacttc ggtcgccgca tcgagcaaac
      721 gggcgtgacg ctgaagctga acacccgcgt gaaggccgcc gagctcgccg gccagttcga
      781 cgaggtcgtg ctcgccaccg gcatcgtgcc gcgcgtgccc gagatcgagg gcgtggatca
      841 tcccaaggtg ctcggctatc tcgacgtgct gcgcgacagg aagccggtgg gccgtcgggt
      901 cgccatcctg ggcgccggcg gcatcggctt cgacgtcgcc gaatacctca gccacgaagg
      961 cgtcagcccc agcctggcgc cggcgaagtt ctacgccgag tggggcatcg acgcgaacta
     1021 cgcccgacgc ggcgggctcg tgcagcccca tctggaaacc gcgccgcgcg agatcgtgct
     1081 gctgcagcgc aaggccagca aggtcggcga aggcctgggc aagaccacgg gctggatcca
     1141 ccgcaccgcg ctgaagaacc gcggggtgaa gatgatcgcg ggcgccacct accaccgcat
     1201 cgacgacgca ggcctgcacg tgacgatcgc gggcaaggac gaggtgttgg cggtcgacaa
     1261 cgtgatcctg tgcaccggcc aggagccgca gcgcgcgctg caggccgcgc ttgtcgaggc
     1321 cggcatgcgg gtgcatctga tcggcggcgc ggacgtagcc gcggagctcg acgccaagcg
     1381 tgcgatcaag cagggcatcg agctcgccgc aagcatcgag aaggccgcct ccgctcctgc
     1441 gctgctcgcc gggcagctgc ccgccgccct cgggggcgcc ggcattcccc tgccgcagtt
     1501 cgacaccctg cgcatcggtc tcgacggcca ggtcgccgtc gtcaccctga accgccccga
     1561 caaggccaac gcgatgaacc tgcagatgtg gcaggacatc cgcgccgcga tgcagtgggt
     1621 ggatcgcacg cctgcggtgc gcgtggcggt gctgcacggc gccggcgagc acttctgcgc
     1681 gggtatcgac ctgcagatga tgatgggcat cctgcccacg gtgaaggacg cctgcgaggc
     1741 gcgcacgcgc gagaacctgc gcaacctgat cctcgacctg caggacacgc tcaccagcct
     1801 ggagcgctgc cgcaagccgg tgcttgccgc catccacggc gcctgcgtcg gcggcggagt
     1861 ggatctgatc gcctgcgccg acatgcgcta ctgcgcggcg gggacgtatt tttccgtcaa
     1921 ggaggtcgac ctcggcatgg tcgccgacgt cggcagcctg cagcggctgc cgcgcctgat
     1981 cggcgagggc atggtgcgcg agctggccta taccgggcgc aagctcggcg ccgccgaggc
     2041 gggacagatc gggctggtga accgcgtctt cgacagcccc gaagccttgt tggagggcgt
     2101 gatgcagctc gcccgcgcca tcgccgccaa gtcgccgctg gccatccgcg gcaccaagga
     2161 catgctcaat cacgcccgcg accacagcgt cgccgatggc ctcgaccgcg tcgcgacctg
     2221 gaacgccgcg atgcttctgt cggaagatct gcaggctgcg atccgcgccg gtttgaccaa
     2281 gcaagcgccg acgttccggg attgagggcg gggcggttcg cggctgccgc cgctcctaca
     2341 tcgggccgcc ggagccgcgc tgttcatgta ggagcgccgg caggcgcgaa tgcggcgcct
     2401 ccgagcacga caacgcccgt cgcctccgcg ccgccgtctt cgcggctgcc gccgctccta
     2461 cagggcgccg cacgcgccgc ggtttcgtgt aggagcgccg gcaggcgcga attgcgggcc
     2521 tcagttcttc ttcacgaact ccgacttcag cttcatcgcg ccgatgccgt cgatcttgca
     2581 gtcgatgtcg tggtcgccct cgacgagacg gatattcttg accttggtgc caaccttgac
     2641 caccagggac gagcccttga ccttgaggtc cttgatcacg gtgacgctgt cgccgtcctg
     2701 cagcacgttt ccattggcgt ccttccacac cttctgcgct tcggccacgt cggctgcggc
     2761 ctgcttcggc cattcgtggg cgcattcggg gcagacgaag ttgtcgccgt cctcgtaggt
     2821 gtattcggag ttgcaggcgg ggcacctggg cagactgctc atttcgtttc ctgttggatt
     2881 ggagcgcagg cggcgcgacg gccgccagaa gggaatcact cgatggtgat cttcatcgcc
     2941 ggcggacgga tgccgcggcg cttgcgctca gcctggatca gttcggcgat gtcggtgttg
     3001 ttgttctgca gcgcccaggc atcggcggag aggccggcgt cgttgagcgc gttgagatcc
     3061 gtctgtggcc tggccagcag gcggcgcacc acgtcgatgt ggccgttgcg cgcggccagc
     3121 atcaagggcg tggccctgtt gggcgcagga gcgttgacgt cggcaccggc ggcaaggagc
     3181 tcgtcgatca gcttgtcgcg cccctcgaag gcggcgtagt gcagcggcgc ccagccgtcg
     3241 tgggccgccg cggcaccggc cttgagcagc gcgcgcgcgg cgtcctcgtg gccgcgcagc
     3301 acggccagca tcagcgcgga gtcgcccgcc gggttgcggt agtcgaggcg ggcgcggttc
     3361 ttcgccagcg cctccacggc cgcggtgtgg ccctcgcggg cggcgaggat cagcaaggtg
     3421 ttgccctgcg cgtcgacggt gtcggggtcg agcccgcgct ggatcaggct gacgagttcc
     3481 ttggcatcgc ccatgctggc ggcggagagc gcgtcgtcga gcgtggcggc gagggtcgcc
     3541 tgcgaggcga gcccgctggc gacgaaggcg gcggccagcg cgaggcggcg cagcttggcg
     3601 gacatgggcg ggcggtgatc aggcaggtct ttgtgcatgg cggaagaggc ggaagaagtt
     3661 ggcggtggtg gcttgctcga cctgcgccag ggaaagctcg cgcaggcgcg cgatctcctc
     3721 ggcgacatgc acgacccagc cgggctcgtt ggtcttgccg cggtgcggca ccggggcgag
     3781 atagggggaa tcggtctcga tcagcaggcg gtcgagcggt acgcggcgtg cgacctcctt
     3841 gagctccttc gcgttgcgaa agctcacgat gcccgaaaac gagatgtaga agccgagctc
     3901 gagcgcggcc tcggcgacct cccagctctc ggtgaagcag tgcatcaccc cgcccgcctc
     3961 gcccgcaccc tcctcgcgca tcaggcgcag ggtgtccgcg gcggcattgc gggtgtggat
     4021 gaccagcggc ttgcccgtcg cgcgcgcggc gcggatgtgc acccggaagc gctcgcgctg
     4081 ccactcgggt gcgtccttgt gccagtaata gtccagcccg gtctcgccga tcgccaccac
     4141 gcgggggtgg tcggcgagcg cgagcaggcg ggcgaggtcg ggctcctcgc agtcggcgtt
     4201 gtccggatgc acgccgaccg aggcccacag gtgggcgtgg cgctcggcga gcgcaagcac
     4261 gcgcgggaac tcctcgaggc gcacgctgat gcacagtgcg gtaccgacgt cgttggccgc
     4321 catggtggcg aggatctcgt cctcgcgctc ggcgaggccg gggaaatcga ggtgacagtg
     4381 tgaatcgacg aacatccggg tcctgggcgt attgatgaag acggcgttgt tgaagcaggt
     4441 gccacgcgtc ccgaggcggc caccacctcg agtggcgtgc tcacagcgta tgcgtgggcc
     4501 ggctggagcc gaggtggccg gcgagtacct tctcgatgcg gtcgcgcagc acccggctgg
     4561 attcgtcggg cgagaactgc acgccgatgc cctgggtctt gccgccctgc gcgccgtccg
     4621 gggtgatcca caccacggtg cccgcgaccg gatggcgggt ggcgtcgtcc atgagctgca
     4681 gcagcatgaa cacctcgtcg cccagcctgt agctcttggg cgtaggcacg aagatcccgc
     4741 cattgaccag gaagggcatg taggccgcgt agagcgccga cttggagctg atgttgagcg
     4801 acagcacgct cgggcggctg accgcggggc gggcggcttg ggtcatcctc gggctccggc
     4861 gacggcacgg gcgtagcgca tcagcatgtc ctccagcacc agcctcaggc tcagcgggtg
     4921 gcgcgagacc ttgcggatct gggcgagctc attgtagcag gcgctcgccg cggccacgct
     4981 catgcgggcg gcgagcgcgg cgagcacgcc ctcctgcgcg gggaagaagc gcacccggcc
     5041 gcccaggcgc agcaccgcca ggtcgctcac ccagcgctgc atccagtcgg cgagctcggg
     5101 caggccgaac ccggctgcga gcgcgtcctt ggagcgcagc caggactccc actgcccggc
     5161 caggcgcaac acgtcgtcgg cctgcaggcc accgatgtca cgcacgaagc gcgcgtgcat
     5221 cgcggcgccg ccaccctggg cgaggcgctc ggcagcgagc ggcatgccgc cgccgagggc
     5281 gagcagcgcg cgcgcgtcgg cggcggcatg cgccgcccag cctgccagcg cggctgcttc
     5341 gggccggctg aagtgccact gctggcagcg gctgcggatg gtgggcagca ggatgcgcgg
     5401 cgacgaggac acgagcacga acacgcagcc ctcgggcggc tcctcgagca gcttgagcag
     5461 cgcattggcg gtgacgccgt tcatggcctc cgcgggatcg agcagcacga cgcggcgtga
     5521 gccgtggtgg ccggtgacgg tgagcgcgcc ctgcaactcg cggatctggt cgatgcggat
     5581 ctgcgtggag gcggccttgg cgggcgcctc gccgtcgccc tcgccctccg ctgcggcggt
     5641 ttcggcctcg ggcaccacgc gatgcaggtc gggatggttg cccgagagcc gccacaggca
     5701 gggctcgcac tgcccgcagg cgtggccgtc ggcaccgggt gcatcgcaca gcaggcgcgc
     5761 agcgagcgcc tcggcgagcg cacgcttgcc caggccggca gggccaacga acagcagcgc
     5821 atgcggcagg cgctcgccga gttcgacgag acgcgcccag gtcggctgca gccagggatg
     5881 gatcatggca gcaagcgctc gcgcacgatg cgctcgacgt cggcgcggat cgcgtcgggc
     5941 gtgcgcgccg cgtcgatcac gcagatgcgc cgcggagcga ggcgggcccg ttcgagatag
     6001 gccgcgcgca cgcgctcgaa gaaatcacgc tgctcgcgct cgaagcggtc ggggtcgacc
     6061 ccggtggagg cgacgcgcgc ggcggcgacc accgggtcga ggtcgaacac cagggtgagg
     6121 tcgggctgca ggccgggatg cacccaggcc tcgagggcgt cgaacttggc gcgatccagc
     6181 ccgcgcccgc caacctggta ggcgaaggtg gcgtcggaga agcggtcgca caccacccag
     6241 cgcccggcgg cgagcgcggg ctcgatgcgc gcggccaggt gctcgcggcg cgcggcgaac
     6301 atcagcatgg cctcggtctc gaggtgcatc ggctcgtgca gcagcagctc gcgcaaacgc
     6361 tcgccaagcg ccgtgccgcc gggctcgcgg gtctggtcca cctcgacgcc ggcagcctgc
     6421 agcagcgcca ccacggcggc gatctggctg ctcttgccgg caccgtcgat gccttcgaag
     6481 gtgatgaagc ggccgcgggc cggcgtggcg gcgcccgaag ccacggcgga gggggcgttt
     6541 tcgatcatgt cggtgtcggg caggcgtggt ggcatgcggc tcatcccccg cctccgttgc
     6601 ggatgtactt attgacggcg cggttgtggg ccgcgaggtc gcgcgagaac tcgctgctgc
     6661 cgtcgccgcg ggcgacgaag tagaggaagt cgctcttttc gggcgcgagc gcggcgcgca
     6721 gtgcggcctc gccgggcatc gcgatcggcg tcggcggcag gccggcgcgg gtgtaggtgt
     6781 tccaggggtg gtcggtgtcg agatgcacgc ggcgcaggcg gccgtcgaac tcggggccga
     6841 gaccgtagat caccgtggga tcggtctgca gacgcatgcc gatgcgcagc cggttggcga
     6901 acaccgaggc caccaggccg cggtcctcgg gtcggccagt ctccttctcg acgatcgagg
     6961 cgaggatcag cgcctcgtag ggcgaggcca gcggcgtggc cgggtcgcgc tcggcccagg
     7021 ccttgtcgag gcgggcctgc atggactcgt gcgcgcgccg cagcaccgcg agcgcgcccg
     7081 agcgcttgtc gaagaggtag gtgtcgggga agaacaggcc ctcggggtgc ttcgcgctcg
     7141 cgccgatccg ctcgaggatc tccgcctcgc ccagcccggc ggtgtcgggc tcgagatcgg
     7201 gatgggactc gagcgcctgg cgcacctgac ggaaggtcca gccctcgacc agcagcagct
     7261 caccctgggt gacgtcgccg tcggagagct tgaggatgag ctgccagggc gtgatgccgg
     7321 catgcacctc gtagctgccg gccttgatgc gggcgtcgcg tttcgtcagc cgcgcgagca
     7381 gcgcgagcag gcgcgcatcc acgtccacgc cggcgcgctc gatgaccgtt gcggcctggc
     7441 gcatgcccat gccgcgcgcg acggtgaagt ccgcccgctc ggcggcgagc gcgagcggac
     7501 ggtgcgcata ccaccaggcc gcagccgcag tcattgcggc gacggcagcc agcacggcga
     7561 acagcaggag caggcgaggg aaaagacgcg tcatcggagg gggaagggca ggctaaatcc
     7621 ctgtcggcgc gaggggcgac cgccacgagg agggcgccta taataccgca gcacgtgccc
     7681 tcccccgcct gcggcgcgcc cccctacacc atccgagatt gcccgaaccg agaccatgac
     7741 tgcctggacc gaacacctcg cccgcgtggg cgccacgctc gacgacaccg cccgctccat
     7801 cgccttcgcc gcgcccgccg acgaagcgcg cgcgaccgag accgcgacca tcgcggtgcc
     7861 gctgctgcac ctcggcacga tccgctcgca gggcccggac tccgccgcct tcctgcacaa
     7921 cctggtgtcg aacgacgtaa agcacatgga ggccgacacc gcggcctgga acagcttcaa
     7981 ttcgcccaag ggccgcatga tcgcgagctt cctggtgtgg accgaggaag gcggccatgc
     8041 gctcgcgctc tcggccgaca tcctgccggc cttcctgaag aagttctcga tgtacgtgct
     8101 gcgcagcaag gtcaagctcg ccgacgccag cgccgacacc gcgctgatcg ggctcgccgg
     8161 cccgcaggcc gcggaggtcg cgcaggcggc cggggccacg ctccccgccg aggacatgcg
     8221 ccagacggtg tccgccgcgg gcgtgcgctg catccgcctc ggcgcgcagc gcctcgtgct
     8281 cgccgtcgcc accgaggccg cgcccgcgct cttcgacgcg ctcgtcgccg ccggcgcggt
     8341 gcgtgccggc accgcggcct ggcagctggg catgatccgc gccggcctgc cgctgatcac
     8401 cgcgcccacc caggaagagt tcgtcgccca gatgctcaac tacgaactca tcggcggcgt
     8461 ggacttccac aagggctgct accccggcca ggagatcgtg gcgcgcaccc agtacctcgg
     8521 caagctcaag aagcgcacct accgcctcgc cctgcccgcg ggcagcacgg ccgcgcccgg
     8581 caccgacgtc tatgcgcccg acttcggcga gcagtccgcc ggcaagctgg tcaacgtcgc
     8641 ccccaccgcc gacggcggcg tggaagcact cgcggtgatc cagtcgagca gcgccgaagc
     8701 gggcgacatc cgcgtcggcg cacccgacgg gccgcgcgcc agcctgctcg acctgcccta
     8761 tgcgctcggc tgatccgcag cgcggcccgg ccggcgggcc cgctcgcagc cgcaggggcg
     8821 cgccgtcgtg tgcctgatcg tctttgcctg gcgggcgcat cccgactatc cgctcgtggt
     8881 cgcggccaac cgcgacgagt acctcgcgcg ccccgccgcg cccgcgcact ggtggttgga
     8941 tgcgcccgag ctgctcgccg gccgcgacct cgaggccggc ggcacctgga tgggcctgac
     9001 gcgcagcggc cgtttcgccg cgctgaccaa ctaccgcgac cccagccgcc acatcgccgg
     9061 ggcgccttcg cgcggcgcgc tggtgcgcga ggcgctcgag gatgcccgcc cggcgcccgc
     9121 cacgctgcag gccgtccagg cgagcgcaga caactacgcc gccttcaacc tgctggtggg
     9181 cgacgctgat cggctcggcg tgctcgagag caccaccggc gggctgcgca tgctggagcc
     9241 gggctgctac gggctgtcca accacctgct cgacagcccc tggcccaagc tggtgaagac
     9301 gcgcacggcg ctcgcccgca agctcgaggc gctaccgacg gcaggcccgg tggcggcgac
     9361 cgaggacgcg ctggtcgcca gcctcctcga attgctgcgt gaccccgcgc ccgcgcccga
     9421 cccgcacctg cccgcgaccg gcgtgagcct ggaatgggag cgctggctgt cacccgcctt
     9481 catccgcgca cccggctacg gcacgcgctg cagcagcgtg gtgctgcgtg accgcgcggg
     9541 ccgcacccgc ctcgtcgaat ggacctggga cgtggacgga gcgctgcgca gccgggtcga
     9601 gcacgagttc ggcgcctgca cggcctgaac gccgcgcgca acgcctctgc aggcccagtc
     9661 gctaaaccgt gcgccgcatc gcacgatgtg gaatgcccgc ttccatgaag acctcgccca
     9721 ccgcctcgaa gccgtggcgc aggtagaagg ctagcgcgtg ggtctgggcg ttgagcgcga
     9781 cctcgggcaa tccacgccgc gccgcctcgg cgatcagcgc ctgcagcacc gcaccgccca
     9841 ccccggcgcc gcgcgccgtg cgcagcaccg ccatgcggcc gatgtggccg tcgggcaaca
     9901 ggcggccggt ggcgatcacc cggcccccgg cgtcgcgcgc gatcgcgtgc cggcacaccg
     9961 cgtcgagggc gtcgcgctcg atctccgcgg gcacgccctg ctccaccacg aagacttcgg
    10021 tgcgcaccgg catcacgcaa gcctcggctt cgtcccagcc cctcacctcg acgtgcaggt
    10081 ccttcattcg acgatctcca ccacggtgcc cgccggcacg agttcgaaca gctcgatgat
    10141 gtcgcggttg cgcatgcgca cgcagccgtg cgagcgcgcc acgcccatgg gctggtcgtc
    10201 gccggtgccg tgcaggtaga tgtagcgccg catcgtgtcc acctcgccgc cgcggttgcg
    10261 cccgggctcc tcgccgcaca gccacaggat gcgcgacagg atccagtcgc accccggatg
    10321 cgcggcagcg aactcgcgcg accacacctc gccggtcggc cggcgcccgc ggaacaccgc
    10381 gcccgcgggt gcgcccgcgc cgatgcgcgc gcggatgcgg tggcggccgc gcggcgtaca
    10441 caggctgccg ctgcgctcgc ctgcaccgcg ctcgccggtc gacaccgcgt agcggcggat
    10501 gcaggcgccg tccgtgccga agagttccag gcactgccgg ccgagatcca cgcgaatgcg
    10561 cattcaggcc accagggtgc ggccgcggcg ggcggcgaag aagctcgaca gcatgcgccc
    10621 gcactcgtcg gcgagcaccc cgccctcgat ggtggcgtga tggttgaggc gcggctcggc
    10681 gaagaggtcg agcacgctgc cggccacccc ggtcttgggg tcgcgcgcac cgaacaccac
    10741 gcgcgcgatg cgagcgtgca tgatcgcccc cgagcacatt acgcaaggct ccagggtcac
    10801 gtagagctcg cagccgggca ggcggtagtt gcccaggcgc gccgcagcat cgcgcagcgc
    10861 catgatctcg gcgtgggcgg tcgggtcgtg gcggccgatc ggctggttga agccgcggcc
    10921 gacgatttcg cccgcgcaca ccaccaccgc gcccaccggc acctcgtcga cggccccggc
    10981 cgcgcgcgcc tgctcgagcg cggcgcgcat gtagtcttct tcgttcatcg cgttcatcgt
    11041 tcggaaacgg ggccgattct agcccgaaag gtcgcgcacc gatcctcgac caccgctggc
    11101 ttcggcgcga aaccggcaga acctcgaatg acgcctcaaa ccaggaaggc cgcgaggcag
    11161 cggggccggg caggcggtcg ccaacttcag cagcgccgag gtggagggcg tcgcggggga
    11221 aacaaggcga cacctgtccg aggcgcgcag cgccgagttc gtgtcgccgc ccccgcggcg
    11281 tccgccaccg agggtagccc gaagcgcagc gcagggccgc gagtgcaggc ggcgaccgcc
    11341 cgcccggccc cgccgccgga tcggagcggg aatcacgatc tgtgccgaaa tcacgatcga
    11401 cccgcgttcg cgcctgccgg cgctcctaca acgccgccgc cttcggctag aatccgcccg
    11461 tccagccccc ggcccggggg catttccgtt tacggacccg cgcatgcttc ccgattccga
    11521 actcatccgc ccctacggcc cgctggtgcg ccgcatcgaa gccgaagcca ccgtcatcgg
    11581 cgaccagatc ctcaagatcg accacttcct caaccaccgc atcgagccca gcttcatcac
    11641 cgagatgggc caggagctcg ccaagcggct ggtgcgcttc gagcccagcg tggtcctcac
    11701 cgccgaggcc agcggcatcg cccccggcct ggtggttgcc caggcgctcg acatcccgct
    11761 ggtgtatgcg aagaagtacg cgccccaggt cgagtccccc gcgatcgcac gcgtgatccc
    11821 ctcgcccacc aagggcggcg agaccaagct cgtgctgtcg cagcgctaca tcgtgcccac
    11881 cgaccgcgtg gtcatcgtcg acgacttcct ctccaacggc cgcaccgcgg tggcgctcgt
    11941 cgagatggcc cgcgaggccg gcgccgaggt gctgtgcgcg agcttcatcg tcgagaagcg
    12001 cttcaagcac ggccacgcca ccatcgaggc gctcggcgtg ccagtgtgca cgctcgccca
    12061 ggtcgaggcg ctcgagaacg gccacgtccg cctcacgcag ccctgaagcc gaggtcgttc
    12121 gtgggatttg cacgcgcagg catgcccgca tgcgcataga ctgcgccaat cccatgaacg
    12181 gaaccggccc atgagctctt tcgacaccca attcgaagcc ttcgccgaac aggtccagca
    12241 agaactgcgc gagggcgtga cgagctttcc caccgtcttc gacctctcgc tgcgcatcca
    12301 gaagctggcc gacgccccgg acacctcgct cgcgcagatc gccggcgcgg tgcaggccga
    12361 gcccctgctc gccgccaagg tcatccggat ggccaacacg ctgacgctga acccctaccg
    12421 cggccagatc accagcctgg gcgatgccat ccagcgcatc ggcctgtcca cgctgcgctg
    12481 cctcgccttc gcggtcgccg ccgagcagct cgcgcgcgac caccgctcgc gccagatgcg
    12541 cctggtcgcc agcgggctgt ggatgcactc gatcgacgtg gcggcatggg cctgcgcctt
    12601 cgcccaccac ctcaagcgcc ccgaccccga tgccgcgatg ctggccggcc tgatgctcga
    12661 catcggccag ttctacctgc tggcgcgtgc ggcccgctac ccggcgctgg aaggcgacat
    12721 gggtcgcttc gccgaggtgg tcacgacctg ggacgagccg gtgcgcgatg ccgtgctgca
    12781 ggcgctcgac ctgcccgagc gcatcgtcaa cgcctgcgcc gccgacccct tcgccaacac
    12841 cgactggccg cccgccgagc tcggcgacgt ggtcttcctc gccaccctcg cggcggaatc
    12901 gcccaacccc ttcgacaacc tgctcggcag ccgccagcgc ggcgaactgc tcgaggcgag
    12961 cgtggccgac ggcctcgatc gcgacggctt cgacgcgctg atgtcggagg cgcgcgccag
    13021 ccgcatggag ctgatctccg ctgcctgcgg ctgaggaccg gctgcccgca ccgctacgcg
    13081 acggccgacg tcgcgctcag gcctgcacgc gctccaccag atgggcgcgc acggccgccg
    13141 cagacagcgc cagcgcctca cgcgcctccg ggatgagctt gcccagggtg tagaagccgt
    13201 gcaccacgcc ctcgaagacg cgcagcgcca cctccccgcc ttcgtcgcgc acgcgctcga
    13261 cgaaggcgat gcaatcgtcg accaatggat cgcattcggc acagatcacc tgcatcggcg
    13321 gcagcccggc aagcgaggcc gcgcgcatcg gcgacacccg ccagtcctcc gtgtccacgc
    13381 cgggcaggta gcgctcgaag aaccactgca gcgactcgcg atcgaggaag aagccgtcgg
    13441 cgtagcgctc gcgcgagggc cgcgcgctgc ggatctcggt gctcggatag atcagcagca
    13501 ggaaggccgg cttcacctcg gcctcgcgca gggccagcgc ggtgacgatc gccaggtttc
    13561 cgcccgcgct gtcgccggcg aaggcgatgc gcgccgggtc gatgccgagc aggtcggcgt
    13621 tgtcgaccga ccactcgaag gcgagacgca tgtcctcggg cgccgcagga aaaggatgtt
    13681 ccggcgcgag ccggtactcc accgacagca ccgcgcagcc cgaaccattg gcgagctcgc
    13741 ggcaggccac gtcgtagctc gccacgtcgc cgatgcacca gccaccgccg tgcgcgaaga
    13801 tcaccagcgg caggcggtcg tccacatgac tgccaaaggg ccggtaaagg cgggcgagca
    13861 gcgccgaggt gtcggcgcgc gggatcggca cctcggcggt cgcggccacc gcgggcgcct
    13921 cgggccggaa ggcgaagtgc agcttctgcg ccgaatggcg cgcctgcgcc accgagagct
    13981 cgtggaagcg gggcgcgccg acacggtagg ccatgtcgag cagggaacgg gtttctttgg
    14041 tcagcggcat gatcgagaaa gtggagcaat ctgccccggc cacgacgggc tgcgggcgaa
    14101 gtgcgcgatt ctacccgccc cgcccgacga cgcacgtgcc gagcgggatg cggaggatta
    14161 gaattcgttg aaaaccaggg agaaggaaga tgatgaacaa gaccgaggaa accgtcccgg
    14221 tagcggacac cccctccacc cgcgccagga agacgcgcac cgctccgcgc tcgaagaaca
    14281 agggcgcgcc gcgtgcgagc gccgccggcg acaccgcacc cgacttcagc agcgccggca
    14341 tcgaggactt cgagatcgag caggcgatcg acgcggcgca ggactccaag ctcgtcgccg
    14401 tcaaggacat cctcgcccac tcggcagccg acccgcaggc gaagaccgat gccctcgagg
    14461 ccatcctcga cggcgcctcc cctgacgaca tccacatgct gcgccgcgcg ctgatgcgcg
    14521 ccgacctgcc gcagagcccg ggcgcccacc cggacgacga gctctcgccc gactggcgca
    14581 agggcggcta cccctatcgc aacctcatgt cgcgcaaggc ctacgagaag cagaagtacc
    14641 gcctgcaggt cgagctgctc aagctgcagg cctgggtcaa ggagaccggc cagcgcgtgg
    14701 tgatcctgtt cgagggccgc gacgccgccg gcaagggcgg cac
//
LOCUS       DAOTIN010000076        14738 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_4892_length_14738_cov_9.480896, whole genome shotgun sequence.
ACCESSION   DAOTIN010000076 DAOTIN010000000
VERSION     DAOTIN010000076.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 14738)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 14738)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14738
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4892_length_14738_cov_9.480896"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(46..873)
                     /locus_tag="P5537_11500"
     CDS             complement(46..873)
                     /locus_tag="P5537_11500"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002930813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051073 - adenosylcobinamide-GDP
                     ribazoletransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HRV78710.1"
                     /translation="MRYQLELFFTALGFFTRIPVPAWVPWSAERMNHAARYFALVGWV
                     VGAVGALGYLALAWLLPPAVAVILSMALTIRLTGAFHEDGFADSCDGLGGGWDKAQVL
                     AIMKDSRIGSYGTIGMVLMLLAKAAALVELAAPSAVAPLAGSAASVPPADLLPPGVGV
                     ALALLVAHPLSRLAATVVMHRLPYVRADDSAKSAAVARPLAPAELALAATCGLLPLLL
                     LPPAGAFCALLAAMVATAWTARLFLRRLGGYTGDLLGATQQASELSIYLGLLVVAPL"
     gene            complement(873..1934)
                     /gene="cobT"
                     /locus_tag="P5537_11505"
     CDS             complement(873..1934)
                     /gene="cobT"
                     /locus_tag="P5537_11505"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004306936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008939 -
                     nicotinate-nucleotide-dimethylbenzimidazole
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HRV78711.1"
                     /translation="MKPYAIASPDPLLSAAIRHKIDRKTKPHGALGRLEGLAHQIALV
                     QQTLDPELRQPHIVVFAGDHGAARAGVSAYPQDVTWQMVENFLAGGAAINVFTRQLGL
                     DLTVVDAGVNHDFGKRAGLIDAKIAPGTANYIEEPAISAAQRDAALERGRGIAHALAD
                     NGCNCIGLGEMGIGNTASASLLTHCLVGAEHDAELYTVTGRGTGLDDPGLYRKRSLLA
                     QALQRGGRTHDPLEVLVQYGGLEIAMMAGAILGAAERRMLVLVDGFIVTSALLVAHGL
                     APAVLSYCVFAHRSQEPGHRVQLDFLQAEPLMELDLRLGEGTGAALAFPLVQAAVDFM
                     NEMASFESAGVSDQARSPG"
     gene            complement(1931..2560)
                     /locus_tag="P5537_11510"
     CDS             complement(1931..2560)
                     /locus_tag="P5537_11510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Uma2 family endonuclease"
                     /protein_id="HRV78712.1"
                     /translation="MGLPAPKHKMTLEDFLAWEAEQPERWEFFNGEAFMMAGGADVHN
                     AISLNTAFALRQTLRGTRCNVFMSDVRLRLAESDDLFYPDVFVTCSDADRARRQVKED
                     PTLIAEVLSPSTEAYDRGDKFAAYRRFAGLKTVLFLSQDRAHVECFTRGDDGRWVLSE
                     ASGETARLALPAFDFELALADLYRDLPDAEATDPAPVLPPSTPRPPPAA"
     gene            complement(2596..3144)
                     /gene="cobU"
                     /locus_tag="P5537_11515"
     CDS             complement(2596..3144)
                     /gene="cobU"
                     /locus_tag="P5537_11515"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004306939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0043752 - adenosylcobinamide kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HRV78713.1"
                     /translation="MTCELILGGARSGKSREAERRAADSGLAVTVIATAEALDEEMAA
                     RIRRHQADRPAGWRTVEAPLALAEALRREAAAERCLIVDCLTLWLSNLLADAHTLPAG
                     ATAEDLPRFRHERDGLLAALPTLPGRIVLVANEVGLGLVPETPLGRLFRDEAGRLNQM
                     VASACRRVVFVAAGLPLVLKEG"
     regulatory      3237..3476
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            3587..>4095
                     /locus_tag="P5537_11520"
     CDS             3587..>4095
                     /locus_tag="P5537_11520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor plug domain-containing
                     protein"
                     /protein_id="HRV78714.1"
                     /translation="MAKGVLTMKIRLSALVSTCALACSVAPAVHAADAQLGHVVVTAT
                     RQPISADAALASVDVIERDEIARAGHSSLLGLLSSRPGVQMARNGGPGSSGSIFIRGA
                     NSGHTLVLVDGVRIGSATSGSPVLETIPLELIERIEILRGPGSALYGADALGGVIQVF
                     TRKGREGFQP"
     assembly_gap    4096..4195
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <4196..4792
                     /locus_tag="P5537_11525"
     CDS             <4196..4792
                     /locus_tag="P5537_11525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HRV78715.1"
                     /translation="FPVECYGAWGCFGGNPDLAPEEALNRELGVAWERNGVGVDLTYF
                     NNRIRNLIDWSTGIASNVGRANIQGVEAALSAALGDYRLRASVDLLDAEDDKTGDQLG
                     RRARVGGALALERAVGAWTWGVEWNGKGRRYDQVPNAVSNRLGGYGLVDAYAHYAMAR
                     DWSVEVRANNLLDKDHELAKGFATPGRSAFVALRYAMH"
     gene            4844..5830
                     /locus_tag="P5537_11530"
     CDS             4844..5830
                     /locus_tag="P5537_11530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HRV78716.1"
                     /translation="MRCRRSPPAIAAVLLSAAAVALLWALVAGDLPVGATDVVAALVG
                     GDGMGATVIRELRLPRALAAFACGGLLATAGALMQVLLRNPLADPYILGISGGAAVGA
                     LGAMVLGAAMFWVDVSAFAGALAAMLLVFGLAHGDGSWTQTRLLLTGVIVAAGCGAAV
                     SLMLALAPDTRVMSMLFWMMGDASAASRPWPALAVLALALVAVMPFARDLNVLARGEV
                     VARALGVRVGHLRIALYVLASLLTATAVTLVGSVGFVGLVVPHLVRLALGNDQRVLIP
                     AAALAGGTLLTLADTAARTVMAPQQLPVGVLTALIGVPVFLFLLSRSPRGKA"
     gene            5827..6636
                     /locus_tag="P5537_11535"
     CDS             5827..6636
                     /locus_tag="P5537_11535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV78717.1"
                     /translation="MNAARRALPVDAAPLLEAERLALRVGERWLCCEFSLSLAAGECL
                     VLLGPNGAGKTTLLHTLAGLREPTVGEVRIGGLPYAAWPALEAARFRGLLAQQQPDPF
                     AASVLETVLVGRHPHLGRWGWEGPQDVAIARAALESVGLAGFEQRDVQTLSGGERQRV
                     AIATLLTQAPRLFLLDEPLNHLDLHHQIAALDLFQRLVREDGAGRGSVLVLHDINLAA
                     RYADHIILLDGRGGVMAGNRDAVLRADLLSQAFGHPLRRIEHAGRAVFLPD"
     gene            6746..6985
                     /locus_tag="P5537_11540"
     CDS             6746..6985
                     /locus_tag="P5537_11540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004306946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HRV78718.1"
                     /translation="MSRLYSPQQAAELLVGRRKALGLSQAEVAARLGISQNRLSELET
                     RPERLTFDRLLALAGVLGLELALGERKPVEAEGEW"
     gene            6979..8352
                     /locus_tag="P5537_11545"
     CDS             6979..8352
                     /locus_tag="P5537_11545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HipA family
                     toxin"
                     /protein_id="HRV78719.1"
                     /translation="MVGPGKRTQARVLDVWINGLRVGQWQVTAQGEDRFRYAPEWLES
                     AEARPLSLSLPMPLDAAAPALRGLRVRNYFDNLLPDSEQIRMRLQARFRTPGRGVFEL
                     LQAIGRDCVGAVQLLPEGQGPEGVFRIDAEPLDEADVERLLRAAVAPVRAFGEVATDL
                     DDFRISIAGAQEKTALTRHAGRWCRPLGATPTTHIFKLPLGLVGNRQADMRTSVENEW
                     LCARLLAAFGLPVAQCEIEHFGAQKVLVVERFDRRLSATGDYWLRLPQEDFCQATATP
                     PALKYEADGGPGLLDLARILQGSVRRDDDLRIVLKAQLLFWMLAASDGHAKNFSIFLL
                     AGGRYRLAPLYDVLSAWPVAGTGENRLDPARLRLAMALRGRNAHYRLRDIQRRHFNAM
                     AHRCGLGADMEDIVEDVLAQLDPVLDKLGAELPAGFPEDVFATIAAGMRASARRLQNQ
                     KRTIDPT"
     gene            8349..8957
                     /gene="cobO"
                     /locus_tag="P5537_11550"
     CDS             8349..8957
                     /gene="cobO"
                     /locus_tag="P5537_11550"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008817 - corrinoid adenosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="HRV78720.1"
                     /translation="MTQTPDRDTRHNARMVRKKDVVDDRIAAAQAERGVLLVNTGNGK
                     GKSSAGFGLVARALGHGMRVGVVQFIKGRSDTGEEAFFRTQPGVAWHVMGEGFTWETQ
                     DRARDVATAAAAWAVAREMLQNPEVGLVVLDELNIALKYQYLDVDRVIADLRARPPMQ
                     HVVVTGRGAPPALVEAADTVTDMTPVKHAFAAGVKAMPGMEW"
     gene            8960..>9798
                     /gene="cobA"
                     /locus_tag="P5537_11555"
     CDS             8960..>9798
                     /gene="cobA"
                     /locus_tag="P5537_11555"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018991823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004851 - uroporphyrin-III
                     C-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0019354 - siroheme biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HRV78721.1"
                     /translation="MAVPDLAVHRPGPLPGWVYLVGAGPGDPELFTLRGARLVAGADV
                     IVYDNLVAPPILELAPVEAERIYVGKKAADHSLPQDEINLLLLKLARENKRVVRLKGG
                     DPFIFGRGGEEMELLVEAGIHVEVVPGVTAAAGVSAYAGIPLTHREHAQSVVFATGFL
                     KEGKIDLDWPMLARPQQTVVIYMGISRLADICAQLVAHGLPPSTPAGVIERGTTHAQR
                     VVVADLATLARRVLEEGVRPPSLTVVGSVVGLYPKLAWFEPEDQPKASPLPHAGCAVV
                     HGKG"
     assembly_gap    9799..9898
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <9899..11096
                     /locus_tag="P5537_11560"
     CDS             <9899..11096
                     /locus_tag="P5537_11560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011767272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042242 - cobyrinic acid a,c-diamide
                     synthase activity [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HRV78722.1"
                     /translation="RLGRRVRVFKCGPDFLDPQIHAVASGAPVHNVDLGMCGEADIAW
                     RLHAAARESDLILVEGVMGLYDGAPSGADIARRFGIPVMAVIDARAMAQTFGAVAYGL
                     AHYQPGLPFAGVLANHVGSARHADMLRESLPEGMRWFGAVMRDAEAALPERHLGLLQA
                     AEIEDLGARLDRVADHLARTGAAELPAVVAFPAVAAPAIPPLLAGKRVAIARDAAYGF
                     LYPANIDTLRALGAELAFFSPLAGEGLPTQCDAVWLPGGYPELHGAALAANAGLWTDL
                     RAHVAAGKPVLAECGGLMSLLEAIVDKAGVEQTFAGLLPGRAVMQSRLAALGLQEVDL
                     PGGRLSGHTFHYSRTETPLAPWLRARRPDGGEGEAIYRCGPITASYVHFWFPSNPVAA
                     AGLFGA"
     assembly_gap    11222..11321
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(11440..12339)
                     /locus_tag="P5537_11565"
     CDS             complement(11440..12339)
                     /locus_tag="P5537_11565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator ArgP"
                     /protein_id="HRV78723.1"
                     /translation="MIDQRLLAFEAVLQEGGFERAARRLSLTQSAVSQRVKLLEAELG
                     QVLLVRSKPVRPTPAGRRLLPYLAQLRLMEAEARRALSPRQADGPLRLAVGVNADSLA
                     TWFIGAVAEVVRDEGIVLDCVVDDQDHTHALLADGEVLGCVSTRADPMRGCAAVRLGA
                     MPYLCAGSPAFRARWFPHGLTPAALAQAPAIVFGRHDDMHEAFLLHHFGLDARRYPHH
                     VVPSSEGFMAFAVAGLGYGFIPEIQARVHLARGELVDLAPEREEVVLYWHHWQVQSPV
                     MARLARAIGDAAGKALAAPTPAA"
     gene            12882..13487
                     /locus_tag="P5537_11570"
     CDS             12882..13487
                     /locus_tag="P5537_11570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysE/ArgO family amino acid transporter"
                     /protein_id="HRV78724.1"
                     /translation="MSNVYFNGFLLTLGLIMAIGAQNAHVLRQGLRGEHVLLTIGVSA
                     ACDILLIGLGIAGVGSLFVANPDLMTVARYGGAAFLVWYGTRALLSALRGGRALDLAE
                     HKRMSRGQALLAAAGFSLLNPHAYLDTVVLLGSIGSQQAEDLRPLFAAGAISASIVWF
                     LLLGYGARLLAPLFAKPVAWRVLDALVALMLWAIAASLLLA"
     gene            13777..14667
                     /gene="asd"
                     /locus_tag="P5537_11575"
     CDS             13777..14667
                     /gene="asd"
                     /locus_tag="P5537_11575"
                     /EC_number="4.1.1.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586105.1"
                     /note="Phosphatidylserine decarboxylase is synthesized as
                     a single chain precursor. Generation of the pyruvoyl
                     active site from a Ser is coupled to cleavage of a Gly-Ser
                     bond between the larger (beta) and smaller (alpha chains).
                     It is an integral membrane protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004609 - phosphatidylserine decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="archaetidylserine decarboxylase"
                     /protein_id="HRV78725.1"
                     /translation="MSERLAVALQYALPKRLLTQLAGKLAGLEGGKVTTAVIRWFAKR
                     YGVNMAEAANPDPASYASFNQFFTRPLREGARPIADADFVCPVDGAISQFGPIEFDQV
                     FQAKGHFYSTTALVGGDRALAARFESGDFATIYLSPRDYHRIHMPCAGRLTQMIYVPG
                     ELFSVNPATARGVPGLFARNERVVCVFEGEFGPFVMVLVGATIVGSMATVWHGVVNPP
                     RRPDIAKRSYAEGEVMLEQGAEMGRFLLGSTVVMLFPKDTLRFGSDWAPGGPVRMGEP
                     MARAKSSAPSDGAPAQVDAP"
BASE COUNT         1983 a         5034 c         5265 g         2156 t
ORIGIN      
        1 acagcgtcaa atgccgcgcc gccgtgttcg cggctgccgc cgctcctaca ggggcgccac
       61 cacgagcagg ccgaggtaga tggagagctc gctcgcctgc tgggtggcgc cgagcaggtc
      121 gccggtgtag ccgccgagcc ggcgcaggaa gaggcgcgcg gtccaggccg tcgccaccat
      181 ggcggcgagc agggcgcaga acgcgccggc aggcggcagc agcagcagcg gcagcaggcc
      241 gcaggtggcg gccagcgcga gctcggccgg cgcaagtggg cgcgcgacgg cggccgactt
      301 ggcagagtcg tcggcgcgca cgtagggcag gcggtgcatc accacggtgg cggccaggcg
      361 cgacagcgga tgggcgacga gcagggcgag cgccacgccc acgcctggcg gcaagaggtc
      421 ggcaggcgga acggacgcag ccgagccggc gagtggggcc accgccgacg gggcagccaa
      481 ctccaccagc gccgccgcct tggcgagcag catcagcacc atgccgatgg tgccgtagct
      541 gccgatgcgc gagtccttca tgatcgccag cacctgcgcc ttgtcccagc cgccgccgag
      601 gccgtcgcag ctgtcggcga agccgtcctc gtggaaggcg ccggtcaggc ggatggtgag
      661 cgccatcgac aggatcaccg ccacggcggg cggcagcagc caggcgaggg cgaggtagcc
      721 aagcgcgccg actgcgccca ccacccagcc cacgagcgcg aagtagcgcg ccgcgtggtt
      781 catgcgctcg gccgaccacg gcacccaggc gggcaccggg atgcgggtga agaagccgag
      841 cgcggtgaag aagagttcga gctggtagcg catcaccccg gactgcgggc ctggtcgctc
      901 accccggcgg actcgaagct cgccatctcg ttcatgaaat cgaccgccgc ctgcacgagc
      961 gggaaggcga gcgccgcgcc ggtgccttcg cccaggcgca ggtcgagctc catcagcggt
     1021 tcggcctgca ggaagtcgag ctgcacgcgg tggccgggct cctgcgagcg gtgcgcgaac
     1081 acgcagtagg acagcaccgc cggcgccagg ccgtgggcga cgaggagcgc cgaagtgacg
     1141 atgaagccgt cgaccagcac cagcatgcgt cgctcggccg cgccgaggat cgcgcccgcc
     1201 atcatggcga tctcgaggcc gccgtactgc accagcacct ccagcgggtc gtgtgtccgc
     1261 ccgccgcgct gcagcgcctg ggcgagcagg ctgcgcttgc ggtagaggcc ggggtcgtcg
     1321 aggccggtgc cgcggccggt gacggtgtac agctcggcgt cgtgctcggc gcccaccagg
     1381 cagtgggtga gcagcgaggc cgacgcggtg ttgccgatgc ccatctcgcc caggccgatg
     1441 cagttgcagc cgttgtcggc gagcgcgtgg gcgatgccgc gcccgcgctc gagcgctgcg
     1501 tcgcgctgcg ctgcgctgat cgcaggctct tcgatgtagt tggccgttcc gggcgcgatc
     1561 ttggcgtcga tcagccctgc gcgcttgccg aagtcgtggt tgacgcctgc gtcgacgacg
     1621 gtgaggtcca gcccgagctg gcgggtgaag acgttgattg ccgcgccgcc ggcgaggaag
     1681 ttctccacca tctgccaggt cacgtcctgc ggataggccg acaccccggc gcgcgccgcg
     1741 ccatggtcgc cggcgaagac gacgatgtgc ggctggcgca gctcgggatc cagggtctgc
     1801 tggaccagcg cgatctggtg cgcgagcccc tccaggcggc cgagcgcgcc gtgcggcttg
     1861 gtcttgcggt cgatcttgtg gcggatcgcg gcggagagca ggggatcggg cgaggcgatg
     1921 gcgtagggct tcatgcggcg gggggcgggc gtggtgtgga gggagggagg acgggcgcgg
     1981 ggtcggtggc ttccgcgtcc ggcaggtcgc gatagaggtc ggcgagcgcg agctcgaagt
     2041 cgaaggcggg cagggcgagg cgggccgttt cgccgctcgc ctcgctcagc acccagcgcc
     2101 cgtcgtcgcc gcgggtgaag cactcgacgt gggcacggtc ctgcgacagg aagagcacgg
     2161 tcttcagtcc tgcaaagcgg cgataggcgg cgaacttgtc gccgcggtca taggcctcgg
     2221 tcgagggcga cagcacctcg gcgatgaggg tcgggtcttc cttgacctgg cggcgcgcgc
     2281 ggtcggcgtc ggagcatgtg acgaagacgt cggggtagaa gaggtcgtcc gattcggcca
     2341 ggcgcaggcg gacgtcggac atgaagacgt tgcagcgcgt gccacgcagg gtctggcgca
     2401 aggcgaaagc cgtgttgagg ctgatcgcgt tgtggacgtc cgcccccccc gccatcatga
     2461 aggcctcgcc gttgaagaac tcccagcgct cgggctgctc cgcctcccag gccaggaagt
     2521 cttccagcgt catcttgtgc ttcggtgcag gcagccccac agccctctcc cggaaagtgt
     2581 gcttcgcccc gaagtttagc cttccttcag caccagcggc aggccggcgg cgacgaagac
     2641 aacccgacgg catgcgctcg ccaccatctg gttgagacgt ccggcctcgt cgcggaacag
     2701 ccgcccgagc ggcgtctccg gcaccaggcc gagccccacc tcgttggcga cgaggacgat
     2761 gcggccgggc agcgtcggca gcgcggccag cagcccgtcg cgctcgtggc ggaaacgcgg
     2821 caggtcctcg gccgtggcgc ctgcgggcag ggtgtgggcg tcggcgagca ggttggagag
     2881 ccacagcgtg aggcagtcga cgatcaggca gcgctcggcc gcagcctcgc gccgcagcgc
     2941 ctcggcgagc gccagcggag cctcgaccgt gcgccagccc gccggccggt cggcctggtg
     3001 gcggcggatg cgtgccgcca tctcctcgtc gagcgcctcg gcggtggcga tcaccgtcac
     3061 cgccaggccg gaatcggcgg cacgccgttc ggcctcgcgg ctcttgcccg agcgcgcgcc
     3121 gccgaggatg agttcgcatg tcatcgtctt gcctggcctt gcatggtgaa ttgcctgtct
     3181 ctttttgcag tgcacgatac tgccccgtac ggtatcatcc gcccccactg ccccggaagg
     3241 ggcaacgcgt tatcggtgcc catgggcgtt tcttgccccg ggttaaacgg gaaacaggtg
     3301 cgcggcccct cgcaaacgag gccgcaatgc ctgtgctgcc cccgcaacgg taagtgcgcg
     3361 caaggtgcgt catgcagcca ctgggcatcc atgtccggga aggcgaccca cccgtccggc
     3421 catcaggccg gcacagcgca cgagcccgga gaccggccgg aacgcggatt ggcggatgtg
     3481 ccgcggggtg gcggcgacgg gcgcggtttg ttctctgctc tcttcggctc gactcggctc
     3541 gcggtgcgtc catgtgaagt tgccatggcg tgcggggacg cgcggcatgg cgaagggagt
     3601 tctgacaatg aaaatccgtc tttccgcgct cgtttccacg tgcgcgcttg cctgttccgt
     3661 cgcgccagcc gtccatgcgg ccgatgccca actcggccac gtcgtcgtga ccgccacccg
     3721 ccagccgatc agcgccgatg cggcgctcgc cagcgtcgat gtcatcgagc gcgacgagat
     3781 cgcccgcgcc ggacactcca gtctcctcgg cctgctgtcc tcgcgacccg gcgtgcagat
     3841 ggcacgcaat ggcggccccg gttcgagcgg cagcatcttc atccgcgggg cgaattccgg
     3901 acacacgctc gtgctggtcg acggggtgcg catcggctcc gccaccagcg gctctccggt
     3961 gctggagacg atcccgctcg aactcatcga gcggatcgag atcctgcgcg gccccggcag
     4021 cgcgctgtac ggcgcggacg cgctcggtgg cgtgatccag gtgttcaccc gcaagggccg
     4081 cgagggcttt cagccnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4141 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnttccc
     4201 ggtcgagtgc tacggtgcct ggggctgctt cggcggcaat cccgacctcg cgcccgagga
     4261 ggcgctcaac cgcgagctgg gcgtggcctg ggagcggaac ggcgtcggtg tcgacctgac
     4321 ctacttcaac aaccgcatca ggaacctcat cgactggagt accggcatcg cctccaatgt
     4381 gggcagggcc aacatccagg gggtcgaggc ggcgctgtcc gcggcgctcg gcgactaccg
     4441 gctgcgcgcc agcgtcgacc tgctcgacgc ggaggacgac aagaccggcg atcagctcgg
     4501 tcgccgcgcg cgcgtcggcg gcgcgctcgc gctggagcgt gcggtgggcg cgtggacctg
     4561 gggggtggag tggaacggca aggggcggcg ctatgatcag gtgccgaacg cggtgtccaa
     4621 ccgcctcgga ggttacggtc tggtcgatgc ctacgcccac tacgccatgg cgcgcgactg
     4681 gagcgtcgaa gttcgtgcca acaatcttct cgacaaggac catgagcttg cgaaggggtt
     4741 cgcaacaccg gggaggagtg ccttcgtcgc gttgcgctac gcgatgcact gaccggcgat
     4801 gcctgccgtc gccctgcgcg gggagtcgcg cttgagtccg gccatgcgct gcaggcgttc
     4861 gccgccggcg atcgcagcgg tgctgctgtc cgccgcggcg gtggccttgt tgtgggcgct
     4921 ggtcgccggc gatcttcccg tcggggcgac cgatgtcgtc gccgcgctgg tcggcggaga
     4981 cggcatgggt gcgaccgtga ttcgcgaact ccgcctcccc cgcgccctcg ccgccttcgc
     5041 ctgcggcggc ctgctcgcga ccgccggcgc cctcatgcag gtgctgctgc gcaatccgct
     5101 cgccgacccc tacatcctcg gcatctcggg cggggcggcg gtgggggcgc tgggggcgat
     5161 ggtgctcggg gcggcgatgt tctgggtgga cgtgtcggcc tttgccgggg cgctggcggc
     5221 gatgctgctc gtcttcgggc tcgcccacgg tgacggcagc tggacgcaga cgcggctgct
     5281 gctgaccggc gtgatcgtcg ccgccggctg cggcgcggcg gtgtcgctga tgctggcgct
     5341 ggcgcccgac acgcgggtga tgtcgatgct gttctggatg atgggcgacg ccagcgcggc
     5401 gtcgcggccg tggccggcgc tggcggtgct ggcgctggcg ctggtcgcgg tgatgccctt
     5461 cgcgcgcgac ctcaacgtgc tcgcgcgcgg cgaggtcgtg gcgcgcgcgc tcggcgtgcg
     5521 cgtcggccat ctgcgcatcg cgctctacgt gctcgcctcg ctgctcaccg ccacggcggt
     5581 gacgctggtg ggctcggtgg gcttcgtcgg cctggtggtg ccgcacctgg tgcggctggc
     5641 gctcggcaac gaccagcgcg tgctgatccc cgccgcggcg ctcgccggcg gcaccctgct
     5701 gaccctggcc gacaccgccg cgcgcaccgt gatggcgccg cagcagctgc cggtgggcgt
     5761 gctcaccgcg ctgatcggcg taccggtctt cctcttcctg ctctcgcgca gcccgcgcgg
     5821 caaggcatga acgccgcccg ccgcgccttg cccgtggacg ccgccccgct gctcgaggcc
     5881 gagcgcctcg cgctccgggt gggcgagcgc tggctgtgct gcgagttcag cctgagcctg
     5941 gcggcgggcg agtgcctggt gctgctcggc cccaacggcg cgggcaagac cacgctgctg
     6001 cacaccctgg ccgggctgcg cgagcccacg gtgggcgagg tgcgcatcgg cgggctgccc
     6061 tatgcggcgt ggccggcgct ggaggcggcg cgctttcgcg gcctgctcgc gcagcagcag
     6121 cccgacccct tcgcggccag cgtgctcgag accgtgctgg tcggccgcca tccgcacctc
     6181 gggcgctggg gctgggaggg gccgcaggac gtcgcgatcg cgcgtgcggc gctggagtcg
     6241 gtaggcctgg ccggcttcga gcagcgcgac gtgcagaccc tgtccggggg cgaacgccaa
     6301 cgcgtggcga tcgcgaccct gctcacacag gcgccgcgcc tcttcctgct cgacgagccg
     6361 ctcaaccatc tcgacctgca ccaccagatc gctgcgctcg atctcttcca gcgcctggtg
     6421 cgcgaggacg gcgccgggcg cggcagcgtg ctggtgctgc acgacatcaa cctcgccgcg
     6481 cgctacgccg accacatcat cctgctcgac ggccgcggcg gcgtgatggc gggcaaccgc
     6541 gacgccgtgc tgcgcgccga cctgctcagc caggccttcg gccacccgct gcggcggatc
     6601 gagcacgcgg ggcgggcggt gttcctgccg gattgagcgg ggcggctccg gattggctgc
     6661 agcgctcgat atcgggattt tcgatttctt gcttttatcg agaaaggcga tatcctggat
     6721 ttatcgagat catcgatacg acgccatgtc cagactctac tctccgcaac aagccgccga
     6781 actgctcgtc ggccggcgca aggcactcgg tctgtcgcaa gccgaggtcg cagcgcggct
     6841 cggcatcagc cagaaccggc tctccgaact ggagacacgc ccggagcgcc tgaccttcga
     6901 ccgtctgctc gcgctcgcgg gcgtgctcgg gctggaactg gccctcggtg agcgcaaacc
     6961 cgtcgaggcg gaaggcgaat ggtaggcccg gggaagcgca cgcaggcgcg cgtgctcgat
     7021 gtctggatca acggcctgcg cgtcggtcag tggcaggtca cggcgcaggg cgaagatcgc
     7081 ttccgctatg cgcccgagtg gctcgagtcg gccgaggcgc gcccgctgtc gctctcgctg
     7141 ccgatgccgc tcgacgcagc cgccccggcg ctgagaggcc tgcgggtacg caattacttc
     7201 gacaacctgc tgcccgacag cgagcagatc cgcatgcgcc tgcaggcacg ctttcgcacg
     7261 ccgggaaggg gcgtcttcga actgctgcag gcgatcgggc gcgattgcgt gggcgcggtc
     7321 cagttgctgc ccgaagggca ggggccggaa ggtgtcttcc ggatcgacgc ggagccactc
     7381 gacgaggccg atgtcgagcg cctcctgcgt gcggccgtcg cgccggtgcg cgcctttggc
     7441 gaggtagcga ccgacctgga cgatttccgc atctcgatcg ccggcgcaca ggagaagacc
     7501 gcgctgaccc gccacgcggg gcgctggtgc cgcccgctcg gggcgacgcc gaccacccac
     7561 atcttcaagc tgccgctcgg cctggtcggc aacaggcagg cggacatgcg cacctcggtc
     7621 gagaacgagt ggctgtgcgc gcgcctgctg gcggcgttcg gattgccggt ggcacaatgc
     7681 gagatcgaac actttggcgc gcagaaggtg ctcgtggtcg aacgcttcga tcgtcgcctg
     7741 tccgctacgg gcgattactg gctgcgcctg ccgcaggagg acttctgcca ggccaccgcc
     7801 actccgccgg cgctgaagta cgaggccgat ggcggcccgg gcctgctcga cctcgcccgc
     7861 atcctgcagg gctcggtgcg ccgtgacgat gatctgcgca tcgtgctgaa ggcgcagttg
     7921 ctgttctgga tgctcgctgc ctccgacggg cacgcgaaga acttctccat cttcctgctc
     7981 gcgggcgggc gctaccggct cgcgcccttg tacgacgtgc tgtcggcgtg gccggttgcg
     8041 gggacaggcg agaaccggct cgatccggcg cgcttgcgcc tcgccatggc gctgcgcggg
     8101 cgcaacgctc attaccggct gcgcgacatt cagcgcaggc acttcaacgc gatggcgcac
     8161 cggtgcggcc tcggcgccga catggaggac atcgtcgagg acgtgctcgc gcaactcgac
     8221 ccggtgctcg acaagcttgg cgccgaactg ccggccgggt tccccgagga tgtcttcgcc
     8281 acgatcgccg ctggcatgcg cgccagcgcg cgccgacttc agaaccaaaa aaggacgata
     8341 gacccgacat gacccagacc cccgaccgcg acacccgcca caacgcccgc atggtgcgca
     8401 agaaggacgt cgtcgacgac aggatcgccg ccgcgcaggc cgagcgcggc gtgctgctgg
     8461 tcaacaccgg caacggcaag ggcaagtcca gcgcgggctt cggtctggtg gcgcgcgcgc
     8521 tcggccacgg catgcgggtg ggcgtggtgc agttcatcaa gggccgctcg gacaccggcg
     8581 aggaggcctt cttccgcacc cagccgggcg tcgcctggca cgtgatgggc gagggcttca
     8641 cctgggagac gcaggaccgc gcgcgcgacg tcgcgacggc cgcagctgcc tgggcggtgg
     8701 cacgcgaaat gcttcaaaat cccgaggtcg gcctcgtggt gctggacgag ctcaacatcg
     8761 cgctcaagta ccagtatctc gatgtggacc gggtgatcgc cgacctgcgc gcccggccgc
     8821 cgatgcagca cgtggtggtc accggccgcg gggcgccgcc cgcgctggtc gaggccgccg
     8881 acaccgtcac cgacatgacg ccggtcaagc acgccttcgc cgcgggggtg aaggcgatgc
     8941 ccggcatgga gtggtaagca tggcagttcc cgatcttgcg gttcatcgtc ccggcccgct
     9001 gccgggctgg gtctatctgg tgggcgccgg cccgggcgac ccggagctgt tcacgctgcg
     9061 cggcgcgcgc ctggtggcgg gggcggacgt catcgtctat gacaacctcg tcgcgccgcc
     9121 catcctcgag ctggcgccgg tcgaggccga gcgcatctac gtcggcaaga aggccgccga
     9181 ccactcgctg ccgcaggacg agatcaacct gctgctgctc aagctggcgc gcgagaacaa
     9241 gcgcgtggtg cggctcaagg gcggcgaccc cttcatcttc ggccgcggtg gcgaggagat
     9301 ggagctgctg gtcgaggccg gcatccatgt cgaggtggtg ccgggcgtga ccgcggcggc
     9361 gggcgtctcc gcctacgcgg gcatcccgct cacccatcgc gagcacgcgc agtcggtggt
     9421 gttcgccacc ggcttcctca aggaagggaa gatcgacctc gactggccga tgctcgcgcg
     9481 cccgcagcag accgtggtga tctacatggg gatctcgcgc ctggccgaca tctgtgccca
     9541 gctcgtcgct cacggcctgc cgccgagcac gcccgcgggg gtgatcgagc gcggcaccac
     9601 gcacgcgcag cgcgtggtcg ttgccgacct cgccaccctg gcgcggcgcg tgctggaaga
     9661 aggcgtgcgc ccgccctcgc tgaccgtggt cggcagcgtc gtcgggctgt atcccaagct
     9721 ggcctggttc gagcccgagg accagcccaa ggcctcgccg ctgccgcacg ccggctgtgc
     9781 ggtggtacat gggaagggnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9841 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnncc
     9901 gcctcgggcg gcgggtgcgc gtgttcaagt gcgggccgga cttcctcgac ccgcagatcc
     9961 acgcggtggc gagcggcgcg ccggtacata acgtcgacct cggcatgtgc ggcgaggccg
    10021 acatcgcctg gcggctgcac gccgcggcgc gcgaatccga cctgatcctg gtcgagggcg
    10081 tgatgggact ctacgacggc gcgccctcgg gcgccgacat cgcgcgccgc ttcggcatcc
    10141 cggtgatggc ggtgatcgac gcgcgcgcga tggcgcagac cttcggcgcg gtggcctacg
    10201 ggctggcgca ctaccagccc ggcctgccct tcgccggcgt gctcgccaac cacgtcggca
    10261 gcgcgcgcca cgccgacatg ttgcgcgagt ccttgcctga aggcatgcgc tggttcggcg
    10321 cggtgatgcg cgatgcggag gccgcgctgc ccgagcgcca cctcggcctg ctgcaggcgg
    10381 cggagatcga ggatctcggc gcccggctcg accgcgtcgc cgatcatctg gcgcgcaccg
    10441 gcgcggcgga actgccggcg gtggtggcgt ttcctgccgt ggcggcaccg gcgatcccgc
    10501 ccttgctcgc cggcaagcgc gttgcgatcg cgcgcgacgc cgcctacggc ttcctctacc
    10561 cggccaacat cgacaccctg cgcgcgctcg gcgcagagct cgccttcttc tcgccgctcg
    10621 ccggcgaggg cctgcccacg cagtgcgacg cggtgtggct gccgggcggc tatcccgagc
    10681 tgcacggcgc cgcgctcgcc gccaacgccg ggctgtggac cgatctgcgt gcccatgtgg
    10741 ctgcgggcaa gccggtgctg gccgagtgcg gcggcctgat gagcctgctc gaggccatcg
    10801 tcgacaaggc cggggtggag caaaccttcg cgggcctgtt gcccgggcgt gcggtgatgc
    10861 agtcccgcct cgcggcgctc ggcctgcagg aggtcgattt gccgggcggg cgactgagcg
    10921 ggcacacctt ccattactcg cgcaccgaga caccgctcgc gccctggctg cgcgcgcgtc
    10981 gtccggatgg cggcgagggc gaggcgatct accgctgcgg gccgatcacc gcctcgtacg
    11041 tccatttctg gttcccgtcg aatccggtgg cggccgcggg gcttttcggc gcttgagcgc
    11101 gcgcgccggg cggcgaactg caccggcgca caatcccgcg gccgccttcg cgcctgccgg
    11161 cgctcctaca agaagcctca cgcccgcggt ggcccctgta ggagcggcgg cagccgcgaa
    11221 cnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ntacaagaag cctcacgccc
    11341 gcggtggccc ctgtaggagc ggcggcagcc gcgaacgggc ggtcgagcaa tcgccaccgc
    11401 ggacgaagac gcccaccgcc ttcgcgcccg ccggcgggcc tacgcggcgg gcgttggcgc
    11461 cgccagggcc ttgccggcgg cgtccccgat cgccctggcc agcctcgcca tcaccggcga
    11521 ctgcacctgc caatggtgcc agtacaacac cacttcctcg cgctccggtg ccaggtcgac
    11581 cagttcgccg cgcgcgaggt ggacgcgggc ctggatctcg gggatgaagc cgtaccccag
    11641 gccggcgacc gcgaaggcca tgaagccctc ggaagagggc acgacgtggt gcggatagcg
    11701 ccgcgcatcc agcccgaagt ggtgcagcag gaaggcctcg tgcatgtcgt cgtggcggcc
    11761 gaagacgatc gctggcgcct gcgccagcgc cgccggggtg agcccgtgcg ggaaccagcg
    11821 cgcgcggaag gccggcgagc cggcgcacag gtagggcatg gccccgaggc gcacggcggc
    11881 gcagccgcgc atcgggtcgg cgcgggtgga cacgcagccc agcacctcgc cgtcggcgag
    11941 cagcgcgtgg gtgtggtcct ggtcgtcgac cacgcagtcg agcacgatgc cctcgtcgcg
    12001 gaccacctcg gcgaccgcgc cgatgaacca ggtggcgagc gagtcggcgt tgacgcccac
    12061 cgccaggcgt agcggtccgt ccgcctggcg cggcgacagc gcgcgccgcg cctcggcctc
    12121 catcagccgc agctgcgcca ggtagggcag cagccggcgc ccggccggcg tgggccgcac
    12181 cggcttgctg cgtaccagca gcacctggcc gagctcggcc tcgagcagct tgacgcgttg
    12241 cgacaccgcg gactgggtga gcgagagccg gcgcgccgcg cgctcgaatc cgccctcctg
    12301 cagcaccgcc tcgaaggcga gcagacgttg atcgatcatt agccattcta ctcgaaacga
    12361 aaataaatcg attcttctta acttaaagcg gctccgggcc tatcttcgcg cctgccggcg
    12421 ctcctacacg aagcatcgcg cccgcggcgg cccctgtagg agcggcggca gccgcgaatg
    12481 ggcgctcgag ccatcgacgc tgcggacgaa gacgtacgcc gccttcgcgc ctgccggcgc
    12541 tcctacacga agcatcgcgc ccgcggcggc ccctgtagga gcggcggcag ccgcgaatgg
    12601 gcgctcgagc catcgacgct gcggacgaag acgtacgccg ccttcgcgcc tgccggcgct
    12661 cctacacgaa gcatcacgat cgcgacggcc tttgttggag cggcggcagc cgcgaggacg
    12721 gcggtgcggc ggcgatgggc gttgtcgtgc gcggatgcgc cgcattcgcg cctgccggcg
    12781 ctccaaaatg agccgcgcgg ctccggagtc ccgatgtagg agcggcagca gccgcgaacg
    12841 gcctgcggcc acggaaacgc aaaacaataa aggaacacac catgagcaac gtctatttca
    12901 acggcttcct ccttaccctc ggcctgatca tggcgatcgg cgcgcagaac gcgcacgtgc
    12961 tgcgccaggg cttgcgtggc gagcacgtgc tgctgacgat cggcgtgtcg gcagcgtgcg
    13021 acatcctgtt gatcggcctt ggtatcgccg gtgtcggcag tctcttcgtc gccaatcccg
    13081 acctgatgac ggtggcgcgc tacggtgggg cggccttcct cgtctggtac ggcacgcgcg
    13141 cgctgctctc cgccctgcgc ggcgggcggg cgctggatct cgccgagcac aagcgcatgt
    13201 cgcgcgggca ggcgctgctc gcggcagccg gcttcagcct gctcaacccg cacgcctacc
    13261 tcgacaccgt ggtcctcctc ggttccatcg gcagccagca ggccgaggac ctgcgcccgc
    13321 tcttcgcggc cggcgcgatc agcgcgtcga tcgtgtggtt cctgctgctc ggctatggtg
    13381 cccgcctgct cgcgccgctg ttcgccaagc cagtggcgtg gcgtgtgctg gacgcgttgg
    13441 tggcgctgat gctgtgggcg atcgcggcgt cgttgctgct ggcgtgaggg ggacggagcg
    13501 acggaagacg cgactccggt atggggaagg gcggcgtgtg cacggtctcg agcgtcgtct
    13561 tcgcgcctgc cggcgctcct acgcgggctg ccgggcttcc gccccccccg tgcgagcgtc
    13621 ggcaggcgcg aaaatggcgc ccgctcggcc gcatcgcgct ctccatgcgg agtagcccct
    13681 gctgcaacag gatgttcgcg tggcggagcg ggtgaaccag gcccgctata atcgttgcct
    13741 tcgcgcacct cgtgcgcacg catcaggatc cccgccgtgt ccgaacgcct cgccgtcgcc
    13801 ctccagtacg ccctgcccaa gcgcctcctg acccagcttg ccggaaagct cgccggcctc
    13861 gagggaggca aggtgacgac cgcggtgatc cgctggttcg cgaagcgcta cggcgtgaac
    13921 atggcggagg cggcgaaccc cgatccggcg agctacgcga gcttcaacca gttcttcacc
    13981 cgcccgctgc gtgagggtgc gcggccgatc gcggatgcgg acttcgtctg cccggtcgac
    14041 ggtgcgatca gccagttcgg gccgatcgag ttcgaccagg tcttccaggc caagggccac
    14101 ttctattcca ccactgcgct cgtcggcggc gaccgtgcgc tcgccgcgcg cttcgagagc
    14161 ggcgatttcg ccaccatcta tctgtcgccg cgcgactacc accgcatcca catgccctgc
    14221 gccggcaggc tgactcagat gatctacgtg cccggggagc tgttctcggt gaatccggcc
    14281 acggcgcgcg gcgtgcccgg cctgttcgcg cgcaacgagc gcgtggtgtg cgtgttcgag
    14341 ggcgagttcg gtcccttcgt gatggtgctg gtgggcgcga ccatcgtcgg cagcatggcg
    14401 accgtgtggc acggcgtggt caatccgccg cgccgcccgg acatcgccaa gcgcagctac
    14461 gccgagggcg aggtgatgct ggagcagggc gccgagatgg gccgtttcct gctcggttcg
    14521 acggtggtga tgctgtttcc caaggatacg ctgcgcttcg gctccgactg ggcgccgggc
    14581 gggccggtgc ggatgggcga gccgatggcg cgcgcgaagt cgtccgcgcc ctccgatggt
    14641 gcgccggcgc aggtcgatgc accgtgatgg tggcgggggc cgctgccggc cagcaggacg
    14701 gccggtcacc tttcggtcac gatgctgaaa gaatcctg
//
LOCUS       DAOTIN010000077        14552 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_4973_length_14552_cov_8.809892, whole genome shotgun sequence.
ACCESSION   DAOTIN010000077 DAOTIN010000000
VERSION     DAOTIN010000077.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 14552)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 14552)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14552
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4973_length_14552_cov_8.809892"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            172..2226
                     /locus_tag="P5537_11580"
     CDS             172..2226
                     /locus_tag="P5537_11580"
                     /inference="COORDINATES: protein motif:HMM:NF012801.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HRV78726.1"
                     /translation="MKLKPRLLALALALTPLPALSTPPDPAGITPDADLFELSLEQLM
                     DVVVTSVSKRSQPLSSTAAAVHVISAEDIRRSGAANLPEALRLAPGVHVARFSNNRWS
                     VSIRGFGGRYANKLLVLQDGRSLYSPVYSGVFWEFNDIPLELVERIEVVRGPGASIWG
                     ANAVNGVINIITRNAADARGTQLSASAGTTLRGSLFASHGVALSEGTHLEVHAKSQYV
                     EPSSTTEAGPARDFWRTRQAGFRLDGKSGADTFRLQGSARDSVAGDHFMQRTADIDAA
                     ARDYNSVSELAYLLGRWEHDAGDGTLHSLQAYAEKSRLDILVGSERRSTFDIEYQQQQ
                     RLGARVDFVWGGGWRHTRDEILGDTEGRYVRIDNTRDQADLFSLFAQGEFALVPERWA
                     LILGARADLRDDAKLAFQPNARVLFTPDKTHSLWASLARGVRTASRAEQSVSGTLPAA
                     PLPYPIPMPPLGTATDFVTQLDGNPGFGHEYLDALDLGWRAAWSPALSTEVAAYHYRY
                     DDLRHARPSGNPEPIFARPPYLAQPVQLGTTEQARVSGVEFSAHWRPTDAWDLAASLA
                     LNHMGHSSVDRRSEFSEGTPERIFTLRTGYAISPALQWDAWLRHSSALYTYSFQAGRQ
                     IDPHWTLDMRLGWKASRDLEISIVGQNLLDRRHLEAINEPLPSILTEIERCVYLRADW
                     RL"
     gene            2241..2792
                     /locus_tag="P5537_11585"
     CDS             2241..2792
                     /locus_tag="P5537_11585"
                     /inference="COORDINATES: protein motif:HMM:NF025069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfiR family protein"
                     /protein_id="HRV78727.1"
                     /translation="MTSFRRLFVRALMSGLLGLGLLGAGVAHAADSPEEARLKAVFVF
                     NFIKFTEWAEGSAMRASDRIELCVVGERPLDGQLETLEGRGVRSQTVRVHAWTPTTAG
                     RCDIVFVAAGDGERLRAVLLANARQPLLSVGDEPDFLERGGIIALKLSGGRVRFDINL
                     AAAREAGLRLSSQLLQLADRVVQ"
     gene            2789..5176
                     /locus_tag="P5537_11590"
     CDS             2789..5176
                     /locus_tag="P5537_11590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HRV78728.1"
                     /translation="MKLHDLPIGRKLTLILAATTGAAVLLATLAFSAGGMYRLYRDSE
                     YRLQTLARLTSQNSHGALAFGDDNAARALLAALRAEPNVVRAQLFDAAGRELAAYSAP
                     HEAPERAGLAALAVDLFLPTRLRIVQPVEVGHERLGAVEIQADITSAWLEFGVGLLLA
                     TLAAAVAAAVAVRFGLRLRGRIIAPLLELAEAAGTVVRNQRYDIRVATAGKDEIGRLV
                     EEFNRMLGEIEARDRALQAHRDNLEREVEARTAELRGAKDAAEAASLAKSRFLATMSH
                     EIRTPMNGVLGMTELLLASASDDDQARRARAALQSGENLMAILDDLLDFSKIEAGRME
                     LESIPLDPGRLARELVELAAPIAAGKGLHLCARIDASVPAWVRGDPTRLRQILNNLVG
                     NALKFTVKGEVGLTMRARPGAAPDACVLEIEVRDTGIGVAPEVLPHLFEAFAQADSTT
                     TRRFGGTGLGLAIVRQLVELMDGTIEATSTERVGSTFRVELPLALANAGPATGGAAAA
                     GLRAQHGAARWPGARVLLVEDNPINQTLALEQLRDLGCEPRLACNGAEAVEACAGERF
                     DLVLMDCQMPVMDGYEACRRILAGCGEAPVPIVAMTANAMRGDRERCDAAGMVDFLAK
                     PYRSADLAAVLARWLPESLRVTAPAGSATRAPASAAEQGAGPADRAAADQEVVFDPAA
                     LAELSLQHSGGEAIVAQVLGLFRQEGRRQLDTLREALLGGDIDTATRAAHTLKASAAT
                     LGAMRLSARCRDIEATLRAGSDARVEAWIAEADSAFSAACTEMNGALAQRDNGHA"
     gene            5169..7319
                     /locus_tag="P5537_11595"
     CDS             5169..7319
                     /locus_tag="P5537_11595"
                     /inference="COORDINATES: protein motif:HMM:NF012772.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HRV78729.1"
                     /translation="MPEATRVLIIDDDAVTRLLVGSAMCGAGHEVLENDSGETAMATL
                     EECRPELILLDLEMPGMGGLAFCRWLRTRPACHNLPVLVMTAHDDSTTIQNAFDAGAS
                     DFIAKPLNFNILVHRVRFLLRARDNLRALERSRRNLAEAQGIARLGSWELDRASGIAE
                     CSEALFTVLGRDPQDTERSIAGFVERVHPDDLERVRAAIAASSDGRLPADVIHRYLGD
                     DGRVRWIHLRVKFEHDEQGHARRSYGTVQDITAQRRIEERIDYLLRHDALTGLPNRDH
                     FLQALGTELSRCGEHEQVAVMHIALERYQRISDSLGHEAGDTVLRLAAERVRRCLPGT
                     ELAEIDGRTLLARWSGGELMLMRSGATVTHDASRLARTILDKLRAPFRVGEHELMLGA
                     HIGIAMHPLDGAGAAVLTHAASIASHHARSAGCAEAQFHSAAIQAETRLRMELERDLR
                     RALADDEGGGLTLHYQPKYDHEGHIRGAEALIRWEHPSRGLLPPARFVPLAEEVRLIV
                     PLGKWVIRRACRQLREWLDQGLPEVRIALNLAAPHFVDPDLLPLLIAETAAHGIRSEL
                     IELELTESMLMDDTDYVRDMLRHMHERGFRLAIDDFGMGYSSLSQLSFLPLDTLKIDR
                     VFTQGMLEVPRQAAVVRGIIALAKGLGLSVVAEGVETPAQAAALRAEGCDLMQGFHFD
                     RPLAAADFARRLAGPTPPASPAAAGAAPTTAGRP"
     gene            complement(7357..8406)
                     /locus_tag="P5537_11600"
     CDS             complement(7357..8406)
                     /locus_tag="P5537_11600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Glu/Leu/Phe/Val dehydrogenase dimerization
                     domain-containing protein"
                     /protein_id="HRV78730.1"
                     /translation="MAVFSLSDFADHEQVVFVSDDKSGLKAIIAVHNSNLGPALGGCR
                     MWPYASEEEAVRDVLRLSRGMTYKSAMARLKLGGGKSVIIGNPRTDKTPALLAAFARA
                     LEQLNGRYIAAEDSGTSVADMKFMTQFTQHVAGIHDKPSDEGTRSGDPSPATAYGTFI
                     GIQAAVKERLGRDSLDGLRVAVQGVGNVGYDLARQLKEAGAQLWVTDIHREPLVQAGR
                     ELGATVVAPDEIFGLDVDVFAPCALGAVLNDSTIPQLKASIVAGAANNQLAEARHGVE
                     LMKRGILYAPDYVINAGGIIDVYHERIGFERAALIRHIEGIRDNLMEVFERAREEERP
                     TAEVADAIAEERFRR"
     assembly_gap    8623..8722
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(9075..12668)
                     /locus_tag="P5537_11605"
     CDS             complement(9075..12668)
                     /locus_tag="P5537_11605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase family
                     protein"
                     /protein_id="HRV78731.1"
                     /translation="MSNIAPNVSLDDKYTLKTGRAWMTGIQALVRLPMMQKLRDEAAG
                     LNTAGFVTGYRGSPLGSVDQEFWKAKRFLEPMNIRFQPGLNEDLAATSVWGTQQLGLD
                     PNAKVDGVFSIWYGKGPGVDRTCDVFRHANAAGTSQHGGVLVIAGDDHAAKSSTLPHQ
                     TEHVFKALMMPVLAPAGIQEYLEYGLHGFAMSRYSGCWVAFKALTDTVETSSSVDIDP
                     FRVQTRIPSAEEFPLPLDGLNLRWPDPPLVQEERLLHHKLYAALAYGRKNGLDRMVID
                     PPQARLGILTSGKSYLDVRQALDDLGIDEATAAAIGLRLYKVGMVWPLDAEGVRRFAD
                     GLDEILVIEEKRQFLEYQLKEELYNWKDEVRPRVIGKFDEKGEWSLPHADWLLPAAGE
                     LTPAMIARAIAGRIARFHTSDRIKARLAFIEAKEAALAKPRLSIQRVPHYCSGCPHNT
                     STKVPQGSRAIAGIGCHYMATWLSPEHTQTFCQMGGEGVPWIGQAPFTDTPHVFANLG
                     DGTYMHSGILAIRAAVAAKVNITYKVLYNDAVAMTGGQPHDGTLSVPIIARQLLAEGV
                     GTVVVVNDGTPRAYGPADLPHGVAVRHRDELDAVQRELRTAPAVTAIIYDQTCAAEKR
                     RRRKRGKFPDPAKRVVINDLVCEGCGDCSDKSNCMSVGAVETEFGRKRFIDQSSCNKD
                     YSCVKGFCPSFVTVEGGALRKGKASGAVAPGGLADALPEPQLPDTAAPWGILITGVGG
                     TGVVTIGALLGMAAHLEGKGISVLDMAGLAQKGGAVWSHVRIADRQAQLHAARVAAGE
                     ADAVIGCDLVVAASDESLAKMQHGRTRVLINRDQTNTSEFVRGFAAQARSGDVLANPD
                     PQFPAAAMEAQIVDAVGADQAEFLDATALATELLGDSIATNLFMLGFAWQRGLVPLSR
                     QAIERAIEINGTAIEANKAAFLWGRRAAVDLRAVREAARPRFGTPAHHRLSTSVDELI
                     ARRKAQLTDYQDAAYAERYTRLVERVRAAEARVAPGIQLLTEAVARGYHKLLAYKDEY
                     EVARLYTDSDFLKRVEEQFEGDYKLVFHLAPPMLADKDPQTGELKKKAYGPWMLKAMR
                     VLAKFRHLRGSKLDPFARSHDRQLDRELIADYERLVDEIVVNLDRANHEAAIELAALP
                     EHIRGYGHVRERYLAGARKRQAALLEDFRQRRAPSTPVVTRARRTIAIIPG"
     gene            13141..14481
                     /locus_tag="P5537_11610"
     CDS             13141..14481
                     /locus_tag="P5537_11610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004381806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HRV78732.1"
                     /translation="MAKHAHSQWSSRMGFVLAATGSAVGLGNIWKFPYMVGQSGGAAF
                     VLVYLACIAFIGVPILVAEWMIGRRGQKNPINTMAQLARQNGHSTNWAVVGAVGVLAA
                     FLILSFYSVIGGWALAYMRDAATGAFIGLDKAAIGGAFEGFLARPAELLTWHSIFMLL
                     TVVVVALGVSAGLERGTKLMMPALGLILIVLVGYAMTTGSFGEGLAYLFNPDWSKLDG
                     KVLLAALGHAFFTLSLGMGIMMAYGSYLGQEVNLLRTARTVVIMDTVFALCAGMAIFP
                     IVFANGLDPAAGPGLVFVTLPLAFGHMGGGLVIGALFFLLLTFAALTSSISLLEPVVE
                     LIEERTPLGRVAATMIAGITIWALGIAALLSFNVWGDVKLFGMNIFDLLDYATSKFML
                     PLAGLGAIVFAAWKLDQQGVKAELGLGDGAFGLWTLLSRYVAPVGVLFVFWSNL"
BASE COUNT         2079 a         5155 c         5057 g         2161 t
ORIGIN      
        1 ggattatttc cgcgatcgcc cggggcggtt ctcgcgcgaa tgcggccggg ctttcgttcg
       61 ccgacgtgcg acgcatcacg cgaatatttg ccacgcgcat atatactctc ggcctcgaaa
      121 aaacacggtg acggcagggc tgcgccgcgc cgacccacaa gccgccaagc catgaagctc
      181 aagccccgcc tgctcgccct cgctctggca ctcaccccct tgccggcgct ctcgacccca
      241 ccggatccgg ccggcatcac gcccgacgcc gacctcttcg agctcagcct cgagcagctc
      301 atggacgtgg tggtgacctc ggtttcgaag cgctcgcagc cgctgtcgag cacggcagcc
      361 gcggtccatg tgatcagcgc cgaggacatc cgccgcagcg gcgccgccaa cctgcccgaa
      421 gcgctgcgcc tggcgccggg cgtgcatgtc gcgcgctttt ccaacaaccg ctggagcgtg
      481 tccatccgcg gtttcggcgg gcgctacgcg aacaagctgc tggtgctgca ggacgggcgc
      541 agcctgtact cgcccgtgta ttcgggcgtg ttctgggagt tcaacgacat cccgctcgag
      601 ctcgtcgagc gcatcgaggt ggtgcgtggc cccggcgcgt cgatctgggg ggccaacgcg
      661 gtcaatggcg tgatcaacat catcacccgc aacgccgccg acgcccgcgg cacgcagctg
      721 tccgcgagcg ccggcaccac gctgcgcggc agcctgttcg ccagccacgg cgtggccttg
      781 tcggaaggca cccacctcga ggtccacgcc aagtcgcaat acgtcgaacc ctcatcgacc
      841 accgaggccg gcccggcgcg cgacttctgg cgcacccgcc aggccggctt ccggctcgac
      901 ggcaagtcgg gagccgacac cttccgcctg cagggcagcg cgcgcgacag cgtcgcgggc
      961 gaccacttca tgcagcgcac cgcggacatc gacgcggcgg cgcgcgacta caacagcgtc
     1021 agcgaactcg cctacctgct cggccgctgg gagcacgacg ccggcgacgg cacgctccac
     1081 agcctgcagg cctacgcgga gaagtcccgt ctcgacatcc tcgtcggcag cgagcgccgc
     1141 agcaccttcg acatcgagta ccagcaacag caacgcctcg gcgcgcgcgt cgacttcgtc
     1201 tggggcggcg gctggcggca cacgcgcgac gagatcctcg gcgacaccga agggcgttac
     1261 gtccgcatcg acaacacccg cgaccaggcc gacctcttca gcctgttcgc gcagggcgag
     1321 ttcgccctcg tccccgagcg ctgggcgctg atcctgggcg cacgcgccga cctgcgcgac
     1381 gatgccaagc tcgccttcca gcccaacgcg cgcgtgctgt tcacgcccga caagacgcac
     1441 agcctgtggg cctcgttggc gcgcggtgta cgcacggcct cgcgcgcgga gcagtcggtg
     1501 tcggggacgc tgccggccgc gcccttgccg tacccgatcc ccatgccgcc gctcggcacg
     1561 gccaccgatt tcgtgaccca gctcgacggc aaccccggtt tcggccacga gtacctcgat
     1621 gcgctcgacc ttggctggcg cgcggcgtgg tcgccggcgc tcagcaccga ggtcgcggcg
     1681 tatcactacc gctacgacga cctgcggcac gcgaggccaa gcggcaaccc ggagccgatc
     1741 ttcgcgcgcc caccatacct cgcgcagcct gtccagctcg gcaccaccga acaggcccgt
     1801 gtcagcggcg tcgagttcag cgcccactgg cgccccaccg atgcctggga cctcgccgcc
     1861 agcctcgccc tcaaccacat gggccacagc agcgtcgacc ggcgcagcga gttctccgag
     1921 ggcacgcccg agcgcatctt caccctgcgc accgggtacg cgatctcgcc cgcgctgcag
     1981 tgggacgcct ggctgcggca ctcgagcgcg ctgtacacct actccttcca ggccggccgg
     2041 cagatcgacc cgcactggac gctggacatg cgcctgggct ggaaagccag ccgcgacctg
     2101 gagatctcca tcgtcggcca gaacctgctc gaccgccgac acctcgaggc gatcaacgag
     2161 ccgctgccct cgatcctcac cgagatcgag cgctgcgttt acctgagggc ggactggcgt
     2221 ctctgagcgg tcgcgcagcg atgacctcct tccgtcgcct cttcgtgcgc gcgctcatgt
     2281 cggggctgct cggcctcggc ctgctcggcg cgggcgtcgc gcacgccgcc gactcgcccg
     2341 aagaggcgcg gctgaaggcc gtcttcgtgt tcaacttcat caagttcacc gagtgggccg
     2401 agggcagcgc gatgcgcgcc agcgaccgca tcgagctgtg cgtggtcggc gagcgtccgc
     2461 tcgatggcca gctcgagacg ctcgaggggc gcggcgtgcg cagccagacc gtccgcgtac
     2521 atgcctggac cccgaccacg gcggggcgct gcgacatcgt cttcgtcgcc gcgggagatg
     2581 gcgagcgcct tcgcgccgtg ctgctggcca acgcccgcca gcccctgctg agcgtgggag
     2641 acgagcccga cttcctcgaa cgtggcggca tcatcgcgct caagctcagc ggcgggcggg
     2701 tacgcttcga catcaacctt gcggccgcgc gcgaggctgg cctgcgcctg agcagccagc
     2761 tcctgcagct cgccgaccga gtcgtgcaat gaagctgcac gaccttccga tcggccgcaa
     2821 gctcacgctg attctcgcgg cgacgaccgg agccgcggtc ctgctcgcga ccctggcctt
     2881 ttccgccggc ggcatgtacc gcctctatcg cgacagcgag taccgcctgc agaccctcgc
     2941 ccgcctcacc agccagaaca gccatggcgc gctcgccttc ggcgacgaca atgcggcgcg
     3001 cgcgctgctg gccgcgctgc gcgccgaacc caatgtggtt cgcgcgcagc tcttcgacgc
     3061 cgccggacgc gagctcgccg catacagcgc gccacacgag gcgcccgagc gcgccgggct
     3121 cgccgcgctt gcggtggacc tcttcctgcc gacccggctg cgcatcgtgc agccggtgga
     3181 ggtcggccac gagcgcctgg gggcggtcga gatccaggcc gacatcacct cggcctggct
     3241 ggagttcggc gtgggcctgc tgctcgccac cctggccgct gcggtcgccg ccgccgtggc
     3301 ggtgcgcttc ggactgcgcc tgcgcggccg catcatcgcg ccgctgctgg agctcgccga
     3361 ggccgcgggg acggtggtgc gcaaccagcg ctacgacatc cgcgtcgcca ccgcgggcaa
     3421 ggacgagatc ggccgcctcg tggaggagtt caaccgcatg ctgggcgaga tcgaggcacg
     3481 agaccgcgcg ctgcaggccc accgcgacaa cctggagcgc gaggtcgagg cgcgcaccgc
     3541 cgagctgcgc ggcgccaagg atgccgccga ggccgccagc ctcgccaagt cgcgcttcct
     3601 cgccaccatg agccacgaga tccgcacgcc gatgaacggc gtgctcggca tgaccgagct
     3661 gttgctggcc tcggcaagcg acgacgacca ggcgcgcagg gcacgcgccg cgctgcagtc
     3721 gggcgagaac ctgatggcca tcctcgacga cctgctcgat ttctccaaga tcgaggccgg
     3781 tcgcatggag ctcgaatcca tcccgctcga ccccggccgc ctcgcccgcg agctcgtcga
     3841 gctcgccgcc ccgatcgccg cgggcaaggg cctgcatctg tgcgcgcgga tcgacgcgag
     3901 cgtgccggcc tgggtgaggg gcgaccccac acgcctgcgc cagatcctga acaacctcgt
     3961 cggcaatgcg ctcaaattca cggtcaaagg cgaggtggga ctgacgatgc gcgcccgccc
     4021 aggcgccgcc cccgacgcct gcgtgctcga gatcgaggtt cgcgacaccg gcatcggcgt
     4081 cgcacccgag gtcctgcccc acctgttcga agccttcgcc caggccgaca gcaccacgac
     4141 ccgtcgcttc ggcggcaccg ggctcgggct ggcgatcgtg cgccagctgg tcgagctcat
     4201 ggacgggacg atcgaggcca cgagcacgga acgagtcgga tcgaccttcc gtgtcgaact
     4261 cccgctggcg ctcgcgaacg cgggccctgc cacagggggc gcagcagcgg ccgggctgcg
     4321 ggcgcaacac ggggccgcgc gctggccggg cgcgcgcgtg ctgctggtcg aggacaatcc
     4381 gatcaaccag acgctggcgc tcgagcagtt gcgcgacctg ggctgcgaac cacggctcgc
     4441 ctgcaacggt gccgaggcgg tcgaggcctg tgccggcgag cgcttcgacc tggtgctgat
     4501 ggactgccag atgccggtga tggacggcta cgaggcctgc cggcgcatcc tcgcagggtg
     4561 cggcgaggcg cccgtgccaa tcgtggcgat gaccgccaac gccatgcgtg gggaccgcga
     4621 gcgctgcgac gccgcgggga tggtggattt cctcgccaag ccctaccgca gcgcggatct
     4681 cgccgcggtg ctggcgcgct ggctgccgga gtcgctgcgg gtgacggcgc cagccggctc
     4741 cgcgacccgc gcgccggcga gcgccgcgga gcagggagca ggcccggccg acagggccgc
     4801 agcagaccag gaggtcgtgt tcgaccccgc ggcgctcgcc gagctgtcgc tgcagcattc
     4861 cggaggcgag gcgatcgtgg cgcaggtgct cgggctgttt cgccaggaag gccgcaggca
     4921 gctcgacacc ctgcgagagg ccttgctggg cggggacatc gacaccgcga cgcgcgccgc
     4981 acatacgctc aaggcgagcg ccgcgacgct cggggcgatg cgcctgtccg cgcgctgccg
     5041 cgacatcgag gccacgctgc gggccggcag cgacgcacgg gtcgaggcct ggatcgccga
     5101 ggccgacagc gccttctcgg ccgcctgcac ggaaatgaat ggcgcattgg cgcagaggga
     5161 caacggacat gcctgaagcg acacgcgtgc tgatcatcga cgacgacgcc gtcacccgcc
     5221 tgctggtggg cagcgcgatg tgcggcgccg gccacgaggt gctggagaac gacagcggcg
     5281 agaccgcgat ggccaccctc gaagaatgcc ggccggagtt gatcctgctc gacctcgaga
     5341 tgcccggcat gggcggcctg gccttctgcc gctggctgcg cacccggccc gcctgccaca
     5401 acctgcccgt gctggtgatg accgcgcacg acgacagcac gaccatccag aacgccttcg
     5461 acgccggcgc ctcggacttc atcgccaaac cgctcaactt caacatcctc gtgcatcggg
     5521 tgcgcttcct gctgcgcgcc cgcgacaacc tgcgcgccct cgagcgcagc cggcgcaatc
     5581 tcgccgaggc gcagggcatc gcccggctgg gcagctggga gctggaccgc gcctcgggca
     5641 tcgccgagtg ctcggaggcg ctgttcaccg tgctcggtcg cgacccgcag gacaccgagc
     5701 gctcgatcgc aggcttcgtc gagcgggtgc atccggacga tctcgaacgc gtgcgcgcgg
     5761 cgatcgcggc ctccagtgac gggcgcctgc cggccgacgt catccaccgc tacctcggcg
     5821 acgacggccg cgtccgctgg atccacctgc gggtgaagtt cgaacacgac gagcagggcc
     5881 acgccaggcg atcctacggc acggtgcagg acatcaccgc gcagcgccgc atcgaggagc
     5941 gcatcgacta cctcctgcgc cacgacgccc tcaccggcct gcccaaccgc gaccacttcc
     6001 tgcaggcgct cggcacggag ctctcacgct gtggcgaaca tgaacaggtc gccgtgatgc
     6061 atatcgcgct cgaacgctac cagcgcatca gcgacagcct cggccacgag gcgggcgaca
     6121 cggtgctgcg cctggccgcc gagcgggtcc ggcgctgcct gcccggcacc gagctggcgg
     6181 agatcgacgg gcggacgctg ctggcgcgct ggagcggcgg cgagctgatg ctgatgcgca
     6241 gcggcgccac tgtgacccac gacgcctcgc gcctggcgcg gacgatcctc gacaagctgc
     6301 gcgcgccctt ccgcgtcggc gagcacgagc tcatgctcgg ggcgcacatc ggcatcgcaa
     6361 tgcatccgct cgacggcgcg ggcgcggccg tcctcaccca cgccgccagc atcgccagcc
     6421 atcatgcgcg cagcgccgga tgcgccgaag cgcagttcca ctccgccgcg atccaggccg
     6481 aaacccgcct gcgcatggag ctcgagcgcg acctgcggcg cgcgctcgcc gacgacgagg
     6541 gcggcgggct gaccctgcat taccagccca agtacgacca cgaaggccac atccgcggcg
     6601 cggaggcgct gatccgctgg gagcacccca gccgcggcct gctgccgccg gcgcgcttcg
     6661 tcccgctcgc ggaggaagtc cgcctgatcg tgccgctcgg caagtgggtg atccggcgcg
     6721 cctgtcgcca gctgcgcgag tggctggacc agggcttgcc cgaggtgcgc atcgcgctca
     6781 acctcgccgc gccgcacttc gtcgatcccg acctgctccc cctgctgatt gccgagaccg
     6841 cggcccacgg catccgcagc gagctgatcg agctcgagct caccgagagc atgctgatgg
     6901 acgacactga ctacgtccgc gacatgctgc gccacatgca cgagcgtggc ttccgcctcg
     6961 ccatcgacga cttcggcatg ggctactcgt cgctgagcca gctgagcttc ctgccgctcg
     7021 acacgctcaa gatcgatcgc gtgttcaccc agggcatgct ggaggtgccg cgccaggccg
     7081 cggtggtgcg cggcatcatc gcgctggcca agggactggg gctgagcgtg gtcgccgagg
     7141 gggtggagac gcccgcccag gccgcggccc tgcgcgccga aggctgcgac ctcatgcagg
     7201 gcttccattt cgaccgcccg ctggcggcgg cagacttcgc ccgccgcctg gccggcccga
     7261 cgccgcccgc gtccccggcc gcagccggcg ccgccccgac cacggccggc aggccgtagc
     7321 cgcggcgcgc ggccccgtcc ccccggcgac cggagctcaa cggcggaagc gctcctcggc
     7381 gatcgcgtcg gcgacctcgg cggtggggcg ctcttcctcg cgagcgcgct cgaagacttc
     7441 catcaggttg tcgcggatgc cttcgatgtg gcggatcagc gcggcacgct cgaagccgat
     7501 gcgctcgtga tagacgtcga tgatgccgcc ggcgttgatg acgtagtcgg gcgcatagag
     7561 gatgccgcgc ttcatcagct cgacgccgtg gcgtgcttcg gcgagctggt tgttggccgc
     7621 gccggcgacg atgctggcct tgagctgcgg gatggtgctg tcgttgagga cggcaccgag
     7681 cgcgcagggg gcgaacacat cgacgtcgag gccgaagatc tcgtcgggtg cgaccacggt
     7741 ggcgccgagc tcgcggccgg cctgcaccag cggctcgcgg tggatgtcgg tcacccacag
     7801 ttgcgcaccg gcttccttga gctggcgggc gaggtcgtag ccgacgttgc ccacgccctg
     7861 caccgccacg cgcaggccgt cgagcgagtc gcggccgagg cgctccttca ccgcggcctg
     7921 gatgccgatg aaggtgccgt aggcggtagc gggcgacggg tcgccgctac gcgtgccttc
     7981 gtccgaaggc ttgtcgtgga tgccggcgac atgctgcgtg aactgcgtca tgaacttcat
     8041 gtcagccacg ctggtgccgg agtcctcggc ggcgatgtag cgcccgttca gctgctcgag
     8101 cgcacgcgcg aaggcggcga gcagcgcggg ggtcttgtcg gtacgcgggt tgccgatgat
     8161 caccgacttg ccgccgccga gcttgagccg cgccatcgcc gacttgtagg tcatgccgcg
     8221 cgacaggcgc agcacgtcgc gcaccgcctc ctcctcgctg gcgtagggcc acatgcggca
     8281 gccgccgagc gcggggccga ggttggaatt gtggacggcg atgatcgcct tcagtccgct
     8341 cttgtcatcg ctgacgaaga ccacctgctc gtggtcggcg aagtcgctca gggaaaatac
     8401 ggccatgctg tgtctccttc cttatgggaa cgtgaggggg tgtcgccgcg ccggcgccgc
     8461 ggttggcagc gtcggcggac ggattgggta caggtgctac cgggaacggc agcctcgaac
     8521 ggtgatacgg tgcgcaaccg cccgcaaggc tcgcggctgc cgccgctcct gcaggccgcc
     8581 acgcggcgat ggccttctgc aggagcgccg gaaggcgcga acnnnnnnnn nnnnnnnnnn
     8641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8701 nnnnnnnnnn nnnnnnnnnn nncctgcagg ccgccacgcg gcgatggcct tctgcaggag
     8761 cgccggaagg cgcgaacacg gcgcggaagc ggagaaatcg gggacggacc gcgatttccg
     8821 aaccgcccgc aaagctcgcg gctgccgccg ctcctgcagg ccgccacgcg acgatggccc
     8881 tctgtaggag cgccggaagg cgcgaacacg gcgcggaagc ggagaaatcg gggacggacc
     8941 gcgatttccg aaccgcccgc aaagctcgcg gctgccgccg ctcctacagg ccgccacgcg
     9001 gcgatggcct tctgtaggag cgccggaagg cgcgaacatg gcgcggaagc aggggaaagc
     9061 ccccttttcc cgaatcagcc cgggatgatc gcgatcgtcc tgcgcgccct ggtcaccacg
     9121 ggcgtgctcg gcgcgcggcg ctggcggaag tcctcgagca gcgcggcctg gcgcttgcgc
     9181 gcgccggcga ggtaacgctc gcgcacgtgg ccgtagccgc ggatgtgctc gggtagggct
     9241 gccagctcga tcgccgcctc gtggttggcg cgatccagat tgacgacgat ctcgtcgacc
     9301 aggcgctcgt agtcggcgat cagctcgcgg tcgagctggc ggtcgtggct gcgtgcaaac
     9361 ggatcgagct tcgagccgcg caggtggcgg aacttcgcca gcacgcgcat cgccttcagc
     9421 atccaggggc cataggcctt cttcttcagc tcgccggtct gcgggtcctt gtcggccagc
     9481 atcggcggcg cgaggtggaa gacgagcttg tagtcgccct cgaactgctc ctcgacgcgc
     9541 ttcaggaagt cactgtcggt gtacaggcgc gcgacctcgt actcgtcctt gtaggcgagc
     9601 agcttgtgat agccgcgcgc gaccgcctcg gtcagcagct ggatgccggg ggcgaccctg
     9661 gcctcggcgg cgcgcacgcg ctcgacgagg cgcgtgtagc gctcggcgta ggcggcgtcc
     9721 tggtagtcgg tcagctgcgc cttgcggcgc gcgatgagct catcgacgct ggtcgacagg
     9781 cggtggtgcg cgggcgtgcc gaagcggggc ctggcagcct cgcgcaccgc acgcaggtcg
     9841 accgcggcgc ggcggcccca caggaaggcg gccttgttgg cctcgatcgc cgtgccgttg
     9901 atctcgatcg cgcgctcgat cgcctgccgc gacagcggca ccaggccgcg ctgccaggcg
     9961 aagccgagca tgaacaggtt ggtggcgatc gagtcgccga gcagctcggt ggcgagcgcg
    10021 gtggcgtcga ggaattcggc ctgatcggcg ccgacggcgt cgacgatctg cgcctccatc
    10081 gccgcggccg ggaactgcgg gtcggggttg gcgagcacgt cgccgctgcg cgcctgggcg
    10141 gcgaagccgc gcacgaactc gctggtgttg gtctggtcgc ggttgatgag gacgcgggtg
    10201 cggccgtgct gcatcttggc gagcgactcg tcgctggccg ccaccaccag gtcgcagccg
    10261 atcaccgcat cggcctcgcc ggcggcgacg cgggcggcgt ggagctgcgc ctggcggtcg
    10321 gcgatgcgca cgtgcgacca caccgcgccg cccttctgcg ccagccccgc catgtcgagc
    10381 accgagatgc ccttgccctc caggtgcgcg gccatgccga gcagcgcgcc gatggtgacc
    10441 acgccggtgc cgccgacgcc ggtgatgagg atgccccagg gcgcggcggt atccggcagc
    10501 tgcggctcgg gcagcgcgtc ggcgaggcct ccgggcgcga cggcgccact cgccttgccc
    10561 ttgcgcagcg ccccgccctc gacggtgacg aagctcgggc agaagccctt cacgcaggaa
    10621 tagtccttgt tgcacgagct ctggtcgatg aagcgcttgc ggccgaactc ggtctccacc
    10681 gcgcccaccg acatgcagtt cgacttgtcg ctgcagtcgc cgcagccctc gcacaccagg
    10741 tcgttgatca ccacgcgctt ggccgggtcg gggaacttgc cgcgcttgcg gcggcggcgc
    10801 ttctcagcgg cgcaggtctg gtcgtagatg atggcggtca ccgccggcgc cgtgcgcagc
    10861 tcgcgctgca ccgcgtcgag ctcgtcgcgg tggcgcaccg ccacgccgtg cggcaggtcg
    10921 gcgggaccgt aggcgcgcgg cgtgccgtcg ttgaccacga ccaccgtgcc cacgccctcg
    10981 gcgagcagct gacgggcgat gatcggcacc gacagcgtgc cgtcgtgcgg ctggccgccg
    11041 gtcatcgcca cggcgtcgtt gtagagcacc ttgtaggtga tgttgacctt cgccgccacc
    11101 gcggcgcgga tggcgaggat gcccgagtgc atgtaggtgc cgtcaccgag gttggcgaac
    11161 acgtgcgggg tatcggtgaa gggcgcctgg ccgatccagg gtacgccctc cccgcccatc
    11221 tggcagaagg tctgggtgtg ctcgggggac agccaggtcg ccatgtagtg gcagccgatg
    11281 ccggcgatcg cgcgcgagcc ctgcggcacc ttggtcgagg tgttgtgcgg acagccggaa
    11341 cagtaatgcg gcacgcgctg gatggacagt cgcggttttg cgagtgcggc ctccttggcc
    11401 tcgatgaagg cgagccgcgc cttgatgcgg tcggaggtgt ggaagcgcgc gatgcggccg
    11461 gcgatcgcgc gcgcgatcat cgccggggtg agctcgccgg cggcgggcag cagccagtcg
    11521 gcgtgcggca ggctccactc gcccttctcg tcgaacttgc cgatgacgcg cgggcgcacc
    11581 tcgtccttcc agttgtagag ctcttccttc agctggtact cgaggaactg gcgcttctcc
    11641 tcgatcacca ggatctcgtc gaggccgtct gcgaagcggc gcacaccctc ggcgtcgagc
    11701 ggccacacca tgccgacctt gtacaggcgc aggccgatcg ccgcggcggt ggcctcgtcg
    11761 atgccgaggt cgtcgagcgc ctggcgcacg tcgaggtagc tcttgccgct ggtgaggatg
    11821 cccaggcggg cctgcggcgg gtcgatgacc atgcggtcca ggccgttctt gcggccgtag
    11881 gcgagcgcgg cgtagagctt gtggtggagc aggcgctcct cctgcaccag cggcgggtcg
    11941 ggccagcgca ggttgaggcc gtcgagcggc agcgggaact cttccgcgct cgggatccgc
    12001 gtctgcacgc ggaaggggtc gatgtcgacc gaggacgagg tctcgaccgt gtcggtcagc
    12061 gccttgaacg ccacccagca gcccgagtag cgcgacatcg cgaagccgtg caggccgtac
    12121 tccaggtact cctggatgcc cgcgggggcg agcaccggca tcatcagcgc cttgaacacg
    12181 tgctcggtct ggtgcggcag ggtcgaggac ttggcggcgt ggtcgtcgcc ggcgatcacc
    12241 agcacgccgc cgtgctgcga ggtgccggcg gcgttggcgt ggcggaagac gtcgcaggtc
    12301 cggtccacgc cggggccctt gccgtaccag atcgagaaca cgccatcgac cttggcattg
    12361 ggatcgaggc cgagctgctg cgtgccccac accgaggtcg cggcgaggtc ctcgttgagg
    12421 ccgggctgga agcggatgtt catcggctcg aggaagcgct tcgccttcca gaactcctgg
    12481 tctacgctgc cgagcggcga gccgcggtag ccggtgacga agccggcggt gttcaggccg
    12541 gcagcctcgt cgcgcagctt ctgcatcatc ggcaggcgta ccagggcctg gatgccggtc
    12601 atccaggcgc ggccggtctt gagggtgtac ttgtcgtcga ggctgacgtt gggtgcgatg
    12661 ttcgacatgg tggcgtgaac cgccgccggt cggcaggccg gcgcgtctgg cgcgggctgc
    12721 cggcgggtcg gcgtggtctc ctctgcgggt ggatcggtac gccatcgcgg ccggttgggc
    12781 ccgtggcgct tgcggaagca catgctaggg cgatcggcgg aaaagatttt tcgcaatcgg
    12841 gggtgcagac ctcgatataa gaaaaatttt ttcgcttatc gaatcgtacg atgcgcgcca
    12901 gtcggaccga accgtccggc gaccacaaga tgggtcggca cggatccgcg aacgtggcgg
    12961 cgcaggcatc ccgcttggga ggcgggcgcc ggacgtttag aatccgcgcc ttttccctcc
    13021 gcgccacaag cgcgtcaaaa ctcgaggaga cttgcatgaa tcgaaccgcc gccacccgcg
    13081 gcgccgccac tgcgcggccg cacgccaccg tcgcccccac ccgccgcgag gaccgctgac
    13141 atggccaagc acgcacacag ccaatggtcg tcgcggatgg gcttcgtgct cgccgccacc
    13201 ggctccgccg tcggcctcgg caacatctgg aagtttccct acatggtcgg ccagagcggc
    13261 ggcgccgcct tcgtgctggt ctatctcgcc tgcatcgcct tcatcggcgt accgatcctg
    13321 gtcgcggagt ggatgatcgg ccggcgcggg cagaagaacc cgatcaacac catggcccag
    13381 ctcgcgcgcc agaacggcca cagcaccaac tgggcggtgg tcggcgcggt cggcgtgctc
    13441 gccgccttcc tgatcctgtc cttctactcc gtgatcggcg gctgggcgct ggcctacatg
    13501 cgcgacgccg ccaccggcgc cttcatcggc ctggacaagg ccgcgatcgg cggcgccttc
    13561 gagggcttcc tcgcccgccc ggccgagctg ctgacctggc actcgatctt catgctgctc
    13621 accgtggtcg tcgtggccct cggcgtatcc gccggcctgg agcgcggcac caagctgatg
    13681 atgcctgcgc tcgggctgat cctgatcgtg ctggtcggct atgcgatgac caccggcagc
    13741 ttcggcgagg gcctcgccta cctgttcaac ccggactgga gcaagctcga cggcaaggtg
    13801 ctgctcgcgg cgctcggcca cgccttcttc accctgtcgc tgggcatggg catcatgatg
    13861 gcctacggct cctacctcgg ccaggaggtg aacctgcttc gcaccgcgcg cacggtggtg
    13921 atcatggaca cggtgttcgc gctgtgcgcg ggcatggcga tcttcccgat cgtgttcgcc
    13981 aacggcctcg accccgcggc cggccccggc ctggtgttcg tcaccctgcc gctggccttc
    14041 ggccacatgg gtggcggcct ggtgatcggc gcgctgttct tcctgctgct gaccttcgcc
    14101 gcgctgacct cgtcgatctc gctgctcgag ccggtggtgg agctgatcga ggagcgcacc
    14161 ccgctcggcc gcgtggccgc cacgatgatc gccggcatca ccatctgggc gctgggcatc
    14221 gccgcgctgc tgtccttcaa cgtatggggc gacgtcaagc tgttcggcat gaacatcttc
    14281 gacctgctcg actacgcgac gagcaagttc atgctgccgc tcgccggcct gggcgcgatc
    14341 gtgttcgcgg catggaagct ggaccagcag ggcgtgaagg cggagctggg gcttggcgac
    14401 ggcgccttcg gactgtggac gctgctgtcg cgctacgtcg cgccggtggg cgtgctgttc
    14461 gtgttctgga gcaacctgta agcattgcag cgccgccttc gcgcctgccg gcgctcctgc
    14521 aggaaccgcc gcggccccgg gccatgtagg ag
//
LOCUS       DAOTIN010000078        14494 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_4994_length_14494_cov_9.258328, whole genome shotgun sequence.
ACCESSION   DAOTIN010000078 DAOTIN010000000
VERSION     DAOTIN010000078.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 14494)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 14494)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14494
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4994_length_14494_cov_9.258328"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..2345
                     /gene="carB"
                     /locus_tag="P5537_11615"
     CDS             <1..2345
                     /gene="carB"
                     /locus_tag="P5537_11615"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002928135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006807 - nitrogen compound metabolic
                     process [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HRV78733.1"
                     /translation="VIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDELRNDIT
                     GGATPASFEPSIDYVVTKIPRFAFEKFPQANDRLTTQMKSVGEVMAMGRSFQESFQKA
                     LRGLEVGVYGLDEVEADREDLEHELASPGAQRIWYVGQAFREGMSLEQVFNLSKIDPW
                     FLAQIEDIVLSEKALAGRSLKALQAAELRELKKKGFSDRRLAKLLNTDETAVRLHRHT
                     VGVRPVFKRVDTCAAEFATSTAYLYSSYEDECEAMPTERKKIMVLGGGPNRIGQGIEF
                     DYCCVHAALALREDGYETIMVNCNPETVSTDYDTSDRLYFEPITLEDLLEIVHIEKPV
                     GVIVQFGGQTPLKRAQALEENGVPIIGTSPDMIDAAEDRERFQKLLNDLGLKQPPNRT
                     ARTPEQAVRLAAEIGYPLVVRPSYVLGGRAMEIVHEQKDLERYMREAVKVSNESPVLL
                     DRFLNDATEVDVDALSDGKQVMIGGIMEHIEQAGVHSGDSACSLPPYTLSAKLQDELR
                     RQTEAMARALKVVGLMNVQFAIQGEGDNAVVYVLEVNPRASRTVPFVSKACSLPLAKI
                     AARCMAGQTLAEQGVGGEIVPPYYSVKEAVFPFVKFPGVDTILGPEMKSTGEVMGVGR
                     SFGEAFVKSQMGAGVRLPTSGTVFISVRPTDKPVAIEVARELHEMGFALVATRGTAAA
                     IEAAGIPVGVVNKVNEGRPHIVDIIKNEEIVLVINTVDEKRQAIADSRSIRTSALAAK
                     VSIFTTIEGARAACMGMRHLSSGLEVYSVQGLHAELKQQA"
     gene            2342..2818
                     /gene="greA"
                     /locus_tag="P5537_11620"
     CDS             2342..2818
                     /gene="greA"
                     /locus_tag="P5537_11620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002928138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0070063 - RNA polymerase binding [Evidence
                     IEA];
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HRV78734.1"
                     /translation="MNKTPLTVAGAEKLRAELHRLKTVERPNVIAAIAEARSHGDLSE
                     NAEYEAAKDRQGFIEGRIMEVESKLANAQIIDPTLLDADGRCVFGATVELEDLESGQV
                     VTYQIVGDDEADIKENKISISSPIARALIGKYAGDIAEVQAPGGVREYEILDVRYV"
     gene            complement(2912..3364)
                     /gene="yhbY"
                     /locus_tag="P5537_11625"
     CDS             complement(2912..3364)
                     /gene="yhbY"
                     /locus_tag="P5537_11625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002928139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HRV78735.1"
                     /translation="MTELTPAERSDLRARAHHLNPVVTVAGNGLTPAVLAEIERALQA
                     HELIKVKVQGAEREQREALMQELCTAVDAAPVQHIGSILVVWRARREDEKTAAPAEKK
                     PARASTAKSAAAFAAAARRAALAKASAESRRSPARAPAPRGRGAARGR"
     gene            3448..4071
                     /locus_tag="P5537_11630"
     CDS             3448..4071
                     /locus_tag="P5537_11630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RlmE family RNA methyltransferase"
                     /protein_id="HRV78736.1"
                     /translation="MKKNKTSRAWVHDHVNDPWVQRAQAEGYRARAAFKLLEIDERDH
                     LLRPGAVVVDLGAAPGSWCQVAVRRCGPKARIFALDLLPMEAVAGVDFLLGDFTEDAV
                     LEELESRLGGASVDVVLSDMAPNLSGVATVDQARSVHLCELALDFAVRHLKPGGQFVV
                     KVFQGEGFMEYRKQMEAAFASVQVRKPKASRDRSAEVYLLGKGPRRP"
     gene            4194..6086
                     /gene="ftsH"
                     /locus_tag="P5537_11635"
     CDS             4194..6086
                     /gene="ftsH"
                     /locus_tag="P5537_11635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011238538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HRV78737.1"
                     /translation="MNNLFKNLAIWMVIGVVLMTVFNQFNTRQTPTSTMEYSQFLEEA
                     KAGRISRATIDGRVLKATTQEGRTITVYTPGVQDIWMVSDLMRYGVQINASKPEEEQS
                     FLASVFVSWFPMLLLIGVWIFFMRQMQGGGKGGAFSFGKSKARMLDESANSVTFADVA
                     GCDEAKEEVAELVEFLRDPSKFQKLGGRIPKGVLMVGSPGTGKTLLAKAIAGEAKVPF
                     FSISGSDFVEMFVGVGAARVRDMFEQAKKQAPCIIFIDEIDAVGRQRGAGLGGGNDER
                     EQTLNQLLVEMDGFEGQTGVIVIAATNRPDVLDPALLRPGRFDRQVVVALPDIRGREQ
                     ILKVHMRKVPIAPDVDPQVLARGTPGFAGADLANLVNEAALFAARANKRLVDMEDFER
                     AKDKIMMGAERRSVVMPEEERRNTAYHESGHAVVARLLDKTDPVHKVTIIPRGRALGV
                     TMQLPTEDRYSQDRDRLLQTIAVLFGGRIAEEIFMKQMTTGASNDFARATDLARRMVT
                     QWGMSDTLGPMVYGEEEGEIFLGRQVTTHRNVSEATMQKVDAEIRRIIDQQYSLARRL
                     LEENSDKVEAMTAALLEWETIDAEQVNDIMAGRPPRPPKPASAPPSRPKDDAPGAAPT
                     APAPAA"
     gene            6186..7016
                     /gene="folP"
                     /locus_tag="P5537_11640"
     CDS             6186..7016
                     /gene="folP"
                     /locus_tag="P5537_11640"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HRV78738.1"
                     /translation="MSVLQCGRFRLDLSQPRVMAIINLTDDSFSGDGLRGDLARALAR
                     AERALEEGAEMLDIGAESTRPGSDPVPEAQELERVVRFVEAARDWGVPLSIDTLKPAV
                     MRAALAAGADMINDINAFRAPGALEAVVAGESGLCVMHMLGQPRTMQEDPRYTDVVGE
                     VIGFLAERVAALEAAGVARERIVLDPGFGFGKRVEHNYALLRELARFGAGGLPVLAGL
                     SRKSMLGAVTGRAVGERLAASVAGALIAVQNGARIVRVHDVAATRDVLAVWRATVTGC
                     "
     gene            7073..8425
                     /gene="glmM"
                     /locus_tag="P5537_11645"
     CDS             7073..8425
                     /gene="glmM"
                     /locus_tag="P5537_11645"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_function: GO:0016868 - intramolecular transferase
                     activity, phosphotransferases [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HRV78739.1"
                     /translation="MARKYFGTDGVRGKVGDAPITPEFVMRLGYAAGVTLVAREKLPA
                     GEHPAVLIGKDTRISGYLLEAALEAGFAAAGVDVMLAGPIPTPAVAYLTRALRLQAGV
                     VISASHNPFYDNGIKFFSADGSKLPDAVEAEIEAHLDEPMGCVDSARLGKARRIDDAA
                     GRYIEFCKSTFPNELDLRGMRIAVDCAHGAAYQIAPKVFHELGAEIIPVGVEPNGLNI
                     NDGVGATRPENLRQAVLKHGADLGIALDGDADRLIMADHRGEIYDGDKLLYVVACARH
                     AEGRLEGVVGTLMSNLGFEHAIERLGAPFARAKVGDRYVLELLQERGWKIGGENSGHI
                     ICLDRHTTGDGIVSALQVLAALKQRGLSLADACADLVFYPQRLINVRMPAGFDWRADG
                     SIASAQAKAEQTLGDSGRVLLRPSGTEPLLRVMVEGRDGDLVERLAREIAGVVEEAIA
                     "
     gene            8576..9616
                     /gene="pstS"
                     /locus_tag="P5537_11650"
     CDS             8576..9616
                     /gene="pstS"
                     /locus_tag="P5537_11650"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042301 - phosphate ion binding [Evidence
                     IEA];
                     GO_process: GO:0035435 - phosphate ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HRV78740.1"
                     /translation="MRFSTKFAAAACSSVLFAASAHALDITGAGASFPAPLYAKWADA
                     YQKASGNRVNYQSIGSGGGIRQIGAKTVDFGASDMPLTPEKLAEGGLQQFPTAIGAVV
                     PVVNIEGVKPGDMKLTGEVLAQIYQGKITKWNDPAIAALNPSLKLTDQDIGVVRRADG
                     SGTTFVFTNYLSKVSTEWKEKIGEGTAVQWPVGLGGKGNEGVSAFVQRLPGSIGYVEY
                     AYAKQNKLSHAIMQNKEGQFVEPNNESFAAAAEGADWSKSAFYEILTNQPGAKSWPIT
                     SATFILMHKVQDKPAQGAEVLKFFDWAYVNGADMALELEYIPMPKATVELIRASWGEM
                     KDSAGNPVFSAK"
     gene            9731..10693
                     /gene="pstC"
                     /locus_tag="P5537_11655"
     CDS             9731..10693
                     /gene="pstC"
                     /locus_tag="P5537_11655"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004333773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstC"
                     /protein_id="HRV78741.1"
                     /translation="MQTTGFKSSASMKFGDRLFGTLAKSFAWLTLILLAGIILALIYA
                     SWPSIQAFGIGFLFSDAWNPPMDEFGALIPIYGTIVTSVIALLIAVPVSFGIALFLTE
                     MAPAWLRRPLGTAIELLAAIPSIVYGMWGLLVFAPIFAKYIQPGLQSSLGQVPVIGKL
                     FAGAPLGIGLLSAGIILAIMIIPYIASVMRDVFEVTPPMLKESAYGVGCTTWEVMWGV
                     VLPYTKTGVIGGVMLGLGRALGETMAVTFVIGNTNFLDSASLFAPGNSITSALANEFA
                     EADPGLHTSALMELGLILFVITLIVLVVSKLLLLRLAKGEGTKS"
     gene            10706..11548
                     /gene="pstA"
                     /locus_tag="P5537_11660"
     CDS             10706..11548
                     /gene="pstA"
                     /locus_tag="P5537_11660"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004333775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0035435 - phosphate ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HRV78742.1"
                     /translation="MNLLARRKLTNRVALTLSLSAMAFGLFWLAWILWTVLELGLSGL
                     SLTLFTEMTPPPGAETGGLLNAIAGSLIMVVLATLLGTPIGILAGVYLAEYGRNHWLG
                     STTRFINDLLLSAPSIVIGLFVYAVVVAQTGKFSAWSGVIALALIVLPVVVRTTENML
                     QLIPNTLREAAFALGAPKSVVISKVTLRAARAGVLTGVLLAVARIAGETAPLLFTALS
                     NQFWTLNLNEPMANLPVTIFKFAMSPFTNWQELAWAGVFLITMGVLALNIIARVFLRA
                     EKIN"
     gene            11629..12393
                     /gene="pstB"
                     /locus_tag="P5537_11665"
     CDS             11629..12393
                     /gene="pstB"
                     /locus_tag="P5537_11665"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011765126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HRV78743.1"
                     /translation="MEITDAQIEFKDFNFYYGKFHALKNINFKMARHKCTAFIGPSGC
                     GKSTLLRTINRMYDLYPEQRADGQLLFDGRNLLGSDIDVSVLRARIGMVFQKPTPFPM
                     SIYDNIAFGVKLHEKLSSSEMDNRVEWALRKAALWDEVKDKLKQSGMSLSGGQQQRLC
                     IARGIAVKPEVILLDEPTSALDPISTARIEELIDELKEEFTIVIVTHNMQQAARISDY
                     TAYMYLGEMVEFGVTDELFVKPKKKETEDYITGRFG"
     gene            12662..13396
                     /gene="tpiA"
                     /locus_tag="P5537_11670"
     CDS             12662..13396
                     /gene="tpiA"
                     /locus_tag="P5537_11670"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HRV78744.1"
                     /translation="MTRLVAGNWKMNGSLAANRDLLDGLVSIPGMEMAVCVPYPYLAQ
                     AQERPAGVVLGAQDVSEYAVGAYTGEVSAAMLVEFGCRYAIVGHSERRALFGEDDATV
                     GRKARAAMQAGLVPIVCVGETLAERDEGRVMEVIGRQLDAVREVLGPVAIGRIVLAYE
                     PVWAIGTGRSASVAQVAEVHAGIRAWLNVHGAAGGVRILYGGSVKPDNAAAIFAVADV
                     DGGLIGGASLAAADFMAICRAAAGGV"
     gene            13428..13778
                     /gene="secG"
                     /locus_tag="P5537_11675"
     CDS             13428..13778
                     /gene="secG"
                     /locus_tag="P5537_11675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004333782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HRV78745.1"
                     /translation="MGDYLFSLVLTVHVLVGLGVIGLVLVQHGKGADMGAAFGSGASG
                     SLFGASGSANFLSRTTAVLATVFFLTSLGLSFLASNKPAAPGSVMEGAQTAPATTPAP
                     AAPVESSPAQSIPK"
     gene            13844..13928
                     /locus_tag="P5537_11680"
     tRNA            13844..13928
                     /locus_tag="P5537_11680"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13878..13880,aa:Leu,seq:gag)
     gene            14036..14410
                     /gene="ndhC"
                     /locus_tag="P5537_11685"
     CDS             14036..14410
                     /gene="ndhC"
                     /locus_tag="P5537_11685"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit A"
                     /protein_id="HRV78746.1"
                     /translation="MLENYFPVLMFMLVGLGFGLAPVILGRLIAPYRPDSEKNSPYEC
                     GFEAFEDARMKFDVRYYLIAILFILFDLEIAFLFPWATVFQEFIAAGEIAWFVFGSVM
                     VFLAILVIGYIVEWKNGALDWE"
     gene            14414..>14494
                     /locus_tag="P5537_11690"
     CDS             14414..>14494
                     /locus_tag="P5537_11690"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018411439.1"
                     /note="The point of entry for the majority of electrons
                     that traverse the respiratory chain eventually resulting
                     in the reduction of oxygen; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit B"
                     /protein_id="HRV78747.1"
                     /translation="MSIEGVFREGFVTTSLDAVINWTRTGS"
BASE COUNT         2338 a         4775 c         4950 g         2431 t
ORIGIN      
        1 tcgtcatcga gatgaacccg cgcgtgtcgc gctcctcggc gctggcctcc aaggccaccg
       61 gcttcccgat cgccaaggtc gccgccaagc tggcggtggg ctacaccctc gacgagctgc
      121 gcaacgacat caccggcggt gccacgccgg cctccttcga gccctcgatc gactatgtcg
      181 tcaccaagat cccgcgcttc gcgttcgaga agttcccgca ggccaacgac cgcctgacca
      241 cccagatgaa gtcggtgggc gaggtcatgg cgatgggccg cagcttccag gagtccttcc
      301 agaaggccct gcgcgggctg gaggtgggcg tgtatggtct ggatgaggtc gaggccgacc
      361 gcgaggacct cgagcacgag ctcgccagcc cgggcgcgca gcgcatctgg tacgtcggcc
      421 aggccttccg cgagggcatg agcctggagc aggtgttcaa cctgtcgaag atcgacccct
      481 ggttcctcgc ccagatcgag gacatcgtgc tctccgagaa ggcgctcgcc gggcgttcgc
      541 tgaaggcgct gcaggccgcc gagctgcgcg agctcaagaa gaagggcttc tccgaccgcc
      601 gcctggccaa gctgctcaac accgacgaga ccgcggtgcg cctgcaccgc cacaccgtgg
      661 gtgtgcgccc ggtgttcaag cgcgtcgaca cctgcgcggc cgagttcgcc acctccaccg
      721 cctacctgta ttcgtcctac gaggacgagt gcgaggcgat gccgaccgag cgcaagaaga
      781 tcatggtgct cggcggcggc cccaaccgca tcggccaggg catcgagttc gactactgct
      841 gcgtgcatgc ggcgctggcg ctgcgcgagg acgggtacga gaccatcatg gtcaactgca
      901 acccggagac cgtgtccacc gactacgaca cctcggaccg cctgtacttc gagccgatca
      961 cgctcgagga cctgctcgag atcgtgcaca tcgagaagcc ggtgggcgtg atcgtccagt
     1021 tcggcggcca gaccccgctc aagcgcgcgc aggcgctcga agagaacggc gtgccgatca
     1081 tcggcaccag cccggacatg atcgacgccg ccgaggaccg cgagcgcttc cagaagctgc
     1141 tcaacgacct gggtctcaag cagccgccca accgcaccgc gcgcacgccc gaacaggccg
     1201 tgcgccttgc ggccgagatc ggctacccgc tggtggtgcg gccgtcctac gtgctcggtg
     1261 gccgcgcgat ggagatcgtg cacgagcaga aggacctcga gcgctacatg cgcgaggcgg
     1321 tcaaggtctc gaacgagtcg ccggtgctgc tcgaccgctt cctcaacgac gccaccgagg
     1381 tggacgtcga tgcgctgtcc gacggcaagc aggtgatgat cggcggcatc atggagcaca
     1441 tcgagcaggc cggcgtgcac tcgggcgact cggcctgctc gctgccgccc tacacgctgt
     1501 cggcgaagct gcaggacgag ctgcgccgcc agaccgaggc catggcgcgt gcgctgaagg
     1561 tcgtcggcct gatgaacgtc cagttcgcca tccagggcga gggcgacaac gcggtggtct
     1621 atgtgctgga agtgaacccg cgcgcctcgc gtaccgtccc cttcgtgtcc aaggcctgct
     1681 cgctgccgct ggcgaagatc gccgcgcgct gcatggccgg ccagacgctg gcagagcagg
     1741 gcgtcggcgg cgagatcgtg ccgccgtact actcggtcaa ggaggcggtg ttcccgttcg
     1801 tgaagttccc gggcgtggat accatcctcg ggcccgagat gaagtccacc ggcgaggtca
     1861 tgggcgtggg ccgcagcttc ggcgaggcct tcgtcaagag ccagatgggc gcgggcgtgc
     1921 gcctgccgac ctcgggcacg gtgttcatca gcgtgcgccc gaccgacaag ccggtcgcga
     1981 tcgaggtcgc acgcgagctg cacgagatgg gcttcgcgct cgtcgccacg cgcggcaccg
     2041 cggcggcgat cgaggccgcc gggattcccg tgggcgtggt caacaaggtc aacgaggggc
     2101 gtccgcacat cgtcgacatc atcaagaacg aggagatcgt gctggtgatc aacaccgtcg
     2161 acgagaagcg ccaggcgatc gccgactcgc gctcgatccg caccagcgcg ctcgccgcca
     2221 aggtgtcgat cttcaccacc atcgagggtg cgcgcgccgc ctgcatgggc atgcgccacc
     2281 tctcgagcgg tctcgaggtg tattccgtgc agggcctgca cgccgaactg aagcagcaag
     2341 catgaacaag accccgctta ccgtcgccgg cgccgagaag ctgcgcgcag aactgcatcg
     2401 gctgaagacc gtcgagcgtc ccaacgtgat cgccgcgatc gccgaggcgc gctcgcacgg
     2461 cgacctctcc gagaacgccg agtacgaggc cgccaaggat cgccagggct tcatcgaggg
     2521 gcgcatcatg gaggtcgagt ccaagctcgc caacgcgcag atcatcgatc cgacgctgct
     2581 cgatgcggac ggtcgctgcg tgttcggcgc cacggtcgag ctcgaggacc tcgagtcggg
     2641 ccaggtggtg acttaccaga tcgtcggcga cgacgaggcc gacatcaagg aaaacaagat
     2701 ctcgatcagc tcgccgatcg cgcgtgcgct gatcggcaag tacgccgggg atatcgccga
     2761 ggtgcaggcg cccggtggcg tgcgcgaata cgagatcctg gacgtgcgct acgtctgagg
     2821 ggtgcggggt ggcgtggagc tgaagagggc ggtgcgatgc accgcctctt cgtttgcagc
     2881 cgcggcgcgg ggcgcgccgg gcggggggtg ctcagcgccc gcgtgcggcg ccgcgtccgc
     2941 gcggggcggg cgcgcgagcg ggcgagcggc gcgactcggc gctcgccttg gcgagcgcgg
     3001 cgcgacgcgc ggcggcggcg aaggccgcgg ccgacttggc ggtggaggcg cgcgccggct
     3061 tcttctcggc gggcgcggcg gtcttctcgt cctcgcggcg tgcgcgccac acgacgagga
     3121 tgctgccgat gtgctgcacc ggggcggcgt ccaccgcggt gcacagctct tgcatcaggg
     3181 cctcgcgctg ctcgcgttcg gcgccctgga ccttgacctt gatgagctcg tgcgcctgca
     3241 gggcgcgctc gatctcggcg aggacggctg gcgtgaggcc gttgccggcg acggtcacga
     3301 cggggttcag gtggtgggcg cgggcgcgaa ggtcgctgcg ctcggccggg gtaagctcgg
     3361 tcattgcaaa tctctggatg ggtgaagccc gggacgcgga ttctaccccg tgcgtgccat
     3421 gcatggccgt cgcggatgga gcaagggatg aagaagaaca agaccagccg tgcctgggtg
     3481 cacgatcatg tgaacgatcc ctgggtgcag cgcgcccagg ccgagggcta tcgcgcgcgc
     3541 gccgccttca agctgctcga gatcgacgag cgcgaccacc tgctgcggcc cggcgcggtg
     3601 gtggtggatc tgggcgcggc gcccggctcc tggtgccagg tcgcggtccg gcgctgcggc
     3661 ccgaaggcgc gcatcttcgc cctcgacctg ctgccgatgg aggcggtggc gggggtggat
     3721 ttcctgctcg gcgacttcac cgaggacgcc gtgctcgagg agctcgagtc gcgcctcggc
     3781 ggcgcgagcg tcgacgtggt gctctcggac atggcgccga acctttccgg ggtcgcgacg
     3841 gtcgaccagg cacgttcggt ccatctgtgc gaactcgcgc tcgacttcgc ggtgcggcat
     3901 ctgaagccgg gcgggcagtt cgtggtcaag gtgttccagg gcgagggctt catggagtat
     3961 cggaagcaga tggaggcggc gttcgcgtcg gtgcaggtgc gcaagcccaa ggcctcgcgc
     4021 gaccgcagcg ccgaggtcta tctgctcggc aaggggccgc gccgtccctg agtcggcgtg
     4081 ctgggatggc gatcgggttg cgctatgggt cccattggtt tgcccgtggg aacaatcgcc
     4141 actagaatcg gtcagtcgcg tacaggccgc aatggctttc ggggaacaga aagttgaaca
     4201 atctcttcaa gaatctcgcg atctggatgg tcatcggcgt agtgctgatg accgtattca
     4261 accagttcaa cacgcgccag acgccgacca gcacgatgga gtactcccag ttcctggagg
     4321 aggccaaggc cggacggatc tcgcgtgcga ccatcgatgg gcgcgtgctc aaggcgacga
     4381 cgcaggaagg gcgcacgatc acggtctata cgcctggcgt gcaggacatc tggatggtct
     4441 ccgacctgat gcgctacggc gtgcagatca acgccagcaa gcccgaggag gagcaatcct
     4501 tcctggccag cgtgttcgtg tcctggttcc cgatgctgct gctgatcggc gtgtggatct
     4561 tcttcatgcg ccagatgcag ggaggcggca agggcggggc gttctcgttc ggcaagagca
     4621 aggcgcgcat gctcgacgag tcggccaact cggtgacctt cgccgacgtc gctggttgcg
     4681 acgaggcgaa ggaagaagtc gccgaactgg tggagttcct gcgtgaccca tcgaagttcc
     4741 agaagctcgg cggtcgcatc ccgaagggcg tgttgatggt cggctctccg ggcaccggca
     4801 agaccctgct cgccaaggcg atcgccggcg aggccaaggt tcccttcttc tccatctccg
     4861 gttccgactt cgtcgagatg ttcgtcggcg tgggtgcggc gcgcgtgcgc gacatgttcg
     4921 agcaggccaa gaagcaggcg ccgtgcatca tcttcatcga cgagatcgac gcggtcggcc
     4981 gccagcgtgg cgccggcctc ggtggcggca acgacgagcg cgagcagacg ctcaaccagc
     5041 tgctggtcga gatggacggc ttcgagggcc agaccggcgt gatcgtgatc gcggcgacca
     5101 accgccccga tgtcctcgac ccggccctgc tgcgcccggg ccgcttcgac cgccaggtgg
     5161 tggtggcgct tcccgacatc cgcggccgcg agcagatcct caaggtgcac atgcgcaagg
     5221 tgccgatcgc acccgacgtc gatccgcagg tgctggcgcg cggcacgccc ggcttcgccg
     5281 gtgccgacct tgccaacctg gtgaatgagg ccgccctgtt tgccgcgcgc gccaacaagc
     5341 gcctggtcga catggaagac ttcgagcgcg ccaaggacaa gatcatgatg ggggccgagc
     5401 gccgctcggt ggtcatgccc gaggaggagc gccgcaacac cgcctaccac gagtccggcc
     5461 acgcggtggt cgcccgcctg ctcgacaaga ccgatccggt gcacaaggtc accatcatcc
     5521 cgcgtggccg tgcgctcggc gtgacgatgc aactgcctac cgaggatcgc tacagccagg
     5581 atcgtgaccg cctgctgcag accatcgcgg tgctgttcgg cggccgcatc gccgaagaga
     5641 tcttcatgaa gcagatgacc accggcgcgt cgaacgactt cgcccgcgcc accgacctcg
     5701 cgcgccgcat ggtgacgcag tggggcatgt ccgacacgct cgggccgatg gtgtatggcg
     5761 aggaggaggg cgagatcttc ctcggccgcc aggtcaccac gcaccgcaac gtgtccgagg
     5821 cgacgatgca gaaggtcgat gcggagatcc gccgcatcat cgaccagcag tattcgctgg
     5881 cacgtcgcct gctcgaggag aacagtgaca aggtcgaggc gatgacggcc gcgctgctgg
     5941 agtgggagac catcgatgcc gagcaggtga acgacatcat ggccggccgc ccgccgcgtc
     6001 cgcccaagcc ggcctcggcg ccgcccagcc ggccgaagga cgatgcgccg ggtgcggcgc
     6061 ccacggcgcc tgcacccgca gcctgagttc gacacatccg cttcacgggg ccggccagac
     6121 cggccccttt ccattccggc gcccgcatgc tgccgtgcgg gcgcatcgat catcacgagg
     6181 gttcgatgtc cgtcctccaa tgcggccgct tccggctcga tctgtcccag cccagggtga
     6241 tggcgatcat caacctcacc gacgactcct tctccggcga cggcctgcgc ggcgatctcg
     6301 cccgtgcgct ggcgcgtgcc gagcgtgcgc tggaggaggg cgcggagatg ctcgacatcg
     6361 gcgccgagtc cacccgaccg ggctccgacc cggtgccgga ggcccaggaa ctcgagcgcg
     6421 tggtgcgctt cgtcgaggcc gcgcgcgact ggggggtgcc gctttccatc gacaccctga
     6481 agcctgcggt gatgcgcgcg gcgctcgcgg cgggggcgga catgatcaac gacatcaacg
     6541 cgtttcgcgc gccgggcgcg ctcgaggcgg tcgtcgcggg cgagtccggg ctgtgcgtga
     6601 tgcacatgct cggccagccg cgcacgatgc aggaggaccc gcgctacacc gacgtggtcg
     6661 gcgaggtgat cggtttcctc gccgagcgcg tggccgccct cgaggcagcg ggcgtggcac
     6721 gcgagcgcat cgtgctcgat cctggcttcg gcttcggcaa gcgcgtcgag cacaactacg
     6781 cgctgctccg cgaactcgcg cgcttcggtg cgggcgggct gccggtgctg gccgggctgt
     6841 cgcgcaagtc catgctcggt gcggtgaccg gtcgcgcggt cggcgagcgg ctcgccgcca
     6901 gcgttgccgg tgcgttgatc gcggtgcaga acggcgcgcg catcgtgcgg gtgcacgacg
     6961 tcgccgccac ccgcgacgtg ctcgcggtct ggagggcgac cgtgacgggt tgctgagcaa
     7021 ggcgctgcct gcggtgtcat aatctgcgct ttcgaaagtt gctggagcga agatggcgcg
     7081 caagtatttc ggcaccgatg gtgtgcgcgg caaggttggc gacgcgccga tcacgccgga
     7141 gttcgtgatg aggctgggct atgcggccgg cgtgaccctg gtcgcgcgcg agaagctgcc
     7201 cgcaggcgag cacccggcgg tgctgatcgg caaggacacg cggatctccg gctacctgct
     7261 cgaggcggcg ctggaggccg gcttcgccgc ggccggcgtg gatgtgatgc tggccgggcc
     7321 gatcccgacc ccggccgtgg cctatctcac gcgcgcgctg cgcctgcagg ccggcgtggt
     7381 gatctcggcc tcgcacaacc ccttctacga caacgggatc aagttcttct cggccgacgg
     7441 cagcaaactg cccgatgcgg tcgaggccga gatcgaggcc cacctcgacg agccgatggg
     7501 ttgcgtggac tccgcccgtc tcggcaaggc gcgccgcatc gacgatgcgg ccggacgcta
     7561 catcgagttc tgcaagagca ccttccccaa cgagctcgat ctgcgcggca tgcgcatcgc
     7621 ggtggactgc gcccacggcg cggcctacca gatcgcgccc aaggtgttcc acgagcttgg
     7681 cgccgagatc atcccggtgg gcgtcgagcc caacggcctc aacatcaacg acggcgtcgg
     7741 cgcgacgcgg ccggagaacc tgcgccaggc ggtgctcaag cacggcgccg acctcggcat
     7801 cgcgctcgac ggcgacgccg accgcctgat catggcggac caccgtggcg agatctacga
     7861 cggcgacaag ctgctctacg tggtggcgtg cgcgcgccac gcggaaggtc gcctcgaggg
     7921 cgtggtcggc acgctgatga gcaacctcgg cttcgagcac gccatcgagc gtcttggcgc
     7981 gcccttcgcg cgcgcgaagg tgggtgaccg ctacgtgctc gagctgctgc aggaacgcgg
     8041 ctggaagatc ggtggcgaga actccggaca catcatctgc ctcgatcgcc acaccaccgg
     8101 cgatggcatc gtctcggcgc tgcaggtgct ggccgcgctg aagcagcgcg ggctttcgct
     8161 ggccgacgcc tgcgccgacc tggtgttcta cccgcagcgc ctgatcaacg tgcgcatgcc
     8221 cgctggcttc gactggcgcg cggacggttc gatcgcgagc gcacaggcga aggcggagca
     8281 gacgctcggc gacagcggac gcgtgctgct gcgcccctcg ggcaccgagc ccctgttgcg
     8341 cgtgatggtc gaaggccgcg acggcgacct cgtcgagcgt ctcgcacgcg agatcgccgg
     8401 cgtggtcgag gaagcgatcg cctgactcgg cgggcatgaa gtgggcggac ggtgcgcaac
     8461 gcgccgtccg cgcgcgggaa ggggggcaaa tcttcccgtt cgatgacacg caacgtggct
     8521 gtaacaatcg cttgttacct tacgggctca gtcttccaac cccgaggtag tcaccatgcg
     8581 tttctccacg aagtttgccg ccgccgcatg ttcgtccgtg ctgttcgccg ccagcgccca
     8641 tgcgctcgac atcacgggcg cgggcgcttc cttcccggcg ccgctgtacg cgaagtgggc
     8701 cgatgcctac cagaaggctt cgggcaaccg cgtgaattac cagtcgatcg gctcgggtgg
     8761 cggcatccgc cagatcggtg ccaagaccgt cgacttcggc gcgtccgaca tgccgctgac
     8821 ccccgagaag ctcgccgagg gcggcctgca gcagttcccc accgcgatcg gcgcggtcgt
     8881 gccggtggtg aacatcgagg gtgtcaagcc gggcgacatg aagctcaccg gtgaagtgct
     8941 ggcccagatc taccagggca agatcaccaa gtggaacgat ccggcgatcg ccgcgctgaa
     9001 ccccagcctc aagctcaccg accaggacat cggcgtcgtg cgtcgcgcgg acggttcggg
     9061 caccaccttc gtgttcacca actacctctc caaggtctcg accgagtgga aggagaagat
     9121 cggtgaaggc accgcggtgc agtggccggt gggcctcggc ggcaagggca acgagggcgt
     9181 gtcggccttc gtgcagcgtc tgccgggctc gatcggctac gtcgagtacg cctacgccaa
     9241 gcagaacaag ctctcccacg cgatcatgca gaacaaggaa ggccagttcg tcgagccgaa
     9301 caacgagagc ttcgccgctg ccgccgaagg cgccgactgg tcgaagtccg cgttctacga
     9361 gatcctgacc aaccagccgg gcgcgaagtc gtggccgatc acgagcgcca ccttcatcct
     9421 catgcacaag gtgcaggaca agccggcgca gggcgccgag gtgctgaagt tcttcgactg
     9481 ggcctacgtg aatggcgccg acatggcgct cgagctcgag tacatcccga tgcccaaggc
     9541 cacggtcgag ctcatccgcg cctcctgggg cgagatgaag gacagcgccg gcaacccggt
     9601 cttctcggcc aagtaagccg gagtcggccc cgtggctcga tccagcgtcc agccaggggc
     9661 ccccggggcc cttggccaca aactttccgc ggggggcggc gcagatgcgg ccgccctttc
     9721 tggtgtcccc atgcaaacga ccggattcaa gtcgtcggcg tcgatgaagt tcggcgacag
     9781 actgttcggt accctggcga aatccttcgc ctggttgacc ctgatcctgc tcgccgggat
     9841 catcctcgcc ctgatctacg cctcctggcc cagtatccag gccttcggca tcggcttcct
     9901 gttctccgat gcctggaatc cgccgatgga cgagttcggc gcgctgatcc cgatctacgg
     9961 caccatcgtt acctcggtga tcgcgctgct gatcgccgtg ccggtgagct tcggcatcgc
    10021 gctcttcctc accgagatgg cgccggcctg gctgcgacgc ccgctcggca ccgcgatcga
    10081 gctgctcgcg gcgattccct cgatcgtgta cggcatgtgg gggctgctgg tgttcgcgcc
    10141 catcttcgcc aagtacatcc agcccggcct gcagtcctcg ctcggccagg tgccggtgat
    10201 cggcaagctc ttcgccggcg cgccgctcgg catcggcctg ctgtccgcgg gcatcatcct
    10261 ggcgatcatg atcatcccct acatcgcctc ggtgatgcgc gacgtattcg aggtcacgcc
    10321 gccgatgctc aaggagtccg cctacggcgt gggctgcacc acctgggagg tgatgtgggg
    10381 cgtggtgctg ccctacacca agaccggcgt gatcggaggc gtcatgctcg gcctcggtcg
    10441 tgcgctcggt gagaccatgg cggtcacctt cgtgatcggc aacaccaact tcctcgactc
    10501 ggcatcgctg ttcgcgccgg gcaacagcat cacctcggcg ctggccaacg agttcgcgga
    10561 agcggatccg ggcctgcata cctcggcatt gatggaactg ggcctgatcc tgttcgtgat
    10621 cacgctgatc gtgctggtgg tgtcgaagct gttgctgctg cgtctcgcca agggcgaggg
    10681 tacgaagagc tgaccgggga acgacatgaa ccttctcgct agacgcaaac tcaccaaccg
    10741 ggtggcgctg accctgtcgc tgtcggccat ggccttcggc ctgttctggc tcgcctggat
    10801 cctgtggacc gtgctcgagc tcggtctctc cgggctctcg ctgacgctct tcaccgagat
    10861 gacgccgccg cccggcgccg agaccggggg cctgctcaac gcgatcgccg gcagcctgat
    10921 catggtcgtg ctggcaaccc tgctcggcac cccgatcggc atcctcgccg gggtgtatct
    10981 cgccgagtac ggccgcaatc actggctggg ctcgaccacg cgcttcatca acgacctgct
    11041 gctgtcggcg ccgtccatcg tgatcggtct cttcgtgtat gcggtggtcg ttgcgcagac
    11101 cggcaagttc tccgcctggt cgggggtgat cgcgctcgcg ctgatcgtgc ttccggtggt
    11161 tgtgcgcacc accgagaaca tgctgcagct gatcccgaac acgctgcgcg aggcggcctt
    11221 cgccctcggt gcgcccaaga gcgtggtgat ttccaaggtc accctgcgtg cggcgcgtgc
    11281 gggcgtgctc accggggtgc tgctggccgt ggcgcgtatc gccggcgaga ccgcgccgct
    11341 gctcttcacc gcgctctcca accagttctg gacgctgaac ctgaacgagc cgatggccaa
    11401 cctgccggtc acgatcttca agttcgccat gagccccttc accaactggc aggaattggc
    11461 ctgggcaggt gtgttcctga tcacgatggg ggtgctcgcg ctcaacatca tcgcgcgcgt
    11521 cttcctgcgc gccgagaaga tcaactaagg ctcaaccaag gatcaatccg gctatccgcc
    11581 gcacgcaatc cgtgcccgcc gccgtgcggg ccgggattgg agaaaagaat ggaaatcacc
    11641 gacgcgcaga tcgagttcaa ggacttcaac ttctattacg ggaagttcca cgcgctcaag
    11701 aacatcaact tcaagatggc gcgccacaag tgcaccgcct tcatcggccc ctcgggctgc
    11761 ggcaagtcga cgctgctgcg tacgatcaac cgcatgtacg acctctatcc cgagcagcgc
    11821 gccgacggac agctcctctt cgacggccgc aacctgctcg gctccgacat cgacgtcagc
    11881 gtgctgcgcg cgcgcatcgg catggtcttc cagaagccga cgcccttccc gatgtcgatc
    11941 tacgacaaca tcgccttcgg cgtgaagctg cacgagaagc tttcgagcag cgagatggac
    12001 aaccgcgtcg agtgggcgct gcgcaaggcc gcgctgtggg acgaggtcaa ggacaagctc
    12061 aagcagagcg gcatgagcct ctccggcggc cagcagcagc gcctgtgcat cgcgcgcggg
    12121 atcgcggtca agcccgaggt gatcctgctc gacgagccga cctcggcgct cgatccgatc
    12181 tcgacggcgc gcatcgagga actgatcgac gagctgaagg aagagttcac catcgtcatc
    12241 gtcacccaca acatgcagca ggcggcgcgg atttccgact acaccgccta catgtacctc
    12301 ggcgagatgg tggagttcgg cgtcaccgac gagctcttcg tgaagccgaa gaagaaggag
    12361 accgaggact acatcaccgg tcgcttcggc tgaacgatcg acagcacgag cgggcggaag
    12421 cgggcctcgt acgccgcttc cgcctttctt ttcaccaacg ttccaagaat tcttggaatg
    12481 actcggcagg ctcttgctcg atccatccag gcgggatcga cgccatggtg gggcggctgg
    12541 ggcgcgtgcg tcgggggcga ggcgggatcc gaatgcgcct tgccgacgtg ggtcgcgttg
    12601 cggctgatcg gccgcaagcc ttataatcct gcggtttatc tccacggaca ttccccgccc
    12661 catgaccaga ctcgttgccg gtaactggaa gatgaacggc agcctcgcgg ccaatcgcga
    12721 cctgctcgac ggcctcgtgt cgatcccggg gatggaaatg gcggtctgcg tgccctatcc
    12781 ctatcttgcc caggcgcagg agcggcccgc cggcgtggtg ctcggcgcgc aggacgtgtc
    12841 ggagtacgcg gtcggtgcct acacgggcga ggtgagcgcg gccatgctcg tggagttcgg
    12901 ttgccgctac gccatcgtcg ggcactccga gcgtcgtgcg ctcttcggtg aggacgacgc
    12961 cacggtgggg cggaaggcgc gggctgccat gcaggcgggg ctggtgccga tcgtgtgcgt
    13021 gggtgaaacg ctcgccgagc gcgacgaggg gcgtgtcatg gaggtcatcg ggcggcagct
    13081 cgacgccgta cgcgaggtcc tcggccccgt ggcgatcggc cggatcgtgc tcgcctacga
    13141 gccggtgtgg gcgatcggta ccgggcgctc cgcgagcgtg gcgcaggtgg ccgaggtgca
    13201 tgccgggatt cgcgcctggc tgaatgtcca cggcgcggcc ggaggggtgc gcatcctcta
    13261 cggcggcagc gtcaagccgg acaatgccgc ggcgatcttc gccgttgcgg atgtcgacgg
    13321 tgggctgatt ggtggcgcct cgctcgccgc ggcggatttc atggccatct gccgcgccgc
    13381 ggctggtggg gtctgagttt caactgttct atctttcagg attcaagatg ggtgactatc
    13441 tcttctctct cgtgctcacc gtgcatgtgc tggtgggtct cggcgtgatc gggctcgtgc
    13501 tcgtgcagca cggcaagggc gccgacatgg gggcggcctt cggcagcgga gcctcgggca
    13561 gcctcttcgg cgcatcgggt tcggcgaact tcctcagccg taccacggcg gtgctggcca
    13621 cggtgttctt cctgaccagc ctgggtctga gcttcctcgc cagcaacaag ccggcggccc
    13681 cgggtagcgt catggaaggg gctcagaccg cccccgcgac gacccccgcg ccggctgcgc
    13741 cggtcgagtc ctcgccggcg cagtccatcc cgaaataatt ggttgcgagc cctttgcgca
    13801 gtgcgggaaa acacttataa ttatcgcgct gtcagaacga agcgccgacg tggtgaaatt
    13861 ggtagacacg ctatcttgag ggggtagtgg cgaaagccgt atgagttcga gtctcatcgt
    13921 cggcaccaca ttccgggaac gcccgcagaa gcgggcgttt ccacgcaggg ctgagcaata
    13981 acaataattg cggcgcgcaa atgacgccgc ggacttcaaa tgggggtttc cggacatgct
    14041 ggaaaattat tttcccgtcc tgatgttcat gctcgtcggc ctcggcttcg gccttgcgcc
    14101 cgtcatcctc gggcggctca tcgcccccta tcggcctgat tccgaaaaga attctcccta
    14161 cgaatgcggc ttcgaggcgt ttgaagacgc ccgcatgaag ttcgacgtcc gctactacct
    14221 gatcgccatt ctcttcatcc tgttcgacct cgaaatcgcc tttctctttc cgtgggcgac
    14281 ggtcttccag gagttcatcg ccgccggcga aatcgcctgg ttcgtattcg gctcggtgat
    14341 ggtttttctg gcgattctgg tcattggcta tatcgtcgag tggaaaaacg gcgcactcga
    14401 ctgggagtaa tgcatgagca ttgagggcgt cttccgcgag gggttcgtca ccacctcgct
    14461 cgatgcggtc atcaactgga cgcgcaccgg ctcg
//
LOCUS       DAOTIN010000079        14460 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_5015_length_14460_cov_9.139813, whole genome shotgun sequence.
ACCESSION   DAOTIN010000079 DAOTIN010000000
VERSION     DAOTIN010000079.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 14460)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 14460)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14460
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5015_length_14460_cov_9.139813"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..462
                     /locus_tag="P5537_11695"
     CDS             <1..462
                     /locus_tag="P5537_11695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemerythrin domain-containing protein"
                     /protein_id="HRV78748.1"
                     /translation="FELMASMIEYIEMVPEKVHHPKEDTYLFARLRERSAEALPIIER
                     LEAEHREGDARIAALRSALEAYRREGEAGLAGFQAALKTYIEHEWQHMNTEEHLIFPL
                     ARKHLSAEDWAQIDAAFLANDNPWQGPAGKYAALFTRIVNTAPAPVGLGGG"
     gene            complement(664..1377)
                     /locus_tag="P5537_11700"
     CDS             complement(664..1377)
                     /locus_tag="P5537_11700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FCD domain-containing protein"
                     /protein_id="HRV78749.1"
                     /translation="MLHTSPPYAVRQETEVAEPKTLVEAAYRSLRRNIIEGRLSPGEK
                     LRIEHIKNDYGVGGATLREALSLLTSDALVVSQGQRGFRVAPVSLEDLADITETRVML
                     ECSALRQSIALGDDAWEADLTAAFHRLTRAEEKLAEGNNREQWEERNRIFHEVLIAAC
                     PSRWTKHFLSILYHQAERYRHLSLRRSEGTRRLHDEHAALFEAAMARDADTATRLLGE
                     HIRLTLQSVRLDNASTASH"
     gene            1699..2550
                     /locus_tag="P5537_11705"
     CDS             1699..2550
                     /locus_tag="P5537_11705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="HRV78750.1"
                     /translation="MSIGKIGVVGAGTMGNGITQAFAVAGRAVVMMDIGEAQVQRGLA
                     TISASLDRLIKKDRMSAEQKAAAMACITTVTSLEALADCDLVIEAATENVDLKLRIFA
                     DLDRIVKPEAILASNTSSISITRLAAGTQRPGQVIGMHFFNPVPVMALVELINGLQTS
                     AATYTAVEDVAKAIGKTPIKVKNSPGFVVNRMLCPMINEAVFALGEGLATAAEIDEAM
                     KLGCNHPIGPLALCDLIGLDVELAVMQVLYEGTKDPKYRPAPLLVEMLEAGYLGRKSG
                     KGFYDYK"
     gene            complement(2637..3896)
                     /gene="rho"
                     /locus_tag="P5537_11710"
     CDS             complement(2637..3896)
                     /gene="rho"
                     /locus_tag="P5537_11710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HRV78751.1"
                     /translation="MSELKALHVSQLLQMAMDAGVEGANRLRKQELVFALLRNRARRG
                     EPICGDGALEVLPDGFGFLRSPDTSYLAGTDDIYVSPSQIRRFNLRTGDTIEGEIRTP
                     KDGERYFALTKLDKINGRPPEECKTKILFENLTPLHPQECLKLEREVRGEENITSRII
                     DMIAPIGKGQRGLLVAPPKSGKTVMLQHIAHAITANHPDVKLIVLLIDERPEEVTEML
                     RSVKGEVVASTFDEPATRHVQVAEMVIEKAKRLTEHKYDVVILLDSLTRLARAYNTVV
                     PASGKVLTGGVDANALQKPKRFFGAARNIEEGGSLTIIATTLVDTGSRMDDVIYEEFK
                     GTGNMELHLDRRMAEKRVYPAINVNRSGTRREELLLKSDVLQKVWILRKLLYGMDDID
                     AMEFLLDKVKATKSNAEFFDAMRTGRG"
     gene            complement(4075..4401)
                     /gene="trxA"
                     /locus_tag="P5537_11715"
     CDS             complement(4075..4401)
                     /gene="trxA"
                     /locus_tag="P5537_11715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008073352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA];
                     GO_process: GO:0006662 - glycerol ether metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxA"
                     /protein_id="HRV78752.1"
                     /translation="MSEHIHHVTDGNFDSEVLQSQTPVLVDYWAEWCGPCKMIAPILD
                     DVAKDYAGKLKVAKLNIDDNQDTPAKYGIRGIPTLMLFKGGNVEATKVGALSKSQLTA
                     FIDSNI"
     gene            4758..5081
                     /locus_tag="P5537_11720"
     CDS             4758..5081
                     /locus_tag="P5537_11720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin family protein"
                     /protein_id="HRV78753.1"
                     /translation="MTYVVTERCIRCKYTDCVDVCPVDCFREGPNFLVIDPEECIDCT
                     LCVAECPVEAIYSEDDVPDDQKEYIALNAELAKQWKPIVERKDPLPDADHWARIKGKL
                     GELKR"
     gene            5174..5623
                     /locus_tag="P5537_11725"
     CDS             5174..5623
                     /locus_tag="P5537_11725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HRV78754.1"
                     /translation="MLVSEILAIKGKVLFTIGPNRPIAEAVEIMNEQDVGSLVVFSRG
                     EMVGMLTFRQVLQAVQRGGADWQALQVEEVMLREPRAAAPDMEMDELRRLMVEHHQRY
                     LPVMDGTTLLGVVSFHDVAKAVLEEQSFENRMLKNYIRNWPAGEGEE"
     gene            5837..7498
                     /locus_tag="P5537_11730"
     CDS             5837..7498
                     /locus_tag="P5537_11730"
                     /EC_number="6.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain-fatty-acid--CoA ligase"
                     /protein_id="HRV78755.1"
                     /translation="MEKIWLKSYPPGIPAEIDVDAFRSLGDLFERSVARFADKPAYHC
                     MGKSITYAELDALSARFGAWLQSELKLPAGGRVALMMPNVLQYPIALFGTLRAGYTVV
                     NVNPLYTARELEHQLKDSGAEAIVILENFAHTLEHVRAQVSVRHIVVTSLGEMLGLVK
                     GTIVDFVVRKVRKLVPAWRLDGHVRFSTALQRGAAHKLQPATVGHDDIAFLQYTGGTT
                     GVAKGAMLTHRNIIANLQQAHAWIAPYVGEGREIIITALPLYHIFSLTANCLTFLKIG
                     AKNVLIPNPRDIPGFIKELGQHRFTAITGVNTLFNALLNNPEFARLDFSTLRVSLGGG
                     MAVQQVVAEKWKKVTGVSLVEAYGLTETSPAVTINPLDIAEFNHSIGLPVSSTEISIR
                     DDAGNEVPLGQRGELCVRGPQVTPGYWRRPEETARVFTHDGFLRTGDIATVDEHGFVR
                     LVDRKKDMILVSGFNVYPNEVEDVVASHPGVLEVAAVGVPDERSGEAVKIFVVRKDAG
                     LTAEALVAFCRENLTGYKVPHHVEFRDELPKSNVGKILRRELRPK"
     gene            7844..9511
                     /gene="ilvB"
                     /locus_tag="P5537_11735"
     CDS             7844..9511
                     /gene="ilvB"
                     /locus_tag="P5537_11735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004333511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HRV78756.1"
                     /translation="MMQMTGAQLMVRLLERQGVRTVAGIPGGAILPFYDALSGSEQIH
                     HVLARHEQGAGFIAQGMARVSGVPQVCIASSGPGATNLVTAIADACLDSIPMVVITGQ
                     VPQAMIGTDAFQEVDIYGITVPITKHNFLVRSARDLLEVVPDAFRIAMSGRPGPVLID
                     VPKDVQNQLVEVADFPAPAVADPAPQLDLAAVELAAKMINEAEQPVLYLGGGVINSGA
                     APLAAQLAEQAGLPTTMTLMALGAMPMDHPLSIGMLGMHGARYTNFVLEEADLLVCVG
                     ARFDDRAIGRAAQFCPNAKIVHIDIDRSELHKIKSAHVAIHANVKCALEALLPRVQAT
                     LRKRWLSHVDSLKTRFPMQFPGQDDPRTHYGLIHAVAAALDDRAIVATDVGQHQMWVA
                     QAYPFRRPRQWLTSGGLGTMGFGLPTAIGAALAEPDRTVVCFTGDGSFKMNIQELATL
                     AEEGLNVKIVLMNNNALGLVYQQQTLFYGQRLFASKYRTEPDFVKIAEGFGVPAVDLD
                     LADNPRAALAEALHRPGPCLIHATIDREQFVYPMVPPGAANTEMIGG"
     gene            9511..9828
                     /gene="ilvN"
                     /locus_tag="P5537_11740"
     CDS             9511..9828
                     /gene="ilvN"
                     /locus_tag="P5537_11740"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HRV78757.1"
                     /translation="MMIEQVADPLPQAGYAKVVLELDVNNHPGVMSHICNLFARRAFN
                     VEGILCMPVSDGKRSRIWLLVFEDQRLEQMVRQLEKLEDVLNVRRHGAEHEVFERLEG
                     FFH"
     gene            9924..11054
                     /gene="aroC"
                     /locus_tag="P5537_11745"
     CDS             9924..11054
                     /gene="aroC"
                     /locus_tag="P5537_11745"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HRV78758.1"
                     /translation="MSGNTLGTLFTVTSFGESHGPAIGCIVDGCPPGLALCEADIQAE
                     LDRRKPGTSRHVTQRREPDTVEILSGVFEGVTTGTPISLLIRNQDQRSKDYGNIADTF
                     RPGHADYAYLQKYGLRDHRGGGRSSARETAVRVAAGAIAKKWLKERHGIVIRACMGAL
                     GPLEIPFVSWDEVDGNPFFAPNAAIVPELEAYMDALRKSGDSIGARIDVVASGVPVGW
                     GEPVYGRLDADIAYAMMGINAVKGVEIGAGFKAVAQRGTEHGDEMTPEGFLSNHAGGV
                     LGGISTGQDILASIAIKPTSSLRLERRSIDRAGNPVMVATEGRHDPCVGIRATPIAES
                     MLALVLIDHALRHRAQCGDVRTDTPRIPALAPEGRQRLPSPR"
     gene            11136..12305
                     /locus_tag="P5537_11750"
     CDS             11136..12305
                     /locus_tag="P5537_11750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004265815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HRV78759.1"
                     /translation="MIPYWRLSAYYFFYFAFVGAFSPYFTLYLQSIALSATDIALLMS
                     LMQLMRVLAPNLWGWLAERLGMRIAIVRLSALASLAGFSVFFLTTEFAGLFAAMALMA
                     FFWSAVLPLIEGLAFAHLGEQAHRYGSIRVWGSVGFIVAVLALGHSLDRLPIEAVLWV
                     TVSILAGIVLCSFIVPEAPRPPPQRDAASFGDTLRRPEVQALLGACFLMSAAHGALYV
                     FYSIYLVDIGYDKGLVGWMWTLGVLAEIVVFMWMPRLTRRFSLRAILLFSFACAVGRF
                     LMIGWGAHSLVLLLLAQVLHGATFGAYHAAAIAVVNEWFPGRLQSRGQALYGSISFGA
                     GGMLGGLLSGYTWEGIGPAWTYTIGSGFALAGLLWLLLGWKREPGAAEGLHEPRR"
     gene            12313..13128
                     /locus_tag="P5537_11755"
     CDS             12313..13128
                     /locus_tag="P5537_11755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HRV78760.1"
                     /translation="MQSILKIALPVLLAGTITTACQTVQTTHGGAVGVQRSQLMMVSA
                     QEVEQASSQQYQQMVAEARRKNALDRDPATVQRVRRIVSRLTAQTGAFRPDAPSWAWE
                     VHVFSSNELNAWCMAGGKMAIYTGLIQRLALSDDEIAAVMGHEIAHALREHARERVSK
                     SMATGLGISVAGALLGVGQLGQDLMSQVAKVTFELPNSREHETEADRMGVELAARAGY
                     DPRAAVTLWNKMAGQSAGAPPQWLSTHPSHATRQKDLAEYAARVMPLYQGARR"
     gene            13205..>14460
                     /gene="leuC"
                     /locus_tag="P5537_11760"
     CDS             13205..>14460
                     /gene="leuC"
                     /locus_tag="P5537_11760"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HRV78761.1"
                     /translation="MQAQTLYEKLWSSHVVHQEADGTALIYIDRHLVHEVTSPQAFEG
                     LKLAGRKPWRIGSIVATADHNTPTDHWDLGIQDPVSRQQVETLDANIREVGSLAYFPF
                     KDARQGIVHVIGPENGATLPGMTVVCGDSHTSTHGAFGCLAHGIGTSEVEHVLATQCL
                     LQKKSKTMLVRVDGQLGRGVTAKDVVLAIIGRIGTAGGTGYAMEFGGSAIRALSMEGR
                     MTICNMAIEAGARAGMVGVDETTIEYLKDRPFSPKGEQWEQAVDYWRSLHSDEGAEFD
                     KVVELKAEDILPQVTWGTSPEMVTTVDGRVPDPAAVTDPVRREGIERALKYMGLAANT
                     PITDIPVDQVFIGSCTNSRIEDLREAAAVAKGRTKAASVKRVLVVPGSGLVKRQAEAE
                     GLHEVFLAAGFEWREPGCSMCLAMNA"
BASE COUNT         2290 a         4873 c         4953 g         2344 t
ORIGIN      
        1 ttcgagctga tggcgtcgat gatcgagtac atcgagatgg tccccgagaa ggtgcaccac
       61 cccaaggagg acacctatct cttcgcccgc ctgcgcgagc gcagcgccga ggcgctgccg
      121 atcatcgagc gcctcgaggc cgagcaccgc gagggcgatg cgcgcatcgc cgccttgcgc
      181 agcgcgctcg aggcctaccg gcgcgagggc gaagccggcc tggcgggctt ccaggccgcg
      241 ctcaagacct acatcgagca tgagtggcag cacatgaaca ccgaggagca cctgatcttc
      301 ccgctcgcca ggaagcacct gagcgcggag gactgggcgc agatcgatgc cgccttcctc
      361 gccaacgaca acccctggca gggtccggcg ggcaagtacg cggcgctgtt cacccgcatc
      421 gtcaacaccg ccccggcgcc ggtcgggctg ggcggcggct gagcgcacgc tccggcggcg
      481 ttggccgcag gcgccgcggc gcctggcatc cctcgccgcc ccaggctctc cctccccgaa
      541 atcgagcagt tcgtcgtggt tgccttctgc gcgcccgcgc agaggtgatt tcgggtttgg
      601 cccgcttcgg cgggcctttt tttgtgctcg ctcgccgcga cgtggcggcg ggccggcggc
      661 ggctcagtgg ctggcggtgg aggcgttgtc gaggcggacc gactgcagcg tcaggcggat
      721 gtgttcgccg agcaggcggg tggcggtgtc ggcgtcgcgc gccatcgcgg cctcgaacag
      781 ggcggcgtgc tcgtcgtgca gccggcgcgt gccttcgctg cggcgcagcg agaggtggcg
      841 gtagcgctcg gcctggtggt agaggatgga caggaagtgc ttggtccagc gcgaggggca
      901 ggcggcgatc agcacctcgt ggaagatgcg gttgcgctct tcccactgct cgcggttgtt
      961 gccctcggcg agcttctcct ctgcgcgggt gaggcggtgg aaggcggcgg tgaggtcggc
     1021 ctcccaggcg tcgtcgccga gcgcgatcga ctggcgcagc gcgctgcact cgagcatcac
     1081 acgcgtctcg gtgatgtcgg cgaggtcctc gagcgaaacc ggggcgacgc gaaagccgcg
     1141 ctggccctgc gacaccacca gtgcatcgga ggtgagcagc gagagcgcct cgcgcagcgt
     1201 cgccccgccg acgccgtagt cgttcttgat gtgctcgatg cgcagcttct cgcccggcga
     1261 caggcggccc tcgatgatgt tgcggcgcag gctgcggtag gcggcctcaa ccagcgtctt
     1321 cggttcggcg acctcggttt cttggcggac tgcgtagggg ggcgaggtgt ggagcatgat
     1381 gtgcgcgacg actgcgagga agggaggaaa ggcgaggccg gtgaagaccc gtttaatgta
     1441 gccgcagcct cgacggctca caagaaaaat atcgagaaac gacctgaaat acggctcgtg
     1501 cgcagcgctt cggcgtagtc gccgagcatc gagaaatgct cgggcggcgg gtcctgcaag
     1561 ccaccccgct gcgccgccgc ttcatgctgg cacccccctg cggaatccgc taaagtctcc
     1621 cgcgcatacg cagcggtatg gagaccgtcg tccggcggcc gctgtgtcga ccaaaatcct
     1681 gttcggagag cgaaggcgat gagtatcggc aagatcggag tggtgggtgc gggcacgatg
     1741 gggaacggca tcacccaggc gttcgcggtc gcggggcgcg cggtggtgat gatggacatc
     1801 ggcgaggcgc aggtgcagcg cgggctcgcg accatctcgg ccagcctcga ccgcctgatc
     1861 aagaaggaca ggatgagcgc ggagcagaag gccgccgcaa tggcctgcat caccacggtg
     1921 acctcgctcg aggcgctcgc cgactgcgac ctcgtgatcg aggcggcgac cgagaacgtc
     1981 gatctcaagc tgcgcatctt cgccgacctc gaccgcatcg tgaagcccga ggcgatcctc
     2041 gccagcaaca cctcgtcgat ctccatcacc cgcctggccg ccggcacgca acgccccggc
     2101 caggtgatcg gcatgcactt cttcaacccg gtgccggtga tggcgctggt cgagctgatc
     2161 aacggcctgc agacctcggc ggcgacctac acggcggtcg aggacgtcgc gaaggcgatc
     2221 ggcaagaccc cgatcaaggt caagaacagc ccgggcttcg tggtcaaccg catgctgtgc
     2281 ccgatgatca acgaggccgt gttcgcgctc ggcgagggcc tggcgaccgc ggccgagatc
     2341 gacgaggcga tgaagctggg ctgcaaccac ccgatcggcc cgctcgcgct gtgcgacctt
     2401 atcggcctcg acgtcgagct ggcggtgatg caggtcctct acgagggcac caaggacccc
     2461 aagtaccgcc cggcgccgct gctggtcgag atgctcgagg cgggctacct cggccgcaag
     2521 agcggcaagg gcttctacga ctacaagtaa gcgcaggcgc cggccgcgcg tcgcgcggcg
     2581 gggccctacg aaaaaaacgc cacctgcgag gtggcgtttt gctgtcgggc gcgcgctcag
     2641 ccgcggccgg tgcgcatcgc gtcgaagaac tcggcgttgc tcttggtggc cttgaccttg
     2701 tcgaggagga attccatcgc gtcgatgtcg tccatgccgt agagcagctt gcgcaggatc
     2761 cacaccttct gcagcacgtc ggacttgagc aggagctcct cgcggcgggt gccggagcgg
     2821 ttgacgttga tcgccggata gacgcgcttc tccgccatgc ggcggtcgag gtggagctcc
     2881 atgttgccgg tgcccttgaa ttcctcgtag atcacgtcgt ccatgcggct gccggtgtcg
     2941 accagcgtgg tggcgatgat ggtcagcgag ccgccttcct cgatgttgcg cgccgcgccg
     3001 aagaagcgct tgggcttctg cagcgcgttg gcgtcgacac caccggtgag caccttgccc
     3061 gaggccggca ccacggtgtt gtaggcgcgc gccaggcggg tcagcgagtc gagcaggatc
     3121 accacgtcgt acttgtgctc ggtcaggcgc ttggccttct cgatcaccat ctcggcgacc
     3181 tgcacgtgac gggtggcggg ctcgtcgaag gtggaggcca cgacctcgcc cttcaccgag
     3241 cgcagcatct cggtcacttc ttccgggcgc tcgtcgatca gcagcacgat cagcttgacg
     3301 tccggatggt tggccgtgat cgcgtgcgcg atgtgctgca gcatgaccgt cttgccgctc
     3361 ttgggcgggg cgacgagcag gccgcgctgg cctttgccga tcggcgcgat catgtcgatg
     3421 atgcggctgg tgatgttctc ctcgccgcgg acctcgcgct cgagcttcag gcactcctgc
     3481 gggtgcaggg gcgtgaggtt ctcgaacagg atcttggtct tgcactcttc cggcggacgc
     3541 ccgttgatct tgtcgagctt ggtcagcgcg aaatagcgct cgccgtcctt gggcgtgcgg
     3601 atctcgccct cgatggtgtc gccggtgcgc aggttgaagc gccggatctg cgagggcgac
     3661 acgtagatgt cgtcggttcc cgcgagatac gaggtgtcgg gggagcgcag gaagccgaag
     3721 ccgtcaggca gcacttcgag tgcgccatcg ccacagatcg gttcgcccct gcgggcacgg
     3781 ttgcgcagca gcgcgaagac gagttcctgc ttgcgcagcc tgttcgcgcc ctcgacgccg
     3841 gcgtccatcg ccatctgcag cagctggctg acgtgcaggg ccttgagttc ggacaggtgg
     3901 agcgcgggcg cgtcggggtc gcgcggcgtg gaagagcctt cctcgccgcc gttctcgacg
     3961 tcgaacagat cgtcttcggt ctgcggattc tggggggaat tgccgtcccg gttgcgcgcg
     4021 ccgcggcgac gggcgcgcga ggaaccgcgg gagcgggccg gagcctggtc cggcttagat
     4081 gttgctgtca atgaaggcgg tcagttgaga tttggaaagg gcgcccactt tggtcgcctc
     4141 gacgttgccg cccttgaaca gcatcagcgt cggaatgccg cggatgccgt acttggcggg
     4201 cgtgtcctgg ttgtcgtcga tgttgagctt ggcgaccttg agcttgcccg catagtcctt
     4261 ggcgacgtcg tccaggatcg gcgcgatcat cttgcagggg ccgcaccact cggcccagta
     4321 atcgaccagg acaggggtct gggactgcag cacttcgctg tcgaagttgc cgtcggtcac
     4381 atggtggatg tgctcgctca tgattcctca ctaaggctgg caggggtggt gacgaaggcg
     4441 aaagccctcg ttgccgggta aaaggtgctg cggagtaatg cgaacgggta ctgcgtgcgg
     4501 gaaggggcga atcgcctgcg atctcgccgc gagcgcgaaa cgctgcggcg atgcacgacg
     4561 atccagcgga aggagaggcc ttccgtaaag aaatttttcc gaaacttatg cgatgccgag
     4621 ggcgccgtca aggaaatcgc agcccgcggt cgcgcatgtg ccggctcgcc gtggcaaaaa
     4681 agcaaacggc tggtctatat tgtgcctcct tcggccagcc gcagcgggtg gcggccgttc
     4741 ttgcctggag aatgtagatg acctacgtcg ttaccgagcg ctgcatacgc tgcaaataca
     4801 ccgactgcgt ggacgtctgt ccggtcgact gcttccgaga gggccccaac ttcctcgtca
     4861 tcgatccgga ggagtgcatc gactgtaccc tgtgcgtggc cgagtgcccg gtcgaggcga
     4921 tctactccga ggacgacgtg cccgacgatc agaaggaata catcgcgctc aacgccgaac
     4981 tggcgaagca gtggaagccg atcgtcgagc gcaaggaccc gctgccggac gccgaccact
     5041 gggcccgcat caagggcaag ctcggcgagc tgaagcgctg aacgcccgcc gcggccggct
     5101 ttgcgagcac gcggcgatgc actaagatgg tgagcgtcat caaacctgtt agcgaaacgg
     5161 cacggagacc gacatgctgg tgagcgagat tctcgcgatc aagggcaagg tgttattcac
     5221 catcggcccc aaccgaccca tcgccgaggc ggtcgagatc atgaacgagc aggacgtcgg
     5281 ctcgctggtc gtgttctcgc gtggcgagat ggtcggcatg ctcaccttcc gccaggtgct
     5341 gcaggcggtg cagcgcggcg gggcggactg gcaggcgctg caggtcgagg aggtcatgct
     5401 gcgcgagccg cgcgcggccg cacccgacat ggagatggac gagctgcgcc ggctgatggt
     5461 cgagcaccac cagcgctacc tcccggtgat ggacggcacc acgctgctcg gcgtggtcag
     5521 cttccatgac gtcgccaagg cggtgctcga ggagcagagc ttcgagaacc gcatgctcaa
     5581 gaactacatc cgcaactggc ccgcgggcga gggcgaagaa taagcggtac ggccgggttg
     5641 caagcccggc ggcggcgggc agtccgccgc gcctccagga gcgggtccag cccgctccgc
     5701 cgacacccac accaagatcg ggtgcggcat ggttggaatg aacggacggg ccgcttgccc
     5761 gtccgacgcc ttgggagggc ggagccgggg tgccatggcg gccctccggc agtatttcca
     5821 gcaagaggag gagaccatgg aaaaaatctg gctgaagagc taccccccgg gcattcccgc
     5881 ggaaatcgac gtcgacgcgt tccgctccct gggcgacctg ttcgagcgca gtgtggcgcg
     5941 cttcgcggac aagcctgcct atcactgcat ggggaagtcg atcacctacg ccgagctcga
     6001 cgcgctcagc gcgcgcttcg gtgcctggct gcagagcgag ctgaagctcc cggcaggcgg
     6061 gcgtgtcgcg ctgatgatgc ccaacgtgct gcagtatccg atcgcgctct tcggcacgct
     6121 gcgcgccggc tacacggtcg tcaacgtcaa tccgctctat accgcccgcg agctcgagca
     6181 ccagctcaag gattccggcg ccgaggcgat cgtgatcctg gagaacttcg cccacacgct
     6241 cgagcacgtg cgtgcgcagg tgtcggtgcg ccacatcgtg gtcaccagcc tgggcgagat
     6301 gctcggcctg gtgaagggca cgatcgtcga tttcgtcgtg cgcaaggtgc gcaagctggt
     6361 cccggcgtgg cggctcgacg gccacgtgcg cttttccacg gccttgcagc gcggcgcggc
     6421 gcacaagctg cagccggcga cggtcggcca cgatgacatc gccttcctgc aatacaccgg
     6481 cggcacgacc ggggtggcca agggcgcgat gctcacccac cgcaacatca tcgccaacct
     6541 gcagcaggcg cacgcctgga tcgctcccta cgtgggcgag ggcagggaaa tcatcatcac
     6601 cgcgctgccg ctgtaccaca tcttctcgct caccgcgaac tgcctcacct tcctgaagat
     6661 cggcgccaag aacgtgctga tccccaatcc gcgcgacatc ccgggcttca tcaaggagct
     6721 cggccagcac cgcttcaccg ccatcaccgg cgtcaacaca ctgttcaacg cgctgctcaa
     6781 caaccccgag ttcgccaggc tcgacttctc gacgctgcgc gtgagcctag gcggcggcat
     6841 ggcggtgcag caggtggtcg ccgagaagtg gaagaaggtc accggggtgt cgctggtcga
     6901 ggcctatggc ctcaccgaga cttcgcccgc ggtgacgatc aacccgctcg acatcgccga
     6961 gttcaaccac tcgatcggtc tgccggtgtc ctccaccgag atcagcatcc gcgacgatgc
     7021 cggcaacgag gtgccgctcg gccagcgcgg cgagctgtgc gtgcgtggtc cgcaggtcac
     7081 gccgggctac tggcggcgcc ccgaggagac cgcgcgcgtg ttcacgcacg acggcttcct
     7141 gcgcactggc gacatcgcca cggttgacga gcacggcttc gtgcgcctgg tcgatcgcaa
     7201 gaaggacatg atcctggtgt cgggcttcaa cgtgtatccg aacgaggtcg aggacgtggt
     7261 cgccagccat ccgggtgtgc tcgaggtcgc cgcggtcggc gtgcccgacg agcgcagcgg
     7321 cgaggcggtg aagatcttcg tggtgcgcaa ggatgccggc ctgacggccg aggccctggt
     7381 cgccttctgc cgcgagaacc tcaccggcta caaggtgccg caccacgtcg agttccgcga
     7441 cgaacttccc aagagcaacg tcggcaagat cctgcgccgc gagttgcggc cgaagtgagt
     7501 gcgcatgcgg ggagggcgcc ggagcctccc cgcgcgacac cgggtgtgga cgtgcgcacc
     7561 ggggccacgc gagattcttc ttgtgcggtg cagcttttcg tgattaaact catggccatg
     7621 tcgttttcga gcagatccgt ttcaatgtcc cttttccgcc cttcctcgct gctgtcgctg
     7681 gtactcgtag tacgcgtagt aggcgtaggc acgcgcgcga cgtaaaggga ccggacactc
     7741 gagactcagg aaacccagac ccccgtcggc gcgcaagccc ggcgggggtc ttgcttttgt
     7801 gcccgccggt ccggccgtcg aacccgaagc caaggagagc aacatgatgc aaatgaccgg
     7861 cgcgcaattg atggtgcgcc ttctcgagcg ccagggcgtg cgcaccgtcg ccggcattcc
     7921 cggcggcgcg atcctgccct tctacgatgc cttgtcgggc agcgagcaga tccaccacgt
     7981 gctcgcccgt cacgagcagg gcgcgggctt catcgcccag ggcatggcgc gcgtgtcggg
     8041 cgtgccgcag gtgtgcatcg cctcgagcgg gccgggtgcg accaacctcg tcaccgcgat
     8101 cgccgacgcc tgcctggatt ccatcccgat ggtcgtcatc accggccagg tgccgcaggc
     8161 gatgatcggc accgacgcct tccaggaggt cgacatctac ggcatcacgg tgcccatcac
     8221 caagcacaac ttcctcgtgc gttcggcgcg ggatctgctc gaggtggttc cggacgcctt
     8281 ccgcatcgcc atgtccggcc gccccggccc ggtgctgatc gacgtgccca aggacgtgca
     8341 gaaccagctc gtcgaggtcg ccgactttcc cgccccggcg gtcgccgatc cggcccctca
     8401 gctcgacctg gcggcggtgg agcttgcggc gaagatgatc aacgaggccg agcagccggt
     8461 gctctatctc ggcggcgggg tgatcaactc cggcgccgcg ccactggcgg cccagctcgc
     8521 cgagcaggcc gggctgccca ccacgatgac gctgatggcg ctcggcgcga tgccgatgga
     8581 ccacccgctg tcgatcggca tgctcggcat gcacggtgcg cgctacacca acttcgtgct
     8641 ggaggaggcc gacctgctgg tgtgcgtggg cgcgcgcttc gacgaccgtg cgatcggtcg
     8701 cgccgcgcag ttctgcccga acgcgaagat cgtgcacatc gacatcgacc gctccgagct
     8761 gcacaagatc aagagcgccc atgtcgccat ccacgccaac gtgaaatgcg cgctcgaggc
     8821 cctgctgccg cgtgtgcagg ccacgctgcg caagcgctgg ctgtcgcatg tggacagcct
     8881 gaagacgcgc ttcccgatgc agttccccgg tcaggacgac ccgcgcaccc actacgggct
     8941 catccacgcg gtggcggctg cgctcgacga ccgcgccatc gtcgccaccg acgtcggcca
     9001 gcaccagatg tgggtggcgc aggcctatcc cttccgccgg ccgcgccagt ggctgacctc
     9061 gggcggcctg ggcacgatgg gcttcggcct gccgaccgcg atcggcgccg ccctcgccga
     9121 gccggaccgc acggtggtct gcttcaccgg cgacggcagc ttcaagatga acatccagga
     9181 gctcgcgacg ctggccgagg agggcctgaa cgtcaagatc gtgctgatga acaacaacgc
     9241 gctcggtctg gtgtaccagc agcagacgct gttctacggc cagcgcctgt tcgcctcgaa
     9301 gtaccgcacc gagcccgact tcgtgaagat cgccgagggc ttcggcgtgc cggcggtgga
     9361 tctcgacctc gccgacaatc cgcgcgccgc gctcgccgag gcgctgcatc gtcccggtcc
     9421 gtgcctgatc cacgcgacca tcgaccgcga acaattcgtc tatcccatgg tgccgccggg
     9481 tgccgccaac accgagatga tcggaggctg atgatgatcg aacaggttgc cgacccgctg
     9541 ccgcaagccg gctacgccaa ggtcgttctg gagctggatg tgaacaacca ccccggggtg
     9601 atgagccaca tctgcaatct cttcgcgcgc cgcgcgttca acgtcgaggg catcctgtgc
     9661 atgccggtgt ccgacggcaa gcgctcgcgc atctggctgc tggtgttcga ggaccagcgt
     9721 ctcgagcaga tggtgcgcca gctcgagaag ctcgaggacg tgctcaacgt tcgccgccac
     9781 ggcgccgagc acgaggtctt cgagcgcctg gagggcttct tccactgagt gtcggcgcct
     9841 cggcgcccaa gcagaagggg acggcacgcg tgctagactc gcgtcccgtc cccgtttcgt
     9901 catcgcgatc aggcaggcaa cccatgtccg gcaacaccct cggcacgctc ttcaccgtca
     9961 cctccttcgg cgaatcccac ggcccggcga tcggctgcat cgtcgacggc tgcccgccgg
    10021 gactggcgct ctgcgaggcc gacatccagg ccgagctcga ccgccgcaag ccgggcacct
    10081 cgcgccacgt cacccagcgc cgcgagcccg acacggtcga gatcctctcc ggcgtgttcg
    10141 agggcgtcac caccggcacg ccgatctcgc tgctgatccg caaccaggac cagcgcagca
    10201 aggactacgg caacatcgcc gacaccttcc gtcccggcca cgccgactac gcctatctgc
    10261 agaagtacgg cctgcgcgac caccgcggcg gcgggcgctc gtcggcgcgc gagaccgcgg
    10321 tgcgcgtggc cgccggcgcg atcgcgaaga agtggctgaa ggagcgccac ggcatcgtga
    10381 tccgcgcctg catgggcgcg ctcggcccgc tcgagatccc cttcgtgtcc tgggacgagg
    10441 tcgacggcaa ccccttcttc gcccccaacg ccgcgatcgt gcccgagctc gaggcctaca
    10501 tggatgcgct gcgcaagtcg ggcgactcga tcggcgcgcg catcgacgtc gtcgccagcg
    10561 gtgtgccggt gggctggggc gagccggtgt acgggcgcct cgatgccgac atcgcctacg
    10621 cgatgatggg catcaacgcg gtcaagggcg tggagatcgg cgccggcttc aaggcggtgg
    10681 cgcagcgcgg caccgagcac ggcgacgaga tgaccccgga gggcttcctg tccaaccacg
    10741 ctggcggcgt gctcggcggc atctccaccg ggcaggacat cctcgccagc atcgcgatca
    10801 agccgacctc gagcctgcgc ctcgagcgcc gctcgatcga ccgcgccggc aacccggtca
    10861 tggtcgccac cgaaggccgc cacgatccct gcgtcggcat ccgcgccacg ccgatcgccg
    10921 agtccatgct cgcgctggtg ctgatcgacc acgcgctgcg ccaccgcgca cagtgcggcg
    10981 acgtgcgcac cgacaccccg cgcatccccg cgctcgcgcc cgaggggcgc cagcgcctgc
    11041 cttcgccgcg ctgaggcgat gcgggcaggg tggggcggcg cggtgtgccg cccgggcgca
    11101 ggggctggag cgggttccta cgcggagcgg gcgcgatgat tccctactgg cgcctgtcgg
    11161 cctactactt cttctacttc gccttcgtcg gcgcgttctc gccctacttc acgctctacc
    11221 tgcagtcgat cgcgctgtcg gccaccgaca tcgcgctgct gatgtcgctg atgcagctga
    11281 tgcgcgtgct ggcgcccaac ctgtggggct ggctcgcgga acgcctgggg atgcgcatcg
    11341 cgatcgtgcg cttgtcggcg ctcgccagcc tggcgggctt ctcggtgttc ttcctcacca
    11401 ccgagttcgc cgggctgttc gccgcgatgg cgctgatggc cttcttctgg agcgcggtgc
    11461 tgccgctgat cgagggattg gccttcgccc acctcggcga gcaggcgcac cgctacggca
    11521 gcatccgcgt gtggggttcg gtcggcttca tcgtggccgt gctcgccctc ggccactcgc
    11581 tcgaccgcct gccgatcgag gcggtgctgt gggtcaccgt atccatcctc gccggcatcg
    11641 tgctgtgcag cttcatcgtc cccgaggccc cgcgcccgcc gccgcagcgc gacgccgcga
    11701 gcttcggcga caccctgcgc cgccccgagg tgcaggcgct gctcggggcc tgcttcctga
    11761 tgtcggcggc gcacggcgcg ctctacgtgt tctattccat ctatctggtc gacatcggct
    11821 acgacaaggg cctggtgggc tggatgtgga ccctgggcgt gctcgccgag atcgtcgtct
    11881 tcatgtggat gccgcggctg acccggcgct tctcgctgcg cgcgatcctg ctgttctcct
    11941 tcgcgtgcgc ggtggggcgc ttcctgatga tcggctgggg cgcgcacagc ctggtgttgc
    12001 tgctgctcgc gcaggtgctg cacggcgcga ccttcggcgc ctaccatgcg gcggcgatcg
    12061 cggtggtcaa cgagtggttc ccgggccgcc tgcagtcgcg cggtcaggcg ctctacggca
    12121 gcatctcctt cggtgccggc ggcatgctgg gcggtttgct gagcggttac acctgggagg
    12181 gcatcgggcc ggcgtggacg tatacgatcg gttccggctt cgcgctcgcc ggcctgctgt
    12241 ggttgctgct gggctggaag agggaaccgg gcgccgcgga gggactccac gaaccgagga
    12301 ggtaatcgac ccatgcaatc catcctgaag atcgccctgc cggtgctgct cgccggcacc
    12361 atcaccaccg cctgccagac cgtgcagacc acgcacggcg gtgcggtggg cgtgcagcgc
    12421 tcgcagctga tgatggtctc ggcccaggag gtcgagcagg cctcgagcca gcaataccag
    12481 cagatggtcg cggaagcgcg gcgcaagaat gcgctcgacc gcgacccggc caccgtgcag
    12541 cgcgtgcgcc gcatcgtctc gcgcctgacc gcgcagaccg gcgccttccg gcccgacgcg
    12601 ccgtcctggg cctgggaggt gcacgtgttc agctcgaacg aactcaacgc ctggtgcatg
    12661 gccggcggca agatggcgat ctacaccggg ctgatccagc gcctcgcgct gagcgacgac
    12721 gagatcgccg cggtgatggg ccacgagatc gcgcacgcgc tgcgcgagca cgcgcgcgag
    12781 cgggtgtcga agtcgatggc gaccgggctg gggatctcgg tcgccggcgc cctgctcggc
    12841 gtgggccaac tcggccagga cctcatgagc caggtcgcca aggtcacctt cgaactcccc
    12901 aactcgcgcg agcacgagac cgaggccgac cgcatgggcg tggagctcgc cgcgcgcgcc
    12961 ggctacgacc cgcgcgccgc ggtgacgctg tggaacaaga tggcgggcca gtcggccggg
    13021 gcgccgccgc agtggctgtc cacccacccc tcgcacgcga cgcggcagaa ggacctggcc
    13081 gagtacgccg cgcgcgtgat gccgctctac cagggggcac ggcgctgagg accgggcgcg
    13141 cctacacagt tttgcaggct ttgtgaaata atcgatttct ttttcagacg cggaaccatc
    13201 cgggatgcaa gctcaaacgc tgtacgaaaa gctctggtcc agtcacgtcg tccaccagga
    13261 ggccgacggc acggcgctga tctacatcga tcggcacctg gtgcatgaag tgaccagccc
    13321 gcaggccttc gaggggctca agctcgccgg gcgcaagccg tggcgcatcg gctccatcgt
    13381 cgccaccgcc gaccacaaca cgcctaccga ccactgggac ctgggcatcc aggatccggt
    13441 gtcgcgccag caggtcgaga cgctcgacgc caacatccgc gaggtcggct cgctggccta
    13501 cttcccgttc aaggatgcgc gccagggcat cgtgcatgtc atcggtccgg agaacggcgc
    13561 cacgctgccc ggcatgaccg tggtctgcgg cgactcgcac acctccacgc acggtgcctt
    13621 cggctgtctg gcgcacggca tcggcacctc cgaggtcgag cacgtgctcg ccacccagtg
    13681 cctgctgcag aagaagtcga agaccatgct ggtcagggtc gacggtcagc tcggccgcgg
    13741 cgtcaccgcc aaggacgtcg tgctcgccat catcggcagg atcggcactg ctggcggcac
    13801 cggctacgcg atggagttcg gcggcagcgc catccgtgcg ctgtcgatgg aaggccgcat
    13861 gacgatctgc aacatggcga tcgaggcggg cgcgcgcgcg ggaatggtcg gcgtggacga
    13921 gaccaccatc gaatacctga aggaccgccc cttctcgccc aagggcgagc agtgggagca
    13981 ggcggtcgac tactggcgca gcctgcacag cgacgagggc gccgagttcg acaaggtcgt
    14041 cgagctgaag gccgaggaca tcctgccgca ggtcacctgg ggcacctcgc ccgagatggt
    14101 caccacggtc gacggccgcg tgcccgatcc cgccgccgtc accgacccgg tgcgccgcga
    14161 gggcatcgag cgcgcgctca agtacatggg cctcgcggcc aacaccccga tcaccgacat
    14221 cccggtcgac caggtcttca tcggttcgtg caccaactcg cgcatcgagg acctgcgcga
    14281 ggccgccgcg gtggccaagg gccgcacgaa ggccgccagc gtcaagcgcg tgctggtggt
    14341 gccgggctcg ggcctggtca agcgccaggc cgaggccgag ggcctgcacg aggtcttcct
    14401 cgccgccggc ttcgagtggc gcgagccggg ctgttcgatg tgcctggcga tgaacgccga
//
LOCUS       DAOTIN010000080        14326 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_5083_length_14326_cov_8.732394, whole genome shotgun sequence.
ACCESSION   DAOTIN010000080 DAOTIN010000000
VERSION     DAOTIN010000080.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 14326)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 14326)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14326
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5083_length_14326_cov_8.732394"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(164..673)
                     /locus_tag="P5537_11765"
     CDS             complement(164..673)
                     /locus_tag="P5537_11765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate lyase"
                     /protein_id="HRV78762.1"
                     /translation="MTSHPALTLEIKPLTREAFAPFGEVVEASDAAQHFTINAGNTER
                     YHDLAHIEPGPDGRVIVSIFRGQPRSLPFTVQMMERHPLASQAFIPMSGRPYLVVVAP
                     AGEPPGVEDLKVFLARADQGVNYATGVWHHPLLALEGVCDFLVVDRSGPGHNCDEVQL
                     DRHGVIEER"
     gene            complement(756..1802)
                     /gene="alc"
                     /locus_tag="P5537_11770"
     CDS             complement(756..1802)
                     /gene="alc"
                     /locus_tag="P5537_11770"
                     /EC_number="3.5.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004037 - allantoicase activity [Evidence
                     IEA];
                     GO_process: GO:0000256 - allantoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="allantoicase"
                     /protein_id="HRV78763.1"
                     /translation="MASHTPGAPVFAPAAELPDWALRSVDLANPRLGAKALAASDDFF
                     AEVTRMLNPEPAQFVPGKFDTNGKWMDGWESRRKRVAGHDWALVRLGVKGVIRGFDVD
                     TSHFTGNYPPAVSIEACVSETDEVEALQAATWTEILPASPMGPNRHHLLECTSTAAWT
                     HLRVNMYPDGGIARLRVYGRPVSTLATTAAGALVDLVAMENGGRAVSWNDASFGSSAS
                     ALLLPGRGMNMGDGWETRRRREPGNDWCVLELGTPGTVERIEVDTAFFKGNYPDRCSV
                     QAAYVTGGTDRSITTQSMFWQTLLPEQKLEMDAIHTFTDEVARLGPITHVRFNIFPDG
                     GVSRLRLWGKVETK"
     gene            complement(1824..2756)
                     /gene="puuE"
                     /locus_tag="P5537_11775"
     CDS             complement(1824..2756)
                     /gene="puuE"
                     /locus_tag="P5537_11775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0000256 - allantoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="allantoinase PuuE"
                     /protein_id="HRV78764.1"
                     /translation="MTSHSTYPRDLVGYGRNPPHADWPGRARVAVQFVLNYEEGGENC
                     VLHGDAGSEQFLSELFNAASYPERHLSMEGIYEYGARVGVWRFLREFERRGLPMTIFG
                     VSMALERHPELTAAFKELGHEIACHGWRWIHYQNTPEEVEREHMKIGMELIERLTGER
                     ALGWYTGRDSPNTRRLVADYGGFLYDSDYYGDDLPFWTEVQKTDGETVPHLVVPYTLD
                     TNDMRFALPQGFSHGDEFFEYLRDAFDVMYAEGEERPAMMSVGMHCRLLGRPGRFRAL
                     QRFLDHIEKHDRVWVCRRVDVARHWIERHPYAPK"
     gene            complement(2774..3328)
                     /gene="uraD"
                     /locus_tag="P5537_11780"
     CDS             complement(2774..3328)
                     /gene="uraD"
                     /locus_tag="P5537_11780"
                     /EC_number="4.1.1.97"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019628 - urate catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline
                     decarboxylase"
                     /protein_id="HRV78765.1"
                     /translation="MSTSKTATAPDRTTAALTELSRLPQDAFVARLDGIFEHSPWIAE
                     RAWSAGPFTSIDALHAAMCLVVDTADPAEQLGLICAHPELAGKEAEAGTLTTASTGEQ
                     RGAGLDQCSKEELERLRRLNQDYRARFGFPFVVAVKGLTRHQIMDRVEARLANARDTE
                     FRTCLNEIGRIARFRLDALFGAGA"
     gene            complement(3357..4550)
                     /locus_tag="P5537_11785"
     CDS             complement(3357..4550)
                     /locus_tag="P5537_11785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urate hydroxylase PuuD"
                     /protein_id="HRV78766.1"
                     /translation="MEAYLLDWANLLVRWLHLIAGIAWIGASFYFVMLDNSLKPPKKP
                     EDGARGVFGELWAVHGGGFYHSQKYLTGPKGEPLTQDLHWSKWEAYTTWLSGMGMMAI
                     IYWIGASSYLIDSSVMALSPAAAVGISIAFLVAGWVVYDVLCRNMVGKDGLLAAIVFV
                     LVMVANYVLHQVFSARGAYIHVGAMLGTMMAANVFFHIMPGQRRMVAQIHAGEKVDPR
                     PGIIGKQRSVHNTYFTLPVLFIMISNHYPMTYANANGWLVLGVLMLAGVLIRQFFVLR
                     HRGQVKWWLPAAGVALIALLMVLMAPKQVDAGGEKVSFATVKAIMAQRCIACHAEKPT
                     FEGFAQAPKGVMLETSEQIAANAVMSAQTVASGYMPLGNLTQITDAEREQIAIWFAQG
                     ARTAD"
     gene            complement(4588..4938)
                     /gene="uraH"
                     /locus_tag="P5537_11790"
     CDS             complement(4588..4938)
                     /gene="uraH"
                     /locus_tag="P5537_11790"
                     /EC_number="3.5.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019628 - urate catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyisourate hydrolase"
                     /protein_id="HRV78767.1"
                     /translation="MGRLTTHVLDTAHGKPGVGIAVTVYRLDGERREVARTVTNHDGR
                     CDRPLLEGAALEAGRYEIVFGAGDYFRALGLNLPEPLFVDEVALRFGIANVDQHYHVP
                     LLVSPWSYSTYRGS"
     gene            5120..>5989
                     /locus_tag="P5537_11795"
     CDS             5120..>5989
                     /locus_tag="P5537_11795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001216 - DNA-binding transcription
                     activator activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HRV78768.1"
                     /translation="MSLRRSDDPLDTYLLRVFVLLITERSVSRTALRLNQSQPAVSAA
                     LKRLREILGDPLLVREKGGMVPTERALALMSHAKGALAEIDRMTDAPESFEPNSTRHE
                     FRVGSPDYLAPVFVASVAERFRREAPQARLSLHALGPSFDFERSLAEGDLDVVIGNWP
                     EPPHRMHLSMLLEDEIVCLVAASHPCAKKGMSVEDYMRAAHVVPMPYSISQRGVIDSV
                     LASMRINRDERVAVQSFTAAPYLLQGTDLVFTTTRHFAQFYAQLLPLAIIPSPIAFPP
                     MRFYQLWHERNHHS"
     assembly_gap    5990..6089
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(6095..6568)
                     /locus_tag="P5537_11800"
     CDS             complement(6095..6568)
                     /locus_tag="P5537_11800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HRV78769.1"
                     /translation="MSYEIRSILYASDLTPRSPAVFRHAVGLAMKFNAKLHAVTVTLP
                     SSSLPYEEFLSEEKMDEIKLAGHKKAEALLRHRIDVFAEANPELDVKSVLASVRALEG
                     DASRRILDVAKHVLADVIVMGSRGHSTIGELLLGSVAHKVTMKADIPVMLVPIDR"
     gene            6845..7555
                     /locus_tag="P5537_11805"
     CDS             6845..7555
                     /locus_tag="P5537_11805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase N-terminal
                     domain-containing protein"
                     /protein_id="HRV78770.1"
                     /translation="MIDLYTAATPNGHKVSIALEELGLPYSLRVLDLSANEQKEPWFL
                     AINPNGRIPAIVDHDEGDFAVFESGAILIYLAEKTGRLMPQDAKGRSRVLQWLMFQMG
                     GVGPMMGQANVFFRYFPEKLQPAIDRYQGEVRRLFRVLDGHLARNEYLAGDYSIADIA
                     NWAWVRTHNWSGVAIDDLPNLARWRDRIRARPAVQRGIEMPPSSLDLEGDREERAKAF
                     SDKVRNMVETGQSRSGGV"
     gene            7600..8226
                     /locus_tag="P5537_11810"
     CDS             7600..8226
                     /locus_tag="P5537_11810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase family protein"
                     /protein_id="HRV78771.1"
                     /translation="MKLYVSPRAPNPRRVQMFIAEKGIRGIEEVAVDLVKGEHRSSDH
                     RARSPLAKVPVLELDDGRYLGETRAICSYLEGLYPEPNLMGERFEERAFIEMTDRRVE
                     LYLFGGIMNCIRHTHPGLAPLEQPQFEDFGRSQGEKVREVARWLDEELGRQPFVAGER
                     FTIADITAFCAIEFARGLMKFKPGAEGMANLQDWRDRIVERPSARTGG"
     gene            8451..12038
                     /locus_tag="P5537_11815"
     CDS             8451..12038
                     /locus_tag="P5537_11815"
                     /inference="COORDINATES: protein motif:HMM:NF019974.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HRV78772.1"
                     /translation="MSIRRLFLVVFGLLVLLIGVTFIPTLSAYRTQVTHLRAIGEANV
                     ITGAVQRLMSALAAERGLGVLLLSASSGREVLRARLLEARELSDYEYVRFRSLAVPRL
                     ENVADPTGLMVYADIARDFAALKALRSAMDEWKVRERPSVDAENWLGQLTLLLEAVRL
                     GGEILANPALPVDRDFARLGLVRSLLGDAAERLGRERAVMSGLIATRMPVPSSRMAEL
                     DEGVVLLAANLLRAERLLRLKPLPPALEDALAALKQDASAYLAEMRAGVMEVGASAGG
                     YPVDERTWFAAVTRVIERTHALSVEVGVLQQDFIARQGEQVSRRAMLGLFSLFALGLT
                     LATGVWLFRRSILAPLGLIEAAAARVSRGELDEPLVVSSGNEVGRVARAFEHMRTSLL
                     ADMRQREAAEIELRKLSLAVEQSPASIVITDIDANITYANAAFVRNTGYRVEEVVGRN
                     PRLLQSGLTPSQTYASMWSVLAAGGMWEGEFQNRRKDGSLLLERVMVAPIRDGDGRVT
                     NYLAVKEDITEKQRMLEELIEYRERLEGLVAERTAELEAARDAAEVANRAKSEFLAVM
                     SHEIRTPMNGVLGLADVLARSSLSPYQIELVDTIRESGSTLLRIIDDILDFSKIEAGG
                     MSFERHRFAVVPFVEGVADALLPVAERYDVELRVHVATDLPARIIGDEGRVRQILTNL
                     MGNAIKFSSRTGRRGLVELRAAGGPDTSLVLSVADNGIGIAEEARDRLFKPFSQAESS
                     TTRRFGGTGLGLAICKRLVDLLGGRIELETEPGHGSLFRVVLPLEALDDPVAPGRPVL
                     AGVCCAVVGVERGRAADMADYLAAEGAVVLHVAAFAELSRRSAWLDADERVVLAHVIP
                     DHEELEPGAERGKGCGVVVLEHGHRRRPRLRRAGLASLDLDLVRHGALIDAVALALGR
                     IQPQRATVACEHVDSAAPVVPDREEAIAEGTLILVAEDDPINRQVIRRQLALLGFAAE
                     IVPDGAQALERWRSGQHALLLTDLHMPVMDGYQLAAAVRREEGARTGARVPIVALTAN
                     ALRGEDARCREAGMDDFLTKPVRVDVLRQVLRRWLHSRDEVGRSSFADSPLQEPALPV
                     LERGVLAGLIGEDPQIHAELLRDYELSLVALAAEIHVAHDANALRKLGDCAHRLKSSS
                     RAVGALAMGALCERLERACREGEDARVDALVVAFRSELDELLAALRRPV"
     gene            complement(12123..13409)
                     /locus_tag="P5537_11820"
     CDS             complement(12123..13409)
                     /locus_tag="P5537_11820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV78773.1"
                     /translation="MNARQPRILVLSDMPVEARQIVSLLADDFPQVSCSTDESHFAAD
                     FDAQHPEVLLLAFRRIEHAERHALVLYRHSRRARSERHHSIVLCDKDNLRQAFELCRK
                     ECFDDYVLYWPLVYDSSRLHMSILLAARMLALGRERAAASEMLAHARVLGSLGEMLDA
                     GLGAGKEHIDALGDSLQAARAAGDALATGLEFASEFASEFELDLDGVPSGLAPAAAAD
                     SLAPSTSAAPPAQVEPAPPPPPQPPSAGAAAVSVPPAALLARLRAHVGEASERAIPLT
                     EWVDGLRREVSPQLDAARKLRGLAAQRPACVLVVDDDRFQCKLLERLLADFDCRLQFA
                     HSGAEAFAALARERPELILMDVQLPDADGVAITRQLKANPALAGIPVIMITGHSERNI
                     LQASLAAGAVDFVVKPFERERMHAKLAKFLHGRGRG"
     gene            complement(13406..>14326)
                     /locus_tag="P5537_11825"
     CDS             complement(13406..>14326)
                     /locus_tag="P5537_11825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004385882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HRV78774.1"
                     /translation="RLAAAYRIDVLGSLVKPVPPSCLQAMLRRWQEGGRHARTASAPA
                     RGYTAAELARAIAQGQLLNHYQPKVDLRSGAFAGVEALVRWQHPEDGLVFPDVFIPGM
                     EASGLIDELTRGVLLRAAADLRALRAQGLRIRLAINVSMDSLDRLAFPELVCAMLDEA
                     GLAPAELILELTESRLGSDPVAALDILARLRLRQIGVSIDDFGTGHSSLRQLRDLPFD
                     ELKIDRGFVTGARKLPTRRAIFCGCLDMARELNIHSVAEGVEDRDDWEFVRASGCDQA
                     QGYFISRPVPAAELPAWHARWRQRRGELIG"
BASE COUNT         2059 a         4641 c         5193 g         2333 t
ORIGIN      
        1 tctgtaggag cgccggcagg cgcgattgcg gcgcgtcgaa ccgcgagatc gcccgccacc
       61 actccattgc cccttcgcgg ctgccgccgc tcctacacgg gtcggagtca cgctggtttc
      121 tgtaggagcg ccggcaggcg cgaatgcggc gcttgcgcgg cgatcagcgc tcttcgatca
      181 ccccgtggcg gtcgagctgc acctcgtcgc agttgtgtcc cgggccgctg cggtcgacga
      241 cgaggaagtc gcacacccct tcgagcgcga gcaacgggtg gtgccagacg ccggtggcgt
      301 agttcacccc ctggtcggcg cgggcgagga agaccttcag gtcctccact ccgggcggtt
      361 cgccggcggg ggcgaccacg accaggtagg gcctgcccga catcgggatg aaggcctgcg
      421 aggcgagcgg gtggcgctcc atcatctgca cggtaaaggg caggctgcgc ggctggccgc
      481 ggaagatgga cacgatcacc cgcccgtcgg ggccgggctc gatgtgggcg aggtcgtggt
      541 agcgctcggt gttgccggcg ttgatggtga agtgctgtgc ggcgtcgctg gcctcgacga
      601 cctcgccgaa gggggcgaag gcctcgcggg tgagcggctt gatctcgagc gtgagggcgg
      661 ggtgcgaggt catggtgtgc tctcgggtga ggaagggggc gacacgccgg tcgggtgccc
      721 gggcgcaggg ctgcgcccgc gaagcgccgg tcttcttatt tggtctcgac cttgccccac
      781 aggcgcagtc gcgagacgcc gccgtcgggg aagatgttga agcgcacgtg ggtgatcggc
      841 ccgagccggg cgacctcgtc cgtgaaggtg tggatcgcgt ccatctcgag cttctgctcg
      901 ggcagcaggg tctgccagaa catcgactgg gtggtgatcg agcggtcggt gccgccggtc
      961 acgtacgccg cctgcaccga gcagcggtcg gggtagttgc ccttgaagaa ggcggtgtcg
     1021 acctcgatgc gctcgaccgt gccgggggtg ccgagctcga gcacgcacca gtcgttgccg
     1081 ggctcgcggc ggcggcgggt ctcccagccg tcgcccatgt tcatgccgcg gccgggcagc
     1141 agcagcgcgg acgccgacga accgaagctg gcgtcgttcc aggagaccgc gcggccgccg
     1201 ttctccatcg ccaccaggtc gaccagcgcg ccggcggccg tggtcgcgag cgtgctcacc
     1261 gggcggccat acacgcgcag gcgggcgatg ccgccgtccg ggtacatgtt cacgcgcagg
     1321 tgggtccagg ccgcggtgct ggtgcactcg aggaggtgat ggcggttggg gcccatcggg
     1381 ctggcgggga ggatctccgt ccaggtcgcc gcctgcagcg cctcgacctc atccgtctcc
     1441 gacacgcagg cctcgatgga gaccgccggc gggtagttgc cggtgaagtg gctggtgtcg
     1501 acgtcgaagc cgcggatcac gcccttgacg ccgagcctga ccagcgccca gtcgtggccg
     1561 gcgacgcgct tcctgcgtga ctcccagccg tccatccact tgccgttggt gtcgaacttg
     1621 ccgggcacga actgggcggg ttcggggttg agcatgcgcg tgacctcggc gaagaagtcg
     1681 tccgaggcgg cgagcgcctt cgcgcccagg cgcgggttgg cgaggtcgac cgagcgcagc
     1741 gcccagtcgg gcagctcggc agcgggggcg aagacggggg cgccgggggt gtggctggcc
     1801 atgggggttc tccttttggg gggttatttc ggggcgtagg ggtggcgctc gatccagtga
     1861 cgggcgacat cgacgcggcg gcacacccac acgcggtcgt gcttctcgat gtggtcgagg
     1921 aagcgctgca gcgcgcggaa gcgccccggg cggccgagca ggcggcagtg catgccgacc
     1981 gacatcatcg ccgggcgctc ctcgccctcg gcgtacatga cgtcgaaggc gtcgcgcagg
     2041 tactcgaaga actcgtcgcc gtgcgagaag ccctgcggca gcgcgaagcg catgtcgttg
     2101 gtgtcgaggg tgtagggcac gacgaggtgc ggcacggtct cgccgtcggt cttctgcacc
     2161 tcggtccaga acggcaggtc gtcgccgtag tagtccgagt cgtacaggaa gccgccgtag
     2221 tcggccacca ggcggcgggt gttgggcgag tcgcggccgg tgtaccagcc cagcgcgcgc
     2281 tcgccggtga ggcgctcgat gagctccatg ccgatcttca tgtgctcgcg ctcgacctcc
     2341 tcgggcgtgt tctggtagtg gatccagcgc cagccgtggc aggcgatctc gtggccgagc
     2401 tccttgaacg cggcggtgag ctcggggtgg cgctcgagcg ccatcgacac gccgaagatg
     2461 gtcatcggca ggccgcggcg ctcgaactcg cgcaggaagc gccacacgcc cacgcgcgcg
     2521 ccgtactcgt agatgccttc catcgacagg tggcgctcgg ggtagctggc ggcgttgaag
     2581 agttcggaga ggaactgttc gctgccggca tcgccgtgca gcacgcagtt ctcgccgcct
     2641 tcctcgtagt tgaggacgaa ctgcaccgcg acgcgggcgc ggccgggcca gtcggcgtgc
     2701 ggcgggttgc ggccgtagcc gacgaggtcg cgggggtagg tcgagtgcga ggtcatggtc
     2761 gggctcctcg cgatcaggcg ccggcgccga acagcgcatc caggcggaag cgggcgatcc
     2821 tgccgatctc gttcagacag gtgcggaact cggtgtcgcg cgcgttggcg agccgtgcct
     2881 cgacgcggtc catgatctgg tgccgtgtca ggcccttgac cgcaaccacg aagggaaagc
     2941 cgaagcgtgc gcggtagtcc tggttgagcc ggcgcaggcg ctcgagctct tccttgctgc
     3001 actggtcgag cccggcaccg cgctgctcgc cggtggaggc ggtggtcagc gtgccggcct
     3061 cggcctcctt gccggcgagc tccgggtggg cgcagatgag gccgagctgc tcggcggggt
     3121 cggcggtgtc gaccaccagg cacatcgcgg cgtgcagcgc gtcgatgctg gtgaaggggc
     3181 cggcgctcca ggcacgctcg gcgatccacg gcgagtgctc gaagatgccg tcgaggcggg
     3241 cgacgaaggc gtcctgcggc aggcgggaca gctcggtcag cgcggccgtc gtgcggtcgg
     3301 gggcggtggc ggtcttggag gtgctcatgg tgtctcttcc ttcctgttct tgtcgttcag
     3361 tccgcggtgc gcgcgccctg ggcgaaccag atggcgatct gctcgcgctc ggcgtcggtg
     3421 atctgcgtca ggttgccgag cggcatgtat ccgctggcca cggtctgcgc gctcatcacc
     3481 gcgttggcgg cgatctgttc ggacgtctcc agcatcaccc ccttgggtgc ctgggcgaag
     3541 ccctcgaagg tcggcttctc ggcgtggcag gcgatgcagc gctgggccat gatcgccttc
     3601 acggtggcga agctgacctt ctcgccaccg gcatcgacct gcttcggcgc catcagcacc
     3661 atcagcagcg cgatcagcgc cacgccggcc gccggcagcc accacttgac ctggccgcgg
     3721 tggcgcagca cgaagaactg gcggatcagc acgccggcca gcatcagcac gcccagcacc
     3781 agccagccgt tggcgttggc ataggtcatc gggtagtggt tgctgatcat gatgaacagc
     3841 accggcaggg tgaagtaggt gttgtgcacc gagcgctgct tgccgatgat gccggggcgc
     3901 ggatcgacct tctcgccggc gtggatctgc gccaccatcc ggcgctgtcc cggcatgatg
     3961 tggaagaaca cgttggccgc catcatcgtg ccgagcatgg cgccgacgtg gatgtaggcg
     4021 ccgcgtgccg agaacacctg gtgcagcacg tagttggcga ccatcaccag cacgaacacg
     4081 atcgccgcga gcaggccgtc cttgccgacc atgttgcggc acaggacgtc gtagaccacc
     4141 cagccggcga ccaggaaggc gatcgagatg cccacggccg ctgccggcga gagcgccatc
     4201 acgctgctgt cgatcaggta gctcgaggcg ccgatccagt agatgatcgc catcatgccc
     4261 atgcccgaca gccaggtggt gtaggcctcc cacttcgacc agtgcaggtc ctgggtgagc
     4321 ggctcgccct tggggccggt gaggtatttc tggctatggt agaagccgcc gccatgcacc
     4381 gcccacagct cgccgaacac gccgcgcgcg ccgtcttcgg gcttcttcgg gggtttgagc
     4441 gagttgtcca gcatcacgaa gtagaaggac gcgccgatcc aggcgatgcc cgcaatcagg
     4501 tgcagccagc ggaccagcag gttggcccag tcgagcagat aggcttccat gatctgttct
     4561 ctttatcgat ttgcgtggaa gcggggctca gctgccgcgg taggtggagt agctccacgg
     4621 cgacaccagc agcggcacgt ggtagtgctg gtccacattg gcgatgccga agcgcagcgc
     4681 gacttcgtcc acgaacagcg gctcgggcag gttcaggccc agggcgcgga agtagtcgcc
     4741 ggcgccgaac acgatctcgt acctgccggc ctccagcgcg gcgccctcga gcagcggccg
     4801 gtcgcagcgg ccatcgtggt tggtgacggt gcgcgcgact tcgcggcgct cgccgtcgag
     4861 ccgatacacg gtgacggcga tgccgacgcc gggcttgccg tgggcggtgt cgaggacgtg
     4921 ggtggtgagg cggcccatgc tgttgtctcc tggttctgtc cgggtatgcg ggaatcgtgt
     4981 gaggcgcagt gtaagccggg gccgtgttaa cggatcgcat atgtccttat atgtgatata
     5041 tgctctcgcg tatcttttcg gtggcgggca gccggcctcg ccccgcatcc ggataacgac
     5101 aaggacgagg agacccgcga tgagcctgcg gcgcagcgac gacccgctcg acacctacct
     5161 gttgcgcgtg ttcgtgctcc tgatcaccga gcgcagcgtg tcgcgcaccg cgctgcgcct
     5221 gaaccagtcg cagccggcgg tgagcgcggc cttgaagcgc ctgcgcgaga tcctcggcga
     5281 tccgctgctg gtgcgggaga agggcggcat ggtgccgacc gagcgtgcgc tcgcgctgat
     5341 gtcgcacgcc aagggcgcgc tcgccgagat cgaccgcatg accgacgcgc ccgagtcctt
     5401 cgagccgaac agcacgcggc acgagttccg cgtcggctcg cccgactatc tggcgccggt
     5461 gttcgtcgcc agcgtggccg agcgcttccg ccgcgaggcg ccacaggcgc gccttagcct
     5521 gcacgcgctg gggccgagct tcgacttcga gcgctcgctc gcggaagggg acctggacgt
     5581 ggtgatcggc aactggcccg aaccgccgca ccgcatgcac ctgtcgatgc tgctcgagga
     5641 cgagatcgtg tgcctggtgg cggccagcca cccgtgcgcg aagaagggga tgagcgtcga
     5701 ggactacatg cgcgccgcgc acgtggtgcc gatgccgtat tcgatcagcc agcgcggggt
     5761 catcgacagc gtgctggcct cgatgcgcat caatcgcgac gagcgcgtgg cggtgcagtc
     5821 cttcaccgcc gcgccctatc tgctgcaggg caccgacctg gtgtttacca ccacccggca
     5881 ctttgcgcag ttctatgccc agctgttgcc gctggcgatc atcccgtcgc cgatcgcgtt
     5941 tccgccgatg cgcttctacc agctctggca cgagcgcaac caccactccn nnnnnnnnnn
     6001 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6061 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnc aggctcagcg gtcgatcggc accagcatca
     6121 ccgggatgtc ggccttcatc gtgaccttgt gcgccaccga gccgagcagc agttcgccga
     6181 tcgtgctgtg gccgcgcgag cccatcacga tcacgtcggc gagcacgtgc ttggcgacat
     6241 ccaggatgcg gcgcgaggcg tcgccctcga gcgcgcgcac gctggcgagc acgctcttga
     6301 cgtcgagctc ggggttggcc tcggcgaaga cgtcgatgcg atggcgcagc agggcctccg
     6361 ccttcttgtg gccggcgagc ttgatctcgt ccatcttctc ttcgctgagg aactcctcgt
     6421 agggcaggct gctcgagggc agggtcacgg tgaccgcgtg cagcttcgcg ttgaacttca
     6481 tcgccaggcc cacggcgtgg cggaacaccg cgggcgagcg cggggtcagg tcggaggcgt
     6541 agaggatcga gcggatttcg tagctcatcg gggaaactcc cggttgcggt ggtgtggtcg
     6601 gcgccggagc gtggcgttcc ggcaggcatc ctgcattctc tcggccggtg gatccggcat
     6661 tgcctgcgca ggcgtcctgg acgaagtgta gagggatgcg ccgcgctgtc gcagccgcgc
     6721 cggccgatag cgcgtatacg cattccctga tgacgcttac gcgccgggtc cgcttgcggc
     6781 cgggccggtg ccggcgggat gatgagagga caacgggccg cgacccgccg ccatggagaa
     6841 tcgcatgatc gatctgtaca ccgccgcaac ccccaacggc cacaaggtct cgatcgcgct
     6901 cgaggagctc ggtctgccgt actcgctgcg cgtgctcgac ctgtccgcca acgagcagaa
     6961 ggagccctgg ttcctcgcca tcaaccccaa tggccgcatc ccggccatcg tcgaccacga
     7021 cgagggcgac ttcgccgtgt tcgaatcggg cgcgatcctg atctacctcg ccgagaagac
     7081 cggccggctg atgccgcagg acgccaaggg gcgctcgcgc gtgctgcagt ggttgatgtt
     7141 ccagatgggc ggcgtcggcc cgatgatggg ccaggccaac gtcttcttcc gctacttccc
     7201 cgagaagctg cagcccgcga tcgatcgtta ccagggcgag gtcaggcggc tcttccgcgt
     7261 gctcgacggc cacctggcca ggaacgaata cctcgccggc gactactcga tcgccgacat
     7321 cgccaactgg gcctgggtgc gcacgcacaa ctggtcgggc gtcgccatcg acgacctgcc
     7381 caacctcgcg cgctggcgcg accgcatccg tgcgcgcccg gcggtgcagc gcggcatcga
     7441 gatgccgccc tccagcctcg acctcgaagg cgaccgcgag gaacgggcca aggcgttttc
     7501 cgacaaggtg cgcaacatgg tcgagaccgg ccagtcgcgc agcggcgggg tctgatcgcc
     7561 cccgcgcccc ggccggacca ggacactcca ggagattgca tgaagctcta tgtttcaccc
     7621 cgtgcgccca acccgcgccg cgtgcagatg ttcatcgccg agaagggcat ccgcggcatc
     7681 gaggaggtcg cggtcgacct cgtcaagggc gagcaccgca gttccgacca ccgcgcgcgc
     7741 agcccgctcg ccaaggtgcc ggtgctggag ctcgacgacg gccgctacct cggcgagacg
     7801 cgcgccatct gcagctatct cgaaggcctc tatcccgagc ccaacctgat gggggagcgc
     7861 ttcgaggagc gcgccttcat cgagatgacc gaccgccgcg tcgagctcta cctcttcggc
     7921 ggcatcatga actgcatccg ccacacccat cccgggctgg cgccgctcga gcagccgcag
     7981 ttcgaggact tcggccgctc gcagggcgag aaggtgcgcg aggtggcgcg ctggctcgac
     8041 gaggaactcg gccgccagcc cttcgtcgcc ggcgagcgct tcaccatcgc cgacatcacc
     8101 gccttctgcg cgatcgagtt cgcgcgcggg ctgatgaagt tcaagcccgg cgccgagggc
     8161 atggccaacc tgcaggactg gcgcgaccgc atcgtggaac gcccgagcgc gcggactgga
     8221 ggctgagatt tcatcccccg cccgcgtcgg cgcgctctgg gctgcgatgt ggccacttgc
     8281 gtcggcaggt accggcgggt cggcgctgcg gtgcaagctc cctacttgcg tttttcctgg
     8341 aattgataaa aacaataaaa ctggctgaaa atccttgtgc tggttatatt tccgcgtcgg
     8401 ggtgtgcctg cgcccccttt atccgctgct cgagggggcg aggtacggga atgtcgattc
     8461 gaaggctgtt tctggtggtg ttcggtctgc tggtgttgct gatcggagtg accttcattc
     8521 cgacgctgtc cgcataccgc actcaggtca cgcacttgcg agcgatcggc gaagccaacg
     8581 tgatcaccgg tgcagtgcag aggctgatgt cggcgctggc cgccgagcgc gggctcggcg
     8641 tactcctgct ctcggcgagt tccggccgtg aggtgctgcg cgcccgtctg ctcgaagcgc
     8701 gcgagctcag cgactacgag tacgtccgct ttcgcagcct tgctgtcccg cgcctcgaga
     8761 atgtcgccga cccgaccggg ctcatggtct acgccgatat cgcacgcgat ttcgccgcat
     8821 tgaaagccct gcgcagtgcg atggacgagt ggaaggtccg cgaacggccc agcgtcgacg
     8881 cagagaactg gctcgggcaa ctcaccttgc ttctggaggc ggttcgtctg ggcggtgaga
     8941 tccttgccaa tcccgctctg ccagtcgatc gcgactttgc ccgtcttggg ttggtccggt
     9001 ccttgcttgg cgatgcggcc gagcgtctcg ggcgtgagcg tgcggtgatg tcgggcctga
     9061 tcgccacgcg catgccggtg ccgtcgagcc ggatggcgga gctggacgag ggcgtggtgc
     9121 tgctcgcggc gaacctgctg cgggcggaac gcctgctgcg gctgaagccc ttgccgccag
     9181 cgctcgagga tgcactggcg gccctgaagc aggatgcctc ggcttacctc gccgaaatgc
     9241 gggcaggcgt gatggaggtc ggcgcctcgg cgggcgggta tccggtcgac gagcggacgt
     9301 ggtttgccgc ggtgacccgg gtcatcgagc gcacccatgc gctgtccgta gaggtgggcg
     9361 tgcttcagca ggacttcatc gcccgccaag gtgagcaggt ttcgcgccgc gcgatgctcg
     9421 gcctgttttc cttgttcgct ctcggtctca ccctcgctac gggcgtgtgg ctgttccgca
     9481 ggtcgatcct cgcgccgctc ggtctgatcg aggccgccgc cgcgcgggtg tcgcgcggcg
     9541 agctcgacga gccgctcgtc gtttcgagcg gaaacgaggt tggtcgggtg gcgcgcgctt
     9601 tcgagcacat gcgcaccagc ctgctcgccg acatgcgcca gcgcgaggct gcggagattg
     9661 agctgcgcaa gctgagcctc gccgtcgagc agagcccggc gagcatcgtg atcacggaca
     9721 tcgacgccaa catcacgtac gccaatgccg cctttgtgcg caataccggc tatcgcgtcg
     9781 aggaggtggt ggggcgcaat ccacgcctcc tgcagtccgg cctgacccca tcccagacct
     9841 acgcgagcat gtggtcggtg cttgcggccg ggggcatgtg ggagggggag ttccagaatc
     9901 ggcgcaagga cggctccttg ctcctggagc gcgtgatggt cgcgccgatc cgcgatggcg
     9961 acgggcgtgt taccaactac ctcgcggtca aggaggacat caccgagaag cagcgcatgc
    10021 tggaggaact gatcgagtac cgcgagcggc tcgagggcct cgtcgctgag cgtaccgccg
    10081 aattggaggc ggcgcgcgat gcggcggagg tggctaaccg ggcgaagagc gaattcctcg
    10141 ccgtcatgag tcatgagatc cgcacgccca tgaacggtgt cctcggcctt gcggacgtgc
    10201 tcgcgcgttc cagtctttcg ccctaccaaa tcgaactcgt ggacaccatc cgcgagtcgg
    10261 ggagcacgtt gctccgcatc atcgacgaca tcctcgattt ttccaagatc gaggctgggg
    10321 gcatgagctt cgagcgccac cgcttcgccg tcgtgccctt tgtcgaaggt gtcgccgatg
    10381 ccctgctgcc ggtggccgag cggtacgacg tcgaactgcg cgtccatgtc gccaccgacc
    10441 tgcccgcgcg catcatcggc gacgaggggc gcgtccgcca gatcctgacc aacctgatgg
    10501 gtaacgccat caagttctcg tcgaggaccg ggcggcgggg ccttgtggag ctccgtgcgg
    10561 caggcgggcc cgacacgtcc ctggtgctga gcgtcgccga caatggaatc ggcatcgccg
    10621 aggaggcgcg agatcgcctg ttcaagccgt tctcgcaggc cgaaagctcg accacgcgac
    10681 gcttcggcgg caccgggctg gggctggcga tctgcaagcg cctggtcgat ctgctgggtg
    10741 ggcgtatcga gcttgagacc gagccgggcc atggcagcct tttccgtgtc gtgctgccgc
    10801 tggaagcgct cgacgatccg gtggcgcccg gccggccggt gctggcaggg gtatgttgcg
    10861 cggtcgtcgg cgtggagcgc gggcgtgcgg ccgacatggc ggactacctc gcggccgaag
    10921 gcgcggtcgt cctccatgtg gcggcgtttg ccgagctctc ccggcgatcg gcatggctgg
    10981 atgccgatga gcgggtcgtg ctcgcacacg tcattcctga ccatgaagag ctcgaacccg
    11041 gcgcggagag gggtaagggc tgtggtgttg tggtgctcga gcacggtcat cgccgccggc
    11101 caaggctgcg ccgtgccgga ctcgcctccc tcgatctcga tctcgtgcgc cacggagcgt
    11161 tgatcgacgc ggtcgcgctg gcgctcggtc gtatccagcc gcagcgtgcc acggtcgcgt
    11221 gcgagcatgt cgacagtgca gccccggtcg tccccgaccg cgaggaggcg atcgccgagg
    11281 gaacgctgat cctggttgcc gaggatgatc cgatcaaccg tcaggtgatc cggcgtcagc
    11341 ttgccctgct cggcttcgcc gcggagatcg tacctgacgg cgcgcaagcg ctcgagcgct
    11401 ggcgtagcgg ccagcatgcg ttattgctga cggatttgca catgcccgta atggatggct
    11461 atcagcttgc cgccgcggtc cgccgggagg agggggcgcg caccggtgcg cgagtgccga
    11521 tcgttgcgct cacggccaac gccctgcgtg gcgaggacgc acgctgccgt gaagccggca
    11581 tggacgactt cctgaccaag ccggtgcgcg tcgatgtgtt gcgtcaggtc ctgcggcgct
    11641 ggctgcattc ccgggatgag gtgggccgct cgtctttcgc ggattcgccg ctccaggagc
    11701 ctgccctgcc ggtgctcgag cggggggtct tggcggggct gatcggcgag gacccgcaga
    11761 tccacgcgga gctgctgcgc gactatgaac tttcgctcgt cgcacttgcg gcggagatcc
    11821 atgtcgcgca cgacgcgaac gcgctgcgca agctgggaga ttgtgcgcac cgcttgaagt
    11881 cttcctcgcg tgcggtgggc gcgctggcga tgggggcgtt gtgcgagcgg ctggaacgcg
    11941 cctgccgcga gggcgaggat gcgcgcgtcg atgccttggt cgtggcgttt cgcagcgagc
    12001 tcgacgaact cctggcggcc ctgcgccggc ctgtctgagg cgcactgcag cggccttgcc
    12061 gcacccgtct ccgacgtgcc tcgggtgtgc ggcaggggcg gcgcgggtcg cgtcgatcgt
    12121 tatcaacctc ggccgcggcc gtggaggaat ttcgccagct tggcgtgcat gcgttcgcgc
    12181 tcgaagggct tgaccacgaa gtcgaccgcg ccggcggcca ggctggcctg gaggatgttg
    12241 cgctcgctgt ggccggtgat catgatcacc gggatgcccg cgagcgccgg gttggccttg
    12301 agctggcggg tgatcgccac gccgtcggcg tcgggcagct gcacgtccat caggatcagc
    12361 tccggacgct cgcgcgcgag cgcggcgaag gcctcggcgc cggagtgggc gaactgcagc
    12421 cggcagtcga aatcggcgag caggcgctcg agcagcttgc actggaagcg gtcgtcgtcg
    12481 accacgagca cgcacgccgg gcgctgcgcg gccaggcccc gcagcttgcg tgcggcgtcg
    12541 agctgcggcg agacctcgcg gcgcaggccg tccacccact cggtgagcgg gatcgcgcgc
    12601 tccgaggctt cgcccacgtg cgcgcgcagc ctggcgagga gggcggcggg cggcacggac
    12661 actgccgccg cgccggcgga ggggggctgg gggggcgggg gcggcgcggg ctcgacctgc
    12721 gcaggcggcg cagcggaggt cgatggcgcg aggctgtccg ccgccgccgc tggcgcgagc
    12781 cccgagggca ccccgtcgag gtcgagctcg aactcggagg cgaactcgga ggcgaactcg
    12841 agcccggtgg cgagcgcgtc gccggccgca cgtgcggcct gcaggctgtc gccgagcgcg
    12901 tcgatgtgct ccttgccggc gccgagcccg gcgtcgagca tctcgcccag gctgccgagc
    12961 acgcgcgcat gcgcgagcat ctcgctcgcc gccgcgcgct cgcggccgag cgcgagcatg
    13021 cgcgcggcga gcaggatgga catgtgcagc cgtgagctgt catacaccag cggccagtac
    13081 agcacgtagt cgtcgaagca ctccttgcgg cacagctcga aggcctggcg caggttgtcc
    13141 ttgtcgcaca gcacgatgct gtggtggcgc tcgctgcgtg cgcgccggct gtggcggtag
    13201 agcacgagcg cgtggcgttc ggcgtgctcg atgcggcgga aggcgagcag cagcacctcg
    13261 gggtgctgcg cgtcgaagtc ggcggcgaaa tggctctcgt cggtcgagca gctcacctgc
    13321 gggaagtcgt cggcgagcag ggagacgatc tgccgggcct cgaccggcat gtcggagagg
    13381 acgaggatgc ggggctggcg tgcgttcatc cgatgagctc cccgcgacgt tgccgccagc
    13441 gcgcgtgcca ggcgggcagt tcggccgccg ggacggggcg cgagatgaag tagccctgcg
    13501 cctggtcgca cccgctcgcg cgcacgaact cccagtcgtc gcggtcttcc acgccctcgg
    13561 cgacggagtg gatgttcagc tcgcgcgcca tgtcgaggca gccgcagaag atcgcccggc
    13621 gcgtgggcag cttgcgcgcg ccggtcacga agccgcgatc gatcttgagc tcgtcgaagg
    13681 gcaggtcgcg cagctggcgc agcgaggagt ggccggtgcc gaagtcgtcg atcgacacgc
    13741 cgatctggcg caggcgcagg cgggcgagga tgtcgagggc cgcgaccggg tcgctgccca
    13801 ggcgcgactc ggtgagctcc aggatcagct cggcgggcgc gagcccggcc tcgtcgagca
    13861 tggcgcagac gagctcgggg aaggcgaggc ggtccaggct gtccatcgac acgttgatgg
    13921 cgagccggat gcgcagcccc tgcgcgcgca gtgcgcgcag gtcggccgcg gcgcgcagca
    13981 gcacgccgcg ggtgagttcg tcgatcagcc ccgacgcctc catgccgggg atgaagacgt
    14041 cggggaagac gaggccgtct tcgggatgtt gccagcgcac cagggcctcg acgcctgcga
    14101 aggcgccgct gcgcaggtcg accttgggct ggtagtggtt gagcagctgg ccttgcgcga
    14161 tcgcgcgcgc gagctcggcg gcggtgtagc cgcgcgcggg ggcgctcgcc gtgcgggcgt
    14221 gccggccgcc ctcctgccag cgccgcagca tggcctgcag gcaggagggg ggaaccggct
    14281 tgacgaggct gccgagcacg tcgatgcggt aggcggcggc caggcg
//
LOCUS       DAOTIN010000081        14002 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_5231_length_14002_cov_9.706604, whole genome shotgun sequence.
ACCESSION   DAOTIN010000081 DAOTIN010000000
VERSION     DAOTIN010000081.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 14002)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 14002)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14002
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5231_length_14002_cov_9.706604"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..887)
                     /gene="ychF"
                     /locus_tag="P5537_11830"
     CDS             complement(<1..887)
                     /gene="ychF"
                     /locus_tag="P5537_11830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002931070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HRV78775.1"
                     /translation="MSLKCGIVGLPNVGKSTLFNALTKAGIQAENYPFCTIEPNVGIV
                     EVPDPRLAALSEIVKPQKIQPAIVEFVDIAGLVAGASKGEGLGNQFLANIRETDAIVH
                     VVRCFADDNVIHVSGSVDPIRDIEVIDTELALADMATVEKALNRYKRPAAAGDKEAKI
                     LVAVLEKCFAQLDQGKAVRALDLSKEEWASLKPFCLITAKPVLYAANVAEDGFEGNPH
                     LDAVRAHAAAEGAEVVALCAAIEAEIADLEDADKKEFLETMGLEEPGLDRLIRAGYKL
                     LGLQTYFTAGVKEVRAWTI"
     assembly_gap    1231..1330
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            1454..2437
                     /locus_tag="P5537_11835"
     CDS             1454..2437
                     /locus_tag="P5537_11835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylase"
                     /protein_id="HRV78776.1"
                     /translation="MRTNWIEAIDARSAAALASGALVPVEAEQVEMDDAGMRFIVRWV
                     SSLAAKDASRSAAAAGGAAEMAGKGGGVQGAAARAEGAGAEAARDAKTVAIPGGPRDP
                     NFNPFLNPDPELTVGPVGDAHVAILNKFPLCARHLVLARRAFEEQLLPLARSDFAALA
                     ALMVEAGGIGLYNGGTAAGASQRHKHVQWMPDDAGNASLRLFVPGLPAGLAEQGVATH
                     AALSMRHCFVRVRCGRGEAVEDAADSLHAGFERARAELGLEAGEDGLLPPFNLLAGEG
                     WLLAIPRRREHFEGISMSAVCFGGTLYTRHREQIEAIRAVGPLRALAAVGY"
     gene            complement(2444..3127)
                     /gene="pth"
                     /locus_tag="P5537_11840"
     CDS             complement(2444..3127)
                     /gene="pth"
                     /locus_tag="P5537_11840"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HRV78777.1"
                     /translation="MSNAAARPPRLIVGLGNPGAEYSETRHNAGFWFCERLADQLGVR
                     FSHESRFHGLVANAREAGMWLLMPQTFMNRSGQAIGALARFYRIEPAEILVVHDELDI
                     PPGQLRLKFGGGLGGHNGLKDTSAHLGTNDYWRLRIGIGHPGDRNEVVNFVLKPARRE
                     EQQQIDEAIDKALALWPQIVRGELNAAATKLNVRPAPPKPPKPPKAPRPVPPDAGAEA
                     PPTTDGSAA"
     gene            complement(3161..3766)
                     /locus_tag="P5537_11845"
     CDS             complement(3161..3766)
                     /locus_tag="P5537_11845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0008097 - 5S rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HRV78778.1"
                     /translation="MQIEFKATKRDAQGTGASRRLRRAGQIPGIIYGGAGEAQPVSMD
                     HNELFHLLRKEAFHASVLSIEVDGAKQNAVLRDVQWHPFKQQVLHLDFQRIAAGEKMH
                     LKVPLHFVGADVAPAVKLGGCMISHTINELDVQCLPKDLPEFIEVDLSTMEAGQSVHI
                     SQIKLPAGVELVQHGEGDPVVATALLVKGAAEAEGEGEQQA"
     gene            complement(3854..4804)
                     /locus_tag="P5537_11850"
     CDS             complement(3854..4804)
                     /locus_tag="P5537_11850"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002931055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0006015 - 5-phosphoribose 1-diphosphate
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009165 - nucleotide biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HRV78779.1"
                     /translation="MPHGSLMVFTGNANPKLGADVTRRLGISLGSATVGRFSDGEVNV
                     ELLENVRGKDVFVLQPTCSPTNDNLMELLVLVDALKRASAGRITAAIPYFGYARQDRR
                     PRSARVPITAKVVANMLQAVGVQRLLTMDLHADQIQGFFDIAVDNVYAAPVLLADLDK
                     QKYDDLLVVSPDVGGVVRARAFAKRMECDLAIIDKRRPKANVSEVMNIIGEVEGRTCV
                     IMDDIVDTAGTLCKAAAALKKHGAKRVLSYCTHAVLSGAAVSRINESELDELVVTDTI
                     PLRDDAKACPRIRQISVASLLADTILRISNEESVSSLFME"
     gene            complement(4896..4972)
                     /locus_tag="P5537_11855"
     tRNA            complement(4896..4972)
                     /locus_tag="P5537_11855"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4936..4938),aa:Gln,seq:ttg)
     gene            complement(5011..5898)
                     /gene="ispE"
                     /locus_tag="P5537_11860"
     CDS             complement(5011..5898)
                     /gene="ispE"
                     /locus_tag="P5537_11860"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HRV78780.1"
                     /translation="MDCPALNILRTPDCSDPTRLFGCPAPAKLNLFLHVVGRRADGYH
                     LLQTAFRLLDWGDTIDFAVRDDGTIRRVNAVPGVPEADDLVVRAARLLQSHTGCTLGA
                     DITVNKVLPMGGGLGGGSSDAATTLIALNRLWGCGLSRERLQALGLQLGADVPVFVFG
                     RDAFAEGVGEALQPLELAPAWYVVISPGVEVPTAEIFSAQDLTRNTPPLIIADFAAST
                     TRNDLQPVACSRYPEVLRVIEWLDVHAPARMTGSGACVFAEVSSEDEAERITKDCPPP
                     WKAWKARSTARHPLYEWLQ"
     gene            complement(5880..6482)
                     /gene="lolB"
                     /locus_tag="P5537_11865"
     CDS             complement(5880..6482)
                     /gene="lolB"
                     /locus_tag="P5537_11865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008320 - protein transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein insertase outer membrane protein
                     LolB"
                     /protein_id="HRV78781.1"
                     /translation="MSRRASHRAPDLSRVLLGAASALLLGACTPTLVREGSQPAARPF
                     LQAFTAEGRLSATDGREAASGRFEWVHAAQHDRLTLFSPLGQVVALLEGGPASASLES
                     ADGNRREAADVNALLPELLGVELPAARLPRWIQAAPAADAEVRDLDTAGRPQQVFDQG
                     WRIDYTGYADDTAAALPRRLEISRGDARVRLIIDSWTALP"
     gene            complement(6479..8194)
                     /locus_tag="P5537_11870"
     CDS             complement(6479..8194)
                     /locus_tag="P5537_11870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HRV78782.1"
                     /translation="MKTQLARIARSLCLAFALGTGGVATAASGDAAEGNLPAQELTPR
                     TLYHFLLAEIAGARGQIGLSAQLYLDLARSTRDPRIARRATEIAMYSRNLVMARGAAE
                     IWMEVAPDSEEARRVLAGLSGAGRAEDINLDAIQFQLARVLAQSNGRLPQNLLSLGHT
                     LARVPDKQAVRSIVMRLTEPYVEVPEAHIARAQAAQAVEDRMGALAAVDRALELRNGW
                     EPAVLLKVQILQQAGAHAEALRVLEAEVARAPASRPLRLAKARALVSAQRFAEARAAF
                     NQLLEASPQDPELLYAVGLLSLQLDDPGAAELHFARALAAGHPQPDLVRLHLGQIAAD
                     RGEGESARKWFGEIESEELRPEADIRSALSLARENRIDEARALLQRDIEDPDLARRYL
                     LAETQILRDAERPAEALALLDAALRESPEDTGLLYEAAMLAERLDRMDLLESRLRRVL
                     ELQPDHAHALNALGYSLADRGLRLEEAEALIARAHELMPQDPFILDSLGWVRFRRGDH
                     DGALAHLQRAYGMRQDAEIAAHLGEVLWTLGRRDEARRIFADALAAHPDNRLLSDTGR
                     RLGIQ"
     gene            8389..9207
                     /gene="mutM"
                     /locus_tag="P5537_11875"
     CDS             8389..9207
                     /gene="mutM"
                     /locus_tag="P5537_11875"
                     /EC_number="3.2.2.23"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004336285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003906 - DNA-(apurinic or apyrimidinic
                     site) endonuclease activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0016799 - hydrolase activity, hydrolyzing
                     N-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA-formamidopyrimidine
                     glycosylase/DNA-(apurinic or apyrimidinic site) lyase"
                     /protein_id="HRV78783.1"
                     /translation="MPELPEVETTCRGIRPHVQGRSLSRLVVRNPRLRVAVAADLPAH
                     IEGARLDTVERRAKYLLLRFSAGTVIVHLGMSGSLRVVAAAEPPGGHDHVDFVFGEEA
                     LRLRDPRRFGMVVWQPGEAAAHPLLAHLGPEPLGDGFDAAYLLRITRGLRAPIKHVLM
                     DGRKLVGVGNIYASESLFRARIHPLEPAGSLGPRRCARLVACVRETLADAIAAGGSTL
                     RDFVGGDGRPGYFQQQYFVYGRDGEPCRVCGTPVRRIVSAQRASFYCPRCQRRG"
     gene            9365..>11294
                     /locus_tag="P5537_11880"
     CDS             9365..>11294
                     /locus_tag="P5537_11880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dynamin family protein"
                     /protein_id="HRV78784.1"
                     /translation="MTDLTEQFSAYGRWRGQASDAVARLRAWLARNDVGNAQADLRLQ
                     YLLDRLRDDKLTVAFVAEFSRGKSELINAIFFADHGDRILPSSAGRTTMCPTELQWHK
                     GAQPELRLLPIRSRARQTPVSELKRYPEEWTVLALDSIDAPGLQAALARVGEIERVEV
                     GEAQALGFRVDPAGDDGIRPDAEGRIEIPRWRHAVIQFPHPLLEQGLVVLDTPGLNAI
                     GAEPELTLSMLPNAHAVLFILAADTGVTQSDLAVWRNYVQAGAERQRGRLVVLNKIDG
                     LWDGLRDEARIEAEIGRQVDSVAATLGVEPAAVFPVSAQKGLVARIQGDEAVLARSRI
                     PLLERALAEDLLPTKQEIVREDTLAETAEVAAATRSLLEARLAGLREQLQELTDLRGK
                     NQSVIEYMMRKIRSEKDEFEQGLQKYYAVRTVFTDLANNLFAHMGLDAVRDETRRTRE
                     AMLESSFTRGLRNAMQGYFRSLRGNLQRSTEEIAEITRMLDAMYKRFSVEHGLKLTAP
                     EGFSTLRYEKELDRLESAFNRQINTALTLVTTEKHALTQKFFETVAVQARQTFELANR
                     DVEQWLRAVMSPLETQVREYQIQLKRRLESVKRIHEATDTLESRVEELVQGEEALRAL
                     LAELDTLEAAIADTLGVPG"
     assembly_gap    11295..11394
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<11395..11594)
                     /locus_tag="P5537_11885"
     CDS             complement(<11395..11594)
                     /locus_tag="P5537_11885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004379880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhL family 4Fe-4S dicluster ferredoxin"
                     /protein_id="HRV78785.1"
                     /translation="MALMITDECINCDVCEPECPNGAIYQGEEIYEIDPNKCTECVGH
                     FDEPQCQQVCPVDCIPLDPKHE"
     gene            complement(11614..12102)
                     /gene="coaD"
                     /locus_tag="P5537_11890"
     CDS             complement(11614..12102)
                     /gene="coaD"
                     /locus_tag="P5537_11890"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004379882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HRV78786.1"
                     /translation="MKEAIAVYPGTFDPFTRGHEDLVRRASILFEKVVVAVARSNSKN
                     PIFGLDDRVDIARDAVSAFPNVEVVGFDCLLMEFLKQQDARVIIRGLRAVSDFEYEFQ
                     MAGMNRKLYPDVETVFLTPGEEFMFISATMVREIARLGGDVSKFVQPRVLARLQERLK
                     SK"
     gene            complement(12099..12638)
                     /gene="rsmD"
                     /locus_tag="P5537_11895"
     CDS             complement(12099..12638)
                     /gene="rsmD"
                     /locus_tag="P5537_11895"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HRV78787.1"
                     /translation="MSRVRIVGGEWRSRLLDVTSVPGLRPTPDRVRETLFNWLGQDLD
                     GQACLDLFAGTGILGFEAASRGAASVLMVERDARALDALHKAAKTLQAAQVEIVRGDA
                     VRFVQTTPQTFDGVFLDPPYKQGWLEQVSPWLDRLVRPDGWLYVESEAAVDSLGAWRT
                     VKQGRAGQVHFHLMRRSEE"
     gene            complement(12635..13993)
                     /locus_tag="P5537_11900"
     CDS             complement(12635..13993)
                     /locus_tag="P5537_11900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004379887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pitrilysin family protein"
                     /protein_id="HRV78788.1"
                     /translation="MSDLLRTAALVLGASAAAGALAAPEIIEWTAPTGARVHFVESRA
                     LPLVDIQVSFAAGGALDPAGKAGLASMTQALLDAGAGGLDEQTIADRKADLGIAVSGG
                     TDNDRASLALRSLSSAAELDAAVELAATLLARPDFPAAVLERERSRAIAGLREALTKP
                     ATLAARQFNAALYAGHPYGHDSTPESLAAIRREDLIDFHRRHYGANRAAVAIVGDVDR
                     AAAERIAIRLTADLPTTEAAAPLPAPAPTTAQVFRIPHPSAQAHILVGQPGMAREDAD
                     YFPLLVGNYVLGGGGFVSRLTAEVREKRGFAYSVYSALSPQQVAGPFQISLQTRGGQA
                     EEALAVVRATLAGFLAEGPSAEELQAAKDNLVNGFGLRLDSNAKLLDYVSMIGFYRLP
                     LDWLERYPQQVAAVDVAAVREAWQRRIRPEQLVTVIAGGDGDRPAAAEAASATPPAEA
                     AQ"
BASE COUNT         1972 a         4590 c         5100 g         2140 t
ORIGIN      
        1 tggatggtcc aggcgcgcac ttccttcacg ccggcggtga agtaggtctg caggccgagc
       61 agcttgtagc cggcacggat caggcggtcg aggccgggct cctcgaggcc catggtctcg
      121 aggaattcct tcttgtcggc gtcctcgagg tcggcgatct cggcctcgat cgccgcgcac
      181 agggcgacca cctcggcacc ctcggccgcg gcgtgggcgc gcacggcgtc caggtgcggg
      241 ttgccctcga agccgtcctc ggcgacgttg gcggcgtaca gcaccggctt ggcggtgatt
      301 aggcagaagg gcttgaggct ggcccattcc tccttcgaaa ggtcgagcgc gcgcacggcc
      361 ttgccctggt cgagctgggc gaagcacttc tcgagcaccg cgacgaggat cttggcttcc
      421 ttgtcgcccg cggctgcggg gcgcttgtag cggttgagcg ccttctcgac cgtggccatg
      481 tcggcgagcg cgagctcggt gtcgatgacc tcgatgtcgc ggatcgggtc gacgctgccg
      541 gagacgtgga tcacgttgtc gtcggcgaag cagcgcacca cgtgcacgat ggcgtcggtc
      601 tcgcggatgt tggcgaggaa ctggttgccc aggccctcgc ccttggaggc accggcgacc
      661 aggccggcga tgtcgacgaa ctcgacgatg gcgggctgga tcttctgcgg cttgacgatc
      721 tcggacagcg cagccaggcg cgggtcgggg acctcgacga tgccgacgtt gggctcgatg
      781 gtgcagaagg ggtagttctc ggcctggatg ccggccttgg tcagcgcgtt gaagagggtc
      841 gacttgccga cgttgggcag gccgacgatt ccgcatttca ggctcatgtg aatccttgat
      901 cgttccggtg gctgcgtcgc cgcgtcgtgg ggctacggcc ttgatccggt gtggaaaacg
      961 cgggattgta ccgtgtcgcg gggtagggct ccaaaagcgg gcgcgggggt ggtcgcgctc
     1021 gggcggtggg gatggctgcg gtgaagcttg cggaaatggc gccggcgccg ccatgcaagc
     1081 gccgccttcg cgcctgccgg cgctcctaca gaaagcacgg cgtttcccgc cggcctgcag
     1141 gaactgcggc agctgcgaac cgggcgatcg ggcaggcgcg cgtgcagggc cccgccgccg
     1201 ctttcgcgcc tgccggcgct cctacagaac nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1321 nnnnnnnnnn cctgccttct gtgccgcgag gctttggcgc ctcccgtcat ggtcgttgcc
     1381 ggcccattcg tgtcgcggtc ggcctacaat tccctgtcct gcatttgccc aaaaatatac
     1441 cggaggagaa ggcatgagga ccaactggat cgaggcgatc gatgcgcgca gcgcggcggc
     1501 gttggcgtcg ggggcgctgg tgccggtgga ggccgaacag gtcgagatgg acgacgcggg
     1561 catgcgcttc atcgtgcgct gggtgtcctc gctcgcggcc aaggatgcga gccggagcgc
     1621 cgcggccgcc ggaggggcgg cagaaatggc gggcaagggc ggaggcgtgc aaggtgccgc
     1681 ggcgcgggcc gagggcgccg gcgcagaggc tgccagggac gccaagacgg tggcgatccc
     1741 cggcgggccg cgcgatccga atttcaaccc tttcctcaat cccgacccgg agctcacggt
     1801 cgggccggtg ggcgatgccc acgttgcgat cctgaacaag ttcccgctgt gcgcgcgcca
     1861 cctggtgctg gcgcggcggg cgttcgagga gcagctgctg ccgctggcgc gcagcgactt
     1921 cgccgcgctc gccgcgctga tggtcgaggc gggcgggatc gggctctaca acggcggcac
     1981 cgccgcgggg gcgagccagc gccacaagca tgtgcagtgg atgccggacg acgccggcaa
     2041 cgccagcctg cggctgttcg tgcccgggct gccggcgggg ctggcggagc agggcgtggc
     2101 gacgcatgcg gcgctgtcga tgcggcattg ctttgtgcgc gtgcgctgcg gtcgcggcga
     2161 ggcggtggag gacgcggccg acagcctgca cgcgggcttc gagcgcgcgc gcgccgagct
     2221 gggcctggag gcgggggagg atgggctgct gccgcccttc aacctgctcg cgggcgaggg
     2281 ctggctgctg gcgattccgc gcaggcggga gcacttcgaa ggcatctcga tgagcgcggt
     2341 gtgctttggc ggcacgctgt acacccgcca ccgcgagcag atcgaggcga tccgcgcggt
     2401 cggcccgctg cgcgcgctgg cggcggtggg ctactgagcg ggctcaggcg gcggagccgt
     2461 ccgtcgtggg cggcgcctcg gcgccggcgt ctggcggcac gggcctgggc gccttgggag
     2521 gcttcggcgg cttgggcggc gcagggcgga cgttgagctt ggtggcggcg gcgttgagct
     2581 cgccgcgcac gatctgcggc cagagcgcga gcgccttgtc gatggcctcg tcgatctgtt
     2641 gctgctcctc gcgccgcgcc ggcttgagga cgaagttcac cacctcgttg cggtcgccgg
     2701 gatggccgat gccgatgcgc aggcgccagt aatcgttggt gccgaggtgg gcggaggtgt
     2761 ccttgaggcc gttgtggcca ccgaggccgc cgccgaactt gaggcgcaat tggccgggag
     2821 ggatgtcgag ctcgtcgtgc acgacgagga tctcggccgg ttcgatgcgg tagaagcgcg
     2881 caagcgcgcc gatcgcctgg ccggagcggt tcatgaaggt ctgcggcatc agcagccaca
     2941 tgccggcttc acgcgcgttg gccaccaggc catgaaagcg ggattcgtgc gagaagcgca
     3001 cgccgagctg gtcggcgagg cgctcgcaaa accaaaaccc ggcgttgtgc cgggtttcgg
     3061 agtattcggc gcccggattg ccgaggccga cgatcagacg gggcggacgc gcggcggcgt
     3121 tgctcatcgg tcgtcggtct cctgcatccg ggtcgggcga tcaggcctgc tgctcgcctt
     3181 cgccttcggc ttccgccgcg cccttcacca gcagcgcggt cgcgaccacc gggtcgcctt
     3241 cgccgtgctg gaccagctcg acgccggccg gcagcttgat ctgcgagatg tgcaccgact
     3301 ggccggcttc catcgtcgac aggtcgacct cgatgaactc gggcaggtcc ttgggcaggc
     3361 actgcacgtc gagttcgttg atggtgtgcg agatcatgca gccgccgagc ttgacggccg
     3421 gagccacgtc ggcgccgacg aagtgcagcg gcaccttcag gtgcatcttc tcgcccgcgg
     3481 cgatgcgctg gaagtcgagg tgcagcacct gctgcttgaa cgggtgccat tgcacgtcgc
     3541 gcagcacggc gttctgcttc gcgccatcga cctcgatcga cagcacggag gcgtggaagg
     3601 cctccttgcg cagcaggtgg aagagctcgt tgtggtccat cgacaccggc tgggcttcgc
     3661 ccgcgccgcc gtagatgatg cccgggatct ggccggcgcg acgcaggcgg cggctcgcac
     3721 ccgtaccctg cgcgtcacgc ttggtggcct tgaattcgat ttgcatgtga tgctcctgag
     3781 tgggttgtcc ccgcccgcga ccaggcggag acggtggatg cccgcccggc gcgaggccgg
     3841 acgggcgaaa gccttattcc atgaacagcg aggagaccga ctcctcgttg ctgatgcgca
     3901 ggatggtgtc ggcgagcagc gaggccaccg agatctggcg gatgcgcggg caggccttgg
     3961 cgtcgtcgcg cagcgggatg gtgtcggtga ccaccagctc gtcgagctcg gactcgttga
     4021 tgcgcgacac ggccgcgccc gacagcaccg cgtgggtgca gtaggacagc acgcgcttgg
     4081 cgccgtgctt cttgagcgca gcggcggcct tgcacagggt gccggcggtg tcgacgatgt
     4141 cgtccatgat cacgcaggtg cgaccctcga cctcgccgat gatgttcatg acttccgaca
     4201 cgttggcctt ggggcggcgc ttgtcgatga tcgccaggtc gcactccatg cgcttggcga
     4261 aggcgcgcgc gcgcaccacg ccaccgacgt cgggcgacac gacgagcagg tcgtcgtact
     4321 tctgcttgtc gaggtcggcg agcagcaccg gggcggcata gacgttatcg accgcgatgt
     4381 cgaagaagcc ctggatctgg tcggcgtgca ggtccatggt cagcaggcgc tgcacaccca
     4441 ccgcctgcag catgttggcg accaccttgg ccgtgatcgg cacgcgcgcc gagcgcgggc
     4501 ggcggtcctg gcgggcgtag ccgaagtagg ggatggcggc ggtgatgcgg ccggcggagg
     4561 cgcgcttcag ggcgtcgacc agcaccagca gttccatcag gttgtcgttg gtcggagagc
     4621 aggtgggctg caggacgaag acatccttgc cgcgcacgtt ctcgagcagt tcgacgttga
     4681 cctcgccgtc cgagaagcgg ccgacggtgg ccgagccgag ggagatcccc aggcgtcgcg
     4741 tcacgtcggc gccaagtttg gggttggcgt tgccggtgaa gaccatcagg ctgccgtggg
     4801 gcatttctgc tactccgatt gccgtaagga acgacgcgcg aatattcggt gcgtaaaaac
     4861 gactcgggca gacccatggt ctgcccgtcg ttgtatggct ggggaggaag gattcgaacc
     4921 ctcgaatgcc ggaatcaaaa tccggtgcct taaccgactt ggcgactccc caagaaacct
     4981 tttcgctgcg cgtcgagtgc tgcgcgggcg ctattgtaac cactcgtaaa gcggatggcg
     5041 agcggtgctg cgtgccttcc atgccttcca gggtggcgga caatctttcg taatgcgctc
     5101 agcctcatct tccgacgaga cttccgcgaa cacgcaggcg cccgagcctg tcatgcgggc
     5161 cggtgcatgc acatccagcc actcgatcac gcgcaagact tccgggtaac ggctgcacgc
     5221 caccggctgc agatcgtttc gggtagtgct tgctgcgaag tccgctatta ttaagggcgg
     5281 tgtattcctc gtcaagtcct gcgccgaaaa aatttcggcg gtcgggactt cgactccggg
     5341 cgagatcacc acgtaccacg ctggcgcaag ctcgagcggc tgcagcgcct cgcccacgcc
     5401 ctcggcgaag gcgtcgcggc cgaacacgaa caccggtacg tcggcgccaa gctgcagccc
     5461 gagcgcctgc agccgctcgc gcgacaatcc gcagccccac aggcggttca gtgcgatcag
     5521 cgtggtcgcc gcgtccgagc tgccgccgcc gagcccgccg cccatcggca gcaccttgtt
     5581 caccgtgatg tcggcgccga gcgtacagcc ggtgtgcgac tgcaacaggc gggcggcgcg
     5641 cacgacgagg tcgtcggcct cggggacgcc gggcaccgcg ttgacgcggc ggatcgtgcc
     5701 gtcgtcgcgc acggcgaagt cgatcgtgtc accccagtcg agcaggcgga aagcggtctg
     5761 cagcaggtga tagccgtcgg cgcgacggcc gacgacgtgg aggaagaggt tgagcttggc
     5821 cggggcgggg cagccgaaga gccgcgtcgg gtcgctgcag tccggcgtgc gcaggatgtt
     5881 cagggcaggg cagtccatga gtcgatgatc agccgcacgc gggcgtcgcc gcgcgagatt
     5941 tccaggcgac gcggcaaggc cgcggcggtg tcgtcggcat agccggtgta gtcgatgcgc
     6001 cagccttggt cgaagacctg ctgcggccgg ccggcggtat cgaggtcgcg gacctctgcg
     6061 tctgcggcgg gcgcggcctg gatccagcgc ggaagccgtg cggcgggcag ctcgacgccg
     6121 agcaactcgg gcagcaacgc gttcacgtcg gcagcctcgc gccggttgcc gtcggcggac
     6181 tccaggctcg cgctcgccgg gccgccttcg agcagggcga cgacctggcc gagcgggctg
     6241 aagagcgtaa ggcggtcatg ttgggcggcg tgcacccatt cgaagcgtcc gctcgccgcc
     6301 tcgcggccgt cggtcgccga tagccgtcct tcggccgtga aggcctgcag gaaggggcgt
     6361 gcggcaggct gcgagccttc gcgcaccagc gtcggcgtgc aggccccgag cagcagtgca
     6421 ctggcggcgc ccagcagaac ccggctcagg tccggtgcgc gatgcgaagc ccgcctgctc
     6481 actggatgcc cagccggcgg ccggtgtcgc tcagcaggcg attgtcgggg tgtgcggcga
     6541 gggcgtcggc gaagatgcgc cgcgcctcgt cccggcgccc gagcgtccac agcacctcgc
     6601 cgaggtgcgc ggcgatctcg gcgtcctggc gcatgccgta ggcgcgctgc aggtgggcga
     6661 gtgcgccgtc gtggtcgccg cggcggaagc gcacccagcc gaggctgtcg aggatgaagg
     6721 ggtcttgcgg catgagctcg tgcgcgcgtg cgatcagcgc ctcggcttcc tccaggcgca
     6781 ggccgcggtc ggcgagcgag tagccgagcg cgttgagcgc atgcgcatgg tcgggctgca
     6841 gctccagcac ccggcgcagg cgggattcga gcaggtccat gcggtcgagg cgttcggcca
     6901 gcatggcggc ctcgtagagc aggccggtgt cttcggggct ctcgcgcagg gcggcatcca
     6961 gcagcgcgag cgcttcggca gggcgctcgg cgtcgcgcag gatctgggtc tcggcgagca
     7021 ggtagcggcg ggccaggtcg gggtcctcga tgtccctctg cagcagggcg cgcgcctcgt
     7081 cgatacggtt ttcgcgcgcc aggctcaagg cgctgcggat atcggcctcg ggacgcagtt
     7141 cctcgctctc gatctcgccg aaccatttgc gcgcactctc gccctcgcca cggtcggcgg
     7201 cgatctggcc gaggtgcagg cggaccaggt cgggttgtgg atggccggcg gcgagcgcgc
     7261 gcgcgaagtg cagctcggcc gcgccggggt cgtcgagctg tagggacagc agccccaccg
     7321 cgtagagcag ctccgggtcc tgcggcgagg cctcgagcaa ctggttgaag gccgcgcgcg
     7381 cctcggcgaa gcgctgtgcg ctcaccagtg cgcgcgcctt cgccaggcgc agcggccggc
     7441 tcgccggtgc gcgcgccacc tcggcctcga gcacgcgcaa ggcctccgca tgcgcgccgg
     7501 cctgctggag gatctgcacc ttcagcagca ccgctggttc ccagccgttg cgcagctcga
     7561 gcgcacgatc caccgcggcg agcgcgccca tcctgtcctc caccgcctgc gccgcctgtg
     7621 cgcgggcgat gtgcgcctcg gggacctcga cgtagggctc ggtcaggcgc atcacgatgc
     7681 tgcgcacggc ctgcttgtcc ggcacgcggg cgagcgtgtg gccgaggctc agcaggttct
     7741 gcggcaggcg gccgttcgac tgcgccagca cgcgcgcgag ctggaactgg atggcgtcga
     7801 ggttgatgtc ctcggcgcgg ccggcgccgc tcaggccggc gagcacgcgg cgcgcctcct
     7861 ccgagtcggg tgcgacctcc atccagatct ccgccgcgcc gcgcgccatg accaggttgc
     7921 gcgagtacat cgcgatctcg gtggcgcggc gggcgatgcg cgggtcgcgc gtgctgcggg
     7981 cgaggtccag gtagagctgg gccgacaggc cgatctgccc gcgcgcgcct gcgatttcgg
     8041 cgagcaggaa gtgatagagc gtgcgcgggg tgagctcctg cgcaggcagg ttgccctcgg
     8101 cggcgtcgcc gctggccgcc gtcgcgacgc cgccggtgcc gagcgcgaag gccaggcaga
     8161 gggagcgggc gatgcgggcg agctgggttt tcatgggagg cattccggag cttcggtggg
     8221 ttgcggcaga gccggagcgc agcgaccgcc aggcgcccgc tgggcgccgc gaacgcttcg
     8281 agtgctcggc tacaattcgg ttcatgccat ggtaggcaga tcgctgcccc tgccgcaacc
     8341 cgtcctccgc gtgcgcctgc gtgcagagcg tttccaggtt ccgctccaat gcccgaactg
     8401 cccgaagtcg agaccacctg ccgcggcatc cgtccgcatg ttcaaggccg cagcctgagc
     8461 cggctggtgg tgcgcaatcc gcgcctgcgc gtggcagtgg ccgccgacct gcctgcgcac
     8521 atcgaggggg ccaggctcga caccgtggag cggcgggcca aatacctgtt gctgcgcttt
     8581 tccgcgggca cggtgatcgt gcacctgggg atgtcgggca gcctgcgggt ggtcgcggcg
     8641 gccgagccgc cagggggaca cgatcacgtc gacttcgtct tcggtgagga ggcgctgcgc
     8701 ctgcgcgatc cgcgccgttt cggcatggtg gtgtggcagc ccggcgaggc ggcggcgcat
     8761 ccgctgctcg cccacctggg gcccgagccc ctcggcgacg gcttcgacgc cgcctacctg
     8821 ctgcgcatca cgcgcgggct gcgtgcgccg atcaaacacg tgctgatgga cggccgcaag
     8881 ctcgtcggcg tgggcaacat ctatgcgtcc gagagcctct tccgcgcccg catccatccg
     8941 ctcgagcctg ccggcagtct cgggccgcgc cgctgcgcgc gcctggtggc gtgcgtgcgc
     9001 gagaccctcg ccgacgcgat cgcagccggc ggaagcacgc tgcgcgactt cgtcggcggc
     9061 gacggtcggc cgggctattt ccagcagcag tatttcgtct atggccgcga tggcgagccc
     9121 tgcagggtgt gcggcacgcc ggtgcggcgc atcgtcagcg cgcagcgcgc cagcttctac
     9181 tgcccgcgct gccagcggcg cggctgaaac cagcgccatc cccggcgcgc atgcagtcgg
     9241 cgtgcaatat ggcacgcgcg cgcgccgcga agcgggttat ggtgaataat ggattgtgat
     9301 gcgggacgca gcggccctgc ccgcgcgcgc cccgagccca ccagcctgcc ggacgagcac
     9361 gccgatgacc gatctcaccg aacagttttc cgcctatggc cgctggcgcg gccaggccag
     9421 cgacgcggtg gcccgcctgc gtgcgtggct ggcgcgcaac gacgtcggca acgcacaggc
     9481 cgatctgcgt cttcagtacc tgctcgaccg cctgcgcgac gacaagctca ccgtggcctt
     9541 cgtcgccgag ttctcgcgcg gcaagtccga gctcatcaac gcgatcttct ttgccgacca
     9601 tggcgaccgc atcctgccct cgagcgcagg tcgcaccacg atgtgcccga ctgagctgca
     9661 gtggcacaag ggggcgcagc ccgagctgcg cctgctgccg atccgcagcc gcgcgcgcca
     9721 gacgccggtg agcgagctca agcgctatcc cgaagaatgg accgtgctcg cgctcgactc
     9781 gatcgacgcg cccggcctgc aggccgcgct cgcgcgcgtg ggcgagatcg agcgcgtcga
     9841 ggtcggcgag gcgcaggcgc tcggcttccg cgtcgatccc gccggggacg acggcatccg
     9901 ccccgacgcc gagggccgca tcgagatccc gcgctggcgc catgcggtga tccagttccc
     9961 gcaccccctg ctcgagcagg gcctggtggt gctcgacacg ccgggcctca acgcgatcgg
    10021 cgccgagccc gagctcaccc tgtcgatgct gcccaacgcg cacgcggtgc tgttcatcct
    10081 cgccgccgac accggcgtca cccagagcga tctcgcggtg tggcgcaact acgtgcaggc
    10141 tggtgcagag cgtcagcgcg gtcgcctggt cgtgctcaac aagatcgacg gcttgtggga
    10201 cgggctgcgc gacgaggcgc gcatcgaggc cgagatcggc cgccaggtcg actcggtcgc
    10261 cgccacgctg ggcgtggagc ccgccgcggt gttcccggta tcggcgcaga agggcttggt
    10321 ggcgcgcatc cagggcgacg aggccgtgct cgcgcgcagc cgcatcccgc tgctggagcg
    10381 cgcgcttgcc gaggatctgc tgcccaccaa gcaggagatc gtgcgcgagg acaccctggc
    10441 cgagaccgcc gaggtcgccg ccgccacgcg cagcctgctc gaggcgcgcc tggccggctt
    10501 gcgcgagcag ctccaggaac tcaccgacct gcgcggcaag aaccagagcg tcatcgaata
    10561 catgatgcgc aagatccgca gcgagaagga cgagttcgag caggggctgc agaagtacta
    10621 cgcggtgcgg acggtgttca ccgacctcgc caacaacctg ttcgcgcaca tgggcctcga
    10681 cgccgtgcgc gacgagaccc ggcgcacgcg cgaggcgatg ctcgaatcga gcttcacgcg
    10741 cgggctgcgc aacgccatgc agggctactt ccgcagcctg cgcggcaacc tgcagcgctc
    10801 gaccgaggag atcgccgaga tcacccgcat gctcgacgcg atgtacaagc gcttcagcgt
    10861 agagcacggg ctcaagctca ccgcacccga aggcttctcg acgctgcgct acgagaagga
    10921 gctcgatcgc ctcgagtcgg ccttcaaccg ccagatcaac accgcgctga ccctggtcac
    10981 caccgagaag cacgcgctca cgcagaagtt cttcgagacc gttgcggtac aggcgcgcca
    11041 gaccttcgaa ctcgccaacc gcgacgtcga gcagtggctg cgcgcggtga tgtcgccgct
    11101 cgagacccag gtgcgcgagt accagatcca gctcaagcgc cggctcgaga gcgtcaagcg
    11161 catccacgag gccaccgaca cgctggagag ccgcgtggag gaactggtgc agggcgagga
    11221 ggcgctgcgc gcgctgctgg ccgagctcga caccctcgag gcggcgatcg ccgacacgct
    11281 cggcgtgccc ggcannnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnntcctcg
    11401 tgcttggggt cgagcgggat acagtcgacc gggcacacct gctggcactg cggctcgtcg
    11461 aagtggccga cgcactcggt gcacttgttg gggtcgatct catagatctc ttcgccctgg
    11521 tagatggcgc cgttggggca ctccggttcg cagacgtcgc agttgatgca ttcgtcggta
    11581 atcatcagag ccatggtctt cgcttccttg cgtttacttt gatttgagtc tttcctgcag
    11641 ccgtgcgagc accctgggct gcacgaactt gctcacgtcg ccgccgaggc gggcgatctc
    11701 ccgcaccatc gtggcggaga tgaacatgaa ctcctcgccg ggcgtcagga acaccgtctc
    11761 gacgtccgga tagagcttgc ggttcatccc cgccatctgg aattcatatt cgaagtcgga
    11821 taccgcgcgc agtccgcgga tgatcacgcg cgcgtcctgc tgcttgagga actccatcag
    11881 caggcagtcg aagccgacca cttcgacgtt gggaaaggcg gatacggcgt cgcgggcgat
    11941 gtcgacccgg tcgtccagtc cgaagatcgg gttcttgctg ttgctgcgcg cgaccgcgac
    12001 gaccaccttc tcgaacagga tcgaggcgcg ccgcacgagg tcctcgtggc cgcgggtgaa
    12061 cgggtcgaag gtgcccggat agaccgcgat cgcttccttc attcctcgct cctgcgcatg
    12121 agatggaaat gaacctgtcc ggcgcggccc tgcttgaccg tgcgccatgc gccgaggctg
    12181 tccacggcgg cttcggattc gacatagagc cacccgtcgg gacgaaccag ccggtccagc
    12241 cagggcgaca cctgctcgag ccagccctgc ttgtagggcg ggtcgaggaa cacgccgtcg
    12301 aacgtctgcg gcgtcgtttg cacgaatctt accgcatcgc cgcgcacgat ctctacttgc
    12361 gccgcctgta gggtctttgc ggccttgtgc agcgcgtcga gcgcacgtgc gtcgcgctcg
    12421 accatcagca cgctggcggc gccgcgcgag gcggcctcga agccgaggat gccggtgccg
    12481 gcgaagaggt cgaggcaggc ctgaccgtcg agatcctggc ccagccagtt gaacagcgtc
    12541 tcgcgcacgc ggtcgggcgt cgggcgcagg cccggcacgg acgtcacgtc gagcaggcgc
    12601 gagcgccact ctccgccgac gatgcggacc cggctcactg cgcggcttcc gcggggggcg
    12661 tggcggaggc tgcctcagcg gcggcggggc ggtcgccgtc gccgccggcg atcacggtga
    12721 cgagctgttc cgggcggatg cggcgctgcc aggcctcgcg cacggcggcc acatcgaccg
    12781 ccgcgacctg ctgcgggtag cgctccagcc agtcgagcgg caggcggtag aaaccgatca
    12841 tcgacacgta gtcgagcagc ttggcgttgg agtccaggcg caggccgaag ccattgacca
    12901 ggttgtcctt ggcggcctgc agctcctcgg cgctggggcc ttcggcgagg aagcccgcga
    12961 gcgtcgcgcg caccaccgcg agcgcctcct cggcctggcc gccgcgcgtc tgcaggctga
    13021 tctggaaggg gccggcgacc tgctgcggcg acagcgcgct atacacgctg taggcgaagc
    13081 cgcgcttctc gcgcacctcg gcggtcagcc gtgacacgaa gccgccgccg ccgagcacgt
    13141 agttgccgac cagcagcggg aagtagtccg cgtcctcgcg cgccatgccg ggctggccga
    13201 cgaggatgtg ggcctgcgcc gaggggtgcg ggatgcggaa gacctgcgcc gtggtcggcg
    13261 ccggcgcggg cagcggggct gcggcctccg tcgtgggcag gtccgcggtg agacggatcg
    13321 cgatgcgctc ggcggcggcg cggtccacgt cgccgacgat cgccaccgcg gcgcggttgg
    13381 cgccgtagtg gcggcggtgg aagtcgatca ggtcctcgcg tctgatcgcg gcgagcgatt
    13441 cgggtgtgct gtcgtggccg taagggtggc cggcgtagag cgcggcgttg aactggcgcg
    13501 cggcgagcgt ggcgggcttg gtcagcgcct cgcgcaggcc ggcgatcgcg cggctgcgct
    13561 cgcgctcgag cacggcggcg ggaaagtcgg ggcgggcgag cagggtggcg gccagctcga
    13621 ccgcggcgtc gagctcggcg gcggaggaca ggctgcgcag cgcgaggctg gcgcggtcgt
    13681 tgtcggtgcc gccggagacg gcgatgccga ggtcggcctt gcggtcggcg atggtctgct
    13741 cgtcgaggcc gccggcgcca gcgtccagca gggcctgggt catgctcgcc aggccggcct
    13801 tgcctgcggg gtcgagcgcg ccgccggcgg cgaaggagac ctggatgtcg accagcggca
    13861 gcgcgcggct ctcgacgaag tgcacccgcg cgccggtggg cgcggtccat tcgatgatct
    13921 cgggggcggc gagcgcgccg gccgcggcgc tggcgccgag gacgagcgcg gcggtacgca
    13981 gcaggtcgga cagcgaccgg ga
//
LOCUS       DAOTIN010000082        14001 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_5233_length_14001_cov_9.519647, whole genome shotgun sequence.
ACCESSION   DAOTIN010000082 DAOTIN010000000
VERSION     DAOTIN010000082.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 14001)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 14001)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14001
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5233_length_14001_cov_9.519647"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(1..844)
                     /locus_tag="P5537_11905"
                     /pseudo
     CDS             complement(1..844)
                     /locus_tag="P5537_11905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939960.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNB domain-containing ribonuclease"
     gene            complement(1613..2491)
                     /gene="rarD"
                     /locus_tag="P5537_11910"
     CDS             complement(1613..2491)
                     /gene="rarD"
                     /locus_tag="P5537_11910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter RarD"
                     /protein_id="HRV78789.1"
                     /translation="MFAALAAFVTWGLAPLYFRALGSVPPFEIVAHRVLWSALLLALM
                     LATLHFTGGFERVGAVLRQPRLLALLALTSLLTSSNWLVFIWAIDAGRLLEASLGYFI
                     NPLVSVALGAIFLGERLRPLQATAVAIACAGVAWRVWQLGSLPWIPLFLAGTFGLYGL
                     LRKRAPVDAVGGLFIETLVVAPLALAWLLWLHAQGSLAFGSGNPAEWLLPLTGVITAI
                     PLMLFAVGARRLPLATVGFLQYIAPSLNFLVAVLLFREPFDTTQLVGFALIWLALAVY
                     SADMVRAGRQAARRAR"
     gene            complement(2755..3624)
                     /locus_tag="P5537_11915"
     CDS             complement(2755..3624)
                     /locus_tag="P5537_11915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HRV78790.1"
                     /translation="MSHPNDPAQPGFDARRFKAMERAGFNRIAARYAEGAHLRADLAE
                     ALLDAAALAPGQRVLDLASGPGLLAGQAALRVVPGGSVLATDIAEGMLAEGARRCGEH
                     ADTPCFAAADAEHLCLADACMDRVLAGLALFIFPHPERALAEMHRVLVPGGRVALSVW
                     GARETVPLIHRAQDTIARLLPPPKVARPSVFRYGEPEVLSATLAAAGFDDIDIRPCAF
                     SCHFADADAYWQAFLDLAGGAAEALGRLPEPVQAQLRAAVADDLAHHCCDDGRGGFLM
                     PARTLVASARRPD"
     gene            complement(3650..4276)
                     /locus_tag="P5537_11920"
     CDS             complement(3650..4276)
                     /locus_tag="P5537_11920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004377931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqiA/YcfP family alpha/beta fold hydrolase"
                     /protein_id="HRV78791.1"
                     /translation="MIIYLHGFRSAPASIKARALKARMTERGLAERFWCEQLPVSPRA
                     AIALAEGEIARARAAGLDPTVVGSSLGGYYATWLAERHDLRAVLVNPAVVAPLSLEAY
                     VGMQDNLYTGERFEFTRGHIDELRALEVPTITRPQRFWLMVETGDEVLDYRHAVERYA
                     GARQTVLEGGEHGFSRWNDYLDEVIAYAGLGDAPLARLGGAKPAAPRP"
     gene            complement(4291..5115)
                     /locus_tag="P5537_11925"
     CDS             complement(4291..5115)
                     /locus_tag="P5537_11925"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004377930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HRV78792.1"
                     /translation="MDLSLLLVALVLGIVEGLTEFLPVSSTGHLIIIGDLLGYNDDTS
                     KVFKIVIQLAAILAVCWDYRERLIKVAGGVTTEPSAQRFVWLLFIGFLPAAILGLMFH
                     STIKGLLFNPITVATALVVGGLIILYVEKRAYHPRINDVDDMRWTDALKVGFAQALAM
                     IPGTSRSGATIMGGVIFGLSRKTAAEFSFFLAIPTMFAATAYDLYKNWTLLRLEDLPV
                     FAVGFVASFVAAMWAVKSFIKFISNHTFIVFAWYRIAFGIFVLATWYFGWVEWSEP"
     gene            complement(5192..5446)
                     /locus_tag="P5537_11930"
     CDS             complement(5192..5446)
                     /locus_tag="P5537_11930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004377929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HRV78793.1"
                     /translation="MDCRPGCAACCIAPSISSPIPGMPDGKPAGVRCVQLDESGHCRL
                     FGDPRRPAVCSSLKPGAEMCGADREHALHFLATLETMTAA"
     gene            complement(5450..5965)
                     /locus_tag="P5537_11935"
     CDS             complement(5450..5965)
                     /locus_tag="P5537_11935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2478 domain-containing protein"
                     /protein_id="HRV78794.1"
                     /translation="MPAHAIAAVVYKPTDNIEALLARAARALGERGVRLGGVLQHDIA
                     TVIEDPCAMQLENLETGESIPLSQELGRGSISCRVDPDALARGSMAVRGAIARGVDLI
                     IINKFGAQEVAGSGLRDEMAETVVAGVPLLTAVGERFLAEWKEFTGGEGVLLEPTLDA
                     ILAWWSAPRAG"
     gene            6079..>6617
                     /locus_tag="P5537_11940"
     CDS             6079..>6617
                     /locus_tag="P5537_11940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HRV78795.1"
                     /translation="MRAEHKGERRPSALPNFDDCLSVDRPRLRRMARDLSRPPRADER
                     AAAQRLRLQADFDALLERSRAALLARRAALPVPDFPAELPVSARRDEIAGALAAHQVI
                     IVCGETGSGKTTQLPKIAMTLGRGVAGLIGHTQPRRLAARATASRIAQELKSALGEVV
                     GYKIRFTDKTSERSHVKLMT"
     assembly_gap    6618..6717
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <6718..10170
                     /gene="hrpA"
                     /locus_tag="P5537_11945"
     CDS             <6718..10170
                     /gene="hrpA"
                     /locus_tag="P5537_11945"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase HrpA"
                     /protein_id="HRV78796.1"
                     /translation="PVESEDVDPAAAARASARGGKEGDKSRAGGRDKSRDLMDALVDA
                     VDEAQRCGPGDVLVFLPGEREIREAAEALRKAHHLPGTEILPLFARQSAQEQARVFSA
                     SNGRRVVLSTNVAETSLTVPGIRYVVDTGLARIKRYSPRNKVEQLQVEKIAQSAAQQR
                     AGRCGRVMDGICIRLYDEDDFNRRPEHTDPEILRSSLAGVILRMKALKLGAVEDFPFI
                     DAPGSRLIGDGYALLAELGAVTDDDERKLTPTGIELAKLPLDPRIGRMILAARDRGAL
                     AELLVIAAALSVQDPRERPQDSPGAADQAHARFRGGEQDQKSEFLWYWHLWKAWDEVQ
                     RHETSSKQKAWCKKHFLNYMRMREWRDVFAQLHTLCAEHGWKENAQPANYEAIHKALL
                     AGLLGNIGCKADEGESAGKGPQAGSYLGARGIRFWPHPGSALAKKAGKWIMAAEQVET
                     SRLFGRCIARIEPEWVEEVGGHLVKRQVFEPHWSKSSGAVRAWERGTLYGLVIYPRRG
                     VAYRDIDPALCRELFIREGLVQGEIAEGPARAMAFLAHNQRLVAEIERLEHKSRRPDV
                     LVDETLIEAFYDSKLPADVCDVAGLEAWRKAAEKAEPKLLHLSREQLMRHEAEGVTTD
                     RFPPALEVLGQKLKLTYLHQPGEADDGVTLAVPLAMLNQVPANRCEWLVPGLLEEKVA
                     ALMKTVPQKHRHRLQPVAESAAAFMAAFEAGEFDADEPLLKMLQRFVEERVQLKLPLE
                     SFRAENLKPHCFMNFRVIDEHGRVMGQSRNLMELRARFREQVAARFSAAKIGGALAGA
                     LSAAGVAGAEAGQGRGEGADGMARRAGAAEAAGAAAAAGTAQPGRKGSGKAAGDAPGR
                     GAAAAELPAQALSGFSAWTFGALPELLEVRVAGREVIGFPALHDDGDSVSLRPHDTPE
                     EAARVHRRGLARLFALNLKDQVRAVERLPGLRELALQYMSFGTEAELKARLVEATLSR
                     CCLLEPLPTDADAFARRCAEAKSRVSLVAQEFMRLTGQLLVEHAALQKRLSGLKTFPE
                     VVADLQAQLGALLPKDFLVAFEWDKLAHFPRYLKGASVRLDKLRNNPARDAQSMSEWK
                     QLAQAWERERLARRRAGVEDPALEEFRWLLEELRVGLYAQELRTPMPVSVKRLQKIWE
                     SRPR"
     gene            complement(10249..10587)
                     /locus_tag="P5537_11950"
     CDS             complement(10249..10587)
                     /locus_tag="P5537_11950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78797.1"
                     /translation="MNTTLTRKIVTALLCGGILAAAAPAAHADRDDRGPRWGHHKHHY
                     KHDHKHRRHWDERTVYREKVIIRERPRYYREPEIHNHYYERPHRSYSYSRSPAVVIGV
                     DIPPLVIPLR"
     gene            10824..11207
                     /gene="rpsF"
                     /locus_tag="P5537_11955"
     CDS             10824..11207
                     /gene="rpsF"
                     /locus_tag="P5537_11955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004344926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HRV78798.1"
                     /translation="MRHYEIVFIVHPDQSEQVPAMVERYKSIVTTRNGQIHRLEDWGR
                     RQMAYPIQKVHKAHYVLMNIECDGETLAELEHAFKFNDAVLRHLTIKMKKAVTTPSPM
                     MKEEKSRSLSTASDDKPADSEAAAA"
     gene            11251..11523
                     /gene="priB"
                     /locus_tag="P5537_11960"
     CDS             11251..11523
                     /gene="priB"
                     /locus_tag="P5537_11960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004291713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of RNA
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal replication protein N"
                     /protein_id="HRV78799.1"
                     /translation="MAEVLPLRRTPAGIPVASCVLAHESKQVEAGLTREVSVEVQAVA
                     LGDLAGVLAAAVPGCALRATGFLAAKSLRSRSPVLHLNTIEFLEGN"
     gene            11526..11801
                     /gene="rpsR"
                     /locus_tag="P5537_11965"
     CDS             11526..11801
                     /gene="rpsR"
                     /locus_tag="P5537_11965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HRV78800.1"
                     /translation="MAFKPKSKFKKKDDRGGRGLFKRRKFCRFTAEKIEEVDYKDVDI
                     LKDFITENAKIMPARITGTKAGYQRQLSVAVKRARFLALMPYTDLHQ"
     gene            11817..12266
                     /gene="rplI"
                     /locus_tag="P5537_11970"
     CDS             11817..12266
                     /gene="rplI"
                     /locus_tag="P5537_11970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004291709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HRV78801.1"
                     /translation="MQIILLEKVVNLGGLGDVVKVKDGYARNYLIPQGKAKRATQANL
                     AEFEARRAELERAQAEKLAAAQELAGKLEGVSVEVARKAGMDGRLFGSVGNADISEAL
                     AAKGFDIDRSAIRMPDGPLKQVGETSLEVSLHADVLASITVVVAAEQ"
     gene            12407..13807
                     /gene="dnaB"
                     /locus_tag="P5537_11975"
     CDS             12407..13807
                     /gene="dnaB"
                     /locus_tag="P5537_11975"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HRV78802.1"
                     /translation="MSSASSRFSDFSADPQLAQIKLPPHSLEAEQSLIGGILLDNQAW
                     ERVADLVNEADFYRDDHRRIYRHITKLIDQGRPADAVTVFESLEKNGEAEQAGGLAYI
                     AELANNTPSAANIRRYAEIVRERAILRKLVAVGDEIAASALSPSGKDAKALLDEAEAK
                     VFEIAEAGARHASGFVSIQPILKQVVDRVQELYDRDNPSEVTGVPTGLVDLDDKTSGL
                     QPSDMIIVAGRPAMGKTTFALNLAEHIAIEQRLPVAIFSMEMPGTQLATRFISSVGRI
                     DMQKIRSGRLTDDDWQRLTMAMGKLYDAPLYIDETPGLNPIDLRARARRLARQCGRLG
                     LIVIDYLQLMSGTREGDNRASELSEISRSVKSLAKELNVPIMALSQLNRSLEQRPNKR
                     PVMSDLRESGAIEQDADIIMFIYRDEVYNPDSPDKGTAELIIGKHRNGPTGTVRLTFI
                     GENTRFENYAAAPGMY"
BASE COUNT         2208 a         4587 c         5152 g         1954 t
ORIGIN      
        1 gcgaagccga gcgcgggcgc ggcgatgtgg atgccgatgc gccagccgcc ctcgacgcct
       61 ccaccaccga gatcgacgac gccttctcgg tggtggaggc gtcgtcgatc gagaacgcgg
      121 cgacctcggc gcgcggcagc gcggtgggga gcacgggcac gtcgatcgcc gggaatgcgg
      181 tgccttccgg gaagtgctcg aagaggaagc ggttgtagtg gaagtcgtag ctcgacgcga
      241 gtgcgccgca cgccagcagc aggcgcgcgg ccgacagccc gctgtcgacg caggcggcct
      301 cgagcgcctt gatctcgggg cggttgcggt cggggcgata gagcgcctgc ggcagcaggg
      361 cggcgagttc gggcggcagg cgcccggcga cgagctcggt gcgcatgtgc tcgatcgcgg
      421 cggcctgctg gcgcttcttc tccaggccgg cgagcgcggc ctgcaggatg tcggcggggg
      481 ccttgcggaa gcggccgcgt cccttgcggt ggaaccagat cggcgccgag tgcaggcgaa
      541 gcagcagggc ggccgattcg accgcggtgg gcgcacggcc ctggtattcg gcggcgaagt
      601 cggcgaaggc gaattcgtcg tcgctgcaga cctcccagag gaactcgacg tccagccctt
      661 cggcctcggc ctcggcgcgc gcgagcaggt cggacggccc gggctcgcgg aattccatca
      721 gcacatgggc acgcttgagc ttcacccgct tgccgtgggt gttctcgacc tgcagcgtgg
      781 cgtcgttatc ggcgaggatg gtcccggcct tgaaggcccc gtcctcttca tacagcacga
      841 acatcggcat ccgcctgaag aaagcaagcg cgctagttta ctggattcgg gccgccggcc
      901 ctatcgcggg gtgcgaatgg aaggcgatgg ggtgcggggg cgatccggcg ggactccggg
      961 ccggcgtagc tcccgatcgg cgcaactcca atccggcggg actccaatcc ggcgcgactc
     1021 cggtctggcg cgactccggt ctggcgggac gccggtccgg ccgcggggcc ggggtggtgg
     1081 gcgccgcctg ccgtcgcggc ccctcgcgtc gctcggggct accctcggcg gcggacgccg
     1141 cgggggcggc gacgcaaact cgtcgctgcg ctcctcggac atgcgtcgcc ttgtttcccc
     1201 cgcgacgccc tccacctcgg cgctcctgaa gttggccccc accaccccgg ccccgcggcc
     1261 tcgcggattc ggtgctcgag gcgtgttgcg ttccgggcgc ttccaccgaa ggccttggtc
     1321 tgcgacggtt ctgtaggagc ggcggcagcg gcgaatatgg cgcatggaat tcgcgccgcg
     1381 gcagcgtcac cgccgcattc gcgcctgccg gcgctcctgc agaaaccgac gcggtccggg
     1441 cccatgcagg agcggcggca gccgcgaata cggcggtgcg gtggcgacgg gcgttgtcgt
     1501 gcgcggaggc gccgcaatcg cgcctgccgg cgctcccgga atccgccgtg agggcagcgc
     1561 tcttcccgga tccccgtggc gagcatcgga cggtcgggtc gaagtgcttc cttcagcgcg
     1621 cgcgccgggc tgcctgccgc ccggcgcgga ccatgtccgc cgaatacacc gcgagcgcga
     1681 gccagatgag cgcgaagccg acgagctggg tggtgtcgaa gggctcgcgg aagagcagca
     1741 ccgccaccag gaagttcagg ctgggggcga tgtactgcag gaagccgacg gtggccagcg
     1801 gcaggcggcg ggcgccgacc gcgaacagca tcagcgggat ggcggtgatc acgccggtga
     1861 gcggcagcag ccactcggcc gggttgccgc tgccgaaggc gaggctgccc tgcgcgtgca
     1921 gccacagcag ccaggcgagc gcgagcgggg cgaccaccag ggtctcgatg aacaggccgc
     1981 ccacggcgtc caccggggcg cgcttgcgca gcaggccgta gagcccgaag gtgccggcga
     2041 ggaagagcgg gatccacggc aggctgccga gctgccagac ccgccaggcc acgccggcgc
     2101 aggcgatcgc caccgccgtg gcctgcagcg ggcgcaggcg ctcgccgagg aagatcgcgc
     2161 ccagcgccac gctgaccagc gggttgatga aatagccgag gctggcctcg agcaggcgac
     2221 cggcgtcgat cgcccagatg aagaccagcc agttgctgct ggtgagcagc gaggtgagcg
     2281 cgagcagggc gagcaggcgc ggctgccgca gcacggctcc cacgcgctcg aagccgccgg
     2341 tgaagtgcag cgtggccagc atcagcgcga gcaggagcgc cgaccacagc acgcggtggg
     2401 cgacgatctc gaacgggggg acgctgccga gggcgcggaa gtagagcggt gccagacccc
     2461 aggttacgaa ggcggcgagc gcggcgaaca tgccctggcg ggcggcgcgg gcgttggctt
     2521 cggcggggga ggaggggagt gccgcggcgc gggcgcgggg ctggggggcg gacaagtcgg
     2581 gatccgggga acgaatgggg ggaggggaga aggctgaggg cggaaggccg cggtaagggc
     2641 ggaacggcga gacaaggacg gactgaggcg gaaggtcgag gtgccgggaa gtcgggagaa
     2701 aggacccggg ccgcccgcgc gcggcgtgga cggccagggt cgctcgggcg aggatcagtc
     2761 cggtcggcgg gcgctcgcca ccagggtccg ggccggcatg aggaagccgc cgcggccgtc
     2821 gtcgcagcag tgatgggcga ggtcgtccgc gaccgccgcg cgcagttgcg cctgtaccgg
     2881 ctcgggcagg cggccgagcg cctccgcagc gccgccggcg aggtcgagga aggcctgcca
     2941 gtaggcatcg gcgtcggcga agtggcagga gaacgcgcac gggcggatgt cgatgtcgtc
     3001 gaaaccggcg gccgcgagcg tggcggagag cacttcgggc tcgccgtagc ggaacaccga
     3061 cgggcgtgcc accttgggcg gcggcagcag gcgggcgatg gtgtcctggg cgcggtggat
     3121 cagcggcacg gtctcgcgcg cgccccagac cgacagcgcc acccggccgc cgggcacgag
     3181 cacgcggtgc atctcggcaa gcgcgcgctc ggggtgcggg aagatgaaca gcgcgagccc
     3241 ggcgagcacg cggtccatgc aggcatcggc gaggcacagg tgttcggcgt cggcggcggc
     3301 gaagcagggg gtgtcggcgt gttcgccgca gcggcgcgcg ccctcggcga gcatgccctc
     3361 ggcgatgtcg gtggcgagca cgctgccgcc ggggacgacg cgcagcgcgg cctggccggc
     3421 gagcaggccg gggccgctgg cgaggtcgag cacgcgctga ccgggagcga gcgcggcggc
     3481 atcgagcagg gcttcggcga ggtcggcgcg caggtgggcg ccttccgcgt agcgcgcggc
     3541 aatgcggttg aagccggcgc gctccatggc cttgaagcgg cgggcgtcga agccgggctg
     3601 ggcgggatcg ttgggatggc tcatcggctg cgctccgagt gcggatgggt cagggacggg
     3661 gggcggcggg cttggcgcca ccgagccgcg cgagaggggc gtcgccaagt cccgcgtagg
     3721 cgatcacctc gtcgaggtag tcgttccagc gtgagaagcc gtgttcgccg ccttcgagca
     3781 cggtctggcg ggcaccggcg tatctttcca ccgcgtggcg gtagtcgagc acctcgtcgc
     3841 cggtctccac catcagccag aagcgctgtg gccgggtgat cgtcggcacc tcgagcgcgc
     3901 gcagttcgtc gatgtggccg cgggtgaact cgaagcgctc gccggtgtag aggttgtcct
     3961 gcatgccgac ataggcctcg agcgacagcg gtgcgaccac cgccggattg accagcaccg
     4021 cgcgcaggtc gtggcgttcg gcgagccagg tggcgtagta gccgccgagc gagctgccga
     4081 ccaccgtggg atccaggccg gcggcgcgcg cgcgcgcgat ctcgccctcg gcgagcgcga
     4141 tcgccgcgcg cggcgacacc ggcagctgct cgcaccagaa gcgctcggcg aggccgcgct
     4201 cggtcatgcg cgccttcagg gcgcgcgcct tgatcgatgc cggtgcggaa cggaaaccgt
     4261 gcaggtagat gatcatcttg cgtgcctcga tcagggctcg gaccactcga cccagccgaa
     4321 gtaccaggtc gcgagcacga agatgccgaa ggcgatgcgg taccaggcga agacgatgaa
     4381 ggtgtggttg gagatgaact tgatgaagct cttcaccgcc cacatcgcgg cgacgaagga
     4441 ggcgacgaag ccgaccgcga acaccggcag gtcctcgagg cgaagcagcg tccagttctt
     4501 gtacaggtcg taggcggtgg cggcgaacat ggtcgggatc gccaggaaga aggagaactc
     4561 cgccgccgtc ttgcgcgaca ggccgaagat cacgccgccc atgatggtgg cgcccgagcg
     4621 cgaggtgccc gggatcatcg ccagcgcctg ggcgaagccg accttgaggg cgtcggtcca
     4681 gcgcatgtcg tccacgtcgt tgatgcgcgg gtggtaggcg cgcttttcca cgtacaggat
     4741 gatcaggccg ccgaccacga gcgcggtcgc caccgtgatc gggttgaaca gcaggccctt
     4801 gatcgtggag tggaacatca ggccgaggat ggccgcgggc aggaagccga tgaacagcag
     4861 ccacacgaag cgctgcgcgc tcggttcggt agtgaccccg cccgcgacct tgatcaggcg
     4921 ctcgcgatag tcccagcaca cggcgaggat ggcggcgagc tggatgacga tcttgaacac
     4981 cttgctggtg tcgtcgttgt agccgagcag gtcgccgatg atgatcaggt ggccggtgga
     5041 ggataccggc aggaattcgg tcaggccttc gacgatgccg aggacgagcg cgacgagaag
     5101 gagggagagg tccatgcggc ggggctgtgg gtatgggagg aggaggcggg attatagccg
     5161 gcggaatgtt gcgccgcggt aggggtggcg ctcacgccgc cgtcatcgtc tcgagggtgg
     5221 cgaggaagtg cagggcatgc tcgcggtcgg cgccgcacat ctcggcgccg ggcttcaggc
     5281 tggaacacac cgccggccgg cgcggatcgc cgaacaggcg gcagtgcccg gattcgtcga
     5341 gctgcacgca gcgcacgccc gccggcttgc cgtccggcat gcccggaatg ggcgaggaga
     5401 tcgacggcgc gatgcagcag gcggcgcaac ccgggcggca gtccatgcct cagccggccc
     5461 gcggggccga ccaccaggcg aggatggcgt ccagtgtggg ttcgagcagc acgccctcgc
     5521 cgccggtgaa ttccttccac tcggcgagga agcgctcgcc taccgcggtg aggaggggga
     5581 cgccggcgac gacggtctcg gccatctcgt cgcgcaggcc ggagccagcc acctcctggg
     5641 cgccgaactt gttgatgatg atcagatcga cgccgcgtgc gatcgcgccg cgcaccgcca
     5701 tcgagccgcg cgcgagcgcg tccgggtcga cccggcagga gatcgagccg cggccgagct
     5761 cctgtgacag cgggatgctc tcgccggtct cgaggttctc gagctgcatc gcgcaggggt
     5821 cctcgatgac cgttgcgatg tcgtgctgca gcacgccgcc gaggcgcacg ccgcgctcgc
     5881 ccagagcgcg cgcggcgcgc gcgagcaggg cctcgatgtt gtcggtgggt ttgtagacga
     5941 cggcggcgat ggcgtgtgcg ggcatggtcg ggctcggcgg gcggctcgtt cgtggatggg
     6001 catcattgtc gcactgcggc gccaacaagg cgaagatgcg ggagataatg cgcggcccga
     6061 cgaagccgaa atcgatccat gagggctgaa cacaagggtg agcgccgccc gtccgcgctg
     6121 ccgaacttcg acgactgcct gagcgtcgat cgcccgcgcc tgcgccgcat ggcgcgcgac
     6181 ctctctcggc cgccgcgcgc cgacgagcgt gcggcagcgc agcgcctgcg cctgcaggcg
     6241 gacttcgacg cgctgctcga gcgctcgcgt gcggcattgc tcgcacgccg cgcggcgctg
     6301 ccggtgcccg actttccggc agaactgccg gtgtcggcgc gtcgcgacga gatcgccggg
     6361 gccctggcag cgcatcaggt catcatcgtg tgcggcgaga ccggctcggg caagaccacc
     6421 cagctgccca agatcgcgat gacgctcggt cgtggcgtcg ccggcctgat cggccacacc
     6481 cagccgcggc ggctcgccgc acgcgccacc gccagccgca tcgcgcagga gctcaagagc
     6541 gcgctcggcg aggtcgtcgg ctacaagatc cgcttcaccg acaagaccag cgagcgcagc
     6601 cacgtcaagc tgatgacnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnccg
     6721 gtggagagcg aggacgtcga cccggcggcc gcggcgcgcg cgtccgcgag aggtgggaag
     6781 gagggcgaca aatcgagagc gggtggcagg gacaagagcc gcgacctgat ggacgcgctg
     6841 gtcgacgcgg ttgacgaggc gcagcgctgc ggcccgggcg acgtcctcgt cttcctgccc
     6901 ggcgagcgcg agatccgcga ggccgccgag gcgctgagga aggcccatca cctgcccggc
     6961 accgagatcc tgccgctgtt cgcgcgccag tcggcgcagg agcaggcgcg cgtgttctcg
     7021 gcctcgaacg ggcgcagggt ggtgctgtcg accaacgtcg ccgagacctc gctgaccgtg
     7081 ccgggcatcc gctacgtggt cgacacgggc ctggcgcgta tcaagcgcta ctcgccgcgc
     7141 aacaaggtcg agcagctgca ggtcgagaag atcgcgcagt cggccgcaca gcagcgcgcc
     7201 gggcgctgcg ggcgggtgat ggacgggatc tgcatccgtc tgtacgacga ggatgatttc
     7261 aaccgccgtc ccgagcatac cgatcccgag atcctgcgct cctcgctcgc cggcgtgatc
     7321 ctgcgcatga aggccttgaa gctcggtgcg gtggaggact tccccttcat cgacgcgcct
     7381 ggctcgcgcc tgatcggtga cggctacgcg ctgctcgccg agctcggcgc ggtcaccgac
     7441 gacgacgagc gcaagctgac gccgaccggc attgaactgg cgaagctgcc gctcgatccg
     7501 cgcatcggcc gcatgatcct cgccgcgcgc gaccgcggcg cgctcgccga gctgctggtg
     7561 atcgccgccg cgctgtcggt gcaggacccg cgcgagcgtc cgcaggacag cccgggcgcg
     7621 gccgaccagg cgcacgcgag gtttcgcggc ggcgagcagg accagaagtc cgagttcctg
     7681 tggtactggc acctgtggaa ggcctgggac gaggtgcagc gccacgagac ctcgagcaag
     7741 cagaaggcct ggtgcaagaa gcacttcctc aactacatgc gcatgcgcga gtggcgcgac
     7801 gtgttcgccc agctccatac cctgtgcgcc gagcacggct ggaaggagaa cgcgcagccg
     7861 gcgaactacg aggcgatcca caaggcgctg ctcgccggcc tgctcggcaa catcggctgc
     7921 aaggcggatg agggcgagtc ggcgggcaag ggcccgcagg ccggctccta cctaggcgcg
     7981 cgtggcatcc gcttctggcc gcatccgggc tcggcgctgg cgaagaaggc cggcaagtgg
     8041 atcatggccg ccgagcaggt cgagacctcg cgcctgttcg ggcgctgcat cgcgcgcatc
     8101 gagccggagt gggtggagga ggtcggcggc cacctggtca agcgccaggt cttcgagccg
     8161 cactggtcga agtcctccgg tgcggtgcgc gcctgggagc gcggcacgct ctacggcctg
     8221 gtgatctacc cgcgccgcgg cgtggcctac cgcgacatcg accccgcgct gtgccgcgag
     8281 ctcttcatcc gcgaggggct ggtgcagggc gagatcgccg aggggccggc gcgcgcgatg
     8341 gccttcctgg cccacaacca gcgcctggtg gcggagatcg agcgcctcga gcacaagtcg
     8401 cgccgccccg acgtgctggt ggacgagacc ctgatcgagg ccttctacga cagcaagctg
     8461 cctgcggacg tgtgtgacgt cgccggcctg gaggcctggc gcaaggcggc ggagaaggcc
     8521 gagccaaagc tgctgcacct gtcgcgcgag cagctgatgc gccacgaggc cgagggcgtc
     8581 accaccgacc gcttcccgcc cgcgctggag gtgctcgggc agaagctcaa actcacctat
     8641 ctgcaccagc ccggcgaggc cgacgatggc gtgacgctcg ccgtgccgct ggccatgctc
     8701 aaccaggtcc ctgcaaaccg ctgcgagtgg ctggtgccgg gactgctgga ggagaaggtc
     8761 gcggcgctga tgaagaccgt gccgcagaag catcgccacc gcctgcagcc ggtggccgag
     8821 agcgcggcgg ccttcatggc ggccttcgag gccggcgagt tcgacgccga cgagccgctg
     8881 ctgaagatgc tgcagcgctt cgtcgaggag cgcgtgcagt tgaagctgcc gctggagagc
     8941 ttccgcgccg agaacctcaa gccgcactgc ttcatgaact tccgcgtgat cgacgagcac
     9001 ggccgggtca tgggtcagtc gcgcaacctg atggagctgc gcgcgcgctt ccgcgagcag
     9061 gtggcggcgc gcttctcggc ggcgaagatc ggcggcgcgc tcgcgggcgc gctgtcggcg
     9121 gcgggcgtcg cgggggcgga ggcggggcag ggccgtggtg agggcgcgga cgggatggcg
     9181 cgtcgcgcgg gtgctgccga ggcggctggc gcggcggcgg cggcgggcac tgctcagccc
     9241 gggcgcaagg ggagcggcaa ggcggcgggc gacgccccgg ggcgcggcgc cgcagcggcc
     9301 gagctgccgg cgcaggcgct gtccggcttc tccgcctgga ccttcggcgc cctgcccgaa
     9361 ctgctcgagg tgcgcgtcgc cggccgcgag gtgatcggct tcccggcgct gcacgacgac
     9421 ggcgacagcg tctcgctgcg ccctcacgac acgcccgagg aggctgcgcg tgtgcatcgc
     9481 cgcggtctcg cccgcctgtt cgcgctcaac ctcaaggatc aggtgcgcgc ggtcgagcgc
     9541 ctgcccggcc tgcgcgagct cgcgctgcag tacatgagct tcggcaccga ggccgagctc
     9601 aaggcccgcc tcgtcgaggc gacgctgagc cgctgctgtc tgctcgagcc cttgccgacc
     9661 gatgccgatg cgttcgcgcg gcgttgcgcc gaggccaagt cgcgggtgag cctggtcgcg
     9721 caggagttca tgcgcctgac cggccagctg ctggtggaac atgcggcgct gcagaagcgc
     9781 ctgtccgggc tgaagacctt ccccgaggtg gtcgccgatc tccaggccca gctcggcgcg
     9841 ctgctgccga aggattttct cgtcgctttc gagtgggaca agctcgcgca cttcccgcgc
     9901 tacctcaagg gcgcctcggt ccggctcgac aagctccgca acaatccggc gcgcgacgcg
     9961 cagtcgatga gcgagtggaa gcagctcgcc caggcctggg agcgcgagcg cctcgcgcgc
    10021 cgacgggccg gggtcgagga cccggcgctg gaggagtttc gctggctgct ggaggagctg
    10081 cgcgtcggcc tgtacgcgca ggaactgagg acgccgatgc cggtgtcggt caagcgcctg
    10141 cagaagatct gggagagccg gccgcgctga ctcgcgcggc cggctcggca gggtgcgggg
    10201 ccaggggagt ggctccgcac cctgcgaacg gacagggaac gggcgtgttc agcgcagcgg
    10261 aatcaccagc ggcgggatat ccacgccgat caccacggcg ggcgagcggc tgtagctgta
    10321 cgaacggtgg gggcgctcgt agtagtggtt gtggatctcc ggttcgcggt agtagcgcgg
    10381 gcgttcgcgg atgatgacct tctcgcgata cacggtgcgc tcgtcccagt ggcgacgatg
    10441 cttgtgatcg tgcttgtagt ggtgcttgtg gtggccccag cgcgggccac ggtcgtcgcg
    10501 gtccgcatgc gcggcgggcg cggcagcggc aaggatgccg ccgcagagca gggcggtgac
    10561 gatcttgcgg gtcagggtcg tgttcatggt ctgcctcgtt cgatttcttc gttgcagggc
    10621 agggccccgg tgatccggat actaggcgag gcgtgcgccg cgaggcagtc gcagagtgta
    10681 agcgggcttt tgtaactgcc atcccggttc gcggtttttc agtgcctttg atttttcggg
    10741 atttcttgtt agactggcga gcttcccttg ctccaccgga ccgcatgccg gggggctgca
    10801 acaaccaacc gcaaggagtt tgcatgcgac attacgaaat cgtcttcatc gtgcacccgg
    10861 atcagtccga gcaggtgccg gcgatggtcg agcgctacaa gtccatcgtg accacccgca
    10921 acggccagat ccaccgcctc gaagactggg ggcgccgcca gatggcctac ccgatccaga
    10981 aggtgcacaa ggcccactac gtgctgatga acatcgagtg cgacggcgag acgctggccg
    11041 agctcgagca cgcgttcaag ttcaacgacg ccgtgctgcg tcacctcacc atcaagatga
    11101 agaaggctgt caccacgcct tcgccgatga tgaaggaaga gaagtcgcgc tccctgagca
    11161 ccgcttccga cgacaagccg gccgacagcg aagctgctgc cgcctgagtt gcctgagccg
    11221 ggtctgaacg aactgcgcct cgatgcgcgc gtggccgaag tgctgccgct gcgtcgaacc
    11281 cctgccggaa taccggtcgc cagctgtgtg ctggcgcacg aatcgaaaca agtcgaagcg
    11341 ggcctgaccc gcgaggtttc ggtggaagtg caggcggttg cgctgggcga tctggcgggc
    11401 gtgctggctg cggcggttcc gggatgtgcg ctgcgcgcca ccggattcct cgccgcgaag
    11461 agcctgcgca gccgtagccc ggtcctgcac ctgaacacaa tcgaatttct cgaaggaaac
    11521 tgaaaatggc cttcaagccc aaatccaagt tcaagaagaa ggacgaccgt ggtggtcgtg
    11581 gtctgttcaa gcgtcgcaag ttctgccgct tcaccgcgga gaagatcgag gaagtcgact
    11641 acaaggatgt ggacatcctg aaggacttca tcaccgagaa cgccaagatc atgccggcgc
    11701 gcatcaccgg caccaaggcg ggttaccagc gtcagctgtc ggttgcggtc aagcgtgccc
    11761 gcttcctggc cctgatgccc tacaccgacc tgcaccagta agaggagaac ggaaacatgc
    11821 agatcattct tctcgagaag gtcgtgaacc tcggtggcct cggcgacgtc gtcaaggtca
    11881 aggacggcta cgcccgcaac tacctgatcc cgcaaggcaa ggccaagcgt gcgacgcagg
    11941 ccaacctggc cgagtttgaa gcgcgccgtg ccgagctcga gcgtgcccag gccgaaaagc
    12001 tggccgccgc gcaggaactg gccggcaagc tcgaaggcgt cagcgtcgaa gtcgcccgca
    12061 aggccggcat ggacggccgc ctgttcggct cggtcggcaa cgccgacatc tccgaggcgc
    12121 tcgccgccaa gggcttcgac atcgaccgct ccgccatccg catgccggac ggcccgctca
    12181 agcaggtcgg cgagacctcg ctcgaggtgt cgctgcacgc cgacgtgctc gccagcatca
    12241 ccgtcgtggt ggctgccgag cagtaatcgc gttccggcgt gaatcacgaa aagggctgcc
    12301 gctggcagcc cttttcgttt cctgtgcccc cgaggcgcgt ccccttcacc aacgtcccgc
    12361 ggtccggctc gctacaatgc gcgatccggc cccgatggtg catccgatga gctctgcgtc
    12421 ctcccgcttc tccgatttct ccgccgatcc gcagctcgcg cagatcaagc tgccgccgca
    12481 ttcgctggag gccgagcagt cgctgatcgg cggcatcctg ctcgacaacc aggcctggga
    12541 gcgcgtcgcc gatctggtca atgaggccga tttctatcgc gacgaccatc gccgcatcta
    12601 ccgtcacatc accaagctga tcgaccaggg gcggcccgcg gatgcggtca ccgtgttcga
    12661 gtcgctggag aagaacggcg aggccgagca ggctggcgga ctcgcgtaca ttgccgagct
    12721 cgccaacaac acgccttcgg cggcgaacat ccggcgctat gcggagatcg tccgcgagcg
    12781 cgcgatcctg cgcaagctcg tggcggtggg cgacgagatc gccgcgagcg cgctcagccc
    12841 ctcgggcaag gacgccaagg ccttgctcga cgaggccgag gccaaggtct tcgagatcgc
    12901 cgaggcgggc gcgcgccacg ccagcggctt cgtgtcgatc cagcccatcc tcaagcaggt
    12961 ggtggatcgc gtgcaggagc tctacgaccg cgacaacccc tccgaggtca ccggcgtgcc
    13021 gaccggcctg gtcgacctcg acgacaagac ctccggcctg cagccatccg acatgatcat
    13081 cgtcgccgga cgtccggcga tgggcaagac caccttcgcg ctcaacctcg ccgagcacat
    13141 cgcgatcgag cagcgcctgc cggtggcgat tttctcgatg gagatgccgg gcacccagct
    13201 cgcgacgcgc ttcatctcct cggtcggccg catcgacatg cagaagatcc gcagtggccg
    13261 cctcaccgac gacgattggc agcgcctgac catggcgatg ggcaagctct acgatgcgcc
    13321 gctgtacatc gacgagacgc cgggcctgaa ccccatcgac ctgcgcgcgc gcgcgcgtcg
    13381 cctggcacgg cagtgcggca ggctgggcct gatcgtgatc gactacctgc agctgatgag
    13441 cggcacgcgc gagggcgaca accgtgcctc cgagctgtcg gaaatctcgc gctcggtgaa
    13501 gtcgctcgcc aaggagctga acgtgccgat catggcgctc tcccagctca accgcagcct
    13561 ggagcagcgc cccaacaagc gcccggtgat gtccgacctg cgcgagtccg gcgccatcga
    13621 gcaggacgcg gacatcatca tgttcatcta ccgcgacgag gtgtacaacc ccgactcgcc
    13681 ggacaagggg acggccgagc tgatcatcgg caagcaccgt aatggcccca ccggcacggt
    13741 gcgcctcacc ttcatcggcg agaacacgcg cttcgagaac tacgccgcag ccccgggcat
    13801 gtactgagcg ccatcgcagg aggcgccggg ctccgaggct tctgcagggt tttgcgctgg
    13861 ggcgaacccc ggctcccggt ctgacgacag gcgtcggcgg ggtcgagcgc gcgggcgttc
    13921 gcgcccaccg gcgcggccct gcctgaagcg gttcctgcag gagggccggc aggcgcgaac
    13981 ggcggctgca gcgttctgga t
//
LOCUS       DAOTIN010000083        13974 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_5250_length_13974_cov_9.151376, whole genome shotgun sequence.
ACCESSION   DAOTIN010000083 DAOTIN010000000
VERSION     DAOTIN010000083.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 13974)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 13974)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13974
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5250_length_13974_cov_9.151376"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(7..603)
                     /locus_tag="P5537_11980"
     CDS             complement(7..603)
                     /locus_tag="P5537_11980"
                     /inference="COORDINATES: protein motif:HMM:NF019349.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HRV78803.1"
                     /translation="MTNESLFQPVRTRRGFEAVCDRIREQLMSGELKPGDQLPGEREL
                     AERFGIGRAAARDALRSLEVSGVVEARKGIQGGFFIRNGGSGGLAQTVQDMVSLAQAS
                     LENVMEARTEIICVAIRLACPRATNEEFDTIQRDIDLHADLFRLGRASRNTQSVIEFY
                     RLIAQATHNPLVLMMVDALSEVYRGLLVFSAISDGTKS"
     gene            669..1829
                     /locus_tag="P5537_11985"
     CDS             669..1829
                     /locus_tag="P5537_11985"
                     /inference="COORDINATES: protein motif:HMM:NF012656.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HRV78804.1"
                     /translation="MDLDLTPEQRAFRDEVRTFIREKLPSEIRERLRAGHPPRKQDTV
                     AWQRILNERGWAAPHWPKRYGGADLGPMERLILLDETYRAPAPLPQVLNVGMLGPVLM
                     KFGTPAQCDHFLPRLANLDIWFCQGFSEPGSGSDLASLRTAARREGDHYIVNGQKIWT
                     TTAHLADWVFALVRTDTEARKQEGISFLLIDLRTPGITIRPIHSIDGEHHLNEVFFDE
                     VRVPVGNLVGQENKGWDCAKFLLSNERTGIANVGLCRERLDYARELAGRYTQAGKPLL
                     DDPKLRADIAMLEAETRALEITNWRFLLTDSEQKRLPAFASVLKLKGTELQQEINALL
                     ARIVGPGGLERRSADEVTHGPIVPRYFYSRAASIYGGTTEVQKDILAKAIVG"
     gene            1837..2973
                     /locus_tag="P5537_11990"
     CDS             1837..2973
                     /locus_tag="P5537_11990"
                     /inference="COORDINATES: protein motif:HMM:NF012656.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HRV78805.1"
                     /translation="MNFELNEDQAALAESLSRLLADRYGFEKRRALTASGAAHDEKTW
                     AGLAELGLTALPVPEALGGFGGGARDLLPAMQAFGRSLSMEPFLASAVLAGTALRLGA
                     DEAMQTRLLPGMASGEIVSAWAHDEPAGRHAPLWVETRAERKDGGWKLDGIKSNVPAG
                     GLARYFVVSARIAGAPADANGCALFLVDAKDAGVALREFRLVDDTAAGELVLTQAAAQ
                     PLANPEDSTRTRLAIQGTVAAGIAAVCADMSGAAQAAFDLAMDYLRTRKQFGRLIGEN
                     QALRHRASEMLVSLEMARSMAMAAAVAADDASAEDSAPDLHRAKLSVARNARNVALGA
                     IQLHGGIGMTEEYAVGHYLRRIHVLDQMFGDADAHAARLAAALL"
     gene            2985..4517
                     /locus_tag="P5537_11995"
     CDS             2985..4517
                     /locus_tag="P5537_11995"
                     /inference="COORDINATES: protein motif:HMM:NF009071.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HRV78806.1"
                     /translation="MSITPMIYLDGRGVTRDEVLRVAQQAATGFEQLGVSEGDTVALL
                     LRNDFAFFEVQQAAAAVGAYGVPLNWHGRTEEVIYVLEDAKPKVLVAHADLLAPIRAL
                     VPAGIRVFVVPTPPEIQQRYGVSTELARPLPGDTVWREWAERFEPLQAPPRRARATMI
                     YTSGTTGHPKGVKRQPATPEESKAYVELFASVYGLKPGMRALVCGPLYHASPNGYGRQ
                     ALMTADVLVLQSKFDPEETLALIEKHRIDNAVMVPTMFVRMLKLPPEVRNRYDVRSLR
                     WVTHTGAPCPREVKKDLMDWWGPVVYEGYGGTEVGTVTLATPQDWLEHPGCVGMPTPG
                     TRMAFYDEEGNRLPEGEIGEIFARVPAYPDFTYLNHEEKRKSVERDGLISLGDVGYMK
                     EGRLYLCDRRSDMVIFGGTNIYPAEIEMVLTQCPGVKDCAVFGIPDDDFGESLAAAVE
                     RMPESQVTPEEIRSYLLERLAKFKVPKRIDFHESLPREDSGKIFKRRLRDPFWQNAGR
                     KI"
     gene            4528..4884
                     /locus_tag="P5537_12000"
     CDS             4528..4884
                     /locus_tag="P5537_12000"
                     /inference="COORDINATES: protein motif:HMM:NF012596.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase-related protein"
                     /protein_id="HRV78807.1"
                     /translation="MGKWLQSNEHLTFEVRERVARITLNRPDRRNALSWEMLSELRAA
                     LLEADDLRSVSVIVLGGAGPDFCAGYDMKSAYARYAAEGDAALAPSARHRRHRSRGGS
                     THRARSSAPRRAHLLS"
     gene            4991..>5712
                     /locus_tag="P5537_12005"
     CDS             4991..>5712
                     /locus_tag="P5537_12005"
                     /inference="COORDINATES: protein motif:HMM:NF015366.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter substrate
                     binding protein"
                     /protein_id="HRV78808.1"
                     /translation="MKFTRRQTLAAALGSLGAGVLPRAQAQTQPFPSQVIKFVIPTPA
                     GGDHDTMMRIIGQKLTDAWGQPCIVESRSGASGAIAAATVSQAPADGYTVLLGYSALL
                     SNTVLMPKPGYRLEDLQPVGMLALTPIAFGVRESLPASTLKQYVALAKTRPGKLSYGS
                     YGPGSGGHFVGELFNMAAGIDTVHVPYKGQPPALQDLIGGRIDAAVASLGRVNRYPGK
                     IKPLAVASATRFPSYPDVPTFA"
     assembly_gap    5713..5812
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(5813..6478)
                     /locus_tag="P5537_12010"
                     /pseudo
     CDS             complement(5813..6478)
                     /locus_tag="P5537_12010"
                     /inference="COORDINATES: protein motif:HMM:NF024744.2"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
     gene            complement(6475..7350)
                     /locus_tag="P5537_12015"
     CDS             complement(6475..7350)
                     /locus_tag="P5537_12015"
                     /inference="COORDINATES: protein motif:HMM:NF013722.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="HRV78809.1"
                     /translation="MIDYEKTKAWRSDPVRHTYTERDTILYALGVGFAADPLVLEELR
                     FVYEKELQAVPTMAAVLASPGFWMRDRKELGIDYLKLVHGEQGVTIHSPLPAAGTLIG
                     QSRVTRIVDKGEGKGATMHVEKTLTDEASGRPVATAEMVAFLRGDGGFSKNGGGDEPV
                     PAAPATPDAAPEVTIEMPTRADAAVLYRLSGDINPLHIDPAVAAKAGFPRPILHGLAT
                     YGNACRGILAKFCGHDASRMKSIRARLTSPVYPGETLVLDCWRLGSEEIAFRASVKER
                     GVQVLANGRAVLGAR"
     gene            complement(7355..8152)
                     /locus_tag="P5537_12020"
     CDS             complement(7355..8152)
                     /locus_tag="P5537_12020"
                     /inference="COORDINATES: protein motif:HMM:NF012596.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HRV78810.1"
                     /translation="MTGDSVLFERADGVAVLTLNRPSAKNAIDIPTTDALVAALRGLR
                     AADDIRAVVLAGAGGDFCAGGDVKGMADGASRTVEQRRAGMARYAELARALASLDKPL
                     IAAVDGVAFGAGLSMALYADIVLVSTRARLAMVFHRIGLVPDVGAWYQLPRVVGLQRA
                     KELIYSAREFGADEAVRMNIALEALAPEALMPRAMELARSLAGASPTAFSLSKRALAA
                     TLQSDLETMLDMEASSQAIALSSAYFREAIRRFAAKEPAQFCWPNKD"
     gene            complement(8154..8927)
                     /locus_tag="P5537_12025"
     CDS             complement(8154..8927)
                     /locus_tag="P5537_12025"
                     /inference="COORDINATES: protein motif:HMM:NF024950.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HRV78811.1"
                     /translation="MDPIVSLQGRTIVVTGAGQGIGKGIVELAIELGANVVAVDLNGQ
                     TLDAAVSPLPQARVLAVQGSVADPAVADRAVTEAVAKFGAVHGLVNNAGIIRPAMIDK
                     MTDQQWQEVIDVHLTGSFYWMRATGRHMVERSKGGERTGGSIVNISSEAGRRGSIGQI
                     NYAAAKAGMLGMTMTAAREWGRYNIRTNSICFGVVETPMTEVVRGEKFRDGMLAQIPL
                     GRWSTPGEVVKSVCFLLSDGSSYITGQHLGVNGGIHISL"
     gene            9004..10173
                     /locus_tag="P5537_12030"
     CDS             9004..10173
                     /locus_tag="P5537_12030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011239015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase domain-containing protein"
                     /protein_id="HRV78812.1"
                     /translation="MTIKRKACIAGAYEHPTRKAPDKTVAQLHAECARGALADAGLTL
                     QDVDGYFCAGDAPGLGANNMADYLGLTKLRHIDTTDTGGSAYLIHVSHAAQAIAAGKC
                     DVALVTLAGRPRSEGSSGVAPRLVTANTPDVPWEMPYSPVIVNMYALAAARHMHEYGT
                     TSEQLAWIKVAAAAHAQHNPNAMLREPVTVEEVLASPMISDPLHKLDCCVVSDGGGAL
                     VVVRPEIAARLKRPVVNILGAGETIKGQLGGHVDLTWSGAAISGPIAFKEAGVSPADI
                     QYASIYDSFTITVLMQLEDLGFCKKGEGGRFVADGNLISGVGTLPFNTDGGGLCNNHP
                     ANRGGITKVIEAVRQLRGEAHPKVQVPDCTLALAQGTGGLLGSRHGSATLIMERQ"
     gene            10177..10575
                     /locus_tag="P5537_12035"
     CDS             10177..10575
                     /locus_tag="P5537_12035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018989586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OB-fold domain-containing protein"
                     /protein_id="HRV78813.1"
                     /translation="MTTPYTERPLAPVTVDAATEHFWTQAKEGLLCTRRCTSCGEVHW
                     YPRALCPFCMGDTEWCSLSGLGTIYSVSVTRRAGPIAYAIAYVALDEGITLLTNIVDC
                     DFDDLKIGQRVEVTFKPAEGGAMVPMFKPA"
     gene            10587..11384
                     /locus_tag="P5537_12040"
     CDS             10587..11384
                     /locus_tag="P5537_12040"
                     /inference="COORDINATES: protein motif:HMM:NF012596.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HRV78814.1"
                     /translation="METLDFSVENAVGWIRLTRPEIHNPLDVPLRTDLMTVLEQVRND
                     PAVRVLVLNGGAGAFCAGGNLHALQEHANAGPAYWQRRINAGLRLTDDLLNVGCPVIA
                     AIDGPAIGAGFALALSADMIIASPRAKFAMAHLRLGLVPDLGALYLLPRVVGLQRAKE
                     LVFSTRDVSADEARELGIVMEVHASEALEARARDMAERMARAAPTAVALSKAMLNASL
                     DSDRQSAFALEAASQAAAFAAPEPAAQVEAILGKQRPAFSGLKYARG"
     gene            complement(11390..12226)
                     /locus_tag="P5537_12045"
     CDS             complement(11390..12226)
                     /locus_tag="P5537_12045"
                     /inference="COORDINATES: protein motif:HMM:NF013429.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HRV78815.1"
                     /translation="MSGNPRRREVRALTLGFLSLGANAAPLDVLSAAAEAGFGAVGLR
                     VSGRNPGDPWPQPNAEGDGLERIRARAEALSIRISSISGYYMSEKTSLSHLLANVEAA
                     RRVGAPLISQGCFEPDPSRVAELLRDYARAADDAGVRIALEFMPMSSLKTIADAQRVI
                     ADSGARNVGLLIDSLHLARSGAGGADVRALDARCIHLTQLCDAPAVRAAETTLFDEAM
                     SGRMYVGDGGLDLKGLVEALSPDAEIELETPVIADATLPGGERARRAAEKAMAFFVSH
                     FG"
     gene            complement(12223..13278)
                     /locus_tag="P5537_12050"
     CDS             complement(12223..13278)
                     /locus_tag="P5537_12050"
                     /inference="COORDINATES: protein motif:HMM:NF013530.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HRV78816.1"
                     /translation="MQEKKTALIAGASGIVGRGIAERLVGDGWRVLCASRSGGGHLPG
                     TEGVAVDLLDAEACARAVAPHAGITHVFHAAFQPAPSRAAEVAPNLAMLRNVVEAVQQ
                     ASPALRKVVLVTGAKFYGIQWGASSTPCRESDPRQLPPNFYYDQEDWLREASRSARWR
                     WVNLIPPFVSGYAVGNPMNLVLGIGLYAAVCKELGMPLRFPGSVGAYEALHQIADARQ
                     IGAAAAWAADAPAAEDEAFNVTNGDPARWRHTWPVLAEALGMAFAEPKTLPLADLMPA
                     QQAVWDRIARRHGLRTIDIGKIVEWRWIDYMLRQSHDIVLATAKIRRAGFNDCIETDA
                     TLVQRLRELQASEVLPA"
     gene            complement(13288..13908)
                     /locus_tag="P5537_12055"
                     /pseudo
     CDS             complement(13288..13908)
                     /locus_tag="P5537_12055"
                     /inference="COORDINATES: protein motif:HMM:NF015366.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter substrate
                     binding protein"
BASE COUNT         2404 a         4766 c         4459 g         2245 t
ORIGIN      
        1 ccagtgctag cttttcgtac cgtcacttat tgcactgaaa acgaggagac cccggtacac
       61 ctcagacaac gcgtccacca tcatcagcac cagcgggttg tgcgtcgctt gcgcgatgag
      121 ccggtagaac tcgatcaccg actgcgtgtt gcgcgaggcg cgccccagtc ggaacagatc
      181 cgcatgcagg tcgatgtcgc gctggatcgt gtcgaactcc tcgttggtcg cgcgcgggca
      241 ggcgaggcgg atcgccacgc agatgatctc ggtgcgcgcc tccatcacgt tctccagcga
      301 cgcctgcgcg agcgacacca tgtcctgcac cgtctgcgca agaccgccgc tgccgccatt
      361 cctgatgaag aagccgccct ggatgccctt gcgcgcttcc accacgcccg agacctccag
      421 gctgcgcaat gcgtcgcgtg ctgccgcgcg tccgatgccg aagcgctcgg ccagttcgcg
      481 ctcgccgggg agctggtcgc ccggcttcag ctcgccgctc atcaactgtt cgcgaatgcg
      541 gtcgcacacg gcctcgaagc cacgccgggt gcgcacaggt tggaagagcg attcgttggt
      601 catgaaagat ccttttgagg gttcggcagt attgcatatt cattggttga actataagat
      661 gattcgccat ggacttggac ctcacccccg aacagcgcgc cttccgtgac gaggtgcgca
      721 ccttcatccg cgaaaagctg ccctcagaga tccgcgaacg cctgcgtgcc ggccatccgc
      781 cgcgcaagca ggacacagtg gcctggcagc gcatcctcaa cgagcgtggc tgggccgcgc
      841 cgcactggcc caagcgctac ggcggcgccg acctcggccc gatggaacgc ctgatcctgc
      901 tcgacgaaac ctatcgcgcc cccgccccgc tgccgcaggt gctcaacgtc ggcatgctcg
      961 gcccggtgct gatgaagttc ggcacgcctg cacagtgcga ccacttcctg ccgcgcctcg
     1021 cgaatctcga tatctggttc tgccagggct tctcggagcc cggctccggc tccgacctcg
     1081 cgtcgcttcg cactgccgca cgccgcgagg gcgatcacta catcgtcaac ggccagaaga
     1141 tctggaccac cactgcgcac ctcgccgact gggtgttcgc cctcgtgcgc accgataccg
     1201 aggcgcgcaa gcaggaaggc atttctttcc tgctgatcga cctgcgcacc cccggcatca
     1261 cgatccggcc gatccactcc atcgacggcg agcaccatct caacgaagtc ttcttcgacg
     1321 aggtgcgcgt gcccgttggc aacctggtcg gccaggagaa caagggctgg gattgcgcga
     1381 agttcctgct gtcgaacgaa cgcacgggca tcgccaacgt cggcctgtgc cgcgagcggc
     1441 tcgactacgc gcgcgaactc gccggacgct acacacaggc cggcaagccg ctgctcgacg
     1501 accccaagct gcgcgcagac atcgccatgc tggaggccga gacgcgcgcg ctggagatca
     1561 ccaactggcg cttcctgctc accgacagcg agcagaagcg cctgccggcc ttcgcgtcgg
     1621 tactcaagct caagggcacc gagttgcagc aggagatcaa cgcgcttctc gcacgcatcg
     1681 tcggcccggg cggtctggag cgccgctccg ccgacgaagt cacgcacggt ccgattgtgc
     1741 cgcgctattt ctattcgcgc gcagcgtcga tctacggcgg cacgaccgaa gtgcagaagg
     1801 acatcctggc caaggccatc gtcggataag gcaaacatga atttcgaact gaatgaggat
     1861 caggcggcgc tcgcggagag cctttcccgc ctgctggccg atcgctatgg attcgagaag
     1921 cgccgtgcgc tcaccgcctc cggcgcagcg catgacgaaa agacctgggc tggattggcc
     1981 gagctgggcc tgacagcgtt gccagtgcca gaagcactcg gcggcttcgg tggcggtgcg
     2041 cgcgacctgc tgcccgcgat gcaggccttc ggccgctcgc tctcgatgga gccgttcctg
     2101 gcgagcgcgg tgctcgcagg caccgccctg cgcctcggcg ccgacgaggc gatgcagaca
     2161 cgactgctgc ccggcatggc cagcggcgag atcgtgtcgg cctgggcgca tgacgaaccc
     2221 gccggccgtc acgcgccgct gtgggtggag acgcgtgccg aacgcaagga cggcggctgg
     2281 aagctcgacg gcatcaagtc caacgtgccc gccggaggtc tggcgcggta cttcgtcgtg
     2341 agcgcgcgca tcgccggtgc accggctgac gcgaacgggt gcgcgctgtt cctcgtggac
     2401 gccaaggacg caggcgtcgc gctgcgcgag ttccgcctgg tcgatgacac agcagcaggc
     2461 gagctggtgc tgacgcaagc agcggcgcag ccgttggcca accccgaaga ttcgactcgc
     2521 acgcgtctcg ccatccaagg caccgtggcc gctggcatcg ccgccgtgtg cgccgacatg
     2581 agcggcgccg cccaggccgc cttcgatctc gcgatggact acctgcgcac acgcaagcag
     2641 ttcggccgcc tgatcggcga gaaccaggcg ctgcgccatc gcgcgtccga gatgctggtc
     2701 agcctcgaga tggcgcgcag catggccatg gccgccgctg ttgcggcaga cgatgccagc
     2761 gcggaagaca gtgcccccga cctgcatcgc gcgaagctct ccgtcgcccg caacgcacgc
     2821 aacgtggcgc tcggcgcgat ccagcttcac ggcggcatcg gcatgacaga ggaatacgcc
     2881 gtcgggcact acctgcggcg catccacgtg ctcgaccaga tgttcggcga cgccgacgcc
     2941 catgccgcgc gtctcgcggc tgcccttctt tgagacctac accgatgagc atcaccccca
     3001 tgatctacct cgacggccgc ggcgtgacgc gcgacgaggt gctgcgcgtg gcgcagcagg
     3061 cagccacggg cttcgagcaa ctcggcgtga gcgaaggcga caccgtcgcc ctgctgctgc
     3121 gcaacgactt cgccttcttc gaagtacagc aggccgccgc cgcggtcggc gcctatggcg
     3181 tgccgctcaa ctggcacggc cgcacggaag aagtgatcta cgtgctcgaa gacgcgaagc
     3241 cgaaggtgct ggtcgcgcat gccgaccttc tcgccccgat ccgcgcgctc gtgcccgcgg
     3301 gcatccgcgt cttcgtggtg ccgacgccgc cggaaatcca gcagcgctac ggcgtctcga
     3361 ccgaactcgc acggccctta ccgggcgaca cggtttggcg cgaatgggcc gagcgcttcg
     3421 agccgctgca ggcgccgccg cgccgcgccc gcgcgaccat gatctacacc tccggcacca
     3481 ccggccatcc caagggcgtg aagcgccagc ccgccacgcc cgaggaaagc aaggcctatg
     3541 tcgagttgtt cgccagcgtg tatgggctca agcccggcat gcgtgcgctg gtgtgcggcc
     3601 cgctctacca cgcgtcgccc aacgggtacg gccgtcaggc gctgatgacg gcggacgtgc
     3661 tggtgctgca gtccaagttc gatccggaag agacgctggc gctgatcgag aagcaccgca
     3721 tcgacaacgc ggtgatggtg cccacgatgt tcgtgcgcat gctcaagctg ccgccggagg
     3781 tgcgcaaccg ctacgacgtg cgctcgctgc gatgggtgac gcacaccggc gcgccgtgtc
     3841 cgcgcgaggt gaagaaggat ctgatggatt ggtggggtcc cgtggtctac gagggctacg
     3901 gcggcactga agtcggtacc gtcacgctcg ccacgccgca ggactggctg gagcatcccg
     3961 gttgcgtcgg catgcccacg cccggcacgc gcatggcctt ctatgacgag gagggaaatc
     4021 gcctgcccga aggcgagatc ggcgagatct ttgctcgcgt gccagcgtat cccgacttca
     4081 cttatctcaa ccacgaagag aagcgaaaga gcgtggagcg cgacggcctc atcagcctgg
     4141 gcgacgtggg ctacatgaag gaaggccggc tctatctctg tgaccgccgt tcggacatgg
     4201 tgatcttcgg cggcaccaac atctatccgg ccgagataga gatggtgctg acccagtgcc
     4261 ctggcgtgaa ggactgcgcc gtgttcggca ttcccgacga cgacttcggc gaatcgctcg
     4321 ctgccgctgt cgaacgcatg cccgagtcgc aagtcacgcc ggaggagatc cggtcctatc
     4381 ttctcgaacg tctcgcgaag ttcaaggtgc ccaagcggat cgacttccac gaatcgctgc
     4441 cgcgcgagga cagcggcaag atcttcaagc gccgcttgcg cgacccgttc tggcagaacg
     4501 ccgggcgcaa gatttgaggg gcggcgcatg ggcaagtggc tgcaatccaa tgaacacctc
     4561 accttcgagg tgcgagagcg cgtcgcgcgc atcaccctca accggccgga ccggcgcaat
     4621 gcgctgtcgt gggagatgct ctccgagctg cgcgcagcgc tgctggaggc cgacgacctg
     4681 cggagcgtga gcgtgatcgt gctcggaggc gcaggccccg atttctgcgc gggctacgac
     4741 atgaagtcgg cctacgcgcg ctacgccgcc gaaggcgatg ccgcgctcgc accctcagcg
     4801 cgccatcgaa ggcaccgatc tcgcggcgga tcaacgcatc gagcgcgctc gtctgcgccg
     4861 cgtcgagcgc acttgctgtc gtgaatgttg cggcggatga atttttcagt ttgtcgtata
     4921 atctatggtt gaaccaatga tttcgacgaa tcgtatggca gccagatcca tcacacaagg
     4981 agacatcgca atgaagttca ctcgacgcca gacgcttgct gcagccctgg gctcgctcgg
     5041 tgcgggcgtt ctgccgcgcg cgcaggcgca gacgcagccc ttcccttcac aggtcatcaa
     5101 gttcgtgatt cctacgccgg cgggcgggga ccacgacacc atgatgcgga tcattggcca
     5161 gaagctgacc gacgcctggg gccagccctg catcgtcgaa tccaggtccg gtgcgagcgg
     5221 cgccatcgcc gcagccacgg tgtcgcaggc gccggcggac ggatacaccg tgctgctcgg
     5281 ctacagcgcg cttctcagca acacggtgct gatgccgaag ccgggctatc ggctcgaaga
     5341 cctgcagccg gtcggaatgc tggctctcac gccgatcgcg ttcggcgttc gcgagagcct
     5401 gccggcctcg acgctcaagc aatacgtggc gctcgccaag acacggcccg gcaagctctc
     5461 ctatggctcc tatggtccag gctcgggtgg tcacttcgtc ggcgagctgt tcaacatggc
     5521 agccggcatc gacaccgtgc acgtgccgta caagggccag ccgcccgcgt tgcaggacct
     5581 cattggcgga cggatcgacg cggcagtggc gtcgctcggc cgcgtgaacc gctaccccgg
     5641 caagatcaag cctcttgccg ttgccagcgc cacgcgcttt ccttcgtatc ccgacgtgcc
     5701 gaccttcgcc gannnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnaggtcctt
     5821 ccaggtaagc atgcatcgag ccccagcgct tgtcgatttc atcgaatgcg cattgcagat
     5881 agtcggcgtg caccgtggct cgcagtgccc agtcggcgga aacaccctgc atggaccagc
     5941 gaccgttgct cgccataaag tcgtcgagca cagtttcgcg cggcacgccg agcgcaagca
     6001 gcagcaacgc caaagcccag ccggtgcgat cctttccggc ggtgcagtga accaccaacg
     6061 ggagcggcgt cgcctcatcg gcgaccagcc gcaggagcga ggcgaagaca ggcgtgtgtt
     6121 cgttcacgaa gcgccgatag acttcgaaca tgatggcggc cagcgcggac ttgtcgggtc
     6181 cacccgcctc acgcagttcg cgcagcgcgc ccatcgcgcg cggctcgatc ggcagatgcg
     6241 gctcgcggat gccgaattgc gccaggcgcg acggcgcacg ggtccgcgcg tccgcgtccc
     6301 gcagatcgat caccgactac agtccaatgg cgcgcagcgc atccagttcg tcgtccgaga
     6361 ccgaaccgaa gtgactggaa cgccagagtc gaccgggtgc aatgacatgg cccgacgcgg
     6421 tggcgatgcc acccaggtcg cgcaggttcg gcacgccggc ggcgaccagc ccagtcatcg
     6481 agcccccagg acagcgcgtc cgttggccag cacctggacg ccgcgctcct tcacgctggc
     6541 acggaaggcg atctcctccg agcccagtcg ccagcaatca agcaccagcg tttctccggg
     6601 atagaccggc gaagtcaacc gcgcgcggat cgacttcatg cgcgacgcat cgtgcccgca
     6661 gaacttcgcc aggatgccgc ggcatgcgtt gccataggtt gcgaggccat gcaggatcgg
     6721 tcggggaaat ccggccttgg cagcaactgc aggatcgatg tgcagcggat tgatgtcgcc
     6781 cgagagacgg tacagcacgg cggcatccgc gcgggtcggc atttcgatcg tcacctccgg
     6841 cgccgcatcg ggtgtcgcag gcgcagcagg cacaggctcg tccccaccgc cgttcttcga
     6901 gaacccacca tcgccgcgca agaaggccac catctccgcg gtggcgaccg gccgtccgct
     6961 cgcttcgtcg gtgagggtct tctccacatg catcgtcgcg cccttgccct cgcccttgtc
     7021 gacgatgcgg gtgacgcggc tctggccgat cagcgtgccg gctgcgggca acggcgaatg
     7081 gatcgtcacg ccctgttcgc cgtgcacgag cttcaggtag tcgatgccga gttccttgcg
     7141 atcacgcatc cagaagccag gcgatgccag gaccgctgcc atcgtcggta cggcctggag
     7201 ttccttttcg tagacgaagc gcagctcttc caacaccagc ggatcggcgg cgaaaccgac
     7261 gccgagggca tagaggatgg tgtcgcgctc ggtataggtg tggcgcaccg gatcggaacg
     7321 ccaggccttc gtcttctcgt agtcgatcat gctttcaatc cttgttcggc cagcagaact
     7381 gcgccggctc cttggcagcg aagcggcgga tcgcttcgcg gaagtacgca ctggacaagg
     7441 caatcgcctg cgatgacgct tccatgtcca gcatcgtctc cagatcgctc tgcaaggtcg
     7501 cggccagcgc gcgcttggag aggctgaatg ccgtcggcga tgcacccgcg agactgcggg
     7561 ccagttccat tgcgcgcggc atcagggcct ccggcgcgag agcctccagc gcgatgttca
     7621 tgcgcaccgc ctcgtcggca ccgaactcgc gggccgaata gatcagttcc ttggcacgct
     7681 gcaaccccac cacacgtggc aactggtacc aggcacctac atcgggcacg aggccgatgc
     7741 gatggaacac catggctagg cgcgcgcgcg tgctcaccag aacgatgtcg gcatagagcg
     7801 ccatgctgag gcccgcgcca aaagcgacgc cgtcgactgc ggcgatcaac ggcttgtcca
     7861 gcgacgccag cgcgcgagcc agttcggcat agcgcgccat gcccgcgcgg cgctgctcga
     7921 ccgtccgcga ggcgccatcg gccatgccct tgacgtcgcc gcccgcgcag aagtcgccgc
     7981 ccgcacccgc caacaccacg gcgcggatgt cgtcggcggc acgcagccca cgcaaggctg
     8041 cgacgagcgc gtcggtggtc gggatatcga tcgcgttctt tgccgatggc cggttcagcg
     8101 tgaggacggc cacgccgtcc gcgcgctcga agaggacgct gtcgcccgtc atgtcagagg
     8161 ctgatgtgga tgccgccgtt cacacccaga tgctggcccg tgatgtaact cgatccatcc
     8221 gacagaagga agcagacgct cttcaccacc tcgcccggcg tggaccagcg acccaacgga
     8281 atctgagcga gcatcccgtc gcggaacttc tcgccgcgca cgacttcggt catcggcgtt
     8341 tcgaccacgc cgaagcagat cgagttggtg cggatgttgt agcgacccca ttcgcgtgcg
     8401 gcggtcatcg tcatgcccag catgccggcc ttggctgctg cgtagttgat ctggccgatc
     8461 gagcccctgc gcccggcttc ggacgagatg ttgacgatcg agccgcccgt cctttcgccg
     8521 cccttggacc gctcgaccat gtgacggccg gtggcacgca tccagtagaa agaaccggtg
     8581 aggtgcacgt cgatcacctc ctgccattgc tggtcggtca tcttgtcgat cattgcgggg
     8641 cggatgatgc cggcgttgtt cacgaggccg tgcacagcgc cgaacttggc aaccgcttcg
     8701 gtaaccgcac gatcggccac agccgggtcg gccacgctgc cttgcactgc aagcacgcgc
     8761 gcctgcggca gcggggagac cgcggcgtcg agcgtctgac cgttgaggtc gacggccacc
     8821 acgttggcgc cgagttcgat ggccagttcc acaatgccct tgccgatgcc ttggccggcc
     8881 ccggtgacga cgatggtgcg cccttgcagg ctgacgatgg gatccacttt gatgctcctt
     8941 gtttgcttgt tcgatggttg aaccaatgat atcctactcg cgaacagtgg ctggagcaaa
     9001 cacatgacca tcaaacgcaa ggcctgcatc gcaggcgcct atgaacaccc gacccgcaag
     9061 gcccccgaca agacagtggc gcaactgcac gctgaatgcg cgcgcggcgc gctggcggat
     9121 gccggactca ccctacagga cgtcgacggc tacttctgcg ctggcgatgc gcccggcctg
     9181 ggtgccaaca acatggccga ctatctgggc ctgaccaagc tgcgccatat agacaccacc
     9241 gacaccggcg gttcggccta cctgatccac gtgtcgcacg cggcgcaggc gatcgccgcc
     9301 ggcaagtgcg atgtcgcgct ggtgaccctc gcgggtcgtc cgcgcagcga aggatcgagc
     9361 ggcgtcgcgc cccggctcgt cacggccaac acgccggacg tgccctggga gatgccctac
     9421 agccccgtca tcgtgaacat gtacgcgctg gctgccgcgc gccacatgca cgagtacggc
     9481 accaccagcg agcaactcgc gtggatcaag gtggcagccg ctgcgcatgc gcagcacaac
     9541 ccgaacgcga tgctgcgcga accggtgacg gtggaagaag tgctggcctc cccgatgatt
     9601 tccgatccac tgcacaagct ggactgctgc gtggtgagcg acggcggcgg cgcgctggtg
     9661 gtggtgcggc ccgagatcgc cgcgcgcctg aagcgcccgg tggtcaacat cctcggcgcg
     9721 ggcgaaacca tcaagggtca gctcggcggc cacgtcgacc tgacctggtc cggcgcagcg
     9781 atctccgggc cgatcgcgtt caaggaagcg ggcgtgagcc cggccgacat ccagtacgca
     9841 tcgatctacg acagcttcac catcaccgtg ctgatgcagc tggaagacct cggcttctgc
     9901 aagaagggtg aaggcggtcg cttcgtggcc gacggcaacc tgatctcggg cgtcggcacg
     9961 ctgcctttca ataccgacgg tggcgggctg tgcaacaacc atccggccaa tcgcggcggc
    10021 atcacgaagg tgatcgaggc cgtgcgccag ttgcgcggcg aagcacaccc gaaggtccag
    10081 gtgcccgact gcaccctggc tctcgcccaa ggcaccggcg gcctgctcgg ctcgcgccac
    10141 ggcagcgcca ccctgatcat ggaaaggcaa taagcgatga ccactcccta caccgagcgc
    10201 ccactggcac ccgtgaccgt cgacgccgcc accgagcact tctggacgca ggccaaggaa
    10261 ggccttcttt gcacgcggcg ctgcaccagt tgcggcgagg tccactggta tccgcgcgcg
    10321 ctctgcccct tctgcatggg cgacaccgag tggtgcagcc tctcgggact gggcacgatc
    10381 tacagcgtga gcgtgacgcg acgcgccggg cccattgcct acgcgatcgc ctacgtcgcg
    10441 ctcgatgaag gcatcaccct gctcaccaac atcgtcgact gcgatttcga tgacctgaag
    10501 atcgggcaac gcgtcgaggt gaccttcaag ccggcagagg gcggcgcgat ggtcccgatg
    10561 ttcaagccgg cctgagccca gtgcagatgg agacgctcga tttctctgtg gagaacgcgg
    10621 tcggctggat tcgcctcacc cggccggaga tccacaaccc gctggacgtg ccgctgcgca
    10681 ccgacctcat gacggtgctg gagcaagtgc gcaacgaccc tgcggtgcgc gtactcgtcc
    10741 tcaacggcgg cgcgggcgcc ttctgcgccg ggggcaacct ccacgcgctg caggagcatg
    10801 cgaatgcagg gcccgcctac tggcaacggc ggatcaacgc cggtcttcgc ctcaccgacg
    10861 atctgctgaa cgtgggctgc cccgtgatcg ccgccatcga cggtccggcg atcggcgccg
    10921 gtttcgcgct ggcgctctcc gcggacatga tcatcgccag cccgcgcgcg aaattcgcca
    10981 tggcccactt gcggctcgga ctcgtgccgg accttggcgc gctctatctg ctgccgcgtg
    11041 ttgtggggct ccagcgtgcg aaggagctgg tgttctccac gcgcgatgtc agcgccgacg
    11101 aggctcgcga actcggcatc gtgatggagg tgcacgccag cgaagcgctc gaagcacgtg
    11161 cgcgcgacat ggccgaacgc atggcccggg ccgcgccgac cgcagtcgcg ctttccaagg
    11221 caatgttgaa tgcctcgctc gatagcgaca gacagagcgc cttcgcgctg gaagccgcca
    11281 gccaggctgc cgctttcgcg gcgccggaac cggccgcgca ggttgaagca attcttggaa
    11341 aacagcgtcc ggccttcagc ggcctgaagt acgcgcgagg ctgacgacct cagccgaagt
    11401 gcgatacgaa gaaggccatg gccttctccg ctgcacgtcg cgcgcgttcg cctcctggca
    11461 gcgtggcgtc ggcaatgacg ggcgtttcca actcgatctc cgcgtccggc gacaaggctt
    11521 ccacaagccc tttcagatcg agccccccat cgcccacgta catgcggccc gacatcgctt
    11581 cgtcgaacag ggtcgtttcg gccgcccgca cggcgggcgc atcacagagt tgcgtgagat
    11641 ggatgcatcg ggcgtcgagc gcacgcacgt ccgcgccgcc ggcgcccgag cgcgcgagat
    11701 ggagcgagtc gatcagcagg cccacgttgc gcgcaccgct gtcggcaatc acgcgctgcg
    11761 catcggcaat cgtcttgagc gagctcatgg gcatgaactc gagcgcaatg cgcacgccgg
    11821 catcgtcggc cgcgcgcgcg tagtcgcgca gcagttcggc cacgcgcgac ggatcaggct
    11881 cgaagcatcc ctgcgagatc agcggcgcac cgacgcggcg tgcggcttcg acgttggcga
    11941 gcaggtgcga caggctcgtc ttctccgaca tgtagtagcc ggagatgctt gagatgcgga
    12001 tcgagagcgc ctcggctcgc gcgcgtatcc gttccaggcc gtcaccctcg gcattcggct
    12061 gcggccacgg atcaccggga ttgcgaccgc tgacacgcaa gcccacagcg ccgaagcctg
    12121 cttcggctgc tgccgagagc acatccagcg gcgctgcatt ggcaccgaga gaaagaaagc
    12181 ccagcgtgag cgcgcggact tcgcggcgac gtggattgcc gctcatgccg gcaacacctc
    12241 gctggcctgc agttcgcgca ggcgctgcac cagcgtcgca tcggtctcga tgcagtcgtt
    12301 gaaaccggcg cgccggatct tcgccgtcgc cagcacgatg tcatgcgact ggcgcagcat
    12361 gtagtcgatc catcgccatt cgacgatctt gccgatgtcg atcgtccgca gtccatgccg
    12421 gcgcgcgatg cgatcccaca ccgcttgctg cgccggcatc aggtccgcga gaggcagcgt
    12481 cttcggctcg gcgaaggcca tgccgagcgc ttccgcgagc acaggccacg tatgacgcca
    12541 gcgcgccgga tcgccgttgg tgacgttgaa ggcctcatcc tcggctgctg gcgcatccgc
    12601 cgcccacgcc gctgcggcgc cgatctgccg cgcgtccgcg atctggtgca gggcctcgta
    12661 ggcgcccaca ctgccgggaa agcgcagtgg catgccaagc tccttgcaca ccgcggcata
    12721 gagcccgatg cccagcacca ggttcatcgg attgcccact gcatagccgg aaacgaaagg
    12781 cggaatcaga ttgacccaac gccagcgcgc gctgcgactc gcttcgcgca accagtcctc
    12841 ctggtcgtag tagaagttcg gcggcagttg tctcgggtcg ctctcgcggc aaggcgtcga
    12901 gctcgcgccc cactggatgc cgtagaactt cgcgcccgtg accagcacca ccttgcgcaa
    12961 tgccggcgag gcctgctgca ccgcctcgac cacattgcgc agcatcgcca ggttgggtgc
    13021 cacttcggcc gcgcggctgg gtgccggctg aaaggccgca tggaagacat gcgtgatgcc
    13081 cgcgtgcggc gccacagccc ttgcgcaagc ctcggcatcc aggaggtcca ccgccacacc
    13141 ttccgtaccc ggcaagtggc cgccaccgga gcggctcgcg cacagcacgc gccagccatc
    13201 accgaccagg cgctcggcaa tgccgcgccc cacgatgccg ctcgcgccag cgatcagcgc
    13261 cgtcttcttc tcttgcatgc gggcgcctca actgctgagc gtgatgccga gtcgcttgat
    13321 gagatcgccc catgtctggc tgtcgctcag cgccaggttg cggaaggcct cgccatgcac
    13381 cagcgaaggc acgccgccgg tgcggcgcac ggactcctgg aacgcgggat cggcctgcat
    13441 gtccgcgacg gccttcagaa gcttcgacgt caccggagcc ggcatgttgg ccggcccgac
    13501 catgccgaag agttggtccg gaatccgcac cggcaggccg gattcactca gattgggcac
    13561 gttcggcaaa gcgggatcac ggccctcgcc cgtcaccgcc agcgccttga tgcgcccggc
    13621 ctggatgagc ggcagcgaag tggccagcga cgcaatcgtg tactgcactt cgccggcaat
    13681 catggccgta tcggtctcgt tgcccgtctt gaaaggcacg tgcaccgcct tgatgccgac
    13741 ggccgcgttg aactgctcga ccgccaggtg aatgctgttg cccaccccgc tcgatccgaa
    13801 gttgagcgtg ccgggcttgg ccttggccag tgcgatgaaa tcctgcagcg tgtccacgcc
    13861 gagcttgggc gacaccgtca ggacctggcg cgatgtctgg atcaggccaa ggtaggtgaa
    13921 ggggtctcct cgttttcagt gcaataagtg acggtacgca aagctagcac tggc
//
LOCUS       DAOTIN010000084        13703 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_5362_length_13703_cov_8.434130, whole genome shotgun sequence.
ACCESSION   DAOTIN010000084 DAOTIN010000000
VERSION     DAOTIN010000084.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 13703)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 13703)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13703
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5362_length_13703_cov_8.434130"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..2187
                     /locus_tag="P5537_12060"
     CDS             <1..2187
                     /locus_tag="P5537_12060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proton-conducting transporter membrane subunit"
                     /protein_id="HRV78817.1"
                     /translation="FHFWLPHAMAAPTPVSAYLHSATMVKAGLFLMARMWPVLAGTPE
                     WFYLVATTGLVTMLVAAGIALFKDDLKGLLAYSTVSHLGLVTMLLGFGTPLAAVAAVF
                     HILNHATFKAALFMNAGIVDHEAGTRDIRRLGGLLQLMPITATLAMVAGASMAGLPPL
                     NGFISKEMMLHEAVDTAWLGNGWIVAALATLAACFSVAYSFRYIVHVFFGARRDDYPH
                     APHDPPAGMWLPPALLVVLVVAIGLFPDTVAGPLVAVVARAVTGGAVMDYHLALWHGF
                     TPALGLSAIAVTVGLGALLAYRRVRALWQAGPHPEAKAMFDAFIEGAAALARGVTHGL
                     HNGSLQRYLAFALGAFTLAGFAAFLAAPHEAGTRALLPAHPAAIAAWLLLVGGCALTV
                     MLFRRRVLSVLVVGTVGLIVCVAFIYLSAPDLALTQISVEVGTVILILLALYFLPKEG
                     PQSSSVRADPLRHLRDGVLAVVAGVGMAGASWAMLTRDGTSLSHYYLENSVSGGGGTN
                     VVNVILVDFRGFDTFGEITVLGIAALAIYALLDGALFGRTGRRLGAWSPDRPQSADRH
                     PMIMVVATRVMLPLAMLVGAYIFLRGHNQPGGGFIAALVVSIALIMQYMASGFGWAAQ
                     RVKVNYHAMIGLGVLVAAATGIGAMVLDQPFLTSTFGHFHLPLVGEFELASAMAFDTG
                     VFLTVVGAVMLMLANLSRMGRWTSPYTINTGAMDVDPRATSGKEQG"
     gene            2187..2597
                     /locus_tag="P5537_12065"
     CDS             2187..2597
                     /locus_tag="P5537_12065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter subunit C"
                     /protein_id="HRV78818.1"
                     /translation="MEFLVASAIGVMTAAGIYMVLRARTFPVVIGLSLLTYATNLFLF
                     ATGRLAIGRPPVISADAAGYIDPLPQALVLTAIVISFGMTAVVVVMALRAYLETGNDH
                     VDLPGDASPEATEDDWKLRGRKPAPAPGGRGGRA"
     gene            2594..4117
                     /locus_tag="P5537_12070"
     CDS             2594..4117
                     /locus_tag="P5537_12070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monovalent cation/H+ antiporter subunit D"
                     /protein_id="HRV78819.1"
                     /translation="MNHLLILPILLPAVVGALLVLAARHDSVLARSFAVASTVLMLGI
                     AVALLVLASDGQVRSYALGAWPAPFGIVLALDRLSALMLVLTAVLGLGVLLYAIGGWD
                     QRGKHFHPLFQFELMGINGAFLTGDFFNLFVFFEILLIASYGLMVHGGGGLRVKAGVQ
                     YVVTNLVGSSVFLIAVGMIYSVTGTLNMADLARIVPQVAAADQALLQTGAVLLLLVFA
                     VKAALVPLHFWLPGTYANAPGPVAALFAIMTKVGAYSIIRLYVLAFGADAGAAAWLAA
                     PWLLPAGLVTLVLGMTGVLAARSLGQMASFAVIGSMGMLLATVAVFTPQATSAALYYL
                     IHSTLAAGALFLVADLVAERRGAQRDRFAAAPRIAQGGLVGGLFFVAAIAMTGMPPLS
                     GFIGKLLVLDGVRASAHASWFWALILSTSLIAIVGFSRAGSFVFWKAHALPAAPAPGY
                     RPDGALSFVAVGGLLACLVLLTAFAGPVHAWLELVAAQLYAPAGYIDAVLGTAQGVR"
     gene            4117..4644
                     /locus_tag="P5537_12075"
     CDS             4117..4644
                     /locus_tag="P5537_12075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter subunit E"
                     /protein_id="HRV78820.1"
                     /translation="MGARHDRLDERTFMERWLPHPLMTAVLVLLWMLLLNSFSFGGLL
                     VGVVLAVVITRVTSNFWPERPPVKSWSKAFAYLGVVAWDVVVANLQVTRLILFRPVES
                     LATRWVVLSLELRSPEAITVLAGTITMTPGTVSCDLSADGRSLLVHCLDAPDAEDTVR
                     QMKERYEDRLKEIFP"
     gene            4641..4910
                     /locus_tag="P5537_12080"
     CDS             4641..4910
                     /locus_tag="P5537_12080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015075 - monoatomic ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="K+/H+ antiporter subunit F"
                     /protein_id="HRV78821.1"
                     /translation="MIEYALQFGFAAASLALLLNLWRLLRGPALMDRVLAVDTMVINI
                     IALIVLAGIHERSTIFFEAALLFAMFGFISTVAYCRFILRGDVIE"
     gene            4924..5331
                     /locus_tag="P5537_12085"
     CDS             4924..5331
                     /locus_tag="P5537_12085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051139 - metal cation:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0098662 - inorganic cation transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter subunit G"
                     /protein_id="HRV78822.1"
                     /translation="MTFVLELLVSLLIVGGGAFLLIGSIGMVKLPDLLTRLHAPTKAT
                     TLGVGGALVASMVFFAGLEGTLSIHEVLITAFLFMTAPISAHFIAKAHLHEHTELRDG
                     LPPTGRPVGWSTFDAAPGAGEADEDDGRRGAHD"
     gene            5379..6719
                     /locus_tag="P5537_12090"
     CDS             5379..6719
                     /locus_tag="P5537_12090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011764562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HRV78823.1"
                     /translation="MNTIRRKPPTPQPSRIQGTLGVRKSADEEPSAEEAPSARDPAAD
                     ARTPRGEAPARPAGGEGPGRRPGRATKPERNERAPRRDDGARPGRREEDAKPARGERA
                     ARSAGTSARDDERPARGEWGRKRADDERAPRRESAPARRDDGRAAPRASGPKRRDEER
                     SQRRDAAPQRRGEQAPPAAAAASYEARAASAAAIAEAAQARAAVEGVRLSKLMAERGL
                     CSRREADEFIERGWVFVDGRRVSELGVRVGQDARITLAPEAARTQQQRATILLHKPVG
                     YVSGQPEPGYAPAVSLIGPDNQADRDTAQRFHPSHLKNLAPAGRLDIDSTGLLVLTQD
                     GRVARQLIGEDSKVEKEYIVRVEGTLAENGLALLNHGLWLDDRPLRPAEVEWINDEQL
                     RFVLREGRKRQIRRMCELVGLKVVGLKRVRIGRVKLGDLPLGQWRFLREDERFG"
     gene            complement(6865..7254)
                     /gene="mnhG"
                     /locus_tag="P5537_12095"
     CDS             complement(6865..7254)
                     /gene="mnhG"
                     /locus_tag="P5537_12095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051139 - metal cation:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0098662 - inorganic cation transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="monovalent cation/H(+) antiporter subunit G"
                     /protein_id="HRV78824.1"
                     /translation="MSGLLAWLSAALLLLGASIGLIGAIGVLRLPDSYTRLHAASKAG
                     ALGAALILAGVAAASEGGFALAALFAMLVLLATAPLAAHAMARAAHRSGIAPLTGALG
                     DALAEAEALAEADPETSPPKHGARVGR"
     gene            complement(7251..7712)
                     /locus_tag="P5537_12100"
     CDS             complement(7251..7712)
                     /locus_tag="P5537_12100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015075 - monoatomic ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="monovalent cation/H+ antiporter complex subunit
                     F"
                     /protein_id="HRV78825.1"
                     /translation="MNAAIAGAAWVLPLTFALLALGAALILLRLVRGPRAPDRVVAID
                     ALSMIAIAAIALLALATAQPMLLDAAVVLSLVSFLGTTAFILLFRRRGRGADEAATGA
                     DARLLAAGAAPGSTSAQAPGTEPEARETRTGGGAAPARRIREARANGEAAQ"
     gene            complement(7709..8221)
                     /locus_tag="P5537_12105"
     CDS             complement(7709..8221)
                     /locus_tag="P5537_12105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter subunit E"
                     /protein_id="HRV78826.1"
                     /translation="MLGLHLLLAVGLAAYADALRPLGVFAAFVAVYLALRLAIDLLGI
                     RRYLRRLELGTAFALWFVGEIFRASVGVARIVLGREVAPQPAVVAMRLARRDERFATL
                     LGCLLTLTPGTMALDYRPESGLMYIHALDARTAAEVEAGVRAIERRLLRWLDAGAPDV
                     AADGTGRDTT"
     gene            complement(8224..9738)
                     /locus_tag="P5537_12110"
     CDS             complement(8224..9738)
                     /locus_tag="P5537_12110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proton-conducting transporter membrane subunit"
                     /protein_id="HRV78827.1"
                     /translation="MNTLIVSPLLIPLATLVATLLARRSPRAVTAISLAGALALTAAG
                     LALVGLAAQGQILASQAGGWAAPYGITLVVDRLSAAMVAITGIVGTATIVFAMARDED
                     PARCRDFHPLVHGLLVGVCGAFITGDVFNLYVWFEVLLVGSFALLVLGGGRRRLSGTV
                     VYVVLNLVATMMFLLAAGMLYGASGSLNMALLAQAFAAGEVPTTAHAAVVLMLTAFSI
                     KAALFPVFGWLPASYHVAWTPVSALFAGLLTKVGVYALIRLVTLFWPDAGVAHEVLLW
                     VACATMLIGVLGAAAQVEVRRILSFHIVSQVGYMILGLAIATPLALAGAVFYLIHHIV
                     VKANLFFIGGIAARLTGSERLAAMGGLYARAPWLALLFAIPALSLAGIPPLSGFWAKF
                     VLVKASLDASAWIAAAVALVTGIFTLLSMSKIWNEAFLKPHPGGAGGGSGGGGSPRSA
                     DGLQPALWAVGTLAAMTVAIGLAAGPVMDYAVAAAEQLAAPAAYIDAVVRAGGN"
     gene            complement(9735..10115)
                     /locus_tag="P5537_12115"
     CDS             complement(9735..10115)
                     /locus_tag="P5537_12115"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit K"
                     /protein_id="HRV78828.1"
                     /translation="MEILVSLTVGALVAIGIWMMLDRGLLRVVLGVVVLGNGVNLAVF
                     SAGRLDGRAAAFVTEAGTPALAANPLPQALVLTAIVIGFALFVFALAVLKRSWELHGR
                     IETDLVTAVAEEPAPDLPPQGDKA"
     gene            complement(10118..12862)
                     /locus_tag="P5537_12120"
     CDS             complement(10118..12862)
                     /locus_tag="P5537_12120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proton-conducting transporter membrane subunit"
                     /protein_id="HRV78829.1"
                     /translation="MLASIGLIALAMLAAVPLAARLGQRAGWLLALAPLAAFIHFLTQ
                     MPTVAGGGVITSTLAWVPALGVELAFRLDGLSLLFALLITGIGTLIVLYAGTYLSDHH
                     HLGRFHAYLLGFMAAMLGLVLADDLIAMFVFWELTSVTSFLLIAFQHDKAESRRAALQ
                     ALLITGGGGLALLAGLILLGNVGGSWQFSGLSGEAIAGHALYPAILVLVLIGAFTKSA
                     QLPFHLWLPNAMAAPTPVSAYLHSATMVKAGVYLLARLNPALGGSPSWSTILITIGAA
                     TALVGAVLAIRQTDLKRVLAYTTVTVLGQLTMLLGTDTHYGLQAFAIYLVAHALYKAA
                     LFMAVGSIDHATGTRQIALLGGLIRHMPLTGFAVALAAFSNAGLPPFFGFIAKEFKYA
                     GLIELGLAGWITTAVMILTNALLLTAAGLVFVRAFLGREGRYPHAPHEVGVPMWIGPM
                     LLAIGGFVFGAFNNLAEVWLIDAAVQAVSRATVPVSLYLWGGFTPALLASLLTVALGV
                     FFYLQRTRLRRRLSLWRVLWRVSGDRIWDRLLKRVFAFATRVADRFQHGSLRQHISAL
                     VLAIAGFALIGLFASTGDDFAWPQATSPVNLAALLGCVLAVAGAAAAATTPGRVALVA
                     TLGASGLGMAMFFLAARAPDVAITQLMVETLTVIFLALVLRRLPPTRLVGSRKPAAKR
                     FHAVVAVVIGAVVAAMMLMTVSQPLPGDIARWYLDNSLPGGQGANVVNVILVDFRALD
                     TLGEILVVGLAGLAAAGLLAGGRRADEAAPTAGATAGSADFGSVLLREGILPLSALLA
                     LVALMLLWRGHNLPGGGFIGGLVAACAAVLVALAFGTTRARALLRVPPLAMLAGGLGI
                     AAVAGLVGLFHGEPFLTGNWIFPAGLPLGTPLLFDVGVFLTVLGAVLHMLLGLLEREG
                     "
     gene            complement(13139..13354)
                     /locus_tag="P5537_12125"
     CDS             complement(13139..13354)
                     /locus_tag="P5537_12125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78830.1"
                     /translation="MCTFDAPIARCEAMNEMVLLDETRRECALEHGCPPGQKCPLNGC
                     FARQSGLYEAHPEIGAHGQPRVAHHAH"
BASE COUNT         1952 a         4946 c         4926 g         1879 t
ORIGIN      
        1 ttccacttct ggctgccgca cgcgatggcg gcgccgaccc cggtgtcggc ctacctgcac
       61 tcggcgacca tggtgaaggc agggctcttc ctgatggcgc ggatgtggcc ggtgctcgcc
      121 ggcacgcccg agtggttcta cctcgtcgcc accaccggcc tggtgaccat gctggtggcg
      181 gccgggatcg cgctcttcaa ggacgacctc aagggcctgc tggcgtactc caccgtgagc
      241 cacctcggcc tggtgaccat gctgctcggc ttcggcacgc cgctggcggc ggtggcggcg
      301 gtgttccaca tcctcaacca cgccaccttc aaggcggcgc tgttcatgaa cgccggcatc
      361 gtcgaccatg aggccggcac gcgcgatatc cggcgcctcg gcggcctgct gcagctgatg
      421 ccgatcaccg cgaccttggc gatggtggcg ggcgcgtcga tggccggcct gccaccgctc
      481 aacggcttca tctccaagga gatgatgctg cacgaggcgg tcgacaccgc ctggctgggc
      541 aacggctgga tcgtcgccgc gctggccacc ctggcggcgt gcttctcggt ggcctactcc
      601 ttccgctaca tcgtgcatgt gttcttcggc gcccgtcgcg acgactaccc gcacgcgccg
      661 cacgacccgc ccgccggcat gtggctgccg ccggcgctgc tggtggtgct ggtggtggcg
      721 atcgggctct tccccgacac cgtggccggg ccgctggtgg cggtggtggc gcgcgcggtg
      781 accggcgggg cggtgatgga ctaccacctc gcgctctggc acggcttcac cccggcgctc
      841 ggcctgtcgg cgatcgcggt gaccgtcggc ctcggcgcgc tgctcgccta ccggcgcgtg
      901 cgcgcgctct ggcaggcggg gccgcacccc gaagccaagg cgatgttcga cgccttcatc
      961 gaaggcgcgg ccgcgctcgc gcgcggtgtc acccacggcc tgcacaacgg ctcgctgcag
     1021 cgctatctcg ccttcgcgct cggcgcgttc acgctcgccg gcttcgccgc cttcctcgcc
     1081 gcgccgcacg aggcgggcac gcgcgcgctg ctgcccgcgc acccggccgc gatcgccgcc
     1141 tggttgttgc tggtcggcgg ctgcgcgctc accgtgatgc tcttccgtcg ccgcgtgctg
     1201 tcggtgctgg tggtcggcac ggtgggcctg atcgtgtgcg tggccttcat ctacctgtcc
     1261 gcgcccgacc tcgcgctgac gcagatctcg gtcgaggtcg gcacggtcat cctgatcctg
     1321 ctcgcgctct acttcctgcc caaggagggg ccgcagagct cctcggtgcg cgccgatccg
     1381 ctgcgccacc tgcgcgacgg cgtgctcgcg gtcgtggccg gcgtcggcat ggcgggggcg
     1441 agctgggcga tgctgacccg cgacggcacc tcgctgtcgc actactacct cgagaactcg
     1501 gtgtcgggcg ggggcggcac caacgtggtc aacgtgatcc tggtcgactt ccgcggcttc
     1561 gacaccttcg gcgagatcac cgtgctcggc atcgccgcgc tggcgatcta cgcgctgctc
     1621 gacggcgcgc tgttcggccg caccggccgc cgcctcggcg cgtggtcgcc cgaccgcccg
     1681 cagtcggccg atcgccaccc gatgatcatg gtcgtggcca cccgggtgat gctgccgctg
     1741 gcgatgctgg tgggcgccta catcttcctg cgcggccaca accagcccgg cggcggcttc
     1801 atcgccgcgc tcgtggtgtc gatcgcgctg atcatgcagt acatggcgag cggcttcggc
     1861 tgggccgcgc agcgggtgaa ggtcaactac cacgccatga tcggcctcgg cgtgctggtc
     1921 gcggccgcca ccggcatcgg cgcgatggtg ctcgaccagc ccttcctgac ctcgaccttc
     1981 ggccacttcc acctgccgct ggtgggcgag ttcgaactcg ccagcgcgat ggccttcgac
     2041 accggggtct tcctcaccgt ggtcggggcg gtgatgctga tgctcgccaa cctgtcgcgc
     2101 atggggcgct ggaccagccc ctacacgatc aacaccggcg cgatggatgt ggacccgcgc
     2161 gccacctcgg gcaaggagca gggctgatgg agttcctcgt cgccagcgcg atcggcgtga
     2221 tgaccgcggc cggcatctac atggtgctgc gcgcgcgcac cttcccggtg gtgatcggcc
     2281 tgtcgctgct cacctacgcc accaacctgt tcctgttcgc caccggccgc ctggcgatcg
     2341 gccggccgcc ggtgatctcc gccgacgcgg cgggctacat cgacccgctg ccgcaggccc
     2401 tggtgctcac cgcgatcgtg atctccttcg gcatgaccgc ggtggtggtg gtgatggcgc
     2461 tgcgcgccta cctcgagacc ggcaacgacc acgtcgacct gcccggcgac gcctcgcccg
     2521 aggccaccga ggacgactgg aaactgcgcg ggcgcaagcc ggcgccggca ccgggcggtc
     2581 gcggggggcg cgcatgaacc acctgctgat cctccccatc ctgctgccgg cggtggtcgg
     2641 cgcgctgctg gtgctggccg cgcgccacga cagcgtgctc gcacgcagct tcgcggtcgc
     2701 ctccaccgtg ctgatgctgg gcatcgccgt cgcgctgctg gtgctcgcga gcgacggcca
     2761 ggtgcgcagc tacgcgctcg gcgcctggcc ggcgcccttc ggcatcgtgc tcgcgcttga
     2821 ccgcctgtcg gcgctgatgc tggtgctcac cgcggtgctc ggcctgggcg tgctgctgta
     2881 cgcgatcggc ggctgggacc agcgcggcaa gcacttccac ccgctcttcc agttcgagct
     2941 gatgggcatc aacggcgcct tcctgaccgg cgacttcttc aacctgttcg tgttcttcga
     3001 gatcctgctc atcgcctcct acgggctcat ggtgcacggc ggcggcgggc tgcgggtgaa
     3061 ggcgggcgtg cagtacgtgg tcaccaacct ggtcggctcc tcggtgttcc tgatcgccgt
     3121 gggcatgatc tacagcgtca ccggcacgct caacatggcc gacctcgcgc gcatcgtgcc
     3181 gcaggtggcg gcggccgacc aggcgctgct gcagaccggc gcggtgctcc tgctgctggt
     3241 gttcgcggtc aaggccgcgc tggtgccgct gcacttctgg ctgcccggca cctacgccaa
     3301 cgcgcccggg ccggtggcgg cgctgttcgc gatcatgacc aaggtgggag cgtattcgat
     3361 catccgcctc tacgtgctcg ccttcggcgc cgacgcgggg gccgctgcct ggctcgcggc
     3421 gccctggctg ctgccggcgg ggctggtcac cctcgtgctg ggcatgaccg gcgtgctggc
     3481 cgcgcgcagc ctcggccaga tggcaagctt cgcggtcatc ggctcgatgg gcatgctgct
     3541 cgccacggtg gcggtattca cgccgcaggc gaccagcgcc gcgctgtact acctgatcca
     3601 ctccacgctc gcggccggcg cgctcttcct cgtcgccgac ctcgtcgccg agcgccgcgg
     3661 cgcccagcgc gaccgcttcg ccgcggcccc gcgcatcgcc cagggcgggc tggtgggcgg
     3721 gctgttcttc gtcgccgcga tcgccatgac cggcatgccg ccgctgtccg gcttcatcgg
     3781 caagctgctg gtgctcgacg gcgtgcgcgc ctcggcgcat gcgagctggt tctgggcgct
     3841 gatcctgtcg acctcgctga tcgccatcgt cggcttctcg cgcgccggca gcttcgtgtt
     3901 ctggaaggcg cacgcgctgc ccgccgcgcc cgcgcccggc tatcgcccgg acggcgcgct
     3961 gtccttcgtc gcggtcggcg ggctgctcgc ctgcctggtg ctgctgaccg cgttcgccgg
     4021 cccggtgcat gcctggctcg agctcgtcgc ggcacagctc tacgccccgg caggctacat
     4081 cgacgcggtg ctcggcaccg cacagggggt gcgctgatgg gcgccaggca cgacaggctc
     4141 gacgagcgca ccttcatgga gcgctggctg ccgcatccct tgatgaccgc ggtgctggtg
     4201 ctgctgtgga tgctgctgct caacagtttc agcttcggcg gcctgctggt gggcgtggtg
     4261 ctcgccgtgg tgatcacgcg ggtgacgagc aacttctggc cggagcgccc gccggtgaag
     4321 tcgtggtcga aggccttcgc ctacctcggc gtggtggcct gggacgtggt ggtcgccaat
     4381 ctccaggtca cccgcctgat cctgttccgc ccggtggaga gcctggcgac gcgctgggtc
     4441 gtgctgtcgc tcgagctgcg ctcgccggag gcgatcacgg tgctcgccgg caccatcacg
     4501 atgacgcccg gcacggtgtc ctgcgacctc tccgccgacg gccgcagcct gctggtgcac
     4561 tgcctcgacg cgcccgacgc cgaggacacg gtgcggcaga tgaaggaacg ctacgaggac
     4621 cgcctcaagg agatcttccc gtgatcgaat acgccctgca gttcggcttc gccgccgcct
     4681 cgctcgcgct gctgctcaac ctgtggcggc tgttgcgcgg ccccgcgctg atggaccgcg
     4741 tgctcgcggt cgacaccatg gtgatcaaca tcatcgcgct gatcgtgctc gcgggcatcc
     4801 acgagcgctc cacgatcttc ttcgaggccg cgctgctgtt cgcgatgttc ggcttcatct
     4861 ccaccgtcgc ctactgccgc ttcatcctgc gcggcgacgt catcgagtga gcggggaccg
     4921 cccatgacct tcgtgctcga actcctcgtc tcgctgctga tcgtcggtgg cggcgccttc
     4981 ctgctgatcg gctcgatcgg catggtcaag ctgcccgacc tgctcacccg cctgcacgca
     5041 cccaccaagg cgaccaccct gggggtgggc ggtgcgctgg tcgcctccat ggtgttcttc
     5101 gccgggctgg agggcacgct gtcgatccac gaggtgctga tcaccgcctt cctgttcatg
     5161 accgcgccga tcagcgccca cttcatcgcc aaggcccacc tgcacgaaca caccgagctg
     5221 cgcgacggcc tcccgcccac cggccgcccc gtcggctgga gcaccttcga cgccgcgccc
     5281 ggcgccggcg aggccgacga ggacgacggg cgccgcggcg cgcacgactg agcctgtcga
     5341 tcggcgataa tgcggcctcg aacccccggg gaatcacgtt gaacaccatc cgcagaaagc
     5401 cgcccacccc tcaaccctcg cgcatccagg gcacgctcgg cgtgcgcaag tccgcggacg
     5461 aagagccgtc ggccgaggaa gcgccctccg cgcgggatcc ggcggccgat gcgcgcacgc
     5521 cgcgcggcga ggccccggca cgtcctgccg gcggcgaggg acctgggcgg cggcccgggc
     5581 gagcgacgaa gcctgaacgg aacgagcgcg ccccgcgccg ggacgatggc gccaggccgg
     5641 gtcggcgcga agaggacgcg aagccggcgc gcggcgaacg cgcggcgcgc agcgcgggca
     5701 cgtccgcgcg cgacgacgag cgccccgcgc gcggcgagtg gggaaggaag cgcgcggacg
     5761 acgagcgcgc cccgcgccgc gagtccgcgc cggcccgcag ggacgacgga cgcgcggcgc
     5821 cgcgcgcgtc gggcccgaag cgcagggacg aggagcgctc ccagcgccgc gacgccgcgc
     5881 cgcagcgccg gggcgagcag gcgccgcctg cggccgccgc ggcctcctac gaggcgcgcg
     5941 ccgcttccgc ggccgccatc gccgaagccg cgcaggcgcg tgccgccgtc gaaggggtgc
     6001 ggctttccaa gctgatggcc gagcgcggcc tgtgctcgcg ccgcgaggcc gacgagttca
     6061 tcgagcgcgg ctgggtcttc gtggatggcc ggcgggtctc ggagctcggc gtgcgcgtcg
     6121 gccaggacgc ccgcatcacc ctcgcccccg aggccgcgcg cacccagcag cagcgtgcga
     6181 ccatcctgct gcacaagccg gtcggttacg tctccggcca gcccgagccc ggctacgccc
     6241 ctgcggtgag cctgatcggc cccgacaacc aggccgaccg cgacaccgcg cagcgcttcc
     6301 atcccagcca cctgaagaac ctcgcccccg cgggccggct cgatatcgac tccaccggcc
     6361 tgctggtgct gacccaggac ggccgcgtcg cccgccagct catcggcgag gactccaagg
     6421 tcgagaagga gtacatcgtc cgcgtcgagg gcacgctggc cgagaacgga ctcgcgctgc
     6481 tcaaccacgg cctgtggctg gacgaccgcc cgctgcgccc ggccgaggtg gagtggatca
     6541 acgacgagca gctgcgcttc gtcctgcgcg agggccgcaa gcgtcagatc cgccgcatgt
     6601 gcgagctggt ggggctgaag gtggtgggcc tcaagcgcgt gcgcatcggc cgggtgaagc
     6661 tgggcgacct gccgctgggg cagtggcgct tcctgcgcga ggacgagcgc ttcggctgag
     6721 gtgggatgga gcgcagtggg tgcgtagggg cgtctgcggc gcaatgcgtt tttgccgcag
     6781 gcgcgatgca agtcgcgatc ctgcggtgcc gcggcgttcg gcaaggtcga tgcggaaatg
     6841 ccgcaatcgt gacttgcgtc gcccttacct cccaacccgg gcgccgtgct tgggcggaga
     6901 ggtttccggg tccgcctcgg caagcgcctc cgcctccgcg agcgcgtccc cgagcgctcc
     6961 ggtgagcggc gcgatgcccg agcggtgcgc ggcgcgcgcc atggcgtggg cggcgagcgg
     7021 cgcggtggcg agcaggacga gcatcgcgaa cagcgcggcg agcgcgaagc cgccctcgct
     7081 cgccgcagcc acgccggcga ggatcagcgc ggcgcccagt gcgccggcct tgctggcggc
     7141 gtgcaggcgg gtgtagctgt cgggcaggcg cagcacgccg atcgcaccga tgaggccgat
     7201 cgacgcgccg agcagcagca gggccgcgga cagccaggcg aggagtccgc tcattgggca
     7261 gcctccccgt tcgcgcgcgc ttcccgtatc cggcgagccg gagccgcgcc tccacctgtg
     7321 cgggtctccc gcgcctcagg ctccgtcccg ggcgcttgcg cgctcgtgct gccgggcgcc
     7381 gcgccggctg cgagcagcct cgcatccgcc ccggtcgcag cctcgtccgc cccacggccg
     7441 cggcggcgga acagcaggat gaaggcggtg gtgccgagga aggacaccag ggacagcacc
     7501 accgcggcgt cgagcagcat gggctgggcg gtggccagcg cgagcagggc gatcgcggcg
     7561 atggcgatca tgctgagcgc gtcgatcgcc accacgcggt cgggcgcgcg cggcccgcgc
     7621 accaggcgca gcaggatcag cgcggcgccg agggcgagca gcgcgaaggt gagcggcagc
     7681 acccaggccg cccccgcgat tgcggcgttc atgtcgtgtc cctcccggtg ccgtccgcag
     7741 cgacgtccgg cgcgccggcg tcgagccagc gcagcaggcg gcgctcgatc gcgcgcaccc
     7801 cggcctccac ctcggcggcg gtgcgcgcat cgagcgcgtg gatgtacatc aggccggatt
     7861 ccggccggta gtcgagcgcc atcgtgcccg gcgtcagcgt cagcaggcag ccgagcaggg
     7921 tggcgaagcg ctcgtcccgg cgcgccaggc gcatcgccac cacggccggc tgcggcgcca
     7981 cctcgcggcc gagcacgatg cgcgcgacgc ccacgctggc gcggaagatc tcgccgacga
     8041 accacagcgc gaacgcggtg ccgagctcga gccggcgcag gtagcggcgg atgccgagga
     8101 ggtcgatcgc caggcgcagc gcgaggtaga ccgcgacgaa ggcggcgaac acgccgagtg
     8161 gccgcagcgc gtcggcgtag gcggccagtc cgaccgcgag caggaggtgc agccccagca
     8221 tgctcagttc cctcccgcgc gcacgaccgc gtcgatatag gccgccgggg cggcgagctg
     8281 ctccgccgcg gccaccgcgt agtccatcac cggcccggcc gcgaggccga tcgccaccgt
     8341 catcgccgcc agcgtgccca ccgcccacag cgcgggctgc agcccgtccg cgctgcgcgg
     8401 gctgcctcca cctccgctcc cgccgcccgc tccgcccgga tgcggcttga ggaaggcctc
     8461 gttccagatc ttgctcatcg acagcagcgt gaagatgccg gtgaccagcg ccaccgcggc
     8521 ggcgatccag gcgctcgcgt ccaggctcgc cttcaccagc acgaacttcg cccagaagcc
     8581 cgacagcggc gggatgcccg ccagcgacag cgccgggatc gcgaacagca gcgccagcca
     8641 gggcgcgcgc gcgtaaagcc cgcccatcgc cgccaggcgc tccgagccgg tcaggcgcgc
     8701 ggcgatgccg ccgatgaaga acaggttggc cttcaccacg atgtggtgga tcaggtagaa
     8761 caccgcgccg gcgagcgcga gcggggtggc gatcgccagc cccaggatca tgtagccgac
     8821 ctggctgacg atgtggaagg acaggatccg gcgcacctcg acctgggctg cggcgccgag
     8881 cacgccgatc agcatggtcg cgcacgccac ccacagcagc acctcgtggg cgacccccgc
     8941 gtccggccag aacagggtga cgaggcggat cagcgcatac acgccgacct tggtgagcag
     9001 cccggcgaag agcgccgaca ccggcgtcca cgccacgtgg taggacgccg gcagccagcc
     9061 gaacaccggg aacagcgccg ccttgatcga gaacgcggtc agcatcagca ccaccgccgc
     9121 gtgcgcggtc gtcggcacct cgccagcggc gaaggcctgc gccagcagcg ccatgttgag
     9181 gctgccgctg gcgccgtaga gcatgccggc ggcgagcagg aacatcatcg tcgccaccag
     9241 gttgagcacc acatacacca cggtgcccga cagccggcgc ctgccgccgc ccagcaccag
     9301 cagcgcgaag gagcccacca gcagcacctc gaaccagacg tagaggttga acacgtcgcc
     9361 ggtgatgaag gcgccgcaca cccccaccag caggccgtgc accagcgggt ggaagtcgcg
     9421 gcaacgcgca gggtcttcgt cgcgcgccat cgcgaacacg atggtggcgg tgccgacgat
     9481 gccggtgatc gccaccatgg cggccgacag gcggtcgacg accagcgtga tgccgtaggg
     9541 cgcggcccag ccgccggcct ggctggcgag gatctgcccc tgcgcggcga ggcctaccag
     9601 cgccagcccg gccgccgtga gtgccagcgc gccggccagg ctgatcgccg tcactgcgcg
     9661 cggcgagcgg cgcgcgagca gggtcgccac cagggtggcg agcgggatca gcagcgggga
     9721 gacgatgagc gtgttcacgc cttgtcccct tgcggcggca ggtccggcgc cggttcctcg
     9781 gcgaccgcgg tgacgaggtc ggtctcgatc ctgccgtgca gctcccagct gcgcttgagc
     9841 accgcgagcg cgaacacgaa gagcgcgaag ccgatcacga tcgcggtcag caccagggcc
     9901 tgtggcaggg ggttggcggc gagcgccggt gtgcccgcct cggtcacgaa ggcggcggcg
     9961 cggccgtcca gccgtcccgc ggagaacacc gccaggttca cgccgttgcc gagcacgacc
    10021 accccgagca ccacgcgcag cagcccgcgg tcgagcatca tccagatgcc gatcgcgacc
    10081 agcgcgccga cggtgagcga aacgaggatt tccatgttca gccctcccgc tcgagcaagc
    10141 cgagcagcat gtgcagcacc gcgccgagca cggtgaggaa gacgccgacg tcgaagagca
    10201 gcggcgtgcc cagcggcagc cctgcgggga agatccagtt gccggtgagg aagggctcgc
    10261 catggaagag accgaccagc ccggcgacgg ccgcgatgcc cagcccgccc gccagcatcg
    10321 ccagcggcgg cacgcgcagc agcgcgcgcg cccgcgtggt gccgaaggcg agcgccacca
    10381 gcaccgccgc gcacgccgcc accaggccgc cgatgaagcc gccgccgggc agattgtggc
    10441 cgcgccacag cagcatcagc gcgaccaggg cgagcagggc cgacagcggc aggatgccct
    10501 cgcgcagcag caccgagccg aagtccgcgc tgcccgcggt ggccccggcc gtcggtgcgg
    10561 cctcgtccgc ccgcctgccg ccggcgagca gcccggccgc agccagcccg gcgagaccga
    10621 cgacgaggat ctcgccgagc gtgtcgagcg cgcggaagtc caccaggatc acgttcacca
    10681 cgttggcgcc ctggccgccc ggcaggctgt tgtccagata ccagcgcgcg atgtcgccgg
    10741 gcagcggctg gctcaccgtc atcagcatca tcgccgccac caccgcgccg atcacgaccg
    10801 ccaccacggc gtggaagcgc ttcgccgccg gcttgcgcga gcccaccagc cgggtcggcg
    10861 gcaggcggcg cagcaccagg gcgaggaaga tcaccgtcag ggtctcgacc atcagctggg
    10921 tgatcgccac gtcgggcgcg cgcgcggcga ggaagaacat cgccatgccc agcccgctcg
    10981 cccccagggt ggcgaccagc gccacccgcc cgggggtcgt cgcggcggcc gccgcacccg
    11041 cgaccgcaag cacgcagccg agcagggcgg cgaggttgac cgggctggtg gcctgcggcc
    11101 aggcgaagtc gtcgccggtc gatgcgaaca gcccgatcag cgcgaagccg gcgatcgcca
    11161 gcaccagcgc gctgatgtgc tggcgcagcg agccgtgctg gaagcggtcg gccacccgcg
    11221 tggcgaaggc gaacacgcgc ttcagcaggc ggtcccagat gcggtcgccg ctcacccgcc
    11281 acagtacccg ccacagcgac agccggcggc gcagccgggt gcgctgcagg tagaagaaca
    11341 cgcccagcgc cacggtgagc aggctggcga gcagcgccgg ggtgaagccg ccccacagat
    11401 acaggctcac cggcaccgtg gcgcgcgaca ctgcctgcac cgcggcgtcg atcagccaga
    11461 cctcggcgag gttgttgaag gcgccgaaca cgaagccgcc gatcgccagc agcatcggcc
    11521 cgatccacat cggcacgccg acctcgtgcg gcgcgtgcgg gtagcgcccc tcccggccga
    11581 ggaaggcgcg cacgaagacg agcccggcgg cggtgagcag cagcgcgttg gtgaggatca
    11641 tcaccgcagt ggtgatccag cccgcgaggc cgagctcgat cagcccggcg tacttgaact
    11701 ccttggcgat gaagccgaag aagggcggca ggccggcgtt ggagaacgcg gccagcgcca
    11761 ccgcgaagcc ggtgagcggc atgtgcctga tcaggccgcc gagcagcgcg atctggcgcg
    11821 tgccggtggc gtggtcgatc gagcccaccg ccatgaacag cgcggccttg tagagggcgt
    11881 gcgcgaccag gtagatcgcg aaggcctgca ggccatagtg ggtgtcggtg ccgagcagca
    11941 tggtgagctg gccgagcacg gtgaccgtgg tgtaggcgag cacgcgcttg aggtcggtct
    12001 ggcggatcgc cagcaccgca ccgacgagcg cggtggcggc gccgatggtg atcaggatcg
    12061 tgctccagct cggcgagccg ccgagcgccg ggttgaggcg ggcgaggagg tacaccccgg
    12121 ccttcaccat ggtcgccgag tgcaggtagg ccgacaccgg cgtgggcgcg gccatcgcgt
    12181 tgggcaacca cagatggaag ggcagctgcg ccgacttggt gaaggcgccg atcagtacca
    12241 gcacgaggat cgccgggtag agcgcgtgcc cggcgatcgc ttcgcccgac agcccggaga
    12301 actgccagct gccgccgacg ttgccgagca ggatcaggcc ggcgagcagc gccagtccgc
    12361 cgccgccggt gatcagcagc gcctgcagcg ccgcgcggcg cgactcggcc ttgtcgtgct
    12421 ggaaggcgat gagcaggaag gaagtgacgc tggtcagctc ccagaacacg aacatcgcga
    12481 tcaggtcgtc ggccagcacc aacccgagca tcgccgccat gaagccgagc aggtaggcgt
    12541 ggaagcggcc gaggtggtgg tggtcggaga ggtaggtgcc ggcatagagc acgatcagcg
    12601 tgccgatgcc ggtgatgagc agcgcgaaca gcagcgacag gccgtcgagc cggaaggcga
    12661 gctcgacccc cagcgccggc acccaggcga gggtcgaggt gatgaccccg ccgccggcga
    12721 cggtcggcat ctgcgtcagg aagtggatga aggccgccag cggcgccagc gcgagcagcc
    12781 agcccgcacg ctgcccgagg cgggcggcaa gcggcaccgc ggccagcatc gcaagggcga
    12841 tcaggccgat gctggcaagc atgtcctacc ccggcaggtg ctggtcaaga agaaacctcc
    12901 cgaacgaagc ggtcgcgccg aacgagcgcg ccttgcgtat ggctttcggg aaactgaccg
    12961 cctgtttgcg ggccgggttc cgcaagtcgg cgggaggagg ggagaagcgg ggtcggacgg
    13021 aggtcgcggg tggggccgag ggggcgaaga ggagaggggg gcgaaagagc ggagagggcg
    13081 taaacggcgc tccccgccat tgcggcgggg agcgtggatg ccggggctgg gccgggcgct
    13141 agtgcgcgtg gtgggcgacg cgcggctggc cgtgcgcgcc gatctccggg tgagcttcgt
    13201 agaggccgct ctggcgggcg aagcagccgt tcaacgggca cttctggccg ggcgggcagc
    13261 catgttcgag agcgcattcc ctgcgggttt cgtccagcaa caccatttca ttcatggctt
    13321 cgcaacgggc gatcggggcg tcgaatgtac acatgatggt ctccttcctg cgtcgcggtc
    13381 tccggtcgct agagtgggaa aaccgtgact tatttcacga actgttcgat tccactctag
    13441 gtgtttgttg cgggaatgca tcgtgaatat gagtgaaggt tgacctgcgt caatctttgg
    13501 tcttcctttc ccccgaatgc ccgccaccct atccttcatg caggagcgcc ggcaggcgcg
    13561 aaagcggcgt gcgggtccct tccagcgccc ccgccatcca agcgccccat tcgcggctgc
    13621 cgccgctcct acaggggctg ccggaagcgc gacggttcat gtaggagcgc cggcaggcgc
    13681 gaaagcggcg tgcgggtccc ttc
//
LOCUS       DAOTIN010000085        13266 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_5590_length_13266_cov_9.248429, whole genome shotgun sequence.
ACCESSION   DAOTIN010000085 DAOTIN010000000
VERSION     DAOTIN010000085.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 13266)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 13266)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13266
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5590_length_13266_cov_9.248429"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(179..5074)
                     /locus_tag="P5537_12130"
     CDS             complement(179..5074)
                     /locus_tag="P5537_12130"
                     /inference="COORDINATES: protein motif:HMM:NF024487.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3320 domain-containing protein"
                     /protein_id="HRV78831.1"
                     /translation="MPDHTPSPVSRALDAARRKLLETGTRNRLIHVNRANARANCLNV
                     INERADEVFSILRLQGRRMRFRALGKDKADAAGEVPLALAEAAPDEDSGRLTDHFLET
                     PLGPDALARRLLRLAGDARTAEEEQGVNLLYLALGFLRWKEAPSSDVVREAPLVLLPV
                     QLVRNERSSTFDLVCREDDLSTNLPLQERLRQDFAIGLPEVDEAEGWTPAQYFALVRE
                     ATAGQRGWSVDADGMQLGFFSFAKLLMHRDLDPANWPEDAFAANPLLQGLLADGFEAD
                     APLFGPHDRLDALLDPARIIQVVDADASQTKVIEEVRHGASLVVQGPPGTGKSQTITN
                     LIAAAAHDGKSVLFVAEKMAALSVVHDRLVKAGLRDVCLELHSRTANKKALALELGRT
                     LSASAQALPEVGDPARLRRTRDELNRIAELLHAALPPSGQTPFRALAEIVGFIGKGAP
                     PPAIALDGLETLDGDAQAAALAAIAAHVGARARTGPPEQHPFRGTQAIDLQPPERSRL
                     QVELDAAVSELDALTAEAAAVAQALQQPAPESLAEVGALCAGLACLANPPTESPADAA
                     TTVPLLFAHAAQPRLLEGLQAGADWAAAQQAAAADFATAAWTADVAALRPALAKGQAS
                     FLYRIFGGYRRASAELATLLAAPLPGAAAERLALADRLLEVQARRRRLAEEEPALQAV
                     LGPEWRGERTPFAALLHAARWLATVRQATGFTRPAQLLGALAALPDPAGTAAALRQRA
                     AGCRERVHAPLARLHLDLAAAGIGEGGGAGGAAGGPDAGGGAALERAALAELRAACAQ
                     MAAAPAAYADWADLVRSIAAADQAGAGAIVRALREGCLEAARATEEFRYACAEARWNA
                     ARRASPELDALPALDRHALVGLFRTLEQERLEATRKLVLSRHFEQMPRGTVGEMGVIR
                     GEIGRKRGHKPVRWVMKNAGAMVQRIKPVMLMSPISVAQFLPPGSVSFDLLVIDEASQ
                     IRPEDALGVIARAHQIVVVGDQKQLPPTSFFDRLADDDADNDFDEDDTLPAGATAADM
                     ESILSLCEARGLRQRMLEWHYRSRAPSLIRVSNAEFYGDRLVLPPSPLQLDPDYGLKF
                     RRVPGLYARGGSGLGRQGTNRIEAEAVVRAMAEHARAWPELSLGVVAFSKAQADMLTE
                     VLELERRRDPVLDALLREGRAEDVFVKNIENVQGDERDVILISVGYGPQQAGGRLEAM
                     TFGPINGEGGERRLNVLFSRARVRCEVFASFDPGDIDPGRVSREGPRVLKRFLEFAQS
                     GILDERAPTGLGADSPFEEDVAAAIRALGYLADPQVGTAGFRIDVGVRHPERPGQYLV
                     AVECDGAAYHRAIWARERDRLRQDILENLGWRFHRIWSTDWFHHRAREIERLRSALEA
                     ARAATANGIRVRGANHGADRGQPHGEARVAARGEAREGPLDGSRDHSLAGTQALTRDA
                     ATADAADGHQNLPPSVSPDGGASFALDHLALVAPAYVRAAPAVRSSLEPHEAPASQLA
                     GLVAEIVAVEGPIHIDELARRIATAFGRARVGKRIAAAVEHAVGLALRQGAALVRAGD
                     FVMTPAQAESPPVRDRSAETGSLLKAASLPPIEITAAAALIRAESGAIAREELARATA
                     RLLGFQRLGPELAEAIRQALE"
     gene            5361..6314
                     /locus_tag="P5537_12135"
     CDS             5361..6314
                     /locus_tag="P5537_12135"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: protein motif:HMM:TIGR00254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor domain-containing diguanylate cyclase"
                     /protein_id="HRV78832.1"
                     /translation="MNSTCDPLPAQALRAEADDAVFERAYVEGLLRDRESLWHALFAQ
                     SRDGVVVLDEAGKVYETNQRFADLLGYTMDEMYQLHVWDWAHGLSPEDLRGMIRDIDG
                     DGHHFETQQMRKDGSLVDIELSNSCTFFRGQKLIFCICRDITARKAAERRIRYLATTD
                     TLTGASNRGEFSRRLAEEIARAHQHGTPLGLVMFDLDHFKRINDGYGHDVGDTVLRGV
                     TGVVRENVRLGDVIGRWGGEEFMLLLPKSDLAITLAVAERLRASIEARHFEPVERVTA
                     SFGVVVLERGEGFDALVKRADVALYRAKSAGRNRVETVSGD"
     gene            6730..7773
                     /locus_tag="P5537_12140"
     CDS             6730..7773
                     /locus_tag="P5537_12140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002928253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsJ-associated glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HRV78833.1"
                     /translation="MRVGINGMGRIGRLALRAAMGAAERGADDPRADNRLEVVHLNEI
                     KGGAAATAHLLAFDSVQGRWRADIRAEGEDAIRIDGRRLSFSAHSSAADIPWGELGVD
                     VVLECTGKILTPEALQGHLDRGAKRVIVAAPVKTGGVLNIVVGINHEAYDPARDRIVT
                     AASCTTNCLAPVVKVVHENLGIRHGQITTIHDPTNTNLVVDAPHKDLRRARSSLLSLA
                     PTTTGSATAIALIYPELKGKLNGHAVRAPVLNASLTDCVFELQRATTVEEVNALFKAA
                     AEGPLAGILGYEERPLVSVDYARDTRSSIVDALSTMVTDGTLLKVYAWYDNEMGYACR
                     MVDLACHMESVGL"
     gene            7776..9074
                     /gene="arsJ"
                     /locus_tag="P5537_12145"
     CDS             7776..9074
                     /gene="arsJ"
                     /locus_tag="P5537_12145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="organoarsenical effux MFS transporter ArsJ"
                     /protein_id="HRV78834.1"
                     /translation="MNEAPDSSPTPPASPAGGGAQHAARNYAIVTAAYWGFTLTDGAL
                     RMLVLLHFYRLGYSPFTLAFLFLLYEAAGVLANLVGGWLATHFGIARMLAVGLVTQIV
                     GFALLSALDPGWTAAMAVAWVVVAQGVCGVAKDLTKTASKSAIKITQAEAQGGSQGQL
                     FKWVAWFTGSKNAMKGIGFFLGGVLLETLGFRGALWTMAGLLALVLAGVLLSLPPMMG
                     RKKASRSVRELFAKSPGINVLAAARVVLFGARDVWFVVGVPVFLYSAGWTFTMVGTFL
                     AVWTIGYGLVQALAPQIVRRSADGLSHEVPAARLWSALLALIPVALAVAVWLRVPSLE
                     WVVVGGLGLFGFAFAVNSSVHSYLVLAYAGSEKAAEDVGFYYAANALGRFIGTLLSGL
                     LYQWGGLLYALIGSAVMLLVCWLATLALPLVRHESAQAAP"
     gene            9096..9329
                     /locus_tag="P5537_12150"
                     /pseudo
     CDS             9096..9329
                     /locus_tag="P5537_12150"
                     /inference="COORDINATES: protein motif:HMM:NF033788.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            9468..9980
                     /locus_tag="P5537_12155"
     CDS             9468..9980
                     /locus_tag="P5537_12155"
                     /EC_number="1.20.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030612 - arsenate reductase (thioredoxin)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase ArsC"
                     /protein_id="HRV78835.1"
                     /translation="MSDKCYNVLFLCAANSARSIIAEVILNQIGQGRFKAFSAGSAPR
                     GEVHPMTLQVLRAQGYDTGALRSKSWEEFAGPDAPQLDFVFTVCDTIAGETCPVWPGQ
                     PLTAHWGVADPVKVEGSEPRRLDAFSRTQNQLLNRLRLFTSLPLAKLDRLAIQHEIDR
                     IGQTPAAAEG"
     gene            9982..11013
                     /gene="arsB"
                     /locus_tag="P5537_12160"
     CDS             9982..11013
                     /gene="arsB"
                     /locus_tag="P5537_12160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018990473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008490 - arsenite secondary active
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACR3 family arsenite efflux transporter"
                     /protein_id="HRV78836.1"
                     /translation="MGLFERYLSVWVGLGILAGVGLGLFAPGAFQAIAGLEFAQVNLV
                     VAVFIWVMIYPMMIQIDWHAVKDVGRKPQGLILTLVVNWLIKPFTMAALGVLFFQHLF
                     APWVDPASASEYIAGMILLGVAPCTAMVFVWSQLVKGDPNYTLVQVSVNDLIMVFAFA
                     PIAAFLLGVTDLTVPWETLLLSTVLYVVLPLLAGMATRHVLERRSKQAVGEFVGRLKP
                     WSIVGLIATVVLLFGFQARTIVEKPLVIGLIAVPLLVQTYGIFLIAYLAAKAMKLPHD
                     VAGPACLIGTSNFFELAVAVAISLFGLNSGAALATVVGVLVEVPVMLSLVAIVNRTRH
                     WFAPAGAPT"
     gene            11534..13006
                     /locus_tag="P5537_12165"
     CDS             11534..13006
                     /locus_tag="P5537_12165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HRV78837.1"
                     /translation="MDATLLSWTMALLYGGLGNLAAYLAAHVLLCLLPAFFIAGAMSA
                     LIPKETITRFLGRNSSKTVSYPAAAAAGSLLAVCSCTIVPLFAGIYKKGAGLGPAITF
                     LFFAPAANILALVYTGGIIGPDLAIARFVLSLTFGIGIGLIMALLFRADDAAHDLATD
                     SAFGAQGAGMGRMALVFLFVWVALLLAGTLKLDVLTGTYLNFDLAVGDAQGWQAALDR
                     LVPYDAAKGEEGVSVQGVVLIALLTSIGYAAWRGFENISEGANAWTWISLALIAATLL
                     VAALAVQPVAGGLRIGLTGKFFGVAAALAVLGHIVRHRLSEDELRDWLWESWRFVKQI
                     FPLLVVGVFVVGMIRVLIRPEWIELLAGTNSLAGNLAGVVFGVFMYFPTLVEVPIAKM
                     FLELGMHRGPLLAYLMSDPELSLQSILIISAIIGRRKTFTYVGLVALFSAAAGLIYGA
                     WIDGAALFSLALYLAGFIAALVVLLSIASRRSAASSLKGV"
     gene            13009..13248
                     /locus_tag="P5537_12170"
     CDS             13009..13248
                     /locus_tag="P5537_12170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HRV78838.1"
                     /translation="MLSIKVLGPGCANCRKLEEIVHEAVAATGVQAEVVKVTDMGEIV
                     AYDVLKTPGLVINEKLVSSGRIPTAATIAEWIRAA"
BASE COUNT         1757 a         4493 c         4936 g         2080 t
ORIGIN      
        1 cgtcgcgctc tcggccgccg cattcgcgcc tgccggcgct cctacatgaa ccgtcgcgcg
       61 tccggggtgt ttccgcgccc gacgcggctg cacggcccgc cgcgcccttg taggagcggc
      121 ggcagccgcg aattgggcgg tcgatcgacc gcgggcatat tggcggctgc gatgccccct
      181 attccagcgc ttgccggatg gcctccgcga gttccgggcc gaggcgctgg aagccgagca
      241 ggcgggcggt ggcgcgggcg agctcctcac gggcgatcgc cccgctctcg gcgcggatga
      301 gcgcggctgc cgcggtgatc tcgatgggcg gcaggctggc agccttgagc aggctgccgg
      361 tctcggcgct gcggtcgcgc acgggcgggg attcggcctg ggcgggggtc atcacgaagt
      421 cgccggcgcg caccagcgcg gcgccttgcc gcagggcgag gccgacggcg tgctcgaccg
      481 cggcggcgat gcgcttgccc acgcgcgcgc ggccgaaggc ggtggcgatg cggcgggcga
      541 gctcgtctat gtggatcggg ccttcgacgg cgacgatctc ggcgaccagc ccggcgagct
      601 gcgaggcggg cgcctcgtgc ggctccaggc tggagcgcac cgccggcgcc gcgcgcacat
      661 aagccggggc gacgagtgcg aggtggtcga gcgcgaagga cgcaccgccg tcgggcgaca
      721 cggatggcgg gaggttctgg tgtccgtccg cggcatcggc cgtggcggcg tcacgcgtca
      781 gggcctgtgt cccggcgagg gagtggtccc ggctgccgtc cagcggtcct tcgcgcgcct
      841 cgccgcgggc cgcgacccgt gcttcgccgt gaggctggcc ccggtccgcg ccatggttcg
      901 cgccgcgcac gcggatgccg ttcgcggtgg cggcgcgcgc agcctccagc gcgctgcgca
      961 ggcgctcgat ctcgcgcgcg cggtggtgga accagtcggt gctccagatg cggtggaagc
     1021 gccagccgag gttctccagg atgtcctggc gcaggcggtc gcgctcgcgc gcccagatcg
     1081 cgcggtggta ggcggcgccg tcgcactcga ccgccaccag gtattgcccg gggcgctcgg
     1141 ggtggcgcac gccgacgtcg atgcgaaagc ccgccgtgcc gacctgcgga tcggcgaggt
     1201 agccgagcgc gcggatcgcc gcggcgacgt cctcctcgaa ggggctgtcg gcgcccaggc
     1261 cggtgggagc gcgctcgtcc aggatgccgc tctgcgcgaa ctcgaggaag cgcttgagca
     1321 cccgcggccc ctcgcggctg acgcggccgg gatcgatgtc gcccgggtcg aaggacgcaa
     1381 acacctcgca gcgcacccgc gcgcgcgaga acagcacgtt cagccggcgc tcgccgcctt
     1441 cgccgttgat cggtccgaag gtcatcgcct cgaggcggcc acccgcctgt tgcgggccgt
     1501 agccgaccga gatcaggatc acgtcgcgct cgtcgccctg cacgttctcg atgttcttga
     1561 cgaagacgtc ctcggcgcgg ccctcgcgca gcagggcgtc gagcaccggg tcgcggcggc
     1621 gttcgagctc gagcacctcg gtgagcatgt cggcctgcgc cttggagaaa gcgaccacgc
     1681 cgagcgagag ctcgggccag gcgcgcgcgt gctcggccat cgcccgcacc accgcctcgg
     1741 cctcgatgcg gttggtgccc tggcggccga gcccgctgcc gccgcgcgca tacagcccgg
     1801 ggacgcggcg gaacttgagc ccgtagtcgg gatcgagctg cagcggcgag ggcggcagca
     1861 ccaggcggtc gccgtagaac tcggcgttcg acacccggat cagcgagggc gcgcgcgagc
     1921 ggtagtgcca ttcgagcatg cgctggcgca ggccgcgcgc ctcgcacagc gacaggatgc
     1981 tctccatgtc ggccgcggtg gcaccggccg gcagggtgtc gtcctcgtcg aagtcgttgt
     2041 cggcgtcgtc gtcggcgagg cggtcgaaga aggaggtcgg cgggagctgc ttctggtcgc
     2101 ccacgacgac gatctggtgc gcgcgcgcga tcaccccgag cgcgtcctcg gggcggatct
     2161 gcgaggcctc gtcgatcacc agcaggtcga agctcacgct gccggggggc aggaactgcg
     2221 cgaccgagat cgggctcatc agcatgaccg gcttgatgcg ctgcaccatg gcgccggcgt
     2281 tcttcatcac ccagcgcacc ggcttgtggc cgcgcttgcg cccgatctcg ccgcggatca
     2341 cgcccatctc gcccacggtg ccgcgcggca tctgctcgaa gtggcgcgac aggacgagct
     2401 tgcgcgtggc ctcgaggcgc tcctgctcaa gcgtgcggaa gagccccacg agcgcgtggc
     2461 ggtcgagcgc gggcagggcg tcgagctcgg ggctggcacg gcgggcggcg ttccagcgcg
     2521 cctcggcgca ggcgtagcgg aactcctcgg tcgcgcgcgc ggcctcgagg cagccctcgc
     2581 gcagggcgcg cacgatcgcg cccgcgccgg cttggtcggc tgcggcgatg ctgcgcacga
     2641 ggtcggccca gtccgcgtag gcggccggcg ccgcggccat ctgcgcgcag gcggcgcgca
     2701 gctcggcgag cgcggcgcgc tcgagcgccg cgccgccgcc cgcgtcgggg ccgcccgcag
     2761 cgccacccgc accgccgccc tcgccgatgc cggccgcggc gaggtccagg tgcaggcgcg
     2821 cgagtggggc gtgcacgcgt tcgcggcagc ccgcggcgcg ctggcgcagg gcggcggcgg
     2881 tgcccgccgg gtcgggcagg gccgcgagcg cgccgagcaa ctgggcgggg cgggtgaatc
     2941 cggtggcctg gcgcaccgtg gccagccagc gcgcggcgtg cagcagcgcg gcgaagggcg
     3001 tgcgctcgcc gcgccattcc gggccgagga cggcctgcag cgcgggctct tcctcggcga
     3061 ggcggcgccg cctcgcctgg acctcgagca ggcggtccgc cagggcgagg cgctcggccg
     3121 ccgcgccggg cagcggcgcc gccagcaggg tggcgagctc ggccgaggcg cgccgatagc
     3181 cgccgaagat gcggtacagg aaggaggcct gccccttggc cagcgccggg cgcagcgcgg
     3241 ccacgtcggc ggtccatgcc gcggtggcga agtctgcggc ggcggcctgc tgcgccgcgg
     3301 cccagtcggc gccggcctgc aggccctcga gcaggcgggg ctgcgcggcg tgggcgaaga
     3361 gcagcggcac ggtcgtggcg gcgtccgcgg gcgactcggt gggcgggttg gcaaggcacg
     3421 cgagcccggc gcacagcgcg ccgacctcgg cgaggctctc cggcgccggc tgctgcaggg
     3481 cctgcgcgac cgccgccgcc tcggccgtca gcgcgtcgag ctcggacacg gcggcgtcga
     3541 gctcgacctg caggcgcgag cgctcggggg gctgcaggtc gatcgcctgc gtgccgcgga
     3601 agggatgctg ctcgggtggg ccggtgcgcg ctcgcgcgcc gacgtgggcc gcgatcgcgg
     3661 ccagcgcggc ggcctgggcg tcgccatcga gcgtctccag cccgtcgagc gcgatcgccg
     3721 gtggcggcgc gcccttgccg atgaagccga cgatctcggc gagcgcgcgg aagggcgtct
     3781 gtcccgaggg cggcagcgcc gcatgcagca gctcggcgat gcggttgagc tcgtcgcgcg
     3841 tgcggcgcag ccgcgccggg tcgcccacct cgggcaaggc ctgcgcgctc gccgacagcg
     3901 tgcggccgag ctcgagcgcg agcgccttct tgttggcggt gcgcgagtgc agctccaggc
     3961 agacgtcgcg cagcccggcc ttcaccaggc ggtcgtgcac caccgagagc gcggccatct
     4021 tctcggcgac gaacagcacc gacttgccgt cgtgcgcggc ggcggcgatc aggttggtga
     4081 tggtctgcga cttgcccgtg ccgggcgggc cctgcaccac caggctggcg ccgtggcgga
     4141 cctcctcgat gaccttggtc tgcgaggcgt cggcgtcgac cacctggatg atgcgggcgg
     4201 ggtcgagcag cgcgtcgagg cggtcatgcg ggccgaagag cggcgcgtcg gcctcgaagc
     4261 cgtcggcgag caggccctgc agcagggggt tggcggcgaa cgcatcctcg ggccagttcg
     4321 ccgggtcgag gtcgcggtgc atcagcagct tggcgaagga gaagaagccg agctgcatgc
     4381 cgtcggcgtc caccgaccag ccgcgctggc ctgcggtcgc ctcgcgcacc agggcgaaat
     4441 actgcgccgg cgtccagccc tcggcctcgt ccacctcggg caggccgatc gcgaagtcct
     4501 ggcgcaggcg ctcctgcagc ggcaggttgg tgctgaggtc gtcctcgcga cacacgaggt
     4561 cgaaggtcga gctgcgctcg ttgcgcacga gctgcaccgg cagcagcacc agcggcgcct
     4621 cgcgcaccac gtcggaggag ggcgcctcct tccagcgcag gaagccgagc gcgaggtaga
     4681 gcaggttcac gccctgttcc tcctcggccg tgcgcgcgtc gccggccagg cgcagcagcc
     4741 ggcgcgcgag cgcatcgggg ccgagcggcg tctccaggaa gtggtcggtc agccggcccg
     4801 agtcctcgtc gggcgccgcc tccgccaggg ccagcggcac ctcgccggct gcgtcggcct
     4861 tgtccttgcc gagcgcgcgg aagcgcatcc ggcgcccctg caggcgcagg atcgagaaca
     4921 cctcgtcggc gcgttcgttg atcacgttga ggcagttggc gcgtgcgttg gcgcggttga
     4981 cgtggatcag ccggttgcgc gtgccggtct cgagcagctt gcggcgcgcg gcgtcgaggg
     5041 cgcgggagac gggagagggc gtgtggtcgg gcatcggcga gggcggggag ggctggcggg
     5101 agggagcgag cccaggattg tcctgcagga tcggctttcg ctccaccgcg ttgcgctgga
     5161 gtcggggcgc ggcggagcgc cgcgaggggc tgcgccgcgg gagcaaacat caaaaaaatg
     5221 ttaaagcaca aaaacagcaa aaaagccttg cagtgtgaaa taggtaaccg acgaaccggg
     5281 cgcgcagggg gatactttgc ccaccctggc aggccgcatc cggcggcccg cgtgcagcca
     5341 agcttcggac ctgagtctcc atgaacagca cctgcgatcc tctgccggca caggccctgc
     5401 gcgccgaggc ggacgacgcg gtgttcgagc gcgcctacgt cgaaggcctg ctgcgggatc
     5461 gcgaatcgct ctggcacgcc ttgttcgcgc agtcgcgcga cggtgtcgtg gtgctcgacg
     5521 aggccggcaa ggtctatgag accaaccagc gcttcgccga cctcctcggc tacacgatgg
     5581 acgagatgta tcagctccac gtgtgggact gggcgcatgg cctcagcccc gaagatctgc
     5641 gcggcatgat ccgtgacatc gacggcgacg gtcatcactt cgagacccag cagatgcgca
     5701 aggacggcag cctggtcgac atcgagctca gcaacagctg caccttcttc cgcggacaaa
     5761 agctcatctt ctgcatctgc cgcgacatca ccgcacgcaa ggcggccgag cgtcgcatcc
     5821 gctatctcgc caccaccgac accctgaccg gagccagcaa ccgcggcgag ttctcgcgcc
     5881 ggctcgccga ggagatcgcc cgcgcccacc agcacggcac gccgctcggg ctggtgatgt
     5941 tcgacctcga ccacttcaag cgcatcaacg acggttacgg ccatgacgtc ggcgatacgg
     6001 tgctgcgcgg ggtgacgggt gtcgtgcgcg agaacgtccg cctcggtgac gtgatcggcc
     6061 gctggggcgg cgaggagttc atgctcctgc tgcccaagtc cgatctggcg atcacgctcg
     6121 ccgtcgccga gcgcctgcgt gccagcatcg aggcgcggca cttcgagccg gtcgagcgcg
     6181 tcaccgccag cttcggcgtg gtcgtgctgg agcggggcga gggcttcgac gccctcgtca
     6241 agcgcgccga cgtggcgctc taccgcgcca agagcgcagg ccgcaaccgg gtggagacgg
     6301 tgagcggcga ctagcccgac ggcatcccgc gcgggcggaa gttcttcgca tcctgcaccg
     6361 cccattcgcg gctgccgccg ctcctacagg ggcgtggtgg ttcgtgcatg ggcgttgcgg
     6421 acggataggc ttcggggtgt cattcgtgca tgggcgccgc ggacaggtag gcgtcggagt
     6481 gtcattcgtg catgggcgcc gtggggcggg cgcgcgccgg cggtgtagcg ggtcgtgggg
     6541 gcgtggcggg gcggagatgc ttcgcaggcg cggtggttcg tgtaggagcg ccggcaggcg
     6601 cgaacggggc tttccgctac cgatcgtctc cgaatcttcg catcgccgtc tccaaatctt
     6661 cacatcgccg taacgtcacc tcatctacac ttcaacgatt ctaaaaatgt tgatgagtag
     6721 gagcgcaaga tgagagtcgg gatcaatggc atggggcgga tcggtcgcct ggcgctgcgc
     6781 gcggcgatgg gcgcggcgga gcgtggggcg gacgacccgc gcgcggacaa ccgcctcgag
     6841 gtggtccacc tcaacgagat caagggtggc gcggcggcga ccgcgcacct gctcgccttc
     6901 gacagcgtgc aggggcgctg gcgggccgac atccgcgccg agggcgagga cgcgatccgc
     6961 atcgacggtc gcaggctgtc cttctcggcc cattccagcg cggccgacat cccctggggc
     7021 gagctgggtg tcgatgtggt gctcgaatgc accggcaaga tcctgactcc cgaggcgctg
     7081 cagggccacc tcgaccgcgg cgcgaagcgc gtgatcgtcg ccgccccggt gaagaccggc
     7141 ggcgtgctca acatcgtggt cggcatcaac cacgaggcct acgatcccgc gcgcgaccgc
     7201 atcgtcaccg cggcttcgtg caccaccaac tgcctcgcgc cggtggtcaa ggtggtgcac
     7261 gagaacctcg gcatccgcca cggccagatc accaccatcc acgaccccac caacaccaac
     7321 ctggtggtcg acgccccgca caaggacctg cgccgtgcgc gcagctcgct gctgagcctg
     7381 gcgcccacca ccaccggcag cgccaccgcg atcgcgctga tctacccgga gctgaagggc
     7441 aagctcaacg gccacgcggt gcgcgcgccg gtgttgaacg cctcgctcac cgactgcgtg
     7501 ttcgagctgc agcgcgcaac cacggtggag gaggtcaatg cactgttcaa ggccgcggcc
     7561 gagggcccgc tcgccggcat cctcggctac gaggagcgcc cgctggtcag cgtcgattac
     7621 gcccgcgata cgcgcagttc catcgtcgat gcgctgtcca ccatggtcac cgacggcacg
     7681 ctgctgaagg tgtacgcctg gtacgacaac gagatgggct acgcctgccg catggtggac
     7741 ctggcttgcc acatggaaag tgtcggcctc tgaagatgaa cgaagcgcca gactcttccc
     7801 cgacgccgcc cgcgtcgccc gcgggcggcg gcgcgcagca cgccgcgcgc aactacgcca
     7861 tcgtcaccgc cgcctactgg ggcttcacgc tcaccgacgg cgcgctgcgc atgctggtgc
     7921 tgctgcactt ctaccgcctg ggctactcgc cgttcacgct cgccttcctg tttctgctct
     7981 acgaggcggc gggcgtgctg gcgaatctcg tgggcggctg gctggcgacg cattttggca
     8041 tcgcgcgcat gctggcggtc gggctggtca cgcagatcgt cggcttcgcg cttctgtcgg
     8101 cgctcgaccc cggttggacc gcggcgatgg cggtggcctg ggtggtggtg gcgcagggcg
     8161 tgtgcggcgt ggccaaggac ctgaccaaga ccgcgagcaa gtcggcgatc aagatcaccc
     8221 aggccgaggc ccagggtgga agtcagggcc agctcttcaa gtgggtggcg tggttcaccg
     8281 gcagcaagaa cgcgatgaag ggcatcggct tttttctcgg cggcgtactg ctggagacgc
     8341 tgggttttcg cggcgcgctg tggaccatgg cgggcctgct tgcgctggtg ctggcgggcg
     8401 tgctgctgtc gctgccgccg atgatgggca ggaagaaggc ttcgcgctcg gtgcgcgagc
     8461 tgttcgccaa gagcccgggc atcaacgtgc tggccgccgc gcgcgtggtg ctgttcggcg
     8521 cgcgcgacgt ttggttcgtg gtcggcgttc cggtgttcct gtattcggcg gggtggacct
     8581 tcaccatggt cggcactttc ctggctgtgt ggacgatcgg ctacgggctg gtgcaggcgc
     8641 tggcgccgca gatcgtgagg cgcagcgccg atgggctgag ccacgaggtg ccggccgcgc
     8701 gcctgtggtc ggcgctgctg gcgctgatcc ccgtggcgct ggcggtagcg gtgtggctgc
     8761 gggtgccgag cctggagtgg gtggtggtcg gcggcctcgg gctgttcggc ttcgccttcg
     8821 cggtcaactc ctcggtgcat tcctacctgg tgctggctta cgcgggctcg gagaaggcgg
     8881 ccgaggacgt cggcttctac tacgccgcca acgcgctcgg ccgcttcatc ggcacgctgc
     8941 tgtcgggcct gctgtaccag tggggcgggc tcttgtatgc gctgatcggt tcagccgtga
     9001 tgctgctggt ctgctggctg gcgacgctgg cgctgccgct cgtgcgccac gaatccgccc
     9061 aggccgcccc ctgagggctt gctggagaaa catcgatgga caagaaagcc gccgtttccg
     9121 ccttcgaggc actgtcctcg ggcatccgcc tcgacgtctt ccgcctgctc gtgcgcgcgg
     9181 gaccgcaggg catggtggcg ggcgagctcg ccagcgcgct cgacctgccg ccgaccaaca
     9241 tgtccttcca cctcaaggcg ctggcgcagg ccgggctggt ggcggccgag caggagggcc
     9301 gcttccagcg ctaccgcgcc gacatggcgc ggatgcgcgg cctgatcgcc tacctcaccg
     9361 acgagtgctg cagcggcgtg cctgcgctgt gcggcgtcga tggcggcgcg gccacgaacg
     9421 gattttcccc gcccgaaccg ggcataaaac gacaaacgga gtcttccatg tccgacaagt
     9481 gctacaacgt gctcttcctg tgcgcggcca actcggcgcg cagcatcatc gccgaggtca
     9541 tcctcaacca gatcggccag ggccgcttca aggccttcag cgccggcagc gcgccgcgcg
     9601 gtgaggtgca cccgatgacg ctgcaggtgc tgcgggccca gggctacgac accggcgcgc
     9661 tgcgcagcaa gagctgggag gagttcgccg gccctgacgc gccgcagctc gacttcgtgt
     9721 tcaccgtgtg cgacacgatc gccggcgaga cctgcccggt gtggcccggc cagccgctca
     9781 ccgcgcactg gggcgtggcc gacccggtca aggtcgaggg cagcgagccg cgccggctcg
     9841 acgccttcag ccggacgcag aaccagctcc tcaaccgcct gcgcctcttc accagcctgc
     9901 ccctggccaa gctcgaccgc ctcgcgatcc agcacgagat cgaccgcatc gggcagacgc
     9961 cggccgccgc ggagggctga catggggctc ttcgagcgct acctcagcgt ctgggtgggg
    10021 ctgggcatcc tcgccggggt cggcctcggg ctgttcgcgc ccggggcctt ccaggccatc
    10081 gccgggctcg agttcgcgca ggtgaacctg gtggtggccg tgttcatctg ggtgatgatc
    10141 tacccgatga tgatccagat cgactggcac gcggtgaagg atgtcgggcg caaaccgcag
    10201 gggttgatcc tgaccctggt ggtcaactgg ctcatcaagc cgttcacgat ggcggcgctc
    10261 ggggtgctgt tcttccagca tctcttcgcg ccatgggtgg atccggcttc ggccagcgag
    10321 tacatcgccg gcatgatcct gctcggcgtg gcgccgtgca ccgcgatggt cttcgtgtgg
    10381 agccagctgg tgaagggcga tcccaactac accctggtgc aggtgtcggt gaatgacctg
    10441 atcatggtgt tcgcgttcgc gccgatcgcg gccttcctgc tgggcgtcac cgacctcacc
    10501 gtgccgtggg agaccttgct gctgtcgacg gtgctctacg tggtgctacc cttgctggcc
    10561 gggatggcga cgcggcatgt gctggagcgg cgctcgaagc aggcagtggg cgagttcgtc
    10621 ggtcgcctca agccctggtc catcgtcggc ctgatcgcca ccgtggtgct gctgttcggc
    10681 tttcaggcgc gtaccatcgt ggaaaaaccg ctggtgatcg gcctgatcgc ggtgccgctg
    10741 ctggtgcaga cctacggcat cttcctgatc gcctacctgg ccgcgaaggc gatgaagctg
    10801 ccgcacgacg tcgccggccc ggcctgcctg atcggcacct cgaacttctt cgagcttgcg
    10861 gtcgcggtgg cgatctcgct gttcgggctg aactccggcg cggcgctggc gaccgtggtc
    10921 ggcgtgctgg tggaggtgcc ggtgatgctt tcgctggtgg cgatcgtcaa ccgcacgcgg
    10981 cactggttcg cgcctgccgg cgctcctaca tgaaaccgtc gcggcttggg ggtgtgtagg
    11041 gattgggagg ggccactcgc ggttcggtgg gttgcgtgcg tggaggtcgg tacgcggttt
    11101 ggcgggttgt aggagcgccg gcaggcgcga atgcgggcgt gaatagcggc gggaatgcgg
    11161 gagcaaatgc gggagcgaag ccgggcacgt cgggcgattg ttcgaccgcc gcttttcgcg
    11221 cctgccggcg ctcctacatg aaaccgtcgt ggcacggggg gcgtgtaggg gttgggaggg
    11281 gccgcgcgcg gttcggcggg ttgcgtgcgt ggaggccggt acgcggttcg gggggttgta
    11341 ggagcgccgg caggcgcgaa tgcggccgtg aatgcgggag cgaagccggg catgtcgggc
    11401 gattgttcga ccgccgcttt cgcgcctgcc ggcgctcgta catgaaaccg tcgcggctcg
    11461 gggacgtgta gggggttggg agggccggca tgcggctcgg cgggctgcga ccgcggggga
    11521 atccggagga atcatggatg cgacgctgct gagttggacg atggccctgc tgtatggcgg
    11581 gctgggtaac ctcgccgcct atctcgccgc ccacgtgctg ctgtgcctgc tgccggcctt
    11641 cttcatcgcc ggcgccatgt cggcgctgat ccccaaggaa accatcaccc gcttcctcgg
    11701 ccgcaactcc agcaagacgg tgtcctaccc cgccgcggcc gccgcgggtt cgctgctggc
    11761 ggtgtgctcg tgcaccatcg ttccgctttt cgccggcatc tacaagaagg gcgcgggtct
    11821 cggtccggcg atcaccttcc tgttcttcgc cccggcggcc aacatcctgg cgctggtcta
    11881 caccggcggc atcatcgggc cggatctggc gattgcgcgc ttcgtgctgt cgctcacctt
    11941 cggcatcggc atcggcctga tcatggcgct gctgttccgc gccgacgacg ccgcgcacga
    12001 cctcgccacc gacagcgcct tcggcgcgca gggcgcgggc atggggcgga tggcgctggt
    12061 gttcctgttc gtgtgggtgg cgctgctgct cgccggcacg ctgaagctgg acgtgctgac
    12121 cgggacctat ctgaatttcg acctggccgt tggcgatgcg cagggctggc aggccgcgct
    12181 cgaccgcctg gtgccctacg acgccgccaa gggcgaggag ggcgtgtctg tgcagggcgt
    12241 ggtgttgatc gcgctgctga cctcgatcgg ctatgccgcc tggcgcggct tcgagaacat
    12301 cagcgaaggc gccaacgcgt ggacctggat cagcctggcg ctgatcgcgg cgaccctgct
    12361 ggtcgcggcg ctcgcggtgc agcccgtggc gggcgggctg cggatcggcc tcaccggcaa
    12421 gttcttcggc gttgccgccg cgttggcggt gctgggccac atcgtgcgcc accgcctgag
    12481 cgaggacgag ctgcgcgact ggctgtggga gtcgtggcgc ttcgtgaagc agatcttccc
    12541 gctgcttgtc gtgggcgtgt tcgtggtcgg catgatccgc gtgctgatcc gcccggagtg
    12601 gatcgagctg ctggccggca ccaactcgct cgccggcaac ctggcgggcg tggtgttcgg
    12661 cgtgttcatg tacttcccga ccctggtcga ggtgccgatc gcgaagatgt tcctcgagct
    12721 cggcatgcac cgcggcccgc tgctcgccta cctgatgtcc gaccccgagc tgtcgctgca
    12781 gagcatcctg atcatctcgg cgatcatcgg ccgcaggaag accttcacct acgtcggcct
    12841 ggtggcgctc ttcagcgccg ccgccggcct catctacggt gcctggatcg acggcgccgc
    12901 cttgttctcg ctcgcgctct acctcgcggg cttcatcgcc gcgctggtcg tgctgctgtc
    12961 gatcgccagc cggcgcagcg ccgcgtcctc actcaaggga gtctgatcat gctcagcatc
    13021 aaggtcctcg gccccggctg cgccaactgc cgcaagctcg aagagatcgt gcacgaggcg
    13081 gtcgccgcca ccggcgtgca ggccgaagtg gtcaaggtca ccgacatggg cgagatcgtc
    13141 gcctacgacg tgttgaagac gcccggcctg gtgatcaacg agaagctggt ctcgtcggga
    13201 aggattccca ccgcggcgac gatcgcggag tggattcggg cggcttgagg tccggccctg
    13261 cgggac
//
LOCUS       DAOTIN010000086        12934 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_5765_length_12934_cov_9.359655, whole genome shotgun sequence.
ACCESSION   DAOTIN010000086 DAOTIN010000000
VERSION     DAOTIN010000086.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 12934)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 12934)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12934
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5765_length_12934_cov_9.359655"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1587)
                     /gene="bamA"
                     /locus_tag="P5537_12175"
     CDS             complement(<1..1587)
                     /gene="bamA"
                     /locus_tag="P5537_12175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamA"
                     /protein_id="HRV78839.1"
                     /translation="MNRKLLPGLLVALFAASPALAFDPFVVKDIRVEGIQRTEAGTVF
                     NYLPVRVGETFTEAQAADAIRALFATGFFSDVRIETEGEVIVVVVDERAAIADITFDG
                     VKEFDKDALEKGLREVGLAESRIFDRSLLERAEQELKRQYLSRGKYAATVTTTVTPLE
                     RNRVGINFKVDEGGVAKIRQIRIVGAKTFEEDDLLDEMQLTTPGWLTWYTKNDQYSRQ
                     KLSADLETLRSFYLNQGYLDFNIDSTQVSITPDKQDIYITVNITEGEKYTVSGVRFTG
                     DLILPESEYQALTKIRPGETFSRERLTETTKAITDRLGNEGYAFANVNAAPEVDKVKR
                     EVAFTVFVDPGRRVYVRRINVGGNTKTRDEVVRREMRQMEGGWYDAEAINRSRTRIDR
                     LGFFDEVTVETPAVPGTTDQVDVNFSVKERPTGNLMLGAGFSSSENIVLSASIAQQNL
                     FGSGNALTLGLNTSESSRTLALSFTNPYYTVDGVSLGWDLYHRTYDADELDSVSPYKT
                     VSTGAGIRLGWPIAEDDQVNF"
     gene            complement(1596..2960)
                     /gene="rseP"
                     /locus_tag="P5537_12180"
     CDS             complement(1596..2960)
                     /gene="rseP"
                     /locus_tag="P5537_12180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HRV78840.1"
                     /translation="MTLFDYLIPFALALGLLILVHELGHYLVARWCGVKVLRFSIGFG
                     KPLLRRTAGRDGTEWVLAAFPLGGYVKMLDEREAPVAAPELHRAFNRQSVYRRFAIVA
                     AGPLANFLLAIALYWGLFVAGTEELKPRVTLSDTPAIAQAAGVREGDLVVAVDEEPVR
                     SWQDLRWVLLRHALDSREVMLRVRTLEDVEAFRRLDLSGVAIDEGGTDLIARLGLRPW
                     RPAIPAVIGRVADGSAAERAGLQDGDRVLAIAGTPVVAWSDLVRLVREAPGRALDFEV
                     ERGGEAVKLVITPEAAEEGGAQIGRIGVGVAEAAAGGIAMFGEVRYGVLEGLSRAVQQ
                     TWETSVLSLKMIGRMLTGEVSWKNLSGPVTIADYAGQTAQLGWTHYLKFVALISISLG
                     VLNLLPIPVLDGGHLLYYTIEIIKGGPIPERVMEVGQQIGLALLVMMMAFAFYNDLNR
                     LISG"
     gene            complement(2957..4159)
                     /gene="ispC"
                     /locus_tag="P5537_12185"
     CDS             complement(2957..4159)
                     /gene="ispC"
                     /locus_tag="P5537_12185"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0030604 - 1-deoxy-D-xylulose-5-phosphate
                     reductoisomerase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070402 - NADPH binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HRV78841.1"
                     /translation="MPDPAPQRLTVLGATGSIGQSTLDVVARHPDRFEVFALSAQRQG
                     DKLLDQCLRFSPRFAVLGDAAAAELLRAGLRAAGSDTEVLCGEEALERVAAAEVVDMV
                     MAAIVGAAGLRPTLAAARAGKKVLLANKEALVLSGQLLIDAVAASGAVLLPIDSEHNA
                     IFQALPADYGRQPARAGVRRVLLTASGGPFRSAPIEALADVTPEQACAHPNWVMGRKI
                     SVDSATMMNKGLEVIEAHWLFGAPAEMIEVVVHPQSVIHSMVDYADGSVIAQLGNPDM
                     RTPIANAMAWPERIDAGVRPLDLFEIARLDFERPDFGRFPCLKLAFDALRAGGTAPAV
                     LNAANEEAVAAFLDHRIGFLDIAAVIAASLERSRPGAVDSLEAVLSADAHARELARDE
                     ISRLRKNR"
     gene            complement(4205..5026)
                     /locus_tag="P5537_12190"
     CDS             complement(4205..5026)
                     /locus_tag="P5537_12190"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HRV78842.1"
                     /translation="MLKDRVLTAIVLLFGLLGAVFLLPASLWLVVCAALCGAAAWEWG
                     ALARFDHGLRVSTAVAFTAACALLGWSAGLGSGQLGGAGALVPLYVFSGLFWIFVVPL
                     WLRGKWALSNPMLASLVGFIVLVPTALAMMQLRTMGPWVLLGTMAVVWVADIAAYFSG
                     RAFGRHKLAPSISPGKTWEGAAGAAVAVLVFGFGMLAMRGAELQGGVAVIAGVLLAWT
                     AVSIVGDLFESLLKRQAGLKDSGSILPGHGGILDRIDSLTSTLPLVALGAVWLAR"
     gene            complement(5034..5801)
                     /gene="uppS"
                     /locus_tag="P5537_12195"
     CDS             complement(5034..5801)
                     /gene="uppS"
                     /locus_tag="P5537_12195"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl diphosphate synthase"
                     /protein_id="HRV78843.1"
                     /translation="MIGGLFRSSTRDIPDVSQVPQHIAVIMDGNGRWARKRMLPRVAG
                     HARGVEALRATVRGCVDRGVEYLTVFAFSSENWRRPQDEVSFLMQLFLKSLQKEIRRM
                     HDNDMRFRVIGDLSRFDGRLVDMIREAEALTAGNGGLNFTVAANYGGRWDILDAMSRL
                     MAREPGRLERFTEEELAAELSMSFAPEPDLFIRTGGEKRISNFLLWQLAYTELYFTDV
                     LWPDFDDEALGKAIGSYQARERRFGRTSEQLKADAGE"
     gene            complement(5854..6411)
                     /gene="frr"
                     /locus_tag="P5537_12200"
     CDS             complement(5854..6411)
                     /gene="frr"
                     /locus_tag="P5537_12200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011765639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HRV78844.1"
                     /translation="MISELKKNIEQKMQKSVEALKTDLAKVRTGRAHTGLLDHVMVEY
                     YGSMVPVNQVANITLIDARTIGVQTWEKPMLGKVERAIRDSDLGLNPANMGELLRVPM
                     PALTEERRRDLTKVVRHEGETAKVAIRNLRRDANQQLKDAVKDKEISEDDERRGEDEI
                     QKLTDRYVAEIDKLLAQKEQELMQI"
     gene            complement(6430..7149)
                     /gene="pyrH"
                     /locus_tag="P5537_12205"
     CDS             complement(6430..7149)
                     /gene="pyrH"
                     /locus_tag="P5537_12205"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015435991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HRV78845.1"
                     /translation="MNVSAAYKRILLKLSGEALMGDDAYGINEEVVSRIVSEVAEITR
                     LGVQVGVVIGGGNIFRGMKGAASGMDRATADYMGMLATVMNAMALADAMRRMDLEARV
                     QSALRIDQVVEPYIRGRAIRHLEEGRVVIFAAGTGNPFFTTDTAAALRGAEIGAQIVL
                     KATKVDGVYTADPKKDPQAQRYHRISFDEAIGRNLQVLDSTAFALCRDQKLPINVFSI
                     FKPGALKRVVMGEDEGTLVHS"
     gene            complement(7154..8050)
                     /gene="tsf"
                     /locus_tag="P5537_12210"
     CDS             complement(7154..8050)
                     /gene="tsf"
                     /locus_tag="P5537_12210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HRV78846.1"
                     /translation="MAEITASMVKELREKTDAPMMECKKALAEAAGDMGKAEEILRVK
                     LGNKASKAAARIAAEGVVGIDISADGKLGSIIEVNCETDFVAKNDDFLALVQNCAGLV
                     SAKNPADVAALSALPLGEGTVESTRTALVGKIGENMSIRRFARVEAKGKLFSYIHGGA
                     KIGVLLDVVGGDEQLGKDIAMHIAASKPKALDASGVSQDLIDAERRIAIEKARADNKP
                     EAMLEKIADGTVQKFLKEVTLLAQVFVKAEDGKQTIEQLLKAKGASVASFTLYIVGEG
                     IEKKVTDFAAEVAEQAAAAAKK"
     gene            complement(8216..8971)
                     /gene="rpsB"
                     /locus_tag="P5537_12215"
     CDS             complement(8216..8971)
                     /gene="rpsB"
                     /locus_tag="P5537_12215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HRV78847.1"
                     /translation="MSVTMRQMLEAGVHFGHQTRFWNPRMAPYIFGQRNKIHIVNLEK
                     TMAKYNEAMEFVRKLAANRGNIMFVSTKRQAREIIAEEAQRAGMPYVDERWLGGMLTN
                     FKTVKQSIKRLKEVEAMMEDGSIERLSKREALTVRRELEKLQKSIGGIKDMGGLPDAL
                     FVIDVGYHKIAITEAQKLGIPVVAVVDTNHSPEGVDYLIPGNDDSSRAIRLYARGVAD
                     AVLQGRSQVLQEIVDAGGDEFVEVEEEGSQEQA"
     gene            9366..10196
                     /gene="map"
                     /locus_tag="P5537_12220"
     CDS             9366..10196
                     /gene="map"
                     /locus_tag="P5537_12220"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HRV78848.1"
                     /translation="MSIVIKTPEEIEKMRVACRLAAEVLDYIEPFVVPGVTTGELDRL
                     CHDYMVNVQDTIPAPLDYAPPGYTPYPKSICTSVNHQVCHGVPGEKALKKGDIVNLDI
                     TVIKDGFHGDTSRMFLVGGESACSIVARRLTRITYECMWLGIAAVRPGGRLGDIGAAI
                     QKHAEGNGFSVVREFCGHGIGRKFHEEPQVLHYGKAGTGPTLEPGMIFTIEPMINAGK
                     AAISELPDGWTIVTKDRSLSAQWEHTVVITDTGVEVLTLSAKCPPPPELVAARFATTG
                     "
     gene            10220..12796
                     /locus_tag="P5537_12225"
     CDS             10220..12796
                     /locus_tag="P5537_12225"
                     /EC_number="2.7.7.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008773 - [protein-PII]
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006807 - nitrogen compound metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="[protein-PII] uridylyltransferase"
                     /protein_id="HRV78849.1"
                     /translation="MNDALTEELHTLAATARQRLVEGTAQLREAYQARPQTSSLLKGR
                     ARLVDQELVRLWAACAMPASAALVAVGGYGRGELFPASDVDLLVLLSAPPDEALRARL
                     SALVGALWDCGLEVGHAVRTVDECMVAAADDITVQTNLLEARLLAGNAALFAELNARY
                     RDALDVRAFYKAKLLEQEQRYARFNDTPYALEPNCKESPGGLRDLQMLGWIARAAGLG
                     HNWRDLARHRLITGGEAGELRAIERFLQHIRIRLHHLTGRAEDRLLFDHQEKLARILG
                     IEATPTRRASEVLMQRYYVTAKMVMQLNTVLLQNYGSVIFPDRGAAIVVNPRFQVVRE
                     LLDIRDEDVFERHPSALLECFLLLQQRSELKGMTARTLRALWIHRNQVNAAFRADPAH
                     RALFLQILQQRRGIVRVFRKMNEYGILSRYIPAWRRIVGQMQHDLFHVYTVDQHILMV
                     LRNVRRFTMGEHAHEYPLMTRLIMAFERPWLLYVAALFHDIAKGRGGDHSTLGMADAR
                     EFCVQHGMDADDSALVVWLVEQHLTMSRVAQKEDTSDPEIIQRFADVVRDERRLVALY
                     LLTHADIRGTSPKVWNGWKGKLLEDLFFATQRLLRGATAKEALGLDGRLEDARRQLRF
                     HGLRPGVEDALWARLDPVYFMRHSAEEIAWHTRVLYYRTDSEEPVVKARVAEDEDGVQ
                     VMVFTRDQKDLFVRLTGFFGRMGFTIVDAKVHTTRHGYALDSFMLQDPGEQAAYRDIV
                     ILIEHELSARLQKPGVPERPSRGRMSRQVKHFPISPEVSIRPDEAGRHHVLSLTAADR
                     PGLLYDVAAVLAEHGIRLHTAKIATLGERVEDTFLLTGNALNQDAQVLRIERELLERL
                     QV"
BASE COUNT         2110 a         4464 c         4282 g         2078 t
ORIGIN      
        1 gaaattgacc tggtcgtcct cggcgatcgg ccagccgagg cggatgcctg cgccggtcga
       61 cacggtcttg tacggcgaca ccgagtcgag ctcgtcggcg tcataggtgc ggtggtagag
      121 atcccagccc aggctgacac cgtcgaccgt gtagtacggg ttggtgaagg acagcgcgag
      181 cgtgcggctg gactcgctgg tgttgaggcc gagcgtcagt gcgttgccgc tgccgaacag
      241 gttttgctgc gcgatcgagg ccgacagcac gatgttctcc gagctggaaa aacccgcacc
      301 cagcatcagg ttgccggtgg gacgctcctt gacggaaaag ttgacgtcga cctggtcggt
      361 ggtccccggg accgccggcg tttcgacggt cacctcgtcg aagaagccaa ggcggtcaat
      421 gcgcgtgcgc gaacgattga tcgcttccgc gtcgtaccag ccgccctcca tctggcgcat
      481 ctcgcgacgc acgacctcgt cgcgcgtctt ggtgttgcca ccgacgttga tgcggcgcac
      541 atacaccctt cgacccggat cgacaaagac cgtgaaggcg acctcgcgct tgaccttgtc
      601 gacttcgggg gcggcattga cgttggcgaa ggcgtaaccc tcgttgccga ggcggtcggt
      661 gatcgccttg gtggtctcgg tgagacgctc gcgcgagaag gtctcgccgg gacggatctt
      721 cgtcagcgcc tgatattcgg attcgggcag gatgagatca ccggtgaagc gcacgccgct
      781 caccgtgtac ttctcgccct cggtgatgtt caccgtgatg tagatgtcct gcttgtcagg
      841 cgtgatcgac acctgcgtgg agtcgatgtt gaagtcgaga tagccctggt tcaggtagaa
      901 ggagcgcagg gtctcgaggt ccgccgacaa cttctggcgg gagtactggt cgttcttggt
      961 gtaccaggtc agccagccgg gcgtggtcaa ctgcatctcg tcgagaaggt cgtcctcctc
     1021 gaaggtcttc gctcccacga tccggatctg gcggatcttg gccacgccgc cctcgtcgac
     1081 cttgaagttg atgccgacgc ggttgcgctc gagcggggtg acggtggtgg tgaccgtggc
     1141 ggcgtacttg ccgcgcgaca ggtactggcg cttgagctcc tgctccgcgc gttcgagcag
     1201 cgaacgatcg aagatgcgag actcggcgag gccgacctcg cgcagcccct tctcgagcgc
     1261 atccttgtcg aattccttga cgccgtcgaa ggtgatgtcg gcgatcgccg cgcgctcgtc
     1321 caccaccacg acgatgacct cgccttcggt ctcgatgcgc acatcgctga agaagccggt
     1381 ggcgaacagc gcgcggatgg cgtcggcggc ctgcgcctcg gtgaaggtct cgccgacgcg
     1441 gaccggcagg tagttgaaga cggtgcccgc ctccgtgcgc tggatgccct cgacgcggat
     1501 gtccttgacc acgaagggat cgaaggcgag ggccggcgac gcggcaaaaa gggccaccag
     1561 gagcccgggc aggagcttgc gattcatgcg ggagttcagc cggaaatgag acggttcagg
     1621 tcgttgtaga aggcgaatgc catcatcatc accaggaggg cgaggccgat ctgctgaccg
     1681 acctccatga cgcgctccgg gatcggaccg cccttgatga tttcgatcgt atagtacaac
     1741 aagtgccccc catccagaac cgggatgggc agcaggttca ggacccccag gctgatgctg
     1801 atgagggcca cgaacttgag gtaatgcgtc catcccagct gggcggtctg gcccgcgtaa
     1861 tccgcgatgg tgaccggtcc cgagaggttc ttccacgaca cctcgccggt gagcatgcgg
     1921 ccgatcatct tgaggctgag cacactcgtc tcccaggtct gctggaccgc gcgcgacagc
     1981 ccttcgagca cgccgtagcg cacttcgccg aacatcgcga taccgcccgc tgcggcctcg
     2041 gccacgccga cgccgatgcg gccgatctgc gccccaccct cctcggccgc ctccggggtg
     2101 atcaccagct tcacggcctc gccgccacgc tcgacctcga agtcgagcgc ccgccccggc
     2161 gcctcgcgca ccagtcgcac cagatcgctc caggccacga ccggcgtgcc cgcgatcgcc
     2221 agcacgcgat ccccgtcctg cagtcccgcc cgctcggccg cgctcccatc cgcgacccgg
     2281 ccgatcaccg ccgggatcgc gggacgccac gggcgcaggc cgaggcgcgc gatgaggtcg
     2341 gtgccaccct cgtcgatcgc caccccggag agatccaggc ggcggaacgc ctcgacgtcc
     2401 tcgagggtgc gcacgcgcag catcacctcg cggctgtcga gcgcgtggcg cagcagtacc
     2461 cagcgcaggt cctgccagct gcgcaccggc tcctcatcca ccgccaccac gaggtcaccc
     2521 tcgcgcacgc ccgccgcctg ggcgatcgcc ggggtgtcgg acagcgtcac gcgcggcttg
     2581 agctcctcgg tacccgcgac gaagagcccc cagtagagtg cgatcgcgag caggaagttg
     2641 gccagcgggc cggcagcgac gatcgcgaag cggcgataca cgctctgtcg gttgaaggcg
     2701 cggtgcagtt cgggcgctgc caccggcgcc tcgcgctcgt cgagcatctt gacgtagccg
     2761 ccgagcggaa acgcggcgag cacccactcg gtgccgtcgc ggcccgcggt gcgccgcagc
     2821 aacggctttc cgaagccgat cgagaagcgc agcaccttga ccccgcacca gcgcgccacc
     2881 aggtaatgac cgagctcgtg gacgaggatg agcaggccga gcgcaagggc gaacggaatc
     2941 aggtagtcga agagggtcat cggttttttc gaagtcggga gatctcgtcc cgcgcgagtt
     3001 cgcgggcgtg cgcgtcggcg gacaacaccg cctccagcga atcgaccgcg cccggccggc
     3061 tgcgttccag actcgccgcg atcaccgcgg cgatgtcgag gaagccgatg cgatgatcga
     3121 ggaaggcagc gacggcctcc tcgttggcgg cattgagcac tgcgggggct gtcccgcctg
     3181 cgcgcagcgc atcgaaggcc agtttcaggc aggggaaacg gccgaagtcc ggacgctcga
     3241 aatcgaggcg ggcgatctcg aacaggtcga gcggacgcac gccggcatcg atgcgctcgg
     3301 gccaggccat ggcgttggcg atcggggtgc gcatgtcggg gttgccgagc tgggcgatca
     3361 ccgagccgtc ggcatagtcg accatcgagt ggatcacgct ctgcggatgc acgaccacct
     3421 cgatcatctc cgccggcgcg ccgaacagcc agtgcgcctc gatgacctcg aggcccttgt
     3481 tcatcatggt ggcggagtct accgagatct tgcgccccat gacccagttg ggatgggcac
     3541 aggcctgctc gggggtgacg tcggcgagcg cctcgatcgg cgcgctgcgg aaggggccac
     3601 cggaggccgt cagcaacacc ctgcgcaccc cggctctcgc cggctgccgt ccgtagtcgg
     3661 cgggcagagc ctggaagatg gcgttgtgtt cgctgtcgat cggcagtagc accgcaccgc
     3721 tcgcggccac ggcgtcgatc agcagctgcc cggacagcac cagggcctcc ttgttggcga
     3781 gcaggacctt cttgccggcg cgcgccgcgg ccagggtggg gcgcagcccg gcggcaccga
     3841 cgatcgcggc catcaccatg tccaccacct cggcggcggc gacgcgctcg agcgcctctt
     3901 caccgcacag cacctcggtg tcactgcccg ctgcgcgcaa gccggcgcgc aggagctcgg
     3961 ccgcggccgc gtcgcccaac accgcaaagc gcggcgagaa gcgcaggcac tgatcgagca
     4021 gcttgtcgcc ctggcgctgc gcgctgagcg cgaacacctc gaagcggtcg ggatggcggg
     4081 cgacgacatc gagcgtgctt tggccgatcg atccggtcgc gcccaggaca gtgaggcgct
     4141 ggggtgcggg gtcaggcatg gggagaatcc gttacggagg aaacacggcc gcagccgcgg
     4201 aggatcagcg cgcgagccag accgcgccga gcgccacgag cgggagcgtg gacgtgaggc
     4261 tgtcgatgcg gtcgaggatg ccgccgtggc cgggcaggat gctgccgctg tccttgagcc
     4321 cggcctggcg cttgagcagg gactcgaaga gatcgccaac gatgctcact gcagtccatg
     4381 ccaacagcac accggcaatc accgcaacgc caccctgcag ctcggcgcca cgcatcgcca
     4441 gcatgccgaa gccgaacacc agcaccgcga ccgcggcccc ggcagcgccc tcccaggtct
     4501 tgccggggct gatcgagggc gccagcttgt ggcggccgaa tgcacgcccg ctgaagtagg
     4561 cggcaatgtc ggccacccag acgacggcca tcgtgccgag cagcacccag gggcccatgg
     4621 tgcgcaactg catcatcgcc agtgcggtcg gcacgaggac gatgaagccc accagcgagg
     4681 ccagcatcgg gttggacaag gcccacttgc cgcgcagcca cagcggcacg acgaagatcc
     4741 agaacaagcc gctgaagaca tagagcggca ccaaggcccc ggcaccgccg agctggccgc
     4801 tgcccagccc tgcgctccag cccaggagcg cgcatgcggc ggtgaaggcg accgcggttg
     4861 acacgcgcag cccgtgatcg aagcgggcta gcgcccccca ctcccacgca gcggcgccgc
     4921 acaaggcggc gcagaccacc agccagagcg aagcgggcag caggaacacc gcaccgagca
     4981 gaccaaacag cagcacgatg gcggtcagga cgcgatcctt gagcatggcg cccctactcc
     5041 ccggcgtctg ccttgagttg ctcgctggtg cgcccgaagc gtcgctcccg cgcctgatag
     5101 gagccaatgg ccttgcccag cgcctcgtcg tcgaagtctg gccaaagcac gtcggtgaaa
     5161 tagagctcgg tataggcgag ctgccagagc aggaagttgc tgatgcgctt ctcgccaccg
     5221 gtgcggatga agaggtcggg ctcgggcgca aagctcatcg acagctcggc cgcgagctcc
     5281 tcctcggtga atcgctccag gcgtccaggc tcgcgcgcca tcaggcgcga catggcgtcg
     5341 aggatgtccc agcgcccgcc gtagtttgcc gccacggtga agttgagccc gccgttgcct
     5401 gcagtgagtg cctcggcctc gcggatcatg tccaccaggc ggccatcgaa gcgggagaga
     5461 tcgccgatca cgcggaaacg catgtcgttg tcgtgcatgc ggcggatctc cttttgcagc
     5521 gacttcagga agagctgcat caggaacgag acttcgtcct gcggccggcg ccagttctcg
     5581 gaactgaacg caaacacggt gaggtattcc accccacgat cgacgcagcc gcgcaccgtg
     5641 gcgcgcagcg cctccacacc ccgcgcatga ccggcgacac gcggcagcat gcgcttgcgc
     5701 gcccagcgcc cattgccgtc catgatcacg gcgatgtgct gcggcacctg cgagacgtcg
     5761 ggaatgtcgc gggtggaact cctgaacagt cctccgatca tgctccgcct cctgtcgtgc
     5821 ccgttgacga tacagccgat ccgcgcacgc ggatcagatc tgcatcagtt cctgctcttt
     5881 ctgggcgagc agcttgtcga tctcggccac atagcgatcg gtgagcttct ggatctcgtc
     5941 ctcgccacga cgctcgtcgt cctcggagat ctccttgtcc ttgaccgcgt ccttgagctg
     6001 ctgattggcg tcgcggcgca ggttgcggat cgccaccttg gcggtctcgc cctcgtggcg
     6061 caccaccttg gtgaggtcgc ggcggcgctc ctcggtcagc gcgggcatcg gcacccgcag
     6121 cagttcgccc atgttggcgg ggttgaggcc gaggtcgctg tcgcggatcg cgcgctcgac
     6181 cttgccgagc atcggcttct cccaggtctg cacgccgatg gtacgggcgt cgatcagcgt
     6241 gatgttggcg acctggttca ccggcaccat cgagccgtag tactcaacca tgacgtggtc
     6301 gagcaggccg gtgtgggcgc ggccggtacg caccttggcg aggtcggtct tgagcgcctc
     6361 gaccgacttc tgcatcttct gctcgatgtt cttcttgagt tcggaaatca tgcaagccct
     6421 ctccggaggt caggaatgga ccagcgtgcc ttcatcctca cccatcacca cgcgcttgag
     6481 cgcgccgggc ttgaagatcg agaacacgtt gatcgggagc ttctggtcgc ggcacagcgc
     6541 gaacgcggtc gagtcgagca cctggaggtt gcgcccgatc gcctcgtcga agctgatgcg
     6601 atggtagcgc tgcgcctgcg gatccttctt cggatcggca gtatagacgc cgtccacctt
     6661 cgtcgccttg agcacgatct gcgcgccgat ctcggcgcca cgcagtgcgg cggcggtgtc
     6721 ggtggtgaag aaggggttgc cggtgccggc ggcgaagatg accacgcggc cttcctcgag
     6781 gtgacggatc gcgcgcccgc ggatgtaggg ctcgaccacc tggtcgatgc gcagcgccga
     6841 ctgcacgcgc gcctcgaggt ccatccggcg catcgcgtcg gcgagcgcca tcgcgttcat
     6901 caccgtggcc agcatgccca tgtagtcggc ggtggcgcgg tccatgccgg aggccgcgcc
     6961 cttcatgccg cggaagatgt tgccgccgcc gatcaccaca ccgacctgga cgccgagacg
     7021 ggtgatctcg gcaacctcgg agacgatgcg gctgacgacc tcctcgttga tgccgtaggc
     7081 gtcgtcgccc atcagggctt cgccggagag cttgagcagg atgcgcttgt aggcggcgga
     7141 cacgttcatc tccttacttc ttggcggcag cggcggcctg ctcggcgacc tcggcggcga
     7201 agtcggtgac cttcttctcg atgccttcac cgacgatgta cagcgtgaag ctggcgaccg
     7261 aggcgccctt ggccttgagc agctgctcga tggtctgctt gccgtcctcg gccttcacga
     7321 agacctgggc cagcagggtc acttccttga ggaacttctg cacggtgccg tcggcgatct
     7381 tctccagcat cgcttcgggc ttgttgtcgg cgcgggcctt ctcgatcgcg atgcgacgct
     7441 cggcgtcgat caggtcctgc gacacgcccg aagcgtcgag cgccttcggc ttggacgcgg
     7501 cgatgtgcat cgcgatgtcc ttgccgagct gctcgtcgcc accgaccacg tccagcagca
     7561 cgccgatctt ggcgccgccg tggatgtacg agaacagctt gcccttggct tcgacgcggg
     7621 cgaagcggcg gatcgacatg ttctcgccga tcttgccgac cagagcggtg cgggtcgact
     7681 cgacggtgcc ctcgcccagc ggcagcgccg acagggcggc gacgtcggcc gggttcttgg
     7741 cggagacgag gccggcgcag ttctgcacca gcgccaggaa gtcgtcgttc ttggcgacga
     7801 agtcggtctc gcagttgacc tcgatgatcg agccgagctt gccgtcggcg gagatgtcga
     7861 tgccgaccac gccttcggcg gcgatgcggg ccgcggcctt ggaggccttg ttgccgagct
     7921 tgacgcgcag gatctcttcg gccttgccca tgtcgccagc agcttcggcc agcgccttct
     7981 tgcactccat catcggcgcg tcggtcttct cgcgcagttc cttgaccatg cttgcggtga
     8041 tttccgccat gctagctcct gaataggttc ggtttgacgt tcgaaacgcg gatgccgcgc
     8101 cgcgcaccgg agggccatcg gcgcgacatc atgaattgtg cggggcgcac attgcgggat
     8161 tcgcaggcgc cacccggatt gcaaaagggg ccccgcgggc ccccttcgct gaggatcagg
     8221 cctgttcctg cgagccttct tcctcgacct cgacgaactc gtcgccgccg gcgtcgacga
     8281 tctcctgcag cacctggctg cggccctgca gcacggcatc ggccacgcca cgggcgtaga
     8341 ggcggatcgc gcgcgaggag tcgtcgttac ccgggatcag gtagtccacg ccctcgggcg
     8401 agtggttggt gtcgaccacg gccacgaccg gaatgccgag cttctgggct tcggtgatgg
     8461 cgatcttgtg atagccgacg tcgatgacga acagcgcgtc gggcaggccg cccatgtcct
     8521 tgatgccgcc gatcgacttc tgcagcttct cgagctcgcg acgcacggtc agcgcctcgc
     8581 gcttggacag gcgctcgatc gagccgtctt ccatcatcgc ctcgacttcc ttgaggcgct
     8641 tgatcgactg cttgaccgtc ttgaagttgg tcagcatgcc gccgagccag cgctcgtcga
     8701 catagggcat gccggcgcgc tgggcttcct cggcgatgat ctcgcgcgcc tggcgcttgg
     8761 tgctgacgaa catgatgttg ccgcggttcg cggcgagctt gcgcacgaac tccatggcct
     8821 cgttgtactt cgccatcgtc ttctcgaggt tgacgatgtg gatcttgttg cgctggccga
     8881 agatgtaggg ggccatgcgc ggattccaga agcgggtctg gtggccgaag tggacgccgg
     8941 cttccagcat ctgacgcatc gtgacggaca tgtgttgctc caaactgtac aagggttgaa
     9001 cctccgcccc gcggacgggc ggccggaaaa ccggaccgac ccgttgccca ccgggattcg
     9061 cgcgaccccg cccggacgat gccgggacgc tggaggtcgg gcgagccccc ggaaggaccc
     9121 tgtgccgcaa ggcgtgcgga ttttgcctgc acctgcagac aagcccgcga tcttatcacg
     9181 cgatccgcat cgcgctcaag gttgcagcgg agcgaagcag cgacagggcc aggccgggaa
     9241 ggtgcgggcc acggcgatgg cgaaggcatc gcgtcgcctc cctgtggtgc gcatcccggg
     9301 tttgctgcag cgcgacgctt gcgatagcct tcccgcttta ccgccccgac gcagaacaca
     9361 caaaaatgag cattgtcatc aagaccccgg aagagatcga gaagatgcgc gtggcctgcc
     9421 ggctcgccgc cgaagtgctc gactacatcg agcccttcgt cgtccccggc gtcaccaccg
     9481 gcgaactcga ccgcctgtgc cacgactaca tggtgaacgt gcaggacacc attcccgccc
     9541 cgctcgacta tgcgccgccc ggctacacgc cctaccccaa gtcgatctgc acctcggtga
     9601 accatcaggt atgccacggc gtgcccggcg agaaggcgct caagaaaggc gacatcgtca
     9661 acctcgacat caccgtgatc aaggacggct tccacggcga caccagccgc atgttcctgg
     9721 tcggcggcga gtccgcctgc agcatcgtcg cccggcgcct gacgcgcatc acctacgagt
     9781 gcatgtggct gggcatcgcc gcggtccggc ccggcggccg cctcggcgac atcggcgcgg
     9841 cgatccagaa gcacgccgaa ggcaacggct tctcggtggt gcgcgagttc tgcggccacg
     9901 gcatcgggcg caagttccac gaggaaccgc aggtgctgca ctacggcaag gccggcaccg
     9961 gccccacgct cgagccgggc atgatcttca ccatcgagcc gatgatcaac gccggcaagg
    10021 cggcgatctc cgagctgccc gacggctgga ccatcgtcac caaagaccgc agcctgtcgg
    10081 cgcagtggga acacacggtg gtgatcaccg acaccggggt cgaggtgctc accctctccg
    10141 ccaagtgccc gccgccgccc gagctcgtcg ccgcccgctt cgccacgacg ggctgaggaa
    10201 acccgaccca ggcccgcgca tgaacgacgc cctcaccgaa gaactgcaca cccttgccgc
    10261 cacggctcgc caacgcctcg tcgagggcac ggcgcagctg cgcgaggcct atcaggcgcg
    10321 gccgcagacc tccagcctgc tcaagggccg cgcccgcctg gtcgatcagg aactcgtccg
    10381 cctgtgggcg gcgtgtgcga tgcccgcctc cgcggcgctg gtggcggtgg gcggctatgg
    10441 ccgcggggag ctcttcccgg cctcggacgt cgatctgctc gtgctgctct ccgctccgcc
    10501 cgacgaggcg ctgagggcgc gcctgtcggc gctcgtcggc gcgctgtggg attgcggact
    10561 cgaggtcggg cacgcggtac gcacggtgga cgagtgcatg gtcgccgccg ccgacgacat
    10621 caccgtgcag accaacctgc tcgaggcgcg cctgctcgcc ggcaacgcgg cactgttcgc
    10681 cgagctgaat gcgcgctacc gcgatgcgct cgacgtgcgc gccttctaca aggcaaagct
    10741 gctggagcag gaacagcgct acgcccgctt caatgacacg ccctatgccc tcgagcccaa
    10801 ctgcaaggag agccccggcg ggctgcgcga cctgcagatg ctgggctgga tcgcgcgcgc
    10861 ggccgggctc ggccacaact ggcgcgacct cgcccgccac cgcctgatca ccggcggcga
    10921 ggccggcgaa ctgcgcgcga tcgagcgctt cctgcagcac atccgcatcc gcctgcatca
    10981 tctgaccggg cgcgccgagg accgcctgct cttcgaccac caggaaaagc tcgcccgcat
    11041 cctcggcatc gaggccacgc ccacccggcg cgcctccgag gtactgatgc agcgctacta
    11101 cgtcaccgcc aagatggtga tgcagttgaa caccgtgctg ctgcagaact acggcagcgt
    11161 gatcttcccc gaccgcggcg ccgcgatcgt ggtgaatccg cgcttccagg tcgtgcgcga
    11221 gctgctcgac atccgcgacg aggacgtctt cgagcgccac ccttccgccc tgctcgagtg
    11281 cttcctgctg ctgcagcagc gctccgagct caagggcatg accgcgcgca cgctgcgtgc
    11341 cctctggatc caccgcaacc aggtcaacgc cgccttccgc gccgaccccg cgcaccgcgc
    11401 gctcttcctg cagatcctgc agcagcgccg cggcatcgtg cgggtgttcc gcaagatgaa
    11461 cgaatacggc atcctgtcgc gctacattcc ggcgtggcgg cgcatcgtcg gccagatgca
    11521 gcacgacctc ttccacgtct atacggtcga ccagcacatc ctgatggtgc tgcgcaacgt
    11581 gcgccgcttc acgatgggcg agcacgccca tgaatacccg ctgatgacgc gcctgatcat
    11641 ggccttcgag cgcccctggc tgctctacgt cgcggcgctc ttccacgaca tcgccaaggg
    11701 ccgcggcggc gaccactcca cgctgggcat ggcggatgcg cgcgagttct gcgtgcagca
    11761 cggcatggac gcggacgaca gcgcgctggt cgtctggctg gtcgagcagc acctcaccat
    11821 gtcgcgcgtc gcgcagaagg aggacacctc cgaccccgag atcatccagc gcttcgccga
    11881 cgtcgtgcgc gacgagcgtc gcctggtcgc gctctacctg ctcacccacg ccgacatccg
    11941 cggcaccagc cccaaggtct ggaacggctg gaagggcaag ctgctcgagg atctgttctt
    12001 cgccacccag cgcctgctgc gcggtgccac cgccaaggag gcgctcggcc tcgacggccg
    12061 cctcgaggat gcccgccgcc agctgcgctt ccacggcctg cgcccgggcg tggaggacgc
    12121 gctgtgggcc cggctcgacc cggtgtattt catgcggcat tccgccgagg agatcgcctg
    12181 gcacacgcgg gtgctgtact accgcaccga ctcggaagag ccggtagtga aggcgcgcgt
    12241 ggccgaggac gaggacggcg tgcaggtgat ggtgttcacc cgcgaccaga aggacctctt
    12301 cgtgcgtctc accggcttct tcggccgcat gggcttcacc atcgtcgacg ccaaggtgca
    12361 caccacccgc cacggctacg cgctcgacag cttcatgctg caggatccgg gcgaacaggc
    12421 cgcctatcgc gacatcgtga tcctgatcga gcacgagctc agcgcccgcc tgcagaagcc
    12481 cggcgtcccc gagcgcccca gccgcggcag aatgtcgagg caggtgaagc acttcccgat
    12541 cagccccgag gtcagcatcc gccccgacga ggccggccga catcatgtgc tgtcgctcac
    12601 cgccgccgac cgccccggac tgctctacga cgtcgccgcg gtgctcgccg agcacggcat
    12661 ccgcctgcac accgccaaga tcgccaccct gggcgagcgc gtcgaggaca ccttcctgct
    12721 caccggcaac gcgctgaacc aggacgcgca ggtgctcagg atcgagcgcg agctgctcga
    12781 gcggctgcag gtctagggcg catgggggcg ccggcgcggg ccggctcggg ccggccattc
    12841 gcgcctgccg gcgctcctac atgaacccac ggggcgggga catgaaccca cggggcgggg
    12901 acatgaaccc acggggcggg gacatgaacc cgcg
//
LOCUS       DAOTIN010000087        12733 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_5890_length_12733_cov_8.520429, whole genome shotgun sequence.
ACCESSION   DAOTIN010000087 DAOTIN010000000
VERSION     DAOTIN010000087.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 12733)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 12733)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12733
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5890_length_12733_cov_8.520429"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(28..1038)
                     /locus_tag="P5537_12230"
     CDS             complement(28..1038)
                     /locus_tag="P5537_12230"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005536 - glucose binding [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucokinase"
                     /protein_id="HRV78850.1"
                     /translation="MNRASAPYPRLVADIGGTNARFALVEAPGAAPTQLRSLRCAEHA
                     GPEAALRAWLEATRTRLPDYAAFGIATPIDGDAVAMTNHPWRFSIGTLRAALGLRRLT
                     VVNDFTALALSLPALGDDDLVRVGGGEARADSARALIGAGTGLGVSGLLPAPGGWVPL
                     QGEGGHVTLPATNAREAAVVAWLGARHGHVSAERVLSGPGLVALHEALCALDEVPHVE
                     RTAAEITEHALAGGCHHCVEALELFCALLGTVAGDLALTLGARGGLYIGGGIVPRLGD
                     FFLRSAFRERFVAKGRFRPWLEQIPTWVILAPHAALTGASAALDGAIEVGFTALAEPP
                     PP"
     gene            1461..3170
                     /locus_tag="P5537_12235"
     CDS             1461..3170
                     /locus_tag="P5537_12235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HRV78851.1"
                     /translation="MSLTTPIPAPATAASTPWWKSAVAYQLYPRSFMDSDGDGIGDLR
                     GILTRLDYLQWLGVDVIWICPIFDSPNDDNGYDIRDYRKILPTFGTMEDFDRLLAEVH
                     RRGMKLILDLVLNHTSDEHPWFLESRASTDNPKRDWYLWREGRDGHPPNNWESIFRGP
                     AWTRDPSTGQYYLHLFTRRQPDLDWTNAGMRAAFYEIVHWWLDKGIDGFRLDAVSHIR
                     KMPGLPDLPNPHGLPWVPSFPMHMNVDGVLDHIDELCRETFRRYDVMTVGEANGVGPH
                     QAIDWVGTDRRRLDMIFQFEHLALWSRAPGAPLDVVALKKVLSRWQHALHGKGWNALF
                     LENHDIPRVVSKWGDTGALWRESATALATMYFLMEGTPFIYQGQEIGMTNGVFEHIED
                     FDDVLAKNDYAQRRLAGEDERAIIADLVLTGRDPARTPMQWDDGPQAGFTRGRPWLAV
                     NPNHRRINVAQQRHDPASVLNHYRRLIALRKAEPALLHGDYRLLMKDDAQIFAYQRRL
                     DGERIAVIVNLSQRQARFDHPGVVLRHERLLLANRAVEPHPATHALDLAPYEARVYRV
                     GKM"
     assembly_gap    3369..3468
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(3493..4317)
                     /locus_tag="P5537_12240"
     CDS             complement(3493..4317)
                     /locus_tag="P5537_12240"
                     /EC_number="2.3.1.286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Sir2 family NAD-dependent protein deacetylase"
                     /protein_id="HRV78852.1"
                     /translation="MSLPAAPIARIARWIHEADGLIVAAGAGMGVDSGLPDFRGSAGF
                     WRAYPALGRARLQFEEIANPAAFARDPALAWGFYGHRLALYRRTVPHRGFALLREIAA
                     GLSAGAFVFTSNVDGQFQKAGFAQERIMEVHGSIHHLQCQRACRGEVWSAEGFEPRVD
                     EEACRLLGEPPRCPHCGDIARPNILMFGDWGWIARRTEVQEAALATWLERVRRPVVIE
                     LGAGEKVPTVRRFAESIGDRLVRINPQAEPNLPAGAVHLRCGALEGIAAVHRALAE"
     gene            4585..5067
                     /locus_tag="P5537_12245"
     CDS             4585..5067
                     /locus_tag="P5537_12245"
                     /inference="COORDINATES: protein motif:HMM:NF015669.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="META domain-containing protein"
                     /protein_id="HRV78853.1"
                     /translation="MNTAKTARSLAVLAVAALLAACSGKGMTPFTKIDGSDPGVLGKM
                     DGSWTVMNTGDTKAEGMTPPAVVVFDTRAKAVSGFDGCNDFKGSYSFDQGLLKAKVSS
                     TRRACTSDMARTISARLGDLFTKGAEVVDTSFMGAHVLMLRNAGGDVRMGSTEVLRKP
                     "
     gene            5067..6107
                     /locus_tag="P5537_12250"
     CDS             5067..6107
                     /locus_tag="P5537_12250"
                     /inference="COORDINATES: protein motif:HMM:NF016087.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper resistance protein NlpE"
                     /protein_id="HRV78854.1"
                     /translation="MRRPRFRFAAAPALACLALTGAAAQATSQGPVADGPYVGTLPCA
                     DCAGIRTSLTLYTMGQGGLPLVYRMTRVYLGTPAGDRGEEYIGPWSRIDAGAGETLRI
                     EPHDDARRSSFRRADVDRLVLLDRSEQPIATRQDLALVRDPGADAARLTVPRTLFRGT
                     LQRDAGKLRFAPCGGGKPFDARDVSAESVITAAVTDAGFDTHGAIYLEAWGERRGGEL
                     QLERLNRAGHDLACPTSALGVAAQGNAPSWRLESDRRAVRFSGEGGEPLNMPPLPLSW
                     HWPVGRPDRAEAVLAGATESATLRLRLFPSICRDASTGTVHGFRAALAVTRAGPPVEY
                     TGCGHLGNEALY"
     gene            complement(6144..7229)
                     /gene="torT"
                     /locus_tag="P5537_12255"
     CDS             complement(6144..7229)
                     /gene="torT"
                     /locus_tag="P5537_12255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004291427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TMAO reductase system periplasmic protein TorT"
                     /protein_id="HRV78855.1"
                     /translation="MRHGLRGFALGALLSCAAALAGAQPAPEWPVQRWEGDHRAADAA
                     AVAAPDIAPPSPTRAWRLCAIYPHLKDSYWLAVNFGMTEEARALGLGLGVREAGGYGQ
                     LARQRERVAACLADAAVDALLIGTVSRGGLNDLLAPQLERRLVLGVVNDIDPQVVRAR
                     IAVPWYQLGWTIGRWLAERHPAGAPAARIAWVPGPVDADWVGFIDRGFRAGIAGSAVR
                     IVAERHGDTGRAIQRRLVEAVLDEQPQLDYLVGNAPMAEAAIAELRRRGRAGSTAIVS
                     SYLTPAVHGGILRGRILAAVTDFPVLQGRLAVRQALRALEGRPIEPYLGPSVELVDKR
                     SLALFPAQWMLPPAGFVPVYEIAPGAR"
     gene            7323..10301
                     /locus_tag="P5537_12260"
     CDS             7323..10301
                     /locus_tag="P5537_12260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002928172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HRV78856.1"
                     /translation="MKPHTGRRFGLRERLLLGLLVAALGTVLVAVVGWVSFQRVVSSQ
                     QAIVRDTLPAADALHEAVRANARLAALAPRLLRADSAAELGQLRAALDVDVPLVRDRL
                     AALRSPHVEAALRDRLQSTGDRLAAALRGMSAAIAERLRLRAARVERIDALRAVIDEL
                     DELAGIHADNATAQLVATLTSLLQPDPVQGPRSLDEREAARERVLDLDIDSLERMHEL
                     NLTVHALGFLVGRLDELDSNARLQAARGEFAEHLALLARRLADIPDPGGREQGRQVHQ
                     LLASALEDEGAFALRARELALRAQVETLQGVVGELTTELDALAGELIHRGGRLLAAAG
                     SAAERSATSGLIAFGVIAAALLLVTLGVTVHALRRHTLGRLRALEEATLALASGRREV
                     AIDTTGDDELASLAVALERFRANAIERDRLAEALRGQQQELENQVLARTAQLREANAA
                     LARETADHARARHAAEQADRAKTAFLGTVSHELRTPLAGILGLLELVEDAGSATERTQ
                     YQAQMRAAAVLLLELLEDMLDFARIEAGGVQLDNMGFSLRDTVNDVFAVQGTRAAVRG
                     LALVAEVDPALPDAVQGDRRKLSQILLNLVGNAIKFSDEGAVTVRVRAGTQPGRLHFA
                     VEDHGIGIEPARQQEVFEPFVQVRDSGRHHAGTGLGLAVCRRLVEAMGGAIELKSAPG
                     KGTTVSFEIALPATTATPAEATAATATTDASAPAPGHRVLVVEDDEVNRMVVERFLDA
                     LGQQAVCAPDIHNALRLLHERPIDLALIDMNLPDGDGRELLARLRALPAHARTPAVLM
                     SAHIPRREVDALLEAGFAAFLSKPFSRQRLRALLAKLLSGGRAEPPAGEGDPGAASAA
                     EAVTAATATAAPEAPQAEDWIDIDFLRAEQEALGEEIVADIVRVFRTQGQPLIDALLA
                     AARAGEQADCARLAHKLRGAAGNVGAGRLAACAGTLEDALKREPSRAAGVEDLAERAG
                     ELGGAWAHTLQALDALRLGA"
     gene            complement(10325..11053)
                     /locus_tag="P5537_12265"
     CDS             complement(10325..11053)
                     /locus_tag="P5537_12265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004291430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV78857.1"
                     /translation="MSPTPDATPTLLVVDDDLVAQARMNAYFSKEGYRVLLAGDGEAF
                     WRQLGQGGVDLVLLDINLPGQDGLSLARELRARDASIGIILVTSRDDDVDKIVGLEVG
                     ADDYVTKPFNPRELLARVKSLLRRSGARPAEVADSLRFAGWVLELSRRRLRDRAGQDV
                     ALTRGEFEVLALLVRHPGEILDRDRLSRAVSGHDWSPQDRSVDVLVRRLRAKLDDPAR
                     ADSLIATIRGEGYRLAVDVESGGS"
     gene            11372..11761
                     /locus_tag="P5537_12270"
     CDS             11372..11761
                     /locus_tag="P5537_12270"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011236038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HRV78858.1"
                     /translation="MTGSNCPFCQLDAARIVFSDDVTLVIRDAFPVSPGHTLIIPRRH
                     VGSFFELTPPERARMFELLTQAKAELDGTLQPDGFNIGINDGAAAGQTVAHLHLHLIP
                     RYRGDTPDPRGGVRWVLPAKAKYWSGQ"
     gene            11758..12405
                     /locus_tag="P5537_12275"
     CDS             11758..12405
                     /locus_tag="P5537_12275"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78859.1"
                     /translation="MSLSTYVDRFRRLNVNVAHGRASPHKICMLLAVLDLARGGALTE
                     NRVEFAPPLLERYALYFNAVRAEGDHPNPYFPFFHLAGRLRGGGESFWHLQPKSGREH
                     VLASMSTARTVWQVTDNIDHARLDAELFDLLQDALAVDTLSAVLAPDMHWALDRHLIA
                     PHSDFRWRVSRALDRRIPDYQVLTELEGKPLFLPREAHMYPKREAIEWRLAMLDT"
     gene            complement(12499..>12733)
                     /locus_tag="P5537_12280"
     CDS             complement(12499..>12733)
                     /locus_tag="P5537_12280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78860.1"
                     /translation="ASFIADWLRRSERALPLAERRQLSALSDGLARQIAGSLSREAGL
                     YTTHEMMEALDPNHDSELARSMMDECARLLAAD"
BASE COUNT         1895 a         4663 c         4377 g         1698 t
ORIGIN      
        1 ggcgctccta catgaaccgt gacgcttcta cggggggggc ggctcggcga gggcggtgaa
       61 gccgacctcg atcgcgccat ccagggccgc ggaggcgccg gtcagggcgg cgtggggggc
      121 gaggatcacc caggtcggga tctgctcgag ccagggacgg aagcggccct tggccacgaa
      181 gcgctcgcgg aaggcggagc gcaggaagaa atcgcccagc cgcggcacga tcccaccacc
      241 gatgtaaagg ccaccgcgcg cgcccagcgt gagcgcgaga tcgcccgcga ccgtgccgag
      301 cagcgcgcag aagagctcca gcgcctcgac gcagtggtgg cagccgcccg ccagcgcgtg
      361 ttcggtgatc tcggccgcgg tgcgctcgac atgcgggacc tcgtcgagtg cgcacaaggc
      421 ctcgtggagc gcgaccaggc ccggccctga gagcacgcgt tcggccgaga cgtggccgtg
      481 gcgtgcgccg agccaggcga cgaccgcggc ttcgcgtgcg ttggtggccg gcagcgtcac
      541 atgtccgccc tcgccctgca gcggcaccca gcctcccggc gccggaagca gccccgacac
      601 gccgagcccg gtgccggcac cgatcagcgc gcgcgcggag tcggcacgcg cctcaccgcc
      661 gccgacgcgg accaggtcgt cgtcgccgag tgcaggcagc gagagtgcga gcgcggtgaa
      721 gtcgttcacc acggtgagtc ggcgcaggcc gagcgcggcg cgcagcgtgc cgatggagaa
      781 gcgccagggg tgattggtca tcgccaccgc atcgccgtcg atcggggtgg cgatgccgaa
      841 ggccgcgtag tcgggcagcc gggtgcgggt ggcctcgagc caggcgcgca acgccgcctc
      901 ggggcccgcg tgctcggcgc agcgcagtga gcgcagctgc gtcggagcag cacccggcgc
      961 ctcgaccagg gcgaagcgcg cgttggtgcc gccgatgtcg gcgacgaggc gagggtaggg
     1021 ggcggaggcg cggttcatgt ggagccaatt ctgccacgcg gcgccacagc ttgaaggcat
     1081 ctgagtcggg tcggtcggcg ggcgaggggc gttctgcgcc ggctgcttcg cgcctgccgg
     1141 cgctcctaca aggggccgtc ggttcgtggg tggcggtgct gttgccgggc gggtgattcg
     1201 cgcctgccgg cgctcctaca ggggcgtcgg gtcgtgggtg ggggggcggc cgaggggctg
     1261 gggtgctgcg tgccggtgga gaaatgcgct cgctgcggcc ccgggagcgc gctgaccgct
     1321 tgccgagcga ggtcgtatgt aggagcgccg gcaggcgcga atgcggcgct ccggcccgtg
     1381 ccatcctcca gctcgtggca cgtcttcatc gaccggccgc aggcctacaa tggaccgcag
     1441 attccccgag cgccacgacc atgtccctga ctacgcccat ccccgcgccc gccaccgctg
     1501 cctcgacccc ctggtggaaa tccgccgtcg cctatcagct ctacccgcgc agcttcatgg
     1561 acagcgacgg agacggtatc ggcgacctgc gcggcatcct cacgcggctc gactacctgc
     1621 aatggctggg cgtcgacgtg atctggatct gcccgatctt cgactcgccc aacgacgaca
     1681 acggctacga catccgcgac taccgcaaga tcctgccgac cttcggcact atggaagact
     1741 tcgatcgcct gctcgccgag gtccaccgcc gcggcatgaa gctgatcctc gacctggtgc
     1801 tcaaccacac cagcgacgag cacccctggt tcctcgagtc gcgggcctcg accgacaacc
     1861 ccaagcgcga ctggtacctc tggcgcgagg gccgcgacgg ccatccgccc aacaactggg
     1921 agagcatctt ccgcggcccc gcgtggaccc gggacccgtc caccggacag tactacctgc
     1981 acctgttcac ccgccgccag cccgacctcg actggaccaa cgccgggatg cgcgcggcgt
     2041 tctacgaaat cgtgcactgg tggctggaca agggcatcga cggtttccgc ctcgatgcgg
     2101 tcagccacat ccgcaagatg cccggcctgc ccgacctgcc caatccgcac ggcctgccct
     2161 gggtgccgtc cttcccgatg cacatgaacg tcgacggcgt gctcgaccac atcgacgagc
     2221 tctgccgcga gaccttccgc cgctacgacg tgatgaccgt gggcgaggcc aacggggtcg
     2281 gcccgcatca ggcgatcgac tgggtgggca ccgaccgccg tcggctcgac atgatcttcc
     2341 agttcgagca cctcgcgctg tggtcgcgcg cgccgggcgc acccctcgac gtggtcgcgc
     2401 tcaagaaggt gctgtcacgc tggcaacatg cactgcacgg caagggctgg aacgcgctct
     2461 tcctcgagaa ccacgacatc ccgcgcgtcg tctccaagtg gggcgacacc ggggcgctgt
     2521 ggcgcgagag cgcgaccgcg ctggcgacca tgtacttcct gatggagggc acgcccttca
     2581 tctaccaggg ccaggagatc ggcatgacca acggcgtctt cgagcacatc gaggacttcg
     2641 acgacgtgct ggccaagaac gactacgccc agcgccgcct ggctggcgag gacgagcgcg
     2701 cgatcatcgc cgacctcgta ctcaccggcc gcgacccggc gcgcacgccg atgcagtggg
     2761 acgacggccc gcaggccggc ttcacccgcg ggcggccttg gctggcggtc aatcccaacc
     2821 accgtcgcat caacgtcgcc cagcagcgcc acgacccggc ctcggtgctc aaccactacc
     2881 gccgcctgat cgcgctgcgc aaggccgaac cggcgctgct tcacggcgac taccgcctgc
     2941 tgatgaagga cgacgcgcag atcttcgcct accagcgtcg gctcgacggc gagcgcatcg
     3001 cggtgatcgt caacctgagt cagcgccagg cgcgcttcga tcaccccggc gtggtgcttc
     3061 gccacgagcg cctgctgctc gccaaccgcg cggtcgagcc gcaccccgcg acacacgcgc
     3121 tcgacctcgc gccctacgag gcacgcgtat accgcgttgg gaaaatgtag gagcaccggc
     3181 aggcgcgaat tgggcggtgg cacgatcgac gtgcatcgag atcctcgacg ccgcattcgc
     3241 gcctgccggc gctcctacat gaaaccggcg caggttcggg ccggaaaccg gcgatcggcc
     3301 atcggcgcgc gttaatctcg gccgcggcgc ctacgcacgc acctgtagga gcgccggcag
     3361 gcgcgaatnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnag gcgcgaatgc
     3481 agcgggtcag cactactcgg ccaaggctct gtgaacggcg gcgatgcctt cgagcgcgcc
     3541 gcagcgcagg tggacggcgc ccgcggggag gttcggttcg gcctgtgggt taatgcgcac
     3601 cagccgatcg ccgatcgact cggcgaagcg gcgcaccgtg ggcactttct cgccggcgcc
     3661 gagttcgatc accaccggtc ggcgcacgcg ctccagccag gtcgcgagcg ccgcctcctg
     3721 cacctcggtg cgccgcgcaa tccaccccca gtcgccgaac atcaggatgt tgggccgcgc
     3781 gatgtcgccg caatgcgggc agcgcggcgg ctcgccgagc agcctgcagg cctcctcgtc
     3841 cacccgcggc tcgaagcctt ccgccgacca cacctcgcca cggcacgcac gctggcactg
     3901 cagatggtgg atggagccgt gcacctccat gatccgctcc tgcgcaaacc ccgccttctg
     3961 gaactgccca tcgacgttcg acgtgaagac gaaggcgccg gcgctcagtc ccgccgcgat
     4021 ctcgcgcagc agcgcgaaac cccgatgcgg cacggtgcgc cggtacagcg ccaggcgatg
     4081 cccgtagaac ccccaggcga gcgcgggatc gcgcgcgaaa gccgccggat tcgcgatctc
     4141 ctcgaactgc aggcgggcgc gcccgagcgc cgggtaggcc cgccagaagc ccgcgctgcc
     4201 gcgaaagtcc ggcagccccg agtccacgcc catgcccgcc ccggcagcga cgatcaggcc
     4261 gtcggcctcg tggatccagc gggcgatgcg ggcaatcggg gcggcaggca ggctcatcgg
     4321 ggcgggcaga gaggacagcg gaaaaaacac ccccgcaacg cgcgcgtcag gggaagaccg
     4381 gcctgcagcc agttgctgcg gcacgcgtcg tggcgattct gcccggatct gcgccccgtc
     4441 ccccacggaa agatgaactt ttccggacag atcctgctgg attacctgta ttgggcacgt
     4501 gccccccggc atcgaccgat gccaggggaa ttgttcggcc gcgccagggt cacccatcca
     4561 tcaccaaacg gagaaaccgc aatcatgaac accgccaaaa ctgcccgttc cctcgccgtc
     4621 ctcgccgtcg cggccctgct cgcagcctgc tcgggcaagg gcatgacgcc attcaccaag
     4681 atcgacggca gcgaccccgg cgtgctcggg aagatggacg gcagctggac cgtgatgaac
     4741 accggcgaca ccaaggccga gggcatgacc ccgcccgcgg tcgtggtctt cgatacgcgc
     4801 gccaaggcgg tctccggctt cgacggctgc aacgacttca agggctccta cagcttcgac
     4861 caggggctgc tgaaggcgaa ggtttccagc acgcgtcgtg cctgcaccag cgacatggcg
     4921 cgcacgatca gcgcccgcct cggcgacctg ttcaccaagg gagccgaagt ggtcgacacc
     4981 agcttcatgg gcgcccatgt gctgatgctc aggaacgccg gcggcgacgt gcgcatgggc
     5041 tcgaccgaag tgctgcgcaa accctgatgc gcagaccgcg ctttcggttc gcggcggcgc
     5101 ctgcactcgc ctgcctggcg ttgacagggg ccgccgcgca agccacctcg caggggccgg
     5161 tggcggacgg cccctacgtg ggcacgctgc cgtgcgccga ttgcgccggc atccgcacca
     5221 gcctgacctt gtacacgatg gggcagggcg gcttgccgct ggtgtatcgg atgacgcgcg
     5281 tctatctcgg cacccccgcc ggggatcgcg gcgaggagta catcggcccc tggagccgca
     5341 tcgacgccgg cgcgggggag accctgcgca tcgagcccca cgacgacgcc cggcggtcga
     5401 gcttccggcg cgccgacgtc gaccgcctgg tgctgctcga ccgcagcgag cagcccatcg
     5461 cgacgcggca ggaccttgcc ctcgtgcgcg atccgggcgc cgatgccgcg cgcctgaccg
     5521 tgccgcgcac gctcttccgc ggcacgctgc agcgcgacgc cggcaagctt cggttcgccc
     5581 cctgcggcgg cggcaagccc ttcgatgccc gcgacgtctc ggcggagtcg gtgatcaccg
     5641 ccgcggtgac cgatgccggc ttcgatacgc acggcgcgat ctacctcgag gcctggggcg
     5701 agcggcgcgg cggcgagctg cagctcgagc ggctcaaccg tgcggggcac gacctggcct
     5761 gcccgacgag tgcgctcggc gtcgccgcgc agggcaatgc gccgtcctgg cgcctggagt
     5821 cggaccgccg ggcggtacgc ttcagcggcg aaggcggcga gcccctgaac atgccaccgc
     5881 tcccactgtc ctggcactgg cccgtcgggc gccctgaccg cgcggaggcc gtgctcgctg
     5941 gcgcgaccga atccgcgacg ctgcgcctgc ggctctttcc ctcgatctgt cgcgatgcgt
     6001 cgaccggcac ggtgcatggc tttcgcgcgg cgctcgccgt gacacgcgcg ggcccgccgg
     6061 tcgaatacac cggctgcggc cacctcggca acgaagcgct gtattgaagc agcttgctcc
     6121 ggcgcctgca ggtcgtcccc gactcaacgc gcgcccggcg cgatctcata caccggcacg
     6181 aagcccgccg gcggcagcat ccactgcgcc gggaaaagcg ccagcgagcg cttgtccacc
     6241 agctcgacgc tcgggccgag gtagggctcg atcggtcggc cttccagcgc ccgcaaggcc
     6301 tggcgcaccg ccagccggcc ctgcagcacc gggaagtccg tcaccgcggc gaggatgcgg
     6361 ccgcgcagga tgccaccatg gaccgccggg gtgaggtagg aggacacgat cgccgtcgaa
     6421 cctgcgcggc cgcgccggcg tagctcggcg atcgcggcct cggccatggg ggcgttgccg
     6481 accaggtagt cgagctgcgg ctgctcgtcg agcaccgcct cgaccagccg gcgctggatg
     6541 gcgcggccgg tgtcgccgtg gcgctcggcg acgatgcgca ccgcgctgcc ggcgatgccc
     6601 gcgcggaagc cgcggtcgat gaagcccacc cagtccgcat ccaccgggcc ggggacccag
     6661 gcgatgcgcg cggccggggc gccggcgggg tggcgctcgg cgagccagcg gccgatcgtc
     6721 cagccgagct ggtaccaggg tacggcgatg cgcgcccgca ccacctgcgg gtcgatgtcg
     6781 ttcacgaccc cgagcacgag ccggcgctcg agctgcggcg cgagcaggtc gttgagcccg
     6841 ccgcggctga cggtgccgat cagcagcgca tcgaccgccg catccgccag gcacgccgcc
     6901 acgcgctcgc gctggcgggc gagctggccg tagccgccgg cctcgcgcac ccccagcccg
     6961 aggccgagcg cgcgcgcctc ctcggtcatg ccgaagttca ccgccagcca gtagctgtcc
     7021 ttgaggtgcg gatagatcgc gcacaggcgc caggcgcgcg tgggcgaggg cggcgcgatg
     7081 tccggcgccg ccaccgccgc ggcgtcggcc gcgcgatgat cgccctccca gcgttgcacc
     7141 ggccactcgg gcgccggctg cgcgccggca agcgccgcgg cgcagctcag caaggcgccc
     7201 agcgcgaagc cgcgcaaccc gtggcgcacg ctccgccggt aagatgaaac ccgccgactc
     7261 attgccctcg accactgcac aagcgcaccc tttccccacc gaccgtgacc gccccatctt
     7321 acgtgaaacc ccacaccgga cgccgcttcg gcctgcgcga gcgcctgctg ctcggcctgc
     7381 tcgtcgccgc gctcggcacc gtgctggtgg cggtggtggg ctgggtgagc ttccagcgcg
     7441 tggtgagcag ccagcaggcg atcgtgcgcg acaccctgcc ggcggccgac gcgctgcacg
     7501 aggcggtgcg cgccaacgcc cgcctggcgg cgctggcccc gcggctgctg cgggcggact
     7561 cggcggccga gctcgggcag ctgcgcgccg cgctcgacgt cgacgtgccg ctggtgcgcg
     7621 accgcctcgc ggcgctgcgc tcgccccacg tcgaggcggc actgcgtgac cgcctccaat
     7681 cgaccggcga ccgcctcgcc gccgccctcc gcggcatgag cgcggcgatc gcggagcgcc
     7741 tgcggctgcg cgcggcccgt gtcgagcgca tcgacgccct gcgcgcggtg atcgacgagc
     7801 tcgacgagct cgccgggatc cacgccgaca acgccaccgc ccaactcgtg gccacgctca
     7861 ccagcctgct gcaacccgat cccgtccagg gcccccgcag tctcgacgag cgcgaggcgg
     7921 cgcgggagcg cgtactcgac ctcgacatcg acagcctcga acgcatgcac gagctcaacc
     7981 tcaccgtgca tgcgctcggc ttcctcgtcg gccgcctcga tgagctcgac tcgaatgcgc
     8041 ggctgcaggc ggcgcgcggc gagttcgccg aacacctcgc gctgctggcg cgccggctcg
     8101 cggacatccc cgaccccggc ggtcgggagc agggccggca ggtacatcag ctgctcgcct
     8161 ccgcgctcga agacgagggc gccttcgcgc tgcgtgcccg cgagctcgcc ctgcgcgcgc
     8221 aggtggagac cttgcagggc gtggtcggcg agctcaccac cgagctcgac gccctcgctg
     8281 gcgagttgat ccaccgcggc ggccgcctcc tcgccgccgc cggctcagcc gccgagcgca
     8341 gcgccacctc ggggctgatc gccttcggcg tgatcgccgc ggcgctgctg ctggtgacgc
     8401 tcggcgtcac cgtccacgcg ctgcgccgcc acacgctcgg gcgcctgcgt gcgctcgaag
     8461 aggccaccct cgcgctcgcc tccggccggc gcgaggtggc catcgacacc accggcgacg
     8521 acgagctggc ctcgctcgcg gtcgcgctcg aacgcttccg cgccaacgcc atcgagcgcg
     8581 accgcctcgc cgaggcgctg cgcggccagc agcaggagct cgagaaccag gtgctggcgc
     8641 gcaccgcgca gctgcgcgag gccaacgccg cgctcgcccg cgagaccgcc gaccacgccc
     8701 gcgcccgcca cgccgccgaa caggccgacc gcgccaagac cgccttcctc ggcaccgtca
     8761 gccacgagct gcgcaccccg ctcgcgggca tcctcggcct gctcgagctc gtcgaggacg
     8821 ccggctccgc caccgagcgc acgcagtatc aagcgcagat gcgcgccgcg gccgtactgc
     8881 tgctcgagct gctcgaggac atgctcgact tcgcccgcat cgaggccggc ggcgtgcagc
     8941 tcgacaacat gggcttcagc ctgcgcgaca cggtgaacga cgtcttcgcg gtgcagggca
     9001 cgcgcgccgc ggtgcgcggg ctggcgctcg tggccgaggt cgatcccgcg ctgcccgacg
     9061 ccgtgcaggg cgaccgccgc aagctcagcc agatcctgct caacctggtc ggcaacgcga
     9121 tcaagttcag cgacgagggc gcggtgaccg tgcgcgtacg tgccggcacg cagcccggcc
     9181 gcctgcactt cgccgtcgag gatcacggca tcggcatcga gcccgcgcgc cagcaggagg
     9241 tctttgaacc cttcgtgcag gtgcgcgaca gcggccgcca ccacgccggc accggcctcg
     9301 ggctggcggt gtgccgccgc ctggtcgagg ccatgggcgg cgcgatcgag ctgaagagcg
     9361 cgccggggaa gggcaccacg gtgagcttcg agatcgcgct gccggcgacc accgccacgc
     9421 ccgccgaggc cacggccgcc acggccacga ccgacgcgag cgcgccggcc cccggccacc
     9481 gcgtgctggt ggtcgaggac gacgaggtca accgcatggt ggtcgagcgc ttcctcgacg
     9541 ccctcggcca gcaggccgtg tgtgcgcccg acatccacaa cgcgctgcgc ctgctgcacg
     9601 agcgcccgat cgacctcgcc ctcatcgaca tgaacctccc cgacggcgac ggccgcgagt
     9661 tgctcgcccg cctgcgcgcg ctgccggcgc acgcgcgcac cccggcggtg ctgatgtcgg
     9721 cccacatccc gcgccgcgag gtcgatgccc tgctcgaagc cggcttcgcc gccttcctgt
     9781 ccaagccctt ctcgcgccag cgcctgcgcg cgctgctggc caagctgctc tcggggggcc
     9841 gcgccgagcc gccggcgggc gagggcgatc cgggcgcggc cagcgcggcc gaggcggtca
     9901 ccgcagccac agccaccgcc gcgcccgagg cgccgcaggc ggaggactgg atcgacatcg
     9961 acttcctgcg cgcagagcag gaggcgctgg gcgaggagat cgtcgccgac atcgtccgtg
    10021 tcttccgcac gcagggccag ccgctgatcg acgcgctgct cgccgccgcc cgcgcgggcg
    10081 agcaggcgga ctgcgcgcgg ctcgcccaca agctgcgcgg cgccgcgggc aacgtgggcg
    10141 cggggaggct ggcggcgtgc gcggggacgc tggaggacgc gctgaagcgg gaaccatcac
    10201 gggccgcagg ggtcgaggac ctcgccgagc gcgccggcga actcggcggg gcctgggcgc
    10261 acaccctgca ggcactcgac gcgctgcggc ttggggcata ggcacccgcc gcggcagagc
    10321 cggctcagct cccgccggac tccacgtcca ccgccagccg gtaaccctcg ccgcggatgg
    10381 tcgcgatcag cgaatccgcg cgcgccgggt cgtcgagctt ggcgcgcagg cggcgcacca
    10441 gcacatccac cgagcgatcc tgcggcgacc agtcgtgccc gctcaccgcg cgcgacaggc
    10501 ggtctcggtc gaggatctcg ccggggtggc gcaccagcag tgcgagcacc tcgaactcgc
    10561 cgcgcgtcag cgccacgtcc tgccccgcgc ggtcgcgcag ccggcgccgc gacagctcca
    10621 gcacccagcc cgcgaagcgc aggctgtccg ccacctccgc cggccgcgcc ccgctgcgcc
    10681 gcagcaggct cttgacgcgg gccagcaact cgcgcgggtt gaagggcttg gtcacgtagt
    10741 cgtcggcccc cacctcgagc ccgacgatct tgtccacgtc gtcgtcgcgg ctggtgacca
    10801 ggatgatgcc gatcgaggcg tcgcgcgcac gcaactcacg cgccagcgac aagccgtcct
    10861 ggcccgggag gttgatgtcg agcagcacca ggtcgacccc gccctggccg agctgccgcc
    10921 agaacgcttc cccgtcgccc gccagcagca cgcgatagcc ttccttggag aagtaggcat
    10981 tcatgcgcgc ctgcgcgacc agatcgtcgt cgacgacgag gagggtgggg gtggcgtcgg
    11041 gggtggggga catgtgcggg ggagggtagt gtgctctgct acggaatcac ttgcccgcta
    11101 gggcgagcat cgctttcggg ttcgtaccgg cggtcgcgag cagcgcgcga acggacacgc
    11161 ccatactggc cgtcaagtga gacagcgaga aaccggtctt cttgcgcgct tggatgaccg
    11221 gcgaggagac gacaggaagc tcctaagcct tcatctcctg gatcgcttga agcaggagcg
    11281 gtacctcgtt gctcttcggt cgagtacatc ggccattggc ctcggtccag gagcgcttcg
    11341 attgtaagtc agaccgacgt agtatctccc catgaccgga tcgaactgtc ccttctgcca
    11401 gctagacgca gcacgcatcg tgttctcgga cgacgtgacc cttgtgattc gcgatgcctt
    11461 tccagtctcg cccggtcaca ccctgatcat cccgcggcgc cacgtcggat ccttcttcga
    11521 gctgacccca cccgagcgtg cgcgcatgtt cgagctcctg acgcaggcga aggcggaact
    11581 cgatggaacc ctgcagcccg acggcttcaa catcggcatc aacgacggcg cagcggctgg
    11641 acagaccgtg gcgcatctcc atctgcacct gattccacgt tatcgcggtg acacaccgga
    11701 tccacgcggc ggcgtgcggt gggtgcttcc tgccaaggcg aaatactgga gcgggcaatg
    11761 agtctctcca cctacgtcga ccggtttcgg cggctcaacg tcaatgtggc gcacggtcgc
    11821 gccagcccgc acaagatctg catgctgctg gccgtgctcg atctggcgcg gggcggggcg
    11881 ctgacggaaa accgcgtcga gttcgcgccg ccgctgcttg aacgctacgc gctgtatttc
    11941 aatgcggtac gggccgaggg cgaccacccc aatccctact tcccgttctt ccacctcgcg
    12001 ggccgattgc gcggaggcgg cgagagcttc tggcatctgc agccaaagtc ggggcgtgag
    12061 cacgtacttg ccagcatgag cacggcgaga acggtgtggc aggtgacgga caacatcgat
    12121 cacgcgcgac tcgacgcgga gttgttcgat ctgctgcagg atgcgcttgc ggtcgatacc
    12181 ctcagcgcag tgctcgcccc ggatatgcat tgggcgctcg accggcacct gatcgcaccg
    12241 cacagcgact tccgctggcg ggtgagtcgg gcgctggacc ggcgtattcc ggactaccaa
    12301 gtgctgaccg aactggaagg caagccgctg ttcttgccgc gcgaggcgca catgtatccg
    12361 aagcgcgagg cgatcgagtg gcggctggcg atgctggaca cgtgaggtgc gagtagctcc
    12421 ccgtgatggg gtgggatagt ggccgggagc cttgtcagtg atggatgagc gaatgaaaga
    12481 cctgagcccc caacccgctc agtcggcggc cagcagccgc gcgcactcgt ccatcatcga
    12541 gcgcgccaac tccgagtcgt ggttcggatc gagcgcttcc atcatctcgt gcgtggtgta
    12601 gaggcccgcc tcccgtgaca gcgagccggc gatctgtcgc gccaggccgt cgctgagcgc
    12661 ggagagctgg cggcgctccg ccagtggcag tgcgcgctcg ctgcgccgga gccagtcggc
    12721 gatgaagctc gcg
//
LOCUS       DAOTIN010000088        12729 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_5892_length_12729_cov_8.680527, whole genome shotgun sequence.
ACCESSION   DAOTIN010000088 DAOTIN010000000
VERSION     DAOTIN010000088.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 12729)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 12729)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12729
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5892_length_12729_cov_8.680527"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            176..1720
                     /locus_tag="P5537_12285"
     CDS             176..1720
                     /locus_tag="P5537_12285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004385336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052855 - ADP-dependent NAD(P)H-hydrate
                     dehydratase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HRV78861.1"
                     /translation="MFSSLRPIYPVAGIREIEDKLIPNARPPLMERAGRAAAQDAVRL
                     IMDRPGPILVACGPGNNGGDGFVMARQLAQAGREVVVAFCSAAGRLPAEAAKAHADYL
                     AVGGSIVSDMPAAPTNGWALVVDALFGIGLGRPIEGRYASWIHTLNAQPCPRMALDVP
                     SGLDADTGSPLGATFRATHTTTFIALKPGLLTNDGPDHCGEISVQRIEIDAPAWLPAR
                     GHAIAPSLFRHLLQPRPRNTHKGLYGDAAILGGNAGMVGAALLAGRAALWLGTGRVYV
                     GLLDPAGPAVDFAHPELMLRRAETLPERVSALAIGPGLGTDEGAARLLADTLVRPIPL
                     LLDADALNLVAGDAALRQMLCARVTASVLTPHPAEAARLLGTDTASVQADRLRAALEL
                     ARRYRALVVLKGCGSIVATPDERWFINGTGHSGMASAGMGDVLSGLVIGLLAQGWPPE
                     SALIAGVHLHGAAASRLAREGIGPVGLTASETIDAARGVFNGWLIEAHNAALGAATPA
                     RPGAIR"
     gene            complement(1835..2152)
                     /locus_tag="P5537_12290"
                     /pseudo
     CDS             complement(1835..2152)
                     /locus_tag="P5537_12290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018610742.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3D domain-containing protein"
     gene            complement(2717..3583)
                     /locus_tag="P5537_12295"
                     /pseudo
     CDS             complement(2717..3583)
                     /locus_tag="P5537_12295"
                     /inference="COORDINATES: protein motif:HMM:NF015523.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MltA domain-containing protein"
     gene            3861..4352
                     /gene="tssJ"
                     /locus_tag="P5537_12300"
     CDS             3861..4352
                     /gene="tssJ"
                     /locus_tag="P5537_12300"
                     /inference="COORDINATES: protein motif:HMM:TIGR03352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system lipoprotein TssJ"
                     /protein_id="HRV78862.1"
                     /translation="MPLSALWQRWRTRLPILVLVPALLAGCAAPPPKPTVVQASVQAA
                     SGLNPDRRERASPITLRIYELKTDAAFGRADFFSLWDGESATLGADLVARDELQLRPG
                     ETRTLQRTLQPDTREIGVVAAFRDLERAQWRATHVVVPNQTQAVTIQLEARAVRILPA
                     ATR"
     gene            4395..5732
                     /gene="tssK"
                     /locus_tag="P5537_12305"
     CDS             4395..5732
                     /gene="tssK"
                     /locus_tag="P5537_12305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssK"
                     /protein_id="HRV78863.1"
                     /translation="MTMHSKVIWSEGMFLQPQHLQQHDRYVESLVERRAGALRDHAWG
                     WIELVLDEPSLRMGRIALARARGLLPDGTPFDFPAQEEAPGALEIPADARNERVVLAL
                     PLRRPAACETDLFGEDPQGAIRYRPAERELPDNTLAAGPSALVQLGMPCFRLMLARDA
                     TDAYACLGVARVVERRADDQLVLDRDYIPPMLACAGSPVLAAQIGEIHGLLHQRAKAL
                     AARVAQPGRGGVAEIADFLLLQTVNRHEPVFRHYGLRPLLHPEGLYAHCLALAGELST
                     FSRDERRPPEYPPYRHDDLQSCFLPLVADVRRSLSMVLEQTAVPIELQDRKYGVRVAV
                     VPDLELLRSAVFVLAVNAQMPGEALRLRFPGQVKIGPVERIRDLVNLALPGIALRALP
                     VAPRQIPFHAGFNYFELERGGELWKQLQQSGGLALHIAGDFPGLEIECWAIRD"
     gene            5744..7048
                     /locus_tag="P5537_12310"
     CDS             5744..7048
                     /locus_tag="P5537_12310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DotU family type VI secretion system protein"
                     /protein_id="HRV78864.1"
                     /translation="MSNDDPFAAFEPDHTFVMPSPGQRPPQAQGPGRGTEAAGAPAPA
                     VDSLIPAHGINPIVAAASPLLNTVAQIRATLENPDTEALRARLVEAVRAFERKAAQAG
                     VEPRKLVAARYVLCTFLDEAATSTPWGGSGAWARQSLLVSFHNETWGGEKVFQLLARL
                     AEDPAGNRDLLELMHVVLALGFEGRFRVQADGPGQLARLRERLHTLLREQRGDFERDL
                     SPHWVGRPAQRQPLSQLPVWIAFALVGVLAAGLFLFLSERLNARSDPLFSGILALRAA
                     APTPPPTVLAPPPATVPRLASFLEPEIRAGLVAVRDLEDRSVVTIRGDGTFRPGSATL
                     EESVLPLLRRIGEALREVPGPVLITGHTDNVPIRSARFPSNWHLSVERAESVRTLLAG
                     LVAADRLAAEGRADAEPVAGNATPAERARNRRVEITLYRGKP"
     gene            7068..10670
                     /gene="tssM"
                     /locus_tag="P5537_12315"
     CDS             7068..10670
                     /gene="tssM"
                     /locus_tag="P5537_12315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system membrane subunit TssM"
                     /protein_id="HRV78865.1"
                     /translation="MKKLLGLLTHPLLLALIGLGAAAATIWHFGPLLAFAEVRPLETE
                     RARWICIGVLVALWLLRQLWKVFKAGRLNARLVDGLLAARPATPAAAPAPSASEQEVA
                     ALDRRFEEAIGILRGVRLSAAGRRPGLRDLLALSGRQYLYQLPWYVFIGAPGSGKTTA
                     LIHSGLQFPLAEKFGTASLKGVGGTRNCDWWFTDEAVLLDTAGRYTTQESDREVDSAA
                     WQGFLRLLAQARPRRPINGVLLTLSVADLLQQDEGAREAHAAAIRARLQELHDSFQIR
                     LPIYVLVTKADLLAGFTEFFDDLGKDERTQVWGVSLPLADDPKIGTLDGLGSELDLLE
                     ERLLARVPERMHAAGDPARAARVFAFPQQFAVLRAPLVDLLERVFKSSRYDEAPLVRG
                     VYFTSGTQEGSPIDRVLGTLARAIGLERKLLPPQAASGRSYFINRLLREVVFPEQGLA
                     GRNQRLERRLNLLRWSAQGAAVLLLIVAGVAWIGSYQRNDAYLGEVAARIPEVRERLA
                     ALPPPGSTTDLLDLLPVLDAVRGISGGAQAGAPTAGGYGMQQDGKLGAAADQAYRKLL
                     EDALLPRLGLRVEQQLRGAGANNLEFAYEALKAYLVLNDASHFDADALKSWIRFDWER
                     SLPRAATQEQRAELAAHLDRLFERGRVLNPLPHDENLVASVRNLLARYPLANRVYSRL
                     RREGVGEDFPEFTVLRAAGPSAALVFTRVSGQPLTAGVPGLFSHAGYHQAFKRESERV
                     ANQLADEEVWVLGHRDEGAIARLRDTGERSRLIEDVRRLYLNDYARSWEEFLADVKLV
                     RPGNLSQTVDIARLLSAVDSPLPPFLRAAARETTLVPGEADKSIADRAADRLAQETRR
                     LSNLLGGEPSGRPAQPAGDAIENLVDRRFESLRRFVTPPAPGQPAPIDGTLALLGELH
                     VLLTATDTALRAKTALPPSDVPLRVKAQSPGMPEPLRSIVQNLAELSAQLAGGAIVAN
                     LEEAIEAEIGAFCRRAIAGRYPFVRSSARDVTQDDFATLFAPGGKMDQFFQTHLASLV
                     DTSTNPWSFRRLSDVNVGGPGSLVQFQRAQRIREVFFAAGGRTPGLKLEFKPLEMDAS
                     ITQFILDVDGQLVRYGHGPQVPQPVIWPGPRGSTQVRVQVQPPGPTGLSGITTEGPWA
                     LFRLFDRVRMAPTQQAERFLVDFVIDDRRAQFEVTASSVQNPFRLREIEQFQCP"
     gene            10667..11377
                     /gene="tagF"
                     /locus_tag="P5537_12320"
     CDS             10667..11377
                     /gene="tagF"
                     /locus_tag="P5537_12320"
                     /inference="COORDINATES: protein motif:HMM:TIGR03373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system-associated protein
                     TagF"
                     /protein_id="HRV78866.1"
                     /translation="MSDDDLPGWYGKIASLGDFASRRLPAEFISNWDAWLQRMLPDSR
                     ARLGDRWLETYLGSPIWRFLLFPGICGDGLWAGLMMPSVDRVGRYFPLTIASRMPALA
                     STEREFDALADWLDRLSTAALATLDLRRGVQQFDATLTTLRAPLPAPPRVVLAGRIAA
                     LLHDLSPGRFALPSDDELGQTLMGVGAGLLTQHARGGSLWWTPCATGASAPLLLARGL
                     PDGAQFAAMLNAGSTHHA"
     gene            11402..>12729
                     /locus_tag="P5537_12325"
     CDS             11402..>12729
                     /locus_tag="P5537_12325"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018607288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein kinase"
                     /protein_id="HRV78867.1"
                     /translation="MADHNDDKTVIADKTVIVDIPASPSKPAQGAAGQSANMLPVGTR
                     LGEFELIGLVGAGGFGIVYLAEDHSLGRRVALKEYMPAALAQRGEGLRVTLRSERNAE
                     TFEAGRRSFVNEARLLAQFDHPALVKVYRFWEDNGTAYMVMPYYEGVTLKRALLERSA
                     PPDEAWLKRLLAPLLDALEVMHAAQVFHRDIAPDNILLLAGERPLLLDFGAARHVISD
                     MTQALTVILKPGYAPVEQYAEMPELKQGAWTDLYALGAVVHLAITGRVPPPAVGRLVN
                     DSLVPLARQAAGRYTTDFLKAIDRTLAVRPEQRPQSVAELRALLHIAEEGATVPVSTA
                     HRAPAVSAPAGAASAAQPSNSAVHAAPHRRTATWGVAAAGAVAALAALAYLLRDEPTP
                     SVTPEMGARTAPAVSERAPSPPTPAADITPPALPTPAPTPPPAVRARTSAA"
BASE COUNT         1804 a         4947 c         4227 g         1751 t
ORIGIN      
        1 gggctgcggg cgcgtggcgg ttcatgtagg agcgccggca ggcgcgaagg cggcggcgcc
       61 ggacccggcg cgccagcacc ttcccccgcc ccccacattc gccccttccg acgctcctgc
      121 agaaccacca cggccccgag gacgtagaat cgcgactccc ccaccggagt ccatcatgtt
      181 cagctccctg cgcccgatct accccgtcgc cggcatccgc gagatcgagg acaagctcat
      241 cccgaacgct cgcccgccgt tgatggagcg cgctggccgc gccgccgcgc aggacgcggt
      301 gcggctgatc atggaccgcc ccggaccgat cctggtcgcc tgcggtcccg gcaacaacgg
      361 cggcgacggc ttcgtgatgg cacgccagct cgcccaggcc ggacgcgagg tggtggtcgc
      421 gttctgcagc gcggccgggc gtctcccggc cgaggccgcg aaggcgcatg ccgactacct
      481 cgccgtcggc ggcagcatcg tctccgacat gcccgccgca ccgaccaacg gctgggcact
      541 ggtggtcgac gcgctcttcg gcatcggcct cggccgcccg atcgagggcc gctacgcgag
      601 ctggatccac accctcaacg cccagccctg cccgcgcatg gcgctcgacg tcccgagcgg
      661 actcgacgcc gacaccggca gcccgctcgg cgccaccttc cgcgccaccc acaccaccac
      721 cttcatcgcc ctcaagcccg gcctgctcac caacgatggt ccggaccact gcggcgagat
      781 cagcgtgcag cgcatcgaga tcgacgctcc ggcctggcta ccggcgcgcg gccatgcgat
      841 cgccccctcg ctgttccgcc acctgctgca gccacgcccg cgcaacacgc acaagggcct
      901 ctacggcgac gccgccatcc tcggcggaaa tgccggcatg gtcggcgccg cgctgctcgc
      961 agggcgggcc gcgctgtggc tcggcaccgg acgggtgtat gtcggcctgc tcgaccccgc
     1021 cggccctgcg gtcgatttcg cccacccgga gttgatgctg cgtcgcgccg agaccctgcc
     1081 ggagcgggtc agcgcgctcg ccatcggccc cggcctcggc accgacgaag gcgcagcgcg
     1141 tctgctcgcc gatacgctcg tgcgcccgat cccgctgctg ctcgacgccg acgcgctcaa
     1201 cctcgtcgcc ggcgacgccg cactccgtca gatgctgtgc gcgcgcgtca ccgccagcgt
     1261 gctcaccccc catcccgccg aggcggcccg cctgctcggg acagacaccg caagcgtgca
     1321 ggccgatcgc ctgcgtgccg cactcgagct cgcccgccgc taccgcgccc tggtcgtgct
     1381 caagggctgc ggcagcatcg tcgccacgcc cgacgagcgc tggttcatca acggcaccgg
     1441 ccactcgggg atggcgagcg caggcatggg cgacgtgctg agcggcctcg tcattggcct
     1501 gctcgcccaa ggctggcctc cagagtcggc gctgatcgca ggcgtacacc tgcacggcgc
     1561 cgcggccagc cggctcgccc gcgaaggcat cggccccgtg ggactgacgg cgagcgagac
     1621 gatcgacgct gcccgcggcg tcttcaacgg ctggctgatc gaagcgcaca acgccgcgct
     1681 gggggccgcc acgccggccc gcccgggggc gatccgctga ggcgggcgat cactggacat
     1741 cctccacgca cacgccctcc tcctccacca ggcattccgg caagaccgcc gcgccgcgcg
     1801 tgcgcaccac ccggtcgcgc gcggccaccg gcatcccgcg cggcagcagc agccaaaggc
     1861 ggccgcgctc cttcatgcgc gcggcctgag cgaaggcgcg gctgccgagg ccccagaaat
     1921 aatccgcccg aaccgcaccg cgaatcgctc cgccagtgtc ctgcgcgagc accaggcggt
     1981 tgagcggcgc gtccccgcgc ggcaacgtgg tggcgatgaa gaccgggaaa cccagcggca
     2041 tggtccgggg atcgaccgcc accgaacggc cggcggtgag cggcaccccc aaggcgccga
     2101 ccggcccctc gggcccatcg gcgagcgcgc ggaagaagac gtagctcgga tcgccctcga
     2161 tggccgccac cgtcgccgcg ctgggctgcg ggaaccgcat cacctcctcg accgccagcg
     2221 cttccggctc gaccgccacg acgggcgccg acacccgtcc ggccgccccc gccgcgggcg
     2281 catcgacgcc aggcgccggg gccgttgcgg ggcgctttgc ggggcgcgcg ccggggctcg
     2341 ccgccaccgg cgccgaaacc ctgggtggag ccggctcgcg tgatgctggc gccacttccg
     2401 gctgcggccg cgcctggctg ggccggacag tggatccgga cttgagcggg gcctgcgccg
     2461 cgccgacgga tccggtgcgc gcagcctcac ccaacgtggc gcccgcggcg agcgcctcga
     2521 ccaagcgctc cacgtcgcgg tcgagcgcgc gctccgaggg cagcccgggc cgcgcggcgc
     2581 cgcgtgtgag cggccgctcg gcgagcgcgc cctgcgattc ggcgaccgcc tcgaactcga
     2641 tgtcgagccc gcgcgcaaac aacgacggcc cttccgtcat gccgcgcgta cgcgtccgct
     2701 gcggcggccg gaagggatgg ccattctgtt ccgcgaacgc cagccgcagc accttgccgt
     2761 cctcgaggcg cacgcgcccc gagccctgga tgtgcatgga atacagggcc gcgacgttat
     2821 ccacccaggc cagcaccggc gcctggcgca gtcccccacg gacgatctcg gcacgagtcg
     2881 gataggccac caggcgctcc ccctcgaggc gcagccgaac gcggcggtcg agcacgcctg
     2941 ccggcaccgc ggacaggtcg agccgatagg cccccttctc ctccgcagcc ggcaccacct
     3001 tgcggccgac gatgcgcacg ggcaccggcg cagcacgcat ggccttcgga atctggcgta
     3061 gatccagcgt cagcagatcg gccggcaagc catgcaccgg atggacaaag gcgccctgcc
     3121 gactgcgccg cccctcgatg aaaggctcgt agtagcccgt gatgagcccg tcgcgggagc
     3181 gatcggggtt gcctacctcg tagggctcga actcgcgctc gatgaacgcg cgcagcgcat
     3241 cggccccatc caccacgccg agccgggcgc acagcccgct ccacgcatcg ccgcgcccga
     3301 gcgccgtgca actgcgcgcg agcgcctcgc cgacaccggc aagcgcgtcc tgccgccatc
     3361 ccggaacctc gtcccaatcg actggcgcga agtgcgcatg acgggtcgag aacccgctgc
     3421 gcacggtgcc cgcggacttg cccgcatccg tcccggggtc gcccgacacc gctccggcct
     3481 ggcgctcgag cggaagctgt gccggcgtcg ccaccacgct cggggctgcc gagccatccg
     3541 tcccgcttgg cgcgccaagg ggagcggagc cgtccgacag catgctcccg gcactgcagc
     3601 ccgcgagcag gatgaccagc gcgcccgcaa gcgcagaccg tccgatgcaa tgcggttcca
     3661 tgctcaacct ccttcgaccg cgttggcgca cgaccgccga cgccggcacg cgacgaccat
     3721 tcaatccaaa catagtccgc cggcgccacc ctcgccacgc cgaagcacgg cttcatcgac
     3781 gcgcagcgca tatcgcgagg tagacggcgc cggggatagc ggccatattg aattcatatg
     3841 gaaccaccaa ggagagaacc gtgcccctgt ccgcgctctg gcagaggtgg cgcacgcgtc
     3901 tgccgatcct cgtccttgtg ccggcgctgc tggccggctg cgccgccccg ccgcccaagc
     3961 ccaccgtggt gcaggccagc gtgcaggcag cgagcgggct caatccggac cgtcgcgagc
     4021 gcgcctcgcc gatcaccctg cggatctacg agctcaagac cgacgccgct ttcggacgtg
     4081 ccgacttctt ctcgctatgg gacggcgaga gcgcgacgct cggcgccgat ctggtcgcgc
     4141 gcgacgaact ccagctgcgc ccgggcgaaa cccgcaccct gcagcgcacg ctgcagcccg
     4201 acacccgcga aatcggcgtg gttgcggcct tccgcgacct cgagcgtgcg cagtggcgtg
     4261 ccacccatgt cgtcgtgccc aaccagactc aggcggtgac gatccagctc gaggcaagag
     4321 cggtccgtat cctgcctgcg gcgacgaggt gacaacgggc gcgacccacg catggccaag
     4381 cagcgaggac gctaatgacg atgcacagca aggtgatctg gtccgagggc atgttcctgc
     4441 agccgcagca cctgcagcag cacgaccgct atgtcgagtc gctggtcgag cgccgcgcgg
     4501 gcgcgctgcg tgatcacgcc tggggctgga tcgagttggt gctggacgag ccctcgctgc
     4561 gcatggggcg gatcgcgctc gcgcgcgcgc gcggcctgtt gcccgacggc acgcccttcg
     4621 acttcccggc gcaggaggag gcaccgggcg cgctcgagat cccggctgac gcgcgcaacg
     4681 aacgcgtggt cctcgcgctg ccgctgcgcc gccccgcggc ctgcgagacc gacctcttcg
     4741 gcgaagatcc gcagggcgcc atccgctacc ggcccgcaga acgcgaactc ccggacaaca
     4801 ccctcgccgc cggcccgagc gcgttggtcc agctcggcat gccgtgcttc cgcctgatgc
     4861 tcgcgcgcga cgccaccgat gcctatgcct gcctcggcgt cgcacgcgtc gtcgagcgcc
     4921 gggccgacga ccagctcgtg ctcgaccgcg actacatccc ccccatgctc gcgtgcgccg
     4981 gcagcccggt gctcgctgcg cagatcggcg agatccacgg cctcctccac cagcgtgcga
     5041 aagccctggc ggcgcgcgtg gcccagcccg ggcgcggcgg cgtggccgag atcgccgact
     5101 tcctcctgct gcagacggtg aaccggcacg agccggtctt ccgccattat ggcctgcgcc
     5161 ccctgctgca tcccgagggc ctgtatgcgc attgcctggc gctcgccggc gaactctcca
     5221 ccttctcgcg cgacgaacgg cgtccgcccg aataccctcc gtatcgtcac gacgatctcc
     5281 agtcctgctt cctgccgctg gtagccgacg tgcggcgctc gctgtcgatg gtgctcgagc
     5341 agaccgccgt gcccatcgag ctgcaggatc gcaagtacgg cgtgcgggtc gcggtggtgc
     5401 ccgacctcga gctgctgcgc agcgccgtct tcgtgcttgc ggtcaacgcc cagatgcccg
     5461 gcgaggccct gcgcctgcgt tttcccgggc aggtcaagat cggccccgtc gagcgcatcc
     5521 gcgatctggt caacctcgcc ctgcccggca ttgccctgcg cgccttgccg gtggcaccgc
     5581 ggcagatccc cttccacgcc gggttcaact atttcgagct cgagcgtggc ggcgagctgt
     5641 ggaagcagct gcagcagtcc ggcggcctgg cgctgcacat cgcaggcgat tttcccgggc
     5701 tggagatcga atgctgggcg atccgtgact gagagaggcc gtcatgagca acgatgaccc
     5761 ctttgcggcc ttcgaacccg accacacctt cgtcatgccc tcacccggcc agcgtccccc
     5821 ccaggcgcag ggcccgggcc gcggcacgga agcggcgggc gctccggcgc cggcggtgga
     5881 cagcctgatt cccgcgcacg ggatcaaccc gatcgtcgcc gcagccagcc ctctgctcaa
     5941 caccgtcgcg cagatccgcg ccacgctcga gaaccccgac accgaagcct tgcgtgcacg
     6001 cctcgtcgag gccgtccgcg ccttcgagcg caaggctgca caggcggggg tcgagccgcg
     6061 caagctggtg gccgcgcgct acgtgctgtg caccttcctc gacgaggcgg cgaccagcac
     6121 gccctggggc ggctcggggg cgtgggcgcg gcaaagcctg ctggtcagct ttcacaacga
     6181 gacctggggc ggcgaaaaag tcttccagtt gctggcacgc ctggccgagg accctgcggg
     6241 caatcgcgac ctgctcgagt tgatgcacgt ggtgctcgcg ctcggcttcg aggggcgctt
     6301 ccgggtgcag gcagatggtc cggggcagct ggcacgcctg cgcgaacgcc tgcacaccct
     6361 gctgcgcgag cagcgcggcg acttcgagcg cgacctctcg ccgcactggg tcgggcggcc
     6421 cgcgcagcgc cagcccctgt cccagctgcc ggtgtggatc gccttcgcgc tcgtgggcgt
     6481 gctcgccgcg gggctcttcc tgttcctgtc cgagcggctc aacgcgcgct ccgacccgct
     6541 cttctcaggc atcctcgcct tgcgcgcggc cgccccgacg ccgccgccca cggtgctcgc
     6601 accgccgccc gccacggtgc cgcggctcgc gagcttcctc gagccggaga tccgtgccgg
     6661 gttggtggcg gtgcgcgacc tggaggaccg cagcgtggtg accatccgcg gcgacggcac
     6721 cttccgcccg ggcagcgcga cgctcgagga gtccgtcctc ccgctcctgc gccgcatcgg
     6781 cgaggcgctc cgcgaggtgc ccggtccggt cctgatcacc gggcacaccg acaacgtgcc
     6841 gatccgctcc gcccgcttcc cctcgaactg gcacctttcg gtcgaacgcg ccgagtcggt
     6901 gcgtaccctg ctcgccgggc tggtcgcggc agaccggctc gctgcggagg ggcgtgccga
     6961 cgccgaaccc gtggcgggca acgccacccc ggccgaacgc gcgcgcaacc gccgggtcga
     7021 gatcaccctc taccgcggca agccttgatc tgccgagagt ccgaaccatg aagaaactac
     7081 tcggcctgct gacccacccg ctgctgctcg cgctgatcgg gctgggtgcg gctgcggcga
     7141 ccatctggca cttcgggccg ctgctggcct tcgccgaggt cagaccgctc gaaaccgaac
     7201 gtgcgcgctg gatctgcatc ggcgtgctgg tcgcgctgtg gctgctgcgc cagctgtgga
     7261 aggtgttcaa ggccggacgc ctgaacgcgc gcctggttga cggcctgctc gccgccaggc
     7321 cggcgacgcc cgccgccgcg cccgccccct cggcctcgga acaggaggtc gccgcgctcg
     7381 accgccgctt cgaggaggcg atcggcatcc tgcgcggcgt gcgcctgtct gccgccggcc
     7441 gccgccccgg cctgcgcgat ctgctcgcgc tctccgggcg ccagtatctc tatcagctgc
     7501 cgtggtatgt cttcatcggc gcccccggct cgggaaagac caccgcgctg atccattccg
     7561 ggctccagtt tccgctcgcc gagaagttcg gcaccgcctc gctcaagggg gtgggaggca
     7621 cgcgcaattg cgactggtgg ttcaccgacg aggcggtgct gctcgacacc gccgggcgct
     7681 acaccacgca ggaatccgac cgcgaggtcg acagcgccgc ctggcagggt ttcctgcgac
     7741 tgctcgccca ggcgcggcca cgccggccga tcaacggcgt cttgctcacg ctcagtgtcg
     7801 ccgacctgct gcagcaggac gagggcgcgc gcgaggccca tgccgccgcg atccgggctc
     7861 gcctgcagga actgcacgac agcttccaga tccgcctgcc gatctatgtg ctggtgacca
     7921 aggccgacct gctcgccggc ttcaccgagt tcttcgacga tctgggcaag gacgagcgca
     7981 cccaggtctg gggggtgagc ctgccgcttg ccgacgaccc gaagatcggc accctggacg
     8041 gcctcggtag cgaactcgac ctgctcgagg agcgcctgct cgcccgggtg cccgagcgca
     8101 tgcacgcggc cggggacccc gcgcgtgctg cgcgcgtgtt cgccttcccg cagcagttcg
     8161 cggtgttgcg cgccccgctg gtggatctgc tcgaacgcgt cttcaagtcc tcgcgctacg
     8221 acgaggcccc gctggtgcgc ggcgtctact tcaccagcgg cacccaggag ggcagcccga
     8281 tcgaccgcgt gctcggcacc ctcgcgcgcg cgatcgggct cgaacgcaag ctcctgccgc
     8341 cgcaggcggc gagcggacgc agctacttca tcaaccgcct gctgcgcgag gtcgtcttcc
     8401 ccgagcaggg cctggccggt cgcaaccagc gcctcgagcg ccgcctcaac ctgctgcgct
     8461 ggtccgccca gggcgcagcg gtcctgctcc tgatcgtcgc cggcgtcgcc tggatcggca
     8521 gctaccagcg caacgacgcg tacctgggcg aggtcgccgc ccgcatcccc gaagtgcgcg
     8581 agcgcctcgc ggcgctgccg ccgccgggca gcaccaccga cctgctcgac ctgctgcccg
     8641 tgctcgatgc ggtgcgcgga atctcgggcg gtgcgcaggc cggtgccccg accgcaggcg
     8701 gctacggcat gcagcaggac ggcaagctcg gcgcggctgc cgaccaggcc taccgcaagc
     8761 tgctcgaaga cgccctgctg ccgcggctcg gcctgcgcgt cgagcagcag ctgcgcggcg
     8821 ccggcgcgaa caacctcgag ttcgcctacg aggccctcaa ggcctacctg gtgctgaacg
     8881 acgcgagcca cttcgacgcc gacgcgctga agtcctggat ccgcttcgac tgggaacgca
     8941 gcctgccgcg cgcggcgacg caggaacagc gcgccgaact cgccgcccac ctcgaccgcc
     9001 tcttcgagcg cggacgagtg ctcaacccgc tgccgcatga cgagaacctg gtcgcctcgg
     9061 tgcgcaacct gctcgcgcgc tatccgctcg caaaccgcgt ctacagccgg ctacggcgcg
     9121 aaggcgtggg cgaggacttt cccgagttca ccgtgctgcg cgccgcgggg ccgtcggcgg
     9181 cgctggtctt cacccgcgtc tcgggccagc cgctcaccgc cggcgtgccc gggctgttca
     9241 gccatgcggg ctaccaccag gcgttcaagc gcgaatccga gcgggtggcc aaccagctcg
     9301 ccgacgagga ggtctgggtg ctcggccatc gcgacgaggg tgcgatcgca cgcctgcgcg
     9361 acacgggcga acgcagccgc ctgatcgagg acgtgcggcg gctctacctc aacgactacg
     9421 cgcggagctg ggaggaattc ctcgccgacg tcaagctcgt acgccccggc aacctctcgc
     9481 agacggtcga catcgcccgc ctgctctcgg cggtggacag cccgctgccg cccttcctgc
     9541 gtgctgcggc gcgcgagacc acgctggttc cgggcgaggc cgacaagagc atcgccgacc
     9601 gcgccgccga ccgtctcgcc caggagaccc ggcgactgag caacctgctc ggcggcgagc
     9661 ccagcggccg accggcgcag cccgcaggcg acgcgatcga gaacctcgtc gaccgccgct
     9721 tcgagagcct gcgccgcttc gtgaccccgc ccgctcccgg ccagccggcg ccgatcgacg
     9781 gcacgctcgc cctgctcggc gagctgcacg tgttgctcac cgccaccgac accgcgctgc
     9841 gcgccaagac cgcgctgccg ccatcggatg tgccgctgcg ggtgaaggcg cagtcgccgg
     9901 gcatgcccga gccgctgcgc tcgatcgtgc agaacctggc cgagctcagc gcccagctgg
     9961 ccggcggcgc catcgtcgcc aacctcgagg aggccatcga agccgagatc ggtgcgttct
    10021 gccgccgtgc gatcgccgga cgctatccct tcgtccgcag ctcggcgcgt gacgtgaccc
    10081 aggacgactt cgccaccctg ttcgctcctg gcggcaagat ggaccagttc ttccagaccc
    10141 atctcgccag tctggtcgac acgtcgacca acccttggag cttccgccgc ctcagcgacg
    10201 tgaacgtcgg cggaccgggt tcgctggtgc agttccagcg cgcgcaacgg atccgcgagg
    10261 tcttcttcgc cgcgggcggg cgcacgccgg gcctcaagct cgagttcaag ccgctggaga
    10321 tggatgcatc gatcacccag ttcatcctcg acgtggacgg gcaactggtg cggtacggcc
    10381 atggaccgca ggtgccgcaa ccggtcatat ggcccggccc gcgcggcagc acccaggtgc
    10441 gtgtacaggt gcagcctccg ggccccaccg gcctctcggg catcaccacc gagggtccgt
    10501 gggcgctgtt ccgcctcttc gaccgcgtgc gcatggcgcc cacgcagcag gccgaacgtt
    10561 tcctcgtcga cttcgtgatc gacgaccgcc gcgcccagtt cgaggtcacc gccagcagcg
    10621 tccagaaccc cttccgcctg cgggaaatcg agcagttcca gtgcccatga gcgacgacga
    10681 cctccccggc tggtacggca agatcgcgag cctcggcgac ttcgcctcgc gccgcctgcc
    10741 tgccgagttc atctcgaact gggacgcctg gctgcagcgc atgttgcccg attcgcgcgc
    10801 gcgtctgggc gatcgctggc tggagactta cctcggcagc ccgatctggc gcttcctgct
    10861 cttccctggt atctgcggtg acggcctgtg ggcggggctg atgatgccca gcgtcgaccg
    10921 cgtagggcgc tatttcccgc tcaccatcgc atcccgcatg ccggcgctcg catcgaccga
    10981 acgcgaattc gacgccctcg ccgactggct cgaccgcctg tccaccgccg cactggccac
    11041 gctcgacttg cggcgcggcg tgcagcagtt cgacgccacg ctgacgacgc tgcgcgcgcc
    11101 cctccccgcc ccgccacgag tggtgctggc cgggcggatc gcggcgctgc tgcacgacct
    11161 ttcgccgggg cggttcgcgc tgccctccga cgacgaactc ggccagacgc tgatgggcgt
    11221 cggggcgggc ctgctgaccc aacatgcacg cggcggctcg ctgtggtgga ccccgtgcgc
    11281 cacgggggcg agcgcgcccc tcctgctggc ccgcgggctt ccggacggcg cacagttcgc
    11341 cgccatgctg aacgcgggca gtacccacca cgcctgacgc cgaccccacc cggagcccgc
    11401 catggccgac cataacgacg acaagaccgt gatcgccgac aagacggtga tcgtcgacat
    11461 cccggcgagt ccctccaaac ccgcgcaggg cgctgccggc caatccgcga acatgctgcc
    11521 ggtcggcacc cgcctgggcg aattcgagct catcggcctg gtcggtgccg gcgggttcgg
    11581 catcgtctat ctggccgagg accattccct cggccgccgc gtcgccctca aggaatacat
    11641 gccggccgcc ctcgcgcagc gcggcgaggg cctgcgcgtc accctgcgct cggagcgcaa
    11701 cgccgagacc ttcgaggccg gcaggcgcag cttcgtaaac gaggcccggc tgctcgccca
    11761 gttcgatcat cccgccctgg tgaaggtcta tcgcttctgg gaggacaacg gcaccgccta
    11821 catggtgatg ccctactacg aaggcgtcac gctcaagcga gccctgctcg agcgcagcgc
    11881 tccgcccgac gaggcgtggc tgaagcgact gctcgccccg ctgctggacg cgctggaggt
    11941 gatgcatgcg gcgcaggtct tccaccgcga catcgcaccc gacaacatcc tgctgctcgc
    12001 cggagaacgt cccttgctgc tcgacttcgg cgcagcacgg cacgtgatct cggacatgac
    12061 gcaggcgctc acggtgatcc tcaagcccgg ctacgccccg gtcgagcagt acgccgagat
    12121 gcccgaactc aagcaagggg cgtggaccga cctctacgcg ctcggcgccg tcgtacacct
    12181 ggccatcacg ggtcgtgtcc cgccgccggc cgtcggccgc ctggtgaatg actccctcgt
    12241 cccgctcgcg cggcaggccg cggggcgtta caccacagac ttcctgaagg cgatcgaccg
    12301 cacgctcgcg gtgcgccccg aacagcgccc ccagagcgtg gccgagctcc gcgccctgct
    12361 gcacatcgcg gaggaaggcg ccacggtgcc ggtgtccaca gcgcacaggg cacccgccgt
    12421 ctcggcgccg gcaggcgctg cgagcgcggc gcagccatcg aattccgccg tgcatgccgc
    12481 accgcaccgc cgcaccgcga catggggcgt cgccgccgca ggtgcggtgg cagcgctggc
    12541 ggcgctcgcc tacctgttgc gcgacgagcc caccccatcc gtgacgccgg agatgggcgc
    12601 ccggactgca cctgcggtgt cggagcgcgc accgagcccc cccacgcctg ccgccgacat
    12661 cacgccgccc gccctgccaa cgcctgcccc gacgccgccc cccgccgtca gggcaagaac
    12721 cagtgccgc
//
LOCUS       DAOTIN010000089        12623 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_5947_length_12623_cov_8.645926, whole genome shotgun sequence.
ACCESSION   DAOTIN010000089 DAOTIN010000000
VERSION     DAOTIN010000089.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 12623)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 12623)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12623
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5947_length_12623_cov_8.645926"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..285)
                     /locus_tag="P5537_12330"
     CDS             complement(<1..285)
                     /locus_tag="P5537_12330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004371268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HRV78868.1"
                     /translation="MTVRTLLRMGDARLLQPAAPVGEFGTPELAGLVEDMFDTMAAHG
                     GVGLAAPQIGVGLQVVIFGFEHSERYPDAAPVPRTILVNPVITPLTEDREE"
     gene            complement(307..1212)
                     /locus_tag="P5537_12335"
     CDS             complement(307..1212)
                     /locus_tag="P5537_12335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HRV78869.1"
                     /translation="MSVQGPGGAAPNRLEADLLLTLTTLIAAAGWIFSKEALAGIPPL
                     IFIGLRFTIAGLVLAMFSLPQLRALDRRALRNSLLVGALFAGGMVLWILGLSHSSHLG
                     EASFISSMGIVMVPVFARLFFGDRPPASTWVALPLALAGFACLSLDGGFEVEPGQLFF
                     LGAALVFALMFNVNSHVVRNVPVRALSVVQMLAVGVLVLPPALLIEPWPETWGAPVLG
                     WLLASALLATTLRFLLQLHGQSLTTPSHAALIMMLEPVWTALAAAWWFAETMSALQLA
                     GCGLIFLALVVSRWAWLRGLFGGRG"
     gene            complement(1209..1619)
                     /locus_tag="P5537_12340"
     CDS             complement(1209..1619)
                     /locus_tag="P5537_12340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HRV78870.1"
                     /translation="MSASGGLARFLRFAAVGAVGTLAHYALLVALVEGAGAPPLAGAT
                     AGFVLGALVNYALARRLVFASTRSHAQALPRFFAVALAGLAWTALLMSLFMELLGLHY
                     LLAQVLTTALLLLWHYAGNALWTFRSRRRDVEVR"
     gene            complement(1616..3277)
                     /locus_tag="P5537_12345"
     CDS             complement(1616..3277)
                     /locus_tag="P5537_12345"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 39 protein"
                     /protein_id="HRV78871.1"
                     /translation="MIPPRAAARAPAAAGEAPAVTLEAATHGALARRIALAVLALAGM
                     FVLLTFDRHGISNDEEVQHVYGRLLLDFYLSGFADRQAFEYKNLYLYGGFFDLVAAAL
                     ERAGAAEGPALWDLRHLISAGFGLLGLAGTWLLARRLAGEWAGLAALVLLLITGSWSG
                     AMFTHTKDIPFATTMLWALYFSVRVLDTLPAPPWRVLAGLGVALGCAFGLRIGAVFAV
                     FYLGVGMLAAAALQAHGRLRFLLRGVLALLPAAAIALALGALFWPWAAMAPGNVFTAM
                     SAFSHFSFDLDTVLAGRVMNVGEVPGHYLAAYLLVRLPELFLAGVALALLAGVRALAA
                     LATAPGRRSALPWLPVVLAALFPLAYTLVAAPPLYNGLRHFSFVLPPLAVLAGAGLVH
                     AWQGLRARPPLLRRAVLLACALAVLGQAGLLARLHPYGYLAYNQLVGGVPGAAGGWEQ
                     DYWASSLREAVLALNALVAREGVPAQGYAVAVCAEPLQAQVWLAPGLRATRDWWGADF
                     YLSPTHMGCEQALQGRVVAQVERAGRVLAVVKDRRALVGEDRRPR"
     gene            complement(3274..4284)
                     /locus_tag="P5537_12350"
     CDS             complement(3274..4284)
                     /locus_tag="P5537_12350"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HRV78872.1"
                     /translation="MSHSDSLDAHPHVPPASSAHPRLSVVVPVYNEGETVEALHRRLS
                     QVLAGLELSGWDIVCVDDGSRDDTYARVATLCAGDRHLKAIRFARNFGKEAAMAAGLQ
                     AATGDVIVLMDGDLQHPPELIPEMLARWRGGAMMVTAVRRSRVTDPWLRRKLTRGFYA
                     FFSKVSEVELAEGGGDFRVFDRAVVDAINSLPERTRFMKGITSWVGFRQEVVEFEPAQ
                     RAGGVSGWSMLRLLRYAIDGLSAFSTLPLRVWSVIGLMMAGLSGLYGVFLVLRTMLFG
                     IDLPGYVSLMVSGLFLSGIQLISLGVLGEYVGRIFTEVKGRPLFLVSERLGFERRPER
                     DR"
     gene            4420..5334
                     /locus_tag="P5537_12355"
     CDS             4420..5334
                     /locus_tag="P5537_12355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
                     /protein_id="HRV78873.1"
                     /translation="MQAPSRPGAPATRPVVVCADDYGLAPGVSEAIAALVATGRLSAT
                     SCMSALPDWHRAAPPLRALMASAPADVGLHLTLTDQPPLSAAARRAWGERLPPLGRLL
                     AAALARRLPAQAVADEIRAQLDAFEDAWGDAPDHVDGHQHVHVLPGVRERLVAELLRR
                     HPRGRVWVRDCVEPPLRSLQRREAAGKAWFISALARGLHRQLREAGLPCNEGFSGLHD
                     FSVERPFAAKMRRFLAGTGPRPLVHVHPGRVDAALRACDPLTTPREAELAYLASAEYL
                     ADLAAAGLRPARFAAFDAPEVGTTAPSC"
     gene            5479..6435
                     /gene="gluQRS"
                     /locus_tag="P5537_12360"
     CDS             5479..6435
                     /gene="gluQRS"
                     /locus_tag="P5537_12360"
                     /EC_number="6.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA glutamyl-Q(34) synthetase GluQRS"
                     /protein_id="HRV78874.1"
                     /translation="MQPSIPSPDPDAGLLASPCANPYVGRFAPSPSGALHFGSLVAAV
                     GSFLDARAHGGRWLLRIEDVDTPRTVPGAAAGILATLERFGFEWDGAIVRQSERGEAY
                     AAALERLRAAGLAYPCACTRRELAGQPLARDGSRRYPGTCRDGLPPGRTGRAWRVRAE
                     GVVRFCDAVQGEQEIDLAADAGDYVVKRADGLFAYQLAVVVDDAEAGVTHVVRGADLL
                     DSTARQIHLLGLLGHPVPAYAHLPLATNPAGEKLSKQTLARAIDEHPPQAALLAALRF
                     LGHNPPDMLTAAPLVETWAWARAHWSLAAVPRRRQAVADGFF"
     gene            6445..6867
                     /locus_tag="P5537_12365"
     CDS             6445..6867
                     /locus_tag="P5537_12365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HRV78875.1"
                     /translation="MHPNDISTQPEAIRSLLQQARTIAVVGISARHDRPSHEVAHYLQ
                     RAGYTIIPVNPAYEEVLGQKCYPNLHEVPVKIDLVDVFRKPAEVMAVVDEAIAVGAGS
                     VWLQLGVIAPDAADKAAAAGLKVVSDRCTKIEHRRLIG"
     assembly_gap    7169..7268
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<7269..8182)
                     /gene="clsB"
                     /locus_tag="P5537_12370"
     CDS             complement(<7269..8182)
                     /gene="clsB"
                     /locus_tag="P5537_12370"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase ClsB"
                     /protein_id="HRV78876.1"
                     /translation="MQFIAGNAVALLENGGQYFPALEAEIDRAEREIFLQSYIFEDDG
                     TGARIAAALARAAGRGVAVRVMVDGFGGRNFVPTLMPRLREAGVQVLIYRRELRPLSL
                     RRHRLRRLHRKVVAIDGRVAFVGGINVVDDFDAGALANPRYDYAVRVEGPVLAPVVAS
                     AQRLWRLVAWASFRRRAAQPLLAPPRTEAAGSIRATFVVRDNLRHRHAIEEAYLEAIA
                     GAREEIVLANAYFFPGRRFRQALIDAARRGVRVTLLLQGVSDHPMQVYATRALYPIFL
                     DAGIRLFEYHRSHLHAKVAVIDHQWATVG"
     gene            complement(8182..8931)
                     /locus_tag="P5537_12375"
     CDS             complement(8182..8931)
                     /locus_tag="P5537_12375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HRV78877.1"
                     /translation="MALRICSYNIHKGFSQFNRRMVVHELRDRLRSLDADLVFLQEVQ
                     GLHLRHPARHPDWPALPQHEFLAEDAWQEIAYGGNAIYDHGHHGNAILSRHLILSTAN
                     QDVSDHRFERRGLLHCEVRLPEFDVPVHCVCVHLGLMAGSRRRQMEALAERMEELAPG
                     NAPLIIAGDFNDWRNRADDLLGRRLGLAEAFGSGRGRPARSYPSTLPFFRLDRIYVRG
                     FRVRQAQVHYGAPWAQISDHAALTADLEPIG"
     gene            complement(8957..10057)
                     /gene="nadA"
                     /locus_tag="P5537_12380"
     CDS             complement(8957..10057)
                     /gene="nadA"
                     /locus_tag="P5537_12380"
                     /EC_number="2.5.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002931115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HRV78878.1"
                     /translation="MQVSTISFDRFNVLADNEAQERIRAARARLGERAVLLCHHYQRA
                     DVYQHADLTGDSLKLARLASQTDAEFIVFCGVHFMAEVADILSKPSQIAILPDLAAGC
                     SMADMASLAKVERCWRELAEVLDKPDEIITPVTYINSAADLKAFCGEHGGIVCTSTNA
                     PTILDWAFAKREKVLFFPDQHLGRWTGFKKGIPLDEMVVWDPDLEYGGLTAEQIRKAK
                     ILLWKGHCSVHQMFQPVHIDRWREKHPHGFVISHPESMLEVCQKSDYVGSTEFILNTI
                     TQAPPNTHWLVGTELNLVSRLAEEMKPQGKVVQFMAPTVCMCSTMQRIDPQHLAWTLE
                     NLAEGKVVNQIKVPAHEAELARIALDRMLAVS"
     gene            complement(10174..10626)
                     /locus_tag="P5537_12385"
     CDS             complement(10174..10626)
                     /locus_tag="P5537_12385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HRV78879.1"
                     /translation="MGTLSELLTLAHERAESLGLPYQGALTPAETWQVMQLAPGAKLV
                     DVRTRAELDWVGRVPGAIEIEWKSYPSMQENPNFLAQLKHQVDPEALVLFLCRSAVRS
                     DSAARLASANGYANCYNVLEGFEGDKDANNQRNRIGGWRLAGLPWYQG"
     gene            10686..11873
                     /locus_tag="P5537_12390"
     CDS             10686..11873
                     /locus_tag="P5537_12390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HRV78880.1"
                     /translation="MPSRQAHSPVPAAPAATDELARSRGIQRATLVAILTNSLLTIGQ
                     VVIGLFAGAFSLVADAAHTLSDLVTDLLVLLAGRHSADPADTNHPYGHGRIETVTTLV
                     LGAVLGAVGVGFLWSSGIRLQDIEALPVLHPAALVMALLTLAAKEGLFRYTLAAARRL
                     NAPMLEANAWHARSDAASSLVVAAGIGGSLAGYPFLEPLAAAVVGFLILHMGLRLAWK
                     SIGELIDTGLPEEELERLRATIRETPGVIGLHDMRTRRMADRVLCDAHVQVDPRLTVS
                     EGHRVSDAVYLRVRAAHPEVRDVLVHIDPEDDGELQVVPPGPLPERVEILARMRELLG
                     PAFAEPRRVQIHYLGQRVEVEIILPSAPAAEALEMLQSRRKAWLAEHPHYRNIRVFVE
                     TAP"
     gene            12092..>12623
                     /locus_tag="P5537_12395"
     CDS             12092..>12623
                     /locus_tag="P5537_12395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015434326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0006807 - nitrogen compound metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase beta-grasp
                     domain-containing protein"
                     /protein_id="HRV78881.1"
                     /translation="MNAQDVMKMIQENEVRFVDLRFTDIRGKEHHVGLPVSAFEEEHF
                     EHGHPFDGSSLAGWKGIQASDMILMPEPSTAYIDPFFDETTLVITCDVIEPSDGKGYD
                     RDPRSIAKRAEAYLKSTGIGDTAFFGPEPEFFIFDSVEWSVDMSGVYSKIISEEAAWS
                     TADKFEGGNTGHRPRVK"
BASE COUNT         1945 a         4593 c         4333 g         1652 t
ORIGIN      
        1 ctcctcgcgg tcctcggtga gcggcgtgat caccgggttc accaggatgg tgcgcggcac
       61 cggcgcggcg tccgggtagc gctcgctgtg ctcgaagccg aagatcacca cctgcaggcc
      121 gacgccgatc tgcggcgcgg ccaggcccac gccgccgtgc gcggccatgg tgtcgaacat
      181 atcctcgacc agccccgcga gttcgggcgt gccgaactcg ccgaccggcg cggcaggctg
      241 cagcagtcgc gcatcgccca tgcgcagaag ggtacggaca gtcatcggct ctctctcctc
      301 gttcgttcag ccgcgcccgc cgaagaggcc gcggagccac gcccagcggc tcaccaccag
      361 ggcgaggaag atcagcccgc agccggcgag ctgcagcgcg ctcatggtct cggcgaacca
      421 ccacgccgcg gcgagcgcgg tccataccgg ctcgagcatc atgatcagcg cggcgtggct
      481 gggcgtggtc aggctctggc cgtggagctg gagcaggaag cgcagcgtgg tggcgagcag
      541 cgcgctcgcg agcagccagc cgaggaccgg cgcgccccag gtctcgggcc agggctcgat
      601 cagcaaggcc ggtggcagca ccagcacgcc gacggcgagc atctgcacca cgctgagcgc
      661 gcgcaccggc acgttgcgca cgacgtgcga gttgacgttg aacatcagcg cgaacaccag
      721 cgcggcgccg aggaagaaca gctggccggg ctcgacctcg aagccgccgt cgagcgacag
      781 gcaggcgaag ccggcgagcg cgagcggcag cgcgacccag gtgctcgccg gcggacggtc
      841 gccgaagaac aggcgcgcga acaccggcac catgacgatg cccatgctgg agatgaacga
      901 ggcttcgccg aggtggctgc tgtgcgacag gccgaggatc cacagcacca tgccgccggc
      961 gaacagggcg ccgacgagca ggctgttgcg cagcgcgcgc cgatcgagcg cgcgcagctg
     1021 cggcagcgag aacattgcca gcaccagccc ggcgatcgtg aagcgcaggc cgatgaagat
     1081 cagcggcggg atgcctgcga gcgcctcctt ggagaagatc cagcccgccg ccgcgatcaa
     1141 cgtggtgagg gtgagcagga ggtcggcctc gagccgattc ggcgccgcgc cgccggggcc
     1201 ctgcacgctc atcgcacctc cacgtcgcgg cgacggctgc ggaaggtcca cagggcgttg
     1261 ccagcgtaat gccagagcag cagcagcgcg gtggtcagca cctgggcgag caggtagtgc
     1321 aggccgagca gttccatgaa caggctcatc agcagcgccg tccacgccag cccggccagc
     1381 gccacggcga agaagcgcgg cagcgcctgg gcgtggctgc gggtggaggc gaacaccagc
     1441 cggcgcgcga gcgcatagtt gaccagcgcg ccgagcacga agccggcggt cgcgcccgcc
     1501 agcggcggcg cgcccgcgcc ctccacgagc gcgaccagca aggcgtagtg ggcgagcgtg
     1561 cccaccgccc cgaccgcggc aaagcgcagg aagcgcgcca gccccccgga tgcgctcatc
     1621 gcggcctcct gtcctcgccg accagcgcgc ggcgatcctt gacgaccgcc agcacccgcc
     1681 ccgcgcgctc cacctgcgcc accacgcgcc cctgcagcgc ctgctcacaa cccatgtggg
     1741 tgggcgagag gtagaagtcc gcgccccacc agtcgcgcgt cgcgcgcagc ccgggcgcga
     1801 gccagacctg cgcctgcaac ggctcggcgc acaccgccac ggcgtagccc tgcgccggca
     1861 cgccctcgcg cgcgaccagg gcgttgagcg caagcaccgc ctcgcgcagg ctgctcgccc
     1921 agtagtcctg ctcccagccc ccggccgctc ccggcacacc gccgacgagc tggttgtagg
     1981 cgagatatcc gtaaggatgc aggcgggcga gcaggcccgc ctggccgagc accgccagcg
     2041 cgcacgcgag cagcacggcg cggcgcagca gcggcggacg ggcccgcagg ccctgccagg
     2101 catggaccag ccccgcgccc gccagcaccg cgagcggcgg cagcacgaag ctgaaatggc
     2161 gcaggccgtt gtacagcggc ggcgctgcga ccagggtgta ggcgagcggg aacagcgccg
     2221 ccagcaccac cggcagccag ggcagggccg atcgtcggcc cggcgccgtg gcgagcgccg
     2281 ccagggcgcg cacaccggcg agcagcgcca gcgcgacccc ggcgaggaac agctccggca
     2341 ggcgcaccag caggtaggcc gcgaggtaat ggcccggcac ctcgccgacg ttcatcacgc
     2401 gcccggccag caccgtgtcg aggtcgaaac tgaaatgcga gaacgcgctc atcgcggtga
     2461 acacattgcc cggcgccatc gccgcccacg gccagaacag cgcgccgagg gccagcgcga
     2521 tcgccgccgc cggcagcagc gcgagtacgc cgcgcaggag gaagcgcagg cgcccgtgcg
     2581 cctgcagggc cgcagccgcg agcatgccga cgccgaggta gaaaaccgca aacaccgctc
     2641 cgatgcgcag cccgaaggcg cagccgagcg cgacgcccag ccccgccagt acgcgccagg
     2701 gcggcgcggg cagggtgtcg agcacgcgca cgctgaagta cagggcccac agcatcgtgg
     2761 tggcgaaggg gatgtccttg gtgtgggtga acatcgcccc cgaccacgaa ccggtgatca
     2821 gcagcagcac gagcgccgcc agccccgccc actcgccggc cagccgacgc gcgagcagcc
     2881 aggtaccggc cagcccgaga aggccgaagc cggccgagat caggtggcgc aggtcccaca
     2941 gcgccggccc ctcggccgcg ccggcgcgct ccagggcagc cgcgacgagg tcgaagaagc
     3001 cgccatacag atagaggttc ttgtattcga aggcctggcg gtcggcaaac cccgacaggt
     3061 agaagtcgag cagcaggcgg ccgtagacat gctggacctc ctcgtcgttg ctgatgccgt
     3121 gccggtcgaa ggtgagcagc acgaacatcc cggccagcgc cagcacggcg agcgcgatcc
     3181 ggcgtgcgag cgcgccatgc gttgcggcct caagggtcac ggccggtgcc tcccccgccg
     3241 cggccggcgc ccgcgccgcc gcgcgcggcg ggatcatcga tcgcgctccg gcctgcgctc
     3301 gaagccgagc cgctccgaaa ccagaaacag cggacggccc ttcacctcgg tgaagatccg
     3361 ccccacgtac tcgccgagca cgccgaggct gatgagctgg atcccggaca ggaacagccc
     3421 cgacaccatc agcgacacgt agcccggcag gtcgatgccg aacagcatcg tgcgcagcac
     3481 gagaaacacg ccgtacaggc cggacagccc cgccatcatc aggccgatca ccgaccacac
     3541 ccgcagcggc agggtgctga aggcggacag cccgtcgatc gcgtagcgca gcaggcgcag
     3601 catcgaccat ccggacacac cgccggcgcg ctgcgcgggc tcgaactcga cgacctcctg
     3661 gcggaagccc acccagctcg tgatgccctt catgaagcgg gtgcgctcgg gcaggctgtt
     3721 gatcgcatcg accaccgcac ggtcgaacac acgaaagtcg ccgccgccct cggcgagctc
     3781 gacctcggag accttgctga agaaggcgta gaaaccgcgg gtgagcttgc gtcgcagcca
     3841 ggggtcggtg acgcgcgagc gccgcaccgc ggtcaccatc atcgcgccgc cgcgccagcg
     3901 cgcgagcatc tcggggatca gctcgggcgg atgctgcagg tcgccgtcca tcagcacgat
     3961 cacgtcgccc gtcgccgcct ggaggccagc ggccatcgcg gcttccttgc cgaagttgcg
     4021 cgcgaagcgg atcgccttga ggtggcggtc accggcgcac aacgtggcga cgcgcgcata
     4081 cgtgtcgtcg cggctaccgt cgtccacgca gacaatgtcc cagcccgaca gctccaggcc
     4141 cgcgagcacc tgcgacaggc gccgatgcag cgcctccacc gtttcgccct cgttgtagac
     4201 cgggaccacg accgagagtc gggggtgtgc cgaggaggcg ggcggcacat gggggtgggc
     4261 gtcgagcgag tcggagtgcg acacgatgaa actaccggcg agtgggctcc gcagccggag
     4321 cgaaggcgtg cacgataaac cattcgtgcc ctgcccggcg tgccccgcgc gggccagggt
     4381 gcgcgatact tcggactttc cgcccgcagc cccgatcgca tgcaagcccc ttcccgccct
     4441 ggcgcgccgg ccacccgtcc ggtggtggtg tgcgccgacg actacggcct cgcccccggg
     4501 gtcagcgagg cgatcgccgc actcgtcgcg accggccggc tgtcggccac cagctgcatg
     4561 agcgcgctgc ccgactggca ccgcgctgcg ccccccctgc gcgcactgat ggcaagcgcg
     4621 ccggccgacg tcggcctgca cctgaccctg accgaccagc ccccgctcag cgccgcggcg
     4681 cgccgggcct ggggcgagcg cctgcccccg ctcggccgcc tgctcgccgc cgccctcgcc
     4741 cgccgcctgc cggcgcaggc cgtggcggac gagatccgcg cccagctcga cgccttcgag
     4801 gacgcctggg gggacgcgcc cgaccacgtc gacggccacc agcacgtgca tgtgctgccc
     4861 ggcgtgcgcg agcgcctcgt cgccgagctg ctgcgccgcc acccgcgcgg ccgcgtgtgg
     4921 gtgcgcgact gcgtcgagcc gccgctgcgc agcctgcagc ggcgggaggc ggcgggcaag
     4981 gcctggttca tctccgccct cgcgcgcgga ctgcaccgcc agttgcgcga ggccggcctg
     5041 ccctgcaacg agggcttcag cggcctgcac gacttctccg tcgagcgtcc cttcgcagcg
     5101 aagatgcgcc gcttcctcgc cggcaccggc ccacgcccgc tggtgcatgt gcatcccggc
     5161 cgggtggacg ccgccctgcg cgcctgcgat ccgctgacca ccccgcgcga ggccgagctc
     5221 gcctacctcg cctccgccga atacctcgcc gatctcgccg ctgccggcct gcgccctgct
     5281 cgcttcgcag cgttcgatgc ccccgaggtc gggacgaccg ctccgtcctg ctagcgcgat
     5341 gcggcgcggc cggggctgcg gctacggacg cgcccgcgca gcatcccttg gcgcaagatt
     5401 cggcctgacg ggtcggtagc cacgcatgtg gcacgcgcga attgcacaag cgtccgcccg
     5461 gtcgatagga tccccgccat gcagccgtcc atcccttccc ccgaccccga tgcgggtctc
     5521 ctcgccagcc cctgcgcaaa cccctacgtc ggccgcttcg ccccctcgcc cagcggcgcg
     5581 ctgcacttcg gctcgctggt cgccgccgtg ggcagcttcc tggatgcgcg cgcgcacggc
     5641 ggacgctggc tgctgcgcat cgaggacgtg gacaccccgc gcacggtgcc cggcgccgcc
     5701 gcaggcatcc tcgccacgct ggaacgcttc ggcttcgaat gggacggcgc gatcgtgcgc
     5761 cagagcgaac gcggcgaagc ctatgcggcc gcgctcgagc gcctgcgcgc ggccggcctc
     5821 gcctatccct gtgcgtgcac ccggcgcgag ctcgccggcc agccgctcgc gcgcgacggc
     5881 tcgcgccgct atcccggcac ctgccgcgac ggcctgccgc cgggacggac cggccgcgcc
     5941 tggcgggtgc gcgccgaggg cgtggtgcgc ttttgcgacg cggtgcaggg cgagcaggag
     6001 atcgacctcg ccgccgacgc cggcgactac gtggtcaagc gcgccgacgg cctcttcgcc
     6061 tatcagctcg cggtggtggt ggacgacgcc gaagcggggg tgacccacgt cgtgcgcggc
     6121 gccgacctgc tcgactcgac cgcgcgccag atccacctcc tcggcctgct cggtcatccg
     6181 gtgcccgcct acgcccacct gccgctggcc accaaccccg cgggcgagaa gctctccaag
     6241 cagacgctgg cgcgcgcgat cgacgagcat ccgccgcagg ccgccttgct ggccgcgctg
     6301 cgctttctcg gccacaatcc acccgacatg ctcaccgccg cgccgctcgt cgaaacgtgg
     6361 gcgtgggcgc gcgcccactg gtcgctcgcc gccgtgccgc gccgccgcca ggccgtggcc
     6421 gacggcttct tttgaggaaa ctccatgcac ccgaacgaca tcagcaccca gcccgaagcc
     6481 atccgcagcc tgctgcagca ggcgcgcacg atcgccgtgg tcggcatctc ggccaggcac
     6541 gaccgcccca gccacgaggt cgcgcactac ctgcagcgtg ccggctacac catcatcccg
     6601 gtcaacccgg cctacgagga ggtgctgggg cagaagtgct accccaacct gcacgaggtg
     6661 ccggtaaaga tcgacctcgt cgacgtgttc cgcaagccgg cggaagtgat ggcggtggtg
     6721 gacgaggcca tcgccgtggg cgccggcagt gtgtggctgc agctcggggt gatcgcgccc
     6781 gacgccgcgg acaaggccgc cgccgccggg ttgaaggtgg tgagcgaccg ctgcaccaag
     6841 atcgagcacc gccgcctgat cggctgaaac cgtggatgcg gcgcatggaa tacgcgccgg
     6901 cgccgctcga gcgcattatt cgcaccttcc ggcgctcccg cagaaaccat cgcaaccgcc
     6961 tgtaggagcg gcggcagccg cgaatccggc gcatggaata cgcgccgacg ccgctccagc
     7021 gcactattcg cgccttccgg cgctcctaca agaaccctcg cacccccgta ggagcggcgg
     7081 cagccgcgaa ttcggcgcgg cccggcccga ctcggcccgc gttgcccgcg tcggcgcagg
     7141 ggtcggcatc ggcgtggtgt cagtgcgcnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7261 nnnnnnnncc gacggtggcc cattggtggt cgatcaccgc caccttggcg tgcaggtggc
     7321 tgcggtggta ctcgaacagg cggatgccgg cgtcgaggaa gatcggatac agcgcgcgcg
     7381 tcgcatacac ctgcatcggg tggtccgaca cgccctgcag cagcagagtc acccgcacgc
     7441 cgcgccgggc ggcatcgatc agcgcctggc ggaaacgccg acccgggaag aagtaggcgt
     7501 tggcgagcac gatctcctcg cgcgcgccgg cgatcgcctc gaggtaggcc tcctcgatgg
     7561 cgtggcggtg gcgcaggttg tcgcgcacca cgaaggtggc gcggatcgag cccgcggcct
     7621 cggtgcgcgg cggcgccagc agcggctgcg cggcgcgcct gcgaaagctc gcccacgcca
     7681 ccagccgcca cagccgctgc gccgaggcca ccacgggcgc gagcaccggc ccctcgacgc
     7741 gcaccgcgta gtcgtagcgc gggttcgcca gcgcgccggc gtcgaagtcg tccaccacgt
     7801 tgatgccacc gacgaaggcc acgcggccgt cgatcgccac caccttgcgg tgcagccggc
     7861 gcaggcggtg gcggcgcagc gagagcgggc gcagctcgcg gcggtagatc agcacctgca
     7921 cgccggcctc gcgcaggcgc ggcatcagcg tggggacgaa gttgcgcccg ccgaagccgt
     7981 ccaccatcac ccgcaccgcc accccgcgcc ctgccgcgcg cgcgagcgcc gcggcgatgc
     8041 gcgcgccggt gccgtcgtcc tcgaagatgt agctctgcag gaagatctcg cgctcggcac
     8101 ggtcgatctc ggcttccagc gccgggaagt actgcccgcc gttctccagc aacgcgaccg
     8161 cgttgcccgc gatgaactgc atcagccgat gggctccagg tcggcggtca gcgccgcgtg
     8221 gtcggagatc tgcgcccacg gcgcgccgta atgcacctgc gcctggcgca cgcggaagcc
     8281 gcgcacgtag atgcggtcga ggcggaagaa gggcagcgtg ctcggatagc tgcgcgccgg
     8341 ccgcccgcgt ccgctgccga aggcctcggc aagcccgagc cggcgcccga gcaggtcgtc
     8401 ggcgcggttg cgccagtcgt tgaagtcgcc ggcgatgatc agcggcgcgt tgcccggggc
     8461 gagctcctcc atgcgctcgg cgagcgcctc catctggcgc cgccggctgc ccgccatcag
     8521 tcccagatgc acgcacacgc aatgcaccgg cacgtcgaac tcgggcagcc gcacctcaca
     8581 gtgaagcagg ccgcggcgct cgaagcgatg gtcggagacg tcctggttgg cggtgctgag
     8641 gatgaggtgg cggctgagga tggcgttgcc gtgatggccg tggtcgtaga tcgcgttgcc
     8701 gccatacgcg atctcctgcc aggcgtcctc ggcgaggaac tcgtgctgcg gcagcgcggg
     8761 ccagtcggga tggcgagccg gatgacgcag gtgcagtccc tgcacctcct gcaggaagac
     8821 gaggtcggca tccaggctgc gcaggcggtc gcgcagctca tgcaccacca tgcggcggtt
     8881 gaactgcgag aagcccttgt ggatgttgta gctgcagatc ctcagcgcca tggccgtcgg
     8941 acctcgtgtg cgtcggtcag gagacggcca gcatgcggtc gagcgcgatg cgggcgagct
     9001 cggcctcgtg cgcggggacc ttgatctggt tcaccacctt gccctcggcg aggttctcca
     9061 gcgtccacgc caggtgctgc gggtcgatgc gctgcatggt cgagcacatg cacacggtcg
     9121 gcgccatgaa ctgcaccacc ttgccctgcg gcttcatctc ctcggccagg cggctcacca
     9181 ggttgagctc ggtgcccacc agccagtggg tgttgggcgg cgcctgggtg atggtgttga
     9241 ggatgaattc ggtggagccg acgtagtcgg acttctggca cacctcgagc atgctctcgg
     9301 ggtgggagat cacgaagccg tgcgggtgct tctcgcgcca gcggtcgata tgcaccggct
     9361 ggaacatctg gtgcaccgag cagtgtccct tccaaagcag gatcttcgcc ttgcggatct
     9421 gctcggcggt gaggccgccg tactcgaggt cggggtccca caccaccatc tcgtcgagcg
     9481 ggatgccctt cttgaagccg gtccagcgcc cgaggtgctg gtcggggaag aacagcacct
     9541 tctcgcgctt ggcgaacgcc cagtcgagga tggtcggggc gttggtcgag gtgcacacga
     9601 tgccgccgtg ctcgccgcag aaggccttga gatcggccgc cgagttgatg taggtcaccg
     9661 gcgtgatgat ttcgtcgggc ttgtcgagca cctcggcgag ctcgcgccag cagcgctcga
     9721 ccttggccag gctcgccatg tcggccatcg agcagccggc ggcgaggtcg ggcaggatgg
     9781 cgatctggct gggcttggac aggatgtcgg cgacctcggc catgaagtgc acgccgcaga
     9841 acacgatgaa ctcggcgtcg gtctgcgagg ccaggcgggc gagcttgagc gagtcgccgg
     9901 tgaggtcggc gtgctgatag acgtcggcgc gctggtagtg gtggcagagc agcaccgccc
     9961 gctcgccgag gcgtgcacgg gcggcgcgga tgcgctcctg cgcctcgttg tcggcgagca
    10021 cgttgaagcg gtcgaagctg atggtggaga cttgcattgt ttcggtatcc ggatccgtgg
    10081 gagggggcaa tcccggggtt acgggcatcg gaccccgcgt gcggccgcag gttcgaccgc
    10141 ggcaggcggg gccgggtaag gatttgttgc cgctcagccc tggtaccagg gcaggccggc
    10201 gaggcgccag ccgccgatgc ggttgcgctg gttgttggcg tccttgtcgc cttcgaagcc
    10261 ttccagcacg ttgtagcagt tggcgtagcc gttggcgctg gcgagccgcg ccgcggagtc
    10321 ggagcgcacg gcggaacggc acaggaacag caccagcgcc tcgggatcca cctgatgctt
    10381 cagctgggcg aggaagttcg ggttctcctg catcgaggga tagctcttcc actcgatctc
    10441 gatcgcgccg ggcacgcgcc ccacccagtc gagctcggcg cgcgtgcgca catcgaccag
    10501 cttggcaccg ggggcgagct gcatcacctg ccaggtttcg gcgggggtga gcgcgccctg
    10561 gtagggcagc ccgaggcttt cggcgcgctc gtgggcgagc gtcaacagtt ccgacagggt
    10621 tcccatgcgc acatccgtct aaaatgaaag cggtcgaagt atagcgcgtc cgccgcgccc
    10681 ccctcatgcc ctcccgccaa gcccattccc cggtcccggc cgcccctgcg gccacggacg
    10741 aactcgcccg cagccgcggc atccagcgcg ccaccctggt ggcgatcctg accaactcgc
    10801 tgctcaccat cggccaggtg gtcatcggcc tgttcgccgg cgccttcagc ctcgtggccg
    10861 acgcggccca caccctgtcc gacctggtca ccgacctgct ggtcctgctc gccggccgtc
    10921 acagcgccga tccggccgat accaaccacc cctacggcca cggccgcatc gagaccgtca
    10981 ccaccctggt gctgggggcg gtgctggggg cggtgggcgt cggcttcctg tggagctcgg
    11041 ggatccgcct gcaggacatc gaggccttgc cggtgctgca cccggcggcc ctggtcatgg
    11101 cgctgctgac cctcgccgcc aaggagggcc tgttccgcta cacgctggcc gccgcacgcc
    11161 ggctcaacgc ccccatgctc gaggccaacg cctggcatgc acgctccgac gctgcgtcat
    11221 cgctggtggt ggccgccggc atcggcggca gcctggccgg ctaccccttc ctcgagccgc
    11281 tcgctgcggc cgtggtcggc ttcctgatcc tgcacatggg cctgcgcctg gcgtggaaat
    11341 cgatcggcga gctgatcgac accggtctgc cggaggaaga gctcgagcgc ctgcgcgcga
    11401 cgatccgcga gaccccgggc gtgatcgggc tgcacgacat gcgcacccgg cggatggccg
    11461 atcgcgtgct gtgcgacgcc cacgtccagg tcgacccgcg gctgaccgtc tccgagggcc
    11521 accgcgtctc ggacgcggta tacctgcgcg tacgcgccgc ccaccccgag gtgcgcgacg
    11581 tgctggtgca catcgacccc gaggacgacg gcgagctgca ggtcgtcccc cccggcccgc
    11641 tccccgagcg cgtcgagatc ctcgcgcgca tgcgcgagct ccttggcccc gcgttcgccg
    11701 agccccggcg ggttcagatc cactacctcg gccagcgcgt ggaggtggag atcatcctgc
    11761 cctcggcccc cgcggccgaa gcgctcgaga tgctgcaatc gcggcgcaag gcgtggctcg
    11821 cggagcatcc ccattaccgc aacatccgcg tcttcgtgga gacagcacca taacagtgca
    11881 ttacgcgacc aacgacgcac cactctggtg cattgaagtc ggaccggagc accgatttcg
    11941 ggctcgcgcc cttgtggcac aatgccctgc gcgctgaaac cgggctggca cgctaagtgc
    12001 ttagccctgc tcacacgaat ccggcgcatc gaccccaggc cgctgcacca cccgctcaac
    12061 gcaacaacgc ctcatctcac caggagtgaa aatgaacgcc caagacgtca tgaagatgat
    12121 ccaggaaaac gaagtgcgct tcgtggacct gcgcttcacg gatattcgcg gcaaggagca
    12181 ccacgtcggc ctgccggtgt cggccttcga ggaagagcac ttcgagcacg gccacccctt
    12241 cgacggctcc tcgctggcgg gctggaaggg catccaggcc tcggacatga tcctcatgcc
    12301 ggagccctcg accgcctaca tcgacccctt cttcgacgag accacgctgg tcatcacctg
    12361 cgacgtcatc gagccctccg acggcaaggg ctacgatcgc gatccgcgct cgatcgccaa
    12421 gcgcgccgag gcctacctga agagcaccgg tatcggcgac accgccttct tcggccccga
    12481 gcccgaattc ttcatcttcg actcggtcga gtggtcggtc gacatgtcgg gcgtgtatag
    12541 caagatcatc tcggaagagg ccgcctggtc cactgccgac aagttcgaag gcggcaacac
    12601 cggccaccgt ccgcgcgtca agg
//
LOCUS       DAOTIN010000090        12415 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_6065_length_12415_cov_9.109871, whole genome shotgun sequence.
ACCESSION   DAOTIN010000090 DAOTIN010000000
VERSION     DAOTIN010000090.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 12415)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 12415)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12415
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6065_length_12415_cov_9.109871"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..376)
                     /locus_tag="P5537_12400"
     CDS             complement(<1..376)
                     /locus_tag="P5537_12400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HRV78882.1"
                     /translation="MLRIITLNLNGIRSACTKGLLDWLPAQQADFLCVQELKAQDADL
                     RPEMRAPAGMRGWFHAAEKKGYSGVGIYSRHTPDRVVEGLGIPAIDAEGRFLQLDFGK
                     LSVVSLYLPSGSSSEERQQVKFD"
     gene            416..1060
                     /gene="pyrE"
                     /locus_tag="P5537_12405"
     CDS             416..1060
                     /gene="pyrE"
                     /locus_tag="P5537_12405"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004343674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HRV78883.1"
                     /translation="MDFSRDFIALACRKGVLRFGAFVTKAGRNSPYFFNAGLFDDGAS
                     FRELCGYYARTIRASGIACDMLFGPAYKGIPLVAGTAIRLAEDGVDLPFAFNRKEAKD
                     HGEGGTLIGAPLRGKVLILDDVISAGTSVRESVELIRAAGAEPAGVVIALDRMERGKS
                     ALSAVEEVKENFAIPVVAVATLEDLIAYLADSPELAANLGAVQAYREQYGISSR"
     gene            1041..1715
                     /locus_tag="P5537_12410"
     CDS             1041..1715
                     /locus_tag="P5537_12410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78884.1"
                     /translation="MGFPRAERVLAGFSWVFALAVSSGTLAAQPAGAASIYCCDVGGQ
                     PVCGDILPAACYGRAYREMSPSGIVRRSVPAPLTADEIAQRAAAEHKRRAEEAERMRQ
                     LRLDQALLETYRSVQDLDSRRDRELRDLDRSIRELRARESELIERQHGLIEEATRTER
                     SDVASSLEADIRLLDSEIAAQSSVVAAKLRERSAVVERFEEHRRRYVELTSAPESARI
                     PPMPRR"
     gene            1768..3846
                     /locus_tag="P5537_12415"
     CDS             1768..3846
                     /locus_tag="P5537_12415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin oxidoreductase family protein"
                     /protein_id="HRV78885.1"
                     /translation="MPPSIPTEVRVRAACPHDCPDTCAMEVTVADGRAVKVRGAADMP
                     FTNGALCTKVAHYLERVYSGRRLLHPMKRVGRKGEGRFARISWDEALDTIAAKYRDIA
                     AEDPRAILPYSYCGTMGLVQGESLDRRFFHRLGASLLERTICATAGAHGWRATVGAML
                     GADPEAATEARLILIWGANPVVSNLHGWRHLQEAKRRGARLVCIDPRRTDTAKKCDLH
                     LAPLPGTDGALALAMMQVLIAEGLLDREYIARHSLGFDELAARVRTCTPEWAAPLTGL
                     AAAAIRSLAIEYGRSARSLIRLNYGLNRCAGGGMAVRNVACLPALTGAWRHPGCGALL
                     STSGNFPVDAQALARPDLYPDAKRFPPRALNMSFIGDVLLDTRDPPVRAIHVYNANPV
                     AVAPDSHRVRAGFAREDLFCVVHEQFQTDTADYADILLPATSQLEHRDVHKAYGHFYV
                     VDNRPAIAPLGEARSNTAVFRALAQRLGFAAAALYESDDAIAAVAFRADDPRVAGLAE
                     GLRTQGWARLALPAGYAPFADGGFRTPSGKCEFFSAALAREGLDPLPAWHPPAESVPS
                     NPALAARYPLALITPPARNFLNSTFANQARFLAEEGGPKLEIHPEDAAARGIADGARL
                     RIRNDRGDFVAHAVVTTDVRPGVVCSPSVWWPKLCEGGHNANAVIAARPTDMGGGPTF
                     YDCLVEVEPA"
     gene            3843..4634
                     /locus_tag="P5537_12420"
     CDS             3843..4634
                     /locus_tag="P5537_12420"
                     /EC_number="2.3.1.286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004375689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0017136 - NAD-dependent histone
                     deacetylase activity [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent deacylase"
                     /protein_id="HRV78886.1"
                     /translation="MSVDKTLAAVADVLARAQRILFVTGAGISVDSGLPTYRGIGGLY
                     HDRLTEEGLTIEEALSGEMMATRPEIAWRYIAQIESSCRGAQPNAAHRLIAALEQEKA
                     LVCVLTQNVDGLHRAAGSRNVIEIHGTVHRLHCMSCRQGRRVEDYAGLSIPPECPRCG
                     GILRPDVVLFGEALPELAIERLESVLSQGMDAVVSIGTTSVFPYIAGPVLWAARQGVP
                     TIEINPGDTTVSAIVDHRLRMCAAEALPALWQRMHPAEPAEDRPL"
     assembly_gap    4760..4859
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(5095..8988)
                     /locus_tag="P5537_12425"
     CDS             complement(5095..8988)
                     /locus_tag="P5537_12425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004343670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/FMN-binding oxidoreductase"
                     /protein_id="HRV78887.1"
                     /translation="MSQRLREIPYNYTSFSDREIVIRLLGAEAWAVLDQLRTERVTGR
                     SARMLYEVLGDIWVVRRNPYLEDDLLTSRERRDALIGALDHRLNEIDKRRQGNDRVTL
                     LVARAREAVSNFERWFDDTARRRKAVLKALAKHTRRDNVCFDGHARVSHVTDATDWRV
                     EYPFVVLYPDTEEEMAPLVRECIALGLTIIPRGGGTGYTGGAVPLDASSVVINTEKLL
                     AMSAVEPTVLPGVDGPMAEPYPTIRTGAGVVTERVSEAAALAGRVFAVDPTSASASCV
                     GGNIAMNAGGKKAVLWGTALDNLAWWKMVTPDGNWLEVERLDHNFGKIHEQETVRFRL
                     RRFDGLTNAALGEEILAMPGAACRKVGLGKDVTDKFLGGVPGVQKEGTDGLIVAARWV
                     LHKMPPVTRTVCLEFFGQVREAVPAIVEITDFFKPGGAGHAAGVQLAGLEHLDERYVK
                     AVGYATKARRHGRPKMVLIGDIVGHDEDAVMKAASEVVRMTNARGSEGFIAVSPEQRK
                     RFWLERSRTAAISRHTNAFKINEDVVIPLPRMGEYCDGIERINIELSLQNKIALCDRL
                     AEFLQGELPLDVKDEGLDREALISDHRAQALEQVAGVRRRWQWLLDNLDLALAEAEPQ
                     FAAYGVQAGELSNRAASPTLFHRLQDYSIRVSWKEELRPLLEQTFDGALFARILVRVA
                     EIHREVLRGRVFVALHMHAGDGNVHTNLPVNSDHYEMLQTANRAVDRIMALARSLDGV
                     ISGEHGIGITKLDYLTDDEMANFWAYKEKVDPEGRFNRGKLMRKGPVRGNLDNAYTPS
                     FNLMGHESLIMEQTDVGDIAHDIKDCLRCGKCKPVCSTHVPRANLLYSPRNKILSTSL
                     LIEAFLYEEQTRRGVSLAHWAEFEDVADHCTICHKCEKPCPVDIDFGDVSIKMRNLLR
                     KQGKKSFNPGKAAAMAFLTIKDPTTIKAIRTGMIDWGYKAQRFGYEMGRKFGLIQPQV
                     KAPPATLGKAPLISPTVRAQVIHFINKPMPGNLPKKTSRALLDIEDDKVIPVIRDPQK
                     ANGESEAVFYFPGCGSERLFSQVGLATQAMLYHVGAQTVLPPGYLCCGYPQTAAGEED
                     KGQKITTDNRVLFHRVANTLNYLDIKTVIVSCGTCMDQLQKYEFEKIFPGCRLLDIHE
                     YLMEKGVRLEGVGGVKYMYHEPCHTPMKQYQGIKVANELMGTRVDLSDRCCGESGTLA
                     VARPDISTQVRFRKQEEIEKGAAALREGDASVKVKMLTSCPSCLQGMHRYANDAGGIE
                     PDYIVVELAKHLLGESWLPDYVAKANSGGIERVLL"
     gene            complement(9115..9465)
                     /locus_tag="P5537_12430"
     CDS             complement(9115..9465)
                     /locus_tag="P5537_12430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HRV78888.1"
                     /translation="MSAIERHGVTARYADAVIHAGIIHLVEVPASSAGPIETQTREVL
                     ESIGRQLARLGSDPARILMATIYLVDMADYAGMNTVWDAWVPPGSAPVRACVQVAGLA
                     DPGWRIEIALTAAR"
     gene            complement(9546..9959)
                     /locus_tag="P5537_12435"
     CDS             complement(9546..9959)
                     /locus_tag="P5537_12435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqaA family protein"
                     /protein_id="HRV78889.1"
                     /translation="MLSGELAPLAGLAASAFLAATLLPGGSEAVFAALLTLRPELTPA
                     ALLVATVANTAGGMSTYALGRLLPRKEPGAHARTLQRWGSLALLLSWVPLIGDALCAA
                     AGALRLNAFACLAWMALGKGLRYAAIAWALPSAGA"
     gene            10086..10547
                     /locus_tag="P5537_12440"
     CDS             10086..10547
                     /locus_tag="P5537_12440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PsiF family protein"
                     /protein_id="HRV78890.1"
                     /translation="MKRILGAGCAVLVLAALAPAQAWANPQHERMKRCNAEAKEQALK
                     GEARKAFMGTCLRGKHDAAAPAAAPGAPVAAAAAAAVPAQAGAGAPAQAAAPAPAAVA
                     PAVAAPAVAAESVQKVSSEDKARQKACNRAATEQSLRGAKRKAFIGECMSG"
     gene            complement(10628..11500)
                     /locus_tag="P5537_12445"
     CDS             complement(10628..11500)
                     /locus_tag="P5537_12445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004327335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FHA domain-containing protein"
                     /protein_id="HRV78891.1"
                     /translation="MSERKNLCVLVALHPVDAVLAERLGADEARHAAERHARRIERAV
                     VMQGGQVLIDDAEQTVAAFERGDAAVHAASEALERIHALPPLLGSKQTVRIGVHYGAL
                     EGSAEEPVGDGPAVARQLAHLAESGQALISGTAVMLLGGAARQLVGSQPLSGPVWTRI
                     GIPVHAIGQRSGLVTSVPGATRLSSRLRLRHQQEVVFVEELRPVLLLGRELANDITIM
                     DPRASRQHARIERRPEGFVLFDQSTNGSFVAIEGKPECFVRQESMLLDGPGRLGCGFS
                     TTEVERDLVFFDIV"
     gene            complement(11620..>12415)
                     /gene="ttcA"
                     /locus_tag="P5537_12450"
     CDS             complement(11620..>12415)
                     /gene="ttcA"
                     /locus_tag="P5537_12450"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004384785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HRV78892.1"
                     /translation="MVCVSGGKDSYTLLSCLLALRERAPVDFRIVAMNLDQKQPGFPD
                     HVLPAYFESIGVEYRIVTEDTYSIVKDKIPEGKTTCSLCSRLRRGIIYRTAAELGATR
                     IALGHHRDDMLETLFLNMFFGGKIKAMPPKLVSDDGKHVVIRPLAYCTEADIARFART
                     MDFPIIPCNLCGSQENAQRKLIKNMLQGWARDYPGRIESLATALKNVVPSHLADQRLF
                     DFVGLTQNTVVEEGDTAFDPPELPDRTLGASVTLFRAGDQEERECA"
BASE COUNT         1770 a         4305 c         4350 g         1890 t
ORIGIN      
        1 agtcgaactt cacctgctgg cgctcctccg agctcgagcc cgagggcagg tagagcgaca
       61 ccaccgagag cttgccgaag tcgagttgca ggaagcggcc ctcggcgtcg atcgcgggga
      121 tgccgaggcc ctcgacgacg cggtccggcg tgtgccgact gtagatgccc acgccgctgt
      181 agcccttctt ctcggcggcg tggaaccagc cccgcatgcc cgcgggcgcg cgcatctcgg
      241 ggcgcaggtc ggcgtcctgc gccttgagct cctgtacgca caggaagtcg gcctgctgcg
      301 cgggcagcca gtcgagcagg cccttggtgc aggcggagcg gatcccgttg aggttcaggg
      361 tgatgatgcg taacatcggc ggtttccagt ttcgctgcca ggcagccaaa aaaccgtgga
      421 ttttagccgg gatttcatcg ccctcgcgtg tcgcaagggt gtgctgcgct tcggcgcctt
      481 cgtcaccaag gcgggacgca actcgccgta tttcttcaac gccggcctgt tcgacgacgg
      541 cgcctcgttc cgcgagctgt gcggctacta cgcgcgcacg atccgcgcct cgggcatcgc
      601 ctgcgacatg ctcttcggcc cggcctacaa gggcatccca ctcgtcgccg gcacggcgat
      661 ccggctcgcc gaggacggcg tggacctgcc cttcgcgttc aaccgcaagg aggccaagga
      721 ccacggcgag ggcggcacgc tgatcggcgc gccgctgcgc ggcaaggtgc tgatcctcga
      781 cgacgtgatc tcggccggta cctcggtgcg tgaatccgtc gagctgatcc gtgccgccgg
      841 cgccgaaccc gccggcgtgg tgatcgcgct cgatcgcatg gaacgcggta aaagtgcctt
      901 gtccgcggtc gaggaggtca aggagaattt cgccattccg gtcgtcgcgg tggccacgct
      961 cgaagacctc atcgcctacc tggcggacag tcccgaactc gcggccaatc tcggcgccgt
     1021 ccaggcctat cgggaacagt atgggatttc ctcgcgctga acgcgtcctc gccggtttca
     1081 gttgggtatt cgcgctggcg gtatcttccg gcacgctggc ggcgcagccg gcgggtgccg
     1141 cctcgatcta ttgctgcgac gtcggtggcc agccggtgtg cggcgacatc ctgcccgccg
     1201 cctgctacgg gcgcgcctac cgcgagatga gtccctcggg catcgtgcgc cgctccgtgc
     1261 ctgcgccgct caccgccgac gagatcgccc agcgcgcggc cgccgaacac aagcgtcgcg
     1321 ccgaggaggc cgagcgcatg cgccagctgc gtctcgacca agccctgctc gagacctatc
     1381 gcagcgtgca ggatctcgac agccggcgcg accgcgagct ccgcgatctg gaccgcagca
     1441 tccgcgagtt gcgcgcgcgc gagtccgagc tcatcgagcg tcaacacggg ctgatcgaag
     1501 aggccacgcg cacggagcgc agcgatgtcg cctccagcct ggaggccgac atccgtctgc
     1561 tcgacagcga gatcgccgcg cagtcctccg tggtcgcggc caagctgcgc gagcgcagcg
     1621 cggtggtcga gcgcttcgag gagcaccgtc gccgctacgt cgagctcacc tcggcgcccg
     1681 agtccgcgcg catcccgccg atgccgcggc gttgagtctt tcgccgtgcg gcccggccgg
     1741 gccggacggc cgcaacacga ggccgcgatg cccccgtcga tccccaccga agtccgcgtg
     1801 cgtgcggcct gcccgcacga ctgccccgac acctgcgcga tggaggtcac ggtcgccgac
     1861 ggccgcgcgg tgaaggtccg cggcgcggcc gacatgccct tcaccaacgg cgcgctgtgc
     1921 accaaggtcg cccactacct cgagcgcgtg tattccgggc gccgcctgct gcatccgatg
     1981 aagcgggtgg ggcgcaaggg cgagggccgc ttcgcgcgca tctcctggga cgaggcgctc
     2041 gacaccatcg cggcgaaata ccgcgacatc gccgccgagg acccgcgcgc gatcctgccc
     2101 tacagctact gcggcaccat gggcctggtg cagggcgaga gcctggatcg gcgcttcttc
     2161 caccgcctcg gcgcgtccct gctcgaacgc acgatctgcg ccaccgccgg cgcgcacggc
     2221 tggagggcca ccgtgggcgc catgctcggc gccgaccccg aggccgccac cgaggcccgc
     2281 ctgatcctca tctggggcgc caacccggtg gtctccaacc tgcacggctg gcgccacctg
     2341 caggaggcga agcggcgcgg cgcccgcctg gtgtgcatcg acccgcgccg caccgacacc
     2401 gcgaagaagt gcgacctgca cctcgccccg ctgcccggca ccgacggcgc gctcgcgctc
     2461 gcgatgatgc aggtgctgat cgccgagggc ctgctcgatc gcgagtacat cgcccgccac
     2521 tccctgggct tcgacgagct cgccgcgcgc gtgcgcacct gcacgccgga gtgggcggcg
     2581 ccgctcaccg gcctcgccgc cgcggccatc cgcagcctcg ccatcgaata cgggcgcagc
     2641 gcgcgcagcc tgatccggct caactacggt ctcaaccgct gcgccggcgg cggcatggcg
     2701 gtgcgcaacg tcgcctgcct gcctgcgctc accggcgcct ggcggcatcc cggctgcggt
     2761 gcgctgctgt cgacctcggg caatttcccg gtggacgcgc aggcgctcgc ccgccccgac
     2821 ctctatcccg atgcgaagcg cttcccgccg cgcgcgctca acatgtcctt catcggcgac
     2881 gtgctcctcg acacccgcga cccgccggtg cgcgcgatcc acgtctacaa cgccaacccg
     2941 gtggcggtcg cgcccgacag ccatcgggtg cgcgccggct tcgcgcgcga ggacctcttc
     3001 tgcgtggtgc acgagcagtt ccagaccgac accgccgact acgccgacat cctgctgccc
     3061 gccaccagcc agctcgagca ccgcgacgtg cacaaggcct atggccattt ctacgtggtg
     3121 gataaccggc cggcgatcgc gccgctcggc gaggcgcgct ccaacaccgc ggtcttccgc
     3181 gcgctcgcgc agcgcctcgg ctttgcggcc gcggcgctct acgagagcga cgacgccatc
     3241 gcggcggtgg ccttccgcgc cgacgaccca cgcgtggcgg gcctcgccga gggcctgcgg
     3301 acgcagggct gggcgcggct cgcgctgccc gcggggtatg cgcccttcgc cgacggcggc
     3361 ttccgcacgc cctcgggcaa gtgcgagttc ttctccgccg cgctcgcgcg cgaaggcctc
     3421 gatcccttgc cggcctggca tccgcccgcc gaatcggtgc cgagcaatcc ggccctggcc
     3481 gcgcgctatc cgctcgcgct gatcaccccg ccggcgcgca acttcctcaa ctccaccttc
     3541 gccaaccagg cgcgcttcct cgccgaggag ggcggaccca agctcgagat ccatcccgag
     3601 gacgccgccg cgcgcggcat cgcggacggc gcgcggctgc gcatccgcaa cgaccgcggc
     3661 gacttcgtcg cgcatgcggt ggtgacgacc gacgtgcgcc ccggcgtggt gtgcagcccc
     3721 tcggtgtggt ggcccaagct gtgcgaaggc ggccacaacg ccaacgccgt catcgccgcg
     3781 cgccccaccg acatgggcgg cggtccgacc ttctacgact gcctggtgga ggtggagccg
     3841 gcatgagcgt ggacaagacc ctggcggcgg tcgcggacgt cctcgcgcgc gcgcagcgca
     3901 tcctcttcgt caccggcgcc ggcatctcgg tcgattccgg cctgcccacc taccgcggca
     3961 tcggcgggct ctaccacgac cgcctcaccg aagaggggct caccatcgag gaggccttgt
     4021 cgggcgagat gatggcgacc cggcccgaga tcgcctggcg ctacatcgcc cagatcgagt
     4081 cgagctgccg cggcgcgcag cccaacgccg cgcaccgcct gatcgccgcg ctcgagcagg
     4141 agaaggcgct ggtgtgcgtg ctcacccaga acgtcgacgg cctgcaccgc gccgccggct
     4201 cgcgcaacgt gatcgagatc cacggcaccg tgcatcgcct gcactgcatg tcctgccggc
     4261 aggggcgccg ggtggaggac tatgccggcc tctccatccc gcccgaatgc ccgcgctgcg
     4321 gcggcatcct gcgcccggac gtggtgctgt tcggcgaggc cttgcccgaa ctcgcgatcg
     4381 agcgcctgga gagcgtgctg tcgcaaggca tggatgcggt ggtgtcgatc ggcaccacca
     4441 gcgtcttccc ctacatcgcc ggcccggtgc tgtgggcggc gcgccagggc gtgcccacga
     4501 tcgagatcaa cccgggagac acaacggtga gcgcgatcgt cgaccaccgc ctgcgcatgt
     4561 gcgccgccga ggccctcccc gcgctgtggc agcggatgca tccggcggag ccggcggaag
     4621 accgtcccct gtagacgcgg aggaagccga gaacacggcg ctccggcaat cggtgggcag
     4681 tgccatcgga gcggccgctt tcgcgcctgc cggcgctcct acacgggcca tcacgcctcc
     4741 gcctcatgca ggagcgccgn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnc
     4861 ggcaggcgcg aacgacagcg tctccgcctc atgcaggagc gccggcaggc gcgagcggca
     4921 gcgctccgcc ccatgtagga gcgccggcag gcgcgaacga cagcgtctcc gcctcatgca
     4981 ggagcgccgg caggcgcgaa cgacagcgtc tccgcctcat gtaggagcgc cggcaggcgc
     5041 gaaccaaagc gcctccgtgt tcctggtgcg cggcaattcc ggatgattgc gcggttagag
     5101 caacacccgc tcgatccccc cgctgttcgc cttcgccacg tagtccggca gccagctctc
     5161 gccgagcagg tgcttggcca gctcgaccac gatgtagtcg ggctcgatgc cgccggcgtc
     5221 gttggcgtag cggtgcatgc cctgcaggca gctcgggcac gaggtcagca tcttcacctt
     5281 gacgctggcg tcgccctcgc gcaaggccgc cgcccccttc tcgatctctt cctgcttgcg
     5341 gaagcgcacc tgggtggaga tgtcggggcg cgccaccgcc agcgtgccgg actcgccgca
     5401 gcagcggtcg gacaggtcga cgcgcgtgcc catcagctcg ttggccacct tgatgccctg
     5461 gtactgcttc atcggcgtgt ggcagggctc gtggtacatg tacttcacgc cgccgacgcc
     5521 ctcgagcctg acgcccttct ccatcaggta ctcgtggatg tcgagcaggc ggcagccggg
     5581 gaagatcttc tcgaattcgt acttctgcag ctggtccatg caggtgccgc aggacacgat
     5641 caccgtcttg atgtcgaggt agttgagcgt gttggcgaca cggtggaaga gcacgcggtt
     5701 gtcggtggtg atcttctggc ccttgtcttc ctcgccggcg gcggtctgcg ggtagccgca
     5761 gcacaggtag cccggcggca gcacggtctg cgcgccgacg tggtagagca tggcctgggt
     5821 ggccagcccc acctggctga acaggcgctc cgagccgcag ccggggaagt agaacaccgc
     5881 ctcggactcg ccgttggcct tctgcgggtc gcggatcacc gggatgacct tgtcgtcctc
     5941 gatgtcgagc agcgcgcggc tggtcttctt gggcaggttg cccggcatgg gcttgttgat
     6001 gaagtggatc acctgcgccc gaacggttgg tgaaatgagc ggcgccttgc cgagcgtggc
     6061 cggcggcgcc ttcacctgcg gctggatgag gccgaacttc ctgcccatct cgtagccgaa
     6121 gcgctgcgcc ttgtagcccc agtcgatcat gccggtgcgg atggccttga tcgtggtcgg
     6181 gtccttgatg gtgaggaagg ccatcgccgc ggccttgccc gggttgaacg acttcttgcc
     6241 ctgcttgcgc agcaggttgc gcatcttgat cgacacgtcg ccgaagtcga tgtccaccgg
     6301 acagggcttc tcgcacttgt ggcagatcgt gcagtggtcg gccacgtcct cgaactcggc
     6361 ccagtgcgcg agcgacacgc cgcggcgggt ctgctcctcg tacaggaagg cctcgatcag
     6421 cagcgaggtg gacaggatct tgttgcgcgg ggagtacagc aggttggcgc gcggcacgtg
     6481 ggtcgagcac accggcttgc acttgccgca gcgcaggcag tccttgatgt cgtgcgcgat
     6541 gtcgccgacg tcggtctgct ccatgatgag cgactcgtgg cccatcaggt tgaagctggg
     6601 ggtgtaggcg ttgtcgaggt tgccgcgcac cggccccttg cgcatcagct tgccgcggtt
     6661 gaagcggcct tccgggtcga ccttttcctt gtaggcccag aagttcgcca tctcgtcgtc
     6721 ggtaagatag tcgagcttgg tgatgccgat gccgtgctcg cccgagatca cgccgtccag
     6781 gctgcgcgcc agcgccatga tgcgatcgac cgcgcggttg gcggtctgca gcatctcgta
     6841 gtggtcggag ttgaccggca ggttggtgtg cacgttgccg tcgccggcgt gcatgtgcag
     6901 ggcgacgaag acgcggccgc gcagcacctc gcggtggatc tcggcgacgc gcacgaggat
     6961 gcgtgcgaac agcgcgccgt cgaaggtctg ctcgagcagc gggcgcagct cctccttcca
     7021 cgacacccgg atcgagtagt cctgcaggcg gtggaacagg gtcgggctgg cggcgcggtt
     7081 ggagagctcg ccggcctgga cgccataggc ggcgaactgc ggctcggcct cggcgagggc
     7141 gaggtcgagg ttgtccagca gccactgcca gcgccggcgc acgccggcga cctgctcgag
     7201 cgcctgggcg cggtggtcgg agatcagcgc ctcgcggtcc aggccctcgt ccttgacgtc
     7261 gagcggcagc tcgccctgca ggaactcggc gaggcggtcg cagagcgcga tcttgttctg
     7321 cagcgagagc tcgatgttga tgcgctcgat gccgtcgcag tattcgccca tgcgcggcag
     7381 cgggatgacc acgtcctcgt tgatcttgaa ggcgttggtg tggcgcgaga tcgccgcggt
     7441 gcggctgcgc tcgagccaga agcgcttgcg ttgctcggga ctgaccgcga tgaagccctc
     7501 ggagccgcgt gcgttggtca tgcgcaccac ctcggaggcg gccttcatca ccgcgtcctc
     7561 gtcgtggccg acgatgtcgc cgatcagcac catcttgggg cggccgtggc ggcgcgcctt
     7621 ggtggcgtag ccgaccgcct tcacgtagcg ctcgtcgagg tgctccaggc cggcgagctg
     7681 cacgcccgcc gcgtggccgg cgccgcccgg cttgaagaag tcggtgatct cgacgatcgc
     7741 cggaaccgcc tcgcgcacct ggccgaagaa ctccaggcac accgtgcggg tgaccggcgg
     7801 catcttgtgc agcacccagc gcgcggccac gatgaggccg tcggtgcctt ccttctgcac
     7861 gcccggtacg ccgccgagga acttgtcggt gacgtccttg cccaggccga ccttgcggca
     7921 ggcggcgccc ggcatggcga ggatctcttc gccgagcgcg gcgttggtga gcccgtcgaa
     7981 gcggcgcagg cggaagcgga cggtctcctg ctcgtggatc ttgccgaagt tgtggtcgag
     8041 gcgctcgacc tcgagccagt tgccgtcggg cgtgaccatc ttccaccacg ccaggttgtc
     8101 gagcgcggtg ccccacagca cggccttctt gccgccggcg ttcatggcga tgttgccgcc
     8161 gacgcaggag gcgctcgccg aggtcgggtc gaccgcgaac acgcgcccgg cgagcgcggc
     8221 cgcttccgac acgcgctcgg tgaccacgcc ggcgccggtg cggatggtgg ggtagggctc
     8281 ggccatcggg ccgtcgacgc cgggcagcac ggtgggctcg accgcgctca tcgcgagcag
     8341 cttctcggtg ttgatcacca ccgagcttgc gtccagcggc acggcgccgc cggtgtagcc
     8401 ggtgccgccg ccgcgcggga tgatggtcag cccgagcgcg atgcactcgc gcaccagcgg
     8461 cgccatctct tcctcggtgt cggggtagag caccacgaag ggatactcga cccgccagtc
     8521 ggtggcgtcg gtgacgtggg agacgcgggc gtggccgtcg aagcagacgt tgtcgcggcg
     8581 ggtgtgcttc gccagtgcct tgagcaccgc cttgcgccgg cgcgcggtgt cgtcgaacca
     8641 gcgctcgaag ttcgacaccg cctcgcgcgc acgcgccacc agcagggtga cgcggtcgtt
     8701 gccctggcgg cgcttgtcga tctcgttgag gcggtggtcg agcgcgccga tcagcgcatc
     8761 gcggcgttcg cgcgaggtga ggaggtcgtc ttcgagatag gggttgcggc gcaccaccca
     8821 gatgtcgccg aggacctcgt acagcatccg cgccgagcgg ccggtgacgc gttcggtgcg
     8881 gagctggtcg agcaccgccc aggcctcggc cccgagcagg cggatgacga tctcgcggtc
     8941 ggaaaacgag gtgtagttgt acggaatctc gcgcaggcgt tggctcattg ggctacccgg
     9001 aagcggctgc agggaagcgt tccattctag cgaaccgcag tgcaccatgc agcaaaaatc
     9061 aagaccttaa gagcagcatg gattcgtgct ccgcggcctg gcgaggcgtg tgcctcagcg
     9121 tgcggcggtg agcgcgatct cgatccgcca gcccgggtcg gcgagcccgg cgacctggac
     9181 gcaggcgcgc accggggcgc tcccgggcgg aacccaggcg tcccacaccg tgttcatgcc
     9241 ggcgtagtcg gccatgtcca cgaggtagat ggtggccatc aggatgcgcg cgggatcgct
     9301 gccgagcctg gcgagctggc ggccgatgga ttccagcacc tcgcgcgtct gggtctcgat
     9361 cgggccggcg ctgctcgccg ggacctcgac cagatgaatg atgccggcgt ggatgacggc
     9421 gtcggcgtag cgggcagtga cgccgtggcg ttcgatggcg gacatgtggg gcgctccgtt
     9481 gcggggaaag gggccgtcga gtataggcga gggggcggcc tgggcgtctt ctccaccgcg
     9541 cgcgctcacg ccccggccga tggcagcgcc catgcgatcg ctgcgtagcg caggcccttg
     9601 ccgagcgcca tccacgccag gcacgcgaag gcgttcaggc gcagcgcgcc tgcggcggcg
     9661 cacagcgcat cgccgatcaa gggcacccag gacagcagca gggcgaggct gccccagcgc
     9721 tgcagggtgc gcgcgtgcgc gccgggctcc ttgcgtggca acaggcgacc gagcgcgtag
     9781 gtgctcatgc cgcccgcggt attggccacg gtggcgacga gcagggccgc gggcgtcagc
     9841 tcggggcgca gcgtcagcag ggcggcgaac accgcctccg agccgcccgg cagcagggtg
     9901 gcggcgagga aggcggaggc ggcgaggcct gcgagcggcg cgagctcccc gctcagcacg
     9961 accgcggcct cgcgcggagt cccgcccatg cggctccgtc gatgcgaagt gcattgacga
    10021 ggttgtatgt catatgcaaa atccggctac gcgttttgcg taaatcagga tgaggagaca
    10081 cgatcatgaa gcgaattctc ggcgccggct gcgctgtgct cgtacttgcg gcgctcgctc
    10141 ccgcgcaggc ctgggcaaac ccccagcacg aacgcatgaa gcgctgcaat gccgaagcga
    10201 aggagcaggc gctcaagggc gaggcacgca aggccttcat gggtacctgc ctgcgtggca
    10261 agcatgacgc cgcggcgccc gcggccgcgc ccggcgcacc ggtcgcggcc gcagccgcag
    10321 ccgctgtgcc cgcacaggcg ggcgccggcg cgcccgcaca ggccgcagcc ccggcgcccg
    10381 cagccgttgc gcccgcggtt gcagcgccag cggtcgcggc ggagtcggtg cagaaggtct
    10441 cgagcgagga caaggcgcga cagaaggcct gcaaccgtgc ggccaccgag cagtcgctgc
    10501 gcggggccaa gcgcaaggcc ttcatcggcg agtgcatgag cggctgatcc ggtcgtgtcc
    10561 atgggggcgc gctgcgcgcg cgggcgcctc cgcttcatgc gtcccgccgg tcgccgcgtc
    10621 ggtggggtca gacgatgtcg aagaacacca ggtcgcgctc gacctcggtc gtcgagaagc
    10681 cgcagcccag ccggccgggg ccgtcgagca gcatgctctc ctgacgcacg aagcactccg
    10741 gcttgccctc gatcgccacg aagctgccgt tggtgctctg gtcgaacagc acgaagccct
    10801 cggggcggcg ctcgatgcgg gcgtgctggc gcgatgcgcg cggatccatg atggtgatgt
    10861 cgttggccag ctcgcggcca agcagcagca ccgggcgcag ctcctcaacg aacacgacct
    10921 cctgctgatg acgcaggcgc agccggctcg acaggcgggt ggcgcccgga accgaggtga
    10981 ccagcccgct gcgctggccg atcgcgtgca ccggaatccc gatgcgcgtc cacaccggcc
    11041 cgctcagcgg ctgcgagccg accagctgcc gtgcggcgcc gccgagcagc atcaccgccg
    11101 tgccggagat caacgcctgc ccgctctcgg ccaggtgagc gagctggcgg gccaccgcgg
    11161 ggccatcgcc gacgggctcc tcggcgctgc cttcgagcgc gccgtaatgt acgccgatgc
    11221 gcaccgtctg cttgctgccg agcaggggag gcagggcatg gatgcgctcg agcgcctcgc
    11281 tcgccgcatg cacggcagcg tcgccgcgct cgaatgcggc gaccgtctgc tccgcatcgt
    11341 cgatcagtac ctggcctccc tgcatcacca ccgcacgctc gatccgccgc gcgtgacgct
    11401 cggccgcgtg gcgtgcctcg tccgcaccca ggcgctcggc gagcaccgca tccaccgggt
    11461 ggagggcgac cagcacgcaa aggttctttc gctcggacat cgcaggggtt tccgtgtcag
    11521 atctcgtggc cggcgcggcc ggcccggaac aggatcatgc ggacgtcgcg ccggatccgc
    11581 aaggcgccga cgccagcagc gggcccggcg gcgcatcgct caggcgcatt cacgctcttc
    11641 ctggtcgcct gcgcggaaca gcgtcacgct ggcgccgagc gtgcggtcgg ggagctcggg
    11701 cggatcgaag gcggtgtcgc cctcctcgac cacggtgttc tgcgtgaggc cgacgaagtc
    11761 gaacaggcgc tggtcggcaa ggtgcgaggg gacgacgttc ttcagcgcgg tggcgagcga
    11821 ttcgatgcga cccgggtagt cgcgcgccca gccctgcagc atgttcttga tcagcttgcg
    11881 ctgggcgttc tcctgcgagc cgcacaggtt gcaggggatg atggggaaat ccatcgtgcg
    11941 cgcgaagcgg gcgatgtcgg cctcggtgca gtaggcgagc ggacggatca ccacgtgctt
    12001 gccgtcgtcg ctgaccagct tgggcggcat ggccttgatc ttgccgccaa agaacatgtt
    12061 gaggaacagg gtctcgagca tgtcgtcgcg gtggtggccg agcgcgatgc gggtggcgcc
    12121 gagctccgcc gcggtgcggt agatgatgcc gcggcgcagg cgcgagcaca gcgagcaggt
    12181 ggtcttgccc tcggggatct tgtccttgac gatcgagtag gtgtcctcgg tgacgatgcg
    12241 gtactcgacg ccgatcgact cgaagtaggc cggcagcacg tggtcgggga agccgggctg
    12301 cttctggtcg aggttcatcg ccacaatgcg gaagtccacc ggcgcgcgct cgcgcagcgc
    12361 gagcaggcag gacagcaggg tgtaggagtc cttgccgccg gagacgcaca ccatc
//
LOCUS       DAOTIN010000091        12345 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_6109_length_12345_cov_9.845972, whole genome shotgun sequence.
ACCESSION   DAOTIN010000091 DAOTIN010000000
VERSION     DAOTIN010000091.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 12345)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 12345)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12345
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6109_length_12345_cov_9.845972"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            129..800
                     /locus_tag="P5537_12455"
     CDS             129..800
                     /locus_tag="P5537_12455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004356979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HRV78893.1"
                     /translation="MPTLSLHQLRTRHVGPIDLDIAAGECVCIRGASGSGKSLLLRAI
                     ADLDPHAGAAVLDGRACASMPGPAWRRQVALVMAEGQWWADSVGEHFPGGCTPASLDR
                     LGLPADALGWQVARCSTGERQRLALLRTLMQQPAVLLLDEPTGNLDEDSTARVESLLG
                     DYRREHAAALLWVSHDPRQAARVAQRRFMLEDGRLVEEGEEEDGGESTSVGHARCPDA
                     GDAAW"
     gene            794..1594
                     /gene="fetB"
                     /locus_tag="P5537_12460"
     CDS             794..1594
                     /gene="fetB"
                     /locus_tag="P5537_12460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron export ABC transporter permease subunit
                     FetB"
                     /protein_id="HRV78894.1"
                     /translation="MVIELSVLDLALAALLILALAGVSLRLGLGIGQRLVVSAARTTI
                     QLLLIGLVLKLLFDNAHFLWVAAMAAVMITAAGREVMARQKRRFVGWWGFGLGTLSMF
                     VSSFTVSVLALLVVISNTPWYAPQYAIPLLGMVLGNTMNGIALGLDRLTHEASARRAV
                     LEARLALGQDWDETIADTRREAIRVGMIPIINAMAAAGIVSLPGMMTGQILAGTPPVE
                     AVKYQILVMFLIAGGTGFGTVVAVSLGARRLFDERQRLRLDRLRTSAD"
     gene            1684..2982
                     /locus_tag="P5537_12465"
     CDS             1684..2982
                     /locus_tag="P5537_12465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004356975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide pyruvyl transferase family
                     protein"
                     /protein_id="HRV78895.1"
                     /translation="METTAAGALRAPLILFGAFDRHNLGDLLLGRIAAALAARLLPGR
                     EVRFAGLASRDLRADGGARVQALAELARDWHPVHREGAPAWPPASPPALLQVGGEILG
                     CGAWEAAVMLLDTTGAAHAIALHDRDPSAREAWARGVLGSARGLPYLAPHAALPPGTR
                     IVHTGIGGVGFASLPAARRAEALTELHTAARVQVRDRCTRDALAAAGLDAELVPDPAV
                     LVERLLGAEVTRSAATGEIAVLRARFPRGYVAVQLAAESGDDATLATLADELAATARD
                     RGLSIVLFCAGRAPWHDDPEVLERLRRRLPDPKSAVVAESRHVLDLCALIASAALCCA
                     SSLHARIVADAFARPAISIACGTAQAAKLRAWLDSWHSPRRHHLAAPGNLRTLAHSVL
                     SEAPSERGAHAARLADLAEAAARSAFAQLFDPLEPEDKTP"
     gene            2979..4055
                     /locus_tag="P5537_12470"
     CDS             2979..4055
                     /locus_tag="P5537_12470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004356973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkene reductase"
                     /protein_id="HRV78896.1"
                     /translation="MTDLFTPLQAGELALPNRILMAPLTRCRAEAGHVPGELMATHYA
                     QRASAGLLIAEATMAMEGNSAFWHEPGIHSEAQVAGWKKVTDAVHAAGGRIVLQVWHG
                     GRACHPLLNDGRQPVAPSALAITGDEVHTPKGKQPYVVPRELRDDELPAIVAGFARAA
                     ENARAAGFDGVEVHGANGYLLDEFLRDGSNQRSGPYGGPREHRARLLFEVIDAVCKVW
                     GSGRVGVRLSPLNSYNDMIDSDPIGLVEWLAGRLDDYRLAYLHLMRGDFFGKQHGDVV
                     TPVRAAYRGVLIGNMGYSADEASTAIAAGQLDAVAFGTAFLANPDLPERIRRKAALNA
                     PDPATFYTPGPRGYTDYPTLAQSA"
     gene            complement(4096..5154)
                     /locus_tag="P5537_12475"
     CDS             complement(4096..5154)
                     /locus_tag="P5537_12475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HRV78897.1"
                     /translation="MSAISALRLTAWRQVLPTLALATLAGWLAERLHLPLPWMIGPLF
                     AVAGARMADIDLRPLPGGRQTGQWAIGAALGLYFSPEVVAQLGLHAPLVIAAALGSLV
                     LGMAYAFILLRLGGVDAPTAFFAALPGGASEMANLADRHGGAVDRIAAAHAIRVMMVV
                     SVLPFALTFAGVQGSDVYVPLAREVDAQHFPLLVGASLLGVGAFKLLRIANAWVLGPL
                     LGVALATLAGVPLSALPPWVVNGGQLLIGCALGCRFSRAFFRAAPRFMSVAALTGAMS
                     IVLAFALAALLGLVSEVPLPTLALATAPGGVSEMCITAKVLQLGVPLVTVCHVLRVVV
                     LTVGAQWSFGLFRRLVAA"
     assembly_gap    5171..5270
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<5271..6352)
                     /locus_tag="P5537_12480"
     CDS             complement(<5271..6352)
                     /locus_tag="P5537_12480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004316094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HRV78898.1"
                     /translation="MRISGARAWVKTVLAFVALAAATVTARAEQIADRFDQARLEGVV
                     VVYAATDLEVVKPVIDDFEALHPGVRVQYHDMHSAQLHARVVDEARRGVPGADVVWSS
                     AMDLQVKLVNDGHAQPHRSAETAALPRWAVWKDEAFGTTYEPAVIVYNKRLLDGADVP
                     GSHAELIRLLDRDPAQLRGRIATYDPERSGLGLLLHTQDAQANPIVFWQLARGMGRQG
                     LEQHAVSSEMLDRVAAGKLVLAYNVLGSYAHRRARSDPALGVALPQDYTLVLSRVAFI
                     ARGARHPAAARLWLDHLLSTRGQALLAANLGLLPVRTDAGTAGADSAAALLHQNLKHA
                     FRPIRIGSGLLAYQDQAKKQAFLRQW"
     gene            6496..7185
                     /locus_tag="P5537_12485"
     CDS             6496..7185
                     /locus_tag="P5537_12485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV78899.1"
                     /translation="MRLLLVEDHAELAEWVARSLRHAGFVLDVLNRGDHADQALRTER
                     YDLVILDLSLPGLDGLEVLRRLRSRESGPDKPAPTPVMVLTARGSTDERVLGLNLGAD
                     DYLPKPFELAELEARIKALLRRAGNQVPLVRLGRLEFDTTTRMAAVDGQALALTPREL
                     AVLEALLARVGRPVAREALFEKVFEFDADARVEAIEIYVSRLRKKLEGAGVAINTLRG
                     LGYLLAEKPAA"
     gene            7187..8683
                     /locus_tag="P5537_12490"
     CDS             7187..8683
                     /locus_tag="P5537_12490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase N-terminal
                     domain-containing protein"
                     /protein_id="HRV78900.1"
                     /translation="MAGSSGSGPEGLGADERGRPTTGRTTPGTAAAHGGSLRRRVLVW
                     LLPPLAVLLLVNAFFTYRSALDAVNQAYDRTLTASVRAIGERTHSLAGQIQVDIPYAA
                     FEGFEADAAERIFHAVFDPAGGLVTGYVDLRPPELPADDGSVRIFDLRYAGETVRLAA
                     MRKRLYDPALRGGDAVLIVFAETTGARRALARDLFVASLQRQSLLVAVGAILVLAALG
                     TAFRPLLRVRDHMRTRDEEDLTPIRMERVPSEIAPLIDAINHHMERLSAMLAARRRFL
                     ADAAHQIRTPLAVLTTQAEYGLRQTDPEEMLETFASLLRSTRAARRLANQMLTLSRAE
                     AVNGVIGERATLDLAGLVKDVAMELAPLALKRDIDLAYEGIGHALAIQGNAPMLREMV
                     SNLIDNAIRYSSPDSAVTVAVATFGEDAVVSVCDQGPGIPAAERERVFQRFYRILGQG
                     DSEGSGLGLAIVREIALAHGGRVTLRDGEGGRGLCVEVELPLGSTPGA"
     gene            8806..9849
                     /locus_tag="P5537_12495"
     CDS             8806..9849
                     /locus_tag="P5537_12495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004316087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porin"
                     /protein_id="HRV78901.1"
                     /translation="MQRLSAPALMAAALALPSLALAQSNVTVYGLIDLNLGYERSGSQ
                     RYEGVGHGELNGSRLGFRGTEDLGNGNKALFVLESGFDPSTGLAEQGGRLFGRQSFVG
                     LENGLGRVTLGRQYSPAFDALDPFDATGNADRSAGLLIRKTGAVKPAYEVRFDNMIKY
                     RSAKLSGFELEAGYWFGKEAGTDSTARQEGDGHGIALLYANGAFAGALTTQSVQRDAT
                     GGKVRTSGFGAAYDFGTFKPYFAWSQDKESGSVGSGKARSWDLGTEIRIDPANTVALS
                     YADRDESDGAASEDAHGWSAYYLHALSKRTTVYAGYSQLDNDNGANYAIGNLSPAAGD
                     KHQVMMAGMRHRF"
     assembly_gap    10357..10456
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(10795..12297)
                     /locus_tag="P5537_12500"
     CDS             complement(10795..12297)
                     /locus_tag="P5537_12500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter permease"
                     /protein_id="HRV78902.1"
                     /translation="METLSMLMQGFAVAGTPENLMIALIGCFIGTVVGLLPGLGPING
                     VAILLPIAFAMKLPPESALILLCAVYAGCEYGGRISAILINVPGDAGAVMTTLDGYPL
                     AKKGLAGPALSMSALASFTGALLATIGIVAFAPLLAEWAIAFGPAEYFALMVLALSCL
                     GGLVGDSLPKAMTACLIGLLLSTVGIDANSGVYRYTFDMLHLQDGIPFIVIVIGLFAV
                     SELMLMLQNEHTASEPITITGRILFNMKELMLAKWTMLRSAFSGFFIGVLPGAGATIA
                     SAMCYAMERRMAGKDHQFGNGDIRGVAAPEAANNASANGSLVPMLTLGVPGSGTTAVM
                     IGALTLYNITPGPTLFQDQPVIVWGLIASLFIANVMLLVLNIPLIRVFVKFLSIPNWL
                     LVPGVAAISLVGVYAVHGTTFDLILGTLIGGVGYLLRVMNFPIAPFILGFVLGDMMEQ
                     NLRRALSISDGDVGVLFASPISIGLWVAAVAMLVGPRLMRMIEQRKAAAA"
BASE COUNT         1843 a         4477 c         4237 g         1588 t
ORIGIN      
        1 tttgccagcg ccgcattcgc gcctgccggc gctcctacag gacaccgccg cggcttcggg
       61 gggcgagcgc gtgatcccac cggcggcgcc gcattgaaaa cctcgcccgg acacgcgaac
      121 atcccgccat gcccaccctc tccctgcacc agctccgcac ccgccacgtc ggcccgatcg
      181 acctcgacat cgccgccggc gaatgcgtct gcatccgcgg tgcctcgggc agcggcaagt
      241 ccttgctgct gcgcgcgatc gccgacctcg acccgcacgc cggcgcggcc gtgctggacg
      301 ggcgcgcgtg cgcatccatg ccgggcccgg cctggcggcg ccaagtggcg ctggtgatgg
      361 ccgagggcca gtggtgggcc gacagcgtgg gcgagcactt ccccggcggc tgcacgcccg
      421 cctcgctgga ccgcctgggc ctgcccgccg acgcgctcgg ctggcaggtg gcgcgctgct
      481 ccaccggcga gcgccagcgc ctcgccctgc tgcgcacgct gatgcagcag cctgcggtgc
      541 tgctgctcga cgaacccacc ggcaacctcg acgaggacag caccgcccgc gtcgagtccc
      601 tgctcggcga ctaccggcgc gagcacgccg ccgcgctgct gtgggtcagc cacgacccgc
      661 gccaggccgc gcgggtggcg cagcgccgct tcatgctcga ggacggtcgg ctggtcgagg
      721 aaggcgaaga ggaagacgga ggcgagtcca cgagcgtcgg ccacgcccgg tgccctgacg
      781 cgggggacgc ggcatggtga tcgagctctc ggtgctcgac ctcgcgctcg ccgcgctgct
      841 catcctcgcg ctcgccggcg tgtcgctgcg cctcgggctg gggatcgggc agcgcctggt
      901 ggtgtcggcg gcgcgcacga cgatccagct gctgctgatc ggcctggtgc tcaagctgct
      961 gttcgacaac gcgcacttcc tgtgggtcgc ggcgatggcc gcagtgatga tcaccgccgc
     1021 cgggcgcgag gtgatggcac ggcagaagcg ccgcttcgtc gggtggtggg gcttcgggct
     1081 gggcacgctg tcgatgttcg tatcctcctt caccgtgagc gtgctggcgc tgctcgtggt
     1141 gatcagcaac acgccctggt acgcgccgca gtacgcgatc ccgctgctcg gcatggtgct
     1201 gggcaacacc atgaacggca tcgccctcgg gctggaccgc ctgacccacg aggcgagcgc
     1261 gcgacgcgcg gtgctcgagg cccggctcgc gctcggccag gactgggacg agaccatcgc
     1321 cgacacccgg cgcgaggcga tccgcgtcgg catgatcccg atcatcaacg ccatggcggc
     1381 agccggcatc gtcagcctgc ccggcatgat gaccggccag atcctcgccg gcacgccgcc
     1441 ggtggaggcg gtgaagtacc agatcctggt gatgttcctg atcgccggcg gcaccggctt
     1501 cggcaccgtg gtggcggtga gcctgggcgc acgccggctg ttcgacgagc gccagcgcct
     1561 gcgcctcgac cgcctgcgca ccagcgcgga ttgacgggga cgcgcaggat gaacccggct
     1621 gaccccgcgt tgacgggcgc agacgtggcc ggcacgcacg ccgcgccgac cggtgtcgcc
     1681 gccatggaaa ccaccgccgc cggcgccctg cgcgccccgc tcatcctgtt cggcgccttc
     1741 gaccggcaca acctcggcga cctgctgctc gggcgcatcg ctgccgcgct ggccgcacgc
     1801 ctcctgcccg ggcgggaagt gcgcttcgcg ggcctcgcca gtcgcgacct gcgggcggac
     1861 ggcggtgccc gcgttcaggc gctcgccgaa ctcgcccggg actggcatcc ggtccaccgc
     1921 gagggggctc ccgcatggcc gcccgcatcg ccccccgcgc tgctccaggt cggcggcgag
     1981 atcctcggct gcggcgcctg ggaggcggcg gtgatgctgc tcgacaccac cggcgccgca
     2041 cacgcgatcg cgctgcacga ccgcgacccg agcgcgcgcg aggcctgggc gcgcggcgtg
     2101 ctcggcagcg cgcgcgggct gccctacctc gccccccatg ccgcgctgcc gcccggcacc
     2161 cgcatcgtgc acaccggcat cggtggcgtc ggcttcgcga gcctgcccgc ggcgcggcgc
     2221 gccgaggcgc tcaccgagct gcacacggcc gcgagggtgc aggtgcgcga ccgctgcacg
     2281 cgcgacgcgc tcgccgcagc gggcctcgac gcggaactcg tacccgaccc ggcggtgctg
     2341 gtcgaacgcc tgctcggcgc cgaggtgaca cgcagcgccg cgacgggcga gatcgcggtg
     2401 ctgcgtgcgc gcttcccgcg aggctacgtc gcggtgcagc tcgcggccga gtccggcgac
     2461 gatgccaccc tggccacgct cgcggatgag ctcgccgcaa ccgcgcgcga ccgcggcctg
     2521 agcatcgtgc tgttctgcgc cggacgcgca ccctggcatg acgacccgga agtgctggag
     2581 cggctgcggc gccgcctgcc cgacccgaaa tccgcggtgg tggccgagtc gcgccacgtc
     2641 ctcgacctgt gcgcgctgat cgcgagcgcg gcgctgtgct gcgcgagcag cctgcacgcg
     2701 cgcatcgtcg ccgacgcctt cgcccgcccc gcgatcagca ttgcctgtgg cacagcgcag
     2761 gccgccaagc tgcgcgcctg gctcgacagc tggcactcgc cgcgacgcca tcacctggcc
     2821 gcgccgggga acctccgcac gctcgcgcac tccgtgctga gcgaagcgcc aagcgaacgc
     2881 ggggcccacg ccgcacgcct cgccgacctc gccgaggcgg cggcccgcag cgcattcgcg
     2941 caacttttcg atccgctcga acccgaggac aagaccccat gaccgatctg ttcacccccc
     3001 tgcaggccgg cgagctcgcc ctgcccaacc gcatcctgat ggccccgctc acgcgctgcc
     3061 gcgccgaagc cggccacgtg cccggcgagc tgatggccac ccactacgcc cagcgcgcca
     3121 gcgccggcct gctgatcgcc gaggcgacga tggcgatgga gggcaactcc gccttctggc
     3181 acgagcccgg catccactcc gaggcccagg tcgccggctg gaagaaggtc accgacgcgg
     3241 tgcatgccgc cggcgggcgc atcgtgctgc aggtctggca cggcggccgc gcctgccatc
     3301 cgctgctcaa cgacggtcgc cagccggtgg cgccgagcgc gctcgcgatc accggcgacg
     3361 aggtgcacac gcccaagggc aagcagccct acgtggtgcc gcgcgagctg cgcgacgacg
     3421 agctgccggc catcgtcgcc ggcttcgcac gcgcggccga gaacgcgcgc gcggccggct
     3481 tcgacggcgt ggaggtgcac ggcgccaacg gctacctgct cgacgagttc ctgcgcgacg
     3541 gcagcaacca gcgcagcggc ccctacggcg gcccgcgcga gcaccgcgcg cgcttgctgt
     3601 tcgaggtgat cgacgcggtg tgcaaggtgt ggggcagcgg ccgcgtcggc gtgcgcctgt
     3661 cgccgctcaa cagctacaac gacatgatcg acagcgaccc gatcggcctc gtcgaatggc
     3721 tcgccggccg cctcgacgac taccgcctcg cctacctgca cctgatgcgc ggcgacttct
     3781 tcggcaagca gcacggggac gtggtgacgc cggtgcgcgc cgcctaccgc ggcgtgctga
     3841 tcggcaacat gggctactcc gcagacgagg ccagcaccgc gatcgctgcc ggccagctcg
     3901 acgcggtcgc cttcggcacc gccttcctcg ccaaccccga cctgcccgag cgcatccgcc
     3961 gcaaggccgc gctcaacgca cccgatccgg cgaccttcta cactccgggg ccgaggggct
     4021 acaccgacta cccgacgctg gcgcaaagcg cctagaggcg cgccgatggt gtcggcacgc
     4081 acgggccgac accgctcacg ccgccaccag gcggcggaag aggccgaagc tccactgcgc
     4141 gcccacggtc agcaccacca cgcgcagcac gtggcacacg gtaaccaggg gcacgcccag
     4201 ctgcagcacc ttggcggtaa tgcacatctc cgacacgccg ccgggtgccg tcgccagcgc
     4261 cagggtcggc agcggcacct ccgagaccag tccgagcagg gccgcgaggg cgaacgcgag
     4321 cacgatcgac atcgctccgg tgagggccgc tacgctcatg aagcgcggcg cggcgcggaa
     4381 gaacgcgcgc gagaagcggc agccgagggc gcagccgatc agcagctgtc cgccattgac
     4441 gacccagggc ggcagcgccg agagcggcac gccggccagc gtcgccagcg ccacgccgag
     4501 cagcggcccg agcacccacg cgttggcgat gcgcagcagc ttgaacgccc ccacgccgag
     4561 caggctcgca cccaccagca gcggaaagtg ctgcgcatcc acctcgcggg ccaggggcac
     4621 atagacgtcg ctgccctgca ccccggcgaa ggtgagcgcg aagggcagca ccgacaccac
     4681 catcatgacc cggatggcgt gcgccgcggc gatgcggtcc accgcgccgc cgtggcggtc
     4741 ggcgaggttg gccatctccg aggcgccgcc cggcagggcg gcgaagaagg cggtcggcgc
     4801 atccaccccc ccgaggcgca gcaggatgaa ggcgtaggcc atgccgagca ccagcgagcc
     4861 cagcgcggcc gcgatcacca gcggcgcatg caggccgagc tgcgccacca cctccgggct
     4921 gaaatacagc ccgagcgccg ccccgatcgc ccattgcccc gtctgcctcc ccccggggag
     4981 cggacgcagg tcgatgtcgg ccatgcgtgc gccggccacg gcgaaaagcg gaccgatcat
     5041 ccacggcagc ggcaggtgca ggcgctcggc cagccagccg gcgagcgtgg cgagcgcgag
     5101 ggtgggaagg acctggcgcc aggcggtgag acggagtgcg gagattgcgg acatcgacgg
     5161 gagatcggga nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn tcccactggc
     5281 gcaggaaggc ctgcttcttg gcctggtcct ggtaggcgag cagcccggag ccgatacgga
     5341 tcggacggaa ggcatgcttg aggttctggt ggagcagggc ggcggcgctg tccgcgcccg
     5401 cggtgccagc gtcggtgcgc accggcagca ggccgaggtt ggcggcgagc agggcctggc
     5461 cgcgggtcga cagcaggtgg tcgagccaca gccgcgccgc cgccggatga cgggcaccgc
     5521 gggcgatgaa tgcgacccgg ctcagcacca gggtgtagtc ctgtggcagc gcaacaccga
     5581 gcgccgggtc gctgcgcgca cgccggtgcg cgtacgagcc gagcacgttg taggcgagca
     5641 ccagctttcc ggcggcgacg cggtcgagca tctcgctgct caccgcatgc tgctccaggc
     5701 cttgccggcc catgccgcgc gcgagctgcc agaacacgat cgggttggcc tgcgcgtcct
     5761 gggtgtgcaa cagcaggccg aggccggagc gctcggggtc gtaggtggcg atgcgcccgc
     5821 gcagctgcgc cgggtcgcga tcgagcaggc ggatcagctc ggcatggctg ccggggacgt
     5881 cggccccgtc gagcaggcgc ttgttgtaga cgatcaccgc cggctcgtag gtggtgccga
     5941 aggcctcgtc cttccacacc gcccagcgcg gcagcgccgc agtctcggcg gagcggtgcg
     6001 gctgggcgtg gccgtcattg accagcttga cctgcaggtc catcgccgag ctccacacca
     6061 cgtcggcgcc gggcactccg cgccgggcct cgtcgaccac gcgcgcatgg agctgtgccg
     6121 agtgcatgtc gtggtactgc acccggacac cgggatgcag ggcctcgaaa tcgtcgatga
     6181 ccggcttcac cacctcgagg tcggtcgccg catagacgac caccacgccc tccaggcgtg
     6241 cctgatcgaa acggtcggcg atctgctcgg cccgtgccgt cacggtcgcc gcggccagcg
     6301 cgacgaatgc cagcaccgtc ttcacccagg cccgcgcacc gctgatcctc atcccccttc
     6361 ctccttgtgc tccggatgca cgcgggtccg cattgcgatg cgggcaatgc cccgcatgcg
     6421 ccgccttgga cgcaccccgc ctttgcgccg ataatcccgc acacgccttt cgattcactt
     6481 tcagcgggaa caccgatgcg cctgttgctg gtcgaggacc acgccgaact cgccgaatgg
     6541 gtggcgcgct cgctccggca cgccggtttc gtgctggatg tgctcaatcg tggcgaccac
     6601 gccgaccagg ccttgcgcac cgaacgctac gacctggtga tcctcgacct gtcgctgccc
     6661 gggctggacg gcctcgaggt gctgcgccgc ctgcgcagcc gcgagagcgg ccccgacaag
     6721 ccggcaccca cgcccgtcat ggtgctcacc gcgcgcggca gcaccgatga gcgcgtgctc
     6781 gggctcaacc tcggcgccga tgattatctg cccaaaccct tcgagctcgc cgaactcgag
     6841 gcgcgcatca aggcgctgct gcgccgtgcc ggcaaccagg tgccgctggt gcgcctggga
     6901 cggctcgagt tcgacaccac cacccgcatg gcggcggtcg acggccaggc gctggcgctg
     6961 accccgcgcg agctggccgt tctggaagcg ctgctggccc gggtcggccg ccccgtggcg
     7021 cgcgaggccc tgttcgagaa ggtgttcgag ttcgatgcgg acgcgcgcgt ggaggcgatc
     7081 gagatctacg tctcgcggct gcgcaagaag ctcgaaggcg caggcgtggc gatcaacacg
     7141 ctgcgcggcc tcggctacct gctcgccgag aagccggcag cctgacatgg ccggcagttc
     7201 cgggtccgga ccggaaggcc tcggcgcgga cgagcgcggg cggcccacga ccggacgcac
     7261 gacgccgggg accgccgccg cacacggcgg cagcctgcgc cgacgcgtgc tggtgtggct
     7321 gctgcctccg ctcgcagtgc tgctcctcgt caatgccttc ttcacctacc gcagcgcgct
     7381 cgacgcagtg aaccaagcct acgatcgcac gctcaccgca tcggtgcgcg cgatcggcga
     7441 acgcacccac tcgctcgccg gccagatcca ggtcgacatc ccctacgccg ccttcgaagg
     7501 cttcgaggcc gacgccgccg agcgcatctt ccatgccgtg ttcgaccccg cgggcgggct
     7561 ggtcaccggc tacgtcgacc tgcgcccccc ggagctgccc gcggacgacg gcagcgtgcg
     7621 catcttcgac ctgcgctatg ccggcgagac ggtgcgcctg gcggcgatgc gcaagcgcct
     7681 ctacgacccc gcgctgcgcg gcggcgatgc ggtgctgatc gtcttcgccg agaccaccgg
     7741 cgcgcgccgg gcgctggcgc gcgatctgtt cgtcgccagc ctgcagcgcc agtcgctgct
     7801 ggtggcggtg ggggcgatcc tggtgctggc cgcgctcggc accgcattcc gcccgctgct
     7861 gcgcgtgcgc gaccacatgc gcacacgcga cgaggaggat ctcaccccga tacgcatgga
     7921 acgcgtgccg agcgagatcg caccgctgat cgacgcgatc aaccaccaca tggagcgcct
     7981 gtcggcgatg ctcgcggcgc gccggcgctt cctcgccgac gccgcgcacc agatccgcac
     8041 gcccctcgcg gtgctcacca cgcaggctga atacggcctg cgccagaccg acccggagga
     8101 gatgctggag accttcgcca gcctgctgcg cagcacccgg gcggcgcgcc ggctggccaa
     8161 ccagatgctg acgctgtcgc gcgccgaggc ggtcaacggc gtgatcggcg agcgcgccac
     8221 gctcgacctc gccggcctgg tcaaggacgt cgcgatggag ctcgccccgc tcgcgctcaa
     8281 gcgcgacatc gacctcgcct acgagggcat cggccacgcc ctggccattc agggcaacgc
     8341 cccgatgctg cgcgagatgg tctccaacct gatcgacaac gccatccgct acagctcgcc
     8401 cgactcggcg gtgaccgtcg ccgtcgccac cttcggcgag gacgcggtgg tgagcgtctg
     8461 cgaccaggga ccgggcattc cggcagccga gcgcgagcgc gtgttccagc gcttctaccg
     8521 catcctcggc cagggcgaca gcgaaggcag cggcctgggc ctggcgatcg tgcgcgagat
     8581 cgcgctcgcc cacggcggcc gcgtgacgct gcgcgacggc gagggcgggc gcggcctatg
     8641 cgtggaggtc gagctgccgc tgggcagcac ccccggcgcg tgaaccggcc tcttctcctc
     8701 gtctccgcat cacgctgaaa gccgatcgaa aggcgtcggc gctgcaatgc gcgccacgcg
     8761 cccgattcac ccggcgcgta catccgaacg atcgaggaga ctcccatgca acgcctttcc
     8821 gcgccggccc tgatggccgc cgccctcgcc ctgccatcgc tcgcgctggc ccagtccaac
     8881 gtcaccgtgt acggcctgat cgacctcaac ctcggctacg agaggtccgg atcgcaacgc
     8941 tacgagggcg tcggccacgg cgagctcaac ggctcgcgcc tcggcttccg cggcaccgaa
     9001 gacctcggca acggcaacaa ggccctgttc gtgctcgaga gcggtttcga cccctcgacc
     9061 ggcctcgccg agcagggcgg gcggctgttc ggccgccagt ccttcgtcgg cctggagaac
     9121 ggcctcggcc gcgtcaccct agggcggcag tactcgcccg ccttcgatgc gctcgacccc
     9181 ttcgacgcca ccggcaacgc cgaccgcagc gccggcctgc tgatccgcaa gacgggcgcc
     9241 gtcaagcccg cctacgaggt gcgcttcgac aacatgatca agtaccgctc ggccaagctc
     9301 tcgggcttcg agctcgaggc cggctactgg ttcggcaagg aggccgggac cgattcgacc
     9361 gcgcgccagg aaggcgacgg ccacggcatc gcgctgctct acgccaacgg tgcgttcgcc
     9421 ggcgcgctga cgacccagtc cgtacaacgc gacgccaccg gcggcaaggt gcgcacgagc
     9481 ggcttcggcg cggcctacga cttcggcacc ttcaagccct acttcgcctg gtcgcaggac
     9541 aaggagagcg gcagcgtggg cagtggcaag gcgcgcagct gggacctcgg caccgagatc
     9601 cgcatcgatc ctgcgaacac cgtggcgctg agctacgccg accgcgacga atccgacggc
     9661 gccgcgagcg aggatgccca cggctggtcg gcctactacc tgcatgcgct gtccaagcgc
     9721 accacggtgt acgccggcta ctcgcagctc gacaacgaca acggcgccaa ctacgccatc
     9781 ggcaacctga gtccggcagc cggggacaag caccaggtca tgatggccgg catgcgccac
     9841 cgcttctgat cgatccggca aggcgacgct ttgttgcaag gcaggtgcac gcgggaacct
     9901 cccgctccac ctgccttttt gcgtctacgc gccacctttg cagcgacggt gcccggcaac
     9961 cccgaccaca gccgaacccg gcggcggccg tctcgctttt ctgccgtttc cttcccttcc
    10021 cgaacccgcg accccgacat gaagcaaggc ccgctccagg gcgcctcggc ctgcggcacg
    10081 gcgggcgagg tcacgccgga aggttcgcgg ctgccgccgc tcctacaggc gggccgggac
    10141 gcgtggcggg gctccgggac acgtggtggt tcctgtagga gcgccggcag gcgcgaaaac
    10201 ggcggtgtcg tccgggacgc gcgtcatttg ccgcaccgcc ggattcgcag ctgccgcagc
    10261 gcctacaggc gggccgggac gcgtggcggg gctccgggac gcgtggtggt tcctgtagga
    10321 gcgccggcag gcgcgaaaac ggcggtgtcg tccgggnnnn nnnnnnnnnn nnnnnnnnnn
    10381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10441 nnnnnnnnnn nnnnnncgtg gtggttcctg taggagcgcc ggcaggcgcg aaaacggcgg
    10501 tgtcgtccgg gacgcgcgtc atttgccgca ccgccggatt cgcagctgcc gcagcgccta
    10561 caggcgggcc gggacgcgtg gcggggctcc gggacgcgcg ctggttcctg taggagcgcc
    10621 ggcaggcgcg aatggggcgc tggcgatacg ctcggcgctc aggcgcaccc gcaaaaaaat
    10681 gagcgcccgc aggcgctcat cgaaaatgca gcaggcccga acggaggccc gccgcgatcg
    10741 cggattccgg tcatgggagg agcaccccgg aatccgtgga ggtgatcgtc gcgatcaggc
    10801 ggcggccgcc ttgcgctgct cgatcatgcg catcaggcgc ggccccacca gcatcgccac
    10861 cgcagccacc cacaggccga tcgagatcgg gctggcgaac agcacgccga catcaccgtc
    10921 gctgatcgac agagcgcggc gcaggttctg ctccatcatg tcgccgagca cgaagccgag
    10981 gatgaagggc gcgatcggga agttcatcac ccgcagcagg tagccgacgc cgccgatcag
    11041 ggtgccgagg atgaggtcga aggtcgtgcc atgcaccgca tacacgccca ccagcgagat
    11101 cgccgccacg cccggcacca gcagccagtt ggggatcgag aggaacttca cgaacacgcg
    11161 gatcagcggg atgttgagca ccagcagcat cacgttggcg atgaagagcg aggcgatcag
    11221 gccccacacg atcaccggct ggtcctggaa cagcgtcgga ccgggggtga tgttgtacag
    11281 cgtgagcgca ccgatcatca ccgcggtggt gcccgagccc ggcacgccca gggtcagcat
    11341 cggcaccagc gagccgttgg ccgaggcgtt gttggccgcc tcgggtgccg cgacgccgcg
    11401 gatgtcgccg ttgccgaact ggtggtcctt gcccgccatg cggcgctcca tcgcgtagca
    11461 catcgccgag gcgatggtgg cgccggcgcc cggcagcacg ccgatgaaga agccggagaa
    11521 ggcggaacgc agcatggtcc acttggccag catgagctcc ttcatgttga acaggatgcg
    11581 gccggtgatg gtgatcggct cgctcgcggt gtgctcgttc tgcagcatca gcatcagctc
    11641 gctgaccgcg aacaggccga tcacgatgac gatgaaggga atgccgtcct gcaggtgcag
    11701 catgtcgaag gtgtagcgat agacgccgct gttggcgtcg atacccacgg tcgacagcag
    11761 caggccgatc aggcaggcgg tcatcgcctt gggcagcgag tcgccgacca ggccgccgag
    11821 gcaggacagc gccagcacca tcagcgcgaa gtattccgcc gggccgaagg cgatcgccca
    11881 ttcggcgagc agcggcgcaa aggcgacgat gccgatggtg gcgagcaggg cgccggtgaa
    11941 ggaggcgagc gccgacatcg acaacgccgg cccggcgagg cccttcttgg cgagcggata
    12001 gccgtcgagc gtggtcatca ccgcaccggc gtcgccgggc acgttgatca ggatcgcgga
    12061 gatgcggccg ccatactcgc agccggcata caccgcgcac agcaggatca gcgccgactc
    12121 gggcggcagc ttcatcgcga acgcgatcgg cagcaggatg gcgacgccgt tgatcgggcc
    12181 gaggccgggc agcaggccga ccacggtgcc gatgaagcag ccgatcagcg cgatcatcag
    12241 gttctcgggc gtgccggcga cggcgaagcc ctgcatgagc atagacaagg tttccatggc
    12301 ttaccccagg atgccgttga gccacagccc ggtcggcagc gcgac
//
LOCUS       DAOTIN010000092        12269 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_6171_length_12269_cov_9.252661, whole genome shotgun sequence.
ACCESSION   DAOTIN010000092 DAOTIN010000000
VERSION     DAOTIN010000092.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 12269)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 12269)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12269
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6171_length_12269_cov_9.252661"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1175
                     /locus_tag="P5537_12505"
     CDS             <1..1175
                     /locus_tag="P5537_12505"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78903.1"
                     /translation="RSDGNLDAYPLRAEMNPTRVKLTEGDLIRIYLAYLTDLAVSQVQ
                     TWSAEDTKGPLCRYVRRRFAHPCWPSSAQKSWADRLMRHWMAEAQILADTFHDRWQGG
                     LDVAEVKAAVDLVRALERRPEYLIADGVPEPVAVAAGALVDGEDKRLPFMVIDVGAGT
                     TDFGLFLLREDEQREITRVFQVPGSIKALMQAGDRIDMMLKKFILDAQGVDLTEPHGR
                     LVAADLSRRIRGLKERLFADTRVQYVLSDGTLGKIELGDFMASRPVREFSERVEQGFR
                     DVLEGLHDTWLSYLTKTDLTVILTGGGASLPMMRALAEGWVEVRGKRIARKLVNPLPS
                     WILGESPELEPVYPQLAVAIGGAAHELPETVDGPEAFAGGGGRTAYAVGNLQVSGA"
     gene            1196..4081
                     /locus_tag="P5537_12510"
     CDS             1196..4081
                     /locus_tag="P5537_12510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF499 domain-containing protein"
                     /protein_id="HRV78904.1"
                     /translation="MAVSKLPTRRAAAASWEMMGMSLKPWREIAVPHEDVLKGTFQQA
                     EFAADLSRVHLGTATAEYQDPSLFFQRTFITEGMRLLLDSVVHRLTGRGGDPVIQLQT
                     AFGGGKTHTMLAVYHLAKGEVSASDMPGIPSILNAAGVVEMPRARIAVLDGIRLSPNQ
                     PMKRDGLAVNTLWGELAWQLGGAEGYAMVREADESGTSPGKGVLADLLGRYAPCVILI
                     DELVAYIRQFEEGKTLSGGSFDSNLSFLQALTEALKAVPTAVLLASLPESDKEAGSQR
                     GVKALAALSHYFGRVQALWKPVSSEEAFEIVRRRLFSSIGDKLGAETVCRAFADYYIA
                     NAADLPHETQEARYFERLMHAYPIHPEVFVRLYEDWSSLDNFQRTRGVLKLMAKIIHR
                     LWKDNNSDLLIMPGSLPLYDADTRNESIYYLPQGWDPVLESDVDGERAETTELESVDT
                     RLGSVQACRRTARTIFLGSAPTTSSQMVRGIELERVLLGCVQPGQQIGVFKDALRRLN
                     DRLHYLNSGNNRFWFDTRPNLRREMEDRKRRFHDKDDVIPAVRDRVQRTLAPGVFGGV
                     HVFTASADIPDDWALRLIVLPPTAGYSRSGDQSAIRYATEILKHRGEQPRFKQNRLIF
                     LAPDADSVSRLKDQVRSVLAWQSIVADIKDLKLNLDQYQARQASRSLDDANEALRGMV
                     KESYRWMLAPAQFAERGKGLSELQWEAFQINSGAQNLTQEIERVLRENELLITEWAPI
                     HLHNVLKTWFWKDGTGEANALNVWQQTCHQLYLPRLKDDAVFHHTLAAGAESRDFFGF
                     AQGKEDGRYLGFSFAKRTTPILDTALILIEPSLAHAEAERIAAERAQEAAGAAAVTYP
                     LGTPPSAQQAADSGATTRVVATPVAATTAPRTHFFGTIDLDPVMAKRQFADIIDEVVL
                     NFTAKPGVKVRISIEIDAESEAGFEDGLQRAVRENCNVLRFKNAEFD"
     gene            4214..5317
                     /locus_tag="P5537_12515"
     CDS             4214..5317
                     /locus_tag="P5537_12515"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78905.1"
                     /translation="MLSELGLSVARSIPVEQVIGLATGNLSLHGGVIRDAAGRIVSHL
                     AMPASAGLLGAVPGLGAIGSVVTGIQMQALSANVAAVKAATDQILNYSIATTALSGLG
                     IVTSVTGFAYLASRLNRIDKRLSTLEKQTKAIKQFLQSSQHAQLMTAVDHLRLSQQAT
                     DGETRRHLLLQSKQLFTTLAHHYKVQLGEIDDITELNATEDCYVLACLGSVMAMSDLG
                     MGEAARDEMLRHYADWRVIARKHCGKLLLKDDPARLFDARYVQSVPAANLIRFLDFTN
                     DSNRGVQWFDELRRTLDKATLVRSAMSVVEPACIEYANKLLVKNEVLQGFNAHMGFLA
                     EKKLSLSYFAQRVEEIREREGAKFLVLQNTAPA"
     gene            complement(5526..8021)
                     /gene="gyrB"
                     /locus_tag="P5537_12520"
     CDS             complement(5526..8021)
                     /gene="gyrB"
                     /locus_tag="P5537_12520"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011237438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009330 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) complex [Evidence
                     IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HRV78906.1"
                     /translation="MSEPQNTPAPQAGNDYDESSIQQLEGLEAVRKRPGMYIGDTSDG
                     TGLHHMVFEVVDNSIDEALAGHCDDIVITIHADNSISVTDNGRGIPVGVKMDDKHEPK
                     RSAAEIVMCVLHAGGKFNQNSYKVSGGLHGVGVSCVNALSKWMNVTVARDGKRHLLEF
                     ERGKPQNRVIELVDGVEVSPARVIGETTKRGTKVHYLADEEIFGTVEYHYDILAKRLR
                     ELSFLNNGVKIRLIDQRTGKEEDFAFAGGVKGFVEYINRAKTVLHPNVFYATGTTRIP
                     TGHGHDAELAVEVAMQWNDSYQEQVLCYTNNIPQADGGTHLTGLRAAMTRVINKYIEE
                     NEIAKKAKVDITGDDMREGLACVLSVKMPDPKFASQTKMKLVSSEARPAVEEVVASKL
                     GDFLLENPIDAKTICNKIVEAARARDAARKAREMTRRKGVLDGVGLPGKLADCQEKDP
                     ALCELYLVEGDSAGGSAKQGRDRKFQAILPLKGKILNVEKARFDKLLQSQEIATLITA
                     LGTSIGKDDYKPEKLRYHRIILMTDADVDGAHIRTLLLTFFYRQMPELVERGHIYIAQ
                     PPLYKIKHGKTEIYIKDDTELNGHLLKLALDGAMLVPREGASPIADEALGGLARSYLL
                     AEAVIKRLASYIDPEVLQVMLAHDLEVSLEDEAAARASAERIQPHLPEGLQIYAEYHD
                     ESEGWRLTIERLHHGNRKFGWVEQDFLVSGDYRSIRNAAEAISGLIGPGAEIRRGEKR
                     QSVTRFADAIGWLLGEVERGLSKQRYKGLGEMNPEQLWETTMDPAVRRLLRVQIDDAI
                     AADEIFTTLMGDNVEPRRAFIEGNALYAQNIDV"
     gene            complement(8179..9300)
                     /gene="dnaN"
                     /locus_tag="P5537_12525"
     CDS             complement(8179..9300)
                     /gene="dnaN"
                     /locus_tag="P5537_12525"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004315516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HRV78907.1"
                     /translation="MLLLTTTRDALLAPLQSVAGIVEKRHTLPILSNVLIEKHADQLT
                     MLATDIEIQIRTTTGGHIGGEDASITVGARKLQDILRALPDSAEISLTLDDKRLTVKA
                     GRSRFQLQTLPAADYPRLNPPEDAGARLTIGQRAFKRQLAQVAYAMAQQDIRYYLNGL
                     LLIAEGSELRMVATDGHRLAYAASDLDAPLDAQHAQRTEAILPRKTVLELARQLADSD
                     DPLEILLAGNQAVFRFGPIELVTKLIDGKFPDYERVIPTAHPKLVSFARQPLLAALQR
                     AAILTNEKFRGVRMVLEDGVLRIVSTNAEQEEAMDELEIDYQGDKLDIGFNVTYLLDV
                     LNNLSSETVDWRFNDGNSSALITLPGNEKFKYVVMPMRI"
     gene            complement(9361..10878)
                     /gene="dnaA"
                     /locus_tag="P5537_12530"
     CDS             complement(9361..10878)
                     /gene="dnaA"
                     /locus_tag="P5537_12530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011763738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HRV78908.1"
                     /translation="MTQDFWSFCLSRLEQELPQQQFNTWIKTLRAEPGEGGWALVAPN
                     RFVLQWVRERYLRRVEELGEEFTGAPLAIELQLPPAGAARPARAAAPAAAAQPRPAAA
                     PARSIAAEAARETAPPGAVSADAETTTVEAEPVAEAPQEPARARRSPPSSSRAEPATG
                     LELAYEKTRLNPDFTFDTLVTGRANDLARAAAMQVAQNPGTSYNPLFVYGGVGLGKTH
                     LVHAIGNAVFRHNPRAVIRYVHVEDYYADVVRAYQQKSFDAFKRYYRSLDMLIIDDIQ
                     FFNNKNRTQEEFFHAFNALTEARKQIVITCDTYPKDIQGLEDRLISRFDWGLTVQIEP
                     PELEMRVAILKKKAEALRVLVDDDVAFLIAKNLRSNVRELEGALNKVVAYARFHGRQI
                     GLEVAKEALKDLLHAHNRQLSIEHIQKTVADYYKIKIADMHSKKRTRVIARPRQVAMW
                     LAKELTPMSLPAIGEAFGGRDHTTVLHACRTITELRLGDAQLNHDVHVLTQVLRG"
     gene            11207..11341
                     /gene="rpmH"
                     /locus_tag="P5537_12535"
     CDS             11207..11341
                     /gene="rpmH"
                     /locus_tag="P5537_12535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011289924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HRV78909.1"
                     /translation="MKRTYQPSVVRRKRTHGFLVRMKTRGGRAVIRARRAKGRHRLAV
                     "
     gene            11343..11705
                     /gene="rnpA"
                     /locus_tag="P5537_12540"
     CDS             11343..11705
                     /gene="rnpA"
                     /locus_tag="P5537_12540"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HRV78910.1"
                     /translation="MVSPTGADQGFRSAHRLHKTDEYSSVFAFRRALRGRFYMVHYRP
                     NELDTARLGVVVAKKLAKRANVRNLVKRIAREIFRRQRTELPAMDLVVRLNAPVAKAT
                     RAELNLDLLSLLQRLPRQ"
     gene            11702..11911
                     /gene="yidD"
                     /locus_tag="P5537_12545"
     CDS             11702..11911
                     /gene="yidD"
                     /locus_tag="P5537_12545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004329522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HRV78911.1"
                     /translation="MKTVLIALLRFYRYAISPMLGRNCRFHPTCSEYAIEAVQRHGAL
                     RGGWMAAKRVGRCHPFNPGGYDPVP"
     gene            11932..>12269
                     /gene="yidC"
                     /locus_tag="P5537_12550"
     CDS             11932..>12269
                     /gene="yidC"
                     /locus_tag="P5537_12550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0051205 - protein insertion into membrane
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HRV78912.1"
                     /translation="MDQRRLILFLIFSFSLVMLWDGWIKHNQPPAAQQQAAAGNAAPA
                     DGAVPTPTLSATPGQPVVPGEQASQAAAAPRTVVETDLLRAEVSAQGGDIVRLELKQH
                     KASGEAGGNFV"
BASE COUNT         1941 a         3669 c         4373 g         2286 t
ORIGIN      
        1 agcgctcgga cgggaatctt gatgcctacc ctttgcgggc cgaaatgaat ccgacgcggg
       61 tcaagctgac cgaaggcgat ctgattcgga tttacttggc ctatttgact gatctggccg
      121 tttctcaggt tcagacttgg tcggcggaag acacgaaagg tccgctctgc cgctatgtga
      181 ggcggcgatt tgcgcatccg tgctggccgt cttcggcgca gaagtcttgg gcggaccggt
      241 tgatgcgcca ctggatggcc gaagcgcaaa ttcttgcgga tacctttcac gatcggtggc
      301 agggcggcct ggatgtggca gaggttaagg cggctgtcga tctagtgcgc gccttggagc
      361 ggcgccccga gtatttgatc gccgacggtg tccccgagcc tgtggccgtg gcggctggag
      421 cgctggtcga cggtgaagac aagcgtcttc ctttcatggt gatcgatgta ggagcaggca
      481 cgaccgactt cggcctcttc ctcctccgcg aggatgagca gcgagagatc acacgggtgt
      541 ttcaggtgcc gggctcgatc aaggccctaa tgcaggccgg cgatcggatc gacatgatgc
      601 tgaagaagtt catcctggat gcccagggtg tcgacctgac cgagccgcac ggtcggctgg
      661 ttgcagccga tctgagccgt cgcatacgtg gattgaagga gcgtttgttt gcggacacca
      721 gggtccagta cgtgcttagc gacggtacgc tcggaaagat cgaactgggc gacttcatgg
      781 cttcgcggcc ggtcagggag ttttccgagc gtgtcgagca gggcttcagg gatgtgctcg
      841 aagggctaca cgacacgtgg ctgagctatc tcaccaagac cgatctcacg gtgattctga
      901 cgggtggcgg cgcaagtctg ccgatgatgc gcgcgctggc cgaggggtgg gtagaagtgc
      961 gcggcaagcg gatcgcacgc aagctcgtga atccgttacc gagctggatt ttgggcgaga
     1021 gcccggagtt ggagcctgtc tatccgcagc tggcagtggc gattggcggc gcggcacatg
     1081 aacttccgga gactgtggat ggccccgaag cctttgccgg tggtgggggc agaacagcgt
     1141 atgcggtagg gaacctgcag gtgagtgggg cctagaccaa gttgagtcaa gaatattggc
     1201 ggtatcgaag ttgccgacgc gacgtgctgc tgcagcttca tgggagatga tggggatgag
     1261 tttgaagccg tggcgcgaaa tcgccgttcc acacgaggac gtgctcaagg gcaccttcca
     1321 gcaggccgag ttcgcggccg acctgtcgcg tgtgcatctg ggcacggcga ccgccgagta
     1381 ccaggacccg tcgctgttct tccagcgcac cttcatcacc gaaggcatgc gcctgctgct
     1441 ggattcggtg gtgcatcgcc tgaccgggcg cggtggcgat ccggtgatcc agttgcagac
     1501 cgccttcggt ggcggcaaga cgcacacgat gctggctgtg tatcacttgg ccaaaggcga
     1561 ggtgtcggct tccgacatgc ctggcattcc gtcgatcctg aacgcggccg gcgtggtgga
     1621 gatgccgcgg gcgcgcatcg cggtgctcga cggcatccgc ctgtcgccca accagccgat
     1681 gaagcgcgat gggctggcgg tgaacacgct ctggggcgag ctggcttggc aactcggtgg
     1741 tgccgagggc tacgccatgg tgcgcgaggc ggacgagtcc ggcacctcgc ccggcaaggg
     1801 cgtgctggcg gatctacttg gccgctacgc accctgcgtg atcctgatcg acgagctggt
     1861 ggcctatatc cgccagttcg aggaaggcaa gacgctgtcg ggcggctcct tcgactcgaa
     1921 cctgagcttc ttgcaggcgc tgaccgaggc gctcaaggcg gtgccgacgg cggtgttgct
     1981 ggcctcgctg cccgagtccg acaaggaagc cggcagccag cgcggcgtga aggcgttggc
     2041 tgccctgtcg cactacttcg ggcgggtcca ggcgctgtgg aagccggtgt cgtccgaaga
     2101 agccttcgag atcgtgcgtc gtcggctttt ctcgagcatc ggcgacaagc tgggcgccga
     2161 gacggtatgc cgggcctttg ccgactacta catcgccaac gctgccgacc tgccgcacga
     2221 gacccaggag gcgcgttact tcgagcgcct gatgcacgcc tacccgatcc atcctgaggt
     2281 gttcgtgcgc ctgtacgagg actggtcctc gctcgacaac ttccagcgca cccgcggcgt
     2341 gctgaagctg atggcgaaga tcatccaccg gctgtggaag gacaacaatt ccgatctgct
     2401 gatcatgccg ggcagcctgc cgctgtacga cgccgacacc cgcaacgaat cgatctacta
     2461 cctgccgcag ggctgggacc cggtgctgga aagcgacgtc gacggcgagc gcgcggagac
     2521 gaccgagctg gagagcgtgg atacccgcct gggcagcgtc caggcgtgcc ggcgcacagc
     2581 gcggacgatc ttcctgggta gtgcgccaac gacatccagc cagatggtgc gcggcatcga
     2641 gctcgagcgg gtattgctgg ggtgcgtgca gccggggcag cagatcggcg tgttcaagga
     2701 cgcgctgcgc cgcctgaacg accgcctgca ctatctgaac tcgggcaaca accgcttctg
     2761 gttcgacacc cggcccaacc tgcgccgcga gatggaagac cgcaagcggc gcttccatga
     2821 caaggacgac gtgatccctg ccgtccgcga ccgcgtgcag cgcaccctgg cgccgggggt
     2881 gttcggcggc gtgcatgtgt tcaccgccag cgccgacatt cccgacgact gggcgctgcg
     2941 cctgatcgtg ctgccgccga cggccggcta cagccgcagc ggcgatcaat cggcgattcg
     3001 ttacgccacg gagatcctca agcaccgcgg cgagcagccg cgcttcaagc agaaccgcct
     3061 catcttcctg gcccccgatg ccgatagcgt gagccgcctg aaggatcagg tgcgctcggt
     3121 gctggcttgg cagtcgatcg tcgccgacat caaggacctc aagctcaacc tcgaccagta
     3181 ccaagcccgg caggccagcc gcagcctgga cgacgctaac gaggctctgc gcggaatggt
     3241 gaaggagagc taccgctgga tgctggcacc ggcccagttc gctgagcgcg gcaaggggct
     3301 ctcggaactg cagtgggaag ccttccagat caactccggc gcgcagaacc tgacgcagga
     3361 gatcgagcgc gtgctgcgcg agaacgagct gctgatcacg gagtgggcgc cgatccacct
     3421 gcacaacgtg ctgaagacgt ggttctggaa ggacggtact ggcgaggcca atgcgctcaa
     3481 cgtctggcag cagacctgcc accagctgta cctgccgcgc ctgaaggacg acgctgtgtt
     3541 ccaccacacg cttgctgcgg gtgccgagag ccgggatttc tttggtttcg cgcaaggcaa
     3601 ggaggacggt cgctacctgg gcttcagctt cgcgaagcgg acaacgccca ttctggacac
     3661 cgcgctgatc ctgatcgaac catcacttgc acacgccgag gccgagcgca tcgcggccga
     3721 acgcgcgcag gaggcggcgg gcgctgcagc ggtgacctat ccgcttggca caccgcccag
     3781 tgcgcaacag gccgccgact ccggcgccac cacgcgcgtt gtcgctactc cagtcgcggc
     3841 aaccactgcg ccacggacac acttcttcgg gacaatcgac ctcgatcccg tcatggcgaa
     3901 gcggcagttc gccgacatca tcgacgaggt ggtgctgaac ttcaccgcga agccgggcgt
     3961 gaaagtgcgg atctcgatcg agatcgacgc cgagagcgaa gcgggcttcg aggatgggct
     4021 gcagcgcgcc gtaagggaga actgcaacgt gttgaggttc aagaacgcgg aattcgattg
     4081 agcccgatcc ctgaaccgat cgacgcccgg gagcgcgctg tcgagctcag ttcggcgaca
     4141 gctgcgtcct gctccggttc gcaccgggac gaacgtcagc gtcgcggcac tgacttcata
     4201 acgagacaag aaaatgcttt ctgaacttgg tttgagcgtg gcccgttcca tccccgtcga
     4261 gcaggtgatt ggtttggcga cgggcaacct gagccttcac ggtggggtga tccgggacgc
     4321 tgcaggtcga atcgtctccc acttggcaat gccggcttct gctggcctgc ttggtgcggt
     4381 tccaggcttg ggcgcgatcg ggtcggtcgt gaccggaatc cagatgcaag ccttgagcgc
     4441 gaacgtggct gcagtgaagg cggcgaccga tcagatcctg aactactcga tcgcgaccac
     4501 cgcgctgtcg ggcttgggta tcgtcacctc ggtaactggc ttcgcctatc ttgcttctcg
     4561 cctgaaccgc atcgacaagc ggctgagcac tcttgagaag cagacgaaag ccatcaagca
     4621 gttcctgcag tcttcgcagc atgcccagct catgaccgcg gtcgatcacc tgcgtctgtc
     4681 tcagcaggcc acggatggcg agacgcggcg acacttgctc cttcagagca agcagctgtt
     4741 cacgaccctg gcccatcact acaaggtcca gctcggggag atcgacgaca tcaccgaact
     4801 gaatgcgacg gaggactgct acgtcctcgc ctgcctcggc agcgtgatgg cgatgagcga
     4861 ccttggcatg ggtgaggccg cccgggatga aatgcttcgc cactacgccg actggcgtgt
     4921 gatcgctcgc aagcactgcg gcaagctgct gctcaaggat gaccctgcac gcctgtttga
     4981 cgcccggtac gtgcagtcgg tgccggccgc aaacctgatt cgcttcctcg acttcacgaa
     5041 cgacagcaac cgcggcgtgc agtggtttga cgagttacgg cgaactcttg acaaggccac
     5101 actggtccgc agcgcgatgt cagtcgtcga gcccgcctgc atcgagtacg cgaacaaact
     5161 gctggtcaag aacgaggtgc tgcagggctt caacgcccat atggggttcc tggccgagaa
     5221 gaagctatcg ctctcgtact ttgcccagag ggtcgaggag atccgggaac gagagggcgc
     5281 gaagttcctg gtgctgcaga acaccgcgcc tgcgtagctg ctcggtcggc ctgccacttg
     5341 gcctcacaga ggaggtccct ctgaaaaggc tgcctctgcg gtgaaagaac aagggcgcct
     5401 acgtttccgc cggcgccctc tggctctcgt gtggcagtag gtcaatttca ccgttcttga
     5461 gaaatctatt tcaccgatgt gagaaaaatt tcagaacgag tgagaaccta cagccgctac
     5521 aaaaatcaca catcgatgtt ctgcgcatac agcgcattgc cttcgatgaa cgcccttctc
     5581 ggctccacgt tatcccccat cagcgtggtg aagatctcgt cggcggcgat cgcgtcgtcg
     5641 atctgcacgc gcagcaggcg gcgcacggcg gggtccatgg tggtctccca cagctgctcg
     5701 gggttcatct cgcccaggcc cttgtagcgc tgcttgctga ggccgcgctc gacctcgccg
     5761 agcagccagc cgatggcgtc ggcgaagcgg gtgacggact ggcgcttctc gccgcggcgg
     5821 atctcggcgc cggggccgat gaggccgctg atggcttcgg cggcgttgcg gatgctgcgg
     5881 tagtcgccgg aaacgaggaa gtcctgctcg acccagccga acttgcggtt gccgtggtgc
     5941 aggcgctcga tggtgaggcg ccagccttcg gactcgtcgt ggtactcggc gtagatctgc
     6001 aggccttcgg gcaggtgggg ctggatgcgc tcggccgagg cacgggcggc ggcctcgtcc
     6061 tccaggctga cctcgagatc gtgggcgagc atgacctgca gcacctcggg gtcgatgtag
     6121 ctggccaggc gcttgatgac ggcttcggcg agcaggtagc tgcgcgcgag gccgccgagg
     6181 gcctcgtcgg cgatcgggct ggcgccttcg cgcggcacca gcatggcgcc gtcgagggcg
     6241 agcttgagca ggtggccgtt gagctcggtg tcgtccttga tgtagatctc ggtcttgccg
     6301 tgcttgatct tgtacagcgg cggctgggcg atgtagatgt ggccgcgctc gaccagctcg
     6361 ggcatctggc ggtagaagaa ggtgagcagc agggtgcgga tgtgggcgcc gtcgacgtcg
     6421 gcgtcggtca tcaggatgat gcggtggtag cgcagcttct cgggcttgta gtcgtccttg
     6481 ccgatgctgg tgccgagggc ggtgatcagg gtggcgatct cctggctctg cagcagcttg
     6541 tcgaagcggg ccttctcgac gttgaggatc ttgcccttga gcgggaggat cgcctggaac
     6601 ttgcggtcgc ggccctgctt ggccgagccg cctgcggagt cgccctcgac gaggtagagc
     6661 tcgcacagcg cggggtcctt ctcctggcag tcggcgagct tgccgggcag gccgacgccg
     6721 tcgagcacgc ccttgcggcg tgtcatctcg cgggccttgc gggcggcgtc gcgggcacgg
     6781 gcggcctcga cgatcttgtt gcagatggtc ttggcgtcga tcgggttctc gagcaggaag
     6841 tcgccgagct tgctggcgac gacctcttcg accgccgggc gggcttccga cgagaccagc
     6901 ttcatcttgg tctggctggc gaacttgggg tcgggcatct tgaccgagag cacgcaggcg
     6961 aggccttcgc gcatgtcgtc accggtgatg tcgaccttgg ccttcttggc gatctcgttt
     7021 tcttcgatgt acttgttgat gacgcgcgtc atcgccgcgc gcaggccggt gaggtgggtg
     7081 ccgccgtcgg cctgcgggat gttgttggtg tagcacagca cctgttcctg gtagctgtcg
     7141 ttccactgca tggcgacctc gaccgcgagc tcggcgtcgt ggccgtggcc ggtggggatg
     7201 cgggtggtgc cggtggcgta gaagacgttg gggtgcagca ccgtcttggc gcggttgatg
     7261 tactcgacga agcccttgac gccgccggcg aaggcgaagt cttcttcctt gccggtgcgc
     7321 tggtcgatga ggcggatctt gacgccgttg ttgaggaagg agagctcgcg caggcgcttg
     7381 gcgaggatgt cgtagtggta ctcgacggtg ccgaagatct cctcgtcggc gaggtagtgc
     7441 accttggtgc cgcgcttggt ggtctcgccg atgacgcgcg ccgggctgac ctcgacgccg
     7501 tcgacgagct cgatgacgcg gttctgcggc ttgccgcgct cgaactcgag caggtggcgc
     7561 ttgccgtcgc gggcgacggt gacgttcatc cacttcgaca gcgcgttgac gcaggacacg
     7621 ccgacgccgt gcaggccgcc ggagaccttg tagctgttct ggttgaactt gccgccggcg
     7681 tgcagcacgc acatgacgat ctcggcggcg ctgcgcttgg gctcgtgctt gtcgtccatc
     7741 ttgacgccga ccgggatgcc gcggccgttg tcggtgaccg agatcgagtt gtcggcgtgg
     7801 atggtgatga cgatgtcgtc gcagtggccg gccagggcct cgtcgatgga gttgtcgacg
     7861 acctcgaaca ccatgtggtg caggccggtg ccgtcggagg tgtcgccgat gtacatgccg
     7921 gggcgcttgc gcacggcttc cagcccttcg agctgctgga tgctggattc gtcgtagtcg
     7981 ttgcccgctt gcggggccgg cgtgttttgc ggttcggaca tggtcatctc ggtgattcgt
     8041 aaagaacggg tgctgcggtg gtgcgggcgg tgcgggtgcc cgtgggggcg gcggatgctg
     8101 cgagccttgt gccgtcggcg ccgggtggtc tggcgctggc gtatgaaggt tcgcggctgc
     8161 cgccgctcct acagggggtc agatgcgcat cggcatcacg acgtacttga acttctcgtt
     8221 gcccggcagg gtgatcaggg cgctggagtt gccgtcgttg aagcgccagt cgaccgtctc
     8281 ggaactgagg ttgttgagca cgtcgagcag gtaggtgacg ttgaagccga tgtcgagctt
     8341 gtcgccctgg tagtcgatct cgagctcgtc catggcctct tcctgctcgg cgttggtcga
     8401 cacgatgcgc aggacgccgt cttcgagcac catgcgcacg ccgcggaact tctcgttggt
     8461 gaggatggcg gcgcgctgca gggcggccag cagcggctgg cgggcgaagc tgaccagctt
     8521 gggatgcgcg gtcgggatca cgcgctcgta gtcggggaac ttgccgtcga tgagcttggt
     8581 gacgagctcg atcgggccga agcggaacac ggcctggttg ccggcgagca ggatctcgag
     8641 cgggtcgtcg ctgtcggcga gctggcgggc gagctcgagc accgtcttgc gcggcaggat
     8701 ggcctcggtg cgctgtgcgt gctgggcgtc gagcggcgcg tcgaggtcgg aggcggcgta
     8761 ggcgaggcgg tggccgtcgg tggcgaccat gcgcagctcg ctgccttcgg cgatcagcag
     8821 caggccgttg aggtagtagc ggatgtcctg ctgcgccatc gcgtaggcca cctgggcgag
     8881 ctggcgcttg aaggcgcgct ggccgatggt gagccgggcg ccagcgtcct cgggcgggtt
     8941 caggcgcggg tagtcggcgg cgggcagggt ctggagctgg aagcggctgc gcccggcctt
     9001 gacggtgagg cgcttgtcgt cgagcgtcag cgagatctcg gcggagtcgg gcagggcgcg
     9061 caggatgtcc tgcagcttgc gcgcgcccac ggtgatcgag gcgtcctcgc cgccgatgtg
     9121 gccgccggtg gtggtgcgga tctggatctc gatgtcggtg gcgagcatcg tgagctggtc
     9181 ggcgtgcttc tcgatcagca cgttcgacag gatgggcagg gtgtggcgct tctcgacgat
     9241 gccggcgacc gactgcagcg gggccaggag cgcatcgcgg gtggtggtga gcaggagcat
     9301 ggcgtcagat cgggtcgatg ggttgatcgg aagtgttcgg tggattggcg ttcaggcggc
     9361 tcagccgcgc aggacctggg tgagcacgtg gacgtcgtgg ttgagctggg cgtcgccgag
     9421 gcgcagttcg gtgatggtgc ggcaggcgtg cagtacggtg gtgtggtcgc ggccgccgaa
     9481 ggcctcgccg atcgcgggca gcgacatcgg cgtgagctcc ttggccagcc acatcgccac
     9541 ctggcgcggg cgcgcgatga cgcgcgtgcg cttcttggag tgcatgtcgg cgatcttgat
     9601 cttgtagtag tcggcgacgg tcttctggat gtgctcgatg gagagctggc ggttgtgcgc
     9661 gtgcagcagg tccttgagcg cttccttggc gacctcgagg ccgatctggc ggccgtggaa
     9721 gcgcgcgtag gcgacgacct tgttgagcgc gccctcgagc tcgcgtacgt tcgagcgcag
     9781 gttctttgcg atcaggaagg cgacgtcgtc gtcgaccagc acgcgcaggg cctcggcctt
     9841 tttcttgagg atggcgacgc gcatctcgag ctcgggcggc tcgatctgca cggtgaggcc
     9901 ccagtcgaag cgcgagatga ggcggtcttc caggccctgg atgtccttcg ggtaggtgtc
     9961 gcaggtgatg acgatctgct tgcgcgcctc ggtgagcgcg ttgaaggcgt ggaagaactc
    10021 ttcctgcgtg cggttcttgt tattgaagaa ctggatgtcg tcgatgatca gcatgtcgag
    10081 cgagcggtag tagcgcttga aggcgtcgaa gctcttctgc tgataggcgc gcaccacgtc
    10141 ggcgtagtag tcctcgacgt gcacgtagcg gatgaccgcg cgcgggttgt ggcggaacac
    10201 cgcgttgccg atcgcgtgca ccaggtgggt cttgccgagg ccgacgccgc catagacgaa
    10261 cagcgggttg taggacgtgc ccgggttctg cgccacctgc atggcggcgg cgcgggcgag
    10321 gtcgttggcg cggccggtga ccagggtgtc gaaggtgaag tcggggttga gccgggtctt
    10381 ctcgtaggcg agctcgaggc cggtggcggg ctcggcgcgg ctgctggagg gcgggctacg
    10441 gcgcgcgcgc gcgggctcct gcggtgcttc ggccacgggc tcggcctcga ccgtggtggt
    10501 ctcggcgtcg gcgctgacgg cgccgggcgg tgcggtctcg cgtgcagctt cggctgcgat
    10561 gctgcgggcg ggtgcggcag cggggcgggg ctgcgcagct gcggcggggg ccgcggcgcg
    10621 cgccgggcgg gcggcgccgg cgggcggaag ctgcagctcg atggcgagcg gggcgccggt
    10681 gaattcctcg ccgagttcct cgacacggcg caggtagcgc tcgcgcaccc actgcagcac
    10741 gaagcggttg ggcgcgacga gcgcccagcc gccttcgccg ggttcggccc gcagggtctt
    10801 gatccaggtg ttgaactgct gctggggcag ctcctgctca aggcgcgaca ggcagaagga
    10861 ccagaaatct tgagtcacgg cgtgggcttg ggatcgtgga gtggcgtgcg gcaggatggc
    10921 gggcaaacgt gtggtggttc ggtctgcggc aatgttcagg gtgcccggcg cccgcaggcg
    10981 cgcgccggga tgcgatacga gttggggagg tgtgccggcg gtgcgctcga gcggcgcact
    11041 gtgcgcgtct cgtccggggc atgggcacct ggagagcgtg gcacgaaaag acagcattct
    11101 aaaccgccac gggagactta tccacaggcg tggtcaaaaa ttcctattga caaacatggg
    11161 attatccatt taactctcgc gtttgaccta acactggcag tccaacatga aacgcactta
    11221 tcagccctcc gttgtccgcc gcaagcgcac ccatggtttc ctggtccgca tgaagacccg
    11281 tggcggccgt gcggtcatcc gcgcacgccg tgccaagggt cgtcaccgcc tcgccgtctg
    11341 aggtggtttc gcccacgggc gctgaccagg gtttccgcag cgctcacaga ttgcacaaaa
    11401 cggatgagta ttcatccgtt tttgcttttc ggcgggcgct gcgcgggcgg ttctacatgg
    11461 tgcattaccg gcccaacgaa ctcgataccg cccgcctcgg cgtggtggtg gcgaagaagc
    11521 tggccaagcg cgccaacgtg cgcaacctcg tcaagcggat cgcgcgcgag atcttccggc
    11581 gccagcgcac cgagctcccg gcgatggatt tggtcgtgcg cctgaacgcg ccggtggcca
    11641 aggccacgcg cgccgagctc aacctcgacc tgctctccct tctgcaaagg ctgccccggc
    11701 aatgaagacg gtgttgatcg ccctgctgcg tttctaccgc tacgcgatca gcccgatgct
    11761 tggccgcaat tgccgcttcc accccacctg ttccgagtac gcgatcgagg ccgtgcagcg
    11821 ccacggcgcg ctgcgtggcg gctggatggc cgcgaaacgg gtggggcgct gtcatccctt
    11881 caatccgggc gggtatgatc ccgttccctg acctgagaca gaacgattcc gatggatcaa
    11941 cgccgcctca tcctctttct gattttctcc ttctcgctgg tcatgctgtg ggatggctgg
    12001 atcaagcata accagccgcc agccgcccag cagcaggccg cagcgggcaa cgcggcgccg
    12061 gccgacggcg cggtgcccac gcccacgctg agcgcgacgc ccggccagcc ggtcgttccg
    12121 ggtgagcagg cttcgcaagc tgcggccgcg ccgcgcacgg tggtcgagac cgatctgctg
    12181 cgcgccgagg tctcggcgca gggcggcgac atcgttcgcc tcgagctcaa gcagcacaag
    12241 gcgagcggcg aggcgggcgg caacttcgt
//
LOCUS       DAOTIN010000093        12269 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_6172_length_12269_cov_8.895857, whole genome shotgun sequence.
ACCESSION   DAOTIN010000093 DAOTIN010000000
VERSION     DAOTIN010000093.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 12269)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 12269)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12269
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6172_length_12269_cov_8.895857"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..>1094
                     /locus_tag="P5537_12555"
     CDS             <1..>1094
                     /locus_tag="P5537_12555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011238854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HRV78913.1"
                     /translation="TGKNLGYGSAAPVERGQLVMDLRRMNRILDVDAELCTALVEPGV
                     TYQQLYDYLQEKKLPLWFSCPAPSVIAGPLGNMVDRGVGYTPYGEHFLFSSGMEVVLA
                     DGEVLRTGMGSMPGSNTWQVFKWGYGPTLDGIFTQSNYGIVTKMGMWLMPAPPDYRPF
                     LIQYPEDTDITKIVDALRPLRIAMVIPNAVVIAHTLWEAPCNKVNRADYHPGPGAISD
                     EAVKKIRKDHNLGAWNVYAALYGTPETNAANWKIIEQVAAATGGTLVTDSTEQGGRAT
                     QYRFDLMKGKPNLGEFDLYNWRGGGGSMWFAPVSQAKGSETLKQMQLAKGILAKYGFD
                     YVGEFIVGWRDMHHVIDLLYDRSDAEQMKKA"
     assembly_gap    1095..1194
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <1195..2478
                     /locus_tag="P5537_12560"
     CDS             <1195..2478
                     /locus_tag="P5537_12560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HRV78914.1"
                     /translation="WAATGPGERRALLMKAAHALEARAEAFTAAMAAETGASAIWAGF
                     NVHLAAGMLLEAAALTTRIEGSILPSDVPGSVAMAVRQPAGVVLGIAPWNAPVILGVR
                     ALATPLACGNTVVLKGSELCPATHGLIIEALQDAGLPAGVVNFVTNAPADAGAVVEAM
                     VAHPALRRVNFTGSTHVGRLIAQTCAKYLKPAVLELGGKAPFVVLDDADLDAAVAAAT
                     FGAFANSGQICMSTERIIVDAAVADDFVARLAARAQGLPLGDPRKGPVVLGSVVDQRT
                     VERCNALIDDALAKGAKLVCGGKADSTLMPATLLDNVSAQMRIYHEETFAPVKAIVRV
                     HGTEAAIACANDNPFGLAAAVFGRDLARAWQVAGRIQSGICHINGPTVHDEAQMPFGG
                     VKDSGWGRFGGQAGIEAFTELRWITMQTSPRHYPF"
     gene            2545..3477
                     /locus_tag="P5537_12565"
     CDS             2545..3477
                     /locus_tag="P5537_12565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004385847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HRV78915.1"
                     /translation="MNKQLRNAILVALGALTAGTASAKEGGDQYPNGIETWFAGAVPP
                     PGNYFINYLGHYGGDLYNGEGKRVAGTSASAWFNAFRFVKVSNIKVLGGDWAGHVILP
                     VVHQRLNLARGSASASGLGDLTIDPFIVAWHKGDWHWTVGLDINLPTGRYKSGDPRKS
                     IGANYWSIEPIFAFTWLSQGGWEVSAKLMYNIKGGNDDYRATPGAAKQKYDSGDDFHM
                     DYLVGRRFGPWGVGLSGYYLKQTGDDKVDGEVIDALPGVWSRGRRGEVLAAGPSLTYS
                     TKGGTMLIAQWQHEFERENRFGGDKALFKLVMPF"
     gene            3733..4947
                     /locus_tag="P5537_12570"
     CDS             3733..4947
                     /locus_tag="P5537_12570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HRV78916.1"
                     /translation="MRPPPNMNHRDRFLELQALLASHDTLWRPPAFQAGLPPWCAERP
                     ALTAELRALDEATLEHLVQDPDDALRWLAPHLPALVRGAELCALPPLPARALPEPDRR
                     LDAGVPGRKRAQIEAFAAHLPAVGLPLLEWCAGKGHLGRRLALADDVPVRSLEIDPAL
                     CAAAERLAGRSRARQQVVCADALDPASRPHLQGHAVLALHACGELHRSLVRAADRDGA
                     PAYAIAPCCYHRGADGGYRPLGPESRLALDAATLRLAVTETVTAPRHDRRRLVRDQAW
                     KLGFIALRQAIEGGPVPSFRPVPPAWLNGRFEDFCRHLAEREGVRLPTAVDWADWEAV
                     GERRRDEVRRLELVRHAFRRALEVWLALDLVLGFEARGFTTRIGTFCERTLTPRNLLV
                     LARRRGAGTLQP"
     gene            complement(4938..6197)
                     /locus_tag="P5537_12575"
     CDS             complement(4938..6197)
                     /locus_tag="P5537_12575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004316694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp70 family protein"
                     /protein_id="HRV78917.1"
                     /translation="MTQPPRACGIDFGTSNSTVGWLRPDAPVLVPLEDGRATLPSAVF
                     FNADEDSIHYGRAALAEYLEGYEGRLMRALKSLLGTSLIDGQTDVNGRALGFRELLAS
                     FIGELKARAERATGRAFDHAVFGRPVHFVDEDEAADRKAQDTLEAIARQVGFREVGFQ
                     FEPIGAALHYERTLSREELVLIADIGGGTADFSIVRLSPQRARAAERREDLLGNAGIH
                     IGGTDFDRVLSLDCVMPVLGYRSRLRNGATMPASVYFQLAAWHTINFAYTRQAWADLQ
                     QVYRDALARTELDRLCRLINLREGHWLAMQVEEAKIALSAAERTQVALARIEPGLALD
                     LSRAAFTAATQGLVDRVGGCVAELLAASGVERERIDTVYFTGGASGVPQLRARIAAEL
                     PRARSVEGDLYGSIGAGLAVEAARRYG"
     gene            complement(6368..7561)
                     /locus_tag="P5537_12580"
     CDS             complement(6368..7561)
                     /locus_tag="P5537_12580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant NAGGN system M42 family
                     peptidase"
                     /protein_id="HRV78918.1"
                     /translation="MNDLARGRHLPAIDYAYLEETMLQLLAIPSPVGLTDAAVRYTAG
                     RFEALGIPYEITRRGAIRATLKGQAAQPARAVVAHLDTLGAMVKALKPNGRLEIVPIG
                     HWSARFAEGGRLTIFTDHGQARGTCLPLKTSGHAFGGEIDTQPVGWEHVEVRVDLPTE
                     DRAGLEAAGIEVGDWIAFDPQPEIQPGGYINSRYLDDKAAVAALLTACKAIRDHGLPL
                     PVDVHPLLTITEEIGSGASAALHGEIAEMVSLDISIAAPGQNTSEHAATICMQDMSGP
                     FDYHLTHKLIALAKEHGIAHRRDIFRYYRSDSAAAVEAGNDIRTALIGFGADASHAQE
                     RTHRDALEALTQLVIAYLTSEPVARRDCRSMGSIEGFTEQLCPGDMAVPATPLPAPES
                     FLGER"
     gene            complement(7678..9432)
                     /gene="ngg"
                     /locus_tag="P5537_12585"
     CDS             complement(7678..9432)
                     /gene="ngg"
                     /locus_tag="P5537_12585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglutaminylglutamine synthetase"
                     /protein_id="HRV78919.1"
                     /translation="MIRKHIARALRAEQRSAQLAVHRPAGQPEPAGAPTDVVVECGWG
                     RLLPAQTWRDAASLAEALLTERPGQRDIAFYVEKPHVVVAHAPQQLFLDPSEAFRLNL
                     ATYRGAPQRAGRSGFTLRRLRTRADVAAINVLYRARRMVPVDAQAVWKARASRAISYA
                     LAEDRASGEVIGVAMGLDHVEAFADPQHGASLWALAVAPQAAHPGVGEALVRYLAEHY
                     QARGREWMDVSVLHDNEQAIALYDKLGFQRIPAFAVKRRNAINEPLFIGGGEALQDLN
                     PYARLLVDEAIRRGIHAEVIDADNGYFRLTLGGRSIVCRESLSELTSAVAMSRCQDKR
                     VTLKLLAGEGLAVPRQADADDEAGWHALLAEVGTVVVKPVEGEQGKGISVDLRSVEDV
                     RAAIERARQFCDRVLVEQFCKGEDLRIVVIDHQVVAAAVRRPPEVVGDGRSTVRELIE
                     RQSRRRAAATGGESRIPLDAEAARCIAAQGHDLDSVLLPDCRLQVRNTANLHTGGTIH
                     DVTAELHPALREAAEKAARALDIPVTGLDFLVPAVDGPDYVIIEANERPGLANHEPQP
                     TAERFIDLLFPRSRAATA"
     gene            complement(9445..11217)
                     /locus_tag="P5537_12590"
     CDS             complement(9445..11217)
                     /locus_tag="P5537_12590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglutaminylglutamine amidotransferase"
                     /protein_id="HRV78920.1"
                     /translation="MCGIAGELRFDDTPPDLAALARMNAQQQARGPDSGGIFAQGAQA
                     WGHRRLKIMDLSESAQQPMFDPALGLGIVFNGAIYNHPELRRELEAKGYRFYSHGDTE
                     VLLKAYHAWGEDFVSRLNGMFAFAIWERDSGRVLLGRDRLGIKPLYYAPIAGGLRFAS
                     ALPALLAAGGVDTSIDPAALNHYLSFHAVVPAPHTLLAGVRKLAPGTLMRIEPDGRRS
                     ERSFWALDYARDAADESRSFEDWTEILLDGLRAAVRRRLVADVPVGALLSGGVDSSLI
                     VGLMAEAGVKELRTYNVGFADVGGEKGNEFEYADIVAREFGTVHERIFVPEQELLTRL
                     PEAVAAMNEPMVSHDCIGFYLLSEAVSRHSKVVQSGQGADEVFGGYHWYPKLAGSADP
                     VADYLAAFRDRDYAEYLATVNPQWHGVDASAAFVAASFNAPGADDPVEKALRLDTTVM
                     LVDDPVKRVDNMTMAFGLEARVPFLDHALVELAARIPARHKLAHGGKGVLKEAARKLI
                     PDAVIDRPKGYFPVPALKYLQGPVLERVRDALSSQSARERGLFRKDYVDTLLADPSAH
                     ITPLRGSKLWQLGLLEWWLQTHVG"
     gene            11352..11858
                     /locus_tag="P5537_12595"
     CDS             11352..11858
                     /locus_tag="P5537_12595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020649406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MaoC family dehydratase"
                     /protein_id="HRV78921.1"
                     /translation="MNPTDTAPLTSRFPTPIDDRYFEDYVPGAVHRFGEMRVTEQEIV
                     DFARRYDPQDFHTDPAKAAGTIFGGLIASGWMTCGMMMRMYSEHYLTHNASLASPGID
                     ELRWLKPVRPDDVLSTRVTIVEARRSVSKPDRGLVRSRIEVLNQRDEVVLSMLAMNLI
                     GCRNPSAN"
     gene            complement(11881..>12269)
                     /gene="arfB"
                     /locus_tag="P5537_12600"
     CDS             complement(11881..>12269)
                     /gene="arfB"
                     /locus_tag="P5537_12600"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="alternative ribosome rescue aminoacyl-tRNA
                     hydrolase ArfB"
                     /protein_id="HRV78922.1"
                     /translation="LSPDEVEITAIRAQGAGGQNVNKVSNAVHLRFDIAASSLPEEIR
                     ARLLQLRDQRISKDGVVIIKAQKFRSLEKNRAEALRRLEELIERVAAPPKDRRPTRPT
                     RASVTRRLEGKARRASVKAARGRVND"
BASE COUNT         1726 a         4406 c         4302 g         1735 t
ORIGIN      
        1 accggcaaga acctgggcta cggctcggcc gccccggtcg agcgcggcca gctggtcatg
       61 gacctgcgcc gcatgaaccg catcctcgac gtcgatgccg agctgtgcac cgcgctcgtc
      121 gagcctggcg tgacctacca gcagctctac gactacctgc aggagaagaa gctgccgctg
      181 tggttctcct gccccgcgcc ttccgtgatc gccggcccgc tcggcaacat ggtcgaccgc
      241 ggcgtgggct acacgcccta cggcgagcac ttcctgttct cgtccgggat ggaggtggtg
      301 ctcgccgacg gcgaggtgct gcgcaccggc atgggctcga tgcccggctc gaacacctgg
      361 caggtcttca agtggggcta cggcccgacg ctggacggca tcttcaccca gtcgaactac
      421 ggcatcgtca ccaagatggg catgtggctg atgccggcgc cgcccgacta ccgccccttc
      481 ctgatccagt acccggaaga caccgacatc accaagatcg tcgacgctct gcgcccgctg
      541 cgcatcgcga tggtgatccc caacgcggtg gtgatcgccc acacgctgtg ggaggcgccc
      601 tgcaacaagg tcaatcgcgc cgactaccac ccgggcccgg gggcgatcag cgacgaggcg
      661 gtgaagaaga tccgcaagga ccacaacctc ggcgcctgga acgtatatgc cgcgctctac
      721 ggcacgccgg agaccaacgc ggcgaactgg aagatcatcg agcaggtggc cgcggccacc
      781 ggcggcacgc tggtcaccga ctcgaccgaa cagggcgggc gcgccaccca gtaccgcttc
      841 gacctcatga agggcaagcc caacctgggc gagttcgacc tctacaactg gcgcgggggc
      901 ggcggctcga tgtggttcgc gccggtgtcg caggccaagg gcagcgagac gctcaagcag
      961 atgcagctgg ccaagggcat cctcgccaag tacggcttcg attacgtggg cgagttcatc
     1021 gtcggctggc gcgacatgca ccacgtcatc gacctgctct acgatcgcag cgatgccgag
     1081 cagatgaaga aggcnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1141 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnntgggcc
     1201 gccaccggcc ccggcgagcg ccgcgcgctg ctgatgaagg cggcgcatgc gctcgaggcg
     1261 cgcgccgagg cctttaccgc ggcgatggcc gccgagaccg gcgcctcggc gatctgggcc
     1321 ggcttcaacg tgcacctggc ggccggcatg ctgctcgagg cggcggcgct gaccacccgc
     1381 atcgagggca gcatcctgcc ctcggacgtg cccggctcgg tggcgatggc ggtgcgccag
     1441 cccgccggcg tggtgctcgg catcgcgccc tggaacgccc cggtgatcct gggcgtgcgt
     1501 gcgctcgcca ccccgctcgc ctgcggcaac accgtggtgc tcaagggctc ggagctgtgc
     1561 ccggccaccc acggcctgat catcgaggcg ctgcaggacg ccgggctgcc ggcgggcgtg
     1621 gtgaacttcg tcaccaacgc cccggccgac gccggcgcgg tggtcgaggc catggtcgcg
     1681 cacccggcgc tgcgccgggt gaacttcacc ggctcgaccc acgtcggccg cctgatcgcg
     1741 cagacctgcg cgaagtacct caagccggcg gtgctcgagc tcggcggcaa ggcgcccttc
     1801 gtggtgctcg acgacgccga cctcgacgcc gcggtggcgg cggccacctt cggcgccttc
     1861 gccaactcgg ggcagatctg catgtcgacc gagcgcatca tcgtcgacgc ggcggtggcc
     1921 gacgacttcg tcgcccgcct cgcggcgcgc gcgcagggcc tgcccctggg cgacccgcgc
     1981 aaggggccgg tggtgctcgg ctcggtggtc gaccagcgca cggtcgagcg ctgcaacgcg
     2041 ctcatcgacg acgccctcgc caagggcgcg aagctcgtct gcggcggcaa ggccgacagc
     2101 acgctgatgc ccgccacgct gctcgacaac gtcagcgcgc agatgcgtat ctaccacgag
     2161 gagaccttcg ccccggtaaa ggcgatcgtg cgcgtgcacg gcaccgaggc cgccatcgcc
     2221 tgcgccaacg acaacccctt cggcctcgcc gccgcggtgt tcggccgcga cctggcgcgc
     2281 gcctggcagg tggccggacg catccagtcg ggcatctgcc acatcaacgg gccgacggtg
     2341 cacgacgagg cgcagatgcc cttcggcggc gtcaaggact cgggctgggg acgcttcggc
     2401 ggccaggccg gcatcgaggc cttcaccgag ctgcgctgga tcacgatgca gacgagcccg
     2461 cgccactatc cgttctgaga cgcccgcggc ccagggggct gcggcccgca tcgcacatac
     2521 cgaaaagaac agggaggaga cctcatgaac aagcagcttc gcaacgcaat cctcgtcgcg
     2581 ctcggcgcgc tcaccgcggg cacggcgagc gccaaggagg gcggagacca gtacccgaac
     2641 gggatcgaga cctggttcgc cggcgcggtg ccgccgccgg gcaactactt catcaactac
     2701 ctcggccatt acggcggcga cctctacaac ggcgagggca agcgcgtcgc cggcacctcg
     2761 gcgagcgcct ggttcaacgc cttccgcttc gtcaaggtca gcaacatcaa ggtgctgggc
     2821 ggggactggg cgggccacgt gatcctgccg gtggtgcacc agcgcctgaa cctcgcccgc
     2881 ggcagcgcct cggcgagcgg gctgggcgac ctcaccatcg accccttcat cgtcgcctgg
     2941 cacaagggcg actggcactg gaccgtggga ctggacatca acctgccgac cgggcgctac
     3001 aagtcgggcg atccgcgcaa gagcatcggc gccaactact ggagcatcga accgatcttc
     3061 gcctttacct ggctgtcgca gggcggctgg gaggtctcgg ccaagctgat gtacaacatc
     3121 aagggcggca acgacgacta ccgcgcgacc cccggcgcgg cgaagcagaa atacgactcc
     3181 ggcgacgact tccacatgga ctacctcgtc gggcgccgct tcggcccctg gggcgtgggc
     3241 ctgtcgggct attacctcaa gcagaccggc gacgacaagg tcgacggcga ggtcatcgac
     3301 gcgctcccgg gcgtgtggtc gcgcgggcgc cgcggcgagg tgctcgcggc cggtcccagc
     3361 ctgacctact cgaccaaagg cggtacgatg ctgatcgcgc agtggcaaca cgagttcgag
     3421 cgcgagaacc gcttcggcgg cgacaaggcc ttgttcaagc tggtgatgcc gttctagtgt
     3481 ggccgggggc ggcggattgg cccgaagctt ggcggttcgc gccttccggc gctcctacaa
     3541 gggcccgtcg cgggctggac gcgctgtagg agcgccggaa ggcgcgaacc gtcgccccca
     3601 cacgccgggc gacgcgattc gcccaccgac acgagcgaca cgagcgcgag cgcccccaca
     3661 cacccggcga cgcgatgggt cgcacgcccg ccggcgcccc ctaccccctc tgcccgccgg
     3721 agcgcgcagc ccgtgcgccc tcccccaaac atgaaccacc gcgaccgctt cctcgaactg
     3781 caggccctgc tcgccagcca cgacaccctg tggcgcccgc ccgccttcca ggccggcctg
     3841 ccgccctggt gcgccgagcg gccggcgctc acggccgagc tgcgcgcgct cgacgaggcc
     3901 acgctcgagc atctggtgca ggatccggac gacgccctgc gctggctcgc cccccacctg
     3961 cccgcgctgg tgcgcggcgc cgagctgtgc gcgctgccgc ccctgccggc gcgcgcgctg
     4021 cccgagcccg accgccgcct cgacgccggc gtgcccggtc gcaagcgggc gcagatcgag
     4081 gccttcgccg cgcatctgcc cgccgtcggc ctgccgctgc tggagtggtg cgcgggcaag
     4141 ggccacctcg gccgccgcct ggcgctcgcc gacgacgtgc cggtgcgttc gctggagatc
     4201 gacccggccc tgtgcgcggc ggcggagcgg ctcgccgggc gcagccgcgc acgacagcag
     4261 gtggtgtgcg ccgacgcgct cgaccccgcc tcgcgccccc acctgcaagg ccacgcggtg
     4321 ctcgcgctgc acgcctgcgg cgagttgcac cgcagcctgg tgcgcgccgc cgaccgcgac
     4381 ggcgcgcccg cctacgccat cgcgccgtgc tgctaccacc gcggcgcaga cggcggctat
     4441 cgcccgctcg gacccgagtc ccgcctcgcg ctcgacgccg cgaccctgcg cctggcggtg
     4501 accgagaccg tgaccgcgcc gcgccacgac cgccgccggc tcgtccgcga ccaggcctgg
     4561 aagctcggct tcatcgccct gcgccaggcc atcgagggcg gccccgtgcc cagcttccgc
     4621 ccggtgccac cggcctggct gaatggccgc ttcgaggact tctgccgcca cctcgccgag
     4681 cgcgagggcg tgcgcctgcc gacggcggtg gattgggccg attgggaggc cgtcggtgag
     4741 cgtcggcgcg acgaggtgcg ccgcctcgag ctggtgcgcc acgccttccg gcgcgcgctc
     4801 gaggtgtggc tcgcgctcga cctcgtgctc ggcttcgagg cgcgcggctt cacgacacgc
     4861 atcggcacct tctgcgagcg cacgctgacg ccgcgcaacc tgctggtcct cgcccgccgg
     4921 cgcggcgcgg ggacgcttca gccgtagcgc cgcgccgcct cgaccgcgag gccggcgccg
     4981 atgctgccgt acaggtcgcc ctcgacgctg cgcgcccgcg gcagctcggc cgcgatgcgc
     5041 gcgcgcagtt gcggtacgcc gctcgccccg ccggtgaaat agacggtgtc gatgcgttcc
     5101 cgctccacgc ccgaggcggc gagcagctcg gccacgcagc cgccgacgcg atcgaccagg
     5161 ccctgcgtcg ccgcggtgaa ggccgcgcgc gaaagatcga gcgccagccc gggctcgatg
     5221 cgcgcgagcg ccacctgcgt gcgctccgcc gcggacagcg cgatcttggc ctcctccacc
     5281 tgcatcgcca gccagtgccc ctcgcgcagg ttgatgagcc ggcacaggcg gtcgagctcg
     5341 gtgcgcgcga gcgcgtcgcg gtagacctgc tgcaggtcgg cccaggcctg gcgggtgtag
     5401 gcgaagttga tcgtgtgcca ggcggcgagc tggaagtaca cgctcgccgg catcgtcgcc
     5461 ccgttgcgca ggcggctgcg gtagccgagc accggcatca cgcagtccag gctcaggacg
     5521 cggtcgaagt cggtgccgcc gatgtggatg cccgcgttgc cgaggaggtc ctcgcggcgc
     5581 tcggcggcgc gcgcgcgctg tggcgacagg cgcacgatgg agaagtcggc cgtgccgccg
     5641 ccgatgtcgg cgatcagcac cagctcctcg cggctgaggg tgcgctcgta gtgcagcgcg
     5701 gcgccgatcg gctcgaactg gaagccgacc tcgcgaaagc ccacctggcg cgcgatggcc
     5761 tcgagcgtgt cctgggcctt gcggtcggcg gcctcgtcct catcgacgaa gtgcaccggg
     5821 cggccgaaca ccgcgtggtc gaaggcgcgc ccggtcgcgc gctcggcacg cgccttgagc
     5881 tcgccgatga agctcgcgag cagctcgcgg aagccgagcg cgcgcccatt cacgtcggtc
     5941 tgtccgtcga tcaggctggt gccgagcagg ctcttgagcg cgcgcatcag gcggccttcg
     6001 tagccctcga ggtattcggc gagcgccgcg cgcccgtagt ggatcgagtc ctcgtcggcg
     6061 ttgaagaaca ccgccgaggg cagcgtcgcc cgcccgtcct cgagcgggac gaggacgggc
     6121 gcgtcggggc gcagccagcc gacggtggag ttggaggtgc cgaagtcgat gccgcaggcg
     6181 cggggaggct gggtcatggg gtcgctcgcg ggacgggacg cgctcggtgc gcacaaacgg
     6241 ggaggcggcg attatgcgtc ccgacgggct cgcgcgcgac tgttggagcg gaccaggccg
     6301 ctcccacggt cgcgcacgtc acgcctgccg ttcgcgcgca ggcgcggttc cccggggccg
     6361 gcgccgatca gcgctccccg aggaaactct cgggcgccgg gagcggcgtg gcgggcaccg
     6421 ccatgtcgcc cgggcagagc tgctcggtga aaccttcgat cgagcccatc gagcggcagt
     6481 cgcgacgcgc caccggctcg ctggtcaggt aggcgatgac gagctgggtg agcgcctcga
     6541 gcgcgtcgcg gtgggtgcgc tcctgggcgt gcgaggcgtc ggcaccgaag ccgatcagcg
     6601 cggtgcggat gtcgttgccc gcctccaccg cggcggccga gtccgagcgg taatagcgga
     6661 agatgtcgcg gcggtgggcg atgccgtgct ccttggcgag cgcgatcagc ttgtgggtga
     6721 ggtggtagtc gaaggggccc gacatgtcct gcatgcagat cgtcgccgca tgctccgagg
     6781 tgttctgccc gggcgcggcg atggagatgt ccaggctcac catctcggcg atctcgccgt
     6841 gcagcgcggc cgaggcgccc gagccgatct cctcggtgat ggtgagcagc ggatgcacgt
     6901 ccaccggcag cggcaggccg tggtcacgga tcgccttgca ggcggtgagc agcgccgcca
     6961 ccgcagcctt gtcgtcgagg tagcgcgagt tgatgtagcc cccgggctgg atctcgggct
     7021 gggggtcgaa ggcgatccag tcacccacct cgatccccgc cgcctccagc ccggcgcggt
     7081 cctcggtggg caggtccacc cgcacctcga cgtgctccca gcccaccggc tgggtgtcga
     7141 tctcgccccc gaaggcgtgg cccgaggtct tgagcggcag gcaggtgccg cgcgcctggc
     7201 catggtcggt gaagatggtg agccgccctc cctcggcgaa gcgcgccgac cagtggccga
     7261 tgggtacgat ctcgagccgg ccgttgggct tcagcgcctt caccatcgcc cccagcgtgt
     7321 cgaggtgggc caccaccgcg cgcgccggct gcgcggcctg gcccttgagc gtggcgcgga
     7381 tggcaccgcg acgggtgatc tcatagggga tgccgagcgc ctcgaagcgc cccgcggtgt
     7441 agcgcaccgc ggcgtcggtc aggccgaccg ggctggggat ggcgagcagc tgcagcatcg
     7501 tctcctccag gtaggcgtag tcgatcgcgg gcaggtgcct gcctcgggcc aggtcgttca
     7561 tggggtcgtc tcctctcttg tcggtggatt gggcgcgcca cgggggtggc gcgcgcggag
     7621 ggtgtcagcc gcaggctgct cgtgggcttg cccgcgaggg cggcgacatc ggcgcgatca
     7681 ggccgtcgcc gcgcgcgagc gcgggaacag caggtcgatg aagcgctctg ccgtgggctg
     7741 gggttcgtgg ttggccaggc ccgggcgctc gttggcctcg atgatcacgt agtccgggcc
     7801 atcgaccgcg ggcacgagga agtccagccc ggtcaccggg atgtcgagcg cacgcgcggc
     7861 cttttcggcg gcctcgcgca gcgccggatg cagttcggcg gtgacgtcgt ggatggtgcc
     7921 gccggtgtgc aggttggcgg tgttgcgcac ctgcaggcgg caatcgggca acagcacgga
     7981 atcaagatcg tgcccttgcg ccgcaatgca gcgggctgcc tcggcatcca gcgggatgcg
     8041 cgactcgccg ccggtggctg ccgcgcgccg ccggctctgg cgctcgatca gctcgcgcac
     8101 ggtgctgcgc ccgtccccca ccacctccgg tggccgccgc actgccgcag ccacgacctg
     8161 atgatcgatg acgacgatgc gcaggtcctc gcccttgcag aactgctcga cgagcacgcg
     8221 atcgcagaac tgacgcgcgc gctcgatcgc ggcgcgcacg tcctccacgc tgcgcagatc
     8281 gacactgatg cccttgccct gctcgccctc gaccggcttg accaccaccg tgccgacctc
     8341 ggcgagcagc gcgtgccagc cggcctcgtc gtcggcatcg gcctggcgcg gcaccgcgag
     8401 cccctcgccg gcgagcagct tcagcgtcac gcgcttgtcc tggcagcggc tcatcgccac
     8461 cgcgctggtg agctcggaca gggactcgcg gcagacgatg ctgcgcccgc ccagggtgag
     8521 acggaagtag ccgttgtcgg catcgatgac ctcggcgtgg atgccgcgtc ggatcgcctc
     8581 gtccaccagc aggcgggcgt aggggttgag atcctgcagt gcctcgccac cgccgatgaa
     8641 cagcggctcg ttgatcgcgt tgcggcgctt gaccgcgaac gcggggatgc gctggaagcc
     8701 gagcttgtcg tagagcgcga tcgcctgctc gttgtcgtgc agcaccgaca cgtccatcca
     8761 ctcgcgcccg cgcgcctggt agtgctcggc gagatagcgc accaacgcct cgcccacgcc
     8821 cgggtgcgcc gcctgcggcg ccaccgcgag cgcccacagg ctggcgccgt gctgcgggtc
     8881 ggcgaaggcc tcgacgtggt cgaggcccat cgccacgccg atcacctcgc cgctggcgcg
     8941 gtcctcggcg agcgcgtagc tgatcgcccg gctggcgcgc gccttccaca ccgcctgcgc
     9001 atccaccggc accatgcggc gcgcgcggta gagcacgttg atcgccgcca cgtcggcgcg
     9061 cgtgcgcagc cgccgcagcg tgaagccgct gcgcccggcg cgctgcgggg cgccgcggta
     9121 ggtggcgagg ttgaggcgga aggcctcgga cggatcgagg aagagctgct gcggcgcatg
     9181 cgccacgacc acgtgcggct tctcgacgta gaaggcgatg tcgcgctggc cggggcgctc
     9241 ggtgagcagc gcctcggcca ggctcgcggc gtcgcgccag gtctgcgccg gcagcagccg
     9301 cccccagccg cattcgacga cgacgtcggt gggcgcgccc gccggctcgg gctggccggc
     9361 ggggcgatgc acggccagct gcgcgctgcg ctgctcggca cgcagcgcgc gggcgatgtg
     9421 cttgcggatc atcgtgcctt gtcctcagcc cacgtgggtc tgcagccacc actccagcag
     9481 ccccagctgc cagagcttgg agccgcgcag cggcgtgatg tgggcggacg ggtcggcgag
     9541 cagcgtgtcg acgtagtcct tgcggaacag cccgcgctcg cgcgccgact ggctggacag
     9601 cgcgtcgcgc acgcgctcga gcaccggccc ctgcaggtac ttgagcgccg gcaccgggaa
     9661 gtagcccttg gggcggtcga tcaccgcgtc ggggatcagc ttgcgcgccg cctccttcag
     9721 cacgcccttg ccgccgtgcg cgagcttgtg gcgcgccggg atgcgcgcgg cgagctcgac
     9781 cagcgcgtgg tcgaggaagg gcacgcgcgc ctccaggccg aaggccatgg tcatgttgtc
     9841 cacgcgcttg accgggtcgt cgaccagcat caccgtggtg tccaggcgca gcgccttctc
     9901 caccgggtcg tccgcgccgg gggcgttgaa gctcgccgcg acgaaggccg cgctcgcatc
     9961 gacgccgtgc cactgcgggt tcaccgtggc gaggtattcg gcgtagtcgc ggtcgcggaa
    10021 ggcggcgagg tagtccgcca ccgggtcggc gctgccggcg agcttcgggt accagtggta
    10081 gccgccgaag acctcgtccg cgccctgccc gctctgcacc accttgctgt ggcgcgacac
    10141 ggcctcggag agcaggtaga agccgatgca gtcgtggctc accatgggct cgttcatcgc
    10201 cgccaccgcc tcgggcaggc gggtgagcag ttcctgctcg ggcacgaaga tgcgctcgtg
    10261 caccgtgccg aactcgcgcg cgacgatgtc ggcgtattcg aactcgttgc ccttctcgcc
    10321 gcccacatcg gcgaagccga cgttgtaggt gcgcagctcc ttcacccccg cctcggccat
    10381 caggccgacg atgaggctgg aatcgacgcc gcccgagagc agcgcgccca ccggcacgtc
    10441 cgccaccagg cgacgcctga ccgcggcgcg caggccgtcg agcaggatct cggtccagtc
    10501 ctcgaagctg cgtgactcgt cggcagcgtc gcgggcatag tccagcgccc agaagctgcg
    10561 ctcgctgcgt cggccgtcag gctcgatgcg catcagcgtg cccggggcga gcttgcgcac
    10621 gccggccagc agcgtatgcg gcgccggcac cacggcgtgg aaggagaggt aatggttgag
    10681 cgccgccggg tcgatcgagg tgtccacccc gcccgccgcg agcagcgccg gcagcgccga
    10741 ggcgaagcgc agcccgcccg cgatcggcgc gtaatacagc ggcttgatgc ccaggcggtc
    10801 gcggccgagc agcacgcgcc cgctgtcgcg ctcccagatc gcgaacgcga acatgccgtt
    10861 gaggcggctg acgaagtcct cgccccaggc gtgataggcc ttgagcagca cctcggtgtc
    10921 gccgtgggag tagaagcggt agcccttggc ctcgagctcg cggcgcagct cggggtggtt
    10981 gtagatcgcg ccgttgaaaa cgatgcccaa ccccaacgcc ggatcgaaca tcggctgctg
    11041 ggcggactcg gacagatcca tgatcttcag ccggcgatgg ccccaggcct gcgcgccctg
    11101 cgcaaatatg ccgccactgt ccgggccgcg cgcctgctgc tgcgcgttca tgcgcgccaa
    11161 agccgcaagg tccggggggg tgtcatcgaa tctcagctca cctgcaattc cacacattga
    11221 atttcctggt ccggtttcaa tgcctcctat tctatcaaat ttgttttgta caaatattcc
    11281 aacgtctgat gccccgcccc ggaccggctt cgggctacca tcgatccgag ccaccacacg
    11341 aacaggacac catgaacccg accgacaccg cgcccctcac gagcaggttt cccaccccga
    11401 tcgacgaccg ctacttcgag gactacgttc ccggcgccgt gcatcgcttc ggcgagatgc
    11461 gcgtcaccga gcaggagatc gtcgatttcg cacgccgcta tgacccgcag gatttccaca
    11521 ccgaccccgc aaaggccgcg ggcaccatct tcggcggcct gatcgccagc ggctggatga
    11581 cctgcgggat gatgatgcgg atgtactcgg agcattacct cacccacaac gccagcctcg
    11641 cctcgcccgg catcgacgag ctgcgctggc tcaagccggt gcgtccggac gacgtgctga
    11701 gcacgcgggt caccatcgtc gaggcacgac gttcggtctc caagcccgac cgcggcctgg
    11761 tgcggtcgag gatcgaggtg ctcaaccagc gcgacgaggt agtcctgagc atgctcgcga
    11821 tgaacctgat cggctgccgt aaccccagcg cgaactgacc gaggctctgc ggcgcgccgc
    11881 tcagtcgttc acccggccgc gcgcggcctt caccgacgcc cgccgcgcct tgccctcgag
    11941 ccggcgggtg acggaggcgc gcgtcggccg cgtcgggcgg cggtccttgg gcggcgccgc
    12001 gacgcgctcg atcagctcct ccagccggcg cagcgcctcg gcgcggttct tctccaggct
    12061 gcggaacttc tgcgccttga tgatcacgac gccgtccttg ctgatgcgct ggtcgcgcag
    12121 ctgcagcagt ctcgcccgga tctcctcggg caggctggag gcggcgatgt cgaagcgcag
    12181 atgcaccgcg ttcgacacct tgttgacgtt ctggcccccg gcgccctggg cgcggatcgc
    12241 ggtgatctcg acctcatcgg gggagagtg
//
LOCUS       DAOTIN010000094        12205 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_6213_length_12205_cov_8.856872, whole genome shotgun sequence.
ACCESSION   DAOTIN010000094 DAOTIN010000000
VERSION     DAOTIN010000094.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 12205)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 12205)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12205
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6213_length_12205_cov_8.856872"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(153..989)
                     /locus_tag="P5537_12605"
     CDS             complement(153..989)
                     /locus_tag="P5537_12605"
                     /inference="COORDINATES: protein motif:HMM:NF012257.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HRV78923.1"
                     /translation="MNRIHHCLDMARTDDCASCLLEGSAACGSITALASVAGGVPFVC
                     HVFAPGEALYRSGEPVDGLHFIVSGGVKLVRCDAAGHERIVHFAQDGGIVGFDAINGE
                     ASQHGAIALDEVRTCCIPADKLVRVLARRPALQMQVLRQMQRALSDAHGWIAELASGV
                     LPARVRLARLLLRLRCGEGERIRRLQLTEIGSILAQTPETVCRTLKAFEQDGVLVPQG
                     GRGSQRHYLADLAALQRIAHEGAEGLPIAARAPAGDDVELARPPRSRRGEAALRRAAA
                     TH"
     gene            complement(1083..3065)
                     /locus_tag="P5537_12610"
     CDS             complement(1083..3065)
                     /locus_tag="P5537_12610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_function: GO:0005375 - copper ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent copper receptor"
                     /protein_id="HRV78924.1"
                     /translation="MNRIFKRLPLAVAVSMALPVLAQAQETRLGSVVVTAPVTEAPLT
                     VTTDPKAPRQPLPAHDGADMLKSIPGFSVIRKGGTDGDPVFRGMSGSRLGILLDGQEI
                     HGGCGGRMDPPTAYIYPEAYDRVTVLKGPQSVLYLPGSSAGVVLFERDIQRMSEPGWS
                     AQGSLTFGSFGRNDQYLEARGGNPDFYARANATRSDSDNYEDGDGKEVHSFYTRWSTS
                     AALGWTPDDHTLIELSAGRSDGEAAYADRAMDGTKFERENVGLKFEKRNVSALVNKVE
                     ANVYYSYIDHVMDNYSLRANKGMKMLNNPDRETKGGRVAVTLTPTESVQVVLGADMKT
                     DEHTFRDGTNYYSKPRTGDLSFDRYGVFGEATYALDDVRRVIGGLRLDDHEVTNDKMG
                     GVKESETLPSGFLRFEQDYAGGAGTWYAGLGHAERFPDYWEYMRTGNTIVVPDARTFD
                     TLDSEKTTQLDIGANWTHGEWSASVSGFYSKVDDYILLRWVSDKAANVRNVDATVYGL
                     EGDLAWRFAPNWQAYGTLAWVRGSNDTDDKPLAQQPPLEAKLGVEYDNRVFSYGALLR
                     MVSEQDRYDIGSGSIVANGQDLGPTGGFATLALNAGWRPNKTTLLTAGVDNVFDRTYR
                     EHLGKGGWDFGSAKVTDLRINEPGRTFWLKAQVALD"
     gene            complement(3127..3588)
                     /locus_tag="P5537_12615"
     CDS             complement(3127..3588)
                     /locus_tag="P5537_12615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016531 - copper chaperone activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone PCu(A)C"
                     /protein_id="HRV78925.1"
                     /translation="MQKPLLAAPLLAAFALLGSAVAHAEVTVAEPWVRATVPAQKATG
                     AFMHLKSDADARLVSAASPVAGVVEIHEMFMDKDVMKMSPIPGLDLPAGRDVELKPGG
                     YHVMLMDLKQQVKVGDEVPLTLTIENKDGSRATIELKAAARPLNAPMKMHH"
     gene            complement(3781..4197)
                     /locus_tag="P5537_12620"
     CDS             complement(3781..4197)
                     /locus_tag="P5537_12620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004317831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2946 domain-containing protein"
                     /protein_id="HRV78926.1"
                     /translation="MQRFCRRLHAWIAIFAMAMSALAPAVSRAMGPDEHGRYLVQLCS
                     AAGVEWVELTADEAAFYGETGAVSSESDPAQSAPSLDHCPYCSAQFGSALPPTPALSP
                     SFAVAGGAVLPTLFLVAPQPLFAWSPAHPRAPPARA"
     gene            complement(4274..5578)
                     /locus_tag="P5537_12625"
     CDS             complement(4274..5578)
                     /locus_tag="P5537_12625"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0071111 - cyclic-guanylate-specific
                     phosphodiesterase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing phosphodiesterase"
                     /protein_id="HRV78927.1"
                     /translation="MDSLIPNGFLAALTEVSARLAEIGNEGHGVGVISLYAQPDAALY
                     RLPLEHLRRFERAMERRIRAQLRSRDSLFAVDGKEWLIVLPRVPSSAVLTLGMLRFEQ
                     TFNDSPLAVDGLEAPVRVVCGAAISPDHGKDGFHLLQSARIAGLVAGRADSGSLLFES
                     SMERSAPNVALLERDLRTAFSGGPELELWLQPKVHLASAECRSAEALLRWRNSAGDFV
                     PPPVVVGLIDRLGLRHRFNRWLFQQAAQSLHQLRMEGLEVDVSINLSATDLYDAEVPD
                     LISQALSTWNLEAGRLCLEITETSMMDESAGSNVSEVLHRLRELGVSLSIDDFGTGFS
                     GMSRLKRLAVQEVKIDRSFVIDLLASARDREIAASIIDLSHRLGIEVTAEGVEDADTA
                     ELLAGMGCDYIQGFLHARALPLAEFVAWVRAREGIGRQAAQT"
     gene            complement(5581..6906)
                     /locus_tag="P5537_12630"
     CDS             complement(5581..6906)
                     /locus_tag="P5537_12630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD-GYP domain-containing protein"
                     /protein_id="HRV78928.1"
                     /translation="MSQTISTRELRLGMFVVGIDRPWTETPFMMQGFLLENADQLRAL
                     QKYCRSVTIDRSRSIGDQYSAKVFDKDAALRGADGLVRKHPDVVESRIEAQRFIRVAR
                     SFKGKIHTRRQPHIPRIRSEDGRSRLESELLYSAPIVDDVYRALREAQLAIDGNVAID
                     VPQINGLVGEMAAGVQRNPDALLWLTRLKRTDQYAYDHAVNVSVHAMVFARFVGLSGK
                     QVHQLGLAGLLQDIGKVQIDYGLLGKPGPLDEHEFEHVKAHVTNTVRLLQAHQDFDAE
                     VLAIIGAHHERFDGTGYPRGLEGMSIPLPAEMAGIIDAYCAMTRDRVYREAVSSQRAM
                     ETLNQLRNTQFRDTLVDQFLQCIGLYPIGTLVELNSGEVGVVIQQNQVRRLQPRVLVL
                     LAPDKSVERFPRTLDLLMQPETTAGEPYRIVQALPPNAFGIDPNDFFLA"
     gene            complement(7024..10959)
                     /gene="purL"
                     /locus_tag="P5537_12635"
                     /gene_synonym="purI"
     CDS             complement(7024..10959)
                     /gene="purL"
                     /locus_tag="P5537_12635"
                     /gene_synonym="purI"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011239293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HRV78929.1"
                     /translation="MTSILKLRGAPALSSSRLERLSRAVGEVLPKLAGLAAEHWYFVE
                     VSSSLDEAELARLVDLLDARPASAEAPAGSLRLVVPRLGTISPWSSKATDIAHQCGFD
                     KIVRIERGIAYSIDARGVDGNAALQARLHDRMTESVLSSVNEAEALFHHYQPQPLTTV
                     DILAGGRAALEKANGELGLALSEDEIDYLVENFTRMGRNPTDVELMMFAQANSEHCRH
                     KIFNADWVIDARPMEKSLFGMIKDTHKAHPEGTVVAYSDNASVIEGARIARLYPDADG
                     AFRYHDEDTHILAKVETHNHPTAISPFPGAATGAGGEIRDEGATGRGSRPKAGLAGFT
                     VSNLNIPDFGQPWEKPYGKPERIASALDIMIEGPIGAAAFNNEFGRPNLAGYFRTFEQ
                     AVQGEVRGYHKPIMIAGGLGSIQAQQAEKPTFPPGTLLIQLGGPGMLIGLGGGAASSM
                     ATGTNTADLDFASVQRGNPEIQRRCQEVIDACWQQGDRNPIIAIHDVGAGGLSNAMPE
                     LADHAGLGAHFELREVHIEEPGMSPREIWSNESQERYVIAIAPESLPMFEAFCERERC
                     PFAVLGTATADGHLTVSDRHFGNKPVDMDMKVLLGKPPKMTRNVSRRAVHLPPFDTTG
                     FDLQEAGMRVLRVPAVASKSFLITIGDRSVGGLTARDQFVGPWQVPVADVAVTAMSFQ
                     GYRGEAFAMGERTPLACVDAPASGRMAIGEAITNIAAADIAKLGDVKLSANWMAAAGH
                     RGEDARLFDTVKAVSEFCVAAGLSIPVGKDSLSMRTAWRDGEEDKQVVAPLSLIATAF
                     APVQDIRATLTPQLQLPEGVETELLLIDLGNGKNRLGGSAFAQAYESVGEHAPDVDPA
                     QLAAFFETVQRLRRDGLLLAYHDRSDGGLFATVCEMAFAAKCGLSLILDTVCYDPYMM
                     DVDGLEKKPDTLKGRFDDRLFAGLFAEELGAVIQIRREDRSRITELLRAAKLAYHFIG
                     EPNDKDEIRFRRNAKLVFSASRVELLQAWSETSHRIARLRDDPESAQQEFDALADAAD
                     PGLSVALSFDVREDVAAPFIASGARPKVVVLREQGVNSQFEMAAAFERAGFTPVDVHM
                     SDLQAGRIDLADFHGMAACGGFSYGDVLGAGQGWAKSILFNPRLKDEFAAFFGRGDTF
                     ALGVCNGCQMMAHLAPIIPGAEAWPTFHRNRSEQFEARFVMVEVADSPSILLQGMAGS
                     RMPIVVSHGEGRAVFRSEADRERALLALRYVDNRGNPAQAYPANPNGSPAGVTGFTST
                     DGRFTIMMPHPERTARTLQMSWAPQWLVKDSPDASPWLRMFRNARAWLG"
     gene            11123..11830
                     /locus_tag="P5537_12640"
     CDS             11123..11830
                     /locus_tag="P5537_12640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004317838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HRV78930.1"
                     /translation="MPEINYLWAPPAPVSLPVRGTGARFPVNRLFFVGRNYQAHALEM
                     GTSVDKGSMRPVYFTKSSANLALSGSTAPYPPETHDYHHEMELVVAIGEAGFRVDESA
                     ARRMIYGYGCGLDMTRRDLQAAAKAKGNPWDLAKNVESGAVCGEIQPAGGELLRSGEI
                     VLRVNGEVRQRADLSDMIWSIPEIIADLSTYYHLQPGDLIYTGTPEGVGPVKPGDRLE
                     GSVEGAGKIEFEIGEAE"
BASE COUNT         1960 a         3975 c         4316 g         1954 t
ORIGIN      
        1 gaagtggcgc acggcagctg caccgacctg ccgccgatgc gcaagaagta aggctgtccc
       61 ggcgcttgcc gtcgagtggg ggcgccccgc cggtttccgg cgcgggcgcc tttttcatgg
      121 gtggcgcgaa tgcacgcagg cgccttgccc gctcaatgcg tggcggcggc gcgccgcaac
      181 gcggcctcgc cacggcggct gcgcggcgga cgggcaagct ccacatcgtc cccagccggc
      241 gcgcgtgccg cgatcggcaa accttccgcc ccctcgtgcg cgatgcgctg caaggccgcg
      301 aggtcggcga ggtaatgccg ctgcgacccg cggccaccct gcggcacgag cacgccgtcc
      361 tgctcgaaag ccttcagcgt gcggcacacc gtctcgggcg tctgcgcgag gatggaaccg
      421 atctcggtca gttgcaggcg gcggatgcgc tcaccctcgc cgcagcgcag gcgcagcagc
      481 aggcgagcga gcctcacccg cgccggcagc accccgctcg cgagctcggc aatccagcca
      541 tgagcatcgg acaacgcgcg ctgcatctgg cgcagcacct gcatctgcag cgccggccgg
      601 cgggcgagca cacgcaccag cttgtcggcc ggaatgcagc aggtacgcac ctcgtcgagc
      661 gcgatcgcgc cgtgctggct ggcttcgccg ttgatcgcgt cgaagccgac gatgccgccg
      721 tcctgggcga agtgcacgat gcgctcgtgc ccggcggcgt cgcagcgcac cagcttgacg
      781 ccgccggaga cgatgaagtg caggccgtcg accggctccc cgctgcggta cagcgcctcg
      841 cccggcgcga agacgtggca gacgaagggc accccgcccg cgaccgacgc aagcgcggtg
      901 atcgacccgc aggctgcgga gccttcgaga aggcacgacg cgcagtcgtc cgtgcgcgcc
      961 atatccaggc aatgatggat cctgttcatg ttctcgcccc ccctcgggac gaaggattcg
     1021 atttgccggg ccgcaggcgg agacccctcc ccgcccgcag cccggatgcg gcgcgagcgc
     1081 gctcagtcga gcgccacctg cgccttcagc cagaaggtgc ggccgggttc gttgatgcga
     1141 agatccgtta ccttcgcgga accgaagtcc cagccacctt tgccgaggtg ctcgcgataa
     1201 gtgcgatcga aaacgttgtc gacaccggcc gtcagcaggg tcgtcttgtt cgggcgccag
     1261 cctgcgttga gcgccagggt cgcgaagccc ccggtcggac cgaggtcctg cccgttcgcc
     1321 acgatgctgc ccgagccgat gtcgtaacgg tcctgctccg acaccatccg cagcagcgca
     1381 ccgtaggaga acacacggtt gtcgtactcg acgccgagct tcgcttcgag cggcggctgc
     1441 tgggcgagcg gcttgtcgtc cgtatcgttg ctgccgcgca cccaggcgag ggttccatag
     1501 gcttgccagt tcggcgcaaa gcgccacgcg aggtcgccct ccaggccata cacggtcgca
     1561 tccacgttgc gtacgttggc ggccttgtcg ctgacccagc gcagcaggat gtagtcgtcg
     1621 accttgctgt agaagcccga taccgaggct gaccattcgc catgcgtcca gttcgcgcca
     1681 atgtcgagtt gggtggtctt ctcggaatcg agcgtgtcga aagttcgtgc gtcgggaacc
     1741 acgatcgtat tgccggtgcg catgtactcc cagtaatcgg ggaaacgctc ggcgtggccg
     1801 agcccggcat accaggtacc cgcgccgccg gcgtaatcct gctcgaaacg caggaagccg
     1861 ctgggcagcg tctcgctctc tttcacgcca cccatcttgt cgttcgtgac ttcgtggtcg
     1921 tcgagacgca agccaccgat gacccggcgt acatcatcga gggcgtaggt ggcctcaccg
     1981 aatacgccat agcggtcgaa gctcagatcc cccgtccgcg gcttcgagta gtagttcgtt
     2041 ccatcgcgga acgtgtgctc gtcggtcttc atgtctgcac cgagtacgac ctgaaccgac
     2101 tcagtcggtg tcagcgtcac ggcaacccgg ccgcccttgg tctcgcggtc ggggttgttc
     2161 agcatcttca tgcccttatt ggcgcgaagg ctgtagttgt ccatcacatg gtcgatgtag
     2221 ctgtaataga cattggcctc gaccttgttc accagcgcgg aaacgttgcg cttttcgaac
     2281 ttgaggccga cgttctcgcg ctcaaacttc gtcccgtcca ttgcgcggtc ggcgtaggcc
     2341 gcctcgccgt ccgaacgacc cgcgctaagc tcgatcaggg tatggtcatc cggcgtccag
     2401 cccaaggcgg cactggtgct ccagcgtgtg tagaaggagt gtacctcctt cccgtcgcca
     2461 tcctcgtagt tgtcgctatc ggagcgcgta gcgttggcgc gtgcatagaa gtccggattg
     2521 ccgccacgcg cctccaggta ttgatcgttg cggccgaaac tgccgaaggt gaggctgcct
     2581 tgagcactcc agccgggttc ggacatgcgc tggatgtcac gctcgaagag caccaccccg
     2641 gccgaactgc ccggcaagta aagcacgctc tgcggcccct tcagcacggt cacgcggtca
     2701 taggcctccg ggtagatgta ggccgtgggc ggatccatgc ggccgccgca gccaccatga
     2761 atttcctgcc cgtcgagcag gatgccgagc cgcgagcccg acatcccgcg gaagaccgga
     2821 tcaccgtcgg taccgccctt ccggatcacc gagaagcccg gaatgctctt gagcatgtcg
     2881 gcgccatcgt gcgccggcag gggctggcgc ggggccttgg ggtcggtggt gacggtgagc
     2941 ggcgcctcgg tgacgggggc agtcacgacc acgctgccga gccgggtttc ctgggcctgg
     3001 gcgaggaccg gcaaggccat ggacacggcc acggcgagcg ggaggcgttt gaagatcctg
     3061 ttcatgttgt tttccatttg cttaaaaaga cgtggatgct gcagatgaaa cggggttggc
     3121 ccgcgctcag tgatgcatct tcatcggtgc gttgagcggg cgcgctgcgg ccttgagctc
     3181 gatcgtggcg cggctgccgt ccttgttctc gatcgtcagc gtgagcggga cctcgtcgcc
     3241 gaccttcacc tgctgcttca ggtccatcag catcacgtgg tagccgcccg gcttgagctc
     3301 gacgtcccgg ccggcgggga ggtcgagacc ggggatgggg ctcatcttca tgacgtcctt
     3361 gtccatgaac atctcgtgga tctcgaccac gccggcgacc ggcgaagcgg ccgacacgag
     3421 gcgggcgtcg gcgtcggact tcaggtgcat gaaggcgccg gtagccttct gcgcgggcac
     3481 ggtggcgcgc acccagggct cggcgacggt gacttcggcg tgcgcgacgg cgctgccgag
     3541 gagggcgaag gcggccagca gcggcgcagc caggagcggc ttttgcatcg tggttctccg
     3601 gtggatggag tatcggggtc cgcacggtcg cgcgctggcg cgctccggaa gaggaggcgt
     3661 cgaacacggg cttgcgcgcg ggggactcgc gcgaccggca ggccggcggg cgaggaaggg
     3721 cttcaggcga gggaaaggac cactgcggcg aacgcgtgtg gcgtccgcag gtgcgcaggg
     3781 tcaggcgcgc gcaggcgggg cgcgcgggtg cgcgggcgac caggcgaaga gcggctgcgg
     3841 cgcgacgagg aagagcgtgg gcagcaccgc tccgccggcg acggcgaagg acggcgaaag
     3901 cgctggcgtg ggcggcagcg cgctgccgaa ctgggcggag cagtaggggc agtggtctag
     3961 cgaaggagcg gattgggccg ggtcggattc cgagctcacc gcgccggtct cgccatagaa
     4021 ggcggcctca tcggcggtga gttccaccca ttcgacaccg gctgcagaac acagctggac
     4081 gaggtagcgg ccatgctcgt cgggtcccat cgcccggctg accgccggcg ccagcgcgct
     4141 catcgccatc gcgaagatcg cgatccaggc gtggagacgt cggcagaagc gctgcatgag
     4201 ggaatcggat ccgtggaaac cacaacgatg agcaggatta tacccgatca tcccccgcgt
     4261 aatttgatcg cggtcaggtt tgcgccgctt ggcggccgat gccttcgcgc gcgcgcaccc
     4321 aggcgacgaa ttccgcgagc ggcaaggccc gggcgtgcag gaagccctgg atatagtcgc
     4381 agcccatgcc tgcgagcagt tcggcggtgt cagcgtcctc cacgccttcg gcagtgacct
     4441 cgatgccgag gcggtgcgag aggtcgatga tcgaggcagc gatctcgcgg tcgcgcgccg
     4501 aggcgaggag gtcgatgacg aagctgcggt cgatcttgac ctcctgcacg gcgagccgct
     4561 tgagccggct catgcccgag aacccggtgc cgaagtcgtc gatcgagagc gagacgccaa
     4621 gctcgcgcag ccggtgaagg acctcggaga cgttgctgcc cgcgctctcg tccatcatgc
     4681 tggtctcggt gatctccaga cacagccgcc cggcctcgag gttccaggtc gacagcgcct
     4741 ggctgatcag gtcggggact tcggcgtcgt agaggtcggt ggcggagagg ttgatcgaga
     4801 cgtcgacctc caggccttcc atgcgcagct gatgcaggct ctgcgcggcc tgctggaaca
     4861 gccagcggtt gaaacggtga cgcaggccga ggcggtcgat cagaccgacc accaccggcg
     4921 gcggcacgaa atcgcccgcg ctgttgcgcc agcgcagcag ggcctcggcg ctgcggcact
     4981 ctgcgctggc gaggtggacc ttgggctgca gccagagctc gagctccggc ccgccggaaa
     5041 aagccgtccg caggtcgcgc tcgagcagcg cgacgttggg cgcgctgcgc tccatcgagg
     5101 actcgaagag caggcttccg ctgtctgcac gcccggcaac caggccggcg atgcgcgccg
     5161 actgcagcag atggaagccg tccttgccgt ggtcgggcga tatcgccgcg ccacaaacca
     5221 cgcgcaccgg cgcctcgagc ccgtcgaccg ccagcgggct gtcgttgaag gtctgctcga
     5281 agcgcagcat gccgagcgtg agcaccgcgg agctgggcac ccggggcagc acgatcagcc
     5341 actccttgcc atcgaccgcg aacaggctgt cgcggctgcg cagctgggcg cggatccgac
     5401 gctccatggc gcgctcgaag cggcgcaggt gctcgagcgg aagccgatag agcgccgcgt
     5461 cgggctgggc atagagggag atcacgccga ccccgtgtcc ttcgttcccg atctcggcca
     5521 ggcgcgccga gacctcggtg agtgcggcga gaaagccgtt cgggatcagc gaatccatgt
     5581 tcaggcgagg aagaagtcgt tggggtcgat gccgaaggcg ttgggaggca gcgcctgcac
     5641 gatgcggtag ggctcgccgg cggtggtctc gggctgcatc agcaggtcga gggtgcgggg
     5701 gaagcgctcc acgctcttgt cgggggcgag cagcacgagc acacgcggct gcaatcggcg
     5761 cacctggttc tgctggatca ccacgccgac ctcgccgctg ttgagctcga cgagcgtgcc
     5821 gatcgggtag aggccgatgc actgcaggaa ctggtcgacc agggtgtcgc ggaattgggt
     5881 gttgcgcagc tggttgagcg tttccatggc gcgctggctg gagacggcct cgcgatagac
     5941 acggtcgcgg gtcatcgcgc agtaggcgtc gatgatgccg gccatctctg ccggcagcgg
     6001 gatgctcatg ccctcgaggc cgcgcggata gccggtgccg tcgaagcgct cgtggtgcgc
     6061 gccgatgatc gccagcactt cggcgtcgaa gtcctggtgg gcctgcagca gccgcacggt
     6121 gttggtgacg tgggccttga catgctcgaa ctcgtgctcg tcgagcggac ccggcttgcc
     6181 gagcaggccg tagtcgatct gcaccttgcc gatgtcctgg agcaagccgg cgaggccgag
     6241 ctgatgcacc tgcttgccgc tgaggccgac gaagcgggcg aacaccatcg catgcaccga
     6301 gacgttgacc gcgtggtcgt aggcatactg gtcggtgcgc ttgaggcggg tgagccagag
     6361 cagggcgtcg ggattgcgct gcacgccggc ggccatctca ccgaccagcc cgttgatctg
     6421 ggggacgtcg atggcgacat tgccgtcgat cgcgagctgg gcctcgcgca aggctcggta
     6481 gacgtcatcg acgatcggcg ccgagtagag cagctcggat tcgagccggc tgcgcccgtc
     6541 ctcgctgcgg atgcgcggga tgtgcggctg gcggcgggta tggatcttcc ccttgaagct
     6601 gcgcgcgacc ctgatgaagc gctgcgcctc gatgcgcgac tcgacgacgt cggggtgctt
     6661 gcgtacgagc ccgtccgcac cgcgcagggc cgcgtccttg tcgaagacct tggcgctgta
     6721 ctggtcaccg atcgagcgcg agcgatcgat cgtgaccgag cggcagtact tctgcagtgc
     6781 ccggagctgg tcggcgttct cgagcaggaa accctgcatc atgaacggcg tctcggtcca
     6841 tggacggtcg atgccgacga cgaacatgcc gagcctcagt tcgcgcgtcg aaatcgtctg
     6901 gctcaattca ttcccccaca gtgacgtccg ccatgatcac agaccggaaa atcataacgg
     6961 caggcgtctc gacagcttga gcacaaaatc atgcccgact acccggatcg ggtggtccca
     7021 cgatcagcca agccaggccc gggcgttgcg gaacatgcgc agccagggcg aggcgtcggg
     7081 gctgtccttt accagccact gcggcgccca cgacatctgc agggtacgcg cggtgcgctc
     7141 gggatgcggc atcatgatcg tgaaacgccc atcggtgcta gtgaaacccg tcacgccggc
     7201 cggcgatccg ttgggattcg ccgggtaggc ctgcgccgga ttgccgcggt tatccacgta
     7261 gcgcagggcc aggagggcac gttcgcgatc tgcctcgctg cggaacaccg ccctgccctc
     7321 gccgtggctg acgacgatcg gcatgcggct gccggccatg ccctgcagca ggatcgacgg
     7381 actgtcggcg acctccacca tgacgaagcg cgcctcgaac tgctcgctgc ggttgcggtg
     7441 gaaggtcggc caggcctcgg cgccggggat gatcggcgcg aggtgggcca tcatctggca
     7501 gccgttgcac acaccgagcg cgaaggtgtc gccacgcccg aagaaggccg cgaactcgtc
     7561 cttcagccgc gggttgaaga ggatggactt ggcccagccc tgccccgccc ccagcacgtc
     7621 gccataagag aagccgccac aggccgccat cccatggaag tcggcgagat cgatgcggcc
     7681 ggcctgcagg tccgacatat gcacatcgac cggggtgaag cccgcacgct cgaaagccgc
     7741 cgccatctcg aactgcgaat tgaccccctg ctcgcgcagc acgacgacct tgggccgtgc
     7801 accgctggcg atgaagggcg cggcgacgtc ctcgcgcaca tcgaaggaca gcgccaccga
     7861 caggccaggg tcggcggcgt cggcgagcgc gtcgaactcc tgctgcgccg actcggggtc
     7921 gtcgcgcagc ctggcgatgc ggtggctggt ctcggaccag gcctgcagca gctcgacgcg
     7981 gctggcggag aacacgagct tggcgttgcg ccggaagcgg atctcgtcct tgtcgttggg
     8041 ctcaccgatg aagtggtaag cgagcttcgc cgcgcgcagc agctcggtga tgcgggagcg
     8101 gtcttcgcgg cggatctgga tgaccgcgcc gagctcctcg gcgaagagcc ccgcgaacag
     8161 gcggtcgtcg aagcgaccct tgagggtgtc gggcttcttc tcgaggccat cgacatccat
     8221 catgtagggg tcgtagcaca cggtgtcgag gatcagcgac aggccgcact tcgcggcgaa
     8281 agccatctcg cacacggtgg cgaagaggcc accgtccgag cggtcgtggt aggccagcag
     8341 caggccgtcg cggcgcagtc gctgcacggt ctcgaagaag gccgcgagct gggcgggatc
     8401 gacatccgga gcgtgctcgc cgaccgactc gtaggcctgg gcgaaagccg agccgccgag
     8461 gcggttcttg ccgttgccga ggtcgatgag cagcagctcg gtctcgacgc cttcgggcag
     8521 ctgcagctgc ggggtgagcg tggcgcggat gtcctgcacc ggggcgaagg cggtggcgat
     8581 cagcgacagc ggggcgacga cctgcttgtc ctcttcgccg tcgcgccagg cggtgcgcat
     8641 cgacagcgag tccttgccca ccgggatgga caggccggca gcgacgcaga actcggagac
     8701 ggccttgacc gtgtcgaaga gccgcgcatc ctcgccgcgg tgaccggccg cggccatcca
     8761 gtttgctgac agcttgacgt cgcccagctt ggcgatgtcg gcggcggcga tgttggtgat
     8821 cgcctcgccg atcgccatgc gtcccgaggc cggcgcatcg acgcaggcca gcggcgtgcg
     8881 ctcgcccatc gcgaaggctt cgccgcggta gccctggaag ctcatcgcgg tgaccgcgac
     8941 gtcggccacc ggcacctgcc aggggccgac gaactggtcg cgcgcggtga ggccgcccac
     9001 cgagcggtcg ccgatggtga tcaggaagct cttgctcgcc accgccggca cgcgcagcac
     9061 gcgcatcccg gcctcctgca ggtcgaagcc ggtggtgtcg aagggcggca ggtgaaccgc
     9121 gcgccgcgac acgttgcgcg tcatcttggg cggcttgccg agcagcacct tcatgtccat
     9181 gtccacgggc ttgttgccga agtggcggtc ggacacggtg aggtggccgt ctgcggtggc
     9241 ggtgccgagg acagcgaagg ggcagcgctc gcgctcgcag aaggcctcga acatcggcag
     9301 gctctcgggc gcgatcgcaa tcacgtagcg ctcctgcgac tcgttcgacc agatctcgcg
     9361 cgggctcatg cccggctcct cgatgtgcac ctcgcgcagc tcgaagtgcg cgcccaagcc
     9421 ggcgtggtcg gcgagctcgg gcatcgcgtt cgacaggcca ccggcgccga cgtcgtggat
     9481 ggcgatgatc gggttcctgt cgccctgctg ccagcaggcg tcgatgacct cctggcagcg
     9541 acgctggatc tcggggttgc cacgctgcac cgaggcgaag tcgaggtcgg ctgtgttggt
     9601 gccggtggcc atcgacgagg ccgcaccgcc acccaggccg atgagcatgc ccggcccgcc
     9661 gagctggatc agcagcgtgc cgggggggaa ggtaggcttc tcggcctgct gcgcctggat
     9721 gctgcccagg ccgccggcga tcatgatcgg cttgtggtag ccgcgcacct cgccctgcac
     9781 cgcctgttcg aaggtgcgga agtagcccgc gaggttgggg cggccgaact cgttgttgaa
     9841 cgcagcggcg ccgatcgggc cctcgatcat gatgtcgagc gcggaggcga tccgctcggg
     9901 cttgccatag ggcttctccc agggctggcc gaagtcgggg atgtttaggt tggagacggt
     9961 gaatccggcc aggcccgcct tgggacgcga gccgcggccg gtcgcgccct cgtcgcggat
    10021 ctcgccgccg gcgccggtgg ccgcgcccgg gaagggcgag attgcggtcg ggtggttgtg
    10081 ggtctcgacc ttggcgagga tgtgggtgtc ctcgtcgtgg tagcggaagg cgccgtcggc
    10141 gtccgggtag aggcgggcga tgcgcgcgcc ctcgatcacc gaggcgttgt ccgagtaggc
    10201 gacgaccgtg ccttcggggt gcgccttgtg ggtgtccttg atcatgccga acagcgattt
    10261 ctccatcggc cgcgcgtcga tcacccagtc ggcgttgaag atcttgtgcc ggcagtgctc
    10321 ggagttggcc tgggcgaaca tcatcaactc gacgtcggtg gggttgcgcc ccatgcgagt
    10381 gaagttctcg accaggtagt cgatctcgtc ctcggacagc gccaggccaa gctcgccgtt
    10441 ggccttctcc agcgcagcgc ggccgccggc gaggatgtcc accgtggtga gcggctgcgg
    10501 ctggtagtgg tggaagagcg cctcggcctc atttacgctg ctcagcaccg actcggtcat
    10561 gcggtcgtgc aggcgcgcct gcagggccgc gttgccgtcc accccgcgcg cgtcgatcga
    10621 gtaggcgatg ccgcgttcga tgcgcacgat cttgtcgaag ccgcactggt gggcgatgtc
    10681 ggtggccttg gacgaccacg gcgagatcgt gcccaggcgc ggcacgacga ggcgcaagga
    10741 gcccgcaggc gcctccgcgc ttgccggacg cgcgtccaga agatcgacga ggcgcgcgag
    10801 ctccgcctcg tccagtgagc tagagacctc gacgaaatac cagtgctccg cagccagccc
    10861 agccagcttg ggcaacactt cgccgacggc gcgggaaaga cgttccagac gggaggagga
    10921 cagcgccggg gcgccacgca gcttgaggat cgaagtcatg ttctcgagaa accgggtcgg
    10981 atacgggcag tgcggacaga tgccagagga ggccgcgagg agccctgcgg gactgttcgc
    11041 gggcagtgca acattataac cgagcccctt cggcagtccg ggccgttgta gactcccggg
    11101 ctcgatgagc aagaggcccg aaatgcccga aatcaactac ctgtgggcgc ccccggcgcc
    11161 cgtctccctg cccgttcgcg gcaccggcgc gcgcttcccg gtcaaccgcc tgttcttcgt
    11221 cggccgcaac tatcaggccc atgcgctaga gatgggcacc tcggtggaca agggcagcat
    11281 gcgcccggtg tacttcacca agtcctccgc aaacctcgcc ctctcgggca gcactgcgcc
    11341 ctacccgccc gagacccacg actaccatca cgaaatggaa ctcgtggtag cgatcggcga
    11401 agccggcttt cgtgtggacg agtcggcagc ccgccgcatg atctacggat atggctgcgg
    11461 cctcgacatg acgcgccgcg acctgcaggc cgcagccaag gcgaagggta acccctggga
    11521 cctcgcgaag aatgtggaga gcggcgcggt gtgcggcgag attcagcccg cgggtggcga
    11581 gttgctgcgt agcggagaga tcgtgctgag agtcaacgga gaggtgcgtc agcgtgccga
    11641 tctctccgac atgatctgga gcatcccgga gatcatcgcg gacctgtcca cctactacca
    11701 cctgcagccc ggcgacctga tctacaccgg cacgccggag ggcgtcggcc cggtgaagcc
    11761 gggcgatcgc ctggagggat ccgtggaagg tgcgggcaag atcgagttcg agatcggcga
    11821 ggctgaataa gcccgggcga aaaacctgga aggtccgccg ctgcgcccgc ccggccccac
    11881 cgagaagtgt cttgctcgga gcatgggcgg gcacgaacgc gaggtgccct gactttaggt
    11941 cgtcgctcgt ctggaagcgt tctccatgcg gggcgcgccc ctcgctcctg gatcaacgaa
    12001 gcggcagagc ctcaatgtgg gcgcagcggc aggctcggac cggacggcgc ggcgagcggc
    12061 acagcctccg gagccgatcg gcagcttcgc tgcctcgctg cgctcctgcg gaacgtagcg
    12121 gtctgcgcgg tctgatcgcc atgcgtgacg cgtatacggc gcaacgcccc aggcacgaag
    12181 aggtgcgtgg ggcgttgttt tgtgg
//
LOCUS       DAOTIN010000095        12077 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_6286_length_12077_cov_8.802861, whole genome shotgun sequence.
ACCESSION   DAOTIN010000095 DAOTIN010000000
VERSION     DAOTIN010000095.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 12077)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 12077)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12077
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6286_length_12077_cov_8.802861"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..983)
                     /locus_tag="P5537_12645"
     CDS             complement(<1..983)
                     /locus_tag="P5537_12645"
                     /inference="COORDINATES: protein motif:HMM:NF016724.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HRV78931.1"
                     /translation="MALTLKRYQREALAALARFFALARGARDEAALDAAFRQTLLEQE
                     HAAETIPPYLAQGFVNDDGATPYVCVRIPTGGGKTLLGAHALAAAARHYTGQDRPLAL
                     WLVPTNVIRQQTLSALKTPGHPYREALEAHFGVDGVRVLDIADSDQIRPQDIGARALV
                     IVGTLQTLRVDDTSGRDVYAYKEDFEPHFERAPELPGFERVSERDLEVQPYLGRADLG
                     KVKRSFANLMYWHRPVVIIDEAHNARTPLSYDSFAPLRPAALIEMTATPLRQGRHRSN
                     VLYHVSAEELKAEEMIKLPIVLSAHPNWEEAVRDALLTRTRLAEEAARELAA"
     gene            complement(974..>1579)
                     /locus_tag="P5537_12650"
     CDS             complement(974..>1579)
                     /locus_tag="P5537_12650"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006306 - DNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HRV78932.1"
                     /translation="LDSFLGSGTTAAVAHKMGRRYIGIEMGEHAHTHCLPRLQKVIAG
                     EQGGISKAVDWQGGGGVRFARLGAPVFLPDGQVDPAIGFATLAAWIWYQETRTPWRPQ
                     AADAQPASPLLGVHEGRAYFLLFNGVLGDRRPQGGNVLTSAVAALLDEAAAGAGVAAG
                     TPRVVFGEACRLSEMRRRALGIDFRQIPYDIRARQEAPAWR"
     assembly_gap    1580..1679
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<1680..2080)
                     /locus_tag="P5537_12655"
     CDS             complement(<1680..2080)
                     /locus_tag="P5537_12655"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006306 - DNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HRV78933.1"
                     /translation="MPILDWLNKRQALQAAAAVPYRLIEVDAVHGDPAADNWLIQGDN
                     LDALKALLPFHAGRVKCIYIDPPYNTRSAFEHYDDNLEHSQWLSMMAPRLELLRELLA
                     EDGSIWVSIDDNEGHYLKVLMDEVFGRGNFIA"
     gene            complement(2256..3698)
                     /locus_tag="P5537_12660"
     CDS             complement(2256..3698)
                     /locus_tag="P5537_12660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014237317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HRV78934.1"
                     /translation="MELDWLLAPPLPAAVPRQRVLYLRLREAILSGRLPANTCLPASR
                     SLAATLGIARNTVLFAYEQLVAEGCLVADRQGTRVAPLPAAACAAQPASPAPEASPTL
                     SARAAAALQREPARDAEALPFSPGVPDFGAFPFRAWRACLERAWRDAGWRQLGYAAHG
                     GDPALRAALAAHLTSVRGLAVDAAQILITSGTQAALDLCARLLADHGDTVWVENPGYL
                     AARVAFGLAGLRVHDVAVDAEGLAPGADDWQHRRPRLIMVTPSHQYPTGRVMSLARRL
                     ALIERARAAGAWIVEDDYDSEFRRAGPAPPALFGLHADAPVVYAGTFSKTLYPGLRLG
                     YLVLPRTVADDFIHAAARATRAGQGIEQRALADFIARGHYTTHVRRMRARYNARQAAL
                     RAALQQAFGPGLVLSGGEAGLHLVMWLPDALPDVAVAQRAARLGLGVRALSAYARPPV
                     GCNGLVLGYGNLDEGAVEGAVARLKRAVAG"
     gene            3792..4430
                     /locus_tag="P5537_12665"
     CDS             3792..4430
                     /locus_tag="P5537_12665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HRV78935.1"
                     /translation="MPHTTAPSPRTRVRRLPERAHYDADSIAAIVDAAMLCTVAFQID
                     GMVHAIPTIHWREGGHLYIHGAKGSRMLKALTDGEACVTIALADGLVLARSALHHSMN
                     YRSVVIYGRFEAVTEPAYKLASLRAFIDGLYPGRWDTLRPINDKELNATTVLRIALDE
                     ASAKVRDWGVKDDEEDLEWPVWAGVIPLRTETGAPEIEHDSVGRVVPPTRFG"
     gene            complement(4468..4968)
                     /locus_tag="P5537_12670"
     CDS             complement(4468..4968)
                     /locus_tag="P5537_12670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004312945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78936.1"
                     /translation="MYPIHGTDAQLLLATLIAAKRRPAALTDIVAAAEFMGFPVTAPA
                     AWATAFERFVTHGLLTAVREGYALTPAAVQLVEGLPKKAEADERVFLVRERLAAYKPV
                     GEHAGIGIGAEQFEAALRDHARLAQQGGKNLLMPKPKRDDEDERRRPYGGRPGGGRFG
                     NTRRRP"
     gene            5223..6494
                     /locus_tag="P5537_12675"
     CDS             5223..6494
                     /locus_tag="P5537_12675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002928323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HRV78937.1"
                     /translation="MKLETIAVHGGYSPDPTTKAVAVPIYQTTSYAFDDTQHGADLFD
                     LKVQGNIYTRIMNPTTAVLEQRVAELEGGIGALAVASGMSAITYAIQTIAEAGDNIVS
                     ASTLYGGTYNLFAHTFPQFGIEVRFADYRDPDSFAALIDARTKAIYCESVGNPLGNVT
                     DIGRLAEIAHKAGVPLIVDNTVPSPYLCRPFEHGADIVVHALTKYLGGHGNSIGGAIV
                     DSGKFPWAEHKARFKRLNEPDVSYHGVCYTEALGAAAFIGRARVVPLRNTGAAISPFN
                     SFLILQGIETLALRMDRICTNTIKVAEYLKKHAKVEWVNYAGLPDHADHGLVKKYMGG
                     RASGILSFGVKGGFEAGGRFQDALKLITRLVNIGDAKSLACHPASTTHRQLSPAELAK
                     AGVSPDMVRLSIGIEHIDDIIADLEQALAAV"
     gene            6753..7226
                     /gene="dtd"
                     /locus_tag="P5537_12680"
     CDS             6753..7226
                     /gene="dtd"
                     /locus_tag="P5537_12680"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HRV78938.1"
                     /translation="MLAVLQRVSEARVIVDGETIGEIGPGLLALVCAERGDTPAEADK
                     LLAKMLKLRIFSDEAGKMNRSVQDVEGGLLVVSQFTLAADSSGGNRPSFTNAADPRTG
                     QALYEHFVARARAAHPQVQTGRFAADMKVQLINDGPVTVPLRIAPTGTDNARGLL"
     gene            7400..8005
                     /gene="gstA"
                     /locus_tag="P5537_12685"
     CDS             7400..8005
                     /gene="gstA"
                     /locus_tag="P5537_12685"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione transferase GstA"
                     /protein_id="HRV78939.1"
                     /translation="MKLYLKPGACSLSPHIALEESGLPYETEAVDLKTKVTASGADFW
                     KSNPKGYVPALLLDSGELLTEGAAIVQYIADQAPGKKLAPANGSIERYRLQSWLNFIG
                     SELHKSCSPFFNPASGKEWKEIAGANLERRLGYVNEALEGKPYLMGEDFSVADGYLFT
                     VLSWMKFVGIDLAKWPNLTAFQTRVAARPAVQAVLKAEGLA"
     gene            8182..8556
                     /locus_tag="P5537_12690"
     CDS             8182..8556
                     /locus_tag="P5537_12690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004312939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF423 domain-containing protein"
                     /protein_id="HRV78940.1"
                     /translation="MTDPSSRLPLLAGALLAALGVALGAFGAHALRGALDATAQGWWQ
                     TAVQYQMWHALGLLAIGAARVPGSRLAALLLAAGTLVFCATLYLMALGAPRWLGAITP
                     IGGSLMIAGWLVLAWRVARLRA"
     gene            complement(8570..9121)
                     /locus_tag="P5537_12695"
     CDS             complement(8570..9121)
                     /locus_tag="P5537_12695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004333930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sterol desaturase family protein"
                     /protein_id="HRV78941.1"
                     /translation="MAEPWMLRVALAYPASLAVPCAGLVVLAMNWPVEVLGDQGLASF
                     SVGLAGVAAWTLTEYVLHRWMLHGVEPFRSWHRVHHHNAALPIRVPVLFSLLLAATVI
                     GLPALISGGSAFAAPLSAGMLLGNLLQESVHHRLHDTQPLGDWLEAKRRLHGFHHFRD
                     ERRGYGTLTDFWDRIFGTLPPRA"
     gene            complement(9114..9299)
                     /locus_tag="P5537_12700"
     CDS             complement(9114..9299)
                     /locus_tag="P5537_12700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004312935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78942.1"
                     /translation="MEPVSGCSYVIRLCSGELRRWRFEGVDVRGFGWWLDEETGFGFS
                     DASLMYAWEIVERADDG"
     gene            9904..10416
                     /locus_tag="P5537_12705"
     CDS             9904..10416
                     /locus_tag="P5537_12705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system Fe-S cluster assembly regulator"
                     /protein_id="HRV78943.1"
                     /translation="MLRISKLTDYGTLILTHMAGHPDRVHSATGLAEALGLGLPTVSK
                     VLKTLGRHELVTSQRGAHGGYTLARPPNRITVADVIDALEEQAFGLTECSSNSGVCAI
                     ESDCRIRENWMRINTVVRQALQAVNIADMVHPGPGAAFPPPHTTEHRIHGPARSAACL
                     PTARAEEQEI"
     gene            10419..11900
                     /gene="sufB"
                     /locus_tag="P5537_12710"
     CDS             10419..11900
                     /gene="sufB"
                     /locus_tag="P5537_12710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HRV78944.1"
                     /translation="MNAPTPAAATSPARRGDAIGAFLEQDYAAGFETTLDTDTVPKGL
                     SEDIIRLISARKGEPDWLLDWRLEAYRHWLTMTPPVWAAVQFPPVDFQDIVYYSAPKS
                     KKDGPKSLDEVDPELLRTFEKLGVPLHERARLAGVAVDAVFDSVSVATTFKKELGEHG
                     VIFCSFSEAVKEHPELVRQYLGTVVPPGDNFYAALNSAVFSDGSFVFIPKGVKCPMEL
                     STYFRINARDTGQFERTLIIAEEGASVSYLEGCTAPMRDENQLHAAVVELIALDDAKI
                     KYSTVQNWYPGDKDGKGGIYNFVTKRGDCRGARSHISWTQVETGSAITWKYPSVILRG
                     DDSVGDFHSVALTNNLQQADTGTKMIHMGRNTRSTILSKGISAGRGSNTFRGLVKVTP
                     KAEGARNYTQCDSLLIGDRCAAHTFPTIEVRHPTAHVEHEATTSRIGEDQLFYAMQRG
                     ISAEDAVSMIVNGFCREVFKELPMEFAVEAQKLLGVSLEGSVG"
     gene            11921..>12077
                     /locus_tag="P5537_12715"
     CDS             11921..>12077
                     /locus_tag="P5537_12715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HRV78945.1"
                     /translation="MLKINNLHAAIDGKDILKGLDLEVADGEVHAIMGPNGSGKSTLA
                     QVLAGRET"
BASE COUNT         1911 a         4351 c         4045 g         1670 t
ORIGIN      
        1 gcggccagct cgcgcgcggc ctcctcggcg aggcgggtgc gggtgagcag cgcgtcgcgc
       61 accgcctcct cccagttggg atgggcgctc agcacgatgg ggagcttgat catctcctcg
      121 gctttgagct cctcggccga gacgtggtag agcacgttgc tgcggtggcg gccctggcgc
      181 agcggggtgg cggtcatctc gatcagcgcc gccgggcgca ggggggcgaa gctgtcgtag
      241 ctcagcggcg tgcgcgcgtt gtgcgcctcg tcgataatca ccaccgggcg gtgccagtac
      301 atcaggttgg cgaagctgcg cttgaccttg ccgaggtcgg cgcggccgag gtagggctgg
      361 acctcgaggt cgcgctcgct cacgcgctcg aaaccgggca gctcgggggc gcgctcgaaa
      421 tgcggctcga agtcctcctt gtaggcatag acgtcgcgcc ccgaggtgtc gtccacgcgc
      481 agcgtctgca gcgtgccgac gatcaccagc gcacgcgcgc cgatgtcctg cgggcggatc
      541 tggtcgctgt cggcgatgtc gagcacgcgc acaccatcga cgccgaaatg cgcctccagc
      601 gcctcgcggt aggggtggcc gggggtcttc agcgcgctga gcgtctgctg gcggatcacg
      661 ttggtgggca ccagccacag cgccagcggc cggtcctggc cggtgtagtg gcgggccgcg
      721 gcggcgagcg cgtgcgcgcc gagcagggtc ttgccgccgc cggtggggat gcgcacgcac
      781 acgtagggcg tggccccatc gtcgttgacg aagccctgcg ccagataggg cgggatcgtc
      841 tccgccgcgt gctcctgttc gagcagggtc tggcggaagg cggcgtcgag cgcggcctcg
      901 tcgcgcgcgc cgcgcgccag ggcaaagaag cgcgcgagcg cggcgagcgc ctcgcgctgg
      961 taacgcttga gggtcagcgc catgccggag cctcctgtcg cgcgcggatg tcgtagggaa
     1021 tctggcggaa gtcgatgccg agcgcgcgcc ggcgcatctc ggacagccgg caggcctcac
     1081 cgaacaccac ccgcggcgtg ccagccgcca ccccggcgcc tgcggccgcc tcgtcgagca
     1141 gcgccgccac cgccgaggtc agcacgttgc cgccctgcgg ccggcggtcg ccgagcacgc
     1201 cattgaagag caggaagtag gcgcgcccct cgtgcacgcc gagcagcggc gaggccggct
     1261 gcgcgtcggc ggcctggggc cgccacgggg tgcgcgtctc ctgataccag atccacgccg
     1321 ccagcgtggc gaagccgata gcggggtcga cctggccgtc gggcaggaac accggcgcgc
     1381 cgaggcgggc gaagcgcacc ccgccgccgc cctgccagtc caccgccttc gagatcccgc
     1441 cctgttcgcc cgcgatcacc ttctgcaggc gcggcaggca gtgggtgtgc gcgtgctcgc
     1501 ccatctcgat gccgatgtag cgccgaccca tcttgtgcgc gaccgccgcg gtggtgccgg
     1561 agccgaggaa gctgtcgagn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnng
     1681 cgatgaaatt cccccgcccg aacacctcgt ccatcaacac cttcaggtag tgcccctcgt
     1741 tgtcgtcgat cgacacccag atgctgccgt cctcggcgag cagctcgcgt agcagctcca
     1801 gccgcggcgc catcatcgac agccactggc tgtgctcgag gttgtcgtcg tagtgctcga
     1861 aggcggagcg ggtgttgtag ggcgggtcga tgtagatgca cttgacccgg ccggcatgga
     1921 agggcagcag cgccttgagc gcgtcgaggt tgtcgccctg gatcagccag ttgtcggccg
     1981 cggggtcgcc gtggacggcg tccacttcga tcagccggta aggcacggcc gcggcggcct
     2041 gcagggcctg gcgcttgttc agccagtcga ggatgggcat gggtgggagc cgttcgaatc
     2101 gatgttgatg tcattgtagc cgcgaccggc ggccgagcgc gggaacagca ggtccgctgc
     2161 ggcctgcgcg cggggcccga ggataacgca tcggccgccc gggccggcag ccttgcggtg
     2221 tgtgcgaacg gttgcggccg atggtcgcgg cggaatcacc ccgccaccgc ccgcttcagc
     2281 cgcgccaccg cgccctcgac cgcgccctcg tccaggttcc cgtagccgag caccagcccg
     2341 ttgcagccca ccggcgggcg ggcgtaagcc gacagggcgc gcacgcccag cccgagccgc
     2401 gcggcgcgct gcgccaccgc gacatcgggg agcgcatcgg gcagccacat caccagatgc
     2461 agcccggcct cgccgcccga cagcaccagc ccggggccga aggcctgctg cagggcggcg
     2521 cgcagcgcgg cctggcgggc gttgtagcgg gcgcgcatgc ggcggacgtg ggtggtgtag
     2581 tggccgcgcg cgatgaagtc ggcgagcgcg cgctgctcga tgccctgccc ggcgcgggtg
     2641 gcgcgcgccg cggcgtggat gaagtcgtcc gcgaccgtgc gcggcagcac caggtagccc
     2701 aggcgcaggc ccggatacag cgtcttgctg aaggtgccgg catagaccac cggggcgtcg
     2761 gcgtgcaggc cgaacagcgc gggcggcgcc gggccggcgc ggcggaactc gctgtcgtag
     2821 tcgtcctcca cgatccaggc gccggccgcg cgggcgcgct cgatgagcgc gagccggcgc
     2881 gccagcgaca tcacccgccc ggtggggtac tggtgcgagg gggtgaccat gatcaggcgc
     2941 ggtcgccgat gctgccaatc gtcggcgccg ggggccaggc cctcggcgtc gaccgcgacg
     3001 tcgtgcaccc gcaggccggc gaggccgaag gcgacgcggg cggcgaggta gcccgggttc
     3061 tcgacccaca ccgtgtcgcc gtgatcggcg agcaggcgcg cgcacaggtc gagcgccgcc
     3121 tgcgtgccgc tggtgatcag gatctgcgcg gcgtccaccg cgaggccacg cacgctcgtc
     3181 aggtgggccg cgagcgccgc gcgcaaggcg ggatcgccac cgtgcgccgc ataaccgagc
     3241 tgccgccagc cggcgtcgcg ccacgcacgc tcgaggcagg cgcgccaggc gcgaaaggga
     3301 aaggcgccga aatccggcac gccgggcgag aacggcagcg cctcggcgtc gcgcgccggc
     3361 tcgcgctgca gcgccgccgc ggcacgcgcg gacagggtcg gcgaggcctc cggtgctggc
     3421 gacgcgggct gcgcggcgca cgccgcggcg ggcagcggcg ccacgcgcgt cccctggcgg
     3481 tccgcgacca ggcagccctc ggcgacgagc tgctcgtagg cgaacagcac cgtgttgcgc
     3541 gcgatgccga gcgtcgccgc gaggctgcgg ctggcgggca ggcacgtatt ggccggcaac
     3601 cgaccgctca ggatggcctc gcgcaggcgc aggtagagca cgcgctggcg cggcacggcc
     3661 gcgggcaggg gcggagcgag cagccagtcg agctccatcg tggctccatt cgtgtgggtt
     3721 gctgtggcac tacgcaaggt accaccacga acctaggatg gcgtggtcga aaccttcgga
     3781 gccttgaagc catgccccac accaccgccc cctccccgcg cacccgcgtc cgccgcctgc
     3841 ccgagcgcgc gcactacgac gccgacagca tcgccgccat cgtcgacgcg gcgatgctgt
     3901 gcaccgtcgc cttccagatc gacggcatgg tgcacgcgat cccgacgatc cactggcgcg
     3961 agggcgggca tctgtacatc cacggcgcca agggctcgcg catgctgaag gcgctgacgg
     4021 acggcgaagc ctgcgtgacg atcgcgctcg ccgacggcct ggtgctggcg cgctcggcct
     4081 tgcatcactc gatgaactac cgctcggtgg tgatctatgg ccgcttcgag gcggtgaccg
     4141 agcccgcgta caagctcgcc agcctgcgcg ccttcatcga cgggctctac cccgggcgct
     4201 gggacacgct gcgcccgatc aacgacaagg agctcaacgc caccaccgtg ctgcggatcg
     4261 cactcgacga ggcctcggcc aaggtgcgcg actggggcgt gaaggacgac gaggaagacc
     4321 tggagtggcc ggtgtgggcg ggcgtgatcc cgctgcgcac ggagacgggc gcgccggaga
     4381 tcgagcacga cagcgtgggc cgggtggtgc cgccgacccg cttcggataa ggggagcggc
     4441 cggcgccgca aagttcgcgc taggccatca cggacgccgc cgggtgttgc cgaagcgacc
     4501 gccgccgggg cggccaccgt acggacgcct gcgctcgtcc tcatcgtcgc gcttgggctt
     4561 gggcatcagc aggttcttgc cgccctgctg ggccagcctg gcatgatccc gcagtgccgc
     4621 ctcgaactgc tccgccccga tcccgattcc ggcgtgctcg ccgaccggct tgtacgccgc
     4681 caggcgctcg cgcaccagga acacgcgctc gtcggcctcg gccttcttcg gcaggccctc
     4741 gaccagctgc acggcggccg gcgtcagcgc gtagccctcg cgcaccgcgg tcaacagccc
     4801 gtgggtgacg aagcgctcga aggccgtggc ccacgccgcg ggcgcggtga ccggaaagcc
     4861 catgaactcg gcggccgcga cgatatcggt cagcgcggcg ggtcgcctct tcgcggcgat
     4921 cagggtcgcc agcagcaact gcgcgtcggt gccgtggatg ggatacatgg ggttcgcctg
     4981 cctctcgggt tgtgaagcgc gccatgatgc ccgaggcgcg gcgatccggc gcgggggaag
     5041 cgatcgttcc gcgcaacaaa cgtccgctcg gcttgcgtcg cgagcggaca ggctcggctc
     5101 cttaccgatc gggagcgccg gcttgcgggc ctcgccgcca ccgatccagc gaccgggctg
     5161 cccgtatcca gcccgcgctg gctatactcc ccgccacatt cacccaaggg gagacctgac
     5221 ccatgaagct cgagaccatc gccgtgcacg gcggctattc gcccgacccc accaccaagg
     5281 ccgtcgcggt gccgatctac cagaccacct cgtacgcctt cgacgacacc cagcacggcg
     5341 cggacctctt cgacctcaag gtgcagggca acatctacac ccgcatcatg aatccgacca
     5401 ccgcggtgct ggagcagcgc gtggcggagc tcgaaggcgg catcggcgcg ctcgccgtgg
     5461 cctcgggcat gtcggcgatc acctacgcca tccagaccat cgccgaggcc ggcgacaaca
     5521 tcgtctcggc ctcgacccta tacggcggca cctacaacct cttcgcccac accttcccgc
     5581 agttcggcat cgaggtgcgc ttcgccgact accgcgaccc ggacagcttc gccgcgctca
     5641 tcgacgcgcg caccaaggcg atctactgcg aatcggtggg caacccgctg ggcaacgtca
     5701 ccgacatcgg gcgcctggcc gagatcgccc acaaggccgg cgtgccgctg atcgtggaca
     5761 acaccgtgcc ctcgccctac ctgtgccgcc ccttcgagca cggcgccgac atcgtggtgc
     5821 acgcgctcac caagtacctc ggcggccacg gcaactcgat cggcggcgcc atcgtcgatt
     5881 cgggcaagtt cccctgggcc gagcacaagg cgcgcttcaa gcgcctgaac gagccggacg
     5941 tctcctacca cggcgtgtgc tacaccgagg ccctgggtgc cgccgccttc atcggccgcg
     6001 cgcgcgtggt gccgctgcgc aacaccggcg cggcgatctc gcccttcaac agcttcctga
     6061 tcctgcaagg catcgagacc ctggcgctgc gcatggaccg catctgcacc aacacgatca
     6121 aggtcgccga gtacctgaag aagcacgcca aggtcgagtg ggtgaactac gccggcctgc
     6181 ccgaccacgc cgaccacggc ctggtgaaga agtacatggg cgggcgcgcc tcgggcattt
     6241 tgtcgttcgg cgtcaagggt gggttcgagg cgggcggccg cttccaggac gcgttgaagc
     6301 tgatcacccg cctggtcaac atcggcgacg ccaagtcgtt ggcctgccac ccggcttcca
     6361 ccacccaccg ccagctctcg ccggcggaac tcgccaaggc cggcgtgtcg cccgacatgg
     6421 tgcggctgtc gatcggcatc gagcacatcg acgacatcat cgccgacctg gagcaggcgc
     6481 tggcggcggt ttgatgaggt agttggcgca cctgaacggg gcagactgcg gccgcgcagc
     6541 ggaatcgtgg tctgtcccgt atctttcgaa tcacagtctg tcccgtgttt ttcgcccccg
     6601 ctcctacagc cccccgaccc gcgtcgtttc tcctgtagga gcgccggcag gcgcgaaagc
     6661 ggcggtggag accggcacgc gcgccgagca tccgctcgcc cagttcgcgg ctgccgccgc
     6721 tcctacagaa gcccctgtcg taaggatttt cgatgctcgc agtcctgcaa cgcgtctccg
     6781 aagcgcgcgt gatcgtcgac ggcgaaacca tcggcgagat cggccccggc ctgctcgcgc
     6841 tggtgtgcgc cgagcgcggc gacacccccg ccgaggccga caagctgctc gccaagatgc
     6901 tcaagctgcg catcttttcc gacgaggccg ggaagatgaa ccgctcggtg caggacgtgg
     6961 aaggcgggtt gctggtggtc agccagttca cgctggccgc cgactcctcg ggcggcaacc
     7021 ggccgagctt caccaacgcc gccgacccgc ggaccggcca ggcgctctac gagcatttcg
     7081 tcgcgcgggc gcgcgccgcc cacccgcagg tgcagaccgg ccgcttcgcc gccgacatga
     7141 aggtgcaact catcaacgat ggcccggtca cagtgccgct gcgcatcgcc ccgaccggaa
     7201 ccgacaacgc ccggggtttg ctgtaggagc gccggccggc gcgaatgccg cgctcgggga
     7261 atcgatgcac cggcaatcga acgaccgccg ccttcgcgcc tgccggcgct cctacatgac
     7321 gcacccgagc gcggggtgac tgatccacgg cgcggcgggg cataatcgtc cctcccaacc
     7381 cctagcccca ggagacaaca tgaagctcta cctcaaaccc ggcgcctgct cgctctcgcc
     7441 ccacatcgcg ctggaggaat ccggcctgcc ctacgagacc gaggcggtcg acctcaagac
     7501 caaggtgacc gccagtggcg cagacttctg gaagagcaac cccaagggct acgtgccggc
     7561 gctgctgctc gacagcggcg agttgctcac cgaaggcgcg gcgatcgtgc agtacatcgc
     7621 cgatcaggcg ccgggcaaga agctcgcccc cgccaacggc agcatcgagc gctatcgcct
     7681 gcagtcctgg ctcaacttca tcggatcgga actgcacaag tcctgcagcc ccttcttcaa
     7741 cccggcctcg ggcaaggagt ggaaggagat cgcgggcgcc aacctcgagc gtcgcctcgg
     7801 ttatgtgaac gaggcactcg aaggcaagcc ctacctgatg ggcgaggact tcagcgtcgc
     7861 cgacggctac ctcttcaccg tgctgagctg gatgaagttc gtcggcatcg acctggcgaa
     7921 gtggcccaac ctgacggcct tccagacccg cgtggccgcg cgcccggcgg tgcaggcggt
     7981 gttgaaggct gaggggttgg cgtgagggaa gtccggcgtt aggcgtcagc cgtcgccggc
     8041 ggctcggcca ttcgcggcgg ccgccgctcc tacaggaaac cgtcgtgctc cgcggccttg
     8101 caggagcggc ggcagccgcg agcctttcac gcacggctcc atgaccgcaa cgactgcagc
     8161 cgactcgcac gccatctctc catgaccgat ccatcctctc gcctccccct cctcgccggc
     8221 gcgctgctcg ccgcgctcgg cgtcgcgctc ggggccttcg gcgcgcatgc gctgcgcggc
     8281 gcgctcgacg ccaccgccca gggctggtgg cagaccgccg tgcagtacca gatgtggcac
     8341 gccctcggcc tgctcgcgat cggcgctgcg cgcgtgccgg gaagccgcct tgcggccctg
     8401 ctcctcgccg ccggcaccct ggtcttctgt gccacgctct acctgatggc gctcggcgcg
     8461 ccccgctggc tgggcgccat caccccgatc ggcggcagcc tgatgatcgc cggctggctg
     8521 gtgctggcct ggcgggtggc gcgcctgcgc gcttgaggcc gcagcgcgtt caggcgcgcg
     8581 gcggcagcgt gccgaagatg cggtcccaga aatccgtcag cgtgccgtag cctcggcgct
     8641 cgtcgcggaa atgatggaag ccgtgcagac gccgcttcgc ctccagccag tcgccaagcg
     8701 gttgggtgtc gtgcaggcgg tggtgcaccg actcctgcag gaggttgccg agcaacatgc
     8761 ccgccgacaa gggcgcggcg aacgcactcc cgcccgagat cagcgcaggc aggccgatca
     8821 ccgtcgccgc aagcagcagg ctgaacagca ccggcacgcg gatcggcagc gccgcattgt
     8881 gatgatggac acgatgccaa gaccggaacg gctccacccc gtgcagcatc cagcggtgga
     8941 ggacgtactc ggtcagcgtc cacgccgcca cgccggcaag gccgactgaa aaagaggcga
     9001 ggccctgatc cccaagcacc tccaccggcc agttcatcgc cagcaccacc aggccggcgc
     9061 aaggcaccgc cagcgaggcc ggataggcga gcgcgacgcg cagcatccag ggctcagcca
     9121 tcgtcggcgc gctccacgat ctcccaggcg tacatcaggc tcgcatcgga gaagccgaac
     9181 ccggtctcct cgtccagcca ccagccgaat ccgcgcacat ccacgccctc gaagcgccac
     9241 ctccgcagct cgccgctgca caggcggatg acatagctgc agccgctgac gggttccatg
     9301 tcgttcaaat cctctagatc gttggcccgg cgccgatcgg acgctctgat cgaatcatag
     9361 ccgcggcgct gcgtcatggc ggcgccaatt ccaaacaccg cattcgcggc tgccgccgct
     9421 cctacagccc ccccgaaccg catcggtttt atgtaggagc gccggcaggc gcgaatgcgg
     9481 cggtacagac ccctacaccc accgagcccc cgccgccaga ttcgcggctg ccgccgctcc
     9541 tacaggcccc ccgaaccgca tcggttttat gtgggagcgc cggcaggagc gaatgcggcg
     9601 gtacagaccc ctacacccac cgagcccacg ccgccagatt cgcggctgcc gccgctccta
     9661 cagccccccg aaccgcatcg gttttatgta ggagcgccgg caggcgcgaa tgcagcggta
     9721 cagaccccga cacccaccga gcccacgccg ccagattcgc ggctgccggc gctcctacag
     9781 cccacccgaa gcacgtcggt ttcatgcagg cgctgccgga aagtcgcaga tgctccgcgg
     9841 cttgactata cagtaccgtt ttggtacttt taatcccgaa cccacccccg cgagcacatt
     9901 gccatgctgc gcatcagcaa actcaccgac tacggcaccc tgatcctgac ccacatggcc
     9961 gggcatcccg atcgcgtgca cagcgcgacc ggccttgccg aggcgctcgg cctgggcctg
    10021 cccacggtca gcaaggtgct caagaccctc ggccgccacg agctggtgac cagccagcgc
    10081 ggtgcgcatg gcggctacac gctcgcccgc ccgccgaacc gcatcaccgt ggcggacgta
    10141 atcgacgccc tcgaggagca ggccttcggg ctcaccgagt gcagctcgaa cagcggcgtg
    10201 tgtgcgatcg aatccgactg ccgcatccgc gagaactgga tgcggatcaa caccgtggtg
    10261 cgccaggcac tgcaggcggt caacatcgcc gacatggtcc accccggccc cggcgccgcc
    10321 tttccgcccc cgcacaccac cgaacaccgc atccacggcc ccgcgcgcag cgccgcctgc
    10381 ctcccgaccg cgcgtgcaga agaacaggag atctgaagat gaacgccccc accccggcag
    10441 ccgccacctc ccccgcccgc cgcggcgacg ccatcggcgc cttcctcgag caggactacg
    10501 ccgccggctt cgagaccacg ctcgacaccg acaccgtgcc caagggcctg tcggaagaca
    10561 tcatccgcct catctccgcg cgcaagggcg agcccgactg gctgctcgac tggcgcctgg
    10621 aggcctaccg ccactggctg acgatgacgc cgccggtctg ggccgcggtg cagttcccgc
    10681 cggtggactt ccaggacatc gtgtactact ccgcgcccaa gtcgaagaag gacggaccca
    10741 agagcctgga cgaggtcgat cccgagctgc tgcgtacctt cgagaagctc ggcgtgccgc
    10801 tgcacgagcg cgcccgcctg gccggcgtgg cggtcgatgc ggtgttcgac tcggtgagcg
    10861 tggccacgac cttcaagaag gagctcggcg agcacggcgt gatcttctgt tccttctccg
    10921 aggcggtgaa ggagcacccg gagctggtgc gccagtacct cggcaccgtg gtgccgccgg
    10981 gcgacaactt ctacgccgcg ctcaactcgg cggtgttctc cgacggctcc ttcgtcttca
    11041 tccccaaggg cgtgaagtgc ccgatggagc tgtcgaccta cttccgcatc aacgcccgcg
    11101 acaccggcca gttcgagcgc acgctgatca tcgccgagga aggcgcgtcg gtcagctacc
    11161 tcgagggctg taccgcgccg atgcgcgacg agaaccagct ccacgccgcg gtggtcgagc
    11221 tgatcgcgct cgacgacgcc aagatcaagt attccaccgt gcagaactgg tacccgggcg
    11281 acaaggacgg caagggcggc atctacaact tcgtcaccaa gcgcggtgac tgccgcggcg
    11341 cgcgctcgca catctcctgg acccaggtcg agaccggctc ggcgatcacc tggaagtatc
    11401 cgagcgtgat cctgcgcggc gacgattcgg tcggcgactt ccactcggtg gcgctgacca
    11461 acaacctgca gcaggccgac accggcacca agatgatcca catggggcgc aatacgcgca
    11521 gcaccatcct cagcaagggc atctcggccg ggcgcggcag caacaccttc cgcggcctgg
    11581 tcaaggtcac gcccaaggcc gagggcgcgc gcaactacac ccagtgcgac tcgctgctga
    11641 tcggcgaccg ctgcgccgcg cataccttcc caaccatcga ggtgcgccac cccacggccc
    11701 acgtcgagca cgaggccacc acctcgcgca tcggcgagga ccagctcttc tacgcgatgc
    11761 agcgcggcat cagcgcggaa gacgcggtgt cgatgatcgt caatggcttc tgccgcgagg
    11821 tgttcaagga actgccgatg gaattcgcgg tggaagcaca gaaattgctg ggcgtgagcc
    11881 tcgaaggcag cgtcggctaa ggacccacag gagaatcgag atgctgaaaa tcaacaacct
    11941 gcacgccgca atcgacggca aggacatcct caagggcctc gacctcgagg tcgccgacgg
    12001 cgaggtgcac gccatcatgg gtcccaacgg ctcgggcaag agcacgctcg cccaggtgct
    12061 ggccgggcgc gagacct
//
LOCUS       DAOTIN010000096        12062 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_6296_length_12062_cov_8.599150, whole genome shotgun sequence.
ACCESSION   DAOTIN010000096 DAOTIN010000000
VERSION     DAOTIN010000096.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 12062)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 12062)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12062
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6296_length_12062_cov_8.599150"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            99..944
                     /gene="hpnC"
                     /locus_tag="P5537_12720"
     CDS             99..944
                     /gene="hpnC"
                     /locus_tag="P5537_12720"
                     /EC_number="2.5.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011765616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="squalene synthase HpnC"
                     /protein_id="HRV78946.1"
                     /translation="MPVEHYENFPVASLLLPARLREPVEAIYAFARGADDVADEGDAP
                     AVARLARLHDYQLGLEACAQGRPVADATLAPMFARLGGAIRAHALPLQPFRDLLDAFM
                     QDVAKTRYADFAELRDYCRRSADPVGRLMLHLYGAATADNLRRSDAVCTSLQLINFWQ
                     DVAVDWEKRRIYLPLDELARFGLDERALDALARGERGPGEDWRALMAFEVQRARTMML
                     DGAPLARALPGRVGWELRLVVLGGLRILERIEAVGYDVFRHRPALGRGDWARLAWRAL
                     NYGKF"
     gene            944..1777
                     /gene="hpnD"
                     /locus_tag="P5537_12725"
     CDS             944..1777
                     /gene="hpnD"
                     /locus_tag="P5537_12725"
                     /EC_number="2.5.1.103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA];
                     GO_process: GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="HRV78947.1"
                     /translation="MNPHDYCQDKAAKSGSSFYYSFMFLPPERRQAITALYAFCREVD
                     DVVDECHDLSLAQTKLEWWRQEVGRVYAGTPTHPVGHALKDVIKGFRLPQEQLLEIID
                     GMAMDLSQTRYLDFKGLQLYCYRVASVVGLLAAEIFGYQDRQTLKYAHDLGLAFQLTN
                     IIRDVGEDARRGRIYLPIEDLQRFEVPAKDLLEARYSDAFRELMAFQAERAEKFYDQA
                     FAQLPAIDRKAQRPGLVMAAIYRTLLREIAADGFLVLDRRTSLTPLRKVWLAGTTWFR
                     A"
     gene            1774..3099
                     /gene="hpnE"
                     /locus_tag="P5537_12730"
     CDS             1774..3099
                     /gene="hpnE"
                     /locus_tag="P5537_12730"
                     /EC_number="1.17.8.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="HRV78948.1"
                     /translation="MSVPVVAIIGAGYAGLACAVELARAGVHVTVFERSHTMGGRARV
                     VHKDHHWRVDNGQHILIGAYSELTRLLRLTGVSPKQLAHLPLTLHVPGRLHLKAASLP
                     APFHLAVGLLRSKGLSWADRLAMLRLMRWLKRHGFRLPDAAMTVDALLAETRQTATLC
                     QLIWEPLCVAALNTPVAEASAQVFANVLRDSLAAGAAASELLLPRTDLSELFPVPAAR
                     YIGVRRGKLRTGNAIEAIERVPGGYRLEGDPGSQPWPHVVVATAPYHAGTLLASAGGC
                     ERLVAQIDALEHEPIVSVYLALGRGQKLPEPMIGLVSGSTAGPAQWVFDRGQLGGPEG
                     LLSCVISAHGPHEALARDELVLAVHAQLERQLGRRLPAPEWSQVIVEKRATFACRPGI
                     FRPGIRTPLPGLWLAGDYLDSDYPATLESAVRSGVACATAILAEIGHKA"
     gene            complement(3178..4314)
                     /locus_tag="P5537_12735"
     CDS             complement(3178..4314)
                     /locus_tag="P5537_12735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M14-type cytosolic carboxypeptidase"
                     /protein_id="HRV78949.1"
                     /translation="MKISSTFDSGAIEVVRLDDPADIRLRLRKDNAADFHQWFHFRLM
                     GAAGKPVRMVFENAASAAYPDGWKDYRCVASYDRQNWFRIAGTRYEDGQLVVEHTPER
                     DSLYYAYFEPYSHERHLDLLARVELSPYARVRNLGSSVDGRDIDLVTVGREAPGRVPV
                     WIIARQHPGETMAEWFVEGLLERVLDNADPVARKVREHAVLHIVPNMNPDGAVRGNLR
                     TNAAGRNLNREWREPDPAASPEVFLVRAEMERSGCALFLDIHGDESLPYVFFSTAEEV
                     PGFTAAAAAAQARFVDTFLAVSPDFQTQEGYKPGRFGEELLTLASKWVANHFGCVSLT
                     LEMPFKDNAILPDGHVGWNGARSKRLGAAMLDPILRHLREGGEG"
     gene            complement(4320..5105)
                     /gene="yaaA"
                     /locus_tag="P5537_12740"
     CDS             complement(4320..5105)
                     /gene="yaaA"
                     /locus_tag="P5537_12740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HRV78950.1"
                     /translation="MILVISPAKALDYETPVSVSTHTQPDFLDDSAALIEVLREKSPA
                     EIAALMALSDPLSTLNVARYASWSRPFGPDNARQALLAFNGDVYEGLDARSLSADELA
                     WAQDHLRILSGLYGVLRPLDLMQAYRLEMGTRLANPRGKNLYEFWGERITDELNRLLA
                     REEEAGRERVLLNLASDEYFKSVKPKKLKGRIVTPVFEDWKGGRYKIISFYAKRARGL
                     MSRYVIGKRIDEVEALQGFDAEGYAFAADASDADTLIFRRREE"
     gene            complement(5178..5684)
                     /locus_tag="P5537_12745"
     CDS             complement(5178..5684)
                     /locus_tag="P5537_12745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78951.1"
                     /translation="METYAKTPKGQDEIAHRTHGLGLRARRLLILVDGQRSVEDLRGL
                     TGDAGTADALGELAAEGFIAPRGDASRPGEAGGRETHTSPAPVARANTGHAASLPLAR
                     DFMINTLRTFHGPYAKLDLVKRIHATQSGGELRRLIMEWQQSIAESRLGRKRADELLA
                     RLEEVMPG"
     gene            complement(5925..6737)
                     /locus_tag="P5537_12750"
     CDS             complement(5925..6737)
                     /locus_tag="P5537_12750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HRV78952.1"
                     /translation="MTEPQLKPLASRDNPFVKRLHALAHSARERRKLDETVLDGAHLV
                     EAALAAGVPLRALVVSETGLLREEHRRLLAAAPAEVPRYRLGDALFAHLSPVESPAGL
                     LATIAMPASAPGDLGEASLIVLDGVQDPGNLGSLLRTAAAAGIRNALLGEGCAQAWSP
                     RALRAGMGAQFVVRIEEGCDLLARLEPYRGRCLATALRDDARPLYELDLRGPVAWLFG
                     AEGQGLSSGLLARADRCVIIPMAAGIESLNVAAAAAVCLFEQARQRRTTTKP"
     gene            complement(6730..7341)
                     /gene="rnhB"
                     /locus_tag="P5537_12755"
     CDS             complement(6730..7341)
                     /gene="rnhB"
                     /locus_tag="P5537_12755"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HRV78953.1"
                     /translation="MTGDLFAPALPASGLVCGVDEAGRGPLCGPVVAAAVILDPARPI
                     DGLADSKKLSEAARERLAPLIRERALAWAVAEASVEEIDRLNILHATMLAMQRAVMAL
                     GTAPAEVRIDGNRCPTLPYPARAIVKGDATEPSISAASILAKTARDAAMRELDARWPQ
                     YGLAVHKGYPTAAHLAALAEHGVQAFHRRSFAPVKKLLERRDD"
     gene            complement(7338..8495)
                     /gene="lpxB"
                     /locus_tag="P5537_12760"
     CDS             complement(7338..8495)
                     /gene="lpxB"
                     /locus_tag="P5537_12760"
                     /EC_number="2.4.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008915 - lipid-A-disaccharide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-A-disaccharide synthase"
                     /protein_id="HRV78954.1"
                     /translation="MKVRIAMVAGETSGDLLASHLIRALRRHLPDAEFFGIGGPKMQA
                     EGFEVRWPCELLAVHGYVDALKRYRELSGIRRDLLGQIRAERPDAFIGVDAPDFNLWL
                     EGKVRDAGIPAIHFVGPSIWAWRGGRIKRIARSVSHMLCLFPFEPELYERAGVPVSYV
                     GHPLADEFPLEPDRAEARERLGIAAERRVVAMLPGSRQSEVRNLADIFIGTAKILHER
                     DPERLFLVPLATRETRQLFEEALHRQDAGELPIRMLFGHAVEAMTAADVVLVASGTAS
                     LEAALLKRPMVITYRIGKWQYRLMKRMAYLPWVGLPNILCGETVVPELLQDEADPEHL
                     AAAIDDWFADDARRAAVEARFTALHHTLRQDTARRAAEAILSYLDKARAAG"
     gene            complement(8524..9294)
                     /gene="lpxA"
                     /locus_tag="P5537_12765"
     CDS             complement(8524..9294)
                     /gene="lpxA"
                     /locus_tag="P5537_12765"
                     /EC_number="2.3.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008780 -
                     acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine
                     O-acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP--UDP-N-acetylglucosamine
                     O-acyltransferase"
                     /protein_id="HRV78955.1"
                     /translation="MIHPTAIVHPGAKLGANVSVGAYSLIGEHVEIGDGTRIGPHVVV
                     EGHTRIGRDNEIFQFCSIGASPQDKKYDAEPTRLEIGDRNTIREFCSFNVGTSQDAHV
                     TRVGNDNWIMAYVHIAHDCQVGDHTIFANNATLAGHVHVGDWAILGGFTGVHQFCRVG
                     AHSFCGVGTVLLQDLPPFVTVAGNPAKPHGINSEGLKRRGYSTEGIAAIKRAYRALYR
                     AGLSLDEARQRVAEIAAEQAEVAAFAEFIADSGRGIVR"
     gene            complement(9291..9725)
                     /gene="fabZ"
                     /locus_tag="P5537_12770"
     CDS             complement(9291..9725)
                     /gene="fabZ"
                     /locus_tag="P5537_12770"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HRV78956.1"
                     /translation="MDIKEILQYLPHRYPFLLVDRMLEIEPGVRARGLKNVTMNEPFF
                     PGHFPHHPVMPGVLIIEAMAQAAALLSFKSTGVKPDDNSVVYFAGIDNARFKRPVVPG
                     DQLIFDVEITHAKRNIYKYKARASVDGELAAEADLMCAIKTL"
     gene            complement(9732..10766)
                     /gene="lpxD"
                     /locus_tag="P5537_12775"
     CDS             complement(9732..10766)
                     /gene="lpxD"
                     /locus_tag="P5537_12775"
                     /EC_number="2.3.1.191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016410 - N-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-(3-hydroxymyristoyl)glucosamine
                     N-acyltransferase"
                     /protein_id="HRV78957.1"
                     /translation="MFRLQELVDRLGGEIAGDGSVAVGRVAPLDTARDGDLAFLANRK
                     YLSQVGECAASALIVTPDLREALAGRNLILSADPYLYFARVAQLFNPPPAVRPGIHPT
                     AAVASTLPSSVQVGSGASIEEDVVVGEDVVIGPNCHVGRGTRIGRGTRLYANVTVYHD
                     CLIGEDCILHSGVVIGADGFGFAREKSGAWVKIPQTGRVVLGNDVEIGANTTVDRGAL
                     DDTVIGDGVKLDNLIQIAHNVHVGEHTIMAGCAGVAGSARIGARCMIGGQAGISGHLS
                     IADDVVVSAWTLVAKSITKPGVYTSNLPLQTHGDWVKNFSHLRHLDALARRVRQLEQH
                     SDGPDDRSQG"
     gene            complement(10780..11280)
                     /locus_tag="P5537_12780"
     CDS             complement(10780..11280)
                     /locus_tag="P5537_12780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpH family outer membrane protein"
                     /protein_id="HRV78958.1"
                     /translation="MKVRTLSLVAVALLGLSHTAFAETKIGFVNSDRVMREAAPAVRA
                     QQRLEKEFEKRDQELQRIARDLKSMQEDLERNGPTMGDSDRRNKERSFNELNRDFQRK
                     QREFREDLNQRRNEELASVLDKANRSVKEIAEQENYDIIFQEAVYANPRIDITDKVIK
                     TLSDAK"
     gene            complement(11315..>12062)
                     /locus_tag="P5537_12785"
     CDS             complement(11315..>12062)
                     /locus_tag="P5537_12785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="BamA/TamA family outer membrane protein"
                     /protein_id="HRV78959.1"
                     /translation="EITTYNLSPLLYKDFCRENGLDNVSGVGECTVDSLVLTVGWSRD
                     GRDSFVYPRSGVYQRLYGEVTVPVGDLRYGKLGYQYQHWFPIGSDYALMLNADVGYAK
                     GFGGKEVPFYKNYYVGGIGSVRGFDQGSVGPKYQDTDGDITSTGGTRKVVGNAEFFFP
                     MPGAGKDRSFRISAFFDAGYVWGEDEVPLGGGSFVEQDVRFGDLRYSTGLAFSWSSPI
                     GPLKFSFGHPLKKEENDEVQRFQFQLGSVF"
BASE COUNT         1741 a         4134 c         4293 g         1894 t
ORIGIN      
        1 cgatcgcccc agcgcccgat tcgcgcctgc cggcgctcct gcaggtgggt gcggatatac
       61 tgcggcacct tgcggatcct gccgcttcct tgtccccgat gcccgtcgag cactacgaga
      121 acttccctgt cgcctccctg ctgttgccgg cgcgcctgcg cgaaccggtg gaggcgatct
      181 atgcgttcgc gcgcggggcc gacgacgtcg ccgacgaggg cgatgcgccc gcggtggcgc
      241 ggctggcgcg gctgcacgac taccagctcg ggctggaggc ctgcgcgcag ggccggccgg
      301 tggccgacgc gacgctggcg ccgatgttcg cccgcctcgg tggcgcaatc cgggcgcacg
      361 ccctgccgct gcagcctttt cgcgacctgc tcgacgcctt catgcaggac gtggccaaga
      421 cgcgttacgc cgatttcgcc gaactgcgcg actactgccg gcgctcggcc gacccggtgg
      481 gccgcctgat gctgcatctc tacggcgccg cgaccgccga caacctgcgc cgctcggacg
      541 cggtctgcac gagcctgcag ctgatcaact tctggcagga cgtcgcggtc gactgggaga
      601 agcggcgcat ctacctgccg ctcgacgagc tcgcccgctt cggcctcgac gagcgcgcgc
      661 tcgacgcgct ggcccgcggc gaacgcggcc cgggcgagga ctggcgcgcg ctgatggcct
      721 tcgaggtgca acgcgcacgc accatgatgc tcgacggcgc cccgctcgcc cgcgccctgc
      781 ccggccgcgt cggctgggag ctgcgcctcg tggtgctggg cgggctgcgc atcctcgaac
      841 gcatcgaggc ggtgggctac gatgtctttc gccaccgccc cgcgctcggc cgcggcgact
      901 gggcgcgcct cgcctggcgc gcgctgaact acggaaaatt ctgatgaacc ctcacgacta
      961 ctgccaggac aaggccgcca agagcggctc gagcttctac tacagcttca tgttcctgcc
     1021 ccccgagcgc cgtcaggcga tcaccgcgct gtacgccttc tgccgcgagg tggacgacgt
     1081 ggtggacgag tgccacgacc tctcgctcgc gcagaccaag ctcgagtggt ggcggcagga
     1141 ggtcgggcgc gtctacgccg gcacgcccac gcacccggtt ggccacgcac tcaaggacgt
     1201 gatcaagggc tttcgcctgc cgcaggagca gttgctcgag atcatcgacg gcatggcgat
     1261 ggacctgtcg cagacacgct acctcgactt caagggcctg cagctctact gctaccgcgt
     1321 cgccagcgtg gtcggcctgc tcgccgcgga gatcttcggc taccaggacc gccagacgct
     1381 caagtacgcg cacgacctcg ggctggcctt ccagctcacc aacatcatcc gcgacgtcgg
     1441 cgaggacgcc cgccgcggcc gcatctacct gccgatcgag gacctgcagc gcttcgaggt
     1501 gcccgccaag gacctcctcg aggcgcggta ttccgacgcc ttccgcgagc tgatggcctt
     1561 ccaggccgag cgcgccgaga agttctacga ccaggccttc gcccagttgc ccgcgatcga
     1621 ccgcaaggcg cagcgccccg gcctggtgat ggcggcgatc taccgcaccc tgctgcgcga
     1681 gatcgccgcg gacggtttcc tggtgctcga ccgccgcacc tcgctgacgc cgctgcgcaa
     1741 ggtctggctc gcgggcacga cctggttccg cgcatgagcg tgccggtcgt cgccatcatc
     1801 ggtgccggct acgccgggct cgcctgcgcg gtcgagctcg cgcgcgccgg ggtgcacgtc
     1861 accgtgttcg agcgctcgca caccatgggc ggccgtgccc gcgtggtgca caaggaccac
     1921 cactggcggg tggacaacgg ccagcacatc ctcatcggcg cctacagcga gctcacccgc
     1981 ctgctgcgcc tcaccggcgt gtcgcccaag cagctcgccc acctgccgct cactctgcac
     2041 gtgcccggcc ggctgcacct gaaggcggcg tcgctgcccg cgccctttca cctcgccgtc
     2101 ggcctgctgc gatcgaaggg tctgagctgg gccgaccgcc tggcgatgct gcggctgatg
     2161 cgctggttga agcggcacgg cttccgcctg cccgacgcgg cgatgacggt cgacgcgctg
     2221 ctcgccgaga cgcgccagac ggcaacgctg tgccagctga tctgggagcc cttgtgcgtg
     2281 gccgcgctca acaccccggt cgccgaagcc tcggcccagg tcttcgccaa cgtgctgcgc
     2341 gacagcctcg ccgcgggcgc cgccgcgagc gagctgctgc tgccgcgcac cgacctgtcc
     2401 gagctctttc cggtgcccgc cgcgcgctac atcggcgtgc gccgcggcaa gctgcgcacc
     2461 ggcaacgcga tcgaggccat cgagcgggtg cccggcggct accgcctcga gggcgacccg
     2521 ggcagccagc cctggcccca cgtggtggtg gccacggcgc cctaccacgc cggaacgctg
     2581 ctcgcctccg ccggcgggtg cgagcgcctg gtggcgcaga tcgacgcgct cgagcacgag
     2641 ccgatcgtgt ccgtctacct cgccctcggg cgcggccaga agctgcccga gccgatgatc
     2701 ggcctggtct cgggcagcac cgccgggccg gcgcagtggg tcttcgaccg cggccagctg
     2761 ggcgggccgg agggtttgct ctcttgtgtg atcagcgccc acggaccgca cgaggcgctg
     2821 gcccgcgacg agctcgtgct cgcggtgcac gcccagctcg aacgccagct cggacgccgc
     2881 ctgccggcgc ccgagtggtc gcaggtcatc gtcgagaagc gcgccacctt cgcgtgccgg
     2941 ccgggcatct tccgccccgg catccgcacc ccgctgccgg ggctgtggct ggccggcgac
     3001 tatctggatt cggactaccc cgcgacgctg gagtcggcgg tgcgctcggg cgtggcctgc
     3061 gcgaccgcga tccttgcgga gatcggccac aaggcctgat cacggccgca gatcgaccgg
     3121 cggccttgtc gcgtcgaggt ccggccgccg cggcaaggcc ctgccgcacc ctgccgctca
     3181 gccttcgccg ccctcccgca ggtggcgcag gatcggatcg agcatcgccg cgcccaggcg
     3241 cttgctgcgc gcgccgttcc agcccacgtg gccgtcgggc aggatggcgt tgtccttgaa
     3301 gggcatctcc agcgtcagcg acacgcagcc gaagtggttg gcgacccact tgctcgccag
     3361 cgtcagcagt tcctcgccga agcggccggg cttgtagcct tcctgcgtct ggaagtcggg
     3421 gctcaccgcg aggaaggtgt cgacgaagcg cgcctgtgcg gccgctgccg cggcggtgaa
     3481 gccgggcacc tcctccgcgg tggagaagaa cacgtagggc agcgactcgt cgccgtggat
     3541 gtcgaggaag agcgcgcagc cgctgcgctc catctcggca cgtaccagga agacctcggg
     3601 gctggctgcg ggatcgggct cgcgccattc gcggttgagg ttgcgcccgg cggcgttggt
     3661 gcgcaggttg ccgcgcacgg cgccgtccgg gttcatgttg gggacgatgt gcagcaccgc
     3721 atgctcgcgc accttgcgcg cgaccgggtc ggcgttgtcg agtacgcgct cgagcaggcc
     3781 ctcgacgaac cactccgcca tggtctcgcc ggggtgctgg cgggcgatga tccacaccgg
     3841 tacgcgcccc ggggcctcgc gcccgaccgt caccaggtcg atatcgcgcc cgtcgaccga
     3901 gctgccgagg ttgcgcacgc gggcgtaggg cgagagctcg acgcgcgcga gcaggtcgag
     3961 atggcgctcg tgcgaatagg gctcgaagta agcgtagtac aggctgtcgc gctcgggcgt
     4021 gtgctcgacg acgagctggc cgtcctcgta gcgcgtgccg gcaatgcgga accagttctg
     4081 gcggtcgtag gaggcgacgc agcggtagtc cttccagccg tccggatagg ccgcgctcgc
     4141 ggcgttctcg aacaccatgc gcaccggctt gccggccgcg cccatgaggc ggaagtggaa
     4201 ccactggtgg aagtcggcgg cgttgtcctt gcgcaggcgc aggcggatgt cggccggatc
     4261 gtcgaggcgc acgacctcga tcgcgcccga gtcgaaggtg gagctgatct tcagcacgct
     4321 cactcctcgc ggcggcggaa gatcagggtg tcggcgtcgg acgcgtccgc cgcgaaggcg
     4381 tagccctcgg catcgaagcc ctgcagcgcc tcgacctcgt cgatgcgctt gccgatcacg
     4441 taacggctca tcagcccgcg cgcgcgcttg gcatagaagc tgatgatctt gtagcgccca
     4501 cccttccagt cctcgaagac cggcgtgacg atgcggccct tcagcttctt cggcttcacc
     4561 gacttgaagt actcgtcaga ggcgaggttc agcagcacgc gctcgcgccc ggcctcttcc
     4621 tcgcgcgcga gcaggcggtt gagttcgtcg gtgatgcgct cgccccagaa ctcgtacagg
     4681 ttcttgccgc gcgggttggc cagccgggtg cccatctcga ggcgataggc ctgcatcagg
     4741 tcgagcggac gcagcacacc gtagagaccg gagaggatgc gcaggtggtc ctgcgcccag
     4801 gccagctcgt ccgcagacag gcttctcgcg tccagcccct catagacatc gccattgaag
     4861 gcgagcaggg cctgacgcgc gttgtcgggg ccgaaggggc gcgaccagct ggcgtagcgc
     4921 gccacgttga gcgtggacag tggatcggag agcgccatca gcgcggcgat ctcggcgggc
     4981 gatttctcgc gcagcacctc gatcagcgcc gcggagtcgt cgaggaagtc gggctgggtg
     5041 tgtgtggaga cggaaaccgg cgtctcgtag tcgagcgcct tggcggggga gatgacgagg
     5101 atcatgcctt tgattcgctg agtcggcgcg aggccgggtg gcaggatgtt aacgcgaatc
     5161 gccccgccac aaccccttca gcccggcatg acctcctcca gacgtgcgag cagctcgtcg
     5221 gcgcgcttgc ggccgaggcg cgactcggcg atcgattgct gccactccat gatcagcctg
     5281 cgcagctcgc cgccgctctg ggtggcgtgg atgcgcttga cgaggtcgag cttggcgtag
     5341 gggccgtgga aggtgcgcag ggtgttgatc atgaagtcgc gcgcgagcgg caggctggcc
     5401 gcgtggccgg tgttcgcgcg cgcgactggc gccgggctcg tgtgcgtctc acgcccgccg
     5461 gcctcgcccg ggcgtgacgc atcgccgcga ggcgcgatga agccctcggc tgcgagctcg
     5521 ccgagcgcgt ccgcggtgcc ggcgtcgccg gtgaggccgc gcaggtcctc gacgctgcgc
     5581 tgtccatcga ccaggatcag caggcggcgc gcgcgcagcc cgagcccgtg cgtgcggtgc
     5641 gcgatctcgt cctgcccctt gggtgtcttg gcgtacgttt ccatcctgct cctctccggg
     5701 cgcggccccc cgtggtgtcg tccccagggg gccggtacgg attctgccgt ggccccgagg
     5761 aatgcgggaa gcatcggaga aatcccgcgt cggcgtcaag atgcaccggc aggcgggcag
     5821 ggggtcctgc cgacacgagc cgcaagctcc aaggcccaag ggccgattcg cggcggccgc
     5881 cgctcctaca gggaagcatc acggctcgga ggaagaccaa cgcgtcaggg cttcgtcgtg
     5941 gtgcggcgct gccgtgcctg ctcgaacagg cacaccgcgg cagccgcggc gacgttgagg
     6001 gattcgatgc cagccgccat cggaatgatc acgcagcggt cggcacgcgc gagcaggccc
     6061 gatgagagcc cctgcccttc cgccccgaac agccaggcca ccgggccgcg caggtcgagc
     6121 tcgtagagtg ggcgggcgtc gtcgcgcagg gcggtggcca ggcagcgacc gcgataaggc
     6181 tcgagccggg cgagcagatc gcacccctcc tcgatgcgaa cgacgaactg cgcgcccatg
     6241 ccggcacgca gcgcgcgcgg cgaccaggcc tgcgcgcagc cttcgccaag cagcgcgttg
     6301 cggattccgg cggcggcggc cgtacgcagc aggctaccga ggttgccggg gtcctgcacg
     6361 ccatcgagca cgatcaggct ggcctcgccg aggtcgccgg gcgcgctcgc cggcatggcg
     6421 atggtggcca gcaggcccgc ggggctttcg accgggctga gatgcgcaaa caaggcgtcc
     6481 cccagccgat agcgcggcac ctcggcaggc gccgccgcga gcaggcggcg atgctcctcg
     6541 cgcagcaggc cggtctccga caccaccagc gcgcgcagcg ggacgcctgc ggcgagcgcg
     6601 gcctcgacca ggtgcgcgcc atcgagcacg gtctcgtcga gcttgcggcg ctcgcgcgcc
     6661 gagtgggcga gcgcgtgcag gcgcttgacg aaggggttgt cgcgcgaggc cagcggcttg
     6721 agctgcggct cagtcatccc ggcgctcgag cagcttcttc accggcgcga agctgcggcg
     6781 gtggaaggcc tgcacgccgt gctccgcgag cgcggcgagg tgggccgcgg tcgggtagcc
     6841 cttgtgcacg gccagcccgt actgcggcca gcgcgcgtcg agttcgcgca tggcggcgtc
     6901 gcgggcggtc ttggcgagga tggaggcggc cgagatcgag ggctcggtgg cgtcgccctt
     6961 gacgatcgcg cgcgccggat acggcagcgt ggggcagcgg ttgccgtcga tgcgcacctc
     7021 ggcaggcgca gtgccgagcg ccatcaccgc acgctgcatg gccagcatgg tggcgtgcag
     7081 gatgttgagg cggtcgatct cctcgacgct cgcctcggca accgcccagg ccagcgcgcg
     7141 ctcgcggatc agcggcgcga gacgctcgcg tgcggcttcg ctcagcttct tggagtcggc
     7201 gaggccgtcg atcgggcgcg cgggatcgag gatcaccgcg gcggcgacca ccggcccgca
     7261 cagcggtccg cgccccgcct cgtccacccc gcagaccagg cccgaggccg gcagcgccgg
     7321 cgcgaacagg tcgccagtca tccagccgcc ctcgccttgt ccaggtagga caggatcgcc
     7381 tccgcggccc gccgcgccgt gtcctggcgg agggtgtgat gcagcgcggt gaagcgcgcc
     7441 tcgaccgcgg cgcggcgcgc gtcgtcggca aaccagtcgt cgatcgcggc ggcgaggtgt
     7501 tcggggtcgg cctcgtcctg cagcagctcg ggcaccacgg tctcgccgca caggatgttg
     7561 ggcagcccca cccagggcag gtaggccata cgcttcatga ggcggtactg ccacttgccg
     7621 atgcggtagg tgatcaccat cgggcgcttg agcagcgccg cttccaggct cgccgtgccg
     7681 ctcgccacca acaccacgtc ggcggcggtc atggcttcga ctgcgtggcc gaacagcatg
     7741 cggatcggca gctcgcccgc atcctgtcgg tgcagcgcct cctcgaagag ctggcgcgtc
     7801 tcgcgtgtgg cgagcggcac cagaaagagg cgctccggat cacgctcgtg caggatcttc
     7861 gcggtgccga tgaagatgtc ggccaggttg cgcacttcgg actgccggct gcccggcagc
     7921 atcgccacca cgcggcgctc ggccgctatg ccgaggcgtt cgcgcgcctc ggcacgatcg
     7981 ggttcgagcg ggaattcgtc ggcgagcggg tggccgacgt agctcaccgg cacgccggcg
     8041 cgctcgtaaa gctcgggctc gaaggggaac aggcacagca tgtgcgacac cgagcgcgcg
     8101 atgcgcttga tccgcccgcc ccgccaggcc cagatcgacg ggccgacgaa gtggatcgcg
     8161 gggatgccgg cgtcgcgcac cttgccctcg agccacaggt tgaagtcggg cgcatccaca
     8221 ccgatgaagg cgtcggggcg ctcggcgcgg atctgcccga gcaggtcgcg gcggatgccg
     8281 gagagctcgc ggtagcgctt gagcgcgtcg acgtagccat gcaccgcgag cagctcgcag
     8341 ggccagcgca cctcgaagcc ttcggcctgc atcttcggcc cgccgatgcc gaagaactcg
     8401 gcgtcgggca ggtggcggcg cagcgcgcgg atcaggtggc tcgcgagcag gtcgccggag
     8461 gtctccccgg cgaccatggc gatgcggacc ttcatgtcct gggaaacgcc atccgcgtca
     8521 tgctcagcgc acgatgccgc gaccggagtc ggcgatgaac tcggcgaagg cggcgacctc
     8581 ggcctgttcg gcggcgatct cggcgacgcg ctggcgcgcc tcgtcgaggc tcagcccggc
     8641 gcggtagagg gcgcggtagg cgcgcttgat ggcggcgatg ccttcggtcg aatagccccg
     8701 gcgcttgagg ccttcgctgt tgatgccgtg cggcttggcc gggttgcccg cgacggtcac
     8761 gaagggaggg agatcctgca gcagcacggt gccgacgccg cagaagctgt gcgcgccgac
     8821 acggcagaac tgatgcacgc cggtgaagcc gccgaggatc gcccagtcgc ccacatggac
     8881 gtgaccggcg agcgtggcgt tgttggcgaa gatggtgtgg tcgccgacct ggcagtcgtg
     8941 cgcgatgtgc acataggcca tgatccagtt gtcgttgccg acgcgggtga cgtgcgcgtc
     9001 ctggctggtg ccgacgttga acgagcagaa ctcgcggatc gtgttgcggt cgccgatctc
     9061 gagccgggtg ggctcggcgt cgtacttctt gtcctgcggg ctggcgccga tcgagcagaa
     9121 ctggaagatc tcgttgtcgc ggccgatgcg ggtgtggccc tcgaccacga cgtgcgggcc
     9181 gatgcgcgtg ccgtcgccga tctcgacgtg ctcgccgatc agcgaatagg ccccgacgct
     9241 gacgttggcg ccgagcttcg cacccggatg gacgatggcg gtgggatgga tcatagggtc
     9301 ttgatcgcgc acatgaggtc ggcttcggcc gcgagctcgc catcgacgct ggcgcgcgcc
     9361 ttgtacttgt agatgttgcg cttggcgtgg gtgatctcga cgtcgaagat cagctggtcg
     9421 cccggcacca ccggccgctt gaagcgcgcg ttgtcgatgc cggcgaagta caccaccgag
     9481 ttgtcgtcgg gcttcacccc ggtgctcttg aacgaaagca gcgcggcggc ctgcgccatg
     9541 gcctcgatga tcagcacgcc cggcatcacc gggtggtgcg gaaagtgtcc cgggaagaag
     9601 ggctcgttca tggtcacgtt cttcaggccg cgcgcacgca cgcccggctc gatctccagc
     9661 atgcggtcga cgagcaggaa ggggtagcgg tgcggcaggt actgcaggat ttccttgatg
     9721 tccatgatgg ctcagccctg cgagcggtcg tcgggaccgt cgctgtgttg ttcgagttgg
     9781 cggacgcgcc tggcgagcgc gtcgaggtgg cgcaggtggg agaagttctt cacccagtcg
     9841 ccatgggtct gcagcggcag attgctggtg tagacgccag gcttggtgat cgacttggcg
     9901 accagcgtcc acgccgagac cacgacgtcg tcggcgatgc tcagatgccc ggagatgccg
     9961 gcctggccgc cgatcatgca gcgcgcgccg atgcgtgcgc tgcctgcgac cccggcgcat
    10021 cccgccatga tggtgtgctc gcccacgtgc acgttgtggg cgatctggat gaggttgtcg
    10081 agcttgacgc cgtcgccgat cacggtgtcg tcgagcgcac cacggtccac cgtggtgttg
    10141 gcgccgatct cgacgtcgtt gccgaggacc acgcggccgg tctgcgggat cttgacccag
    10201 gccccggact tctcgcgcgc gaagccgaag ccgtcggcgc cgatgaccac gcccgagtgc
    10261 aggatgcagt cctcgccgat caggcaatcg tgatagacgg tgacgttggc gtagagccgc
    10321 gtgccgcggc cgatgcgggt gccgcgcccg acgtggcagt tggggccgat caccacgtcc
    10381 tcgccgacca ccacgtcttc ctcgatcgag gcgcccgaac cgacctgcac gctggaaggg
    10441 agcgtgctcg cgactgcggc ggtcggatgg atgccgggcc gcacggcggg cgggggattg
    10501 aacagctgcg cgacgcgggc gaagtacagg taggggtcgg cgctcaggat caggttgcgg
    10561 ccggcaagcg cctcgcgcag gtcgggcgtg acgatgagcg cgctcgcggc acactcgccg
    10621 acctgcgaca ggtatttgcg attggcgagg aaggcgaggt cgccgtccct cgccgtatcc
    10681 agcggcgcga cgcggccgac cgcgacgctg ccgtctcccg cgatctcgcc gcccaggcga
    10741 tcgaccagct cttgcagtcg gaacatcggg cggccggtct tacttggcgt cggacagggt
    10801 cttgatgacc ttgtcggtga tgtcgatgcg cgggttcgcg tacaccgctt cctggaagat
    10861 gatgtcgtag ttttcctgct cggcgatctc cttcaccgag cggttggcct tgtcgagcac
    10921 cgacgcgagt tcctcgttgc ggcgctggtt gaggtcctcg cggaactcgc gctgcttgcg
    10981 ctggaagtcg cggttgagct cgttgaacga acgctccttg ttgcggcggt cgctgtcgcc
    11041 catggtcggg ccgttacgct cgaggtcttc ctgcatcgac ttgaggtcgc gagcgatgcg
    11101 ctgcaactcc tggtcgcgct tctcgaattc cttctccagg cgctgctggg cgcgcacggc
    11161 gggagccgcc tcgcgcatca cgcgatcgga gttgacgaag ccgatcttgg tctcggcgaa
    11221 cgcggtgtgg gagaggccga gcagagcgac tgcgaccagg gagagggtac ggactttcaa
    11281 ttatgcctcc ggatgaaact gggttgccgg cagatcagaa cacgctgccg agctggaact
    11341 ggaaccgctg gacctcgtcg ttttcttcct tcttgagcgg atgaccgaag ctgaacttca
    11401 gcgggccgat cggcgagctc caggagaacg cgaggccggt actgtagcgc aggtcaccga
    11461 accgtacatc ctgctcgacg aagcttccac ccccgagcgg aacctcgtcc tcgccccaca
    11521 cgtaacccgc atcgaagaag gccgagatgc ggaaggaccg gtccttgcca gccccgggca
    11581 tcgggaagaa gaactcggca ttgccgacca ccttgcgggt gcccccggtg gaagtgatgt
    11641 cgccgtcggt atcctgatac ttgggtccga ccgagccctg gtcgaagccg cgcacagaac
    11701 cgatgccgcc gacgtagtag ttcttgtaga acgggacttc cttgccgccg aaacccttgg
    11761 cgtagcccac atcggcattg agcatgagcg catagtcgga accgatcggg aaccagtgct
    11821 gatactgata gccgagcttg ccgtagcgca ggtcgccgac cggaacagtg acctcaccgt
    11881 acaggcgctg atacaccccg ctgcgcgggt agacgaagct gtcgcgaccg tcgcgcgacc
    11941 agcccacggt gaggaccagg ctgtcgaccg tgcactcgcc cacgccgctg acgttgtcca
    12001 ggccgttctc gcgacagaaa tccttgtaca gcagcgggct gaggttgtag gtggtgatct
    12061 cg
//
LOCUS       DAOTIN010000097        11962 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_6365_length_11962_cov_8.841606, whole genome shotgun sequence.
ACCESSION   DAOTIN010000097 DAOTIN010000000
VERSION     DAOTIN010000097.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 11962)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 11962)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11962
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6365_length_11962_cov_8.841606"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..209)
                     /locus_tag="P5537_12790"
     CDS             complement(<1..209)
                     /locus_tag="P5537_12790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP protease specificity-enhancing factor
                     SspB"
                     /protein_id="HRV78960.1"
                     /translation="MTTISTKPYLLRAIWEWCVDQGFTPYLATLVDENTRVPPGYARD
                     GQIVLNLSPDATGQLQMANDFISFQG"
     gene            complement(280..876)
                     /locus_tag="P5537_12795"
     CDS             complement(280..876)
                     /locus_tag="P5537_12795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase N-terminal
                     domain-containing protein"
                     /protein_id="HRV78961.1"
                     /translation="MMNLYSGTTDPFSHRCRIVLFEKGMDFEVIDVDLYNKPEDIAVI
                     NPYNRVPVLVDRDLVLYEANIINEYIDERFPHPQLMPPDPIMRARARQLLHTFEQELF
                     THLEALEAAQKGVDKVRAHVRDHLTQLAPVFTKQKYMLGDEFSMLDVAIAPLLWRLEH
                     YGIELPKAAAPLMKYAERIFSRQGFIDALTPSEKVMRR"
     gene            complement(984..1739)
                     /locus_tag="P5537_12800"
     CDS             complement(984..1739)
                     /locus_tag="P5537_12800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c1"
                     /protein_id="HRV78962.1"
                     /translation="MKTRVINFIKRFAAVALFAPAVAMAAGASVHLDKAPVSTEPAAL
                     QHGAKLFVNYCMNCHSASFMRYNQLENIGLSESEIRDNLMFTGARVGDLMKIAMRPAE
                     SKVWFGAAPPDLTLIARQRASGDGSGADWLYTYLRQFYRDTERPTGWNNVVFENVGMP
                     HVFWQLQGEQVAKVAQNADGSKKVELSLAKPGTLSVQEYDKAVADLVSFLVWMGEPVA
                     EKRKSIGAIVLIFLAGMFVLSYALKKNYWKDIH"
     gene            complement(1736..3004)
                     /locus_tag="P5537_12805"
     CDS             complement(1736..3004)
                     /locus_tag="P5537_12805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004377661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bc complex cytochrome b subunit"
                     /protein_id="HRV78963.1"
                     /translation="MTTKSQAVLNWIDERFPLTSTWKAHLSEYYAPKNFNFWYFFGSL
                     ALMVLVIQIVTGIFLVMHYKPDASLNASGVPVAFASVEYIMREVPGGWLIRYLHSTGA
                     SAFFIVVYLHMFRGLLYGSYRKPRELIWIFGTLIFLALMAEAFMGYLLPWGQMSYWGA
                     QVIVNLFSAIPIIGPDLSLVIRGDFVIGDATLNRFFSFHVIAVPLVLIGLVLAHIVAL
                     HEVGSNNPDGVEIKKKKDATGKPLDGIPFHPYYTVKDIVGVVVFLFFFSAVVFFMPEG
                     GGYFLEYNNFIPADPLKTPPHIAPVWYFTPFYSILRAVTYPLFGLDAKFWGVVAMGAS
                     VVIIAFLPWLDRSPVKSIRYKGPIFKIALAIFLVCFFILGYLGVLAPTPGRTLVSQIC
                     SVLYFAFFLLMPWYSKLDPCKPEPERVNFK"
     gene            complement(3008..3601)
                     /gene="petA"
                     /locus_tag="P5537_12810"
     CDS             complement(3008..3601)
                     /gene="petA"
                     /locus_tag="P5537_12810"
                     /EC_number="7.1.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011764694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045275 - respiratory chain complex III
                     [Evidence IEA];
                     GO_function: GO:0008121 - ubiquinol-cytochrome-c reductase
                     activity [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_process: GO:0009060 - aerobic respiration [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinol-cytochrome c reductase iron-sulfur
                     subunit"
                     /protein_id="HRV78964.1"
                     /translation="MSVDQKMDSSRRTLLLATSAAGGVAAVATAVPFVASLTPSERAK
                     AAGAPVEADVSKLKPGEMMTVEWRGKPVWILRRTPEMLASLDKTDEKVSDPNSEEPQQ
                     PEYAKNKHRSIKPEYLVTVGICTHLGCSPSEKFKVGAEGGMAADWPGGFLCPCHGSLF
                     DLAGRVYSSMPAPTNLEIPPHQYLADTTILVGDDGKA"
     gene            complement(3787..4380)
                     /gene="recR"
                     /locus_tag="P5537_12815"
     CDS             complement(3787..4380)
                     /gene="recR"
                     /locus_tag="P5537_12815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HRV78965.1"
                     /translation="MSPSSLDELIEALRCLPGVGPKSAQRMAYHLLQRDQRGAARLGN
                     ALLHALEVLRHCARCNSFTEDEVCPRCANPRRDAALLCVVEMPADLAMIEQTQSYNGL
                     YYVLMGRLSPLDGVGPRELRLDKLIARATEEGVREVILATNFTNEGEATAHTVASLLS
                     ARGVKVSRLSRGVPVGGELEHTDIGTIGQALIERRAV"
     gene            complement(4392..4715)
                     /locus_tag="P5537_12820"
     CDS             complement(4392..4715)
                     /locus_tag="P5537_12820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004377656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HRV78966.1"
                     /translation="MMKGGIAGLMKQAQQMQENMKKMQDQLGSIEVEGQSGAGMVKVQ
                     MTCKYDVRRVSIDESVMDDREMLEDLVAAALNDAVRKVEAATQEKMASVTAGLNLPPG
                     MKLPF"
     gene            complement(4805..>5808)
                     /locus_tag="P5537_12825"
     CDS             complement(4805..>5808)
                     /locus_tag="P5537_12825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau C-terminal
                     domain-containing protein"
                     /protein_id="HRV78967.1"
                     /translation="AAEPGARTEAPAPAVAAAGGTAPTQAASPARVADAAAAGSRAPK
                     TAPEAAPAAAAQADSLPPAQHAVPPAPAAAAVAAAVTPAAAPARTAAAVEPPVRPAPA
                     ARESAQDVPPWEDLPPEAYADHDLPPPREARNGGEEGDSALARAQSGGFAPGRAEPRG
                     GDAHRRDDAPTRAAPLPLVRAPAPATPASAPGEAAPVASADAAALLALGDWRGLIRAL
                     GLGGLVRELAQHCEWVECGDGVLQLRLSTAHRHLLDMNRGAVERLQDLLGAALGRTLA
                     VRIAIGDIAGETPAQRDAIERQARHAEAVAALEADPFVRELIERFDATLVESTVRPL"
     assembly_gap    5809..5908
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<5909..7111)
                     /gene="dnaX"
                     /locus_tag="P5537_12830"
     CDS             complement(<5909..7111)
                     /gene="dnaX"
                     /locus_tag="P5537_12830"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HRV78968.1"
                     /translation="MSYQVLARKWRPKSFGTLVGQEHVVRALTHALATGRLHHAWLFT
                     GTRGVGKTTISRILAKALNCETGITAEPCGVCDACRAIDADRFPDYVEMDAASNRGVE
                     EMAALLDKAVYAPVQGRFKVYMIDEVHMLTGHAFNAMLKTLEEPPEHVKFILATTDPQ
                     KIPVTVLSRCLQFNLKQMPQGHIVDHLTRILQAEEVAFEPGALRHLAKAAAGSMRDAL
                     SLLDQAIAHGAGRVEEEQVSHMLGTVGDDHLYAVLDALAAGDVPALLAVADGMEARSL
                     SFDAALQALATLVHRIALAQYAPAAVADEVERARILGYVERFDAEFLQLAYQVAIHGR
                     DELPLAPDDYTGFTMTLLRLHAFRPEQPAALGGPGVRPGPDAGRARVPAAAGEGGGPA
                     MPPATAGGA"
     gene            7260..8030
                     /gene="cysQ"
                     /locus_tag="P5537_12835"
     CDS             7260..8030
                     /gene="cysQ"
                     /locus_tag="P5537_12835"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004320146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'(2'),5'-bisphosphate nucleotidase CysQ"
                     /protein_id="HRV78969.1"
                     /translation="MDNTAASRLLEALVPIVRAAGAAVMEVYRSDFAAREKADGSPLT
                     EADARAETLITSALLELRPDIPVVAEEAAAGSLQAAPGRRFWLVDPLDGTREFIHRNG
                     EFTVNVALIEDGEPVLGVILAPALGRLFLGAAGVGAFLEEAGQRRRIHCRRPPAAGLT
                     VVASRSHGDAAALDAFLAGRKVAALANAGSSLKLCLIAAGEADLYPRLGRTMEWDTAA
                     GHAVLAAAGGSVRTLAGEPLHYGKTGLENPHFVASGPD"
     gene            8282..8602
                     /locus_tag="P5537_12840"
     CDS             8282..8602
                     /locus_tag="P5537_12840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HRV78970.1"
                     /translation="MSSPPTPDAEEIRHALRQVMDPEVGMNIVDLGLIYRIDCAPGEL
                     YIEMTMTTPACPLSDMILDNIDAVLDPLLPPEVNIRVELVWDPPWSPAMMEEGARAHF
                     GWNG"
     gene            8599..9699
                     /locus_tag="P5537_12845"
     CDS             8599..9699
                     /locus_tag="P5537_12845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78971.1"
                     /translation="MSTLPPLARVPLLVLGLLSLLTGVFAGLARLGVEVPALAAMHAG
                     NHAALMICAFFGTVICLERAVALGGLWPYAGPAAAGAGGVLLLAGGPLPAAQLLFLIA
                     AATLLGGGIVVVRRQLALFTVMLAVGAACWLLGTLVWWSSGNVHAAVPLWLAFLILTI
                     AGERLELTRFLPARPTAAPSFVAVSALILAGALLAPFEEGVGHGLFAAGVLAMAAWLL
                     IFDIARHNARQQGLTRFIAICLLSGYVWLALGALAALGGGLAPASPLHDTTMHAIALG
                     FVFSMVFGHAAIIFPAVLKVKIPYHPAFYVPLALLHASLALRVAGSLVELPGLRSWGG
                     IANALTLAVFIATMIVSVIRGGRPPARRRRTG"
     gene            9902..10378
                     /locus_tag="P5537_12850"
     CDS             9902..10378
                     /locus_tag="P5537_12850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004374041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF411 domain-containing protein"
                     /protein_id="HRV78972.1"
                     /translation="MNRIPRPALLHKLARILPTLACGAALGLAAPAFASPDEVVMYKD
                     PNCGCCGKWAEHMRSAGFAVKEVASARMELVKQEAGVPEALGSCHTAKVGGYVVEGHV
                     PAADVRRMLAEKPAIRGLSAPGMPLGSPGMEGPYPAERYDVVSFDAQGRSAVFSKH"
     gene            complement(10375..11418)
                     /locus_tag="P5537_12855"
     CDS             complement(10375..11418)
                     /locus_tag="P5537_12855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HRV78973.1"
                     /translation="MEIDHLRQRLRALGARPSHEARLLRAWLQGHALDAGPRTESNRL
                     PKTVQAALPELEAELGALARVRSEHPGEDGIRLLVELADGQAVESVLLPRDGLCVSTQ
                     VGCAVGCVFCMTGKDGLLRQLDSGEIVAQVALARRLRRVHKVVFMGMGEPAHNLDAVV
                     EAIELLGTEGAVPHKNLVLSTVGDARVFERLPQMRVKPALALSLHTTRAELRSALLPR
                     GPRIDPAELVELGEAWARASGYPIQYQWTLIEGVNDGEDELEGIVRLLAGKYAVMNMI
                     PFNRVDGLDYRRPAAERAAEIARRLHRAGILTKLRQSAGQDVDGGCGQLRAREARLAF
                     VRREERRAARPPA"
     gene            11566..>11962
                     /locus_tag="P5537_12860"
     CDS             11566..>11962
                     /locus_tag="P5537_12860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002930131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HRV78974.1"
                     /translation="MTALRFEGAQDYVATPDLMLAVNAAIRLQRPLLIKGEPGTGKTM
                     LAEQVASALGLPLLQWHIKSTTKAQQGLYEYDAVSRLRDSQLGDDRVKDIGNYIVKGV
                     LWQAFEAEQPTVVLIDEIDKADIEFPNDLL"
BASE COUNT         1786 a         4167 c         4114 g         1795 t
ORIGIN      
        1 ccctggaagc tgatgaagtc gttggccatc tgcaactggc cggtggcgtc gggcgacagg
       61 ttgagcacga tctggccgtc gcgcgcgtaa ccgggcggca cgcgggtgtt ctcgtccacc
      121 agggtggcga ggtagggcgt gaagccctga tccacgcacc actcccagat ggcgcgcagc
      181 aggtaaggct tggtcgatat cgtagtcatc ggcgagtcat cgtatctacc ggcgcctgcg
      241 cgcgcaggcg cgctggcagg cgcggtcggg cgcggcggat cagcgccgca taaccttttc
      301 ggacggggtg agcgcgtcga tgaagccctg acggctgaag atgcgctcgg cgtacttcat
      361 cagcggcgcg gcggccttgg gcagctcgat gccgtaatgc tcgaggcgcc acagcagcgg
      421 cgcgatcgcg acgtcgagca tggagaactc gtcgccgagc atgtacttct gcttggtgaa
      481 caccggcgcg agctgggtga ggtggtcgcg cacgtgggca cgcaccttgt ccacgccctt
      541 ctgcgcagcc tccagcgcct ccaggtgggt gaacagctcc tgttcgaagg tgtgcagcag
      601 ttggcgggcg cgcgcacgca tgatcgggtc gggcggcatc agctgcggat gcgggaagcg
      661 ctcgtcgatg tactcgttga tgatgttggc ctcgtagagc acgaggtcgc gatcgaccag
      721 caccggcacg cggttgtagg ggttgatgac ggcgatgtct tcgggcttgt tgtagaggtc
      781 gacgtcgatg acctcgaagt ccatgccctt ctcgaacagc acgatccggc aacggtgact
      841 gaagggatcg gtcgtgccgg aatacaggtt catcatggtg ttgcgactcc ggaattcaaa
      901 agcaaaagcg caccacgcgg gtccgcgtgg tgcgtctggg tcaggaccgc gctagacggc
      961 ccggagggcc gcggcgacag aaatcaatga atgtccttcc agtagttctt cttcagcgca
     1021 tagctgagca cgaacatgcc ggcgaggaag atcagcacga tcgcgccgat cgacttacgc
     1081 ttctcggcga ccggctcgcc catccagacc aggaaggaga cgaggtcggc aaccgccttg
     1141 tcgtactcct gcaccgagag cgtgcccggc ttggcgaggg agagctcaac cttcttgctg
     1201 ccgtcggcgt tctgggcgac cttggcgacc tgctcgccct ggagctgcca gaacacgtgc
     1261 ggcatgccga cgttctcgaa cacgacgttg ttccagcccg tggggcgctc ggtgtcgcgg
     1321 tagaactggc gcaggtacgt gtacagccag tcggcaccgc tgccgtcgcc cgaggcgcgc
     1381 tggcgcgcga tcagggtcag gtcgggaggc gccgcaccga accacacctt ggactccgcc
     1441 ggacgcatcg cgatcttcat caggtcgccg acacgcgcgc cggtaaacat caggttgtcg
     1501 cggatttccg actcggacag gccgatgttc tcgagctggt tgtagcgcat gaagctcgcg
     1561 ctgtggcagt tcatgcagta gttgacgaac agcttggcgc cgtgctgcag cgcggccggc
     1621 tcggtgctca ccggtgcctt gtccagatgc acgctggcgc cggcggccat cgccacggcc
     1681 ggcgcgaaca gcgccacagc cgcgaaccgc ttgatgaagt tgatcactcg cgttttcatt
     1741 tgaagttcac cctttccggt tcgggtttgc acgggtcgag tttgctgtac cacggcatca
     1801 gcaggaagaa ggcgaaatac agcaccgagc agatctgcga gaccagcgta cggcccgggg
     1861 tcggagccag cacgccgagg tagccgagga tgaagaagca caccaggaag atcgccaggg
     1921 cgatcttgaa gatcgggccc ttgtagcgga tcgacttcac cgggctgcgg tccagccacg
     1981 gcaggaaggc gatgatcacc accgaggcac ccatggcgac cacgccccag aacttcgcgt
     2041 cgagaccgaa cagcgggtag gtcaccgcgc gcaggatcga gtagaagggg gtgaagtacc
     2101 acaccggcgc gatgtgcggc ggagtcttca gcgggtcggc cgggatgaag ttgttgtact
     2161 ccaggaagta gccgccgccc tcgggcatga agaacacgac cgcgctgaag aagaacagga
     2221 agaccaccac gccgacgatg tccttcaccg tgtagtacgg gtggaagggg atgccgtcca
     2281 gcggcttgcc ggtcgcgtcc ttcttcttct tgatctcgac gccgtcgggg ttgttggagc
     2341 cgacttcgtg cagcgcgacg atgtgcgcga gcacgagacc gatcagcacc agcggcaccg
     2401 cgatgacgtg gaaggagaag aaacggttca gcgtggcgtc gccgatgacg aagtcgccgc
     2461 ggatcaccag ggagaggtcc ggtccgatga tcgggatcgc cgagaacagg ttcacgatca
     2521 cctgggcgcc ccagtaggac atctggcccc agggcagcag gtagcccatg aaggcctcgg
     2581 ccatcagcgc caggaagatc agcgtgccga agatccagat cagctcgcgc ggcttgcgat
     2641 aggaaccgta gagcaggccg cggaacatgt ggagatagac cacgatgaag aaggccgacg
     2701 caccggtcga gtgcaggtag cggatcagcc agccacccgg cacctcgcgc atgatgtact
     2761 cgacgctggc gaacgcgacc ggcacgcccg aggcgttgag cgaagcgtcc ggcttgtagt
     2821 gcatgaccag gaagatgccg gtgacgatct ggatcaccag caccatcagc gccagcgagc
     2881 cgaagaagta ccagaagttg aagttcttcg gcgcgtagta ctcggacaga tgcgccttcc
     2941 aggtggacgt gagcgggaaa cgctcatcga tccagttgag aacggcttgt gatttggtag
     3001 tcatcgctta tgccttcccg tcatcgccaa caagaatggt ggtgtccgcg aggtactggt
     3061 gcggcggaat ctcgaggttg gtcggcgccg gcatgctgct gtacacccgc ccagcgaggt
     3121 cgaacagcga gccatgacag gggcacagga agccgcccgg ccagtccgcg gccatgccac
     3181 cctcggcacc gaccttgaac ttctcggagg gcgagcagcc gaggtgggtg cagatgccga
     3241 ccgtgaccag atactccggc ttgatcgagc ggtgcttgtt cttggcgtac tcgggctgct
     3301 gcggctcctc ggagttgggg tcgctgacct tttcgtccgt cttgtcgagc gaggcgagca
     3361 tctcgggcgt gcggcgcagg atccacaccg gcttgccacg ccactccacc gtcatcatct
     3421 cgcccggctt cagcttgctg acgtccgcct ccaccggcgc accggccgcc ttggcgcgtt
     3481 cggacggcgt caggctggcg acgaacggca ccgcggtcgc caccgcggcg acaccgcccg
     3541 cggcggacgt cgccagcagc agggtgcggc ggctgctgtc cattttctga tcaacgctca
     3601 tgagcctctt cccaaaaagg aaaacgaaag acctggatac aaataaccat ccgattatat
     3661 cgaagacgtc gcagcagaga aagcgcagcg ggccgatcgc cagccggaac aaggctttcg
     3721 gcacgaaaac agacaccggt cagggcgcgc ggcgggcctg tgtcgctgcg ctgcagcagc
     3781 gccgaatcag accgctcgcc gctcgatcag cgcctgcccg atggtgccga tgtcggtgtg
     3841 ctcgagctcg ccgccgacgg gtacgccgcg cgacagccgg ctgaccttga cgccgcgcgc
     3901 cgagagcagg ctggccacgg tgtgcgcggt agcctcgccc tcgttggtga agttggtcgc
     3961 caggatgacc tcgcgcaccc cctcttcggt ggcgcgcgcg atcagcttgt cgaggcgcag
     4021 ctcgcgcggc cccacaccgt cgagcgggga cagccggccc atcaacacat agtagaggcc
     4081 gttgtaggac tgcgtctgct cgatcatggc gagatcggca ggcatctcca ccacgcacag
     4141 cagcgcggcg tcgcggcgcg gattcgcaca gcgcgggcac acctcgtcct cggtgaagct
     4201 gttgcagcgt gcgcagtgac gcagcacctc gagcgcatgc agcagggcat tgcccagccg
     4261 tgccgcgccg cgctggtcgc gctgcagcag gtggtaggcc atgcgctgcg ccgacttggg
     4321 gccgaccccg ggcaggcagc gcagcgcctc gatcagctcg tcgaggctgg agggcgacat
     4381 cggcgcgccg ctcagaacgg cagcttcatg cccggcggca ggttcagccc ggcggttacg
     4441 ctcgccatct tctcctgggt ggcggcctcg accttgcgca cggcgtcgtt gagcgcggcg
     4501 gcgacgaggt cctcgagcat ctcgcggtcg tccatgacgg actcgtcgat cgacacgcgg
     4561 cgcacgtcgt acttgcaggt catctgcacc ttgaccatgc cggcgccgga ctggccttcg
     4621 acctcgatcg agccgagctg gtcctgcatc ttcttcatgt tttcctgcat ctgctgggcc
     4681 tgcttcatca ggcccgcgat accgcctttc atcatgatgg tgttctccgt tggatcggtt
     4741 gtcggcttgc ttcgaccgga gctggcgcac catggcgggc gcgcctcccg gcctcgaaag
     4801 ggaatcagag aggcctcacc gtgctctcga cgagggtggc gtcgaagcgc tcgatcagct
     4861 cgcgcacgaa gggatcggcc tcgagcgctg cgaccgcctc ggcgtggcgg gcctggcgct
     4921 cgatcgcgtc gcgctgcgcg ggggtctcgc cagcgatgtc gccgatcgcg atgcgtaccg
     4981 cgagcgtgcg cccgagcgcg gcgccgagca ggtcctgcag gcgctcgacg gcgccacggt
     5041 tcatgtcgag caggtggcgg tgcgcggtgg acaggcgtag ctgcagcacg ccgtcgccac
     5101 actcgaccca ttcgcagtgc tgggcgagtt cgcgcaccag cccgccgagc ccgagcgcac
     5161 ggatcagccc gcgccagtcg ccgagcgcga gcagggccgc ggcgtccgcg ctggcgacgg
     5221 gcgcggcctc gcccggggcg gacgcaggcg tcgccggcgc gggcgcgcgc accaagggaa
     5281 ggggcgcagc ccgcgtcggg gcgtcgtccc tccggtgcgc gtcaccacca cgtggctcgg
     5341 cgcgccccgg ggcaaatccg ccggactgtg cccgcgccaa ggcggaatcg ccctcctcgc
     5401 cgccattgcg cgcctcgcgc ggcggcggca ggtcatggtc ggcataggcc tcgggcggga
     5461 gatcttccca gggcgggacg tcctgcgcgc tttcgcgggc agcgggcgcc gggcgcacgg
     5521 ggggctcgac cgccgcggcc gtgcgcgccg gcgctgcggc tggcgtcacc gcagcggcca
     5581 ccgctgccgc ggcgggcgca ggggggacgg cgtgctgcgc cggcggaagg gagtcggcct
     5641 gcgcggctgc agccggcgca gcctcgggcg cggtcttcgg cgcgcgggag cccgccgcag
     5701 cggcgtcggc aacccgagcg gggctggccg cctgtgtggg ggcggtgccc ccggccgcag
     5761 cgacggccgg ggcaggcgct tcggtccgcg cgcccggctc cgccgcgcnn nnnnnnnnnn
     5821 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5881 nnnnnnnnnn nnnnnnnnnn nnnnnnnncg cgccaccggc cgtcgcgggc ggcatcgccg
     5941 gtccgccgcc ctcgcccgcc gctgcgggca cgcgcgcgcg cccggcgtcc gggcccggac
     6001 gcacacccgg cccgccgagc gcggccggct gctccgggcg gaaggcatgg aggcgcagca
     6061 gggtcatcgt gaagccggtg taatcgtccg gcgcgagcgg cagctcgtcg cggccgtgga
     6121 tggcgacctg gtaggcgagc tggaggaatt cggcgtcgaa gcgctcgacg tagccgagga
     6181 tacgcgcgcg ctcgacctcg tcggcgaccg cagccggcgc gtactgggcg agcgcgatgc
     6241 gatgcaccag cgtggccagc gcctgcagcg cggcatcgaa ggacaggctc ctcgcctcca
     6301 tgccgtcggc gaccgcgagc agcgccggca cgtcgcccgc ggcgagcgca tcgagcaccg
     6361 cgtacaggtg gtcgtcgcca acggtgccga gcatgtggct gacctgctcc tcctcgacgc
     6421 ggcccgcgcc atgcgcgatc gcctggtcga gcagcgacag cgcgtcgcgc atcgagcccg
     6481 ccgcggcctt ggcgaggtgg cgcagcgccc ccggctcgaa cgccacctcc tcggcctgca
     6541 ggatgcgcgt cagatggtcg acgatgtgcc cctgcggcat ctgcttgagg ttgaactgca
     6601 ggcagcgcga cagcaccgtc accgggatct tctgcgggtc ggtggtggcg aggatgaact
     6661 tcacatgctc cggcggctcc tcgagcgtct tcagcatggc gttgaaggca tgcccggtga
     6721 gcatgtggac ttcgtcgatc atgtagacct tgaagcgccc ctgcaccggc gcatacaccg
     6781 ccttgtcgag cagcgccgcc atctcctcga cgccgcggtt cgaggccgcg tccatctcga
     6841 cgtagtcggg gaagcggtcg gcgtcgatcg cgcggcaggc gtcgcacacg ccgcagggct
     6901 cggcggtgat gccggtctcg cagttgagcg ccttggcgag gatgcggctg atcgtggtct
     6961 tgcccacgcc gcgcgtgccg gtgaacagcc aggcgtgatg cagccgcccg gtggcgagcg
     7021 cgtgcgtcag tgcacgcacg acgtgctcct gaccgaccag cgtgccgaag gatttcggcc
     7081 gccacttgcg tgcgaggacc tgatagctca tggcgggcga ttctagcaga gcggcgcgcg
     7141 gcggcccgcg cgctcgacgg ctcatccgtc acggtggcgc ggaggcgcgc cctgcggcac
     7201 gtgctccccc cttggcggtt agactggccg ctcctctgcc gccctgcact ccccgcccga
     7261 tggacaacac cgccgcctcc cgcctgctcg aagccctcgt cccgatcgtc cgtgccgccg
     7321 gtgctgcggt gatggaggta taccgctccg acttcgccgc tcgggaaaag gcggacggat
     7381 ctccgcttac cgaagccgat gcccgcgccg agacgctcat cacgtccgcg ctcctcgagc
     7441 tgcggccgga cattccggtc gtcgccgagg aagcggccgc cggcagcctc caggcagcgc
     7501 cggggcggcg cttctggctc gtcgacccgc tcgacggtac gcgtgagttc attcaccgca
     7561 acggcgaatt caccgtcaac gtcgcgctga tcgaagacgg cgagccggtg ctcggcgtga
     7621 tactcgcccc cgcgctcggg cgcctcttcc tcggtgccgc aggcgtcggc gccttcctcg
     7681 aagaggcggg ccagcgcagg cggatccact gccgaaggcc gccagccgcc ggcctcaccg
     7741 tggtcgccag ccgctcgcac ggcgacgccg cggcgctcga cgccttcctc gccggccgca
     7801 aggtcgccgc gctcgccaat gccggctcct cgctcaagct gtgcctgatc gcggccggcg
     7861 aggcggacct ctacccgcgc ctgggccgca ccatggagtg ggacaccgcc gccggacacg
     7921 ccgtgctcgc cgctgccggc ggcagcgtcc gcaccctcgc gggcgagcca ctgcactacg
     7981 gcaagaccgg cctagaaaac ccgcacttcg tcgccagcgg gccggattga ggccggcgcc
     8041 ggaggcggag ccgggtgctg cgccgacgca atcgcccccg gcccgggatc gcgggacatc
     8101 gcgcgcggct gcgcgtcatg cgcgcccgcc ggaatcggcg agacagccgg cgggcggcgc
     8161 acattgaacg tatcatcgca ctcgcccaca atgcgtgtcg gcctgcggcg tgccgcccaa
     8221 gcccttcagc ccggcaagca gccgatccgg gcgcgacgca accgactctg gaacccgacg
     8281 catgagctcc cccccgaccc ccgacgccga agagatccgc cacgccctgc gccaggtcat
     8341 ggacccggag gtcggcatga acatcgtcga cctcggcctg atctaccgca tcgactgcgc
     8401 acccggcgag ctctacatcg agatgacgat gaccacgccg gcctgcccgc tgtccgacat
     8461 gatcctcgac aacatcgacg cggtgctcga ccccctgctg ccgcccgagg tgaacatccg
     8521 cgtcgagctg gtatgggatc cgccgtggtc gccggcgatg atggaggaag gcgcgcgcgc
     8581 gcacttcggc tggaacggat gagcaccctg cccccgctcg cccgcgtgcc cctgctggtg
     8641 ctcgggctcc tgtcgctgct caccggcgtg ttcgccggcc tcgcccgcct gggcgtggag
     8701 gtgccggcac tcgccgcaat gcacgcgggc aatcacgcgg cgctgatgat ctgcgccttc
     8761 ttcggcaccg tgatctgcct cgagcgtgcg gtcgcactcg gcggcctgtg gccctacgcc
     8821 gggccggccg ccgccggcgc gggcggcgtg ctgctgctcg ccggcggccc gctgcctgcg
     8881 gcgcagctcc tgttcctgat tgccgcggcg accctgctcg gcggtggcat cgtggtggtg
     8941 cgccgccagc tcgcgctgtt caccgtgatg ctcgcggtgg gcgcggcgtg ctggctgctc
     9001 ggcaccttgg tgtggtggtc cagcggcaac gtgcacgcag ccgtgccgct gtggctcgcc
     9061 ttcctgatcc tgacgatcgc cggcgaacgc ctggagctca cccgcttcct gcccgcgcgc
     9121 ccgaccgcgg cgccgagctt cgtcgcggtc agcgcgctga tcctcgccgg cgccctgctc
     9181 gcaccgttcg aagaaggcgt cggccacggc ctcttcgccg ccggcgtgct ggcgatggcg
     9241 gcctggctgc tgatcttcga catcgcccgc cacaatgccc gccagcaggg gctgacccgc
     9301 ttcatcgcga tctgcctgct gtcgggctat gtgtggctgg ccctcggcgc gctcgctgcg
     9361 ctcggcggcg ggctcgcgcc cgcatccccg ctgcacgaca ccacgatgca cgcgatcgcg
     9421 ctcggcttcg tgttctcgat ggtgttcggc cacgccgcga tcatcttccc ggcggtgctc
     9481 aaggttaaga tcccctacca cccggccttc tacgtgccgc tcgcgctgct gcacgcctcg
     9541 ctcgcgctgc gcgtggcagg gagcctggtc gagcttcccg ggctgcgcag ctggggcggg
     9601 atcgcgaacg cgctgacgct ggcggtgttc atcgccacca tgatcgtcag cgtgatccgc
     9661 ggcggacgcc cgccggcgcg ccggcggcgc accggctgaa gccgcacgcc gccgcggcgc
     9721 agccgattac attttcgtaa gcatgtgccg gcgcggggcg gggaacggca caattccgcc
     9781 atcgagacct tgcccggcgg acgcctgctc gcggacgtcg cctcgcgtgc cagcggcgcc
     9841 ggaacctcgc gccgcgcacc ctggtccgat cccctgtgaa acctcccggg aaccccgcac
     9901 catgaaccga attccccgcc ccgcgctcct gcacaagctc gctcgcatcc tccccacgct
     9961 cgcctgcggc gccgcgctcg gcctggccgc gcccgccttc gccagccccg acgaggtcgt
    10021 catgtacaag gaccccaact gcggctgctg cggcaaatgg gccgagcaca tgcgcagcgc
    10081 cggcttcgcc gtgaaggagg tcgccagcgc gcgcatggag ctggtcaagc aggaagccgg
    10141 cgtgcccgag gccctcggct catgccacac cgcgaaggtg ggtggctatg tcgtagaggg
    10201 ccacgtgccg gcggccgacg tacgccggat gctggccgag aagccggcga tccgcggcct
    10261 ctccgcgccc ggcatgccgc tcggctcgcc cggtatggaa ggcccctacc ccgccgagcg
    10321 ctacgacgtg gtgagcttcg acgcgcaggg gcgcagcgcg gtgttctcga agcactaggc
    10381 gggcggccgc gccgcgcgcc gctcctcgcg gcgcacgaag gcgagcctgg cctcgcgcgc
    10441 gcgcagctgc ccgcagccgc cgtccacatc ctgcccggcg gactgcctca gcttggtgag
    10501 gatgccggcg cggtgcagac ggcgggcgat ctcggccgcg cgctccgccg ccgggcggcg
    10561 gtagtcgagc ccatcgacgc gattgaacgg aatcatgttc atcaccgcgt acttgcccgc
    10621 gagcaggcgc acgatgccct cgagctcgtc ctcgccgtca ttcaccccct cgatcagcgt
    10681 ccattgatac tggatcgggt agccgctcgc gcgcgcccag gcctcgccga gctcgaccag
    10741 ctcggccggg tcgatgcgcg ggccgcgcgg cagcagcgcg ctgcgcagct ccgcgcgcgt
    10801 ggtgtgcagc gacagcgcca gcgccggctt gacgcgcatc tgcggcaggc gctcgaagac
    10861 gcgcgcatcg cccaccgtcg acagcaccag gttcttgtgc ggaaccgcgc cctcggtgcc
    10921 gagcagctcg atcgcctcga ccaccgcgtc gaggttgtgc gcgggctcgc ccatgcccat
    10981 gaacaccacc ttgtgcaccc ggcgcaggcg gcgcgcgagc gccacctggg cgacgatctc
    11041 gccgctgtcg agctggcgca gcaggccgtc cttgccggtc atgcagaaca cacagccgac
    11101 cgcgcagccg acctgggtcg acacgcacag gccgtcgcgc ggcagcagca cgctctcgac
    11161 cgcctggccg tcggcgagct cgaccagcag ccggatgccg tcctcgccgg ggtgctcgga
    11221 gcgtacgcgg gcgagcgctc cgagttccgc ctcgagttcg ggcagcgcag cctgcacggt
    11281 cttgggcagg cggttggatt cggtgcgcgg gccggcgtcg agcgcatgcc cctgcagcca
    11341 ggcgcgcagc agccgggcct cgtggctggg gcgggcgccg agcgcgcgca ggcgctggcg
    11401 gaggtgatcg atttccatgg cgcgcgatgc tagcacccga gaggggcgag agcatccgcc
    11461 gcggggcaac accgccgccg tccataccac cgtcgacgcc gctccggctg cccgtccgca
    11521 gtgcccggcc ctataatcgc ctgcatccga cacgaggaat gccgcatgac cgcactacgc
    11581 ttcgaaggcg cccaggacta cgtcgccacc cccgacctga tgctcgcggt caacgcggcg
    11641 atccgcctgc agcgcccgct gctgatcaag ggcgagcccg gcaccggcaa gaccatgctc
    11701 gccgagcagg tcgcctccgc tctcggactg ccgctgctgc agtggcacat caagtcgacc
    11761 accaaggcgc agcagggcct ctacgaatac gatgcggtct cgcgcctgcg cgactcgcag
    11821 ctcggcgatg accgcgtcaa ggacatcggc aactacatcg tcaagggcgt gctgtggcag
    11881 gccttcgagg ccgagcagcc gaccgtggtg ctgatcgacg agatcgacaa ggccgacatc
    11941 gagttcccca acgacctgct gc
//
LOCUS       DAOTIN010000098        11865 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_6424_length_11865_cov_8.953006, whole genome shotgun sequence.
ACCESSION   DAOTIN010000098 DAOTIN010000000
VERSION     DAOTIN010000098.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 11865)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 11865)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11865
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6424_length_11865_cov_8.953006"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..386
                     /locus_tag="P5537_12865"
     CDS             <1..386
                     /locus_tag="P5537_12865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pyridine nucleotide-disulfide oxidoreductase"
                     /protein_id="HRV78975.1"
                     /translation="GFAGGGWLEVDKSTLRHRRFPNVFGIGDINGTPKGKTAATVKKS
                     TPLVVQNLIDVIAGREPSQRFDGYTSCPLLVREGAALLIEFDYENRLIPSLPAIDPLQ
                     DSYFAWVMKIRLLKPAYMAVAKGRV"
     gene            399..734
                     /locus_tag="P5537_12870"
     CDS             399..734
                     /locus_tag="P5537_12870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV78976.1"
                     /translation="MYEIWLTLNILYELGLQYLPVVIGTALLWLVLMAVAAARGRAGW
                     GAALKPAIAVAVVVTAITFFITPGMTQSSFANMGYWVDWGNLLLYAAAFGAVGGALAW
                     PLAAMMRRA"
     gene            816..1364
                     /locus_tag="P5537_12875"
     CDS             816..1364
                     /locus_tag="P5537_12875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HRV78977.1"
                     /translation="MKRLLIATALGIASLAAQAADIAISAQDTYAKIQSNERNVLFID
                     VRDPVEIMFVGFADAVHANVPFMMVDRTQWNAEKGVFRLYRNPDFINQVKLQLARRGL
                     SADAEIITMCRSGSERGEPSAAFLRENGFPNARYVVDGFQGSALKEGPQAGFRLKNGW
                     QNSGLPWSAKMNADKMHRVDRP"
     gene            1482..1922
                     /locus_tag="P5537_12880"
     CDS             1482..1922
                     /locus_tag="P5537_12880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HRV78978.1"
                     /translation="MSLLAQLKKDSMLARKAADGIRATLLSTLIGEAEMVGKNAGNRE
                     STDDEVQQTIRKFLKNNQEALAVIKDADRRTALEQESAILVAYLPPMASEAEVKAFIA
                     DTVAGLAERSPKQMGAVMGALKAKYGSGFDAKQANAWVKEALTG"
     gene            complement(2064..3881)
                     /gene="uvrC"
                     /locus_tag="P5537_12885"
     CDS             complement(2064..3881)
                     /gene="uvrC"
                     /locus_tag="P5537_12885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HRV78979.1"
                     /translation="MTDPTSPPAFDPKPFLRTLTEEPGVYRMIGADDRVLYVGKAKNL
                     KRRVSSYFQKTVSSPRIAMMVAQVLRVDITATRSEAEALILENNLIKSLAPRYNILFR
                     DDKTYPYIELSADEYPRLAYHRGAFTKGARYFGPFPNAWAVRESIHLLQKTFQLRTCE
                     NTVFANRSRPCLLHQIKRCTAPCVGLIEPEAYAADVRLATRFLDGQASEVIDDLTNRM
                     QAAAERLAFEEAAACRDQVRVLQAVLHKQFVDSRKDEDVDVLAAIEADGLTCVNIAMV
                     RGGRHLGDRPQFPSGAAVSGAMDSLLAFVEQHYSQHPIPARILVNLPPEAVKETLAEI
                     TERPPGVVSPRFAAEKAWMEMAEKNAHLAIQARARDTGRIEQRLEALRSALDLDEAPQ
                     RIECFDISHTMGEATVASCVVCEAGAMKRAEYRRYNITGITGGDDFAAMRQALERRYG
                     KVAAGEGVCPDLILIDGGKGQVSAARAILAEVGLEAVAMVGVAKGEGRKAGLETLIFP
                     DGREGLALGGESAALHLIVEIRDEAHRFAITGHRARRGKARVGSKLEDIPGVGPSRRR
                     NLLAAFGGLDGVREATVEDLCRVEGVSRKLAEQIHAALR"
     gene            complement(3928..5073)
                     /gene="nagZ"
                     /locus_tag="P5537_12890"
     CDS             complement(3928..5073)
                     /gene="nagZ"
                     /locus_tag="P5537_12890"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HRV78980.1"
                     /translation="MNAPVRRPRGPVMIDVAGTALTDEERERLLDPLVGGVILFARNY
                     TDSDQLRALTADLRALRDPALIIAVDHEGGRVQRFRTDGFTRLPSMRSLGALWEQDHL
                     AALEAARATGFVLASELRAHGVDLSFTPVLDLDYGCCRAIGNRAFHRDPQVIAALAQA
                     LVAGMAEAGMGAVGKHFPGHGFVEADSHHDVPVDERDFDTVWNEDIAPYRHRLGRQLA
                     GVMPAHVIYPKADPSAEPQPAGFSPFWLKDVLRGRLGFRGVIFSDDLNMEGARVAGDI
                     VGRAKAAYAAGCDMLLVCNRPDLAAELLDRWAPEPDADHLARLAAITPAVAPPAWLAD
                     PFVLELHTAYLQARERVGTVHDDTSTAATMTAAAIGEQRTEILRKEG"
     gene            complement(5093..5470)
                     /gene="acpS"
                     /locus_tag="P5537_12895"
     CDS             complement(5093..5470)
                     /gene="acpS"
                     /locus_tag="P5537_12895"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HRV78981.1"
                     /translation="MIHGIGTDLVQLRRMREALERHGERFALRILAASEVEAWRAHRD
                     PARFLAKRFAAKEAFGKALGTGVAVPATLHAVAVVHDARGKPEYRYDERLAAHMRDNA
                     LRAHLSISDEDEHIVAFALIERA"
     gene            complement(5668..6420)
                     /locus_tag="P5537_12900"
     CDS             complement(5668..6420)
                     /locus_tag="P5537_12900"
                     /EC_number="2.6.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033856 - pyridoxine 5'-phosphate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine 5'-phosphate synthase"
                     /protein_id="HRV78982.1"
                     /translation="MIELGVNIDHVATLRQARRTWEPDPVWAAVEAHLGGADGITIHL
                     REDRRHIGDEDVRRLAELTQVKLNLEMAATDEMVAIACRTKPQMAMLVPEGRHEITTE
                     GGLDVLSQEARLKDVIARLADAGIVTSVFIDAEPAQIEAAARIGARVCEIHTGPYAHA
                     FHAAGRDAEAPAVLGELEKIRTAGELVRRLGMRFNAGHALNYYNVEPIARLHGIRELH
                     IGHSIVSRAVFVGLRAAVAEMKRLMREAAQQA"
     gene            complement(6420..7178)
                     /gene="recO"
                     /locus_tag="P5537_12905"
     CDS             complement(6420..7178)
                     /gene="recO"
                     /locus_tag="P5537_12905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HRV78983.1"
                     /translation="MAGAKQRIEQQPAWVLHTYPWRETSLIVEIFAREFGRVALVAKG
                     ARRPHSQLRGVLLAFQPLWMDWSGGGEVKTLVRAEWQGGQPLLTGRALICGYYLNELL
                     VRLTAREDAHARLFDAYAEAVRALGRGAPESPILRRFELALLQDLGYEAGLAHEGDSG
                     EPVRPEGRYLYIIERGPVRLEVLEEEGASLDPAALGEQPLLSGQTLLDMAAGDFSRAE
                     TLAQSKQLLRMLINHTLGGQPLQSRRVLKELQEL"
     gene            complement(7194..8123)
                     /gene="era"
                     /locus_tag="P5537_12910"
     CDS             complement(7194..8123)
                     /gene="era"
                     /locus_tag="P5537_12910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HRV78984.1"
                     /translation="MTEVPQDPSSDEPTGEGGFRAGFVAIVGRPNVGKSTLLNRLIGQ
                     KISIVSSKAQTTRHRVTGILTEAGAQFVFVDTPGFQTHHRNALNRSMNRTVSQVLADV
                     DLVFFVIEAGRFTEDDRKVLAVIPEASKVILVINKVDQLKDKARLLPFIAQVREARDF
                     TEIVPLSAEKGRNVDELVKAATPLLPVATPMFEEDEITDRSERFLASEFLREKLFRLL
                     GDELPYGIAVEIEKFEVEGNLRRIYAAVIVDKPGHKSMVIGKGGEKLKRISSEARVEL
                     EKLFDGKVFLEVWVKVKSGWADDERALKSLGYE"
     gene            complement(8120..8791)
                     /gene="rnc"
                     /locus_tag="P5537_12915"
     CDS             complement(8120..8791)
                     /gene="rnc"
                     /locus_tag="P5537_12915"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002930005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HRV78985.1"
                     /translation="MMPDRLQARLGHAFADRRLLEEALTHRSFGQPNNERFEFLGDAI
                     LDCVVSIALFGRFGELREGELSRVRASLVRQDTLHRLALELELGDCLRLGEGELKSGG
                     SRRPSILADALEALFAAVYLDAGFEAAKGVIDRLYAPLIAEVDPGKPSKDAKTALQEW
                     LQARRIAVPTYTMVEIVGEAHAQEFEVACEIPKLAVRTLGRGPSRRIAEQQSAELALA
                     AVRKK"
     gene            complement(8796..9158)
                     /locus_tag="P5537_12920"
     CDS             complement(8796..9158)
                     /locus_tag="P5537_12920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4845 domain-containing protein"
                     /protein_id="HRV78986.1"
                     /translation="MKMHSQRGLTLLGVLVAGVIAAFVLVVGFRTVPVFNEYFAIKRI
                     LGVLADEADKGASLIELRRGFDRRGQIDDIHSVSGSDLNIDKSGPRTVIEVEYTRKVP
                     LLANVSLSIDLHPSSASR"
     gene            complement(9171..9959)
                     /gene="lepB"
                     /locus_tag="P5537_12925"
     CDS             complement(9171..9959)
                     /gene="lepB"
                     /locus_tag="P5537_12925"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HRV78987.1"
                     /translation="MNFALILLLLLIATGVLWFLDRFHARKLRPAGTPDPWWVEYGAS
                     FFPVILIVFGLRSFVVEPFKIPSGSMIPTLLVGDFILVNKWTYGIRLPVINQKIIEVN
                     DPKRGDVMVFRYPADPSMDYIKRVVGLPGDRVEYIDKRLVINGEAVPIREDGSYLHPD
                     RLYYSPRYVEKLGEVEHSVLIERDAPAYVPQVLNFPGREHCTYVHAGVRCTVPAGHYF
                     VLGDNRDASSDSRVWGFVPEQNIVGRAFFIWFNFGDMKRIGGFD"
     gene            complement(10002..11798)
                     /gene="lepA"
                     /locus_tag="P5537_12930"
     CDS             complement(10002..11798)
                     /gene="lepA"
                     /locus_tag="P5537_12930"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018992321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HRV78988.1"
                     /translation="MKHIRNFSIIAHIDHGKSTLADRLIHFCGGLSEREMEEQVLDSM
                     DIERERGITIKAQTAALHYKAKDGQVYNLNLIDTPGHVDFSYEVSRSLAACEGALLVV
                     DASQGVEAQTVANCYTALDLDVEVVPVLNKIDLPAADPENARGEIEDVIGVDASEAIL
                     CSAKTGLGVEEVLEAIVARVPPPKGEPDGPLKALIIDSWFDNYVGVVMLVRVVDGELK
                     PKDRILLMSNGAQYPCDQVGVFTPRSVSRDALRAGEVGFVIAGIKEIEAAKVGDTITL
                     ANKPASAPLPGFKEIKPQVFAGLYPVESSEYDQLRDSLEKLRLNDSSLQFEPEVSQAL
                     GFGFRCGFLGLLHMDIVQERLEREFDMDLITTAPTVVYEVVLNDGSTIHVENPAKLPE
                     VGKYQEIREPIITATIFMPQDYVGPVITLCNQKRGNQIDMRYHGRQVQLIYEMPMNEV
                     VMDFFDKLKSVSRGYASLDYDFKEYRTADLVKLDLMVGGEKVDALSVIVHRASAQYRG
                     RELAAKLRGLIPRQMFDVPVQAAIGAHIIARETIKALRKNVLAKCYGGDITRKKKLLE
                     KQKEGKKRMKQVGNVEIPQEAFLAVLRTDEGK"
BASE COUNT         1837 a         3973 c         4135 g         1920 t
ORIGIN      
        1 gcggtttcgc cggcggcggc tggctggaag tcgacaaatc cacccttcgt catcgccgct
       61 tccccaacgt gttcggcatc ggcgacatca acggcacgcc caagggcaag accgccgcga
      121 cggtcaagaa gagcaccccg ctggtggtgc agaacctcat cgacgtcatc gccggccgcg
      181 aaccctcgca gcgcttcgac ggctacacct cgtgcccgct gctggtgcgc gagggtgccg
      241 cgctgctgat cgagttcgac tacgagaacc gcctgattcc ctcgctgccg gcgatcgatc
      301 cgctgcagga cagctacttc gcctgggtga tgaagatccg cctgctcaag cccgcctaca
      361 tggcggtcgc caagggccgg gtataaggga gacgagacat gtacgagatc tggctgacgc
      421 tgaacatcct ctatgaactc ggcctgcaat acctgccggt ggtgatcggc accgcgctgc
      481 tgtggctggt gctgatggcg gtcgccgcgg cgcgcggtcg cgccggctgg ggcgcggcgc
      541 tcaagccggc gatcgcggta gcggtcgtgg tcaccgcgat caccttcttc atcacccccg
      601 gcatgacgca gtcgtccttc gccaacatgg gctactgggt ggactggggc aacctcctcc
      661 tctacgcggc cgccttcggc gcggtcggcg gcgcgctggc gtggccgctc gccgcgatga
      721 tgcgtcgcgc ctgaaccgct gacccttcgc cctgccacgg gcgtcatccg tggcggggcc
      781 tcacgcttcc acccgacctt gcaaggagcc tcaccatgaa acgcctgctg atcgccaccg
      841 ccctcggcat cgccagcctc gccgcgcaag cggccgacat cgccatctcg gcgcaggaca
      901 cctacgccaa gatccagagc aacgaaagga acgtgctctt catcgacgtg cgcgacccgg
      961 tcgagatcat gttcgtcggc ttcgcggacg cggtgcacgc caacgtgccc ttcatgatgg
     1021 tcgatcgcac gcaatggaac gcggagaaag gtgtcttccg cctctaccgc aaccccgact
     1081 tcatcaacca ggtcaagctg cagctcgcca ggcgcggcct gagcgccgat gcggagatca
     1141 tcaccatgtg ccgctcgggc agcgagcgcg gcgaaccgag cgccgccttc ctgcgcgaga
     1201 acggtttccc gaacgcccgc tacgtggtgg acggcttcca gggcagtgcg ctcaaggagg
     1261 ggccgcaggc cggcttccgt ctgaagaacg gctggcagaa cagcggcctg ccatggtcgg
     1321 cgaagatgaa cgcggacaag atgcaccgcg tcgatcgccc ctgagcctgg ccccgagcgc
     1381 cctcgccccg gcgcgcaaag cctccggaag gcgcgccggc tgcgctagac ttcggccccg
     1441 acgggcacct cgcccggccc cgagatcccc tggagaagcg catgagcctg ctggcccaac
     1501 tgaagaaaga ctcgatgctc gcacgcaagg ccgccgacgg catccgtgcg accctgctca
     1561 gcaccctgat cggcgaagca gagatggtgg gcaagaacgc cggcaaccgc gagagcaccg
     1621 acgacgaggt gcagcagacg atccgcaagt tcctcaagaa caaccaggag gcgctcgccg
     1681 tgatcaagga cgccgaccgc cgcaccgcgc tggaacagga gtctgccatc ctcgtcgcct
     1741 acctgccgcc gatggccagc gaggccgagg tgaaggcctt catcgccgac accgtggccg
     1801 gcctcgccga gcgctcgccc aagcagatgg gcgcggtgat gggcgcgctg aaggcgaagt
     1861 acggcagcgg cttcgacgcc aagcaggcca acgcctgggt gaaggaagcg ctgacaggtt
     1921 gacaagggcc actgcagcaa gcgttcgcgg cttccgccgc tcctgcaggg gcctgtacgg
     1981 cacggttttc cggcaggagc ggccgaagcc gcgaacggtc gtgcagccac gaccgcaacg
     2041 cgctcggggc aggaacgact caatcagcgc aacgcggcgt ggatctgctc cgcgagcttg
     2101 cggctgacac cctccacccg gcacagatcc tccaccgtcg cctcgcgcac gccgtccagc
     2161 ccgccgaagg cggcgagcag gttgcgtcgg cgtgaaggcc ccacaccggg aatgtcctcg
     2221 agcttcgacc ccacccgcgc cttgccgcgc ctggcgcggt ggccggtgat ggcgaagcgg
     2281 tgcgcctcgt cgcggatctc cacgatcagg tgcagcgccg ccgactcgcc gcccagggcc
     2341 agtccttcgc gcccatccgg gaagatcagc gtctccagcc ccgccttgcg gccctcgccc
     2401 ttggccacgc cgaccatcgc caccgcctcc aggccgacct cggcgaggat cgcgcgtgcg
     2461 gcactgacct ggcccttgcc gccgtcgatc aggatcaggt cggggcacac gccctccccg
     2521 gccgcgacct tgccgtagcg gcgctccagc gcctggcgca tggcggcgaa gtcgtcgccg
     2581 ccggtgatgc cggtgatgtt gtagcggcgg tactcggcgc gcttcatggc gcccgcctcg
     2641 cacaccacgc aggacgccac ggtggcctcg cccatggtgt ggctgatgtc gaagcactcg
     2701 atgcgctgcg gcgcctcgtc caggtcgagc gcgctgcgca aagcctccag gcgctgctcg
     2761 atgcggccgg tgtcgcgcgc gcgcgcctgg atggcgaggt gggcgttctt ctcggccatc
     2821 tccatccacg ccttctcggc cgcaaagcgc ggcgacacca cgccgggtgg gcgctcggtg
     2881 atctcggcga gcgtctcctt cacagcctcc ggcggcaggt tgaccaggat gcgcgccggg
     2941 atcgggtgct ggctgtagtg ctgctcaacg aaggcgagca ggctgtccat cgcgcccgac
     3001 accgccgcgc cgctggggaa ctgcgggcgg tcgccgaggt ggcggccgcc gcgcaccatg
     3061 gcgatgttca cacaggtgag gccgtcggcc tcgatcgcgg ccagcacatc gacgtcctcg
     3121 tccttgcggc tgtcgacgaa ctgcttgtgc agcacggcct gcagcacgcg cacctggtcg
     3181 cggcaggcgg cggcctcctc gaaggcgagg cgctcggcgg cggcctgcat ccggttcgtg
     3241 aggtcgtcga tgacctcgct cgcctggccg tcgaggaagc gggtggcgag cctgacgtcg
     3301 gcggcatagg cctcgggctc gatcagcccg acgcagggcg cggtgcaacg cttgatctgg
     3361 tgcagcaggc agggacgcga gcggttggcg aagacggtgt tctcgcaggt gcgcagctgg
     3421 aaggtcttct gcagcaggtg gatgctctcg cgcaccgccc aggcgttggg gaaggggccg
     3481 aagtagcgcg cgcccttggt gaaggcgccg cggtggtagg ccaggcgagg gtattcgtct
     3541 gcggagagct cgatgtaggg gtaggtcttg tcgtcgcgga agaggatgtt gtagcgcggc
     3601 gccaggctct tgatgaggtt gttctcgagg atcagggcct cggcctcgga gcgggtggcg
     3661 gtgatgtcca cgcgcagcac ctgcgccacc atcatggcga tgcgcgggct ggagacggtc
     3721 ttctggaagt agctggagac gcggcgcttg aggttcttgg ccttgccgac gtagagcacc
     3781 ctgtcgtcgg cgccgatcat gcgatagacg ccgggctcct cggtaagggt gcgcaggaag
     3841 ggcttggggt cgaaggcggg gggggacgtc gggtcggtca tcgaggaaca gccttggcac
     3901 gccggcgggt gggccgccgg gacggaatca tccttccttg cgcaggatct cggtgcgctg
     3961 ctcgccgatg gcggcggcgg tcatggtcgc tgcggtgctg gtgtcgtcgt ggacggtgcc
     4021 gacgcgctcg cgagcctgca ggtaggcggt gtggagctcg agcacgaaag ggtcggcgag
     4081 ccacgcgggc ggtgcgacgg ccggcgtgat cgcggcgagt cgggcgagat ggtcggcgtc
     4141 gggctcgggc gcccagcggt cgagcaactc ggcggccagg tcggggcggt tgcacaccag
     4201 cagcatgtcg cagcctgccg catacgcggc cttcgcccgg ccgacgatgt cgccggcgac
     4261 gcgggcacct tccatgttga ggtcgtcgct gaagatcacg cccctgaagc cgagccggcc
     4321 gcgtagcacg tccttcagcc agaagggtga gaagccggcg ggctggggct ccgcactcgg
     4381 gtcggccttc gggtagatga catgggcggg catgaccccg gcgagctggc ggccgagacg
     4441 gtggcggtag ggggcgatgt cctcgttcca cacggtgtcg aagtcgcgct catccaccgg
     4501 cacgtcgtga tgcgaatcgg cctcgacgaa accgtggccg gggaaatgct tgccgaccgc
     4561 gcccatcccc gcctccgcca tgccggcgac cagcgcctgg gcgagcgcgg cgatcacctg
     4621 cgggtcgcga tggaaggcgc ggttgccgat cgcgcggcag cagccgtagt cgaggtcgag
     4681 caccggcgtg aagctgagat cgacgccgtg cgcacgcagc tcggacgcca gcacgaagcc
     4741 ggtggcgcgc gcggcctcga gcgccgcgag gtgatcctgc tcccacagcg cgcccaggct
     4801 gcgcatcgac ggcaagcggg tgaagccgtc ggtgcggaag cgctgcaccc ggccgccctc
     4861 atggtcgacc gcgatgatca gcgccggatc gcgcagcgcg cggaggtcgg cggtgagcgc
     4921 gcgcagctgg tcggaatcgg tgtagttgcg cgcgaacagg atcaccccac cgaccagcgg
     4981 atcgagcagg cgctcgcgct cctcgtcggt cagggcggtg ccggcgacat cgatcatcac
     5041 ggggccgcgc gggcggcgga cgggtgcatt catgtgctgg ggatcccgga gctcacgctc
     5101 tttcgatcag ggcgaaggcg acgatgtgtt cgtcctcgtc gctgatgctg aggtgggcgc
     5161 gcagggcgtt gtcgcgcatg tgcgcggcga ggcgctcgtc gtagcggtat tcgggcttgc
     5221 cgcgcgcgtc gtgaacgacg gcgaccgcgt gcagggtggc cggcacggcg acgccggtgc
     5281 cgagcgcctt gccgaaggcc tccttggcgg cgaagcgctt ggcgaggaag cgcgccggat
     5341 cgcggtgggc gcgccaggcc tcgacctcgc ttgcggccag gatgcgcagg gcgaagcgct
     5401 cgccgtggcg ctcgagcgcc tcgcgcatgc gccgcagctg cacgagatcc gtgccgatgc
     5461 cgtggatcat gctcgtgcgc tcgcactcag gcgcgcccgc gcccctgcag gagcggcgga
     5521 agccgcgaat gctgcatccg acccgggcgg tggcatggac ccgggcgccg tgttcgcggc
     5581 ttccgccgct cctacaaggg cgcgctggcg ggctgagctg tcggcggctg cgagggggca
     5641 acggcgtggt gtgggcatcg cgcttcttca ggcctgctgc gccgcttcgc gcatcagccg
     5701 cttcatctcg gccaccgccg cgcgcaggcc gacgaagacc gcacggctga cgatcgaatg
     5761 tccgatgtgc agctcgcgaa taccgtgcag gcgggcgatc ggctcgacgt tgtaatagtt
     5821 gagcgcgtgg ccggcgttga agcgcatgcc caggcgccgc accagctctc cggccgtgcg
     5881 gatcttttcc agctcgccga gcaccgccgg cgcctcggcg tcgcgaccgg cggcatggaa
     5941 ggcgtgggcg taggggccgg tgtggatctc gcacacgcgc gcgccgatgc gtgccgcggc
     6001 ctcgatctgc gcgggctcgg catcgatgaa cacgctggtg acgatgccgg cgtcggccag
     6061 gcgtgcgatc acgtccttca ggcgcgcttc ctgagacagc acgtcgagcc cgccctcggt
     6121 ggtgatctcg tggcggccct cgggcaccag catggccatc tgcggcttcg tgcgacaggc
     6181 gatcgcgacc atctcgtcgg tggcggccat ctcgaggttg agcttcacct gggtgagctc
     6241 ggcgagccgg cgcacgtcct cgtcgccgat gtggcggcgg tcctcgcgca ggtggatggt
     6301 gatgccgtcg gcgccgccga ggtgggcctc gaccgcggcc cacaccggat cgggttccca
     6361 ggtgcggcgc gcctggcgca gcgtggcgac gtggtcgatg ttgacgccga gttcgatcat
     6421 cagagctcct gcagttcctt gagtacccgg cgcgactgca gcggctggcc gcccagggtg
     6481 tggttgatca gcatgcgcag cagctgcttg gactgggcca gcgtctccgc gcgtgagaag
     6541 tcgccggccg ccatgtcgag cagggtctgg cccgagagca gcggctgctc gccgagtgca
     6601 gcggggtcga gggaagcgcc ctcttcctcc aacacctcga gccttaccgg accgcgctcg
     6661 attatataaa ggtagcgccc ctcgggccgc accggctcgc cgctgtcgcc ctcatgcgcc
     6721 agcccggcct cgtagccgag atcctgcagc agggcgagct cgaagcggcg caggatgggc
     6781 gactcgggtg cgccgcggcc gagcgcgcgc accgcctcgg cgtaggcgtc gaagaggcgc
     6841 gcatgcgcgt cctcgcgcgc ggtcaggcgc accagcagtt cgttgaggta gtagccgcag
     6901 atcagcgcac gcccggtcaa cagcggctgg ccgccctgcc actcggcgcg taccagggtc
     6961 ttgacctcgc cgccgcccga ccagtccatc catagcggct ggaaggcgag cagcacgccg
     7021 cgcagctggg agtgagggcg gcgcgcgccc ttggcgacca gggcgacgcg gccgaactcg
     7081 cgcgcgaaga tctccacgat caggctggtc tcacgccagg gataggtgtg cagcacccag
     7141 gccggctgct gctcgatgcg ctgcttggct cccgccatcg cccggagtcc ggattattcg
     7201 tagccgaggc tcttcagcgc gcgctcgtcg tcggcccagc cgctcttgac cttcacccag
     7261 acctcgagga agaccttgcc gtcgaagagc ttctcgagct cgacgcgggc ctcgctggag
     7321 atgcgcttga gcttctcgcc gccctttccg atcaccatcg atttgtggcc gggcttgtcc
     7381 acgatcaccg cggcgtagat gcggcgcagg ttgccctcca cctcgaactt ctcgatctcg
     7441 accgcgatgc cgtagggcaa ctcgtcgccg agcaggcgga agagcttctc gcgcaggaac
     7501 tcggaggcca ggaagcgctc gctgcggtcg gtgatctcgt cttcctcgaa catcggcgtg
     7561 gcgaccggaa gcagcggcgt ggcggccttc accagctcgt ccacgttgcg ccccttctcg
     7621 gccgacagcg gcacgatctc ggtgaagtca cgcgcctcgc gcacctgggc gatgaagggg
     7681 agcaggcgcg ccttgtcctt cagctggtcg accttgttga tgaccaggat caccttcgag
     7741 gcctccggga tcaccgccag caccttgcga tcgtcctcgg tgaagcggcc cgcctcgatg
     7801 acgaagaaca ccaggtcgac gtcggccagc acctgcgaca ccgtgcggtt catcgaacgg
     7861 ttgagcgcgt tgcggtggtg ggtctggaag cccggcgtgt cgacgaacac gaactgcgcg
     7921 cctgcctcgg tgaggatgcc ggtgacgcgg tggcgggtgg tctgcgcctt gctggagacg
     7981 atgctgatct tctgcccgat caggcggttg agcagcgtcg acttgccgac gttggggcgg
     8041 ccgacgatgg cgacgaagcc ggcgcgaaag ccgccttcgc cagtgggctc atcgctggag
     8101 ggatcttgag gcacttcggt catttttttc tcaccgcggc gagcgcgagc tcggccgact
     8161 gttgttcggc gatgcgccgg ctcgggccac ggcccagcgt gcgtaccgcg agtttgggga
     8221 tttcgcaggc gacctcgaac tcctgcgcgt gggcttcgcc gacgatctcg accatggtgt
     8281 aggtcggcac cgcgatacgg cgcgcctgca gccactcctg cagcgccgtc ttggcgtcct
     8341 tgctcggctt gcccgggtcg acctcggcga tcaggggcgc gtagagccga tcgatgaccc
     8401 ccttcgcggc ctcgaagccg gcatccaggt aaaccgcggc gaacagcgcc tcgagcgcat
     8461 cggcgaggat ggacgggcgg cggctgccgc ccgacttgag ctcgccctcg cccaggcgca
     8521 aacagtcgcc gagctcgagc tcgagcgcga gccggtgcag cgtgtcctgg cgcaccagcg
     8581 aggcgcgcac ccgcgacagc tcgccctcgc gcagctcgcc gaagcgaccg aacagcgcga
     8641 tcgacaccac gcagtcgagg atggcatcgc cgaggaactc gaagcgctcg ttattgggct
     8701 ggccaaagct gcggtgcgtc agcgcctctt caaggaggcg ccggtcggca aaggcatggc
     8761 ccaggcgcgc ctgaagtcgg tccggcatca tcggatcagc gcgacgcgct gctcggatgc
     8821 aggtcgatcg acaggctgac gttggccagc agcggcacct tgcgggtgta ctcgacctcg
     8881 atcacggtcc ggggtccgga cttgtcgatg ttcaggtccg agccgctcac gctgtggatg
     8941 tcgtcgatct gtccgcgccg atcgaagccg cggcgcagct cgatcagact ggcgcccttg
     9001 tcggcctcgt cggcgagcac accgagaatg cgcttgatcg cgaagtactc gttgaacacc
     9061 ggcacggtgc ggaagccgac taccagcacg aaggctgcga tcaccccggc caccagcaca
     9121 ccgagcagtg tgagcccgcg ctgcgaatgc atcttcatcc ctgcctccat tcagtcgaag
     9181 ccgccgatcc gcttcatgtc gccgaagttg aaccagatga aaaaggcgcg gcccacgatg
     9241 ttctgctcgg ggacgaagcc ccacacacga ctgtcgctgc tggcgtcgcg attgtcgccg
     9301 agcacgaagt aatgacccgc gggaacggtg cagcgcaccc ctgcgtgcac gtaggtgcaa
     9361 tgctcgcggc cggggaagtt gagcacctgc ggcacatagg ccggcgcgtc acgctcgatc
     9421 agcaccgagt gctcgacctc gccgagcttc tcgacatatc tgggcgagta gtacaggcga
     9481 tccggatgca ggtagctgcc atcctcgcgg atcggcaccg cctcgccgtt gatgacgagg
     9541 cgcttgtcga tgtattcgac gcggtcgccg ggcaggccga ccacgcgctt gatgtagtcc
     9601 atcgacggat cggcagggta gcggaacacc atcacgtcgc cgcgcttggg atcgttcacc
     9661 tcgatgatct tctggttgat caccggcagg cggatgccgt aggtccactt gttgaccagg
     9721 atgaagtcgc ccaccagcag ggtcgggatc atcgagcccg acgggatctt gaagggctcg
     9781 accacgaagg agcgcaggcc gaacacgatc aggatcaccg ggaagaagct cgcgccgtac
     9841 tcgacccacc acgggtcggg cgtgccggcc gggcgcagct tgcgcgcatg gaagcggtcg
     9901 aggaaccaca gcacgccggt ggcgatcagc agcagcaaca ggatcagggc aaaattcatg
     9961 cggtttccgt cgtgggccag cccgcctggg gccggcgtcg atcacttgcc ttcgtcggtg
    10021 cgcagcacgg caaggaaggc ttcctgcggg atctcgacgt tgccgacctg cttcatgcgc
    10081 ttcttgcctt ccttctgctt ctcgagcagc ttcttcttgc gcgtgatgtc gccgccgtag
    10141 cacttggcga gcacgttctt gcgcaaggcc ttgatcgtct cgcgcgcgat gatgtgcgcg
    10201 ccgatcgccg cctgcaccgg cacgtcgaac atctggcgcg ggatcaggcc gcgcagcttg
    10261 gcggcgagtt cgcgcccgcg gtactgcgcg ctggcgcggt gcacgatcac cgacaaggca
    10321 tccaccttct cgccgccgac catgaggtcg agcttgacga ggtcggccgt gcggtactcc
    10381 ttgaaatcgt agtcgagcga ggcgtagccg cgcgacaccg acttgagctt gtcgaagaag
    10441 tccatcacga cctcgttcat cggcatctcg tagatcagct gcacctggcg gccgtggtag
    10501 cgcatgtcga tctggttgcc gcgcttctgg ttgcacagcg tgatcaccgg gccgacgtag
    10561 tcctgcggca tgaagatggt cgcggtgatg atcggctcgc ggatctcctg gtacttgccg
    10621 acctcgggca gcttggccgg gttctcgacg tggatcgtcg agccgtcgtt gagcaccacc
    10681 tcatacacca ccgtcggcgc ggtggtgatg aggtccatgt cgaactcgcg ctcgagtcgc
    10741 tcctgcacga tgtccatgtg cagcaggccg aggaagccgc agcggaagcc gaagcccaac
    10801 gcctgcgaaa cttccggctc gaactgcagc gaggagtcat tcaggcgcaa cttctcgagg
    10861 gagtcgcgca gttggtcgta ctcggaggac tccaccggat acaggccggc gaacacctgc
    10921 ggcttgatct ccttgaagcc aggcagcggc gcgctcgcgg gcttgttggc gagcgtgatg
    10981 gtgtcgccca ccttggccgc ctcgatctcc ttgatgccgg cgatgacgaa gccgacctcg
    11041 cccgcgcgca gggcatcccg gctgaccgag cggggcgtga acacacccac ctggtcgcac
    11101 ggatactgtg cgccgttcga catcagcagg atacggtcct tgggcttgag ctcgccatcg
    11161 accacgcgca ccagcatgac cacgccgacg tagttgtcga accaggagtc gatgatcagc
    11221 gccttcagcg gcccgtctgg ctcgcccttg ggcggcggca cgcgggcgac gatggcctcg
    11281 agcacctcct ccacgcccag gcccgtcttg gccgagcaca ggatggcctc ggaggcgtcg
    11341 acgccgatca catcctcgat ctcgccgcgc gcgttttccg ggtcggccgc aggcaggtcg
    11401 atcttgttga gcaccggcac cacctcgacg tcgaggtcga gcgcggtgta gcagttggcc
    11461 acggtctgcg cctcgacgcc ctgcgaggca tcgaccacca gcagcgcgcc ctcgcaggcg
    11521 gcgagcgagc gactgacctc gtaggagaag tcgacgtgtc cgggggtgtc gatgaggttg
    11581 aggttgtaga cctggccgtc cttcgccttg tagtgcaggg ccgcggtctg cgccttgatc
    11641 gtgatgccac gctcgcgctc gatgtccatc gagtcgagga cctgctcctc catctcgcgc
    11701 tcggacaggc cgccgcagaa gtggatgagt cggtcggcca gggtcgattt gccgtggtcg
    11761 atgtgggcga tgatggagaa gtttcggatg tgcttcattt gaaacgaaaa aggtgccttt
    11821 cagcacccgt ttcggaaagg attcggttgg tcgctggccg ggttc
//
LOCUS       DAOTIN010000099        11859 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_6428_length_11859_cov_8.553202, whole genome shotgun sequence.
ACCESSION   DAOTIN010000099 DAOTIN010000000
VERSION     DAOTIN010000099.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 11859)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 11859)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11859
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6428_length_11859_cov_8.553202"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1232)
                     /locus_tag="P5537_12935"
     CDS             complement(<1..1232)
                     /locus_tag="P5537_12935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HRV78989.1"
                     /translation="MSNEQQVRIYNPSEEMVKNAAVSGMDGYRALCKEAEDDYEGYWG
                     RRAKELLDWKEPFTQVLDQSNAPFFKWFADGKLNVSYNCLDRNVNNGLGDKVALIFEA
                     DGGEVIRITYKDLLARVSKFANALRGMGVKKGDRVIIYLPMSIEGVVAMQACARIGAT
                     HSIVFGGFSAQALRDRIEDAGAVAVITSDGQFRGGKALPLKPIADEALSLGGCDSVKN
                     VIVVKRTGADVAMVAGRDTWYHDAVANQSETCEPEWVEAEHPLFILYTSGSTGKPKGV
                     QHSSGGYLLQAVLSMKYTFDIKPNDVYWCTADIGWVTGHTYITYGPLACGATEIVFEG
                     VPTYPDAGRFWKMIQDHKVSIFYTAPTAIRSLIKAADNNPAVHPKQYDLSSLRILGSV
                     GEPINPAAWEWYYENVGGG"
     gene            1522..3054
                     /locus_tag="P5537_12940"
     CDS             1522..3054
                     /locus_tag="P5537_12940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004356434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HRV78990.1"
                     /translation="MTIIRQEDLIQSIADAFQYISYYHPLDYIQALGEAYAREESPAA
                     KDAIAQILTNSRMAAEGHRPICQDTGIAVVFLKVGMNVQWDAKMSVQEMIDEGVRRAY
                     NHPDNKLRASVLLDPAGKRQNSKDNTPAVVHYEIVAGDDVEVICAAKGGGSENKTKMV
                     MLNPSDSIVDWVLKTVPTMGAGWCPPGILGIGIGGTPEKAMLLAKESLMEPVNIHELR
                     EKAASGAALSRVEELRLELMDKVNALGIGAQGLGGLTTVLDVKIMDYPTHAASLPVAM
                     IPNCAATRHVHFHLDGSGPAHLPTPKLEDWPQVTWKADTNVATRVNLDTLTKEEVASW
                     KPGQILLLNGRMLTGRDAAHKRIADMLEKGEKLPVDFTNRVIYYVGPVDPVRDEVVGP
                     AGPTTATRMDKFTRMMLEKTGLISMIGKSERGPVAIEAIKDNQSAYLMAVGGAAYLVS
                     KAIKEAKVVGFADLGMEAIYEFTVQDMPVTVAVDAKGTSVHNTGPKEWQAKIGKIPVA
                     VA"
     gene            complement(3119..6814)
                     /locus_tag="P5537_12945"
     CDS             complement(3119..6814)
                     /locus_tag="P5537_12945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HRV78991.1"
                     /translation="MQAAPRRASAALAELEARVARQAQMLSVLSALQRGMLVGRSSSD
                     TFSAMLDHLLALTGSEYGFIGEVLHDEAGESFLRMHGLSDISWSPESRTLFERMRTGG
                     FEFHNLDTLFGAVVRTAAPVICNAPAGDPRGAGLPPGHPELRAFLGLPLFHGGHLIGM
                     VGLANAEQGYDQALIVELEPMLVTCASMIIALRTEEDRKTARRALEESERHFRELANS
                     KSALIWTSDAEGGCNYFNDTWLQFTGRTLEQSRGTGWAADLHPDDAEGCLNTWRKAFA
                     RREPFRMEYRLRHADGGFRWISDEGNPRRDPDGTFLGYIGYCYDITERKRGDLALDAL
                     AARYARLSGEGFYEAVCRHVVEALDLDIAFVGQLCADGAHVEVRAGWGDGGVIRPFRY
                     ALAESPCDGTVGRGACIYPRGVHERFPRDRELVRMGIDAYAGVPLFDREGGVLGLMVA
                     LRRKPFDDEAAVRTLLEIFDDRVAAELVRERAERVLTGRIAFERLVGRISSELILAAP
                     AELDGHLDQALGELGRFAEADRAYVFQVSEDGCQLDNTHEWCAEGIEPQIDKLQGLPF
                     DDSLLFLRTIKQLGIVDYPSVAALPAEAEADRVLLEAQSIRSVLGVPMVVDGQVRGII
                     GLDAVCRERSWTDEDKTLMTLVGNAFSGVIERKRAHDGLLASEARYRSVVESVREVIF
                     LLDGEGRWTFLNKAWADITGHPLEESLGRHFLAHVHADDREQHGEMVEQVLAGELESC
                     THAARYRCAGGGFRWLEMSARRALDAQGRVVGLSGTLTDITRQKEHESRLEYIAHYDA
                     LTGLPNRVLLSDRMQRGMAQARRRGQQLALAYIDLDGFKSINDTLGHQAGDQLLTVVA
                     ARMKAALREGDSISRLGGDEFVALLLDLPDVEACELLVRRLLCAVSQAVALAGQEVKV
                     SASVGLTLYPQAEEVDADQLLRQADLAMYQAKLAGKNRYHVFDTAHDRSQRGRHQTLA
                     AIRGGLRASEFQLLYQPKVNMRSGAVVGVEALIRWRHPRQGELEPATFLPAVADHPLA
                     VEIGDWVIEQALAQVAAWQRGGLFLPVSVNVGARHLQAADFMLRLQAALARHPELGPG
                     ALELEVLETSALESITQVTRIVEACAGIGVSFALDDFGTGYSSLAYLKRLPAARLKID
                     QLFVRGMVDDAEDLAILKAIMGLAHAFKREVVAEGVEEVEHGSLLLELGCEVAQGYGI
                     ARPMPAERIPAWAASWSPPAPWRLARA"
     gene            complement(7022..9388)
                     /gene="ppsA"
                     /locus_tag="P5537_12950"
     CDS             complement(7022..9388)
                     /gene="ppsA"
                     /locus_tag="P5537_12950"
                     /EC_number="2.7.9.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008986 - pyruvate, water dikinase
                     activity [Evidence IEA];
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate synthase"
                     /protein_id="HRV78992.1"
                     /translation="MTRYVIPFNELRMSDVEKVGGKNASLGEMISQLPSSVRVPGGFA
                     TTAEAYREFLAHDGLADRINAALDALDVDDVDALAKTGAQIRQWIVDLPFPAKLEAEI
                     KTAYEAITAEGEGSFAVRSSATAEDLPDASFAGQQETFLNIHGYENILHAMKEVFASL
                     YNDRAIAYRVHKNFAHADVALSAGVQRMVRSDSGASGVMFSIDTESGFDQVVFITASY
                     GLGETVVQGAVNPDEFYVHKPTLALDKPAIIRRNLGSKLIKMVFTDKAVAGKSVRTVD
                     VPEADRNRFSLTDADVLELARYAVIIEKHYGRPMDIEWGKDGVDGKLYILQARPETVK
                     SQDSGLVMEKYRLKQYGKALTHGRAIGQKIGAGVVRIVGDASEMNRVQAGDILVTDMT
                     DPNWEPVMKRASAIVTNRGGRTCHAAIIARELGIPAIVGCGNATDVLHEGESVTVSCA
                     EGDTGYVYRGKLEFEVITTDMGNLPEIPVKIMMNVGNPELAFEFAQIPNGGVGLARLE
                     FVINNMIGIHPKAILDIGQVPASLRDEINRRSRGYATPKQFFIEKLVEGVATIAAAFY
                     PKPVIVRMSDFKSNEYRKLLGGEIYEPEEENPMLGFRGASRYIAHSFRDCFEMEVAAM
                     KKVRNELGLTNVQIMIPFVRNLEEAAGVVDLLAEHGLKRGANDLKLIMMCEIPSNAIL
                     AEQFLQYFDGYSIGSNDLTQLTLGLDRDSGLVAHSFDERDPAVKQLLSMSIQAANKLG
                     KYVGICGQGPSDHPDLAEWLMDEGIQTISLNPDTVVDTWLKLAAHGKR"
     gene            9526..10359
                     /locus_tag="P5537_12955"
     CDS             9526..10359
                     /locus_tag="P5537_12955"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004356440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="HRV78993.1"
                     /translation="MNDIARRTVFFVSDGTGITAETLGHSLLAQFPEARFRQVRAPFI
                     DDIDKAIDCATQIREAAAEDGVRPIVFSTLVNQATVDALHKSDALFLDLFERFIGPLE
                     AELGQRSTHAVGRFHGIADSLNYKHRIEAINFAMAHDDGISSEGELAEADVILVGVSR
                     SGKTPTSLYLAMQFGVKAANYPLIPEDFERNKLPGELHKYRGKLFGLTIAPERLSQIR
                     QERRPNSRYASLENCRYEIDAAHKLMRRENIRCLDSTAKSIEEISATILQTIRVDRPG
                     F"
     gene            10466..11635
                     /locus_tag="P5537_12960"
     CDS             10466..11635
                     /locus_tag="P5537_12960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2863 family protein"
                     /protein_id="HRV78994.1"
                     /translation="MKRTRLKRRGGLGRTAEQLAWLAGGLAQSGSRIEDHYWETQLAR
                     LIDETLADNDEEVLNAALDHLFSADARAYDELADNIESRAECAAGSIAGHDVVLIAAP
                     VLAWSRYRIPATNIPAAVLANLRVHLQAHVLAKGARLSVADFLFSPDQLPQGYCATAE
                     FAKVICGAAVDNLDLHIDTEGMPETAQFLSDTRYLLAAVAVPRGAALFRWQEPDGTRD
                     GALEQWRAQGGACLTPLLPGCAVDLVLPDSYFAASRAADKDSRPYSVRASVAFLATTL
                     ETPAANLRAVVAPFWDRNLEEYRIGFTARGRDAVVHGVVWPLLGAEDETTDCVAQIET
                     VLRESGLTDVVSLEHHFPLEYCDDCGAPLYPSPEGEVVHAEMPEEQGVQAPRHLH"
     gene            11653..11760
                     /locus_tag="P5537_12965"
                     /pseudo
     CDS             11653..11760
                     /locus_tag="P5537_12965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298623.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase"
BASE COUNT         1939 a         4146 c         3923 g         1851 t
ORIGIN      
        1 ccgccgccga cgttctcgta gtaccactcc caggccgccg ggttgatcgg ctcgccgacc
       61 gagccgagga tgcgcagcga ggacaggtcg tactgcttcg gatgcacggc cgggttgttg
      121 tcggcggcct tgatcaacga gcggatcgcg gtcggcgcgg tgtagaagat gctgaccttg
      181 tggtcctgga tcatcttcca gaagcggccg gcgtccggat aggtcggcac gccttcgaac
      241 acgatctcgg tcgcgccgca ggcgagcgga ccgtaggtga tgtaggtgtg accggtgacc
      301 cagccgatgt cggcggtgca ccagtagacg tcgttcggct tgatgtcgaa ggtgtacttc
      361 atcgacagca cggcctgcag caggtagccg cccgaggagt gctgcacgcc cttcggcttg
      421 ccggtggagc ccgaggtgta gaggatgaac agcgggtgct cggcctcgac ccactccggc
      481 tcgcaggtct cggactggtt ggcgaccgcg tcgtggtacc aggtgtcgcg accggcgacc
      541 atggcgacgt cggcaccggt gcgcttgacg acgatgacgt tcttgaccga gtcgcagccg
      601 cccagcgaca gcgcctcgtc ggcgatcggc ttgagcggca gcgccttgcc gccgcggaac
      661 tggccgtcgg aggtgatcac ggccaccgcg ccggcgtcct cgatgcggtc gcgcagggcc
      721 tgggcggaga agccgccgaa cacgatcgag tgggtcgcgc cgatgcgggc gcaggcctgc
      781 atcgcgacca cgccttcgat cgacatcggc aggtagatga tgacgcgatc gcccttcttg
      841 acgcccatgc cgcgcagggc gttggcgaac ttgctgacgc gggcgagcag gtccttgtag
      901 gtgatgcgga tgacttcgcc gccgtcggct tcgaagatca gcgcgacctt gtcgccgagg
      961 ccgttattga cgttacggtc gaggcagttg taggagacgt tgagcttgcc gtctgcgaac
     1021 cacttgaaga aaggcgcgtt cgactggtcg aggacctggg tgaagggctc cttccagtcc
     1081 agcaactcct tggcgcggcg gccccagtaa ccctcgtagt cgtcctcggc ctccttgcac
     1141 agcgcgcgat aaccgtccat gccggacacc gctgcgttct tgaccatctc ttccgagggg
     1201 ttgtaaatgc ggacttgttg ctcgttggac atgctcacct ctcctcaact gttcaaatgg
     1261 ttgaagctac ccgttgcggg tgggctggtt gaacccagcc tttgatttgc ccgaacgccg
     1321 acgccccctt gcgggccctc cccgtccgga cactcggatg ccgttcgaaa cgccggcatt
     1381 agagaacagc tatcttacac aggacttaca ccgcctcgcc agcgacggcc ggcggggccg
     1441 gtggtagaat ccggcgccac tccgggcctc gcggcccggt cgcgtcattc tgcccccatg
     1501 tcattccgga gaccaagcgc catgacgatc attcgccagg aagacctcat ccagtcgatc
     1561 gcggatgcct tccagtacat cagctactac cacccgctcg actacatcca ggcgctcggc
     1621 gaggcctacg cgcgcgagga gagcccggcc gcgaaggacg cgatcgcgca gatcctgacc
     1681 aactcgcgca tggccgccga aggccaccgc ccgatctgcc aggataccgg catcgcggtg
     1741 gtctttctca aggtcggcat gaacgtgcag tgggacgcca agatgagcgt ccaggagatg
     1801 atcgacgagg gcgtgcgccg cgcctacaac caccccgaca acaagctgcg cgcctcggtg
     1861 ctgctcgacc cggccggcaa acgccagaac agcaaggaca acaccccggc ggtggtgcac
     1921 tacgagatcg tcgcgggcga cgacgtcgag gtcatctgcg cggccaaggg cggcggctcc
     1981 gagaacaaga ccaagatggt catgctcaac ccctccgact cgatcgtcga ctgggtgctc
     2041 aagaccgtgc cgaccatggg cgcgggctgg tgtccgccgg gcatcctcgg catcggcatc
     2101 ggcggcaccc cggagaaggc gatgctgctg gccaaggaat cgctgatgga gcccgtcaac
     2161 atccacgagc tgcgcgagaa ggccgcctcc ggcgccgcac tcagccgcgt cgaggagctc
     2221 cgcctcgagc tcatggacaa ggtcaacgcg ctcggcatcg gcgcccaggg cctgggcggc
     2281 ctcaccaccg tgctcgacgt caagatcatg gactatccga cccacgccgc ctcgctgccg
     2341 gtggcgatga tccccaactg cgccgccacc cgccacgtgc acttccacct cgacggctcg
     2401 ggccccgcgc acctgccgac ccctaagctc gaggactggc cgcaggtcac ctggaaggcc
     2461 gacaccaacg tcgccacccg cgtgaacctc gacaccctca ccaaggaaga ggtcgcctcc
     2521 tggaagccgg gccagatcct gctcctcaac ggcaggatgc tcaccggccg cgacgccgcg
     2581 cacaagcgca tcgccgacat gctggagaag ggcgagaagc tgccggtcga cttcaccaac
     2641 cgcgtgatct actacgtcgg cccggtcgac ccggtgcgcg acgaggtcgt cggtcccgcc
     2701 ggccccacca ccgccacgcg catggacaag ttcacccgca tgatgctgga gaagaccggc
     2761 ctcatctcga tgatcggcaa gtccgagcgc ggtccggtgg ccatcgaggc gatcaaggac
     2821 aaccagtcgg cctacctgat ggcggtcggg ggcgcagcct atctggtgtc gaaggcgatc
     2881 aaggaagcca aggtcgtcgg cttcgccgac ctcggcatgg aagcgatcta cgaattcacc
     2941 gtgcaggaca tgccggtgac ggtcgcggtc gacgccaagg gcaccagcgt gcacaacacc
     3001 gggccgaagg aatggcaggc gaagatcggc aagatcccgg tcgccgtcgc ctgagcccgc
     3061 tcccatcctg aagcaccctg cccgctccct cgcacggggg ggcgggcgcg gcgccggctc
     3121 aggcccgcgc caggcgccac ggcgcggggg gcgaccagct cgccgcccag gcggggatcc
     3181 tctccgccgg catcggccgc gcgatcccgt agccctgcgc cacctcgcaa ccgagctcca
     3241 gcagcaggct gccatgctcc acctcttcca cgccctcggc gaccacctcg cgcttgaagg
     3301 catgggcgag ccccatgatc gccttcagga tggcgagatc ctcggcgtca tccaccatcc
     3361 cgcgcacgaa cagctggtcg atcttgaggc gcgccgccgg tagccgcttg agatacgcga
     3421 gcgaggaata ccccgtcccg aagtcgtcga gcgcgaagga cacgccgatg cctgcgcagg
     3481 cctcgacgat gcgcgtgacc tgggtgatgc tctccagcgc gctggtctcc agcacctcca
     3541 gttccagtgc acccggtccc agttcggggt gacgcgcgag cgccgcctgc agccgcagca
     3601 tgaaatccgc cgcctgcaga tgacgcgcgc ccacgttcac gctcaccggc aggaacaagc
     3661 ccccacgctg ccaggcggca acctgcgcga gcgcctgctc gatgacccag tcgccgatct
     3721 cgaccgcgag cgggtgatcg gccaccgccg gcaggaaggt cgccggctcg agctcgccct
     3781 ggcgcggatg gcgccagcgg atcagcgcct cgacccctac caccgcgccg ctgcgcatgt
     3841 tcaccttggg ctggtacagg agctggaact cgctcgcgcg caagcccccg cggatcgccg
     3901 ccagggtctg gtggcggccg cgctgggagc gatcgtgcgc ggtgtcgaag acgtggtagc
     3961 ggttcttgcc ggcaagcttg gcctggtaca tcgcgaggtc ggcctggcgc agcagctggt
     4021 cggcatcgac ctcctcagcc tgggggtaaa gggtgagccc gacgcttgcc gagaccttca
     4081 cctcctgccc cgcgagcgca accgcctgcg acaccgcgca gagcaggcgg cgcacgagca
     4141 attcacaggc ctcgacgtcg ggcagatcga gcagcagcgc gacgaactcg tcgcccccca
     4201 ggcgcgagat gctgtcgccc tcgcgcagcg ccgccttcat gcgcgccgcc accaccgtga
     4261 gcaactggtc gccagcctgg tggccgaggg tgtcgttgat cgacttgaag ccgtcgaggt
     4321 cgatgtaggc gagcgcgagc tgctggccgc gcctgcgcgc ctgcgccatc ccccgctgca
     4381 tgcggtcgct gagcaggacg cggttgggca gcccggtcag tgcatcgtag tgcgcgatgt
     4441 actcgaggcg ggactcgtgc tccttctgcc gggtgatgtc ggtcagcgtg ccggagagcc
     4501 ccacgacccg gccctgcgca tcgagcgcac gccgcgcgct catctccagc cagcgaaagc
     4561 cgccgccggc gcagcggtag cgcgcggcgt gggtgcagga ctcgagttcg cccgcgagca
     4621 cctgctcgac catctcgccg tgctgctcgc gatcgtcggc atgcacgtgg gcgagaaaat
     4681 ggcggccgag gctctcctcc aggggatggc cggtgatgtc ggcccaggcc ttgttgagga
     4741 aggtccagcg cccctccccg tcgagtagga agatcacctc gcgcacgctc tccaccaccg
     4801 accggtagcg tgcctcgctc gccaacagcc cgtcgtgcgc gcgcttgcgc tcgatgaccc
     4861 cgctgaaggc gttgcccacc agggtcatca gggtcttgtc ctcgtcggtc caggagcgct
     4921 cgcggcacac cgcgtcgagc cctatgatgc cgcgcacctg cccgtccacc accatgggca
     4981 ccccgagcac cgaccggatc gactgcgcct cgagcagcac gcggtcggcc tcggcctcgg
     5041 ccggcagcgc ggcgacgctg gggtagtcga cgatcccgag ctgcttgatg gtgcgcagga
     5101 agagcagcga gtcgtcgaag ggcaggccct ggagcttgtc gatctgcggc tcgatgccct
     5161 cggcgcacca ctcgtgggtg ttgtcgagct ggcagccgtc ctcggagacc tggaacacat
     5221 aggcgcgatc ggcctcggcg aagcggccga gttcgccgag ggcctggtcg aggtgcccgt
     5281 ccagctcggc aggcgcggcc aggatcagct cggacgagat ccgccccacc aggcgctcga
     5341 acgcgatccg cccggtcagc acgcgctcgg cgcgctcgcg caccagctcg gccgccaccc
     5401 ggtcgtcgaa gatctcgagc agggtgcgca ctgccgcctc gtcgtcgaaa ggcttgcggc
     5461 gcagcgccac catcaggccg agtacgcccc cctcgcggtc gaacagcggc acgccggcat
     5521 aggcgtcgat gcccatgcgc acgagttcgc ggtcgcgcgg aaagcgttca tgcaccccac
     5581 gcgggtagat gcacgccccc cgcccgaccg tgccgtcgca gggggactcg gcgagcgcgt
     5641 agcggaacgg acgtatgacg ccgccgtcgc cccagcccgc gcgcacctcg acgtgcgccc
     5701 catcggcgca gagctggccg acgaaggcga tatccagatc gagcgcctcg acgacgtgcc
     5761 ggcacaccgc ctcgtagaag ccctcgcccg acagccgcgc atagcgcgcc gcgagcgcat
     5821 cgagcgcgag atcgccgcgc ttgcgctcgg tgatgtcgta gcaatagccg atgtagccga
     5881 ggaaggtgcc gtcggggtcg cggcgcggat tgccctcgtc cgagatccac cggaagccgc
     5941 cgtcggcatg gcgcaggcgg tattccatcc ggaacggctc ccggcgcgcg aaggccttcc
     6001 tccaggtgtt caggcaaccc tcggcgtcgt ccggatgcaa gtcggccgcc cagcccgtgc
     6061 cccgggactg ctccagcgtg cggccggtga actgcagcca ggtgtcgttg aagtagttgc
     6121 acccgccctc ggcatccgat gtccagatca gcgccgactt gctgttggcg agctcgcgga
     6181 agtggcgctc gctctcttcc agggcgcgac gcgcggtctt gcggtcctcc tcggtgcgca
     6241 gcgcgatgat catgctcgcg caggtgacca gcatgggctc gagctcgacg atcaaggcct
     6301 ggtcgtagcc ctgctccgca ttcgccagcc cgaccatgcc gatcaaatgc ccgccgtgga
     6361 acagcggcag gccgagaaag gcccgcagtt cggggtgtcc gggcggcagc cccgcgccgc
     6421 ggggatcgcc ggcgggcgca ttgcagatca ccggggcggc ggtccgcacg accgcaccga
     6481 acaaggtgtc gaggttgtgg aactcgaagc caccggtacg catgcgctcg aagagggtgc
     6541 gcgactccgg actccacgag atgtcgctga gcccgtgcat gcgcaggaag gactccccgg
     6601 cttcatcgtg caggacctcg ccgatgaagc cgtactcgct gccggtcagc gcgaggaggt
     6661 ggtcgagcat cgccgagaag gtgtcggagg aggagcgccc caccagcatg ccgcgctgca
     6721 gggcagacag caccgacagc atctgcgcct gccgtgcaac gcgcgcctcc agctccgcga
     6781 gcgcagccga ggcgcgccgt ggcgccgctt gcaccccctc ctgccctggc tcgacgggca
     6841 cgtcacccgg caactcgttc cccaagcccg acatccgatc ccctcgaatc cgcaagcaag
     6901 acaagcgcgc atcttagcgg gaagcctttc ccggcggcat gactgcaacg cctggatgca
     6961 taaaaaaggc gccgaccctg ccggtcggcg ccctcgatgc gacagcccgc gtgggcgagg
     7021 ttcagcgctt gccgtgcgcg gcgagcttga gccaggtatc gaccaccgtg tcggggttca
     7081 gcgagatggt ctggatgccc tcgtccatca gccactcggc caggtcgggg tgatccgacg
     7141 ggccctggcc gcagatgccc acgtacttgc cgagcttgtt cgcggcctgg atggacatcg
     7201 acagcagctg cttgaccgcc ggatcgcgct cgtcgaagga atgcgccacc agccccgagt
     7261 cgcggtccag gcccagggtg agctgggtga ggtcgttcga gccgatcgag tagccgtcga
     7321 agtactgcag gaactgctcg gccaggatgg cgttggacgg gatctcgcac atcatgatca
     7381 gcttgagatc gttggcgcca cgcttgaggc cgtgctcggc gagcaggtcc accaccccgg
     7441 cggcctcttc gaggttgcgc acgaagggga tcatgatctg cacgttggtg aggccgagct
     7501 cgttgcgcac cttcttcatc gccgccactt ccatctcgaa gcagtcgcgg aagctgtgcg
     7561 cgatgtagcg cgaggcgcca cggaagccga gcatcgggtt ctcttcctcc ggctcgtaga
     7621 tctcgccgcc gagcagcttg cggtactcgt tcgacttgaa gtcggacatg cgcacgatca
     7681 cgggcttcgg gtagaaggcc gcggcgatgg tggccacgcc ctcgaccagc ttctcgatga
     7741 agaactgctt gggcgtcgcg tagccgcgcg agcggcggtt gatctcgtcg cgcaggctgg
     7801 ccggcacctg gccgatgtcg aggatggcct tggggtggat gccgatcatg ttgttgatga
     7861 cgaactccag gcgcgccagg ccgacgccgc cgttggggat ctgcgcgaac tcgaaggcga
     7921 gctcggggtt gcccacgttc atcatgatct tcaccgggat ctcgggcagg ttgcccatgt
     7981 cggtggtgat gacctcgaac tccagcttgc cgcggtacac gtagccggtg tcgccctcgg
     8041 cgcaggacac ggtgaccgac tcgccctcgt gcagcacgtc ggtggcattg ccgcagccga
     8101 cgatggccgg gatgccgagt tcgcgcgcga tgatcgcggc gtggcaggtg cggccgccgc
     8161 ggttggtcac gatcgcgctg gcgcgcttca tcaccggctc ccagttgggg tcggtcatgt
     8221 cggtgacgag gatgtcgccg gcctgcacgc ggttcatctc ggaggcgtcg ccgacgatgc
     8281 ggaccacgcc ggcgccgatc ttctggccga tcgcgcggcc gtgggtgagc gccttgccgt
     8341 actgcttgag gcggtacttc tccatcacca ggccggagtc ctggctcttc accgtctcgg
     8401 ggcgggcctg caggatgtag agcttgccat cgacaccgtc cttgccccac tcgatgtcca
     8461 tcgggcggcc gtagtgcttc tcgatgatca ccgcgtagcg ggcgagttcg agcacgtcgg
     8521 cgtcggtcag cgagaagcgg ttgcggtcgg cctcgggcac atcgaccgta cgcaccgact
     8581 tgccggccac ggccttgtcg gtgaacacca tcttgatgag cttggagccg aggttgcggc
     8641 ggatgatcgc cggcttgtcg agcgccaggg tgggcttgtg gacgtagaac tcgtccgggt
     8701 tcaccgcgcc ctgcaccacg gtctcgccga ggccgtagga ggcggtgatg aacaccacct
     8761 ggtcgaagcc cgactcggtg tcgatcgaga acatcacgcc cgaggcgccc gagtccgagc
     8821 gcaccatgcg ctgcacgccg gccgacagcg cgacgtcggc gtgggcgaag ttcttgtgca
     8881 cgcggtaggc gatcgcgcgg tcgttgtaca gcgacgcgaa cacctccttc atcgcgtgca
     8941 ggatgttctc gtagccgtgg atgttgagga aggtctcctg ctggccggcg aaggaggcgt
     9001 ccggcaggtc ctcggcggtg gccgacgagc gcaccgcgaa gctgccctcg ccctcggcgg
     9061 tgatggcctc gtaggcggtc ttgatctcgg cctcgagctt ggccgggaag ggcaggtcca
     9121 cgatccactg gcggatctgc gcgccggtct tggcgagcgc atcgacgtca tccacgtcga
     9181 gcgcgtcgag cgcggcgttg atgcggtcgg ccaggccgtc gtgggcgagg aactcgcgat
     9241 aggcctcggc ggtggttgcg aagccgcccg ggacgcggac gctggaaggc agctggctga
     9301 tcatctcgcc gagcgaggcg ttcttgccgc cgaccttctc gacgtcggac atgcgcagtt
     9361 cgttgaaggg aatcacgtag cgtgtcatgg gtggcttccg caaatgttgg ggagaaagca
     9421 gaatatcgcg aacggcagtg tacgattttt tgtgctgtgc cgcatcacag ggtttgcccc
     9481 aatacacgcc ccgcctcccc ggtcggggcc gcaaggtccg aaatcatgaa cgacatcgcc
     9541 cgccgcaccg tcttcttcgt ctccgacggc accggcatca ccgccgaaac ccttggccac
     9601 agcctgttgg cgcagtttcc ggaggcgcgc ttccggcagg tgcgcgcgcc tttcatcgac
     9661 gacatcgaca aggcgatcga ctgcgcgacg cagatccgcg aggccgcagc cgaggacggc
     9721 gtgcgcccga tcgtgttcag cacgctggtc aatcaggcca cggttgatgc actgcacaaa
     9781 tccgatgcgc tcttcctcga cctcttcgag cgcttcatcg gaccgctcga ggccgagctc
     9841 ggccagcgct ccacccatgc cgtgggtcgc ttccacggca tcgccgacag cctcaactac
     9901 aagcaccgca tcgaggcgat caacttcgcc atggcgcacg acgacggcat ctccagcgag
     9961 ggcgagctcg ccgaggccga cgtgatcctg gtcggcgtgt cgcgctcggg caagactccc
    10021 accagcctat acctggccat gcaattcggc gtcaaggcgg ccaactatcc gctgatcccc
    10081 gaggacttcg agcgcaacaa gctgcccggc gagctgcaca agtaccgcgg caagctcttc
    10141 ggcctcacca tcgcccccga gcgcctgtcg cagatccgcc aagaacgccg ccccaacagc
    10201 cgctacgcct cgctggaaaa ctgccgctac gagatcgacg ccgcgcacaa gctcatgcgc
    10261 cgcgagaaca tccgctgcct cgactccacg gcaaagtcga tcgaggagat ctccgccacc
    10321 atcctgcaga ccatccgggt cgatcgcccg ggtttctgag cgcacggcgg gtgcttcgac
    10381 cggcgttttc ctgcggcatt ggtagaatgc ggggtcatgg gtgtcgccca agccggcacc
    10441 ccgaacagcg caacaggaac ccgacatgaa aagaacgcgc ctcaagcgcc gcggcggcct
    10501 cggccgcact gccgaacaac tcgcctggct cgccggcggg ctggcccagt ccggcagccg
    10561 gatcgaggac cactactggg agacgcagct cgccaggctg atcgacgaga ccctggccga
    10621 caacgacgag gaagtgctca acgccgcgct cgaccatctc ttcagtgccg acgctcgcgc
    10681 ctacgacgag ctcgccgaca acatcgagtc gcgtgccgaa tgtgccgccg gcagcatcgc
    10741 cgggcacgac gtcgtgctga tcgctgcacc ggtgctggca tggtcgcgct accgcatccc
    10801 ggccaccaac atccccgccg cggtgctcgc caacctgcgc gtgcacctgc aggcccacgt
    10861 gctcgccaag ggcgccaggc tgtcggtggc cgacttcctc ttcagccccg accagctccc
    10921 gcagggctac tgcgccaccg cggagttcgc caaggtgatc tgcggcgcgg cggtcgacaa
    10981 cctcgacctg cacatcgaca ccgagggcat gcccgagacc gcgcagttcc tctccgacac
    11041 ccgctacctg ctcgccgcgg tggcggtgcc gcgcggtgcc gcgctgttcc gctggcagga
    11101 gcccgacggc acgcgcgacg gtgcgctcga gcaatggcgt gcccagggag gcgcctgcct
    11161 caccccgctg ctgcccggct gcgcggtcga cctcgtgctg cccgactcct acttcgccgc
    11221 cagccgggcc gccgacaagg acagccgccc ctactcggtg cgtgcatcgg tcgccttcct
    11281 cgccaccacg ctggagacgc ccgccgccaa cctgcgcgcg gtggtcgccc cgttctggga
    11341 tcgcaacctc gaggaatacc gcatcggctt caccgcgcgg ggtcgcgacg cggtggtgca
    11401 cggcgtggtg tggccgctgc tcggcgccga ggacgagacc accgactgcg tcgcgcagat
    11461 cgaaaccgta ttgcgcgaat ccggtctcac cgacgtcgtg tccctcgagc accacttccc
    11521 gctcgagtac tgcgacgact gcggcgcccc gctctacccc tcccccgagg gcgaggtcgt
    11581 gcatgccgag atgcccgagg agcagggtgt gcaggcgccg cgccatctcc actgatccgc
    11641 cacgaggtag ccatggcccg cgaagtcgac aaacccgacg ccgaatggcg tcggcagctc
    11701 tccgacctgc agtaccgcgt cacccgcgaa aagggcaccg agcgcgcgtt caccggcgag
    11761 tgttgccggc tccctgattc cgcacaaatc tggcgtcgtt aaacggcgtc gttaaacggc
    11821 gtcgtcgagt gggcgccggc ggcgccgtaa acggcacga
//
LOCUS       DAOTIN010000100        11843 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_6434_length_11843_cov_9.214880, whole genome shotgun sequence.
ACCESSION   DAOTIN010000100 DAOTIN010000000
VERSION     DAOTIN010000100.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 11843)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 11843)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11843
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6434_length_11843_cov_9.214880"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            185..1132
                     /locus_tag="P5537_12970"
     CDS             185..1132
                     /locus_tag="P5537_12970"
                     /inference="COORDINATES: protein motif:HMM:NF025638.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4365 domain-containing protein"
                     /protein_id="HRV78995.1"
                     /translation="MTKPQTERLGVSALDYFFSKNGWLFREQTTHDYGIDAHVEIVKN
                     ERPTGRLIALQIKAGLSFFQEEADSAYVFRTDDKHISYWLEHSMPVVLVLYNPDTEQA
                     HWQHVARDTVETTGKGWKLSVPKISLFEEPEKFLKALAALTQPEPYIRRLNRLRIDRH
                     WMELIDRGYEVRVEFSDWVNKSLPRYQVTISTDNEKESWPTLYAPGLGIEGMLHHFFP
                     WADFSLDMDAHQQAAYGAWESECYAGRDSETGRVYYFMSFSEWYTPPAEDIVPISEDG
                     ETASYSLLLTLNDFGKSFLIVDDYLAEPDAPETKGFTLE"
     gene            1949..2713
                     /locus_tag="P5537_12975"
     CDS             1949..2713
                     /locus_tag="P5537_12975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase-related protein"
                     /protein_id="HRV78996.1"
                     /translation="MTSIAVDCVDGVGHLQLNRANALNALDLQFCTEIDDALLALDAR
                     EEVRAILISTSLKHFCAGADIREMLDMSAEQASATGFIGCVSAPPRLRKPLIVAVRGL
                     AAGGGCELVEMCDIVLAAASARFCHPEITLGAMPGAGGTQRLARVVGKHVALDLLLTG
                     RALSADEALSAGLVSRVLPDEELEAAAMSVARLVASYSSPVACRIKAAVNGAQVGLDA
                     GLAMERALFHACFSEHDFREGLAAFTEKRKPRFEHR"
     gene            2845..4263
                     /gene="yegQ"
                     /locus_tag="P5537_12980"
     CDS             2845..4263
                     /gene="yegQ"
                     /locus_tag="P5537_12980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004373741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 5-hydroxyuridine modification protein YegQ"
                     /protein_id="HRV78997.1"
                     /translation="MPASPPAPRRPELLAPAGSLDMMRTAFAYGADAVYAGQPRYSLR
                     VRNNSFGQLDTLAAGMAEAHAAGKLFYLVANIYPHNAKLRTFEEDMAPVVAMRPDALI
                     MADPGLILMVRERWPELPIHLSVQANTTNHASVRFWQSVGVKRIILSRELSLDEVAEI
                     RDACPDMELEVFVHGALCIAYSGRCLLSGYFNHRDPNQGSCTNSCRWDYKLHEAADNA
                     AGDVQACGGAPIGNPKDAGAVGTATRSALDTAQGLALGGGPRHLGGSKVWLLEEGTRP
                     GELMPIEEDEHGTYILNSKDLRAIEHVQRLVEIGVDSLKIEGRTKSPYYVARAAQGYR
                     RAIDDAVAGRPFDPRLLGELEGLASRGYTDGFYQRHSTPQHQNYLRGHSESGRSLLVG
                     EVVGFDAARGLAEVEVKNGFGVGDRLEFVQPDGNAEAVLARLFSATGETLERVPGSGR
                     RVWLALPAEADPARPCFVARFL"
     gene            4419..5087
                     /locus_tag="P5537_12985"
     CDS             4419..5087
                     /locus_tag="P5537_12985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004316751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family oxidoreductase"
                     /protein_id="HRV78998.1"
                     /translation="MILNIDLVSDFVCPWCFLGAVRLDRALAELRAARPDIEPRINWL
                     PFFLNPDTPPEGEPYRAFLEGKFGGPVKAEAVLDQVREAAAGDGLQYAFERIATRPNT
                     LAAHRLLYRAQAHGHKPERVRALAHALFAAHFQEGRDIGDLDTLADLAAACGDRRDVV
                     REWLESGADADKVQRMAAGLRRQGIDGVPFFILDRRLSLSGAQSAAVIGAALLQALET
                     GKPS"
     gene            5437..6231
                     /locus_tag="P5537_12990"
     CDS             5437..6231
                     /locus_tag="P5537_12990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004373734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HRV78999.1"
                     /translation="MHDTLVLADTDLRALAEARVLLERPSLAARLSSFVGSPLEKGMA
                     RLPASWRERIGGLAHDALMKAMDAAAKTLQPTAQPASPRLHKLLGSVSGAGGGAFGVA
                     GLTVEIPLSTVLIMRSILDIARGEGEDIGGTQARLAALEVFALGGNASGDDAAEAGYY
                     AVRAALATTVSEAARHFAQKGLSGEGAPALARLITMVAARYKVQLTQKAAGMLVPGIG
                     AAAGATINLMFMDHFQSVSRGHFTVRRLERRYGEAAVRAAWQTLGR"
     assembly_gap    6373..6472
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(6762..9338)
                     /locus_tag="P5537_12995"
     CDS             complement(6762..9338)
                     /locus_tag="P5537_12995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004373731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HRV79000.1"
                     /translation="MNRPESGFLLNEEAFSMPRTDEIRVGEIIGRNLLECAPEEPLHE
                     AARRMSERRVSSILVVEDDRVVGIWTERDALRVNFDDPATFALPVRAVMSSPVRAVSV
                     ATPLHELTVRFREEHVRHYVVEDDAGRRVGIVSQTDVVLNQGIEHYLKLRRVDALVKG
                     GLHALPAAAGLGDATRRMREGGVDAVVVDYGAPAASTPEGRYGILTERDVTRLVAERA
                     PDRALGELASRPLVTCRADNSLYRVRMLLVERQIRHIGVLDAEGGLVDLVSFKDILSG
                     MELAYVHELHDALRARDLALSASQRDLYLAEKVIESSLEGVMVTDAHARILSVNPAFT
                     RMTGYAPEEVVGLNPSVLNSGRQSPAFYARMWDGLLRDGHWQGEVWNRRKTGEVYPQL
                     LHITAIRDGEGVLTHYAALFTDISRLKETEARIRDLAYYDPLTGLPNRRLLDDRLQVE
                     LAHAARLRCRLAVMFVDLDRFKRINDSLGHTVGDKLLVEIAARLRVSLREDDTVARMG
                     GDEFLVVLNNLSGPDEAATMARRLVAELRRPVNVEGRELVVTTSVGVAVYPDDSRDAD
                     TLVKHADVAMYRAKDEGRNSFQLFEPAMNARSLERLALETALHRALPRDELQLYFQPV
                     MGAEGGELVAVEALLRWRHPDLGLVSPADFIPLAEDTGLIVPIGEWVLRSACEHHRRW
                     CEAGGGPLHMMVNISARQFREEGFAAMVASVLAETGMTPGDLTLELTESMLMDDTDRA
                     LARLDHLRALGVCLAIDDFGTGYSSLAYLKRFPIDELKIDRLFVRGIDRNTRDAALVS
                     AIVSLGHSLGLRVVAEGVETAAHLNVLRRQGCDLAQGFHFNPPLPWDEFVAAYPPAGA
                     TA"
     gene            9501..10697
                     /locus_tag="P5537_13000"
     CDS             9501..10697
                     /locus_tag="P5537_13000"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004316754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HRV79001.1"
                     /translation="MLRVLMISDVFFPRVNGVSTSIATFRRALAEQGVEVRLIAPRYA
                     GEAAEPGIVRIPGRRLPLDPEDRLVDARAMHAAARLEAAASDLVHIQTPFLAHRAGLR
                     AARAEGRPVLLTYHTFFEEYLHHYLPFLPAGVLRGLARRVSRTQCNAVDAVVVPSTAM
                     HERLTGYGVRSPMEILPTGIPLQDFAGGDGPHFRRLYDIPEDAPMALYIGRVAHEKNI
                     GFLLEVAARLKARRPDFVLVVAGEGPASARLQRQALAAGLDNTVRFVGYLERRKRLPD
                     CYAAADVFVFASRTETQGLVLLEAMAAGLPVVALSAMGTTDILGPERGARIAPDDPDG
                     FAAVVVGVLADPRLRRRLAAEARDYAAEWADGVMAGRLAALYRRLLAAPQAAQSQNAS
                     RIAATR"
     gene            10778..10981
                     /locus_tag="P5537_13005"
     CDS             10778..10981
                     /locus_tag="P5537_13005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004316756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HRV79002.1"
                     /translation="MNTTTLTITGMRDEECLRLVTNAIQDLPGIGYLEISLATGAATI
                     EHGAFVAESDIHQAIEDAGFGVR"
     gene            11065..>11843
                     /locus_tag="P5537_13010"
     CDS             11065..>11843
                     /locus_tag="P5537_13010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HRV79003.1"
                     /translation="MTPSLHSFPGGLAFVDIETTGGPAQRESITEVGIVQVDEDGVRE
                     WSTLVRPESRIPETIQRLTGIDDDMVADAPRFADIADEVFDRLDGRLFVAHNARFDHG
                     HLRAAFRRAGLDMRPQVLCTVKLSRRLFPDHRRHGLDHLIERHGLVVADRHRALGDAQ
                     LLWQFWQKIHERFPPGHIEAMVRELVGHPSLPPHLDPEQVAELPDTPGVYLFYGERDG
                     GTEGGTDSSALPLYIGKSTRLRSRVLSHFAADHTSDRELSL"
BASE COUNT         1892 a         4104 c         3884 g         1863 t
ORIGIN      
        1 tcagaagcct taaagcagga ctagccctga tgcctgcaat gacgtctaac cccctggtaa
       61 gcgcgtcctc tttgtcgctg atttttcccg gcgccttata tccgctatta cacagctcgg
      121 ttacactgaa gaaaattctc cggaaatcaa aaatcggccc aatgattgat tcgctttgca
      181 cacgatgaca aaaccgcaaa cagaacgact cggggtttca gctctcgatt acttcttttc
      241 caagaatggt tggctctttc gcgaacagac aacccacgac tatggaattg acgcccacgt
      301 cgagattgtc aagaacgagc gtccgaccgg gagacttatc gcgcttcaaa taaaagccgg
      361 cctcagcttc tttcaagaag aagccgattc cgcttatgta tttagaaccg acgacaagca
      421 catttcgtac tggcttgagc attccatgcc ggtggtcctt gtcttataca accccgatac
      481 agaacaagcg cactggcagc acgttgccag agatacggtc gaaaccactg ggaagggttg
      541 gaagctgagc gtgcctaaga tcagcctctt cgaggagcct gaaaaattct tgaaggcgct
      601 agcagcctta acgcagccag aaccatacat ccggcgtctt aatcgcctac ggatcgaccg
      661 ccattggatg gaattgatcg atcggggata cgaagttcgg gttgaatttt ctgattgggt
      721 taacaagtcg ctacctcgat accaagtcac catatcgacc gataatgaga aggagtcttg
      781 gcctaccctt tatgctcccg gtttgggtat cgaaggaatg ttgcatcact tctttccttg
      841 ggctgatttc tctctggaca tggatgcaca tcagcaagcg gcttatggag cttgggagag
      901 cgaatgctat gcagggcgcg acagcgagac aggcagggtt tactacttca tgtcgttctc
      961 tgagtggtac acgccaccag cagaagatat cgttcccatt tcagaagatg gcgaaacggc
     1021 ttcatatagc ttgctgctaa ctttgaacga ctttgggaaa agtttcctaa tagttgacga
     1081 ctacttggct gaacccgatg cgccagaaac caagggcttc accttggagt agtcggaaac
     1141 gcaacgctgg aactatcatg ccaccagagg ttacgagata gagccgcgct tcgtcagtgc
     1201 gttgggacat tgaacgacag ctttccccga agtccaaggg ctggctgggg tgcagttcag
     1261 tcagttacga acgaaagagt ggaagaagtg gctcttaact gaagtggcat tgaggcgcag
     1321 acttgagggg atttggtatg aatggaatta ttgcgctcaa agcgtttcta atatttgcgc
     1381 caataatgag tcttggggct gcttacggca acaagcatga ctacgctgga gacccattat
     1441 tacagagcgc gcatctttac gcccagattg ctctttccct tgttgcagca accgccgcgt
     1501 tgtgctgggt ggctgcgtac agaatttcaa gcgagaaggc tagatcgagt gtcacgtttg
     1561 cgatttgggc gttatggtta tacggacccg ctctgaattt gattttgcta attattgttc
     1621 cgactttcat ctttcgtccc tttgatgtat cccctgttct acctgccctt gttggcgcga
     1681 caatcaggga cgtcctcata gatggcggtt ttacctggta tttacttcga agcagctaca
     1741 taagagagca gtatcggtaa atgcggtcaa tatggcactc aatctcccgg cttcgctctc
     1801 tgcacgtttc acaatatagc ctcgttgtgc aggttgattt ttctgagtga ccgttttaca
     1861 cgagcgccaa tgactgcaac gggtcgcttg ccgccattca tacccgcgta cacaattccc
     1921 gaagccacac acagccgaga caagaacaat gacatcaatt gccgttgact gcgttgatgg
     1981 cgttggccat ctgcagctga atcgcgccaa cgcgctcaac gcgctggacc tccaattctg
     2041 cacggagata gacgacgcgc tcctcgccct ggacgcacgc gaggaggtgc gggcgatcct
     2101 catctccacg tcgctgaagc acttctgtgc cggtgcggat atccgggaga tgctggacat
     2161 gagcgccgag caggccagcg cgaccgggtt catcggctgc gtttcggcgc cgccccggct
     2221 ccgcaagccc ttgatcgtcg cggtgagggg actggcggcg ggcggagggt gcgaactggt
     2281 ggagatgtgc gacatcgtgc tcgccgccgc ttcggcgcgc ttctgccatc ccgagatcac
     2341 gttgggtgcc atgcccggtg ccggcggtac gcagcggctg gcacgggtcg tgggcaagca
     2401 tgtcgcgctg gacctgctgc tgaccgggcg cgccctgagc gcggacgaag cgctttccgc
     2461 cggcctggtt tcgcgcgtgc ttccggatga agaactcgaa gccgccgcca tgtccgtcgc
     2521 ccggctcgtg gcgtcgtact cgagcccggt cgcctgccgg atcaaggccg ccgtcaatgg
     2581 ggcgcaggtc gggctcgacg ccgggctggc catggagcgc gcgctgttcc acgcatgttt
     2641 ctccgagcac gactttcgcg aggggctcgc cgcgttcacg gagaagcgga agccgagatt
     2701 cgagcatcgt tgagggctcg aaggccggtc gccgcagccg ggcggcgtgg cggaggtgcg
     2761 gcggatcgat catcgccgta agattccgcc cccggcgccc cccgcccgcg caggtaaaat
     2821 gcgcttttgc ccgcccgccc cccgatgccc gcctcccccc cggccccgcg ccgccccgaa
     2881 ctcctcgccc ccgccggctc cctggacatg atgcgcaccg ccttcgccta cggcgcggat
     2941 gcggtgtatg ccgggcagcc gcgctactcc ctgcgcgtgc gcaacaacag cttcggccag
     3001 ctcgacacgc tcgcggccgg catggccgag gcgcacgccg ccggcaagct gttctatctc
     3061 gtcgccaaca tctatccgca caacgccaag ctgcgcacct tcgaggagga catggcgccg
     3121 gtggtggcga tgaggcccga cgcgctgatc atggccgacc ccgggctgat cctgatggtg
     3181 cgcgagcgct ggcccgagtt gccgatccac ctgtcggtgc aggccaacac caccaaccac
     3241 gcgtcggtgc gcttctggca gtcggtgggg gtcaagcgca tcatcctgtc gcgcgagctg
     3301 tcactcgacg aggtcgccga gatccgcgac gcctgcccgg acatggagct cgaggtcttc
     3361 gtgcatggtg cgctgtgcat cgcctactcc gggcgctgcc tgctgtcggg ctacttcaac
     3421 catcgcgacc ccaaccaggg cagctgcacc aactcctgcc gctgggacta caagctgcac
     3481 gaggccgccg acaacgccgc cggcgacgtg caggcctgcg gcggcgcgcc gatcggcaat
     3541 ccgaaggacg ccggcgcggt cggcaccgcc acgcgcagcg cgctcgacac cgcgcagggg
     3601 ctggcgctcg gcggcggtcc gcgccacctc ggcggcagca aggtgtggct gctggaggaa
     3661 ggcacccggc ccggcgagct gatgccgatc gaggaggacg agcacggcac ctacatcctc
     3721 aactcgaagg atctgcgggc gatcgagcac gtgcagcggc tggtggagat cggcgtcgat
     3781 tcgctgaaga tcgagggccg caccaagagc ccctactacg tcgcccgcgc cgcccagggc
     3841 taccggcgcg cgatcgacga cgcggtggcc gggcggccgt tcgatccgcg cctgctcggc
     3901 gagctcgagg ggctggccag ccgcggctac accgacggct tctaccagcg ccattccacc
     3961 ccccagcacc agaactacct gcgcggccac tccgaatccg ggcgcagcct gctggtgggc
     4021 gaggtggtcg gcttcgatgc cgcgcgcggc ctggccgagg tcgaagtcaa gaacggcttc
     4081 ggcgtcggcg accggctgga gttcgtgcag ccggacggca acgccgaggc agtgctggcg
     4141 cggctcttca gcgccaccgg cgaaacgctc gaacgcgtgc cgggcagcgg aaggcgggtg
     4201 tggctggcgc tgccggcaga ggccgatccg gcgcggccct gcttcgtcgc gcgctttctg
     4261 tgaaccgcga agccaccggc tggcggtggt cgtggggcgc gatcgaagcg ggctttgatg
     4321 tgaacacccg gtactgaaga atcccttaat ctgactcccg cggcggacga cccgcccgct
     4381 tccccgctct cccggcggca cctggaaccc ccgctcccat gatcctgaac atcgacctcg
     4441 tctccgactt cgtctgcccg tggtgcttcc tcggcgccgt ccgcctcgac cgcgcgctcg
     4501 ccgagctgcg cgcggcccgc ccggacatcg agccgcgcat caactggctg cccttcttcc
     4561 tcaacccgga caccccgccc gagggcgagc cctaccgcgc cttcctggag ggcaagttcg
     4621 gcggcccggt gaaggccgag gcggtgctgg accaggtgcg cgaggccgcc gccggcgacg
     4681 ggctgcagta cgccttcgag cgcatcgcca cgcgcccgaa cacgctcgcc gcacaccgcc
     4741 tgctgtatcg cgcccaggcc cacggccaca agccggagcg cgtgcgcgcg ctcgcccacg
     4801 cgctgttcgc cgcacacttc caggaaggcc gcgacatcgg cgacctcgac accctggccg
     4861 atctcgccgc cgcctgcggc gaccgccgcg acgtggtgcg cgagtggctg gagagcggcg
     4921 ccgacgccga caaggtgcag cgcatggccg ccgggctgcg ccgccagggc atcgacggcg
     4981 tccccttctt catcctcgac cgccgcctga gcctgtcggg cgcccagtcc gccgcagtga
     5041 tcggcgccgc gctgctgcag gcactggaga ccggcaagcc gtcctgaacg cgccgagacg
     5101 cctgttcgcg cctgccggcg ctcctacaga aaccgccgcg cttccgcctc ctgtaggagc
     5161 ggcggcagcc gcgaatagcg cgatcggacg ggcgacgcgg gcggactcca acgccgcttt
     5221 cgcgcctgcc ggcgctcctg caggaagcgc cgcggatccg ccccatgtag gagcggcggc
     5281 agccgcgaaa aggacgcttg gacgggcgac gagggtgcgg atccccacct cccctctcgc
     5341 gcgtgcgcgc actcccacgc gcccctcggg aacatgcggc gctgcgggag cgtctgagat
     5401 ggcatgacgc acgacaccca ccggaacccc atcgccatgc acgacaccct cgtccttgcc
     5461 gacaccgacc tgcgcgcgct cgccgaggcg cgcgtgctgc tcgagcgccc gagcctggcc
     5521 gcgcgcctga gcagcttcgt cggcagccca ctggagaagg gcatggcgcg cctgcccgcg
     5581 agctggcgcg agcgcatcgg cgggctcgcc cacgacgcgc tgatgaaggc gatggacgcc
     5641 gcggcgaaga ccctgcagcc caccgcccag cccgcctcgc cgcgcctgca caagctgctc
     5701 ggctcggtga gcggcgcagg cggcggtgcc ttcggggtcg ccgggctgac ggtggagatc
     5761 ccgctgtcga ccgtgctgat catgcgctcc atcctcgaca tcgcgcgcgg cgagggcgag
     5821 gacatcggcg gcacgcaggc ccggctcgcc gcgctcgagg tgttcgcgct cggcggcaac
     5881 gccagcggcg acgacgcggc cgaggcgggt tactacgcgg tacgcgcggc gctcgcgacc
     5941 acggtctccg aggccgcgcg ccacttcgcg cagaaggggc tgtcgggcga gggcgcgccc
     6001 gcgctggcgc ggctgatcac gatggtggcg gcgcgctaca aggtgcagct cacccagaag
     6061 gccgccggca tgctggtgcc ggggatcggc gcggcagcgg gggcgacgat caacctgatg
     6121 ttcatggacc acttccagtc ggtcagccgc ggccacttca ccgtgcgccg gctggagcgg
     6181 cgctatggcg aggcggcagt gcgcgcggcg tggcagacgc tggggcgctg agggcgggcg
     6241 ttcggggacc gggctgaacg cgggtacgca tcggagcgcc ccgttcgcgg ctgccgccgc
     6301 tcctacagga ggcggaagcg cggcggttcg tgtaggagcg ccggcaggcg cgaaggcggc
     6361 cgtgaaatcc gcnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnctcctaca
     6481 cggggcggag gcgcggcggt tcgtgtagga gcgccggcag gcgcgaaggc ggccgtgaaa
     6541 tccgcaccgg cgtcgcctgc ccgagcgccc gttcgcggct gccgcagctc ctacacgggg
     6601 cggaggcgcg gcggttcgtg taggagcgcc ggcaggcgcg aatgcggccg ttaaattcgc
     6661 accggcgtcg cctgccaaac cgcccgttcg cggctgccgc cgctcctaca gggggcggga
     6721 cacgcggcgg ttcttctagg agcgccggca ggcgcgaatg ctcaagccgt ggcgccggcc
     6781 ggcgggtagg cggcgacgaa ttcgtcccag ggcagcggcg ggttgaaatg gaagccctgc
     6841 gcgaggtcgc agccctggcg gcgcagcacg ttcaggtggg ctgcggtctc gacgccctcg
     6901 gcgaccacgc gcaagcccag actgtggccg agcgagacga tcgccgacac cagcgccgcg
     6961 tcacgcgtgt tgcggtcgat gccgcgtacg aacaggcggt cgatcttgag ctcgtcgatc
     7021 gggaagcgct tgaggtaggc gagcgacgaa tacccggtgc cgaaatcatc gatcgccagg
     7081 cacacgccga gcgcgcgcag gtggtcgagg cgcgcgagag cgcggtcggt gtcgtccatc
     7141 agcatgctct cggtgagctc cagcgtcagg tcgcccgggg tcatgccggt ctcggcgagc
     7201 acgctggcca ccatcgcggc gaagccctcc tcgcggaact ggcgcgccga aatgttcacc
     7261 atcatgtgca gcggaccgcc gccggcctcg caccaccgcc ggtgatgctc gcaggcgctg
     7321 cgcagcaccc actcgccgat cggcacgatc aggccggtgt cctcggcgag cgggatgaag
     7381 tcggccggcg acaccagccc gaggtcgggg tgacgccagc gcagcaaggc ctcgacggcg
     7441 accagctcgc ctccctcggc ccccatcacc ggctggaagt agagctgcag ctcgtcgcgc
     7501 ggcaaggcgc ggtgcagcgc ggtctcgagc gcgaggcgct cgagcgagcg cgcgttcatc
     7561 gccggctcga agagctggaa gctgttgcgc ccctcgtcct tggcgcggta catcgccacg
     7621 tcggcgtgct tgaccagggt gtcggcatcg cgcgagtcgt cgggatacac ggcgacgccc
     7681 acgctggtcg tcaccaccag ctcgcggccc tcgacattga ccgggcgccg cagctccgcg
     7741 accagcctgc gcgccatcgt cgccgcctcg tccgggccgg acaggttgtt gagcacgacg
     7801 aggaactcgt cgccacccat gcgcgccacg gtgtcgtcct cgcgcaggct gacgcgcagg
     7861 cgggcggcga tctcgaccag cagcttatcg cccaccgtgt ggccgaggct gtcgttgatg
     7921 cgcttgaagc ggtcgaggtc gacgaacatc accgccagcc ggcagcgcag gcgggcggcg
     7981 tgggcgagct cgacctgcag gcggtcgtcg agcaggcggc ggttgggaag gccggtgagc
     8041 gggtcgtaat aggcgagatc gcggatgcgc gcctcggtct ccttgagccg gctgatgtcg
     8101 gtgaacagcg ccgcgtaatg ggtcagcaca ccctcgccgt cgcggatcgc ggtgatgtgc
     8161 agcagctgcg gatacacctc gccagtcttg cgccggttcc acacctcgcc ctgccaatga
     8221 ccgtcgcgca gcagtccgtc ccacatgcgc gcatagaagg ccgggctctg gcggccggag
     8281 ttgagcaccg aagggttgag cccgaccacc tcttccggtg cgtacccggt catgcgcgtg
     8341 aaggcggggt tcaccgagag gatgcgcgcg tgcgcgtcgg tgaccatcac cccctcgagc
     8401 gagctctcga tgaccttctc ggccaggtag aggtcgcgct gcgaggcgct cagcgcgagg
     8461 tcgcgcgcgc gcagggcgtc gtgcagctcg tgcacgtagg ccagctccat gccgctgagg
     8521 atgtccttga agctgaccag gtcgacgagt ccgccctcgg cgtcgagcac gccgatgtgg
     8581 cggatctggc gctcgacgag cagcatgcgc acgcggtaca ggctgttgtc cgcgcggcag
     8641 gtgacgagcg gccggctggc gagctcgccg agcgcgcggt cgggcgcacg ctcggccacc
     8701 aggcgggtga cgtcgcgttc ggtgaggatg ccgtagcggc cctcgggcgt ggaggccgcg
     8761 ggagcgccgt aatccaccac gaccgcgtcc acgccgccct cgcgcattcg ccgggtcgcg
     8821 tcgcccagcc ccgctgccgc gggcagcgcg tgcaggccgc ccttgaccag cgcgtccacg
     8881 cgacgcagct tgaggtagtg ctcgatgccc tggttgagca ccacgtcggt ctgcgacacg
     8941 atgcccacgc gccgcccggc gtcgtcctcg accacgtagt ggcgcacgtg ctcctcgcgg
     9001 aagcgcaccg tcagttcgtg cagcggggtc gccaccgaca ccgcgcgcac cggcgagctc
     9061 atcacggcac gcaccggcag ggcaaaggtc gcggggtcgt cgaaattcac ccgcagcgcg
     9121 tcgcgctcgg tccagatgcc caccacgcgg tcgtcctcga ccaccaggat cgagctcacc
     9181 cgacgttcgc tcatgcgccg cgcggcctcg tgcaggggct cctcgggggc gcactcgagc
     9241 aggttgcgac cgatgatctc gccgacgcgg atctcgtcgg tgcgaggcat ggagaaggcc
     9301 tcctcgttca ggaggaagcc agattcagga cggttcatgg gggactcgag acaacttcta
     9361 gacctcgtat aacgaccgca agagactgaa acctgagggg atatgccgca ttgtcgcatc
     9421 cgtggggctg catgccgacc ccggctaacc cgcagggatg cattcaccct gcggtaacac
     9481 gccgggcgca tgctgcccga atgcttcgcg tgctgatgat ctccgatgtc ttctttccgc
     9541 gtgtcaacgg cgtctccacg tcgatcgcga cctttcgccg cgcgctcgcc gagcagggtg
     9601 tcgaggtccg cctgatcgcg ccgcgctacg ccggcgaggc cgcggagccc ggcatcgtgc
     9661 gtatcccggg acgacgcctg ccgctcgacc ccgaggatcg cctcgtcgat gcgcgcgcga
     9721 tgcacgccgc cgcgcgactc gaggccgccg ccagcgacct ggtgcacatc cagaccccct
     9781 tcctcgccca ccgcgccggg ctgcgcgctg cgcgcgccga ggggcggccg gtgctgctga
     9841 cctaccacac cttcttcgag gaatacctcc accactacct ccccttcctg cccgccggcg
     9901 tgctgcgcgg gctggcgcgg cgggtgtcgc gcacgcagtg caacgcggtg gatgcggtgg
     9961 tggtgccgtc gaccgcgatg cacgagcgcc tcaccggcta cggcgtgcgc agcccgatgg
    10021 agatcctgcc caccggcatc ccgctgcagg acttcgccgg cggcgacggc ccgcacttcc
    10081 gccgcctcta cgacatcccg gaggacgcgc cgatggcgct ctacatcggc cgcgtcgcgc
    10141 acgagaagaa catcggcttc ctgctcgagg tcgccgcccg gctcaaggcg cgccggcccg
    10201 acttcgtcct cgtggtcgcc ggcgagggcc cggcgagcgc ccgcctgcag cgccaggcgc
    10261 tcgccgccgg gctggacaac acggtgcgct tcgtcggcta cctcgagcgc cgcaagcgcc
    10321 tccccgactg ctacgccgcc gccgacgtgt tcgtgttcgc atcgcgcacc gagacccagg
    10381 gcctggtgct gctcgaggcg atggccgccg ggctgccggt ggtggcgctg tccgcgatgg
    10441 gcaccaccga catcctcggc cccgagcgcg gcgcacgcat cgcccctgac gaccccgacg
    10501 gcttcgccgc cgtggtcgtc ggcgtgctcg ccgacccccg cctgcgccgg cggctcgccg
    10561 ccgaggcacg cgattacgcc gccgagtggg cggacggcgt gatggccggg cgcctcgccg
    10621 cgctctaccg cagactgctg gccgcgccgc aggccgcgca atcgcagaac gcatcgcgca
    10681 tcgccgccac ccgctgagtc gctccgcaag cgcggggcga gacttgcgcg tgtgcgcgcc
    10741 agcgcacaag atgcgccgat cggacacgga gcctcccatg aacaccacca cgctcacgat
    10801 caccggcatg cgcgacgagg agtgcctgcg cctggtgacc aacgccatcc aggacctgcc
    10861 cggcatcggc tacctggaga tctcgctcgc gaccggcgcc gccaccatcg agcacggcgc
    10921 cttcgtcgcc gaatccgaca tccatcaggc gatcgaggac gcgggcttcg gcgtgcgctg
    10981 aacacggcca ccgtgccgcc ggcacgggaa cctgcgcgcc caagcgcgct cgaagcgcga
    11041 tccatccgcc agccgcctcc agccttgacg ccctccctcc acagctttcc cggcggtctc
    11101 gccttcgtcg acatcgagac caccggcggc cccgcccagc gcgaatcgat caccgaggtc
    11161 ggcatcgtcc aggtcgacga ggacggcgtg cgcgagtggt cgacgctggt gcgccccgag
    11221 tcgcgcatcc ccgagaccat ccagcgcctc accggcatcg acgacgacat ggtcgccgac
    11281 gcgccgcgct tcgcggacat cgccgacgaa gtcttcgacc gcctcgatgg ccgcctcttc
    11341 gtcgcccaca acgcgcgctt cgatcacggc cacctgcgcg ccgccttccg ccgcgccggg
    11401 ctcgacatgc gcccgcaggt gctgtgcacc gtcaagctgt cgcgccggct gttccccgac
    11461 caccgccgcc acggcctcga ccacctcatc gaacgccacg gcctggtggt cgccgaccgc
    11521 caccgcgcgc tcggcgacgc ccagctgctg tggcagttct ggcagaagat ccacgagcgc
    11581 ttcccgcccg gccacatcga ggccatggtg cgcgagctcg tcggccaccc cagcctgccg
    11641 cctcacctcg accccgagca ggtcgccgag ctgcccgaca cgcccggggt atatctgttc
    11701 tatggcgagc gcgacggcgg cacggagggt ggcacggaca gcagcgcgct gccgctctac
    11761 atcggcaaga gcacccgcct gcgcagccgc gtgctgtcgc acttcgccgc cgaccacacc
    11821 agcgaccgcg agctcagcct cag
//
LOCUS       DAOTIN010000101        11819 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_6452_length_11819_cov_9.088150, whole genome shotgun sequence.
ACCESSION   DAOTIN010000101 DAOTIN010000000
VERSION     DAOTIN010000101.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 11819)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 11819)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11819
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6452_length_11819_cov_9.088150"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..99
                     /locus_tag="P5537_13015"
     CDS             <1..99
                     /locus_tag="P5537_13015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HRV79004.1"
                     /translation="INKDPEAPIFQVADYGLVGDLFQVVPELTGAL"
     gene            121..786
                     /locus_tag="P5537_13020"
     CDS             121..786
                     /locus_tag="P5537_13020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000041 - transition metal ion transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HRV79005.1"
                     /translation="MDLPASLLSAGVEAAVYALAALGLLALARRLPWKELAGGVQLNV
                     LFGFAVCLTLIWSMKAGVKPGLNLHLLGAMAATLALGPWKAVAALALALCGITLNGAL
                     EWGDWPANFVLMVLVPVAVASGLHRLVERLLPAHFFIFIFVTGFAGSALTVMAQGLTA
                     STVLALSGAYSAGFLWSDYLPFFLLLGFSEGWISGAIITLMVVYRPEWVSAFDDRRYL
                     LDK"
     gene            819..2615
                     /locus_tag="P5537_13025"
     CDS             819..2615
                     /locus_tag="P5537_13025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HRV79006.1"
                     /translation="MSQYNAPIRDMQFVMRELAGLDEVMQLPGNEEVSADLVDAILEE
                     ADKFASGVLAPLNWTGDQEGAKWNDGEVATAPGWKDAYTQFAESGWTALPCDPEYGGQ
                     GLPKLLATAVMEMWKSANMAFSLCPMLTSGAIEALMLRGTDEQKNLYLPKMIAGEWTG
                     TMNLTEPNAGSDLAAVRTKAEPQGDGTYKIFGQKIFITYGEHDLTDNIIHLVLARLPD
                     APEGVKGISLFVVPKFMVDADGSLGARNDVHCVSIEHKLGIHASPTAVLAFGDKGGAI
                     GTLVGEPNRGLEYMFIMMNEARFAVGMEGLALSERSYQHALQYAKDRIQGTDAGVRGG
                     PKVNILHHADVRRLLMNMKSKTEAMRALAYVVGAAFDKAHNHADEAVRAQNQAFVDLM
                     IPVVKGWCTENSIDVTSDGVQVHGGMGFIEETGAAQHFRDARITTIYEGTTAIQANDL
                     IGRKIARENGATVAAVVKTMRAVEAELGGVQDEAFAAIARALGNGIAALEEAVAYILA
                     TYSKDIKAASVGSVPFLKLLGIVAGGWQMARAALVAKRKLEAGEGDAGFYKAKIVTAR
                     FYADHVLAQAGGLAYTVVNGAPGALELSEELF"
     gene            complement(2777..3559)
                     /locus_tag="P5537_13030"
     CDS             complement(2777..3559)
                     /locus_tag="P5537_13030"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HRV79007.1"
                     /translation="MKHFPSRLAITLLAGFLALPALAASPVAKVNGVTIPGERAEAML
                     TEQRAQGAPDGEQLRNAVREELIRREVLSQEAGKKGLDKKADVKAQMEMARQAILIRA
                     YLQDYVRANPISDADLMKEYDAIKGRMGDKEYKPRHVLVETEDQAKAIIARLQNGTAF
                     EEVAKESRDPGSKERGGELGWSNPAMFVKPFSDAMVRLEKGKYTATPVKSDFGYHVIQ
                     LDDVRDVQPPPFDEVKPQLQQRLQQQKVERHVLELREKAKVE"
     gene            complement(3570..3857)
                     /locus_tag="P5537_13035"
     CDS             complement(3570..3857)
                     /locus_tag="P5537_13035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BolA family protein"
                     /protein_id="HRV79008.1"
                     /translation="MSATRVERIRAALQDRFAPTRLEIGDDSALHAGHAGAREGGGHY
                     RVFIVAEAFQGCSRVLRQRMIYDAVGDMMHKDIHALAIRALTAAEAESQGH"
     gene            complement(3854..4153)
                     /locus_tag="P5537_13040"
     CDS             complement(3854..4153)
                     /locus_tag="P5537_13040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004341655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciI family protein"
                     /protein_id="HRV79009.1"
                     /translation="MFYALIGEDAPGALETRLAVRPQHVARLEALRDEGRLLLAGPMP
                     AIDSPDPGPAGFAGSLIVAEFDSLASAEAWLREDPYVQQGVFARTTVRPFRKTLP"
     gene            complement(4153..4761)
                     /locus_tag="P5537_13045"
     CDS             complement(4153..4761)
                     /locus_tag="P5537_13045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septation protein A"
                     /protein_id="HRV79010.1"
                     /translation="MKFLFDLLPVILFFAAYKIGGANPEASHALAAGWLGDGIAVSQA
                     PILIATFVAILATFLQIALVWVKHRKVDTMLWISLAIIVVFGGATLFFHNPTFIKWKP
                     TALYWLFGGVLLGSAWLLGRNLIRAMLEAQIKLPDPVWARLNLAWAGFFIAMGVLNLW
                     VAYNFSEEAWVNFKMFGGMGLMLAFVLAQGFYLSRHMEEESN"
     gene            complement(4758..6173)
                     /locus_tag="P5537_13050"
     CDS             complement(4758..6173)
                     /locus_tag="P5537_13050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HRV79011.1"
                     /translation="MAESVETIAGPVRKRLLPSTLLWQTFLLVALLLIVALGSWVQIF
                     RYFQEPARARDVAQMVVSVINLTRTALINADFDRRVDLLIDLAALEGIRIYPAEATDE
                     LEPLGDTRPLRLLTADVRRQLGDHTRFASRWKTLDGFWVSFRLDPDDANDEYWVMLPP
                     ERIENPDDFGWLGWGGGALLAALLGAFLIVARVSAPLRQLARAARIVGSGERPPPQPE
                     SGPQEIALVARAFNRMADNLARMDEDRALILAGVSHDLRTPLARLRLGIEMSGAPDDE
                     VSAMVADIDEMDRIIGQFLDFGRGDTQEPTAAIDLATLAREVTEPYRLRGVDLRLDIP
                     ESLFAQARALSIRRALANLIDNALRYAGTDAPLEVTVSSAGGQARIEVADRGPGIPES
                     EIERMRQPFTRLDKARGNTKGAGLGLAIVDRVMRAHHGRLELSARAGGGLLAALCLPL
                     AAPAGEQDRMRRSVPSEPDRP"
     gene            complement(6173..6946)
                     /gene="ompR"
                     /locus_tag="P5537_13055"
     CDS             complement(6173..6946)
                     /gene="ompR"
                     /locus_tag="P5537_13055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator OmpR"
                     /protein_id="HRV79012.1"
                     /translation="MNQKNRYRILVVDDDARLRELLSRYLQEQGFSVKAVGDAPMMDR
                     ALHREHYDLIVLDLMLPGEDGLSICRRLRAAENQIPVIMLTAKGDDVDRIVGLEMGAD
                     DYVAKPFNPRELVARIQAVMRRQPQTLPGAPTPEDEIVVFGRVKVNLGTRVLVRDGEE
                     IQLTTGEFSLLKVLLTHPRQPLSRDKLMELARGREYGVFDRAIDVQVSRLRKLVEDDP
                     AKPRYIQTVWGFGYVFVPDEQKNGEDKDGEPESPSGSEA"
     gene            7317..7544
                     /locus_tag="P5537_13060"
     CDS             7317..7544
                     /locus_tag="P5537_13060"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79013.1"
                     /translation="MRFIVGGEEQAQRFRPAGAGERPEWRDTLSEQHKDRDGARERRR
                     MSDEERSDLRRHMRDAARGAYREEPGRKPQR"
     gene            7692..8384
                     /gene="tsaB"
                     /locus_tag="P5537_13065"
     CDS             7692..8384
                     /gene="tsaB"
                     /locus_tag="P5537_13065"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HRV79014.1"
                     /translation="MNILSIETATEHGSVALLHGDELLVRRIQGAANHSEAVLRDLRE
                     LLAEAGLAVAQLDAVAFGAGPGAFTGLRLACGVAQGVALAADLGVAAVGSLQALALQV
                     GAPRVLAATDARMGEIYCATFVCDGEGVPRLQGTLRCCAPLDLELPPGEWSAAGSAFR
                     AWPEELEARTAGRLVACQPDLYPRAEEVARLGAIQARDAVLVAPELAAPLYVRDKVAL
                     TTAERRARGGRA"
     gene            8384..8830
                     /gene="rimI"
                     /locus_tag="P5537_13070"
     CDS             8384..8830
                     /gene="rimI"
                     /locus_tag="P5537_13070"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HRV79015.1"
                     /translation="MQALAFAPMREEDLDWVSAREAELHAHPWSRGNFADSLASGYDA
                     WVLTCDGVSAGYAIVMNVLDEAHLLDIGIVAALQGRGLAMRFLDWLAEGAKARGACDF
                     YLEVRPSNAAALRLYARSGFVEIGRRRGYYPAADGREDAIVMRRTL"
     gene            8875..9768
                     /locus_tag="P5537_13075"
     CDS             8875..9768
                     /locus_tag="P5537_13075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HRV79016.1"
                     /translation="MGLGPIWRLRARKAEADVTEDSAPEDSAPAWTGTAAAIATPRAE
                     APPTPMARSVEPEPAAGPQPRPAHPAAPRNAEPPRIHAARPQPPATPTPAATLAAPAA
                     PDPARSARIATLDWDALEAGIRDCKACVLCERRKQAVPGVGDRQARWMLVGEGPGAEE
                     DQRGEPFVGQAGRLLDNMLAAIGLKRGEDVYIANAVKCRPPHNRTPERGEIAACLPYL
                     DRQIALVQPQLLIALGRPAAQALLDREIAISAARGKRFERAGVAVVVTYHPAYLLRNP
                     QDKAKAWEDLCFARRLMAGTG"
     gene            complement(9851..11101)
                     /gene="lplT"
                     /locus_tag="P5537_13080"
     CDS             complement(9851..11101)
                     /gene="lplT"
                     /locus_tag="P5537_13080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid transporter LplT"
                     /protein_id="HRV79017.1"
                     /translation="MPLGFYIIMAAQFFSALADNALLIIAIAMLRDMAAPSEYEPLLK
                     LFFTVSYVALAAFVGAFADSMPKWRVMLISNTIKIGGCLMLFLGTHPLFAYAVIGLGA
                     AAYSPAKYGILTEYLPHRLLVVANGWIEGLTVAAIIVGTVVGGIMIRGDVSTWLMGLG
                     LPGVGSAFGAAVLMVGTLYLVAAIFNMYIPDTGVDHKPLKSNPLYLLHDFNHCLRLLW
                     RDKLGQISLAVTTLFWGAGATLQFIVIKWAEHNLGMNLSQASMLQGVVALGVATGSVL
                     AARYITLRRAVNVIPLGIAMGLGVMTMVGVTEAWIAMVLMVIVGGLAGFFVVPMNALL
                     QHRGHILMGAGHSIAVQNFNENLSILVMTGTYALLIVLGLSINTVIVMFGLFVAGTML
                     LVKRRHDANQREFDNVALLEDRLH"
     gene            11319..>11819
                     /locus_tag="P5537_13085"
     CDS             11319..>11819
                     /locus_tag="P5537_13085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HRV79018.1"
                     /translation="MADRRLQVFHAVAKHGSFTRAAEHLHMTQPAVTFQIKQLEEHFD
                     TRLLDRGHGKITLTAAGELVLAYAERILGLSAELDSRVSELTDELAGQLRIGTSTTIA
                     AYWLPQVLESFKRRYPGVLPRVVVGTSKLTEDRVAARDLDLGLIEIATEQPSIERRSA
                     ASDDLLV"
BASE COUNT         1853 a         4000 c         4110 g         1856 t
ORIGIN      
        1 atcaacaagg atcccgaagc gccgatcttc caggtggccg actacggcct cgtgggcgac
       61 ctgttccagg tggtgccgga actgaccggg gcgctctgac cggacgcggg gaacgcgggc
      121 atggatctcc cggcgtcgct gctttcggca ggcgtcgagg ctgcggtgta cgcgctcgcc
      181 gcgctgggat tgctcgcgct cgcgcgcagg ctgccgtgga aggagctcgc cggcggcgtg
      241 cagctgaacg tcctgttcgg cttcgcggtc tgtctcacgc tgatctggag catgaaggcc
      301 ggggtcaagc ccggccttaa cctgcacctg ctcggcgcga tggcggcgac gctcgcgctc
      361 ggaccgtgga aggcggtcgc cgcgctcgcg ctggcactgt gcgggatcac cctcaacggc
      421 gcgctggagt ggggcgactg gcccgccaac ttcgtgctga tggtgctggt tccggtggcg
      481 gtcgcgagcg gcctgcatcg cctggtcgag cgcctgcttc cggcgcactt cttcatcttc
      541 atcttcgtga ccggctttgc cggttccgcg ctgaccgtga tggcacaggg gctgaccgcc
      601 tcgaccgtgc tggcgctgtc cggcgcgtat tccgcaggct tcctgtggag cgactacctg
      661 ccgttcttcc tgctgctcgg gttttccgag ggctggatca gcggcgcgat catcacgctg
      721 atggtggtgt atcggcccga atgggtgagt gcattcgacg atcgccgcta tctgctcgac
      781 aagtagcagg ctgttcaacc ttttccggag cgccaacaat gagtcaatac aacgccccca
      841 tccgcgacat gcagttcgtg atgcgtgagc tcgccggtct cgacgaagtc atgcagttgc
      901 ccggcaacga ggaggtctcg gccgacctcg tggacgcgat cctggaagaa gccgacaagt
      961 tcgccagcgg cgtgctcgcc ccgctgaact ggaccggcga ccaggaaggc gccaagtgga
     1021 acgacggcga ggtcgccacc gcgccgggct ggaaggacgc ctacacgcag ttcgccgagt
     1081 cgggctggac cgcgctgccg tgcgatccgg aatacggcgg ccagggcctt cccaagctgc
     1141 tcgccaccgc ggtcatggaa atgtggaagt cggccaacat ggccttctcg ctgtgcccga
     1201 tgctgaccag cggcgccatc gaggccctga tgctgcgcgg caccgacgag cagaagaacc
     1261 tctacctgcc caagatgatc gccggcgagt ggaccggcac gatgaacctc accgagccga
     1321 acgccggttc cgacctcgcc gcggtgcgca ccaaggccga gccgcagggt gacggcacct
     1381 acaagatctt cggccagaag atcttcatca cctacggcga gcacgacctc accgacaaca
     1441 tcatccacct cgtgctcgcc cgcctgccgg acgcgcccga gggggtgaag ggaatttcgc
     1501 tgttcgtcgt gcccaagttc atggtcgacg ccgacggtag cctgggcgcg cgcaacgacg
     1561 tgcattgcgt gtcgatcgag cacaagctcg gcatccacgc cagcccgacc gccgtgctcg
     1621 ccttcggcga caagggcggc gcgatcggca ccctcgtcgg tgagccgaac cgcggcctcg
     1681 agtacatgtt catcatgatg aacgaggccc gcttcgcggt cggcatggaa gggctggcgc
     1741 tgtccgagcg ttcctaccag cacgccctgc agtacgccaa ggaccgcatc cagggcaccg
     1801 atgccggcgt gcgtggcggt ccgaaggtca acatcctgca ccacgccgac gtgcgccgcc
     1861 tgctcatgaa catgaagagc aagaccgagg cgatgcgcgc gctcgcgtac gtcgtcggcg
     1921 ccgccttcga taaggcgcac aaccacgccg acgaggcggt gcgtgcgcag aaccaggcct
     1981 ttgtcgacct gatgatcccg gtggtcaagg gttggtgcac cgagaactcg atcgacgtca
     2041 cctcggacgg cgtgcaggtg cacggcggca tgggcttcat cgaggagacc ggcgccgcgc
     2101 agcacttccg cgatgcccgc atcaccacca tctacgaggg cacgaccgcg atccaggcca
     2161 atgacctgat cggtcgcaag atcgcgcgcg agaacggcgc caccgtcgct gccgtggtca
     2221 agacgatgcg tgctgtcgag gccgagctcg gcggcgtgca ggacgaggcc ttcgcggcca
     2281 tcgcgcgtgc gctcggcaat ggcatcgcag cgctggaaga ggccgtggcc tacatcctcg
     2341 ccacctactc caaggacatc aaggcggcct cggtcggctc ggtgcctttc ctgaagctgc
     2401 tcggcatcgt cgccggcggc tggcagatgg cgcgcgccgc gctggtcgcg aaacgcaagc
     2461 tcgaggcggg cgagggcgac gcgggcttct acaaggccaa gatcgtcacc gcgcgcttct
     2521 acgccgacca tgtgcttgcg caggccggtg ggctggccta caccgtcgtc aatggcgcgc
     2581 cgggcgcgct cgagctgagc gaagagctgt tctgatcggg cagtccccgg cgcgagagcg
     2641 acggggcggc cgcacgaaaa aaccgctgcc gggctttcgt ccgcagcggt ttttgttgtg
     2701 tcgggtccgg cgcgcgcaag cactccggta ccggcttcat gcaggcgcgc cggcaaggcg
     2761 cgccccggac gagtgcttac tcgaccttgg ccttctcgcg cagctcgagc acgtgacgct
     2821 cgaccttctg ctgctgcagg cgctgctgca gctgcggctt gacctcatcg aacgggggcg
     2881 gttgcacgtc gcgcacgtcg tcgagctgga tgacgtggta accgaagtcg ctcttgaccg
     2941 gggtcgccgt gtacttaccc ttttcgagcc ggaccatcgc gtccgagaac ggcttcacga
     3001 acatggcggg gttgctccag ccgagttcgc cgccgcgctc cttggagccg gggtcgcgcg
     3061 actccttggc gacttcctcg aaggcagtgc cgttctgcag gcgcgcgatg atcgccttgg
     3121 cctggtcctc ggtctcgacc agcacgtggc ggggcttgta ttccttgtcg cccatgcggc
     3181 ccttgatcgc gtcgtattcc ttcatcaggt cggcgtcgct gatcgggttg gcgcgcacgt
     3241 agtcctgcag gtaggcgcgg atcaggatgg cctggcgggc catttccatc tgcgccttga
     3301 cgtccgcctt cttgtccagg cccttcttgc ccgcctcctg gctcagcacc tcgcggcgga
     3361 tcagctcttc acgcactgcg ttgcgcagct gctcgccatc cggcgcaccc tgggcgcgct
     3421 gctcggtcag catggcctcg gcacgctcgc cgggaatcgt gacgccgtta accttggcca
     3481 ccggggaggc ggcgagggcg ggcagcgcga ggaagccggc gagcagggtg atggcgagac
     3541 ggctcgggaa atgtttcatg gagattcctt caatgtcctt gtgattcggc ctcggcggcc
     3601 gttagcgcgc ggatggcgag ggcatggatg tccttgtgca tcatgtcccc gaccgcgtcg
     3661 tagatcatac gctgccggag cactctgctg cagccctgga aggcctccgc cacgatgaaa
     3721 acccggtagt gccccccgcc ctcgcgggcg cccgcgtgac cggcgtgcag cgcgctgtcg
     3781 tcaccgatct cgagtcgtgt cggcgcgaag cggtcctgca gtgcggcgcg gatgcgttcg
     3841 acccttgtgg cgctcatggc agggtcttcc ggaacgggcg caccgtggtg cgggcgaaga
     3901 cgccttgctg cacgtagggg tcttcccgca gccaggcctc ggcgctggcg agcgagtcga
     3961 actcggcgac gatcaggctg ccggcgaagc ctgcgggacc ggggtcgggc gagtcgatcg
     4021 cgggcatcgg tccggcgagc agcaggcggc cttcgtcgcg caaggcctcg aggcgtgcga
     4081 cgtgttgcgg acggacggcc aggcgcgtct cgagggcgcc gggagcatcc tcaccgatca
     4141 gggcgtagaa catcagttgc tttcctcttc catgtggcgg gacaggtaga acccttgggc
     4201 gagcacgaag gccagcatga gccccatgcc gccgaacatc ttgaagttga cccaggcctc
     4261 ttcgctgaag ttgtaggcga cccagagatt gagcacgccc atcgcgatga agaagccggc
     4321 ccaggcgagg ttgagccgcg cccacaccgg gtcgggcagc ttgatctggg cctccagcat
     4381 ggcacggatc aggttgcgcc cgagcagcca ggccgagccc agcagcacgc ccccgaacag
     4441 ccagtacagc gcggtcggtt tccacttgat gaaggtaggg ttgtggaaga acagggtggc
     4501 gccgccgaac acgacgatga tcgccaggct gatccacagc atggtgtcga ccttgcggtg
     4561 cttgacccac accagcgcga tctgcaggaa ggtggcgagg atggcgacga aggtggcgat
     4621 caggatcggg gcctgcgaga ccgcgatgcc gtcgcccagc cagcccgcag cgagcgcgtg
     4681 cgaggcttcg gggttggcgc cgccgatctt gtaggcggcg aagaagagga tcaccggcag
     4741 gagatcgaag aggaatttca tggtcggtcc ggttcgcttg gcacggagcg ccgcattcta
     4801 tcctgttccc ctgcgggcgc cgcgagtggc aggcagagcg cggccaggag gccgccgccg
     4861 gcgcgggcgg aaagctcgag ccggccatgg tgcgcgcgca tgacccgatc gacgatggcg
     4921 aggccgaggc ctgcgccctt ggtgttgccg cgcgccttgt ccagccgtgt gaacggctgg
     4981 cgcatgcgct cgatctcgct ctctgggatg cccggtccgc ggtcggcgac ctcgatgcgc
     5041 gcctgccccc ccgcgctgga gaccgtcacc tccagcggag cgtccgttcc cgcgtagcgc
     5101 agcgcgttgt cgatcaggtt ggcgagcgcg cgccggatcg acagcgcgcg cgcctgggcg
     5161 aacaggctct cggggatgtc gagccgcaag tccacgccgc gcaggcggta gggctcggtc
     5221 acctcgcgcg ccagggtcgc gaggtcgatc gccgcggtgg gttcctgcgt gtcgccgcgg
     5281 ccgaaatcga ggaactggcc gatgatgcga tccatctcat cgatgtccgc gaccatcgcg
     5341 ctcacctcgt cgtcgggcgc gcccgacatc tcgataccga ggcgcaggcg cgccagcggc
     5401 gtgcgcaagt cgtgagagac accggccagg atcagcgccc gatcctcgtc catgcgcgcg
     5461 agattgtccg ccatccggtt gaaggcgcgc gcgacgaggg cgatctcctg cgggccgctt
     5521 tcgggttggg gaggcggacg ctcgccgctg cccacgatgc gtgcggcgcg cgcgagctgg
     5581 cgcaggggcg cgctcacccg ggccacgatg aggaaggcgc cgagcagcgc ggcgagcagc
     5641 gcgccaccgc cccagcccag ccagccgaag tcgtccgggt tctcgatgcg ctcgggcggc
     5701 agcatcaccc agtactcgtc gttggcgtcg tcggggtcga ggcggaagct cacccagaag
     5761 ccgtcgagcg tcttccagcg cgaggcgaag cgggtgtggt cgccgagctg gcgacgcacg
     5821 tcggcggtga gcaggcgcag cggccgggtg tcgccgagcg gctcgagctc gtcggtggcc
     5881 tcggccggat agatgcggat gccttcgagc gcggcgagat cgatcagcag atcgaccctg
     5941 cggtcgaagt cggcgttgat cagcgccgtg cgggtcaggt tgatgaccga cacgaccatc
     6001 tgcgcgacgt cgcgggcgcg cgccggttcc tggaagtaac ggaagatctg cacccagctg
     6061 ccgagcgcaa cgatgagcag cagcgcgaca agcagaaagg tctgccagag cagggtgctc
     6121 ggcagcaggc gtttgcgtac cggaccggcg atggtctcga cggattcggc catcaggcct
     6181 cgctgcccga gggggattcg ggctcaccgt ccttgtcctc gccgttcttc tgttcgtcgg
     6241 gaacgaagac gtagccgaag ccccagacgg tctggatgta gcgcggcttt gcggggtcgt
     6301 cctcgacgag cttgcgcagg cgcgagacct gcacgtcgat ggcgcggtcg aacacgccgt
     6361 attcacgccc gcgcgcaagc tccatgagct tgtcgcgcga aagcggctgg cgcgggtggg
     6421 tgagcagcac cttgagcagc gagaactcgc cggtggtgag ctggatctcc tcgccgtcgc
     6481 gcaccagcac gcgcgtgccc aggttaacct tgacccggcc gaacacgacg atctcgtcct
     6541 cgggcgtggg tgcgccaggc agcgtctgcg gctgccggcg catcaccgcc tgaatgcgcg
     6601 caaccagctc gcgcgggttg aagggcttgg cgacgtagtc gtcggcgccc atctccagtc
     6661 cgacgatgcg atcgacgtcg tcgccctttg cggtcagcat gatgacgggg atctggttct
     6721 cggccgcgcg cagccgacga cagatcgaca ggccatcctc gccggggagc atcaggtcga
     6781 gcacgatcag atcgtagtgc tcacggtgca gggcacgatc catcatcggc gcgtcgccga
     6841 cggccttcac cgagaaaccc tgctcctgca ggtagcggga caacaactcg cgcaggcgcg
     6901 cgtcgtcatc caccacgaga atgcgatagc gatttttctg gttcatgtat gaaatgctag
     6961 cctgactcgc gggcccgtgc cagccttccc ggagcgcgca gcgtggcttt cccggtaacc
     7021 cttcgtaagg cgtggatgag gtggcaatat cgccttacaa agccacttcg gtgcgacggg
     7081 cggaggcttt gcgcgccggc cggtttgccg taaggtgccg tcatcgactt tctcctgcgg
     7141 cgcaggcctc ttcgcgatgg ccggtgccgc gcatcgctgt catgagtgat tcaccggttt
     7201 ccccttgtct gggtccttgg ctgccgaacc cgggcaggtt ttcgggcgtg cgcacctcca
     7261 tcgtatgtgg cgcgctcctg gtttgtacgc ttgcgccttc ggaggcaagc gcgcagttgc
     7321 gcttcatcgt cggcggtgag gagcaggcgc agcgcttccg cccggccggt gccggggagc
     7381 gtcccgagtg gcgcgacacg ctgagcgaac agcacaagga tcgcgacggc gcgcgcgagc
     7441 gccggcggat gagcgacgaa gagcgcagcg acctgcgtcg ccacatgcgc gacgccgccc
     7501 gcggcgccta ccgcgaggag ccgggccgca agccgcagcg ctgagcggtc atgtccgcgc
     7561 gcctgcgggc gcgaacaagg cggtgagctc agcgcggcac gtatcggaac cgctgcattc
     7621 gccgtggcaa ccgcttctgt atgggcccat cggcgtacga aacggcgctc cgtgggtaga
     7681 atggcggccc catgaacatc ctctccatcg aaaccgccac cgagcacggc agcgtcgcgt
     7741 tgctgcatgg cgacgagttg ctggtccggc gcatccaggg cgcggccaat cattccgagg
     7801 cggtgctgcg cgacctgcgc gaactcctcg ccgaggctgg gctcgccgtc gcgcagctcg
     7861 acgccgtcgc ctttggtgcc gggcccgggg cctttaccgg actgcgcctc gcctgcggcg
     7921 tcgcccaggg tgtcgcgctc gccgcggatc ttggcgtggc cgcagtcggc agcctgcagg
     7981 cgctcgcgct ccaggtgggc gcaccgcggg ttctcgcggc aaccgatgct cgcatggggg
     8041 agatctactg cgcgaccttt gtctgcgatg gcgaaggggt gccgcgcctg cagggcacgc
     8101 tgcgctgctg cgcaccgctc gacctcgaac tgccgcccgg cgagtggagc gcggccgggt
     8161 ccgccttccg tgcctggccg gaggagctcg aggcaaggac cgccgggcgc ctcgtcgcct
     8221 gccagcccga cctgtacccg cgcgccgaag aggtcgcccg cctcggtgcc atccaggcgc
     8281 gcgacgctgt gctggtggcg cccgaactgg ccgcgccgct ctatgtgcgc gacaaggtcg
     8341 ccctcaccac cgccgagcgt cgcgcgcgcg gggggcgcgc ctgatgcagg cgctcgcctt
     8401 cgcgccgatg cgcgaggagg acctcgactg ggtcagcgcg cgcgaggcgg agctccacgc
     8461 ccacccctgg tcgcgcggca actttgcgga ctcgctcgcc agcggctacg acgcgtgggt
     8521 cctcacgtgc gatggcgtgt ctgccggcta cgcgatcgtg atgaacgtgc tcgacgaggc
     8581 ccacctgctc gacatcggca tcgtcgccgc gctgcagggc aggggcctgg ccatgcgctt
     8641 ccttgactgg ctggccgagg gcgcaaaggc gcgcggcgcc tgcgacttct acctcgaggt
     8701 gcggccctcg aacgccgccg cgctacgcct ctatgcgcgc agcggtttcg tcgagatcgg
     8761 tcgccggcgt ggctattacc ccgccgccga cgggcgcgag gatgcgatcg tgatgaggcg
     8821 cacgctgtga gcgcgccgcg cctgtcttcc cgccgcgacg cggtgctgcg cgagatgggc
     8881 ctgggtccga tctggcgcct gcgcgcgcgg aaggcggagg cggacgtgac ggaggattcc
     8941 gcgccggaag acagcgcgcc tgcgtggacc gggactgcag cggcgatcgc gacgccacgc
     9001 gccgaggcgc cacccacgcc gatggcacgc tccgtcgaac ctgagccggc cgccgggccg
     9061 cagccgaggc cggcgcaccc ggccgcgccg cgcaacgccg agccgccacg gatccacgcc
     9121 gctcgccccc agcccccggc cacccccacg cctgcagcca cgctcgctgc gcctgcagcg
     9181 ccggacccgg cgcgcagcgc ccgcatcgcc accctcgact gggacgccct cgaagccggg
     9241 atccgcgact gcaaggcctg cgttctgtgc gagcgccgca agcaggccgt gcccggcgtc
     9301 ggcgaccgcc aggcacgctg gatgctggtg ggcgagggcc cgggcgcgga ggaggaccag
     9361 cgcggcgagc ccttcgtcgg ccaggccggg cgcctgctcg acaacatgct ggcggcgatc
     9421 gggttgaagc gtggcgagga cgtctacatc gccaacgccg tcaagtgccg gccaccgcac
     9481 aaccgcaccc cggagcgcgg cgagatcgcc gcctgcctgc cctacctcga ccgccagatc
     9541 gcgctcgtgc agccgcaact cctgatcgcg ctcggccgtc cggccgcgca ggcgctgctc
     9601 gatcgcgaga tcgcgatctc ggcggcgcgc ggcaagcgct tcgagcgcgc gggcgttgcg
     9661 gtcgtggtca cctaccaccc ggcctatctg ctgcgcaatc cgcaggacaa ggccaaggcc
     9721 tgggaagacc tctgcttcgc gcgccggctg atggccggga caggttgagg gcggaggggc
     9781 gaacggaggg aagggcgcag atcggcggtg gagccggcgt gcgggggcgt cgcctccgca
     9841 cggccggtcc tcagtgcagc cgatcctcga gcagcgcgac gttgtcgaac tcgcgctggt
     9901 tggcgtcgtg gcgacgcttg accagcagca tggtgccggc gacgaagagg ccgaacatca
     9961 cgatcacggt gttgatcgac aggccgagca cgatcagcag cgcataggtt ccggtcatca
    10021 ccaggatcga caggttctcg ttgaagttct gcaccgcgat cgagtgcccc gcgcccatca
    10081 ggatgtggcc gcggtgctgc agcagggcgt tcatcggcac cacgaagaag ccggccaggc
    10141 cgcccacgat caccatcagc accatcgcga tccaggcctc ggtgacgccc accatggtca
    10201 tcaccccgag gcccatcgcg atgccgagcg ggatcacgtt caccgcgcgc cgcagcgtga
    10261 tgtagcgtgc cgccagcacc gagccggtgg ccacgccgag cgccaccacg ccctgcagca
    10321 tcgaggcctg cgacaggttc atgccgaggt tgtgctccgc ccacttgatc acgatgaact
    10381 gcagcgtcgc gccggcaccc cagaacagcg tggtgaccgc aagcgagatc tgcccgagct
    10441 tgtcacgcca gagcaggcgc aggcagtggt tgaagtcgtg cagcaggtag agcgggttgc
    10501 tcttgagcgg cttgtggtcc accccggtgt ccgggatgta catgttgaag atggccgcca
    10561 ccaggtacag ggtaccgacc atcagcaccg cagccccgaa ggccgagccg acgccgggca
    10621 ggcccagccc catcagccag gtggagacgt cgccccggat catgatgccg ccgaccacgg
    10681 taccgacgat gatcgccgcc acggtgaggc cctcgatcca gccgttggcc accaccagca
    10741 ggcggtgggg gaggtactcg gtgaggatgc cgtacttggc cggcgagtag gctgccgcgc
    10801 cgaggccgat caccgcgtag gcgaacagcg gatgcgtacc caggaagagc atcaggcagc
    10861 cgccgatctt gatcgtgttg ctgatcagca tcacccgcca cttgggcatc gagtcggcga
    10921 aggcgccgac gaaggcggcg agcgcgacgt aggagacagt gaagaagagc ttgagcagtg
    10981 gctcgtattc ggagggggcc gccatgtccc gaagcatggc gatggcgatg atcagcaagg
    11041 cattgtcggc cagcgcggag aagaactgcg ctgccatgat gatgtagaag ccgagcggca
    11101 tcgtcgggtc gcggcggaag gtcgaagcgc ggtttatatc acgaagcgga ttgccccgtg
    11161 atgatctcgc tcagcgcatg tgcgggggcg cgcaaacgcc cgtatggcaa cggtttgcgc
    11221 cggcagcgga gcgggcctcg cgacgaacgc gccgtgatcc acccgaatgc gctggattgt
    11281 gctttaatcc acttatataa atcgtactta ttcacaccat ggcagatcgc agactccagg
    11341 tattccacgc ggttgcgaag cacggctcct tcacgcgtgc cgcggaacac ctccacatga
    11401 cgcaaccggc agtcaccttc cagatcaagc agctcgagga gcacttcgac acccgcctgc
    11461 tcgatcgcgg tcacggcaag atcacgctca ccgccgcggg cgagctcgtg ctcgcctacg
    11521 ccgagcgcat cctgggcctc tcggccgagc tcgactcgcg cgtctccgag ctcaccgacg
    11581 agctcgccgg ccagctgcgc atcggcacca gcaccacgat cgccgcctac tggctgcctc
    11641 aggtgctgga gagcttcaag cgccgctacc ccggcgtgct gccgcgggtc gtggtcggca
    11701 cctccaagct caccgaggac cgcgtggccg cgcgcgacct cgacctcggc ctcatcgaga
    11761 tcgccaccga gcagcccagc atcgagcgcc gcagcgccgc gagcgacgac ctgctggtg
//
LOCUS       DAOTIN010000102        11774 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_6492_length_11774_cov_9.584436, whole genome shotgun sequence.
ACCESSION   DAOTIN010000102 DAOTIN010000000
VERSION     DAOTIN010000102.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 11774)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 11774)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11774
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6492_length_11774_cov_9.584436"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(67..306)
                     /locus_tag="P5537_13090"
     CDS             complement(67..306)
                     /locus_tag="P5537_13090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin family protein"
                     /protein_id="HRV79019.1"
                     /translation="MSREWCHLCHDLVDALRPLADAAGWDIEVIDVDQHPDLEARWGE
                     WVPVLLHGQHELCHYRLDEAAVRAYLSGFPLESRA"
     gene            complement(339..1793)
                     /locus_tag="P5537_13095"
     CDS             complement(339..1793)
                     /locus_tag="P5537_13095"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Do family serine endopeptidase"
                     /protein_id="HRV79020.1"
                     /translation="MNLDLRLRAACPGAFVLLVCLLLMLVAPPSRATDAVTLPDFTRL
                     VATQGAAVVNISATQAPERPQKQPFRLPELDESDPMFEFFRKFIPRMPEYPGAEPDDK
                     SLGSGFIISPDGYILTNAHVVEAAESIVVRLADKREFDATVIGADARSDVALIRIDAT
                     ALPHVVLGDPEALAVGEWVLAIGSPFGFEQSVTAGIVSAKGRSLPDENFVPFIQTDVA
                     INPGNSGGPLFNLRGEVVGINSQIYSRTGGFMGLSFAIPIDVAMDVQQQLREKGRVER
                     GRIGVSIQEITRDLADSFRLPRPAGALVSSVEAGGPAAVGGIVQGDVIVRFNDRAVEN
                     SADLPRIVAAARPGSRVEVEIYRDGTPRSLSVTLGEWRDPEEEIEPAALGSAAGVTNR
                     LGLELAAPTAQQRRERSIAHGLLVQRAEGPAARAEIVAGDLVLAIVAEGRQVKLDRVE
                     DFEHAVAALKPGQQVTVLVGRGEASSYVSLRAEK"
     gene            complement(1790..2260)
                     /locus_tag="P5537_13100"
     CDS             complement(1790..2260)
                     /locus_tag="P5537_13100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004336969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR reducing system RseC family protein"
                     /protein_id="HRV79021.1"
                     /translation="MMEARARILRIENGQAWVKLSGKQGGCGRCDEPGGCGSVQISHA
                     FGMPRDEFAMPVDSRFAVGDAVVIRIPDGAPLRAALVSYGLGTLLLLVGAALGSLAGG
                     ADRGDAWGLAGAVAGLALAWGVNRLLPRSRNWRNSLSMELSVEEDCSRRLRVLQ"
     gene            complement(2257..3225)
                     /locus_tag="P5537_13105"
     CDS             complement(2257..3225)
                     /locus_tag="P5537_13105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002930020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucB/RseB C-terminal domain-containing protein"
                     /protein_id="HRV79022.1"
                     /translation="MRLFSVMLGFCALLAQGPAFAEHPTDPLSWLGRISTAGQRLNYV
                     GTFVYQSGSHVETSRIAHRVDASGEYERLEVLDGSPREIIRRGAEVRCVLPDERTVII
                     DEAQGRRAFPARLPVSPTGLAESYRVRKGELGRVAGLEAQALVLEPKDELRYGHVLWA
                     DLQTGLLLKSRTLDQHGGLIEQFSFSEVRIGGDVDDSLLESRFETGEGWRTLNARGSS
                     MPVEAAGWVLEPAVPGYTLTSVMKRPLGRERGEAVHMVFSDGLAAISVFIEPVGEGSK
                     AGLGPLSSGAINIFKRAIGGHLVTALGEAPEAAVRRVGESIRPEVR"
     gene            complement(3222..3761)
                     /locus_tag="P5537_13110"
     CDS             complement(3222..3761)
                     /locus_tag="P5537_13110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E factor negative regulatory protein"
                     /protein_id="HRV79023.1"
                     /translation="MKDKVSALFDGDLDDQGMRAVFDGMRKDASLRREWDTYCLIGDT
                     LRGDAAGSGDFVSRVMASLDDEPTLLAPRAQPAAVTQRGLVHRLMPLAASVMGVAAVG
                     LVAASLYRQDAPAPQMAVAASPIQLVNSPNVRPVVAPAADPMREYLFAHQGLTRGGPM
                     PAGVQYVRTVSDTREGGAR"
     gene            complement(3770..4369)
                     /gene="rpoE"
                     /locus_tag="P5537_13115"
     CDS             complement(3770..4369)
                     /gene="rpoE"
                     /locus_tag="P5537_13115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011765363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoE"
                     /protein_id="HRV79024.1"
                     /translation="MSDRELDQQLVERVQRGDKQAFGLLVSKYQRKLNRLLSRLIRDP
                     AEVEDVAQETFIKAYRALGSFRGDSAFYTWLYRIGINTAKNYLVSQGRRAPTSTSFDS
                     EEAETFEDGDQLRDINTPERLMMTRQIGETVEDAMAALPEELRTAIMLRELEGLSYEE
                     IAGIMECPIGTVRSRIFRAREAIAERLRPLLDTAPDKRW"
     gene            4595..6193
                     /gene="nadB"
                     /locus_tag="P5537_13120"
     CDS             4595..6193
                     /gene="nadB"
                     /locus_tag="P5537_13120"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002930027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008734 - L-aspartate oxidase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HRV79025.1"
                     /translation="MLKQYDVLILGSGTAGQSMALRLADRLRVALVTKRELADSASNW
                     AQGGIAAVLDNTDSIEAHIQDTFVAGAGLCNPQSTRFVVENGKRAIEWLIDRGVPFTR
                     EADSQLGYHLTREGGHSHRRIIHAADATGAAVQATLGDHVRRHPNIDIFEHHIAVDLI
                     TGDKLGQPGAGCLGAYVLDIEGERVLTFAARNTVIATGGTGKVYLYTTNPDVATGDGV
                     AMAWRAGCRVGNMEFIQFHPTCLYHPQAKSFLISEAVRGEGGLLKLPDGTRFMPDHDP
                     REELAPRDIVARAIDFEMKKRGIDCVYLDISHKPADWLRGHFPNIHARCLELGIDITK
                     EPIPVVPAAHYSCGGIMTDLAARTDVPGLYAVGESACTGLHGANRLASNSLLECLVFG
                     EAAAEDILSKENTPAPVLPDWDESRVTDADEEVVISHNWAELRRFMWDYVGIVRTNKR
                     LRRAQHRIRLLSREIHEFYSNFRVSNDLIELRNLVTTADLIVRCALKRKESRGLHHSR
                     DFPETLPKARDTVLRPQAPRPRKG"
     gene            complement(6253..6750)
                     /locus_tag="P5537_13125"
     CDS             complement(6253..6750)
                     /locus_tag="P5537_13125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79026.1"
                     /translation="MRFPIELKLRGSSTIKASVWVVHVAAALALFHVPAFREWGGGGV
                     DGLIAAGAWGSLLVSLLRGLRTQAGLEGCTVWLEGDGALELSREPGGTGGLYRVRADS
                     RVVLPMAAWFALDPVAQSAADAEASRVRRLFLVPDNLSAGSFRLLRVWLRHRAGRVPP
                     GNTAP"
     gene            complement(6773..8008)
                     /gene="fabF"
                     /locus_tag="P5537_13130"
     CDS             complement(6773..8008)
                     /gene="fabF"
                     /locus_tag="P5537_13130"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HRV79027.1"
                     /translation="MSRRRVVVTGLGVISPVGNTVTEAWSNLIAGKSGIGPITRFDAS
                     NFASRIAGEVKDFDVSAYLSPKEARRMDVFIHYGMAAGIQAIRDSGIEVTEANADRIG
                     INIGSGIGGLPMIEDTHNDFLGGGPRKISPFFIPGTIINMISGNLSIMFGMKGPNLAV
                     VTACTTGLHAIGMGARMIGYGDADVMVCGGAESTVTNLAIGGFGSAKALSTRNDDPAT
                     ASRPWDKGRDGFVLGEGAGVMVLEEYEHAKRRGARIYAEIAGFGMSGDAYHMTAPDTD
                     GPRRSMVNAMKDAGVSVDQVHYLNAHGTSTPLGDKNETDAIKLAFGVDAAKKLVVNST
                     KSMTGHLLGGAGGLESVITALAVHHQISPPTINLFEQDPECDLDYCANVAREMKIDVA
                     LKNNFGFGGTNGTLVFRRV"
     gene            complement(8107..8346)
                     /gene="acpP"
                     /locus_tag="P5537_13135"
     CDS             complement(8107..8346)
                     /gene="acpP"
                     /locus_tag="P5537_13135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011238908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HRV79028.1"
                     /translation="MENIEQRVKKIVAEQLGVNESEIKTESSFVDDLGADSLDTVELV
                     MALEEEFECEIPDEEAEKITTVQQAIDYVNAHLKK"
     gene            complement(8435..9184)
                     /gene="fabG"
                     /locus_tag="P5537_13140"
     CDS             complement(8435..9184)
                     /gene="fabG"
                     /locus_tag="P5537_13140"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase FabG"
                     /protein_id="HRV79029.1"
                     /translation="MSFSLEGQVALVTGASRGIGRAVALELGRLGATVVGTATSESGA
                     ADIGKALADAGIQGAGMALNVTDAAACEALLGEVEKRFGAVGILVNNAGITRDNLAMR
                     MKDEDWDAVLDTNLRAVFRMSKLVMRGMMKARNGRIINITSVVASSGNPGQANYAAAK
                     AGVAGMTRALARELGSRNITVNCVAPGFIDTDMTRALPEAARDALLGNIALGRLGRPE
                     EIAGAVAFLASPAAAYVTGTTLHVNGGMYMS"
     gene            complement(9188..10117)
                     /gene="fabD"
                     /locus_tag="P5537_13145"
     CDS             complement(9188..10117)
                     /gene="fabD"
                     /locus_tag="P5537_13145"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011765357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HRV79030.1"
                     /translation="MAFALVFPGQGSQSVGMMAAYGESAVIRDTFAEASEALGEDLWA
                     MVCDGPAERLALTVNTQPLMLTAGVAAWRAWLAAGGPKPAVVAGHSLGEYSALVAAGA
                     MAFKDAVPLVRFRAQAMQEAVPAGEGAMAAVMGLEPDAVHAACAEAAQGEVVEAANLN
                     APGQIVIAGAKAAVERASEIAKAKGAKRAVLLPVSAPFHCALMRPAAERLTERLAGVS
                     IVKPEIDVINNVDVAVYDDPEKIRDALVRQAYSPVRWIELVQAMAARGMSHVIECGPG
                     KVLAGMTKRIAKEVEGGSAHDAASLEQAIAAVR"
     gene            complement(10164..11129)
                     /locus_tag="P5537_13150"
     CDS             complement(10164..11129)
                     /locus_tag="P5537_13150"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011238905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HRV79031.1"
                     /translation="MIYARIAGTGSYLPGEPVSNDDLVKRGIETSDEWIVSRSGIRSR
                     HLAAADTGASDLARVAAERAIEAAGCEAEDIDLIIVATSTPDYIFPSTAALVQSKLGI
                     RNGGAAFDVQAVCSGFIYALSVAEKFIRSGSHKRALVIGAEVFSRILDWSDRATCVLF
                     GDGAGAVVLEASEHPGILASALHADGSHHPILCVPGGVASGQVIGDPFLRMDGQAVFK
                     FAVKVLGDVANEVLDAAGVEASSIDWLIPHQANIRIIQATAKRLGVPMERVVTTLDHH
                     GNTSAASIPLALDEAVRTGQLRPGHRIVVEGVGGGFTWGAALIDF"
     gene            complement(11126..>11774)
                     /gene="plsX"
                     /locus_tag="P5537_13155"
     CDS             complement(11126..>11774)
                     /gene="plsX"
                     /locus_tag="P5537_13155"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HRV79032.1"
                     /translation="IDRPAIATVLPSMKGHTYVLDLGANVDCSAEHLLQFGVMGAMLV
                     AAIEHKDRPSVGLLNIGEEVIKGNDVVKEAGDLLRNSGLNFHGNVEGNDIYEGTVDVV
                     VCDGFVGNVALKTSEGLAQMVGAFLKQEFKRTLFTKLLAVAAMPVLKRFKKRVDHRLY
                     NGAPLLGLRGVVLKSHGSADVLAFGNALSRAAEAASNRLIERISERMASMNEVNA"
BASE COUNT         1955 a         4119 c         3835 g         1865 t
ORIGIN      
        1 aggtgccttt cagcacccgt ttcggaaagg attcggttgg tcgctggccg ggttcggtcc
       61 agcgcgtcag gcccgcgatt ctagcggaaa accgctcaga taagcgcgta cggcggcctc
      121 gtcgaggcga tagtggcaaa gttcgtgctg gccgtgcagc agcaccggga cccactcgcc
      181 ccagcgcgcc tcgagatccg ggtgctggtc gacgtcgatg acctcgatgt cccagccggc
      241 cgcatcggcc agcgggcgca aggcgtccac gagatcgtgg cacaggtggc accactcccg
      301 gctcattacg gtgaagcgct gttccactgc cggaccgctc acttttcggc gcgcaggctg
      361 acgtaggacg aggcctcgcc gcgcccgacc agcacggtga cctgctgccc gggcttgagc
      421 gccgcgaccg cgtgctcgaa gtcctcgacc cgatcgagct tgacctggcg gccttccgcg
      481 acgatcgcca gcacgagatc gccggcgacg atctcggcac gcgccgccgg cccctccgcg
      541 cgctgcacga gcaggccgtg ggcgatcgag cgctcgcgcc gctgctgtgc agtgggcgcg
      601 gcaagttcga ggccgaggcg attggtaacc cccgcagccg agccgagcgc cgcgggctcg
      661 atctcctcct ccgggtcgcg ccactcgccg agcgtcacgc tcagcgaacg cggcgtaccg
      721 tcgcggtaga tctcgacctc gaccctgctg ccgggacgtg ccgccgcgac gatgcgcggc
      781 agatcggcgg agttctccac ggcgcgatcg ttgaagcgca cgatcacgtc gccctgcacg
      841 atgccgccga ccgcagccgg cccgcccgcc tcgacgctgc tcaccagcgc gcccgccgga
      901 cgcggcaggc ggaagctgtc ggcgaggtcg cgggtgatct cctggatgga gacgccgatg
      961 cgcccgcgct ctaccctgcc cttctcgcgc agttgctgct ggacgtccat cgccacgtcg
     1021 atcgggatcg cgaaagacag gcccatgaag ccgccggtgc ggctgtagat ctgcgagttg
     1081 atgccgacca cctcgccgcg caggttgaac agcggcccgc cggagttccc cgggttgatc
     1141 gccacgtcgg tctggatgaa gggcacgaag ttctcgtcgg gcaggctgcg ccccttggcg
     1201 ctgacgatgc cggcggtcac cgactgctcg aagccgaagg gcgagccgat cgcgagtacc
     1261 cattcgccta ccgcgagcgc ctcggggtcg ccgagcacga cgtgcggcag cgccgtggca
     1321 tcgatccgga tcagcgcgac gtcgctgcgc gcgtcggcac cgatcaccgt ggcgtcgaac
     1381 tcgcgcttgt cggcgagacg cacaacgatg ctctcggcgg cctcgaccac atgcgcgttg
     1441 gtgaggatgt agccgtcggg gctgatgatg aagccggatc ccagcgactt gtcgtcgggc
     1501 tccgcgcccg ggtactcggg catgcgcgga atgaacttgc ggaagaactc gaacatcgga
     1561 tccgattcgt cgagttcggg cagacggaag ggctgcttct gcggcctttc cggtgcctgg
     1621 gtcgcactga tgttaaccac cgcggcacct tgcgtcgcca ccaggcgggt gaagtccggc
     1681 agcgtcaccg cgtcggtcgc ccggctcggc ggcgcgacca gcatcagcag cagacacacc
     1741 agcaagacga acgcgcccgg gcaagccgcg cgcaggcgaa ggtcgaggtt cattgcagga
     1801 cgcgcagccg gcggctgcaa tcctcctcga ccgagagttc catgctcagg ctgttgcgcc
     1861 agttgcggct gcgcggcaga aggcggttga ctccccatgc gagcgcgagt cccgcgaccg
     1921 ccccggccag accccaggcg tccccgcgat ccgcgccgcc cgcgaggctg ccgagcgccg
     1981 cacccaccag gaggagcagt gtgccgaggc cgtagctgac cagcgccgcc cgcaagggcg
     2041 cgccgtccgg gatgcggatc accacggcgt cgcccacggc aaatcgggaa tcgaccggca
     2101 tcgcgaattc gtccctgggc atcccgaagg catgcgagat ctgcaccgaa ccgcaaccgc
     2161 caggttcatc gcagcgtccg cagccgccct gctttccgct gagcttgacc caggcctggc
     2221 cgttctcgat gcgcaggatg cgggcgcgcg cttccatcat cggacctccg gccggatgct
     2281 ctcgccgaca cgacgcaccg cagcctccgg cgcctcgccg agcgcggtga ccagatggcc
     2341 gccgatcgcg cgcttgaaga tgttgattgc tccgctcgag agcggaccga ggccggcctt
     2401 cgaaccctcg cccaccggct cgatgaacac cgagatcgcc gccagcccgt cgctaaacac
     2461 catatgtacc gcctcgccac gttcgcggcc cagcggacgc ttcatcaccg aggtgagcgt
     2521 gtatccggga accgccggct ccagcaccca gcctgcagcc tcgacgggca tgctgctgcc
     2581 acgggcgttg agcgttcgcc agccttcgcc ggtttcgaag cgagattcga gcagcgagtc
     2641 gtccacgtca ccgccgatgc gcacctcgct gaagctgaac tgctctatga ggccaccgtg
     2701 ctggtccagc gtgcgcgatt tgagcagcag gcccgtttgc aggtcggccc aaagcacatg
     2761 cccgtaacgg agctcgtcct tgggttcgag caccagggcc tgcgcctcca gcccggccac
     2821 ccggcccaac tcgcccttgc gcacccggta gctctcggcc aacccggtcg gcgacaccgg
     2881 aaggcgcgcc gggaaggccc gccggccttg ggcctcgtcg atgatcaccg tgcgctcgtc
     2941 gggcagcacg caacgcacct ccgcgccgcg acggatgatt tcgcgcgggc tgccgtcgag
     3001 cacctcgagg cgttcatact cgccgctggc gtcaacccga tgggcgatgc gcgaggtctc
     3061 gacgtggctg ccggactgat agacgaaggt gccgacgtaa ttgagacgct gccccgcggt
     3121 ggagatgcgc ccaagccagg acaggggatc cgtcggatgc tcggcgaacg ccggaccctg
     3181 cgcgagcagc gcgcagaatc cgagcatgac ggagaacaac ctcatcgagc cccgccctcg
     3241 cgcgtatcgg acaccgtacg gacatactgc actccggccg gcatcgggcc gccgcgggtg
     3301 aggccctggt gggcgaatag gtactcacgc atcggatcgg cggcgggcgc gacgaccgga
     3361 cgcacgtttg gcgaattcac cagctggatc ggcgatgcgg cgaccgccat ctgcggtgca
     3421 ggcgcatcct gcctgtacag gctcgccgcc accagcccca ccgccgccac gcccatcacc
     3481 gaggccgcga gcggcatcag gcgatgcacc agcccgcgct gcgtcacggc tgccggctga
     3541 gcacgcggcg caagcagcgt gggctcgtcg tccagactcg ccatgacgcg ggagacgaaa
     3601 tcgccggaac cggcagcgtc accgcgcagg gtgtcaccga tcaggcaata ggtgtcccac
     3661 tccctgcgca acgaggcatc cttgcgcatg ccgtcgaaca ccgcacgcat cccctggtcg
     3721 tcgagatctc cgtcgaacag cgccgacact ttgtccttca tgcttgcacc taccaacgtt
     3781 tgtccggggc cgtgtccagc aggggccgca gacgttcggc tatcgcttcg cgcgcacgga
     3841 agatccgcga gcgcaccgtc ccaatcgggc attccatgat cccggcgatc tcctcgtagc
     3901 tgagcccttc gagctcgcgg agcatgatcg ccgtcctcag ttcctcgggc agtgcggcca
     3961 tcgcgtcctc cacggtctcg ccgatctggc gcgtcatcat cagccgttcc ggcgtgttga
     4021 tgtcgcgcaa ctgatcgccg tcctcgaagg tctccgcctc ctccgagtcg aaactcgtcg
     4081 aagtcggggc cctgcggccc tgtgagacca ggtagttctt tgccgtgttg atgccgatgc
     4141 ggtaaagcca ggtgtagaac gcactgtcac cccgaaacga acccagcgct cgataagcct
     4201 tgatgaaggt ttcttgcgcc acgtcctcaa cttccgccgg gtcgcggatc agcctcgaca
     4261 gcagtcgatt cagcttgcgc tggtacttgg ataccagcag accgaatgcc tgcttgtcgc
     4321 cgcgctgaac acgctcgacg agttgctgat cgagttcccg atcgctcatg ggttcctgtt
     4381 gattccgggg aattcaaaaa ttcgaagatc ccggattata agcgagcggg acaatccatc
     4441 agcagaaatc gaagacactg gaactgacag ggtcgggtgg aaatagttca ggcatgagga
     4501 gcttcgtcgc cagggcccga cgatccgcgc gcgcccggcg gcctgtcacc gcatgctata
     4561 tttccttccc cgcaaatccc gcccgagcga catcttgctg aaacagtacg acgtactcat
     4621 tcttggcagc ggcaccgccg gccagtcgat ggccctccgc ctggcggacc gcctgcgtgt
     4681 ggcgctcgtg accaagcgcg aactcgcaga cagcgcgagc aactgggcgc agggcggcat
     4741 cgccgcggtg ctcgacaaca cggacagcat cgaagcccac atccaggaca ccttcgtcgc
     4801 cggtgcaggc ctttgcaacc cgcaatcgac acgcttcgtg gtcgagaacg gcaagcgcgc
     4861 gatcgagtgg ctgatcgacc gcggcgtgcc cttcacccgc gaagccgact cccagctcgg
     4921 ctaccacctc acccgcgaag gcggccactc gcatcgacgc atcatccatg cggccgacgc
     4981 aaccggcgcc gcggtgcagg ccacgctcgg cgaccatgtg cgccggcacc cgaacatcga
     5041 catcttcgag caccacatcg cggtcgacct gatcaccggt gacaagctcg gccagccggg
     5101 cgcaggctgc cttggcgcct acgtgctcga catcgagggc gagcgcgtgc tcaccttcgc
     5161 cgcgcgcaac accgtgatcg caaccggcgg aacgggcaag gtgtacctgt atacgaccaa
     5221 ccccgacgtc gccaccggcg acggcgtcgc gatggcctgg cgtgccggtt gccgcgtggg
     5281 caacatggag ttcatccagt tccaccccac ctgcctctac cacccgcagg ccaagtcctt
     5341 cctgatctcc gaggcggtgc gcggcgaggg cgggctgctc aagctgcccg acggcacccg
     5401 cttcatgccc gatcacgacc cgcgcgagga gctcgccccg cgcgacatcg tcgcgcgcgc
     5461 gatcgacttc gagatgaaga agcgcggcat cgactgcgtg tacctggaca tcagccacaa
     5521 acccgccgac tggctgcgcg gccacttccc caacatccac gcccgttgtc tcgagctcgg
     5581 catcgacatc acgaaggaac cgatcccggt cgtaccggcg gcgcactatt cctgcggcgg
     5641 catcatgacc gacctcgccg cgcgcaccga cgttcccggg ctctacgccg tgggcgagtc
     5701 ggcgtgcacc ggactgcacg gcgccaaccg cctggcgagc aactcgctgc tcgagtgcct
     5761 ggtcttcggc gaggctgccg cggaggacat cctctccaag gagaacacgc ctgcgccggt
     5821 gctgcccgac tgggacgaga gccgcgtcac cgacgccgac gaggaggtgg tgatctcgca
     5881 caactgggcg gagctgcgtc gcttcatgtg ggactacgtc ggcatcgtgc gcaccaacaa
     5941 gcgcctgcgt cgcgcccagc accgcatccg cctgctgtcg cgcgagatcc acgagttcta
     6001 ttcgaacttc cgcgtcagca acgatctgat cgagctgcgc aacctggtga ccaccgccga
     6061 cctgatcgtg cgctgcgcgc tcaagcgcaa ggagagccgt ggactccacc actcgcgcga
     6121 ctttcccgag accctgccga aggcgcgcga caccgtcctt cgcccgcaag caccccggcc
     6181 ccgcaagggc tgaacagccg cgcaggccct gccctgccct gccctgacgc gggccgtcgc
     6241 agtgcggtcg cttcagggcg cggtgttccc tggcggcacg cgcccggcac ggtggcgcaa
     6301 ccagaccctg agcagtcgaa agctgcctgc cgacagattg tcgggtacga ggaacagtct
     6361 tcgcacgcgc gatgcttcag cgtcggccgc tgactgcgcc accggatcca gcgcgaacca
     6421 cgccgccatc ggcaacacca cccgcgaatc cgcgcgcacc cggtacaggc caccggttcc
     6481 tccgggctcc ctcgacaact cgagtgcgcc atcgccctcc agccacaccg tgcagccttc
     6541 cagaccggcc tgcgtgcgca ggccgcgcaa cagcgacacc agcagcgaac cccaggcgcc
     6601 agcggcgatc agcccatcca cgcctccgcc tccccactcg cggaaagccg ggacatgaaa
     6661 aagcgccagt gcggccgcga catgcacgac ccacaccgac gcttttattg tgctcgagcc
     6721 gcgcagcttc agttcgatcg ggaaccgcat gccgcgccgc cgcgcagacg gatcagaccc
     6781 ggcggaagac cagggtgccg ttggttccgc cgaagccgaa gttgttcttc agggccacat
     6841 cgatcttcat ctcgcgagcg acgttggcgc agtagtccag gtcacactcg ggatcctgct
     6901 cgaagagatt gatcgtcggt ggcgagatct ggtgatgcac cgcgagggcg gtaatcaccg
     6961 actccagacc gccggcgcca ccgagcaggt ggccggtcat cgacttcgtc gagttcacca
     7021 ccagcttctt cgcggcatcc acgccgaagg cgagcttgat cgcgtcggtc tcgttcttgt
     7081 cgccgagcgg ggtcgaggtg ccgtgcgcgt tgaggtagtg cacctgatcg acgctgacgc
     7141 cggcatcctt catggcgttg accatgctgc ggcgcggacc gtcggtgtcg ggtgcggtca
     7201 tgtggtaggc gtcgccgctc atgccgaagc cggcaatctc ggcgtagatc ctggcgccac
     7261 ggcgcttggc gtgctcgtac tcctcgagca ccatcacgcc ggcgccctcg ccgagaacga
     7321 agccgtcacg ccccttgtcc cacggacggc tggcggtggc gggatcgtcg ttgcgggtcg
     7381 acagcgcctt ggcggagccg aagccgccga tggcaaggtt ggtcacggtg gactcggcgc
     7441 cgccgcacac catcacgtcc gcgtcaccgt aaccgatcat gcgcgcgccc atgccgatcg
     7501 cgtgcaggcc ggtggtgcag gcggtgacga ccgcgaggtt gggccccttc atgccgaaca
     7561 tgatcgacag gttgcccgag atcatgttga tgatggtgcc cggaatgaag aagggcgaga
     7621 tcttgcgtgg accgccaccg aggaagtcgt tgtgcgtatc ctcgatcatc ggcagtccgc
     7681 cgatgcccga gccgatgttg atgccgatgc ggtcggcgtt ggcctcggtg acctcgatgc
     7741 cggagtcacg gatcgcctgg atgcccgccg ccatgccgta gtggatgaag acatccatgc
     7801 ggcgcgcctc cttgggcgac aggtaggcgg acacgtcgaa atccttcacc tcgccggcga
     7861 tgcgggaagc gaagttgctc gcgtcgaaac gggtgatcgg accgatgccg ctcttgccgg
     7921 cgatcaggtt ggaccaggct tcggtgacag tattgccgac aggcgagatc acgcccagac
     7981 cggtgacgac gactctacga cgcgacacag gcgactccgt tgaaatcgtt ggggaaattc
     8041 agacctgtcc gcttgccgct gcgatgcgcg gtaacgcgga caggggacgc gcagaatgcg
     8101 cgcgggttac ttcttgaggt gggcgttgac gtagtcgatc gcctgctgga cggtggtgat
     8161 cttctcggcc tcttcgtccg ggatctcgca ctcgaactct tcttccagcg ccatgaccag
     8221 ctccacggtg tccagcgaat ccgcgcccag atcatcgacg aacgaagact cggtcttgat
     8281 ctccgattcg ttcacgccaa gttgctcagc gacgatcttc ttgacgcgct gttcgatgtt
     8341 ctccatgaac caactccttc ctgagggtga caggtgaatg taaaaagccg gcgtattcta
     8401 ccaaaacgcc gcagaaccgc tatcccgacg cgaatcagga catgtacatg ccgccattga
     8461 cgtgcagggt ggtgcccgtc acgtaggcgg cagcggggga agcgaggaac gcgacggcgc
     8521 cggcaatttc ttccggacgg ccgaggcgac ccagcgcgat gttgccgagc agggcgtcgc
     8581 gcgcggcctc gggcagcgcg cgcgtcatgt cggtgtcgat gaaaccgggg gcgacgcaat
     8641 tgaccgtgat gttgcggctg ccgagctcgc gcgcgagcgc gcgcgtcatg cctgccacgc
     8701 ccgccttggc cgccgcgtag ttggcctgcc ccgggtttcc ggagctggcc accaccgagg
     8761 tgatgttgat gatgcggccg ttgcgggcct tcatcatgcc gcgcatcacc agcttgctca
     8821 tgcggaagac ggcgcgcagg ttggtgtcca gcaccgcatc ccagtcctcg tccttcatgc
     8881 gcatcgcgag gttgtcgcgg gtgatgccgg cgttgttgac caggatgccg acggcgccga
     8941 agcgcttctc gacctcgccg agcagcgctt cgcaggcggc ggcgtcggtc acgttcagcg
     9001 ccatgccggc accctggatg ccggcgtcgg cgagcgcctt gccgatgtcg gcggcgccgg
     9061 actcggaggt ggcggtgccg accaccgtgg cgccgaggcg gccgagttcg agcgccaccg
     9121 cgcggccgat gccccgcgac gcgccggtga ccagggcgac ctggccttcg agcgagaaac
     9181 tcatgtctta cctcaccgcc gcaatggctt gttccaggct cgccgcgtcg tgcgccgaac
     9241 ccccttcgac ttccttggcg atgcgcttgg tcatgccggc gagcaccttg cccgggccgc
     9301 actcgatgac gtggctcatg ccgcgcgcgg ccatggcctg cacgagctcg atccagcgca
     9361 ccggcgaata ggcctggcgc acgagggcat cacgaatctt ctcgggatca tcgtacaccg
     9421 cgacgtcgac gttgttgatg acgtcgattt ccggcttgac gatgctcacc ccggcgaggc
     9481 gctcggtaag ccgctcggcc gccgggcgca tcaacgcgca gtggaaggga gcggacacgg
     9541 gcagcagcac ggcacgcttg gcacccttgg ccttggcgat ctcgctcgcg cgctccaccg
     9601 ccgccttggc gccggcgatc acgatctggc caggggcgtt gaggttggcc gcctcgacga
     9661 cttcgccctg cgcagcctcg gcgcaggcgg catgcaccgc gtcgggctcc aggcccatca
     9721 ccgcggccat cgccccttcg cccgcaggca cggcctcctg catcgcctgc gcgcggaagc
     9781 gcaccagcgg cacggcgtcc ttgaaggcca tcgcacccgc agcgacgagc gccgagtatt
     9841 cgcccaggct gtgcccggcc accacggccg gcttcggccc acctgcggcc agccaggcgc
     9901 gccacgccgc cacgccggcg gtcagcatca gcggctgggt gttgacggtg agcgcgaggc
     9961 gctcggcggg gccgtcgcag accatcgccc agaggtcctc gccgagcgcc tcggaggctt
    10021 ccgcaaaggt gtcacggatg acggcggact cgccgtaggc ggccatcatg ccgaccgact
    10081 gcgaaccctg gccgggaaaa accagcgcaa acgccatgct gttctccgct tgtatcaaag
    10141 gtgggaaatc ggggaaagga aactcagaaa tcgatcaggg cggcgcccca ggtgaagccg
    10201 ccgccgacgc cctcgaccac gatgcggtgc cccggacgca gttgcccggt acgcaccgcc
    10261 tcgtcgagcg cgagcggaat cgacgccgcc gaggtgttgc cgtggtggtc gagcgtggtg
    10321 accacgcgct ccatcggcac gccgagccgc ttcgcggtcg cctggatgat gcggatgttg
    10381 gcctggtgcg ggatcagcca gtcgatgctg gacgcctcca cgccggctgc atcgagcacc
    10441 tcgttggcga cgtcgccgag caccttgacc gcgaacttga acacggcctg gccatccatg
    10501 cgcaggaagg ggtcgccgat cacctggccg gaggccacgc cgccgggcac gcacaggatg
    10561 gggtgatggc tgccgtccgc gtgcagcgcc gaggcgagga tgccgggatg ctccgaggcc
    10621 tcgagcacga ccgcgcccgc accgtcgccg aacagcacgc aggtggcacg atcggaccag
    10681 tcgaggatgc gcgagaacac ctctgcgccg atcaccagcg cgcgcttgtg gctgcccgag
    10741 cggatgaact tctcggcaac gctgagcgca tagatgaagc cgctgcaaac cgcctgcacg
    10801 tcgaaggccg cgccgccgtt gcggatgccg agcttggact gcaccagggc ggcggtgctg
    10861 ggaaagatgt agtcgggcgt cgaggtggcg acgatgatga ggtcgatgtc ctcggcctcg
    10921 cagccggcgg cctcgatcgc gcgctcggcg gcgacgcggg cgagatcgct cgcgccggtg
    10981 tcggcggcgg ccaggtggcg gctgcggatg cccgagcggc tcacgatcca ctcgtccgac
    11041 gtctcgatgc cgcgcttgac cagatcgtcg ttgctgaccg gctcgcctgg cagatagctg
    11101 cccgtaccgg caatccgtgc gtagatcatg cgttcacctc gttcatgctc gccatgcgtt
    11161 cggagatgcg ctcgatgagc cggttcgacg ccgcctcggc cgcacgcgag agtgcattgc
    11221 cgaaggcgag cacgtcggcc gagccatggc tcttgagcac cacgccgcgc aggccgagca
    11281 gcggcgcacc attgtaaaga cgatgatcga cccgcttctt gaagcgcttg agcacgggca
    11341 tcgccgccac cgccagcaac ttggtgaaca gcgtgcgctt gaactcctgc ttcaggaatg
    11401 ctccgaccat ctgtgccagg ccctcggagg tcttgagcgc gacgttgccg acgaagccgt
    11461 cgcagacgac cacatcgacg gtgccctcgt agatgtcgtt gccctcgacg ttgccgtgga
    11521 agttgagacc gctgttgcgc agcagatccc ccgcctcctt gacgacgtcg ttgcccttga
    11581 tgacctcttc gccgatgttg agcaggccga cgctgggacg atccttgtgc tcgatcgcgg
    11641 caacgagcat ggcgcccatc acgccgaact ggagcaggtg ctcggcgctg caatcgacgt
    11701 tggcgccgag gtcgagcacg taggtgtgcc ccttcatcga cggcagcacg gtggcgatcg
    11761 cggggcggtc gatt
//
LOCUS       DAOTIN010000103        11614 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_6601_length_11614_cov_9.523142, whole genome shotgun sequence.
ACCESSION   DAOTIN010000103 DAOTIN010000000
VERSION     DAOTIN010000103.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 11614)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 11614)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11614
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6601_length_11614_cov_9.523142"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..799
                     /locus_tag="P5537_13160"
     CDS             <1..799
                     /locus_tag="P5537_13160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011764882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="cation acetate symporter"
                     /protein_id="HRV79033.1"
                     /translation="MKRWEKTGLLKFEDKNGDGRIQYYNDKTKSADAKAKAEAAGWKG
                     NELTVNADIMVMANPEIALLPNWVIALVAAGGLAAALSTAAGLLMAISSAVSHDLVKG
                     VFNPNISDKNELLAGKISMAVAIVIAGYLGLNPPGFAAGTVALAFGIAASSLFPAIMM
                     GIFSKKMNKEGAIAGMLAGLFVTLFYVFAHKGIFFVKGTEFIDLIGGANSFFGITPEA
                     FGAVGAIVNFIVAIVVDKVTKEPPEHIQHMVEAVRIPRGSKLVDGAH"
     gene            945..1328
                     /locus_tag="P5537_13165"
     CDS             945..1328
                     /locus_tag="P5537_13165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011764883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79034.1"
                     /translation="MIFNASIALNWILFLALFPIAFFWFRRSWRILFRRDFSEVALKR
                     GMPPADPARFAPYTLAVNLIGGGVIVFVIFGVVAAILDFETWTAIAGVTIWFKFFADY
                     IVSRHAHPIVPRRKKLEEAGQGPKI"
     gene            complement(1368..1628)
                     /locus_tag="P5537_13170"
     CDS             complement(1368..1628)
                     /locus_tag="P5537_13170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4212 domain-containing protein"
                     /protein_id="HRV79035.1"
                     /translation="MELDDRQRAYWRSNLRLTFTLLGVWFGVTFVGGYFASALNTVSF
                     LGFPLGFYLFAQGALLVYLAIIVIYVVAMNRLDRRYRVNSRH"
     gene            complement(1681..3732)
                     /gene="fusA"
                     /locus_tag="P5537_13175"
     CDS             complement(1681..3732)
                     /gene="fusA"
                     /locus_tag="P5537_13175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HRV79036.1"
                     /translation="MTPSSVHDIRNLALFGHAGSGKTTLVEALLAAAGEIGAPGSVER
                     GDTVADFDPQEKAMGHSLHAALVHLEWAGHWINLLDTPGLPDLSGRALVALPAADTAA
                     VVINAAAGIESGTRRMMDAAKGKCRMIVVNKIDAPGADLGALMDAIAATFGRECLPIN
                     LPSADGSRVIDCFFSPDNAAATAFSSPSAAHDAIVDQVVELDEALMAQYLEQGESLDP
                     EQLHAPFEQALREGHLVPVCFVSARSGAGVRELLDILGKLAPDPTEANVPAFLKGEGA
                     AAAAVEVVLDAERHVVAHVFQIANDPYRGKLGLFRVHQGQVTPNSQLYIGDGRKPFKV
                     AHLLRMQGKNTVETALAVPGDLCAVARVDELTRDAVLHDSHDEDYYHLAPAAWPQPVF
                     GLALMTRKPADEQKLSEALARLMEEDPCLEVSFDARHRRTVVRGLGEQHLKIVLDELA
                     ARWNLQLDTATPSIPYRETITVVAEARYRHKKQSGGAGQFGEVALRVEPLPRGAGIEL
                     GDEVKGGTIPTNFMPAVEKGVRQALAEGALAGFPLQDIRVVITDGKHHAVDSNEVSFV
                     TAGRHALIEAVLGARPMVLEPLLDVQVKVADALFGEVSAELAGRRGRLTATDSPAPGW
                     TLISARVPMAALEGFESRLKAICAGESEFVLEAGGHEPAPQDIQAELARVFSSGGNGN
                     H"
     gene            complement(3838..5463)
                     /locus_tag="P5537_13180"
     CDS             complement(3838..5463)
                     /locus_tag="P5537_13180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79037.1"
                     /translation="MLHALYRWIDRNLLELGREMRLSYLPPLMVYCAAGVSGLTGIVG
                     TFFVKDYLGLSAAFLAALGFWAGIPWALKMPIGHLVDLMWRHKAGLVYLGASLIAASL
                     LIMIGLIGSPDAMRAVMPIEAWFVLSVLLSPVGYVMQDAVADAMTVEAVPRVDARGEP
                     IPAETVRLMHTTMQMLGRVAIIGGTVMVSLANVAMFQGSENLPEADKVAIYLRIYELA
                     LIIPLLSVSGVLLGGFLKRREAKRLAALGRSRAEIDRLLHDPEEKTAPNWWILGGSAV
                     FVALTISVGLSGIEYGQEIIFATSFAIIGFMITRLLRELSPEAARTLLGTVIIIFAFR
                     ALPGPGAGASWWMIDELGFDQSFLSRLDLITSALTLAGLFLFRRFMAEKSIAQIVIFL
                     TVATTALSLPIIGMFHGLHEWTAAHTGGVVDARFIAIANTALESPLGQVSMVPMLAWI
                     ANSAPAHLKATFFAVMASFTNLALSASQLGTKYLNQLHTIAREVRDAATGAITTPADY
                     GALGELLVTVTVIALVVPLAAILLTRLAGLRSA"
     gene            complement(5534..6268)
                     /locus_tag="P5537_13185"
     CDS             complement(5534..6268)
                     /locus_tag="P5537_13185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HRV79038.1"
                     /translation="MNPNLEEIWVYLSTSPLLGLTLTLLAYQAAFWIYKRVGFHPLAN
                     PVLISVAILASLLLATGTPYQAYFDGAQFVHFLLGPATVALAIPLHAQWPRLKSMAGP
                     LLIALVAGSLTAALSAWGIGALLGGSRESLMSLAPKSVTTPIAMGVAERIGGLPSLTA
                     VLVISAGIIGAVFGRGVMRRLHVSDHAVHGFAIGIASHGIGTARAFQVSEQAGAFAAL
                     AMGLNGLITAVSLPWIMPWVERLFAG"
     gene            complement(6265..6630)
                     /locus_tag="P5537_13190"
     CDS             complement(6265..6630)
                     /locus_tag="P5537_13190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HRV79039.1"
                     /translation="MIAALTLLLVFQLAGEVIARALALPIPGPVIGMALLFLALLIRG
                     GPGEGLRQTSGQLLQHLSLLFVPAGTGIVIYGDRIAAEWLPLLVALFLSTFLALAVTA
                     LVLKALTHKRAKATTEAAQ"
     gene            complement(6701..7636)
                     /locus_tag="P5537_13195"
     CDS             complement(6701..7636)
                     /locus_tag="P5537_13195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition domain-containing
                     protein"
                     /protein_id="HRV79040.1"
                     /translation="MDQLTRIILEAGRSGVELSLFVLLPIMVVMLSLMRLLEARGVLD
                     WVVARLAPLLRPLGLTGLGVFAALQINLVSFAAPVATLTMMEGRGASDRHLAATLAMV
                     MAMAQANVTFPMAAMGLAFGPALVLSVIGGLAAAAVTYHGFGRGLSAAEAPLDETLHH
                     RVADDAKGVLDVINRAGAEAFKISVGAIPMLVLALVAVMALRASGGIDALTALLAPLL
                     RVFELDPALILLTLTKYIAGGTAMMGVMDEMLKAGTTTVATLNSNAGFLIHPFDVAGV
                     AVLISAGRRVAAVWKPAALGAVVGIAVRAVGHALL"
     gene            complement(7777..8760)
                     /locus_tag="P5537_13200"
     CDS             complement(7777..8760)
                     /locus_tag="P5537_13200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HRV79041.1"
                     /translation="MLAGLSAALGAGLLWGLVFLTPLLLADYPPFMLAIGRYLAFGVL
                     ALGLAWFDRAALARLTRADWIEAVKLALIGNLLYYSTLASAIQLAGGPVPTLIIGTLP
                     VVIAITANLLDRRRGGGEDSAPWARLAAPLALILGGLFAVHSASAQALPADASADYLL
                     GIGFGLFALGCWTWYPIRNSRWLRARGAGLARAWATAQGLATLPVAIVAGVGYWLWDT
                     RLAPGGPGFAWPLGPRPEAFVGMCILLGLAASWLGTLLWNRASHLLPAALVGQLIVFE
                     TLAALLYAFLWYGRWPGLAESAGIVLLIAGVLGGVRVFRQGGARAATDVAA"
     gene            complement(8769..9551)
                     /locus_tag="P5537_13205"
     CDS             complement(8769..9551)
                     /locus_tag="P5537_13205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004335479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HRV79042.1"
                     /translation="MSGLSLFEIALIGAAAFAAGAVNSVAGGGTFFSFPALLAIGVPP
                     VVANASNSVSLWPGSLAGAWAFRRELKRFSRSLPMLSVIAFVGGIGGGLLLLATSNAA
                     FAQLIPWLLLLATVLFAFSAQISALVKKWKPAPEGADERHIGPGGYVFQLAVSLYGGF
                     FGAGMGILMIAALAIQGFKDVHEINALKNWLSAVIYSVAVATFVIADAVSWPHTLVML
                     VTATIGGYGGAAVARKLPALWLRRFIIAVGGVLTVYYFGKTL"
     gene            9897..9972
                     /locus_tag="P5537_13210"
     tRNA            9897..9972
                     /locus_tag="P5537_13210"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9930..9932,aa:Thr,seq:cgt)
     gene            complement(10059..10298)
                     /locus_tag="P5537_13215"
     CDS             complement(10059..10298)
                     /locus_tag="P5537_13215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79043.1"
                     /translation="MNTLPRFHIRKNDGLYQPIPFLFVTERMCAEILAEREEIAGKLP
                     EAARKRQQALFARYDPRVSADAFGGLLNLFGNPAD"
     gene            10465..10998
                     /locus_tag="P5537_13220"
     CDS             10465..10998
                     /locus_tag="P5537_13220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HRV79044.1"
                     /translation="MKTSLILTLIGPDRPGLVSAVSACAGAHGANWMESRLARLAGQF
                     AGVVRLEVDAAAADGLERGLLGLGEEGLKLAVVRTDVAAAAQPHLARLELVGHDRPGI
                     VRDISAVLARHGVSIDALETACESASMSGEPLFRARAELAVPAGVVLTAVRSDLEALA
                     NELMVDLEFEEMADSAG"
     gene            11113..>11614
                     /locus_tag="P5537_13225"
     CDS             11113..>11614
                     /locus_tag="P5537_13225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HRV79045.1"
                     /translation="MQIENGVFVVSGGGSGLGAASARMLVEAGGRVVLADVNAQAGEA
                     LAAELGAAACFVQTDVTDADSAKAAIDAAVQRFGGLNGLVSCAGVAPAEKVVGREGPH
                     RLESFARTVSINLIGTFNMLRLAADVMSKAEPDAGGERGVIVNTASVAAFDGQVGQAG
                     YASSKAG"
BASE COUNT         1848 a         3862 c         4224 g         1680 t
ORIGIN      
        1 gatgaagcgc tgggagaaga ccggcctgct gaagttcgag gacaagaacg gcgacggtcg
       61 catccagtac tacaacgaca agaccaagag cgccgacgcc aaggccaagg ccgaagcggc
      121 cggctggaag ggcaacgagc tgacggtgaa cgccgacatc atggtgatgg cgaaccccga
      181 gatcgcgctg ctgcccaact gggtgatcgc gctggtcgcc gcgggtggcc tggctgccgc
      241 gctgtcgacc gctgccggcc tgctgatggc gatctcgtcc gcggtgtcgc acgacttggt
      301 caagggcgtg ttcaacccga acatcagtga caagaacgag ctgctcgcag gcaagatctc
      361 gatggcggtc gccatcgtca tcgcgggcta cctcggtctc aacccgccgg gcttcgccgc
      421 cggtacggtc gcgctggcct tcggtatcgc cgcctcctcg ctgttcccgg cgatcatgat
      481 gggcatcttc tccaagaaga tgaacaagga aggtgcgatc gcgggcatgc tggccggcct
      541 gttcgtcacg ctgttctacg tgttcgcgca caagggcatc ttcttcgtga agggcaccga
      601 gttcatcgat ctgatcggcg gcgccaacag cttcttcggc atcacgccgg aagccttcgg
      661 tgcggtcggt gcgatcgtga acttcatcgt cgcgatcgtg gtcgacaagg tgaccaagga
      721 gccgccggag cacatccagc acatggtcga ggcggtgcgt atcccgcgcg gctcgaagct
      781 ggtggacggc gcccactgat cggcaccgtc gtcacggaca gcgcggtacg gcagcatcgt
      841 gccgtaccgc gccaccggag ccccgccggt tggattggcg gggcttttcc tttgtggcac
      901 cttctgacgc gatgcggcag ccgccgcacg cagcggagca tcacatgatc ttcaacgcaa
      961 gcatcgccct caactggatt ctcttcctcg ccctgttccc gatcgccttc ttctggttcc
     1021 ggcggtcgtg gcgcatcctg ttccggcgtg atttttccga ggtcgcgctc aagcgcggca
     1081 tgccgccagc cgatccggcg cgcttcgccc cctacaccct ggcggtcaac ctgatcggcg
     1141 gtggggtgat cgtgttcgtg atcttcgggg tggtcgccgc catcctcgac ttcgagacct
     1201 ggaccgcgat cgcgggggtc acgatctggt tcaagttctt cgccgactac atcgtcagcc
     1261 gccacgcgca cccgatcgtg ccgcggcgca agaagctcga ggaagcgggg cagggcccca
     1321 agatttgaat ggcgtcgtag tgccgatgtc gatcggcacg ctgccgctca atgccgacta
     1381 ttgacccggt agcgccggtc gagccggttc atggcgacca cgtagatcac gatgatcgcg
     1441 agatagacca gcagcgcgcc ctgggcgaac aggtagaagc ccagcggaaa gccgagaaag
     1501 ctcaccgtgt tgagcgcgct ggcgaaatac cctccgacga aggtcacgcc gaaccacacg
     1561 ccgagcagcg tgaaggtcag gcggagattg ctgcgccagt aggcgcgctg gcggtcgtcg
     1621 agttccattc ttgtcgcggc ttgcgcgccc gactccccgc ggagccgggc gcttgcggcc
     1681 tcaatggttg ccgttgccgc cgctcgagaa cacccgcgcc agctcggcct ggatgtcctg
     1741 cggcgccggc tcgtggccgc cggcctcgag cacgaactcg ctctcgccgg cgcagatcgc
     1801 cttcagccgg ctctcgaagc cttccagcgc ggccatcggc acgcgcgccg agatcagcgt
     1861 ccagcccggc gcggggctgt cggtcgcggt caggcggccg cggcgaccgg cgagctccgc
     1921 gctgacctcg ccgaagagcg cgtccgccac cttgacctgc acgtcgagca gcggctcgag
     1981 caccatcggc cgcgcgccca gcaccgcctc gatcagcgca tggcggccgg cggtgacgaa
     2041 ggagacctcg ttcgagtcga ccgcgtggtg cttgccgtcg gtgatcacga cgcggatgtc
     2101 ctgcagcggg aagccggcga gcgcgccctc ggcgagcgcc tgacgcacgc ccttctcgac
     2161 cgcgggcatg aagttggtcg ggatggtgcc gcccttgacc tcgtcgccga gctcgatgcc
     2221 ggcgccgcgc ggcagcggct cgacgcgcag cgcgacctcg ccgaactggc cggcgccgcc
     2281 gctctgcttc ttgtgacggt agcgcgcctc ggccaccacg gtgatcgtct cgcggtaggg
     2341 aatgctcggc gtcgcggtgt cgagctgcag gttccagcgc gcggcgagct cgtcgagcac
     2401 gatcttgagg tgctgctcgc ccaagccgcg caccacggtg cggcggtggc gggcatcgaa
     2461 gctgacctcg aggcaggggt cttcttccat caggcgggcg agcgcctcgg agagcttctg
     2521 ctcgtcggcc ggcttgcgcg tcatcagcgc gaggccgaac accggctgcg gccaggccgc
     2581 gggggcgagg tggtagtagt cctcgtcgtg cgagtcgtgc agcaccgcat cgcgggtgag
     2641 ctcgtccacg cgcgccaccg cgcacaggtc gccgggcacc gcgagcgcgg tctcgaccgt
     2701 gttcttgccc tgcatgcgca gcaggtgggc gaccttgaag ggcttgcggc cgtcgccgat
     2761 gtagagctgc gagttgggcg tgacctggcc ctgatgcacg cggaacaggc cgagcttgcc
     2821 gcggtagggg tcgttggcga tctggaagac gtgggcgacg acgtggcgct cggcgtcgag
     2881 cacgacctcg acggccgccg ccgcagcgcc ctcgcccttg aggaaggcgg gcacgttggc
     2941 ctcggtgggg tcgggggcga gcttgccgag gatgtcgagc aactcgcgca cgccggcgcc
     3001 gctacgcgcg gagacgaagc acaccggcac caggtggcct tcgcgcaggg cctgctcgaa
     3061 gggggcgtgg agctgctcgg ggtcgagcga ctcgccctgc tcgaggtatt gcgccatcag
     3121 cgcctcgtcg agttcgacga cctggtcgac gatcgcgtcg tgcgccgccg aggggctgga
     3181 gaaggcggtg gcggcggcgt tgtcggggga gaagaagcag tcgatgacgc ggctgccgtc
     3241 ggcagacggc aggttgatcg gcaggcactc gcggccgaag gtggcggcga tggcgtccat
     3301 cagcgcgccg aggtcggcgc ccggggcgtc gatcttgttg accacgatca tgcggcactt
     3361 gcccttcgcg gcgtccatca tgcgccgggt gccgctctcg atgccggccg cggcgttgat
     3421 caccaccgcg gcggtgtcgg ccgcgggcag cgccaccagg gcgcgaccac tcaggtcagg
     3481 caggcccggg gtgtcgagca ggttgatcca gtggcctgcc cactccaggt ggaccagcgc
     3541 cgcgtgcagc gagtggccca tcgccttttc ctgcgggtcg aagtcggcga ccgtgtcgcc
     3601 gcgctccacg ctgccgggtg cgccgatctc gccggcggcg gcgagcaggg cctcgaccag
     3661 ggtggtcttg ccgctgccgg cgtggccgaa gagggccagg ttgcggatgt cgtgaaccga
     3721 gctgggggtc atcgtgtgcc tctctcttgc gattgaatgc gattgccctc aagtctgtgc
     3781 ctgtcgggcg cgcgtggcaa tgtggcaggt caaaacccgc gccgctcccg gggccgctca
     3841 ggcgctgcgc aggccggcga ggcgggtgag caggatggcc gcgagcggca ccacgagcgc
     3901 gatcaccgtc accgtgacca gcagctcgcc gagcgcgccg tagtcggccg gggtggtgat
     3961 cgcaccggtg gcggcgtccc tgacctcgcg cgcgatcgtg tgcagctggt tgaggtactt
     4021 cgtgccgagc tgagaggccg acagcgccag gttggtgaag gacgccatga ccgcgaagaa
     4081 ggtcgccttg aggtgcgctg gcgccgagtt cgcgatccac gccagcatcg gcaccatcga
     4141 cacctggccg agcggcgact cgagcgcggt gttggcgatg gcgatgaagc gcgcgtccac
     4201 cacgccgccg gtgtgcgctg cggtccattc gtgcaggccg tggaacatgc cgatgatcgg
     4261 cagcgacagc gcggtggtgg cgacggtgag gaagatcacg atctgcgcga tcgacttctc
     4321 ggccatgaag cggcggaaca ggaacaggcc ggccaatgtg agcgcgctgg tgatgaggtc
     4381 gagccgcgac aggaagctct ggtcgaagcc gagctcgtcg atcatccacc agctcgcccc
     4441 ggcgcccggg ccgggcaggg cgcggaaggc gaagatgatg atgaccgtgc cgagaagggt
     4501 acgcgcggcc tcgggcgaga gctcgcgcag caggcgagtg atcatgaacc cgatgatcgc
     4561 gaacgaggtg gcgaagatga tctcctggcc gtactcgatg cccgacagcc cgacgctgat
     4621 ggtgagcgcg acgaacaccg cgctgccgcc gaggatccac cagttgggcg cggtcttctc
     4681 ttccgggtcg tggagcaggc gatcgatctc ggcgcggctg cgcccgagcg cggccagccg
     4741 cttcgcctcg cggcgcttga ggaagccgcc gagcagcacg ccgctcaccg acagcagcgg
     4801 gatgatcagc gcgagctcgt agatgcgcag atagatggcc accttgtcgg cctcgggcag
     4861 gttctcggag ccctggaaca tcgccacgtt ggcgagcgac accatcaccg tgccgccgat
     4921 gatcgccacc cggccgagca tctgcatcgt ggtatgcatc aggcgcacgg tctcggcggg
     4981 gatgggctcg ccgcgcgcgt ccacgcgcgg cacggcctcg accgtcatcg cgtcggccac
     5041 cgcgtcctgc atcacgtagc ccaccggcga cagcagcacc gaaagcacga accaggcctc
     5101 gatcggcatc accgcgcgca tcgcatccgg gctgccgatc agcccgatca tgatcagcag
     5161 gctggcggcg atcaggctgg cgcccaggta gaccagcccg gccttgtgcc gccacatcag
     5221 gtcgaccagg tggccgatcg gcatcttcag cgcccacggg atgcccgccc agaagccgag
     5281 cgcggcgagg aaggcggccg acaggccgag gtagtccttg acgaagaagg tgccgacgat
     5341 gccggtgagg ccggacactc ccgccgcgca atacaccatc agcggcggca ggtaggagag
     5401 ccgcatctcg cggccgagct cgagcaggtt gcggtcgatc cagcggtaga gggcgtgcag
     5461 cacggggtcg gtctcttcgt cgtcgggtcg ggttctgagg gttctcgcag cggcgcgcgc
     5521 gcccgggccg ggctcagccc gcgaacaggc gctccaccca gggcatgatc cagggcaggg
     5581 acaccgcggt gatcagaccg ttcaatccca tcgccagcgc ggcgaaggcg cccgcctgct
     5641 cgctgacctg gaaggcgcgc gcagtaccga tgccgtgcga ggcgatgccg atcgcgaagc
     5701 cgtgcaccgc gtggtcgctg acgtgcaggc ggcgcatcac gcctcgcccg aacactgcgc
     5761 cgatgatgcc ggcgctgatt accagcaccg cggtgagcga gggcaggccg ccgatgcgct
     5821 cggccacgcc catcgcgatc ggcgtggtca cgctcttggg cgcgagcgac atcagcgact
     5881 cgcggctgcc gccgagcagc gcgccgatgc cccaggccga caacgccgcg gtcagcgagc
     5941 cggcaacgag cgcgatcagc agcggcccgg ccatcgactt cagccgcggc cactgcgcat
     6001 ggagcgggat cgccagcgcg acggtggccg ggccgagcag gaagtgcacg aactgcgcgc
     6061 cgtcgaaata ggcctggtag ggcgtgccgg tggcgagcag caggctggcg aggatggcca
     6121 cgctgatcag caccgggttg gcgagcggat ggaaaccgac gcgcttgtag atccagaacg
     6181 ccgcctggta ggcgagcagg gtcagtgtca ggccgagcag cggcgaggtg gatagataga
     6241 cccagatctc ctcgaggttc gggttcattg ggcggcctcc gtcgtcgcct tggcgcgctt
     6301 gtgggtgagc gccttgagca ccagcgcggt caccgcgagc gcgaggaagg tgctgaggaa
     6361 cagcgccacc agcagcggca gccattcggc ggcgatgcgg tcgccgtaga tcacgatgcc
     6421 ggtgcctgcg ggcacgaaca gcagcgacag gtgctgcagc agctggccgg aggtctggcg
     6481 caggccttcg cccgggccgc cgcggatgag cagcgcgagg aagagcaggg ccatgccgat
     6541 caccgggccg gggatcggca gcgccagtgc gcgggcgatg acctcgccgg cgagctggaa
     6601 gacgaggagc agggtgaggg cggcgatcat ggtcgggatc cttcgcgagg gctctggaag
     6661 gggggcgtac gggcgcgccg agggggcggg cgaatcgact ttacagcagc gcgtggccga
     6721 ccgcgcgcac cgcgatgccg accacggccc cgagcgcggc cggcttccac accgcagcca
     6781 cgcggcggcc ggcggagatc agcaccgcca ccccggcaac atcaaatggg tgaatcagga
     6841 agccggcgtt cgagttcagg gtggcgacgg tggtcgtgcc cgccttcagc atctcgtcca
     6901 tcacgcccat catcgcggtg ccgccggcga tgtacttggt cagcgtcagc aggatcagcg
     6961 cggggtcgag ctcgaagacg cgcagcagcg gggcgagcag cgcggtgagc gcatcgatgc
     7021 cgccgctcgc gcgcagcgcc atcaccgcca ccagcgcgag caccagcatc gggatcgcgc
     7081 ccacggagat cttgaaggcc tcggcgccgg cgcggttgat gacgtcgagc acgcccttgg
     7141 cgtcgtcggc gacgcggtgg tgcagggtct cgtcgagcgg cgcctcggct gccgacaggc
     7201 cgcggccgaa gccgtggtag gtcaccgccg ctgcggccag gccgccgatc accgacagca
     7261 ccagcgccgg cccgaaggcg agccccatcg cggccatcgg gaaggtcacg ttggcctgcg
     7321 ccatcgccat caccatcgcc agcgtggcgg cgaggtggcg gtcggaggcg ccgcggcctt
     7381 ccatcatggt gagcgtggcc accggcgcgg cgaagctcac caggttgatc tgcagcgcgg
     7441 cgaacacccc cagcccggtg aggccgagcg gacgcagcag cggcgccagg cgggccacca
     7501 cccagtcgag cacgccgcgc gcctcgagca ggcgcatcag cgacagcatc accaccatga
     7561 tcggcagcag cacgaagagg gaaagctcga cgccggagcg gccggcctcg aggatgatgc
     7621 gggtgagttg gtccatcggc gcgagagctg ggatttgctg cagtgcaaaa acgaaatgat
     7681 atcgtgtccg gcgggatgcc ggcgcggctg gcgcagactc tgcggcgatg caccgttccg
     7741 ccccccgagc cttcccggac ctgtgctttc ccgtccctac gctgccacgt ccgtcgcggc
     7801 gcgcgcgcca ccctggcgga acaccctcac gccgccgagc acgccggcga tcaacagcac
     7861 gatgcctgcg ctctcggcca ggcccggcca gcgtccgtac cacaggaagg cgtagagcag
     7921 cgcggcgagc gtctcgaaca cgatcagctg gcccaccagc gccgccggca gcaggtggct
     7981 ggcgcggttc cacagcaggg tgccgagcca ggacgcggcc agcccgagca ggatgcacat
     8041 gccgacgaag gcctcggggc gggggccgag cggccacgcg aagcccgggc cgccgggcgc
     8101 gagccgggtg tcccacagcc agtagccgac gccggcgacg atcgccaccg gcagcgtcgc
     8161 cagcccctgc gcggtcgccc acgcgcgcgc cagcccggcg ccgcgggcgc gcagccagcg
     8221 gctgttgcgg atcggatacc aggtccagca accgagtgcg aacagcccga agccgatgcc
     8281 gaggaggtag tcggcggagg cgtccgcggg cagcgcctgc gcgctcgccg aatgcaccgc
     8341 gaacaggccg ccgaggatca gcgccagcgg tgccgccagg cgcgcccagg gcgcgctgtc
     8401 ctcgccgccg ccgcgacggc ggtcgagcag gttcgcggtg atcgcgatca ccaccggcag
     8461 cgtgccgatg atcagggtcg gcaccggccc cccggcgagc tggatcgcgc tcgccagcgt
     8521 ggagtaatag agcaggttgc cgatcagcgc gagcttgacc gcctcgatcc agtcggcgcg
     8581 cgtgaggcgg gcgagcgcgg cgcgatcgaa ccaggccagg ccgagcgcga gcacgccgaa
     8641 ggcgaggtag cgcccgatcg cgagcatgaa gggcgggtag tcggcgagca gcagcggggt
     8701 gaggaacacc aggccccaca gcaggcccgc gcctagggcg gcggagagtc cggcgagcat
     8761 cggcgcgctc agagcgtctt gccgaagtag tacacggtga gcacgccacc gaccgcgatg
     8821 atgaagcggc gcagccacag cgccggcagc ttgcgcgcca ccgccgcacc tccgtagccg
     8881 ccgatggtcg cggtgaccag catgaccagg gtgtgcggcc acgacaccgc gtccgcgatc
     8941 acgaaggtcg ccaccgcgac gctatagatc accgccgaca gccagttctt cagtgcgttg
     9001 atctcgtgca cgtccttgaa gccctggatg gcgagcgcgg cgatcatcag gatgcccatg
     9061 ccggcgccga agaagccgcc atacagggag accgcgagct ggaacacgta gccgcccggg
     9121 ccgatatggc gctcgtcggc gccttccggg gcgggtttcc acttcttcac cagcgcggag
     9181 atctgcgcgc tgaaggcgaa cagcacggtg gcaagcagca gcagccaggg gatcagctgc
     9241 gcgaacgcgg cgttggaggt cgccagcagc agcaggccgc cgccgatgcc gccgacgaag
     9301 gcgatcaccg agagcatcgg caggctgcgg gagaagcgct tgagctcgcg ccggaacgcc
     9361 caggcgccgg cgaggctgcc cggccacagc gacaccgagt tgctcgcgtt ggccaccacc
     9421 ggcggcacgc cgatcgcgag cagggcaggg aaggagaaga aggtgccgcc gccggcgacc
     9481 gaattcaccg cacctgcggc aaaggcggcg gcgccgatga gggcgatctc gaagaggctg
     9541 aggccggaca tggggagagc gggacgtggg gaggctgggt cggcaggcgt ggtccgtgcc
     9601 ggagcgcggc gggcccggag atggcgcaac tgccgcggga gcgagccccc gcggcgctgc
     9661 gttcttgctc gggctggtct cctccgccct gaattggcgc gcattctaat ggagccgcat
     9721 agcaaaaagt aggtgtggga gaagaatttt ctatcgaata cgggttctcc ccgatgcttc
     9781 gcgcgctcgt gtcgaccgcc gggaggcgca gtcgaagggc cggcagcacc gcatgcctag
     9841 ccctgcgcgc gcggtgttgc cgcgcccctc gcgctgggtt aagatgcgcg cccttggccg
     9901 gtgtagctca gttggtagag cagcgcattc gtaatgcgaa ggtcgggagt tcgagtctct
     9961 tctccggcac caatggtttc aggcacttag ggcgattctg cggaatcgcc cttttgcttt
    10021 ccgactttcg tgtagccctc ttgtcagtgt tgcgcacgct aatcggccgg attgccgaac
    10081 aggttcagca ggccaccgaa ggcgtccgcg ctcacgcgcg ggtcgtagcg cgcgaacagc
    10141 gcctgctggc gcttgcgcgc ggcctcgggc agctttccgg cgatctcctc gcgctcggcg
    10201 aggatctccg cgcacatccg ttcggtcacg aacaggaagg gaatcggctg gtagaggccg
    10261 tcgttcttcc ggatgtggaa acgcggcagc gtgttcattc tgtctcctcc catgctcgta
    10321 acggccgcga actcccgttc ccgtggccgc tgggttatcg tgtcggctcc catttcaatt
    10381 atctcaggcc tcgcggggat cgcccttgat gccgcgcaga gggacgcggg gcgctcgcgc
    10441 tgcggggccg gacggagacc aagcatgaag acttccctga tccttaccct gatcggcccg
    10501 gatcgtcccg gcctggtgag tgcggtgtcg gcctgcgccg gggcccacgg cgcgaactgg
    10561 atggagagcc gcctcgcccg tctggccggc cagttcgccg gtgtcgtgcg cctggaggtg
    10621 gatgccgctg cggccgatgg gctcgagcgc ggcctgctgg ggctgggcga ggagggactc
    10681 aagctcgcgg tggtgcggac cgatgtggcg gcggccgcgc agccgcacct ggcgcggctc
    10741 gagctggtgg ggcacgaccg tcccggcatc gtgcgcgaca tctctgcagt gctcgcccgc
    10801 cacggtgtca gcatcgacgc gctcgagacg gcctgcgaga gtgcctcgat gagcggcgag
    10861 cccttgttcc gcgcgcgcgc ggaactggcg gtgccggccg gggtcgtgct caccgcggtg
    10921 cgcagcgacc tcgaggcgct cgccaacgag ttgatggtcg atctcgaatt cgaggagatg
    10981 gcggattcgg ctggttgagg accgggacgg cctggggtcg ggcgattcga ttgacgccta
    11041 cgtcaacgta atttaaggtg ctgcaccgca gcgacggcct tcgccgtcca cgattttcct
    11101 gggagaaaag cgatgcaaat cgagaatggc gtattcgtgg tgagcggcgg aggctcgggc
    11161 ctgggtgcgg cgagcgcacg catgctggtc gaggctggcg gccgcgtggt gctggccgac
    11221 gtcaacgcac aggcgggcga ggcgctcgct gcggaactcg gcgcggcagc ctgcttcgtt
    11281 cagaccgacg tcaccgatgc cgacagcgcc aaggcggcga ttgatgctgc ggtgcagcgc
    11341 ttcggcgggc tcaacggcct ggtcagctgt gctggcgtgg cgccggcaga gaaggtggtg
    11401 ggccgcgaag gcccgcatcg gctcgagagc ttcgcgcgca ccgtgtcgat caacctcatc
    11461 ggcaccttca acatgctgcg cctggccgcc gacgtgatga gcaaggccga acccgacgcc
    11521 ggtggcgagc gcggggtgat cgtcaatacc gcctcggtgg ccgccttcga cggccaggtc
    11581 ggccaggccg gctacgcctc gtcgaaggcc ggcg
//
LOCUS       DAOTIN010000104        11595 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_6616_length_11595_cov_7.796707, whole genome shotgun sequence.
ACCESSION   DAOTIN010000104 DAOTIN010000000
VERSION     DAOTIN010000104.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 11595)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 11595)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11595
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6616_length_11595_cov_7.796707"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(339..776)
                     /locus_tag="P5537_13230"
     CDS             complement(339..776)
                     /locus_tag="P5537_13230"
                     /inference="COORDINATES: protein motif:HMM:NF024834.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="c-type cytochrome"
                     /protein_id="HRV79046.1"
                     /translation="MRRSGMIALTLAMSLGAHVSQAADAGQQQDYGKHICDSKCAACH
                     GVDGKGNGPFAANLVKKPSDLTTIAKNNKGVVPVMALEALIDGREEAFFHGTREMPVW
                     GHELRAEAGADWPAYMGVSFNPEVFVRGRIMALIDYIGRIQEK"
     gene            1171..4770
                     /gene="recC"
                     /locus_tag="P5537_13235"
     CDS             1171..4770
                     /gene="recC"
                     /locus_tag="P5537_13235"
                     /EC_number="3.1.11.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009338 - exodeoxyribonuclease V complex
                     [Evidence IEA];
                     GO_function: GO:0008854 - exodeoxyribonuclease V activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit gamma"
                     /protein_id="HRV79047.1"
                     /translation="MTTDRSAPPLPPGFIALHGNRIETLRDTVAGWLAQHPLAPLESE
                     VILVQSNGMAEWVKMAIARRAGVCAAAAVQLPARFQWQTYRQVLGRAQVPARSPLDKT
                     ALAWRLMRLLPEVLAEPGFAPVAGYLAEDDPGRRFQLALRIADLYDQYQVHRPDWLDT
                     WGDGREFLLDAGRVATPLPEDQRWQARLWQRVLDELEPQQRALTRPQLHDRVLAALAA
                     MAEDTALRPAAALPRRVVLFGMTHVPLPTLQLLAALSRHAQVLLAIPNPCRFHWADIL
                     DGREWLRIARRRHPLREGRELQDVGLDAMHLHAHPLLAAWGRQARDFVRQLDAFDDTE
                     QTRARFPLARIDLFDDEDDAHDGAAPALLVQVQRHIRDLTPLAEHPRPPVPAEDRSIV
                     FHLAHSPVRELEILHDQLLALLAREDAGKPLRPRDIVVMVPSIDDFAPAIRAVFGQYG
                     RHDARHIPFDIADLSARASSPLMSAVEWLLRIRHDRCRLSDLGALLDVPAIAARFGLA
                     EDGLPRLTRWMSGAGIRWGLDAAHRAGLGLDACGEQNSALFGLRRMLMGYAAGRSEAD
                     VEAPFAGIEPYDEVGGLDAELAGALARLVERLIRWQADSRRPATPAAWAGRLRALLAD
                     LVRAVDDADRQTLAALDDALERWIEACDEARFEAELPLDVAAEAWLSALETPALDKRF
                     RAGGVTFCTLMPMRAIPFEVVCLLGMNDGDYPRRSPRSDFDLMALPGQQRPGDRARRD
                     DDRQLMLEALLSARRVLYLSWCGFNVRDNSAQPPSVLVAQLRDYLAAGWSPEVVAERT
                     RAHPLQPFSRRYFEPGTPLFTYAREWRAAHVDTTYVDTAAGAAQGEQAAAEAAGGAVR
                     PARGEPAAPALPPFLPDPAVPLTISALAAFLRNPVKVFFRERLGVVYEDADEALPDEE
                     AFGFDGLEEHGLVDELAGAVLAELASLKPGELPAFALETAVEAHLLRIQRAGRLPIGG
                     LGLRARAALGEAVLPLLRAWRLARASHPLDAERRSLRFEHAGALMEDWLDHRVRADAH
                     ELPLWLAHDPGRLLEDADKGTLRPWRLLQPWVRSLLAAAADCPSGGLLVGRDASVHIV
                     PTDPAVARALLARLIEAWIAGLGEPLPVAARSALALVGGGKPAEAYEGSEHRRGEVEE
                     ASLARCYPDYATLTEDGRFGHLARELYAPLLDWIESHAEAIPHPASAPLEPAR"
     gene            4767..8654
                     /gene="recB"
                     /locus_tag="P5537_13240"
     CDS             4767..8654
                     /gene="recB"
                     /locus_tag="P5537_13240"
                     /EC_number="3.1.11.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009338 - exodeoxyribonuclease V complex
                     [Evidence IEA];
                     GO_function: GO:0008854 - exodeoxyribonuclease V activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit beta"
                     /protein_id="HRV79048.1"
                     /translation="MSHRLDPVRFPLRGSRLIEASAGTGKTWTIAALYLRLVLGHGDA
                     DTAFVRPLLPAEILVMTFTRAATRELSERIRERLREAAAWFRDEESGREPDPLLDALL
                     AAYPDPAARRNAAWRLAMAAEAMDDAAVFTIDAWCQRMLREHAFDSGTPFDEELAADE
                     SVLLTEAAQDYWRQHCYPLAGEALELALSQWADVHALVADVRELVGQPLQGAQRDDGA
                     GQAGEEDPVGRPEARRDPAGGESLATLIERVGSAHRRALIALAQGWAERARAMKDWLD
                     EELAANARQWNRTRLHERYYTPWLETLEQWARNPLERKLELSDSARHRLTPDGLREAR
                     KADAPAPALPEHFAAFARLIQALGALRDPRSALRVHAATRVGERLAALKHQARSFGFA
                     DLLERLDRALAGPQGARLRERILAQYPVALIDEFQDTSPLQYRLFDALYRAADDDPRS
                     ALLLIGDPKQSIYGFRGADIYSYLQARRATAGRHYMLGTNFRSAKALVSAVNTWFAQA
                     EQRPGAGAFGFRDAADNALPFEPVAAKGRDEVFRADGGVAPALLIHHDLALRGTGEVR
                     RLFAARCAERIVAWLNDEHAGFQAPGKDFQRLRPADIAVLVRSGREAAEVRRALRRRG
                     VASVYLSDKDSVFASDEARDLLHWLRAAASPLDARLVRAALATRTVGLSIAELAWLAS
                     SDAAFDARSEQFRALHAAWRELGVLTMLRRSLHLLELPARWLAEPEGERRLTNFLHLA
                     ELLQQASATLEGEAALVRWLAMAIEAGGSGGGEEQVVRLESDADLVKVVTVHKSKGLE
                     YPLVCLPFATSFRAVERRTARYLKLADADGRRQLKLDYGDADLERAEAERLREDLRLF
                     YVALTRARHALWMGFAAVKIGNGKACQTHRSAPGQLLSGGAALDEAAWLAPLQALAAA
                     AAEETDTAGDADSDGRTRIALEAAAPEEAHTLLCRREALPPLQDSPPYRADFERRWSL
                     GSFSALVRDLDPTPILVPPGGVNEDGPEALEADPIRPAHVRRPAADEALAGPADADAA
                     AAPAGTLAMSGAMLARRDGAPPPWHRFPRGAFAGDFLHDLLEWLAAEGFALADNPGLE
                     AALRRRCERAGHGERAHELVEWMRALLAARLPSLGAALQDLRVLITEMEFWLPSAHLQ
                     AQAVDALCQRGLLHGQPRPALPQRELHGMLMGFADLVFEHEGRYWVLDYKSNSLGEDG
                     AAYDHAALEAAMAHHRYDVQAAIYLLALHRLLRARLGGAYEPARQLGGALYFFLRGID
                     GPARGEYAIPATPALLALLDTLDHLLADEASLA"
     gene            8651..10789
                     /gene="recD"
                     /locus_tag="P5537_13245"
     CDS             8651..10789
                     /gene="recD"
                     /locus_tag="P5537_13245"
                     /EC_number="3.1.11.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004319516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009338 - exodeoxyribonuclease V complex
                     [Evidence IEA];
                     GO_function: GO:0008854 - exodeoxyribonuclease V activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit alpha"
                     /protein_id="HRV79049.1"
                     /translation="MSPIHASPATAGASPLASSTTAPSHASMAPGMGLTSSRAGQSPR
                     TPTAAATATLLATLDAWTDAGLLRQLDSAFARFVASLDPDAPPALLVAAAVLARMEGR
                     GHSCLPLAPLATAEQDLLAWPVEAQPAIAALWASLPANPAAWLAVLQQSPVVRRVGRD
                     PELGQPLLIDGPDDAPRLYLRRYWQYERSVAAAVVERCARPEAVDETRARTWLDRLFP
                     TPADAAARKDAIDWQKLACAIALRGRLSILTGGPGTGKTYTAARLLALLLATHPAPER
                     LRIALAAPTGKAAARLRQAIDGSLQALQHSLGAHLDLAALTRRIGAARTLHALLGARP
                     DTRRFRHHAGNPLDVDVVIVDEASMVHLEMMAALLEALPPGARLVLLGDKDQLASVEA
                     GAVLGDLCRDAEAGRYDAETARYLLATTGEALPARYLAAAGTAPALAQHTVMLRVSRR
                     FEGPIGALALAVNAARDPALPARLLREDASGALHGVEGGPVAAVIALALDGREGASAC
                     YRDYLERLARGPAGKDGAAHAAWAADILKAFDRFRVLCAVREGDWGVAGLNRAIEHAL
                     ARARLLSPRGSWYPGRPVMVTRNDPALGVFNGDIGITLPAAEGGGLRVHFLDGEALRS
                     VAVSRLAHVETAFAMTVHKSQGSEFEHTALVLAAQSGNVLTRELIYTAITRARKAFSL
                     VAEREGLLENGVLQATRRESGLLGFQGTTG"
     gene            10786..11007
                     /locus_tag="P5537_13250"
     CDS             10786..11007
                     /locus_tag="P5537_13250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004379010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79050.1"
                     /translation="MKKTGSAARSLALCLLAALCLGGCAVTAVAGAVVTVAATAVSVT
                     ATVVETTVDVAAAGVEAVVGEDEEEQAEE"
     assembly_gap    11367..11466
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
BASE COUNT         1512 a         4505 c         3972 g         1506 t
ORIGIN      
        1 acgcgcgacg gttcatgtag gagcgccggc aggcgcgaat gcggcgcccg agagcacgtc
       61 gccagcctgc tgcgctggct gctcggctgc gggggggcgg acggttgaat gtgggcgccg
      121 ctttttcccc agcggctttc cttgaagaac cgcgagctca tcaatattgc gctgccaggc
      181 tcggtcgccc cggactccgg tcgagccctc ggccgccacg acgccacccg ccgactcccg
      241 cacgggagat cgatgctgaa aaacgccagc ggccccccga ggggcgccgc tggcgtgttc
      301 aggacgcagc ggctaggcag ccgctgcaag gacgtccgtc acttctcctg gatgcgtccg
      361 atgtagtcga tcagcgccat gatgcggccg cggacaaaga cctccgggtt gaaggacacg
      421 cccatgtagg cgggccagtc tgctccggcc tcggcgcgga gttcgtgacc ccacaccggc
      481 atctcgcgcg ttccgtggaa gaaggcctct tcccgaccat cgatcagcgc ctcgagcgcc
      541 atcaccggca caacgccctt gttgttcttc gcgatcgtcg tcaggtcgga cggcttcttg
      601 accagattgg cagcgaaggg gccgttgccc ttgccgtcga caccatgaca ggcggcacac
      661 ttcgagtcgc agatgtgttt tccataatcc tgctgctgcc ccgcatcggc ggcctgggaa
      721 acgtgcgcac ccaaggacat cgccagcgtc agcgcaatca tcccagatcg tctcatgaca
      781 aactcctttc gaagcgggcg cagaatgcac cctgggttga ggaaaacatt tcttaaaaac
      841 gtattttcag ctattaatcc ggcgttattg cttcgaaatg cattgaattc gtactcagcc
      901 aggagctgga gcgcttatcc atcaaagatg acttttctgt tactacttgt cttgaaacta
      961 atccttgtac aaggtttttc ctgggctttt taaccctttt cgcatgccct aactgcatat
     1021 ctatggcgca ataaaagccc gctattcatc ccctgatcgg cgatgcccgt gcgcgctcca
     1081 gccgaggcaa gcgacaatgc gacgccgcgc gtcgcaaaac gccggaacat gtcggcaatg
     1141 ccccacgccc ccgcaacgaa caccccagcc atgaccaccg accgctccgc cccgcccctc
     1201 ccccccggct tcatcgccct gcacggcaac cgcatcgaga ccctgcgcga caccgtcgcc
     1261 ggctggctgg cgcagcatcc gctcgcgccg ctcgagtccg aggtgatcct ggtgcagagc
     1321 aacggcatgg ccgagtgggt gaagatggcg atcgcccgcc gggctggggt gtgcgcggcg
     1381 gcggcggtgc agctgccggc gcgcttccag tggcagacct accgccaggt gctcgggcgc
     1441 gcgcaggtgc cggcgcgctc gccgctggac aagaccgcgc tcgcctggcg cctgatgcgg
     1501 ctgctgcccg aggtgctcgc cgagccgggc ttcgcgccgg tggcgggcta cctcgcggag
     1561 gacgaccccg gccgccgctt ccagctcgcg ctgcgcatcg ccgacctcta cgaccagtac
     1621 caggtgcacc ggcccgactg gctcgacacc tggggcgacg ggcgcgaatt cctgctcgac
     1681 gccggccgcg tcgctacgcc gctgcccgag gaccagcgct ggcaggcgcg actgtggcag
     1741 cgcgtgctcg acgagctcga gccgcagcag cgcgcactca cccggccgca gctgcacgac
     1801 cgcgtgctcg ccgcgctggc ggcgatggcc gaggacaccg ccctgcgtcc ggccgccgcc
     1861 ctgccgcgcc gcgtcgtgct cttcggcatg acccacgtgc cgctgcccac gctgcagctg
     1921 ctcgccgcgc tgtcgcgcca cgcgcaggtg ctgctcgcca tccccaaccc ctgccgcttc
     1981 cactgggccg acatcctgga cgggcgcgag tggctgcgca tcgcgcgccg ccgccatccg
     2041 ctgcgcgagg ggcgcgagct gcaggacgtc gggctggacg cgatgcacct ccacgcccac
     2101 ccgctgctcg ccgcctgggg ccgccaggcg cgcgacttcg tgcgccagct cgacgccttc
     2161 gacgacaccg agcagacgcg cgcgcgcttt ccgctcgccc gcatcgacct cttcgacgac
     2221 gaagacgacg cgcacgacgg cgccgcgccc gcgctgctcg tccaggtcca gcgccacatc
     2281 cgcgacctca ccccgctcgc cgagcatccg cgcccgcccg tgccggccga ggaccgctcg
     2341 atcgtcttcc acctcgccca cagcccggtg cgcgagctcg agatcctcca cgaccagctc
     2401 ctcgccctgc tcgcccgcga ggacgcaggc aaacccctgc gcccgcgcga catcgtggtg
     2461 atggtgccct cgatcgacga cttcgcgccg gcgatccgcg cggtcttcgg ccagtacggc
     2521 cgccacgacg cgcgccacat ccccttcgac atcgccgacc tgtcggcgcg cgcgagcagc
     2581 ccgctgatga gcgcggtgga gtggctgctg cgcatccggc acgaccgctg ccggctgtcc
     2641 gacctcggcg cgctgctcga cgtgcccgcc atcgccgccc gcttcggcct cgccgaagac
     2701 ggcctgccgc ggctcacccg gtggatgagc ggcgccggca tccgctgggg gctggacgcc
     2761 gcgcatcgcg ccgggctggg gctggacgcc tgcggcgagc agaacagcgc gctcttcggc
     2821 ctgcgccgca tgttgatggg ttacgccgcc gggcgatcgg aggccgacgt cgaggcgccc
     2881 ttcgccggca tcgagcccta cgacgaggtc ggcggcctcg acgccgagct cgccggcgcc
     2941 ctcgcccgcc tggtcgagcg cctgatccgc tggcaggccg acagccggcg gcccgccacc
     3001 cccgcggcct gggccgggcg cctgcgcgcc ctgctcgccg acctggtgcg cgcggtggac
     3061 gacgccgacc gccagaccct ggccgcgctc gacgacgccc tcgagcgctg gatcgaggcc
     3121 tgcgacgagg cccgcttcga ggccgagctg ccgctcgacg tcgccgccga ggcctggctg
     3181 agcgcgctcg agacgcccgc gctcgacaag cgcttccgcg ccggcggggt caccttctgc
     3241 acgctcatgc cgatgcgcgc gatccccttc gaggtggtct gcctgctcgg catgaacgac
     3301 ggcgactatc cgcgccgcag cccgcgcagc gacttcgacc tcatggccct gcccgggcag
     3361 cagcgccccg gcgaccgcgc ccgccgcgac gacgaccgcc agctcatgct cgaggccctg
     3421 ctctcggcgc gccgcgtgct ctacctgagc tggtgcggct tcaacgtgcg cgacaacagc
     3481 gcgcagccgc cctcggtgct ggtcgcccag ctgcgcgact acctcgccgc cggctggtcg
     3541 ccggaggtgg tggccgaacg cacccgcgcg cacccgctgc aacccttcag ccggcgctac
     3601 ttcgagccgg gcacgccgct gttcacctac gcgcgcgaat ggcgcgccgc gcacgtcgac
     3661 accacgtacg tcgacactgc agcgggcgcg gcgcagggcg agcaggcggc cgcagaagcc
     3721 gcgggcggcg cagtccgtcc cgcccgcggc gagcctgccg ctccggcgct gccgcccttc
     3781 ctccccgatc ccgcggtgcc gctcaccatc agcgcgctcg cggccttcct gcgcaacccg
     3841 gtcaaggtct tcttccgcga gcgcctcggc gtggtgtacg aggacgccga cgaggccctg
     3901 cccgacgagg aggccttcgg cttcgacggc ctcgaggagc acggcctggt cgacgagctc
     3961 gccggcgcgg tgctcgccga gctcgccagc ctgaagccag gcgagctgcc cgccttcgcg
     4021 ctcgaaaccg cggtcgaggc acacttgctg cgcatccagc gcgccggccg gctgccgatc
     4081 ggcggcctcg gcctgcgcgc ccgcgccgcg ctcggcgagg ccgtgctgcc gctgctgcgc
     4141 gcgtggcggc tggcacgcgc aagccatccg ctcgacgccg agcgccgcag cctgcgcttc
     4201 gagcacgccg gggcgctcat ggaagactgg ctcgaccacc gcgtgcgcgc cgacgcgcac
     4261 gagctgccct tgtggctcgc ccacgacccc ggccgcctgc tcgaggacgc cgacaagggc
     4321 acgctgcgcc cctggcgcct gctgcagccc tgggtgcgca gcctgctcgc cgccgccgcc
     4381 gactgcccga gcggcggcct gctggtcggc cgcgacgcca gcgtccacat cgtccccacc
     4441 gaccccgccg tcgcgcgcgc cctgctcgcc cgcctgatcg aggcctggat cgccggcctc
     4501 ggcgagccgc tgccggtggc ggcgcgcagc gcgctcgcgc tggtcggcgg cggcaagccg
     4561 gccgaggcct acgagggcag cgaacaccgc cgcggcgagg tcgaggaagc cagcctcgcg
     4621 cgctgctacc ccgactatgc caccctcacc gaggacggcc gcttcgggca cctcgcgcgc
     4681 gaactctacg ccccgctgct cgactggatc gagagccacg ccgaggccat cccccacccc
     4741 gcatccgcgc ccctggagcc cgcccgatga gccaccgact cgaccccgta cgcttcccgc
     4801 tgcgcggcag ccgcctcatc gaggccagcg ccggcacggg caagacgtgg accatcgccg
     4861 cgctctacct gcgcctggtg ctcggccacg gcgacgccga caccgccttc gtgcgcccgc
     4921 tgctgcccgc cgagatcctg gtgatgacct tcacccgcgc cgccacgcgc gagctctccg
     4981 agcgcatccg cgaacgcctg cgcgaggccg cggcctggtt ccgcgacgag gagtcagggc
     5041 gtgaacccga ccccctgctc gacgcgctgc tcgccgccta ccccgacccg gccgcgcgcc
     5101 gcaacgccgc ctggcgcctg gcgatggcgg ccgaggccat ggacgacgcg gcggtgttca
     5161 ccatcgacgc atggtgccag cgcatgctgc gcgagcacgc cttcgacagc ggcaccccct
     5221 tcgacgagga actcgccgcc gacgagagcg tgctgctgac cgaagccgcg caggactact
     5281 ggcgccagca ctgctacccg ctcgccggcg aggcgctgga gctcgcgctc tcgcaatggg
     5341 ccgacgtgca tgccctggtc gcggacgtgc gcgagctggt cggccagccg ctgcagggcg
     5401 cgcagcggga cgacggcgcg gggcaggcgg gcgaggagga tccggtcggg cggcccgaag
     5461 cgcggcgcga tccggccggt ggcgaatcgc tggccacgct gatcgagcgc gtcggcagcg
     5521 cccaccgccg tgcgctgatc gcgctcgcgc aaggctgggc cgagcgcgcg cgcgcgatga
     5581 aggactggct cgacgaggag ctcgccgcca acgccagaca gtggaatcgc acccggctgc
     5641 acgagcgcta ctacacgccc tggctggaga cgctcgagca gtgggcgcgc aacccgctcg
     5701 agcgcaagct cgagctcagc gacagcgccc gccaccgcct cacccccgac ggcctgcgcg
     5761 aagcgcgcaa ggccgacgcc ccggcgcccg cgctgcccga gcacttcgcc gccttcgccc
     5821 gcctgatcca ggccctcgga gccctgcgcg acccgcgcag cgcgctgcgg gtgcacgccg
     5881 ccacccgggt cggcgagcgc ctcgccgcgc tcaagcacca ggcgcgcagc ttcggcttcg
     5941 ccgacctgct cgagcgcctc gaccgcgccc tcgccggccc gcagggcgcg cgcctgcgcg
     6001 agcgcatcct cgcccagtac ccggtggcgc tgatcgacga gttccaggac acctcgccgc
     6061 tgcagtaccg cctgttcgac gcgctctacc gcgccgcgga cgacgacccg cgcagcgcgc
     6121 tgctgctgat cggcgacccc aagcagtcga tctacggctt tcgcggcgcg gacatctaca
     6181 gctacctgca ggcccgccgc gccaccgccg gccggcacta catgctgggc accaacttcc
     6241 gctcggcgaa ggcgctggta agcgcggtca acacctggtt cgcgcaggcc gagcagcgcc
     6301 ccggtgcggg cgccttcggc tttcgcgacg cggcggacaa cgccctgccc ttcgagccgg
     6361 tggcggcgaa ggggcgcgac gaggtcttcc gggccgacgg cggcgtggcg ccggcgctgc
     6421 tcatccacca cgacctggcg ctgcgcggca cgggcgaggt ccgccgcctg ttcgccgcgc
     6481 gctgcgccga gcgcatcgtc gcctggctca acgacgagca cgccggcttc caggcgcccg
     6541 gcaaggactt ccagcgcctg cgcccggccg acatcgccgt gctggtgcgc agcgggcgcg
     6601 aggccgccga ggtgcggcgc gcgctgcgcc ggcgcggcgt ggcctcggtg tatctgtcgg
     6661 acaaggactc ggtcttcgcc agcgacgagg cgcgcgacct gctgcactgg ctgcgcgcgg
     6721 cggcctcgcc gctcgacgcc cgcctggtgc gcgccgcgct cgccacccgc acggtggggc
     6781 tgtcgatcgc cgagctggcc tggctggcga gctcggacgc ggccttcgac gcgcgcagcg
     6841 aacagttccg cgcgctgcac gccgcgtggc gcgagctcgg cgtgctcacc atgctgcgcc
     6901 gcagcctgca cctgctcgag ctgcccgcgc gctggctggc cgagcccgag ggcgagcgcc
     6961 ggctcaccaa cttcctgcac ctggccgagc tgctgcagca ggccagcgcc acgctcgagg
     7021 gcgaggccgc gctggtgcgc tggctggcga tggcgatcga ggccggcggc agcggcggcg
     7081 gcgaggagca ggtggtgcgc ctggagagcg acgccgacct cgtcaaggtg gtcacggtgc
     7141 acaagagcaa gggactggaa tacccgctgg tctgcctgcc gttcgccacc agcttccgcg
     7201 cggtggagcg ccggaccgcg cgctacctca agctcgccga cgccgacggc cggcgccagc
     7261 tcaagctcga ctacggcgac gccgaccttg aacgcgccga ggccgagcgc ctgcgcgagg
     7321 acctgcgcct gttctacgtc gcgctcacgc gcgcccgcca cgcgctgtgg atgggcttcg
     7381 ccgcggtaaa gatcggcaac ggcaaggcct gccagaccca tcgcagcgcg ccgggtcagc
     7441 tactctccgg cggcgccgcg ctcgacgagg cggcctggct cgcgccgcta caggcgctgg
     7501 ccgcggccgc cgccgaggag acggacactg ccggggacgc ggacagcgac ggccgcacgc
     7561 gcatcgccct cgaagccgca gcgccggagg aagcgcacac cctgctgtgc cggcgcgagg
     7621 ccctgccacc gctgcaggac agtccgccct accgcgccga cttcgagcgc cgctggtcgc
     7681 tcggcagctt ctccgcactg gtgcgcgacc ttgaccccac gccgatcctc gtgccgccgg
     7741 gcggcgtcaa cgaggacggc cccgaagcgc tcgaggccga tcccatccgg cccgcccacg
     7801 tccgccgccc ggccgccgac gaggcgctcg ccggacctgc cgatgcggac gccgcagcag
     7861 cccccgcagg cacgctggcg atgtccggcg ccatgctcgc ccgccgcgac ggcgccccgc
     7921 cgccctggca ccgcttcccg cgcggcgcct tcgccggcga cttcctccac gacctgctcg
     7981 agtggctggc ggcggagggc ttcgcgctcg ccgacaaccc gggcctggaa gccgcgctgc
     8041 gccggcgctg cgagcgtgcc ggccatggcg agcgcgccca cgagctggtg gagtggatgc
     8101 gcgccctgct cgccgcccgc ctgcccagcc tgggcgcggc gctgcaggac ctgcgcgtgc
     8161 tgatcaccga gatggagttc tggctgccgt ccgcgcacct gcaggcgcag gcggtggacg
     8221 cgctgtgcca gcgcgggctg ctgcacggcc agccccgccc cgcgctgccg cagcgcgagc
     8281 tgcacggcat gctgatgggc ttcgccgacc tggtcttcga gcacgagggg cgctactggg
     8341 tgctggacta caagtcgaac agcctgggcg aggacggtgc cgcctacgac catgccgcgc
     8401 tcgaggcggc gatggcgcat caccgctacg acgtgcaggc ggcgatctac ctgctcgcgc
     8461 tgcatcgcct gctgcgcgca cgcctgggcg gggcctacga gcccgcgcgc cagctcggcg
     8521 gcgcgctgta tttcttcctg cgcggcatcg acgggccggc gcgcggcgag tacgccatcc
     8581 ccgcaacgcc ggcgctgctc gcgctgctcg acaccctgga ccacctgctc gccgacgagg
     8641 cctccctggc atgagcccca tccacgcctc ccccgcgact gccggcgcat ccccgctcgc
     8701 gtcgtccacc accgcaccgt cgcatgcgtc gatggcaccc ggcatggggc tgaccagcag
     8761 ccgtgccggg caatcgcccc ggacaccgac cgctgcagcg accgcaaccc tgctcgccac
     8821 cctcgacgcg tggaccgacg ccggcctgct gcgccagctc gacagcgcct tcgcccgctt
     8881 cgtcgccagc ctcgacccgg acgcgccgcc ggcgctgctg gtggccgccg ccgtgctcgc
     8941 gcgcatggag ggccgcggcc acagctgcct gccgctcgcc ccgctcgcca cggccgaaca
     9001 ggacctgctg gcctggccgg tggaggccca gccggcgatc gccgcactat gggccagcct
     9061 tcccgccaat cctgcagcct ggctcgccgt gctgcagcag agcccggtgg tgcgccgcgt
     9121 cggccgcgac cccgagctcg gccagccgct gctgatcgac gggcccgacg acgcgccccg
     9181 gctctatctg cgccgctact ggcaatacga gcgcagcgtc gccgccgcgg tagttgagcg
     9241 ttgcgcgcgc cccgaggcgg tcgacgagac gcgcgcgcgc acctggctgg accgcctctt
     9301 tccgacccca gccgatgctg cggcgcgtaa ggacgccatc gactggcaga agctcgcctg
     9361 cgcgatcgcg ctgcgcgggc ggctgagcat cctcaccggc ggccccggca ccggcaagac
     9421 ctacaccgcc gcgcgcctgc tcgccctgct gctcgccacc cacccggcgc ccgagcgcct
     9481 gcgcatcgcg ctcgccgcgc ccaccggcaa ggccgccgcg cgcctgcgcc aggccatcga
     9541 cggctcgctg caggccctgc agcacagcct gggcgcacac ctcgacctcg ccgcgctgac
     9601 ccgccgcatc ggcgcggcgc gcaccctgca tgcgctgctc ggcgcccgcc ccgacacccg
     9661 gcgcttccgc caccacgccg gcaacccgct cgatgtcgac gtggtgatcg tcgacgaggc
     9721 ctcgatggtg cacctggaga tgatggccgc gctgctcgaa gcgttgccgc ccggcgcgcg
     9781 cctggtgctg ctcggcgaca aggaccagct cgcctcggtc gaggccggcg cggtgctcgg
     9841 cgacctctgc cgcgacgccg aggcgggacg ctacgacgcc gagaccgcgc gctacctgct
     9901 cgccaccacc ggcgaggccc tgcccgcgcg ctacctggcg gctgcaggca cggcgcccgc
     9961 gctcgcccag cacaccgtta tgctgcgcgt aagccggcgc ttcgagggcc cgatcggcgc
    10021 gctcgcgctc gcggtgaacg cggcgcgcga cccggccctg cccgcgcgcc tgctgcgcga
    10081 ggacgccagc ggtgcgctgc acggagtcga gggcgggccg gtggcggcgg tgatcgcgct
    10141 cgcgctcgac ggccgcgagg gcgcgtccgc ctgttaccgc gactatctgg agcggctcgc
    10201 gcgcggtccc gcgggcaagg acggcgcggc gcacgcggcg tgggcggcgg acatcctgaa
    10261 ggccttcgac cgcttccgcg tgctgtgcgc ggtgcgcgag ggcgactggg gcgtggccgg
    10321 gctcaaccgc gcgatcgagc acgcgctcgc acgcgcgcgc ctgctgtcgc cgcgcggcag
    10381 ctggtatccg gggcgcccgg tcatggtcac ccgcaacgac cccgcgctcg gcgtcttcaa
    10441 cggcgacatc ggcatcaccc tgccggcggc cgagggtggc ggcctgcgcg tgcatttcct
    10501 cgacggcgag gccttgcgct cggtcgcggt gagccgcctc gcccacgtcg agacggcgtt
    10561 cgcgatgacg gtgcacaaga gccagggctc ggagttcgag cacacggcgc tggtgctggc
    10621 cgcgcagagt ggcaacgtgc tcacgcgcga gctgatctac accgcgatca cgcgcgcacg
    10681 caaggccttc agcctggtgg ccgaacgcga gggcttgctg gagaatggcg tgttgcaggc
    10741 gacccggcgc gagagcgggt tgctgggctt ccaaggaacg acgggatgaa gaagacggga
    10801 tccgcggcgc gctcgctggc actctgcctg cttgcggcct tgtgcctcgg cggctgcgcc
    10861 gtcaccgccg tggccggcgc cgtggtcacg gtcgccgcca ccgccgtcag cgtcaccgcg
    10921 accgtggtcg agaccacggt ggatgtcgcc gccgcgggtg tggaagcggt ggtgggggaa
    10981 gacgaggagg agcaagcgga agaatgagcg gcgacgtcgt gcacgcaggt cgcatcccga
    11041 accgtttcat tcgcgcctgc cggcgctcct acatgaaacc caccacggcc acacgcacgc
    11101 caccgcaacc cggctcgatg caggcgcgag gacggcggtg gagtgctgtg cgcgccattt
    11161 gccggaccgc cgggtgcgca gctgccgcag ttcctacagg cgggccggga cgcgcggcgg
    11221 ttcatgtagg agcgccggca ggcgcgaagg cggcgatgga gtgccgcttg cgcgtcattt
    11281 gccggaccgc caggtgcgca gctgccgcag ctcctacagg cgggccggga cgcgcggcgg
    11341 ttcatgtagg agcgccggca ggcgcgnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11461 nnnnnnaagg cggcggtgga gtgccgcttg cgcgtcattt tccggaccgc caggttcgca
    11521 gctgccgcag ctcctacagg gggccgggac gcgtggcggt tcatgtagga gcgccggcag
    11581 gcgcgaaggc ggcgg
//
LOCUS       DAOTIN010000105        11507 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_6679_length_11507_cov_8.796018, whole genome shotgun sequence.
ACCESSION   DAOTIN010000105 DAOTIN010000000
VERSION     DAOTIN010000105.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 11507)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 11507)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11507
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6679_length_11507_cov_8.796018"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..788
                     /locus_tag="P5537_13255"
     CDS             <1..788
                     /locus_tag="P5537_13255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HRV79051.1"
                     /translation="EPINPAAWEWYYENVGGGRCPIVDTFWQTETGAHMITPMPGATP
                     MIPGSCTLPFPGIMAAVVDETGTEVPWGQGGILVVTKPWPSMIRTVWGDPDRFKKTYY
                     PEDFKGKLYLAGDGAIRDAETGYFTITGRIDDVLNVSGHRMGTMEIESALVAHEKVAE
                     AAVVGRPDDLTGEAIVAFVVLKGARPTGEEAAKVVKELQNWVGHEIGPIAKPKDIRFG
                     ENLPKTRSGKIMRRLLRQLAKGEDVTQDTSTLENPHILEQLKG"
     gene            985..1182
                     /locus_tag="P5537_13260"
     CDS             985..1182
                     /locus_tag="P5537_13260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79052.1"
                     /translation="MRKGLAGQRLVAVFIAGLVLLNYPILSLFDRPQTVLGLPLLHVY
                     LFAVWIALILVVAWIVERGAR"
     gene            1196..3937
                     /locus_tag="P5537_13265"
     CDS             1196..3937
                     /locus_tag="P5537_13265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HRV79053.1"
                     /translation="MLPGWLIVGASFAYLLLLFAVAYFGDRRADAGRSVIDNPWVFSL
                     SLAVYCTAWTYFGSVGRAASGGPWFLPTYLGPTLGLTLAWLVVLKMIRIARSYRVTSI
                     ADFVASRYGKSHLLGGLVTLIAVVGIVPYIALQLKAISSGYALLVGEHDTLFRIESQS
                     GWWQDGTLYIALALAAFTVLFGTRHLDTTERHEGMVAAIAFESVVKLLAFLAVGVYVT
                     YWLYDGFGDLYARAAAVPELQRLLAFDGAGRLGYGGWFAHVLLAMLSIIFLPRQFQIA
                     VVENVNEQHLRRATWVFPAYLLAINLFVIPVAIGGLLHFGSGTVDPDTFVLTLPLAHG
                     QNALALLVFIGGLSAATGMVIVEAIALSTMVCNDLVMPMLLRSRRLDLARERDLTGLL
                     LGIRRGAIVVLLLLGYLYFRLAGEAYALVSIGLISFAAVAQFAPVVIGGMYWRGGTRE
                     GALAGLLAGFAVWVYTLLLPSFAKSGWLDPGFLEHGVLGLGWLRPEQLFGLTGLDNIS
                     HALFWSLLANIGCYVAVSMLRVPTGPEATQGALFVDVFRRGDAPPASFWRTGAEAGEL
                     VPLVARFLGQRRTEEAFGAYARSHGLQRVSELKADPELVHFAETLLAGAIGSASARVM
                     VSTVVQAEPLGLGEVMDILDEASQVRAYSHKLEEKSRALEAATAELRAANERLQELDR
                     LKDDFMSSVTHELRTPLTSIRALSEMMLDDPDIDVEDRQRFLGIIVSETVRLSRLVNQ
                     VLDMAKIESGHAEWHNTDIDLCELVRHSGDATLQLFRDRGAELHLHLPESVPTLRADH
                     DRLLQVMLNLLSNAAKFVPTGSGRVDVTLSCDGERCRVAVKDNGPGIEPAQQPVVFEK
                     FRQGGDERSRPQGTGLGLPISRQIVEHFGGRLWLESVPGEGATFSFELPLKSAAGEG"
     gene            3968..4336
                     /locus_tag="P5537_13270"
     CDS             3968..4336
                     /locus_tag="P5537_13270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV79054.1"
                     /translation="MDKKVLIADDEQNIVISLEFLMKREGYQVEVANDGEEAVRRIRA
                     SRPDLVLLDVMMPKKSGFEVCQEIRSDPEMAGIRILMLTAKGRDTEVAKGLALGADAY
                     MTKPFSTRELVDKVRSLLEH"
     gene            4340..6631
                     /locus_tag="P5537_13275"
     CDS             4340..6631
                     /locus_tag="P5537_13275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HRV79055.1"
                     /translation="MQARTRFMLAVVVLFLLMTGPFLLTALIVWVETAGEAREMLVKV
                     LSPHLTLGTLLTAMGFAAGVGVVRVLFRQYVQGLLRMSENLRLMLGANRGFRVQPEGP
                     PEVQQLAVAANELASQRDALLEDVEAQIARAKASVELEKDRLAALMSELTQSVVVCNL
                     DGRVLLYNNRARAQFRALSEAPGVAGGGELIGLGRSIYGVFERNLIAHALDTIQQRLR
                     RGATQAQANFVTTTRAGQLLRVQMAPVLSLAAPALAAAAEGETAGGQGAEQGDAGVVG
                     AADETLPATAAAAAAEGAPERTLTGFILMLDNITRNFETESRRDQMLHNLTEGSRASL
                     ANVRAAADMLEFEDLPDEMRTRFRKVVRDEVQSMSQRLDQTANEFADSLKARWPLEEM
                     FGADLIAAAQRRIEARIGLPTKLEEVDETLWVKVDSFSLIQAITYLASRLSDEFEVRE
                     VRFRLTAAGRLVHLDLIWSGQAMSTETVMSWELEPMKIEDESSPLTVRDVIDRHDGEM
                     WLEREKVRHRAFFRILLPAATPQEQAEAETYLRGESRPEYYDFDLFAWSEKSHALDDR
                     LLSELSYTVFDTETTGLNPSQGDEIIQIGATRILNGKLLRAESFEQLVDPERPLAPES
                     AKIHGITSEMLRGQPTIDKVLPAFHAFSADTVLIAHNAAFDMRFLQLKEEQTGLRFDH
                     PVIDTLLLSAVVHPNQESHRLEAIAERLGLTIIGRHTALGDAIVTAEVFLKLIPLLAE
                     KGIRTLRDAREAAEKTYYARIKY"
     gene            6669..8714
                     /locus_tag="P5537_13280"
     CDS             6669..8714
                     /locus_tag="P5537_13280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation acetate symporter"
                     /protein_id="HRV79056.1"
                     /translation="MRRNLGFARQLRRYYGIYTLGFAVFVVLLAIGESMGLSQQLIGH
                     VFLFVTIAIYATIGVLSRTSDVSEYYVAGRRVPALFNGMATAADWMSAASFIGLAGTL
                     YFSGFEGLAFVTGWTGGFVLVALLLAPYLRKFGQYTIPDFLGARYQGNVARLVGLSAA
                     VLASFVYLVAQIYGVGLVTSRFVSVEFEIGLFIGLAGILVCSFLGGMRAVTWTQVAQY
                     VILIIAYLVPVVILSYKLTGIPIPQAVYGTVLQQISAREDALFEAPSEREVRDLYTAR
                     AQDYADKIAALPASLEDERRRMIEELNGMRLGNAPARDIALAERALRDLPRTPAQASE
                     AWQRARAEALERARPPPRHAEAHPGATADESATARNNFLALMFVLMVGTAALPHILMR
                     YYTTPGVMEARRSVLWSLFFIFLLYVTAPAYAVFAKWEVYNNLVGSSIAILPDWVASW
                     GRVGLVRIEDLNGDGILQLAELRLNTDVIVLATPEIAGLPYVVSGLVAAGGLAAALST
                     ADGLLLTISNALSHDLYYKVINPQATTHRRLVISKSQLLVVAVVAAWVASMRPDNILF
                     MVGLAFSIGGSAFFPALVLGIFWKRANRPGAVAGMLAGLAVTVFYVVHTHPFFGGSMV
                     NAWFDINSISAGVFGVPLGFATIVVVSLLTKPPPQEIQDLVDYVRYPDIPGQNRPHH"
     gene            8785..11376
                     /gene="clpB"
                     /locus_tag="P5537_13285"
     CDS             8785..11376
                     /gene="clpB"
                     /locus_tag="P5537_13285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HRV79057.1"
                     /translation="MRFDKLTTKFQQALADAQSIAVGNDQQFIEPLHVVQALLDQDDG
                     GSVSLLQRAGVNVPPLKTAVGRAIGRLPKVEGHGGEVSIGRDLNNLLNVTDREAQKRG
                     DQFIASEMFLLALCDDKGEAGRLLKENGLARKALEAAIEAVRGGANVGTQDAEGQRES
                     LAKYCLDLTERARSGKLDPVIGRDDEIRRAIQILQRRTKNNPVLIGEPGVGKTAIVEG
                     LAQRIVNDEVPETLKGKRVLSLDMAALLAGAKYRGEFEERLKAVLKEIAQEEGRIIVF
                     IDELHTMVGAGKAEGAIDAGNMLKPALARGELHCIGATTLDEYRKYIEKDAALERRFQ
                     KVLVEEPSVEATIAILRGLQEKYEIHHGVDITDPAIVAAAELSNRYITDRFLPDKAID
                     LIDEAAARIKMEIDSKPEVMDKLDRRMIQLKIEREAVKKEKDEASQKRLQLIEEELAK
                     LQREYNDLEEIWKAEKSKAAGSAHIKEEIDALRAQMAEFQRKGQLDKVAELQYGKLPQ
                     LEGQLKMAEQAGENATPNKLLRTQVGAEEIAEVVSRATGIPVSKMMQGEREKLLKMED
                     KLHERVVGQDEAVRLVADAIRRSRAGLSDENRPYGSFLFLGPTGVGKTELCKTLASFL
                     FDSEEHLIRIDMSEFMEKHSVARLIGAPPGYVGYEEGGYLTEQVRRKPYSVILFDEVE
                     KAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVIVMTSNLGSQMIQAMAGDDYGVIKL
                     AVMAEVKTYFRPEFINRIDEVVVFHALDEKHIAGIAKIQLQYLEKRLARLEMGMEISD
                     AALAELATAGFDPVFGARPLKRAIQERIENPLAKAILEGRFAAKDRIRVDAEGGQLVF
                     QRATAPV"
BASE COUNT         1802 a         3988 c         3899 g         1818 t
ORIGIN      
        1 gcgagccgat caacccggcg gcctgggagt ggtactacga gaacgtcggc ggcggacgct
       61 gcccgatcgt cgataccttc tggcagaccg agaccggcgc gcacatgatc accccgatgc
      121 cgggtgcgac cccgatgatc ccgggttcgt gcacgctgcc cttcccgggc atcatggccg
      181 cggtggtcga tgagaccggc accgaggtgc cctggggcca gggcggcatc ctggtggtca
      241 ccaagccgtg gccgtcgatg atccgcacgg tgtggggcga ccccgaccgc ttcaagaaga
      301 cctactaccc cgaggacttc aagggcaagc tctacctcgc gggcgacggc gccatccgcg
      361 acgccgagac cggctacttc accatcaccg gccgcatcga cgacgtgctc aacgtctccg
      421 gccaccgcat gggcacgatg gagatcgagt cggccctggt cgcgcacgag aaggtggccg
      481 aggccgccgt ggtcggccgc ccggacgacc tcacgggcga ggcgatcgtt gccttcgtgg
      541 tgctgaaggg cgcgcgtccc accggcgagg aagccgccaa ggtggtcaag gaactgcaga
      601 actgggtcgg ccacgagatc gggccgatcg ccaagccgaa ggacatccgc ttcggcgaga
      661 acctgcccaa gacccgctcc ggcaagatca tgcgccgcct gctgcgccag ctcgccaagg
      721 gcgaggatgt cacccaggac acctcgacgc tcgagaaccc gcacatcctc gagcagctca
      781 agggctgatg cagtgcaggc cgggcgcccc gcgcccggcc gctcctgaac gacaggagga
      841 agccggccag cgagccggtg ccggggggag accgggtacg cgcaaggcgt gcccctgttc
      901 gtgcgtcgcg ccgaccctgc cgcaaagagc agggcggtgc tgcgccattt cgtttgccgt
      961 ggctcgtttc atgggagcga caggatgcgc aagggtctgg ccgggcagcg cctggtggcc
     1021 gtgttcatcg ccggcctggt gttgctgaac tatcccattc tgtccctgtt cgaccgcccg
     1081 cagaccgtcc tcgggctgcc gctgctccac gtctatctgt tcgcggtgtg gatcgcgctg
     1141 atcctggtcg tggcgtggat cgtcgagcgc ggggcgcgct gatgcggagg tcgtgatgct
     1201 gccgggctgg ctgatcgtcg gcgcctcgtt cgcctacctg ctgctgctgt tcgcggtggc
     1261 ctacttcggc gaccggcgcg cggacgccgg gcgctcggtc atcgacaatc cctgggtttt
     1321 cagtctatcg ctcgcggtgt attgcaccgc gtggacctat ttcggcagcg tcggtcgcgc
     1381 cgcctcgggc gggccgtggt tcctgccgac ctatctcggg cccacgctgg gcctcaccct
     1441 ggcctggctg gtcgtgctca agatgatccg catcgcgcgc agctaccggg tcacctcgat
     1501 cgccgacttc gtcgcctcgc gctacggcaa gagccacctg ctcggcgggc tggtcacgct
     1561 gatcgcggtg gtgggcatcg tgccctacat cgcgctgcag ctgaaggcga tctccagcgg
     1621 ctacgcgctg ctggtgggcg agcacgacac gctgttccgc atcgagagcc agtccggctg
     1681 gtggcaggac ggcacgctct acatcgcgct cgcgctcgcc gccttcaccg tgctgttcgg
     1741 cacccgccac ctcgacacca ccgagcgcca cgagggcatg gtggcggcga tcgccttcga
     1801 gtcggtcgtc aagctgctgg ccttcctcgc ggtcggcgtc tacgtcacct actggctcta
     1861 cgacggcttc ggcgacctct acgcgcgcgc cgcggcggtg cccgagctgc aacgcctgct
     1921 cgccttcgac ggcgccggcc ggctcggcta cggcggctgg ttcgcccacg tcctgctggc
     1981 gatgctgtcg atcatcttcc tgccgcggca gttccagatc gcggtggtgg agaacgtcaa
     2041 cgagcagcac ctgcgccgcg ccacctgggt ctttcccgcc tacctgctgg cgatcaacct
     2101 cttcgtgatc ccggtcgcga tcggcgggct gctgcatttt ggcagcggca cggtggaccc
     2161 ggacaccttc gtgctgaccc tgccgctcgc gcatgggcag aatgcgctcg ccttgctcgt
     2221 gttcatcggc ggcctgtccg cagccaccgg catggtgatc gtggaggcga tcgcgctgtc
     2281 cacgatggtg tgcaacgacc tcgtgatgcc gatgctgctg cgcagccggc ggctcgacct
     2341 cgcgcgcgag cgcgacctca ccgggctcct gctcggcatc cgccgcggcg cgatcgtggt
     2401 gctgctgctg ctcggctatc tctacttccg cctcgccggc gaggcctacg cgctggtcag
     2461 catcggcctc atcagcttcg ccgcggtggc gcagttcgcc ccggtggtga tcggcggcat
     2521 gtattggcgt ggcggcaccc gcgagggcgc gctcgccggc ctgctcgcgg gcttcgcggt
     2581 gtgggtctac acgctgctgc tgccgtcgtt cgccaagtcg ggctggctcg atccgggctt
     2641 cctcgagcac ggcgtgctcg gcctaggctg gctcaggccc gagcagctct tcgggctcac
     2701 cggcctggac aacatcagcc acgcgctgtt ctggagcctg ctcgccaaca tcggctgcta
     2761 cgtcgcggtg tcgatgctgc gcgtgccgac cggaccggag gccacccagg gcgcgctctt
     2821 cgtcgatgtg ttccggcgtg gcgacgcgcc gccggccagc ttctggcgca ccggcgccga
     2881 ggccggcgag ctggtgccgc tggtggcgcg cttcctcggc cagcgccgta ccgaggaggc
     2941 cttcggcgcc tacgcgcgct cgcatggcct gcagcgggtc tccgagctca aggccgatcc
     3001 cgagctggtc cacttcgccg agacccttct cgccggcgcc atcggcagcg cctcggcgcg
     3061 ggtgatggtg tcgaccgtgg tgcaggcgga gccgctcggg ctcggcgagg tcatggacat
     3121 cctcgacgag gcctcgcagg tccgcgccta ctcgcacaag ctcgaggaga agtcgcgcgc
     3181 gctcgaggcc gcgaccgccg agctgcgcgc cgccaacgag cgcctgcagg agctcgaccg
     3241 cctgaaggac gacttcatgt cctcggtgac gcacgagctg cgcacgccgc tgacctcgat
     3301 ccgcgcgctc tccgagatga tgctcgacga tcccgacatc gacgtcgagg atcgccagcg
     3361 cttcctgggc atcatcgtgt cggagacggt gcgcctgtcg cgcctggtga accaggtgct
     3421 cgacatggcc aagatcgaat ccggccacgc cgagtggcac aacaccgaca tcgacctgtg
     3481 cgagctcgtg cgccactccg gcgacgccac gctgcagctc ttccgggacc gcggcgccga
     3541 gctgcacctg cacctgccgg agtcggtgcc gacgctgcgt gccgatcacg accgcctgct
     3601 gcaggtgatg ctcaacctgc tgtcgaacgc ggcgaagttc gtgcccacgg gcagcggtcg
     3661 ggtggacgtg acgctgagct gcgacggcga gcgctgtcgc gtcgcggtga aggacaacgg
     3721 accggggatc gagccggccc agcagccggt tgtattcgag aagttccgcc agggcgggga
     3781 cgagcgctcg cggccgcagg gcaccggcct gggcctgccg atcagccgcc agatcgtcga
     3841 gcacttcggc ggtcggctgt ggctggagtc cgtgccgggc gagggcgcga cattctcctt
     3901 cgagctgccg ctgaagtcgg cggcgggcga gggatgacat agaatatcgg gcggggagga
     3961 gacgctgatg gacaagaaag tactgattgc cgacgacgaa cagaacatcg tcatttcgct
     4021 ggagttcctc atgaagcgcg agggctatca ggtcgaggtg gccaacgacg gcgaggaggc
     4081 cgtgcgccgg atccgcgcct cgcggcccga tctggtgctg ctcgacgtca tgatgccgaa
     4141 aaagagcggc ttcgaggtct gccaggagat ccgctccgat cccgagatgg cggggatccg
     4201 gatcctgatg ctcaccgcca agggccgcga caccgaggtc gccaagggcc tggcgctcgg
     4261 tgccgacgcc tacatgacca agcccttctc cacccgcgag ctggtggaca aggtgcgcag
     4321 cctgctggag cactgagcca tgcaggcacg tacgcgattc atgctcgcgg tcgtcgtgct
     4381 gttcctgctg atgaccggac ccttcctgct cactgcgctg atcgtctggg tcgagaccgc
     4441 aggcgaggcg cgcgaaatgc tggtgaaggt gctgtcgcct cacctcacgc tcggcacgct
     4501 gctcaccgcg atgggcttcg cggccggcgt gggcgtggtg cgggtgctct tccgccagta
     4561 cgtacagggg ctgctgcgca tgtcggagaa cctgcgcctg atgctcggcg ccaaccgcgg
     4621 cttccgcgtg cagcccgagg ggccgcccga ggttcagcaa ctcgcggtcg ccgccaacga
     4681 gctcgccagc cagcgcgatg cgctgctgga ggacgtggag gcgcagatcg cgcgcgccaa
     4741 ggcctcggtc gaactcgaga aggaccgcct cgccgcgttg atgtccgagc tcacccagag
     4801 cgtcgtggtg tgcaacctcg acggccgcgt gctgctctac aacaaccgtg cgcgcgcgca
     4861 gttccgcgcg ctctccgagg ccccgggcgt ggccggcggc ggcgagctga tcggcctcgg
     4921 gcgttcgatc tacggcgtat tcgagcgcaa cctgatcgcg cacgcgctcg acaccatcca
     4981 gcagcgcctg cgccgcggcg ccacgcaggc gcaggccaac ttcgtcacca ccacccgggc
     5041 aggccagctg ctgcgcgtgc agatggcgcc ggtgctgtcg ctggcggcgc cggcccttgc
     5101 ggccgcggcg gagggcgaga ccgcgggcgg acagggcgcg gagcagggtg acgcgggtgt
     5161 ggtcggcgcg gcggacgaga ccttgccggc gacagcggca gccgcggctg cggagggcgc
     5221 cccggagcgc acgctcaccg gcttcatcct catgctcgac aacatcacgc gcaacttcga
     5281 gaccgagtcg cgccgcgacc agatgctgca caacctcacc gagggcagcc gcgcctcgct
     5341 cgccaacgtg cgcgcagcgg ccgacatgct ggaattcgag gacctccccg acgagatgcg
     5401 cacgcgcttc cgcaaggtgg ttcgcgacga ggtgcagtcg atgagccagc gcctcgacca
     5461 gaccgccaac gagttcgccg attcgctgaa ggcgcgctgg ccgctcgagg aaatgttcgg
     5521 cgccgacctg atcgccgcgg cgcagcgccg catcgaggcc cgcatcggcc tgcccaccaa
     5581 gctcgaggag gtcgacgaga cgctgtgggt gaaggtcgac agcttctcgc tgatccaggc
     5641 catcacctac cttgccagcc ggctgtcgga cgagttcgag gtgcgcgagg tgcgcttccg
     5701 gctcaccgcg gccggtcgcc tggtgcacct cgatttgatc tggtccgggc aggcgatgag
     5761 caccgagacg gtgatgagct gggagctcga gccgatgaag atcgaggacg agagcagccc
     5821 gctcaccgta cgcgacgtga tcgaccgcca cgacggcgag atgtggctcg agcgcgagaa
     5881 ggtgcgccac cgcgccttct tccgcatcct gctgccggcg gcgacgcccc aggagcaggc
     5941 cgaggccgag acctacctgc gcggcgagag ccggcccgag tactacgact tcgacctctt
     6001 cgcctggtcg gagaagtccc acgcgctcga cgaccgcctg ctctccgagc tcagctacac
     6061 ggtgttcgac accgagacca ccgggctcaa cccctcgcag ggcgacgaga tcatccagat
     6121 cggcgcgacc cgcatcctca acggcaagct gctgcgcgcc gagtccttcg agcagctggt
     6181 ggacccggag cgtccgctcg cacccgagtc ggcgaagatt cacggcatca cctccgagat
     6241 gctgcgcggc cagcccacca tcgacaaggt gctgcccgcc ttccacgcct tctccgccga
     6301 caccgtgctg atcgcgcaca acgccgcctt cgacatgcgc ttcctgcagc tcaaggaaga
     6361 acagaccggg ctgcgcttcg atcacccggt gatcgacacc ctgctgctgt cggcggtcgt
     6421 gcaccccaac caggagtcgc accgcctgga ggcgatcgcc gagcgcctcg ggctgaccat
     6481 catcgggcgt cataccgcgc tcggtgacgc gatcgtgacc gccgaggtct tcctcaagct
     6541 gatcccgctg ctcgccgaga agggcatccg cacgctgcgt gacgcgcgcg aggccgccga
     6601 gaagacctac tacgcgcgga tcaagtactg atgacccggg cgcgcgggcc gagcggagag
     6661 cgttcccctt gaggcgcaac ctcggcttcg cgcgccagct gcgccgctac tacgggatct
     6721 ataccctcgg cttcgcggtc ttcgtcgtgc tgctggcgat cggcgagagc atggggcttt
     6781 cgcagcagct catcggccac gtcttcctgt tcgtcacgat cgcgatctac gccaccatcg
     6841 gcgtgctctc gcgcacctcc gacgtttccg agtactacgt cgccgggcgt cgcgtgccgg
     6901 cgctgttcaa cggcatggcg accgctgccg actggatgag cgcggcgtcc ttcatcgggc
     6961 tggccggaac cttgtacttc agcggcttcg agggcctggc cttcgtgacc ggctggaccg
     7021 gcggcttcgt gctggtggcc ctgctgctcg cgccctacct gcgcaagttc ggccaataca
     7081 ccatcccgga cttcctcggc gcgcgctacc agggcaacgt cgcccgcctg gtcggcctct
     7141 ccgccgcggt gctggcgagc ttcgtctatc tggtggcgca gatctacggc gtcggcctgg
     7201 tgaccagccg cttcgtcagc gtggagttcg agatcggact cttcatcggg ctggccggca
     7261 tcctggtgtg ctccttcctc ggcggcatgc gcgcggtgac ctggacccag gtggcgcagt
     7321 acgtgatcct gatcatcgcc tacctggtgc ctgtggtgat cctgtcctac aagctcaccg
     7381 gaattccgat cccgcaggcg gtctacggga cggtgctgca gcagatcagc gcgcgtgagg
     7441 acgcgctctt cgaggctccc tccgagcgcg aggtgcgcga tctctacacc gcgcgcgcgc
     7501 aagactacgc cgacaagatc gctgcgctgc ccgcctcgct cgaggacgag cgccggcgca
     7561 tgatcgagga gctcaacggc atgcgcctgg gcaacgcgcc ggcgcgcgac atcgcgcttg
     7621 ccgagcgcgc cctgcgtgac ctgccgcgca cgccggcgca ggcaagcgag gcctggcagc
     7681 gcgcccgcgc cgaggccctc gagcgcgccc gaccgccgcc gcgccacgcc gaggcgcatc
     7741 cgggcgccac cgcggacgag tccgccaccg cgcgcaacaa cttcctcgcg ctgatgttcg
     7801 tgctcatggt gggtacggcg gcgctgccgc acatcctgat gcgctactac accacgcccg
     7861 gcgtcatgga ggcgcgtcgc tcggtgctgt ggtcgctgtt cttcatcttc ctgctctacg
     7921 tcaccgcgcc ggcctacgcc gtgttcgcca agtgggaggt ctataacaac ctggtcggct
     7981 cgagcatcgc gatcctgccc gactgggtgg cgtcctgggg cagggtgggg ctggtgcgca
     8041 tcgaggacct caacggcgac ggcatcctgc aactggccga gctgcgcctc aataccgacg
     8101 tgatcgtgct cgccacgccg gagatcgccg gcctgcccta cgtcgtctcg ggcctggtcg
     8161 cggcgggggg gctggccgcc gcgctctcca ccgccgacgg tctgctgctg acgatctcga
     8221 acgcgttgtc gcacgacctc tactacaagg tgatcaatcc ccaggccacg acccaccgcc
     8281 ggctggtgat ctccaagtcg cagctgctgg tggtggcggt ggtggcggcc tgggttgcgt
     8341 cgatgcggcc ggataacatc ctcttcatgg tcggcctggc gttctcgatc ggcggctcgg
     8401 ccttcttccc ggcgctcgtg ctgggcatct tctggaagcg cgccaatcgt cccggcgcgg
     8461 tcgccggcat gctcgcgggg ctggcggtca cggtcttcta cgtggtgcac acccacccct
     8521 tcttcggcgg ctcgatggtg aacgcctggt tcgacatcaa ctcgatctcg gcaggtgtgt
     8581 tcggcgtgcc gctcggcttc gcaaccatcg tcgtggtcag cctgctgacc aagccgccgc
     8641 ctcaggagat ccaggacctg gtcgactacg tgcgctaccc cgacattcca ggtcagaacc
     8701 ggccgcatca ctgagcgggt acttgaagcg cggcggatgc gccccacata gggtttagtt
     8761 caacgaatcc cgaggatcgt ccccatgcgc ttcgacaagc tcaccaccaa gttccagcag
     8821 gccctggccg atgcacagag catcgccgtg ggcaacgatc agcaattcat cgagccgctg
     8881 cacgtggtgc aggccctcct tgatcaggac gacggcggca gcgtgtcgct gctgcagcgc
     8941 gccggcgtga acgtgccgcc gctcaagacc gctgtggggc gcgccatcgg ccgcctgccc
     9001 aaggtcgagg gccatggcgg cgaggtcagc atcggccgcg acctcaacaa cctgctcaac
     9061 gtcaccgacc gcgaagcgca gaagcgcggc gaccagttca tcgccagcga gatgttcctg
     9121 ctcgccttgt gtgacgacaa gggcgaggcc ggccgcctgc tcaaggaaaa cgggctcgcg
     9181 cgcaaggcgc tggaggccgc catcgaggcc gtgcgcggtg gcgccaatgt cggcacccag
     9241 gacgccgagg gccagcgcga gtcgctcgcc aagtactgcc tcgacctcac cgagcgtgcg
     9301 cgcagcggca agctcgaccc ggtgatcggc cgcgacgacg agatccgccg cgccatccag
     9361 atcctgcagc gccgtaccaa gaacaacccg gtgctgatcg gcgagccggg cgtgggcaag
     9421 accgcgatcg tcgagggcct ggcgcaacgc atcgtcaatg acgaggtgcc cgagaccctg
     9481 aagggcaagc gcgtgctgtc gctcgacatg gcggcgctgc tcgccggcgc caagtaccgc
     9541 ggcgagttcg aggagcgcct gaaggcggtg ctgaaggaga tcgcccagga agagggccgc
     9601 atcatcgtct tcatcgacga gctccacacc atggtgggcg ccggcaaggc cgagggcgcg
     9661 atcgacgccg gcaacatgct caagcccgcg ctcgcgcgcg gcgagctgca ctgcatcggc
     9721 gccaccacgc tcgacgaata ccgcaagtac atcgagaagg acgccgcgct cgagcgccgc
     9781 ttccagaagg tgctggtcga ggagcccagc gtcgaggcca ccatcgccat cctgcgcggc
     9841 ctgcaggaga aatacgagat ccaccacggc gtcgacatca ccgacccggc catcgtcgcc
     9901 gcggccgagc tgtcgaaccg ctacatcacc gaccgcttcc tgccggacaa ggcgatcgac
     9961 ctgatcgacg aggcggctgc acgcatcaag atggagatcg actccaagcc cgaggtcatg
    10021 gacaagctcg accgccgcat gatccagctc aagatcgagc gcgaggcggt gaagaaggag
    10081 aaggacgagg cctcgcagaa gcgcctgcag ctcatcgagg aagagctcgc caagctgcag
    10141 cgcgagtaca acgacctcga ggagatctgg aaggccgaga agtccaaggc cgccggctcg
    10201 gcccacatca aggaagagat cgacgcgctg cgcgcgcaga tggccgagtt ccagaggaag
    10261 ggccagctcg acaaggtcgc cgagctgcaa tacggcaagc tgccgcagct cgaaggccag
    10321 ctgaagatgg ccgagcaggc cggcgagaac gccacgccca acaagctcct gcgcacccag
    10381 gtcggcgccg aggagatcgc ggaggtcgtc tcgcgcgcca ccggcatccc ggtgagcaag
    10441 atgatgcagg gcgagcgcga gaagctgctc aagatggagg acaagctgca tgagcgcgtg
    10501 gtcggccagg acgaggccgt gcgcctggtc gccgacgcca tccggcgttc gcgcgccggc
    10561 ctttcggatg agaaccggcc ctatggttcc ttcctcttcc tcggccccac cggcgtgggc
    10621 aagaccgagc tgtgcaagac gctggcgagc ttcctgttcg actccgagga gcacctgatc
    10681 cgcatcgaca tgagcgagtt catggagaag cactcggtcg cgcggctgat cggcgcgccc
    10741 ccgggctacg tcggctacga agagggcggc tacctgaccg agcaggtgcg gcgcaagccc
    10801 tacagcgtga tcctgttcga cgaggtcgag aaggcgcatc cggacgtgtt caacgtgctg
    10861 ctgcaggtgc tcgacgacgg ccgcatgacc gacggtcagg ggcgcaccgt ggacttcaag
    10921 aacaccgtga tcgtgatgac gtccaacctc ggcagccaga tgatccaggc catggcgggc
    10981 gacgactacg gcgtgatcaa gctcgcggtg atggcggagg tgaagacgta tttccgcccg
    11041 gagttcatca accgcatcga cgaggtggtg gtgttccacg cgctcgacga gaagcacatc
    11101 gccggcatcg cgaagattca gctgcagtac ctcgagaagc gcctggcgcg gctggaaatg
    11161 ggcatggaga tcagcgatgc ggcgctcgcc gagctggcga ccgccggctt cgacccggtg
    11221 ttcggggcgc ggccgctcaa gcgtgcgatc caggagcgca tcgagaaccc gctcgcgaag
    11281 gcgatcctcg aaggccggtt tgccgccaag gaccgcatcc gcgtcgatgc cgagggtggg
    11341 cagctggtgt tccagcgcgc tacggccccc gtttgagccg gaacgccctg caggagctgc
    11401 ggcagctgcg aacatggcag tcggggtatc gacgcgcgtc gccttcggtc ggcgccgctt
    11461 tcgcgcctgc cggcgctcct acacaaaccg cctcgcgtcc cggccgc
//
LOCUS       DAOTIN010000106        11474 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_6704_length_11474_cov_9.650670, whole genome shotgun sequence.
ACCESSION   DAOTIN010000106 DAOTIN010000000
VERSION     DAOTIN010000106.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 11474)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 11474)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11474
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6704_length_11474_cov_9.650670"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            12..1910
                     /locus_tag="P5537_13290"
     CDS             12..1910
                     /locus_tag="P5537_13290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="HRV79058.1"
                     /translation="MTRETASPVALSTLRGLLPFLRPYRARVVLAFVLLCLGSAAILV
                     VPLAFRDLIDAGFGGVSAGGAAAQGGAGLFGAQGLDGRFVALFALAVFWAAAVAARYY
                     TVSWIGERVTADLRSAVYARVLRQSPQFFETLQTGEVLSRLTGDTTLVQTVVGSSISL
                     GLRSLFQFVGGMVMLAVTSVQLFGLIFGLMALLALPITLIGRRVRSLSREAQDRIADA
                     SALAGEILNAMPTVQAFGQEANEAARFAARAETGFATAVRRTRVRAALTGLIIAAVMG
                     TIIFVLWIGARQVQAGALSVGELGAFVIYAALVAGGAGTLAEVWGDVMRAAGATGRLL
                     ELLRAEPAIRDAGVVERMREDGGGGGDSRLPPLLQENSRRTPPVGAAAAANPTTAPAI
                     ELGHVVFRYPARPAVPALDGIDLRIAAGERLALVGPSGAGKTSLFQLLLRFYEAGEGH
                     IRIDGHDIRALPLRSLRARIALVPQDPVIFSASALDNIRYGRPDAGDDEVIAAARAAA
                     ADEFIARLPEGYATFLGERGTRLSGGQRQRIAIARAILKGAPILLLDEATSALDAESE
                     VLVQQGLAAAMQGRTTLIIAHRLATVQKVDRIVVMDAGRIVETGTPADLRRQGGLYAR
                     LAALQLEG"
     gene            complement(2172..>2913)
                     /locus_tag="P5537_13295"
     CDS             complement(2172..>2913)
                     /locus_tag="P5537_13295"
                     /EC_number="6.5.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003910 - DNA ligase (ATP) activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="DNA ligase"
                     /protein_id="HRV79059.1"
                     /translation="DPSIDPAGWWVSEKLDGVRASWDGSVLRFRSGRTLPAPAWFLAA
                     LPPVALDGELWLGRRRFDALSGLLRREDPEDPLWREVRYMLFELPGAPGDFDTRLARL
                     RSLADTAGAPWVQAVPQRRVADRATLQRLLDEVLAGGGEGLMLHRADAHWQPGRSEAL
                     RKLTPWLDAEARVVGYLPGKGRLQGRVGALQVETADGRRFRIGSGLSDALRANPPALG
                     ALVTYRYRELTPAGLPRFPRYLRERTLP"
     assembly_gap    2914..3013
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(3351..4184)
                     /locus_tag="P5537_13300"
     CDS             complement(3351..4184)
                     /locus_tag="P5537_13300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3025 domain-containing protein"
                     /protein_id="HRV79060.1"
                     /translation="MTDALAIPAAFAERRLFEPIAPWLARFNAPGVPSRAALDVLLAE
                     TAPAAHSGGGARIRFAAPGEDEAGYEARIFTTGEVPTREADWHDFFNALAWCAWPRTK
                     ACCNRLHLDELRARAAAGLAGRGPRRDALTQFDECGIVVVSADPELPALLAAHEWEEV
                     FWRRREALQRSTRFLVFGHGSWDQLRTPFPGLCAKALHRVVDPAWLALPAAAALAETD
                     AWLAAHLAATIGDLSPRSLAPLPLLGIPGVTTDSESAEYYRDTRQFRPKRMPARAAAD
                     A"
     gene            complement(4307..5659)
                     /locus_tag="P5537_13305"
     CDS             complement(4307..5659)
                     /locus_tag="P5537_13305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004387139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HRV79061.1"
                     /translation="MKNIKFALLLVLAALSLLWWWADPLLIQGDTYFALRTLAVNYTG
                     VLAMGTMSVAMILALRPAALEPLLGGMDKAYRLHKWLGIAGLSVGVVHWLWAKGTKWA
                     VGWGWLEKPARGPRPEQTVELFRFFQEQRGLAESIGEWAFYLFAVLAAIALIKRFPYR
                     RFVQTHRVMAAVYLALVVHGVVLLPFAYWTEPAGIVMAVLMAAGSWAALRSLAGRIGS
                     GRRAHGHIERVVQHRDNQVLEVGLRLDTPWPGHQAGQFAFVTFDEREGPHPFTISSAW
                     GGDGRMDFMIKPLGDYTRRLPATLKAGDPVRVEGPYGRFDFSGAQARQIWVAGGIGIT
                     PFVARMQARTQDEAHAGAGAGAAAPVDLFYSTSAPDEGFIARLRELAAQARVKLHVLV
                     SQRDGRLDADGICRKVPDWKLAGVWFCGPAGFGATLRDTLAARGLPAERFHQELFEMR
                     "
     gene            5862..6638
                     /locus_tag="P5537_13310"
     CDS             5862..6638
                     /locus_tag="P5537_13310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004312786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HRV79062.1"
                     /translation="MFQHSAPSPAWLQHDMERVDAIIRAHMNNDVALIRQVVEFILHG
                     AERQRPALVLATARALGHGGERPHALAAAVELIHISLALHDDVTEASGGAADGAHEAA
                     LFGNAGNILLGDLLYTSAFRMIVDLDDMEVMRVLSDATNVIAEGEVAYRELLAAPASR
                     TPEAWLDIARRRRAKLFEAGAECMAIVHGADPATRSALARVGLHVGSAHALRSEAEDA
                     ARFGIADAPARAQAEIEAAQAVVDGLALADAAALVAVVEG"
     assembly_gap    6866..6965
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(7225..7605)
                     /locus_tag="P5537_13315"
     CDS             complement(7225..7605)
                     /locus_tag="P5537_13315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004336190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79063.1"
                     /translation="MTPKLPATLAAALALSACSIQPPKVETARGVTQQTGQFEFALPS
                     GEYRCERGERLQIRRELANTVNNRIQLGWKGGQYLLVRDPSDSGLPRFEDSASGLVWI
                     DLPWKGLLLDGRTHKPLANECRAA"
     gene            complement(7756..9408)
                     /gene="gpmI"
                     /locus_tag="P5537_13320"
     CDS             complement(7756..9408)
                     /gene="gpmI"
                     /locus_tag="P5537_13320"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046537 -
                     2,3-bisphosphoglycerate-independent phosphoglycerate
                     mutase activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HRV79064.1"
                     /translation="MLQKFPAFAGVKGPVVVIVMDGYGIPKHEVGSAIDAARKPTLDR
                     LFAECPNIRLRAHGTAVGMPSDDDMGNSEVGHNAIGAGQVYAQGAALVANAIAEGVIW
                     QGEAWQQIVAGAKAGANGKAGVLHFIGLFSDGNVHSHIDHLKAMVVRAKEEGVATVRI
                     HALLDGRDVPETSALDYVVPFEAFLQDISRDGFDARIASGGGRQTITMDRYDANWPMV
                     ARGWRTHVLGEGPQFANATEAVHRLREKHPGTIDQDLPEFIVADDGKPIGTIEDGDAV
                     VFYNFRGDRAIEITRAFVEEHFTEFDRVRHPRVTYAGMLQYDGDLQLPKRFLVAPPAI
                     KDTSSEWFSKSGLAQFACSETQKFGHVTYFWNGNRSNKFDGETWQEVPSDVVPFEQRP
                     WMKAAEITDAMIAALQSGQYKVLRCNYANGDMVGHTGNFRAATMAIEAVDLALARLLP
                     AIDAAGGVALITADHGNADEMYELDKKTRQPALNKDGSYKAKTAHTLNPVPLILYDKV
                     SGGRLGLKPLEAAGLSNIAATVANLLGLHKHDKWDDSLLSVK"
     gene            complement(9590..9934)
                     /locus_tag="P5537_13325"
     CDS             complement(9590..9934)
                     /locus_tag="P5537_13325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004312780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79065.1"
                     /translation="MAGFENYQETTRRIEDEIEHMGVALDVDWSDEAQVRALAREALD
                     HSQDRIREAAASPDDHRLGAKVTLFGLASLMLRTMEESAGVGIESHGGPVWKAFGRAL
                     WLEAQQRREGKA"
     gene            complement(10004..11020)
                     /locus_tag="P5537_13330"
     CDS             complement(10004..11020)
                     /locus_tag="P5537_13330"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HRV79066.1"
                     /translation="MSSTLTDLLSTALAARAPLIARLAAEDTDAWRLFHGTVEGAPGI
                     TVDRYGAVLLAQTFHRPLTVEQLAELEAFYAQALPGLPLVWNDRSGKNSRIANTLPPE
                     QQALAEQPSEFSELGVRYRFQARHAGQDPWLFLDLRAARRRVMQEAEGKSLLNVFAYT
                     CGVGIAAAKAGARHVVNVDFAESALAVGKENARLNELPIRVRFVKSDAFAALRQYAGI
                     GQPKMVRGKHLPPFPELAPHRFDLVFLDPPRYAKSPFGVVDLVHDYAALFKPALLATA
                     EGGTLICCNNVARVEREDWLDQLERSARKAGREVREAEWITPEADFPSRDDNPPLKVV
                     LLRV"
     gene            complement(11088..>11474)
                     /locus_tag="P5537_13335"
     CDS             complement(11088..>11474)
                     /locus_tag="P5537_13335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011286798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HRV79067.1"
                     /translation="AVWNRQLQRVLGTAIGMLFAWWLLSLPLDAWRIALLVILLVFVI
                     ESLVVRHYGLAVIFITPLTILLAEAATLGAAPLAELIESRFIDTVLGCIVGLVGGICL
                     HSARFRAVVGRPLRRLVPSRHLPRDA"
BASE COUNT         1513 a         3813 c         4300 g         1648 t
ORIGIN      
        1 ataatccggc catgacccgc gaaaccgcct cccccgtcgc gctctccacc ctgcgcggcc
       61 tgctcccctt cctgcgcccc taccgcgcac gcgtggtgct cgccttcgtg ctgctgtgcc
      121 tgggctcggc ggcgatcctg gtggtgccgc tggccttccg cgacctgatc gacgcgggct
      181 tcggcggagt ctccgcgggc ggcgccgcag cgcaaggagg tgccgggctg ttcggcgcgc
      241 agggcctgga tggtcgcttc gtcgcgctgt tcgcactcgc ggtgttctgg gcggcggcag
      301 tggcggcgcg ctactacacc gtgtcgtgga tcggcgagcg cgtcaccgcc gacctgcgca
      361 gcgccgtgta tgcgcgcgtg ctgcgccagt cgccgcagtt cttcgagacc ctgcagaccg
      421 gcgaggtgct gtcgcggctc accggcgaca ccacgctggt gcagacggtc gtcggcagct
      481 cgatctccct ggggctgcgc agcctgttcc agttcgtcgg cggcatggtg atgctggcgg
      541 tgaccagcgt gcagctcttc ggcctcatct tcgggctgat ggcgctgctc gcgctgccga
      601 tcacgctgat cggccggcgc gtgcgcagcc tctcgcgcga ggcgcaggac cgcatcgccg
      661 acgcctcggc gctcgctggc gagatcctca atgcgatgcc gacggtgcag gccttcggcc
      721 aggaggccaa cgaggccgcg cgcttcgccg cgcgcgccga gaccggcttc gccaccgcgg
      781 tgcggcgcac gcgggtgcgc gcggcgctca ccgggctgat catcgccgcg gtgatgggca
      841 cgatcatctt cgtgttgtgg atcggcgcgc gccaggtgca ggcgggcgcg ctgtcggtgg
      901 gcgagctcgg cgccttcgtg atctacgccg cgctggtggc gggcggcgcc ggcacgctgg
      961 ccgaggtgtg gggcgacgtg atgcgcgccg cgggggcgac cggacggctg ctggagctgc
     1021 tgcgggcgga gccggcgatc cgggacgcgg gggtggtgga gcgcatgcgg gaggacggag
     1081 gtggaggtgg agattcgcgg ctgccgccgc tcctacagga aaactcgcgt cgcacccccc
     1141 ctgtaggagc ggcggcagcc gcgaacccca ccaccgcccc cgcgatcgag cttggccacg
     1201 tcgtcttccg ctaccctgct cgccccgccg tgccggcgct cgacggcatc gacctgcgca
     1261 tcgcggcggg cgagaggctc gcgctggtcg gcccttccgg tgccggcaag accagcctgt
     1321 tccagctcct gctgcgcttc tacgaggccg gcgagggtca catccgcatc gacggccacg
     1381 acatccgcgc cctgccgctg cgcagcctgc gcgcgcgcat cgccctcgtt ccccaggacc
     1441 cggtgatctt ctccgccagc gcgctcgaca acatccgcta tggccgcccc gacgccggcg
     1501 acgacgaggt gatcgccgcc gcgcgcgccg cggccgccga cgagttcatc gcccgcctgc
     1561 ccgagggcta cgcgaccttc ctcggcgagc gtggcacgcg gctctcgggc ggccagcgcc
     1621 agcgcatcgc gatcgcgcgc gcgatcctga agggcgcgcc catcctgctg ctagacgagg
     1681 ccaccagcgc gctcgacgcc gaatccgagg tcctcgtgca gcaaggcctg gccgcggcaa
     1741 tgcagggtcg caccacgctg atcatcgccc accgcctcgc caccgtgcag aaggtggacc
     1801 gcatcgtggt gatggacgcc ggccgcatcg tcgagaccgg caccccggcc gacctgcgcc
     1861 gccagggcgg actgtatgcg cgcctggcgg cgctgcagct cgagggctga gcgcggttgg
     1921 ggctgccgcc cgagtccatt cgcgcctcgc gccgcccctg atgaaccacc gcgcccggat
     1981 gccatgtagg agcggcggca gccgcgaata cggcgcatgg agttcgcgcc gcggctactt
     2041 caaggccgcc ttcgcgcctg ccggcgctcc tacagaaacc gacgtggtcc gggcccatga
     2101 gcggcggtag ccgcgaataa ggccggccgg cgaccgatgg cggcacgggg aagaaacgcc
     2161 gcgctcgcgt ctcagggcag cgtgcgctcg cgcaggtagc gcggaaagcg cggcaggccg
     2221 gcgggggtga gctcgcggta gcggtaggtg acgagcgcgc cgagcgcggg tgggttggcg
     2281 cgtagcgcgt cgctgaggcc gctgccgatg cgaaagcggc ggccgtcggc ggtctcgacc
     2341 tgtaacgccc ccaccctgcc ctgcagccgg cccttgccgg gcaggtagcc caccacgcgc
     2401 gcctcggcgt ccagccaggg ggtgagcttg cgcagggcct cgctgcggcc gggctgccag
     2461 tgggcgtcgg cgcgatgcag catgaggccc tcgccgcctc ctgcgaggac ctcgtcgagc
     2521 aggcgctgca gcgtggcgcg gtcggccacg cgccgctgcg ggaccgcctg cacccacggc
     2581 gcgccggccg tgtcggccag gctgcgcagg cgtgccagcc gggtgtcgaa gtcgcctggg
     2641 gcgccgggca gttcgaagag catgtagcgc acctcgcgcc acagcggatc ctcgggatcc
     2701 tcgcggcgca gcagcccgga gagcgcgtcg aagcggcggc ggccgagcca gagctcgccg
     2761 tcgagcgcga ccggtggcag cgcggcgagg aaccaggccg gcgccggcag tgtgcgcccg
     2821 ctgcgaaagc gcagcacgct gccgtcccac gaggcgcgca cgccgtcgag cttctcgctc
     2881 acccaccagc ccgcggggtc gatggagggg tcgnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2941 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3001 nnnnnnnnnn nnnctgcggg aactgcaggt gcgtcgatgg gcgcggcggt ctgtgcgaac
     3061 gcgccggccg gaagcagggc gagggccagg atcaggctgc ggatgggcgt cgccgtcccg
     3121 cgcagggccg gtgcgggaat gcgggtggac ggtctcacga gcgaacctcc tgtccgggca
     3181 cgggcggcgg cgcccctgcc tcgccgacgc agtcagggct ggcggccgag ccccgcacgg
     3241 gagaggagcg gcctgcgccc gcgctggcct cctcgagtac ctcgaaggca taggcctgaa
     3301 aatgacaata ggattgtagc ggcgttgccc atgcgctgcc aggccgaatt tcaggcgtcg
     3361 gcggcggcgc gcgcaggcat gcgcttcggg cggaactggc gggtgtcgcg gtagtactcg
     3421 gcggattcgc tgtccgtggt cacgccgggg atgccgagca gcggcagggg tgcgaggctg
     3481 cgcgggctga ggtcgccgat cgtggcggcg aggtgggcgg cgagccaggc gtcggtctcg
     3541 gcgagcgccg ccgctgcggg cagcgcgagc caggcgggat cgaccacgcg gtggagggcc
     3601 ttggcgcaca ggccggggaa gggtgtgcgc aattggtccc agctgccgtg gccgaagacg
     3661 aggaagcggg tgctgcgctg cagggcctcg cgccgcctcc agaacacctc ttcccactcg
     3721 tgcgcggcga gcagcgcggg gagctccgga tcggcggaca cgacgacgat gccgcactcg
     3781 tcgaactggg tcagcgcgtc gcgtcgcggt ccgcgcccgg cgaggccggc ggcggcgcgg
     3841 gcgcgcagct cgtccaggtg caggcggttg cagcaggcct tggtgcgcgg ccaggcgcac
     3901 caggcgagtg cgttgaagaa gtcgtgccag tcggcctcgc gagtggggac ctcgccggtg
     3961 gtgaagatgc gcgcctcata gccggcctcg tcctcgcccg gcgcggcgaa gcggatccgc
     4021 gccccgccgc cgctgtgcgc cgccggcgcg gtctcggcga gcaggacgtc gagcgccgca
     4081 cgcgagggga cgccgggtgc gttgaagcgg gccagccagg gcgcgatcgg ctcgaacagc
     4141 cggcgctcgg cgaaggcggc ggggatggcg agggcgtcgg tcatctgcag aattgtgccc
     4201 tctcgcgggc ggacggacca cagcgggtgt ggcggagggg ccgcggcgcc tggcttgcgg
     4261 ttgcgacagc gcgcccccgc gcccccgcgc catcgtctgc ccccggtcag cgcatctcga
     4321 acagctcctg gtgaaagcgc tcggcgggca ggccgcgggc ggcgagggtg tcgcgcagcg
     4381 tcgcgccgaa gccggccggg ccgcagaacc acacgccggc cagcttccag tcgggcacct
     4441 tgcggcagat gccgtcggcg tcgaggcggc cgtcgcgctg cgagaccagc acgtgcagct
     4501 tcacccgcgc ttgggcggcg agctcgcgca ggcgggcgat gaagccctcg tcgggcgcgc
     4561 tggtgctgta gaacaggtcg accggggcgg cggcgcccgc gcccgcgccc gcgtgcgctt
     4621 cgtcctgcgt gcgcgcctgc atgcgggcga cgaagggggt gatgccgatg ccgcccgcga
     4681 cccagatctg ccgcgcctgg gcgccgctga agtcgaagcg gccgtacggg ccctcgacgc
     4741 gcaccggatc gccggccttc agcgtcgccg gcaggcggcg ggtgtagtcg ccgagcggct
     4801 tgatcatgaa gtccatgcga ccgtcgccgc cccaggcgga cgagatcgtg aaggggtgcg
     4861 ggccctcgcg ctcgtcgaag gtgacgaagg cgaactgtcc ggcctggtgg cccggccacg
     4921 gcgtgtcgag gcgcaggccg acctcgagca cctggttgtc gcgatgctgc accacgcgct
     4981 cgatgtggcc gtgggcgcgg cgtccgctgc cgatgcggcc ggcgagcgag cgcagcgcgg
     5041 cccagctgcc ggcggccatc agcacggcca tgacgatgcc ggccggttcc gtccagtagg
     5101 cgaagggcag cagcaccacg ccgtgcacga ccagcgcgag gtacaccgcc gccatcacgc
     5161 ggtgggtctg cacgaagcgg cggtagggga agcgcttgat cagcgcgatc gcggcgagca
     5221 ccgcgaagag gtagaaggcc cactcgccga tgctctcggc gaggccgcgc tgctcctgga
     5281 agaagcggaa cagctcgacg gtctgctcgg gacgcgggcc gcgcgcgggc ttttccagcc
     5341 agccccagcc gaccgcccac ttggtgccct tggcccacag ccagtgcacc acgcctaccg
     5401 acagaccggc gatgcccagc cacttgtgca gccggtaggc cttgtccatg ccgccgagca
     5461 gcggctcgag cgcggccggg cgcagggcga ggatcatcgc cacgctcatc gttcccatgg
     5521 cgagcacgcc ggtgtaattg accgcgagcg tgcgcagcgc gaagtaggtg tcgccctgga
     5581 tcagcagagg atcggcccac caccacagca ggctgagcgc agcgaggacg aggagaagtg
     5641 caaatttgat gtttttcatg atggctccct tcgagtggga tgcggacgcc atgaggcagc
     5701 ggatcccatg cgggaattgt gcgccacagc atgtgtccgg cttgtagcgt cttgtacccc
     5761 ggggcaggcg cccgcggctg gtcagcgtgg cggcgcgcct atagactcgc gggcgaacct
     5821 cgaccggccg ccgtttgcgg ccaccgcacg gcaccccgaa catgttccag cactccgccc
     5881 cttcccccgc ctggctccag cacgacatgg agcgggtcga tgcgatcatc cgcgcgcaca
     5941 tgaacaacga cgtggcgctg atccgccagg tggtcgagtt catcctgcac ggtgccgagc
     6001 gccagcgccc ggcgctggtg ctggcgaccg cgcgcgcgct cggccacggc ggcgagcggc
     6061 cgcacgcgct ggccgcggcg gtcgagctga tccacatctc gctcgcgctg cacgacgacg
     6121 tgaccgaggc gagcggcggc gcggccgacg gcgcgcacga ggccgcgctg ttcggcaacg
     6181 cgggcaacat cctgctcggc gatctgctct acaccagcgc cttccgcatg atcgtggacc
     6241 tcgacgacat ggaggtgatg cgggtgctgt ccgatgcgac caacgtgatc gccgagggcg
     6301 aggtggcgta tcgcgagctg ctcgccgcgc cggcgtcgcg tacgccggag gcctggctcg
     6361 acatcgcgcg ccgacgccgg gcgaagctct tcgaggcggg cgccgagtgc atggcgatcg
     6421 tgcacggcgc cgacccggcc acgcgctcgg cgctggcgcg cgtcggcctg catgtgggca
     6481 gcgcgcacgc gctgcgcagc gaggcggagg acgcggcgcg cttcggcatc gccgatgcgc
     6541 cggcgcgcgc gcaggcggag atcgaggcgg cgcaggcggt cgtcgatggc ttggcgctgg
     6601 cggacgccgc cgcgcttgtg gcggtggtcg agggctgagc gcgggctcga tcaccggcgg
     6661 gtgctgggct cgagtcgatt gtgcaatcgc cgtgttcgca gctgccgcag ctcctacagg
     6721 ggagcgggaa gcgcgggggt cttgtaggag cgccggcagg cgcgaaagcg gcggtggaat
     6781 tctgagcacg cgtcgattgt ggggcgctgg gttcgcagct gccgcagctc ctacagggga
     6841 gcgggaagcg cgggggtctt gtaggnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6961 nnnnntgagc acgcgtcgat tgtggggcgc tgggttcgca gctgccgcag ctcctacagg
     7021 agatgggacg cgcgggggtc ttgtaggagc gccggcaggc gcgaaagcgg cgggggatgc
     7081 tgggcgtgcg tcgattgtgc aatcgccgtg ttcgcagctg ccgcagctcc tacaggagat
     7141 gggacgcgcg gaggtcttgt aggagcgccg gcaggcgcga aagcagcgct cggggtgccg
     7201 aagacgcccg tcctcacgcc cgcatcaggc cgcccggcac tcgttggcga gtggcttgtg
     7261 ggtgcggccg tcgagcagca ggcctttcca cggcaggtcg atccacacca ggccgctggc
     7321 gctgtcctcg aagcgcggca gacccgagtc ggacgggtcg cgcacgagca ggtactggcc
     7381 gcccttccag ccgagctgga tgcggttgtt caccgtgttg gcgagttcgc ggcggatctg
     7441 caggcgttcg ccgcgctcgc agcggtattc gccgctgggc agggcgaact cgaactggcc
     7501 ggtctgctgg gtgacgcccc gggcggtctc caccttcggt ggctggatcg aacaggcgga
     7561 aagggcgagg gcggcggcga gggtggccgg gagcttgggt gtcatcggtg gtgtccgtct
     7621 gcaaggggtc gagtggattg cggagccttc cgcggacgca gcggcgcggg ggcgccgggc
     7681 atcccgcgcc gggcggtggg gcattcggcc acgtgcggcg agccggttgt gcggaagccg
     7741 gctcgccgcg gcggatcact tcacgctcag caggctgtcg tcccacttgt cgtgcttgtg
     7801 caggccgagc aggttggcga cggtggcggc gatgttcgac aggccggcgg cctcgagcgg
     7861 cttgaggccc agccgaccgc cgctgacctt gtcgtagagg atcagcggca ccgggttgag
     7921 cgtgtgcgcg gtcttggcct tgtagctgcc atccttgttg agtgccggct gcctggtctt
     7981 cttgtcgagc tcgtacatct cgtcggcgtt gccgtggtcg gcggtgatca gcgccacgcc
     8041 gccggcggcg tcgatcgccg gcaagaggcg cgccagcgcc aggtccacgg cctcgatcgc
     8101 catggtcgcg gcgcggaagt tgccggtgtg gccgaccatg tcgccgttgg cgtagttgca
     8161 gcgcagcacc ttgtactggc ccgactgcag cgcggcgatc atcgcgtcgg tgatctcggc
     8221 ggccttcatc cacgggcgct gctcgaaggg cacgacgtcg ctcgggacct cctgccaggt
     8281 ctcgccatcg aacttgttcg agcggttgcc gttccagaag taggtgacgt ggccgaactt
     8341 ctgcgtctcg gagcaggcga actgggccag gccggacttg ctgaaccact cgctcgaggt
     8401 gtccttgatc gccggcgggg cgaccaggaa gcgcttgggc agctgcaggt cgccgtcgta
     8461 ctgcagcatg ccggcgtagg tcacgcgcgg atggcgcacg cggtcgaact cggtgaagtg
     8521 ctcttcgacg aaggcgcggg tgatctcgat cgcgcggtcg ccacggaagt tgtagaacac
     8581 gaccgcatcg ccgtcctcga tggtgccgat cggcttgcca tcgtcggcaa cgatgaattc
     8641 gggcaggtcc tggtcgatgg tgccggggtg cttctcgcgc aggcggtgca ccgcctcggt
     8701 ggcgttggcg aactgcgggc cttcgccgag cacgtgggtg cgccagccgc gcgccaccat
     8761 cggccagttg gcgtcgtagc ggtccatggt gatggtctga cggccaccgc cggaggcgat
     8821 gcgggcgtcg aagccgtcgc ggctgatgtc ctgcaggaag gcctcgaagg gcaccacgta
     8881 gtcgagcgcg ctggtctcgg ggacgtcgcg gccatccagc agggcatgga tgcgcaccgt
     8941 ggccacgccc tcctccttcg cgcgcacgac catcgccttg aggtgatcga tgtggctgtg
     9001 cacgttgccg tcggagaaca ggccgatgaa gtggaggacg cccgcctttc cgttcgcgcc
     9061 cgccttggcg ccggcgacga tctgctgcca ggcctcgccc tgccagatca cgccttcggc
     9121 gatggcgttg gccaccagtg cggcgccttg cgcgtagacc tggccggcgc cgatggcgtt
     9181 gtggccgacc tcggagttgc ccatgtcgtc gtcggacggc atgcccaccg cggtgccgtg
     9241 ggcgcgcagg cggatgttgg ggcactcggc gaacaggcgg tcgagcgtgg gcttgcgcgc
     9301 cgcgtcgatg gcgctgccga cctcgtgctt cggaatgccg tagccgtcca tcacgatgac
     9361 gacgacaggg cccttgacgc cggcgaaggc ggggaatttc tgcagcatgg tcgcttcctg
     9421 aaggagaaat ccggggccgg cgcggcagac gggctgccga ccggtcaaag cgatattttc
     9481 cttcaaatca gcggcggatt ttcatgcgcg ttgtttatcg gcccaatggc ttgctcccgc
     9541 gcacggcacg gacccgggcc gcgtgcgttc cggctggctg gctcgcggct caggccttgc
     9601 cctcgcggcg ctgctgcgcc tccagccaca gcgcgcggcc aaaggccttc cagaccggtc
     9661 cgccatgact ctcgatgccg acgccggcgc tctcctccat cgtgcgcagc atcaggctgg
     9721 cgagaccgaa gagcgtcacc ttcgcgccca gccgatggtc gtccgggctg gccgcggcct
     9781 cgcggatcct gtcctgcgag tgatccagcg cctcgcgcgc gagcgccctc acctgcgcct
     9841 cgtcggacca gtcgacgtcg agcgcgacgc ccatgtgctc gatctcgtcc tcgatcctgc
     9901 gggtggtttc ctgatagttc tcgaatcctg ccatggcctc tcctcgggcg tttccggtgg
     9961 gtgtgcgccg gcgtgccggc tccgggttgt gcgtgggcgt ggcctacacg cgcagcagca
    10021 ccaccttcag cggcgggttg tcgtcgcggc tggggaagtc cgcttccggg gtgatccact
    10081 ccgcctctcg cacctcgcgg cccgccttgc gcgcgctgcg ctcgagctgg tcgagccagt
    10141 cctcgcgctc cacgcgggcg acgttgttgc agcagatcag ggtgccgcct tccgcggtgg
    10201 cgagcagcgc gggcttgaac agcgcggcgt agtcgtgcac caggtcgacc acgccgaagg
    10261 ggctcttggc gtagcgcggg gggtcgagga agacgaggtc gaagcggtgc ggcgccagct
    10321 cggggaaggg cggcaggtgc ttgccgcgca ccatcttcgg ctggccgatg ccggcgtact
    10381 ggcgcagcgc ggcgaaggcg tcggacttga cgaagcgcac ccggatcggc agctcgttga
    10441 ggcgggcatt ttccttgccg accgcgagcg cggattcggc gaagtcgaca ttgaccacat
    10501 ggcgcgcgcc ggccttggcc gcggcgatgc cgacgccgca ggtgtaggcg aacacgttga
    10561 gcagggactt gccctcggct tcctgcatga cgcggcggcg cgcggcgcgc aggtcgagga
    10621 acagccacgg gtcctggccg gcgtggcggg cctggaagcg gtagcgcacg ccgagctcgg
    10681 aaaactccga tggctgctcg gcgagggcct gctgttcggg cggcagcgtg ttggcgatgc
    10741 gcgagttctt gccgctgcgg tcgttccaca ccagcggcag gccgggcagg gcctgggcgt
    10801 agaaggcctc gagctcggcc agctgctcga ccgtcagcgg gcgatggaag gtctgcgcca
    10861 gcagcacggc gccgtagcgg tcgacggtga tgccgggcgc gccttcgacg gtgccgtgga
    10921 agaggcgcca ggcgtcggtg tcttcggcag ccagccgggc gatcaggggg gcgcgggcgg
    10981 cgagcgcggt ggagagcagg tcggtgaggg tggaggacat ggcgattccg gcgcggggcg
    11041 cgccagtatg cccgaagcgg gcgcgatggc cgcagcttgt ctccgcttca ggcgtcccgg
    11101 ggcaggtgcc gcgaaggcac caggcgtcgc agcgggcgtc cgacgacggc gcggaagcgt
    11161 gcgctgtgca ggcagatccc gccgaccagg ccgacgatgc agccaaggac cgtgtcgatg
    11221 aagcgcgatt cgatcagctc ggccagcggc gccgcgccca gggtggcggc ctcggcgagc
    11281 aggatggtga gcggggtgat gaagatcacg gcgaggccgt agtggcgcac caccaggctc
    11341 tcgatcacga agacgagcag gatgaccagc agcgcgatcc gccacgcatc gagcggcagg
    11401 ctcagcagcc accaagcgaa cagcatgccg atcgcggtgc cgaggacgcg ctggagctgg
    11461 cgattccaca ccgc
//
LOCUS       DAOTIN010000107        11175 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_6936_length_11175_cov_8.324820, whole genome shotgun sequence.
ACCESSION   DAOTIN010000107 DAOTIN010000000
VERSION     DAOTIN010000107.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 11175)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 11175)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11175
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6936_length_11175_cov_8.324820"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            3..1964
                     /locus_tag="P5537_13340"
     CDS             3..1964
                     /locus_tag="P5537_13340"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HRV79068.1"
                     /translation="MSDPAPIFADDGPLAAAIPGFRARPQQIEMARKIAEALRENRVL
                     VAEAGTGTGKTFAYLVPALLAGGKVIISTGTKTLQDQLFNRDLPTVRAALKVPVSIAL
                     LKGRANYVCHYHLERNARDGRFLTAQDAADLRAITRFAKLTQTGDKAECTDVREDSLA
                     WIAATSTRDNCLGQDCPNKEECFVMQARRNAMDADVVVVNHHLFFADVMLRDEGMGEL
                     LPACNAVIFDEAHQLPETASLFFGDSVSTAQVLELARDTRSETVAAARDCVAMIDQTR
                     NLEKAARDLRLVFGAESARMSAAQAAERENFEAMVEGLEKALADFHAVLATQAERSEG
                     LGNCLRRSEEMAERLAGWRKPEDKELIRWVEVFTQSLALNATPLHVSDVFKRQLEGHP
                     RAWVFTSATLAVGKADFGHYCRELGLAWMDPPPLTAVWGSPFDYAEQALLYAPAGMPE
                     PNSPDYTERVARVALPLIRAARGRAFVLCTSLRAMRRIHELILDGLQHSGDELPVLLQ
                     GEGSRTELLERFRRLGNAVLVASQSFWEGVDVPGDALSLVVIDKLPFAPPDDPVLAAR
                     VEHMQKQGLSPFVHHQLPKTVINMKQGAGRLIRSERDRGVLCICDPRMIDKSYGKVVW
                     RSLPPMRRTRAEAEAVAFLASLPLPRQGG"
     gene            2042..2536
                     /gene="mobB"
                     /locus_tag="P5537_13345"
     CDS             2042..2536
                     /gene="mobB"
                     /locus_tag="P5537_13345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HRV79069.1"
                     /translation="MKVFGFAGWSGSGKTTLVEKLIPEFTARGLRVSVIKHAHHGFDL
                     DKPGKDSWRHREAGAMQVLMLSNDRWVLMHELRGAPEPTLDEQLRLLEPCDLVLIEGY
                     KAAAVPKIEIHRPSHGKPPLWPENPHVVAVATNAEIDCPLPRLPLDEPAKVADFILDY
                     LNKR"
     gene            2533..3738
                     /locus_tag="P5537_13350"
     CDS             2533..3738
                     /locus_tag="P5537_13350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030151 - molybdenum ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HRV79070.1"
                     /translation="MNPNMLSFDEAYEKLLGFVRPVREVEEVDTMFAAGRVLAVDQHS
                     TIDQPPMDNSGMDGYALRAVDVPVAGTRLPVSQRIPAGSVGHELAPGTAARIFTGAPL
                     PPGADTVVMQELCEHAGDEVVVNTVPRVGEAVRRMGEDIARGARVLPAGLRLTPQAVA
                     LAASVGLARLPVHRRVKVAVFSTGSELVMPGEPLPPGGIYNSNRYLLRGLLAALGCEV
                     EDFGIVPDRLDATREVLRRAAEGHDLILTSGGVSVGEEDHVKPAVEAEGSLDMWKIAM
                     KPGKPLAYGRVHGAAFIGLPGNPVSSFVTFLLMVRPFLLATQGASAVAPAAMQLRADF
                     DWPRPDRRREFLRARMNAQGGVELFANQGSAALESTVWANGLVDIPAGSAIARGETVR
                     FLPYGDLLH"
     gene            3797..4057
                     /gene="moaD"
                     /locus_tag="P5537_13355"
     CDS             3797..4057
                     /gene="moaD"
                     /locus_tag="P5537_13355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin converting factor subunit 1"
                     /protein_id="HRV79071.1"
                     /translation="MTSKVKILYFASLREAVGCSGEELELPAGVGTVGALRSHLAARG
                     EGWQALAAGRNVRAALNQKMAAADSSLDGGDEVAFFPPVTGG"
     gene            4060..4593
                     /gene="moaE"
                     /locus_tag="P5537_13360"
     CDS             4060..4593
                     /gene="moaE"
                     /locus_tag="P5537_13360"
                     /EC_number="2.8.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin synthase catalytic subunit MoaE"
                     /protein_id="HRV79072.1"
                     /translation="MVQARAQGAVEVSVQHEDFDVGAEIARLGEGRLDVGAVASFVGL
                     VRDANDGSGVRAMTLEHYPGMTERALEGIVEQAKARWSLLAVRVIHRHGRLEPADRIV
                     FVGVASAHRGEAFAACEFIMDYLKTQAPFWKCEETPEGARWVDARESDDSAAARWGTA
                     EVQIGQGEDWDDIELRR"
     assembly_gap    4596..4695
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(4773..5279)
                     /locus_tag="P5537_13365"
     CDS             complement(4773..5279)
                     /locus_tag="P5537_13365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phasin family protein"
                     /protein_id="HRV79073.1"
                     /translation="MASKQEQLNELQKKNLEAAMRLAQMSIENSQRIMEIQVNTAKRL
                     FEEGVHNAKALSAAKDPQGAMEMRASYAQRTTEEMLACARQIAEITASTQAEFGRLVG
                     EQLSSGSTDMFEAMQKMFTGMPIADQNALGAMQTAMDTTRAAFEQMTRASTQAFQAFT
                     QQGGKGRR"
     gene            complement(5497..6045)
                     /locus_tag="P5537_13370"
     CDS             complement(5497..6045)
                     /locus_tag="P5537_13370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HRV79074.1"
                     /translation="MGQTTEKLRRLLRHLWLDADDARRALGKAALDRLEARVRASEAG
                     HSGQICLCVEASLPPSYLWRHLARGESLASVIRDRAITLFGKQRVWDTEDNNGVLVYL
                     LLAEHRIEVVADRALARCLEPAAWQDLVTQLATPCRDARFEDALGGAVERLDPLLRAE
                     FPRHGGADRTGEDGLSDRPVLR"
     gene            complement(6045..6938)
                     /locus_tag="P5537_13375"
     CDS             complement(6045..6938)
                     /locus_tag="P5537_13375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HRV79075.1"
                     /translation="MMRYLWRALLALAALCAAGLALAQPLQPVPALQARVTDLTATLS
                     AAQARALEDRLAAFEAAHGSQIVVLLVRSTAPEDIAAYAFRVADAWKIGRREVGDGVL
                     LLVAKDDRKVRIEVARTLEGAIPDLAAWRIIDGAITPAFRRGDFAGGIDAGVEGLFAL
                     IRGEDLPAPQPAARSADGGGIEDLGALLLVGVPMLGAVLVGMLGRKSGAFATGGVTGL
                     IVHLLTASLFLALVGGVLAVVFVLALGIGGGRGGPPHRGGGPIIRGGGLGGGGLGGGF
                     GGGFRSGGGGSFGGGGASGSW"
     gene            complement(6942..7583)
                     /locus_tag="P5537_13380"
     CDS             complement(6942..7583)
                     /locus_tag="P5537_13380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HRV79076.1"
                     /translation="MDSSPARAPVRHLARRLALPLVLAASLSLSGCGYNDFQRLDEQT
                     RAAWSEVLNQFQRRADLIPNLVETVKGEAAFEQETLSRVIEARARATAIQVTPGMLDD
                     PQAMERFQQAQGQLGSALSRLLAVAENYPNLKANQGFQDLRVQLEGTENRVTVARNRY
                     IESVQQYNVLARSFPSNLTAMVFGYQPKPGFTVADEAAISTPPKVDFGGQGGR"
     gene            7745..8071
                     /locus_tag="P5537_13385"
     CDS             7745..8071
                     /locus_tag="P5537_13385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2249 domain-containing protein"
                     /protein_id="HRV79077.1"
                     /translation="MFDNAVHPFDARGVAKRFRHAAIFGALESLEDGEVMRFVNDHDP
                     LPLLNQIQQRYGSQVGINYVARDPGNIVIDFTIQLGAPAAVGAPAAAVAGGGGCGGGG
                     GHGCCS"
     gene            complement(8068..8277)
                     /locus_tag="P5537_13390"
     CDS             complement(8068..8277)
                     /locus_tag="P5537_13390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004372495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79078.1"
                     /translation="MPMTYEQHLDEVATLLYERYDQSEKAAIKLVMAAQEDGFFSGHD
                     DDPSICTLERAQADARAVFRKYGKA"
     gene            complement(8289..9629)
                     /gene="gorA"
                     /locus_tag="P5537_13395"
     CDS             complement(8289..9629)
                     /gene="gorA"
                     /locus_tag="P5537_13395"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HRV79079.1"
                     /translation="MKEYDLIAIGGGSGGVATARRAAEYGARVLLIEAARLGGTCVNV
                     GCVPKKVMWYASGIAQALRDAPGYGFADVAGHLDWATLKQRRDAYIERLNGIYADMLE
                     KSGVELKRGFARFAGPRVVEVDGERFTAPHIVISTGGRPALPDLPGAELGIDSDGFFA
                     LEAQPRRVAVVGAGYIAVELAGVFRGLGSEVSMLVRGDRLLRPFDAMLRDELAAQMQE
                     DGIALRFGTQARALRRQADGSVLVDCGEAGSLEVDALVWATGRQPNTDRLQLAAAGIE
                     ADARGTISTDAFQNTNVPGIYAIGDITGRAELTPVAIAAGRRLALRLFRGVADSKLDY
                     ENIPTVVFSHPAIGTVGLTEEEARKRFGDVKVYTTRFTAMYNALTEHRPKTAMKLVCA
                     GAEERIVGAHVIGDGADEMLQGFAVAVKMGARKADFDDTVAIHPTSAEEFVTMR"
     gene            complement(9702..10259)
                     /locus_tag="P5537_13400"
     CDS             complement(9702..10259)
                     /locus_tag="P5537_13400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HRV79080.1"
                     /translation="MRFTRLARALAPALLIATLAPNAGATDDAATRLYDHSLRRLHAD
                     ESVRLADRYAGQPVLVVNTASHCGFTRQFRELEAVHQRFKERGLKVAGFPSDDFRQEA
                     ADEAETAEVCFQNFGVTFDMYAPIHVTGAEAHPLFREIARQSAAPEWNFHKYVIDRNG
                     RVVAAFGSRTKPDAPEVIAAIEKAL"
     gene            complement(10487..>11175)
                     /gene="ppk2"
                     /locus_tag="P5537_13405"
     CDS             complement(10487..>11175)
                     /gene="ppk2"
                     /locus_tag="P5537_13405"
                     /EC_number="2.7.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008976 - polyphosphate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006793 - phosphorus metabolic process
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="polyphosphate kinase 2"
                     /protein_id="HRV79081.1"
                     /translation="QRVVILFEGRDAAGKGGTIKRFMEHLNPRGARVVALEKPSELER
                     GQWYFQRYIQHLPTAGEIVLFDRSWYNRAGVERVMGFCTPDEYNEFMRQVPEFERNLV
                     RSGIHLIKFWFSVSREEQRRRFKERESHPLKQWKLSPIDLASLDKWDDYTKAKEAMFF
                     YTDTADAPWTVVKSDCKKRARLNALRYVLHKLPYTNKDVSLIGPLDPLLVGRANVVYE
                     RGEKDDVPLL"
BASE COUNT         1578 a         3836 c         3957 g         1704 t
ORIGIN      
        1 cgatgtccga ccccgccccg atcttcgccg acgacggccc gctggctgcc gcgatccccg
       61 gttttcgcgc ccgtccgcag cagatcgaga tggcccggaa gatcgccgag gccttgcgcg
      121 agaaccgtgt gctggtggcc gaggccggca ccggcaccgg caagaccttc gcctacctgg
      181 tgcccgcgct gctggccggc ggcaaggtca tcatctccac cggcaccaag accctgcagg
      241 accagctctt caaccgcgac ctgcccaccg tgcgcgccgc gctcaaggtg ccggtgagca
      301 tcgccctgct caagggccgc gccaactacg tctgccacta ccacctcgag cgcaacgcgc
      361 gcgacggccg cttcctcacc gcgcaggacg ccgccgacct gcgcgcgatc acgcgcttcg
      421 ccaagctcac gcagaccggc gacaaggccg aatgtaccga cgtgcgcgag gactcgctgg
      481 cctggatcgc cgccacctcg acgcgcgaca attgcctcgg ccaggactgc ccgaacaagg
      541 aggagtgctt cgtgatgcag gcgcggcgca acgccatgga cgccgacgtg gtggtggtca
      601 atcaccacct cttctttgcc gacgtgatgc tgcgcgacga gggcatgggt gagctgctgc
      661 cggcctgcaa cgccgtgatc ttcgacgagg cccaccagct gcccgagacc gcgagcctgt
      721 tcttcggcga cagcgtgtcc accgcgcagg tgctggaact cgcgcgcgac acgcgctccg
      781 agaccgtggc cgcggcgcgc gactgcgtgg cgatgatcga ccagacgcgc aatttggaga
      841 aggccgcgcg cgacctgcgc ctggtgttcg gggccgagtc ggcgcgcatg tccgccgcgc
      901 aggccgccga gcgcgagaac ttcgaggcca tggtcgaggg cctggagaag gcgctcgccg
      961 acttccatgc cgtgctcgcc acccaggccg agcgctccga ggggctcggc aactgcctgc
     1021 gccgcagcga ggagatggcc gagcgcctgg cgggctggcg caagcccgag gacaaggagc
     1081 tgatccgctg ggtcgaggtc ttcacccagt cgcttgcgct caacgccacg ccgctgcacg
     1141 tatcggacgt gttcaagcgc cagctcgagg gccacccgcg tgcttgggtt ttcacctcgg
     1201 cgacgctggc ggtgggcaag gccgacttcg gccactactg ccgcgagctc ggcctggcct
     1261 ggatggaccc gccgccgctc accgcggtgt ggggcagccc cttcgactac gccgagcagg
     1321 ccttgctgta tgcgcccgcg ggcatgcccg agcccaactc gcccgactac accgagcgcg
     1381 tcgccagggt ggcgctgccg ctgatccgcg ccgcgcgcgg gcgcgccttc gtgctgtgca
     1441 cctcactgcg tgcgatgcgg cgcatccacg agctcattct cgatgggctg cagcacagcg
     1501 gcgacgagct gcccgtgctg ctgcagggcg aaggctcgcg caccgagctg ctcgagcgct
     1561 tccgccgcct gggcaacgcg gtgctggtgg cgagccagag cttctgggag ggcgtggacg
     1621 tgcccggcga cgcgctgtcg ctggtggtga tcgacaagct ccccttcgcc ccgcccgacg
     1681 acccggtgct ggccgcgcgc gtcgagcaca tgcagaagca gggcctgagc cccttcgtgc
     1741 atcaccagct gcccaagacc gtgatcaaca tgaagcaggg cgccgggcgg ctcatccgca
     1801 gcgagcgcga ccgcggcgtg ctgtgcatct gcgacccgcg catgatcgac aagtcctacg
     1861 gcaaggtcgt ctggcgcagc ctgccgccca tgcgccgcac ccgcgcggag gccgaggcgg
     1921 tggccttcct cgcgagcctg ccgctgccgc gccagggcgg ctgagctggg tcaagggtcg
     1981 cgggcggcgc tctgttgtat ccttccggac tgctcatttc acgccgtggg gcgatgtcta
     2041 gatgaaagtc ttcggtttcg cgggctggtc cggttccggc aagaccaccc tggtcgaaaa
     2101 gctgatcccc gaattcaccg cgcgcggcct gcgcgtatcg gtgatcaagc acgcccacca
     2161 cggcttcgac ctcgacaagc cgggcaagga ctcgtggcgc caccgcgagg ccggcgcgat
     2221 gcaggtgctg atgctgtcga acgaccgctg ggtgctgatg cacgaactgc gtggcgcgcc
     2281 cgagcccacg ctggacgaac agctgcgcct gctcgaaccc tgcgacctgg tgctgatcga
     2341 aggctacaag gccgcagcgg tgcccaagat cgagatccac cgcccctcgc acggcaagcc
     2401 gccgctgtgg ccggagaacc cccacgtcgt cgcggtcgcc accaacgccg agatcgactg
     2461 cccgctgccg cgactgccgc tcgacgagcc ggcgaaggtg gccgacttca tcctggatta
     2521 cctgaacaag cgatgaaccc caacatgctt tccttcgacg aagcctacga gaagctgctc
     2581 ggcttcgtcc gcccggtgcg cgaggtcgag gaggtggaca ccatgttcgc cgccggccgc
     2641 gtgctcgcag tcgatcagca ttccaccatc gaccagccgc cgatggacaa ctccggcatg
     2701 gacggctacg ccctgcgcgc cgtcgatgtg ccggtggccg gaacgcgcct gccggtgtca
     2761 cagcgcatcc ccgcaggcag cgtcggccac gagctcgcgc ccggcaccgc cgcacgcatc
     2821 ttcaccggtg caccgctgcc gccgggtgcc gacaccgtgg tgatgcagga gctgtgcgag
     2881 cacgccggcg acgaggtggt ggtcaacacc gtgccgcgcg tcggcgaggc ggtgcgccgc
     2941 atgggcgagg acatcgcccg cggcgcgcgc gtgctgcccg ccgggctgcg cctcaccccg
     3001 caggcggtgg cgctcgccgc gtcggtgggg ctggcgcggc tgccggtgca tcggcgcgtc
     3061 aaggtcgcgg tgttctccac cggctccgag ctcgtgatgc cgggcgagcc cctgccgccg
     3121 ggcggcatct acaactccaa ccgctacctg ctgcgtggcc tgctcgccgc gctcggctgc
     3181 gaggtcgagg acttcggcat cgtgcccgac cgcctcgacg ccacccgcga ggtgctgcgc
     3241 cgtgcggccg agggccacga cctcatcctc accagcggcg gcgtgtcggt gggcgaggag
     3301 gaccacgtca agccggcggt cgaggccgag ggcagcctgg acatgtggaa gatcgccatg
     3361 aagccgggca agccgctcgc ctacgggcgc gtgcatggcg ccgccttcat cggcctgccg
     3421 ggcaacccgg tgtcgagctt cgtgaccttc ctgctgatgg tgcggccctt cctgctcgcc
     3481 acccaggggg cgagcgcggt ggcgccggct gcgatgcagc tgcgcgccga cttcgactgg
     3541 ccccggcccg accgccgccg cgagttcctg cgcgcgcgca tgaacgcgca gggcggggtg
     3601 gagctcttcg ccaaccaggg ctcggcggcg ctcgagtcga cggtgtgggc caacggcctg
     3661 gtcgacatcc cggccggcag cgcgatcgcg cgtggcgaga cggtgcgctt cctgccctac
     3721 ggcgacctgc tgcactgagg tgccgggagc tcgggcaggg atggcggagg cgggtaatca
     3781 aggaaacggg acggacatga cgagcaaggt gaagattctt tatttcgcga gcctgcgcga
     3841 ggcggtgggg tgctccggcg aggagctgga gctgcccgcc ggtgtcggta cggtcggggc
     3901 gttgcgcagc cacctggccg cgcgcggcga gggctggcag gcgctcgcgg ccgggcgcaa
     3961 cgtgcgcgcg gcgctcaacc agaagatggc ggcagccgac tcgtcgctcg acggcggcga
     4021 cgaggttgcc ttctttccgc cggtgaccgg aggctgatca tggtgcaagc gagagcgcag
     4081 ggcgccgtcg aggtcagcgt ccagcacgag gatttcgacg tcggggccga gatcgcccgc
     4141 ctcggcgagg gacggctcga cgtcggcgcg gtggcgagct tcgtcggcct cgtccgcgac
     4201 gccaacgacg gcagcggcgt gcgcgcgatg acgctcgagc actacccggg catgaccgag
     4261 cgcgccctgg aaggcatcgt cgagcaggca aaggcgcgct ggtcgctgct cgcggtgcgc
     4321 gtcatccacc gccacggccg cctcgagccc gccgaccgca tcgtcttcgt cggcgtggcg
     4381 agcgcacatc gtggcgaagc cttcgccgcc tgcgagttca tcatggacta cctgaagacg
     4441 caggcgccgt tctggaagtg cgaggaaacg cccgagggcg cgcgctgggt cgatgcgcgc
     4501 gagagcgacg actcggcggc agcacgctgg gggaccgcgg aggtgcagat tggccagggc
     4561 gaggactggg acgacatcga gctgcggcgc tgacgnnnnn nnnnnnnnnn nnnnnnnnnn
     4621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4681 nnnnnnnnnn nnnnncggat caagcaaaac ggcgccttgc ggcgccgttt tcagtcgtga
     4741 cgggcacgcc cgccacacga ggcggaggct gctcagcgac gacccttgcc accctgctgg
     4801 gtgaaggcct ggaaggcctg ggtggaggca cgcgtcatct gctcgaacgc cgcgcgggtg
     4861 gtgtccatcg cggtctgcat cgcgcccagt gcattctggt cggcgatcgg catgccggtg
     4921 aacatcttct gcatggcttc gaacatgtcg gtgctacccg agctcaactg ctcgcccacc
     4981 agacggccga actcggcctg ggtcgaagcg gtgatctcgg cgatctggcg cgcacacgcg
     5041 agcatctctt cggtggtgcg ctgcgcgtag ctggcgcgca tctccatcgc gccctgcggg
     5101 tccttcgcgg ccgagagagc cttggcgttg tgcacgcctt cctcgaacag acgcttggcc
     5161 gtgttgacct gaatctccat gatgcgttgc gagttctcga tcgacatctg ggccaggcgc
     5221 atcgccgcct cgaggttctt cttctgaagt tcgttcaact gttcctgttt gctggccata
     5281 ggctcctctc cactcgcacg tatcggttgt ctgagatatt ccgggcttgg cgccctcggg
     5341 acggcgtccc ttgttgttct cgggccggcg catcctgacc ggcttcacca tcccgcttcc
     5401 acaatagcac agctcggagg cgcctccgtg gtgcatccgg tacttcgggg gagtgacgcg
     5461 tgcgtatgat gttgcgttgc agcaagctcg gcagcttcag cgcagcaccg ggcggtcgga
     5521 gagtccgtcc tcgcccgtgc gatcggcgcc accgtgccgt ggaaactcgg cgcgcagcag
     5581 cgggtccagc cgctccaccg cgccgccgag cgcgtcctcg aagcgggcat cgcggcaggg
     5641 cgtggcgagc tgcgtgacga ggtcctgcca ggcggccggt tcgaggcagc gcgcgagggc
     5701 gcggtcggcg acgacttcga tgcggtgctc ggcgagcagc aggtagacca gcacgccgtt
     5761 gttgtcctcg gtgtcccaca cgcgctgctt gccgaacagc gtgatcgcgc ggtcgcggat
     5821 cacgctcgcg agcgattcgc cgcgcgcgag gtggcgccac aggtagctcg gaggcaggct
     5881 ggcctcgacg cacaggcaga tctgcccgct gtggccagcc tcgctcgcgc gtacgcgcgc
     5941 ctccaggcgg tcgagcgccg ctttgccgag cgcgcgacgg gcgtcgtcgg cgtcgagcca
     6001 gaggtggcgc aggagccggc gcagcttctc agtcgtctgc cccatcacca actccccgag
     6061 gcgccgccgc ccccgaagct gccgccaccg ccggagcgga agccgccgcc gaatccgcca
     6121 ccgagcccac cgccgcccag gccgccgccg cggatgatcg gcccgccgcc gcgatgcggc
     6181 ggaccgccac gtccgccgcc gatgccgagc gcgagcacga agaccaccgc gagcacgccg
     6241 ccgacgaggg cgaggaagag gctggcggtg agcagatgca cgatcagccc ggtgacgccg
     6301 ccggtggcga aggccccgga cttgcgcccg agcatgccca ccagcaccgc gccgagcatc
     6361 ggcacgccga cgaggagcag ggcgccgaga tcctcgatgc cgccgccgtc tgcgctacgt
     6421 gcggcgggtt gcggcgcggg caggtcctcg ccgcggatca gcgcgaacag gccttcgacg
     6481 ccggcgtcga tgccgccggc gaagtcgccg cggcggaacg cgggggtgat cgcgccgtcg
     6541 atgatccgcc acgcggccag atcggggatg gcgccctcga gcgtgcgggc gacctcgatg
     6601 cgcaccttgc ggtcgtcctt cgccacgagc agcagcacgc cgtcgccaac ctcgcggcga
     6661 ccgatcttcc aggcgtcggc gacgcggaag gcgtaggcgg cgatgtcctc gggtgcggtg
     6721 ctgcgcacca gcagcaccac gatctggcta ccgtgcgcgg cctcgaaggc ggcgagcctg
     6781 tcctcgagcg cgcgcgcctg cgctgccgag agcgtggcgg tgaggtcggt cacgcgcgcc
     6841 tgcagcgcgg gcaccggctg cagcggctgc gcgagcgcca gcccggccgc gcacagggcg
     6901 gcgagcgcca gcagcgcacg ccagaggtag cgcatcatcg ctcagcgtcc gccctggcca
     6961 ccgaagtcga ccttcggcgg cgtcgagatc gccgcctcgt cggccacggt gaagccgggc
     7021 ttgggctggt agccgaagac catcgcggtg aggttggagg ggaagctgcg cgccagcacg
     7081 ttgtactgct ggaccgactc gatgtagcgg ttgcgtgcca cggtgacgcg gttttccgtc
     7141 ccttccagct gcacgcgcag gtcctggaag ccctggttgg ccttgagatt gggatagttc
     7201 tcggcgaccg cgagcaggcg cgacagcgcg ctgccgagct ggccctgggc ttgctggaag
     7261 cgctccatgg cctgcgggtc gtcgagcatc ccgggcgtca cctggatcgc ggtggcgcgg
     7321 gcgcgcgcct cgatcacccg gctcagcgtc tcctgctcga acgcggcctc gcccttgacc
     7381 gtctcgacca ggttggggat gaggtcggcg cggcgctgga actggttgag cacctccgac
     7441 caggcggcgc gggtctgctc gtcgaggcgc tggaagtcgt tgtacccgca gcccgacagg
     7501 ctcagcgagg cggcgaggac aagcgggagc gcgaggcggc gggcgagatg acgaacgggc
     7561 gcgcgagcgg ggctggaatc cattttgcgt ctccggaaga tgccggtgga aagatcttca
     7621 ctttagcagc gtgcttaggg tttttgtcct tgctcaagga tttcgcccgc gcgcgggact
     7681 aggattcgcg agctgcgatt ccggccgcag gttcgagacc ggaccctcca atggaagaca
     7741 cgagatgttc gataacgctg ttcacccctt cgatgcgcgc ggcgttgcca agcgcttccg
     7801 ccacgccgcc atcttcggtg cgctcgagtc gctcgaggac ggcgaggtca tgcgcttcgt
     7861 caacgaccat gacccgctgc cgctgctgaa ccagatccag cagcgctacg gcagccaggt
     7921 cggcatcaac tacgtcgccc gcgacccggg caacatcgtc atcgacttca ccatccagct
     7981 cggcgcgccg gctgcggtgg gtgcgcccgc cgccgcggtc gccggtggcg gcggttgcgg
     8041 tggcggtggc ggccacggct gctgctccta agcctttccg tatttgcgga agaccgcgcg
     8101 ggcatcggcc tgcgcgcgtt ccagcgtgca gatcgacgga tcgtcgtcgt gcccgctgaa
     8161 gaacccgtcc tcctgggcgg ccatcaccag cttgatggcc gccttttcgc tttggtcgta
     8221 gcgctcgtag agcagcgtgg cgacttcgtc gaggtgttgc tcgtaagtca tcggcatcgc
     8281 ccgctccttc agcgcatggt gacgaattct tcggcgctgg tcgggtggat cgcgaccgtg
     8341 tcgtcgaagt ccgccttgcg cgcacccatc ttcaccgcca ccgcgaagcc ctgcagcatc
     8401 tcgtcggcgc cgtcgccgat cacgtgcgcg ccgacgatgc gctcttctgc gccggcgcac
     8461 accagcttca tcgcggtctt cgggcggtgc tcggtgagcg cgttgtacat ggcggtaaag
     8521 cgcgtggtgt agaccttgac gtcgccgaag cgcttgcgcg cctcttcctc ggtgaggccg
     8581 acggtgccga tggccgggtg gctgaacacc acggtgggga tgttctcgta gtcgagcttg
     8641 ctgtccgcca cgccgcggaa caggcgcagg gcgaggcggc ggcccgccgc gatcgccacc
     8701 ggggtgagct cggcgcggcc ggtgatgtcg ccgatcgcgt agatgccggg cacgttggtg
     8761 ttctggaatg cgtcggtgga gatggtgccc ctggcgtcgg cctcgatgcc ggcagctgcg
     8821 agctgcaggc ggtcggtgtt gggctggcgg ccggtggccc acaccagcgc gtcgacctcg
     8881 agactgccgg cctcgccgca atcgacgagc acgctgccgt ccgcctggcg ccgcagcgcg
     8941 cgcgcctggg tgccgaagcg cagcgcgatg ccgtcttcct gcatctgcgc ggcgagctcg
     9001 tcgcgcagca tggcgtcgaa ggggcgcagc aggcgatcgc cgcgcaccag catggagacc
     9061 tcgctgccca ggccgcggaa cacgccggcc agctccaccg cgatgtagcc tgcgccgacc
     9121 acggcgacac ggcgcggctg cgcttcgagg gcgaagaagc cgtcggagtc gatgccgagc
     9181 tcggcgccgg ggaggtcggg cagggcgggg cggccgccgg tggagatcac gatgtggggc
     9241 gcggtgaagc gttcgccgtc gacctcgacc acccgtgggc cggcgaagcg cgcgaagccg
     9301 cgcttcaact cgacgccgga cttctccagc atgtcggcgt agatgccgtt gaggcgctcg
     9361 atgtaggcat cgcggcgctg cttgagcgtg gcccagtcga ggtggccggc gacgtcggcg
     9421 aagccgtagc ccggtgcgtc gcgcagcgcc tgggcgatgc ccgaggcgta ccacatcacc
     9481 ttcttcggca cgcagccgac attcacgcag gtaccgccga ggcgcgcggc ctcgatcagc
     9541 agcacgcgcg caccgtactc cgcggcgcgg cgggcggtgg cgacgccacc gctgccgccg
     9601 ccgatggcga tcaggtcgta ttccttcatg ggttctccct tgttgtgggc ggctgcgcgt
     9661 gtggccaccg cctcgttgtc gcccccgacg gggcgcggcg ctcagagcgc cttctcgatc
     9721 gccgcgatga cctcgggggc gtcgggcttg gtgcggctgc cgaaggccgc gaccacgcgg
     9781 ccgttgcggt cgatcacgta cttgtggaag ttccattccg gcgccgccga ctggcgcgcg
     9841 atctcgcgga agagcggatg cgcctctgcg ccggtcacgt ggatcggcgc gtacatgtcg
     9901 aaggtgacgc cgaagttctg gaagcagacc tcggcggtct cggcctcgtc cgcggcttcc
     9961 tggcggaagt cgtccgacgg aaatccggcg accttgagcc cgcgctcctt gaagcgctga
    10021 tgcaccgctt ccagctcgcg gaactgtcgc gtgaagccgc agtggctggc ggtgttgacc
    10081 accagcaccg gctggccggc gtagcggtcg gcgagccgta ccgactcgtc ggcgtgcagg
    10141 cggcgcaggc tgtggtcgta caggcgcgtc gccgcatcgt cggtggcgcc ggcattcggg
    10201 gcgagcgtgg cgatcagcag ggcgggggcg agggcacggg caagacgagt gaagcgcatg
    10261 gtcggtctcc ttgaaggcac ggctagcggt ggaccgggtg gggcgcgatc ggttcgcccc
    10321 gcggcgtccc gcggtagcga gagcgcggcg ctcgacggca ttcgtccggc ggttcgaccc
    10381 cgctgcgcct gtccggcatc cgtccacgct cgtacccgag cgccagcgcg cgggcgggca
    10441 gcggtcgatg gctggcgcgg ccacgcccat ggacgcactc gctcgctcac agcagcggca
    10501 cgtcgtcctt ctcgccgcgc tcgtacacca cgttggcgcg gcccaccagc agggggtcga
    10561 gcgggccgat cagcgagaca tccttgttcg tatagggcag cttgtgcagc acgtagcgca
    10621 gcgcgttgag gcgcgcgcgc ttcttgcagt cggacttgac cacggtccac ggcgcatcgg
    10681 cggtgtcggt gtagaagaac atcgcctcct tggccttggt gtagtcgtcc cacttgtcga
    10741 gcgaggcgag gtcgatcggc gacagtttcc actgcttgag cgggtgcgac tcgcgctcct
    10801 tgaagcggcg gcgctgctcc tcgcggctca ccgagaacca gaacttgatg aggtggatgc
    10861 cgctgcgcac caggttgcgc tcgaactcgg gcacctggcg catgaactcg ttgtactcgt
    10921 ccggcgtgca gaagcccatg acgcgctcga cgccggcgcg gttgtaccag gaacggtcga
    10981 acagcacgat ctcgcccgcg gtaggcaggt gctggatgta gcgctggaag taccactggc
    11041 cgcgctcgag ctcggagggc ttctccagcg ccaccacgcg cgcgccgcgc gggttgaggt
    11101 gctccatgaa gcgcttgatc gtgccgccct tgccggcggc gtcgcggccc tcgaacagga
    11161 tcaccacgcg ctggc
//
LOCUS       DAOTIN010000108        11130 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_6972_length_11130_cov_9.274221, whole genome shotgun sequence.
ACCESSION   DAOTIN010000108 DAOTIN010000000
VERSION     DAOTIN010000108.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 11130)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 11130)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11130
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6972_length_11130_cov_9.274221"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(122..1870)
                     /locus_tag="P5537_13410"
     CDS             complement(122..1870)
                     /locus_tag="P5537_13410"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004379941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HRV79082.1"
                     /translation="MESERASGDAHPARVVALIYLCGVLLFGTLLALEWRLIDRTVAA
                     IARERGAALFSLIETTREWNAMHGGVYVVVDETTRPNPWLKHPARDLQTSDGVRLTMV
                     NPAYMTRQIADLALHADGARLHITSLKPIRPENRADDWEAEALARFEAGEREVLALVE
                     GGEQGRGPVHRYMAPLLVREPCLQCHAEQGYVLGDIRGGISVTMPAEVLIARRDQLRT
                     RAVFAYVLAGLLAAGLVHGLLRANRRHVAQVRRINAEQERLIERRTGELAEANRQLAG
                     EVELHRRSERRLAASESRYRAIFDSAAEGIMLLDADLRIVQVNPAFSEITGYMAEEVV
                     GRTPSMLGSGRHDPAFFGDLLATLLATGRWQGEVWNRRKDGDLYVQWMSAVRIGEVDA
                     PEGFVATMTDITSRKQTEEKLRFRANHDALTGLPNRRLFEDRLQSAIASALRHGERFA
                     LMLVDLDRFKGVNDRFGHLAGDALLVEVGRRLQRCVRASDTVARLGGDEFAVILGEVG
                     GREDAVEVAARICASMAEPFELGEGVAQIGASVGIALGPQDDADAEELQRRADAALYT
                     VKHGGRGGFRFHAEQG"
     gene            complement(1938..3818)
                     /locus_tag="P5537_13415"
     CDS             complement(1938..3818)
                     /locus_tag="P5537_13415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV79083.1"
                     /translation="MPFSWFERRVDPYPEAAPGPAPRGFFAFLWAGTEGMRPFILGMM
                     LLTATIGAFEALLFAMLGRVVDWLAAVEPARLWADEGGTLLLLAAIIVGSIALVAVQT
                     MLKHQSLAGNFPMRLRWRFHRLMLGQSMSFYQDEFAGRVSAKVMQTALAVRDTCLILT
                     DILVFVSIYFFTMTAVVASFDAWLLVPFLGWLALYLAALRWFVPRLSRVSRAQADARA
                     LMTGRITDAYTNIATVKLFSHAGREAGYARGAMQEFLATVHAQMRLVSGIEIVNHTLS
                     MGLILATGGTTLWLWSQGQVGVGAVAAATAMALRLNGMSHWVMWEMASLFENVGTVQD
                     GINTLARPHAVVDRADAQPLMVSRGELRFERLVFAYGATGPQARRVIDDFTLTIRPGE
                     KIGVVGRSGAGKSTLVNLLLRFYDLEQGRILIDGQDIAGVTQDSLRAQIGMVTQDTSL
                     LHRSVRDNILYGRPDATDADMVAAAKRAEAHEFVLGLTDPKGRSGYDAHVGERGVKLS
                     GGQRQRIAIARVMLKDAPILLLDEATSALDSEVEAAIQASLYRLMEGKTVVAIAHRLS
                     TIAAMDRLVVMDKGRIVEEGDHHSLLARGGLYARLWAHQSGGFLGEEAEDGTPLHPAC
                     PA"
     gene            complement(3970..5529)
                     /gene="ahpF"
                     /locus_tag="P5537_13420"
     CDS             complement(3970..5529)
                     /gene="ahpF"
                     /locus_tag="P5537_13420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002930453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_process: GO:0006805 - xenobiotic metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009398 - FMN biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HRV79084.1"
                     /translation="MLDANIKTQLKAYLERVTQPIEIVASLDDGPKSKELLELLHDVA
                     EQSKLITLVERRDDDERKPSFSVGPRGGEARVRFAGLPMGHEFTSLILALLQAGGYPP
                     KVEAEVVEQIKALDVELNFETYISLSCHNCPDVVQALNLMAVLNPKIRHTMIDGALFQ
                     KEVEERQIMAVPTVYLNGEEFDQGRLELGQILAKVDTGAAARDAKKLSEKSAFDVLVV
                     GGGPAGAAAAIYAARKGIRTGVVAERFGGQVMDTMAIENFISVKYTEGPKLVAALEEH
                     VKEYEVDVMNLQRVAGVVPGENLHEVKMENGASLKAKTVIVATGARWREMNVPGEKEF
                     RGKGVAYCPHCDGPLFKGKRVAVIGGGNSGVEAAIDLAGVVAHVTLLEFADDLRADAV
                     LQKKLYSLPNVTVIKSAQTTEVTGADKVNGLVYKDRNTEQVHRVELEGIFVQIGLLPN
                     TDFLKGTVELSRFGEIIVDAKGQTSVPGIFAAGDCTTVPYKQIIIAMGEGSKASLSAF
                     DHLIRSSAPAA"
     gene            complement(5661..6224)
                     /gene="ahpC"
                     /locus_tag="P5537_13425"
     CDS             complement(5661..6224)
                     /gene="ahpC"
                     /locus_tag="P5537_13425"
                     /EC_number="1.11.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003858764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0102039 - NADH-dependent peroxiredoxin
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HRV79085.1"
                     /translation="MSLINTQVQPFKAQAFLNGKFVEVSDESMKGKWSVVIFMPAAFT
                     FNCPTEIEDAAEHYAEFQKAGAEVYIVTTDTHFSHKVWHETSPAVGKAKFPLVGDPTH
                     QLTRAFGVHIEEAGLALRGTFVIDPDGVIKTMEVHDNAIARDVTETVRKLKAAQYVAS
                     HPNEVCPAKWKEGEATLAPSIDLVGKI"
     gene            complement(6458..7354)
                     /gene="ftsX"
                     /locus_tag="P5537_13430"
     CDS             complement(6458..7354)
                     /gene="ftsX"
                     /locus_tag="P5537_13430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HRV79086.1"
                     /translation="MSNWFYLHLRALAHALRRLVAQPLGTLLSALVVGIALSLPGGGY
                     LLLDNVGSLARGVSGTPEISLFLAMDAGAAEIAAIEQRLKGENELASYRFVPRDEGLR
                     QLEAAGLGDVLGGLKANPLPDAFVLALRREDPALFERMAERMRTWPKVAHVQLDSAWV
                     ERLHALLALGRSAVLMLAGLLGFALVVVTFNTIRLQILTQHQEIAVSRLLGATDPFIR
                     RPFYWFGSLQGALGGLVALGTMALGVEALAAPVARLAETYGAVFALSGPDLEASLAIV
                     AFAAFLGWLGAAISVRRHLAGT"
     gene            complement(7351..8049)
                     /locus_tag="P5537_13435"
     CDS             complement(7351..8049)
                     /locus_tag="P5537_13435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HRV79087.1"
                     /translation="MIVFEDVAKRYAGGYTALAGVSFEIRHGELVVLSGHSGAGKSTL
                     FKLIPVIERPTAGRVLINGQDVSHLPRTAIPYLRRNLGLVLQESRLLFDRNVYDNVML
                     PLVITGHPAADAAKRVAAALERVGLDGRGKEMPAGLSGGEQQRVAIARAIVNRPSILI
                     ADEPTAHLDPAYAADIAALFRSFNQAGVTVLVSTHDASLFAASRPRRLVLAKGLLVED
                     SRPGGRPAHEEAAA"
     gene            complement(8046..9503)
                     /gene="ftsY"
                     /locus_tag="P5537_13440"
     CDS             complement(8046..9503)
                     /gene="ftsY"
                     /locus_tag="P5537_13440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HRV79088.1"
                     /translation="MFGFLKKKFGKSADEARPVEQAAEEQAAAEVPAEDLAGAHAPVE
                     PQVEMPAVEEARVDTATAEASVAGEVLPAAHEPGTRAEAAAPPESAAEPVADEATSAG
                     APAQASESLREAEPEPESELAAEAASAGAAGGQSEAEPLAEVEAEAEPETEAEPEPAV
                     QQPAAAAVAKKSWTERLKAGLARTRNQIGGGLASLFGLRKIDEDLLEELESTLLMADC
                     GVDATQHLIDDLRQRWKRDRLETADQLQKALADGLHEIIAPLEEPLDVAGHRPFIIMI
                     AGVNGSGKTTSIGKLAKYFQAHGKSVLLAAGDTFRAAAREQLMTWGERNNVTVVAQDS
                     GDAAAVIFDAINAARARKIDVVLADTAGRLPTQLHLMEEIAKVRRVIAKADPSGPHEV
                     LLVLDANIGQNALAQVKAFDKAIGVTGLVVTKLDGTAKGGVLAAIARQCPKPLRFIGV
                     GEGIDDLQPFKAREFVDALFEPGAGAVKAGAEARR"
     gene            9653..11068
                     /locus_tag="P5537_13445"
     CDS             9653..11068
                     /locus_tag="P5537_13445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004379889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pitrilysin family protein"
                     /protein_id="HRV79089.1"
                     /translation="MQDKSMFRHTLASLPGSRLARSLLLGAALSAALAAPALANPFET
                     TLANGMKLIVKEDRRAPSVVHMVWYRAGAMDEPDGVSGVAHVLEHMMFKGTKEVGPGE
                     FNRRVAAVGGRDNAFTGKDYTAYFQQVPPAQLPAMMALEADRMKNLVLTDEEFAREIE
                     VVKEERRLRTDDQPRALVFEQLMATAYQAHPYRRPVIGWMPDLEAMQPEDARAWYRRW
                     YAPNNAYLVVVGDVDHREVFRDAERTYGTIPAAELPARRISPEPAQRGPRTAVVKAPA
                     ELPYIAMSWHAPALRDPAGDREAYALDVLAAVLDGYDGARLTRSLVRDQRIAVSVGAG
                     YDTGNRGPALFHLHGVPAAGTSPEALAEALRAEVRRIADEGISAAELARVKTQAIATQ
                     VYKRDSLMGQAMEIGYLESAGLSWRDEQRLLEGLRAVTAEEVQAVAKRHFDDTSLNTA
                     RLDPQPLAEKRPRSPFAAPRH"
BASE COUNT         1657 a         3897 c         3885 g         1691 t
ORIGIN      
        1 cgatccctgc acggccccgt tcgcggctgc cgccgctcct acaagggctt gcacaggcgc
       61 ggttttgtgt aggcgcgccg gcaggcgcga attcggcggg cagggccgcc gcgcgtgcgg
      121 atcagccctg ctcggcgtgg aagcggaagc cgccgcggcc gccgtgcttg acggtgtaga
      181 gcgcggcgtc tgcgcggcgc tgcagttcct cggcatcggc gtcgtcctgc gggccgaggg
      241 cgatgccgac cgaggcgccg atctgcgcca cgccctcgcc gagctcgaag ggctcggcca
      301 tggacgcgca gatgcgcgcc gccacctcca cggcatcctc gcgaccgccg acctcgccga
      361 ggatcaccgc gaactcgtcg ccaccgagac gcgccaccgt gtcggaggcg cgcacgcagc
      421 gctgcagcct gcgcccgacc tcgaccagca gcgcatcgcc cgcgaggtgg ccgaagcggt
      481 cattgacgcc cttgaaacgg tcgaggtcga ccagcatcaa tgcgaagcgc tcgccatggc
      541 gcagcgcgct ggcgatcgcg gactgcaggc ggtcctcgaa caggcgacgg ttgggcaggc
      601 cggtgagggc gtcgtggttg gcacggaagc gcagcttctc ctcggtctgc ttgcgcgagg
      661 tgatgtcggt catcgtggcg acgaagcctt cgggcgcgtc cacctcgccg atccgcaccg
      721 cagacatcca ctgcacgtag agatcgccgt ccttgcgccg gttccacacc tcgccctgcc
      781 agcgcccggt agcgagcagc gtggcgagga gatcgccgaa gaaggccgga tcgtggcgcc
      841 ccgagccgag catggatggc gtgcggccga ccacttcttc cgccatgtag ccggtgatct
      901 cgctgaaggc gggattgacc tggacgatgc gcaagtccgc gtccagcagc atgatgccct
      961 cggccgcgct gtcgaagatc gcgcggtagc gcgactcgct cgctgccagc ctgcgctcgc
     1021 tgcgccgatg cagctcgacc tcgccggcga gctggcgatt ggcctcggcg agttcgccgg
     1081 tgcgccgttc gatcaggcgc tcctgctcgg cgttgatgcg ccgtacctgg gcgacgtggc
     1141 gccggttggc gcgcagcagc ccgtgcacca ggccggcggc gagcaggccg gcgagcacgt
     1201 aggcgaagac cgcgcgcgtg cgcaactggt cgcgccgggc gatcagtacc tcggccggca
     1261 tcgtcaccga gatgccgccg cggatgtccc ccaacacgta accctgctcg gcgtggcatt
     1321 gcaggcaggg ctcgcgcacc agcagcggcg ccatgtagcg atgcaccggg cccctgccct
     1381 gctcgccgcc ctccaccagc gccagcacct cgcgctcgcc ggcctcgaaa cgggcgagcg
     1441 cctcggcctc ccagtcgtcg gcgcggttct cggggcggat cggcttcagg ctggtgatgt
     1501 gcaggcgcgc gccgtccgcg tgcagggcga ggtcggcgat ctggcgcgtc atgtaggcgg
     1561 ggttgaccat ggtcagacgc acgccgtcgc tggtctgcag gtcgcgcgcg gggtgcttca
     1621 gccagggatt gggccgggtc gtctcgtcca ccacgacata cacgccgccg tgcatggcgt
     1681 tccactcgcg ggtggtctcg atcagcgaga acagcgcggc accgcgctcg cgcgcgatcg
     1741 ccgcgaccgt gcggtcgatc agccgccact ccagcgcgag cagcgtgccg aacagcagca
     1801 cgccacagag atagatgagc gcgacgacgc gcgcgggatg cgcatcgccg gatgcgcgct
     1861 ccgactccat gtcatcgcct ccggtgagca tgccccattc tatggacaaa gcatgcgcgg
     1921 gagcgtgatc cgtttcctca cgccgggcag gccggatgca gcggcgtgcc gtcctcggct
     1981 tcctcgccga ggaaaccgcc gctctggtgg gcccacaggc gcgcgtacaa gccgccgcgg
     2041 gcgaggaggc tatggtggtc gccctcctcg acgatcctgc ccttgtccat caccaccagg
     2101 cggtccatcg ccgcgatcgt cgacagccgg tgcgcgatcg cgaccacggt cttgccctcc
     2161 atcaggcggt acaggctggc ctggatcgcc gcctcgacct cggagtcgag cgcgctggtg
     2221 gcctcgtcga ggagcaggat gggcgcgtcc ttgagcatca cgcgcgcgat cgcgatacgc
     2281 tggcgctggc cgccggagag cttcacgccg cgctcgccga cgtgggcgtc gtagccgctg
     2341 cgccccttgg ggtcggtcag cccgaggacg aactcgtgcg cctcggccct tttcgcggcg
     2401 gcgaccatgt cggcgtcggt cgcgtcgggg cggccgtaga ggatgttgtc gcgcaccgaa
     2461 cgatgcagca gcgaggtgtc ctgggtgacc atgccgatct gcgcccgcag gctgtcctgc
     2521 gtcacgccgg cgatgtcctg gccatcgatc aggatgcggc cctgctcgag gtcgtagaag
     2581 cgcagcagca ggttcaccag cgtcgacttg cccgcgcccg agcgcccgac cacgccgatc
     2641 ttctcgcccg ggcggatggt cagggtgaag tcgtcgatca cccgtcgcgc ctggggcccg
     2701 gtggcgccgt aagcgaacac gagccgctcg aagcgcagct cgccgcggct caccatcagg
     2761 ggctgcgcgt cggcgcggtc gaccaccgcg tgcgggcgcg ccagggtgtt gatgccgtcc
     2821 tgcacggtgc cgacgttctc gaacagcgag gccatctccc acatcaccca gtgcgacatg
     2881 ccgttgagcc gcaacgccat cgcggtcgcc gccgccaccg cgccgacgcc gacctggccc
     2941 tggctccata gccacagcgt ggtgccgccg gtggcgagga tcagccccat cgacagggtg
     3001 tgattgacga tctcgatgcc gctcaccagg cgcatctgcg catgcacggt ggcgaggaac
     3061 tcctgcatcg caccgcgcgc gtagcccgcc tcgcggccgg cgtgggagaa cagcttgacg
     3121 gtggcgatgt tggtgtaggc atcggtgatg cgcccggtca tcagcgcgcg cgcgtcggcc
     3181 tgggcgcgcg acaccctgga caggcgcggc acgaaccagc gcagcgcggc gaggtagagc
     3241 gccagccagc cgaggaatgg gacgagcagc caggcgtcga agctcgccac caccgcggtc
     3301 atggtgaaga aatagatgct cacgaagacc aggatgtcgg tcaggatcag gcaggtgtcg
     3361 cgcaccgcga gcgcggtctg catgaccttg gccgacaccc ggccggcgaa ttcgtcctgg
     3421 tagaagctca tgctctggcc gagcatcagg cggtggaagc gccagcgcag ccgcatcggg
     3481 aagttgcccg ccaggctctg gtgcttgagc atggtctgca ccgcgaccag cgcgatgctg
     3541 ccgacgatga tggcggcgag cagcagcagg gttccgcctt cgtccgccca caggcgcgcg
     3601 ggttcgaccg cggccagcca gtcgacgaca cggccgagca tggcgaacag cagggcctcg
     3661 aaggcgccga tggtcgcagt gagcagcatc atgccgagga tgaagggccg catgccctcg
     3721 gtacccgccc acaggaaggc gaagaagccg cgcggcgcgg ggccgggggc ggcttcgggg
     3781 taggggtcga cgcggcgttc aaaccagctg aaaggcacca gagatctcca gaggaatgca
     3841 cgagcccatg ggaccgggat cacccgcgaa cattcccggc ggaagtcgcg ctcgcaaagc
     3901 aatgcgcccc gcacgaagcg gggcggggct cgcggctgcc gccacccggc acggggcggc
     3961 gggcaggaat caggcggccg gcgcgctgct gcggatcagg tgatcgaagg ccgacagcga
     4021 ggccttcgag ccttcgccca tggcgatgat gatctgcttg tagggcaccg tggtgcagtc
     4081 gccggcggcg aagatgcccg ggaccgaggt ctgccccttg gcatcgacga tgatctcgcc
     4141 gaagcgcgac agctctaccg tgcccttgag gaaatcggtg ttgggcagca agccgatctg
     4201 tacgaagatg ccctccagtt cgacgcggtg cacctgctcg gtgttgcggt ccttgtacac
     4261 caggccgttg accttgtcgg cgccggtgac ctcggtggtc tgcgcgctct tgatcacggt
     4321 gacgttaggc aggctgtaga gcttcttctg cagcacggcg tcggcgcgca ggtcgtcggc
     4381 gaactcgagc agggtcacat gggcaaccac gccggcgagg tcgatcgcgg cctcgacgcc
     4441 ggagttgccg ccgccgatca ccgccacacg cttgcccttg aacagggggc cgtcgcagtg
     4501 cgggcagtag gccacgccct tgccgcggaa ctccttctcg ccgggcacgt tcatctcgcg
     4561 ccagcgcgca ccggtggcga cgatcacggt cttggccttg aggctggcgc cgttctccat
     4621 cttcacttcg tgcaggtttt cgcccggcac cacgccggcg acgcgctgca ggttcatcac
     4681 gtcgacttcg tattccttga cgtgctcctc aagggctgcg accagcttgg ggccttcggt
     4741 gtatttgacc gagatgaagt tctcgatcgc catcgtgtcc atgacctggc cgccgaagcg
     4801 ctcggccacc acgccggtgc ggataccctt gcgcgcggca tagatcgccg ccgccgcgcc
     4861 ggccgggcca ccgccgacga cgagcacgtc gaacgcagac ttctcggaca gcttcttcgc
     4921 gtcgcgtgcg gcggcgccgg tgtcgacctt ggcgaggatc tggccgagct ctaggcggcc
     4981 ctggtcgaac tcctcgccgt tcaggtacac cgtcggcacc gccatgatct ggcgctcctc
     5041 gacctccttc tggaacagtg cgccgtcgat catggtgtgg cggatcttcg ggttgagcac
     5101 cgccatcagg ttgagcgcct gcaccacgtc cgggcagttg tggcaggaca gcgagatgta
     5161 ggtctcgaag ttgagctcga cgtcgagggc cttgatctgc tcgaccacct cggcctcgac
     5221 cttgggcggg tagccgccgg cctgcagcag ggcgaggatc agcgaagtga actcgtggcc
     5281 catgggcagg ccggcgaagc gcacgcgcgc ctcaccgccg cgcgggccga ccgagaagga
     5341 gggcttgcgt tcgtcgtcgt cgcgacgctc gaccagggtg atcagcttcg actgctcggc
     5401 gacgtcgtgc agcagctcga gcagctcctt cgacttcgga ccatcatcca gcgacgccac
     5461 gatctcgatc ggctgcgtca cccgctccag gtaggctttc agttgagtct tgatgttggc
     5521 gtccagcatg atggtcactc cctttctgtt ttgcgaccgc cgctgtttac ggcagtccgg
     5581 atacgacgca gccggcgcgt ggccggctgc ggaacttgcg ccccggggcc gcggtggccc
     5641 gggggatgtg cagcgctacc ttagatcttg ccgaccaggt cgatcgacgg ggccagcgtg
     5701 gcttcgcctt ccttccactt cgccgggcac acttcgttcg ggtgcgaggc gacgtactgc
     5761 gcggccttga gcttgcgaac ggtctcggtc acgtcacggg cgatggcgtt gtcgtgcact
     5821 tccatcgtct tgatgacgcc gtccggatcg atcacgaagg tgccgcgcag ggccaggccg
     5881 gcttcctcga tgtgcacgcc gaaggcgcgg gtcagctggt gcgtcgggtc gccgacgagc
     5941 gggaacttgg ccttgccgac ggccggcgag gtctcgtgcc acaccttgtg cgagaagtgg
     6001 gtgtcggtgg tgacgatgta cacctcggcg cccgccttct ggaactcggc gtagtgctcg
     6061 gccgcgtcct cgatctcggt cgggcagttg aaggtgaagg cggccggcat gaagatcacc
     6121 acggaccact tgcccttcat gctctcgtcg gagacttcga cgaacttgcc gttgaggaag
     6181 gcttgggctt tgaacggttg aacctgggtg ttgatcagcg acatctgtaa tcctccagaa
     6241 gggttgtttg aacggtgttg cgaaactcga tggaccaaag tttagacccg ttccttgaat
     6301 tgctctaatt gattatcgag atccagacga ttggaagtcc ctatgaactc ccgattggcg
     6361 gaacctgttg ccgatcgcgc agccactgcc ccgacggatg cgggacgatg aaccaccacg
     6421 cgaaggcaca ctataaattg gggcggatga cggaaattca agtcccggcg agatgtcgcc
     6481 gcaccgagat cgccgcgccc agccagccga ggaaggcagc gaaggcgacg atcgccaggc
     6541 tggcctcgag gtcgggcccg ctcagcgcga agaccgcacc gtaggtctcg gctagccgcg
     6601 ccaccggggc ggcgagcgcc tcgaccccga gcgccatggt gccgagcgcg accaggccgc
     6661 cgagcgcgcc ctgcaggctg ccgaaccagt agaaggggcg gcggatgaag gggtcggtgg
     6721 cgccgagcag ccggctcacc gcgatctcct ggtgctgggt gaggatctgc aggcggatgg
     6781 tgttgaaggt gaccaccacc agcgcaaaac cgagcaggcc ggcgagcatc agcaccgccg
     6841 agcgcccgag ggcgagcagc gcgtgcaggc gctcgaccca ggccgagtcg agctgcacgt
     6901 gcgccacctt gggccaggtg cgcatgcgct cggccatgcg ctcgaacaag gccggatcct
     6961 cgcgccgcag cgcgagcacg aaggcgtcgg gcagcgggtt ggccttgagc ccgccgagca
     7021 cgtcgcccag gccggcggcc tcgagctggc gcaggccctc gtcgcgcggc acgaagcggt
     7081 agctggcgag ctcgttctcg cccttcaggc gctgctcgat cgcagcgatc tcggccgcgc
     7141 cggcgtccat ggccaggaac aagctgatct cgggcgtgcc cgagacgccg cgcgcaagcg
     7201 agccgacatt gtcgagcagc aggtagccgc cgcccggcaa cgacagcgcg atgccgacca
     7261 ccagcgccga aagcagggtg ccgagcggct gcgccaccag ccggcgtagc gcgtgggcga
     7321 gcgcgcgcag gtgcaggtag aaccagttgc tcatgccgcg gcctcctcgt gtgccggccg
     7381 tccgcccggg cgcgaatcct ccaccagcag ccccttggcc agcaccagcc ggcgcggacg
     7441 gctggccgcg aacaggctgg cgtcgtgggt ggacacgagc acggtgaccc cggcctggtt
     7501 gaaggagcgg aacagcgccg cgatgtcggc ggcgtaggcg gggtcgaggt gggccgtggg
     7561 ctcgtcggcg atcaggatcg acggccggtt aacgatcgcg cgcgcgatcg ccacgcgctg
     7621 ctgctcgccg cccgacaggc ctgccggcat ctccttgccg cgcccgtcga gaccgacgcg
     7681 ctcgagcgcc gccgccaccc gcttcgcggc atcggcggcg ggatggccgg tgatcaccag
     7741 cggcagcatc acgttgtcgt acacgttgcg gtcgaacagc aggcggctct cctgcagcac
     7801 caggccgagg ttgcggcgca ggtaggggat ggccgtgcgc ggcaggtgcg agacgtcctg
     7861 gccgttgatc agcacgcgcc cggcggtggg gcgctcgatc accgggatga gcttgaacag
     7921 cgtgctcttg cccgcgccgg aatggccgga gagcacgacc agctcgccat ggcggatctc
     7981 gaagctgacc cccgccagcg ccgtgtagcc gcccgcatag cgcttggcca cgtcctcgaa
     8041 gacgatcatc tgcgcgcttc cgcccccgcc ttgaccgcgc cggcgcccgg ttcgaacagc
     8101 gcatcgacga actcgcgcgc cttgaagggc tgcaggtcgt cgatgccctc gccgacgccg
     8161 atgaagcgca gcggcttcgg acactggcgc gcgatcgccg ccagcacgcc gcccttggcg
     8221 gtgccgtcga gcttggtcac caccaggccg gtgacgccga tcgccttgtc gaaggccttc
     8281 acctgcgcga gcgcgttctg gccgatgttg gcgtcgagca ccagcagcac ctcgtgcggc
     8341 ccgctcgggt cggccttggc gatcactcgg cgcaccttgg cgatctcttc catgaggtgg
     8401 agctgggtgg gcaggcggcc ggcggtgtcg gcgagcacga cgtcgatctt gcgcgcccgc
     8461 gcggcgttga tcgcgtcgaa gatcaccgcc gcggcgtcgc cgctgtcctg cgccaccacg
     8521 gtgacgttgt tgcgctcgcc ccaggtcatc agctgctcgc gcgcggcggc gcggaaggtg
     8581 tcgccggcgg cgagcagcac gctcttgccg tgggcctgga agtacttcgc cagcttgccg
     8641 atcgaggtcg tctttccgga gccgttgacg cccgcgatca tgatgatgaa ggggcgatgg
     8701 ccggcgacgt cgagcggctc ctcgagcggg gcgatgatct cgtgcaggcc gtcggcgagc
     8761 gccttctgga gctggtccgc ggtctccagg cggtcgcgct tccagcgctg gcgcaggtcg
     8821 tcgatcaggt gctgggtggc gtcgacaccg cagtcggcca tcagcagggt ggactcgagc
     8881 tcctcgagca gatcctcgtc gatcttgcgc agcccgaaca ggctcgccag cccgccgccg
     8941 atctggttgc gggtgcgcgc gaggccggcc ttgaggcgct cggtccacga cttcttcgcg
     9001 accgcagcgg cggccggctg ctgcaccgcg ggctcgggct ccgcttcggt ttcgggctcc
     9061 gcttcggctt cgacctcggc taggggctct gcttcagatt gccccccggc tgctccggca
     9121 gacgcggcct ccgctgccag ctcggactcc ggctcgggct cggcttcccg cagcgactcg
     9181 gacgcctgcg cgggcgcgcc cgcgctcgtc gcctcgtccg cgacgggctc cgcggccgat
     9241 tccggcggcg ccgcagcctc ggcccgcgtc ccgggttcat gggcggcagg gagcacctcg
     9301 cccgccacgc tcgcctcggc agtcgccgtg tcgacccgcg cctcctcgac cgccggcatc
     9361 tccacctgcg gctcgacggg cgcgtgcgcg ccggcgaggt cttcggccgg gacctcggct
     9421 gcggcctgct cctcggccgc ctgctcgacg ggcctggcct cgtcggcgga cttgccgaac
     9481 ttcttcttca ggaaaccaaa catgaaacgc tcgggtcaga ggggacgttt tgcgtcgacg
     9541 cgcgcggccc ggcaagcatg ggcgcgcacc gccgatcacg ctaagatgcg gctccccggc
     9601 acgggctgcg ccacgcgcag cgggccttgc ggagtgccgc ggattctaac agatgcagga
     9661 caagtccatg tttcgccaca ccctcgccag cctccccgga agtcgcctcg cgcgcagcct
     9721 gctgctcggc gcggcgctct ccgccgcgct cgccgcaccc gccctcgcca accccttcga
     9781 gaccacgctc gccaacggca tgaagctgat cgtcaaggaa gatcgccgcg cgccctcggt
     9841 ggtgcacatg gtgtggtacc gcgccggcgc gatggacgag ccggacggcg tctcgggtgt
     9901 cgcccacgtg ctcgagcaca tgatgttcaa gggtaccaag gaggtcggcc cgggcgagtt
     9961 caacaggcgc gtggccgccg tcggcggacg cgacaacgcc ttcaccggca aggactacac
    10021 cgcctacttc cagcaggtgc cgccggcgca gctgccggcg atgatggcgc tcgaggccga
    10081 ccgcatgaag aacctcgtgc tcaccgacga ggagttcgcg cgcgagatcg aggtggtcaa
    10141 ggaagaacgc cgcctgcgca ccgacgacca gccgcgcgcg ctggtgttcg agcagctgat
    10201 ggccaccgcc taccaggccc acccctatcg ccgcccggtg atcggctgga tgcccgacct
    10261 cgaggccatg cagccggagg atgcgcgcgc gtggtaccgg cgctggtacg cgcccaataa
    10321 cgcctacctg gtggtggtgg gcgatgtgga ccaccgcgag gtgttccgcg acgccgagcg
    10381 gacctacggc accattcccg ccgccgagct gccggcgcgc cgcatctcgc ccgagccggc
    10441 gcagcgcggc ccgcgcaccg cggtggtgaa ggcccccgcc gagctgccct acatcgcgat
    10501 gagctggcac gcgcccgcgt tgcgcgaccc cgcgggcgac cgcgaggcct acgcgctcga
    10561 tgtgctcgcc gcggtgctcg acggctacga cggcgcccgc ctcacccgca gcctggtgcg
    10621 cgaccagcgc atcgcggtca gcgtgggcgc cggctacgac accggcaacc gcggcccagc
    10681 gctgttccac ctgcacggcg tgcccgccgc tggcaccagc ccggaggcgc tcgccgaggc
    10741 cttgcgcgcc gaggtgcgcc gcatcgccga cgaaggcatc agcgccgcgg agctcgcgcg
    10801 cgtcaagacg caggcgatcg ccacgcaggt atacaagcgc gactcgctga tgggccaggc
    10861 gatggagatc ggctatcttg aatccgcagg gctgtcctgg cgcgacgagc aacgactcct
    10921 cgaaggcctg cgcgcggtga ccgcggagga ggtgcaggcg gtggcgaagc gccacttcga
    10981 cgacaccagc ctcaacaccg cccgcctcga tccgcagccg ctcgccgaaa agcgcccgcg
    11041 ctcgcctttc gccgccccgc gccactgatg gcgccgccag gaagccccgc ccccatgacc
    11101 gcctccgccc tgatcgcaaa gccctcccgg
//
LOCUS       DAOTIN010000109        11031 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_7059_length_11031_cov_9.085277, whole genome shotgun sequence.
ACCESSION   DAOTIN010000109 DAOTIN010000000
VERSION     DAOTIN010000109.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 11031)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 11031)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11031
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_7059_length_11031_cov_9.085277"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..914)
                     /locus_tag="P5537_13450"
     CDS             complement(<1..914)
                     /locus_tag="P5537_13450"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HRV79090.1"
                     /translation="MRTLDYTTEDLCRAPRLRIALVTETWAPEVNGVAMTLGRMVDGL
                     IRRGHGVQLIRPRQQPGETALHGGGLEEVLARGLRLPRYDGLKLGLPARVRLLREWSR
                     QRPDLVHVATEGPLGWTAVTAANKLRIPVSSDFHTNFDHYSGHYGMGWLRQPVAAYLR
                     RFHNRSAVTFVPTAALAAQLSAQGYRSVEVISRGVDTALYSPARRDEALRHAWGVPAG
                     GLAVISVGRLAPEKNLALALRAFAAIRRLRPDARMILVGDGPQRAALARAHPDAVFVG
                     MRHGEDLAAHYASADLFLFPSLTETFGNV"
     gene            complement(1004..2692)
                     /locus_tag="P5537_13455"
     CDS             complement(1004..2692)
                     /locus_tag="P5537_13455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HRV79091.1"
                     /translation="MNNKQSEQALEDRILIQSKPGLGKSFVTFATLAALALLAPGVHA
                     MAAGEAAPVAIEPATGDSALALRIEQRLRERAAMADETTALFYLARAYRPVWTEPARA
                     EALLAAVDALRGHGLDPADFAPLRLRAALPAEADPDRAAERELLFTDTLAALLFQLRY
                     GKVDPHALYREWNFTPPPNPYERAGELARVLQAPDLAAAVEAQAPDLPLYRALRAELL
                     AQQGLLAGGDWPRVAAGPTLKPGARSARVPSLRARLAAAGESVLDARDKSHYDEALVE
                     AVERFQAAHGLQADGVLGAQTLEALNASPAQRVAQIRANLERLRWVAGDLQGDRLLVD
                     IVGYHADLVLDGQPVWASRVIVGKPRRRTPSLLDSVTHLVLNPKWVVPPTILREDVIP
                     GAARNPSYLANRRMRVVDRSGQTVDPSTIDWSGARQSGFPYRIEQQSGASGSLGRIKF
                     SLSNPYVIYLHDTNTRSLFKRAERALSSGCVRVEKPEELAVVLLADAERWSAQALQAA
                     LDSGRTRTLDVGRDVKVLLHYATAALDDAGKVLLRNDIYGYDAAIVAALDAPVR"
     gene            2691..3254
                     /locus_tag="P5537_13460"
     CDS             2691..3254
                     /locus_tag="P5537_13460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF882 domain-containing protein"
                     /protein_id="HRV79092.1"
                     /translation="MSKIIPNQVVPHRRLLLKGLATLPMGLSAAAAQAARDPHLAFRH
                     THTEERLRVAFRNRQGYIQPALQRMDWLLRDFRTGESTRMDPRLYDMLHALSLACGGD
                     TFEIISGYRSPTTNTMLRKTRGGGVAKRSLHMDGKAIDIRLVGVDTARLRDAALALGA
                     GGVGYYPDSDFVHIDTGPVRSWGPKSA"
     gene            complement(3286..3651)
                     /locus_tag="P5537_13465"
     CDS             complement(3286..3651)
                     /locus_tag="P5537_13465"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004143 - diacylglycerol kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HRV79093.1"
                     /translation="MESPFKGKTGLRRILNAARYSMDGLRAAYRHEDAFRQEIWLTLV
                     AVPLALWLGEGAIERALMIGSVLLVLVVELLNSAVEATVDRVSLERHELAKRAKDVGS
                     AAVLVALLNAAVVWGLLLR"
     gene            3769..6144
                     /locus_tag="P5537_13470"
     CDS             3769..6144
                     /locus_tag="P5537_13470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004317753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDOD domain-containing protein"
                     /protein_id="HRV79094.1"
                     /translation="MTRTIGRFEIRRELGRGAQSVVHLAWDPQLEREVALKALHLGPR
                     PGHDNASLLAEARAVSRLRHPGIVPVFEAGEDGGDPYLVFEYVPGESLAALLDRRGAL
                     PAGEAVERMLEVLAALAEAHAQGVIHRDLKPSNVLLDAAGHARVMDFGIARRVEAAGA
                     SEGLSGTPGYMAPEYIERREIGPRNDVFAAGVLLVELLAGRPLGREGGVKKILERTCS
                     TPVALPAGCPPVDEALAAIALRAAALDPLARFADAAEFRAALETWLRPADEDAGAGAE
                     AKPGAVDFLMRRMKHRGDFPALSESVVAINRIAASESESVGTLSALILRDFGLTNKLL
                     RVVNSAHFRPAGGGRISTISRAVVVLGFDAVRNIAITVLLFEHLQNKTNASQLQEEFL
                     RACLAGLFARELAQRLRLRDSEQSYICAVFHNLGRLLCQFYFPEESEDIRRVVQQHGC
                     SEEIAAQRVLGAGLEELGIALARAWGFPELIQNSMRALPEGAVHPPRTADERLQALAA
                     CANACCDAVSRLAPAERERALADIAARFDEAVPVPAREMRERLLTAVDELGEFARVVK
                     VSLAQTRFGRNLRHFIDGSAPAENARADATLMPASALLEQSLPAEGGAEGQRAADPQA
                     VLSAGIQDISNTLVEDFRLNDVLRIILETMYRAMGFKRVLLCVRDARTNTMCGRFGFG
                     PEVGELARQLRFSLAAQPDNVFNVATARGVDVLISDVDDPKIAARVPAWYRKSVAART
                     FVLFPLTIKARPVAMIYADKDRPGELRISEQELAMLRTLRNQAVLAIKQAG"
     gene            complement(6190..7374)
                     /locus_tag="P5537_13475"
     CDS             complement(6190..7374)
                     /locus_tag="P5537_13475"
                     /EC_number="1.1.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004317754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016901 - oxidoreductase activity, acting
                     on the CH-OH group of donors, quinone or similar compound
                     as acceptor [Evidence IEA];
                     GO_function: GO:0070968 - pyrroloquinoline quinone binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PQQ-dependent sugar dehydrogenase"
                     /protein_id="HRV79095.1"
                     /translation="MQDGKVRELPGVRKRARGLLRVALVVGALAAGSTLAPRAAANGM
                     LYPSEAGPLRVTEVARGLESPWALAFLPDGRLLVTERPGRMRIIDTDGRVSEPVAGVP
                     EVHARGQGGLLDVVIGPDFARDRVVVFSYAEPTARGARTAVARARLDVDGLRLEGVQR
                     IFAQDEDPSGNHHWGSRLVFARDGRLFVTLGDRFHHRERAQALDSHLGKVVRIEPDGG
                     VPADNPLAGRADARAEIWSWGHRNVQGAALHPLTGELWTHEHGPQGGDEVNRTLAGRN
                     YGWPEITYGREYVTGRKIGAGSERADVAAPVLQWTPSIAPSGMAFYTGDAFPQWQGNL
                     FVGALKFQLLARLVLDGERVVHEERLLEGLGRIRDVRQGPDGRLWLLDESAGRVLRID
                     PQ"
     gene            7516..7863
                     /locus_tag="P5537_13480"
     CDS             7516..7863
                     /locus_tag="P5537_13480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79096.1"
                     /translation="MPASVRTLLRVLFIAALGGAFWLALMPIEPVIKLFSWQDKVEHA
                     LLFAGLAILGIAAWPRRAGVLAAGLLAYGAAMEVAQSTTAYRVGDPLDWLADAVGLLV
                     LLPFVLRRKTGAG"
     gene            7993..8853
                     /locus_tag="P5537_13485"
     CDS             7993..8853
                     /locus_tag="P5537_13485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79097.1"
                     /translation="MALITGAVMAKPDPETHLLVAALARRGIVADVLPWSSEQDWAAY
                     PLVVVRTPWDYFRHLDAFLAWAERTSALTQLVNPVTVIAWNSHKGYLRELAADGVATV
                     PTLWIERAAAAPGARLAAPGWDEVVVKPAVSIGAIGALRARADDPACLAHLESLVAEG
                     DVMVQPFVRSIAEAGEMSLIYFGGVFSHAICKRPAAGDYRVQDMYGGTVHAHTPTMAE
                     RTLAEAVLQHAPAATSYARVDLVSHEGRPVLMELEAIEPELFLGATPDAAANFAAELA
                     RQLEVAQARG"
     gene            8994..10952
                     /locus_tag="P5537_13490"
     CDS             8994..10952
                     /locus_tag="P5537_13490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HRV79098.1"
                     /translation="MSTDRHTLELLAPAKTADFGIEAINHGADAVYIGGPAFGARSSA
                     DNSVEDIARLVQHAHRYHAQIFVATNTILFDDELEPARKLIWQLFDAGVDALIVQDMG
                     LLELDLPPIQLHASTQTDIRDASKARFLQDVGFSQIVLARELSLAEVRKIAAATTCQL
                     EYFVHGALCVAFSGQCYISHAHTGRSANRGECSQACRLPYDLKDKDGHTVASNQHMLS
                     MKDNNQSANLRALAAAGVSSFKIEGRYKDLSYVKNITAHYRSLLDDILAHPDADGPAW
                     RRASSGRTTFFFTPQADKTFNRGYTDYFTNDRRHGIEAFESPKFVGEPIGRVKKIDTK
                     GRKFFDVERVAPIHNADGLSWYDPKGELTGLRVNRSEPNGGGEGIDRIFPSEPLPPDL
                     VPGTSLFRNHDHEFERALEKKSAERRIRVDARFATTTDGFALTLTDEDGVAATATLAA
                     AFEPAQNAERALATLREHLGKFGNTIFTTGEIELDLPAAPFLPASQLNALRREAVEQL
                     EAARLKAHARPPRAAAVEPPVPYPQDALSYLANVSNDQARAFYARHGVKLIDAAYEAN
                     EERDDVSLMITKHCLRYSFNLCPKEVKGIRPDPMQLVNGDETLTLKFDCKRCEMHVIG
                     ALRPHVARMRDTVVAHKVSFVPRSVSRN"
BASE COUNT         1655 a         4091 c         3753 g         1532 t
ORIGIN      
        1 acgttgccga aggtctcggt gaggctggga aacaggaaca ggtctgccga cgcgtaatgc
       61 gcggcgaggt cctcgccgtg acgcatgccg acgaagacgg cgtcggggtg ggcgcgcgcc
      121 agcgccgcgc gctgcgggcc gtcgccgacg aggatcatgc gcgcgtccgg gcgcaggcga
      181 cggatcgcgg cgaaggcgcg cagcgcgagg gcgaggttct tctccggcgc caggcgaccg
      241 acactgatca ccgccagtcc gcccgcaggc acgccccagg cgtgccgcaa ggcctcgtcg
      301 cggcgcgccg gcgaatacag cgcggtgtcc accccgcgcg agatcacctc cacgctgcgg
      361 tagccctgcg cggagagctg cgccgccagc gccgcggtgg gtacgaaggt gacggcgctg
      421 cggttgtgga aacggcgcag gtaggcggcc accggctggc gcagccagcc catgccgtag
      481 tggccgctgt agtggtcgaa gttggtgtgg aagtcggagc tgaccgggat gcgcagcttg
      541 ttggctgcgg tgaccgcggt ccacccgagc ggcccctcgg tcgccacatg gaccaggtcc
      601 gggcgctggc gcgaccactc gcgcagcaag cgcacgcgcg caggcaggcc gagcttgagg
      661 ccgtcgtagc gcggcaggcg caggccgcgg gcgagcacct cctccagccc tcctccgtgc
      721 aacgcggtct cgccgggctg ctggcgcgga cggatgagct gcacgccatg gccgcggcgg
      781 atgaggccgt cgaccatgcg ccccagggtc atggccacgc cattgacctc gggcgcccag
      841 gtctcggtca ccagggcgat gcgcagacgc ggcgcgcggc agaggtcttc ggtggtgtag
      901 tcgagcgttc tcatggcccc gcagactagg ggggccgtga gacagcggtg ttacgccggc
      961 attgccgcga gcttaccgag gctcgtgccg gcgggatggg gcttcagcgc acaggcgcat
     1021 cgagggcggc gacgatggcc gcgtcgtagc cgtagatgtc gttgcgcagc aagaccttgc
     1081 ccgcatcgtc gagcgccgcc gtggcgtagt gcagcagcac cttgacgtcg cgccccacgt
     1141 ccagggtgcg ggtgcgcccg ctgtcgagcg ccgcctgcag cgcctgcgcg ctccagcgct
     1201 cggcgtcggc gagcagcacc accgccagtt cctcgggctt ctccacgcgc acgcagcccg
     1261 agctgagcgc gcgctcggcg cgcttgaaca acgagcgcgt gttggtgtcg tgcaggtaga
     1321 tcacgtaggg attggagagc gagaacttga tccgcccgag cgagccgctg gcgcccgact
     1381 gctgctcgat gcggtagggg aagccgctct ggcgcgctcc gctccagtcg atggtggacg
     1441 ggtcgacggt ctgcccgctg cgatcgacca cgcgcatgcg acggttggcg agataggacg
     1501 gattgcgcgc cgccccgggg atcacgtcct cgcgcaggat ggtgggcggc accacccact
     1561 tggggttgag caccaggtgg gtgacgctgt cgagcaacga gggcgtgcgc cgcctcggct
     1621 tgccgacgat cacccgcgag gcccacaccg gctggccgtc gagcaccagg tcggcgtgat
     1681 agccgacgat gtcgaccagc aggcggtcgc cctggaggtc acccgccacc cagcgcaggc
     1741 gctcgaggtt ggcgcggatc tgcgcgacac gttgcgccgg gctggcgttg agcgcctcga
     1801 gagtctgcgc ccccagcacg ccgtcggcct gcaggccgtg cgcggcctgg aagcgctcga
     1861 ccgcctcgac cagggcctcg tcgtagtgcg acttgtcgcg cgcatcgagg acgctctcgc
     1921 ccgcggcggc caggcgggcg cgcagcgagg gcacgcgcgc gctgcgcgct ccgggcttga
     1981 gcgtcggccc ggcggcgacc cttggccagt cgccgccggc gagcagtcct tgctgagcga
     2041 gcagctcggc gcgcagcgcg cggtagagcg gcagatcggg cgcctgcgcc tccaccgccg
     2101 cggcgaggtc gggcgcctgc agcacgcgcg cgagttcgcc cgcacgctcg taggggttgg
     2161 gcggcggagt gaagttccac tcgcggtaga gcgcgtgcgg atcgaccttg ccgtaacgga
     2221 gctggaagag cagcgcggcc agggtgtcgg tgaatagcag ctcacgctcg gccgcgcggt
     2281 cggggtcggc ttcggcgggc agtgccgcac gcaggcgcag cggcgcgaaa tcggccggat
     2341 ccaggccatg tccacgcaag gcgtcgaccg cggcaagcag cgcctcggcg cgtgcgggct
     2401 cggtccacac cggacgatat gcgcgcgcga gatagaacaa tgcggtggtc tcgtcggcca
     2461 tcgcggcacg ctcgcgcagg cgctgctcga tacgcagcgc gagcgcggaa tcacccgtgg
     2521 ccggctcgat cgccacgggc gcggcctccc cggccgccat cgcgtgcacg ccgggtgcaa
     2581 gcagggcaag cgcagccagg gtcgcgaaag ttacaaaact tttacccagc ccgggcttgc
     2641 tttggattag gatccgatcc tcaagtgctt gttcggattg cttattattc atgtccaaga
     2701 tcatcccgaa tcaggtcgta ccgcatcgcc gcctgttgct gaagggtctc gccaccctgc
     2761 cgatgggcct ctcggccgct gcagcccagg ccgcccgcga cccgcatctc gccttccgcc
     2821 acacccacac cgaagaacgc ctgcgcgtcg cgttccgcaa ccgccaggga tacatccagc
     2881 ctgccctgca acgcatggac tggctcctgc gcgacttccg gactggagag tctacacgca
     2941 tggatcccag gctctatgac atgcttcacg cattgagcct cgcttgcggc ggcgacacct
     3001 tcgagatcat ctccggttac cgctcgccca ccaccaacac catgctgcgc aagacgcgcg
     3061 gcggcggcgt ggccaagcgc agcctgcaca tggacggcaa ggcgatcgac atccgcctgg
     3121 tgggcgtcga caccgcccgc ctgcgcgacg ccgcgctcgc gctcggagcc gggggggtgg
     3181 gctactatcc cgactccgac ttcgtccaca tcgacaccgg cccggtgcgc agttggggtc
     3241 cgaagtcggc ctgaccccgc gccgccccag cgcggggcgg tcgtttcatc gcagcagcaa
     3301 gccccacacc acggcagcgt tgagcagtgc gaccagcacc gccgcgctgc cgacgtcctt
     3361 tgcgcgcttg gccagctcgt gacgctcaag cgacacccgg tcgaccgtcg cctccaccgc
     3421 cgagttcagc agctccacca ccagcaccag cagcacgctg ccgatcatca gcgcgcgctc
     3481 gatcgccccc tcgcccagcc acagcgcgag cggaaccgcg accagggtga gccatatttc
     3541 ctggcgaaag gcatcctcgt gccggtaggc tgcgcgcagt ccatccatcg aatagcgggc
     3601 cgcgttgagg atccggcgca gaccggtctt gcccttgaaa ggactctcca tcctggctca
     3661 cccatccatg ctcgaaaggt ccgcgatcat gccacgaatc cgcggcatgg cccgcgccgt
     3721 ggcgccgttc ccacattccc cctccgcgac cgcggcggga ggcgtgcgat gacgcgcacg
     3781 atcggccgct tcgagatccg ccgcgagctt ggccgcggcg cgcaaagcgt cgtgcacctc
     3841 gcctgggatc cgcagctcga acgcgaggtg gcgctcaagg cgctccacct cggcccccgc
     3901 cccggtcacg acaacgcctc gctgctcgcc gaggcgcgcg cggtgagccg gttgcgccac
     3961 cccggcatcg tgccggtgtt cgaggccggc gaggacggcg gcgatcccta tctggtgttc
     4021 gagtacgtgc ccggcgagag cctcgccgcc ctgctcgacc ggcgcggggc cctgcccgcc
     4081 ggcgaggcgg tcgagcgcat gctggaggtg ctcgccgcgc tcgccgaggc gcacgcccag
     4141 ggcgtgatcc atcgtgacct caagccgagc aacgtactgc tcgacgccgc cggacacgcg
     4201 cgcgtgatgg acttcggcat cgcccgccgc gtcgaggccg cgggcgccag cgagggcctc
     4261 tccggcaccc cgggctacat ggcgcccgag tacatcgagc gccgcgagat cggcccgcgc
     4321 aacgacgtct tcgccgccgg cgtgctgctc gtcgaactgc tcgccggccg cccgctcggg
     4381 cgcgagggcg gcgtgaagaa gatcctcgag cgcacctgca gcacgccggt ggccctgccc
     4441 gcgggctgcc cgccggtcga cgaggccctc gccgcgatcg cgctgcgcgc cgccgcgctc
     4501 gacccgctcg cgcgcttcgc cgacgccgcc gagttccgtg ccgcgctcga gacctggctg
     4561 cggccagccg atgaggatgc cggcgccggg gccgaagcca agcccggcgc ggtggatttc
     4621 ctcatgcgcc gcatgaagca ccgcggcgac tttcccgcgc tgtccgaatc ggtggtggcg
     4681 atcaaccgca tcgcggcgag cgaatccgag agcgtgggca cgctgtcggc gctgatcctg
     4741 cgcgactttg gcctcaccaa caagctgctg cgggtggtga actcggcgca tttccgcccg
     4801 gcaggcggcg ggcgcatcag caccatctcg cgcgcggtcg tggtgctcgg cttcgacgcg
     4861 gtgcgcaaca tcgcgatcac cgtgctgctc ttcgagcacc tgcagaacaa gaccaacgcc
     4921 agccagctgc aggaggagtt cctgcgcgcc tgcctggcgg gcctgttcgc gcgcgagctc
     4981 gcccagcgcc tgcgcctgcg cgacagcgag cagagctaca tctgcgcggt gttccacaac
     5041 ctcgggcggc tgctgtgcca gttctacttt ccggaggaaa gcgaggacat ccgccgcgtc
     5101 gtgcagcagc acggctgcag cgaggagatc gcggcgcagc gcgtgctcgg cgccggcctg
     5161 gaggagctcg gcatcgcgct cgcccgcgcc tggggctttc ccgagctcat ccagaacagc
     5221 atgcgcgccc tgcccgaggg cgcggtgcat ccgccgcgca ccgccgacga gcgcctgcag
     5281 gccctcgccg cgtgcgccaa cgcctgctgc gacgcggtgt cgcgcctcgc cccggccgag
     5341 cgcgagcgcg cgctggccga catcgccgca cgcttcgacg aggccgtgcc ggtgccggcg
     5401 cgggaaatgc gcgaacgcct gctcaccgcg gtcgacgaac tcggcgagtt cgcccgcgtg
     5461 gtcaaggtga gcctcgcgca gacgcgcttc gggcgcaacc tgcgccactt catcgacggc
     5521 agcgcgccgg cggagaatgc ccgtgcggac gccacgctga tgcccgcctc cgccctgctc
     5581 gagcagtcgc tgcctgccga gggcggcgcg gaaggacagc gcgccgccga tccgcaggcg
     5641 gtgctgagcg ccggtatcca ggacatcagc aacaccctgg tcgaggactt ccgcctcaac
     5701 gacgtgctgc gcatcatcct cgagaccatg taccgcgcga tgggcttcaa gcgcgtgctg
     5761 ctgtgcgtgc gcgacgcgcg cacaaacacc atgtgcgggc gctttggctt cggccccgag
     5821 gtgggcgagc tcgccaggca gttgcgcttc agcctcgccg cccagcccga caacgtcttc
     5881 aacgtggcca ccgcgcgcgg cgtggacgtg ctgatcagcg acgtggacga cccgaagatc
     5941 gccgcccgcg tgccggcgtg gtaccgcaag tcggtggcgg cgcgcacctt cgtgctgttc
     6001 ccgctgacga tcaaggctcg cccggtggcg atgatctacg ccgacaagga ccgccccggc
     6061 gagctgcgca tcagcgagca ggagctcgcc atgctgcgca ccctgcgcaa ccaggcggtg
     6121 ctcgcgatca agcaggcggg ctgaggccgg ccatggcccg cagaccgccg gcttcggtgc
     6181 ggcgccggct cactgcggat cgatccgcag cacccgcccc gcgctctcgt cgagcagcca
     6241 caggcggccg tccggcccct ggcgcacgtc gcggatccgg cccaggcctt cgagcaggcg
     6301 ctcctcgtgc accacgcgct cgccatcgag caccaggcgg gcgagcaact ggaacttgag
     6361 cgcgccgacg aagaggttgc cctgccactg cgggaaggcg tcgccggtgt agaaggccat
     6421 gcccgagggc gcgatcgagg gcgtccactg cagcaccggc gccgccacgt ccgcgcgctc
     6481 gctgccggcg ccgatcttgc ggccggtgac gtattcgcgg ccgtaggtga tctccggcca
     6541 gccgtagttg cgcccggcga gcgtacggtt cacctcgtcg ccgccctgcg ggccgtgctc
     6601 gtgggtccac agctcgccgg tgagcggatg cagggccgcg ccctgcacgt tgcggtggcc
     6661 ccaggaccag atctcggcgc gcgcgtcggc gcgcccggcg agcgggttgt cggcgggcac
     6721 gccgccgtcg ggctcgatgc gcaccacctt gccgagatgg ctgtcgagcg cctgggcgcg
     6781 ctcgcgatgg tggaagcggt cgcccagggt cacgaacagg cgtccgtcgc gcgcgaacac
     6841 caggcgcgag ccccagtggt ggttgcccga ggggtcctcg tcctgcgcga agatgcgctg
     6901 cacgccctcc aggcgcaggc cgtcgacgtc gagccgcgcg cgcgccaccg cggtacgcgc
     6961 gccgcgcgcg gtcggctcgg cgtaggagaa caccaccacg cggtcgcggg cgaagtcggg
     7021 cccgatcacg acgtcgagca ggccgccctg cccgcgcgca tggacctcgg ggacgccggc
     7081 gacgggctcc gagacgcgcc cgtccgtatc gatgatgcgc atgcgcccgg ggcgctcggt
     7141 caccaggagg cgaccgtcgg gcaggaaggc gagcgcccag gggctctcca ggccgcgcgc
     7201 gacctcagtg acgcgcagcg ggcccgcctc gctcgggtac agcatgccgt tggcggcagc
     7261 gcgcggggcg agcgtgctgc cggcggcgag cgcgccgacc accagcgcga cacgcagcag
     7321 accgcgcgca cgcttgcgca cgccaggaag ttcgcgaacc ttgccatcct gcatcgggtc
     7381 atctccccag gttctgccgc agcgcaccac gcgccgcggc tttgccgcta agctgctccg
     7441 gtcctgcgcg ccgcaccgca cgccacgcag tctcacgcgc accacgaccg ttcatcgact
     7501 tttctgggac caccgatgcc cgcatccgtt cgcacgctgc tgcgcgtgct cttcatcgcc
     7561 gccctcggcg gcgccttctg gctcgcgctg atgccgatcg agccggtgat caagctgttc
     7621 tcctggcagg acaaggtcga gcacgccctc ctcttcgcgg gcctcgcgat cctcggcatc
     7681 gccgcctggc cgcgacgcgc cggcgtgctc gcggccgggc tgctcgccta tggcgcggcg
     7741 atggaggtgg cgcagtcgac caccgcctac cgcgtcggcg acccgctcga ctggctggcc
     7801 gacgcggtcg ggctgctggt cctgctgccc ttcgtgctgc gccggaagac gggcgcgggc
     7861 tagcaccctt atcgctccac gcctcgctcc gatagactcg gtacccacat gcgggcccct
     7921 gtgcgcgctc gccacctccc gaaccgccca gccccccgac agcccagccc ccttatgcca
     7981 aaccttcccc gcatggccct catcaccggc gccgtgatgg ccaagccgga ccccgaaact
     8041 cacttgctcg tggcagccct cgcgcggcgc ggcatcgtgg ccgacgtact gccctggagc
     8101 agcgagcagg actgggccgc ctaccccttg gtggtggtgc gcacgccctg ggactacttc
     8161 cgccacctcg atgctttcct ggcctgggcc gagcgcacca gcgcgctcac ccagctcgtc
     8221 aacccggtga cggtgatcgc ctggaacagc cacaagggtt acctgcgcga actcgcggcc
     8281 gacggcgtcg cgaccgtgcc cacgctgtgg atcgaacgcg ccgccgccgc cccaggtgcg
     8341 cgactggccg cgccgggctg ggacgaggtg gtggtcaagc ccgcggtgtc gatcggtgcc
     8401 atcggcgccc tgcgcgcccg agccgacgac cctgcctgcc tggcacatct ggagagcctg
     8461 gtcgccgagg gcgacgtcat ggtccagccc ttcgtgcgca gcatcgcaga ggcgggagag
     8521 atgtcgctga tctacttcgg cggggtcttt tcgcatgcca tctgcaagcg ccctgcagcg
     8581 ggggactacc gtgtgcagga catgtatggc ggtacggtgc atgcgcacac gccgaccatg
     8641 gccgaacgca cgctggccga ggccgtgctc cagcatgcgc ccgcggcgac aagctatgcc
     8701 cgggtcgacc ttgtgagcca tgagggccgg cccgtgctga tggagctgga ggcgatcgag
     8761 cccgaactct tcctcggcgc cacgccggac gcagcggcga acttcgcggc cgagctggca
     8821 cgccaactcg aggtggcgca ggcgcgagga taggctgccg gggcgccgag caacggatcg
     8881 agccttcgca cgctccggcg gcgcgcgctt ttttcccaca ggcacacctg ccggggcgcg
     8941 gcttgctatc atcgcgccct taccaatcaa acgcttgcgc actccatacg ccgatgagca
     9001 ccgaccgcca caccctcgaa ctcctcgccc cggccaagac cgccgacttc ggcatcgaag
     9061 ccatcaacca cggcgcggac gcggtctaca tcggcggccc ggccttcggc gcacgctcgt
     9121 cagcggacaa ctcggtcgag gacatcgccc gcctggtgca gcacgcccac cgttaccacg
     9181 cgcagatctt cgtcgccacc aacaccatcc tgttcgatga cgagctcgag ccggcgcgca
     9241 agctgatctg gcaactcttt gacgccggcg tcgacgccct gatcgtgcag gacatgggcc
     9301 tgctcgagct cgacctgccg ccgatccagc tccacgccag cacccagacc gacatccgcg
     9361 acgccagcaa ggcgcgcttc ctgcaggacg tgggcttctc gcagatcgtg ctcgcgcgcg
     9421 agctgtcgct cgccgaggtg aggaagatcg ccgcggcgac cacctgccag ctcgaatact
     9481 tcgtgcacgg cgcgctgtgc gtggccttct ccggccagtg ctacatcagc cacgcccaca
     9541 ccgggcgcag cgccaaccgc ggcgaatgct cgcaggcctg ccgcctgccc tacgacctca
     9601 aggacaagga cggccacacc gtcgccagca accagcacat gctgtcgatg aaggacaaca
     9661 accagagcgc caacctgcgc gcactggccg ccgcgggcgt gagctcgttc aagatcgagg
     9721 gtcgctacaa ggacctctcc tacgtcaaga acatcactgc ccactaccgc agcctgctcg
     9781 acgacatcct cgcgcacccg gacgccgacg gccccgcctg gcgccgcgcc tccagcgggc
     9841 gcaccacctt cttcttcacc ccgcaggccg acaagacctt caaccgcggc tacaccgact
     9901 acttcaccaa cgaccgccgc cacggcatcg aggccttcga gtcgcccaag ttcgtcggcg
     9961 agccgatcgg ccgggtaaag aagatcgaca ccaaggggcg caagttcttc gacgtcgagc
    10021 gcgtggcgcc gatccacaac gccgacggct tgagctggta cgaccccaag ggcgagctca
    10081 ccggcctgcg ggtgaaccgc tccgagccga acggcggcgg cgaaggcatc gaccgcatct
    10141 tcccgtccga gccgctgccg cccgacctcg tgccgggcac ctcgctgttc cgcaaccacg
    10201 accacgagtt cgagcgcgcg ctggagaaga aatccgccga gcgccgcatc cgcgtcgatg
    10261 cacgcttcgc caccacgacc gacggcttcg cgctgacgct gaccgacgag gacggcgtcg
    10321 ccgccaccgc caccctcgcc gccgccttcg agccggcgca gaacgccgag cgcgcgctcg
    10381 ccaccctgcg cgagcacctc ggcaagttcg gcaacacgat cttcaccacg ggcgagatcg
    10441 agctcgacct gcccgccgcg cccttcctgc ccgcgagcca gctcaacgcc ctgcgccgcg
    10501 aggcggtgga gcaactggag gccgcacggc tgaaggccca cgcccgtccg ccgcgcgcgg
    10561 cagccgtcga gccgccggtg ccctacccgc aggacgcgct gagctacctc gccaacgtct
    10621 cgaacgacca ggcgcgcgcc ttctacgcca ggcatggcgt caagctcatc gacgccgcct
    10681 acgaggcaaa cgaggagcgc gacgacgtct cgctgatgat caccaagcac tgcctgcgct
    10741 acagcttcaa cctgtgcccg aaggaagtga aaggcatccg ccccgacccg atgcagctgg
    10801 tcaatggcga cgagacgctg acgctgaagt tcgactgcaa gcgctgcgag atgcacgtga
    10861 tcggcgcgct gcgtccgcat gtcgccagga tgcgcgacac ggtggtggcg cacaaggtga
    10921 gcttcgtgcc acgcagtgtg tcgcgaaact gacctgcacg ccggcatgcg cgcgtgaccc
    10981 tggtcacggg gtgcgcactt tcctgcaggc agcggctgtg gaaagcccta g
//
LOCUS       DAOTIN010000110        10822 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_7225_length_10822_cov_10.115724, whole genome shotgun
            sequence.
ACCESSION   DAOTIN010000110 DAOTIN010000000
VERSION     DAOTIN010000110.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 10822)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 10822)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10822
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_7225_length_10822_cov_10.115724"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..730)
                     /locus_tag="P5537_13495"
     CDS             complement(<1..730)
                     /locus_tag="P5537_13495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proton-conducting transporter membrane subunit"
                     /protein_id="HRV79099.1"
                     /translation="MSLALIVLLPFIGALFPALMIRAGRSACATTAFVFPLLALVLLL
                     AQAPAVFRGEVLVAGWDWVPALGLQASFFLDGLGMFFAGLILGIGLLVIVYARFYLAK
                     NDPMGVFYSYLLLFQGAMVGVVLSDNILLLLVFWELTSLSSFLLIGYWKHLPEGRQGA
                     RMALTVTGAGGLAMIAGMLILGDIAGSWNLTDILRNKEAIQASPLYVPALVLILAGCF
                     TKSAQFPFHFWLPHAMAAPTPVSAY"
     gene            955..1752
                     /locus_tag="P5537_13500"
     CDS             955..1752
                     /locus_tag="P5537_13500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HRV79100.1"
                     /translation="MQPKKTESAPSAEGKTSIQVIERMMKLLDVLAEHADPVQLKQLA
                     LETGLHPSTAHRILGAMTQSGFVERSDAGAYRLGIRLLELGSLVKSRISLRETAMPFM
                     LKLHAATGESVNLGVRAGDEIVYVERTSSGRASVRVVHIVGARAPLHTTATGKLFLVE
                     DGLERIRDYARRTGLPASTPASITALPALEKELDRVRRHGVAFDLDEVESGVRCIAAG
                     IRDDGGELIAGLSLSTPSERFNPDWAPLVRETADEISRALGHLPPKA"
     gene            complement(1764..2378)
                     /locus_tag="P5537_13505"
     CDS             complement(1764..2378)
                     /locus_tag="P5537_13505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HRV79101.1"
                     /translation="MTITNIAVCGIGGQGVMTATEILAEAALSLGFDVKKTEVAGMSQ
                     RGGVVTSHLRFGPQVLSPQIMPGEADLLVGFEAAEALRWAHMLKPGGVALVNQGRFVP
                     PVVTIGLYDYPEDPIAEMRRLGLAVFDFDASALAMQLGNIRLGNTVMLGAMSDRLPFP
                     ADVLRKAVLDRFGTRKPELLELNREAFELGRAAVAQPAPAQAIA"
     gene            complement(2389..4263)
                     /locus_tag="P5537_13510"
     CDS             complement(2389..4263)
                     /locus_tag="P5537_13510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HRV79102.1"
                     /translation="MGAALPETAPSRLFLSGNEAVALAVRDAGCRVAAAYPGTPATEI
                     LEELSRFPDLYTEWSVNEKVSLEVALGASMVGARAFCAMKHVGLNVAADALMTMTVTG
                     TEGGLVIAVADDVGMSSSQNEQDSRFWARFAHLPLFEPADAQESYDMAREAFAVSERF
                     RCPAIVRMTTRICHVKGRVVPAEREAHEPAGFVKDPQRWVMVPGHAKPRVALMYEREE
                     ALRASAQQSPFNVLVEGGDRRIGFVTSGPAYMHVRETFPDAPVFKLGQSYPLPLERLR
                     AFAAGVDQLLVVEETEPLVESELRAAGIACAGKDVLPRVGELSPDRLRPAVARLRGEE
                     VPASAQPRLVPQQVFPRPPTMCVACPHLGIYYTLAQLRNLTISGDIGCYTLGAGHPWN
                     ALDTCISMGASMGVALGMDKGRGPADAKKAVIAVIGDSTFMHMGMQGLLDITWNRGNV
                     TVLLLDNRAVGMTGGQDNPGTGRDIHGESAQRVDFAKLCEALGVKKERIHTLDPYELP
                     TLFKTLRDEIKVPEPSVIITDRPCVLIDDYKPTQPYKVIADKCTGCANCIDVGCPAIH
                     VTRRETQVKPSGKEVELAFVRIETSACTGCGLCVQPCAPEAIVHALPEHPVKFLHAKI
                     "
     gene            4486..5820
                     /locus_tag="P5537_13515"
     CDS             4486..5820
                     /locus_tag="P5537_13515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018608545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate--CoA ligase"
                     /protein_id="HRV79103.1"
                     /translation="MLKERWNDRAGGFHPVSAPDFLPRQQLREVQSHRLQAVVGRAWD
                     KVALFRERMQARGLTPDSIAGIGDIAALPFTTKADLRDTYPFGLFASPMDEVVRLHAS
                     SGTTGKPIVVAYTREDIEVWTEAMARTFAACGLHRGDILQNAFGYGLFTGGMGTHYGA
                     EAIGAAVIPVSGGNTERQIMLMRDFGVTAVCATPSFFVHLVEKAGEMGVDLRDLPLRT
                     GVFGAEPWTDGMRERIQAETGIEAFDIYGLSEITGPGVATECACHDGLHVLEDHFFPE
                     IIDPATGAALPDGEEGELVLTTLSKRAMPMIRYRTRDITAILTAPCGCGRTMRRIRRI
                     SRRSDDMFIIRGVNVFPSQVEAALLAVEGTVPHYQIVLTREHGLDRMTVEVEVTPEVF
                     SDTVRAMEELRARIGHAIEHVLGIRVGLRLVGPHSIPRSEGKARRVIDKRQD"
     gene            5835..6260
                     /locus_tag="P5537_13520"
     CDS             5835..6260
                     /locus_tag="P5537_13520"
                     /inference="COORDINATES: protein motif:HMM:NF040320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid-binding protein"
                     /protein_id="HRV79104.1"
                     /translation="MKISQLSVFLENRPHSLLEPLQALAAAGIDLSGIALADSEQFGI
                     LRLVLRDWARARGLLQSGGWAVTVTDMVAIHVEDQPGGLVRILEVLAAAGADIEYMYG
                     FFVRRSGRVAMLFRFARPELAIAALEAAGITMLGEDALY"
     gene            complement(6376..7542)
                     /gene="pbpG"
                     /locus_tag="P5537_13525"
     CDS             complement(6376..7542)
                     /gene="pbpG"
                     /locus_tag="P5537_13525"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009002 - serine-type D-Ala-D-Ala
                     carboxypeptidase activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine endopeptidase"
                     /protein_id="HRV79105.1"
                     /translation="MKVRPLIAAIAAMFALQSGMAVAAPKASGKAATSKVSKPAAKKA
                     AAKAPVRKAAAKPAQKKAAASKAVTRSAKATRSAKAGSRAVAGARGRAAPMRVSLRKP
                     AVAAAALAAPAAVLADEPDAPLALDGNGMPVLGSSAFYVINQRTGEVLLERNAAEVLP
                     IASITKLMTAMVVLDAGQSLSEPVVISEEDIDQLKGTGSRLALGTTLSREEMLQLALM
                     SSENRAASSLARHYPGGEAAFVEAMNVKARLLGLWNTRFHDSTGLNPANVSSPRDLAK
                     MVAASASYPLIREFSTAHERYVPVHGRMLRFGNTNSLVRSPEWTISVSKTGYISEAGR
                     CLVMQTWLHQQPVVMVLMDSYGRYTRTADAKRVRKWLEQTAPQRLAAAPQGAGS"
     gene            complement(7702..8847)
                     /locus_tag="P5537_13530"
     CDS             complement(7702..8847)
                     /locus_tag="P5537_13530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HRV79106.1"
                     /translation="MGADEGRAALVLTGGGARAAYQVGVLVAIRELRGKRPGNPFPIL
                     CGTSAGAINAVALAVHAADFGRAVLHIQRVWRSLHVAQVYRVDPPALFGSGLRWGAAL
                     FGGWLVRQTPRSLLDNTPLRGLLERVLDFASIEAAIGRGDLRALSVTASGYSSGESLA
                     FFQGAPELQPWRRAQRLGVRAQLDVCHVMASAALPFVFPAVKIHREYFGDGSMRQLAP
                     VSPAIHLGADRILVIGAGRTAEEGRMRAVGGYPSPAQIAGHALSSIFLDTLEVDLERL
                     ARINDTVSRLDETRRAEAGIALRPIECLVIQPSQRLDTIAARHAHSLPMQLRIVLRGL
                     GTLRRDGSTLLSYLLFEPGFTRALIELGYHDAMTRAGELRRFLRIDS"
     gene            complement(8998..>10822)
                     /locus_tag="P5537_13535"
     CDS             complement(8998..>10822)
                     /locus_tag="P5537_13535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HRV79107.1"
                     /translation="RERMKIPVFHDDQHGTAIVVGAAVLNGLHLQGKDLKKVKLVTSG
                     AGAAALACLGLLVKLGVPVENIWVTDLEGVVYEGRTALMDPIKARYAKKTDARKLAEV
                     IEGADVFLGLSAGGVLKGEMVAKMAANPLILALANPTPEILPDEVKAVRSDAIIATGR
                     SDYPNQVNNVLCFPFIFRGALDVGATTITDEMQLAAVKAIAELARVEQSDIVAAAYGE
                     KVGGFGPEYIIPRPFDPRLIVKIAPAVAEAGMASGVATRPITDWNAYRSQLNNFVWHS
                     GLIMKPVFAAAHKNPKRIIFSEGESEKVLRAVQQVVDEGLARPILIGRPEVVAKNIER
                     FGLRLAAERDFELVNPDSDPRFNQLWQHYHGLMERKGVSVEYAKKEVRRRTTLIGALL
                     LKFGYGDGLICGTYGMHRLHREFVEDVLGRREGVDNLYTVNLLSLPGRTLFLADTYVN
                     YDPTPEQVVEMTLLAAEEMKRFGIEPRIALLSHSSFGSADSPTAGKMRTAMRLLHERH
                     PELQVEGEMHGDSALDARHRLQIFPNAKMREDANLLIFPTLDAANIAFNLLKNAAGSG
                     MTVGPILLGAAKPVHILTPSATVRRIINMTALTVVEAGQAG"
BASE COUNT         1672 a         3683 c         3884 g         1583 t
ORIGIN      
        1 ggtaggccga caccggggtc ggcgccgcca tcgcgtgcgg cagccagaag tggaagggga
       61 actgcgcgct cttggtgaag cagccggcga ggatcagcac cagcgcgggc acgtacagcg
      121 gcgaggcctg gatcgcctcc ttgttgcgca ggatgtcggt gaggttccag gagccggcga
      181 tgtcgcccag gatcagcatg ccggcgatca tcgccagccc gccggcaccg gtcacggtaa
      241 gcgccatgcg cgcgccctgg cggccttcgg ggaggtgctt ccagtagccg atgagcagga
      301 aggacgacag gctggtcagt tcccagaaca ccagcagcag caggatgttg tccgacagca
      361 ccacgcccac catcgcgccc tggaagagca gcaggtagct gtagaacacc cccatcgggt
      421 cgttcttggc gaggtagaag cgcgcataga cgatcaccag caggccgatg cccaggatca
      481 gcccggcgaa gaacatcccc agcccgtcga gaaagaagct cgcctgcagg ccgagcgcgg
      541 gcacccagtc ccagccggcg acgagcacct cgccgcggaa caccgccggc gcctgcgcga
      601 gcagcagcac gagggcgagc agcggaaaga cgaaggcggt ggtcgcacag gcgctgcgcc
      661 cggcgcggat catcagcgcg ggaaagagcg cgccgatgaa gggcagcagc acgatcaggg
      721 cgaggctcat cggggggact cctcgggcgt tgtcggtggg atgggcgacg cgaaccgcgg
      781 gtggcggggg ccacccacac cccgcatgag gaccgcttcc gggcggagta tatcgatgat
      841 acgacccccg ccaaatcggg gttgatttca ctaggcgaaa tcggatcgca cgggtaccat
      901 tcgtcagact cccttgccag ccctggcaag cctccgatct ttccgcgaac ctccgtgcag
      961 ccgaagaaga ccgaatccgc ccccagcgcc gaaggcaaga cctcgatcca ggtcatcgag
     1021 cgcatgatga agctgctgga cgtgctcgcc gaacatgccg acccggtaca actgaagcag
     1081 ctcgcgctcg agaccggctt gcacccgtcc accgcgcacc gcatcctcgg cgcaatgacg
     1141 cagagcggct tcgtcgagcg ctcggacgcc ggcgcctatc ggctgggcat tcgactgctc
     1201 gagctcggca gcctcgtcaa gtcgcgcatc tcgctgcgcg agaccgcgat gcccttcatg
     1261 ctcaagttgc acgccgccac cggcgagagc gtgaacctgg gcgtgcgcgc gggcgacgag
     1321 atcgtgtatg tcgagcgcac ctcgagcggg cgcgcctcgg tgcgcgtggt gcacatcgtg
     1381 ggcgcgcgcg cgccgctgca caccaccgcc accggcaagc tcttcctggt cgaggacggc
     1441 ctcgagcgca tccgcgacta cgcccgccgc accggcctgc ccgcctccac cccggcctcg
     1501 atcaccgcgc tgccggcgct ggagaaggag ctcgaccgcg tgcgtcgcca cggcgtggcc
     1561 ttcgacctcg acgaggtcga gtccggcgtg cgctgcatcg ccgcgggaat ccgcgacgac
     1621 ggcggcgaac tgatcgccgg cctgtcgctg tcgaccccgt ccgaacgctt caaccccgac
     1681 tgggccccgc tggtgcgcga gaccgcggac gagatctcgc gcgccctcgg ccacctgccg
     1741 ccgaaggcgt gaggcggtag gcgtcaggcg atcgcctggg cgggggccgg ctgggcgact
     1801 gccgcgcggc cgagctcgaa ggcctcgcgg ttgagttcca gcagctcggg cttgcgcgtg
     1861 ccgaagcgat cgagcacggc cttgcgcagc acatcggccg ggaacggaag gcggtccgac
     1921 atcgcgccca gcatcacggt gttgccgagg cggatgttgc cgagctgcat cgcgagcgcg
     1981 ctggcgtcga agtcgaacac cgcgaggccg agcctgcgca tctccgcgat cgggtcctcg
     2041 gggtagtcgt agaggccgat ggtcaccacc ggcggcacga agcggccctg gttgaccagc
     2101 gcgaccccgc ccggcttgag catgtgcgcc cagcgcaagg cctcggcggc ctcgaagccc
     2161 accagcaggt cggcctcgcc gggcatgatc tgcggcgaca gcacctgggg gccgaagcgc
     2221 aggtgcgagg tcacgacccc gccgcgctgg ctcatgccgg ccacttcggt cttcttgacg
     2281 tcgaagccga gcgacaacgc ggcctctgcg aggatctcgg tggcggtcat cacaccctgg
     2341 ccgccgatgc cgcagacggc gatgttggtg atggtcattg cgggctcctc agatcttggc
     2401 gtgcaggaac ttcaccgggt gctccggcag ggcatggacg atggcctcgg gcgcgcacgg
     2461 ctgcacgcac aggccgcagc cggtgcaggc ggaggtctcg atgcgcacga aggcgagctc
     2521 gacttccttg cccgagggct tgacctgggt ctcgcgccgg gtgacgtgga tcgccgggca
     2581 gccgacgtcg atgcagttgg cgcagccggt gcacttgtcg gcgatgacct tgtagggctg
     2641 cgtgggcttg tagtcgtcga tcagcacgca gggccggtcg gtgatgatca ccgagggctc
     2701 gggcaccttg atctcgtcgc gcagggtctt gaacagcgtc ggcagctcgt aggggtcgag
     2761 ggtgtggatg cgctccttct tgacgccgag cgcctcgcac agcttggcga agtcgacccg
     2821 ctgcgcgctc tcgccgtgga tgtcgcggcc ggtgccgggg ttgtcctggc cgccggtcat
     2881 gcccaccgcg cggttgtcga gcagcagcac ggtgacgttg ccgcggttcc aggtgatgtc
     2941 gagcaggccc tgcatgccca tgtgcatgaa ggtggagtcg ccgatcaccg cgatcaccgc
     3001 cttcttggcg tcggccgggc cgcggccctt gtccatgccg agcgcgacgc ccatcgaggc
     3061 gcccatcgag atgcaggtgt cgagcgcgtt ccaggggtgg ccggcgccca gggtgtagca
     3121 gccgatgtcg cccgagatgg tgaggttgcg cagctgcgcg agggtgtaat agatgcccag
     3181 gtgcggacag gcgacgcaca tggtcggcgg gcgcgggaag acctgctgcg gtaccaggcg
     3241 gggctgggcg ctggcgggga cctcctcgcc gcgcaggcgg gcgaccgccg ggcgcaggcg
     3301 atcgggcgag agctcgccca cgcgcggcag cacgtccttg cccgcacagg cgatgccggc
     3361 ggcgcgcagc tcgctctcga ccaggggctc ggtctcctcg accaccagga gctggtcgac
     3421 gccggcggcg aacgcgcgca ggcgctcgag cggcagcggg taggactggc cgagcttgaa
     3481 caccggcgcg tcggggaagg tctcgcgcac gtgcatgtag gccgggcccg aggtcacgaa
     3541 gccgatgcgg cggtcgccgc cctcgacgag cacgttgaac gggctctgct gcgcggaggc
     3601 gcgcagggcc tcctcgcgct cgtacatgag cgccacgcgc ggcttggcgt ggccgggcac
     3661 catgacccag cgctgcggat ccttgacgaa gccggcgggc tcgtgggcct cgcgctcggc
     3721 cgggacgacg cggcccttga cgtggcagat gcgggtggtc atgcgcacga tcgccgggca
     3781 gcggaagcgc tcggacaccg cgaaggcctc gcgcgccatg tcgtaggact cctgcgcgtc
     3841 ggcgggctcg aacagcggca ggtgggcgaa gcgcgcccag aagcgcgagt cctgctcgtt
     3901 ctgcgacgag gacatgccga cgtcgtcggc gaccgcgatc accaggccgc cttcggtgcc
     3961 ggtgacggtc atggtcatca gcgcgtcggc ggcgacgttg aggccgacgt gcttcatcgc
     4021 acagaaggcg cgcgcgccca ccatcgaggc gccgagcgcg acctcgagcg agaccttctc
     4081 gttcaccgac cactcggtgt agaggtcggg aaagcgcgac agctcctcca ggatctcggt
     4141 cgccggggtg cccggatagg cggcggcgac gcggcagccg gcgtcgcgca cggcgagcgc
     4201 cacggcctcg ttgccggaca ggaacaggcg gctcggggcg gtttcgggca gggcagcacc
     4261 catggggaga tcctctctga cgggttcggg gtcgaaacgc acgagcttag tgagcgccct
     4321 gcccggctcc attgacgaag atcaaccgcg ctgcagtcgt gcgcgccgcg gagcgctcgt
     4381 cacgggcacg gatgctgcac ctgcacagct attgcgctcg atcaaacgcc gacttcctgt
     4441 gcaggtgcag catggcgtct tttgcctcga gcggaattcg acgagatgct caaagaacgc
     4501 tggaacgacc gtgcgggcgg cttccatccg gtcagtgcgc cggacttcct gccccgacag
     4561 caattgcgcg aggtgcaatc gcaccgcctg caggcggtgg tcggacgcgc ctgggacaag
     4621 gtggcgctgt tccgcgagcg catgcaggcg cgcggcctca cgccggactc gatcgccggc
     4681 atcggcgaca tcgccgccct gcccttcacc accaaggccg acctgcgcga cacctacccc
     4741 ttcggcctgt tcgccagccc gatggacgag gtggtgcgcc tgcacgcctc ctcgggcacc
     4801 accggcaagc cgatcgtggt cgcctacacc cgcgaggaca tcgaggtgtg gaccgaggcg
     4861 atggcacgca ccttcgccgc ctgcggcctg caccgcggcg acatcctgca gaacgccttc
     4921 ggctacggcc tgttcacggg cggcatgggc acccactacg gtgccgaggc gatcggcgcg
     4981 gcggtgatcc cggtctcggg cggcaacacc gaacgccaga tcatgctgat gcgcgacttc
     5041 ggcgtcaccg cggtgtgcgc cacgccgagc ttcttcgtgc acctggtgga aaaggccggc
     5101 gagatggggg tggacctcag ggacctgccg ctacgcaccg gcgtgttcgg cgccgagccg
     5161 tggaccgacg gcatgcgcga gcgcatccag gccgagaccg gcatcgaggc cttcgacatc
     5221 tacggcctgt ccgagatcac cggccccggc gtggccaccg agtgcgcctg ccacgacggc
     5281 ctgcacgtgc tggaggacca cttcttcccc gagatcatcg accccgcgac cggcgcggcg
     5341 ctgcccgacg gcgaggaggg cgagctggtg ctgaccacgc tgtccaagcg cgcgatgccg
     5401 atgatccgct accgcacccg cgacatcacc gccatcctca ccgcgccctg cggatgcggc
     5461 cgcacgatgc gccgcatccg ccgcatcagc cggcgctcgg acgacatgtt catcatccgc
     5521 ggcgtcaatg tctttccatc gcaggtcgag gccgcgctgc tggcggtcga gggcacggtg
     5581 ccgcactacc agatcgtgct cacgcgcgag catgggctgg accggatgac ggtcgaggtg
     5641 gaagtgacgc ccgaagtgtt cagcgacacc gtgcgcgcca tggaggagct gcgcgcgcgc
     5701 atcgggcacg cgatcgagca cgtgctcggc atccgcgtcg gcctgcgcct ggtcgggccg
     5761 cacagcatcc cgcgcagcga aggcaaggca cggcgcgtga tcgacaagcg ccaagattga
     5821 ggcaggagcc cgcgatgaag atctcccaac tttccgtctt cctggaaaac cgcccgcaca
     5881 gcctgctgga gccgctgcag gcgctcgccg cagccggcat cgacctgtcg ggaatcgcgc
     5941 tcgccgacag cgagcagttc ggcatcctgc gcctggtgct gcgcgactgg gcgcgcgcgc
     6001 gcgggttgct gcaatccggc ggctgggcgg tgacggtgac cgacatggtg gcgatccacg
     6061 tcgaggacca gcccggcggc ctggtacgca tcctcgaggt gctcgctgcg gcaggggccg
     6121 acatcgagta catgtacggc ttcttcgtgc gccgcagcgg tcgcgtggcg atgctgttcc
     6181 gcttcgcccg tccggagctg gcgatcgccg cactggaagc cgccggcatc acgatgctcg
     6241 gcgaggatgc gctgtactga agacgcgacg gttcatgccg gagcgcccga aggcgcgaac
     6301 acggcggctg ccgaaaaaaa agcggggccg gcccgatcgg gcggccccgc gtttcgacct
     6361 gcgcgcccgg gaagctcagc tgcccgcgcc ctgcggtgcg gcggccaggc gctggggtgc
     6421 ggtctgctcg agccacttgc gcacgcgctt ggcgtcggca gtgcgggtat agcggccgta
     6481 ggagtccatc agcaccatga ccaccggctg ctggtgcagc caggtctgca tgaccaggca
     6541 gcggcccgcc tcggagatat agccggtctt ggacacgctg atcgtccatt ccgggctgcg
     6601 caccagcgag ttggtgttgc cgaagcgcag catgcgccca tgcaccggca cgtagcgctc
     6661 gtgcgcggtg gagaactcgc ggatgagtgg ataggacgcc gaggccgcga ccatcttggc
     6721 gaggtcgcgt gggctggaga cgttggccgg gttgaggccg gtgctgtcgt ggaagcgggt
     6781 gttccacagg ccgagcaggc gcgccttgac gttcatcgcc tcgacgaagg ccgcctcacc
     6841 gcccggatag tgacgcgcca gcgacgaggc cgcgcggttc tcggacgaca tcagcgcaag
     6901 ctgcagcatc tcctcgcgcg acagcgtggt accgagcgcg agccgcgagc ccgtgccctt
     6961 gagctgatcg atgtcttcct cggagatcac caccggctcg gacaggctct gtccggcgtc
     7021 gagcaccacc atcgcggtca tcagcttggt gatcgaggcg atcggcagca cttcggcggc
     7081 gttgcgctcg agcagcacct caccggtgcg ctggttgatg acgtagaagg cgctggagcc
     7141 gagcacgggc atgccgttgc cgtcgagggc gagcggtgca tcgggctcgt cggcgagcac
     7201 cgccgcgggc gcggcgagcg cggcggcggc caccgccggc ttgcgcaggc tcacccgcat
     7261 cggcgccgcc cggccgcgag cacccgcaac cgcgcggctc ccggccttcg cggagcgcgt
     7321 ggccttggcg ctgcgcgtca cggccttgga cgcggcggcc ttcttttgcg cgggcttcgc
     7381 agcggccttg cgcaccgggg ccttggccgc agccttcttc gcggccggct tggaaacctt
     7441 gctcgtcgca gcctttccgg atgccttcgg ggctgcgacg gccatacccg actgcagcgc
     7501 gaacatcgcg gcaatcgcgg cgatcagtgg gcgaactttc atgatggcga cgggacggag
     7561 agcggtggaa tgcgggttcg aggcgttctg ctttaagaaa taggcagata cgcaatagat
     7621 ttcaagttgt ttctagcttt gggaggaatt ctacccctgc atcggcgtcg ccggcgagcc
     7681 cggcggccac cccgccccgg gtcaggagtc gatgcgcagg aaacggcgaa gctcgccggc
     7741 ccgcgtcatc gcgtcatgat agccgagctc gatcagcgcg cgcgtgaaac ccggttcgaa
     7801 aagcaggtag gaaagcaggg tcgaaccgtc gcgccgcaag gtgcccaggc cgcgcagcac
     7861 gatgcgcagc tgcatcggca ggctgtgcgc gtggcgcgcc gcgatggtgt cgaggcgctg
     7921 cgagggctgg atcaccaggc actcgatcgg gcgcagcgcg atccctgcct cggcgcggcg
     7981 ggtctcgtcg agccggctca cggtgtcgtt gatgcgcgcc aggcgctcga gatcgacctc
     8041 gagggtgtcg aggaagatgc tcgacagcgc gtggccagcg atctgcgccg gcgaaggata
     8101 gccgcccacg gcgcgcatcc tcccctcttc ggccgtacgc ccggcaccga tcaccaggat
     8161 gcggtcggcg ccgaggtgga tcgccgggct caccggcgcg agctggcgca tcgagccgtc
     8221 gccgaagtac tcgcggtgga tcttcaccgc cgggaacacg aagggcagcg ccgcgctcgc
     8281 catcacgtgg cagacgtcga gctgcgcgcg cacgcccagg cgctgcgcgc ggcgccaggg
     8341 ctgcagttcg ggcgcgccct ggaagaaggc gaggctttcg ccggaggagt agccggaggc
     8401 ggtgacgctg agcgcgcgca gatcgccgcg gccgatcgcg gcctcgatcg aagcgaagtc
     8461 gagcacgcgc tcgagcaggc cgcgcaaggg ggtgttgtcg agcagcgagc gcggggtctg
     8521 ccgcaccagc cagccgccga acagcgccgc gccccagcgc aggccgctgc cgaagagcgc
     8581 gggcggatcg acgcgataca cctgggcgac gtgcaggctg cgccagacgc gctggatgtg
     8641 cagcaccgcg cggccgaagt cggccgcatg caccgcgagc gcgaccgcgt tgatcgcacc
     8701 ggccgaagtt ccgcacagga tggggaaggg attgccgggg cgcttgccgc gcagttcgcg
     8761 gatcgcgacc agcacgccga cctggtaggc ggcacgcgca ccgccaccgg tcagcaccag
     8821 cgccgctcgt ccttcgtccg cgcccatccg cccgcccccg ctcatgcgat ggcttcagca
     8881 tcgcgcaacg acgaccgccc ccgcaaggaa ggaatgcgca gccgcgacgc gagccgcgcc
     8941 gggcgcgcac cccgagctgc ggggaacgcg cccttgcgcc cgcttgcggc gccccgctca
     9001 gcccgcctgg ccggcctcga ccacggtgag cgcggtcatg ttgatgatgc ggcgcacggt
     9061 cgccgagggc gtgaggatgt gcaccggctt ggccgcgccg agcaggatcg gccccaccgt
     9121 catgccgctg cccgcggcgt tcttgagcag gttgaaggcg atgttggccg cgtccagggt
     9181 cgggaagatc agcaggttgg cgtcctcgcg catcttggcg ttggggaaga tctgcaggcg
     9241 gtggcgggcg tcgagcgccg agtcgccgtg catctcgccc tcgacctgca gctcgggatg
     9301 gcgctcgtgc agcaggcgca tcgcggtgcg catcttcccg gcggtcggcg agtcggccga
     9361 gccgaaggac gagtgcgaca gcaacgcgat gcgcggctcg atgccgaagc gcttcatctc
     9421 ctcggcggcg agcagcgtca tctcgaccac ctgctcgggc gtggggtcgt aattgacgta
     9481 ggtgtcggcg aggaagagcg tgcgcccggg cagactgagc aggttcaccg tgtacaggtt
     9541 gtcgaccccc tcgcggcggc cgagcacgtc ctcgacgaac tcacgatgca ggcggtgcat
     9601 gccataggtg ccgcagatga ggccgtcgcc gtagccgaac ttgagcagca gcgcgccgat
     9661 cagcgtggtg cggcggcgca cctccttctt ggcgtactcg accgacaccc ccttgcgctc
     9721 catcaggccg tggtagtgct gccagagctg gttgaagcgc gggtcggagt cggggttgac
     9781 cagctcgaag tcacgctccg cggccaggcg caggccgaag cgctcgatgt tcttggccac
     9841 gacctcgggg cgaccgatga ggatcgggcg cgccagcccc tcgtccacca cctgctgcac
     9901 ggcgcgcagc accttctcgg attcgccttc cgagaagatg atccgcttcg ggttcttgtg
     9961 cgcggcggcg aacaccggct tcatgatcag gccggagtgc cagacgaagt tgttgagctg
    10021 gctgcggtag gcgttccagt cggtgatcgg gcgcgtcgcc acgcccgagg ccatgccggc
    10081 ctcggctacc gctggggcga tcttgacgat caggcgcggg tcgaaggggc gcgggatgat
    10141 gtactcgggg ccgaagccgc cgaccttctc gccgtaggcg gcggcgacga tgtcgctctg
    10201 ctccacgcgc gccagttcgg cgatggcctt caccgcggcg agctgcatct cgtcggtgat
    10261 ggtcgtcgcg ccgacgtcga gcgcgccgcg gaagatgaag gggaagcaca gcacgttgtt
    10321 gacctggttc gggtagtccg aacggccggt ggcgatgatc gcgtcgctgc gcaccgcctt
    10381 gacctcgtcg gggaggatct ccggggtcgg gttggcgagc gcgaggatca gcgggttggc
    10441 cgccatcttc gccaccatct cgcccttgag cacgccgccc gccgacagcc ccaggaacac
    10501 gtccgcgccc tcgatgacct cggcgagctt cctggcgtcg gtcttcttgg cgtagcgcgc
    10561 cttgatcggg tccatcagcg cggtgcggcc ctcatagacc acgccttcca gatcggtgac
    10621 ccagatgttc tcgaccggca cgccgagctt gaccagcagg cccaggcagg cgagcgccgc
    10681 ggcgccagcg ccggaggtca ccagcttgac cttcttgagg tccttgccct gcaggtgcag
    10741 gccgttcaac accgcggcgc cgaccacgat cgcggtgccg tgctggtcgt cgtggaagac
    10801 cgggatcttc atgcgctcgc gc
//
LOCUS       DAOTIN010000111        10710 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_7322_length_10710_cov_8.843735, whole genome shotgun sequence.
ACCESSION   DAOTIN010000111 DAOTIN010000000
VERSION     DAOTIN010000111.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 10710)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 10710)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10710
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_7322_length_10710_cov_8.843735"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(154..528)
                     /locus_tag="P5537_13540"
     CDS             complement(154..528)
                     /locus_tag="P5537_13540"
                     /inference="COORDINATES: protein motif:HMM:NF017496.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Uma2 family endonuclease"
                     /protein_id="HRV79108.1"
                     /translation="MKLFVADADAYLYPDVMVTCDERDRRAELAIEHPRLVVEVLSDS
                     TAAYDRGIKFAAYRKLADLREYLLVDVDQRRLELYRRAAGRWILLESERDGPALRLES
                     VDMTLSPAEAFEDLDEEARPEQ"
     gene            complement(525..734)
                     /locus_tag="P5537_13545"
     CDS             complement(525..734)
                     /locus_tag="P5537_13545"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79109.1"
                     /translation="MEPAQEAATLNRQAYLDWEAAQPDKNEYLVGKVFAMVGVRRGHA
                     LAALAVASRLRAHLKGSRCEPSFPT"
     gene            886..1590
                     /locus_tag="P5537_13550"
     CDS             886..1590
                     /locus_tag="P5537_13550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HRV79110.1"
                     /translation="MKTIGLLGGMSWESTVPYYRQINEAVKARLGGLHSARIVLYSVD
                     FAEIERLQRDGDWDAAGVLLAAAAQALARAGADFIVLCTNTMHKVAPAIEAATNIPLL
                     HIADPTAAAIRRAGLSRVGLLGTRFTMEQAFYRGRLVERHGIEVLVPEPGDRERVHRV
                     IYQELCLGRVEDASRAAYREVMRRLVERGAQGIVLGCTEISLLVAAEDASVPLFDTTA
                     IHAGAAVELALGLGQG"
     gene            complement(1661..2071)
                     /locus_tag="P5537_13555"
     CDS             complement(1661..2071)
                     /locus_tag="P5537_13555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4332 domain-containing protein"
                     /protein_id="HRV79111.1"
                     /translation="MANYKIEDIEGIGEVTGKKFREAGVKDTDTLLAASTTPSARAKL
                     AEATGLSSAQVLKFANMADLYRIHGIGSDYAQLLEAAGVDTVPALARRAPANLAATLA
                     QVNEEKKLTRRVPPEADVAKWVEQAKELPRVLEY"
     gene            complement(2193..2978)
                     /locus_tag="P5537_13560"
     CDS             complement(2193..2978)
                     /locus_tag="P5537_13560"
                     /EC_number="3.6.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-2,3-diacylglucosamine diphosphatase"
                     /protein_id="HRV79112.1"
                     /translation="MPEAARAALPALFISDLHLTEDEPANVAAFLAFLQGPAREAASL
                     FILGDLFEYWAGDDDLETPFNAGIAAAIRALADAGTAVFFMTGNRDLLAGADFARAIG
                     ATLLEDPARVRFGDRDDNDGADTPMLLLAHGDALCTDDLAYQAFRRQVRDPAWQAGFL
                     AQPLAARKAFIAGLRQKSEAAKAEKAMEIMDVNADAVAALLREHGYPTLVHGHTHRPD
                     IHHLNVDGRDCVRRVLPDWRGHACWLRWDGRDFTPESGDAVRI"
     gene            complement(3047..3541)
                     /locus_tag="P5537_13565"
     CDS             complement(3047..3541)
                     /locus_tag="P5537_13565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HRV79113.1"
                     /translation="MAVKLHTNHGVITLELDAEKAPVTVANFLAYVEAGHYDNTVFHR
                     VIDGFMIQGGGFEPGMKQKATGEQIKNEADNGLKNDRGTIAMARTQAPHSATAQFFIN
                     VADNAFLNHTSPDLQGWGYCVFGKVSEGMDVVDAIRKVKTGSSGFHQDVPKEDVVIER
                     AEVV"
     gene            complement(3635..4222)
                     /locus_tag="P5537_13570"
     CDS             complement(3635..4222)
                     /locus_tag="P5537_13570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HRV79114.1"
                     /translation="MKRHLLAFATAASLAFPALAANPTVELKTSQGDIVVEVFADKAP
                     KSAENFVQYVKDGFYDGTVFHRVIDGFMVQGGGFDANMNQKATRAPIENEARNGLKNE
                     RGTLAMARTSDPHSASAQFFINLVPNTFLDYPSRDGWGYAVFGKVLKGMEVVDKIAKL
                     PTANRGFHQNVPVEAIVVESARVVGTAAPAKKPSK"
     assembly_gap    4253..4352
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            4449..5834
                     /gene="cysS"
                     /locus_tag="P5537_13575"
     CDS             4449..5834
                     /gene="cysS"
                     /locus_tag="P5537_13575"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HRV79115.1"
                     /translation="MLSIYNTLSRSKEAFTPIEPGKVRMYVCGMTVYDFCHLGHARVM
                     VVFDMVARWLRASGLEVTYVRNITDIDDKIIRRAQDNGESIRQLTDRFIAAMHEDADA
                     LGVLRPDHEPRATDYVAQMQSLISRLEQKGLAYVAANRDVCYAVRKFEGYGKLSGKSL
                     DELRAGERVDVAQDKNDPLDFVLWKHAKVEEPGEVKWASPWGEGRPGWHIECSAMSSD
                     LLGDHFDIHGGGMDLQFPHHENEIAQSEGAHGHAFVNYWMHNGFVRVDDEKMSKSLGN
                     FFTIREVLQKYDPEVVRFFILRAHYRSALNYSDAHLEDARNALTRLYTALKNVPVVGE
                     PVVDWSEPFAQRLRAAMDDDFNTAEAVAVLFELANEVNRSAAPALAAQLKALGGVLGL
                     LGREPQAFLQAGAPDAGGLDADAIEARIAERAAAKKAKNFAEADRIRAELTAAGVILE
                     DGAGGTTWRRA"
     gene            5960..6385
                     /locus_tag="P5537_13580"
     CDS             5960..6385
                     /locus_tag="P5537_13580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleotide reductase subunit alpha"
                     /protein_id="HRV79116.1"
                     /translation="MIITGFQSLLDAARQQPEPQRLLLVFTRAELPEKATAEQRAKFE
                     QGEGGALVPVMYVDKKPDELQSFDELVEESRHTGQSWDMMFVGCLSGQGGREPDDDTV
                     QKALETMIMSIQGGIVAHLLAYRPNGEQVWLPDQAEGLA"
     assembly_gap    6475..6574
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(6780..7904)
                     /gene="dnaJ"
                     /locus_tag="P5537_13585"
     CDS             complement(6780..7904)
                     /gene="dnaJ"
                     /locus_tag="P5537_13585"
                     /EC_number="1.8.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HRV79117.1"
                     /translation="MSKRDYYEVLGVNRDAGDDEIKKAYRKLAMKYHPDRNPDNKEAE
                     EKFKEAKEAYEMLSDPQKKAAYDRYGHAGVDPSMGAGPGAQGFDGFADAFGDIFGDLF
                     GGGGRGGRSNVYRGADLRYNLEITLEEAARGAEKTIRIPTVEECGTCHGSGAKPGTHP
                     KPCPTCQGHGQVRVQQGFFSIQQTCPKCHGSGKIIPDPCRDCGGAGRTKKQKTLEVKI
                     PAGIDDGMRLRHAGHGEPGLNGGPPGDLYVEIHIRKHAVFERDHDDLHCEMPISITTA
                     ALGGEIEIPTLEGMARLKIPAETQSGKVFRLRGKGIKNVRSHVHGDLMCHVVVETPVN
                     LTERQRELLREFEEISSGNATRHNPKAQGWMDKVRDFFGG"
     gene            complement(8001..9935)
                     /gene="dnaK"
                     /locus_tag="P5537_13590"
     CDS             complement(8001..9935)
                     /gene="dnaK"
                     /locus_tag="P5537_13590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001737966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HRV79118.1"
                     /translation="MGKIIGIDLGTTNSCVSVMEGGKPKVIENSEGARTTPSVVAYAE
                     DGEILVGAPAKRQAVTNAKNTLFAIKRLIGRRFQEKEVQKDIDLMPFTITKADNGDAW
                     VEVRGKKIAPPQVSAEILRKMKKTAEDYLGEEVTEAVITVPAYFNDSQRQATKDAGRI
                     AGLEVKRIINEPTAAALAFGMDKKPGDSKIAVYDLGGGTFDISIIEIADLDGEHQFEV
                     LATNGDTFLGGEDFDQRIIDYIVTEFKKEQGVDLKNDVLALQRLKEAAEKAKIELSSG
                     QQTEINLPYITADASGPKHLAIKITRAKFESLVEDLIERSIEPCRIALKDAGLKVSDI
                     DDVILVGGQTRMPKVIDRVKEFFAKEPRRDVNPDEAVAVGASIQGGVLQGEVKDVLLL
                     DVTPLSLGIETLGGVMTKLIQKNTTIPTKASQVFSTADDNQSAVTIHVLQGEREMASG
                     NKSLGQFNLSDIPPAPRGMPQIEVTFDIDANGILHVSAKDKATGKENKIKIQANSGLS
                     DDEVQRMVRDAEAHAEEDKKAHELVDARNQCDALVHSTRKALTEYGDKLSDEEKAKIE
                     AAMKEAEEAIKSGDKDTIEAKSQALAMAAQKLGEQMYAQAQAEGGAQPGAGAGGQQAG
                     GKADDADVVDAEFTEVKDKK"
     gene            complement(10052..10675)
                     /gene="grpE"
                     /locus_tag="P5537_13595"
     CDS             complement(10052..10675)
                     /gene="grpE"
                     /locus_tag="P5537_13595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000774 - adenyl-nucleotide exchange
                     factor activity [Evidence IEA];
                     GO_function: GO:0051087 - chaperone binding [Evidence
                     IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HRV79119.1"
                     /translation="MQDPNQASQNPTDQPAEQAAQGGAQQPAQNGPELDLQAAAAAAD
                     TAPENGIDSMPSLEEALRQAELKAAEHHDAWLRAKAETENLRRRAQDDIAKASKFAAE
                     KFATAMLPVKDSLEAALATENQTVEKMREGVELTLKQLISAFEGAKLAEENPLGQKFD
                     PNKHQAISMVEADAEPNTVVTVLQKGYLLSERVIRPAMVMVSKGKAQ"
BASE COUNT         1423 a         3497 c         3717 g         1873 t
ORIGIN      
        1 acagaaaccg ccacgcgtcc cggacctcct gtaggagctg cggcagctgc gaatggagcg
       61 gttcggcgac cgcggcgccg gaaggagccc ggacgccgct ttcgcgcctg ccggcgctcc
      121 tacatggagc gcagcgcctc cgcgcaaacc acgtcactgc tccggtcgag cctcctcgtc
      181 caggtcctcg aacgcctctg ccggtgaaag cgtcatgtcc acgctctcca ggcgcagcgc
      241 cggcccgtcc cgctcgctct cgagcaggat ccagcgcccg gccgcgcgcc ggtacaactc
      301 caggcggcgc tgatcgacgt caaccagcag gtattcgcgc agatcggcca gcttgcgata
      361 agcggcgaac ttgatgccgc gatcgtaggc ggcggtggag tccgacagca cctccaccac
      421 caggcgcgga tgctcgatcg ccagctcggc acggcggtcg cgctcgtcgc aggtgaccat
      481 cacgtccggg tagaggtagg cgtccgcatc ggcgacgaaa agtttcatgt cggaaacgaa
      541 ggttcgcagc gtgagccctt gaggtgcgcg cgaagtcgac tcgcgactgc gagcgctgcc
      601 agcgcatgcc cgcgcctgac cccaaccatc gcgaacacct tgccgaccag atactcgttc
      661 ttgtccggct gcgcggcctc ccagtcgagg taggcctgcc gattcagcgt cgcggcttcc
      721 tgtgccggct ccattgcgaa gctccggtcg atgtcccgcc attgtgggcg aggagggcga
      781 cgggttcaac gctgcacccc agcagcgttg cagttcgagg cccgcggcgt cgcgcccgcc
      841 cccgtggcat cctgtgcact cctcatcctc ccggacccgc cccccatgaa gaccatcggc
      901 ctcctcggcg gcatgagctg ggaatccacc gtgccttact accgccagat caacgaagcg
      961 gtgaaggccc gcctcggcgg cctgcactcg gccaggatcg tgctgtacag cgtcgacttc
     1021 gccgagatcg agcgcctgca gcgcgacggc gactgggacg ccgccggcgt gttgctcgcc
     1081 gcggccgcgc aggcgctcgc gcgcgccgga gccgacttca tcgtgctgtg caccaacacc
     1141 atgcacaagg tggcccccgc catcgaggcc gcgacgaaca tcccgctgct ccacatcgcc
     1201 gaccccaccg cagccgccat ccgccgcgcc ggcctgtccc gcgtcggcct gctcggcacg
     1261 cgcttcacca tggagcaggc cttctaccgc ggccgtctcg tggagcgcca cggtatcgag
     1321 gtgctcgtcc ccgagccggg cgaccgcgaa cgcgtgcatc gggtgatcta ccaggagctc
     1381 tgcctcggcc gcgtcgaaga cgcctcgcgc gccgcctacc gcgaggtgat gcgccgcctg
     1441 gtcgagcgcg gcgcgcaagg catcgtcctc ggctgcaccg agatctcgct gctggtggcg
     1501 gcggaggacg cgagtgtgcc gctgttcgac accacggcga tccatgcggg ggcggcggtg
     1561 gaactggcgt tggggcttgg gcagggatag gggagctgca ggggagggat agggggcagt
     1621 ggcggaccgt cgccgccgat gccgccccct tgaactccga tcagtactcc agcaccctcg
     1681 gcaactcctt cgcctgctcg acccacttgg cgacgtcggc ctcgggcggg acgcggcggg
     1741 tgagcttttt ctcctcgttg acctgggcca gcgtcgcggc caggttggcc ggggcgcggc
     1801 gggcgagggc ggggacggtg tccacgccgg cggcctcgag gagctgggcg tagtcggagc
     1861 cgataccgtg gatgcggtag aggtcggcca tgttggcgaa cttcagcacc tgggcgctgg
     1921 agaggccggt ggcttcggcg agcttggcgc gcgccgaggg cgtggtgctc gcggcgagca
     1981 gcgtgtcggt gtccttgacg ccggcttcgc ggaacttctt gccggtgact tcgccgatgc
     2041 cttcgatgtc ttcgatcttg taattcgcca tcctgcagcc tcctgtgggc gttgaacgag
     2101 tggcccggtc ccggcgccgg ggttgctccg tggagacccc cggcgccggt cctgacgatt
     2161 cgatcttaag cccacagcgc tgccgtggtg cgttaaatcc tgacggcatc gcccgattcg
     2221 ggcgtgaagt cgcggccgtc ccagcgcagc cagcaggcgt ggccgcgcca gtcgggcagc
     2281 acgcggcgca cgcagtcgcg gccgtccaca ttgaggtggt ggatgtcggg acggtgggtg
     2341 tggccgtgca ccagcgtcgg atagccgtgc tcgcgcagca gggcggcgac cgcgtcggcg
     2401 ttgacgtcca tgatctccat ggccttctcg gccttggcgg cctcgctctt ctggcgcagg
     2461 ccggcgatga aggccttgcg cgcggccagc ggctgggcga ggaagccggc ctgccaggcg
     2521 gggtcgcgca cctggcggcg gaaggcctgg taggcgaggt cgtcggtgca cagcgcgtcg
     2581 ccgtgggcga gcagcagcat cggggtgtcg gcgccgtcgt tgtcgtcgcg atcgccgaag
     2641 cgcacgcgcg ccgggtcctc cagcagggtg gcgccgatgg cgcgggcgaa gtccgcgccg
     2701 gcgagcaggt cgcggttgcc ggtcatgaag aagaccgcgg tgccggcgtc ggcgagcgcg
     2761 cggatcgcgg cggcgatgcc ggcattgaag ggggtctcga ggtcgtcgtc gccggcccag
     2821 tattcgaaca ggtcgccgag gatgaagagg cttgccgcct cgcgcgccgg gccttgcagg
     2881 aaggcgagga aggcggcgac gttggcgggc tcgtcctcgg tcaggtggag gtcggaaatg
     2941 aataatgccg gaagcgccgc gcgggcggct tccggcatcg tgacggcggc ttcgcccggc
     3001 cgggccgggg cggaagccgc ttgcgaaggg tcgcgcgcgg gcacgatcag acgacttcgg
     3061 cgcgctcgat gaccacgtct tccttgggca cgtcctggtg gaagccgctg gagccggtct
     3121 tgaccttgcg gatggcatcg accacgtcca tgccctcgct gaccttgccg aacacacagt
     3181 agccccagcc ttgcaggtcg ggcgaggtgt ggttgaggaa ggcgttgtcg gcgacgttga
     3241 tgaagaactg cgcggtggcc gagtgcgggg cctgggtgcg cgccatggcg atggtgccgc
     3301 ggtcgttctt gaggccgttg tcggcttcgt tcttgatctg ctcgccggtg gccttctgct
     3361 tcatgccggg ctcgaagccg ccgccctgga tcatgaagcc gtcgatgacg cggtggaaga
     3421 cggtgttgtc gtagtggccg gcctcgacgt aggcgaggaa gttggcgacg gtgaccgggg
     3481 ccttctcggc gtcgagttcg agggtgatga cgccgtggtt ggtgtgcagc ttgactgcca
     3541 tgcggattct cctggaatgg atctggcgtg ggctcggcgg ggtggccgcc gggcggtggg
     3601 gttgggtctt gcttcgaggg cctgcttcgc gggcttactt cgagggcttt ttcgccggcg
     3661 cggcggtgcc gaccacgcgg gcgctctcga cgacgatggc ctcgaccggc acgttctggt
     3721 ggaagccgcg gttggcggtg ggcagcttgg cgatcttgtc gaccacctcc atgcccttca
     3781 ggaccttgcc gaacaccgcg tagccccagc cgtcgcgcga ggggtagtcg aggaaggtgt
     3841 tggggacgag gttgatgaag aactgcgcgc tcgccgagtg cgggtcggag gtgcgcgcca
     3901 tcgccagcgt gccgcgctcg ttcttgaggc cgttcctggc ctcgttctcg atcggggcgc
     3961 gggtggcctt ctggttcatg ttcgcgtcga agccgccgcc ctgcaccatg aagccgtcga
     4021 tcacgcggtg gaacacggtg ccgtcgtaga agccgtcctt cacgtactgc acgaagtttt
     4081 cggcggactt gggcgccttg tcggcgaaga cctcgacgac gatgtcgccc tggctggtct
     4141 tgagctcgac cgtcgggttg gcggcgagcg ccgggaaggc gaggctggcc gcggtggcga
     4201 aggcaagcag gtgtcgtttc atgggggctc ctgggatggg gcgggagggt ggnnnnnnnn
     4261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nngagcgccg gattctagca acaagccccc
     4381 cccctcacaa tcgagccgcc gcccgcgtcc cgccggtggc cggtctccag ccacgacccg
     4441 tccgcccgat gctctccatc tacaacaccc tgtcgcgcag caaggaagcc ttcacgccca
     4501 tcgaacccgg caaggtccgc atgtacgtgt gcggcatgac ggtgtacgac ttctgccacc
     4561 tcggccatgc gcgcgtgatg gtggtgttcg acatggtcgc gcgctggctg cgcgcgagcg
     4621 ggctcgaagt gacctacgtg cgcaacatca ccgacatcga cgacaagatc atccgccgcg
     4681 cgcaggacaa cggcgagagc atccgccagc tcaccgaccg cttcatcgcc gcgatgcacg
     4741 aggacgccga cgcgctcggc gtgctgcgcc ccgaccacga gccgcgcgcc accgactacg
     4801 tggcgcagat gcagtcgctg atctcgcgtc tcgagcaaaa gggcctggcc tacgtcgccg
     4861 ccaaccgcga cgtgtgctac gcggtgcgca agttcgaggg ctacggcaag ctttcgggca
     4921 agtcgctcga cgagctgcgc gccggcgagc gcgtcgacgt ggcgcaggac aagaacgacc
     4981 cgctcgactt cgtgctgtgg aagcacgcca aggtcgagga gccgggcgag gtcaagtggg
     5041 cgtcgccgtg gggcgagggc cgcccgggct ggcacatcga gtgctcggcg atgagctcgg
     5101 acctgctcgg cgaccacttc gacatccacg gcggcggcat ggacctgcag ttcccccacc
     5161 acgagaacga gatcgcccag tccgagggcg cgcacggcca cgccttcgtc aattactgga
     5221 tgcacaacgg cttcgtgcgc gtcgacgacg agaagatgtc gaagtcgctg ggcaacttct
     5281 tcaccatccg cgaggtgctg cagaagtacg accccgaggt ggtgcgcttc ttcatcctgc
     5341 gcgcgcacta ccgcagcgcg ctcaactact ccgacgcgca tctcgaagat gcccgcaacg
     5401 cgctcacccg gctgtacacc gcgctgaaga acgtgccggt ggtcggcgaa ccggtggtcg
     5461 actggagcga gcccttcgcg cagcgcctgc gcgcggcgat ggacgacgac ttcaacaccg
     5521 ccgaggccgt ggccgtgctg ttcgagctcg ccaacgaggt caaccgcagc gccgcgccgg
     5581 cgctcgccgc gcagttgaag gcgctcggcg gcgtgctcgg cctgctcggt cgcgagccgc
     5641 aggcctttct gcaggcgggc gcgccggacg ccggcgggct cgacgccgac gcgatcgagg
     5701 cccgcatcgc cgaacgcgcc gccgccaaga aggcgaagaa cttcgccgag gccgaccgca
     5761 tccgcgccga gctcaccgcc gccggcgtga tcctggagga cggcgccggc ggcaccacct
     5821 ggcgccgcgc ctgagcgccc tacggccggc gtgcgggccg cagcggtcgg cacacggccg
     5881 cgccgccctt gcgcctcgcg gtgccctgcc cgcccgaacc gaacccaacc gacccgaacc
     5941 tgcacaagga accccgcaca tgatcatcac cggcttccag agcctgctcg acgccgcccg
     6001 ccagcagccc gaaccgcagc gcctgctgct cgtcttcacc cgcgccgagc tccccgagaa
     6061 ggctaccgcc gagcagcgcg ccaagttcga gcagggcgag ggcggggcgc tggtgccggt
     6121 gatgtacgtg gacaagaagc ccgacgagct gcagagcttc gacgagctgg tcgaggagtc
     6181 gcgccacacc gggcagagct gggacatgat gttcgtcggc tgcctgagcg ggcagggtgg
     6241 gcgcgagccg gacgacgaca cggtgcagaa ggcgctcgag accatgatca tgtcgatcca
     6301 gggcggcatc gtcgcccacc tgctggccta ccgccccaac ggcgagcagg tctggctgcc
     6361 cgaccaggcc gaaggcctcg cctgagggat cggggtgcgc gtcgtctccg gattgcccca
     6421 ttcgcggctg ccgccgctcc tacaaggagc gccgcgacgg tttctgtagg agcgnnnnnn
     6481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6541 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnattcgc ggctgccgcc gctcctacaa
     6601 ggagcgccgc gacggtttct gtaggagcgc cggaaggcgc gaacgcggcg gtcgggatcg
     6661 ggtcgcgcgt cgtttccgga ttgccccatt cgcggctgcc gccgctccta caaggagcgc
     6721 cgcgacggtt tctgtaggag cggcggcagc cgcgaacgct tgccgctgcg atccccgtct
     6781 cagccgccga agaagtcccg caccttgtcc atccacccct gcgccttggg gttgtggcga
     6841 gtggcgttgc cgctggagat ctcctcgaac tcgcgcagca gctcgcgctg acgctcggtg
     6901 aggttcaccg gggtctcgac caccacgtgg cacatcaggt cgccgtgcac atggctgcgc
     6961 acgttcttga tgcccttgcc gcgcagccgg aagaccttac cgctctgggt ctcggcgggg
     7021 atcttgagcc gcgccatgcc ttcgagcgtg gggatctcga tctcgccacc gagcgccgcg
     7081 gtggtgatgc tgatcggcat ctcgcagtgc aggtcgtcgt ggtcgcgctc gaacaccgcg
     7141 tgcttgcgga tgtggatctc gacgtagagg tcgcccggcg ggccgccgtt gaggccgggc
     7201 tcgccgtgac cggcgtggcg caggcgcatg ccgtcgtcga tgccggcggg gatcttgacc
     7261 tcgagtgtct tttgcttctt ggtgcggccg gcgccgccgc agtcgcggca ggggtcgggg
     7321 atgatcttgc cgctgccgtg gcacttcggg caggtctgct ggatcgagaa gaagccttgc
     7381 tgcacgcgca cctggccgtg gccctggcag gtggggcagg gcttggggtg ggtgccgggc
     7441 ttggcgccgc tgccgtggca ggtgccgcac tcctcgacgg tggggatgcg gatcgtcttc
     7501 tcggcgccgc gcgcggcctc ttccagggtg atctcgaggt tgtagcgcag atcggcgccg
     7561 cgatagacgt tcgagcgccc gccgcgcccg ccgccgccga agaggtcgcc gaagatgtcg
     7621 ccgaaggcat cggcgaagcc gtcgaaaccc tgtgcgccgg ggccggcacc catggacgga
     7681 tcgacgccgg cgtggccgta gcggtcgtag gcggccttct tctgcgggtc ggagagcatc
     7741 tcgtaggcct ccttggcctc cttgaacttc tcttccgctt ccttgttgtc cggattgcgg
     7801 tccgggtggt acttcatggc cagcttgcgg taggccttct tgatctcgtc gtcgcccgcg
     7861 tcgcgattga cgccgaggac ttcgtagtaa tcccttttgg acatggtgct tcgctcagtc
     7921 tggtctcaag caaaggccga gccggcaccg gagcagggct ccggcggggc tcggccgcga
     7981 aggattcgcc agagtgacga ttacttcttg tccttcactt cggtgaactc ggcatccacc
     8041 acgtcggcgt cgtcggcctt gccgccggcc tgctggccgc ccgcgccggc acccggctgg
     8101 gcgccgcctt cggcctgggc ctgggcgtac atctgctcgc cgagcttctg cgcggccatc
     8161 gccagcgcct ggctcttggc ttcgatcgtg tccttgtcgc cgctcttgat ggcctcctcg
     8221 gcctccttca tcgcggcctc gatcttggcc ttctcctcat ccgacagctt gtcgccgtac
     8281 tcggtcagcg ccttgcgggt cgagtgcacc agggcgtcgc actggttgcg cgcgtcgacc
     8341 agctcgtggg ccttcttgtc ttcctcggcg tgcgcctcgg cgtcgcgcac catgcgctgg
     8401 acctcgtcgt ccgacaggcc ggagttggcc tggatcttga tcttgttctc cttgccggtg
     8461 gccttgtcct tggccgacac gtgcaggatg ccgttggcgt cgatgtcgaa ggtgacctcg
     8521 atctgcggca tgccgcgcgg cgccggcggg atgtccgaca ggttgaactg gcccaggctc
     8581 ttgttgcccg aggccatctc gcgctcgccc tgcagcacgt ggatggtcac ggccgactgg
     8641 ttgtcgtcgg cggtcgagaa cacctgcgag gccttggtcg ggatcgtggt gttcttctgg
     8701 atcagcttgg tcatcacgcc gccgagggtc tcgatgccga gcgacagcgg ggtgacgtcg
     8761 agcagcagca cgtccttgac ctcgccctgc agcacgccgc cctggatgga ggcgccgacg
     8821 gcgacggcct cgtccgggtt cacgtcacgg cgcggctcct tggcgaagaa ctccttcacg
     8881 cggtcgatga ccttgggcat gcgggtctgg ccgccgacca ggatcacgtc gtcgatgtcc
     8941 gaaaccttga ggccggcgtc cttgagcgcg atgcggcagg gctcgatcga gcgctcgatc
     9001 aggtcctcga ccagcgactc gaacttggcg cgggtgatct tgatcgccaa gtgcttcggg
     9061 cccgaggcgt cggcggtgat gtagggcagg ttgatctcgg tctgctggcc cgaggacagc
     9121 tcgatcttgg ccttctcggc ggcttccttc aggcgctgca gcgcgagcac gtcgttcttg
     9181 agatcgacgc cctgttcctt tttgaactcg gtgacgatgt agtcgatgat gcgctggtcg
     9241 aagtcctcgc cgcccaggaa ggtgtcgccg ttggtggcca gcacttcgaa ctggtgctcg
     9301 ccgtcgaggt cggcgatctc gatgatcgag atgtcgaagg tgccgccgcc gaggtcatac
     9361 acggcgatct tggagtcgcc cggcttcttg tccatgccga aggcgagcgc ggccgcggtg
     9421 ggctcgttga tgatgcgctt gacctcgagg ccggcgatgc ggccggcgtc cttggtggcc
     9481 tggcgctggc tgtcgttgaa gtaggccggc acggtgatca ccgcctcggt cacttcctcg
     9541 ccgaggtagt cctcggcggt cttcttcatc ttgcgcagga tctcggcgga gacctgcggc
     9601 ggggcgatct tcttgccgcg cacttccacc caggcgtcgc cgttgtcggc cttggtgatg
     9661 gtgaagggca tcaggtcgat gtccttctgc acttccttct cctggaagcg acggccgatc
     9721 aggcgcttga tcgcgaacag ggtgttcttg gcgttggtga cggcctgacg cttggccggc
     9781 gcgccgacca ggatctcgcc gtcctcggcg taggcgacca ccgacggggt ggtgcgcgcg
     9841 ccttcggagt tttcgatgac cttcggcttg ccgccttcca tcacggagac gcagctgttg
     9901 gtggtgccga ggtcgatacc gatgatcttg cccatgagag ttcctttttc gtctggattc
     9961 gggtggcgcg gcctgcggcg cgccgttctg gttcgaatat ggggcaggcg gcgacgcttt
    10021 caagcgcgcc gcgcgaattt gcctgcgctt cttactgggc cttgcccttg gagaccatca
    10081 ccatcgccgg gcggatgacg cgctcgctga gcaggtagcc cttctgcagc acggtgacga
    10141 cggtgttggg ctcggcgtcg gcctcgacca tgctgattgc ctggtgcttg ttggggtcga
    10201 acttctgccc gagcgggttc tcctcggcaa gcttcgcgcc ctcgaaggcg gagatcagct
    10261 gcttgagcgt caattcgacg ccctcgcgca tcttctccac ggtctggttc tcggtggcga
    10321 gcgcggcttc gaggctgtcc ttcaccggca gcatcgcggt ggcgaacttc tcggcggcga
    10381 atttcgacgc cttggcgatg tcgtcctgcg cgcgccggcg caggttctcg gtctcggcct
    10441 tggcgcgcag ccaggcgtcg tggtgctcgg cggccttcag ctcggcctgg cgcagcgcct
    10501 cctcgaggct cggcatgctg tcgatgccgt tctccggcgc ggtatcggcc gccgcggcgg
    10561 cggcctggag gtcgagctcc gggccgttct gcgcgggctg ctgcgcgccg ccctgcgcgg
    10621 cctgctccgc cggctggtcg gtagggttct ggctggcctg gttcgggtcc tgcatgtcgg
    10681 ttggctccgt gttggaatgc gaaacagccg
//
LOCUS       DAOTIN010000112        10696 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_7336_length_10696_cov_8.328822, whole genome shotgun sequence.
ACCESSION   DAOTIN010000112 DAOTIN010000000
VERSION     DAOTIN010000112.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 10696)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 10696)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10696
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_7336_length_10696_cov_8.328822"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(87..620)
                     /gene="thpR"
                     /locus_tag="P5537_13600"
     CDS             complement(87..620)
                     /gene="thpR"
                     /locus_tag="P5537_13600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002928962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008664 - 2'-5'-RNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2',3'-cyclic phosphodiesterase"
                     /protein_id="HRV79120.1"
                     /translation="MEPRLRLFFALWPDSATSAALHARARALHTECGGRAMRRDTIHL
                     TLAFLGDTPAREVQRLRALAAQVDGESFALALDHVGSWKRNRVLWTGPSIVPPALAAL
                     AQDLEARLRAAGFALEERAFSPHVTLVRNARAAPAEAPPAPLRWSVASFVLVASERSA
                     AGAHYRVIGRWPLQQRV"
     gene            complement(805..1308)
                     /gene="ispF"
                     /locus_tag="P5537_13605"
     CDS             complement(805..1308)
                     /gene="ispF"
                     /locus_tag="P5537_13605"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004374518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008685 - 2-C-methyl-D-erythritol
                     2,4-cyclodiphosphate synthase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HRV79121.1"
                     /translation="MSTPFIPFRIGQGFDVHALVPGRPLIVGGVTIPFERGLLGHSDA
                     DVLLHAVTDALLGAAGLGDIGRLFPDTDPAHAGADSRVLLREAFARVRAAGWEVVNID
                     ATLICKAPRILPHAPAMVANLAADLDMDAAAINIKGKTTEKLGFTGRGEGIAAQVVAL
                     ITRAGQG"
     gene            complement(1305..2015)
                     /gene="ispD"
                     /locus_tag="P5537_13610"
     CDS             complement(1305..2015)
                     /gene="ispD"
                     /locus_tag="P5537_13610"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HRV79122.1"
                     /translation="MQTTHPRHFAIVPAAGSGSRMAAARPKQYLSLLGRPLIHHALAV
                     LCAAPSIDAVFVVLSVDDTEWATHDWSALGPKLRPLFCGGATRADSVLGGLRAIAGDA
                     AAGDWVLVHDAARPCLAPWHVDKLVRELAHDEVGGLLAVPVADTLKRADEHRHVCETV
                     PRDSLWQAQTPQMFRYAMLRRALEGAREVTDEASAIEAAGLRPRLVQGDATNLKVTYP
                     LDLHLAEWILKNREGHNA"
     gene            2145..2969
                     /gene="amrB"
                     /locus_tag="P5537_13615"
     CDS             2145..2969
                     /gene="amrB"
                     /locus_tag="P5537_13615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AmmeMemoRadiSam system protein B"
                     /protein_id="HRV79123.1"
                     /translation="MALASIRPAAVAGQFYPRDERVLRTQLAEMLSTAVAFESAPAPK
                     AIIVPHAGYMYSGPVAASAYALLAPLRERIRRVVLLGPTHRVAVRGFSLPAAQRFATP
                     LGEVPLARDDWQALQARDDVLVDDRPHAEEHCLEVQLPFLQVCLERFEIVPILVGDAS
                     PEATAGLIESLWGGPETLILISSDLSHYLSYRAAQWSDRAAVDQVLELRAGLNHEQAC
                     GATPINGLLLAARKHHLQAHLLDLRNSGDTAGDRSRVVGYTSIAFCEAEPPSHARH"
     gene            2956..3522
                     /gene="amrA"
                     /locus_tag="P5537_13620"
     CDS             2956..3522
                     /gene="amrA"
                     /locus_tag="P5537_13620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AmmeMemoRadiSam system protein A"
                     /protein_id="HRV79124.1"
                     /translation="MPDTDFGTTLLALARAAIAHRLGRGPAPVVPDDPRLREKGATFI
                     TLARDGELRGCIGSLRRSRELGEDVIHNALAAAFEDSRFEPLAAEELDAVTIEVSILS
                     EPEFLDFFGEEELIAQLRPGEDGLIIFSGCRSATFLPQVWEQLPEPRQFLAALKHKAG
                     LPTNREVVELMAARYHVEKWKETEREPS"
     gene            3519..4658
                     /gene="amrS"
                     /locus_tag="P5537_13625"
     CDS             3519..4658
                     /gene="amrS"
                     /locus_tag="P5537_13625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AmmeMemoRadiSam system radical SAM enzyme"
                     /protein_id="HRV79125.1"
                     /translation="MSTKPEPAADAGRTEVGSRHPARYWHRIDDGRYQCDLCPRLCKL
                     HPGQRGACFVRMREGDDMLLTTYGRSSGFCIDPIEKKPLNHFYPGSKVFSFGTAGCNL
                     ACKFCQNWDISKSRDLDTLMDEASPAEIADTALHWGCHSVAFTYNDPVIFAEYAMDVA
                     DACHARGLKTVAVTAGYISECARRDFFSRMDAANVDLKGFTDDFYVKLCGAHLQPVLD
                     TLVWLRHETDVWVELTTLLIPGHNDTDSEVAALAKWVREELGAEVPLHFSAFHPDFKM
                     DDLPPTPPATLTRARRIALDAGLKHVYTGNVHDTEGDTTHCASCGEALIVRDWYEIRR
                     YALGADGRCPHCGSVLAGRFGAVGAAVGEAFGARRIPVAIHRHGT"
     gene            4677..5333
                     /locus_tag="P5537_13630"
     CDS             4677..5333
                     /locus_tag="P5537_13630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HRV79126.1"
                     /translation="MKLRNTLISIPAQGAWLDGLLAHAPDVRGLAVLPQSSGHPALDT
                     GPRPLELALQSRGFATMRLDLLTRQEALRDPDASFNITRLTERILAAVEWIAHQPPLA
                     GLQLGLVAHDTGCAAAIRAAVKAPETFAAIACVDGRADLAGAEPLRHLRCPVRFIVTP
                     GVPESAILEKAFSLLGGPRHWLALPDAGDARQQELLQARAVTSWLEQHLAVVERVRVE
                     "
     gene            5363..5980
                     /locus_tag="P5537_13635"
     CDS             5363..5980
                     /locus_tag="P5537_13635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metalloprotease CJM1_0395 family
                     protein"
                     /protein_id="HRV79127.1"
                     /translation="MSVSSLGGAYAAWRQTTTMHDARAADAAAAPAMAQGGGDTQATP
                     AGLADALSEAEQRQVAELAKRDREVRAHEMAHVAAGAGLVTRGASYTYQTGPDGQRYA
                     IGGEVGIDTSPGRTPEETLAKAERIRAAALAPAEPSGQDRQVAAQAARMANDARLEIA
                     RREFAQGDTGAEATRDGAVDRGMRAAQAYSEGLAPRQAPTLSASA"
     gene            6132..9656
                     /gene="mfd"
                     /locus_tag="P5537_13640"
     CDS             6132..9656
                     /gene="mfd"
                     /locus_tag="P5537_13640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003690 - double-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HRV79128.1"
                     /translation="MSFSLDALLSRLATVKLPKPGGRLELDALAGSADALAIAQLASR
                     GRMLVVITANPLDAQRLQDEIAWVAPGLRAHLLPDWETLPYDSFSPHQDLISERLSTL
                     YAISRGETDLVLVPASTALYRMAPPSYLAAYTFFLKQGEKLDVEQFKAQMALAGYAHV
                     TQVVSPGEFSVRGGLVDLFPMGSPLPFRIDLFDDEVESIKTFDPDTQRTVYPTKEIRL
                     LPAREFPLDDKGRTRFRSRFRETFEGDPTRASIYKDVSNGIAPAGIEYYLPLFFDDTA
                     TLLDYLPAETAVLLHRDVPAAIAEFWKDTRSRHDLLKGDRTRPVLAPEQLFLSDEAFF
                     VALKNLPRLSIGAEASAEAADALALPPPEVAVERKATDPLHKLKAFLDGFDGRVLLLS
                     DSPGRRETMAEFFAEYGVKPEASADFGAFLDGDARLALGVAPLARGFVLPAARLAVLT
                     ETELYAATARSRVRRDARKAATMEGWLRDLSELKVGDPVVHVSHGIGRYLGLIHMNLG
                     EGDTEFLHLEYNGGDKLYVPVSQLHVITRYAGADPEAVDLHRLGSGQWEKAKKKAAMQ
                     VRDTAAELLALYAQRAARPGHRFDFKQHDLEAFAEGFGFETTPDQQSAIDAVVGDMKS
                     GRPMDRLVCGDVGFGKTEVALRAAFIAVADGKQVVVLCPTTLLAEQHYQTFADRFADW
                     PIKLAELSRFKSAKEQAEALQQLTEGKVDIIIGTHRLLQKDVVFKRLGLVIIDEEHRF
                     GVRQKEALKQLRSEVDILTLTATPIPRTLGLAMEGLREFSVIATPPQKRLSIKTFVQP
                     SSRGVIREAVLREFKRGGQVYFLHNEVDTIDNIKDDLKELLPEARIVVGHGQLPEREL
                     ERVMRDFTQQRANLLLCTTIIETGINIPTANTIIINRADRFGLAQLHQLRGRVGRSHH
                     QAYAYLLTMPGAKPTAQAQKRLEAIAMMEDLGSGFYLAMHDLEIRGAGEVLGENQSGE
                     IQQVGFSLYTEMLKRAVKDLQAGKEPDLSQPLEVVSEINLHTPALLPTDYCPDVQERL
                     TLYKRLANCELEEDLRFLQEELIDRFGELPPQTAALIETHRLRMLVKDYGVHKLDASD
                     AQISVQFAKDAPIDPVKVIFLIQKDRSTKMAGPEKLVRRASLPNLKERVKAVKDLLDA
                     VRADAPKADGVKADGEKPGGAKAKALKT"
     gene            9673..10638
                     /gene="corA"
                     /locus_tag="P5537_13645"
     CDS             9673..10638
                     /gene="corA"
                     /locus_tag="P5537_13645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015087 - cobalt ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006824 - cobalt ion transport [Evidence
                     IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium/cobalt transporter CorA"
                     /protein_id="HRV79129.1"
                     /translation="MLINCTAYQHGRKHADIPVEDISEYVQQPDTFVWVALKDASAEE
                     LAVMKEEFGLHELAIEDANHRHQRPKVEEYDDELFVVMHLVEEREGKLEVGEVHVFVG
                     ANYILSVRNNHARDFLGVRARCEREPRMLAKGPGYVLYALMDAVVDGYFPLIDKLETE
                     VEALEERIFTKGAGNSNMRRLYRLKRKVTLLKHAVLPLMEAAGKLHSGRVPEVCAKSR
                     HYFRDVYDHLARIDASLDSVRETIGTAIQVNISLVTIDQTEVSKRLAAWAGIFAVATA
                     FAGIWGMNFSHMPELEWEYGYFAGLGVIASASAFLWWRFRKARWL"
BASE COUNT         1666 a         3996 c         3506 g         1528 t
ORIGIN      
        1 ttcgcgcctg ccggcgctcc tacattggac ggaaccgcgc cggcttctgc aggagcggcg
       61 gcggccgcga atgcggcgaa tggtcatcac acgcgctgct gcagcggcca gcgcccgatc
      121 acccggtagt gcgcaccggc ggcgctgcgc tcggaagcca ccaggacaaa gctggccaca
      181 ctccaccgca agggtgccgg cggtgcctcg gcgggcgctg cgcgggcgtt gcgcaccagc
      241 gtgacatgcg gtgaaaaggc acgctcctcg agcgcgaagc cggccgcgcg cagccgggcc
      301 tccaggtcct gcgcgagcgc ggccagcgcg ggcggtacga tggacggtcc ggtccacagg
      361 acgcggttgc gcttccagct cccgacgtgg tcgagcgcga gcgcgaagct ttccccgtcg
      421 acctgcgcag ccagcgcccg caggcgctgc acctcccgcg cgggcgtgtc gccgaggaag
      481 gccagggtca ggtgaatggt gtcgcggcgc atcgcgcgac cgccgcactc cgtgtgcagc
      541 gcccgtgcgc gtgcatgcag cgcggcgctg gtggccgaat ccggccacaa cgcaaagaag
      601 agccgtaacc gcggctccat tcccgcgctt ccacgctcac ccgagtccgt accctcgccc
      661 acgccatcct tcgctgcggc cggtttagaa cttccccctg tgcccaggcc tgcgtaagcg
      721 cccgtgcctg cgttcatgct cgcgcccgcc tcagccatgc ctcgacttcc cgtccgcacc
      781 ggccatcgcc atgacgcgcc ttgctcagcc ctgccccgca cgtgtgatca aagcgaccac
      841 ctgcgcggcg atgccctccc ctcgcccggt gaaaccgagc ttctcggtgg tcttgccctt
      901 gatgttgatc gccgccgcgt ccatgtcgag gtcggcggcg aggttggcca ccatggccgg
      961 tgcgtgcggc aggatgcgcg gcgccttgca gatcagcgtg gcatcgatat tgaccacctc
     1021 ccagcccgcg gcgcgcacgc gcgcgaaggc ctcgcgcagc agcacgcggc tgtcggcgcc
     1081 ggcgtgggcc gggtcggtgt cggggaagag ccggccgatg tcgcccagcc cggcggcgcc
     1141 gagcagcgcg tcggtgaccg cgtgcagcag cacatcggca tcggagtgcc cgagcaggcc
     1201 gcgttcgaag gggatggtta cgccgccgac gatcagcggc cggccgggga cgagggcgtg
     1261 aacgtcgaag ccctggccga tgcgaaaggg gatgaaggga gtgctcatgc gttgtgaccc
     1321 tcgcggttct tgaggatcca ctcggccagg tgcaggtcga gcggataggt gaccttcagg
     1381 ttggtggcgt cgccctgcac cagccgcggc cgcagcccgg cggcctcgat cgcgctcgcc
     1441 tcgtcggtga cctcgcgcgc gccctccagg gctcggcgca gcatggcgta acggaacatc
     1501 tgcggcgtct gcgcctgcca caggctgtcg cgcggcacgg tctcgcagac gtggcggtgc
     1561 tcgtcggcgc gcttgagagt gtcggccacc ggcaccgcca gcagcccgcc gacctcgtcg
     1621 tgagcgagct cgcgtaccag cttgtcaaca tgccacggcg ccaggcaggg acgcgcggcg
     1681 tcgtgcacca gcacccagtc gcccgccgcc gcatcgccgg cgatcgcgcg caggccgccg
     1741 agcacgctgt cggcccgcgt ggcgccaccg cagaagagcg ggcgcagctt ggggccgagc
     1801 gcgctccagt cgtgcgtggc ccactccgtg tcatccaccg agagcacgac gaagaccgcg
     1861 tcgatcgagg gcgcggcaca cagcaccgcg agggcgtggt ggatcagggg gcggccgagc
     1921 agcgacagat actgcttggg gcgggcggcg gccatgcgcg agccgctgcc ggcggcgggc
     1981 acgatggcga agtggcgtgg gtgggtggtc tgcatggcgc gcattctagc cgcgccgccc
     2041 atggcgcggg cttgtgcaag cgcgggtttc gaagcgggac gatcccggcc gggctgccta
     2101 taatgggaaa tgttccaacc atgacatccc cgcaggattg caccatggca ctcgcttcga
     2161 tccgcccggc agccgtggcc gggcagttct atccccgcga cgagcgcgtg ctgcgcaccc
     2221 agctcgccga gatgctctcg accgccgtcg ccttcgagtc ggcgccggcc ccgaaggcga
     2281 tcatcgtgcc gcacgccggc tacatgtatt ccgggccggt ggcggcgagc gcctatgcgc
     2341 tgctcgcgcc attgcgcgag cgcatccgcc gcgtcgttct gctcggcccc acgcatcgcg
     2401 tggcggtgcg cggcttttcg ctgccggcgg cgcagcgctt cgccacgccg ctcggcgagg
     2461 tgccgctcgc gcgcgacgac tggcaggccc tgcaggcgcg cgacgacgtc ctggtcgatg
     2521 accgcccgca tgccgaggag cactgcctcg aggtgcagct gcccttcctg caggtctgcc
     2581 tcgagcgctt cgagatcgtg ccgatcctgg tcggcgatgc ctcgcccgaa gccaccgccg
     2641 gcctgatcga gagcctgtgg ggcggacccg agaccctgat cctgatcagc tcggacctct
     2701 cgcactacct gagctatcgc gcggcacagt ggtccgatcg cgcggcggtc gaccaggtgc
     2761 tcgagttgcg cgccggcctc aaccacgagc aggcctgtgg cgccaccccg atcaacgggc
     2821 tgctgctcgc cgcccgcaag catcacctgc aggcccacct gctggacctg cgcaactccg
     2881 gcgacacggc gggcgaccgc tcgcgcgtcg tcggctacac cagcatcgcc ttttgtgaag
     2941 cggaaccccc aagccatgcc cgacactgat ttcggtacca ccctgctcgc gctcgcccgc
     3001 gccgcgatcg cccaccgcct cggccgcggg cccgccccgg tcgtcccgga cgatccccgc
     3061 ctgcgcgaga agggcgcgac cttcatcacc cttgccaggg acggcgagct gcgcggctgc
     3121 atcggcagcc tgcggcgttc gcgcgagctc ggcgaggacg tgatccacaa cgcgctcgcg
     3181 gcggccttcg aggattcgcg cttcgagccg ctcgccgccg aagagctcga cgcggtgacg
     3241 atcgaggtct ccatcctctc cgagcccgag ttcctcgact tcttcggcga ggaagagctc
     3301 atcgcccagc tgcgccccgg cgaggacggg ctgatcatct tctccggctg ccgcagcgcc
     3361 accttcctgc cccaggtgtg ggagcagctg cccgagccgc gccagttcct cgccgcgctc
     3421 aagcacaagg ccggcctgcc caccaaccgc gaggtggtcg agctcatggc cgcgcgttat
     3481 cacgtcgaga agtggaagga gaccgaacgg gagccctcat gagcacgaag cccgagcctg
     3541 cagccgacgc aggccgcacc gaggtcggca gccgccatcc cgcgcgctat tggcatcgca
     3601 tcgacgacgg ccgctaccag tgcgacctct gtccgcgcct gtgcaagctc caccccggcc
     3661 aacgcggtgc ctgcttcgtg cgcatgcgcg agggtgacga catgctgctc accacctacg
     3721 gtcgcagctc gggcttctgc atcgacccga tcgagaagaa gccgctcaac catttctacc
     3781 cgggcagcaa ggtcttctcc ttcggcaccg ccggctgcaa cctggcgtgc aagttctgcc
     3841 agaactggga catctcaaag tcgcgcgacc tcgacacgct gatggacgag gcctcgcccg
     3901 ccgagatcgc cgacaccgcc ctgcactggg gctgtcacag cgtcgccttc acctacaacg
     3961 acccggtgat cttcgccgag tacgccatgg acgttgccga cgcgtgccat gcgcgcggcc
     4021 tgaagaccgt cgcggtgacc gcgggctaca tttccgagtg cgcgcgtcgc gacttcttct
     4081 cgcgcatgga tgcggccaac gtcgatctca agggcttcac cgacgacttc tacgtcaagc
     4141 tgtgtggcgc ccacctgcag ccagtgctcg acaccctggt atggctgcgc catgaaaccg
     4201 acgtatgggt cgagctcacc accctgctga tccccggaca caacgacacc gacagcgagg
     4261 tcgccgcgct ggcgaaatgg gtgcgcgagg agctcggggc cgaggtgccg ctgcatttca
     4321 gcgccttcca ccccgacttc aagatggacg atctgccgcc cacgccgccc gccacgctca
     4381 cgcgcgcgcg ccgcatcgcg ctcgacgccg ggctcaagca cgtatacacc gggaacgtgc
     4441 atgacaccga gggcgacacg acccactgcg cgagctgcgg cgaggccctg atcgtgcgcg
     4501 actggtacga gatccgccgc tacgccctcg gcgccgacgg ccgctgcccg cattgcggca
     4561 gcgtgctcgc cggccgcttc ggcgcggttg gcgccgcggt cggcgaggcc ttcggcgcgc
     4621 gccgcatccc ggtcgccatc caccgtcacg gcacctgagt tcattcggcc cgcaacgtga
     4681 aacttcgaaa caccctcatc agcattcccg cacagggcgc ctggctcgac ggcctgctcg
     4741 cccatgcgcc ggacgtccgc gggcttgccg tcctgccgca atcgagcggc caccctgcgc
     4801 tcgacaccgg gccgcggccg ctggagctcg cactgcaatc acgcggcttc gccaccatgc
     4861 gcctcgacct gctcacgcgg caggaggcgc tgcgcgaccc cgacgcgtcg ttcaacatca
     4921 cccgcctcac cgagcgcatc ctcgcagcgg tcgagtggat cgcccatcag ccaccgctcg
     4981 ccgggctgca gctcggcctc gtggcacacg acaccggctg cgccgccgcc atccgcgcgg
     5041 ccgtcaaggc gccggagacc ttcgcggcga tcgcctgcgt cgacggccgg gccgatctcg
     5101 cgggggccga gcccctgcgc cacctgcgtt gcccggtgcg cttcatcgtc accccgggcg
     5161 tgccggagag cgcgatcctg gagaaggcct tttccctgct tggggggccg cgccactggc
     5221 tcgcgctgcc cgacgccggc gacgcccgcc agcaggagct cctgcaggcg cgagcggtca
     5281 cgagctggct cgaacagcac ctcgccgtgg tcgagcgcgt aagagtcgaa tagcttcggg
     5341 gcccgtccaa tccatgtccg ggatgtcggt ttcctcgctc ggtggcgctt acgcggcgtg
     5401 gcggcagacc accacgatgc atgacgcccg cgctgccgac gccgccgcag cgccggcgat
     5461 ggcgcaaggt ggcggcgaca cacaagcgac gcctgcgggg ctggccgacg cgctctccga
     5521 ggccgagcag cgccaggtcg ccgagctcgc gaagcgcgac cgcgaggtgc gcgcccacga
     5581 gatggcgcat gtcgccgcgg gcgccggcct ggtgacgcgg ggcgccagct acacctacca
     5641 gaccggcccc gacggccagc gctacgcgat cggtggcgag gtcgggatcg acacctcgcc
     5701 gggccgcact cccgaggaga ccctcgccaa ggccgagcgc atccgcgccg ccgcgctcgc
     5761 ccccgcggag ccatcgggcc aggaccgcca ggtggccgcc caggctgccc gcatggcgaa
     5821 cgatgcgcgc ctggagatcg cccgccgcga gttcgctcag ggcgacacgg gcgccgaggc
     5881 cacccgcgac ggcgccgtcg atcgcggcat gcgtgcggca caggcctatt ccgaagggct
     5941 cgctccgcgc caggcgccca ctctttcggc ctccgcctga agcctccggc ccgcattggc
     6001 gccatcaggc cgtgcgctgg cgggccggga tgaaggataa ttctgccttt gccggccacc
     6061 gcgtccccac cgccatcccg cccctccagg caaggatggc caccgccgta gacgacgctc
     6121 aagaaaccac gatgtccttc tccctcgacg ccctcctctc ccggctcgcc accgtcaagc
     6181 tgcccaagcc cggcggcagg ctcgagctcg acgcgttggc cggctcggcc gacgcgctcg
     6241 ccatcgccca gctcgccagc cgcggccgca tgttggtggt gatcaccgcc aacccgctcg
     6301 acgcccagcg cctccaggac gagatcgcct gggtcgcgcc cggcctgcgc gcgcacctgc
     6361 tgcccgactg ggagaccctg ccctacgaca gcttctcgcc ccaccaggac ctgatctccg
     6421 agcgcctgtc cacgctctac gcgatcagcc gcggcgagac cgacctcgtg ctggtgcccg
     6481 cctcgaccgc gctctaccgc atggcgccgc cgagctacct cgccgcctac accttcttcc
     6541 tcaagcaggg cgagaagctc gacgtcgagc agttcaaggc gcagatggcg ctcgccggct
     6601 acgcgcatgt gacccaggtg gtgagcccgg gcgagttctc ggtgcgcggc gggctggtcg
     6661 atctcttccc gatgggctcg ccgctgccct tccgcatcga cctcttcgac gacgaggtcg
     6721 agagcatcaa gaccttcgac cccgacaccc agcgcacggt gtatccgacc aaggagatcc
     6781 gcctgctgcc ggcgcgcgag ttccccctcg acgacaaggg ccgcacgcgc ttccgcagcc
     6841 gcttccgcga gaccttcgag ggcgacccga cgcgcgcctc gatctacaag gacgtctcca
     6901 acggcatcgc gccggctggc atcgagtact acctgccgct gttcttcgac gacaccgcga
     6961 ccctgctcga ctacctgccc gccgagacgg cggtgctgct gcatcgtgac gtgccggcgg
     7021 cgatcgccga gttctggaag gacacgcgct cgcgccatga cctgctcaag ggcgaccgca
     7081 cccgccccgt gctggcgccc gagcagctct tcctctcgga cgaggccttc ttcgtcgcgc
     7141 tgaagaacct gcctcgcctg agcatcggtg ccgaggcaag cgccgaagcc gccgatgcac
     7201 tcgccctgcc gccgcccgag gtcgcggtcg agcgcaaggc caccgacccg ctgcacaagt
     7261 tgaaggcctt cctcgacggc ttcgacggcc gcgtgctgct gctgtcggac tcgcccggcc
     7321 ggcgcgagac catggccgag ttctttgccg aatacggcgt caagcccgag gccagcgccg
     7381 acttcggcgc cttcctcgat ggcgacgccc gcctcgcgct cggcgtcgcc ccgctcgcgc
     7441 gcggcttcgt gctgccggct gccaggctcg cggtgctgac cgagaccgag ctctacgccg
     7501 ccaccgcgcg cagccgcgtg cgccgcgacg cgcgcaaggc cgccaccatg gaaggctggc
     7561 tgcgcgacct ttcggaactc aaggtcggcg acccggtggt gcatgtgtcg cacggcatcg
     7621 gccgctacct cggcctcatc cacatgaacc tgggcgaggg cgacaccgag ttcctgcacc
     7681 ttgaatacaa cggcggcgac aagctctacg tgccggtgtc gcagctgcac gtgatcaccc
     7741 gctacgccgg cgccgacccg gaggccgtgg acctgcaccg cctcggctcg ggccagtggg
     7801 agaaggccaa gaagaaggcg gcgatgcagg tgcgcgacac cgccgccgag ctactcgcgc
     7861 tctacgccca gcgcgccgcc cgccccggtc accgcttcga cttcaagcag cacgacctgg
     7921 aggccttcgc cgagggcttc ggcttcgaga ccacgcccga ccagcaatcg gccatcgacg
     7981 cggtggtggg cgacatgaag tccggccgcc cgatggaccg cctggtgtgc ggcgacgtcg
     8041 gcttcggcaa gaccgaggtc gcgctgcgcg ccgccttcat cgcggtcgcc gacggcaagc
     8101 aggtggtggt gctgtgcccg accaccctgc tcgccgaaca gcactaccag accttcgccg
     8161 accgcttcgc cgactggccg atcaagctcg ccgagctgtc gcgcttcaag tccgccaagg
     8221 aacaggccga ggccctgcag cagctcacgg aaggcaaggt cgacatcatc atcggcaccc
     8281 accgcctgct gcagaaggat gtcgtcttca agcgcctcgg gctggtgatc atcgacgagg
     8341 agcaccgctt cggcgtgcgc cagaaggagg ccttgaagca gctgcgctcc gaggtcgaca
     8401 tcctgaccct gaccgccacg ccgatcccgc gcaccctggg cctggcgatg gagggcctgc
     8461 gcgagttctc ggtgatcgcc acgccgccgc agaagcggct gtcgatcaag accttcgtgc
     8521 agccttccag ccgcggcgtg atccgcgagg cggtgctgcg cgagttcaag cgcggcgggc
     8581 aggtctactt cctgcacaac gaggtcgaca ccatcgacaa cataaaggac gacctcaagg
     8641 agctgctgcc cgaggcgcgc atcgtcgtcg gccacggcca gctccccgag cgcgagctcg
     8701 agcgcgtgat gcgcgacttc acccagcagc gcgccaacct gctgctgtgc accaccatca
     8761 tcgagaccgg catcaacatc cctaccgcca acacgatcat catcaaccgc gccgaccgct
     8821 tcggcctggc gcagctccac cagctgcgtg gccgcgtcgg ccgcagccac caccaggcct
     8881 acgcctacct gctgaccatg ccgggcgcca agcccaccgc gcaggcacag aagcggctcg
     8941 aggcgatcgc gatgatggaa gacctcggct ccggcttcta cctggcgatg cacgacctcg
     9001 agatccgcgg cgccggcgag gtgctgggcg agaaccagtc gggcgagatc cagcaggtcg
     9061 gcttcagcct gtacaccgag atgttgaagc gcgcggtcaa ggacctgcag gccggcaagg
     9121 agcccgacct gtcgcagccg ctggaggtcg tgtccgagat caacctgcac accccggcgc
     9181 tgctgcccac cgactactgc cccgacgtgc aggagcgcct gacgctgtac aagcgcctgg
     9241 ccaactgcga gctggaggaa gacctgcgtt tcctgcagga ggaactcatc gaccgcttcg
     9301 gcgaactccc gccgcagacc gccgccctga tcgagaccca ccgcctgcgc atgctggtca
     9361 aggactacgg cgtgcacaaa ctcgacgcct cggacgcgca gatcagcgtg cagttcgcca
     9421 aggacgcgcc gatcgatccg gtcaaggtca tcttcctgat ccagaaggac cgcagcacca
     9481 agatggccgg ccccgagaag ctggtgcgcc gcgccagcct gcccaacctc aaggagcggg
     9541 tgaaggcggt gaaggacctg ctcgacgcgg tgagggccga tgcgccgaag gccgacggcg
     9601 tgaaggccga cggcgagaag cctggcggcg cgaaggcgaa ggcgctgaag acctgagcga
     9661 ggacgcaccg cgatgctgat caactgcact gcctaccagc acggccgcaa gcacgccgac
     9721 atcccggtcg aggacatcag cgagtacgtg cagcagcccg acaccttcgt ctgggtcgcc
     9781 ctcaaggacg ccagcgccga agagctcgcg gtgatgaagg aggagttcgg cctgcacgag
     9841 ctcgccatcg aggacgccaa ccaccgccac cagcgcccca aggtcgagga gtacgacgac
     9901 gagctcttcg tggtcatgca cctggtcgag gagcgcgagg gcaagctcga ggtcggcgag
     9961 gtgcatgtct tcgtcggcgc caactacatc ctgtcggtgc gcaacaacca cgcgcgcgac
    10021 ttcctcggcg tgcgcgcacg ctgcgagcgc gagccgagga tgctcgccaa gggaccgggt
    10081 tacgtgctgt atgcgctgat ggacgcggtg gtcgacggct acttcccgct catcgacaag
    10141 ctcgagaccg aggtcgaggc gctggaggag cgcatcttca ccaagggcgc gggcaattcc
    10201 aacatgcgcc ggctttaccg cctcaagcgc aaggtcaccc tgctcaagca cgccgtgctg
    10261 ccgctgatgg aagccgccgg caagctgcac agcgggcgcg tgccggaagt ctgcgccaag
    10321 agccggcact atttccgcga cgtgtatgac cacctcgccc gcatcgacgc ctcgctcgac
    10381 agcgtccgcg agaccatcgg cactgccatc caggtgaaca tctcgctggt caccatcgac
    10441 cagaccgagg tcagcaagcg cctcgccgcc tgggccggca tcttcgccgt cgccaccgcc
    10501 ttcgccggca tctggggcat gaacttcagc cacatgccgg agctggaatg ggagtacggc
    10561 tacttcgccg gcctcggcgt catcgccagc gccagcgcct tcctgtggtg gcgcttccgc
    10621 aaggccaggt ggctctaggg cccccattcg cggctgccgc cgctcctaca gggcgctcgc
    10681 gccacgtcgg tttctg
//
LOCUS       DAOTIN010000113        10666 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_7362_length_10666_cov_7.905852, whole genome shotgun sequence.
ACCESSION   DAOTIN010000113 DAOTIN010000000
VERSION     DAOTIN010000113.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 10666)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 10666)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10666
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_7362_length_10666_cov_7.905852"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1106
                     /gene="nuoN"
                     /locus_tag="P5537_13650"
     CDS             <1..1106
                     /gene="nuoN"
                     /locus_tag="P5537_13650"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_process: GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoN"
                     /protein_id="HRV79130.1"
                     /translation="VTANHMLPMYIGLEMMSLALYTMVAFDRDSARSTEAAMKYFVLG
                     ALASGLLLYGMSMVYGATGTLEFSGVAQALYNQTANQTVLMFGLVFLVAGICFKLGVV
                     PFHMWVPDVYQGAPTAVTLVIATAPKLAAFAMAVRLLIWALFDIAEEWQMMLILVAAA
                     SIVLGNLAAIAQQNIKRMLAYSGISHMGFMLLGLLAGVVEGDRHFALNAYSSAMFYAI
                     SYVIMSLASFGMLILLSRAGFEAENIDDFKGLNKRSSWYALMMLFVMFSMAGVPFFIG
                     FFAKLSVLQAVVAAGYFWLAVLAVVMSVIGAFYYLRVVKVMYFDDPIDASPIHAAPEV
                     RVMLSANGLAIAALGLAPQALMSLCAFALLRSL"
     gene            1114..1446
                     /locus_tag="P5537_13655"
     CDS             1114..1446
                     /locus_tag="P5537_13655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2818 family protein"
                     /protein_id="HRV79131.1"
                     /translation="MGAEAGVFLLLAIAITMANLPFVFDRILFVRKPPAGARKGLGWC
                     FAELVLLYFIVGGLAALIEAQSHGRVYEQGWAFYATTFCLFVVFAFPGFTWTYLWHAG
                     RRPPEVGA"
     gene            1443..2012
                     /locus_tag="P5537_13660"
     CDS             1443..2012
                     /locus_tag="P5537_13660"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HRV79132.1"
                     /translation="MSGVGGDALHEHTLESEPVYQGALLKVWRDRVELPDGSHSVREY
                     IRHPGAVVVVALDESGALVFERQFRYPLQRAFLELPAGKIDAGEDILACARRELREET
                     GFAAVHWEYVGVMHPCIGYSDERIEVFFAHGLSQTERALDDGEFLEVLSLRTDEVEQA
                     IRTGRITDAKTITAYYLSLPRIQECLQGR"
     gene            complement(2038..3312)
                     /locus_tag="P5537_13665"
     CDS             complement(2038..3312)
                     /locus_tag="P5537_13665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HRV79133.1"
                     /translation="MSQPDGFHLFPRIARIDASQWDALVDASCASPAPCIRHAFLHAL
                     EESGCVGGRSGWTPAHATLWQDGALRAAMPLYLKAHSWGEYVFDWAWAEAYQRHGLDY
                     YPKWLGAVPFTPIPGPRLLGGGDDARRELLAALLSNARESGLSSLHLLFPLDSERGLL
                     EAAGLMIREGVQFHWENPPAVGDPVSPGTGAAFSAPRRRWTDFEDFLASLSGAKRRKI
                     RQERRRAAAHALHLQWLDGHEARDEDWAFFAHCYATTYALHRSTPYLSAEFFVRFARS
                     MPGAVRLLVARRDGHPVAAAFFLCDREALYGRYWGCVEDLPFLHFELCYYQAIEYCLR
                     HGLARFEGGAQGEHKLARGLLPVRTFSAHWLADARFRGAVDEWLVRERAGVGHYLDEL
                     EGHSPFRRDTDGAGGAGTAEATDAERGQCPPR"
     gene            3589..5217
                     /locus_tag="P5537_13670"
     CDS             3589..5217
                     /locus_tag="P5537_13670"
                     /EC_number="6.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD+ synthase"
                     /protein_id="HRV79134.1"
                     /translation="MNAHAHAPVSIAVAQLNLTVGDLVGNADRIIAALDEARAAGAQL
                     MLTPELALSGYPPEDLLLRPDFYRACAREVERIAAAAQGVTVVLGHPVEDGSERYNAA
                     SVLRDGVVLARYHKSLLPNYEVFDEERYFEAGGTACVFECGGVRFGLNICADVWERGP
                     AEAARAAGAQVLLALNASPYHMNKQVQRLEVLRARVAETGLPVLYCNMVGGQDELVFD
                     GASFALDARGGLGLQLGSFVERVAVVTYAAGGWSGGEQVPARTLEAEVYEALRIGVRD
                     YLAKNRFPGAIIGLSGGIDSALTLAIAVDALGADKVRAVMMPSPYTAQMSLDDSRDMV
                     ARLGVRYDEIAIEPAMDVFAELLAAQFAGLPADTTEENLQARIRGMLLMALSNKTGAI
                     VLTTGNKSEMATGYATLYGDMAGGFAVLKDLYKTFVFRLSNWRNTVSPVIPQNIIDRP
                     PSAELKPDQKDQDSLPPYDMLDAIIQAYMERDESPRDIVAAGFPEGEVRRVVGMLKRN
                     EYKRRQAPVGIRVTQRGFGRDWRYPITSRYQDEF"
     gene            5234..5572
                     /locus_tag="P5537_13675"
     CDS             5234..5572
                     /locus_tag="P5537_13675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017373484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HRV79135.1"
                     /translation="MKKIEAIIKPFKLDEVREGLSEVGITGLTVTEVKGFGRQKGHTE
                     LYRGAEYVVDFLPKIKVEVVLADDIVDQAVEAIVKAAHTGKIGDGKIFITPVEQVIRI
                     RTGETNEAAI"
     gene            complement(5606..6685)
                     /locus_tag="P5537_13680"
     CDS             complement(5606..6685)
                     /locus_tag="P5537_13680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Smr/MutS family protein"
                     /protein_id="HRV79136.1"
                     /translation="MSRRAAASRPSGSPQGRDAQGPAAKPASPFAALRKQLQRAQPAP
                     SPAPSPAKRIRHPLEEDTAGARADRAQEPDAEELELFRRSVGAVRPVRGTDRVEIDRP
                     RPAPLPRTQAVEDEESEEPARARPETDPLRAAYEGVVPLKETGRVALDTPLRHHARGT
                     HPAPALRPDAIVLPADADVSDPAALFRAVVGNARPVADRNRVELERPQPAPAPLKREE
                     DERAALDESLAAPLTFEDRLDMGDEAAFLRTGLPRRVLTDLRRGRWVLQGQIDLHGLT
                     RDEARAALAAFLHDALAQGKRCIRVIHGKGHGSPGKVSILKQLSRGWLAQREEILAFC
                     QAGPHDGGGGALLVLLRAQNAVTRA"
     gene            complement(6694..7647)
                     /gene="trxB"
                     /locus_tag="P5537_13685"
     CDS             complement(6694..7647)
                     /gene="trxB"
                     /locus_tag="P5537_13685"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HRV79137.1"
                     /translation="MTTKHARLLILGSGPAGYTAAVYAARANLNPVLITGLAQGGQLM
                     TTTEVDNWPADADGVMGPDLMARFQKHAERFNTEMIFDHIHTVKLGEKPFRLVGDSGE
                     YTCDALIISTGATAKYLGLPSEEKFAGRGVSACATCDGFFYRNQEVAVIGGGNTAVEE
                     ALYLANIAKKVTLVHRREKFRAEKIMIDKLMEKVAAGKIELALNATLDEVLGDNTGVT
                     GMRIKDVNNGATRDVALQGVFIAIGHKPNTDIFEGQLEMEGGYIVTQGGRNGNATQTS
                     IPGVFAAGDVQDHIYRQAVTSAGTGCMAALDAERYLDALGA"
     gene            7885..8556
                     /locus_tag="P5537_13690"
     CDS             7885..8556
                     /locus_tag="P5537_13690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004371833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HRV79138.1"
                     /translation="MTQATAVSVVALKTFPLFHGLSDDSLASIARVSMMRRFPRGQSV
                     VCAGDRPDYVYLVLTGSLKVVVSDEDGREVILSILGQGELFGEMGMFDERPRSASVIA
                     VVPADLVLISKQDFRRIMQDSFDVSWRIMCNLAERLRNADRKIESLALMDVYGRVARL
                     LIEMAEDVGGQSVVVRRISKQDIAKMIGASREMVSRVMKDLGQQGLIEEGPDGILLRE
                     RLNDV"
     gene            8667..>10666
                     /locus_tag="P5537_13695"
     CDS             8667..>10666
                     /locus_tag="P5537_13695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK 4TM domain-containing
                     protein"
                     /protein_id="HRV79139.1"
                     /translation="MLSRSSSRSQPLPEKISLLLQEARWLILGVVSLYVGMILVGYSE
                     SDPGWSHASDVTRVANPGGRFGAWLADLLLYLFGISSWWWVVFLGYSLLWGFRRLKNR
                     LELDHRSFIFVMIGFFVVLITSSALEFLRFHSHGAPVPLEPGGLIGMELAQFVRRSFG
                     FTGGTLLLLALMATGLSLFTGVSWLALMERVGLAIEQSVLGVQQAWLRWQDRRVGREV
                     AHKREEVVQTRRKKVEKAEPAPLRIEPAVVVVPKSERVEKERQQTLFQDAAEGVIPPV
                     ALLDPASGGVEPPSPEALEFTSRLIETKLADFGVEVKVLAAYPGPVITRYEIEPATGV
                     KGSQVVNLAKDLARALSLVSIRVVETVPGKSCMALELPNPKRQMVRLSEIIGSKVYQD
                     AHSPLTVVLGKDIGGQPVVADLAKMPHLLVAGTTGSGKSVGINAMILSLLYKSEPDRV
                     RLIMVDPKMLELSIYEGIPHLLAPVVTDMKHAANALNWCVAEMDKRYKLMAAVGVRNL
                     AGFNKAVQEARKAEAPLTNPFSISPENPEPLEPLPYIVVVVDELADMMMVVGKKVEEL
                     IARLAQKARAAGIHLILATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQMGA
                     ETLLGMGDMLYLAPGTGLPVRVHGAFVADDEVHKVVDHLKKIG"
BASE COUNT         1551 a         3532 c         3759 g         1824 t
ORIGIN      
        1 tggtcacggc caaccacatg ctgccgatgt acatcggcct cgagatgatg tcgctcgcgc
       61 tgtacacgat ggtcgccttc gatcgcgact cggcgcgctc gaccgaggcg gcgatgaagt
      121 acttcgtgct gggcgcgctg gcctcgggcc tgctgctgta cggcatgtcc atggtgtatg
      181 gcgcgaccgg cacgctcgag ttctcgggcg tggctcaggc gctctacaac cagaccgcga
      241 accagaccgt gctgatgttc ggcctcgtct tcctggttgc cggcatctgc ttcaagctcg
      301 gcgtcgtccc gttccacatg tgggtgcccg acgtctatca gggcgcgccc accgcggtga
      361 cgctggtgat cgccaccgcg cccaagctcg ccgcgttcgc gatggcagtg cgcctgctga
      421 tctgggcgct tttcgacatc gccgaagagt ggcagatgat gctgatcctg gtggcagccg
      481 cctcgatcgt gctcggcaac ctggccgcga tcgcgcagca gaacatcaag cgcatgttgg
      541 cctactcggg catctcgcac atgggtttca tgctcctcgg cctgctcgcc ggcgtggtcg
      601 agggcgaccg ccacttcgcg ctcaacgcct acagctcggc gatgttctat gcgatctcct
      661 acgtgatcat gagcctggcc tcgttcggca tgctgatcct gctgtcgcgc gccggcttcg
      721 aggccgagaa catcgacgac ttcaaggggc tcaacaagcg cagctcgtgg tatgcgctga
      781 tgatgctctt cgtgatgttc tcgatggcgg gcgtgccctt cttcatcggc ttcttcgcca
      841 agctgtcggt gctgcaggcg gtggtcgccg cgggctattt ctggcttgcg gtgcttgcgg
      901 tggtgatgtc ggtgatcggg gcgttctact acctgcgcgt ggtcaaggtg atgtacttcg
      961 acgatccgat cgatgcctcg ccgatccatg ccgcgcccga agtgcgcgtg atgctctcgg
     1021 ccaacggcct cgcgatcgcg gccctcggcc tcgctccgca ggcgctgatg tccttgtgcg
     1081 cgttcgcgct gctgcgctcg ctctgatccg gcggtgggtg cagaggccgg cgtcttcctg
     1141 ctgttggcca tcgccatcac gatggccaac ctgcctttcg tcttcgaccg catcctcttc
     1201 gtccgcaagc cgccagccgg tgcccgcaag gggctcggct ggtgttttgc cgagctggtg
     1261 ctgctttatt tcatcgtggg cgggcttgcc gccctgatcg aggcgcaatc ccacggccgg
     1321 gtgtatgagc agggctgggc gttctatgcc acgaccttct gcctgttcgt cgtgttcgcg
     1381 tttcctgggt tcacctggac ctacctgtgg cacgcggggc gcaggccgcc cgaggtgggc
     1441 gcatgagcgg ggtcgggggg gacgcgctgc acgaacacac gctcgagagc gagcccgtct
     1501 accagggtgc gctcctcaag gtgtggcgcg atcgcgtcga attgccggac ggcagccaca
     1561 gcgtgcgcga gtacatccgc catcccggcg cggtggtggt ggtggcgttg gacgagagcg
     1621 gggcgctggt gttcgagcgc cagttccgct atccgctgca gcgtgccttc ctcgagcttc
     1681 ccgccggcaa gatcgacgcc ggcgaggaca tcctggcctg cgcgcggcgc gagttgcgcg
     1741 aggagaccgg cttcgccgcg gtgcattggg aatacgtcgg ggtgatgcat ccctgcatcg
     1801 gctattcgga cgagcgcatc gaggtcttct tcgcacatgg gctttcgcag acggagcgtg
     1861 cactcgacga cggcgagttc ctcgaggtgc tgagcctgcg cacggatgag gtggagcagg
     1921 cgatccgtac cgggcgcatc accgacgcca agaccatcac cgcgtattac ctgtccttgc
     1981 cgcgcatcca ggagtgcttg cagggacgct gactgggctg gttgaggggc gaagcggtca
     2041 gcgcggtgga cattgtccgc gctcggcgtc cgtggcctcc gccgttcctg cgccgccagc
     2101 cccatccgta tcgcgccgaa acgggctgtg tccttccagc tcgtccaggt agtgccccac
     2161 gcccgcgcgc tccctcacca gccattcgtc caccgcgccg cgaaagcgcg catccgcgag
     2221 ccagtgcgcc gagaaggtac gcaccggcag caggccgcgg gcgagcttgt gctccccctg
     2281 tgcgccgccc tcgaagcggg cgaggccgtg ccggaggcaa tactcgatgg cctggtagta
     2341 gcagagctcg aagtgcagga agggcaggtc ctcgacgcag ccccagtaac gcccgtacag
     2401 cgcctcgcga tcgcacagga agaaggccgc ggcgaccggg tggccgtcgc ggcgcgcgac
     2461 cagcaggcgc acggccccgg gcatgctgcg cgcgaaccgc acgaagaatt ccgcgctgag
     2521 atagggcgtg gagcggtgca gcgcgtaggt ggtcgcgtag caatgggcga agaacgccca
     2581 gtcctcgtcc cgcgcttcat ggccgtccag ccactgcagg tgcagggcat gcgcggccgc
     2641 acggcggcgt tcctggcgga tcttcctgcg cttggcgccg gacaggctgg cgaggaaatc
     2701 ctcgaagtcc gtccagcgtc gtcgcggcgc ggagaacgcc gcacccgtcc caggggaaac
     2761 agggtccccc acggcgggcg gattctccca atggaactgc acgccctcgc ggatcatcag
     2821 cccggccgcc tccaggagcc cccgctcgct gtcgagcggg aagagcaggt gcagcgacga
     2881 caggccgctt tcccgcgcgt tcgagagcag cgctgcgagc agctcccggc gcgcatcgtc
     2941 tccgccgccg agcaggcgcg gcccgggaat gggggtgaag ggcacggccc cgagccactt
     3001 gggatagtag tccaggccgt ggcgctggta ggcttccgcc caggcccagt cgaagacgta
     3061 ctcgccccag gagtgcgcct tgagatagag cggcatggct gcgcgcaaag cgccgtcctg
     3121 ccaaagggtg gcgtgcgcgg gcgtccagcc gcttcggccc cccacgcaac cgctctcttc
     3181 gagggcatgc aggaaggcgt ggcggatgca cggtgctggg cttgcgcagc tcgcgtcgac
     3241 cagggcatcc cactggcttg cgtcgatgcg ggcgatgcgg gggaagaggt ggaatccgtc
     3301 gggctggctc atggaggctg gggcggggac agcgcacacg gctgcccgtt ttttgtgcag
     3361 tgcgacgata cgtcgccgcg acaggcactt gcaagtgctg tccacgcctt gtccacaggc
     3421 ttgcgcacct cggctgtggg ttcctgcatc gtaatccacg gtctcgccgc gagcgtggcg
     3481 gcggccgggt gcgggacggc gcccgggcat gaaggtgcgt gcacgcatgc gatcgggcgc
     3541 acgcggggcc tgtcgtggag cttcgccgaa gcggtatagt tccgccccat gaacgcacat
     3601 gcacatgccc ccgtctccat cgccgtcgcc cagctcaacc tgaccgtggg cgatctcgtc
     3661 ggcaacgccg accgcatcat cgccgcgctc gacgaagcgc gcgcggccgg tgcgcagctg
     3721 atgctcacgc ccgaactcgc gctctccggc tatccgcccg aggatctgct gctgaggccg
     3781 gatttctacc gcgcctgcgc gcgcgaggtc gagcgcatcg ccgcggcggc gcaaggcgtc
     3841 acggtggtgc tcggccaccc ggtggaagac ggtagcgagc gctacaacgc cgcctcggtc
     3901 ctgcgtgatg gcgtcgtgct ggcgcgctac cacaagagcc tgctgcccaa ctacgaggtc
     3961 ttcgacgagg agcgttactt cgaggccggc ggcacggcct gcgtgttcga gtgtgggggc
     4021 gtgcgcttcg ggctcaacat ctgcgccgac gtctgggagc gtggccccgc cgaggccgcg
     4081 cgtgcggcgg gggcgcaggt gctgctggcg ctcaatgcct cgccctacca catgaacaag
     4141 caggtccagc gtctcgaggt gctgcgcgcg cgcgtggccg agaccggcct gccggtcttg
     4201 tactgcaaca tggtgggcgg ccaggacgag ctcgtcttcg atggcgcctc cttcgcgctc
     4261 gacgcccggg gtggtctcgg gctgcagctc ggcagcttcg tcgagcgcgt ggcggtcgtc
     4321 acttacgccg ccgggggctg gtcggggggc gagcaggttc ccgcacggac gctggaggcc
     4381 gaggtgtatg aggcgctgcg catcggggtg cgcgactatc tggccaagaa ccgcttcccg
     4441 ggcgcgatca tcggcctgtc gggcgggatc gactcggcgc tgaccctcgc gatcgcggtc
     4501 gatgcgctcg gcgccgacaa ggtgcgtgcg gtgatgatgc cctcgcccta caccgcgcag
     4561 atgagcctgg acgactcgcg cgacatggtg gcgcggctgg gcgtgcgcta cgacgagatc
     4621 gcgatcgagc cggcgatgga tgtgttcgcc gaactgctcg cggcgcagtt cgccggcctg
     4681 ccggccgaca ccaccgagga aaacctacag gcgcgcatcc gcggcatgct gctgatggcg
     4741 ctgtccaaca agaccggcgc gatcgtgctc accaccggca acaagagcga gatggccacc
     4801 ggctacgcga cgctctacgg cgacatggcc ggcggcttcg cggtgctcaa ggacctctac
     4861 aagaccttcg tcttccgcct gtcgaactgg cgcaacacgg tgagtccggt gattccgcag
     4921 aacatcatcg accggccgcc atcggccgag ctcaagcccg accagaagga ccaggacagc
     4981 ctgccgccct acgacatgct cgacgccatc atccaggcct acatggagcg cgacgagtcg
     5041 ccgcgcgaca tcgtcgccgc gggcttcccg gagggcgagg tgaggcgcgt ggtgggcatg
     5101 ctcaagcgca acgagtacaa gcgtcgccag gcaccggtgg gcatccgcgt gacccagcgc
     5161 ggcttcggca gggattggcg ttatccgata acatcgcgct accaggacga attctgaaag
     5221 aggagcaagc cggatgaaga agatcgaggc gatcatcaag ccgttcaagc tggacgaggt
     5281 gcgcgagggt ctgtcggagg tgggcatcac cggcctgacg gtgaccgagg tcaagggctt
     5341 cggccgccag aaaggccaca ccgagctcta tcgtggggcc gagtacgtgg tcgacttcct
     5401 gcccaagatc aaggtcgagg tcgtgctcgc cgacgacatc gtggatcagg cggtcgaggc
     5461 gatcgtcaag gccgcgcaca cgggcaagat cggcgacggc aagatcttca tcacgccggt
     5521 ggagcaggtc atccgcatcc gcaccggcga gaccaacgaa gcggcgatct gatcgccgcg
     5581 cggcgacgtc cgcgcctgga agcgttcagg cgcgcgttac cgcgttctgc gcgcgcagca
     5641 gcaccagcag cgcgccgcca ccgccatcgt gcgggccggc ctggcagaag gcgaggatct
     5701 cctcgcgctg ggccagccag ccgcgcgaaa gctgtttcag gatcgacacc ttgcccggcg
     5761 agccgtggcc cttgccgtgg atcacccgga tgcagcgctt gccctgggcg agcgcgtcgt
     5821 gcaggaaggc cgccagcgcg gcgcgcgcct cgtcgcgggt gaggccgtgc aggtcgatct
     5881 ggccctgcag cacccagcgc ccgcggcgca ggtcggtgag cacccggcgc ggcagcccgg
     5941 tgcgcaggaa ggccgcctcg tcgcccatgt cgaggcggtc ctcgaaggtg agcggtgcgg
     6001 cgagcgattc gtcgagcgcc gcgcgttcgt cctcctcgcg cttgagcggc gccggcgctg
     6061 gctgcggacg ctccagttcc acccggttgc ggtcggcgac cgggcgtgca ttgcccacca
     6121 ccgcacggaa gagcgctgcc ggatcgctga cgtcggcgtc cgctggcagc acgatggcgt
     6181 ccggtcgcag cgctggcgcg ggatgcgttc cgcgggcatg gtggcgcagc ggcgtgtcga
     6241 gcgccacccg gccagtctcc ttcagcggca ccacaccctc gtaggcggcg cgtagcgggt
     6301 cggtctcggg gcgcgcgcgg gcgggttcct cggattcctc gtcctccacg gcttgtgtgc
     6361 gcggcagcgg ggcagggcgg gggcggtcga tctcgacgcg gtccgtgccg cgcaccggtc
     6421 gtacagcgcc gacgctgcgc cggaagagct cgagctcctc cgcgtcgggc tcctgcgcgc
     6481 gatcggcccg tgcgccggcg gtgtcttcct cgagcggatg acggatccgc ttcgccgggg
     6541 agggggccgg ggagggggcc ggctgtgcgc gctgcagctg cttgcgcagg gctgcgaagg
     6601 gtgatgcagg cttcgcagcc gggccttgcg cgtcgcgtcc ctgcgggctg ccggacgggc
     6661 gcgatgcggc ggcgcggcgg ctcatcggtc tgctcaggcg ccgagggcgt cgaggtagcg
     6721 ctcggcgtcg agcgcggcca tgcagccggt gccggccgag gtcacggcct ggcggtagat
     6781 gtggtcctgc acgtcgccgg cggcgaacac gcccgggatg ctggtctgcg tggcgttgcc
     6841 gttgcggccg ccctgggtga cgatgtagcc gccttccatc tcgagctggc cctcgaagat
     6901 gtccgtgttg ggtttgtggc cgatggcgat gaacacgccc tgcagcgcga cgtcgcgggt
     6961 ggcgccgttg ttcacatcct tgatgcgcat cccggtgacg ccggtgttgt cgccgaggac
     7021 ttcgtccagg gtggcgttga gcgcgagctc gatcttgccg gcggcgacct tctccatcag
     7081 cttgtcgatc atgatcttct cggcgcggaa cttctcgcgg cgatggacca gcgtgacctt
     7141 cttcgcgatg ttggcgaggt agagcgcctc ctcgaccgcg gtgttgccgc cgccgatcac
     7201 cgcgacctcc tggttgcggt agaagaagcc gtcgcaggtc gcgcaggccg agacgccgcg
     7261 cccggcgaac ttctcctcgg agggcaggcc gaggtacttg gcggtggcgc cggtggagat
     7321 gatcagcgcg tcgcaggtgt attcgccgct gtcgccgacc aggcggaagg gcttctcgcc
     7381 aagcttcacc gtgtggatgt ggtcgaagat catctcggtg ttgaagcgct cggcgtgctt
     7441 ctggaagcgt gccatcaggt cggggcccat cacgccgtcg gcgtcggccg gccagttgtc
     7501 cacctcggtg gtggtcatga gctggccgcc ctgggcgagg ccggtgatca gcaccgggtt
     7561 caggttggcg cgcgcggcat acacggcggc ggtgtagccg gcggggccgg agccgaggat
     7621 cagcaggcgg gcgtgtttgg tcgtcatgga gtgcggttcc tgcgggtgga ttgcgaggcc
     7681 gcgattatag cggagggggc ggccgcggtt ggcgccgtgc gctccggggc cgggcgggcg
     7741 gcgtgcctgc agggcctcgt gtctgatcgt cgcgggatgt cgaatccgtg aattccgtca
     7801 cgaaatcgag aatgaatggc gggtgatcgt ataaacttga aagtacatgt ttccactgtt
     7861 ccactcctcg tgcctggagc gagcatgacc caagccaccg ccgtttccgt cgtcgccctg
     7921 aagaccttcc cgctgttcca cggcctgtcc gacgattcgc tggccagcat cgcgcgcgtg
     7981 tcgatgatgc gtcgcttccc gcgcgggcag tcggtggtgt gcgcgggcga ccgtcccgat
     8041 tacgtctatc tcgtgctcac cggcagtctc aaggtggtgg tgagcgacga ggacggccga
     8101 gaggtgatcc tgtcgatcct cggccaaggc gagcttttcg gcgagatggg catgttcgac
     8161 gagcgtccgc gctcggcctc ggtgatcgcc gtggtgccgg ccgacctggt gctgatctcc
     8221 aagcaggact tccgccgcat catgcaggac agcttcgacg tgtcctggcg catcatgtgc
     8281 aacctcgccg agcgcctgcg caatgccgac cgcaagatcg agagcctcgc cctgatggac
     8341 gtctacggcc gggtcgcgcg cctgctgatc gagatggcgg aggacgtcgg cggccagtcg
     8401 gtcgtggtcc ggcgcatctc caagcaggat atcgccaaga tgatcggcgc ctcgcgcgag
     8461 atggtgagcc gggtcatgaa ggacctcggc cagcagggcc tgatcgagga aggccccgac
     8521 ggaatcctgt tgcgcgagcg cctcaacgac gtgtgaatcc gcgctcgcct gcgtcgcgtt
     8581 tgtgagcatc cgcaagcgcg gcggcggggc ggggatcgat cccgtataat ccggggtcgt
     8641 tccactctcc ccgcggccgc aacgcaatgc tgtcccgttc gtcctcccgt tcccagccgc
     8701 tgcccgaaaa gatctcgctg ctgctgcagg aagcccgctg gctgatcctc ggcgtggtct
     8761 cgctctacgt cggcatgatc ctcgtcggct acagcgagtc cgacccaggc tggtcgcacg
     8821 cctccgacgt cacccgcgtt gccaatccgg gcgggcgttt cggcgcttgg ctggcggacc
     8881 tcctgctcta tctcttcggc atttcctcgt ggtggtgggt ggtcttcctc ggctacagcc
     8941 tgctgtgggg cttccgccgc ctcaagaacc ggctcgagct cgatcaccgc tccttcatct
     9001 tcgtgatgat cggcttcttc gtcgtgctca tcaccagcag cgcgctcgaa ttcctgcgct
     9061 ttcactccca tggcgcaccg gtgccgctcg agcccggcgg gctgatcggc atggaactcg
     9121 cccagttcgt gcggcgcagc ttcggcttca ccggcggcac gctgctcctg ctcgcgctga
     9181 tggctacggg cctgtcgctg ttcaccgggg tgtcctggct ggcgctgatg gagcgcgtcg
     9241 gcctcgccat cgagcagtcg gtgctcggcg tgcagcaggc ctggctgcgc tggcaggacc
     9301 gccgcgtcgg ccgcgaggtg gcgcacaagc gcgaggaggt ggtgcagacc cggcgcaaga
     9361 aggtcgagaa ggccgagcct gcgcccctgc ggatcgaacc tgcggtagtc gtcgtgccca
     9421 agtccgagcg ggtggagaag gagcgccagc agaccctgtt ccaggacgcg gcggagggcg
     9481 tgatcccgcc ggtggcgctg ctcgatccgg ccagcggcgg cgtggagccg ccctcgccgg
     9541 aggcgctcga attcacctcg cgcctgatcg agaccaagct cgccgacttc ggcgtcgagg
     9601 tcaaggtgct cgctgcctac cccggcccgg tgatcacgcg ctacgagatc gagcccgcca
     9661 cgggcgtcaa gggcagccag gtggtgaacc tcgccaagga tctcgcgcgc gcgctgtcgc
     9721 tggtgtcgat ccgggtggtc gagaccgtgc ccggcaagtc ctgcatggcg ctcgagctgc
     9781 ccaacccgaa gcggcagatg gtgcgcctgt cggagatcat cggttccaag gtgtaccagg
     9841 acgcgcattc gccgctcacc gtggtgctcg gcaaggacat cggtggccag ccggtggtgg
     9901 ccgacctggc caagatgccg cacctgctgg tggcaggtac gaccggctcg ggcaagtcgg
     9961 tcggcatcaa cgccatgatc ctgtcgctgc tctacaagag cgagcccgac cgcgtacgac
    10021 tgatcatggt cgacccgaag atgctcgagc tgtcgatcta cgagggcatc ccgcacctgc
    10081 tcgcgccggt ggtcaccgac atgaagcacg cggccaacgc gctcaactgg tgcgtggccg
    10141 agatggacaa gcgctacaag ctgatggcgg cggtgggcgt gcgcaacctc gccggcttca
    10201 acaaggccgt acaggaggcg cgcaaggccg aggccccgct caccaacccg ttctcgatca
    10261 gcccggagaa cccggagccg ctcgagccct tgccctacat cgtggtggtg gtcgacgagc
    10321 ttgccgacat gatgatggtg gtcggcaaga aggtcgagga gctgatcgcc cgcctcgcac
    10381 agaaggcgcg cgccgccggt atccacctga tcctcgccac ccagcgcccc tcggtggacg
    10441 tgatcaccgg cctgatcaag gccaacgtgc ccacgcgcat cgccttccag gtgtcgagca
    10501 agatcgactc gcgcaccatc ctcgaccaga tgggcgccga gaccctgctc ggcatgggcg
    10561 acatgctcta cctcgcgccc ggtaccgggc tgccggtgcg cgtgcacggt gccttcgtcg
    10621 ccgacgacga ggtgcacaag gtggtcgacc acctcaagaa gatcgg
//
LOCUS       DAOTIN010000114        10276 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_7719_length_10276_cov_10.128950, whole genome shotgun
            sequence.
ACCESSION   DAOTIN010000114 DAOTIN010000000
VERSION     DAOTIN010000114.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 10276)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 10276)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10276
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_7719_length_10276_cov_10.128950"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(275..3556)
                     /locus_tag="P5537_13700"
     CDS             complement(275..3556)
                     /locus_tag="P5537_13700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004318362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HRV79140.1"
                     /translation="MRARLLPGLGFALLYWAVGYPAIHLAIPPGYTAPFFPPAGIALA
                     ALFVFGLRLWPAVFAGSALIQLATAWPLLGSPGWNLLGPLAVPAGATLQAVVGAVLAR
                     RLLAPEDKLDTAGSVMRFLGVCVPLSGLVCSTIGVSALVQAGVIPAADAFFNWWTWWT
                     GDTLGMLVAAPLTLVFIGRPAQDWRPRRLGVALPMSIALVLLALAYQQVVSWENSRLR
                     AQFERDSVHLSGLLQKRLEEQVDMVRSIERLLLASDHVSRSDFHEFVAPWMQRHPGTR
                     SFTWNQHLPHAARTAFEEAMRDEYQTDFRVLDRDAAGQTSPAAERRVYFPVTRVEPED
                     GNRTVLGMDPLSFPISGDAIRRTLADGQPAATARMRLVQAHGEQHAVVLYQAVLASTA
                     DASRREPLGLISAALGMDDLLAAISRQAEEQGIDVRLSDGDAPPEAALLAGDHPAKDS
                     VWPDHALTQVTSIDFAGRHWALETRALPQYTEGLRSWAAWGTIAVGVLASGMLGALLL
                     ITTGNRRRIQALVELRTAELEAAGARLQENRAALVDAQRIARLGSWETLSGRVGLQAS
                     DELRLLLDRSQQRLGSLADLIESIAPASRAALSGAIERAATEPGRIMLDCNTDSLPMR
                     TLQFRIEGEHVDGRLRRIRGTAQDVTALREAETRIRYLARFDPLTGLLNRSAWQDHAQ
                     DVLRHAVRHDDRCAVLFLDLDHFKTVNDSLGHAAGDRLLAQVACRLSGCVREEDLVAR
                     LGGDEFVILLSRLAHTEEPARVAERVLEALARPLQIDGQPLHLGASVGIALYPADGGE
                     IDTLLKHADTAMYEAKESGRNAYRFFLPEMTQRVTRRLQTEAELRRAIEIGELRLHYQ
                     PQVNGATGRVCGCEALVRWQHAERDLLSPDQFIPFAEQSGLIVPLGEWVLREACLQQV
                     RWRDAGLPPLDVAVNISALQFRRRDFVATVARVLAETGADPARIELEITESALMDATP
                     ELVASFDQLVALGLTLALDDFGTGYSSLSYLKRLPLRRLKIDRSFVDGLPDNPEDVAI
                     TSATLSLARDLGMEVVAEGVETEEQRAYLRSRGCGAMQGYLFSRPLGVKAFEEWAWER
                     ATALA"
     gene            3708..5603
                     /locus_tag="P5537_13705"
     CDS             3708..5603
                     /locus_tag="P5537_13705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SurA N-terminal domain-containing protein"
                     /protein_id="HRV79141.1"
                     /translation="MFEAVRNNKRVAQVILAILIVPFAFFGMDAYFSDSGSANEAARV
                     GGTSIGAWEFDQALREQQDRLRQDGGGQVDRALLESAELRRAVLENLINQRVLALYAA
                     ENRLVVTPQQLQETIAGVPSFQENGSFSLQRYENLLRAQGMTPASFEARLAQDVRVQQ
                     IVAAVGDAGIVPQQSARRFLDAQLESRSVREFRLSAKALAADVKVDDAQIKAYYDANP
                     ARFEQPARLQAEYLVFDRAAVERGIAVADDEVRAFYDGNPQRFGVAEERQARHILLAL
                     DQGAEQAEVDRVMAEARALVEALRADPARFAALAKEKSQDPGSAGNGGDLGFFARGMM
                     VGAFEDAVFALDKGAIGEPVRSEFGVHVVQVTDVKPSAVKPFEEVREEIVAELRAQEA
                     GRRFAELAEQFSNTVYEQPDSLQPAAEALGLKTATTDWISRDSAPAALADERVISALF
                     SDEAVQKNRNTEAIEIGNGTLVSARVKAFEPARRLPLEEVRERIVELVRVEQGRVKAA
                     SGGEAMLAALRKGEPAAASWGEVRKLQRGAPGLPAAAMQAVFSAPAGALPAHVGVQSA
                     EGDYVLYRIEAVERAQIGDEDPRVAAVAGQYRQLLAGRDFGAFLSELRQRYEVTINPT
                     ALQVEQR"
     gene            complement(5717..6514)
                     /gene="fabI"
                     /locus_tag="P5537_13710"
     CDS             complement(5717..6514)
                     /gene="fabI"
                     /locus_tag="P5537_13710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004318 - enoyl-[acyl-carrier-protein]
                     reductase (NADH) activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HRV79142.1"
                     /translation="MGFLAGKRILITGLLSNRSIAYGIAKAMHREGAELAFTYQNDRF
                     KDRVAKLAADFGSSLIYPLDVQDDAQITGLFEQLGQQWDGLDGLVHSIAFAPGEALEG
                     DFLDGLTREAFRISQEVSTYSFPALVKAARPLMQGRNASVLTLSYLGAVRTMPNYNIM
                     GLAKASLEASVRYLAVTLGPEGIRANAISAGPIKTLAASGIGSFGKLLAFNEHNAPLR
                     RNVTIEEVGNAAAFLCSDLASGVTGEVMYVDGGFNTTALGNALPLPQ"
     gene            6835..9066
                     /locus_tag="P5537_13715"
     CDS             6835..9066
                     /locus_tag="P5537_13715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HRV79143.1"
                     /translation="MRATGAALAAGLAVAGCGPVWNDPYPAAERGEHILYTAFTERPK
                     HLDPVQSYSEDEASFLYQIVEPPLQYHYLKRPYVLEPATAEAMPRLRRLDAGGRELPP
                     NADPAKVVRTVVEVRIRPGILYQPHPAFALDEAGSPRYLGLGEADLGGVRGLGDFAVT
                     GTRELEARDYVYQIKRLAHPRLHSPIFELMAEYLPGLKDLQAALAAADAADAAQGGGD
                     GPPGWLDLDRFDLSGVEVVDRHTWRISLQGAYPQFLYWLSMPFFSPVPREVDRFFAQP
                     GMAERNLTLDWWPVGTGPYMLVENNPNARMVLARNPNYRGDPYPCAGEPGDAEAGLLA
                     DCGKPMPFIDKVVFSREREGIPYWNKFLQGYYDASGVSSDNFDQAVSLTSQGEVTLSD
                     DMRDKGIRLLTSVSPSIFYLGFNMLDPLVGGGASKADKERARKLRQAISIALDMEEFV
                     SIFLNGRGLPGMSPLPPGIFGAREGRAGMNPVVYEWQGGDADGRPLRRGVDAARRLLA
                     EAGWPNGRNAQTGEPLVINLDTTPGGLGDKARSDWLAKKFRDLGVQFVVRPTDFNRFQ
                     DKIRQGNAQLFFFGWNADYPDPENLLFLLHGAQGKVKFNGQNAANYENPEYDALFERM
                     KAMPDGAARQQLIDRMVAMLQQDAPWIFAFHPMSYSLQHGWVLNRKTGAMVRNTMKYQ
                     RIDLERRAAARAAWNEPVTWPLLLVAALLAALVAPAAIHWRRRETATAAPSAAGPGAG
                     GGR"
     gene            9066..10043
                     /locus_tag="P5537_13720"
     CDS             9066..10043
                     /locus_tag="P5537_13720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018990170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV79144.1"
                     /translation="MLAYLLRRLLYAVPILIGVNLLTFVLFFVVNSPDDMARMHIGVK
                     RATPEAIERWKAERGYDRPMFLNDAASGSARFTETIFFDKSLRMFALEFGRADDGRDI
                     GQEIRDRMGPSLAIALPTFLLSLAVSISFALLLVFFRATYLDFWGVVLCVAMMSISSL
                     FYIIGGQWLVSKLWALVPISGYAPGLDAARFLVLPVLISVIAGIGSSARWYRTIFLEE
                     ISKDYVRTARAKGLSELAVLFRHVLRNALIPILTGVVVVIPLLFMGSLLVESFFAIPG
                     LGSYTIDAINAQDFAVVRAMVFIGSVLYIVGLMLTDLSYTLADPRVRLQ"
     gene            10040..>10276
                     /locus_tag="P5537_13725"
     CDS             10040..>10276
                     /locus_tag="P5537_13725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV79145.1"
                     /translation="MSTSSGILGFQPVVLWTDALLFVLVALALLSALRARTQAPLRAA
                     WRKVGRRPAGMAAATVLLAFLAVGLVDSLHYRPLL"
BASE COUNT         1502 a         3483 c         3725 g         1566 t
ORIGIN      
        1 ccggcgctcc tacataaacc gccgcgcatc ccggccgccc ctgtaggagc tgcggcagct
       61 gcgaacatgg cggtcggggt atcgacgcgc gtcgccttcg gtcggcgccg ctttcgcgcc
      121 tgccggcgct cctacacgaa ccgccgcgtg tccgggccgc gctgtaggag ctgcggaagc
      181 tgcgaacacg gcagtcgggg tatcgacgcg cgttgccttc ggtcggcgcc gtcttcgcgc
      241 ctgccggcgc tcccacatag gcgcggcggg ctcgtcaggc gagcgcggtt gcacgctccc
      301 aggcccactc ctcgaacgcc ttcaccccca gcggccgcga gaacaggtaa ccctgcatcg
      361 caccacaccc ccggctgcgc aggtaggcgc gctgctcctc ggtctccacc ccctcggcga
      421 ccacttccat gcccaggtcg cgggcgagcg agagtgtggc cgaggtgatc gccacgtcct
      481 ccgggttgtc cggcaagccg tcgacgaagg agcggtcgat cttgagccgg cgcagcggca
      541 ggcgcttcag gtaggacagg ctggaatagc cggtaccgaa atcgtccagg gccagcgtca
      601 acccgagcgc cacgagctgg tcgaagctcg cgaccagctc gggcgtcgcg tccatcagcg
      661 cgctttcggt gatctccagc tcgatccgcg cggggtcggc gccggtctcg gcgagcacgc
      721 gcgccaccgt ggcgacgaag tcccgccggc ggaactgcag cgcggaaatg ttcaccgcga
      781 cgtccagcgg cggcaggccc gcgtcgcgcc agcgcacctg ctgcaggcag gcctcgcgaa
      841 gcacccattc gccgagcggc acgatcagcc cgctctgctc ggcgaagggg atgaactggt
      901 cgggcgagag caggtcgcgt tctgcgtgct gccagcgcac cagcgcctcg cacccgcaga
      961 cccggccggt cgcgccgttg acctggggct ggtagtgcag acgcaactcg ccgatctcga
     1021 tcgcgcgtcg aagctcggcc tcggtttgca ggcggcgggt gacgcgctgg gtcatctcgg
     1081 ggaggaagaa gcgataggcg ttgcgcccgg actccttggc ctcgtacatc gccgtgtcgg
     1141 catgcttgag cagcgtgtcg atctcgccgc cgtcggccgg gtagagcgcg atgccgacgc
     1201 tcgcgccgag atgcagcggc tggccgtcga tctgcagcgg ccgggcgagc gcttccagga
     1261 cgcgttcggc cacgcgtgcc ggctcttcgg tgtgtgcaag gcgcgacagc aggatcacga
     1321 attcgtcgcc gccgaggcgg gcgaccaggt cttcctcgcg cacgcagccg ctcaggcggc
     1381 aggccacctg ggcgagcaga cggtcgccgg cggcgtggcc gagcgaatcg ttgaccgtct
     1441 tgaagtggtc gaggtcgagg aacagcaccg cgcagcggtc gtcatgacgc accgcgtggc
     1501 gcagcacgtc ctgggcgtgg tcttgccagg cgctgcggtt gagcagcccg gtgagcgggt
     1561 cgaagcgggc gaggtagcgg atgcgcgtct cggcttcgcg cagcgcggtg acgtcctgcg
     1621 cggtgccgcg gatgcggcgc aggcggccgt cgacatgctc gccttcgatg cggaactgca
     1681 gggtccgcat cggcaggctg tcggtattgc agtcgagcat gatccggccc ggctcggtgg
     1741 cggcacgctc gatcgcgccg ctcagcgcgg cgcggctggc cggcgcgatc gattcgatca
     1801 ggtcggcgag cgagccgagc cgctgttggc tgcggtcgag caggaggcgg agctcgtccg
     1861 aggcttgcag gccgacgcgc cctgagagcg tctcccagct gcccaggcgg gcgatgcgct
     1921 gcgcgtcgac cagtgcggcg cggttctctt gcaggcgcgc acccgcggcc tcgagctcgg
     1981 cggtgcgaag ctcgaccagg gcctggatgc ggcggcggtt gcccgtggtg atcagcaaca
     2041 gcgcaccgag catgccgctg gcgagtacac cgactgcgat cgtgccccag gccgcccagc
     2101 tgcgcaggcc ctcggtgtat tggggcaagg cacgggtttc cagcgcccag tggcgaccgg
     2161 cgaaatcgat ggaagtgacc tgcgtcagtg cgtggtccgg ccagaccgaa tccttcgcgg
     2221 ggtggtcgcc ggcgagcagg gccgcttcgg gcggggcgtc gccatcggag aggcggacgt
     2281 cgatgccttg ctcctctgcc tggcgcgata tcgcagcgag caggtcgtcc atgcccagtg
     2341 ccgcggagat gaggccgagc ggttcgcggc gggatgcgtc cgcggtggag gcgagcacgg
     2401 cctggtagag cacgacggcg tgctgctccc catgcgcctg cacgagtcgc atgcgggcgg
     2461 tggcggcggg ttgaccgtcg gcgagtgtgc gccggatcgc gtcgccggag atcgggaagg
     2521 agagcgggtc catgcccagc accgtgcggt tgccgtcctc gggctcgacg cgggtgaccg
     2581 ggaagtacac ccgacgctcg gcggcaggcg aggtctgtcc ggcggcgtcg cggtcgagga
     2641 cgcggaaatc cgtctggtac tcgtcgcgca tcgcctcctc gaacgcggtg cgtgcggcgt
     2701 gcggcaggtg ctggttccag gtgaagctgc gcgtgccggg gtggcgttgc atccatggcg
     2761 cgacgaactc gtggaagtcg ctgcgcgaga cgtgatcgct cgcgagcagc aggcgctcga
     2821 tcgagcgcac catgtcgacc tgctcttcga ggcgtttctg cagcaggccc gagaggtgga
     2881 cgctgtcgcg ctcgaactgc gcgcgcagcc gcgagttctc ccagctcacg acctgctggt
     2941 aggccagcgc gagcagcacg agtgcgatcg acatcggcag tgcgacgccg agccggcgcg
     3001 ggcgccagtc ctgcgccggg cggccgatga agaccagggt cagcggcgcg gcgacgagca
     3061 tgcccagggt gtcgccggtc caccaggtcc accagttgaa gaatgcatcg gctgccggga
     3121 tgacacccgc ctggaccagc gcggagacgc cgatcgtcga gcagaccagg ccgctcagcg
     3181 gcacgcagac gcccaggaag cgcatcaccg agccggccgt atcgagcttg tcttcggggg
     3241 cgagcagccg gcgcgcgagc actgcgccga cgactgcctg cagcgtggcg cctgccggga
     3301 cggcgagcgg gccgagcagg ttccagcccg ggctgccgag cagcggccag gcggtggcga
     3361 gctggatcag cgccgagccg gcgaacaccg ccggccacag gcgcagcccg aacacgaaca
     3421 gcgccgcgag cgcgatgccg gctggcggaa agaatggagc ggtatacccc ggcgggatgg
     3481 cgaggtggat cgcggggtag cccaccgccc aatagagcag ggcgaatccg agtccgggga
     3541 gaaggcgagc gcgcatccgc gcagtatatt gagagtagtt cgcaccccgg tgtgacggat
     3601 ggcatgctgc ggacccgaag ccggggcatt gcgctaaact gcggaacttt cgcgccggcg
     3661 cccgttccac cgtgctgcgc ttcattgtcc tttccacgga atacgagatg ttcgaggctg
     3721 ttcgcaacaa caaacgcgtc gcgcaggtga tcctggcgat cctgatcgtc cccttcgcct
     3781 tcttcggaat ggacgcctac ttcagcgact ccggttccgc gaacgaggcg gcgcgcgtcg
     3841 gcggcaccag catcggcgcg tgggagttcg accaggccct gcgcgaacag caggaccgcc
     3901 tgcgccagga cggcggtggc caggtcgacc gcgcgctcct ggagtcggcc gagttgcgcc
     3961 gcgcggtgct ggagaacctg atcaaccagc gcgtgctcgc cctctacgcc gccgaaaacc
     4021 gcctcgtggt gacgccgcag caactgcagg agaccatcgc cggcgtgccg tccttccagg
     4081 agaacggcag cttctcgctg cagcgctacg agaacctgct gcgcgcccag ggcatgacgc
     4141 ccgccagctt cgaggcgcgc ctggcgcagg acgtgcgggt gcagcagatc gtcgcggcgg
     4201 tgggcgatgc cggcatcgtc ccgcagcagt cggcgcggcg cttcctcgat gcccagctcg
     4261 agtcgcgcag cgtgcgcgag ttccgcctct cggcgaaggc gctggcggcg gacgtcaagg
     4321 tcgacgacgc gcagatcaag gcctactacg acgccaaccc ggcgcgcttc gagcagcctg
     4381 cgcggctgca ggccgaatac ctcgtcttcg accgcgcggc ggtcgagcgt ggcatcgcgg
     4441 tcgcggacga cgaggtgcgg gcgttctacg acggcaaccc gcagcgcttc ggcgtggccg
     4501 aggagcgcca ggcgcgccac atcctgctcg ccctcgacca aggggccgag caggccgagg
     4561 tcgatcgcgt gatggccgag gcgcgtgcgc tcgtcgaagc gctgcgtgcc gacccggcgc
     4621 gcttcgccgc gctggcgaag gagaagtcgc aggaccccgg ctcggccggc aatggcggcg
     4681 atctcggctt cttcgcccgc ggcatgatgg tcggcgcctt cgaggatgcg gtgttcgcac
     4741 tggacaaggg cgcgatcggc gagcccgtgc gcagcgagtt cggcgtgcat gtcgtccagg
     4801 tcaccgacgt caagccatcc gcagtgaagc ccttcgagga ggtgcgcgag gagatcgtcg
     4861 ccgagctgcg cgcccaggag gccggccgtc gtttcgccga gctggccgaa cagttctcca
     4921 acacggtcta cgagcagccc gacagcctgc agcctgccgc cgaggcgctc ggcctgaaga
     4981 ccgccaccac cgactggatc agtcgcgact ccgcccccgc ggcgctcgct gacgagcgcg
     5041 tgatctctgc cctgttcagc gacgaggcgg tgcagaagaa ccgcaacacc gaggccatcg
     5101 agatcggcaa cggcaccctg gtttcggcgc gggtcaaggc cttcgagccg gcgcgccggc
     5161 tgccgctgga agaggtgcgc gagcgcatcg tcgagctcgt ccgcgtcgag cagggccggg
     5221 tgaaggccgc gagcgggggc gaggcgatgc tggccgcgct gcgcaagggc gagccggcgg
     5281 cggccagctg gggggaggtg cgcaagctgc agcgcggcgc ccccgggttg ccggcggcgg
     5341 cgatgcaggc ggtgttctcg gcccccgccg gggccctgcc ggcgcacgtc ggcgtgcagt
     5401 ccgccgaggg cgactacgtg ctgtaccgta tcgaggcggt cgagcgtgcg cagatcggcg
     5461 acgaggatcc gcgcgtcgcc gcggtggccg ggcagtaccg gcagctgctt gccgggcgcg
     5521 acttcggcgc cttcctgagc gagctgcgcc agcgctacga ggtgacgatc aacccgaccg
     5581 cgctgcaggt cgagcagcgc tgatcccctt cggcatccgc cctgtcgccg ttgcggcgag
     5641 ggcggcacgg aaacgcaaaa gcccggtttc gagaccgggc ttttgcgttt ccgcctgctg
     5701 caggcgggcg gcggccttat tgcggcagcg gcagcgcgtt gccgagtgcg gtggtgttga
     5761 agccgccgtc cacatacatc acctcgccgg tgacgccgct ggcgagatcc gagcacagga
     5821 aggcggcagc gttgccgact tcctcgatgg tcacgttgcg gcgcagcggg gcgttgtgct
     5881 cattgaacgc gagcagcttg ccgaagctgc cgatgccgga cgccgcgagc gtcttgatcg
     5941 ggccggcgga gatcgcgttg gcgcggatgc cttccgggcc gagggtgacg gcgaggtagc
     6001 gcaccgacgc ctccaggctg gccttggcga gccccatgat gttgtagttg ggcatggtgc
     6061 gcacggcgcc gagataggac agtgtcagca cgctggcgtt gcggccctgc atcagcgggc
     6121 gcgcggcctt caccagcgcc gggaagctgt aggtgctgac ctcctgcgag atgcggaagg
     6181 cctcgcgggt gaggccgtcg aggaagtcgc cctcgagcgc ctcgccgggt gcgaacgcga
     6241 tcgaatgcac cagcccgtcg agaccgtccc actgctggcc gagttgctcg aagaggccgg
     6301 tgatctgcgc gtcgtcctgc acgtcgagcg ggtagatcag gctgctgccg aagtcggcgg
     6361 cgagcttggc gacgcggtcc ttgaagcggt cgttctgata ggtgaaggcg agctcggcgc
     6421 cttcgcggtg catggccttg gcgatgccgt aggcaatcga acggttgctg agcagaccgg
     6481 tgatgaggat tcgtttgccg gcgagaaagc ccatgagaga tgactccgaa tgacaagacg
     6541 gcgattatag cgaaaaaccg tcaaaaccct gcgagggaca ggactttccg caccgtggtg
     6601 gaacgaaggg cgggcggtgg agcgggttct gcggggggct gccgcggcgc tgcggctgga
     6661 gttcggctgc cggtccggcg ccgcgcgcgg atcgcaagcg cgtgcgaaac ctgccagaat
     6721 ccgcgcttcg atcaaagctc ctgcctgccc gtgcgccggt tctccagtcc tctccggatc
     6781 ctcgcccaag cccgcccgag cccgtctgcg catctgcgca gggcggccgc atgcttgcgc
     6841 gcaacggggg ccgcgctggc cgcagggctg gcggtggccg gctgcgggcc ggtctggaac
     6901 gacccctatc cggcggccga gcgcggcgag cacatcctgt ataccgcctt caccgagcgt
     6961 cccaagcatc tcgatccggt gcagtcctat agcgaggacg aggcgagctt cctgtaccag
     7021 atcgtcgagc cgccgctgca gtaccactac ctgaagcgcc cctatgtgct cgaaccggca
     7081 accgccgagg ccatgccgcg gctgcgccgg ctcgacgccg gcggacgtga attgccgccg
     7141 aatgccgacc cggccaaggt ggtccggacc gtggtcgagg tgcgcatccg cccgggcatc
     7201 ctgtaccagc cgcacccggc gttcgcgctc gacgaagccg gcagcccgcg ctacctcggc
     7261 ctcggcgagg ccgacctggg cggcgtgcgc ggcctcggcg acttcgccgt gaccggcacg
     7321 cgcgagctcg aggcgcgcga ctacgtctac cagatcaagc gcctggcgca tccgcgcctg
     7381 cattcgccga tcttcgagct gatggcggag tacctccccg ggctcaagga cttgcaggcg
     7441 gcgctggccg cggccgatgc ggcggacgcg gcgcagggag gcggggacgg gccgcccggc
     7501 tggctggatc tggaccgttt cgacctgtcg ggcgtcgagg tggtggaccg ccacacctgg
     7561 cgcatcagcc tgcagggcgc ctatccgcag ttcctgtact ggctgtcgat gcctttcttc
     7621 agcccggtgc cgcgcgaggt ggaccgcttc ttcgcccagc ccggcatggc cgagcgcaac
     7681 ctcacgctcg actggtggcc ggtgggcacc gggccctaca tgctggtcga gaacaatccc
     7741 aacgcgcgca tggtgctggc gcgcaacccg aactaccgcg gcgaccccta tccctgcgcc
     7801 ggagagcccg gtgacgccga ggccgggctg ctcgccgact gcggcaagcc catgcccttc
     7861 atcgacaagg tggtgttctc gcgcgagcgc gagggcattc cctactggaa caagttcctg
     7921 cagggctact acgacgcctc cggggtgtcc tcggacaact tcgaccaggc cgtcagcctc
     7981 accagccagg gcgaggtcac gctgtcggac gacatgcgcg acaagggcat ccgcctgctc
     8041 acctcggtgt cgccgtcgat cttctacctc ggcttcaaca tgctcgaccc gctggtgggt
     8101 ggcggcgcgt cgaaggcgga caaggagcgc gcgcgcaagc tgcgccaggc gatctcgatc
     8161 gcgctcgaca tggaggagtt cgtgtcgatc ttcctcaacg gccgcggcct gccggggatg
     8221 agcccgctgc cgccgggcat cttcggtgcg cgcgaggggc gggcggggat gaacccggtg
     8281 gtctatgaat ggcagggcgg cgacgcggac gggcgcccgc tgcgccgtgg cgtcgacgcg
     8341 gcgcgccgcc tgctcgccga ggccggctgg cccaacgggc gcaacgcgca gaccggcgag
     8401 ccgctggtga tcaacctcga caccacgccc ggcgggctgg gcgacaaggc gcgctcggac
     8461 tggctggcga agaagtttcg cgatctgggc gtgcagttcg tggtgcgccc gaccgacttc
     8521 aatcgcttcc aggacaagat ccgccaaggc aacgcgcagc tcttcttctt cggctggaac
     8581 gccgactatc ccgatcccga gaacctgctc ttcctgctcc acggtgcgca gggcaaggtg
     8641 aagttcaacg gccagaacgc ggccaactac gagaacccgg aatacgacgc cctcttcgag
     8701 cgcatgaagg ccatgcccga cggagccgcg cgccagcagc tcatcgaccg catggtggcg
     8761 atgctgcagc aggacgcgcc gtggatcttc gccttccacc ccatgtcgta ttcgctgcag
     8821 cacggctggg tgctgaaccg caagaccggc gccatggtgc gcaacaccat gaagtaccag
     8881 cgcatcgacc tcgagcgtcg cgccgccgcg cgcgcggcgt ggaacgagcc ggtgacctgg
     8941 ccgctgctgc tggtagcggc gctgctcgcc gcgctggtgg cgccggcggc gatccactgg
     9001 cgtcggcgcg agaccgccac cgcggcgccg agcgcggccg ggcccggcgc gggaggaggg
     9061 cgctgatgct ggcctacctg ctgcgccgcc tgctgtacgc ggtgccgatt ctgatcgggg
     9121 tgaatctgct caccttcgtg ctcttcttcg tggtgaactc ccccgacgac atggcgcgca
     9181 tgcacatcgg cgtcaagcgt gcgacgcccg aggccatcga gcgctggaag gccgagcgcg
     9241 gctacgacag gccgatgttc ctcaacgacg ccgcgagcgg cagtgcgcgc ttcaccgaga
     9301 ccatcttctt cgacaagtcg ctgcgcatgt tcgcgctcga gttcggccgc gccgacgacg
     9361 gccgcgacat cggccaggag atccgcgacc gcatggggcc gtcgctggcg atcgcgctgc
     9421 cgaccttcct gctcagcctc gcggtgtcga tcagcttcgc gctgctgctg gtgttcttcc
     9481 gcgccaccta cctggatttc tggggcgtgg tgctgtgcgt ggcgatgatg tcgatctcga
     9541 gcctgttcta catcatcggc gggcagtggc tggtctccaa gctgtgggcg ctggtgccga
     9601 tctcgggcta tgcgccgggg ctggacgcgg cgcgcttcct cgtgctgccg gtgctgatca
     9661 gcgtgatcgc gggcatcggc tcgtcggcgc gctggtaccg cacgatcttc ctcgaggaga
     9721 tctcgaagga ctacgtgcgc accgcgcgcg ccaagggcct gtccgagctt gcggtgctgt
     9781 tccgccacgt gttgcgcaac gcgttgatcc cgatcctcac cggggtggtg gtggtgatcc
     9841 cgctgctctt catgggcagc ctgctggtgg agtccttctt cgcgatcccc ggactgggca
     9901 gctacaccat cgacgcgatc aacgcgcagg acttcgcggt ggtgcgcgcg atggtgttca
     9961 tcggctcggt gctctacatc gtgggactga tgctcaccga cctgtcctac accctggccg
    10021 atccgcgggt gaggctgcaa tgagcacatc gagcgggatc ctcggcttcc agccggtcgt
    10081 gctatggacc gacgcgctgc tcttcgtgct cgtcgcgctg gcgctgctct cggccttgcg
    10141 cgcccgtacg caggcgccgc tgcgcgcggc ctggcgcaag gtcgggcggc ggccggccgg
    10201 gatggcggcg gccaccgtgc tgctcgcctt cctggccgtc ggcctggtcg acagcctgca
    10261 ttaccggccg ctgctg
//
LOCUS       DAOTIN010000115        10244 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_7761_length_10244_cov_9.100991, whole genome shotgun sequence.
ACCESSION   DAOTIN010000115 DAOTIN010000000
VERSION     DAOTIN010000115.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 10244)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 10244)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10244
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_7761_length_10244_cov_9.100991"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(521..1843)
                     /gene="chrA"
                     /locus_tag="P5537_13730"
     CDS             complement(521..1843)
                     /gene="chrA"
                     /locus_tag="P5537_13730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015109 - chromate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015703 - chromate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromate efflux transporter"
                     /protein_id="HRV79146.1"
                     /translation="MNEAKHTEHSPWAVFLIFLRLGLTSFGGPVAHLGYFHAEFVARR
                     RWLDERAYADLVALCQFLPGPASSQVGMALGLRRAGYRGALAAWAGFTLPSAIVLILF
                     ALGLARHGDALPPGVLHGLKVVAVAVVAQAVWGMAGKLCTDRARIGLMALAACVVLAL
                     PTAWSQVGVIALAGLAGMVLFRAQAEGGGSEPTAATRGAASSGARAGTLDPRSSVSVP
                     PAGVSDPDSVALRPNTGAPGPRSGWLWLVAFFALLAGLPLLAALQPDGWLARVDAFYR
                     SGALVFGGGHVVLPLLQAEVVPTGWVDGEAFLAGYGAAQAVPGPLFTFAAFLGAAAQG
                     GYGGWLGGVVCLLAVFAPSFLLVAGALPFWERLRGDARMQAALAGINAAVVGLLLAAL
                     YQPVWTSAIHRPQDFALGLVALVALMSWKWPPWLVVAACGVAGGVLGV"
     gene            complement(1989..2930)
                     /locus_tag="P5537_13735"
     CDS             complement(1989..2930)
                     /locus_tag="P5537_13735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HRV79147.1"
                     /translation="MSDKPSMNGDDHAAGGCCGQCGGAVPRPRLQRLATGAGPAVRLG
                     SAAARTRSVFRIPGMDCPSEEQMIRLRLADAAVAALAFDLAGRRLTVDHDGDPQAILA
                     RLVPLGYGAELAESRALAAGEMQSAAPGDDAAEARVLWTLLAINASMFVVELGAGLWA
                     RSAGLIADAMDMFADAAVYGVALYAVGRAARHKLAAARLAGVLQLVLALGALAEVVRR
                     MLAGAMPEPVGMMGIALLALAANVACLVLIARHREGGVHMKASYIFSANDVIANLGVI
                     GAGALVAWLGTPWPDWIIGLLIAVVVLAGAVRILRLR"
     gene            complement(2941..3375)
                     /locus_tag="P5537_13740"
     CDS             complement(2941..3375)
                     /locus_tag="P5537_13740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemerythrin family protein"
                     /protein_id="HRV79148.1"
                     /translation="MPIFWRPQFRIGQDDIDADHRYLILLINTVELVLRFPDDPRNVD
                     LALIELRRYAEYHFEREERIQIAYGYLHLDQHKREHRALLAEIDILAQRIHATLEDPD
                     GGVEGIKAQSGEITAFLRKWLVDHVMKADMLLVPLFRKPVVR"
     gene            complement(3450..4079)
                     /locus_tag="P5537_13745"
     CDS             complement(3450..4079)
                     /locus_tag="P5537_13745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF938 domain-containing protein"
                     /protein_id="HRV79149.1"
                     /translation="MSPFDRRQFSPSAARNRDPILAVLQRVLPSAGLVLELGSGTGEH
                     AVHFARHLSALRWQPSEADPAALASITDWVVHAALPNVLPPLCFDLAATPWPVAAADA
                     VVAINVLHYSPWPTTPALFAGAAEVLPAGGVVVCYGPYRRGSAHTAPSNAEFDEWLRS
                     IDARFAVRDLETVEAEAQRCGFVLEEVVGMPANNLSLVFRRGAGCDAVA"
     gene            4205..5404
                     /locus_tag="P5537_13750"
     CDS             4205..5404
                     /locus_tag="P5537_13750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CaiB/BaiF CoA-transferase family protein"
                     /protein_id="HRV79150.1"
                     /translation="MTTPTKPLAGIKVVELGTLIAGPFAARILAEFGAEVIKIESPDG
                     GDPLRKWRKLYEGTSLWWYLQARNKKSVTVNLKHPDGVEVVRRLVAEADIVVENFRPG
                     VLDKLGLGWEALSKINSGLVMVRLSGFGQSGPMAQQPGFGAIGESMGGLRYVTGFPDR
                     PPVKTGISIGDSIAALWGALGALMALRHKEVNGGAGQVVDVALYEAVFAMMESLVPEF
                     DVFGFVRERTGNIMPGITPSNTHTTRDGRHITIGANGDAIFRRLMRAMGREDLAEDPT
                     LADNAGRDARRDELYALIDAWVAQHDEAAVLATLAAAEVPASRIYSVADMFADPQFLA
                     REMLHTVTLPDGRDCRMPGVVPRLSATPGGSEWIGPALGEHTDAVLAGLGYDEARIAA
                     LRAAGAI"
     gene            complement(5535..6719)
                     /locus_tag="P5537_13755"
     CDS             complement(5535..6719)
                     /locus_tag="P5537_13755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0042908 - xenobiotic transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bcr/CflA family efflux MFS transporter"
                     /protein_id="HRV79151.1"
                     /translation="MSTAFIVLVLSLLLGLQPVTTDLYLPALPALTQDLGATVAQAQL
                     TLSGLLLAFGLSQLVWGPISDRFGRRPVLLLGLATYVVGAVGGALAGSMEALLLWRIV
                     QGAALGASVMCARALVRDLYSPELGARAISKGLTGLGVIACLSIPLGGVLAEFFGWRI
                     ALSAPALFGAATLALIALRFEETLQRPDPDALRPGTLVRTWLAILRNPTFLAFALLAA
                     ATYGGLFTLLAASSFVFIRLMELSRIEYAALMFVIVLAYVGGTLLCRRLLVRFGVQRT
                     VAIGGVFSLLGGSLLGLGGMAGLEGVWPILLPMLIYMLGHGIHQPCGQAGAVGPFPKA
                     AGAASAMSGFVMMVVAFAMGQWLGASMDGTSLPMIHGVWFWSVATAAVAWGLVGRVPR
                     QA"
     gene            complement(6886..7530)
                     /gene="maiA"
                     /locus_tag="P5537_13760"
     CDS             complement(6886..7530)
                     /gene="maiA"
                     /locus_tag="P5537_13760"
                     /EC_number="5.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016034 - maleylacetoacetate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006559 - L-phenylalanine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="maleylacetoacetate isomerase"
                     /protein_id="HRV79152.1"
                     /translation="MKLHTYFRSSAAYRVRIALHLKGLDYEAVPVHLVRGGGEHRQPA
                     YLGLNPAGLVPALEDAGQVLTQSLAIVEYLEETHPQPALLPAAALDRARVRAIAQAIA
                     CDIHPVNNLRVLQYLTRELGASEAQKNAWYRHWIGVGLQAVEAMLAGDARTGAFCHGD
                     TPGLADCCLVPQVFNARRFGCELSAMPTVLRIADRCAGLEAFRRAAPEAQPDAE"
     gene            complement(7535..8545)
                     /locus_tag="P5537_13765"
     CDS             complement(7535..8545)
                     /locus_tag="P5537_13765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HRV79153.1"
                     /translation="MKLATLKQGGRDGTLVVVSRDLARCRAVPAIARSLQAALDDWQA
                     CEPQLRQVYEALNSGAVDAQPFDQAACASPLPRAYQWADGSAYINHVELVRKARNAEM
                     PPSFYTDPLMYQGGSDSFIGPRDAVVADEAWGIDFEAEVTVVTGDVPMGATPAEAAKA
                     IRLVMLVNDVSLRNLIPNELAKGFGFFQSKPASAFSPVAVTPDELGDAWQDAKVHLPL
                     VVHLNDKLFGKPEAGVDMTFDFGQLVAHVAKTRELEAGSIIGSGTVSNKQGDLWGSSI
                     DHGGVGYCCLAEVRTYETIEQGKPATPFMRDGDVVRIEMFDRQGASVFGTIENRVAAR
                     KG"
     gene            complement(8542..9093)
                     /locus_tag="P5537_13770"
     CDS             complement(8542..9093)
                     /locus_tag="P5537_13770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HRV79154.1"
                     /translation="MTPIVKKIHHVAYRCKDALETARWYEKHLGMKLVLSIAEDAVPS
                     TGEPDPYMHIFMDAGMGNVLAFFELPTRAPMGRDENTPAWTQHLALEVDSMETLLAAK
                     ARLESAGIQVVGPTDHALFQSIYFFDPNGHRLELACNTNRPGMLEALDKVKWDMLEEW
                     AQTKKAPKHAAWMHDGSYKEMFQ"
     gene            complement(9246..9482)
                     /locus_tag="P5537_13775"
     CDS             complement(9246..9482)
                     /locus_tag="P5537_13775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2783 domain-containing protein"
                     /protein_id="HRV79155.1"
                     /translation="MALNTQPNLFEPGKRYFRAFSPGDDFYEALIETHRELSDEQSEM
                     VNARLILLLANHIGDISVLREAMSIARAGVASKD"
     gene            complement(9494..>10244)
                     /locus_tag="P5537_13780"
     CDS             complement(9494..>10244)
                     /locus_tag="P5537_13780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002930464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="FAD-dependent monooxygenase"
                     /protein_id="HRV79156.1"
                     /translation="GDSAHQVSPFGARGANSGIQDADNLVWKLALVMDGKAPATLLDT
                     YGDERGFAADENIMNSTRSTDFITPKSRTSKTFRNAVLGLAEHHAFARALVNSGRLSV
                     PSFLVGSRLNTADDAVFAGNMVPGAPMDDAPIATADGESWLLQVLGDRFQVLHYVADA
                     ADLDAASVAALQSLAEGAIPVEPIVVAARGQAPAGLRTLTDAKGRIRERYDLQPGTTY
                     LVRPDQHVTARWRALDPARVRAAVARATCNA"
BASE COUNT         1591 a         3717 c         3626 g         1310 t
ORIGIN      
        1 cgggagtgcc ggactacctc aagcgcatgc tggacgagga agacaagggc tgagaagacg
       61 gccgcgagct cgtctgcgcc ggccggttgc caccctccgc cgggcggaac cgcctgcgcc
      121 gcttcaccac cgaattcgcg gctgccgccg ctcctgcatc cacccccacc ccggcgacgt
      181 ttctccttag gagcgccggc aggcgcaccc cctccgaaaa cgcaacgcct catgtaggag
      241 cgccggcagg cgcgaaccaa cctctccgaa gacgtaacgc ttcatgtagg aatgccggca
      301 ggcgccaatc gggcgctgca gccgccgccg gcgtggccgc atgtcggcaa ggccgcattc
      361 gcgcctgccg gcgctcctac aggaaccggc gcggctccga tctgcatgcg aagcgccggc
      421 aggcgcgaac tgcaggagac ccgccccgcg cgccctcctc cgaaaccgcg acgcctcatg
      481 taggagcgcc ggcaggcgcg aaccgccctt cccgcccgcg ctacaccccc agcaccccgc
      541 ccgccacccc gcacgcggcc accaccagcc agggcggcca cttccacgac atcagcgcga
      601 ccagcgccac gaggccgagc gcgaaatcct gcgggcggtg gatcgcgctg gtccacaccg
      661 gctggtacag cgccgccagc aacagcccca ccaccgccgc gttgatgccg gcgagcgcgg
      721 cctgcatgcg cgcgtcgcca cgcaggcgct cccagaacgg cagcgcaccc gccaccagca
      781 ggaaggacgg cgcgaacacg gcgagcaggc acacgacgcc gcccagccaa cccccgtagc
      841 ccccctgcgc cgcggcaccg aggaaggcgg cgaaggtgaa cagcggcccc ggcaccgcct
      901 gcgccgcacc atagccggcg agaaaggcct cgccgtccac ccagccggtc ggcaccacct
      961 cggcctgcag cagcggcagc accacatggc cgccgccgaa caccagcgcg cccgaacggt
     1021 agaaggcatc cacgcgcgca agccagccat cgggctgcag cgcagcgagc agcggcaggc
     1081 cggcgagcag cgcgaagaag gctacgagcc acagccaccc cgagcgcggc cccggtgcac
     1141 ccgtattcgg ccgcagggcc accgagtccg gatcggatac tcccgcaggt ggcaccgaca
     1201 cactcgagcg cggatcgagc gtgcccgcac gcgctcccga ggaagccgcg ccccgcgtcg
     1261 ccgccgtggg ttcgctgccc ccgccctccg cctgcgcgcg gaacagcacc atcccggcca
     1321 gccccgcgag cgcgatcacc cccacctgcg accacgccgt cggcagcgcc agcaccacgc
     1381 aggccgcgag cgccatcagg ccgatgcgcg cgcggtcggt gcacagcttg cccgccatgc
     1441 cccacaccgc ctgcgccacc accgccaccg ccaccacctt gagcccgtgc agcacgccgg
     1501 gcggcagcgc gtcgccatgg cgcgcgaggc cgagcgcgaa gaggatcagc acgatcgccg
     1561 agggcagcgt gaagcccgcc cacgccgcca gcgccccacg atacccggcg cgccgcagcc
     1621 cgagcgccat gcccacctgg ctgctcgccg gcccgggcag gaactggcac agcgccacca
     1681 ggtcggcata ggcgcgctcg tccagccagc gcctgcgcgc gacgaactcg gcgtggaaat
     1741 agcccaggtg cgccaccggc ccgccgaagg aggtgaggcc caggcgcagg aagatcagga
     1801 acacggccca cgggctgtgc tcggtgtgct tcgcttcgtt catgtcgcgt ttcgcaaaag
     1861 aggatcgggt cgtgctggtt gatcggaatc gacttctccg ggcacgggcg catggcctgc
     1921 cccgtccgcg catcgacgag gcaggacgca ggatcgacag cggcgggggc cgcctccggc
     1981 gatcccgctc acctcagccg caggatccgc accgcccccg ccagcaccac caccgcgatc
     2041 agcaggccga tgatccagtc cggccacggc gtccccagcc aggccaccag cgcgccggcg
     2101 ccgatcacgc cgaggttggc gatgacgtcg ttggccgaga agatgtagct cgccttcatg
     2161 tgcacgccgc cctcgcggtg gcgggcgatc agcaccaggc aggcgacgtt ggccgcgagc
     2221 gcgagcagcg cgatgcccat catgcccacc ggctcgggca tcgcgccggc gagcatgcgg
     2281 cgcaccacct cggcgagcgc accgagcgcc agcaccagct gcagcacgcc ggccagccgc
     2341 gccgcggcga gcttgtggcg cgccgcccgc cccaccgcat agagcgccac gccatacacc
     2401 gcggcgtcgg cgaacatgtc catggcgtcg gcgatcaggc cggccgagcg cgcccacagg
     2461 ccggcgccaa gctccaccac gaacatcgac gcattgatcg cgagcagggt ccacagcacg
     2521 cgcgcctccg ccgcatcgtc gccgggcgcg gcggactgca tctcgccggc ggccagcgcc
     2581 cgcgactcgg ccagctcggc gccgtagccc agcggcacaa ggcgggcgag gatcgcctgc
     2641 gggtcgccgt cgtgatccac cgtcagccgc cgcccggcga ggtcgaacgc cagcgccgcc
     2701 accgccgcat cggccaggcg caggcggatc atctgctcct cggacgggca gtccatgccg
     2761 gggatgcgga acacgctgcg cgtgcgcgcc gcagcggaac ccaggcgcac ggcaggcccg
     2821 gcgcccgtcg ccagccgctg cagcctcggc ctgggcaccg cgccgccgca ctggccacaa
     2881 cagccgcctg cagcgtggtc gtcgccattc atcgagggct tgtcgctcaa atcgccactc
     2941 ctaacgcacg accggcttgc ggaacagcgg cacgagcagc atgtccgcct tcatcacgtg
     3001 atccaccagc cacttgcgca ggaaggcggt gatctcgccg ctctgcgcct tgatgccctc
     3061 caccccgccg tcgggatcct cgagggtggc atggatgcgc tgcgcgagga tgtcgatctc
     3121 ggccagcagc gcgcggtgct cgcgcttgtg ctggtcgaga tggaggtagc cgtaggcgat
     3181 ctggatgcgc tcctcgcgct cgaagtggta ttcggcgtag cgccgcagct cgatcagcgc
     3241 caggtcgacg ttgcgcgggt cgtccgggaa gcgcagcacg agctcgaccg tgttgatgag
     3301 caggatcagg tagcggtggt cggcgtcgat gtcgtcttgg ccgatacgga attgcggtcg
     3361 ccagaagatg ggcatgggag tctcgggagc cgttcagggt cgtggaaagg cggcgcgcag
     3421 gattgtcgcc gatgccgccg ccgcgggcat cacgcgacgg cgtcgcaccc tgccccgcga
     3481 cggaagacca ggctgaggtt gttggccggc atgcccacca cctcctccag cacgaagccg
     3541 cagcgctgcg cctcggcttc caccgtctcc aggtcgcgca ccgcgaagcg cgcatcgatg
     3601 ctgcgcagcc actcgtcgaa ctcggcgttg ctcggcgcgg tgtgcgcgct gccccggcgg
     3661 taggggccgt agcagaccac cacgccgccc gcgggcagga cctcggccgc gccggcaaac
     3721 agcgcgggcg tggtcggcca gggcgagtaa tgcagcacgt tgatcgccac gacggcatcc
     3781 gccgcggcga ccggccaggg cgtggcggcg aggtcgaagc acagcggcgg caacacgttg
     3841 ggcagcgcgg cgtgcaccac ccagtcggtg atcgaggcca gcgccgcggg gtcggcctcg
     3901 ctcggctgcc agcgcagcgc ggagaggtgg cgggcaaaat gcaccgcgtg ctcgccggtg
     3961 ccgctgccga gctcaagcac cagccctgcg ctcggcagca cgcgctgcag cacggcgagg
     4021 atggggtcgc ggttacgcgc ggcggagggc gagaactggc ggcggtcgaa aggagacatg
     4081 gagttcgacg ggcttgttga atgaggtttc gattatcgcc cgctccggct cggcgacgcg
     4141 atgcaaggat cttcctgccg acacggggat aatgacccca ttcctatcac cgccccaccc
     4201 cgccatgacc acacccacca aacccctcgc cggcatcaag gtcgtcgagc tcggcacgct
     4261 catcgccggc cccttcgccg cgcgcatcct cgccgagttc ggcgccgagg tgatcaagat
     4321 cgaatccccc gacggcggcg acccgttgcg caagtggcgc aagctctacg agggcacctc
     4381 gctgtggtgg tacctgcagg cgcgcaacaa gaagtcggtg acggtgaacc tgaagcaccc
     4441 ggacggcgtc gaggtggtgc gccggctggt ggccgaggcc gacatcgtgg tggagaactt
     4501 ccgccccggc gtgctcgaca agctcggcct gggctgggag gcgctgtcga agatcaactc
     4561 cggcctggtc atggtgcgcc tgtcgggctt cggccagagc gggccgatgg cgcagcagcc
     4621 gggcttcggc gccatcggcg agtcgatggg cgggctgcgc tacgtgaccg gctttcccga
     4681 ccgcccgccg gtgaagaccg ggatctcgat cggcgactcg atcgccgcgc tgtggggagc
     4741 gctcggcgcg ctgatggcgc tgcgccacaa ggaggtcaat ggcggcgcgg gccaggtggt
     4801 ggatgtcgcg ctctacgagg cggtgttcgc gatgatggag tcgctggtgc cggagttcga
     4861 cgtgttcggc ttcgtgcgcg agcgcaccgg caacatcatg ccgggcatca cgccgtcgaa
     4921 cacccacacc acccgcgacg gccgccacat caccatcggt gccaacggcg acgcgatctt
     4981 ccgccgcctg atgcgcgcga tgggccgcga ggacctcgcc gaggacccga cgctcgccga
     5041 caacgccggc cgcgacgcgc gccgcgacga gttgtacgcg ctcatcgacg cctgggtggc
     5101 gcagcacgac gaggccgcgg tgctggcgac gctggccgcc gccgaggtgc cggcctcgcg
     5161 catctactcg gtggccgaca tgttcgccga tccgcaattc ctcgcccgcg agatgctgca
     5221 cacggtgacg ctgcccgacg gccgcgactg ccgcatgccg ggcgtggtgc ccaggctgtc
     5281 ggccacgccg ggcggcagcg agtggatcgg gccggcgctg ggcgaacaca ccgacgcggt
     5341 gctggcgggg ctgggttacg acgaggcccg catcgccgcg ctgcgcgcgg ccggcgcgat
     5401 ctgatccggc gatctccagg cccggatctc catgcgggag gcccatgcag gagcgccggc
     5461 aggcgcgaat acagcgctga aacaagcgcc gcccccatcg gcgccgcccg cctcgcctca
     5521 cccgccccac gcagtcaagc ctggcgcggc acccggccga ccagccccca ggccaccgcc
     5581 gcggtcgcca cgctccagaa ccacacgccg tggatcatcg gcagcgacgt accgtccatg
     5641 ctcgcgccca gccactgccc catcgcgaag gccaccacca tcatcacgaa gccgctcatc
     5701 gccgaggcgg cgcccgccgc cttcgggaag ggcccgaccg cgcccgcctg gccgcagggc
     5761 tggtggatgc catgcccgag catgtagatc agcatcggca gcaggatcgg ccacaccccc
     5821 tccaggccgg ccatcccgcc gagcccgagc aggctgccac ccagcagcga gaacacgccg
     5881 ccgatcgcca ccgtgcgctg caccccgaag cgcaccagca ggcgccggca cagcagggtc
     5941 ccgcccacat aggccaggac gatcacgaac atcagcgcgg catactcgat gcgcgacagc
     6001 tccatcaggc ggatgaacac gaaggacgag gccgccagca gggtgaacag gccgccgtag
     6061 gtcgccgcgg ccagcagcgc gaaggcgagg aaggtggggt tgcgcaggat ggcgagccag
     6121 gtgcgcacca gcgtgcccgg gcgcagcgca tccggatcgg ggcgctgcag cgtctcctcg
     6181 aagcgcagcg cgatcagcgc cagcgtggcg gcaccgaaca gcgccggcgc cgacagcgcg
     6241 atgcgccagc cgaagaactc cgcgagcacg ccgccgagcg ggatgctcag gcaggcgatc
     6301 acgcccagcc cggtgagccc cttgctgatc gcgcgcgcac cgagctcggg actgtagagg
     6361 tcgcgcacca gcgcacgcgc gcacatcacc gaggccccca gcgccgcacc ctggacgatc
     6421 cgccacagca gcagcgcctc catcgaccca gcgagcgcgc cgcccaccgc ccccacgaca
     6481 taggtcgcca gcccgagcag gagcaccggc cggcggccga agcggtccga gatcggcccc
     6541 cacaccagct gcgacaggcc gaaggcgagc agcagtccgg acagcgtgag ctgcgcctgg
     6601 gccaccgtgg cgccgaggtc ctgggtgagc gcgggcagcg ccggcaggta gagatcggtg
     6661 gtaaccggct ggaggccgag cagcagcgac aggacgagga cgatgaaggc ggtcgacatc
     6721 gggactccga caagggggaa agcaagccca cgcaacatag cgccggcggc gggcgaaagg
     6781 gtgaacagtt cgccccccgg caacctcgcg cgcatcaagc ccgagcccct gcgcccaccg
     6841 tttccgagcc ctcgccggcg gcgtcggagc gaccgtgcag gctgctcact cggcgtcggg
     6901 ctgggcctcg ggcgcggcgc ggcggaaggc ctccaggccg gcgcagcggt ccgcgatgcg
     6961 cagcaccgtc ggcatcgccg acagctcgca gccgaagcgg cgggcgttga agacctgcgg
     7021 caccaggcag cagtcggcca ggccgggggt gtcgccgtgg cagaacgcgc cggtgcgcgc
     7081 atcgccggcg agcatcgcct cgaccgcctg caggccgacg ccgatccagt gccggtacca
     7141 ggcgttcttc tgcgcctcgc tcgcgccgag ctcgcgcgtg aggtactgca gcacgcgcag
     7201 gttgttcacc gggtggatgt cgcaggcgat cgcctgcgcg atcgcgcgca cgcgggcgcg
     7261 gtcgagcgcc gcggcgggca gcaacgcggg ctgcgggtgg gtctcctcga gatactcgac
     7321 gatcgccagc gactgcgtca gcacctggcc cgcatcctcc agcgccggca ccagcccggc
     7381 ggggttgagc ccgaggtagg ccggctggcg gtgctcgccg ccgccgcgca ccaggtgcac
     7441 cggcacggcc tcgtagtcca ggcccttgag gtgcaacgcg atgcgcacgc gataggcggc
     7501 ggagctgcgg aaataggtgt ggagcttcat cccctcagcc cttgcgcgcc gccacccggt
     7561 tctcgatggt gccgaagacg ctggcgccct ggcggtcgaa catctcgatg cgcacgacgt
     7621 cgccgtcgcg catgaagggc gtggccggct tgccctgctc gatggtctcg taggtgcgca
     7681 cctcggcgag gcagcagtag ccgacgccgc cgtggtcgat ggacgacccc cacaggtcgc
     7741 cctgcttgtt cgacaccgtg cccgagccga tgatcgagcc ggcctcgagc tcgcgcgtct
     7801 tcgccacgtg ggcgacgagt tggccgaagt cgaaggtcat gtcgacgccg gcctcgggct
     7861 tgccgaagag cttgtcgttg aggtgcacca ccagcggcag atgcaccttg gcgtcctgcc
     7921 aggcgtcgcc gagttcgtcg ggcgtgaccg ccaccgggct gaaggccgag gccggcttgg
     7981 actggaagaa gccgaagccc ttggcgagct cgttggggat gaggttgcgc aggctgacgt
     8041 cgttcaccag catcaccagg cggatcgcct tcgccgcctc ggcgggggtg gcgcccatcg
     8101 gcacgtcgcc ggtcaccacg gtgacctcgg cctcgaagtc gatgccccag gcctcgtcgg
     8161 ccaccaccgc gtcgcgcggg ccgatgaagc tgtccgagcc gccctggtac atcagcgggt
     8221 cggtgtagaa cgagggcggc atctcggcgt tgcgggcctt gcgcaccagc tcgacgtggt
     8281 tgatgtaggc cgagccgtcg gcccactggt aggcgcgcgg cagcggcgag gcgcaggcgg
     8341 cctggtcgaa gggctgggcg tcgaccgcgc cgctgttgag cgcctcgtac acctggcgca
     8401 gctgcggctc gcaggcctgc cagtcgtcga gcgcggcctg caggctgcgg gcgatcgccg
     8461 gcacggcgcg gcagcgggcg aggtcgcggc tgacgacgac cagggtgccg tcgcggccgc
     8521 cttgcttgag ggtggcgagt ttcactggaa catctccttg tagctgccgt catgcatcca
     8581 ggcggcgtgc ttgggggcct tcttcgtctg cgcccactcc tcgagcatgt cccacttgac
     8641 cttgtcgagc gcctccagca tgccgggtcg gttcgtgttg caggcgagct cgaggcggtg
     8701 gccgttggga tcgaagaagt agatcgactg gaagagggcg tggtcggtgg ggccgacgac
     8761 ctggatgccc gcggattcga ggcgggcctt ggcggcgagc agggtctcca tcgagtcgac
     8821 ctccagcgcc aggtgctggg tccaggccgg ggtgttctcg tcgcggccca tcggcgcgcg
     8881 cgtgggcagc tcgaagaagg cgagcacgtt gcccatgccg gcgtccatga agatgtgcat
     8941 gtaggggtcg ggctcgccgg tcgagggcac ggcgtcctcg gcgatcgaca gcacgagctt
     9001 catgccgagg tgcttctcgt accagcgcgc ggtctcgagc gcgtccttgc agcggtaggc
     9061 gacgtgatgg atcttcttca cgatcggggt cattgcggtc tcctcgtcct tgttcagtgc
     9121 cgtcgcgccg tggtggcatt tcggccagtt caccgagcga tacggtccgg gcatcatcat
     9181 tgcagcgatc tcgctcgctg cacatcctct gcggcacggc cgccacgggc cggttcgcgc
     9241 ggtgctcaat ccttgctcgc cactcctgcg cgcgcgatgc tcatcgcctc gcgcagcacc
     9301 gagatgtcgc cgatatggtt ggcgagcagc aggatcaggc gggcattcac catctcgctc
     9361 tgctcgtcgc tgagctcgcg gtgggtctcg atgagggcct cgtagaaatc gtcgccgggc
     9421 gagaaggcgc ggaagtagcg cttgccgggt tcgaacaggt tgggttgggt gttcagggcc
     9481 atggcgatct ccttcaggcg ttgcaggtgg cgcgggcgac tgcggcgcgc acgcgggccg
     9541 ggtcgagggc gcgccagcgc gcggtgacgt gctggtcggg gcggacgagg taggtggtgc
     9601 cgggctgcag gtcgtagcgc tcgcggatgc gacccttggc gtcggtcagg gtgcgcaggc
     9661 cggccggggc ctggccgcgc gcggcgacca caatcggctc gaccggaatc gcgccctcgg
     9721 cgagcgactg cagcgccgcc acgctcgcgg cgtcgaggtc ggccgcgtcg gcgacgtagt
     9781 gcagcacctg gaagcggtcg ccgagcacct gcagcagcca ggactcgccg tcggcggtgg
     9841 cgatcggggc gtcgtccatc ggcgcgccgg ggaccatgtt gccggcgaac accgcgtcgt
     9901 cggcggtgtt gagccgcgag cccacgagga agctcggcac cgacaggcgc ccggagttga
     9961 ccagcgcgcg cgcgaaggcg tggtgctcgg cgaggcccag caccgcgttg cggaaggtct
    10021 tgctggtgcg actcttgggg gtgatgaagt cggtcgagcg cgtcgagttc atgatgttct
    10081 cgtcggccgc gaagccgcgc tcgtcgccgt aggtgtcgag cagcgtggcg ggggccttgc
    10141 cgtccatcac cagcgcgagc ttccacacca ggttgtcggc gtcctggatg ccggagttgg
    10201 cgccgcgcgc gccgaagggc gagacctggt gcgccgagtc gccg
//
LOCUS       DAOTIN010000116        10175 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_7838_length_10175_cov_8.821443, whole genome shotgun sequence.
ACCESSION   DAOTIN010000116 DAOTIN010000000
VERSION     DAOTIN010000116.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 10175)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 10175)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10175
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_7838_length_10175_cov_8.821443"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1873)
                     /locus_tag="P5537_13785"
     CDS             complement(<1..1873)
                     /locus_tag="P5537_13785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hybrid sensor histidine kinase/response
                     regulator"
                     /protein_id="HRV79157.1"
                     /translation="MTHATEPDLGPLTWVKGEIDAALGRAREILERGCAGSGAAGLQF
                     AQSHLHQVRGALDIVGLDGLTLFTDAVEQLLGAMARGEVPADAARHALALRALAMIGN
                     YLEELADGAPDQPLRLATRYLELAAARGRHDASAADLFHPDLSRRPPARAAVPAGAAD
                     TEAQALRAARSRFERGLLEWLRKGAAGEGARTMRDAIAEVEAQQRSPAARSLWWASLA
                     FYDALIHGGLQPDPAVKRLCTQLDAQFRRLLGGTPSVPDRLLRELLYQIARAPAQTEQ
                     QRAVRACWQLDAQIPEPGTEVGETPISPLLDALRTRLGQAREHWEAFCAGTAVALPRF
                     EDDLAAMTTPAEALGRPGVRTLCAALLDFARWLRRDPLQFAEAAGMEVATALLGLEGA
                     LERRPPPTGFGTRAEGIASRLLALQRGEVLPDGTIVAEPADARQAQERAALEQVAKEM
                     LASLAHVEQVLDDFFRNPARRDPLLQLHQPLQQIIGALSMLGETDALALVRDAAIHIA
                     SLAREDSQAGQAEFERLARDLSALGFYIEALPHGGASLDELLDPGLRRRRAPAAEEAS
                     EPALSASTPPATPAVPLSAWEVEPAPAAPPLVPEPAVPEAAVPEPAVPEPAVPEPAVP
                     "
     gene            complement(1903..4017)
                     /locus_tag="P5537_13790"
     CDS             complement(1903..4017)
                     /locus_tag="P5537_13790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HRV79158.1"
                     /translation="MALNPFGKKTPASATGTEAQTIIETSAPEQATASKLPPAPARPG
                     GRLGMLGGIFVACAAISAGLLVYQAREASLSALQLGAASELQALPGQMAKSGRLARLG
                     ESAALTELDQARTRFASLMQVLGEGGSHAGAMLPPLPASMQPLLQELDTQWQKSATLA
                     AGLGGQGATLAGTRAAVQGINAASAAFVDAADQLGRRMLAVNGDASALRATHALLLHA
                     QRAALHANALFATDADLSSTAGALAGEAEQLRQRLAELERMGSGGALDDSLRTLRAAA
                     TPILDATENIGANAGALQQANQASAGLTANTPALLAASSALGAALAGRTGGFGPLHAG
                     AAVAALLALLALFMMARAYAADAAARRSASEAERRQAEDERNLTQQAILRLMNEMGDL
                     ADGDLTVRATVTEDITGAIADSVNYTIEELSVLVRRINDAATRVTSATESARRTSTEL
                     LAATDRQSQEIEEAGANAERMAQSMTDSSARALQSAQVARRSLESARKGADAVQNSIR
                     GMNDIRSQIQETAKRIKRLGESSQEIGEIVELISDITEQTNVLALNAAIQAATAGEAG
                     RGFTVVAEEVQRLAERSAEATKQIAAIVKTIQTDTQDAVGAMENATRDVVEGTQLSDA
                     AGQALAEIGLVSTETASLIERISADVQEQAATAGRVAAAMKDILAVTEQTSLGTRQTA
                     VSIDQLAELAVELKGSVSGFKV"
     gene            complement(4064..4570)
                     /locus_tag="P5537_13795"
     CDS             complement(4064..4570)
                     /locus_tag="P5537_13795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004383339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HRV79159.1"
                     /translation="MARSSLREFQERLARRLAEAAGSERRGLLGFQCGENNWLIELAD
                     AGEILPPPPLSPVPLTRPWFRGLANVRGSLYGVVDFAAFNGQPPISPAGRARLLLIGA
                     RHGVHSALLVSSSSGLRSHEDFEPAPADGAPPWVARRLRDMQGREWLQLDPARLLAQP
                     AFLDAGLE"
     gene            complement(4577..4942)
                     /locus_tag="P5537_13800"
     CDS             complement(4577..4942)
                     /locus_tag="P5537_13800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV79160.1"
                     /translation="MPIRKILVADDSPVERLALQEVLTRNGYQVLTAENGEQAIARSR
                     SDHPDLILMDVVMPGMNGYQATRTISRHDETRDIPIIMCTSKGQETDKIWGMRQGALD
                     YLVKPVDHDELLARIRAMG"
     gene            complement(4962..5363)
                     /locus_tag="P5537_13805"
     CDS             complement(4962..5363)
                     /locus_tag="P5537_13805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004383335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV79161.1"
                     /translation="MDLAGLKVMVIDDSNTIRRSAEIFLAQAGCEVVLAEDGFDALAK
                     IADHHPDVIFVDIMMPRLDGYQTCALIKKNPRLSPTPVIMLSSRDGLFDRARGRMAGS
                     DEYLTKPFTKDSLLRAVASHARRGDGAAHTG"
     gene            complement(5404..5556)
                     /locus_tag="P5537_13810"
     CDS             complement(5404..5556)
                     /locus_tag="P5537_13810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017406135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubredoxin"
                     /protein_id="HRV79162.1"
                     /translation="MCLICGFIYDEASGLPDEGIAPGTRWEDVPPNWTCPECNARKED
                     FEMVEI"
     gene            5675..6562
                     /locus_tag="P5537_13815"
     CDS             5675..6562
                     /locus_tag="P5537_13815"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HRV79163.1"
                     /translation="MPLAIPETPPCVLCLSAGDATAGSGLAADILTLASMGCHPLPVQ
                     TAALVRDTRGIDELWPAAPELIAMQARAVLEDVPVAAFKLGFCGSVENVAVIAEILAD
                     YPDVPLVVEPGLHAAALLGEAGEEIAAALADLILPQTTLLVADRHELLRLTGLAGDEA
                     GELDDDEDAGEAGDGGAGSAEVDEALERLLGNGTEYVLLTGGGDHGPQLVDTLFGSEG
                     IVRTDAGPRPAAPCLGAGTTLAAAAVAAMAHGMELPEAVREAQEFTRQALRHAYRAGM
                     GRALPDRFFWARGKDAGDD"
     gene            6555..7196
                     /gene="thiE"
                     /locus_tag="P5537_13820"
     CDS             6555..7196
                     /gene="thiE"
                     /locus_tag="P5537_13820"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HRV79164.1"
                     /translation="MTERFPARALRGLYAVTPEEPDTGRLLARAQAVLAGRPALLQYR
                     NKGADAGLRREQAQALRDACRVAGVPFIVNDDLALALEIDADGAHLGREDGPPAEARA
                     ALGAQRILGLTCYADWPRATEGAAVGADYIAFGAMFPSMTKPHAPPAPFALIGRAQRE
                     LGLPVAAIGGITLERAPQVIAAGADLLAVVGDVFGATDPAARALAYGALFRAP"
     gene            7270..8553
                     /gene="hemL"
                     /locus_tag="P5537_13825"
     CDS             7270..8553
                     /gene="hemL"
                     /locus_tag="P5537_13825"
                     /EC_number="5.4.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0042286 - glutamate-1-semialdehyde
                     2,1-aminomutase activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="HRV79165.1"
                     /translation="MTSRNEALFQRAQRSIPGGVNSPVRAFRSVGGTPRFLARAEGAR
                     VWDADGKEYIDYVGSWGPAIAGHAHPAIVEAVREAALKGLSFGAPTESEVDMAELICA
                     MLPSVEMVRLVSSGTEATMSAIRLARGFTGRDAIVKFEGCYHGHADSLLVKAGSGLLT
                     FGNPSSGGVPADFAKHTIVLDYNDLQQVEDVFKARGDEIAAIIVEPVAGNMNLIKPQP
                     GFLEGLRRICTEYGAVLIFDEVMTGFRVGPQGVQGLYGITPDLTTLGKVIGGGMPVGA
                     FGGRRDIMEKIAPLGSVYQAGTLSGSPVAVAAGMVSLKLTREAGFYDKLTASTQRLVA
                     GLAAAARDAGVTFSADSVGGMFGVYFADKVPASFAQVMATDKDRFNRFFHAMLEAGHY
                     FAPSAFEAGFVSVAHGEAEIDATLAVAREVFAQLG"
     gene            complement(8617..10059)
                     /gene="mgtE"
                     /locus_tag="P5537_13830"
     CDS             complement(8617..10059)
                     /gene="mgtE"
                     /locus_tag="P5537_13830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004371933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HRV79166.1"
                     /translation="MTEPEELHPDDVQHHLKEVQDLLARQKVVEGLVHRQDMPRHELV
                     ENLVHKQHEAGLRAKLDTLHPADIAYILEALPREERLYVWDLVKAERDGEILLEVSDA
                     VRESLIETMAPEELKAAAGSLDADELADLAPDLPPEVIEDVFQSLDTEGREQLRAAMS
                     YPEDSVGALMDFDMVTVRDDVTLEVVLRYLRRFDELPDHTDKLFVVDREDHLEGILTL
                     ETLLISDPEKTVAEVMRSEPVISFTPEDEADDAAQAFERYDLVSAPVIDSERRVIGRI
                     TVADAVDFIREESEAEILSQAGLREEEDIFASVWSSVKNRWAWLAINLVTAFVASRVI
                     GLFEESIEKLVALAALMPIVAGIGGNSGNQTVTMIVRAIAMGQVEPSAMTRLLRKELG
                     VALINGLVWGSLLGVLSWWLYGNVDLGLVMTAAMTLNLLLAACAGVVIPMLRQRLGAD
                     PALGGSVMITALTDSGGFFIFLGLATLFLL"
BASE COUNT         1315 a         3488 c         3812 g         1560 t
ORIGIN      
        1 cgggcaccgc gggttcgggt accgcgggtt cgggtaccgc gggttcgggc accgcggctt
       61 cgggtaccgc gggttcgggc accaggggcg gtgcggcggg cgcgggttcg acttcccagg
      121 cgctgagcgg tacggctggc gtggcgggag gggtggaggc cgacagtgcc ggctccgacg
      181 cctcttcggc ggctggtgcg cgcctgcgcc gcaggcccgg atcgagcaac tcgtccaggc
      241 tggcgccgcc atgcggcagc gcctcgatgt agaaaccgag cgcggagagg tcgcgagcga
      301 ggcgttcgaa ctcggcctgg cccgcttggc tgtcctcgcg cgcgaggctg gcgatgtgga
      361 tcgcggcgtc gcgtaccagg gcgagcgcgt cggtctcgcc gagcatgctc agcgcgccga
      421 tgatctgctg cagcggctgg tggagctgca gcagtgggtc gcgccgtgcc gggttgcgga
      481 agaagtcgtc cagcacctgc tcgacatggg cgaggctggc gagcatctcc ttcgccactt
      541 gctcgagcgc ggcgcgctcc tgcgcctggc gggcatccgc cggttccgca acgatcgtgc
      601 cgtcgggcag gacctcgccg cgctgcaggg cgagcagccg ggaggcgatg ccttccgcgc
      661 gcgtgccgaa tccggtcggc ggcgggcgac gctcgagtgc gccctccagg cccagcaggg
      721 cggtggcgac ctccatgccc gcagcctcgg cgaactgcag cgggtcgcgg cgcagccagc
      781 gcgcgaagtc gagcagcgcg gcgcacagcg tgcgcacgcc gggtcggccg agcgcctcgg
      841 cgggcgtcgt catcgctgcg aggtcgtcct cgaagcgggg cagggccacc gcggtaccgg
      901 cgcagaaggc ttcccagtgc tcgcgtgcct ggccgaggcg ggtgcggagc gcgtcgagca
      961 gggggctgat cggcgtctct ccgacctccg ttcccggctc cgggatctgc gcgtcgagct
     1021 gccagcatgc gcgcaccgcg cgctgctgtt cggtttgtgc gggtgcgcgc gcgatctggt
     1081 acaggagctc gcgcagcaga cggtcgggga ccgagggtgt gccccccagc aggcggcgga
     1141 actgtgcgtc gagctgggtg cacaggcgct tgaccgccgg atcgggttgc aacccgccgt
     1201 ggatcagggc gtcgtagaag gcgaggctgg cccaccacag gctgcgcgcg gccgggctgc
     1261 gctgctgcgc ctcgacttcg gcgatcgcgt cgcgcatcgt ccgggcacct tcgcccgcag
     1321 cgcccttgcg cagccactcc agcaggccgc gctcgaagcg gctgcgcgca gcgcgcagcg
     1381 cctgcgcctc ggtgtcggca gcgcccgcgg gcacggctgc gcgtgccggc ggccggcgcg
     1441 acaggtccgg atggaagagg tcggcggcgc tggcgtcgtg ccggccgcgt gcggcggcga
     1501 gctcgaggta gcgcgtggcg agtcgcagcg gctggtcggg cgcaccatcg gcgagttcct
     1561 cgaggtagtt gccgatcatc gccagcgcgc gcagggcgag cgcgtggcga gcggcgtcgg
     1621 ccgggacctc gccgcgcgcc atggcgccga gcagctgttc gacggcgtcg gtgaacaggg
     1681 tcaggccgtc gaggccgacg atgtcgaggg cgccgcgcac ctggtgcagg tgcgactgcg
     1741 cgaactgcag gccggcggct ccgctgcccg cgcagccgcg ctcgaggatt tcacgcgcgc
     1801 gtcccagcgc ggcgtcgatc tcgcccttga cccaggtcag cggtcccagg tccggctcgg
     1861 tggcgtgtgt catgctgttc ttccgggcga cagccagcgt tgtcagacct tgaagcccga
     1921 gaccgagccc ttcagctcca ccgccagctc ggcgagctgg tcgatcgaca cggcggtctg
     1981 gcgggtgccg agcgaggtct gttcggtgac cgcgaggatg tccttcatcg ccgcggcgac
     2041 gcggccggcg gtcgcggcct gctcctgcac gtcggccgag atgcgctcga tgaggctggc
     2101 agtctcggtg gacaccaggc cgatctcggc cagcgcctgg ccggcggcgt cggagagctg
     2161 ggtgccctcg accacgtcgc gggtggcgtt ctccatcgcc cccacggcgt cctgggtgtc
     2221 ggtctggatg gtcttgacga tcgcggcgat ctgcttggtc gcctcggccg agcgttcggc
     2281 gaggcgctgc acttcttccg cgacgacggt gaagccgcgc ccggcctcgc cggcggtggc
     2341 ggcctggatc gcggcgttga gcgcgagcac gttggtctgc tcggtgatgt ccgagatgag
     2401 ctcgacgatc tcgccgatct cctgcgagga ctcgccgagg cgcttgatgc gcttggcggt
     2461 ctcctggatc tggctgcgga tgtcgttcat gccgcggatg ctgttctgca ccgcgtccgc
     2521 acccttgcgc gcggactcga gcgagcgccg cgccacctgg gcggactgca gggcgcgcgc
     2581 ggacgagtcg gtcatcgact gcgccatgcg ctcggcgttg gcgccggcct cctcgatctc
     2641 ctgcgactgg cggtcggtgg cggcaagcag ctcggtggag gtgcggcggg ccgactcggt
     2701 cgcggaggtg acccgcgtgg cggcgtcgtt gatgcggcgc accagcaccg agagctcctc
     2761 gatggtgtag ttcaccgagt cggcgatcgc cccggtgatg tcctcggtga ccgtggcgcg
     2821 cacggtgagg tcgccgtcgg cgaggtcgcc catctcgttc atgaggcgca ggatggcctg
     2881 ctgggtgagg ttgcgctcgt cctcggcctg gcggcgctcg gcctccgagg cgctgcggcg
     2941 cgccgcagcg tcggcggcgt aggcgcgcgc catcatgaac agggcgagga gggcgagcag
     3001 ggcggcgact gccgcgcccg cgtgcagcgg accgaagcct ccggtgcgcc cggcgagtgc
     3061 cgcgccgagg gcggagctcg cggcgagcag ggcgggggtg ttcgcggtga ggcctgcgct
     3121 cgcttggttg gcctgctgca gggcaccggc attggcgccg atgttctccg tcgcgtcgag
     3181 gatcggcgtt gcggcggcgc gaagtgtgcg caggctgtcg tcgagggcgc cgccgctgcc
     3241 catgcgctcg agctctgcca ggcgctggcg cagctgttcg gcctcgccgg cgagcgcgcc
     3301 agcggtggag gacaggtccg catcggtggc gaagagtgcg ttggcgtgca gtgcggcacg
     3361 ttgcgcatgg agcaggaggg cgtgggtggc gcgcagtgcc gaggcgtcgc cattcacggc
     3421 cagcatgcgg cggccgagct ggtcggccgc gtcgacgaag gcggcgctgg cggcgttgat
     3481 cccctgcacg gcggcgcggg tacctgcgag cgtcgcgccc tgtccgccga ggccggcagc
     3541 cagcgtggcg ctcttctgcc actgcgtgtc gagctcctgc agcagcggct gcatgctcgc
     3601 ggggagcggc gggagcatgg cgccggcgtg gctgccgcct tcgcccagga cctgcatcag
     3661 gctcgcgaag cgtgtcctgg cctggtccag ttcggtgagc gcggcgctct cgccgaggcg
     3721 ggcgaggcgg cccgacttgg ccatctgtcc cggcagggcc tgcagttcgc tcgccgcacc
     3781 gagctggagt gcggagaggc tcgcctcgcg cgcctgatac acgagcagcc cggcgctgat
     3841 cgccgcgcat gccacgaaga tgccgccgag catgccgagc cggccgccgg gccgggcggg
     3901 agcggggggg agcttgctgg cggtcgcctg ctccggtgcg gaggtctcga tgatcgtctg
     3961 tgcctcggtg ccggtcgcgg aggccggggt tttcttgccg aacgggttca atgccatgat
     4021 cgatgctcga ttgcggtcgg ggtctttcgg gggcgggcgc gagctattcc agcccggcgt
     4081 cgaggaaggc gggctgtgcg agcaggcgag cagggtcgag ctgcagccac tcgcggccct
     4141 gcatgtcgcg cagccggcgt gccacccagg gcggggcgcc gtcggccggg gcaggctcga
     4201 agtcttcgtg gctgcgcagc ccgctcgagg aggacaccag cagcgcgctg tggacgccat
     4261 ggcgcgcgcc gatcagcagc aggcgcgccc gcccggcggg gctgatcggc ggctgaccgt
     4321 tgaaggcggc gaagtcgacc acgccgtaga ggctgccgcg cacgttggcg aggccgcgga
     4381 accaggggcg ggtgagcggc accggcgaca acggaggtgg aggcaggatc tcgccagcat
     4441 cggcgagttc gatcagccag ttgttctcgc cgcactggaa gccgagcagg ccgcggcgct
     4501 cgctgccggc ggcctcggcc aggcggcggg cgaggcgttc ctggaattcg cgcaggctgc
     4561 tgcgggccat ggaggatcag cccatcgccc ggatgcgggc aagcagttcg tcgtggtcga
     4621 ccggcttgac caggtagtcg agggcgccct ggcgcatgcc ccagatcttg tcggtctcct
     4681 ggcccttgct ggtgcacatg atgatcggga tgtcgcgcgt ctcgtcgtgg cgcgagatcg
     4741 tgcgcgtggc ctggtagccg ttcatgcccg gcatcaccac gtccatcagg atcaggtcgg
     4801 gatggtcgct gcggctgcgc gcgatggcct gctcgccgtt ctcggcggtc agcacctggt
     4861 agccgttgcg ggtaagcact tcctgcaggg cgaggcgttc gacgggggag tcgtcggcca
     4921 cgaggatctt gcggatcggc atcggtcgtc tccggcttgg ttcagcccgt gtgcgcggcg
     4981 ccgtcgccgc gccgcgcgtg gctggcgacc gcccgcaaca ggctgtcctt ggtgaagggt
     5041 ttcgtgaggt attcgtcgga tcccgccatg cgtccgcgcg cgcggtcgaa gaggccgtcg
     5101 cgcgaggaca gcatgatcac cggggtcggg gacaggcgag ggttcttctt gatcagcgcg
     5161 caggtctggt agccatcgag gcgcggcatc atgatgtcca cgaagatgac gtcggggtgg
     5221 tggtcggcga tcttcgcgag cgcgtcgaaa ccgtcttcgg cgagcacgac ctcgcaaccc
     5281 gcctgggcga ggaagatctc ggcgctgcgc cggatcgtgt tgctgtcgtc gatgaccatc
     5341 accttcaggc cggcaaggtc catgctgtat tcctggtggg ttgtcgggcg gcagggtcgg
     5401 ggcctagatc tcgaccatct cgaagtcttc cttgcgcgcg ttgcactcgg ggcaggtcca
     5461 gttcggcggc acatcctccc agcgcgtgcc cggcgcaatg ccctcgtcgg gcaggccgga
     5521 ggcctcatcg tagatgaagc cgcagatcag gcacatgtag gtcttccagg gcgtatcggc
     5581 catgttccag cgtgacttta gggttggggg tagaatcggt cgcctatctt aacgcatccg
     5641 cccgcgcccc atccgcgctg catttccgcc tcccatgccg ctcgccattc ccgaaactcc
     5701 cccatgcgtg ctgtgcctgt cggcgggcga tgccacggcc ggcagcgggc ttgcggccga
     5761 catcctgact ttggcgagca tgggctgcca ccccttgccg gtgcagactg cggcgctggt
     5821 gcgcgacacc cgtggcatcg acgagctatg gccggccgcg cccgaactca tcgccatgca
     5881 ggcgcgcgcg gtgctcgagg acgtgccggt ggcggcgttc aagctcggct tctgcggcag
     5941 cgtcgagaac gtcgcggtga tcgcggagat cctcgccgat tatccggacg tgccgctggt
     6001 ggtggagccc ggcctgcacg ccgcggcgct gctcggcgag gcgggggagg agatcgctgc
     6061 cgcgctcgcc gacctgatcc tgccgcagac cacgctgctg gtggccgacc gccacgagct
     6121 gctgcgcctg accgggctgg ccggggacga ggcgggcgag ctcgacgacg atgaagatgc
     6181 gggcgaggcg ggcgatggcg gggcgggcag cgcggaggtc gacgaagcgc tggagcgcct
     6241 gctcggcaat ggcaccgagt acgtgctgct caccggcggc ggagaccacg gcccgcaact
     6301 ggtcgacacc ctcttcggca gcgagggcat cgtgcgcacc gacgccggcc cgcgccctgc
     6361 ggcgccctgc ctgggggctg gcaccacgct cgccgccgcc gcggtggcgg cgatggcgca
     6421 cggcatggaa ctgcccgagg cggtgcgcga ggcacaggag ttcacccgcc aggccttgcg
     6481 tcacgcctac cgcgcaggca tggggcgggc gctgcccgac cgcttcttct gggcgcgcgg
     6541 caaggacgcg ggcgatgact gagcgtttcc cggcgcgcgc gctgcgcggc ctctacgcgg
     6601 tcacccccga ggagcccgac accgggcgcc tgctcgcacg cgcgcaggcc gtgctcgcgg
     6661 gccgtccggc actgctgcag taccgcaaca agggcgccga cgccggcctg cgccgcgagc
     6721 aggcgcaggc gctgcgcgac gcctgccggg tcgccggcgt gcccttcatc gtcaatgacg
     6781 acctcgcgct ggcgctcgag atcgacgccg acggcgccca tctcgggcgt gaggatggcc
     6841 cgcccgcaga ggcgcgcgcg gcgctgggcg cgcagcgcat cctcggcctt acctgctatg
     6901 ccgactggcc ccgtgccacc gagggtgccg cggtcggcgc cgactacatc gccttcggcg
     6961 cgatgttccc ttccatgacc aagcctcacg cgccgcccgc gcccttcgcg ctgatcggac
     7021 gtgcgcagcg cgagctcggc ctgccggtgg cggcgatcgg cggcatcacg ctggagcgcg
     7081 cgccgcaggt gatcgccgcc ggcgccgacc tgctcgcggt ggtcggcgac gtcttcggcg
     7141 ctaccgatcc ggcggcgcgt gcgctggcct acggcgccct tttccgcgcg ccttgacctg
     7201 cacggtggac ccggcgcgtg tgcggcgcga caatgccgcc tttcgcacgc agcacaggaa
     7261 ccctctgcca tgaccagccg taacgaagcc ctcttccagc gcgcccagcg cagcatcccc
     7321 ggtggcgtca actcgcccgt ccgcgccttc cgctcggtgg gcggcacgcc gcgcttcctc
     7381 gcgcgcgccg agggtgcccg ggtgtgggac gcggacggca aggaatacat cgactacgtg
     7441 ggctcctggg gtccggccat cgccggccac gcccacccgg cgatcgtcga ggcggtgcgc
     7501 gaggcggcgc tgaagggcct gtccttcggc gcccccaccg agagcgaggt cgacatggcc
     7561 gagctgatct gcgcgatgct gccctcggtc gagatggtgc gcctggtgag ctccggcacc
     7621 gaggcgacga tgagcgcgat ccgcctcgcc cgcggcttca ccggccgcga cgcgatcgtg
     7681 aagttcgagg gctgctacca cggccacgcc gacagcctgc tggtgaaggc cggctccggc
     7741 ctgctgacct tcggcaaccc gtcctcgggc ggggtgccgg ccgacttcgc caagcacacc
     7801 atcgtgctcg actacaacga cctgcagcag gtcgaggacg tgttcaaggc acgcggcgac
     7861 gagatcgccg ccatcatcgt cgagccggtg gccggcaaca tgaacctgat caagccgcag
     7921 cccggcttcc tcgaaggcct gcgccgcatc tgcaccgagt acggcgccgt gctgatcttc
     7981 gacgaggtga tgaccggctt ccgcgtcggc ccgcagggcg tgcagggcct gtacggcatc
     8041 acccccgacc tgaccacgct cggcaaggtg atcgggggcg gcatgccggt gggcgccttc
     8101 ggcggccgcc gcgacatcat ggagaagatc gcgccgctcg gtagcgtgta ccaggccggc
     8161 acgctgtcgg gcagcccggt ggcggtggca gcggggatgg tgtcgctgaa gctgacgcgc
     8221 gaggcgggct tctacgacaa gctgacggcg agcacgcagc gcctggtcgc gggtctcgcg
     8281 gcggcggcgc gcgatgccgg cgtgaccttc agcgcggact cggtgggtgg catgttcggc
     8341 gtctatttcg ccgacaaggt gccggcgtcc ttcgcccagg tgatggcgac ggacaaggac
     8401 cgcttcaacc gcttcttcca cgccatgctg gaggccggcc actacttcgc gccttctgcc
     8461 ttcgaggccg gcttcgtgtc ggtggcgcat ggcgaggccg agatcgacgc cacgttggcc
     8521 gtggcgcgcg aggtcttcgc ccagctgggc tgaccctccc cgcaggcccg ccgcgcgggc
     8581 ctgccgcctc gctcctccct cctaacgccc aacgcttcac agcagaaaca gcgtcgccag
     8641 ccccaggaag atgaagaacc cgcccgagtc ggtgagcgcg gtgatcatca ccgagccgcc
     8701 gagcgcgggg tcggcgccga ggcgctggcg cagcatcggg atcaccacgc cggcgcaggc
     8761 cgccagcagc aggttcagcg tcatcgccgc ggtcatcacc aggccgagat cgacgttgcc
     8821 gtagagccac cacgacagca cgccgagcag gctgccccac accaggccgt tgatcagcgc
     8881 cacgccgagc tccttgcgca gcaggcgggt catcgccgag ggctcgacct ggcccatcgc
     8941 gatcgcgcgc acgatcatcg tcaccgtctg gttgcccgag ttgccgccga tgccggcgac
     9001 gatcggcatc agcgcagcga gtgccaccag cttctcgatc gactcctcga acaggccgat
     9061 gacgcgcgag gccacgaagg cggtgacgag gttgatcgcc agccaggccc agcggttctt
     9121 caccgagctc cacaccgagg cgaagatgtc ctcctcttcg cgcaggccgg cctgggacag
     9181 gatctcggcc tccgactcct cgcggatgaa gtcgaccgcg tcggccacgg tgatgcggcc
     9241 gatcacccgc cgctcggagt cgatcaccgg cgccgacacc aggtcgtagc gctcgaaggc
     9301 ctgggcggca tcgtcggcct cgtcctcggg ggtgaagctg atcaccggct cggagcgcat
     9361 cacctcggcc accgtcttct ccggatcgct gatcagcagc gtctccaggg tcaggatgcc
     9421 ctcgaggtgg tcctcgcggt cgaccacgaa gagcttgtcg gtgtggtcgg ggagctcgtc
     9481 gaagcggcgc aggtagcgca gcacgacctc cagggtgacg tcgtcgcgca ccgtcaccat
     9541 gtcgaagtcc atcagcgcgc cgaccgagtc ctcggggtag gacatcgccg cgcgcagctg
     9601 ctcgcggccc tcggtgtcga gcgactggaa gacgtcctcg atgacctcgg gcggcaggtc
     9661 gggggcgagg tcggcgagct cgtcggcgtc gagcgacccg gccgcagcct tgagctcctc
     9721 cggcgccatg gtctcgatga gcgactcgcg caccgcatcg gagacctcga gcaggatctc
     9781 gccgtcgcgc tccgccttga ccaggtccca gacgtagagg cgttcttcgc gcggcagcgc
     9841 ctcgaggatg taggcgatgt cggccgggtg cagggtgtcg agcttggcac gcaggccggc
     9901 ctcgtgctgc ttgtgcacga ggttttccac cagttcgtgg cgcggcatgt cctggcgatg
     9961 gacgagaccc tccaccacct tctggcgggc gagcagatcc tgcacttcct tgaggtggtg
    10021 ctggacgtcg tcggggtgga gttcttcggg ctcggtcatc gcgcgcaagg ccggcggagg
    10081 gggcaagccg cgaattctac ggactcccct ccgcgcatgc gaccccgatc atgtgacaga
    10141 gggcgaaaaa gcccccattc ccgcccctcg cacct
//
LOCUS       DAOTIN010000117        10149 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_7870_length_10149_cov_10.012582, whole genome shotgun
            sequence.
ACCESSION   DAOTIN010000117 DAOTIN010000000
VERSION     DAOTIN010000117.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 10149)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 10149)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10149
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_7870_length_10149_cov_10.012582"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..663
                     /locus_tag="P5537_13835"
     CDS             <1..663
                     /locus_tag="P5537_13835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HRV79167.1"
                     /translation="ADGSLVPPLDFIPFAEECGLISAIGARVLLRACHDAAAWMRRGL
                     RLRVAVNLSPMQFRAPDLLERVCEALDRSGLPPGLLELEITEGALMEDDARTRATLAA
                     LRGLGIGIALDDFGTGYSSLSYLKRLPLGRLKVDRSFVAGLPDDADNLAIVRAILALA
                     RHLGFRITAEGVETAAQAALLAGLEADSLQGYLFSRPVAAAQIEALAARSWTIGARDR
                     AD"
     gene            complement(719..1234)
                     /locus_tag="P5537_13840"
     CDS             complement(719..1234)
                     /locus_tag="P5537_13840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfiR family protein"
                     /protein_id="HRV79168.1"
                     /translation="MKPRVLLFLLALWSSPGVLAQALPELELKATYAYNFAALTLWPA
                     AARTTFNFCAYGDEGVAEAMRRLEGKTLHGRSVTVARLRSLSAIRDCDLLYVGANEAS
                     SLPQISALLGDAPVLTVTDAPPPQQAAVVIVAEGKRLAFEIDVERCHRAGLKPGASLL
                     GLARNLRRPAS"
     gene            complement(1231..3225)
                     /locus_tag="P5537_13845"
     CDS             complement(1231..3225)
                     /locus_tag="P5537_13845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002945249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HRV79169.1"
                     /translation="MSCRRFRGVVLGLGVLLAFQPGEGIAQDDLTALPFEELLRRDFV
                     SASRLARQVSDSPAAVAIVTADDIRAYGYRTLAEVINSMRGLYTTDERTYHYMGGRGF
                     GDVEDYAGRVMLLIDGYAVQDNLFDQAYIDESGLIDLELVERVEYVPGTGSVTYGNNA
                     LLGILNVVTRRGRDFDGARVSAEISSRGGSRQRATWGKRLDNGAEVLLSASTLDVDGR
                     NLYFPAYDTPATNHGVAEGLDGERSQRVFGKLAWGGWTVQAAWVEREKSVPTNPSAYT
                     AFNTPFPTRDESAFLGVRHETDLGLQLSSSSSLMLGRYGYWNQREYALNEDGEYDDGE
                     KYGVRDFTGAWWRFDQKFVGRWFTDHTLVFGAELRDDHRQSFRRRFLAPDGEVTYRDD
                     GERSRRTVSLYIADDYRLSDRWTLNLGARHDDADDLDGNLSPRVALIWQPDPATTWKA
                     SYSEAFKMPNANDRWTSDDTAVPEYVAATELVLQRQLAAHTRFTGALYRYRRSDLLVY
                     DDALEDYVPAGSSRAHGVEAEIEHLWERGARVRASVAWQRSRDVQGRDAVNSPDLLGK
                     LAYTFLLPGEALRAGVEAQYLGPRLTRERRMLGGHALAHLTLTTERDWHGLSASLSVR
                     NLFDRDYETVSGFDWRPGDVAQDGLRMDGRSVWLQIGYAL"
     gene            3319..5223
                     /locus_tag="P5537_13850"
     CDS             3319..5223
                     /locus_tag="P5537_13850"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009975 - cyclase activity [Evidence IEA];
                     GO_process: GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HRV79170.1"
                     /translation="MKTLEHIPLNGELPSPKGVALAILELCRKDDATIAEVARIAQTD
                     PALASRLIRQANSAAHGAGRPVASVTEAIMRLGMGTVRNLALGFSLVDQYQNGPCGQF
                     DYQGFWSHSLLMGLAMQRFSNMTGAGSSEELFACGLLAQVGRLSLATVYPMEYSRLLD
                     GQGAAAPNLVALEQEHLQTDHNELTAALLGEWGIPGALIEPIYHHEEPERSGFSPGSR
                     PFQLVHLFYLARRVADLGLAGESERNACTAELLLLGGKIGLDAEQLGATVDDLVLQWR
                     EWGELLRVPASALPSFAHMSAAHAMRDEGAGGAAALRVLLVDDDPTTRCMMEGVLAGA
                     LGHSVVCANNGREALALAVETQPQIVITDWMMPGMDGLDLARALRATEWGQTMYLIML
                     TGLETEDEVSAAFEAGVDDFLVKPVNVRTLRARLRAAWHYVQLLDAWERDRAQLKQFA
                     AELAISNRRLAHAAMTDLLTNLPNRRSGMNALAKAWAAASRFEQPLSVMMLDIDHFKR
                     INDGHGHAAGDTVLRDVAQAIQQSARKDDSVCRMGGEEFLVICPNTDLKAAIQAAERL
                     RRMVERLCIRAGDTEIRTSVSIGVATREVGMTETDALVNAADRALYRAKQAGRNRSCV
                     VVQGQMRCFP"
     gene            complement(5359..6876)
                     /locus_tag="P5537_13855"
     CDS             complement(5359..6876)
                     /locus_tag="P5537_13855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF853 domain-containing protein"
                     /protein_id="HRV79171.1"
                     /translation="MADPMLIARAHDKDQFKDICLLPRLANRHGLITGATGTGKTVTL
                     QKLAESFARIGVPVFVADIKGDLSGIGAAGNQSDKLMERLGAIGITDYTPRANTVVFW
                     DVFGEQGHPVRATISDMGPLLIARLLNLNDTQTGVLTLVFKVADDNGMLLLDLKDLRA
                     MVQYVGENAKSFTTEYGNISTASIGAIQRNLLTLEEQGGDVFFGEPMLDIADLMQTDA
                     DGRGVINVLAADKLYHSPKLYSTFLLWMLSELFEQLPEVGDPDKPKMVFFFDEAHLLF
                     DDAPEALVEKIEQVVRLIRSKGVGVYFVTQNPLDVPDEVLGQLGNRVQHALRAFTPRD
                     QKAVKTAADTMRPNPAFDAAAAITELGVGEALISFLDEKGRPQVTERCNVIAPDSRLG
                     PLQPAERQAAITGSVVYGHYEKAVDRESAYELLKASAATKAAVEAGREAAKEVGGEDT
                     GSMVSDILFGSTGPRGGKRDGLVHIAAKTVTRTIGSSLGRQIVRGILGSLLGGRR"
     assembly_gap    7046..7145
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            7368..8093
                     /locus_tag="P5537_13860"
     CDS             7368..8093
                     /locus_tag="P5537_13860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HRV79172.1"
                     /translation="MAGHSKWANIQHRKGRQDEKRGAAFSKLAKEITVAAKMGGGDPG
                     FNPRLRLAVDKAKGVNMPKDKIDNAIKKGTGELEGVSYEEIRYEGYGIGGSAVMVDCL
                     TDNKTRTVADVRHAFSKYGGNMGTDGCVSFQFKHCGQLLFAPGTSEDALMEAALEAGA
                     EDVLTNDDGSIEVITGPWEFTTIKEALEKAGFTAEFGEVTMKPENVIELAGDEAVRMQ
                     KLLDALEGLDDVQEVYTSAEIDE"
     gene            8159..9040
                     /locus_tag="P5537_13865"
     CDS             8159..9040
                     /locus_tag="P5537_13865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HRV79173.1"
                     /translation="MPTPPLLTRLTPLLFVLLWSTGFIGAKYGLPYAEPLTFLSSRYV
                     LVIGLMSLLALAMRAPWPASPREALHIGVTGLLVQALYLGGVFMSIHRGLPAGISALV
                     VGMQPLLTAALAGALLGERVSVRQWAGLALGFGGVALVVGSKANVDGVDGGALMHMLV
                     PALAALLGITAGTLYQKRFCPRFDLRTGSVMQFLPSLVITLLVASQTETLRIEWTGDF
                     VFALGWLVLVLSIGAISLLNLLIRSGSAVNVASLFYLTPPTTALIAWAMFDETLSALA
                     IVGMTIAVAGVWLARKG"
     gene            9076..9393
                     /locus_tag="P5537_13870"
     CDS             9076..9393
                     /locus_tag="P5537_13870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HRV79174.1"
                     /translation="MLMTTTSNLDGQPIRQYLGVVNGEAIIGANLFKDMFASIRNVVG
                     GRAGSYERTLADARRIAMEEMEEAAQKLGANAVIGIDVDYEVLGADNGMLMVCVSGTA
                     VKI"
     gene            9390..9941
                     /gene="ruvC"
                     /locus_tag="P5537_13875"
     CDS             9390..9941
                     /gene="ruvC"
                     /locus_tag="P5537_13875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008821 - crossover junction
                     endodeoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HRV79175.1"
                     /translation="MSAAASAHVVTRILGLDPGLRITGFGLVDQLGNQLRYVASGCIR
                     TQDGELPGRLKTLLDGVREIVDTYRPDVVAVEKVFVNVNPQSTLLLGQARGAVICGAV
                     SCDLPVAEYTALQVKQSVVGYGKAHKEQVQHMVQRLLALDASPGPDAADALACAICHA
                     HGSRGLGAVPGIGTRRRAGRILG"
     gene            10072..10147
                     /locus_tag="P5537_13880"
     tRNA            10072..10147
                     /locus_tag="P5537_13880"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10105..10107,aa:Lys,seq:ctt)
BASE COUNT         1489 a         3542 c         3490 g         1528 t
ORIGIN      
        1 gcggacggca gcctggtgcc gccgctcgac ttcatcccct tcgccgagga gtgcgggctg
       61 atctccgcga tcggggcgcg cgtgctgctg cgcgcctgcc acgacgccgc ggcctggatg
      121 cggcgcggcc ttcggctgcg ggtggcggtg aacctgtcgc cgatgcagtt ccgcgccccc
      181 gacctgctcg agcgcgtgtg cgaggcgctc gatcgcagcg gcctgccgcc cggcctgctg
      241 gagctcgaga tcaccgaggg cgcgctgatg gaggacgacg cgcgcacccg cgccacgctg
      301 gccgcgctgc gcgggctcgg catcggcatc gcgctcgacg acttcggcac cggttattcg
      361 tcgctgagct acctcaagcg cctgccgctg ggccggctca aggtcgaccg cagcttcgtc
      421 gccggcctcc ccgacgacgc cgacaacctc gccatcgtgc gcgccatcct cgccctcgcc
      481 cgccatctcg gcttccgcat caccgccgag ggcgtggaga ccgcggcgca ggcggccctg
      541 ctcgccggcc tggaggccga cagcctgcag ggctatctgt tcagccgccc ggtcgcggcg
      601 gcgcagatcg aggcgctcgc ggcgcgcagc tggaccatcg gcgcacgcga tcgcgccgat
      661 tgaagcgcgg ccggggatcg ctcaaggcag cccaccgcgg ggagcggtct gccgatactc
      721 agctggccgg ccgacgcaga ttgcgcgcca gcccgagcag cgacgcgccc ggcttgaggc
      781 ccgcgcgatg acaacgctcc acatcgatct cgaaggccag gcgcttgccc tcggcgacga
      841 tcaccaccgc agcctgttgg ggcggcggcg cgtcggtcac ggtcagtacc ggggcgtcgc
      901 cgagcagcgc ggagatctgc ggcaggctgg aagcctcgtt cgcgccgacg tagagcagat
      961 cgcagtcgcg gatcgccgac agcgaccgca ggcgcgccac cgtcacgctg cgcccgtgca
     1021 gggtcttgcc ctccagccgg cgcatcgcct cggccacgcc ctcgtccccg taggcgcaga
     1081 agttgaaggt cgtgcgcgcc gccgccggcc acagggtgag cgcggcgaag ttgtacgcgt
     1141 aggtggcctt gagctcgagc tcgggcagcg cctgcgcgag cacgcccggc gaagaccaca
     1201 gcgcgagcag gaagaggagg actctcggct tcaaagcgcg tacccgatct gcagccagac
     1261 gctgcgcccg tccatgcgca ggccgtcctg cgccacgtcc ccgggccgcc agtcgaagcc
     1321 cgacaccgtc tcgtagtcgc ggtcgaacag gttgcgcacg ctcagcgagg ccgacaggcc
     1381 gtgccagtcg cgttcggtgg tcagcgtgag gtgggcgagc gcgtgcccgc cgagcatgcg
     1441 gcgctcgcgg gtcaggcgcg gcccgaggta ctgcgcctcg acgccggcgc gcagcgcctc
     1501 gcccggcagc aggaaggtgt aggcgagctt gccgagcagg tcgggcgaat tgaccgcgtc
     1561 gcgcccctgg acgtcgcgcg agcgctgcca ggccacgctg gcgcgcacgc gcgcaccgcg
     1621 ctcccacagg tgctcgatct cggcctcgac gccgtgcgcg cggctgctgc cggcgggcac
     1681 gtagtcctcc agtgcgtcgt cgtagacgag caggtcgctg cgccggtagc ggtagagcgc
     1741 gccggtgaag cgcgtgtgcg ccgcgagctg gcgctgcagc acgagctcgg tggcggcgac
     1801 gtactcgggc accgcggtgt cgtcggacgt ccagcggtcg ttggcgttgg gcatcttgaa
     1861 ggcctcgctg tacgaagcct tccaggtggt tgccgggtcg ggttgccaga tcagcgccac
     1921 gcgcgggctg aggttgccgt cgaggtcgtc ggcgtcgtcg tggcgcgcgc cgaggttgag
     1981 cgtccatcgg tcgctcaggc ggtagtcgtc agcgatgtag aggctgacgg tgcggcggga
     2041 gcgctcgccg tcgtcgcggt aggtgacctc accgtccggc gcgagaaagc gacgccggaa
     2101 cgactggcgg tggtcgtcgc gcaattcggc cccgaacacc agcgtgtggt cggtgaacca
     2161 gcgcccgacg aatttctggt cgaagcgcca ccacgctccg gtgaagtccc gcacgccgta
     2221 cttctcgccg tcgtcgtact cgccgtcctc gttcagggcg tattcgcgct ggttccagta
     2281 gccatagcgt ccgagcatca ggctgctcga cgaggacagc tggaggccga ggtcggtctc
     2341 gtggcgcacg ccgaggaagg cgctctcgtc gcgcgtcggg aacggcgtgt tgaaggcggt
     2401 gtatgcggac gggttcgtgg ggacgctctt ctcgcgctcc acccacgccg cctgcaccgt
     2461 ccacccgccc cacgccaact tgccgaacac gcgctggctg cgctcgccgt cgagtccctc
     2521 ggccacgcca tggttggtcg cgggcgtgtc gtaggcgggg aagtacaggt tgcgcccgtc
     2581 gacgtcgagc gtggaggccg agagcagcac ctcggcgcca ttgtcgaggc gcttgcccca
     2641 ggtggcgcgc tggcggctgc cgccacggct ggagatctcg gcggaaacgc gcgcgccgtc
     2701 gaagtcgcgc ccgcgccgcg tgacgacgtt gaggatgccg agcagcgcgt tgttgccgta
     2761 ggtgaccgag ccggtgccgg gcacgtactc gacgcgctcg accagctcca ggtcgatcag
     2821 gccggactcg tcgatgtagg cctggtcgaa gaggttgtcc tgcaccgcgt agccgtcgat
     2881 cagcaacatg acccggccgg cgtagtcctc gacgtcgccg aagccgcgcc cgcccatgta
     2941 gtgataggta cgctcgtcgg tggtgtacag gccgcgcatg ctgttgatga cttcggcaag
     3001 cgtgcggtag ccataggcgc ggatgtcgtc ggcggtgacg atggccaccg cggcgggcga
     3061 gtcgctcacc tggcgcgcca gccgcgaggc ggagacgaag tcgcgccgca gcagctcctc
     3121 gaagggcagc gcggtgaggt cgtcctgcgc gatgccctcc ccgggctgga acgcgagcag
     3181 cacgcccagg ccgagcacga cgcccctgaa acgacgacaa ctcacgacct tttccgctcc
     3241 ctgctccgtt cgtgcatatt ggcctacgcc caaatcgggt atcgtatcag gctggtcctg
     3301 cgcccgacct ttcccccgat gaaaaccctc gaacacatcc cgctcaacgg tgaactgccc
     3361 agcccgaaag gtgtcgcgct ggccatcctc gaactgtgcc gcaaggacga cgcgaccatc
     3421 gccgaggtgg cgcgcatcgc acagaccgac ccggcgctgg ccagccgtct gatccgccag
     3481 gccaactccg cggcgcacgg tgcgggccgc ccggtggcct cggtcaccga ggcgatcatg
     3541 cgcctgggca tgggcacggt gcgcaacctc gcgctcggct tctcgctggt ggaccagtac
     3601 cagaacggcc cctgcgggca gttcgactac caaggcttct ggtcgcattc gctgctgatg
     3661 gggctggcga tgcagcgctt cagcaacatg accggcgccg gctcgagcga ggagctgttc
     3721 gcctgcggcc tgctcgccca ggtgggccgg ctctccctcg ccaccgtcta tccgatggaa
     3781 tacagccgcc tgctcgacgg ccagggcgcc gccgcgccca atctggtcgc cctcgagcag
     3841 gagcacctgc agaccgatca caacgagctc accgccgccc tgctcggcga gtggggcatc
     3901 cccggcgcac tgatcgagcc gatctaccac cacgaggagc ccgagcgctc cggcttctcg
     3961 cccggctcac gccccttcca gctggtgcat ctgttctacc tcgcccgccg cgtcgccgac
     4021 ctcgggctcg ccggcgagag cgagcgcaac gcctgcaccg ccgagttgct gctgctcggc
     4081 ggcaagatcg gactggacgc cgagcagctc ggcgccaccg tggacgacct ggtgctgcag
     4141 tggcgcgagt ggggcgagct gctgcgcgtg ccggcctcgg cgctgccctc gttcgcgcac
     4201 atgtcggcgg cgcatgcgat gcgcgacgag ggcgccggcg gagcggctgc actgcgcgta
     4261 ctgctcgtcg atgacgaccc caccacgcgc tgcatgatgg agggcgtgct cgcgggcgcg
     4321 ctcggccact cggtggtgtg cgccaacaac ggccgcgagg cgctcgcgct ggcggtcgag
     4381 acccagccgc agatcgtcat caccgactgg atgatgccgg gcatggacgg gctcgacctc
     4441 gcgcgcgcgc tgcgcgcgac cgagtggggg cagacgatgt acctgatcat gctcaccggc
     4501 ctggagaccg aggacgaggt gagcgcggcc ttcgaggccg gggtggacga cttcctggtg
     4561 aagccggtca acgtgcgcac cctgcgcgcg cgcctgcgcg cagcctggca ctacgtgcag
     4621 ctgctcgacg cctgggagcg cgaccgcgcc cagctcaagc agttcgccgc cgagctggcg
     4681 atcagcaacc gccgcctcgc ccacgcggcg atgaccgacc tgctcaccaa cctgcccaac
     4741 cggcgctcgg gcatgaacgc gctcgccaag gcctgggccg ccgccagccg cttcgagcag
     4801 ccgctgtcgg tgatgatgct cgacatcgac cacttcaagc gcatcaacga cggccacggc
     4861 cacgcggcgg gcgacaccgt gctgcgcgac gtcgcccagg ccatccagca gtcggcgcgc
     4921 aaggacgaca gcgtgtgccg catgggcggc gaggaattcc tcgtgatctg cccgaacacc
     4981 gacctcaagg cggcgatcca ggccgccgag cgcctgcgcc gcatggtcga gcgcctgtgc
     5041 atccgggctg gcgacaccga gatccggacc tcggtgagca tcggcgtagc cacccgcgag
     5101 gtcggcatga ccgagaccga cgcgctcgta aatgccgccg accgcgcgct ctaccgcgcc
     5161 aagcaggccg gccgcaaccg cagctgcgtg gtcgtgcagg ggcagatgcg gtgttttccg
     5221 tgaggcgtga ggcttgaggc gtgaggcgta aggggctggg ctgcggggag ccgctgaacc
     5281 gccgattcgc gccttgcggc gctcgtacat gaaccatcga tgctgcggag ccccgggtgc
     5341 gcggctgccc tcgcgtcctc agcgccgccc gccgagcagc gagcccaata tcccgcgcac
     5401 gatctgccgc ccgaggctgc tgccgatggt gcgcgtgacc gtcttggcgg cgatgtgcac
     5461 caggccgtcg cgcttgccgc cgcgcggacc ggtggagccg aagaggatgt cgctgaccat
     5521 gctgccggtg tcctcgccgc cgacctcctt cgccgcctcg cgcccggcct cgacggcggc
     5581 cttggtggcg gcgctggcct tgagcagttc gtaggccgac tcgcgatcga ccgccttctc
     5641 gtagtgcccg tagaccaccg agccggtgat cgccgcctgg cgctcggcgg gctgcagcgg
     5701 gccgaggcgg gaatcgggcg cgatgacgtt gcagcgctcg gtgacctggg gccggccctt
     5761 ctcgtcgagg aaggagatca gcgcctcgcc cacgcccagc tcggtgatcg cggcggccgc
     5821 gtcgaaggcg gggttgggcc gcatggtgtc ggcggcggtc ttcaccgcct tctggtcgcg
     5881 cggcgtgaag gcgcgcagcg cgtgctggac acggttgccg agctggccca gcacctcgtc
     5941 cggcacgtcg agcgggttct gggtgacgaa gtacacgccc acgcccttgg agcggatcag
     6001 gcgcaccacc tgctcgatct tctccaccag cgcctcgggg gcatcgtcga acagcagatg
     6061 tgcctcgtcg aagaagaaca ccatcttcgg cttgtccggg tcgcccacct cgggcaactg
     6121 ctcgaagagc tcggacagca tccacagcag gaaggtggag tagagcttgg gcgagtggta
     6181 gagcttgtcg gcggccagca cgttgatcac gccgcggccg tcggcgtcgg tctgcatcag
     6241 gtcggcgatg tcgagcatcg gctcgccgaa gaagacgtcg ccgccctgct cctcgagcgt
     6301 cagcaggttg cgctggatgg cgccgatcga ggcggtggag atgttgccgt actcggtggt
     6361 gaagctcttc gcgttctcgc ccacgtactg gaccatcgcg cgcaggtcct tgaggtcgag
     6421 cagcagcatg ccgttgtcgt cggcgacctt gaacaccagc gtcagcacgc cggtctgggt
     6481 gtcgttgagg ttgagcaggc gcgcgatcag cagcggcccc atgtccgaga tggtggcgcg
     6541 aaccgggtgg ccctgctcgc cgaacacgtc ccagaacacg acggtgttgg cgcgcggggt
     6601 gtaatcggtg atgccgatgg cgcccaggcg ctccatgagc ttgtcggact ggttgccagc
     6661 ggcgccgatg ccggagaggt cgcccttgat gtcggcgaca aagaccggca cgccgatgcg
     6721 ggcgaaggac tcggcgagct tctgcagggt caccgtcttg ccggtgccgg tggcgccggt
     6781 gatcaggccg tggcggttgg ccaggcgcgg cagcaggcag atatccttga actggtcctt
     6841 gtcgtgcgca cgcgcgatca gcatcgggtc ggccatttca tgctcctcgg gaatcggttc
     6901 ggaatgcccc gagtttagca gcccggcggg caggctcgtg cggcgcctcc gcgcacgaca
     6961 aggcccgtcg ccaccgcacc gccgtcttcg cggctgccgc cgctcctaca tcgggcctgc
     7021 ggagccgcgc tgttcctgta ggagcnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7081 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7141 nnnnncggct gccgccgctc ctacatcggg cctgcggagc cgcgctgttc ctgtaggagc
     7201 gccggcaggc gcgaacgcag cgcctccgcg cacgacaacg cccatcgcca ccgcaccgcc
     7261 gtcttcacgg ctgccgccgc tcctacagga accgggcggc gcggcgcacg cggcgggcgc
     7321 tataatgcgc gcctcttcaa tcgctcgggc agcacagagg ttccaatatg gcgggtcact
     7381 cgaaatgggc caacatccag caccgcaagg gtcgtcagga cgaaaagcgc ggtgctgcat
     7441 tctccaagct ggcgaaggag atcaccgtcg ccgccaagat gggcgggggt gacccgggct
     7501 tcaacccgcg cctgcgcctg gcggtggaca aggccaaggg cgtcaacatg cccaaggaca
     7561 agatcgacaa cgcgatcaag aagggcaccg gcgagctcga gggcgtgagc tacgaagaga
     7621 tccgctacga aggctacggc atcggcggct cggccgtcat ggtcgactgc ctcaccgaca
     7681 acaagacccg caccgtggcc gacgtgcgcc acgccttctc caagtacggc ggcaacatgg
     7741 gcaccgacgg ctgcgtgtcc ttccagttca agcactgcgg ccagctgctg ttcgcccccg
     7801 gcaccagcga ggacgcgctg atggaggccg cgctcgaggc cggcgccgag gacgtgctca
     7861 ccaacgacga cggctcgatc gaggtgatca ccggcccgtg ggagttcacc accatcaagg
     7921 aagcgctgga gaaggccggc ttcaccgccg agttcggcga ggtcacgatg aagcccgaga
     7981 acgtcatcga gctcgccggc gacgaggccg tgcgcatgca gaagctgctc gacgcactcg
     8041 aaggcctgga cgacgttcag gaggtgtaca cctccgccga gatcgacgag taagttcccc
     8101 gatctgcccc aggaaagcgg cgcccggcgc cgcttttttg tttgatggac ccgacgcgat
     8161 gcccaccccg cccctgctca cccgcctgac gccgctgctg ttcgtgctgc tgtggagcac
     8221 aggcttcatc ggcgccaagt acggcctgcc ctacgccgag ccgctcacct tcctgagcag
     8281 ccgctacgtg ctggtgatcg gcctgatgag cctgctcgca ctggcgatgc gcgcgccctg
     8341 gccggccagc ccgcgcgagg cgctgcacat cggcgtcacc ggcctgctgg tgcaggcgct
     8401 ctatctgggc ggcgtgttca tgtcgatcca tcgcggcctg ccggcgggca tctcggcgct
     8461 ggtggtgggc atgcagccgc tgctcaccgc cgcgctcgcc ggcgcgctgc tcggcgagcg
     8521 ggtctcggtg cggcagtggg ccgggctcgc gctcggcttc ggcggcgtgg cgctggtggt
     8581 cggcagcaag gcgaacgtgg atggagtcga tggcggcgcg ctgatgcaca tgctcgtgcc
     8641 ggcgctggcg gcgctgctcg gcatcaccgc cggcaccctg taccagaagc gcttctgccc
     8701 gcgcttcgac ctgcgcaccg gctcggtgat gcagttcctg cccagcctgg tcatcacgct
     8761 gctcgtcgcc agccagaccg agaccctgcg catcgagtgg accggcgact tcgtgttcgc
     8821 gctcggctgg ctggtgctgg tgctgtcgat cggcgcgatc agcctgctca acctgctgat
     8881 ccgcagcggc agcgcggtca atgtggcgag cctcttctac ctgaccccgc cgacgaccgc
     8941 gctgatcgcc tgggcgatgt tcgacgagac cctttccgcg ctcgccatcg tcggcatgac
     9001 gatcgccgtc gccggtgtgt ggctggcgcg caagggctag aatcggagct cttccccacc
     9061 ccgaaggaga atgccatgtt gatgaccacc acctcgaatc tcgacggcca gccgatccgc
     9121 cagtacctcg gcgtggtcaa tggcgaggcc atcatcggcg ccaacctgtt caaggacatg
     9181 ttcgcctcga tccgcaacgt ggtcggcggc cgcgcgggca gctacgagcg taccctcgcc
     9241 gacgcccgtc gcatcgccat ggaagagatg gaagaggccg cgcagaagct cggcgccaac
     9301 gcggtgatcg gcatcgacgt cgactacgag gtcctcggcg ccgacaacgg catgctgatg
     9361 gtgtgcgtca gcggcaccgc ggtgaagatt tgagcgctgc cgcgagcgcg cacgtcgtca
     9421 cccgcatcct cggcctcgac cccgggctgc gcatcaccgg cttcggcctg gtggaccagc
     9481 tcggcaacca gctgcgctat gtcgccagcg gctgcatcag gacgcaggac ggcgagctcc
     9541 ccggccgcct caagaccctg ctcgacggcg tgcgcgagat cgtcgatacc taccgccccg
     9601 acgtggtcgc ggtcgagaag gtcttcgtca acgtcaaccc gcagtccacc ctgctgctcg
     9661 gccaggcgcg cggcgcggtg atctgcggcg cggtgtcctg cgacctgccg gtggccgaat
     9721 acaccgcgct gcaggtcaag cagtcggtgg tcggctacgg caaggcgcac aaggagcagg
     9781 tccagcacat ggtgcagcgc ctcctcgccc tcgacgccag ccccggcccc gacgccgccg
     9841 acgccctcgc ctgcgcgatc tgccacgccc acggctcgcg cggcctcggc gccgtcccgg
     9901 gcatcggcac ccgccgccgc gcgggccgca tcctgggctg aacagcgccg ctcctccccg
     9961 aaccccgctg cagcgccctg tagggcgaga aatctgttgc gctgcgcaaa actcgcgcgt
    10021 atgatgcgcg ctcttcgatc gggcaccaat ccgatccgcc gcaaggcaat ggggggtata
    10081 gctcagttgg tagagcagtt gactcttaat caattggtcc taggttcgag tcctagtgcc
    10141 cccaccaac
//
LOCUS       DAOTIN010000118         9872 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_8159_length_9872_cov_9.466232, whole genome shotgun sequence.
ACCESSION   DAOTIN010000118 DAOTIN010000000
VERSION     DAOTIN010000118.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 9872)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 9872)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9872
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_8159_length_9872_cov_9.466232"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(124..1524)
                     /locus_tag="P5537_13885"
     CDS             complement(124..1524)
                     /locus_tag="P5537_13885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79176.1"
                     /translation="MDQPRTLDYTPAGVLAGGGNPVVGLEAATATLRALYKPGSPKTE
                     VAGLHVVSSFDDALREAVERSAPIGVRASGDPASGHDHAWWVRWLAGVRDAWMAVCDG
                     YWCLSPSNSVAGSEATRLRLASAVVEALKWSACDRFGPDEVLWARIGQLFAASPEARD
                     SVVGGDVHNIGREYLRAVAHYSINLDQVELEMGIALGHVVDVCLPFLSLDRRAADVPQ
                     YVVIPEEGTIPARQMGKHREGEWRFAPWAAGELLAEFSRQLARSIVPAPFGRLPLEHA
                     RAAVEYLRMQWSKAPPVRTRRRYLQDASADIARGLHACTAVIGGQPLPVPRNWRVVDF
                     SRSGLQIVANSDPTRAWPDIGELLGIHFVDGDGWQLGIVRRLRMWATHAGLGIELLAR
                     SPSLGVVDDGRNSVDGILCDVPSKGEALRVLLPANAPALAEPVFVKTSGSVCKLRSLG
                     VLRREAGYQLQVFQVL"
     gene            1736..2530
                     /locus_tag="P5537_13890"
     CDS             1736..2530
                     /locus_tag="P5537_13890"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011238317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004799 - thymidylate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HRV79177.1"
                     /translation="MRQYLDLMRHVLEHGDPKTDRTGTGTLSVFGWQMRFRLQDGFPL
                     LTTKKLHTRSIIHELLWFLQGDTNIRYLKENGVSIWDEWADADGELGPVYGKQWRSWE
                     TADGRTVDQLARVVDSIRHNPDSRRHLVSAWNPGEVDDMALPPCHALFQFYVAGGRLS
                     CQLYQRSADIFLGVPFNIASYALLTHMVAQVCELEPGDFIWTGGDCHLYSNHLEQARE
                     QLGREPRALPTLRLNPAVRDLFGFRFEDIALEGYDPHPHIKAPVAV"
     gene            2527..3021
                     /locus_tag="P5537_13895"
     CDS             2527..3021
                     /locus_tag="P5537_13895"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004312324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HRV79178.1"
                     /translation="MNRPEIVLIAAVARNGTIGRDNELPWRLRADLQHFRALTLGHPI
                     LMGRKTWESLGRPLPGRRNLVVSRDPEFRAEGAECFADPATAIAAVGGAPTLFVIGGA
                     QLYAQLLPHADRLELTEVHADIDGDAHFPAFDPAQFVEECREAHHADADNAFDFDFVR
                     YRRR"
     gene            complement(3116..5359)
                     /locus_tag="P5537_13900"
     CDS             complement(3116..5359)
                     /locus_tag="P5537_13900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004375523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine/lysine/ornithine decarboxylase"
                     /protein_id="HRV79179.1"
                     /translation="MRFHFPIIIIDEDFRSENTSGLGIRALAKAIEEEGMEVLGVTSY
                     GDLTSFAQQQSRGSTFILSIDDEEFSSPEAAAKAIADLRAFVEEIRFRNADIPIFLHG
                     ETRTTRHIPNDVLREMHGFIHMFEDTPEFIARYVVREAKNYLESLAPPFFRALTHYAA
                     DSSYSWHCPGHSGGVAFLKSPVGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAA
                     SERNAARIFNCDHLYFVTNGTSTSNKMVWHTTVAPGDIVVVDRNCHKSILHSIIMTGA
                     VPVFLTPTRNHYGIIGPIPLEEFSIENIQKKIEANPFAREAKNKKPRILTITQSTYDG
                     VVYNVEAIKDLLDGEIDTLHFDEAWLPHAAFHDFYGDYHAIGADRPRCRESMVFATQS
                     THKLLAGLSQASQILVQDSQTRKLDRDIFNEAYLMHTSTSPQYAIIASCDVAAAMMEA
                     PGGTALVNESLSEAVEFRRAMRKVDAEFGEDEWWFQVWGPEYLAEEGIGHRADWTLKA
                     GERWHGFGNLAEGFNILDPIKATIITPGLNMDGDFAEHTGIPAAIVTKYLAEHGIIVE
                     KTGLYSFFIMFTIGITKGRWNTMVTELQQFKDDYDRNQPLWRVMPEFIAKHPRYERVG
                     LKDLCDQIHSFYKANDVARLTTEMYLSDMVPAMKPADAFAKMAHREIERVVLDELEGR
                     VTAMLVTPYPPGIPLLIPGERFNATIVRYLKFARDFNARFPGFETDIHGLVKGEDGRY
                     HVDCVKG"
     gene            complement(5509..6075)
                     /gene="dcd"
                     /locus_tag="P5537_13905"
     CDS             complement(5509..6075)
                     /gene="dcd"
                     /locus_tag="P5537_13905"
                     /EC_number="3.5.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011111249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008829 - dCTP deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0009394 - 2'-deoxyribonucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dCTP deaminase"
                     /protein_id="HRV79180.1"
                     /translation="MSIKSDKWIRRMAEQARMIEPFAPELVRSNESGRIVSYGTSSYG
                     YDVRVANEFKIFTNINSTIVDPKDFDARNFVDFTGDVCIIPPNSFALARTVEYFRIPR
                     SVLTVCLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPAKIYANEGVAQMLFF
                     ESDEVCETSYKDRGGKYLGQTGVTLPKI"
     gene            complement(6253..7344)
                     /gene="apbC"
                     /locus_tag="P5537_13910"
     CDS             complement(6253..7344)
                     /gene="apbC"
                     /locus_tag="P5537_13910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster carrier protein ApbC"
                     /protein_id="HRV79181.1"
                     /translation="MSLDQQTVTEALKQVIDPNTGKDFVAGRSIRNLSVQGGEVRFDV
                     ELGYPAKSQHEPIRALLSEAVAKLAGVERVAVTVSSKVVAHAVQQGVKLLPGVRNIIA
                     VASGKGGVGKSTTAVNLALALSAEGARVGLLDADIYGPSQPQMLGIGDQRPVSEDGKT
                     MIPLQAFGLQAMSIGFLIDPDTPMVWRGPMATQALNQMLKDTAWDDLDYLVIDMPPGT
                     GDIQLTLSQSVPVTGAVIVTTPQDIALLDARKGVKMFEKVGVPILGVVENMSIHICSK
                     CGHEEHIFGQGGGEKMCADFKVPFLGALPLDIQIRTEADSGAPTVVADPDGRIASIYK
                     QIARKVAVRIAERSKDMTHKFPNIVFKSA"
     gene            7521..8120
                     /locus_tag="P5537_13915"
     CDS             7521..8120
                     /locus_tag="P5537_13915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015288 - porin activity [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HRV79182.1"
                     /translation="MTSRNTRRKSAFPTALASAAVLASLLAACATPGGGSGAEPDAIH
                     RHALVRTAPPAPSWSALHEQLGKAAAGIAGVELGKVDTAGFHVQIPVADGFASGSAQI
                     RPALGRALDALAPALAAEPGVAVRVLGHTDSQGSEMVNLRLSISRAEAVVAWLQERGI
                     ALDRLTADGRGEADPLTSNATEEGRVRNRRIELILSPMP"
     gene            8198..>9872
                     /gene="metG"
                     /locus_tag="P5537_13920"
     CDS             8198..>9872
                     /gene="metG"
                     /locus_tag="P5537_13920"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004312332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HRV79183.1"
                     /translation="MSRKLLVTNALPYANGDIHLGHLVGYIQADIWVRFQRMRGHSVH
                     YVCADDTHGTPVMLRAEKEGLTPEQLIERVHGEHLRDFTAFGVAFDNYHSTHSVENRF
                     YAEDIYGKLKSGGLIDTRSIEQYYDPVKEMFLPDRFIKGECPKCGAADQYGDNCEACG
                     AAYAPTELKNPYSAVSGAKPVLKTSEHYFFRLSDERAVAFLREWTRGTNAAGERRLQA
                     EAANKMKEWLGEEGENKLSDWDISRDAPYFGFEIPGAPGKYFYVWLDAPIGYLASFRN
                     LAAKRAAAGEHIAVEDYTDASRAAAAGTEMVHFIGKDILYFHALFWPAMLKFAGYATP
                     SRLCVNGFLTVDGAKMSKSRGTFITAHSYIAQKLNPEWLRYYFAGKSNGTMEDVDLNL
                     DDMIAKVNSDLVGKFVNIASRCAGFIGKRFDGRLGEADAAACAEFATAWAEGRVANAY
                     EERDYGRALREIMRLADLANQYVNDHKPWELAKQEGQEARLHAVCSTALTMFRDLTRY
                     LKPVLPALAAQVEAFLAIPAMDWQGDWAPLPAGHAIQAYSHLMTRVERKQ"
BASE COUNT         1669 a         3408 c         3226 g         1569 t
ORIGIN      
        1 cctgcaggaa ccgctgcatt gaagtccgca gtgcagacgg gcgagaatgc ggcgcacagg
       61 cggcgattcg ctcaaacgct ggcggtctgc gggcacggag cccggtggcg accaccgagg
      121 gactcaaagg acctggaaga cctgcagttg atagcccgct tcgcgacgca ggacgcccag
      181 tgagcgcaac ttgcagaccg accctgaagt ctttacgaag accggctcgg cgagggcagg
      241 ggcgtttgca ggcaggagga cgcgcaaagc ctcccccttg cttggaacgt cgcacaggat
      301 cccgtcgaca ctgttgcgac catcatcgac gaccccgagc gaaggcgatc gtgcgagcag
      361 ttcgatgccc aggccggcat gcgtcgccca catgcgcagt cgccgcacga tgccaagctg
      421 ccaaccgtca ccatcgacga aatggatgcc gagcagttct ccgatatctg gccaggcccg
      481 cgttggatcg ctgttggcca cgatctgcag cccgctgcga ctgaagtcga ccaccctcca
      541 gttccgcggc accggaagag gctgcccgcc aatgacggca gtgcatgcat ggagcccacg
      601 cgcgatgtcc gcgctcgcgt cctgaaggta tcggcgccga gtccgcaccg gcggtgcctt
      661 cgaccactgc atgcgcaggt attcgacggc ggcacgtgca tgctcgagcg ggagacggcc
      721 gaagggtgca ggtacgatgg agcgcgcgag ttgcctggag aactcggcca gcaactcgcc
      781 cgccgcccag ggcgcgaaac gccactcccc ttcccggtgc tttcccatct gccgggccgg
      841 gatggtgccc tcctccggaa tcacgacata ctggggcaca tcggcagcac ggcgatcgag
      901 cgacaggaac ggcaggcaga catccacgac gtggccgagc gcgatgccca tctcgagttc
      961 gacctggtcg agattgatgc tgtagtgggc gaccgcgcga agatactccc gaccgatgtt
     1021 gtggacgtcc ccaccgacga cgctgtcgcg ggcctcggga gacgcggcaa agagctggcc
     1081 gatccgcgcc cacagcacct cgtcgggacc gaagcggtca caagcggacc atttcaaggc
     1141 ctcgaccacg gcgcttgcca gccgcaggcg ggtcgcctcc gatccggcca ccgaattcga
     1201 tggggaaaga caccagtagc cgtcgcacac cgccatccag gcgtcacgca caccggcaag
     1261 ccaacgcacc caccatgcgt ggtcatgccc cgaagcggga tcgcccgatg cgcgcacccc
     1321 gatcggcgcg gagcgctcga ctgcctcgcg caaggcatcg tcgaagctgg acacgacgtg
     1381 cagccctgcg acttcggtct tcggactacc cggcttgtac aacgcccgca aggttgccgt
     1441 cgcagcctcg agccccacaa ccggattccc gccgccggca agcacgccgg cgggagtgta
     1501 atcgagcgtt ctgggctgat ccaaaggcca ttctccgcac aagacgcgcc agcgcttccc
     1561 cggatgggaa aagcgctcga gcacgcgacg tttcgccaca ttctgaacca gcgcggaagg
     1621 cggtgtccac cgcacagcca ccatgacgaa cgcgagatcg ggaggcgtcc gcgtcaccgc
     1681 agcccagccc cttgcctccg cacagtagaa tcacgccttt ttaccggaag cgagcatgcg
     1741 acagtacctc gacctgatgc gccatgtgct cgagcacggc gaccccaaga ccgaccggac
     1801 cgggaccggc acgctatccg tgttcggctg gcagatgcgc tttcgcctcc aggacggctt
     1861 tccgctgctg accaccaaga aactgcacac gcgctcgatc atccacgagc tgctgtggtt
     1921 tctgcaggga gacaccaaca tccgctacct gaaggaaaac ggcgtatcga tctgggacga
     1981 atgggccgac gccgacggcg aactcggccc ggtgtatggc aagcagtggc ggagctggga
     2041 aaccgcggac gggcgcacgg tcgatcagct cgctcgcgtc gtcgacagca tccggcacaa
     2101 cccggactcg cgccgccacc tcgtctcggc gtggaatccg ggcgaggtcg acgacatggc
     2161 cctgccgccc tgccacgcgc tgttccagtt ctacgtcgcc ggcgggcggc tgtcgtgcca
     2221 gctctaccag cgcagcgcgg acatcttcct tggcgttccc ttcaacattg cctcctatgc
     2281 gctgctaacc cacatggtgg cgcaggtgtg cgaactcgag ccgggcgatt tcatctggac
     2341 gggcggcgac tgccacctgt acagcaacca tctggagcag gcacgcgagc aactcgggcg
     2401 cgagccgcgc gccctgccca cgctgcgcct gaatcccgcg gtgcgcgacc tcttcggctt
     2461 ccgcttcgag gacatcgcgc tcgagggcta tgacccgcat ccgcacatca aggctccggt
     2521 ggcggtatga atcgacccga gatcgtcctc atcgccgcgg tcgcgcgcaa cggcaccatc
     2581 ggacgcgaca acgagctgcc gtggcggctc agggccgacc tgcagcattt ccgtgcgctc
     2641 acgctcggcc accccatcct gatgggacgc aagacctggg agtcgctcgg ccgtccgctg
     2701 cccggaagac gcaacctcgt cgtaagccgc gacccggagt tccgcgccga aggcgccgaa
     2761 tgcttcgccg accccgcgac cgcgatcgcc gccgtcggcg gggcgccgac gctgttcgtg
     2821 atcggcgggg cccagctcta cgcccagctg cttccccacg ccgatcgcct cgagctcacc
     2881 gaggtgcacg ccgacatcga cggcgatgcg cacttccccg ccttcgatcc ggcgcagttc
     2941 gtcgaggagt gccgcgaggc acaccacgcc gacgcagaca acgccttcga cttcgacttc
     3001 gtacgctacc gccggcgctg aagccgtcag gagcgccggc actgccaccg caacgaacga
     3061 agagggccgc atcacgcggc cctcttcgtt cgacgccccc cgcgccgcgc gagtctcagc
     3121 ccttcacgca atccacgtga tagcgcccgt cctcgccctt gaccaggccg tggatgtcgg
     3181 tctcgaagcc cgggaagcgc gcattgaagt cacgcgcgaa cttcaggtag cgcacgatcg
     3241 tcgcgttgaa gcgctcgccc gggatcagca gcgggatgcc cggcggatag ggcgtgacca
     3301 gcatcgcggt gacgcggccc tcgagttcgt cgagcaccac gcgctcgatc tcgcggtgcg
     3361 ccatcttggc gaaggcgtcg gcgggcttca tcgccggcac catgtccgag aggtacatct
     3421 cggtggtcag gcgggccacg tcattggcct tgtagaagct gtggatctgg tcgcacaggt
     3481 ccttgaggcc gacgcgctcg tagcgcgggt gcttggcgat gaactcgggc atcacccgcc
     3541 acagcggctg gttgcggtcg tagtcgtcct tgaactgctg cagctcggtc accatcgtgt
     3601 tccagcgccc cttggtgatg ccgatggtga acatgatgaa gaaggagtac aggccggtct
     3661 tctcgacgat gatgccgtgc tcggcgaggt acttggtgac gatcgccgcc gggatgccgg
     3721 tgtgttcggc gaagtcgcca tccatgttga ggcccggggt gatgatcgtg gccttgatcg
     3781 ggtcgaggat gttgaagccc tcggccaggt tgccgaagcc gtgccagcgc tcgcccgcct
     3841 tcagtgtcca gtcggcgcgg tggccgatgc cctcctcggc gaggtattcc ggcccccaca
     3901 cctggaacca ccattcgtct tcgccgaact ccgcatcgac cttgcgcatc gcgcggcgga
     3961 actccacggc ttccgacaac gactcgttca ccagcgccgt tccccccggc gcctccatca
     4021 tcgccgccgc cacgtcgcac gacgcgatga tcgcgtactg cggcgaggtc gaggtgtgca
     4081 tcaggtaggc ctcgttgaag atgtcgcggt cgagcttgcg ggtctgcgag tcctgcacga
     4141 ggatctgcga ggcctggctg aggccggcga gcagcttgtg ggtggactgg gtggcgaaca
     4201 ccatggattc gcggcagcgc ggacgatcgg cgccgatcgc gtggtagtcg ccgtagaagt
     4261 cgtggaaggc tgcatgcggc agccaggcct cgtcgaagtg cagggtgtcg atctcgccgt
     4321 cgagcagatc cttgatggcc tcgacgttgt acaccacgcc gtcgtaggtc gactgggtga
     4381 tggtgaggat gcgcggcttc ttgttcttcg cctcgcgcgc gaaggggttg gcctcgatct
     4441 tcttctggat gttctcgatc gagaactcct ccagcgggat cgggccgatg atgccgtagt
     4501 ggttgcgcgt cggggtcagg aacaccggca ccgcgccggt catgatgatc gagtgcagga
     4561 tggacttgtg gcagttgcgg tcgacgacga cgatgtcgcc gggggccacc gtggtgtgcc
     4621 acaccatctt gttcgaggtc gaggtgccgt tggtgacgaa gtacaggtgg tcacagttga
     4681 agatgcgcgc cgcgttgcgc tcggaggccg ccaccggacc ggtgtggtcg agcagctggc
     4741 cgagctcgtc gaccgcgttg cacacgtccg cgcgcaacat gttctcgccg aagaactgat
     4801 ggaacatctg ccccaccggg ctcttcagga aggcgacccc gcccgaatga cccgggcagt
     4861 gccaggaata cgaactgtcg gccgcgtagt gcgtcagcgc gcggaagaag ggcggcgcca
     4921 gcgactcgag gtagttcttc gcctcgcgca ccacatagcg cgcgatgaac tccggcgtgt
     4981 cctcgaacat gtggatgaag ccgtgcatct cgcgcagcac gtcgttgggg atgtgacgcg
     5041 tggtgcgggt ctcgccgtgc aggaagatcg ggatgtcggc gttgcggaag cggatctcct
     5101 cgacgaaggc gcgcaggtcg gcgatcgcct tggccgcggc ctcgggcgag gagaactcct
     5161 cgtcgtcgat cgacaggatg aaggtcgagc cgcggctctg ctgctgcgcg aaggaggtca
     5221 ggtcgccgta gctggtgacg ccgagcactt ccatgccctc ttcctcgatc gccttggcga
     5281 gcgcgcggat ccccagtccc gaggtgttct ccgagcggaa gtcctcgtcg atgatgatga
     5341 tggggaagtg gaatctcatc ctggtcgtct ccagcgggtc cgggcgggac gggtaaaacc
     5401 ggcagtgtac tccggcgaag attgcccgcg cgttaccgaa agtggttcaa gaaagcacaa
     5461 ggggccgtca ggcggccccg tggaagaagt cgtgcgaagc gaaggcgctc agatcttggg
     5521 cagggtgacg ccggtctggc cgaggtactt gccgccgcga tccttgtacg aggtctcgca
     5581 cacctcgtcc gactcgaaga acagcatctg cgccacgccc tcgttggcgt agatcttcgc
     5641 cggcagcggc gtggtgttgg agaactcgag ggtcacgtgg ccctcccact cgggctcgag
     5701 cggggtgacg ttcacgatga tgccgcagcg cgcgtaggtg ctcttgccca ggcacacggt
     5761 cagcacgctg cgcgggatgc ggaagtactc gaccgtgcgc gcgagcgcga aggagttcgg
     5821 cgggatgatg cacacgtcgc cggtgaagtc gacgaagttg cgcgcgtcga agtccttggg
     5881 gtcgacgatg gtcgagttga tgttggtgaa gatcttgaac tcgttcgcca cgcgcacgtc
     5941 gtagccgtag ctcgaggtgc cgtaggacac gattcgcccg ctctcgttgc tgcgcaccaa
     6001 ctccggcgcg aagggctcga tcatgcgggc ctgttcggcc atgcggcgga tccacttgtc
     6061 ggacttgatg gacatgggcg cgtcttccgg cgggttgcgg tgcgggcggc gggagccgtc
     6121 cgtgaaaagc cgcgtagtgt aaggcaggcg ggctgcgggc gaaaggcgca gctcgaacgg
     6181 agaacgaacg agccggcgag gccggcggct gccgcgcccg cccgccgcag cgggcgggcg
     6241 cggcgcgcgc gatcaggcgg acttgaacac gatgttgggg aacttgtgcg tcatgtcctt
     6301 cgagcgctcg gcgatgcgca ccgccacctt gcgcgcgatc tgcttgtaga tcgaggcgat
     6361 gcgaccgtcc ggatcggcga ccacggtggg cgcgccgctg tcggcctcgg tgcggatctg
     6421 gatgtcgagc ggcagcgcgc cgaggaaggg caccttgaag tccgcgcaca tcttctcgcc
     6481 gccaccctgg ccgaagatgt gctcctcgtg gccgcacttc gaacagatgt ggatgctcat
     6541 gttctcgacc acgccgagga tgggcacgcc caccttctcg aacatcttca cgcccttgcg
     6601 cgcgtcgagc agcgcgatgt cctgcggcgt ggtgacgatc acggcaccgg tcaccggcac
     6661 gctctgcgac agggtgagct ggatgtcgcc ggtgcccggg ggcatgtcga tgacgaggta
     6721 gtcgaggtcg tcccaggcgg tgtccttgag catctggttg agcgcctgcg tggccatcgg
     6781 cccgcgccac accatcgggg tgtcggggtc gatcaggaag ccgatcgaca tcgcctgcag
     6841 cccgaaggcc tgcagcggga tcatcgtctt gccgtcctcc gacaccgggc gctggtcgcc
     6901 gatgcccagc atctgcggct gcgagggacc atagatgtcg gcgtcgagca ggccgacgcg
     6961 ggcgccctcg gcggacagcg ccagcgcgag gttcaccgcc gtcgtgctct tgcccacgcc
     7021 gcccttgccc gaggccaccg cgatgatgtt gcgcacgccc ggcagcagct tgacgccctg
     7081 ctgcaccgca tgcgcgacca ccttgctgga caccgtcacg gcgacgcgct cgacgcccgc
     7141 aagcttggcc accgcctcgc tcagcagtgc gcggatcggt tcgtgctggc tcttcgccgg
     7201 atagccgagc tcgacgtcga agcggacctc gccgccctgc accgacaggt tgcggatgct
     7261 gcgcccggcg acgaaatcct tgccggtgtt ggggtcgatc acctgcttga gcgcctcggt
     7321 gacggtttgc tggtcaagac tcatcgcgtt ttcctcgaaa atcggtgcac ccgacgccgg
     7381 gtggaagcgg cagaatcata ccggagcgca gcgccggact cacccgcgtt ctgcgcaggg
     7441 ttactccgca ggccgggtcg cccgcccgca ggatccgttc gacgaacttc ccgcgcgccg
     7501 cacgccggcg ccccacgcac atgacttctc gcaacacccg ccgcaaatcc gcctttccca
     7561 cggccctcgc ctccgccgcc gtgcttgcca gcctgctcgc cgcgtgcgcc acgccgggtg
     7621 gcgggtcggg cgcagagccc gacgcgatcc accgccacgc cctcgtgcgc accgcgccgc
     7681 ccgcgccatc ctggagtgcc ctgcacgagc agctcggcaa ggccgccgcc ggcatcgccg
     7741 gggtcgagct cggcaaggtc gacacggcag gcttccacgt gcagattccg gtcgccgacg
     7801 gcttcgccag cggcagcgcg cagatccgcc ccgcactcgg acgcgcgctc gatgcgctcg
     7861 cgccggcgct cgccgccgag cccggggtgg cggtgcgcgt actcggacac accgacagcc
     7921 agggcagcga gatggtcaac ctgcgcctgt cgatctcacg cgccgaagcg gtggtggcat
     7981 ggctgcaaga gcgcggcatc gcgctcgacc gcctcaccgc ggacggccgc ggcgaggccg
     8041 atccgctcac ctccaatgcc accgaggagg gccgcgtgcg caaccgccgc atcgagctga
     8101 tcctctcgcc catgccctga gcgctcgcca cggcgcggta gcgcgtgccg ctttgttaaa
     8161 ctctcgcctt tatccggcac cgacccccgc acccatcatg tcccgcaagc tcctcgtcac
     8221 caacgccctg ccctacgcca acggcgacat ccacctcggc cacctcgtgg gctacatcca
     8281 ggccgacatc tgggtgcgct tccagcgcat gcgaggtcat tcggtgcact acgtgtgcgc
     8341 ggacgacacc cacggcacgc cggtgatgct gcgcgccgag aaggaaggcc tcacccccga
     8401 gcagctcatc gagcgcgtgc acggcgagca cctgcgcgac ttcaccgcct tcggcgtcgc
     8461 cttcgacaac taccactcca cgcacagcgt cgagaaccgc ttctacgccg aggacatcta
     8521 cggcaagctc aagtcgggcg gtctcatcga cacgcgctcg atcgagcagt actacgaccc
     8581 ggtcaaggag atgttcctgc ccgaccgctt catcaagggc gaatgcccca agtgcggtgc
     8641 ggccgaccag tacggcgaca actgcgaggc ctgcggcgcg gcctacgccc ccaccgagct
     8701 caagaacccc tactcggccg tgtccggcgc caagccggtg ctcaagacct cggagcacta
     8761 cttcttccgc ctctcggacg agcgcgcggt cgccttcctg cgcgaatgga cgcggggcac
     8821 caacgccgcc ggcgaacgcc gcctgcaggc ggaagcggcc aacaagatga aggagtggct
     8881 cggcgaggaa ggcgagaaca agctctccga ctgggacatc tcgcgcgacg cgccctactt
     8941 cggcttcgag atcccgggcg cgccgggcaa gtacttctat gtgtggctgg acgcgccgat
     9001 cggctacctc gccagcttcc gcaacctcgc cgccaagcgc gccgccgcgg gcgagcacat
     9061 cgccgtcgag gactacaccg acgccagccg cgccgccgcc gccggcaccg agatggtgca
     9121 cttcatcggc aaggacatcc tctacttcca cgccctgttc tggcccgcga tgctgaagtt
     9181 cgccggctac gccacgccca gccggctgtg cgtcaacggc ttcctgaccg tcgacggcgc
     9241 caagatgagc aagagccgcg gcaccttcat caccgcgcac tcctacatcg cccagaagct
     9301 caaccccgag tggctgcgct actacttcgc cggcaagtcc aacggcacca tggaagacgt
     9361 cgacctcaac ctcgacgaca tgatcgccaa ggtcaattcc gacctcgtcg gcaagttcgt
     9421 gaacatcgcc agccgctgtg ccggcttcat cggcaagcgc ttcgacggca ggctgggcga
     9481 ggccgatgcc gcagcctgtg ccgaattcgc caccgcctgg gccgagggcc gcgtcgccaa
     9541 cgcgtacgag gaacgcgact acggccgcgc gctgcgcgag atcatgcgcc tggccgatct
     9601 cgccaatcag tacgtgaacg accacaagcc gtgggaactg gccaagcagg aaggccagga
     9661 ggcccgcctg cacgccgtgt gcagcaccgc gctgaccatg ttccgcgacc tcacccgcta
     9721 cctcaagccg gtgctgccgg cgctcgcggc gcaggtcgag gccttcctcg ccatcccggc
     9781 gatggattgg cagggcgact gggccccgct gcccgccggc cacgccatcc aggcatacag
     9841 ccacctgatg acccgcgtcg agcgcaagca ga
//
LOCUS       DAOTIN010000119         9704 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_8339_length_9704_cov_9.501088, whole genome shotgun sequence.
ACCESSION   DAOTIN010000119 DAOTIN010000000
VERSION     DAOTIN010000119.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 9704)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 9704)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9704
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_8339_length_9704_cov_9.501088"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..240)
                     /locus_tag="P5537_13925"
     CDS             complement(<1..240)
                     /locus_tag="P5537_13925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004265627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
                     /protein_id="HRV79184.1"
                     /translation="MALSDLVVRQAKATGKAYTLPDLDGLSLAVTAAGGRTWHFRYYW
                     AGKQKRISLGTYPEVTLREARSLRDEARALIAKGIN"
     gene            complement(478..552)
                     /locus_tag="P5537_13930"
     tRNA            complement(478..552)
                     /locus_tag="P5537_13930"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(517..519),aa:Gly,seq:ccc)
     gene            complement(635..2365)
                     /gene="ptsP"
                     /locus_tag="P5537_13935"
     CDS             complement(635..2365)
                     /gene="ptsP"
                     /locus_tag="P5537_13935"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HRV79185.1"
                     /translation="MPFTLHGLAVSQGIAIGHVHLVSHALLEVNHYHVAPRYLDEELA
                     RLDEALATVQGELIGLKAVTTAGQAHSEVGAFVDLQLMMLADPMLVDAARDLVTERRC
                     NAEWALVQQMEHLVEQFRQIEDPYLRERQADVVQVVERLVKVLLGHPGHLPPRRRDGL
                     GSIVVAHDLSPADTIGFRDHNIAGFVTDVGGPTSHTAIVARSLKIPAVVGLHHVRDLL
                     EDDELIIVDGTRGVIIVAPDEEIVEEYRLRRSELEIERSKLNRLRDTRATTLDGEEVN
                     LLANIEGPKDLPAVKTANADGIGLYRTEFLFIGRDTLPDEEEQYEAYRAVVKALPGKS
                     VTIRTFDVGADKALNGAQAREEPNPALGLRAVRYSLAEPKMFKTQLRALLRASAHGRL
                     QIMVPMLAHAQEVDQCLALIEKAKAELRAEKVKFDEGIRIGGMIEVPAAALSLGMFIR
                     RLAFLSIGTNDLIQYTLAIDRSDEAVAHLYDPLHPAVLKLIAGTISSGARFGLPVSVC
                     GEMAGDPLYTELLLGMGLRNFSMHPGSILEIKQQILRADLGELAPKVQRILKMDEPAR
                     IREAVERLTT"
     gene            complement(2367..2636)
                     /locus_tag="P5537_13940"
     CDS             complement(2367..2636)
                     /locus_tag="P5537_13940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HRV79186.1"
                     /translation="MPRGDAPIINKLGLHARASAKLTQLASSFPCEVWLERNGRRVNA
                     KSIMGVMMLAAARGSTITIDTQGEGADEALQAIQELVADRFGEGE"
     gene            complement(2689..3078)
                     /locus_tag="P5537_13945"
     CDS             complement(2689..3078)
                     /locus_tag="P5537_13945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004265631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HRV79187.1"
                     /translation="MIGLFLVTHGTLGEALIQCVCHVLDKRPPLLGQLGLSAAEDPAD
                     ALPLARRMIATVDEGDGVLLLADLYGATPCNVATRLIEPGRIELVAGVNLPMLLRLLT
                     HREGDLDTLIRRALSGAGDGVIHVQPG"
     gene            3297..4928
                     /locus_tag="P5537_13950"
     CDS             3297..4928
                     /locus_tag="P5537_13950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0071705 - nitrogen compound transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BCCT family transporter"
                     /protein_id="HRV79188.1"
                     /translation="MTDGSDPMAPSGAVNPIDTDYKVGQDNIVLNVGPFGLDIHNRVF
                     AVSGLLVVAFVVLTLAFQNQVEPMFSAMRNWLTSNLDWFFIAAGNIFVVVMLAVAVSP
                     LGKVRLGGTEATPDYTYLGWFSMLFAAGMGIGLMFFGVSEPLSHFGSAFGGTTVEGGV
                     RTDWAPLGAAAGDAEAATRLGMAATIYHWALHPWAIYATIALGLALFSFNKGLPLTIR
                     SVFYPLLGERIWGWPGHIIDILAVLATLFGLATSLGYGASQASSGLNFLFDVPLGNTT
                     QIVLVIGITAIALASVVAGLDAGVKRLSEINMALALLLMVFVIAVGPTLDILSGFFAN
                     LGAYVQYLPALSNPVGREDINYSQGWTAFYWAWWISWSPFVGMFIARVSRGRSVREFI
                     LAVLIVPSLACVLWMTVFGETAILQVVRDGYEAAKTAELPLQLFTMLDALPLASITSF
                     IAIILVVVFFVTSSDSGSLVIDVIAAGGKVDAPLPQRVFWCTFEGLVAIALILGGGLV
                     ALQAMAVSTGLPFTIVLLMSAVAVVKGLASEPRPR"
     gene            4952..6829
                     /locus_tag="P5537_13955"
     CDS             4952..6829
                     /locus_tag="P5537_13955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008773 - [protein-PII]
                     uridylyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF294 nucleotidyltransferase-like
                     domain-containing protein"
                     /protein_id="HRV79189.1"
                     /translation="MQVEQLEILDFLRAHPPFDALPEEVLQRVAAAVDVRYYKAGETI
                     VEFGQVAEFWHVVRSGAVEVFRRNGTLYNRLTAGGYFGEFGLLRNGRVRFPVSALEDT
                     LLYLIPRELFAELFDQHESFADLVEVEDRTRLRQVMSKREDANDLLSATVETLVGRAA
                     VTLPSTASARELAQRMTEEGVSSLLILDDNPEVPELPVLSGIVTDRDLRTRLVAPGLS
                     YDTPAAEIMSRGVVSVSHNQLVFEAMLAMLRHNVHHLPVLRNQRPLGVIALSDIIRYE
                     SRNSLFVVGSIFRQQSVDELAALVPEVRACFARMVGEDASSHMIGSAMAAIGRSFKQR
                     LLELAEAELGPPPVPYCFLALGSMARQEQLIVTDQDNALILDNRFDPAHHDDYFKALA
                     AFVSDGLARCGYSYCTGGVMATNVQWRQPLKVWERYFTEWIERPTPESLLNAGIFFDL
                     DGVWGRTEWATRLRELIARKARGNSRFLACMARNALLRTPPLGFFKDFVVESDGRHTG
                     AINIKRRGTAPLADLVRVHALAIGSMALNSFERLKDIIDAAILPLGRGQDLFDALEFI
                     CMVRARHQAESLAAGEEPDNSIVPEKLSEFERKSLRDAFLILGNAQKFLKYRYQPGRA
                     N"
     gene            6840..7613
                     /locus_tag="P5537_13960"
     CDS             6840..7613
                     /locus_tag="P5537_13960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HRV79190.1"
                     /translation="MLHLGDLKKAGAAAPSASRGRDAQGVADWPARFAGLAATARDAR
                     LQAFYAAGAVAGETALKDVPMVAIDVETTGLDPARDEIVSIGLVPMDAACIRSSASRY
                     WVVRPHAELRPESVTIHAITHAQIEAAPDFGAIVGELLAALAGRVVVVHCREIERRFL
                     DVALKARLGEGIEFPVIDTMELEARLHRRPPPGLLARLFGRKPAPVSIRLADSRERYN
                     LPRYRAHHALTDALATAELLQAQVAQRFAPETPLRELWC"
     gene            complement(7711..8163)
                     /locus_tag="P5537_13965"
     CDS             complement(7711..8163)
                     /locus_tag="P5537_13965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004265633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79191.1"
                     /translation="MMASENPELALRVETDRFGPFLFQVGVDAVRLQLPMQRVEDAHR
                     RFVASPLAQVANPLEREVIASSIYGTNTIEGGTLTEDETRSALNLDPAQGLDAVRHAP
                     WYASLYLKLNDKTRSRDLKKLRGLELVVLDTDNRLWPGCIRPKNVKAP"
     gene            complement(8374..>9704)
                     /locus_tag="P5537_13970"
     CDS             complement(8374..>9704)
                     /locus_tag="P5537_13970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HRV79192.1"
                     /translation="DAIYANPDATEDDYMHAAELEGKVGEYDGYTAEARAGELLLGVG
                     IPTELHNGPMSEVAPGWKLRVLLTQALFANPDILLLDEPTNNLDINTIRWLEDVLNNR
                     DCTMVIISHDRHFLNQVCTHMADLDYGTITIYPGNYDDYMEASTMARERQSSANARAK
                     DKIQELQAFVRRFSANKSKAKQATSRLKLIDKLKPEDVKPSSRQYPWIRFDYDDKDKL
                     HRLACEVDNVSFAYEGMDKPLIHRFSIAIEAGEKVAIIGENGVGKTTLLKLLVGELQP
                     QKGAIKWAEKAKPGYYAQDHSSDFAEDVSLTDWIAPYSRITAAATGEDNETLLRGTLG
                     RLLFSGDEVRKSVKVISGGEQGRMLFGKLMLSRPNVLLMDEPTNHLDMESIESLNTGL
                     DKFNGTLVFVSHDREFVSSLATRIIEIKLDHQIVDYRGTYEEYLQSQGLD"
BASE COUNT         1398 a         3209 c         3395 g         1702 t
ORIGIN      
        1 attgatgccc ttggcgatca gggcgcgcgc ttcgtcgcgc aggctgcgcg cctcgcgaag
       61 cgtcacctcc gggtaggttc cgagcgagat ccgcttctgc ttgcccgccc agtagtagcg
      121 gaagtgccaa gtcctgcccc ccgcagccgt cacggctagt gagaggccat ccaagtcagg
      181 gagggtgtag gccttgccgg ttgccttggc ctgtcgaacg accaggtctg agagtgccat
      241 gctcttgctc ctgaacatga gtcaggaacc agatgctggt cacatcgacc tcgcccctcg
      301 atcaacaatc cggaaaccgc cgtgccctca aaaatggact tgtttgtgga cttaaaagtc
      361 ccggctgtcg gcggatcgcg gtggaacaca gcagaacgtc aaggagagaa aagtcgttgt
      421 gcgccaagga cttgcagatt atcctggact tctgcggaag tccgcagatt gatgcagtgg
      481 agcgggtgaa gggaatcgaa ccctcgtcat gagcttggga agctcaggta atagccatta
      541 tacgacaccc gcatctgggg ccgagctggc gtcggccgcg aagaaggccg gattgtactg
      601 ccacggccga tgcgcttcaa ccgcggcggt gttttcaggt cgtgagccgc tccaccgcct
      661 cgcggatgcg cgccggctcg tccatcttga ggatgcgctg caccttgggg gcgagctcgc
      721 cgaggtcggc gcgcaggatc tgctgcttga tctcgaggat gctgcccggg tgcatggaga
      781 agttgcgcag gcccatgccg agcagcaact cggtgtacag cgggtcgccc gccatctcgc
      841 cgcaaaccga caccggcagg ccgaagcgcg cgccgctgga gatggtgccg gcgatgagct
      901 tgagcaccgc ggggtggagc gggtcgtaga ggtgcgcgac ggcctcgtcc gagcggtcga
      961 tcgccagcgt gtactggatg aggtcgttgg tgccgatgga caggaaggcc agccggcgga
     1021 tgaacatgcc gagcgagagc gcggcagcgg gaacctcgat catgccgccg atgcggatgc
     1081 cctcgtcgaa tttgaccttc tcggcgcgca gctcggcctt ggccttctcg atcagggcga
     1141 ggcactggtc gacctcctgc gcgtgggcga gcatggggac catgatctgc aggcggccgt
     1201 gcgccgaggc gcgcagcagc gcgcgcagct gggtcttgaa catcttgggc tcggccagcg
     1261 agtagcgcac cgcgcgcagg ccgagcgcgg ggttgggctc ctcgcgcgct tgcgcgccgt
     1321 tgagcgcctt gtcggcgccg acgtcgaagg tgcggatggt gaccgacttg ccgggcaggg
     1381 ccttgaccac cgcgcggtag gcttcgtact gctcttcctc gtcgggcagc gtgtcgcggc
     1441 cgatgaagag gaactcggtg cggtagagcc cgatgccgtc ggcgttggcg gtcttgaccg
     1501 cgggcaggtc cttgggcccc tcgatgttgg cgagcaggtt gacctcctcg ccgtcgagcg
     1561 tggtggcgcg ggtgtcgcgc aggcggttga gcttggagcg ctcgatctcg agctcgctgc
     1621 ggcgcaggcg gtattcctcg acgatctcct cgtcgggggc gacgatgatc acgccgcggg
     1681 tgccgtcgac gatgatgagc tcgtcgtcct cgagcaggtc gcgcacatgg tgcaggccga
     1741 caaccgcggg gatcttgagg ctgcgcgcga cgatcgcggt gtggctggtg ggcccgccga
     1801 cgtcggtgac gaagccggcg atgttgtggt cgcggaagcc gatggtgtcg gcgggcgaga
     1861 ggtcgtgggc gacgacgatg ctgcccagcc cgtcgcgccg gcgcggcggc aggtggccgg
     1921 ggtggccgag cagcaccttg accaggcgct cgacgacctg gaccacgtcg gcctggcgtt
     1981 cgcgcaggta ggggtcctcg atctggcgga actgctcgac caggtgctcc atctgctgca
     2041 ccagcgccca ctcggcgttg cagcggcgct cggtgacgag gtcgcgggcg gcgtcgacca
     2101 gcatcgggtc ggcgagcatc atcagctgca ggtcgacgaa ggcgccgacc tcgctgtgcg
     2161 cctgaccggc ggtggtgacc gccttgaggc cgatcagttc gccctggacg gtggcgagcg
     2221 cctcgtcgag gcgggcgagc tcctcatcga ggtagcgcgg cgcgacgtgg tagtggttga
     2281 cctcgagcag cgcgtgcgag acgaggtgga cgtggccgat cgcgatgccc tgcgagaccg
     2341 ccaggccgtg cagcgtgaat ggcatctcat tccccttcgc cgaagcggtc ggcgaccagc
     2401 tcctggatgg cctgcagcgc ctcgtcggcg ccctcgccct gggtgtcgat cgtgatcgtg
     2461 ctgccgcgcg cggccgccag catcatcacc cccatgatgc tcttggcgtt gacccggcgg
     2521 ccgttgcgct cgagccagac ctcgcacgga aagctgctgg cgagctgggt gagcttggcc
     2581 gaggcgcgtg cgtgcaggcc gagcttgttg atgatggggg cgtctcctcg cggcatcgtc
     2641 gcggttctcc gtggtgcgtt cgttcgtgtc gttgtatggc ggcggagatc agcccggctg
     2701 cacgtgtatc acgccgtcgc ccgcgccgct gagcgcgcgc cggatcaggg tgtcgaggtc
     2761 gccctcgcgg tgggtgagca ggcgcagcag catcggcagg ttgacgccgg cgacgagctc
     2821 gatgcgaccc ggctcgatga gccgggtcgc gacgttgcaa ggggtggcgc cgtagaggtc
     2881 ggcgagcagc agcacgccgt cgccttcgtc caccgtggcg atcatccggc gtgcgagggg
     2941 cagggcgtcg gcggggtcct ctgccgccga caggccgagc tggccgagca gcggcgggcg
     3001 cttgtcgagg acgtggcaga cgcactggat cagcgcttcg ccgagggtgc cgtgggtgac
     3061 gagaaagagg ccgatcatgg ggttctccgc agcctccgat tctagccgag tcgccgcctg
     3121 ccgtgccgct gcgggcgggt ggggcgagcg gacgaggcgg gtggcaatcc catccgctgt
     3181 tttacatttg tacaaaatat atgtcgaaaa atgatagact tcaccctctc ttcgccgcgg
     3241 tgaagcaagg ccgtgcgcgt gaattccatg aatttcccta atgacaagga gctgcaatga
     3301 cggatggcag cgatccgatg gccccctcgg gggcggtcaa tccgatcgac accgactaca
     3361 aggtcggcca ggacaacatc gtcctcaacg tcgggccctt cggcctcgac atccacaacc
     3421 gcgtgttcgc cgtgtccggc ctgctggtgg tcgccttcgt ggtgctcacc ctggccttcc
     3481 agaaccaggt cgagccgatg ttcagcgcga tgcgcaactg gctgacctcg aacctggact
     3541 ggttcttcat cgccgccggc aacatcttcg tggtggtcat gctcgccgtg gcggtgtcgc
     3601 cgctcggcaa ggtgcgcctg ggcggcaccg aggccacgcc cgactacacc tacctgggct
     3661 ggttctcgat gctgttcgcc gccggcatgg gcatcgggct gatgttcttc ggcgtgtccg
     3721 agccgctctc gcacttcggc agcgccttcg gcggcaccac ggtcgagggc ggcgtgcgca
     3781 ccgactgggc gccgctgggt gcggccgccg gcgacgccga agccgcgacc cggctcggca
     3841 tggcggccac gatctaccac tgggcgctgc atccgtgggc gatctacgcc accatcgcgc
     3901 tcgggctggc gctgttctcc ttcaacaagg gcctgccgct gaccatccgc tcggtgttct
     3961 acccgctgct cggcgagcgc atctggggct ggccgggcca catcatcgac atcctcgccg
     4021 tgctcgcgac cctgttcggc ctggcgacct cgctcggcta cggcgcctcg caggcgagct
     4081 ccggcctcaa cttcctcttc gacgtgccgc tcggcaacac cacccagatc gtgctggtga
     4141 tcggcatcac cgcgatcgcg ctggcctcgg tggtggcggg cctggacgcg ggcgtcaagc
     4201 gcctgtccga gatcaacatg gcgctggcgc tgctgctgat ggtcttcgtg atcgcggtcg
     4261 ggccgacgct ggacatcctc tccggcttct tcgccaacct cggcgcctac gtgcagtacc
     4321 tgccggcgct gtccaacccg gtcgggcgcg aggacatcaa ctactcgcag ggctggaccg
     4381 ccttctactg ggcgtggtgg atctcgtggt cgcccttcgt cggcatgttc atcgcgcgcg
     4441 tctcgcgcgg gcgcagcgtg cgcgagttca tcctcgcggt gctgatcgtg ccctcgctcg
     4501 cctgcgtgct gtggatgacg gtgttcggcg agaccgcgat cctgcaggtg gtgcgcgacg
     4561 gctatgaggc ggcgaagacg gccgagctgc cgctgcagct cttcaccatg ctcgacgcgc
     4621 tgccgctggc ctcgatcacc tccttcatcg cgatcatcct ggtggtggtg ttcttcgtga
     4681 cctcgtccga ctcgggctcg ctggtgatcg acgtgatcgc cgccggcggc aaggtcgacg
     4741 cgcccttgcc gcagcgcgtg ttctggtgca ccttcgaggg cctggtcgcg atcgcgctga
     4801 tcctcggtgg cggcctggtg gcgttgcagg cgatggcggt gtccaccggc ctgcccttca
     4861 ccatcgtgct gctgatgtcg gcggtggccg tggtcaaggg cctggcctcg gagccgcgtc
     4921 cgcgctgacc gccacgcctg gacccgaacc catgcaggtc gaacagctcg agatcctcga
     4981 tttcctccgc gcccacccgc ccttcgacgc gctgcccgaa gaggttctgc agcgcgtcgc
     5041 ggcggcggtc gacgtgcgtt actacaaggc gggcgagacc atcgtcgagt tcggccaggt
     5101 ggccgagttc tggcatgtgg tgcgcagcgg cgcggtcgag gtcttccggc gcaacggcac
     5161 gctctacaac cgcctgactg ccggcggcta cttcggcgag ttcggcctgc tgcgcaacgg
     5221 ccgtgtgcgc ttcccggtga gcgcgctgga agacacgctg ctctacctga ttccgcgcga
     5281 gctcttcgcc gaactcttcg accagcacga gagcttcgcc gacctggtcg aggtcgagga
     5341 ccgcacccgc ctgcgccagg tgatgtccaa gcgcgaggac gccaacgacc tgctctctgc
     5401 caccgtcgag accctggtcg ggcgcgctgc ggtgaccctg cccagcaccg cgagcgcgcg
     5461 cgagctggcg cagcgcatga cggaagaggg cgtgtcctcg ctgctgattc tcgacgacaa
     5521 ccccgaagtg cccgaactcc ccgtgctttc cggcatcgtc accgaccgcg acctgcgcac
     5581 gcgactggtc gcgcccggcc tgtcctacga cacgccggcg gccgagatca tgtcgcgcgg
     5641 cgtggtgtcg gtgagccaca accagctcgt cttcgaggcc atgctggcga tgctgcgcca
     5701 caacgtgcac cacctgccgg tgctcaggaa ccagcgcccg ctcggcgtga tcgcgctctc
     5761 ggacatcatc cgctacgagt cgcgcaacag cctgttcgtg gtcggcagca tcttccgcca
     5821 gcagtcggtg gacgagctcg ccgcgctggt tcccgaggtg cgcgcctgct ttgcgcgcat
     5881 ggtgggcgag gacgccagct cgcacatgat cggcagcgcc atggcggcga tcgggcgcag
     5941 cttcaagcag cgcctgctcg agctcgccga ggccgagctc ggcccgccgc cggtgcccta
     6001 ctgcttcctc gcgctcggct cgatggcgcg ccaggagcag ctcatcgtca ccgaccagga
     6061 caacgcgctg atcctggaca accgcttcga ccccgcgcac cacgacgact acttcaaggc
     6121 gctcgccgcc ttcgtcagcg acggcctggc gcgctgcggc tatagctact gcaccggcgg
     6181 cgtgatggcg accaacgtgc agtggcgcca gcccctgaag gtgtgggagc gctacttcac
     6241 cgaatggatc gagcgcccga cccccgagtc cctgctcaac gccggcatct tcttcgacct
     6301 cgacggggtg tggggccgca ccgagtgggc gacccggctg cgcgagctga tcgcgcgcaa
     6361 ggcccgcggc aactcgcgct ttctcgcctg catggcgcgc aacgcgctgc tgcgcacgcc
     6421 gccactcggt ttcttcaagg acttcgtggt cgagtccgac ggccgccaca ccggcgcgat
     6481 caacatcaag cgccgcggca ccgcgccgct cgccgacctg gtgcgggtgc acgcgctggc
     6541 gatcggctcg atggcgctga actccttcga gcgcctgaag gacatcatcg acgccgcgat
     6601 cctgccgctc gggcgcgggc aggacctctt cgacgccctc gaattcatct gcatggtgcg
     6661 cgcccgccac caggccgagt cgctcgccgc cggcgaggag ccggacaaca gcatcgtccc
     6721 cgagaagctg tcggagttcg agcgcaagag cctgcgcgac gccttcctga tcctcggcaa
     6781 cgcgcagaaa ttcctcaagt accgttacca gcccgggcgg gcgaactgag ggcgcggccg
     6841 tgctgcacct cggcgacctg aagaaggctg gcgcagctgc gccatcagcc agccgcgggc
     6901 gcgacgcaca gggggtggcg gactggccgg cgcgcttcgc cgggctcgcc gccaccgcgc
     6961 gcgacgcgcg cctgcaggcc ttttatgccg cgggtgcggt ggccggcgaa accgcgctga
     7021 aggacgtgcc aatggtggcg atcgacgtcg agaccaccgg actggatccg gcgcgcgacg
     7081 agatcgtcag catcgggctg gtgccgatgg atgccgcctg catccgctcc agcgcctcgc
     7141 gctactgggt ggtgcgcccg cacgccgagc tgcgccccga atcggtgacg atccacgcca
     7201 tcacccacgc gcagatcgaa gccgcgcccg acttcggcgc catcgtcggc gagctgctgg
     7261 cggcgctcgc cgggcgcgtg gtggtggtgc attgccgcga gatcgagcgc cgctttctcg
     7321 atgtggcgct gaaggcgcgc ctgggcgagg gcatcgagtt cccggtgatc gacaccatgg
     7381 agctggaggc ccgtctgcac cgccgcccgc cgccggggct cctggcgcgc ctgttcggcc
     7441 gcaagcccgc gccggtgtcg atccgcctcg ccgacagccg cgagcgctac aacctgccgc
     7501 gctaccgcgc ccaccacgcg ctcaccgacg cactcgccac cgccgagctg ctgcaggcgc
     7561 aggtggcgca gcggttcgcg ccggagacgc cgctgcgcga gctgtggtgc tgaaccgcct
     7621 gccctgcgtc caccctggac ccgggcgccc ctccatcgtg cggaattgcg ctcgactcgc
     7681 caggaccgcc gcgaacttgc agatgcggga tcagggcgcc ttgacgttct tcggacggat
     7741 gcagcccggc cacaggcggt tgtccgtgtc gaggacgacg agttcgagcc cgcgcagctt
     7801 cttgaggtcg cggctgcggg tcttgtcgtt gagcttgagg tagaggctgg cgtaccaggg
     7861 ggcgtgacgc accgcgtcca gcccctgcgc ggggtcgagg ttgagggcgg agcgtgtttc
     7921 atcctcggtg agcgtgccgc cttcgatcgt gttggtcccg tagatgctgc tggcgatcac
     7981 ttcgcgctcg agcggattcg ccacctgcgc gagcggcgag gcgacgaagc gccgatgggc
     8041 atcctcgacg cgctgcatcg gaagctgcag gcggacagcg tcgacgccca cctgaaagag
     8101 gaaggggccg aagcggtcgg tttcgacgcg cagcgcgagc tcgggattct cggaggccat
     8161 catgtctgcc ggaatgtccg ctcaaaaaaa acagggttct agtttgtttt caatgagatg
     8221 aagcgcgtaa ccggcgatcc atgtccgtcc ggatgtccag cgctcgaggc atgatggacc
     8281 cggctcggta aaagcgaagg ggcgaaccgg ccgccgcatc gagcggcagc gggttcgccc
     8341 cgttgcgtgc atgcgcggcc gcagccgccg ggatcagtcc agcccttgcg actgcaggta
     8401 ttcctcgtag gtgccgcggt aatccacgat ctggtgatcg agcttgatct cgatgatgcg
     8461 cgtggccagc gagctcacga actcgcggtc gtgcgagacg aacaccagcg tgccgttgaa
     8521 cttgtccagg ccggtgttga gcgactcgat cgattccatg tcgaggtggt tggtcggctc
     8581 gtccatcagc agcacgttgg ggcgcgacag catgagcttg ccgaacagca tgcggccctg
     8641 ctcgccgccg gagatcacct tcaccgactt cctcacctcg tcgcccgaga acagcaggcg
     8701 gccgagcgtg ccgcgcagca gggtctcgtt gtcctcgccg gtggcggcgg cggtgatgcg
     8761 ggagtagggc gcgatccagt cggtgaggct gacgtcctcg gcgaagtcgc tcgagtggtc
     8821 ctgcgcgtag tagcccggct tggccttctc cgcccacttg atggcgccct tctgcggctg
     8881 cagctcaccc accagcagct tgagcagcgt ggtcttgccg acgccgttct cgccgatgat
     8941 ggcgaccttc tcgccggcct cgatggcgat cgagaagcgg tggatcagcg gcttgtccat
     9001 gccctcgtag gcgaaggaga cgttgtccac ctcgcaggcg aggcggtgca gcttgtcctt
     9061 gtcgtcgtag tcgaagcgga tccacgggta ctggcgggaa gacggcttca catcctcggg
     9121 cttgagcttg tcgatcagct tgaggcggct ggtggcctgc ttggccttgg acttgttggc
     9181 cgagaagcgg cgcacgaagg cctgcagctc ctggatcttg tccttggcgc gggcgttggc
     9241 cgacgactgg cgctcgcgcg ccatcgtcga cgcttccatg tagtcgtcgt agttgcccgg
     9301 gtagatcgtg atcgtgccgt agtccaggtc ggccatgtgg gtgcacacct ggttcaggaa
     9361 gtggcggtcg tgcgagatga tgaccatcgt gcagtcgcgg ttgttgagca cgtcctcgag
     9421 ccagcggatg gtgttgatgt cgaggttgtt ggtcggctcg tcgagcagca ggatgtcggg
     9481 gttggcgaac agcgcctggg tgagcagcac gcgcagcttc cagcccgggg cgacctcgct
     9541 catcgggccg ttgtgcagtt cggtggggat gcccacgccg agcagcagct cgccggcgcg
     9601 cgcctcggcg gtgtagccgt cgtactcgcc gaccttgccc tcgagctcgg cggcgtgcat
     9661 gtagtcgtcc tcggtggcgt ccgggttggc gtagatcgcg tcgc
//
LOCUS       DAOTIN010000120         9680 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_8369_length_9680_cov_9.514597, whole genome shotgun sequence.
ACCESSION   DAOTIN010000120 DAOTIN010000000
VERSION     DAOTIN010000120.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 9680)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 9680)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9680
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_8369_length_9680_cov_9.514597"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..310)
                     /locus_tag="P5537_13975"
     CDS             complement(<1..310)
                     /locus_tag="P5537_13975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosolic protein"
                     /protein_id="HRV79193.1"
                     /translation="MPARAAQDDYDSPWKEAVEHAFPEFMEFYFPDASRQIDWARGHR
                     FLDKELQQIVRDAALGRRHVDKLASVTTHTGEEDWLCVHIEVQGSMDPGFARRMFVYN
                     Y"
     gene            529..1131
                     /locus_tag="P5537_13980"
     CDS             529..1131
                     /locus_tag="P5537_13980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HRV79194.1"
                     /translation="MPLTLAAPVHSELIIKKSRFIGCVQPMSDRAGAQKVVAALWAQH
                     PGARHVCWALLAGGQSAAVDDGEPSGTAGRPMLDVLRHQDLEGVLATVVRYFGGVKLG
                     AGGLVRAYTDAVAQALLQAEKVPIVRLATLRCVVPYAMEGLLRRELDAAGASLLAVVH
                     GQAVELCFSLPEEAAVALRARLGEAGQGRIEWLPVPDEVA"
     gene            complement(1247..2026)
                     /locus_tag="P5537_13985"
     CDS             complement(1247..2026)
                     /locus_tag="P5537_13985"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_function: GO:0017168 - 5-oxoprolinase (ATP-hydrolyzing)
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpA"
                     /protein_id="HRV79195.1"
                     /translation="MNKTINLNADLGESFGAWTMGEDEALLQVVRSANIACGFHAGDP
                     VVMRHTVRTALAAGVSLGAHPAYPDLQGFGRRPMKMAPAELEAMIIYQVGALAGMAAA
                     EGGRVTHVKPHGALNNQACEDAALADAVARAVRAIDPDLILLAPVLSELHAAGERAGL
                     KVAGEIFADRAYTDKGTLVARGQPGAVIHDHDELVTHVLRMLDAGGVVSQSGKHLPAA
                     MDSICVHGDTLGAVESARHLRSELEARGWTVVALPEVVAGR"
     gene            complement(2055..3110)
                     /locus_tag="P5537_13990"
     CDS             complement(2055..3110)
                     /locus_tag="P5537_13990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase family
                     protein"
                     /protein_id="HRV79196.1"
                     /translation="MSTQTELEIVTPGAFASIQDEGRRGFRRIGVPWAGVLDRRLMRL
                     ANALAGRPEDAPVIECFDGGLHVVAHGGAVKLAVAGDAVVEVDGPEGRRQLAPWRSVT
                     IAAGEALRIRKMGSGRIAMVAVAGLEVAPVMGSASTYVRAGLGGADGSGRALAAGMRL
                     ALAEADAWGSDRVLTQPPEPDPRPIRLVPGPQADHFSAAALEALVGGDYRVTAEADRM
                     GVRLEGAKLEHSGAADIVSDATVPGSIQVPGAGQPIVLLADAQTAGGYPKIATVIGAD
                     LGRLAALRPGQTLRFATVTAAEGAQLARAEEAETRALITAIRPLPADGIDLLALYTGN
                     LVDGVVHALDTEFRPLY"
     gene            complement(3107..3868)
                     /gene="pxpB"
                     /locus_tag="P5537_13995"
     CDS             complement(3107..3868)
                     /gene="pxpB"
                     /locus_tag="P5537_13995"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HRV79197.1"
                     /translation="MSVRILDAGDAALTIEFGSVIDPALLAAVNALDAAILRLQSAGD
                     LPGVIETMPTFRSLTVFFDPLATDRDTVLGVLQPLIAAAEHGSPADGRHWRLPVCYEG
                     EAAPDLAEVAGTIGIGEDEVVALHSGTEYLVYMLGFLPGFPFMGDLPERLRLPRRAQP
                     RVRVPAGSVAIATGLTAIYPWESPGGWHLLGRCPVPLFDARRASPSLLAAGDRVRFVP
                     VSTAECRAIEAAACTADFDPMQWLDSAPTPAENAA"
     gene            complement(3885..4400)
                     /locus_tag="P5537_14000"
     CDS             complement(3885..4400)
                     /locus_tag="P5537_14000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix DNA-binding protein"
                     /protein_id="HRV79198.1"
                     /translation="MGDSGPIVSSQHLVSAKSPQVSEFEFGLIIAWHAFARWMMRCMT
                     AAGVKDMTPIDVLVLHHVAHRDTEKRLADIGFVLNVEDTHVVSYSLRKLAGLGLVQSA
                     KRGKEAFWSVTDKGREICLVYRDVREACLMPGFSGSAEENRRIAELAQLLRTVSGRYD
                     QAARAASTSPL"
     gene            4576..5565
                     /locus_tag="P5537_14005"
     CDS             4576..5565
                     /locus_tag="P5537_14005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HRV79199.1"
                     /translation="MTFSHPLLKAITGSLLGLGFVAAAHAQTAWDMPTPYPASNFHTE
                     NIQQFAKEVDAATGGKLKITVHANGSLFKANEIKRAVQAGQAQIGELIISGLANEDAL
                     YALDTVPFLATSYADSKKLWEASKQAVEARLAKNGLKVLYSVAWPPQGLYSKTELKTI
                     GDLKGMKIRSYSPTVARMIELMGGQPVTVQAADLTQALSTGVVSANLTSSATGYDTKS
                     WEQLSHYYDIQAWLPKNIVFVSKKAFDALDQPARDALLKAAAAAEERGWKVSEEKTAW
                     YVEQLKANKMQVQPAPEALQAELLKVGEKMTAEWVEKAGPDGQAILDAYRKLK"
     gene            5622..6140
                     /locus_tag="P5537_14010"
     CDS             5622..6140
                     /locus_tag="P5537_14010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015740 - C4-dicarboxylate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HRV79200.1"
                     /translation="MRAFLDSLYRLSGALAAIGMVATLVLVTSGVVTRPLGIYLPGTD
                     DYAGYAMAACGFFALAYTFKHGEHIRVSLLLERVGPRMRAALEWFSLAAGTAVAATLA
                     FYAVRMVLQSHEFEEISQGVDATPLWIPQLSMAIGSVVLLIALLDDLVMTMLGRAPAR
                     LATHSGEAARME"
     gene            6153..7451
                     /locus_tag="P5537_14015"
     CDS             6153..7451
                     /locus_tag="P5537_14015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0015556 - C4-dicarboxylate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015740 - C4-dicarboxylate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HRV79201.1"
                     /translation="MEVMIAAVMIGLMLALLAGGVWIGLALMAIGILGMLGFTPRAPG
                     DGMAVAIWSHGSSWTLTALPLFLWMGEILFRTKLSEDMFKGLSPWLERLPGRLLHTNI
                     IGCTLFAAVSGSSAATCATIGKIALPELERRGYPESMALGTLAGAGTLGLLIPPSIIM
                     IVYGVAADVSISKLFIGGVLPGILLATLFMGWVVVWSLMNPGKIPAPDLKTTFVEKLA
                     ASKNLIPVILLIGGVLGSIYSGIATATEAAAIGVIGSLIIAASQRTLNRKSFFGALMG
                     ATRLYCMIALILAGSAFLTLAMGYIGLPRHLAEWIGALGLSPAMLLVALAIFYILLGC
                     FLDGISIVVLTMAVLMPTIQSAGIDPLWFGIFVVVVVEMAQVTPPVGFNLFVLQGLTG
                     RDMTVIARYALPYFLLMVVAVVLLYTFPGLVTWLPGHMVG"
     gene            complement(7474..8436)
                     /locus_tag="P5537_14020"
     CDS             complement(7474..8436)
                     /locus_tag="P5537_14020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HRV79202.1"
                     /translation="MSTSAPSQIHTRLRVFLAVAHHLSFTRAGEELSITTGAVSQQIK
                     LLEDWLGQRLFRRLPRRLELTDAGKRLLTAVDPAYAAVDLAIGRLRGGALSGVVRVRT
                     LPSFLATWLVPRLPRLMARFPQIELQVEAEDSTYSLRDGEFDLAIDLNDGTYPGFQST
                     VLLEEEIFPVCSPRLLEGRPPLLGAEDLRHYPLLHDMTAWRGSPPYAEWERYLKAIGA
                     PQVEVRRGYMFNRNHITMQCAIAGMGVAIARRTLITDELDSGRLVAPFAQSVRTGKRY
                     CVIHSAGALADPRVATVRDWLVAEARAAELAAGPSADATPAPGE"
     gene            8579..>9680
                     /locus_tag="P5537_14025"
     CDS             8579..>9680
                     /locus_tag="P5537_14025"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009063 - amino acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HRV79203.1"
                     /translation="MSISVLDLFKIGVGPSSSHTVGPMRAAHDFVVELQRRGLLDQVR
                     RIEARLYGSLSATGVGHGTDRAVVAGLMGARPDEVDPDFLVGAVDAVRIDGELPLAGT
                     TTVPFDWARDLRLLPVSLPYHPNAMRIAAHGEAGVLYENTYYSVGGGFVVDEAQAQSG
                     AAAEAEVAVPYPFDTGAELLAQCRRHGLRISELMLANESAWRSEAETRTALLRIWEVM
                     RACVTRGVGHEGVLPGGLNVRRRAPALYRKLSEQASGRNMISDSMTALDWVNLYALAV
                     NEENAGGGRVVTAPTNGAAGIIPAVMHYYMKFMPGSDERDVENFLLAAAAVGALCKKN
                     ASISGAEVGCQGEVGSACAMAAAGLAEVLGGTP"
BASE COUNT         1414 a         3262 c         3484 g         1520 t
ORIGIN      
        1 ggtagttata gacgaacatg cggcgcgcga agccggggtc catgctgccc tggacctcga
       61 tgtgcacgca cagccagtct tcctcgccgg tgtgggtggt gacgctggcg agcttgtcca
      121 cgtggcgtcg gccgagcgcg gcatcgcgga cgatctgctg caactccttg tcgaggaaac
      181 ggtggccgcg cgcccagtcg atctggcggc tggcgtcggg gaagtagaac tccatgaact
      241 ccgggaaggc gtgctcgacg gcctccttcc atggactgtc gtaatcgtct tgcgctgcgc
      301 gggcgggcat tccggactcc tgggcgaggg atccggaatg ctatttggaa atatgacgaa
      361 agggaaattg gatgatcgtc ctggtggtgc cgaatcgatt cgaaagcgga tgccgtgggc
      421 gatcggagcc gtcgtcaatg cgcaggaacc aggcagcggg gttcatcccc gatcttcccg
      481 acaggccgcc gccgtgccgc cgcgcgaatc ggactagaat cccgccccat gccgctgacc
      541 ctcgccgctc ccgttcatag tgaactgatc atcaagaaga gccgcttcat cggctgcgtg
      601 cagccgatga gcgaccgcgc cggcgcgcag aaggtcgtgg ccgcgctgtg ggcgcagcat
      661 ccgggcgcgc gccacgtgtg ctgggcgctg ctcgcgggcg gacagtcggc ggcggtggac
      721 gacggcgagc cgagcggcac cgccgggcgg ccgatgctgg acgtactgcg ccatcaggac
      781 ctggagggcg tgctggcgac cgtggtgcgc tacttcggcg gcgtgaagct gggggccggc
      841 ggcttggtgc gcgcctacac ggacgccgtg gcacaggcct tgctgcaggc ggagaaggtg
      901 ccgatcgtgc gtctggcgac gctgcgctgc gttgtgccct atgcgatgga gggactgctg
      961 cggcgcgagc tcgacgccgc gggggcgagc ctgctggcgg tggtgcacgg gcaggcggtg
     1021 gagctgtgct tcagcctgcc cgaggaggcc gccgtcgcct tgcgcgcgcg cctcggcgag
     1081 gcggggcagg ggcggatcga gtggctgccc gtgccggacg aggtggcctg aaagggcttc
     1141 aggccggtga tcgcctgtct cggtggtgag agcgggcttg ctcgcgaacg ggtgcgggaa
     1201 gcttcgcggg aaggcctttc gccaagggct cccagtcgag acccgctcaa cgccccgcga
     1261 ccacctccgg cagtgccacg accgtccacc cgcgcgcttc gagctcgctg cgcaggtggc
     1321 gggcgctttc caccgcgccc agggtgtcgc cgtgcacgca gatgctgtcc attgccgcgg
     1381 gcaggtgctt gccgctctgg ctgaccacgc cgccggcgtc gagcatgcgc agcacgtggg
     1441 tgacgagttc gtcgtggtcg tggatgaccg cgccgggctg gccgcgcgcc accagcgtgc
     1501 ctttgtcggt gtaggcgcgg tcggcgaaga tctcgcccgc caccttcagc ccggcgcgct
     1561 cgccggccgc atggagttcc gagaggaccg gcgcgagcag gatcaggtcc gggtcgatgg
     1621 ccctgaccgc acgcgcgacc gcgtcggcga gcgcggcgtc ctcgcaggcc tggttgttga
     1681 gcgcgccgtg tggcttgacg tgggtgacgc ggccgccttc ggccgcggcc atgccggcga
     1741 gcgcgccgac ctggtagatg atcatcgcct cgagctcggc cggcgccatc ttcatcggtc
     1801 ggcggccgaa gccctgcagg tccgggtagg cggggtgggc gccgaggctg accccggcgg
     1861 cgagcgccgt gcgcacggtg tggcgcatca ccaccgggtc gccggcgtgg aagccgcagg
     1921 cgatgttggc cgagcgcacc acctgcagca gggcctcgtc ctcgcccatc gtccaggcgc
     1981 cgaaggattc gccgaggtcg gcgttgaggt tgatggtctt gttcatgggg aggttctcgg
     2041 gtcgggagcg ttcttcaata tagcgggcga aattcggtgt cgagcgcgtg cacgacgccg
     2101 tcgaccaggt tgccggtgta cagcgccaac aggtcgatgc cgtcggccgg cagcgggcgg
     2161 atggcggtga tcagcgcgcg cgtctcggct tcctcggcgc gtgcgagctg cgcgccttcg
     2221 gcggcggtga cggtggcgaa gcgcagcgtc tggcccgggc gcagcgcggc aagccgcccg
     2281 aggtcggcgc cgatcacggt ggcgatcttg ggatagccgc cggcggtctg ggcgtcggcg
     2341 agcagcacga tcggctggcc ggcgccgggg acctggatcg agccgggcac ggtggcgtcc
     2401 gacacgatgt cggcggcgcc gctgtgttcc agcttcgcgc cttcgaggcg cacgcccatg
     2461 cggtcggcct cggcggtgac gcgatagtcg ccgccgacca gcgcttcgag cgccgcggcg
     2521 ctgaaatggt cggcctgcgg accggggaca aggcggatcg ggcgcgggtc gggctcgggt
     2581 ggctgcgtca gcacgcggtc gctgccccag gcgtcggcct cggccagcgc cagacgcatg
     2641 cctgcggcca gcgcgcgacc gctgccgtcg gcgccgccga ggccggcacg cacgtaggtc
     2701 gacgcgctgc ccatcaccgg cgccacctcc agcccggcga ccgcgaccat ggcgatgcgg
     2761 ccgctgccca tcttgcggat gcgcagcgcc tcgcccgcgg cgatcgtgac cgaacgccag
     2821 ggtgcgagct ggcggcggcc ctcgggcccg tccacctcca ccaccgcgtc gccggcgacg
     2881 gcgagcttca ccgcgccgcc gtgcgccacc acgtgcaggc caccgtcgaa gcactcgatc
     2941 accggcgcgt cctcgggccg gccggcgagc gcgttggcga ggcgcatcag gcgacggtcg
     3001 agcacgcccg cccagggcac tccgatgcgg cggaagccgc ggcggccctc gtcctggatc
     3061 gaggcgaagg cgccgggggt gacgatctcg agttcggtct gcgtgctcat gctgcgttct
     3121 ccgcgggggt cggggcgctg tccagccact gcatggggtc gaagtcggcg gtgcacgcgg
     3181 cggcctcgat ggcgcggcat tccgcggtgc ttaccgggac gaagcgcacg cggtcgccgg
     3241 cggcgagcag cgacggcgac gctcggcgcg cgtcgaacag cggcaccggg cagcgcccga
     3301 gcaggtgcca gccgccgggg ctttcccacg ggtagatcgc ggtcagcccg gtggcgatcg
     3361 ccacgctgcc tgcgggcact cgcacgcgcg gctgggcgcg gcgcggcagg cgcaggcgct
     3421 cgggcaggtc gcccatgaag gggaagccgg gcaggaagcc gagcatgtag acgaggtact
     3481 cggtgccgct gtgcagggcc accacctcgt cctcgccaat gccgatcgtg cccgccacct
     3541 cggcgaggtc gggtgcggcc tcgccctcgt agcacaccgg caggcgccag tggcggccgt
     3601 cggcgggact gccgtgctcg gccgcggcga tcagcggctg cagcacgccc agcacggtgt
     3661 cgcggtcggt ggcgagcgga tcgaagaaca ccgtcagcga gcggaaggtg ggcatggtct
     3721 cgatcacgcc cggaaggtcg cccgccgact gcaggcgcag gatggcagcg tcgagcgcgt
     3781 tgaccgcggc gagcagggcg gggtcgatga cgctgccgaa ctcgatggtg agcgcggcgt
     3841 cgccggcgtc gaggatgcgg acactcatgg cgggcttcct gtagtcagag cggggaggtg
     3901 gaggcagcgc gcgccgcctg gtcgtaacgc cccgagaccg tacgcagcaa ctgggcgagc
     3961 tcggcgatgc gacggttctc ctcggcgctg ccgctgaacc cgggcatcag gcaggcctcg
     4021 cgcacgtcgc ggtagaccag gcagatctcg cgccccttgt cggtgaccga ccagaaggct
     4081 tccttgccac gctttgcgct ttgcaccagg ccgaggccgg cgagcttgcg cagcgagtag
     4141 gagaccacgt gagtgtcttc cacgttgagc acgaagccga tgtcggccag gcgtttttcg
     4201 gtgtcgcggt gggcgacgtg gtgcagcacc agcacgtcga tcggcgtcat gtccttgacg
     4261 ccggcggcgg tcatgcaacg catcatccag cgcgcgaagg cgtgccacgc gatgatcagg
     4321 ccgaactcga actcggacac ctggggcgac ttcgccgaga cgaggtgctg tgaagaaacg
     4381 atgggaccgc tgtcgcccat gtgagcctcc gtcagtgtta tgaagacgtt ttgcgtaaaa
     4441 aacctctacg ttttgttgac aagataccca caaaatctct attgtgcaat aacggtgact
     4501 tatggatagc tggtcgccgc ctccgacaag gtgttccggg cgctgcccca cttcattcaa
     4561 tcaggagtta catccatgac cttctcgcat cctctgctca aggcgatcac cggttccctg
     4621 ctcggcctgg gcttcgtcgc cgccgcccac gcccagaccg cctgggacat gcccacgccc
     4681 tacccggcca gcaacttcca caccgagaac atccagcagt tcgccaagga ggtcgacgcg
     4741 gccaccggcg gcaagctcaa gatcaccgtc catgccaacg gctcgctgtt caaggccaac
     4801 gagatcaagc gcgcggtgca ggccggccag gcgcagatcg gcgagctgat catctcgggc
     4861 ctcgccaacg aagacgcgct ctacgcgctc gacaccgtgc ccttcctcgc caccagctac
     4921 gccgactcca agaagctgtg ggaggcctcg aagcaggcgg tcgaggcgcg cttggcgaag
     4981 aacggcctca aggtgctgta ctcggtggcg tggccgccgc aggggctgta ctcgaagacc
     5041 gagctcaaga ccatcggcga cctcaagggc atgaagatcc gctcctacag cccgaccgtg
     5101 gcgcgcatga tcgagctgat gggtggccag ccggtgaccg tgcaggccgc cgacctcacc
     5161 caggcgctgt cgaccggcgt ggtgtcggcc aacctgacct cctcggccac cggctacgac
     5221 accaagagct gggagcagct cagccactac tacgacatcc aggcctggct gccgaagaac
     5281 atcgtgttcg tgtcgaagaa ggccttcgac gccctcgacc agccggcgcg cgacgccttg
     5341 ctcaaggccg ccgccgctgc cgaggagcgt ggctggaagg tctcggaaga gaagaccgcc
     5401 tggtacgtcg agcagctcaa ggccaacaag atgcaggtgc agccggcgcc cgaggcgctg
     5461 caggccgaac ttctcaaggt cggcgagaag atgaccgccg agtgggtcga gaaggcgggc
     5521 ccggacggcc aggccatcct cgacgcttac cgcaagctga agtaagcggc tgatgcatcg
     5581 gccccgcagc agcggggcct tcacctttca ggagatcgcc catgagagcg ttcctcgatt
     5641 cgctgtaccg cctgtccggc gcgctcgccg cgatcggcat ggtggcgacg ctggtgctcg
     5701 tcacctccgg tgtcgtgacc cggccgctcg gcatctacct gcccggcacc gacgactacg
     5761 ccggctacgc gatggcggcc tgcggcttct tcgcgctcgc ctacaccttc aagcacggcg
     5821 agcacatccg cgtgagcctg ttgctcgagc gcgtcggccc gcgcatgcgc gcggcgctgg
     5881 agtggttctc gctcgcggcg ggcaccgcgg tggcggcgac gctggcgttc tacgccgtgc
     5941 gcatggtgct gcagtcgcac gagttcgagg agatctcgca gggcgtggat gccaccccgc
     6001 tgtggatccc gcagctgtcg atggcgatcg gctcggtcgt gctgctgatc gccctgctcg
     6061 acgacctggt gatgaccatg ctgggtcgtg caccggctcg actcgccacc cacagcggcg
     6121 aagccgcgcg catggaataa gaggagcgcg ccatggaagt catgattgcg gccgtgatga
     6181 tcggcctgat gctggcgctg ctcgccggcg gcgtatggat cggcctcgcc ctgatggcga
     6241 tcggcatcct cggcatgctc ggcttcacgc cgcgcgcgcc cggcgatggc atggcggtgg
     6301 cgatctggag ccacggctcg agctggacgc tgaccgcgct gccgttgttc ctgtggatgg
     6361 gcgagatcct gttccgcacc aagctgtcgg aggacatgtt caagggcctg tcgccctggc
     6421 tcgagcgcct gcctggccgc ctgctgcaca ccaacatcat cggctgcacg ctgtttgcgg
     6481 cggtgtcggg ctcgtcggcg gccacctgcg ccaccatcgg caagatcgcc ctgcccgagc
     6541 tcgagcgccg cggctatccc gagtcgatgg cgctcggcac cctggctggc gccggcaccc
     6601 tcggcctgct gatcccgccc tcgatcatca tgatcgtgta cggcgtcgcg gccgacgtgt
     6661 cgatctccaa gctcttcatc ggcggcgtgc tgcccggcat cctgctggcg acgctgttca
     6721 tgggctgggt ggtggtgtgg tcgctgatga acccgggcaa gatcccggcg cccgacctca
     6781 agaccacctt cgtcgaaaag ctcgccgcct cgaagaacct gatcccggtg atcctgctca
     6841 tcggcggcgt gctcggctcg atctacagcg gcatcgccac cgccaccgag gcggcggcga
     6901 tcggcgtgat cggcagcctc atcatcgccg ccagccagcg cacgctcaac cgcaagagct
     6961 tcttcggcgc gctgatgggc gcgacccggc tgtactgcat gatcgcgctg atcctcgccg
     7021 gctcggcctt cctgaccctg gcgatgggct acatcggcct gccgcgccac ctcgccgaat
     7081 ggatcggcgc gctcggcctc agtccggcga tgctgctggt ggcgctggcg atcttctaca
     7141 tcctgctcgg ctgcttcctc gacggcatct cgatcgtggt gctgaccatg gcagtgctga
     7201 tgccgaccat ccagagcgcg ggcatcgatc cgctgtggtt cggcatcttc gtggtggtgg
     7261 tggtggagat ggcgcaggtc acgccgccgg tgggcttcaa cctcttcgtg ctgcagggcc
     7321 tcaccgggcg cgacatgacg gtgatcgcgc gctacgcgct gccctacttc ctgctcatgg
     7381 tggtcgcggt ggtgctgctg tacaccttcc ccggcctggt gacctggctg ccgggccaca
     7441 tggtggggtg aggtcgtgag ccgccgccgg agctcactcg ccgggcgcgg gcgtcgcgtc
     7501 cgcggacggc ccggcggcga gctccgcggc gcgcgcctcg gccaccagcc agtcgcgcac
     7561 cgtggccacg cgcgggtcgg cgagcgcgcc ggccgaatgg atgacgcagt agcgcttgcc
     7621 ggtgcgcacc gactgcgcga agggcgccac caggcggccg ctgtcgagct cgtcggtgat
     7681 cagggtgcgg cgcgcgatcg ccacccccat gccggcgatc gcgcactgca tggtgatgtg
     7741 gttgcggttg aacatgtagc cccgccgcac ctccacctgc ggcgcgccga tcgccttcag
     7801 gtagcgctcc cactcggcgt agggcgggct gccgcgccag gcggtcatgt cgtgcagcaa
     7861 cgggtagtgg cgtaggtcct cggcgccgag cagcggcggg cgaccttcga gcaggcgggg
     7921 cgagcacacc gggaagatct cctcctccag cagcacggtg ctctggaagc cggggtaggt
     7981 gccgtcgttg aggtcgatcg cgaggtcgaa ctcgccgtcg cgcagcgaat aggtgctgtc
     8041 ctcggcctcg acctgcagct cgatctgcgg aaagcgcgcc atcaggcgcg gcaggcgcgg
     8101 taccagccag gtggcgagga aggagggcag ggtgcgcacc cgcaccacgc cgctgagcgc
     8161 gccgccgcgc aggcgtccga tggcgagatc gaccgcggcg taggccggat cgaccgcggt
     8221 gagcaggcgc ttgcccgcgt cggtgagctc gagccggcgc ggcaggcggc ggaacaggcg
     8281 ctggccgagc cagtcctcga gcagcttgat ctgctggctg accgcgccgg tggtgatgct
     8341 gagctcctcg cccgcgcggg tgaaggacag gtgatgcgct acggcgagga agacgcgcag
     8401 ccgggtatgg atctgcgaag gtgcgctcgt ggacatggtt tagttttgct aaagaaaaga
     8461 tcaaaaacaa tcgattgagt gcccgaatct tccgctggaa aatcttgttc atgcaccgat
     8521 aagtattttc gtgcttagca gaattaaatc aacacgccgt tttcccccgg agtctcccat
     8581 gtccatcagc gtactcgacc tgttcaagat cggtgtcggt ccttccagct cgcatacggt
     8641 cgggccgatg cgggccgcgc atgatttcgt cgtggagctg cagcgccgcg gcctgctcga
     8701 ccaggtgcgg cgcatcgagg ccaggctcta cggctcgctg tcggcgaccg gggtcggtca
     8761 cggcaccgat cgcgcggtgg tggccggcct gatgggcgcg cgcccggacg aggtcgatcc
     8821 cgacttcctc gtgggtgcgg tcgacgcggt gcgcatcgac ggcgaactgc cactcgccgg
     8881 cacgacgacg gtgcccttcg actgggcgcg cgacctgcgc ctgctgccgg tgagcctgcc
     8941 ctaccatccc aacgcgatgc gcatcgccgc gcacggcgag gccggcgtgc tgtacgagaa
     9001 cacctactac tcggtggggg gcggcttcgt ggtcgacgag gcgcaggcgc agtccggcgc
     9061 ggcggccgag gccgaggtgg ccgtgcccta tcccttcgac accggcgccg agctgctcgc
     9121 ccagtgccgc cgccacggcc tgcgcatcag cgagctgatg ctggccaacg agtcggcctg
     9181 gcgcagcgag gcggagacgc gcactgcgct gctgcgcatc tgggaggtga tgcgtgcctg
     9241 cgtgacgcgc ggcgtcggcc acgagggcgt gctgcccggc gggctcaacg tgcgccggcg
     9301 cgcgccggcg ctgtaccgca agctcagcga gcaggcgagc gggcgcaaca tgatcagcga
     9361 ctccatgacc gccctcgact gggtcaacct ctacgcgctc gcggtcaatg aagagaacgc
     9421 cggcggcggc cgtgtcgtca ccgcccccac caacggcgcg gccggcatca ttccggcggt
     9481 gatgcactac tacatgaagt tcatgcccgg cagcgacgag cgcgacgtgg agaacttcct
     9541 cctcgccgcc gccgcggtgg gcgcgctttg caagaagaat gcctcgatct ccggcgccga
     9601 ggtcggctgc cagggcgagg tcggatccgc atgcgcgatg gccgcggccg gtctcgccga
     9661 agtgctcggc ggcacccccg
//
LOCUS       DAOTIN010000121         9573 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_8497_length_9573_cov_9.566821, whole genome shotgun sequence.
ACCESSION   DAOTIN010000121 DAOTIN010000000
VERSION     DAOTIN010000121.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 9573)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 9573)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9573
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_8497_length_9573_cov_9.566821"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1182
                     /locus_tag="P5537_14030"
     CDS             <1..1182
                     /locus_tag="P5537_14030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite transporter"
                     /protein_id="HRV79204.1"
                     /translation="TPTLIAAFLYFDLAFMVWVILGPLAVGIAADLGLSHAQKGLIVA
                     TPVLAGAILRMVMGVVVDRLSPKKAAIIGQLIVIAALAYAWLAGVHSFGEVLVLGVFL
                     GVAGASFAAALPLASRWYPPEHQGTAMGIAGAGNSGTAFAALFAPGLAMAFGWHNVFG
                     LALIPLVIVLVAFCFMAKDAPDAPPPKRFAEYLAVLKDKDAWWFMFFYSVTFGGFVGL
                     ASSLVIYFNTQYGLDPKMAGYFTAACVFAGSLVRPIGGNVADRIGGVKSLTAMYILAA
                     IFLAIVSVGLPEAWMALAVFVGAMLALGMGNGAVFQLVPQRFRREIGVMTGLVGMAGG
                     IGGFYLASSLGFARQLTGSYQAGFLIFAALAVFALVGLTAVKTRWRTTWGAAHLTSAK
                     I"
     gene            1276..>1907
                     /locus_tag="P5537_14035"
     CDS             1276..>1907
                     /locus_tag="P5537_14035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein phosphatase 2C domain-containing
                     protein"
                     /protein_id="HRV79205.1"
                     /translation="MATALEVELGHATRPGPRPANEDFVAAAMPEGAERAAKGVLLAI
                     ADGVGGHAHGREAAEYTVRSLLADYFSTAHTWSVQKSLDTVLGAANRWLLAQSARSVE
                     TAGMATTLTALVLRGRRWHLAHVGDSRAYLWRDGALVRLSEDHTWPHPELNNVLRRAV
                     GLESRLLVDHDDGELAAGDVFVLLTDGVWNALGEVEIAAVLARHVGEEKG"
     assembly_gap    1908..2007
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            2397..3209
                     /locus_tag="P5537_14040"
                     /pseudo
     CDS             2397..3209
                     /locus_tag="P5537_14040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584887.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein kinase"
     gene            complement(3224..6004)
                     /locus_tag="P5537_14045"
     CDS             complement(3224..6004)
                     /locus_tag="P5537_14045"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79206.1"
                     /translation="MSRTVRDAPKRPSGNRVLALGLLMSASASFQLTAFLQVSLTPSW
                     LLPVLAAWLAQRHGIAVLRDAWPLVILPTLGVNFGHGIGFSFGVPSATLLLALVVAAA
                     ADARLRLPPLEHWLRGDTAWPAASALCLLVVSALEAGSWRVGTWRLDLLALPGVLVML
                     AAIRWEAVAAAAWPTAPRRYAGAFGLLVAAIGLAGLVLSGAIVLGPLQLRVGSYSPAP
                     FLAILCFGLVVLGFARARNVAGLLLAGLVLDRLLALGDMPASFAMETEWRLLDWGALF
                     ASLAATLAGQVLRPFFADGAFMPTSVRPVLHLLLAWLALLLCPLLLTGFGVSSGTAGL
                     WLVAALAFATGTYSRERSLVFVPPLLMFLWLLAALFDPAGGPGRATGMLATLGTLGFT
                     FALCGAFLAYSRALAALGATRAASAAQAEAIERVDLSPLAEVVEQVDRSATWRSFLVA
                     AAPFVVAWQLFELYGFRIVVGDISEAFGEPPMLEAWHYAIAAMLALAPFAFAFWDWLD
                     RQDRFRLLALVSASIAGAIAWQLFGALLGAGVRELFGDFGDTPLEAGGILAFSVLLLG
                     SGLLAGTDRRVARPLFLALCTLTGVAVVSALAWALGEGTVEAQELPRLLAEPVVILLI
                     CVALARFIRLRLLLAGDRPREWLFGALRDKGFWVRMAAAAGLPSSSWRLGALSAPAFW
                     ALFAARFVVYTGGVLARSWAAIGAVVILFGHLLFHAGKRLSAREMWRPRTPAAADRPI
                     LFLRGFDDDQCRYRRRPWQLLARWLDLWSFRQNLDEAMVDELAQFGPVVALGRPGDTR
                     TPFGAQRHYSADADWQQTLADAARSAQAIVLVASDSPGVQWEYALLKNEAMLDKVLLM
                     FRPDGEHTAANRHAAEWMCPGGGGAVDAAIAAGLQPVSLRLIQGRPILAASRAANAAA
                     GVLALRLHFERA"
     gene            6423..9212
                     /locus_tag="P5537_14050"
     CDS             6423..9212
                     /locus_tag="P5537_14050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HRV79207.1"
                     /translation="MSHTLPETAPPSPAGRRSVPVRAAAPGETRPTCPYCGVGCGVLI
                     EHDGARITGVRGDPAHPANFGRLCTKGATLHLTAGHDTRLLHPEYRARRGQARARIGW
                     EAAIEVAARRFAEVIAEHGPDAVAFYISGQLLTEDYYVFNKAMKGLIGSNNVDTNSRL
                     CMSSAVAAYKATLGADAPPCCYEDFDHADTILIAGANPAWAHPVAFRRIEQARARRPG
                     MKIIVVDPRRTDTAAMADLHLAILPGTDVWLFDAMLHVLLREGLVDQAWIAAHTEGFE
                     ALRAHVRGVSPAVAAAVCGVAAEDIVTAARWWGEAPAALSLWCQGLNQSTHGTHNGAA
                     LIALSLATGKIGRPGCGPFSLTGQPNAMGGREVGGLANLLPAHRDLANPAHREEVARL
                     WGVDSVPAEPGLTAVELFRAAREGRIKAIWIACTNPAQSMPEQALVHEALAACEFVVL
                     QEAFAGTETAAFADLVLPAATWGEKEGTVTNSERRISRVHAAVPAPGEARADWRIVCD
                     FARALAPRIGKPQAAAMFAYDSAEAVFAEHVASTAGRDLDITGLDYCVLEREGPQQWP
                     FAAGARVEEAGARARLYADARFATPNGRARFVVPSRTLTAEATGVRYPLALTSGRLRD
                     QWHGMSRSGKVARLYGHADEARIELHPRELARRGLADGELVRVSSRHGALVLRVAASD
                     ALRPGMAFVGMHWGRRVLNSAGINLLFGGACDPLSKQPELKHAAVRIEPVELPNRMLL
                     VRAERCGRSAAEEAALLSPWLERFAYASLALAGRDTPAVVMRVAHERPIPPAWLAELD
                     ALLGLDGVLSYADPARGISKRALIEDDRLVGLRLTGETAAAGWLSEAVVERRDAVALR
                     PWLLAPLATPPAGGGGRGRVVCNCLNVSESDIAAAIAEGAGVRDFDALQARLRCGTSC
                     GSCVPEIRRMLAEGR"
BASE COUNT         1383 a         3403 c         3459 g         1228 t
ORIGIN      
        1 acgccgacgc tgatcgccgc cttcctctac ttcgacctcg ccttcatggt gtgggtgatc
       61 ctcggcccgc tcgcggtcgg catcgccgcc gacctcgggc tgtcgcacgc gcagaagggc
      121 ctcatcgtgg ccacgccggt gctggcgggg gcgatcctgc gcatggtgat gggcgtggtg
      181 gtcgatcgcc tgtcgcccaa gaaggccgcg atcatcggcc agctgatcgt gatcgccgct
      241 ctcgcctacg cctggctggc gggcgtgcat tcgttcggcg aggtgctggt gctgggggtc
      301 ttcctcggcg tcgcgggcgc gtccttcgcg gcggcgctgc cgctggcctc gcgctggtat
      361 ccgccggagc accagggcac ggcgatgggc atcgccggtg ccggcaactc gggcaccgcg
      421 ttcgcggcgc tgttcgcgcc cgggctggcg atggccttcg gctggcacaa cgtgttcggc
      481 ctggcgctga tcccgctggt gatcgtgctg gtggccttct gcttcatggc caaggacgcg
      541 cccgacgcgc cgccgcccaa gcgctttgcc gagtacctcg cggtgctcaa ggacaaggac
      601 gcgtggtggt tcatgttctt ctattcggtg accttcggcg gcttcgtcgg cctggcctcg
      661 tcgctggtga tctacttcaa cacccagtac gggctcgatc cgaagatggc gggctacttc
      721 accgcggcct gcgtgttcgc cggctcgctg gtgcgcccga tcggcggcaa cgtggccgac
      781 cgcatcggcg gggtgaagtc gctgaccgcg atgtacatcc ttgcggcgat cttcctcgcc
      841 atcgtcagcg tcggcctgcc cgaggcgtgg atggcgctgg cggtgttcgt gggcgcgatg
      901 ctggcgctgg gcatgggcaa cggcgcggtg ttccagctcg tgccgcagcg cttccgccgc
      961 gagatcggcg tgatgaccgg cctggtcggc atggcgggcg gcatcggcgg cttctacctg
     1021 gcgtcctcgc tcggcttcgc gcgccagctc accggcagct accaggccgg cttcctgatc
     1081 ttcgcggcgc tggcggtgtt cgcgctcgtg ggcctcaccg cggtgaagac gcgctggcgc
     1141 acgacctggg gcgcggcgca cctgacctcg gcgaagatct gagcaagggc gggcatcgtg
     1201 cgtgcgatcg attccttggc acccgccggc agcccggccg cgggccgcgc cacgccgacc
     1261 ggggctgcgc ggccgatggc gaccgcgctg gaggtcgagc tcggccacgc caccaggccc
     1321 ggcccgcgcc cggccaacga ggacttcgtc gccgccgcca tgcccgaggg cgccgagcgc
     1381 gccgccaagg gcgttctgct ggcgatcgcc gacggcgtcg gcggtcacgc gcacggccgc
     1441 gaggcggcgg agtacaccgt gcgtagcctg ctcgccgact acttctccac cgcccacacc
     1501 tggagcgtgc agaagtcgct cgacaccgtg ctcggcgccg ccaaccgctg gctgctcgcg
     1561 cagtccgcgc gcagcgtcga gaccgccggc atggcgacca cgctgaccgc gctggtgctg
     1621 cgcggccggc gctggcacct cgcccacgtg ggcgactcgc gcgcctacct gtggcgcgac
     1681 ggcgcgctcg tacgcctgag cgaggaccac acctggccgc atcccgagct gaacaacgtg
     1741 ctgcgccgcg cggtcgggct ggagtcgcgc ctgctggtgg accacgacga cggcgagctg
     1801 gcggcgggcg acgtcttcgt gctgctgacc gacggggtgt ggaacgcgct cggcgaggtc
     1861 gagatcgccg cagtgctcgc gcgccatgtg ggggaggaga agggaagnnn nnnnnnnnnn
     1921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1981 nnnnnnnnnn nnnnnnnnnn nnnnnnncat cgacaccgtc ccaacccgcg ccggttcatg
     2041 taggagcgcc ggcaggcgcg aatgcggcgt cgattctccc cgaccacgtc gccgaccgta
     2101 cggcctcatt cgcggctgcc gccgctccta catcgcccca acccgcgtcg acatcgcccc
     2161 aacccgcgtc gacaccgtcc caacccgcgc cggttcatgt aggagcgccg gcaggcgcga
     2221 atgcggcgtc gattctcccc gaccacgtcg ccgaccgtac ggcctcattc gcggctgccg
     2281 ccgctcctac atcgccccaa cccgcgtcga catcgcccca acccgcatcg acaccgtccc
     2341 aacccgcgcc ggttcatgta ggagcgccgg caggcgcgaa caccgccgcg tgctgggtcc
     2401 tcaagacctt gctgcccgcc cacgaacacg acgaggacgc gcggcgcgcg ctggtgcgcg
     2461 aggagtggct cgcgcgccgg gtgccggcgc aagggtttcc gcaggtggcc gactggcccg
     2521 cgcgcgcgca cctgtactac ctgatgagct ggcacgaggg cgagagcctg aaggccctgc
     2581 tcgcgcgcgg cgagcgtctg cgcgcgcacg aggtggccga gctcggcgcg cgcatgctgc
     2641 gcctggtcgg cgtgctgcac cggcggggca tcgtgcatcg cgacatcaag cccgacaacc
     2701 tgcacctcgg ccgcgacggc gtgctgcgcc tgctcgacct cggcgtggcg gcgagcgagg
     2761 cggaggacct gtgcgagatc aacaacccgg gcacgccgtc ctacatggcg cccgagctct
     2821 tcgccggcca gccggccagc gaggcctccg acctctacgc ctgcggggtg acgctgtacg
     2881 agctgctcac gcgcaagttc ccctacggcg aggtcgagcc cttccagcat ccgcgcttcg
     2941 gcgagccggt gccgcccacc cgtcaccgcc ccgacacgcc ggcctggctg gaggcggtgc
     3001 tgctcaaggc gtgcgcgcgc atgcccgacg cccgcttcga gaccgccgag gagttccgcc
     3061 tcgcgctcga gcgcggcgcc tggcagccgc tcgccgtgcc gcgccgcacg ccgctgctcg
     3121 agcgccggcc gacgctggcg ctgaagctgc tcgcgctcgg ctcgctgctg ctgaacctgg
     3181 tgctgctgtt cctgctgacc cgatcctgaa ccgccccagc acgctacgcg cgctcgaagt
     3241 gcagccgcag cgcgagcacc ccggccgcgg cgttggcggc gcgcgatgcg gcgaggatcg
     3301 gccggccctg aatgagccgc aggctcaccg gttgcaggcc ggcggcgatc gccgcgtcga
     3361 ccgcgccgcc gccgccgggg cacatccatt cggccgcatg acggttggcc gccgtgtgtt
     3421 cgccgtcggg gcggaacatc agcaacacct tgtcgagcat ggcctcgttc ttcaacagcg
     3481 cgtattccca ctgcaccccc ggcgagtcgc ttgccaccag cacgatggcc tgcgccgagc
     3541 gggcggcgtc ggccagggtc tgctgccagt cggcgtcggc ggagtaatgg cgctgcgcac
     3601 cgaagggcgt gcgcgtgtcg cccggtcgcc cgagggcgac caccgggccg aactgtgcga
     3661 gctcgtcgac catggcttcg tcgaggttct ggcggaagga ccacaggtcg agccagcgcg
     3721 cgagcaactg ccatgggcgg cggcgatagc ggcattgatc gtcgtcgaag ccacgcagga
     3781 acaggatcgg gcgatctgcc gcggcgggtg tgcgcggccg ccacatttcg cgcgcactca
     3841 ggcgcttgcc ggcgtggaac agcaggtggc cgaagaggat cacgacggcg ccgatcgccg
     3901 cccacgagcg tgcgagcacg ccaccggtgt agacgacgaa gcgcgccgcg aacagcgccc
     3961 agaaggccgg cgcggagagg gcgccgaggc gccacgagga ggatggcaag cccgccgcgg
     4021 cggccatccg cacccagaag cccttgtcgc gcaatgcgcc gaacagccat tcgcgtgggc
     4081 ggtctccggc cagcagcagg cgcaggcgga tgaagcgggc cagcgcaacg cagatgagga
     4141 ggatcacgac cggctcggcg agcagccgcg gcagttcctg cgcttcgacc gtgccctcgc
     4201 caagcgccca cgcgagcgcg gagacgacgg ccacgcccgt cagggtgcac agcgcgagga
     4261 aaagcgggcg ggcgacacgg cggtcggtgc cggccaggag cccggagccg agcagcagca
     4321 ccgaaaaggc caggatgccg ccggcctcga gcggggtgtc gccgaaatcc ccgaacagct
     4381 cgcggacgcc ggcgccgagc aaagcgccga aaagctgcca ggcgatcgcg cccgcgatgc
     4441 tcgcgctcac cagcgcgagc aggcggaagc ggtcctggcg gtcgagccag tcccagaacg
     4501 cgaaggcgaa gggtgccagc gcgagcatgg ccgcgatcgc atagtgccag gcctccagca
     4561 tcggcggctc gccgaaggcc tcgctgatgt ctccgacgac gatgcggaag ccgtacagct
     4621 cgaacagctg ccacgccaca acgaagggcg cggcggcaac gaggaaggag cgccaggtcg
     4681 ccgagcgatc gacttgttcg accacctcgg cgagcggcga gaggtcgacg cgctcgatcg
     4741 cctcggcctg cgccgctgat gccgcgcgcg ttgcgccgag tgcggcgagc gcgcggctgt
     4801 acgcgaggaa ggcgccgcag agtgcgaacg tgaagccgag cgtgccgagc gtcgccagca
     4861 tcccggtcgc gcgccccggg ccgcccgcgg ggtcgaagag cgcggcgagc agccacagga
     4921 acatcagcag gggcgggacg aagaccaggc tacgctcgcg cgagtacgtt ccggtcgcaa
     4981 acgcgagggc cgccaccagc cacagccccg ccgtgcccga cgacacgccg aagccggtca
     5041 gcagcagggg gcacagcagc agcgcgagcc aggcgagcag cagatgcagg acggggcgga
     5101 cgctggtcgg catgaacgct ccgtccgcga agaaggggcg cagcacctgg ccggcgagcg
     5161 tcgccgcgag gcttgcgaac aaggcccccc agtccaggag gcgccattct gtctccatgg
     5221 cgaaggatgc gggcatgtcg ccgagcgcga gcaggcgatc gagaacgagg ccggcgagca
     5281 acaggcccgc cacgttgcgc gcgcgcgcga atccgagcac gacgaggccg aagcacagga
     5341 tggccaggaa gggcgccggg ctgtagctgc ccacgcgaag ctggagtggc ccgaggacga
     5401 tcgcgccgga gaggaccagc ccggccagcc cgatcgccgc gaccagcagg ccgaacgcgc
     5461 ccgcgtagcg gcggggcgct gtcggccagg cagcggccgc caccgcctcc cagcggatgg
     5521 cggcgagcat cacgagcacg ccaggaaggg cgagcaggtc gaggcgccat gtaccgaccc
     5581 gccaagagcc ggcttccagc gcggagacga ccagcaggca cagggccgag gccgccggcc
     5641 acgcggtgtc gccccgcagc cagtgctcga ggggaggcag gcgcagccgc gcgtccgccg
     5701 ccgcggcgac gaccagcgca agcagcagcg ttgcgctcgg gaccccgaag ctgaacccga
     5761 tgccatggcc gaagttcacg ccgagcgtgg gcagtatgac gagcggccag gcgtcgcgca
     5821 gcacggcgat gccatgacgt tgtgcgagcc acgccgccag cacgggcagg agccagctcg
     5881 gggtgaggga gacttgcagg aatgcggtga gctggaagct ggcgctggcg ctcatcagca
     5941 gaccgagcgc caggacccgg ttccccgagg gccgcttcgg ggcgtcgcga actgttcggg
     6001 acatcgaggg gctccctgag cgtgttggcg ccgcgcgcgc aattcagcac ccgtgcccgg
     6061 ctgcgaactg ggcgactgct tcgtttcact ataggccggc gcgatcggga tcgtgcatcg
     6121 cagatcgggg cctcggccac ctgggttggc gtcacgcggg cggcaggaag agcgcggggt
     6181 tcggtgcccg ccggcgtgcg ctgcgcggat tcgcgcaccg tgtgcgtgca ccgcaccccg
     6241 acacggtgca tgaccgcgac cgatcctgcg ccgcaagcgc ccgcaggatg cgggaatcgt
     6301 cgctggcaca cggcttgcat caattttgtc catacagcgt cggactcgcc aatgggggtg
     6361 ggtcggtcgg gcaaggaggt tcgcgctgac ccgattccga ccatccaagg acgaggcaaa
     6421 ccatgtccca caccctgccc gaaacggccc cgccttcgcc cgccggccga cgctccgttc
     6481 cggtccgcgc cgcggcgccg ggagagaccc gccccacctg tccctactgc ggcgtcggct
     6541 gtggcgtact catcgagcac gacggcgcgc gcatcaccgg tgtgcgcggc gatcccgcgc
     6601 atccggccaa cttcggccgc ctgtgcacca agggcgcgac gctgcacctc accgccggcc
     6661 acgacacccg gctgctccac cccgaatacc gcgcccgccg cggccaggcg cgcgcgcgca
     6721 tcggctggga ggcggcgatc gaggtcgccg cgcggcgctt cgccgaggtg atcgcggagc
     6781 acggcccgga cgcggtcgcc ttctacatct ccggccagct cctcaccgag gactactacg
     6841 tcttcaacaa ggcgatgaag gggctgatcg gcagcaacaa cgtcgacacc aactcgcgcc
     6901 tgtgcatgtc gagcgcggtc gcggcctaca aggccacgct gggcgccgat gcgccgccgt
     6961 gctgctacga ggacttcgac cacgccgaca cgatcctgat cgccggcgcc aacccggcgt
     7021 gggcgcaccc ggtggccttc cgccgcatcg agcaggcgag ggcgcggcgg ccggggatga
     7081 agatcatcgt ggtcgatccg cgccgcaccg acaccgcggc gatggccgac ctgcacctgg
     7141 ccatcctgcc cggcaccgat gtctggctgt tcgacgccat gctgcacgtg ctgctgcgcg
     7201 aagggctcgt cgaccaggcc tggatcgccg cccacaccga gggcttcgag gcgctgcgcg
     7261 cgcacgtgcg cggggtgagc ccggcggtgg ccgcggcggt gtgcggggtg gcggcggagg
     7321 acatcgtcac cgccgcgcgc tggtggggcg aggcgccggc ggcgctgtcg ctgtggtgcc
     7381 agggcctcaa ccagtcgacg cacggcaccc acaacggcgc cgcgctgatc gcgctctcgc
     7441 tcgccaccgg caagatcggc cgccccggct gcgggccgtt ctcgctcacc ggccagccca
     7501 acgcgatggg cgggcgcgag gtcggcgggc tggcgaacct gctgccggcg catcgcgacc
     7561 tggcgaatcc cgcccatcga gaggaggtgg cgcggctgtg gggcgtggac agcgtgcccg
     7621 ccgaacccgg gctgaccgca gtggagctct tccgcgccgc gcgcgagggc cgcatcaagg
     7681 cgatctggat cgcgtgcacc aacccggcgc agtccatgcc cgagcaggca ctggtgcatg
     7741 aggcgctcgc cgcctgcgag ttcgtcgtgc tgcaggaggc attcgccggc accgagaccg
     7801 cggccttcgc cgacctggtg ctgccggccg ccacctgggg cgagaaggag ggcacggtga
     7861 ccaactccga gcgccgcatc agccgtgtgc acgcggccgt gccggcgccg ggcgaggcgc
     7921 gcgccgactg gcgcatcgtg tgcgacttcg cgcgcgcgct cgcaccgcgc atcggcaagc
     7981 cgcaggcggc agcgatgttc gcgtacgact cggcggaggc ggtcttcgcc gagcacgtcg
     8041 ccagcaccgc cgggcgcgac ctcgacatca ccgggctgga ctattgcgtg ctcgaacgcg
     8101 aggggccgca gcagtggccg ttcgcggcgg gggcgagggt cgaggaggcc ggcgcgcggg
     8161 cccgcctcta cgccgacgct cgcttcgcca cgccgaacgg acgggcgcgc ttcgtcgtgc
     8221 cctcgcgcac gctcaccgcc gaggcgaccg gcgtgcgcta cccgctcgcc ctcaccagcg
     8281 gccgcctgcg cgaccagtgg cacggcatga gccgcagcgg caaggtggcg cgcctgtacg
     8341 gccacgcgga cgaggcgcgc atcgagctgc acccgcggga gctggcgcgg cgcggcctgg
     8401 ccgacggcga gctggtcagg gtgtcgagcc ggcacggtgc gctggtgctg cgcgtggccg
     8461 cgtcggatgc gctgcggccc ggcatggcct tcgtgggcat gcactggggg cggcgggtgc
     8521 tgaactcggc cgggatcaac ctgctcttcg gcggcgcgtg cgatccgctg tcgaagcagc
     8581 cggagctcaa gcacgcggcg gtgcgcatcg agccggtcga gctgcccaat cgcatgctgc
     8641 tggtgcgtgc cgaacgctgc gggcgcagcg cagccgagga ggccgcgctg ctgtcgccct
     8701 ggctggagcg cttcgcctac gcctcgctcg cgctcgccgg ccgcgacacg cccgcggtgg
     8761 tgatgcgcgt ggcgcacgag cgtccgattc cgcccgcctg gctcgccgag ctcgacgcct
     8821 tgctcggcct cgacggcgtg ctgtcgtacg ccgaccccgc gcgcgggatc agcaagcgcg
     8881 cgctgatcga ggacgaccgc ctggtcgggc tgcgcctgac tggcgagacc gcggccgcag
     8941 gctggctgag cgaggcggtg gtggagcgcc gcgacgcggt ggcgctgcgc ccgtggctgc
     9001 tggcgccgct cgccacgccg ccggcaggag gcggggggcg cgggcgggtg gtgtgcaact
     9061 gcctgaacgt gtccgagagc gacatcgcag cggcgatcgc cgagggggcg ggcgtgcgcg
     9121 acttcgacgc gctgcaggcc aggctgcgct gcggcacgtc ctgcggttcg tgcgttcccg
     9181 agatccgccg catgctcgcc gagggacgct gaaaagaaaa agcccgggcg tcttgcgagg
     9241 cccgggcaaa tccacaccaa aggaggaggg tggaggagac aggtgcgata gtagagaaag
     9301 tttttgtgcg gtgcaacaaa aaataatgct tcagctataa ggccagtttc tagagtttgg
     9361 cccaatacat ccccgcccaa gccggtttca tgcctgcccg cccggggggc cgtgacgctc
     9421 caaaaaacgc gatctccccg gcctccgcga tgcccctgta ggagcgccgg caggcgcgaa
     9481 agcggcggtg ggaggcgcaa cgcgcgtcca ttcccgctcc gcccaattcg cgcctgccgg
     9541 cgctcctaca tgaaaccgac gccacgaaca ccg
//
LOCUS       DAOTIN010000122         9546 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_8532_length_9546_cov_9.001370, whole genome shotgun sequence.
ACCESSION   DAOTIN010000122 DAOTIN010000000
VERSION     DAOTIN010000122.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 9546)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 9546)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9546
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_8532_length_9546_cov_9.001370"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..190)
                     /locus_tag="P5537_14055"
     CDS             complement(<1..190)
                     /locus_tag="P5537_14055"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79208.1"
                     /translation="MVHDMVGVSRAGSDVGAVRDGSCRSAGRRESSGSMPAALPASRD
                     AGSEPEKHLISASRVTDMR"
     gene            complement(314..937)
                     /gene="rhtB"
                     /locus_tag="P5537_14060"
     CDS             complement(314..937)
                     /gene="rhtB"
                     /locus_tag="P5537_14060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine/homoserine lactone efflux protein"
                     /protein_id="HRV79209.1"
                     /translation="MSWTMWLAFLAAALVIAVSPGPGAVLSMSTGLRYGYGAALRAIA
                     GLQIALLLQLGVVALGLGAVLATSETAFAVVKFAGAAYLIWLGVQKWRSPPEPIGGDG
                     EGQRVQSRRQLYAQGILVNLTNPKAIVFIAALVPQFIVPDRPQWPQFAIIGATMVAVD
                     MMVMSCYALLATRFRPLLRNPRLLRLQNRIFGGLFVGAGAMLAASSR"
     gene            complement(985..1791)
                     /locus_tag="P5537_14065"
     CDS             complement(985..1791)
                     /locus_tag="P5537_14065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HRV79210.1"
                     /translation="MTFDLWWLAYPVLGAAVGFFAGLLGVGGGGIMVPMLTTFFLAQG
                     FPQSQVVHMALGTSMAAIVLTSVSSLRAHHARGAVRWDVVRAITPGILVGTFAATFVA
                     SRVSTVPLAIFFAVFMAYVSIQMLLNIKPKPSRELPGALGMSAAGLGIGGVSALVAIG
                     GGSLSVPFMTWCNVKMQNAIGTSAAIGLPIALAGTVGYLVNGWGAQDMPALTFGYVYL
                     PALVLVSLVSTFFAPLGAKLAHRLPVATLKKVFAGMLVLLCAKMLHSIFA"
     gene            2109..3851
                     /locus_tag="P5537_14070"
     CDS             2109..3851
                     /locus_tag="P5537_14070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004819 - glutamine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006425 - glutaminyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HRV79211.1"
                     /translation="MKPEKNPATPAAEAPVVSNFIRSIIDEDNRNGKWGGRVETRFPP
                     EPNGYLHYGHAKSICLNFGLAEAYGGVCHMRFDDTNPEKEEQEYVDAILEAVHWLGFE
                     WGEHLYFASDYFDRMHDCAISLIQAGKAYVDSQSAEEMRANRGTLTEAGKDSPYRNRS
                     VAENLDLFARMRAGEFAEGTHILRARIDMASPNINLRDPAIYRIRHATHHRTGDAWCI
                     YPMYTFAHPIEDAIENITHSVCTLEFEDQRPFYDWLLDALATEGRFPRPLPQQIEFAR
                     LNLTYVVLSKRKLIQLVNEGHVDGWDDPRLPTLVGARRRGFTATGFRRFAERIGVSKA
                     DSWIDMSVLEECMRDDLNEAAERRVAVLDPLKLVLTNYAEGESELCQAPNHPLKPELG
                     KRDMPFSRELWIEREDFMEEPVKGFHRLYPGNMVRLRYGFVVRCTGCEKDADGTITAV
                     LAEYMPDSKSGTPGADNYKVKGNLHWVSVAHGYEAEVRIYDRLFAHPHPGQRREGDAP
                     DFERDFLTDINPDSKRIITAYLEPALKDARPEEHFQFERHGYFVADRVDSQPGAPVFN
                     RTVTLKDSWAKGGK"
     gene            3876..4208
                     /locus_tag="P5537_14075"
     CDS             3876..4208
                     /locus_tag="P5537_14075"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002932713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HRV79212.1"
                     /translation="MAIATRTTDPIAASLACLRCHLPPGSRVIVFGSQARGEARDDSD
                     LDLLVVEPEVRNRFDEMARLASLLGRELIPADVVVMSDEAFEQERAQPNTLAWRAARE
                     GRIHAFPQ"
     gene            4192..4611
                     /locus_tag="P5537_14080"
     CDS             4192..4611
                     /locus_tag="P5537_14080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEPN domain-containing protein"
                     /protein_id="HRV79213.1"
                     /translation="MHSPSELALGLLHRARDDGYVVDRLAQDPAAPDWVIGFHAQQAV
                     EKAIKAVLANAKVVFPRTHNIAMLLALLQQNGIQAPDQDVFLERLTPFGVAARYDREL
                     DQSFSLNRERTRLEILALLDWAEAMLSNAKNGSAGSP"
     gene            4970..5269
                     /locus_tag="P5537_14085"
     CDS             4970..5269
                     /locus_tag="P5537_14085"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF016362.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HRV79214.1"
                     /translation="MKLDRIYLQAKRWADAPVGGPDIDGFLGALAKHGANRGVFVTTS
                     RFTQDARRAVELPHLRLVLIDGEELARLAVEHNVGVSVKRKIELKRLDTDFFDDL"
     gene            5281..6429
                     /locus_tag="P5537_14090"
     CDS             5281..6429
                     /locus_tag="P5537_14090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HRV79215.1"
                     /translation="MKTLRPILLLALLAALAGAGGWWLTRPTPVEVVVHEVARGTVEA
                     TLTNTRAGEVEACQRAKMATIAGGRIEWLGVEEGDRVEAGQVLMRLWHGDLDARAAVA
                     RAQLATTRQRVHEACTVAANAEREAARQAQLMRRGFVSASAEEKARTEARARRAACDT
                     AQADVATAAAQLTATETERQRLVLVAPFAGTVAKISGELGEYATPSPPGVPMPPAIDL
                     IDDSCLYVKAPMDEIDAPKIQPGLPVRITLEAIPGKVFAGTVRRVAPYITAVEKQART
                     VAVDVDFVRPDEARGMLVGYSTDVEIVLATRAEVLRIPTGALREGGKVLVVEGDTLVE
                     RTLQTGVANWEFTEVVSGLDAGERIVTSLEREGVVAGAKVLARPAQAR"
     gene            6492..7223
                     /locus_tag="P5537_14095"
     CDS             6492..7223
                     /locus_tag="P5537_14095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV79216.1"
                     /translation="MAQIELEHIDRIFKLGDSEVHALRDITLRIEAGEYVAVMGPSGS
                     GKSTLLNLLGLLDRPNAGAYRLEGRDVTTLSADEQAAVRSARIGFVFQSFHLVPRLSA
                     AENIGLPLVLAGVPAAERAPRVARALQDFGLEGRARHRPDELSGGQRQRVAIARATIM
                     RPAMLLADEPTGNLDRATGHEVTALLEALNAAGTTLIVVTHDPAMGERARRRILMEDG
                     AIRQELQAAAAAPEAPGSGSTAPPP"
     gene            7220..8428
                     /locus_tag="P5537_14100"
     CDS             7220..8428
                     /locus_tag="P5537_14100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV79217.1"
                     /translation="MTPADTLRFATRAATAWPLRTALMMLAMSIGVAAVVVLTALGDG
                     ARRYVVNEFSALGASLLIVLPGRTETGGVNAGSFVSSTPRELTNADAAALLRLSLVQR
                     VAPLAVGNAEIAVGGRLREATVVGTSADFLELRGLEIGQGSFLPREDFNRASAVAVIG
                     DTLRSELFPGQGAVGRMIRVGDTRLRVIGVLAPSGRGLGMTTDELVLVPVATAQAMFD
                     TSGLFRIFVEARGREALPGAQRQVEERLRARRDGELDFTVITQDAVLGTFDRILGALT
                     LGVAGIAAISLAVAGILVMNVILVAVTQRTAEIGLLKALGARAGTIRAAFLAEAALLS
                     VAGALAGFALGHVGAWGVRLAFPELPAWPPDWAVVAALATALGTGVLFGVLPARRAAR
                     LDPVQALSRR"
     gene            8434..>9546
                     /locus_tag="P5537_14105"
     CDS             8434..>9546
                     /locus_tag="P5537_14105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV79218.1"
                     /translation="MRWQDSLHLALRALTAHRLRSFLTLLGIGVGIAAVILLTSIGEG
                     LHRFVLAEFGQFGTNVINLHPGRQGARGGPPGLPSTARDLTLDDAAALARLPNVRNVS
                     GSVSGNAEVRAQGRVRRSTVLGVGPQMQEVYSMRVGVGQFLPPDEAASARAFVVLGPK
                     LKHELFGSANALGERVEIGAERYRVVGIMEEKGQFLGIDLDDAAYIPVVRGMALYQRD
                     GLMEIALTYDPEAPAARVAEAVKRMMIARHGREDFTVLTQEDMLATLSNILDLLTAAV
                     GALGAISLLVGGVGIVTIMSIAVTERTGEIGLLVALGARRRTILALFLGEAVVLAGIG
                     GLLGLLAGAGLAQLVGLLVPAMPVATPWQYALAAEVV"
BASE COUNT         1514 a         3425 c         3279 g         1328 t
ORIGIN      
        1 atcgcatgtc ggttactcgg cttgcggaaa tcaaatgctt ctcaggctct gagccggcat
       61 cacggcttgc gggcagggcg gcgggcatcg aaccgctgct ttcgcgcctg ccggcgctcc
      121 tacatgaacc atcacgcact gcgcccacgt cgctgccggc gcgcgaaaca cccaccatgt
      181 catgaaccat cgcgcgcggc gcccatgttg gtgtcggtgc acgacacgcc cgcgatgcca
      241 tgaaccgtcg cgcggcgccc atgtaggagc gccggcaggc gcgaaggcgg cgttcgctcc
      301 ggggcgggga cgctcagcgg ctcgaggccg caagcatcgc gccggcgccg acgaagaggc
      361 cgccgaagat gcggttctgc aggcgcagca ggcgcgggtt gcgcagcagc gggcggaagc
      421 gggtggcgag cagcgcgtag caggacatca ccatcatgtc gaccgccacc atggtcgcgc
      481 cgatgatcgc gaactgcggc cactgcggcc ggtcgggcac gatgaactgc ggcaccagcg
      541 cggcgatgaa cacgatcgcc ttcgggttgg tcaggttgac caggatgccc tgggcgtaga
      601 gctggcgacg cgactgcacg cgctggccct cgccgtcgcc gccgatcggc tcgggcggcg
      661 agcgccattt ctgcacgccg agccagatca ggtaggccgc gccggcgaac ttcaccaccg
      721 cgaaggccgt ctccgaggtc gcgagtaccg cgccgaggcc gagcgccacc acgcccagtt
      781 gcaggagcag cgcgatctgc aggccggcga tcgcgcgcag cgcggcgccg tagccgtagc
      841 gcaggccggt cgacatcgac agcacggcgc ccggcccggg cgagaccgcg atcaccagcg
      901 cggcggcaag aaaggcgagc cacatcgtcc agctcatggg agcctccgcg aggcaggttc
      961 agcgagttcg ttcatcggcg gcgttcacgc aaagatgctg tgcagcatct ttgcgcacag
     1021 caggacgagc attccggcga acaccttctt cagcgtcgcc accggcaggc ggtgggcgag
     1081 cttcgcgccg agcggggcga agaaggtgct gaccagggag accagcacca gcgccggcag
     1141 gtacacgtag ccgaaggtga gcgccggcat gtcttgcgcc ccccagccat tgacgaggta
     1201 gccgacggtg ccggcgagcg cgatcggcag tccgatcgcc gccgaagtgc cgatcgcgtt
     1261 ctgcatcttg acgttgcacc aggtcatgaa gggcaccgac agcgagccgc cgccgatcgc
     1321 gaccagcgcc gagacgccgc cgatgcccag gccggccgcg ctcatgccga gcgcgccggg
     1381 cagctcgcgc gagggcttgg gcttgatgtt gagcagcatc tggatcgaca cgtaggccat
     1441 gaagacggcg aagaagatcg ccagcggcac ggtggacacg cgtgaggcga cgaaggtggc
     1501 ggcgaaggtg ccgaccagga tgccgggcgt gatcgcccgc accacgtccc agcgcacggc
     1561 gccgcgggcg tggtgggcgc gcaggctgga caccgaggtc agcacgatgg ctgccatcga
     1621 ggtgccgagc gccatgtgca ccacctggga ctgcgggaag ccctgggcca ggaagaaggt
     1681 cgtcagcatc ggcaccatga tgccgccgcc gcccacgccg agcaggccgg cgaagaagcc
     1741 caccgccgcg ccgagcaccg ggtaggcgag ccaccagagg tcgaaggtca ttgcgtttcc
     1801 gtttcgattg ggtgcgcgcc gcgtgctgcg gtgcgcaaag agcggaacta tcaggcatag
     1861 cccggatgcc gcgcaaggga gaacacgtcc gcggtgtcct gcagacacga cagggcgtgc
     1921 gcagacgagg catcgcagcg ctcgcgcggc cggcgccgcg cacggggcgg cccgccccgt
     1981 cccggggcgc cgagcccgcg cgcccgatcg gctacaatcg ggccatcacg ccgagcgcca
     2041 gcggccccgg ctgcgccttg tggcgaatcc tcatccttcc gccgatcctt ccgactcccg
     2101 ccttgccgat gaaacccgaa aagaaccccg ccactcctgc cgccgaagcc cccgtcgtct
     2161 ccaacttcat ccgcagcatc atcgacgagg acaaccgcaa cggcaaatgg ggcggccgcg
     2221 tcgagacgcg cttcccgccc gagcccaacg gctacctgca ctacggccac gccaagtcga
     2281 tctgcctgaa cttcggcctg gccgaggcct acggcggcgt ctgccacatg cgcttcgacg
     2341 acaccaaccc cgagaaggaa gagcaggaat acgtcgacgc catcctcgag gcggtgcatt
     2401 ggctcggctt cgagtggggc gagcacctgt acttcgcctc ggactatttc gaccgcatgc
     2461 acgactgcgc gatcagcctg atccaggccg gcaaggccta tgtggactcg cagtcggccg
     2521 aggagatgcg cgccaaccgc ggcacgctga ccgaggcggg caaggacagc ccctaccgca
     2581 atcgcagcgt ggccgagaat ctcgacctgt tcgcacgcat gcgcgccggc gaattcgccg
     2641 agggcacgca catcctgcgc gccaggatcg acatggcgag ccccaacatc aacctgcgcg
     2701 acccggcgat ctaccgcatc cgccacgcca cccaccatcg cacgggcgac gcgtggtgca
     2761 tctatccgat gtacaccttc gcccacccga tcgaggacgc gatcgagaac atcacccact
     2821 cggtgtgcac gctcgagttc gaggaccagc gcccgttcta cgactggctg ctcgacgcac
     2881 tcgccaccga gggccgcttc ccgcgcccgc tgccgcagca gatcgagttc gcccgcctca
     2941 acctgaccta cgtggtgctg tccaagcgca agctgatcca gctcgtgaac gaaggccatg
     3001 tcgacggctg ggacgacccg cgcctgccca cgctcgtcgg cgcccgccgc cgcggcttca
     3061 ccgccacggg cttccgccgc ttcgccgagc gcatcggcgt gtcgaaggcc gactcgtgga
     3121 tcgacatgag cgtgctcgaa gagtgcatgc gcgacgacct caacgaggcc gccgaacgcc
     3181 gcgtggcggt gctcgatccg ctcaagctcg tgctcaccaa ctacgccgag ggcgaatccg
     3241 agctgtgcca ggcgcccaac cacccgctca agcccgagct ggggaaacgc gacatgccgt
     3301 tctcccgcga gctgtggatc gagcgcgagg acttcatgga agagccggtc aagggtttcc
     3361 accgcctcta cccgggcaac atggtgcgcc tgcgctacgg cttcgtcgtc agatgcaccg
     3421 gctgcgagaa ggacgccgac ggcaccatca ccgccgtgct cgccgagtac atgcccgact
     3481 ccaagtccgg cacccccggc gccgacaact acaaggtcaa gggcaacctg cactgggtgt
     3541 ccgtggcgca cggctacgag gccgaggtcc gcatctacga ccgcctgttc gcccacccgc
     3601 accccggcca gcgccgcgag ggcgacgcgc cggacttcga acgtgacttc ctcaccgaca
     3661 tcaaccccga cagcaagcgc atcatcaccg cgtatctgga gccggcgctc aaggatgccc
     3721 ggccggagga gcacttccag ttcgaacgcc acggctactt cgtcgccgac cgcgtggact
     3781 cgcagcccgg cgcgccggtg ttcaaccgca cggtgacgct gaaggattcg tgggccaagg
     3841 gcgggaagta ggccctcgcc gacaggagcg caagcatggc tatcgcaacc cgaacgaccg
     3901 atccgatcgc agcctcgctc gcctgcctgc gctgccacct gccacccgga agccgcgtga
     3961 tcgtgttcgg ttcgcaagca cgcggggagg cccgcgacga cagcgacctc gacctgctgg
     4021 tcgtggagcc ggaggtccgc aaccgtttcg acgagatggc ccgcctcgcc tccctgctcg
     4081 gccgtgaatt gatcccggcc gacgtggtcg tgatgagcga tgaagcgttc gagcaggagc
     4141 gcgcccagcc gaacacactc gcctggcgcg ccgctcgcga aggacggatc catgcattcc
     4201 cccagtgaac tcgcgctcgg cctgctacac agggcacggg acgatggcta cgtggtcgac
     4261 cgcctggcgc aagatcccgc agcaccggac tgggtcatcg gattccatgc ccagcaggcg
     4321 gtagagaagg ctatcaaggc cgttctcgcg aatgcgaagg tcgttttccc gaggacgcac
     4381 aacatcgcga tgctgcttgc tctgctacaa cagaacggaa ttcaggctcc cgatcaggat
     4441 gtctttctcg agaggcttac ccccttcggg gttgccgccc gatacgacag agaactggat
     4501 caaagctttt ccctgaatcg agaacgcacc cgattggaga tccttgcgct gctggattgg
     4561 gctgaagcga tgttgagcaa cgcgaaaaat ggctcggcgg gatctccatg acggtaccca
     4621 agtatcacga gctgattcgt ccgctgctcg atctcgtcgc tgatggacgc ccccgcaacc
     4681 tgcgagaagc tgcgcaggag cttgcggagc ggctgtccct cacggacgag gacttgaccg
     4741 aaactctgcc gagcggctat ccgcgatatc tcaatcgtgt cggttgggcg aaaagcgatc
     4801 taaacaagac cggtctcatt gagagttgtg ggcgcggcct cttccggatc tctgagaggg
     4861 gcagtaacgc gcttcctgaa cttccgcctc aactcgatcg gaaatacttc gaggcgcgcg
     4921 aactgggaag ctggaagagt gtttcggctc cccccacatc gagcgcagga tcaagctcga
     4981 ccgcatctac ctgcaggcga agcgctgggc ggatgcgccc gtgggcggcc cggacatcga
     5041 cggattcctc ggcgcactcg caaagcatgg agccaaccgc ggcgttttcg tcaccaccag
     5101 tcgattcacg caagacgcaa ggcgtgcggt cgaactgccc caccttcggc tcgtcctgat
     5161 cgatggcgaa gagctcgccc ggctcgcggt cgaacacaac gtcggcgtgt cggtgaagcg
     5221 caaaatcgaa ttgaagcgcc tcgacaccga cttcttcgac gacctctgaa cgccccctcc
     5281 atgaagacct tgcgccccat cctcctgctc gccctcctcg ccgcgctggc gggcgcgggg
     5341 gggtggtggc tgacccgccc gacgccggtc gaggtggtgg tgcatgaggt ggcccgcggt
     5401 acggtcgagg ccacgctgac caacacccgc gccggcgagg tcgaggcctg ccagcgcgcg
     5461 aagatggcga ccatcgccgg cgggcgcatc gagtggctgg gcgtggagga aggcgaccgc
     5521 gtcgaggccg ggcaggtgct gatgcgactg tggcatggcg acctcgacgc gcgcgctgcg
     5581 gtcgcccgcg cccagctcgc caccacgcgc cagcgcgtgc acgaagcctg caccgtggcg
     5641 gccaacgccg agcgcgaggc cgcgcgccag gcgcagctga tgcgccgcgg cttcgtctcc
     5701 gccagcgccg aggagaaggc gcgcaccgag gcgcgcgcgc gccgcgccgc ctgcgacacc
     5761 gcgcaggccg acgtcgccac cgccgcagcc cagctcaccg ccaccgagac cgagcgccag
     5821 cgcctggtgc tggtcgcgcc cttcgcgggc accgtggcca agatcagcgg cgagctcggc
     5881 gagtacgcga cgccctcccc gcccggcgtg ccgatgccgc cggcgatcga cctgatcgac
     5941 gactcctgcc tgtacgtgaa ggcgccgatg gacgagatcg acgcgcccaa gatccagccc
     6001 ggcctgccgg tgcgcatcac gctcgaggcc attcccggca aggtgttcgc cggtacggtg
     6061 cggcgcgtgg cgccctacat caccgcggtc gagaagcagg cgcgcacggt ggcggtggat
     6121 gtggacttcg tccgtcccga cgaggcgcgc gggatgctgg tgggctacag cacggacgtg
     6181 gagatcgtgc tggcgacccg tgcggaggta ctgcggattc ccaccggcgc cttgcgggaa
     6241 ggcggcaagg tgctggtggt ggagggcgac acgctggtcg agcggacgct gcagaccggg
     6301 gtggcgaact gggagttcac cgaggtggtg tcggggctgg acgcaggcga gcggatcgtg
     6361 acctcgctgg agcgcgaggg ggtggtagcc ggggcgaagg tgctggctcg acccgcgcag
     6421 gcgcgctgag ccgcacccgg tcgcccgcat ccatcgacga cgcgcaacga ggacttgctt
     6481 caagcccggc catggcccag atcgaactcg agcacatcga ccgcatcttc aagctcggcg
     6541 acagcgaggt gcacgcgctg cgcgacatca cgctgcgcat cgaggccggc gagtacgtcg
     6601 cggtcatggg accgtccggc tcgggcaaat cgaccctgct caacctcctc ggcctgctcg
     6661 accgccccaa cgccggcgcc taccggctcg aaggccgcga cgtcaccacg ctctcggccg
     6721 acgagcaggc cgcggtgcgc agcgcccgca tcggcttcgt gttccagagc ttccacctcg
     6781 tccctcgtct cagcgcggct gagaacatcg gcctgccgct ggtgctcgcc ggcgtccccg
     6841 cggccgagcg cgcgccgcgc gtcgcccggg ccctgcagga cttcggcctc gagggccgtg
     6901 cccgccaccg ccccgacgag ctctccggcg gccagcgcca gcgcgtcgcg atcgcacgcg
     6961 ccaccatcat gcggccggcg atgctgctcg ccgacgaacc caccggcaac ctcgaccgcg
     7021 ccaccggcca cgaggtcacc gcgctgctcg aggcgctcaa cgccgccggc accacgctga
     7081 tcgtcgtcac ccacgacccc gcgatgggcg agcgcgcgcg ccgccgcatc ctgatggagg
     7141 acggcgcgat ccggcaggaa ctgcaggccg cggcggcagc gcccgaggcc cctggctccg
     7201 gttccaccgc cccgccgcca tgaccccggc cgacaccctg cgcttcgcca cccgcgccgc
     7261 caccgcctgg ccgctgcgca ctgcgctgat gatgctggcg atgtcgatcg gcgtggccgc
     7321 ggtggtggtg ctcaccgcgc tcggcgacgg cgcccggcgc tacgtggtga atgagttctc
     7381 cgcgctcggc gccagcctgc tgatcgtgct gcccggacgc accgagaccg gcggcgtcaa
     7441 tgccggcagc ttcgtcagca gcacgccgcg cgagctcacc aacgccgacg ccgccgcgct
     7501 gctgcggctg tcgctggtgc agcgcgtggc accgctcgcc gtgggcaacg ccgagatcgc
     7561 cgtcggcggg cggctgcgcg aggccacggt ggtcggcacc agcgccgatt tcctggagct
     7621 gcgcgggctc gagatcggcc agggcagctt cctgccgcgc gaggacttca accgcgcctc
     7681 ggcggtggcg gtgatcggcg acacactgcg cagcgagctc ttccccgggc agggcgcggt
     7741 gggccgcatg atccgcgtcg gcgacacgcg gctacgcgtg atcggcgtac tcgcaccgtc
     7801 cgggcgcggg ctgggcatga ccaccgacga gctggtgctg gtgccggtgg cgaccgcgca
     7861 ggcgatgttc gacaccagcg ggctgttccg catcttcgtc gaggcgcgcg ggcgcgaggc
     7921 cctgcccggc gcgcagcgcc aggtcgagga gcgcctgcgc gcgcgccgcg acggcgagct
     7981 cgacttcacc gtgatcaccc aggacgccgt gctcggcacc ttcgaccgca tcctcggcgc
     8041 gctcactctg ggcgtggccg gcatcgccgc gatcagcctg gcggtcgccg ggatcctggt
     8101 catgaacgtg atactggtcg cggtcaccca gcgcaccgcc gagatcggcc tgctgaaggc
     8161 gctcggcgcg cgcgccggca ccatccgcgc cgccttcctc gccgaggccg cgctgctctc
     8221 cgtcgccggc gcgctcgccg gcttcgcgct cggccacgtc ggcgcctggg gcgtgcgcct
     8281 ggcctttccc gagctgccgg cgtggccgcc cgactgggcg gtggtcgccg cgctcgccac
     8341 cgcgctcggc accggggtgc tgttcggcgt gctgcccgcg cgccgcgccg cccggctcga
     8401 cccggtgcag gccttgtcga ggcggtagcg gcgatgcgct ggcaggacag cctccacctc
     8461 gccctgcgcg cgctcaccgc gcatcggctg cgcagcttcc tgaccctgct cggcatcggc
     8521 gtgggcatcg ccgcggtgat cctgctcacc tcgatcggcg agggcctgca ccgcttcgtg
     8581 ctcgccgagt tcggccagtt cggcaccaac gtgatcaacc tccacccggg ccgccagggc
     8641 gcgcgcggcg gcccgcccgg cctgccctcg accgcgcgcg acctcaccct ggacgacgcc
     8701 gccgcgctcg cccgcctgcc caatgtgcgg aacgtctcgg gctcggtgag cggcaacgcc
     8761 gaggtgcgcg cgcagggccg ggtgcggcgt agcacggtgc tcggcgtggg gccgcagatg
     8821 caggaggtgt actcgatgcg ggtgggtgtg gggcagttcc tgccgcccga cgaggcggcg
     8881 agcgcgcgcg ccttcgtggt gctcggaccg aagctcaagc acgagctctt cggcagcgcc
     8941 aacgcgctcg gcgagcgcgt cgagatcggc gccgagcgct accgcgtggt cggcatcatg
     9001 gaggagaagg gacagttcct cggcatcgac ctcgacgacg ccgcctacat cccggtggtg
     9061 cgcggcatgg cgctgtacca gcgcgacgga ctcatggaga tcgcgctcac ctacgacccc
     9121 gaggcccccg ccgcgcgcgt ggcggaggcg gtgaagagaa tgatgatcgc gcgccacggg
     9181 cgcgaggact tcaccgtgct gacccaggag gacatgctgg cgacgctgtc gaacatcctc
     9241 gacctgctca ccgcggcggt gggcgcgctc ggggcgatct cgctgctggt gggcggggtg
     9301 ggcatcgtca ccatcatgag catcgcggtc accgagcgca ccggcgagat cggcctgctg
     9361 gtggcgctgg gcgcgcgccg gcgcaccatc ctcgcgctct tcctcggcga ggcggtggtg
     9421 ctggcgggca tcggcgggct gctcggcctg ctcgcgggcg cgggcctggc gcagctggtc
     9481 gggttgctgg tgccggcgat gccggtcgcg acgccctggc agtatgcgct cgcggcggag
     9541 gtggtc
//
LOCUS       DAOTIN010000123         9409 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_8699_length_9409_cov_8.710391, whole genome shotgun sequence.
ACCESSION   DAOTIN010000123 DAOTIN010000000
VERSION     DAOTIN010000123.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 9409)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 9409)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9409
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_8699_length_9409_cov_8.710391"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..536)
                     /locus_tag="P5537_14110"
     CDS             complement(<1..536)
                     /locus_tag="P5537_14110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase N-terminal
                     domain-containing protein"
                     /protein_id="HRV79219.1"
                     /translation="MPTSLRRKLLSSLAAPTGLLLAIAGAVAYGTAKGMVGDAYDHNL
                     LNLAHAIATHVHPQADGLSLSLSSEVEAVLRSDTQDRIYFRVRDLGGRLLGGDAALPL
                     LDDSDAASALPVPYSPVGRDTPQPSRPPSTRPLYRDLVHAGEPIRALRLYRELPAGGY
                     YVTVAETLVKREAAMDRLL"
     gene            complement(514..1191)
                     /locus_tag="P5537_14115"
     CDS             complement(514..1191)
                     /locus_tag="P5537_14115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HRV79220.1"
                     /translation="MRLLLVEDDPALAEGIAEFLRGQGDEVEVEDDGMRADRRLQDDG
                     YDFVLLDVGLPGLGGYELVRRIRKRGQRMPVIVITARDALDDRIYGLDLGADDYLVKP
                     FELAELSARMRAVQRRGGGAGARLAFGALVLDLDGRLAELDGAPMALSGREWEVLEAL
                     VRADGRTVTRENLQGDGSGNALEVCISRLRPRMEAAGLLIRTVRGFGYRLERSKERRE
                     GADQPPA"
     gene            1375..2637
                     /locus_tag="P5537_14120"
     CDS             1375..2637
                     /locus_tag="P5537_14120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HRV79221.1"
                     /translation="MSDLLPLDAEQIEAFLIATGIGLLIGLERERVPSARAGLRTFGL
                     VGMLGALVAMLGEQLGSPAPFVAGLVLVGLTIIAAYLRHPDPSDPGTTSVAALVLCYC
                     LGAASWLGHAQVAVMLAVATTVLLYFKAQLRGMATRLEARDWISILQFGVLSLVILPM
                     LPDEEMGPYGALNPRQIWWMVVLIAGVGLAGYTALQVAGVRYGAAFVGVFGGLASSTA
                     TTLLYARQARALPAAGAMAALVIVIANLVMVLRVGVIAALVAPGVAATLLRVIVPALA
                     LGALGALWLWRQLAERAETVLPTTGNPTELKTALGFGAAYALVLLAAAWLSDFAGNRG
                     LYVLAFVSGLTDVDAITLSSLRLYALERLELVATVTAVGIAMLANLAFKLGLAAAIGG
                     RALALRAAAGMASVALGLLAGLAWVGLG"
     gene            complement(2672..2839)
                     /locus_tag="P5537_14125"
     CDS             complement(2672..2839)
                     /locus_tag="P5537_14125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79222.1"
                     /translation="MDKERLFRTGFAIFWLVALGLLVLDTASSSNIRVEPPPIALGSG
                     QAASGGHCSGR"
     gene            complement(2850..4022)
                     /locus_tag="P5537_14130"
     CDS             complement(2850..4022)
                     /locus_tag="P5537_14130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeeE/YedE family protein"
                     /protein_id="HRV79223.1"
                     /translation="MRWFSRFLLVFGALAGVLAVTLAAGLRQGLLALLGIGFGAVLQG
                     ARFGFTTGWRDLIERRDPQGLWAQMLLMVLAAALTLPLLAGSGGELVGAVAPLTISLV
                     LGAFLFGAAMQLADGCGSGTLYKAGGGSPLSFVVLPTFAFGSFLGASHQPAWIELGGL
                     PAVDLLAFGWPTALALTVAACGLVAWLAGRARGNTEGQAQASPQAVTQQLVRTGTASF
                     VAAARPAQPRWATRWWLGALLLAVLYLAHLVVAGQPWGIVYGMGVWGAKAVSALGWDL
                     SGDAFWGIAPHAQRLVEPILADVTSVTNIGLIYGAIAASRWNGAPKLSMPSGRRLAAA
                     AVAGLVMGYSARMAFGCNVGAYLGGIASASLHGWVWFALAFAGSIVGVRIRRRVGA"
     gene            complement(4036..5031)
                     /locus_tag="P5537_14135"
     CDS             complement(4036..5031)
                     /locus_tag="P5537_14135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HRV79224.1"
                     /translation="MLKKLAPLPLAIALVASLGLAAPAFASTAEHAPAAPSAQAAAPA
                     PLLQAAELKALIGQPGVRVLDIRADKDYAAGHVPGAVNTPYGKYRGPKENPGQLPSEA
                     ALTQLLQAAGVDRDTHVVVVHAGSDHTDFGAAARVYWTLKVGGLTRLSILDGGTKAWQ
                     AAGGALETAAPQVTPSQFSYRYDQEQVVTSEELAATVKAGNAPLLVDARPPRFFAGET
                     RTDAAARYGTLPGAKSFDNAQFFPQGGTTLKPASELKALVAQSGAAAAPAVSFCNTGH
                     WAATNWFVMSEIAGNKSVKLYPSSVVEWSQSDLPMDNQPSRLSALMQDAKRALDK"
     gene            5261..6052
                     /locus_tag="P5537_14140"
     CDS             5261..6052
                     /locus_tag="P5537_14140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3750 domain-containing protein"
                     /protein_id="HRV79225.1"
                     /translation="MNHLSISLRILAVLLLLSVGLSLANDPRPTVAGGQGGWRGAPRH
                     SAGIAPDPARFADTAIVQVYAAATYGWRGYFAVHPWIIYKRAGETAYTRYDVIGWGRG
                     NVVRRNHALPDGLWFGAMPRVLVEHRGEGVEAMIGQIEAAVASYPYADTYRSYPGPNS
                     NTFLAHIGREVPSLRLDLPANAIGKDYRPLERPVGLSPSGSGLQVSLLGLLGLSLGVE
                     EGIELNVLGLNFGLDLNRPGLRLPAIGRLGFDDALVSERNAASVP"
     gene            complement(6131..7048)
                     /locus_tag="P5537_14145"
     CDS             complement(6131..7048)
                     /locus_tag="P5537_14145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HRV79226.1"
                     /translation="MSHSPQPARWLPFVVLGIGLAAISFGAIFARLAQAEGVSSLAVA
                     TWRLGFAALIITPVALLQSRHELARLTRRQIGMALAAGFFLALHFATWISSLEYTSVA
                     SSTALVTTNPLWIGLASFLIFRETPTKMMIGGIALSFAGSLFIFWSDSQSASAGSNPM
                     LGNLLALIGSWCFSAYLLIGRRLRAGLGLPAYIWLAYGAAALFLFAASGAGGVELFTL
                     SKTAWLVLLAMALGPQLLGHTAYNWSLRYVSATFVAVVTLGEPVGSALLAFLIFGEGF
                     APLQFVGFSLLLVGIYLAAKGERGAGNAS"
     gene            complement(7420..8133)
                     /locus_tag="P5537_14150"
     CDS             complement(7420..8133)
                     /locus_tag="P5537_14150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV79227.1"
                     /translation="MLKMEGVHAHYGHIHALRGIDVEVQVGEIVTLIGANGAGKSTLM
                     MSLFGNPKASAGRIVFDGEDITRVHTHEIARRGIALVPEGRRIFPRMTVTENLQMGTA
                     HADPANYAADTARVFAMFPILEERQTQRAGTLSGGEQQMLAIGRALMSRPKLLLLDEP
                     SLGLAPIYIRKIFQIVRELNRDHGMTILLVEQNANQALRVADRGYVLQHGEITLAGTG
                     AELLASPEVRAAYLEGGHA"
     gene            complement(8133..8972)
                     /locus_tag="P5537_14155"
     CDS             complement(8133..8972)
                     /locus_tag="P5537_14155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HRV79228.1"
                     /translation="MNTPATLLSVRNLTMRFGGLTAIDDLSLEVPAGRITGIIGPNGA
                     GKTTLFNCLTGFYKPTTGTLRLAHPRRGEMRLEALPSHRVARDAQVVRTFQNIRLFPK
                     MTVLENLIVAQHNVLQRASKFSIAGLFKLPGYREAERQAIERAAMWLARLKLTHLADD
                     AAGDLPYGIQRRIEIARALCVDPVLLCLDEPAAGLNPRESAELNELLLYLCGELGIAI
                     LLIEHDMSVVMNVSDHIGVISYGRKIAEGTPAQVKHDPQVIKAYLGEDEDEEEEVKGG
                     AAA"
     gene            complement(8969..>9409)
                     /locus_tag="P5537_14160"
     CDS             complement(8969..>9409)
                     /locus_tag="P5537_14160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HRV79229.1"
                     /translation="KLPVGRAWEALREDEIACQAMGMNTTNIKLSAFAIGAMLGGFAG
                     VFFAARQGFISPESFVFTESAIILAIVVLGGMGSQMGVVLAATLLVLIPEFGRNFAEY
                     RMLLFGLAMVLIMVWRPGGLLAHREPTVRLNALDKTAATQEAAR"
BASE COUNT         1316 a         3185 c         3505 g         1403 t
ORIGIN      
        1 agcaggcggt ccatcgccgc ctcgcgcttg accagggtct cggcgacggt gacgtagtag
       61 ccgccggcgg gcagctcgcg atacaggcgc aaggcgcgga tcggttcgcc cgcatgcacg
      121 aggtcgcggt acagcggccg cgtggagggc gggcgcgacg gctgcggcgt gtcgcggccg
      181 accggggagt agggcaccgg caaggcggac gccgcatcgc tgtcgtcgag cagcggcagg
      241 gccgcgtcgc cgccgagcag gcgtccgccg aggtcgcgca cgcggaagta gatgcgatcc
      301 tgggtgtcgc tgcgcagcac cgcctcgacc tcggacgaca ggctcaggct gagcccgtcg
      361 gcttgcgggt gcacgtgggt ggcgatcgcg tgggcgaggt tgagcaggtt gtggtcgtag
      421 gcgtcgccga ccatgccctt ggcggtgccg taggcgaccg cgccggcgat cgcgagcagc
      481 aggccggtgg gtgccgcgag gctgctgagg agcttacgcc ggaggctggt cggcaccttc
      541 gcggcgctcc ttgctgcgtt cgagccggta gccgaagccg cgcacggtgc ggatcagcag
      601 cccggcggcc tccatgcgcg ggcgcaggcg cgagatgcac acctcgagcg cgttgccgct
      661 gccgtcgccc tgcagattct cgcgcgtgac cgtgcggccg tcggcgcgca caagcgcctc
      721 cagcacctcc cactcgcgtc cgctcagcgc catcggcgcg ccgtcgagct cggccaggcg
      781 gccgtcgaga tcgaggacca gcgcgccgaa ggccagccgc gcgccggcgc cgccgccacg
      841 gcgctgcacc gcgcgcatgc gcgcgctcag ctcggcgagc tcgaagggct tcaccaggta
      901 atcgtcggcg ccgaggtcga ggccgtagat gcggtcgtcg agcgcgtcgc gcgcggtgat
      961 cacgatcacc ggcatgcgct ggccacgctt gcggatgcgg cgcaccagct cgtagccgcc
     1021 gaggccgggc aggccgacgt cgagcaggac gaagtcgtag ccgtcgtcct gcagtcggcg
     1081 gtcggcgcgc atgccgtcgt cttccacctc gacctcgtcg ccctggccgc gcaggaactc
     1141 ggcgatgccc tccgcgagcg cggggtcgtc ctcgaccagc aaaagtctca tctgtcttcc
     1201 tccatggcgg accctgcggg cggaccccct gtccgccacg gcgccggatg cgaccggcgg
     1261 gtcctgcggc tcgaatcgta tcccggtgcg agcgcgcttg catcgccgcg cacgccgcgg
     1321 cgtatgatcc cactgtcgat cgccctctgc cgggcctgcg cccggcccgc cgccatgtcg
     1381 gacctgctgc cgctcgatgc cgaacagatc gaagccttcc tgatcgcgac cggaatcggc
     1441 ctgctgatcg ggctggagcg cgagcgcgtg ccctcggcgc gcgccggcct gcgcaccttc
     1501 ggcctggtcg gcatgctcgg cgcgctggtg gccatgctcg gcgaacagct cggcagcccc
     1561 gcacccttcg tcgccggcct ggtgctggtc ggcctcacca tcatcgccgc gtatctgcgc
     1621 caccccgatc cgtccgatcc cggcaccacc tcggtggcag cgctggtgct gtgctactgc
     1681 ctgggggcgg cgagctggct gggccatgcg caggtcgcgg tcatgctcgc ggtggcgacc
     1741 accgtgctgc tctacttcaa ggcccagttg cgcggcatgg cgacgcggct ggaggcgcgc
     1801 gactggatct ccatcctgca gttcggcgtg ctctcgctgg tcatcctgcc gatgctgccg
     1861 gacgaggaga tgggcccgta cggcgcgctc aacccgcgcc agatctggtg gatggtggtg
     1921 ctgatcgccg gggtcgggct tgccggctac actgcgctgc aggtcgccgg ggtgcgctat
     1981 ggcgcagcct tcgtcggcgt cttcggcggc ctggcctcga gcaccgcgac cacgctgctg
     2041 tatgcccgcc aggcgcgcgc gctgcccgcg gcgggcgcga tggccgcgct ggtgatcgtg
     2101 atcgccaatc tggtgatggt gctgcgggtg ggggtgatcg ccgccttggt cgcgcccggg
     2161 gtcgccgcga ccttgctgcg cgtgatcgtg ccggccctgg cgctcggcgc gctgggtgcg
     2221 ctgtggctat ggcgccagct cgcggagcgc gccgagacgg tgctgccgac caccggcaac
     2281 ccgaccgagc tcaagaccgc gctcggcttc ggcgcggcct acgcgctggt gctgctggcc
     2341 gcggcgtggc tgtccgactt cgccggcaac cgcggcctgt acgtgcttgc cttcgtgtcc
     2401 gggctcaccg acgtcgacgc gatcacgctg tccagcctgc gcctgtacgc gctcgaacgt
     2461 ctcgagctgg tcgccacggt caccgcggtc ggcatcgcca tgctcgccaa cctcgccttc
     2521 aagctcggcc tcgccgcggc gatcggcggc cgcgccctcg cgctgcgcgc cgccgccggc
     2581 atggccagcg tcgcgctcgg cctgctcgcc ggcctggcct gggtgggact cggctagtcc
     2641 gcgaatgact ttcgcccctg acgcctcacg cctaacgccc cgaacaatgc ccccccgagg
     2701 ccgcctggcc gctgccgagc gcgatcggcg gcggctccac gcggatgttg ctgctgctcg
     2761 cggtgtcgag caccagcagg ccgagggcga ccagccagaa gatggcgaag ccggtgcgga
     2821 agagtctttc cttgtccatg tcttcctcct cacgccccga cgcggcggcg gatgcgcacg
     2881 ccaacgatgg agccggcgaa cgcgagcgcg aaccacaccc agccatgcag actggccgag
     2941 gcgatgccgc ccaggtaggc gccgacgttg cagccgaagg ccatgcgcgc gctgtagccc
     3001 atcaccagcc cggccaccgc tgcggccgcc agccgacgcc ccgagggcat gctgagcttt
     3061 ggtgcgccgt tccagcgcga ggcggcgatc gcgccgtaga tcaggccgat gttggtcacc
     3121 gaggtgacgt cggcgaggat gggctcgacc aggcgctgcg catgcggcgc gatgccccag
     3181 aaggcgtccc cggagagatc ccagccgagc gcggagaccg ccttcgcgcc ccacacgccc
     3241 atgccgtaca cgatgcccca gggctggccg gcgacgacca ggtgggccag gtagagcacg
     3301 gccagcagca gcgcgccgag ccaccagcgc gtggcccagc gcggctgcgc gggcctggcg
     3361 gcggcgacga agctggcggt gccggtgcgt accagctgct gcgtgaccgc ctgcggcgag
     3421 gcttgcgctt ggccttccgt gttgcccctg gcgcgtccgg ccagccaggc caccaggccg
     3481 caggcggcca cggtgagcgc gagcgcggtc ggccagccga aggcgagcag gtccaccgcc
     3541 ggcaggccgc cgagctcgat ccaggcgggc tggtgcgaag cgccgaggaa gctgccgaag
     3601 gcgaaggtgg gcagcaccac gaaggacagc ggcgagccgc cgccggcctt gtacaacgtg
     3661 cccgagccgc agccgtcggc gagctgcatc gcggcgccga acaggaaggc gccgagcacc
     3721 aggctgatcg tcagcggcgc caccgcgccg accagctcgc caccgctgcc ggcgagcagc
     3781 ggcagggtca gcgctgcggc gagcaccatc agcagcatct gcgcccacag cccctgcggg
     3841 tcgcggcgct cgatgaggtc gcgccagccg gtggtgaagc cgaagcgcgc gccctgcagc
     3901 acggcgccga agccgatgcc gagcagtgcg agcagcccct ggcgcagacc ggccgccagc
     3961 gtcaccgcga gcacgcccgc gagtgcgccg aagaccagca ggaaacggga gaaccagcgc
     4021 atcttcgcgt ccgccttact tgtcgagcgc gcgcttggcg tcctgcatca gcgcgctcag
     4081 gcgcgaaggc tggttgtcca tcggcaggtc ggactggctc cactccacga ccgaggacgg
     4141 atacagcttg accgacttgt tgccggcgat ctccgacatc acgaaccagt tggtcgctgc
     4201 ccagtggccg gtgttgcaga aggacactgc gggcgctgcg gcggcgccgg actgcgcgac
     4261 cagggccttg agctcgctcg ccggcttgag cgtggtgcca ccctgcggga agaactgcgc
     4321 gttgtcgaag gacttggcgc ccggcagcgt gccgtagcgc gcggcggcgt cggtgcgcgt
     4381 ctcgccggcg aagaacctgg gcgggcgggc gtcgaccagc agcggagcgt tgccggcctt
     4441 gaccgtggcg gcgagctcct cgctggtgac cacctgctcc tggtcgtagc ggtagctgaa
     4501 ctggctgggc gtgacctgcg gcgccgcggt ctcgagcgcg ccgccggcgg cctgccaggc
     4561 cttggtgccg ccgtcgagga tggacaggcg ggtgaggccg ccgaccttga gcgtccagta
     4621 cacgcgcgcc gcggcgccga agtcggtgtg gtcgctgccg gcatgcacca cgaccacgtg
     4681 ggtgtcgcgg tcgacgccgg cggcctgcag gagctgggtc agcgcggctt cggagggcag
     4741 ctggccggga ttctccttcg gcccgcggta cttgccgtag ggggtgttca ccgcgccggg
     4801 cacgtggccg gcggcgtagt ccttgtcggc gcggatgtcg agcacgcgca cgccgggctg
     4861 gccgatcagg gccttgagtt cggcggcctg cagcagcgga gcgggtgcgg cggcctgcgc
     4921 cgagggggct gcgggggcat gttcggcggt gctggcgaag gccggcgcgg cgaggccgag
     4981 gctggcgaca agggcgatgg ccaggggcag gggggcgagt ttcttcagca tgatcgtgtc
     5041 gtccgtcgta tgcgtttgct ggggggtggt gcgccggact gcgcggcgct gccatgacgc
     5101 gctgcagaat acgggaaagc tgaaatactc agaaggtctg tcggagaaaa tgtttataac
     5161 tttgaagaat taaataggcg ggcgtgtcgg catagaactc catgcgcgag cgatgatcac
     5221 aaggaagtgg ggccctccgg ccccggaaca gggaacccgc ttgaaccatc tctcgatcag
     5281 cttgcgcatc cttgccgtcc tgctgctgct ttcggtaggg ctcagcctcg ccaacgatcc
     5341 ccgcccgacg gttgctggcg ggcagggcgg ctggcgtggt gcaccgcgcc actccgcagg
     5401 gatcgcaccc gacccggcgc gcttcgcgga cacggcgatc gtgcaggtgt atgccgcggc
     5461 cacctatggc tggcgcggct actttgcggt gcatccgtgg atcatctaca agcgtgccgg
     5521 cgagaccgcc tacacgcgct acgacgtgat cggctggggg cgtggcaacg tggtgcggcg
     5581 caaccacgcg ttgcctgacg ggctgtggtt cggggccatg ccgcgcgtgc tggtggagca
     5641 tcgtggcgag ggcgtggagg cgatgatcgg gcagatcgag gccgcggtgg cgagctaccc
     5701 ctatgcggat acgtaccgca gctacccggg cccgaacagc aacaccttcc tcgcccacat
     5761 cggccgcgag gtgccgtcgc tacggctgga tctgccggcg aacgcgatcg ggaaggacta
     5821 ccgtccgctc gagcgcccgg tcggcctgtc gccttcgggg tcgggcttgc aggtctcgct
     5881 gctcggcctg ctgggcctga gcctgggggt ggaggagggc atcgagctga atgtcctcgg
     5941 cctcaatttc ggcctcgatc tcaatcgccc gggactgcgc ctgcccgcga tcggccgact
     6001 cggcttcgat gatgcgctgg tgtccgagcg caacgctgcc agcgtgcctt gatgccgcca
     6061 aggcgatcgc gaagcgtcgg atgcgctcct gcctttgccg cgtcctgctc gggtgcgtgc
     6121 ccccgcggcc tcacgacgcg ttgccggccc ccctctcgcc cttcgccgcc aggtagatgc
     6181 ccaccagcag caggctgaag ccgacgaact gcagcggcgc gaagccctca ccgaagatga
     6241 ggaaggccag cagggcgctg ccgaccggct cgccgagcgt gaccaccgcg acgaacgtgg
     6301 ccgacacgta gcgcagcgac cagttgtagg cagtgtggcc gagcagctgc ggaccgagcg
     6361 ccatcgccag caataccagc caggcggtct tcgacagcgt gaacagctcc acgccacccg
     6421 cgccgctggc cgcgaacagg aacagcgcgg cggcgccgta ggcgagccag atgtaggccg
     6481 gcagacccag cccggcgcgc aggcggcgac cgatcagcag gtaggcggag aagcaccagc
     6541 tgccgatcag cgccagcagg ttgccgagca tgggattgct gccggcgctg gcgctctggc
     6601 tgtcgctcca gaagatgaac aggctgccgg cgaaggacag cgcgatgccg ccgatcatca
     6661 tcttcgtcgg cgtctcgcgg aagatcagga aggaggccag gccgatccac agcgggttgg
     6721 tggtgacgag cgcggtgctc gaggcgaccg aggtgtattc gagcgagctg atccaggtgg
     6781 cgaaatgcag cgcgaggaag aagccggcgg cgagcgccat gccgatctgc cggcgggtga
     6841 ggcgggcgag ctcgtggcgc gactgcagga gggcgaccgg ggtgatgatc agcgcggcga
     6901 agccgagccg ccaggtggcg accgcgagcg aactgacgcc ttcggcctgg gcgaggcggg
     6961 cgaagatggc gccgaaggag atcgcggcga gaccgatgcc gaggacgacg aaggggagcc
     7021 agcgggcggg ttggggggag tgggacatcg ggaggtgggt gagatgacgg gtgaatgaga
     7081 agcgggcggt cagaggatag cgtggggctt cgagtcggtc gggcgcctgg ggttgaagga
     7141 ggcgcggctt cgatcggtcg ggcgcgtggg ggtgagggat gtgcggctac ggttcggccg
     7201 ggcggcgagg cgggtggcgc cgcctgcatt cgcggcctgc ggctgccctc ggcgaaaggc
     7261 ggcgcggggg cggcgacgca aactcggcgc tgcgcgcctc ggacatgcgt cgccttgttt
     7321 cccccgcgcc gcctttcgcc tcggcgctca tgaagttggc gccacccgcc tcgccgcccg
     7381 gccttgcgca gggggcgttt ggctgccgat tatcgcctct taggcgtggc cgccctccag
     7441 gtaggcggcg cgtacctcgg gactggccag cagttcggcg ccggtgccgg cgagggtgat
     7501 ctcgccgtgc tgcagcacat agccgcggtc ggccacgcgc agggcctggt tggcgttctg
     7561 ctcgacgagc aggatggtca tgccgtggtc gcggttgagc tccctgacga tctggaagat
     7621 cttgcggatg tagatcggcg ccaggccgag cgagggctcg tcgagcagca gcagcttggg
     7681 gcggctcatc agcgcgcggc cgatcgccag catctgctgc tcgccgcccg acagcgtacc
     7741 ggcgcgctgg gtctggcgtt cctcgaggat cgggaacatc gcgaacacgc gcgcggtgtc
     7801 ggcggcgtag ttggcggggt cggcgtgggc ggtgcccatc tgcaggttct cggtcaccgt
     7861 catgcgcggg aagatgcgcc ggccttcggg caccagggcg atgccgcggc gggcgatctc
     7921 gtgcgtgtgc acgcgggtga tgtcctcgcc gtcgaagacg atgcgcccgg cgctggcctt
     7981 ggggttgccg aacaggctca tcatcagcgt cgacttgccg gcgccgttgg cgccgatcag
     8041 ggtgacgatc tcgccgacct ggacctcgac gtcgatgccg cgcagcgcgt ggatgtggcc
     8101 gtaatgggcg tggacgccct ccatcttgag catcatgccg cggcccctcc cttcacttct
     8161 tcttcctcgt cctcgtcctc gcccaggtag gccttgatca cctgcgggtc gtgcttgacc
     8221 tgcgccggcg tgccctcggc gatcttgcgc ccgtagctga tcacgccgat gtggtcggac
     8281 acgttcatca ccacgctcat gtcgtgctcg atcagcagga tggcgatgcc gagctcgccg
     8341 cacaggtaga gcagcagctc gttcaactcc gccgactcgc gcgggttgag gccggcggcg
     8401 ggctcgtcca ggcacagcag cacggggtcg acgcacagcg cgcgtgcgat ttcgatgcgg
     8461 cgctggatgc cgtagggcag gtcgccggcg gcgtcgtcgg cgaggtgggt gagcttgagg
     8521 cgcgctagcc acatcgccgc gcgctcgatc gcctgccgct ccgcctcgcg gtagccgggc
     8581 agcttgaaga ggccggcgat ggagaacttg gacgcgcgct gcagcacgtt gtgctgggcg
     8641 acgatcaggt tctccagcac cgtcatcttt gggaacaggc ggatgttctg gaaggtgcgc
     8701 accacctggg cgtcgcgcgc gacgcggtgg ctgggcagcg cctccaggcg catctcgccg
     8761 cggcgcgggt gagccaggcg cagcgtgccg gtggtcggct tgtagaagcc ggtcaggcag
     8821 ttgaacagcg tggtcttgcc ggcgccgttg gggccgatga tgccggtgat cctgccggcc
     8881 ggcacctcga gcgagaggtc gtcgatcgcg gtgaggccgc cgaagcgcat ggtcaggttg
     8941 cgtaccgaca gcagggtggc gggcgtgttc atcgcgcagc ctcctgggtc gcagcggtct
     9001 tgtcgagcgc gttcaggcgc accgtcggtt cgcggtgggc gagcaggccg cccggacgcc
     9061 acaccatgat cagcaccatc gccaggccga acagcagcat gcggtactcg gcgaagttgc
     9121 gcccgaactc ggggatcagc accagcagcg tggccgccag caccacgccc atctgcgagc
     9181 ccatgccgcc gagcacgacg atggcgagga tgatcgccga ctcggtgaat acgaagctct
     9241 cgggcgagat gaagccctgg cgtgcggcga agaacacccc ggcgaagccg cccagcatgg
     9301 cgccgatggc gaaggccgag agcttgatgt tggtggtgtt catgcccatc gcctggcagg
     9361 cgatctcgtc ctcgcgcagc gcctcccagg cgcggcccac cggcagctt
//
LOCUS       DAOTIN010000124         9389 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_8730_length_9389_cov_8.693486, whole genome shotgun sequence.
ACCESSION   DAOTIN010000124 DAOTIN010000000
VERSION     DAOTIN010000124.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 9389)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 9389)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9389
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_8730_length_9389_cov_8.693486"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1633)
                     /gene="aceE"
                     /locus_tag="P5537_14165"
     CDS             complement(<1..1633)
                     /gene="aceE"
                     /locus_tag="P5537_14165"
                     /EC_number="1.2.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045250 - cytosolic pyruvate
                     dehydrogenase complex [Evidence IEA];
                     GO_function: GO:0004738 - pyruvate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring),
                     homodimeric type"
                     /protein_id="HRV79230.1"
                     /translation="MTGISTVLPQTDTDALETKEWLDALAAVVEHEGPERAHYLIETL
                     IATARQEGVNIPYSATTEYINTIPAERQPPYPGDPDMEIKIHSYIRWNAMAMVVRANK
                     NTNVGGHIASFASAAALYDVGFSHFWHAPSEAHDGDLIYFQGHSVPGVYARAYMLGRF
                     TEEQMDSFRQEVGGKGISSYPHPWLMPDFWQFPTVSMGLGPLCAIYSARFMKYLASRG
                     LIDAARAEQRKVWAFLGDGETDEVESLGAIGMAGREGLDNLVFVINCNLQRLDGPVRG
                     NGKIIQELESEFRGAGWNVIKVVWGTHWDALFARDKKGLLKQRMMALCDGEYQTFKAK
                     DGAYVREHFFNTPELRALVADWTDEQVWNLNRGGHDLFKIYTAYKAASEHKGQPTLIL
                     AKTIKGFGMGQAGEAMNISHQQKKMDVEAIRRFRDRFGLPVPDDKLEELPYLRFAEDS
                     PEHKYLLKHRMDLGGFLPQRRRKAAALEIPGLDAFAALLKASGEGRELSTTMAVVRIM
                     NTLLKDKQIGRHVVPIVPDESRTFGMEGMFRQYGIW"
     gene            complement(1815..3062)
                     /locus_tag="P5537_14170"
     CDS             complement(1815..3062)
                     /locus_tag="P5537_14170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HRV79231.1"
                     /translation="MKPFLALLGRALVTLVLLAPQLSAQAVPAEAVGVGARPSSGERA
                     PIRVGVSGPFSGPSAPMGLSMREGIRIAAAQLNAGGGLLGRRIELVERDDEASNELGA
                     QIVRDFVHRERVIAGLGIVNTGVALASQRHYQMARIPVITSVATGSLITKQFQPPEFP
                     ENYVFRVSASDTLQAAVIVEEAVGRRGLTRLAILHDATNYGVLGSQDLVATLRTRGLA
                     PVAVERFQLRETDMRPQLERARAAGAQAVLTYGIGPELAHIANSMAQLGWQVPMIGSW
                     TLAMSSFIELAGRNAEGARMPQTFIAAARTPAQAAFLAAWELATGSARIPVPPAAAQG
                     YDSMLLLAAAIRQADSLDGPRIREALENLEAEVAGVIMRYRRPFSRDNHETLHSARQI
                     HLGEIRDGAVVFAHEATPDQPRP"
     gene            3257..5965
                     /locus_tag="P5537_14175"
     CDS             3257..5965
                     /locus_tag="P5537_14175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HRV79232.1"
                     /translation="MQASATARATLSRWYWAVPYLAVTVLALSMLAVVWLLQERETEV
                     ERDALARDLQWTEQSIRRAMLTTEEFLVQLARDLSAGTLDHDGFQLRANEHLAINPAL
                     SNLAWVDREHVITWPAPFDTRDLLTGEILVDDQVEAFQNSVLSARLTYGRPYVDSRGA
                     AVLEVFAPVLRRGESLGAIVAVYSLERMLSRLVPARFAEKYRLAILDRAGQVLALSSA
                     LPEAQQPLSLTLALDPPGNGLALQAMAFRPGGAVLRYLPSALIVGLSLVVLWSVWTLR
                     RHVQRRVRVEKERDQLFDLSLDLLCVIDLDGRFGRCNPAFERVLGHDPRSLPGRSLID
                     FVHAEDVAETLSMLRRLASGEPVRFETRCRCADGSYKWLMWSINPVREERLVYAVAHD
                     VTGRKATEDALRAESAFRKAMEDSVVTGLRAIDLSGRIIYVNSAFCRMIGFDEDELVG
                     AGPPFPYWPPEQLAECERNLSMTLSGRAPRSGFEMRILRKNGERFDARFYLSPLIDLT
                     GRQTGWMASITDITEPKRVRAALESAHERFEAVLDGLDAAVFVADARTDEILFANLAF
                     KRIHGFDAVGRTVRGVAVPQPERGDYRVDPRNLSPADVPRELFDGELLHPQSGRWYHV
                     REQATRWVDGRVVRMGIATDITDRKRTAEVAREQEERLQRTARLITMGEMASTLAHEL
                     NQPLAAIANYCAGSVTRLQSGKGRTEDVLAAMQKASFQAERAGKIIRRVREFVKKSEP
                     QRCAVDLVEVLEDAIGFADIDAHRTRIRIHTELAPDLPPVYADRIMIEQVLLNLIRNG
                     LDAMADTLPEARVLTVRVSTVGADAVEVAVIDRGHGISEEGRAQLFTPFYTTKVEGMG
                     MGLNICRSIIEFHNGRLLVDANPEGGTIFTFTLPTESAIERSARSA"
     gene            5940..6578
                     /locus_tag="P5537_14180"
     CDS             5940..6578
                     /locus_tag="P5537_14180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV79233.1"
                     /translation="MSVVPAAPDQIVHVVDDDEALRDSLAWMLEANGHAVAAHESGEA
                     FLAACEPGMTGCVLLDVRMPGMSGLEVFEELGRRRCGLPVVFITGHGDVPMAVSALKQ
                     GAVDFVEKPFGEREMLRVVEQCLRLERETRDRRQQEAETARRLEQLTQREREVLELII
                     VGKLNKQIADVLGISIKTVEVHRARVMEKMGAHSLAELVQHVVALEPGASTR"
     gene            6737..8479
                     /locus_tag="P5537_14185"
     CDS             6737..8479
                     /locus_tag="P5537_14185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HRV79234.1"
                     /translation="MTGINALFLLTGLLLFISVLASTISARLGLPLLLLFLGVGMLAG
                     EDGPGGIVFEDFFIASLIAQAALSVILLDGGLRTRVSSFRVALRPAAVLASWGVIGTA
                     GLLGVFATWLLDVDWRLGMLLAAIVGSTDAAAVFALLRNSGVRLNERVQATLEIESGA
                     NDPMAILLVTALVGMLLQPDTATLGSFVWMLTSQLGLGAILGLAGGWVLSRLMARMSL
                     PDGLYALLILSGGTLVFAATNLLNGSGFLAVYLAGVVVGNRRSHATEHVLRVMDGLAW
                     LAQAGMFVVLGLLVTPSRMIDYLPEALAMAVFLMLVARPLAVAIGLAPFRYPRKELLY
                     VSWVGLRGAVPVVLAIVPVVMGVPDSQLLFNVAFAVVLLSLLVQGATVPMAARWLGVE
                     VPPRDEPRDKREVWVSEVAAVDMLEFCVGAGAKAEGRHPDALGSDHPGHDVRCVALVR
                     EGGLHRLTPDTRLRPGDSVWMIAPDEISEQLARSFAGSRGELTANASFFGEFVVDPDS
                     RASDLADAYGLRIEESERELAMGELLAVRLGRPPVVGDRVEIGAFVLTVREMGDKGRI
                     TALGLKCPPLGGGR"
     gene            8580..>9389
                     /gene="folD"
                     /locus_tag="P5537_14190"
     CDS             8580..>9389
                     /gene="folD"
                     /locus_tag="P5537_14190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase
                     FolD"
                     /protein_id="HRV79235.1"
                     /translation="MTARIIDGNALSAQVRGEIAERAAALTARGVQPCLAVMLVGADP
                     ASAVYVRNKVAGCEKAGIRSLRFDYPDTATQEEVMARLAELNADPSVHGILVQLPLPR
                     HLDETAVLEAIDLKKDVDGFHAENVGRLSQCREAFIPCTPHGVMKMLETAGVQVQGAE
                     AVVIGRSNIVGKPMATLLTNAGATVTVCHSKTKDLAFHTRRADILVAAIGKPRFVTGD
                     MIKPGATVIDVGINRLQDGPDAGKLCGDVDFASVKEVAGAITPVPGGVGPMT"
BASE COUNT         1311 a         3243 c         3307 g         1528 t
ORIGIN      
        1 tccagatgcc gtactggcgg aacatgccct ccatgccgaa ggtgcggctc tcgtccggga
       61 cgatcggcac gacgtggcgg ccgatctgct tgtccttcag gagcgtgttc atgatgcgca
      121 ccaccgccat ggtggtcgac agctcgcgcc cctcgcccga ggccttgagc agcgcggcga
      181 aggcgtccag gccggggatc tccagcgcag cggccttgcg ccggcgctgc ggcaggaagc
      241 cgccgaggtc catgcggtgc ttgagcaggt acttgtgctc gggcgagtcc tcggcgaacc
      301 tcaggtaggg caactcctcg agcttgtcgt cgggcaccgg caggccgaag cggtcgcgga
      361 agcgacggat cgcctcgacg tccatcttct tctgctggtg gctgatgttc atcgcctcgc
      421 cggcctggcc catgccgaag cccttgatgg tcttggcgag gatcagcgtg ggctggccct
      481 tgtgctcgga ggcggccttg taggcggtat agatcttgaa caggtcgtgg ccgccgcggt
      541 tcaggttcca cacctgctcg tcggtccagt cggccaccag cgcgcgcagc tcgggggtgt
      601 tgaagaagtg ctcgcgcacg taggcgccgt ccttggcctt gaaggtctgg tactcgccat
      661 cgcacagcgc catcatgcgc tgcttgagca gacccttctt gtcgcgggcg aagagcgcgt
      721 cccagtgcgt gccccacacc accttgatga cgttccagcc cgcgccgcgg aactcggact
      781 cgagctcctg gatgatcttg ccgttgccgc gcaccgggcc gtccaggcgc tgcaggttgc
      841 agttgatcac gaagaccaga ttgtccaggc cctcgcggcc ggccatgccg atcgcgccca
      901 gcgactcgac ctcgtcggtc tcgccgtcgc ccaggaaggc ccacaccttg cgctgctcgg
      961 cacgcgcggc gtcgatcagg ccgcggctgg cgaggtactt catgaagcgc gccgagtaga
     1021 tcgcgcacag cgggcccagg cccatcgaca ccgtcgggaa ctgccagaag tccggcatca
     1081 gccacgggtg cgggtaggac gagatgccct tgcccccgac ttcctggcgg aagctgtcca
     1141 tctgctcctc ggtgaagcgg cccagcatgt aggcgcgcgc atacacgccc ggcaccgagt
     1201 ggccctggaa gtagatcagg tcgccgtcgt gcgcctcgga gggcgcgtgc cagaagtgcg
     1261 agaagcccac gtcgtagagc gccgcggccg aggcgaagga ggcgatgtgc ccgccaacgt
     1321 tggtgttctt gtttgcccgc accaccatcg ccatcgcgtt ccagcgaatg taggagtgga
     1381 tcttgatctc catgtccgga tcgcccgggt agggcggctg gcgctcggcc ggaatggtgt
     1441 tgatgtactc cgtcgtggcc gagtagggaa tgttcacccc ttcctggcgc gccgtcgcga
     1501 tcagggtctc gatcaggtag tgggcgcgct cggggccttc gtgttcgacg acggcggcca
     1561 gtgcgtccag ccattccttc gtttccagcg catccgtgtc ggtttgcggg agaacggtgc
     1621 tgattccggt catggtttgt ctcctcatga cgttcagttg gcgattcctg tccggcggga
     1681 caggcgggtt gttggttacg ggcacgacca tgccggctgc cgcacggtca gcgtttcaaa
     1741 atataaaacg tcttttcgcg atgtgcaata ggttttcacc tgatgaacga tatttggctc
     1801 cgtgatggct tcattcatgg ccggggctgg tccggcgtgg cctcgtgggc gaacaccacc
     1861 gcgccgtcgc ggatctcgcc gaggtggatc tggcgcgcgc tgtgcaaggt ctcgtggttg
     1921 tcgcgggaga aggggcggcg gtagcgcatg atcacgcccg ccacctctgc ctccaggttc
     1981 tcgagtgcct cgcggatgcg tggaccgtcc aggctgtcgg cctggcggat cgccgcggcg
     2041 agcagcagca tcgagtcgta gccctgcgcg gcggccggcg gcaccgggat gcgggcgctg
     2101 ccggtggcaa gctcccacgc ggcgagaaag gcggcctggg cgggggtgcg cgcggcggcg
     2161 atgaaggtct gcggcatgcg cgcaccctcg gcgttgcgcc cggcgagctc gatgaagctc
     2221 gacatcgcca gcgtccagct gccgatcatc ggcacctgcc agccgagttg ggccatcgag
     2281 ttggcgatgt gtgcaagctc ggggccgatg ccgtaggtga gcacggcctg ggcgccggcg
     2341 gcgcgggcgc gctcgagctg cggccgcatg tcggtctcgc gcagctggaa gcgttcgacc
     2401 gccaccggtg cgagcccgcg cgtgcgcagg gtggcgacga ggtcctggct gccgagcacg
     2461 ccgtagttgg tggcgtcgtg caggatcgcg agccgggtca ggccgcggcg gccgaccgcc
     2521 tcctcgacga tcaccgccgc ctgcagggtg tcgctggcgg agacccggaa gacgtagttc
     2581 tcggggaact cggggggctg gaactgcttg gtgatcagcg agccggtagc caccgaggtg
     2641 atcaccggga tgcgtgccat ctggtagtgg cgctggctgg cgagtgcgac gccggtattg
     2701 acgatgccca gcccggcgat gacccgctcg cgatggacga agtcacgcac gatctgcgcg
     2761 ccgagctcgt tgctggcctc gtcgtcgcgc tcgaccagct cgatgcggcg gccgagcagg
     2821 ccgccgcctg cgttgagttg cgcggcagcg atgcggatgc cttcgcgcat cgacagcccc
     2881 atcggcgccg acgggccgga gaagggcccg gacacgccca cccggatcgg tgcccgctct
     2941 ccgctgctcg ggcgcgcgcc cacccccacg gcctctgccg ggacggcctg cgccgacagc
     3001 tgcggcgcca ggagcacaag cgtcacgagg gcgcgcccga gcagcgcgag gaagggtttc
     3061 attccctcac tctaggcagc gtggccgaac ccacaaattg gcggaaaccc catcgccgcc
     3121 tgctgcgccg ccgcatccac accgggtagg cggaccccga tcagggttac accggatgac
     3181 gcgggcgggc gtgctcgaca acaatcgcca tcccgatcct tgtccccgca ccgctcgccc
     3241 ggccattcct acatccatgc aagcctccgc cactgcccgg gcgaccctgt cgcgctggta
     3301 ctgggccgtg ccctatctcg cggtgaccgt gctcgcgctg tcgatgctcg cggtcgtgtg
     3361 gctgctgcag gagcgcgaga ccgaggtcga gcgcgacgcg ctcgcacgcg acctgcagtg
     3421 gacggagcag tcgatccggc gcgcgatgct caccaccgag gagttcctcg tccagctcgc
     3481 gcgcgacctg tcggcgggca cgctcgatca cgacggcttc cagctgcgcg ccaacgagca
     3541 cctcgcgatc aaccccgccc tgagcaacct cgcctgggtc gatcgcgagc acgtgatcac
     3601 gtggccggcg cccttcgata cccgcgacct gctcaccggc gagatcctcg tggatgacca
     3661 ggtggaggcc ttccagaaca gcgtcctgtc cgctcgcctg acctacggcc ggccctacgt
     3721 cgactcgcgc ggtgccgccg tgctcgaggt ctttgcgccg gtgttgcggc gcggcgaatc
     3781 gctcggggcg atcgtcgcgg tgtattcgct ggagcgcatg ctcagccgcc tggtgccggc
     3841 gcgcttcgcc gagaagtacc gcctcgccat cctcgatcgc gccggccagg tgctcgcgct
     3901 cagctcggcg ctgcccgagg cgcagcagcc gctctcgctc acgctggcgc tcgatccgcc
     3961 cggcaacggc ctggcgttgc aggcgatggc cttccggccc ggcggtgcgg tgctgcgcta
     4021 cctgccgtcc gcgctcatcg tgggcctgtc gctggtggtg ctgtggagcg tgtggacgct
     4081 gcgccgccac gtgcagcgcc gcgtgcgggt ggagaaggag cgcgaccagc tcttcgatct
     4141 ctcgctcgac ctgctgtgcg tgatcgatct cgatggccgc ttcgggcgct gcaacccggc
     4201 cttcgagcgt gtgctcgggc acgatccgcg gtccctgccg gggcgctcgc tgatcgactt
     4261 cgtgcacgcc gaggacgtgg ccgagacgct ttccatgctg cgccggctgg ccagcggcga
     4321 gccggtacgc tttgagacgc gctgccgctg cgccgacggc agctacaagt ggctgatgtg
     4381 gagcatcaac ccggtgcgcg aggagcgcct ggtgtatgcg gtagcgcacg acgtcaccgg
     4441 gcgcaaggcc accgaggacg cgctacgcgc cgagtccgcc ttccgcaagg cgatggagga
     4501 ctcggtggtc accggtctgc gcgcgatcga cctgtcgggg cgcatcatct atgtgaactc
     4561 cgccttctgc cgcatgatcg gcttcgacga ggacgagctc gtcggcgccg ggccgccttt
     4621 cccctactgg ccgcccgagc agctcgccga gtgcgagcgc aacctgtcga tgaccctgtc
     4681 cgggcgcgca ccgcgcagcg gcttcgagat gcgcatcctg cgcaagaacg gcgagcgctt
     4741 cgatgcgcgc ttctacctct cgccgctgat cgacctcacc ggccggcaga ccggctggat
     4801 ggcctcgatc accgacatca ccgagcccaa gcgcgtgcgt gcggcgctcg agtcggcgca
     4861 cgagcgcttc gaggcggtgc tcgacggcct cgacgcggcg gtgttcgtgg ccgatgcgcg
     4921 caccgacgag atcctcttcg ccaacctcgc cttcaagcgc atccacggct tcgacgccgt
     4981 cgggcgcacg gtgcgcgggg tggcggtgcc gcaacccgag cgcggggact accgcgtcga
     5041 cccgcgcaac ctgtcgcccg ccgacgtgcc gcgcgagctc ttcgacggcg aactgctgca
     5101 cccgcagtcg gggcgctggt accacgtgcg cgagcaggcc acgcgctggg tggacgggcg
     5161 ggtggtgcgc atgggcatcg ccaccgacat caccgaccgc aagcggactg ccgaggtggc
     5221 gcgcgagcag gaggagcgcc tgcagcgcac cgcgcgcctg atcaccatgg gcgagatggc
     5281 ctcgacgctg gcgcacgagc tcaaccagcc gctggcggcg atcgccaact actgcgccgg
     5341 ctcggtgacc cggctgcagt cgggcaaggg caggacggag gacgtgctcg ccgcgatgca
     5401 gaaggcgagc ttccaggccg agcgcgccgg caagatcatc cgccgggtgc gcgagttcgt
     5461 gaagaagagc gagccgcagc gctgcgcggt ggacctcgtc gaggtgctgg aggacgcgat
     5521 cggcttcgcc gacatcgacg cccaccgcac ccgcatccgc atccacaccg agctcgcgcc
     5581 cgacctgccg ccggtgtacg ccgaccgcat catgatcgag caggtgctgc tcaacctcat
     5641 ccgcaacggc ctcgacgcca tggccgacac cctgcccgag gcgcgcgtgc tgacggtacg
     5701 ggtgagcacc gtcggggcgg atgcggtcga ggtcgcggtg atcgaccgtg gccacggcat
     5761 cagcgaggag ggcagggcgc agctgttcac ccccttctac accaccaagg tggagggcat
     5821 gggcatgggc ctcaacatct gccgctcgat catcgagttc cacaacggca gattgctggt
     5881 cgacgccaac cccgaaggcg gtaccatatt taccttcacc ctgccgacgg agtccgcaat
     5941 tgagcgtagt gcccgcagcg cctgaccaga tcgttcatgt cgtcgatgac gacgaagccc
     6001 tgcgcgactc gctcgcctgg atgctggagg ccaacggcca cgcggtggcg gcgcacgagt
     6061 cgggcgaggc cttcctcgcc gcctgcgagc cggggatgac cggctgcgtg ctgctcgacg
     6121 tgcgcatgcc gggcatgagc gggctggagg tcttcgagga gctcgggcgg cggcgttgcg
     6181 gactgccggt ggtgttcatc accggccatg gcgacgtgcc gatggcggtg tccgcgctca
     6241 agcagggcgc ggtcgatttc gtcgagaagc ctttcggcga gcgcgagatg ctgcgcgtgg
     6301 tcgagcagtg cctgcgcctc gagcgcgaga cccgcgaccg ccgccagcag gaggccgaga
     6361 ccgcgcgccg gctcgagcag ctcacccagc gcgagcgcga ggtgctcgag ctgatcatcg
     6421 tgggcaagct caacaagcag atcgccgacg tgctcggcat cagcatcaag accgtcgagg
     6481 tgcatcgcgc gcgcgtgatg gagaagatgg gcgcgcattc gctggccgag ctcgtccagc
     6541 acgtggtcgc actcgagccc ggcgcctcca cgcgctgacc ccggcgcgcg caattgcgcg
     6601 ccatggccag acctccgcgg cggcgcgtgc aggaactttt tcccgcccgg gcgtctccgc
     6661 cccaggggcg cgccatcgcc gcgcgcctcg agcaccctcc gaacgtccct cgccagcggc
     6721 tggacccgac ctccgaatga ccggaatcaa cgcgctcttc ctgctcaccg gcctgctgct
     6781 gttcatcagc gtgctcgcca gcaccatctc cgcccggctc ggcctgccgc tgctgctgct
     6841 cttcctcggc gtcggcatgc tcgccggcga ggacgggccg ggcggcatcg tcttcgagga
     6901 tttcttcatc gcctcgctga tcgcccaggc cgcgctctcg gtgatcctgc tcgacggcgg
     6961 cctgcgcacg cgggtgagca gcttccgcgt ggcgctgcgg ccggcggcgg tgctggcgag
     7021 ctggggggtg atcggcaccg cgggcctgct cggcgtgttc gccacctggc tcctcgatgt
     7081 cgactggcgg ctgggcatgc tgctcgcggc gatcgtcggc tcgaccgacg cggccgcggt
     7141 gtttgcattg ctgcgcaaca gcggggtgcg cctgaacgag cgcgtgcagg ccacgctgga
     7201 gatcgagtcc ggcgccaacg acccgatggc gatcctgctc gtcaccgcgc tggtcggcat
     7261 gctgctgcag cccgacaccg ccacgctcgg cagcttcgtc tggatgctga cgagccagct
     7321 cggcctcggc gccatcctcg gcctcgccgg gggctgggtg ctgtcgcggc tgatggcgag
     7381 gatgtcgttg cccgacgggc tgtatgcgct gctgatcctg tccggcggca cgctcgtctt
     7441 cgcggcgacc aacctgctca acggcagcgg cttcctcgcg gtgtatctcg ccggcgtggt
     7501 ggtgggcaac cgccgcagcc acgccaccga gcacgtgctg cgggtgatgg acggcctggc
     7561 ctggctcgcc caggcaggga tgttcgtggt gctgggcctg ctggtgacgc cttccaggat
     7621 gatcgactac ctccccgagg cgctggcgat ggcggtgttc ctgatgctgg tggcgcggcc
     7681 gctggcggtg gcgatcgggc tggcgccctt tcgctatccg cgcaaggagc tgctctacgt
     7741 gagctgggtg ggcctgcgcg gcgcggtgcc ggtggtgctc gcgatcgtgc cggtggtgat
     7801 gggcgtgccg gattcgcagc tgctgttcaa tgtcgccttc gcggtggtgc tgctgtcgct
     7861 gctggtgcag ggggccacgg tgccgatggc tgcgcgctgg ctgggcgtcg aggtgccgcc
     7921 gcgcgacgag ccgcgcgaca agcgcgaggt ctgggtgagc gaggtggcgg cggtggacat
     7981 gctggagttc tgcgtcggcg ccggtgccaa ggccgagggc cgccaccccg acgcgctcgg
     8041 cagcgatcat cccggccacg acgtgcgctg cgtggccctg gtgcgcgagg gcgggctgca
     8101 ccgcctgacc cccgacaccc gcctgcgtcc tggcgactcg gtgtggatga tcgcgcccga
     8161 cgagatctcc gagcagcttg cgcgcagctt cgccggcagc cgtggtgagc tcaccgccaa
     8221 tgccagcttc ttcggcgagt tcgtggttga tcccgacagc cgcgcgagcg acctcgccga
     8281 cgcctacgga ctgcgcatcg aggagtcgga gcgcgaactg gcgatgggcg agctgctcgc
     8341 cgtccgcctc ggccgcccgc ccgtggtcgg cgaccgcgtc gagatcggcg ccttcgtgct
     8401 caccgtgcgc gagatgggcg acaagggccg catcaccgcg ctcggcctca agtgcccgcc
     8461 gcttggcggg gggcgttgat tcgggccgca cgggcggcag catcctcgtg cgaatccgtc
     8521 gtacgggccg tgcccgccgc gatgctgtaa aatccccgct tttttcgggg gcttgaagga
     8581 tgaccgctcg catcatcgac ggcaacgcgc tttccgcgca ggttcgcggc gaaatcgccg
     8641 aacgcgcggc cgcgctcacg gcgcgtggcg tgcagccctg cctggcggtc atgctggtgg
     8701 gcgccgatcc ggcctccgcc gtctatgtgc gcaacaaggt cgccggctgc gagaaggccg
     8761 gcatccgctc gctgcgcttc gactaccccg ataccgccac ccaggaagag gtcatggccc
     8821 ggctcgccga gctcaacgct gacccgtccg tgcatggcat cctggtgcag ctgccgctgc
     8881 ccaggcacct cgacgagacc gcggtgctcg aggccatcga cctgaagaag gacgtcgacg
     8941 gcttccacgc cgagaacgtc ggccgcctgt cgcagtgccg cgaggccttc atcccatgca
     9001 ccccgcacgg cgtcatgaag atgctcgaga ccgccggcgt gcaggtgcag ggcgccgagg
     9061 cggtggtgat cgggcgctcg aacatcgtcg gcaagccgat ggccacgctg ctcaccaacg
     9121 ccggcgccac cgtcaccgtg tgccactcga agacgaagga cctcgccttc cacacccgcc
     9181 gcgccgacat cctggtggcg gcgatcggca agccgcgctt cgtcaccggc gacatgatca
     9241 agccgggcgc caccgtgatc gacgtcggca tcaaccgcct gcaggacggc cccgacgccg
     9301 gcaagctgtg cggcgacgtg gattttgcat ccgtcaagga agtcgccggc gccatcaccc
     9361 cggtgccggg tggagtgggg ccgatgacc
//
LOCUS       DAOTIN010000125         9344 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_8793_length_9344_cov_8.284207, whole genome shotgun sequence.
ACCESSION   DAOTIN010000125 DAOTIN010000000
VERSION     DAOTIN010000125.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 9344)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 9344)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9344
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_8793_length_9344_cov_8.284207"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            320..1783
                     /gene="dbpA"
                     /locus_tag="P5537_14195"
     CDS             320..1783
                     /gene="dbpA"
                     /locus_tag="P5537_14195"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003724 - RNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase DbpA"
                     /protein_id="HRV79236.1"
                     /translation="MSEIPDDTSGRPTGAPDAAVAPPPATGLALPFDHLPLPAAMLDT
                     LRQLDYRATTPIQAASLPLALAGHDLIAQAKTGSGKTAAFGLPLLARLDVRKLAVQAM
                     VLCPTRELADQVTQEIRRLARFEANIKVLALCGGTPMRPQRDSLEHGAHVVVGTPGRI
                     MDHLERGSLKLDALNTLVLDEADRMLDMGFHDDIAFVAGRCPSKRQTLLFSATYPEGI
                     ARLAARFLRQPQEVKLPEQHAHDKIRQRFYEIEHPARLQAVAKLLRHYRPVSTLAFCN
                     TRQQCRDLVELLRAQGFAALALNGEMEQRERDQVLIQFANRSCSVLVATDVAARGLDI
                     AQLEAVINVDVTPDPEIHIHRIGRTGRGEDDGWALNLCSSADKRRVASIAQRMGFEPE
                     WHALDELEEDASEPLQAPMTTLLILGGRKDKIRPADVLGALTGEAGFSREQVGKITVT
                     DQNTYVAVERTIAREAVRRLSAGKLKGKKVKVRALEG"
     gene            1953..2870
                     /locus_tag="P5537_14200"
     CDS             1953..2870
                     /locus_tag="P5537_14200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histone deacetylase"
                     /protein_id="HRV79237.1"
                     /translation="MKLYYADHFVLPLPDGHRFPMEKYALLRARLRASGLFADDDFRV
                     PDAASDTEILRAHDAGYLRRVAGGTLDAAEVRRIGFPWTEAMVERSRRSAGATLAACR
                     SALAREGGSACAANLAGGTHHAHRDFGSGFCVFNDAAVAALAMRAEGRVERVAIVDCD
                     VHQGDGTATILADTPEVFTCSLHGAKNFPFRKQDSDLDVELADDTGDEAYLTALDAAL
                     DTVFTRARPELVIYLAGADPYAGDRLGRLALSIEGLQARDERVLGACRAAGVPVAVAM
                     AGGYAQPIEDTVTVHFNTICTAARTMREA"
     gene            2877..3749
                     /locus_tag="P5537_14205"
     CDS             2877..3749
                     /locus_tag="P5537_14205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004306175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF429 domain-containing protein"
                     /protein_id="HRV79238.1"
                     /translation="MTSLLGIDFTSAPRRAKPITVAHGRLEGARVVLDHIERCSDWTS
                     FEAVLARPGAWLGAFDFPFGLPREAVVDLGWPQDWQELVRHCAAMGKPAFRAALDAYR
                     ETRPAGRRYAHRSTDLPARSHSPLKLVNPPVGLMFLEGAPRLLAASVHIPGMYAGDPA
                     RVAIEAYPGLLARRITPASYKSDERRKQTPERRAARAAIVDALVRGAPSSGGPQPAPA
                     LHATPAQREALVEDASGDLLDAVLALLQAAAAARQGAPRFGLPADFDPIEGWIGGCSV
                     ASNRQRDGIGSAAQ"
     gene            complement(3743..4744)
                     /locus_tag="P5537_14210"
     CDS             complement(3743..4744)
                     /locus_tag="P5537_14210"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79239.1"
                     /translation="MPIQRCNQCGQTGEVLDILPGTTAPCPACKAEAPVYDTSFFVRR
                     LLEQYGTLHKEVKRLRALHAEPQPVMSDQGAQGGGKLAELDLHNTSALAAAAQHAPIV
                     EWFRQRRIEAKPVPEAVETSGFFDEIAVEIGDHYDLLGEVVSRIRWGQRKDVPTFSLK
                     LSDYSQKDGQFVNAFCKRLYDHTFLAKYFYQKPEKMVRVTLQQAAPVRDFFAGEWVEW
                     YVLMKALVQLQEARRDAAFARNLDIVFENEDLHELDVFILLDGAKPIVVECKSGEFRQ
                     DIEKYLKLRRRLGIDRSQFIVFSPDLAEDQAAALSNMYELTFANRERLTAHLRSLIH"
     gene            4852..5625
                     /locus_tag="P5537_14215"
     CDS             4852..5625
                     /locus_tag="P5537_14215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV79240.1"
                     /translation="MTFLLEARTIDKRFGGLQALAGVSLSILKGEIYGLIGPNGAGKT
                     SFFNALTGIHPPDAGEFLLDGAPLPTTRPQAVVARGIARTFQNIRLFRELSVLENVMA
                     ARHRHTRAGLWSVLAGTRASRAEERACAEEAHALLEYVGIDRLAGSLAHSLSYGDQRR
                     LEIARALATAPRLLALDEPAAGMNATETAALGELIRRIRADGVTVLLIEHDVHLVMGL
                     CDRVAVLDFGRKIAEDVPAAVQRDQAVIDAYLGGGRHAA"
     gene            5615..6409
                     /locus_tag="P5537_14220"
     CDS             5615..6409
                     /locus_tag="P5537_14220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018604477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV79241.1"
                     /translation="MPPEATSPLLALRRLEVAHGGIPAVRGIDLEVRAGEIVCLIGAN
                     GAGKSTTLNAIAGLLPCAGGEIHYAGARIDTLPPHRRVAAGIALVPEGRGIFGRLTVE
                     ENLRLGAWTRGNEAALAEDRERICSLLPQLASRRGQLAGTLSGGEQQMLAVGRALLSR
                     PRLLLLDEPSMGLAPRVVEDIFTLIGKIARDGVALLLVEQNARLALELADRGYVMEGG
                     RIVLAGAGGDLLRDPRVRSAYLGERPEGSFTACAAPAQAPEARWFL"
     gene            6531..7550
                     /locus_tag="P5537_14225"
     CDS             6531..7550
                     /locus_tag="P5537_14225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF475 domain-containing protein"
                     /protein_id="HRV79242.1"
                     /translation="MQNLKYFTWSIGFTVIGLVGGYLLGGWPAAFIVAVLAVLETSLS
                     FDNAVVNATVLRHMDEKWRQRFLLWGILIAVFGMRIVFPLAIVGVVASMGPVEVVDLA
                     LFNPDEYARLLTSAHHEIAAFGGAFLMMVFLKFFIDENKDTHWLAPIESPLTKLGRLE
                     AAQILLTLLAILATSAWMDGAEKRMEFIVAGVWGLIVYIMADGLGAIMGGEEGEGGKM
                     VAKTGFAGFMYLELLDASFSFDGVIGAFALTTSLPIIAIGLGVGAMFVRSFTLMLVYR
                     GTLEAYRYLEHGAFWAIGALAAIMFIGVHMHIPETFTGLIGAVLIGAAFWSSLRHNRI
                     ASSGS"
     gene            complement(7625..8230)
                     /locus_tag="P5537_14230"
     CDS             complement(7625..8230)
                     /locus_tag="P5537_14230"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79243.1"
                     /translation="MDCIAGRERIMLSTSMKLGTQLLGLSTLINSGRPAFDGCYRVIA
                     LGGTTVIEFFERAPGNGEHPVRFLPYRTEKIAEAALAGREVISGEFTGCVMASFKVGD
                     ALYAGHVDTNKATSQRAEWDRRKSAGLAVVSEYDTTGKIQDAHGAAAVILCVADGGTG
                     AISHFHVSKTRYQYGHHRAANAPITEYKFDTLYTVISSAGY"
     gene            8479..9105
                     /locus_tag="P5537_14235"
     CDS             8479..9105
                     /locus_tag="P5537_14235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysE family translocator"
                     /protein_id="HRV79244.1"
                     /translation="MLTPDQLLGFLLAAVLVTISPGPDNLMVLGTGMSRGRASGIAFG
                     LGCALGCLSHTALAVIGVGALIAASPTAFTALKICGGLYLLWLGYGALRSGGGARVDT
                     AVQSERSLGALFMKGVIANAINPKVVLFFLSFLPQFVAPARGDAAWQMASLGVVFTMQ
                     AALLFGLLGYFAGSVGQWINRRPRAGQWLDRLAGTIFVALGLRLIVTR"
BASE COUNT         1388 a         3431 c         3073 g         1452 t
ORIGIN      
        1 tgccggggct ccggaatgca cgaaaactca tcgtctcggc tcggcggctt gtaggagcgc
       61 cggcaggcgc gaaaaaatgt cgtccccgct cggcgcactg tagcggcgcc ggcaggcgcg
      121 aacaaggctg caaagacgcg atgccgtctg actcctgcgc tgccctgctc gcacttgcca
      181 acgcgccgac agaacgccat cttggcctcg acgagtctga agcgcgaatc cgcccgaagt
      241 tcccaccccc gggacaagcc gattcactcc gccgcaaagt tttcagcggc ggcgctcgaa
      301 tcaggcctga taattgcgca tgagcgaaat tcctgacgac acctccgggc gccctaccgg
      361 cgcacccgac gcggccgtgg ctccaccccc tgccaccggg ctcgccctgc ccttcgacca
      421 cctgcccctg cctgcggcca tgctggacac cctgcgccag ctcgactatc gcgcgacgac
      481 cccgatccag gccgccagcc tgccgctggc gctcgccggg cacgacctca tcgcccaggc
      541 caagaccggc agtggcaaga ccgcggcctt cggcttgccg ctgctcgccc ggctcgacgt
      601 gcgcaagctc gccgtgcagg ccatggtgct gtgccccacc cgcgagctgg ccgaccaggt
      661 cacgcaggag atccgccgcc tggcgcgctt cgaggccaac atcaaggtgc tggcgctgtg
      721 cggcggcacg ccgatgcgcc cgcagcgcga cagcctggag cacggcgccc acgtcgtggt
      781 cggcacgccc ggacgcatca tggaccacct cgagcgcggc agcctgaagc tcgacgcgct
      841 gaacaccctg gtgctggacg aggcggaccg catgctggac atgggcttcc acgacgacat
      901 cgccttcgtc gccgggcgct gcccgtcgaa acgccaaacc ctgctgttct cggccaccta
      961 ccccgagggc atcgcccgcc tggccgcgcg cttcctgcgc cagccgcagg aggtgaagct
     1021 gcccgaacag cacgcgcacg acaagatccg ccagcgcttc tacgagatcg agcacccggc
     1081 gcgcctgcag gcggtcgcga agctgctgcg ccactaccgc ccggtgagca cgctggcctt
     1141 ctgcaacacc cgccagcagt gccgcgacct ggtcgagctg ctgcgcgccc agggcttcgc
     1201 cgcgcttgcc ctcaacggcg agatggagca gcgcgagcgc gaccaggtgc tgatccagtt
     1261 cgccaaccgc agctgctcgg tgctggtcgc gaccgacgtc gccgcgcgcg ggctcgacat
     1321 cgcccagctc gaggcggtga tcaacgtcga cgtcaccccc gaccccgaga tccacatcca
     1381 ccgcatcggc cgcaccggcc gcggcgaaga cgacggctgg gcgctgaacc tgtgcagcag
     1441 cgccgacaag cgccgcgtcg cgagcatcgc gcagaggatg ggcttcgagc ccgagtggca
     1501 tgcgctcgac gagctggagg aagacgcgag cgagccgctg caggcgccga tgacgacgct
     1561 gctgattctg ggcggacgca aggacaagat ccgcccggcg gacgtgctcg gtgcgctgac
     1621 cggcgaggcc gggttcagcc gcgagcaggt cggcaagatc accgtcaccg atcagaacac
     1681 ctacgtggcg gtcgagcgca cgatcgcgcg cgaggcggtg cgccggctgt cggcgggcaa
     1741 gctcaagggc aagaaggtga aggtgcgcgc actggagggc tgagggtgag gggtgaggcc
     1801 cgagcgggcc ggcggcggtt tatccttggc gcacttcacg ccgcgccgga ggtctgaagc
     1861 cgcagcgaag gcgaagccct gcttcaacca ccccgctcca accgccccgc aactgccccg
     1921 ctctcaccgc attcgaccgg atcctctcca ccttgaagct ctactacgcc gaccacttcg
     1981 tcctgccgct gcccgatggg caccgctttc cgatggagaa atatgccctg ctgcgcgccc
     2041 gcctgcgcgc gagcggactg ttcgccgacg acgacttccg cgtccccgac gcggccagcg
     2101 acaccgagat cctgcgcgcc cacgacgccg gctacctgcg gcgcgtcgcc ggaggcacgc
     2161 tagacgcggc cgaagtgcgg cgcatcggct ttccgtggac cgaggcgatg gtcgagcgct
     2221 cgcggcgctc ggcgggcgcc acgctcgccg cctgccgcag cgcgctcgct cgcgaaggcg
     2281 gcagcgcctg cgccgccaac ctcgccggcg gcacccacca tgcgcaccgc gacttcggct
     2341 cgggcttctg cgtgttcaac gacgccgccg tcgccgcgct ggcgatgcgg gccgagggcc
     2401 gcgtcgagcg ggtagccatc gtcgactgcg acgtgcatca gggcgacggc accgccacca
     2461 tcctcgccga cacccccgag gtgttcacct gcagcctgca cggcgcgaag aacttcccct
     2521 tccgcaagca ggacagcgac ctcgacgtcg agctggccga cgacaccggc gacgaggcct
     2581 acctcaccgc gctcgatgcc gcgctcgaca ccgtgtttac ccgtgcccgc ccggagctgg
     2641 tgatctacct cgccggcgcc gacccctacg ccggcgaccg cctcggccgg ctcgcactca
     2701 gcatcgaagg gctgcaggcc cgcgacgaac gcgtgctcgg cgcctgtcgg gccgccggcg
     2761 tgccggtcgc ggtggcgatg gcggggggct atgcgcagcc gatcgaggac acggtgacgg
     2821 tgcacttcaa caccatctgc accgcggcgc ggacgatgcg ggaggcttga gcgctcgtga
     2881 cttcgctcct cggcatcgac ttcacctccg ctccccgccg cgccaagccg atcaccgtcg
     2941 cccacggccg cctcgaaggc gcgcgcgtcg tgctcgatca catcgagcgc tgttccgact
     3001 ggacgagctt cgaggcggtg ctcgcgcgcc ccggcgcctg gctgggggcc ttcgactttc
     3061 ccttcgggct gccgcgcgag gcggtggtcg acctgggctg gccgcaggac tggcaggagc
     3121 tcgtgcgcca ctgcgccgcc atgggcaagc ccgccttccg cgccgcgctc gacgcctacc
     3181 gcgagacccg ccccgccggc cgtcgctacg cgcaccgcag caccgatctg cccgcgcgct
     3241 cgcacagccc gttgaagctg gtcaacccgc cggtcggcct gatgttcctc gagggcgcgc
     3301 cgcgcctgct cgccgccagc gtccacattc cgggcatgta cgcgggcgat ccggctcggg
     3361 tcgcgatcga ggcctatccc gggctgctcg cgcgccgcat cacgccagcc tcgtacaaga
     3421 gcgacgagcg ccgcaagcag acacccgagc gccgcgccgc gcgtgccgcg atcgtcgacg
     3481 ccctcgtccg cggcgccccg tcttccggcg gcccgcaacc cgcgccggcg ctgcacgcca
     3541 cgcccgcaca gcgcgaggcc ctggtcgagg acgccagcgg cgacctgctc gacgccgtgc
     3601 tcgccctgct gcaggccgct gcggccgccc gccagggtgc gccgcgcttc ggcctgccgg
     3661 cggacttcga cccgatcgag ggctggatcg gtggttgcag cgtggcgtcg aaccgccagc
     3721 gcgacggtat cggatcggct gctcagtgaa tcaagctgcg caggtgggcg gtgagccgct
     3781 cgcggtttgc gaaggtcagt tcgtacatgt tgctcagggc cgcggcctga tcctcagcga
     3841 gatccgggct gaagacgatg aactggctgc ggtcgatccc gaggcgcctg cgcagcttca
     3901 aatacttctc gatatcctgg cgaaactcgc cgctcttgca ctcgaccacg atcggcttcg
     3961 caccgtcgag caggatgaag acatccagtt cgtgaaggtc ctcgttctcg aagacgatgt
     4021 cgaggttgcg cgcaaaggca gcgtcacgtc gcgcctcctg caactggacc aacgccttca
     4081 tcagcacata ccactccacc cactcgccgg cgaagaagtc gcgtacgggc gcggcctgct
     4141 ggagcgtgac acggaccatc ttctccggct tctgatagaa gtacttggcg aggaaggtgt
     4201 ggtcgtacag gcgcttgcag aaggcattga cgaactgacc gtccttctgg ctgtagtcgg
     4261 agagcttgag gctgaaagtc ggaacgtctt tgcgctggcc ccagcggatc ctggagacga
     4321 cttcgccgag caggtcgtaa tggtcgccga tctcgaccgc gatctcgtcg aagaagccgg
     4381 acgtctcgac tgcttcggga accggcttcg cctcgatgcg acgctggcgg aaccattcga
     4441 cgatcggggc gtgctgggcg gccgcggcga gcgcggaggt gttgtggagg tcgagttcgg
     4501 cgagtttgcc gccgccctgc gcgccctggt ccgacatcac cggctgtggc tcggcatgga
     4561 gcgccctcaa acgcttcacc tccttgtgaa gcgtgccgta ctgctcgagc agcctgcgca
     4621 cgaagaagct ggtgtcgtag accggtgcct cggccttgca ggcgggacag ggcgcggtcg
     4681 ttccgggcag aatgtcgagc acctcgccgg tctggccaca ttgattacag cgctggatgg
     4741 gcattacgaa ggctccgcag ctcctttcga aaggcgcgat tatagccacg ccgccacgag
     4801 caccgctgcc aaccatgaca tgaacgtgga acgataccca cggcattgcc gatgaccttc
     4861 ctgctcgaag cccgcaccat cgacaagcgc ttcggcggcc tgcaggcgct cgccggcgtc
     4921 tcgctgtcca tcctcaaggg cgagatctac ggcctcatcg gcccaaacgg cgcaggcaag
     4981 accagcttct tcaacgcgct cactggcatc cacccacccg acgccggcga gttcctgctc
     5041 gacggcgcgc ccctgcccac gacgcggccg caggcggtgg tagcgcgcgg catcgcccgc
     5101 accttccaga acatccgcct gttccgcgag ctgagcgtgc tggagaacgt catggccgcg
     5161 cgccaccgcc acacccgcgc cgggctgtgg agcgtgctcg ccggcacccg cgccagccgc
     5221 gccgaggagc gcgcctgcgc cgaggaggcg cacgccctgc tcgaatacgt cggcatcgac
     5281 cggctcgccg gcagcctcgc gcacagcctc tcctacggcg accagcgccg cctcgagatc
     5341 gcgcgcgcgc tcgccaccgc cccgcgcctg ctcgcgctcg acgagcccgc cgccggcatg
     5401 aacgccaccg agaccgccgc gctcggcgag ctgatccgcc gcatccgcgc cgacggcgtc
     5461 accgtgctgc tgatcgagca cgacgtacac ctggtgatgg gcctgtgcga ccgcgtcgcg
     5521 gtgctcgact ttggccgcaa gatcgccgag gacgtgcccg ccgccgtaca gcgtgaccag
     5581 gccgtcatcg acgcctacct gggcgggggc cgccatgccg cctgaggcaa cgagccccct
     5641 gctggcgttg cgccggctgg aagtcgcgca tggcggcatt ccggccgtgc gcggcatcga
     5701 cctcgaagtg cgcgccggcg agatcgtctg cctgatcggc gccaacggcg ccggcaagag
     5761 caccacgctc aacgccatcg ccggcctgct gccttgcgcc ggcggcgaga tccactacgc
     5821 cggcgcacgc atcgacacgc tgcccccgca ccgccgcgtc gccgccggca tcgccctcgt
     5881 gcccgagggg cgcggcatct tcggccgcct caccgtggaa gagaacctgc gcttgggcgc
     5941 gtggacgcgc ggcaacgagg ccgcactcgc cgaggatcgc gagcgcatct gctcactgct
     6001 gccccagctc gccagccgcc gcggacaact cgccggcacg ctctcggggg gcgagcagca
     6061 gatgctcgcg gtcggccgcg ccctgctgtc gcgcccgcgc ctgctgctgc tggacgaacc
     6121 ctcgatgggc ctggcgccca gggtggtcga ggacatcttc accctgatcg gcaagatcgc
     6181 gcgcgacggc gtcgccttgc tgctcgtgga gcagaacgcg cgactggcgc tggagctggc
     6241 tgatcgcggg tatgtgatgg agggcggccg catcgtgctc gcaggcgccg gaggcgatct
     6301 gctgcgggat cccagagtgc gctcagccta cctcggcgaa cgcccggaag gatcattcac
     6361 ggcttgcgcc gctcctgcac aggccccgga agcacgttgg tttctgtagg agcgccggca
     6421 ggcgcgaaag ccgcgcctcg gaaaaccgca tcaccacccc gcccgtgaag cgataagatt
     6481 gcgcccctcg cgatgcactg ggcgcgtcgc ctgctcccac cggaccctcg atgcaaaacc
     6541 tcaagtactt cacctggtcg atcggcttca ccgtcatcgg gctcgtcggc ggctacctgc
     6601 tcggcggttg gcccgccgcc ttcatcgtcg ccgtgctcgc ggtgctggag acctcgctgt
     6661 ccttcgacaa cgcggtggtc aacgccaccg tgctgcgcca catggacgag aagtggcgcc
     6721 agcgcttcct gctgtggggg atcctgatcg cggtcttcgg catgcgcatc gtgttcccgc
     6781 tcgcgatcgt cggcgtggtg gcgagcatgg ggccggtcga ggtggtcgat ctcgcgctct
     6841 tcaaccccga cgaatacgcc cgcctgctca cctccgcgca tcacgagatc gcggccttcg
     6901 gcggcgcctt cctgatgatg gtcttcctca agttcttcat cgacgagaac aaggacaccc
     6961 actggctggc gccgatcgag agtccgctga ccaagctcgg ccgcctggaa gccgcgcaga
     7021 tcctgctgac gctgctcgcc atcctcgcca cctcggcgtg gatggacggc gcggagaagc
     7081 gcatggagtt catcgtcgcc ggggtgtggg gcctgatcgt ctacatcatg gccgacggcc
     7141 tgggcgcgat catgggcggc gaggagggcg agggaggcaa gatggtcgcc aagaccggct
     7201 tcgcgggctt catgtacctg gagctgctgg acgcatcctt cagcttcgac ggcgtcatcg
     7261 gcgccttcgc gctcaccacc agcctgccga tcatcgccat cggcctgggc gtgggcgcga
     7321 tgttcgtgcg ctcattcacg ctgatgctgg tgtatcgcgg caccctcgaa gcctaccgct
     7381 acctggagca cggggccttc tgggcgatcg gcgcgctggc ggcgatcatg ttcatcggcg
     7441 tgcacatgca catccccgag accttcaccg gcctgatcgg cgcggtgctg atcggcgcgg
     7501 cgttctggag ctcgcttcgg cacaaccgta tcgcctcgag cggaagctga atgcgctgcg
     7561 caggccctgc accgttttcg aggcgcgggg cctgcgcgag cgctggacgg ctccgccgcc
     7621 tgactcaata accggcggaa gagatcaccg tgtacagcgt atcgaacttg tattcggtaa
     7681 tcggcgcgtt cgccgcgcgg tgatgcccgt actggtagcg cgtcttgctg acgtggaaat
     7741 ggctgatcgc tcccgtgccg ccgtccgcca cgcacaggat gaccgcagcg gcgccgtgcg
     7801 catcctggat cttgcccgtc gtgtcgtact ccgagacgac cgccagcccg gcggactttc
     7861 gcctgtccca ttccgcccgc tgcgatgtcg ccttgttcgt gtccacgtgg ccggcgtata
     7921 gcgcgtcccc gaccttgaac gaagccatca cgcaaccggt gaactcgccg ctgatgacct
     7981 ctcgaccggc aagcgccgcc tccgcgatct tctcggtgcg gtagggcaga aagcggaccg
     8041 ggtgctcgcc attgcccggc gcacgctcga agaactcgat caccgtcgtc cctccgaggg
     8101 cgatcacgcg ataacaccca tcgaatgccg gcctgccgga gttgatcagc gtgctgaggc
     8161 ccagcaactg cgttcccagc ttcatcgacg tcgacaacat gatccgctcc ctcccggcga
     8221 tgcaatccat ttgatcctag catcgcagta acgggctcgc tgccccgaat tggacgctat
     8281 cgagaaggcg aacgccaccg gcggaccacc cgctcgtcgc ggatcgtctg caggcgtgca
     8341 gggccggcgt tcttgcgcgg gacctggaaa gctccatcgc ggctccgcgc tctgcgcatg
     8401 gacgccgagg ggtaagattc ccgccagccg gccccaccgg atcgccctcg cccacccacc
     8461 acgcgtacgc ccgattccat gctcacgcca gaccagctcc tcggttttct cctcgccgcc
     8521 gtcctcgtca ccatctcgcc cggacccgac aacctgatgg tgctgggcac cggcatgtcc
     8581 agggggcgcg cgagcgggat cgcgttcggg ctgggatgcg cgctgggctg cctgagccac
     8641 acggcgctcg cggtgatcgg ggtcggtgcg ctgatcgcgg cgtcaccgac ggccttcacc
     8701 gcactgaaga tctgcggcgg cctctacctg ctatggctgg gctacggcgc gctgcgcagc
     8761 ggtggcggag cgcgggtcga caccgcagtg cagtccgagc gctcgctcgg ggcgctgttc
     8821 atgaagggcg taatcgccaa tgcgatcaac cccaaggtgg tgctcttctt cctgtccttc
     8881 ctgccccagt tcgtcgcccc cgcgcgcggc gacgcggcgt ggcagatggc gtcgctcggg
     8941 gtggtgttca ccatgcaggc ggcgctgctg ttcggtctgc tcggatactt cgccggcagc
     9001 gtcgggcagt ggatcaaccg ccgcccgcgc gccggccagt ggctcgaccg cctcgccggc
     9061 acgatcttcg tcgcgctcgg gctgcggctg atcgtcacgc gctgaacggc cgcgttcgcg
     9121 cctgccggcg ctcctacatg aggcgctgcg gttccttggc cgcgttcgcg cctgccggcg
     9181 ctcctacacg aggcggcgcg gttccttggc cgcgttcgcg cctgccggcg ctcctgcatg
     9241 aggcggcgcg gttccttggc cgcgttcgcg cctgccggcg ctcctgcatg aggcggcgcg
     9301 gttccttggc cgcgttcgcg cctgccggcg ctcctacatg aggc
//
LOCUS       DAOTIN010000126         9006 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_9233_length_9006_cov_8.232041, whole genome shotgun sequence.
ACCESSION   DAOTIN010000126 DAOTIN010000000
VERSION     DAOTIN010000126.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 9006)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 9006)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9006
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_9233_length_9006_cov_8.232041"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..941)
                     /gene="carB"
                     /locus_tag="P5537_14240"
     CDS             complement(<1..941)
                     /gene="carB"
                     /locus_tag="P5537_14240"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002928135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006807 - nitrogen compound metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HRV79245.1"
                     /translation="MPKRTDIKSILIIGAGPIIIGQACEFDYSGAQACKALREEGYKV
                     ILVNSNPATIMTDPETADVTYIEPITWQVVERIIDKERPDAILPTMGGQTALNCALDL
                     GRHGVLAKYGVELIGASEEAIDKAEDRLKFKDAMTRIGLGSARSGIAHSMEEALQVQG
                     GIGFPVIIRPSFTLGGTGGGIAYNMEEFQEICKRGLEASPTNELLIEESLLGWKEYEM
                     EVVRDRADNCIIVCSIENLDPMGVHTGDSITVAPAQTLTDKEYQIMRNASIAVLREIG
                     VDTGGSNVQFAINPKDGRMIVIEMNPRVSRSSALASKA"
     gene            complement(1031..2173)
                     /gene="carA"
                     /locus_tag="P5537_14245"
     CDS             complement(1031..2173)
                     /gene="carA"
                     /locus_tag="P5537_14245"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005951 - carbamoyl-phosphate synthase
                     complex [Evidence IEA];
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HRV79246.1"
                     /translation="MSAFPPAILALADGTVFHGKGIGAVGSTVGEVVFNTSMSGYQEI
                     LTDPSYCRQIVTLTYPHIGNTGINPEDVESTRVQAAGLVIRDLPILPSNFRMTQRLDD
                     YLRAENVVAIAGLDTRKLTRVLREKGAQAGSIVTATVGQALDAEAAVAQARAFPGLAG
                     MDLAKVVSASARYEWKQAEWALEGGYSDRADGRFHVVAYDFGVKYNILRMLVERGCRL
                     TVVPAQTPAAEVLALSPDGVFLSNGPGDPEPCDYAIAAIREILSARVPTFGICLGHQL
                     LALASGAKTMKMKFGHHGANHPVKDLDSGQVLITSQNHGFAVDPSTMPASLRVTHQSL
                     FDGSNQGIARTDVPAFSFQGHPEASPGPHDVAYLFDRFIGLMEAGK"
     gene            complement(2322..4823)
                     /locus_tag="P5537_14250"
     CDS             complement(2322..4823)
                     /locus_tag="P5537_14250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV79247.1"
                     /translation="MSGAPDTRGNPSGPASVEAELARLRGERDAALRALSSARRHLDL
                     VSANAGAGVWHKDLASGAIRLDERWRRLLGYEGTEATDWMALVDEEGRSALQQALRAH
                     LGGDADELRAEIRIRAQDGSWHWIEVCGNAGGRGEDGRWSRVEGTYRDVTERKLREIE
                     LLEAKEAAEAASRAKGDFLANMSHEIRTPMNGIIGMTDLLLDSPIAGEQREYLQTVKS
                     SAEALLTIINDILDFSRIEAGRLSVEQIDFSLQSVVSETCRALALRAAQKGLELYYDI
                     GADVPSVLRGDPTRLRQILVNLIGNAIKFTDRGEVEVRVRCIERNGSMASLEFLVRDT
                     GCGIAPDKLEAIFGAFSQADNSTTRKYGGTGLGLAICRQLSELMGGRIGVDSVPDAGS
                     RFEVVLPLRLVADPAPLRAGVLAGARVLVASASAAFGDFLCATLQAAGLRAEAACGGE
                     IAVQALARAADGSDPFAFLLMDADLPEPGGFALAQRFAAAWPRPDRIIPMMASHSQRN
                     DALRCEELGLGFRLAKPFSAEDLLAVLRMAQGGEREATEPPPFELAPVELRSSVGVER
                     PARVLEVLVVEDNPVNQTVARRMLEHAGHSVAVANNGEEALEAIEARHFDVVLMDVQM
                     PVMGGIEATQAIRAREARRSWVLEGDWRPVPIIAMTAHAMEGDRERCLEAGMDDYVSK
                     PVHPEALFAAIERALGPAGGEEVGSDITLLELDAADRRRIACLDEARAMFEGDEGVVE
                     QLVEVFLRDLPRTVADLHKGAADMDFERLRALGHMIKGSVGVFSAQRAVDAARRLEDL
                     AAAGDPRALTSQAGLAAREIELLGEVLREEAAGGS"
     gene            complement(4832..5638)
                     /gene="dapB"
                     /locus_tag="P5537_14255"
     CDS             complement(4832..5638)
                     /gene="dapB"
                     /locus_tag="P5537_14255"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002928128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HRV79248.1"
                     /translation="MSQIRVAIAGASGRMGRMLIEAALKEEGVVLAAAFDRSDTPFIG
                     RDAGEMAGVATGVLITDDAAAAIAAADCVIDFTRPEGTLAHLALARAAGKAMVIGTTG
                     FDATGKAAIAAAAEHVPVVFAPNMAVGVNAVFRLLEVAARILAEGYDVEVIEAHHRFK
                     VDAPSGTALRMGEVVARELGRDLETCAIYGREGHTGERSAETIGFSTIRGGDVVGDHT
                     VLFAGIGERIEITHKSGSRMPYALGSMRAARFLAGRAQGLYDMQDVLGLR"
     gene            complement(5705..6112)
                     /locus_tag="P5537_14260"
     CDS             complement(5705..6112)
                     /locus_tag="P5537_14260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamE"
                     /protein_id="HRV79249.1"
                     /translation="MRSFLAALVVSSGLISGCSFDSVVGLVDPYRIDVRQGNYVDQEM
                     VAQLRRGMTREQVRYVLGSPLVVDMFRSDRWDYVYRFRPGSGEAQQRVISLFFAGDVL
                     DRIEGDVAAASAAPEAVPQQRSRVVEIPPAAGR"
     gene            6362..6802
                     /gene="fur"
                     /locus_tag="P5537_14265"
     CDS             6362..6802
                     /gene="fur"
                     /locus_tag="P5537_14265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004387629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferric iron uptake transcriptional regulator"
                     /protein_id="HRV79250.1"
                     /translation="MSDNSRNLKSIGLKATYPRLKILDLFQSSEQRHLTAEDVYRTLM
                     NEGMDIGLATVYRVLTQFEQAGLLERHYFESGKAVFELNEGGHHDHLVCMQCGKVEEF
                     FDAEIERRQNQIATERGFAIREHALYIYADCQRENCPNLEREKD"
     gene            complement(6804..8459)
                     /gene="recN"
                     /locus_tag="P5537_14270"
     CDS             complement(6804..8459)
                     /gene="recN"
                     /locus_tag="P5537_14270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HRV79251.1"
                     /translation="MLRCLTIRDFVIVDRLDLEFATGFGALTGETGAGKSILLDALGL
                     ALGGRGEAAMVRSGRDRADVAAEFDLPAAEGLVAWLAEQALPADEGVLILRRTIDAGG
                     RSRAWINGVAATLAQLRAAGEWLADIHGQHAHHALLRADAQRDLLDAQAGAGALVAEV
                     AARHREWQRLLRLQREAEADSASSARERELLAWQLRELEQVGFDSDEWAELNAEHGRL
                     AHAASLIEGAEEAVVALGEGELSVCSVLGRLDGRVAALADFDAGLADVRELISAAAIQ
                     ADEALHALRRYRDRLDLDPGRLAELERRIAAVMEAARKYRVQPEELPALGQQWRERLD
                     TLEATADPARLAAAAQAAQAAYDAAAAKLTAARIPAARRLSEEIAAAMQDLAMAGGRF
                     EVALEPCSPSASGVEAVEFRVAANAGQPLRSLAKVASGGELSRIGLAIQVITSRDSAV
                     PTLIFDEVDVGIGGRVAEIVGKLLARLGRDRQVLCVTHLPQVAACADWQWRIAKRDQG
                     GETLSEVTPLDDATRVEEIARMLGGVNITATTREHAAEMLGRR"
     gene            complement(8523..>9006)
                     /locus_tag="P5537_14275"
     CDS             complement(8523..>9006)
                     /locus_tag="P5537_14275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004381117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HRV79252.1"
                     /translation="VLRGGARVFHTLALNDVVVNKGELGRMIEFELSIDEEFVYTQRS
                     DGMIVSTPTGSTAYALSANGPILHPSVGGIALVPLCPHALTARPITLPDSCRIDIALL
                     PPHDARVHFDGQTRFDLRAGDCVRLTRSSRSLRLLHPKGYSYFAMLRQKLHWSAAPRV
                     "
BASE COUNT         1356 a         3176 c         3145 g         1329 t
ORIGIN      
        1 gccttggagg ccagcgccga ggagcgcgac acgcgcgggt tcatctcgat gacgatcatg
       61 cgaccgtcct tcgggttgat ggcgaactgg acgttcgagc caccggtatc caccccgatc
      121 tcgcgcagca ccgcgatcga ggcgttgcgc atgatctggt attccttgtc ggtgagcgtc
      181 tgcgccggcg cgacggtgat cgagtcgccg gtgtgcacgc ccatcgggtc gaggttctcg
      241 atcgagcata cgatgatgca gttgtcggcg cggtcgcgca cgacctccat ctcgtattcc
      301 ttccagccca gcagcgactc ctcgatcagg agctcgttgg tcgggctggc ctcgagaccg
      361 cgcttgcaga tctcctggaa ctcttccatg ttgtaggcga tgccgccgcc ggtgccgccg
      421 agcgtgaagc tcgggcggat gatcaccggg aagccgatgc cgccctggac ctgcagcgcc
      481 tcttccatgc tgtgggcgat gcccgagcgc gccgagccga gaccgatcct ggtcatcgcg
      541 tccttgaact tgaggcggtc ctcggccttg tcgatcgcct cttccgaagc gccgatgagc
      601 tcgacgccgt acttggcgag cacgccgtgg cggccgaggt cgagcgcgca gttgagcgcg
      661 gtctggccgc ccatggtcgg caggatcgcg tcggggcgct ccttgtcgat gatgcgctcg
      721 accacctgcc aggtgatcgg ctcgatgtag gtgacgtcgg ccgtctccgg gtcggtcatg
      781 atggtcgccg ggttcgagtt gaccaggatg accttgtagc cttcctcgcg cagcgccttg
      841 caggcctggg cgccggaata gtcgaactcg caggcctggc cgatgatgat cgggccggcg
      901 ccgatgatca ggatgctctt gatgtctgta cgcttgggca ttgtcttgcc tcggtgattc
      961 ctcgacgccg cgccgatcgc gcgcatcgga atgaactggg gcggcgggcc ctcgcccgcc
     1021 gcggaacgtc ttacttgcct gcttccatca ggccgatgaa gcggtcgaac aggtaggcga
     1081 cgtcgtgcgg gccggggctc gcctcggggt ggccctggaa ggagaaggcc ggcacgtcgg
     1141 tgcgcgcgat gccctggttg gagccatcga agagcgactg gtgggtcacg cgcaggctcg
     1201 ccggcatggt cgacggatcg actgcgaagc cgtggttctg gctggtgatc agcacctggc
     1261 cgctgtcgag gtccttgacc gggtggttcg cgccatggtg gccgaacttc atcttcatgg
     1321 tcttcgcgcc ggaggcgagc gccagcagct ggtggccgag gcagatgccg aaggtcggca
     1381 cgcgcgcgga gaggatctcg cggattgccg cgatcgcgta gtcgcagggc tcggggtcgc
     1441 ccggcccgtt ggacaggaac acaccgtccg gactcagcgc cagcacctcg gcggcgggcg
     1501 tctgcgccgg caccacggtg aggcggcagc cgcgctcgac cagcatgcgc aggatgttgt
     1561 acttgacgcc gaagtcgtag gcgacgacgt ggaagcgccc gtcggcgcgg tcgctgtagc
     1621 cgccctcgag cgcccactcg gcctgcttcc actcgtagcg cgcgctggcg ctgacgacct
     1681 tggcgaggtc catgcccgcg aggccgggga aggcgcgcgc ctgggccacg gcagcctcgg
     1741 cgtcgagcgc ctggcccacg gtagcggtga cgatggagcc cgcctgcgcg cccttctcgc
     1801 gcagcacgcg ggtgagcttg cgggtgtcga gcccggcgat cgcgaccacg ttctcggcgc
     1861 gcaggtagtc gtccaggcgc tgggtcatgc ggaagttgga cggcaggatg ggcaggtcgc
     1921 ggatgaccag gccggccgcc tgcacgcggg tggactcgac gtcctcgggg ttgatgccgg
     1981 tgttgccgat gtgcggatag gtcagggtga cgatctggcg gcaatagctc gggtcggtca
     2041 ggatttcctg ataccccgac atcgaggtgt tgaacaccac ctcgccgacc gtgctgccaa
     2101 ccgcgccgat acccttgccg tggaagacgg ttccgtcggc gagcgcaaga atggcgggcg
     2161 ggaatgcact cacgagaagc tcctggaatc tgctggaagt cttgcaggcg cgcgaacggc
     2221 gcgcccgata tgtacaaaaa gcgggacggg cctccgggcc gatcccgctt cgaaaacctt
     2281 gtaattgtac attttcggcg gattcaaggc aaacagcccg ctcaactgcc gccagccgcc
     2341 tcttcccgca gcacctcgcc gagcagctcg atctcgcgtg ccgcgaggcc cgcctggctg
     2401 gtcagcgcac gcgggtcgcc ggccgcagcg aggtcctcga gccggcgcgc ggcgtcgacc
     2461 gcacgctgcg ccgagaacac ccccaccgag cccttgatca tgtgaccgag cgcgcgcagg
     2521 cgttcgaaat ccatgtcggc cgcgcccttg tgcaggtccg cgaccgtgcg tggcagatcg
     2581 cgcaggaaca cctcgacgag ttgctcgacg accccttcgt cgccttcgaa catcgcacgc
     2641 gcctcgtcca gacaggcgat gcggcgacgg tcggccgcgt ccagctcgag cagggtgatg
     2701 tcgctgccca cctcctcccc gcccgccggg ccgagcgcgc gctcgatcgc ggcgaacagc
     2761 gcctcggggt ggaccggctt ggagacgtag tcgtccatgc cggcctcgag gcagcgctcg
     2821 cgatccccct ccatcgcatg cgcggtcatc gcgatgatcg gcaccggcct ccagtcgccc
     2881 tcgagcaccc agctgcgcct cgcctcgcgc gcgcggatcg cctgcgtggc ctcgatgccg
     2941 cccatcacgg gcatctgcac gtccatcagc accacgtcga agtgacgagc ctcgatcgcc
     3001 tcaagggcct cctcgccgtt gttcgccacg gccacgctgt ggcctgcgtg ctcgagcatg
     3061 cgtcgggcca cggtctggtt cacagggttg tcctcgacca ccagcacttc gagcacccgc
     3121 gcgggccgct cgaccccgac actcgagcgc aactcgaccg gcgcgagctc gaagggcggc
     3181 ggctcggtag cctcgcgctc gccgccctgc gccatgcgca gcacggccag caggtcttcg
     3241 gcggagaagg gcttggcgag acgaaaaccg agcccgagct cttcacaacg cagggcatcg
     3301 ttgcgctgcg agtggctcgc catcatcggg atgatgcggt ccggtcgcgg ccacgcggcg
     3361 gcgaagcgct gcgccaacgc gaagccgccc ggttccggca ggtccgcatc catcagcagg
     3421 aaggcgaaag ggtcgctgcc gtcggcggcg cgcgccagcg cctggaccgc gatctcaccg
     3481 ccacaggccg cctccgcacg cagcccggcc gcctgcaggg tcgcgcacag gaagtcgccg
     3541 aaggccgcgc tcgcgctcgc caccagcacc cgcgccccgg cgagcacgcc ggcacgcagg
     3601 ggcgccggat cggcgaccag gcgcagcggc agcaccacct cgaagcggct gcccgcgtcc
     3661 ggcacgctgt cgacgccgat ccgcccgccc atgagctcgc tgagctggcg gcagatcgcc
     3721 agcccgaggc cggtaccgcc gtacttgcgc gtggtcgagt tgtccgcctg cgaaaaggcg
     3781 ccgaagatcg cctcgagctt gtccggcgcg atgccgcagc cggtgtcgcg caccaggaac
     3841 tcgaggctgg ccatgctgcc gttgcgctcg atacagcgca cgcgcacctc gacctcgccg
     3901 cggtcggtga acttgatcgc gttgccgatg aggttcacca ggatctggcg caggcgcgta
     3961 gggtcgccgc gcagcaccga gggcacgtcg gcaccgatgt cgtagtagag ctccagcccc
     4021 ttctgcgccg cacgcagcgc gagcgcacga caggtctcgg agacgaccga ctgcagggag
     4081 aagtcgatct gctcgacgct caggcggccg gcctcgatgc gcgagaagtc gaggatgtcg
     4141 ttgatgatgg tcagcagcgc ctcggccgag gacttcaccg tctgcaggta ttcgcgctgc
     4201 tcgcccgcga tcggggagtc gagcagcaga tcggtcatgc cgatgatgcc gttcatcggc
     4261 gtgcggatct cgtggctcat gttggcgagg aagtcgccct tggcccggct cgccgcctcg
     4321 gccgcttcct tggcctcgag gagctcgatc tcgcgcagct tgcgctcggt cacgtcacga
     4381 taggtgccct cgacccgcga ccaccgccca tcctcgccgc gtccgccggc gttgccgcac
     4441 acctcgatcc agtgccagct gccgtcctgc gcgcggatgc ggatctcggc acgcaattcg
     4501 tccgcgtcgc cgcccaggtg ggcacgcagg gcttgctgca gcgcggacct gccctcctcg
     4561 tccacgagcg ccatccagtc ggtggcctcg gtgccttcgt agccgagcag cctgcgccaa
     4621 cgctcgtcga ggcggatcgc gccgctcgcg aggtccttgt gccacacacc ggcaccggcg
     4681 ttcgccgaga ccaggtcgag gtgtcgacgc gcgctcgaca aggcgcgcag cgcggcatcg
     4741 cgctcccccc gcaggcgggc gagctccgct tcgacggaag caggtccaga aggattcccg
     4801 cgcgtgtcgg gcgcgccgct catggcgtga ctcagcgcag gccgagcacg tcctgcatgt
     4861 cgtagaggcc ctgcgcacga ccggcgagga agcgcgccgc ccgcatcgaa ccgagcgcgt
     4921 agggcatgcg gctgcccgac ttgtgggtga tctcgatgcg ctcgccgatg ccggcgaaga
     4981 gcacggtgtg gtcgccgacg acgtcgccgc cacggatggt cgagaagccg atggtctcgg
     5041 cgctgcgctc gccggtgtga ccctcgcgac cgtagatcgc gcaggtctcg aggtcgcggc
     5101 cgagctcgcg ggcgacgacc tcgcccatgc gcagcgcggt gcccgagggc gcatcgacct
     5161 tgaagcgatg gtgcgcctcg atgacctcga cgtcgtagcc ctccgcgagg atgcgcgcgg
     5221 cgacctcgag cagacggaac accgcgttca cgcccaccgc catgttgggc gcgaacacca
     5281 ccgggacgtg ctcggcggcg gcggcgatcg cggccttgcc ggtggcgtcg aagccggtgg
     5341 tgccgatcac catcgccttg ccggcggcgc gcgcgagcgc gaggtgcgcg agcgtgccct
     5401 cggggcgggt gaagtcgatc acgcaatcgg ccgcggcgat cgcagcggcg gcatcgtcgg
     5461 tgatgagcac gccggttgcc accccggcca tctcaccggc atcgcggccg atgaagggag
     5521 tgtcgctgcg gtcgaaggcg gcggcgagca cgacgccctc ctccttcagc gcggcctcga
     5581 tcagcattct gcccatgcgc ccggacgcac cggcgatcgc gactcgaatc tgggacatcg
     5641 gattggtttc ctgcatcaat gggcccgcgc agacggccgg cccggaatgg gtctgagcgc
     5701 cgcctcagcg gcccgcagcg ggcgggatct cgaccacgcg cgagcgctgc tgcggcaccg
     5761 cttcgggcgc ggcggaagcc gctgcgacgt caccctcgat gcggtcgagc acgtcgcccg
     5821 cgaagaagag cgagatcacg cgctgctgtg cttcaccgct gcccggacgg aagcgataga
     5881 catagtccca gcgatccgag cggaacatgt cgaccaccag cggcgaaccc agcacatagc
     5941 gcacctgttc gcgggtcatg ccgcggcgca actgcgcgac catctcctga tcgacgtagt
     6001 tgccctggcg gacgtcgatc cggtaggggt cgacgaggcc gaccacggag tcgaaggagc
     6061 agcccgagat caggccggag gagacgacga gcgcagcgag gaaggaacgc atgggagagg
     6121 gggcgccggg atgcgaccgg ggtcgcagtt ctcagttagg ggcaaaaaat ataacatagc
     6181 cgcgatcgac ggcgctcgaa cgccattgcc gcccggatgc cgaagatcct cctgccgacc
     6241 gcgaaccatg ccgtttcgcc gcggtctggt tctccggaga ccgcgcggcc acccgccgga
     6301 cacgcagcct tcgcgtgctc ccgcaacccg atcttccgca agccaacttc acccagagcc
     6361 catgtccgac aactccagga acctgaaaag catcggcctg aaggcgacct atccccgcct
     6421 aaagatcctc gacctcttcc agagctcgga gcagcgccac ctgaccgcgg aagacgtgta
     6481 ccgcacgttg atgaacgaag gcatggacat cggcctggcg acggtctacc gcgtgctcac
     6541 gcagttcgaa caggccggtt tgctcgagcg ccattacttc gagtcgggca aggcggtctt
     6601 cgaactcaac gagggcggcc atcacgacca cctcgtgtgc atgcagtgcg gcaaggtgga
     6661 agagttcttc gacgccgaga tcgagcgccg ccagaaccag atcgccaccg agcgcggctt
     6721 cgcgatccgc gagcacgcgc tctacatcta cgccgactgc cagcgcgaga actgcccgaa
     6781 cctggagcgg gagaaggact gaatcagcgc cggccgagca tctcggctgc atgctcgcgc
     6841 gtggtcgcgg tgatattcac gccgccgagc atgcgcgcga tctcctccac ccgcgtcgca
     6901 tcgtcgagcg gcgtgacctc gctcagcgtc tctccaccct ggtcgcgctt ggcgatgcgc
     6961 cactgccagt cggcgcaggc cgccacctgg gggaggtggg tgacgcacag cacctggcga
     7021 tcccgcccga gacgggcgag cagcttgccg acgatctcgg ccacgcggcc gccgatcccc
     7081 acgtcgacct cgtcgaagat cagcgtcggc accgcgctgt cgcggctggt gatgacctgg
     7141 atcgccagcc cgatgcgcga cagctcgccg cccgaggcca ccttggcgag gctgcgcagc
     7201 ggctggcccg cgttcgcggc gacgcgaaac tccaccgcct ccacgcctga cgcggagggg
     7261 ctgcaaggct cgagcgcgac ctcgaagcgt ccgcctgcca tcgccaggtc ctgcatcgcg
     7321 gcggcaatct cctccgagag ccggcgcgcc gcggggatgc gcgccgcggt cagcttcgcc
     7381 gccgcggcgt cgtaggccgc ctgcgccgcc tgcgccgccg cggccaggcg cgccgggtcg
     7441 gcggtcgcct cgagggtgtc gagccgctcg cgccactgct gcccgagcgc gggcagctcc
     7501 tcgggctgta cgcggtactt gcgcgccgcc tccatcaccg cggcgatgcg gcgctcgagc
     7561 tcggcaagac gtccgggatc gaggtcgagc cggtcgcgat agcggcgcag cgcatgcagg
     7621 gcctcgtcgg cctggatcgc ggccgcagag atgagctcgc gcacgtccgc cagcccggcg
     7681 tcgaagtcgg ccagcgcggc gacgcggccg tcgagccggc cgagcaccga gcacaccgag
     7741 agctcgccct cgccgagcgc gaccaccgcc tcctccgccc cctcgatcag gctcgcggcg
     7801 tgcgccaggc gtccatgctc ggcgttgagc tccgcccatt cgtcgctgtc gaagccgacc
     7861 tgctcgagct cgcgcagctg ccacgccagc agctcgcgct cacgcgccga gctcgccgaa
     7921 tcggcctcgg cctcgcgttg caggcgcagc aggcgctgcc actcgcggtg gcgcgcggcc
     7981 acctcggcga ccagcgcgcc cgcgcccgcc tgggcgtcga gcaggtcgcg ctgcgcgtcg
     8041 gcgcgcagca gcgcgtggtg ggcgtgctgg ccgtggatgt cggcgagcca ctcgcccgcg
     8101 gcgcgcagct gcgcaagcgt ggccgccacg ccgttgatcc acgcccggct gcgcccgccg
     8161 gcatcgatcg tgcggcgcag gatcagcacg ccctcgtcgg cgggcagcgc ctgctcggcg
     8221 agccacgcga ccagcccctc ggccgcaggc aggtcgaact ctgcggcgac gtcggcacgg
     8281 tcgcggccgc tgcgcaccat cgccgcctcg ccgcgcccgc cgagggcgag cccgagcgcg
     8341 tcgagcagga tggacttgcc ggcgccggtc tccccggtca gcgcaccgaa gccggtggcg
     8401 aactcgaggt cgaggcgatc gacgatgacg aagtcacgga tggtgaggca gcggagcatg
     8461 gcagcggcgg tcgcggatcg ggacggcgga cggttcgggg gtggaggtca ggcggcgggc
     8521 gctcacaccc tcggcgccgc gctccagtgc agcttctggc gcagcatcgc gaagtaggag
     8581 tagcccttgg gatgcagcag gcgcaggctg cggctcgagc gcgtcagccg cacgcagtcg
     8641 cctgcgcgca ggtcgaagcg ggtctggccg tcgaagtgca cccgggcgtc gtgcggcggc
     8701 agcagcgcga tatcgatgcg gcaggagtcg ggcagcgtga tcgggcgcgc ggtgagcgcg
     8761 tgcgggcaca gcggcacgag cgcgatcccg cccacgctcg ggtgcaggat cggaccgttg
     8821 gccgagagcg cgtaggcggt ggagccggtg ggggtggaaa cgatcatgcc gtccgagcgc
     8881 tgcgtgtaga cgaactcctc gtcgatcgac agctcgaact cgatcatgcg cccgagctcg
     8941 cccttgttca ccaccacgtc gttgagcgcc agcgtgtgga acacgcgcgc gccgccacgc
     9001 agcacc
//
LOCUS       DAOTIN010000127         8962 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_9308_length_8962_cov_8.951499, whole genome shotgun sequence.
ACCESSION   DAOTIN010000127 DAOTIN010000000
VERSION     DAOTIN010000127.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 8962)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 8962)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8962
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_9308_length_8962_cov_8.951499"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..910
                     /locus_tag="P5537_14280"
     CDS             <1..910
                     /locus_tag="P5537_14280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="TrpB-like pyridoxal phosphate-dependent enzyme"
                     /protein_id="HRV79253.1"
                     /translation="EVRIYMVKVSYDQKPYRRLMMQTWGGEVFASPSPHTETGRRLLA
                     EDSNNPGSLGIAISEAVEEAAGRADTNYTLGSVLNHVVLHQSIIGLEAKKQLDKVGLY
                     PDVVIGPCGGGSSFAGIAFPFLADKAAGDKRADKLRCVAVEPSSCPTLTKGQYAYDYG
                     DASGFTPLMKMYTLGHDFMPPGIHAGGLRYHGDSPLVSNLLHAGLIEAAAVPQLATFD
                     AGVQFARAEGIIPAPESCHAIRQAIDEALACKASGEAKTILFNLTGHGHFDMSSYERY
                     FSGKLEDFDYPADAVAASLAHLPKVG"
     gene            972..1889
                     /locus_tag="P5537_14285"
     CDS             972..1889
                     /locus_tag="P5537_14285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HRV79254.1"
                     /translation="MTILRLLLILLLILNALAFAAIGGWLGGEPATGEAARIATQLHP
                     ERIRLANETGATGLAPVAAEPSLSSAVVTRAASAPDTPAPATADAATEDAPAPSTAQD
                     ATLPAARVDAESSPLPAPEIAPPVEPAPAEPAPTEPAPAEPPPAEPAVVPAPSPAPPA
                     LCHAWADLSASEADRLVQRLRRIGITAARSRSETPEAWWVRIPPQRNRGEAERRVVEL
                     NLLGVSDTFIVQESGPNQNAVSLGLFKTENRARILLGQLRAKGVENAGIEPRMSTSYR
                     IQANVPANELRIVESAAPGLRAKRQACTR"
     gene            1903..2517
                     /gene="coaE"
                     /locus_tag="P5537_14290"
     CDS             1903..2517
                     /gene="coaE"
                     /locus_tag="P5537_14290"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326473.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HRV79255.1"
                     /translation="MSVKRPYIVGLTGGIGSGKSAATDRFAALGASVVDTDRIAHELT
                     APGGGAIEAIHTAFGDAMIAPDGSLDRTAMRALAFREPDARRRLEAILHPMIRAESAR
                     QCVAAGGPYVILAVPLLVESGGYRERCDRICVVDCPEALQLERVRARNGLADEQIRAI
                     MAAQASRAQRLAAADDVIDNAGTLASLHAQVDRLHAAYLAATTH"
     gene            2603..3358
                     /gene="zapD"
                     /locus_tag="P5537_14295"
     CDS             2603..3358
                     /gene="zapD"
                     /locus_tag="P5537_14295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004381200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapD"
                     /protein_id="HRV79256.1"
                     /translation="MISYEYPLNERIRTLLRLEDLFLKIAHFTAGAAPQDHHVALLTI
                     FETLEVASRADLKVDLVQELERQRQILMSFRNNPEISEEALAGALYEIEQASTGLLAM
                     AGKIGHYLRENEWLMSIRSRAAIPGGVCQFDLPSYHYWLNRDPAVRRGDLGTWIQPMA
                     PIRDGIEIVLRLLRASGHPEPLHARAGAFQLTMAGRTAQMLRVRLAQSETVVPEISAN
                     KYALNVRFMLPETVARPRVAERDVAFELTFCSL"
     gene            3361..3582
                     /locus_tag="P5537_14300"
     CDS             3361..3582
                     /locus_tag="P5537_14300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor YacG"
                     /protein_id="HRV79257.1"
                     /translation="MSTRVRTVRCPTCGKDVEWKPESRWRPFCSARCKQIDLGEWASE
                     GYRVPSSPPDAPLDEIDYQPPGAGEIRRR"
     gene            complement(3623..4573)
                     /locus_tag="P5537_14305"
     CDS             complement(3623..4573)
                     /locus_tag="P5537_14305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004381204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008413 - 8-oxo-7,8-dihydroguanosine
                     triphosphate pyrophosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nudix family hydrolase"
                     /protein_id="HRV79258.1"
                     /translation="MTRKRVEVAAGVLLREDGCYLLGQRAPDTVYAGYWEFPGGKVEP
                     GESPAQALIRELDEELGIRVTRLRPWLCREHLYEHAHVRLHFHEVVAWEGELADRVHS
                     ALAWVRPEGPAREPMLPANGPILKALRLPRTMAITHAAEIGVDAQLEALERALAAGLR
                     LVQVREGALPEDAREDFARAVLARVRAHGGLLLVNGDEALARRIGADGVHLPARRLMA
                     AQGRPDFPWVGASCHDRTELERAAALELDYALLGPVLPTLTHPGQAGMGWEGFAATAA
                     GLPLPVFALGGLAADDMERARDAGAHGIAAIRAIWRTARE"
     gene            complement(4570..5445)
                     /locus_tag="P5537_14310"
     CDS             complement(4570..5445)
                     /locus_tag="P5537_14310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HRV79259.1"
                     /translation="MTKELADLLARAEGVLARLETLLPGPAAAPDWDAALAFRWQRRH
                     GRAELRPVRAPHRITLADIQDVDDQKARIDRNTRQFLAGRRANNVLLTGARGTGKSSL
                     VKALLTEYAARGLRLIEVDKTDLVDLPEIVELIAGRPERFILFCDDLSFEEGEDAYKA
                     LKSVLDGSVSAMSDNVLIYATSNRRHLMPEYHDENLQARHVDGELHPGEAVEEKISLS
                     ERFGLWISFYPFSQDEYLDIVAHWLRSFGASEDEIASSRQEALQWALMRGSRSGRVAW
                     QFARDHAGRLLDDAR"
     gene            complement(5426..5560)
                     /locus_tag="P5537_14315"
     CDS             complement(5426..5560)
                     /locus_tag="P5537_14315"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79260.1"
                     /translation="MWLIFLELGVALALLLVVGLALRQPSAPACDRDDCGNPDDQGTR
                     "
     gene            5625..6881
                     /locus_tag="P5537_14320"
     CDS             5625..6881
                     /locus_tag="P5537_14320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase A"
                     /protein_id="HRV79261.1"
                     /translation="MPRKMFRRTRSTLLPSLPALLLAACAALPGTPEPSGERACVPCP
                     SCPPCPGAPSVAAPGAPAAPAAPAAAAPQASDWSAIEGWQRDELSAAWPALRASCSTL
                     VRQAQWKTVCDEAARLGGAPDGGTVRRFFESRFTPWQLVNADGSANGLVTGYYEPLIR
                     GSRSRNARSPWPIHGVPQDMLTIELADVYPELKSLRLRGRLVGNKVLPYWNRQQLAER
                     QVPAPVLLWADDPIELFFLQVQGSGRVQLPDGSLVRIGYADQNGHPYQSIGRWLVAQG
                     ELTLDKASMDGIKRWAQDNPQRLQELLNANPSYVFFREMPASGGGPVGALGVPLSEGR
                     SIAVDPRYVPLGAPVFLATTQPLSERPLERLVMAQDTGGAIKGAVRADFFWGFGTEAG
                     REAGKMRQQGRMWVLLPKGMKPPVPR"
     gene            complement(6930..7658)
                     /locus_tag="P5537_14325"
     CDS             complement(6930..7658)
                     /locus_tag="P5537_14325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004327259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbC family protein"
                     /protein_id="HRV79262.1"
                     /translation="MMNVSVPSLIRPLGLALALCAATLAHADEAEVKKSMEAFIGAPA
                     VEKVTRTDYAGLYEVVLKNGQLVYTDAKNSFIIDGSIIDTASRRDVTQARLNQLSAID
                     FSTLPLDQAVKVVKGKGTRVIATFEDPNCGYCKRLGKDLAQMEDVTVYTFLYPILSED
                     SRNKSDNIWCAKDKGKAWTDWVVDGKEPAKASCDTATIARNVELGQSLRISGTPTIFL
                     ADGSRIGGYLPKAELEKAIDAAKR"
     gene            complement(7673..8836)
                     /locus_tag="P5537_14330"
     CDS             complement(7673..8836)
                     /locus_tag="P5537_14330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004327260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiH/UbiF family hydroxylase"
                     /protein_id="HRV79263.1"
                     /translation="MKFDLIIVGGGLAGAALAVALRRSALRIAVVEHAAPRRPTGWDA
                     RIYAYSPASARFLDELGVWAHLDHDRLGPVFEMRIHGDAGGELVFSAYDSGLEELAWI
                     GESSLVHVEIWESLKRQHNVTLFCPATPAALEIDADVATLRLDDGRSLQAALVIGADG
                     RDSWVRERAGIEATVKPYGERGVVANFVCERPNHGVAFQWFRADGVLAWLPLPGRTMS
                     MVWSAPDALADELLALDPEPFCARVEAAGGRALGKLELAGQRAAFPLRLMRVEEVVRP
                     RVALIGDAAHAIHPLSGHGINLGFQDAKALAEVLAALPSWRDAGELSVLRRYARMRAE
                     EPFLLQYTTHALSRLFGRQDPLLSSLRNVGMNLTGQLPVLKNALVRYAANGRF"
BASE COUNT         1361 a         3321 c         3022 g         1258 t
ORIGIN      
        1 ggaggtgcgc atctacatgg tcaaggtgag ctacgaccag aagccctacc gtcgcctgat
       61 gatgcagacc tggggcggag aggtcttcgc cagcccctcg ccgcacaccg agaccggccg
      121 ccgcctgctc gccgaggact cgaacaaccc cggctcgctc gggatcgcca tctccgaggc
      181 agtggaagag gccgccggcc gcgccgacac caactacacc ctcggctcgg tgctcaacca
      241 cgtggtgctg caccagagca tcatcggcct ggaagcaaag aagcagctcg acaaggtcgg
      301 cctttacccc gacgtcgtca tcggcccctg cggcggcggc tccagcttcg ccggcatcgc
      361 cttccccttc ctcgccgaca aggccgcggg cgacaagcgc gccgacaagc tgcgctgcgt
      421 ggcggtggag ccgagctcct gcccgacgct gaccaagggg cagtacgcct acgactacgg
      481 cgacgcctcc ggcttcaccc cgctgatgaa gatgtatacg ctgggccacg acttcatgcc
      541 gcccggcatc cacgccggcg gactgcgcta ccatggcgac tcgccgctgg tgtcgaacct
      601 gctgcacgcc ggcctcatcg aggccgccgc cgtgccgcag ctggcgacct tcgatgcggg
      661 cgtgcagttc gcgcgtgccg agggcatcat cccggcgccc gagtcctgcc acgcgatccg
      721 ccaggccatc gacgaggcgc tggcctgcaa ggcgagcggc gaggccaaga ccatcctgtt
      781 caacctcacc ggccacggcc acttcgacat gagttcgtac gagcgctatt tctcgggcaa
      841 gctcgaggac ttcgactatc cggccgatgc ggtggcggcc tcgctcgccc acctgcccaa
      901 ggtcggctga gcgacccgcg gccgccggct cgtccggcgg cctcactgac ccccctggca
      961 cgcgcctcgg catgacgatc ctgcgcctcc tgctcatcct gctgctgatc ctcaacgccc
     1021 tcgccttcgc ggcgatcggc ggctggctgg gtggcgagcc ggcgacgggc gaggcggcgc
     1081 gcatcgccac ccagctgcac ccggaacgca tccgcctggc gaacgagacc ggtgccaccg
     1141 gactcgcgcc cgtcgctgcc gagccgtcct tgtcctccgc agtcgtcacc cgcgcagcct
     1201 ccgcgccgga taccccggca cccgcgacag cggacgccgc gacggaagac gcccccgccc
     1261 cgtccaccgc acaggacgcc acgctgcccg cggcccgcgt cgacgccgag tcgtccccac
     1321 tcccggcgcc cgagatcgcg cccccggtcg agcctgcccc tgccgagccc gcccccaccg
     1381 agcctgcccc tgccgagccc ccacccgccg agccggccgt ggttcccgcc ccctcgccgg
     1441 cgccgcccgc actctgccat gcgtgggccg acctcagcgc cagcgaggcc gaccgcctcg
     1501 tccagcgcct gcgccgcatc ggcatcaccg cggcgcgcag ccgcagcgag acgcccgagg
     1561 cctggtgggt gcgcatcccg ccgcaacgca accgcggcga ggccgagcgt cgcgtcgtcg
     1621 aactcaacct gctcggcgtc agcgacacct tcatcgttca ggagtccggc cccaaccaga
     1681 acgcggtctc gctcggcctc ttcaagaccg agaaccgcgc ccgcatcctg ctcggccagc
     1741 tacgcgccaa gggcgtcgag aatgcgggca tcgagccgcg catgagcacg agctaccgca
     1801 tccaggccaa cgtcccggcc aacgagctgc gcatcgtcga gtcggccgcg cccgggctgc
     1861 gcgccaagcg ccaggcctgc acgcgctgaa gcggagaagg gcatgagcgt gaagcgtccc
     1921 tacatcgtcg gcctcaccgg cggcatcggt agcggcaaga gcgccgccac cgaccgcttc
     1981 gccgcgctcg gcgcgagcgt ggtcgacacc gaccgcatcg cccacgaact caccgccccc
     2041 gggggcggcg ccatcgaggc catccacaca gccttcggcg acgccatgat cgctccagac
     2101 ggcagcctcg accgcaccgc gatgcgcgcg ctcgccttcc gcgagccgga tgcgcgccgc
     2161 cgcctcgagg ccatcctgca cccgatgatc cgcgccgaga gcgcccgcca gtgcgtggca
     2221 gccggcggcc cctacgtgat cctcgccgta cccttgctgg tggagtcggg cggctaccgc
     2281 gagcgctgcg accgcatctg cgtggtcgac tgccccgagg cgctgcagct cgagcgcgtg
     2341 cgcgcgcgca acggcctcgc cgacgaacag atccgcgcca tcatggccgc acaggccagc
     2401 cgagcgcagc gcctggccgc tgccgacgac gtgatcgaca acgccggcac gctcgcctcc
     2461 ctgcacgcgc aggtcgatcg cctgcacgcc gcctacctcg ccgccacgac gcactgaaac
     2521 cgtgcctcgc cgtggcggca agggggcctg tgctatcatc ggcgcgaatc agaacaggtg
     2581 cgatacaggc ggacacgctg cggtgattag ctacgaatat cctctcaacg agcgcatccg
     2641 caccctgttg cgcctggagg acctgttcct caagatcgcc catttcaccg caggcgccgc
     2701 gccgcaggat caccacgtcg cgctgctgac catcttcgag acgctcgagg tcgccagccg
     2761 cgccgacctc aaggtcgacc tggtgcagga acttgagcgc cagcgtcaga tcctgatgtc
     2821 cttccgcaac aaccccgaga tctccgaaga ggcgctcgcg ggcgcgctct acgagatcga
     2881 gcaggcctcc accgggctgc tcgcgatggc ggggaagatc ggccactacc tgcgcgagaa
     2941 cgagtggctg atgagcatcc gcagccgcgc ggcgatcccc ggcggggtgt gccagttcga
     3001 cctgccctcc taccactact ggctcaaccg cgacccggcc gtgcgccgcg gcgacctcgg
     3061 cacctggatc cagccgatgg cgccgatccg cgacggcatc gagatcgtgc tgcgcctgct
     3121 tcgcgccagc ggccaccccg agccgctgca tgcgcgcgcc ggcgccttcc agctgaccat
     3181 ggcgggacgc accgcgcaga tgctgcgcgt gcgcctggcg cagtccgaga ccgtggtgcc
     3241 cgagatcagc gccaacaagt acgcgctcaa cgtgcgcttc atgctgcccg agaccgtcgc
     3301 gcgcccgcgc gtcgccgagc gcgacgtcgc cttcgagctc accttctgca gcctgtgaac
     3361 atgagcaccc gcgtccgcac cgtgcgctgc cccacctgcg gcaaggacgt cgagtggaag
     3421 ccggagagcc gctggcggcc gttctgctcg gcgcgctgca agcagatcga tctcggcgag
     3481 tgggcctcgg aaggctaccg cgtgccgagc tcaccgcccg acgcaccgct cgacgagatc
     3541 gactatcagc cgcccggcgc gggcgagatt cggcgacgct gaacggcgca gctccgcgcc
     3601 ccctcacgcg gcaagcacgc gctcactccc gggcggttct ccagatcgcg cggatcgcgg
     3661 cgatgccgtg cgcgccggcg tcgcgcgcgc gctccatgtc gtccgccgcc agcccgccga
     3721 gcgcgaatac cggcagcggc aggcccgccg ccgtggcggc gaacccttcc cagcccatgc
     3781 cggcctgccc gggatgggtc agggtcggca gcaccggtcc gagcagggcg tagtcgagtt
     3841 ccagcgccgc ggcacgctcg agctccgtgc gatcgtgaca ggacgccccc acccagggga
     3901 aatccggtcg tccctgcgcc gccatcaggc gacgcgccgg cagatgcacg ccgtcggcac
     3961 cgatgcggcg cgcaagcgcc tcgtccccat tcaccagcag caggccgcca tgtgcgcgca
     4021 cacgcgccag caccgcgcgc gcgaagtcct cgcgcgcatc ttcgggcagc gcgccctcac
     4081 gcacctgcac caggcgcagg ccggcggcga gcgcgcgctc cagggcctcg agctgggcgt
     4141 cgacgccgat ctccgcggcg tgggtgatgg ccatcgtgcg cggcaggcgc aaggccttca
     4201 ggatcggtcc gttggcgggc agcatcggct cgcgcgcggg gccctcggga cgcacccagg
     4261 cgagcgcgct gtgcacccgg tcggcgagct cgccctccca ggccaccacc tcgtggaagt
     4321 gcaggcgcac atgggcgtgc tcgtagaggt gctcgcggca cagccagggc cgcagccggg
     4381 tgacgcggat gccgagctcc tcgtcgagct cgcggatcag cgcctgcgcc gggctctcgc
     4441 cgggctcgac cttgccgccg ggaaactccc agtagcccgc atacacagta tcgggcgcgc
     4501 gctggccgag caggtagcaa ccgtcctcgc gcagcagcac gccagcggcg acctccaccc
     4561 gcttgcgcgt catcgtgcgt cgtccagcag gcggccggcg tggtcgcggg cgaactgcca
     4621 ggcgacgcgg cccgagcgcg agccccgcat cagcgcccac tgcagcgcct cctggcggga
     4681 cgaggcaatt tcgtcttcgc ttgcgccgaa gctgcgcagc cagtgtgcga cgatgtcgag
     4741 gtactcgtcc tggctgaagg ggtagaagga gatccacagg ccgaagcgct cggacagcga
     4801 gatcttctcc tccaccgcct cgcccgggtg cagctcgcca tcgacgtggc gggcctgcag
     4861 gttctcgtcg tggtactccg gcatgaggtg gcggcggttg gaggtggcgt agatcagtac
     4921 gttgtccgac atcgccgaca ccgagccgtc gagcacgctc ttcaaggcct tgtaggcgtc
     4981 ctcaccctcc tcgaaggaga gatcgtcgca gaacaggatg aagcgctccg gccggccggc
     5041 gatcagctcg acgatctcgg gcaggtcgac cagatcggtc ttgtcgacct cgatcaggcg
     5101 caggccacgc gcagcgtatt cggtgagcag ggccttgacc agcgaggact tgccggtgcc
     5161 gcgcgcgccg gtgaggagca cgttgttggc acgccggccg gcgaggaact ggcgggtgtt
     5221 gcggtcgatg cgcgccttct ggtcatccac gtcctggata tcggcgagcg tgatgcggtg
     5281 cggcgcgcgc acgggacgca gctcggcgcg gccgtggcgg cgctgccagc ggaaggcgag
     5341 cgcagcgtcc cagtcgggcg cggcggcggg gccgggcagc agggtttcga ggcgtgccag
     5401 caccccttcg gcgcgggcga gcaggtcagc gagttccttg gtcatcgggg tttccgcaat
     5461 cgtcccggtc gcaagcgggc gcggacggct ggcgcagggc gagcccgacg accaggagca
     5521 gcgcgagcgc gacgccgagt tctagaaaga tcagccacac cgtccgtctc cggcagtccg
     5581 tgggggcccg gtatactggc ggcaaagaca gccgagttca accgatgccc cgcaagatgt
     5641 tccgccgcac ccgcagcacc ctcctgccct ccctccctgc cttgctgctg gccgcctgcg
     5701 ccgccctgcc gggcacgccc gaaccctcgg gcgagcgcgc ctgcgtcccc tgcccgagtt
     5761 gcccgccttg ccccggcgcg ccgtcggttg ctgcgccggg cgcccccgca gccccggccg
     5821 cccctgctgc cgccgcaccg caggcgagcg actggagcgc gatcgagggc tggcagcgtg
     5881 acgaactgtc ggcggcctgg ccggcgctgc gcgcgtcctg ctccaccctg gtgcggcagg
     5941 cgcaatggaa gacggtgtgc gacgaggccg cgcgcctggg tggcgcgccc gacggcggca
     6001 cggtgcgccg cttcttcgag agccgcttca cgccatggca gctggtcaat gccgacggca
     6061 gcgcgaacgg cctggtcacc ggctactacg agccactgat ccgcggcagc cgcagccgca
     6121 acgcgcgcag cccctggccg atccacggcg tgccgcagga catgctgacg atcgagctcg
     6181 ccgacgtgta tcccgaactg aagagcctgc gcctgcgcgg ccgtctggtc ggcaacaagg
     6241 tgctgccgta ctggaatcgc cagcagctcg ccgaacgcca ggtccccgcc ccggtactgc
     6301 tatgggcgga cgacccgatc gagctcttct tcctccaggt acagggttcg gggcgcgtgc
     6361 agcttcccga cggcagcctg gtgcggatcg gctacgccga ccagaacggc cacccctacc
     6421 agtcgatcgg acgctggctg gtcgcccagg gcgagctgac gctggacaag gcctcgatgg
     6481 atggaatcaa gcgctgggcg caggacaacc cgcagcgcct gcaggagctg ctcaacgcca
     6541 acccgagcta cgtgttcttc cgcgagatgc cggcctcggg cggcggaccg gtcggggcgc
     6601 tcggcgtgcc gctgtccgag ggacgcagca ttgcggtgga tccgcgctac gtcccgctgg
     6661 gggcgccggt tttcctggcg acgacgcagc cgctgagcga gcggccgctc gagcgcctgg
     6721 tgatggcgca ggacaccggg ggtgcgatca agggtgcggt gcgcgcggac ttcttctggg
     6781 gcttcggcac ggaagccggc cgcgaggcgg gcaagatgcg ccagcagggg cggatgtggg
     6841 tgctgttgcc gaaaggcatg aagccgcccg tgccgcgctg atgcgcaccg cggcgcgggc
     6901 gcatatgccc gcccgcggta ggcagacggt caacgcttgg cggcgtcgat cgccttctcg
     6961 agctcggctt tcggcaggta gccgccgata cgcgaaccgt cggcaaggaa gatcgtcggc
     7021 gtgccgctga tgcgcaggct ctggccgagt tcgacgttgc gcgcgatggt cgcggtgtcg
     7081 cagctcgcct tcgccggctc cttgccgtcg accacccagt cggtccacgc cttgcccttg
     7141 tccttcgcgc accagatgtt gtcggatttg ttgcgagaat cctcgctcag gatcggatag
     7201 aggaaggtgt agacggtgac gtcttccatc tgcgcgagat ccttgccaag gcgcttgcag
     7261 tagccgcagt tgggatcctc gaaggtggcg atcacgcgcg tacccttgcc cttgaccacc
     7321 ttcaccgcct ggtcgagcgg gagggtcgag aaatcgatcg cggagagctg gttcaggcgc
     7381 gcctgggtca cgtcacgacg gcttgcggtg tcgatgatgc tgccgtcgat gatgaagctg
     7441 ttcttggcgt cggtatagac gagctggccg ttcttcagca cgacctcgta cagcccggcg
     7501 tagtcggtgc gcgtgacctt ctccaccgcc ggcgcgccga tgaaggcctc catgctcttc
     7561 ttgacctcgg cttcgtccgc gtgcgcgagc gtggccgcgc agagcgccag ggcgaggccg
     7621 agcggccgga tcagggatgg gacggaaaca ttcatcaggt tctccacagg attcagaaac
     7681 ggccgttggc cgcgtagcgc acaagcgcgt tctttaagac cggaagctgc ccggtcaggt
     7741 tcattccgac gttgcgcagc gacgacagca aggggtcttg gcgcccgaac agtcggctca
     7801 acgcgtgggt ggtgtattgg agcaaaaagg gctcctcggc gcgcatgcgg gcgtaacgcc
     7861 gcagcaccga aagctctccc gcatcccgcc aggaaggcag cgccgcgagg acctccgcca
     7921 gcgccttcgc atcctggaag ccgaggttga tcccgtgccc cgagagcggg tggatcgcgt
     7981 gcgcggcatc gccgatcagc gcgacgcgcg gacgcaccac ctcttccacc cgcatcaggc
     8041 gcagcgggaa cgccgcgcgc tgcccggcga gctcgagctt gccgagtgcc ctcccgccgg
     8101 cggcctccac gcgcgcgcag aagggctccg ggtcgagcgc gagcaactcg tcggcgaggg
     8161 cgtcgggcgc cgaccacacc atcgacatgg tgcgcccggg caggggcagc caggcgagca
     8221 caccgtcggc gcggaaccac tggaaggcca ccccgtgatt ggggcgctcg cagacgaagt
     8281 tcgccaccac accgcgctcg ccgtaaggct tgaccgtggc ctcgatcccg gcacgttcgc
     8341 gcacccagga gtcgcgcccg tccgcaccga tcaccagcgc ggcctgcagg ctgcggccgt
     8401 cgtcgaggcg cagcgtagcc acgtccgcat cgatctccag cgcagccggc gtcgccgggc
     8461 agaacagcgt gacgttgtgc tggcgcttga ggctctccca gatctccacg tgcaccaggc
     8521 tggactcgcc gatccaggcc agctcctcga ggccgctgtc gtaggccgag aacacgagct
     8581 ctccaccggc gtcgccgtga atacgcatct cgaagaccgg gccgagtcgg tcatggtcga
     8641 gatgcgccca cacaccgagt tcgtcgagga agcgcgcgct cgccggacta taggcgtaga
     8701 tgcgcgcatc ccagcccgtg ggacgacgcg gcgcggcatg ctcgaccacg gcgatgcgca
     8761 gcgcactgcg ccgcagcgcc accgccagcg ccgcaccggc gaggccgccg ccgacgatga
     8821 tgagatcgaa tttcatgacc attcccgaca cttcagcaca gcccggaatt gtgcccgagg
     8881 gcgcacctcg ccgtcacgcc tgccatgcgt gtcttgctgc gtacccgtgt ctgggggcgt
     8941 ctcgggcgtg gattggttcg ca
//
LOCUS       DAOTIN010000128         8920 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_9356_length_8920_cov_8.559955, whole genome shotgun sequence.
ACCESSION   DAOTIN010000128 DAOTIN010000000
VERSION     DAOTIN010000128.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 8920)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 8920)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8920
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_9356_length_8920_cov_8.559955"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..846)
                     /locus_tag="P5537_14335"
     CDS             complement(<1..846)
                     /locus_tag="P5537_14335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004384132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HRV79264.1"
                     /translation="MKKNLWLLAIAQGLFLTNNVVFIAINGLVGFSLAPVGWMATLPV
                     MGYVVGGALSTGLVARSQRRWGRQVSFQLGLLVAFLTALLCAFALSIGSFWLLVAGTV
                     IAGYYSANGQLYRFAAGELAPPSFREKAVSLVLAGGLIGAVIGPNLANHTREALGAPF
                     LGSYLALAVVALVSMAVMAGIRFPSEPAKKPGADGGRALGEIVRQPVFIVSALAAAMS
                     YGVMNLLMAATPLAMDVCGMPFSDAALVLEWHVIGMFAPGFFTGHLIKRFGVLQVMGA
                     GVALNF"
     gene            1725..2048
                     /locus_tag="P5537_14340"
     CDS             1725..2048
                     /locus_tag="P5537_14340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004265721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HRV79265.1"
                     /translation="MRTNTLIATLALGAGLLGGGALLVPAFALDKSPAATQTTAPAEA
                     GTLSLQQVQARLEADGYRDFEKIERERNKYEATAIDPQGRRVEVKVDARSGEILEVEV
                     KRDKK"
     gene            complement(2126..2581)
                     /locus_tag="P5537_14345"
     CDS             complement(2126..2581)
                     /locus_tag="P5537_14345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79266.1"
                     /translation="MKNRILIASTLALLISGAVQAQTAAAPDDTPVFGAQIMTEQERV
                     EHRERMRAAGTPEEREQVRLEHHKQMVERARERGVTLPEEPPMRGGMGPGAGKGLGAS
                     MGPGAGRGPGAGMGSGAGMGPGSGMGPGGGPGPQTGEGPRGGAGPGGTR"
     gene            complement(2667..4193)
                     /locus_tag="P5537_14350"
     CDS             complement(2667..4193)
                     /locus_tag="P5537_14350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004378287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HRV79267.1"
                     /translation="MGSIRRRTLLLVLGLLGIALGGISFLGYRDARHEIQELFDARLA
                     QQARLLAGMIPGGMAPDARNALQEALDAGGLGVAAGKETGAEREDGDEALALGHEYEG
                     KLGFVVVDEQGRVLLQSAAAPLGALDMLLAARSGGAAPRRLAEAGEALAGYHTVSLHD
                     GAWRLFLLRDARDRQWILVGEREDVRGELVGKVTLRSLLPDLVGLPLVALLVWLAIGW
                     GLRPLARIAESLQARGPDDLSALALQDVPQELDPVVASLDRLLQQVNALLERERRFLA
                     YAAHELRTPLAVLRIHAQNALQAPDPADRDEALRLMGTGIERATRVVAQLLTLARLEP
                     DASRLKRLVIDLLALVREQLAELTPLADEHGQDLALEADEGADFHLEGDAGSLGILMQ
                     NLVGNAVQHTPPDGCIRVLLEASLAAIVLRVQDSGHGVPPALREKVFERFFRAGGGEG
                     AGLGLAIVARIVELHGGTIALDDCPLGGLEVRVVLPRSPAVRAAAGLHADTENRAVGG
                     "
     gene            complement(4193..4852)
                     /locus_tag="P5537_14355"
     CDS             complement(4193..4852)
                     /locus_tag="P5537_14355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004378285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV79268.1"
                     /translation="MRILLVEDDAALGEGIRVALKPEAYTVDWVQDGAGALHALTHED
                     FALAVLDLGLPRMDGLEVLQRLRAAANAVPVLVLTARDATSDRIAGLDAGADDYLVKP
                     FDVDELKARIRALLRRSANRAQPVLHHREVLLDPVNQQVSYRGQPVALQRKEFLLLHE
                     LLAQPGRVLTRDRLQQALYGWGEEAESNTLEVHIHHLRRKLFPELIRTVRGVGYLVDK
                     V"
     gene            complement(4914..>5420)
                     /locus_tag="P5537_14360"
     CDS             complement(4914..>5420)
                     /locus_tag="P5537_14360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HRV79269.1"
                     /translation="FAELAERAARAVAVEPEAAELRIWHAIVLSTWAGAKGGLGALGL
                     VKEAKAELETALRLDPRALDGSAYTSLGSLYYQVPGWPVGFGDDAQAEKLLKQALAIN
                     PGGIDPNYFYGDFLSRQKRYAEARTALEKALAASDRPGRESADAGRRAEARRLLEQVV
                     AKLAQGAQ"
     assembly_gap    5421..5520
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<5521..6251)
                     /locus_tag="P5537_14365"
     CDS             complement(<5521..6251)
                     /locus_tag="P5537_14365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HRV79270.1"
                     /translation="MELNGSRVLVTGASGGIGEALVEQLCKAGAQVLAVGRDADKLAA
                     AQGRFPHALRALVADLATPAGVDAVAAAARDFGGVDCVVQAAGLNRFGLVEQQDDEAI
                     AAQVALNLVAPMLLSRRLLPLLRERPRAVLLFVGSTFGAIGYPGFAPYSASKFGLRGF
                     AEALRRELADGPVRVLYLAPRATRTAMNASAVVEMNRALGVAMDPPAQVAAAIVQALR
                     DESPERHLGWPERFFARLNRLLPRVV"
     gene            complement(6263..6916)
                     /locus_tag="P5537_14370"
     CDS             complement(6263..6916)
                     /locus_tag="P5537_14370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing redox enzyme family protein"
                     /protein_id="HRV79271.1"
                     /translation="MSFFQQLQDQTVAERDMLFAAPIIQQALAGKVALPSYIAFLTEA
                     YHHVSHTVPLLMACGARLPARLEWLRGAIAEYIDEEYGHQEWILNDLAACGADPEAVR
                     RSQPALPTELMVAYVYDRIARHNPVSFFGMVNVLEGTSIALATRAAGSIRSGLGLPPE
                     AFSYLNSHGSLDLEHMDFFATLMNRLDEDDDRAAVVHTARVVYRLYGDIFRGLPLAA"
     gene            complement(6913..8427)
                     /locus_tag="P5537_14375"
     CDS             complement(6913..8427)
                     /locus_tag="P5537_14375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HRV79272.1"
                     /translation="MSDAFDALRSTLVRHGARPALRGEGEEISYARLLEAIAERRGVL
                     EAVGARRVALALDNGPQWALWDLALLAGGQVCVPLPGFFSPTQQMHVLDSAGIDTLIV
                     DPAAASATLFAGFVPVAPGILQRTPPQLPALPAGTAKITYTSGSTGQPKGVCLSAAAQ
                     LAVAHSVAQIGEGGAVERHLGVLPLATLLENIAGLYAGLLAGARVELLPMRTIGFSGG
                     GGFDPARFLQTLHAHRPHSLILLPQMLLALVGAAEQGHALPAGLRFVAVGGGQVSPRL
                     LQRAEALGLPVYEGYGLSECASVVCLNTPSARRIGTVGRPLPHAGVRIGDDGEVQVRG
                     ARMLGYLGEAPPADALAADAWLGTGDLGHFDDGFLVLHGRKKHQFITAYGRNVNPEWV
                     EAELVQQGAIAQAWVHGEARPENLAVLVPRRADCSDVELEAAVAAANAGLPDYACAHR
                     WLRAEAPFTLANGLLTANGRLRRAALAAHYLPRSGADGGAPGVHFTSFSDETET"
     gene            complement(8411..>8920)
                     /locus_tag="P5537_14380"
     CDS             complement(8411..>8920)
                     /locus_tag="P5537_14380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004372765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermostable hemolysin"
                     /protein_id="HRV79273.1"
                     /translation="HFMPRLFALEAADGSLHGAVGCRGAAEQGLFLERYLDEPVESVI
                     ARRTGERVEREGIVEVGNLAAHGAGTARLLIIALTRILAAEGLRWVCFTGTPALINSF
                     RRLGLDPLTLGPADPRRMGAELPEWGSYYEAGPLVMAGEIPGGDRALAGAGRYFQPER
                     EEPARVRCL"
BASE COUNT         1338 a         3233 c         3100 g         1149 t
ORIGIN      
        1 gaagttcagc gccacgcccg cgcccatgac ctgcagcacg ccgaagcgct tgatcaggtg
       61 gccggtgaag aagcccggcg cgaacatgcc gatcacgtgc cactccagca ccagcgccgc
      121 gtccgagaag ggcatgccgc acacgtccat cgccagcggg gtggccgcca tcagcaggtt
      181 catcacgccg tagctcatcg ccgcggccag cgcggacacg atgaacaccg gctggcgcac
      241 gatctcgccc agcgcccgcc cgccgtcggc gcccggcttc ttagccggct cggacggaaa
      301 gcggatgccc gccatcaccg ccatcgacac cagcgccacc accgcgagcg cgagatagga
      361 gccgaggaag ggcgcgccga gcgcctcgcg cgtgtggttg gccaggttgg gcccgatcac
      421 cgcaccgatg agcccgcccg ccagcaccag cgacaccgcc ttctcgcgga aggacggcgg
      481 cgccagctcg ccggccgcga agcggtagag ctggccgttg gcgctgtagt agccggcgat
      541 cacagtgccc gccacgagca gccagaagct gccgatcgac agcgcgaagg cgcacagcag
      601 cgcggtgagg aaggccacca gcaggccgag ctggaaggac acctgccgcc cccagcggcg
      661 ctggctgcgc gccaccagcc cggtcgacag cgccccaccc accacatagc ccatcaccgg
      721 cagcgtcgcc atccagccca ccggcgccag actgaagccc accagtccgt tgatggcgat
      781 gaacaccacg ttgttggtca ggaacaggcc ctgcgcgatc gccagcagcc agaggttctt
      841 cttcatcggt aaatgctgat ttgtcgggga ggctgaactc tacccgttct gatcgagcag
      901 cgccccattc gcggccccca ttcgcggccc cccattcgcg gcccccattc gcggctgccg
      961 ccgctcctac agggggtagc ggttcgtgta ggacgtcgag atgcggcaac gccagaagca
     1021 tgtcggttcg tgcagggctt agagatgcgg caacgccaaa agcaagtcgg ctcgcgcagg
     1081 gcgtcgaggg gtggaaacgc ttcgggtacg cgccggttca tgtaggagcg ccggcaggcg
     1141 cgaatgcggc gcgcgatatc acgacgcggg tcggtcgtgg gatcgccgaa ttcgcggctg
     1201 ccgccgctcc tacagggggc agcggttcgt gtagggcgtc gacatgcggc aacgccagaa
     1261 gcatgtcggt tcgtgcaggg cgtcgagaga tggaaacgct tcgggtacgc gtcggtttat
     1321 gtaggagcgc cggcaggcgc gaatgcggcg cgcgggatta cgatgcgcgt cggtcgccgg
     1381 atcgccgaat tcgcggctgc cgccgctcct acaggggacg gcggttcgtg tagggcgtcg
     1441 agatgcggga acgccagggg cgtaccggtt cgtgtgcggc gtcgaagtgc gggaacgcca
     1501 cgggcatgtc ggctcgcgca gggcgtcgag ggtggaaacg cttcgggtgc gcaccggttc
     1561 atgtaggagc gccggcaggc gcgaatgcgg cgatcgagcc gcgtcaccca cccggcgcag
     1621 ctgagaaatc cctgaaaacc tccttcagca aggcttcatg cacccgggcg caggatgcac
     1681 ccacggtcga agcgcgaccg cacaagcccc caaggagaaa gatcatgcgc acgaacaccc
     1741 tcatcgccac cctcgccctc ggcgccggcc tgctcggcgg cggtgcactg ctcgtccccg
     1801 ccttcgcgct ggacaagtcc cccgcggcaa cgcaaaccac ggctccggcc gaagccggaa
     1861 ccctgagcct acagcaggtc caggcccggc tggaagccga cggctatcgc gacttcgaga
     1921 agatcgagcg cgagcgcaac aagtacgagg cgacggccat cgacccgcag ggccgccgcg
     1981 tcgaggtcaa ggtcgacgcc cgcagcggcg agatcctgga ggtcgaagtc aaacgcgaca
     2041 agaagtgatc agacgagcgc gggaggcgcc gcggcgcccc ccgggagctt tcggcaaccg
     2101 ttgctacacg ggtccgcagc gcgactcaac gcgttccgcc aggaccggca ccgccacgcg
     2161 gcccttcacc ggtctgcgga cccggcccgc cccccggccc catgcccgag cccggaccca
     2221 tgcccgcgcc gctccccatt ccggctcccg gtccgcggcc tgcgcccggc cccatgctgg
     2281 cgccgagacc ttttcctgcc cccggcccca tgccgccgcg catcggcggc tcctcgggca
     2341 gggtcacgcc gcgctcgcgg gcgcgctcga ccatctgctt gtgatgctcc aggcggacct
     2401 gctcgcgctc ctcgggcgtg cccgccgcac gcatgcgctc gcggtgctcc acgcgctcct
     2461 gctcggtcat gatctgggcg ccgaagacgg gcgtgtcgtc gggcgcggca gcggtctgcg
     2521 cctgcactgc accggaaatc aacaacgcga gcgtgctggc gatcaagatg cgattcttca
     2581 tggcgacctc cttgacgatg gtgaagcgat cccgtcgtgc cccccgcgcc accagcctcg
     2641 acggggcacc acggcctgat tccaatctag ccccccactg cgcggttttc agtatcggcg
     2701 tgtagccccg cagcagcgcg cacggcaggc gagcgcggca gcacgacgcg gacctccagg
     2761 ccgccgaggg gacaatcgtc gagcgcgatc gtcccgccat ggagttcgac gatgcgcgcg
     2821 acgatcgcca ggccgaggcc cgcgccttcc ccgccaccgg cgcggaagaa gcgctcgaac
     2881 accttctcgc gcagcgccgg cggcacgccg tggccgctgt cctgcacgcg cagcacgatg
     2941 gccgcaagcg aggcctccag cagcacgcgg atgcagccgt cgggcggcgt gtgctgcacc
     3001 gcgttgccca ccaggttctg catcaggatg cccaggctgc cggcgtcgcc ctcgaggtgg
     3061 aagtcggccc cctcgtccgc ctcgagggcg aggtcctgac catgttcgtc ggcgagcggg
     3121 gtgagctcgg cgagttgctc gcggacaagc gcgagcaggt cgatcaccag cctcttcagc
     3181 cggctcgcgt cgggttcgag gcgggccagt gtcagcaact gcgccaccac ccgggtggcc
     3241 cgctcgatgc ccgtgcccat cagtcgaagc gcctcgtcgc gatccgccgg atcgggcgcc
     3301 tgcagcgcgt tctgcgcatg aatgcgcagc accgccagcg gggtgcgcag ctcgtgcgcg
     3361 gcgtaggcga ggaagcggcg ctcgcgttcg agcagcgcgt tgacctgctg cagcaggcgg
     3421 tcgagcgagg ccaccaccgg atcgagctcc tgtggcacat cctgcagcgc gagcgccgag
     3481 aggtcgtccg ggccgcgcgc ctgcagcgac tcggcgatgc gcgcgagcgg gcgcagcccc
     3541 cagccgatcg ccagccacac cagcagggcg accagcggca gccccacgag atcgggcagc
     3601 aggctgcgca aggtgacctt gccgacgagc tcgccacgca cgtcctcgcg ctcgccgacc
     3661 aggatccact ggcgatcgcg cgcatcccgc agcaggaaca gccgccaggc gccatcgtgc
     3721 aggctcaccg tgtgatagcc cgcaagcgcc tcccccgcct cggcgagccg ccgcggcgca
     3781 gcgcccccgg agcgtgcggc gagcagcatg tcgagcgccc cgagcggcgc cgccgcggac
     3841 tgcagcagga cccgcccctg ctcgtccacc accacgaagc cgagcttgcc ctcgtactcg
     3901 tggcccagcg ccagcgcctc gtcgccgtcc tcccgctcgg cgcccgtctc cttccccgcc
     3961 gcaacaccga ggccccctgc atcgagcgct tcctgcagcg cgttgcgcgc gtccggcgcc
     4021 atgccgcccg ggatcattcc ggccagcagg cgcgcctgct gggcgagacg ggcatcgaag
     4081 agctcctgga tctcgtggcg ggcgtcgcga tagccgagga aggagattcc gccgagcgcg
     4141 atgccgagca ggccgagcac gagcagcaag gtgcggcgac ggatcgagcc catcagacct
     4201 tgtccaccag atagcccacc ccgcgcacgg tgcggatcag ctcggggaag agcttgcgcc
     4261 gcaggtggtg gatgtgcacc tcgagcgtat tgctctcggc ctcctcgccc cagccgtaca
     4321 aggcctgctg caggcggtcg cgggtcagca cgcggccggg ctgggcgagc agctcgtgca
     4381 gcagcaggaa ctccttgcgc tgcagggcca caggctggcc acggtagctc acctgctggt
     4441 tcaccgggtc gaggagcacc tcgcggtggt gcagcaccgg ctgcgcgcga ttggcgctgc
     4501 ggcgcagcag cgcgcggatg cgggccttga gctcgtcgac gtcgaagggc ttgaccagat
     4561 agtcgtccgc gcccgcatcc agccccgcga tgcggtcgct ggtggcgtcg cgcgcggtga
     4621 ggaccagcac cggcaccgcg ttggcggcgg cgcgcaggcg ctgcagcacc tcgagcccgt
     4681 ccatgcgcgg caggccgagg tcgagcacgg cgagcgcgaa gtcctcgtgg gtgagcgcgt
     4741 gcagcgcgcc cgcgccgtcc tgcacccagt cgaccgtgta cgcctccggc ttgagcgcga
     4801 cgcggatccc ctcgccgagc gcggcatcat cctcgacgag caggatgcgc atcccttccc
     4861 tccctcgtgt tccctgcatt catgggcgct gcgttgatcc gcatattgga cccttactgc
     4921 gcgccttgcg ccagcttcgc gaccacctgc tcgagcaggc gccgcgcctc cgcgcgccgg
     4981 ccggcgtcgg cgctctcacg cccggggcgg tcggaggcgg cgagcgcctt ctctagcgcc
     5041 gtgcgcgctt cggcgtagcg cttctgccgc gacaggaagt cgccgtagaa gtaattggga
     5101 tcgatgccgc cggggttgat cgccaaggcc tgcttcagca gcttttcggc ctgcgcgtcg
     5161 tcgccgaagc ccaccggcca tccgggcacc tgatagtaga ggctgccgag gctggtgtag
     5221 gccgagccgt cgagcgcgcg cgggtcgagc cgcagggcgg tctcgagctc ggccttggcc
     5281 tccttgacga ggccgagcgc gccgagcccg cccttcgccc ctgcccaggt gctcaggacg
     5341 atggcgtgcc agatgcgcag ctcggccgcc tcgggctcga cggcgaccgc cctcgcggcg
     5401 cgctcggcga gctcggcgaa nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5521 accacgcgcg gcagcagccg gttgaggcgg gcgaagaagc gctccggcca gccgaggtgg
     5581 cgctcgggcg actcgtcgcg cagcgcctgc acgatcgcgg cggcgacctg cgccggcggg
     5641 tccatcgcca cgccaagcgc gcggttcatc tcgaccaccg cgctggcgtt catcgcggtg
     5701 cgcgtcgcgc gtggcgccag gtagagcacg cgcaccgggc cgtcggcgag ctcgcggcgc
     5761 aaggcctcgg cgaagccgcg cagaccgaac ttgctcgcgc tgtagggcgc gaagccggga
     5821 tagccgatcg cgccgaaggt cgagccgacg aacagcagca ccgcgcgcgg gcgctcgcgc
     5881 agcaagggca gcaggcgccg ggagagcagc atcggcgcca ccaggttgag cgcaacctgg
     5941 gccgcgatgg cctcgtcgtc ctgctgctcg acgaggccga agcggttgag gccggcggcc
     6001 tggaccacgc agtcgacgcc gccaaaatcc cgcgccgcgg cagccaccgc atcgacgccg
     6061 gcgggggtgg cgagatcggc gacgagcgcg cgcagcgcgt gcggaaagcg cccctgcgcg
     6121 gccgcgagct tgtccgcgtc gcgaccgacc gccagcacct gcgcgcccgc cttgcaaagc
     6181 tgctcgacca gcgcctcgcc gatgcccccg ctcgcgccgg tgaccagcac gcggcttccg
     6241 ttcagttcca tcgcggcgct cctcaggccg ccagcggcag gccgcggaaa atgtcgccgt
     6301 acaggcgata cacgacgcgc gcggtgtgca ccaccgcggc acggtcgtcg tcctcgtcga
     6361 gccggttcat cagcgtcgcg aagaagtcca tgtgctcgag gtcgaggctg ccgtgcgagt
     6421 tcaggtagct gaaggcctcg ggcggcagcc ccaggccgct gcggatcgac cccgccgcgc
     6481 gggtggcgag ggcgatgctc gtgccctcga gcacgttgac catgccgaag aagctcaccg
     6541 ggttgtggcg cgcgatgcgg tcgtagacat aggccaccat cagctcggtg gggagcgccg
     6601 gctggctgcg gcgcaccgcc tcggggtcgg cgccgcaggc ggcgaggtcg ttcaggatcc
     6661 actcctggtg gccgtactcc tcgtcgatgt attcggcgat cgcgccgcgc agccattcga
     6721 gccgtgcggg caggcgcgcg ccgcaggcca tcagcagcgg cacggtgtgg ctgacgtggt
     6781 gatacgcctc ggtgaggaag gcgatgtagc tcggcagcgc gaccttgccg gcgagcgcct
     6841 gctggatgat cggcgcggcg aacagcatgt cgcgctcggc cacggtctgg tcctggagtt
     6901 gctggaagaa gctcatgttt cggtctcgtc gctgaaggag gtgaagtgga cgcccggggc
     6961 gccgccatcg gcgccgctgc gcggcaggta gtgcgccgcg agcgcagcgc ggcgcaggcg
     7021 gccgttggcg gtgaggaggc cgtttgccag ggtgaagggc gcctcggcac gcagccagcg
     7081 gtgcgcgcac gcgtagtcgg gcaggcccgc gttggcggcg gccaccgccg cctcgagctc
     7141 gacgtcgctg cagtcggcgc ggcgcggcac gagcacggcg aggttctcgg ggcgggcctc
     7201 accgtgcacc caggcctgcg cgatcgctcc ctgctggacc agctccgcct cgacccactc
     7261 ggggttcacg ttgcgcccgt aggcggtgat gaactggtgc ttcttgcgcc cgtgcaggac
     7321 caggaagccg tcgtcgaaat ggccgaggtc gccggtgccc agccacgcgt cggccgccaa
     7381 cgcgtccgcc ggcggcgcct cgccgaggta gccgagcatg cgcgcgccgc gcacctgcac
     7441 ctcgccgtcg tcgccgatgc gcacccctgc gtgcggcaag ggccgcccca ccgtgccgat
     7501 acggcgcgcc gacggggtgt tgagacacac caccgaggcg cactcggaca ggccgtagcc
     7561 ctcgtacacc ggcagcccga gcgcttcggc acgctgcagc agccgcggcg acacctgccc
     7621 gccgcccacc gcgacgaaac gcaggccggc gggcagcgca tggccttgct cggcggctcc
     7681 gaccagggcg agcagcatct gcggcaacag gatcaggcta tgcggtcgat gcgcatgcag
     7741 ggtctgcagg aagcgcgccg gatcgaaccc cccgccgccg ctgaagccga tcgtgcgcat
     7801 cggcagcagc tccacacgcg caccggccag caggccggcg tacagcccgg cgatgttctc
     7861 cagcagcgtc gccagcggca gcacgcccag atggcgctcg accgcgccgc cctcgccgat
     7921 ctgcgcgacg ctgtgcgcca cggcgagctg cgcagccgcg ctcaggcaca cccccttggg
     7981 ctggccggtg ctgccggaag tgtaggtgat cttcgccgtg cccgcgggca gcgccggcag
     8041 ctgcggcggc gtgcgctgca ggatcccggg cgccaccggc acgaagcccg caaaaagcgt
     8101 cgcacttgcg gccgccggat cgacgatcag cgtgtcgatg ccggcgctgt cgagcacgtg
     8161 catctgctga gtcggcgaga agaagccggg caagggcaca cagacctgcc cgccggcaag
     8221 cagcgcgaga tcccagagcg cccactgcgg gccgttgtcg agcgcgagcg ccacgcgccg
     8281 cgcacccacc gcttcgagca cgccccgacg ctcggcgatc gcctcgagca gtcgagcgta
     8341 cgaaatctcc tcgccctcgc cacgaagcgc ggggcgcgcc ccgtggcgca caagcgtgct
     8401 ccgcagggcg tcaaaggcat cggacacggg ccggctcctc gcgctcgggc tgaaaatagc
     8461 gccccgcgcc cgcgagggcg cggtccccac ccgggatctc ccccgccatc accagcgggc
     8521 cggcctcgta gtagcttccc cactccggca gttccgctcc catgcggcgc ggatccgctg
     8581 gaccgagcgt gagcgggtcg agaccgaggc ggcgaaagct gttgatcagc gctggcgtgc
     8641 cggtgaagca cacccagcgc aggccctcgg cagcgaggat gcgggtgagc gcgatgatca
     8701 gcaggcgcgc ggtgccggcc ccgtgggcgg cgaggttgcc gacctcgacg atcccctcgc
     8761 gctccacccg ctcgcccgtt cgccgcgcga tgacgctctc gacgggctcg tcgaggtagc
     8821 gttcgaggaa gagcccctgc tccgccgcgc cgcggcagcc gaccgcgccg tgcaggctgc
     8881 catcggcggc ttcgagcgca aacagccggg gcatgaagtg
//
LOCUS       DAOTIN010000129         8746 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_9625_length_8746_cov_9.352779, whole genome shotgun sequence.
ACCESSION   DAOTIN010000129 DAOTIN010000000
VERSION     DAOTIN010000129.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 8746)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 8746)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8746
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_9625_length_8746_cov_9.352779"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(155..1483)
                     /locus_tag="P5537_14385"
     CDS             complement(155..1483)
                     /locus_tag="P5537_14385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004365066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiH family protein"
                     /protein_id="HRV79274.1"
                     /translation="MNEPSSAAVPASARGVALARLLVYSLIGLVIFFVPFEIGGKSTI
                     VLDHAASYLVKDARTLVVVIAMLLMAYGALEPWMSGSWRENAVAVAFSVLKVLGLAIG
                     VAFLFKLGPEVVYAPGMLPFLFEKLVLSLALIVPLGSLALVFLIGFGLLELIGVLMQP
                     VMRPIWRTPGKSAIDAVASFVGSYSVGLLITARMYAQRHYTLREAAIIATGFSTVSAP
                     FMVIVAKTLNLMPAWNLYFWGCMAITFAVTAVSARIYPISRLPSEGSADPVLPEGRSR
                     VQAAWDAGLEHAHIAPPLWVSLRETFADGLRMTAAILPSILAVGLLGLLAAKYTPVFD
                     ILGVLLYPVTWAFGLDEPMTVARAVASGLAEMFLPAMLMKEADVVVRFTVAVVSVSSV
                     LFLSASIPCVIATRIPLRMRDLLLVWLQRTFLSLVLTIPFAQFAHKLGWL"
     gene            complement(1540..2496)
                     /gene="hutG"
                     /locus_tag="P5537_14390"
     CDS             complement(1540..2496)
                     /gene="hutG"
                     /locus_tag="P5537_14390"
                     /EC_number="3.5.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015436887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050415 - formimidoylglutamase activity
                     [Evidence IEA];
                     GO_process: GO:0019556 - histidine catabolic process to
                     glutamate and formamide [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formimidoylglutamase"
                     /protein_id="HRV79275.1"
                     /translation="MSTDRNTMDAWSGRVDPEPDSPRWHQVIGAFADTTATTAPGAVL
                     LGFACDEGVRRNKGRTGAAAAPAAIRKALAGLAWHRSAPAYDAGDVVCADGELEAAQA
                     RLAHALAEVLAGGHFPLVLGGGHEVAFGTWQGLAAHLERSGERAPRIGIINLDAHFDL
                     RDPAHAHSSGTPFAQIAQAAAARGWPFRYACLGVSRASNTRALFRRAAELDVLVREDR
                     EITPANLAEVQAALDVFIADCEHLYLTIDIDVLPACEAPGVSAPAARGVPLALLEELA
                     EQVRDSGKLRVADLAELNPEHDIDQRTARVAARLIHLLTLNG"
     gene            complement(2493..3737)
                     /gene="hutI"
                     /locus_tag="P5537_14395"
     CDS             complement(2493..3737)
                     /gene="hutI"
                     /locus_tag="P5537_14395"
                     /EC_number="3.5.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015436886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050480 - imidazolonepropionase activity
                     [Evidence IEA];
                     GO_process: GO:0006548 - histidine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazolonepropionase"
                     /protein_id="HRV79276.1"
                     /translation="MNIQAGQSMLWREATVFDGLHTLPGPMAVRVDCDRITGVWPEAE
                     FDPARAEGCIEAGRGGLMTPGLVDCHTHLVFGGSRADEFEQRLEGVSYAEIARAGGGI
                     LSTVRATRAASPDQLFDAALPRLQALVDDGATTVEIKSGYGLAMADELKMLRVARRLG
                     RAQEGGLPVRIVTTLLGAHALPPEFAGDADGYIDEVCARMIPAAAAEGLADAVDVFCE
                     GIAFSPAQCERVFEAAQRHGLAIKAHAEQLSNLGGAALAARHGALSADHIEYLDEAGV
                     QAMAAAGTVGVLLPGAFLTLRETQLPPVELLRRHGVPMALATDANPGSSPMFMPTLML
                     NLGCTLFRLTPREALAGMTAHGARALGLADSGRIAAGQRADLCVWQAGHSAELAYAVQ
                     PGRLRQRVFGGRITHDRFPEAR"
     gene            4033..4965
                     /locus_tag="P5537_14400"
     CDS             4033..4965
                     /locus_tag="P5537_14400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004375865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HRV79277.1"
                     /translation="MELKWLEDFLSLADSGSFSRSAEQRHVSQPAFSRRIRALEAWLG
                     VALVDRSTFPTRLTEAGEAFKGPAADLIHRLHAARALVRGHQKTAGDALVFAVPHTLA
                     FAFFPAWLGRLKAEFGEVPTRLIAGNVHDVVTMLVEGGCDLLLCYHHPTHPVWLDPAR
                     FEGIQLAVERVRPYLPRRLAGTSGWQLPGAAESPIPFLRYGPNTYLRRMVDTILDRAA
                     RPAHLALQYESDMAESLKAMLLAGHGLAFLPASAVAREVDRGEVVVAGGPEWSLEMEV
                     RLYRDRANTRPELLRLWQHLASPTPDAPRPTPHS"
     gene            5081..6391
                     /locus_tag="P5537_14405"
     CDS             5081..6391
                     /locus_tag="P5537_14405"
                     /EC_number="1.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004375867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Glu/Leu/Phe/Val dehydrogenase"
                     /protein_id="HRV79278.1"
                     /translation="MSATQQDPTSLDRVGGLSYLNPAAPEPWASFVEQIERVRPHLGA
                     LERWIETLKHPKRALIVDVPIERDDGTVAHYEGYRVQHNLSRGPGKGGVRFHPDVTLN
                     EVMALAGWMTIKNAAVGLPFGGAKGGIRVDPTSVSKGELQRITRRYTSEIGIIIGPDK
                     DIPAPDVGTNAMTMAIMMDTFSMNRGGTATGVVTGKPIALGGSLGRQEATGRGVFIAA
                     REAARHLRLPIEGARVVVQGFGNVGGIGARMFHDAGARVIAIADHTAILVNEAGIDIP
                     AALAHTAANGGLKGFGGAAPIDPEEFWRLECEFLVPAALEGQLTVERASHARARIVVE
                     GANGPTTPAADDILHERGILVVPDVLANAGGVTVSYFEWVQDFSSFFWTEDEINERLE
                     RIMVAAFTAIWKVAQEKQVSLRTAAFIIACARVLEARAERGLYP"
     gene            complement(6790..7551)
                     /locus_tag="P5537_14410"
     CDS             complement(6790..7551)
                     /locus_tag="P5537_14410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV79279.1"
                     /translation="MNWHAVRAIYLFEMARTKRTLLQSVLAPVITTSLYFVVFGAAIG
                     ARIPEVEGVSYGAFIVPGLIMLNLLTQSVSNASFGIFFPKFSRTIYEILSAPVSHFEI
                     VLSYVGAAATKAVILSLIILATATFFVPLRIEHPLWMVGFLLLTAVSFSLLGFILGIW
                     ADNFEKLQLVPLLIITPLTFLGGSFYSIDMLPAAWRTLSLFNPVVYLVSGFRWSFYGT
                     ADVAVGVSLAMTLLFLAVFVGVATWMLRTGYRLKP"
     gene            complement(7548..8495)
                     /locus_tag="P5537_14415"
     CDS             complement(7548..8495)
                     /locus_tag="P5537_14415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004375874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV79280.1"
                     /translation="MDSIISISGLSKTYASGFAALKGVDLDIRRGEIFALLGPNGAGK
                     TTLISVVCGLVNASAGTVRVDGHDIVRDYRAARALIGLVPQELTTDAFETVWNTVSFS
                     RGLFGKPPDPAYLEQLLKDLSLWAKKDAKLMMLSGGMKRRVLIAKALSHEPRILFLDE
                     PTAGVDVELRRDMWQLVRRLRDSGVTVILTTHYIEEAEEMADRIGVIAKGALILVEDK
                     AALMKKLGGKQLTLQLAAPLAQIPPALARYGLALGKGGGTLVYRYEAETEDNAIADLL
                     QDLAAAGIAFADLHTTQRSLEEIFVSLVSEREPAGEGAR"
BASE COUNT         1345 a         3062 c         3145 g         1194 t
ORIGIN      
        1 gcggcttcgg tgagccagct cttggcggtg cgttcggtgc cgcgcggggc gcggatctcg
       61 atgtcgcgga acttggtcat gggggtctcc gggggtgggg tggggggttg gaaggcgggg
      121 ttggggtcgt tggggtcggg ggtttgcgcg gcggtcatag ccagccgagc ttgtgggcga
      181 actgcgcgaa ggggatggtg agcaccaggc tcaggaaggt gcgctgcagc cagaccagca
      241 gcaggtcgcg catgcgcagc gggatgcgcg tggcgatcac gcaggggatc gaggcggaca
      301 ggaagagcac gctgctgacc gagaccacgg cgacggtgaa gcgcacgacg acgtcggcct
      361 ccttcatcag catcgcgggc aggaacatct cggccaggcc cgaggccacc gcgcgcgcca
      421 ccgtcatcgg ctcgtcgagg ccgaaggccc aggtcaccgg gtagagcagc acgccgagga
      481 tgtcgaacac cggggtgtat ttggcggcga gcaggccgag caggcccacg gcgaggatgc
      541 tgggcaggat cgcggcggtc atgcgcaggc cgtcggcgaa ggtctcgcgc agcgacaccc
      601 acagcggcgg cgcgatgtgc gcatgctcca ggccggcgtc ccaggccgcc tgcacgcggc
      661 tgcgaccctc gggcaggacc gggtcggcgc tgccctcgct gggcaggcgc gagatcgggt
      721 agatgcgcgc gctcaccgcg gtgaccgcga aggtgatcgc catgcagccc cagaagtaca
      781 ggttccatgc cggcatcagg ttcagggtct tggcgacgat gaccatgaag ggcgccgaca
      841 cggtggagaa gccggtggcg atgatcgccg cctcgcgcag ggtgtagtgg cgctgggcgt
      901 acatgcgcgc ggtgatcagc aggccgaccg agtagctgcc gacgaaggag gccaccgcgt
      961 cgatcgccga cttgcccggc gtgcgccaga tcggccgcat caccggctgc atcagcacgc
     1021 cgatcagctc gagcagcccg aagccgatca ggaagacgag cgcgagcgag ccgagcggca
     1081 cgatgagcgc cagggacagc accagcttct cgaacaggaa gggcagcatg ccgggggcgt
     1141 acaccacctc cggcccgagc ttgaacagga aggcgacgcc gatcgccagg ccgagcacct
     1201 tgagcaccga gaaggcgacg gcgaccgcgt tctcgcgcca gctgcccgac atccagggct
     1261 cgagcgcgcc ataggccatc agcagcatcg cgatgacgac gaccagcgtg cgcgcgtcct
     1321 tgaccagata gctcgccgca tggtcgagca cgatggtcga cttgccgccg atctcgaagg
     1381 gcacgaagaa gatcaccagc ccgatcaggc tgtatacgag caggcgcgcg agcgcgacgc
     1441 cgcgggcgga cgcgggcacg gccgcgctgg atggttcgtt catcggggtc tcctccggca
     1501 gatgcttttt gtaatggctt gcggctgtgc cgcgcgggtt cagccgttca aggtgagcag
     1561 gtggatcagg cgcgcggcga cgcgggcggt gcgctggtcg atgtcgtgct cggggttgag
     1621 ctcggcgagg tcggcgacac gcagcttgcc gctgtcgcgc acctgctcgg cgagctcctc
     1681 caggagggcg agcgggacgc cgcgcgcggc cggcgcgctg acgccgggcg cctcgcaggc
     1741 gggcagcaca tcgatatcga tggtcaggta gaggtgctcg cagtcggcga tgaagacgtc
     1801 gagcgcggcc tgcacctcgg ccaggttcgc cggggtgatc tcgcggtcct cgcgcaccag
     1861 cacgtcgagc tcggcggcgc ggcggaacag cgcgcgcgtg ttcgaggccc ggctcacgcc
     1921 caggcaggcg tagcggaagg gccagccgcg cgccgcggcg gcctgggcga tctgcgcgaa
     1981 gggggtgccg gacgaatgcg cgtgggcggg gtcgcgcagg tcgaagtggg cgtcgaggtt
     2041 gatgatgccg atgcgcgggg cgcgctcgcc gctgcgctcg agatgcgcgg ccagcccctg
     2101 ccaggtgccg aaggcgacct cgtggccgcc accgagcacg agcgggaaat ggccgccggc
     2161 gaggacctcc gcgagcgcgt gcgccaggcg cgcctgcgcc gcctcgagct cgccgtcggc
     2221 gcacaccacg tcgccggcgt cgtaggccgg cgcgctgcgg tgccaggcca ggccggcgag
     2281 cgccttgcgg atcgccgccg gcgccgcagc ggcgcccgtg cgccccttgt tgcggcgcac
     2341 gccctcgtcg caggcgaagc cgagcaggac cgcgcccggg gcggtcgtgg cggtggtgtc
     2401 ggcgaaggcg ccgatcacct gatgccagcg cgggctgtcg ggctcggggt cgacgcggcc
     2461 gctccaggcg tccatggtgt tgcgatcggt gctcatcgtg cctccgggaa acggtcgtgg
     2521 gtgatgcggc cgccgaacac gcgctggcgc aggcggccgg gctgcacggc gtaggccagc
     2581 tcggcgctgt ggccggcctg ccacacgcac aggtcggcgc gctggccggc ggcgatgcgg
     2641 ccgctgtcgg cgaggccgag ggcgcgcgcg ccgtgcgcgg tcatgccggc gagcgcctcg
     2701 cgcggggtga ggcggaacag ggtgcagccc aggttcagca tcagcgtggg catgaacatc
     2761 ggcgagctgc cggggttggc gtcggtggcg agcgccatcg gcacgccgtg gcggcgcagc
     2821 agctcgaccg gcggcagctg cgtctcgcga agggtcagaa aggcgccggg cagcagcacg
     2881 cccaccgtgc cggccgcggc catcgcctgc acgccggcct cgtcgaggta ttcgatgtga
     2941 tcggccgaga gcgcgccatg gcgtgcggcg agcgccgcgc cgcccaggtt ggagagctgc
     3001 tcggcgtgag ccttgatcgc caggccgtgg cgctgcgcgg cctcgaaaac gcgctcgcac
     3061 tgcgccgggc tgaaggcgat gccctcgcag aacacatcga cggcgtcggc caggccctcg
     3121 gccgcggccg cggggatcat gcgcgcgcag acctcgtcga tgtagccgtc ggcgtcgccg
     3181 gcgaactcgg gcggcagcgc gtgcgcgccg agcagggtgg tgacgatgcg caccggcagc
     3241 ccgccctcct gcgcccggcc gaggcggcgc gcgacgcgca gcatcttgag ctcgtcggcc
     3301 atggcgaggc cgtagccgga cttgatctcc accgtggtgg cgccgtcgtc gaccagcgcc
     3361 tgcaggcgcg gcagggcggc atcgaagagc tgatcggggc tcgctgcgcg ggtggcgcgc
     3421 acggtgctga ggatgccacc gccggcgcgc gcgatctcgg cgtagctcac gccctccagg
     3481 cgctgctcga actcgtcggc gcggctgccg ccgaacacca ggtgggtgtg gcagtcgacc
     3541 aggccgggcg tcatcagccc gccgcggccg gcctcgatgc agccctcggc gcgcgcggga
     3601 tcgaactcgg cctccggcca cacgccggtg atgcggtcgc aatcgacgcg caccgccatc
     3661 ggccccggca gcgtgtgcag gccgtcgaac acggtcgcct cgcgccacag catggactgg
     3721 cccgcttgta tgttcattta tctactcatt aaaatctatt tgtctataca ttaatgaatg
     3781 aaacgccgcc ggtcaagccc tcgaccgccg gtgctatgct tcccgaggtc ggcacgctgc
     3841 cggggacgcg ccgctcaacc gtgacagacc ggggctgcaa gcttgcccgc cggagcgtgc
     3901 ggtgcgggag ttcatgcgcg ggcgggcccg cgtctgcggc cgcggggctc gcaccggggg
     3961 ccgcgcctca ccgccacact cgccgatatc tgtatataca attcgctcca tcaccccctg
     4021 caggcgccct ccatggaact caaatggctt gaagacttcc tcagcctcgc cgacagcggc
     4081 agcttctcgc gctcggccga gcagcgtcac gtgtcgcagc ccgcgttctc gcgccgcatc
     4141 cgcgcgctcg aggcctggct gggggtggcg ctggtagacc gcagcacctt cccgacccgg
     4201 ctgaccgagg cgggcgaggc cttcaagggg ccggcggcgg acctcatcca ccgcctgcat
     4261 gccgcgcgcg cgctggttcg cggccaccag aaaaccgcgg gcgatgcgct cgtgttcgcc
     4321 gtgccgcaca cgctcgcctt cgccttcttc ccggcctggc tggggcggct caaggccgag
     4381 ttcggcgagg tgcccacccg gctgatcgcc ggcaacgtgc atgacgtggt gaccatgctg
     4441 gtggaaggcg gctgcgatct gctgctgtgc taccaccatc ccacccaccc ggtatggctc
     4501 gatcccgcac gcttcgaagg catccagctc gcggtcgagc gcgtgcgccc ctacctgccg
     4561 cggcggctgg cggggacatc gggctggcag ctgcccggcg cggccgagtc ccccatcccc
     4621 ttcctgcgct acgggcccaa cacctacctg cgccgcatgg tcgacaccat cctcgaccgc
     4681 gccgcgcgcc cggcccacct tgccctgcag tacgaatccg acatggccga gagcctcaag
     4741 gccatgctgc tcgccggcca tggcctcgcc ttcctgcccg cgagcgcggt cgcgcgcgag
     4801 gtggaccgcg gcgaggtggt cgtcgccggc ggcccggaat ggagcctgga aatggaggtc
     4861 cgcctgtacc gcgaccgcgc caacacgcgg ccggagctgc tgcgcctgtg gcagcacctg
     4921 gccagcccga ctcctgacgc cccgcgcccc actcctcact cctgacgcct cacgccccac
     4981 ctatgcacaa gacgcatgac ccgatgtagc aacggcatgc ctcgcgggtg cgcccatccg
     5041 cacaatgcgc tcacttttca caccacacga ggaagacaag atgagtgcga cacaacaaga
     5101 cccgaccagc ctggaccgcg tcggcgggct ttcctacctg aacccggccg ctcccgagcc
     5161 gtgggcgagc ttcgtcgagc agatcgagcg cgtgcgcccc cacctcggcg cgctcgagcg
     5221 ctggatcgag accctcaagc accccaagcg cgcgctgatc gtcgacgttc cgatcgagcg
     5281 tgacgacggc accgtcgccc actacgaggg ctaccgcgtg cagcacaacc tgtcgcgcgg
     5341 cccgggcaag ggcggcgtgc gcttccaccc cgacgtcacc ctcaacgagg tgatggcgct
     5401 ggccggctgg atgacgatca agaacgccgc ggtcggcctg cccttcggcg gcgccaaggg
     5461 cggcatccgc gtcgacccga cgagcgtcag caaaggcgag ctgcagcgca tcacccggcg
     5521 ctacacctcc gagatcggca tcatcatcgg cccggacaaa gacatccccg cccccgacgt
     5581 cggcaccaac gcgatgacga tggcgatcat gatggacacc ttctcgatga accgcggcgg
     5641 caccgccacc ggcgtcgtca ccggcaagcc gatcgcgctc ggcggcagcc tgggccgcca
     5701 ggaagccacc ggccgcggcg tgttcatcgc cgcgcgcgag gccgcccgcc acctgcgcct
     5761 gccgatcgag ggcgcgcgcg tggtcgtgca gggcttcggc aacgtcggcg gcatcggcgc
     5821 gcgcatgttc cacgacgccg gcgcgcgcgt gatcgcgatc gccgaccaca ccgccatcct
     5881 ggtgaacgag gccggcatcg acatccccgc cgcgctcgcg cacaccgccg cgaacggcgg
     5941 cctgaagggc ttcggcggcg ccgcaccgat cgaccccgag gagttctggc gcctcgagtg
     6001 cgaattcctc gtccccgccg cgctcgaagg ccagctcacc gtcgaacgtg cgagccacgc
     6061 gcgcgcgcgc atcgtcgtcg aaggcgccaa cggcccgacc accccggccg cggacgacat
     6121 cctgcacgag cgcggcatcc tggtcgtgcc cgacgtgctc gccaacgcgg gcggcgtcac
     6181 cgtgtcctac ttcgagtggg tgcaggactt ctccagcttc ttctggaccg aggacgagat
     6241 caacgagcgc ctcgagcgca tcatggtcgc cgccttcacc gcgatctgga aggtcgcgca
     6301 ggagaagcag gtgtcgctgc gcaccgccgc cttcatcatc gcctgcgcgc gcgtgctcga
     6361 agcgcgtgcg gagcgggggc tgtatccgta aggcgggagg cgtgaggcgt cgcgcgacat
     6421 gcattcgcgc ctgacgccct tgtaggagcg ccggcaggcg cgaaagcggc cgtggagact
     6481 gcgccacggt tcggcggatt gtaggagcgc cggcaggcgc gaatgccgcc gtgggcgtgc
     6541 ccgcccgcgt cgattcccca cgcgccgctt tcgcgcctgc cggcgctcct acatgaaaca
     6601 tcgcggctcc gggccgctgg ggcgcttgcg acggcctcgc cccctcaccc accgcccgct
     6661 gcaatgcagg agcgccggca ggcgcgaaag cggccctggg gatgcgccac agatcggcgg
     6721 gtcgtaggag cgccggcagg cgcgaaagcg gcgcctggta acgtgaagcg ctgcggcggg
     6781 caggatcggc tacggcttca gccgataccc cgtgcgcagc atccaggtcg ccacgccgac
     6841 gaacaccgcg aggaagagca gcgtcatcgc caggctcacc cccaccgcca cgtcggcggt
     6901 cccgtagaag ctccagcgga agccgctcac gagatagacc accgggttga acaaggacag
     6961 cgtgcgccag gccgccggca gcatgtcgat cgagtagaag ctgccgccga ggaaggtcag
     7021 cggggtgatg atcagcagcg gcaccagctg cagcttctcg aagttgtccg cccagatgcc
     7081 gaggatgaag ccgagcaggc tgaagctgac cgcggtgagc agcaggaagc cgaccatcca
     7141 cagcgggtgc tcgatgcgca gcggcacgaa gaaggtggcg gtggcgagga tgatcaggct
     7201 caggatcacc gccttggtcg ccgccgcgcc cacgtagctg agcacgatct cgaagtgcga
     7261 caccggcgcc gacaggatct cgtagatcgt gcgcgagaac ttggggaaga agatgccgaa
     7321 ggacgcgttc gacacgctct gggtgagcag gttgagcatg atcaggccgg gcacgatgaa
     7381 ggcaccgtag ctcacccctt ccacctccgg gatgcgcgcg ccgatcgccg cgccgaacac
     7441 gacgaagtac agcgaggtgg tgatcaccgg cgccagcacg ctctgcagca gcgtgcgctt
     7501 ggtgcgtgcc atctcgaaca gatagatcgc gcggaccgcg tgccagttca tcgtgcgccc
     7561 tccccggccg gttcgcgctc gctcaccagg ctgacgaaga tctcttccag cgagcgctgg
     7621 gtggtgtgca ggtcggcgaa ggcgataccg gccgcggcga ggtcctgcag caggtcggcg
     7681 atcgcgttgt cctcggtttc cgcctcgtag cgatagacca gcgtgccgcc gcccttgccc
     7741 agcgccagcc cgtagcgcgc cagcgcgggc gggatctgcg ccagcggcgc cgccagctgc
     7801 agcgtgagct gcttgccgcc gagcttcttc atcagcgccg ccttgtcctc gaccaggatc
     7861 agcgcgccct tggcgatcac gccgatgcgg tcggccatct cctcggcctc ctcgatgtag
     7921 tgcgtggtca ggatcacggt gacgccgctg tcgcgcagcc ggcgcacgag ctgccacatg
     7981 tcgcggcgca gctccacgtc cacgccggcg gtgggctcgt cgaggaagag gatgcgcggc
     8041 tcgtgcgaca gcgccttggc gatcagcacc cggcgcttca tgccgcccga gagcatcatc
     8101 agcttggcgt ccttcttcgc ccacagcgac aggtccttga gcagctgctc gaggtaggcg
     8161 gggtcgggcg gcttgccgaa cagcccgcgc gagaagctca ccgtgttcca caccgtctcg
     8221 aaggcgtcgg tggtcagttc ctgcggcacc aggccgatga gggcgcgcgc ggcgcggtag
     8281 tcgcgcacga tgtcgtggcc gtcgacgcgc accgtgccgg cgctggcgtt gaccaggccg
     8341 cacacgacgc tgatcagcgt ggtcttgccg gcgccgttgg gacccagcag cgcgaagatc
     8401 tcgccgcggc ggatgtcgag gtcgacgccc ttcagcgcgg cgaagccgga ggcgtaggtc
     8461 ttggagaggc cggagatcga gatgatggag tccatggggt cgaagatatc agatcgccgc
     8521 ggcaccccat cgggatcgag cgcaagcgcg ggccagaaag ccgccttcgc gcctgccggc
     8581 gctcctacag aaaccgccac gtgctccgcc ccccttgtag gagctgcggc agctgcgaat
     8641 gcggcggttc ggcgaccgca gcgccgtcca gcggcgcgct gcgaccagcc gtcgggaacg
     8701 cttccgcagc gcgtgcggcg cgcgtagact cccccgcacc ccgcac
//
LOCUS       DAOTIN010000130         8708 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_9673_length_8708_cov_9.099503, whole genome shotgun sequence.
ACCESSION   DAOTIN010000130 DAOTIN010000000
VERSION     DAOTIN010000130.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 8708)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 8708)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8708
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_9673_length_8708_cov_9.099503"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1299)
                     /locus_tag="P5537_14420"
     CDS             complement(<1..1299)
                     /locus_tag="P5537_14420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004312594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 17 protein"
                     /protein_id="HRV79281.1"
                     /translation="MKNAASFAARILTAIAIAAVVAFAQYWIWQQLNRSTEFIGTNQS
                     IKGFAYNGFQRDQSPLKGTYPTRAELASDLDLLGRYSDGLRTYGVNDLPELLDLAGER
                     DMLVTAGAWIDARPDSNAREVAALIDAARKMRHIERVMVGNEAILRGDVTVGELIVYL
                     DEVRKAIRKPVSTAEPWHVWLRYPELAKHVDYITVHLLPYHEGLPVDKAVEYAFQRYD
                     EVARAHPRKKIVVGEVGWPSRGPTIDAAIPSLDNQARFVREFLAHPRTARIDYFLMEA
                     IDQPWKVDVEGWAGPYWGMFNADREPKYQLEGVVERDPHWSHKASNAAALAFIPMMLA
                     AFFLPGWSIGGRLFLAALIQACISTLIIGINVPVEYYLTQRDLIGLVLLIGATCMTAA
                     VLLSHGFEFGEVLFKKKWARRFTPLPPHPPEQQPFVSIHLA"
     gene            1604..2038
                     /locus_tag="P5537_14425"
     CDS             1604..2038
                     /locus_tag="P5537_14425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79282.1"
                     /translation="MPTNLPKHDVARPLLVGLALAALALLLRHGVLEAGLLPRDCTAA
                     DAPALACLFKQAFVHSFLDQRIGWVSLVAGALAFVRASRGLAWAGWLCGVAGLVLYSY
                     DPAAVGALLALLVLVRPHQQHGQGQGEAGEQPGDRLRVGRLA"
     gene            complement(1931..3553)
                     /locus_tag="P5537_14430"
     CDS             complement(1931..3553)
                     /locus_tag="P5537_14430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004312591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,6-glucan synthase"
                     /protein_id="HRV79283.1"
                     /translation="MIFAPRTDRSRLWLALLIASTAMLLLLAAMLWQQTRPVPMHDLH
                     LAEGEKLRCVSYAPYHRPGQTPLIEDTRIEREQIAADLAALAKITDCVRLYSIDQGLE
                     HVPELARPLGLKVLLGAWIGYEKAKNARELERAIALANANADVVRALIVGNEVLLRRE
                     RTEDEMRELIRHAKAHAQVPVTYADVWEFWTRHDSLAAEVDFVTVHILPFWEDEPVDI
                     ELALEHVAETRRHVGEHFAGKQILIGETGWPSAGRQREESRPSRVNQARYIREFVHRA
                     HAEGWDYNLIEAIDQPWKRRLEGTVGGFWGMLDADSLQPKFPLAGTVAEREGVAGPLG
                     GAAVGGVLAFLLAATGRRTRCLRASAIGAAGALGGMVAVLHWEHAHLAYRDALEWSLL
                     GGVAVLGALLPLTLARWYGEPLPDSGHAARILQRGERLRSKAASLGMLRGALLFAAAV
                     AALLLWVDPRYRDFPTLLYLVPAVVLGVIGWWRTGTTRAEITLALVILVGVVARWSSE
                     PANPQAIAWLLTGLALALPVLLVRTHQHEQRE"
     gene            complement(3704..6598)
                     /gene="gcvP"
                     /locus_tag="P5537_14435"
     CDS             complement(3704..6598)
                     /gene="gcvP"
                     /locus_tag="P5537_14435"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002945370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004375 - glycine dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase"
                     /protein_id="HRV79284.1"
                     /translation="MTDTLLSAPLARLEQRDAFVHRHLGPDAGEIARMCATIGVADVD
                     ALIEQTVPAGIRLESPLPLAGAMPEHEALARLKAIASRNVVKKSLIGQGYYGTHVPAV
                     VLRNVLENPGWYTAYTPYQAEISQGRLEALLNYQQMVIDLTGLELANASLLDEATAAA
                     EAMTMARRVSKSKSNVFFIDEACFAQTIDVVRTRAHYFGYELVYGKAAEAGSHDCFGA
                     LLQYPNARGEVVDLTAAIAELKARGAVVAVASDLMALVLLKSPGAMGADIALGSAQRF
                     GVPMGFGGPHAAFFATREGYVRSMPGRIIGVSKDARGKTALRMTLQTREQHIRREKAN
                     SNICTSQVLLANLSGFYAVYHGPQGLRTIAARIHRLAAVLAAGLREAGFGLHDRPFFD
                     TLEVEVGARAPAILRAAEEAGFNLRSVSGTTLGLSVDETTTRDDVAAILGCFGASTDV
                     SVLDTRVAAAGGALPAELLRSDAVLAHPVFNTHHTEHEMLRYLKKLQNRDLALDHSMI
                     SLGSCTMKLNATSEMIPITWPEFANIHPFAPRDQAAGYLEMIEGLADYLRAVTGFPAI
                     SMQPNSGAQGEYAGLVAIARYHASRGEANRKICLIPKSAHGTNPATAQMCGMQVVVVD
                     CDDNGNVDVADLKAKAEKHAADLAALMITYPSTHGVFEESIREICAIVHQFGGQVYMD
                     GANLNAQVGLTSPATIGADVSHMNLHKTFCIPHGGGGPGMGPIGLAAHLAPFMADHVI
                     QPTGGAGRPNLGQGAVSAAPFGSASILPISWMYIAMMGGEGLKQATEVAILNANYLAE
                     RLKDHYPVLYTGSQGRVAHECILDIRPIKAATGISEVDIAKRLMDYGFHAPTMSFPVA
                     GTIMVEPTESEDLGELERFVAAMVAIREEIRQIESGTWPAEDNPLKHAPHTQADFLGD
                     WNRPYSRAQAVFPLPWVAENKFWPSVNRIDDVYGDRNLFCACVPMSDYAE"
     gene            complement(6601..6987)
                     /gene="gcvH"
                     /locus_tag="P5537_14440"
     CDS             complement(6601..6987)
                     /gene="gcvH"
                     /locus_tag="P5537_14440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004376986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HRV79285.1"
                     /translation="MSNVPSTLKYTKSHEWVRVEDDGTLTIGVTDHAQEALGDIVFLE
                     LPEAGRALSAGESCAVIESVKAASDIYAPVAGEVVANNQDAIDAPESVNADAYSAWLF
                     KLKPANAADITALMDAAAYEAEIAQA"
     gene            complement(7109..8200)
                     /gene="gcvT"
                     /locus_tag="P5537_14445"
     CDS             complement(7109..8200)
                     /gene="gcvT"
                     /locus_tag="P5537_14445"
                     /EC_number="2.1.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004376984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004047 - aminomethyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system aminomethyltransferase
                     GcvT"
                     /protein_id="HRV79286.1"
                     /translation="MTTAAKLTPLHAAHVAAGARMVDFAGWDMPVNYGSQIEEHHAVR
                     RDAGMFDVSHMLALDLAGPDATSWLRGLLANDVAKLKDSGKALYSCMLNERGGVIDDL
                     IVYRFSDADYRIVVNAGTAEKDVAWMRQRIAATGANVTLQARRDLAMIAVQGPRAIER
                     ATAALPELSTANGVPAPFVGARVGDLLIARTGYTGEDGLEIAVPAIRAEAMWNALVAA
                     GVRPCGLGARDTLRLEAGMNLYGQDMDDDVSPLDAGLSWTVDMKDETRDFVGRAALQA
                     RPASQRLLGLILEDKGVLRSHMTVFTAAGEGETTSGSFSPSLEKSIAFARLPLASQPG
                     DAVEVDIRGKRLKARTVKLPFVRNGKALV"
     regulatory      complement(8400..8486)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
BASE COUNT         1210 a         2789 c         3287 g         1422 t
ORIGIN      
        1 ggccaggtgg atggacacga agggctgctg ctcgggcgga tgcggcggca gcggggtgaa
       61 gcggcgcgcc cacttcttct tgaacagcac ctcgccgaac tcgaagccgt gcgacagcag
      121 caccgccgcg gtcatgcagg tggcgccgat cagcagcacc aggccgatca ggtcgcgctg
      181 ggtgaggtag tactcgaccg gtacgttgat gccgatgatc agcgtcgaga tgcaggcctg
      241 gatcagcgcg gcgaggaaga ggcggccgcc gatgctccag cccggcagga agaaggcggc
      301 cagcatcatc gggatgaagg cgagcgcggc ggcgttgctg gccttgtgcg accagtgcgg
      361 gtcgcgctcg accacgccct cgagctggta cttgggctcg cggtcggcgt tgaacatgcc
      421 ccagtagggg ccggcccagc cctcgacgtc caccttccac ggctggtcga tcgcctccat
      481 gaggaagtag tcgatgcgcg cggtgcgcgg atgggcgagg aactcgcgca cgaagcgcgc
      541 ctggttgtcg agcgagggga tggcggcgtc gatggtcggg ccgcggctcg gccagccgac
      601 ctcgccgacg acgatcttct tgcgcggatg cgcgcgcgcg acctcgtcgt agcgctggaa
      661 ggcatactcc accgccttgt ccaccggcag gccctcgtgg tacggcagca ggtgcacggt
      721 gatgtagtcg acgtgcttgg cgagctcggg gtagcgcagc cacacgtgcc agggctcggc
      781 ggtggacacc ggcttgcgga tcgccttgcg aacctcgtcg agatagacga tgagctcgcc
      841 gaccgtgacg tcgccgcgca ggatggcctc gttgccgacc atgacgcgct cgatgtggcg
      901 catcttgcgt gcggcgtcga tcagcgccgc gacctcgcga gcgttggagt cggggcgggc
      961 gtcgatccag gcgccggcgg tgaccagcat gtcgcgctcg ccggcgagat cgagcagctc
     1021 gggcaggtca ttgacgccgt aggtgcgcag gccgtcggag tagcgtccga gcaggtcgag
     1081 gtcggaggcg agctcggcgc gcgtggggta ggtccccttc agcgggctct ggtcacgctg
     1141 gaagccgttg taggcgaagc ccttgatgct ctggttggtg ccgatgaact cggtgctgcg
     1201 gttgagctgc tgccagatcc agtattgcgc gaaggcgacc accgcggcga tggcgatcgc
     1261 ggtgaggatg cgggctgcga aggaggcggc gttcttcatg gtggttcctg ggcgccgtcc
     1321 tgcaggtacg acgcgggtgc attgcaaggg cctcgtgggc cgcgggtcgg agcgagcccg
     1381 ggcggatgcg gctcgcgctc cgttttggcg ctgcgctgcc gcaatcgcgg agcccgccgc
     1441 actgtgacaa aatgcgcgcg cccggcgagg cgtccgtcct tcactccgac ggcgcgcatt
     1501 ttattcgcca tttcagcccc ttacgagccg gctggggtgc caatttgcaa cactttgcac
     1561 gtcttttcgg cgtgcgctga ttttgaaggg aaagcgtatc cccatgccaa ctaatttgcc
     1621 caaacatgac gtcgcccgcc ctcttctcgt cgggctcgcc cttgccgcgc tcgcgctctt
     1681 gctgcgccac ggcgtgctcg aggccggcct gctgccgcgc gactgcacgg ccgccgacgc
     1741 gccggcactg gcatgcctgt tcaagcaggc cttcgtgcac agcttcctcg accagcgcat
     1801 cggctgggtg agcctggtcg cgggcgcgct cgccttcgtg cgcgccagcc gcggcctggc
     1861 ctgggcgggc tggctgtgcg gggtggcggg gctggtgctg tacagctacg acccggccgc
     1921 ggtcggtgcc ttactcgcgc tgctcgtgct ggtgcgtccg caccagcagc acgggcaggg
     1981 ccagggcgag gccggtgagc agccaggcga tcgcctgcgg gttggccggc tcgcttgacc
     2041 agcgcgcgac cacgccgacc aggatcacca gcgcgagggt gatctcggcg cgcgtggtgc
     2101 ccgtgcgcca ccagccgatg acgccgagca ccacggcggg gacgaggtat agcagggtgg
     2161 ggaagtcacg gtagcgcgga tcgacccaca gcagcagcgc ggccaccgcc gcggcgaaaa
     2221 gcagcgcgcc gcgcagcatg cccagcgaag cggccttgga gcgcaggcgc tcgccccgct
     2281 gcaggatgcg tgcggcgtgg ccgctgtcgg gcagcggctc gccataccag cgcgccagcg
     2341 tgagcggcag cagggcgccg agcacggcga cgccgccaag caggctccat tcgagcgcgt
     2401 cgcggtaggc caggtgggcg tgttcccagt gcagcaccgc gaccattccg ccgagcgcgc
     2461 cggctgcgcc gatcgcgctc gcgcgcaggc agcgcgtgcg ccggccggtg gccgcgagca
     2521 ggaaggcgag cacgccgccc accgccgcgc cgccgagtgg gccggccacg ccctcgcgct
     2581 cggcgaccgt gccggcgagc gggaacttgg gctgcaggct gtcggcgtcg agcatgcccc
     2641 agaagccgcc caccgtgcct tcgaggcggc gcttccaggg ctggtcgatg gcctcgatga
     2701 ggttgtagtc ccagccctcc gcgtgcgcac gatgcacgaa ctcgcggatg tagcgcgcct
     2761 gattcacccg cgagggcctg gattcctcgc gctggcggcc ggcgctcggc cagccggtct
     2821 cgccgatgag gatctgcttg ccggcgaagt gctcccctac gtgtctgcgc gtctcggcga
     2881 cgtgctcgag cgcgagctcg atgtcgaccg gctcgtcctc ccagaagggc aggatgtgca
     2941 cggtgacgaa gtcgacctcg gcggcgaggc tgtcatggcg ggtccagaac tcccacacgt
     3001 cggcgtaggt caccggcacc tgcgcgtgcg ccttggcgtg acggatgagc tcgcgcatct
     3061 cgtcctcggt gcgctcgcgg cgcagcagga cctcgttgcc gacgatgagc gcgcgcacga
     3121 cgtcggcgtt ggcgttggcg agcgcgatcg cgcgctcgag ctcgcgcgcg ttcttcgcct
     3181 tctcgtagcc gatccaggcg ccgagcagca ccttgaggcc gagcgggcgg gcgagctcgg
     3241 ggacgtgctc gaggccctgg tcgatcgagt acaggcgtac gcagtcggtg atcttcgcca
     3301 gcgcggcgag gtcggcggcg atctgctcgc gctcgatgcg ggtgtcctcg atcagcgggg
     3361 tctggccggg gcggtgatac ggcgcgtagg acacgcagcg cagcttctcg ccttcggcga
     3421 ggtgcaggtc gtgcatgggc accgggcgcg tctgctgcca cagcatggcg gcgagcagca
     3481 gcagcatggc ggtgctggcg atgagcaggg cgagccagag gcggctgcgg tcggtgcgtg
     3541 gagcgaagat caccgtgtcc ggttccttcc aggttcgggt ggaggcgcgg ggcgacgccg
     3601 aatgtatgca aaaaaagagc cacgcccgcg ggcgtggctc ctgcctccga ggctggcgga
     3661 ttctaccagc gctcggggcc tcgttcgccg ctgcgggcgg cgcttactcg gcgtagtcgc
     3721 tcatcggcac gcaggcgcag aacaggttgc ggtcgccata gacatcgtcg atgcgattga
     3781 cgctgggcca gaacttgttc tcggccaccc agggcagcgg gaacaccgcc tgcgcgcgcg
     3841 agtagggccg gttccagtcg ccgaggaagt cggcctgggt gtgcggcgcg tgcttgagcg
     3901 ggttgtcctc ggcgggccag gtgccggact cgatctggcg gatttcctca cggatcgcca
     3961 ccatcgcggc gacgaagcgc tcgagctcgc cgaggtcttc cgactcggtc ggctcgacca
     4021 tgatcgtgcc ggccaccggg aaggacatgg tcggcgcgtg gaagccgtag tccatcaggc
     4081 gcttggcgat gtcgacctcg gagatgccgg tcgccgcctt gatcgggcgg atgtcgagga
     4141 tgcactcgtg cgcgacgcgg ccctggctac cggtgtacag caccgggtag tggtccttga
     4201 ggcgctcggc cagatagttg gcgttgagga tcgccacctc ggtcgcctgc ttgaggccct
     4261 cgccgcccat catcgcgatg tacatccacg aaatcggcag gatgctcgcc gaaccgaagg
     4321 gcgccgccga gaccgcgccc tggcccaggt tgggccggcc ggcgccgccg gtgggctgga
     4381 tcacgtggtc ggccatgaag ggcgcgaggt gcgccgccag gccgatcggc cccatgcccg
     4441 gaccgccgcc gccgtgcggg atgcagaagg tcttgtgcag gttcatgtgc gacacgtcgg
     4501 cgccgatcgt tgccggcgag gtcaggccga cctgggcgtt gaggttggcg ccgtccatgt
     4561 acacctggcc gccgaactgg tggacgatgg cgcagatctc gcggatcgac tcctcgaaca
     4621 ccccgtgggt ggacgggtag gtgatcatca gcgcggccag gtcggcggcg tgcttctccg
     4681 ccttggcctt gaggtcggcg acgtcgacgt tgccgttgtc gtcgcagtcg accaccacca
     4741 cctgcatgcc gcacatctgc gcggtcgcag ggttggtgcc gtgagcggac ttcgggatca
     4801 ggcagatctt gcggttggcc tcgccgcggc tggcgtggta gcgcgcgatc gccaccaggc
     4861 cggcgtactc gccctgggcg cccgagttcg gctgcatgct gatcgccggg aagccggtga
     4921 ccgcgcgcag gtaatcggcc aggccctcga tcatctcgag gtagcctgcg gcctggtcgc
     4981 gcggcgcgaa cgggtggatg ttggcgaact ccggccaggt gatcgggatc atctcgctgg
     5041 tcgcgttgag cttcatcgtg cacgagccga gcgagatcat cgagtggtcg agcgcgaggt
     5101 cgcggttctg cagcttcttg aggtagcgca gcatctcgtg ctcggtgtgg tgcgtgttga
     5161 acaccgggtg ggcgagcacg gcgtcgctgc gcagcagctc cgcgggcagc gcgccgcctg
     5221 cggccgcgac gcgggtgtcg agcacgctga cgtcggtgga cgcgccgaag cagccgagga
     5281 ttgcggcgac gtcgtcgcgg gtggtggtct catccaccga caggccgagc gtggtgccgg
     5341 agacgctgcg cagattgaag cctgcttcct cggccgcgcg caggatggca ggcgcgcggg
     5401 cgcccacctc gacttcgagg gtgtcgaaga aggggcggtc gtgaaggccg aagccggcct
     5461 cgcgcaggcc ggcggcgagc accgcggcga ggcggtggat gcgtgcggcg atggtgcgca
     5521 ggccctgcgg accgtgatac acggcgtaga agccggagag gttggcgagc agcacctgcg
     5581 aggtgcagat gttggagttc gccttctcgc ggcggatgtg ctgctcgcgg gtctgcagcg
     5641 tcatgcgcag cgcggtcttg ccgcgcgcgt ccttggagac gccgatgatg cggcccggca
     5701 tcgagcgcac gtagccttcg cgggtggcga agaaggcggc gtgcgggccg ccgaagccca
     5761 tcggcacgcc gaagcgctgc gccgaaccga gggcgatgtc ggcgcccatg gcgcctgggc
     5821 tcttgagcag caccagcgcc atgaggtcgc tggcgaccgc gaccacggcg cccctggcct
     5881 tgagctcggc gatcgctgcg gtgaggtcga cgacctcgcc gcgcgcgttc gggtactgca
     5941 gcagcgcgcc gaagcagtcg tggctgccgg cctcggcggc cttgccgtaa acgagctcgt
     6001 agccgaagta atgggcgcgg gtgcgcacca cgtcgatggt ctgcgcgaag caggcctcgt
     6061 cgatgaagaa cacgttcgac ttcgacttcg acacgcggcg cgccatcgtc atcgcctcgg
     6121 cagcggcggt ggcttcgtcg agcagggagg cgttggcgag ctccaggccg gtgaggtcga
     6181 tcaccatctg ctggtagttc agcagggctt cgaggcggcc ctgggagatc tccgcctgat
     6241 agggcgtgta ggcggtgtac cagcccgggt tctcgagcac gttgcgcagc acgaccgcgg
     6301 ggacgtgggt gccgtagtag ccctggccga tcagggactt cttcaccacg ttgcggctgg
     6361 cgatcgcctt caggcgggcg agtgcctcgt gctcgggcat cgcgccggcg agcggcagcg
     6421 gcgactcgag gcggatgccg gcgggcacgg tctgctcgat cagggcgtcg acgtcggcga
     6481 cgccgatggt cgcgcacatg cgtgcgatct cgccggcatc ggggccgagg tggcggtgga
     6541 cgaaggcgtc gcgctgctcg aggcgggcga gcggggcgga aagcagggtg tcggtcatgg
     6601 tcaggcctgg gcgatttccg cttcgtaggc cgcggcgtcc atcagcgcag tgatgtcggc
     6661 ggcgttggcc ggcttgagct tgaacagcca ggccgagtag gcgtcggcgt tgacgctctc
     6721 gggggcgtcg atcgcatcct ggttgttggc gaccacttca ccagccacgg gggcgtagat
     6781 gtcggaggcg gccttgaccg actcgatcac cgcgcaggat tcgccagcgg acagcgcgcg
     6841 gccggcttcg ggcagctcga ggaagacgat gtcgccgagg gcttcctggg cgtggtcggt
     6901 gacgccgatg gtcagggtgc cgtcgtcctc gacgcggacc cattcgtggg acttggtgta
     6961 cttgagggtg ctggggacgt tgctcatggt gttctccggt cgggaaggtg ggggcgggaa
     7021 gtgtggcgaa atgcgtgctt gcgtccgctt cgtcgatcgc ttgcggacgc ggtgagaggg
     7081 cggccggggg cagccctcgt gtttcggttc agacgagcgc cttgccgttg cgtacgaagg
     7141 gcagcttgac ggtgcgcgcc ttcaggcgct tgccgcggat gtcgacctcg acggcgtctc
     7201 caggctggct ggcgagcggg aggcgcgcga aggcgatcga tttctccagg gagggagaga
     7261 agctgccgct cgtggtctcg ccctcgccgg cggcggtgaa gaccgtcatg tgcgagcgca
     7321 gcacgccctt gtcctcgagg atcaggccga gcaggcgctg gctggccggc ctggcctgca
     7381 gcgcggcgcg accgacgaag tcgcgggtct cgtccttcat gtccaccgtc cacgacagcc
     7441 cggcgtccag gggagagaca tcgtcgtcca tgtcctggcc atagaggttc atgccggctt
     7501 cgaggcgcag ggtgtcgcgc gcgcccaggc cgcagggacg cacgccggcg gcgacgagcg
     7561 cgttccacat cgcttcggcg cggatggcgg ggacggcgat ctccaggccg tcctcgccgg
     7621 tgtagccggt gcgggcgatc agcaggtcgc ccacgcgcgc gcccacgaag ggagccggca
     7681 cgccgttggc ggtggagagt tctggcaggg cggcggtggc gcgctcgatc gcgcgcggac
     7741 cctggacggc gatcatcgcc aggtcgcggc gcgcctgcag ggtcacgttg gcgcccgtgg
     7801 cggcgatgcg ctggcgcatc caggcgacgt ccttttccgc ggtgccggcg ttcacgacga
     7861 tgcgatagtc ggcatcgctg aagcggtaga cgatgaggtc gtcgatcacg ccgccacgct
     7921 cgttgagcat gcaggagtag agcgccttgc cgctgtcctt gagcttggcg acgtcattgg
     7981 cgagcaggcc gcggagccag gaggtggcgt cggggccggc gaggtcaagg gcgagcatgt
     8041 gcgagacgtc gaacatgccg gcgtcgcgac gcaccgcgtg atgctcctcg atctgcgaac
     8101 cgtagttcac cggcatgtcc cagccggcga aatcgaccat gcgtgcgccg gcggcgacgt
     8161 gggcggcgtg gaggggggtc agcttggcag cggtagtcat cgcgtaggcg ctccgtcagg
     8221 gtgaacgaaa aaggggcgga tacggctcct cgccgcgcac gccccatctg tccttttacc
     8281 tgagagattt tccgtggccg cgcggcagcc tctatatata taggtgctga ggcggatgac
     8341 ggtgtgcccc ttcggtgggt acgccggcgc cctgcgcccg taccgctctc cagacttttg
     8401 ctgcgcacgc ggtccttttg cctgagcggt tccgggggtt gcgccttcgg cgactccatc
     8461 gaggagttct ctcccgcgtg tcgcgcggac gataacactt gccccggccg agccgcaacc
     8521 gtgacggagg cattgtcggc tgccctcgca ggctccatct tgcgcgcccc ttgctcgcca
     8581 gcgtctgccg tagcaccggc gccgaggagc gctgcatggc gccgcgtctg cactggggcg
     8641 gatcgccgcc tgcgcgccgc attctcgccc gtctgcactg cggacttcaa tgcagcggtt
     8701 cctgcagg
//
LOCUS       DAOTIN010000131         8670 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_9748_length_8670_cov_9.368891, whole genome shotgun sequence.
ACCESSION   DAOTIN010000131 DAOTIN010000000
VERSION     DAOTIN010000131.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 8670)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 8670)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8670
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_9748_length_8670_cov_9.368891"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..434)
                     /locus_tag="P5537_14450"
     CDS             complement(<1..434)
                     /locus_tag="P5537_14450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase subunit gamma"
                     /protein_id="HRV79287.1"
                     /translation="MTTPSMRVRHGGWLAVLLLALMLWAVALPLQAAEPPPGSSAADQ
                     AQRQVERPLNNAPVWRAVRSGEEHFTTVRGPEAGVLIQSEGNTWRQLRNGPLTLYGGW
                     LLILVPSAILLFWLIKGTMKLHGARTGRKMLRFSGFERFVHWG"
     gene            complement(445..678)
                     /locus_tag="P5537_14455"
     CDS             complement(445..678)
                     /locus_tag="P5537_14455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018989265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79288.1"
                     /translation="MSSTLKSIALAALAGSTLLGLSACSEVPQVTVYEQGQYRGKADT
                     RPWEGGEFKGDRAAWEKALKERARGQNEYNRIQ"
     gene            complement(675..1301)
                     /gene="fdh3B"
                     /locus_tag="P5537_14460"
     CDS             complement(675..1301)
                     /gene="fdh3B"
                     /locus_tag="P5537_14460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004374274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase FDH3 subunit beta"
                     /protein_id="HRV79289.1"
                     /translation="MGRMKFLCDAERCIECNGCVTACKNEHEVPWGVNRRRVVTMNDG
                     VPGERSISVACMHCSDAPCMAVCPTDCFYKTEDGVVLHDKDKCIGCGYCFFACPFGAP
                     QFPNGPAAFGARGKMDKCTFCAGGPEETGSAAEYEKYGSNRLAQGKLPLCAEMCSTKA
                     LIAGDADVVANIFRERVLRRGTGAEVWGWDAAYGGGERKQERKREGQS"
     gene            complement(1320..4232)
                     /locus_tag="P5537_14465"
     CDS             complement(1320..4232)
                     /locus_tag="P5537_14465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002930367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="HRV79290.1"
                     /translation="MLTKKSATAATSARRLRGAAARQLGQTMDRRAFLKRSGLGVGAG
                     ALAAQLPYNFIGAAEAAAPAGASRAEGKAEVRRTVCTHCSVGCASDAIVRNGVWVHQE
                     PVFDSPINLGSHCAKGAALREHGHGEYRLKYPMKLVDGKYQKISWEQALNEVGDRLLK
                     IREESGPDAVYFIGSSKHNNEQAYLLRKFVSFWGTNNTDHQARICHSTTVAGVANTWG
                     YGAMTNSYNDMQNAKAMLFIGSNAAEAHPVSLLHILHAKENGAKMIVVDPRFTRTAAK
                     AHQYIRIRSGTDVPFLFGLLYHIFQNGWEDKQYIDDRVFGMDKIREEVLAKWTPDKVE
                     EACGVPEDQMLLAARTMAENRPSTIVWCMGQTQHTIGNAMVRASCILQLALGNIGKSG
                     GGANIFRGHDNVQGATDVGPNPDSLPGYYGLATGSWKHWCSVWGVDYEWVKGRYASQA
                     MMEKSGITVSRWIDGVLENKELIDQPAGNLRAVVYWGHAPNSQTRGAEMVEAMKALDT
                     LVVIDPYPSATASMAAMVRKDGVYLLPACTQFETTGSCTASNRSLQWREKVIEPLFES
                     KPDHTIMYAFAKKFGWGEQFVKNIKLEKDAQGWDEPSMEDTLREINRGTWTIGYTGQS
                     PERLKLHMKNMHTFDVKTLKAVGGPCDGEYFGLPWPCFGTPEMKHPGTPNLYDTSKHV
                     MDGGGNFRANFGVEKDGVSLLAGEGSASKGADLQMGYPEFDHVLLKKLGWWDELTEAE
                     KAAAEGKNWKTDLSGGIQRVVMKNHGCHPFGNARARAVVWNFPDPVPQHREPIYSPRP
                     DLVAKYPTHDDKMKFWRLPTLYKSMQEKVKDISKDYPLVMTSGRLVEYEGGGEETRSN
                     PWLAELQQEMFAEVNPKDANDAGFRNGEYIWVESPTKARLKVRAQVTQRVAPGTVFLP
                     FHFSGWWQGKDMLEWYPEGAAPVVRGEAVNTATTYGYDSVTMMQETKTTLCRVSKA"
     gene            complement(4246..4452)
                     /locus_tag="P5537_14470"
     CDS             complement(4246..4452)
                     /locus_tag="P5537_14470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004374280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocation signal
                     domain-containing protein"
                     /protein_id="HRV79291.1"
                     /translation="MKDENTKLSRRNFLAAIGAGGAAGAAALAATAAQATPVTAKVVE
                     EARREVADQGVSAHMRNYYRTTRI"
     gene            complement(4521..5159)
                     /locus_tag="P5537_14475"
     CDS             complement(4521..5159)
                     /locus_tag="P5537_14475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone TorD family protein"
                     /protein_id="HRV79292.1"
                     /translation="MKDAAISIQPQPTWSDEDRARAEHYALIARLFHAAPDDALLAAL
                     AQAGGTLGGEGGELPRAWAALGAAAQAMPAQAVADEFDALFVSVGKPEVMCNGSWYLT
                     GFLQEEPLAELRDDLAELGLGRRAGVTETEDHIAALAEVMRHLVLTGPDAAGLERQRR
                     FFGRHLAPWYAQFAGALAVVPGADFYAKVGDLLAAFMDIEREAFDMLEAEAR"
     gene            complement(5170..7278)
                     /locus_tag="P5537_14480"
     CDS             complement(5170..7278)
                     /locus_tag="P5537_14480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004384343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HRV79293.1"
                     /translation="MSERHDPTARIHLCDCNRSFVLDAGRLAANAGATVQCHHALCAG
                     ELPALDASLASGQAVLVACTQETALFGELAEEAGAGERIRFFNLRENAGWSSEAAAAT
                     PKLAALIAAATTLADPEPVPAVQMAAGRSLLIVGEAGAALGWAERLAGSFEPAVLITA
                     RTQDAELPAVNAYPVWSGKPVALSGHLGAYELEWTQQNPIDLELCVRCNACVKACPEA
                     AIGWDLQVDVDACRSHRACVAACGEIGAIDFARADVVRRERFDLVLDLSTEPLLKRVE
                     LPDGYAAPGRDPFEQALAVQALGEFVGEFEKPRYVAFEAGLCAHSRAKKTGCTNCIEA
                     CATAAIRSQGDVIAVDPWLCKGCGTCSTVCPSGALSFQYPRVPELGQRVKTLLAEYAR
                     AGGSDACVLFHSAAAGDATIARLARRGRGLPARVIPVEVWSADAVGLDLMLGSLALGA
                     CQVAVLAAGSHDAAPLQAQAGHGQVILSALGYGGEHLRVIEADADDWQALERALHDWA
                     PAIGVAEPARFQLLPKKRETLDFALRHLVAHAPAAHTPAGLPATIALKTGAPFGQVLV
                     SDACTLCMSCTGACPAGALRAASDAYRLEFVEKNCLQCGLCEVSCPESAITLEPRLLL
                     GEDARKARALREADVFHCTACGKAMGAAPLIESMIARLSGHSMFAGEAERARLRMCAD
                     CRVIDMMKAGSAVKAWDLTE"
     gene            complement(7407..8051)
                     /locus_tag="P5537_14485"
     CDS             complement(7407..8051)
                     /locus_tag="P5537_14485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002930361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3306 domain-containing protein"
                     /protein_id="HRV79294.1"
                     /translation="MSGGFLSRWSRRKLAAVAQAEAVVPVAGESPAPLRSEAADPLSV
                     VPAAPDGAASAETLAGAAAEAGLPPVESLSLSSDFTAFLKDEVSEALRRKALHKLFSD
                     PHFNQMDGLDIYIDDYSRPDPIPPEILAKLQHAREWLADDAAAGPAPDGATELVDAVP
                     VDHEGGQAATAAEAASAQGRSAQAADASDGRCGDELAAGEAASESQQEPGQNAP"
     gene            complement(8048..8515)
                     /locus_tag="P5537_14490"
     CDS             complement(8048..8515)
                     /locus_tag="P5537_14490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004291591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3305 domain-containing protein"
                     /protein_id="HRV79295.1"
                     /translation="MKEFPIAVIMERRRLNNPWVDAAWEAVGVVPAFDDAEPAPRRIV
                     DEPERSQWRCGGFALELFRDEAENYFANLSAPIPKVFVLWRMDGEFARPATVSVSYGE
                     AARWLDSGEQVDGVAMSREIADWVGDFVNIHYKPEPKKKAKRNDPLGLDRRRA"
BASE COUNT         1256 a         3069 c         2965 g         1380 t
ORIGIN      
        1 ccccagtgca cgaagcgctc gaagcccgag aagcgcagca tcttgcgccc ggtcctggca
       61 ccgtgcagct tcatcgtgcc cttgatcagc cagaacagca ggatggccga aggcacgagg
      121 atgagcagcc agccgccgta cagcgtgagc gggccattac gcagctggcg ccaggtgttg
      181 ccctcgctct ggatcagcac gccggcctcg gggccacgca cggtggtgaa gtgctcctcg
      241 ccggagcgca ccgcgcgcca caccggcgcg ttgttgagcg gccgctcgac ctggcgctgg
      301 gcctggtccg cggcgctgct gccgggcggc ggttcggccg cctgcagcgg cagcgccacc
      361 gcccacagca tgagcgcgag caacagcacg gccagccagc cgccgtgccg cacccgcatc
      421 gatggtgtcg tcatggcgct ctcctcactg gatgcggttg tactcgttct ggccgcgggc
      481 gcgctccttg agcgccttct cccaggccgc acggtcgccc ttgaactcgc cgccctccca
      541 ggggcgggtg tcggccttgc cgcggtactg gccctgctcg tagacggtga cctgcggcac
      601 ctcgctgcag gcggacaggc cgagcagcgt gctgccggcc agcgcggcga gcgcgatcga
      661 cttcagcgtg ctgctcatga ctgcccctcc cgcttgcgtt cctgcttgcg ctcgccgccg
      721 ccataggcgg cgtcccagcc ccacacctcg gcgccggtgc cgcggcgcag cacgcgctcg
      781 cggaagatgt tggccaccac gtcggcatcc ccggcgatca gcgccttggt cgagcacatc
      841 tcggcgcaca gcggcaactt gccctgggcg aggcggttgg agccgtactt ctcgtactcg
      901 gcggccgaac cggtctcttc cgggccgccg gcgcagaagg tgcacttgtc catcttgccg
      961 cgcgcgccga aggccgccgg gccattgggg aactgcggcg cgccgaacgg acaggcgaag
     1021 aagcagtagc cacagccgat gcacttgtcc ttgtcgtgca gcaccacgcc gtcttcggtc
     1081 ttgtagaagc agtcggtcgg gcacaccgcc atgcacggcg cgtccgagca gtgcatgcag
     1141 gccaccgaga tcgagcgctc gcccggcacg ccgtcgttca tcgtcaccac ccggcggcgg
     1201 ttcacgcccc agggcacctc gtgctcgttc ttgcacgcgg tgacgcagcc gttgcattcg
     1261 atgcagcgct cggcgtcaca gagaaatttc atgcgtccca tcgtgttctc tcctcgtcct
     1321 tacgccttgc tcacgcggca cagggtggtc ttggtttcct gcatcatggt caccgagtcg
     1381 tagccgtagg tcgtggcggt gttgaccgcc tcgccacgca cgaccggcgc cgcaccctcg
     1441 gggtaccact cgagcatgtc cttgccctgc caccagccgg agaagtggaa aggcaggaag
     1501 accgtgcccg gcgccacgcg ctgggtgacc tgggcgcgca ccttgaggcg ggccttggtg
     1561 ggtgactcga cccagatgta ctcgccgttg cggaagcccg cgtcgttggc gtccttcggg
     1621 ttcacctcgg cgaacatctc ctgctgcagc tcggccagcc aggggttgga gcgcgtctcc
     1681 tcgccgccgc cctcgtactc gaccaggcgg ccggaggtca tcaccagcgg atagtccttg
     1741 gagatgtcct tcaccttctc ctgcatcgac ttgtacaggg tgggcaggcg ccagaacttc
     1801 atcttgtcgt cgtgggtcgg gtacttggcg accaggtccg ggcgcggcga gtagatcggc
     1861 tcgcggtgct gcgggacggg gtcggggaag ttccacacca cggcgcgcgc gcgcgcgttg
     1921 ccgaaggggt ggcagccgtg gttcttcatc accacgcgct ggatgccacc ggacagatcg
     1981 gtcttccagt tcttgccctc ggcagcggcc ttctcggcct cggtgagttc gtcccaccag
     2041 cccagcttct tgagcagcac gtggtcgaac tcggggtagc ccatctgcag gtccgcgccc
     2101 ttggaggccg agccctcgcc ggcgagcagc gacacgccat ccttctcgac gccgaagttg
     2161 gcgcggaagt tgccgccgcc gtccatgaca tgcttggagg tgtcgtacag gttgggcgtg
     2221 cccgggtgct tcatctcggg ggtgccgaag cacggccagg gcagcccgaa gtattcgccg
     2281 tcgcagggcc cgcccaccgc cttcagcgtc ttcacgtcga aggtgtgcat gttcttcatg
     2341 tgcagcttga ggcgctcggg cgactggccg gtgtagccga tggtccaggt gccgcggttg
     2401 atctcgcgca gcgtgtcctc catgctcggc tcgtcccagc cctgggcgtc cttctcgagc
     2461 ttgatgttct tcacgaactg ctcgccccag ccgaacttct tcgcgaaggc gtacatgatg
     2521 gtgtggtcgg gcttggactc gaacagcggc tcgatgacct tctcgcgcca ctgcagcgag
     2581 cggttcgatg cggtacacga acccgtggtc tcgaactggg tgcaggccgg cagcaggtag
     2641 acgccgtcct tcctgaccat cgccgccatc gacgcggtgg ccgacgggta gggatcgatc
     2701 accaccaggg tgtcgagcgc cttcatcgcc tcgaccatct cggcgccgcg cgtctgcgaa
     2761 ttgggcgcgt ggccccaata aaccactgcg cgcaggttgc cggcgggctg gtcgatgagc
     2821 tccttgttct cgagcacgcc gtcgatccag cgcgacacgg tgatgccgga cttctccatc
     2881 atcgcctgcg aggcgtagcg ccccttgacc cactcgtagt ccacgcccca cacgctgcac
     2941 cagtgcttcc acgagccggt cgcgaggccg tagtagccgg ggagcgagtc ggggttgggg
     3001 ccgacgtcgg tcgcgccctg cacgttgtcg tggccgcgga agatgttggc gcccccaccc
     3061 gacttgccga tgttgccgag cgcgagctgc aggatgcacg aggcgcgcac catcgcattg
     3121 ccgatggtgt gctgggtctg gcccatgcac cagacgatgg tgctcgggcg gttctcggcc
     3181 atggtgcgtg cggccagcag catctggtcc tcgggcacgc cgcaggcctc ttccaccttg
     3241 tccggcgtcc acttggcgag cacctcctcg cggatcttgt ccatgccgaa gacgcggtcg
     3301 tcgatgtact gcttgtcttc ccagccgttc tggaagatgt ggtacagcag gccgaacagg
     3361 aagggcacgt cggtgcccga gcggatacgg atgtactggt gggccttggc cgcggtgcgg
     3421 gtgaagcgcg gatccaccac gatcatcttc gcgccgttct ccttggcgtg caggatgtgc
     3481 agcagcgaca ccgggtgcgc ctcggccgcg ttcgagccga tgaacagcat cgccttggcg
     3541 ttctgcatgt cgttgtagga gttcgtcatc gcgccgtaac cccaggtgtt cgccacgccc
     3601 gccacggtgg tggagtggca gatgcgcgcc tggtggtcgg tgttgttggt gccccagaag
     3661 gagacgaact tgcgcagcag ataggcctgc tcgttgttgt gcttcgacga gccgatgaag
     3721 tacaccgcgt cgggaccgga ctcctcgcgg atcttcagca agcggtcgcc gacctcgttg
     3781 agggcctgtt cccacgagat cttctggtat ttgccatcga ccagcttcat cgggtacttg
     3841 aggcggtatt cgccgtgacc gtgctcgcgc agcgccgcgc ccttggcgca gtgcgaaccg
     3901 aggttgatcg gcgagtcgaa caccggctcc tggtgcaccc acacgccatt gcgcacgatg
     3961 gcatcactgg cacagcccac cgaacagtgg gtgcacacgg tgcggcgcac ctcggccttg
     4021 ccttcggcgc gcgaggcgcc cgcgggcgcg gcggcctcgg cggcgccgat gaagttgtag
     4081 ggcagctggg cggcgagcgc gccggcgccc acgcccaggc cggagcgctt gaggaaggcg
     4141 cggcggtcca tggtctggcc gagctggcgc gcggcggcac cacgcaggcg acgcgcgctg
     4201 gtggctgcgg tcgcggattt cttcgtcaac atcctcgcgt cctcctcaga tccgcgtcgt
     4261 gcggtagtag ttgcgcatgt gcgcgctcac gccctgatcg gcgacctcac ggcgcgcttc
     4321 ctcgaccacc ttggcggtga ccggcgtggc ctgcgcggcg gtggcggcca gcgcggcagc
     4381 gccggctgcc ccgccggcac cgatcgcggc caggaagttg cggcgcgaca gcttggtgtt
     4441 ttcgtccttc atcctcgctc tcccctctat gcgccggagc ggctcgtgcc ggcccggcct
     4501 cgtttccatg gcggccgcgc tcagcgcgct tccgcctcca gcatgtcgaa cgcctcgcgc
     4561 tcgatgtcca tgaaggccgc cagcaggtcg ccgaccttcg cgtagaaatc cgcccccggt
     4621 accaccgcca gcgcgccggc gaactgcgca taccaaggcg cgagatggcg cccgaagaag
     4681 cgccgctggc gctccagccc cgcggcgtcc ggcccggtca acaccagatg gcgcatgacc
     4741 tcggcgagcg cggcgatgtg gtcctcggtc tcggtgacgc ccgcccgacg gccgaggccg
     4801 agttcggcga ggtcgtcgcg cagctcggcg agcggctctt cctgcaggaa gccggtgagg
     4861 taccaggagc cgttgcacat gacctcgggc ttgccgaccg acacgaagag cgcatcgaac
     4921 tcgtcggcca ccgcctgcgc cggcatcgcc tgcgccgcgg cgcccagggc ggcccaggca
     4981 cgtggcaact cgccgccctc gccgccgagc gtcccgccgg cctgcgcgag cgccgccagc
     5041 agcgcgtcgt cgggcgcggc gtggaacagg cgggcgatca gcgcgtagtg ctcggcgcgc
     5101 gcgcgatcct cgtccgacca ggtcggctgc ggctgaatgg agatggcggc gtctttcatt
     5161 cggagtcgtt cattcagtga ggtcccaggc cttcacggcg gatccggcct tcatcatgtc
     5221 gatcacccgg cagtcggcgc acatgcgcag gcgcgcacgc tcggcctcgc cggcgaacat
     5281 cgagtggccg gacaggcggg cgatcatgga ttcgatcagc ggcgcggcgc ccatggcctt
     5341 gccgcaggcg gtgcagtgga agacgtcggc ctcgcgcagc gcgcgggcct tgcgtgcgtc
     5401 ctcgccaagg agcagacgtg gctcgagggt gatcgccgac tccggacagg agacctcgca
     5461 cagcccgcac tgcaggcagt tcttctcgac gaactcgagc cggtaggcat cgctcgcggc
     5521 gcgcagggcg ccggccggac aggcgccggt acaggacatg cacagcgtac aggcgtccga
     5581 caccagcacc tggccgaagg gcgcgccggt cttcaaggcg atcgtagcgg gcagcccggc
     5641 aggcgtgtgt gccgccgggg cgtgcgcgac caggtggcgc agcgcgaagt ccagcgtctc
     5701 gcgcttcttc ggcagcaact ggaagcgcgc cggctcggca acgccgatcg ccggcgccca
     5761 gtcgtggagc gcacgctcga gcgcctgcca gtcgtcggcg tcggcctcga tcacgcgcag
     5821 gtgctcaccg ccatagccga gcgcggagag gatgacctgg ccgtggcccg cctgcgcctg
     5881 cagcggcgcg gcgtcgtggc tgccagcggc gagcaccgca acctggcagg cgccgagcgc
     5941 gagactgccg agcatcaggt ccagcccgac cgcgtccgca ctccacacct cgaccgggat
     6001 cacccgcgcc ggcaggccgc ggccgcggcg agccaggcgc gcgatggtcg cgtcgccggc
     6061 cgcggcggag tggaacagca cgcaggcatc gctgccaccg gcgcgggcgt actcggcgag
     6121 cagggtcttc acgcgctggc cgagctcggg cacgcgcgga tactggaagg acagcgcgcc
     6181 cgaggggcac accgtgctgc aggtgccgca gcccttgcac agccagggat cgaccgcgat
     6241 cacgtcgccc tggctacgga tcgccgcggt ggcacaggcc tcgatgcagt tcgtgcagcc
     6301 ggtcttcttg gcccggctgt gcgcgcacag gccggcctcg aaggccacgt agcgcggctt
     6361 ctcgaactcg ccgacgaact cgcccagggc ctgcaccgcg agcgcctgct cgaaggggtc
     6421 gcgccccggc gcggcatagc cgtcggggag ttcaacacgc ttgaggagcg gctcggtgga
     6481 gaggtcgagc acgaggtcga agcgctcgcg gcgcaccacg tcggcgcgcg cgaagtcgat
     6541 cgcgccgatc tcgccacagg cggcgacgca ggcgcgatgg ctgcgacagg cgtcgacatc
     6601 gacctgcagg tcccagccga tcgcagcctc gggacaggcc ttgacgcagg cgttgcagcg
     6661 cacgcacagc tcgaggtcga tcgggttctg ctgcgtccat tcgagctcgt aggcgccgag
     6721 gtggccggag agcgccactg gcttgcctga ccacaccggg taggcattga ccgcgggcag
     6781 ctccgcatcc tgcgtgcgcg cagtgatcag caccgccggc tcgaagctgc cggccaggcg
     6841 ctccgcccaa cccagcgccg cgcctgcctc gccgacgatc aggaggctgc gtccggccgc
     6901 catctgcacc gcgggcaccg gctcgggatc ggccagcgtg gtcgcggcgg cgatcagcgc
     6961 ggcgagcttg ggggtcgccg cagcagcctc ggacgaccag ccggcgttct cgcgcaggtt
     7021 gaagaagcgg atgcgctcgc ctgcgccggc ctcctcggcc agctcgccga agagcgcggt
     7081 ctcctgcgta caggcgacaa gcacggcctg tccgctggcg agcgaagcat cgagcgcggg
     7141 gagctcgccg gcgcacagcg cgtgatgaca ctgcaccgtg gcgcccgcgt tcgcagcaag
     7201 gcgcccggcg tcgagcacga agctgcggtt gcagtcgcac aggtggatac gggcagtcgg
     7261 gtcgtggcgt tcgctcatgt gtttttccat cgattccctt aagcaaagca cttcataggc
     7321 cagccgcgac cgcaggaaaa accgcgggaa tcaccgaaaa ggcatgacca agcgataccg
     7381 gaaacccacg cgcgacaatt tgtcgctcag ggtgcgtttt gtcccggctc ttgctgcgac
     7441 tccgacgctg cctcgcccgc cgccagctcg tcgccgcatc gtccatccga agcgtccgcg
     7501 gcttgcgccg accttccctg cgcggaagcg gcctccgccg cagtagccgc ctgcccccct
     7561 tcgtggtcga cgggcaccgc gtcgacgagc tccgtcgcgc catcgggagc gggtcctgcc
     7621 gcggcgtcgt ccgccagcca ttcgcgcgca tgctggagct tggccaggat ctccggcggg
     7681 atcgggtcgg gccgggagta gtcgtcgatg tagatgtcca gcccgtccat ctggttgaag
     7741 tgcgggtcgg agaacagctt gtgcagggcc ttgcggcgca gcgcctcgct cacctcgtcc
     7801 ttcaggaagg cggtgaagtc ggaagacagc gacagactct cgaccggcgg caagcccgcc
     7861 tcggccgcgg cgcccgccag cgtctccgcc gaggcagctc catccggagc ggcgggcacg
     7921 accgaaagcg gatccgcagc ctccgaccgc agcggcgcgg gcgactcgcc cgccaccggc
     7981 accacggcct cggcctgtgc caccgcggcg agcttgcgcc gcgaccagcg cgagagaaaa
     8041 ccgccgctca cgcccgcctc cggtccagcc cgagcggatc gttgcgcttc gccttcttct
     8101 tgggctccgg cttgtagtgg atgttcacga aatcccccac ccagtcggcg atctcgcgcg
     8161 acatcgccac cccatcgacc tgctcgcccg agtccagcca gcgcgccgcc tcgccgtagc
     8221 tcaccgacac cgtcgccggc cgggcgaact cgccgtccat gcgccacagc acgaagacct
     8281 tggggatggg cgcggaaagg ttggcgaagt agttttccgc ctcgtcgcgg aagagctcga
     8341 gcgcgaagcc cccgcagcgc cactggctgc gctcgggctc gtcgacgatg cggcgcggcg
     8401 ccggctcggc gtcgtcgaag gccggcacca cccccaccgc ctcccaggcg gcgtcgaccc
     8461 aggggttgtt caggcggcgg cgctccatga tcaccgcgat ggggaattct ttcatcgtgc
     8521 tgcacccgga aaggaaggcc tatgtctttc atagcatacg tgcccgcccg gcagcgcgcg
     8581 accgtggaaa cccgcggcgg cgaccccggc gacaaaggcg ccgctttcgc gcctgccggc
     8641 gctcctgcat gaaccatcac gcggccccga
//
LOCUS       DAOTIN010000132         8657 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_9763_length_8657_cov_8.191351, whole genome shotgun sequence.
ACCESSION   DAOTIN010000132 DAOTIN010000000
VERSION     DAOTIN010000132.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 8657)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 8657)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8657
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_9763_length_8657_cov_8.191351"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..921)
                     /locus_tag="P5537_14495"
     CDS             complement(<1..921)
                     /locus_tag="P5537_14495"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79296.1"
                     /translation="MLTFVNPLEKVAAVRLLEFLAETKPWYRSLWGIGVVLAMEELHE
                     ACAAMRQGHLSEAAIKRMASSLQKRVGVHPGFTDAEKQFLRQQLQQVPRADGVAHFGI
                     RELSARVSSDYLTRWGRAVTGGRFTVEHFARSVAAYLLDAGFAGQYLHNFIKARLDAP
                     ELISLSQLCDALQAEMLASPRREFEVLLAFTTTPARLNGIPSSWLQGAAIIAWLKEHG
                     FDTAGVRSPVAMVLKVQARDAFGAAKAARNEVDRYAARALIATGEPLNCVPMLWVKGS
                     TAPAPLKEASRGVGVKELFREDRVFSTGASQ"
     gene            complement(1611..2198)
                     /locus_tag="P5537_14500"
     CDS             complement(1611..2198)
                     /locus_tag="P5537_14500"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79297.1"
                     /translation="MDQDTMPCESCGQLTPHYDIVSYRGAEGSCRPFCTRCFNADVAR
                     LGGLAHFEDIPLEPIDLTDSVGETHRFYFRTRLHGSIVALDAFELRDGRPSGYQCQVI
                     GNPEQELLALLAKLIERLRRLLSTRHLATEGEKTEIAEQTVRGRIDWDESAVERTPLL
                     VIDGREVSWSDFGRMLSAFEGWQFKLEIVDRSDEI"
     gene            complement(2525..4351)
                     /gene="glmS"
                     /locus_tag="P5537_14505"
     CDS             complement(2525..4351)
                     /gene="glmS"
                     /locus_tag="P5537_14505"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:0006040 - amino sugar metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HRV79298.1"
                     /translation="MCGIVTAIATNNVVPVLLEGLRKLEYRGYDSAGLAVLAGELTRL
                     RSCGRVAELAALADARQLSAHIGIAHTRWATHGVPSERNAHPHISGGLAVVHNGIIEN
                     FEAIRADLQGKGYVFESETDTEAIAHLVHYKLQGNIDLFEAVRQATVDLVGAYAIGVV
                     AEADPFRVIVARRGSPLLLGIGEDGMYAASDTAALLQVTRKIVYLEDGDLAELRRDSY
                     IVIRSDGSPVERDVHISSLSADAVELGKYRHYMQKEIFEQPQALAQTLELIAGGAGIT
                     PQHFGARAAEVFDGVRRVLVLACGTSYHAGLVARYWIESIAKLPVTVEIASEYRYRES
                     VPDPDTLVVVISQSGETADTLAALKHAKALGMQRTLAICNVPESAIVRETALRFITRA
                     GPEIGVASTKAFTTQLAAFALLTLALAKINGRLSAEDEERRLAALRHLPVAVQKVLEL
                     EPEIEQWAQRFAGKEHALFLGRGSHWPIAMEGALKLKEISYIHAEAYAAGELKHGPLA
                     LVDKDMPVIAVSPADELLEKLKSNLQEVRARGGELYVFADAGSEIPESEGVHILHMPE
                     HYGMLSPVLHVIPLQLLSYHAALVKGTDVDKPRNLAKSVTVE"
     gene            complement(4425..5786)
                     /gene="glmU"
                     /locus_tag="P5537_14510"
     CDS             complement(4425..5786)
                     /gene="glmU"
                     /locus_tag="P5537_14510"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HRV79299.1"
                     /translation="MQVVVLAAGQGKRMRSVLPKVLQPIAGKPMLAHVLDAARTLDAQ
                     RICVVYGHGGEVVRERLDAADLAWARQQPQLGTGHAVQQALPHLDDDHVALVLYGDVP
                     LIGVPTLRRLVAAAGDARLALLTVEMDNPTGYGRILRDAAGKVVRIVEEKDASDEERK
                     VREVNTGILVAPVRHLRAWLGRIGNDNAQGEYYLTDIIGLAVADGVEVTTVQPDAFAE
                     TLGVNNKMQLAELERIHQGNIARRLMEEGVTLIDPARIDVRGSLTVGRDVEIDVNCIF
                     EGEVELGDGVRIGANCVVRNARIGAGTRLEPFSHVDSTTMGQACVIGPYARTRPGTVL
                     GADVHLGNFVEVKNSVIADHSKANHLAYVGDADVGSKVNIGAGTITCNYDGANKYRTI
                     IEDEVFIGSDTQLVAPVRVGRGATLGAGTTLTKDAPAGQLTVSRTKQISLDHWKRPVK
                     QPR"
     gene            6064..7470
                     /locus_tag="P5537_14515"
     CDS             6064..7470
                     /locus_tag="P5537_14515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HRV79300.1"
                     /translation="MKAPAAQPMIQNRTFDEIQVGDFAQLVRTLRPEDIHLFAAMSGD
                     VNPTHVDLEYARSSQFREVVGHSMWGSTLISTVLGTEFPGPGTVYVSQGLNFWRPITI
                     GDTLTITVTCKEKFEHNHHVILDCLAVNQDGLKVIDGIAEVMAPTEKIARPRVVLPEV
                     TISDRELRYRHLLSVSSGLSPIPIAVVHPCDRESLLGPVQAARAGLVDPILVGPEARI
                     RAVAEENEIDVKGFRIVDTEHSHASAEVAVAMCRDGGAEALMKGSLHTDEMMSQVIKH
                     LRTGRRISHVFLADVPTYPHPLMITDAAIMIEPTLEDKVDIIQNAIELAHILGLPEPK
                     VAILSAVETVTSKIRSTIEAAALCKMADRGQIKGGLLDGPLAFDNAVSLVAAKTKGIK
                     SVVAGNADILVVPDLESGNMVAKQLEYLANALMAGVVLGARVPIVLTSRADTAETRTA
                     SCAVVQLMAHRKREALKA"
     gene            7467..8651
                     /locus_tag="P5537_14520"
     CDS             7467..8651
                     /locus_tag="P5537_14520"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004337066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008776 - acetate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006083 - acetate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006113 - fermentation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HRV79301.1"
                     /translation="MKAVLVLNAGSSSLKFALYPVNGDVAEAPAVSGQVEGIGATPEI
                     TLKTANGARIHEAVPTGGSQGEQHRDALNHVFALLNRHNPALDIVAAGHRIVHGGEHY
                     SAPTRLDESVLRTLDTFVPLAPLHQPHNLRAVRAVAGLMPQVPQVGCFDTAFHRTQPA
                     VAQAFALPRRLSAEGIKRYGFHGLSYDYVARQLPEIIGERARGAVVIAHLGNGASMCA
                     LRDGRSVASTMGFTAVEGLMMGTRTGSLDPGVMLYLMEQKGMDAKALTSLLYKESGLL
                     GVSGISQDMRTLLASDAPEAREAVELFCYRIARELGSLAAAAGGLDALVFTGGIGEHA
                     APVREKVATMAAWMGIEIDPAANADHARRIDTAASRVAVAVVPTNEERMIARYTAETL
                     GL"
BASE COUNT         1486 a         2829 c         2883 g         1459 t
ORIGIN      
        1 ctggctcgca ccagtggaaa aaacgcgatc ctcgcgaaag agttccttca cccctacgcc
       61 gcgggaggct tcttttaagg gcgcaggcgc ggtgctgcct ttgacccaga gcatcggaac
      121 gcaattcagt ggttcgccgg tggcgatcaa agcccgagca gcgtagcggt caacctcatt
      181 tcgtgccgcc ttcgccgcac caaaagcatc tctggcttgc accttgagta ccatcgccac
      241 aggggagcgc acccccgccg tgtcgaaacc gtgctctttc aaccaagcaa tgatggccgc
      301 accctgcaac catgaagagg gtatgccatt gagccgtgca ggagtggtag tgaacgccag
      361 caagacctca aactcccgtc gagggcttgc taacatctcc gcctgtagcg catcgcaaag
      421 ctgcgacagg gagatcaatt ccggcgcgtc gagccgagcc tttatgaagt tgtgtaggta
      481 ttgaccggcg aaccccgcat cgagcaggta agcagcaaca ctgcgagcga agtgctcgac
      541 agtgaacctg ccgccagtga cggcccttcc ccatcgtgtc agatagtccg acgagacgcg
      601 agctgagagc tcgcgaatcc cgaaatgggc caccccgtcg gctctgggca cctgctgcag
      661 ctgctgacga aggaactgct tctcggcatc agtaaagcca ggatgcaccc cgacccgctt
      721 ctggagagag gaggccattc gtttgatcgc agcttcgctc aaatgccctt gccgcatggc
      781 cgcacaggct tcatgcagtt cctccatcgc caacacaacg ccaatgcccc acaaggaccg
      841 ataccaaggc ttcgtctccg ccaggaactc taggagcctt acggcggcaa ccttctcgag
      901 tggattgaca aatgtgagca tggggcttat tgtgcctcat ctgccaacaa agcgttggct
      961 caccgtctag gcggggcgcg acccaagcgg aagcggcagt tcaactgctt aatccaaccg
     1021 gctcaagccc ccatttctta aaggccctgc gttgcagggc ctttttcttt gcgctgcgca
     1081 aaggagcccc ggcgcaatgg ctcgcaggcg caagcaattt cgccgaacag catcgcaccg
     1141 ggcctccgtc tgctttcagt ctgatccggg cactcgttca accctcatca ggtgaccggt
     1201 cctggccgag tgtgtgaggt cgggctgcgt gtcccagagc tgtcgttggc gatcaggcgg
     1261 aggtcgccct gggcgaccgt tcaggccgac gacttgccgg tgagcagtcg ccacgaacgg
     1321 ccggtctacc ctgtcaccag ccatagatgc cgggatgccg tgcaggagcc tctctgggtc
     1381 gttagagtga atgggaattt cagcaaccgg ccattcttat cgcatatagc cgagcggaat
     1441 cgagcgactt cattggccga cctgctgtgt gacggtgatt ttcaagttgt ttgccagttg
     1501 catagcgctc agccgccttc aagctggttc caaaagtcga tcccgtctga caaaacagta
     1561 ctcaactgcc gccctctgaa tgacgaagat gcaaagttta tgagcaccac ctagatctca
     1621 tcagaacgat caacgatctc aagcttgaac tgccagccct cgaacgccga cagcatacgc
     1681 ccgaagtcac tccatgagac ttcacggcca tcaatcacga gcagaggggt ccgctccacc
     1741 gcagactcat cccaatcgat acgcccccgc accgtctgct cagcgatctc cgttttctcg
     1801 ccttcagtcg ccagatgcct ggtcgagagc aaacggcgaa gtcgttcgat cagcttcgca
     1861 agcaatgcaa gtagctcttg ctcaggattc ccgatgacct ggcactgata gccagacggg
     1921 cgaccatctc gaagttcaaa ggcatccaga gcaacgatgc tcccatgaag acgcgttcgg
     1981 aagtagaaac gatgcgtctc ccctacgctg tccgtgaggt cgatcggttc gagcgggata
     2041 tcttcaaagt gcgcaagacc ccctagccgg gcaacgtccg cattgaagca tcgagtacaa
     2101 aacgggcggc agcttccttc ggcaccgcga taactgacga tgtcgtagtg cggcgtaagc
     2161 tggccacagc tctcgcatgg catcgtgtct tggtccatca cgccccctcg atgtgccttc
     2221 atttttgaag cttgctccgc cggccagttg ccggcgatac cctggctgat cgccaggagc
     2281 cgtggcgtca gagcacaccc gaaaaaaacg cccgagggac tccccgggcg ttttcgactt
     2341 tattgacctg ttctcgactt tattgccacg ttgtcgactt tatttgcgcg gaacagcggc
     2401 gccggcgcga gcgccatcac tgcggcgatc tgctcagggg tgacgagttg cacggcggcg
     2461 gctccggtat cacatgacga cctgaatatg gatcatgtga taccggatat caagtactac
     2521 gtcttcactc gaccgtgacc gacttcgcga ggttgcgtgg cttatccaca tccgtcccct
     2581 tcaccagcgc cgcgtggtac gacagcagct gcagcgggat cacgtgcagc accggcgaca
     2641 gcatgccgta gtgctcgggc atgtgcagga tgtgcacgcc ttccgattcc ggaatctcgc
     2701 tgcccgcgtc ggcgaacacg tagagctcgc cgccgcgcgc gcggacttcc tgcaggttgg
     2761 acttgagctt ttcgagcagc tcgtcggcgg gggacacggc gatcaccggc atgtccttgt
     2821 ccaccagggc gagcgggccg tgcttgagct cgccggcggc gtaggcctcg gcgtggatgt
     2881 aggagatctc cttgagcttg agcgcgccct ccatggcgat cggccagtgg ctgccgcggc
     2941 cgaggaagag cgcgtgctcc ttgccggcga agcgctgcgc ccactgctcg atctcgggtt
     3001 cgagctcgag caccttctgc accgcgaccg gcaggtggcg cagcgcggcg aggcggcgct
     3061 cctcgtcctc ggcggacagc cgcccgttga tcttggcgag cgcgagcgtg agcagcgcga
     3121 aggcggcgag ctgggtggtg aaggccttgg tggaggcgac gccgatctcg gggccggcac
     3181 gggtgatgaa gcgcagcgcg gtctcgcgca cgatggccga ctcgggcacg ttgcagatcg
     3241 ccagcgtgcg ctgcatgccg agcgccttgg cgtgcttgag cgcggccagg gtgtcggcgg
     3301 tctcgcccga ctgcgagatg accacgacca gggtgtcggg gtcgggcacg gattcgcgat
     3361 agcggtattc gctggcgatc tcgacggtga ccggcagctt ggcgatggat tcgatccagt
     3421 agcgcgcgac caggccggcg tggtagctgg tgccgcaggc gagcacgagc acgcggcgca
     3481 cgccgtcgaa gacctcggcc gcacgcgcgc cgaagtgctg cggggtgatg ccggcgccgc
     3541 cggcgatcag ctccagggtc tgggccagcg cctgcggctg ctcgaagatc tccttctgca
     3601 tgtagtggcg gtacttgccg agctccacgg cgtcggccga caggctggag atgtgcacat
     3661 cgcgctcgac cgggctgccg tcggagcgga tcacgatgta gctgtcgcgg cgcagttcgg
     3721 cgaggtcgcc gtcttcgaga tagacgatct tgcgggtgac ctgcagcagc gcggcggtgt
     3781 cggaggcggc gtacatcccg tcctcgccga tgccaagcag cagcggcgag ccgcggcggg
     3841 cgacgatgac gcggaagggg tcggcctcgg cgaccacgcc gatggcgtag gcgccgacga
     3901 gatcgacggt ggcctggcgc acggcctcga agaggtcgat gttgccctgc agcttgtagt
     3961 gcaccaggtg ggcgatagcc tcggtgtcgg tctcggactc gaagacgtag cccttgccct
     4021 gcaggtcggc cctgatggcc tcgaagttct cgatgatgcc gttatgcacc acggcgaggc
     4081 cgccggagat gtgcgggtgg gcgttgcgct cggagggcac gccgtgggtg gcccagcgcg
     4141 tgtgggcgat gccgatgtgg gcggagagct ggcgcgcatc ggccagcgca gcgagctcgg
     4201 ccacgcggcc gcaggagcgc aggcgggtga gctcgccggc gagcacggcg aggccggcgg
     4261 agtcgtagcc acggtattcg agcttgcgca ggccctcgag caggaccggg acgacgttgt
     4321 tggttgcgat tgcggtgacg atgccacaca tggcggggct tccttgtcgg tctttggatt
     4381 cggtgcggag ggcgggtcgg gcggaacgcg ctggcggcag cgcctcagcg cggctgcttg
     4441 accgggcgct tccagtggtc gaggctgatc tgcttggtgc gcgacaccgt gagctggccg
     4501 gcgggcgcgt ccttggtgag cgtggtgccg gcgcccaggg tggcgccgcg gcccacgcgc
     4561 accggggcga cgagctgggt gtcggagccg atgaagacct cgtcctcgat gatggtgcgg
     4621 tacttgttgg cgccgtcgta gttgcaggtg atggtgccgg cgccgatatt gaccttgctg
     4681 ccgacgtcgg cgtcgcccac gtaggcgagg tggttggcct tggagtggtc ggcgatgacg
     4741 ctgttcttga cctcgacgaa gttgcccaga tgcacgtcgg cgccgagcac ggtgcccggg
     4801 cgggtgcggg cgtagggccc gatcacgcag gcctggccca tggtggtgct gtcgacgtgg
     4861 ctgaagggct cgagccgggt gccggcgccg atgcgggcgt tgcggacgac gcagttggcg
     4921 ccgatgcgca cgccgtcgcc cagctcgacc tcgccctcga agatgcagtt cacgtcgatc
     4981 tcgacgtcgc ggccgaccgt gaggctgccg cgaacgtcga tgcgggccgg gtcgatcagg
     5041 gtgacgccct cttccatcag gcggcgggcg atgttgccct ggtggatgcg ctcgagctcg
     5101 gcgagctgca tcttgttgtt gaccccgagc gtctcggcga aggcatcggg ctgcacggtg
     5161 gtgacctcga cgccgtcggc cacggccagg ccgatgatgt cggtgaggta gtactcgccc
     5221 tgggcgttgt cgttgccgat gcggccgagc caggcgcgca ggtggcggac cggggcgacc
     5281 aggatgccgg tgttcacctc gcggaccttg cgctcctcgt ccgaggcgtc cttctcctcg
     5341 acgatgcgca ccaccttgcc ggcggcgtca cgcaggatgc ggccgtagcc ggtcgggttg
     5401 tccatctcga cggtgagcag cgcgaggcgc gcgtcgccgg cggcggcgac caggcggcgc
     5461 agcgtgggca cgccgatcag cgggacgtcg ccgtacagca ccagcgccac gtggtcgtcg
     5521 tcgaggtggg gcagcgcctg ctgcaccgcg tgaccagtgc cgagctgcgg ctgctgccgc
     5581 gcccacgcca ggtcggcggc atcgaggcgc tcgcgcacca cctccccacc gtggccatac
     5641 accacgcaga tgcgctgcgc gtcgagggtg cgcgcggcgt cgagcacgtg ggccagcatc
     5701 ggcttgccgg cgatgggttg gaggaccttg ggcagcaccg agcgcatgcg cttgccctgg
     5761 ccggcagcga gaacgacgac ttgcatggtt gattccgtgg cgaaatgggg aggttcgaca
     5821 ggttacgggc gcaggatcga gctcgtccgc gcccgcggat cggaaaaacg cgcggagtct
     5881 agcacgcgac ccgcacgacc gatcgtgagc aaacgcatgg tgagggcatg aaaaaacccg
     5941 ctcagcgcaa ggaaacgcgc gtctgattga cgcattgcac aattcgatcg ttttagcgca
     6001 tgtttcagtc acatacaagg tctagaatcg cgcgttgcaa tgcacccaag aacgagagtt
     6061 gccatgaaag cccctgccgc acaaccgatg atccagaacc gcaccttcga cgagatccag
     6121 gtgggcgact tcgcccagct cgtccgcacg ctgcgcccgg aggacatcca cctcttcgcc
     6181 gcgatgtccg gcgacgtcaa cccgacccac gtcgatctcg agtacgcgcg ttcaagccag
     6241 ttccgagagg tcgtcggcca cagcatgtgg ggcagcacgc tgatctccac cgtgctcggc
     6301 accgaattcc ccggccccgg cacggtgtac gtgtcgcagg ggctcaactt ctggcgcccg
     6361 atcacgatcg gcgacacgct cacgatcacg gtcacctgca aggaaaagtt cgagcacaac
     6421 caccacgtga tcctcgactg cctggcggtg aaccaggacg gcctcaaggt aatcgacggc
     6481 atcgccgagg tgatggcgcc gaccgagaag atcgcccgtc cgcgcgtcgt gctgcccgag
     6541 gtcaccatct ccgaccgcga gctgcgctac cgccacctgc tgtcggtgtc gtccggcctg
     6601 tcgccgatcc cgatcgcggt ggtgcatccc tgcgaccgcg aatccctcct cggtccggtc
     6661 caggcggcgc gcgccggact ggtcgatccg atcctggtcg gtcccgaggc gcgcatccgc
     6721 gccgtcgctg aagagaacga gatcgacgtc aagggcttcc gcatcgtcga caccgagcac
     6781 agccacgcct cggcagaggt cgcggtggcg atgtgccgcg acggcggcgc cgaagcgctg
     6841 atgaagggct cgctgcacac cgacgagatg atgagccagg tcatcaagca cctgcgcacc
     6901 ggccgccgca tcagccacgt cttcctggcc gacgtgccga cctacccgca cccgctgatg
     6961 atcaccgacg cggcgatcat gatcgagccg acgctcgagg ataaggtcga catcatccag
     7021 aacgcgatcg agctcgccca catcctcggc ctgcccgagc ccaaggtggc gatcctgtcg
     7081 gcagtcgaga ccgtgacctc gaagatccgc tcgacgatcg aagccgccgc gctgtgcaag
     7141 atggccgacc gcggccagat caagggtggc ctgctcgacg gcccgctcgc cttcgacaat
     7201 gcggtgtcgc tggtcgccgc gaagaccaag ggcatcaagt ccgtggtcgc cggcaacgcc
     7261 gacatcctcg tggtgcccga cctcgagtcc ggcaacatgg tcgccaagca gctcgagtac
     7321 ctcgccaacg cgctgatggc cggcgtggtg ctgggcgcgc gcgtgccgat cgtgctcacc
     7381 agccgcgccg acacagccga gacgcgcacc gcgtcgtgcg ccgtggtgca gctgatggcc
     7441 cacaggaagc gtgaggcgct gaaagcatga aggccgtcct cgttctcaac gccggctcgt
     7501 cgagcctgaa gttcgcgctc tatccggtca acggcgatgt ggccgaggcg ccggcggtgt
     7561 ccggccaggt cgaaggcatc ggcgccacgc ccgagatcac gctcaagacc gccaacggtg
     7621 cgcgcatcca tgaagcggtg cccaccggcg gcagccaggg cgaacagcat cgtgacgcgc
     7681 tcaaccatgt gttcgcgctg ctgaaccgtc acaacccggc gctcgacatc gtcgccgccg
     7741 gccaccgcat cgtgcatggc ggcgagcact acagcgcgcc cacccggctc gacgagtcgg
     7801 tgctgcgtac gctcgacacc ttcgtgccgc tcgccccgct gcaccagccg cacaacctgc
     7861 gcgcggtgcg cgcggtcgcg gggctgatgc cgcaggtgcc gcaggtcggc tgcttcgaca
     7921 ccgccttcca ccgcacccag ccggcggtcg cgcaggcctt cgcgttgccg cgcaggctgt
     7981 cggccgaggg catcaagcgc tatggcttcc acggcctgtc ctacgactac gtggcgcgcc
     8041 agttgccgga aatcatcggc gagcgcgcca ggggcgcggt ggtgatcgcc cacctgggca
     8101 acggcgcctc gatgtgcgcg ctgcgcgacg gtcgcagtgt cgcgtcgacg atgggcttca
     8161 ccgcggtcga gggcctgatg atgggcaccc gcaccggcag cctcgacccc ggcgtgatgc
     8221 tctacctgat ggagcagaag ggcatggacg cgaaggcgct caccagcctg ctctacaagg
     8281 aatcaggcct gctcggcgtg tcgggcatca gccaggacat gcgcaccctg ctcgcctccg
     8341 acgcccccga ggccagggag gcggtcgagc tgttctgcta ccgcatcgcg cgcgagctcg
     8401 gctcgctggc tgcggccgcg ggcgggctgg atgcgctggt gttcaccggc ggcatcggcg
     8461 agcacgccgc gccggtgcgc gagaaggtgg ccacgatggc ggcgtggatg ggcatcgaga
     8521 tcgaccccgc cgccaacgcc gaccacgccc gccgcatcga caccgcagcc agccgtgtcg
     8581 cggtcgccgt ggtgccgacc aacgaagaac gcatgatcgc gcgctacacg gccgagacgc
     8641 tagggctgta agccgca
//
LOCUS       DAOTIN010000133         8596 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_9855_length_8596_cov_8.467978, whole genome shotgun sequence.
ACCESSION   DAOTIN010000133 DAOTIN010000000
VERSION     DAOTIN010000133.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 8596)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 8596)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8596
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_9855_length_8596_cov_8.467978"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            2..589
                     /locus_tag="P5537_14525"
     CDS             2..589
                     /locus_tag="P5537_14525"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HRV79302.1"
                     /translation="MLLMIDNYDSFTYNLVQYFGELGAKVKVYRNDEITLEQIARLAP
                     AHLVISPGPCSPAQAGISVAAIKAFAGKLPILGVCLGHQSIGEAFGGRIVHAKQLMHG
                     KTSPVHHLDAGVFRGLPNPLTCTRYHSLAIERPSLPDCLEVTAWTEDGEIMGVRHRTL
                     DVEGVQFHPESILTECGHALLKNFLDRRAAAPAAA"
     gene            611..1654
                     /gene="trpD"
                     /locus_tag="P5537_14530"
     CDS             611..1654
                     /gene="trpD"
                     /locus_tag="P5537_14530"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HRV79303.1"
                     /translation="MTTITPQQALQRTIEHREIFFDEMLSLMRQIMAGEISPVMTAAI
                     LTGLRVKKETISEITAAATVMREMSTKVVVEPPHDHFLDVVGTGGDGANTFNISTTTI
                     FVAAAAGARVAKHGGRGVSSKSGAADVIEALGVNLDLTPQQVAECIEATGIGFMYAPA
                     HHSAMKNVAPVRREMGVRTIFNILGPLTNPASAPNTLMGVFHPDLVGIQARVMQRLGA
                     NHVMVVHGLDGMDEVSLGGATLVGELKNNEVSEYEIHPEDFGLAMAGSRQLRVEDATE
                     SREMLLGVLDNRPGAAREIVIFNAGVALYTANLVDTIGAGILRAREIIESGAARAKLD
                     EFVRFTQQFRSGR"
     gene            1651..2451
                     /gene="trpC"
                     /locus_tag="P5537_14535"
     CDS             1651..2451
                     /gene="trpC"
                     /locus_tag="P5537_14535"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004425 - indole-3-glycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HRV79304.1"
                     /translation="MSDILQKICAVKVEEVAAAAAARPQCLVREDAAAQPPARDFVGA
                     IRARHAAHRPAVIAEIKKASPSKGVIRADFHPAEIAADYERAGAACLSVLTDRGFFQG
                     APEYLQAARAACHLPVLRKDFLVDPYQVFEARAMGADAILLIAACLDLAQMRDMEQLA
                     TELGMAVLVEVHDAAELEQALQLDTPLIGINNRNLRSFEVSLQTTLDLLPRIASGAAG
                     RIVVTESGILKPEDVALMQANAVHTFLVGEAFMRAPHPGAELQTLFGR"
     gene            2461..6918
                     /locus_tag="P5537_14540"
     CDS             2461..6918
                     /locus_tag="P5537_14540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translocation/assembly module TamB
                     domain-containing protein"
                     /protein_id="HRV79305.1"
                     /translation="MSAHEHDSTPDSVAPPRRRRLARVLGWGVALPLALLLGGGAWLA
                     GTQSGLDAALGLAARATSGALQVEGARGRLLGRLDVDRLAWRGPGLELEVRALALAWS
                     PSALLQRRVDIDHLTAARVLLAQAVAEDEPAAAPLVAPSSLELPVAIALRRLAVGAFL
                     MRELPASGEATAPLADAASSSASARAVSPVAAERDPGGADGAVPVPAAAAAPARGEVA
                     AAAAAGEAAQALDRAADVASDPKLAAEAATEVAAEQGLVFSRLEAALSSDGRHHRLEA
                     LAVELPQGRAHAALALDGVAPFALAGEVGFDGVVETHAAAVQATLADSLLEPRLQARA
                     TLGAAHAEVDARVDSFAADPLRQLRLEAGGIDPAAFAAGAPTGEFAVQAELAAPAAGE
                     GLLAGPIRITNARAAAVDAGGIPLDAVVAQLDWKRAELALDALEFRLAGGGTIAGRVA
                     WRPPAVPEVGEGGTPPASAATDGEPGTAVDSSAPAATAPQRHNAAATAPAAPAADGGF
                     GQLAAVLELAGIDTQALDGRLPRQIVAGRVDAEADAQRQTARLALAVGEARIDADASL
                     IAAPAAPVAVAGAGGEQAVPAPDGAAVTPPVAAPATHAPAPPVRSFTLSARLRGIDPR
                     ALQAGLPSARLNLDLDARGDLPAEGLPQAVALDFTIPDSRLDGRPLRGQGRLRLEGLR
                     LPEAKIDLDVAGNTLAAEGAFGAPGDSLALRLDAPALAAIGFGLGGRAGAEGRIGGTL
                     EAPNGRLDLFGENLALPGEVRLAGVNGRVRLDSGIDGPFEIALGLSRLGSRARAADGA
                     VQPDWLASARVEASGTRARHRLDADLATPKLEGVADTLRLALEGGLAAGGTPRWSGRL
                     AALEAGGRFPARLQAPATLELGADRVRLGRVEIEAGDKGRIRLLETVWSPAQSVLRGD
                     LAGLVVETEPPRRDGRPRRNADPLRLGARWDLSVGRTLEGEARVFREAGDISVEGELR
                     TRLGLEKLEAALNARGDRIELAVDVQGKELGSVQGEAGLRARRGADGLWSVPPATAIR
                     GAARLDMPSLAWLGRLSQESVELAGRLRGDFTVGGTIEAPRASGRIEGRELGFTLVDQ
                     GLILAGGELDLDFDQQRVRLERLEFVSENRVRPRESRIPFERLTATPGRFTARGELAL
                     DSGAGDFRFDADRLPLLQRDDRWMLLSGGGTARSTLESLSLDAEFRADAGYIEFAEAL
                     PPSLSDDVVVLGRNPAPAQEGGGFAVNADVRVGLGDALYLSALGLETRLAGGLRIRLQ
                     PGRPLSAVGTIETVGGGYRGYGQNLTLERGLINFQGPLDAPGLNIVALRKGLEVEAGV
                     AITGSAKRPQIKLVSDPEVPDPAKLSWIVLGRAPDAGSGADLGLLLPAAAALLGGPAG
                     GMTEELSRSLGLDSFSIGQGELNSTTRARSSRVLGSGQTVSGGPSVSSQVLSLGKRLG
                     PDLFLNFEQSLGGAATLVKLTYQISRRLSVIARGGTDTALDVQYGFSFR"
     gene            6997..7566
                     /gene="msrA"
                     /locus_tag="P5537_14545"
     CDS             6997..7566
                     /gene="msrA"
                     /locus_tag="P5537_14545"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004386185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HRV79306.1"
                     /translation="MTENKNEPVRETAILGGGCFWCLEAVFDLVAGVDEVVPGYCGGH
                     VDLPGYRDVCSGGTGHAEVVKIVFDPEKVSYRELLDVFFTIHDPTTVDRQGNDVGPQY
                     RSVIFATTEAQLHTALATIEELGERRVFPKAIVTRVERAPRFWPAEPEHHDYYVNNSD
                     QPYCQYVVAPKITKFRSHFDLRRWPEGSR"
     gene            7600..7944
                     /locus_tag="P5537_14550"
     CDS             7600..7944
                     /locus_tag="P5537_14550"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HRV79307.1"
                     /translation="MTQTTTASGLVIDELELGSGDTAEKGRMVSVHYTGWLTDGRKFD
                     SSKDRNDPFVFPLGAGHVIRGWDEGVQGMQVGGKRKLTIPPELGYGARGAGGVIPPNA
                     TLVFEVELLKVL"
     gene            8088..8546
                     /locus_tag="P5537_14555"
     CDS             8088..8546
                     /locus_tag="P5537_14555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004386182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HRV79308.1"
                     /translation="MKLDPAQRHILTLLQKDSTLSTQVLADKVGMSPTPCWRRVRDME
                     EAGVIRGYVALVDRHKVGLGTCVWVRVKLKQHSADVLDRFERVVKACEQVVECYELLG
                     ETDCLLKLYLPNLEALSVFMHEFLLKIPEIDVTHSAVALREIKNETALPL"
BASE COUNT         1176 a         3256 c         3003 g         1161 t
ORIGIN      
        1 catgctgctg atgatcgaca actacgacag cttcacctac aacctcgtgc agtacttcgg
       61 cgaactcggc gccaaggtca aggtgtaccg caacgacgag atcaccctcg agcagatcgc
      121 gcgcctcgcg cccgcgcacc tcgtcatttc gcccgggccg tgctccccgg cccaggccgg
      181 catctcggtg gcggcgatca aggccttcgc cggcaagctg cccatcctcg gcgtctgcct
      241 cggccaccag agcatcggcg aggccttcgg cgggcgcatc gtgcacgcca agcagctgat
      301 gcacggcaag acctcgccgg tgcatcacct cgatgcgggc gtcttccgcg gcctgcccaa
      361 cccgctcacc tgcacgcgct accattcgct ggcgatcgaa cgcccgagcc tgcccgactg
      421 tctggaagtg acggcctgga ccgaggacgg cgagatcatg ggcgtgcgcc acaggacgct
      481 cgacgtcgag ggtgtgcagt tccaccccga gtccatcctc accgagtgcg gccacgcgct
      541 gctgaagaat ttcctcgatc gccgcgccgc cgcgccggcg gccgcctgac atgaacgctg
      601 cgagagtccc atgaccacga tcacccccca gcaagccctg caacgcacga tcgagcatcg
      661 cgagatcttc ttcgacgaga tgctgtcgct gatgcgccag atcatggccg gcgagatctc
      721 gccggtgatg accgccgcca tcctcaccgg cctgcgcgtc aagaaggaga ccatcagcga
      781 gatcaccgcc gccgccacgg tgatgcgcga gatgtcgacc aaggtcgtgg tcgagccgcc
      841 gcacgaccac ttcctcgacg tcgtcggcac cggcggcgac ggcgccaaca ccttcaacat
      901 ctccaccacc acgatcttcg tcgccgccgc cgccggcgcg cgcgtggcca agcacggcgg
      961 gcgcggggtg tcgtccaagt cgggcgcggc cgacgtgatc gaggcgctcg gtgtcaatct
     1021 ggatctcacg ccgcagcagg tcgccgagtg catcgaggcc accggcatcg gcttcatgta
     1081 cgcccccgcc caccacagcg cgatgaagaa cgtcgccccg gtgcggcgcg agatgggcgt
     1141 gcgcaccatc ttcaacatcc tcggccccct caccaacccg gcgagcgcgc ccaacaccct
     1201 gatgggcgtg ttccaccccg acctggtcgg catccaggcg cgcgtgatgc agcgcctcgg
     1261 cgccaaccac gtgatggtgg tgcacggcct ggacggcatg gacgaggtca gcctgggcgg
     1321 cgccaccctg gtcggcgagc tcaagaacaa cgaggtctcc gagtacgaga tccaccccga
     1381 ggacttcggc ctcgccatgg cgggcagccg ccagctgcgc gtcgaggacg ccaccgagtc
     1441 gcgcgagatg ctgctcggcg tgctcgacaa ccgccccggc gcggcgcgcg agatcgtgat
     1501 cttcaacgcc ggcgtggcgc tgtacaccgc caacctggtc gacaccatcg gcgccggcat
     1561 cctgcgcgcg cgcgagatca tcgagagcgg cgccgcgcgc gccaagctcg acgagttcgt
     1621 gcgcttcacc cagcagttcc ggagcggccg atgagcgaca tcctgcagaa gatctgcgcg
     1681 gtcaaggtcg aggaggtcgc cgcggccgcc gccgcgcggc cgcagtgcct ggtgcgcgag
     1741 gacgccgctg cgcagccgcc tgcgcgcgac ttcgtcggtg cgatccgcgc cagacacgcc
     1801 gcccaccgcc ccgcggtgat cgccgagatc aagaaggcca gcccctccaa gggcgtgatc
     1861 cgggccgact tccaccccgc cgagatcgct gccgactacg agcgcgccgg cgccgcctgc
     1921 ctgtcggtgc tcaccgaccg cggcttcttc cagggcgcgc ccgaatacct ccaggcagcg
     1981 cgcgccgcct gccacctgcc ggtgctgcgc aaggacttcc tcgtcgatcc ctatcaggtc
     2041 ttcgaggcgc gcgcgatggg tgccgacgcc atcctgctga tcgccgcctg cctcgacctg
     2101 gcgcagatgc gcgacatgga gcagctcgcg accgagctcg gcatggccgt gctggtcgag
     2161 gtgcatgacg ccgccgagct cgagcaggcg ctgcagctcg acacgccgct gatcggcatc
     2221 aacaaccgca acctgcgcag cttcgaggtc tcgctgcaga ccacgctcga cctgctgcca
     2281 cgcatcgcca gcggcgctgc gggccgcatc gtggtcaccg agtccggcat cctgaaaccg
     2341 gaggacgtcg ccctgatgca ggccaacgcg gtgcatacct tcctggttgg cgaggccttc
     2401 atgcgcgcgc cgcatccggg cgccgaactg cagacgctgt tcggccgctg aggcgcccgg
     2461 gtgagcgcgc acgagcacga ctccacgccc gactccgtcg cgccgccgcg caggcgccgg
     2521 ctggcgcgcg tgctcggctg gggcgtcgcg ttgccgctgg cgctgctgct cggcggcggc
     2581 gcctggctcg ccggcaccca gtccgggctc gacgccgcgc tcggcctcgc cgcgcgcgcc
     2641 acttcgggtg cgttgcaggt cgagggcgcg cgtggacggc tcctcggccg cctcgacgtt
     2701 gaccggctgg cctggcgcgg gccggggctg gagctcgagg tgcgcgcgct ggcgctcgcg
     2761 tggtcgccgt cggcgctgct gcagcgccgt gtcgacatcg accacctcac cgccgcgcgc
     2821 gtgctgctcg cccaggcggt ggccgaggac gaacccgccg ccgcgcccct ggtggcgcct
     2881 tcctcgctgg agctgccggt tgcgatcgcg ctgcgccggc tcgcggtggg cgccttcctg
     2941 atgcgcgagc tgcccgccag cggggaggcc acggcgccgc tcgccgatgc tgcgtcgtcg
     3001 agcgcttccg ctcgggcggt ctccccggtc gctgctgagc gtgaccccgg aggtgccgac
     3061 ggcgccgtgc ctgtccccgc ggccgcggcg gcgcccgctc ggggcgaggt cgccgccgcg
     3121 gccgcggccg gtgaggccgc gcaggcgctc gatcgcgccg cggacgttgc cagcgacccc
     3181 aagctcgccg ccgaggcagc gaccgaggtg gccgccgagc agggcctggt gttctcgcgc
     3241 ctcgaagccg cgctctccag cgacggccgc catcaccgcc tcgaagccct cgcggtcgag
     3301 ctgccgcagg gccgcgctca tgcggcgctc gcgctcgacg gcgtggcacc cttcgcgctc
     3361 gcaggtgagg tgggcttcga cggtgtcgtc gagacccacg ccgccgcggt gcaggcgacg
     3421 ctcgccgaca gcctgctcga gccgcgtctg caggccaggg ccacgctggg cgccgcgcac
     3481 gccgaagtcg atgcgcgcgt cgacagcttc gccgccgatc ccttgcggca gctgcgcctc
     3541 gaggctggcg gcatcgatcc cgcagccttc gctgccggcg cgccgaccgg cgagttcgcc
     3601 gtacaggccg agctcgccgc tcccgccgcg ggcgagggcc tgctcgccgg cccgatccgt
     3661 atcaccaacg cccgtgctgc cgcggtggat gctggcggga tcccgctcga cgcagtggtg
     3721 gcgcagctcg actggaagcg cgccgagctc gccctcgacg ccctcgaatt ccgcctcgcc
     3781 ggtggcggca ccatcgccgg ccgcgtggcc tggcgtccgc cggcggtgcc cgaggtcggg
     3841 gagggcggga caccgccggc gtccgcggcg acggatggcg agcccgggac ggcggtggat
     3901 tcgtccgcgc cggctgccac ggcgccgcag cgtcacaacg cggccgcaac cgccccggcc
     3961 gcgccagcgg ccgacggagg attcggccag ctcgccgccg tgctcgaact cgccggcatc
     4021 gacacgcagg ccctcgacgg ccgcctgccg cgccagatcg ttgccggacg ggtggatgcc
     4081 gaggccgacg cgcagcgcca gacggcgcgg ctcgcgctcg cggtgggcga ggcccgcatc
     4141 gacgccgacg ccagcctcat cgccgcgccc gccgcgccag tggcggtggc gggtgcaggc
     4201 ggcgagcaag cggtgcccgc ccccgatggt gccgccgtca cgcccccggt tgccgcgccg
     4261 gcaacgcatg cgcccgcgcc accggtgcgc agcttcaccc tgtcggcgcg cctgcgcggt
     4321 atcgatccgc gcgcgctgca ggccgggctg ccgagcgcgc gcctcaacct cgacctcgac
     4381 gcgcgcggcg acctccccgc cgagggcctg ccgcaggcgg tcgcactcga cttcaccatc
     4441 cccgacagcc ggctcgacgg ccgcccgctc cgcggccagg gtcgcctgcg cctggaaggc
     4501 ctgcgcctgc cggaggcgaa gatcgacctc gatgtcgccg gcaacaccct ggccgccgag
     4561 ggggccttcg gcgcgcccgg cgacagtctg gcgctgcgcc tggacgcgcc cgcgctggcg
     4621 gcgatcggct tcgggctcgg cggccgcgcc ggcgccgagg gccgcatcgg cggcacgctc
     4681 gaggcgccca acggccgcct cgacctcttc ggcgagaacc tcgccctgcc cggcgaagtg
     4741 cgcctggccg gggtgaatgg tcgcgtccgc ctcgattccg gaatcgacgg ccccttcgag
     4801 atcgcgctcg gcctcagccg cctcggcagc cgcgcgcgcg ccgccgacgg cgcggtgcag
     4861 cccgactggc tggcgagtgc gcgtgtcgag gccagcggca cgcgcgctcg ccaccgcctc
     4921 gacgccgacc tcgccacgcc caagctcgag ggcgtcgcag acaccctgcg cctcgccctc
     4981 gaaggcggcc tggcggcggg cgggacgccg cgctggagcg gtcgcctcgc tgcgctcgaa
     5041 gcgggcgggc gctttccggc gcgcctgcag gcgccggcca cgctcgagct cggcgccgat
     5101 cgcgtgcgcc tcggccgcgt cgagatcgag gccggcgaca agggccgcat ccgcctgctc
     5161 gagaccgtct ggtcgccggc acagagcgtg ctgcgcggcg atctcgccgg gctggtggtc
     5221 gagaccgaac cgccgcgtcg tgacgggcgc ccgcgccgca acgccgaccc gctgcgcctg
     5281 ggcgcgcgct gggacctctc ggtcgggcgc accctcgaag gcgaggcgcg cgtgttccgc
     5341 gaggccggcg acatcagcgt ggaaggcgag ctgcgcaccc ggctcggcct ggagaagctc
     5401 gaggcggcgc tgaacgcgcg cggcgatcgc atcgagctcg ccgtcgacgt gcagggcaag
     5461 gagctcggca gcgtgcaggg cgaggccggg ctgcgcgcgc ggcgcggcgc cgacggcctg
     5521 tggagcgtgc cgccggcgac cgcgatccgc ggcgcggcgc gcctcgacat gccctcgctc
     5581 gcctggctcg ggcgcctctc gcaggagagc gtcgagctgg ccgggcgcct gcgcggcgac
     5641 ttcaccgtgg gcggcacgat cgaggcgccg cgcgcgagcg gccgcatcga gggacgcgag
     5701 ctcggcttta ccctggtcga ccagggcctg atcctcgccg gcggcgagct cgacctcgac
     5761 ttcgaccagc agcgcgtgcg cctggagcgg ctcgagttcg tgtccgagaa ccgcgtgcgc
     5821 ccgcgcgaga gccgcatccc cttcgagcgc ctcaccgcca cgcccgggcg cttcaccgcg
     5881 cgcggcgagc tcgcgctcga cagcggcgcg ggcgatttcc gcttcgacgc cgaccgcctg
     5941 ccgctgctgc agcgcgacga ccgctggatg ctgctctcgg gtggtggcac ggcgcgcagc
     6001 accttggagt cgctgtcgct ggacgcggag ttccgcgccg acgccggcta catcgagttc
     6061 gccgaggcgc tgccgcccag cctgtccgac gatgtcgtcg tgctcgggcg caaccccgca
     6121 ccggcgcagg aggggggcgg cttcgcggtc aatgcggacg tccgtgtcgg cctcggcgat
     6181 gccctctacc tgtcggcgct cggcctggag acacggctcg ccggcggcct gcgcatccgc
     6241 ctgcagcccg ggcggccgct gtcggcggtg ggcacgatcg agaccgtggg tggcggctac
     6301 cgcggctacg gccagaacct caccctggag cgcggcctga tcaacttcca gggcccgctc
     6361 gacgcacccg ggctcaacat cgtcgcgctg cgcaaggggc tcgaggtcga ggccggggtg
     6421 gcgatcaccg gcagcgccaa gcgcccgcag atcaagctgg tgtccgaccc cgaggtgccc
     6481 gaccccgcca agctgtcgtg gatcgtgctc gggcgcgcgc ccgacgccgg ctcgggcgcc
     6541 gacctcggcc tgctgctccc cgccgcggcg gcgctgctcg gcggcccggc cggcggcatg
     6601 accgaggagc tctcgcgcag cctcggctta gactccttct cgatcggcca gggcgagctc
     6661 aacagcacta cgcgcgcgcg cagcagccgg gtgctcggca gcgggcagac ggtctccggc
     6721 gggccctcgg tgtccagcca ggtgctgagc ctgggcaagc gcctcgggcc ggacctcttc
     6781 ctcaacttcg agcagagcct gggcggggcc gccaccctgg tcaagctgac ctaccagatc
     6841 tcgcgccggc tttccgtgat cgcccgcggc ggcaccgaca ccgcgctcga cgtccagtac
     6901 ggcttctcct tccgttgaga cacgtggcgg acggggaatg attccccgtc cgcgcggtct
     6961 ctccgatgcc atgaccaacc ccgatggagc gagcagatga cagagaacaa gaacgagccg
     7021 gtgcgcgaga ccgccatttt gggcggcggc tgcttttggt gcctggaggc ggtgttcgac
     7081 ctggtggccg gtgtggacga ggtcgtgccg ggctattgcg gcggccacgt cgatctgccc
     7141 ggctaccgcg acgtgtgttc cggcggcacc ggccatgccg aggtggtgaa gatcgtcttc
     7201 gatccggaga aggtgagcta ccgcgagctg ctcgacgtct tcttcaccat ccacgatccg
     7261 accacggtcg accgccaggg caacgacgtc ggcccgcaat accgctcggt gatcttcgcc
     7321 accaccgagg cgcagctgca caccgcgctc gccaccatcg aggagctcgg cgagcgccgt
     7381 gtcttcccga aggcgatcgt cacgcgcgtc gagcgtgcgc cgcgcttctg gccggccgag
     7441 ccggagcacc acgactacta tgtgaacaac agcgaccagc cgtactgcca gtacgtggtg
     7501 gcgcccaaga tcacgaaatt ccgcagccat ttcgacctgc gccgctggcc cgaaggcagc
     7561 aggtagaatg cgcgttttca ctcacggcag gagaacggca tgacccagac caccaccgcc
     7621 agcggactcg tcatcgatga actcgagctc ggcagcggcg acaccgccga gaagggccgc
     7681 atggtgtcgg tgcattacac cggctggctc accgacggac gcaagttcga ctcgagcaag
     7741 gatcgcaacg atcccttcgt cttcccgctc ggcgccggcc acgtgatccg cggctgggac
     7801 gagggcgtgc agggcatgca ggtcggcggc aagcgcaagc tcaccatccc gcccgagctc
     7861 ggctacggcg cgcgcggcgc cggcggcgtg atcccgccca acgccaccct ggtgttcgag
     7921 gtcgagctgc tgaaggtgct gtaaatcctc ttgtgggagc ggcttgccgg cgaacaacgg
     7981 cgctgcccga gcgccgcctg cgcgagcaag tccgctcccc cgggaatccg cgattggcgt
     8041 ccccgcgccc gcaccgacca gacgaccgcc gcacaaggcc acccctcatg aagctcgacc
     8101 cggcgcagcg acacatcctg acgctgctgc aaaaggactc caccctcagc acccaggtgc
     8161 tcgccgacaa ggtcggcatg tcgccgacgc cgtgctggcg gcgggtgcgt gacatggagg
     8221 aggcgggcgt gatccgcggc tacgttgcgc tggtcgaccg ccacaaggtc ggcttgggca
     8281 cctgcgtgtg ggtgcgcgtc aagctcaagc agcacagcgc cgacgtgctc gaccgcttcg
     8341 agcgcgtggt caaggcctgc gagcaggtgg tggagtgcta cgagctgctc ggcgagaccg
     8401 actgcctgct caagctctac ctgcccaacc tcgaggcctt gtcggtgttc atgcacgaat
     8461 tcctgctcaa gatcccagag atcgacgtca cccattccgc ggtggcgctg cgcgagatca
     8521 agaacgagac cgcgctgccc ttgtaggagc gccggcaggc gcgaacatgg cggcacgatt
     8581 cccgcccacg cgcctc
//
LOCUS       DAOTIN010000134         8588 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_9863_length_8588_cov_9.466776, whole genome shotgun sequence.
ACCESSION   DAOTIN010000134 DAOTIN010000000
VERSION     DAOTIN010000134.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 8588)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 8588)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8588
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_9863_length_8588_cov_9.466776"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1085)
                     /locus_tag="P5537_14560"
     CDS             complement(<1..1085)
                     /locus_tag="P5537_14560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enolase C-terminal domain-like protein"
                     /protein_id="HRV79309.1"
                     /translation="MTSPQSVSHAPVVTRMRVVPVAGQDSMLLNLSGAHGPYFTRNIL
                     ILEDSAGNTGLGEVPGGEKIRQTLEDARSLIVGQPTGNWNAILNAMRQRFADRDAGGR
                     GLQTFDLRVTIHAVTAVEAALLDLLGQHLGVPVAALLGEGQQRSEVEMLGYLFFVADR
                     NKTDLKYRSELEADDAWFRVRNEAAMTPEGVVRLAEAAHARYGFNDFKLKGGVLRGEE
                     EVEAIRALHERFPQARVTLDPNGGWRLKDAVRLLRDLHGVLAYAEDPCGAEGGFSGRE
                     VMAEFRRATGLPTATNMVATDWRQMGHSIQLQSVDIPLADPHFWTLAGSVRVAQICHE
                     WGLTWGSHSNNHFDISLAMFTHCAAAAP"
     gene            1488..2255
                     /locus_tag="P5537_14565"
     CDS             1488..2255
                     /locus_tag="P5537_14565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HRV79310.1"
                     /translation="MNPESSLAEAVPPRRRARGLAHVLVEEFARRIQAGELKPGDKLP
                     TESEIVREQGVSRTVVREAISRLQAGGLVETRHGIGSFVLAAAAAAPGTLRIDPATLR
                     TVRDIIAILELRIALETEAASLAALRRSDAHLDEMRAALDEFQAAVGDQRACVAADIR
                     FHLSIARATGNEHFADFMQHLGETIIPRARVNTAKLAGDDFAQYLYRVNREHEDIYNA
                     IRRQDPEAARAAMRTHLSNSRERLVRVQEEAERAAAG"
     gene            2336..3271
                     /locus_tag="P5537_14570"
     CDS             2336..3271
                     /locus_tag="P5537_14570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004356962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HRV79311.1"
                     /translation="MDIIFGIILPVFGTLGLGYAAARHGAFDEAANRGLSLFVFNFAL
                     PLMLFRAIAQAELPDAMPWGYLLSYYLGAFGVYALAMIGGRVLFGRRLDEQAVLGLGG
                     GFSNTGMLGIPLVMTAYGPDAALPLFVMIACHSLLLLPPTTALIEAAQGKGEARGAML
                     LKLAKSVLATPIIWGLSCGLAFALLGIEIPGPLDAVAKGLGSAATPCALFALGASLTR
                     YSLGGNLREPALLVTLKTLLHPLIVWVLATQVFDVPSLWVATGVLLAALPAGITPYLF
                     AQRYGACQSTVASAVFLSTLVSVGTLSALLFVLRP"
     gene            3390..4340
                     /locus_tag="P5537_14575"
     CDS             3390..4340
                     /locus_tag="P5537_14575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004356964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HRV79312.1"
                     /translation="MSAFLALLDFSLGVTGPIFVLLGLGVLLRRVGLITEGFIAAGSR
                     LVFVVGLPTMLFVNIARTRLADSASAGMLVFGLVATVAIWLLMEIVAGIVVHPERDRG
                     VVVQGAFRSNFGVVGLAYCGNAYGEPGLAMASLYVGVLTILVNILGVITLSRSLHRSQ
                     GPGKVLRGIATNPLILGILLALPVSAFAIPLPAVAMKSAGYIADMTLPLALLCTGATL
                     DFRSLRAEAGNTALAGFGKLVAMPLMFTLGAWAAGFRGMELGVLMLMASSPSAAASYS
                     MVRAMGGNATLAANIIALTTLGSLLTTSAGVWLLRGVGLI"
     gene            complement(4595..5170)
                     /locus_tag="P5537_14580"
     CDS             complement(4595..5170)
                     /locus_tag="P5537_14580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79313.1"
                     /translation="MFFMPSRSTPRVATTTLCMLASLVFAGGCDAGAPSAAAPSASSR
                     AGDTHRLVVCSSMEDADDTRLVLGLAADGRRVTRFEIVTPDFLWNIPGQPETPRFPAG
                     QSDASPDLAGALRFEAITDAHGELRLLDFGAPEPDAVQLEGLRGSLALHETWQNDRAL
                     GSLFHAATGNLVEVAPVQCRRSEETHAPARP"
     gene            5335..6930
                     /locus_tag="P5537_14585"
     CDS             5335..6930
                     /locus_tag="P5537_14585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 19 protein"
                     /protein_id="HRV79314.1"
                     /translation="MLVTRELLTRMGASPAHADRHLDALNAAMAVHGIDTELRIAHFL
                     AQVMHESGGLRLTEENLNYSAEGLRRVFRKYYRSDAEAAAHARQPEHIANRVYASRMG
                     NGPESSGDGYRYRGRGLIQLTGKDNYRSFAQWCGADVVTHPDWVAERYAVESAVYYWD
                     CNGLNALADVDDLGAVTRRINGGLIGYEHRLELLRTAKRTLRELAAAGTVDTAAQPAV
                     LQPSHRVGATQLTLRSAPVVADRTRIGVLNQGKEVQVLGPAGESGWVRIRVSLSGLLR
                     EGVVAERYLKALPTSRGAATVPAAPAPAAALPAAHMQQDRADITRRRDGGRAYPLGEA
                     GRPVRAGGDAASLAASVSAIVDYLAVANPAHLRYRPAGGTTYCNIYATDLAYLCGVYL
                     PRVWWTDRALLQLREGAQVAVEYGRTVRELNANSLYDWLEDHGPAFGWKREVELTALQ
                     AAANAGQVCVIVARRVDLNRPGHITVVVPETGDAKAVRNAQDEVVRPLESQAGTRNVL
                     RGAAAGAWWLNSRFQAHAFWRHP"
     gene            7079..8059
                     /locus_tag="P5537_14590"
     CDS             7079..8059
                     /locus_tag="P5537_14590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter substrate
                     binding protein"
                     /protein_id="HRV79315.1"
                     /translation="MLLKKTLFAATTAVLATLAAGVVHAAPEKPECIAPAKPGGGFDL
                     TCKLVQSALQNGYLEAPMRVTYMPGGIGAVAYNTVIANRPAEAGTVVAFSGGSFLNLA
                     IGKFGKYTEDDVKWVAAVGADYGAIIVRADSPFQSLKDLIEATRATPGKVVYGAGGSV
                     GSQDWMKSALIAREAGVDPKSMRYVAFEGGGEAMTALMGGHVQVYSGDASEVAAHLKG
                     GRVRVLAVLAPERLPGELAAIPTAIEQGYKVDWTIARGYYVGPKVADADYAWWVATFD
                     KMLASPEFDKLRAERGLFPFARTGAAATEYVKQEVQRFKKLATELGLVTQ"
     gene            8135..8578
                     /locus_tag="P5537_14595"
     CDS             8135..8578
                     /locus_tag="P5537_14595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018992865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter TctB
                     family protein"
                     /protein_id="HRV79316.1"
                     /translation="MSERIFGGVLLLVSLAGIWIGWDLQAPMSYEPVGPRAFPLLVLF
                     LLGLCAIALMLEKKSETVWAPPPVLKRIGLLFLIVLAYALLFDKLGFVIATALMTVPV
                     ARFFGGSWRQGIVGGLGLGVGMFFFFDRLLDVALPTGLWLNGILG"
BASE COUNT         1233 a         2939 c         3029 g         1387 t
ORIGIN      
        1 ggcgcggcgg cggcgcagtg ggtgaacatc gccagcgaga tgtcgaagtg gttgttggag
       61 tgcgagcccc acgtcaggcc ccattcgtgg cagatctgcg ccacgcgcac cgagccggcg
      121 agcgtccaga agtgcgggtc ggcgagcggg atgtccaccg actgcaactg gatcgaatgg
      181 cccatctggc gccagtcggt ggcgaccatg ttggtggccg tcgggagccc ggtggcgcgg
      241 cggaactcgg ccatcacctc gcggccggag aagccgcctt cggcgccgca ggggtcttcc
      301 gcgtaggcga gcacgccgtg caggtcgcgc agcaggcgca ccgcgtcctt cagccgccag
      361 ccgccgttgg ggtcgagcgt cacgcgcgcc tgcgggaagc gctcgtgcag ggcgcggatg
      421 gcttcgacct cttcctcgcc gcgcagcacg ccgcccttga gcttgaagtc gttgaagccg
      481 tagcgtgcgt gtgcggcttc ggccaggcgc acgacgcctt cgggggtcat cgcggcctcg
      541 ttgcgcacgc ggaaccaggc gtcgtcggcc tcgagttcgc tgcggtactt gagatcggtc
      601 ttgttgcggt cggcgacgaa gaacaggtag ccgagcatct cgacctcgct gcgctgctgg
      661 ccttcgccga gcaaagcggc gacgggcaca cccaggtgct ggccgagcag gtcgagcagc
      721 gcggcctcga ccgcggtgac ggcgtggatg gtcacgcgca ggtcgaaggt ctgcaggccg
      781 cggccgccgg cgtcgcgatc ggcgaagcgc tggcgcatgg cgttgaggat ggcgttccag
      841 ttgcccgtcg gctggccgac gatgaggctg cgcgcgtctt ccagcgtctg gcggatcttc
      901 tcgccgccgg gcacctcgcc caggccggtg ttgcccgcgc tgtcctcgag gatgaggatg
      961 ttgcgggtga agtaggggcc atgcgcgccg ctcaggttca gcagcatgct gtcctggccg
     1021 gcgaccggca cgacgcgcat gcgggtgacc accggggcgt ggctgacgga ctggggagag
     1081 gtcatggggt ggactcctga ggatcggtgc ggcgacttaa gatgtacgac atcctataaa
     1141 tggattgtgc ccacggcaag cacttttttg attggcacag aacttttgtt tattgcatag
     1201 cagcatgatc ctggctgaaa tttgagcatc aaggcgtttc gaggcgcgtg caaactgtgc
     1261 tgcagtgcgg taaatacagc gcaagcacaa tcttcgaagt gtgatgacta agcttgttag
     1321 gccacccatc tggcgatgat gtcagacaag cagggcgcgc cgaatgtgat ttcggtttgg
     1381 ctatagaagt cagacaacat acaattggca gatgcggaac cgctaacgga gcggtgttgt
     1441 tccgcacccg agttccctgc cacgacggcg cgcttgcgcg agaagacatg aatcccgaat
     1501 ccagccttgc tgaagcagtg cccccgcgac gccgtgcccg tggcctggcg cacgtcctcg
     1561 tcgaggaatt cgcccgccgc atccaggccg gcgagctcaa gcccggcgac aagctcccga
     1621 ccgagtcgga gatcgtgcgc gagcaggggg tcagccgcac cgtggtgcgc gaggcgatct
     1681 cgcgcctcca agcgggcggc ctggtcgaga cccggcacgg catcggctcc ttcgtgctcg
     1741 ccgctgcggc cgcggcgccg gggacgctgc gcatcgaccc cgcgacgctg cgcaccgtgc
     1801 gcgacatcat cgccatcctc gagctgcgca tcgcgctcga gaccgaggcc gcctcgctcg
     1861 cggcgctgcg ccgcagcgac gcccacctgg acgaaatgcg cgcggcgctc gacgagttcc
     1921 aggccgcggt gggggaccag cgcgcctgcg tggcggcgga catccgcttc catctgtcga
     1981 tcgcgcgcgc caccggcaac gagcatttcg ccgacttcat gcagcacctg ggcgagacga
     2041 tcatcccgcg cgcccgcgtc aacaccgcga agctggcggg cgacgacttc gcgcagtacc
     2101 tgtaccgcgt caatcgcgag cacgaggaca tctacaacgc gattcggcgc caggaccccg
     2161 aagccgcgcg cgcggcgatg cgcacccatc tctccaacag ccgcgagcgt ctggtacggg
     2221 tgcaggaaga ggccgagcgc gccgccgccg gctgaggccg caacaggcac ggctcggggc
     2281 aaggcctcag gacgacgggg acggccgccc tccccgcctg caataaggga tctctgtgga
     2341 catcatcttc ggcatcatcc tgccggtctt cggcacgctc ggcctcggct acgccgccgc
     2401 acgccacggc gccttcgacg aggcggccaa ccgtggcctg tcgctgttcg tgttcaactt
     2461 cgcgctgccg ctgatgctgt tccgcgcgat cgcgcaggcc gagctgccgg acgcgatgcc
     2521 ctggggctat ctgctgtcgt actacctcgg tgccttcggg gtatatgcgc tggcgatgat
     2581 cggtggccgg gtgctgttcg ggcgccggct cgacgagcag gcggtgctcg ggctgggcgg
     2641 gggcttttcc aacaccggca tgctcggcat cccgctggtg atgaccgcct acggtccgga
     2701 tgcggcgctg ccgctgttcg tgatgatcgc ctgccacagc ctgctgctgc tgccgcccac
     2761 caccgcgctg atcgaggccg cgcagggcaa gggtgaagca cggggcgcga tgctgctgaa
     2821 gctggcgaag agcgtgctcg ccaccccgat catctggggc ctgtcctgcg ggctggcctt
     2881 cgcgctgctc ggcatcgaga tccccggccc gctcgacgcg gtggccaagg gcctggggag
     2941 cgcggcgacg ccgtgcgcgc tgttcgcgct cggcgcctcg ctgacgcgct acagcctcgg
     3001 cggcaacctg cgcgagccgg cgctgctggt gacgctgaag accttgctgc atccgctcat
     3061 cgtgtgggtg ctcgccaccc aggtgttcga cgtgccgtcg ctgtgggtgg cgaccggcgt
     3121 gctgctggcg gcgctgccgg cgggcatcac gccctacctg ttcgcgcagc gctacggtgc
     3181 ctgccagtcc acggtggcgt cggcggtgtt cctgtccacg ctggtgtcgg tgggcacgct
     3241 gtcggcgctg ctgttcgtgc tgcggccctg aggcgggcgc cggacacggg cggacatggc
     3301 gccggaagcg aggggcgccc gccgcactga attgcatccc ctttcccgac ggcggttcgc
     3361 ataccgccgc ccaaacaaga agaccgccga tgtccgcttt cctcgccctg ctcgatttct
     3421 ccctcggcgt caccggcccg atcttcgtgc tgctcggcct cggcgtgctg ctgcgccggg
     3481 tcgggctgat caccgagggc ttcatcgcgg cgggttcgcg gctggtgttc gtcgtcggcc
     3541 tgccgaccat gctcttcgtc aacatcgcgc gcacgcggct cgcggactcg gcgagcgccg
     3601 gcatgctggt cttcggcttg gtggcgacgg tggcgatctg gctgctgatg gagatcgtgg
     3661 cgggcatcgt cgtgcatccg gagcgcgatc gcggcgtggt ggtgcagggc gccttccgct
     3721 ccaacttcgg ggtcgtcggc ctggcctact gcggcaacgc ttacggcgag ccggggctgg
     3781 cgatggcctc gctctacgtc ggcgtgttga cgatcctggt caacatcctc ggggtgatca
     3841 cgctcagccg ctcgctgcac cgcagccagg gtccgggcaa ggtcctgcgc ggcatcgcca
     3901 ccaatccgct gatcctcggc atcctgctcg cgctgccggt gtcggcgttc gcgatcccgc
     3961 tgcccgcggt ggcgatgaag tcggccggct atatcgccga catgacgctg ccgctcgcgc
     4021 tgctgtgcac cggcgcgaca ctggatttcc gcagcctgcg ggccgaagcc ggcaacaccg
     4081 cgctggccgg cttcggcaag ctggtggcga tgccgctcat gtttacgctc ggtgcgtggg
     4141 cggcgggctt ccgcggcatg gagctcggcg tgctgatgct gatggcgtcc tcgccctcgg
     4201 cggcggcgag ctattcgatg gtgcgggcga tgggcggcaa cgccacgctg gcggccaaca
     4261 tcatcgcgct gaccacgctc ggctcgctgc tcaccaccag cgcaggggta tggctgttgc
     4321 gcggggtcgg gctgatctag gggcaaagtg cgcggcgtgc tccagcggcc gctttcgcgc
     4381 ctgccggcgc tcctacagaa accgtcgcgc gtcccggagc cgcctgtggg agctgcggca
     4441 gctgcgaacc cggcggtccg gccatcgacg tgcgtgcaga actgcaccgc cgtgttcgcg
     4501 cctgccggcg ctcctacaga aaccgccgcg ggtccgggag ccgcctgtag gcgctgcggc
     4561 agccgcgaag ctccgcgcag tcttccgtgc tgcgtcacgg ccgcgccggt gcgtgcgtct
     4621 cctcggagcg ccggcactgc accggcgcga cctccaccag gttgccggtc gcggcgtgga
     4681 acagcgaacc cagggcgcga tcgttctgcc acgtctcgtg cagcgcgagc gaaccgcgca
     4741 ggccttcgag ctgcactgcg tcgggctccg gggcgccaaa gtcgagcagg cgcagctcgc
     4801 catgcgcgtc ggtgatcgcc tcgaaacgca gtgcgccggc gaggtcgggc gaggcatcgc
     4861 tctggccggc gggaaagcgc ggggtctctg gctggccggg aatgttccag aggaaatccg
     4921 gcgtgacgat ctcgaagcgg gtgacgcggc gtccgtccgc ggccaggccg agcaccagcc
     4981 gggtgtcgtc ggcgtcttcc atgctgctgc acaccacgag ccggtgagtg tctcccgccc
     5041 gggagcttgc ggacggcgca gcagcggagg gcgcgccggc atcgcagccg cccgcgaaca
     5101 cgaggctggc cagcatgcac agcgtggtgg tggcgaccct gggggtcgag cgcgagggca
     5161 tgaagaacat gggcgtcgcc tccgtccgcg agagcgggat gaggggatta tggccgaatt
     5221 tcgcgcgacc ctctcccgtt gtccgaacgc tcagccgcgc cttccccatc cgtcttgcca
     5281 accccgattc catgggctta agtgaaggca ggaacgtctt ccagggagaa tgccatgctg
     5341 gtcacgcgcg aactgctcac ccggatgggg gcctcgccag cgcatgccga tcgccacctc
     5401 gatgcgctca atgcggcgat ggcggtgcat ggcatcgaca ccgagctgcg catcgcccac
     5461 tttctcgcgc aggtgatgca cgaatcgggc ggcctgcgcc tgacggagga gaacctcaac
     5521 tattccgccg agggtctgcg cagggtcttc cgcaagtatt accgcagcga cgccgaggcg
     5581 gcggcccacg cacgccagcc cgagcacatc gccaaccgcg tctacgccag ccgcatgggc
     5641 aacggcccgg agtccagcgg cgacggctac cgctatcgcg gccgcggcct catccagctc
     5701 accggcaagg acaactaccg cagcttcgcg caatggtgcg gtgccgacgt ggtgactcac
     5761 ccggactggg tggcggagcg ctacgcggtc gagtccgcgg tgtattactg ggattgcaac
     5821 gggctgaatg cgctcgccga tgtcgacgac ctcggcgcgg tcacgcgccg gatcaacggc
     5881 gggctgatcg gatacgagca ccgtctcgag ctcctgcgca cggcaaagcg caccttgcgc
     5941 gagctggcgg cggccggcac ggtggacacc gccgcgcagc ccgcggtgct gcagccctcg
     6001 catcgcgtcg gcgccaccca gctcacgctg cgcagcgcgc cagtggtcgc cgatcgcacg
     6061 cggatcggtg tgctcaacca gggcaaggag gtgcaggtgc tcgggcccgc cggcgagtcc
     6121 ggctgggtgc gcatccgtgt gtccctgagc gggctgctgc gcgagggcgt ggtcgccgag
     6181 cgctatctca aggcgttgcc gaccagccgt ggtgcggcaa ccgtgcccgc cgccccggct
     6241 ccggccgctg cccttcctgc ggcacacatg cagcaggatc gtgccgacat cacccgccgc
     6301 cgcgacggcg gtcgagccta tccgctcggc gaagccggcc gtccggtccg tgctggcggc
     6361 gacgcggcga gcctggcggc gtcggtgtcg gcgatcgtcg attacctcgc cgtcgccaac
     6421 cccgcccatc tgcgctaccg gccggcaggc ggaaccacct actgcaacat ctacgcgacc
     6481 gatcttgcct acctgtgcgg cgtctatctg ccgcgggtgt ggtggaccga ccgcgccctg
     6541 ctgcagctgc gcgagggcgc ccaggtggcg gtcgaatacg gccgcacggt gcgcgagctc
     6601 aacgccaact cgctctacga ctggctggag gaccacggtc ctgccttcgg ctggaagcgc
     6661 gaggtcgagc tcaccgcgct gcaggcggcg gccaatgccg gccaggtgtg tgtgatcgtc
     6721 gcccgccggg tggacctcaa ccgcccgggc cacatcaccg tggtggtgcc ggagaccggc
     6781 gacgcgaagg cggtgcgcaa cgcgcaggac gaagtcgtgc gcccgctcga atcccaggct
     6841 ggtacgcgca acgtgctgcg cggggcggcg gcaggcgcgt ggtggctgaa cagccgtttc
     6901 caggcgcacg ccttctggcg gcatccgtaa ggcgtcgaac cggcagccgg atcgacgcat
     6961 ccggccgccc aatgcactga aagccaatcg aaagccctcc tccgtatcgt ccgcctcacc
     7021 ctgcgaggcg gcacgcgtcc gcctgcagcg aacacattcc gatacggagg agatcaacat
     7081 gctgctcaag aagaccctgt tcgccgccac caccgcggtg ctcgccaccc tcgccgccgg
     7141 tgtggtccac gccgcccccg agaagcccga gtgcatcgcc ccggccaagc ccggcggtgg
     7201 cttcgacctc acctgcaagc tggtgcagag cgcgctgcag aacggctacc tcgaggcgcc
     7261 gatgcgcgtc acctacatgc ccggcggcat cggcgcggtg gcctacaata ccgtgatcgc
     7321 caaccgcccg gccgaggccg gcacggtggt ggccttctcc ggcggctcct tcctgaacct
     7381 ggccatcggc aagttcggca agtacaccga ggatgacgtg aagtgggtcg ccgcggtcgg
     7441 tgccgactat ggcgcgatca tcgtgcgcgc ggactcgccc ttccagagcc tcaaggacct
     7501 gatcgaggcc acccgcgcga ctccgggcaa ggtggtttac ggcgcgggcg gttcggtggg
     7561 cagccaggac tggatgaagt cggcgctgat cgcgcgcgag gcgggggtcg atcccaagtc
     7621 gatgcgctac gtcgccttcg agggcggtgg cgaggcgatg accgcgctga tgggcggcca
     7681 tgtgcaggtg tattcgggtg acgcctccga ggtggccgca cacctcaagg gcggtcgcgt
     7741 gcgcgtgctc gcggtgctcg cccccgagcg cctgccgggt gaactggcgg cgatcccgac
     7801 cgcgatcgag cagggctaca aggtcgactg gaccatcgcc cgcggctact acgtcggccc
     7861 caaggtcgcg gatgcggact acgcctggtg ggtggcgacc ttcgacaaga tgctggcctc
     7921 gcccgagttc gacaagctgc gcgccgagcg cggcctgttc cccttcgccc gcaccggcgc
     7981 ggcggcgacc gagtacgtga agcaggaagt gcagcgcttc aagaagctcg cgaccgagct
     8041 cggcctcgtc acccagtaag cctccgccac aaaccctgcc ggcctgccgg cgcccgatcg
     8101 ggtgctatcg caggcggcgc acgggagttc gaccatgagt gaaagaatct tcggcggcgt
     8161 gctgctgctg gtgagcctgg ccggcatctg gatcggctgg gacctgcagg cgccgatgtc
     8221 ctacgagccg gtggggccgc gcgccttccc gctgctggtg ctgttcctgc tcggcctgtg
     8281 cgcgatcgcg ctgatgctcg agaagaagag cgagacggtg tgggcgccgc ccccggtgct
     8341 caagcgcatc ggcctgctgt tcctgatcgt gctcgcctac gcgctgctct tcgacaagct
     8401 cggcttcgtg atcgcgaccg cgctgatgac cgtaccggtg gcgcgcttct tcggcggcag
     8461 ctggaggcag ggcatcgtcg gcggcctcgg cctcggcgtg ggcatgttct tcttcttcga
     8521 ccgcctgctc gatgtcgcgc tgccgaccgg gctgtggctc aacggcatcc tggggtaagc
     8581 catggaaa
//
LOCUS       DAOTIN010000135         8500 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_10005_length_8500_cov_8.522084, whole genome shotgun sequence.
ACCESSION   DAOTIN010000135 DAOTIN010000000
VERSION     DAOTIN010000135.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 8500)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 8500)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8500
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_10005_length_8500_cov_8.522084"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(98..1417)
                     /locus_tag="P5537_14600"
     CDS             complement(98..1417)
                     /locus_tag="P5537_14600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HRV79317.1"
                     /translation="MASATSSSAAEGGARHGWRRWLPGGMRVRIAVSVTAMLVVLIVA
                     QSLALVRLNEEMEEEFIDGTLDEQLHYSIEHSRRLGTLIGPQTPNMTLYRFAPGEALP
                     PGLSPALAALAVGKHEDWSAGRELHVAVREADGQRYVLIYDESEHRARETAVVTTVVI
                     GGLALTALSFLLVYAIAARLTRALETLAERVEGERDGTPFAQPGLDAELLAVARALDR
                     AEARQAALLARERDFNANLSHELRTPLAGIRSDAEMLLTDPALSTKARRRAERIVATT
                     DRTATLAHSLLLLAREARPQGAEPVNLGAAVRDAWARLQAAGKEAEAVAIRIDPAAEV
                     VADPSLLALVLHNLLENALRHGEGRAIEVVLEGRQLAVCDRGPGFGSEDPMRSFERFR
                     RGGGKPGHGLGLALVQHICTACGWTVHAANRPDGGACLTIDFEPAAA"
     gene            complement(1386..>2021)
                     /locus_tag="P5537_14605"
     CDS             complement(1386..>2021)
                     /locus_tag="P5537_14605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HRV79318.1"
                     /translation="IAENLYDYLEARGHQCDYAGSIAAASALLARSVFDAVVLDRNLP
                     DGDGLALARRLRSEGRATPILVLTARDTLEDKLLGFEAGGDDYLVKPFALQELEVRLL
                     ALARRNAARAADPVLRYGALEFRAATQALHLDGRPLALPPKPLRLVAELLAQPERVFS
                     RRELELAVWGHEQDSSDNLRSVLHTLRRALGDDAPVQVVNVHGLGYKLVSR"
     assembly_gap    2022..2121
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<2122..2711)
                     /locus_tag="P5537_14610"
     CDS             complement(<2122..2711)
                     /locus_tag="P5537_14610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HRV79319.1"
                     /translation="MTAITPRQALLLSLAAALSTIAMKTGAWWLTGSIGYLSDALESV
                     VNLAGAGFALWMVSYAQRPADEDHQYGHGKAEYFSAAFEGGLIFIAALIILLTAGERL
                     LNPQPIDALGLGTLLSVGASLINFLVARVLLQVGRAHRSLALEADARHLMADVWTTAG
                     VVCGVGLAVVTGWSWLDPVVAGAVALNILREGWELMR"
     gene            complement(2716..3168)
                     /locus_tag="P5537_14615"
     CDS             complement(2716..3168)
                     /locus_tag="P5537_14615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79320.1"
                     /translation="MMTATLLSPLLLALAAGIAAPAHAAGREPASLPPQTCQSIRHEL
                     DAVATHVSEARAERAGAATAPDPYLTLARALESHLDALHANLPAPATQRAQASVLVSD
                     MRDALVLVRGATRPDARQLALQRLDADQRLYNRVLETLGCSATRPTAL"
     gene            3394..4734
                     /locus_tag="P5537_14620"
     CDS             3394..4734
                     /locus_tag="P5537_14620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HRV79321.1"
                     /translation="MNNIRFAYAGLLLLLSLLWWMADPLLPNGYEYFALRTVAINYTG
                     VIGIGVMSVGMILALRPVRVEPLLDGLDKTYRLHKWLGITGLVFAVIHWLWAQGTKWA
                     VGWGWLVKPERGPKPTLTDPVEIFFRTQRGLAESVGEWAFYAAVVLIVIALTKRFPYR
                     LFFKTHRLLAVAYLALVFHSVLLTPFAYWAQPMGIVLAVLMAGGSVAAVVSLSGRVGH
                     RRKAVGEIEELVPFPDNRVLKVAIRFKDRWPGHEAGQFAFVTFSTDEGAHPFTISSGW
                     KGDGRLFFLIKGIGDYTARLPELLRVGDLVTVEGPYGRFDFASGSVGGKRRQIWVGGG
                     IGITPFIARMKALAVAPDGREVDLFYSTAEPDEGFIARLQRDAQAACVRLHVLVSARD
                     GRLDVARICDTVPGWAEADVWFCGPGRFGQALREGFVARGLPAADFHQELFDMR"
     gene            4910..5326
                     /locus_tag="P5537_14625"
     CDS             4910..5326
                     /locus_tag="P5537_14625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1924 domain-containing protein"
                     /protein_id="HRV79322.1"
                     /translation="MNSQFRAFALLCGLAASAGALAAPSAALLERYAAEARAADPAFA
                     GFSAARGEALHRTRHGLGKPDTPACTSCHGENARSAGQTRTGKAIEPMAVSVSATRYG
                     DPAKVEKWFKRNCNEVLGRECSAREKGDWLAWMSTQ"
     gene            5347..5838
                     /locus_tag="P5537_14630"
     CDS             5347..5838
                     /locus_tag="P5537_14630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diheme cytochrome c"
                     /protein_id="HRV79323.1"
                     /translation="MKTPALRPLALGAAAIAVTLMLLGRAQAGDDDFYPPVTDPLTVQ
                     ECASCHIAFPASMLPAASWRRMMGELENHFGDDASVDADTTAAITRYLVDHAGDARGQ
                     PGKLLRGLRPGDAPLRITELPKWVHEHDEVPRSEWTRKDVGSKANCTACHIDAAKGYF
                     EDD"
     gene            5854..7182
                     /locus_tag="P5537_14635"
     CDS             5854..7182
                     /locus_tag="P5537_14635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HRV79324.1"
                     /translation="MKRFLSAFIALVGLAWGVEMLSATGAVASAPGNPWAVREHALTL
                     TGLGSFALMSLAMVLATRPARLERFFGGMDRIYRVHKWAGILAVGFAALHWLVELSDD
                     LIKTLWGREGRLPKDHGGGLLEAMRDVAEELGEFAIYALLAMLVLTLWKRFPFRIWRY
                     VHKGMPVLYLALAFHAAFLAPLDYWTQPVGVLLASLIVAGSVASVRVLAGRIGQDRRV
                     GGVVESVRDAGAGVTEVVCRLDEGWRGHRPGQFAFATFDRLEGAHPFTIAGTDRGDRR
                     VRFQIKALGDYTRGLAQRLQPGRPMQVEGPYGCFDLPLSLDGREQIWIAGGIGVTPFL
                     AWLEALQARPEQAPDVDFYYSVREHATDPFVARLQALCANLPAVRLHVISGARNERLT
                     AATLRDRPRAGAAPEIWFCGPRGLATSLREGLRGLGMGGARFHQEAFEMR"
     gene            complement(7179..7643)
                     /locus_tag="P5537_14640"
     CDS             complement(7179..7643)
                     /locus_tag="P5537_14640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic heavy metal sensor"
                     /protein_id="HRV79325.1"
                     /translation="MKTTKPGMALLLSVALNLGVLGAVLLDRLGPGASATPAPPLHRV
                     LALDEAQRARWEAVEAPFLQQFEVAAVRLERHRHALVEALFAESIDPLRIEAERAAIA
                     ELQQAQQRLIIEQLIAERAILDVRQREQLLGLLLAQPPARTTVEDLHARPTR"
     gene            complement(7640..8020)
                     /locus_tag="P5537_14645"
     CDS             complement(7640..8020)
                     /locus_tag="P5537_14645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma factor"
                     /protein_id="HRV79326.1"
                     /translation="MRALRDAFAALPAIRLEVDLAAQLVDRLQAGATPAARKRRQSPW
                     WVRWADRLRPPTPWRFGLSPFAGSVAAVGLGLWLGGLLMELEAPRSPPAANTTLAAMS
                     VFGAVPPGNLCPRAGACGASGSTR"
     gene            complement(8172..>8500)
                     /locus_tag="P5537_14650"
     CDS             complement(8172..>8500)
                     /locus_tag="P5537_14650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HRV79327.1"
                     /translation="RNAALDQVRRRQVVRFAPLEEGLEVADEAPGPEARYASRQRQVQ
                     LERALRRLAAEHREILLLREVEGLAYGELASVLGIAEGTVKSRLARARRALLEHFDPH
                     TGASHE"
BASE COUNT         1152 a         2938 c         3106 g         1204 t
ORIGIN      
        1 aggatcggcg caatctacgc aggcgcgcgt gaggaaagcg tgatgcgggt gtgaggaaag
       61 tgtgagcgcg atctgcctgc gctgcgcccg gtgggcctca agcggcggcg ggttcgaagt
      121 cgatcgtcag gcaggcgccg ccgtcgggac ggttggcggc gtgcaccgtc catccgcagg
      181 cggtgcagat gtgctgcacc agtgccaggc cgaggccgtg ccccggcttg ccgccgccgc
      241 ggcggaagcg ctcgaagctg cgcatcgggt cctcgctgcc gaagccgggg ccgcggtcgc
      301 acacggcaag ttgccgccct tccagcacga cctcgatcgc acgcccttcg ccgtggcgca
      361 gcgcgttctc cagcaggttg tgcagcacca gcgccagcag gctggggtcg gcgacgacct
      421 cggccgcagg gtcgatgcgg atggccaccg cctcggcctc cttgccggcc gcctgcagtc
      481 gcgcccaggc gtcgcgcacc gcggcgccca ggttgaccgg ctcggccccc tgcggccggg
      541 cctcgcgggc gagcaacagc aggctgtggg cgagcgtggc ggtgcggtcg gtggtggcga
      601 cgatgcgttc ggcgcggcgg cgggccttgg tcgacagcgc ggggtcggtc agcagcatct
      661 cggcgtcgct gcggatgccg gcgagcgggg tgcgcagttc gtgcgacagg ttggcgttga
      721 agtcgcgctc gcgcgcgagc agggccgcct ggcgcgcttc ggcgcggtcg agcgcgcgcg
      781 ccacggcgag gagctcggcg tcgagtccgg gctgggcgaa gggcgtgccg tcgcgctccc
      841 cctcgacgcg ctcggcgagc gtctccagag cgcgtgtgag ccgggcggcg atggcataga
      901 cgaggaggaa ggacagggcg gtcagggcca gcccgccgat caccaccgtg gtgacgacgg
      961 cggtctcgcg cgcgcggtgc tcggattcgt cgtagatcag tacgtagcgc tggccgtccg
     1021 cctcgcgcac cgcgacgtgt agctcgcgcc cggccgacca gtcctcgtgc ttgccgaccg
     1081 ccagcgcggc cagcgccggg ctcaggcccg gcggcagcgc ctcgcccggc gcgaagcggt
     1141 agagcgtcat gttcggcgtc tgcggcccga tcagggtgcc gagccggcgg ctgtgctcga
     1201 tgctgtagtg cagctgctcg tcgagcgtgc cgtcgatgaa ctcctcttcc atctcctcgt
     1261 tgagccgcac cagggcgagc gactgcgcca cgatgagcac gaccagcatc gcggtgaccg
     1321 agaccgcgat gcgcacgcgc atgccgccgg gcagccagcg ccgccagcca tggcgcgcac
     1381 cgccctcagc ggctgacgag cttgtagccg aggccatgga cattcaccac ctgaacgggc
     1441 gcgtcgtcgc cgagggcgcg acgcagggtg tgcagcacgc tgcgcaggtt gtcgctgctg
     1501 tcctgctcgt ggccccacac cgcgagctcc agctcgcggc gggagaacac gcgctcgggc
     1561 tgggcgagca gttcggcgac caggcgcagg ggcttcggtg gcagcgcgag tggcctgccg
     1621 tcgaggtgca gcgcctgggt cgcggcgcgg aactccagcg cgccgtagcg caacaccgga
     1681 tcggccgcgc gcgcggcatt gcgccgcgcc agcgccagca ggcgcacctc gagctcctgc
     1741 agcgcgaagg gcttgaccag gtagtcgtcg ccgccggcct cgaagccgag cagcttgtct
     1801 tccagcgtgt cgcgcgcggt cagcaccaga atcggcgtgg cgcggccctc gctgcgcagc
     1861 cggcgcgcaa gcgcgaggcc gtcgccgtcg ggcaggttgc ggtcgagcac cacggcgtcg
     1921 aacacgctgc gcgcgagcag ggccgaggcc gccgcgatcg agccggcgta gtcgcactgg
     1981 tggccgcgcg cctcgaggta gtcgtagagg ttctcggcga tnnnnnnnnn nnnnnnnnnn
     2041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2101 nnnnnnnnnn nnnnnnnnnn ncgcatcagc tcccagccct cgcgcaggat gttgagcgcg
     2161 accgcgccgg cgaccaccgg gtcgagccag ctccagccgg tgacgaccgc caggccgacg
     2221 ccgcacacca cgccggcggt ggtccacacg tcggccatca ggtggcgcgc gtcggcctcg
     2281 agggcgagcg agcggtgcgc gcggccgacc tgcagcagca cgcgcgcgac gaggaagttg
     2341 atcaggctcg cgccgaccga cagcagggtg ccgagcccca gtgcgtcgat cggctgcgga
     2401 ttgagcaggc gctcaccggc ggtgagcagg atgatcagcg cggcgatgaa gatcagcccg
     2461 ccctcgaacg cggcggagaa gtattcggcc ttgccatggc cgtactggtg atcctcgtcg
     2521 gcggggcgct gcgcgtagga caccatccac aacgcaaaac cggcgccggc caggttgacc
     2581 accgactcga gcgcgtcgga caggtagccg atcgagccgg tcagccacca ggcgccggtc
     2641 ttcattgcga tggtgctgag cgcggcggcg agcgagagca gcagggcctg gcgcggcgtg
     2701 atggcggtca tcggttcaca gggcggtggg tcgggtggcg gagcacccga gggtctccag
     2761 cacccgattg tagagccgtt gatcggcgtc gaggcgctgc agcgcgagct ggcgggcatc
     2821 ggggcgggtt gcgccgcgca ccagcaccag ggcgtcgcgc atgtcgctca ccagcacgct
     2881 ggcctgcgcg cgctgcgtcg ccggtgccgg caggttggcg tgcaaggcgt cgaggtggga
     2941 ctcgagcgcg cgcgccagcg tcaggtaggg gtcgggcgcc gtcgctgcgc cggcgcgctc
     3001 cgcgcgcgcc tcgctcacat gggtcgcgac cgcatcgagc tcatggcgaa tcgactggca
     3061 tgtttgtggc ggcagggatg ccggttcacg ccccgcggcg tgcgcggggg cggcgatgcc
     3121 ggcggcaagt gccagcaaca ggggggagag cagggtcgcg gtcatcattg gcagggctcc
     3181 gtggtgagga cagcgcggag catggcgctg ccatccttaa ctggagctga accgactgcc
     3241 gccgggcgtg gccggcggca ctgcggcgct ttcgtttgcg ctgcgacaag gcgggccagc
     3301 ggccgccggg gcacaatcaa agcagtcggt ccgatgacgc gcgcacccta tgcaccgcaa
     3361 cggacgcggg atctcgagcg aatggagcag acgatgaaca acatccggtt tgcgtacgct
     3421 gggctgttgc tgttgctcag cctgctgtgg tggatggccg atccgctgtt gcccaacggc
     3481 tatgaatact ttgccctgcg cacggtggcg atcaactaca ccggcgtgat cggcatcggc
     3541 gtcatgagcg tgggcatgat cctggcgctg cgcccggtgc gggtggagcc gctgctcgac
     3601 gggctggaca agacctaccg cctgcacaag tggctgggca tcaccggcct ggtgttcgcg
     3661 gtgatccact ggctgtgggc gcagggcacg aagtgggcgg tgggctgggg ctggctggtg
     3721 aagcccgagc gggggccgaa gccgacgctc accgacccgg tcgagatctt cttccgcacc
     3781 cagcgtggcc tcgcggaatc ggtgggcgag tgggccttct acgcggcggt ggtgctgatc
     3841 gtgatcgcgc tcaccaagcg cttcccctac cgcctgttct tcaagaccca ccgcctgctg
     3901 gccgtcgcct acttggcgct ggtcttccac tcggtgctgc tgacgccctt tgcctactgg
     3961 gcgcagccga tgggcatcgt gctcgccgtg ctgatggccg gcggcagcgt cgccgccgtg
     4021 gtgtccctgt ccggacgcgt cggccatcgg cgcaaggcgg tgggcgagat cgaggagctg
     4081 gtgcccttcc ccgacaaccg cgtgctcaag gtggcgatcc gcttcaagga ccgctggccg
     4141 gggcacgaag ccgggcagtt cgccttcgtc accttttcga cggacgaagg ggcgcacccc
     4201 ttcaccatct cctcgggctg gaagggcgac ggccggctgt tcttcctgat caagggcatc
     4261 ggcgactaca ccgcccgcct gcccgaactg ctccgggtcg gcgacctcgt caccgtcgaa
     4321 ggcccctatg gccgcttcga tttcgccagc ggcagcgtcg gcggcaagcg ccggcagatc
     4381 tgggtcggcg gcggcatcgg catcacgccc ttcatcgccc gcatgaaggc gctcgcggtg
     4441 gcgcccgacg ggcgcgaggt cgatctgttc tacagcaccg ccgaacccga cgaaggcttc
     4501 atcgcccgcc tgcagcgcga tgcgcaggcg gcgtgcgtga ggctgcacgt gctggtgagc
     4561 gcgcgcgacg gccgcctcga cgtggcgcgc atctgcgaca cggtgccggg atgggccgag
     4621 gcggacgtct ggttctgcgg acccggccgt ttcggccagg ccctgcgcga gggcttcgtc
     4681 gcccggggcc tgccggcggc cgacttccac caggaactct tcgacatgcg ctgagcgcgg
     4741 gcagcgtgcg ggcgcatcgg cgcccgcgcc cgccgctcct tggcgcacgc tctttctccg
     4801 ttcaggttcg attcagtggc gcacttgcac actgggctcg cgattccgga cggctggcat
     4861 ccgcgatgcc cgtccggtcg agtcctcagc ccggatcaag gaacgaacca tgaacagcca
     4921 attccgcgcg tttgcgctgc tgtgcggcct cgccgccagt gccggggcgc tcgccgcccc
     4981 gagcgccgcc ctactggagc gctacgccgc cgaggcgcgc gccgccgacc ccgcctttgc
     5041 gggtttttcc gctgcacgcg gcgaagccct gcaccgcacc cgccacggcc tcggcaagcc
     5101 cgacacgccc gcctgcacct cctgccatgg cgagaacgcg cgctcagccg gccagacccg
     5161 caccggcaag gccatcgagc cgatggcggt gtcggtgtcg gccacgcgct acggcgatcc
     5221 ggcgaaggtc gaaaaatggt tcaagcgcaa ctgcaacgag gtgctcggcc gcgagtgcag
     5281 cgcacgcgag aagggcgact ggctcgcctg gatgagcacc caataacgcc gctccggaga
     5341 cccgccatga agacccccgc ccttcgcccc ctcgccctcg gtgccgccgc gatcgccgtg
     5401 accctcatgc tgctcggccg cgcccaggcc ggcgacgacg acttctatcc gccggtcacc
     5461 gacccgctca ccgtgcagga gtgcgcgagc tgccacatcg cctttccggc gtcgatgctg
     5521 cctgcggcgt cgtggagacg catgatgggc gaactggaga accatttcgg cgacgacgcc
     5581 agcgtcgatg ccgacaccac cgccgcgatc acccgctacc tcgtcgatca cgccggcgac
     5641 gcgcgcgggc agccgggcaa gctgctgcgc ggcctgcgcc ccggcgatgc ccccctgcgc
     5701 atcaccgaac tgccgaagtg ggtgcacgag cacgacgagg tcccgcgctc cgagtggacc
     5761 cgcaaggacg tcggcagcaa ggccaactgc accgcgtgcc acatcgacgc cgcgaagggc
     5821 tacttcgagg acgactgaag gagggacagg atcatgaaac gctttctgtc cgccttcatc
     5881 gccctggtcg gcctggcctg gggcgtggaa atgctgtcgg cgacgggcgc cgtcgccagc
     5941 gcgccgggca atccctgggc ggtgcgcgag cacgcgctga cgctcaccgg cctggggtcc
     6001 ttcgcgctga tgtcgctggc gatggtgctc gccacccgtc cggcccggct ggagcgtttt
     6061 ttcggcggca tggaccgcat ctaccgtgtg cacaaatggg ccggcatcct cgcggtcggc
     6121 ttcgcggcac tgcactggct ggtcgagctc tccgacgacc tcatcaagac gctgtggggg
     6181 cgcgaggggc gcctgcccaa ggatcacggc ggcggcctgc tcgaagccat gcgcgacgtc
     6241 gccgaggagc tgggcgagtt cgcgatctac gcgctgctgg cgatgctggt gctgacgctg
     6301 tggaagcgct tcccgttccg gatctggcgt tacgttcaca aggggatgcc ggtgctgtac
     6361 ctggcgctcg ccttccatgc cgccttcctc gcgccgctcg actactggac gcaaccggtc
     6421 ggcgtgctgc tggcgagcct gatcgtcgcc ggcagcgtcg ccagcgtgcg ggtgctggcc
     6481 gggcgcatcg gccaggaccg ccgcgtcggc ggcgtggtgg agtcggtccg cgacgccggc
     6541 gcgggcgtca ccgaggtggt ctgccggctc gacgagggct ggcgcggaca ccggccgggg
     6601 cagttcgcct tcgcgacctt cgatcgtctg gagggcgcgc atcccttcac gatcgccggc
     6661 accgaccgcg gcgaccgtcg ggtgcgcttc cagatcaagg ccctgggtga ctacacccgc
     6721 ggcctcgcgc agcgcctgca gccgggtcgg cccatgcagg tcgaaggacc ctatggatgc
     6781 ttcgatctgc cgctgtcgct ggacgggcgg gagcagatct ggatcgccgg cggcatcggc
     6841 gtgacgccct tcctcgcctg gctcgaggcg ctgcaggcga ggccggagca ggcgcccgac
     6901 gtcgatttct actacagcgt gcgcgagcac gcgaccgacc ccttcgtcgc ccgcctccag
     6961 gccttgtgcg cgaacctgcc cgcggtgcgc ctgcacgtga tcagcggcgc ccgcaacgag
     7021 cgcctcaccg cggcgacgct gcgcgaccgc ccgcgcgcgg gcgcggcgcc ggagatctgg
     7081 ttctgcgggc cccgcggcct cgccaccagc ctgcgcgagg gactgcgcgg actcggcatg
     7141 ggcggcgcgc gcttccacca ggaggcgttc gagatgcgct agcgcgtcgg gcgcgcgtgc
     7201 aggtcctcga ccgtggtgcg tgccggcggc tgggcaagga gcaggccgag cagctgctcg
     7261 cgctggcgca cgtcgaggat cgcgcgctcg gcgatcagct gctcgatgat caggcgctgc
     7321 tgggcctgct gcagctcggc gatcgccgca cgctcggctt cgatgcgcag cgggtcgatc
     7381 gactcggcga agagcgcttc gacgagggcg tggcggtgac gctccaggcg gacggcggcc
     7441 acctcgaact gttgcaggaa gggcgcttcg accgcctccc agcgcgcgcg ctgcgcctcg
     7501 tcgagcgcca atacccgatg aaggggcggc gccggcgtgg cggaggcacc cggcccgagc
     7561 cgatccagca gcacggcgcc gagcacgccg aggttgagcg cgaccgacag cagcagcgcc
     7621 attccaggct tggtggtctt catcgcgtgc tcccgcttgc gccgcaggcc ccggcccgcg
     7681 gacagagatt tcccggtggg acggcgccga acacgctcat ggcggccagc gtcgtgttcg
     7741 ctgcaggcgg cgaccgcggc gcttcgagct ccatcagcag tccgcccagc cacagcccga
     7801 gcccgacggc cgcgacggaa ccggcgaacg gagagaggcc gaagcgccag ggcgtcggcg
     7861 ggcggagtcg atccgcccag cgcacccacc aggggctctg ccggcgcttg cgcgcggccg
     7921 gcgtcgcgcc cgcctgcagg cggtcgacca gctgtgctgc cagatcgacc tcgaggcgga
     7981 tggcggggag cgccgcaaag gcgtcgcgca gggcgcgcaa ttcggcgagc cggcgcgtgc
     8041 agcgcgggca gcccgcgcag tgcgcgatca gtccggtgcc ggcctcggag ggcagggccg
     8101 catcggcgag ggccgacagc gcttcgtcgg cggggcacgg cccggaaggg caggaccctg
     8161 tgggacaaga gctattcatg ggaggctccg gtgtgcgggt cgaaatgttc gagcaaggcg
     8221 cggcgtgcgc gtgcgaggcg ggatttcacc gtgccttcgg cgatgccgag gacgctcgcc
     8281 agttcgccgt aggccaggcc ctcgacctcg cgcagcagca ggatctcgcg gtgctcggcg
     8341 gcgagccgcc gcaacgcgcg ctcgagttgg acctggcgtt gtcggctggc atagcgggcc
     8401 tccggccccg gggcctcgtc ggcgacctcc aggccttcct ccagcggcgc gaagcgcacg
     8461 acctgccggc ggcgcacctg gtcgagcgcc gcgttgcgcg
//
LOCUS       DAOTIN010000136         8384 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_10208_length_8384_cov_9.023412, whole genome shotgun sequence.
ACCESSION   DAOTIN010000136 DAOTIN010000000
VERSION     DAOTIN010000136.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 8384)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 8384)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8384
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_10208_length_8384_cov_9.023412"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..2293
                     /locus_tag="P5537_14655"
     CDS             <1..2293
                     /locus_tag="P5537_14655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="Hsp70 family protein"
                     /protein_id="HRV79328.1"
                     /translation="GAARLAGLPRLRLLEEPQAAFHDWLFRHRERLATELAQSRLLLV
                     CDVGGGTTDLTLIQVEPAADGVSPPRLTRIGVGDHLMLGGDNMDLALAHLVEQRLLAS
                     GERLSAAQLSQLVQRCRAAKEQLLAADAPEQVKVTLLGAGARLIGAARSTELRRDEVL
                     GLVVDGFLPVVATHEAPRRRRAAIVEFGLPYPADPAISRHLAAFLQRHGQVARAALGM
                     PAAEAGGNTAGDADAIAVPPAIPDTLLLNGGVFRADAISARLEDLLAHWRGAPPRVLH
                     NDAPDLAVARGAVAFALVRAGRAGLGPCIGGGSARSYFLVLEEGGEAARAICVLPRGT
                     ESGTEVALPERRFALRLGQAVRFHLVSSTSDSAWQAGELVELAADDFIHLPPLATRLP
                     ATAAGRRENVTVRLVACLTEVGTLEMQCVAIDDDTQRWQLAFQVRAEAEAPATEAAAG
                     AHPRLAQAIALIDEVFGGQARELDAKAVRQLRARLERVLGRRDDWDMALLRALFDALL
                     ERARRRRRSAEHERVWLNLAGYCLRPGLGAALDDWRIDQLWPLFGQGLQYVREGNNWS
                     EWWTLWRRCAGGLDEARQLQVLEVLAGHLEDTDAARRRGDPVQGSYDDMVRLAAALER
                     VPAMHRSEVGKWLLERLARPAEKAHTWWALGRVGARESLYGSAHTVVPPETAAEWLQA
                     VLALDWKAVEPAAFAAAQLARLTGDRARDLPPELRDEVARRLAAMRAPQSWITMVREV
                     VSLDDADRRRSFGEALPPGLRLL"
     gene            complement(2356..2670)
                     /locus_tag="P5537_14660"
     CDS             complement(2356..2670)
                     /locus_tag="P5537_14660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HRV79329.1"
                     /translation="MPILLQVDFPYQGPWGEDMAQAMQGLAQSIAQEPGLLWKIWTEN
                     RDTGEAGGIYLFADRADAERYLEMHCARLLGFGVPEVHAKLFEVNAPLSAIDRAPLAG
                     LK"
     assembly_gap    3118..3217
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <3218..3470
                     /locus_tag="P5537_14665"
     CDS             <3218..3470
                     /locus_tag="P5537_14665"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="MGMT family protein"
                     /protein_id="HRV79330.1"
                     /translation="GTPFQIRVWSALMRIPRGRLLSYRQLAALLGMPAAPRSVGSAIA
                     ANTLGYLVPCHRLIRADGDAGEFRWGSERKLAMLAWEAS"
     gene            3619..4140
                     /locus_tag="P5537_14670"
     CDS             3619..4140
                     /locus_tag="P5537_14670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004312764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF45 domain-containing protein"
                     /protein_id="HRV79331.1"
                     /translation="MNTRRSPDYLAGYPPALVQQVRTLIEQGGLADALRRRYPQAHAV
                     RSNSALHDYVQALKAAHLRSAPPLAKVRFDNTLHVIRNALGTHTAISRVQGARLQAKR
                     EIRIATLFRTAPEAFLRMIVVHELAHLRVREHDKAFYQLCQHMEPDYHQYEFDLRTYL
                     AYRDAGGEAIWEA"
     gene            complement(4666..6840)
                     /gene="katG"
                     /locus_tag="P5537_14675"
     CDS             complement(4666..6840)
                     /gene="katG"
                     /locus_tag="P5537_14675"
                     /EC_number="1.11.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004362372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004096 - catalase activity [Evidence
                     IEA];
                     GO_function: GO:0004601 - peroxidase activity [Evidence
                     IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catalase/peroxidase HPI"
                     /protein_id="HRV79332.1"
                     /translation="MSENSTNTAGKCPVMHGGNTASKDSVMAWWPKALNLDILHQHDS
                     KTNPLGAGFDYREELKKLDVDALKNDLKALMTDSQEWWPADWGHYGGLMIRMAWHAAG
                     TYRIADGRGGAGTGNQRFAPLNSWPDNGNLDKARRLLWPIKRKYGNKISWADLIILAG
                     NMAYESMGFKTFGFAFGREDIWHPEKDIYWGSEKEWLAPSGSEGSRYSGQRDLENPLA
                     AVMMGLIYVNPEGVDGKPDPLKTAHDMRVTFARMAMNDEETVALTAGGHTVGKAHGNG
                     SAALLGPAPEGADLEEQGFGWMNHTTRGVGRDTVTSGIEGAWTSKPTQWDNGYFDMLF
                     KHDWWLQKSPAGAWQWEPLNIAEEDMPVDVEDPSIRRKPMMTDADMALRFDPEYRKIA
                     ERFRNDQAYFEEVFARAWFKLTHRDMGPKARYIGPDVPAEDLIWQDPVPAGNTNYDVA
                     AVKAKIAAAGLSVGDMVATAWDSARTFRGSDYRGGANGARIRLAPQKDWEGNEPARLA
                     RALAAYEKIAAETGASVADVIVLGGNVGLEQAIKAAGFNVDVPFAPGRGDASQAQTDV
                     ESFEVLEPVHDGFRNWQKKDYVVQPEEMLLDRAQLLGLTAPEMTVLIGGLRVLGTNHG
                     GSKHGVFTDRVGALTNDFFVNLTDMRYSWKPTGRNSYDIVERKSGAKKWTATRVDLVF
                     GSNSILRAYAEVYAQDDNQEKFVRDFVAAWTKVMNADRFDLR"
     gene            complement(7187..7795)
                     /locus_tag="P5537_14680"
     CDS             complement(7187..7795)
                     /locus_tag="P5537_14680"
                     /inference="COORDINATES: protein motif:HMM:TIGR02595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-CTERM sorting domain-containing protein"
                     /protein_id="HRV79333.1"
                     /translation="MKRTLLVLTLLGLSATAAQAASITTVVSANGNGGNYGGSLSVLN
                     DGIFPTEGSQWNLADKVSWNGKGNRFVFAFGDLYRIDSVRLSVDNNDGYLLEYSTDYS
                     AWASLLTVSSGVGEIGWGMDTMATDPSDSEYVSQLAFTPREARYVRIQATDGDNSYSI
                     GEVAFTGERADNGSTNPVPEPAGLALIALGLAGMGLARRRRV"
BASE COUNT         1225 a         2989 c         2801 g         1269 t
ORIGIN      
        1 gggggcggcc cgcctcgccg gcctgccgcg cctgcgcctg ctggaggagc cgcaggctgc
       61 cttccacgac tggcttttcc gccaccgcga acggctcgcc accgagctgg cgcagtcccg
      121 cctgctgctg gtgtgcgacg tcggcggcgg caccaccgac ctcaccctga tccaggtcga
      181 gcctgccgcg gacggcgtct cgccgccgcg cctgacccgc atcggcgtcg gtgaccacct
      241 gatgttgggc ggcgacaaca tggacctggc gctcgcccac ctagtggagc agcgcctgct
      301 cgcgagcggc gaacgcctgt ccgccgccca gctctcgcag ctggtgcagc gctgccgggc
      361 ggcgaaggag cagctgctcg ccgccgacgc gccggaacag gtcaaggtca ccctgctcgg
      421 cgccggcgcg cgcctgatcg gcgcggcgcg ctcgaccgag ctgcgccgcg acgaggtcct
      481 gggcctggtg gtggacggct tcctgcccgt ggtcgcgaca cacgaggcgc cccggcgccg
      541 gcgcgccgcg atcgtcgagt tcggcctgcc ctatcccgcc gacccggcga tcagccgcca
      601 cctcgccgcc ttcctgcagc gccacggcca ggtcgcacgc gcggcgctcg gaatgcccgc
      661 tgcggaggcg ggcggaaata cggcgggcga tgcggacgca atcgcggtcc cgcccgcgat
      721 ccccgacacc ctgctgctca acggcggcgt gttccgcgcc gacgcgatct ccgcccgcct
      781 ggaagacttg ctcgcgcact ggcgcggagc accgccccgc gtgctgcaca acgatgcccc
      841 cgatctcgcc gtcgcccgcg gcgcggtggc cttcgcgctc gtgcgcgccg ggcgcgccgg
      901 ccttggcccc tgcatcggcg gcggctcggc gcgcagctac ttcctggtgc tggaggaggg
      961 cggcgaggcc gcgcgcgcga tctgcgtgct gcctcgcggc accgaatccg gcaccgaggt
     1021 cgcgctcccc gagcgccgct tcgcgctgcg tctcggccag gcggtgcgct tccacctcgt
     1081 ctcctccacc agcgacagcg cgtggcaggc gggcgagctg gtcgagctcg ccgccgacga
     1141 cttcatccac ctgcccccgc tcgccacccg cctgcccgcc accgccgccg gccgccgcga
     1201 gaacgtcacc gtgcgcctgg tcgcctgcct gaccgaggtc ggcacgctgg agatgcagtg
     1261 cgtggcgatc gacgacgaca cccagcgctg gcagctcgcc ttccaggtgc gcgccgaggc
     1321 cgaggcaccg gccaccgagg ccgcggccgg cgcccatccg cgcctggcgc aggccatcgc
     1381 cctcatcgac gaggtcttcg gtgggcaggc gcgcgagctg gacgccaagg cggtgcgcca
     1441 gctgcgcgcc cgcctcgagc gcgtgctcgg ccgccgcgac gactgggaca tggcgctgct
     1501 gcgcgcgctc ttcgacgccc tgctcgagcg cgcgcgccgg cgccggcgct cggcggagca
     1561 cgagcgcgtg tggctcaacc tcgccggcta ctgcctgcgc ccgggcctcg gcgcggcgct
     1621 cgacgactgg cgcatcgacc agctgtggcc cctgttcggc cagggcctgc agtacgtgcg
     1681 cgagggcaac aactggagcg aatggtggac gctgtggcgg cgctgcgccg gcggcctcga
     1741 cgaggcccgc cagctgcagg tcctggaggt gctggccggc catctggagg acaccgacgc
     1801 cgcccgccgc cgcggcgacc cggtgcaggg cagctacgac gacatggtgc gcctggccgc
     1861 cgcgctcgag cgcgtaccgg cgatgcaccg cagcgaggtc ggcaagtggc tcctcgagcg
     1921 cctcgcccgc cccgccgaga aggcgcacac gtggtgggcg ctcggccgcg tcggcgcgcg
     1981 cgagtcgctc tacggcagcg cgcacacggt ggtgccgccg gagaccgccg ccgagtggct
     2041 gcaggccgtg ctcgcgctcg actggaaggc cgtggagccc gccgccttcg ccgcggccca
     2101 gctcgcccgc ctcaccggcg accgcgcacg cgacctccca cccgagctgc gcgatgaggt
     2161 cgcccgccgc ctggccgcca tgcgcgcccc gcagagctgg atcaccatgg tgcgcgaggt
     2221 ggtcagcctc gacgacgccg accgccgccg cagcttcggc gaggcgctgc cgccgggcct
     2281 acggctgttg tgaaacgccg cggtcgatga aggcgtggcg ccgtcggtgc ctcggcaccg
     2341 acggcgcccg cgcgctcact tcaggccggc gagcggcgcg cggtcgatcg ccgacagtgg
     2401 cgcattgacc tcgaacagct tcgcatgcac ctcgggcacg ccgaagccga gcaggcgcgc
     2461 gcagtgcatc tccaggtagc gctcggcgtc ggcgcggtcg gcgaagaggt agatcccgcc
     2521 ggcctcgccg gtgtcgcggt tctcggtcca gatcttccac agcaggccgg gctcctgcgc
     2581 gatggactgc gccaggccct gcatggcctg cgccatgtcc tcgccccagg ggccttggta
     2641 agggaaatcg acttgaagaa ggatgggcat ggggagctcc tgggtgtcgg ggccggaggg
     2701 aaaggcggct cgggctgcgg cgggacgaca caacacgcct tcgccgaggc ttgcggcggt
     2761 tcgcgactcg tcggtcattc taccgtctcg acgcgaacgt tcggccatga cgccgaccga
     2821 agcgccgcgt tcgcgcctgc cggccctcct acgccgaggg tcggcgtggc ggcggttcgg
     2881 ttctgtagga gcgccggcag gcgcgaatgc ggccgctccg aagcgaagct ttcgaccaac
     2941 gcccgctacc cttgaccaac caggccatct tccctcaact tccatccgcc ctgccccctt
     3001 cgcaccgtca cccacgatgc ccgcctccac cgcgctccac ttcgaaacca tcgcccgcgc
     3061 gatcgccttc gtgcgcgccc atccccacct cccgcccgag gcggtcgcgg aggctctnnn
     3121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnncgg cacgcccttc cagatccgcg
     3241 tctggtccgc cctgatgcgc atcccgcgcg gccgcctgct gtcctaccgc cagctcgccg
     3301 ccctgctcgg catgccggcg gcgccacgca gcgtcggcag cgcaatcgcg gccaacaccc
     3361 tcggctacct cgtcccctgc catcgcctga tccgcgcgga cggcgatgcg ggcgagtttc
     3421 gctggggcag cgagcgcaag ctggctatgc tggcttggga ggcgtcgtga gcgcgctcgc
     3481 cgcccgcgat aaagcgcgtg ccttcgcggg ggaagaggtc gcgcagcgcg cggagagtcg
     3541 tcccgcgcgc gcacccgcac ggccgtgcga agcgacgcgc cttgccgcca cgaagcgagg
     3601 cgaacggaga ggagcacggt gaatacgcga cgcagtcccg actatctggc cggctacccg
     3661 ccggcgctgg tgcagcaggt gaggacgctg atcgagcagg gcgggctggc agacgcgctg
     3721 cgccggcgct acccgcaggc gcacgcggtg cgttcgaaca gcgcgctcca cgactacgtg
     3781 caggcgctca aggccgcgca cctgcgcagc gcgccgccgc tcgccaaggt gcgcttcgac
     3841 aacaccctgc acgtgatccg caacgcgctc ggcacccaca ccgcgatctc gcgcgtgcag
     3901 ggcgcgcgcc tgcaggccaa gcgcgagatc cgcatcgcca ccctgttccg cacggccccg
     3961 gaggccttcc tgcgcatgat cgtggtgcac gagctcgccc acctgcgcgt gcgcgagcac
     4021 gacaaggcct tctaccagct ctgccagcac atggagcccg actaccacca gtacgagttc
     4081 gacctgcgca cctacctcgc gtaccgcgac gcgggcggcg aggccatctg ggaggcgtag
     4141 cggtctcggc aggagcggcg gcgggcgcga acgcggcggt cgggatcggc acgcacgtcg
     4201 atcgatgaac ggcccgaatc gcgcctgccg gcgctcctac atgaaccctc cttccccaag
     4261 cgacgccgtg acgcccaccg cgggaacagc cgccacgaca cccgctgcgc catccgccgt
     4321 gacacgccct gtaggagcgg cggcagccgc gaagacggcg gtccggcaag cgcgtcgccc
     4381 attccgtgcg ccgcggttcg cgcctgccgg cgctcctaca tgaaccctcc tcctccaagc
     4441 gacgccacga cacccgccgc aacacccgac acgacatccg ccgcgacacg cgctgtagga
     4501 gcggcggcag ccgcgaagac ggcggtccgg cgagcgcgtc gcccattccg tgcgcggcgg
     4561 ttcgcgcctg ccggcgcccc tgcaggaacc ggacacgcaa agcgaaccgc ccacaccgcg
     4621 cggctgcacg gtgtgggcgg gaggcggtga caacccggaa gcggatcagc gcaggtcgaa
     4681 gcggtccgcg ttcatcacct tggtccacgc ggcgacgaag tcgcgcacga acttctcctg
     4741 gttgtcgtcc tgggcataca cctcggcata cgcgcgcagg atcgagttgg agccgaacac
     4801 cagatcgacg cgagtcgcgg tccacttctt cgcgccgctc ttgcgctcga cgatgtcgta
     4861 gctgttgcgc ccggtcggct tccagctgta gcgcatgtcg gtcagattca cgaagaagtc
     4921 gttggtcagg gcgccgacgc ggtcggtgaa cacgccgtgc ttgctgccgc cgtggttggt
     4981 gccgaggacc cgcaggccac cgatcagcac ggtcatctcg ggggcggtga ggccgagcag
     5041 ctgggcgcgg tcgagcagca tctcctcggg ctggaccacg taatccttct tctgccagtt
     5101 gcggaagccg tcatgcaccg gctccagcac ctcgaaggac tcgacgtcgg tctgcgcctg
     5161 gctggcatcg ccgcggcccg gggcgaaggg cacgtccaca ttgaagccgg ccgccttgat
     5221 cgcctgctcc aggccgacgt tgccgccgag cacgatcacg tcggcgacgc tggcgccagt
     5281 ctccgcggcg atcttctcgt aggccgcaag cgccctggcc aggcgtgccg gctcattgcc
     5341 ttcccagtcc ttctgcgggg cgaggcggat gcgcgcgccg ttggctccgc cgcggtagtc
     5401 cgagccgcgg aaggtgcggg cgctgtccca ggcggtggcg accatgtcgc ccaccgacag
     5461 gccggcggca gcgatcttcg ccttcaccgc ggcgacgtcg tagttcgtgt tgccggcggg
     5521 caccgggtcc tgccagatca ggtcttcagc aggcacgtcg ggaccgatgt agcgcgcctt
     5581 cggacccatg tcgcggtggg tgagcttgaa ccaggcgcgc gcgaagactt cctcgaaata
     5641 ggcttgatca ttgcggaagc gctccgcgat cttgcggtac tcggggtcga agcgcagcgc
     5701 catgtcggca tcggtcatca tcggcttgcg gcggatcgac gggtcttcca cgtccaccgg
     5761 catgtcttcc tcggcgatgt tcagcggctc ccactgccac gcaccggccg gcgacttctg
     5821 cagccaccag tcgtgcttga acagcatgtc gaagtagccg ttgtcccact gggtgggctt
     5881 ggaggtccac gcgccctcga tgccgctggt cacggtgtcg cgaccgacgc cgcgggtggt
     5941 gtggttcatc cagccgaagc cctgctcctc gaggtcggcg ccttcgggtg ccgggccgag
     6001 cagggcggcg ctgccgttgc cgtgcgcctt gccgacggtg tggccgccgg cggtgagcgc
     6061 cacggtctct tcatcgttca tcgccatgcg ggcgaaggtc acgcgcatgt cgtgggcggt
     6121 cttgagcggg tcgggcttgc cgtcgacgcc ctcggggttc acgtagatca ggcccatcat
     6181 caccgcagcg agggggttct cgaggtcgcg ctggccggag tagcgcgaac cctcgctgcc
     6241 gctgggggcc agccattcct tctcggagcc ccagtagatg tccttctcgg gatgccagat
     6301 gtcctcgcgg ccgaaggcga agccgaaggt cttgaagccc atcgactcgt aggccatgtt
     6361 gccggcgagg atgatgaggt cggcccagct gatcttgttg ccgtacttgc gcttgatcgg
     6421 ccacagcagg cggcgcgcct tgtcgaggtt gccgttgtcg ggccaggagt tcagcggcgc
     6481 gaagcgctgg ttgccggtgc ccgcgccgcc gcggccgtcg gcgatgcggt aggtgcccgc
     6541 ggcgtgccag gccatgcgga tcatcaggcc gccatagtgg ccccagtcgg ccggccacca
     6601 ttcctggctg tcggtcatca aggccttgag gtcgttcttg agtgcgtcga cgtcgagctt
     6661 cttcagctcc tcgcgatagt cgaagccggc gccgagcggg ttggtcttgc tgtcgtgctg
     6721 gtggaggatg tccaggttca gcgccttggg ccaccacgcc atcaccgagt ccttggaggc
     6781 ggtattgccg ccatgcatca ccgggcactt gccggcggtg ttcgtgctgt tctcgctcat
     6841 ctgattctcc ctctttgacg gtgacgcaaa ctatttgcga ggagcggtcg cacctcgcag
     6901 gaaagccctg ccacacctcg ccccgcgctc gcggaccagg gccggaagcg gtccaaaacc
     6961 gctgctgaca ggctcagact agcaaagatc ggatgctttt gaagcaatgg ggaggattga
     7021 tggaagctat cttccttggt tgcagtgcac aagaaaacct atccaaaggg cgtttgggaa
     7081 acgctttccc gtgcgactcc ccgagcgctc gcgtgccgcc caaggtccac gaaaaacgcc
     7141 ccgcgccgga gaggtcgcgg ggcgttttct cgggacgagg atgggctcag acccggcgtc
     7201 ggcgggccag ccccatgcct gcgagaccga gagcaatcag cgcaagcccc gcgggttcgg
     7261 gcaccggatt ggtcgagccg ttgtcggcac gctcgccggt gaaggccacc tcgccgatgg
     7321 agtaggagtt gtcgccatcc gtcgcctgga tccggacgta gcgcgcctcc cgcggcgtga
     7381 atgcgagctg tgacacgtac tcggaatcgg acggatcggt ggccatcgtg tccatccccc
     7441 aaccgatctc gcccacgcca ctcgacaccg tgagcaggct cgcccaggcg gagtagtcgg
     7501 tcgagtattc gagcaggtag ccgtcgttgt tatccaccga aagacggacg ctgtcgatgc
     7561 ggtacaggtc gccaaaggcg aacacgaagc gattgccctt gccgttccac gacaccttgt
     7621 cggccaggtt ccactggctg ccctcggtcg ggaagatccc gtcgttcagc acggagagcg
     7681 aaccgccata gttgccgcca ttgccgttgg cgctgacgac ggtagtgatc gaagccgcct
     7741 gagcggcagt ggcggagagc cccagcaagg tgaggacgag caatgtgcgt ttcatgtggc
     7801 gagccctggt gcgatcgaat gtatttatca aaagcaaggt ttgtgccaag agccatttcg
     7861 ccgacaacgg ctgagggtct cccgaacgcc cggatatcgc gtgtaaataa tcccgacacc
     7921 gtcaagcctc tttaagcctc gatctggggc gtaaacaccg ccatccccca agttggggtg
     7981 ctccctgcac aagaaatgtc gcaccctccc cccaaacgcc tcatgacgcc ccagattgag
     8041 tagttttttc tatgatcgac tgtaagaaat cccgacactc gccctccctt gcgccaccgg
     8101 cagcaccgac tgtcattttc ctgcaacccg gccgcaccac tcccgcagga aatgcgagaa
     8161 tcgcgcccca ccctggcagg cacgacctgt ccgacgggtc gaaagacaca acagacacca
     8221 tcgaggaaaa caacatgtcg aagaagttgg ctggtttgat cgttcttggg ctcgcgagcg
     8281 cgacgcccgc attcgccgcc ggacaggccg aggcgaaggg cttcgtggaa gacagcgcgc
     8341 tgaacgtgct gctgcgcaac gcgtacatca atcgcgatta caag
//
LOCUS       DAOTIN010000137         8290 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_10362_length_8290_cov_9.437644, whole genome shotgun sequence.
ACCESSION   DAOTIN010000137 DAOTIN010000000
VERSION     DAOTIN010000137.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 8290)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 8290)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8290
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_10362_length_8290_cov_9.437644"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..785)
                     /locus_tag="P5537_14685"
     CDS             complement(<1..785)
                     /locus_tag="P5537_14685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HRV79334.1"
                     /translation="MQHDSRKILGGLIATVLALNLFIAGLLGYAMLEAKSRKEHEVRT
                     TVENLALLLDQSVSSSVREIDLMLRGVQLRLERELREKGRLQRDDFDSAIVLHRDGLS
                     QTAQVRVSDSAGTVVLGDRVTSETRTSYADRPFFLDHRTLDDGETRASKLLHGRIANT
                     WIVVFSRRYNTPEGGFAGVVTAAVPADHFQRLLSGLQLGPHGIALVRDLDMTLVARWP
                     RLDAPAGVIGGRGGSLELSEIVASEVRAQSFYSARTADGVARI"
     gene            1039..2143
                     /gene="prfB"
                     /locus_tag="P5537_14690"
     CDS             join(1039..1119,1121..2143)
                     /gene="prfB"
                     /locus_tag="P5537_14690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011239085.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HRV79335.1"
                     /translation="MEAERQNAIAEKLADLAARGRELRRYLDYDVKASKLEEVNRALE
                     DPAVWNNAERAQELGKEKRQLEDVVLTLQEIDAQSRDLKDLFELAEAEDDDDTFEAVE
                     ADLVELQGAIEKLEFRRMFSNPMDPNNCFIEIQAGAGGTEAQDWAGMLERMYLRYGEK
                     KGFTVELMEETEGEVAGIKNCTIKFSGEYAYGYLRTETGIHRLVRKSPFDSNARRHTS
                     FTSVFVYPEVDDSIEIEINPADLRIDTYRASGAGGQHINKTDSAVRITHEPTGIVVQC
                     QNDRSQHKNKAEAMSMLKARLYEAELRKRQSEQQKLEDSKSDIGWGHQIRSYVLDQSR
                     IKDLRTNYEVGNTQAVLDGDLDDFIGASLKQGV"
     gene            2271..3542
                     /locus_tag="P5537_14695"
     CDS             2271..3542
                     /locus_tag="P5537_14695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79336.1"
                     /translation="MTDPFLSDFLAAGVDADEVPELAALNAARPLLDAFITLFRGTEA
                     EVLMRLLVLREIGREADAPRWAPEALRARFTYLDAVKLETVLKRLRDNGLLAIGEDGH
                     YALSDHGRNAVAAIAMLLRFGEEEDAELGFLTAQLAGLQAVGGITAESLGHLLSKLND
                     LTWHFEEAIASGSEFRILDARRRLSANGRWLERGTELLNRLLADPEVDFDIARIAQRI
                     GLAQSRLARADASFQRALNKIEAQRVTLGASGISSSDVAAWLRGLDAAAIATLAAEAC
                     ASVPELPLLAGGHELLDRAEALLEGGGTATAADTTLPPADEAATGFAPQAEDLRLLEH
                     FTHRLEALPAPQPLHRIIAGGGFAPASYRLSLLALLADGAESGPEEGPVGSFMRLPLE
                     VEFGDTLTAVGEDEIAAMTLGEVRPRAAAPA"
     gene            3558..4268
                     /locus_tag="P5537_14700"
     CDS             3558..4268
                     /locus_tag="P5537_14700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79337.1"
                     /translation="MEHELKTLTARLLAQRWLPRSDRLVRRALVDETFRLELDRRLAD
                     VGLRLLDNPYAAHVGVALQPELAEPVFGAGREYAASNLGLTRDEIALLVILWALIVLP
                     KRERQVTRRELVDDGQTDLFGGDKPVAHGDAVSGTLTEASLIADFGPRLGGRTKVRNF
                     MLGKLARLGFIERRNGLITEGPLLDLALDYRVMADRIIHGTLGEILDAAGHPPPAHNA
                     FELAEVLPDEAEALDEEG"
     gene            4273..5379
                     /gene="trmA"
                     /locus_tag="P5537_14705"
     CDS             4273..5379
                     /gene="trmA"
                     /locus_tag="P5537_14705"
                     /EC_number="2.1.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030697 - S-adenosylmethionine-dependent
                     tRNA (m5U54) methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (uridine(54)-C5)-methyltransferase TrmA"
                     /protein_id="HRV79338.1"
                     /translation="MPLPHIDPARYEDQLAAKLDRYRADFAEFDLPEPAVFRSAPLHY
                     RLRAEFRLWHHEGRIDYAMFDSADPKQPILLETFPAAAEPIATLMPRLRDALQASEPL
                     RRKIFQVEFLATLSGECLVSLVYHRPLDEAWEAAARTLAADLQIQLIGRSRKQKIVLD
                     RDWVQEVLEVDGLALRYQQFEGSFTQPNGGVNQHMLGWARAQAKAVGTRPQVPGDLLE
                     LYCGNGNFTVALAPLFGRVLATEMSKTSVRAANTNLADNNVANVTMVRMASEEISDAL
                     AGGREYRRMAGVDLAGYRFSTLFVDPPRAGLDEGTIALARGFDHILYISCNPETLRAN
                     VAALAATHRIAAAAAFDQFPYTHHLECGLLLQRR"
     gene            5401..8193
                     /locus_tag="P5537_14710"
     CDS             5401..8193
                     /locus_tag="P5537_14710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HRV79339.1"
                     /translation="MFHIKTLELVHWDFWRRFALPLDAQIITIVGPNGSGKTTLLDAL
                     RTLFALRCSGKRDFRRYVRRADRSFAWIRAVVANLPGHTGKRPFFPCLADEVTLACRI
                     RKAGGDWIRDYTIVDGNLPIETLESSNDWIGLRDYQHRLAWGGLTPAITKVLALEQGD
                     TDKLCEYSPKALLELVFDVFGDKEVLDNYQAAREEQKSAERELGELGIDLDRLKTQAE
                     EKKAEANRFLEWKQLADEIHALEAEIVPRLEVAELERELAAEREALCRVGQERADKLV
                     EQRESRQRLEIVRAEQEAAQAERKRLKDDDRASEQRYLAAHDRVRDLDRLLEERDMLR
                     AQLASEHGADAVALEKEHEEADAALAALRRKERELVAAFEERGETLRGERNRAGAPGD
                     AEVARFRVRLSAEGIAHCSLAEVVEVTDPAWQAALEAILRPYRYLILLERETDRHAAW
                     ALGERERFRHFIVAERESAPPPRPMSLAEVVEFGAPVPRWLADLLNRIRRVEDAHAAR
                     DLPREQEWITRDGYHRERRGARHLGRPQEFHFGELARQSRIAALQDEIGGLDRQLQAL
                     RPKLDAASARLTTLRQRLLGLQSAQLLAARAEAYASAEAELSAARKTLTEAIAERTET
                     RGEIDRLADKLNGIQIELDRRNRELKAVELRLADIAREHGPRRRAQAERILALRRRRR
                     GMPGHWLDAGELALLAEKYGDARGARLQLERLRRHLDEGEWITDPAVVVVRDRLAADV
                     ALRERDYLNRQGYCTTARLHTDNARAAYIAKLRATVRQYARNLKALGELANLSVDCPT
                     PHLDNDDLSLAQAGLEVRFDFDRKGAVGLNDGEASGGQQVMKSLILLIGLLMDESRPG
                     GFVFIDEPFAHLDVANIDRVGTFLRATRAQYLITTPVTHNANVFAPAQLTLVTRKKPP
                     GTDWAPPIGVLQRAVD"
BASE COUNT         1330 a         3169 c         2701 g         1090 t
ORIGIN      
        1 ttgatccgcg ccacgccatc ggccgttcgg gcgctgtaga aggactgcgc gcggacctcg
       61 gaggcaacga tctcgctcag ctcgagggag ccgccgcgcc cgccgatcac cccggcaggg
      121 gcatcgaggc gcggccagcg cgcaaccagc gtcatgtcga ggtcccgcac cagggcgata
      181 ccgtgtggcc cgagttgcag gcccgagagc aggcgctgga agtgatctgc cggcacggct
      241 gcggtgacga cgccggcgaa gccgccctcg ggcgtgttgt agcggcgcga gaacacgacg
      301 atccaggtgt tggcgatgcg cccgtgcagc agcttgctcg cccgggtctc gccatcgtcc
      361 agcgtacgat gatcgagaaa gaacggacgg tctgcataac tcgtccgcgt ctcggacgtg
      421 acccggtcgc cgagcacaac ggttcccgcg gagtcgctca cgcgcacctg ggccgtctgc
      481 gacagcccgt cacgatgcag gacgatcgcc gaatcgaaat cgtcgcgctg cagccgcccc
      541 ttttcgcgca actcgcgctc gagccgaagc tggaccccgc gcagcatcag atcgatctcg
      601 cgcaccgagg agctgacgct ctggtcgagc agcagggcca ggttctcgac cgtggtgcgc
      661 acctcgtgtt ccttgcggga cttcgcctcc agcatcgcat agcccagcag tcccgcgatg
      721 aacaggttga gcgccagcac cgtggcgatc agtcccccga ggatcttcct gctgtcgtgc
      781 tgcatgtgtc cgcctgacga tttccttgag cattcgccga gttgatgacg gcatgccgcc
      841 ccgtatcggg gcgtaattgt aatcgccccg cctgcggatg ctccatcccg ggcaccatct
      901 acgcgcggcg agccccgcag cttcgcggcg gagacgaagc ccttggcgat gaagtgcgct
      961 gtcgatgaag ctcgcctgca gcggacggct tcgcggcggt ataatgcgcg gttttccaga
     1021 ttccgccgga gcctcgccat ggaagccgaa cgccagaacg ccatcgccga aaaactcgcc
     1081 gacctcgccg cccgcggtcg cgaactacgg aggtatcttt gactacgatg tgaaggcatc
     1141 gaagctcgaa gaggtcaacc gcgcgctcga ggacccagcc gtctggaaca acgccgagcg
     1201 cgcgcaggag ctcggcaagg agaagcgtca gctcgaggac gtggtgctga cgctgcaaga
     1261 gatcgacgcg cagtcgcgcg acctcaagga tctcttcgaa ctcgccgagg ccgaggacga
     1321 cgacgacacc ttcgaggcgg tcgaggccga cctcgtcgag ttgcagggcg cgatcgagaa
     1381 gctcgagttc cgccgcatgt tcagcaaccc gatggacccc aacaactgct tcatcgagat
     1441 ccaggccggc gccggcggca ccgaggcgca ggactgggcg ggcatgctcg agcgcatgta
     1501 cctgcgctac ggcgaaaaaa agggcttcac cgtcgagctg atggaagaga ccgagggcga
     1561 ggtcgcgggc atcaagaact gcacgatcaa gttctccggc gaatacgcct acggctacct
     1621 gcgcaccgag accggtatcc accgcctggt gcgcaagtcg ccgttcgact ccaacgcgcg
     1681 ccgccacacc agctttacct cggtgttcgt gtatcccgag gtcgacgact cgatcgagat
     1741 cgagatcaac cccgccgacc tgcgcatcga cacctaccgc gcctccggcg ccggcggcca
     1801 gcacatcaac aagaccgact ccgcggtgcg catcacccac gagcccaccg gcatcgtcgt
     1861 gcagtgccag aacgaccgct cgcagcacaa gaacaaggcc gaggccatgt cgatgctgaa
     1921 ggcgcgcctg tacgaggccg agctgcgcaa gcgccagtcc gagcagcaga agctggaaga
     1981 ctccaagagc gacatcggct ggggtcacca gatccgcagc tacgtgctcg accagtcgcg
     2041 catcaaggac ctgcgcacca actacgaggt cggcaacacc caggccgtgc tcgacggcga
     2101 cctcgacgac ttcatcggcg ccagcctcaa gcagggcgtc tgagctcgct accgaccggc
     2161 attgagccca cgttcgcggg caagcccact cccacggcga tcgctgcggc cttgtgggag
     2221 cgggcttgtc cgcgaaactg ccgatcggcg cctgcaagat ccgatgatcg atgactgatc
     2281 ccttcctctc cgacttcctc gccgcgggcg tggacgccga cgaagtgccc gagctcgcgg
     2341 cgctgaacgc cgcgcgcccg ctgctcgacg ccttcatcac gctgttccgc ggcaccgagg
     2401 ccgaggtgct gatgcgcctg ctggtgctgc gcgagatcgg ccgcgaggcc gacgcgccgc
     2461 gctgggcgcc cgaggcgctg cgcgcgcgct tcacctacct cgacgcggtc aagctcgaga
     2521 cggtgttgaa gcgcctgcgc gacaacggcc tgctcgccat cggcgaggac ggccactacg
     2581 cgctctccga ccacggccgc aacgcggtgg cggcaatcgc gatgctgctg cgcttcggcg
     2641 aggaggagga cgccgagctc ggcttcctca ccgcccagct cgccggcctg caggcggtgg
     2701 gcggcatcac cgccgagtcg ctcggccacc tgctctccaa gctcaacgac ctcacctggc
     2761 acttcgagga ggcgatcgcc tccggctccg agttccgcat cctcgacgcc cgccgtcgcc
     2821 tgtcggccaa tgggcgctgg ctggagcgcg gcaccgagct cctcaacagg ctgctcgccg
     2881 accccgaggt cgacttcgac atcgcccgca tcgcgcagcg catcggcctg gcgcagtcgc
     2941 gcctggcgcg cgccgacgcc tccttccagc gcgcgctcaa caagatcgag gcgcagcgcg
     3001 tgacgctggg cgcctcgggc atctcgtcct cggacgtcgc cgcctggctg cgcgggctcg
     3061 acgcggccgc gatcgccacg cttgcggccg aggcctgcgc gagcgtgccc gagctgccgc
     3121 tgctcgctgg cgggcacgag ctgctcgacc gcgcagaggc cttgctcgaa ggcggcggca
     3181 ccgccaccgc ggccgacacc accctacccc cggccgacga ggccgcgacc ggcttcgccc
     3241 cccaggccga ggatctgcgc ctgctcgaac acttcaccca ccgcctcgag gccctgcccg
     3301 cgccgcaacc gctgcaccgc atcatcgcgg gcggcggctt cgcaccggcg agctaccgcc
     3361 tgtcgctgct cgccctgctc gccgacggcg ccgagagcgg tcccgaggag ggccccgtgg
     3421 gcagcttcat gcgcctgccg ctggaggtcg agttcggcga cacgctgacc gcggtcggcg
     3481 aggacgagat cgccgcgatg acgctcggcg aggtgcgccc gcgcgccgcc gccccggcct
     3541 gagccaccag gatttccatg gaacacgaac tcaagaccct caccgcgcgc ctgctcgcgc
     3601 agcgctggct gccgcgcagc gaccgcctgg tgcggcgcgc gctggtggac gagaccttcc
     3661 gcctcgagct cgaccggcgc ctggccgacg tcggcctgcg cctgctcgac aacccctacg
     3721 ccgcccacgt cggcgtcgcg ctgcagcccg agctggccga gccggtgttc ggcgccgggc
     3781 gcgagtacgc cgccagcaac ctgggcctga cccgcgacga gatcgcgctg ctggtcatcc
     3841 tctgggcgct gatcgtgctg cccaagcgcg agcgccaggt cacccggcgc gagctggtcg
     3901 acgacggtca gaccgacctc ttcggcggcg acaagccagt ggcgcacggc gacgcggtct
     3961 cgggcacgct caccgaggcc tcgctgatcg ccgacttcgg cccgcgcctg ggtggccgca
     4021 ccaaggtgcg caacttcatg ctcggcaagc tcgcccgcct cggcttcatc gagcgccgca
     4081 acggcctcat caccgagggc ccgctgctcg acctcgccct cgactaccgc gtgatggccg
     4141 accgcatcat ccacggcacc ctgggcgaga tcctcgacgc cgccggccac ccgccgcccg
     4201 cgcacaacgc cttcgagctc gccgaggtcc tgcccgacga ggccgaagcc ctcgacgagg
     4261 aaggctgaac ccatgcccct gccccacatc gaccccgcgc gctacgagga ccagctcgcc
     4321 gccaagctcg accgctaccg cgccgacttc gccgagttcg acttgcccga gcccgcggtc
     4381 ttccgctccg ccccgctgca ctaccgcctg cgtgccgagt tccgcctgtg gcaccacgag
     4441 ggccgcatcg actacgcgat gttcgacagc gccgatccga agcagcccat cctgctcgag
     4501 accttccccg ccgccgccga acccatcgcc accctgatgc cgcggctgcg cgacgcgctc
     4561 caggcgagcg agccgctgcg gcgcaagatc ttccaggtcg agttcctcgc caccctgagc
     4621 ggcgagtgcc tggtgagcct ggtctaccac cgcccgctcg acgaggcctg ggaggccgcc
     4681 gcgcgcacgc tcgccgccga cctgcagatc cagctcatcg gccgcagccg caagcagaag
     4741 atcgtgctcg atcgcgactg ggtgcaggag gtgctcgagg tcgatggtct ggccctgcgc
     4801 taccagcagt tcgagggcag cttcacccag cccaatggcg gcgtgaacca gcacatgctg
     4861 gggtgggcgc gcgcgcaggc gaaggccgtg ggcacgcgcc cgcaagtccc gggcgacctg
     4921 ctcgagctct actgcggcaa cggcaacttc accgtcgcgc tggcgccgct gttcggccgc
     4981 gtgctcgcca ccgagatgag caagacctcg gtgcgcgcgg cgaacaccaa cctcgccgac
     5041 aacaatgtag ccaacgtgac catggtgcgc atggcgagcg aggagatcag cgacgcgctc
     5101 gccggcgggc gcgagtaccg ccgcatggcg ggcgtggacc tggccggcta ccgcttctcc
     5161 acgctcttcg tcgatccgcc gcgcgccggc ctcgacgagg gcacgatcgc gctggcgagg
     5221 ggtttcgacc acatcctcta catctcctgc aacccggaga ccctgcgcgc caacgtcgcc
     5281 gcgctcgccg ccacccaccg catcgccgcc gccgcagcct tcgaccagtt cccctacacc
     5341 caccacctcg agtgcgggct gctgctgcag cggcgctgaa cctcaccgcg accccggccc
     5401 atgttccaca tcaagaccct cgagctcgtc cactgggact tctggcggcg cttcgcgctg
     5461 ccgctggacg cgcagatcat caccatcgtc ggccccaacg gctcgggcaa gaccacgctg
     5521 ctcgacgctc tgcgcacgct gttcgcgctg cgctgctcgg gcaagcgcga cttccgccgc
     5581 tacgtgcgcc gcgccgaccg cagcttcgcg tggatccgcg cggtggtcgc caacctgccc
     5641 ggccacaccg gcaagcggcc cttcttcccc tgcctggccg acgaggtcac cctcgcctgc
     5701 cgcatccgca aggccggcgg cgactggatc cgcgactaca ccatcgtcga cggcaacctg
     5761 ccgatcgaga cgctggagag ctccaacgac tggatcggcc tgcgcgacta ccagcaccgc
     5821 ctggcctggg gcggcctgac cccggcgatc accaaggtgc tagcgctcga gcagggcgac
     5881 accgacaagc tgtgcgaata ctcccccaag gcgctgctcg agctggtctt cgacgtcttc
     5941 ggcgacaagg aggtgctgga caactaccag gccgcgcgcg aggagcagaa gtccgccgaa
     6001 cgcgagctcg gggagctcgg catcgacctc gaccgcctca agacccaggc cgaggagaag
     6061 aaggccgagg ccaaccgctt cctggagtgg aagcagctcg ccgacgagat ccacgcgctg
     6121 gaagcggaga tcgtgccgcg cctggaggtc gccgagctcg agcgcgagct cgccgccgag
     6181 cgcgaggccc tctgccgcgt cggccaagag cgcgccgaca agctcgtcga gcagcgcgag
     6241 tcgcgccagc gcctggagat cgtgcgcgcc gagcaggagg ccgcgcaggc cgagcgcaag
     6301 cgcctgaagg atgacgaccg cgcttccgag cagcgctacc tcgccgccca cgaccgcgtg
     6361 cgcgacctcg acaggctgct cgaagagcgc gacatgctgc gcgcccagct cgccagcgag
     6421 cacggcgccg acgccgtggc gctggagaag gagcacgagg aggccgacgc cgcgctcgcc
     6481 gcgctgcgcc gcaaggagcg cgagctggtc gccgccttcg aggagcgcgg cgagaccctg
     6541 cgcggcgagc gcaaccgcgc cggcgcgccg ggcgacgccg aggtcgcgcg cttccgcgtc
     6601 aggctgagcg ccgaaggcat cgcgcactgc agcctggccg aggtggtgga ggtcaccgac
     6661 cccgcctggc aggccgcgct cgaggccatc ctgcgcccct accgctacct gatcctgctc
     6721 gagcgcgaaa ccgaccgcca cgccgcctgg gcgctcggcg agcgcgagcg cttccgccac
     6781 ttcatcgtgg ccgagcgcga atccgccccg ccgccgcgtc cgatgagcct ggccgaggtg
     6841 gtggagttcg gcgcgccggt gccgcgctgg cttgccgacc tgctcaaccg catccgccgc
     6901 gtcgaggacg cccacgccgc gcgcgatctg ccgcgcgagc aggagtggat cacccgcgac
     6961 ggctaccacc gcgagcgccg cggcgcccgc cacctcggcc ggccgcagga gttccacttc
     7021 ggcgagctcg cccgccagtc gcgcatcgcc gcactgcagg acgagatcgg cgggctcgac
     7081 aggcagctcc aggccctgcg ccccaagctc gacgccgcca gcgcccgcct caccacgctg
     7141 cgccagcgcc tgctcggcct gcagtcggcg cagctgctcg ccgcccgcgc cgaggcctac
     7201 gccagcgccg aagccgagct gtctgccgcg cgcaagacgc tcaccgaggc gatcgccgaa
     7261 cgcaccgaga cgcgcggcga gatcgaccgc ctcgccgaca agctgaacgg catccagatc
     7321 gagctcgacc gccgcaaccg cgagctcaag gccgtcgagc tgcgcctggc agacatcgcg
     7381 cgcgagcacg gcccgcgccg ccgcgcccag gccgagcgca tcctcgccct gcgccggcga
     7441 cggcgcggca tgccggggca ctggctggac gccggcgagc tcgcgctgct cgccgagaaa
     7501 tacggcgacg cgcgcggcgc ccgcctgcag ctcgagcgcc tgcgccgcca cctcgacgag
     7561 ggcgagtgga tcaccgatcc cgcggtggtg gtggttcgcg accgcctcgc cgccgacgtc
     7621 gcattgcgcg agcgcgacta cctcaaccgc cagggctact gcaccaccgc acgcctgcac
     7681 accgacaacg cccgcgccgc ctacatcgcc aagctgcgcg ccactgtgcg ccagtacgcc
     7741 aggaacctga aggcgctcgg cgagctcgcc aacctcagcg tggactgccc caccccgcac
     7801 ctcgacaacg acgacctctc gctcgcccag gccgggctcg aggtgcgctt cgacttcgac
     7861 cgcaagggcg cggtgggcct caacgacggc gaggcctcgg gcggccagca ggtcatgaag
     7921 tcgctgatcc tcttgatcgg cctgctgatg gacgagtccc gcccgggcgg cttcgtgttc
     7981 atcgacgagc ccttcgccca cctggacgtc gccaacatcg accgcgtcgg caccttcctg
     8041 cgcgccaccc gcgcgcagta cctgatcacc accccggtca cccacaacgc caacgtcttc
     8101 gcgcccgcgc agctcacgct ggtgacgcgc aagaagccgc ccggcaccga ctgggcgccg
     8161 ccgatcggcg tactgcaacg ggcggtggac tgacgcgcaa ggccgtcgca agcacccagc
     8221 ccccccagca gcccgggagc cgcgatgttt catgtaggag cgccggcagg cgcgaaagcg
     8281 gcgcgtggga
//
LOCUS       DAOTIN010000138         8285 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_10373_length_8285_cov_8.896112, whole genome shotgun sequence.
ACCESSION   DAOTIN010000138 DAOTIN010000000
VERSION     DAOTIN010000138.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 8285)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 8285)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8285
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_10373_length_8285_cov_8.896112"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..443)
                     /locus_tag="P5537_14715"
     CDS             complement(<1..443)
                     /locus_tag="P5537_14715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF484 family protein"
                     /protein_id="HRV79340.1"
                     /translation="MNAEDVARYLREHPDFLNQHHELFSELTVPHPQHGGQAISLAER
                     QLHALRDKIRALELKLAELIRFGEENDDISTKVHRLSVVLLQAGSAAVVRQGLVDSLR
                     DDFAVPYVSLKLWGEAAGGVVHSEAFGVGEAARRQVENLRHPWCGA"
     gene            complement(580..1413)
                     /gene="dapF"
                     /locus_tag="P5537_14720"
     CDS             complement(580..1413)
                     /gene="dapF"
                     /locus_tag="P5537_14720"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004315755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HRV79341.1"
                     /translation="MKLRFTKMHGLGNDFVVIDATRAPVDLTPARVKAIADRHFGVGC
                     DQLLVVEPAGGADVDFRYRIFNADGGEVEQCGNGARCFVRFVHDRGLTDKAEIRVETR
                     SGIIAPRLRADGLVTVDMGVPELAPVKVPFVSDSDAVVQPLQVGPDTVAITVVSMGNP
                     HAVQVVADVDAAPVRDQGAAIERHARFPARVNAGFLQVVDAHEVRLRVFERGAGETLA
                     CGTGACAAVVAGILRGLLETPVRVHTRGGELEIAWDGPGTPVRMTGPAVTVFEGEMEL
                     A"
     gene            complement(1431..>1985)
                     /locus_tag="P5537_14725"
     CDS             complement(1431..>1985)
                     /locus_tag="P5537_14725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HRV79342.1"
                     /translation="RPVLLLAPHFLGLDMAGTRLTLEGDFVSVYSPQKDKVFDHWLHH
                     GRSRFNDQLLLSRHDGVRATVKAMKSGRPFYYLPDLDYGRKESIFVPFFGVPAATITG
                     LPRLARLANAAVVPCVVRMLPGGGGYVLELGAPWADYPSDDVEADTLRMNAWLEGVIR
                     TMPEQYYWVHRRFKTRPEGEPRIY"
     assembly_gap    1986..2085
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<2086..2927)
                     /locus_tag="P5537_14730"
     CDS             complement(<2086..2927)
                     /locus_tag="P5537_14730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HRV79343.1"
                     /translation="MLSQRAFRLLSRLPLSWLHRLGGWAGWLTYKSSPSYARRLRENL
                     FNALGREDEAVLRAAVVEAGRQALELPFIWGRPAAEVVASAVRTEGWELVEAARAEGA
                     GILFITPHLGCFEITAQCIAAKIPITVLYRPPRKEVLQPLMEAGRARGQMRTAPADLS
                     GVRKLVKTLRSHEAVGMLPDQVPGAGEGVWAPFFGKPAWTMTLAARLAAVKGVRVIYT
                     WAERLPRGEGYVFRLQAPTEPLSGDLDTDVAIINREVERMILQCPQQYLWGYNRYKGP
                     RRER"
     gene            3175..4338
                     /gene="metK"
                     /locus_tag="P5537_14735"
     CDS             3175..4338
                     /gene="metK"
                     /locus_tag="P5537_14735"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004315758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HRV79344.1"
                     /translation="MAEFLFTSESVSEGHPDKVADQVSDGVLDAILAEDPKARVACET
                     LVSTGLVVISGEITTTAHPNYREIAQDVIRRIGYDNSDIGFDYKSCAVLAAINRQSPD
                     IAQGVDNANDDPLDQGAGDQGLMFGYATNETASLMPLPIHYAHRVMQRQAEVRKDGRL
                     PWLRPDAKSQLTVRYVDGKPVAIDTEVVSTQHDPDVTQEQIREAVIELIIKPVLPPEL
                     MKGDVRYLVNPTGRFVVGGPHGDCGLTGRKIIVDTYGGAAHHGGGAFSGKDPSKVDRS
                     AAYAGRYVAKNVVAAGLADRCEVQVAYAIGVARPVSLMVNTFGTGRIADDKIVELIGR
                     HFDLRPKAIIQTLDLLRPVYSRTAAYGHFGRDEPGFTWEQTDKAAALRADAGL"
     gene            4351..5430
                     /locus_tag="P5537_14740"
     CDS             4351..5430
                     /locus_tag="P5537_14740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0098662 - inorganic cation transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HRV79345.1"
                     /translation="MLQQVLMFAAGLAVLVVGADVLVRGASRLAVSFGVSPLVVGLTV
                     VAFGTSAPEMAVSVGSALAGSPDLAIGNVVGSNIANVLLILGISALITPLLVDEQIIR
                     QEIPIMIGASALLVVMALDGNIGLLESIALFGLVIAYTVFLVVQSRRASKAVQDEFET
                     EIPTSTWDRHWAVQVGLIVGGLVMLVVGADWLVDSAVAFARAFGVSDLVIGLTVVAVG
                     TSMPEIATSIVAAIRGQRDIAVGNVVGSNVFNLLAVLGAAGIASGAGLPVSEAARNFD
                     LWVMLAVAFACLPIMITGREIARWEGGVFLAYYAAYTAWLVLQAQQHASLPAFSGIML
                     GYVLPLTVITLVVSLVRQQGKKRAG"
     gene            complement(5458..7092)
                     /locus_tag="P5537_14745"
     CDS             complement(5458..7092)
                     /locus_tag="P5537_14745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HRV79346.1"
                     /translation="MSSRTLTVRAQLILLAAVSCTLFAIALAVAVWQLQAGGARLSAF
                     IDTELAAEREATRAYAHGLQMGQALRNILLDPANPKAYENFQAAKTGFDDTLARLLAA
                     PAVLDGGVATAARLRELAERWAPLQAQVIERVRAGDNVAAQRTLVASETPAWREVRAE
                     LMKQVAHLEKLAGATRASSAAAIERGRLTVSALGGAALLACLVASVLVVRGVLGQLGG
                     EPAVVAAVARRMTEGDLQQNITAAAARPDSLMVAMQAMQSGLGGIVREIRGDAVRVVE
                     AAAGLRHNEEEVASAALAQSDGAQSIAAAVEEMSASIAVVAELADDADRFSGEAEQRV
                     RDGGAVINEAVDMIGRVSERMSASAAVVGDLGARAESISDIAKVIQGIAEQTNLLALN
                     AAIEAARAGEQGRGFAVVADEVRKLAERTAQSTQEINTMIERVQDSARQAVDTMEDGR
                     ELAGRGAACAARAHEAVGALEEGTVRVRQVVGEISLALREQRETSTSIAQSVERIARM
                     SERSHTATRDSLQRAQALDGLADGLARAVGRFRVAG"
     regulatory      7290..7393
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01057"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="S-adenosyl-L-homocysteine riboswitch; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosyl-L-homocysteine"
                     /db_xref="RFAM:RF01057"
     gene            7508..>8285
                     /locus_tag="P5537_14750"
     CDS             7508..>8285
                     /locus_tag="P5537_14750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004367406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylhomocysteinase"
                     /protein_id="HRV79347.1"
                     /translation="MNAVADTKFTDFVVADLALAAWGRKEIRIAETEMPGLMAIREEY
                     AASQPLKGARITGSLHMTIQTAVLIETLTALGAQVRWASCNIFSTQDHAAAAIAADGI
                     PVFAVKGESLTDYWNYTHRIFEWPDGGYSNMILDDGGDATLLLHLGARAEQDLSVLAK
                     PGSEEETILFAAIRAKLAQDPTWYSTRLAQVKGVTEETTTGVHRLYQMHARGELKFPA
                     INVNDSVTKSKFDNLYGCRESLVDGIKRATDVMVAGKIAVV"
BASE COUNT         1223 a         2984 c         2774 g         1204 t
ORIGIN      
        1 gccccgcacc aggggtggcg caggttctcg acctggcgac gcgccgcctc gccgacgccg
       61 aaggcctcgg agtgcaccac cccgcccgcg gcctcgcccc aaagcttgag gctgacgtac
      121 gggacggcga agtcgtcgcg caggctgtcg accaggccct ggcgcaccac ggcggccgag
      181 cccgcctgca acagcacgac cgacaggcgg tgcaccttgg tgctgatgtc gtcgttctcc
      241 tcgccgaagc ggatcagctc ggcgagcttg agctcgagcg cgcgaatctt gtcgcgcagc
      301 gcatgcagct ggcgctcggc gagcgagatc gcctggccgc catgctgcgg gtgcggcacg
      361 gtgagctcgc tgaagagctc atgatgctgg ttgaggaaat cggggtgttc gcgcaggtag
      421 cgcgcgacgt cttcggcgtt catcgatgct tctccagacg gggcgccgag cgccccgcgt
      481 cgatcgttcg tggatggccg ccgcatccgg cggtcggccg caagcgggcc agcacgatgc
      541 cgcacaggcg catcgcgtcc ggcccggcga gatccgggct caggcgagct ccatctcgcc
      601 ctcgaaaacc gtcaccgccg gcccggtcat gcgcaccggc gtgcccgggc cgtcccaggc
      661 gatctccagt tcgccgccgc gggtgtgcac ccgcaccggc gtctccagca ggccgcgcag
      721 gatccccgcg accaccgccg cgcaggcgcc ggtgccgcag gccagggtct cgccagcgcc
      781 gcgctcgaac acgcgcaggc gcacctcgtg cgcatcgacc acctgcagga agccggcatt
      841 gacccgcgcc gggaagcgcg cgtggcgctc gatcgccgcg ccctggtcgc ggaccggcgc
      901 ggcatcgacg tcggccacga cctgcaccgc gtgcgggttg cccatcgaca ccacggtgat
      961 cgccaccgtg tcgggaccca cctgcagcgg ctgcaccacc gcatccgagt cggacacgaa
     1021 gggcaccttc accggtgcca gttccggcac gcccatgtcc accgtgacca gcccgtccgc
     1081 gcgcagccgc ggcgcgatga tcccggagcg cgtctcgacg cggatctcgg ccttgtcggt
     1141 gagccccctg tcatgcacga agcgcacgaa gcagcgcgcg ccgttgccgc actgctcgac
     1201 ctcgccgcca tcggcgttga aaatgcggta gcggaaatcg acgtccgcgc cgccggccgg
     1261 ctcgactacc agcaactggt cgcagccgac accgaagtgg cggtcggcga tcgccttgac
     1321 gcgcgccggc gtcaggtcga ccggcgcacg cgtggcgtcg atgacgacga agtcgttgcc
     1381 caggccgtgc atcttggtga agcgcagttt catcttgctg ttccagagtt tcagtagatc
     1441 cgcggctcgc cctcggggcg ggtcttgaag cggcggtgca cccagtagta ctgctcgggc
     1501 atggtgcgga tcacgccctc cagccaggcg ttcatgcgca gggtgtcggc ctcgacgtcg
     1561 tccgaggggt aatccgccca gggcgcgccg agctccagca catagccgcc gcctccgggc
     1621 agcatgcgca ccacgcaggg cacgaccgcc gcgttggcca gccgcgccag ccgcggcagg
     1681 ccggtgatgg tggccgccgg cacgccgaag aagggcacga agatcgactc cttgcggcca
     1741 tagtcgagat cgggcaggta gtagaagggg cggccggact tcatcgcctt gacggtggcg
     1801 cgcacgccgt cgtggcgcga cagcagcagc tggtcgttga agcggctgcg gccgtggtgc
     1861 agccagtggt cgaagacctt gtccttctgc ggcgaataca cgctgacgaa gtcgccctcg
     1921 agcgtgagcc gggtgccggc catgtcgagg ccgaggaagt gcggcgccag cagcagcacc
     1981 gggcgnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnntcgcg ctcgcgccgc
     2101 ggccccttgt agcggttgta gccccacagg tactgctgcg ggcactgcag gatcatgcgt
     2161 tcgacctcgc ggttgatgat cgccacgtcg gtgtcgaggt cgccgctgag cggttcggtg
     2221 ggggcctgca ggcggaacac gtagccctcg ccgcgcggca ggcgctcggc ccaggtgtag
     2281 atcacgcgca cgcccttcac cgccgccagg cgcgcggcca gcgtcatggt ccacgccggc
     2341 ttgccgaaga agggcgccca cacgccctcg cccgcgcccg gcacctggtc gggcagcatg
     2401 cccaccgcct cgtggctgcg cagggtcttg accagcttgc gcacgccgga caggtcggcc
     2461 ggcgcggtgc gcatctgccc gcgcgcgcgg ccggcctcca tcagcggctg cagcacctcc
     2521 ttgcgcggcg ggcgatagag cacagtgatc ggaatcttcg ccgcgatgca ctgcgcggtg
     2581 atctcgaagc agcccagatg cggggtgatg aagaggatgc ccgcgccctc ggcgcgcgcc
     2641 gcctcgacca gttcccagcc ctcggtgcgc accgcgctcg ccaccacctc ggccgccggc
     2701 cgcccccaga tgaagggcag ctcgagcgcc tggcggccgg cctcgacgac ggccgcgcgc
     2761 agcaccgcct cgtcctcgcg accgagcgcg ttgaagaggt tctcgcgcag gcggcgggca
     2821 taggacggcg aactcttgta ggtcagccag cccgcccagc caccgaggcg gtgcagccag
     2881 gaaaggggca ggcgggagag gaggcgaaat gcgcgttgcg acagcaccag ggggagatcc
     2941 gatatggatg ccggaaccgg cttcagtccc gaatgcttac acagccgcgc gtcccggtct
     3001 ataatcgcgg ctccaccgcc gagttaactc gacaacttgc agggcggtgg gacggccgcg
     3061 gcgccgtccg aaccaagtac tgctaaagcg tcggctgctc gacgaaatcc ccggagctgg
     3121 ccgcagacgc aaggccatcg caacggggat ttttgtcttt cagggagcag taccatggct
     3181 gaatttctct tcacctccga atcggtctcc gaaggccatc ccgacaaggt cgcggaccag
     3241 gtctccgacg gcgtgctcga tgccatcctg gccgaagacc ccaaggcgcg cgtcgcctgc
     3301 gagaccctgg tctcgaccgg cctcgtggtg atctcgggcg agatcaccac caccgcccac
     3361 cccaactacc gcgagatcgc gcaggacgtc atccgccgca tcggctacga caactccgac
     3421 atcggcttcg actacaagag ctgcgccgtg ctggcggcga tcaaccgcca gtcgcccgac
     3481 atcgcccagg gcgtggataa cgccaacgac gacccgctcg accagggcgc cggcgaccag
     3541 ggcctgatgt tcggctacgc caccaacgag accgccagcc tgatgccgct gccgatccac
     3601 tacgcccacc gcgtcatgca gcgccaggcc gaagtgcgca aggacggccg cctgccgtgg
     3661 ctgcgcccgg acgccaagag ccagctcacg gtcaggtacg tcgacggcaa gccggtggcg
     3721 atcgacaccg aggtggtgtc cacccagcac gaccccgacg tgacccagga gcagatccgc
     3781 gaggcggtga tcgagctgat catcaagccg gtgctgccgc ccgagctgat gaagggcgac
     3841 gttcgctacc tggtcaaccc caccggccgc ttcgtggtcg gcggcccgca cggcgactgc
     3901 ggcctcaccg ggcgcaagat catcgtcgac acctacggcg gcgcagccca ccacggcggc
     3961 ggtgcgttct cgggcaagga cccgtccaag gtcgaccgct cggctgccta cgctggccgc
     4021 tacgtggcca agaacgtggt cgccgcaggc ctcgccgacc ggtgcgaggt ccaggtggcc
     4081 tacgcgatcg gcgtggcgcg cccggtgtcg ctgatggtca acaccttcgg caccggccgc
     4141 atcgccgacg acaagatcgt cgagctcatc ggccgccact tcgacctgcg cccaaaggcg
     4201 atcatccaga cgctcgacct gctgcgcccg gtctactccc gcaccgcggc ctacggccac
     4261 ttcggccgcg acgagccggg cttcacctgg gagcagaccg acaaggccgc cgcgctgcgc
     4321 gccgacgccg ggctgtaagc ggggaattcg atgctccagc aagtcctgat gttcgccgcc
     4381 ggcctggcgg tgctggtcgt cggcgccgac gtgctggtgc gcggcgcctc gcggctggcc
     4441 gtctccttcg gcgtgtcgcc gctggtggtg ggccttaccg tggtcgcctt cggcaccagc
     4501 gcgcccgaga tggcggtgtc ggtgggctcg gcgctcgccg gcagccccga cctggcgatc
     4561 ggcaacgtgg tcggcagcaa catcgccaac gtgctgctga tcctcggcat ctcggcgctg
     4621 atcacgccgc tgctggtgga cgagcagatc atccgccagg agatcccgat catgatcggc
     4681 gcctcggcgc tcctggtggt gatggcgctc gacggcaaca tcggcctgct ggagtcgatc
     4741 gcactgttcg gcctggtgat cgcgtacacg gtcttcctgg tcgtgcagtc ccgccgtgcc
     4801 tcgaaagcgg tgcaggacga gttcgagacc gagatcccca cctccacctg ggaccgccac
     4861 tgggcggtgc aggtcggcct gatcgtgggc ggactggtga tgctggtggt cggcgccgac
     4921 tggctggtgg attcggcggt cgccttcgcg cgcgccttcg gcgtcagcga cctggtgatc
     4981 ggcctcacgg tggtcgcggt cggcacctcg atgcccgaga tcgccacgtc gatcgtcgcc
     5041 gccatccgcg gccagcgcga catcgcggtg ggcaacgtcg tcggcagcaa cgtgttcaac
     5101 ctcctcgccg tgctcggcgc cgccggcatc gcctcgggcg cggggctgcc ggtgtcggag
     5161 gcggcgcgca acttcgacct gtgggtgatg ctggcggtgg ccttcgcctg cctgccgatc
     5221 atgatcaccg ggcgcgagat cgcgcgctgg gagggcgggg tcttcctcgc ctactacgcc
     5281 gcctacaccg cctggctggt gctgcaggcg cagcagcacg ccagcctgcc ggcgttctcg
     5341 gggatcatgc tcggctacgt gctgccgctg acggtgatca cgctggtggt gagcctggtc
     5401 cgccagcaag gcaagaagcg cgccggctga gcaccgccgc aggcgcggcg gacacgctca
     5461 gccggcgacg cggaagcgtc cgaccgcgcg cgcaaggcca tcggcgagtc cgtcgagcgc
     5521 ctgcgcgcgc tgcagcgaat cgcgcgtggc ggtgtggctc cgctcgctca tgcgggcgat
     5581 ccgttccacg ctctgtgcga tgctggtgct ggtctcacgc tgctcacgca gcgcgaggct
     5641 gatctcgccc accacctggc gcacgcgtac cgtgccctcc tcgagcgcgc ccaccgcctc
     5701 gtgcgcacgc gccgcgcacg ccgcgccgcg gccagcgagt tcgcggccgt cctccatggt
     5761 gtcgaccgcc tggcgggcgc tgtcctgcac gcgctcgatc atggtgttga tctcctgcgt
     5821 cgactgcgcg gtgcgctcgg cgagcttgcg cacctcgtcg gccaccacgg cgaagccgcg
     5881 cccctgctcg cccgcacgcg ccgcttcgat cgcggcattg agggcgagca ggttggtctg
     5941 ctcggcgatg ccctggatga ccttggcgat gtccgagatg ctctcggcac gcgcgcccag
     6001 atcaccgacc accgccgccg aggccgacat gcgttcggag acgcggccga tcatgtccac
     6061 cgcctcgttg atcaccgccc cgccgtcgcg cacgcgctgc tcggcttcgc cgctgaagcg
     6121 gtcggcatcg tcggcgagct ccgcgaccac cgcgatgctg gcgctcatct cctcgaccgc
     6181 cgctgcgatc gattgcgcac cgtcgctctg ggccagtgcg gcgctcgcca cttcctcctc
     6241 gttgtggcgc aagccggcgg cggcctcgac cacccgcacg gcatcgccgc ggatctcgcg
     6301 cacgatcccg cccagcccgg actgcatcgc ctgcatcgcc accatcagac tatcgggacg
     6361 cgccgcggcg gcggtgatgt tctgctgcag atcgccctcg gtcatgcgtc gtgcaacggc
     6421 agccaccacc gcgggctcgc cgccgagctg gccgagcacc ccgcgcacca ccagcaccga
     6481 ggcgaccagg caggcgagca gggctgcgcc accgagggcg ctcacggtca gccggccgcg
     6541 ctcgatcgcc gccgccgagc tcgcgcgcgt cgccccagcc agcttctcca ggtgcgccac
     6601 ctgcttcatc agctcggcgc gcacctctcg ccaggccggc gtctccgacg ccaccagggt
     6661 gcgctgcgcc gccacgttgt cacccgcgcg cacgcgctcg atcacctgcg cctgcagcgg
     6721 cgcccagcgc tcggcgagct cgcgcagacg cgcggcggtc gccacgccgc catcgagtac
     6781 ggctggcgcg gcaagcaggc gggcgagcgt gtcgtcgaag ccggtcttcg ccgcctggaa
     6841 gttttcgtag gccttggggt tggcgggatc gagcaggatg ttgcgcaggg cctggcccat
     6901 ctgcaggccg tgtgcgtagg cgcgggtggc ctcgcgctcg gcggcgagtt cggtatcgat
     6961 gaaggccgac aggcgagcgc cgccggcctg gagctgccac accgccaccg cgagcgcaat
     7021 cgcgaacaag gtgcagctga cggcagcgag caggatcaac tgcgcgcgta cggtaagggt
     7081 tctggagctc atgtccggac tgcctcggaa gatgatcgga tcgcaacggc ccgccctcag
     7141 gggcgagccg atctcgatcg ggtctacggc agcccgggtc aaaactgaac cccgcgggac
     7201 cccggggagt ctcaagagcg atcgtcatgt cccgcggtgc aatgcagcgc atacatgtct
     7261 cggcgcgtac ggctgggcta tactcacgac tttccgagga gcgctgcgag gcgcccgccg
     7321 gctctgccgg ccgcggcccc caggctcgga ccccgccatc cggcgggttg cagtacaacg
     7381 gcgctcacct gctaatcgtc ttcaaccctg ccgggttcgg gatgtcgggt gagccgcctg
     7441 cagccatcgc acaagcctgc gtgctgccct cccccacctc tcgcccggcc atagcatgga
     7501 gcttcccatg aacgctgtgg ctgacaccaa gttcaccgat ttcgtcgtcg ccgacctcgc
     7561 gctcgccgcc tggggccgca aggaaatccg catcgccgag accgagatgc ccggcctgat
     7621 ggcgatccgc gaggaatacg ccgccagcca gcccctgaag ggcgcgcgca tcaccggctc
     7681 gctgcacatg accatccaga ccgcggtgct gatcgagacg ctgaccgcgc tcggcgccca
     7741 ggtgcgctgg gcctcgtgca acatcttctc gacccaggac cacgccgccg ccgccatcgc
     7801 ggccgacggc atcccggtgt tcgcggtcaa gggcgagtcg ctgaccgact actggaacta
     7861 cacccatcgc atcttcgagt ggccggacgg tggttacagc aacatgatcc tcgacgacgg
     7921 cggcgacgcc acgctgctgc tgcacctggg cgcacgcgcc gaacaggacc tctcggtgct
     7981 ggccaagccc ggctcggaag aggagaccat cctcttcgcc gcgatcaggg ccaagctggc
     8041 gcaggacccg acctggtatt cgacccgcct ggcgcaggtc aagggcgtga ccgaggagac
     8101 caccaccggc gtgcaccgcc tgtaccagat gcatgcgcgc ggcgagctca agttcccggc
     8161 gatcaacgtc aacgattcgg tgaccaagtc gaagttcgac aacctctacg gctgccgcga
     8221 gtcgctggtc gacggcatca agcgcgccac cgacgtgatg gtggccggca agatcgccgt
     8281 ggtgt
//
LOCUS       DAOTIN010000139         8234 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_10463_length_8234_cov_9.146595, whole genome shotgun sequence.
ACCESSION   DAOTIN010000139 DAOTIN010000000
VERSION     DAOTIN010000139.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 8234)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 8234)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8234
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_10463_length_8234_cov_9.146595"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(57..1178)
                     /locus_tag="P5537_14755"
     CDS             complement(57..1178)
                     /locus_tag="P5537_14755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HRV79348.1"
                     /translation="MIDQVAEKVVRRVILGFLLGGLLLLSYAVLHLFIVPVAWAVIIA
                     YATWPAHRQLRARLPRYPTITALLMTLLLSAAFVLPALWIGMLLRTEVGVAIAAVTAQ
                     IREGAFVLPEFVRTLPWIGDDLQAMLGELTREPEALRTQLTEWVRQGSDLVLTLIGDV
                     GRNAAKLGFALITVFFLYRDGEYVLEQVVAVLRRFLGERLDPYLAAVGGMTKAVVWGL
                     IATAIGQGFVAGLGYWWAGVPAPVLMGAITAVIAMIPFGTPFAWGSIGVWLLLTGNTV
                     EGIGLLLWGALVVSWVDNLVRPLVISNATRIPFLLVMFGVLGGLAAFGLVGLFLGPVV
                     LAVLMAVWREWLEESEFARLAAIASPAGGREEGEDAGRS"
     gene            complement(1175..2518)
                     /locus_tag="P5537_14760"
     CDS             complement(1175..2518)
                     /locus_tag="P5537_14760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HRV79349.1"
                     /translation="MEILFLIGLIVLNGVFAMSEIALVTARRARLARLAEEGDGAAEV
                     AIKLGEDPTRFLSTIQIGITSIGVLNGIVGEAALAGPLADWLQVMGMEQRVSEIGSTV
                     LVVVVITYVSIVVGELVPKRIGQIDPEGIARLVARPMNVLSIASRPFVYLLAGSTALL
                     LRIMGQRESTGPSVTEEEIHAMLVEGSEAGVIEKSEHDMVRNVFRLDDRQIGSLMVPR
                     ADIVSLDLNRPLEENLELVASSSYSSFPVCRGGLDDILGIASAKKLFNQSLRGEPIDL
                     AKDLQPAVYVPESLTGMELLDQFRSSGTYTVFVIDEYGEIQGMVTLHDVIESVTGEFL
                     PQDTEEAWAVQREDGSWLLDGLIPIVELKDRLGIKTVPEEEKGRYHTLSGMVMWLLGR
                     LPGTGDIATWESWRLEVIDLDGKRIDKVLASRLPEPADGIGAEQEAGTEDRSESA"
     gene            2943..3920
                     /locus_tag="P5537_14765"
     CDS             2943..3920
                     /locus_tag="P5537_14765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HRV79350.1"
                     /translation="MESIGTWWMWAAFAAIVVTMLLVDLFAFGGGKQHRVSLKEAAGW
                     SLAWVTVAMLFAAGLWWYLDGTLGRALANEQATAFVTGYLVEKSLAVDNVFVWMMIFS
                     FFAVPLELQRRVLLYGIVGAIVLRTIMIFAGSWLISEFHWLLYVFGAFLIVTGIKMAW
                     FSEHDPDLEKNPLIRWIRNHYPITEKLEGERFFVVRDGVRMMTPLFLALVLVEISDVI
                     FAVDSIPAIFAITTDPFIVLTSNLFAILGLRAMYFLLADLGDRFELLKYGLAAILVFI
                     GTKMLIVEWFKIPVLVSLSVVATILACSVFASLWYTARKQKEAATTRAG"
     gene            4035..>4564
                     /locus_tag="P5537_14770"
     CDS             4035..>4564
                     /locus_tag="P5537_14770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005216 - monoatomic ion channel activity
                     [Evidence IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HRV79351.1"
                     /translation="MTANLQRLVESAAFQRFIVAVIVVNAITLGLETSPTAMQQAGGL
                     LLALDRTALAIFVVEIVLKLIVYRQHFFRSGWNVFDFTIVAITLAPTGEGLQVLRSLR
                     ILRALRLVSVVPSMRKVVNALLRAIPGMSSVLTLLLLVFYVAAVMSTKLFGASFPDWF
                     GSVGESFYTLFQVMTL"
     assembly_gap    4565..4664
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <4665..4898
                     /locus_tag="P5537_14775"
     CDS             <4665..4898
                     /locus_tag="P5537_14775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HRV79352.1"
                     /translation="TTFAVLNLFIAIVVDSMSAVEHEEQEQTRELVSVDHDAVLAELR
                     AIRAELAELRGERTDDSAAAPAAVSAGSTARPG"
     gene            complement(4929..5333)
                     /locus_tag="P5537_14780"
     CDS             complement(4929..5333)
                     /locus_tag="P5537_14780"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HRV79353.1"
                     /translation="MRRLLSALALLPLTGAIAAGPQTTTLPSGITVETYRVGETGASP
                     TLADVVRVHYQGTLADGKEFDSSYSRGRPAELPLEALVPCWQEVLQQMKPGGAVRIVC
                     PPATAYGSRGVPGRIPPDSTLNFVIELLEVKR"
     gene            complement(5352..5738)
                     /locus_tag="P5537_14785"
     CDS             complement(5352..5738)
                     /locus_tag="P5537_14785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family
                     toxin"
                     /protein_id="HRV79354.1"
                     /translation="MNLLLDTHVALWAITDHPKLSQSARELILSPKSTVWVSVASVWE
                     IAIKHSLGRGDMPVSSQDAVRYFTASGYRLLAIEPEHVVAVEALPAHHQDPFDRLLVA
                     QALVEPMRLVTHDRFVALYSDTIIKI"
     gene            complement(5741..5983)
                     /locus_tag="P5537_14790"
     CDS             complement(5741..5983)
                     /locus_tag="P5537_14790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system
                     prevent-host-death family antitoxin"
                     /protein_id="HRV79355.1"
                     /translation="MQSVNMLQAKSSLSRLVDAIESGQEREIVIARNGRPAARLVPVE
                     DASAGPRIGVAKGRFEVPDDIDASNEDVARLFLAGG"
     assembly_gap    6078..6177
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(6313..>8234)
                     /gene="alaS"
                     /locus_tag="P5537_14795"
     CDS             complement(6313..>8234)
                     /gene="alaS"
                     /locus_tag="P5537_14795"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HRV79356.1"
                     /translation="MGLERISAVLQHVHANYEIDLFQALIKAAARETSGADMDSPSLK
                     VLADHIRACSFLIADGVIPGNEGRGYVLRRIIRRAIRHGYKLGARAAFFHKMVPDLVG
                     EMGGAYPELKDGERRIMDVLRQEEERFFATIENGMAIVEAELAAMEKAGNKVFDGDTA
                     FKLHDTFGFPLDLTADICREREVTVDALAFDAAMARQKEQARAAGKFKMAANLEYDGP
                     ETTFHGYTLLEEKGNILALYKDGAPVNELLEGEMGVVVLDHTPFYAESGGQVGDRGEL
                     RAAAGIFGVEDTQKIQAAVFGHHGVVRTGKLAVGQGVTARVDVAARAATARNHSVTHL
                     MHKALREVLGAHVQQKGSLVDPDKTRFDFAHTAPMSAEEIREVEEIVNREVLANAATQ
                     AEVMALEAAQKSGAMMLFGEKYADEVRVLSIGSSKELCGGTHVSRTGDIGLFKIVSEG
                     GVAAGIRRVEAITGENALRYAQEQERRVQGMSALLKVQPDEVAERVAGILDNVRALEK
                     ELARLKGKLAASQGDELVSQAVEVGGIKVLAALLEGADVPTLRDTMDKLKDKLKSAAI
                     VLASVGEGKVSLIAGVTADHTAKVKAGELVNFVAQQVGGKGGGRPDMAQAGGTQPENL
                     PAALAGVKEWVAGKL"
BASE COUNT         1241 a         2817 c         2677 g         1299 t
ORIGIN      
        1 gatccgggac gcggggtggt tcatgtagga gcgccggcag gcgcgaacgc ggcggatcag
       61 gatcgtccgg cgtcctcgcc ctcctcccgc cccccggcgg gcgaggcgat ggcggcgagg
      121 cgggcgaact cggactcctc cagccactcg cgccacaccg ccatcagcac cgccagcacc
      181 accgggccga ggaagagccc gaccaggccg aacgcggcca ggccgccgag cacgccgaac
      241 atcaccagca ggaaggggat gcgcgtggcg ttgctgatca ccagcgggcg caccaggttg
      301 tccacccagc tcaccaccag cgcgccccac agcagcaggc cgatgccctc gacggtgttg
      361 ccggtgagca gcagccacac cccgatcgaa ccccatgcga agggtgtgcc gaaggggatc
      421 atcgcgatca ccgcggtgat cgcccccatc agcaccggcg ccggcacgcc cgcccaccag
      481 tagcccaggc cggcgacgaa gccctggccg atcgcggtcg cgatcaggcc ccacaccacc
      541 gccttggtca tcccgcccac cgccgccaga taggggtcga ggcgctcgcc gaggaagcgg
      601 cgcagcaccg cgaccacctg ctccagcacg tactcgccgt cacggtagag gaagaacacc
      661 gtgatgagcg cgaaacccag cttggccgcg ttgcgcccga cgtcgccgat cagcgtcagc
      721 acgagatcgc tgccctggcg cacccactcg gtgagctggg tgcgcagcgc ctccggctcg
      781 cgggtgagtt cgcccagcat cgcctgcagg tcgtcgccga tccatggcag cgtgcgcacg
      841 aactcgggca gcacgaaggc gccctcgcgg atctgcgccg tgaccgcggc gatcgccacg
      901 ccgacctcgg tgcgcagcag catgccgatc cacagcgcgg gcagcacgaa ggccgcgctc
      961 agcagcaagg tcatcagcag cgcggtgatc gtggggtagc gcggcagccg cgcgcgcagc
     1021 tggcggtgag ccggccaggt ggcgtaggcg atgatcaccg cccacgccac cggcacgatg
     1081 aagaggtgca gcacagcgta gctcagcagc agcaggccgc cgaggaggaa gccgaggatg
     1141 acgcggcgga cgaccttctc ggcgacctgg tcgatcatgc gctctcgctc cgatcttccg
     1201 ttccggcttc ctgctcggcg ccgatcccgt cggccggctc gggcaggcga ctcgccagca
     1261 ccttgtcgat gcgcttgccg tcgaggtcga tcacctccag ccgccagctc tcccaggtgg
     1321 cgatgtcgcc cgtgcccggc aggcggccga gcagccacat caccatgccc gacagcgtgt
     1381 ggtagcgccc cttttcctct tccggcacgg tcttgatgcc gaggcggtcc ttgagctcca
     1441 cgatcgggat caggccgtcg agcagccagg agccgtcctc gcgctgcacc gcccaagcct
     1501 cctcggtatc ctgcggcagg aactcgccgg tcaccgactc gatcacgtcg tgcagcgtga
     1561 ccatgccctg gatctcgccg tattcatcga tcacgaacac ggtgtaggtg cccgacgagc
     1621 ggaactggtc gagcaactcc atgccggtga gcgactcggg cacgtacacg gcgggctgca
     1681 ggtccttggc gaggtcgatc ggctcgccgc gcagggactg gttgaagagc ttcttggcgc
     1741 tggcgatgcc gaggatgtcg tcgagtccgc cacggcacac cggaaagctg gagtaggacg
     1801 acgacgctac cagctcgagg ttctcctcca gcggccgatt caggtcgagc gacacgatgt
     1861 ccgcgcgcgg caccatcagc gagccgatct ggcgatcgtc gaggcggaac acgttgcgaa
     1921 ccatgtcgtg ctcgctcttc tcgatcacgc cggcctcgga gccctcgacc agcatggcgt
     1981 ggatctcctc ctcggtcacg ctcgggccgg tgctttcgcg ctggcccatg atgcgcagca
     2041 gcagggcagt cgatccggcg agcagataca cgaagggccg cgacgcgatc gacagcacat
     2101 tcatcggccg cgccaccagt cgggcgatgc cctcggggtc gatctggccg atgcgcttcg
     2161 gcaccagctc gccgaccacg atcgacacat aggtgatcac caccacgacc agcacggtcg
     2221 agccgatctc gctcacgcgc tgctccatgc ccatcacctg cagccagtcg gcgagcggtc
     2281 cggcgagcgc ggcctcgccg acgatgccgt tgagcacgcc gatcgaggtg atgccgatct
     2341 ggatcgtgga cagaaagcgg gtcgggtcct cgccgagctt gatcgccacc tcggccgcac
     2401 cgtcgccctc ctcggccagg cgtgcgagcc gcgcccggcg cgcagtgacg agcgcgatct
     2461 cggacatggc gaagacgccg ttgaggacga tgaggccgat caggaagagg atttccatgg
     2521 gttcgaggtg gttgaaaaag ggggcgccga cgagcgcccg ggcatgacgg gcgggccgga
     2581 cgccgccgat gatgccccag ccggcacggg gtgtcgaccg cgcccctgcg ccccgcgccc
     2641 gctcgctgct gcagcgcaac acctggaagc catggaccgc agcgatcgac ttcgacggcg
     2701 ttgacactcc cgcagcgcaa cagacacaat cctgcccatc aaggggagta gcttttccgc
     2761 tccggcatcg tcaatacggc agatcggtct tccgaccgtc tcccggtgcc gggggcaacg
     2821 ctcgaatccg ttcggccgtt gcaagcgaga ccttgcccga ggggcaaggt ccgtgcatcg
     2881 aagcgcgcca gggtctgtgt ccgtcgggaa caggcccttt ttgtttttgt gcggagcgcg
     2941 cgatggaatc gatcggaacg tggtggatgt gggcggcctt tgccgccatc gtggtaacga
     3001 tgctgctggt ggacctgttc gccttcggcg gcggcaagca gcaccgggtg tcgctgaagg
     3061 aggcagcggg ctggtccctc gcctgggtca cggtggcgat gctgttcgcg gccggtctgt
     3121 ggtggtacct cgacggcacg ctcgggcgtg cgctggccaa cgagcaggcg actgccttcg
     3181 tcaccggcta tctggtggag aagtcgctgg cggtcgacaa cgtcttcgtg tggatgatga
     3241 tcttcagctt cttcgcggtg ccgctggaac tgcagcgccg cgtactgctg tacggcatcg
     3301 tcggcgcgat cgtgctgcgc acgatcatga tcttcgcggg cagctggctg atcagcgagt
     3361 tccactggct gctctacgtc ttcggcgcct tcctgatcgt caccggcatc aagatggcgt
     3421 ggttctccga gcacgacccc gacctcgaga agaatcccct catccgctgg atccgcaacc
     3481 actacccgat caccgagaag ctggaaggcg agcgcttctt cgtggtgcgc gacggcgtgc
     3541 gcatgatgac gccgctcttc ctcgcgctcg tgctggtcga gatctcggat gtgatcttcg
     3601 cggtcgacag catcccggcg atcttcgcga tcaccaccga cccgttcatc gtgctgacct
     3661 ccaacctgtt cgcgatcctc ggcctgcgcg cgatgtactt cctgctcgcc gacctcggcg
     3721 accgcttcga gctgctcaag tacggcctgg ccgcgatcct ggtcttcatc ggcaccaaga
     3781 tgctgatcgt cgagtggttc aagatcccgg tgctggtgtc gctgtcggtg gtcgccacca
     3841 tcctggcgtg ctcggtgttc gccagcctgt ggtacacggc gcgcaagcag aaggaagcgg
     3901 ccacgacgcg cgcgggctga agctcgccgg ccgggacggc agggacggga cgtcgcacgc
     3961 ccgcccccgc cgtcgcggcg ccgtcggtcc gcctgtttct tcacccctga aaccgcacgc
     4021 atcctgctcg tcaaatgact gccaacctcc aacgcctcgt cgaatccgcc gccttccagc
     4081 gcttcatcgt cgcggtgatc gtcgtcaacg cgatcaccct cggcctcgag acctccccga
     4141 ccgccatgca gcaggccggc ggactgctgc tcgcgctcga ccgcaccgca ctcgccatct
     4201 tcgtggtcga gatcgtgctc aagctcatcg tctaccgcca gcacttcttc cgcagcggct
     4261 ggaacgtctt cgacttcacc atcgtcgcga tcaccctcgc ccccaccggc gaaggcctgc
     4321 aggtgctgcg ctcgctgcgc atcctgcgtg cgctgcgcct ggtgtcggtg gtgccctcga
     4381 tgcgcaaggt ggtcaacgcc ttgctgcgcg ccatccccgg catgagctcg gtgctcaccc
     4441 tgctgctgct cgtgttctac gtcgccgcgg tgatgagcac caagctgttc ggcgcgagct
     4501 tcccggactg gttcggcagc gtcggcgaat ccttctacac cctgttccag gtcatgaccc
     4561 tggannnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnaccacc ttcgcggtgc
     4681 tcaacctctt catcgccatc gtggtcgatt cgatgagcgc ggtggagcac gaagagcagg
     4741 agcagacgcg cgagctggtc agcgtggacc acgacgcggt gctcgccgag ctgcgcgcca
     4801 tccgcgccga gctggcggaa ctgcggggcg agcgcacgga tgattcggcc gctgcgcctg
     4861 ctgcggtcag cgcgggatcg actgcaaggc cgggctgatc cgtgacaggg cgcgcctgct
     4921 gcgtgccctc agcgcttgac ctcgagcagc tcgatcacga agttcagcgt gctgtcgggc
     4981 gggatgcggc ccggcacgcc gcggctgccg taggcggtcg cgggcgggca cacgatgcgc
     5041 accgcgccgc ccggcttcat ctgctgcagc acctcctgcc agcacggcac cagcgcctcc
     5101 agcggcagct cggcagggcg gccgcggctg taggagctgt cgaactcctt gccgtcggcg
     5161 agcgtgccct ggtaatgcac gcgcaccacg tcggccagcg tcggcgacgc gccggtctcc
     5221 cccacgcggt aggtctcgac ggtgatgccc gagggcaggg tcgtggtctg tgggccggcg
     5281 gcgatcgcgc cggtgagggg aagcagggcg agggcagaaa gcagtcggcg catgtcgaga
     5341 actccgggaa ttcagatctt gatgatcgta tcgctgtaga gcgccacgaa acgatcgtgc
     5401 gtcaccaggc gcatcggctc gaccagcgcc tgcgccacca gaagacggtc gaaagggtcc
     5461 tgatgatgcg cgggcaaggc ctcgaccgcc acgacgtgct cgggctcgat cgcgagcagg
     5521 cgatagcccg aggcggtgaa atagcgcacg gcatcctggc tggagaccgg catgtcgcca
     5581 cgcccgaggg aatgcttgat ggcgatctcc cagacgctgg cgacgctgac ccagaccgtc
     5641 gatttcggcg acaggatcag ctcacgcgcg ctctgcgaca gcttggggtg gtcggtgatg
     5701 gcccacagcg cgacatgcgt gtcgaggagc agattcaaga tcagcctccc gccaggaaca
     5761 gcctcgcgac gtcctcgttg ctggcgtcga tgtcgtcggg cacctcgaac ctgcccttgg
     5821 ccaccccgat gcggggtccc gcggacgcgt cctccaccgg cacgagccgg gcggcagggc
     5881 ggccgttgcg ggcgatgacg atctcgcgct cctggcccga ctcgatcgcg tcaacgaggc
     5941 gggacaggga tgactttgcc tgcagcatgt tgacggattg cattgggacc tccctggaga
     6001 cttacctagt ctagtctggc taacccggtc cggcaaacaa gcgctcaaag cattccgcag
     6061 cgcatcgacc gcagcgcnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnccg
     6181 cagcgcatcg accgcagcgc ccccacccaa gcccgttccc aaaaaagacg cccggcaatc
     6241 gccgggcgtc ctcatgcatg cagggccaga gcacacgagc gccgctcgcg ctcgccgccc
     6301 tcaagcccgc gcttacagct tcccggccac ccactccttc acccccgcca gcgccgccgg
     6361 caggttctcg ggctgggtgc cgccggcctg ggccatgtcg gggcggccgc cgcccttgcc
     6421 gccgacctgc tgggcgacga agttcaccag ctcgccggcc ttgaccttgg cagtgtggtc
     6481 ggcggtgacg ccggcgatca ggctgacctt gccctcgccc acgctcgcca gcacgatcgc
     6541 ggccgacttc aacttgtcct tgagcttgtc catggtgtcg cgcagggtgg gcacgtcggc
     6601 gccttcgagc agggcggcga gcaccttgat accgcccacc tccaccgcct ggctcaccag
     6661 ctcgtcgccc tggctggcag cgagcttgcc cttgaggcgg gcgagctcct tctcgagtgc
     6721 gcgcacgttg tcgaggatgc cggcgacgcg ctcggcgacc tcgtcgggct gcaccttgag
     6781 cagcgcggac atgccctgca cgcggcgctc ctgctcctgg gcgtagcgca gcgcgttctc
     6841 gccggtaatg gcttcgacgc ggcggatgcc ggcggccaca ccgccctcgg acacgatctt
     6901 gaaaaggccg atgtcgccgg tgcgggagac gtgggtgccg ccgcacagct ccttggagct
     6961 gccgatcgac agcacgcgca cctcgtcggc gtacttctcg ccgaacagca tcatcgcacc
     7021 cgacttctgc gccgcctcca gcgccatgac ctcggcctgc gtcgcggcgt tggcgaggac
     7081 ctcgcggttg acgatctcct cgacctcgcg gatctcctcg gcgctcatcg gcgcggtgtg
     7141 ggcgaagtcg aagcgggtct tgtcgggatc gaccagcgag cccttctgct gcacgtgggc
     7201 gccgagcacc tcgcgcagcg ccttgtgcat caggtgggtg accgagtggt tgcgcgcggt
     7261 ggcggcacgc gcggcgacgt cgacccgggc ggtcacgccc tgccccaccg cgagcttgcc
     7321 ggtgcgcacc acgccgtggt ggccgaagac cgcggcctgg atcttctgcg tgtcttccac
     7381 gccgaagatg ccggcggcag cgcgcagctc gccgcggtcg ccgacctggc cgccggactc
     7441 ggcgtagaac ggcgtgtggt cgagcacgac cacgcccatc tcgccctcga gcagctcgtt
     7501 gaccggggcg ccgtccttgt acagcgcgag gatgttgccc ttctcctcca gcagcgtgta
     7561 gccgtggaag gtagtctcgg ggccgtcgta ttccaggttg gccgccatct tgaacttgcc
     7621 ggcggcgcgc gcctgctcct tctggcgcgc catcgccgcg tcgaaggcga gcgcatccac
     7681 ggtgacctca cgctcgcggc agatgtcggc ggtgagatcg agcgggaagc cgaaggtgtc
     7741 gtgcagcttg aaggcggtgt cgccgtcgaa gaccttgttg cccgccttct ccatcgcggc
     7801 gagctcggcc tcgacgatgg ccatgccgtt ctcgatggtg gcgaagaagc gctcttcctc
     7861 ctggcgcagc acgtccatga tgcggcgctc gccgtccttg agctcggggt aagcgccgcc
     7921 catctcgccg accaggtcgg ggaccatctt gtggaagaag gcggcgcgcg cgccgagctt
     7981 gtagccgtgg cggatggcgc ggcggatgat gcggcgcagc acgtagccgc gcccctcgtt
     8041 gcccgggatc acgccgtcgg cgatcaggaa ggagcaggcg cggatgtggt cggccagcac
     8101 cttcagcgag ggcgaatcca tgtcggcgcc ggaggtctcg cgcgcggcgg ccttgatcag
     8161 cgcctggaac aggtcgatct cgtagttggc gtgcacgtgc tgcagcaccg cggagatgcg
     8221 ctccaggccc atgc
//
LOCUS       DAOTIN010000140         8186 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_10540_length_8186_cov_8.543968, whole genome shotgun sequence.
ACCESSION   DAOTIN010000140 DAOTIN010000000
VERSION     DAOTIN010000140.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 8186)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 8186)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8186
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_10540_length_8186_cov_8.543968"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            158..1012
                     /locus_tag="P5537_14800"
     CDS             158..1012
                     /locus_tag="P5537_14800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004374810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HRV79357.1"
                     /translation="MDFRNGRESNNVEDRRGQGGRGLRGGGKIGIGTIVLALVAMYFG
                     IDPSVVLNTAMTDPAPVESTQPRPAAENAQARFVSMVLADTEDTWRVIFQQGGATYRE
                     PKLVLYTGATRSACGVGQAEMGPFYCPADAKVYLDLAFFDELHHRFGAPGDFAQAYVI
                     AHEIGHHVQNLLGISDKVQQARGRVSEREANLLSVRLELQADCLAGIWAHHANRSRSV
                     LEAGDIEEGLAAASAVGDDHIQKRTQGYAVPDSFTHGSAEQRRRWFGIGLQEGRFQAC
                     DTFSAARL"
     assembly_gap    1109..1208
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            1316..1798
                     /locus_tag="P5537_14805"
     CDS             1316..1798
                     /locus_tag="P5537_14805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004374807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2384 domain-containing protein"
                     /protein_id="HRV79358.1"
                     /translation="MTSLAEVSSLGPRRSLAAADVIDAVVDWAPDDRIDVLRSGFPAG
                     VVAQLAGRMGWSKERTIDALKLKRSTVLRKIKEARRLDTPDSERLMAVMDMIAQVERM
                     VTRSGEPEGFDAALWLAGWLDAPCPALGGQRPSDYLDTNEGIQVVRGVLARMESGAYA
                     "
     gene            1795..2286
                     /locus_tag="P5537_14810"
     CDS             1795..2286
                     /locus_tag="P5537_14810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004374804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RES family NAD+ phosphorylase"
                     /protein_id="HRV79359.1"
                     /translation="MKVAVPVWRIATDTPDYTADDLAGTGAKSSGGRWNRKGTAMVYT
                     SGSAALACLETLVHLATNPLPLNRYLVRVEIPHAAFMARLRLDDLVAAERQVGWDAEP
                     AGKVSLDLGTAWVEGMRSAVLEVPSVVLPEESNFLINPLHPDAAGIRAVKLRRFEYDR
                     RLR"
     assembly_gap    2583..2682
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(3197..5185)
                     /gene="accC"
                     /locus_tag="P5537_14815"
     CDS             complement(3197..5185)
                     /gene="accC"
                     /locus_tag="P5537_14815"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002945519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HRV79360.1"
                     /translation="MFKKILIANRGEITCRVIKTARKMGIKTVAVYSEADKNALHVEL
                     ADEAVCIGPAPSKESYLVMDKIIAACKQTGAEAVHPGYGFLSENAEFSRRLEEEGIKF
                     IGPKHYSVAKMGDKIESKKLAIAAGVNTIPGYNDAISGPDEAVEIAKKIGYPVMIKAS
                     AGGGGKGLRVAFNDKEAHEGFASCVNEARNAFGDDRVFIEKYVLEPRHIEIQVLGDGH
                     GNYVYLNERDCSIQRRHQKVIEEAPSPFVDPAMRKAMGEQAVALARAVNYESAGTVEF
                     VVSGATKEFYFLEMNTRLQVEHPVTELITGLDLVEQMIRVAYGEKLPLTQADVGIDGW
                     AMECRINAEDPFRGFLPSTGRLIKFQPPAEGNGVRVDTGVYEGGEISMFYDSMIAKLI
                     VHGKDRQDAIERMRDALNGFVIRGISSNIPFQAALLQHPRFCSGNFNTGFIAEEYPKG
                     FDASMVPHDDPALLAAVATFARMRYIERAVQIEGQLAGHGRKVADEWVVVMGGKQYPM
                     TTAPIEGGLAVTSAGKTYNIVSDWKFGELLFSGTVNGAPIGLQIERRGLRYRISHFGL
                     QVEPMVMTVRAARLLSLMPEKLPPDLSKFLLSPMPGLLREVAVSEGQDVKAGEKLAII
                     EAMKMENVLKAEQDGKVKKIVAKPGASLSVDEVIIEFE"
     gene            complement(5209..6741)
                     /locus_tag="P5537_14820"
     CDS             complement(5209..6741)
                     /locus_tag="P5537_14820"
                     /EC_number="6.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005796758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="HRV79361.1"
                     /translation="MQDIIRQLEQKRELARLGGGQKRIDAQHRKGKLTARERIELLLD
                     DDSFEEWDMYKEHRCTEFGMDAEHIPGDGVVTGYGTVNGRLVFVFSQDFTVFGGSLSE
                     THAEKICKVMDHAMKVGAPVIGLNDSGGARIQEGVDSLGGYADVFQRNVLASGVIPQI
                     SLIMGPCAGGAVYSPAMTDFIFMVKDSSYMFVTGPEVVKTVTHEEVTAEELGGAVTHN
                     TKSGVADLAFENDVEALMMTRRLIGFLPSSNREKPPAIPCADSADRIDLSLDTLVPEN
                     PNQPYDMKELIFKMVDDGDFFELQPDYAKNIIIGLARMEGSPVGIVANQPLVLAGCLD
                     IKSSIKAARFVRFCDAFNIPVVTLVDVPGFMPGTSQEYGGIIKHGAKLLYAYAECTVP
                     KVTLITRKAYGGAYDVMSSKHLRGDVNLAWPSAEIAVMGAKGAVEIIFREEKGDPEKL
                     AQREAEYKARFANPFVAASRGFIDDVVMPHNTRKRICRSLAMLRDKQLDNPWRKHGNI
                     PL"
     gene            complement(6790..7785)
                     /gene="meaB"
                     /locus_tag="P5537_14825"
     CDS             complement(6790..7785)
                     /gene="meaB"
                     /locus_tag="P5537_14825"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl Co-A mutase-associated GTPase
                     MeaB"
                     /protein_id="HRV79362.1"
                     /translation="MSTLDPADQSLVAGVLARQLRPLAKTITLIESQREDHQARAQQV
                     LEALLPHTGGAMRVGISGVPGVGKSTFIEALGLYLIEQGLRVAVLAVDPSSSVTGGSI
                     LGDKTRMELLSQNPAAFIRPSPSACSLGGVAEKTRETMLVCEASGFDVIIVETVGVGQ
                     SETAVAGMTDIFCLLQLPNAGDDLQAIKKGIMEIADLIVINKADIDAGAAMRAKAQIK
                     TALHMLRPASPNWTVPVLTLSALQKQGIADFWKAVSDYREALTASGEFAAKRRHQALA
                     WMWEMIDSGLRSRFRSHPRVREELPALARAVEEGGTTPAAAAFRLLGHLQSNAQG"
     gene            complement(7785..>8186)
                     /locus_tag="P5537_14830"
     CDS             complement(7785..>8186)
                     /locus_tag="P5537_14830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002934063.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0031419 - cobalamin binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HRV79363.1"
                     /translation="RPRVMIAKLGQDGHDRGAKVVASAFADLGFDIDIGPLFQTPEEA
                     ARHAVENDVHAVGCSSLAAGHKTLVPAVINELKRLGADDIITFVGGVIPAQDYDTLYA
                     AGAKGIFGPGTPIPAAAREVLKQIRAARAKA"
BASE COUNT         1153 a         2394 c         3069 g         1370 t
ORIGIN      
        1 cggtttctgt aggagcgccg gcaggcgcga aagcggcgat gacggtgcgg ccgacgtcgg
       61 cgcagggcgg gggcgattcg tttcggtgcg ccgggcttgc cacgggggcg ccgcgctcac
      121 taagctgaat gtattcccca cgaatggagt gcacgccatg gacttccgca acggcaggga
      181 gagcaacaac gtcgaggacc gccgcggaca aggcggacgc gggctgcgcg gtgggggcaa
      241 gatcggcatc gggacgatcg tgctggcgct ggtggcgatg tacttcggca tcgatccgag
      301 cgtggtgctc aacacggcga tgaccgaccc ggcgccggtc gaatcgaccc agccgcgccc
      361 cgcggccgag aacgcgcagg cgcgcttcgt gtcgatggtg ctggccgaca ccgaggacac
      421 ctggcgggtg attttccagc agggcggcgc gacctaccgc gagcccaagc tggtgctgta
      481 caccggcgcc acgcgcagcg cctgcggcgt cgggcaggcg gagatggggc cgttctactg
      541 ccctgcggac gccaaggtgt atctcgacct ggccttcttc gacgagctgc atcatcgctt
      601 cggcgcgccg ggggattttg cccaggcgta cgtgatcgcg cacgagatcg gccatcatgt
      661 gcagaacctg ctggggattt cggacaaggt gcagcaggcg cgcggacggg tatcggagcg
      721 tgaggcgaac ctgctctcgg tgcggctgga gctgcaggcg gactgcctgg cgggcatctg
      781 ggcccaccac gccaaccgca gccgcagcgt gctggaggcc ggcgacatcg aggaaggcct
      841 tgccgcggcc agcgcggtgg gcgacgacca tattcagaag cgcacccagg gctacgcggt
      901 gcccgacagc ttcacccacg gcagcgccga gcaacgccgc cgctggttcg gcatcggcct
      961 gcaggagggg cgcttccagg cctgcgacac gttcagcgcg gcgaggttgt agttcggccg
     1021 tagaagctcg cgcctgccgg cgctcctaca gggaggcgtc gccgcgggag cgtggtcgca
     1081 tccgaaaacg tgatccccaa ccggcaacnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1141 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1201 nnnnnnnntt cgcgcctgcc ggcgctccta cacgaggttg tcgcagctga ggcggcctca
     1261 ctccgtccta tcctggccat tcgactgtct ataatgagac aaaaggagga tggccatgac
     1321 ttcacttgca gaggtgtcga gccttgggcc gcgccggagc ctggcggcgg cggatgtgat
     1381 cgacgcggtg gtcgattggg cgccggacga tcggatcgat gtgctgcgca gcggctttcc
     1441 ggccggggtg gtggcgcagt tggctgggcg catggggtgg tccaaggagc gcacgatcga
     1501 tgcgctcaag ctcaagcgct cgacggtgct gcgcaagatc aaggaggcgc ggcggctcga
     1561 cacgccggat tccgagcgtc tgatggcggt gatggacatg atcgcccagg tcgagcgcat
     1621 ggtgacgcgc tcgggcgagc cggagggctt cgacgcggcg ctgtggctgg cgggctggct
     1681 ggacgcgccc tgccccgcgc tgggcgggca gcggccgagc gattacctgg acaccaacga
     1741 gggcatccag gttgtgcgcg gggtgctggc gcggatggaa agcggagcct acgcgtgaag
     1801 gtggcggtgc cagtgtggcg gatcgcgacc gatacgccgg actacacggc ggacgacctg
     1861 gccggaactg gcgcgaagtc gagcggcgga cgctggaacc gcaaggggac ggcgatggtg
     1921 tacacgtcgg gctcggcagc gctggcctgc ctggagacgc tggtgcatct ggcgacgaat
     1981 ccgctgccct tgaaccggta tctggtgagg gtggagattc cgcacgcggc gttcatggca
     2041 cggctgcggc tggacgacct ggtggcggcg gagcgtcagg tgggctggga cgcggagccg
     2101 gcgggcaagg tgagcctgga tctggggacg gcgtgggtgg aggggatgcg ctcggcggtg
     2161 ctggaggtgc cgtcggtggt gctgccggag gagtcgaatt tcctcatcaa cccgctgcat
     2221 ccggacgcag cggggatccg ggcggtgaag ttgcgccgct tcgagtacga ccggcgcctg
     2281 aggtgatttc accgccgctt tcgcgcctgc cggcgctcct acatgggggc gtcgcggcgg
     2341 agaggtggtc gcgggcggtg gagaggtggt cgcgggcggc ggaggtggtc gcgcgcggtg
     2401 gagaggtggt cgcgtgtggc ggaggtgggg tcgcgggcga caggaattga tcgcggtcgg
     2461 ggtgggatgt aggagcggcg gcagccgcga attgggcggt ggggtggcgg cgtggtcggg
     2521 aatttcgccg ccgctttcgc gcctgccggc gctcctacat gggggcgtcg cggcggagag
     2581 gtnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nngggtggga tgtaggagcg
     2701 gcggcagccg cgaattgggc ggtggggtgg cggcgtgatc gggaatttcg ccgctgcttt
     2761 cgcgcctgcc ggcgctccta catgggggcg tcgcggcgga gaagtggtcg cgggcggcgg
     2821 aggtggggtc gcgggcgaca ggaattgatc gcggtcgggg tgggatgtag gagcggcggc
     2881 agccgcgaat tgggcggtgg ggtggcggcg tggtcgggaa tttcgccgcc gctttcgcgc
     2941 ctgccggcgc tcctacatgg gggcgtcgcg gcggagaggt ggtcgcgtcg cggtggagag
     3001 gtggtcgcgc gcggtggagg tggtcgcgcg cggcgaatcg cagaaaaaag aggcctgctt
     3061 gcgcaggcct cgagccgaca ggcacccggg ccgtggcccg ggtctccctc cccatcgatc
     3121 aaaacggttg tccgggccgg cgtgggtggc gggcgcgaac ggagcgcatc ccgctacgcc
     3181 ggctcggggc ggcggatcat tcgaactcga tgatgacctc gtccaccgac aggctggcgc
     3241 cgggcttggc gacgatcttc ttgaccttgc cgtcctgctc ggccttgagg acgttctcca
     3301 tcttcatggc ttcgatgatg gcgagcttct cgccggcctt gacgtcctgg ccttcgctca
     3361 ccgcgacctc gcgcagcagg ccgggcatcg gggagagcag gaacttggac aggtcgggcg
     3421 gcagcttctc gggcattagc gagagcaggc gggcggcgcg cacggtcatc accatcggtt
     3481 cgacctgcag gccgaagtgc gagatgcggt agcgcaggcc gcggcgttcg atctgcaggc
     3541 cgatcggggc gccgttgacg gtgccggaga acagcaactc accgaacttc cagtcggaga
     3601 cgatgttgta ggtcttgccg gcgctggtga cggcgaggcc gccttcgatc ggcgcggtgg
     3661 tcatcgggta ctgcttgccg cccatgacga cgacccattc gtcggcgacc ttgcggccgt
     3721 ggccggcgag ctggccttcg atctgcacgg cgcgctcgat gtagcgcatg cgggcgaagg
     3781 tggcgacggc ggcgagcagc gcggggtcgt cgtgcgggac catcgaggcg tcgaagccct
     3841 tcgggtactc ctcggcgatg aagccggtgt tgaagttgcc cgagcagaag cgcgggtgct
     3901 gcagcagcgc ggcctggaag gggatgttgg agctgatgcc gcggatgacg aagccgttga
     3961 gggcgtcgcg catgcgctcg atggcgtcct ggcggtcctt gccgtgcacg atgagcttgg
     4021 cgatcatcga gtcgtagaac atcgagatct cgccgccttc atacacgccg gtgtcgacgc
     4081 gcacgccgtt gccttcggcc gggggctgga acttgatgag gcggccggtg gagggcagga
     4141 agccgcggaa ggggtcttcg gcgttgatgc ggcactccat cgcccagccg tcgatgccga
     4201 cgtcggcctg ggtgagcggc agcttttcgc cgtaggcgac gcggatcatc tgctcgacga
     4261 ggtccagccc ggtgatgagc tcggtgaccg ggtgctcgac ctgcaggcgg gtgttcatct
     4321 cgaggaagta gaactccttg gtcgcgccgc tgacgacgaa ctcgaccgtg ccggccgact
     4381 cgtagttcac cgcgcgcgcc agggccacgg cctgctcgcc catggccttg cgcatcgcgg
     4441 ggtcgacgaa ggggctcggc gcctcctcga tgaccttctg gtgacggcgc tggatggagc
     4501 agtcgcgttc gttcaggtag acgtagttgc cgtgaccgtc accgaggacc tggatctcga
     4561 tgtggcgcgg ctcgagcacg tacttctcga tgaagacgcg gtcgtcgccg aaggcgttgc
     4621 gggcctcgtt gacgcaggag gcgaagcctt cgtgcgcttc cttgtcgttg aaggcgacgc
     4681 gcaggccctt gccgccaccg ccggcggagg ccttgatcat gaccgggtag ccgatcttct
     4741 tggcgatctc gaccgcctcg tcggggccgg agatggcgtc gttgtagccg gggatggtgt
     4801 tcacgccggc agcgatggcg agcttcttgg actcgatctt gtcgcccatc ttggccaccg
     4861 agtagtgctt cgggccgatg aacttgatgc cttcctcttc cagccggcgc gagaactcgg
     4921 cgttctcgga caggaagccg tagcccgggt ggaccgcctc ggcgccggtc tgcttgcagg
     4981 cggcgatgat cttgtccatg accaggtagg actctttcga gggcgccggg ccgatgcaga
     5041 cggcttcgtc ggcgagctcg acgtggagcg cgttcttgtc cgcctcggag tagaccgcga
     5101 cggtcttgat gcccatcttg cgggcggtct tgatgacgcg gcaggtgatc tcgccacggt
     5161 ttgcaatcag gattttcttg aacatttggt cggttcctcg tgcgcggatc agagcgggat
     5221 gttgccgtgc ttgcgccacg ggttgtcgag ctgcttgtcg cgcaacatgg ccagcgagcg
     5281 gcagatgcgc ttgcgggtgt tgtgcggcat gaccacgtcg tcgatgaagc cgcggctggc
     5341 ggcgacgaag gggttggcga aacgggcctt gtactcggct tcgcgctggg cgagcttctc
     5401 gggatcgccc ttctcttcgc ggaagatgat ctcgaccgcg cccttggcgc ccatcacggc
     5461 gatctcggcg ctcggccagg cgaggttgac gtcgccgcgc aggtgcttgg acgacatcac
     5521 gtcgtaggcg ccaccgtagg ccttgcgggt gatcagggtg accttgggca cggtgcactc
     5581 ggcgtaggcg tagagcagct tggcgccgtg cttgatgatg ccgccgtatt cctgcgaggt
     5641 gccgggcatg aagccgggga cgtcgaccaa ggtgacgacc ggaatgttga aggcgtcgca
     5701 gaagcgcacg aagcgggcgg ccttgatcga gctcttgatg tcgaggcagc cggccagcac
     5761 gagcggctgg ttggcgacga tgcccaccgg cgagccttcc atgcgcgcca ggccgatgat
     5821 gatgttcttg gcgtagtcgg gctgcagttc gaagaagtcg ccgtcgtcga ccatcttgaa
     5881 gatgagctcc ttcatgtcgt acggctggtt cgggttctcc ggcaccaggg tgtcgagcga
     5941 caggtcgatg cggtcggcgg agtcggcgca gggaatcgcg ggcggcttct cgcggttgct
     6001 ggagggcagg aagccgatca ggcggcgcgt catcatcagc gcctcgacgt cgttctcgaa
     6061 ggcgaggtcg gcgacgccgg acttggtgtt gtgggtgacg gcgccgccga gctcctcggc
     6121 ggtgacttcc tcgtgggtca cggtcttcac gacctcggga ccggtcacga acatgtagga
     6181 cgagtccttg accatgaaga tgaagtcggt catggccggg ctgtacaccg cgccgccggc
     6241 gcaggggccc atgatcagcg agatctgcgg gatgacgccg gaggcgagca cgttgcgctg
     6301 gaagacgtcg gcgtagccgc cgagcgagtc cacgccttcc tggatgcggg cgccgcccga
     6361 gtcgttgagg ccgatcaccg gggcgccgac cttcatggcg tggtccatga ccttgcagat
     6421 cttctcggcg tgggtctcgg agagcgagcc gccgaagacg gtgaagtcct gcgagaagac
     6481 gaagaccagg cggccgttga cggtgccgta gccggtgacc acgccgtcac cggggatgtg
     6541 ctcggcgtcc atgccgaact cggtgcagcg gtgctccttg tacatgtccc actcttcgaa
     6601 gctgtcgtcg tcgagcagca gttcgatgcg ctcgcgcgcg gtgagcttgc ccttgcggtg
     6661 ctgcgcgtcg atgcgcttct ggccgccacc gaggcgggcc agttcgcgct tctgctcgag
     6721 ctggcgaatg atgtcttgca tgagtgtgat ctcctgtcag atctcggttt cggccggctg
     6781 ccgcggcagt caaccctgtg cgttggactg gaggtggccg agcagccgga aggctgcggc
     6841 cgcgggcgtg gtgccgccct cctcgaccgc gcgtgcgagg gcggggagtt cctcgcgcac
     6901 gcgggggtgg ctgcggaaac ggctgcgcag cccggaatcg atcatctccc acatccaggc
     6961 gagcgcctgg tggcgacgct tggcggcgaa ctcgccggag gcggtcagcg cctcgcggta
     7021 gtcgctcacc gccttccaga agtcggcgat gccctgcttc tgcagcgccg acagggtgag
     7081 caccggcacg gtccagttgg ggctggccgg gcgcagcatg tgcagcgcgg tcttgatctg
     7141 cgccttggcg cgcatggcgg cgccggcgtc gatgtcggcc ttgttgatga cgatcaggtc
     7201 ggcgatctcc atgatgcctt tcttgatcgc ctgcaggtcg tcgccggcgt tggggagctg
     7261 cagcaggcag aagatgtcgg tcatgccggc gaccgcggtc tcggactgcc cgacaccgac
     7321 ggtctcgacg atgatgacgt cgaagccgga ggcctcgcac accagcatgg tctcgcgcgt
     7381 cttctcggcc acgccgccca ggctgcaggc ggaggggctg gggcggatga aggcggcggg
     7441 gttctgcgac agcagctcca tgcgcgtctt gtcgccgagg atggaaccgc cggtgaccga
     7501 cgaggacggg tcgaccgcca gcaccgcgac gcgcaggccc tgctcgatga ggtagagccc
     7561 gagcgcctcg atgaaggtgc tcttgcccac gcccggcacg cccgagatgc cgacgcgcat
     7621 cgccccgccg gtatgcggca gcagggcctc gagcacctgc tgcgcgcgcg cctggtggtc
     7681 ctcgcgctgc gattcgatca gcgtgatggt cttggcgagc ggccgcagct gacgcgccag
     7741 cacgccggcg acgagggact ggtcggcagg atcgagcgtg ctcatcaggc cttggcgcga
     7801 gccgcgcgga tctgcttgag cacctcgcgc gccgccgccg ggatcggcgt gccggggccg
     7861 aagatgccct tggcgccggc ggcgtacagg gtgtcgtagt cctgcgccgg gatgacgcca
     7921 ccgacgaagg tgatgatgtc gtcggcgccg aggcgcttga gctcgttgat gacggcgggc
     7981 acgagggtct tgtggccggc ggcgaggctg gagcagccga ccgcgtgcac gtcgttctcg
     8041 acggcgtggc gggcggcctc ttccggggtc tggaagagcg ggccgatgtc gatgtcgaag
     8101 ccgaggtcgg cgaaggccga ggcgaccacc ttggcgccgc ggtcgtggcc gtcctggccg
     8161 agcttggcga tcatcacgcg cgggcg
//
LOCUS       DAOTIN010000141         8017 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_10835_length_8017_cov_10.239387, whole genome shotgun
            sequence.
ACCESSION   DAOTIN010000141 DAOTIN010000000
VERSION     DAOTIN010000141.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 8017)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 8017)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8017
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_10835_length_8017_cov_10.239387"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            455..742
                     /gene="pqqD"
                     /locus_tag="P5537_14835"
     CDS             455..742
                     /gene="pqqD"
                     /locus_tag="P5537_14835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004319064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0048038 - quinone binding [Evidence IEA];
                     GO_process: GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroloquinoline quinone biosynthesis peptide
                     chaperone PqqD"
                     /protein_id="HRV79364.1"
                     /translation="MDTATLPADARPRLSPHYVFRWEESQSAFILLYPEGLIKLNPSA
                     GAVLERCDGARTVAAIVAELQAAFPAQAAEIADGVRAFVDLACDKGWLRAA"
     gene            742..1794
                     /locus_tag="P5537_14840"
     CDS             742..1794
                     /locus_tag="P5537_14840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HRV79365.1"
                     /translation="MDAAPALPAGAPPAGASPLFAGAAPFATHRLAVGDGHVLHVEEC
                     GRADGIAVVFLHGGPGSGCSPRQRRLFDPARFRAVLFEQRGAGRSTPSGGLRANTTAH
                     LVADIERIRAALAIERWIVFGGSWGSLLALEYACAHPDRVAGLVLRGIFLASAAELRA
                     YVGRIPPQAPGLRESLEREARIRLPRMRSPQAEDDLLAAWCRCTLAGRPATQRAAARH
                     WLDHERALMGEPPLPGPPDARELAKARIQAHYLAHGCFTDAARLLAACAALRHLPAAI
                     VHGADDPVCPPATARALHRALPEADYVEIPGAGHAGLAPEMAAACITALDRVATRAHP
                     GHAAGHTALHAAQRAR"
     gene            1887..3032
                     /gene="pqqE"
                     /locus_tag="P5537_14845"
     CDS             1887..3032
                     /gene="pqqE"
                     /locus_tag="P5537_14845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0018149 - peptide cross-linking [Evidence
                     IEA];
                     GO_process: GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="HRV79366.1"
                     /translation="MPKETHGLSLDGQGKPLWLSLELTYRCPLKCTWCNNPLDFEDYA
                     AKELSTEEWKQVLRDAREIGALQLGFTGGEPLQRADLEELVACADGLGFYTNLITSGI
                     GLNEERLLALKAAGLKQIQLSLQSTRADMTDALVGARAHAHKLEAARLIKAHGFPMVL
                     NMPVFRHNIELIGEMIEWAAGLGVEYIEFANIQYYNWALLNRDELMPTLEQVREAERV
                     VNEWRARLGKAMTIYFVIPDYYEGRPKACMNGWGAIHLTIAPDGVAMPCQEARVIPGL
                     EFESVRDQPLGWIWHESPLFRKYRGLDWLPEPCGSCSEKEKDFGGCRCQAFLLTGDAA
                     NTDPACSRSPHHHLVQQAVAGVVAPLRFRKPLIKRAAGAVSTAFMEG"
     gene            3136..3636
                     /locus_tag="P5537_14850"
     CDS             3136..3636
                     /locus_tag="P5537_14850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urate hydroxylase PuuD"
                     /protein_id="HRV79367.1"
                     /translation="MDPLLDLALRWTHFIAGIIWVGHNYSSVVQRPGWRPLAAADLTD
                     DTSPRFQALLNREHGFFRWASVVAWSAGLLMLWQRGWLTGALTLDGALAPIGLGTWIG
                     TLMMLNVWFVLWPHQQKVLGLVPASVDERLRCSRITHLSSRTNTMLSIPLLFFMAASS
                     HGGLAG"
     gene            3656..4747
                     /gene="serC"
                     /locus_tag="P5537_14855"
     CDS             3656..4747
                     /gene="serC"
                     /locus_tag="P5537_14855"
                     /EC_number="2.6.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0004648 -
                     O-phospho-L-serine:2-oxoglutarate aminotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006564 - L-serine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoserine/phosphohydroxythreonine
                     transaminase"
                     /protein_id="HRV79368.1"
                     /translation="MNPATAWNFAAGPARLPDAVLERARDSLFARGADGASALERPFT
                     GDAFRATLHSARERLAQLLELPAGYRILFLAGGAMHQFALVPMNLLGGARRAAYADSG
                     YWAQRAIAEARRYCEAVAAPGFAGDAPLAAPPAGRWDLPADCAYCHITPNETVDGLAY
                     PALPDTGDIPLVADATSCLLTAPLDVARFGLLYASAQKNLGVAGLCVLVVREDLLERA
                     APAVPAALNYRRQAEADSCLNTPPTLAIHLAGLVFEWIAEAGGLAAMGAANRRKAATL
                     YAAIDGSGGFYRAPVAAAHRSPVNVRFHLADDALTEPFLAAAASRGLHHLRGHRQVGG
                     LRASLYNAMPQAGADALADFMAEFARAHA"
     gene            4819..5550
                     /locus_tag="P5537_14860"
     CDS             4819..5550
                     /locus_tag="P5537_14860"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79369.1"
                     /translation="MSKSSFPWHARPGLAGGIDKDGTRAAELLGLGFGSVEFGTVAVG
                     PRAGAELAALRARLAALPPRAPGAIGIGLGQPADAAPRALAACWIAGLYGAWDVADYL
                     SFNLSARACAPLLAPARLALVTDALRAVAAARAGLPRRVPLALKFRLGGADEAPPAVA
                     LAAAAAGFDLLTAVLPDDDPKRLSRLHALITAVSDGPAVVAVGGIRKASDVAELRASG
                     AAGVQVHRAFSESGATCLAQLLGSV"
     gene            5780..6025
                     /locus_tag="P5537_14865"
     CDS             5780..6025
                     /locus_tag="P5537_14865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004327583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stability protein"
                     /protein_id="HRV79370.1"
                     /translation="MPTTLTLKNIPDEIYQRLKASAVTHRRSLNSEAIVCLETVLLPG
                     RIDPSERLARARALRAALAESKFRAHDIDALKREGRL"
     gene            6031..6417
                     /locus_tag="P5537_14870"
     CDS             6031..6417
                     /locus_tag="P5537_14870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004327581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family
                     toxin"
                     /protein_id="HRV79371.1"
                     /translation="MDTNVLAYLYLPTEFTPHAEALLERDPEWVAPVLWRSEFRSILA
                     GYLRRKILAFDDARALQAEAESLLAGNEHEVDSQRVLELVRDTDCSAYDCEFAALAMR
                     LDVKLVTMDAKLLRAFPKFAVPLTAA"
     gene            complement(6531..7046)
                     /locus_tag="P5537_14875"
     CDS             complement(6531..7046)
                     /locus_tag="P5537_14875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004327579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HRV79372.1"
                     /translation="MSVVASPVSSTSLAADDRKLHRHPGVLIRFAPADAERILDHLVA
                     LDVDDRFLRFGYGIGDEGIARYVARIDFARDHVHGLTDAGGRVVALAHIAARDGEVDF
                     GLSVVPAWRRRGLGRALFAHVVELAALLRARRVLCHSISPAVLHMAAACGFRRAGGNP
                     AAPLVLDIPFG"
     regulatory      complement(7203..7410)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            7818..>8017
                     /locus_tag="P5537_14880"
     CDS             7818..>8017
                     /locus_tag="P5537_14880"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79373.1"
                     /translation="MPKTFKSLALVSLLTAAAGANAAALDLSGWSPLTLTYTGGQPAG
                     NWVLESGNTAVKQTVNADPSFYL"
BASE COUNT         1181 a         3009 c         2690 g         1137 t
ORIGIN      
        1 tggccgcgac ctgtcgccca gcctgctcca aatcgatcca ccgttggccc ttgtctgcgg
       61 cgccgaccac gtcgcggccg cgctccaggt cctctcgcga ctgccgtccg aaccgggcga
      121 atgatttcaa tgtagcccat cgggcgcccg gttaccgggg cggcgaaacg cagcccccag
      181 ccctctcacg tcatgatttt cgcgagccct cattcgcgat tcccggctgg ccggcgccac
      241 atccgccgga gaacaatgcg tcaaggggtc gcacggtgcg gccccgtcac acgaggagag
      301 ctccatgacc tgggaaaccc ccgcctactg cgaaatccgt ctcggcttcg aagtcacggc
      361 ctacgtgtac gtacgctgag cgtgcgctga ccgcagcagc ggcggagacg gttcgccacc
      421 gcctccgccg ctgccgccga cgctaccgac cgccatggat accgccaccc tgcccgccga
      481 cgcccgcccg cggctgtcgc cccactatgt cttccgctgg gaagagagcc agtcggcttt
      541 catcctgctg tacccggaag gcctgatcaa actcaaccct tcggccggag ccgtgctcga
      601 gcgctgcgac ggtgcgcgca cggtcgcggc gatcgtcgcc gagctgcagg cggcctttcc
      661 cgcacaggcc gcggagatcg ccgacggcgt gcgcgccttc gtggatctgg cctgcgacaa
      721 gggctggctg cgcgcggcct gatggacgcc gccccggcgc ttccggccgg cgcccccccg
      781 gccggcgcgt cgccgctgtt cgccggggcg gcgccgttcg ccacccaccg cctcgcggtg
      841 ggggacggcc acgtgctgca cgtggaggaa tgcggccgcg ccgacggcat cgcagtggtc
      901 ttcctgcacg gcggcccggg cagcggctgt agcccgcgcc agcgccggct gttcgacccc
      961 gcgcgctttc gcgccgtgct cttcgagcag cgcggcgccg gccgcagcac gccgtcgggc
     1021 ggcttgcgcg ccaacaccac cgcccacctc gtcgccgaca tcgagcgcat ccgcgcggcg
     1081 ctggcgatcg agcgctggat cgtgttcggc ggctcctggg gcagcctgct cgcgctcgaa
     1141 tacgcctgcg cgcatccgga ccgcgtcgcc ggcctagtgc tgcgcggcat cttcctcgca
     1201 tcggcagccg agctgcgcgc ctacgtcggg cgcatcccgc cgcaggcccc ggggctgcgc
     1261 gaaagcctcg agcgggaggc gcgcatccgc ctgccgcgga tgcgatcgcc gcaggccgag
     1321 gacgatctgc tcgccgcctg gtgccggtgc acgctcgccg gccgccccgc gacccagcgc
     1381 gccgccgcgc gccactggct ggaccacgag cgcgcgctga tgggcgagcc gcccctcccg
     1441 gggccgcccg acgcccgcga gctggccaag gcgcgcatcc aggcgcatta cctcgcccac
     1501 ggctgcttca ccgacgccgc gcgcctgctc gccgcctgcg ccgcgctgcg ccacctgccg
     1561 gcggcgatcg tgcacggcgc cgacgacccg gtgtgcccgc ccgccaccgc gcgcgcgctg
     1621 caccgcgccc tgcccgaggc ggactacgtc gagatccccg gcgcgggtca tgcgggactc
     1681 gcgccggaaa tggccgccgc ctgcatcacg gcgctcgacc gcgtcgccac ccgcgcccac
     1741 cccggccacg cagccggcca caccgccctc cacgccgccc aacgcgcccg ctagagaaaa
     1801 tcgccagccc gcatcgcaga gcatcaggac gccacggctg cgcccgcgcg gcaacatgac
     1861 cccatcgaca gcggaggaca cgcgccatgc caaaagaaac ccacggactc agcctcgacg
     1921 gccagggcaa gcccctgtgg ctgtcgctgg agctcaccta ccgctgcccg ctcaaatgca
     1981 cctggtgcaa caacccgctc gacttcgagg actacgccgc gaaggagctg tcgaccgagg
     2041 agtggaagca ggtgctgcgc gatgcacgcg agatcggcgc gctgcagctc ggcttcaccg
     2101 gcggcgagcc actgcagcgc gccgacctcg aggagctggt cgcctgtgcc gacgggctgg
     2161 gcttctacac caacctgatc acctcgggca tcggcctgaa cgaggagcgc ctgctcgccc
     2221 tcaaggccgc cggcctcaag cagatccagc tctcgctgca atcgacgcgc gccgacatga
     2281 ccgacgcgct ggtcggggcg cgcgcccacg cgcacaagct cgaggcggcg cgcctgatca
     2341 aggcgcacgg cttcccgatg gtgctcaaca tgccggtgtt ccgccacaac atcgagctga
     2401 tcggcgagat gatcgagtgg gccgccgggc tcggcgtcga gtacatcgag ttcgccaaca
     2461 tccagtacta caactgggcg ctgctgaacc gcgacgagct gatgcccacg ctcgagcagg
     2521 tgcgcgaggc cgagcgcgtg gtcaatgaat ggcgcgccag gctcggcaag gcgatgacga
     2581 tctacttcgt gatccccgac tactacgagg gccgccccaa ggcgtgcatg aacggctggg
     2641 gcgccatcca cctcaccatc gcgcccgatg gcgtcgccat gccctgccag gaggcgcggg
     2701 tgatccccgg gctggagttc gagtcggtgc gcgaccagcc gctcggctgg atctggcacg
     2761 agtcgccgct gttccgcaag taccgcggcc tggactggct gcccgagccc tgcgggtcct
     2821 gttccgagaa ggagaaggac ttcggcggct gccgctgcca ggccttcctg ctcaccggcg
     2881 acgccgccaa caccgacccg gcgtgcagcc gctcgccgca ccaccacctg gtgcagcagg
     2941 cggtggccgg ggtggtggcg ccgctgcgct ttcgcaagcc gctcatcaag cgcgccgccg
     3001 gcgcggtctc caccgccttc atggagggct gaatgcgcca tccctacgac accgccaccg
     3061 gcacgatcgc gctcgggctg ctgctcaccg ccgtgctcgc cgccctgctg ccgctcgtcg
     3121 ccggctgaaa gcgccatgga cccgctcctc gacctcgcgc tgcgctggac gcacttcatc
     3181 gccgggatta tctgggtcgg ccacaactac tccagcgtgg tgcagcgccc gggctggcgg
     3241 ccgctcgccg ccgccgacct caccgacgac accagcccgc gcttccaggc cctgctcaac
     3301 cgcgagcacg gcttcttccg ctgggcctcg gtggtggcgt ggagcgccgg cctgctgatg
     3361 ctgtggcagc gcggctggct gaccggcgcg ctcacgctcg acggcgcgct ggcgccgatc
     3421 gggctgggca cctggatcgg caccctgatg atgctcaacg tctggttcgt gctgtggccg
     3481 caccagcaga aggtgctcgg cctggtgccg gcgagcgtgg acgagcgcct gcgctgctcg
     3541 cgcatcaccc acctgtcctc gcgcaccaac accatgctgt cgatcccgct gctgttcttc
     3601 atggccgcga gcagccacgg cgggctggcg ggctgaacgc gagggcttac gagcgatgaa
     3661 ccccgcgacc gcctggaact tcgccgccgg cccggcacgc ctgcccgacg cggtgctcga
     3721 gcgcgcgcgc gacagcctgt tcgcgcgcgg cgcggacggc gcctcggcgc tcgagcgccc
     3781 cttcaccggc gacgccttcc gcgcgacgct gcacagcgcg cgcgagcgcc tcgcgcagct
     3841 cctcgagctg cccgccggct accgcatcct cttcctcgcc ggcggcgcca tgcatcagtt
     3901 cgcgctggtg ccgatgaacc tgctcggcgg cgcgcgccgc gcggcctacg ccgactccgg
     3961 ctactgggcg cagcgcgcga tcgccgaggc gcgccgctac tgcgaggcgg tcgccgcacc
     4021 cggcttcgcg ggcgacgcgc cgctcgccgc gccgccggcc gggcgctggg atttgcccgc
     4081 cgactgcgcc tactgccaca tcacccccaa cgagacggtc gacggcctcg cctacccggc
     4141 cctgcccgac accggcgaca tcccgctggt ggccgacgcc acctcgtgcc tgctcaccgc
     4201 gccgctcgac gtcgcccgct tcggcctgct ctacgccagc gcgcagaaga acctcggcgt
     4261 cgccgggctg tgcgtgctgg tggtgcgcga ggacctgctc gaacgcgccg cgcccgcggt
     4321 gcccgcggcg ctcaactacc gccgccaggc cgaggccgac agctgcctca atacgccgcc
     4381 gacgctggcg atccacctcg ccggcctggt cttcgagtgg atcgccgaag ccggcgggct
     4441 cgccgcgatg ggcgccgcca accgccgcaa ggccgccacg ctgtacgcgg cgatcgacgg
     4501 cagcggcggc ttctaccgcg ctccggtggc cgccgcgcac cgctcgccgg tcaatgtccg
     4561 cttccatctc gccgacgacg ccctcaccga gcccttcctc gccgcggccg cgtcccgagg
     4621 cctgcaccac ctgcgcggcc atcgccaggt cggcgggctg cgcgccagcc tctacaacgc
     4681 catgccgcag gccggcgccg acgcgctcgc cgatttcatg gcggagttcg cccgagccca
     4741 cgcatgagcg cgaccgcgca aagggacgtg cccacctcca ccggggaggt ggccgtgcag
     4801 cgatcggagg gctcggcgat gagcaagtcg tccttcccct ggcacgcccg cccgggcctg
     4861 gcgggcggca tcgacaagga cggcacccgc gccgcggagc tgctcggcct cggcttcggc
     4921 agcgtggagt tcggcaccgt cgcggtcggg ccgcgggcgg gcgcggagct ggccgcgctg
     4981 cgcgcccggc tcgccgccct gcccccgcgc gcgcccggcg cgatcggcat cggcctcggc
     5041 cagcccgcgg acgcagcgcc cagggcgctc gccgcgtgct ggatcgccgg gctctatggc
     5101 gcctgggacg tggcggacta cctgagcttc aacctgtccg cgcgcgcctg cgcgccgctg
     5161 ctggcgcccg caaggctggc gctcgtcacg gacgcgctgc gcgcggtggc ggcagcgcgc
     5221 gccggactgc cgcgccgggt tccgctcgcg ctcaagttca ggctcggcgg ggcggacgag
     5281 gcgccgccgg cggtcgcgct agccgcagcg gcggcgggct tcgacctgct cacggccgtg
     5341 ctgccggacg acgacccgaa gcgcctctcg cgcctgcacg cactgatcac cgcagtgtcc
     5401 gacggtccgg ccgtggtggc agtgggcggc atccgcaagg caagcgacgt cgccgaactc
     5461 cgcgcgagcg gcgccgccgg cgtgcaggtc caccgcgcat tctccgaatc gggggcgacc
     5521 tgtctggcgc agctgctggg cagcgtctag caacctggcg gaccatccat ttgcaaagtg
     5581 acgcgtcgcc cctgtagccc gagcgcatgg agccgctttc gtccgatcga tcgccagacg
     5641 gcgtacctcc gccaccatcg gtgcaggact ggctgcccga accgcacctg gcgcgcgatg
     5701 tggtcgatat ggtggagaca tcagcttgac gcaccggctt cagggaacca ttatggttcc
     5761 actttggaag gagcttgcga tgcccactac gctgaccctg aagaatattc cggatgagat
     5821 ataccagcgt ctgaaggcgt cggcggtaac gcacaggcgc agcctgaaca gcgaggcgat
     5881 cgtgtgcctg gaaaccgtgt tactgccggg caggatcgat ccgagtgagc gactggcccg
     5941 tgcccgcgca ttgcgggctg ctctcgcaga gtcgaagttc agggcgcacg acattgacgc
     6001 cttgaagcgc gagggccgac tgtgatcgtg gtggatacca acgtcctggc gtacctgtac
     6061 ctgccgaccg agttcactcc acacgccgag gcgctgctcg agcgtgatcc ggagtgggtg
     6121 gcgccagtgc tgtggcgcag cgagttccgc agcattctcg cgggctacct gcgacgaaag
     6181 atcctggctt tcgatgatgc acgcgccttg caggccgagg cggagagcct gcttgcgggc
     6241 aacgagcatg aagtcgactc gcagcgggtt ctggaactcg tgcgcgacac cgattgttcc
     6301 gcgtatgact gcgagttcgc ggcgctggcc atgcgcctgg acgtgaaact ggtgacgatg
     6361 gacgccaagc tgctcagggc gttcccgaag ttcgcggtgc cgctcactgc ggcgtgagcc
     6421 ctggattcag cggtttggcg cagcttcccg ctgaagctcc gccgaaatgg cttccgtcgc
     6481 gtcgccggag ccgggtgaaa acccggtcga gtgcgccggt agccgagaca tcagccgaat
     6541 gggatgtcca gcaccagggg cgccgccgga ttgccgcccg cgcggcgaaa gccgcaggcg
     6601 gcggccatgt gcagcaccgc ggggctgatg ctgtggcaca gcacgcgccg cgcgcgtagc
     6661 agcgctgcga gctcgacgac gtgggcgaac agggcccggc ccaagccgcg gcggcgccag
     6721 gcgggcacca cgctgagacc gaaatcgacc tcaccgtcac gggcggcgat gtgcgcgagc
     6781 gccacgaccc gtccgcccgc gtcggtcagg ccgtggacgt ggtcgcgcgc gaagtcgatg
     6841 cgggcgacgt agcgagcgat gccctcgtca ccgatgccgt agccgaagcg gaggaagcga
     6901 tcatcgacat cgagcgccac gaggtggtcg aggatgcgct cggcatccgc cggtgcgaac
     6961 cggatcagca caccggggtg acggtgcagc ttgcgatcgt ccgcggcgag ggacgtggag
     7021 gagacaggac tggcgacgac ggacatggcg gagaccccgg acaggcgggc gggatctccg
     7081 gcggacgcgt ccgagcctcc ccagcgccgc gaaggacgca gggacctgcc ggatcatctg
     7141 cgagacgagc aagtgaaatg gtatggacca tgcctcttgt cagggacacc ccgccctaaa
     7201 cgaatgaagg tgatgtccat ggcaggtctc ctggcttgcg ggtcatcgcc tcgtgccagc
     7261 cttcccggag agactccagt ggccagatgg gcacgcgact cgtcgcatac agttgcgggg
     7321 gcagctccgg attgcacgcg cgggcgtgtt accggattcc cttttcatgc cggccggtga
     7381 gggcaggcaa ccatgaaacg ccgcggaggt tagccgcggg cctccagcct gtcaaaccgg
     7441 gaccgtcgca ccgggaccgc cggccaaaag atatcacccg atgcgagggc ctgctcgctc
     7501 accgggaaag cccgcgactc gcccccgctc ctctacgtag gtacgccgcg cccgtgacgg
     7561 attcaggttg cgcgccgcac gggcgccgaa gtgtcggaag ttcttacacc tctcgcccac
     7621 ccactcccga acacttggac gacagcgacg aaaaccgttc tcaagccatt gaaaaatcga
     7681 cgttcatcca ttcctttcgt gatcttggcg cgagacttgc tcgcatctgt acggcgccga
     7741 ttagagacca cgcaccggcg atcgcgccgg ctatcttcga cgcgtgtcga ctcaccgtac
     7801 caatcaggag caaggacatg ccaaagacct tcaaatcact cgcgctcgtg agcctgctca
     7861 ccgccgccgc cggagcaaac gccgctgcgc tcgacctgtc gggctggtcg ccactgaccc
     7921 tcacctacac tggcggccag ccggcaggca actgggtcct cgaatccggc aacactgccg
     7981 tcaagcaaac cgtcaacgcc gacccctcgt tctatct
//
LOCUS       DAOTIN010000142         8005 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_10855_length_8005_cov_6.906415, whole genome shotgun sequence.
ACCESSION   DAOTIN010000142 DAOTIN010000000
VERSION     DAOTIN010000142.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 8005)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 8005)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8005
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_10855_length_8005_cov_6.906415"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1017
                     /locus_tag="P5537_14885"
     CDS             <1..1017
                     /locus_tag="P5537_14885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HRV79374.1"
                     /translation="RPFGGFSAVGWGAACRRVFASPGPLYEPEGARPDYYRLARALFA
                     AGFRAGDLVHNTFSYHFTPAGSMMETAAHALGCTVFPAGVGQTEQQLAAIADLQPNAY
                     VGTPSFLRILLDKADELGVSVSFTKAFVSGEAFPPSVREAFGARGIQAFQAYATADIG
                     LIAYETPAREGMVVDEDILLEIVRPGTGDPVAPGEVGEVVVTTFNPDYPLIRFGTGDL
                     SAVLLGASPCGRTNVRIKGWMGRADQTTKVKGMFVHPGQIAQVVRRHPEITRARLVVD
                     NPELNDRMTLMCEVAGGGSEALAEAITASIRELTKLRGEVAFLPAGALANDGKVIDDV
                     RTYA"
     gene            1096..2286
                     /locus_tag="P5537_14890"
     CDS             1096..2286
                     /locus_tag="P5537_14890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CaiB/BaiF CoA-transferase family protein"
                     /protein_id="HRV79375.1"
                     /translation="MNPASKAPARAPLVGVRILDLTRLLPGPLATQHLADYGAEVIKV
                     EDTGAGDYARSMGAMGGETSWFYQLVNRNKRSLRLDLKQEAGRELFLRLVEGADVVVE
                     GFRPGVMERLGLGYTTLAERNPRVVLCSISGYGQTGPYALRAGHDINYLGYAGVLDQI
                     GCAGGAPALSNLQIGDLLGGTMGAVMGILVALFDARRSGHGREVDVSMTDASFAHMIF
                     PLAEVLAHGGVRPRGEDLLSGGVPCYGVYETADGRYMAVGALEEKFWVLMCTTLGRAD
                     LIPGHLATGEEGARVRAELAAIFRGRSQREWVAVFDAVDCCVTPVLRLEESLRDPQLR
                     ARGMVVEANGLCHAGPAVRLGGMPEMPAAPAPARAGADTDAILEALGVDAGERARLRG
                     AGVI"
     gene            complement(2437..2868)
                     /locus_tag="P5537_14895"
     CDS             complement(2437..2868)
                     /locus_tag="P5537_14895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79376.1"
                     /translation="MSNDQNAQDPLEFVRGMWNQMGFSLPGMVTPTLDVDELDKRITD
                     MRAVEGWLKMNLNMLQMSIQGLEMQRAALAAVKAMSQQAQQAGEGAPAADAGANPFAA
                     AAAMWPWNLMGGQPAATPAPAAQAEAKDSARGGRRKPTTDK"
     gene            complement(2908..4812)
                     /locus_tag="P5537_14900"
     CDS             complement(2908..4812)
                     /locus_tag="P5537_14900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HRV79377.1"
                     /translation="MIHRWGIRARVTLVAFIPMLALAALMTATHTTLRLGELDNALRA
                     RAQAYVRQTAVASEYPLFIGDRIALQQLLDSLLLEEDVAAIALVAPDGSLFAQAGSFD
                     ESAPIQAAVQGTQSTRARLRIVEPIRPHPLPLDASSPDAWPEEQALATLVMEMSLARL
                     DQRRAELLWIAAGWMLMVAIGSLALARRMSHSVSGPIRNIADTVLRIGRGELDRRVPV
                     VGGGTLRVLAEGVNEMAGRLSAAHASMSRQIEDATAELRARRDEAERASVAKSRFLAA
                     ASHDLRQPLHALGLFVSELSQRKLDARSRQLVERITASAETMDGLLGSLLDISRLDSG
                     ALIPVREAFDLRMHIERIVDGHSAIAAERGLDLHLHCPPCHAHTDPLLLDRILANLLS
                     NAIRHTPRGRVLVACRRRGGRLRVEVRDSGPGIARDSQELIFHEFVQLDNPERGQDKG
                     LGLGLAIVRRLSKLLELPLELRSRPGRGSVFAVEVPAADAEQRARSRVPGSLEGVRVL
                     LADADPDTFAATAGLLSEWGCEVVAMAPTPTNDPAPADADLLILAPPSADRSGGFDTL
                     ARLRARTGLADVPAVLMADDTGDESRESARATNTHLLARPLRPSRLRALLNRLFGADD
                     GDGAQRSGIG"
     gene            5055..5681
                     /locus_tag="P5537_14905"
     CDS             5055..5681
                     /locus_tag="P5537_14905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HRV79378.1"
                     /translation="MTKILIVEDHALVREAMAQRLACLEPELVCLESAGADEALALLE
                     LHGDVDLAIVDLMLPGANGFALLGVLAKRHPDLPAIVVSAMDDDASVRRALAAGASGF
                     VSKASSGEVLALAVREVLEGGMPTPRASPPGRGGRSRSAAERYGLTSAQNRVAELLAT
                     GGSNREIAAKLGLTEGTVKVHMTAIYRALGVSSRSQALVLLSRRNRGV"
     gene            complement(5694..6398)
                     /locus_tag="P5537_14910"
     CDS             complement(5694..6398)
                     /locus_tag="P5537_14910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79379.1"
                     /translation="MAEIICVIGNKGGTGKTTLSHMLCQGLGLLGQRAACVLTDTSRE
                     PLIPAGRRYVLADARTRDSLTKVVDKLRTLENWIGVIDGGGNRTEMDRKLYALSDLVL
                     LPFRESHEDIRTVLRDLKMFPRAYAIPTQWPTNPWQRDAADRSVARLLGAHRHRILRP
                     VNALSSTKLLLQKQLPEQLPTPLANACRAVARQLLEVLEIDFIDQDEEHIGEGQEERL
                     SAAEMPLRLGGVRRPH"
     gene            complement(6498..7253)
                     /locus_tag="P5537_14915"
     CDS             complement(6498..7253)
                     /locus_tag="P5537_14915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004332402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HRV79380.1"
                     /translation="MPPALKALVAQLAGLAAAVALARSGTLAGLWPLVGAQALVAAGV
                     AAGLRSARWWLPIHLGFLPLVVIAHGAALHPGWYLGGFVVLVLVYWTSFRTQVPLYLS
                     NRATAAAVAELLPEGPARMLDIGAGTGALLRPLAQARPDCRFTGIELAPATWAIGRLL
                     LRGHANVEWLRGDLFSPDWSGYDLVYAFLSPVPMPAVWAKASTEMRPGSMLVSNGFEV
                     PGHEADAVIEVGDRRGTRLLLYRMGVRSRGRSG"
     gene            7457..7541
                     /locus_tag="P5537_14920"
     tRNA            7457..7541
                     /locus_tag="P5537_14920"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7491..7493,aa:Tyr,seq:gta)
     gene            7655..7728
                     /locus_tag="P5537_14925"
     tRNA            7655..7728
                     /locus_tag="P5537_14925"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7687..7689,aa:Gly,seq:tcc)
     gene            7759..7833
                     /locus_tag="P5537_14930"
     tRNA            7759..7833
                     /locus_tag="P5537_14930"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7791..7793,aa:Thr,seq:ggt)
     gene            7918..>8005
                     /locus_tag="P5537_14935"
     CDS             7918..>8005
                     /locus_tag="P5537_14935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012081251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HRV79381.1"
                     /translation="MAKGKFERTKPHVNVGTIGHVDHGKTTLT"
BASE COUNT         1153 a         2643 c         2972 g         1237 t
ORIGIN      
        1 cgccccttcg gcggcttctc ggcggtgggc tggggcgcgg cgtgccggcg ggtgttcgcc
       61 tcgcccggcc cgctctacga accggaaggt gcgcggcccg actactatcg cctggcgcgc
      121 gcgctcttcg ccgcgggttt tcgcgccggc gacctggtgc acaacacctt ctcctatcac
      181 ttcacccccg ccggctcgat gatggagacc gccgcgcacg cgctcggctg caccgtcttt
      241 cccgccggcg tcggccagac cgagcagcag ctcgcggcga tcgccgacct gcagcccaac
      301 gcctacgtcg gcacgccgtc cttcctgcgc atcctgctcg acaaggcgga cgagctcggc
      361 gtgagcgtgt ccttcaccaa ggccttcgtc tccggcgagg ccttcccgcc cagcgtgcgc
      421 gaggccttcg gcgcgcgtgg catccaagct tttcaggcct acgccacggc cgacatcggc
      481 ctcattgcct acgagacccc ggcgcgcgag ggcatggtgg tggatgagga catcctgctc
      541 gagatcgtcc gccccggcac cggcgacccg gtggcgccgg gcgaggtcgg cgaggtcgtg
      601 gtcaccacct tcaacccgga ctacccgctg atccgcttcg gcaccggcga cctttccgcg
      661 gtgctgctcg gcgcctcgcc ttgcgggcgc accaacgtgc gcatcaaggg ctggatgggg
      721 cgcgccgacc agaccaccaa ggtcaagggc atgttcgtgc atccgggaca gatcgcccag
      781 gtcgtgcgcc gccaccccga gatcacgcgt gcgcgcctgg tggtcgacaa ccccgagctc
      841 aacgaccgca tgacgctgat gtgcgaggtc gccggtggcg gcagcgaggc gctcgccgag
      901 gcgatcacgg cgagcatccg cgaactgacc aagctgcgcg gcgaggtcgc cttcctgccc
      961 gcgggcgcgc ttgccaacga cggcaaggtc atcgacgacg tgcgtaccta cgcgtagctg
     1021 cgagcccgtc gcccgcgtgc tccggcggcg ggggctggca tactgccgcc tttccgcaac
     1081 acgatggacg cgcacatgaa ccccgcatcg aaagctcccg cacgcgcgcc gctcgtcggc
     1141 gtgcgcatcc tcgacctcac gcggctcctc cccggtccgc tcgccaccca gcacttggcc
     1201 gactacggcg ccgaggtgat caaggtggag gacaccggcg ccggcgatta cgcgcgcagc
     1261 atgggtgcga tgggggggga gacgagctgg ttctaccagc tggtcaaccg caacaagcgc
     1321 agcctgcgcc tggacctcaa gcaggaggcg ggacgcgagc tcttcctgcg cctggtggag
     1381 ggcgccgacg tggtggtcga gggcttccgc cccggggtga tggagcgcct gggcttgggc
     1441 tataccacgc tcgcggagcg caatccgcgc gtggtgctgt gcagcatcag cggctacggg
     1501 cagaccgggc cgtacgcgct gcgcgccggc cacgacatca actacctcgg ctatgcgggc
     1561 gtgctcgacc agatcggctg cgcgggtggt gcgccggcgc tgtcgaacct gcagatcggc
     1621 gacctgctcg gcggcaccat gggggcggtg atgggcatcc tggtggcctt gttcgacgcg
     1681 cgccgcagcg gccatggtcg cgaggtggac gtgtcgatga ccgatgccag cttcgcgcac
     1741 atgatcttcc cgctcgccga ggtgctcgcc catgggggcg tgcggccgcg cggcgaggac
     1801 ctgctgtccg gcggcgtgcc ctgctacggc gtgtacgaga ccgcggacgg ccgctacatg
     1861 gcggtgggtg cgctggagga gaagttctgg gtgctgatgt gcaccacgct cgggcgcgcc
     1921 gacctgatcc cggggcatct cgccaccggg gaggagggcg cgcgggtgcg cgccgagctc
     1981 gcggccatct tccgcggccg tagccagcgc gagtgggtgg cggtgttcga cgcggtcgat
     2041 tgctgcgtga cgccggtctt gcgcctggag gagagcctgc gcgacccgca gctgcgcgcg
     2101 cgcggcatgg tggtggaggc gaacggcctg tgccacgccg gcccggcggt gcgcctgggc
     2161 ggaatgccgg agatgcctgc cgcgccggcc ccggctcgcg cgggggcgga cacggacgcg
     2221 atcctggagg cgctcggggt ggacgccgga gaacgtgcgc ggctgcgcgg cgcgggggtg
     2281 atctagggta ggggtcgccc tggcctgcgc gatgagccga cgcctcccgg cagtcgccgg
     2341 gtggacgaaa ggcacacgcg ctgatgcccg cacgcagcgg caggaaagcg agcccgcgat
     2401 gcgggccatg ccgggcgggc gggtgcggcg cgcggattac ttgtcggtgg tcggcttgcg
     2461 gcgcccgccg cgcgcgctgt ccttggcttc ggcctgcgct gcgggtgccg gcgtggcagc
     2521 gggctgcccg cccatgaggt tccacggcca catcgccgcc gcagctgcga acgggttggc
     2581 gccggcatct gccgcggggg cgccttcgcc cgcctgctga gcctgctggc tcatcgcctt
     2641 gaccgcggcg agcgcggcac gctgcatctc cagcccctgg atgctcatct gcagcatgtt
     2701 caggttcatc ttgagccagc cttcgaccgc gcgcatgtcg gtgatgcgct tgtccagctc
     2761 gtcgacgtcg agcgtgggcg tgaccatgcc cggcagcgag aaacccatct ggttccacat
     2821 gccgcgcaca aactcgagcg gatcctgggc gttctggtca ttggacatcg ggctgctccg
     2881 gtcgggggtt gagttgatgg aaggatatta accgatgccg ctgcgctgtg cgccatcgcc
     2941 gtcgtcggcc ccgaagagcc ggttcagcag ggcgcgcaga cgggagggac gcagcgggcg
     3001 ggcgagaaga tgcgtgttcg tggcgcgcgc gctttcgcgc gattcgtcgc cggtgtcgtc
     3061 ggccatcagc acggcaggca cgtccgccag cccggtacgg gcgcgcagtc gggcgagggt
     3121 gtcgaagccg ccggagcggt ccgcggacgg cggcgcgagg atcagcaggt cggcgtccgc
     3181 cggtgccggg tcgttcgtcg gggtcggtgc catggcgacg acctcgcagc cccactcgga
     3241 gagcaggccg gcggtcgccg cgaaggtgtc ggggtccgcg tcggcgagca gcacgcgcac
     3301 cccctcgagg ctgcccggaa cccggctccg tgcgcgctgc tccgcatcgg cggcgggaac
     3361 ttcgaccgcg aacaccgagc ctcgtccggg ccgcgaacgc agctcgagcg gcaactcgag
     3421 cagcttgctc aggcggcgca cgatcgccag ccccagcccc agccccttgt cctggccgcg
     3481 ctccggattg tcgagctgga cgaactcgtg aaagatcagt tcctgcgaat cgcgggcgat
     3541 cccggggccg ctgtcccgca cttccacgcg cagcctgcca ccgcgtcgcc gacaggcgac
     3601 cagcacgcgg ccgcgcgggg tgtggcggat ggcgttggag agcaggtttg cgaggatgcg
     3661 gtcgaggagg agcgggtcgg tgtgggcgtg gcagggcggg cagtgcaggt gcaggtcgag
     3721 gccgcgttcg gcggcgatgg cggagtggcc atccacgatg cgctcgatgt gcatgcgcag
     3781 gtcgaaggcc tcccgcaccg ggatgagcgc gccggagtcg aggcgcgaga tgtcgagaag
     3841 gctgccgagc agcccgtcca tggtctcggc ggaggcggtg atgcgttcga cgagctggcg
     3901 gctgcgcgcg tcgagcttgc gctgcgagag ctccgacacg aacagcccga gcgcgtgcag
     3961 cggctggcgc aggtcgtggc tggccgcggc gaggaagcgc gacttcgcga cgctggcccg
     4021 ctcggcctcg tcgcgacgcg cgcgcagctc ggcggtggcg tcctcgatct ggcgcgacat
     4081 cgaagcgtgc gcggcgctca ggcgcccggc catctcgttc acgccttcgg cgagcacacg
     4141 cagggtgccg ccgccgacca ccggcacgcg gcggtcgagc tcgccgcgac cgatgcgcaa
     4201 cacggtgtcg gcgatgttgc ggatggggcc gctgacgctg tggctcatcc ggcgcgcgag
     4261 cgcgaggctg ccgatggcga ccatcagcat ccagccggca gcgatccata gcagctcggc
     4321 gcggcgctga tcgagacgtg cgagcgacat ttccatgacc agggtggcga gcgcttgctc
     4381 ctcgggccag gcgtcgggcg agcttgcgtc gagcggcagc gggtgcggac ggatcggctc
     4441 gacgatgcgc agccgtgccc gcgtcgattg cgtgccttgc acggccgcct gtataggcgc
     4501 ggactcgtcg aagctgcctg cctgggcgaa caggctgccg tccggtgcga cgagtgcgat
     4561 cgcggccacg tcttcctcga ggagcaggct gtcgagcagc tgttgaagcg cgatccggtc
     4621 cccgatgaac aaggggtatt cgctcgccac cgcggtctgg cggacgtagg cctgcgcgcg
     4681 cgcgcgcaac gcgttgtcga gttcgccgag gcggagcgtg gtgtgggtcg cagtcatcag
     4741 cgcggccagc gccagcatcg gaatgaaggc gaccagggtg acccgggcgc ggatgcccca
     4801 tcggtggatc aaggccttct cctcggcgcg gcgcgatcgg gctcggcagg gaacgggcgg
     4861 gcagacatgg cgacgactcc cgggagggtg ggacggaccg ttggcaggag attccccggc
     4921 gctggccggc ggcacggcgt cagccgtcgg aaggattttc catcgtttgt cggtgccggc
     4981 atagccggcc cgcgggcggg cgatgttccg ccggcatgcc tcgtgctatg ttcggcggga
     5041 aaaaggggga gagcatgacg aagatcctga tcgtcgaaga tcatgcgctg gtgcgcgagg
     5101 cgatggcgca gcgcctcgcg tgcctggagc cggagttggt ctgtctggag tcggcggggg
     5161 cggacgaggc cctggcgctg ctcgagttgc acggcgacgt cgatctggcg atcgtcgacc
     5221 tgatgctgcc tggtgccaac ggcttcgcgc tgctcggcgt gctcgccaaa cggcaccccg
     5281 acctgccggc gatcgtggtg tcggcgatgg acgacgacgc gtccgtgcgc cgtgcgctcg
     5341 ccgcaggggc ctcgggtttc gtctccaagg cgagttcggg cgaggtgctg gcgctcgcgg
     5401 tgcgcgaggt cctggagggg ggcatgccga ccccgcgtgc gagccctccc ggccgaggcg
     5461 gccgctcgcg ttcggcggcc gagcgctatg ggctcaccag cgcccagaac cgtgtggcgg
     5521 agttgctcgc caccggtggc agcaaccgcg agatcgcagc caagctcggc ctcaccgagg
     5581 gtacggtgaa ggtgcacatg acggcgatct accgcgcgct cggcgtgagc agccgcagtc
     5641 aggcgctggt cctgctctcg cggcgcaaca ggggggtctg agcccgcccg ggttcagtgt
     5701 ggccgccgca cgccgccaag ccgcagcggc atctccgcgg cggacaggcg ctcttcctgt
     5761 ccctcgccga tgtgctcctc gtcctggtcg atgaaatcga tctcgagaac ctcgagcagt
     5821 tggcgggcga cggcgcggca ggcgttggcg agcggggtgg gcagctgttc ggggagctgc
     5881 ttctgcagca gcagcttggt cgacgagagc gcattgaccg ggcgcaggat gcggtgacgg
     5941 tgggcgccca gcaggcgcgc cacgctgcgg tccgcggcgt cgcgctgcca ggggttggtc
     6001 ggccactgcg tgggaattgc gtaggcgcgc gggaacatct tgaggtcgcg cagcacggtt
     6061 cggatgtctt cgtgtgactc gcggaagggc agcagcacga ggtcggagag cgcatagagc
     6121 ttgcggtcca tctcggtgcg gttgccgccg ccgtcgatca cgccgatcca gttctccagc
     6181 gtgcgcagct tgtcgaccac cttggtcagc gagtcgcggg tgcgcgcgtc ggccagcaca
     6241 tagcgccgac cggcgggaat cagcggctcg cgcgaggtgt cggtgagcac gcaggcggca
     6301 cgctggccga ggaggccgag gccctggcac agcatgtgcg agagggtcgt cttgccggta
     6361 ccgcccttgt tgccgatcac gcagatgatc tcagccatga cgcttcagtc ctttgcacgc
     6421 agtccttgca tggcacggat tatcggcgcc gtgtgcaagc gcgtgagcgc ggaaaagcac
     6481 cgcttcgcgg ggtcaattca gccgcttcgg cctcgtgagc gcacgcccat gcggtaaagc
     6541 aggaggcgcg tgccacggcg gtcgccgact tcgatcaccg cgtccgcttc gtggccgggc
     6601 acttcgaagc cgttgctgac cagcatgctg cccggacgca tctcggtgct tgccttcgcc
     6661 cacaccgcgg gcatcggcac cggcgacagg aaggcgtaca ccaggtcgta gccgctccag
     6721 tcgggagaga agaggtcgcc gcgcagccat tcgacgttgg cgtggccgcg cagcagcagg
     6781 cgcccgatcg cccaggtcgc gggcgcgagc tcgatgccgg tgaagcggca gtcggggcgt
     6841 gcttgcgcga gcgggcgcag cagcgcgccg gtgcctgcgc cgatgtccag cattcgcgcc
     6901 gggccttctg gcaggagctc cgccaccgcc gctgcagtcg cgcggttgct gaggtagagc
     6961 ggaacctgcg tgcggaagct cgtccaatac accagaacga gcacgacgaa gccgccgaga
     7021 taccagcccg ggtggagggc tgcgccatgt gcgatcacga ccagcgggag aaagccgagg
     7081 tggatcggca gccaccagcg cgcgctgcgc aagccggccg ccaccccggc tgcgacgagc
     7141 gcctgcgcgc ccaccagcgg ccacagtccc gcgagggtgc cgctgcgtgc gagcgcgacc
     7201 gccgccgcaa gtccggcaag ctgggcgacg agggccttga gggcaggggg catgagcgct
     7261 cccgggaaag aagtccgaag cgctcgatca taacgcccca agtgctcgat ccgttcggtc
     7321 gaggccaagc cgagggggtg gcgtaaggag gcggccgaag gggagtcagc ggccggcagg
     7381 atcgcgcgtg gcaatttttt tacgaaaagc tttgacttct cgtgggaagg cctctatagt
     7441 gcggggcttc ccggacggag ggatacccaa gcggtcaacg ggatcagact gtaaatctga
     7501 cggctcagcc ttcgaaggtt cgaatccttc tccctccacc aagtttcagt cgtgccgcgc
     7561 ttgtcgcggt cgatgtggca aatgcagtga ctggctgcga gttgtggtga gcgcggaaat
     7621 ccgcgcaggt tggcgaacac agttgcaggc gtgtgcgggt gtagctcaat ggtagagcag
     7681 aagccttcca agcttatgac gagggttcga ttcccttcac ccgctccagc atcgctgcgc
     7741 tttgctcgag gtttcggggc ccatgtagct cagtggtaga gcactccctt ggtaagggag
     7801 aggccacgtg ttcaatccac gtcatgggca ccatccattt tctgcctggc ctgggcggcg
     7861 gccaacgagt gtggtcgccg cgccggtttt tctggttctg attttaagga tagcgatatg
     7921 gctaagggta agttcgagcg caccaagcct cacgtcaacg tcggcaccat cggccacgtc
     7981 gaccatggca agaccacgct gaccg
//
LOCUS       DAOTIN010000143         7970 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_10921_length_7970_cov_9.323942, whole genome shotgun sequence.
ACCESSION   DAOTIN010000143 DAOTIN010000000
VERSION     DAOTIN010000143.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 7970)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 7970)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7970
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_10921_length_7970_cov_9.323942"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            11..1126
                     /locus_tag="P5537_14940"
     CDS             11..1126
                     /locus_tag="P5537_14940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV79382.1"
                     /translation="MAGHALDEVFAAGAEGIRLAGDWTLRGLDERLPALRAALAAAPA
                     DARWSLRAVRRMDSFGALLLWQAWGGRWPAALEADDGQRAIIGRIERSAARALPAPAR
                     TSALDHVALLGEGLLAFGSHLAGFIALLGRFALDLGHLLRHPRDWPLLEISANLYKVG
                     VKAMPVSALVGFLVGVVLSYLSALQLRTFGADAFIVNILGMGIIRELGPVLVSVLVAG
                     RSGSAMTAQLGVMRVTEEIDALAAMGVSRGLRLVLPKVVALVLAMPLLVLWTSALALL
                     GGWVSAWVELDIGLHFFLQALPGAVPVANLYIGLAKGAVFGFLIALVACHFGLRVRPD
                     TESLSANTTASVVSAITVVILADALFAIATRSIGLPV"
     gene            1135..1914
                     /locus_tag="P5537_14945"
     CDS             1135..1914
                     /locus_tag="P5537_14945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HRV79383.1"
                     /translation="MTNAPVVRVEGIVTRFGRNVVHEGLDLSIRAGEIVALVGGSGSG
                     KTTLLRHVIGLTRPAAGRVEVFGEALDAGGAPRRLARQRRMGVLFQHGALFSAFSVAQ
                     NIAFPLRELGMMSPREIDRLVALKLEMVEMEPAHALLMPAELSGGMVKRVALARALAL
                     EPELLLLDEPTAGLDPDRSASFIRLIRALHRELGLTVVLVTHDLDTLAQMATSVAVLA
                     EGRIVSHASLEDTLALDHPFVARFFRGLQARRSHSHGAGAG"
     gene            1918..2871
                     /locus_tag="P5537_14950"
     CDS             1918..2871
                     /locus_tag="P5537_14950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MlaD family protein"
                     /protein_id="HRV79384.1"
                     /translation="MENRAHALAAGLFAIMLGAGIVFAIWWFSDQRVPMRELVLEARG
                     DINGLGEQSRVRYRGMAAGRVRAIGIDPADLRTLLVSIVVPADLPLTQGTTATLGTLG
                     VTGLAFVQLDDRGDDRRPLFAADGEAPRIALRAGLVEQLSGRALAALDQFTVLGERLA
                     RLADERTIERLQGLLASLESAAAGVDRGMTGLPATLTALRATLSAANIARISGLLANL
                     ERGSAEAAPAVAELRRLIARIDQASARLEQGVGAAGEDLVERTLPQLDALLDELTTTS
                     QRFGHLVEELDASPQLLLTGRGRPRPGPGEAGHEDFAEGDR"
     gene            2868..3527
                     /locus_tag="P5537_14955"
     CDS             2868..3527
                     /locus_tag="P5537_14955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-type transport auxiliary lipoprotein family
                     protein"
                     /protein_id="HRV79385.1"
                     /translation="MSTREEYTPPASRDGRRRLAEWAAGVAAALLLAGCQVFPERPPV
                     AATYDLGTGERGSLANALAPARVTVSAPAWLQVTAMHYRDVRGDPGRRRTYADNRWAA
                     QPPAMLALVLERALGAGEGGGCRLQVQLDEFEQLFHGGDRSEARLVARFALLPVRGGK
                     PLASAALTVLEPAPTADASGGASAFRAAAGRLADEVAQWLADTDRTLPGGLAGVGHCR
                     R"
     gene            complement(3600..5291)
                     /locus_tag="P5537_14960"
     CDS             complement(3600..5291)
                     /locus_tag="P5537_14960"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004379415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HRV79386.1"
                     /translation="MNLRTRFLLLISALIVVGSVVAWVVFHHVARQIVVQWGQRVAEI
                     QVRYDRARLLQPLEREIALARQMADSLVLKRWARSSGDPALEAEAVREMENFRRNFSS
                     GNYFVALRGSGAYYHNNAGDEFAGRQLRYHLSPAKPADAWFYKLIEVGRDFHLNVNPD
                     AELGVTKLWIDVLIRDGDEILGIVGTGIELSRFLDEIVDLHQAGVSTLFADLSGAIQL
                     HRDAKLIDFASVVKPEGQKSLVDQLLDREADRAELRETMRDLATSGDGTPRVLDRFVE
                     SAGRRILLGIAFVPEIGWYEITLLDLDVLMPVAAFTPVAVGFILTLLVALVLVHLLLR
                     RLILDPLGRLEQAMLRVRDGDLSPAPLPQTRGEIGRLTQHFDAMAGAIRAHTAELEAK
                     VRERTDALHRLARIDPLTGLTNRRGMTELLEAEITRAERQGSRFGLLWLDVDHFKEIN
                     DRRGHGVGDKALTTLARMLEGCLRPYDRGARWGGDEFLVLLSPCDGATLEAIAQRVRA
                     DIEHGSAASGETFTVTVGACLAEPGETLGTVLQRADEALYRAKQAGRNRVVIAPH"
     gene            5515..6324
                     /locus_tag="P5537_14965"
     CDS             5515..6324
                     /locus_tag="P5537_14965"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004379417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HRV79387.1"
                     /translation="MNAESSPVVETEAPILRREDAGGVTTLTLNRPQQFNALSFEMLE
                     ALIAAVDEITRDETVRVVVIAGEGKAFCAGHDLKEMRGNHTLDFQQRLFRLCGKFMMK
                     LTELPQPVIARVHSIATAAGCQLVSMCDLAVAADHARFAVSGINVGLFCATPSVGLAR
                     NMGRKEAFEMLVTGDFIDAHEAQRRGLVNRVVPADELDAEVGRLAASILSKSPAAIRM
                     GKQMFYKQLEMGLDAAYQMAAETMACNAMCEDAAEGIDAFIAKRKPEFKGR"
     gene            6353..7123
                     /locus_tag="P5537_14970"
     CDS             6353..7123
                     /locus_tag="P5537_14970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004379419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HRV79388.1"
                     /translation="MLIDSHIHLDAAEFAPDRAVVIEAARAAGVRGFVVPAVDRASCD
                     AVLALAAARADVCPALGIHPLYVMQAREDDLDRLDELLAERAARAVGEIGLDHFAVEV
                     DRERQLRFFIAQLGLARRHGLPVILHVRRAIDPILRELRRARVCGGIAHAFNGSRQQA
                     DTFIALGFRLGFGGAMSYEGSTRIRELARSLPLESIVLETDAPDIPPAWARGERNLPQ
                     NLARYARILAELRRIDVEEVIEKTGLNLMETLGGWQPH"
     gene            complement(7127..7735)
                     /locus_tag="P5537_14975"
     CDS             complement(7127..7735)
                     /locus_tag="P5537_14975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004379422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HRV79389.1"
                     /translation="MENIVKKPRTQLDRAAWVAGATEVLAEEGIAGLRVEVLAKRLKV
                     TKGSFYWHFTDRRDLLMAVLTHWKEGRIRDIIKQTRAQPGRELEQIYHVIDVYSASRS
                     RRGMMIELAVRDWARRDAEAGAIVAEVDDVRLRCARDLFLACGVPMEEASSRCMLLYA
                     YVFGVSLMIYEKFDRDVARLKRDIADLIARSCAVGTTGAAAA"
BASE COUNT         1140 a         2725 c         2816 g         1289 t
ORIGIN      
        1 ctgagcagcg atggcggggc acgcgctcga cgaggtcttc gcggccggag ccgagggcat
       61 ccgcctcgcc ggcgactgga ccctgcgcgg gctcgacgag cgacttcccg cactgcgcgc
      121 tgcgctcgcc gcggctcccg ccgatgcgcg ctggtccctg cgcgcggtgc gccgcatgga
      181 cagcttcggc gccttgctgc tttggcaggc ctggggcgga cgctggcccg ccgcgctgga
      241 ggcggacgat ggccaacgcg ccatcatcgg ccgcatcgag cgttccgccg cgcgtgcgct
      301 gcctgccccg gcgcgcacct ccgccctcga ccacgtggcg ctgctcggtg aggggctgct
      361 ggcttttggc agccaccttg ccggctttat cgcgctcctc ggccggttcg cgctcgatct
      421 cggccatttg ctccgccatc cgcgcgactg gccgctgctg gagatctcgg caaacctgta
      481 caaggtcgga gtcaaggcca tgcccgtttc ggccctggtc ggcttcctgg tcggggtggt
      541 gctgtcctac ctgtctgcgc tgcagctgcg caccttcggc gcagacgcct tcatcgtgaa
      601 tatcctcggc atgggcatca tccgcgagct cgggcctgtg ctggtgtcgg tgctggtggc
      661 ggggcgctcc ggctccgcga tgacggcgca gctcggcgtg atgcgggtga ccgaggagat
      721 cgacgcgctc gcggcgatgg gtgtttcacg cggcctgcgc ctggtcctgc ccaaggtggt
      781 cgccctggtg ctggcgatgc cgctgctggt gctatggact tcggcgctcg cgctcctcgg
      841 cgggtgggtg tccgcctggg tggagctcga tatcggcctg cacttcttcc tgcaggcctt
      901 gcccggtgcg gtgccggtcg ccaacctgta catcgggctg gccaagggtg ccgtgttcgg
      961 cttcctgatc gcgctcgtcg cctgtcattt cggcctgcgg gtgaggccgg ataccgagag
     1021 cctgtcggcc aacaccaccg cctcggtggt gtcggcgatc acggtggtga tcctggccga
     1081 cgcattgttc gcgattgcca cgcgctcgat cgggctgccg gtgtgagtgc gccgttgacg
     1141 aacgccccgg tggtacgcgt cgagggcatt gtcacccgct tcgggcgcaa tgtcgtgcac
     1201 gaggggctgg acctttccat ccgcgccggc gagatcgtcg ccctggtggg gggctcgggc
     1261 agcggcaaga ccacgctgtt gcgccacgtc atcggcctga cgcggcccgc cgcgggccgc
     1321 gtcgaggtgt tcggcgaggc cctcgacgcg ggcggggcgc ctcgacggct cgcccgccag
     1381 cgccgcatgg gcgtgctgtt ccagcatggg gcgctgttct cggccttcag cgtggcgcag
     1441 aacatcgcct ttccgctgcg tgagctgggc atgatgagcc cccgggagat cgaccgcctg
     1501 gtcgcgctca agctggagat ggtggagatg gagccggcgc atgcgctgct gatgccggcc
     1561 gagctctcgg gcgggatggt caagcgcgtg gcgctcgcac gtgcgctcgc gctcgagccc
     1621 gagttgctgc tgctcgacga gcccaccgcc gggctggacc ccgaccgcag cgcaagcttc
     1681 atccgactga tccgcgcgct gcaccgcgag ctcggtctca ccgtggtgct ggtgacccac
     1741 gatctcgata cactcgcgca gatggccacg agcgtggcgg tgctcgccga gggccgcatc
     1801 gtcagccatg cctcgctcga ggatacgctc gccctcgacc accccttcgt cgcccgcttc
     1861 ttccgcgggc tgcaggcgcg ccgcagccac tcgcacggcg caggagcagg ctgaaccatg
     1921 gaaaaccgag cccacgcgct cgccgccggg ctgttcgcaa tcatgctggg cgccggcatc
     1981 gtgttcgcga tctggtggtt ctccgaccag cgcgtaccga tgcgcgagct tgtgctcgag
     2041 gcgcgcggcg acatcaacgg actcggcgag cagtcgcgcg tacgctaccg cggcatggct
     2101 gccgggcgcg tgcgcgcgat tggcatcgac cctgcggacc tgcgtacgct gctggtgagc
     2161 atcgtcgttc cggccgacct gcccctgacg cagggcacca ccgcgacgct cggcacgctg
     2221 ggtgtgaccg gtctcgcctt cgtgcaactc gacgatcgcg gcgatgaccg caggcccttg
     2281 ttcgctgccg acggcgaggc gccgcgcatc gcgctacggg ccggcttggt ggaacagctc
     2341 tcggggcgcg cactggccgc cctcgaccaa tttacggtgc tcggcgagcg cctggcgcgt
     2401 ctcgccgacg agcgcacgat cgagcgcctg cagggtttgc tggccagcct cgagtcggcc
     2461 gcagcgggcg tggaccgcgg catgaccggg cttccggcca cactcaccgc gctgcgcgcc
     2521 acgctgagcg cagccaacat cgcccgcatc agcggccttc tcgccaatct cgagcgcggc
     2581 tcggccgaag ccgcgccggc ggtggccgaa ctgcgccgcc tgatcgcacg catcgaccag
     2641 gcgagcgcac gactggagca gggtgtgggc gctgcaggcg aggacctcgt cgagcgcacg
     2701 ctgccgcagc tcgacgccct gctcgacgag ctgaccacca cgtcgcagcg tttcggccac
     2761 ctggtcgagg agctcgacgc ctcgccgcag ctcttgctca ccgggcgggg ccgccctcgg
     2821 ccggggccgg gcgaggcagg tcacgaggat ttcgccgagg gcgacagatg agcacgcgag
     2881 aggaatacac gccgccagcg tcgcgcgatg gccgtcgtcg cttggcggaa tgggctgccg
     2941 gtgtggcagc cgcgctgctg ctcgccggct gccaggtgtt tccggagcgc ccgccggtcg
     3001 ccgcaaccta cgaccttggc accggggaac gcgggtcgct cgcgaacgca ctcgctccgg
     3061 cgagggtcac ggtgtccgcg cctgcctggc tgcaggtcac ggcgatgcat taccgcgacg
     3121 ttcgcggcga tcccggccgc cgccgcacct acgctgacaa tcgctgggcg gcgcagccgc
     3181 cggccatgct tgcgctcgtg cttgaacgcg cgctgggggc cggcgagggg ggaggttgcc
     3241 gcttgcaggt gcagctcgac gagttcgagc agctcttcca tggcggcgat cgcagcgagg
     3301 cgcgcctggt ggcgcgcttc gcgctgctgc ccgtgcgtgg gggcaagccc ttggccagcg
     3361 cggcccttac cgtgctggaa cccgcgccga cggcggacgc gagcggaggt gccagcgcct
     3421 tccgcgccgc cgctgggcga ctggcggatg aagtcgcgca gtggctggcc gataccgatc
     3481 ggacgctgcc gggcggactc gccggcgtgg gccactgccg gcgctgaggc gctcggtgcg
     3541 ggcgtggacg acgcgccgaa ggcggctccc atcgccgcgt cgcgaacacc gcatgccgat
     3601 cagtgtggag cgatcacgac ccggttacgg cccgcctgct tggcgcgata gagcgcctcg
     3661 tcggcgcgtt gcagcaccgt gcccagcgtc tcgcccggct cggccaggca ggcaccgacg
     3721 gtgaccgtga aggtctcgcc gctcgcggcg ctgccgtgct cgatgtcggc gcggacgcgc
     3781 tgcgcgatcg cctcgagcgt ggcgccgtcg catggcgaca acagcacgag gaactcgtcg
     3841 ccgccccagc gcgcgccgcg gtcatagggt cgcaggcagc cctccagcat gcgcgccagc
     3901 gtcgtgagcg ccttgtcgcc gacgccgtgt ccgcggcggt cgttgatctc cttgaagtga
     3961 tcgacgtcca gccacaacag gccgaagcgg ctgccctggc gctcggcacg ggtgatctcg
     4021 gcctccagca gctcggtcat gccgcggcga ttggtcaggc cggtgagcgg atcgatgcgc
     4081 gccaggcggt gcagggcgtc ggtgcgctcc cgcacctttg cctcgagctc ggccgtgtgc
     4141 gcgcggatcg cgcctgccat cgcgtcgaag tgctgggtca ggcggccgat ctccccgcgc
     4201 gtctgcggca gcggcgcggg gctgaggtcg ccgtcgcgta cccgcagcat ggcctgctcc
     4261 agcctgccga gcgggtcgag gatcaggcgg cgcagcagca gatggacgag gacgagcgcg
     4321 accagcaggg taaggatgaa gccgaccgcg accggggtga aggctgcgac cggcatcagc
     4381 acgtcgaggt cgagcagggt gatctcgtac cagccgatct cgggcacgaa ggcgatcccg
     4441 agcaggatcc gccgcccggc ggactcgacg aagcggtcca gcacccgcgg cgtaccatcg
     4501 ccggacgtcg ccaggtcgcg catcgtctcg cgcagctcgg cacggtcggc ttcgcggtcg
     4561 agcaactgat cgaccaggct cttctgccct tcgggtttga ccacgctggc gaaatcgatc
     4621 agcttcgcat cgcggtggag ctggatcgcg cccgagaggt cggcgaacag cgtgcttacg
     4681 ccggcctggt ggagatcgac gatctcgtcg aggaagcgcg acagctcgat gccggtgccg
     4741 acgatgccga gtatctcgtc gccgtcgcgg atcagcacgt cgatccacag cttggtgacg
     4801 ccgagctcgg cgtcgggatt gacgttgagg tgaaagtccc gcccgacctc gatgagcttg
     4861 tagaaccagg catcggctgg cttggctggg gagaggtggt agcgcagctg gcgtcctgca
     4921 aactcgtccc cggcgttgtt gtggtagtag gcgccggagc cgcgcaaggc gacaaagtag
     4981 ttgccggagc tgaaattacg gcggaagttc tccatctcgc ggacggcctc ggcttcgagc
     5041 gccggatccc cggacgagcg cgcccagcgc ttgagcacaa gcgagtcagc catctgccgt
     5101 gccagcgcga tctcacgctc gagcggctgc agcagccggg cgcggtcgta gcgcacctgg
     5161 atttcggcga cgcgctgccc ccattgcacc acgatctggc gcgccacatg atggaacacc
     5221 acccacgcca cgaccgaccc gaccacgatc agtgcggaga tgagcaggag aaaacgggtt
     5281 ctgaggttca agcgccgaca ccccctgttc gagttcttgt ccgtggctcc atattcagtt
     5341 tgggctgtcg tggggtcgaa gggtgtgcgt tttctcacac ccggatcgat gccgtcagca
     5401 ccgcggcgga ccatgccacc gtgcgaagcg ctggcgcgct gtgccggttg acgttaacgt
     5461 tgccgaccgt ggccgccaag cccagcaatc atgaatccag gaggagagag aacgatgaac
     5521 gccgagtcca gccccgtggt agaaaccgaa gcccccatcc tgcgccgaga ggatgccggc
     5581 ggcgtgacca cgctcacgct caaccgcccg caacagttca atgcgctctc gttcgagatg
     5641 ctcgaggccc tgatcgccgc ggtcgacgag atcacgcgcg acgagacggt gcgcgtggtg
     5701 gtcatcgccg gcgagggcaa ggccttctgc gccggccacg acctcaagga gatgcgcggc
     5761 aaccacacgc tcgacttcca gcagcgcctg ttccgcctgt gcgggaagtt catgatgaag
     5821 ctcaccgagc tgccgcagcc cgtgatcgcg cgcgtgcaca gcatcgccac cgccgcgggc
     5881 tgccagctgg tgtcgatgtg cgacctcgcc gtggcggcgg accacgcccg cttcgcggtg
     5941 tcgggcatca atgtcgggct gttctgcgcc acgccgagcg tcggccttgc ccgcaacatg
     6001 gggcgcaagg aggccttcga gatgctcgtc accggagact tcatcgacgc gcacgaggcg
     6061 cagcgccgcg ggctggtgaa tcgcgtggtg cccgccgacg agctcgacgc cgaggtcggc
     6121 cgcctggccg cgtccatcct gtccaagtcg cctgcggcga tccgcatggg caagcagatg
     6181 ttctacaagc agctcgagat ggggctggat gcggcctacc agatggcggc cgagaccatg
     6241 gcctgcaacg cgatgtgcga ggatgcggcc gaaggcatcg acgccttcat cgccaagcgc
     6301 aagcccgagt tcaaggggcg ctgagcgccg caagcccgcg gtcgtgccgg cgatgctgat
     6361 cgactcccac atccacctcg acgccgccga gttcgcgccc gaccgcgcgg tggtgatcga
     6421 ggccgcgcgt gctgcggggg tgcggggctt cgtcgtgccg gcggtcgatc gcgcgagctg
     6481 cgacgccgtg ctcgcgctcg ccgcggcgcg cgcggatgtc tgtccggcgc tcggcatcca
     6541 tccgctgtac gtgatgcagg cgcgggagga cgacctcgat cggctggacg agctgctcgc
     6601 cgaacgcgct gcgcgagccg tcggcgagat cggcctcgat cactttgccg tcgaggtcga
     6661 tcgcgagcgc cagttgcggt tcttcattgc gcagctcgga ctggcgcgcc gccacgggct
     6721 gcccgtgatc ctgcacgtgc ggcgcgcgat cgacccgatc ctgcgcgaac tgcgccgggc
     6781 tcgggtgtgc ggtggcatcg cccacgcctt caatggcagt cgccagcagg ccgatacctt
     6841 catcgcgctc ggcttccggc tcggttttgg cggtgcgatg agctacgagg gctcgactcg
     6901 catccgcgag ctcgcgcgca gcctgccgct ggaatccatc gtgctggaaa ccgatgcgcc
     6961 ggacatcccg ccggcgtggg cgcgcggcga gcgcaacctg ccgcagaacc tggcacggta
     7021 cgcgcggatt ctcgctgagc tgcgtcgaat cgacgtggag gaggtgatcg agaagaccgg
     7081 gctcaacctg atggagacgc tcggtggctg gcagccgcac tgagactcag gctgccgcgg
     7141 cgccagtagt gccgacggcg caggagcgcg cgatcaggtc tgcgatgtca cgcttgagac
     7201 gcgcgacgtc gcggtcgaac ttctcgtaga tcatcagcga tacaccgaag acataggcgt
     7261 agagcagcat gcagcggctg gaggcctctt ccatcggtac gccgcaggcg aggaagaggt
     7321 cgcgcgcgca gcgcaggcgg acatcgtcaa cctcggccac gatcgcgccc gcctcggcgt
     7381 cacggcgcgc ccagtcgcgc acggcgagct cgatcatcat gccgcggcgg ctgcggctcg
     7441 cgctatacac gtcgatgacg tggtagatct gctcgagctc gcggcccggt tgggcgcggg
     7501 tctgcttgat gatgtcgcga atgcggcctt ccttccagtg cgtgagtacc gccatcagca
     7561 ggtcgcggcg gtcggtgaag tgccagtaaa aactgccctt ggttaccttg agccgtttcg
     7621 ccagcacttc gacgcgcagg cccgcgatgc cttcctcggc gagcacctcg gtggcgccgg
     7681 cgacccaggc ggcccggtcg agttgggtac gcggcttttt cacgatgttt tccatacgca
     7741 gtagtattga cgattcgacg accatacgct accgtacgcg ccatacttga ccgtatggaa
     7801 ttgctgccct gcagcagtgc ggccggccaa gggcggtgac ataatccgga agtcgggccc
     7861 gcatcccggg cctaccatcc cctgcaaaga agaggagcgc gtcagagtga agattctcgt
     7921 acccgtaaag cgcgtggtcg attacaacgt caaggttcgc gtgaaggccg
//
LOCUS       DAOTIN010000144         7930 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_10984_length_7930_cov_8.114032, whole genome shotgun sequence.
ACCESSION   DAOTIN010000144 DAOTIN010000000
VERSION     DAOTIN010000144.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 7930)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 7930)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7930
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_10984_length_7930_cov_8.114032"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..430)
                     /locus_tag="P5537_14980"
     CDS             complement(<1..430)
                     /locus_tag="P5537_14980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase"
                     /protein_id="HRV79390.1"
                     /translation="MGVTIAIDCMGGDHGPVVTVPAALEFLRSHPQASAILVGREEAI
                     APLLGNASTEFGARIRVRAASEVVAMDDPPAIAMRNKKDSSMRVAVDLVKAGEANAAV
                     SAGNTGALMAISRFVLKTLPGIDRPAIDSRQGLQHEARDRH"
     gene            complement(526..705)
                     /gene="rpmF"
                     /locus_tag="P5537_14985"
     CDS             complement(526..705)
                     /gene="rpmF"
                     /locus_tag="P5537_14985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HRV79391.1"
                     /translation="MAVQQNKKSPSKRGMHRAHDFLTGPALAVEPTTGETHLRHHVSP
                     SGFYRGKKVAKGKGE"
     gene            complement(735..1259)
                     /locus_tag="P5537_14990"
     CDS             complement(735..1259)
                     /locus_tag="P5537_14990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004382902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceD family protein"
                     /protein_id="HRV79392.1"
                     /translation="MSQHGDPSRIIPDPFRFAAEARTLEGVAAVADMLRLTDALASSV
                     GQVSWRIEGSMVDGVEGLEPRLRLVVEGELQLCCQRCLGGMAWPVKVDSSLQPVRSGQ
                     QIPEEELEDDEVDAIELDGELDVLALVEDEILLALPIAPRHQVCDAPQPEGGVSKESP
                     FAALASLRGSHSAN"
     gene            1401..1976
                     /locus_tag="P5537_14995"
     CDS             1401..1976
                     /locus_tag="P5537_14995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030428 - cell septum [Evidence IEA];
                     GO_process: GO:0000917 - division septum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Maf family nucleotide pyrophosphatase"
                     /protein_id="HRV79393.1"
                     /translation="MKIVLASTSAYRRMLLERLQLPFDTDRPETDESPLPGEPPAVTA
                     ERLALEKARAVAARWPDALIIGSDQVAHLGDEVFGKPGTEARAIAQLQRMRGQTVVFH
                     TALALLDTRSGHAQIDGVPTHVRFRDLSDDEIRRYVERERPLDCAGSAKSEGLGITLL
                     EAMSGDDPTALIGLPLIALSRMLRAAGVQLP"
     gene            1973..2701
                     /locus_tag="P5537_15000"
     CDS             1973..2701
                     /locus_tag="P5537_15000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011765351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HRV79394.1"
                     /translation="MTEPRPRRGSLYLVPVALGEHTPWAHFLPAQAQAIAAGLRHFVV
                     ETARAARAHLKQLDYPHPLRETDIRELPAEAADAVLDTLLAPALAGADLGLLSDAGCP
                     AVADPGARLVARAHALDIRVVPLVGPSSILLGLMGSGLNGQSFAFHGYLPVAEGERDA
                     ALRTLEDESRRLGRTQIFIETPYRNERMFEALLRTLKPETRLCVACELNTAGELLLTR
                     PVREWKKAARPALARRPALFLLLA"
     gene            complement(2717..3373)
                     /locus_tag="P5537_15005"
     CDS             complement(2717..3373)
                     /locus_tag="P5537_15005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HRV79395.1"
                     /translation="MAERFDLIVFDWDGTLMDSAAAIVRAMQAAARDLDLPPPPEERA
                     RYVIGLGLGDALRHAIPELEEAAYPRMVERYRHHYLSSDHELSLFEGVDALIDALAGR
                     GHLLAVATGKSRVGLNRALGHTGLGRYFHATRCADECFSKPHPAMLEELMDELGATPE
                     RTLMIGDTTHDLQMAKNARTGGLAVGFGAHPMEVLAAESPLACVRTPGELAGWLLANA
                     "
     gene            complement(3366..4325)
                     /locus_tag="P5537_15010"
     CDS             complement(3366..4325)
                     /locus_tag="P5537_15010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HRV79396.1"
                     /translation="MTTIEGKAIVVRHERIDEAAAGQRIDNYLLRIAKGVPKSHVYRI
                     LRSGEVRVNGRRVQQTYRLQEGDEVRIPPIRVAEPTRAAPAPAGKPLPVVYEDDALLV
                     IDKPSGKAVHGGSGVSYGVIEQLRVQRPELRMLELAHRLDRETSGLLIVAKKRSALTA
                     LHDMMRDGAVQKRYLTLVPGRWSNPLQHVKAPLFKYLTAEGERRVRVADDGKAAHSIV
                     RLVRRWRDYSLLEVELKTGRTHQIRVHLAHLGFALCGDDKYGDFALNKRLEGEGLRRM
                     FLHAAQLRFAHPLTGAPLAFESPLPADLQSFLDRLDAAEKKNG"
     gene            4777..>6708
                     /locus_tag="P5537_15015"
     CDS             4777..>6708
                     /locus_tag="P5537_15015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - ribonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HRV79397.1"
                     /translation="MKRMLFNATQAEELRVAIVDGQKLIDLDIESAAKEERKSNIYKA
                     VITRIEPSLEAAFVDYGADRHGFLPFKEISRSYFQPGADAKASIKEALKEGQELIVQV
                     EKDERGNKGAALTTYISLAGRYLVLMPNNPRGGGVSRRVEGDERAELRENMDQLDVPQ
                     GMSLIARTAAIGRSAEELQWDLNYLLQLWTAIEGAAQSQSGAFLIYQEGSLVIRAIRD
                     YFQPDIGEILIDTDDIYDQATQFMAHVMPGNVARVKRYSDDVPLFSRFQIEHQIESAY
                     SRQVNLPSGGAVVIDHTEALVSIDVNSGRATKGSDIEETAFRTNCEAADEIARQLRLR
                     DLGGLIVIDFIDMESAKNQREVENRLRDALRHDRARVQTGKISRFGLLELSRQRLRPA
                     LAETSYITCPRCNGTGHIRSTESSALHIVRILEEEAMKDNTGAVHLQVPVDVATFLLN
                     EKRVDIARIEMRHKVQLIIVPNRHLETPAHEIIRLRHDQLNAEDIALASYQMVQKPVE
                     EDARLPSKTSERPTRPEAAVKGIAPSQPAPMAAAEPAPAPAPTPAAPEPKGLIARIMG
                     WFSAGKTAPAPAPAAAVEDTPKREARPRGERSGEGRRNGGSNGGRGRRGERDGEAQAS
                     TRGNRSERGERSDRSERSDR"
     assembly_gap    6709..6808
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <6809..>7930
                     /locus_tag="P5537_15020"
     CDS             <6809..>7930
                     /locus_tag="P5537_15020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ribonuclease E/G"
                     /protein_id="HRV79398.1"
                     /translation="ERSDRSERSDRGERSDRGEGNERPQRIATERAERPERAERTERG
                     EGGRRGRSQRGERAAEGAELRATPVEDDLLKAASAAAMTAAVATPEAGATEVVASTEA
                     AEEEGTPSEKRRRRGRGRGRRASEAQGTSVGAEAGAEAEVSSAEGSPATAGSPLIAAG
                     SATAELADATLERDGSFMEASTPSPASVEETAELPIASSAAHDIEPVVTPAPEALLAP
                     VAIGGPVEATTEIATTMGVAAPAPAETIETASVEPVPAAEEAVVEHAAAAEAPAAELP
                     EPEAAPVIESAAAEEAPAAFEGAAPTMPLVDIEPARAPEPEPSATKIGGTTSEAAAEL
                     RTAEAAQPFDIDALEAAEQAALSAFESTVVRAMEAGRAA"
BASE COUNT         1306 a         2857 c         2610 g         1057 t
ORIGIN      
        1 gatggcgatc tcgcgcttcg tgctgaagac cctgccggga atcgatcgcg gggcggtcga
       61 ttcccggcag ggtcttcagc acgaagcgcg agatcgccat cagcgcgccg gtgttgcccg
      121 ccgagacggc cgcgttcgcc tcgcctgcct tgacgaggtc caccgcgacc cgcatcgacg
      181 agtccttctt gttgcgcatg gcgatcgcgg gcggatcgtc catggccacg acctcggagg
      241 ccgcgcgcac gcggatgcgt gcgccaaatt cggtgctcgc gttgccgagc aggggcgcga
      301 tcgcctcctc ccgcccgacg aggatcgcgc tggcctgggg atggctgcgc aggaattcca
      361 gcgcggcagg cacggtcacg accgggccgt gatcgccacc catgcagtcg atcgcaatgg
      421 tgacacccat cgggttctcg cgtgatttca ggttctagga gccggaaaaa aggcggcgcc
      481 ggcgcagtgc gcccgacgcc gcccttcgga attcaggcag caggattact cgcccttgcc
      541 cttggcgacc ttcttgccac ggtagaagcc gctcgggctc acgtgatggc gcaggtgggt
      601 ctcacccgtg gtgggctcga cggccagcgc cggaccggtg aggaagtcgt gggcacgatg
      661 catgccacgc ttggaggggg acttcttgtt ctgctgaacg gccatgagta agactcctaa
      721 gacaaatatc gcgcctagtt cgcgctgtga ctgcctcgca gcgacgccag cgcagcgaaa
      781 ggcgattcct tcgacacgcc accctcgggc tggggcgcat cacaaacctg gtgtcgcggg
      841 gcgatcggca aggcgagcag gatctcgtcc tcgaccaggg caagcacgtc gagctcgccg
      901 tcgagctcga tcgcatcgac ctcgtcgtcc tcgagctctt cctcggggat ctgctgcccg
      961 gaacgcaccg gctgcagcga ggaatcgacc ttcaccggcc acgccatccc gccgagacag
     1021 cgctggcagc aaagctgcaa ctctccctcg accacaaggc gcaggcgcgg ctcgagcccc
     1081 tcgacgccat cgaccatcga cccctcgatc cgccacgaca cctgccccac ggaagacgca
     1141 agcgcatccg tcaggcgcag catgtccgcg actgcggcaa cgccttccag cgtgcgcgcc
     1201 tccgcagcga aacgaaacgg gtcggggatg atcctggacg gatcgccatg ttgcgacata
     1261 agccgcgcat gataatattt ttcggatccg cctgtaaagg cttcattcaa ttcgggaagc
     1321 gtttccgcac gcccttccct ccagcacagt cgcgtgagct ccacggccag tcggcgccgg
     1381 agcaagcatg caccgaagcc atgaagatcg tcctcgcctc cacctccgcc taccgcagga
     1441 tgctgctcga gcgcctgcaa ctgcccttcg acaccgaccg accggagacc gacgagtcgc
     1501 cgctgcccgg cgagccccct gccgtcaccg ccgaacgcct ggcgctcgag aaggcgcgcg
     1561 cggtcgccgc gcgctggccc gacgcgctga tcatcggctc cgaccaggtc gcgcacctcg
     1621 gcgacgaggt cttcggcaag cccggcaccg aggcgcgcgc gatcgcgcag ctgcagcgca
     1681 tgcgcggcca gaccgtggtc ttccacaccg cgctcgccct gctcgacacg cgcagcggac
     1741 acgcgcagat cgacggcgtg ccgacgcacg tgcgcttccg cgacctcagc gacgacgaga
     1801 tccgccgcta cgtcgagcgc gaacgcccgc tcgactgcgc aggcagcgcc aagtccgaag
     1861 gactcggcat caccctgctc gaggcgatga gcggcgacga ccccaccgcg ctgatcggcc
     1921 tgccgctgat cgcgctctcg cgcatgctcc gcgccgccgg agtgcagctg ccatgaccga
     1981 gcccaggcca cggcgcggca gcctctatct cgtcccggtg gcgctcggcg agcacacgcc
     2041 ctgggcgcac ttcctgcccg cgcaggcgca ggcgatcgcc gcaggcttgc gccacttcgt
     2101 ggtggagacg gcgcgcgctg cgcgcgccca cctcaagcag ctcgactatc cgcacccgct
     2161 gcgcgagacc gacatccgcg agctccctgc cgaagccgcg gacgccgtgc tcgacaccct
     2221 gctcgccccc gcgctcgccg gcgccgacct cggcctgctc tcggacgccg gctgcccggc
     2281 ggtggccgac cctggcgccc gcctcgtggc gcgcgcgcac gcgctggata tccgggtcgt
     2341 gccgctggtc ggcccctcct ccatcctgct cgggctgatg ggctcggggc tcaacggcca
     2401 gagcttcgcc ttccacggct acctgccggt ggccgagggc gagcgcgacg ccgcgctgcg
     2461 cacgctcgag gacgagtcgc gcaggctcgg gcgcacgcag atcttcatcg agacgcccta
     2521 tcgcaacgag cgcatgttcg aggcgctgct ccgcacgctg aagcccgaaa cccggctgtg
     2581 cgtggcctgc gagctcaaca ccgcgggcga gctgctcctc acccgcccgg tgcgcgagtg
     2641 gaagaaggcc gcacgccccg ccctcgcccg ccgcccggcg ctcttcctgc tgctggcctg
     2701 aacggcgccg cgtagctcag gcgttcgcca gcagccagcc ggccagctcg cccggcgtgc
     2761 gcacgcaggc gagcggagat tccgcagcga gcacctccat cgggtgcgcg ccgaagccca
     2821 ccgccaggcc gccggtgcgg gcgttcttgg ccatctgcag atcgtgggtg gtgtcgccga
     2881 tcatcagggt gcgctcgggc gtcgcaccga gctcgtccat cagctcctcc agcatcgccg
     2941 gatgcggctt ggagaagcac tcgtcggcgc agcgcgtggc gtggaagtag cgccccagcc
     3001 cggtgtggcc gagcgcgcgg ttcaagccca cgcggctctt gccggtggcg accgcgagca
     3061 ggtggccgcg cccggcgagc gcgtcgatca gcgcatccac gccctcgaag aggctcagct
     3121 cgtggtccga agacagatag tggtggcggt agcgctccac catgcgcgga taggcggcct
     3181 cctcgagctc ggggatcgcg tggcgcagcg catcgcccag gccgagaccg atcacgtagc
     3241 gggcgcgctc ctcgggcggc gggggcaggt cgaggtcgcg cgccgcggcc tgcatcgcgc
     3301 gcacgatggc ggcggccgag tccatcaggg tgccgtccca gtcgaagacg atgaggtcga
     3361 agcgttcagc catttttttt ctccgcggcg tcgagccggt cgaggaagga ttgcaggtcc
     3421 gcgggcagcg gcgactcgaa ggcgagcggc gcaccggtga gcgggtgggc gaagcgcagc
     3481 tgcgccgcgt gcaggaacat gcgccgcaag ccctcaccct cgaggcgctt gttgagcgcg
     3541 aagtcgccgt acttgtcgtc gccgcacagc gcgaagccga ggtgggccag atgcacgcgg
     3601 atctgatgcg tgcgcccggt cttgagttcc acctcgagca ggctgtagtc gcgccagcgc
     3661 cgcaccaggc gcacgatgct gtgcgccgcc ttgccgtcgt cggcgacgcg cacgcggcgc
     3721 tcgccctcgg cggtcaggta cttgaacagc ggcgccttga cgtgctgcag cggattcgac
     3781 caacgccccg gcaccagggt gaggtagcgc ttctgcaccg cgccgtcgcg catcatgtcg
     3841 tgcagcgcgg tgagcgccga gcgcttcttc gccacgatca gcaggccgga ggtctcgcgg
     3901 tcgaggcgat gtgcgagctc gagcatgcgc agttccgggc gctgcacgcg cagctgctcg
     3961 atcacaccgt agctcacgcc gctgccgcca tggaccgcct tgccggaagg cttgtcgatg
     4021 accagcagcg cgtcgtcttc atacaccacc ggcaaaggct tgcccgccgg cgcgggtgcg
     4081 gcgcgggtcg gctcggcgac gcggatcggc ggaatgcgta cctcgtcgcc ctcctgcagg
     4141 cgataggtct gctgcacgcg tcgcccgttc acccgcacct cgccgctgcg caggatgcga
     4201 tagacgtggc tcttgggcac gcccttggcg atgcgcagga ggtagttgtc gatacgctgg
     4261 ccggctgcgg cctcgtcgat gcgttcgtgg cgaaccacga tcgctttgcc ttcaatcgtc
     4321 gtcatgaaat atactttcgc gcggtttgac cggtcgctgc cacccaagtg cggcgcgtca
     4381 ccagtccgtc aggtcgaaac acctgctccg gacgacgcgc gcagactgct ggcaaagagc
     4441 cctgaagagc gctcccggtt gaaacccttg cccgccatcc aaggccgaaa aggcgccgat
     4501 ggtaacgcaa gcgatcccct tcgacacacc catccagccc ccgggttgga ttttgacgcg
     4561 cgagtcaccg acgcaggatc aaatgttccg gccacgcagc cgcaccggca ccgcgggcgg
     4621 gaacaagaga aattcgacca gccgacccat cacagccctg ttaacccacc ggatgaaagc
     4681 agcagcagcc ctacccaatc gctcctgatc ccggaaagcg cgatggtgcg cgccgttcgt
     4741 cctgcccgtg tgtcttctcg cgggagaacg atccaaatga agcgcatgct tttcaatgcg
     4801 acgcaggccg aagaactgcg cgtcgcgatc gtggacggtc agaaactgat cgacctcgat
     4861 atcgaatcgg ccgccaagga agaacgcaag agcaacatct acaaggccgt catcacgcgc
     4921 atcgagccca gcctcgaggc agctttcgtg gactatggcg ccgaccgcca cggcttcctg
     4981 ccgttcaagg aaatctcgcg ttcctacttc cagcccggcg cggacgccaa ggcctcgatc
     5041 aaggaggccc tgaaggaagg ccaggagctc atcgtccagg tcgagaagga cgagcgcggc
     5101 aacaagggcg ctgcgctcac cacctacatc tcgctcgccg gccgctacct ggtgctcatg
     5161 cccaacaacc cgcgcggcgg cggcgtctcg cgccgcgtcg agggcgacga gcgcgccgaa
     5221 ctgcgcgaga acatggatca gctcgacgtg ccgcagggca tgagcctgat cgcccgcacc
     5281 gccgccatcg gccgcagcgc ggaagagctg cagtgggacc tcaactacct gctgcagctg
     5341 tggactgcca tcgagggcgc ggcgcagagc cagtccggcg ccttcctgat ctaccaggaa
     5401 ggcagcctgg tgatccgcgc gatccgcgac tacttccagc ccgacatcgg cgagatcctg
     5461 atcgacaccg acgacatcta cgaccaggcc acgcagttca tggcccacgt gatgccgggc
     5521 aacgtcgcgc gcgtgaagcg ctacagcgac gacgtgccgc tgttctcgcg cttccagatc
     5581 gagcaccaga tcgaatcggc ctactcgcgc caggtgaacc tgccgtcggg cggcgccgtg
     5641 gtcatcgacc acaccgaggc gctggtctcg atcgacgtca actcgggtcg cgccaccaag
     5701 ggctcggaca tcgaggagac cgccttccgc accaactgcg aggcggccga cgagatcgcc
     5761 cgccagttgc gcctgcgcga cctcggcggc ctgatcgtca tcgacttcat cgacatggag
     5821 tcggccaaga accagcgcga ggtcgagaac cgcctgcgcg acgccctgcg ccacgaccgc
     5881 gcccgcgtgc agaccggcaa gatcagccgc ttcggcctcc tcgagctgtc gcgccagcgc
     5941 ctgcgcccgg cgctcgccga gaccagctac atcacctgcc cgcgctgcaa cggcaccggc
     6001 cacatccgca gcaccgagtc gtcggcgctg cacatcgtgc ggatcctcga agaagaggcg
     6061 atgaaggaca acaccggcgc cgtgcacctg caggttccgg tcgacgtcgc caccttcctg
     6121 ctcaacgaga agcgggtcga catcgcccgc atcgagatgc gccacaaggt gcagctcatc
     6181 atcgtgccca atcgccacct cgagacgccg gcgcacgaga tcatccgcct gcgccacgac
     6241 cagctcaacg ccgaggacat cgcgctggcg agctaccaga tggtgcagaa gcccgtcgag
     6301 gaagacgccc gcctgccctc caagaccagc gagcgcccga cccgacccga agccgcggtc
     6361 aagggcatcg ccccgtcgca gccggccccg atggccgccg ccgagccggc ccccgcgccc
     6421 gccccgaccc ccgcagcgcc cgagcccaag ggcctgatcg cgcgcatcat gggctggttc
     6481 tcggccggca agaccgcgcc agcccctgca cccgcagcgg cggtcgaaga cacccccaag
     6541 cgcgaggcgc gtccgcgcgg cgagcgcagc ggcgaagggc gacgcaacgg cggcagcaac
     6601 ggcgggcgcg gtcgtcgcgg tgagcgcgac ggcgaggcgc aggcctcgac ccgcggcaac
     6661 cgcagcgagc gtggcgagcg cagcgaccgt agcgagcgca gcgaccgtnn nnnnnnnnnn
     6721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6781 nnnnnnnnnn nnnnnnnnnn nnnnnnnngc gagcgcagcg accgtagcga gcgcagcgac
     6841 cgtggcgagc gcagcgaccg tggcgagggc aacgagcgtc cccagcgcat cgccaccgag
     6901 cgcgcggagc gccccgagcg ggcggaacgc acagagcgcg gcgaaggcgg ccgccgtggc
     6961 cgcagccagc gcggcgagcg cgccgcggaa ggcgccgagc tgcgcgcgac gccggtagag
     7021 gacgatctgc tgaaggccgc cagcgctgcg gccatgaccg cggccgtcgc taccccggag
     7081 gcaggcgcga ccgaggtcgt cgccagcacc gaagccgctg aagaggaagg caccccgtcc
     7141 gagaagcgcc gccgtcgcgg ccgtggtcgc ggacgccgcg cgagcgaggc gcagggcacc
     7201 agcgtgggcg ccgaagcggg cgccgaagcg gaggtctcct ccgcagaagg ctcgcccgcg
     7261 acggcaggat cgccgctgat cgctgccggc agcgccaccg cggagcttgc cgacgcaacg
     7321 ctcgaacgcg acggctcgtt catggaagcg tcgacgcctt cccctgcaag cgtggaggaa
     7381 acggccgagc tgccgatcgc cagcagcgcg gcgcacgaca tcgaaccggt cgtcacgcct
     7441 gcgccggagg ccctcctggc tccagtggcc atcggcgggc ccgtggaggc caccacggag
     7501 atcgcgacca cgatgggggt cgccgcgcca gccccggctg agacgatcga gacggcatcg
     7561 gtcgaacccg ttcctgctgc cgaggaagca gtcgtcgagc atgcggccgc agcggaggcg
     7621 ccggctgccg aactgcccga gccggaagcg gctccggtga tcgagtcggc tgctgccgag
     7681 gaagcgcccg cggctttcga gggggctgcc ccgaccatgc cgctcgtcga catcgagccc
     7741 gcacgcgcgc ccgagccgga accttccgca acgaagatcg gcggcacgac ctccgaggca
     7801 gccgcggagc ttcgaacggc ggaggctgcg cagcctttcg acatcgacgc cctcgaggca
     7861 gccgaacagg ccgccctcag cgccttcgaa tcgaccgtgg tccgggcaat ggaagcgggc
     7921 cgcgccgctc
//
LOCUS       DAOTIN010000145         7798 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_11222_length_7798_cov_8.552628, whole genome shotgun sequence.
ACCESSION   DAOTIN010000145 DAOTIN010000000
VERSION     DAOTIN010000145.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 7798)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 7798)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7798
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_11222_length_7798_cov_8.552628"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(141..509)
                     /locus_tag="P5537_15025"
     CDS             complement(141..509)
                     /locus_tag="P5537_15025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004315806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV79399.1"
                     /translation="MNKLAFIIDDSAVNIAVARLLLRRLGWTVEDFASAIPMLARLAE
                     VQPAFMLLDISMPDLGGEEACRMIRANPAWSGVRIIAYTAHAMEVERQRYLAGGFDAV
                     ITKPVTIGALKDVVGDAPNE"
     gene            complement(506..3073)
                     /locus_tag="P5537_15030"
     CDS             complement(506..3073)
                     /locus_tag="P5537_15030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HRV79400.1"
                     /translation="METPRAIRGMSLRAKLVAIFIAIKVVPLVLLAVFAWSAARDLGQ
                     LVTLRAVSMSDVMRDTQMRTGQTAIDDAIDALDDRSREAIETLTTATARSIAQFLRER
                     DSDVRLAASLPTDEASYRSFMDARVRNIEEHGPYTLDTEGERWVERDPQPRELALVRA
                     PLPDNSDSFHYRAPDTHMRGTPRPLFLEMSFIDLDGRERIKVLSDTGRLLLDAGLRDI
                     TRRENTFVRAETYWPALQALRPGEIHVSRVIGAQVRTHWIGDYTPARAKALGKPFAPE
                     DSGYAGLENPVGKRFQGLIRWATPVLREDRIVGYVTLALDHAHLMAFTDTLRPTSERF
                     APIADPASGNYAFIWDDEGHNISHARDYFIHGYDPATGERTVPWLDRELYEAWRGSGQ
                     SWPAFSAALTPYQDQRLGREPHPESTASGLVGLDCRFLDFSPQCQGWHDMTEHGGSGS
                     FNILFTGVRKLTTVATIPYYTGPYGRSPRGFGYVTIGANVEDFHRAATESGERIGKMI
                     GDADALTQQERDTLVGDIADSLRGTTTSLAASTLAMVLAVILIAIWMANLLSRRITQV
                     VDGIHRFEQGDLDHRLHATGGDELAELARAFNRMADTVQRSIRSLEDARHTAEQANRM
                     KSEFLANMSHELRTPLNGVIGFAELLSMELEDPEQRECATTIHDSARHLLAVVNDVLD
                     LAKVEANRLTLAEQSIDLVPLITSVAALHKVNAEAKGVDLRVDLPAHPCIVDADPVRL
                     RQIIENLLSNAVKFTREGHILVSLAAGADDVSIRIADTGSGIAREEQERIFAPFYQAE
                     SFLNRGHGGTGLGLTLSRRLAHLMGGTISLDSLSGKGSTFTLHLPRHSAATGGGPQP"
     gene            complement(3101..3715)
                     /locus_tag="P5537_15035"
     CDS             complement(3101..3715)
                     /locus_tag="P5537_15035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004315810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV79401.1"
                     /translation="MAGKPDSKSEFISTAQAARQLGLSLGAVQQMVESGTLAGWKTAG
                     GHRRIRQDSVDALLARARSPSAPTRSGGDRLRVMVVEDDRLLQNIYRETFLTWSLPID
                     VHVMEHGLDALVEVGREPPDLLIADLRIPGIDGFEMIRRLRDNPLSSDIAIVVVSALG
                     PKEIAASGGLPEDITVYRKPIPFHELHGYVQALISIRRRARHAG"
     gene            3926..4312
                     /locus_tag="P5537_15040"
     CDS             3926..4312
                     /locus_tag="P5537_15040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2237 domain-containing protein"
                     /protein_id="HRV79402.1"
                     /translation="MNTSKNVLGGALLACSYSPLTGFYRTGCCETGPDDLGRHVVCVK
                     VDAAFLDFSRRAGNDLSTPRPEYRFAGLKPGDRWCLCALRWKEALDAGVAPPVILEAT
                     HEAALRVIDLDTLKAHAYGTAHGPSA"
     gene            4312..5742
                     /locus_tag="P5537_15045"
     CDS             4312..5742
                     /locus_tag="P5537_15045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004315812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HRV79403.1"
                     /translation="MDDVRAPLRERLAGLLALLEAGLVERRQVLRASLLAALAGEHTL
                     LVGPPGTAKSALARRIHLAFRDARYFERLLTRFTVPEELFGPLSIRALEEDRYERHVA
                     GFLPDAAVAFIDEVFKANSAILNALLTLLNEREFDNGAGRLRCPLISVVGATNVVPED
                     EVAEAFFDRFLLRLTVAPVSAEGFRRLLGEDRAALPEALAPPSALQLDEADLGALAQA
                     AAACALPAAVLDRLAELRAWLAGRGVYVSDRRWVKLAHLLRVAAASEGRAAASEWDLG
                     LVPYCVAADEPARLAVAEWLAARLGVREAWSPPRITRVVEAFEAQLATEREARDLDYD
                     EAGRLRFTASDPAAQAGELAGAIGDAKGGSAALRMSYARMRRYGSLHIGARTAQLDGV
                     LARLAAYRGELGAQRAALEAWAEQALWADPAFIAAARAGLEAVDGALAGLEARARGAR
                     AGFEALPRLEQAGVAPAAVEHDALPE"
     gene            5831..7603
                     /locus_tag="P5537_15050"
     CDS             5831..7603
                     /locus_tag="P5537_15050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HRV79404.1"
                     /translation="MVESSSVASSSVAASSTASRSANDEPTASAAAERTSAPRLPGAA
                     AAAEAPPVPRLFEALEAPLAPLDRLPRALWLGGMTHSGGELAGRLGSLEAWREALLAG
                     GLPPSSAAWPEAELRQAVLEVFGRLGLPGYCADQPELADTVLQGLLFHLDLVVDYRDR
                     GDTEAAAQARAVDSFAADWAERCGDIDELVGAFGDLGDLLKNTRWDALRGLLRSTEWR
                     EVLRIRALIERLPELARILRALGRARPTDELLESSQALQAVVEQAEVQRSVARRVRVP
                     DLPGETRGVQRSGRIARMLPAEAMLLGHPRLRLVWHARRAERTLLAYEDDDHLQEDCL
                     RPAPVLRPIQRPAPERRLERGPMLVCVDTSGSMQGGAEAVAKAVVLEAVRCAHAQRRA
                     CRVYAFGGPDEVVEMELGVDAEGVGRLARFLGQGFGGGTDICGPLERAIARLDEAGWE
                     LADLLIASDGEFGATPALAARVGAARRERGLRVQGILIGDRETIGLLELADDIHWVRD
                     WRRYGSDAGKAGVGDADSRRGVGTSANAPNAAADGGSPVHSSHLTADYFPGALRTPEN
                     RAATLTPEAAAAAIRAGRHRGESP"
BASE COUNT         1008 a         2586 c         3024 g         1180 t
ORIGIN      
        1 ggtgtcggcg agccaggggg cgaaggtctc cagcaccgca cgcacggcgg cgcggctctc
       61 ggacatgtcg ctgctcaggg cggcgaggtc gaaatgggag ggagattcgg agtggtcggg
      121 tgccatggcg gtctcggtgc tcattcgttc ggtgcgtctc cgaccacgtc cttcagcgcg
      181 ccgatggtga ccggcttggt gatgaccgcg tcgaagccgc cggcgaggta gcgctggcgc
      241 tcgacctcca tcgcgtgcgc ggtgtaggcg atgatgcgca cgccgctcca ggcggggttg
      301 gcgcggatca tccggcaggc ttcctcgccg ccgaggtcgg gcatggagat gtcgagcagc
      361 atgaaggcgg gctgcacttc ggcgaggcgc gcgagcatcg ggatcgcgct cgcgaagtcc
      421 tccacggtcc agcccagccg gcgcaggagc aggcgggcga cggcgatgtt gaccgcgctg
      481 tcgtcgatga tgaaggcgag cttgttcatg gttgcgggcc gcccccagtg gcggcagagt
      541 ggcgcggcag gtgcagggtg aaggtcgagc ccttgccgga gagcgagtcg aggctgatcg
      601 tgccgcccat caggtgggcg agccggcgcg acagcgtgag gcccaggccg gtgccgccgt
      661 ggccgcggtt gaggaaggat tcggcctggt agaagggcgc gaagatgcgc tcctgctctt
      721 cccgtgcgat gccgctgccg gtgtcggcga tgcggatcga cacgtcgtcg gcgccggcgg
      781 cgaggctgac caggatgtgg ccttcgcggg tgaacttcac cgcgttggag agcaggttct
      841 cgatgatctg gcgcaggcgc accgggtcgg cgtccacgat gcatgggtgg gcgggcaggt
      901 ccacccgcag gtcgacgccc ttcgcctctg cattgacctt gtgcagcgcg gccaccgagg
      961 tgatcagcgg gacgaggtcg atgctctgtt ccgccagcgt cagccggttg gcctcgacct
     1021 tggcgaggtc gaggacgtcg ttgaccaccg cgagcaggtg gcgcgcgctg tcgtggatgg
     1081 tggtcgcgca ctcgcgctgc tcggggtcct cgagctccat gctgagcagc tcggcgaagc
     1141 cgatcacgcc gttgagcggg gtgcgcagct cgtgcgacat gttggcgagg aactcgctct
     1201 tcatgcggtt tgcctgctcg gcggtgtggc gggcatcctc caggctgcgg atcgagcgct
     1261 ggacggtgtc ggccatgcgg ttgaaggcgc gggccaactc ggcgagctcg tcgccgccgg
     1321 tcgcatggag gcggtggtcg aggtcgccct gctcgaagcg gtggatgcca tcgaccacct
     1381 gggtgatgcg gcgcgagagc agattggcca tccagatcgc gatcaggatc accgcgagca
     1441 ccattgccag ggtggaggcg gccaggctgg tggtggtccc gcgcaggctg tcggcgatgt
     1501 cgccgaccag ggtgtcgcgt tcctgctggg tgagggcgtc ggcgtcgccg atcatcttgc
     1561 cgatgcgctc gccggattcg gtggcggcgc gatggaagtc ttccacgttg gcgccgatgg
     1621 tcacgtagcc gaagccgcgc gggctgcggc cgtaggggcc ggtgtagtag ggaatggtgg
     1681 cgacggtggt gagcttgcgc acgccggtga agaggatgtt gaacgagccc gagccgccat
     1741 gctcggtcat gtcgtgccag ccctggcact gcggcgagaa gtcgaggaag cggcagtcga
     1801 gcccgacgag gccggaggcg gtggactcgg ggtggggctc gcggccgagg cgctggtcct
     1861 ggtagggcgt cagggcggcg gagaaggccg gccaggactg tccgctgccg cgccaggcct
     1921 cgtagagctc gcggtcgagc cagggtacgg tgcgttcgcc ggtcgcaggg tcgtagccgt
     1981 ggatgaagta gtcgcgcgcg tgcgagatgt tgtggccttc gtcgtcccag atgaaggcgt
     2041 agttgccgga ggcggggtcg gcgatcggcg cgaagcgctc ggaggtcggg cgcagggtgt
     2101 cggtgaaggc catcagatgc gcgtggtcga gcgccagcgt gacgtagccg acgatcctgt
     2161 cctcgcgcag caccggggtc gcccaccgga tcagcccctg gaagcgcttg ccgaccgggt
     2221 tctccaggcc ggcatagccg gagtcctccg gggcgaaggg cttgccgagg gccttcgcgc
     2281 gcgcgggggt gtagtcgccg atccagtgcg tgcgcacctg ggcgccgatc acgcgcgaga
     2341 cgtggatctc gccggggcgc agggcctgca gtgcgggcca gtaggtctcc gcgcgcacga
     2401 aggtgttctc gcgccgggtg atgtcgcgca gacctgcgtc gagaagcagg cggccggtgt
     2461 cgctgagcac cttgatgcgc tcgcggccgt cgaggtcgat gaagctcatc tcgaggaaga
     2521 gcgggcgcgg ggtgccgcgc atgtgggtgt cgggtgcgcg gtaatggaag ctgtcggagt
     2581 tgtccggcag cggggcgcgc accagggcta gctcgcgggg ctgcggatcg cgctcgaccc
     2641 agcgctcgcc ctcggtgtcg agcgtatagg gtccgtgctc ctcgatgttg cgcacgcggg
     2701 cgtccatgaa gctgcgatag ctggcctcgt ccgtgggcag gctggcagcc agccggacgt
     2761 cgctgtcgcg ttcgcggagg aactgcgcga tgctgcgcgc ggtggcggtg gtgagcgtct
     2821 cgatggcctc gcgcgagcgg tcgtcgaggg catcgatggc gtcgtcgatc gcggtctggc
     2881 cggtgcgcat ctgcgtgtcg cgcatcacgt cggacatgct gaccgcgcgc agcgtgacga
     2941 gctggccgag gtcgcgcgcc gcgctccagg cgaacaccgc gagcagcacc agcggtacga
     3001 ccttgatcgc gatgaagatc gcgaccagct ttgcgcgcag gctcatgccg cggatcgcgc
     3061 gaggggtttc catcgtgcgg gggcgcgtca gccggagcgc tcagccggcg tggcgagcgc
     3121 ggcggcgtat cgagatcagc gcctggacgt agccgtgaag ctcgtggaag gggatgggct
     3181 tgcgatacac cgtgatgtcc tcgggcaagc cgcctgaagc ggcgatctcc ttggggccga
     3241 gtgcggacac gacgacgatg gcgatgtcgc tcgagagcgg gttgtcacgc aggcggcgga
     3301 tcatctcgaa accgtcgatc ccggggatgc gcaggtcggc gatgagcagg tcgggcggct
     3361 cgcggcccac ctcgacgagc gcgtcgaggc catgctccat cacgtgaacg tcgatcggca
     3421 ggctccacgt gagaaaggtc tcgcgataga tgttctgcag caggcgatcg tcctcgacca
     3481 ccatcacgcg caggcgatca ccgccgctgc gagtcggcgc agagggcgag cgtgctcggg
     3541 cgagcagggc gtcgaccgag tcctggcgga tgcggcggtg gccgccggcg gtcttccagc
     3601 cggccagcgt tccgctttcg accatttgct gcacggcacc gagcgacagg ccgagctggc
     3661 gcgctgcctg ggcagtgctg atgaactcgg atttggagtc gggttttccg gccatgtgga
     3721 tctgcgattc gatggaatga ttaaaagtac cagaattatg gcaccggggg ggccgggcgc
     3781 gaagggaatt ttcaggatgg aggcatagac ccgacccggg tgcgcagcgg acgagcgggg
     3841 ccgctacaat gaagtggttg cggttggccg cggacgtcgt ggacgttcgc gcttgccgcc
     3901 ttggaagact tccggatcgc cgaccatgaa cacttcgaag aacgtgctgg gcggagcctt
     3961 gctcgcctgc agctactctc cactgaccgg gttctaccgt accgggtgct gcgagaccgg
     4021 tcccgacgac ctcggtcgcc acgtcgtgtg cgtgaaggtc gacgcggcct tcctcgactt
     4081 ctcgcggcga gccggcaacg acctgtccac gccgcgaccg gagtaccgct tcgccgggct
     4141 caagccgggc gaccgctggt gcctgtgcgc gctgcgctgg aaggaggcgc tcgacgcggg
     4201 cgtggcgccg ccggtgatcc tcgaggccac ccacgaggcg gccctgcgtg tgatcgacct
     4261 cgataccctc aaggcgcacg catacggcac ggcgcacggc ccgagcgcct gatggacgac
     4321 gtgcgcgcgc cgctgcgcga gcgcctggcc gggctgctcg cgctgctcga ggccggcctg
     4381 gtcgagcgcc ggcaggtgct gcgcgcgagc ctgctcgccg cgctcgccgg cgagcacacc
     4441 ctgctggtcg ggccgccggg caccgccaag agcgcgctcg cgcgccgcat ccacctggcc
     4501 tttcgcgacg cgcgctattt cgagcgcctg ctgacccgct tcaccgtgcc ggaggagctc
     4561 ttcgggccgc tgtccatccg cgcgctcgag gaagatcgct acgagcgcca cgtcgccggt
     4621 ttcctgcccg acgccgcggt ggccttcatc gacgaggtct tcaaggccaa cagcgcgatc
     4681 ctgaatgcgc tgctgacgct cctcaacgag cgcgagttcg acaatggcgc cggccgcctg
     4741 cgctgccccc tgatcagcgt ggtgggcgcg accaacgtgg tgcccgagga cgaggtggcg
     4801 gaggccttct tcgaccgctt cctgctgcgc ctgacggtgg cgccggtgag cgcggagggg
     4861 ttccggcgcc tgctcgggga ggatcgtgcg gccttgccgg aggcactcgc gccgccgtcc
     4921 gcgctgcagc tcgacgaggc cgacctcggt gcgctcgcgc aggccgccgc tgcttgtgcc
     4981 ttgccagccg cggtgctcga ccgcctcgcc gagctgcgcg catggctggc ggggcgtggc
     5041 gtgtatgtgt ccgaccgacg ctgggtcaag ctcgcccacc tgctgcgcgt ggccgcggcg
     5101 agcgagggca gggcggcggc gagcgagtgg gacctgggcc tggtgccgta ttgcgtggcc
     5161 gccgacgagc cggcgcggct ggcggtggcg gagtggctgg cggcgcgcct cggggtccgc
     5221 gaggcatggt cgccgccgcg catcacgcgg gtggtggagg ccttcgaggc gcagctcgcc
     5281 accgagcgcg aggccaggga cctcgactac gacgaggcgg ggcggctgcg cttcacggcg
     5341 agcgacccgg cggcgcaggc gggcgagctc gcgggtgcga tcggcgacgc caagggcggg
     5401 tcggcggcgc tgcgcatgag ctatgcgcgc atgcggcgct acggcagcct gcacatcggc
     5461 gcgcgtaccg cccagctcga cggcgtgctc gcgcgcctgg cggcgtaccg cggcgaactc
     5521 ggcgcgcagc gtgcggcgct cgaagcctgg gcggaacagg cgctgtgggc ggacccggcc
     5581 ttcatcgccg ccgcgcgtgc gggcctcgaa gcggtggatg gagcgctggc ggggctcgag
     5641 gcccgcgcgc gcggcgcgcg tgccggcttc gaggcgctgc cgcggctgga gcaggcgggc
     5701 gtggcgcccg cggcggtcga gcacgacgcg ctgccggagt gagggtcggg tgaacgcggc
     5761 ggccggagcg ggtgcgggcg gtgcgtcggc cggcggtttg cccgccggcg cgacgtcggc
     5821 tgcggacccg ttggtcgaga gctcctcggt cgcgagctcc tcggtggcgg cctcctcgac
     5881 tgcaagccgg tcggccaacg acgagccaac cgcttcggcg gccgccgagc gcacgtccgc
     5941 gccgcgcctg cccggtgccg ctgcggccgc cgaggctcca cccgtccccc ggctcttcga
     6001 ggcgctcgaa gccccgctcg cgccgctcga ccgcctgcca cgcgcgctct ggctcggcgg
     6061 catgacccac tccggcggcg aactcgccgg ccgcctcggg tcgctcgaag cctggcgcga
     6121 ggcgctgctc gccggcggcc tgcctccgtc ttctgcggcc tggcccgagg cggagcttcg
     6181 gcaggccgtg ctggaggtgt tcggacgcct cgggctgccc ggctactgcg ccgaccagcc
     6241 cgagctggcc gataccgtgc tgcaaggcct gctcttccac ctcgacctcg tcgtcgacta
     6301 ccgcgaccgc ggcgacaccg aggctgcggc gcaggcgagg gcggtggatt ccttcgccgc
     6361 cgactgggcc gagcgctgcg gcgacatcga tgagctggtc ggcgccttcg gcgatctcgg
     6421 cgacctgctc aagaacaccc gctgggacgc gctgcgcggc ctgctgcgca gcaccgaatg
     6481 gcgcgaggtg ctgcgcatcc gcgcactgat cgagcgcctg cccgagctcg cccgcatcct
     6541 gcgcgcgctc ggccgcgcgc gccccaccga cgagttgctt gaatccagcc aggcactgca
     6601 ggcggtggtc gagcaggccg aggtgcagcg cagcgtggcg cgccgggtgc gggtgccgga
     6661 tctccccggc gagacgcgcg gcgtgcagcg ttcgggccgg atcgcgcgca tgctgccggc
     6721 cgaggcgatg ctgctcggcc atccgcgcct gcgcctggtc tggcacgcgc gccgcgccga
     6781 gcgcacgctg ctggcctacg aggacgacga ccatctccag gaggactgcc tgcgcccggc
     6841 tccggtgctg cgtcccatcc agcgcccggc gccggagcgg cgcctcgagc gcgggccgat
     6901 gctggtgtgc gtggatacct cgggctcgat gcagggtggc gccgaggcag tggccaaggc
     6961 cgtggtgctg gaggcggtgc gctgcgccca cgcccagcgc cgcgcctgcc gggtgtatgc
     7021 cttcggcggg ccggacgagg tcgtggagat ggagctcggc gtcgatgccg agggtgtcgg
     7081 ccggctcgcc cgcttcctcg gccagggctt cgggggcggc accgacattt gcggcccgct
     7141 cgagcgcgcg atcgcccgcc tcgacgaggc cggctgggaa ctcgccgacc tgctgatcgc
     7201 ctccgacggc gagttcggcg ccacccctgc gctcgccgcc cgcgtcgggg ccgcgcgccg
     7261 cgagcgtggc ctgcgcgtgc agggcatcct gatcggcgac cgcgagacca tcggcctgct
     7321 cgaactcgcc gacgacatcc attgggtgcg cgattggcgg cgctatggaa gcgatgcggg
     7381 caaggcgggt gtgggcgacg cggacagccg gcgtggggtt ggcaccagcg cgaatgcccc
     7441 gaacgctgcg gccgacggcg gctcgccggt gcattccagc catctcaccg cagactattt
     7501 ccccggcgcc ctgcgcaccc ccgagaaccg tgctgccacc cttacccccg aggccgccgc
     7561 cgccgccatc cgcgccggcc gtcaccgcgg cgaaagccct tgagccgctt tcgcgcctgc
     7621 cggcgctcct acacaaaccg tcgcggtcca gggggcggcg ccaacatgag ccgccgtggg
     7681 ccggtgcgat gagggccaag ctgtcgccgc ggtccgcggt gaggtgtccc tgaatcaatc
     7741 gccgcgcttc ggggcgatgt aggagcggcg gcagccgcga atgcagcgct gcagtagc
//
LOCUS       DAOTIN010000146         7759 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_11281_length_7759_cov_8.972482, whole genome shotgun sequence.
ACCESSION   DAOTIN010000146 DAOTIN010000000
VERSION     DAOTIN010000146.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 7759)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 7759)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7759
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_11281_length_7759_cov_8.972482"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1311)
                     /locus_tag="P5537_15055"
     CDS             complement(<1..1311)
                     /locus_tag="P5537_15055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004306298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecD"
                     /protein_id="HRV79405.1"
                     /translation="MNRYPLWKNLLIGLVLLWGLLYTLPNFYGEVPAVQVSSAKATLK
                     LDAAATTDRIAGALKAAGIDNTGIFSDANSVRARFKDTETQLRAKDVIEQAFNPDASD
                     PSYVVALNLLSASPSWLTSIQALPMYLGLDLRGGVHFLLEVDMPGALVKRLDSTTGDL
                     RTLMRDKSVRHAGITREGNTVVIRFRDAAQREAGRRAILDSTADLQLVERDDSADDLK
                     LVATLTPQAQQTMRDFAIKQNITTLHNRINELGVAEPVIQQQGAERIVVQLPGVQDVA
                     KAKDILGRTATLEVRMVDDTPGAIEQALAGSVPFGTELYTERGGSPLLVKKQVVLTGD
                     RLTDAQPGFDGQTNEPAVHLTLDAAGARIFRDVTRENVGKRMAILLFEKGKGEVVTAP
                     VIRSEIGGGRVQISGRMSTVEANDVALLLRAGSLAAPMEIIEERT"
     gene            complement(1475..1801)
                     /gene="yajC"
                     /locus_tag="P5537_15060"
     CDS             complement(1475..1801)
                     /gene="yajC"
                     /locus_tag="P5537_15060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002931459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HRV79406.1"
                     /translation="MLISNAYAQAAGAADPTGGLMGLLPLILMFVVLWFLMIRPQMKR
                     AKEHKAMVEALAKGDEVVTGGGIAGRVVEVGDSFVQIEVAPNTVVAAQKQAVATVLPK
                     GTLKAL"
     gene            complement(1893..3005)
                     /gene="tgt"
                     /locus_tag="P5537_15065"
     CDS             complement(1893..3005)
                     /gene="tgt"
                     /locus_tag="P5537_15065"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004306301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - queuine tRNA-ribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HRV79407.1"
                     /translation="MQFELLTTNGGARRGRLTLAHGVVETPVFMPVGTYGTVKAMTPA
                     MLADIGAQICLGNTFHLWLRPGLDIIGAHQGLHRFMAWDKPILTDSGGFQVFSLGALR
                     KITEEGVKFASPIDGAKLFLTPEISMQIQSVLNSDIVMIFDECTPYPATRDEAAKSMR
                     LSQRWAKRSRDEFDRLGNTNALFGIVQGGMYEDLRDESQAALEDIGFHGFAIGGLSVG
                     EPKEDMARILAHTAPRLPQGKPRYLMGVGTPEDIVEGVAAGIDMFDCVMPTRNARNGW
                     LFTRFGDIKIKNAVHKADTRPLDPSCDCYTCRNFSRAYLHHLHRTGEILGSMLNTVHN
                     LRYYQTLTAELRAAIAAGEFVPYVQRFRSERATGTG"
     gene            complement(2995..4071)
                     /gene="queA"
                     /locus_tag="P5537_15070"
     CDS             complement(2995..4071)
                     /gene="queA"
                     /locus_tag="P5537_15070"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004382972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HRV79408.1"
                     /translation="MSLTLADFDYTLPAELIAQAPLPERSASRLLVVEPQENAAPRLT
                     DAVFSALAERIDPCDLLVFNDTRVIHARLHGVKDSGGQVEVLIERPVGPHEALAQVRA
                     SKSPKTGSRLRLADAFEVEVLGRVGEFFHLRFPVGEDLLVLLERHGKLPLPPYIQRAA
                     GEADESRYQTVYAREPGSVAAPTAGLHFDDALLARIAERGAKCAWLTLHVGAGTFQPV
                     RVDDLGEHRMHRERYVIPQETVDAIAATRAAGGRVIAVGTTSMRALEAAAQDGPLEAG
                     SGETEIFILPGFRFQVVDALVTNFHLPKSTLMMLVSAFAGMDSIRRAYAHAVEQRYRF
                     FSYGDAMFITRKNESENDNNDDAV"
     gene            4168..4252
                     /locus_tag="P5537_15075"
     tRNA            4168..4252
                     /locus_tag="P5537_15075"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4202..4204,aa:Leu,seq:caa)
     gene            complement(4486..5382)
                     /gene="nhaR"
                     /locus_tag="P5537_15080"
     CDS             complement(4486..5382)
                     /gene="nhaR"
                     /locus_tag="P5537_15080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004306305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional activator NhaR"
                     /protein_id="HRV79409.1"
                     /translation="MLNYKQLHHFWTVARAGGIVRAAERSGLAPQTLSGQIATLETDL
                     GVNLFKRQGRGLVLTETGRMVLDYAEEIFRLGNELEEALQSRATGRAVPFRVGIADVV
                     PKAIAWLLLAPSMDLPEPMRIVCREGKFDALLGELAIHKLDVVLADSPLPPAMDVRGF
                     SHALGESTIGFYAAPALAARLAGDFPAHLDGAPLLLPGVEASVRGPLLRWIEAAGLRP
                     RIVGEFDDSALMRAFAEAGAGIFPSASLVGEQLCRQGGLVHLGDAKGVTETYYAISVE
                     RRLTHPAVRAISEGAHAKQNFA"
     gene            5533..5865
                     /locus_tag="P5537_15085"
     CDS             5533..5865
                     /locus_tag="P5537_15085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004306307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPF/RaiA family ribosome-associated protein"
                     /protein_id="HRV79410.1"
                     /translation="MRIDLHCDGVETAPGLRDYVAQRMRSSIGRFRDHIQWARVKVAA
                     VNGPEGGTDKRCVVQLRLRNLPDVVFAITQLDVRAAVDEAADRVARVLAQRVRRHQRG
                     PAMAAIPA"
     gene            5959..6624
                     /locus_tag="P5537_15090"
     CDS             5959..6624
                     /locus_tag="P5537_15090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004383054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HRV79411.1"
                     /translation="MENRISTLGRAEVSVLQTNKVIRNTYMLLSLTLAFSALTAGLSM
                     AMGAPRLGILITLVGYFGLLFATTKFRDSSLGIVFVFALTGFMGFTLGPIISSYLALP
                     NGSSIVMQAMAGTAAIFLGLSAYAVTTKKDFSFMGGFLMVGILVAFLAGLGAIFFEIP
                     ALSLTVSAAFVLLMSGLILFETSNIIHGGETNYIMATVSLFVSIFNLFTSLLHLLGFA
                     NND"
     gene            6793..7758
                     /locus_tag="P5537_15095"
     CDS             6793..7758
                     /locus_tag="P5537_15095"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004306310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HRV79412.1"
                     /translation="MKTTFLDFETAISELEEKIDQLRFVQDDPAVDISDEIKRLEAKS
                     QSLTKDLYAKLSPWQIAQVARHPQRPYTLDYASLMFTDFHELHGDRSYADDRAIVGGL
                     ARFNGQACVVIGHQKGRDTKEKIARNFGMPRPEGYRKAMRLMKLAEKFALPVFTFVDT
                     PGAYPGIGAEERGQSEAIGHSIYLMSELKTPIISTIIGEGGSGGALAIAVADRVLMLQ
                     YSTYSVISPEGCASILWKSAEKAADAAETMGITAARLKSLELVDKVIDEPIGGAHRDH
                     RAMAATLKRALADALRELEALSPSELVEQRYQKLMSYGRYKEKAA"
BASE COUNT         1151 a         2566 c         2758 g         1284 t
ORIGIN      
        1 ggtgcgctcc tcgatgatct ccatcggcgc ggccagcgag ccggcgcgca gcagcagcgc
       61 gacgtcgttg gcctcgaccg tgctcatgcg gcccgagatc tgcacgcgcc cgccgccgat
      121 ctcgctgcgg atcaccggcg cggtcacgac ctcgcccttg cccttctcga agagcaggat
      181 ggccatgcgc ttgccgacgt tctcgcgcgt gacgtcgcgg aagatgcgtg caccggcggc
      241 gtccagcgtc aggtgcaccg cgggttcgtt ggtctggccg tcgaagccgg gttgggcgtc
      301 ggtgaggcgg tcgccggtga gcacgacctg cttcttgacc agcagcggcg agccgccgcg
      361 ctcggtgtac agctcggtgc cgaagggcac gctgccggcg agcgcctgtt cgatcgcgcc
      421 cggagtgtcg tccaccatgc gcacttccag cgtggcggtg cggccgagga tgtccttggc
      481 cttggcgacg tcctgcacgc cgggcagctg caccacgatg cgctcggcgc cctgctgctg
      541 gatcaccggc tcggcgacgc caagctcgtt gatgcggttg tgcagggtgg tgatgttctg
      601 cttgatcgcg aagtcgcgca tggtctgctg cgcctgcggc gtcagcgtgg cgaccagctt
      661 gaggtcgtcg gcggaatcgt cacgctcgac gagctgcagg tcggcggtgc tgtccaggat
      721 cgcgcgccgc cccgcctcgc gctgggcggc gtcgcggaag cggatcacca cggtgttgcc
      781 ttcgcgggtg atgccggcgt ggcgcacgct tttgtcgcgc atcagggtgc gcaggtcgcc
      841 cgtggtcgag tcgaggcgct tgaccagcgc gcccggcatg tccacttcga gcaggaagtg
      901 cacgcccccg cgcaggtcga ggccgaggta catcggcagc gcctggatcg aggtcagcca
      961 gctcggcgag gccgacagca ggttaagcgc gaccacgtag gacggatcgg atgcgtcggg
     1021 gttgaaggcc tgctcgatga cgtccttcgc gcgcagctgg gtctcggtgt ctttgaagcg
     1081 ggcgcgcacg ctgttggcgt cggagaagat gccggtgttg tcgatgccgg cggccttcag
     1141 cgcgccggcg atgcggtcgg tggtggccgc ggcgtcgagc ttgagcgtgg ccttggcgct
     1201 ggacacctgc accgccggca cctcgccgta gaagttgggc agggtgtaga gcaggcccca
     1261 gagcagcacg aggccgatca ggaggttctt ccagagggga tagcggttca tcgtcggcgg
     1321 gaatttgggt ggagcggggc ccgacgggac gcgtcgggtc gcgcctgccg ggcgcctggc
     1381 cgcacccgtg gacggggcgg cgatgggatg caggggccgg ccatgggccc gcggcggccg
     1441 ggcggtcgcg ccgcccgccg ccgcgccggg agggtcagag cgccttcagc gtgcccttgg
     1501 gcagcacggt ggcgacggcc tgcttctgcg cggcgaccac ggtgttgggg gcgacttcga
     1561 tctgcacgaa gctgtcgccg acctcgacga cgcgaccggc gatgccaccg ccggtgacga
     1621 cctcgtcacc cttggcgagc gcttcgacca tggccttgtg ctccttcgcg cgcttcatct
     1681 gcgggcggat catcaggaac cacagcacca cgaacatcag gatcagcggc agcaggccca
     1741 tcaggcctcc ggtggggtcg gcggcgccag cggcctgggc gtaggcattg gaaatcagca
     1801 cgttgaaact ccggttggaa gaaaaacgat gaagtatagc agtagccggg atgcggcccg
     1861 ggacgggtga gacggcccgc gcggcgaagg gttcagcccg tgccggtggc gcgctcgctg
     1921 cggaagcgct gcacgtaggg cacgaactcg cccgccgcga tcgccgcgcg cagctcggcg
     1981 gtgagggtct ggtagtagcg caggttgtgc accgtgttga gcatgctgcc gaggatctcg
     2041 cccgtgcggt gcaggtggtg caggtaggcg cggctgaagt tgcggcaggt gtagcagtcg
     2101 caggaagggt ccagcggccg ggtgtcggcc ttgtgcaccg cgttcttgat cttgatgtcg
     2161 ccgaagcggg tgaacagcca gccgttgcgg gcgttgcggg tgggcatcac gcagtcgaac
     2221 atgtcgatgc cggcggcgac gccttccacg atgtcctcgg gcgtgcccac gcccatcagg
     2281 tagcgcggct tgccttgcgg caggcgtggc gcggtgtggg cgaggatgcg cgccatgtcc
     2341 tccttgggct cgccgaccga caggccgccg atggcgaagc cgtggaagcc gatgtcctcg
     2401 agtgcggcct gcgactcgtc gcgcaggtcc tcgtacatgc cgccctggac gatgccgaac
     2461 agggcgttgg tgttgcccag ccgatcgaac tcgtcgcgcg aacgcttggc ccagcgttgc
     2521 gacaggcgca tcgacttcgc ggcttcgtcg cgggtggcgg ggtagggcgt gcattcgtcg
     2581 aagatcatca cgatgtccga gttcagcacg ctctggatct gcatcgagat ctcgggcgtg
     2641 aggaagagct tcgcgccgtc gatcgggctg gcgaacttga cgccttcctc ggtgatcttg
     2701 cgcagcgcgc ccaggctgaa cacctggaag ccgcccgagt cggtgaggat gggcttgtcc
     2761 caggccatga agcggtgcag gccctggtgc gcgccgatga tgtccagccc cgggcgcagc
     2821 cacaggtgga aggtgttgcc caggcagatc tgcgcgccga tgtcggcgag catcgccggc
     2881 gtcatcgcct tgaccgtgcc gtaggtgccg accggcatga acaccggggt ctcgaccacg
     2941 ccgtgggcga gggtcaggcg gccgcggcgg gcgccgccgt tggtggtgag gagttcaaac
     3001 tgcatcgtcg ttgttgtcgt tctcggattc gttcttgcgg gtgatgaaca tcgcgtcacc
     3061 gtagctgaag aagcggtagc gctgttcgac cgcgtgggca taggcgcggc ggatgctgtc
     3121 catgccggcg aaggcggaga ccagcatcat cagggtggat ttgggcaggt ggaagttggt
     3181 gaccagcgca tccaccacct ggaagcggaa gccggggagg atgaagatct cggtctcgcc
     3241 gctgccggcc tcgagcgggc cgtcctgtgc tgccgcctcg agtgcgcgca tgctggtggt
     3301 gccgaccgcg atcacgcggc cgccggcggc gcgggtggcg gcgatggcat caacggtttc
     3361 ctgcgggatc acgtagcgct cgcggtgcat gcggtgttcg ccgaggtcgt ccacccgcac
     3421 cggctggaag gtgccggcgc cgacatgcag ggtgagccag gcgcacttcg ccccacgctc
     3481 tgcgatgcgc gcgagcagcg cgtcgtcgaa gtgcaggccg gcggtgggcg cggcgaccga
     3541 gccgggctcg cgtgcgtaga ccgtctggta gcgcgactcg tcggcttcgc cggcggcgcg
     3601 ctggatgtag ggcggcagcg gcagcttgcc gtggcgctcg agcagtacga gcaggtcctc
     3661 gccgaccgga aagcgcaggt ggaagaactc gccgacgcgg ccgagcacct cgacctcgaa
     3721 ggcgtccgcc agccgcagcc ggctgccggt cttcggcgac ttgctcgcgc gcacctgggc
     3781 gagcgcctcg tgtggcccga ccggtcgctc gatcagcacc tcgacctggc cgccgctgtc
     3841 cttgacgccg tgcagtcggg cgtggatgac gcgggtgtcg ttgaagacga gcaggtcgca
     3901 gggatcgatg cgctcggcga gggcggagaa caccgcgtcg gtgagccgcg gcgcggcatt
     3961 ctcctgcggc tccaccacca gcaggcggct ggcgctgcgc tcgggcagtg gtgcctgggc
     4021 gatcagctcg gcgggcaggg tgtagtcgaa gtcggcgagg gtgagggaca tcgtgtcgtg
     4081 ttcggtggag attgttctgg tccggccggc gcgggcgacg gctcgcttgc cgccccggct
     4141 cgtgttcggg gataatgcgc gtcccgtgcc gggatggcgg aatcggtaga cgcagcggat
     4201 tcaaaatccg ccgccgcaag gtgtgtgggt tcgagtccca ctctcggcac cagtttctgg
     4261 ctccgtcggt cgatcatcga ccgcagggct ttcttcgatg ggcgcggcgt tcgaccacgc
     4321 ccgtcccagc gtcgttcgcg gcggagttct ccgttcgctt ttccgccccc agcttcccgc
     4381 aacccgatcg gccgcttccg tccctgcgca ggccggaccc cggtgtcgcg tccccgcgcc
     4441 cgtttccggc ccgcgattct ggagcgctcc ggggcgaaaa tcaaatcagg cgaagttctg
     4501 cttcgcgtgc gcgccctcgc tgatcgcgcg caccgcgggg tgggtcagcc tgcgctcgac
     4561 cgagatcgcg taataggttt cggtgacccc tttcgcgtcc cccaggtgca ccagcccgcc
     4621 ctggcggcag agctgctcgc cgaccagtga tgcgctcggg aagatgcccg cgccggcctc
     4681 ggcgaaggcg cgcatcagcg cgctgtcgtc gaactcgccg acgatgcgcg gacgcagccc
     4741 ggcggcctcg atccagcgca gcagcggccc gcgcacgctg gcctcgaccc ccggcagcag
     4801 cagcggtgcg ccgtcgagat gggcgggaaa gtcgccggcg aggcgggcgg cgagcgcggg
     4861 cgcggcgtag aagccgatgg tcgactcgcc gagcgcatgg ctgaagccgc gcacgtccat
     4921 ggcgggcggc agcgggctgt cggcgaggac cacgtcgagt ttgtggatgg cgagctcgcc
     4981 gagcagggcg tcgaacttgc cctcgcggca gacgatgcgc atcggctcgg ggaggtccat
     5041 cgacggcgcc agcagcagcc acgcgatcgc cttcggcacc acgtcggcga tgcccacgcg
     5101 gaagggcacg gcacgcccgg tggcgcggct ctgcagcgct tcctcgagct cgttgccgag
     5161 gcggaagatc tcctcggcgt agtccagcac catgcgtccg gtctcggtca gcaccaggcc
     5221 gcggccctgg cgcttgaaga ggttcacgcc gagatcggtc tccagcgtgg cgatctggcc
     5281 cgacagggtc tgcggcgcca gcccggaacg ttccgccgcg cgcacgatcc cacccgcacg
     5341 ggccacggtc cagaaatgat ggagctgctt gtagttcagc atgggtcgcc tccggcgcac
     5401 gcgattcgat acttcggaaa aatcggattc aaattctgct gaaccgagat tctatcgaac
     5461 agtctgagcg gtagtatcca ccggagcaca gggcccgatg gatccgtgca acgaaaacga
     5521 aggagactgg acatgcgtat cgatctgcat tgcgacggtg ttgagaccgc ccccggcctg
     5581 cgcgactacg tggcgcagcg gatgcgttcg tcgatcggcc gcttccgcga ccacatccag
     5641 tgggcgcgcg tgaaggtcgc cgcggtgaat ggtccggagg gcggcaccga caagcgctgc
     5701 gtcgtgcagc tgcgcctgcg caacctgccc gacgtggtgt tcgcgatcac ccagctcgac
     5761 gtgcgagccg cggtggacga ggcggccgac cgggttgccc gcgtgctcgc ccagcgcgtg
     5821 cgccgccacc agcgcgggcc ggcgatggcc gcgatcccgg catgattctt tcgtagtccc
     5881 tgcagcaaac ccccggtcgt ccgcccgttc ggcgccggtt ccaaaacaaa tcgacgatcc
     5941 cactggagga cttccaccat ggaaaaccgc atcagcaccc tgggccgggc cgaagtctcg
     6001 gtcctgcaga ccaacaaggt catccgcaac acctacatgc tgctgtcgct gacgctggcc
     6061 ttctcggcgc tgaccgccgg cctgtcgatg gcgatgggcg cgccgcgcct gggcatcctg
     6121 atcacgctgg tcggctactt cggcctgctg ttcgccacca ccaagttccg cgacagcagc
     6181 cttggcatcg tgttcgtgtt cgcgctgacc ggcttcatgg gcttcaccct cggcccgatc
     6241 atctcctcgt acctggcgct ccccaacggc agctcgatcg tgatgcaggc gatggccggc
     6301 accgcggcga tcttcctcgg cctgtcggcc tacgcggtga cgaccaagaa ggacttctcc
     6361 ttcatgggcg gcttcctgat ggtcggcatc ctggtggcct tcctcgccgg cctgggcgcg
     6421 atcttcttcg agatcccggc gctgtcgctg accgtctcgg ccgccttcgt gctgctgatg
     6481 tctggcctga tcctgttcga gaccagcaac atcatccacg gcggcgagac caactacatc
     6541 atggccacgg tgtcgctgtt cgtgtcgatc ttcaacctct tcaccagcct gctgcacctg
     6601 ctgggtttcg ccaacaacga ctgacccgga tcgcccgccg cggcgggcga catccgcaaa
     6661 ggggcggtgg ccgcgaggcg ccgccccgtt cttttgtgcg cacgccgcgc ttttgcgctg
     6721 cagcacgcgc gccgtacgcg gccgggcggc tggcgttaca atggcgcaca tttttgactg
     6781 ggacagcccg ggatgaagac cacctttctt gatttcgaaa cggcgatctc cgaactcgag
     6841 gagaagatcg accagctccg cttcgtccag gacgatccag ccgtcgatat ctccgacgag
     6901 atcaagcggc tcgaggccaa gagccagtcg ctgaccaagg acctctacgc caagctcagc
     6961 ccctggcaga tcgcccaggt cgcgcgccac ccgcagcgcc cctacacgct ggactatgcc
     7021 agcctgatgt tcaccgactt ccacgagctg cacggcgatc gcagctatgc cgatgaccgc
     7081 gccatcgtgg gcgggctggc gcgcttcaac ggccaggcct gcgtggtgat cggccaccag
     7141 aagggccgcg acaccaagga aaagatcgcg cgcaacttcg gcatgccgcg ccccgagggc
     7201 taccgcaagg cgatgcgcct gatgaagctg gcggagaagt tcgcgctgcc ggtgtttacc
     7261 ttcgtcgaca ccccgggcgc ctatcccggc atcggcgccg aggagcgcgg ccagtccgag
     7321 gcgatcggcc acagcatcta cctgatgtcg gagctcaaga ccccgatcat cagcaccatc
     7381 atcggcgaag gcggctcggg cggtgcgctc gcgatcgcgg tggcggaccg cgtgctgatg
     7441 ctgcagtact ccacctactc ggtgatctcg cccgagggct gcgcctccat cctgtggaag
     7501 agcgcggaga aggccgccga cgcggccgag accatgggca tcaccgcggc acgcctgaag
     7561 tcgctcgagc tggtcgacaa ggtgatcgac gagccgatcg gtggcgccca ccgcgaccac
     7621 cgcgccatgg ccgccacgct caagcgtgcc ttggccgacg cgctgcgcga gctcgaggcg
     7681 ctgtcgccct ccgaactcgt cgagcagcgc taccagaagc tgatgagcta cggccgctac
     7741 aaggagaagg cggcctgag
//
LOCUS       DAOTIN010000147         7726 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_11344_length_7726_cov_7.934298, whole genome shotgun sequence.
ACCESSION   DAOTIN010000147 DAOTIN010000000
VERSION     DAOTIN010000147.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 7726)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 7726)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7726
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_11344_length_7726_cov_7.934298"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(66..845)
                     /gene="hyi"
                     /locus_tag="P5537_15100"
     CDS             complement(66..845)
                     /gene="hyi"
                     /locus_tag="P5537_15100"
                     /EC_number="5.3.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxypyruvate isomerase"
                     /protein_id="HRV79413.1"
                     /translation="MPKFNANLTMLFNEVPFLDRFQAAAEAGFKGVEFLFPYAFDKDA
                     IAERLDQHGLVQVLHNLPAGDWDAGERGIACHPDRVGEFRDGVGRAIEYATALGCKQL
                     NCLAGIAPAGVDAEKVHATFVANLRFAAARLEEAGIRLLVEPINTFDIPGFHLNRTAQ
                     AIALIEEVGSPNLWLQHDVYHMQRMEGELANTIARHLPRIAHMQIADTPGRHEPGTGE
                     INYAWLFRFIDQLGYDGWIGCEYKPAAGTREGLGWIAALAG"
     gene            complement(920..2695)
                     /gene="gcl"
                     /locus_tag="P5537_15105"
     CDS             complement(920..2695)
                     /gene="gcl"
                     /locus_tag="P5537_15105"
                     /EC_number="4.1.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009028 - tartronate-semialdehyde synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate carboligase"
                     /protein_id="HRV79414.1"
                     /translation="MARMRAVDAAAAVMRKEGVSTVFGVPGAAINPLYSAMQKDGGFR
                     HILGRHVEGAAHMAEGYTRANPGNIGVCIGTSGPAGTDMITGLYSASADSIPILCITG
                     QAPRARLHKEDFQAVDIESIAKPVTKWAVTVREPALVPRVFQQAFHLMRSGRPGPVLI
                     DLPFDVQMAEIEFDIDTYAPLPAYKPAATRAQAEKAMAMLAAAERPLIVAGGGVINAD
                     AAARLQEFAELTGVPVIPTLMGWGTIPDDHPLMAGMVGLQTSHRYGNATMLAADFVFG
                     IGNRWANRHTGSVEVYTRGRKFVHVDIEPTQIGRVFGPDYGIVSDAGAALDRLLEVAR
                     EMKAAGRLPDRSAWVAECQERKRTMQRKTHFDQVPMKPQRVYEEMNLAFGKDTCYVST
                     IGLSQIAAAQFLHVYKARHWINCGQAGPLGWTIPAALGVCAADPGRRVVAISGDYDFQ
                     FMIEELAVGAQFKLPYLHVLVNNAYLGLIRQSQRGFDMDFCVQLAFENINAPQTEGYG
                     VDHVGVVEGLGCKAIRVRTPEEIQPAFAQAQQWMEEFRVPVVVEIILERVTNISMGTE
                     IDAINEFEALAEKGADAPTAISMLD"
     gene            2919..3824
                     /locus_tag="P5537_15110"
     CDS             2919..3824
                     /locus_tag="P5537_15110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001216 - DNA-binding transcription
                     activator activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HRV79415.1"
                     /translation="MDRHTELRSFVLVAEKGSFAGAALVEGVTPVVMGRRLDALEKRL
                     GVKLMHRSTRGLALTELGEQLLDQSRALLREFDELERAVGAGRDVVRGHLVVSAPAAF
                     GRRHVAPHATAFKALHPELRMSFNFTDSVVDLVREGYDMAIRIGEVTDPNYVALRLFP
                     NRRVVCGTPDYFERHGIPRQPEDLARHNCLAFNLAGGQQRGWTFQREGRLFAVRADGD
                     LACNDGELLYGWVKQGLGVGWRSTWEIQAELKRGELVTVLDEFAVPSYDIQAVYPQQR
                     YLPAKVRRFIEHLRESYNRPGYWEE"
     gene            complement(3836..4741)
                     /locus_tag="P5537_15115"
     CDS             complement(3836..4741)
                     /locus_tag="P5537_15115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HRV79416.1"
                     /translation="MKDHQLRALVQVAESGSIRAAARAMNLSQSALTKALRELEEDVG
                     AELLQRSYKGIGFTPEGCALLGRARLVLATLERAREEIRLMRGGAGAHVKVAITPLVS
                     STVLPAVLAAYRRLQPDAALTFDEGLLVQALPGLIEGRIDFAIALASPQDLPYEIEFE
                     TLADIEAVPFARSTHPLAGASDWAALSDADWVLNLSAGSQSMNLVDWLAHRGIAPPHR
                     ITHCSSPFLIVELARRNDLLGYGPKVLITDPLVGAGLRTLAIEPLPPTMPLGLLSLRG
                     VPLGSAAKKLAELFRRELRSRLPRP"
     gene            4852..6066
                     /locus_tag="P5537_15120"
     CDS             4852..6066
                     /locus_tag="P5537_15120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20 aminoacylase family protein"
                     /protein_id="HRV79417.1"
                     /translation="MTNAAVLFEPDVEGMTAWRRAIHRHPELGFEEHATSTLVAERLR
                     AWGYEVHTGIAVTGVVGVLRVGDGSGRTIGLRADMDAIPVQEMTGLPWASTVPGKMHG
                     CGHDGHTAMLLGAAQALAARAKSGALPGNGTLVLIFQPAEELGGGGGARRMLDEGLFE
                     RFPCDAIFGMHNFPGIPVGEVHVRTGAFMASSDKVGIRFVGRGGHGGMPHMAVDPTLP
                     AAATVLGLQSIIGRNVNPNHAAVISVGRIEAGSAYNVIGEAAELELSVRALDPGARDL
                     IEHRIRELAEHQARAYGCTSEIRYERGYPVLINAAEPTAFAVEVARALFGAENVVADA
                     QPLTGSEDFAFLLERVPGSYLLVGNGDNGHADGKWAGGCMVHNPHYDFNDACLAVGAR
                     LWIGLVEQYFQN"
     gene            6087..7124
                     /locus_tag="P5537_15125"
     CDS             6087..7124
                     /locus_tag="P5537_15125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HRV79418.1"
                     /translation="MKLSKLFATLSAGFVLATGAGLPAAQAATTLNMSSWVSPTHFLT
                     PEVFQPWIEDVKRVTEGRVDVRILPKPVGGPAQHWELARKGVADITWGNFTYEPDRFK
                     AVWFSEMPFTGTNAEASSLALWETYEKYLAGKPAFEGVVMLGVGLFGGGQIHHGSKNI
                     VEPDDLKNQKVRMGGPIQKRLLEDLGAVPVAGPGPKAYELLESGVVDASLHTIESVIN
                     FRVEDKLKHHTIVPGGFYDASFFIAINEGKWNKLSEADRKAIMSVSGEKLSRLWGQRF
                     DAQNKAGEAKLRGEGHNFSEPSKALFERIGAVRQRMLADWAAEGPSYGVDKPMEMLEF
                     FEQRYKAHAGK"
     gene            7184..7681
                     /locus_tag="P5537_15130"
     CDS             7184..7681
                     /locus_tag="P5537_15130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015740 - C4-dicarboxylate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HRV79419.1"
                     /translation="MDAYLSRIRQLVESLLILTLLGMVLLTFADVIGRRLFGAPVFGA
                     HDATEHLMAIMVFCGLPLLTAARGHLAVDLFDKYLMTPAMAWWHRLIALLMTLVLLLI
                     AYEFFNAAIEAGQIQEISQALSIPRSGMYAFIAFTSLLSALAALLGCFGAPASHPHAT
                     EEYAK"
BASE COUNT         1173 a         2630 c         2663 g         1260 t
ORIGIN      
        1 cggctgccgc cgctcctaca gggtcccgca agccgcgccg gttcatgtag gagcgaacgg
       61 cgccctcagc cggcgagcgc cgcgatccag cccaggcctt cacgggtgcc ggctgcgggc
      121 ttgtattcgc agccgatcca gccgtcgtag ccgagctggt cgatgaagcg gaacagccag
      181 gcgtagttga tctcgcccgt gcccggctcg tggcggcccg gggtgtcggc gatctgcatg
      241 tgggcgatcc tgggcaggtg cctggcgatg gtgttggcga gctcgccctc catgcgctgc
      301 atgtgataga cgtcgtgctg cagccacagg ttgggcgagc cgacctcctc gatcagcgcg
      361 atcgcctgcg cggtgcggtt gaggtggaag cccgggatgt cgaaggtgtt gatcggctcg
      421 accagcaggc ggatgcccgc ttcctccagc ctggcggcgg cgaagcgcag gttggcgacg
      481 aaggtggcgt gcaccttctc cgcatccacg ccggccgggg cgatgccggc gaggcaattc
      541 agctgcttgc agccaagcgc ggtcgcgtac tcgatggcac gcccgacccc gtcccggaac
      601 tcgccgacgc ggtccggatg gcaggcgatg ccgcgctcgc ccgcgtccca gtcacccgcg
      661 ggcaggttgt gcagcacctg caccaggccg tgctggtcga gccgttccgc gatcgcatcc
      721 ttgtcgaagg cgtaggggaa gaggaactcc acgcccttga agccggcctc cgccgccgcc
      781 tggaagcggt cgaggaaggg cacttcgttg aacagcatgg tgagattggc gttgaacttc
      841 ggcatgtcgg tgtctccggt tttcagttgc ggtcgagggc ggcctgcggg ggcgggtgcg
      901 ccgctcccgc gcgctgcgtt caatcgagca tcgagatcgc ggtcggggcg tcggcaccct
      961 tttcggcgag cgcctcgaac tcgttgatgg cgtcgatctc ggtgcccatc gaaatgttgg
     1021 tgacgcgctc gaggatgatc tcgaccacca ccggcacgcg gaattcttcc atccactgct
     1081 gcgcctgcgc gaaggcgggc tggatctctt ccggcgtgcg cacgcggatc gccttgcagc
     1141 ccaggccctc gaccacgccg acgtgatcga cgccgtagcc ttcggtctgg ggcgcgttga
     1201 tgttctcgaa cgcgagctgc acgcagaaat ccatgtcgaa gccgcgctgc gactggcgga
     1261 tgaggccgag gtaggcattg ttcaccagca cgtgcaggta gggcagcttg aactgcgcgc
     1321 ccaccgccag ctcctcgatc atgaactgga agtcgtagtc gcccgagatc gccaccacgc
     1381 ggcgcccggg gtcggccgcg cacactccca gtgccgcggg aatcgtccac ccgagcgggc
     1441 cggcctggcc gcagttgatc cagtggcgcg ccttgtacac gtgcaggaac tgcgcggcgg
     1501 cgatctgcga caggccgatg gtgctgacgt agcaggtgtc cttgccgaag gcgaggttca
     1561 tctcctcgta cacccgctgc ggcttcatcg gcacctggtc gaagtgcgtc ttgcgctgca
     1621 tcgtgcgctt gcgctcctgg cactcggcca cccaggcgct gcggtcgggc agccggcccg
     1681 cggccttcat ctcgcgcgcc acttcgagca ggcggtcgag cgcagcgccg gcatccgaca
     1741 cgatgccgta gtccggcccg aacacgcggc cgatctgcgt cggctcgatg tccacatgca
     1801 cgaatttgcg ccccctggtg tacacctcga ccgagccggt gtggcggttt gcccagcggt
     1861 tgccgatgcc gaacacgaag tccgcagcca gcatcgtggc gttgccgtag cggtgcgagg
     1921 tctgcaggcc gaccatgccg gccatcagcg ggtggtcgtc ggggatcgtt ccccagccca
     1981 tcagggtcgg gatcaccggc acgccggtca gttcggcgaa ctcctgcagg cgggccgccg
     2041 cgtcggcgtt gatcacgccg ccgccggcga cgatcagcgg gcgctcggcg gcggcgagca
     2101 tggccatcgc cttctcggcc tgggcgcggg tggcggccgg cttgtaggcg ggcagcggcg
     2161 cgtaggtgtc gatgtcgaac tcgatctcgg ccatctgcac gtcgaagggc aggtcgatca
     2221 gcaccgggcc agggcggccc gagcgcatga ggtggaaggc ctgctggaac acccgcggca
     2281 ccagcgccgg ctcgcgcacc gtcaccgccc acttggtcac cggcttggcg atcgactcga
     2341 tgtccaccgc ctggaagtct tccttgtgca ggcgggcgcg cggtgcctgg ccggtgatgc
     2401 acaggatggg gatggagtcg gccgaggccg agtacaggcc ggtgatcatg tcggtgccgg
     2461 ccgggcccga ggtgccgatg cacacgccga tgttgcctgg attggcgcgc gtgtagcctt
     2521 cggccatgtg cgcggcgccc tcgacgtggc ggccgaggat gtggcggaag ccaccgtcct
     2581 tctgcatcgc cgagtacagc gggttgatcg cggcgccggg cacgccgaac accgtgctca
     2641 cgccttcctt gcgcatcacc gcggctgcgg catcgactgc tctcatgcgg gccatcttgt
     2701 gtctcctgtc gggaatgttg ttgaactcga tggacgcagc atacggagcc ggcggggagc
     2761 gatgaagggg cgtggaaatc cgttctgaca atacttaaag tatcggctga agcagacaaa
     2821 ggcgaagaag acgccgtatt tgcggcggct tatggggctt atccgtattc ggaatatctt
     2881 ccaggtatct tttagcccct ttgacggaga gcaggcgaat ggatcgtcac accgagctgc
     2941 gcagcttcgt gctggtggcc gagaagggca gctttgccgg cgcggcgctg gtcgagggcg
     3001 tcacgccggt ggtcatggga cggcggctcg acgcgctgga gaaacgtctc ggcgtcaagc
     3061 tgatgcaccg ctcgacgcgc ggcctggcgc tgaccgagct cggcgagcag ctgctcgacc
     3121 agagccgcgc gctgctgcgc gagttcgacg agctcgagcg cgcggtcggc gccgggcgcg
     3181 acgtggtgcg cggccacctg gtggtgtcgg cgcccgcggc cttcggtcgc cgccacgtcg
     3241 ccccgcacgc gaccgcgttc aaggcgctgc acccggagct gcgcatgtcc ttcaacttca
     3301 ccgacagcgt ggtcgacctg gtgcgcgagg gctacgacat ggcgatccgc atcggcgagg
     3361 tcaccgaccc caactacgtg gcgctgcgcc tgttccccaa ccgccgcgtg gtgtgcggca
     3421 cgcccgacta cttcgagcgc cacggcatcc cgcgccagcc cgaggacctc gcccgccaca
     3481 actgcctcgc cttcaacctc gccggcggcc agcagcgcgg ctggaccttc cagcgcgagg
     3541 ggcggctgtt cgcggtccgt gccgacggcg acctcgcctg caacgacggc gagctgctgt
     3601 acggctgggt gaagcagggg ctgggggtgg gctggcgctc gacctgggag atccaggccg
     3661 agttgaagcg cggcgagctg gtcaccgtgc tcgacgagtt cgccgtgccg agctacgaca
     3721 tccaggcggt ctatcctcag caacgctacc ttccggccaa ggtgcgccgc ttcatcgagc
     3781 acctcaggga gagctacaac cggccggggt actgggagga gtgaggcgcg cggtgtcagg
     3841 ggcggggcag gcgggaccgc agctcgcggc ggaacagctc ggcgagcttc ttcgccgcgc
     3901 tgccgagcgg cacgccgcgc aggctcagca ggcccagcgg catcgtcggg ggcagtggct
     3961 cgatcgccag cgtgcgcagc ccggcgccca cgagcgggtc ggtgatcagg accttcgggc
     4021 cgtagccgag caggtcgttg cgccgcgcca gctccacgat caggaagggc gaggagcagt
     4081 gggtgatgcg gtgaggcggg gcgatgccgc ggtgcgcgag ccagtcgacc aggttcatgc
     4141 tctggctgcc tgcactgagg ttgagtaccc agtcggcgtc gctgagcgcc gcccagtcgc
     4201 ttgcgccggc cagcgggtgg gtgctgcggg cgaagggcac cgcctcgata tcggcgaggg
     4261 tctcgaactc gatctcgtag ggcaggtcct gcggcgaggc gagcgcgatc gcgaagtcga
     4321 tccggccctc gatcaggccg ggcagcgcct gcaccagcag gccctcgtcg aaggtgagcg
     4381 cggcgtccgg ctgcaggcgg cgataggcgg cgagcacggc ggggagtacg gtcgaggaca
     4441 ccagcggggt gatcgccacc ttcacgtgcg ctccagcgcc gccccgcatc aggcggatct
     4501 cctcgcgcgc acgctccagc gtggccagca ccagccgggc gcggccgagc agggcgcagc
     4561 cctcgggcgt gaagccgatg cccttgtagc tgcgctgcag cagttcggcg cccacgtcct
     4621 cctcgagctc tcgcaaggcc ttggtgagcg cgctctgact caggttcatc gcccgcgcgg
     4681 cggcgcggat cgagccgctt tccgccactt gcacgagcgc acgcaattgg tggtccttca
     4741 tgctgtttcg tgatcccttc gggttgtcac ccacgaaaaa atatcgcctt acggtgtgag
     4801 ctgcaagttt ctaatatctg gacatgaact aattctatgg aggagagcca gatgacgaac
     4861 gctgcagtac tgttcgagcc ggacgtggag ggcatgacgg cctggcgccg tgccatccat
     4921 cgtcatcccg agctcggctt cgaggagcac gccaccagca cgctggtcgc cgagcggctg
     4981 cgcgcctggg gctacgaggt gcacaccggc atcgccgtca ccggcgtggt gggcgtgctg
     5041 cgcgtgggcg acggcagcgg gcgcacgatc ggcttgcgcg ccgatatgga cgccatcccg
     5101 gtgcaggaga tgaccggcct gccgtgggcg agcaccgtcc ccggcaagat gcacggctgc
     5161 ggccacgacg gccacaccgc gatgctgctc ggtgccgccc aggcgcttgc cgcgcgtgcg
     5221 aaaagcgggg cgctgccggg caacggtacc ctggtgctga tcttccagcc ggccgaggaa
     5281 ctcggcggcg gcggcggcgc gcggcgcatg ctcgacgaag gcctgttcga gcgctttccc
     5341 tgcgatgcga tcttcggcat gcacaacttc ccgggcattc cggtcggcga ggtccatgtg
     5401 cgcacgggcg ccttcatggc ctcctcggac aaggtgggga tccgcttcgt cggccgcggc
     5461 gggcacggcg gcatgcccca catggcggtc gatccgaccc tgccggcggc ggcgaccgtg
     5521 ctcgggctgc agtccatcat cggccgcaac gtcaatccca accacgccgc ggtgatcagc
     5581 gtcggccgca tcgaggcggg ctcggcctac aacgtgatcg gcgaggccgc cgaactcgag
     5641 ctcagcgtgc gtgcgctcga tcccggcgcg cgcgacctca tcgagcatcg tatccgcgaa
     5701 ctcgccgaac atcaggcgcg cgcctacggc tgcaccagcg agatccgcta cgagcgcggt
     5761 tatccggtgc tgatcaacgc cgccgagccc accgccttcg cggtcgaggt cgcgcgcgcg
     5821 ctgttcggcg ccgagaacgt ggtggccgac gcccagcccc ttacgggcag cgaggacttc
     5881 gccttcctgc tcgagcgcgt gcccggcagc tacctgctcg tcggcaatgg cgacaacggc
     5941 cacgccgacg gcaagtgggc cggcggctgc atggttcaca acccgcacta cgatttcaac
     6001 gatgcctgcc tcgcggtggg cgcccggctg tggatcggcc tggtcgagca gtacttccaa
     6061 aactaaatac ccctgaagga gacaccatga aactcagcaa gctcttcgcc accctgtccg
     6121 ctggcttcgt cctcgccacc ggcgccggcc tgcccgccgc ccaggccgcc accaccctga
     6181 acatgtcgag ctgggtgtcg cccacccact tcctcacccc cgaggtcttc cagccctgga
     6241 tcgaggacgt caagcgcgtc accgaaggcc gtgtcgacgt gcgcatcctg cccaagccgg
     6301 tcggtggtcc cgcccagcat tgggaactgg cgcgcaaggg cgtggccgac atcacctggg
     6361 gcaacttcac ctacgaaccc gatcgcttca aggccgtgtg gttctcggag atgcccttca
     6421 ccggcaccaa cgccgaggcg tcctcgctgg cgctgtggga gacctacgag aaatacctcg
     6481 ccggcaagcc ggccttcgag ggcgtggtca tgctcggcgt cgggctcttc ggtggcggcc
     6541 agatccacca cggcagcaag aacatcgtcg agcccgacga cctcaagaac cagaaggtgc
     6601 gcatgggcgg cccgatccag aagcgcctgc tcgaggacct cggcgcggtg ccggtcgccg
     6661 gccccggccc caaggcctat gagctgctcg agagcggcgt ggtcgatgcc tcgctgcaca
     6721 ccatcgagtc ggtgatcaac ttccgcgtcg aggacaagct caagcaccac accatcgtcc
     6781 ctggcggctt ctacgacgcc agcttcttca tcgccatcaa cgagggcaag tggaacaagc
     6841 tctccgaggc cgaccgcaag gcgatcatga gcgtgtcggg cgagaagctg tcgcgcctgt
     6901 ggggccagcg cttcgacgcc cagaacaagg ccggcgaggc caagctgcgc ggcgagggcc
     6961 acaacttcag cgagccctcg aaggcgctgt tcgagcgcat cggtgcggtg cgtcagcgca
     7021 tgctcgccga ctgggcggcc gaaggcccga gctacggggt cgacaagccg atggagatgc
     7081 tcgagttctt cgagcagcgc tacaaggccc acgccggcaa gtgatcgccc gctgatccgg
     7141 gaagtggccg gctccggccg gccacgccca catggagaat cacatggacg cgtatctgtc
     7201 ccgtatccgc cagctcgtcg agtcgctgct catcctcacg ctgctgggca tggtcctgct
     7261 caccttcgcc gacgtcatcg gtcgccggct gttcggcgcc cccgtcttcg gcgctcacga
     7321 cgccaccgag cacctgatgg cgatcatggt gttctgcggc ctgccgctgc tgaccgccgc
     7381 gcgcggacac ctcgcagtgg acctgttcga caagtacctg atgacgcccg ccatggcgtg
     7441 gtggcaccgg ctcatcgcgc tgctgatgac cctcgtgctg ctgctgatcg cctacgagtt
     7501 cttcaacgcc gcgattgagg cgggccagat ccaggagatt agccaggcgc tgtcgatccc
     7561 gcgtagcggc atgtacgcct tcatcgcctt cacctcgctg ctgtccgccc tggcggcgct
     7621 gctgggctgt ttcggcgccc ccgcctcgca cccccacgcc accgaggagt atgccaaatg
     7681 accgtcggac ttctttccct gttggccgtc ctggtgctgg ccttcc
//
LOCUS       DAOTIN010000148         7702 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_11396_length_7702_cov_7.971361, whole genome shotgun sequence.
ACCESSION   DAOTIN010000148 DAOTIN010000000
VERSION     DAOTIN010000148.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 7702)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 7702)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7702
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_11396_length_7702_cov_7.971361"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..826)
                     /locus_tag="P5537_15135"
     CDS             complement(<1..826)
                     /locus_tag="P5537_15135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase, T2SS/T4P/T4SS family"
                     /protein_id="HRV79420.1"
                     /translation="MAATSKPALSGFARALIQHGHLKEADAVACTLQAGETATAFILE
                     VANRGLMSCAAMARFAAETFGYPLLDLAAFDAAMFAREAVDRKLLAKHQVAPLAKRQN
                     RITLATADPSNLRALDEIRFQTGLQLELVIVEADKLKRVVEALSESAADTLKELTGEA
                     FDMDLLQQDSPTQSRDEEEANEVDDAPVVKFIQKVLIDAINEGASDVHFEPYEKFYRI
                     RVRTDGILRDIAQPPLVLKEKIAARIKVISRLDISEKRVPQDGRMKLVLSKNKAIDF"
     gene            complement(915..2195)
                     /locus_tag="P5537_15140"
     CDS             complement(915..2195)
                     /locus_tag="P5537_15140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HRV79421.1"
                     /translation="MTDLTLTLQFVALVVLLTLSGCFSMSETVMMAANRYRLRALASQ
                     GNRGAGLALDLLARTDRLLGVILLFNNLVNTGAATLVSVITLELFGNESWALGIATLL
                     VTFAILVFSEITPKVIGANHADRLAPFVAYPLTGLLRASYFAVWFINLFSRGLLNLMR
                     LQPKEEAQSALSVEELRAMVIDSGQYIPHKHRSMLLNLFDLESITVEDVMTPRGAIES
                     IDLSDPEDVVRRQIATSFHTRLAVYDGDSEHVIGVLHQRKLLGSTLEDDFSVERIREL
                     LARPYFVPSDTPLYSQIQFFQENQQRLGFVVDEYGEILGLITLEDIIEELIGKFTTST
                     PDVGDRMHWGEDGSVLVDGTSNLRELNRRLELALPTDGPKTLNGLILEHLQDIPETGV
                     SMKIADTPIEVVQTQDRMVRTARIFRPLIDDTEQ"
     gene            complement(2280..3110)
                     /gene="ccsA"
                     /locus_tag="P5537_15145"
     CDS             complement(2280..3110)
                     /gene="ccsA"
                     /locus_tag="P5537_15145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis protein CcsA"
                     /protein_id="HRV79422.1"
                     /translation="MRTILLHLLPASLYAGLGVFFWRTCMTRGSALQPRRECMSMRER
                     LLLLGAIVAHGAALHLAIFPGSEMRFGFGVAVSLMVWLAVCFYWVETLYTRLDGLHAA
                     VMPAGAIGSLVPMLFPGDHVLANATSPAFRAHFVVAMLAYSLFTLAALHAMLMAVAGR
                     QLHNARFSRLLSGLPPLLTMEALLFRLISIAFVLLTLTLASGLLFSETLFGQAFRVDH
                     KTIFAFVSWFLFGGLLLGRHLWGWRGRLALRWTLAGFVALMLAYVGSRFVIEVVLHRT
                     "
     gene            3159..4529
                     /gene="ffh"
                     /locus_tag="P5537_15150"
     CDS             3159..4529
                     /gene="ffh"
                     /locus_tag="P5537_15150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HRV79423.1"
                     /translation="MLDNLTQRLSKVVKTLRGQARLTEENIQEAMREVRMALLEADVA
                     LPVVKDFVAKVREKAVGQEVIGSLTPGQALVGVVHDELKALMGGAHEGLDLSTQPPAV
                     VLMAGLQGAGKTTTTGKLAKLLHEQQKKKVLVVSTDVYRPAAIEQLKTVAAQAGVGFF
                     PSETAQKPVDIAVAALDYARKHHIDVLLVDTAGRLAVDEAMMAEIQALHAAVKPIETL
                     FVVDAMLGQDAVNTARAFNEALPLTGVVLTKLDGDSRGGAALSVRHVTGKPLKFAGVG
                     EKLSGLEPFHPDRMASRILGMGDILGLVEDARRGVDEEKAKAFAQKLKTGKGFDLDDF
                     KEQIAQMRKMGGLSSMMDKLPAQFAQAAGKLQGGAEEKAISRIEGIINSMTPLERAKP
                     EILKASRKRRIAAGAGVTVQEVNRLLNQFEQTQKVMKQFSKGGMNKMMRAMKGMMPGG
                     LPGMPR"
     gene            4543..5319
                     /locus_tag="P5537_15155"
     CDS             4543..5319
                     /locus_tag="P5537_15155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EI24 domain-containing protein"
                     /protein_id="HRV79424.1"
                     /translation="MKDILVAFGRAGRSLGRRDIFWHLLWPGLLSMVIWAGVAFYAWT
                     PVTEWLYATVSGWSFIGGWLSASETTAAIVLVLIQIATALLVVPLVYVTAAMLVATVA
                     LPLMLERVARIDYTDLEQRRGGSNLGSAWNSILAGVLFLIALVLSLPLWLIPGAGLLI
                     SVTLTGWLNQRAFGYDALMYHADRGELKRLREDWRPQMLLLGGGTALLAYVPVINLVA
                     PAFAGLAFVHYMLETLRRHRIQYGITVLDAEPGADLRKLK"
     gene            5316..6065
                     /locus_tag="P5537_15160"
     CDS             5316..6065
                     /locus_tag="P5537_15160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HRV79425.1"
                     /translation="MNFGALIIGDEILSGRRSDKHLAKLIELLGARGLKLSWARYAGD
                     DFDRLADTLRQTFATGDVVFSFGGIGATPDDRTREAAGAALGLELALHPEAEAEIRAR
                     FGAEITPERLQMGVYPVGSEIIPNSFNRIPGFSIRQHYFTPGFPVMAWPMVEWVLDTK
                     YAHLHHAEDYVEQAVTVWDAYEGQLIGLMRQVTADFPDTTLFSLPTIAAEGQRRSLEL
                     GMKGTAARVAAAMAVIKADLSARGLEWEDKA"
     gene            6062..6826
                     /locus_tag="P5537_15165"
     CDS             6062..6826
                     /locus_tag="P5537_15165"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family zinc-dependent metalloprotease"
                     /protein_id="HRV79426.1"
                     /translation="MSARAAASEEPHSLLVEGTRVDLVLRRSARRSFTLQVDHRGARV
                     SVPLRTPLGEVERFVHSHGSWLLDRLRARAQAPQPPRLEVAEGVRLPLFGRALVLRLV
                     SARAARWRAADGGEELLLPAGVDPQRALVRALRARALAWYRGRVEEFCHRLGVPVSAV
                     SLSSAATRWGSCSTRSGIRLHWRLIHLEPALIDYVVAHEVAHLAEMNHSPRFWAVVER
                     LYPDWRAARAALRRAAATLPVIATAASDRGRFAGED"
     gene            6852..7238
                     /gene="gloA"
                     /locus_tag="P5537_15170"
     CDS             6852..7238
                     /gene="gloA"
                     /locus_tag="P5537_15170"
                     /EC_number="4.4.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004462 - lactoylglutathione lyase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0051596 - methylglyoxal catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HRV79427.1"
                     /translation="MRILHTMLRVGDLERSLAFYTEVLGMRLLRRQDYPDGKFTLAFV
                     GYQDEAEAAVLELTHNWGVGKYELGTAYGHIALEVADAKKACDDIRARGGKVVREAGP
                     MKHGTTVIAFVEDPDGYKVELIERKG"
     gene            complement(7279..>7702)
                     /locus_tag="P5537_15175"
     CDS             complement(7279..>7702)
                     /locus_tag="P5537_15175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015436920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="HD domain-containing phosphohydrolase"
                     /protein_id="HRV79428.1"
                     /translation="ILLKPGRLTPEEFAVMKRHPQIGHDILKGSSSSILRLGATIALT
                     HHEKFDGSGYPHGLAGESIPIEGRIVAVADVFDALTSSRPYKPAWPMSRAISLLREGR
                     GSHFDPARVDALFRAWDQVLAVQSRYQDEPAEPVLPSC"
BASE COUNT         1227 a         2518 c         2782 g         1175 t
ORIGIN      
        1 ggaagtcgat cgccttgttc ttcgacagca cgagcttcat gcggccgtcc tgcggtacgc
       61 gcttctcgga gatgtcgagg cgcgagatca ccttgatacg cgcggcgatc ttctccttga
      121 gcaccagcgg tggctgggcg atgtcgcgca ggatgccgtc ggtgcgcacg cggatgcggt
      181 agaacttctc gtagggctcg aaatggacgt cggaggcgcc ctcgttgatc gcgtcgatca
      241 gcaccttctg gatgaacttg acgaccggcg cgtcatcgac ttcgttggct tcctcctcgt
      301 cgcgcgattg cgtggggctg tcctgctgca gcaggtccat gtcgaaggct tcgccggtca
      361 gctccttcaa ggtgtcggca gccgactcgg acaaggcttc gaccacacgc ttgagcttgt
      421 ccgcctcgac gatcacgagc tcgagctgca ggccggtctg gaagcggatc tcgtcgagcg
      481 cgcgcaggtt cgaggggtcg gcggtggcga gcgtgatgcg gttctggcgc ttggcaagcg
      541 gcgcgacctg atgcttggcg agcagcttgc ggtcgaccgc ctcgcgcgcg aacatcgccg
      601 catcgaaggc ggcgaggtcg agcagggggt agccgaaggt ctcggcggcg aagcgggcca
      661 tggccgcgca actcatcagg ccgcggttgg cgacctcgag gatgaaggcg gtcgcagtct
      721 cgcccgcttg cagggtgcac gcgaccgcgt ccgcctcttt caggtggcca tgctggatca
      781 gcgccctggc gaagccgctc agggccggtt tggaggttgc cgccatgcct tgctcgtgtc
      841 cggagtgcgg ccgatgttgc ccgccgcccc ccgccttgta aagatgcgtg cggccggcgc
      901 cggggcgtcg ggactcattg ctcggtgtcg tcgatcagcg gccggaagat gcgcgcggtg
      961 cgcaccatgc ggtcctgggt ctgcacgacc tcgatcggcg tgtcggcgat cttcatcgaa
     1021 acgccggtct cggggatgtc ctgcaggtgc tcgaggatga gtccgttgag cgtcttcggg
     1081 ccgtcggtgg ggagggcgag ctcgagccgg cggttgagct cgcgcaggtt ggacgtgccg
     1141 tcgaccagca cgctgccgtc ctcgccccag tgcatgcggt cgcccacgtc cggagtgctg
     1201 gtggtgaact tgccgatgag ctcctcgatg atgtcctcga gcgtgatcag gccgaggatc
     1261 tcgccgtatt cgtccaccac gaagccgagg cgctgctggt tttcctggaa gaactggatc
     1321 tgcgagtaga gcggggtgtc ggacggcacg aagtaggggc gcgcgaggag ctcgcggatg
     1381 cgttcgacgc tgaagtcgtc ctcgagcgtg ctgccgagca gcttgcgctg gtgcagcacg
     1441 ccgatcacgt gctcgctgtc gccgtcgtag accgccagcc gggtgtggaa gctggtggcg
     1501 atctggcggc gcacgacgtc ctcggggtcg gacaggtcga tgctctcgat cgcgccgcgt
     1561 ggcgtcatca cgtcctcgac cgtgatgctc tcgaggtcga agaggttgag cagcatgctg
     1621 cggtgcttgt gcgggatgta ctggcccgag tcgatcacca tcgcgcgcag ttcctcgacc
     1681 gacagcgccg actgggcctc ttccttcggt tgcaggcgca tcaggttcag cagcccgcgc
     1741 gagaacaggt tgatgaacca caccgcgaaa tacgatgcgc gcagcagtcc ggtgagcgga
     1801 taggcgacga agggcgcgag gcggtcggcg tggttggcgc cgatcacctt cggggtgatc
     1861 tcggagaaga cgaggatcgc gaaggtgacg agcagggtcg cgatgccgag cgcccagctc
     1921 tcgttgccga acagctcgag cgtgatcacg ctcaccaggg tcgcggcgcc ggtgttgacc
     1981 aggttgttga acagcaggat caccccgagc aggcggtcgg tgcgggcgag caggtcgagg
     2041 gcgagcccgg cgccacggtt gccctggctg gcgagcgcgc gcaggcggta gcggttggcc
     2101 gccatcatga ccgtctccga catcgagaag catcccgaca gggtcagcag cacgacgagg
     2161 gcgacgaact gaagcgtgag ggtgaggtcc gtcacgaggg gcggtggcga ggagaggggc
     2221 cccgagtatt ggagcccctc aggacgctgt caatacgcgc gaacgcccgc gcgccggact
     2281 caggtgcgat gcagcaccac ttcgatgacg aaacggctgc ccacgtaggc gagcatcagc
     2341 gccacgaaac cggccagggt ccagcgcagc gcgaggcggc cacgccagcc ccagaggtgg
     2401 cgaccgagca gcaggccgcc gaagaggaac caggacacga aggcgaagat cgtcttgtga
     2461 tcgacgcgga aggcctggcc gaagagcgtc tcggagaaca gcaggccgct cgccagcgtc
     2521 agggtgagca gcacgaaggc gatcgagatc aggcggaaca gcagcgcttc catggtgagc
     2581 aggggcggca ggccggagag caggcggctg aagcgcgcgt tgtgcagctg gcgcccggcc
     2641 acggccatca gcatcgcgtg cagggcggcc agggtgaaca ggctgtaggc cagcatggcc
     2701 accacgaagt gggcgcggaa ggccggggag gtggcgttgg cgagcacgtg gtcgccgggg
     2761 aacagcatgg gcacgaggct gccgatcgcg cccgcgggca tcaccgcggc gtgcaggccg
     2821 tcgagccggg tgtagagggt ctcgacccag tagaagcaca ccgccagcca gaccatcagc
     2881 gagaccgcga cgccgaagcc gaagcgcatc tcgctgccgg ggaagatcgc caggtgcagc
     2941 gccgcgccgt gcgcgacgat cgcgccgagc agcagcaggc gctcgcgcat gctcatgcat
     3001 tcgcggcgcg gctgcagcgc ggatccgcgc gtcatgcagg tgcgccagaa gaacacgccc
     3061 agaccagcgt aaagcgaggc ggggaggaga tgaagtagaa ttgtgcgcat acgtagccgc
     3121 agtttactcc aagtcacgcg cccaaggcct gccccaacat gctcgacaat ctgacccaac
     3181 gcctgtccaa ggtcgtcaag accctccgcg gccaggcccg cctgacggaa gaaaacatcc
     3241 aggaggccat gcgcgaggtg cgcatggcgc tgctcgaggc cgacgtcgcg ctgccggtgg
     3301 tgaaggactt cgtcgccaag gtcagggaga aggccgtcgg ccaggaggtg atcggctcgc
     3361 tgacccccgg ccaggctctg gtcggcgtgg tgcacgacga gctcaaggcg ctgatgggcg
     3421 gcgcccacga gggcctggac ctgtccaccc agccgcccgc cgtggtgctg atggccggcc
     3481 tgcagggcgc gggcaagacc accaccaccg gcaagctcgc caagctgctc cacgagcagc
     3541 agaagaagaa ggtgctggtg gtgtccaccg acgtctatcg cccggcggcg atcgagcagc
     3601 tgaagaccgt ggcggcgcag gcgggggtcg gcttcttccc ctccgagacc gcgcagaagc
     3661 cggtcgacat cgcggttgcc gcgctcgact acgcgcgcaa gcaccacatc gacgtgctgc
     3721 tggtcgacac cgctggccgg ctcgcggtgg acgaggccat gatggccgag atccaggccc
     3781 tgcatgccgc agtcaagccg atcgagaccc tgttcgtggt cgacgccatg ctcggccagg
     3841 atgcggtgaa caccgcgcgc gccttcaacg aggcgctgcc gcttaccggc gtggtgctga
     3901 ccaagctcga cggcgactcg cgtggcggcg cggcgctgtc ggtacgccac gtcaccggca
     3961 agccgctcaa gttcgccggc gtcggcgaga agctctccgg cctcgagccc ttccacccgg
     4021 accgcatggc cagccgcatc ctcggcatgg gcgacatcct cggcctggtc gaggacgccc
     4081 gccgcggcgt cgacgaggag aaggccaagg ccttcgcgca gaagctgaag accggcaagg
     4141 gcttcgacct cgacgacttc aaggagcaga tcgcccagat gcgcaagatg ggcgggctgt
     4201 cttcgatgat ggacaagctg ccggcgcagt tcgcccaggc ggcgggcaag ctgcagggcg
     4261 gggccgagga gaaggcgatc tcgcgcatcg agggcatcat caactcgatg accccgctcg
     4321 agcgcgccaa gcccgagatc ctcaaggcca gccgcaagcg ccgcatcgcc gccggcgccg
     4381 gggtgacggt gcaggaggtc aaccgcctgc tcaaccagtt cgagcagacg cagaaggtca
     4441 tgaagcagtt ctcgaagggg ggcatgaaca agatgatgcg ggcgatgaag ggcatgatgc
     4501 cgggcggtct gccgggcatg ccgcgctgag ggggacggac gcatgaagga catcctcgtc
     4561 gccttcgggc gcgccggtcg cagcctcggg cggcgcgaca tcttctggca cctgctgtgg
     4621 cccggcctgc tttccatggt gatctgggcc ggcgtggcgt tctacgcatg gacgccggtc
     4681 accgagtggc tgtacgccac ggtgagcggc tggtccttca tcggcggctg gctgtcggcc
     4741 tccgagacca ccgcggcgat cgtgctggtg ctgatccaga tcgccaccgc gctgctggtc
     4801 gtgcccctgg tctatgtcac cgccgcgatg ctggtggcga cggtggcctt gccgctgatg
     4861 ctcgagcgcg tcgcgcgcat cgactacacc gacctcgagc agcgtcgcgg cggttccaac
     4921 ctgggcagtg cgtggaactc catcctcgcc ggcgtgctct tcctgatcgc gctggtgctg
     4981 tcgctgccgc tgtggctgat cccgggcgcc ggcctgctga tctcggtcac gctcaccggc
     5041 tggctcaacc agcgcgcctt cggctacgac gcgctcatgt accacgccga caggggagag
     5101 ctgaagcgcc tgcgcgagga ctggcggccg cagatgctgc tgctcggcgg cggcacggcc
     5161 ctgcttgcct acgtgcccgt gatcaacctg gtggcgccgg ccttcgccgg cctcgccttc
     5221 gtccactaca tgctcgagac cctgcgccgg caccgcatcc agtacgggat caccgtgctc
     5281 gacgccgagc cgggcgccga cctgcggaaa ctgaaatgaa cttcggtgcc ctgatcatcg
     5341 gcgacgagat cctctccggc cgtcgcagcg acaaacacct cgccaagctg atcgagctgc
     5401 tcggcgcgcg cgggctcaag ctgtcgtggg cgcgctacgc cggcgacgac ttcgaccgcc
     5461 tcgccgacac cctgcgccag accttcgcca ccggcgacgt ggtgttcagc ttcggcggca
     5521 tcggtgccac gccagacgac cgcacccgcg aggccgcggg cgctgcgctc ggcctggagc
     5581 tcgcgctgca ccccgaggcc gaggccgaga tccgcgcccg cttcggcgcc gagatcaccc
     5641 ccgagcgcct gcagatgggc gtgtatccgg tgggcagcga gatcatcccc aacagcttca
     5701 accgcatccc gggcttctcg atccgccagc actacttcac ccccggcttt ccggtgatgg
     5761 cgtggccgat ggtggagtgg gtgctcgaca cgaaatacgc ccacctgcac cacgccgagg
     5821 actacgtcga gcaggcggtg acggtgtggg atgcctacga gggtcagctg atcggcctga
     5881 tgcgccaggt caccgccgac ttccccgaca ccacgctgtt cagcctgccc acgatcgcgg
     5941 ccgagggcca gcggcgttcg ctcgagctcg gcatgaaggg tacggcggcg cgcgtcgcgg
     6001 cggcgatggc ggtgatcaag gcagacctct ccgcacgcgg gctggagtgg gaagacaagg
     6061 cttgagcgct cgggcggcgg cctcggaaga gccgcacagc ctgctcgtcg agggtacccg
     6121 ggtcgatctg gtgctgcgcc gctcggcgcg acgctcgttc acgctccagg tggaccatcg
     6181 cggcgcgcgc gtgtcggtgc cgctgcgcac gccgctcggc gaagtcgagc gcttcgtgca
     6241 cagccatggg tcctggctgc tcgaccgcct gcgcgcgcgg gcgcaggcgc cgcagccgcc
     6301 gcggctggag gtggccgagg gcgtgcgcct gccgctcttc gggcgtgcac tggtgctgcg
     6361 cctcgtgtcg gcgcgagcgg cgcgctggcg ggcggcggac ggtggcgagg aactcctgtt
     6421 gcccgcgggc gtcgatccgc agcgggcgct ggtgcgtgcg ctgcgtgcgc gggcgctggc
     6481 ctggtaccgc ggacgggtgg aggagttctg ccatcgcctc ggtgtcccgg tctccgccgt
     6541 gagtctttcg agcgcggcca cgcgctgggg cagctgcagc acccgctccg gcatccgcct
     6601 gcactggcgg ctgatccacc tcgagccggc gctgatcgac tacgtggtcg cccacgaggt
     6661 cgcgcacctg gccgagatga accactcgcc acgtttctgg gcggtggtcg agcgcctgta
     6721 cccggactgg cgcgccgcgc gtgccgccct gcgccgcgcg gcggcgacgc tgccggtgat
     6781 cgcgaccgcc gcgagcgatc gcggccgctt cgccggcgaa gactgaaccc ctccaacaca
     6841 ggaagaaccc catgcgaatc cttcacacca tgctgcgcgt cggcgatctc gagcgctcgc
     6901 tcgccttcta caccgaggtg ctgggcatgc gcctgctacg ccgccaggac taccccgatg
     6961 gcaagttcac gctcgccttc gtcggctacc aggacgaggc agaggccgcg gtgctggagt
     7021 tgacccacaa ctggggggtg ggcaagtacg agctcggcac cgcctacggc catatcgcgc
     7081 tcgaggttgc ggatgcgaag aaggcttgcg acgacatccg cgcacgtggc ggcaaggtgg
     7141 tgcgggaggc cgggccgatg aagcacggca cgaccgtgat cgccttcgtc gaggatccgg
     7201 acggctacaa ggtcgagctg atcgagcgca agggctgagc ggcgggagcc ggccggcaca
     7261 gccggcggct tgccggcctc agcaggaggg caggacgggc tcggccggct cgtcctggta
     7321 gcgcgactgc actgcgagga cctggtccca ggcgcgaaag agggcgtcta cacgggcagg
     7381 atcgaagtgg ctgccgcggc cttcgcgcag cagcgagatc gcgcgcgaca tcggccaggc
     7441 aggcttgtac ggccgcgacg aggtgagggc gtcgaagacg tcggcgaccg cgacgatgcg
     7501 gccttcgatc ggaatcgatt cgccagcgag cccgtgcggg tagccgctgc cgtcgaactt
     7561 ttcgtggtgg gtcagcgcaa tcgtcgcgcc caggcgcagg atgctggacg aggagccctt
     7621 gaggatgtcg tggccgatct gcgggtggcg cttcatcacc gcgaattctt ccggtgtcag
     7681 gcgaccgggc ttgagcagga tg
//
LOCUS       DAOTIN010000149         7533 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_11721_length_7533_cov_9.934207, whole genome shotgun sequence.
ACCESSION   DAOTIN010000149 DAOTIN010000000
VERSION     DAOTIN010000149.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 7533)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 7533)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7533
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_11721_length_7533_cov_9.934207"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..2028
                     /locus_tag="P5537_15180"
     CDS             <1..2028
                     /locus_tag="P5537_15180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HRV79429.1"
                     /translation="GVQRLYGVGAPDFAPGSGYIAIGAPLERSLDAVGQRLLLHLGLV
                     AAIALVSALLARFYIYRLVEVWAARVRGAIDQIAAGRRDARIGPPTGVVELDALSAGI
                     ERMAVDIGKREAELQRLSMVIEQSPESIVMTDTAGSILYVNAAFQRITGYAREEVLGR
                     NPRILNGGLTPRATYEQMWATLLAGEVWRGEFHNLRKDGSSYLELATIAPIKDAGGVV
                     THYVAVKEDITQRKQSEALLHRLAYFDALTELPNRALLHDRIAQAIRSGARRESFGML
                     MLVDIDRFRQLNDTLGHAAGDRLLREVAARLRANVREEDTVARHGDDDFAVLVERIGE
                     TEADALGHAEHIARKLQHALQQPFVLGGKEGDRHFATLSIGISLFHDGVSSLESLLKQ
                     AEVALYRAKQDGRDVVRFFNPEMQAVVDAHARLEARMREALEANAFRLFFQPQVNRRG
                     VVIGAEALLRWPLDGGAMVSPAEFIPLAEDTGHIVRLGLWVLRSACAQLARWQMNEST
                     RHLKIAVNVSARQFHQPDFVASVKDTVRAAAIDPCRLELELTESAILSDVDETIRRMN
                     ELRALGIRFALDDFGTGYSSLSYLKRLPFDQLKIDQSFVRDMAEDESSEAIVLAILSL
                     SHALGLEVVAEGVEMPEQRDFLRQHGCDAFQGYLFGKPLPMEAWGDFLEMI"
     gene            complement(2048..3355)
                     /gene="guaD"
                     /locus_tag="P5537_15185"
     CDS             complement(2048..3355)
                     /gene="guaD"
                     /locus_tag="P5537_15185"
                     /EC_number="3.5.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008892 - guanine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006147 - guanine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanine deaminase"
                     /protein_id="HRV79430.1"
                     /translation="MTPSAPSSPPLAAVRGEIVHFLADPAADPRALEHFADGVLIVRD
                     GHVAECGPATALLAKLPAGTPLADHRGKLILPGFVDTHVHYPQTDIIASHGEQLLEWL
                     EKYTFPAERRFADPAHAAEVAGFFCDELLRNGTTTAAAFATVHPASVEALFEAAQQRR
                     MRLITGKVLMDRNCPDFLRDTAETGYADSQALIERWHNRDRLLYAITPRFAPTSTPAQ
                     MALAGRLFREHPGVFLQSHLAENRAEVAWVAQLHPEARSYLDVYERAGQLGMRALFAH
                     CLWLDDSDRRRMAERGAAMSFCPTSNLFLGSGLFDLARARALGVRVGLGTDVGGGTSL
                     SMLQTLNEAYKVLQLGGQSLSAASGFYLATLGGAHSLYLDDRIGNFASGKEADFVVLD
                     PRATPLLARRSAACTTLEERLFVLMMLGDDRAVAATYVMGVPM"
     gene            complement(3352..4518)
                     /gene="xdhC"
                     /locus_tag="P5537_15190"
     CDS             complement(3352..4518)
                     /gene="xdhC"
                     /locus_tag="P5537_15190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA];
                     GO_process: GO:0009115 - xanthine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0065003 - protein-containing complex
                     assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase accessory protein XdhC"
                     /protein_id="HRV79431.1"
                     /translation="MRPWISTLSRLLDTASPAVLVTVAASDGSVPRAPGAHMVVTADR
                     THGSVGGGRLEQRAIEIARQLLVADACPPRLERFALGASLGQCCGGVVVLVFEPVGPA
                     QRAWVRDAAALAASGRAWGRRVRIDGPCAGEVAVFDGDSLEHTCGPAHAAHARTLLAA
                     GAETALLLATPCRRAAGREPAAEPASTPGLGTARDTACETTTLLDASPPPALQVVMFG
                     AGHVGRALAELFGRLPLRVRWIDERAGEFPPTVAANIETRCTDTPTAEVRDAPAAAVF
                     LVLTHSHALDFELIEAILARADFRFCGLIGSRTKRARFAHRLHARGIDEARIARVRCP
                     VGLPGLAGKEAEVIALAIAAEVMRLRPQTQPASLPRRRVTVAPAAQPTESGQET"
     gene            complement(4549..6933)
                     /gene="xdhB"
                     /locus_tag="P5537_15195"
     CDS             complement(4549..6933)
                     /gene="xdhB"
                     /locus_tag="P5537_15195"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004327391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004854 - xanthine dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA];
                     GO_process: GO:0009115 - xanthine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase molybdopterin binding
                     subunit"
                     /protein_id="HRV79432.1"
                     /translation="MNEAIERDGLPPPAVRHPHPHESAHLHVAGEATYVDDLPEPAGT
                     AHAALALSTQAHARIVAMDLAAVLAAPGVIGVLVAADIPGRNDCGPVVHDDPILAAEE
                     VHYVGQPVFAVVARDRELARRAARLARIDYAALPARLDPVEAARAGELVLPPMRLLRG
                     DVDAALAAAPHRIEGQWQLGGQEHFYLEGQVALAQPREDGCMQLWCSTQHPSEMQQAV
                     AHCLGIAAHRLVVEMRRMGGGFGGKESQSALFACVAALAAAKFRRPVKLRPDRDDDIM
                     ITGKRHDFHHDYAAAYDDEGRILALRVDMIARAGFSADLSGPVATRAICHVDNAYHLP
                     AADIRALLARTHTQSNTAFRGFGGPQGAILAEWVIDGIARTLGRDPLDVRRANFYGGP
                     GRDTTPYGQVVADNVLHELVDELEASSDYRARRNAVAAFNAASPVLRRGLALTPVKFG
                     ISFNLTHFNQAGALVHVYTDGSVLVNHGGTEMGQGLHTKVCQVVAAELGIALERVRAT
                     ATDTSKVANTSATAASTGADLNGQAAAAAARTIRTRLAAFATRRFGEDGHGEDTGAAR
                     AHGPAADPAAVHFADGRVRVGTRTIPFAELVAEAYRARVQLWSDGFYATPGLHWDAAT
                     LTGHPFHYFAYGAAVSEVVVDTLTGEWRLLRADLLHDAGSSLNPAIDRGQVEGAFIQG
                     MGWLTTEELWRNAEGRLMTHAPSTYKIPAAHDCPPELRVRLFHNPRRADTILHSKAVG
                     EPPLLLGFSVFFALRDAIAAAGDGRTNPPLRAPATPEAILDAIDAVRRPPTSDA"
     gene            complement(6944..>7533)
                     /locus_tag="P5537_15200"
     CDS             complement(6944..>7533)
                     /locus_tag="P5537_15200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HRV79433.1"
                     /translation="GGNVANGSPIGDSMPALIALGARVVLASVRGRRSLALEDFYLDY
                     LKKDLAADEIVEAIELPAPAPAQRVRSWKLAKRFDSDISAVCAGFALELRAGAIHAPR
                     IAIGGMAATPRRATATEAALAGRPWDEATLAAAQRALADDFAPLDDLRASAGYRSRAA
                     AGLLTRFFLETRPDAPLAAAQTRAFAAEDLAGGGG"
BASE COUNT         1009 a         2575 c         2922 g         1027 t
ORIGIN      
        1 ggcgtgcagc gcctgtatgg cgtcggcgcg ccggactttg ccccgggcag cgggtacatc
       61 gccatcggcg cgccactgga gcgctcgctg gacgcggtgg ggcagcgcct gctgctgcac
      121 ctgggcctgg tcgcggccat cgcgctcgtc tccgcgctgc tcgcgcgctt ttacatctac
      181 cgcctggtcg aggtgtgggc ggcgcgcgtg cgcggcgcga tcgatcagat cgccgccggc
      241 cggcgcgacg cgcgcatcgg accgcctacc ggcgtggtcg agctcgacgc gctctccgcc
      301 ggcatcgagc gcatggcggt ggacatcggc aagcgcgagg cggagctgca gcgcctgtcg
      361 atggtgatcg agcagagccc cgagtcgatc gtcatgaccg acaccgccgg cagcatcctc
      421 tatgtcaacg cggccttcca gcgcatcacg ggctatgcgc gcgaagaggt gctcggacgc
      481 aacccgcgca tcctcaacgg cggcctgacc ccgcgcgcga cctacgagca gatgtgggcc
      541 acgctgctgg ccggggaggt ctggcgcggc gagttccaca acctgcgcaa ggacggttcg
      601 agctatctcg agctggccac gatcgcgccg atcaaggacg cgggtggcgt ggtcacgcac
      661 tacgtcgccg tcaaggaaga catcacccag cgcaagcagt ccgaggccct gctgcaccgg
      721 ctcgcctact tcgatgcgct caccgagctg cccaaccgcg cgctgctgca cgaccgcatc
      781 gcccaggcca tccgcagcgg cgcccgccgc gagagcttcg gcatgctgat gctggtcgac
      841 atcgatcgct tccgccagct caacgacacc ctcggccacg ctgcgggcga ccgtctgctg
      901 cgcgaggtgg ccgcgcgcct gcgcgcgaac gtgcgcgagg aggacacggt cgcgcgccac
      961 ggcgacgacg acttcgccgt gctcgtcgag cgcatcggcg agaccgaggc cgacgcgctc
     1021 ggccatgccg agcacatcgc gcgcaagctc cagcatgcat tgcagcagcc ctttgtgctc
     1081 ggtggcaagg agggcgaccg ccacttcgcg accctgagca tcggcatcag cctgttccat
     1141 gacggggtga gctcgctcga gagcctgctc aagcaggccg aggtggcgct ctaccgcgcc
     1201 aagcaggacg gacgcgacgt cgtgcgcttc ttcaaccccg agatgcaggc ggtggtcgac
     1261 gcccacgccc gcctggaggc ccgcatgcgc gaggcgctgg aggcgaacgc cttccggctc
     1321 ttcttccagc cccaggtgaa ccggcgcggc gtggtgatcg gcgccgaggc gctgctgcgc
     1381 tggccgctcg atggcggcgc catggtgtcg ccggccgagt tcatcccgct cgccgaggac
     1441 accggccaca tcgtccgcct cggcctgtgg gtgttgcgca gcgcctgcgc ccagctcgcg
     1501 cgctggcaga tgaacgagag cacgcgccac ctcaagatcg cggtcaacgt gagcgcgcgc
     1561 cagttccacc agcccgactt cgtcgccagc gtgaaggaca ccgtgcgcgc cgcggccatc
     1621 gacccctgcc gcctcgagct cgagctcacc gagagcgcga tcctgtcgga cgtggacgag
     1681 accatccggc gcatgaacga gctgcgcgcg ctcggcatcc gcttcgcgct cgacgacttc
     1741 ggcaccggct actcctcgct gtcctacctc aagcgcctgc ccttcgacca gctcaagatc
     1801 gaccagtcct tcgtgcgcga catggccgag gacgagagca gcgaggcgat cgtgctggcg
     1861 atcctgtcgc tgagccacgc gctcggcctg gaggtggtgg ccgaaggcgt cgagatgccg
     1921 gagcagcgcg acttcctgcg ccagcacggc tgcgacgcct tccagggcta cctgttcggc
     1981 aagccgctgc cgatggaagc ctggggcgac ttcctcgaga tgatctgagg ccggccgcgc
     2041 ggctggtcta catcggcacg cccatcacgt aggtggccgc caccgcacgg tcgtcgccca
     2101 gcatcatcag cacgaagagg cgctcctcca gcgtcgtgca tgcggcgctg cggcgggcga
     2161 gcagcggggt ggcgcgtggg tcgaggacga cgaagtcggc ctccttgccg gacgcgaagt
     2221 tgccgatgcg gtcgtcgagg tagaggctgt gcgcgccgcc cagggtggcg aggtaaaaac
     2281 cgctcgccgc cgacagcgac tggccgccga gctgcagcac cttgtaggcc tcgttgaggg
     2341 tctgcagcat cgacaggctg gtgccgccgc ccacgtccgt gcccaggccc acgcgcacgc
     2401 cgagcgcgcg cgcgcgcgcc aggtcgaaga ggccggagcc gaggaagagg ttggaggtgg
     2461 ggcagaagct catcgccgcg ccgcgctcgg ccatgcgccg gcggtcgctg tcgtcgagcc
     2521 agaggcagtg cgcgaacagc gcacgcatgc cgagctggcc ggcgcgctcg tagacgtcga
     2581 gatagctgcg cgcctcgggg tggagctgcg caacccaggc cacctcggcg cggttctcgg
     2641 ccaggtgcga ctgcaggaag acccccgggt gctcgcggaa cagacgcccg gcgagcgcca
     2701 tctgcgcggg cgtggaggtg ggcgcgaagc gcggcgtgat ggcgtagagc aggcggtcgc
     2761 gattgtgcca gcgctcgatc agcgcctgcg agtcggcgta tccggtctcg gccgtgtcgc
     2821 gcaggaagtc ggggcagttg cggtccatca gcaccttgcc ggtgatcagg cgcatgcggc
     2881 gctgctgcgc ggcctcgaaa agcgcctcca ccgaggccgg gtgcaccgtg gcgaaggcgg
     2941 ccgcggtggt ggtgccgttt ctcagcagct cgtcgcagaa gaagccggcc acctcggcgg
     3001 cgtgcgcggg atcggcgaag cggcgctcgg cggggaaggt gtatttctcc agccattcga
     3061 gcagctgctc gccatggctg gcgatgatgt cggtctgcgg gtaatgcacg tgggtgtcga
     3121 cgaagccggg caggatgagc ttgccgcggt ggtctgcgag cggcgtgccg gccggcagct
     3181 tcgccagcag cgcggttgcg gggccgcatt cggcgacgtg gccgtcgcgc acgatcagca
     3241 cgccgtcggc gaagtgctcg agcgcgcgag ggtcggcggc ggggtcggcg aggaagtgca
     3301 cgatctcgcc gcgcacggcg gcgagcggcg gggagctggg ggcggagggc gtcatgtctc
     3361 ttggccggat tccgtgggtt gcgctgccgg tgcgaccgtt acgcgccggc gcggcaggct
     3421 cgcgggctgc gtctgcgggc gcaggcgcat cacctcggcg gcgatcgcga gcgcgatcac
     3481 ctcggcttcc ttgccggcca gcccgggcag gccgaccggg cagcgcacgc gggcgatgcg
     3541 ggcttcgtcg attccgcgcg cgtgcaggcg gtgggcgaag cgtgcgcgct tggtgcgcga
     3601 gccgatcagg ccgcagaagc ggaagtcggc gcgcgcgagg atggcctcga tcagctcgaa
     3661 atcgagcgcg tggctgtggg tgagcacgag gaacaccgcc gctgcggggg cgtcgcgcac
     3721 ctccgccgtc ggcgtgtcgg tgcagcgcgt ttcgatgttg gccgcgaccg tgggtggaaa
     3781 ctcgcccgca cgctcgtcga tccagcgcac ccgcagcggg agcctgccga acagctccgc
     3841 cagcgcgcgc ccgacgtgcc cggcgccgaa catcacgacc tgcagcgccg gtggcgggct
     3901 cgcgtcgagc agggtcgtcg tctcgcacgc cgtgtcgcgt gcggtgccga ggcccggcgt
     3961 gctcgccggc tccgccgcgg gttcgcggcc ggcggcacgc ctgcaggggg tggcgaggag
     4021 gagggcggtt tcggcgccgg cggcgaggag cgtgcgtgcg tgggcggcat gggccggccc
     4081 gcacgtgtgc tccagcgaat cgccgtcgaa gaccgcgacc tcgccggcgc agggaccgtc
     4141 gatgcgcacc cgccgtcccc aggcgcggcc gctggcggcc agcgcggcgg cgtcccgcac
     4201 ccacgcccgc tgtgccgggc cgaccggttc gaagacgagc accacgacgc cgccacagca
     4261 ctggccgagg ctggcgccga gggcgaagcg ttcgaggcgc gggggacagg cgtcggccac
     4321 gagcagctgg cgcgcgatct cgatggcgcg ctgctccagc cggccaccgc cgacgctgcc
     4381 atgcgtccga tcggccgtca ccaccatgtg cgcccccggc gccctcggta ccgagccatc
     4441 gctggcggcg accgtgacca ggaccgcagg gcttgcggtg tcgagcagac gcgagagggt
     4501 ggagatccag gggcgcaagg gggagtgtga ggcgtcgggg gtgggctgtc aggcgtcgga
     4561 agtcggcggc cggcgcacgg cgtcgatcgc gtcgaggatg gcctcgggcg tggcgggtgc
     4621 gcgcaggggt gggttggtcc ggccgtcgcc ggcggcggcg atggcatcgc gcagcgcgaa
     4681 gaagaccgag aagccaagca gcagcggcgg ctcgcccacc gccttggagt gcaggatggt
     4741 gtccgcacgc ctggggttgt ggaacaggcg tacgcgcagc tcgggcgggc agtcgtgcgc
     4801 ggcggggatc ttgtaggtgg agggggcgtg ggtcatcagc cggccttcgg cgttgcgcca
     4861 cagctcctcg gtggtgagcc agcccatgcc ctggatgaag gcgccctcga cctggccgcg
     4921 gtcgatcgcc gggttgagcg agctgccggc gtcgtgcagc aggtcggcgc gcagcaggcg
     4981 ccattcgccg gtgagcgtgt cgaccaccac ctcggacacc gccgccccgt aggcgaagta
     5041 gtggaaggga tgtccggtga gcgtggcagc gtcccagtgc agcccgggcg tggcatagaa
     5101 gccgtcggac cacagctgca cgcgggcgcg gtaggcctcg gcgacgagct cggcgaaggg
     5161 gatcgtgcgc gtgccgacac gcacccggcc gtcggcgaag tgcaccgcgg ccgggtcggc
     5221 ggctggaccg tgcgcgcgtg cggcgccggt gtcctcgccg tggccgtcct cgccgaagcg
     5281 gcgcgtggcg aacgccgcca ggcgcgtgcg gatggtgcgc gccgcggccg ccgcggcctg
     5341 gccgttgagg tccgcgccgg tggaggcggc ggtggccgag gtgttggcga ccttgctcgt
     5401 gtcggtggcg gtggcacgca cgcgctcgag cgcgatgccg agctcggccg cgaccacctg
     5461 gcagaccttg gtgtgcaggc cctggcccat ctcggtgccg ccgtggttca ccagcaccga
     5521 gccgtcggta tacacatgca cgagcgcgcc ggcctggttg aagtgggtga ggttgaagga
     5581 gatgccgaac ttgaccgggg tgagcgccag cccgcgccgc agcaccgggc tggcggcatt
     5641 gaaggcggcg actgcgttgc ggcgggcgcg gtagtcgctg ctcgcctcga gctcgtcgac
     5701 gagctcgtgc agcacgttgt cggcgacgac ctggccgtag ggcgtggtgt cgcgccccgg
     5761 gccgccgtag aagttggcgc ggcgcacgtc gagcgggtcg cgcccgagcg tgcgcgcgat
     5821 gccgtcgatc acccactcgg caaggatcgc gccctgcggt ccgccgaagc cgcggaaggc
     5881 ggtgttcgac tgcgtgtggg tgcgtgcgag gagggcgcgg atgtccgcgg ccggcaggtg
     5941 gtaggcgttg tcgacatggc agatcgcgcg cgtggcgacc gggccgctga ggtcggcgga
     6001 aaaacccgcg cgcgcgatca tgtcgacacg cagcgcgagg atgcggccct cgtcgtcgta
     6061 ggccgcggcg tagtcgtggt ggaagtcgtg gcgcttgccg gtgatcatga tgtcgtcgtc
     6121 gcggtcgggg cgcagcttga ccgggcggcg gaacttcgcc gccgccagcg ccgccacgca
     6181 ggcgaacagc gccgactgcg attccttgcc gccgaagccg ccgcccatgc ggcgcatttc
     6241 caccaccaag cggtgggcgg cgatacccag gcagtgcgcc accgcctgct gcatctcgct
     6301 cggatgctgg gtggagcacc acagctgcat gcagccgtcc tcgcgcggct gggcgagcgc
     6361 gacctggcct tcgaggtaga agtgctcctg gccgccgagc tgccattgcc cctcgatgcg
     6421 gtgcggcgcc gccgccagcg ccgcgtccac gtcgccgcgc agcaggcgca tcggcggcag
     6481 cacgagctcg cccgcgcgcg cggcctcgac cgggtcgagc cgcgccggca gcgctgcgta
     6541 gtcgatgcgg gcgaggcggg cggcgcggcg ggcgagttcg cggtcgcggg cgacgacggc
     6601 gaacaccggc tggccgacgt agtgcacttc ttctgccgcg aggatggggt cgtcgtgcac
     6661 caccggcccg cagtcgttgc gccccgggat gtcggcggcg accagcaccc cgatcacgcc
     6721 gggggcggcg agcaccgcgg cgaggtccat cgccacgatg cgggcgtggg cctgcgtcga
     6781 cagggcgagc gccgcatgcg cggtaccggc gggttcgggg aggtcgtcga cgtaggtggc
     6841 ctcgccggcc acgtgcaggt gcgcggactc gtgcgggtgc gggtggcgca ccgcgggggg
     6901 cgggaggccg tcacgctcga tcgcttcgtt catcgcgtcc tcctcagcct ccgccgccgg
     6961 cgagatcctc cgcggcgaag gcgcgcgtct gcgcggcggc gagcggcgca tcggggcggg
     7021 tctcgaggaa gaagcgtgtg agcaggccgg cggcggcgcg gctgcggtag ccggcgctcg
     7081 cgcgcaggtc gtcgagcggg gcgaagtcgt ccgcgagcgc gcgctgcgca gcggcgagcg
     7141 tggcctcgtc ccagggccgg ccggcgagtg cggcctcggt ggcggtggcg cgccggggcg
     7201 tcgccgccat gccgccgatg gcgatgcgcg gggcgtggat cgctcccgcg cgcagctcga
     7261 gcgcgaagcc ggcgcacacc gcggagatgt cggagtcgaa gcgcttggcc agcttccagc
     7321 tgcgcacgcg ctgcgcgggc gcgggggcag gcagctcgat ggcctcgacg atctcgtcgg
     7381 cggcgaggtc cttcttcagg tagtcgaggt agaagtcctc cagcgccagg ctgcgccggc
     7441 cgcgcacgct ggcaagcacg acgcgcgcgc cgagcgcgat cagcgccggc atcgagtcgc
     7501 cgatcggcga gccgttggcg acgttgccgc cga
//
LOCUS       DAOTIN010000150         7518 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_11755_length_7518_cov_8.883961, whole genome shotgun sequence.
ACCESSION   DAOTIN010000150 DAOTIN010000000
VERSION     DAOTIN010000150.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 7518)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 7518)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7518
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_11755_length_7518_cov_8.883961"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            18..1256
                     /locus_tag="P5537_15205"
     CDS             18..1256
                     /locus_tag="P5537_15205"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase"
                     /protein_id="HRV79434.1"
                     /translation="MSSLASPPEKVRKGDRRRQRGDRTGFTTGATAAAAATAATLGLV
                     RGAVPGRVECELPNGMRVDFAILDGRVGRINGSECAQAVAIKDGGDDPDATHGAHITV
                     EVRRISNGGGAVVLEGGPGVGIVTRPGLGLEVGGPAINPVPRRNIAANVAAAGAAILQ
                     AGDSLAVRISVPGGEEMAKKTLNARLGILGGISILGTTGIVRPFSTAAWRASVVQAIE
                     VAAAQGRTTLVLTTGGRTEKCAMRSFPQLDEACFVQFGDFVKAAFTTAIRHDIRHIVL
                     GAMVGKLTKIAQGLSVTHAWREEVDRALIAEAAQAVGAPRALVAEIRAAETARFAAER
                     LAELGLAVAFHRALAERALRSLRTRYPGPHRLTVLACNFEGEPIVTVEDDGAPSPATS
                     LFPPCSAPDTAPGPARGETC"
     gene            1269..2675
                     /gene="cbiE"
                     /locus_tag="P5537_15210"
     CDS             1269..2675
                     /gene="cbiE"
                     /locus_tag="P5537_15210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046025 - precorrin-6Y
                     C5,15-methyltransferase (decarboxylating) activity
                     [Evidence IEA];
                     GO_process: GO:0046140 - corrin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6y C5,15-methyltransferase
                     (decarboxylating) subunit CbiE"
                     /protein_id="HRV79435.1"
                     /translation="MSAPSHSSPPSGAHCSVVGLLDDGWSGLSAAARARIASAGCVIG
                     AARTLERVAEHLDPQSTCHTMDGAFFRLPGWIEAARGAGAHSVVLATGDPLCNGIAAS
                     LIDKLGAHAVEVLPAPSTLQLACARLRLPWQDARIASCHGADAGEWMTAPPPSDALQP
                     GAPAPSPGPAHGLYRLVRAVAGHALVLAFTSPANSPDRIARALLAAGYGDPGSGEQVR
                     LSVVARLCLDDEAVFPALSLEDAAARSFPEPNVLVIERRPAAEADRHADALPATTPLF
                     GLEDLDYLQRSPENGLITKLEVRAVSLARLALRADSLVWDIGAGAGSVGLEASRIAHR
                     GHVWAIEKNPADAANARRNARRLRASNYSLLEGKAPAGLDAWPDPDAVFIGGSGGELA
                     ELIVLALQRLKPGGRLVMNFVTVENLATATATLDAAAAAWELTLLSAARSQPILDMHR
                     LAAQNPVWILTARKETSR"
     gene            2672..3529
                     /gene="cobI"
                     /locus_tag="P5537_15215"
     CDS             2672..3529
                     /gene="cobI"
                     /locus_tag="P5537_15215"
                     /EC_number="2.1.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030788 - precorrin-2
                     C20-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-2 C(20)-methyltransferase"
                     /protein_id="HRV79436.1"
                     /translation="MNATPPTPRFGRLIGVSLGPGDPELITRRGWAALQSGARWAYPV
                     KKAAERSYALDIARRGGLDIPQDAVELVFPMTRDAEALARAWARAAAQTVQLLAEGRD
                     LVFLVEGDASTYSTFRHLARAARELAAEIEVETIAGVSSFAAAAALADVALAEEDETV
                     AVIPAAYGTALIEHLLDEFDTLVLMKVKPLLDEVIEMLERRGLLATSCFIEKAGAPGE
                     RVVRDVASLRGETVNYLSLLLVSNPKRARGELRRGCRRRAEHAAARSIPPAHTMEAAL
                     ANSVEGLAP"
     gene            3601..4365
                     /locus_tag="P5537_15220"
     CDS             3601..4365
                     /locus_tag="P5537_15220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018987717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis central domain-containing
                     protein"
                     /protein_id="HRV79437.1"
                     /translation="MLPFPPGRLAVVAITRHGIALAGRVVAALPGARLFAPRKYHSEA
                     HAAAPGACACYEGKVGAQVPALFANFDGLVAIVSLGAVVRLIAPHLKDKDSDPGVVVL
                     DEAARWAIPVLSGHLGGANAIAAALQTAIGATAVLTTASDARGTLAVDLLGRELGWSL
                     EASHDELVRASAAMVNDEAVALVQEAGRRDWWPGHANGRSGPLPANLHCFDRLEEVEP
                     ECFGAVLWIAHRTLPAAYEARLAGKRVIYRPGVEQA"
     gene            4362..4883
                     /locus_tag="P5537_15225"
     CDS             4362..4883
                     /locus_tag="P5537_15225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HRV79438.1"
                     /translation="MSPPPSQGGAAPAAPAPSATGPGCGTLGRVASLPVCVALGLGCD
                     RGTPAETIAQAVAEALTQAAIRLGTPALEVTAAASITLKADEAGLLEVAAAAGWALHF
                     YDAERLAGVTVPNPSATVRRYTGTPSVSEAAALLAAGTSLAADPGALLVEKHRLRGAD
                     GRNATVSIARMPR"
     gene            4880..5851
                     /gene="cobJ"
                     /locus_tag="P5537_15230"
     CDS             4880..5851
                     /gene="cobJ"
                     /locus_tag="P5537_15230"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030789 - precorrin-3B
                     C17-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HRV79439.1"
                     /translation="MNPTEPLRPAIPGGRIMLVGLGPGAHEHLTARARAAIAEADTVI
                     GYVTYIRLVAELLEGKEVIRKSMTEELDRAIEALARARQGRKVALISSGDAGVYGMAG
                     PTFEVLFQAGWTPDSGIEVEIVPGASALNTCAALVGAPLTHDFCAISLSDLLTPWPTI
                     ARRLDAVAYADFVVALYNPRSGRRTGQIVEAQRLFLRHRDPATPVAIVKSAYRPKQRI
                     EFTTLERMTEADIGMLTTVLIGNSQTFVRDGLMVTPRGYASKYALDAGERATVDGEQS
                     GRSLSTGLEGWLATIRASGRSATELADTYRLPEAYIRVALAGAEAPV"
     gene            5984..7282
                     /locus_tag="P5537_15235"
     CDS             5984..7282
                     /locus_tag="P5537_15235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase C-terminal
                     domain-containing protein"
                     /protein_id="HRV79440.1"
                     /translation="MSRLQALYDSKRMMPTDAAGLVRDGDTVVVPTGVGEPPALLHAL
                     SARRHELRDVAVSQILPLRKFAYLDPDTRANIRHDAYFFGGASRPGGQAGWVDYVPAY
                     FSELPMLIDRGLLPAEVVVSLASPMDEHGYFSLSLAPDYTMAAIRRARVVLLEVNPNV
                     PFANGDCLVHISQVAGLVESDEELFEVGLPEIGPVQQAIGKHVAELIDDGSTLQIGYG
                     GIPDAVVMQLQHKRDLGIHTEMLGDGILSLIESGAVTNRRKTFMPGRTIATFALGSRR
                     LYRTMHRNPGIEMHPVEFTNDPYLAARNDKLCAINATMQIDLIGQCGSETLGHLPYSG
                     TGGQADFVRAANRSKGGKAFIVLPSTAKNGTVSRIAPVLSPGTHVTTSKNDINYVVTE
                     YGVAQLRGKTAKQRAEALIGIAHPDFRGELREAARKMSLL"
BASE COUNT         1074 a         2969 c         2507 g          968 t
ORIGIN      
        1 gccctcctga cgccccgatg tcttccctgg cttccccccc cgagaaggtc cgcaaaggcg
       61 accgccgtcg ccagcgcggc gaccggaccg gcttcaccac cggcgccacc gcggccgccg
      121 ccgcgaccgc agccacccta ggcctcgtgc gcggcgccgt gcccgggcgg gtggagtgcg
      181 agctgcccaa cggcatgcgg gtcgacttcg ccatcctcga cggtcgcgtc gggcggatca
      241 acggcagcga gtgcgcgcag gcggtagcga tcaaggacgg cggcgacgac cccgacgcca
      301 cccacggcgc ccacatcacg gtggaggtcc gccgcatctc caacggtggc ggcgcagtcg
      361 tgctcgaagg cggccccggc gtcggcatcg tcaccagacc ggggctgggg ctcgaggtgg
      421 gcggccccgc gatcaacccc gtgccgcggc gcaacatcgc cgccaacgtc gccgcggccg
      481 gtgccgccat cctgcaggcc ggcgacagcc tggcggtgag gatctccgtg cccgggggcg
      541 aagagatggc gaagaagacc ctcaacgccc gcctcggcat cctcggcggc atcagcatcc
      601 tcggcaccac cggcatcgtg cgccccttct ccacggcggc ctggcgcgcc agcgtggtgc
      661 aggcgatcga ggtcgccgcg gcgcaggggc ggaccacgct ggtgctgacc accggcgggc
      721 gcaccgagaa atgcgcgatg cgcagcttcc cgcagctcga cgaggcctgc ttcgtgcagt
      781 tcggcgactt cgtcaaggcg gcgttcacca ccgcgatccg ccacgacatc cgccacatcg
      841 tgctcggcgc catggtcggc aagctcacca agatcgccca gggcctgtcg gtgacccatg
      901 cctggcgcga agaggtcgac cgtgcgctga tcgccgaggc cgcgcaggcg gtcggcgccc
      961 cgcgcgcgct cgtcgccgag atccgcgccg ccgagaccgc ccgcttcgcc gccgaacgcc
     1021 tggccgaact cggcctcgcc gtcgccttcc accgcgccct cgccgaacgc gcgctccgca
     1081 gcctgcgtac ccgctacccc gggccacacc gcctcaccgt gctcgcctgc aacttcgagg
     1141 gcgagcccat cgtgacggtc gaggacgatg gcgcaccctc cccagccacc tcgcttttcc
     1201 ccccttgctc cgcaccggac accgcacccg gtccggcccg cggcgaaacc tgctgaagcc
     1261 tgcacacgat gtccgcaccc tcgcattcct ccccgccctc cggcgcgcac tgcagcgtgg
     1321 tcggcctcct cgacgacggc tggagcggcc tctccgccgc ggcacgcgca cgcatcgcca
     1381 gcgcaggctg cgtgatcggt gccgcgcgca cgctggagcg ggtcgccgag cacctcgacc
     1441 cgcagtcgac gtgccatacg atggacggcg ccttcttccg cctccccggc tggatcgagg
     1501 ccgcccgcgg cgccggcgcc cacagcgtcg tgctcgccac cggggacccg ctctgcaacg
     1561 gcatcgccgc aagcctgatc gacaagctcg gcgcgcacgc ggtggaggtg ctgcccgccc
     1621 catccaccct gcagctcgca tgcgcacgcc tgcgcctgcc gtggcaggac gcgcgcatcg
     1681 cctcctgcca cggcgccgat gccggcgagt ggatgaccgc cccgcccccg tccgacgcgc
     1741 tgcagcctgg cgcgccggct ccttcccccg gcccggcaca cggcctctac cgcctcgtgc
     1801 gcgcagtcgc cgggcacgcg ctggtgctcg ccttcaccag cccggccaac agccccgacc
     1861 gcatcgcccg cgccctgctc gccgccggct acggcgaccc aggcagcggc gagcaggtcc
     1921 gcctctcggt ggtcgcacgc ctgtgcctgg acgacgaagc ggtgttcccc gcgctgagcc
     1981 tggaggacgc cgctgcacga agcttccccg agcccaacgt gctggtgatc gagcgccgcc
     2041 cggccgccga ggcggaccgc catgccgacg ccttgcccgc caccaccccg ctgttcggcc
     2101 tcgaagacct cgactatctg cagcgcagcc cggagaacgg cctgatcacc aagctcgagg
     2161 tccgcgcggt ctcgctcgcc cgcctcgcgc tgcgcgccga cagcctggtg tgggacatcg
     2221 gcgccggcgc cggctcggtg ggcctggagg ccagccgcat cgcgcaccgc ggccatgtgt
     2281 gggcgatcga gaagaacccc gccgacgccg ccaacgcccg ccgcaacgcc cgccgcctgc
     2341 gcgcgagcaa ctacagcctg ctcgagggca aggcgccagc cgggctggac gcctggcccg
     2401 acccggatgc ggtcttcatc ggcggctcgg gcggcgagct cgccgaactg atcgtcctcg
     2461 ccctgcagcg cctgaaaccc ggtggccgcc tggtgatgaa cttcgtcacc gtggagaacc
     2521 tcgccaccgc caccgccacg ctggatgccg ccgctgccgc ctgggagctc accctgctgt
     2581 cggccgcgcg cagtcagccc atcctcgaca tgcaccgcct cgccgcgcag aacccggtgt
     2641 ggatcctcac cgcccgcaag gagacttccc gatgaacgcc accccaccca ccccacgctt
     2701 cggccgcctg atcggcgtct cgctgggtcc gggcgacccc gaactgatca cccgccgcgg
     2761 ctgggccgcg ctgcagtcgg gcgcgcgctg ggcctatccg gtcaagaagg cggcggagcg
     2821 ctcctacgcc ctcgacatcg cgcgccgcgg cggactcgac atcccgcagg atgcggtcga
     2881 gctcgtgttc ccgatgacgc gcgacgccga ggcgctggcg cgggcctggg cgcgcgccgc
     2941 cgcgcagacg gtgcagctgc tcgccgaagg ccgcgatctc gtcttcctgg tcgagggcga
     3001 cgcctccacc tactccacct tccgccacct cgcgcgcgcg gcgcgcgagc tcgcggccga
     3061 gatcgaggtg gagaccatcg ccggagtcag ctccttcgcc gccgctgcgg cgctcgccga
     3121 cgtggcgctg gccgaggagg acgagaccgt ggcggtgatc cccgccgcct acggcaccgc
     3181 gctcatcgag cacctgctcg acgagttcga caccctggtg ctgatgaagg tgaagccgct
     3241 gctcgacgag gtgatcgaaa tgctcgagcg ccgcggcctg ctcgccacga gctgcttcat
     3301 cgagaaggcc ggtgccccgg gcgagcgcgt ggtgcgcgat gtcgccagcc tgcgcggcga
     3361 gacggtcaat tacctgtccc tgctgctggt gagcaacccc aagcgcgcgc gcggcgaact
     3421 gcgccggggc tgccgccggc gtgccgaaca cgcggccgcc cggtcgatcc cgcctgcgca
     3481 caccatggaa gctgcgctcg caaacagcgt ggaaggcctc gcaccgtgag cgcgggcgct
     3541 cccccgcagg ccggcacgca ccccgccccg gcagaagccg gcgcgccgtg ccccgaggcc
     3601 ctgctgccct ttccgcccgg gcgcctggcg gtggtcgcga tcacccgcca cggcatcgcg
     3661 ctcgccggcc gcgtcgtcgc cgcgcttccc ggcgcgcgcc tgttcgcacc gcggaaatac
     3721 cacagcgagg cgcacgccgc cgcacccggc gcctgcgcct gctacgaggg caaggtcggc
     3781 gcgcaggtgc ccgcgctgtt cgcgaacttc gacggcctcg tcgccatcgt ctcgctcggc
     3841 gcggtggtgc gcctgatcgc cccccacctg aaggacaagg acagcgatcc cggcgtggtc
     3901 gtgctcgacg aggccgcacg ctgggcgatc ccggtactgt ccggccacct cggcggcgcc
     3961 aacgcgatcg ccgccgcgct gcagacggcg atcggcgcca ctgcagtgct gaccacggcc
     4021 tcggacgcgc gcgggacgct ggcggtggac ctgctcgggc gcgagctcgg ctggagcctc
     4081 gaggccagcc acgacgagct cgtgcgcgcg agcgcggcga tggtgaatga cgaagcggtg
     4141 gcgctggtgc aggaagccgg ccgccgcgat tggtggccgg gccacgccaa cggccgcagc
     4201 gggccgctgc cggcgaacct gcactgcttc gaccgcctgg aagaagtcga gcccgagtgc
     4261 ttcggcgccg tgctgtggat cgcccaccgc acgctgcctg ccgcctacga ggcacgcctg
     4321 gcgggcaagc gcgtgatcta tcgcccaggc gtcgagcaag catgagcccg ccgccatcgc
     4381 aaggcggcgc ggcccctgcc gcgcccgcac cgagcgcaac ggggcccggc tgcggcacgc
     4441 tcggccgcgt cgccagcctc ccggtctgcg tcgcgctcgg cctcggctgc gaccgcggca
     4501 cgccggcgga gacgatcgcg caggcagtgg ccgaggccct gacccaggcg gccatccggc
     4561 tcggcacgcc cgcgctcgag gtcaccgccg cggccagcat caccctcaag gccgacgagg
     4621 cgggcctgct cgaggtggcc gcagcggcgg gctgggcgct gcacttctac gatgcggagc
     4681 gcctggccgg cgtcaccgtc cccaacccat cggcgacggt gcgcagatac accggcacgc
     4741 cctcggtctc cgaggccgcg gcgctgctcg cggccggcac ctcgctcgct gccgaccccg
     4801 gcgcgctgct cgtcgaaaaa caccggctgc gcggcgccga cggccgcaac gccaccgtct
     4861 ccatcgcaag gatgccccga tgaaccccac cgaacccctt cgccccgcca ttcccggcgg
     4921 ccgcatcatg ctcgtcggcc tcggccccgg agcgcacgag cacctcaccg cacgcgcccg
     4981 cgccgcgatc gccgaggccg acaccgtgat cggctacgtc acctacatcc gcctggtcgc
     5041 cgagctgctc gagggcaagg aggtcatccg caagtcgatg accgaggagc tcgaccgcgc
     5101 catcgaggcg cttgcgcgtg ctcgccaggg tcgcaaggtc gcgctgatct cgtcgggcga
     5161 cgccggcgtc tacggcatgg ccggccccac cttcgaggtc ctgttccagg ccgggtggac
     5221 gcccgactcg ggcatcgagg tcgagatcgt gcccggcgcc tcggcgctga acacctgcgc
     5281 cgccctggtc ggtgcgccac tgacgcacga tttctgcgcg atctcgctct ccgacctgct
     5341 cacgccctgg ccgaccatcg cccgccgcct ggacgccgtg gcctacgccg acttcgtggt
     5401 cgccctctac aatcccagga gcgggcggcg caccgggcag atcgtggagg cgcaacgcct
     5461 gttcctgcgg catcgcgacc cggccacgcc ggtggcgatc gtcaagtccg cctaccggcc
     5521 gaagcagcgc atcgagttca ccacgctcga acgcatgacc gaggccgaca tcggcatgct
     5581 gaccacggta ctgatcggca attcgcagac cttcgtgcgc gacggcctga tggtcacccc
     5641 gcgcgggtat gccagcaagt acgcgctcga tgcaggcgag cgcgccaccg tcgacggcga
     5701 acaatccgga cgctcgctat cgaccggcct cgaaggatgg ctggcgacga tccgcgccag
     5761 cgggcgcagc gccaccgaac ttgccgacac ctaccgcctg cccgaggctt acatccgcgt
     5821 cgcgctcgcc ggcgcggaag cgccggtctg accggctgac cggctctccg cgaaccgccg
     5881 cggacaatcc ggcgggcgtg ggtacgacgc ccatacgcat cagtatggaa accgcttata
     5941 atcccatttt tgcaatgcag cagaaccttc ggggagaacg accatgagcc gcctgcaggc
     6001 cctctacgac agcaagcgca tgatgcccac cgacgccgcg ggcctggtcc gcgacggcga
     6061 caccgtggtc gtgcccaccg gcgtgggcga gccgcccgcg ctgctgcacg cgctctccgc
     6121 gcgccgccac gaactgcgcg acgtcgcggt gagccagatc ctgccgctgc gcaagttcgc
     6181 ctacctcgac cccgacacgc gcgccaacat ccgccacgac gcctacttct tcggcggcgc
     6241 atcccgcccg ggcggccagg ccggctgggt ggactacgtg ccggcctatt tctccgagct
     6301 gcccatgctg atcgaccgcg gcctgctgcc ggccgaggtg gtggtgtcgc tggcctcgcc
     6361 gatggacgag cacggctact tcagcctctc gctcgcgccc gactacacca tggcggcgat
     6421 ccggcgcgca cgcgtggtgc tgctcgaggt gaacccgaac gtgcccttcg ccaacggcga
     6481 ctgcctggtg cacatctccc aggtcgccgg cctggtggag agcgacgagg agctgttcga
     6541 ggtcggcctg cccgagatcg gcccggtgca gcaggcgatc ggcaagcacg tcgccgagct
     6601 catcgacgac ggctccaccc tgcagatcgg ctatggcggc atccccgacg cggtggtgat
     6661 gcagctgcag cacaagcgcg acctcggcat ccacaccgag atgctgggcg acggcatcct
     6721 gtcgctgatc gagtcgggcg cggtcaccaa ccgcaggaag accttcatgc cgggccggac
     6781 gatcgccacc ttcgcgctcg gctcgcggcg cctgtaccgc accatgcacc gcaacccggg
     6841 catcgagatg cacccggtgg agttcaccaa cgatccctac ctcgctgcgc gcaacgacaa
     6901 gctgtgcgcg atcaacgcca ccatgcagat cgacctgatc ggccagtgcg gctcggagac
     6961 cctgggccac ctgccctact cgggcaccgg cggccaggcg gatttcgtac gcgccgccaa
     7021 ccgctcgaag ggcggcaagg ccttcatcgt gctgccgtcg acggcgaaga acggaacggt
     7081 gtcacggatc gcacccgtgc tgtcgccggg cacccacgtc accaccagca agaacgacat
     7141 caactacgtg gtgaccgagt acggcgtcgc gcagctgcgc ggcaagaccg ccaaacagcg
     7201 cgccgaggca ctgatcggca tcgcgcaccc ggacttccgc ggcgaactgc gcgaggccgc
     7261 gcggaagatg agcctgctct gagggggcgg ctgccggacg gcttgggaga cgctccggca
     7321 agcgaggtgc gtgggcggac ctcgaccgcc gcattcgcgc ctgccggcgc tcctacatga
     7381 accgccgcgc acccgcccct gtaggagcgg cggcagccgc gaacacggcg gtgcggcggc
     7441 gatgggcgtt gtcgtgcgcg gaagcgccgc attcgcgcct gccggcgctc ctacatgaac
     7501 cgccgcgcgc ccgccccc
//
LOCUS       DAOTIN010000151         7322 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_12152_length_7322_cov_9.702766, whole genome shotgun sequence.
ACCESSION   DAOTIN010000151 DAOTIN010000000
VERSION     DAOTIN010000151.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 7322)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 7322)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7322
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_12152_length_7322_cov_9.702766"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..851
                     /locus_tag="P5537_15240"
     CDS             <1..851
                     /locus_tag="P5537_15240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transporter substrate-binding protein"
                     /protein_id="HRV79441.1"
                     /translation="LEKNVFYTGAAPNQQAIPAVEYLMSEEGGGAKRFVLLGTDYVYP
                     RTTNKILRAFLKSKGVSDADILEDYTPFGHADYQTIIARIKQFAAEGKKTAVVSTING
                     DSNVPFYKELGNAGLKATDVPVVAFSVGEEELRGVDTKPLLGHLAAWNYFMSVDNPQN
                     KAFIDKYRAWAKKNAVPNADTVVTNDPMEATYVGLHMWKQAVEKAGSTDVDKVIAAMG
                     GQTFKAPSGFTLTMDATNHHLHKPVLIGEVRADGQFDVVWQTQQPIRAQPWSPFIEGN
                     EGKQGL"
     gene            906..2537
                     /gene="urtB"
                     /locus_tag="P5537_15245"
     CDS             906..2537
                     /gene="urtB"
                     /locus_tag="P5537_15245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0033221 - ATPase-coupled urea
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015840 - urea transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="urea ABC transporter permease subunit UrtB"
                     /protein_id="HRV79442.1"
                     /translation="MFGPTKRQWCIAAALCVLMGLAALPARAALDPALVQGLGGDFNA
                     RVAAIDALGVAGGDEATALLDALEGGRLGTVDGRLVVIAPDGLRDAASGEALAADAGA
                     ATRITVNNRLRRAIGTARAALALSSAQPAQRLAAADTLRENASPALLPVLARALAAES
                     DAAVREVLLYATAKLELSSPDPALRLKAAQALGASSDAAVKNLLAALLEKRGEGAAAT
                     WVEPDAEVRAAAAASMRAIDRRIGLAQTAGTLFSGLSLGSILLLAALGLAITYGVMGV
                     INMAHGELLMVGAYATFVVQGVFRSHFPAYLDLYVLAAIPAAFLAAALVGIVMERLVL
                     RHLYGRPLESLLATWGLSLVLIQAARVLFGPQNLELANPSWMSGGVELAGGVVLPYNR
                     IVILGFAAFVLVLIWLMMQKTRLGMFVRAVTQNRPMAGCVGVPTARVDTLAFAIGSGV
                     AGLGGLALSQIANVGPAMGTGYIVDAFMVVVLGGVGQLAGAVWAALGLGIVAKFLEGW
                     AGAVVAKILVLVFIIAFIQKRPQGIFALKGRFADS"
     gene            2548..3795
                     /gene="urtC"
                     /locus_tag="P5537_15250"
     CDS             2548..3795
                     /gene="urtC"
                     /locus_tag="P5537_15250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0033221 - ATPase-coupled urea
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015840 - urea transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="urea ABC transporter permease subunit UrtC"
                     /protein_id="HRV79443.1"
                     /translation="MRTPFTLRLFQSMPRGGWIALAIFAVVAWIGVPVAHLALPESHP
                     LHVSAYTVSLLGKILCYMVVAVAMDLIWGYAGILSLGHGLFFALGGYAFGMYLMRQIG
                     RDGSYGADIPDFMVFLDWKELPWYWAGSDSLLWALFLVVALPGLVAFVFGWFAFRSRI
                     KGVYFSIITQALTYAAMLLFFRNETGFGGNNGFTDFKRILGYDITSPGMRVTLFALSA
                     ALLIACLVLGRYLVTSRFGRVLAAIRDAESRVMFIGYNPLHYKLFMWTLSAMLCGLAG
                     ALYVPQVGIINPSEMSPANSIEIAVWVAVGGRGTLVGAVLGAGIVNLAKSVFTVYLPE
                     YWPFVLGFLFIVVTLYLPDGVVGLWRKLRARRAAAALDDASAAAGAGRAAAIGGTPAE
                     APVTERQAARSATDTPIAKGANA"
     gene            3792..4658
                     /gene="urtD"
                     /locus_tag="P5537_15255"
     CDS             3792..4658
                     /gene="urtD"
                     /locus_tag="P5537_15255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0033221 - ATPase-coupled urea
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015840 - urea transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="urea ABC transporter ATP-binding protein UrtD"
                     /protein_id="HRV79444.1"
                     /translation="MIPTLEIERESARLDAERENQREHWDGSAADGRVYRPGELDLSH
                     KVILYLDDITVSFDGFRALNKLSLTIDAGELRCIIGPNGAGKTTMMDVITGKTRPDSG
                     TAFFGQTIDLTRLTEPEIAHAGIGRKFQKPTIFEHHSAFENLELAMKADKRVRRTLFA
                     SLLDDERDRVAEVLRQIRLDQAADRPAGLLSHGQKQWLEIGMLLMQEPRLLLLDEPVA
                     GMTDDETERTAELFVSLAGKHSLVVVEHDMAFVEALGGKVTVLCEGSVLAEGDLATVQ
                     ADPRVIEVYLGR"
     gene            4665..5357
                     /gene="urtE"
                     /locus_tag="P5537_15260"
     CDS             4665..5357
                     /gene="urtE"
                     /locus_tag="P5537_15260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015438168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0033221 - ATPase-coupled urea
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015840 - urea transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="urea ABC transporter ATP-binding subunit UrtE"
                     /protein_id="HRV79445.1"
                     /translation="MLKVDTLNQYYGGSHILRGLSFDVPVGQVTTLLGRNGVGKTTLL
                     KTLMGLVPAASGSISFDGRDITRAPSYKRVAAGIGFVPQGREIFPRLTVEENLLMGLA
                     TRPRGSEIPPRIFDMFPVLRQMMGRRGGDLSGGQQQQLAIGRALAFGPKLLILDEPTE
                     GIQPSIIKDIERAIRSLAETGEMAILLVEQYYDFARALADQYLVMERGEIVMRGAGAD
                     MDRDGVREALAV"
     gene            5566..6444
                     /locus_tag="P5537_15265"
     CDS             5566..6444
                     /locus_tag="P5537_15265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA];
                     GO_process: GO:0006807 - nitrogen compound metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="urease accessory protein UreD"
                     /protein_id="HRV79446.1"
                     /translation="MFLHPPPLAASLLAPAGATAPTPWRAGLRLEYERRGARSVLARR
                     EHFGPLRVQRALYPEGEGVCHTLLVHPPAGIVGGDELRVDLRVGTDAHVLLTTPGAGK
                     WYRSAGARGVLEQHIAVAPGAVCEWLPQESIVHEGAVAGLSTEVRLEGDACFIGSEML
                     CFGRTASGERFAHGELAMRTRIERDGRPIWLERGVVHGGGGLLAAAPGLQGQPVSASL
                     LVASPRCDEALRDAWRALAPTAGEGAVSLLPGVLVARWLGPACEPGRQWFARLWAAAR
                     PAVAGRAAHTPRIWNT"
     gene            6484..6786
                     /gene="ureA"
                     /locus_tag="P5537_15270"
     CDS             6484..6786
                     /gene="ureA"
                     /locus_tag="P5537_15270"
                     /EC_number="3.5.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006811999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009039 - urease activity [Evidence IEA];
                     GO_process: GO:0019627 - urea metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="urease subunit gamma"
                     /protein_id="HRV79447.1"
                     /translation="MELSPREKDKLLVFTAGLLAERRRARGLLLNYPEAVALITCAIL
                     EGARDGRSVAELMSFGATLLTRADVMEGVAEMIPDIQVEATFPDGTKLVTVHNPIV"
     gene            6798..7151
                     /locus_tag="P5537_15275"
     CDS             6798..7151
                     /locus_tag="P5537_15275"
                     /EC_number="3.5.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0035550 - urease complex [Evidence IEA];
                     GO_process: GO:0043419 - urea catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="urease subunit beta"
                     /protein_id="HRV79448.1"
                     /translation="MIPGELLVADGDIELAVGRATRTLVVSNTGDRPIQVGSHYHFAE
                     TNTALDFDRAAAHGFRLNIAAGTAVRFEPGQWRTVELVALAGEREVYGFNGLVMGRLD
                     EPARAPAAHRGEGDL"
     gene            7151..>7322
                     /gene="ureC"
                     /locus_tag="P5537_15280"
     CDS             7151..>7322
                     /gene="ureC"
                     /locus_tag="P5537_15280"
                     /EC_number="3.5.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324673.1"
                     /note="ureases catalyze the hydrolysis of urea into
                     ammonia and carbon dioxide; in Helicobacter pylori the
                     ammonia released plays a key role in bacterial survival by
                     neutralizing acids when colonizing the gastric mucosa; the
                     holoenzyme is composed of 3 ureC (alpha) and 3 ureAB
                     (gamma/beta) subunits; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urease subunit alpha"
                     /protein_id="HRV79449.1"
                     /translation="MAKISRRAYAEMFGPTVGDRLRLADTALVVEVEHDFTIYGEEVK
                     FGGGKVIRDGMGQ"
BASE COUNT         1044 a         2642 c         2569 g         1067 t
ORIGIN      
        1 agctggagaa gaacgtcttc tacaccggcg ccgcgcccaa ccagcaggcg atccccgcgg
       61 tcgagtacct gatgagcgag gaaggcggcg gcgccaagcg cttcgtgctg ctcggcaccg
      121 actacgtgta tccgcgcacg accaacaaga tcctgcgcgc cttcctgaag agcaaggggg
      181 tcagcgatgc ggacatcctg gaggactaca cccccttcgg ccacgccgat taccagacca
      241 tcatcgcgcg catcaagcag ttcgccgccg agggcaagaa gacggccgtg gtgtcgacca
      301 tcaacggcga ctccaacgtg cccttctaca aggaactggg caatgccgga ctgaaggcga
      361 ccgacgtgcc ggtggtggcc ttctcggtcg gcgaggagga actgcgcggc gtcgatacca
      421 agcccctgct cggccatctg gcggcgtgga actacttcat gtcggtcgac aacccgcaga
      481 acaaggcctt catcgacaag taccgcgcgt gggcgaagaa gaacgccgtg ccgaacgccg
      541 acaccgtggt caccaacgac ccgatggagg ccacctacgt cggcctgcac atgtggaagc
      601 aggcggtcga gaaggccggc agcaccgacg tcgacaaggt catcgcggcg atgggcgggc
      661 agaccttcaa ggccccgtcg ggcttcacgc tgaccatgga cgcgaccaac caccacctgc
      721 acaagccggt gctgatcggc gaggtgcgcg cggacgggca gttcgacgtc gtctggcaga
      781 cccagcagcc gatccgcgcc cagccgtgga gcccgttcat cgagggcaac gagggcaagc
      841 aggggctgtg atcgtccgga aaatcggggt ctgaccccga ttttcgtctg aagagggagc
      901 cgacgatgtt cggaccgaca aaacgacaat ggtgtatcgc cgccgcgctg tgcgtgctga
      961 tggggctcgc cgcgctgcca gcgcgggcgg cgctcgaccc cgcgctggtg caggggctgg
     1021 gcggtgactt caacgcccgc gtcgccgcga tcgacgcgct cggcgtggcc ggcggcgacg
     1081 aagccacggc gctgctggac gcgctcgagg gcgggcggct cggcacggtg gacggccgcc
     1141 tggtggtgat cgcgcctgac gggctgcgcg acgccgccag cggcgaggcg ctcgccgccg
     1201 acgcgggcgc cgccacccgg atcaccgtga acaaccgcct gcgccgcgcg atcggcaccg
     1261 cacgcgcagc gctcgcgctg tcctccgcgc agccggcaca gcgcctggcc gcggccgaca
     1321 ccctgcgcga gaacgccagc ccggcgctgc tgccggtgct ggcgcgcgcg ctcgctgccg
     1381 aatcggacgc cgcggtgcgc gaggtcctgc tctacgccac cgccaagctc gagctctcct
     1441 cgcccgaccc cgccctgcgc ctgaaggcgg cgcaggcgct cggtgcctcg tccgacgcgg
     1501 cggtcaagaa cctgctcgcc gcgctgctgg agaagcgcgg cgagggtgcg gcggcgacct
     1561 gggtcgagcc cgacgccgag gtgcgcgccg cggcggccgc ctcgatgcgc gcgatcgacc
     1621 gccgcatcgg cctggcgcag accgccggca cgctgttctc cggcctgtcg ctcggctcca
     1681 tcctgctgct cgccgcgctc ggcctggcga tcacctacgg cgtcatgggc gtgatcaaca
     1741 tggcgcacgg cgagctgctg atggtgggcg cctacgccac cttcgtggtg cagggcgtgt
     1801 tccgcagcca cttccccgca tacctcgacc tctacgtgct cgcggcaatc cctgcggcct
     1861 tcctcgccgc cgcgctggtc ggcatcgtca tggagcgcct ggtgctgcgc cacctctacg
     1921 gccgcccgct ggagagcctg ctcgccacct ggggcctgtc actggtgctg atccaggccg
     1981 cgcgcgtgct cttcgggccg cagaacctgg agctcgccaa cccgtcgtgg atgtcgggcg
     2041 gggtcgagct cgccggcggc gtggtgctgc cgtacaaccg catcgtcatc ctcggcttcg
     2101 ccgccttcgt gctggtgctg atctggctga tgatgcagaa gacgcggctg ggcatgttcg
     2161 tgcgcgcggt cacccagaac cggccgatgg cgggctgcgt gggcgtgccc accgcgcggg
     2221 tggacacgct ggcgttcgcg atcggctccg gcgtcgccgg actgggcgga ctggcgctgt
     2281 cgcagatcgc caacgtcggg ccggccatgg gcacgggcta catcgtcgac gccttcatgg
     2341 tggtggtgct cggcggcgtc ggtcagctcg ccggcgcagt gtgggcggcg ctcggcctgg
     2401 gcatcgtcgc caagttcctc gaaggctggg cgggcgcggt cgtggccaag atcctggtgc
     2461 tggtcttcat catcgccttc atccagaagc gtccgcaggg catcttcgcc ctcaagggcc
     2521 gcttcgccga cagctgaggc cgccaccatg cgtacgccct tcaccctccg cctcttccag
     2581 agcatgccgc gcggcggctg gatcgcgctg gcgatcttcg ccgtcgtggc ctggatcggc
     2641 gtgccggtcg cgcacctcgc gctgccggag agtcacccgc tgcacgtctc cgcctacacc
     2701 gtcagcctgc tcggcaagat cctgtgctac atggtggtcg ccgtcgccat ggacctgatc
     2761 tggggctatg ccggcatcct ctcgctcggc cacggtctct tcttcgccct cggcggctac
     2821 gccttcggca tgtacctgat gcgccagatc gggcgcgacg gcagctacgg cgcggacatc
     2881 cccgacttca tggtcttcct cgactggaag gagctgccct ggtactgggc gggctcggac
     2941 tcgctgctgt gggcgctgtt cctggtggtc gcgctgcccg ggctggtcgc cttcgtgttc
     3001 ggctggttcg ccttccgctc gcgcatcaag ggggtgtact tctcgatcat cacccaggcc
     3061 ctgacctatg ccgcgatgct gctgttcttc cgcaacgaga ccggcttcgg cggcaacaac
     3121 ggcttcaccg acttcaagcg catcctgggc tacgacatca cctcgcccgg gatgcgggtg
     3181 acgctgttcg cgctctcggc ggcgctgctg atcgcctgcc tggtgctcgg ccgctacctc
     3241 gtcacctcgc gcttcggccg cgtgctggcg gcgatccgcg acgccgagag ccgggtcatg
     3301 ttcatcggct acaacccgct gcactacaag ctcttcatgt ggacgctgtc ggcgatgctg
     3361 tgcgggctgg cgggcgcgct gtacgtgccc caggtcggca tcatcaaccc gtcggagatg
     3421 tcgccggcga actcgatcga gatcgcggtg tgggtggcgg tgggcgggcg cggcacgctg
     3481 gtgggcgcgg tgctcggcgc cggcatcgtc aacctcgcca agagcgtgtt cacggtctat
     3541 ctgccggaat actggccctt cgtgctcggt ttcctcttca tcgtcgtcac cctctacctg
     3601 cccgatggcg tggtcggcct gtggcgcaag ctgcgcgcgc ggcgcgcggc ggcggcgctc
     3661 gacgacgcct ccgccgcagc gggtgcgggc cgcgcggcgg caatcggcgg aacgccggcc
     3721 gaggcgccgg tcaccgaacg ccaggccgcc cggtccgcca ccgacacccc catcgccaag
     3781 ggagcgaacg catgatcccc accctcgaga tcgaacgcga gagcgcccgc ctcgacgccg
     3841 agcgcgaaaa ccagcgcgag cactgggacg gctcggccgc ggacgggcgg gtgtacaggc
     3901 cgggcgagct cgacctgtcg cacaaggtga tcctctacct cgacgacatc accgtgagct
     3961 tcgacggctt ccgcgccttg aacaagctca gcctgaccat cgacgccggc gagctgcgct
     4021 gcatcatcgg ccccaacggc gccggcaaga ccacgatgat ggacgtcatc accggcaaga
     4081 cgcggcccga ctcgggcacc gccttcttcg gccagaccat cgacctcacc cgcctgaccg
     4141 agcccgagat cgcccacgcc ggcatcggcc gcaagttcca gaagccgacc atcttcgagc
     4201 accacagcgc cttcgagaac ctcgagctgg caatgaaggc cgacaagcgc gtgcgccgca
     4261 ccctgttcgc cagcctcctc gacgacgagc gcgaccgcgt cgccgaggtg ctgcgccaga
     4321 tccgcctcga ccaggccgcc gaccgtcccg ccgggctgct gtcgcacggc cagaagcagt
     4381 ggctggagat cggcatgctg ctgatgcagg agccgcgcct gctgctgctc gacgagccgg
     4441 tggcgggcat gaccgacgac gagaccgagc gcaccgccga gctcttcgtg agcctggccg
     4501 gcaagcactc gctggtggtg gtcgagcacg acatggcctt cgtcgaggcc ctcggcggca
     4561 aggtcacggt gctgtgcgag ggctcggtgc tggcggaggg ggatctggcc acggtgcagg
     4621 cggatccacg cgtgatcgag gtttatctgg gacgctgaac gaacatgctg aaagtcgaca
     4681 cgctcaacca gtactacggc ggcagccaca tcctgcgcgg cctgtccttc gacgtgcccg
     4741 tcggccaggt caccacgctg ctcgggcgca acggcgtggg caagaccacg ctgctaaaga
     4801 ccctcatggg cctcgtgccc gccgccagcg gcagcatttc cttcgacggc cgcgacatca
     4861 cccgcgcgcc gtcctacaag cgcgtcgccg ccggcatcgg cttcgtgccg caggggcgcg
     4921 agatcttccc gcgcctgacc gtcgaggaga acctgctcat gggcctcgcc acccggccgc
     4981 gcggcagcga gatcccgccg cgcatcttcg acatgttccc ggtgctgagg cagatgatgg
     5041 ggcggcgcgg cggcgacctc tccggcggcc agcagcagca gctcgccatc ggccgcgcgc
     5101 tcgccttcgg gccgaagctg ctgatcctcg acgaacccac cgagggcatc cagccctcga
     5161 tcatcaagga catcgagcgc gccatccgca gcctcgccga gaccggcgag atggccatcc
     5221 tgctcgtcga gcagtactac gacttcgcgc gcgcgctcgc cgaccagtac ctggtgatgg
     5281 agcgcggcga gatcgtcatg cgcggcgcgg gggcggacat ggaccgcgac ggggtgcgcg
     5341 aggcgctggc ggtctgagcg ccgccgcgtc gctgcgacac cgcagctccg gcgcgcggcc
     5401 gcaccgtcgc accgcgctgg tgcgaccgca ggcgaacgca ccagcctggg gcgtcgaccg
     5461 tgccccgccg cagcgcgcag gcccaccgcc gcacccgcga cgcccctgga agccccggcc
     5521 ggcgcgcctt cgggaagctg gcccgggtct tgctaagcgt ctcccatgtt cctgcacccg
     5581 ccccccctcg ccgcatccct gctcgcccct gccggcgcca ctgcgcccac gccgtggcgc
     5641 gccggactgc gcctggagta cgagcggcgc ggcgcacgca gcgtgctcgc acgccgcgag
     5701 cacttcggcc cgctgcgcgt gcagcgcgcg ctctacccgg aaggcgaggg cgtctgccac
     5761 accctgctgg tgcacccgcc cgccggcatc gtcggcggcg acgagctgcg ggtggacctg
     5821 cgtgtcggca cggacgcgca cgtgctgctg accaccccgg gcgccggcaa gtggtaccgc
     5881 agcgccggtg cgcgcggcgt gctcgagcag cacatcgcgg tggcgccggg cgcggtgtgc
     5941 gagtggctgc cgcaggagag catcgtgcat gagggcgcag tcgcagggct gtcaacggag
     6001 gtgcgcctgg aaggcgatgc ctgcttcatc ggcagcgaga tgctgtgctt cggccgcacg
     6061 gcctccggcg aacgcttcgc ccacggcgag ctggcgatgc gcacccgcat cgagcgcgac
     6121 ggccggccga tctggctgga gcgcggcgtg gtgcacggcg gcggcgggct gctcgccgcc
     6181 gcgccgggcc tgcagggcca gccggtgagc gccagcctgc tggtcgcctc gccgcgctgc
     6241 gacgaggcct tgcgcgacgc ctggcgcgcg ctcgcgccta ctgcgggcga gggcgcggtg
     6301 agcctgctgc cgggcgtgct ggtggcgcgc tggctggggc cggcctgcga gcccggccgg
     6361 cagtggttcg cccgcctgtg ggcagcggcg cgcccggcag tggcggggcg ggcggcgcac
     6421 acgccgcgga tctggaacac ctgacgagcc atgggcggca ccgcgccgcc acggaggaag
     6481 acgatggaac tgagcccacg cgagaaggac aagctgctgg tgttcaccgc cggcctgctc
     6541 gccgagcgcc ggcgcgcgcg cggtctgctg ctgaactacc cggaggcggt ggcgctgatc
     6601 acctgcgcga tcctcgaggg cgcgcgcgac ggccgcagcg tcgcggagct gatgagcttc
     6661 ggcgcgaccc tgctgacgcg cgccgacgtg atggagggcg tcgccgagat gatccccgac
     6721 atccaggtcg aggcaacctt tcccgacggc accaagctgg tgaccgtgca caacccgatc
     6781 gtgtgaggcg caggtcgatg atccccggag aactcctcgt cgccgacggc gacatcgaac
     6841 tcgccgtcgg ccgcgccacg cgcacgctgg tggtgagcaa caccggcgac cgcccgatcc
     6901 aggtcggctc gcactaccac ttcgccgaga ccaacaccgc gctcgacttc gaccgcgcgg
     6961 cggcgcacgg cttccgcctg aacatcgccg ccggcaccgc ggtgcgcttc gagcccggcc
     7021 agtggcgcac cgtcgagctg gtggcgctgg cgggcgagcg cgaggtgtat ggcttcaacg
     7081 gcctcgtcat ggggcggctg gacgagccgg cgagggcgcc cgccgcgcac cgcggcgaag
     7141 gagacctgtg atggcgaaga tctcgcgccg cgcgtacgcg gagatgttcg gccccacggt
     7201 gggcgaccgg ctgcggctcg ccgacaccgc gctggtggtc gaggtcgagc acgacttcac
     7261 gatctacggc gaggaggtga agttcggcgg cggcaaggtg atccgcgacg gcatgggcca
     7321 gg
//
LOCUS       DAOTIN010000152         7252 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_12286_length_7252_cov_8.663888, whole genome shotgun sequence.
ACCESSION   DAOTIN010000152 DAOTIN010000000
VERSION     DAOTIN010000152.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 7252)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 7252)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7252
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_12286_length_7252_cov_8.663888"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            112..381
                     /locus_tag="P5537_15285"
     CDS             112..381
                     /locus_tag="P5537_15285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004317758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79450.1"
                     /translation="MNTRSLVVVEGTCPESRARQRRDPVGGSIHRAIDAGFRIGRRVR
                     IGRVCGSVIGYNIASSGRFGGASYPLLVETEFGIAKCSMTEVCPA"
     gene            562..969
                     /locus_tag="P5537_15290"
     CDS             562..969
                     /locus_tag="P5537_15290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HRV79451.1"
                     /translation="MSAATTRVVPVSQLAAQPAGGAPLVVLALCAQWCGTCREFHSTL
                     ERLAEARRDIVFAWADVEDDAELVGDLDVENFPTLALFRAGLALHYGVSLPHETVVAR
                     LVETLAAAAPRAAAGLPAEIEELARRLSQPDGG"
     gene            complement(1031..2509)
                     /locus_tag="P5537_15295"
     CDS             complement(1031..2509)
                     /locus_tag="P5537_15295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pili methyl-accepting chemotaxis
                     transducer N-terminal domain-containing protein"
                     /protein_id="HRV79452.1"
                     /translation="MTEPHGRRRSAQRDFLSRCALFSRLRAEQLDELAASGRILELPA
                     HAVLHRPGEPLRQAFVLCSGSVLRYRLLAGEVRKVIELVHRPQLLAPGEVFGAREHES
                     VCEVVAPAIVTVLDVRVLRRMVREDLGFSGRVVEALAHSLHAVEFDVAGHHAGLTGAQ
                     RILDYLVELAGGELPLAGETTVELGAKKKIVAERTGMTPEAFSRSLRELADKGLIVVE
                     RNRIHIQNAALLDTNAGAASEPRRLSFARKLRGREDGELSPGERINLAGRLRVLSQRL
                     AIAWALAAHGIGATDARAQLRQLSAEFERALARLQAIRMGAEPAALLAAVGRAWVPYR
                     AALSAEESEAARTLETSEDFLAAADALTAYAERMGGLQSAHHVNVAGRNRMLSQRIVK
                     LFLFADLATGCDIAALIERSAAEFEANLAELLRDGRALPEVVAQLDEVAKQWRRLLGA
                     LAPSVDRPRRSQQARLVTAEGKRLLRCVDTVVKLYERLTREP"
     gene            complement(2581..4290)
                     /locus_tag="P5537_15300"
     CDS             complement(2581..4290)
                     /locus_tag="P5537_15300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004378435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome D1 domain-containing protein"
                     /protein_id="HRV79453.1"
                     /translation="MLFKWAAVPVLALAMQGAFAEAPAGHGDAALKEYQAGGSPMADV
                     PMHHDINPLAPRMSEPEFEKAKRIFFERCAGCHGVLRKGATGKALTPDLTLEKGLEYL
                     KVFIKFGSPGGMPNWGTSGVLNDEEVDLMARYIQQTPPAPPEYGLKEMGASWKVVVPV
                     EQRPKKKMNDLDLENLFSVTLRDDGKIALIDGASKKIVSILETGYAVHISRMSASGRY
                     LFVIGRDAKINLIDLWMEKPDTVAEIKVGLEARSVESSKAEGWEDKYAIAGTYWPPQF
                     VIMDGDTLKPRKIVSTRGMVTGTQDYHPEPRVAAIVSSHFNPEFFVNVKETGMVYSVD
                     YRDLENLRLKMIEAAPFLHDGGFESKHRYFMDAANASDKIAVIDTKEGKLEKLVSVGK
                     VPHPGRGANFVDPQFGPVWATGHLGDETISLIGTDPEKHPDNAWKVVRTLKGLGGGSL
                     FLKTHPKSKNLWVDTTLNPEENVSQSVAVWDIDNIDKGYELIPIGEWSGIKEGPKRVV
                     QPEYNKAGDEVWFSVWNGADQESAIVVVDDKTRKLKAVIRDPKLITPTGKFNVYNTQH
                     DVY"
     gene            complement(4475..5701)
                     /gene="sstT"
                     /locus_tag="P5537_15305"
     CDS             complement(4475..5701)
                     /gene="sstT"
                     /locus_tag="P5537_15305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004378433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HRV79454.1"
                     /translation="MNQSIASPVSRFFFRTSLVLQIAIGLGCGIALALVAPELARAAG
                     LLGDVFISALKAVAPVLVFVLVASAVASHRQGSETHVRPILLLYLIGTFGAALVGVLA
                     SFAFPTTLVLDAPQVAGTPPGGIVGVLKNLLLNAVSNPVRALMEANFIGILAWAIALG
                     AALRHAGAGTRAAVADLAEAVSKIVRVVIRFAPFGIFGLVGATLTESGLGALLGYGRL
                     LLVIVGSMLFVAFVMNPLLVFWKIRRNPFPLVFTCLRESAVTAFFTRSSAANIPVNLE
                     LCRRLELHEDTYSISIPLGATINMAGAAITIAVMSLAAAHTVGIAVDLPTALLLSVVS
                     ALGACGASGVAGGSLLLIPMACNLFGIPTDVAMQVVAIGFIIGVVQDSVETALNSSTD
                     VLFTAAACQAVAPSAA"
     gene            complement(5774..6277)
                     /locus_tag="P5537_15310"
     CDS             complement(5774..6277)
                     /locus_tag="P5537_15310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004378431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CreA family protein"
                     /protein_id="HRV79455.1"
                     /translation="MKSLTASQPTRGALAATLLALGLALPGAAAAETVGHVDTAFKLI
                     GRNHQVVVEAFDDPSVKGVSCYVSRARTGGLKGTFGLAEDTADASVACRQVGDISFSG
                     PLREQEEVFSQSASILFKKVRIVRMVDPRRNTLVYLVYSDKLIEGSPQNSVTAVPVPA
                     SLPIPLR"
     gene            complement(6426..>7252)
                     /locus_tag="P5537_15315"
     CDS             complement(6426..>7252)
                     /locus_tag="P5537_15315"
                     /EC_number="4.1.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004317762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tryptophanase"
                     /protein_id="HRV79456.1"
                     /translation="IRRVCDEFGLMLVMDASLLADNLHFIKEREEACKDLSIREITRR
                     MADLCDVIYFSARKLGCARGGGMCIRSEELYRRMRGLVPLYEGFLTYGGMSVREMEAL
                     TVGLEETMDEEVINQGPQFIGFMVDELVKRGIPVITPAGGLGCHINAMQFVDHIPQAQ
                     YPAGALASALYIAGGIRGMERGTLSEQREPDGSELFANMELVRLAMPRRVFTLSQVKY
                     AVDRLEWLYANRRLIGGLVFTEEPEILRFFYGRLAPVSDWQNELVAQFRKDFGDSL"
BASE COUNT         1130 a         2503 c         2534 g         1085 t
ORIGIN      
        1 accctggtca cggggtgcgc actttcctgc aggcagcggc tgtggaaagc cctaggctga
       61 ccgtgaagag ggataggact atcgtttccg ctccccagca cagaggtcgc catgaacacc
      121 cgctcgctcg tcgtcgtcga aggaacgtgc cccgagtcgc gcgcccgcca acgccgcgat
      181 ccggtcggag ggtcgatcca tcgcgcgatc gacgccggat tccgcatcgg ccgccgcgtc
      241 cgcatcggtc gcgtgtgcgg cagcgtgatc ggctataaca tcgccagctc cggccgcttc
      301 ggcggcgcct cttacccgct gctggtcgag accgagttcg gcatcgccaa gtgcagcatg
      361 acggaagtct gcccggcctg agccccttgc ccggacgggc gtccaacccg agccatgaac
      421 cccacgcccg tcccctccgc acccgcagca tccacgcccc ccgcctcccc ggccaccgca
      481 tccgggcgcg cctcgtccgc accctccggg cccacgccct gcggcgccat gcccgctcct
      541 cccgcgcctg cgcagccggc cgtgtccgcg gcaaccaccc gggtcgtgcc ggtaagccag
      601 ctcgccgccc agcctgccgg cggcgctccc ctcgtggtgc tcgcgctgtg tgcgcagtgg
      661 tgcggcacct gccgcgaatt ccactccacg ctcgagcgcc tcgccgaggc acggcgcgac
      721 atcgtcttcg cctgggcgga cgtggaggac gatgccgagc tcgtcggcga cctcgacgtg
      781 gagaacttcc ccaccctggc gctgttccgc gccggcttgg ccctgcacta cggcgtcagc
      841 ctgccgcacg agaccgtggt ggcgcgcctg gtcgagacgc tcgccgcggc agcgccccgc
      901 gccgctgcgg gcctgccggc ggagatcgag gagctcgcgc gccggctgtc gcagccggac
      961 ggcggctgag gacggggcag cccggtccgt gccgccgctg cacgcgcagc gccgtgcctg
     1021 cgagccgcgt tcagggctcg cgcgtgaggc gctcgtagag cttcaccacg gtatcgacgc
     1081 agcgcaacag gcgcttgccc tcggccgtca ccaggcgtgc ctgctggctg cggcgtggcc
     1141 ggtccacgct cggcgccagc gcgccgagca ggcgccgcca ctgcttcgcc acctcgtcga
     1201 gctgggcgac gacctcgggt agcgctcgac cgtcgcgcag gagctcggcg aggttggcct
     1261 cgaactccgc agccgagcgc tcgatcagcg cggcgatgtc gcagccggtg gcgagatccg
     1321 cgaagaggaa gagcttgacg atgcgctgcg acagcatgcg gttgcggccg gcgacattga
     1381 cgtggtgcgc cgactgcagc ccgcccatgc gctcggcgta ggcggtgagc gcatccgcgg
     1441 cggcgaggaa gtcctcgctc gtctccagcg tccgcgccgc ctcggactcc tcggcggaca
     1501 gcgccgcgcg atatggcacc caggcacggc cgaccgccgc gagcagggcg gcaggctcgg
     1561 cgcccatgcg gatggcctgc aggcgcgcga gcgcgcgctc gaactcggcg ctgagctggc
     1621 gcagctgtgc gcgcgcatcc gtggcgccga tgccgtgcgc agccagcgcc cacgcgatcg
     1681 ccaggcgctg gctcagcacc cgcaggcggc cggccagatt gatgcgctcg cccggcgaca
     1741 gctcgccgtc ctcgcgcccg cgcagcttgc gcgcgaagct cagccggcgc ggctcgcttg
     1801 ccgccccggc gttggtgtcg agcaaggccg cgttctggat gtggatgcgg ttgcgctcga
     1861 cgacgatcag ccccttgtcg gcgagctcgc gcaggctgcg cgagaacgcc tccggggtca
     1921 tgccggtgcg ctcggcgacg atcttcttct tggcgccgag ttcgaccgtg gtctcgccgg
     1981 ccagcggcag ctcgcccccg gcgagctcga cgaggtagtc gaggatgcgc tgcgcgccgg
     2041 tgagcccggc gtgatggccg gcgacgtcga actcgaccgc atgcaggctg tgcgcgagcg
     2101 cctcgacgac gcggccgctg aagccgaggt cctcgcgcac catgcggcgc agcactcgaa
     2161 catcgagcac ggtgacgatc gccggtgcga cgacctcaca caccgactcg tgctcccgcg
     2221 cgccgaacac ctcgcccggc gccagcagct gcggccggtg caccagctcg atcaccttgc
     2281 gcacctcgcc ggcaagcagg cggtagcgca gcacgctgcc gctgcacagc acgaaggcct
     2341 ggcgcagcgg ctcgcccgga cgatgcagca ccgcatgcgc cgggagctcg agaatgcgcc
     2401 cgctcgcggc gagctcgtcg agctgctccg cgcgcaggcg ggaaaaaagc gcgcagcgcg
     2461 acaggaagtc gcgctgcgcc gagcggcgtc tgccgtgtgg ctccgtcaat cgattcgacc
     2521 tcgcgcccac cgccaccggc cgtgctcggg cggcaagagg ccgcccgagc acgggtcgcg
     2581 tcagtagacg tcgtgttgcg tgttgtagac gttgaacttg ccggtcggcg tgatcagctt
     2641 gggatcgcgg ataaccgcct tgagcttgcg ggtcttgtcg tcgaccacca cgatcgccga
     2701 ctcctggtcc gcaccgttcc agaccgagaa ccagacctcg tcgccggcct tgttgtactc
     2761 cggctgcacg acgcgcttgg gcccttcctt gatgcccgac cactcgccga tcgggatcag
     2821 ctcgtagccc ttgtcgatgt tgtcgatgtc ccacaccgcc accgactggg agacattctc
     2881 ctccggattg agggtggtat cgacccacag gttcttcgac ttcggatggg tcttgaggaa
     2941 cagcgagccg ccgcccaggc ccttgagcgt gcgcaccacc ttccaggcgt tgtccggatg
     3001 cttctcgggg tcggtgccga tcagcgagat ggtctcgtcg ccgaggtggc cggtggccca
     3061 caccgggccg aactgcggat cgacgaagtt ggcgccacgg cccgggtgcg ggaccttgcc
     3121 cacgctgacc agcttctcga gcttgccttc cttggtgtcg atgaccgcga tcttgtccga
     3181 ggcgttggcc gcgtccatga agtagcggtg cttcgactcg aagccgccgt cgtgcaggaa
     3241 gggcgccgcc tcgatcatct tcagcctgag gttctcgaga tcgcggtaat ccaccgaata
     3301 caccatcccg gtctccttca cgttcacgaa gaactccggg ttgaagtgcg aggacacgat
     3361 cgcggccacg cgcggctcgg ggtgatagtc ctgggtgccg gtgaccatgc cgcgggtcga
     3421 cacgatcttg cgcggcttga gcgtgtcgcc gtccatgatc acgaactgcg gcggccagta
     3481 ggtgccggcg atggcgtact tgtcctccca gccttcggcc ttggagctct cgaccgagcg
     3541 cgcctcgagg ccgaccttga tctcggcgac ggtgtcgggc ttctccatcc acaggtcgat
     3601 caggttgatc ttggcgtcgc ggccgatcac gaacaggtag cgcccggagg ccgacatgcg
     3661 cgagatgtgc accgcgtagc cggtctcgag gatgctgacg atcttcttgc tggcgccgtc
     3721 gatgagcgcg atcttgccgt cgtcgcgcag ggtgaccgag aacaggttct cgaggtcgag
     3781 gtcgttcatc ttcttcttcg gccgctgctc gaccgggacg acgaccttcc acgaggctcc
     3841 catctccttg aggccgtact cgggcggcgc cggcggggtc tgctggatgt agcgcgccat
     3901 caggtcgacc tcttcgtcgt tgagcacgcc cgaagtgccc cagttgggca tgccgccggg
     3961 ggagccgaac ttgatgaaga ccttgaggta ttccaggccc ttctccaggg tgaggtcggg
     4021 ggtcagcgcc ttgccggtgg cgcccttgcg cagcacgccg tggcagcccg cgcagcgctc
     4081 gaagaagatg cgcttggcct tctcgaactc gggttcggac atgcgcggcg ccagcgggtt
     4141 gatgtcgtgg tgcatgggca cgtcggccat cggcgaaccg ccggcctggt attccttgag
     4201 cgctgcatcg ccgtggccgg cgggcgcttc ggcaaatgcg ccctgcatcg cgagcgcgag
     4261 gacgggaacg gcggcccact tgaaaagcat cgctggaatc atgttgttgt caccctcgtg
     4321 attggaaaag gtgacgcact ctggcaggtc gccaggggcc gactttgacc gccgtcaacc
     4381 tgatgccatg tgcctgtttt tgaatgcaat tcgcacagcg gatgcttgat tgcaatcaag
     4441 catccgccga caccgggcga ctcgaggctc cggatcaggc cgcggacggg gccacggcct
     4501 ggcaggccgc ggcggtgaac agcacgtcgg tcgaggagtt gagcgcggtc tccaccgagt
     4561 cctgcacgac gccgatgatg aagccgatcg ccaccacctg catggcgacg tcggtgggga
     4621 tgccgaacag gttgcaggcc atcgggatca gcagcagcga gccgcccgcg acaccggacg
     4681 cgccgcaggc gccgagcgcc gacaccacgg acagcagcag cgcggtgggc aggtcgaccg
     4741 cgatccccac cgtgtgcgcg gcggcgaggc tcatcaccgc gatcgtgatc gccgcgccgg
     4801 ccatgttgat cgtggcgccg agcgggatcg agatcgagta ggtgtcctcg tgcagttcga
     4861 ggcggcggca gagctcgagg ttgaccggga tgttggccgc cgagctgcgc gtgaagaagg
     4921 cggtcacggc gctctcgcgc aggcaggtga acaccagcgg gaacggattg cggcgaatct
     4981 tccagaacac cagcagcggg ttcatgacga aggcgacgaa gagcatgctg cccacgatca
     5041 ccagcagcag tcggccgtag ccgagcagcg cgcccaggcc ggactcggtg agcgtggcgc
     5101 cgacgagccc gaagatgccg aagggggcga agcggatgac cacgcgcacg atcttcgaca
     5161 ccgcctcggc gaggtcggcc accgccgccc gcgtgccggc gccggcgtga cgcagcgcgg
     5221 cgccaagcgc gatcgcccac gccaggatgc cgatgaagtt ggcctccatg agcgcgcgca
     5281 ccggattcga gaccgcgttc agcagcaggt tcttcagcac cccgacgatg ccgcccggcg
     5341 gcgtgcccgc gacctggggc gcgtccagca ccagcgtggt gggaaaggcg aagctggcga
     5401 gcacgccgac cagggccgcg ccgaaggtgc cgatcaggta cagcagcagg atcgggcgca
     5461 cgtgggtctc gctgccctgg cggtggctgg caaccgcgga ggcgacgagg acgaagacca
     5521 gcaccggcgc caccgccttg agcgcggaga tgaacacgtc accgagcagg ccggcggcgc
     5581 gcgcgagttc gggtgcgacg agggcgagcg cgatgccgca accgaggccg atggcgatct
     5641 gcagcacgag gctggtccgg aagaagaagc gggaaacggg actggcgatg gactggttca
     5701 tgatgggaga aaagaaaaaa cacgcccgct cccgccgagg ggcggaagga ggcgctacgg
     5761 agaatgcagc ggatcagcgc agcgggatgg ggagcgaggc cgggaccggc accgcggtga
     5821 cgctattctg cgggctgccc tcgatgagct tgtcgctgta gacgagatag accagcgtgt
     5881 tgcgcctggg gtcgaccatg cgcacgatgc gcaccttctt gaacaggatc gaggcactct
     5941 gcgagaacac ctcctcctgc tcgcgcagcg ggccggagaa ggagatgtcg ccgacctggc
     6001 gacaggcaac cgacgcgtcg gcggtgtcct cggcgaggcc gaaggtgccc ttgaggccgc
     6061 cggtgcgcgc acgcgagacg tagcaggaca cgcccttcac cgaggggtcg tcgaaggcct
     6121 cgaccaccac ctggtggttg cggccgatga gcttgaaggc ggtgtcgacg tggcccacgg
     6181 tctcggccgc ggccgcgccg ggcaaggcga ggccgagcgc gagcagcgtg gcggcaagcg
     6241 cgccgcgggt cggctgggat gccgtaaggg acttcatcac gaaggactcc aggatgctgt
     6301 gaagcgacca ttatcgcacc gcagcacggc gccgggaggc ccgctcgggc gcattccgcg
     6361 cgcatgcggg cgcggagcgc tgccggccgg caggtgcgac ccgcccaccg gcagctcagc
     6421 cggcctcaga ggctgtcgcc gaagtccttg cggaactgcg cgacgagctc gttctgccaa
     6481 tcggacaccg gcgccaggcg accgtagaag aagcgcagga tctccggctc ctcggtgaac
     6541 accaggccac cgatcaggcg gcggttggcg tacagccact ccaggcgatc caccgcgtac
     6601 ttgacctgcg acagcgtgaa cacccgccgc ggcatcgcca ggcgcaccag ctccatgttg
     6661 gcgaagagct cgctgccgtc gggctcgcgc tgctcggaga gcgtgccgcg ctccatgccg
     6721 cggatgccgc cggcgatgta tagcgccgag gcgagcgccc ccgccggata ctgcgcctgc
     6781 gggatgtggt cgacgaactg catcgcgttg atgtggcagc ccaggccgcc ggccggggtg
     6841 atcaccggga tgccgcgctt gacgagctcg tccaccatga agccgatgaa ctgcgggccc
     6901 tggttgatga cctcctcgtc catggtctcc tcgaggccca cggtgagcgc ctccatctcg
     6961 cgcaccgaca tgccgccata ggtcaggaag ccctcgtaga gcggcaccag gccacgcatg
     7021 cggcggtaca gctcctcgct gcggatgcac atgccgccgc cgcgcgcgca gccgagcttg
     7081 cgcgcggaga agtagatgac gtcgcagagg tcggccatgc ggcgggtgat ctcgcggatg
     7141 ctcaggtcct tgcaggcctc ctcgcgctcc ttgatgaagt gcaggttgtc ggcgagcagg
     7201 ctggcgtcca tcaccagcat cagcccgaac tcgtcgcaca ccctgcggat gt
//
LOCUS       DAOTIN010000153         7248 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_12297_length_7248_cov_9.625052, whole genome shotgun sequence.
ACCESSION   DAOTIN010000153 DAOTIN010000000
VERSION     DAOTIN010000153.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 7248)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 7248)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7248
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_12297_length_7248_cov_9.625052"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..88)
                     /locus_tag="P5537_15320"
     CDS             complement(<1..88)
                     /locus_tag="P5537_15320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012081251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HRV79457.1"
                     /translation="MAKGKFERTKPHVNVGTIGHVDHGKTTLT"
     gene            complement(137..2236)
                     /gene="fusA"
                     /locus_tag="P5537_15325"
     CDS             complement(137..2236)
                     /gene="fusA"
                     /locus_tag="P5537_15325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HRV79458.1"
                     /translation="MARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVSHKLGEVH
                     DGAATTDWMVQEQERGITITSAAVTCFWKGMDNSYPEHRFNIIDTPGHVDFTIEVERS
                     MRVLDGACMVYCAVGGVQPQSETVWRQATKYKVPRLAFVNKMDRSGANFFKVVDQMKT
                     RLKANPVPVVIPIGAEDTFKGVVDLLKMKAIIWDEASQGMKFEYHDIPAELVGTAEEW
                     RASMVEAAAEANEDLMNKYLEEGELSEEEVIAGLRARTLACEIQPMLCGTAFKNKGVQ
                     RMLDAVIQYLPSPIDIPPVAGVDDDEKEVVRYAKDDEKFSALAFKLMTDPFVGQLTFI
                     RVYSGVLESGSTVLNSVKGKKERIGRILQMHANDREEIKEVLAGDIAAVVGLKDVTTG
                     ETLCDTSAPVILERMVFPDPVIHVAVEPKTKGDQEKMGLALSRLAAEDPSFRVRTDEE
                     SGQTIISGMGELHLEIIVDRMKREFNVEANVGAPQVAYRETIRKAAMDVEGKFVKQSG
                     GRGQYGHVVINLEPAEQGKGYEFVDAVKGGVVPREYIPAVDKGIQETIPNGVLAGFPV
                     VDVKVTLHFGSYHDVDSNENAFKMAGSMAFKEAMRRASPALLEPMMAVVVETPEDYMG
                     NVMGDLSGRRGIVQGMDDIPGGMKEIKAEVPLAEMFGYATQLRSLTQGRATYSMEFKH
                     YSEAPKSVAEAVISSRK"
     gene            complement(2344..2814)
                     /gene="rpsG"
                     /locus_tag="P5537_15330"
     CDS             complement(2344..2814)
                     /gene="rpsG"
                     /locus_tag="P5537_15330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002006497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HRV79459.1"
                     /translation="MPRRREVPKREVLPDPKFGNQDVSKFINVIMQSGKKSVAERIVY
                     GAFDHISSKSGKDPLEVFSSAVANVKPVVEVKSRRVGGANYQVPVEVRPSRRMALSMR
                     WLREAARKRAEKSMAQRLAGELLEASEGRGSAMKKREEVHRMAEANKAFSHYRF"
     gene            complement(2848..3225)
                     /gene="rpsL"
                     /locus_tag="P5537_15335"
     CDS             complement(2848..3225)
                     /gene="rpsL"
                     /locus_tag="P5537_15335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009548400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HRV79460.1"
                     /translation="MPTINQLVRKPRQLEVAKSKVPALEACPQKRGVCTRVYTTTPKK
                     PNSALRKVAKVRLTNGFEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGSL
                     DLQGVKDRKQSRSKYGAKRPKKA"
     gene            complement(3360..>7248)
                     /gene="rpoC"
                     /locus_tag="P5537_15340"
     CDS             complement(3360..>7248)
                     /gene="rpoC"
                     /locus_tag="P5537_15340"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004343151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000345 - cytosolic DNA-directed RNA
                     polymerase complex [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HRV79461.1"
                     /translation="LDMTLRDIERVLYFEAYVVVDPGMTPLNRGQLLTEDDYLAKVEE
                     YGDEFDAVMGAEGIGALLRSLDIDLEAEKLRGDLETTNSEAKIKKFSKRLKVLEAFQQ
                     SGIKPEWMVLQVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKA
                     PDIIVRNEKRMLQEAVDSLLDNGRRGKAMTGANKRPLKSLADMIKGKGGRFRQNLLGK
                     RVDYSGRSVITVGPQLKLHQCGLPKLMALELFKPFIFNKLELMGLATTIKQAKKMVES
                     QEPVVWDILEEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCVAFNADF
                     DGDQMAVHVPLSLEAQMEARTLMLASNNVLSPANGEPIIVPSQDIVLGLYYATREGVN
                     VPGEGMIFTDVSEVKRAYESGQIALHARVTVRLKEADLGPNGERIEKIVRHDTTAGRA
                     ILSEILPAGLPFSVIDKPLKKKEISRLINASYRRCGLRATVIFADKLMQFGYGLATRA
                     GLSIAVKDMLVPNAKHELIRAAEAEVKEIAQQYTSGLVTDGERYNKVVDIWGRCGDQV
                     AKAMMEQLGKEKAQDRFKGLPRAQFWQQVYAGGEKAVAQDVDQESFNAIYMMADSGAR
                     GSAAQIRQLAGMRGLMAKPDGSIIETPITTNFREGLNVLQYFISTHGARKGLADTALK
                     TANSGYLTRRLVDVTQDLVVIEDDCGTREGFNMKALIEGGEVVEPLRERILGRVCVED
                     IVNPDNQETMIEAGSLLDEDAVDLIESLGVDEVKVRTPLTCETRYGLCAQCYGRDLGR
                     GSRVNVGEAVGVIAAQSIGEPGTQLTMRTFHVGGAASRAAAASGVEAKSAGSIRFAGN
                     MRYVANAKGEKIVIARSAELVVADDMGRERERHKLPYGATLLVDDGAPVKAGAQLATW
                     DPHTRPIVTEYTGTVKFENVEEGVTVAKQIDEVTGLSTLVVIDAKRRSTTGSTKGLRP
                     QVKLLDEAGEEVKIAGTEHSVAITFQVGSLITVKDGQQINVGDILARIPQESAKTRDI
                     TGGLPRVAELFEARAPKDAGMLAEYTGTVSFGKETKGKQRLVITEPDGTSHEFLIPKD
                     KHLMVHDGQVVNKGELIVDGPSDPHDILRLQGISELARYIIDEVQDVYRLQGVKINDK
                     HIEVIVRQMLRRVVITDPGDTRFIREEQVERSEVLDENDRVEAEGKLPAQYENVLLGI
                     TKASLSTDSFISAASFQETTRVLTEAAIMGKRDELRGLKENVIVGRLIPAGTGLAYHR
                     SRKAQEEGRDLGAEHAWAPAEEVVETQQDIEAS"
BASE COUNT         1165 a         2350 c         2323 g         1410 t
ORIGIN      
        1 cggtcagcgt ggtcttgcca tggtcgacgt ggccgatggt gccgacgttg acgtgcggtt
       61 tggtacgttc gaacttaccc ttcgccatgt tctcgggtcc ttgagttgag gttgctgaat
      121 aaggttgcgg tctgggttac ttgcggctgc tgatcacggc ctcggccacg ctcttcggcg
      181 cctcggagta gtgcttgaac tccatggagt aggtcgcacg accctgggtc agcgagcgca
      241 gctgggtagc gtaaccgaac atctcggcca gcggcacctc ggccttgatc tccttcatgc
      301 cgccggggat gtcgtccatg ccctggacga tgccgcgacg accggacaga tcgcccatca
      361 cgttgcccat gtagtcttcc ggagtctcga ccaccacggc catcatcggc tcgagcagcg
      421 ccgggctggc gcgacgcatg gcttccttga aggccatgga gccggccatc ttgaacgcgt
      481 tttcgttcga gtcgacgtcg tggtaggagc cgaaatgcag cgtcaccttc acgtccacca
      541 ccgggaagcc ggccagcacg ccgttcggaa tggtttcctg gatgcccttg tcgaccgccg
      601 ggatgtattc gcgcggaacc acgccaccct tgaccgcatc gacgaactcg tagcccttgc
      661 cctgctcggc cggctcgagg ttgatgacga cgtgaccgta ctggccgcga ccgccggact
      721 gcttgacgaa cttgccctcg acgtccatcg cagccttgcg gatggtctcg cggtaggcca
      781 cctgcggtgc gccgacgttg gcctcgacgt tgaactcgcg cttcatgcgg tcgacgatga
      841 tctcgaggtg cagttcgccc atgcccgaga tgatggtctg acccgactct tcgtccgtgc
      901 ggacacggaa cgacgggtct tcagccgcca ggcgcgagag agcgaggccc atcttctcct
      961 ggtcgccctt ggtcttgggc tcgacggcga cgtggatcac cggatccggg aacaccatgc
     1021 gctccaggat caccggggcg ctggtgtcgc acagggtctc gccggtggtg acgtccttca
     1081 gaccaaccac ggcggcgatg tcgcccgcga gcacttcctt gatctcttcg cggtcgttgg
     1141 cgtgcatctg caggatgcga ccgatgcgct ccttcttgcc cttcacggag ttcagcacgg
     1201 tcgagcccga ctcgagcacg ccggaataaa cgcgaatgaa ggtcagctgg ccgacgaagg
     1261 ggtcggtcat cagcttgaac gcgagcgccg agaacttctc gtcgtccttg gcgtagcgca
     1321 cgacttcctt ctcgtcgtca tccacaccgg cgaccggcgg gatgtcgatc ggcgacggca
     1381 gatactggat gaccgcgtcg agcatgcgct gcacgccctt gttcttgaac gcggtgccgc
     1441 acagcatcgg ctggatctcg caggccaggg tacgcgcgcg cagaccggcg atgacctcct
     1501 cctcggaaag ctcgccttcc tcgaggtact tgttcatcag gtcttcgttg gcctcggcgg
     1561 ccgcctcgac catgctggca cgccactctt cggcggtacc gacgagctcg gccgggatgt
     1621 cgtgatactc gaacttcatg ccctgggaag cctcgtccca gatgatcgcc ttcatcttga
     1681 gcaggtcgac gacccccttg aaggtgtctt cggcgccgat cgggatcacc accggaaccg
     1741 gattggcctt gagacgagtc ttcatctggt cgacgacctt gaagaagttc gcacccgagc
     1801 ggtccatctt gttcacgaaa gcgagacgcg gcaccttgta cttggtcgcc tggcgccaca
     1861 ccgtctcgga ctgcggctgc acgccaccca ccgcgcaata caccatgcac gcgccgtcga
     1921 gcacacgcat cgagcgctcc acctcgatgg tgaagtccac gtgtcccggg gtgtcgatga
     1981 tgttgaagcg atgctccgga taggagttgt ccatgccctt ccagaagcag gtcaccgcag
     2041 ccgaggtgat ggtgatgcca cgctcctgct cctgcaccat ccagtcggtc gtggccgcgc
     2101 cgtcgtgcac ctcacccagc ttatggctca cgccggtata gaagaggata cgctcggtcg
     2161 tagtcgtctt gcctgcgtcg atgtgagcgg agataccgat gttgcggtaa cgctcgatgg
     2221 gtgtcttgcg agccacgtta tacctgcctt ctgttgtgcg cgcttttggc acgctgaacg
     2281 aattcttgcg ttagaaaaca atcgagccct tcgcagggcc cgagaaaccg ccaccgaagg
     2341 aaatcagaag cggtagtgcg agaacgcctt gttggcttca gccatgcggt gaacttcttc
     2401 acgcttcttc atggcggaac cgcgaccttc ggaggcttcg agcagctcgc cggcgagacg
     2461 ctgggccatc gacttctcgg cacgcttgcg agcggcctcg cgcagccagc gcatggacag
     2521 cgccatgcgg cgggacgggc gaacctcgac cggaacctgg tagttcgcac caccgacacg
     2581 gcggctcttg acctcgacca ccggcttgac gttcgcgact gcggacgaga agacctcgag
     2641 cggatccttg cccgacttgg acgagatgtg atcgaaagcg ccatagacga tgcgctcggc
     2701 gacggacttc ttgcccgact gcatgatcac gttgatgaac ttggaaacgt cctgattgcc
     2761 gaacttggga tcgggcagga cttcgcgctt gggtacttca cgacgacgcg gcatggcaac
     2821 ctctagctaa atttctgtga ccaacaatca ggctttcttc gggcgcttgg caccgtactt
     2881 cgagcgcgac tgcttgcgat ccttgacgcc ctggaggtcg agcgaaccac ggacgatgtg
     2941 gtaacgcaca cccggaaggt ccttcacacg accgccgcgg atcagcacga ccgagtgctc
     3001 ctgcaggttg tgaccctcgc caccgatgta cgagatgacc tcgaaaccgt tggtcaggcg
     3061 caccttggcg accttacgca gcgccgagtt cggcttcttc ggggtcgtgg tgtagacgcg
     3121 ggtgcagacg ccgcgcttct gcgggcaagc ctcgagggcc ggaaccttgc tcttggcaac
     3181 ttccagttgg cgcggcttgc gaacaagctg attgattgtt ggcatagctt aagaatttcc
     3241 cataagaccg cggcagccca ccatgggccg ccgcgggcgg attattccgg ctgagactga
     3301 ctacgattgg tcagcccaca aaaaagaggc cggagtttag tccgagactg tccgaaaagt
     3361 caactcgcct cgatgtcctg ctgtgtttcc acaacctctt ccgcgggcgc ccaggcgtgc
     3421 tcggcaccga gatcgcggcc ttcttcctgc gccttgcggc tgcggtggta agccaggccg
     3481 gtgcctgccg ggatgaggcg accgacgatg acgttctcct tcaggccgcg cagctcgtcg
     3541 cgcttgccca tgatcgccgc ctcggtcagc acccgggtgg tctcctggaa ggaggccgcg
     3601 gagatgaagg agtcggtcga cagcgacgcc ttggtgatac ccagcagcac gttctcgtac
     3661 tgcgcaggaa gcttgccctc ggcctcgaca cggtcgttct cgtccagcac ctcggagcgc
     3721 tcgacctgct cctcgcggat gaaccgggtg tcgcccggat cggtgatgac cacgcggcgc
     3781 agcatctggc ggacgatcac ctcgatgtgc ttgtcgttga tcttcacgcc ctgcaggcga
     3841 tacacgtcct gcacctcgtc gatgatgtag cgcgcgagct cgctgatccc ctgcaggcgc
     3901 aggatgtcgt gcggatcgga cggtccgtcc acgatcaact cgcccttgtt cacgacctgc
     3961 ccgtcgtgca ccatcaggtg cttgtccttc gggatcagga actcgtgcga ggtgccatcg
     4021 ggctcggtga tcaccagacg ctgcttgccc ttggtttcct tgccgaagga taccgtgccg
     4081 gtgtactcgg cgagcatccc ggcatccttg ggcgcgcgcg cctcgaagag ctcggccacg
     4141 cgcggcagac caccggtgat gtcgcgcgtc ttcgccgatt cctgcgggat gcgtgcgagg
     4201 atgtcgccga cgttgatctg ctggccgtcc ttcacggtga tcagcgaacc gacctggaaa
     4261 gtgatcgcca ccgaatgctc ggtaccggcg atcttgactt cctcgccggc ttcgtcgagc
     4321 agcttgacct gggggcgcaa gcccttggtg ctgccggtcg tggaacggcg cttggcgtcg
     4381 atcaccacca gggtggacag acccgtgacc tcgtcgatct gcttggcgac ggtgacaccc
     4441 tcctccacgt tttcgaactt caccgtaccg gtgtattcgg tcacgatcgg gcgggtgtgc
     4501 ggatcccagg tggcgagctg cgcgccggcc ttgacggggg cgccgtcatc gaccagcagg
     4561 gtcgcgccgt acggcagctt gtggcgctcg cgctcgcggc ccatgtcgtc ggccacgacc
     4621 agctcggcag agcgcgcaat gacgatcttc tctcccttgg cgttggcgac gtagcgcatg
     4681 ttgcccgcga agcggatcga accggccgac ttggcctcga ccccgctcgc cgccgccgct
     4741 cgcgacgccg caccaccgac gtggaaggtc cgcatggtca gctgcgtgcc cggctcgccg
     4801 atcgactgcg cggcgatcac gccgaccgcc tcgcccacgt tcacgcgcga gccacggccg
     4861 aggtcgcggc cgtagcactg cgcgcacagg ccgtagcgcg tctcgcaggt cagcggcgtg
     4921 cgcaccttga cctcgtccac acccaggctc tcgatcaggt cgaccgcgtc ctcgtcgagc
     4981 aggctgcccg cctcgatcat ggtctcctgg ttgtccgggt tgacgatgtc ctcgacgcag
     5041 acgcgaccga ggatgcgctc gcgcagcggc tcgaccacct cgccgccctc gatcagggcc
     5101 ttcatgttga agccttcgcg ggtgccgcag tcgtcctcga tgacgacgag gtcctgcgtc
     5161 acgtccacca ggcggcgggt gaggtagccc gagttcgcgg tcttcagcgc ggtgtcggcc
     5221 agacccttac gggcgccgtg cgtcgagatg aagtactgca gaacgttgag gccttcgcgg
     5281 aagttggtcg tgatcggcgt ctcgatgatg gagccgtccg gcttggccat caggccgcgc
     5341 atgccggcga gctggcggat ctgcgcggcg gaaccccgtg cgcccgagtc ggccatcatg
     5401 tagatcgcgt tgaaggattc ctggtcgacg tcctgcgcga cggccttctc gccgcccgcg
     5461 tacacctgct gccagaactg cgcgcgcgga aggcccttga agcggtcctg ggccttctcc
     5521 ttgccgagct gctccatcat cgccttggcg acctggtcgc cgcagcggcc ccagatgtcc
     5581 acgaccttgt tgtagcgctc gccatcggtc accagacccg aggtgtattg ctgcgcgatc
     5641 tccttgacct cggcctcggc ggcacggatc agttcgtgct tggcgttcgg gacgagcatg
     5701 tccttgaccg cgatcgacag gccggcgcgc gtcgccaggc catagccgaa ctgcatcagc
     5761 ttgtcggcga agatcaccgt tgcacgcaga ccgcagcgcc gatacgaggc gttgatgagc
     5821 ctggagatct ccttcttctt cagcggcttg tcaatcacgc tgaagggcag gccggcaggc
     5881 aggatctcgg acaggatggc gcggccggcg gtggtgtcgt ggcgcacgat cttctcgatg
     5941 cgctcgccgt tgggccccag gtcggcttcc ttcaggcgca cggtgacgcg cgcgtggagg
     6001 gcgatctggc cggactcgta ggcacgcttc acctcggaca cgtcggtgaa gatcatgcct
     6061 tcgccaggca cgttcacgcc ttcgcgggta gcgtagtaca ggccgagcac gatgtcctgc
     6121 gagggcacga tgatcggctc gccgttggcg ggcgagagca cgttgttgga cgccagcatc
     6181 agggtgcggg cttccatttg cgcctcgagc gacagcggca cgtggacggc catctggtcg
     6241 ccgtcgaagt cggcgttgaa ggccacgcag accagcgggt ggagctggat cgccttgccc
     6301 tcgatcagca ccggctcgaa ggcctggatg ccgaggcggt gcagggtcgg cgcgcggttc
     6361 agcaacaccg gatgctcgcg gatcacctcc tcgaggatgt cccacaccac cggctcctgc
     6421 gactccacca tcttcttggc ctgcttgatg gtcgtggcca gccccatcag ctcgagcttg
     6481 ttgaagatga agggcttgaa cagctcgagc gccatcagct tgggcaggcc gcactggtga
     6541 agcttgagct gcgggcccac ggtgatgacg gaacggccgg agtagtccac gcgcttgccg
     6601 agcaggttct ggcggaagcg gccgcccttg cccttgatca tgtcggccag cgacttgagc
     6661 ggacgcttgt tggcgccggt catcgccttg ccgcggcggc cgttgtcgag cagcgagtcg
     6721 acggcttcct gcagcatgcg cttctcgttg cgcacgatga tgtcgggcgc cttgagctcg
     6781 agcaggcgct tgaggcggtt gttgcggttg atgacgcggc ggtagaggtc gttgaggtcg
     6841 gacgtggcga agcggccgcc gtccagcggc accagcggac gcaggtcagg cggcagcacc
     6901 ggcagcacct gcagcaccat ccactcgggc ttgatgcccg attgctggaa ggcctcgagc
     6961 accttcaggc gcttggagaa cttcttgatc ttggcctcgg agttggtggt ctccaggtcg
     7021 ccacgcagct tctccgcctc gaggtcgatg tcgagcgagc gcagcagcgc gccgatgccc
     7081 tcggcaccca tcaccgcgtc gaattcgtcg ccatattcct cgaccttggc gaggtagtcg
     7141 tcctcggtca gcagttggcc gcggttgagc ggcgtcatgc cagggtcgac gacgacgtag
     7201 gcctcgaagt acagcacgcg ctcgatgtcg cgcagggtca tgtcgagc
//
LOCUS       DAOTIN010000154         7143 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_12521_length_7143_cov_9.012839, whole genome shotgun sequence.
ACCESSION   DAOTIN010000154 DAOTIN010000000
VERSION     DAOTIN010000154.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 7143)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 7143)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7143
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_12521_length_7143_cov_9.012839"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            35..1207
                     /locus_tag="P5537_15345"
     CDS             35..1207
                     /locus_tag="P5537_15345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 TIM barrel-domain
                     containing protein"
                     /protein_id="HRV79462.1"
                     /translation="MIAFGAAPLHAAPADAKWKGAAFEGDRASLVRLAAAGARVVRVY
                     RQSDAWVLDEAQRLGLKVVMGLWLEHPRHGFDYADARAVRAQEDAVLDFVARYRHHPA
                     LLAWGVGNEIETAVADPLPLWREVDRLASRIRRLDPEHPTMMVVADTGMDAFRALAGC
                     CPNVDLLGINVYAGAVFDLPQRLRDAGIAKPVVIAELGPLGQWQAGRKPWGAPVELTS
                     TEKARFFTEALAFLDRQAQIRGVFPFLWGAKQEQTATWHGLLLADGSATAMSDALAAA
                     WGRPVARPAPHIRGIGIGADEFAPGAEIGAGVDAVAHDGGALATEWVVHAEATDLRKG
                     GDAERPPARIDVRVLHADAASVRFVAPTQPGAYRLFITVRDRDGKAATANLPFRVR"
     gene            1351..3762
                     /locus_tag="P5537_15350"
     CDS             1351..3762
                     /locus_tag="P5537_15350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HRV79463.1"
                     /translation="MSAPLTPPAPLPAERLVARCDPALLGIGSSAELPELDVARIHGR
                     AVDAIRLGLDIRAEGYNLFVLGDPGSGRHELVRRLLEDVRGRGEAPADWCYAWNFANA
                     SQPRLLRLPCGRGPALRDDLARFVEELVPAIGAVFESEEHRNRIEALQEEAKTREESA
                     LRSLGDEAQRLGVALLRTPHGFAFLPMKDEGSTLTQEEFEKLPEPRQHELGEHIRALH
                     ERLHRLMGDFPRWRHELQNRMRDAGREAIRATVTHMVDELKVRHANLPEVCAHLDAVL
                     VDVVASGESLRATPHTDEDSESLTYTGSISVQRYLVNLLVANPADGARPMVYEDHPTL
                     QNLVGRIDHLVHMGTLVSNFTLIRAGALHRANGGFLVLDALKLLSQPFAWEGLKRALQ
                     SERLRIESLSELIGVTGSVQLEPEPMPLELKVVLIGDRLTYYLLGQYDPEFAALFRIN
                     ADMESEIERSADNTAAYARLLASLARRAGLPPLAAPALARLIEHAARLAADAERLSTR
                     TQPLDDRLREAAHFALAAGAARIEREHVDAAIAAHRRRHERIRLSHLDQILRGQWLID
                     TAGSHVGQVNGLAVVPLGEDRFAHPQRITATVRAGAGEIIDIEREVKLGGPIHSKGVL
                     ILSAFLAARFGWMLPLSLKASLVFEQSYGGVEGDSASLAELVALLSALSGVAVKQSLA
                     VTGSVNQFGVVQPVGGINEKIEGFFELCAARGLDGGQGVLIPRANVCHLMLRDEVVEA
                     VRAGRFAVWAVADADEAVELLTGLPAGQPAADGSMPAGTVNARAVDGLRKLAALHRRG
                     KPRDG"
     gene            complement(3772..5517)
                     /locus_tag="P5537_15355"
     CDS             complement(3772..5517)
                     /locus_tag="P5537_15355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004379176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter assembly complex family protein"
                     /protein_id="HRV79464.1"
                     /translation="MRAALRRGLCPAALALTLAAGGALAQETLEVRLQAPDELRPLLE
                     RHVRLLRQEALALPEEPADRSAMTRRARREVAGLLATEGYFSPRVRFDRSDARDWLLE
                     VEPGPRTEIAQVELQFVGEIATSGPGGSAYLDLLRAGWSLPVGAPFSQGGWDGAKQAL
                     LDAVAARRYAAARIVDSRAEIDPESARATLRVRIDSGPTFYLGELDVEGLEHLPADLV
                     ERYSQLEPGSPYDREALLAFQTELQNTPHFGSVIVDIERDPALSAAVPVRVRVTEALP
                     RYAGAGAGYSTNTGARVELSYRDSNLRKRGWEFSSGLRIEERRQALFADVFLPPRGRD
                     RDSFGALYEASDLEGLKIDSQALGAARTTLRGDIETQLALRLQHENIEPAGAPSRSTN
                     TLSANWTWKKRAVDNVLDPTSGYVLEFQVGGGSKTLLSDQDFLRLYSRVARYQPVRGT
                     DVFILRGEAGVTLADSREGVPQDFLFRSGGAQSVRGYDYQSLGVKEGNATVGGRYLAT
                     ASAEYVRWFQPQWGAAAFVDAGDAADTRADYDLRVGYGIGARWRSPAGPLAIDLAWGH
                     QERSLRLHFGVAVAF"
     gene            complement(5534..6535)
                     /locus_tag="P5537_15360"
     CDS             complement(5534..6535)
                     /locus_tag="P5537_15360"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011236482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 fructose-bisphosphatase"
                     /protein_id="HRV79465.1"
                     /translation="MRRVTLTQFLIEQQRAGRITADLRLLIEVVARAVKAISVNVSKG
                     ALAGVLGEAGTDNVQGEAQKKLDVIANEILLQANEWGGHLAGMASEEVETICQIPFDL
                     PKGGFLLLFDPLDGSSNIDVNISVGTIFSVLRNPPGGSDPTEESFLQPGREQVAAGYA
                     VYGPSTQLVLTVGNGVHAFTLDREMGSFIYTQPFMTIPADTQEFAINASNARHWEAPV
                     KRYVDEMLQGKEGPLGKDYNMRWVASMVADVHRILTRGGVFMYPMDEKCRRQGGKLRL
                     MYEANPMAMLVEQAGGAASTGRERILDVMPERLHQRVPVILGSRNEVERVAGYHEGA"
     gene            6689..>7143
                     /locus_tag="P5537_15365"
     CDS             6689..>7143
                     /locus_tag="P5537_15365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004322115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HRV79466.1"
                     /translation="MHVMVLGAGLSGVTTAWYLTRAGFQVSLVDRQPGAGLETSFANG
                     GQISISHPEPWANPGAPAQVLRWLGRADAPLKFRPRRDLAQWTWGLRFLLECLPARAH
                     RNTVAIAALALASAQRLRALRAELGLEYDQLERGILHLFYSRAEFAKAPA"
BASE COUNT          977 a         2676 c         2509 g          981 t
ORIGIN      
        1 tcaagtgcgc ttcctgttaa cttttttctg cgccgtgatc gctttcggcg cagctcccct
       61 gcacgcagcc cccgcggacg cgaagtggaa gggcgccgcc ttcgagggtg atcgcgccag
      121 cctcgtccgc ctcgccgccg cgggcgccag ggtggtgcgc gtctaccgcc aatccgacgc
      181 ctgggtgctc gacgaggcgc agcgcctcgg cctcaaggtg gtgatggggc tgtggctgga
      241 gcatccgcgc catggcttcg actacgccga cgcgcgggcg gtgcgggcgc aggaagacgc
      301 cgtgctcgac ttcgtcgccc gctaccgcca ccatcccgcc ctgctcgcct ggggcgtggg
      361 caacgagatc gagaccgccg ttgccgaccc cctgccgctg tggcgcgaag tggatcggct
      421 ggccagccgg atcaggcgcc tcgaccccga gcaccccacc atgatggtgg tcgccgacac
      481 cggcatggac gccttccgcg cgctcgccgg ctgctgtccg aatgtggatc tgctcggcat
      541 caacgtctat gcaggcgccg tgttcgacct gccgcagcgc ctgcgcgacg ccggcatcgc
      601 caagccggtg gtgatcgccg agctcggccc gctcgggcag tggcaggccg gacgcaagcc
      661 ctggggcgcg ccggtcgagc tcaccagcac cgagaaggcg cgcttcttca ccgaggcgct
      721 cgccttcctc gaccggcagg cgcagatccg cggcgtcttc cccttcctgt ggggggccaa
      781 gcaggagcag accgcgacct ggcatgggct gctgctcgcc gacggcagcg ccaccgcgat
      841 gagcgacgcg ctcgccgcgg cctgggggcg gccggtggca aggcctgcgc cgcacatccg
      901 cggcatcggc atcggcgccg acgagttcgc ccctggcgcg gagatcggcg ccggcgtcga
      961 tgccgtggcg cacgacggcg gcgcgctcgc caccgagtgg gtcgtgcatg ccgaagccac
     1021 cgacctgcgc aagggcggcg acgccgagcg cccgccggcg cgcatcgacg tgcgcgtgct
     1081 gcacgccgac gccgccagcg tgcgcttcgt cgccccgacg caacccggcg cctaccgcct
     1141 cttcatcacc gtgcgcgacc gcgacggcaa ggcggcgacg gcgaacctcc cgttccgggt
     1201 gcgctgagcg agacatcgcc cgcgccggct tcgcctgcct cgcaccggcc ccgtccgcac
     1261 tcgccggccc gcccttcctg gcttggcccg ccgccccgcc ccgggggtaa gatgccccgc
     1321 acgagaaccc ccagcccagg aggcgcgccc atgtccgctc cactcacgcc gccggcgccc
     1381 ttgccggccg agcgcctggt ggcccgctgc gacccggcgt tgctcggcat cggatcctcc
     1441 gccgagctgc ccgagctcga cgtcgcccgc atccacggcc gcgcggtgga tgcgatccgg
     1501 ctcggcctcg acatccgcgc cgagggctac aacctgttcg tgctcggcga ccctggcagc
     1561 ggccgccacg agctcgtccg ccgcctcctc gaggacgtgc gcggccgcgg agaagcgccc
     1621 gcggactggt gctacgcgtg gaacttcgcc aacgcttccc agccacggct gctgcgcctg
     1681 ccctgcggcc gcggcccggc gctgcgcgac gacctcgcgc gtttcgtcga ggagctggtg
     1741 ccggcgatcg gcgcggtgtt cgagagcgag gagcaccgca accgcatcga ggccttgcag
     1801 gaagaggcca agacgcgcga ggagagcgcc ctgcgcagcc tcggcgacga ggcccagagg
     1861 ctcggcgtgg cgctgctgcg cacaccgcac ggcttcgcct tcctgccgat gaaggacgag
     1921 ggcagcacgc tcacccagga ggagttcgag aagctgcccg agcctcgcca gcacgagctc
     1981 ggcgagcaca tccgcgcgct gcacgagcgc ctgcaccgcc tgatgggcga cttcccgcgc
     2041 tggcggcacg agttgcagaa ccgcatgcgc gacgccgggc gcgaggccat ccgcgccacc
     2101 gtcacccaca tggtcgacga gctcaaggtc cgccacgcca acctgcccga ggtgtgcgcg
     2161 catctggacg cggtgctcgt cgacgtcgtc gccagcggcg agtcgctgcg cgcgacgccg
     2221 cacaccgacg aggacagcga gtcgctgacc tacaccggca gcatcagcgt gcagcgctac
     2281 ctggtcaatc tgctcgtcgc caaccccgcc gacggcgccc gaccgatggt gtacgaggac
     2341 caccccacgc tgcagaacct ggtcgggcgc atcgaccacc tcgtgcacat gggcacgctg
     2401 gtgagcaact tcaccctgat ccgcgccggc gcgctgcacc gcgccaacgg cggcttcctg
     2461 gtgctcgacg cgctcaagct gctgtcccag cccttcgcct gggaggggct caagcgcgcg
     2521 ctccagtcgg agcgcctgcg catcgagtcg ctctccgagc tgatcggcgt gaccggttcg
     2581 gtgcagctcg agcccgagcc catgccgctc gagctcaagg tcgtgctgat cggtgatcgc
     2641 ctcacctact acctgctcgg ccagtacgac cccgagttcg ccgcgctctt ccgcatcaac
     2701 gccgacatgg agagcgagat cgagcgctcg gcggacaaca ccgccgccta tgcgcgcctg
     2761 ctcgccagcc tggcgcggcg cgccggcctg ccgcccttgg cggcgccggc gctggcgcgg
     2821 ctgatcgagc acgcggcgcg cctcgccgcc gacgccgagc gcctgagcac gcgcacccag
     2881 ccgctcgacg accgcctgcg cgaggcggcc cacttcgccc tcgccgccgg cgccgcgcgc
     2941 atcgagcgcg agcacgtcga cgccgcgatc gcggcccatc gccgccgtca cgagcgcatc
     3001 cgcctgagcc acctcgacca gatcctgcgc ggacagtggc tgatcgacac cgccggcagc
     3061 cacgtcggcc aggtcaacgg cctggcggtg gtgccgctcg gcgaggaccg cttcgcccac
     3121 ccgcagcgca tcaccgccac ggtgcgcgcc ggcgctggcg agatcatcga catcgagcgc
     3181 gaggtcaagc tcggcgggcc gatccactcc aagggcgtgc tgatcctgtc cgccttcctc
     3241 gccgcgcgct tcggctggat gctgccgctc tcgctcaagg cgagcctggt cttcgagcag
     3301 tcctacggcg gcgtcgaggg cgacagcgcc tcgctcgccg agctggtggc cttgctgtcg
     3361 gcgctctcgg gcgtggcggt gaagcagtcg ctcgcggtga ccggctcggt gaaccagttc
     3421 ggcgtcgtgc agccggtggg cggcatcaac gagaagatcg agggcttctt cgagctgtgc
     3481 gccgcgcgcg gcctcgacgg cgggcaaggg gtgctgatcc cgcgcgccaa cgtctgccac
     3541 ctgatgctgc gcgacgaggt ggtcgaggcg gtccgggccg ggcgcttcgc ggtgtgggcg
     3601 gtggccgacg ccgacgaggc ggtggagctg ctcaccggcc tgcccgccgg ccagccggcg
     3661 gccgacggca gcatgccggc aggtaccgtc aatgcgcgcg ccgtggacgg cctgcgcaag
     3721 ctggccgcgc tgcaccgccg cggcaagccc cgcgacggct gagcgccagg ctcagaacgc
     3781 caccgcgacg ccgaagtgca gccgcaggct gcgctcctgg tggccccagg cgagatcgat
     3841 cgcgagcgga cccgcggggc tgcgccagcg cgcaccgatg ccgtagccga cgcgcaggtc
     3901 gtagtccgcg cgggtgtcgg cggcatcccc cgcatcgacg aaggcggccg cgccccactg
     3961 cggctggaac cagcgcacgt actcggcgct cgcggtcgcg aggtagcggc caccgaccgt
     4021 ggcgttgccc tccttcacgc ccaggctctg gtagtcgtag ccgcgcaccg actgcgcgcc
     4081 gccgctgcgg aagaggaagt cctgcggcac gccctcgcgg ctgtcggcca aggtcacgcc
     4141 ggcctcgccg cgcaggatga acacgtcggt gccgcgcacc ggctggtagc gcgcgacgcg
     4201 cgagtagaga cgcaggaagt cctggtcgga gagcagcgtc ttgctgccgc cgccgacctg
     4261 gaactccagc acgtagccgc tcgtggggtc gagcacgttg tcgaccgcgc gcttcttcca
     4321 cgtccagttc gcgctcaggg tgttggtcga gcgcgagggg gcgccggccg gctcgatgtt
     4381 ctcgtgttgc aggcgcagcg cgagctgggt ctcgatgtcg ccgcgcagcg tggtgcgcgc
     4441 ggcgccgagc gcctgggagt cgatcttgag gccttcgagg tcgctcgcct cgtagagcgc
     4501 gccgaagctg tcgcggtcgc gcccgcgcgg aggcaggaag acatccgcga acagcgcctg
     4561 gcggcgctcc tcgatgcgca ggccggagga gaactcccag ccgcgcttgc gcaggttgga
     4621 gtcgcggtag ctgagctcga cgcgcgcgcc ggtgttggtc gaatagcccg cacccgcgcc
     4681 ggcataacgc ggcagcgcct cggtgaccct cacccgcacc ggcaccgcgg ccgacagcgc
     4741 cgggtcgcgc tcgatgtcga cgatcaccga accgaagtgc ggggtgttct gcagctcggt
     4801 ctggaaggcg agcagcgcct cgcggtcgta gggcgagccg ggctcgagct ggctgtagcg
     4861 ctcgacgagg tcggcgggca ggtgctccag gccctcgacg tcgagctcgc cgaggtagaa
     4921 cgtcggtccg ctgtcgatgc gcacgcgcag ggtggcgcgc gcgctctcgg ggtcgatctc
     4981 ggcgcggctg tcgacgatgc gcgccgcggc atagcggcgt gccgcgaccg catcgagcag
     5041 cgcctgcttg gccccgtccc agccaccctg gctgaagggc gcgccgaccg gcaggctcca
     5101 gcccgcgcgc agcaggtcca ggtacgcgct gccgccgggc ccggaggtgg cgatctcgcc
     5161 gacgaactgc agctcgacct gggcgatctc ggtgcgcggg ccgggctcca cctcgagcag
     5221 ccagtcgcgc gcgtcgctgc gatcgaagcg cacccgcggc gagaagtagc cctcggtggc
     5281 gagcaggccc gccacctcgc gacgcgcgcg ccgggtcatc gccgagcgat cggccggctc
     5341 ctcgggcagt gcgagcgcct cctggcgcag cagccgcaca tggcgctcga gcagcggccg
     5401 cagctcgtcg ggcgcctgca ggcgcacctc gagggtctcc tgtgccagcg caccgccagc
     5461 cgccagcgtc agggccagcg cggcgggaca caggccccgg cgcagcgcag ctcgcactcc
     5521 cgagcgcacg cgctcaggcc ccctcgtgat agcccgccac gcgctcgact tcgttcctcg
     5581 agcccaggat caccggcacg cgctggtgca ggcgctccgg catcacgtcg aggatgcgct
     5641 cgcgcccggt ggaggccgca ccgccggcct gctcgaccag catcgccatc gggttggcct
     5701 cgtacatcag gcgcagcttg ccgccctgcc tgcggcactt ctcgtccatc gggtacatga
     5761 acacgccgcc gcgggtcagg atccggtgca cgtcggcgac catcgaggcc acccagcgca
     5821 tgttgtagtc cttaccgagc gggccttcct tgccctgcag catctcgtcg acgtagcgct
     5881 tgaccggcgc ctcccagtgg cgcgcgttgg aggcgttgat ggcgaactcc tgggtgtcgg
     5941 ccgggatggt catgaagggc tgggtgtaga tgaagctgcc catctcgcgg tcgagcgtga
     6001 aggcatgcac gccgttgccc acggtgagca cgagctgggt ggacgggccg tacaccgcat
     6061 agccggccgc gacctgctcg cgaccgggct gcaggaagct ctcctcggtc gggtccgagc
     6121 cgcccggcgg gttgcgcagc accgagaaga tggtgccgac ggagatgttg acgtcgatgt
     6181 tggacgagcc atcgagcgga tcgaagagca gcaggaagcc gcccttgggc aggtcgaagg
     6241 ggatctggca gatggtctcg acctcctcgg aggccatgcc ggcgaggtgg ccgccccact
     6301 cgttggcctg cagcaggatc tcgttggcga tcacgtcgag cttcttctgc gcctcgccct
     6361 gcacgttgtc ggtgccggcc tcgccgagca cgccggcgag cgcgcccttg gacacgttga
     6421 cgctgatcgc cttgaccgcg cgagcgacaa cctcgatcag caggcgcagg tcggcggtga
     6481 tgcggccggc gcgctgctgc tcgatgagga actgggtaag ggtgactcgg cgcatgacaa
     6541 ggctccacga cattgaacgg aacggacaag gcaggattat cgcggttccg cgccacgagc
     6601 gcacgggccg cgacgcccga aaccacgaga ctgcagccgc ggccgccgag gcgctatcat
     6661 cggcaccccc catccgcgtt tccacttcat gcacgtcatg gttctcggcg ccggcctgtc
     6721 cggcgtcacg accgcctggt acctgacccg cgccggcttc caggtcagcc tggtcgaccg
     6781 ccagcccggc gccggactcg agaccagctt cgccaacggc ggacagatct cgatcagcca
     6841 tcccgagccc tgggccaacc ccggcgcgcc tgcgcaggtg ctgcgctggc tcgggcgcgc
     6901 cgacgcgccg ctgaagttcc gcccgcgccg cgacctcgcg cagtggacct ggggcctgcg
     6961 cttcctgctc gaatgcctgc ccgcgcgcgc gcaccgcaac accgtggcga tcgccgcgct
     7021 cgcgctcgcc agcgcgcagc gcctgcgcgc actgcgcgcc gagctcgggc tcgagtacga
     7081 ccagctcgag cgcggcatcc tgcacctgtt ctacagccgc gcggagttcg ccaaggcgcc
     7141 cgc
//
LOCUS       DAOTIN010000155         7080 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_12654_length_7080_cov_9.061495, whole genome shotgun sequence.
ACCESSION   DAOTIN010000155 DAOTIN010000000
VERSION     DAOTIN010000155.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 7080)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 7080)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7080
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_12654_length_7080_cov_9.061495"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..880)
                     /locus_tag="P5537_15370"
     CDS             complement(<1..880)
                     /locus_tag="P5537_15370"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="HRV79467.1"
                     /translation="MTVKAYGARAGDLPLEAMEITRRAPGPHDVQIEIAFCGVCHSDL
                     HQVRSEWPGTLYPCVPGHEIVGRVSAVGAHVKGFTAGDLVGVGCIVDSCQHCEDCDAG
                     LENYCDDMVGTYNSPIADAPGHTLGGYSQRIVVHERYVLRIRHPEDQLAAVAPLLCAG
                     ITTWSPLRHWKVGPGHKVGILGIGGLGHMGVKLAHALGAHVVAFTTSESKRAAALALG
                     ADEVVVSRDEDAMKAQRKSLDFILDTVAAPHDLDAFLALLKRDGTMSLVGAPASPHPA
                     PQVFHLIMKRRKLAGSM"
     gene            complement(1394..2731)
                     /locus_tag="P5537_15375"
     CDS             complement(1394..2731)
                     /locus_tag="P5537_15375"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HRV79468.1"
                     /translation="MKLSIFGTGYVGLVSGACLAEVGHDVLCMDVDQAKIDRLRAGTI
                     PIWEPGLQPIVERNLAEGRLRFTTDTAEAVQHAEVQFIAVGTPPDEDGSADLQYVLAV
                     AEEIARHMPAYRVIVNKSTVPVGTAEKVAERIAQILAARGETIAFDVVSNPEFLKEGA
                     AVADFLKPDRILVGTRSARAQERMREIYEPFNRNHERTLFTDVRSAELTKYAANAMLA
                     TRISLMNELANLAERLDADIEEVRKGIGADPRIGYHFIYPGCGYGGSCFPKDVQALGR
                     IADQVGYDAPLLRAVETVNQRQKNTLFAKLAHHFGGPDGLAGRTVAVWGLAFKPNTDD
                     LREAPSRSLIEALWQHGARVQAYDPVAMDETRRIYGPRADLALASHKYSVLEGADALA
                     ICTEWQQFRAPDFDEMATLLQTKVIADGRNLYNPERLRAAGWHYYSVGRPAAT"
     assembly_gap    3113..3212
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(3491..4069)
                     /locus_tag="P5537_15380"
     CDS             complement(3491..4069)
                     /locus_tag="P5537_15380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceI family protein"
                     /protein_id="HRV79469.1"
                     /translation="MNRITRLTAALLVSAAAASPALAAPQTYVVDSTHTFPSFSYSHF
                     GMSIQMSKFDKTTGTVTLDKEAKTGAVEVTIDMKSVSTGYAAFDEHIQGEDFLDTAKY
                     PTATFKSTKVSFDGDKPATIDGELTIKGVTKPVTLKVNHFATMPHPMLKKDAIGANAS
                     TVIKRSEFNAGKYAPNVGDEVTITVSLEAVQN"
     gene            complement(4192..4752)
                     /locus_tag="P5537_15385"
     CDS             complement(4192..4752)
                     /locus_tag="P5537_15385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceI family protein"
                     /protein_id="HRV79470.1"
                     /translation="MKRIALALLASFAFAATAAHAVEYGKVQPDKSRIAFDYQQMGVA
                     MQGTFGKFVSELRFDPAAPQSASARIEVDLASVDTGSEEGDEEVARKTWFDTKGFPVA
                     RFESSAVKPLGGDKYEVAGKLTIKGTTRDVVVPATFTVQGGGGVFEGALTIRRGDFSI
                     GEGAWKAFDVVANDVVIRFSITAAAR"
     gene            complement(4792..5328)
                     /locus_tag="P5537_15390"
     CDS             complement(4792..5328)
                     /locus_tag="P5537_15390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004308561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0022904 - respiratory electron transport
                     chain [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b"
                     /protein_id="HRV79471.1"
                     /translation="MDTHYTATAKLLHWLIALMIFGMLGFGFYMTGLDLSPTKLELYS
                     WHKWAGVTVFVLVLVRLAWRIGHKPPALPAHMPAIERLAAHAGHHLLYVLMLAIPLSG
                     WLMSSAKGFQTVWFGVLPLPDLLAKDKALGNLLETVHFVLNYTLIAVLLGHVGAALKH
                     HFIDRDDVLIRMLPRRKG"
     gene            complement(5975..6736)
                     /locus_tag="P5537_15395"
     CDS             complement(5975..6736)
                     /locus_tag="P5537_15395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HRV79472.1"
                     /translation="MPRSATPVGERPFHIDPSTGSPVTELERLCRLLARASLFNGLAC
                     EDIVRFARGVREVRVARGEILFHRGDPCHGFHLILDGQIKLAFTSAEGNEKVVDILYA
                     GRSFGEAVMFMDKPYVVMAQALTDATLLHIGKQIFFEEMSGDPVFCRKIIAGLAQRLH
                     LLMADVESYSLRSGRDRVVGYLLREEEREGDGVSEGAVSLRLPTSKGTIASRLNLTQE
                     HFSRILNELTGAGLIHVEGRTIHIPDIGRLRRSLG"
     gene            complement(6741..>7080)
                     /locus_tag="P5537_15400"
     CDS             complement(6741..>7080)
                     /locus_tag="P5537_15400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004333947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="nitric oxide reductase"
                     /protein_id="HRV79473.1"
                     /translation="AIKPGYYTRLGAAIRHATTILDRQRAARRILLILSDGKPNDLDL
                     YDGRYGIEDTRVAVVEARNRGVVPFCVTIDREGASYLPHLFGPAGYAVIRQPDELPAR
                     LPMFYAQLTR"
BASE COUNT         1015 a         2115 c         2703 g         1147 t
ORIGIN      
        1 tcatcgagcc ggcgagcttg cgccgcttca tgatgaggtg gaagacctgc ggcgcggggt
       61 ggggcgaggc cggggcgccg accaggctca tcgtgccgtc gcgcttgagc agcgcaagga
      121 aggcgtcgag gtcgtgcggg gcggcgacgg tgtcgaggat gaagtccagc gacttgcgct
      181 gcgccttcat cgcgtcctcg tcgcgcgaca ccacgacttc gtcggcgccg agggcgagcg
      241 cggccgcacg cttggactcc gaggtggtga aggcgaccac gtgcgcgccc agcgcgtgcg
      301 cgagcttgac acccatgtgg cccagcccgc cgatccccag gatgcccacc ttgtggcccg
      361 ggccgacctt ccagtggcgc agcggcgacc aggtggtgat gcccgcgcac agcagcggcg
      421 ccaccgcggc gagctggtcc tcggggtggc ggatgcgcag cacgtagcgc tcgtgcacca
      481 cgatgcgctg cgagtagccg cccagggtgt ggccgggggc gtcggcgatc gggctgttgt
      541 aggtgccgac catgtcgtcg cagtagttct ccaggccggc gtcgcagtcc tcgcagtgct
      601 ggcagctgtc gacgatgcag ccgacgccga cgaggtcgcc ggccgtgaag cccttcacgt
      661 gcgcgcccac cgccgacacg cggccgacga tctcgtggcc gggcacgcag gggtagagcg
      721 tgcccggcca ctccgagcgc acctggtgga ggtcggagtg gcatacgccg cagaaggcga
      781 tttcgatctg cacgtcgtgc ggccccggcg cgcgccgggt gatctccatg gcttcaaggg
      841 gcaggtcgcc ggcacgggcg ccgtaggctt tgacggtcat cgggcgtttc tcgggttgga
      901 tggagggatg ataaccagag aagccgtccc ggcccgcgcg tttgtcccca gccggtgggg
      961 aaaggcatgt gggcgagcct gtggacaatc gcgcgcaggc cgcaggaagc aaggcttctg
     1021 ggtacctgcc tcattctgag gcagacgagc cccgtggcgt tcccgatcac cggattcgcg
     1081 gctgccgccg ctcctacagt gtcggttcgt gtcgggcgtc gaggtgcggg aaacgcgcgg
     1141 ggtgcgcgcc ggttcatgta ggagcgccgg caggcgcgaa agcggggatc gggattgcgg
     1201 agcgtgtcgg tcgccggatc gccgaattcg cggctgccgc cgctcctaca agggcatatc
     1261 ggttcgtgtc gggcgtcgag gtgcgggaag gccagggcgt ggcggttcgt gtcgggcgtc
     1321 gaggggtggg aacgcgcggg ggtgcgcgcc ggttcatgca ggagtgccgg caggcgcgag
     1381 cggggtgtct cggctacgtc gccgcaggcc ggccgacgct gtagtagtgc cagccggccg
     1441 cgcgcaggcg ctcggggttg tagaggttgc gcccatcggc gatcaccttg gtctggagca
     1501 gcgtcgccat ctcgtcgaaa tccggcgcgc ggaactgctg ccactcggtg caaatcgcca
     1561 gcgcgtccgc gccctcgagc acgctgtact tgtggctcgc cagcgccagg tcggcgcgcg
     1621 ggccgtagat ccgccgtgtc tcgtccatcg ccaccgggtc gtaggcctgt acgcgggcgc
     1681 cgtgctgcca cagtgcctcg atcaggctgc ggctgggggc ctcgcgcagg tcgtcggtgt
     1741 tgggcttgaa ggcgaggccc cacaccgcga ccgtgcgtcc ggcgagcccg tcggggccac
     1801 cgaagtggtg ggcgagcttg gcaaacaagg tgttcttctg gcgctggttc accgtctcca
     1861 ccgcccgtag cagcggcgcg tcgtagccca cctggtcggc gatgcggccg agcgcctgga
     1921 cgtccttcgg gaagcatgag ccgccgtagc cgcaaccggg gtagatgaag tgatagccga
     1981 tgcgcgggtc cgcgccgatg cccttgcgca cctcctcgat gtcggcgtcg aggcgctcgg
     2041 cgaggttggc gagctcgttc atgaggctga tgcgggtggc gagcatggcg ttggcggcgt
     2101 acttggtgag ctcggcgctg cgcacgtcgg tgaacagcgt gcgctcgtga ttgcggttga
     2161 agggctcgta gatctcgcgc atacgctcct gggcgcgcgc cgagcgcgtg ccgacgagga
     2221 tgcggtcggg cttcaggaag tcggcgaccg ccgcgccttc cttgaggaat tcggggttgg
     2281 agacgacgtc gaaggcgatc gtctcgccgc gcgcggcgag gatctgcgcg atgcgttcgg
     2341 ccaccttttc agcggtgccg accggcacgg tggatttgtt cacgatgacc cggtaggccg
     2401 gcatgtggcg ggcgatctcc tcggcgaccg cgagcacgta ctgcaggtcg gccgagccgt
     2461 cctcgtcggg cggggtgccg acggcgatga actgcacctc cgcgtgctgc accgcctcgg
     2521 ccgtgtcggt ggtgaagcgc agccgacctt cggcgaggtt gcgctcgacg atcggctgca
     2581 ggccgggctc ccagatgggg atggtgccgg cgcggagccg gtcgatcttg gcctggtcga
     2641 cgtccatgca cagcacgtcg tggccgacct cggccaggca ggcgccgctg accaggccga
     2701 cgtagccggt accgaaaatg ctgagcttca tgaggtgaac ccctgtgtgc gcgaatgcgc
     2761 cagacgctag ggagtccggg tgaagcggtc gtgaagcttg cgtgaaggga aggttgcgaa
     2821 gtgctccggc tcatgtagga gcgccgccag gcgcgaaggc ggcggtggag attgcggagc
     2881 gcgtcggtcg ccggatcgcc ggattcgcgg ctgccgccgc tcctacaggg gccgtggttc
     2941 gtgtcgggtg tcgatgggcg ggaaggccgg ggcgtggagg ttcgtctcgg gcgtcggtgg
     3001 tgggaaacgc gtcgggcgcg cgttggttca tgtaggagcg ccggcaggcg cgaaaggggt
     3061 ggagattgcg gagcgcgtcg gtcgccggat cgccggattc gcggctgccg ccnnnnnnnn
     3121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnccggcagg cgcgaaaggg gtggagattg
     3241 cggagcgcgt cggtcgccgg atcgccgaat tcgcggctgc cgccgctcct acaggggcgt
     3301 gtcggttcga gtcgggcgtc ggaggggagg gccggggcgt ggtggttcgt gtggggcgtc
     3361 gaggggcagg aagcccccgg gtgcgcgccg gttcaggtag gagcgccggc aggcgcgaag
     3421 gcggcggtcg ggagggaccg cgcttcggtt cccgaccgca ggaattcgcg cctgccgccg
     3481 cgcctgcgga tcagttctgg acggcttcga gcgacacggt gatggtcacc tcgtcgccga
     3541 cgttgggggc gtatttgccg gcgttgaact cgctgcgctt gatcacggtg ctggcgttgg
     3601 cgccgatggc gtccttcttg agcatcgggt gcggcatggt ggcgaagtgg ttcaccttca
     3661 gcgtcaccgg cttggtcacg cccttgatgg tcagctcgcc gtcgatggtc gcgggcttgt
     3721 caccgtcgaa gctcaccttg gtcgacttga aggtggcggt ggggtacttg gcggtgtcga
     3781 ggaagtcctc gccctggatg tgctcgtcga aggcggcgta gccggtgctc accgacttca
     3841 tgtcgatggt gacctccacc gcgccggtct tcgcttcctt gtcgagcgtg acggtgccgg
     3901 tggtcttgtc gaacttcgac atctggatcg acatgccgaa gtggctgtag gagaagctcg
     3961 ggaaggtgtg ggtgctgtcg accacgtagg tctggggcgc agccagcgcg ggcgaggcgg
     4021 cagcggcgga gaccaggagg gcggcggtca ggcgggtgat acggttcatg tggagtcctc
     4081 tgtgacgttg gggggatgaa gggcagggtg cggtagatca agggtgggaa gacggtggtc
     4141 gaggcaatcg gctgcgcagg cttgccgccc ggcacgagcg gctgccccgg ttcagcgcgc
     4201 cgcggcggtg atgctgaagc ggatcacgac gtcgttggcg accacgtcga aggccttcca
     4261 ggcgccttcg ccgatcgaga agtcgccgcg ccggatggtc agcgcgccct cgaagacgcc
     4321 gccgccgccc tgcacggtga aggtggcggg gaccacgacg tcccgggtcg tgcccttgat
     4381 ggtgagcttg ccggcgacct cgtacttgtc gccgccgagc ggcttcaccg cgctcgactc
     4441 gaagcgcgcg accgggaagc ccttggtgtc gaaccaggtc ttgcgggcga cctcctcgtc
     4501 gccttcctcg ctgccggtgt cgacgctggc gagatcgact tcgatgcgag ccgaggcaga
     4561 ctgcggtgcg gcggggtcga agcgcagctc gctgacgaac ttgccgaacg tgccctgcat
     4621 cgccacgccc atctgctggt agtcgaaggc gatgcggctc ttgtcgggct ggaccttgcc
     4681 gtactccacc gcgtgagcag cggtggcggc gaaggcgaag gaggcgagga gggcgagggc
     4741 gatgcgtttc atggcgagaa atcctgtatg cgatgggtga cggcggccgg ttcagccttt
     4801 gcggcgcggc agcatgcgga tcagcacgtc gtcgcggtcg atgaagtgat gcttgagcgc
     4861 ggcgccgacg tggccgagca gcacggcgat cagcgtgtag ttcagaacga aatgcaccgt
     4921 ctcgagcagg ttgccgagcg ccttgtcctt ggcgagcagg tcgggcagcg gcagcacgcc
     4981 gaaccacacc gtctggaagc ccttcgccga gctcatcagc cagccgctga gcggaatcgc
     5041 gagcatcagc acgtagagca ggtgatggcc cgcgtgcgcg gccaggcgct cgatggccgg
     5101 catgtgcgcg ggcagtgccg ggggcttgtg gccgatccgc caggccaggc gcaccagtac
     5161 gagcacgaac accgtcacgc ccgcccactt gtgccaggag taaagctcca gcttggtggg
     5221 cgacaggtcc agcccggtca tgtagaagcc gaagccgagc atgccgaaga tcatcagcgc
     5281 gatgagccag tgcagcagct tggcggtggc ggtgtagtga gtgtccatcg cggttcgtcc
     5341 ttcggccttc gatcgcgagc gccggcctcg tgttcgtgtt gattgcactc tagacgcatt
     5401 cagacggctt aaacagccaa ggatgggcaa aggttcgttg ctcttttcgc aacaaatggg
     5461 tttggatcgg ggtggttcag gcgcgctcgt tgcgcgattc gagccttcca caggcgccct
     5521 agcccacgcc ggggatgtcg ttgccgtgac gcgcgagcca gaccacgatg cgcggcaggt
     5581 ccggggcgca ctccgcatac tgggcagggc acaggtcggt gaggacccgc tcgggcatac
     5641 ggcagtcggc caccggctcg ctcaccagcg tgtcgagatc ggcgggcagc gcgaggcagg
     5701 ccgggaggag aagcgctgga tgcggggggc gatacgggaa acggtggagc gcgtgttggg
     5761 cgggcccgtg ggggcggatg ccagcagtcg agcctgaagg cttgcttttg cccgcgtaga
     5821 gcgaactgga aaagggggcg cagcccagtg gcgatcgata cctgagtggc tcggatcgaa
     5881 gcggccgggc gcagccccgt cctccacccg gctcggccgc gacggttgat gcacgagcgc
     5941 ggcagggcgc gaatgcagcc atgcgccgac gccttcagcc caggcttctg cgcagccggc
     6001 cgatgtcggg gatgtggatg gtgcggccct cgacgtggat gagtccggcg ccggtgagct
     6061 cgttcaggat gcgcgagaag tgttcctggg tgaggttcag gcgcgaggcg atggtgccct
     6121 tgctggtggg caggcgcagc gacaccgcgc cttcggagac gccgtcgcct tcgcgctcct
     6181 cctcgcgcag caggtagccg accacgcggt cgcggcccga gcgcagcgag tagctctcga
     6241 cgtcggccat cagcaggtgc aggcgctggg cgaggccggc gatgatcttg cggcagaaca
     6301 ccggatcgcc cgacatctcc tcgaagaaga tctgcttgcc gatatgcagc agggtcgcgt
     6361 cggtgagcgc ctgcgccatc acgacgtagg gcttgtccat gaacatcacc gcctcgccga
     6421 agctgcgtcc ggcgtagagg atgtccacca ccttctcgtt gccctcggcc gaggtgaagg
     6481 cgagcttgat ctggccgtcg aggatgaggt ggaagccgtg gcaggggtcg ccacggtgga
     6541 agaggatctc gccgcgcgcg acgcggacct cgcgcacgcc gcgcgcgaag cggacgatgt
     6601 cctcgcaggc gagcccgttg aacagcgagg cgcgcgcgag cagacggcac agccgctcga
     6661 gctcggtgac cgggctgccc gtggagggat cgatgtggaa gggtcgttcg ccgaccgggg
     6721 tggcgctacg gggcatggct tcagcgggtg agctgggcgt agaacatggg cagccgggcg
     6781 ggcagctcgt cgggctggcg gatcaccgcg tagccggccg gaccgaagag atgcggcagg
     6841 tagctcgcgc cctcgcggtc gatggtaacg cagaacggaa ccacgccgcg gttgcgcgcc
     6901 tcgaccacgg cgacgcgggt gtcctcgatg ccgtagcggc cgtcgtagag gtcgagatcg
     6961 ttgggcttgc cgtcggacag gatcagcagg attcggcgcg cggcgcgctg gcggtcgagg
     7021 atcgtggtgg cgtggcggat cgccgcgccc aggcgggtgt agtagcccgg cttgatcgcc
//
LOCUS       DAOTIN010000156         6829 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_13222_length_6829_cov_9.716711, whole genome shotgun sequence.
ACCESSION   DAOTIN010000156 DAOTIN010000000
VERSION     DAOTIN010000156.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 6829)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 6829)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6829
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_13222_length_6829_cov_9.716711"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..946)
                     /locus_tag="P5537_15405"
     CDS             complement(<1..946)
                     /locus_tag="P5537_15405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3382 domain-containing protein"
                     /protein_id="HRV79474.1"
                     /translation="MSAVVFARHAMTPAERLRDAGWVAFVGLILGIPLVGLTTVDVGG
                     RLGVETRFGLLAAAVAAVFAGRLLLRWAIDQARNRKQERDRASTATAADRAHGAQRVV
                     NVLGWVALGASIALPILFSDNRYVVDTATTVLIYVMLGWGLNVVVGLAGLLDLGYVAF
                     YAVGAYSYALLSTQFGWSFWEALPVSGAMAATFGILLGYPILRLRGDYLAIVTLGFGE
                     IIRIILVNWTEFSGGPNGISSIPRPSFFGLDFTRSAPEGSQTFAGFFGLEFSPMHRLI
                     FLYYLILVLALLTHAFVSRLRKLPVGRAWEALREDEIAC"
     gene            complement(946..1860)
                     /locus_tag="P5537_15410"
     CDS             complement(946..1860)
                     /locus_tag="P5537_15410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002931192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HRV79475.1"
                     /translation="MAYALQQLINGLTLGAMYGLIAIGYTMVYGIIGMINFAHGDIFM
                     VSAFIAVTAFTILAAADVTSIPLALTFVLIVSIFFTSAYGWAVERTAYRPLRGSTRLA
                     PLISAIGMSIFLQNSVQLTQGARVKPIPPVLEGGIVLWDAPGFTVQIGWSQMLIIVTT
                     VILMTAFTWMITQTPFGRQQRACEQDRTMASLLGVNVDRTISFTFMLGAALAAVAGVM
                     VTVYYGVVDFFIGFLAGIKAFTAAVLGGIGSLPGAMLGGLLIGLIESFWAAYLWAEYK
                     DVATFGILCLVLMLRPSGLLGRPEVEKV"
     assembly_gap    2000..2099
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(2117..3211)
                     /locus_tag="P5537_15415"
     CDS             complement(2117..3211)
                     /locus_tag="P5537_15415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004291283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     substrate-binding protein"
                     /protein_id="HRV79476.1"
                     /translation="MKKTLLATTVLALGGFSTAAMADLAVAIAGPMTGQYASAGDQIR
                     KGAEMAIADINARGGVLGEKLKLEIGDDACDPKQAVSVANTMVNKGIVFMHGHWCSSS
                     TIPASEVYVEADIPMATVSTNPQVTERGLKNIFRIMGRDDQQGLVAGSYIAEKFAGKK
                     VAVVDDKSAYGKGLADEMAKAMEGKGLKPTLRESITAGEKDYSGIVTKLKQAGVEVMA
                     YGGYHTEVALILRQAQAAGLQLTVMGGDTMTNSELVTAAGPAADNVMFTFSPDPRKNP
                     DAAPVVEKFRAAKTEPEGYVLYAYAAMQLFEQAATTAKSTKYADLEKAMRGGSFKTVI
                     GELAFDAKGDQKAPGFVVYRWQGGKYDYAK"
     gene            complement(3392..>6829)
                     /gene="putA"
                     /locus_tag="P5537_15420"
     CDS             complement(3392..>6829)
                     /gene="putA"
                     /locus_tag="P5537_15420"
                     /EC_number="1.2.1.88"
                     /EC_number="1.5.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0003842 - 1-pyrroline-5-carboxylate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0004657 - proline dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0010133 - proline catabolic process to
                     glutamate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional proline dehydrogenase/L-glutamate
                     gamma-semialdehyde dehydrogenase PutA"
                     /protein_id="HRV79477.1"
                     /translation="GVALMCLAEALLRVPDKATADRLIRDKLADGDWRAHIGNSPSLF
                     VNAATWGLLITGRLVSTSSEQGLSSALTRLVARGGEPLIRKGMDLAMRMLGEQFVTGR
                     DIDEALERGREHEKKGYRYSFDMLGEAAMTAADAERYFKDYERAIEAIGTASKGRGVV
                     DGNGISVKLSALHPRYTWSQRERVLAELLPKLKTLCLQARRHDIGLNIDAEEADRLDL
                     SLDLLEALALDDALAGWTGLGFVVQAYQKRAPYVLDFVIDLARRSGQRMMVRLVKGAY
                     WDAEIKRAQIDGLAGYPVYTRKVYTDVSYLACAKKLLAARDAIYPQFATHNAHSLAAI
                     FHLAAADGRAWQPGDYEFQCLHGMGEPLYDQIVGRADRHRLVRIYAPVGSHETLLAYL
                     VRRLLENGANTSFVNRIVDERVPVEELIADPVEQAAPLAGAPHPRIALPAELFGAQRI
                     NSAGIDLASEPVRARIAAALAGSRATPFAAGPVVAGRSAVPADVAPVSNPADRGEVVG
                     GVAEATTDDIEHALTASSAAAADWAATPAALRCDCLERAAALFEREADTLLALAVREA
                     GKSWANAVAELREAVDFLRYYAQQARGFDAASHVPLGPVLCISPWNFPLAIFSGQVAA
                     ALAAGNPVLAKPAEQTPLIAAFAVRLLHEAGIPAAVLQLLPGRGETVGAALVADARVR
                     GVMFTGSTEVAALINRKLAERGGNVPLIAETGGQNAMIVDSTALPEQVVGDVLASAFD
                     SAGQRCSALRVLCLQQDIADGVLHMLQGALAELRLGNPADVRVDIGPVIDSEARAGLE
                     AHVAAMQARGGRVTRLPLPAECAHGTFVAPTLIEIGALSELGREQFGPILHVLRYRAS
                     ELDELIDAINASGYGLTMGVHTRIDETVERVAARAHVGNLYVNRNIIGAVVGVQPFGG
                     EGLSGTGPKAGGPLYLHRLLARTPGPVLADGAVSVSEGDETRAADAALADFLAWLDGA
                     GRGLVEGDEFAVLRDRADACRARRLAGLRVALPGPTGEDDGLRFSARGTIAGVAEGTA
                     AVLLQVMAALASGNQLLLADGEAARKVQAALPDALRSHVRVDANWFDRALGAVLFDGS
                     ETEADALRVRVAARTGPILQLLRPTPDYDLSRLAHERTLSINTAAAGGNASLMAMGA"
BASE COUNT          989 a         2249 c         2511 g          980 t
ORIGIN      
        1 ggcaggcgat ctcgtcctcg cgcagcgcct cccaggcgcg gcccaccggc agcttgcgca
       61 ggcgcgacac gaaggcgtgg gtgagcaggg ccagcaccag gatcaggtag tagaggaaga
      121 tcagccggtg catcggcgag aactccagcc cgaagaagcc ggcgaaggtc tggctgcctt
      181 ccggcgcgct gcgggtgaag tcgaggccga agaagctcgg gcgcgggatc gagctgatgc
      241 cgttgggccc gccggagaac tcggtccagt tcaccaggat gatgcggatg atctcgccga
      301 agccgagcgt gacgatggcg aggtagtcgc cgcgcaggcg caggatcggg tagccgagca
      361 ggatgccgaa ggtcgccgcc atcgcgcccg agaccggcag tgcctcccag aagctccagc
      421 cgaactgggt cgacagcagc gcgtaggagt aggcgcccac cgcgtagaag gcgacgtagc
      481 cgaggtccag cagaccggcg aggccgacca cgacgttgag gccccatccg agcatcacgt
      541 agatcagcac cgtggtggcg gtgtcgacca cgtagcggtt gtcggagaac aggatcggca
      601 gcgcgatcga ggcgccgagc gcgacccagc cgagcacgtt caccacgcgc tgtgcgccat
      661 gggcacggtc ggcggcggtg gcagtgctgg cacggtcgcg ctcctgcttg cggttgcgcg
      721 cctggtcgat cgcccagcgc agcagcaggc ggcctgcgaa taccgcggcg acggccgcgg
      781 cgagcaggcc gaagcgggtc tccaccccca gccggccgcc cacgtccacc gtggtgaggc
      841 cgaccagcgg gatacccagg atgaggccga cgaaggccac ccagccggcg tcgcgcaggc
      901 gctcggcagg cgtcatcgcg tgacgcgcaa agacgacggc gctcatcaga ccttctccac
      961 ttcaggccgg ccgagcaggc cggaggggcg cagcatcagc accaggcaca ggatgccgaa
     1021 ggtggcgacg tccttgtatt cggcccacag gtaggcggcc cagaaggact cgatgaggcc
     1081 gatcagcagg ccgccgagca tggcccccgg cagcgagccg atgccgccca gcaccgccgc
     1141 ggtgaaggcc ttgatgccgg cgaggaagcc gatgaagaaa tcgaccacgc cgtagtacac
     1201 cgtgaccatc accccggcca ccgcggccag cgccgcgccg agcatgaagg tgaaggagat
     1261 cgtgcgatcc acattgaccc cgagcagcga ggccatggtg cggtcctgct cgcaggcgcg
     1321 ctgctggcga ccgaaggggg tctgcgtgat catccaggtg aaggctgtca tcaggatcac
     1381 cgtggtgacg atgatcagca tctggctcca gccgatctgc accgtgaagc ccggcgcgtc
     1441 ccaaagcacg atgccgcctt ccagcaccgg cgggatgggc ttcacgcgcg cgccctgggt
     1501 gagttgcacg ctgttctgca ggaagatcga catgccgatc gccgagatca gcggcgccag
     1561 ccgggtcgag ccgcgcagcg ggcggtaggc ggtgcgctcg accgcccagc cataggccga
     1621 ggtgaagaag atcgacacga tcagcacgaa ggtcagcgcg agcgggatcg aggtgacgtc
     1681 ggcggcggcg aggatcgtga aggcagtgac cgcgatgaac gcgctcacca tgaagatgtc
     1741 gccatgggcg aagttgatca tgccgatgat gccgtacacc atcgtgtagc cgatggcgat
     1801 caggccgtac atggcgccga gcgtgagccc gttgatcagt tgctggagtg cataggccac
     1861 gatgtctcct gctgtggcgg tgcggatggc gcggaccccg caagggggcc gtgccctgta
     1921 ggagcggcgg aagccgcgat caggcgctgg atcacgcgcg gtcgctcgcg gatggcccgc
     1981 tcgcgtcgcc ctctcggcgn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnc
     2101 cggacgagcg cgcggcttac ttcgcgtagt cgtacttgcc gccttgccag cgatagacca
     2161 cgaagcccgg cgccttctgg tcgcccttgg cgtcgaaggc cagctcgccg atcacggtct
     2221 tgaagctgcc gccgcgcatc gccttctcga ggtcggcgta cttggtgctc ttggccgtgg
     2281 tcgcggcctg ctcgaagagc tgcatcgcgg cgtacgcata cagcacgtag ccttccggct
     2341 cggtcttggc ggcgcggaac ttctccacca ccggggcagc gtccgggttc ttgcgcgggt
     2401 cgggcgagaa cgtgaacatc acgttgtcgg cggcggggcc ggcggcggtg acgagctcgg
     2461 agttggtcat ggtgtcgccg cccatcacgg tgagctggag gccggcggcc tgggcctggc
     2521 gcaggatcag cgcgacctcg gtgtggtagc cgccgtaggc catgacctcg acgccggcct
     2581 gcttgagctt ggtgacgatg ccggagtagt ccttctcgcc ggcggtgatg gattcgcgca
     2641 gcgtgggctt gagacccttg ccttccatcg ccttggccat ctcgtcggcg aggcccttgc
     2701 cgtaggcgct cttgtcgtcg accacggcga ccttcttgcc ggcgaacttc tcggcgatgt
     2761 agctgcccgc gaccaggccc tgctggtcgt cgcggcccat gatgcggaag atgttcttga
     2821 gtccgcgctc ggtcacctgc gggttggtcg acacggtggc catcgggatg tcggcctcga
     2881 catagacctc ggaggcgggg atggtcgagc tcgagcacca gtggccgtgc atgaacacga
     2941 tgcccttgtt gaccatggtg ttggccaccg acaccgcctg cttcgggtcg caggcgtcgt
     3001 cgccgatctc gagctttagc ttctcgccga ggacaccgcc gcgggcgttg atgtcggcga
     3061 tggccatctc cgcgcccttg cggatctggt cgccggcgga ggcgtactgg ccggtcatcg
     3121 ggccggcgat ggcgaccgcg aggtcggcca tggctgcagt cgaaaagccg ccgagcgcga
     3181 ggacggtggt ggcgagcagg gtttttttca tgaaacgtct ccttcgtggc tgtggttttg
     3241 tgccttggac ggggcattcg gcgccggagg gtgccgcttg cgtccggcaa aggtaagcga
     3301 atttttcgtt cttgccatcc gtgatgcccc tagctggtga ttccagcccg gatcggggct
     3361 cgtccgggct gttttcggtc acggtaccgg cctatgcacc catcgccatc aggctggcgt
     3421 tgccgccggc ggcggcggtg ttgatcgaca gcgtgcgttc atgggcgaga cggctcaggt
     3481 cgtagtcggg cgtcggccgc agcagctgca ggatcgggcc cgtgcgtgcc gcgacgcgca
     3541 cgcgcagcgc gtcggcctcg gtttcgctgc cgtcgaacag taccgcgccg agtgcccggt
     3601 cgaaccagtt cgcatccacc cggacatgac tgcgcagggc atccggcagg gccgcctgca
     3661 ccttgcgcgc agcctcgccg tcggcgagca gcagctggtt gccgctggcg agcgccgcca
     3721 tcacctggag gagaacggcg gcggtgccct ccgccacgcc ggcgatggtg ccgcgcgcgc
     3781 tgaagcgcag gccgtcatcc tcgccggtag ggccggggag tgccacgcgc aggccggcga
     3841 ggcggcgcgc gcggcaggcg tcggcgcggt cgcgcagcac ggcgaactcg tcgccctcca
     3901 ccaggccgcg gccggcgccg tcgagccacg cgaggaagtc ggccagcgcg gcatcggcgg
     3961 cgcgggtctc atcgccctcg ctcaccgaga ccgcgccgtc ggccagtacc ggccccggcg
     4021 tgcgcgccag caggcggtgc aggtagagcg gcccgcccgc cttcggcccg gtgcccgaca
     4081 ggccctcgcc gccgaagggc tgcacgccga ccacagcgcc gatgatgttg cggttcacat
     4141 acaggttgcc gacgtgagcg cgcgcggcga cgcgctcgac ggtctcgtcg atgcgggtat
     4201 gcacccccat ggtgaggccg tagccgctgg cgttgatggc gtcgatcagc tcgtcgagct
     4261 cggacgcgcg gtagcgcagc acgtgcagga tggggccgaa ctgctcgcgg ccgagctcgg
     4321 agagcgcacc gatctcgatg agggtcggcg cgacgaaggt gccgtgcgcg cactcggcgg
     4381 gcagcggcag gcgggtgacg cgcccccccc tggcctgcat cgcggcgaca tgggcctcca
     4441 gcccggcgcg ggcctcggaa tcgatcaccg ggccgatgtc cacgcgcacg tcggcggggt
     4501 tgcccaggcg cagctcggcg agcgcgccct gcagcatgtg cagcacgccg tcggcgatgt
     4561 cctgctgcag gcacagcacg cgcagcgccg agcagcgctg gccggcggag tcgaaggcgg
     4621 aggcgagcac gtcgccgacc acctgctcgg gcagcgcggt ggagtccacg atcatcgcgt
     4681 tctggccgcc ggtctcggcg atcagcggca cgttgccgcc gcgctcggcg agcttgcggt
     4741 tgatcagcgc ggcgacctcg gtggagccgg tgaacatcac cccgcgcacg cgcgcatcgg
     4801 ccaccagcgc ggcgccgacg gtctcgccgc ggccgggcag cagctgcagc accgcggccg
     4861 ggatgccggc ctcgtgcagc aggcgcaccg cgaaggcggc gatcagcggg gtctgctcgg
     4921 ccggcttggc gagcaccggg ttgccggcgg cgagcgcggc ggcgacctgg ccactgaaga
     4981 tggcgagcgg gaaattccac gggctgatgc acagcaccgg gccgagcggc acgtggctgg
     5041 cggcatcgaa gccacgcgcc tgctgggcgt agtagcgcag gaagtcgacc gcctcgcgca
     5101 gctcggccac cgcgttggcc cacgacttgc cggcctcgcg cacggcgagc gcgagcaggg
     5161 tgtcggcctc gcgctcgaac agcgccgcgg cgcgctccag gcaatcgcag cgcagcgcgg
     5221 ccggggtggc ggcccagtcg gccgcggccg cgctggaggc ggtgagcgca tgctcgatgt
     5281 cgtcggtcgt cgcctcggcg acgccaccga cgacttcgcc gcgatcggcc gggttggaga
     5341 ccggcgccac gtctgccggc accgcgctgc ggccggccac gaccgggccg gcggcgaagg
     5401 gcgtggcgcg cgaaccggcc agcgcggcgg cgatgcgtgc gcgcaccggt tcgctggcga
     5461 gatcgatgcc ggccgagttg atgcgctgcg cgccgaacag ctcggccggc agcgcgatcc
     5521 tgggatgcgg tgcgccggcg agcggggcgg cctgctcgac cgggtcggcg atcagctcct
     5581 ccaccggcac gcgctcgtcg acgatgcggt tcacgaagct ggtgttggcg ccgttctcga
     5641 gcaggcggcg caccaggtag gcgagcaggg tctcgtggct gcccaccggg gcgtagatgc
     5701 gcaccaggcg gtggcggtcg gcgcggccga cgatctggtc gtagagcggc tcgcccatgc
     5761 cgtgcaggca ctggaactcg tagtcgcccg gctgccaggc gcggccgtcg gcggcggcga
     5821 ggtggaagat cgccgccagc gagtgcgcgt tgtgggtggc gaactgcggg tagatggcgt
     5881 cgcgcgcggc gagcagcttc ttcgcgcagg cgaggtagga gacgtcggtg tacaccttgc
     5941 gcgtatacac cgggtagccg gccagcccgt cgatctgcgc gcgcttgatc tcggcgtccc
     6001 agtaggcgcc cttgaccagg cgcaccatca tgcgctgccc gctgcggcgg gcgaggtcga
     6061 tgacgaagtc gagcacgtag ggggcgcgct tctggtaggc ctgcaccacg aagcccaggc
     6121 cggtccagcc ggcgagtgcg tcgtcgagcg cgagcgcctc gagcaggtcg agcgagaggt
     6181 cgaggcggtc ggcctcctcg gcgtcgatgt tgaggccgat gtcgtggcgc ctggcctgca
     6241 ggcacagggt cttcagcttc ggcagcagct cggcgagcac gcgctcgcgc tgcgaccagg
     6301 tgtagcgcgg gtgcagggcg gagagcttca ccgagatgcc gttgccgtcg accacgccgc
     6361 ggcccttcga ggccgtgccg atggcctcga tcgcgcgttc gtaatccttg aagtagcgct
     6421 cggcgtcggc ggcggtcatc gcggcctcgc cgagcatgtc gaaggagtag cggtagccct
     6481 tcttctcgtg ctcgcggccg cgctcgaggg cctcgtcgat gtcgcggccg gtgacgaact
     6541 gctcgccgag catgcgcatc gccaggtcca tgcccttgcg gatcagcggc tcgccgccgc
     6601 gcgccaccag ccgggtgagg gcggacgaca ggccttgttc gctgctggtc gacaccagcc
     6661 ggccggtgat cagcaggccc caggtcgcgg cgttgacgaa cagcgagggg ctgttgccga
     6721 tgtgcgcgcg ccagtcgccg tcggcgagct tgtcgcggat caggcggtcg gcggtggcct
     6781 tgtcgggcac gcgcagcagc gcctcggcca ggcacatcag cgccacgcc
//
LOCUS       DAOTIN010000157         6816 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_13249_length_6816_cov_9.422127, whole genome shotgun sequence.
ACCESSION   DAOTIN010000157 DAOTIN010000000
VERSION     DAOTIN010000157.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 6816)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 6816)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6816
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_13249_length_6816_cov_9.422127"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..181
                     /locus_tag="P5537_15425"
     CDS             <1..181
                     /locus_tag="P5537_15425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004383512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HRV79478.1"
                     /translation="IPFLVSRSGLTHMGWQIAQKIGLTMIGRAQGKHYLLFSGADRFE
                     RDCSAPTHEDETTPR"
     gene            178..804
                     /gene="mobA"
                     /locus_tag="P5537_15430"
     CDS             178..804
                     /gene="mobA"
                     /locus_tag="P5537_15430"
                     /EC_number="2.7.7.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004383514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0061603 - molybdenum cofactor
                     guanylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase MobA"
                     /protein_id="HRV79479.1"
                     /translation="MNPTTSPRPADRRITGVLLAGGQGSRMGGVDKGLVELAGRPMAA
                     HALARLAPQVDELIINANQNPSAWQAFGHPVFGDDIGGFAGPLAGLHAALVRARHPLV
                     VTAPCDSPFLPADLVERLATALHAAGAQLAVAKTFDQPHPVFCLCRRDLAEHLGTFLA
                     GGGRKIDRWYGSLKVVEVAFDDEEAAFRNINTRDELAAAAKDLPAGAA"
     gene            949..1857
                     /locus_tag="P5537_15435"
     CDS             949..1857
                     /locus_tag="P5537_15435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015433722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HRV79480.1"
                     /translation="MAERTPAGLPGPCLDTREAAAFLHLNEKKLYELAKNGELPAARV
                     GGKWLFPRALLEEWLLEQAHGGALSDRLLITGSDDPLLSATVAALAPALGAEAFVAYS
                     PTGTLAGLELLARRRANVCALHWGGVEHSVQQHAMLLRRFGPHRKWALVRLALREQGV
                     ILRRGLQVDGIETLAAFDYRWAMRQPGAGSAHFLESALAGRGFSAADCSAVATAHSER
                     EAAAVVAREDADCAPGTRAAATEFGLGFLPLGWEAFDLALPREILFRRLFQDLLSACA
                     SPSARALAQRLGGYDLAPLGKIIGLD"
     gene            complement(2164..2679)
                     /gene="mobB"
                     /locus_tag="P5537_15440"
     CDS             complement(2164..2679)
                     /gene="mobB"
                     /locus_tag="P5537_15440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004384485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HRV79481.1"
                     /translation="MKVMGFAGWSGSGKTTLVEQVIAALSARGLVVSLVKHAHHSFDI
                     DHAGKDSWRHRRAGCREVMVSSDQRWSLTRELRGAPEAGLDELLGHLGPCDLVLVEGF
                     KRAAIPKIEVWRSVVGEPLLHPHDPWIVALATDMPVESALPRLDINDPEAVADFIVEH
                     LGLRTGARSAR"
     gene            complement(2676..4757)
                     /locus_tag="P5537_15445"
     CDS             complement(2676..4757)
                     /locus_tag="P5537_15445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cache domain-containing protein"
                     /protein_id="HRV79482.1"
                     /translation="MSLAERLRGSVRAKLLALVLAPLMLGFPLIMGLLWYWGEVYYHR
                     LMVSRVASDLATAHGYFERVIDGVGSRVQALAGSHALAQSLAHETPEAVAALLGARKG
                     GLALDFLNLLDVNGRVLHSSTAMAAGSARGDWSVVQRAIGARGGSVVERFAAAELAAI
                     DVGLRERARLALVATPRARPDPRPEEERGLVVHAAAPVLDAAGNLVAVLEGGVLLNGN
                     LDFVDTLNAIVYREGSLPEGSEGTATLFVDDVRIATNVRLFEGARALGTRASDEVRAH
                     VLDHGRTWLETAFVVNDWYVSAYEPVMDSRGERVGMLYVGFLEAPFRAAKRTALLVVG
                     ALALLVSAAGALLTLFWARGIFRPIERMHATIGRIDAGDEHARVGDVASRDELGRLAT
                     AFDHLLEEQAARRAELQALNASLDRKVAERTADLAAANEELRAAQHRLVMSEKLAAIG
                     ELTAGVAHEISNPTAVIQGNLDLLREELGPAAQPVANEIRLIHEQVGRIRLIVTKLLQ
                     FARPDEFAGYVEDVDVNAALADCLVLTRQHLARAEVKVVQRLGASGRVQINLQELQQV
                     LINLIVNAVQAMPAGGTLTLETVDRDPVRDARGVRITVRDTGGGIRAEDLARIFDPFF
                     TTKKRQGTGLGLSISHTLVERYGGRIEVDSAPGEGAAFTVSLLAEPVYRKDPAPPPGG
                     REDGTGQTEAT"
     gene            complement(4822..6297)
                     /locus_tag="P5537_15450"
     CDS             complement(4822..6297)
                     /locus_tag="P5537_15450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004384776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HRV79483.1"
                     /translation="MVAKPHGGDCGAAAAGAGAAPGEGIAPARPVELADYDWPAHSVL
                     VVDDEEGMRNFLERTLARRCGMVQSAADAEHAAALMARLHFDLLVLDIALPGKSGIEW
                     LHELREHGYAGDVILITAFADMETAIDALRGGASDFILKPFRVDQILNSIKRCFERAG
                     LARENFVLRRELAGLGAEPTGLIGHSPAMEQLRALVRRVGQMPSTVLLLGESGTGKEV
                     VARALHQTSPRAQRPFVPLNCAAIASELIESELFGHVKGAFTGASESRNGLFYYAHGG
                     TLFLDEISELPLAMQTRLLRVLEERKLRPVGSERELPVDVRIIAASNRDLAAEVRVGR
                     FREDLYYRLAVVDIALPPLRARAEDIPELMRHFMQQLAVQLGVPPLPLSHEVVSRLAG
                     YSWPGNVRELRNYVERSLILGCFPPQPSAAPTAAPTPAGELELSLAEVERRHIERVTA
                     ACEGNKTEAARRLGVSRKTLERKFAEWALEDAAATRAERRA"
     gene            complement(6300..6710)
                     /locus_tag="P5537_15455"
     CDS             complement(6300..6710)
                     /locus_tag="P5537_15455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopD family protein"
                     /protein_id="HRV79484.1"
                     /translation="MLTLKAFHIVFVVSWFAGLFYLPRLFVNHAMVEDAATRDRLAMM
                     EMKLYRFMTPLGILAVGLGLWLWFGYGFAGGWLHAKTLLVVFLIAYHLYCGRLMRAFA
                     EGRNTRSHVWYRYFNEIPVLVLFVVVFLVVLKPF"
BASE COUNT          964 a         2538 c         2405 g          909 t
ORIGIN      
        1 cattcccttc ctcgtctcgc gctccggcct cacccacatg ggctggcaga tcgcacagaa
       61 gatcggcctc accatgatcg gccgcgccca gggcaagcac tacctgctgt tttccggcgc
      121 ggaccgcttc gagcgcgact gcagcgcgcc cacacacgaa gacgagacca ccccacgatg
      181 aacccaacca cctccccccg ccccgccgac cgccgcatca ccggggtgct gctcgccggc
      241 ggccagggca gccgcatggg cggcgtggac aagggcctgg tcgagctcgc cgggcggccg
      301 atggcggcac acgcgctggc gcgcctcgcc ccccaggtcg acgagctgat catcaacgcc
      361 aaccagaacc cgtcggcgtg gcaggccttc ggtcatccgg tgttcggcga cgacatcggc
      421 ggcttcgccg gcccgctcgc cggcctgcac gcggcgctcg tgcgcgcccg ccacccgctc
      481 gtggtgaccg cgccctgcga ctcgcccttc ctccccgccg acctcgtcga gcgcctcgcc
      541 accgccttgc acgccgcagg cgcccagctc gcggtggcca agaccttcga ccagccgcat
      601 ccggtgttct gcctgtgccg gcgcgatctc gccgagcacc tcggcacctt cctcgccggc
      661 ggcggccgca agatcgaccg ctggtacggc agcctgaagg tggtcgaggt cgccttcgac
      721 gacgaggagg ccgccttccg caacatcaac acccgcgacg aactcgccgc ggcggcgaag
      781 gacctgccgg ccggcgccgc ctgagccggc gcgcgcacgc cgatgccggc ccgcaagaca
      841 ccgcccatct cgcctgcggc agcagcctgc cccgctgacc cgcacgacgc gtccatcccg
      901 cccggtgcgg aacatacgac gcccgcaagc ttcttcgcgg cacagggaat ggcggaacgg
      961 acgcccgccg gcctccccgg cccctgcctc gacacgcgcg aggcggccgc cttcctgcac
     1021 ctcaacgaga agaagctcta cgagctcgcc aagaacggcg agctccccgc cgcgcgcgtg
     1081 ggtggaaagt ggctgtttcc gcgcgccctg ctggaggagt ggctgctcga acaggcgcac
     1141 ggcggcgcac tcagcgaccg cctgctcatc accggcagcg acgatccgct gctgtcagcc
     1201 accgtggctg cgctcgcgcc ggcgctcggc gccgaggcct tcgtcgccta cagccccacc
     1261 gggaccctgg ccggactgga gctgctcgcc cgccgccgcg ccaacgtgtg cgccctgcac
     1321 tggggcggtg tcgagcacag cgtccagcag cacgccatgc tgctgcgccg cttcggcccg
     1381 caccgcaagt gggcgctggt gcgcctggcg ctgcgcgagc agggggtgat cctgcgccgc
     1441 ggcctgcagg tcgacggcat cgagacgctc gccgccttcg actaccgctg ggcgatgcgc
     1501 cagcccggcg cgggctcggc gcacttcctc gaatccgccc tcgccggccg cggcttctcc
     1561 gccgccgact gcagcgcggt cgcgaccgcc cacagcgagc gcgaggccgc cgccgtggtc
     1621 gcgcgcgagg acgccgactg cgcgcccggc acgcgcgccg cggccaccga gttcgggctg
     1681 ggcttcctgc ccctgggctg ggaggccttc gacctcgcgc tgccacgcga gatcctcttc
     1741 cgccgcctgt tccaggacct gctctccgcc tgcgccagcc cgtcggcccg cgccctcgcc
     1801 cagcgcctcg gcggctacga cctggcaccg ctgggcaaga tcatcggcct ggactgagcc
     1861 accgccgaag accgctcggg ggggcgcgat cggacgacgc cccggcgatg ggcgccgtcc
     1921 gcaacacgga ccgccgcttc gcgccggccg gcgcgaacgc ggtgagttcc cgtcacccgc
     1981 gtcgcctgcg gcacggccgt cttcgcggct gccgccgctc ctacggagac cgtcgccgct
     2041 gccgcggccc gtgccttggg ggcgcgtgat gtctcatgta ggagcgccgg caggcgcgaa
     2101 tgcagcgcgg gagcaggaac ccgggtcctt gccggaccac cccgtccgcg gctaccgccg
     2161 cgcctaccgg gcggagcggg cgccggtgcg cagcccgagg tgctcgacga tgaaatccgc
     2221 caccgcctcg ggatcgttga tgtcgagccg ggggagcgca ctctccacag gcatgtcggt
     2281 cgccaacgcg acgatccagg gatcgtgcgg atgcagcagg ggctcgccga ccacgctgcg
     2341 ccagacctcg atctttggaa tcgccgcgcg cttgaagccc tcgaccagca ccaggtcgca
     2401 cggcccgagg tggccgagca gctcgtcgag gccggcctcg ggcgcgccgc gcagctcgcg
     2461 cgtcagcgac cagcgctggt ccgagctcac catgacctcg cggcagccgg cccggcgatg
     2521 gcgccaggag tccttgccgg catggtcgat atcgaagctg tggtgggcgt gcttgaccag
     2581 cgacaccacc aggccgcgcg cgctcagcgc cgcgatcacc tgctcgacca gcgtcgtctt
     2641 gccgctgccg gaccagccgg cgaaacccat cactttcatg tcgcttccgt ttgtcctgtt
     2701 ccgtcttccc gtccgccggg cggcggcgcg ggatccttgc gatacaccgg ctcggcgagc
     2761 aggctcaccg tgaaggccgc gccctcgccg ggcgcgctgt ccacctcgat gcggccgccg
     2821 tagcgctcga ccagggtgtg gctgatcgac agccccaggc cggtgccctg gcgcttcttg
     2881 gtggtgaaga aggggtcgaa gatgcgcgcc aggtcctcgg cgcggatgcc gccgccggtg
     2941 tcgcgcacgg tgatgcgcac gccgcgtgca tcgcgcaccg ggtcgcggtc gaccgtttcc
     3001 agcgtcagcg tgccgccggc cggcatggcc tgcacggcat tgacgatgag gttgatcagc
     3061 acctgctgca gctcctgcag gttgatctgc acccggccgc tggcgccgag gcgctgcacc
     3121 accttcacct cggcgcgcgc cagatgctgg cgcgtcagca ccaggcagtc ggcgagcgcg
     3181 gcattgacgt cgacgtcctc gacgtagccg gcgaactcgt ccgggcgggc gaactgcagc
     3241 agcttggtga cgatcaggcg gatgcgcccg acctgctcgt ggatcaggcg aatctcgttg
     3301 gccaccggct gcgccgccgg gccgagttcc tcgcgcagca ggtcgaggtt gccctggatc
     3361 accgcggtcg ggttgctgat ctcgtgtgcg acgccggcgg tgagctcgcc gatcgcggcg
     3421 agcttctcgc tcatcaccag gcggtgctgc gctgcacgca gctcttcgtt ggccgcggcg
     3481 aggtcggcgg tgcgctcggc gaccttgcgg tccagcgagg cgttgagcgc ctgcagctcg
     3541 gcacgccgcg cggcctgctc ttcgagcaga tggtcgaagg ccgtggccag gcggccgagc
     3601 tcgtcgcggc tggcgacgtc gccgacacgc gcatgctcgt cgccggcgtc gatgcgaccg
     3661 atggtggcgt gcatgcgctc gatcgggcgg aagatgccgc gcgcccagaa caacgtgagc
     3721 agcgcgcccg cggcactcac cagcagcgcg agcgcgccga ccacgagcag ggccgtgcgc
     3781 ttggcggcgc ggaagggggc ctcgaggaag ccgacgtaga gcatgccgac gcgctcgccg
     3841 cggctgtcca tcaccggctc gtaggcggac acgtaccagt cgttgaccac gaacgcggtc
     3901 tccagccagg tgcgcccatg gtcgagcaca tgcgcgcgca cctcgtccga cgcgcgcgtg
     3961 ccgagcgcgc gcgcgccctc gaacaggcgc acgttggtgg cgatgcgcac atcgtcgacg
     4021 aagagcgtgg cggtgccctc gctgccctcg ggcaggctgc cctcgcggta gacgatggcg
     4081 ttgagcgtgt cgacgaagtc gaggttgccg ttgagcagca cgccgccttc gagcaccgcg
     4141 accagattgc ccgcggcgtc gagcaccggg gccgcggcgt gcacgaccag tccgcgctct
     4201 tcctcgggac gcggatcggg ccgcgcgcgc ggagtcgcca ccagggcgag gcgggcgcgc
     4261 tcgcgcagcc cgacgtcgat cgccgcgagc tcggcggcag cgaagcgctc gacgacgctg
     4321 ccgccgcgag cgccgatggc ccgctgcacg acgctccagt cgccgcgcgc gctgcccgcc
     4381 gccatcgcgg tcgaggagtg cagcacgcgg ccgttcacat cgagcaggtt gaggaagtcg
     4441 agcgcgagcc cgcccttgcg cgcgccgagc agcgccgcga ccgcctccgg cgtctcgtgc
     4501 gccagggact gcgcgagcgc gtgcgacccg gcgagcgcct gcacgcggct gccgacgccg
     4561 tcgatcacgc gctcgaagta gccgtgcgcg gtcgccaggt cgctggcgac gcgcgatacc
     4621 atcaggcggt ggtagtagac ctcgccccag taccacagca ggcccatgat cagcgggaag
     4681 ccgagcatca gcggcgcgag cacgagggcg agcagcttgg cgcggacgga gccgcgcagg
     4741 cgttcggcga ggctcatcgc cacgcccccg cgcaagcgcc tgccgtgcgg cgcgacctgc
     4801 ccgccccgac cctcgccacg ctcaggcccg ccgctccgcg cgcgttgccg cggcgtcctc
     4861 gagcgcccac tcggcaaact tgcgctcgag cgtcttgcgc gagacaccga gccggcgcgc
     4921 ggcctcggtc ttgttgccct cgcaggccgc ggtcacgcgc tcgatgtggc ggcgctcgac
     4981 ctcggccagg ctcagctcca gctcgcccgc cggcgtcggc gcggcagtgg gcgccgcgct
     5041 cggctgcggc gggaaacagc ccaggatcag cgagcgctcg acgtagttgc gcagctcgcg
     5101 cacgttgccc ggccaggaat agccggccag ccggctcacc acctcgtgcg acagcggcag
     5161 cggcggcacg ccgagctgga cggcgagctg ctgcatgaag tggcgcatca gctcggggat
     5221 gtcctccgcc cgggcgcgca gcggcggcag ggcgatatcc accacggcga gccggtagta
     5281 gaggtcctcg cggaagcgtc cgacgcgcac ctcggcagcg aggtcgcgat tggaggcggc
     5341 gatgatgcgc acgtccaccg gcagctcgcg ctcggagccg accggacgca gcttgcgctc
     5401 ctcgagcacg cgcagcagcc gggtctgcat cgccagcggc agctcgctga tctcgtcgag
     5461 gaagagcgtg ccgccgtggg cgtagtagaa caggccattg cggctctcgc tggcaccggt
     5521 gaaggcgccc ttgacgtggc cgaagagctc gctctcgatc agctcggagg cgatcgccgc
     5581 gcagttgagc ggcacgaagg ggcgctgcgc gcgcgggctg gtctggtgca gggcgcgcgc
     5641 caccacctcc ttgccggtac cggactcgcc cagcagcagc accgtgctcg gcatctgtcc
     5701 gacgcggcgc accagcgcgc gcagttgctc catcgcgggc gaatggccga tcagcccggt
     5761 gggttcggcg cccaggccgg cgagttcgcg gcgcagcacg aagttctcgc gcgcgaggcc
     5821 ggcgcgctcg aagcagcgct tgatcgaatt gaggatctgg tcgacgcgga agggcttgag
     5881 gatgaagtcc gaggcgccgc cgcggagggc gtcgatcgcg gtctccatgt cggcgaaggc
     5941 ggtgatcagg atcacgtcgc cggcgtagcc gtgctcgcgc agctcgtgca gccactcgat
     6001 gcccgacttg ccgggcaggg cgatgtcgag cacgagcagg tcgaagtgca gccgcgccat
     6061 cagcgccgcg gcgtgctcgg catcggcggc cgactgcacc atgccgcagc ggcgcgcgag
     6121 cgtgcgctcg aggaagttgc gcatgccctc ctcgtcgtcc accaccagca ccgagtgcgc
     6181 cggccagtcg tagtcggcga gctccaccgg gcgcgcaggc gcgatgccct cccccggcgc
     6241 cgcgcccgcc cctgctgcgg ccgccccgca gtctccgccg tgaggtttcg cgaccatgct
     6301 cagaagggct tcagcaccac gaggaacacc accacgaaca gcaccagcac ggggatctcg
     6361 ttgaaatagc ggtaccacac gtggctgcgc gtgttgcgtc cttcggcgaa ggcgcgcatc
     6421 aggcggccgc aatacaggtg gtaggcgatc aggaacacca ccagcagggt cttcgcgtgc
     6481 agccagccac ctgcgaagcc gtagccgaac cacagccaca ggccgaggcc cacggcgagg
     6541 atgccgagcg gggtcatgaa gcggtagagc ttcatctcca tcatggccag gcgatcgcgg
     6601 gtggcggcgt cctcgaccat ggcgtggttg acgaagaggc gcggcaggta gaagaggccg
     6661 gcaaaccagc tcacgacgaa gacgatgtga aaggccttga gggtcagcat gcggggaagg
     6721 gctccaggtt cgatcgaaga gggtgtcttg cggtgccgcg gctcaggcgg cggggacggt
     6781 cgcggctcgc agcccgtcgg ccaccgtcgg atagcg
//
LOCUS       DAOTIN010000158         6799 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_13297_length_6799_cov_8.157325, whole genome shotgun sequence.
ACCESSION   DAOTIN010000158 DAOTIN010000000
VERSION     DAOTIN010000158.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 6799)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 6799)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6799
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_13297_length_6799_cov_8.157325"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(293..718)
                     /locus_tag="P5537_15460"
     CDS             complement(293..718)
                     /locus_tag="P5537_15460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004337182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family
                     toxin"
                     /protein_id="HRV79485.1"
                     /translation="MSFVLDNSVAMCWLLADGKPADVAYAEAVLDALREQQALVPSLW
                     ALEASNVIARAEAKGLLSEARSQAFLVLLQRLNIATDPATAAHALGDTLHLARRYKLS
                     AYDAAYLELALRTGLPLATLDADLEKAAQAAGVEAFAPN"
     gene            complement(715..963)
                     /locus_tag="P5537_15465"
     CDS             complement(715..963)
                     /locus_tag="P5537_15465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system
                     prevent-host-death family antitoxin"
                     /protein_id="HRV79486.1"
                     /translation="MMNLEIGSYEAKTKLPELLRGVQAGKRYTITLRGEPIADLIPAE
                     GAKQAHAAAAVDAMRQFMRAAPAVEGIDRKALINEGRA"
     assembly_gap    1450..1549
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            1726..2484
                     /locus_tag="P5537_15470"
     CDS             1726..2484
                     /locus_tag="P5537_15470"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79487.1"
                     /translation="MTMKILDTRKFALAALVGSLSFAPAAFAADSAAEVQKKRLTAAE
                     KAELKKRWQMTSDELEKSLGVGHDKAYYRQALEKMGYAITAKNYDEPDYLEYEIVKGD
                     ESYEVQVDLENGKSDKVDVTVNMWRADTTVAALRDKNYKYVYPATLSAAAEKFSDRAR
                     AKLWSGEKDQLENALGTGHERGYYRPALEKLGYRVTAVNDNDANHLEYEIVKGDQSYE
                     VMIDFDADTKKANEVDVETNIWEAERTEKAKGDE"
     assembly_gap    2790..2889
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(2988..3944)
                     /locus_tag="P5537_15475"
     CDS             complement(2988..3944)
                     /locus_tag="P5537_15475"
                     /inference="COORDINATES: protein motif:HMM:NF036542.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catalase-related domain-containing protein"
                     /protein_id="HRV79488.1"
                     /translation="MANNQRDGMHRQAVHRGKVAYEPNSLGGGCPFQAGMKGYVSHPA
                     LVEEAPKLRGKPEKFAEHYLQARLFWDSLGAVERVHLEGAFRFELSKVTVPAVRERMI
                     ASLRNVDEGLAARLATALGVELPAALPRALDKLPKPEVKCSSALSQTAYPGDGSIATR
                     KVALLVAEGVSAKALRLLAEALGEQGAVPVHVGPLLGVVRADRGELPVDATYENSPSV
                     LFDAVVLPADEASLAALDAHADAVGDFVREQYRHGKAIGLAGGAPQVLARWGIALDRK
                     GKTDGRLAGVVDCAAGAGAFFNAIARHRHPERERLPDWAQAD"
     gene            complement(3836..5356)
                     /locus_tag="P5537_15480"
     CDS             complement(3836..5356)
                     /locus_tag="P5537_15480"
                     /EC_number="1.11.1.6"
                     /inference="COORDINATES: protein motif:HMM:NF012425.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004096 - catalase activity [Evidence
                     IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catalase"
                     /protein_id="HRV79489.1"
                     /translation="MNEANKGGKPITALPDDLERRNPQLARHAAAGQRLAVQRPHNAD
                     KRTEYAEGAALAAAPEGEHVDAEPADLAGTLSEAQPGEKTGAEVTRELAGALPPGSLA
                     HARVAPAVEPMTTNQGVPMADDQSTLKAGVRGPSLLEDFILREKLTHFDHERIPERVV
                     HARGSAAHGYFECTADLSGLSRAKVFTKGKRTPVFARFSTVAGERGSADCARDARGFA
                     VKFYTEEGNWDLVGNNIPVFFIQDAMKFPDLVHAVKPEPHNGIPQAASAHDTFWDFVS
                     LMPESTHMLMWAMSDRAIPRSLRMMQGFGVHTFRLVDAAGKASLVKFHWTPKAGVHSL
                     VWDEAVKLNGADPDFHRRDLWEAIEAGAYPEWALGLQVFSEQEAAGWSFDVLDATKLV
                     PEELCPVRTVGRMVLDRNPDNFFAETEQVAFCTAHVVPGIDFTNDPLLAGRHHSYHDT
                     QLSRLGGPTLPSCRSTLRSRAWPTTSATACTARRCIVARWPTSPTRSAAAAPSRLA"
     gene            complement(5353..5946)
                     /locus_tag="P5537_15485"
     CDS             complement(5353..5946)
                     /locus_tag="P5537_15485"
                     /inference="COORDINATES: protein motif:HMM:NF013936.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemerythrin domain-containing protein"
                     /protein_id="HRV79490.1"
                     /translation="MANIEYRNPFRRMRMANNPKSKRTASSSASKRTRTPDAIALLKA
                     DHREVKDMHAHFEKLAEEGAAASEREALARRICAALRVHARIEEEIFYPAVKPVIDDD
                     LLLPEAKVEHDSARDLIEQIESSSPKDELFDARVIVLGEYVQHHVKEEEREMFREVRA
                     SKELDLRALGKQMQARKEELMAGFKESADKKEKETAK"
     gene            complement(5988..6179)
                     /locus_tag="P5537_15490"
     CDS             complement(5988..6179)
                     /locus_tag="P5537_15490"
                     /inference="COORDINATES: protein motif:HMM:NF016141.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HRV79491.1"
                     /translation="MNFILWILVGVVGALIAGWIISPLVGIPTINQDVFSLPALLVSL
                     LGAIVLLGVVNLVRRGRIR"
     gene            complement(6176..6349)
                     /locus_tag="P5537_15495"
     CDS             complement(6176..6349)
                     /locus_tag="P5537_15495"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79492.1"
                     /translation="MTRKADPIQSPEDLFTRIALPPPSCSPALRRDSSRFARIAAAPR
                     PGPRRRFITENTQ"
     gene            complement(6442..6645)
                     /locus_tag="P5537_15500"
     CDS             complement(6442..6645)
                     /locus_tag="P5537_15500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HRV79493.1"
                     /translation="MNWDRIEGNWKQLKGKAKEQWGKLTDDDFDVAAGKRDQLAGRVQ
                     ERYGIARDEAERQVDTWADNFKD"
BASE COUNT         1102 a         2219 c         2200 g         1078 t
ORIGIN      
        1 gatagctgca tccgcgctgc ggtccgcgca cgctgggcgc acgcagcaac atcctgcgtg
       61 ccgccgccca tgccgctcca gcggtcagcg cccggacttt gccgagccgc ctttctcccc
      121 cgggagaccg gcgatattcg cacccacttc actcggtgcg ccgcttcagc ctcccaccct
      181 tggtaatcaa ggacaacttc ctcgacaagc ttcatctcga cgtcaagggc ggcgacttca
      241 cggccatcgc cgatcagccc atccgctaca agggcgacgg ctcggcgtcc ggtcagttcg
      301 gcgcgaatgc ctccacgccc gcggcctgcg ccgccttctc gagatctgcg tccagggtcg
      361 cgagcggcag gccggttcgc agggccagct ccagatacgc cgcgtcgtac gccgatagct
      421 tgtaacgccg ggccaggtgc agggtgtcgc ccaaggcgtg cgcggcggtg gcgggatcgg
      481 tcgcgatgtt cagtcgctgc aggaggacga ggaaggcctg cgagcgtgcc tcgctgagca
      541 gccccttggc ctcggcccgg gcgatgacgt tgcttgcctc gagcgcccac agcgacggga
      601 ccagcgcctg ctgctcacgc agcgcatcga gcacggcctc ggcgtacgcc acatcggccg
      661 gcttgccatc ggccagcagc cagcacatcg ccaccgagtt atcgagcacg aagctcatgc
      721 ccgcccctcg ttgatcagcg ccttgcggtc gatcccctcg acggccggtg ccgcgcgcat
      781 gaactggcgc atcgcatcga cggccgccgc ggcatgcgct tgcttggcgc cttcagccgg
      841 tatcaggtcg gcgatgggct cgccacgcag ggtgatggtg tagcgcttgc ccgcctgcac
      901 gccgcggagc agttcgggca gtttggtctt ggcctcgtat gagccgatct caaggttcat
      961 catgttctcc ggttgcaata gactagttta tagaccagtt gacaagagaa tcaagcacgg
     1021 catcaacacg cgcaccagcg gtgaagccgc gccaggtggc acaagacggc atgcgggggc
     1081 gggccagtgc gggggcggga tcgttccggc gcgtgcatcg acgaccgatg ctcaggcgac
     1141 ggtcttgatg aagatgggcg acggccggtt tcggtgtgtg cgtggcaacc cttgtgcgct
     1201 gcggcgagac aagcagaccg ccggcgtata gcctgtcgtc ggcttcacga cgtgatatat
     1261 gtgaagccca acaaaaccac atgattccag gaggacgacc atgtcttaca cgatgcccga
     1321 atttctcgcc cacgcgatcg ccatggaacg cgaggccgcc gaacgctacc ttgaactcgc
     1381 cgacatgatg gaggcgcaca acaacctcga ggtcgcctcg ctgttccgcg acatggtgcg
     1441 ctactccaan nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnc ggtcggcgcc
     1561 gtcctgcacc gcctgtcgga cctgtccgac aagcggatcg ggcatcgacg gacatttccg
     1621 acgaatcgaa gtgcatacca tggtttccgc agtcggacga aacgaccgac cgatgcaggc
     1681 cccggagccg cagtgctccc gggtacccca gccccaacgg agaccatgac gatgaagatc
     1741 ctcgacaccc gcaagttcgc cctcgccgcc ctcgtcggca gcctctcgtt cgctccggcc
     1801 gccttcgccg ccgacagcgc tgccgaggtt cagaagaagc gcctcactgc cgccgaaaag
     1861 gccgaactca agaagcgctg gcagatgacc tccgacgagc tcgagaagtc gctcggcgtg
     1921 ggccacgaca aggcctatta ccgccaggcg ctggagaaga tgggctacgc gatcaccgcg
     1981 aagaactacg acgagcccga ctacctcgag tacgagatcg tcaagggcga cgagtcctac
     2041 gaggtccagg tcgacctcga gaacggcaag tccgacaagg tcgacgtgac ggtgaacatg
     2101 tggcgcgccg acaccaccgt cgccgccctg cgcgacaaga actacaagta cgtctatccc
     2161 gccaccctga gcgccgcggc cgagaagttc agcgaccgcg cccgcgccaa gctgtggtcc
     2221 ggcgaaaagg accagctcga gaacgcgctc ggcaccggcc acgagcgtgg ctactaccgc
     2281 cctgccctcg agaagctcgg ctaccgggtc accgcggtca atgacaacga cgcgaaccac
     2341 ctcgaatacg agatcgtcaa gggcgaccag agctacgagg tcatgatcga cttcgacgcc
     2401 gacacgaaga aggcgaacga ggtcgacgtc gagaccaaca tctgggaagc ggagcgcacc
     2461 gagaaggcca agggcgacga gtaagcccgc gcgcaagtct cctcctccgg cgcggccgga
     2521 gcccctcccc tcctccaccg cgccctccac ggccgggtcg acaacgaccc ggccgttttt
     2581 ccgtcgacgg tcccgtgtgg cagcctctgc cgccgtcgcg ggctgggttc gcgacttccc
     2641 tccactggct ccggcatcgt accgccgcga cgaactcgcc caccgccctc gcgggtgcac
     2701 ttcgccttcc actgcccctg cccatgcgcc atgaggatca accgccgcaa cgcaagcgcg
     2761 aggcggtcag gcccatccga tcgcccttgn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2821 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2881 nnnnnnnnnc ggggcgcgag gacgaacgca caaaagcgcg ggacgacggc ctgaaccgtc
     2941 gtcccgcgcc gggatattgc agcgagtcga gcccgctgcc tcagccctca gtcggcctgc
     3001 gcccagtcgg gcagccgttc gcgctcgggg tggcgatggc gggcgatcgc gttgaagaag
     3061 gcccccgcgc ctgcagcgca atcgaccacg ccagcgaggc gcccatcggt tttgcccttg
     3121 cggtcgagcg cgatgcccca gcgcgcgagc acctgtggcg ctccaccggc gagcccgatc
     3181 gccttgccgt gacgatattg ctcgcggacg aaatcgccga cggcgtcggc gtgcgcatcg
     3241 agcgctgcga gcgaggcctc atcggccgga aggacgacgg cgtcgaacag caccgacggg
     3301 ctgttctcgt aggtcgcatc gaccggcaac tcaccacggt ccgcgcgcac cacaccgagc
     3361 agcggcccga catggaccgg cacagcgccc tgctcgccga gggcctccgc gagcaggcgc
     3421 agcgccttgg cggaaacgcc ctcggcgacc agcagggcga cctttcgggt cgcaatcgag
     3481 ccgtcccctg ggtaggcggt ctgcgacagg gcggacgaac acttcacttc gggcttgggc
     3541 agtttgtcga gcgcgcgcgg cagtgctgcg ggcaactcga cgccgagcgc agtggcaagg
     3601 cgggcagcga gcccctcgtc gacgttgcgc aggctggcga tcatgcgctc acgcacggcc
     3661 ggcacggtga ccttgctcag ctcgaagcga aaggcgcctt ccaggtggac gcgctcgacc
     3721 gcgcccaggc tgtcccagaa cagccgggct tgcaggtaat gctcggcgaa cttctccggc
     3781 ttgccgcgca gcttgggcgc ctcctcgacc agcgccgggt gggagacgta gcccttcatg
     3841 ccagcctgga aggggcagcc gccgccgagc gagttgggct cgtaggccac cttgccacga
     3901 tgcaccgcct ggcggtgcat gccgtcgcgc tggttgttgg ccacgcgcgc gagcggagcg
     3961 ttgatcggca gctcggtaaa gtggggccac ccagccggga gagctgggta tcgtggtagg
     4021 agtggtggcg accggcgagc agcgggtcgt tggtgaagtc gatgcccgga acgacatggg
     4081 cggtgcagaa ggcaacctgc tcggtttcgg caaagaagtt gtccgggttg cggtcgagca
     4141 ccatgcgacc gacggtgcgc accggacaca gctcctccgg caccagcttg gtggcgtcga
     4201 gcacgtcgaa gctccagccc gcagcctcct gttccgaaaa cacctgcagg ccgagcgccc
     4261 attccgggta ggctccggcc tcgatcgcct cccacaggtc gcggcggtgg aagtcggggt
     4321 cggcgccgtt gagcttgacc gcctcgtccc acaccagcga atgcacgccg gcctttggcg
     4381 tccagtggaa cttgaccagg ctggccttgc ccgcggcgtc gacgaggcgg aaggtatgca
     4441 cgccgaaacc ctgcatcatg cgcagcgagc gcgggatggc gcggtcgctc atcgcccaca
     4501 tcagcatgtg ggtggactcg ggcatcagcg agacgaagtc ccagaaagtg tcgtgcgcgc
     4561 tggccgcctg cgggatgccg ttgtgcggct cgggcttgac ggcatgcaca aggtcgggaa
     4621 acttcatcgc gtcctggatg aagaacaccg ggatgttgtt gccgacgagg tcccagttgc
     4681 cttcctcggt atagaacttg accgcaaagc cgcgcgcatc gcgcgcgcag tcggccgagc
     4741 cacgctcgcc ggcgaccgtg gagaagcgcg cgaacaccgg agtgcgcttg cccttggtga
     4801 agaccttggc gcggctgagg ccggagagat ccgcggtgca ctcgaagtag ccgtgcgcgg
     4861 ccgagccgcg cgcgtgcacc acacgctcgg gaatgcgctc atggtcgaag tgggtgagct
     4921 tctcgcgcag gatgaagtct tcgagcaggc tgggcccgcg cacgccggcc ttcagggtgg
     4981 actgatcgtc cgccatcggc acgccctggt tggtcgtcat cggctcgacc gcaggggcga
     5041 cgcgcgcatg cgcgaggctg cccggcggca acgcgccggc aagctcgcgg gtgacctccg
     5101 cgccggtctt ttcaccgggc tgcgcctccg aaagagtgcc ggcgaggtcc gccggctccg
     5161 catcgacatg ctcgccctcc ggcgctgcgg caagtgccgc gccctcagcg tactcggtcc
     5221 gcttgtccgc gttgtgcgga cgctgtacgg ccagacgctg tcccgccgcc gcgtgtcgcg
     5281 caagttgcgg attgcgacgc tcaagatcgt ccggcaatgc ggtgatcggc ttgccgccct
     5341 tgttcgcctc gttcatttgg cggtctcctt ttccttcttg tccgcagact ccttgaagcc
     5401 ggccatgagc tcttccttgc gcgcctgcat ctgcttgccg agcgcacgca gatccagctc
     5461 cttcgatgca cgcacctcgc gaaacatctc gcgctcctcc tccttgacgt ggtgctggac
     5521 atattcgcca agcacgatca cgcgcgcatc gaagagttca tccttgggag acgaggactc
     5581 gatctgctcg atcaggtccc gtgccgagtc gtgctcgacc tttgcctccg gcaacagcag
     5641 atcgtcatcg atgacgggct tgactgccgg gtagaagatc tcttcctcga tgcgcgcgtg
     5701 cacacggagc gccgcgcaga tccggcgcgc cagcgcctcg cgctcggagg cggcagcacc
     5761 ctcctcggcg agcttttcga agtgagcgtg catgtccttg acttcccgat gatcagcctt
     5821 gagcagggcg atggcgtccg gcgttcgggt gcgcttcgaa gccgacgaag aggcggtgcg
     5881 cttggacttg ggattgtttg ccattctcat tctcctgaag ggattccgat attcgatgtt
     5941 ggccatacgg acacggcgac cacgcgcctt gcgttcgcga ggcgagctca gcggatacgg
     6001 ccgcggcgca cgaggtttac gacaccgagc agcacgatgg cgcccagcag cgagacgagc
     6061 agcgcgggca ggctgaagac gtcctggttg atggtgggga tgcccaccag cggcgagatg
     6121 atccagcccg cgatgagcgc gccgaccacg ccgacgagga tccagaggat gaagttcatt
     6181 gcgtgttctc cgtgatgaag cgcctgcgcg gcccggggcg cggcgcggcg gcgatgcgcg
     6241 cgaagcgcga gctgtcgcga cgcaaggccg gcgaacagga cgggggcggg agggcgatgc
     6301 gggtgaagag gtcttctggg gattggatgg ggtcggcttt tcgggtcatg gcggcggcgg
     6361 gtcggtcgtt ccgggcgttg tcgtgtgctc gggaagaaag gggcggccgc cccccgaagg
     6421 gaacggccgc ggggtgctgg atcagtcctt gaagttgtcg gcccaggtgt ccacctggcg
     6481 ctcggcctcg tccctggcga tgccgtagcg ctcctgcaca cggccggcga gctggtcgcg
     6541 cttgccggcg gcgacgtcga agtcgtcgtc ggtgagcttg ccccactgct ccttcgcctt
     6601 gcccttgagc tgcttccagt tgccttcgat gcgatcccag ttcatggctt tctccttttc
     6661 tctgtcgtgt cgtgcgccac ggggggcgcc gggtttgcgg tcgatcgtgt gtcgtccggc
     6721 gagacccatc ttccgcgatc gggcaggcac gctgaatagg acgaaggcgt ctgcatttgt
     6781 aggaatcgat gaagggatg
//
LOCUS       DAOTIN010000159         6593 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_13820_length_6593_cov_6.346742, whole genome shotgun sequence.
ACCESSION   DAOTIN010000159 DAOTIN010000000
VERSION     DAOTIN010000159.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 6593)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 6593)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6593
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_13820_length_6593_cov_6.346742"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            175..1893
                     /locus_tag="P5537_15505"
     CDS             175..1893
                     /locus_tag="P5537_15505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004377086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV79494.1"
                     /translation="MPSRFIRSEQPEALRRGLGWLYAFVRPQRGAILRLLALSLLASA
                     LVLLQPWLTKLLIDDGLLARDYPTLVMVAAAMIAAGLAGTALAGINRLLHTRLSGTIL
                     FALRSDLYRHLQGLSPSFYGRQRLGDLMSRIDGDVAEIQRFAVDSLFAAVSSVIGLLG
                     ALAMMIGLSWKLSLLVLVLVPLEVVWLRHMRRRLETRTRTVRERAADVSSFLVETLPA
                     MKFIQSSRREADERARLDALGARYLDELLGLQRTEFLTHALPSTLTSLTRAGAFLIGG
                     WWVIEGDWQLGALIAFSTYLGMATGPVGSLLGLYVAVQRMSVSLMRVGELREATAEVA
                     DPPAAVAVPPAWRGRVELDGVVFRHRGRAEAVLDGASLVIPAGSKVALTGASGVGKST
                     LIDLLHRHYDPAAGVLRLDGVDLRTISLGELRRAVAVVSQDIVLFRGTLADNIRYAMP
                     AADDEAVRLAAHRARLDELVAALPQGLATPLAERGQQLSGGQRQRIAIARALLQDPCV
                     LVLDEATSAVDEATEAAVIAEVDALFADRTRILVSHRAATRVGCELELRLEAGRLEPV
                     VRAQGD"
     gene            1894..2607
                     /locus_tag="P5537_15510"
     CDS             1894..2607
                     /locus_tag="P5537_15510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HRV79495.1"
                     /translation="MGAAVRLGLIDSGCSAAHASNVVAAAAFGVQDGVVRRGDAQPDR
                     LGHGSRIADVLLHFLPQAELVVAQVFGERLTTSALQVAAAIDWAVANEAHILNLSLGL
                     RAPRAVLAEACARAHAAGVLLCAAAPTRGAPVFPAAFADMLRVTGDARCAREEVAALG
                     AAHADFGAHVRPLDGTLSGAGASMACAHVSGLAARHFAAGGGPASLRAWLQAQARFHG
                     VEDRAREAAARAARTDDSR"
     gene            complement(2636..3703)
                     /locus_tag="P5537_15515"
     CDS             complement(2636..3703)
                     /locus_tag="P5537_15515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004386876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HRV79496.1"
                     /translation="MKIVAPIRQLDEIAALARAGADELYCGVTPREWAERFGGASANR
                     RPGGNLPSLAVLAEAVELAHRHGVQLSLVLNAQQYSVEQIEFALEIACGYADIGGDAV
                     IASDPGLILALAEAVPGLRIHVSSVATCRNADGARLYQELGARRLILPRDITLDEAAE
                     IAAAVPDLEIEAFVLNDGCVYEEGSCNTLHLPGALGGPICLDRYAYVHRHRDGRPLSA
                     TLAARLQENDEAYRRWLWYRFSCGFTTTAEGMPFGPCGLCAIPALGRGGVHALKIAGR
                     EGPPERKLASVRMVRQILDAHERGESPAAVMARARELRPSHEHCATGFMCYYPEVVGE
                     AERARETGRHAPSSSPTPTSD"
     gene            complement(3714..4682)
                     /locus_tag="P5537_15520"
     CDS             complement(3714..4682)
                     /locus_tag="P5537_15520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79497.1"
                     /translation="MSAPLTFLRRPPASPPTGVSAASPTALAALPASGVAIAVSMVRP
                     RALDRLCAGPPARAAFWSATLHDQALADWLAPLRPTRLHVGSEFCERLLPEPEQLERT
                     LAEASAAGLAVCLLTPVASPEVLRALEPLFALLPAGAEVVVNDWGVALRLHERHPLLQ
                     AVAGRILCRMLKDPRLGNPQYAPPAAHGFASPWQQRLFARMGITRVEMDMPLFAGADS
                     FAGVPLPLGVHLPFAFVAKGRMCRTAGLARPGPERFAPRPFCHHECLGLAARTERARE
                     GTHDAWETLHVGNTVFCRHSAASLAVLAAAVAAGRVARLIVPGEAL"
     gene            complement(4683..6104)
                     /locus_tag="P5537_15525"
     CDS             complement(4683..6104)
                     /locus_tag="P5537_15525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HRV79498.1"
                     /translation="MNKTPSLVIDGRKVAGDRGTLPVIDPALGEAFAECPNASPAQLN
                     AAVAAAGRAFEQWQHSTCEERRALLEAIAARIEQNAPELAEIIVREQGKPLALAHMEV
                     GGAVAWTRATAALELPVEVIEDRPGKRIELHRRPLGVVGSITPWNWPLMIAVWHIMPA
                     LRAGNAVVIKPSELTPLNTLRLVELIDEVAPPGLVNAVAGGGALGREISGHRGIQKIV
                     FTGSTRTGQDIMRNAADTLKRLTLELGGNDAGIVLPGTDIGAIAEGVFGSAFLNMGQT
                     CAALKRLYVHESQYEDMCRHLVAIAARQKVGNGLDEGTSFGPIQNRDQFERVCELVED
                     ARAAGARILCGGEPLPGKGYFYPPTIVADIADGTRLVDEEQFGPVLPVIRYRDVDEAV
                     RLANASTNGLGGSVWSGDPEAARAVANRLECGTVWINGHAEVLPHCPFGGCKMSGFGV
                     EFGLEGLLEYTRPQLLNINLPTS"
BASE COUNT          836 a         2320 c         2495 g          942 t
ORIGIN      
        1 cttttgcaga gctacgtgga cgaccgcctg ctggtcgagc cgatctactg atcgcatccg
       61 tcgcggggcg ccgggcggga gcgtaggccg ccgtccgcag tgcggctggc cgggacggcg
      121 ggcgatacaa ttcccgtcct tccaccattc gccgcatccg gccgagggcg gtccatgccg
      181 agccgcttca tccgtagcga gcagcccgag gccttgcgcc gcgggctggg ctggctgtac
      241 gccttcgtgc gcccgcagcg cggcgccatc cttcgcctgc tcgcgctgtc gctgctcgcc
      301 tccgccctgg tcctgctgca gccctggctg accaagctgc tgatcgacga cggcctgctg
      361 gcgcgcgact acccgacgct ggtcatggtc gcggccgcga tgatcgccgc gggcctggcg
      421 gggacggcgc tcgccggcat caaccgcctg ctgcacacgc ggctctccgg caccatcctg
      481 ttcgccctgc gcagcgacct ctaccgccat ctgcagggcc tgtcgccgag cttctacggc
      541 cgccagcgcc tcggcgacct gatgtcgcgc atcgacggcg acgtcgccga gatccagcgc
      601 ttcgcggtcg acagcctgtt tgcggcggtg agcagcgtga tcggcctcct cggtgcgctc
      661 gcgatgatga tcgggctgtc gtggaagctg tcgctgctgg tgctcgtgct ggtgccgctc
      721 gaggtggtgt ggctgcgcca catgcggcgc aggctggaga cgcgcacgcg caccgtgcgc
      781 gagcgcgccg ccgacgtatc gagcttcctg gtcgagaccc tgccggcgat gaagttcatc
      841 cagtcctcgc ggcgtgaggc cgacgagcgc gcccgcctgg acgcgctggg tgcgcgctac
      901 ctcgacgagt tgctcggcct gcagcgcacc gagttcctca cccatgcgct gccctccacg
      961 ctcacctcgc tcacgcgcgc cggggccttc ctgatcggcg gctggtgggt gatcgagggc
     1021 gactggcagc tcggcgcgct gatcgcgttc tcgacctacc tcggcatggc gaccgggccg
     1081 gtcggcagcc tgctcggcct ctacgtcgcg gtccagcgca tgagcgtgag cctgatgcgg
     1141 gtgggtgagc tgcgcgaggc gaccgccgag gtggcggacc cgcccgctgc ggtggcggtg
     1201 ccgccagcct ggcgcgggcg ggtcgagctc gacggcgtgg tcttccgcca tcgcgggcgc
     1261 gcggaggccg tgctcgacgg cgccagcctg gtgatcccgg cgggcagcaa ggtggcgctg
     1321 acgggcgcct cgggcgtggg caagtccacg ctgatcgacc tgctgcaccg ccactacgat
     1381 ccggccgccg gcgtgctgcg cctggatggc gtcgacctgc gcacgatctc gctgggagag
     1441 ctgcgccgcg ccgtggccgt ggtgagccag gacatcgtgc tgttccgcgg gacgctcgcc
     1501 gacaacatcc gctacgcgat gcccgcggcc gacgacgagg cggtgcggct ggcggcgcac
     1561 cgggcgcgcc tggacgagct cgtggcggcc ctgccgcagg gcctcgcgac gccgctcgcc
     1621 gagcgcgggc agcagctctc cggcggccag cgccagcgca tcgcgatcgc ccgcgccttg
     1681 ctgcaggatc cctgcgtgct ggtgctcgac gaggcgacct cggcggtgga cgaggcgacc
     1741 gaggcggcgg tgatcgccga ggtggacgcg ctcttcgccg accgtacccg catcctcgtc
     1801 agccatcgcg cggcgacccg ggtggggtgc gagctcgagc tgcggctcga ggccggccgc
     1861 ctcgagccgg tcgtgcgcgc gcagggggac tgaatgggcg cagcggtccg cctcggcttg
     1921 atcgacagcg gctgcagcgc cgcgcacgcg tcgaacgtag tcgcggcggc ggccttcggg
     1981 gtgcaggacg gcgtcgtccg ccgcggcgac gcgcagcccg accggctcgg gcacggcagc
     2041 cggatcgccg atgtgctgct gcacttctta ccgcaggccg agctggtcgt ggcgcaggtg
     2101 ttcggcgagc gcctgaccac gagcgcgctg caagtggcgg ctgcgattga ctgggcggtc
     2161 gcgaacgaag cacacatcct caacctcagc ctcggtctgc gcgcaccccg cgcggtgctg
     2221 gccgaagcct gcgcgcgcgc gcacgccgcc ggcgtgctgc tgtgcgcggc ggcgcccacg
     2281 cgaggggcgc cggtgttccc ggcggccttt gcggacatgt tgcgggtgac cggcgacgcg
     2341 cgctgcgcac gtgaggaggt ggctgcgctc ggcgccgccc atgccgactt cggtgcgcat
     2401 gtacgcccgc tcgacggcac gctttccggg gcgggcgcga gcatggcctg cgcgcacgtg
     2461 agcggcctgg ctgcgcgcca cttcgccgcc gggggcggtc cggccagcct gcgtgcctgg
     2521 ctgcaggcgc aggcgcgttt ccacggggtg gaggaccgtg cccgcgaggc ggcggcgcgc
     2581 gcagcgcgca cggacgattc gcgctgagcg gcgcaggcgc ggccgcggcg ccgtctcagt
     2641 cggaggtggg ggtgggggag ctcgagggcg cgtgccgccc cgtctcccgc gctcgctcgg
     2701 cctcgcccac gacctcgggg tagtagcaca tgaagccggt cgcgcagtgc tcgtgcgaag
     2761 gccgcagctc gcgcgcgcgc gccatcaccg ccgcgggcga ttcgccgcgc tcgtgggcgt
     2821 cgaggatctg cctgaccatg cgcacgctgg cgagcttgcg ctcgggcgga ccctcgcgcc
     2881 cggcgatctt gagcgcgtgg acaccgccgc gcccgagcgc cgggatcgcg cacaggccgc
     2941 aggggccgaa gggcatgcct tccgcggtgg tggtgaagcc gcaggagaag cggtaccaca
     3001 gccagcgccg gtaggcctcg tcgttctcct gcaggcgggc ggcgagtgtc gccgagagcg
     3061 gccggccgtc gcggtggcgg tgtacgtagg cgtagcggtc gagacagatc gggccgccga
     3121 gtgcgccggg caggtgcagg gtgttgcagc tgccctcctc gtagacgcag ccgtcgttga
     3181 gcacgaaggc ctcgatctcg aggtcgggta ccgcggcggc gatctccgcg gcttcgtcga
     3241 gcgtgatgtc gcgcggcagg atcagccggc gcgcgccgag ctcctggtag aggcgggcgc
     3301 cgtcggcgtt gcggcaggtg gccaccgagc tgacgtggat gcgcagcccc ggcacggcct
     3361 cggccagcgc caggatcagg cccgggtcgc tcgcgatcac tgcatcgccc ccaatgtcgg
     3421 catagccgca cgcgatctcg agcgcgaact cgatctgctc gaccgaatac tgctgcgcgt
     3481 tgagcaccag tgagagctgc acgccatggc ggtgggcgag ttccaccgcc tcggcgagca
     3541 cagccagcga gggcagattg ccgccggggc ggcggttggc gctggcgccg ccgaagcgct
     3601 cggcccactc gcgcggcgtc accccgcagt agagctcgtc cgcgccggca cgcgccagcg
     3661 cggcgatctc gtcgagttgc cggatggggg cgacgatctt catgcgggtc tcctcacaag
     3721 gcctcgccgg gcacgatcag gcgcgccacc cggcccgcgg ccacggccgc ggcgagcacg
     3781 gcgaggctcg ccgcggagtg gcggcagaac acggtgttgc cgacgtgcag ggtctcccag
     3841 gcgtcatgcg tgccttcgcg cgcacgctcg gtgcgggcag ctaggccgag gcactcgtga
     3901 tggcagaagg gccgcggtgc gaaacgctcc ggcccggggc gcgcgagccc ggcggtgcgg
     3961 cacatgcgcc ccttggcgac gaatgcgaag ggaaggtgca cgccgagcgg cagtggcacg
     4021 ccggcgaagc tgtcggcgcc ggcgaagagc ggcatgtcca tctcgacccg cgtgatcccc
     4081 atgcgggcga acaggcgctg ctgccagggc gaggcgaagc cgtgggcggc gggcggggcg
     4141 tactgcgggt tgcccaggcg cgggtccttg agcatgcggc acaggatgcg accggcgacc
     4201 gcctgcagca ggggatggcg ttcgtgcagg cgcagcgcca cgccccagtc gttgaccacc
     4261 acctccgcgc ccgcgggcag cagggcgaag agtggttcga gtgcacgcag gacctccggc
     4321 gaggcgaccg gcgtgagcag gcagaccgcc agcccggccg ccgacgcctc ggcgagcgtg
     4381 cgttcgagct gctccggttc gggcagcagg cgctcgcaga actcgctgcc cacgtgcagc
     4441 cgcgtcgggc gcagcggcgc cagccagtcg gcgagtgcct ggtcgtgcag ggtggcggac
     4501 cagaacgccg cgcgcgccgg aggaccggcg cacagccgat ccagcgcacg cggtcgcacc
     4561 atcgacaccg cgatcgccac cccgctcgcc ggcagcgcgg ccagggcggt gggcgacgcc
     4621 gcgctcacgc ctgtgggcgg tgacgcgggc ggacggcgca ggaaggtgag cggagcggac
     4681 attcaggagg tcgggagatt gatgttgagc agctgcgggc gggtgtattc gagcaggccc
     4741 tcgaggccga actcgacccc gaagcccgac atcttgcagc cgccgaacgg gcagtgcggc
     4801 aagacctcgg cgtggccgtt gatccacacc gtgccgcact ccaggcggtt cgccaccgcg
     4861 cgcgcggcct ccgggtcgcc cgaccacacc gagccgccga ggccgttcgt gctggcgttg
     4921 gcgagccgta ccgcctcgtc cacgtcgcgg tagcggatca ccggtagcac cgggccgaac
     4981 tgctcctcgt cgaccagccg ggtgccgtcg gcgatgtctg cgacgatggt cggcgggtag
     5041 aagtagccct tgccgggcag cggctcgccg ccgcacagga tgcgggcacc agccgcgcgc
     5101 gcgtcctcga cgagctcgca cacgcgctcg aactggtcgc ggttctggat cggcccgaag
     5161 ctcgtgccct cgtccaggcc gttgcccacc ttctgccgcg cggcgatggc caccagatgg
     5221 cggcacatgt cctcgtactg cgactcgtgc acgtagaggc gcttgagcgc ggcgcaggtc
     5281 tgtcccatgt tgaggaaggc gctgccgaac accccctcgg cgatcgcgcc gatgtcggtt
     5341 ccgggcagca cgatcccggc gtcgttgccg ccgagctcca gggtgaggcg cttcagcgtg
     5401 tcggcggcgt tgcgcatgat gtcctggccg gtgcgcgtcg agccggtgaa cacgatcttc
     5461 tggatgccac gatggccgga gatctcgcgc ccgagcgcgc cgccgccggc gaccgcgttc
     5521 accagcccgg gtggcgccac ctcgtcgatc agttcgacca ggcgcagggt gttcagcggc
     5581 gtcagctcgg agggcttgat caccaccgcg ttgcccgcgc gcagcgcggg catgatgtgc
     5641 cataccgcga tcatcagcgg ccagttccac ggcgtgattg agcccaccac gccgagcggg
     5701 cggcggtgca gctcgatgcg cttgccgggg cggtcctcga tcacctcgac cggcagctcg
     5761 agtgcggcgg tggcgcgcgt ccacgcgacc gcgccgccga cctccatatg cgcgagcgca
     5821 agcggcttgc cctgctcgcg gacgatgatc tctgcgagct cgggcgcgtt ctgctcgatg
     5881 cgtgcggcga tcgcctcgag cagggctcga cgttcctcgc acgtgctgtg ctgccactgc
     5941 tcgaatgccc gcccggctgc tgccaccgcc gcgtttagct gtgcggggga cgcgttcggg
     6001 cactcggcga aggcctcgcc gagcgcgggg tcgatgaccg gcagggtgcc gcggtctccg
     6061 gcgaccttgc ggccgtcgat gacgagggag ggcgtcttgt tcatggatcg gatcctggca
     6121 ggagttggaa ggcgtggtga cgggctcgaa gcggcagcgc cgacgccgtc acggccggca
     6181 tccgggaggg aggagaccgg atgccggccg gcgtcgaaaa ggctcggaca gcagtgcgcc
     6241 ggtcgccgtc gcggcacccc gagcgtcggg caagcgcatc catgatgcgc acgctccttg
     6301 cgctcgggac gggcttgcgg gtccgcaggc cgtgccctgc ctccgtggat ggagagacta
     6361 gccgcgcgct gtaaaccagc tttccaggat ttgtgcggaa ttgtgcgcag ttgtagcgcc
     6421 cgcagcgggg atgcgaacgg gttcagcggg ctgcggcgtc gaccgctgtt tccgcgtcct
     6481 gcggcttgaa cgtgcgcagg gccgtgaggc tgtcctcgaa cagcgtctgc agcgcagcgg
     6541 cctgtgcccg caggtccgcc cgcacgtcgt ccccggcggc cggagacacg agc
//
LOCUS       DAOTIN010000160         6496 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_14110_length_6496_cov_8.700978, whole genome shotgun sequence.
ACCESSION   DAOTIN010000160 DAOTIN010000000
VERSION     DAOTIN010000160.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 6496)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 6496)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6496
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_14110_length_6496_cov_8.700978"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..350)
                     /locus_tag="P5537_15530"
     CDS             complement(<1..350)
                     /locus_tag="P5537_15530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HRV79499.1"
                     /translation="MLVAANITQQFGAKPLFENVSVKFGDGNRYGLIGANGAGKSTFM
                     KILCGILDPSAGNVSKDPHERMAYLRQDQFAYEDMRVLDVVMMGHEELWAAIKERDAI
                     YANPDATEDDYMHAA"
     gene            614..1027
                     /locus_tag="P5537_15535"
     CDS             614..1027
                     /locus_tag="P5537_15535"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV79500.1"
                     /translation="MNAPNPASPATTERILVADDNREIADLLAELLASLGHAVDTRYD
                     GAQARAAIEAAPPRCAILDISMPGLDGCALARWVRARPDGAKIRLVAMTGHCAADERA
                     RILAAGFDEVLAKPFDLDRLEAALCGAPLCRSAAA"
     gene            1024..>1627
                     /locus_tag="P5537_15540"
     CDS             1024..>1627
                     /locus_tag="P5537_15540"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79501.1"
                     /translation="MTPGDGALADATLLAVLRRAASPLRHDMAGALLVPRMRLQMLRR
                     RAGTGALAGAELQAGVDEAIAALDAVRAAQRTAMAWFEQYDEHMLALGDALAHAASAL
                     GLAAGERGLRIDWRGGSASALAMPAQPLGLMLYAGFFHALDHAPSGASIVVACGMEEI
                     ETARVGAHGAGLANASAAAPGVCVAWRYEAERAPAGPPAEG"
     assembly_gap    1628..1727
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            1866..2969
                     /locus_tag="P5537_15545"
     CDS             1866..2969
                     /locus_tag="P5537_15545"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HRV79502.1"
                     /translation="MIPQRILLVSAAPQPLADLLAGVGRDFVLAASPDAALASLAAAP
                     CALALIEEGGAVDGPALIRSLRACEPAPACVLLMHADDASRQLDAWQAGADDCLVAPI
                     DLRLLACRIDRLLATLAARLRLEERYAELDEALRNAELLGAVLGHDLRNPLAAIATGA
                     ELLLRNPDADVVRRTAERMRTSAQRMAGMIERLLEVARSRAEPGRTRFERIDLGALAR
                     RIADEFVRPEHVGRVDLRLAGALDIDADAGSLGQALSNLVGNALKHGEAGGRVTLGVD
                     GSAADTLSITVHNPGCIAGGVVERVTEAFVRREGSQGLGLGLHIVTQIAALHGGRLGL
                     QSAEGAGTTATLVLPRRREAGVSESSDKGLGAG"
     gene            3064..3228
                     /locus_tag="P5537_15550"
     CDS             3064..3228
                     /locus_tag="P5537_15550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002925996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1328 domain-containing protein"
                     /protein_id="HRV79503.1"
                     /translation="MLRYAVIFFVIALIAAVLGFGGIAAGAADIAKLLFVVFLVLAVL
                     SFVVNLVKGK"
     gene            3353..3988
                     /locus_tag="P5537_15555"
     CDS             3353..3988
                     /locus_tag="P5537_15555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HRV79504.1"
                     /translation="MLRIAIVDDHQIVRAGFREMLADELDFEFAFEAATGEEALAGLR
                     AHDTDVLLLDLSLPGQSGVDVLRAARQRHDRLRILVLSGFPEERYALSMIRNGADGYL
                     CKDCTREELVGAIRTVAQGRRYLSPRTAELLAQELTGESTAAAHEKLSDRELQVFLRL
                     ARGESVSDIGGALHLSVKTISTYRSRLLEKLGVASNAELATYALRHGLILE"
     gene            4003..4401
                     /locus_tag="P5537_15560"
     CDS             4003..4401
                     /locus_tag="P5537_15560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV79505.1"
                     /translation="MGTSTGTPLRVVLIEDSPILRDMLRELLDELDGVQVVADADDEA
                     GALAELERHRADLAIVDLELRAGSGLGVLDRLHAEPARYGHPRAVVLSNYGHGTVRAR
                     CHACGVEHFFDKSFQMDELLDFVQAQAARH"
     gene            complement(4418..5785)
                     /locus_tag="P5537_15565"
     CDS             complement(4418..5785)
                     /locus_tag="P5537_15565"
                     /inference="COORDINATES: protein motif:HMM:NF017077.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHASE3 domain-containing protein"
                     /protein_id="HRV79506.1"
                     /translation="MPSASSTTPSRPSTPVLLAVLALVFVLGVGWILHGQRQTEAAHA
                     ALEELEAHSAQFTRLDALLLQVLEAESGARAYVLSGDEHYLSAYIDGRAQAGDTLAAL
                     RTGFAADPGALAAVDALAEPVERRWLSLDQLVAGRGSGSVEAATLIAGSAITTDIRAR
                     IEALRAPVRTRIEGITRASFERSGQARGINSVLGVAIIALLLVIGGLAWRQEELRGRI
                     TALLRTENARLQAEVDARTAELTSLAGYLSETREAEHARLAAELHDEFGPLLSAVRMD
                     AVWITRKLPAEALEPVRGRFDHLLDTLGRVVSSKRRIVAGLKPPLLADLGLAEALRSL
                     IAEMQDLKGAEVVFDAPEALPPLAQPVALALYRIAQEAIHNARRHAGAQRIAVTLAPA
                     GEEILIGVSDDGAGFDPAQVRAKGHGLAGLALRARLLGGRLEIDSARGRGTRIEARVP
                     LQPAG"
     gene            complement(5951..6262)
                     /locus_tag="P5537_15570"
     CDS             complement(5951..6262)
                     /locus_tag="P5537_15570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BON domain-containing protein"
                     /protein_id="HRV79507.1"
                     /translation="MKHTAATLALSGLLAFTAVGCAVTRDQSTVGEYVDDATVTTRVK
                     AKFAEDPTVSAMSISVETLKGTVQLSGFAKSTAERNRAGEIARSTPGVKAVKNDIAIR
                     P"
BASE COUNT          839 a         2309 c         2293 g          955 t
ORIGIN      
        1 gcggcgtgca tgtagtcgtc ctcggtggcg tccgggttgg cgtagatcgc gtcgcgctcc
       61 ttgatcgccg cccacagctc ctcgtggccc atcatcacca cgtccagcac gcgcatgtct
      121 tcatacgcga actggtcctg gcgcaggtag gccatgcgct cgtgcgggtc cttggagacg
      181 ttgcctgcgc tggggtcgag gatgccgcac aggatcttca tgaacgtcga cttgccggcg
      241 ccgttggccc cgatcaggcc gtagcggttg ccgtcgccga acttgacgga gacgttctcg
      301 aacaggggct tggccccgaa ctgctgggtg atgttggctg cgacgagcac ggaagcgtcc
      361 tgaaaattag ataaaacaaa gccttggatt atagcgcagg cacgcttgcg tgcgtcgcgc
      421 atggccccgc gacgcctgcg cgtcgggcag cgtgctcgcg cccccaggcg ccacacaaag
      481 agcgattcgc attcaggaaa tgcccgaggc atccggaaag tgtcagaatg gaccatgtgc
      541 ccgggctggg gcacggtccg catgcctgcg tgccgcggca cgaaggctcg gcatcgaacc
      601 gcaaggaatc catttgaacg caccgaaccc cgcctcgccg gccacgacag agcgcatcct
      661 cgtcgccgac gacaaccgcg agatcgccga tctgctcgcg gagctgctcg cgagcctcgg
      721 tcacgcggtc gatacccgct acgacggcgc acaggcgcgc gctgcgatcg aggcggcgcc
      781 gccacggtgc gcgatcctcg acatctccat gcccggtctc gacggctgcg cgctcgcgcg
      841 ctgggtgcgc gcccgcccgg acggcgcgaa gatccgcctc gttgccatga ccggccactg
      901 cgcggcggac gagcgcgcgc gcatcctcgc cgccggcttc gacgaggtgc tcgccaagcc
      961 cttcgatctc gaccgcctcg aggcggccct gtgcggagcg ccgctgtgcc ggagcgccgc
     1021 cgcatgactc ccggcgatgg cgcgctcgcc gatgccaccc tgctcgccgt gctgcggcgc
     1081 gcggcctcgc cgctgcgcca cgacatggcc ggcgccctgc tggtgccgcg catgcgcctg
     1141 cagatgctgc gccgccgggc gggcacaggc gcgctcgccg gagcggagct gcaggccggg
     1201 gtggacgagg cgatcgccgc gctcgatgcg gttcgtgccg cgcagcgcac cgccatggcc
     1261 tggttcgagc agtacgacga gcacatgctc gcgctcggcg atgccctcgc gcatgccgcg
     1321 tccgcgctcg gtctcgccgc cggcgagcgg ggcctgcgca tcgactggcg cggtggttcg
     1381 gcgagcgccc ttgcgatgcc cgcgcagccg cttggcctga tgctgtacgc cggcttcttc
     1441 catgcgctcg atcatgcccc cagcggcgcc tcgatcgtgg tggcgtgcgg catggaggaa
     1501 atcgagacgg ccagggtggg ggcgcacggc gccgggctgg cgaatgcctc cgcggcagcg
     1561 cccggcgtgt gcgtggcgtg gcgctacgaa gccgagcgcg cgccggcggg cccgccggcg
     1621 gaaggggnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnncgg aggggacgcc
     1741 gccggcgcgg cggcaatcgc cattccgccg cttcgtgccg aagccgtcgc cgcgctgtgc
     1801 gcgcgccatg gcgcgcgctt cgaggccacc gccgcgggcg cgagcctgca cctcgaggcc
     1861 cgcccgtgat cccgcagcgc atcctgctcg tgtccgcggc gccgcagccg ctggccgacc
     1921 tgcttgccgg cgtcgggcgc gacttcgtcc tcgccgcctc gccagacgcg gcgctcgcca
     1981 gcctcgccgc cgcgccgtgc gcgttggcgc tgatcgagga gggcggcgcg gtggacggcc
     2041 cggcgctcat ccgcagcctg cgcgcttgtg agcccgcgcc tgcgtgcgtg ctgctcatgc
     2101 atgcggacga cgccagccgc cagctcgatg cctggcaggc cggcgccgac gactgcctgg
     2161 tcgcgccgat cgacctgcgc ctgctcgcct gccgtatcga ccgtttgctc gcgacgctcg
     2221 ctgcccgcct gcggctggag gagcgctatg ccgaactcga cgaggcgctg cgcaatgccg
     2281 agctcctcgg tgcggtcctc ggccacgacc tgcgcaatcc gctcgctgcg atcgccaccg
     2341 gcgccgagct gctgctgcgc aacccggatg cggacgttgt gcggcgcacg gcggagcgca
     2401 tgcgcaccag cgcgcagcgc atggccggca tgatcgagcg cctgctcgag gtggcgcgct
     2461 cgcgtgccga acccggacgc acacgcttcg agcgcatcga cctcggcgcg ctggcgcggc
     2521 ggatcgcgga cgagttcgtc cgccccgaac acgtcggccg cgtcgatctg cggctcgcgg
     2581 gcgcgctcga catcgacgcc gacgccgggt cgctcggcca ggcgttgtcc aatctggtgg
     2641 gcaacgcgct caagcacggc gaggccggcg gcagggtcac gcttggcgtg gacggcagcg
     2701 cggccgatac gctctccatc acggtgcaca acccgggctg cattgccggc ggggtcgtcg
     2761 agcgcgtgac cgaggccttc gtccgtcgcg agggcagcca gggcctgggg ctcgggctcc
     2821 acatcgtcac ccagattgcg gccctccatg gcggccgcct cggcctgcag agcgctgagg
     2881 gcgcgggcac gacggccacg ctggtgctgc cgcggcggcg cgaggccggc gtgtcggaat
     2941 cgtccgacaa gggtttaggt gcgggctgat ggagaccgcg gcggcggcgg cctagagtgg
     3001 aaccgtgagc cgaacggcac gaccgccaga gccttcgcca cccccgatcc caaggagtcc
     3061 atcatgctgc gctacgccgt catcttcttc gtcatcgccc tcatcgccgc cgtgctcggt
     3121 tttggcggca tcgccgccgg tgccgcggac atcgccaagc tgctcttcgt cgtcttcctc
     3181 gtgctcgcgg tgctgagctt cgtggtcaat ctcgtgaagg gcaaatgacg ctgcctcccc
     3241 gaccggccgc cgcgacgcgc gacggcccgc tcacccgccc cggctgccct cgttcgcgag
     3301 cggcggccgg gcgggcgttc acctccactc cgactttcgc aggctgaagg ccatgctcag
     3361 gattgcaatc gtcgacgacc accagatcgt gcgcgcgggc ttccgcgaga tgctcgcgga
     3421 cgagctcgac ttcgagttcg ccttcgaggc cgccaccggc gaggaggcgc tcgccggcct
     3481 gcgcgcgcac gacaccgacg tgctgctgct cgacctctcg ctgcccgggc agagcggcgt
     3541 ggacgtgctg cgcgccgcgc gccagcgcca cgaccggctg cgcatcctgg tgctctcggg
     3601 ctttcccgag gagcgctacg cgctgtcgat gatccgcaac ggcgccgacg gctacctgtg
     3661 caaggactgc acccgcgagg agctcgtcgg tgcgatccgc accgtcgccc aggggcggcg
     3721 ctacctgtcg ccgcgtaccg cggagctgct cgcccaggag ctcaccggcg agagcaccgc
     3781 cgccgcccac gagaagctgt ccgaccgcga gctgcaggtc ttcctgcgcc tggcgcgcgg
     3841 cgagtcggtg tccgacatcg gcggcgccct gcacctgagc gtcaagacca tcagcaccta
     3901 ccgttcgcgc ctgctcgaga agctcggcgt ggccagcaac gccgaactcg ccacctacgc
     3961 cctgcgccac gggctgatcc tggaatgagg acggaggcgg gcatgggcac atcgaccggg
     4021 acgccgctgc gcgtggtgct gatcgaggac tcgccgatcc tgcgcgacat gctgcgcgag
     4081 ctgctcgacg agctcgacgg cgtgcaggtg gtggccgacg ccgacgacga ggcgggtgcg
     4141 ctcgccgagc tcgagcgcca ccgcgcggat ctcgccatcg tcgacctcga gctgcgcgcc
     4201 ggcagcggcc tcggcgtgct cgatcgcctg cacgccgaac ccgcgcgcta cggccacccg
     4261 cgcgccgtgg tgctgtccaa ctacggccac ggcacggtgc gcgcgcgctg ccatgcctgc
     4321 ggcgtcgagc atttcttcga caaatccttc cagatggacg agctgctcga cttcgtgcag
     4381 gcgcaggccg cgcggcactg atcgccggcc gccggcctca gcctgcgggc tgcagcggca
     4441 cccgcgcctc gatccgcgtc ccgcgcccgc gcgcgctgtc gatctcgagg cggccgccga
     4501 gcagccgtgc ccgcagggcc aatccggcga ggccgtggcc cttcgcgcgc acctgtgccg
     4561 gatcgaagcc ggcgccgtcg tcgctcacac cgatcaagat ctcttcgccc gcgggggcga
     4621 gcgtcaccgc gatgcgctgc gcgccggcgt ggcggcgggc gttgtggatc gcctcctggg
     4681 cgatgcggta gagcgccagc gccaccggct gcgcaagcgg cggcagcgcc tcgggagcgt
     4741 cgaacacgac ctccgcgccc ttgaggtcct gcatctcggc gatcagcgaa cgcaaggctt
     4801 cggcgagccc gaggtcggcg agcagcggcg gcttgaggcc ggcgacgatg cggcgcttgc
     4861 tcgacaccac cctgccgagg gtgtcgagca ggtggtcgaa gcggccgcgc accggctcca
     4921 gggcctcggc gggcagcttg cgggtgatcc acaccgcatc catgcgcacc gccgacagca
     4981 gcgggccgaa ctcgtcgtgc agctcggccg cgaggcgggc gtgctccgcc tcgcgggttt
     5041 cgctcaggta gccggcgagg ctggtcagct cggcggtgcg ggcgtcgacc tcggcctgca
     5101 ggcgggcgtt ttccgtacgc agcagggcgg tgatgcggcc gcgcagctcc tcctggcgcc
     5161 aggcgagccc gccgatcacc agcagcaagg cgatgatcgc gacgccgagc accgaattga
     5221 tcccgcgcgc ctggcccgag cgctcgaagg acgcgcgcgt gatgccctct atgcgtgtgc
     5281 gcaccggcgc gcgcagcgcc tcgatgcgtg cgcggatgtc ggtggtgatc gcggagccgg
     5341 cgatcagggt cgcggcctcg acgctgccgc tgccgcgccc ggcgacgagc tggtcgagcg
     5401 agagccagcg ccgctccacc ggttcggcga gcgcatccac cgcggcgagc gcgccggggt
     5461 cggcggcgaa gccggtgcgc agcgccgcga gcgtgtcgcc ggcctgggcg cgaccgtcga
     5521 tgtaggcgct caggtagtgc tcgtccccgc tcaatacata ggcgcgtgcg cccgactccg
     5581 cctccagcac ctgcagcagc agggcgtcga ggcgggtgaa ctgggcggag tgggcctcga
     5641 gctcttcgag cgcggcgtgc gcggcctcgg tctggcgctg tccatggagg atccagccca
     5701 ccccgagcac gaacacgagc gccagcaccg ccagcaacac gggcgtggac ggtcggctcg
     5761 gtgtggtgga ggacgcggaa ggcatggctc gacgggtagg cgatgaagtt tggcgggaat
     5821 ccatttagcc acggttttcc gggcgcggcc gtgcattgct tccgcccgcg cgcgaatcct
     5881 tccgggctcg gggctgtgaa cggccgaagg gggctcgcgc ccccttcgct ggccgatgct
     5941 cccgcgacgc ttacgggcgg atcgcgatgt cgttcttcac cgccttcacc cccggcgtgc
     6001 tgcgggcgat ctcgccggcg cggttgcgct cggcggtgct cttggcgaag ccggacagct
     6061 gcaccgtgcc cttgagcgtc tccacgctga tcgacatggc gctgacggtc ggatcctcgg
     6121 cgaacttggc cttcacccga gtggtgacgg tggcgtcatc gacgtattcg cccacggtgg
     6181 actggtcgcg ggtgacggcg cagccgaccg cggtgaaggc gagcaggccg gagagggcga
     6241 gagtggcggc ggtgtgcttc atggtgggtc tcctgagagg tctggtgttt ttgcgggttg
     6301 gccccgcgag cgggttgcaa gctcactata ggacacggct ctcgcgggcg ctgtccgacg
     6361 aggcggaaag gcgtgtagga cgattccgtc atgccccatg tcggcggctg ttggcctcgc
     6421 gtgcccatgg cgtcaccaac tcatcccttc atcgattcct acaaatgcag acgccttcgt
     6481 cctattcagc gtgcct
//
LOCUS       DAOTIN010000161         6474 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_14182_length_6474_cov_9.278236, whole genome shotgun sequence.
ACCESSION   DAOTIN010000161 DAOTIN010000000
VERSION     DAOTIN010000161.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 6474)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 6474)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6474
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_14182_length_6474_cov_9.278236"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1165
                     /gene="amt"
                     /locus_tag="P5537_15575"
     CDS             <1..1165
                     /gene="amt"
                     /locus_tag="P5537_15575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008519 - ammonium transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HRV79508.1"
                     /translation="PGLALFYGGMVRAKNMLSVLMQVMVVFSLNALLFAIYGYSLTFT
                     EASPFIGSLDKVFLSGVTIETLADTFTETVKLPEFAFIAFQATFAGITGALIVGAFAE
                     RMKFSAVLIFSVIWFTLCYLPICHMVWGPGGYLLEDGALDFAGGTVVHINAGIAGLVG
                     AWMVGKRIGYGREALAPHSLTLTMVGASLLWVGWFGFNAGSNLEATAGAALAFINTLV
                     ATAAAVLAWSLGEALIKGKPSMLGAASGAVAGLVAITPACGSVGPMGAIVIGTLSGFI
                     CIWGVNGLKRMLGADDALDVFGVHGVGGIVGAILTGVFAAPSLGGTGAEDFSIASQVW
                     IQTWSVLVTIVWSAVVAFVAYKVADLLVGLRVPEDEERQGLDTTAHGETAYRY"
     gene            1355..2134
                     /locus_tag="P5537_15580"
     CDS             1355..2134
                     /locus_tag="P5537_15580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4239 domain-containing protein"
                     /protein_id="HRV79509.1"
                     /translation="MLFSDWHSYDHYGLAFVAFFGTLAAVFLIQWVMMRSRWAGWMQS
                     LQGVAPPFMNALGVLFGLVLAFLANDTWSAHDRAMSAVYREADGLRSIGALAATVPEP
                     LGSELRTAAAAYARASAAEWTELARRREAPEVLARADALLALLAAPAVAEAAGTNVQA
                     LLLRKASDIRADHDLRVALSQTHVNPLKWLGMAFLGFLTLVSVAMAHLERPRAAFAAV
                     LLFALAAAPTAAIVLIQGNPFQQPSSVTAAPITAVAKALER"
     gene            complement(2168..2512)
                     /locus_tag="P5537_15585"
     CDS             complement(2168..2512)
                     /locus_tag="P5537_15585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HRV79510.1"
                     /translation="MSAELRAAGRGNLFTALPPPGGGEIFQTLFAGPGCRVERIVSHG
                     HASAPGDWYDQDGDEWVVLLAGDAVLRFERGGDVALKAGDWIAIPAHSRHRVESTSAD
                     ALWLAVHGTPSG"
     gene            complement(2523..3014)
                     /locus_tag="P5537_15590"
     CDS             complement(2523..3014)
                     /locus_tag="P5537_15590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HRV79511.1"
                     /translation="MPKHATPPDLPVQFEPEFITGVREIFEQKIAFNALLGLQIDDIG
                     GERVHGRIAMRHELVGHFVHNRIHGGVIAACLDAMGGLAVMAAIGARHLDEPPFQRLH
                     RFSKLGTIDLRIDYLRPGIGESFRMEAEVLRLGSRVASTRMSFLDADGKLLSTGSAAY
                     IVS"
     gene            complement(3148..4548)
                     /locus_tag="P5537_15595"
     CDS             complement(3148..4548)
                     /locus_tag="P5537_15595"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HRV79512.1"
                     /translation="MISVEKIGGTSMSAFGDVLRHIMLYDKARILGRIYVVSAYSGVT
                     NQLLEHKKTGERGIYALFAEGSDYHGALDALAASLKKLNAGFAELALPLDVADAFVDT
                     RIGEVKKYLDAMQHVLASGYIRRQDVLLAAREVLASVGESHSAFNSVEMLKANGVNAI
                     LLDLAGFHDDKAWTIDERIHNSFKGLDLDNSVIVATGYTKGTEGIMREFDRGYSEVTF
                     SKIAVEVRPAEAVIHKEFHLSSADPNIVGLENAVIVGATNYDVADQLADVGMEAIHPK
                     AAKPMELAGIPIRLKNTFEPDHPGTLITKDYVGERARVEMVTGSDKVTLVEIHDPSMV
                     GTVGFDLGIMEIFFKHDVSYILKATNANSIAHVLWESSVTPELVAELEARYQVVTVKN
                     SAIVCAIGSNISIPGVLARAAQALADAQINVNCVSQTLRQVNMQFIIERSDYKQAIIA
                     LNHSLCVTPGVPVPRA"
     gene            complement(4750..5838)
                     /locus_tag="P5537_15600"
     CDS             complement(4750..5838)
                     /locus_tag="P5537_15600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase"
                     /protein_id="HRV79513.1"
                     /translation="MSAPAARRLNTQYLSAERVAEIVRRKGLANCIAGVASYIRQDFL
                     RWNDFDKCARVASHSEVGVIELMPVSDARSYAFKYVNGHPSNHRFRLPTVMAFGVLAD
                     VETGTPELVSELTLTTAIRTAAMSAVAARALAREDVRSMALIGNGAQSEFQALAFHHL
                     LGVEVFHLFDVDTAATRKLAANLERLGLAWRAFDSVGAAVRGCDIVTTATADKTNAAI
                     LTADIIEPGMHLNAVGGDCPGKTELHADVLRLGPVFCEFEPQSRIEGDMQQMPADFPV
                     TELWQVLAGRVQGRTSAAQVTIFDSVGFALEDYSALRYMRDLALESGMGERLALIPEL
                     DDPKDLFGFIAAEPPVAAASGAATVAAC"
     gene            5983..6405
                     /locus_tag="P5537_15605"
     CDS             5983..6405
                     /locus_tag="P5537_15605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HRV79514.1"
                     /translation="MDTLDHQLIGLLRNDARLSVAALAHKLQVSRGTVTNRIARLEDQ
                     GIIVGYTVRLRPDAQPNEIRAWTSIAVEGNETRMVIASLLGEPAVAELHDTNGRWDLL
                     VGLRAANLTELSTVLERIRLIKGIHSSETSIHLKTYRV"
BASE COUNT          979 a         2232 c         2203 g         1060 t
ORIGIN      
        1 gcccggcctg gcgctgttct acggcggcat ggtgcgcgcc aagaacatgc tctcggtgct
       61 gatgcaggtg atggtcgtgt tctcgctcaa cgcgctgctg ttcgcgatct acggctacag
      121 cctgaccttc accgaagcca gccccttcat cggctcgctc gacaaggtct tcctgtccgg
      181 ggtgacgatc gagacgctcg ccgacacctt caccgagacc gtgaagctgc ccgagttcgc
      241 cttcatcgcc ttccaggcca ccttcgcggg catcaccggc gcgctgatcg tgggcgcctt
      301 cgccgaacgc atgaagttct ccgccgtgct gatcttctcg gtgatctggt tcacgctgtg
      361 ctacctgccg atctgccaca tggtgtgggg cccgggcggc tacctgctcg aggacggcgc
      421 gctcgacttc gccggcggca ccgtggtgca catcaacgcc ggcatcgccg gcctggtggg
      481 cgcctggatg gtgggcaagc gcatcggcta cggccgcgag gcgctcgcgc cgcacagcct
      541 gaccctgacc atggtcggcg cctcgctgct gtgggtgggc tggttcggct tcaacgccgg
      601 ctccaacctc gaggccaccg ccggcgccgc gctcgccttc atcaacaccc tggtcgccac
      661 cgctgccgcg gtgctggcgt ggtcgctcgg cgaagcgctg atcaagggca agccctcgat
      721 gctgggcgcg gcctcgggcg cggtcgccgg cctggtggcg atcaccccgg cctgcggttc
      781 ggtgggcccg atgggtgcga tcgtgatcgg cacgctgtcc ggcttcatct gcatctgggg
      841 cgtgaatggc ctcaagcgca tgctcggcgc ggacgacgca ctcgacgtgt tcggcgtgca
      901 tggcgtgggc ggcatcgtcg gcgcgatcct gaccggcgtg ttcgccgcac ccagcctggg
      961 cggcaccggc gcggaggact tctcgatcgc ctcgcaggtg tggatccaga cctggagcgt
     1021 gctcgtgacc atcgtgtggt cggccgtcgt cgccttcgtc gcctacaagg tcgcggacct
     1081 gctggtcggg ctgcgcgtgc cggaagacga ggagcgccag ggcctcgaca ccacggcgca
     1141 cggcgagacc gcctaccgct actgagcagc cctctcccgg aaccgtcctc ctccggttcc
     1201 gatccactcg cggcgcccct cggggcgccg ttttttctgt ggcgcgcagg acgcgcgagc
     1261 atccggcgcg gccccggggc gggcggcccg ggcatcgggc gagcccccgg ggcggttaaa
     1321 ctgaggcctt gtcgaccgcg caagcgagcc cccgatgctc ttctccgact ggcacagcta
     1381 cgaccactac ggcctcgcct tcgtcgcctt cttcggcacc ctcgccgccg tgttcctgat
     1441 ccagtgggtg atgatgcgct cgcgctgggc gggctggatg cagtcgctgc agggggtggc
     1501 gccgccgttc atgaacgcgc tcggcgtgct cttcggcctg gtgctcgcct ttctcgccaa
     1561 cgacacctgg agcgcgcacg accgcgcgat gagcgccgtg tatcgcgagg cggacggcct
     1621 gcgcagcatc ggcgcactcg ccgccaccgt gcccgagccg ctcggcagcg agctgcgcac
     1681 ggcggcggcc gcttacgcgc gcgccagcgc cgccgaatgg acggaactcg cacgccgccg
     1741 cgaggcaccg gaggtgctcg cccgcgccga tgcgctgctg gccctacttg ccgccccggc
     1801 ggtcgccgag gccgccggca ccaacgtgca ggccctgctg ctgcgcaagg ccagcgacat
     1861 ccgcgccgat cacgacctgc gcgtggcgct cagccagacc cacgtcaacc cgctgaagtg
     1921 gctcggcatg gccttcctgg gtttcctgac cctggtctcg gtggccatgg cccacctcga
     1981 acgcccgcgt gcggcgttcg cggcggtgct gctgttcgcc ctcgccgcgg cccccaccgc
     2041 cgccatcgtg ctgatccagg gcaacccctt ccagcagccg agctcggtca ccgcggcacc
     2101 gatcacggcg gtcgccaagg cattggagcg ctgaggcgca gtgcctccgg gagcgcgcgg
     2161 cgccgtctca gccgctgggc gtaccgtgca ccgccagcca tagcgcgtcc gccgaggtcg
     2221 actcgacgcg gtgccgggaa tgcgccggga tggcgatcca gtcgcccgcc ttcaaggcca
     2281 cgtcgccacc cctctcgaag cgcagcaccg catcgccggc cagcaggacc acccactcgt
     2341 cgccgtcctg gtcgtaccag tcgcccggag cgctcgcatg gccgtgcgag acgatgcgtt
     2401 cgacacggca gcctggaccg gcgaacaggg tctggaagat ctcgccaccg ccgggcggag
     2461 gcagcgccgt gaagagattg ccgcgccccg cggcccgaag ctcggcgctc attccccgcc
     2521 gctcacgaga cgatgtacgc cgccgaaccg gtggacagca gcttgccgtc ggcgtcgagg
     2581 aagctcatcc gcgtcgatgc gacgcgcgag cccaggcgca ggacctcggc ctccatgcgg
     2641 aaggactcgc cgatgccggg gcgcaggtag tcgatgcgca ggtcgatggt gccgagcttg
     2701 gagaagcggt gcaggcgctg gaagggcggc tcgtcgaggt ggcgggcgcc gatcgccgcc
     2761 atcaccgcca gcccgcccat ggcgtcgagg caggcggcga tcacgccgcc atggatgcgg
     2821 ttatgaacga aatggccgac gagctcgtgg cgcatcgcga tgcggccatg cacgcgctcg
     2881 ccgccgatgt cgtcgatctg caggccgagc agcgcattga aggcgatctt ctgctcgaag
     2941 atctcacgga caccggtgat gaactccggc tcgaactgca ccggcagatc cggcggggtg
     3001 gcgtgtttcg gcatggatgc aagctccctt gcgagaaatg gcacagcccc gggcgtgacg
     3061 gacacgcgcc ggggccgtgg acagtcttgc gggcgcggac tgtatgcccg caagactgtt
     3121 gcgccctgcg ggggcgcgac ggaaggatca ggcgcgcggc accggcacgc cgggcgtcac
     3181 gcacagcgaa tggttgaggg cgatgatcgc ctgcttgtag tcgctgcgct cgatgatgaa
     3241 ctgcatgttc acctggcgca gggtctgcga cacgcagttc acgttgatct gcgcgtcggc
     3301 gagcgcctgc gccgcgcgcg cgagcacgcc ggggatgctg atgttggaac cgatcgcgca
     3361 cacgatcgcg ctgttcttga ccgtgaccac ctggtagcgc gcctccagct cggcgaccag
     3421 ctcgggcgtc accgagctct cccacagcac gtgggcgatc gagttggcgt tggtcgcctt
     3481 gaggatgtag gagacgtcgt gcttgaagaa gatctccatg atcccgagat cgaagccgac
     3541 ggtgccgacc atgctggggt cgtggatctc gaccagagtg accttgtcgc tgccggtcac
     3601 catctcgacg cgggcgcgct cgccgacgta gtccttggtg atcagcgtac ccgggtgatc
     3661 gggctcgaag gtgttcttga ggcggatcgg aatgccggcg agctccatcg gcttggccgc
     3721 cttggggtgg atggcctcca tgccgacgtc ggcgagctgg tcggcgacgt cgtagttggt
     3781 cgcacccacg atcaccgcgt tctccaggcc gacgatgttg gggtcggccg aggagaggtg
     3841 gaactccttg tggatcaccg cctcggcggg gcgcacctcg accgcgatct tgctgaaggt
     3901 gacctcggaa tagccgcggt cgaactcgcg catgatgccc tcggtgccct tggtgtagcc
     3961 ggtcgcgacg atcacgctgt tgtcgaggtc gaggcccttg aagctgttgt ggatgcgctc
     4021 gtcgatcgtc cacgccttgt cgtcgtggaa gccggcgagg tcgagcagga tggcattgac
     4081 gccgttggcc ttgagcatct ccacgctgtt gaaggcgctg tgcgactcgc ccaccgaggc
     4141 cagcacctcg cgcgcggcga gcagcacgtc ctggcggcgg atgtagccgc tggcgagcac
     4201 gtgctgcatc gcgtcgagat acttcttgac ctcgccgatg cgggtgtcga cgaaggcgtc
     4261 ggcgacatcc agcggcaggg cgagctcggc gaagccggcg ttgagcttct tgaggctggc
     4321 cgcaagcgcg tcgagcgcgc cgtggtagtc cgaaccttcc gcgaacagcg cgtagatgcc
     4381 gcgctcgccg gtcttcttgt gctccagcag ctggttggtc acgccggaat aggccgacac
     4441 cacgtagatg cggccgagga tgcgcgcctt gtcgtagagc atgatgtggc gcagcacatc
     4501 cccgaaggcc gacatcgagg tgccaccgat cttttcaacc gagatcatcc gttttcccga
     4561 gctttgcatg acgtgtattc cagttctgat tagagaccga ccgaaacccg tcatcgtatt
     4621 gttttggcgc ggaaatggac atagccgcgg acgaaatcgg cgccacttcg gcgcgatttt
     4681 ctcgtccagg ccaccagaaa cgctgcccgc gggcgactgc gcccggaacc gagccgccct
     4741 ccgacgggct cagcaggcag ccaccgtcgc cgcgcccgat gcagccgcaa cgggcggctc
     4801 cgcggcgatg aagccgaaca ggtccttcgg atcgtccagc tccgggatca gcgccagccg
     4861 ctcgcccatg cccgactcca gcgcgaggtc gcgcatgtag cgcagcgccg aatagtcctc
     4921 cagcgcaaag ccgaccgagt cgaagatcgt gacctgggcc gcgctcgtgc gcccctggac
     4981 acgaccggcg agcacctgcc agagctcggt gaccgggaaa tcggcgggca tctgctgcat
     5041 gtcgccctcg atgcgcgact gcggctcgaa ctcgcagaac accgggccga ggcgcagcac
     5101 gtcggcgtgc agctcggtct tgcccgggca gtcaccaccc acggcattga ggtgcatgcc
     5161 cggctcgatg atgtcggcgg tgaggatggc ggcgttggtc ttgtcggcgg tcgccgtggt
     5221 cacgatgtcg cagccgcgca cggccgcgcc cacgctgtcg aaggcgcgcc aggccaggcc
     5281 caggcgctcg aggttggcgg cgagcttgcg ggtggcggcg gtgtcgacgt cgaacagatg
     5341 gaagacctcg acgcccagca ggtggtggaa ggcgagcgcc tgaaactcgc tctgcgcgcc
     5401 gttgccgatc agcgccatgc tgcgcacgtc ctcgcgcgcc agcgcccgtg cggccaccgc
     5461 cgacatcgcg gcggtgcgga tcgcggtggt cagggtcagc tcgctgacca gctcgggggt
     5521 gccggtctcg acgtccgcga gcacgccgaa ggccatcacg gtcggcagcc tgaagcgatg
     5581 gttcgacggg tgcccattca catacttgaa ggcatagctg cgggcgtccg acaccggcat
     5641 cagctcgatc acgccgacct cggagtggct ggcgacgcgg gcgcacttgt cgaaatcgtt
     5701 ccagcgcagg aagtcctggc ggatgtagct ggcgacgccg gcgatgcagt tggcgagccc
     5761 cttgcggcgc acgatctcgg cgacgcgctc ggcgctcagg tactgggtgt tcagacgtct
     5821 ggctgcaggg gcgctcatga tcggtctccg tcctcgttat tggatgtggc gctgtgctgg
     5881 cgtcatcttg accgaatgcg ccgccaaaca gaatccgcaa ctctgtatcg aaaacgtcag
     5941 cctttaggca gaatcgccag gccaaattgc cggaatgctc gaatggacac cctggatcac
     6001 cagttgatcg gcctgctgcg caacgacgcc cgcctgagcg tggccgcgct cgcgcacaag
     6061 ctccaggtct cgcgcggcac cgtcaccaac cgcatcgcgc gcctcgagga ccagggcatc
     6121 atcgtcggct acaccgtgcg cctgcgcccc gacgcgcagc ccaacgagat ccgcgcctgg
     6181 accagcatcg ccgtcgaagg caacgaaacc cgcatggtga tcgccagcct gctcggcgaa
     6241 cccgcggtcg ccgagctgca cgacaccaac ggccgctggg acctgctcgt cggcctgcgc
     6301 gcagccaacc tcaccgagct gtcgacggtg ctcgagcgca tccgcctgat caagggcatc
     6361 cacagcagcg agaccagcat ccacctgaag acctaccggg tgtaggccgt cgccgcggag
     6421 ctcagcggaa cacgatcgtc ttgttcccat gcaccagcac ccggtcctcc aggt
//
LOCUS       DAOTIN010000162         6373 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_14467_length_6373_cov_8.350744, whole genome shotgun sequence.
ACCESSION   DAOTIN010000162 DAOTIN010000000
VERSION     DAOTIN010000162.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 6373)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 6373)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6373
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_14467_length_6373_cov_8.350744"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(183..1145)
                     /locus_tag="P5537_15610"
     CDS             complement(183..1145)
                     /locus_tag="P5537_15610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HRV79515.1"
                     /translation="MQKIVFLDRATLAPQIRLRRPAFPHDYVEHARTTPAELVDRLAG
                     ATIAILNKVRLDAAAIAQLPTLRLVAVAATGTDCVDKAACAARGIAVCNIRGYARDTV
                     PEHVFALLLALRRQLVPYRDDVLAGEWQRAGQFCFFNHPIHDLAGTRLGIVGAGDLGQ
                     RVAAIARAFGMEPVFAARKGAQPVDDRYTAWDEVLATSDVISLHCPLTEATRGLIGLP
                     EFRAMARRPLMINTARGGIVDEHALVQALDEGLIAGAGFDVTDGEPPAPDSPLMRIAA
                     RPNVILTPHIAWASDEAQQALADQLVDVIEKFVGGEPRNLVVRG"
     gene            complement(1356..1799)
                     /locus_tag="P5537_15615"
     CDS             complement(1356..1799)
                     /locus_tag="P5537_15615"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79516.1"
                     /translation="MTPDPRNALALFKANLELQFRLCDLMRRNTLRWNEAQNRMIDGC
                     ASEFEASATRLLDAPDWQQVGFVATDLGWKSLQQRNCALLKMAEAVVANQSALQQDMQ
                     QAWAQWQHDCTRALKEASGTMPLSATFEELLATATRPALLPGGKG"
     gene            complement(1998..3962)
                     /locus_tag="P5537_15620"
     CDS             complement(1998..3962)
                     /locus_tag="P5537_15620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004375187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HRV79517.1"
                     /translation="MSPSAPKPPSRQAAPARTRRQPLNEAATGTAGKPARGARANASG
                     ASTPASSAPSATHAQTPKPLARPTAHPARSFAAPFAPPPPRNPLDRRVHAAIARATAS
                     VSPIALLLAAVDWAGHLALSPGKRMELADLGIEQTRRLLRYAQQLAVAPAGSAAHECI
                     EPPAQDRRFKAPEWHAWPFNLMHQSFLLGQEWWDAATHGVAGVSRHHEQVVAFAARQL
                     LDLFSPGNFLPTNPVVLRQTQESGGLNLVRGAIHAVEDFERLVGGAPPAGAEDFVVGR
                     DVAVTPGKVVLRNRLIELIQYAPATADVYAEPVLIVPAWIMKYYILDLSPHNSLVRYL
                     VERGHTVFCISWKNPGTDERTLDMDDYLQLGFFAALDAINAIVPGQKVHATGYCLGGT
                     LLAIAAAAMDRDGDTRLGSMTLFTAQTDFTEPGELALFIDESEVSLLEAQMEETGFLT
                     AGQMAGAFQILRSNDLLWSRIVGEYLMGERTPMNDLMAWNADATRMPARMHSQYLRRL
                     FLNDDLSEGRYPVGGKPVALSDIELPVFCVATLTDHVAPWRSVYKLHYLVPTEISFVL
                     TSGGHNAGIVSEPGRPRRSFRLRTRPAGGNYVPPDDWLERTPEQEGSWWPAWSDWLAA
                     RSGARVAPPAIGAVNYPALDDAPGRYVHEK"
     gene            complement(3986..5188)
                     /locus_tag="P5537_15625"
     CDS             complement(3986..5188)
                     /locus_tag="P5537_15625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV79518.1"
                     /translation="MARHPTPPNPPGPPPTPSPPKHTDHATHLRNIWNLGLKEFRSLS
                     RDFAMVFLIVFMFSASIYADARAKPESLSRASIAVVDEDGSQLSGRIVAALQPPQFLP
                     PEHVGLADMDRGLDAGRHTFVLDIPPNFQRDVLAGRSPALQLNIDATRQGQAQTGAGY
                     IQNIIADEVRAFVQRMRAPAPQPVELVPRAMFNPNLEASWFAAINAIINNVTMLGILL
                     TGAALIREREHGTIEHLLVMPVTPLEIMLSKIWAMGVVVLVASSFSLQVMVKGVLGIT
                     VAGSAVLFGAGTLLYLFAAASIGIYMGTIARSMPQFGLMSILVLLPLQILSGGVTPRE
                     SMPEAIQAIMALAPTTHYVSLAQAILFRGAGVDVVWPAFAMVAAIGAVFLGLAHHRLR
                     HTIGTMQN"
     gene            complement(5200..>6373)
                     /locus_tag="P5537_15630"
     CDS             complement(5200..>6373)
                     /locus_tag="P5537_15630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004375191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV79519.1"
                     /translation="GGDAPTTPTPAADRIARFSLGRLLSFSAREATELRRDPVRLTLA
                     LLGSLLLMLVMGYGITMDVEDLHYAVLDHDRSVASQSYTLRIAGSRYFLEQAPLDSHA
                     DLDARMRAGRLAMAIEIPPGFGRELARGKAPQVAVWLDGSMPLRAELARAYVGGVHAQ
                     TLADVIAESGAGPVRALATVEPRYRYNPELLSLVSMVPKVIPLLLVFIPAMLTALGVV
                     REKELGSILNVYTTPVTKLEFLLGKQLPYIALSMFNFALLFVLAVTLFQVPFKGSLLA
                     LATGALLYVAATTGLGLLASTLTNSQVAALAGTSIGTLLPAIQFSGLMDPVSALEGGG
                     YWIGAIYPTTHFLTIASGTFSKALGFADLVGSFVPLALAIPVLTLLSALLLKKQAK"
BASE COUNT          888 a         2012 c         2544 g          929 t
ORIGIN      
        1 cctcctgtag gagcgccggc aggcgcgaaa gcggcggtgg gcgccgcaac gcgcgtccag
       61 tgccgctccg cccaattcgc gcctgccggc gctcctacat gaaacccacc gtcacgaaca
      121 tcgcctcgcg cttctgcatg gagccgatcg ttccgcgacc cggcgggcct tgacgcgctt
      181 ccctagcccc tgacgacgag attcctcggc tcgccgccaa caaatttttc gatgacatcg
      241 acaagctggt cggcgagggc ctgctgggct tcgtccgagg cccaggcgat gtgcggggtg
      301 aggatgacgt tcgggcgggc ggcgatgcgc atcagcgggc tgtcgggcgc gggcggttcg
      361 ccgtcggtga cgtcgaagcc ggcgccggcg atcaggccct cgtcgagcgc ctgcaccagc
      421 gcgtgctcgt cgacgatgcc cccgcgcgcg gtgttgatca tcagcgggcg acgcgccatc
      481 gcgcggaact cgggcaggcc gatgaggccg cgggtggcct cggtgagcgg gcagtgcagg
      541 ctgatgacgt cgctggtggc gagcacttcg tcccaggccg tgtagcggtc gtcgacgggc
      601 tgcgcgccct tgcgcgcggc gaacaccggc tccatgccga aggcgcgcgc gatcgcggcg
      661 acgcgctggc cgaggtcgcc ggcgccgacg atgccgaggc gcgtgccggc gagatcgtgg
      721 atggggtggt tgaagaagca gaactgcccg gcgcgctgcc attcgccggc gaggacgtcg
      781 tcgcggtagg ggacgagctg gcggcgcagc gccagcagga gcgcgaagac gtgctcgggg
      841 acggtgtcgc gcgcgtagcc gcggatgttg cacaccgcga tcccgcgcgc ggcgcaggcg
      901 gccttgtcca cgcagtcggt accggtggcg gcgaccgcga ccaggcgcag cgtcggcagt
      961 tgcgcgatcg ccgcggcgtc gaggcggacc ttgttgagga tcgcgatggt ggcgccggcg
     1021 aggcggtcga cgagctcggc gggcgtggtg cgggcgtgtt cgacgtagtc gtgcgggaag
     1081 gcagggcggc gcaggcggat ctgcggcgcg agggtggcgc ggtcgaggaa gacgatcttt
     1141 tgcatggcgg gctctcgggg ggagcgggga ttatcgccgc gggcgggtgg gggtgaaggt
     1201 cgcgcgcgat tcgggcggtt gaggtgtcgt cgtccgcgtg taggggcgcc acgagcagcg
     1261 cccggcgccc cgtaacctcc gatgtgggag cgccggcagg cgcgaatgcg gcgctgcggc
     1321 cggcgacgcg cccggggctg gtgcgcttgc ccgggtcagc ccttgccgcc gggcagcagc
     1381 gccgggcggg tggccgtggc gaggagctcc tcgaaggtgg cgctgagcgg catcgtgccg
     1441 ctcgcttcct tgagcgcgcg ggtgcagtcg tgctgccatt gtgcccaggc ctgctgcatg
     1501 tcctgctgca gcgcggactg gttggcgacc acggcttcgg ccatcttgag cagggcgcag
     1561 ttgcgttgct gcagggactt ccagccgagg tcggtggcga cgaagcccac ctgctgccag
     1621 tcgggggcgt ccagcaggcg ggtggcggag gcctcgaatt cgctggcgca gccgtcgatc
     1681 atgcggttct gcgcctcgtt ccagcgcagc gtgttgcggc gcatgaggtc gcacaggcgg
     1741 aactgcagct cgaggttggc cttgaagagg gcgagggcgt tgcgggggtc gggggtcatc
     1801 gcggtttcct tcgggatggg atccggacaa gggcggggcc tcgtccgggc ctgctcggcg
     1861 agatcggtcg cgccgcgcgg ctgcgcatcg gttcgcgggt gtcggagagg cttcgcccgg
     1921 gagggctccc gcatcgcccg atcggcgctg cgcgatgcga actccccgag acccgggagc
     1981 cttcctgcat cacccgttca cttctcatgc acgtagcggc ccggcgcgtc gtcgagcgcg
     2041 ggatagttta cggcaccgat cgccggcggc gccacgcgcg cgccgctgcg cgcggcgagc
     2101 cagtcgctcc aggccggcca ccacgagcct tcctgctcgg gcgtgcgctc gagccagtcg
     2161 tccggcggga cgtagttgcc gcccgccggg cgcgtgcgca ggcggaagct gcgccgcggg
     2221 cggccgggtt cgctgacgat gccggcgttg tggccgccgc tggtgagcac gaagctgatc
     2281 tcggtcggca ccaggtagtg cagcttgtag accgagcgcc agggcgcgac gtggtcggtg
     2341 agggtggcga cgcagaacac cggcagctcg atgtcggaca gcgccaccgg cttgccgccc
     2401 acggggtagc gcccctcgct gaggtcgtcg ttgaggaaga gccggcgcag gtactggctg
     2461 tgcatgcgcg cgggcatgcg ggtggcgtcg gcgttccagg ccatgaggtc gttcatcggc
     2521 gtgcgctcgc ccatgaggta ttcgccgacg atgcgcgacc acagcaggtc gttggagcgc
     2581 aggatctgga aggcgcccgc catctggccg gcggtgagga agccggtctc ctccatctgc
     2641 gcctcgagca ggctgacctc gctctcgtcg atgaagagcg cgagctcgcc cggctcggtg
     2701 aagtcggtct gcgcggtgaa tagcgtcatc gagcccagcc gggtgtcgcc gtcgcggtcc
     2761 atcgccgcgg cggcgatcgc cagcagggtg ccgccgaggc agtagccggt ggcgtgcacc
     2821 ttctgcccgg ggacgatggc attgatggcg tcgagcgcgg cgaagaagcc gagctgcagg
     2881 tagtcgtcca tgtcgagcgt gcgctcgtcc gtccccgggt tcttccacga gatgcagaac
     2941 accgtgtggc cgcgctcgac caggtacctg accagcgagt tgtgcggcga gaggtcgagg
     3001 atgtagtact tcatgatcca ggccggcacg atcagcaccg gctcggcgta aacatcggcg
     3061 gtggcgggcg cgtactggat gagctcgatg aggcggttgc gcagcaccac cttgccgggg
     3121 gtgacggcca cgtcgcggcc gacgacgaaa tcctcggcgc ccgccggcgg ggcgccgccg
     3181 accaggcgct cgaagtcctc gacggcgtgg atggcgccgc gcacgaggtt caagccgccg
     3241 ctctcctgcg tctggcgcag caccacgggg ttggtgggca ggaagttgcc cggcgagaac
     3301 aggtcgagca gctggcgcgc ggcgaaggcg acgacctgct cgtggtggcg cgacacgccg
     3361 gccacgccgt gggtggcggc gtcccaccac tcctggccga gcaggaagga ctggtgcatc
     3421 aggttgaagg gccaggcgtg ccactcgggc gccttgaagc ggcggtcctg cgcgggcggc
     3481 tcgatgcatt cgtgcgcggc gctgcccgcg ggggcgacgg cgagctgctg cgcgtaacgc
     3541 agcaggcggc gcgtctgctc gatgccgagg tcggcgagct ccatgcgctt gcctggcgac
     3601 agtgcgaggt ggccggccca gtccaccgcg gccagcagca gcgcgatcgg cgacaccgag
     3661 gcggtggcgc gcgcgatggc cgcatgcacg cggcgatcga gcgggttgcg cggcggtggc
     3721 ggggcgaagg gtgcggcaaa gctgcgcgcg gggtgagcgg tggggcgggc gagcggtttc
     3781 ggcgtctgcg cgtgcgtcgc ggagggggcg ctcgaggcgg gtgtgcttgc accggacgcg
     3841 ttcgcgcgtg ctccgcgtgc aggtttgccg gccgtgccgg tggccgcttc attcagcggc
     3901 tggcgccgcg tgcgcgccgg cgcggcttgc ctggagggcg gcttgggggc ggatggactc
     3961 atcggcattc tcctttcgcg agggttcaat tctgcatcgt tccgatggtg tgacgcaggc
     4021 ggtggtgcgc caggcccagg aagaccgcgc cgatcgccgc caccatcgcg aaggccggcc
     4081 acaccacgtc caccccggcg ccgcggaaga ggatggcctg cgcgagcgac acgtagtgcg
     4141 tggtcggggc cagcgccatg atggcctgga tggcctcggg catgctctcg cgcggggtca
     4201 cgccgccgga gaggatctgc agcggcagca gcacgaggat ggacatcagc ccgaactgcg
     4261 gcatgctgcg cgcgatcgtg cccatgtaga tgccgatcga ggcggcggcg aagaggtaga
     4321 gcagggtgcc ggcgccgaac agcacggccg agcccgccac cgtgatgccg agcacgccct
     4381 tcaccatcac ctgcagcgag aacgacgagg ccaccagcac caccacgccc atggcccaga
     4441 tcttcgacag catgatctcg agcggggtga ccggcatcac cagcaggtgc tcgatggttc
     4501 cgtgctcgcg ctcgcggatc agcgccgcgc cggtgagcag gatgccgagc atggtgacgt
     4561 tgttgatgat ggcgttgatc gcggcgaacc agctcgcctc gaggttgggg ttgaacatgg
     4621 cgcgcgggac gagctcgacc ggctgcggcg ccggcgcgcg catgcgctgc acgaaggcgc
     4681 gcacctcgtc ggcgatgatg ttctggatgt agccggcgcc ggtctgcgcc tggccctggc
     4741 gggtggcgtc gatgttgagc tgaagcgccg ggctgcggcc ggcgagcacg tcgcgctgga
     4801 agttgggcgg gatgtcgagc acgaaggtgt ggcggccggc gtccagcccg cggtccatgt
     4861 cggcgaggcc gacgtgctcg gggggcagga actgcggcgg ctgcagcgcg gcgacgatgc
     4921 ggccggagag ctgcgagccg tcctcgtcca ccaccgcgat cgatgcgcgc gacaggctct
     4981 cgggcttggc gcgggcgtcg gcgtagatcg acgcgctgaa catgaagacg atcaggaaga
     5041 ccatcgcgaa gtcgcgcgac agactgcgga actccttgag gccgaggttc cagatgttgc
     5101 gcaggtgggt ggcgtggtcc gtgtgcttcg gggggctcgg cgtgggtggc gggcctggcg
     5161 ggttcggggg cgtggggtgg cgggccatgg tggcggcgct cacttggcct gcttcttcag
     5221 cagcagcgcc gacagcaggg tgagcacggg gatcgcgagc gcgagcggca cgaaggaccc
     5281 gacgaggtcg gcgaagccga gcgccttgga gaaggtgccg ctggcgatgg tgaggaagtg
     5341 ggtggtgggg tagatggcgc cgatccagta gccgccgccc tcgagcgcgc tcaccgggtc
     5401 catcagcccg gagaactgga tcgccggcag cagggtgccg atcgaggtgc cggcgagcgc
     5461 ggcgacctgg ctgttggtga gcgtggaggc gagcaggccg aggccggtgg tggcggcgac
     5521 gtagagcagg gcgccggtgg cgagggcgag caggctgccc ttgaagggca cctggaacag
     5581 ggtcactgcg agcacgaaga ggagcgcgaa gttgaacatc gacagcgcga tgtagggcag
     5641 ctgcttgccg agcaggaact cgagcttggt gaccggcgtg gtgtagacgt tgaggatgga
     5701 gccgagctcc ttctcgcgca ccacgccgag cgcggtgagc atggcgggga tgaagaccag
     5761 cagcagcggg atcaccttgg gcaccatcga caccaggctg agcagctcgg ggttgtagcg
     5821 gtagcgcggc tccacggtgg cgagcgcgcg caccgggccg gcgccggatt cggcgatcac
     5881 gtcggcgagc gtctgcgcgt gcacgccgcc gacgtaggcg cgcgcgagct cggcgcgcag
     5941 cggcatcgaa ccgtccagcc acaccgccac ctgcggcgcc ttgccgcgcg cgagctcgcg
     6001 gccgaagccg ggcgggatct cgatcgccat cgccagcctg cccgcacgca tgcgcgcgtc
     6061 gaggtcggcg tggctgtcga gcggcgcctg ctccaggaag tagcgcgagc cggcgatgcg
     6121 cagggtgtag ctctggctgg cgacgctgcg gtcgtggtcg agcaccgcgt agtgcaggtc
     6181 ctcgacgtcc atggtgatgc catagcccat caccagcatc agcaacaggc tgccgagcag
     6241 cgccagcgtc agccgcaccg gatcgcgccg cagctcggtg gcctcgcgcg ccgagaagct
     6301 gagcaggcgg ccgaggctga agcgggcgat gcggtcggcg gctggagtcg gcgtggtcgg
     6361 cgcgtcgccg ccg
//
LOCUS       DAOTIN010000163         6277 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_14741_length_6277_cov_8.611058, whole genome shotgun sequence.
ACCESSION   DAOTIN010000163 DAOTIN010000000
VERSION     DAOTIN010000163.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 6277)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 6277)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6277
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_14741_length_6277_cov_8.611058"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(40..501)
                     /locus_tag="P5537_15635"
                     /pseudo
     CDS             complement(40..501)
                     /locus_tag="P5537_15635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292872.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-phosphate dependent enzyme"
     gene            complement(527..1264)
                     /locus_tag="P5537_15640"
     CDS             complement(527..1264)
                     /locus_tag="P5537_15640"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HRV79520.1"
                     /translation="MILLVDAGNTRVKWRVVSMDSPARALAEGAVGHAEIDMLAAACR
                     AWPGLVRVLGCNVAGTSVAARVAAACAPLRVDWLLPTAACAGVRNLYDNPERLGADRW
                     AALIGARHSHAGACLVVTAGTATTVDLLSAAGDFLGGLILPGVELMQQALARGTAQLP
                     LAEGRFAWQPRRTVDAIRSGCLQAQTGAVERMFRQIAAQPDALCLLGGGAADSFADLL
                     EIPLRRIDNLVLTGLGTVATLPAPPTR"
     gene            complement(1261..2094)
                     /locus_tag="P5537_15645"
     CDS             complement(1261..2094)
                     /locus_tag="P5537_15645"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HRV79521.1"
                     /translation="MSSIPPSTPSTRACATELASLLGARAHDFAIEWVACCDSTNALL
                     VDAPPADDGRVHVLVTDRQTAGRGRRGRQWLSWEGASLTFSLLWRFAPGTPAPAGLSL
                     AAGLALARALEQLGVEGVQLKWPNDVLVHGDKLAGILVELLPMRGRPPAAVIGIGLNL
                     RLPADAVVPDQAGVADLAGALGGEPPSRPALLAAILGEFHRLFETYAAAGFPALRGAW
                     EQRNAFADLPVAVRGESATLYGTCIGVDDDGALLLRGEDAIQRVLAGDVSLRPLMDGP
                     R"
     gene            complement(2182..3606)
                     /gene="ntrC"
                     /locus_tag="P5537_15650"
     CDS             complement(2182..3606)
                     /gene="ntrC"
                     /locus_tag="P5537_15650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulation protein NR(I)"
                     /protein_id="HRV79522.1"
                     /translation="MNTVWIIDDDRSIRWVLEKALGREGIDHASFSSAGDALAELERA
                     PQPPAALLSDIRMPGESGLDLLQKVKERHPQLPVIIMTAYSDLDSAVAAFQGGAFEYL
                     PKPFDVDQAVALVRRALEQTAHQNGASEEATLAPEILGQAPAMQEVFRAIGRLAHSHA
                     TVLINGESGSGKELVARALHRHSPRRDAPFIAINTAAIPRDLLESELFGHERGAFTGA
                     ATQRRGRFEQADGGTLFLDEIGDMPAELQTRLLRVLSDGHFYRVGGQQPIRANVRVIA
                     ATHQDLEERVRQGLFREDLFHRLNVIRLRLPPLRERREDIPLLVRHFLQKSAQELGVE
                     RKRISDATLEYLQAQPFPGNVRQLENLCHWLTVMAPAQVVEVADLPPEMREQPGRESP
                     SNWMEGLGSEADRLIASRPGEVFDRLTREFERTLIRRALAATGGRRIEAAQLLGIGRN
                     TISRKIQELGMDEERTPEAEESGR"
     gene            complement(3672..4748)
                     /gene="glnL"
                     /locus_tag="P5537_15655"
     CDS             complement(3672..4748)
                     /gene="glnL"
                     /locus_tag="P5537_15655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulation protein NR(II)"
                     /protein_id="HRV79523.1"
                     /translation="MPSQPTHATSDPGSPFAGLDLLSSAVVLVDAGLAIRYLNAGAEN
                     LFAISQRKLLGQPLERLLGSPPGLGAALDNALRTNWSYTGQDISVQRGDAEPLRLDCT
                     VTPVDTAGVRLLLEFRPIDAQLRVAREEQLLHQQQANRELIRNLAHEIKNPLGGIRGS
                     AQLLQHELDDPQLREFTDVIIAEADRLQDLMNRLLSSHCMMRPATINLHDVLERVRRL
                     ILAEFPSIRIVPDYDLSLPELTADREQLIQAVLNIVRNAAQALGGRGEILLRTRIARQ
                     VTLAKRRHKLALELQVIDDGPGIPEEIRDRIFYPLVSGREGGSGLGLSLAQSFIEQHQ
                     GMIEVESRPGRTCFTILLPITERN"
     gene            complement(4802..5287)
                     /locus_tag="P5537_15660"
     CDS             complement(4802..5287)
                     /locus_tag="P5537_15660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4124 domain-containing protein"
                     /protein_id="HRV79524.1"
                     /translation="MRTYRILPLLLLAGLASPALAEIYKCTDAAGRVTYTNDRSLARG
                     CVRLQSDQPVSSVPAPVRRPAAPAARDTAQSADFPRVSPNEQRGRDDARRQVLQEELR
                     TEEQKLAEAEKALAEQESIRLGDERNYQKVLDRVQPFKDRVELHKRNVEALRREISGL
                     R"
     gene            complement(5424..>6277)
                     /gene="glnA"
                     /locus_tag="P5537_15665"
     CDS             complement(5424..>6277)
                     /gene="glnA"
                     /locus_tag="P5537_15665"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015434326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HRV79525.1"
                     /translation="IVVDDVRAAMVLALEACGVPVEVHHHEVANAGQCEIGTKFSTLT
                     QRADWTQVLKYIVHNVAHQYGKTATFMPKPIVGDNGSGMHVHQSIWKDGKNLFAGNGY
                     AGLSETALYYIGGIIKHARALNAITNPGTNSYKRLVPHYEAPTKLAYSARNRSASIRI
                     PYTANPKGRRIESRFPDPLANPYMCFAALMMAGLDGIQNKIHPGDPADKNLYDLPPEE
                     DALIPTVCTSLDQALEYLDKDREFLTRGGVFSNDFIDAYIALKMEEVDRMRITTHPVE
                     FDMYYSL"
BASE COUNT          865 a         2030 c         2406 g          976 t
ORIGIN      
        1 ggccttctac aacaagcagg ccggcatcaa gcgcctgacc acctccagcc cgaacatctg
       61 cccggcgaag gcgatcgacg agccccactg tccggcgccg gtctcggtgg tcaggcgctt
      121 gatgccggcc tgcttgttgt agaaggcctg cggcaccgcc gagttgggct tgtgcgagcc
      181 ggcgggcgag acgccctcgt acttgaagaa gatcttcgcc ggggtgccga gcgcctgctc
      241 caagcgcact gcgcgacaca gcgggctggg ccgccacagg cggtagatct cgcgcacctc
      301 ctgcgggatg gcgatccagc gctccgcgct catctcctgc tcgaggatcg caggcgggaa
      361 gatggccccc atctgctcgg gcgtggccgg cttgccgtcg gggccgagcg gcggcgcgag
      421 cggggtcggc aggtcggcgg cgacgttgta ccagtgcgtc gggatgtcgg cggcgtcgag
      481 caggatgcgg gtggcttcca tcgttgtttt ctccctttcg gtattgtcag cgtgtgggcg
      541 gggcgggcag ggtggcgacc gtgcccaggc cggtcagcac cagattgtcg atccgtcgca
      601 gcggaatctc gagcaggtcg gcgaagctgt cggcggcgcc gccgccgagc aggcagagcg
      661 catcgggctg cgccgcgatc tggcggaaca tgcgctcgac cgcgccggtc tgggcctgca
      721 ggcatcccga gcggatcgca tccaccgtgc gccgcggctg ccatgcgaag cggccctcgg
      781 cgagcggcag ctgcgcggtg ccgcgggcga gcgcctgctg catcagctcg accccgggca
      841 ggatcaggcc accgaggaag tcgcccgccg cggacagcag gtccaccgtg gtggcggtgc
      901 ctgcggtgac caccaggcag gcaccggcgt ggctgtggcg ggcgccgatc agcgccgccc
      961 agcgatcggc gccgaggcgc tcggggttgt cgtagaggtt gcgcacgccg gcgcaggccg
     1021 cggtgggcag cagccagtcc acccgcagcg gtgcgcaggc ggcggcgacg cgcgcagcga
     1081 cgctggtgcc ggcgacgttg cagccgagca cgcgcaccag cccgggccag gcgcggcatg
     1141 cggcggcgag catgtcgatc tcggcgtggc ccaccgcgcc ctcggcgagc gcacgggcgg
     1201 gggaatccat ggagaccacg cgccatttca cgcgggtgtt gccggcatcg acgagcagga
     1261 tcatcgcggg ccgtccatca gcgggcgcag cgagacgtcg cccgccagca cgcgctggat
     1321 ggcgtcctct ccgcgcagca gcagggcgcc gtcgtcgtcc actccgatgc aggtgccgta
     1381 cagcgtggcc gactcgccgc ggaccgccac cggcaggtcg gcgaaggcgt tgcgctgctc
     1441 ccaggccccg cgcagggcgg ggaagccggc ggcggcgtag gtctcgaaga ggcggtggaa
     1501 ctcgccgagg atggccgcca gcagcgccgg acgcgagggc ggttcgccgc cgagcgcacc
     1561 ggcgaggtcg gcgacgcccg cctggtcggg gacgacggcg tcggccggca ggcgcaggtt
     1621 caggccgatg ccgatcaccg ccgcgggcgg gcggccgcgc atggggagga gctcgaccag
     1681 gatgccggcg agcttgtcgc catgcaccag cacgtcgttg ggccacttga gctgcacgcc
     1741 ctcgacgccg agctgctcga gcgcgcgcgc gagcgcgagc ccggcagcga gcgagagccc
     1801 agccggggcc ggcgtccccg gggcgaagcg ccacagcagc gagaaggtga ggctggcgcc
     1861 ctcccaggac agccactgcc gcccgcgtcg cccgcgcccg gcggtctggc ggtcggtcac
     1921 gagcacatgc acgcggccgt cgtcggcggg cggggcgtcg accaggaggg cgttggtcga
     1981 gtcgcagcac gccacccatt cgatggcgaa atcgtgcgcg cgtgcgccga ggagggaggc
     2041 cagttcggtc gcgcaggcgc gcgtcgaagg cgtggatgga gggatggagg acaagtgcgg
     2101 gagcggcgga ccgaaaaccg cattatccgc caagaccgcg gcggatgtgc ctcccgcggc
     2161 atggatgcga tcggggaacg ctcagcgccc gctctcctcc gcctccggcg tacgttcctc
     2221 gtccatgccc agctcctgga tcttgcggct gatcgtgttg cggccgatgc cgagcagctg
     2281 cgcggcctcg atgcggcgcc cgccggtggc ggcgagcgcg cggcggatca gggtgcgctc
     2341 gaactcgcgc gtgaggcgat cgaagacctc gcccgggcgc gaggcgatca ggcggtcggc
     2401 ctcgctgccg aggccctcca tccagttcga cggcgactcg cggccaggct gctcgcgcat
     2461 ctcgggcggc aggtcggcca cctccaccac ctgcgccggc gccatcacgg tcagccagtg
     2521 gcacaggttc tcgagctggc gcacgttgcc ggggaagggc tgggcctgca ggtattcgag
     2581 cgtggcgtcc gagatgcgct tgcgctcgac gccgagctcc tgcgcactct tctgcaggaa
     2641 gtggcgcacc agcagcggaa tgtcctcgcg gcgctcgcgc agcggtggca ggcgcaggcg
     2701 gatgacgttg aggcggtgga agaggtcctc gcggaacagg ccctggcgca cgcgctcctc
     2761 caggtcctgg tgggtggcgg cgatcacgcg cacgttggcg cggatcggct gctggccgcc
     2821 gacgcggtag aagtggccgt cggagagcac gcgcagcagc cgggtctgca gctcggccgg
     2881 catgtcgccg atctcgtcga ggaagagcgt gccgccgtcg gcctgctcga agcggccgcg
     2941 gcgctgggtg gcggcgccgg tgaaggcgcc gcgctcgtgg ccgaagagct cggattcgag
     3001 caggtcgcgc gggatggcgg cggtgttgat ggcgatgaac ggcgcgtcgc ggcgcgggct
     3061 gtggcggtgc agcgcgcgcg cgaccagctc cttgccactg cccgactcgc cgttgatcag
     3121 caccgtggcg tgggagtgcg cgagccggcc gatggcgcgg aagacctcct gcatcgccgg
     3181 ggcctggccg agaatctcgg gagcgagggt ggcttcctcg cttgcaccgt tctggtgcgc
     3241 ggtctgctcc aatgcacgcc ggacgagcgc gaccgcctgg tcgacgtcga agggcttggg
     3301 caggtactcg aaggcgccgc cctggaaggc cgccactgcg ctgtcgaggt cggagtaggc
     3361 ggtcatgatg atgaccggca gctgcgggtg gcgctccttg accttctgca gcaggtccag
     3421 ccccgactcg ccgggcatgc ggatgtccga cagcagcgcg gccggcggct gcggcgcgcg
     3481 ctcgagctcg gcgagggcgt cgccggcgga gctgaagctg gcgtggtcga tgccctcgcg
     3541 gccgagcgcc ttttcaagca cccagcggat cgagcggtcg tcgtcgatga tccagacggt
     3601 attcatatcg tatgcactat tctggtgcgc gctgctcgcc cggcgttccg cgggagggac
     3661 gccggatgcg ctcagttgcg ctcggtaatc ggcagcagga tcgtgaagca ggtgcgcccg
     3721 ggacggcttt ccacctcgat catgccctgg tgttgctcga tgaagctctg cgcgagcgac
     3781 aggcccagcc cgctgccgcc ctcgcgtccc gacaccagcg gatagaagat ccggtcgcgg
     3841 atctcctcgg ggatgccggg gccgtcgtcg atcacttgca attcgagtgc cagcttgtgg
     3901 cggcgcttgg cgagcgtcac ctggcgcgcg atgcgggtgc gcagcaggat ttcgccgcgg
     3961 ccgccgagcg cctgcgcggc attgcgcacg atgttgagca ccgcctggat gagctgctcg
     4021 cggtcggcgg tgagctcggg caggctgagg tcgtagtcgg ggacgatccg gatcgacggg
     4081 aactcggcga ggatcaggcg ccgcacgcgc tcgagcacgt cgtggaggtt gatcgtcgcc
     4141 ggtcgcatca tgcagtgcga gctcagcagt cggttcatca gatcctgcag gcggtcggcc
     4201 tcggcgatga tgacgtcggt gaattcgcgt agctgcggat cgtcgagctc gtgctgcagc
     4261 agctgcgccg agccgcggat gccgccgagc gggttcttga tctcgtgcgc gaggttgcgg
     4321 atgagttcgc ggttggcctg ctgctggtgc agcagctgct cctcgcgcgc cacgcgcagt
     4381 tgggcgtcga tcgggcggaa ctcgagcagc aggcgcacgc cggcggtgtc gaccggggtc
     4441 accgtgcagt cgagccgcag cggttcggcg tcgccgcgct gcacgctgat gtcctggccg
     4501 gtgtagctcc agttggtgcg cagcgcgttg tcgagcgccg cgcccaggcc gggagggctg
     4561 ccgagcaggc gctcgagcgg ctggccgagc agcttgcgct ggctgatcgc gaacaggttc
     4621 tccgcgcccg cgttgaggta gcggatcgcc agcccggcgt cgacgagcac gaccgccgag
     4681 gacagcagat cgagcccggc gaaagggctg ccggggtcgc ttgtggcgtg ggtgggttgc
     4741 gatggcatgg gcgcgtcctg ttgtttggcg gaggacatgc aagatgcgcg ccaggtccgg
     4801 gtcatcgcag gccggagatc tcccggcgca gcgcctcgac gttgcgcttg tgcagttcga
     4861 cgcggtcctt gaagggctgc acgcggtcga gcaccttctg gtagttgcgc tcgtcaccga
     4921 ggcggatgga ctcctgctcg gcgagcgcct tctcggcttc ggccagcttc tgctcctcgg
     4981 tgcgcagctc ttcctgcaac acctggcggc gggcgtcgtc gcggccgcgc tgctcgttcg
     5041 ggctcacgcg cgggaagtcg gccgattgcg cagtgtcgcg ggccgccggt gcggcaggac
     5101 ggcgcaccgg tgccggcacc gaggataccg gctggtcgga ttgcaggcgc acgcagccac
     5161 gcgccaggga tcggtcgttg gtataggtca cccgaccggc ggcgtcggtg cacttgtaga
     5221 tttcggcaag ggccggcgag gcaaggccgg cgagcaggag cagcggaagg attcgatacg
     5281 ttcgcatgcg catgtccgga gggtcgcggg gacggcggga gcgggctgca atgccgtcat
     5341 ccttgcgggt caggcccgat tagaccccag aaaaaaggga cgggcaacgc ccgtcccttc
     5401 cgtcctgcgc aggatctccc ggcttacagg ctgtagtaca tgtcgaattc caccgggtgg
     5461 gtggtgatgc gcatgcggtc gacctcttcc atcttcagcg cgatgtaggc gtcgatgaag
     5521 tcgttggaga acacaccgcc acgggtcagg aactcgcgat ccttgtccag gtactccagc
     5581 gcctggtcga ggctggtgca cacggtcggg atcagcgcgt cctcttccgg cggcaggtcg
     5641 tagaggttct tgtcggccgg gtcgcccggg tggatcttgt tctggatgcc gtccaggccc
     5701 gccatcatca gcgcggcgaa gcacatgtac gggttggcca gggggtccgg gaagcgcgac
     5761 tcgatgcgac ggcccttcgg gttggcggtg taggggatgc ggatcgaagc cgagcggttg
     5821 cgtgccgagt aggcaagctt ggtcggggcc tcgtagtgcg gcaccaggcg cttgtacgag
     5881 ttcgtgcccg ggttggtgat ggcgttgagc gcgcgggcgt gcttgatgat gccgccgatg
     5941 tagtacagcg cggtctcgga caggccggcg tagccgttgc ccgcgaacag gttcttgccg
     6001 tccttccaga tcgactggtg cacgtgcatg ccggagccgt tgtcgccgac gatgggcttg
     6061 ggcatgaagg tggcggtctt gccgtactgg tgggcgacgt tatgcacgat gtacttgagc
     6121 acctgggtcc agtcggcgcg ctgggtcagc gtgctgaact tggtgccgat ctcgcactgg
     6181 ccggcgttgg ccacctcgtg gtggtgcacc tcgaccggca cgccgcaggc ctcgagcgcg
     6241 agcaccatgg cggcgcgcac gtcgtcgacg acgatct
//
LOCUS       DAOTIN010000164         6271 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_14762_length_6271_cov_8.898970, whole genome shotgun sequence.
ACCESSION   DAOTIN010000164 DAOTIN010000000
VERSION     DAOTIN010000164.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 6271)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 6271)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6271
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_14762_length_6271_cov_8.898970"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..546
                     /locus_tag="P5537_15670"
     CDS             <1..546
                     /locus_tag="P5537_15670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HRV79526.1"
                     /translation="LFDGVITVDPHLHRISSLAEAIPVPHALALSGAGLLADVAVAQR
                     ERPLLVGPDAESAQWIETAAQRHGLGAVVCTKIRHGDREVDIALPEDARVAGRAVVLL
                     DDVASSGRTLARAAERLLAAGAASVDVAVTHALFAGDALEVIRAAGVGEVWSTDCIAH
                     PSNAVQIAPMLAEALREVLAD"
     gene            740..1633
                     /locus_tag="P5537_15675"
     CDS             740..1633
                     /locus_tag="P5537_15675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004336646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate/guanylate cyclase domain-containing
                     protein"
                     /protein_id="HRV79527.1"
                     /translation="MIFADLTGSTGLFESAGNVAATQIVTRCTHALGRHLACAGGRIV
                     KYLGDGVLVLFDDPVAAVQAASRLQDVLEELASAELRRAPIGVKTGVALGPIVEHDGD
                     CYGDPVNVAARLSDRAQTGETLIGEAVFTELPDGLRLACHSLDRITIKGKAEPMRVWR
                     VDFARTAETTLTTLLGFDDLVAGARPVRRVDLERLDQRIGLHADDPPLILGRGDGAGF
                     PVEDARVSRRHARLEWTAGQCVLTDFSSNGSWVRFRGISAPVVLRRDSCTLYGEGEIG
                     LGAAPDDFTAPTLTFRVIDEG"
     gene            1706..2701
                     /locus_tag="P5537_15680"
     CDS             1706..2701
                     /locus_tag="P5537_15680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HRV79528.1"
                     /translation="MRIPSLLLFLLPFCATAQDWSARTLGEIAVYPEYRAPARVVAGE
                     EARIAAEVGARIVAMPARTGAEVVRGTELVRLDDAAFRIELERARAQVALIDSRIGLA
                     RVQLDQAHTLAGRGFISADGLRIRETELGVLQRERDAARAAQAAAELALARTVIRAPF
                     AGVVRERLAAVGDLAAPGTPLLGLAASADAEVHARVPAAQVDGLLAAAPPTLVAGGAE
                     HALRIVRVSPVLDAAGQARDVILAAASALPPGLAGELRWRSRVPHLPPGYVQQREGRL
                     GAWLVRDAEPRFVVLPEAQAGRPAAVDWPADLQVVDEGRFAIGLQAPAAAAGGTH"
     gene            2698..5772
                     /locus_tag="P5537_15685"
     CDS             2698..5772
                     /locus_tag="P5537_15685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HRV79529.1"
                     /translation="MSGFYRRLIDNHPLANIAFLMVLLGGLFSYLSMPRAQDPEINFN
                     WVSIVTALPGASAEDVERDLTGPLEDAIKQVKDIRFSSSSSREGVSSILVRFEELPER
                     VFDKRVNDLRREIQNKASAELPPDATDPVVIEFTSSNGFPTAILVLHGAGGETLRRAG
                     FVMKKDLEGLDGVDQVIAAGLEDPQLHVDFDPARVAAAGLSPVQVADGVAAWFRNTLA
                     GRVRVQDREWLVRMEGKTPDPEALAQAAVVTPAGRVALDEFASVARGQERPGQLVSYN
                     GAPALMLSITKDADANTLELVERLQAFTAQRNPLLAGQGVQLRLIDDQTHATRHAIGV
                     MESNAVFGLFAVLAMCWIFLGSRLALLVGLGVPFALAGTFIAVDLIDSTLNLTVLLGV
                     VIALGMLVDDAVVIVEAIYYRLQRGDPPHEAVVGGVEEVGLPVLSSVLTTIAAFLPLM
                     LLPGILGKFMFVVPFVVTVGLLVSLVEAYWILPTHILALRPQPSQRRTRAQELRERFT
                     LRIRIAYARALVAVMRRRRLATAVLLLLMAGAGAAVATGLVRVQFFAFDSMRLFYVNV
                     DMPAGVVPERTLAEAERAVKVLGETIGADELRSVAVYAGLKFTETEPVYGDQYAQVLV
                     SLLPRAADGRDAAEVIAAVRPGIEALAGEAKFSFMEMKGGPPTAKPISVKMKSDDYPQ
                     LRAAADALLVEVAKLPGVRDLTDDDVPGRGEMRLALDREKLARAGVQPAEVARLLRLY
                     GEGEIVATTRDGGEKLEVVVRARQESLDDVTGLLQRPVPLADGRSVQLGELVSHQLLL
                     SKGYIRHYQLTRAITVEAELDRERLDTVEANDRLKAAWAQLQPRFPGVELDFSGELED
                     IQESLDAMGKLFALGVGLIYLILATQFRSYWQPLIILLTVPLAFTGVVLGLLVSGNPL
                     SLYTLYGVIALTGIAVNSAIVLIDAANERRAAGMSVQHAAIYAARRRVVPILITTTTT
                     IGGLLSLAIGLGGKSLMWGPVAASIVWGLGFSTVLTLFAVPLVYRMAMQRSR"
     gene            complement(5812..>6271)
                     /locus_tag="P5537_15690"
     CDS             complement(5812..>6271)
                     /locus_tag="P5537_15690"
                     /inference="COORDINATES: protein motif:HMM:NF019843.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79530.1"
                     /translation="GGGRSEHTRVLLDDVIALSPLRLDDDDCALIAEADAGSVEAQCD
                     LGLLLLTQNHPSEAVAWLTRAANQTYPEAMHQLGRCYIAGRGLEASEVFGVEWISRAA
                     ALGHRTARPMARYLMDPGRPRLDAAALEARLDAIEREQVMAVLRETADGN"
BASE COUNT          781 a         2232 c         2281 g          977 t
ORIGIN      
        1 ctgttcgacg gcgtgatcac cgtcgacccc cacctgcacc gcatctccag cctcgccgag
       61 gcgattccgg tgccgcatgc gctcgcgctc tcgggtgccg gcctgctcgc cgacgtggcg
      121 gtcgcgcagc gcgagcgccc gctgctggtg gggccggatg ccgagtcggc gcagtggatc
      181 gagaccgccg cgcagcgcca tgggctgggc gccgtcgtgt gcaccaagat tcgccatggt
      241 gatcgcgagg tcgacatcgc cctgcccgag gacgcgcggg tcgcgggacg tgcggtggtg
      301 ctgctcgacg acgtcgccag ctcgggccgc acgctcgcgc gtgccgccga gcgcctgctc
      361 gcggcgggtg cggcctcggt cgatgtcgcc gtcacccacg cgctcttcgc tggcgacgcg
      421 ctcgaggtga tccgtgccgc cggcgtgggc gaagtctgga gcaccgactg catcgcccac
      481 cccagcaatg cggtgcagat cgcgccgatg ctggccgagg cgctgcggga agtcctcgcc
      541 gactagcgct gccctgcgcg ccctccgccc cgcgcgcgcg ttgccgtggg cgtattgcca
      601 tgtgcgcggc gatgacgatt accgtcctta atgctaggat tcttgcttgc gcactgcagc
      661 gagccccggt tttcggggtc gcgggcggtg cccgcacatc cctcggggca ggaattcagt
      721 ggagcaagcg gtcaggaccg tgatcttcgc cgatctgaca ggcagtacag gcctgttcga
      781 gtcggcaggc aacgtggcgg cgacgcagat cgtcacgcgg tgcacgcacg ccctcggccg
      841 ccacctcgcc tgtgccggcg ggcgcatcgt caagtatctc ggcgatggcg tgctggtgct
      901 gttcgacgat ccggtcgccg cggtgcaggc ggcctcccgc cttcaggacg tgctcgagga
      961 actggccagc gccgagctgc ggagggcgcc gatcggggtc aagaccggcg tcgcgctcgg
     1021 gccgatcgtc gagcacgacg gcgactgcta cggtgacccg gtcaacgttg ccgcgcgcct
     1081 cagcgatcgc gcccagaccg gtgagacgct catcggcgag gcggtgttca ccgagctccc
     1141 cgacgggttg cgcctggcgt gtcacagcct cgatcgcatc accatcaagg gcaaggccga
     1201 gccgatgcgg gtgtggcggg tcgatttcgc ccgcaccgcg gagaccacgc tcaccacgct
     1261 gctcggcttc gacgacctgg tcgcgggggc gcgcccggtg cgccgggtcg atctcgagcg
     1321 cctcgaccag cgcatcgggc tgcacgccga cgatccaccg ctgatcctcg gtcgcggcga
     1381 tggcgccggc ttcccggtcg aggacgcgcg cgtgtcgcgt cgtcatgcgc gcctcgaatg
     1441 gacggcgggc cagtgcgtgc tcaccgattt cagcagcaac ggcagctggg tgcgcttccg
     1501 cggcatctcc gcgccggtgg tgctgcgccg cgacagctgc acgctctacg gcgagggcga
     1561 gatcggcctc ggcgccgccc ccgacgactt caccgcgccc acgctcacct tccgcgtcat
     1621 cgacgagggc tgagggccca tgtgccacgg ggctgcggat gcgtccgccc gctgcggtct
     1681 tgcccatgcc ctgcttcgtg ttgcgatgcg aatcccgagt cttctcctgt tcctgcttcc
     1741 gttctgcgca accgcgcagg actggagcgc acgcacgctc ggcgagatcg cggtgtaccc
     1801 cgagtaccgc gccccggcgc gcgtggtcgc tggcgaagag gcgcgcatcg ccgccgaggt
     1861 cggcgcgcgc atcgtcgcga tgccggcgcg taccggggcc gaggtggtgc gcggcaccga
     1921 gctggtgcgc ctggacgacg ccgccttccg catcgagctc gagcgcgcgc gtgcccaggt
     1981 ggcgctgatc gacagccgca tcgggctggc gcgcgtccag ctcgaccagg cgcacacgct
     2041 cgccgggcgc ggtttcatca gcgccgacgg cctgcgcatc cgcgagaccg agctcggcgt
     2101 gctgcagcgc gagcgcgacg cggcacgtgc cgcccaggcc gcggccgagc tcgcgctcgc
     2161 gcgtaccgtg atccgcgcgc ccttcgccgg cgtggtgcgc gaacgcctcg ccgcggtggg
     2221 cgacctcgcc gcgcccggca cgccgctgct gggcctcgcg gcgagcgccg acgccgaggt
     2281 gcacgcgcgc gtgcccgccg cccaggtcga cgggctgctc gccgccgcgc cgccgacgct
     2341 ggtcgcgggc ggcgcggagc acgcgctgcg tatcgtgcgc gtgtcgccgg tgctcgacgc
     2401 cgccggccag gcgcgcgacg tgatcctcgc cgccgcgtcg gcgctgccgc cggggctggc
     2461 gggcgagctg cgctggcgca gccgggtgcc gcacctgccg ccgggctatg tgcagcagcg
     2521 cgagggccgc ctcggcgcct ggctggtgcg cgacgccgag ccccggttcg tggtgctgcc
     2581 cgaggcccag gccggccgcc ccgccgcggt cgactggccg gccgacctgc aggtggtgga
     2641 cgaggggcgc ttcgcgatcg gcctgcaggc gccggccgcc gcggccgggg ggacgcattg
     2701 agcggcttct accggcggct gatcgacaat catccgctcg ccaacatcgc cttcctgatg
     2761 gtgctgctgg gcgggctgtt cagctacctc tccatgccgc gggcgcagga cccggagatc
     2821 aacttcaact gggtcagcat cgtcaccgcg ctgcccggcg cctcggcgga ggacgtcgag
     2881 cgcgacctca ccgggccgct cgaggacgcg atcaagcagg tcaaggacat ccgcttcagc
     2941 tcctcgtcca gccgcgaggg cgtgtcctcc atcctggtgc gcttcgagga gctgcccgag
     3001 cgggtcttcg acaagcgcgt gaatgacctg cgccgcgaga tccagaacaa ggcctccgcc
     3061 gagctgccgc cggacgcgac cgatcccgtg gtgatcgaat tcaccagctc gaacggcttc
     3121 ccgaccgcga tcctggtgct gcatggcgcc ggcggcgaga cgctgcggcg tgccggcttc
     3181 gtgatgaaga aggatctcga gggcctggac ggcgtggacc aggtgatcgc cgccggcctg
     3241 gaggatcctc agctgcacgt cgatttcgac cccgcccggg tggcggccgc cgggctgtcg
     3301 ccagtgcagg tcgccgacgg ggtggcggcc tggttccgca acaccctcgc cggccgcgtg
     3361 cgggtgcagg accgcgagtg gctggtgcgc atggagggca agacgcccga ccccgaggcg
     3421 ctcgcgcagg ccgcggtggt gacgccggcg ggccgggtgg cgctcgatga gttcgccagc
     3481 gtggcgcgcg gccaggagcg cccgggccag ctcgtgagct acaacggcgc gccggcgctg
     3541 atgctgtcga tcaccaagga tgccgacgcc aacacgctcg agctggtcga gcgcctgcag
     3601 gccttcactg cgcagcgcaa cccgctgctc gccggccagg gcgtgcagct gcgcctgatc
     3661 gacgaccaga cccatgccac ccgccacgcc atcggggtga tggagtcgaa cgcggtgttc
     3721 ggcttgttcg cggtgctggc gatgtgctgg atcttcctcg gctcgcgcct ggcgctgctg
     3781 gtcgggctcg gggtgccgtt cgcgcttgcc ggtaccttca tcgcggtcga cctgatcgac
     3841 tccacgctca acctcaccgt gctgctcggc gtggtgatcg cgctcggcat gctggtcgac
     3901 gacgcggtgg tgatcgtcga ggcgatctac taccgcctgc agcgcggcga tccgccgcac
     3961 gaggcggtgg tgggcggggt ggaggaggtc ggcctgccgg tgctgtcctc ggtgctgacc
     4021 acgatcgcgg ccttcctgcc gctcatgctg ctgcccggta tcctcggcaa gttcatgttc
     4081 gtggtgccct tcgtggtcac cgtcggcctg ctcgtgagcc tggtcgaggc ctactggatc
     4141 ctgcccacgc acatcctcgc gctgcgcccg cagccctcgc agcggcgcac gcgcgcgcag
     4201 gaactgcgcg agcgcttcac cttgcgcatc cgcatcgcct atgcgcgcgc cctggtggcg
     4261 gtgatgcgcc gccgccgcct cgccaccgcg gtcctgctgc tgctgatggc gggtgcgggc
     4321 gcggcggtgg cgaccgggct ggtgcgcgtg cagttcttcg ccttcgactc gatgcggctc
     4381 ttctatgtga acgtcgacat gcccgcgggc gtggtgccgg agcgcacgct ggccgaggcc
     4441 gagcgcgcgg tgaaggtgct gggcgagacg atcggcgccg acgagctgcg ctcggtcgcg
     4501 gtgtatgcgg ggctgaagtt caccgagacg gagccggtgt acggggacca gtacgcccag
     4561 gtgctggtct cgctgctgcc gcgcgcggcc gacgggcgcg acgccgccga ggtcatcgcc
     4621 gcggtgcgtc cgggcatcga ggcgctcgcc ggcgaggcga agttctcctt catggagatg
     4681 aagggcggac cgccgaccgc gaagccgatc tcggtgaaga tgaagtccga cgactacccg
     4741 caattgcgcg ccgccgccga cgcgctgctc gtcgaggtgg cgaagctgcc cggggtgcgc
     4801 gacctcaccg atgacgacgt gccggggcgc ggcgagatgc gcctcgcgct cgatcgcgag
     4861 aagctcgcgc gcgccggggt gcagccggcg gaggtggcgc gcctgctgcg cctctacggc
     4921 gagggcgaga tcgtcgccac cacgcgcgat ggcggcgaga agctggaggt ggtggtgcgt
     4981 gcccgccagg agagcctgga tgacgtgacc ggcctgctgc agcgtccggt gccgctcgcc
     5041 gacgggcgca gcgtgcagct cggcgagctg gtgagccacc agctgctgct gtccaagggc
     5101 tatatccgcc actaccagct cacgcgcgcg atcaccgtcg aggcggagct cgaccgcgag
     5161 cgcctcgaca cggtcgaggc caacgatcgc ctcaaggcgg cgtgggcgca gctgcagccg
     5221 cgcttcccgg gcgtggagct ggatttctcc ggcgagctgg aggacatcca ggagagtctg
     5281 gacgcgatgg gcaagctgtt cgcgctcggc gtcgggctga tctacctgat ccttgccacg
     5341 cagttccgca gctactggca gccgctgatc atcctgctca ccgtgccgct cgccttcacc
     5401 ggggtggtgc tcggcctgct ggtgtcgggc aatccgctgt cgctgtacac gctgtacggc
     5461 gtgatcgcgc tcaccggcat cgcggtcaat tccgcgatcg tgctgatcga cgccgccaac
     5521 gagcgccgcg ccgccggcat gagcgtgcag cacgccgcga tctacgccgc gcgccggcgc
     5581 gtggtgccga tcctgatcac caccaccacc accatcggcg ggctgctctc gctcgccatc
     5641 ggcctgggcg gcaagtcgct gatgtggggg ccggtggcgg cgagcatcgt gtgggggctg
     5701 ggcttctcca ccgtgctgac cctgtttgcg gtgccgctgg tgtatcggat ggcgatgcag
     5761 cgcagtcgat agacaacgag ttcgggcttg ccccctgtgc caagcggtcg ctcagttgcc
     5821 gtccgcggtc tcgcgcagca ccgccatcac ctgttcgcgc tcgatggcat ccagccgggc
     5881 ttccagggca gccgcgtcta gtcgcggtcg gcccgggtcc atcagatagc gcgccatcgg
     5941 tcgtgcggtg cggtggccca gagcggctgc gcgcgaaatc cactcgacgc cgaagacttc
     6001 actcgcttcc agaccgcggc ccgcgatgta gcagcgcccg agctggtgca tggcctcggg
     6061 gtaggtctgg ttggccgccc gggtgagcca ggccaccgct tcgctcgggt ggttctgcgt
     6121 gagcagtagc aagcccaggt cgcactgcgc ctcgacgctg ccggcgtcgg cctctgcgat
     6181 cagcgcgcaa tcgtcgtcgt ccagccgcag cggcgacagg gcaatgacgt catcgagcag
     6241 cacgcgcgtg tgctcactcc tccccccccc c
//
LOCUS       DAOTIN010000165         6121 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_15242_length_6121_cov_9.925321, whole genome shotgun sequence.
ACCESSION   DAOTIN010000165 DAOTIN010000000
VERSION     DAOTIN010000165.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 6121)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 6121)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6121
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_15242_length_6121_cov_9.925321"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1635
                     /gene="ureC"
                     /locus_tag="P5537_15695"
     CDS             <1..1635
                     /gene="ureC"
                     /locus_tag="P5537_15695"
                     /EC_number="3.5.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015438158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009039 - urease activity [Evidence IEA];
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA];
                     GO_process: GO:0019627 - urea metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="urease subunit alpha"
                     /protein_id="HRV79531.1"
                     /translation="GEEVKFGGGKVIRDGMGQGQGVAADVADTIVTNALIIDAVAGIV
                     KADVGLKDGRIWKIGKGGNPDIQPGVTIPIGAGTEVIAGEGMILTAGGIDSHIHWICP
                     QQIEEALSSGVTTMLGGGTGPATGTFATTCTPGPWHIHRMLEAAEAFPMNLGFFGKGN
                     ASLPAPLKEQVQAGVIGLKLHEDWGTTPAAIDNCLTVAEQMDIQVAIHTDTLNESGFV
                     ETTLAAFKDRTIHTFHTEGAGGGHAPDIIRAISRPNVLPSSTNPTRPYTVNTIDEHLD
                     MLMVCHHLDPSIAEDVAFAESRIRRETIAAEDILHDTGAFSMMSSDSQAMGRVGEVVI
                     RTWQTAHKMKLQRGWLAPRRSAAAAVADAVAVVEDSTANDNFRVKRYIAKYTINPAIT
                     HGIAHEVGSIEPGKLADLVLWRPAFFGVKPSLVIKGGMIAAAAMGDPNASIPTPQPVH
                     WRPMFGSFGRALKCAVTFVSQAALHNAAVAALGLQKPLVAVKGCRRVTKADMVLNDAT
                     PEIEVDPETYIVRADGEHLSCEPATTLPLAQRYFLF"
     gene            1693..2241
                     /gene="ureE"
                     /locus_tag="P5537_15700"
     CDS             1693..2241
                     /gene="ureE"
                     /locus_tag="P5537_15700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA];
                     GO_process: GO:0019627 - urea metabolic process [Evidence
                     IEA];
                     GO_process: GO:0065003 - protein-containing complex
                     assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="urease accessory protein UreE"
                     /protein_id="HRV79532.1"
                     /translation="MPMTKDILADFVMQTPAPAVLLIESLYDGDLPASEVLELDFNAR
                     TKSRLRTRLASGTEVGLFLPRGTILRGGHRLRARDGRIVAVRAATEDLLEARCASAAE
                     LARAAFHLGNRHVAVEVGHDVAGDWLRIQADHVLEGMLAGLGAQVSALRAPFEPEAGA
                     YAPGHQHPGDGSGARIHLMAGR"
     gene            2238..2951
                     /locus_tag="P5537_15705"
     CDS             2238..2951
                     /locus_tag="P5537_15705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA];
                     GO_process: GO:0006807 - nitrogen compound metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="urease accessory UreF family protein"
                     /protein_id="HRV79533.1"
                     /translation="MSAATSPPGPGLLPLLRLLQLASPALPVGAYTYSQGLEWAVESR
                     LVRTEAEAAAWIGELLEWSLARFEAPLLARQLVAWSQGDDAEVARLNDDFLASRETAE
                     LRAETVQMGWSLVRLLAELDAFAALPGWRGRLLAIEAPCFPTVWSAAAAAWQVPPDQA
                     LAAYLWAWAENQVMAAVKAVPLGQSAGQRLLATLGERIPALAQGALALPEAAWSDYTP
                     GLAIASCRHETQYTRLFRS"
     gene            2948..3649
                     /gene="ureG"
                     /locus_tag="P5537_15710"
     CDS             2948..3649
                     /gene="ureG"
                     /locus_tag="P5537_15710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004377748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016530 - metallochaperone activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0019627 - urea metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="urease accessory protein UreG"
                     /protein_id="HRV79534.1"
                     /translation="MTPSSAHPGTHSTSIASPHAATHSGPPCSPQRGPLRVGIGGPVG
                     SGKTALTLALCLALRDRYDIAVVTNDIYTAEDAQFLVRNEALAPERILGVETGGCPHT
                     AIREDASINLEAVDRLNARFPGLDIVFVESGGDNLAATFSPELSDLTIYVIDVSAGDK
                     IPRKGGPGITRSDLLVINKIDLAPLVGASLEVMDRDARKMRGDRPFLFSNQKTGQGLR
                     EIIDFIERQGMLAAA"
     gene            3688..4269
                     /locus_tag="P5537_15715"
     CDS             3688..4269
                     /locus_tag="P5537_15715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004377746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HupE/UreJ family protein"
                     /protein_id="HRV79535.1"
                     /translation="MTTRFRSMLAAAALASLSGAALAHPGHAPASFATGFAHPLGGLD
                     HLLAMLAVGLYAARQAGAARLLLPASFVLAMLAGAGLGALGLGLPAVEAGIAASVLVL
                     GLLVALAARLPLTASLALVAAFALFHGHAHHAEMGDATLLGYSLGFALASAALHAAGL
                     ALARAFPDSRGGRLALRLGGGGIAGVGVALLGG"
     gene            complement(4402..5292)
                     /locus_tag="P5537_15720"
     CDS             complement(4402..5292)
                     /locus_tag="P5537_15720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004324684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HRV79536.1"
                     /translation="MNWDDLRFLVTLGREGTLAAAARRLAVDQTTVARRLRALEEGLG
                     TALFERDEGLWRPTAVGARVLERAARIEEDVAGITRLAEAGAGAVGGVVRITAVSALI
                     GEWLVPRLPGLYVRHPELRVDLVATNDNLNVARREADIAIRLARPASGDFLIRKLAEV
                     GFALYGAARGELAVSAGDWVAYNEDLDHTPEMRRLHAMLGDGRIRLRSNSLRGLVRAV
                     AGGIGHGLLPCFVADADPGLIRLSGAEPILHRELWMLIHPDARPLARVAATADWLVER
                     FDAEAASFAGRTPSPRAAPP"
     gene            5408..6010
                     /locus_tag="P5537_15725"
     CDS             5408..6010
                     /locus_tag="P5537_15725"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HRV79537.1"
                     /translation="MSTASIPLRQLSGLPAAPARLSESALVIVDAQNAYRSGVMQLEG
                     VEPALDECARLLARARALKIPVVHIQHDAGPGSPYDPSAECGAIADKVAPVAGEVVVV
                     KHYPNSFVGTELDERLKAAGVKNLVVVGFMTHMCINSTARGAFNLGYAVTVPAAATAT
                     RALPAPDGSVVEAAALQVAALTALADLFAVVVADGAAIPD"
BASE COUNT          872 a         2360 c         2098 g          791 t
ORIGIN      
        1 ggcgaggagg tgaagttcgg cggcggcaag gtgatccgcg acggcatggg ccagggccag
       61 ggcgtcgcgg ccgacgtggc cgacaccatc gtcaccaacg cgctgatcat cgacgcggtg
      121 gccggcatcg tgaaggcgga cgtgggcctc aaggacggcc gcatctggaa gatcggcaag
      181 ggcggcaacc cggacatcca gcccggagtg acgatcccga tcggcgccgg caccgaggtg
      241 atcgccggcg agggcatgat cctcaccgca ggcggcatcg acagccacat ccactggatc
      301 tgcccgcagc agatcgagga ggcgctgagc tcgggcgtca ccaccatgct cggcggcggc
      361 accgggccgg cgaccggcac cttcgccacc acctgcacgc caggaccgtg gcacatccac
      421 cgcatgctgg aggcggccga ggccttcccg atgaacctcg gcttcttcgg caagggcaac
      481 gccagcctgc ccgcgccgct gaaggagcag gtgcaggccg gcgtgatcgg cctcaagctg
      541 cacgaggact ggggcacgac gccggcggcg atcgacaact gcctgacggt ggccgagcag
      601 atggacatcc aggtcgccat ccacaccgac acgctcaacg agtcgggctt cgtcgagacc
      661 acgctggcgg cgttcaagga tcgcaccatc cacaccttcc acaccgaggg cgcgggcggc
      721 ggccatgcgc cggacatcat ccgcgccatc agccggccca acgtgctgcc gtcctcgacc
      781 aacccgacgc ggccgtacac ggtcaacacc atcgacgagc acctcgacat gctcatggtg
      841 tgccaccacc tcgacccctc gatcgccgag gacgtggcct tcgccgagtc gcgcatccgc
      901 cgcgagacca tcgccgccga agacatcctg cacgacaccg gcgcgttctc gatgatgtcg
      961 tccgactcgc aagccatggg ccgggtcggc gaggtggtga tccgcacctg gcagaccgcg
     1021 cacaagatga agctgcagcg cggctggctg gcgccccggc gcagcgccgc ggcggcggtg
     1081 gcggacgccg tcgcggtggt cgaggacagc accgccaacg acaacttccg cgtcaagcgc
     1141 tacatcgcca agtacaccat caacccggcg atcacccacg gcatcgcgca cgaggtgggc
     1201 tcgatcgagc cgggcaagct cgccgacctg gtgctgtggc ggccggcctt cttcggcgtc
     1261 aagccgagcc tggtgatcaa gggcggcatg atcgcggcgg cggcgatggg cgaccccaac
     1321 gcctccatcc cgacgccgca gccggtgcat tggcggccga tgttcggcag cttcgggcgc
     1381 gcgctcaaat gcgcggtgac cttcgtgtcg caggccgcgc tgcacaacgc cgcggtcgcc
     1441 gcgctcgggc tgcagaagcc gctggtcgcg gtgaagggct gccgcagggt gaccaaggcc
     1501 gacatggtgt tgaacgacgc cacgcccgag atcgaggtcg accccgagac ctacatcgtg
     1561 cgcgccgacg gcgagcacct gagctgcgag cccgccacca cgctgccgct ggcgcagcgc
     1621 tatttcctgt tctagggcgc agccgccgct cgcgtgcgac gccctttgcc caagccctgg
     1681 agggctccga ccatgccgat gaccaaggac attctcgccg acttcgtgat gcagacgccc
     1741 gcgcccgcgg tgctgctgat cgagtccctg tacgacggcg acctgccggc gagcgaggtg
     1801 ctcgagctcg acttcaacgc ccgcaccaag agccgcctgc gcacgcggct tgcctccggc
     1861 accgaggtcg gcctgttcct gccgcgcggc accatcctgc gcggcgggca caggctgcgc
     1921 gcgcgcgacg gccgcatcgt cgcggtgcgc gccgcgaccg aggacctgct cgaggcgcgc
     1981 tgcgcctcag cggcggagct ggcgcgcgcc gccttccacc tcggcaaccg ccacgtcgcg
     2041 gtcgaggtcg ggcacgacgt ggccggcgac tggctgcgca tccaggccga tcacgtgctc
     2101 gaaggcatgc tggcggggct gggcgcgcag gtgagcgcgc tgcgtgcccc cttcgagccc
     2161 gaggccggcg cctacgcgcc cggccaccag cacccgggcg acggcagcgg cgcgcgcatc
     2221 cacctgatgg cggggcgatg agcgccgcca cctccccccc ggggcccggc ctcctgccgc
     2281 tgctgcgcct gctgcagctg gccagcccgg ccttgccggt cggcgcctac acctactcgc
     2341 agggcctgga gtgggcggtg gagagcaggc tcgtgcgcac cgaggcggag gccgcggcct
     2401 ggatcggcga actgctggaa tggagcctgg cgcgcttcga ggcgccgctg ctggcccgcc
     2461 agctggtggc gtggtcgcag ggcgacgacg ccgaggtggc gcggctcaat gacgacttcc
     2521 tcgccagccg cgagaccgcc gagctgcgcg ccgagacggt gcagatgggc tggtcgctgg
     2581 tgaggctgct ggccgagctc gacgccttcg ctgccttgcc gggctggcgc ggccgcctgc
     2641 tcgcgatcga ggccccatgc ttccccaccg tctggtccgc ggccgcggcg gcgtggcagg
     2701 tgccgcccga ccaggcgctc gccgcctacc tgtgggcctg ggccgagaac caggtgatgg
     2761 cggcggtgaa ggccgttccg ctcggccaga gcgccggcca gcgcctgctc gccaccctgg
     2821 gcgagcgcat cccggcactg gcccagggcg cgctcgccct ccccgaggcg gcctggagcg
     2881 actacacccc cggcctggcc atcgccagct gccgccacga aacccaatac acgaggctgt
     2941 tccgatcatg actccgtcct ccgcccaccc cggcacgcac tctacctcga tcgccagtcc
     3001 gcacgccgca acgcattccg gtcctccgtg cagcccccag cgcggccccc tgcgcgtcgg
     3061 catcggcggc ccggtcggct ccggcaagac cgcgctcacc ctggcgctgt gcctggcgct
     3121 gcgcgaccgc tacgacatcg ccgtggtcac caacgacatc tacaccgccg aggacgccca
     3181 gttcctcgtg cgcaacgagg cgctcgcacc cgagcgcatc ctcggcgtgg agaccggcgg
     3241 ctgcccgcac accgcgatcc gcgaggacgc ctcgatcaac ctggaggcgg tcgaccgcct
     3301 caacgcgcgc ttccccggac tcgacatcgt cttcgtcgag tcgggtggcg acaacctcgc
     3361 cgccaccttc tcgcccgagc tctcggacct gacgatctac gtgatcgacg tctccgccgg
     3421 cgacaagatc ccgcgcaagg gcgggccggg catcacccgc agcgacctgc tggtgatcaa
     3481 caagatcgac ctcgcgccgc tggtcggcgc ctcgctcgag gtcatggacc gcgacgcgcg
     3541 caagatgcgg ggcgatcgcc ccttcctgtt ctcgaaccag aagaccggac agggcctgcg
     3601 tgagatcatc gacttcatcg agcgccaggg catgctggcc gccgcctgaa caccgcaaga
     3661 ccttcccgca ctccaggaga atccaccatg acgacccgct tccgctccat gctcgccgcc
     3721 gccgcgctcg ccagcctctc gggcgcagcg ctcgcccacc ccgggcatgc gccggccagc
     3781 ttcgccaccg gcttcgccca tccgctgggc gggctcgacc acctgctggc catgctcgcg
     3841 gtcggcctct acgccgcgcg ccaggccggc gctgcccgcc tgctgctgcc cgccagcttc
     3901 gtgctggcga tgctcgccgg cgccggcctg ggcgcgctcg gcctcggcct gccggcggtc
     3961 gaggccggca tcgccgcctc ggtgctggtg ctgggcctgc tggtcgcgct cgccgcgcgc
     4021 ctgccgctga cggccagcct ggcgctggtc gccgccttcg cgctcttcca cggccacgcc
     4081 caccacgccg agatgggcga cgccacgctg ctcggctaca gcctcggctt cgcgctcgcc
     4141 agcgcggccc tgcatgcggc cggcctggcg ctcgcgcgcg ccttccccga cagccgcggc
     4201 ggacgcctgg cgttgcgcct cggcggcggc gggatcgccg gcgtgggcgt cgccctgctc
     4261 ggcggctgaa gcccccgtcg gcaagaggcc acgccagggc cacggccgct tcgaggctac
     4321 ggtggcgccg ggactacggc ggtgccgggg cctaaggcgg cgctacggcc gctccggggc
     4381 caaagcggcg ctaaggcggc gttacggcgg cgcggcccgg ggcgacggcg tcctgcccgc
     4441 gaagctcgcc gcctccgcgt cgaagcgctc caccagccag tccgcggtcg cggcgacgcg
     4501 cgcgagcggg cgcgcgtcgg ggtggatcag catccacagc tcgcggtgca ggatcggttc
     4561 cgcgccggac aggcggatca ggccggggtc ggcatcggcc acgaagcagg gcagcagccc
     4621 gtgcccgatg ccgccggcca ccgcgcgcac gaggccgcgc aggctgttcg agcgcaggcg
     4681 gatgcgaccg tcgcccagca tcgcgtgcag gcggcgcatc tccggcgtgt ggtcgaggtc
     4741 ctcgttgtag gccacccagt cgccggcgct caccgccagc tcgccgcgcg ccgcaccgta
     4801 gagcgcgaag ccgacctcgg cgagcttgcg gatgaggaag tcgccgctcg cggggcgcgc
     4861 caggcggatg gcgatgtcgg cctcgcggcg ggcgacgttg aggttgtcat tggtggcgac
     4921 gaggtcgaca cgcagttccg gatggcggac gtacaggcca ggcaggcgcg gcaccagcca
     4981 ctcgccgatc agggcgctca ccgcggtgat ccgcaccacg ccaccgaccg cgccggcgcc
     5041 ggcctcggcc agacgggtga tgccggccac gtcctcctcg atgcgcgcgg cgcgctccag
     5101 cacgcgggcg cccaccgcgg tcggccgcca caaaccctcg tcgcgctcga acagcgccgt
     5161 gcccaggccc tcctccagcg cgcgcaggcg gcgcgcgacc gtggtctggt ccaccgccag
     5221 cctgcgcgcc gcagcggcga gcgtgccctc gcggccgagg gtgacgagga aacgcagatc
     5281 atcccagttc atcggccgat gctcctgcaa agttgcagca gtgtagagca tgaatgcgca
     5341 tttacgcagg ccggcagccg cctgtaggct gccgccatcg tttctcgaac ccacaaggag
     5401 atcgcccatg agcaccgctt ccatccccct gcgccaactt tccggcctgc ccgccgcacc
     5461 cgcccgcctg tccgagtcgg cgctggtcat cgtcgacgcc cagaacgcct accgcagcgg
     5521 cgtgatgcag ctcgaaggcg tggagccggc cctggacgaa tgcgcccgcc tgctggcgcg
     5581 ggcacgcgcg ctgaagatcc ccgtggtgca catccagcac gatgccggcc ccggctcacc
     5641 ctacgacccc agcgccgaat gcggcgcgat cgccgacaag gtggcaccgg tggccggcga
     5701 ggtggtggtg gtcaagcact acccgaactc cttcgtcggc accgaactcg acgagcgcct
     5761 gaaggccgcg ggggtgaaga acctggtcgt ggtcggcttc atgacccaca tgtgcatcaa
     5821 ctcgaccgcc cgcggcgcct tcaacctcgg ctacgcggtc accgtccccg ccgccgccac
     5881 cgcaacccgc gctctgcccg cgcccgacgg cagcgtggtc gaggccgccg ccctgcaggt
     5941 cgccgcgctc accgcgctcg cagacctgtt cgccgtcgtg gtggccgacg gcgcggccat
     6001 cccggactga gcacccgcaa accgccccgc ccccgggccc gcccacctcg acgaacacgc
     6061 cgcccgcgac gcggcctggc ttcatgtagg agcgccggca ggcgcgaatc gggcgttccc
     6121 a
//
LOCUS       DAOTIN010000166         6043 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_15500_length_6043_cov_8.866733, whole genome shotgun sequence.
ACCESSION   DAOTIN010000166 DAOTIN010000000
VERSION     DAOTIN010000166.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 6043)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 6043)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6043
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_15500_length_6043_cov_8.866733"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(65..1165)
                     /locus_tag="P5537_15730"
     CDS             complement(65..1165)
                     /locus_tag="P5537_15730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV79538.1"
                     /translation="MNFPLDPRMQVAVVDDTQLNLTLIGKLVDRTPNARAHNFERPTP
                     ALEWCLANAPDLIIVDYMMPEMDGLEFIRRIRAHRDRDDLPILMVTASHERDVRYAAL
                     DCGASDFLTKPIDAREFEARVRNMLKLREAHLAGKHRAETLAAEVRRATADILDRERE
                     TITRLSRAAEFRDPETGAHIQRMWHFSALIARRLGLGDAFAEDLLMAAPMHDVGKLGI
                     PDSILLKPGRLTPEEFAVMKRHPQIGHDILKDSSSSILRLGATIALTHHEKFDGSGYP
                     HGLAGESIPIEGRIVAVADVFDALTSARPYKPAWPMSRAVALLREGRGTHFDPACVDA
                     LFHAWDQVLSVQMRYQDEHEPEAPDSPFAPAH"
     gene            complement(1243..2487)
                     /locus_tag="P5537_15735"
     CDS             complement(1243..2487)
                     /locus_tag="P5537_15735"
                     /EC_number="1.13.12.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016703 - oxidoreductase activity, acting
                     on single donors with incorporation of molecular oxygen,
                     incorporation of one atom of oxygen (internal
                     monooxygenases or internal mixed function oxidases)
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitronate monooxygenase"
                     /protein_id="HRV79539.1"
                     /translation="MKRVDDFRLKLGSQELVPIMVGGMGVDISTSDLALEAARLGGVG
                     HISDAMLPTVSDRRYNTKYVKNKLQQYKFNVANADKSVVQFDLGLIAEATATHVSRTM
                     ERKRGPGMVFINCMEKLTMNAPKDTLRVRLRTAMDHGIDGITLAAGLHLGSFALIEDH
                     PRFRDVQLGIIVSSLRALQLFLKKSARTGRMPDYVVVEGPLAGGHLGFGMDWAQYDLA
                     TIVAEIRDWMREQQLDIPLIPAGGIFTGTDAANFLEAGAAAVQVATRFTITKECGLPD
                     EVKQDYFKADEDEIEVNQISPTGYPMRMLKSSPAIGSGIRPNCEAYGYLLDSSGNCQY
                     IEAYNREVAAHPDAKKIKVFDKTCLCTHMRNFDCWTCGHYTYRLKDTTVREEDGDYRI
                     LSAEHVFKDYQFSTEGRIALPE"
     gene            2628..3611
                     /locus_tag="P5537_15740"
     CDS             2628..3611
                     /locus_tag="P5537_15740"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004024 - alcohol dehydrogenase activity,
                     zinc-dependent [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family oxidoreductase"
                     /protein_id="HRV79540.1"
                     /translation="MFKAVLIEKDDAGYRAAVKELDEASLPEGDVGVRVEYSSLNYKD
                     GLAITGRGAVVRKFPMVAGIDLVGTVESSAHPGVAVGDKVILNGWGTSEVHWGGLAQR
                     ARVRGEWLVPLPAAFTPLQAMAIGTAGYTAMLCVMALERHGVVPQRGEVLVTGASGGV
                     GSVAIALLSRLGFTVVASTGRPQEADYLRELGAASIIDRSELGQPGRALGKERWAGVV
                     DTVGSHTLANACATTLYRGTVAACGLAQGLDFPASVAPFILRGVTLVGIDCVMAPREE
                     RIEAWSRLARDLDVGKLERMTREIGLGEVVDTAAALLDGKERGRIVVNVDR"
     gene            3648..4226
                     /locus_tag="P5537_15745"
     CDS             3648..4226
                     /locus_tag="P5537_15745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302438.1"
                     /note="This protein belongs to a clade of uncharacterized
                     proteins related to peroxidases such as the
                     alkylhydroperoxidase AhpD; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peroxidase-related enzyme"
                     /protein_id="HRV79541.1"
                     /translation="MSATISRFKVPELAELAEDVRERILAVQEKAGFVPNVFLMLAHR
                     PAEFRAFFDYHDALMEKDVGLSKAEREMIVVATSAAGQCLYCVIAHGAILRIRAKNPR
                     LADQLATNHRKAEISPRQRAMLDFAIKLSTHGAEVDDADLAALRAHGFDDEAIWDIGA
                     ITAFFSMSNRLVHLTGTPPNDPFYLMGRVPKA"
     gene            4314..4641
                     /gene="ssrA"
                     /locus_tag="P5537_15750"
     tmRNA           4314..4641
                     /gene="ssrA"
                     /locus_tag="P5537_15750"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01850"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="betaproteobacterial-type; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF01850"
     gene            complement(4773..5588)
                     /locus_tag="P5537_15755"
     CDS             complement(4773..5588)
                     /locus_tag="P5537_15755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004370085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibro-slime domain-containing protein"
                     /protein_id="HRV79542.1"
                     /translation="MQVKPLCAALTLLAIASTASAATTTLSGTIRDFCAPSIVDSTGA
                     PVCTQLSDFEGGIPGVVANMTGTNLSGGLPVAGANIVTGASTADNFAKWYVDSPGYNL
                     SQALSLTLNETTPGSGVYSYASSSFFPIDGQLYGNQGRSHNYHFTLHLEGQLSFADPT
                     AGADNSFSFTGDDDLWVFVNGIRFIDLGGVHGAANASFTEETLKAAGLAAGTAYDLDI
                     FFAERHTSESNFNITTTFAIKPPSNDVPEPGGLALLGLGLAGLGALRRRSPGR"
BASE COUNT          963 a         1861 c         2143 g         1076 t
ORIGIN      
        1 gatcgaacgc aaggcctgac gcggggcgtg cccgcgtcgg catgtctggc cccggggccg
       61 ggcctcagtg ggcgggcgcg aacggagagt cgggcgcttc gggttcgtgc tcgtcctgat
      121 agcgcatctg cacggagagc acctggtccc aggcatggaa gagcgcatcc acgcaggcgg
      181 ggtcgaagtg cgtgccgcgg ccctcgcgca gcagcgcgac cgcacgcgac atcggccacg
      241 ctggtttgta gggccgcgcc gaggtgagcg cgtcgaagac gtcggcgacc gcgacgatgc
      301 gcccttcgat cgggatcgac tcgccggcga gtccgtgcgg gtagccgctg ccgtcgaact
      361 tctcgtggtg ggtgagggcg atggtcgcgc ccaagcgcag gatgctcgac gaggagtcct
      421 ttaggatgtc gtggccgatc tgcgggtggc gcttcatcac cgcgaactct tccggcgtca
      481 gccggcccgg cttgagcagg atggagtcgg ggatgccgag cttgccgacg tcgtgcatcg
      541 gcgcggccat cagcaggtct tcggcgaaag cgtcgccgag gccgagtcgg cgcgcgatca
      601 gggcggaaaa atgccacatg cgctggatgt gggcgccggt ctcggggtcg cggaactcgg
      661 cggcgcgtga cagccgggtg atggtctcgc gctcgcggtc gaggatgtcg gccgttgccc
      721 ggcgcacctc ggcggcgagg gtctcggcgc ggtgcttgcc ggcaagatgg gcttcgcgca
      781 gcttgagcat attgcgcacg cgcgcctcga actcgcgcgc atcgatcggc ttggtgagga
      841 aatcgctcgc cccacagtcg agggcggcgt aacgcacgtc gcgctcgtgg ctggcggtca
      901 ccatcaggat gggcaggtcg tcgcggtcgc ggtgcgcgcg gatgcggcgt atgaactcca
      961 gcccgtccat ctccggcatc atgtagtcga cgatgatgag gtcgggcgcg ttggccaggc
     1021 accactcgag cgccggggta gggcgctcga agttgtgggc gcgcgcattg ggcgtgcggt
     1081 cgacgagctt gccgatcagc gtcaggttga gctgcgtgtc atcgaccact gcgacctgca
     1141 tccgaggatc gagtgggaaa ttcatccagt cagtatcggc gtcctcgggg ccggcaccga
     1201 ggaactattg cgcggacgcc gtcgcgtccg cgcatccctg gctcattcgg gcagggcgat
     1261 gcggccttcg gtgctgaact ggtagtcctt gaacacgtgc tcggccgaca ggatgcggta
     1321 gtcgccatct tcttcgcgca ccgtggtgtc cttgagccgg taggtgtagt ggccgcaggt
     1381 ccagcagtcg aagttgcgca tgtgcgtaca gaggcaggtc ttgtcgaaga ccttgatctt
     1441 cttggcgtcg gggtgggccg cgacctcgcg attgtaggcc tcgatgtact ggcagttgcc
     1501 gctggagtcg agcaggtagc cgtaggcctc gcagttgggc cggatgccgc tgccgatcgc
     1561 cgggctgctc ttgagcatgc gcatcggata gccggtgggc gagatctgat tgacctcgat
     1621 ttcgtcttcg tcggccttga agtagtcctg cttgacctcg tcggggaggc cgcactcctt
     1681 ggtgatcgtg aagcgggtcg cgacctggac ggccgcggcg ccggcttcga ggaagttcgc
     1741 cgcgtcggtg ccggtgaaga tgccgccggc ggggatcagc gggatgtcga gctgctgctc
     1801 gcgcatccag tcgcggatct cggcgacgat ggtggcgagg tcgtactgcg cccagtccat
     1861 gccgaagccg aggtggccgc cggcgagcgg gccttcgacg accacgtagt cgggcatgcg
     1921 gccggtgcgt gcgctcttct tgaggaagag ctgcagcgcg cgcagcgagc tgacgatgat
     1981 gccgagctgc acgtcgcgga agcgcgggtg gtcctcgatg agcgcgaacg agcccaggtg
     2041 caggccggcg gccagcgtga tgccgtcgat gccatggtcc atcgcggtgc gcaggcgaac
     2101 gcgcagggtg tccttgggcg cgttcatcgt cagcttttcc atgcagttga tgaacaccat
     2161 gcccggcccg cgcttgcgct ccatggtgcg gctgacgtgg gtcgcggtgg cctccgcgat
     2221 gaggccgagg tcgaactgca ccaccgactt gtcggcgttg gcgacgttga acttgtactg
     2281 ctgcagcttg ttcttgacgt acttggtgtt gtagcgccgg tcggacaccg tcggcagcat
     2341 cgcgtcggag atgtgcccga ccccgcccag ccgggcggcc tcgagcgcca ggtcggaggt
     2401 ggaaatgtcc acccccatcc cgcccaccat gatcggcacg agttcctggg agcccagttt
     2461 caggcggaag tcatctacac gcttcattgc ttggagtccg ttgattcggc agtccgacat
     2521 tatcacccga gagccccctt gcacccaagt tcgagcgcgc ggcggtcatc gtttaacatg
     2581 gggcttcgac tgcaaaaacg gcgcgtggtg cgcccagggg gagaaaaatg ttcaaggcag
     2641 tgctgatcga gaaggatgat gccggctacc gcgcggcggt gaaggagctc gacgaggcct
     2701 cgctgcccga aggcgacgtc ggcgtccggg tggaatattc ctcgctcaac tacaaggacg
     2761 gcctggcgat caccgggcgc ggcgcggtgg tgcgcaagtt tccgatggtg gcgggcatcg
     2821 acctggtcgg cacggtcgag tccagcgcgc acccgggcgt ggcggtgggc gacaaggtca
     2881 tcctcaacgg ctggggcacg agcgaggtgc actggggcgg actggcgcag cgtgcgcgcg
     2941 tgcgcggcga gtggctggtg ccgctgcccg cggccttcac tccgctccag gcgatggcga
     3001 tcgggacggc cggctatacg gcgatgctgt gcgtgatggc gctggagcgc cacggggtcg
     3061 tcccgcagcg cggcgaggtg ctggtcaccg gcgccagcgg tggcgtgggc agcgtggcga
     3121 tcgcgctgct gtcccggctc ggcttcaccg tggtcgcctc caccggccgc ccgcaggagg
     3181 ccgattacct gcgcgaactg ggcgcggcca gcatcatcga ccgcagcgag ctcggccagc
     3241 ccgggcgcgc ccttggcaag gagcgctggg cgggcgtggt cgacaccgtg ggcagccaca
     3301 ccctggccaa cgcctgcgcc accacgctgt accgcggcac ggtcgcggcc tgcggcctgg
     3361 cgcagggcct ggacttcccg gcctcggtcg cacccttcat cctgcgcggc gtcaccctcg
     3421 tcggcatcga ctgcgtgatg gccccgcgcg aggagcgcat cgaggcctgg agccgcctcg
     3481 cccgcgacct cgacgtgggc aagctcgagc gcatgacgcg cgagatcggt ctcggcgagg
     3541 tggtcgatac cgccgccgcg ctgctcgacg gcaaggagcg cgggcgcatc gtcgtcaacg
     3601 tcgatcgctg agcttcatca caagaacatc acaggaggag acttccaatg agcgcaacca
     3661 tcagccgctt caaggtgccc gagctcgcgg agctcgccga ggacgtgcgc gagcgcatcc
     3721 tcgccgtgca ggagaaggcg ggcttcgtgc ccaacgtgtt cctgatgctc gcccaccgtc
     3781 cggccgagtt ccgcgccttc ttcgactatc acgacgctct catggagaag gacgtcggct
     3841 tgagcaaggc cgagcgcgag atgatcgtcg tcgccacctc ggctgccggc cagtgcctgt
     3901 actgcgtcat cgcccatggc gccatcctgc gcatccgtgc gaagaacccg cgtctcgccg
     3961 accagctcgc caccaaccat cgcaaggccg agatcagccc gcgccagcgc gcgatgctcg
     4021 acttcgcgat caagctgagt acgcacgggg ccgaggtcga tgacgccgac cttgcggcgc
     4081 tgcgcgcgca tggcttcgac gacgaggcga tctgggatat cggtgcgatc accgccttct
     4141 tcagcatgag caaccggctg gtgcatctca ccggcacgcc gcccaacgac cccttctacc
     4201 tgatgggtag ggtgccgaag gcgtgaggcg tgaggcgctc gcgggctggg ggcgcgtcgg
     4261 gcggggattt cgcctggcgc ggtgcaattg cttacaaacg gatcgcgcct tctccccacc
     4321 caggcattga atgcggcggc cgacctgcgt aagatcgcgg gcatggttgt aatcccggca
     4381 atctggaggc gttctggaca ggggttcgat tcccctcacc tccacccaag tgcattcggg
     4441 agtgtgcttg ggtgggggtg taccggtttc gacagggcgg gcaaaggtga gcaggcaacc
     4501 cgagaggcga cggacgtaat ccgcgcaaat ccataaacgc caacgatgag cgtttcgcac
     4561 tggccgctta aggcctatgc cgaggctgct tgagccttgt taccaaagaa aagccggtgg
     4621 ggacttcggt ccccatcgtc acgtctacac agccggtttt tgcgcaatcc cgcgcttgcg
     4681 tgcgccgcag cgtccggtgg gtccggaccc tcatgaaaaa acggccaccc ttcgggcggc
     4741 cgtttcggtt tcctgcgcta ccttccccgg gttcagcgcc ccggtgaccg gcgccgcagc
     4801 gcaccaaggc cggcgagtcc aagacccagc agcgcgagtc cgcctggctc cggcacgtcg
     4861 ttcgaaggcg gcttgatcgc gaaggtggtg gtgatgttga agttcgattc gctggtatgg
     4921 cgctcggcga agaagatgtc gaggtcgtag gcggtgccag cggcgaggcc ggcggccttc
     4981 agcgtttcct cggtgaagga ggcgttggcc gcaccatgca cgccgccgag atcgatgaac
     5041 cggatgccgt tcacgaacac ccacagatcg tcgtcgccgg tgaagctgaa ggaattgtcg
     5101 gcaccggcgg tggggtcggc gaaggacagc tggccctcga ggtgcagcgt gaagtggtag
     5161 ttgtggctgc gcccctggtt gccgtagagc tgcccgtcga tcgggaagaa gctcgacgaa
     5221 gcgtacgaat aaacaccgct acccggtgtg gtttcgttca gcgtcagcga caaggcctgg
     5281 ctcaggttgt agcccgggct gtccacgtac cattttgcga agttgtccgc cgtcgaggcg
     5341 ccggtaacga tgtttgcacc ggcaacgggg aggccgccgc tcaggttcgt tccggtcatg
     5401 ttcgccacca ccccggggat gccgccttcg aaatcggaca gttgggtgca caccggagcg
     5461 ccagtgctat cgacgatcga cggtgcgcaa aaatcgcgga tggtcccgga tagggtggtc
     5521 gtcgcggccg aggcggtgga ggcgatcgcc aacagggtga gcgcagcgca gagaggtttg
     5581 acttgcatga tcttcactcc tttcggatcc cgagcaacat ttccggcgtt cgggggttcg
     5641 aagagtgtca agcaaatgct gtgcctactt tgtggtggtg atggcaagtg tatgaaaagt
     5701 atggattagt gcagattcgt gacttgatcg gcgagtgcac tttggtcggg attgtaaaaa
     5761 tcgccgacag gggctcgatc ggcggcgcaa tcctcgcgcg ccacgaacgc gtgccgggtc
     5821 tgcggatccc cgcgatggct cgatggattc gacgcgatcg cttctcatgt cgatcaacgg
     5881 gcgggaatcg acaggtggta cggatgccgt cgtccctaag gtgctccgtt cgtcgccctg
     5941 ctttcgccag gcaatgaaaa ggggcccagg atttctcctg agccccggat tccattggtg
     6001 ggccctgcgg gattcgaacc cgcaaccaaa ggattatgag tcc
//
LOCUS       DAOTIN010000167         6039 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_15514_length_6039_cov_8.573697, whole genome shotgun sequence.
ACCESSION   DAOTIN010000167 DAOTIN010000000
VERSION     DAOTIN010000167.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 6039)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 6039)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6039
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_15514_length_6039_cov_8.573697"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(193..759)
                     /locus_tag="P5537_15760"
     CDS             complement(193..759)
                     /locus_tag="P5537_15760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004316714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase D family protein"
                     /protein_id="HRV79543.1"
                     /translation="MLGWMAALALVAAPALPGVQASERFAGKGEIELAFSPRDDTEKV
                     VISLIRSARKTLEVHAYAFTSRNIADAMVAAQRRGVRVEVLADAQMNRREKGNAIPRL
                     LAAGVPVAFETRYNAAHNKVLIVDAEGPRCAVLTGSYNFTWSADNRNAENILIVRDHC
                     ELARAYRSNWLRHRKEATRITSLPWRER"
     gene            complement(881..2218)
                     /locus_tag="P5537_15765"
     CDS             complement(881..2218)
                     /locus_tag="P5537_15765"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004383912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HRV79544.1"
                     /translation="MKPKTEKNRVRKPQEPSPAERPAEGAVSRTLFIQATQALGAVLA
                     FDHPADAVLSRHFRDNRELGHRDRGFIAEAVYGVLRRLRWLRRIAGAEATPRMLLLAW
                     FARGEGWPMRNFEGLASATERDWITSIKAAEAGEPSLAERADLPDWLAERLLAQMSED
                     ELIALAHGLNRPAPLDLRANLVKTDRDALLERLQADGVRAEPGRLSPQSIRLAGKPAL
                     QKHPLFLDGSFEVQDEGSQLLGLLVQPRRGELVVDFCAGAGGKTLQLGAMMRSTGRLY
                     AFDVSEKRLAKLKPRMARAGLSNVHPVLIAHEADAKVKRLAGKADRVLVDAPCTGLGT
                     LRRNPDLKWRQSPAAVEEMVAKQGAILAAAARLVRPGGRLVYATCSLLAEENDGIVDA
                     FLAAHPEFRTQSAQEVLAAQGVTLETGERLRLLPHEHDTDGFFAAVMERAKGA"
     gene            complement(2220..2963)
                     /locus_tag="P5537_15770"
     CDS             complement(2220..2963)
                     /locus_tag="P5537_15770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3108 domain-containing protein"
                     /protein_id="HRV79545.1"
                     /translation="MRALLARLALTACASLAALPAGAAAEPAAQGHILYDVHYGSSGF
                     KVGEARHDWKLEEGRYALTLALQAKGLAGLFGLEYEQRSSGTVDAKGLRPVLFEVDQR
                     GRKPERAEFDWAKGRVSIRRGGEERRSGEIRAGDQDLLSLWHQARKVAESGKPARFAV
                     VTNKSIKQAVVEPRGEERLELAGEQLDTVRLHAFAEKDDLDIDIWLSRRHGLLPVRIR
                     ITDDKGGVLDQRASRIEAGAAATAARNPN"
     gene            complement(2963..3619)
                     /gene="purN"
                     /locus_tag="P5537_15775"
     CDS             complement(2963..3619)
                     /gene="purN"
                     /locus_tag="P5537_15775"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004374902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HRV79546.1"
                     /translation="MKSIVILISGRGSNMEAIVRAGIPGARIAAVISNRPGAGGLEFA
                     RTHGIATAVVDHKSHPDRASFDEALAVCIDAHAPDLVVLAGFMRVLTDAFVRRYEGRL
                     LNIHPSLLPSFPGLHTHRRALETGVKVHGASVHFVTAELDDGPIVIQAAVPVLAGDDE
                     DALAARVLAQEHRIYPQAVRWFVEDRLELGGGRVSLRDAPAQAGEALLVPAPETAGRV
                     "
     assembly_gap    4106..4205
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            4534..>6039
                     /gene="mutL"
                     /locus_tag="P5537_15780"
     CDS             4534..>6039
                     /gene="mutL"
                     /locus_tag="P5537_15780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HRV79547.1"
                     /translation="MPHIHRLSDLLVNQIAAGEVVERPASVLKEVLENAVDAGARAIE
                     VQLEQGGVRRIRVADDGCGIARDELALALERHATSKIATLDDLEHVGTMGFRGEALAA
                     IAAVARTSITSRADGASHAWRIEAGRQPEPAALDQGSVVDVADLYYNTPARRKFLKTE
                     ATEFAHCDDMFRRVALARPDIGLQLAHNGRVIHRLPPSPPAARVAALMGDDFLQHARE
                     VQADAGVLRLAGFASLPAYSRASRDAQYFFVNGRFVRDKLLAHAVREAYADILHGARH
                     PAYVLFLELDPAGVDVNVHPAKIEVRFRESRAVHQFVFHAVRRTLAESGAGRAAEGAG
                     PAAMGAAADAGPGSGAGALQASPASSAVPQAGFGGVAPPLAMTAGAQPASRSWPPAHA
                     QQGRLAMESASRAYFDFAAGAREAGAAGLPGRSAERPAGTHPAFAETPAGEAPPLGYA
                     LGQLHGIYILAQNAAGLVLVDMHAAHERILYEKLKTVIDGRPAVQRLLIPAV"
BASE COUNT          774 a         2187 c         2119 g          859 t
ORIGIN      
        1 gcagccgcga acggggcctg cgggatggcg acgtggccgc ttgccgcgcc gccgccttcg
       61 cgcctgccgg cgctcctaca tgaaccgtcg cgacgcgccc gcgcctcgtg taggagcggc
      121 ggcagccgcg aacggggcct gcgcaagggc gacgtggcca cttgccgctc cgccgccttc
      181 gcgcctgcag ggtcatctct cgcgccatgg cagggacgtg atccgggtcg cctccttgcg
      241 gtggcgcagc cagttggagc ggtaggcacg cgcgagctcg cagtggtcgc gcacgatgag
      301 gatgttctcg gcgttgcggt tgtccgccga ccaggtgaag ttgtacgagc cggtgagcac
      361 cgcgcagcgc gggccttcgg cgtctacgat cagcaccttg ttgtgcgccg cgttgtagcg
      421 cgtctcgaag gctaccggca cgccggctgc gagcaggcgc gggatggcgt tgcccttctc
      481 gcggcggttc atctgcgcgt cggcgagcac ctcgacgcgc accccgcgcc gctgcgccgc
      541 gaccatcgcg tcggcgatgt tgcggctggt gaaggcgtag gcgtgcacct ccagggtctt
      601 gcgcgcactg cgtatgaggc tgatcaccac cttctcggtg tcgtcccgcg gcgaaaaggc
      661 gagctcgatc tctcccttgc ccgcgaagcg ctcgctcgcc tgcacgcccg ggagcgccgg
      721 cgccgccacg agggcgagcg ccgccatcca gccgagcatc gacgcgcagc gcctgcgagt
      781 ccgctcacgc tcccgctgct cgaccggctc gccgatttgc tcgtcgaccc gcttgtccat
      841 gcacagggcc atccgctcct cgacccgctt gcccggccgc tcacgcaccc ttggcgcgct
      901 ccatcaccgc ggcgaagaag ccgtcggtgt cgtgctcatg cggcagcagg cgcaaacgct
      961 cgccggtctc cagcgtcacg ccctgggctg ccagcacctc ctgcgccgac tgcgtgcgga
     1021 actcggggtg cgcggcgagg aaggcgtcga cgatgccgtc gttctcctcg gcgagcaggc
     1081 tgcaggtggc atacaccagg cgtccgcccg gacgcaccag gcgcgccgct gcggcgagga
     1141 tcgcaccctg cttggcgacc atctcctcga ccgctgccgg cgactggcgc cacttgaggt
     1201 cggggttgcg gcgcaaggtg cccagcccgg tgcagggcgc atcgaccagc acgcggtcgg
     1261 ccttgcccgc caggcgcttg accttggcat cggcctcgtg cgcgatcagc accggatgca
     1321 cgttcgacag gccggcgcgc gccatgcgcg gcttgagctt ggcgaggcgc ttctcggaga
     1381 cgtcgaaggc gtacaggcgc ccggtcgagc gcatcatcgc gcccagctgc agggtcttgc
     1441 cgccggcgcc ggcgcagaag tccaccacca gctcgccgcg gcgcggctgc accagcaggc
     1501 cgagcagctg gctgccctcg tcctgcacct cgaagctgcc gtcgaggaac agcggatgct
     1561 tctgcagcgc cggcttgccc gcgagccgga tcgattgcgg cgacagccgg ccgggctcgg
     1621 cgcgcacgcc gtcggcctgc aggcgctcga gcagcgcgtc gcggtcggtc ttgaccaggt
     1681 tcgcccgcag atcgagcggc gccggacggt tgagcccgtg cgcgagcgcg atcagctcgt
     1741 cctcgctcat ctgcgccagc aggcgctcgg ccagccagtc gggcaggtcg gcacgctcgg
     1801 ccaggctggg ctcgcccgcc tcggcggcct tgatcgaagt gatccagtcg cgctcggtgg
     1861 cgctcgccag tccctcgaag ttacgcatcg gccagccctc gccgcgcgcg aaccaggcca
     1921 gcaacagcat gcgcggggtg gcctcggcgc cggcgatgcg gcgcagccag cgcagccggc
     1981 gcagcacgcc atacaccgcc tcggcgatga agccgcggtc gcggtggcca agctcgcggt
     2041 tgtcacggaa gtggcgcgac agcacggcgt cggccggatg gtcgaaggcg agcacggcgc
     2101 cgagcgcctg cgtggcctgg atgaagagcg tgcgcgacac cgcgccctcc gcggggcgct
     2161 cggccgggct cggctcctgc ggcttgcgca cgcggttctt ttcggtcttg ggtttcattt
     2221 cagttcgggt tcctggcggc ggtggcggct gcgcccgcct cgatgcgcga ggcgcgctgg
     2281 tcgagcacgc cgcccttgtc gtcggtgatg cggatacgga ccggcagcag gccgtggcgc
     2341 ctggacagcc agatgtcgat gtcgaggtcg tccttctcgg cgaaggcgtg caggcgcacg
     2401 gtgtcgagtt gctcgccggc gagctcgagg cgctcctcgc cgcgcggctc caccaccgcc
     2461 tgcttgatgc tcttgttggt gaccacggcg aagcgcgccg gcttgccgga ctcggccacc
     2521 ttgcgcgcct ggtgccacag gctcagcagg tcctggtcgc cggcgcggat ctctccgctg
     2581 cgccgctcct cgccgccgcg gcggatgctg acccggccct ttgcccagtc gaactcggcg
     2641 cgctcgggct tgcgcccgcg ctggtcgacc tcgaacagca ccggacgcaa gcccttggcg
     2701 tccaccgtgc cgctgctgcg ctgctcgtac tccaggccga acagcccggc gagccccttg
     2761 gcctgaagcg ccagcgtgag tgcgtagcgg ccttcttcca gcttccagtc gtggcgcgcc
     2821 tcgcccacct tgaagccgga cgagccgtag tgcacgtcgt agaggatgtg tccttgcgcg
     2881 gccggctcgg cagccgcgcc ggcgggcagc gccgccaggc tcgcgcaggc ggtgagcgcg
     2941 aggcgcgcga gcagcgcgcg catcagaccc gccccgcggt ctcgggcgcc ggcaccagca
     3001 gcgcctcacc ggcctgcgcc ggcgcgtcgc gcaggctcac ccggccgccg ccgagctcga
     3061 gccggtcctc gacgaaccag cgcaccgcct gggggtagat gcggtgctcc tgcgcgagca
     3121 cgcgtgcagc cagtgcgtcc tcgtcgtcgc cagccagcac cggaaccgcg gcctggatca
     3181 cgatcgggcc gtcatcgagc tcggcggtga cgaaatgcac gctcgcgcca tgcaccttca
     3241 ccccggtctc gagcgcgcgg cggtgggtgt gcagcccggg gaaggacggc agcagcgagg
     3301 gatggatgtt gagcaggcgg ccttcgtagc ggcgcacgaa ggcgtcggtg agcacgcgca
     3361 tgaagccggc gagcacgacc agatcgggcg catgggcgtc gatgcacacg gcgagcgcct
     3421 cgtcgaagct ggcgcggtcg gggtgggact tgtggtcgac caccgcggtg gcgatgccgt
     3481 gcgtgcgcgc gaactcgagt ccgcccgcgc ccggccggtt gctgatcacc gcggcgatgc
     3541 gcgcgccggg gatgccggcg cgcacgatgg cttccatgtt gctgccgcgg ccggagatga
     3601 ggatgacgat ggacttcatg ggatgctggg acgatgaaag atcttggcgg aggaccgggc
     3661 gtcggcgtgt ggaccgccgg gcgcccaccc cggaacatgg ccgcgatgat acccgacccg
     3721 cgccaggctc ccggcgcgga tcgggaaaat cagcggtttt tgcagccgcg aagctggcct
     3781 gcttcgtcgc ccgagccggg atctgcggcg ctgcattcgc gcctgccggc gctcctacat
     3841 gaaccggcac gcttgcgtcc gaggtggcgc tgcattcgtg cctggcggcg ctccacacat
     3901 gaaaccggcg caggttcggt ccggaaacgg gcgatcggcc atcggcgcgc gttgattccg
     3961 gccccggcgc ctccgcacgc acctgtagga gcgccggcag gcgcgaatcg ggcggtcggg
     4021 cgatcgacgt gcgtcgaaat ctccaacgcc gcattcgcgc ctgccggcgc tcctacatga
     4081 accggcacgc ttgcgtccga ggtggnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4141 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4201 nnnnncatga aaccggcgca ggttcggtcc ggaaacgggc gatcggccat cggcgcgcgt
     4261 cgattccggc cccggcgcct ccgcaagcac ctgtaggagc gccggcaggc gcgaatgggc
     4321 ggtgacggag cgatgagcgt aggtagggat tgtgccgcct tgttcgcgcc tgccggcgct
     4381 cctacatgaa ccgacgcgtt tccggagcct tgtgggcgct cctaagtgaa cgtcatggtt
     4441 gcgtccgagg caggagaggt tgcgggcgcg cagcccggcg tgccgcctcc cctgccccgt
     4501 ataatcctgc ttttgcctga cggccgccgc cccatgcccc acatccaccg cctctccgac
     4561 ctgctggtca accagatcgc cgccggcgag gtggtcgagc gcccggcctc ggtgctcaag
     4621 gaggtgctcg agaacgcggt cgatgcgggc gcgcgcgcga tcgaggtgca gctcgagcag
     4681 ggcggcgtgc gccgcatccg cgtcgccgac gacggctgcg gcatcgcgcg tgacgagctc
     4741 gcgctcgcgc tcgagcgcca cgccaccagc aagatcgcca ccctcgacga tctcgagcac
     4801 gtgggcacga tgggctttcg tggcgaggcg ctggccgcga tcgccgcggt ggcacgcacc
     4861 agcatcacca gccgcgccga cggtgcgagc cacgcctggc gcatcgaggc agggcgtcag
     4921 cccgagccgg cggcgctcga ccagggcagc gtggtcgacg tcgccgacct ctactacaac
     4981 acccccgcgc ggcggaagtt tctcaagacc gaggccaccg agttcgccca ctgcgacgac
     5041 atgttccgcc gcgtcgcgct cgcgcgcccg gacatcggcc tgcagctcgc ccacaacggc
     5101 cgcgtgatcc accgcctgcc gccctcgccg ccggcggcgc gcgtcgccgc gctgatgggc
     5161 gacgacttcc tgcagcacgc ccgcgaggtc caggccgacg ccggcgtgct gcgcctggcc
     5221 ggcttcgctt ccctgcccgc ttactcgcgc gccagccgcg acgcgcagta tttcttcgtc
     5281 aatggccgct tcgtgcgcga caagctgctc gcccacgcgg tgcgcgaggc ctacgccgac
     5341 atcctgcacg gcgcgcgcca ccctgcctac gtgctcttcc tcgagctcga ccccgccggg
     5401 gtggatgtga acgtgcatcc ggccaagatc gaggtgcgct tccgcgagtc gcgcgcggtg
     5461 catcagttcg tcttccacgc cgtgcgccgc acgctggccg agagcggggc gggacgcgcg
     5521 gcggaggggg ccgggcccgc ggccatggga gcagctgcgg atgccggccc aggttcagga
     5581 gccggcgcgc tgcaggcctc gccggcatcg agcgcggtcc cgcaagcggg cttcgggggc
     5641 gtcgcccccc cgctcgccat gacggccggc gcccaaccgg cctcgcggtc ctggccgccc
     5701 gcccacgccc agcagggacg cctggcgatg gagtcggcga gccgcgccta cttcgatttc
     5761 gccgcgggcg cgcgcgaagc gggcgccgcc ggcctgcccg gccgatccgc cgaacgcccc
     5821 gcgggcaccc accctgcgtt cgcggaaacg cccgcgggcg aggcgccgcc gctcggctac
     5881 gcgctcggcc agttgcacgg catctacatc ctcgcccaga acgccgccgg cctcgtgctg
     5941 gtggacatgc acgccgccca cgagcgcatc ctctacgaga agctcaagac cgtgatcgac
     6001 ggccgcccgg cggtgcagcg cctgctgatc ccggcggtg
//
LOCUS       DAOTIN010000168         5981 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_15746_length_5981_cov_8.125042, whole genome shotgun sequence.
ACCESSION   DAOTIN010000168 DAOTIN010000000
VERSION     DAOTIN010000168.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 5981)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5981)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5981
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_15746_length_5981_cov_8.125042"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1152
                     /locus_tag="P5537_15785"
     CDS             <1..1152
                     /locus_tag="P5537_15785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase subunit alpha"
                     /protein_id="HRV79548.1"
                     /translation="ARFSGQPEYVVNYFFFVAEEVRELMAQLGVRTFDELIGRADLLD
                     MKKGIAHWKAQGLDYSRIFYLPNVPAEVPRLHSETQDHGLDKALDRQLVALAKPALEK
                     GEKVNIDLPVRNINRTVGAMLSGEVAKRYGHAGLPNDTIHIRLNGTAGQSFGAFVARG
                     VTLELVGEGNDYVGKGLSGGRIIVRPKAEFRGDTPQNIIVGNTVLYGATEGEVYFAGV
                     AGERFAVRNSGATAVVEGVGDHGCEYMTGGTVVVLGQTGRNFAAGMSGGVAYVLDEDG
                     TFEQRCNMAQVALEPLPDEIAARKGSESGDELESHGRVDIDHLTMGDELILKGLIERH
                     VRFAGSVRAREILNNWGVWRKKFVKVFPHEYRRALTEMAQQREAEKEAA"
     gene            1153..>2385
                     /locus_tag="P5537_15790"
     CDS             1153..>2385
                     /locus_tag="P5537_15790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase subunit beta"
                     /protein_id="HRV79549.1"
                     /translation="MGKPTGFMEYQRLSEAYEPVDKRLKTYKEFVVRLTDEQASVQGA
                     RCMDCGIPFCNNGCPVNNIIPDWNDLVYRGHWREAIEVLHSTNNFPEFTGRICPAPCE
                     AACTLNINADAVGIKSIEHAIIDKAWEEGWVVPQPAEVSTGRKVAVVGSGPAGLAAAQ
                     QLARAGHDVTVFEKNDRIGGLLRYGIPDFKMEKSLIDRRVEQLQAEGVVFRTGVLVGA
                     ASVPAGIVNDAKQLISAEQLQQDFDAVVLAGGSEIPRDLPVPGRELGGVHYALEFLIP
                     QNKQVAGDKPNPISAKGKHVVVIGGGDTGSDCVGTSNRHGAASVTQFELMPMPPEQEN
                     KALTWPYWPTKLRTSSSHEEGCERDFAVATKEFIGKNGKVKALKACRLEFKDGKMSEV
                     AGSEFEIKADLVLFAMGFT"
     assembly_gap    2386..2485
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            2716..3153
                     /gene="aroQ"
                     /locus_tag="P5537_15795"
     CDS             2716..3153
                     /gene="aroQ"
                     /locus_tag="P5537_15795"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II 3-dehydroquinate dehydratase"
                     /protein_id="HRV79550.1"
                     /translation="MPKVLVINGPNLNLLGTREPEIYGATTLADVEHALRAQGEALGI
                     ELSCFQSNHEGAIVDRIHAARTEGVAWILINPGAYTHTSVAIRDALAGVAIPFVEVHI
                     SNVHKREPFRHHSYLSDVAEAVMAGFGVHGYGLALQYIAIRLG"
     gene            3176..3928
                     /locus_tag="P5537_15800"
     CDS             3176..3928
                     /locus_tag="P5537_15800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HRV79551.1"
                     /translation="MDALGWFVTAIAILLTGISKAGLGGALGGLAVPFMSMWIPPRDA
                     VAVVLPILIVMDMVGIRVWRGKADRGDLRHLIPAALLGIGAGTLLFGVLSDRMVKLVL
                     GLIALAFVADRLLRRRAEAAAPGERSRAPAFAWLCGAGAGFTSTLAHAGGPPIMAYLL
                     SRGLPKERFVATSVFFFTAINLAKLPFYLGIGLFSRDTLLMSAMLLPLVPVGVWLGLH
                     LLRRIPERPFFLFATWALALSGAKLLWDGLAG"
     gene            complement(4120..5862)
                     /gene="ggt"
                     /locus_tag="P5537_15805"
     CDS             complement(4120..5862)
                     /gene="ggt"
                     /locus_tag="P5537_15805"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HRV79552.1"
                     /translation="MKTTRTLLATAVMMAAFGALAKQPVDTGHGGAVATISHEASLAA
                     MQILDAGGNAIDAAVAAAATLGVTDPFSCGIGGGGFMLIWSAKDKRVIAIDHREVAPA
                     SFHPGVFLDAAGKEMDWKATVPNGISVGVPGTVRGWHEALTRYGTMSLDKVLAPAIRV
                     AEQGFAVGPNFHRINKVNEAKFARFSTASALYLQDGKALPVGTHFRNPDLAQTYRDLA
                     RGGVKAFYEGPIAASMVAAVNHPPVNAGVSVIAGDLTMADLKDYEARIRPPVRSTYRG
                     YEVYGMPAPSSGGIAIAQALNLLETFDLADKPRAEIEHLYLEASRLAFADRNAYVADE
                     EFVDIPKDGLLSKEYARERARRIGSGAAPGKVAAGDPYPFEDDRSVPLRPQPRPLAQE
                     SMHTTHLAVSDRDGNVVAYTFTIEDWGGSGIVVPGRGFLLNNELTDFDFSGPHPNLPE
                     AFKRPRSSMSPTIVVKDGAPAFTIGSPGGSTIITTALQTIVNHVDLGMSLADALAAPR
                     MSQRNGDTTLVETLLGFPGSEQAKALEAKGHKWRETDQIGAANGIRFNADGTVTAVSE
                     PVRHGGGSAIVQKQ"
BASE COUNT          864 a         2034 c         2073 g          910 t
ORIGIN      
        1 gcgcgcttct ccggccagcc cgagtacgtg gtcaactact tcttcttcgt cgccgaggaa
       61 gtgcgcgagc tcatggcgca actgggcgtg cggaccttcg acgagctcat cggccgcgcc
      121 gacctgctcg acatgaagaa gggcatcgcg cactggaagg cgcagggcct ggactactcg
      181 cgcatcttct acctgcccaa cgtgcccgcc gaggtgccgc gcctgcacag cgagacgcag
      241 gaccacggcc tcgacaaggc gctcgaccgc cagctcgtcg cgctcgccaa gccggcgctg
      301 gagaagggcg agaaggtcaa catcgacctg ccggtgcgca acatcaaccg caccgtgggc
      361 gcgatgctct cgggcgaggt ggccaagcgc tacggccacg ccggcctgcc caacgacacc
      421 atccacatcc gcctgaacgg caccgccggc cagagcttcg gcgccttcgt ggcgcgcggc
      481 gtcaccctcg agctggtggg cgagggcaac gactacgtcg gcaagggtct gtcgggcggc
      541 cgcatcatcg tgcgcccgaa ggccgagttc cgtggcgaca cgccgcagaa catcatcgtc
      601 ggcaacaccg tgctctatgg cgcgaccgag ggcgaggtct actttgccgg cgtcgcgggc
      661 gagcgcttcg cggtgcgcaa ctccggcgcc accgcggtgg tggaaggcgt gggcgaccac
      721 ggctgcgagt acatgaccgg cggcaccgtg gtggtgctcg gccagaccgg gcgcaacttc
      781 gccgccggca tgtcgggcgg cgtggcctac gtgctcgacg aggacggcac gttcgagcag
      841 cgctgcaaca tggcgcaggt cgcgctcgag ccgctgcccg acgagatcgc cgcgcgcaag
      901 ggctcggagt cgggcgacga gctcgagtcc cacggccgcg tcgacatcga ccacctgacg
      961 atgggcgacg agctcatcct gaagggcctg atcgagcgcc acgtccgctt cgccggcagc
     1021 gtgcgcgcgc gcgagatcct gaacaactgg ggcgtctggc ggaagaagtt cgtcaaggtg
     1081 ttcccgcacg agtaccgccg cgcgctgacc gagatggcac agcagcgcga agctgagaag
     1141 gaggccgcat aaatgggcaa gcccaccgga ttcatggaat atcagcgtct gtccgaggcc
     1201 tacgagccgg tcgacaagcg cctgaagacc tacaaggagt tcgtcgtccg cctcaccgac
     1261 gagcaggcgt cggtgcaggg cgcgcgctgc atggactgcg gcatcccgtt ctgcaacaac
     1321 ggctgcccgg tcaacaacat catcccggac tggaacgacc tcgtgtatcg cggccactgg
     1381 cgcgaggcga tcgaggtgct gcactcgacc aacaacttcc ccgagttcac cggccgcatc
     1441 tgccccgcgc cctgcgaggc ggcgtgcacg ctgaacatca acgccgacgc ggtgggcatc
     1501 aagtcgatcg agcacgcgat catcgacaag gcctgggaag agggctgggt ggtgccgcag
     1561 ccggccgaag tcagcacggg ccggaaggtc gccgtggtcg gctccggccc ggcggggctg
     1621 gccgccgcgc agcaacttgc gcgcgccggc cacgacgtca ccgtgttcga gaagaacgac
     1681 cgcatcggcg gcctgctgcg ctacggcatc cccgacttca agatggagaa gtcgctgatc
     1741 gaccgccgcg tcgagcagct ccaggccgag ggcgtggtgt tccgtaccgg cgtgctggtc
     1801 ggcgccgcca gcgtgcccgc cggcatcgtc aatgatgcga agcaactgat cagcgccgag
     1861 cagctgcagc aggacttcga cgccgtcgtg ctcgccggcg gctccgagat cccgcgcgac
     1921 ctgccggtgc ccggccgcga gctcggtggc gtgcattacg cgctcgagtt cctgatcccg
     1981 cagaacaagc aggtcgccgg cgacaagccc aacccgatct cggccaaggg caagcacgtg
     2041 gtggtgatcg gcggtggcga caccggctcc gactgcgtcg gcacctcgaa ccgccacggc
     2101 gcggccagcg tgacccagtt cgagctcatg ccgatgccgc ccgagcagga gaacaaggcg
     2161 ctcacctggc cgtactggcc gaccaagctg cgcacctcgt cctcgcacga ggagggctgc
     2221 gagcgtgact tcgccgtcgc caccaaggag ttcatcggca agaacggcaa ggtcaaggcg
     2281 ctcaaggcct gtcgactgga gttcaaggac ggcaagatgt ccgaggtggc gggctcggag
     2341 ttcgagatca aggccgacct ggtgctgttc gcgatgggct tcaccnnnnn nnnnnnnnnn
     2401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2461 nnnnnnnnnn nnnnnnnnnn nnnnngagag cctgctgccg cgctgattgc acctgagacc
     2521 acgccgccgc ggcagcaggt ttcatgcgcg gcgacggttc gcggcttccg ccgctcctac
     2581 aggaaccgac gcgagcttca tgtaggagcg gcggaagccg cgaacttttc tggcatcctc
     2641 tgcgctgaag cgatttgcga aaggcggtcc gcggaccgcc ttttttacga ccctgtctcc
     2701 cggagcgcgc catccatgcc caaggtcctc gtcatcaacg gccccaacct caatctgctc
     2761 ggcacccgcg agcccgagat ctacggcgcg accacgctcg ccgacgtcga gcacgccctg
     2821 cgcgcgcagg gcgaggcgct cggcatcgag ctgtcgtgtt tccagagcaa ccacgagggc
     2881 gcgatcgtcg atcgcatcca cgccgcgcgc acggaaggcg tggcctggat cctcatcaac
     2941 ccgggcgcct acacccacac cagcgtggcg atccgcgacg cgctcgccgg ggtggcgatt
     3001 cccttcgtcg aagtgcacat ctccaacgtg cacaagcgcg agcccttccg ccaccactcc
     3061 tacctgtccg acgtcgccga ggcggtgatg gccggtttcg gcgtgcacgg ctacggcctg
     3121 gcgctgcagt acatcgccat ccgcctgggc tgacctcacc cgtgcccgcc gcgtgatgga
     3181 cgccctcggc tggttcgtca ccgccatcgc catcctgctc accggcatct ccaaggccgg
     3241 gctgggcggg gcgctcggcg ggctcgcggt gcctttcatg tcgatgtgga tcccgccgcg
     3301 ggacgcggtc gcggtggtgc tgccgatcct catcgtgatg gacatggtgg gcatccgggt
     3361 gtggcggggc aaggccgacc ggggcgacct gcgccacctg atcccggctg cgctgctggg
     3421 catcggcgcg ggcacgctgc tcttcggcgt gctctccgac cgcatggtca agctcgtgct
     3481 cgggctgatc gcgctcgcct tcgtcgccga ccgcctgctg cgccggcgcg ccgaggccgc
     3541 agcgcccggc gagcgctcgc gtgcgccggc cttcgcctgg ctgtgcggcg ccggcgccgg
     3601 cttcaccagc acgctcgcac acgccggcgg cccgccgatc atggcctacc tgctgtcccg
     3661 cggcctgccc aaggagcgct tcgtcgccac ctcggtgttc ttcttcaccg cgatcaacct
     3721 cgccaagctg cccttctacc tcggcatcgg cctgttcagc cgcgacaccc tgctgatgtc
     3781 ggcgatgctg ctgccgctgg tcccggtggg cgtctggctc ggcctgcatc tgctgcgccg
     3841 catccccgag cgtcccttct tcctgttcgc cacctgggcg ctcgcgctgt ccggggccaa
     3901 gctgctgtgg gacgggctgg cgggctgagc accgcggcga tataaagacg gtggaggttc
     3961 gcgcctgccg gcgctcctac agcaaccgac gcggcttcga ccccgtgcag gagcgccggc
     4021 aggcacgaat gccctggcgg gccgggtccg atccaccgcg ccggcaggtc attgccccgc
     4081 cccggaatct ctctcgccga ggcgggtcaa atgggccgct tactgcttct gcacgatcgc
     4141 gctgccgccg ccgtggcgca cgggctcgct gaccgcggtc accgtgccgt cggcgttgaa
     4201 gcggatgccg ttggcggcgc cgatctggtc ggtctcgcgc cacttgtggc ccttcgcctc
     4261 cagcgccttg gcctgctcgc tgccggggaa gcccagcagg gtctccacca gcgtggtgtc
     4321 gccgttgcgc tggctcatgc gcggcgcggc gagcgcgtcg gccaggctca tgcccaggtc
     4381 gacgtgattg acgatggtct gcagcgcggt ggtgatgatg gtcgagccgc ccggcgagcc
     4441 gatggtgaac gccggcgcgc cgtccttcac cacgatggtc gggctcatgc tcgagcgcgg
     4501 gcgcttgaag gcctcgggca ggttcgggtg ggggccgctg aagtcgaagt cggtgagctc
     4561 gttgttgagc aggaagccgc gccccggcac cacgatgccg ctgccgcccc agtcctcgat
     4621 ggtgaaggtg taggcgacca cgttgccgtc gcggtcggac accgcgaggt gggtggtgtg
     4681 catcgactcc tgcgcgagcg gcctgggctg cgggcgcagc ggcaccgagc ggtcgtcctc
     4741 gaaggggtag gggtcgcccg ccgcgacctt gccgggcgcc gcgccggagc cgatccgtcg
     4801 cgcgcgctcg cgggcgtact ccttggacag gagaccgtcc ttggggatgt ccacgaactc
     4861 ctcgtcggcc acgtaggcat tgcggtcggc gaaggccagg cgcgaggcct cgaggtagag
     4921 gtgctcgatc tcggcgcgcg gcttgtccgc gaggtcgaag gtctcgagca ggttgagcgc
     4981 ctgcgcgatc gcgataccgc cgctggacgg cgcgggcatg ccgtagacct cgtagccgcg
     5041 gtaggtcgag cgcaccggcg ggcggatgcg cgcctcgtag tccttgaggt cggccatggt
     5101 gaggtcgccg gcgatcacgc tgacgcccgc attgaccggc gggtggttca cggccgccac
     5161 catgctcgca gcgatcggcc cctcgtagaa ggccttgacc ccgccgcgcg cgaggtcgcg
     5221 gtaggtctgc gcgagatccg ggttgcggaa gtgcgtgccc accggcagcg ccttgccgtc
     5281 ctgcaggtag agcgccgagg cggtggagaa gcgtgcgaac ttggcctcgt tgaccttgtt
     5341 gatgcggtgg aagttgggcc cgaccgcaaa gccctgctcg gcgacgcgga tggcgggggc
     5401 gagcaccttg tccaggctca tcgtgccgta gcgcgtcagc gcctcgtgcc agccgcgcac
     5461 cgtgccgggc acgccgaccg agatgccgtt gggcacggtg gccttccagt ccatctcctt
     5521 gcctgcggcg tcgaggaaga cgccggggtg gaagctcgcc ggggcgacct cgcggtggtc
     5581 gatggcgatc acgcgcttgt ccttggcgga ccagatgagc atgaagccgc cgccgccgat
     5641 gccgcagctg aacgggtcgg tgacgccgag cgtggccgcc gcggccaccg cggcgtcgat
     5701 ggcgttgccg ccggcatcga ggatctgcat cgcggccagg ctggcctcgt gcgagatggt
     5761 ggcgaccgcg ccgccgtggc cggtgtcgac cggctgcttc gccagggcgc cgaaggcggc
     5821 catcatgacc gcggtggcga ggagggtgcg tgtcgttttc atgatgcgct ccgtcggggt
     5881 ggggacatga cggtagcaca gggcggccgg ttcgcggctg ccgccgctcc tacaggatcc
     5941 gggaggcgcg atggttctgt aggagcgccg gcaggcgcga a
//
LOCUS       DAOTIN010000169         5911 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_16000_length_5911_cov_9.031250, whole genome shotgun sequence.
ACCESSION   DAOTIN010000169 DAOTIN010000000
VERSION     DAOTIN010000169.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 5911)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5911)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5911
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_16000_length_5911_cov_9.031250"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(2..880)
                     /locus_tag="P5537_15810"
     CDS             complement(2..880)
                     /locus_tag="P5537_15810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HRV79553.1"
                     /translation="MKRILIVGSGDVARRALPWLLRRFRVFALVRQPEAAVELRALGA
                     VPVVGDLDDRQSLRRLAGIADAVLHFAPPPQTGHGDPRMARLLAALAGRSSLPQGVVY
                     ISTTGVYGDCAGGRVDETRPCRAQTARGRRRVDAERRLRAFGRRNQVRVALLRAPGIY
                     AADRLPLERLRRGDPVLAADEDVHTNHIHAEDLARIACLALFRAGPGRAYNASDDSGL
                     RMGEYFDAVAERFGLARPPRMARAEIVHHLSPLTLSFMSESRRLDNRRLKRELRLRLR
                     YPTVADGLRAATVPAA"
     gene            902..1915
                     /locus_tag="P5537_15815"
     CDS             902..1915
                     /locus_tag="P5537_15815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-6-deoxy-delta-3,4-glucoseen reductase"
                     /protein_id="HRV79554.1"
                     /translation="MSHRISLQPGNHSFQADDDQTVLEAALAAGLLLPHGCRDGACGA
                     CKGRVLEGEVEHGEHSSGALSEAERGEGLALFCCAKPLGDLVVQARSVTRAGDIQVKR
                     LPCRVQKLERLAEDVMRIELKLPASENFAFRAGQYIDILLADGQRRSFSIANPPHDAG
                     HLELHVRRIDGGRFTGHVFETMLEKEILRFEGPLGSFFLREDSPRPIVMVAGGTGFAP
                     IKGIVEHAIRLGLQRPIALYWGARRRDGLYLDALARSWEAALPGLRYVPVLSDEPWEG
                     RVGLVHEAVLEDFADLSAHEVYACGAPAMIDAARARFCTDRGLPEDAFFADAFTFAQP
                     STR"
     gene            1929..3065
                     /locus_tag="P5537_15820"
     CDS             1929..3065
                     /locus_tag="P5537_15820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDOD domain-containing protein"
                     /protein_id="HRV79555.1"
                     /translation="MSQTTLLTREPVVNKNRAITANRLIAHGPNIAAVVEALSAQAEV
                     WPTHHPVFISLGRLVPTPELMDWAIPANVAIEIPVQTLAHPHTQALMARLRDAGTGMC
                     LTWYQPETALPADHDWRFVLIDARRHAAPTGSPGLSLAWGLPDIGAFRQAVGAGYDGA
                     SGWFFLHGNPPAKSLSPGHAQIVRLLNLVRNNGEIRDIEAVLKQDVALSFKLLRYINS
                     AGFGLMVEIQSFRHAVSILGYDALNKWLSLLLVTASRDPSAPALMQTAIARGRFMEEI
                     GAGFFDAAERDNLFITGAFSLLHTLLGTSIQTLLEEMNLPPRVSEALLYGQGDFAPFL
                     HLAQCCESFDPKALQAAVDQLHLGCEQVNRAQLVGLGFADSLHG"
     gene            3172..5130
                     /locus_tag="P5537_15825"
     CDS             3172..5130
                     /locus_tag="P5537_15825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HRV79556.1"
                     /translation="MFAAHFSAFELQPLPDGASTILRMLAAQTPNWAEIALVAARDPA
                     LSLALLMADPLGAGELQDGLNAALRRRLERLGTDLLRAWLLGLGHVGNAPDETPDAAL
                     LRAECALHLAIETDYPRPDEAYLAGLWYGLPRSAQWIAGRRPTLPALVADCGLPASLA
                     DALELEDVDPIAGGAMHPLLTLLAAARRLAGADWQERIDEAAGLTGLESASVVALRTD
                     VGYILSGHAAYPSPPGFPNAGAACPTLRLADDPYRYAGMLGLLTAAFVDLDAATIRDR
                     LAIACPLFGLHTPPVLLGCGEDGRLRPLLGAAAASPDLLIGELRLRLDDETSCIALGA
                     RSEQPCSHFGDGGPPGRSVADWQVARWLGQPGFHVIPLGGAGDTSVALVATASAQALD
                     SELRWRYAALLGAAARALRSHARQRDAIAEREAALHRRFRDHVRRIAHEASNPLTVLK
                     TRIDMLAQERPGDSTLQDEMSLLNAELDRIDKLLRSAAELPAETAEMRSCRVPELLLD
                     MRTLYGEPLFGSRHIQLELRAARDVPPAAIPASALKQVLLNLLRNASEALQPGQRLVV
                     SVLPLVNVDGHNCLEIRFVDNGPGLPVERAQDPLSPRPSAKGAEHQGLGLAVVREILA
                     QWGGTLLCRTQTGAGTSFQIFVPLEQSA"
     gene            5183..>5911
                     /locus_tag="P5537_15830"
     CDS             5183..>5911
                     /locus_tag="P5537_15830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV79557.1"
                     /translation="MVTPAENGFRPRIDASAGDDADSVRILIVDDDPALRRTFPHVLA
                     RPGRLFDECGSIAEAVGRLEKQRYALILLDYRLPDANGLALLDWLSDHQRDEAVIIIS
                     GEDAIDAAIGALRGGADDYVRKPYHVAQLQRAVDGALHKGTLERANKLMSQRLKDSEK
                     LHRYLVESSPDMIFTLDGSGRFTYINPRVKALLGHDRSALIKRPFTTLVMPEDLDRID
                     TLLSQPSSLPGESFHVELRLRSRRD"
BASE COUNT          839 a         2286 c         1951 g          835 t
ORIGIN      
        1 ctcaggcggc ggggacggtc gcggctcgca gcccgtcggc caccgtcgga tagcgcaagc
       61 gcaggcgcag ttcccgcttc aggcggcggt tgtcgaggcg gcgcgactcg ctcatgaagg
      121 acagcgtgag cggcgacagg tggtggacga tctcggcgcg cgccatgcgc ggcggccgcg
      181 ccaggccgaa gcgctcggcg accgcgtcga agtattcgcc catgcgcagg ccggagtcgt
      241 cgctggcgtt gtaggcccgc ccgggaccgg cgcggaacag cgccaggcag gcgatgcggg
      301 cgaggtcctc ggcgtggatg tggttggtgt gcacgtcctc gtcggcggcg agcaccgggt
      361 cgccgcggcg caggcgctcg agcggcaggc ggtcggcggc gtagatgccg ggcgcgcgca
      421 gcagggccac gcgcacctgg ttgcgccggc cgaaggcgcg caggcggcgc tcggcatcca
      481 cccgccggcg gccgcgcgcg gtctgcgccc ggcacggccg cgtctcgtcc acacggcccc
      541 ccgcacaatc gccgtaaacc cctgtcgtgc ttatgtatac caccccctgt ggtagactcg
      601 accgccctgc cagcgcggcc agcagccgcg ccatgcgcgg gtcgccgtgg cccgtctgcg
      661 gcggcggcgc gaagtgcagc accgcgtcgg cgatgccggc caggcggcgc aggctttggc
      721 gatcgtcgag gtcgcccacc accggcaccg cgccgagtgc gcgcagttcg accgccgcct
      781 cgggctggcg gacgagcgcg aagacgcgaa agcggcgcaa cagccagggc agcgcgcggc
      841 gggcgacatc gccgctgccc acgatcagta ttcttttcat cgtttgatta tctcacgcac
      901 catgagccac cggatttccc tccagcccgg caaccactcc ttccaggccg acgacgacca
      961 gaccgtgctc gaggccgcgc tcgccgccgg cctgctgctg ccgcacggct gccgcgacgg
     1021 tgcctgcggc gcctgcaagg gacgtgtcct cgagggcgag gtcgagcacg gcgagcactc
     1081 ctccggggcg ctgagcgagg ccgagcgcgg cgagggcctg gcgctgttct gctgcgcgaa
     1141 gccgctcggc gacctggtgg tgcaggcgcg cagcgtgacg cgcgcgggcg acatccaggt
     1201 caagaggctg ccctgtcggg tgcagaagct cgagcgcctg gccgaggacg tgatgcggat
     1261 cgagctcaag ctgccggcga gcgagaactt cgccttccgc gccgggcaat acatcgacat
     1321 cctgctcgcc gatggccagc gccgcagctt ctcgatcgcc aacccgcccc acgatgcggg
     1381 tcatctcgag ctgcacgtgc gccgcatcga cggcggccgt tttaccggcc acgtcttcga
     1441 gaccatgctg gagaaggaga tcctgcgctt cgagggtccg ctcggcagct tcttcctgcg
     1501 cgaggactcc ccgcggccga tcgtgatggt ggcgggcggc accggcttcg cgccgatcaa
     1561 gggcatcgtc gagcatgcga tccggctcgg cctgcagcgc ccgatcgcgc tgtactgggg
     1621 cgcgcgccgg cgcgacgggc tctacctcga cgcgctcgcg cgctcatggg aggccgcgct
     1681 gcccggcctg cgctacgtgc cggtgctctc cgacgagccc tgggaaggac gcgtcggcct
     1741 ggtgcatgag gcggtgctcg aggacttcgc cgacctctcc gcccacgagg tctatgcctg
     1801 cggcgccccg gcgatgatcg atgccgcacg cgcccgcttc tgcaccgacc gcggcctgcc
     1861 cgaggacgcc ttcttcgccg acgccttcac cttcgcccag ccctccaccc gctgacccgg
     1921 aacgcccgat gagccagacc accctgctga cccgcgagcc ggtcgtcaac aagaaccgcg
     1981 cgatcaccgc caaccgcctc atcgcccacg gcccaaacat cgccgcggtg gtcgaggcgc
     2041 tctcggcgca ggccgaggtg tggccgaccc atcatccggt attcatcagc ctgggccgcc
     2101 tcgtgcccac gcccgagctg atggactggg cgatccccgc gaacgtcgcg atcgagatcc
     2161 cggtgcagac gctcgcccat ccgcacaccc aggcgctgat ggcgcgcctg cgcgacgccg
     2221 gtaccggcat gtgcctgacc tggtaccagc ccgagacagc cctccccgcg gaccacgact
     2281 ggcgcttcgt gctcatcgat gcgcgccgcc atgccgcccc caccggctcg cccggcctca
     2341 gcctggcgtg gggcctcccg gacatcggcg ccttccgcca ggcggtgggc gccggatacg
     2401 acggcgcctc gggatggttc ttcctgcacg gcaacccgcc ggcgaagagc ctttcgccgg
     2461 ggcacgcgca gatcgtgcgt ctgctcaacc tggtccgcaa caacggcgag atccgcgaca
     2521 tcgaggcggt gctcaagcag gacgtggcgc tctccttcaa gctgctgcgc tacatcaatt
     2581 cggccggctt cggcctgatg gtcgagatcc agtccttccg ccacgcggtc agcatcctcg
     2641 gctacgacgc cctcaacaag tggctgtcgc tgctgctggt cactgccagc cgcgacccca
     2701 gcgcgccggc gctgatgcag accgcgatcg cgcgcggccg cttcatggaa gagatcggcg
     2761 ccggcttctt cgacgccgcc gagcgcgaca atctcttcat caccggcgcc ttctcgctgc
     2821 tgcacaccct gctcggcacc tcgatccaga ccctgctcga ggagatgaac ctgccacccc
     2881 gggtcagcga ggcgctcctc tatggccagg gcgacttcgc ccccttcctg catctggcgc
     2941 agtgctgcga gagcttcgac cccaaggccc tgcaggcggc ggtcgaccag ctccacctcg
     3001 gctgcgaaca ggtcaaccgc gcccagttgg tcggtctcgg cttcgccgac agcctgcacg
     3061 ggtaagtctc atccttctcg ccccccattc ccgtacaccg caacatcggt cacggtgatt
     3121 ggggaggggg tgggctagaa tccgccggcc ctccctccaa ccgtccatcg catgttcgcc
     3181 gcccacttca gcgccttcga gctccagccc ctgcccgacg gcgcgtcgac gatcctgcgc
     3241 atgctcgcgg cgcagacgcc gaactgggcg gagatcgccc tcgtggccgc gcgcgatcca
     3301 gccctgagcc tggccttgct gatggccgac ccgctgggcg cgggcgaact gcaggatggt
     3361 ctcaatgccg ccttgcggcg tcggctggag cgcctcggca ccgacctgct gcgcgcctgg
     3421 ctgctcggtc tcggacacgt cggcaacgcc ccggacgaaa cccccgacgc cgcgctgctg
     3481 cgcgccgaat gtgcgctcca cctcgcgatc gagaccgact acccgcgccc cgacgaggcc
     3541 tacctcgccg ggctgtggta cggcctgccg cgatcggcgc agtggatcgc agggcgccgt
     3601 ccgacgctgc cggccctggt cgccgactgc ggcctgcccg cgagcctcgc cgacgcgctc
     3661 gaactcgagg atgtcgaccc catcgccggc ggcgcgatgc atccgctgct caccctgctc
     3721 gccgccgcac gccggctcgc gggcgccgac tggcaggagc gtatcgacga ggccgccggg
     3781 ctgaccggcc tggagagcgc gagcgtggtc gcgctgcgta ccgacgtcgg ctacatcctt
     3841 tccggccacg cggcgtatcc gtccccaccc ggctttccca acgcgggcgc agcctgcccg
     3901 acgctgcgcc tggcggacga cccctatcgc tacgcgggca tgctcggcct gctcaccgcc
     3961 gccttcgtag acctggacgc ggcgaccatc cgcgaccgcc tggcgatcgc ctgcccactt
     4021 ttcggcctgc acaccccgcc ggtgctgctc ggctgcggtg aggacgggcg gctgcgcccc
     4081 ctgctcggcg ccgccgcggc cagccccgac ctgctgatcg gagagctgcg cctgcgcctg
     4141 gacgacgaga ccagctgcat cgccctcggt gcgcgcagcg aacagccctg ctcgcatttc
     4201 ggcgacggtg gtccgcccgg gcgcagcgtc gcggactggc aggtcgcacg ctggctcggc
     4261 cagccgggct tccacgtcat cccgctcgga ggagcgggcg acaccagcgt ggccctggtc
     4321 gccaccgcct ccgcccaggc gctcgacagc gagctgcgct ggcgctacgc cgccctgctc
     4381 ggcgccgcgg cgcgcgcgct gcgcagccac gcccgccagc gcgatgcgat cgccgaacgc
     4441 gaggcggcgc tgcaccgccg cttccgcgac catgtgcgcc ggatcgccca cgaggcgagc
     4501 aacccgctca ccgtgctcaa gacccgcatc gacatgctcg cccaggagcg ccccggcgac
     4561 agcacgctgc aggacgagat gagcctgctc aacgccgagc tcgaccgcat cgacaagctc
     4621 ctgcgcagcg ccgccgagct acccgccgag accgccgaga tgcgctcctg ccgggtaccg
     4681 gagctgctgc tggacatgcg cacgctgtac ggcgagccgc tcttcggcag ccgccacatc
     4741 cagctcgagc tgcgtgccgc gcgcgacgtg ccgccggccg cgatccccgc ctcggcactc
     4801 aagcaggtcc tgctcaacct gctgcgcaac gcctccgagg cgctccagcc gggccagcgc
     4861 ctggtcgtct cggtgctgcc gctggtcaat gtcgatggcc acaactgcct cgagatccgc
     4921 ttcgtcgaca acggccccgg cctgcccgtc gagcgtgccc aggatccgct cagcccgcgc
     4981 ccgagcgcca agggcgccga gcaccagggg ctggggctcg cggtggtgcg cgagatcctc
     5041 gcgcaatggg gcggcaccct gctgtgccgc acccagaccg gcgccggcac gagcttccag
     5101 atcttcgttc cgctggaaca aagcgcctga gtgttgcatc atgcgcgcga acaaaccctc
     5161 cacctcgcag cctccgggag ccatggtcac tccggccgaa aacgggttca ggcctcggat
     5221 cgacgccagt gccggcgacg acgccgacag cgtgcgcatc ctgatcgtcg atgacgatcc
     5281 ggccctgcgc cgcacctttc cgcacgtgct cgcccgcccc gggcgactct tcgacgaatg
     5341 cggcagcatc gccgaggcgg tcggccgcct ggagaagcag cgctacgcgc tgatcctgct
     5401 cgactaccgc ctgcccgacg ccaacggcct cgccctgctc gactggctgt ccgaccacca
     5461 gcgcgacgag gcggtgatca tcatcagcgg cgaggacgcg atcgacgcgg ccatcggcgc
     5521 actgcgcggc ggcgccgacg actacgtgcg caagccctac cacgtcgcgc agttgcagcg
     5581 tgcggtcgat ggcgccctgc acaagggcac gctcgaacgc gccaacaagc tgatgagcca
     5641 gcgcctgaag gattcggaga aactccaccg ctatctggtg gagagctccc ccgacatgat
     5701 cttcacgctc gacggcagcg gccgcttcac ctacatcaac ccgcgcgtca aggccctgct
     5761 cggccacgac cgcagcgcgc tcatcaagcg ccccttcacc accctggtga tgcccgagga
     5821 cctcgaccgc atcgacaccc tgctcagcca gccgagcagc ctgcccggcg agagctttca
     5881 cgtcgagctg cgcctgcgct cgcggcgcga c
//
LOCUS       DAOTIN010000170         5764 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_16519_length_5764_cov_8.055001, whole genome shotgun sequence.
ACCESSION   DAOTIN010000170 DAOTIN010000000
VERSION     DAOTIN010000170.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 5764)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5764)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5764
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_16519_length_5764_cov_8.055001"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..>1159)
                     /locus_tag="P5537_15835"
     CDS             complement(<1..>1159)
                     /locus_tag="P5537_15835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014237568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HRV79558.1"
                     /translation="VPTNIYAGIAKYPLLAIPMFILAGMIFERSGVAIRLVRFVTAMV
                     GEWTGSLAVVAVLVSMLLGGISGSGPADAAAVAAVMLPSMIARGYPKGFSAGLIAASG
                     STAIVIPPSVAFIVYSVMVPAATVPALFAAGLFPGMVAALCLLVPAIVISRKYGFGRD
                     YKAERPPLGKSFIDAIWGLLAPVIILGGLRTGIFTPTEAAVVAVAYGIFVGMVVYRSI
                     SFRGLFRVLVEAGELSAVVLMIIGIASVFAWAGNTLGIFDAAAKALVGLHSSEWLMLL
                     SINLLLLAAGMFLDAISIFLILLPLLVPIAIAMGWDLVWFGVMMTINLAIGQFTPPMA
                     ISLMITSRIAGIGMEETFKWVVWLVLAMGAGLALMIVFPQLALWLPGRLGYL"
     assembly_gap    1160..1259
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<1260..1712)
                     /locus_tag="P5537_15840"
     CDS             complement(<1260..1712)
                     /locus_tag="P5537_15840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004265732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015740 - C4-dicarboxylate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HRV79559.1"
                     /translation="MTTESPLHDAETPAPYTIEQILSGIVMGLIVLITFGNVLARYFT
                     SQSFAATEEFSIALLIVLSFLGSSAAFAFDRHIRVDFFVRKLPPGLHAFIDWLSFAVT
                     ASLFAFIAFYAGKLTWDQYRFEETSPALGVPQWWYTVWMPVLAVALVLR"
     gene            complement(1792..2823)
                     /locus_tag="P5537_15845"
     CDS             complement(1792..2823)
                     /locus_tag="P5537_15845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DctP family TRAP transporter solute-binding
                     subunit"
                     /protein_id="HRV79560.1"
                     /translation="MQKRRFTALIAGLAASAALGFSMPATAQQYKDEYKLSTVLGEAF
                     PWGWGAKRWADLVAEKTEGRIKIKVYPGTSLVSGDQTKEFTALRQGIIDMAVGSTINW
                     SPQVKELNLFALPFLMPDHKAIDALTQGRVGTKMFEILADRDVVPLAWGENGFREVSN
                     SKKPIRTPEDLKGMKMRVVGSPLFLATFNALGANPTQMSWADAQPAMATGAVDGQENP
                     LAVFNAAKLHTVGQKNLTLWGYVADPLIFVVNKNVWNSWSEADRKAVSEAAQQAAKEE
                     IARARAGISAGDDALLKEIEANGVAVVRLSDAERSAFRTATAGVYKEWAEKIGGDLVK
                     QAEEDIAKR"
     gene            complement(2975..3925)
                     /locus_tag="P5537_15850"
     CDS             complement(2975..3925)
                     /locus_tag="P5537_15850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004265730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HRV79561.1"
                     /translation="MGAQGLIAAFTAGAATLAGGRALVHWGIRRGLAAPRVPHHTEPG
                     ALGLAFETLRIDTENGKSLHAWFIPGPARAAVADADAATAAAREEAENPPAAAPAVLV
                     MHGWGGNAALMLPLARPLHEAGYATLFVDARCHGASDDDSFASLPRFAEDTEHAFAWL
                     SAREGVDPARIALLGHSVGAGAVLFAASRTPQVAAVVSVAAFSHPAAMMRRWLATKRI
                     PEKPIGRYILDYVQKTIGHRFDDIAPVTTIARIRRPVLLVHGADDEVVPIDEAMQIYA
                     MRGDTPVELMTLTGDHESFADLEHHMGRLVGFLDRSIAPR"
     gene            complement(3939..4286)
                     /locus_tag="P5537_15855"
     CDS             complement(3939..4286)
                     /locus_tag="P5537_15855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004265728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HRV79562.1"
                     /translation="MNTVVLEVRSLAETLADAARAMKTGRGDAQARIAFASPELLWKV
                     LSAKRWELLKALCAAGPVSIREAARRVGRDVKTVHGDVSALLDAGVLSRTDDGRIEFP
                     FDAVKVEFLLQAA"
     gene            complement(4311..4847)
                     /locus_tag="P5537_15860"
     CDS             complement(4311..4847)
                     /locus_tag="P5537_15860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HRV79563.1"
                     /translation="MTPATDETPKPPRWRRWAVEIGIFVAVFFAIQAWMARDVPAGPA
                     PDFATVAADGRALSLAEWRSAHLGQAVGVYFWAEWCPICTAQQGTIEGVQADYPVLTV
                     AMQSGGAAAVKSVLAERGLDWTTAIDADGRIAQTYGLRGVPAFVIVDPAGQIRSVSLG
                     YTTGWGLRARLWWAGVDI"
     gene            complement(4844..>5764)
                     /locus_tag="P5537_15865"
     CDS             complement(4844..>5764)
                     /locus_tag="P5537_15865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004360228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HRV79564.1"
                     /translation="WISELTYLRGHRGVTHSLILLPLWGLLIAWLLARFWQRGGRVAA
                     GWRSFYPVVCAAIFVHILGDLITQFGTMILAPFSDQRFGWGTTFIIDLPFTGIIVAGL
                     FASALWRSSRLPAATALVLLAGWVGVQATGRAEAIDAARAYAAANGIAAVEVDAAPRP
                     ASPFNWTAIVFDGERYHYAHINTRRSEPLVATEDDNFIRRFSAPYLPVAMAQWEVRER
                     FGNGSTRALAEQVWNAEDFAFYRWFAMFPVLDHAGEGADGERCASFKDLRFLTPGRDR
                     QPFIYGLCNVADGWRLFEREAGGLRWIDPR"
BASE COUNT          958 a         1956 c         1956 g          794 t
ORIGIN      
        1 acaggtagcc gagcctcccc ggcagccaca gcgcgagctg cgggaacacg atcatcagcg
       61 ccagcccggc gcccatcgcc agcaccagcc agacgaccca cttgaaggtc tcctccatgc
      121 cgatgccggc gatgcgcgag gtgatcatca gcgagatcgc catcggcggc gtgaactggc
      181 cgatggcgag gttgatcgtc atcatcacgc cgaaccacac caggtcccag cccatcgcga
      241 tcgcgatcgg caccagcagt ggcagcagga tcaggaagat cgagatcgcg tcgaggaaca
      301 tgcccgcggc gagcagcagc aggttgatcg acagcagcat cagccactcg ctcgagtgca
      361 gcccgaccag cgccttcgcc gcggcatcga agatccccag cgtgttgccc gcccaggcga
      421 acaccgaggc gatgccgatg atcatcagca ccaccgccga cagttcgccg gcctcgacca
      481 gcacgcggaa caggcctcgg aagctgatgc tgcgatacac caccatgccg acgaagatgc
      541 cgtaggccac cgccaccacc gccgcctcgg tcggcgtgaa gatgccggtg cgcaggccgc
      601 cgaggatgat caccggcgcc agcagtcccc agatcgcatc gatgaagctc ttgcccagcg
      661 gcgggcgttc cgccttgtag tcgcggccga agccatattt gcggctgatc acgatcgccg
      721 gcacgagcag gcacagcgcg gccaccatgc cggggaacag tcccgccgcg aacagcgccg
      781 gcacggtcgc cgccggcacc atcacgctgt agacgatgaa ggccaccgag ggcgggatga
      841 cgatcgcagt cgagcccgag gcggcgatca ggccggccga gaagcccttc ggatagccgc
      901 gcgcgatcat cgacggcaac atcaccgccg ccaccgcggc cgcgtccgcc gggccggagc
      961 cggagatgcc gccgagcagc atcgacacca gcaccgccac caccgcgagc gagccggtcc
     1021 attcgccgac catcgcggtg acgaagcgca ccaggcggat cgccaccccc gagcgctcga
     1081 agatcatgcc ggcgaggatg aacatcggga tcgccagcag cgggtacttg gcgatcccgg
     1141 cgtagatgtt ggtcggcacn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnng
     1261 cgcagcacca gcgccaccgc cagcaccggc atccacaccg tgtaccacca ctgcggcacg
     1321 ccgagcgcgg gcgaggtctc ctcgaagcga tactgatccc aggtgagctt gccggcgtag
     1381 aaggcgatga aggcgaacag gctggcggtg accgcgaacg acagccagtc aatgaacgcg
     1441 tgcaggcccg gcggcagctt gcgcacgaag aaatctacgc ggatgtgccg gtcgaaggcg
     1501 aaggccgccg acgagccgag gaaggacagc acgatcagca gcgcgatcga gaactcctcg
     1561 gtcgcggcga aggactgcga ggtgaagtag cgcgccagca cgttgccgaa ggtgatcagc
     1621 acgatcaggc ccatgacgat gccggagagg atctgttcga tcgtgtaagg ggcgggtgtt
     1681 tcagcgtcgt gcaggggcga ttcggtcgtc atcggttcgg tgtactttca acggaaaaag
     1741 gccgggcagc ccatttcggg tactgcccgg ccagcgtgcc gcgggtgcgg atcaacgctt
     1801 ggcgatgtct tcctcggcct gcttcaccag gtcgccaccg atcttctcgg cccattcctt
     1861 gtacacgccg gcagtggcgg tgcggaaggc gctgcgctcg gcgtcggaca ggcgcaccac
     1921 ggccacgccg ttggcttcga tctccttgag cagcgcgtcg tcgcctgccg agatgccggc
     1981 gcgggcgcgg gcgatctctt ccttcgcggc ctgctgcgcg gcctcggaca ccgccttgcg
     2041 gtcggcctcg gaccacgagt tccacacgtt cttgttgacc acgaagatca gcgggtcggc
     2101 gacgtagccc cacagcgtca ggttcttctg ccccacggtg tgcagcttgg cggcgttgaa
     2161 caccgcgagc gggttctcct ggccgtcgac cgcgccggtc gccatcgccg gctgggcgtc
     2221 ggcccagctc atctgcgtgg ggttggcgcc gagcgcgttg aaggtggcga ggaagagcgg
     2281 cgagcccacc acgcgcatct tcatgccctt gagatcttcc ggcgtgcgga tcggcttctt
     2341 cgagttggag acctcgcgga agccgttctc gccccaggcc agcggcacca cgtcacggtc
     2401 ggcgaggatc tcgaacatct tcgtgccgac gcggccctgg gtgagggcgt cgatcgcctt
     2461 gtggtccggc atcaggaagg gcagcgcgaa gaggttgagc tccttgacct gcggcgacca
     2521 gttgatggtc gagcccaccg ccatgtcgat gatgccctgg cgcagcgcgg tgaattcctt
     2581 ggtctggtcg cccgacacca gcgaggtgcc cggatagacc ttgatcttga tgcggccttc
     2641 ggtcttctcg gcgaccagat cggcccagcg cttggcgccc catccccagg ggaaggcttc
     2701 gccgagcacg gtggagagct tgtactcgtc cttgtactgc tgggccgtcg ccggcatcga
     2761 gaagccgagc gcggcggagg cggcgaggcc ggcgatgagg gcggtgaagc ggcgtttctg
     2821 catgagacgt ctccgttttc gtggttttga gatgagacgc gcggcggcgg acgcagcgca
     2881 aggggagggc cgattctaca aaccggggcg ccccgcggcc agcagggatt cccaccgcct
     2941 gaagatcgag ggggtcagac cccattgatt tcgttcagcg cggcgcgatg ctgcggtcga
     3001 ggaacccgac cagccggccc atgtggtgct cgaggtcggc aaaggattcg tggtcgcccg
     3061 tcagcgtcat cagctcgacc ggggtgtcgc cgcgcatggc gtagatctgc atggcctcgt
     3121 cgatcggcac cacctcgtcg tcggcgccat gcaccagcag caccggacgg cggatgcgcg
     3181 cgatcgtggt caccggcgcg atgtcgtcga agcggtggcc gatggtcttc tgcacgtagt
     3241 cgaggatgta gcgcccgatc ggcttctcgg ggatgcgctt ggtcgccagc cagcgtcgca
     3301 tcatcgccgc cgggtgcgag aacgccgcca cgctgaccac cgccgccacc tgcggcgtgc
     3361 gcgaggccgc gaacagcacc gcgccggcgc cgaccgaatg gccgagcagc gcgatgcggg
     3421 cggggtcgac gccctcgcgc gcggagagcc acgcgaaggc gtgctcggtg tcctcggcaa
     3481 agcgcggcag cgaggcgaag ctgtcgtcgt cgctcgcgcc gtggcagcgc gcgtcgacga
     3541 acagcgtcgc gtagccggcc tcgtgaagcg gccgggcgag cggcagcatc agcgccgcat
     3601 tgccacccca gccgtgcatc accagcaccg ccggcgcggc cgcgggcggg ttctccgctt
     3661 cctctcgagc cgcggcggtc gccgcgtccg catcggcaac ggcggcgcga gccggcccgg
     3721 gaatgaacca cgcatgcagc gacttgccgt tctcggtgtc gatgcgcagc gtctcgaacg
     3781 ccaacccgag cgcgccaggc tccgtgtgat gcggcacacg cggcgccgcc aggcccctgc
     3841 ggatccccca atgcaccagc gcccgcccac cggcgagcgt ggctgcaccg gcggtgaagg
     3901 cggcgatcag tccctgtgcg cccattcgaa agtgctcctc aggccgcctg cagcagaaac
     3961 tcgaccttca ctgcatcgaa cggaaactcg atccgtccgt cgtcggtcct ggacagcacg
     4021 ccggcatcga gcaaggcgct gacgtcgcca tgcaccgtct tgacgtcgcg cccaacccgg
     4081 cgtgccgcct cccggatcga caccgggccc gccgcacaca gcgccttcag caactcccag
     4141 cgcttggcgc tcagtacctt ccaaagcagt tctggcgagg caaaggcgat ccgggcctgg
     4201 gcgtcgccgc gcccggtttt catcgcgcgc gcggcgtcgg ccaaggtctc ggccaggctg
     4261 cgtacttcaa gaacgaccgt gttcatgatt ccacctcgca atgtccgcgc tcagatgtcg
     4321 acacccgccc accacaagcg tgcgcgcagc ccccagccgg tggtgtagcc gagcgacacc
     4381 gagcggatct ggcctgccgg gtcgacgatg acgaaggccg gcacgccgcg cagcccgtag
     4441 gtctgggcga tgcgaccgtc ggcgtcgatg gcggtggtcc agtctagacc gcgttcggcg
     4501 agcaccgact tcacggcggc cgcgccgccc gactgcatgg cgacggtgag caccggatag
     4561 tcggcctgca cgccctcgat cgtaccctgc tgcgcggtgc agatcgggca ccactcggcc
     4621 cagaaataca cgcccaccgc ctggcccaga tgggcggaac gccactcggc gaggctgagt
     4681 gcacggccgt cggcggcgac ggtggcgaaa tccggggcgg ggccggcggg cacgtcgcgc
     4741 gccatccagg cctggatggc gaagaagacg gcgacgaaga taccgatctc gaccgcccag
     4801 cgccgccagc gcgggggctt gggagtttcg tccgtcgccg gcgtcatcgc ggatcgatcc
     4861 agcgcagccc accggcctcg cgttcgaaca ggcgccagcc gtcggcgacg ttgcacaggc
     4921 cgtagatgaa gggttggcgg tcgcgccccg gggtgaggaa gcgcagatcc ttgaagctgg
     4981 cgcaacgctc gccatccgcc ccctcgcccg catggtcgag caccgggaac atcgcgaacc
     5041 agcggtagaa ggcgaagtcc tcggcgttcc acacctgctc ggcgagcgcg cgcgtgctgc
     5101 cgttgccgaa gcgctcgcgc acctcccact gcgccatcgc caccggcagg tagggcgcgg
     5161 agaagcggcg gatgaagttg tcgtcctctg tggccaccag cggctcgctg cgccgggtgt
     5221 tgatgtgggc gtagtggtag cgctcgccgt cgaacacgat cgcggtccag ttgaagggcg
     5281 aggccggacg cggcgcggcg tcgacctcga ccgccgcgat gccgttcgcg gcggcgtagg
     5341 cgcgcgcggc gtcgatggcc tcggcgcggc ccgtcgcctg cacgcccacc cagccggcga
     5401 gcagcaccag cgcggtcgcc gccggcaggc ggctgctgcg ccacagcgcg ctggcgaaca
     5461 ggccggccac gatgatgccg gtgaagggca ggtcgatgat gaaggtggtg ccccagccga
     5521 agcgctggtc cgagaacggc gccaggatca tggtgccgaa ctgggtgatg aggtcgccga
     5581 ggatgtgcac gaagatcgcc gcgcacacca ccgggtagaa gctgcgccag cccgcggcca
     5641 cccgcccgcc gcgctgccag aagcgcgcca gcagccaggc gatcagcagg ccccacagcg
     5701 gcaaaaggat cagcgagtgg gtgacgccgc ggtggccgcg caggtaggtg agctcggaga
     5761 tcca
//
LOCUS       DAOTIN010000171         5741 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_16613_length_5741_cov_8.582483, whole genome shotgun sequence.
ACCESSION   DAOTIN010000171 DAOTIN010000000
VERSION     DAOTIN010000171.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 5741)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5741)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5741
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_16613_length_5741_cov_8.582483"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(133..417)
                     /locus_tag="P5537_15870"
     CDS             complement(133..417)
                     /locus_tag="P5537_15870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79565.1"
                     /translation="MADFPLPILFIMVVFFAMWLILRKYHRMEQRKRALPELNAYLYA
                     NNQTEPRCSACESTEFKDEGLTHGKDERRIVSCAKCDTLLYRIVPPDRDE"
     gene            complement(483..1823)
                     /locus_tag="P5537_15875"
     CDS             complement(483..1823)
                     /locus_tag="P5537_15875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004383221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HRV79566.1"
                     /translation="MAALQLTPAEWLLAGLLLAVLVLQAWQLLRGGGAERRLRERLAD
                     DLGDLMEQRLAARHRELLIDLHDGLSRQTDRIGEHARADRELLQRGLTSASLQLSRGM
                     QALTQSVDGRLDTLSGQVNQRLDEGFRKTNETFASVMARLATIDEAQKKIDGLTTNVV
                     SLQELLGDKRARGAFGEVQLENLVRNMLPPEAFAFQQVLPNGTRVDCLLTLPAPTGNV
                     AVDAKFPLENYHRMFDDALAELDRRAAQQAFRADVKRHVDAISAKYILPGSTADGAVM
                     FLPAEAVFAELHAYHPEVVAYAQHKRVWIVSPTTLMAVLNTARAVMKDVETRKQIHVI
                     QDALGKLAKDFQRFDERMAALARHIEQASRDVQEVHTSSRKISAHFRRIESVQLDEED
                     EGGEGNEEGGPGKFTVAGNPRGPATVAGRRGGSPARFDAGQGLPAASSVSSDPF"
     gene            complement(1828..4326)
                     /locus_tag="P5537_15880"
     CDS             complement(1828..4326)
                     /locus_tag="P5537_15880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HRV79567.1"
                     /translation="MMRNLRLALRMMLRDLRAGELHLLGLAIVIAVASLTSVGFLADR
                     VGRALDREANQLLGGDLLLRADKPWPDRFIDEARSRGLQTAKTVLFTSMASTAEGAAL
                     GGVKVVEDGYPLRGTIRLAPGPNQPDAPAGRAPASGEVWLDERLFAELGVKAGDKVGL
                     GELEFRVGAMVSFEADRGANFFSLLPRAIFNLKDLDATGLIAEGSRATWRLHVAGTPQ
                     AVETYEKWARANLGRGQRVETVDNARPEVRAALDQAQRFLRLAALLAVILAAVAVGLS
                     ARRFMARHLDGCAVMRVLGARQAQVLGIVVGEFLLFGLAAALLGTALGWTVQWGLAGG
                     LRELLATELPAPSPLPLAHGLVVGMALLAGFVLPQLLRLGKVSTLRVLRREFEFAEPV
                     SGAAWGLGLAALLGLIFWIAADARLGAMVAAGFAVALGVFALAAWGVLRLAGRLKGQG
                     SLRGGGWRYGIAALGRRMGSSVIQAAALGLGMTALLLLTLVRADLLDNWRRMAPPDAP
                     NRFVINIQPDQRAGIAALFAAEGLPVPPIQPMIRGRMVAIDGKPVDPSAYEDERTRRL
                     AEREFNLSYGAALPPGNVVETGRWHAAAAQAQFSVEAGLAKTFGLAVGDRVTFEIGGR
                     RVEAPITSVRKLDWDSMRVNFFFIASPGVLEDFPATLITSFHLPPARHDFTTRLVGEF
                     PNLTVIDTAAVIAQVQSMTDKLIVIVQFVFGFAVLAGLVVLYAALQSTHDERDYELAM
                     LRTLGARNRQVRQALFAEFLVLGGVAGVLAGVGASAIGWVLAEQVFRMPYVPALAPVL
                     VGVVLGAVGVVAGGWLGTRTLLSRPPLASLRALG"
     gene            complement(4337..5509)
                     /locus_tag="P5537_15885"
     CDS             complement(4337..5509)
                     /locus_tag="P5537_15885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20 aminoacylase family protein"
                     /protein_id="HRV79568.1"
                     /translation="MSLIESVRPLQGKLTAIRRDIHAHPELAFEEHRTAELVARHLEA
                     LGIETHRGVGGTGVVGVVRGRRGLRAIGLRADMDALPITERNEFAHKSTVHGCMHACG
                     HDGHTTMLLGAAEALAARRDFDGTVYLIFQPAEEGEGGAPAMIADGLFERFPMEAVFG
                     MHNWPGMEAGTFAIHSGPVMASADRFDIRFTGVGAHAAMPHLGVDPVVAGAAFVQAAQ
                     TLVSRVLDPIDAGVVSVTQFHAGEAYNVIPDRAELCGTVRTFSAEVRDRLERGLRQVA
                     EGIAQSHGVEVDFQFRRGYPPTINTAAEAALCAEAARAVAGPERVFTDRRPSMGAEDF
                     AYFLLEKPGAYVWVGNGPGEGGCMLHNPNYDFNDEVLPAGVAYWCALVQRLLGAAR"
BASE COUNT          831 a         2036 c         2095 g          779 t
ORIGIN      
        1 tgtaggagcg ccggcaggcg cgaaagcggc gtcgatgacc tgtgacaacg tcgcccctgc
       61 accgccacat tcgcggctgc cgccgctcct acaggggcgg cagcgtggca ggtgcggcgg
      121 gggtgtggcg gctcattcgt cgcggtccgg cgggacgatg cggtacagga gggtgtcgca
      181 cttggcgcac gacacgatgc ggcgctcgtc cttgccgtgg gtgaggccct cgtccttgaa
      241 ctcggtcgac tcgcaggcgg agcagcgcgg ctcggtctgg ttgttggcgt agaggtaggc
      301 gttgagctcg gggagcgcac gcttgcgctg ctccatgcgg tgatatttcc gcaggatcag
      361 ccacatggcg aagaagacca ccatgatgaa aaggatcggc aggggaaagt cggccatcgg
      421 tgcgggggtc ccggggttgt ggatcggagg gtgggggaag gcggaacgac gtcgtccgcg
      481 cgctagaacg ggtccgacga tacggaggac gccgccggca atccctgtcc cgcatcaaat
      541 cgggcaggcg atcctccgcg cctccctgcg accgtggcag gcccgcgggg attccccgcc
      601 accgtaaatt tccccgggcc gccctcctcg ttcccctcgc ccccctcatc ctcctcatcg
      661 agctgcaccg actcgatgcg gcggaagtgc gcgctgatct tgcggctgga cgtatgcacc
      721 tcctgcacgt cgcggctggc ctgctcgatg tggcgggcga gcgcggccat gcgctcgtcg
      781 aagcgctgga agtccttcgc gagcttgccg agggcgtcct ggatgacgtg gatctgcttg
      841 cgcgtctcga cgtccttcat caccgcacgt gcggtgttga gcaccgccat cagcgtggtc
      901 ggcgacacga tccacacgcg cttgtgctgc gcgtaggcga cgacctcggg gtggtaggcg
      961 tgcagctcgg cgaacaccgc ctcggcgggc aggaacatca ccgcgccgtc ggcggtgctg
     1021 ccgggcagga tgtacttggc ggagatcgca tcgacatggc gcttgacgtc ggcgcgaaag
     1081 gcctgctgtg cggcgcggcg gtcgagctcg gcgagcgcgt cgtcgaacat gcggtggtag
     1141 ttctcgagcg ggaacttggc atcgacggcg acgttgccgg tgggcgccgg cagggtgagc
     1201 aggcagtcga cccgggtgcc gttgggcagc acctgctgga aggcgaaggc ctcgggcggc
     1261 agcatgttgc gcaccaggtt ctcgagctgg acctcgccga aggcgccgcg cgcgcgcttg
     1321 tcgccgagca gctcctgcag gctcacgacg ttggtggtga ggccgtcgat cttcttctgc
     1381 gcctcgtcga tcgtcgccag gcgcgccatc acgctggcga aggtctcgtt ggtcttgcgg
     1441 aagccctcgt cgaggcgctg gttgacctgg ccggagagcg tgtccagccg cccgtccacg
     1501 ctctgggtga gcgcctgcat gccgcgcgac agctgcagcg aggcggacgt gagcccgcgc
     1561 tgcagcagct cgcggtctgc gcgcgcgtgc tcgccgatgc ggtcggtctg gcggctgagg
     1621 ccgtcgtgga ggtcgatcag cagctcgcga tggcgcgcgg cgaggcgctg ctccatcagg
     1681 tcgccgaggt cgtcggccag gcgctcgcgc aggcggcgct cggcgccgcc gccgcgcagc
     1741 agctgccagg cctgcaggac cagcaccgcg agcagcagac cggcgagcag ccactcggcc
     1801 ggcgtcagtt gcaaggctgc catgccttca gcccagcgca cgcaggctgg ccagcggtgg
     1861 ccggctcagc agggtacgcg tgcccagcca gccccctgcg accaccccca ccgcgcccaa
     1921 cacaacccca accagcaccg gcgccagcgc cggcacgtaa ggcatgcgga agacctgctc
     1981 ggccagcacc cagccgatcg cgctcgcgcc cacgcccgcg agcacgccgg cgaccccgcc
     2041 cagcacgagg aattcggcga acaaggcctg gcgcacctgg cggttgcgcg cgcccagggt
     2101 gcgcagcatg gcgagctcgt agtcgcgctc gtcatgcgtc gactgcagcg cggcatacag
     2161 cacgaccagg ccggcgagca ccgcgaagcc gaacacgaac tgcacgatca cgatcagctt
     2221 gtcggtcatc gactgcacct gcgcgatcac cgcggcggtg tcgatcacgg tgaggttggg
     2281 gaactcgccg accagcctgg tggtgaagtc gtggcgcgca ggcggcaggt ggaagctggt
     2341 gatcagcgtc gcggggaaat cctccagcac gccgggcgag gcgatgaaga agaagttcac
     2401 ccgcatcgag tcccagtcga gcttgcgcac gctggtgatc ggcgcctcga cgcggcggcc
     2461 gccgatctcg aacgtcacac ggtcgcccac cgcgagcccg aaggtcttcg ccagccccgc
     2521 ctcgacggag aactgcgcct gcgccgcagc cgcgtgccag cgcccggtct cgacgacgtt
     2581 gcccggcggc agcgcggcgc cgtaggacag gttgaactcg cgctcggcca ggcgccgcgt
     2641 gcgctcgtcc tcgtacgccg acgggtcgac cggcttgccg tcgatcgcca ccatgcggcc
     2701 gcggatcatc ggctggatgg gcggcaccgg caggccctcg gccgcgaaca gcgcggcgat
     2761 gcccgcgcgc tggtcgggct ggatgttgat cacgaagcgg ttgggcgcgt cgggcggcgc
     2821 catccgccgc cagttgtcga ggaggtcggc gcgcaccagg gtgagcagca gcagcgcggt
     2881 catgcccagg ccgagcgcgg cggcctggat cacgctgctg cccatgcggc ggccgagcgc
     2941 ggcgatgccg tagcgccagc cgccaccgcg caggctgccc tggcccttga gccgcccggc
     3001 gagcctgagc acgccccagg cggcgagcgc gaacacgccg agcgccaccg caaagcccgc
     3061 cgccaccatg gcgccgaggc gcgcgtcggc ggcgatccag aagatcaggc cgagcagcgc
     3121 cgccagcccg agcccccagg ccgcgcccga gaccggctcg gcaaactcga actcgcgccg
     3181 cagcacgcgc agggtgctga ccttgcccag gcgcagcagc tgcggcagca cgaagccggc
     3241 gagcagcgcc atgccgacca ccaggccatg ggcgagcggc agcggcgagg gcgcggggag
     3301 ctcggtggcg agcagctcgc gcaggccgcc cgccagcccc cactgcaccg tccagccgag
     3361 cgcggtcccg agcagcgcgg cagccagccc gaagagcagg aactcgccga ccacgatgcc
     3421 cagcacctgc gcctgacggg ctccaagcac gcgcatcacc gcgcagccgt cgaggtggcg
     3481 cgccatgaag cggcgcgccg acaggcccac cgccaccgcg gcgaggatca ccgcgagcag
     3541 tgcggccagg cgcaggaagc gctgtgcctg gtcgagcgcg gcgcgcacct cggggcgggc
     3601 gttatccacc gtctcgacac gctggccgcg gcccaggttg gcgcgcgccc atttctcgta
     3661 ggtctccacc gcctgcggcg ttccggccac gtgcagccgc caggtggcgc ggctgccctc
     3721 ggcgatcagg ccggtggcgt cgaggtcctt caggttgaag atcgcgcgcg gcagcaggct
     3781 gaagaagttg gcgccgcggt cggcctcgaa gctgaccatg gcgccgacgc ggaactcgag
     3841 ctcgcccagg cccaccttgt cgccggcctt cacgcccagc tcggcgaaca ggcgctcgtc
     3901 cagccacacc tcgcccgacg caggcgcacg gcccgcggga gcgtcgggct ggttggggcc
     3961 cggcgccaga cggatggtgc cgcgcagcgg gtagccgtcc tccaccacct tgacgccacc
     4021 gagcgccgcg ccctcggcgg tgctcgccat gctggtgaac agcaccgtct tcgcggtctg
     4081 caggccgcgg ctgcgcgcct cgtcgatgaa gcggtcgggc cacggcttgt cggcgcgcag
     4141 cagcaggtcg ccgccgagca gctggttggc ctcgcggtcg agcgcgcgcc cgacgcggtc
     4201 ggcgagaaag cccacgctgg tcaggctggc caccgcgatc acgatcgcca gcccgagcag
     4261 gtgcagctcg cccgcacgca ggtcgcgcag catcatgcgc agggcgagac gcaggtttcg
     4321 catcatgccg ccgacctcag cgcgccgcgc ccagcaggcg ctgcaccagc gcgcaccagt
     4381 aggccacgcc cgccggcagc acctcgtcgt tgaagtcgta gttggggttg tgcagcatgc
     4441 agccgccctc acccgggccg ttgccgaccc acacataggc gcccggcttc tcgaggagga
     4501 aataggcgaa gtcctccgcg cccatgctcg ggcggcggtc ggtgaacacg cgctccggcc
     4561 ccgccaccgc gcgcgcggcc tcggcgcaca gcgcggcttc cgcggcggtg ttgatggtcg
     4621 gggggtagcc gcgacggaac tggaagtcga cctcgacgcc gtggctctgc gcgatgccct
     4681 cggccacctg acgcaggccg cgctcgagac ggtcgcgcac ctcggcggag aaggtgcgca
     4741 ccgtgccgca cagctcggcg cggtcgggga tcacgttgta ggcctcgccg gcgtggaact
     4801 gcgtcaccga caccacgccg gcgtcgatcg ggtcgagcac gcggctgacc agagtctgcg
     4861 ccgcctgcac gaaggcggcg cccgccacta ccgggtccac gcccaggtgc ggcatcgcgg
     4921 catgcgcgcc gacgccggtg aagcggatgt cgaagcggtc ggcgctcgcc atcaccggcc
     4981 cgctgtggat ggcgaaggtc cccgcctcca tgcctggcca gttgtgcatg ccgaacaccg
     5041 cctccatcgg gaagcgctcg aagaggccgt cggcgatcat cgccggcgcg ccgccctcgc
     5101 cctcctcggc gggctggaag atcaggtaga ccgtgccgtc gaagtcgcgc cgcgcggcga
     5161 gcgcctcggc cgcgccgagc agcatggtgg tgtggccgtc gtggccgcag gcgtgcatgc
     5221 agccgtgcac ggtcgatttg tgcgcgaact cgttgcgctc ggtgatcggc agcgcgtcca
     5281 tgtcggcgcg caggccgatc gcgcgcaggc cgcggcggcc gcgcaccacg ccgaccacgc
     5341 cggtgccgcc gacgccgcgg tgggtctcga tgccgagcgc ctcaaggtgg cgcgcgacca
     5401 gctcggcggt gcggtgctcc tcgaaggcga gctcggggtg ggcgtggatg tcgcggcgga
     5461 tcgcggtcag cttgccctgc agggggcgga cgctttcgat gaggctcatg gctgcaccgt
     5521 gttgttgtgg tttgttgcgg gtgtccgagt gtagtacagg cggagggagg gtgacccttc
     5581 ggccgtggaa gcaggcgtgc cgaaacgcgg ggcgattgct gtacggccct tttcgcggct
     5641 gccgccgctc ctacagaaca ccatcccggc tccgtggttc gcaggtgcgc ccgaaggcgc
     5701 gaaaacatac cgtcccggct cggcggactg ccggggctcc g
//
LOCUS       DAOTIN010000172         5691 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_16803_length_5691_cov_8.492903, whole genome shotgun sequence.
ACCESSION   DAOTIN010000172 DAOTIN010000000
VERSION     DAOTIN010000172.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 5691)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5691)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5691
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_16803_length_5691_cov_8.492903"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            364..1059
                     /locus_tag="P5537_15890"
     CDS             364..1059
                     /locus_tag="P5537_15890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CerR family C-terminal domain-containing
                     protein"
                     /protein_id="HRV79569.1"
                     /translation="MPDLAEHARTVRGRGRPRGPDANYRARLLDAALDAFGAQGFEAA
                     GLRAIAADAGCDVSMVAHYFGSKAELWAAVVERLEAQVRADLAALDMLAPAAGPIERR
                     VVAAVEAMFVHAARQPQAMRFVMRQMTDPGERLDELVARVVEPVHAVFLPVWQEAIDA
                     GLFHMRSALALQAFVFGAISYAVAAAPVLARMSGGEIDLARLQREFGDGLFARFARGR
                     ADAEGDEAGEGTR"
     gene            1056..2213
                     /locus_tag="P5537_15895"
     CDS             1056..2213
                     /locus_tag="P5537_15895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV79570.1"
                     /translation="MSEALLREPRPGEATIDGEGAGAVLRLRGDWTLAHHAALRRQAE
                     ALRGRLEAATRVEAGELGTLDTAGARLLHGLLGGERVAALLAGDGGLSRERRALLKAV
                     AEAIEGREDKPAEPEGSAIGDVLAHIGHTMGVFWRHVTGLTGFVGLILESALRVSVQP
                     RRWRMTALVANLERTGLDAVPIIALLTFLIGAVVAFLGATVLANFGASIFTVDLVTYS
                     FLREFGVLLTAIIVAGRTASSFTAQIGSMRANEEIDAIRVLGLDPVELLVLPRVYALM
                     LALPMLTFIAMLSGIVGGMLVSALTLDISPVLFLSRIEDNVGLIHFWVGMAKAPIFAF
                     LIAVIGCLEGFRVQGSAQSVGEHTTSAVVQSIFVVIVVDAVAALFCMEMGW"
     gene            2240..3061
                     /locus_tag="P5537_15900"
     CDS             2240..3061
                     /locus_tag="P5537_15900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV79571.1"
                     /translation="MSTASDPAGNVIEVRGVRNQFGSQVVHDQLDLDVRRGEILSVVG
                     GSGTGKSVLLRTIVGLNRPREGRVLVFGEDLLSLPDARRKEVERRFGVLFQKGALFSS
                     LTVAENVALPLIEHAGMSRREAAELAALKIALAGLPAIAGDKFPSDLSGGMVKRAALA
                     RALALDPDILFLDEPTAGLDPIGAAAFDQLILTLRDALGLTVFIVTHDLDTIYTITDR
                     VAVLAQKKVLVNAGLDEVAATDDAWIREYFHGPRGRAAATAVAAAQAVPAATEND"
     gene            3063..4004
                     /locus_tag="P5537_15905"
     CDS             3063..4004
                     /locus_tag="P5537_15905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015914 - phospholipid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MlaD family protein"
                     /protein_id="HRV79572.1"
                     /translation="METRAHHVLIGLFTVLVVGAALLFTLWLGKSDADRQFEIYDIVF
                     QEAVSGLSKGGTVEFNGIKIGEVDSLRLDPEDARRVIARVRVDAAAPVRTDTRARLVP
                     AGITGLTMIRLTSGDDPASRHLVSEGDEVARIVAAPSPLSRLLADGEDAITNVNDLLV
                     QARELFSADNVASIGRTLGNLEQATGALAAQREDLNAALRQVTQASRDASTALAEASR
                     VLGSANKLVAVQGTQTLDSAREAMKAFERAMGTVDRLIADNRAPLDGGMRGLAEIGPA
                     VAELRSTLASLRTITRQLESRPADYLLGLEPTKEFTP"
     gene            4001..4672
                     /locus_tag="P5537_15910"
     CDS             4001..4672
                     /locus_tag="P5537_15910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-type transport auxiliary lipoprotein family
                     protein"
                     /protein_id="HRV79573.1"
                     /translation="MRSSSFPSRRDAGASRPLRVAAAAVLCAAVLLPACSVLPEAEPL
                     DVYVLPVTGDASATAVPAAAGAQAWSLRVVRPAAGVHLAGQRIVVMPEDNRVSVYQGA
                     GWSDPAPVLVRDRVLEAFRADGRVGALSSDERQLHADFELDSDLRAFQSEYRGGRPEA
                     VLRLDARLVHTASRRIVASRTFEQRQPTEDPAVPAVVQAFGTAADRLSAAVVDWTVRE
                     AAAVR"
     gene            4973..>5691
                     /locus_tag="P5537_15915"
     CDS             4973..>5691
                     /locus_tag="P5537_15915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HRV79574.1"
                     /translation="MSPKPPSAPSPRVIPIAPAALPAARRLQWRRRLFQGGFYLLFIL
                     APVFDLFRFDLEADHAWLLGFEWRLGLDDFLAKRASNVEAGTNLLLRLFLPVFGLAAV
                     VLWISWKWGRLFCGWLCPHFSIVEGLNALFVRASGKPTLWEKAPLPAVRADGSRLRRD
                     PRWWLLVAPVGLGLAFSWAVVLLTYVLPPAEIYANLAGLSFTRNQTVFLAIVTAALSV
                     DFLFARHLFCRYMCSVGVFQS"
BASE COUNT          677 a         1977 c         2139 g          898 t
ORIGIN      
        1 cgtcggggcg tggtggggtg cgccgaggcg cggtgggggc gtcggggcgt gctggggtgt
       61 gccgaggtgc ggtgggggac gtcgggggtg tcggggcgta gctaggggcg tcggtgggtg
      121 gcggggtgtg gcgggggacg tcggggtgtg gccgcgggcg tcggggaatg gtggggggcg
      181 tcggggcgtg gtggggttcg tgtaggagcg ccggcaggcg cgaaggcggc gggcgggctg
      241 gtgccacgtc gccggtagcg ccgcccgatc tgggccggcc tgcgctcggg ctggagagat
      301 tcgaccggag gcaattcaac gcatgttgta atatcccgtc tcgcttcctt ctccctctcc
      361 agcatgcccg atcttgccga acacgcccga accgtgcgcg gccgtggccg cccgcgcggt
      421 ccggacgcga actaccgtgc gcgcctgctc gacgccgcgc tcgacgcctt cggggcgcag
      481 ggcttcgagg cggcggggct acgcgcgatc gcggcggacg cgggctgcga cgtgtcgatg
      541 gtggcgcact acttcggctc caaggccgag ctgtgggccg cggtggtcga gcgtctcgag
      601 gcgcaggtgc gtgccgacct ggccgcgctc gacatgctgg cgcccgccgc ggggccgatc
      661 gagcgccgcg tcgtggcggc ggtggaggcg atgttcgtgc atgccgcgcg tcagccgcag
      721 gcgatgcgct tcgtgatgcg gcagatgacc gatccgggcg agcgcctcga cgagctcgtc
      781 gcgcgcgtgg tcgagccggt gcatgcggtc ttcctgccgg tgtggcagga ggcgatcgac
      841 gccgggctct tccacatgcg cagcgcgctg gcgctgcagg ccttcgtgtt cggcgcgatc
      901 tcctacgccg tcgcggcggc gccggtgctg gcgcgcatga gcggcggcga gatcgacctc
      961 gcgcgcctgc agcgcgagtt cggggacggt ctgttcgctc gcttcgcgcg cggccgggcc
     1021 gatgccgaag gggacgaggc cggcgagggc acacgatgag cgaggcgctg ctgcgtgagc
     1081 cccgcccggg cgaggccacc atcgacggcg agggtgcagg cgcggttctg cgcctgcgcg
     1141 gcgactggac gctggcccac cacgcggcgc tgcgccgcca ggccgaagcc ctgcgcggcc
     1201 ggctcgaagc cgcaacgcgg gtcgaggcgg gcgagctcgg caccctcgac acggccggtg
     1261 cccgcctgct gcacggcctg ctcggcggcg aacgcgtcgc ggcgctgctg gccggggacg
     1321 gcgggctgag ccgcgagcgg cgcgcgctgc tgaaggcggt ggccgaggcg atcgagggcc
     1381 gcgaggacaa gcccgcggag cccgagggca gcgcgatcgg cgacgtgctc gcgcacatcg
     1441 gccacaccat gggcgtgttc tggcgccacg tcaccggcct caccggcttc gtcggcctga
     1501 tcctcgagag cgcgctgcgc gtgagcgtgc agccgcggcg ctggcgcatg accgcgctgg
     1561 tcgccaacct cgagcgcacc ggcctggatg cggtgccgat catcgcgctg ctgaccttcc
     1621 tgatcggggc ggtggtggcc ttcctcggcg cgacggtgct ggcgaacttc ggcgccagca
     1681 tcttcacggt cgacctggtg acctactcct tcctgcgcga gttcggcgtg ctgctcacgg
     1741 cgatcatcgt cgccggccgc acggcgagct ccttcaccgc gcagatcggc tcgatgcgtg
     1801 ccaacgagga gatcgacgcg atccgtgtgc tcggcctcga tccggtcgag ctgctggtgc
     1861 tgccgcgcgt ctatgcgctg atgcttgcgc tgccgatgct gaccttcatc gcgatgctct
     1921 cgggtatcgt cggcggcatg ctggtgtcgg cgctgacgct ggacatctcg ccggtgctgt
     1981 tcctgtcgag gatcgaggac aacgtggggc tgatccactt ctgggtcggc atggcgaagg
     2041 cgccgatctt cgccttcctg atcgcggtga tcggctgcct ggagggcttc cgcgtgcagg
     2101 gcagcgcgca gtcggtgggc gagcacacca cctcggcggt ggtgcagtcg atcttcgtgg
     2161 tgatcgtggt ggatgcggtc gccgcgctgt tctgcatgga gatgggctgg tgacgggggg
     2221 gctggtgaca ggggggctgg tgagcaccgc atccgatccg gcggggaacg tcatcgaggt
     2281 gcgcggcgtg cgcaaccagt tcggcagcca ggtcgtgcac gaccagctcg acctcgacgt
     2341 gcgccgcggc gagatcctca gcgtggtggg cggctcgggc accggaaagt cggtgctgct
     2401 gcgcaccatc gtcggcctca accggccgcg cgaggggcgg gtgctcgtct tcggcgagga
     2461 cctgctgagc ctgcccgacg cgcgccgcaa ggaggtggag cgccgcttcg gcgtgctgtt
     2521 ccagaagggc gcgctgttct cgtcgctgac cgtggccgag aacgtggcgc tgccgctgat
     2581 cgagcatgcc gggatgtcgc gccgcgaggc ggcggagctg gcggcgctca agatcgcact
     2641 cgccgggctg ccggcgatcg ccggcgacaa gtttccgtcg gacctgtcgg gcggcatggt
     2701 caagcgcgcg gcgctggcgc gcgcgctcgc gctcgacccc gacatcctct tcctcgacga
     2761 gcccaccgcc ggcctcgacc cgatcggcgc cgcggccttc gaccagctca tcctgaccct
     2821 gcgcgacgcg ctcgggctca cggtgttcat cgtcacccac gacctcgaca ccatctacac
     2881 catcaccgac cgcgtcgccg tgctggcgca gaagaaggtg ctggtcaacg ccggcctgga
     2941 cgaagtcgcc gccaccgacg acgcctggat ccgcgaatac ttccacggcc cgcgcggccg
     3001 cgccgccgcc accgcggtgg ccgccgcgca ggccgtgccc gcagcaacgg agaatgactg
     3061 acatggaaac ccgcgcccat cacgtgctga tcggcctctt caccgtcctc gtcgtcggtg
     3121 ccgccttgct cttcacgctc tggctgggca agagcgacgc cgaccgccag ttcgagatct
     3181 acgacatcgt cttccaggag gcggtctccg gcctgtccaa gggcggcacg gtggagttca
     3241 acggcatcaa gatcggcgag gtcgacagcc tgcgcctcga tcccgaggac gcgcgccggg
     3301 tgatcgcgcg cgtgcgcgtc gacgccgcgg cgccggtgcg caccgacacc cgcgcccgcc
     3361 tggtgccggc ggggatcacc gggctgacca tgatccggct caccagcggt gacgatccgg
     3421 cgagcaggca tctggtctcc gagggcgacg aggtggcgcg catcgtcgcc gcgccctcgc
     3481 cgctgagccg cctgctcgcc gacggcgagg atgcgatcac caacgtcaac gacctgctgg
     3541 tgcaggcgcg cgagctgttt tccgccgaca acgtggcctc gatcgggcgc acgctcggca
     3601 acctggagca ggccaccggc gcgctcgccg cgcagcgcga ggacctcaac gccgcgctgc
     3661 gccaggtcac ccaggccagc cgcgacgcca gcacggcgct cgccgaggcc agccgggtgc
     3721 tcggctcggc caacaagctg gtggcggtgc agggcacgca gaccctggac agcgcgcgcg
     3781 aagccatgaa ggccttcgag cgcgcgatgg gcacggtcga ccgcctgatc gccgacaacc
     3841 gcgcaccgct cgacggcggc atgcgcggcc tcgccgagat cgggcctgcg gtggccgagc
     3901 tgcgcagcac gctggcctcg ctgcgcacca tcacccgcca gctcgagagc cgccccgccg
     3961 actacctgct cggccttgaa ccgaccaagg agttcacccc gtgagatcgt cgtccttccc
     4021 ttcgcgccgc gacgccggcg cctcgcgccc gctgcgggtg gccgcggcgg cggtgctgtg
     4081 cgcggctgtg ctgctgcccg catgcagcgt gctgcccgag gccgagccgc tggatgtgta
     4141 tgtgctgccg gtgacgggtg acgcgtccgc caccgcggtg ccggcggccg cgggcgcgca
     4201 ggcgtggtcc ctgcgcgtgg tgcgtccggc cgccggcgtc catctggccg ggcagcgcat
     4261 cgtggtgatg cccgaggaca accgggtgag cgtgtatcag ggtgcgggct ggagcgatcc
     4321 ggcgcccgtg ctggtgcgcg accgcgtgct cgaggccttc cgcgccgacg gccgggtggg
     4381 tgcgctgagc agcgacgagc gccagctgca tgcggatttc gagctcgaca gcgacctgcg
     4441 cgccttccag agcgaatacc gcggcggccg tcccgaggcg gtgctgcgcc tcgacgcccg
     4501 cctggtgcac accgccagcc gccgcatcgt cgccagccgg accttcgagc agcgccagcc
     4561 gaccgaggat ccggccgtgc cggccgtcgt ccaggccttc ggtaccgccg ccgaccggct
     4621 gtcggccgcg gtggtcgact ggaccgtgcg cgaggccgct gcggttcgct gagccccctg
     4681 cgccggttcg cgccttgcgg cgctcctgca ggggtccggc aacgcgcggg tttcgtgtag
     4741 ggagcgtcgc aaggcgcaca tgcggcgatt tcgatctgcc ggcctggcag atcgggcggt
     4801 gtgcgctggc gtggctggca gaggaattgg cagcgcgtgc gcctcccgct gccatctttc
     4861 gcgccgaatc gccggcctcg agcgtgcgca gtggaactgg cacgaatcgt gtttgcattt
     4921 ccaggtccgc cggcgtgcgc cggtgcttgc cgcacacacg cgaatccgct cgatgagccc
     4981 gaaaccgccc tccgcccctt ccccccgcgt catcccgatc gcgcccgcgg cgctgcccgc
     5041 cgcgcggcgg ctgcaatggc gccgccgcct gttccagggc ggcttctacc tgctgttcat
     5101 cctcgcgccg gtgttcgacc tgttccgctt cgatctcgaa gccgaccacg cctggctgct
     5161 cggcttcgag tggcggctgg ggctggacga cttcctcgcc aagcgtgcga gcaacgtcga
     5221 ggccgggacg aacctgttgc tgcgcctgtt cctgccggtg ttcgggctgg ccgcggtggt
     5281 gctgtggatc tcgtggaaat gggggaggct gttctgtggc tggctgtgcc cgcatttctc
     5341 catcgtcgag gggctcaacg cgctgttcgt ccgtgccagc ggcaagccga cgctgtggga
     5401 gaaggcgccg ctgcccgcgg tgcgggcgga tggctcccgc ctgcggcggg atccgcgctg
     5461 gtggttgctg gtggcgccgg tcggcttggg gctggcgttc tcgtgggcgg tggtgctgct
     5521 gacctacgtg ctgccgccgg cggagatcta cgccaacctc gccggcctga gcttcacgcg
     5581 caaccagacc gtcttcctcg ccatcgtcac cgccgcgctg agcgtggact tcctcttcgc
     5641 ccgccatctg ttctgccgct acatgtgctc ggtgggcgtg ttccagagct t
//
LOCUS       DAOTIN010000173         5626 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_17062_length_5626_cov_10.301921, whole genome shotgun
            sequence.
ACCESSION   DAOTIN010000173 DAOTIN010000000
VERSION     DAOTIN010000173.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 5626)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5626)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5626
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_17062_length_5626_cov_10.301921"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1229
                     /locus_tag="P5537_15920"
     CDS             <1..1229
                     /locus_tag="P5537_15920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HRV79575.1"
                     /translation="YAGKDDPTFATGEGAAWALAWFESAVPSESYVNLIPTVNGGTHE
                     SGLRAGVFEAMKSFIDHHTLLPRGVKLQQEDVCGRMSFVLSARLLDPQFQGQVKEKLN
                     SREAVKLVSSQLRDPFEIWLNNHVEAGRAIAELSIKQALARQKSAQKVEKKKTSGVAV
                     LPGKLSDCESEDLADNELFLVEGDSAGGSAKMARNKETQAILPLRGKVQNAWEIDPDR
                     LFANAEIHDIAVALGVDAHKADSDVDLSGLRYGKVVIMSDADVDGAHIQTLLLTLFFR
                     HFPKLIERGHVYVAQPPLYRVDVPAQGKKRPPRRLYALDEGELAAIRERLEKEGFKPD
                     AIEIGRFKGLGEMNPDQLRETTMDPATRRVLPVKVRSGALQDTLKMFTLLMGKGEASG
                     RRAWMEEKGDSVEADV"
     gene            1248..1427
                     /locus_tag="P5537_15925"
     CDS             1248..1427
                     /locus_tag="P5537_15925"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79576.1"
                     /translation="MNTNSNNKLTPVGALAALVLFEPDFSITRDQPAEAETRAPIDTG
                     SNLERTPNEGEDHQA"
     gene            1424..3859
                     /gene="parC"
                     /locus_tag="P5537_15930"
     CDS             1424..3859
                     /gene="parC"
                     /locus_tag="P5537_15930"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009340 - DNA topoisomerase IV complex
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HRV79577.1"
                     /translation="MSNDTPDLFGASEAPESATPLTTAVASALPATSETPATMIGGDL
                     PPPPAPPADPEPEPEDDGTLALDRYAERAYLAYAMSVVKSRALPQVEDGLKPVQRRIL
                     FAMNEMRLSSTSKHVKSARVVGDVIGKYHPHGDSSVYDAMVRVAQDFSLRYPLVDGQG
                     NFGSRDGDSAAAMRYTECRLTPIAELLLSEIDRGTVDFIPNYDGAFEEPQLLPARLPF
                     VLLNGASGIAVGMATEIPPHNLREVAEATCHLIRHPEATLEDVLGILPGPDFPGGGQL
                     ISTPDTIRDAYASGRGSLRLRARWKIEDLARGQWRAIVEELPHGVSAAQVLSEIETLT
                     NPQPRAGKKEVSQEQKNLKQLVLGVLDTVRDESSDKAPVRIVLEPKSSRQNRDEFMAV
                     LLAHTSLETSASVNMTMIGRDGRPQQKNLVQILREWIDFRYVTVERRTRHRLDEVDRR
                     IHILEGRMIAFLHIEEVIRVIRESDEPKPALIAAFGLSEIQAEDILEIRLRQLARLEG
                     FKIEKELAELRDERAGLQHLLDSRAAMTKLILKEIQDDAKKYGDDRRTLVEAVAAVAP
                     AEISVPDEPVTVIVSKNGWVRSRQGHGIDPAGITYKAGDFGFAVIETRTTWPLIVVDS
                     NGRAYTVKVSDLPGGRGDGAPITTLVEFQDGGKLAQVVTDTPDSVYFFANSGGYGFLC
                     SVADATSRQRAGKAFMSLEKGEKVLAPAKVFGDWIAAASENGRILVFPRPEMKTQSGG
                     RGVIVMALDEGEALAAVAVPADDAVLAVEGIGRGGKAVTIELKPSQREPLRHRRARKG
                     VPLTPKVKPERMR"
     assembly_gap    4151..4250
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<4251..4479)
                     /locus_tag="P5537_15935"
     CDS             complement(<4251..4479)
                     /locus_tag="P5537_15935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein MotB"
                     /protein_id="HRV79578.1"
                     /translation="MRRRRKLDEEHDNHERWLVSYADFITLLFAFFVVMYSLSSVNEG
                     KYRVLSDSLVQAFRNVNVNDSGEQIVLPKVSI"
     gene            complement(4496..5236)
                     /locus_tag="P5537_15940"
     CDS             complement(4496..5236)
                     /locus_tag="P5537_15940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein"
                     /protein_id="HRV79579.1"
                     /translation="MDKISLVGLTLGIAAILVGQVLEGGHLSSLFQPTAFMIVIGGTL
                     GAVMLQSPLRIFMQGMRMARWVFVPPAPAFDTLIEQVASWGQTARKEGLLSLENQIEA
                     LPDPFMRKGLQLLVDGIEPNRLREVLEVEIGVWENQMKMSARIWEAAGGYAPTIGILG
                     AVMGLIHVMENLSDPSRLGAGIAVAFVATIYGVGFANLVFLPIAKKLGAHIVTLTTQR
                     EMFVDGLVGIANGDNPRIIASRMQGYVA"
     gene            complement(5267..>5626)
                     /locus_tag="P5537_15945"
     CDS             complement(5267..>5626)
                     /locus_tag="P5537_15945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HRV79580.1"
                     /translation="QLVYLEDFNREEDDDYLDRHLAQEGNDPLTLLEDSDLRRRLVGA
                     IEHLPEREQLVMALYYDEELNLREIGEVLGVTESRVCQLHSQAVARLRAGVFEGGAAM
                     PAARRRGRPPKNAATGR"
BASE COUNT          942 a         1936 c         1855 g          793 t
ORIGIN      
        1 aatacgctgg caaggacgac cccaccttcg ccaccggcga aggcgcggcc tgggcgctgg
       61 cctggttcga gtcggcggtg ccgagcgagt cctacgtcaa cctgatcccg accgtgaatg
      121 gcggcaccca cgaatccggc ctgcgcgccg gcgtgttcga ggcgatgaag tccttcatcg
      181 accaccacac cctgctgccg cgcggcgtca agctgcagca ggaggacgtg tgcgggcgca
      241 tgagcttcgt gctctcggcg cgcctgctcg acccgcagtt ccagggccag gtgaaggaga
      301 agctcaactc gcgcgaggcc gtcaagctcg tctccagcca gctgcgcgac cccttcgaga
      361 tctggctcaa caaccacgtc gaggccggcc gcgccatcgc cgagctgtcg atcaagcagg
      421 cgctcgcgcg ccagaagagc gcgcagaagg tcgagaagaa gaagacctcg ggcgtcgccg
      481 tgctgccggg caagctgtcg gactgcgagt ccgaggacct cgccgacaac gagctcttcc
      541 tggtcgaggg cgactccgcc ggcggctcgg ccaagatggc gcgcaacaag gagacccagg
      601 ccatcctgcc cttgcgcggc aaggttcaga acgcctggga gatcgacccc gaccgcctct
      661 tcgccaacgc cgagatccac gatatcgcgg tggcgctcgg cgtcgatgcg cacaaggccg
      721 acagcgacgt ggacctctcc ggcctgcgct acggcaaggt cgtcatcatg tcggacgccg
      781 atgtggacgg cgcccacatc cagaccctgc tgctcacact cttcttccgc cacttcccca
      841 agctgatcga gcgtggccat gtatacgtgg cgcaaccgcc gctgtaccgc gtggacgtgc
      901 ccgcgcaggg caagaagcgc ccgcctcgcc gcctctacgc gctcgacgag ggcgagctcg
      961 cggccatccg cgagcgcctg gaaaaggaag gcttcaagcc cgacgcgatc gagatcggcc
     1021 gcttcaaggg cctgggcgag atgaaccccg accagctgcg cgagaccacc atggaccccg
     1081 ccacccgccg cgtgctgccg gtgaaggtgc gcagcggcgc gctgcaggac acgctgaaga
     1141 tgttcaccct gctgatgggc aagggcgagg cctcggggcg gcgggcgtgg atggaggaga
     1201 agggcgacag cgtcgaggcg gatgtgtgag ccccggagga cccgcagatg aatacgaact
     1261 ccaataacaa gctcacgccg gtcggcgcgc tcgccgccct ggtgctgttc gaacccgatt
     1321 tttcgatcac gcgcgatcag cctgcagagg cggaaacgcg cgcaccaatc gacacggggt
     1381 cgaacttgga gcgcacgccg aacgaaggcg aagatcacca agcatgagta acgacactcc
     1441 cgacctgttc ggcgcctctg aagcgcctga gtctgccacg ccgctgacga ccgcggtcgc
     1501 atcggcactt cccgcaacaa gcgaaacacc cgcgaccatg attggtgggg acctgccgcc
     1561 cccccctgcc ccgcccgccg acccggagcc cgaacccgag gacgacggca cgctggcgct
     1621 cgaccgctat gccgagcgtg cctacctcgc ctacgccatg agcgtggtga agtcgcgcgc
     1681 gctgccgcag gtcgaggacg gtctcaagcc cgtgcagcgc cgcatcctgt tcgcgatgaa
     1741 cgagatgcgg ctgtcgtcca cctccaagca cgtgaagtcc gcgcgcgtgg tcggcgacgt
     1801 gatcggcaag taccacccgc acggcgactc cagcgtctat gacgccatgg tgcgggtggc
     1861 gcaggacttc tcgctgcgtt atccgctggt ggacggccag ggcaacttcg gctcgcgcga
     1921 tggcgactcg gcggcggcga tgcgctacac cgagtgccgc ctgaccccga tcgccgagct
     1981 gctgctgtcc gagatcgacc gcggcacggt ggacttcatc cccaactacg acggcgcctt
     2041 cgaggagccg cagctgctgc ccgcgcgcct gcccttcgtg ctgctgaacg gcgcctcggg
     2101 catcgcggtg ggcatggcga ccgagatccc gccgcacaac ctgcgcgagg tggccgaggc
     2161 cacctgccac ctgatccgcc accccgaggc cacgctcgag gacgtgctcg gcatcctccc
     2221 cggcccggac ttccccggcg gcggccagct catctcgacg cccgacacca tccgcgacgc
     2281 ctacgcctcg ggccgcggta gcctgcgcct gcgcgcgcgc tggaagatcg aggatctcgc
     2341 ccgcggacaa tggcgcgcga tcgtcgagga gctgccgcac ggcgtctccg ccgcgcaggt
     2401 gctgtccgag atcgagacct tgaccaaccc acagccgcgc gcgggcaaga aggaggtctc
     2461 gcaggagcag aagaacctca agcagctcgt gctcggcgtc ctcgacacgg tgcgcgacga
     2521 gtccagcgac aaggcgccgg tgcgcatcgt gctcgagccc aagtccagcc gccagaatcg
     2581 cgacgagttc atggcggtgc tgctcgccca caccagcctg gagacctcgg cctcggtcaa
     2641 catgaccatg atcgggcgcg atggtcggcc gcagcagaag aacctcgtgc agatcctgcg
     2701 cgagtggatc gacttccgct acgtcaccgt cgagcgccgc acccgccatc gcctggacga
     2761 ggtcgaccgc cgcatccaca tcctcgaagg ccgcatgatc gccttcctgc acatcgagga
     2821 agtgatccgc gtgatccgcg agtcggacga gcccaagccg gcgctgatcg cggccttcgg
     2881 gctctccgag atccaggccg aggacatcct cgagatccgc ctgcgccagc tcgcgcgcct
     2941 ggaaggcttc aagatcgaga aggagctcgc tgagctgcgc gacgagcgcg cgggcctgca
     3001 gcacctgctc gacagccgcg cggcgatgac caagctgatc ctcaaggaga tccaggacga
     3061 cgcgaagaag tacggcgacg atcgccgcac gctggtcgaa gccgtggccg cagtggcgcc
     3121 ggccgagatc tcggtgccgg atgagccggt cacggtcatc gtgtcgaaga acggctgggt
     3181 gcgttcgcgc cagggccatg gcatcgaccc cgccggcatc acctacaagg ccggtgactt
     3241 cggcttcgcg gtgatcgaga cgcgcacgac gtggccgctg atcgtcgtcg acagcaacgg
     3301 ccgcgcgtac acagtgaagg tctccgacct gcccggcggg cgcggcgacg gcgcgccgat
     3361 caccaccctg gtcgagttcc aggatggcgg caagctggca caggtcgtca ccgacacgcc
     3421 ggattcggtg tacttcttcg ccaacagcgg cggctacggc ttcctgtgca gcgtcgcgga
     3481 cgccaccagc cggcaacgcg ccggcaaggc cttcatgagc ctggagaagg gcgagaaggt
     3541 gctggcgccg gccaaggtct tcggcgactg gatcgcggcg gcctccgaaa acggccgcat
     3601 cctcgtcttc ccccgccccg agatgaagac ccagagcggc ggccgcggcg tgatcgtgat
     3661 ggcgctggac gagggcgagg cgctcgccgc ggtggcagtg ccggccgacg acgcggtgct
     3721 cgccgtggaa ggcatcggcc gtggcggcaa ggcggtgacg atcgagctca agccttcgca
     3781 gcgcgaaccg ctgcgccatc gccgcgcgcg caagggcgta ccgctgacgc cgaaggtgaa
     3841 gcccgagcgc atgcgctgaa gcctgcgccc attcgcggct gccgccgctc ctacacgggc
     3901 cgaaaccgcg acgcttcatg taggagcgcc ggcaggcgcg aacacggcga tggaagcccg
     3961 cacacgcctt cttcgacgcc cgcccattcg cggctgccgc cgctcctaca cgggccgaaa
     4021 ccgcgacgct tcatgtagga gcgccggcag gcgcgaacac ggcgatggaa gcccgcacac
     4081 gccttcttcg acgcccgccc attcgcggct gccgccgctc ctacacgggc cgaaaccgcg
     4141 acgcttcatg nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn cgatgctgac
     4261 cttgggcagc acgatctgct cgccgctgtc gttgacattg acgttgcgga aggcctgcac
     4321 gagcgagtcg gagagcaccc ggtacttgcc ctcgttgacc gaggacagcg agtacatcac
     4381 cacgaagaag gcgaacagca gcgtgatgaa gtctgcgtaa gacaccagcc agcgttcgtg
     4441 gttgtcgtgt tcctcgtcga gcttgcgcct gcgccgcatc gtcggtctcc ggcgttcagg
     4501 ccacgtagcc ctgcatgcgg ctggcgatga tgcgcgggtt gtcgccgttg gcgatcccaa
     4561 ccaggccatc gacgaacatc tcgcgctggg tggtcagcgt gacgatgtgc gcgcccagct
     4621 tcttggcgat cggcaggaac accagattgg cgaagccgac gccgtagatg gtggcgacga
     4681 aggcgaccgc gatgccggca cccagccgcg aggggtcgga gaggttctcc atcacgtgga
     4741 tcaggcccat caccgcgccc aggatgccga tcgtcggcgc atagccgccg gcggcctccc
     4801 agatgcgcgc cgacatcttc atctggttct cccacacgcc gatctcgacc tcgagcacct
     4861 cgcgcaggcg attcggctcg atgccgtcga ccagcagctg caggcccttg cgcatgaagg
     4921 ggtcgggcag cgcctcgatc tggttctcca ggctcagcaa gccctccttg cgcgcggtct
     4981 ggccccagct cgcgacctgc tcgatgaggg tgtcgaaggc gggcgcaggc ggcacgaaga
     5041 cccagcgcgc catgcgcatg ccctgcatga agatgcgcag cgggctctgc agcatcaccg
     5101 cgccgagcgt gccgccgatc acgatcatga aggcggtggg ctggaacagc gaggacaggt
     5161 ggccgccctc gagcacctgg ccgacgagga tggcggcgat tccgagggtg aggccgacga
     5221 ggctgatctt gtccatggct tccgggggcg gcgctggcgg ccccgatcag cggcctgtgg
     5281 ccgcgttctt gggtgggcgc ccgcgtcggc gcgccgcggg catcgccgcg ccgccctcga
     5341 agacgccggc gcgcaggcgg gccaccgcct ggctgtgcag ctggcacacg cgcgactcgg
     5401 tgacgccgag tacctcgccg atctcgcgca ggttgagctc ctcgtcgtag tacagcgcca
     5461 tcaccagctg ctcgcgctcg ggcaggtgct cgatcgcccc gaccaggcgg cggcgcaggt
     5521 cgctgtcctc gagcagggtg agcgggtcgt tgccctcctg ggcgaggtgg cggtcgagat
     5581 agtcgtcgtc ttcctcgcgg ttgaagtcct cgagatagac gagctg
//
LOCUS       DAOTIN010000174         5504 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_17556_length_5504_cov_7.915948, whole genome shotgun sequence.
ACCESSION   DAOTIN010000174 DAOTIN010000000
VERSION     DAOTIN010000174.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 5504)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5504)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5504
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_17556_length_5504_cov_7.915948"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1495
                     /locus_tag="P5537_15950"
     CDS             <1..1495
                     /locus_tag="P5537_15950"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79581.1"
                     /translation="FPTSLPLFGDAGADGEPSVPALPALELVLPAAAAADLFALDTGA
                     ATPALRIETRPDGELRVSLDQPPPPELRAALVAALPERKAREALTRELDRFELRHRTF
                     ASPSQRGVDFRPLPLLCVRDAQGELELAERETLLDLAGFVLADQPPELPGFRPDESPG
                     AYLVDLDHGRLRIEQERGAYAVNLDLVPTTVTEADLLHWLDARLREPGTPQPQMLAWL
                     GRVLRWLERYEGHTLTALVRHRNRLADALAERLRALRENAQRQGLQRVLSGFETPACI
                     SAEYVFMFGRGLYPARPPYYTGRHRFVKHYYGVIGDLQEAGARQTDHEYHCAVALDGL
                     PQLRHWVRNLARFPEFSFWLPTASDRFYPDFVAELEDGRLLVVEYKGEGYKSADDAIE
                     KQRVGELWARLSGNLFLLAVERDAQGRGVAEQLRACVGGVAIAEHARVVALVDIAFDG
                     GAVPAGSVGTVVSVYDEGAGYAVEFGAVAGEMGVVFAAAGALRRVSS"
     gene            1549..1845
                     /locus_tag="P5537_15955"
     CDS             1549..1845
                     /locus_tag="P5537_15955"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79582.1"
                     /translation="MVDYLLATAHPDGASKARFFLARGARSEAWEVFAKTLVEHARLN
                     SVASVRDDPAGRARLFQVDCHVRMPDDSTPCIRTVWELRAGAACPRLVTAYPAA"
     gene            complement(1895..3460)
                     /locus_tag="P5537_15960"
     CDS             complement(1895..3460)
                     /locus_tag="P5537_15960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004368594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C metal-binding domain-containing protein"
                     /protein_id="HRV79583.1"
                     /translation="MNSRAKPTMPAMQQPVLTDADLQTIMDRAFQSAVGVIIASNDIA
                     AVIAHLRQALRPLAALVVNEQGGTPAEIERAAQGMAVRLAYELWNATPIPENHFRPRK
                     LAPPERNAPCPCGSQRKYKQCCGAGNEGPLILPPDEMLGRVLDHLPRTRLGEPVSRGV
                     SPHILALVASRWCDEQRFDDVIALLEPLFIDLGKLDERAADAANILMNCYLARQQYDA
                     RNALVERLKKSHNRVLRSTGLQREATVCSDRGDIRDAWRAFNEARHLTPDDPSLSHLE
                     VLLLLAEGRDIEARERADYWTAVLAADPRHDNRALIEALHTLGAEAAADDPLDDLPQD
                     YPERRLVLHIALEDIDPPIWRRVEVENTLSFEALHHVIQAAMGWEDAHLHEFKVGDHR
                     IGMGDDYDNPFDEGVLPGEDVELGQVIGRRRSFIYEYDFGDGWRHRITIEKRLPSDPL
                     RKPAALLDGERACPPEDCGGVSGYYNILEAKRSPRSADSQEILDWLGPYKPESFKLTK
                     HQKQVDALFKRIR"
     gene            3626..4816
                     /locus_tag="P5537_15965"
     CDS             3626..4816
                     /locus_tag="P5537_15965"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HRV79584.1"
                     /translation="MAQLVLHPGKERSLFRRHPWIFAGSVDRLDGRARPGDTVTVVTA
                     EGKALARAAWSPSSQIRARVWSFDAEAAIDHAFFKRAVAASVARRVAIPALRGQEGMR
                     LIHGESDGLPGVIADRYGDVVVLQLTSAGADKWRDAIVAGLVQATGCAAVYERSDSEV
                     RGLEGLESRTGCAHGELPAGGLTIVENGVRMEVDVEGGHKTGFYLDQRDNRLLTGQLA
                     GGRAVLNCFCYTGGFSLQALAGGAASVLSIDSSGPALASARRNLALNPQLDASRAEWQ
                     EADVFKALRALKEEGRKFDLIVLDPPKFAPSAAHAERAARAYKDINLFGFRLLNPGGI
                     LMSYSCSGGIGQELFQKIVAGAAIDAGVDARILYRLSAAPDHPIGLAVPEGEYLKGLA
                     CQVG"
     gene            4897..5223
                     /locus_tag="P5537_15970"
     CDS             4897..5223
                     /locus_tag="P5537_15970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HRV79585.1"
                     /translation="MKIRFRSLLAAAAAALLGAGGLFVSGASAGERVRVEEIRQLRES
                     GQILSAEDILARSRALQPGQVVGLELEREDGRWIYEVKLIDERNRVHELELDAANGEV
                     LERKEK"
     gene            5227..>5504
                     /locus_tag="P5537_15975"
     CDS             5227..>5504
                     /locus_tag="P5537_15975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004312952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV79586.1"
                     /translation="MRLLVVEDDAALGERLRTRLVAEGYAVDLARDGIDGAHLGATEP
                     YDAVILDLGLPGKPGLAVLREWRAAANRVPVLILTARDGWAERVEGLQA"
BASE COUNT          743 a         1820 c         2023 g          918 t
ORIGIN      
        1 gtttccgacc agtctgccgc tgttcggcga cgcgggtgcg gatggcgagc cgtccgtgcc
       61 ggccttgccc gcgctggagc tggtgctgcc ggcggccgcg gcggccgacc tgttcgcgct
      121 cgacacgggg gcggcgacgc cggccctgcg catcgagacc cggccggatg gcgaactgcg
      181 ggtgagcctg gatcagccgc cgccgcccga gctgcgcgcc gcgctggtcg cggcgctgcc
      241 cgagcgcaag gcgcgcgagg cgctgacgcg cgaactcgac cgcttcgaac tgcgccaccg
      301 gaccttcgcc tcgccctcgc agcgtggtgt ggacttccgc ccgttgccct tgctgtgtgt
      361 ccgtgatgcg cagggcgagc tggagctggc cgagcgcgag acgctgctcg atctcgccgg
      421 cttcgtcctc gccgatcagc cgcccgaact tcccggcttt cggcccgacg aatcgccggg
      481 cgcctacctg gtcgacctgg accacggccg tctgcgcatc gagcaggaac gcggcgctta
      541 cgcggtgaac ctggatctgg taccgaccac ggtgaccgag gccgacctgc tgcactggct
      601 ggatgcccgc ctgcgcgaac ccggcacgcc gcagccgcag atgctcgcct ggcttggccg
      661 tgtgctgcgc tggctggagc gctacgaggg ccacacgctg accgccctgg tgcgccaccg
      721 caaccggctc gccgacgcgc tcgccgaacg cctgcgcgcg ctgcgcgaga acgcgcagcg
      781 ccagggcctg cagcgcgtgc tgagcggctt cgagacgccg gcctgcatca gcgccgaata
      841 cgtcttcatg ttcggccgcg ggctgtatcc ggcgcgcccg ccgtattaca ccggccgcca
      901 ccgcttcgtg aagcactact acggggtgat cggcgatctg caggaggcgg gggcgcgcca
      961 gaccgaccac gagtatcact gcgcggtcgc gctcgacggt ctgccgcagc tgcggcactg
     1021 ggtgcgcaac ctggcgcgct ttccggagtt ctcgttctgg ctgccgaccg cgagcgaccg
     1081 cttctatccc gacttcgtcg ccgaactgga ggatggtcgc ctgctggtgg tcgagtacaa
     1141 gggcgagggc tacaagagcg cggacgacgc gatcgagaag cagcgcgtgg gcgagctgtg
     1201 ggcgcgcctg agcggcaacc tgttcctgct cgccgtggag cgggacgcgc aggggcgtgg
     1261 cgtggccgag cagctgcgcg cctgcgtcgg cggtgttgcg atcgcggagc atgcccgggt
     1321 ggttgcgttg gtcgacatcg ccttcgacgg tggcgcggtg cctgccggca gcgtgggtac
     1381 ggtggtgtcg gtgtatgacg aaggtgccgg ctacgcggtc gagttcggcg cggtggcggg
     1441 ggagatgggc gtggtcttcg ccgctgccgg tgcgctgcgc agggtgtcgt cgtgataggg
     1501 gcacgcaagc tgccgggcgt ggagtgcgct caggtcgaat acagaaaggt ggtcgattac
     1561 ctgctggcca cagcccaccc ggacggcgca tcgaaggcgc gcttctttct cgcccgcggc
     1621 gcgcgttcgg aggcctggga ggtcttcgca aagacgctgg tcgagcacgc gcgccttaac
     1681 tcggttgcca gcgttcgtga cgacccggcg gggcgggcac gtttgttcca ggtcgattgt
     1741 catgtccgga tgccggacga ctcgacaccg tgcattcgca ccgtttggga attgcgcgcg
     1801 ggcgcagcct gtcctcggtt ggtgactgcc taccccgctg cgtgaccagt gcgcgagcca
     1861 gcactccggt tggctggccc cgcgcgtctg gggcctatcg aatgcgcttg aacagcgcgt
     1921 ccacctgctt ctggtgcttt gtgagcttga aggattccgg cttgtacggc cccagccagt
     1981 cgagaatctc ctggctatcg gcgctgcgcg gcgagcgctt ggcctcgaga atgttgtagt
     2041 agccggacac gccgccgcag tcttccggcg ggcaggcgcg ttcgccgtcg agcagggcgg
     2101 cgggtttgcg cagcggatcg ctcggcaggc gcttttcgat ggtgatgcgg tggcgccagc
     2161 cgtcgccgaa gtcatactcg tagatgaagc tgcggcggcg gccgatgacc tgcccgagtt
     2221 cgacgtcctc gccgggcagg accccttcgt cgaacgggtt gtcgtagtcg tcgcccatgc
     2281 cgatgcgatg gtcgccgacc ttgaactcgt gcaggtgcgc atcctcccag cccatcgcgg
     2341 cctggatcac gtggtgcagc gcctcgaagc tgagggtgtt ctccacttcg acacggcgcc
     2401 agatcggcgg gtcgatgtct tccagggcga tgtgcagcac cagccggcgc tccgggtagt
     2461 cctggggcag atcgtccagc gggtcgtccg cagccgcctc tgccccgagg gtgtgcaggg
     2521 cttcgatcag ggcacggttg tcgtggcgcg ggtcggcggc gagcacggcc gtccagtagt
     2581 ccgcgcgctc gcgtgcctcg atgtcgcgtc cctcggcgag caacaacaac acttccagat
     2641 gcgatagcga cgggtcgtcc ggggtcagat ggcgcgcctc gttgaaggcc cgccaggcgt
     2701 cgcggatgtc gccgcggtcg gaacagaccg ttgcctcgcg ttgcagtccg gtactgcgca
     2761 acacgcggtt gtgtgacttt ttcaaacgct cgaccagcgc gttgcgtgcg tcgtactgct
     2821 gccgtgcgag atagcagttc atcaggatgt tggcggcgtc ggcggcgcgt tcgtcgagct
     2881 ttccgaggtc gatgaacagg ggctcgagca aggcgatcac gtcgtcgaag cgctgctcgt
     2941 cgcaccaacg gctggcgacc agcgccagga tgtggggtga gacgcctcgc gagacaggct
     3001 cgccgagccg cgttcggggc aggtgatcga gcacccgccc gagcatttcg tcgggcggca
     3061 ggatcagcgg gccttcgtta cctgcgccgc aacattgctt gtacttgcgt tgcgagccgc
     3121 aggggcaggg cgcgttgcgc tcggggggcg caagcttgcg cggacggaag tgattctcgg
     3181 gaatcggggt ggcgttccac agctcgtacg cgagtcgtac cgccatgcct tgggcagcgc
     3241 gctcgatttc ggccggtgtg ccaccttgtt cgttgacgac cagtgcggcc agcggtcgca
     3301 gggcctggcg caggtgggcg atcacggcgg cgatgtcgtt ggacgcgatg atgacgccga
     3361 cagcgctctg gaaggcgcga tccatgattg tctggaggtc ggcatcagtc agcacgggtt
     3421 gttgcatcgc tggcatcgtc ggtttggcgc ggctgttcat ggattcatct gactccctgg
     3481 gcgtggggcg aaccttagct ttttgtcgcg cgttacgtcc atcgactttg tcgatgtcgc
     3541 tgcacgcatg gtgctgcgct tgggccatgg cacgacgagc cgttacactc gccggcctga
     3601 ttgcatcgcc ccttggaatc ccgccatggc ccaactcgtc ctccaccccg gcaaggaacg
     3661 ctcgctgttc cgccgccacc cctggatctt cgccggctcg gtggatcgcc tcgacggccg
     3721 cgcgcggccg ggcgacacgg tgacggtggt gaccgccgag ggcaaggcgc tggcgcgcgc
     3781 ggcgtggtcg ccgtcctcgc agatccgcgc gcgggtgtgg agcttcgatg ccgaggcggc
     3841 gatcgaccat gccttcttca agcgcgcggt ggcggcctcg gtggcgcggc gggtggcgat
     3901 cccggcgctg cgcgggcagg agggcatgcg tctgatccac ggcgagtccg acggcctgcc
     3961 cggcgtgatc gccgaccgct acggcgacgt ggtggtgctg cagctcacca gcgcgggcgc
     4021 ggacaagtgg cgcgacgcca tcgtcgccgg cctggtgcag gcgaccggct gcgcggcggt
     4081 gtatgaacgc tccgactccg aggtgcgcgg gctggaaggt ctggagtcgc gcaccggctg
     4141 tgcgcacggc gagctgccgg cgggcgggct caccatcgtc gaaaacggcg tgcgcatgga
     4201 ggtggacgtg gaaggcgggc acaagaccgg cttctacctc gaccaacgcg acaatcggct
     4261 gctcaccggc cagctcgccg gcgggcgcgc ggtgctcaac tgcttctgct acaccggcgg
     4321 cttctcgctg caggcgctcg cgggaggcgc ggcctcggtg ctgtcgatcg actcctccgg
     4381 cccggcgctg gcgtcggcgc gccgcaacct cgcgctcaac ccccagctcg acgcgagccg
     4441 cgccgagtgg caggaggcgg acgtgttcaa ggccctgcgt gcgctgaagg aagagggccg
     4501 caagttcgac ctgatcgtgc tcgacccgcc caagttcgcg ccctcggctg cgcacgccga
     4561 gcgcgccgcg cgcgcctaca aggacatcaa cctgttcggc ttccggctgc tcaacccagg
     4621 cggcatcctg atgagctact cgtgctcggg cggcatcggc caggagctgt tccagaagat
     4681 cgtcgccggc gcggcgatcg acgccggggt ggatgcgcgc atcctctacc ggctctcggc
     4741 cgcaccggac catccgatcg ggctggcggt gccggaaggc gaatacctca aggggctggc
     4801 ctgccaggtg gggtgagcgg ggcagggacc gtgttcagct tgcgttcaga ttgcggcggg
     4861 cacactgtct gcaccgaaac ccgccggaga gtgaagatga agatccgatt ccgttccctg
     4921 ctggccgcgg ccgcggccgc gctgctcggc gccggcgggc tgttcgtctc gggtgcgagc
     4981 gccggcgagc gcgtgcgggt ggaagagatc cgccagctgc gcgagagcgg gcagatcctc
     5041 tcggccgagg acatcctcgc gcgcagccgc gccctccagc ccggccaggt cgtcggtctg
     5101 gagctcgagc gcgaggacgg gcgctggatc tacgaggtca agctgatcga cgagcgcaac
     5161 cgggtgcacg agctcgagct cgacgccgcc aacggcgaag tgctcgaacg caaggagaag
     5221 tgagcgatgc gcctgctcgt ggtcgaggac gatgcggcgc tcggcgagcg cctgcgcacc
     5281 cggctggtcg ccgaaggcta cgcggtcgac ctcgcgcgcg acggcatcga cggcgcccat
     5341 ctgggcgcga ccgagcccta tgacgcggtg atcctcgacc tcggcctgcc cggcaagccc
     5401 gggctcgcgg tgctgcgcga gtggcgcgcg gcggcgaacc gcgtgccggt gctgatcctc
     5461 accgcgcgcg acggctgggc cgagcgcgtc gagggcctgc aggc
//
LOCUS       DAOTIN010000175         5487 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_17626_length_5487_cov_9.780376, whole genome shotgun sequence.
ACCESSION   DAOTIN010000175 DAOTIN010000000
VERSION     DAOTIN010000175.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 5487)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5487)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5487
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_17626_length_5487_cov_9.780376"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..824)
                     /locus_tag="P5537_15980"
     CDS             complement(<1..824)
                     /locus_tag="P5537_15980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV79587.1"
                     /translation="MSGLRILVADDDLTTALLMQAALVRAGFAVTLAADGEEAVQAFA
                     QAPFDMVLLDVDMPRLDGFAVCRELRRRGGEELPILMVTGMDDTASIEAAFEAGATDF
                     INKPITWALLGHRVRYVLRATRAAAALRSANARNAAMLDALPDTLVRIDGRNQIVEVR
                     TDPGMECCCAPSAGQALAAAYPPEVIAILERALDDTRRSGKPRTVEFQLGGAEDRPSH
                     HEARLSSIDGSEALCLLRDITERKEYERRIHRLAYYDSLTGLANRRGFIERLEREIA"
     gene            complement(821..3589)
                     /locus_tag="P5537_15985"
     CDS             complement(821..3589)
                     /locus_tag="P5537_15985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HRV79588.1"
                     /translation="MSVQSPNDTYISLGEKLRRVNLQALGLAVGLLALVITLASLVIS
                     ALALESNTRVMTRVLADNAAASLMFLDKEAAARVLATLEHLPDVRGAAIFDTQLAEFV
                     RYGRFLAEGEGRQKPSLSSEHAQFRLDTLHMTQPIVENGNVIGVLDLDLDLQPLYTQV
                     FAHTSIVAAAALLALWLATGMLRRLNGVVLRPLTTLSALMERVAHTEDYGARAEPSRI
                     TELDSLAIGFNRMLGQIAERDARLAAHRDHLEDEVATRTEELLRAKEAAEAASQAKSD
                     FLATMSHEIRTPMNGVLGMTELLLDSDLNHEQRHFAEAVENSARHLLGIINDILDFSK
                     IESGQLELESVEFELGELLEGTLAMFAQPAEKKGLELVADLPPEARRCVLGDPFRLRQ
                     IVGNLINNAVKFTERGEIVVRARLLGEGAEDCRLRISVEDTGIGIPPHAQQKIFDQFS
                     QLDGSTTRQFGGTGLGLAICRRLVGLMGGEIGVDSQPGKGARFHFDLRLPSGHSTPEA
                     LRCDVALDHVRTLVVDDNATNREILLRQLQGWGMHVECAADGAGALGLLAHTTAAGEG
                     FDLAVLDMHMPHMDGLQLASSIRANPALAGVRLVVLTSSYSSASVRERERAGILRCVH
                     KPIRQAELHEVICSALRGPRDTGGDARTPTAAPIALAGRVLLAEDNPVNQQVGEAMLA
                     KLGLAVQFAANGEEAVRLAQAEAFDLILMDCHMPVMDGYEASAAIRAGVRAHRVPIIA
                     LTANVMEGNRERCLAAGMDDFLGKPYSLGQLHAVLRRWMGAVADTAPADDKPPAAAAA
                     QAADEEAAIDRGFLEQFRELDPAGGLALAERIVGVYLDSCGKTFAQIEEAAAAGDGEG
                     LRRAAHSLKSSSGNVGAKPLYALLRELEGLGRDGDIEAARARLDDLRRAFARACAELR
                     ALRAEIGP"
     gene            complement(3806..4639)
                     /gene="metF"
                     /locus_tag="P5537_15990"
     CDS             complement(3806..4639)
                     /gene="metF"
                     /locus_tag="P5537_15990"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HRV79589.1"
                     /translation="MKPEISIEFFPPTTAEGADKLRATREKLAALKPAFFSVTYGAGG
                     STRERTFSTVKEIAAAGHEAAPHLSCVGSSRDSIREILQEYADAGIRRIVALRGDLPS
                     GAGAAGEFRYANELVEFIRAETGDRFHIEVAAYPEWHPQAKSPKDDLDAFKRKVDAGA
                     NSAITQYFYNLDAYLHFVDAVRKMGVDVPIVPGIMPIGSFSKLARFSDACGAEIPRWM
                     RKTFESYGDDSDAIRAFGLDVVTDLCEKLLAAGAPGLHFYSMNMAGPTTEICRRLGLT
                     A"
     gene            complement(4636..>5487)
                     /locus_tag="P5537_15995"
     CDS             complement(4636..>5487)
                     /locus_tag="P5537_15995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HRV79590.1"
                     /translation="MNSFHARQGKPRPAAQGKGPADRHGLLRVDQLLVAQGLAASRTA
                     ARALIEAGRVSHEGQPVAKPALELLPDARLTVMPADSDRFVSRGALKLEGALARSGLD
                     VRGAICLDIGQSTGGFTDCLLQAGAAKVVGVEVGHDQLHPRLRADGRCVTFEGLNARQ
                     LGAAELGEHYPPQGFDLLVCDASFISLALLLPQWAALLAPAGHVLALVKPQFEVGPQG
                     LGKGGIVRDPARYAEVEARLRIAADAAGLLILDWFDSPITGGDGNREFFFHAIRRPGG
                     DTHRSKP"
BASE COUNT          743 a         1809 c         2083 g          852 t
ORIGIN      
        1 gcgatctcgc gctcgaggcg ctcgatgaag ccgcggcggt tggccagccc ggtgaggctg
       61 tcgtagtagg cgaggcgatg gatgcggcgc tcgtattcct tgcgctcggt gatgtcgcgc
      121 agcaggcaca gcgcctcgct gccgtcgatc gagctcagcc gtgcctcgtg gtggctgggg
      181 cggtcttccg cgccgccgag ctggaattcc accgtgcgcg gcttgccgct gcgccgcgtg
      241 tcgtcgagcg cgcgttccag gatggcgatc acttcaggag ggtaggccgc ggccagcgcc
      301 tgccccgcac ttggcgcgca gcagcattcc atgcccgggt cggtgcgcac ctcgacgatc
      361 tggttgcgac cgtcgatgcg caccagggtg tccggcaggg cgtcgagcat cgccgcgttg
      421 cgcgcgttgg cgctccgcag ggcggcagcg gcgcgggtcg cgcgcagcac gtagcgcacg
      481 cggtggccga gcagcgccca ggtgatgggc ttgttgatga agtcggtggc gccggcctcg
      541 aaggcggcct cgatcgaggc ggtgtcgtcc atgcccgtca ccatcaggat cggcagctcc
      601 tcgccgcccc gtcggcgcag ctcgcggcac accgcgaagc cgtccaggcg cggcatgtcc
      661 acgtcgagca ggaccatgtc gaagggcgcc tgcgcgaagg cctgcacggc ctcctcgccg
      721 tcagcggcca gcgtgaccgc gaagcccgcg cgcacgagcg cggcctgcat gagcagggcg
      781 gtggtcaggt cgtcgtcggc gaccaggatg cggagtccgc tcatggcccg atctccgcgc
      841 gcagtgcgcg gagctccgcg caggcgcgcg cgaaggcccg gcgcagatcg tcgaggcggg
      901 cgcgtgcggc ttcgatgtcg ccgtcgcggc cgagaccctc gagctcgcgc agcagggcgt
      961 agagcggctt cgcgccgacg ttgcccgagc tcgacttgag gctgtgcgcg gcgcggcgca
     1021 ggccctcgcc gtcgccggcg gccgcagcct cttcgatctg ggcgaaggtc ttgccgcagc
     1081 tgtccagata gacgccgacg atgcgctcgg cgagcgcgag cccgcccgcg gggtcgagct
     1141 cgcggaactg ctcgaggaag ccgcgatcga tggcggcttc ctcatccgcg gcctgcgcgg
     1201 ccgcggcggc gggcggcttg tcgtccgcag gtgcggtgtc ggccacggcg cccatccaac
     1261 gccgcagcac tgcatgcagc tgtccgagcg agtagggctt gccgaggaag tcgtccatgc
     1321 cggcggcgag gcagcgttcg cggttgccct ccatcacgtt ggcggtgagg gcgatgatgg
     1381 ggacgcggtg cgcccgcaca cccgcgcgga tcgctgcgct ggcctcgtag ccgtccatca
     1441 ccggcatgtg gcagtccatc aggatgaggt cgaaggcctc ggcctgcgcc aggcgcaccg
     1501 cctcctcgcc gttggcggcg aactgcaccg cgaggccgag cttggcgagc atggcctcgc
     1561 cgacctgctg gttgaccggg ttgtcctcgg ccagcaacac gcgcccggcg agcgcgatcg
     1621 gggcggccgt cggcgtgcgg gcgtcgccgc cggtgtcgcg cgggccgcgc agcgcgctgc
     1681 agatcacctc gtgcagctcg gcctggcgga tgggcttgtg cacacagcgc aggatgccgg
     1741 cgcgttcgcg ctcgcggacg ctggcgctgg agtagctcga ggtcaatacc accaggcgta
     1801 cgccagcgag cgcggggttg gcgcggatcg agctggccag ctgcaggccg tccatgtgcg
     1861 gcatatgcat gtcgagcacg gcgaggtcga acccctcgcc cgccgcggtc gtgtgcgcga
     1921 gcagcccgag cgcgcccgcg ccgtcggcgg cgcactccac gtgcatgccc cagccctgca
     1981 gctggcgcag caggatctcg cgattggtgg cgttgtcgtc caccacgagg gtgcgtacgt
     2041 ggtcgagcgc cacgtcgcag cgcaaggcct ccggtgtgct gtggccggag ggcaggcgca
     2101 ggtcgaaatg gaaacgcgcg cctttcccgg gctggctgtc cacgccgatc tcaccgccca
     2161 tcagacccac caggcggcgg cagatcgcca ggccgaggcc ggtgccgccg aactggcggg
     2221 tggtggagcc gtcgagctgg gagaactggt cgaagatctt ctgttgcgca tggggtggga
     2281 tgccgatgcc ggtgtcttcg acgctgatgc gcaagcggca gtcctcggcg ccctctccga
     2341 gcaggcgggc gcgtaccacg atctcgccac gctcggtgaa cttgaccgcg ttgttgatca
     2401 ggttgccgac gatctggcgc agacggaagg ggtcgccgag cacgcagcgt cgcgcttcgg
     2461 ggggcaggtc ggcgaccagc tccaggcctt tcttctcggc cggctgggcg aacatcgcca
     2521 gcgtgccttc gagcaactcg ccgagctcga actccacgga ctcgagttcg agttgaccgg
     2581 actcgatctt cgagaagtcg aggatgtcgt tgatgatgcc gagcaggtgg cgggcggagt
     2641 tctccactgc ctcggcgaaa tgacgctgct cgtggttgag gtcgctgtcg agcagcagct
     2701 cggtcatgcc gagcaccccg ttcatcggcg tgcggatctc gtggctcatg gtggcgagga
     2761 agtcgctctt ggcctggctg gccgcctcgg cggcctcctt ggcgcgcagc agctcctcgg
     2821 tgcgcgtcgc gacctcgtcc tcgaggtggt cgcggtgggc ggccaggcgt gcgtcgcgct
     2881 cggcgatctg gccgagcatg cggttgaagc cgatcgccag cgagtcgagc tcggtgatgc
     2941 ggctcggctc ggcgcgcgcg ccgtagtcct cggtgtgggc gacgcgctcc atcagcgccg
     3001 acagcgtggt cagcgggcgc agcaccacgc cgttgagccg ccgcagcatc ccggtggcga
     3061 gccagagcgc gagcagcgca gcggcggcga cgatcgaggt gtgggcgaag acctgggtat
     3121 agagcggctg gaggtcgaga tcgaggtcga gcacgccgat cacgttgccg ttctcgacga
     3181 tcggctgggt catgtgcagc gtgtcgaggc ggaactgagc atgctcggag gacaggctcg
     3241 gcttctgtcg gccttcgcct tcggcgagga agcggccgta gcgcacgaac tcggcgagct
     3301 gggtatcgaa gatcgcagcg ccgcgcacgt cgggcaggtg ttcgagggtc gcgaggacgc
     3361 gcgcggccgc ctccttgtcg aggaacatca ggctcgcggc ggcgttgtcg gcgagcaccc
     3421 gcgtcatcac gcgggtgttg ctctcgagcg cgagcgcgct gatcaccagg ctggcgaggg
     3481 tgatcaccaa cgcgagcagg cccacggcga ggccgagggc ctgcaggttg acccggcgca
     3541 gcttctcgcc gaggctgata taggtgtcgt tcggggattg gacggacatc atcggaagcc
     3601 tgggcagcgg tatgcgacgg ctgccggagc gcccccagga ctggctgccg aggggccgct
     3661 ctggaggcgg atcatgatca gggcgggttg gggaggcgga gcaatcggtt tttttgctgc
     3721 tttgcacact ttacgtccgg cagcccccgc ccttgaggcg caaatgtcac attccgcgag
     3781 cacttgcgcg agaggattgc ccgaatcagg ccgtcagccc cagccgccgg cagatctcgg
     3841 tcgtcgggcc ggccatgttc atgctgtaga aatgcaggcc gggcgcgccc gcggcgagca
     3901 gcttctcgca caggtcggtg accacgtcga ggccgaaggc gcggatggcg tcgctgtcgt
     3961 cgccgtagct ctcgaaggtc ttgcgcatcc agcgcgggat ctcggcgccg caggcatccg
     4021 agaagcgcgc cagcttgctg aagctgccga tcggcatgat gccgggcacg atcggcacgt
     4081 cgacgcccat cttgcgcacc gcgtcgacga agtggaggta ggcgtcgagg ttgtagaagt
     4141 actgggtgat tgccgagttg gcgccggcgt cgaccttgcg cttgaaggcg tcgaggtcgt
     4201 ccttcgggct tttcgcctgc gggtgccatt cggggtaggc ggcgacctcg atgtggaagc
     4261 ggtcgccggt ctctgcgcgg atgaactcga cgagctcgtt ggcgtagcgg aattcgcccg
     4321 ccgcgcctgc gcccgagggc aggtcgccgc gcagggcgac gatgcggcgg atgccggcgt
     4381 cggcgtattc ctgcaggatc tcgcggatgc tgtcgcgcga cgagcccacg caggacaggt
     4441 gcggcgcggc ctcgtggccg gcggcggcga tctccttgac ggtgctgaag gtgcgctcgc
     4501 gggtggagcc gccggcgcca taggtcaccg agaagaaggc cggcttcagc gcggcgagct
     4561 tctcccgggt ggcgcgcagc ttgtcggcgc cctcggcggt ggtgggcggg aagaactcga
     4621 tggagatttc gggtttcatg gcttgcttcg atgggtgtcg ccgcccggcc tgcggatggc
     4681 gtggaagaag aattcgcggt tgccgtcgcc gccggtgatc ggcgagtcga accagtcgag
     4741 gatgagcagc ccggcggcgt ccgcggcgat gcgcaggcgg gcctcgactt cggcgtagcg
     4801 cgccgggtca cgcacgatgc cgcccttgcc caggccttgc gggccgacct cgaactgcgg
     4861 cttgaccagc gccagcacgt ggccggcggg cgcgagcagc gcggcccact gcggcagcag
     4921 cagggcgagc gagatgaagc tggcgtcgca caccagcagg tcgaagccct gcggcgggta
     4981 gtgctcgcca agttcggcgg cgccgagctg gcgggcgttg aggccttcga aggtgacgca
     5041 gcggccgtcg gcgcgcaggc gcggatggag ctggtcgtgg ccgacctcca ccccgaccac
     5101 ctttgccgcg ccggcctgca gcaggcagtc ggtgaagccg ccggtggact ggccgatgtc
     5161 gaggcagatt gcgccgcgca cgtccagccc gctgcgcgcg agcgcgcctt cgagcttgag
     5221 cgcgccgcgc gagacgaagc ggtcgctgtc ggcgggcatc accgtgaggc gcgcgtcggg
     5281 cagcaactcg agcgccggtt tggcgaccgg ctggccctcg tggctcaccc gcccggcctc
     5341 gatcagcgcc cgcgccgcgg tgcgcgaggc cgccagcccc tgcgccacca gcagctggtc
     5401 cacgcgcagc aggccgtgcc ggtccgccgg gcccttgccc tgcgcggccg gccgcggctt
     5461 gccctggcgg gcgtggaagg agttcat
//
LOCUS       DAOTIN010000176         5265 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_18615_length_5265_cov_10.064875, whole genome shotgun
            sequence.
ACCESSION   DAOTIN010000176 DAOTIN010000000
VERSION     DAOTIN010000176.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 5265)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5265)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5265
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_18615_length_5265_cov_10.064875"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..553)
                     /locus_tag="P5537_16000"
     CDS             complement(<1..553)
                     /locus_tag="P5537_16000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004307177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylesterase"
                     /protein_id="HRV79591.1"
                     /translation="MSPHSSPGLVFDTPPIELETGPDPRYSVIWMHGLGADGGDFEPV
                     IPALGLPRSPAVRFIFPHAPYRAVTCNAGYVMRAWYDIVSLAPHSRQIDEAGLLDSRA
                     LVRQLIEREAERGVPAERVILAGFSQGGAVAYLTGLTHPEPLAGIIALSTYLPSPGLL
                     IDGFEEANRRTPVFAAHGTHDDVV"
     gene            633..851
                     /locus_tag="P5537_16005"
     CDS             633..851
                     /locus_tag="P5537_16005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3820 family protein"
                     /protein_id="HRV79592.1"
                     /translation="MNPEHLELLLSREMPFGKYKGRVIADLPGYYLAWLARKGFPPGQ
                     LGQLLALMHELDHNGLGGLLEPLRRARS"
     gene            1017..2141
                     /locus_tag="P5537_16010"
     CDS             1017..2141
                     /locus_tag="P5537_16010"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004307180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HRV79593.1"
                     /translation="MPRFLHTADWQIGRQYARFAPEDALALAEARLSAVERLADIAHQ
                     EAVDAVLVAGDVFDAQTVSDRTIRRLFNAMGAYAGPWVLIPGNHDAALAESVWTRARR
                     LGAVAANVHLALSAQVMAFPERGFAVLPAPLTQRQTAADETAWFDHAVTAPGLVRVGL
                     AHGSVQGVLAEGIDSPNPIAADRAGRAALDYLALGDWHGTRRIDARTWYSGTPEQDRF
                     KANDPGNVLLVDIPAAGAEPKVEVRAVGRHLWIELEESLAVASDLERTIARLQALPEL
                     AVVDLSLAGELHLLGRQQLEAALSVAEARFRSLRTDLSRLRLQPTEDDLAALHADGYV
                     GRVIAELREEQEGGNAELAREAMAILAALLLETQGQGETA"
     gene            2138..4792
                     /locus_tag="P5537_16015"
     CDS             2138..4792
                     /locus_tag="P5537_16015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004307182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HRV79594.1"
                     /translation="MRLLRLKVEQLRRFRQPVEIRDLDAGINLFTGPNESGKSTLVRA
                     IRAAFFERYKSSSVEDLQPWGDSAAAPTVELEFEWQGKRWKLVKSFLKRKRCDVSVDG
                     VAFSGEEAEDKLADLLGFEFPGRGASRPEHWGIPGLLWIEQGAGHEIHKPVEHAGSHL
                     KSVLGSSLGEVTSSAGDALIARITKERARLLTATGRPTGDFATALEAHERLEREHADL
                     QGRIRQYRQQVDRLGQLRDEQARDDGERIWEAYRQQARAAEVRLVEVLAWQREQERDQ
                     QALQVCQASVRTSLDLLGRFEAQRKDLHKRAADRDVAAQALAAQEARRPAVERALADA
                     RTAFEAARVAVRLAREQQQRKDLARELEQADAELAGLDQALARARELHEALLRQRGLR
                     QTLHIDAKALARLRKAEDELARLAIRQEAVATRLQFDLREPGAVTLAGEPLHGQGERL
                     LLEPAEIVLGQLGSLRILPGGDDIADLVRKRQGLDDDRASLLSVLGVASLAAADIRHE
                     QCRELDGTIRRDESVLESLAPEGLEALAGRRQLKQARREELARLIAALPEPQQGGLSV
                     SRAEVQLDGAGESLKAAEAAEAGFRSALLLATQALESARSEWSRLDGELQGADRRQHE
                     KLAAEQLLELRANENRLEQALRERQKQIDLANPGVLRQDVERFTRSADAAEKAAEQRR
                     LELERLKASLEALGAEGLEERSAELDVELARAVRRKDELGRRAGALDLLLVRLTDHRL
                     QLTRQLQAPLQRHLNRYLQLLFPEASLSVDEALVPEILVRQGLDGEERGRFAELSFGA
                     REQMGLISRLAYADLLREAGRPTLIILDDALVHSDVERLGNMKRVLFDAAQRHQILLF
                     SCHPDSWRDLGVAPRDVAGLGMPAAPSP"
     gene            4806..5084
                     /locus_tag="P5537_16020"
     CDS             4806..5084
                     /locus_tag="P5537_16020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002928273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VF530 family protein"
                     /protein_id="HRV79595.1"
                     /translation="MTAPQPNNPLHGLTLEQILVQLVERLGWATLGRRVSIRCFNHEP
                     SIASSLKFLRRTPWARAQVEALYLDTLQQPGAGGAGGKIRVPRSDIDP"
BASE COUNT          799 a         1801 c         1965 g          700 t
ORIGIN      
        1 cgacgacgtc gtcgtgggtg ccatgcgcgg cgaagaccgg cgtgcggcga ttcgcctcct
       61 cgaagccgtc gatcagcagc ccggggctgg ggaggtaggt cgacagcgcg atgattcccg
      121 cgagcggctc ggggtgggtg agcccggtca ggtaggccac ggcgccgccc tgcgagaagc
      181 ccgcgaggat gacgcgctcg gcgggcacgc cgcgctcggc ttcgcgttcg atcagctggc
      241 ggacgagcgc gcgcgaatcg agcagcccgg cctcgtcgat ctggcggctg tgcggggcga
      301 gcgagacgat gtcgtaccag gcgcgcatga catagccggc gttgcaggtc accgcacgat
      361 agggggcgtg ggggaagatg aagcgcaccg cagggctgcg gggcaggccc agcgccggga
      421 tgaccggctc gaagtcgccg ccgtccgcgc ccaggccgtg catccagatg acactgtagc
      481 ggggatcggg tccggtctcg agctcgatgg gcggggtgtc gaagacgagg cctggggagg
      541 agtgggggct caagcgggtc accttgtggg agagtggagc gtcggtgcgc gcggctgcgc
      601 accttgtggg ctacgaaaag cggatcggac ggatgaatcc tgaacacctg gagctgctgc
      661 tcagccgcga gatgcccttc ggcaagtaca aggggcgggt gatcgcggat ctgccgggat
      721 actacctcgc gtggctcgcc cgcaagggct tcccgccggg gcagctgggc cagctgctgg
      781 cgctgatgca cgagctcgac cacaacggcc tcggcggcct gctggagccc ttgcgtaggg
      841 cgcggagcta gggctgtggc gcggtcgggc ggcgtgtaac atgccggcct gtgacaaatg
      901 ggtcgctgca gcggccgggc ttgccgacgg gggctgcaaa atcgtgcgcc ccgcgctccg
      961 ggccgcgcac gcaggacttc tcgctggagc ttttcctcaa atacgggggc cgcacgatgc
     1021 cgcgctttct tcataccgcc gattggcaga tcggccgcca gtacgcgcgc ttcgcgcccg
     1081 aggacgcgct ggcgctggcc gaggcgcgcc tgtcggcggt cgagcgcctg gccgacatcg
     1141 cgcaccagga ggcggtggat gcggtgctgg tggccgggga cgtcttcgat gcgcagacgg
     1201 tgtccgatcg cacgatccgc cgcctgttca acgccatggg ggcgtacgcg gggccgtggg
     1261 tgctgatccc cggcaaccac gacgccgcgc tggccgagag cgtatggacg cgtgcgcgtc
     1321 gcctcggcgc cgtggcggcc aacgtgcatc tggcgctgag cgcgcaggta atggcgttcc
     1381 ccgagcgcgg tttcgccgtg ctgccggcgc cgctcaccca gcgccagacc gcggccgacg
     1441 agaccgcgtg gttcgaccac gcggtcacgg cgccggggct ggtgcgtgtc ggcctcgccc
     1501 acggcagcgt ccagggcgtg ctcgccgagg gcatcgactc gcccaacccg atcgccgccg
     1561 accgcgccgg ccgcgccgcg ctggattacc tcgcgctcgg cgactggcac ggcacgcggc
     1621 ggatcgacgc gcgcacctgg tacagcggca cgcccgagca ggaccgcttc aaggccaacg
     1681 atcccggcaa cgtgctgctg gtggacatcc ccgcggcggg cgccgaaccg aaggtggagg
     1741 tccgggcggt ggggcggcac ctctggatcg agctggagga gagcctggcg gtagcctcgg
     1801 acctcgagcg cacgatcgcc cgcctgcagg ccttgcccga gctcgccgtg gtcgatctga
     1861 gcctggccgg cgagctccac ctcctcggca ggcagcagct cgaggccgcg ctgtcggtgg
     1921 cggaggcgag gttccgcagc ctgcgcaccg acctgtcgcg gctgcgcctg cagcccaccg
     1981 aggacgacct cgccgccctg catgcggacg gctacgtggg cagggtgatc gccgagctgc
     2041 gcgaggagca ggagggcggg aacgccgagc tcgcccgcga ggccatggcc atcctcgccg
     2101 cgctgctgct ggagacgcag ggccagggag agacggcatg aggctgctgc gcctgaaggt
     2161 cgaacagctg cgccgcttcc gccagccagt cgagatccgc gacctcgacg ccggcatcaa
     2221 cctgttcacc ggacccaacg agtcgggcaa gagcaccctg gtgcgcgcga tccgcgcggc
     2281 gttcttcgag cgttacaagt cgtccagcgt ggaggacctg cagccctggg gcgattcggc
     2341 cgccgcgccg acggtcgagc tggagttcga gtggcagggc aagcgctgga agctggtcaa
     2401 gagcttcctc aagcgcaagc gctgcgacgt cagcgtcgac ggcgtcgcgt tcagcggcga
     2461 ggaggcggag gacaagctcg ccgatctgct cggcttcgag tttcccgggc gcggggccag
     2521 ccggccggag cactggggca ttcccggact gctgtggatc gagcagggcg ccgggcacga
     2581 gatccacaag ccggtcgagc acgccggcag ccacctgaaa tccgtcctgg gcagcagcct
     2641 cggcgaggtg accagcagcg cgggggacgc gctgatcgcg cgcatcacca aggagcgcgc
     2701 ccgcctgctg accgccacgg gccggcccac cggagacttc gccacagcgc tggaggcgca
     2761 cgagcgcctc gagcgcgagc acgccgacct acagggtcgg atccggcagt accgccagca
     2821 ggtcgatcgg ctcgggcaac tgcgggatga acaggcgcgc gacgacggtg agcgcatctg
     2881 ggaggcgtac cggcagcagg ccagggcggc cgaggtccga ctggtcgagg tgctggcctg
     2941 gcagcgcgag caggagcgcg accagcaggc cttgcaggtc tgccaggcga gcgtgcgcac
     3001 gagcctcgac ctgctcggcc gcttcgaggc gcagcgcaag gatctgcaca agcgcgccgc
     3061 ggaccgcgac gtggccgcgc aggcgctcgc cgcgcaggag gcgcgcaggc cggccgtgga
     3121 gcgtgcgctc gccgacgccc gcacggcctt cgaggcggcc agggtggcgg tccggctggc
     3181 gcgcgagcag cagcagcgca aggacctggc acgcgagctg gagcaggccg acgccgagct
     3241 cgccggcctg gaccaggcac tggcacgcgc ccgcgagttg cacgaggcgc tgctgcggca
     3301 gcgtgggttg cggcaaaccc tgcacatcga cgccaaggcg ctcgcgcgcc tgcgcaaggc
     3361 cgaggacgag ctcgcccgcc tcgcgatccg ccaggaggcg gtcgccaccc gcctgcagtt
     3421 cgacctgcgc gagcccgggg cggtcacgct ggcgggtgag cccttgcatg gacagggcga
     3481 gcgcctgctg ctcgagccgg ccgagatcgt cctcgggcag cttggaagcc tgcgcatcct
     3541 gcccggcggc gacgacatcg ccgatctggt ccgcaagcgc caggggctgg acgacgaccg
     3601 cgcgagcctg ctgtccgtgc tcggcgtggc ctcgctggcc gcggcggata tccgccatga
     3661 gcagtgccgc gagctcgacg gcaccatccg gcgcgacgag tcggtgctgg agtcgctcgc
     3721 gcccgagggc ctggaggcgc tcgccgggcg caggcagctc aagcaggcgc gccgcgagga
     3781 gctggcgagg ctgatcgcgg cgctccccga gccgcagcag ggcggcctgt cggtttccag
     3841 ggcggaggtg cagctggacg gcgccggcga atccctcaag gccgccgagg cggccgaggc
     3901 gggtttccgc agcgcgctcc tgctcgccac gcaggcgctg gagagtgccc gcagcgaatg
     3961 gagccggctg gacggcgaac tgcagggtgc ggatcgcagg cagcatgaaa agctcgctgc
     4021 agagcagctg ctcgagctgc gcgccaacga gaaccggctc gagcaggccc tgcgcgaacg
     4081 gcagaagcag atcgacctcg ccaacccggg ggtcctgcgc caggacgtcg agcgcttcac
     4141 gcgcagtgcg gacgcggccg agaaggccgc cgagcagcgt cgcctcgagc tcgagcgcct
     4201 gaaggccagc ctggaggcgc tcggcgccga gggcctggag gagaggagcg cggagctcga
     4261 cgtcgagctg gcgcgggcgg tgcgtcgcaa ggacgagctc gggcgccgcg ccggcgcgct
     4321 cgatctcctg ctcgtgcgcc tgaccgatca ccgcctgcag ctcacccgcc agctgcaggc
     4381 gccgctgcag cgccacctga accgatacct gcagctgctg ttcccggagg ccagcctgag
     4441 cgtcgatgaa gcgctcgtgc cggagatcct ggtgcgccag gggctggacg gggaagagcg
     4501 cggccgcttc gccgagctga gcttcggcgc gcgcgagcag atgggcctga tcagtcgcct
     4561 cgcctacgcc gacctgctgc gcgaggcggg gcgcccgacc ctgatcatcc ttgacgatgc
     4621 cctggtgcac agcgacgtcg agcgtctcgg caacatgaag cgcgtgttgt tcgacgccgc
     4681 acagcgccac cagatcctgc tgttcagctg ccatcccgac agctggcgtg acctcggcgt
     4741 ggcgccccgc gacgtggccg gcctgggtat gccggcagcc ccctccccct gaaggcgaac
     4801 ccgccatgac cgccccgcaa cccaataatc ccctgcacgg cctcaccctc gagcagatcc
     4861 tcgtccaact cgtggaacgc ctcggctggg ccacgctcgg ccggcgggtg agcatccgct
     4921 gctttaacca cgagcccagc atcgcctcca gcctcaagtt cctgcgccgc acgccctggg
     4981 cgcgcgcgca ggtcgaggcc ctctacctcg acaccttgca gcagcccggt gcggggggcg
     5041 cggggggcaa gatccgcgtg ccgcgaagcg acatcgaccc ataagaatct tcgattcact
     5101 ttgtgttgac ggattttctc gggtctctat aatgcgcggc ttcccgaacg cgacagcgaa
     5161 tcggcgaaac cggaaagcag cagattcttt ccttgccgcg agtcggcaga tctttaaaaa
     5221 cttggacaac cgataagtgt gggtgcttgg ttgttgcggt cggcg
//
LOCUS       DAOTIN010000177         5200 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_18900_length_5200_cov_6.634402, whole genome shotgun sequence.
ACCESSION   DAOTIN010000177 DAOTIN010000000
VERSION     DAOTIN010000177.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 5200)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5200)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5200
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_18900_length_5200_cov_6.634402"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..185)
                     /locus_tag="P5537_16025"
     CDS             complement(<1..185)
                     /locus_tag="P5537_16025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79596.1"
                     /translation="MARPLPLALPSQPRSPTSPRKGALAHALCAAALAFAALWPAANP
                     AHAAGEPVALNFQNAEI"
     gene            complement(185..718)
                     /locus_tag="P5537_16030"
     CDS             complement(185..718)
                     /locus_tag="P5537_16030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-1,2-mannosidase"
                     /protein_id="HRV79597.1"
                     /translation="MSSPFLPSPIPLVSSLRALALPAWLLALAFCAWVAADLFWQFAA
                     PTAVAAAARHEPDARKVAARIGLHVGRTAAVPDKVPARVATPDALYTVTGIATGFGAL
                     PGFVILQADDGSTFSLSPGQVLPDGRRLVRLLPEAAEFELDGRHSMLALPARGGASSE
                     PFRPPTPVADGGPRRDH"
     gene            complement(858..2912)
                     /locus_tag="P5537_16035"
     CDS             complement(858..2912)
                     /locus_tag="P5537_16035"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79598.1"
                     /translation="MKLPLIGVSALSALSIFVVSACVGGGNDGGGTPAETVPPSEPDN
                     AAPSLAAAPLRGEFISRATFANPHAHIPAQCYIETSHGTQNACLFCHTDGVAELGLGN
                     NNPHAGGNPNVGNLQAEYAFGVVNYPFTINSSVTPWINTLRPEALRNALDATGDDPAR
                     WDMQAWVREDNWSAAFAQRKGSVADWDSGTDGPFRLFPALAPADLPAQDDGFVRSATA
                     ARGLFTDAHGRNTGWRAVNFMPYGIFTPLTGSVSGIYLRLAEPFMKNAQGVFDLEIYV
                     ANLDLVERNIQDRLAGETRYLGAAAGVPIVRGQYPLGTEFAHPLHYVDVAADGTSAAP
                     SPFPGLRARRVKEVRWMYNAREWHPEEFGLALKDESAPVYASRDQGWIENGTGWLLAG
                     WIEDAAGRLRPQTPAELTQCVGCHSGNVRQSDIGQNAVFTSGTGNTIDATWSLPRKFA
                     GDAGWREMDYLGYRADATAAASSTPGTLATPEPHNRKLGKGEFRVFLDYVVGASLYGD
                     MPETIERFLAERITLAEGYAANWPQLDAAVAARDAGAIRDLQRQRQALMRAFTARGGH
                     LAANGSLRQEIFLPSAEDALAAAARYRQVVRTQRYEFGKDVFAETPFTLRYFRTAETA
                     YPHQDGRPYALGELITDRPINENVADFTFGIGITPTLIDEERSFGAGGSFLADYVPLL
                     RP"
     gene            complement(3043..4962)
                     /locus_tag="P5537_16040"
     CDS             complement(3043..4962)
                     /locus_tag="P5537_16040"
                     /inference="COORDINATES: protein motif:HMM:NF017591.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF839 domain-containing protein"
                     /protein_id="HRV79599.1"
                     /translation="MSHIARHPLALTTLAAAIALSLSACNDDDVAAPAFKSIAFSATP
                     VAKTETEMLDTYSTSVATITYEDGSTKDFPLQYNVLFRNTDQNNEVKGKNYAAAQLFN
                     VDMEPIIDPNGDPVIAETADANSLLKIDGKLMLVNHWEYDDVLADGGDAYKAANWYSR
                     MPMSMNLSELTQAADGKLSLVSQKPIDFSSVNGGWIFCFGSQTPWNTHLGGEEDYDLY
                     FIPGEAAYSTTEAGLKAMSEVYFGGKKTANPYHYGYATEVARKADGSYTVDKLYNMGR
                     GTWEAAIFAKDGRTAFFGDDGAYSGMFMFVGEKANDPKAGGTIYAAKWNQTSADGSDG
                     GTADIVWVKLGSATHAEAKALIDSGITLGDIFETSLTEQTGAGWVATRAGSSQTVWIK
                     LKPGMEKAAAVLETRRYAAYLGATTEFTKGEGVAINHADKKLYYAMSRIEGSMKANDG
                     GPVDHIRLKENKAGATYTLMMAGGQKDGTGATINSDYVPTKALVEANLLGRPIAADAN
                     GNTADVDYVANTDNVFFSEKMRTLFIGEDSGMHVNNYVWAYNVDTQKLTRILNVAAGG
                     ESTGLQAVEDMNGFAYLMSNNQHQGDWISSQNADLTARLEAKAADLFGTNKYGTLNYR
                     LTANVGYIGGLPAIK"
     gene            complement(5013..>5200)
                     /locus_tag="P5537_16045"
     CDS             complement(5013..>5200)
                     /locus_tag="P5537_16045"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79600.1"
                     /translation="RGSQRAVVGEDRGGVGHRASHFVGLWIIPVQGAKAYDCLEVHAA
                     RLIAALSSYLLTNPKHP"
BASE COUNT          742 a         1586 c         1949 g          923 t
ORIGIN      
        1 tcgatctcgg cgttctggaa gttcagcgcc accggctcgc cagcggcgtg cgccgggttg
       61 gcggcgggcc agagcgcagc gaaggcgagc gcagccgcgc acagcgcatg cgcgagggcg
      121 cccttgcgag gcgaggtggg ggagcgtggc tgacttggga gggcgagggg gagggggcgg
      181 gccatcagtg atcgcgtctg ggcccgccgt cggcgacggg cgtgggtggg cggaaaggct
      241 cgctcgacgc gccgccgcgg gcgggcaggg cgagcatgct gtggcggcca tcgagctcga
      301 attcggcggc ctcgggcagc agacggacca gcctgcgccc gtcgggcagg acctggccgg
      361 ggctcaggct gaaggtggag ccgtcgtcgg cctgcaggat cacgaagccg ggcagggcgc
      421 cgaagccggt ggcaatgccg gtgaccgtgt agagcgcatc cggggttgcg acgcgcgcag
      481 ggaccttgtc ggggaccgct gcagtgcgac cgacgtgcag cccgatgcgc gcggctacct
      541 tgcgcgcgtc gggctcgtgc cgtgccgctg cagcgaccgc cgtgggcgcg gcgaactgcc
      601 agaaaaggtc cgctgccacc caggcgcaga aggccagtgc cagcagccag gcgggcaagg
      661 ccagcgcgcg caaggaagaa accagcggaa tcggggacgg cagaaagggg ctggacatcg
      721 ggatgatcgg cgacctgggg cgtcggggcg ctctctaagc ccgggaggac gggcggcaag
      781 tatatgccag cggctcgatt gtcgccgcat tcccgctcgg gaacgcggtg acgatcgggc
      841 agggctgcgt ggccgtctca gggacgcaaa aggggaacgt agtcggcgag gaagctgccg
      901 ccggccccga agctgcgctc ctcgtcgatc agcgtcgggg tgatgccgat gccgaaggtg
      961 aagtcggcca cgttctcgtt gatcggacga tcggtgatca gctcgccgag cgcatagggc
     1021 cggccgtcct ggtgcgggta cgcggtctcg gcggtgcgga aatagcgcag ggtgaacggg
     1081 gtctctgcga acacgtcctt gccgaactcg tagcgttgcg tgcgaacgac ctgccggtag
     1141 cgtgccgccg cggcgagggc atcctcggcg ctggggagga agatctcttg gcgcagactg
     1201 ccgttggcgg cgaggtgccc gccgcgtgcg gtgaaggcgc gcatcagcgc ctggcgctgg
     1261 cgctggaggt cgcggatcgc tccggcgtcc ctcgccgcca ccgcggcgtc gagctgcggc
     1321 cagttcgcgg cgtagccttc tgcgagcgtg atgcgctcgg cgaggaagcg ctcgatcgtc
     1381 tcgggcatgt cgccgtacag cgaggcgccg accacgtagt cgaggaagac acggaattcg
     1441 cccttgccga gcttgcggtt gtgcggctcg ggtgtcgcga gcgtgccggg cgtcgaactc
     1501 gccgcggccg tcgcgtcggc gcggtagccg aggtagtcca tctcgcgcca gccggcatca
     1561 ccggcgaact tgcgcggcag gctccaggtg gcgtcgatcg tgttgccggt gccggaggta
     1621 aacaccgcgt tctggccgat gtcggactgg cgcacgttgc ccgagtggca gccgacgcac
     1681 tgggtcagtt ccgccggtgt ctgggggcgc agccgtcccg cggcgtcctc gatccaccct
     1741 gcgagcagcc agcccgtgcc gttctcgatc cagccctggt cgcggctggc gtaaaccggc
     1801 gcggattcgt ccttgagtgc gagaccgaac tcttccggat gccattcgcg cgcattgtac
     1861 atccagcgca cctccttgac ccggcgcgct cgcaggccgg ggaaggggct gggcgctgcg
     1921 ctcgtgccgt cggccgcgac gtccacatag tgcagcgggt gggcgaactc ggtgccgagc
     1981 gggtactggc cgcggacgat cggcacgccg gcggcggctc cgaggtagcg ggtctcgccg
     2041 gcgaggcggt cctggatgtt gcgttcgacg aggtcgaggt tggcgacata gatctcgagg
     2101 tcgaagacgc cttgtgcgtt cttcatgaag ggctcggcca ggcgcaggta gatccccgac
     2161 acgctgcccg tgagcggggt gaagatgccg tagggcatga agttcaccgc ccgccagcca
     2221 gtgttgcgac cgtgtgcatc ggtgaacagg ccgcgtgcag cggtggcgct gcgcacgaag
     2281 ccgtcgtcct gcgccggcag gtcggcggga gcgagcgcgg gaaagaggcg gaaggggccg
     2341 tccgtgccgc tgtcccaatc ggccacggag cccttgcgct gggcgaaggc ggcggaccag
     2401 ttgtcctcgc gcacccaggc ctgcatgtcc cagcgcgcgg gatcgtcgcc cgtggcgtcg
     2461 agcgcgtttc gcagcgcctc ggggcgcagg gtgttgatcc agggggtgac gctggagttg
     2521 atcgtgaacg ggtaattgac caccccgaag gcgtattcgg cctgcaggtt gccgacgttc
     2581 gggttgccgc cggcgtgcgg attgttgttg cccaggccaa gctcggcgac gccgtcggta
     2641 tgacagaaca ggcaggcgtt ctgggtgccg tggctggtct cgatgtagca ctgcgccggg
     2701 atgtgggcgt gggggttggc gaacgtggcg cgactgatga actcgccccg cagcggggcc
     2761 gcggcgaggc tcggcgccgc gttgtccggc tcgctcggcg ggaccgtctc cgccggtgtg
     2821 ccgccgccgt cattgccacc gccgacacag gcggacacga cgaagatgct gagtgcgctg
     2881 agtgcgctga cgccgatgag cgggagtttc atcttgggta ggtccgacag gaatcgaaat
     2941 aggaacgccc ggggccgcat gctgctgcag tcccggagca gggtgcgatc ggtgggcgcg
     3001 cgcccggtcc cggtccgcgg gtgaggcgcg cgccgggccg ccttacttga tcgcgggcag
     3061 gccgccgatg tagccgacgt tggcggtgag gcggtagttc agggtgccgt acttgttcgt
     3121 gccgaacagg tcggccgcct tggcctcgag cctcgcggtc aggtcggcgt tctggctcga
     3181 gatccagtcg ccctggtgct ggttgttgct catgaggtag gcgaagccgt tcatgtcctc
     3241 gaccgcctgc agcccggtcg actcgccgcc ggcggcgacg ttgaggatac gggtcagctt
     3301 ctgggtatcg acgttgtagg cccacacgta gttattgacg tgcatgcccg agtcctcgcc
     3361 gatgaagagc gtgcgcatct tctcggagaa gaaaacgttg tcggtgttgg cgacgtagtc
     3421 gacgtcggcg gtgttgccgt tggcgtccgc ggcgatcggg cgtccgagca gattggcttc
     3481 caccagggct ttggtcggca cgtagtcgga gttgatcgtg gcgcccgtgc cgtccttctg
     3541 gccgccggcc atcatcagcg tataggtcgc accggccttg ttctccttca ggcggatgtg
     3601 gtcgacgggg ccgccgtcgt tcgccttcat cgagccctcg atgcggctca tcgcgtagta
     3661 cagcttcttg tcggcgtggt tgatcgcgac gccttcgccc ttggtgaact cggtggtggc
     3721 gccgaggtag gcggcgtagc ggcgggtctc gagcactgcg gcagccttct ccatgcccgg
     3781 cttgagcttg atccacacgg tctgcgagga gccagcgcgg gtcgccaccc agccggcccc
     3841 ggtctgctcg gtcagtgagg tctcgaagat gtcgcccagg gtgatgccgc tgtcgatcag
     3901 cgcctttgct tcggcgtggg tggcgctgcc cagcttcacc cagacgatgt ctgcggtgcc
     3961 gccgtcgctg ccgtctgccg aggtctggtt ccacttcgcg gcgtagatcg tgccgcccgc
     4021 cttgggatcg ttcgccttct cgccgacgaa catgaacatg cccgaatagg cgccgtcgtc
     4081 gccgaagaag gcggtgcggc cgtccttggc gaagatcgcc gcctcccagg tgccgcgacc
     4141 catgttgtag agcttgtcga ccgtgtagct gccgtctgcc ttgcgcgcga cctcggtggc
     4201 gtagccgtag tggtaggggt tggcggtctt cttgccgccg aagtagacct cgctcatcgc
     4261 cttcaggccc gcctctgtgg tggagtacgc ggcttcgccc gggatgaagt agaggtcata
     4321 gtcctcctcg ccgccgaggt gggtgttcca gggcgtctgc gaaccgaaac agaagatcca
     4381 gccgccattg acgctggaga agtcgatcgg cttctggctg acgaggctga gctttccgtc
     4441 cgcggcctgg gtgagctcgg acaggttcat gctcatcggc atgcggctgt accagttggc
     4501 cgccttgtag gcatcaccgc cgtcggcgag cacgtcgtcg tactcccagt ggttcaccag
     4561 catgagcttg ccgtcgatct tcagcaggct gttggcgtcg gcggtctcgg cgatgaccgg
     4621 atcgccgttg gggtcgatga tcggctccat gtcgacattg aacagctggg ccgcggcata
     4681 gttcttgccc ttgacttcgt tgttctggtc ggtgttcctg aaaaggacgt tgtactgcag
     4741 cgggaagtcc ttcgtgctgc cgtcctcgta ggtgatggtc gccacggagg tgctgtaagt
     4801 gtcgagcatc tcggtctcgg tcttcgccac cggggtggcc gagaaggcga tcgatttgaa
     4861 ggcgggggcg gcgacgtcgt cgtcgttgca ggcggacagc gagagcgcga tcgcagcggc
     4921 gagcgtggtc agggcgagcg ggtggcgggc aatgtgcgac atggaatcct cgtcgggaat
     4981 ggaaggcgag cggattcttg ccgcgggatg tttcaggggt gttttggatt ggttaaaaga
     5041 taggagctca gcgccgcaat gagccgggcg gcatgcacct cgaggcagtc ataggctttc
     5101 gctccctgaa ctgggataat ccacagtcca acaaaatggc tcgcccgatg tccgaccccg
     5161 ccccgatctt cgccgacgac ggcccgctgg ctgccgcgat
//
LOCUS       DAOTIN010000178         5114 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_19335_length_5114_cov_9.008895, whole genome shotgun sequence.
ACCESSION   DAOTIN010000178 DAOTIN010000000
VERSION     DAOTIN010000178.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 5114)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5114)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5114
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_19335_length_5114_cov_9.008895"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            268..1449
                     /locus_tag="P5537_16050"
     CDS             268..1449
                     /locus_tag="P5537_16050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HRV79601.1"
                     /translation="MNSRALTHLALVASLLLFALVAGAAEVVRFGYLELSEDPRYDER
                     KAFFRTLSRPLGAPFAGAEVALRESRFVGQTIGVSFDIVRARGADAPALLAELEKLHA
                     EGVRHFLIDAPGKVVAELASATRGRELLLFNVSAPDDALRQAQCQAHLYHTIPNHGMQ
                     ADALAQFLVAKKWRNVLLLQGPRDEDKLVGAAFENSARRFGLKIVDRKDFVLSNDPRQ
                     RELGNVGLLTAGGDYDVVFVADSDGEFARSVPYDTVRPRPVVGAEGLVAEAWHWAWPR
                     HGAPQLTSRFEKQARRHMGSADWAAWVAVKAVVEAVVRTGNAPFDKLVAYLGGEEITI
                     DGFKGNRLYFRDWDRQLRQPLLIATHNAVIERAPLQGFLHQTNNMDTLGFDRRDSRCK
                     P"
     gene            1604..2413
                     /locus_tag="P5537_16055"
     CDS             1604..2413
                     /locus_tag="P5537_16055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV79602.1"
                     /translation="MSPVHAWLALQAVASREIAKFVRQGGRLASALVRPLLWLVVFAA
                     GFQNVFGVSIIPPYDTYIPYQTYIVPGLLGMVLLFNGMQSSLAMVYDREMGVMRLLLT
                     APLPRWYLLLCKLLAGTLLSVLQAYVFLAVAALFDVGVPWSGWLYALPVLVLAGMMLG
                     ALGLLLSVNIRQLENFAGTMNFVIFPMFFLSPALYPLWKLEESGATVIHFLATWNPFT
                     HAVEAIRFALHGQVAVHSLAIVAGCLAVFFLLAAWGYDPQRGLLRRTGKPG"
     gene            2496..4478
                     /locus_tag="P5537_16060"
     CDS             2496..4478
                     /locus_tag="P5537_16060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional anthranilate synthase component I
                     family protein/class IV aminotransferase"
                     /protein_id="HRV79603.1"
                     /translation="MPAPSAAPPIDSDSFALLDDCHATAAAPSSRLYGGLVRVHRCAD
                     PSTLEAMWAAVDADLRAGLHAVVLADYEWGVRLNGVVAEGPGPGAGPGAGGSLRVLMF
                     ATLARRSAAEVEAWLAEAEAREAESPAVAPAPAGAGEDARRAGPAPAGALGLRASVDR
                     AAFEEAIARIHAAIAEGETYQVNYSYRLDLETFGSPLALYRRLRARQPVAFGALIRLP
                     AEAGGPDWVLSCSPELFLRHHDGVLQARPMKGTAARSGDDAADALAARRLAADAKNRA
                     ENLMIVDLLRNDLGRVARTGSVRVPALFEVERYPTVLQMTSTVAAELPADVGFPALLR
                     ALFPCGSITGAPKHRTMQLITELETTPRGLYTGSLGWIDAPRPGQACGDFCLSVAIRT
                     LTLERIEQGADALAGARHRGRMGVGAGIVIDSAAADEYAECRLKARFLSALDPGFALF
                     ETMYATREAGVRQLDRHLARLEASAAALDFVFERASVEAALGGQLAALPPATPSRLRL
                     ALHKDGRLELTAAALEALPPGAVTVLLAERPLDDPHGLGAYKTTLRARYDEGLRAALA
                     AGAFDTLFFDSASRLTEGGRSNVFLLLDGEWRTPPAGRGVLPGTMRAALLEDPAWAAR
                     EAELRVEDLLRAQRIVLTNALRGAVEARLAGAGSRD"
     gene            complement(4494..>5114)
                     /locus_tag="P5537_16065"
     CDS             complement(4494..>5114)
                     /locus_tag="P5537_16065"
                     /inference="COORDINATES: protein motif:HMM:NF017545.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VPLPA-CTERM sorting domain-containing protein"
                     /protein_id="HRV79604.1"
                     /translation="YLNNLNQTSYKMEGSWQVQSSSDDDYMGFVFGYQNSSNFYLFDW
                     KQGTQGYVGRTAAEGMTIKKFAGATGNGLNDLSLEEFWENQVNFGDMSVLATNHSGTA
                     GWADNALYDFLLEFNLTPGVIRVVVKQGASTLWDTTVSDSAFTSGQFGFYNNSQEQVR
                     YAGFEQEGGVIVDPNPVPEPASLALLGLGLGGLAATRRRKSRTQPA"
BASE COUNT          654 a         1830 c         1849 g          781 t
ORIGIN      
        1 acggcacccg tcgcgcgttg gggttggatg taggagcggc ggcagccgcg aacggcaacg
       61 gcgctcggtg ccggtcggtc gcgtgccccg cagcgcggtg atcgacgatt gaggccgctt
      121 tcgcgcctgc cggcgctcct acataaaccc tcgcgcgtcc ggaaggaatg taagagcggc
      181 ggcagccgcg aacggtaacc gccgcgcgtc gggaagggac gtaggagcgg cggcagccgc
      241 gaacagggac gatcgatgga gatgaacatg aattcgcgtg ccttgacgca cctggccctg
      301 gtggcctcgc tgctgttgtt cgcgctcgtc gccggggccg cggaggtggt ccgtttcggc
      361 tacctggagc tcagcgagga cccgcgctac gacgagcgca aggccttctt ccgcaccttg
      421 tcgcgcccgc tcggtgcgcc cttcgccggt gcggaggtgg cgctgcgcga gtcgcgcttc
      481 gtcggccaga cgatcggggt gagcttcgac atcgtgcgtg cgcgcggtgc cgacgcgccc
      541 gcgctgctcg ccgagctgga gaagctgcac gccgagggcg tgcgccactt cctgatcgac
      601 gcgccgggca aggtggtggc cgagctcgcc tccgccaccc gcggccgcga gctgctgctg
      661 ttcaacgtct cggcgcccga cgacgcgctg cgccaggcgc agtgccaggc ccacctctac
      721 cacacgatcc ccaaccacgg catgcaggcc gacgcgctcg cccagttcct ggtggcgaag
      781 aagtggcgca acgtgctgct gctgcagggg ccgcgcgacg aggacaagct cgtcggtgcc
      841 gccttcgaga actcggcgcg ccgcttcggg ctgaagatcg tcgacagaaa ggacttcgtc
      901 ctcagcaacg acccgcgcca gcgcgagctc ggcaacgtcg gcctgctcac cgccggcggc
      961 gactacgacg tggtcttcgt cgccgacagc gacggcgagt ttgcgcgcag cgtgccctac
     1021 gacaccgtgc gcccgcgccc ggtggtgggc gccgagggcc tggtcgccga ggcctggcac
     1081 tgggcgtggc cgcgtcacgg cgcgccgcag ctcaccagcc gcttcgagaa gcaggccagg
     1141 cgccacatgg gcagcgccga ctgggcggcc tgggtggcgg tgaaggcggt ggtcgaggcg
     1201 gtggtgcgca ccggcaacgc gcccttcgac aagctcgtcg cctacctcgg cggcgaggag
     1261 atcaccatcg acggcttcaa gggcaaccgc ctgtacttcc gcgactggga ccgccagctg
     1321 cgccagccgc tgttgatcgc gacccacaac gcggtgatcg agcgcgcgcc gctgcagggc
     1381 ttcctgcacc agaccaacaa catggacacg ctcggcttcg accgccgcga cagccggtgc
     1441 aagccgtgac gggggcgagg ggcgggtggc ggaggaggtg ggggatgatt cggcacggga
     1501 cgagcggggc gtgcgcgggt tcgggcacga gggcgccggc gcggccccgc gcggtcgagg
     1561 ctgctccggg ggcggccgga gcgggcttgc tggaggcgct cgcatgagcc ccgttcatgc
     1621 gtggctcgcg ctgcaggcgg tcgccagccg cgagatcgcc aagttcgtcc gccagggcgg
     1681 ccggctggcc tcggcgctgg tgcggccgct gctgtggctg gtggtgttcg ccgccggctt
     1741 ccagaacgtg ttcggggtgt cgatcatccc gccctacgac acctacatcc cctaccagac
     1801 ctacatcgtg cccggcctgc tcggcatggt gctgctgttc aacggcatgc agtcctcgct
     1861 ggcgatggtg tacgaccgcg agatgggggt gatgcgcctg ctgctcaccg cgccgctgcc
     1921 gcgctggtac ctgctgctgt gcaagctgct cgccgggacc ttgctgtcgg tgctgcaggc
     1981 ctacgtcttc ctcgccgtgg cggcgctgtt cgacgtcggc gtgccgtggt cgggctggct
     2041 gtacgcgctg ccggtgctgg tgctggccgg catgatgctg ggcgcgctcg gcctcttgct
     2101 gtcggtgaac atccgccagc tggagaactt cgccggcacg atgaacttcg tcatcttccc
     2161 gatgttcttc ctgtcgcccg cgctctatcc gttgtggaag ctggaggagt cgggcgccac
     2221 cgtcatccac ttcctcgcca cctggaaccc cttcacccac gcggtcgagg ccatccgctt
     2281 cgcgctccac ggccaggtgg cggtgcactc gctggcgatc gtcgccggct gcctcgccgt
     2341 cttcttcctg ctcgccgcct ggggctacga cccgcagcgc ggcctgctgc ggcgcaccgg
     2401 caagccgggc tgagcgcccg gagcctggcg ctcggcgggg aaacgagcgg gccgcgggat
     2461 acaatccgcg gcccgttttt tcgtgctctc cgcccatgcc cgctccgtcc gccgctccgc
     2521 cgatcgattc cgacagcttc gcgctgctgg acgattgcca cgccaccgcg gccgcgccga
     2581 gcagccgtct ctacggcggc ctggtgcgcg tgcatcgctg cgcggacccg tccacgctgg
     2641 aggcgatgtg ggccgcggtg gacgccgacc tgcgcgccgg cctgcacgcc gtggtgctgg
     2701 ccgactatga atggggcgtg cggctgaacg gcgtcgtggc cgaggggccg gggccgggcg
     2761 cggggccggg ggcgggcggc agcctgcgcg tgctgatgtt cgccacgctg gcgcggcgct
     2821 cggccgcgga ggtggaggcc tggctggcgg aggccgaggc gcgggaggcg gagtcccccg
     2881 cggtggcgcc ggcgccggcc ggggcaggcg aggacgccag gcgcgccggc ccggcgcctg
     2941 ccggcgcgct cggcctgcgc gcctcggtcg atcgcgcggc cttcgaggag gcgatcgcgc
     3001 gcatccacgc cgcgatcgcc gagggcgaga cctaccaggt caactacagt taccgcctcg
     3061 atctcgagac cttcggctcg ccgctcgcgc tctaccgccg cctgcgcgcg cgccagccgg
     3121 tagcgttcgg cgccctgatc cgcctgcccg ccgaggccgg cgggccggac tgggtgctgt
     3181 cgtgctcgcc ggagctcttc ctgcgccacc acgacggcgt gctgcaggcg cgcccgatga
     3241 agggcaccgc cgcgcgcagc ggcgacgacg cggccgatgc gctcgccgcg cgccggctcg
     3301 ccgccgacgc caagaaccgc gccgagaacc tgatgatcgt cgacctgctg cgcaacgacc
     3361 tcggtcgcgt cgcgcgcacc ggcagcgtgc gcgtgcctgc gctgttcgag gtcgagcgct
     3421 acccgaccgt gctgcagatg acctcgacgg tcgcggcgga gctccccgcg gacgtcggct
     3481 ttcccgcgct gctgcgcgcg ctgtttccct gcggctcgat caccggcgcc cccaagcacc
     3541 gcacgatgca gctcatcacc gagctcgaga ccacgccgcg cggtctctac accggcagcc
     3601 tcggctggat cgacgcgccg cgcccggggc aggcctgcgg cgacttctgc ctgtcggtgg
     3661 cgatccgcac gctgacgctg gagcgcatcg aacagggcgc cgatgcgctc gccggtgcgc
     3721 ggcatcgcgg ccgcatgggc gtgggcgccg gcatcgtcat cgacagcgcg gccgccgacg
     3781 aatacgcgga gtgtcggctc aaggcgcgct tcctcagcgc gctcgacccc ggcttcgcgc
     3841 tcttcgagac gatgtacgcg acccgcgagg ccggcgtgcg ccagctcgac cgacacctcg
     3901 cccgcctcga agccagcgcc gccgcgctcg acttcgtgtt cgagcgcgca agcgtcgagg
     3961 ccgcgctcgg cggccagctc gccgcgctgc cgccggccac gccctcgcgc ctgcgcctgg
     4021 cgctgcacaa ggacggccgc ctcgagctca ccgccgccgc gctcgaggca ctgccgcccg
     4081 gcgcggtcac ggtgctgctc gccgagcgcc cgctcgacga cccgcacggc ctcggcgcgt
     4141 acaagaccac gctgcgtgcg cgctacgacg agggcctccg cgctgcgctg gccgcgggcg
     4201 ccttcgacac gctgttcttc gactcggcga gccgcctcac cgagggcggg cgcagcaacg
     4261 tcttcctgct cctcgatggc gagtggcgca ctccgcccgc cggccgcggg gtgctgcccg
     4321 gcacgatgcg cgccgcgctg ctggaggatc cggcgtgggc cgcgcgcgag gccgagctgc
     4381 gcgtggagga cctgctgcgc gcgcagcgca tcgtgctgac gaacgcgctg cgcggggcgg
     4441 tggaggcgag gctggcgggt gcgggcagca gggactgagc cgcccgcagg cacttacgcc
     4501 ggctgcgtgc gggatttgcg gcggcgcgtg gcggccaggc ccccaaggcc caggccgagc
     4561 aacgccagcg aggcaggttc gggcaccggg ttcggatcga cgatcacgcc gccctcctgc
     4621 tcgaagccgg cgtaacgtac ctgctcctgc gagttgttgt agaaaccgaa ttgccccgaa
     4681 gtgaaggcgc tgtcgctcac cgtggtgtcc cacaaggtgc ttgctccctg cttgaccacg
     4741 acgcggatca cgccgggcgt gaggttgaat tcgagcagga agtcgtagag ggcattgtcg
     4801 gcccagccgg cggtgcccga gtgattggtg gccagcacgc tcatgtcgcc gaagttgacc
     4861 tggttctccc agaactcttc cagcgacagg tcgttgagac cgtttccggt cgcacccgcg
     4921 aattttttga tcgtcatgcc ctccgccgcg gtccggccga cgtagccctg tgtgccctgt
     4981 ttccagtcga acaggtagaa gttgctggag ttctggtaac cgaacacgaa gcccatgtag
     5041 tcgtcgtcag agctggactg gacctgccag gatccctcca tcttgtaact ggtctggttc
     5101 aggttgttca gata
//
LOCUS       DAOTIN010000179         5029 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_19772_length_5029_cov_4.819662, whole genome shotgun sequence.
ACCESSION   DAOTIN010000179 DAOTIN010000000
VERSION     DAOTIN010000179.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 5029)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5029)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5029
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_19772_length_5029_cov_4.819662"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(2..685)
                     /locus_tag="P5537_16070"
     CDS             complement(2..685)
                     /locus_tag="P5537_16070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HRV79605.1"
                     /translation="MNGISLVGRRVLVTQAEDFMGPALCAAFAAAGAELIADRSAPRQ
                     PGSGRAVIESAGHIDALVLNLAIPAPSTPAHKVSDDEWEAAFAALVHPMREMVAAVLP
                     QMIERKAGKIVLMGSASALRGMARRSSYAAARGAQVAYIQAVGVEAAAHGIQVNAIAQ
                     NFVENPTYFPPEVQATQAFKDRLKWQVPLGRLVTAEEDAGFAVYLCSEAANCFVGQVF
                     PVCGGWVSR"
     gene            854..1498
                     /locus_tag="P5537_16075"
     CDS             854..1498
                     /locus_tag="P5537_16075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HRV79606.1"
                     /translation="MPRIEPFEAHAERYDAWFERHQASYVSELLALRAFVPVSGRGLE
                     IGVGGGRFAAPLGVEVGIDPSRTMLERARARGVEVFEGAAEHLPFADDSFDHALVVTT
                     LCFVDSPAAMLAEARRVLRPAGTLVIGFIDRDSPLGRDYEAHREASVFYRDATFYCAR
                     DVERLLLEVGFSVRSWAQTLARPLAETANIEPARPGRGECAFVVVAAMNDKPAR"
     gene            complement(1545..>1979)
                     /locus_tag="P5537_16080"
     CDS             complement(1545..>1979)
                     /locus_tag="P5537_16080"
                     /inference="COORDINATES: protein motif:HMM:NF013614.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HRV79607.1"
                     /translation="VRHTMRAEIRLMEEAVLHHQETHWHGEAGDIVVRPRAQVRLERG
                     ARYLADFSLLHGRVGQINVDYAVTVGEGAVTELTSRIYGFANDAIRVCERVVLDGAGA
                     RGLVKSRVAVRDEISGVAVPPSRRSDGWSRSPARSPQPPRGW"
     assembly_gap    1980..2079
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(2170..2913)
                     /locus_tag="P5537_16085"
     CDS             complement(2170..2913)
                     /locus_tag="P5537_16085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV79608.1"
                     /translation="MADPVLHLEGLRKRYGSADTEYEVLHGIDLRLERGEFAALIGPS
                     GSGKSTLLNLIGLLDRPSAGRLVIDGAETATLDDTALTRLRGERIGFVFQHHHLIPAF
                     SAEENVAMPLLIARGRPDAAMFERAGELLGRVGLADRRRQLANRLSGGQQQRVAIARA
                     LAMSPALVLADEPTGNLDTHSADEVFALLREVNRQLGTSFLIVTHDPRLAHRCDRIIE
                     LVDGRIVSDRPNEVAAGRCPAEGSAEETE"
     gene            complement(2906..4126)
                     /locus_tag="P5537_16090"
     CDS             complement(2906..4126)
                     /locus_tag="P5537_16090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV79609.1"
                     /translation="MKSWMPFEWIAALRFLQEGRMQSLLIIVGVGVGVAVIVFMSALL
                     SGLQANLVRRTLSSQAHVVLLPAEEVARPQAAGEGVAARVQKQAQRLRSIDQWQQLRA
                     RLEGWPEIAAVSPVASGPAFAVRGDASKAVTLLGIEPARYNRVVDLAGRLAAGALRVG
                     AGETVIGIELAKDLGAEVGDKLRLTGAEGQAETLTVTGLFDLGNKGVNARNVYVGLRT
                     GQTLLDLVGGVSNIDLALHDLDEAEDVAQRIAAESGLIADSWIRTNAQFVTALTSQRV
                     SSDVIRFFIALSVSFGIASVLVVSVVQRSKEIGILRAMGATQAQMRRIFLLQGGIVGF
                     LGSLLGSALAWSFLMLWRMLARNPDGTPLFDIGVEPALVAIAAGGASVVGILAALLPA
                     RRAARLDPVVAIRG"
     gene            complement(4123..>5029)
                     /locus_tag="P5537_16095"
     CDS             complement(4123..>5029)
                     /locus_tag="P5537_16095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HRV79610.1"
                     /translation="SAAVTQAEARLRQLRELGLPVAEQALRQAEATALQARQQHRRVR
                     ELVARGFYSQAQLDEARRVQEVAESQVASARLQRDSQQPDGIEVALAQSALEQARAAL
                     VAAQTRLGYAILRAPSAGTVLTRAVEAGDTVQPGAVLLTIAPAGDTELTVQIDEKNLG
                     LLRLGQPALASADAYPGERFAAELAFIAPSVDALRGSVEVRLRVPEPPPYLRHEMTVS
                     IDIEAARREQTLMIPAAAVRETGGAQPWVMVVRDGRTERQPVRLGIRGAGRVEVLEGV
                     AVGEALVPAAVDVAAGQAVRTRAAP"
BASE COUNT          727 a         1799 c         1700 g          703 t
ORIGIN      
        1 ctcaccggct cacccacccc ccgcacaccg gaaagacctg ccccacgaag cagttcgcgg
       61 cctcgctgca cagatagacg gcaaagcccg cgtcctcttc agccgtgacc agccgaccca
      121 gcggcacctg ccacttcaag cgatccttga acgcctgcgt ggcctggacc tcgggcggga
      181 agtaggtggg gttctccacg aagttctgcg cgatggcatt cacctggatg ccgtgcgcgg
      241 cagcctcgac ccccacggcc tggatgtagg ccacctgcgc gccacgcgcg gcggcgtagc
      301 tcgagcgccg agccatgccg cgcagcgcgg aggcgctgcc catcagcaca atcttgcccg
      361 ccttgcgctc gatcatctgc ggcaggacgg cggcgaccat ctcgcgcatg ggatggacca
      421 gggcggcgaa ggcggcctcc cactcgtcgt ccgacacctt atgggcgggc gtgctcggcg
      481 ccgggatggc caggttgagg acgagggcgt cgatgtggcc ggcagactcg atgacggcgc
      541 gcccgctccc cggctgccgc ggcgcgctgc gatccgcgat gagctcggcg cccgccgcgg
      601 cgaaggccgc gcacagcgcc ggccccatga agtcttcggc ttgggtgacc agcaccctgc
      661 ggccgaccaa tgaaatcccg ttcatttcgc ttctcctcca cggcagcgcg agcctgctcc
      721 cggcccctgg attcaatcct aggacgaaga cgtctagact gcacccgccg ggatcgatcc
      781 ggtgcaggcg gcaaggcgcc tgcccctgca aacgccggcc actttttcac cactccggac
      841 gaggttctgc aagatgccaa ggatcgagcc tttcgaggcg cacgcggaac gctacgacgc
      901 ctggttcgaa cgccaccagg ccagctatgt ctccgagctg ctggccttgc gagccttcgt
      961 cccggtgagc gggcgcggcc tggagatcgg cgtcggcggc ggacgcttcg ccgcgccgct
     1021 gggggtggag gtggggatcg acccgtcgcg gacgatgctg gagcgggcgc gggcgcgcgg
     1081 ggtcgaggtc ttcgagggcg ccgccgagca tctgcctttc gccgacgaca gcttcgatca
     1141 cgcgctcgtc gtcaccacct tgtgcttcgt cgactcgccc gcggcgatgc tggccgaggc
     1201 gcggcgggtc ctgcggccgg ccggcaccct ggtgatcggc ttcatcgacc gcgacagtcc
     1261 gctcggccgc gactacgagg cgcaccgcga ggccagcgtc ttctaccgtg acgccacctt
     1321 ctactgcgcg cgcgacgtcg agcgcttgct gctggaggtc ggattttccg tgcggtcgtg
     1381 ggcgcagacg ctggcccgtc cactcgccga gaccgcgaac atcgagccgg cgcgccctgg
     1441 tcgaggcgag tgcgccttcg tggtcgtcgc ggccatgaac gacaagcctg cacgctgaac
     1501 acggcgcaaa acccgcatgc agaccacttt ctggaccgcc ctgctcacca gcctcgcggc
     1561 ggctgcggtg acctcgctgg ggatctggac catccgtcgc ttcgccgact ggggggcacc
     1621 gcaacaccgc ttatttcgtc gcgtaccgcc acgcgtgact tgacgaggcc gcgagccccg
     1681 gcgccatcga gcacgacgcg ctcgcacacg cggatggcgt cgttggcaaa gccatagata
     1741 cggctcgtga gttcggtgac cgcgccctcg ccgaccgtga ccgcgtagtc gacgttgatc
     1801 tgcccgacac gaccatgcag caggctgaag tccgccaggt agcgcgcacc gcgttccaga
     1861 cgcacctgcg cgcggggacg aacgacgatg tccccggcct cgccatgcca gtgcgtctcc
     1921 tggtggtgca gcacggcctc ttccatcagc cggatctcgg cacgcatggt gtggcgaacn
     1981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnc cagccggctt cgccgaaaag
     2101 tcgggtgatg ggatgcaggt cagtcattgc aggtcggcgc gccgacagcg gaatttgcag
     2161 acgtgtcgtt cattcggttt cctctgcact gccctcagcc gggcaccggc cagcggctac
     2221 ttcgttgggc cggtcggaga cgatgcgacc gtcgaccagc tcgatgatgc ggtcgcagcg
     2281 gtgagcaagg cgcgggtcgt gggtgacgat caggaagctg gttcccagtt gccgattgac
     2341 ctcgcgcagc agcgcgaaga cctcgtccgc cgagtgcgtg tcgaggttgc cggtgggctc
     2401 gtcggcgagc acgagcgccg gcgacatcgc cagcgcacgg gcgatggcga cgcgctgctg
     2461 ctggccgccg gacaagcggt tggcaagctg gcgccgccgg tccgccaggc cgacacgccc
     2521 gagcagctct ccggcgcgct cgaacatcgc cgcgtccggc cgcccgcgtg cgatcagcag
     2581 cggcatggcc acgttctcct cggcgctgaa ggccgggatc aggtggtggt gctggaacac
     2641 gaagccgatg cgctcgccgc gcaggcgggt gagcgcggtg tcgtcgagcg tcgccgtctc
     2701 ggcgccgtcg atgacgagcc gcccggcgct cgggcggtcg agcaggccga tgaggttgag
     2761 cagcgtgctc ttgccggagc ccgaggggcc gatgagggcg gcgaactcgc cacgctcgag
     2821 gcgcaggtcg atgccgtgca gcacctcgta ttcggtgtcg gcgctgccgt agcgcttgcg
     2881 caatccttcg aggtgcagga cgggatcagc cacggatcgc caccaccggg tccagtctcg
     2941 ccgcgcgccg cgccggcaac agggcggcga gaatgccgac cacgcttgca ccgcccgcgg
     3001 cgatcgcgac cagcgccggc tcgacgccga tatcgaacag cggcgtgccg tcggggttgc
     3061 gcgcgagcat ccgccacagc atcaggaagg accacgccag cgccgagccc agcagggatc
     3121 cgaggaagcc cacgatgccg ccttgcagca ggaagatgcg ccgcatctgc gcctgcgtcg
     3181 cccccatcgc acgcaggatg ccgatttcct tgctgcgctg gaccaccgac accaccagca
     3241 cgctggcgat gccgaaggac accgacagcg cgatgaagaa gcggatcacg tcgctcgaca
     3301 cccgctgcga ggtgagcgcg gtgacgaact gcgcgttggt gcggatccag ctgtcggcga
     3361 tcaggccgga ctctgcggcg atgcgctgcg cgacgtcctc ggcctcgtcg aggtcgtgca
     3421 gcgcgaggtc gatgttcgac acgccaccga cgaggtcgag cagggtctgc ccggtgcgca
     3481 agccgacgta gacgttgcgc gcattgacac ccttgttgcc gaggtcgaag agcccggtga
     3541 cggtcagcgt ctcggcctgg ccctcggcgc cggtgaggcg cagcttgtcg ccgacctccg
     3601 cgccgaggtc cttggccaac tcgatgccga tcaccgtctc gcccgcgccg acgcgcagcg
     3661 cgccggcggc gaggcgcccc gccaggtcca cgacgcggtt gtagcgcgcg ggctcgatgc
     3721 cgagcagcgt caccgccttg ctggcgtcac cgcgcaccgc gaaggcaggg ccggaggcca
     3781 ccggcgacac cgcggcgatc tcgggccacc cttccaggcg cgcgcgcaac tgctgccact
     3841 ggtcgatcga gcgcagccgc tgcgcctgct tctgcacgcg ggccgcgacg ccttcccctg
     3901 cagcctgcgg gcgcgccacc tcctctgccg gcagcagcac gacgtgcgcc tgcgagctca
     3961 gggttcggcg caccaggttg gcctgcaggc cggacagcag cgcggacatg aacacgatca
     4021 ccgccacgcc gaccccgacg ccgacgatga tcagcagcga ctgcatccgc ccctcctgca
     4081 ggaagcgcag cgcggcaatc cactcgaagg gcatccagga cttcatggcg cagcccgtgt
     4141 ccgcaccgcc tgcccagccg ccacatccac ggccgccggc accagcgctt ccccgacggc
     4201 gaccccctcg agcacctcga ccctgcccgc accgcggata ccgagccgca ctggctgacg
     4261 ctcggtgcgg ccatcgcgca ccaccatcac ccagggctgc gcgccgccgg tctcgcgcac
     4321 cgctgccgcg ggaatcatca gcgtctgctc gcgacgcgca gcctcgatgt cgatcgagac
     4381 cgtcatctcg tggcgcaggt agggcggcgg ctcggggacg cgcaggcgca cctcgaccga
     4441 gccgcgcagc gcatcgaccg agggcgcgat gaaggcgagc tccgcggcga agcgctcgcc
     4501 cggataggcg tccgccgagg ccagggcggg ctggcccagg cgcagcaggc cgaggttctt
     4561 ctcgtcgatc tgcacggtga gctcggtgtc gcccgcgggg gcgatcgtca gcagcacggc
     4621 gccgggctgc acggtgtcgc ccgcctcgac cgcgcgcgtg agcaccgtgc ccgcggacgg
     4681 cgcacgcagg atcgcgtagc cgagccgggt ctgcgcagcg accagcgccg cgcgcgcctg
     4741 ttcgagcgca ctctgcgcca gcgccacctc gatgccatcg ggctgctggc tgtcgcgttg
     4801 caggcgggcg ctggcgacct ggctctcggc cacctcctgc acgcgtcgcg cctcgtcgag
     4861 ctgcgcctgg ctgtagaagc cgcgcgccac cagttcgcgc acgcgccgat gctgctggcg
     4921 tgcctgcagc gcggtggcct cggcctggcg cagcgcctgc tcggcgaccg gcaggccgag
     4981 ctcgcgcagc tggcgaagac gcgcttccgc ctgcgtcacc gcggcgctc
//
LOCUS       DAOTIN010000180         5023 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_19812_length_5023_cov_9.539855, whole genome shotgun sequence.
ACCESSION   DAOTIN010000180 DAOTIN010000000
VERSION     DAOTIN010000180.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 5023)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5023)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5023
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_19812_length_5023_cov_9.539855"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..638
                     /locus_tag="P5537_16100"
     CDS             <1..638
                     /locus_tag="P5537_16100"
                     /inference="COORDINATES: protein motif:HMM:NF025684.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4384 domain-containing protein"
                     /protein_id="HRV79611.1"
                     /translation="TVREAPAPVAADRATPAPPALPEPPSPAAFPPAVAPYSPLAEIE
                     RIHRERDPLRSVGIGLANPQVRIGIDRLSFRVRSSAAGYLYVLMLGTDGHFYKLFPNA
                     IDRDNRVRAGASIELPRSGWRMTAGGPPGTNHLIAVVSERPRDFTASGLVEVDPFAEF
                     PPERAAQVAAGHRGSQSPFIGTPSCPDAGQPCSDAYGAASFTIVEVAPDRR"
     gene            complement(711..1247)
                     /locus_tag="P5537_16105"
     CDS             complement(711..1247)
                     /locus_tag="P5537_16105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004373798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015288 - porin activity [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HRV79612.1"
                     /translation="MKMRFPTRSGVVLTIAAMLAPVALAQPVLRGSEITEDRLIDALT
                     PGPDEVRTRSIRVEREAPTAKKGAASLLITFETNSARLSSAAERSLDVVARALQADRL
                     AAFNFSVEGHADPRGGADYNLRLSQARAESVVDYLAGRHGIPRDRLRPIGKGQTELAN
                     PGRPTAPENRRVTIKTLQ"
     gene            complement(1274..2044)
                     /locus_tag="P5537_16110"
     CDS             complement(1274..2044)
                     /locus_tag="P5537_16110"
                     /inference="COORDINATES: protein motif:HMM:NF018884.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein phosphatase"
                     /protein_id="HRV79613.1"
                     /translation="MKLDIAVLSRTGGRPTNEDACGYWTSDAAACWVLADGAGGHGAG
                     DVAARCVVASVLRGFASAPDSTPAALSQLIAQANADLLGAQHEARGQRDMRSTVTVLA
                     VDRSGWRASWAHVGDSRVYAFRGGRLRLQSRDHSVVQDLIDAGLGDPSMLRKHPQRSV
                     LLAALGSAEAPRPELSAQPERVVDGDVYMLCSDGLWEYVEEAEMEDSLRRSESAQGWL
                     DALERGVLSRARHGHDNYSAIAVWIGDPAEVTRFAARS"
     gene            complement(2041..4140)
                     /gene="tagH"
                     /locus_tag="P5537_16115"
     CDS             complement(2041..4140)
                     /gene="tagH"
                     /locus_tag="P5537_16115"
                     /inference="COORDINATES: protein motif:HMM:TIGR03354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system-associated FHA domain
                     protein TagH"
                     /protein_id="HRV79614.1"
                     /translation="MTPELHPQSRAGHFAFITSVSWKEPFLLSMMKSWLPRLACWGTA
                     AFFGHGGGLVQMIRIRVLSIDGSAPAQPSQAEFAEAGGTIGRAESNDLVLDDPDRHVS
                     RVQARVECGTAGCRLTNLGTNPVDVDGRGLSTGEAAALRAGVRIVIGRYVLEALDLRE
                     AASSSPGPAMAAPAPGGEAIGVAGDPLGLFGAGIGQARADDPFAEFLSPSPSAPTVPP
                     SAAGNSPAPPGGVTNAAVGAVDASRGRATGARPLIPDDFDPFAEPMEPPPAARPSPPP
                     ALDELGFGARGPETGEAGISTMFGLGPTERDAALDPFAGTPLAEPAAAPSAGAEGAPA
                     VPLDPLDAMFDAPAKPAPAAPLPDHVPELDGSFRPPAAAPNAPQDAFLSWDAERSPAV
                     SSGAPAARQQGEAQFRDADAAMAPVGEPAATSGTGAGAPQPPQGAPPPPAGVHLEALG
                     GMGPSVPDAQDLSGAPAVVAAPARAGIVPSTPSTASAPRSDESAALMRAFLSGLDISD
                     PGLPAQPSPEWMQAIGRLLREATQGTLDLLLARAVVKREVRAEVTMIVSRGNNPLKFS
                     PNVEVALSHLLAPRGQGFLSPVEAMRDAYGDLRAHEFGFMAGMRAALAGVLARFDPQA
                     LEARLSEPSMLDNLVPINRRARLWGLYTELYREIAREAEDDFQDLFGKAFLHAYEEQV
                     RRMEAGEKDEDGETAGS"
     gene            4275..4778
                     /locus_tag="P5537_16120"
     CDS             4275..4778
                     /locus_tag="P5537_16120"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79615.1"
                     /translation="MYYKNMGADLGFNILEQTLTGEIDGVSISAHAVSGGRAGSKTPG
                     AENPILANNPYLTSVKKQGKRAGGPLIMGLYTLRTHEKRANWIRLIPYADNRMRDRAG
                     FAIHGRGARGSDGCIVPTDFNVVKLLHSLVASREASGAAAPILAVYAVGDFDVLDRRL
                     AEWSSTA"
BASE COUNT          762 a         1844 c         1700 g          717 t
ORIGIN      
        1 ccaccgtacg cgaagcaccc gcgcccgttg ccgccgatcg tgcgactcct gcgccgcccg
       61 ccctccccga gccgccctca cccgctgcct tcccgccggc cgtggcgccc tattcgccgc
      121 tcgccgagat cgagcggatc caccgcgagc gcgacccgct gcgcagcgtc ggcatcggcc
      181 tcgccaatcc gcaggtccgc atcggcatcg accgcctgag ctttcgcgtg cgctccagcg
      241 cggcgggcta cctgtacgtg ttgatgctcg gcaccgacgg ccacttctac aagctcttcc
      301 cgaacgcgat cgaccgcgac aaccgcgtgc gcgcgggcgc ctcgatcgaa ctgccacgca
      361 gcggctggcg catgacggcc ggcggtccgc cgggcaccaa ccacctgatc gcggtggtca
      421 gcgagcggcc gcgcgacttc actgcgagcg gcctggtcga ggtcgatccc ttcgccgagt
      481 ttccgcccga gcgcgcagca caggtggcgg cgggccatcg cgggagccag tctcccttca
      541 tcggcacgcc ctcctgtccc gatgccggcc agccctgctc cgacgcctac ggcgcggcca
      601 gcttcacgat cgtcgaggtt gcccccgacc gtcgctgagt gcgcacccgc ctcccggccg
      661 gggatcgact ccccggccac cgaccgtccc agcccctttc gagcgccgca tcactgcagc
      721 gtcttgatgg tcacccgacg gttctcgggc gcggtggggc gaccggggtt ggcgagctcg
      781 gtctggccct tgccgatcgg gcgcaggcgg tcgcgcggga tgccgtggcg cccggcgagg
      841 taatcgacca cgctctcggc gcgggcctgc gacaggcgca ggttgtaatc agcgccgccg
      901 cgcggatcgg cgtgcccctc gaccgagaag ttgaaggcgg cgaggcggtc ggcctggagc
      961 gcgcgcgcca cgacatcgag cgagcgctcg gccgccgagc tcaaacgcgc cgagttggtc
     1021 tcgaaggtga tcagcaacga ggccgccccc ttcttcgcgg tcggcgcctc gcgctctaca
     1081 cggatgctgc gcgtacgcac ctcgtcgggt ccgggcgtca aggcatcgat caggcggtct
     1141 tcggtgatct cgctgccgcg cagcaccggc tgcgcgaggg ccacgggtgc gagcatcgcc
     1201 gcaatcgtga ggacgacgcc cgagcgggtg gggaaacgca tcttcatgat ctctctcctg
     1261 tgttgttgtc ggttcagctt cgtgccgcga agcgggtcac ctcggcagga tctccgatcc
     1321 agaccgcgat cgcgctgtag ttgtcgtggc cgtggcgcgc gcggctcagc accccgcgct
     1381 cgagcgcatc gagccagccc tgcgccgatt cgctgcgccg caggctgtct tccatctcgg
     1441 cctcctcgac gtattcccac aagccgtcgc tgcacagcat atagacgtcg ccgtcgacca
     1501 cgcgctcggg ctgcgcggac aactccgggc gcggcgcttc ggcgctgccc agcgcggcca
     1561 gcagcacgct gcgctgcgga tgcttgcgca gcatcgaggg gtcgccgagc cccgcgtcga
     1621 tcagatcctg caccacgcta tggtcgcgcg actgcaggcg caggcgcccg ccgcgaaacg
     1681 catacacgcg cgaatccccg acgtgcgccc aactcgcccg ccagccgctg cgatccaccg
     1741 cgagcacggt cacggtcgat cgcatgtcgc gctggcccct ggcctcgtgc tgggcgccga
     1801 gcaggtcggc gttggcctgc gcgatgagct gcgacagcgc cgccggcgtg ctgtcgggcg
     1861 ccgaggcgaa gccgcgcagc accgaggcga ccacgcagcg cgcggccaca tcgcccgcgc
     1921 cgtgtccgcc cgccccgtcg gccagcaccc agcaggccgc cgcatccgag gtccagtagc
     1981 cgcaggcatc ctcgttggtc gggcgccccc cggtgcgcga caacaccgcg atatcgagct
     2041 tcatgatccg gccgtctccc cgtcctcatc cttctcgccg gcctccatgc gtcgcacctg
     2101 ctcctcgtag gcgtgcagga aggcctttcc gaagagatcc tggaagtcgt cctccgcctc
     2161 gcgcgcgatc tcgcgataga gctcggtgta caggccccac aggcgcgcac ggcgattgat
     2221 cggaaccagg ttgtcgagca tggaaggctc gctcagccgg gcctcgagcg cctgcggatc
     2281 gaagcgcgcc agcacccccg cgagcgccgc ccgcatcccg gccatgaagc cgaactcgtg
     2341 cgcgcgcaga tccccgtagg cgtcgcgcat cgcctcgacc ggagacagga agccctgccc
     2401 gcgcggcgcg agcaggtgag acagcgcaac ctcgacgttg ggcgagaact tgagcggatt
     2461 gttgccgcgg ctgacgatca tggtcacctc ggcgcgcacc tcgcgcttga ccaccgcgcg
     2521 cgccagcagc aggtccaggg tgccctgcgt agcctcgcgc agcaggcggc cgatggcctg
     2581 catccactcc gggctgggct gcgccggcag ccccgggtcg gagatgtcca gaccggaaag
     2641 gaaggctcgc atcaacgcgg cggactcgtc gctgcggggc gcgctggccg tggacggcgt
     2701 ggagggcacg atccccgccc gtgcgggggc tgccacgacc gcgggcgcgc cactcaagtc
     2761 ctgcgcatcc ggcaccgacg gccccatccc gcccaatgct tcgaggtgca cgccagccgg
     2821 cgggggcggc gcaccctgcg gcggttgcgg cgcacccgca cctgtgcccg aagtcgctgc
     2881 cggctcgccc accggcgcca tcgccgcatc ggcgtcgcga aactgcgctt cgccctgctg
     2941 ccgcgctgcc ggtgcgccgg atgaaacagc cggagatcgt tcggcatccc aggaaaggaa
     3001 ggcgtcctgc ggggcattcg gagccgcggc cggcggccgg aaactgccgt cgagttcggg
     3061 cacatggtcc ggcagaggcg cggccggtgc tggcttcgcc ggtgcgtcga acatcgcgtc
     3121 gagcggatcg agcggcaccg cgggcgcacc ctctgccccg gcggacggtg cggccgcggg
     3181 ttcggcgagc ggagtccccg caaaaggatc gagcgccgcg tcgcgctccg tcggcccgag
     3241 cccgaacatc gtgctgatgc ccgcctcccc ggtctccggg ccgcgcgcgc cgaaaccgag
     3301 ctcgtccagc gcgggcggcg ggctcggacg cgctgcgggc ggcggctcca tcggctcggc
     3361 gaagggatcg aagtcgtcgg ggatcagcgg gcgagcgccc gtcgcgcggc cccgcgaggc
     3421 atcgacagcc ccgacagcgg cgttcgtcac cccgccgggt ggagccgggg agttccccgc
     3481 tgcgctcggc ggcacagtcg gcgcactcgg tgaaggcgag aggaattcgg cgaacgggtc
     3541 gtccgcccga gcttggccga tccccgcacc gaacaggccg agcggatccc cggccacgcc
     3601 gatcgcctcg ccgcctggcg cgggggctgc catggccgga cccggggaag aggacgccgc
     3661 ctcgcgcagg tcgagcgctt cgagcacata gcggccgatc acgatgcgca ccccggctcg
     3721 cagcgcagcc gcctccccag tactcaggcc gcgcccgtcg acatcgaccg gattggtgcc
     3781 gaggttggtg agccggcaac ccgccgtacc gcactccacc cgagcctgca cgcgcgagac
     3841 gtgacgatcg ggatcgtcca gcacgaggtc attgctctcg gccctcccga tggtgcctcc
     3901 ggcctcggcg aattcggcct gcgaaggctg ggccggcgcc gagccatcga tggaaagtac
     3961 gcggatccgg atcatctgca cgagccctcc cccatgcccg aaaaaagccg ccgtgcccca
     4021 gcacgcgagc cggggcagcc acgatttcat catagacagc aggaagggct ccttccatga
     4081 aaccgaagtg atgaaggcga agtgcccggc gcgggactgc ggatggagtt cgggcgtcat
     4141 gcagtgctgc cgacctcgcg gaagacgcgg cgcggtgcta tgaagaaact gtccgcgata
     4201 tgcagcgccg cgcttgcatc gccggccttg gcggcgccca gcagcacttg ccgttttcca
     4261 gggaggaacg ggagatgtat tacaagaaca tgggtgccga tctcggcttc aatatcctcg
     4321 agcagacgct caccggcgaa atcgacggtg tttcgatcag cgcacacgcg gtttccggcg
     4381 gacgcgccgg cagcaagacc ccgggcgcag agaatccgat tctcgccaac aatccctatc
     4441 tcacctcggt gaagaagcag ggcaagcgtg ccggcgggcc gctgatcatg ggtctgtaca
     4501 ccctgcgcac ccatgagaaa cgggcgaact ggatccgcct gatcccctat gcagacaacc
     4561 ggatgcgcga ccgcgcggga tttgcgatcc acggtcgcgg agcgcgcggg agcgacggtt
     4621 gcatcgtacc caccgacttc aacgtggtga aactgctcca ctccctcgtc gccagccgtg
     4681 aggcgtccgg ggcggcagcg ccaatcctcg cggtgtacgc cgttggggat ttcgatgtcc
     4741 tcgatcgacg ccttgcagaa tggtcgtcga cggcctgagg cgggatgcgt attcgataca
     4801 gggcgaattc ccgaggcagg agccacggcc acgagggatt ccctcggccg accggtcgtg
     4861 agtcaggcct ggacccgaag cagcgggtcc tgcttggcaa gcgacccggc aggatcctcg
     4921 cctccgctct ccttcacatt tctcgtcgag caaaaaatga gcaatcagcc aagccgcgcc
     4981 atcgtggtcg ccgaggccct gtccatcggc aggaaggact aca
//
LOCUS       DAOTIN010000181         4903 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_20488_length_4903_cov_6.941419, whole genome shotgun sequence.
ACCESSION   DAOTIN010000181 DAOTIN010000000
VERSION     DAOTIN010000181.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 4903)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4903)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4903
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_20488_length_4903_cov_6.941419"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(177..776)
                     /locus_tag="P5537_16125"
     CDS             complement(177..776)
                     /locus_tag="P5537_16125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004360909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxychromene-2-carboxylate isomerase"
                     /protein_id="HRV79616.1"
                     /translation="MSRPVVEFWFEFASTYSYLSVMRIERAAEAAGVDIEWKPFLLGP
                     VFLALGWNDSPFNIYPPKGRYMWRDLERLAEKEGLPFLRPSRFPRNGLLAARVALVGV
                     EEGWVAAFARAVMMANFAEDREIGEEAVIGAILGTLGLPAAEVIARAQADANKLALRC
                     QTERAAELGLFGAPSFRVGEELFWGNDRLEDALAWARRA"
     gene            complement(892..1773)
                     /locus_tag="P5537_16130"
     CDS             complement(892..1773)
                     /locus_tag="P5537_16130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004328264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HRV79617.1"
                     /translation="MHKTELDRLAIGLMVVLCSIWGLQQVAIKLASAGISPVWQAGLR
                     SLGATVIVVAWALLRGVKLFERDRSLAPGLLAGALFAGEFAMIFLGLQHTSASRGVIF
                     LYTAPFFVALGAVRLLPQEHMRRRQWMGMALAFVGVLALFGENLFSAAEGAWVGDLML
                     LGAAVLWAATTLTVKASALARASAEKTLLYQLGVSALVLPPLSLAMGEPGVFAPTPMV
                     WANLFFQAAIVAGVSYLAWFWLVREYPATRLSSFSFLTPVMGVLAGGLILGEPLTPAV
                     FAALFLVGSGIWVANRS"
     gene            complement(1824..2711)
                     /locus_tag="P5537_16135"
     CDS             complement(1824..2711)
                     /locus_tag="P5537_16135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004378515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6279 family lipoprotein"
                     /protein_id="HRV79618.1"
                     /translation="MPARPLRRLILIACSALLLAGCGLRFAYSQLDWLLPWYLRDYVT
                     LNAGQRSELDVRLAGLLDWHCRSHLPEYVALLRAANTTLASERVEAAQLEPFLERGEA
                     LWREIVAELEPELRALLAGLSDEQVEELAASFARRGEEARAEFLSGDAAAQHAARVER
                     MEERLRRWFGRMTPAQRERIAAWSRALQPTTEAWLEDRARWQDELLDALRVRADAVAF
                     TPRLALVLAPRETRWTAQHRAAVAHNRARTLELLADLHALSGEAQRRRLQGEIDALAS
                     QFAGMACTEPARVSAAGGR"
     gene            complement(2769..3479)
                     /locus_tag="P5537_16140"
     CDS             complement(2769..3479)
                     /locus_tag="P5537_16140"
                     /inference="COORDINATES: protein motif:HMM:NF018049.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1043 family protein"
                     /protein_id="HRV79619.1"
                     /translation="MTPQTAWLLAISAVVIVGVIAFFVGRSSAGTKGRIDELEAELAR
                     KSEEAERYRKEVDAHFDKTATLFVSMAGSYKELFEHLSAGYDKLSGASARERFQERVD
                     ALLPRRVVEPAASGALLAGAATAAAAASPDAGAEVEPAVETVAEVVPATVADAAPALA
                     AEAEVLPEPAQASVAATAEAPAVEHEAAATAPAAFGAVEPETEAADADAAERVRRAEG
                     AAEAAAAESSAEPRAEAR"
     gene            complement(3510..4544)
                     /locus_tag="P5537_16145"
     CDS             complement(3510..4544)
                     /locus_tag="P5537_16145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HRV79620.1"
                     /translation="MADALRVLALVACALLLAACSRAQVFHHEAYVFGTRVDVAVYGE
                     NQAEADRAAAAVLREFDRLHRAYHAWEPSELTALNAAIARGEAATVSDELAAMLKDAQ
                     AIAATGDGLFDPALGGLVALWGFHSDSFVPQRPDPDRLQALLAARPSMADLVIDGNRV
                     ESGNRAVQLDLGGYAKGYALDRAAAILREAGTVNALINIGGNVMALGGKGDQPWRIGI
                     QHPRAPAPLATLPLYDGEAIGTSGDYQRYFELDGERYAHLLDPRTGQPAHGTQSLTVL
                     VTARAKAGTLSDAPSKPAYLAGDGWREQIRRFGIEHALRVAADGRIEVTRELRARLQF
                     PSPVEATVVD"
     gene            complement(4586..>4903)
                     /locus_tag="P5537_16150"
     CDS             complement(4586..>4903)
                     /locus_tag="P5537_16150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione synthase"
                     /protein_id="HRV79621.1"
                     /translation="RVLIIGGEVVPFALARIPRAGETRGNLAAGGRGVAMALTARERE
                     IAEFLAPTLWARGLLIVGLDVIGGHLTEINVTSPTCMVEIATQQGFDVAGLVIDKLER
                     ACG"
BASE COUNT          720 a         1779 c         1804 g          600 t
ORIGIN      
        1 cccgcaccaa gcggcctcga tcccgtcacc acccgcacgg cctcgttcgc ggctgccgcc
       61 gctcctacag gcgcccccgg aagcgcgatg gttcatgtag gagcgccggc aggcgcgaac
      121 gaggccgcgg ccccgccgcc gcgcccggcc aatgcgcgaa tacggcggac gaccgatcag
      181 gcgcggcggg cccaggcgag tgcgtcttcc aggcggtcgt tgccccagaa cagttcctcg
      241 ccgacgcgga agctcggcgc gccgaagagg ccaagctcgg ccgcgcgctc ggtctgacag
      301 cgcagcgcga gcttgttggc gtcggcctgt gcgcgtgcaa tcacttccgc ggcaggcagg
      361 ccgagcgtgc cgaggatcgc gccgatcacc gcctcctcgc cgatctcgcg gtcctcggcg
      421 aagttcgcca tcatcaccgc gcgcgcgaag gccgccaccc agccctcctc cacccccacc
      481 agcgccaccc gcgcggcgag cagcccgttg cgcgggaaac ggctcggacg gaggaagggc
      541 aggccctcct tctccgccag gcgctcgagg tcgcgccaca tgtagcgccc cttgggcggg
      601 tagatgttga agggcgaatc gttccagccc agggcgagga agaccggccc gagcaggaag
      661 ggcttccatt cgatgtccac gccggcagcc tccgcggcgc gttcgatgcg catcaccgac
      721 aggtaggaat aggtgctggc gaactcgaac cagaactcca cgacaggtcg ggacatgagg
      781 cgctcctcgg aagacggtgg atgccgtcac tataggccat cgcccccctg cacgccccgc
      841 gatggggcgc cgcctgcagg cgcacgccag cgcccgcgct gccccctcgc gctaggagcg
      901 gttcgccacc cagatcccgc tgccgacgag gaagagggcg gcgaacaccg ccggcgtcag
      961 cggctcgccg aggatcagcc cgccggcgag cacgcccatc accggagtca ggaaggagaa
     1021 cgaggacagg cgcgtggccg gatactcgcg caccagccag aaccaggcga ggtaggacac
     1081 gccggcgacg atcgcggcct ggaagaacag gttggcccac accatgggcg tgggcgcgaa
     1141 cacgcccggc tcgcccatcg ccagcgagag cggcggcagc accagcgccg acacgccgag
     1201 ctggtagagc aaggtcttct cggccgatgc acgcgccagc gcgctcgcct tcaccgtcag
     1261 cgtggtcgcc gcccacagca ccgcggctcc gagcagcatc aggtcgccca cccaggcgcc
     1321 ctcggccgca gagaagaggt tctcgccgaa gagcgcgagc acgccgacga aggcgagcgc
     1381 catgcccatc cactgccggc gtcgcatgtg ctcctgcggc agcagccgga ccgcgccgag
     1441 ggcgacgaag aagggcgcgg tgtacaggaa gatcaccccg cgcgaggcgc tggtgtgctg
     1501 caggccgagg aagatcatcg cgaactcgcc ggcgaacagc gcgcccgcga gcaggccggg
     1561 cgcgaggctg cggtcgcgct cgaagagctt caccccgcgc agcagcgccc aggcgacgac
     1621 gatcaccgtg gcgccgagcg agcgcaggcc cgcctgccat accggcgaga tgccggcgct
     1681 ggcgagcttg atggcgacct gctggaggcc ccagatcgag cacagcacca ccatgaggcc
     1741 gatggcgagg cgatcgagtt cggtcttgtg catgcggggg agccggcgcg ggagcgcggg
     1801 cgggtgggag gcgaagggcg cgattatcgg ccgccggcgg cggaaacgcg agccggttcg
     1861 gtgcaggcca tgcccgcgaa ctggctggcg agcgcgtcga tctcgccctg caggcggcgg
     1921 cgctgggcct cgccggacag cgcatgcagg tcggcgagca gctccagcgt gcgcgcgcgg
     1981 ttgtgcgcga ccgccgcacg gtgctgcgca gtccagcgcg tctcgcgcgg cgccagcacc
     2041 aacgccaggc gcggggtgaa ggcgacggcg tccgcgcgca cgcgcaaggc gtcgagcagc
     2101 tcgtcctgcc agcgcgcgcg atcctccagc caggcctcgg tggtgggctg cagcgcgcgg
     2161 ctccacgccg cgatgcgctc gcgctgggcc ggcgtcatgc ggccgaacca gcgccgcagg
     2221 cgctcttcca tgcgctcgac gcgggcggcg tgctgcgcgg ccgcgtcgcc ggagaggaac
     2281 tccgcgcgcg cctcctcgcc acggcgggcg aaggacgcgg cgagctcctc cacctgctcg
     2341 tcgctcaggc cggccagcag cgcgcgcagc tcgggctcga gctcggcgac gatctcgcgc
     2401 cacagcgcct cgccgcgctc gaggaagggt tcgagctgcg ccgcctcgac gcgctcgctc
     2461 gccagcgtcg tgttcgccgc gcgcaacagg gcgacgtact cgggcagatg gctacggcag
     2521 tgccagtcga gcaggccggc aaggcgcaca tccagctcgc tgcgctggcc ggcgttcagc
     2581 gtgacgtagt cgcgcagata ccacggcagc agccagtcga gctgcgaata ggcgaagcgc
     2641 aacccgcagc cggcgagcag gagcgcgctg caggcgatca ggatcaggcg gcggagcggg
     2701 cgagcgggca tgcggcgtga gaccgcgccg ggcgcgggcg gttcgcccgc gccgtccgtt
     2761 cgaccgcttc agcgtgcctc ggcgcggggc tcggcactcg actccgctgc ggccgcctca
     2821 gccgcgccct cggcgcggcg cacacgctcg gcggcatccg cgtcagcggc ttcggtctcg
     2881 ggctccactg cgccgaaagc agccggcgcg gtcgcggccg cctcgtgctc gaccgcgggc
     2941 gcttcggcag tcgctgccac gctcgcctgg gcgggctcgg ggaggacctc ggcctccgca
     3001 gccagcgcag gcgccgcatc cgccacggtg gccggcacaa cttcggccac ggtctcgacc
     3061 gccggctcca cctccgctcc ggcatccggg ctcgccgctg cggcggccgt cgccgccccc
     3121 gcgagcagcg cgccggatgc ggccggctcg accacgcggc ggggcagcag cgcatcgacg
     3181 cgctcctgga agcgctcacg cgccgaggcg ccggagagct tgtcgtagcc tgcggacagg
     3241 tgctcgaaga gctccttgta cgagcccgcc atcgacacga acagggtcgc agtcttgtcg
     3301 aagtgggcgt cgacctcctt gcggtagcgc tcggcctcct cgctcttgcg cgccagttcg
     3361 gcctcgagct cgtcgatgcg ccctttggtg ccggcgctcg agcgcccgac gaagaacgcg
     3421 atcacgccga cgatgacgac ggcggagatg gcgagcagcc aggcggtttg cggggtcatg
     3481 tccatgttgt cctccctcct ttgtggatct caatcgacca ccgtcgcctc caccggcgac
     3541 gggaactgca ggcgcgcgcg caactcgcgg gtgacctcga tgcgaccgtc cgcggccacg
     3601 cgcagtgcat gttcgatgcc gaaacggcga atctgttcgc gccagccgtc gccggcgaga
     3661 taggccggct tgctcggcgc gtccgacagc gtcccggcct tggcgcgcgc ggtgacgagc
     3721 acggtgagcg actgcgtgcc gtgcgcgggc tggccggtgc gcgggtcgag caggtgggcg
     3781 taacgctcgc cgtcgagctc gaagtagcgc tggtagtcgc ccgaggtgcc gatcgcctcg
     3841 ccgtcgtaga gcggcagggt agcgagcggc gcgggcgcgc gcgggtgctg gatgccgatc
     3901 cgccacggct gatcgccctt gccgccgagg gccatgacgt tgccgccgat gttgatgagc
     3961 gcgttgacgg tgcccgcttc ccgcaggatc gccgcggcgc ggtcgagcgc gtagcccttg
     4021 gcatagccgc cgagatcgag ctgtaccgcg cggttgccgc tctcgacccg gttgccgtcg
     4081 atgacgaggt cggccatcga ggggcgcgcg gcgagcaggg cctgcagcct gtcggggtcg
     4141 gggcgctgcg gcacgaagct gtcgctgtgg aagccccaca gcgcgaccag gccgccgagc
     4201 gcggggtcga agaggccgtc gccggtggcg gcgatcgcct gcgcgtcctt cagcatcgcg
     4261 gcgagctcgt cggacacggt ggcggcctcg ccgcgcgcga tcgcggcgtt gagcgcggtg
     4321 agctcggagg gctcccaggc gtggtaggcg cgatgcaggc ggtcgaactc gcgcagcacc
     4381 gcggcggcgg cgcggtcggc ctcggcctgg ttctccccat acaccgcgac gtcgacccgg
     4441 gtgccgaaga cgtaggcctc gtgatggaag acctgcgcgc gcgagcaggc cgcgagcagc
     4501 agcgcacagg ctaccaacgc gaggacgcgc agcgcgtccg ccacagcacg cggatcggag
     4561 aaggcggaga ggctcgggcg caggctcagc cgcacgcccg ctccagcttg tcgatcacca
     4621 ggccggcgac gtcgaagccc tgctgggtgg cgatctccac catgcaggtg gggctggtga
     4681 cgttgatctc ggtgagatgg ccgccgatca cgtcgaggcc gacgatcagc agtccgcgcg
     4741 cccacagcgt cggcgcgagg aactcggcga tctcgcgctc gcgcgcggtg agcgccatcg
     4801 ccacgccgcg cccgccggcg gcaaggttgc cgcgcgtctc gcccgcccgc gggatgcgtg
     4861 cgagcgcgaa gggcacgacc tcgccaccga tgatcagcac gcg
//
LOCUS       DAOTIN010000182         4895 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_20540_length_4895_cov_10.135124, whole genome shotgun
            sequence.
ACCESSION   DAOTIN010000182 DAOTIN010000000
VERSION     DAOTIN010000182.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 4895)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4895)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4895
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_20540_length_4895_cov_10.135124"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..849)
                     /locus_tag="P5537_16155"
     CDS             complement(<1..849)
                     /locus_tag="P5537_16155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004372008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)(+) transhydrogenase (Re/Si-specific)
                     subunit beta"
                     /protein_id="HRV79622.1"
                     /translation="MTSSMATVSYIGATILFILSLGGLAHPETARRGNLFGMIGMALA
                     VLATVFGPQVSAGGIPWIIIALVIGAAVGLYAAKTVQMTQMPELVALMHSLVGLAACL
                     VGYASYVDTATVFPTAAEKTIHEVEIYIGIFIGAITFSGSLIAFGKLSGKIGGKPLLL
                     PARHILNLIGLVLVILFGNWFLNTHSTGAGMTLLLVMTVIALAFGVHMVMAIGGADMP
                     VVVSMLNSYSGWAAAATGFMLSNDLLIVVGALVGSSGAILSYIMCRAMNRNFISVIAG
                     GFGTGGG"
     gene            complement(860..2449)
                     /locus_tag="P5537_16160"
     CDS             complement(860..2449)
                     /locus_tag="P5537_16160"
                     /EC_number="1.6.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004317128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008746 - NAD(P)+ transhydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit alpha"
                     /protein_id="HRV79623.1"
                     /translation="MNLLIGVPKETFAGEKRVATVPEVVVKLVKLGFAVAVESSAGEA
                     ANFADEDYRAAGAEVLPGAADVWARADIVFKVRPPTLEEVAMLREGATLVGFVWPAQN
                     PELMQALQARRATVLAIDCLPRQLSRAQKMDALTSMAGISGYRAVIEAANAFGRFLNG
                     QVTAAGKIPPAKVFIAGAGVAGLAAIGTAANLGAIVRANDTRAEVADQVVSLGGEFVK
                     VDYEEEGSGGGGYAKVMSEGFQAAQRAMYAQQAREVDIIITTALIPGKPAPKLITAEM
                     VQSMKPGSVIVDLAAEQGGNCELTVPGEAVVRHGVTIIGYTDLLSRLAKQSSTLYSNN
                     LLRLAEELCKAKDGNILVNFEDDAIRGLTVIRDGELTWPAPPPKLPAAPAKPKAAATP
                     IAAPKGHGHGAGEPMSVKSLAIVFGVGALLFLLVGLYAPASFLSHFTVFVLACFVGYM
                     VVWNVTPSLHTPLMSVTNAISSIIAIGALVQVAPPLGDGAADRPDGLILFLAFFALAL
                     TAVNMFGGFAVTRRMLAMFRK"
     gene            complement(2754..3500)
                     /gene="phbB"
                     /locus_tag="P5537_16165"
     CDS             complement(2754..3500)
                     /gene="phbB"
                     /locus_tag="P5537_16165"
                     /EC_number="1.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002934093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018454 - acetoacetyl-CoA reductase
                     activity [Evidence IEA];
                     GO_process: GO:0042619 - poly-hydroxybutyrate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetoacetyl-CoA reductase"
                     /protein_id="HRV79624.1"
                     /translation="MSNARVVLVTGGMGGLGEVISTKMSAAGYRVAVTYSPGNTKHAE
                     WVADMKARGHDILAVPCDVADLESCTKAVAEVREKVGEVDVLVNNAGITRDMTFKKMD
                     KVNWDAVLRTNLDSLFNMSKQVVDGMTERGWGRVINVSSVNGSKGAFGQTNYSAAKSG
                     VHGFTKALALEVAKKNVTVNTISPGYIGTKMVMAIPKEVLDSKILPQIPLGRLGKPEE
                     VAGLIIYLASEEAAFVTGANIAINGGQHMQ"
     gene            complement(3536..4711)
                     /locus_tag="P5537_16170"
     CDS             complement(3536..4711)
                     /locus_tag="P5537_16170"
                     /EC_number="2.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HRV79625.1"
                     /translation="MEDVVIVGAARTAVGKFGGALAKVAAPDLGATVIKALLERVGIS
                     GDMVDEVILGQVLTAGGGQNPARQAVIKSGLPIGVPAFVVGKVCGSGLKATHLAAQAI
                     RCGDADIVIAGGQENMSASPHVVMGSRDGQRMGDWKMVDTMINDGLWDAYNHYHMGTT
                     AENVAKKYGISREEQDAFAAASQQKAEAAQKAGRFKDEIVPVEIVSRKGKVVFDTDEF
                     IKHGTTAESLAGLKPAFEKAGSVTAGNASGINDGAAAVLMMSASKAKALGLQPLARIA
                     AYASAGLEPTIMGMGPVPASKLCLHKAGWTADQLDLMEINEAFAAQACAVNKEMGWDT
                     SKINVNGGAIAIGHPIGASGCRVLVTLIHEMIRRDARRGLASLCIGGGMGVALAIER"
BASE COUNT          794 a         1609 c         1606 g          886 t
ORIGIN      
        1 gccgccgccg gtgccgaagc cgccggcgat gacgctgatg aagttgcggt tcatcgcccg
       61 gcacatgatg taggacagga tcgcgccgga ggaacccacc agcgcgccga ccacgatcag
      121 caggtcgttg ctgagcatga agccggtggc cgcagccgcc cacccggagt agctgttgag
      181 catcgacacc accaccggca tgtccgcgcc gccgatcgcc atcaccatgt gcaccccgaa
      241 ggcgagcgcg atcacggtca tcaccagcag cagcgtcatg ccggcgccgg tcgagtgcgt
      301 gttcaggaac cagttgccga acaggatcac cagcacgagg ccgatcaggt tgaggatgtg
      361 gcgcgccggc agcagcagcg gcttgccgcc gatcttgccc gagagcttgc cgaaggcgat
      421 cagcgaaccg gagaaggtga tcgcaccgat gaagatgccg atgtagatct ccacctcgtg
      481 gatggtcttt tcagcggcgg tggggaacac ggtcgcggtg tccacatagc tcgcataacc
      541 gaccaggcag gcggccaggc ccaccaggct gtgcatcagc gcgacgagct cgggcatctg
      601 cgtcatctgc accgtcttgg cggcgtagag gccaaccgcg gcgccgatga cgagggcgat
      661 gatgatccag ggaatgccac ccgcgctgac ctgcgggccg aacacggtgg cgagcaccgc
      721 gagcgccatg ccgatcatgc cgaacaggtt gccgcggcgt gcggtctcgg ggtgggcgag
      781 cccgcccagg ctgaggatga agaggatggt ggcgccgata tacgagacag tggccatgct
      841 tgaggtcatt gtcgtctcct tacttgcgga acatcgccag catgcgacgc gtcaccgcga
      901 agccgccgaa catgttgacg gccgtgagcg cgagcgcgaa gaaggccagg aacaggatca
      961 gcccgtcggg gcggtcggcc gcgccatcgc ccagcggcgg cgccacctgc accagcgcgc
     1021 cgatcgcgat gatcgacgag atcgcgttgg tcacgctcat cagcggcgtg tgcagcgagg
     1081 gcgtgacgtt ccacaccacc atgtagccga cgaagcaggc cagcacgaac accgtgaagt
     1141 gcgacaggaa gctggccggc gcgtacaggc cgacgagcag gaacagcagc gcaccgacac
     1201 cgaacacgat ggccagcgac ttcaccgaca tcggctcgcc ggcgccgtgg ccgtggccct
     1261 tgggcgcggc gatcggcgtg gcggcggcct tgggcttggc cggcgcggcc ggcagcttgg
     1321 gcggcggcgc cggccaggtg agctcgccgt cccggatcac ggtgaggccg cggatcgcgt
     1381 cgtcctcgaa attgacgagg atgttgccgt ccttggcctt gcacagttcc tcggccaggc
     1441 gcagcaggtt gttcgagtac agcgtggacg actgcttggc caggcggctg agcaggtcgg
     1501 tgtagccgat gatggtcacg ccgtggcgca ccaccgcctc gccgggcacg gtcagttcgc
     1561 agttgccgcc ctgctcggcc gcgaggtcga cgatcacgct gcccggcttc atgctctgca
     1621 ccatctcggc ggtgatcagc ttgggcgcgg gcttgcccgg gatcagcgca gtggtgatga
     1681 tgatgtcgac ttcccgcgcc tgctgcgcgt acatcgcgcg ctgcgcggcc tggaagccct
     1741 cgctcatcac cttggcgtag ccgccgccgc ccgagccctc ttcctcgtaa tcgaccttga
     1801 cgaactcgcc accgagcgag accacctggt cggcgacttc ggcgcgggtg tcgttggcgc
     1861 gcacgatggc gcccaggttg gccgcggtgc cgatggcggc gagaccggcc acgccggcgc
     1921 cggcgatgaa gaccttggcc ggcgggatct tgccggcggc ggtgacctgg ccgttgagga
     1981 agcggccgaa ggcgttcgcc gcctcgatca cggcacggta gccactgatg ccggccatcg
     2041 aggtcagcgc gtccatcttc tgcgcccggc tcagttgccg cggcagacag tcgatggcga
     2101 gcaccgtggc gcgcctggcc tgcagcgcct gcatcagctc ggggttctgc gccggccaca
     2161 cgaagccgac cagcgtcgcg ccttcgcgca gcatggcgac ttcttccagc gtaggcgggc
     2221 gcaccttgaa tacgatgtcg gcccgtgccc agacgtcggc ggcgccaggt aatacctcgg
     2281 cgcccgcggc tcggtagtcc tcgtcggcaa agttcgccgc ttctccggcg ctgctttcga
     2341 ccgcgacggc gaaacccagc ttgacgagct tcaccacgac ctcgggaacg gtcgccacgc
     2401 gtttttcacc agcgaaggtt tcctttggaa ctccgatcag caaattcatg gcttcgactc
     2461 ctcaatcgat tgaccttgca ggcgcggctg cgccgagcgg cacgcctcgc cgcgcagccc
     2521 gcggcttcga gctttcggta tcggctctct cgcgaacgtg ggtgccacac gggttccaca
     2581 aagcgtggtt ccatgagcca tgggtgtgtg catcgggttc tccctgttct gtttttttgg
     2641 cgaagcagtg cgtgcgttca agccgagcaa gccgaatgag ctccgacaga cgccatggcc
     2701 aatcgcactc ggagacgtgg cgcgtgtgct ggcggagccc aggcccacat acctcactgc
     2761 atgtgctggc cgccgttgat ggcgatgttg gcgccggtga cgaaggcggc ctcctctgat
     2821 gccaggtaga tgatcaggcc ggccacctcc tccggtttgc cgaggcgccc cagcggaatc
     2881 tgcggcagga tcttgctgtc cagcacttcc ttcgggatgg ccatgaccat cttcgtgccg
     2941 atatagccgg gggagatggt gttgaccgtg acgttcttct tcgccacctc gagcgccagc
     3001 gccttggtga aaccatgcac gccggacttg gctgccgagt agttggtctg cccaaacgca
     3061 cccttgctgc cattgaccga ggacacgttg atgacgcggc cccagccgcg ctcggtcatg
     3121 ccgtcgacca cctgcttgct catgttgaac aggctgtcga ggttggtacg cagcaccgcg
     3181 tcccagttga ccttgtccat cttcttgaag gtcatgtcgc gcgtgatacc cgcgttgtta
     3241 accagcacat cgacctcgcc gaccttctcc cgcacctcgg ccacggcctt ggtacatgat
     3301 tcgagatcgg cgacgtcgca aggcacagcg agaatgtcgt gcccccttgc cttcatgtcg
     3361 gcgacccact ctgcatgttt cgtatttccg ggcgaatacg taacggccac ccggtaacct
     3421 gccgcggaca tcttggtgga gatgacctca cccaggccac ccatgccacc cgtaaccagc
     3481 accacacgtg cattgctcat gttcgtctcc tcagtcgcgt cgttcaggat tggattcagc
     3541 gttcgatggc aagtgcgacg cccattccgc cgccgatgca gagcgaggcg aggccacggc
     3601 gtgcatcgcg ccgaatcatt tcgtggatca gcgtgaccag cacgcggcat ccggatgcgc
     3661 cgatcgggtg cccgatcgcg atcgcgccgc cattgacgtt gatcttgctg gtgtcccagc
     3721 ccatttcctt gtttaccgcg caggcctgcg ccgcgaaggc ttcgttgatc tccatgaggt
     3781 cgagctggtc ggccgtccag ccggccttgt gcaggcacag cttcgaggcg ggcaccgggc
     3841 ccatgcccat gatcgtgggt tcgaggccgg cggaggcgta ggcggcgatg cgggcgagcg
     3901 gctggaggcc gagcgccttc gccttgctcg cggacatcat cagcaccgcg gcagcgccgt
     3961 cgttgatccc cgaggcgttg ccggccgtca ccgaccctgc cttttcgaac gcgggcttga
     4021 ggccggcgag cgattcggcc gtcgtgccgt gcttgatgaa ttcgtcggtg tcgaacacca
     4081 ccttgccctt gcggctgacg atctccacag ggacgatctc gtccttgaag cggccggcct
     4141 tttgcgcggc ctcggccttc tgctgggatg cagcggcgaa ggcatcctgc tcctctcgcg
     4201 agatgccgta ttttttggca acgttttcgg cagtggtgcc catgtggtag tggttgtagg
     4261 catcccacag gccgtcgttg atcatcgtgt cgaccatctt ccagtcgccc atgcgctggc
     4321 catcgcgcga gcccatcacc acatgcggcg aggcgctcat gttctcctgg ccgccggcga
     4381 tgacgatgtc cgcatcgccg caacggatgg cctgcgcggc cagatgggtg gccttgaggc
     4441 ccgagccgca gaccttgccg acaacgaaag ccggcacgcc gatcggcagg ccggacttga
     4501 tcaccgcctg acgcgccggg ttttggccgc cgccggcggt cagtacctgg ccgaggatga
     4561 cctcgtcgac catgtctcca ctgatgccga cgcgttccag caaggccttg atgacggtgg
     4621 cacccagatc aggtgcagcg acttttgcga gtgcacctcc gaacttgcca acagcagtgc
     4681 gcgcggcacc aacgataaca acgtcttcca tggtccgttt cctatctcgt tgaatgacaa
     4741 cctgacctta gctccccttg ttatgagtgg cagatgcctg cctggtatcg ggggggcggt
     4801 cagggttggg gctggggtca gggttggggt tggggggcga agccttactt cttgcgcatc
     4861 ggcggcaggt cggtgcagct gccgtgcgcc acttc
//
LOCUS       DAOTIN010000183         4894 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_20547_length_4894_cov_8.763588, whole genome shotgun sequence.
ACCESSION   DAOTIN010000183 DAOTIN010000000
VERSION     DAOTIN010000183.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 4894)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4894)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4894
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_20547_length_4894_cov_8.763588"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(245..1675)
                     /locus_tag="P5537_16175"
     CDS             complement(245..1675)
                     /locus_tag="P5537_16175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="circularly permuted type 2 ATP-grasp protein"
                     /protein_id="HRV79626.1"
                     /translation="MNAAKPYDEMHAADGTIRTHYQPYDDWLGHTPRELIARKRKEAD
                     LAFHRVGITFNVYGADGGKERLIPFDLLPRIIPGDEWQALEAGLRQRVRALNAFLADI
                     YHDQEILRAGRIPADQVLDNAQFRPEMQGVRVPGGLYAMIAGIDLVRAAGADGKGEYY
                     VLEDNLRVPSGVSYLLENRKMMMRLFPDLFSRYDVQPVEHYPDLLLETLRAVAPAGVL
                     DPTAVLLTPGAFNSAYFEHSFLAQQMGVELVEGQDLFVRDDTVFMRTTQGPKRVDVIY
                     RRLDDDFLDPEVFRPDSMLGVPGLMSAYRAGRVTLANAVGTGVADDKSIYPYVPEMVR
                     FYLGEEPILNNVPTWMLREPDDLAYTLAHLPELVVKEVHGAGGYGMLVGPAATKAEIE
                     EFRQRILAAPEKYIAQPTLSLSTCPTFVDAGIAPRHIDLRPFVLSGGREIRMVPGGLT
                     RVALKAGSLVVNSSQGGGTKDTWVVG"
     gene            complement(1835..2779)
                     /locus_tag="P5537_16180"
     CDS             complement(1835..2779)
                     /locus_tag="P5537_16180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004248805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase family protein"
                     /protein_id="HRV79627.1"
                     /translation="MALYEVLHDTTYHYDSAVSLSQQIAHLRPRESAGQRTLAHHLEI
                     SPVPAQRSERRDFFGNPVTAFALHAPHRELAVRARSRIRVDLPTWPEPAKSPPWEAAR
                     DHLRDGLSGHAPLRADARDAGQYRFASPFVALGDEAARYADYALESFTPGRPVLAALL
                     ALSARIHADFQFDPAATRVATPVAEVFAARRGVCQDFSHLMIACLRALGLAARYVSGY
                     LLTEPPPGQPRLIGADASHAWVALWCPGTGWVDVDPTNDLQPGSGHITLAWGRDYGDV
                     CPLRGVILGGGGHRVDVAVTMMPVDEGEVSLRAADAPD"
     gene            complement(2789..>4894)
                     /locus_tag="P5537_16185"
     CDS             complement(2789..>4894)
                     /locus_tag="P5537_16185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="circularly permuted type 2 ATP-grasp protein"
                     /protein_id="HRV79628.1"
                     /translation="ARVLPELYRAAGVEPLVPFFEGFRDGLADLAPADSAAAGEDPLI
                     VVLTPGPYNETYFEHAYLARELGFPLVEGQDLTVRDDKVWLRTLDGLRRVHVILRRVD
                     DLWCDPLELREDSALGVAGLVAAVRAGTVTVANALGSGILETGALLGYLPRLCEHLLG
                     NKLRMPSVATWWCGEAAACDYALKHLRELVIKPAYPTLGAGPVFCGDLPAAELDALAA
                     RIALRPFDFVAQEMVNISQAPVLAGGEGREGGGGKDAPGREARALVARNIGLRVFAAA
                     GAEGFRVLPGGLVRVASEADMRIVSMQHGGGSKDAWVLGSPARPRPLPRIVPGQLAPF
                     AGGARVLGLSSRVAENFFWLGRYSERADAAARLGRETLARLGEAGEASWLGEDGKVTA
                     ALQALCRQRGLLAALARETDAASDPAAMTPPASQPPSADKPASQSRTPEPPPAPLAQA
                     LFDPAQPGSVVANLRQVLRLAALVRDRLSPDSWRIYNRLSEFAAAPAHPLRLGEAQQR
                     LDESLLSLVTLSGFVIESMPRDAGWRFLSIGRRIERLQFLAAALSALLLAPSQGGLRV
                     LLAITDAELRYRSRHARGLAPQPVAELVMLDGDNPRALRYQLDSLAEHVALLPDGAVL
                     AVPLRERLAALDALALYDCFVHELAGTRARPATQARHCEPLRQVLEEIWRCGNELADA
                     LARRYFTHLDARSRATVSL"
BASE COUNT          709 a         1715 c         1827 g          643 t
ORIGIN      
        1 cgcctgccgg cgctcctaca caaacgtcgc ggtggggcgg gcgcctgggg gcgttcgtac
       61 cgccgtgttc gcgcctgccg gcgctcctac aaaaacgtcg cggcggggcg ggcgcctggg
      121 ggcgttcgta cctccgtgtt cgcgcctgcc ggcgcgccta cctatgcgtc gcggcggggg
      181 gcgttcgcga cgtcgcagtc gcgcctgacc ctgtaggagc gccggcaggc gcgaacatgg
      241 cgcttcagcc caccacccag gtgtccttgg tgcccccgcc ctgcgaggaa ttgaccacca
      301 gcgagccggc cttgagcgcg acgcgggtca ggccgccggg caccatgcgg atctcgcgtc
      361 cgcccgaaag cacgaagggg cgcaggtcga tgtggcgcgg cgcgatgccg gcatcgacga
      421 aggtcggaca ggtcgacagc gacagcgtgg gctgggcgat gtacttctcc ggcgcggcga
      481 ggatgcgctg gcggaactcc tcgatctcgg ccttcgtcgc cgccggcccg accagcatcc
      541 cgtagccgcc ggcgccatgg acctccttga ccaccagctc gggcaggtgg gcgagcgtgt
      601 aggcgaggtc gtccggctcg cgcagcatcc aggtcgggac gttgttgagg atcggctcct
      661 cgccgaggta gaagcgcacc atctcgggca cgtaggggta gatcgacttg tcgtcggcca
      721 ccccggtgcc gaccgcgttg gccagcgtca cccgccccgc acggtaggcc gacatcagcc
      781 cgggcacgcc gagcatcgaa tcggggcgga agacctcggg gtcgaggaag tcgtcgtcca
      841 gccggcggta gatcacgtcg acccgcttcg gcccctgggt ggtgcgcatg aacacggtat
      901 cgtccctgac gaagaggtcc tggccctcga ccagctccac ccccatctgc tgggccagga
      961 agctgtgctc gaagtaggca ctgttgaagg cgcccggggt cagcagcacc gcggtggggt
     1021 cgagcacgcc ggccggcgcc accgcgcgca gggtctcgag cagcaggtcg gggtagtgct
     1081 cgacgggctg cacgtcgtag cgcgagaaca ggtcggggaa gagccgcatc atcatcttgc
     1141 ggttctccag caggtagctc acccccgagg gcacgcgcag gttgtcctcc agcacgtagt
     1201 actcgccctt gccatcggcg cccgcagcac gcaccaggtc gatgccggcg atcatcgcgt
     1261 acaggccgcc gggcacgcgc acgccctgca tctcggggcg gaactgggcg ttgtccagca
     1321 cctggtcggc ggggatgcgg ccggcacgca ggatctcctg gtcgtggtag atgtcggcga
     1381 ggaaggcgtt gagggcgcgc acgcgctgcc gcaggccggc ctcgagcgct tgccattcgt
     1441 cgcccgggat gatgcgcggc agcaggtcga aggggatcag gcgctccttg ccgccgtcgg
     1501 cgccatagac gttgaaggtg atgccgacgc ggtggaaggc gaggtcggcc tccttgcgct
     1561 tgcgcgcgat cagctcgcgc ggggtgtgtc cgagccagtc gtcgtagggc tggtagtgcg
     1621 tgcggatcgt gccgtcggcg gcgtgcattt cgtcgtaggg cttggcggcg ttcatggcgt
     1681 gctctgcgcg gatggtttat cgactccctc gcagggctta cagcagaaag cgtgccaatc
     1741 ccgtcaagcg tgcaaagccg cgccggcaaa ggggtcggac gcgtggtcgc ctgcgggcac
     1801 cgcgctggtg cgcaccagcg tggcctttcg tgcctcaatc tggtgcgtcg gctgcgcgca
     1861 aggagacctc gccctcgtcc accggcatca tcgtcaccgc cacgtccacg cggtgcccgc
     1921 cgccaccgag gatgacgccg cgcagcgggc acacgtcgcc gtagtcccgc ccccaggcca
     1981 gcgtgatatg gccgctgccc ggctgcaggt cgttggtcgg gtcgacgtcg acccagcccg
     2041 tgcccgggca ccacagcgcc acccaggcgt gcgaggcgtc ggcgccgatc aggcgcggct
     2101 ggccgggcgg aggctcggtg agcaggtagc cggagacgta gcgcgcggcc agcccgagcg
     2161 cacgcaggca ggcgatcatc aggtgcgaga agtcctggca caccccgcga cgcgcggcga
     2221 agacctcggc caccggggtg gcgacgcggg tcgccgcggg atcgaactgg aagtcggcat
     2281 ggatgcgcgc cgagagcgcg agcaaggccg cgagcacggg ccgcccgggc gtgaagctct
     2341 ccagcgcata gtcggcgtag cgcgccgctt cgtcgccgag cgccacgaac ggagaggcga
     2401 agcggtactg gccggcgtcg cgcgcgtcgg cgcgcagcgg cgcatggccg gaaagcccgt
     2461 cgcgcaaatg atcgcgcgcg gcctcccagg gcggactctt cgccggctcg ggccaagtcg
     2521 gcaggtcgac gcggatgcgg ctgcgcgcac gcacggccag ctccctgtgc ggtgcatgga
     2581 gcgcaaaggc ggtcacaggg ttgccgaaga agtcgcggcg ctcgcttcgc tgcgccggca
     2641 cgggcgagat ctcgaggtgg tgcgcgaggg tgcgctggcc ggcactctcg cgcggacgca
     2701 ggtgggcgat ctgctgcgac agcgacaccg cgctgtcgta gtggtaggtg gtgtcgtgga
     2761 ggacctcgta gagcgccatc gtcgccccct acagcgacac ggtcgcccgg ctgcgggcgt
     2821 cgaggtgggt gaagtagcgc cgtgccaacg catcggccag ctcgtttccg cagcgccaga
     2881 tctcctccag gacctggcgc aggggctcgc aatggcgtgc ctgggtggcc ggacgggcgc
     2941 gtgtgccagc cagctcatgc acgaagcagt cgtacagcgc gagcgcatcg agcgcggcca
     3001 ggcgttcgcg cagcggcacg gcgagcacgg cgccatcggg cagcaaggcg acgtgctcgg
     3061 cgagcgaatc gagctggtag cgcagcgcgc gcgggttgtc gccgtcgagc atcaccagct
     3121 cggccaccgg ctgcggggcg aggccgcggg catggcggct gcggtagcgc agctcggcat
     3181 cggtgatcgc gagcagcacc ctgagcccgc cttgcgaagg cgcgagcagc agcgccgaca
     3241 gcgcggcggc gaggaactgc aggcgctcga tgcgccgccc gatcgacagg aagcgccagc
     3301 cggcgtcccg cggcatgctc tcgatgacga agcccgacag tgtgaccagc gacaacagcg
     3361 actcgtccag gcgctgttgc gcctcgccga ggcggagagg gtgggccggc gcagcggcga
     3421 actccgacag gcggttgtag atgcgccagc tgtccggtga caggcggtcg cgcaccaggg
     3481 ccgcgaggcg cagcacctgt cgcaggttgg ccaccacgct gccgggctgc gcggggtcga
     3541 agagcgcctg cgcgagcggc gcgggcggtg gctcgggcgt tcgcgactgg ctggccggtt
     3601 tgtcggctga agggggctgc gacgcgggag gcgtcatggc ggcggggtcg gacgccgcgt
     3661 cggtctccct cgccagcgcg gcgagcaggc cacgctggcg gcacagtgcc tgcagcgccg
     3721 cagtcacctt gccatcctcg cccaaccacg aggcctcgcc ggcctcgccc aggcgcgcca
     3781 gcgtctcgcg gccaaggcgt gcggcagcgt cggcacgctc gctgtagcgg ccgagccaga
     3841 agaagttctc cgccacccgg ctcgacagcc cgagcacgcg cgcgccgccg gcgaacggcg
     3901 cgagctggcc gggcacgatg cgcggcagcg gacggggtcg cgccggcgag ccgagcaccc
     3961 aggcgtcctt gctgccaccg ccatgctgca tcgacacgat gcgcatgtcg gcctccgagg
     4021 ccacccgcac gagcccgccc ggcagcacgc gaaagccctc cgcgcccgcc gctgcgaaca
     4081 cgcgcagccc gatgttgcgc gccaccagcg cacgcgcctc gcgcccgggt gcgtccttcc
     4141 cgccgccgcc ttccctgccc tccccgcccg caagcaccgg cgcctgggag atgttcacca
     4201 tctcctgggc gacgaagtcg aaggggcgca gcgcgatcct cgccgccagc gcgtcgagct
     4261 ccgccgccgg caggtcgccg cagaacacgg gccccgcacc cagggtaggg taggccggct
     4321 tgatcaccag ctcgcgcaga tgcttcagcg cgtagtcaca ggccgccgcc tcgccgcacc
     4381 accaggtcgc caccgagggc atgcgcagct tgttgccgag caggtgctcg cacagccgcg
     4441 gcaggtagcc gagcagcgcg ccggtctcga ggatgccgct gccgagcgcg ttggccaccg
     4501 tcaccgtgcc ggcacgcacc gccgccacca ggccggcgac gccgagcgcg gagtcctcgc
     4561 gcaactcgag cgggtcgcac cagaggtcgt ccacccggcg caggatcacg tgcacgcggc
     4621 gcaggccgtc gagcgtgcgc agccagacct tgtcgtcgcg cacggtgagg tcctggccct
     4681 cgacgagcgg gaagcccagc tcgcgcgcga ggtaggcgtg ctcgaagtag gtctcgttgt
     4741 agggcccggg ggtgagcacc acgatcaggg ggtcttcgcc ggccgccgcg ctgtcggccg
     4801 gcgccaggtc ggcgaggccg tcgcggaagc cctcgaagaa gggcaccagc ggttccacgc
     4861 cggcggcgcg gtagagctcg ggcagcacgc gcgc
//
LOCUS       DAOTIN010000184         4880 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_20626_length_4880_cov_10.321036, whole genome shotgun
            sequence.
ACCESSION   DAOTIN010000184 DAOTIN010000000
VERSION     DAOTIN010000184.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 4880)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4880)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4880
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_20626_length_4880_cov_10.321036"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(11..86)
                     /locus_tag="P5537_16190"
     tRNA            complement(11..86)
                     /locus_tag="P5537_16190"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(51..53),aa:Phe,seq:gaa)
     gene            complement(153..1652)
                     /locus_tag="P5537_16195"
     CDS             complement(153..1652)
                     /locus_tag="P5537_16195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase N-terminal
                     domain-containing protein"
                     /protein_id="HRV79629.1"
                     /translation="MLPLRRKSRPERAPRGANPPRKSGPPNSLFGEILDWMLAPLLFL
                     WPISIIVTHNVADSIANQPYDLALADGVRALARLVEVEDEQIVVRFPAPPRALFRADQ
                     DDVVYFQVADVNGVTVSGDAEIPPMPTSSAQEGEEVQLRDGMIHGEEVRIAWRFVRPD
                     AAQADRFVLVQVAETRNKRTDLASRVVTGVLLPQFAIIPLAVVLVWVGLSRGIAPLNR
                     LQSLIRRRRPTDLSPVEPSSVPEEVRPLIIAYNDMMARLEENLQAQQRFIADAAHQMR
                     TPLTGLKMQTDLAMHETDPDQLRQSLTRIAESTDRAAHLINQLLSLARAEASFEKLYA
                     VETVDLDAIVREVALELYPRAQAKQIDLGVEAGDQALRVEGNPVLLREMLKNLVDNAI
                     KYTPRGGSVTARTRYAGSPVFEVEDSGPGIPEADRERVFERFYRVLGSGVDGSGLGLP
                     IVREIAELHRGTVTLDAGPGGRGTLARVVFPRSHLQPPARVQGDHDALG"
     gene            complement(1621..2313)
                     /locus_tag="P5537_16200"
     CDS             complement(1621..2313)
                     /locus_tag="P5537_16200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HRV79630.1"
                     /translation="MRILLAEDDPVIADGICRALRRGGCAVDHVADGMEADAALAGQG
                     YDLLILDLGLPRMNGIEVLKRLRTRKSAQPVLILTAQDGVDDRVRGLDAGADDYLTKP
                     FALPELEARVRALTRRGTGQPRCIEIGQLSYDQADRVVKIGGQLVELSAREIGLLEIF
                     LLRVGRLVSKDQLVDHLCGWGEEVSSNAIEVYVHRLRKKLEDSGVRIVTVRGLGYCLE
                     NPDAAPAAKVQA"
     gene            complement(2659..4308)
                     /gene="groL"
                     /locus_tag="P5537_16205"
     CDS             complement(2659..4308)
                     /gene="groL"
                     /locus_tag="P5537_16205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011764708.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HRV79631.1"
                     /translation="MAAKEVKFGDSARERMVAGINILANAVKVTLGPKGRNVVLERSF
                     GAPTVTKDGVSVAKEIELKDKFENMGAQMVKEVASKTSDIAGDGTTTATVLAQSIVRE
                     GMKFVAAGMNPMDLKRGIDKAVIATIDELKKLSKPCSTNKEIAQVGSISANSDSDIGE
                     IIARAMDKVGKEGVITVEDGKSLQNELDVVEGMQFDRGYLSPYFINNPDKQVAILEQP
                     FVLLFDKKISNIRDLLPVLEQVAKSGRPLLIIAEDVEGEALATLVVNNIRGILKTCAV
                     KAPGFGDRRKAMLEDIAILTGGQVIAEEVGLTLEKATLDDLGQAARIEVGKENTIIID
                     GAGHAERIEARVKQIRVQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEK
                     KARVEDALHATRAAVEEGIVPGGGVALLRARAALGELKGDNHDQDAGIKIVLRAMEQP
                     LREIVANAGDEPSVVVNKVVEGSGNFGFNAATGEYGDMVEMGVLDPTKVTRTALQNAA
                     SVAGLMLTTDCMVGELAEEKPMGGMPDMGGMGGMGGMGMGM"
     gene            complement(4367..4657)
                     /gene="groES"
                     /locus_tag="P5537_16210"
     CDS             complement(4367..4657)
                     /gene="groES"
                     /locus_tag="P5537_16210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011764707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HRV79632.1"
                     /translation="MKIRPLHDRVIVKRLEAERKTASGIVIPDSAGEKPDQGEVLAVG
                     NGKILDDGKVRPMAVKVGDKVLFGKYAGQTVKVEGEELLVMREEDIMGVVEA"
BASE COUNT          719 a         1621 c         1644 g          896 t
ORIGIN      
        1 tcgggattct tggtggccag tcgcggaatc gaaccacgga cacgcggatt ttcaatccgc
       61 tgctctacca actgagctaa ctggccaacg aggtccgcat tatagccagt ctttttccct
      121 tgtcaaaggc ttttccaaaa aatcgcctcg gctcagccca gcgcgtcgtg atcaccctgc
      181 actcgagccg gcggctgcag gtggctgcgc gggaagacca cgcgggccag cgttccgcgc
      241 ccgccggggc cggcgtccag ggtgaccgtg ccgcggtgca gttcggcgat ctcgcgcacg
      301 atcggcaggc cgaggcccga gccgtcgacg ccgctgccga gcacgcggta gaagcgctcg
      361 aacacgcgct cgcggtcggc ctcggggatg cccgggccgc tgtcctcgac ctcgaagacc
      421 ggcgagccgg cgtagcgggt gcgcgcggtg acgctgccgc cgcgcggggt gtacttgatc
      481 gcgttgtcga ccaggttctt gagcatctcg cgcagcagca ccgggttgcc ctccacgcgc
      541 agggcctggt cgccggcctc gacgccgagg tcgatctgct tggcctgcgc gcgcgggtag
      601 agctcgagcg ccacctcgcg cacgatcgca tcgaggtcca ccgtctccac cgcatagagc
      661 ttctcgaagc tcgcctcggc ccgcgcgagc gacaagagct ggttgatgag gtgggcagcg
      721 cggtcggtgc tctcggcgat gcgggtgagc gactggcgca gctggtcggg gtcggtctcg
      781 tgcatggcga ggtcggtctg catcttgaga ccggtcagcg gcgtgcgcat ctggtgcgcg
      841 gcgtcggcga tgaagcgctg ctgcgcctgc aggttctcct ccaggcgcgc catcatgtcg
      901 ttgtaggcga tgatgagcgg gcgcacctcc tcgggcacgc tggagggctc gaccggcgac
      961 aggtcggtgg ggcgacggcg gcggatcagg ctctgcagcc gattcagcgg cgcgatgccg
     1021 cggctcaggc ccacccacac cagcaccacg gcgagcggga tgatggcgaa ctgcggcagc
     1081 agtaccccgg tgaccacacg cgaggcgagg tcggtgcgct tgttgcgcgt ctcggcaacc
     1141 tgcacgagca cgaagcgatc ggcctgcgcg gcatcgggac gcacgaagcg ccaggcgatg
     1201 cgcacctcct cgccatggat catgccgtcg cgcagctgca cctcctcacc ctcctgcgcg
     1261 gacgaggtcg gcatcggcgg gatctctgca tcgccgctca cggtgacgcc attgacgtcg
     1321 gccacctgga aatacacgac gtcgtcctgg tcggcgcgga acagcgcgcg cggcggcgcg
     1381 ggaaagcgca ccacgatctg ctcgtcctcg acctcgacca agcgcgcgag cgcacgcacg
     1441 ccgtcggcga gcgcgaggtc gtagggctgg ttggcgatgc tgtcggcaac gttgtgggtg
     1501 acgatgatcg agatcggcca caggaacagc agcggcgcga gcatccagtc gaggatctcg
     1561 ccgaacagcg agttcggcgg cccggacttg cgcggcgggt tggcgccgcg cggcgcgcgc
     1621 tcaggcctgg actttcgccg caggggcagc atcggggttt tccaggcagt accccaggcc
     1681 acgcacggtc acgatgcgca ccccgctgtc ctcgagcttc ttgcgcaggc gatggacata
     1741 gacctcgatg gcgttgctcg acacttcctc gccccagccg cacaggtggt cgacgagctg
     1801 gtccttgctg accaggcggc cgacgcgcag caggaagatc tcgagcaggc cgatctcgcg
     1861 cgccgacagc tcgaccagct ggccgccgat cttgaccacg cggtcggcct ggtcgtagct
     1921 cagctggccg atctcgatgc agcgcggctg gccggtgccg cggcgggtga gcgcgcgcac
     1981 gcgcgcctcc agctcgggca gggcgaaggg cttggtgagg tagtcgtcgg caccggcgtc
     2041 gagcccgcgc acacggtcgt cgacaccgtc ctgcgcggtc aggatcagca ccggctgggc
     2101 cgacttgcgc gtgcgcaggc gcttgagcac ctcgatgccg ttcatgcgcg gcaggccgag
     2161 gtcgaggatg agcaggtcgt agccctgccc cgcgagggcg gcgtccgcct ccatgccgtc
     2221 cgccacgtga tcgaccgcgc agccgccgcg ccgcagggcg cgacagatgc cgtcggcgat
     2281 caccggatcg tcttccgcca acaggatacg catagcattc cggttgtaag ttgcttgtaa
     2341 gcggagattc cgagaatggc tccgctgttc tccttttgct cggtctccgg gggcgtggct
     2401 gccttgcgca gcagcgttcc ggggagcgcc cgcccgcctg ggacgtggcg ctccccaccg
     2461 acttttactc cccgaatcgc gccattatcc cacgcttcat gcgcctgcag gcaggccctg
     2521 gcagccccgg ggcgggctgc gcgcgccatt ccggcgccgc cggacgcaaa aaggcctcgc
     2581 cgagatgttt ccccggcgag gcctttcttg tttgcagcag gcgggaggtc cggcgaaccg
     2641 gccctcccgg gcgggcaatt acatgcccat gcccatgccg cccatgccac ccatgccgcc
     2701 catgtcgggc atgccgccca tcggcttctc ttcggccagc tcaccgacca tgcagtcggt
     2761 ggtgagcatc aggccggcga ccgaagcggc gttctgcagc gcggtgcggg tgaccttggt
     2821 cggatccagc acgcccatct cgaccatgtc gccgtactcg ccggtggcgg cgttgaagcc
     2881 gaagttgccc gagccctcga cgaccttgtt caccaccacg ctcggctcgt cgccggcgtt
     2941 ggcgacgatc tcgcgcaggg gctgctccat ggcgcgcagc acgatcttga tgccggcgtc
     3001 ctggtcgtgg ttgtcaccct tgagctcgcc cagcgcggcg cgggcacgca gcagcgcgac
     3061 gccgccgccc gggacgatgc cctcttccac cgcagcgcgg gtggcgtgca gggcgtcttc
     3121 cacgcgagcc ttcttctcct tcatctcgac ttcggtggcg gcaccgacct tgatcaccgc
     3181 gacaccgcca gccagcttgg ccacgcgctc ctgcagcttc tcgcggtcgt agtcggaggt
     3241 ggcttcctcg atctgcacgc ggatctgctt gacgcgcgcc tcgatgcgct cggcatggcc
     3301 ggcgccgtcg atgatgatgg tgttttcctt gccgacttcg atgcgggcag cctggccgag
     3361 gtcgtccaga gtggccttct cgagggtcag gccgacttcc tcggcgatga cctggccgcc
     3421 ggtcaggatg gcgatgtctt ccagcatggc cttgcgacgg tcgccgaagc ccggggcctt
     3481 gacggcgcag gtcttcagga tgccgcggat gttgttcacc accagggtgg ccagggcttc
     3541 gccttcgacg tcctcggcga tgatcagcag cggacggccc gacttggcga cctgctcgag
     3601 caccggcagg aggtcacgga tgttggagat cttcttgtcg aagagcagga cgaagggctg
     3661 ctcgaggatg gcgacctgct tgtccgggtt gttgatgaag tagggcgaca ggtagccgcg
     3721 gtcgaactgc atgccctcga ccacgtcgag ctcgttctgc agcgacttgc cgtcctcgac
     3781 ggtgatcacg ccttccttgc cgaccttgtc catggcacgg gcgatgatct cgccgatgtc
     3841 gctgtcggag ttggccgaga tcgagccgac ctgggcgatc tccttgttgg tcgagcacgg
     3901 cttggacagc ttcttgagct cgtcgatggt ggcgatgacg gccttgtcga taccgcgctt
     3961 gaggtccatc gggttcatgc cggcggcgac gaacttcatg ccttcgcgca cgatggactg
     4021 cgccagcacg gtggcggtgg tggtgccgtc accggcgatg tcggaggtct tggaagcgac
     4081 ttccttgacc atctgcgcgc ccatgttctc gaacttatcc ttgagctcga tttccttggc
     4141 gacggagacg ccgtccttgg tcacggtggg ggcgccgaac gagcgctcga gcaccacgtt
     4201 gcggcccttc gggcccaggg tcaccttgac cgcgttggcg aggatgttga tgccggcgac
     4261 catgcgctcg cgggcggaat caccaaactt gacttcttta gctgccattg ttcaaaactc
     4321 cggaatggtt tgcggttcgc gttcgtgctt caggatcggg ggaggctcag gcctcgacca
     4381 cgcccatgat gtcttcctcg cgcatgacga ggagctcttc accttcgacc ttcacggtct
     4441 ggccggcgta cttgccgaac agcaccttgt cgcccacctt gacggccatc ggacggacct
     4501 tgccgtcatc gaggatcttg ccgttgccga ccgcgaggac ttcgccctga tcgggcttct
     4561 cgccggcgct gtccgggatc acgatgccgc tggcggtctt gcgttcggct tcgaggcgct
     4621 tgacgatcac acgatcatgc aggggacgaa tcttcatcga gttctctcct aactgagttt
     4681 caactgtctg ggttgatgga agatgcggaa ccagtccgcg aaaaacggat ctgcagtggc
     4741 ttcggacggg ttcgcacccg tcgatcgagg cttgttagca ctcaccgcca acgagtgcta
     4801 ataataggga cgggtcccgg ggatttcaag tgcgcttcct gttaactttt ttctgcgccg
     4861 tgatcgcttt cggcgcagct
//
LOCUS       DAOTIN010000185         4872 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_20678_length_4872_cov_7.607224, whole genome shotgun sequence.
ACCESSION   DAOTIN010000185 DAOTIN010000000
VERSION     DAOTIN010000185.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 4872)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4872)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4872
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_20678_length_4872_cov_7.607224"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1808
                     /gene="polA"
                     /locus_tag="P5537_16215"
     CDS             <1..1808
                     /gene="polA"
                     /locus_tag="P5537_16215"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018991847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HRV79633.1"
                     /translation="RKGYVAILDWPTFDAWLAKISAAALTAFDTETTSLDPMAAKLVG
                     MSFAVEPGEAAYLPLAHRAADAPVQLPLDEVLEKLRPWLESDQHAKLGQNLKYDAHVL
                     ANHGIRLGGIEHDTLLESYVLASDKSHDMDSLAKRHLGLATIPYTDVCGKGAKQIGFD
                     EVDVARATEYAAEDADVTLRLHRQLYPQLQALPQLDTLYRELEMPALGVLQRMERTGV
                     LIDPFLLSQHSEELGRRLHALEGEAHTLAGQPFNLGSPKQLGEILFGKLGLPVVKKTA
                     TGQPSTDEEVLEKLAEDYPLPKLLLEHRSLSKLKSTYADKLPRMVDPRTGRVHTSFSQ
                     ATAVTGRLSSSEPNLQNIPIRTPEGRRIRAAFIAPREHLIVSADYSQIELRIMAHLSD
                     DARLLEAFANGEDVHRATAGEVFGVAPAEVSSEQRRYAKVINFGLIYGMSAHGLAKNL
                     GIERAAAQSWIDRYFARYPGVAEYMDRTRAEARDKGFVETVFGRRLYLPDIRASQAGR
                     RAGAERAAINAPMQGTAADLIKRAMIATDAWLAASGLKSKLVLQVHDELVLEVPKVEL
                     DTVRAELPRLMGGVAALKVPLLVEVGAGDNWDEAH"
     gene            1954..3711
                     /gene="msbA"
                     /locus_tag="P5537_16220"
     CDS             1954..3711
                     /gene="msbA"
                     /locus_tag="P5537_16220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004376042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005319 - lipid transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006869 - lipid transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid A export permease/ATP-binding protein
                     MsbA"
                     /protein_id="HRV79634.1"
                     /translation="MKVYLRLLGYTRPFLGYFALSILGFAIAGACKAGLASVLKYFID
                     GLAAPDAPIATGLPWLDALDLIFAIPAMIVVIALVEGLGTFLGNYGISRVSLGLIHDL
                     RTQLFGSFLVLPNRFYDANNSGHLVSKLTYNVSMVTDAATDAVKILFREGLTVIALLS
                     YLLWMNWRLTLTLLVVLPAIAWLVSNASRKFRRLSKNIQTSMGEVTHVASETIQGYRV
                     VRSFGGEDYERARFVKASTHNTKRQLKMVRTQETFSALMHLIVYSSMGLLLFTVLKVR
                     GDASAGDVVAYITAAGLLPRAIQLLGGVSARIQRGVAAADSIFEQLDEAPEPDGGTVE
                     RARIAGRVEARGLGFGYPGAEGRALHGIDFQAEPGQMIALVGKSGSGKSTLANLIPRF
                     YQHDEGRLLVDGVAVEDYTLANLRHHIALVTQQVTLFNGTVAENIAYGELAGASREQV
                     VAAAEAANAREFIDRLPQGFDTEIGENGVLLSGGQRQRLAIARALLKNAPILILDEAT
                     SALDTESERLIQAAIERLMEGRTTIVIAHRLSTIEKADQILVMEAGRIVERGTHADLV
                     ARGGTYARLQAMGIEPDAP"
     gene            complement(4082..4618)
                     /gene="rfbC"
                     /locus_tag="P5537_16225"
     CDS             complement(4082..4618)
                     /gene="rfbC"
                     /locus_tag="P5537_16225"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004356853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HRV79635.1"
                     /translation="MNVIETALPGVLIIEPKAFGDHRGFFLETFQVERYREAGITLPF
                     VQDNHSRSQRGVLRGLHFQKTRPQGKLVSVSRGAVYDVAVDIDPASATYGQFVGVELN
                     DDNHRQLWIPPGYAHGFCVLSEVADFQYKCTDFYFPADEGGLLWNDPDVGIPWPITEP
                     QLSAKDANNPRLRDLKPM"
     gene            complement(4615..>4872)
                     /locus_tag="P5537_16230"
     CDS             complement(4615..>4872)
                     /locus_tag="P5537_16230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="HRV79636.1"
                     /translation="GDLHVSLLGRGFAWLDTGTHDSLMEASHFVQTIEARQGLKVACL
                     EEIAYHQGWLSAAQLARQAEALSKTGYGQYLQRLLRQEVVR"
BASE COUNT          746 a         1809 c         1598 g          719 t
ORIGIN      
        1 accgcaaggg ctacgtcgcc atcctcgact ggccgacctt cgatgcctgg ctggcgaaga
       61 tctccgccgc cgcgctcacc gccttcgata ccgagacgac cagcctcgat ccgatggcgg
      121 cgaagctggt ggggatgtcg ttcgcggtcg agccgggcga ggcggcctac ctgccgctgg
      181 cgcaccgcgc ggccgatgcg ccggtgcaac tgccgctcga cgaggtgctg gagaagctgc
      241 gcccctggct ggagtccgac cagcacgcca agctcgggca gaacctcaag tacgacgccc
      301 acgtgctcgc caaccacggc atccggctcg gcggcatcga gcacgacacc ctgctcgaat
      361 cctatgtgct cgcgagcgac aagtcgcacg acatggattc gctcgccaag cgccacctgg
      421 gcctcgcgac gatcccctat acggatgtct gcggcaaggg cgccaagcag atcggcttcg
      481 acgaggtgga cgtggcgcgc gccaccgaat acgccgccga ggacgccgac gtcaccctgc
      541 gcctgcaccg ccagctctac ccgcagctcc aggccctgcc gcagctcgac acgctctatc
      601 gcgagctcga gatgccggca ctcggcgtgc tgcagcgcat ggagcgcacc ggggtgctga
      661 tcgacccctt cctgctcagc cagcactccg aggagctcgg ccgccgcctg cacgcgctcg
      721 aaggcgaggc ccacacgctc gccggccagc ccttcaacct cggctcgccc aagcagctcg
      781 gcgagatcct gttcggcaag ctcggcctgc cggtggtcaa gaagaccgcc accggccagc
      841 cctccaccga cgaggaggtg ctggagaagc tcgccgagga ctacccgctg cccaagctgc
      901 tgctcgagca ccgcagcctg tccaagttga agagcaccta cgccgacaag ctgccgcgca
      961 tggtcgaccc caggaccggc cgcgtgcaca ccagcttctc gcaggccacc gcggtcaccg
     1021 gccggctgtc gagctccgag cccaacctgc agaacatccc gatccgcacg ccggagggcc
     1081 gccgcatccg cgccgccttc atcgcgccgc gcgagcacct catcgtctcg gccgactact
     1141 cgcagatcga gctgcgcatc atggcccacc tgtcggacga cgcccgcctg ctcgaagcct
     1201 tcgcgaacgg cgaggacgtg caccgcgcca ccgccggcga ggtcttcggc gtggcgccgg
     1261 ccgaggtcag cagcgagcag cgccgctacg ccaaggtgat caacttcggc ctcatctacg
     1321 gcatgagcgc gcacggcctg gcgaagaacc tcggcatcga gcgcgccgct gcgcagagct
     1381 ggatcgaccg ctacttcgcg cgctatcccg gcgtcgccga gtacatggac cgcacccgcg
     1441 ccgaggcgcg cgacaagggc tttgtggaga ccgtcttcgg tcgccgcctc tacctgcccg
     1501 acatccgcgc cagtcaggcc ggccgccgcg ccggcgccga gcgtgcggcg atcaacgcgc
     1561 cgatgcaggg cacggcggcg gacctcatca agcgcgcgat gatcgcgacc gacgcctggc
     1621 tggcggcatc ggggctgaag tcgaagctgg tgctgcaggt gcacgacgag ctggtgctgg
     1681 aggtgcccaa ggtcgaactc gacaccgtcc gcgccgagct gccccggctc atgggcggcg
     1741 tcgccgcgct gaaggtgccg ctgctggtcg aggtcggcgc gggcgacaac tgggacgagg
     1801 cgcactgatg gccgtggcgc gccgtctcct ctctgcagcc gccccgtgtc attgcgcgcg
     1861 atgagctccg caccgaaccc cggctcgtcc gccgccccgg cccccggcgc cggggccgca
     1921 gcgcccgcag cggagaaacc cgccgccagc agcatgaagg tctacctccg cctgctcggc
     1981 tacacccggc ccttcctcgg ctacttcgcc ctcagcatcc tcggcttcgc catcgccggc
     2041 gcctgcaagg caggcctggc gagcgtgctc aagtacttca tcgacggcct ggccgcgccc
     2101 gacgcgccga tcgccaccgg cctgccctgg ctggacgcgc tcgacctcat cttcgcgatc
     2161 ccggccatga tcgtcgtgat cgcgctggtc gaaggcctcg gcaccttcct cggcaactac
     2221 ggcatctcgc gcgtctcgct cggcctcatc cacgacctgc gcacccagct cttcggcagc
     2281 ttcctggtgc tgcccaaccg cttctacgac gccaacaact ccggccacct cgtctcaaag
     2341 ctcacctaca acgtgtcgat ggtgaccgac gcggccaccg acgcggtcaa gatcctgttc
     2401 cgcgagggcc tcaccgtcat cgcgctgctg agctacctgc tgtggatgaa ctggcgcctg
     2461 accctgaccc tgctcgtcgt gctgccggcg atcgcctggc tggtgtcgaa tgccagccgc
     2521 aagttccgcc gcctgtcgaa gaatatccag acctcgatgg gcgaggtcac ccacgtcgcc
     2581 tccgagacca tccagggcta ccgcgtggtg cgcagttttg ggggcgagga ctacgagcgt
     2641 gcgcgcttcg tcaaggccag cacccacaac accaagcgcc agctcaagat ggtgcgcacg
     2701 caggagacct tctcggcgct gatgcacctg atcgtgtatt cgtcgatggg cctgctcttg
     2761 ttcacggtgc tgaaggtgcg cggcgacgcc tcggccggcg acgtggtcgc ctacatcacc
     2821 gccgccggcc tgctgccgcg cgcgatccag ctgctggggg gcgtgagcgc gcgcatccag
     2881 cgcggcgtgg ccgcggccga cagcatcttc gagcagctcg acgaggcgcc cgagcccgac
     2941 ggcggcaccg tcgagcgcgc acgcatcgcc ggtcgtgtcg aggcccgggg cctgggcttt
     3001 ggctatcccg gcgcggaggg ccgcgcgctg cacggcatcg atttccaggc cgagcccggc
     3061 cagatgatcg cgctggtggg caagtcgggc agcggcaagt ccaccctcgc caatctcatc
     3121 ccgcgcttct accagcacga cgaaggccgg ctactggtcg atggcgtggc ggtggaggac
     3181 tacacgctcg ccaacctgcg ccaccacatc gcgctcgtca cccagcaggt cacgctcttc
     3241 aacggcacgg tcgcggagaa catcgcctac ggcgagctcg ccggcgccag ccgcgagcag
     3301 gtcgttgccg ccgccgaggc cgccaacgcg cgcgagttca tcgaccgcct gccgcagggc
     3361 ttcgacaccg agatcggcga gaacggcgtg ctgctctccg gcggccagcg ccagcgcctg
     3421 gcgatcgcgc gcgcgctgct gaagaacgcg cccatcctga tcctggacga ggccacctct
     3481 gcgctcgaca ccgagtcgga gcggctcatc caggcagcga tcgagcgcct gatggaaggc
     3541 cgcacgacga tcgtgatcgc gcaccggctg tcgacgatcg agaaggccga ccagatcctg
     3601 gtgatggagg ccggccgcat cgtcgagcgc ggcacgcacg ccgatctcgt cgcccgcggc
     3661 ggcacctacg cgcgcctgca ggcgatgggg atcgagccgg acgctccgtg agccctcgtt
     3721 cgcggctgcc gccgctccta cagggtgccg tgccaccagc ccgtctccgc gcccctgtag
     3781 gagcgccggc aggcgcgaat gccgcatcga tcccccgcga cccgtcaccc gccgcgcgcg
     3841 ccttcgcggc tgccgccgct cctacatgca ccgcgcgctc gcccgtctcc gcgcccctgt
     3901 aggagcgccg gcaggcgcga agtcggccat tgaaaaagtt cgcggctggt ggcgctccac
     3961 atggcttccg gaagcgcggt ggttgctgta ggagcgccag aaggcgcgaa tgcggtgccg
     4021 gaaggggcgt ggtacgtgtc tgaacggcac tgttcgcggc tgccgccgct cctacagggg
     4081 gctacatggg tttcaggtcg cgcaggcggg ggttgttggc gtcctttgcc gacagctgcg
     4141 gctcggtgat cggccacggg atccccacgt ccggatcgtt ccagagcagg ccgccctcgt
     4201 ccgccggaaa gtagaaatcg gtgcacttgt actggaagtc cgccacctcg ctcagcacgc
     4261 agaacccgtg cgcgtagccg ggcgggatcc acagctggcg gtggttgtcg tcgttgagct
     4321 ccaccccgac gaactggccg tacgtggccg acgccgggtc gatgtccacc gccacgtcat
     4381 acaccgcccc gcggctcacg ctcaccagct tgccctgcgg gcgtgtcttc tggaaatgca
     4441 gcccgcgcag cacgccgcgc tgcgagcgcg agtggttgtc ctgcacgaag ggcagggtga
     4501 tgcccgcctc gcggtagcgc tcgacctgga aggtctcgag gaagaagccg cggtggtcgc
     4561 cgaaggcctt cggctcgatg atcagcacgc cgggcagcgc ggtctcgatg acgttcaccg
     4621 gaccacctcc tggcgcagca ggcgctggag gtactggccg tagccggtct tgctcagcgc
     4681 ctcggcttgg cgcgccagtt gcgcggccga cagccagccc tggtggtagg cgatctcttc
     4741 caggcaggcc accttcaggc cctggcgggc ctcgatggtc tgcacgaagt ggctcgcctc
     4801 catcagcgag tcgtgcgtgc cggtgtccag ccaggcgaag ccgcgcccga gcaggctcac
     4861 gtgcaggtcg cc
//
LOCUS       DAOTIN010000186         4808 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_21020_length_4808_cov_10.355775, whole genome shotgun
            sequence.
ACCESSION   DAOTIN010000186 DAOTIN010000000
VERSION     DAOTIN010000186.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 4808)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4808)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4808
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_21020_length_4808_cov_10.355775"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(1..1302)
                     /locus_tag="P5537_16235"
     CDS             complement(1..1302)
                     /locus_tag="P5537_16235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011239319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HRV79637.1"
                     /translation="MPVNELLVILLLIAASAFFSMSEISLAASRKIKLRLMAEGGHLN
                     AQRVLALQDSPGHFFTVVQIGLNAVAILGGVVGEQALSPYVSELLRTVYDGPMLGTIA
                     FIVSFVFVTSLFVLFADLMPKRLAMLQPERIAVAVVQPMQVCMWLFAPLVWVFNGAAN
                     LIFRWFKLPSARIEDITADDIMAMADAGAQAGALLRQEQHLISNVFELDSRIVPSAMT
                     SRENIVFLTLSESEESIRRKIAEHPHGKFPVCEDGIDSVIGYVDSKDILPRIVQGQDL
                     SLRTQPIVRKVLMLPDTLTLFEALERFRDAKEDFALILNEYALVVGLLSLQDVMNTVM
                     GDLVSPFQEELIVRRDDNSWLIDGATPIEDVMQALEIEVFEGFQNYETVAGFLMYRLR
                     KVPKRTDFVTYAGYKFEVVDIDNYRIDQVLVTREPAAAATE"
     assembly_gap    1527..1626
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(1782..3461)
                     /locus_tag="P5537_16240"
     CDS             complement(1782..3461)
                     /locus_tag="P5537_16240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006847 - plasma membrane acetate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation acetate symporter"
                     /protein_id="HRV79638.1"
                     /translation="MTARSLSRSAAGLLALAASPLVLAAGPAMDAAEKQPLNLHAIGM
                     FFVFVLMTLGITYWAASRTKSTADFYTAGGGITGFQNGLAIAGDYMSAATLLGLTAMM
                     YAQGVDAYIYMLSFFVGWPIILFLMAERLRNLGKFTFADITAYRLDQGKVRTMAAVSS
                     LTVVCFYLVAQMVGAGQLIKLLFGLDYNIALVVVGALMMVYVTFGGMVATTWVQIIKA
                     CMLLIGGTAVGLLAFSQFGFSFDELTTRAMEVHKLGQKLLNPGSLLADPVTAISLGLG
                     LMFGTAGLPHILMRFFTVTDAKEARKSVLYASGIVAYFFNVIAIMGLCAIIIVGQNPQ
                     FFEGGVIGGKVIGGGNMIAMHLANAVGGNLLLGFLSAVAFATILAVVAGLALAGASAI
                     SHDIYSRVIMKGKANEATELKVSKFATIGLGIVAVLLGMAFEKMNIAFMVALAFGVAA
                     SANFPVLILSMYWKGLTTKGALVGGYSGLVSAVLFVLLSKSVWVDVLGNASAIFPYTQ
                     PALFSMPIAFFMTWLFSTLDSSKAAEAEKEAFEDQYVRAQTGVGAATASSH"
     gene            complement(3461..3769)
                     /locus_tag="P5537_16245"
     CDS             complement(3461..3769)
                     /locus_tag="P5537_16245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002931956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF485 domain-containing protein"
                     /protein_id="HRV79639.1"
                     /translation="MYAHIRRNPRFAELVAKRTRFAGILAAIVLVVFYGFVLLVAFAP
                     ELIGKRLFEGSNLTFGILAGLLQFIFFWILTLVYVRRANGEFDDINKELVKAAWKEEK
                     "
     gene            3949..4731
                     /locus_tag="P5537_16250"
     CDS             3949..4731
                     /locus_tag="P5537_16250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004364752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase-related protein"
                     /protein_id="HRV79640.1"
                     /translation="MNTRIDLDIDQGIATVTLHNPSKLNAVNAAMWRGLSAAMARIAG
                     DDSVRCVIVRGAGENAFAAGGDIEEFRRVRATVDDALHYHEDLVASALNAIRDCAVPT
                     VAAIRGACVGGGLEIAGCCDIRIAGESARFGAPINRLGFSMYPGEMAGLLALVGPAVV
                     LEILLEGRILDAREALQKGLLTRVVDDERVFEEAAVSAERIRAGAPLVARWHKQWVRR
                     LTTGVPLSEEEKRRAFDFLATEDYREGLAAFSEKRTPVFRGR"
BASE COUNT          855 a         1467 c         1664 g          722 t
ORIGIN      
        1 tcattcggtg gccgcggcag ccggctcgcg ggtcaccagc acctggtcga tgcggtagtt
       61 gtcgatgtcg accacctcga acttgtagcc ggcgtaggtc acgaaatcag tgcgcttggg
      121 caccttgcgc aggcggtaca tgaggaagcc ggcgaccgtc tcgtagttct ggaagccctc
      181 gaagacctcg atctcgagcg cctgcatgac gtcctcgatc ggcgtggcgc cgtcgatgag
      241 ccaggagttg tcgtcgcggc gcacgatgag ctcttcctgg aaggggctga cgaggtcgcc
      301 catcaccgtg ttcatgacgt cctgcagcga cagcaggccc accaccagcg cgtactcgtt
      361 gaggatcagc gcgaaatcct ccttggcgtc gcggaagcgc tcgagcgcct cgaagagcgt
      421 cagcgtgtcg ggcagcatca gcaccttgcg cacgatcggc tgggtgcgca gcgacaggtc
      481 ctggccctgc acgatgcgcg gcaggatgtc cttcgagtcg acatagccga tcacgctgtc
      541 gatgccgtcc tcgcacaccg ggaacttgcc gtgcgggtgc tcggcgatct tgcgccggat
      601 gctctcctcg gattcggaga gcgtgaggaa gacgatgttc tcgcgcgagg tcatcgccga
      661 gggcacgatg cgcgagtcga gctcgaacac gttgctgatc aggtgttgct cctggcgcag
      721 cagcgcgccg gcctgcgcgc cggcgtcggc catggccatg atgtcgtcgg cggtgatgtc
      781 ctcgatgcgc gcgctcggca gcttgaacca gcggaagatg aggttggccg cgccgttgaa
      841 gacccacacc agcggcgcga acagccacat gcacacctgc atcggctgca ccacggccac
      901 cgcgatgcgc tcgggctgca gcatggcgag gcgcttgggc atgaggtcgg cgaagagcac
      961 gaacagcgag gtgacgaaga cgaaggagac gatgaaggcg atcgtgccga gcatcggccc
     1021 gtcgtagacc gtgcgcagga gctcgctgac gtagggtgac agcgcctgct cgccgaccac
     1081 gccgcccagg atggcgaccg cgttgaggcc gatctgcacc acggtgaaga agtggcccgg
     1141 gctgtcctgc agcgcaagca cgcgctgggc gttgaggtgc cctccttcgg ccatcaggcg
     1201 cagcttgatc ttgcgcgagg ccgccagcga gatctcggac atggaaaaga atgcgctcgc
     1261 tgcgatcagc agcagaatga cgagcagttc gttgacaggc acgacgactc ctttgggatg
     1321 aaggtcccgc cggaaggcaa aaccagaatc gaggttcgga gtctaccacc gcgacccgga
     1381 gaccaatcgg cgggcggcgc gggttcgcgc gccattgttc gcgcctgccg gcgctcctac
     1441 gagaggccga gcgcgcgacg gttcgcgtcg cagcaccgga acacgcgatg agcccatgtg
     1501 gagcgcccgg gcacccgacg cgcccannnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1621 nnnnnngaac acgcgatgtt tcatgtagga gcgccggcag gcgcgaaggc ggcggtcgag
     1681 gcccgcggcc acgccaccac cggtcgacaa aaaacccgcc cggcgcgggt gcgcggggcg
     1741 ggctctggat gcggcgcggt tgcgggaacc gcgcggatcg gtcagtgcga cgaggcggtc
     1801 gcggcgccga caccggtctg ggcgcgcacg tactggtcct cgaaggcttc cttctcggcc
     1861 tcggctgcct tgctgctgtc gagggtcgag aacagccagg tcatgaagaa ggcgatcggc
     1921 atcgagaaca gcgccggctg ggtgtagggg aagatcgccg aggcgttgcc cagcacatcc
     1981 acccacaccg acttcgacag cagcacgaac agcaccgcgc tcaccaggcc ggagtagccg
     2041 ccgacgaggg cgcccttggt ggtcagcccc ttccagtaca tcgacaggat cagcaccggg
     2101 aagttggccg aagccgccac gccgaaggcg agcgcgacca tgaacgcgat gttcatcttc
     2161 tcgaaggcca tgccgagcag caccgcaacg atgccgaggc cgatggtggc gaacttcgaa
     2221 accttgagct cggtagcctc gttggccttg cccttcatga tcacgcgcga gtagatgtcg
     2281 tgcgagatcg ccgaagcgcc ggccagcgcc aggcccgcca ccaccgcgag gatggtcgcg
     2341 aaggccaccg ccgacaggaa gccgagcagc aggttgccgc cgaccgcgtt ggccaggtgc
     2401 atggcgatca tgttgccgcc gccgatgacc ttgccgccga tcacgccgcc ctcgaagaac
     2461 tgcgggttct ggccgacgat gatgatcgcg cacaggccca tgatggcgat gacgttgaag
     2521 aagtaggcga cgatgcccga ggcgtagagc acggacttgc gcgcttcctt ggcgtcggtc
     2581 acggtgaaga agcgcatcag gatgtgcggc aggccggcgg taccgaacat caggccgagg
     2641 ccgagcgaga tcgcggtgac cgggtcggcg agcaggctgc cggggttgag cagcttctgg
     2701 ccgagcttgt gcacttccat cgcgcgggtg gtgagttcgt cgaacgagaa gccgaactgg
     2761 ctgaacgcga gcaggccgac cgcggtgccg ccgatcagca gcatgcaagc cttgatgatc
     2821 tgaacccagg tggtggcgac catgccgccg aaggtgacgt acaccatcat cagcgcgccg
     2881 acgacgacga gcgcgatgtt gtagtcgagg ccgaacagca gcttgatgag ctggccggcg
     2941 ccgaccatct gcgcgacgag gtagaagcac accacggtca gcgagctcac cgcggccatc
     3001 gtgcgcacct tgccctggtc gaggcggtag gcggtgatgt cggcgaaggt gaacttgccc
     3061 aggttgcgca ggcgttcggc catcaggaac aggatgatcg gccagccgac gaagaaggac
     3121 agcatgtaga tgtaggcatc cacaccctgc gcgtacatca tcgcggtgag accgagcagc
     3181 gtggcggcgg acatgtagtc gccggcgatc gcgaggccgt tctggaagcc ggtgatgccg
     3241 ccgccggcgg tgtagaagtc ggcggtcgac ttggtgcggc tggcggccca gtaggtgatg
     3301 cccagggtca tcagcacgaa cacgaagaac atgccgatgg cgtggaggtt gagcggctgc
     3361 ttctcggcgg cgtccatcgc ggggccggcg gcgagcacca gcgggctggc ggccagggcg
     3421 agcaggccgg cggcgctgcg ggaaaggcta cgggcggtca ttatttttcc tccttccagg
     3481 cggccttgac gagttccttg ttgatgtcgt cgaactcgcc gttggcacgg cggacgtaca
     3541 ccagggtcag gatccagaag aagatgaact gcagcaggcc cgcgaggatg ccgaaggtca
     3601 ggttgctgcc ctcgaacagg cgcttgccga tgagctcggg tgcgaaggcc acgagcagca
     3661 cgaaaccata gaagacgacc aggacgatcg ccgccagaat gcccgcgaag cgggtgcgct
     3721 tggctacaag ctccgcaaaa cgcgggttgc gccggatgtg cgcgtacatc gagctagaca
     3781 ctttcactcc ctcccaagga taagcgacac gaactgcttt gcctccacct ttcctcctgc
     3841 cccattggcc gtctgacgcg gcatcgaagg cgagcggatg atatatcatc cataagactc
     3901 catacacatc cgtatggaaa aattttattt atagaaaacg ccgaaccgat gaacacaaga
     3961 atcgacctcg acatcgacca gggcatcgcc accgtgaccc tgcacaaccc gtccaagctg
     4021 aacgcggtga atgcggcgat gtggcgcggg ctctcggcag cgatggcgcg catcgcgggc
     4081 gatgattcgg tgcgctgcgt gatcgtgcgc ggcgcgggcg agaacgcctt cgccgcgggc
     4141 ggcgacatcg aggagttccg ccgcgtgcgc gcgacggtgg acgatgcgct gcactatcac
     4201 gaggacctgg tggcgagcgc gctgaacgcg atccgcgact gcgcggtgcc gacggtggcg
     4261 gcgatccgcg gcgcctgcgt cggcggcggg ctggagatcg ccggctgctg cgacatccgc
     4321 atcgcgggcg agtccgcgcg cttcggggcg ccgatcaacc gcctggggtt ctcgatgtat
     4381 ccgggcgaga tggccggact gctcgcgctg gtggggccgg cggtggtgct ggagatcctg
     4441 ctcgagggtc gcatcctcga tgcgcgcgag gcgctgcaaa agggcttgct gacccgcgtg
     4501 gtggatgacg agcgcgtgtt cgaggaggcc gcggtgtcgg ccgagcgcat ccgcgccggc
     4561 gcgccgctgg tcgcgcgctg gcacaagcag tgggtgcgcc ggctgaccac gggcgtgccg
     4621 ctgagcgagg aggagaagcg ccgcgccttc gacttcctcg ccaccgagga ctaccgcgag
     4681 ggcctggcgg cgttcagcga gaagcggacg ccggtgttcc ggggacgtta ggcacgaagc
     4741 ccgggcgccg cggttcgcgc ctgccggcgc tcctacattg gggtggcgct tgctggggcg
     4801 ccacgccc
//
LOCUS       DAOTIN010000187         4790 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_21122_length_4790_cov_7.885533, whole genome shotgun sequence.
ACCESSION   DAOTIN010000187 DAOTIN010000000
VERSION     DAOTIN010000187.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 4790)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4790)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4790
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_21122_length_4790_cov_7.885533"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..165)
                     /locus_tag="P5537_16255"
     CDS             complement(<1..165)
                     /locus_tag="P5537_16255"
                     /inference="COORDINATES: protein motif:HMM:NF012584.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HRV79641.1"
                     /translation="MKIFKLPDLGEGLQEAEIVEWHVKAGDEIAADQPLVSVETAKAI
                     VDIPSPYDGRV"
     gene            complement(162..1142)
                     /locus_tag="P5537_16260"
     CDS             complement(162..1142)
                     /locus_tag="P5537_16260"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HRV79642.1"
                     /translation="MAEINLVEAVNLALAHELARDEAVVLLGEDIGANGGVFRATAGL
                     QQRFGAGRVVDTPLAETAIVGTAIGMAAMGLKPVAEIQFSGFLYPAIDHLVNHAARLR
                     NRTRGRLACPLVVRTPCGGGIHAPEHHSESPEAMLAHTPGLRVVMPSSPARAYGLLLA
                     AIRDPDPVMFLEPTRMYRLFRQEVVDDGEALPLDVCFTLRGGTDLTLVSWGAMLHETQ
                     AAADVLAAEGISAEVIDVATLKPLDLPTILESVARTGRCVIVHEAARTAGLGAEIAAS
                     LAEEGLYSLLAPVQRVTGYDAVMPLSRLEYQYLPSVERIVAAARKTLEAS"
     gene            complement(1135..2238)
                     /gene="pdhA"
                     /locus_tag="P5537_16265"
     CDS             complement(1135..2238)
                     /gene="pdhA"
                     /locus_tag="P5537_16265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045250 - cytosolic pyruvate
                     dehydrogenase complex [Evidence IEA];
                     GO_function: GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HRV79643.1"
                     /translation="MSTVARFQIDHVRFLDPHGEALGPLPDFAHDPARLIPMYRAMYL
                     TRSFDAKAIALQRTGKLGTFASALGQEAIGVGVASAMLPEDALFPSYREHAAQLVRGV
                     RIEESLRYWGGDERGSDFADARHDFPNCVPIGTQVCHAAGAAYAFRLRGEARAAVCFL
                     GDGGSSKGDFYEGLNFAAVWKAPLLIVLSNNQWAISVPRSAQSATATMAQKAIAAGVE
                     GVQVDGNDLVAVHHVAREALAKARAGGGPTLIEAVTYRLGDHTTADDASRYRDPAVVQ
                     EQWSFEPLTRLRNHLVKLGAWGPEKEEALARECADTVNAAVEAYLSTPPPTTAAMFEH
                     LFATLPAALAAQRDEALRFAPRTAGGQPGGDHG"
     gene            complement(2428..3108)
                     /locus_tag="P5537_16270"
     CDS             complement(2428..3108)
                     /locus_tag="P5537_16270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HRV79644.1"
                     /translation="MSTQASDWQVPAATLRWLDAVPAERSVAMLVRHSVRDPLPPGDL
                     GYANALNAEGVELARSLGERLHGRLRSLHTSPLQRCVHTAEVFARVAGDTPPIVTDRM
                     LGDPGAWVLDRALAGENWKRLGSEGIMARLATTDEDLPGTRPARVGAQDLATHMLAIA
                     ASAPGVHVFVTHDILLAIAAARFLGPPPAGPERWPGYLEAAFFWQDEGGLHVAYRDLH
                     RSGLAGAR"
     gene            complement(3124..>4790)
                     /gene="recJ"
                     /locus_tag="P5537_16275"
     CDS             complement(3124..>4790)
                     /gene="recJ"
                     /locus_tag="P5537_16275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008297 - single-stranded DNA
                     exodeoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HRV79645.1"
                     /translation="PQQAFARLADAGLHPLLARLYAARGITRADELDTSLKNLLPPEA
                     LTGTTEAAILLADAIEAGARMVIVADYDCDGATACAVGVRALRAFGADVHYLVPDRVT
                     LGYGLTPAMVEIAARLEPDVLITVDNGIASVEGIAAARTHGMATVITDHHLPGDVLPE
                     ADVIVNPNQPGCDFPSKALAGVGAMFYTMLALRAELRERGAFSGAKEPNLAELLDLVA
                     LGTVADVVKLDRNNRILVAQGLARMRAGRMQAGIRALFGLAGRDPARASTMDLGFMIG
                     PRLNAAGRLSDMSLGIECLITDDAGRAMNIAQELDKLNRERRSIEAGMQEEALNRLAG
                     FDAGNRATVALFEPDWHQGVIGIVAGRIKERLHRPTIAFARANDGELKGSGRSIPGLH
                     LRDALDLVTKRQPDLIVRFGGHAMAAGLTIRESELARFDAAFEEVVSELLEPAQLERR
                     VDTDGSLESGYFALDAARMLDNEIWGQGFPAPVFDDVFRVERQRLLKDKHLKLELSRG
                     STRYEAIRFNHAEGAAGQIHAAFRLGVNEYNGVASVQLMLEHFEAA"
BASE COUNT          611 a         1602 c         1889 g          688 t
ORIGIN      
        1 gacgcggccg tcgtaggggg aggggatgtc cacgatcgcc ttggcggtct cgaccgagac
       61 cagcggctgg tcggcggcga tctcgtcgcc cgccttgacg tgccattcga cgatctcggc
      121 ttcctgcagt ccttcgccca ggtcgggcag cttgaagatc ttcatgacgc ctccagggtc
      181 ttgcgcgccg ccgcgacgat gcgctcgacg ctcggcaggt actggtactc gagccgcgac
      241 agcggcatca cggcgtcgta gccggtcacg cgctgcaccg gcgcgagcag ggaatacagc
      301 ccctcctcgg cgaggctggc ggcgatctcg gcgcccaggc cggcggtgcg cgcggcctcg
      361 tgcacgatca cgcagcgccc ggtgcgcgcg accgactcca ggatggtggg caggtcgagc
      421 ggcttgagcg tggcgacgtc gatgacctcg gccgagatgc cctcggcggc gagcacgtcg
      481 gcggcggcct gggtctcgtg cagcatcgcg ccccagctca ccagggtgag gtcggtgccg
      541 ccgcgcagcg tgaagcacac gtccagcggc aacgcctcgc cgtcgtcgac gacctcctgg
      601 cggaacaggc ggtacatccg cgtgggctcg aggaacatca ccgggtcagg gtcgcggatc
      661 gccgcgagca gcaggccgta ggcgcgcgcg ggcgaggagg gcatgaccac gcgcaggccg
      721 ggggtgtggg cgagcatcgc ctcggggctc tcggagtggt gctcgggcgc gtggatgccg
      781 cccccgcagg gcgtgcgcac caccagcggg caggccagcc ggccgcgcgt gcggttgcgc
      841 aggcgcgcgg cgtggttgac caggtggtcg atcgccggat acaggaagcc ggagaactgg
      901 atctccgcca ccggcttcag gcccatcgcc gccatgccga tcgcggtgcc gacgatcgcg
      961 gtctcggcga gcggggtgtc gaccacccgc ccggcgccga agcgctgctg cagcccggcc
     1021 gtggcgcgga agacgccgcc gttggcgccg atgtcctcgc cgagcagcac gaccgcttcg
     1081 tcgcgcgcca gctcgtgggc gagggccagg ttgaccgcct cgacaaggtt gatctcagcc
     1141 atgatcgcct cccggttgtc cgcccgcggt gcggggcgcg aagcgcaggg cctcgtcgcg
     1201 ctgggccgcg agcgcggcgg gcagggtcgc gaagaggtgc tcgaacatcg ccgcggtggt
     1261 gggcggcggg gtgctcaggt aggcctcgac cgcggcgttc acggtatcgg cgcattcgcg
     1321 cgcgagcgcc tcttccttct ccggccccca ggcgccgagt ttgacgaggt ggttgcgcag
     1381 gcgggtgagc ggctcgaagg accactgctc ctgcaccacc gcggggtcgc ggtagcgtga
     1441 ggcgtcgtcg gcggtggtgt ggtcgccgag tcggtaggtg accgcctcga tcagggtcgg
     1501 accgccgccg gcgcgggcct tggcgagcgc ctcgcgggcg acgtggtgca ccgcgacgag
     1561 gtcgttgccg tcgacctgca ccccctcgac gccggcggcg atcgccttct gcgccatcgt
     1621 ggcggtggcg ctctgcgcgc tgcgcggcac cgagatcgcc cactggttgt tgctgagcac
     1681 gatcagcagc ggcgccttcc acaccgcggc gaagttgagc ccctcgtaga agtcgccctt
     1741 ggagctgcca ccgtcgccga ggaagcacac cgccgcgcgc gcctcgccgc gcagcctgaa
     1801 ggcgtaggcc gcccctgcgg cgtggcagac ctgggtgccg atcggcacgc agttggggaa
     1861 gtcgtggcgg gcgtcggcga agtcgctgcc gcgctcgtcg ccgccccagt agcgcaggct
     1921 ctcctcgatg cgcacgccgc gcacgagctg ggcggcgtgc tcgcggtagg agggaaagag
     1981 cgcgtcttcc gggagcatcg cgctcgccac gccgacaccg atcgcctcct gcccgagcgc
     2041 ggaggcgaag gtgccgagct tgccggtgcg ctgcagcgcg atcgccttgg cgtcgaagct
     2101 gcgcgtgagg tacatcgcgc ggtacatcgg gatcagccgc gcggggtcgt gcgcgaagtc
     2161 gggcagcggc ccgagcgcct cgccatgcgg gtcgaggaaa cgaacgtgat cgatctggaa
     2221 ccgggcgaca gtgctcatgg cgtgctccct tcaggctcgg tcggccccgc atgcctgcgc
     2281 tccccggtcg gggtgggtct cctctgggcg ccggtggcat ccgggcgtgg atgtcgtcgg
     2341 cgaccgggtg gcggcgccgc gacgttgtgc gtttgcgggg ttggagcgcg ggcgtgcgcg
     2401 gatgttcccg agcgcggcgc cgctgggtca gcgcgcgccg gcgaggccgc tgcgatggag
     2461 gtcgcgatag gcgacgtgca ggccgccctc gtcctgccag aagaaggcgg cctcgaggta
     2521 gcccggccag cgctccgggc cggccggcgg cgggccgagg aagcgcgccg ccgcgatcgc
     2581 gagcaggatg tcgtgggtga cgaagacgtg cacgccgggc gcgctggcag cgatcgcgag
     2641 catgtgcgtg gcgaggtcct gtgcgcccac acgcgccggg cgcgtgccag gcaggtcctc
     2701 gtcggtggtc gccaggcgcg ccatgatccc ctcgctgccg aggcgcttcc agttctcgcc
     2761 cgccagcgcg cggtcgagca cccaggcgcc ggggtcgccg agcatgcggt cggtgacgat
     2821 cggtggcgtg tcgccggcca cgcgcgcgaa cacctcggcg gtgtgcacgc agcgctgcag
     2881 cgggctggtg tgcaggctgc gcaggcgtcc gtgcaggcgc tcgccaaggc tgcgcgcgag
     2941 ctcgacgcct tcggcgttga gcgcgttggc gtagccgagg tcgccgggcg gcaaggggtc
     3001 gcgcaccgaa tggcggacca gcatcgccac gctgcgctcg gccggcaccg cgtccagcca
     3061 gcgcagggtg gcggcgggga cctgccagtc ggaggcttgc gtgctcatcg cggcggggcc
     3121 ggtctacgcc gcctcgaaat gctcgagcat cagttgcacg ctggccaccc cgttgtactc
     3181 attgacgccg aggcggaagg cggcgtggat ctggccggcg gcgccctcgg cgtggttgaa
     3241 gcggatggcc tcgtagcgcg tgctgccgcg cgagagctcg agcttgaggt gcttgtcctt
     3301 cagcaggcgc tggcgctcga cgcggaacac gtcgtcgaaa acgggcgccg gaaagccctg
     3361 gccccagatc tcgttgtcga gcatgcgcgc ggcgtcgagc gcgaagtagc cggactcgag
     3421 gctgccgtcg gtgtcgacgc ggcgctcgag ctgggcgggc tcgagcagct cgctcaccac
     3481 ctcctcgaag gcggcgtcga agcgcgcgag ctcggattcg cggatggtga ggccggcggc
     3541 catggcgtgg ccgccgaagc gcacgatgag gtcgggctgg cgcttggtga cgaggtcgag
     3601 cgcgtcgcgc aggtgcaggc cggggatcga gcgcccggag cccttgagct cgccgtcgtt
     3661 ggcgcgcgcg aaggcgatgg tggggcggtg caggcgctcc ttgatgcggc cggcgacgat
     3721 gccgatcacg ccctggtgcc agtcgggctc gaacaacgcg accgtcgcgc ggttgccggc
     3781 gtcgaacccg gccagtcggt tgagcgcctc ttcctgcatg ccggcctcga tgctgcggcg
     3841 ctcgcggttg agcttgtcga gctcctgggc gatgttcatc gcgcgtcccg catcgtcggt
     3901 gatcaggcac tcgatgccca ggctcatgtc ggagagccgg ccggcggcgt tgaggcgcgg
     3961 gccgatcatg aagccgaggt ccatggtgct ggcacgcgcc gggtcgcgcc cggcgagccc
     4021 gaacagggca cggataccgg cctgcatgcg ccccgcgcgc atgcgggcga ggccttgcgc
     4081 gaccaggatg cggttgttgc ggtcgagctt gacgacgtcg gccacggtgc cgagcgcgac
     4141 caggtcgagc agctcggcga ggttgggttc cttggcgccg gaaaaggcgc cgcgctcgcg
     4201 cagctcggcg cgcagggcga gcatggtgta gaacatcgcg cccacgccgg ccagcgcctt
     4261 gctcgggaag tcgcagccgg gctggttggg gttcacgatc acgtcggcct cgggcagcac
     4321 gtcgccgggc agatggtggt cggtgatcac cgtggccatg ccgtgggtgc gcgcggcggc
     4381 gatgccctcg acgctggcga tgccgttatc cacggtgatc agcacgtcgg gctcgaggcg
     4441 cgcggcgatc tcgaccatgg ccggggtgag gccgtagccg agcgtgacgc ggtcgggcac
     4501 caggtaatgc acgtcggcgc cgaaggcgcg tagcgcgcgc acgcccaccg cgcaggcggt
     4561 ggcgccgtcg cagtcgtagt cggcgacgat gaccatgcgc gcgccggcct cgatggcgtc
     4621 ggcgagcagg atcgcggcct cggtggtgcc ggtgagcgcc tcgggcggca gcaggttctt
     4681 caggctggtg tcgagctcgt cggcgcgggt gatgccgcgc gccgcgtaga ggcgggcgag
     4741 caggggatgc aggccggcat cggcgaggcg ggcgaaggct tgctgcggga
//
LOCUS       DAOTIN010000188         4761 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_21278_length_4761_cov_8.080110, whole genome shotgun sequence.
ACCESSION   DAOTIN010000188 DAOTIN010000000
VERSION     DAOTIN010000188.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 4761)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4761)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4761
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_21278_length_4761_cov_8.080110"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..>1237
                     /locus_tag="P5537_16280"
     CDS             <1..>1237
                     /locus_tag="P5537_16280"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: protein motif:HMM:NF019314.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HRV79646.1"
                     /translation="MILDLLQATALLLALCLLQGGLARRCANGGAAFAVGSGLIYGLA
                     CIAGMMMPITLAPGVIVDPRSVVLSMGALFGGPLAGAAAGLAAAAYRLWLGGDGVVIG
                     LTTITLAVLLGLAFRAGAARGWLRPVPLQLFLFGVFTHAVTLLLLAAVPGQTLAGVFA
                     KLGLPYLLLMGAATLLLGALLRDLERHRATERALAASEARLRAITAAIPDLVFVVDED
                     GRYLEVITRQDELLAAPRAQVVGRRFEDVLPAGPAALLRDALEQALASPERASARYAL
                     DTPAGHREFQASAQAIDAPIGGRRAAAILVQDITPNVAAEERIRKLAYYDPLTELPNR
                     RLLVERLGHAIATNARTGRHGALMFIDLDDFKDINDLLGHHNGDQLLREAGARLRGVV
                     RESDTVARFGGDEFVVLLEL"
     assembly_gap    1238..1337
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <1338..1952
                     /locus_tag="P5537_16285"
     CDS             <1338..1952
                     /locus_tag="P5537_16285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HRV79647.1"
                     /translation="REAMALACEELARWVELPGAAGLVMAVNISAAQLYEPGFVEEVL
                     ALLARTGAPAERLKLELTESLLLTDIERAIEAMTRLREMGIRFSIDDFGTGYSSLGYL
                     QRLPLDELKIDRAFVRDLPANASSLAIVRTIMALADTLGIRVIAEGVESSAQHACLLD
                     NGCDAFQGFLFARPEPVESFRARLSASAAREGGAAAQAAAARGR"
     gene            1982..>4761
                     /locus_tag="P5537_16290"
     CDS             1982..>4761
                     /locus_tag="P5537_16290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HRV79648.1"
                     /translation="MNLPPPPPTLPSTSIPAQAGIDFFIDACPFAIIEWSRDLRILRW
                     SPEAERVFGWHAAEVLGKRPDEWRFTHPDDADGVKRAIGQAITRSTPPPPVIGRNYTR
                     DGRLLHCEWHNRANRDADGRLVSLLSFAKDLTLQVRAERALDVSEARYAAIFRNSHAV
                     MLIMDPDSLELVDANPAAEAFYGWPLATLRRMRISDINVLPYERIRAEMQAAREAARF
                     RFDFRHRRADGSIRDVEVYSGPILHESRTLLFSIVHDVSARKEAEATLRKLSSAVEES
                     PESIVITNLAGDIEYVNESFLRKSRYQPEEVLGRNPRILQSGKTPRSTYEDMWRSLAA
                     GQAWTGVLHNRNKDGEECYERAHIVPIHDNAGKPTHYVAIKEDITAARRMEAELHDYR
                     ERLEHLVETRTRELSEALAAAEAANRAKSDFLATMSHEIRTPMNGVAGLVDVLAHSGL
                     DDEQAEVVDIMRDSAATLLHLIDDILDFSKIESGHLELDLHPASLVELVERVGDTLQP
                     VAKKRGVTLEVFVDPDLPGQVLTDGLRVQQILTNLAGNAIKFSSGEGRSGRVDLRASR
                     SADGRLAFSVRDNGIGMSAEVVQRLFQPFSQAETSTTRRFGGTGLGLAISRRLADLLG
                     GEITVDSRPGAGACFTLALALEPVRADEHPRSQALAGVLCILAIADSRLVADWGSYLA
                     HAGARVKRAPGSEQALQFLAAAGHEAVLLVDRPLAPTAHARWQQLPPPRRPGILLILH
                     GARRQARQQGPGLFTLDREGVHRDELIRAVAVACGRDAAEWACGPTQRRGASAVAGLD
                     PRMAAARILVAEDNDINRKVITRQLGLLGLSCELAEDGQEALARWREGPYDLLLTDLH
                     MPNMDGYTLAARIRAEEDPRRRLAIVAVTANALRGEDRRCLDAGMDDYLVKPVQIEAL
                     RAVLERHLPAATP"
BASE COUNT          657 a         1848 c         1542 g          614 t
ORIGIN      
        1 agatgatcct cgacctgctc caggcgaccg ccctgctgct cgccctctgc ctgctgcagg
       61 gcggactggc gcggcggtgc gcgaatggcg gcgcggcctt cgcggtgggc tccgggctga
      121 tctacggcct cgcctgcatc gccggcatga tgatgccgat cacgctggcc cccggcgtca
      181 tcgtcgatcc gcgctcggtg gtgctgagca tgggcgccct cttcggcggc ccgctcgccg
      241 gcgccgcggc tggcctcgcc gccgcagcct accgcctgtg gctgggaggc gacggcgtgg
      301 tgatcggcct cacgacgatc acgctggcgg tgctgctcgg cctcgccttc cgcgcaggcg
      361 cggcacgcgg ctggctacgc ccggtgccgc tgcaactctt cctcttcggc gtgttcaccc
      421 atgccgtcac gctgctgctg ctggccgccg tgccgggcca gaccctcgcc ggggtgttcg
      481 ccaagctcgg cctgccctac ctgctgctga tgggcgccgc cacgctgctg ctcggcgccc
      541 tgctgcgcga cctcgagcgc caccgcgcga ccgaacgcgc gctggcggcg agcgaggcgc
      601 gcctgcgcgc gatcaccgcg gccatccccg acctggtctt cgtggtcgac gaggacggcc
      661 gctacctcga ggtcatcacc cgccaggacg agctgctcgc cgcaccgcgc gcgcaggtgg
      721 tcggccggcg cttcgaggac gtcctccccg cagggccggc cgcgctgctg cgcgacgcgc
      781 tggagcaggc cctggccagc cccgagcgtg ccagcgcccg ctatgcgctc gacacgcccg
      841 ccggccatcg cgagttccag gcctcggcgc aggccatcga cgccccgatc ggcggacgcc
      901 gcgccgcggc catcctcgtg caggacatca ctcccaacgt ggccgcggag gagcgcatcc
      961 gcaagctcgc ctactacgac ccgctcaccg agctgcccaa ccgccgcctg ctcgtcgagc
     1021 gcctcggcca cgcgatcgcc accaacgccc gcacgggccg ccacggcgcg ctgatgttca
     1081 tcgacctcga cgacttcaag gacatcaacg atctgctcgg ccaccacaac ggcgaccagc
     1141 tgctgcgcga ggccggcgcg cgcctgcgcg gcgtggtgcg cgagtccgac acggtggcgc
     1201 gcttcggcgg cgacgagttc gtggtcctgc tcgagctnnn nnnnnnnnnn nnnnnnnnnn
     1261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1321 nnnnnnnnnn nnnnnnncgc gaggcgatgg cgctcgcctg cgaggagctg gcgcgctggg
     1381 tcgagctgcc cggcgccgcg ggcctggtga tggcggtcaa catcagcgca gcccagctct
     1441 acgagcccgg cttcgtcgag gaggtcctcg ccctgctggc gcgcaccggg gcccccgccg
     1501 aacggctcaa gctcgagctc accgagtcgc tgctgctcac cgacatcgag cgcgcgatcg
     1561 aggccatgac ccgcctgcgc gagatgggca tccgcttctc gatcgacgac ttcggcaccg
     1621 gctactcctc gctcggctac ctgcagcgcc tgccgctcga cgagctcaag atcgaccgcg
     1681 ccttcgtgcg cgacctgccc gccaacgcca gcagcctggc gatcgtgcgc accatcatgg
     1741 cgctcgccga caccctcggg atccgcgtca tcgccgaggg cgtggagagc tccgcccagc
     1801 acgcctgcct gctcgacaac ggctgcgacg ccttccaggg cttcctgttc gcccgccccg
     1861 agccggtgga gagcttccgc gcacgcctgt ccgcaagcgc ggcgcgcgag ggcggcgcag
     1921 cggctcaagc cgcagccgct cgcggccgat gaacgatcat cgcccgagcc ctgccgccac
     1981 cgtgaacctc ccccctccgc ccccgacgct gccatcgacg tccatcccgg cccaggccgg
     2041 aatcgacttc ttcatcgacg cctgcccgtt cgcgatcatc gagtggagcc gcgacctgcg
     2101 catcctgcgc tggtcgcccg aggccgagcg ggtgttcggc tggcacgccg ccgaagtgct
     2161 gggcaagcgc ccggacgagt ggcgcttcac ccaccccgac gacgcggacg gggtcaagcg
     2221 cgcgatcggc caggcgatca cccgcagcac gccgccgccg ccggtgatcg gccgcaacta
     2281 cacccgcgac ggccgcctgc tgcactgcga gtggcacaac cgcgccaacc gcgacgccga
     2341 cggccggctg gtgtcgctgc tgtccttcgc caaggacctc accctgcagg tccgcgccga
     2401 gcgcgcgctc gacgtcagcg aggcgcgcta cgcggcgatc ttccgcaaca gccacgccgt
     2461 gatgctgatc atggaccccg acagcctgga gctcgtcgat gccaacccgg ccgccgaggc
     2521 cttctacggc tggccgctcg cgaccttgcg gcgcatgcgc atcagcgaca tcaacgtcct
     2581 cccctacgag cgcatccgcg ccgagatgca ggcggcccgc gaagccgcac gctttcgctt
     2641 cgacttccgc caccgccgcg ccgacggctc catccgcgac gtcgaggtct acagcgggcc
     2701 catcctgcac gagtcgcgca ccctgctgtt ctccatcgtt cacgacgtga gcgcgcgcaa
     2761 ggaggccgag gcgaccctgc gcaagctctc cagcgcggtc gaggagagcc cggagagcat
     2821 cgtcatcacc aacctcgccg gcgacatcga gtatgtgaac gagagcttcc tgcgcaagag
     2881 ccgctaccag cccgaagagg tgctgggccg gaacccgcgc atcctgcagt cgggcaagac
     2941 gccgcgcagc acctacgagg acatgtggcg cagcctggcc gcgggccagg cgtggaccgg
     3001 cgtgctgcac aaccgcaaca aggacggcga ggaatgctac gagcgcgccc acatcgtccc
     3061 gatccacgac aacgccggca agcccaccca ctacgtcgcg atcaaggagg acatcaccgc
     3121 cgcgcgccgc atggaggcgg agctgcacga ctaccgcgag cgcctcgagc acctggtcga
     3181 gacccgcacg cgcgagctga gcgaggcgct cgccgccgcc gaggccgcca accgcgccaa
     3241 gagcgacttc ctcgccacca tgagccacga gatccgcacc cccatgaacg gcgtggccgg
     3301 cctggtcgac gtgctcgccc acagcgggct ggacgacgag caggccgagg tggtcgatat
     3361 catgcgcgac tccgcggcga ccctgctcca tctcatcgac gacatcctcg acttctccaa
     3421 gatcgagtcc ggccacctcg agctcgacct gcacccggcc agcctggtcg agctcgtcga
     3481 gcgcgtcggc gacaccctgc agccggtggc gaagaagcgc ggcgtcaccc tcgaggtctt
     3541 cgtcgacccc gacctccccg ggcaggtgct gaccgacggg ctgcgcgtac agcagatcct
     3601 caccaacctc gccggcaacg cgatcaagtt ctcctccggc gagggtcgca gcggccgggt
     3661 cgacctccgc gccagccgca gcgcggatgg ccgcttggcg ttctcggtgc gcgacaacgg
     3721 catcggcatg agcgcggagg tggtccagcg cctgttccag cccttctccc aggccgagac
     3781 ctccacgacc cgacgcttcg gcggcaccgg cctcgggctg gcgatcagcc gccgcctggc
     3841 cgacctgctc ggcggcgaga tcacggtcga cagccgcccc ggcgcgggcg cctgcttcac
     3901 cctggcgctg gcgctcgagc ccgtgcgcgc ggacgagcac ccgcgatcgc aggcgctcgc
     3961 cggcgtgctg tgcatcctgg cgatcgccga ctcgcgcctg gtcgccgact ggggcagcta
     4021 cctcgcgcac gccggcgcgc gcgtgaagcg cgcgcccggc agcgagcagg cgctgcagtt
     4081 cctcgccgcg gccgggcacg aggccgtgct gctcgtcgac cggccgctgg cgccgacggc
     4141 acacgcgcgc tggcaacagc ttcccccgcc gcgccgcccc ggcatcctgc tcatcctgca
     4201 tggcgcgcgc cgccaggcac gccagcaggg ccccggcctg ttcacgctcg accgcgaagg
     4261 cgtgcaccgc gacgagctga tccgcgcggt ggccgtcgcc tgcgggcgcg acgccgccga
     4321 atgggcgtgc gggccgacgc agcgccgcgg cgcgtccgca gtcgccgggc tcgatccgcg
     4381 catggcggcc gcacgcatcc tcgtcgccga ggacaacgac atcaaccgca aggtcatcac
     4441 ccgccagctc ggtctgctcg ggttgtcctg cgagctggcc gaggacggcc aggaggcgct
     4501 cgcgcgctgg cgcgaaggcc cctacgacct gctgctgacc gacctccaca tgcccaacat
     4561 ggacggctac acgctggccg cacgcatccg cgcggaggag gacccgcgcc ggcgcctggc
     4621 catcgtcgcg gtcaccgcca acgccctgcg cggcgaagac cggcgctgtc tcgacgccgg
     4681 catggacgac tacctcgtca agccggtgca gatcgaggcc ttgcgtgcgg tgctggagcg
     4741 ccacctcccg gccgccaccc c
//
LOCUS       DAOTIN010000189         4732 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_21460_length_4732_cov_4.556340, whole genome shotgun sequence.
ACCESSION   DAOTIN010000189 DAOTIN010000000
VERSION     DAOTIN010000189.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 4732)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4732)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4732
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_21460_length_4732_cov_4.556340"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            47..1639
                     /gene="peaA"
                     /locus_tag="P5537_16295"
     CDS             47..1639
                     /gene="peaA"
                     /locus_tag="P5537_16295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA];
                     GO_function: GO:0030058 - amine dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0009310 - amine catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quinohemoprotein amine dehydrogenase subunit
                     alpha"
                     /protein_id="HRV79649.1"
                     /translation="MENETNIGSKVAAGLLALAAAFGAPAPAGAAEGPALLAANCLSC
                     HSAQGSGISRVEGQRKSPEGWQMTITRMQEQHGARISPEDKRRLIKYLADTRGLAPTE
                     TAGWRYLLEHDNNRVEAIDERYRDLCARCHSGARFALQRRSEDEWKLLMHTHIGLNPT
                     LEFHSLARDRQWFQLAVNEVAPALARDFALDARAWKTWQAAPRVVLGGSWRITGYLPG
                     KGAFEGRMRATAAGADRFELAIEGRYADGAPLSGRGVATVYTGYEWRGSVDIDGIALR
                     QVMAADARGERMQGRQHLADSRRMGGELSALREGAAPMVMAVMPAQLRRGETAELTVV
                     GSGLSGAVSLGKGVRVLEVVSRSADRVMLRARAEGRDGLADVVVGTARGKGLLAVYDR
                     VARVEVEPANAIARVGGPGDAQMEKVGVAYRAVGWAAGRDGKPGTADDLRLGYLRAQW
                     SIEPADEEADKARDQDFVGRIGADGVFVPGDAGPNPARPKSLGNTGRVNVVAVVDQAG
                     GRVEGRGKLDVAVPDFVHRALD"
     gene            1656..3089
                     /gene="peaB"
                     /locus_tag="P5537_16300"
     CDS             1656..3089
                     /gene="peaB"
                     /locus_tag="P5537_16300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quinohemoprotein amine dehydrogenase maturation
                     protein"
                     /protein_id="HRV79650.1"
                     /translation="MTTLTLIRPNLHRVDSAGRQMLFHVPSSSLFELDGAARDVLALF
                     DEHATLDAASLAERLGGRHDALAVRETVDELRQLQVLAVEGEDGRINPPAGEVTRFPL
                     DTLVLNVNTGCNLSCTYCYKEDLSAPAKGLRMSLETATKAIEMMLAESPGKPIYTIVF
                     FGGEPLSNMGLIRAVVDFAERRFAEAGARVDFTLTTNATLLTAEIIDWLDAHRVGITV
                     SMDGPPAVHDRNRRTFGGDGTYDVVRRKVDLLLARYRARPVGCRVTLTRGITGVVPIF
                     EHLHHEVGFAEVGFGPVTSGDIQAFNLTADELAEVFAGLKALGRRYLDAALRNRSLGF
                     GNLHQLMTDLHEGNKKSLPCGAGVGLLAVDGKGGLNLCHRFTGSALPTFGDVDAGIDR
                     ARLGAFVGRRLERSGTGCATCRIRNICSGGCYHESYAKYGDAAAPSYHYCELLRDWID
                     FGIETYARIVTENPGFFAAHVSPRRTA"
     gene            3086..3412
                     /gene="qhpC"
                     /locus_tag="P5537_16305"
     CDS             3086..3412
                     /gene="qhpC"
                     /locus_tag="P5537_16305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004360680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinohemoprotein amine dehydrogenase subunit
                     gamma"
                     /protein_id="HRV79651.1"
                     /translation="MKHLKSLNKKAQRLDAAEGKPEAIEEVVAMQTVVGCTATTDPGW
                     EIDAFGGATSLCQPMEADLYGCADSCWWPAQVPDTMSHYPDWGDGKADATRDWRKLDG
                     IFEDKI"
     gene            3413..4558
                     /gene="peaD"
                     /locus_tag="P5537_16310"
     CDS             3413..4558
                     /gene="peaD"
                     /locus_tag="P5537_16310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA];
                     GO_function: GO:0030058 - amine dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0009310 - amine catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quinohemoprotein amine dehydrogenase subunit
                     beta"
                     /protein_id="HRV79652.1"
                     /translation="MGAILMSLIPKLRDLRAAALLAAAALATACATPAQKSATADAEY
                     LLTVTRPGLLHVIDMKTNRIARSCELPGKFGSGALVPAPDGRHAFVLGNLWEDVYGFE
                     LETCKLVFSARQSEGDVTVKTVQSLAVSADGSELYTVQNPVRRGADRFEVQPPRLAVY
                     RIADGLDAKPVRSFPVKRRITKIAATAGGEVILGGADVEAIDVRSGAVRTVSALANWD
                     RGPGWLTPDAFAMHSQGEHLNEYVMPYVTAKFADDKQDMANAEWWWGMSRVDLATGKA
                     ETREIFPFEFVIFSLVADPRDRNILYGAFNTLSKHDIAKRETLKVVELDHTYYSLQLS
                     RDATRVYVGGAGSTISIHDSGTLEKIGTIQLPGDMSTADVRVAWLRP"
BASE COUNT          729 a         1654 c         1683 g          666 t
ORIGIN      
        1 ggcacccgcc cgggccgcat gcgcaacgga gcgaggagcg agggccttgg aaaacgaaac
       61 gaacatcggg tcgaaggtcg cggcggggtt gcttgccctg gcggccgcgt tcggcgcacc
      121 ggcgcctgcg ggggcggcgg agggaccggc gctgctggcc gcgaactgtc tttcctgcca
      181 tagcgcgcag ggcagcggca tttcccgcgt cgagggccag cgcaagagcc ccgaaggctg
      241 gcagatgacg atcacgcgga tgcaggagca gcacggcgcc cggatctcgc ccgaagacaa
      301 gcgccgcctg atcaagtacc tggctgacac gcgcgggctg gcgccgaccg agaccgcggg
      361 ctggcgctac ctgctcgaac acgacaacaa ccgcgtcgag gccatcgacg agcgttaccg
      421 cgacctgtgt gcacgctgcc actccggtgc ccgcttcgcg ctccagcgcc gcagcgagga
      481 cgagtggaag ctgctgatgc acacccacat cggcctcaac ccgacgctcg agttccactc
      541 gctggcgcgc gatcggcagt ggttccagct cgcggtgaac gaggtcgctc ccgcgctggc
      601 gcgcgacttc gcgctcgatg cgcgcgcctg gaagacgtgg caggctgcgc cacgggtcgt
      661 gctcggcggc agctggcgga tcaccggcta cctgcccggc aagggcgcgt tcgaaggacg
      721 catgcgcgcg accgcggccg gtgcggaccg cttcgagctc gcgatcgagg ggcgctatgc
      781 cgacggcgcc ccgctctcgg gccgtggcgt ggccactgta tataccggct acgaatggcg
      841 cggcagcgtc gacatcgacg gcatcgcgct gcgccaggtg atggcggccg atgcgcgcgg
      901 cgagcgcatg caggggcgcc agcacctcgc cgactcgcgc cgcatgggcg gggagctgag
      961 cgcgctgcgc gagggcgccg cgcccatggt gatggcggtg atgcccgcgc agctgcgccg
     1021 cggcgagacc gccgaactca ccgtggtcgg cagtggcctg tcgggtgcgg tgtcgctcgg
     1081 caagggcgtg cgcgtgctcg aggtggtctc gcgcagcgcc gaccgcgtga tgctgcgggc
     1141 gcgtgccgaa ggtcgcgacg gcctcgcgga cgtggtggtc ggcacggcgc gcggcaaggg
     1201 cctgctcgcg gtgtacgatc gtgtcgcgcg cgtcgaggtc gagccggcca acgcgatcgc
     1261 gcgcgtgggc gggccgggcg atgcacagat ggagaaggtc ggcgtcgcct accgcgccgt
     1321 cggctgggcg gccggtcgcg acggcaagcc gggcaccgcc gacgacctgc gcctcggcta
     1381 cctgcgggcg cagtggtcga tcgagcccgc cgacgaggag gccgacaagg cgcgcgacca
     1441 ggacttcgtc ggccgcatcg gcgccgatgg cgtgttcgtc ccgggcgacg ccgggccgaa
     1501 tccggcgcgg ccgaagtcgc tcggcaacac cgggcgggtg aacgtggtcg ccgtggtgga
     1561 tcaggccggc ggccgggtcg agggccgcgg caagctcgac gtcgccgtgc ccgacttcgt
     1621 gcaccgtgcg ctcgactgaa tgcggggcag atccgatgac gaccctgacc ctgatccggc
     1681 ccaacctgca tcgcgtcgac agcgcgggcc ggcagatgct gttccatgtg ccgagcagca
     1741 gcctgttcga actcgacggc gccgcgcgcg acgtgctggc gctgttcgac gagcacgcca
     1801 cgctcgatgc cgcgagcctc gccgagcgtc tcggcggtcg ccacgacgcg ctcgccgtgc
     1861 gcgagaccgt ggatgagctg cgccagctcc aggtgctggc cgtggagggc gaggacggcc
     1921 gcatcaaccc gcctgcgggc gaggtgacgc gctttcccct tgacaccctg gtgctcaacg
     1981 tcaatacggg ctgcaacctg agctgcacct attgctacaa ggaagacctc agcgcgccgg
     2041 cgaagggcct gcgcatgagc ctggagaccg cgaccaaggc gatcgagatg atgctcgccg
     2101 agtcgccggg caagccgata tacaccatcg tcttcttcgg cggcgagccc ctgtcgaaca
     2161 tggggctgat ccgcgcggtg gtcgacttcg ccgagcgccg cttcgccgag gccggcgcgc
     2221 gcgtggattt caccctcacc accaacgcca ccctgctcac cgccgagatc atcgactggc
     2281 tggacgcgca ccgggtcggc atcaccgtgt cgatggacgg gccgcccgcg gtgcatgacc
     2341 gcaaccggcg caccttcggc ggcgacggta cctatgacgt ggtgcggcgc aaggtcgacc
     2401 tgctgctggc gcgctatcgt gcgcgcccgg tcggctgccg cgtcaccctc acccgcggca
     2461 tcaccggcgt ggtgccgatc ttcgagcacc tgcaccacga ggtcggcttc gccgaggtgg
     2521 gcttcggtcc ggtgacctcg ggcgacatcc aggccttcaa cctcaccgcc gacgaactcg
     2581 ctgaggtttt cgcgggcctg aaggcgctcg ggcgccgcta tctcgacgca gcgctgcgca
     2641 accgcagcct cggcttcggc aacctgcacc aactgatgac cgacctgcac gagggcaaca
     2701 agaagagcct gccctgcggc gccggggtcg gcctgctcgc ggtcgacggc aagggcgggc
     2761 tcaacctctg ccaccgtttc accggctccg cgctgcccac cttcggcgac gtcgacgccg
     2821 gcatcgaccg cgcccgcctg ggcgccttcg tcgggcgccg gctggagcgc agcggcaccg
     2881 gctgcgcgac ctgccgcatc cgcaatatct gttcgggtgg ctgctaccac gagagctatg
     2941 cgaagtacgg cgacgccgcc gcgccttcct accactactg cgagctgctg cgcgactgga
     3001 tcgacttcgg catcgagacc tacgcgcgca tcgtcaccga gaaccccggc tttttcgccg
     3061 cacacgtttc cccgcggagg accgcatgaa gcacctgaag tcgctcaaca agaaggcgca
     3121 gcgcctggac gccgcggagg gcaagcccga ggcgatcgag gaggtcgtcg ccatgcagac
     3181 ggtggtcggc tgcaccgcga ccaccgaccc gggctgggag atcgacgcct tcggcggcgc
     3241 cacctcgctg tgccagccga tggaggccga cctctacggc tgcgccgatt cgtgctggtg
     3301 gccggcgcag gtgcccgaca ccatgagcca ctaccccgac tggggcgacg gcaaggccga
     3361 tgcgaccagg gactggcgca agctggacgg catcttcgag gacaagatct gaatgggagc
     3421 gatcctcatg agcctcatcc ccaaactgcg cgacctgcgt gcggctgccc tgcttgccgc
     3481 cgcggcgctg gcgacggcgt gcgcgacccc ggcgcagaag tccgcgacgg ccgacgcgga
     3541 gtacctgctc acggtcaccc gacccggcct actccacgtc atcgacatga agaccaaccg
     3601 catcgcgcgc agctgcgagc tccccggcaa gttcggctcg ggcgcgctgg tgccggcacc
     3661 cgacggtcgc cacgccttcg tgctcggcaa cctgtgggag gacgtctacg gtttcgagct
     3721 ggagacctgc aagttggtgt tctcggcccg gcagtcggaa ggcgacgtca ccgtcaagac
     3781 ggtgcagtcg ctcgcggtga gcgcggacgg cagcgagctc tacaccgtgc agaatccggt
     3841 gcgccgcggc gcagaccgct tcgaggtgca gccgccgcgt ctcgcggtgt atcgcatcgc
     3901 cgacggcttg gacgccaagc cggtgcgcag cttcccggtc aagcgccgca tcaccaagat
     3961 cgccgccacc gcgggcggcg aggtcatcct gggcggggcc gacgtcgagg cgatcgacgt
     4021 gcgcagcggc gccgtgcgca cggtctcggc gctggcgaac tgggaccgcg gtccgggctg
     4081 gctgacgccg gatgcgttcg cgatgcactc gcagggtgag cacctgaacg agtacgtgat
     4141 gccctacgtg accgcgaagt tcgccgatga caagcaggac atggcgaacg ccgagtggtg
     4201 gtggggcatg agccgggtgg acctcgccac cggcaaggcc gagacgcgcg agatcttccc
     4261 cttcgagttc gtgatcttct cgctggtggc cgacccgcgc gatcgcaaca tcctgtacgg
     4321 cgccttcaac acgctgtcga agcacgacat cgcgaagcgc gagacgctga aggtggtcga
     4381 gctcgaccac acctactaca gcctgcagct gtcgcgcgac gccacgcgcg tctacgtggg
     4441 cggggcgggc agcacgatca gcatccacga cagcggcacg ctggagaaga tcggcacgat
     4501 ccagctcccc ggcgacatgt ccaccgcgga cgtgcgcgtg gcctggctgc ggccctagcg
     4561 acacccggtt cggctggcgc cgggcgtagg tccatactat atgttcagca ggagccggcc
     4621 gctgcggcgg ccggattgcg tgaacgctgc ccgttgtgac gggctgaggc tacatccggg
     4681 aggactccgc catgacccga acgcccaagg tgtgcttcga ccgcgtactg cc
//
LOCUS       DAOTIN010000190         4616 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_22166_length_4616_cov_8.571804, whole genome shotgun sequence.
ACCESSION   DAOTIN010000190 DAOTIN010000000
VERSION     DAOTIN010000190.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 4616)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4616)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4616
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_22166_length_4616_cov_8.571804"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..696
                     /locus_tag="P5537_16315"
     CDS             <1..696
                     /locus_tag="P5537_16315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory protein FdhE"
                     /protein_id="HRV79653.1"
                     /translation="EDVLARARKHRMPPISVASYQRPAVWREILRNIVGDLLENAPVG
                     ARETLDGLLVTSAEDLDKLGEKLLNGEPEGADMVRLPYVAAAMQVVFTALASKLDADA
                     LPLMEAHSTCPVCGSHPVVSVIRSDGPTAGLRYVHCTLCNTEWHVPHATCVSCGDRDK
                     ITLHEIDGDDGIARAESCGSCESYTKLIVQPKNVRVDPIADDLASVALDMLVDDAGFV
                     RSGPNYLLIGAGE"
     gene            complement(783..1085)
                     /locus_tag="P5537_16320"
                     /pseudo
     CDS             complement(783..1085)
                     /locus_tag="P5537_16320"
                     /inference="COORDINATES: protein motif:HMM:NF027439.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003860 - 3-hydroxyisobutyryl-CoA
                     hydrolase activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
     gene            complement(1105..3309)
                     /locus_tag="P5537_16325"
     CDS             complement(1105..3309)
                     /locus_tag="P5537_16325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004383721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC domain/YcaO domain-containing protein"
                     /protein_id="HRV79654.1"
                     /translation="MEIKVNFLDKLRLEAKFDDFTVIADQPIRYKGDGSAPGPFDYFL
                     ASSALCAAYFVKLYCETRNIPTENIRLSQNNIVDPENRYKQIFKIQVELPEDISAKDR
                     QGILRSIERCTVKKVVQTGPEFVVEEVADLDADAQALLALDPDTGTRTYIAGKDLPLE
                     QTIANMSRFLADLGIKIEIASWRNLVPNVWSLHIRDAHSPMCFTNGKGASKESALASA
                     LGEYIERLNCNHFYNDQFWGEDIGDAPFVHYPNERWFKPGRKDALPAGLLDDYCLAIY
                     DPEGELRASHLYDTNSGNVARGICALPYVRQSDGEVVYFPTNLIDNLYLSNGMSAGNT
                     LPEAQVQCLSEIFERAVKREILEGELALPDVPPEVLAKYPAIVAGIEGLEAQGFPVLV
                     KDASLGGKYPVMCVTLMNPRTGGVFASFGAHPSLEVALERSLTELLQGRSFEGLNDLP
                     APTFESNAVTEPNNFVEHFIDSSGVVSWRFFSARADHPFVEWDFSGHGERSNVDEAAT
                     LFGILEDMGKEAYMAVFDQLGAKVCRIVVPGYSEVYPVDDLIWNNTNKALAFRADILD
                     LHRLDDEALEALLDRLEESELDDYTDIIELIGIEFDENTVWGQLTILELKLLIHLALQ
                     QLEEAKERVEALLQYNDNTVERVLFYQALNVVLEVMLDDELELADYEANFRRMFGDAR
                     MDAVIGSVEGSVRFHGLTPTSMKLEGLDRHQRLIDSYRKLHKARARAAGVSA"
     gene            complement(3597..4112)
                     /locus_tag="P5537_16330"
     CDS             complement(3597..4112)
                     /locus_tag="P5537_16330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79655.1"
                     /translation="MSRLSTESVEKAVDAVQAMDRAQKERLADEIFRMQPNMLGSILV
                     LPRLGVPMEKVEFAVGVLLVCFQAMKESGLAWPVITEDEQERQLARFVAATRLGEDIT
                     PSLRSRALRRYISAHPEKSLAAYVASDTSKWLGEIAADESDKYAMLAVWNLVNCIAFA
                     ELPRSKRTKPT"
BASE COUNT          739 a         1533 c         1582 g          762 t
ORIGIN      
        1 gaagacgtgc tcgcgcgcgc gcgcaagcac cgcatgccgc cgatcagcgt ggcctcgtac
       61 cagcgccccg cggtgtggcg cgagatcctg cgcaacatcg tcggcgacct gctggagaac
      121 gccccggtcg gcgcgcgcga gacgctcgac gggctgctcg tgaccagcgc cgaggacctc
      181 gacaagctcg gcgagaagct gctcaacggc gaacccgagg gtgccgacat ggtccgcctg
      241 ccctacgtcg ccgcggcgat gcaggtggtg ttcaccgcgc tcgccagcaa gctcgacgcc
      301 gacgcgctgc cgctgatgga agcccacagc acctgcccgg tgtgcggcag tcatccggtg
      361 gtgagcgtga tccgcagcga cggcccgacc gccggcctgc gctacgtgca ttgcacgctg
      421 tgcaacaccg agtggcacgt cccgcacgcc acctgcgtga gctgcggcga ccgcgacaag
      481 atcaccctgc acgagatcga cggcgacgac ggcatcgccc gcgcggagtc ctgcgggtcg
      541 tgcgagagct acaccaagct catcgtccag ccgaagaacg tccgcgtcga cccgatcgcc
      601 gacgacctcg cctcggtggc gctggacatg ctggtagacg acgccggctt cgtgcgcagc
      661 gggccgaatt acctgctgat cggcgcgggg gagtaagcgg atcaccgcca aggggcgcgg
      721 agctcgagca cgggttcgcg cctgccggcg ctcctacagg aggtggctgg cgtcgctcac
      781 catcaccgcg cgccgttcaa tgcaggaggc cggaaggcgc gaaggcggcg gggcggaccg
      841 tgcgggccgt gtcggagcat gcgcaggttc gcgcctgccg gcgctcctac agggggttgc
      901 cggcgaagaa ggcctccacc tgctcgcgcc gcacctccgc caccgcgcgg agccgccagc
      961 gcgatggtgg gcttggggta agggtggatg cggcagtcga gcgcggactc cccgtcgaag
     1021 aagtgcccga gttcgggcga gccctggcgc tgcagctggt acaccgagcg cacgtcgcca
     1081 ccggcgcgga acgcgctcgc aaatctacgc ggacaccccc gccgcgcgcg cccgcgcctt
     1141 gtgcagcttg cggtagctgt cgatgaggcg ctggtggcgg tcgagcccct cgagcttcat
     1201 gctcgtcggc gtgaggccgt ggaagcgcac gctgccttcc accgagccga tcaccgcgtc
     1261 catgcgcgca tcgccgaaca tgcggcggaa gttggcctcg tagtcggcca gttccagctc
     1321 gtcgtccagc atcacctcca gcaccacgtt gagcgcctgg tagaacagca cgcgctcgac
     1381 cgtgttgtcg ttgtattgca gcaaggcctc cacgcgctcc ttcgcctcct caagctgctg
     1441 cagggcgaga tggatcagca gcttcagctc caggatcgtg agctggcccc acacggtgtt
     1501 ctcgtcgaac tcgatgccga tcagctcgat gatgtcggtg taatcgtcga gctcgctctc
     1561 ttccaggcga tcgagcaggg cttcgagggc ctcgtcgtcg aggcggtgca ggtcgaggat
     1621 gtcggcgcgg aaggccagcg ccttgttggt gttgttccag atcaggtcat cgacgggata
     1681 gacctcggaa tatcccggca cgacgatgcg gcagaccttg gcgccgagct ggtcgaacac
     1741 cgccatgtac gcttccttgc ccatgtcctc gaggatgccg aacagggtgg cggcctcgtc
     1801 aacgttggat cgttcgccgt ggccggagaa gtcccattcg acgaagggat gatcggcccg
     1861 ggcactgaag aagcgccacg acaccacgcc gctggagtcg atgaagtgct cgacgaagtt
     1921 gttcggctcg gtcaccgcgt tgctctcgaa ggtcggcgcc ggaaggtcgt tgaggccttc
     1981 gaagctgcgc ccctgcagca gctcggtgag gctgcgctcc agcgccacct cgaggctcgg
     2041 gtgcgccccg aaggaggcga acacgccgcc ggtgcgcggg ttcataagcg tcacgcacat
     2101 caccgggtac ttgccaccca gcgacgcgtc cttcaccagc accggaaagc cctgcgcctc
     2161 cagcccttcg atgccggcca cgatggcggg atacttcgcc agcacctccg gcggcacgtc
     2221 gggcagggca agctcgcctt cgaggatctc gcgcttcacc gcgcgctcga agatctcgga
     2281 caggcactgc acctgcgcct cgggcagcgt gttgccggcg ctcatgccgt tgctgaggta
     2341 gaggttgtcg atcaggttgg tggggaaata caccacctcg ccgtcggact ggcgcacata
     2401 gggcagcgcg cagatgccgc gcgccacgtt gccggagttg gtgtcgtaca gatgcgaggc
     2461 gcgcagctcg ccctcggggt cgtagatcgc caggcagtag tcgtcgagca gcccggccgg
     2521 cagcgcatcc ttgcggccgg gcttgaacca gcgctcgttc gggtaatgca cgaagggggc
     2581 gtcgccgatg tcctcgcccc agaactggtc gttgtagaag tgattgcagt tgaggcgctc
     2641 gatgtactcg cccagggccg aggccagcgc gctctccttg ctcgcgccct tgccgttggt
     2701 gaagcacatc ggcgaatgcg catcgcggat gtgcagcgac cacacgttgg gcaccaggtt
     2761 gcgccacgag gcgatctcga tcttgatgcc caggtcggcg agaaaccgcg acatgttggc
     2821 gatggtctgc tcgagcggca ggtccttgcc ggcgatatag gtgcgcgtgc cggtgtccgg
     2881 gtccagcgcc agcagggcct gggcgtcggc atcgaggtct gccacctcct cgacgacgaa
     2941 ctcggggccg gtctgcacca ccttcttgac cgtgcagcgc tcgatcgagc gcaggatgcc
     3001 ctggcggtcc ttggcggaga tgtcctccgg cagctcgacc tggatcttga agatctgctt
     3061 gtagcggttc tccgggtcga cgatgttgtt ctgcgacagg cggatgttct cggtcgggat
     3121 gttgcgggtc tcgcagtaca gcttcacgaa gtaggccgcg cacaaggccg acgaggccag
     3181 gaagtagtcg aacggccccg gcgccgagcc gtcgcccttg tagcggatcg gctggtcggc
     3241 gatcaccgtg aagtcgtcga acttggcttc gaggcgaagc ttgtcgagga agttgacctt
     3301 gatttccatg aggagggagg aatcctgaaa gggcgtgaac acgcgtcggg cggcattatc
     3361 gccggtttcg cgagggcgaa cgggttcgcg gctgccgccg ctccacatgc cctccggaag
     3421 cgcgccggtt catgtaggag cgccggcagg cgcgaatgcg gcgctgccct gcgccggcca
     3481 cgtcgatcga agagcggccg aattcgcggc tgccgccgct cctacatgag ctttccggaa
     3541 gcgcggcagt tgctgtagga gcgccggcag gcgcgaaagc ggccactccg acgtgcctac
     3601 gtgggcttcg tgcgcttcga ccgcggcagc tcggcgaagg cgatgcagtt caccaggttc
     3661 cacaccgcca gcatcgcgta cttgtcggac tcatcggccg cgatctcgcc cagccacttc
     3721 gacgtatcgc tcgccacgta ggcggcgagc gacttctcgg ggtgcgcgga gatgtagcgc
     3781 cgaagcgcgc gactgcgcag cgacggggtg atgtcctcgc cgaggcgcgt cgccgccacg
     3841 aagcgcgcga gctggcgctc ctgctcgtcc tccgtgatga ccggccaggc cagcccggac
     3901 tccttcatcg cctggaagca gaccagcagc accccgacgg caaactcgac cttctccatc
     3961 ggcaccccga gccggggcag caccaggatc gagcccagca tgttcggctg catgcggaag
     4021 atctcgtcgg cgaggcgttc tttctgcgcg cggtccatcg cctgaacggc atcgacggcc
     4081 ttctccaccg actcggtcga caaccggctc attcgacacc tccgcgcgat ccgcaggcac
     4141 gtcgttcacc cgccccaccg catgctcggc cgcggccacc cacacgcgct cggcgccagg
     4201 cggcaagggc gacggctgcc tgcgcgccga cgacgcggag gatcatccgc cggagctcag
     4261 cgtcgagagg ctgcgcgcag aacgtgtcgg tcagcgcggg gatggcggca aacttctccg
     4321 ccatggcctt ggaaacccgc tcggtggtcg tcatcggcaa acaggcaggg gacagggctc
     4381 ggcattgtcg cagagccgcc aggtcggcag ggctgcgggt ggaggactgg gttcgtgcga
     4441 tggacgccta attttcgtgg gtggcggcgt tgcggactcg tcgacatcct ttgctggcgc
     4501 aacggcaatc gtcgttcgag cggaggggct cttggtcggc ctgcttcgtc cttcgattct
     4561 gcggttgcat gcggagggga tggccgctcg ccggaatcct caattcaccc taacga
//
LOCUS       DAOTIN010000191         4603 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_22262_length_4603_cov_9.280563, whole genome shotgun sequence.
ACCESSION   DAOTIN010000191 DAOTIN010000000
VERSION     DAOTIN010000191.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 4603)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4603)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4603
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_22262_length_4603_cov_9.280563"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..599)
                     /locus_tag="P5537_16335"
     CDS             complement(<1..599)
                     /locus_tag="P5537_16335"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002931858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase"
                     /protein_id="HRV79656.1"
                     /translation="MKLLASLTSPYARKIRIILAEKALPFELVVDSPWEANTRIPEVN
                     PLGKVPVLITDEGETFFDSPVIAGYLETLGAPPALLPPAGLDAVRVRQTEALADGVTD
                     AALTALLESRRPDGERSEREIARQKDKIDRGLAELERRLDGRHAFNGSPMQLGDIAVA
                     VALGYLDLRFPELDWRRRHPGLVPFAERMFARDSLRDTQP"
     assembly_gap    901..1000
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(1132..1788)
                     /locus_tag="P5537_16340"
     CDS             complement(1132..1788)
                     /locus_tag="P5537_16340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004307680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HRV79657.1"
                     /translation="MSRPQPTEAVLLRGGAGNIEALIDAPATVKGIALVCHPHPLFGG
                     ANTNKVAHTLARAYRDLGYAVIRPNFRGVGKSEGAHDHGDGETEDMLAVISWAESRWG
                     ALPLALGGFSFGGYVQVRVANRLAEGIAPPRQLVLVGMAAGETTGSGRSYDTPALPKN
                     IPALVIHGEDDDTVALANVLAWARPQEQPIIVIPGADHFFHGKLHLIRELIARNVAHA
                     "
     gene            complement(1785..2108)
                     /locus_tag="P5537_16345"
     CDS             complement(1785..2108)
                     /locus_tag="P5537_16345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HRV79658.1"
                     /translation="MSYFKHHVFFCCNQRQPGESCCNDHKASELQTYAKERTAALGLK
                     GKGSVRVNKAGCLGRCDDGPVIVVYPDNVWYTYVDKEDIDEIIDSHLVHGRVVQRLRL
                     PEDAA"
     gene            complement(2138..3238)
                     /locus_tag="P5537_16350"
     CDS             complement(2138..3238)
                     /locus_tag="P5537_16350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004361122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HRV79659.1"
                     /translation="MASRPHVHLAQSLALGYTLLVAYACLHPLAGWRDSGLPALDWLW
                     APWPKYFILEDFVFNILGYLPLGLLAAAALPAAWGPRRKVAVATLFAGLLSLGLEAAQ
                     NFLPSRVASNLDLGGNIAGALIGALAGAHWGEGLLGPQGRLQRWRARYVIGGRSGEAG
                     LMLLVLWLLGQLGATDLLFATGDLRSLLGIPPPLPFRPERFIAFDTALTASALLAIAL
                     FTRCMTRGANPLPVLVVLALGIGAKTLATWTFFHPGAPLAWLTPGAERGLVVGSLLLL
                     PCLLLPRLAQHALAGSCLLVATALVNLIPENPYLAYGRRLADISNVLNFHGLTQLVDS
                     LWPFVALAYLSALGLWRGEHLGGAPPRSARRL"
     gene            complement(3351..4433)
                     /locus_tag="P5537_16355"
     CDS             complement(3351..4433)
                     /locus_tag="P5537_16355"
                     /inference="COORDINATES: protein motif:HMM:NF012385.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HRV79660.1"
                     /translation="MTTRSSLEAPRSATTGRVPPPQPVANAEASFAEFGLLGEAACFR
                     SALELVRRFAETTAHVLIQGETGTGKELVARAIHYLGPRRYKPFVAINCGALPDNLVE
                     NELFGHARGAFTDARDSQPGVIAEADGGTLFLDEIECLSHKGQVALLRFLQDGHYRPL
                     GGRGMVQADVRVVAASNREFDEMVREGSFRQDLLYRLAIMSVSLPPLRARGDDVLLLV
                     DHFLRRFARSYGRPRPVVDAESRRQALAYSWPGNIRELENAVHRQFLLADGGNLRLEL
                     APQPDAPMPASTAAGVEGLADMDMKTAKAAVIERFERDYLEQLITATGGNVSAAAQRA
                     GKERRAFGKLLKKYGIERERFGRRRA"
BASE COUNT          633 a         1522 c         1714 g          634 t
ORIGIN      
        1 ggctgggtgt cgcgcaggct gtcgcgggcg aacatgcgct cggcgaaggg caccaggccg
       61 gggtggcggc ggcgccagtc gagctcgggg aagcgcaggt cgaggtagcc gagcgcgacc
      121 gcgaccgcga tgtcgccgag ctgcatcggg ctgccgttga aggcgtggcg gccgtccagg
      181 cggcgttcga gctcggcgag gccgcggtcg atcttgtcct tctggcgggc gatctcacgc
      241 tcgctgcgct cgccgtctgg gcggcgcgac tcgagcaggg cggtgagcgc cgcgtcggtg
      301 acgccgtcgg cgagcgcctc ggtctggcgt acgcgcaccg cgtcgagccc ggcgggcggc
      361 agcagcgcgg gcggagcgcc gagggtctcg agatagccgg cgatgaccgg cgaatcgaag
      421 aaggtctcgc cttcgtcggt gatcagcacc ggcaccttgc cgagcgggtt cacctccggg
      481 atgcgggtgt tggcctccca cggcgagtcg accacgagct cgaagggcag cgccttctcc
      541 gcgaggatga tgcggatctt gcgcgcgtag gggctggtga gcgaggcgag cagtttcatg
      601 atggcgggtc tccgttggtg gccgacccag ggtacgccgc aggcgggtgg gggaaaatca
      661 gggaaaccgg aagggggagg ggcgacccgg ggcgagcgga tgttcgcgcc tgccggcgct
      721 cctgcagcaa ccaccgctcg tccaggactc gcctgtagga gctgcggcag ctgcgaaccc
      781 ggcgctccag cgcccgacgc gcctgcagag ctgcgccgta gccttcgcgc ctgccggcgc
      841 tcctacagca accaccgctc gtccaggact cgcctgtagg agctgcggca gctgcgaacc
      901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn cccgacgcgc ctgcagagct
     1021 gcgccgtagc cttcgcgcct gccggcgctc ctacatcgag cggcgcggct ggatgccgtg
     1081 caggagcggc ggcagccgcg aatgcaacgc tgccgtgcgt gccgcgcgat ctcaggcgtg
     1141 cgccacgttg cgtgcgatga gctcgcggat caggtgcagc ttgccgtgga agaagtggtc
     1201 ggcgccgggg atgacgatga tcggctgctc ctgcggccgt gcccaggcga gcacgttggc
     1261 gagcgccacg gtgtcgtcgt cctcgccgtg gatgaccagc gcggggatgt tcttcggcaa
     1321 ggccggcgtg tcgtagctgc gcccgctgcc cgtggtctcg ccggcggcca tgcccaccag
     1381 cacgagctgg cgcggcggcg cgatgccctc ggccaggcgg ttggcgacgc gcacctgcac
     1441 gtagccgccg aaggagaagc cgccgagcgc cagcggcagc gcgccccagc gcgactccgc
     1501 ccagctgatc accgccagca tgtcctcggt ctcgccgtcg ccgtggtcgt gcgcgccctc
     1561 gctcttgccc acgccgcgga agttggggcg gatcaccgcg tagccgaggt cgcggtacgc
     1621 gcgtgccagc gtgtgcgcga ccttgttggt gttggcgccg ccgaagagtg ggtgcgggtg
     1681 gcagaccagc gcgatgccct tgaccgtggc gggggcatcg atcagcgcct cgatgttgcc
     1741 ggcgccgccg cgcagcagga cggcctcggt gggctgcggg cggctcacgc ggcgtcctcc
     1801 ggcaggcgca ggcgctggac cacgcggccg tgcacgaggt gcgagtcgat gatctcgtcg
     1861 atgtcttcct tgtcgacgta ggtgtaccag acgttgtcgg ggtagacgac gatcaccggg
     1921 ccgtcgtcgc agcgcccgag gcagcccgcc ttgttgacgc gcacgctgcc cttgcccttg
     1981 aggccgagcg cggcggtgcg ttccttggcg taggtctgca gctcgctcgc cttgtggtcg
     2041 ttgcagcagg actcgcccgg ctggcgctgg ttgcagcaga agaagacgtg gtgtttgaag
     2101 tagctcatgg ggcgctctct ggttcggggc ctgccgatta taggcggcgc gcgctgcgcg
     2161 ggggcgctcc gccgaggtgc tcgccacgcc acagcccgag cgcggagaga taggccagcg
     2221 cgacgaaggg ccacaggctg tcgacgagct gggtcaggcc gtggaagttg agcacgttgc
     2281 tgatgtcggc gagccggcgc ccataggcca ggtaggggtt ctcggggatc aggttgacca
     2341 gcgcggtggc cacgagcagg caggagcccg ccagcgcgtg ctgcgccagc cgcggcagca
     2401 gcaggcaggg cagcagcagc aggctgccca ccacgaggcc gcgctcggcg cccggcgtga
     2461 gccaggccag cggcgcaccg ggatggaaga aggtccacgt ggccagggtc ttggcgccga
     2521 tcccgagcgc gagcaccacc agcaccggca gcgggttggc gccgcgcgtc atgcagcggg
     2581 tgaacagcgc gatcgcgagc agggcgctgg ccgtgagcgc ggtgtcgaag gcgatgaagc
     2641 gctcgggacg gaagggcagc ggcggcggaa tgccgagcag gctgcgcagg tcgccggtgg
     2701 cgaacagcag gtcggtggcg ccgagctgcc cgagcagcca cagcaccagc agcatcaggc
     2761 cggcctcgcc gctgcgcccg ccgatgacgt agcgagcgcg ccagcgctgc aggcggcctt
     2821 gcgggccgag caggccctcg ccccagtgcg cacccgcgag cgcgccgatg agggccccgg
     2881 cgatgttgcc gccgaggtcg aggttgctgg cgacgcggct gggcaggaag ttctgcgccg
     2941 cctccaggcc caggctgagc aggccggcga acagcgtggc gacggccacc ttgcgccgcg
     3001 gcccccaggc tgcaggcagc gccgcggcag cgagcagccc gagcggcagg taacccagga
     3061 tgttgaagac gaagtcttcg aggatgaaat atttcggcca cggcgcccat agccagtcga
     3121 gcgccggcag cccgctgtcg cgccagccgg cgagcgggtg caggcaggca taggcgacga
     3181 gcagggtgta accgagtgcc aggctttgag ccaggtggac gtggggacgg gaggccatgg
     3241 gcgcgttgcc ggacgtcgcg ggcgacgccg gcgacaggag ttcgcaaacc cgcgcagtgt
     3301 agccgctcga cgctgccgcc gtgacgcccg cgggcacgcg gcgtacgcgc tcaggcgcgc
     3361 cgccgcccga agcgttcgcg ctcgatgccg tacttcttca gcagcttgcc aaaggcgcgg
     3421 cgctccttgc cggcgcgctg cgcggcggcc gaaacgttgc cacccgtggc ggtgatgagc
     3481 tgctcgaggt agtcgcgctc gaagcgttcg atcaccgctg ccttcgccgt cttcatgtcc
     3541 atgtcggcga ggccttcgac cccggctgcg gtgctcgccg gcatcggcgc gtcgggctgc
     3601 ggcgccagct ccagcctcag gttgccgccg tcggcgagca ggaactggcg gtgcaccgcg
     3661 ttctcgagct cgcggatgtt gcccggccag gaatacgcga gcgcctgccg ccgcgactcg
     3721 gcatccacca ccggccgtgg ccgcccgtag ctgcgcgcga agcggcgcag gaaatgatcg
     3781 acgagcagca gcacgtcgtc gccgcgcgcg cgcaacggtg gcagcgacac cgacatgatc
     3841 gccaggcggt agagcaggtc ctggcgaaag ctgccctcgc gcaccatctc gtcgaactcg
     3901 cggttgctcg ccgccaccac ccgcacgtct gcctgcacca tgccgcgccc gcccagcggt
     3961 cggtagtggc cgtcctgcag gaagcgcagc agcgccacct gtcccttgtg cgacaggcat
     4021 tcgatctcgt cgaggaacag cgtgccgccg tcggcctccg cgatcacgcc gggctggctg
     4081 tcgcgcgcgt cggtgaaggc gccgcgcgcg tggccgaaga gctcgttctc gaccaggttg
     4141 tcgggcagcg ccccgcagtt gatcgccacg aaaggcttgt agcggcgcgg gccgagatag
     4201 tggatggcgc gcgcgacgag ctccttgccg gtgccggtct cgccctggat gaggacatgc
     4261 gcggtggtct cggcaaagcg ccgcacgagc tccagtgcgg agcggaagca ggcggcttca
     4321 ccgagcagcc cgaactcggc gaagctcgcc tccgcgttcg cgaccggctg cggtggcggt
     4381 acgcgaccgg tcgtcgcgct ccgcggggct tcgaggctcg agcgggtggt catccatcgt
     4441 ctcccgtggc tggcatgcgc aggcgggctc catcctcgcc gcgcccgggg gcggcgcatg
     4501 gcccgtcggc gggtgcgtcc ggggcctggc tggagccaag gctctcccat caatctgggc
     4561 tacccaggct gagccgtcaa acagcgttac atgttcgacg cgt
//
LOCUS       DAOTIN010000192         4572 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_22451_length_4572_cov_6.702457, whole genome shotgun sequence.
ACCESSION   DAOTIN010000192 DAOTIN010000000
VERSION     DAOTIN010000192.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 4572)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4572)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4572
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_22451_length_4572_cov_6.702457"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(75..776)
                     /gene="mtgA"
                     /locus_tag="P5537_16360"
     CDS             complement(75..776)
                     /gene="mtgA"
                     /locus_tag="P5537_16360"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004335738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009274 - peptidoglycan-based cell wall
                     [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="monofunctional biosynthetic peptidoglycan
                     transglycosylase"
                     /protein_id="HRV79661.1"
                     /translation="MPAPRRMLGWLARGLGIALLLALFWQAVLLTQVVWWSRFDPGST
                     SFMRIRLAELRKSDPQAELRHRWVPYERISIHLKRAVVAAEDDRFLDHDGFDWEGIER
                     ALERNAEEGRITAGGSTISQQLAKNLFLSSSRSWLRKGQEAAITMMIEATWDKRRILE
                     VYLNVAEWGNGVFGAEAAARHYHGRPAASLGPAEAARLAVMLPNPRRYEKSFGPRLAA
                     HAARVQRRMVNSQVP"
     gene            complement(790..1623)
                     /gene="aroE"
                     /locus_tag="P5537_16365"
     CDS             complement(790..1623)
                     /gene="aroE"
                     /locus_tag="P5537_16365"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004371937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HRV79662.1"
                     /translation="MDRYAVVGNPIAHSKSPWIHAAFARQTGQALAYEALLAPLDDFA
                     GTVARFRAEGGRGLNVTVPFKLEAFALAGQRTPRAEAAGAVNTLAFGADGLLGDNTDG
                     AGLVRDLAINLGCSLAGRRILLLGAGGATRGVLLPLLDSAPARLCIANRTPHKAVELA
                     QGFAPHAGTTRIDGCGFDVVAGERFDLVINATAASLSGELPPLPPGLYADGALAYDMM
                     YGRGHTPFLRAALADGAARVADGLGMLVEQAAESFALWRGVRPDSAPVLTELRRLVEA
                     G"
     gene            complement(1634..2557)
                     /locus_tag="P5537_16370"
     CDS             complement(1634..2557)
                     /locus_tag="P5537_16370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy transducer TonB"
                     /protein_id="HRV79663.1"
                     /translation="MSATAAPNLPAGALPGAWSGRLRRFGGPLLAAAFIVSISLHALL
                     LLIHFRLPEAKPARDKGLEVVLVNARHAQAPEKAEVLAQANIDAGGNTEQEVRASTPL
                     PPQPNRQDGDALVEAKRRTPEPVREQKQVITRDKAPARVAAAPKKVEQPAPTPEPQRE
                     ISGLDLLDSAAAVARIEAQIDRDLKELAKRPRKKFIGARAQEYRFAQYVEDWRQKVER
                     IGTLNYPEAARGRLYGSLLLSVTIRSDGTVERVGVHRSSGHKVLDDAALRIVKMAAPY
                     APFPPDIRKDYDVIEITRTWTFTNSDQVRAN"
     gene            complement(2565..>4572)
                     /locus_tag="P5537_16375"
     CDS             complement(2565..>4572)
                     /locus_tag="P5537_16375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - ribonuclease activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="RNB domain-containing ribonuclease"
                     /protein_id="HRV79664.1"
                     /translation="LKAPQMMIEDVTITHESCSGSKDGSIELEISGGTPNYVVNWGVG
                     VGVGNPIGNLSGGMYTATITDNNGCKITSPTLTVNSSSLNPAIAKTDVTCFGSGNGTI
                     TITLPPTGGPYTVTWDPTSAGSGPNLINLGPGAYTPTIVDGSGCITELEPIFIFQPDD
                     ITLDGKTTPVLCAGQAQGSINLTATGGNGTFTYKWSNNAVTEDLINVVSGNYSVTVTD
                     GNNCTKTGSYTITGPSNPLTVTAVTTPTTINQSTGTITLTVTGGNPNYTYLWSNNAVT
                     KDLTALSAGSYTVTVTDSNGCTKTLTTTVSNADDNVVTFDRVDYNGFNISCYGQCDGT
                     AVAFAPGSAAQPVTFTLAEGRDCPAVSLYLDITPGLAIVGEESRVELVPIVANLRHHD
                     IEPVFNDDTVHNGGPDFQWKRELTLLWDLATVLEAGRGKAAGNEDRIDFGFSVDWTEE
                     TADGPGRVSIGRRLRGSPMDKLVAELMIYANMTWGKLLDTSGIPGLYRAQGGGKVRMT
                     TVAAPHEGLGVDCYAWSSSPLRRYVDLVNQWQIVSVLQGTDPAFAPKSAELMAAMRDF
                     ELTYAEYAEFQRGMERYWCLRWLRQHGRGEVEATVLRESVVRLTEIPLVFRVPSMPLQ
                     MPGSRVKLFVERTDLLDVEVEARFVQTLAEPDPATVDETGFGFA"
BASE COUNT          665 a         1495 c         1645 g          767 t
ORIGIN      
        1 gaccccgatc atgtgacaga gggcgaaaaa gcccccattc ccgcccctcg cacctaacac
       61 ctcacgcctc acgctcacgg cacctgcgaa ttgaccatcc gccgctgcac ccgcgccgcg
      121 tgcgcggcca ggcgggggcc gaaggacttc tcgtagcgcc gcgggttggg cagcatcacc
      181 gccaggcgcg cggcctcggc cgggcccagg ctggcggcgg ggcggccgtg gtaatggcgg
      241 gcggcggctt cggcgccgaa tacgccattg ccccattcgg ccacgttcag gtacacctcg
      301 aggatgcggc gcttgtccca ggtcgcctcg atcatcatcg tgatcgccgc ctcctggccc
      361 ttgcgcagcc acgagcgcga cgaggacagg aacagattct tggcgagctg ctggctgatc
      421 gtcgagccgc cggcggtgat gcggccctcc tcggcgttgc gctcgagggc gcgctcgatg
      481 ccctcccagt cgaagccgtc atgatcgagg aagcggtcgt cttcggcggc gaccaccgcg
      541 cgcttgagat ggatcgagat gcgctcgtag ggcacccatc ggtggcgcag ctcggcctgc
      601 gggtcgctct tgcgcagctc ggcgaggcgg atgcgcatga agctggtgct gccggggtcg
      661 aagcggctcc accacaccac ctgggtcagc agcaccgcct gccagaacag cgccagcagc
      721 agcgcgatgc ccagcccgcg tgcgagccag ccgagcatgc ggcgcggcgc gggcatcggc
      781 acggcggcct cagccggctt cgacgagccg gcgcagctcg gtcagcaccg gcgcggagtc
      841 ggggcgcacc ccgcgccaca gcgcgaagct ctcggcggcc tgctcgacca gcatgccgag
      901 cccgtcggcc acccgcgccg cgccgtcggc aagcgccgcg cgcaggaagg gggtgtggcc
      961 gcgtccgtac atcatgtcgt aggccagcgc gccgtctgcg tacagcccgg gcggcagcgg
     1021 cggcagctcg ccggagaggc ttgctgccgt ggcgttgatc acgaggtcga agcgctcgcc
     1081 ggcgaccacg tcgaaaccgc agccgtcgat gcgcgtggtg ccggcgtggg gggcgaagcc
     1141 ctgcgccagc tccaccgcct tgtgcggcgt gcggtttgcg atgcacaggc gcgcgggggc
     1201 gctgtcgagc agcggcagca acacgccgcg ggtcgcgccg ccggcgccca gcagcaggat
     1261 gcgacgaccg gcgagcgagc atcccaggtt gatcgcgagg tcgcgcacca ggccggcgcc
     1321 gtcggtgttg tcgccgagga ggccgtctgc cccgaaggcg agcgtgttga ccgcgccggc
     1381 cgcctcggcg cgcggcgtgc gctggccggc gagggcgaag gcctcgagct tgaagggcac
     1441 ggtgacgttg aggccgcgtc cgccctcggc gcggaagcgc gccaccgtgc cggcgaagtc
     1501 gtcgaggggg gcgagcaggg cctcgtaggc gagcgcctgc ccggtctggc gcgcgaaggc
     1561 ggcgtggatc cagggcgact tgctgtgggc gatcgggttg ccgacgacgg cgtagcggtc
     1621 catgggcggg gtctcagttg gcgcgcacct ggtcgctgtt ggtgaaggtc caggtgcggg
     1681 tgatctcgat cacgtcgtag tccttgcgga tgtcgggcgg gaagggcgcg tagggcgcgg
     1741 ccatcttgac gatgcgcagc gcggcgtcgt cgagcacctt gtggcccgag ctgcgatgca
     1801 cgcccacccg ttccacggtg ccgtcggagc ggatcgtcac cgacagcagc aggctgccat
     1861 acagccggcc gcgcgcggcc tcggggtagt tcagggtgcc gatgcgctcg accttctgcc
     1921 gccagtcctc gacatactgc gcgaagcggt attcctgcgc gcgcgcgccg atgaacttct
     1981 tgcgcgggcg cttggccagc tccttgaggt cgcggtcgat ctgggcttcg atgcgggcca
     2041 ccgcggcggc gctgtcgagc aggtcgaggc cgctgatctc gcgctgcggc tcgggcgtcg
     2101 gtgcgggctg ctcgaccttc ttcggcgccg ccgcgaccct ggccggcgcc ttgtcgcggg
     2161 tgatcacctg cttctgctcg cgcaccggct cgggcgtgcg gcgcttggcc tcgaccaggg
     2221 cgtcgccgtc ctggcggttg ggctgtggcg gcagcggcgt gcttgcgcgc acctcctgct
     2281 cggtgttgcc accggcatcg atgttggcct gggcgagcac ctcggccttc tcgggcgcct
     2341 gcgcgtggcg ggcgttgacc agcaccacct ccaggccctt gtcgcgcgcc ggcttggcct
     2401 cgggcaggcg gaagtggatc aacagcaaca gcgcgtgcag gctgatcgag acgatgaagg
     2461 ccgccgccag cagcggtccg ccgaagcgcc gcaggcgtcc gctccacgcc cccggcaggg
     2521 cgccggcggg caggttgggg gcggcggtcg cgctcatgcg tggatcaggc gaaaccgaag
     2581 ccggtctcgt ccaccgtcgc ggggtcgggt tcggcgagcg tctgcacgaa gcgcgcctcg
     2641 acctcgacgt cgagcaggtc ggtgcgctcg acgaagagct tgacccggct gcccggcatc
     2701 tgcagcggca tcgagggtac gcggaagacc agcgggatct cggtgaggcg caccacgctc
     2761 tcgcgcagca ccgtggcctc gacctcgccc cggccgtgct ggcgcagcca gcgcaggcac
     2821 caatagcgct ccatgccgcg ctggaattcg gcgtactcgg cgtaggtgag ctcgaagtcg
     2881 cgcatcgccg ccatcagctc ggccgacttg ggcgcgaagg cggggtcggt gccctgcagc
     2941 accgaaacga tctgccactg gttgaccaga tccacgtagc gccgcagcgg cgagctcgac
     3001 caggcgtagc agtccacccc gaggccttcg tgcggcgcgg cgaccgtggt catgcgcacc
     3061 ttgccgccgc cctgggcgcg gtacaggccg gggatgccgg aggtgtcgag gagcttgccc
     3121 caggtcatgt tggcgtaaat catcagctcg gcgacgagct tgtccatcgg cgagccgcgc
     3181 aggcgccggc cgatgctgac gcgccccggg ccgtcggcgg tctcctcggt ccagtccacg
     3241 ctgaagccga aatcgatgcg atcctcgttg cctgcggcct tgccgcgtcc ggcctcgagg
     3301 acggtggcga gatcccacag cagggtcagc tcgcgcttcc actggaagtc ggggccgccg
     3361 ttgtgcacgg tgtcgtcgtt gaagacgggc tcgatgtcgt ggtggcgcag gttggccacg
     3421 atcggcacga gctctacccg gctctcttcg ccgacgatcg ccagccccgg ggtgatgtcg
     3481 aggtagagcg acaccgccgg gcagtcgcgg ccctcggcca gggtgaaggt cacaggttgg
     3541 gctgctgatc cgggagcaaa ggcgacggcg gtaccgtcac actggccata gcaggaaatg
     3601 ttgaaaccat tgtagtcgac ccgatcgaag gtgaccacat tgtcatctgc attggatacc
     3661 gtagtggtca gggtctttgt acaaccattg ctgtccgtga ccgtcacggt atatgagcca
     3721 gcagagaggg ccgtcaggtc cttcgtgacg gcattgttgc tccacaggta ggtgtagttg
     3781 gggttgccgc cggtgacggt cagggtgatc gttccggtcg actgattgat cgtcgtcggc
     3841 gtggtcacgg cggttaccgt caatgggttc gatggaccgg tgatggtgta gctgcccgtc
     3901 ttggtgcagt tgtttccatc ggtcaccgtg acgctataat tgccactgac cacattgatc
     3961 agatcctcgg taacggcgtt gttgctccac ttgtaggtga aggtgccgtt gccaccggtg
     4021 gcagtgagat tgatggatcc ctgggcctgt ccggcacaca gcactggtgt ggtcttgcca
     4081 tccagagtga tgtcatccgg ctggaagatg aagatcggct ccagctcggt gatacaaccg
     4141 ctgccatcca caatggtggg ggtgtaggcc cccgggccaa gattgatgag gttgggccct
     4201 gatccggctg aggtcggatc ccaggtcacc gtgtagggtc ctccggttgg cggcaatgta
     4261 atggtaatgg tgccgttgcc ggaaccaaaa caggtcacat ccgtcttggc aatggccgga
     4321 ttcagactgg agctgttcac ggtcagggtc ggactggtga tcttgcagcc gttattgtcc
     4381 gtgatggtgg cggtatacat gccgcccgac aggttgccga tcgggttgcc gacaccgacg
     4441 ccgacgcccc agttcaccac atagttgggt gttccgccgg agatctccag ctcgatgctg
     4501 ccatccttgc tccccgagca ggattcatgg gtaatggtca catcctcgat catcatctga
     4561 ggggccttca gc
//
LOCUS       DAOTIN010000193         4493 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_22940_length_4493_cov_9.302839, whole genome shotgun sequence.
ACCESSION   DAOTIN010000193 DAOTIN010000000
VERSION     DAOTIN010000193.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 4493)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4493)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4493
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_22940_length_4493_cov_9.302839"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(161..667)
                     /locus_tag="P5537_16380"
     CDS             complement(161..667)
                     /locus_tag="P5537_16380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00645 family protein"
                     /protein_id="HRV79665.1"
                     /translation="MKRVESSFEHVLFTSRWLMAPVYFGLVLAMVLLLVKFGKELFGL
                     FAQIWTASGSELIIGVLSLVDVALIMNLLIIIIFSGYENFVSKMEDLHTHRDRPEWMG
                     HIGFSDLKLKLIGSIVAISGIELLKAFMNAHNLTDRQLGWMVGIHVTFLFSGLLYAAM
                     DRLAGKGH"
     gene            complement(693..1430)
                     /locus_tag="P5537_16385"
     CDS             complement(693..1430)
                     /locus_tag="P5537_16385"
                     /EC_number="2.4.2.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-methyl-5'-thioinosine phosphorylase"
                     /protein_id="HRV79666.1"
                     /translation="MLAIIGGSGLTQLSNMEIERREVVRTPYGEPSGALAFGRVCDEP
                     VVFLARHGYGHTIPPHLVNYRANIWALKQAKATGIVSVASVGGIRADLAPGTLIVPNQ
                     IIDYTWGRKSTFFEGGDTPVRHIDFTEPYDEALRRRLLAAIRAAGDSAVDGGVYASTQ
                     GPRLESAAEIDRLERDGCDIVGMTGMPEAALARELELPYAAIGVVVNYAAGRSSSAHG
                     IHFDDIELVLQESMVRVRAVLEGLCHV"
     gene            1552..3369
                     /gene="typA"
                     /locus_tag="P5537_16390"
     CDS             1552..3369
                     /gene="typA"
                     /locus_tag="P5537_16390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HRV79667.1"
                     /translation="MSRAIRNIAIIAHVDHGKTTLVDQLLRQSGTFRENQQVAERVMD
                     SGDIEKERGITILSKNCAIQYGDTHINIVDTPGHADFGGEVERVLSMVDSVLLLVDAV
                     EGPMPQTRFVTRKALALGLKPIVVINKIDRPGARPDWVINHTFDLFDKLGATEEQLDF
                     PVIYASGLNGFAVINEGDERKDMRPLFEAILEHVPAPEVDANGPLQIQVCSLDYSTYM
                     GQLGIGRIKRGRVRPNQEVVVMYGEENRGKGKVSQILTFEGLERKPSEMAEAGDIVLI
                     AGIQQVNIGVTLCDPECLEGMKPIAVDEPTLTMNFMVNTSPLAGREGKYVTSRQIRER
                     LEKELLKNVALRVNYTGDSDVFEVSGRGELHLTILLENMRREGYELAVGRPRVVYKEI
                     DGVKCEPYEMLTVDVEEDHQGSVMEELGRRRGELQDMQPDGKGRVRLEYRIPARGLIG
                     FQGEFLTMTRGTGLASHVFDDYGPMAGPMAERRNGVLISQNDGEAVAYALWNLQDRGR
                     MFVSPGEALYEGMIIGIHTRDNDLVVNPIKGKQLTNVRASGTDEAVRLITPIALTLES
                     AIEFIADDELVEITPKNIRLRKRHLKETDRKRAAKAAEA"
     gene            complement(3526..3999)
                     /locus_tag="P5537_16395"
     CDS             complement(3526..3999)
                     /locus_tag="P5537_16395"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002930073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HRV79668.1"
                     /translation="MKRILFVCTGNICRSPTAEAVARHFVETGGLGAQVLLDSAGTQG
                     YHVGEAPDPRTQKAAKLRGYDLSALRARKLELRDFQEFDLLLAMDRGHLEHMQRHCPE
                     VYRPKLQLFLPFTGAERYGEEVPDPYYGGPKGFDLVLDMCEDGARGIVERVRQEA"
     gene            complement(4024..>4493)
                     /locus_tag="P5537_16400"
     CDS             complement(4024..>4493)
                     /locus_tag="P5537_16400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HRV79669.1"
                     /translation="ILDADKEGFLRSERSLIQTIGRAARHLHGTAILYADRVTDSMKA
                     AIGETERRRQKQIAFNEANGIVPKSVTKRIKDIIDGVYDADGAKRDVARVAEKGGDYA
                     AMDEKSLARAIKRLEKEMQEHARNLEFEKAAAARDELFKLRERAFGADQHGSV"
BASE COUNT          788 a         1567 c         1452 g          686 t
ORIGIN      
        1 cctacatgaa cccacggggc ggggacatga acccacgggg cggggacatg aacccgcggg
       61 gcggggacat gcaagcgcgc gacctgaaat atgagccccc gcggacgcat cccgtgcagg
      121 agcaccggca ggcgcgaaag cggcggcggg gcgccggcgc tcagtggccc ttgcccgcca
      181 ggcggtccat ggccgcgtag agcaggcccg agaacaggaa ggtgacgtgt atgcccacca
      241 tccagccgag ctggcggtcg gtgaggttat gggcgttcat gaaggccttc agcagctcga
      301 tcccggagat cgccacgatc gagccgatca gcttgagctt gaggtcggaa aagccgatgt
      361 gccccatcca ctccgggcgg tcgcggtggg tgtgcaggtc ttccatcttg gagacgaagt
      421 tctcgtagcc gctgaagatg atgatgatca gcaggttcat gatcagcgcc acgtcgacca
      481 gggagagcac gccgatgatc agctcgctgc ccgaggcggt ccagatctgc gcgaacagcc
      541 cgaacagctc cttgccgaac ttcaccagca gcaacaccat cgccagcacc aggccgaaat
      601 acaccggcgc catcagccag cggctggtga atagcacgtg ctcgaacgag ctctcgaccc
      661 gcttcatcgc attgacctcc tcgctcggtc gatcagacat ggcaaagccc ctcgagcacg
      721 gcgcgcacgc gcaccatgga ctcctgcagc acgagttcga tgtcgtcgaa atggatgccg
      781 tgcgcgctcg acgagcgccc cgcagcgtaa ttgaccacca cgccgatcgc ggcgtagggc
      841 agctcgagct cgcgcgccag cgccgcctcg ggcatgccgg tcatgccgac gatgtcgcat
      901 ccatcgcgct cgaggcggtc gatctcggcg gcgctctcca ggcgcggtcc ctgggtgctc
      961 gcgtagacgc ctccatccac cgcgctgtcg ccggcggcgc ggatcgccgc gagcaggcga
     1021 cggcgcaggg cctcgtcgta tggctcggtg aagtcgatat ggcgcaccgg cgtgtcgcca
     1081 ccctcgaaga aggtgctctt gcgcccccag gtgtagtcga tgatctggtt cggcacgatc
     1141 agcgtgccgg gcgcgaggtc ggcacggatg ccgcccaccg aggcgacgga gacgatgccg
     1201 gtggccttgg cctgcttgag cgcccagatg ttggcgcggt aattgaccag gtgcggcggg
     1261 atggtgtggc cgtagccgtg gcgggcgagg aagacgaccg gctcgtcgca gacgcgaccg
     1321 aaggcgagcg cgcccgaggg ctcgccgtag ggcgtgcgca caacctcgcg gcgctcgatc
     1381 tccatgttcg acaattgggt gagtccgctg ccgccgatga tcgcgagcat ggtgaagaga
     1441 cctttcttgg ctggggcgcg cgattctagc acgcccccca gaaatccatg ctgcgctgcc
     1501 acagcacgtg ctagaatcct cgccctttca aagacttcgc cgccctcctc catgtcacgc
     1561 gccattcgca acatcgccat catcgcccac gtcgaccacg gcaagaccac cctcgtcgac
     1621 caactgctgc gccagtccgg caccttccgc gaaaaccagc aggtcgcaga acgcgtcatg
     1681 gactcgggtg acatcgagaa ggaacgcggc atcacgatcc tctcgaagaa ctgcgccatc
     1741 cagtacggcg acacccacat caacatcgtc gacaccccgg gccacgccga cttcggcggc
     1801 gaggtcgagc gcgtgctgtc gatggtcgac agcgtgctgc tgctggtcga cgcggtcgaa
     1861 ggcccgatgc cgcagacccg cttcgtcacc cgcaaggcgc tcgcgctggg cctcaagccg
     1921 atcgtcgtca tcaacaagat cgaccgcccg ggcgcgcgtc cggactgggt gatcaatcat
     1981 accttcgacc tcttcgacaa gctcggcgcc accgaggagc aactcgactt cccggtgatc
     2041 tacgcctcgg gcctgaacgg cttcgcggtg atcaacgagg gcgacgagcg caaggacatg
     2101 cgcccgctgt tcgaggccat cctcgagcac gtgcccgcac cggaagtcga cgccaacggc
     2161 ccgctgcaga tccaggtgtg ctcgctcgac tactcgacct acatgggcca gctcggcatc
     2221 ggccgcatca agcgcggccg cgtgcgcccc aaccaggaag tcgtcgtcat gtacggcgag
     2281 gagaaccgcg gcaagggcaa ggtcagccag atcctcacct tcgagggcct ggagcgcaaa
     2341 ccctccgaga tggccgaggc cggcgacatc gtgttgatcg cgggcatcca gcaggtcaac
     2401 atcggtgtca ctctgtgcga cccggagtgc ctcgagggca tgaagccgat cgcggtggac
     2461 gagccgacgc tgaccatgaa cttcatggtc aacacctcgc cgctcgccgg tcgcgaaggc
     2521 aagtacgtca ccagccgcca gatccgcgaa cgcctggaaa aggagctgct caagaacgtc
     2581 gccctgcgcg tgaactacac cggcgactcg gacgtgttcg aggtctccgg ccgcggcgag
     2641 ctccacctca ccatcctgct cgagaacatg cgccgcgaag gctatgagct ggcggtgggc
     2701 cgcccgcgcg tggtttacaa ggagatcgac ggcgtcaagt gcgagcccta cgagatgctc
     2761 accgtcgacg tcgaggaaga ccaccagggc agcgtcatgg aagagctcgg ccgccgccgt
     2821 ggcgaactcc aggacatgca gccggacggc aaggggcgcg tgcgcctcga gtaccgcatc
     2881 ccggcgcgcg gcctgatcgg cttccagggc gaattcctca ccatgacgcg cggcaccggc
     2941 ctcgccagcc acgtcttcga cgactacggc ccgatggccg gcccgatggc cgagcgccgc
     3001 aacggcgtgc tgatctcgca gaacgacggc gaggcggtgg cctacgcgct gtggaacctg
     3061 caggaccgcg gccgcatgtt cgtgagcccg ggcgaggcgc tgtacgaggg catgatcatc
     3121 ggcatccaca cccgcgacaa cgacctcgtg gtgaacccga tcaagggcaa gcagctcacc
     3181 aacgtgcgcg cctcgggcac cgacgaggcc gtgcgcctga tcacgccgat cgcgctgacg
     3241 ctggaatccg cgatcgagtt catcgccgac gacgaactgg tcgagatcac gcccaagaac
     3301 atccgcctgc gcaagcgtca cctcaaggaa accgaccgca agcgcgctgc caaggccgcc
     3361 gaggcctgag cgccggcgac gggagatcgg gcgggacggt cgccgctgcc gccgcttcgc
     3421 ccccgccagt cgcgcggggc ggcggcggcg acattggcgc gatgctgcga gcgcgcaggc
     3481 cggactcgct catctcccgc ccggatgagc ccgcgcccct ccgactcacg cctcctgccg
     3541 cacccgctcc acgatcccgc gcgccccgtc ctcgcacatg tcgagcacca ggtcgaagcc
     3601 cttcggcccg ccgtagtaag gatcgggcac ctcctcgccg taccgctccg cccccgtgaa
     3661 gggcaggaag agctgaagct tgggccgata tacctcgggg caatggcgct gcatgtgttc
     3721 cagatgcccg cggtccatcg ccagcagcag gtcgaactcc tggaaatccc gcagctccag
     3781 cttgcgcgcg cggagcgcgg acaggtcgta gccacgcagc ttggccgcct tctgcgtgcg
     3841 tggatcgggc gcctcgccga cgtggtagcc ctgcgtgccg gccgagtcga gcagcacctg
     3901 cgcgcccagc ccgccggtct cgacgaaatg gcgcgccacc gcctcggcgg tcggtgagcg
     3961 acagatgttg cctgtacaca cgaacaggat cctcttcatc ccctcccctc ctcttattgt
     4021 tgtttacacg ctgccgtgct ggtcggcgcc gaaggcgcgc tcgcgcagct tgaagagctc
     4081 gtcgcgcgcc gcagcggcct tctcgaactc caggttgcgg gcatgctcct gcatctcctt
     4141 ctcgaggcgc ttgatcgcgc gcgccagcga cttctcgtcc atcgccgcgt agtcgccgcc
     4201 cttctccgcc acacgcgcga cgtcgcgctt ggcgccatcg gcatcgtaca ccccgtcgat
     4261 gatgtccttg atgcgcttgg tcaccgactt cggcacgatg ccgttggcct cgttgaaggc
     4321 aatctgcttc tgccgccggc gctcggtctc gccgatggcc gccttcatcg agtcggtgac
     4381 gcggtcggcg tagaggatgg cggtgccgtg gaggtggcgc gcggcgcggc cgatggtctg
     4441 gatcagcgaa cgctccgagc gcaggaagcc ctccttgtcc gcatccagga tcg
//
LOCUS       DAOTIN010000194         4457 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_23197_length_4457_cov_9.343253, whole genome shotgun sequence.
ACCESSION   DAOTIN010000194 DAOTIN010000000
VERSION     DAOTIN010000194.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 4457)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4457)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4457
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_23197_length_4457_cov_9.343253"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..684
                     /gene="sufC"
                     /locus_tag="P5537_16405"
     CDS             <1..684
                     /gene="sufC"
                     /locus_tag="P5537_16405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004369369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HRV79670.1"
                     /translation="PNGSGKSTLAQVLAGRETFTVTDGSVDWDGTDLLALPAEERARA
                     GLFLAFQYPVEIPGVSNAYFLKAAVNAVRRHRGLPEYDAMDFLSRVKAEMKAVGMKEE
                     FLYRSVNEGFSGGEKKRNEVLQMALLEPRLAVLDETDSGLDIDALKIVAEGVNRLRSP
                     ERSMIVITHYQRLLDYIVPDKVHVLSQGRIVRSGGRELALELEEHGYGWINAAQGGKA
                     GGTSVGARP"
     gene            681..2117
                     /gene="sufD"
                     /locus_tag="P5537_16410"
     CDS             681..2117
                     /gene="sufD"
                     /locus_tag="P5537_16410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HRV79671.1"
                     /translation="MSAIDFWLGRHRDTAAGLPGADLPWLVRLREDAIDRFADEGWPT
                     TRRENWRHTSLAFMAQQALAVREAVAPETVVAALRARYQAARGAAQDAAQQGAKSAPQ
                     SAPGSAPELAPELAPELAPELAHNDGHWVVFVDGHFAPALSAIGGLPGGVRIGSLADA
                     LAQTPEKVEAAFGQAGDGEAPAALNAALAADGAWIRLARGSMVEAPIHLVFIAATAAD
                     QHLRNLVVADAGAQATIVEHYPAGAAGSTLTTAVTRVLAAQDSHVTHLKLQQEAPEAI
                     HLTTIEAEQARGAVFTSHSLSFGARLARNDIRTRLAGEGAEALLNGLYHADGRRHVDH
                     HTRIDHARPQGTSREFYRGLLDGSARGVFTGRILVAQDAQRTDAMQRCDNLLLSRLAE
                     ADARPELEIYADDVKCAHGATVGQLDEDALFYLRSRGVDAVHARQLLTYAFAAEVLER
                     IAHAPLRALGRAALLERLPEGARLEELL"
     gene            2114..3373
                     /locus_tag="P5537_16415"
     CDS             2114..3373
                     /locus_tag="P5537_16415"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004311650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HRV79672.1"
                     /translation="MNAPRDPGAQTPILDLAADFPILARPVHGRRLAYLDNGATTQKP
                     AAVIEAEARFYRESNANIHRGVHWLSQHATELYDGARATVQRFLNAARADEIVFTRGT
                     TEAINLVAQSWGRPRLAAGDEILLSTMEHHSNIVPWQLVCEQTGAVLKVIPVQDNGEL
                     DMEAFEGLLGERTRLLAITHVSNALGTVNPVAAMTRRAHELGALVLVDGAQAVAHQAV
                     DVQAIGCDFYAFSGHKLYGPTGIGALYGRAELLRHMPPWQGGGDMIRTVAFDNTTFAP
                     PPQRFEAGTPNIAGAIALAAAIDYMQGVGLARIHAHEQALLEYGTRALQDIPGVRLVG
                     TAREKAGILSFLVDGIHPHDLGTILDSEGVAIRAGHHCAMPLMTRFGIPGTARASLGL
                     YNGLADLDALVAAIHKAQALFGTRRQA"
     gene            3370..3834
                     /locus_tag="P5537_16420"
     CDS             3370..3834
                     /locus_tag="P5537_16420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004311652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HRV79673.1"
                     /translation="MSDMQDSLRELYQEVIFDHNRNPRNYRPLPAASHHADGHNPLCG
                     DQLTVYLQVEDGIVREASFVGHGCAISTASASLMTEAVKGKPVAEVEALFRDVHALLT
                     EGREAADPARDFGKLEVLSGVKEFPARVKCATLAWHTLHNALVGEHETAHTE"
     gene            3856..4425
                     /gene="sufT"
                     /locus_tag="P5537_16425"
     CDS             3856..4425
                     /gene="sufT"
                     /locus_tag="P5537_16425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative Fe-S cluster assembly protein SufT"
                     /protein_id="HRV79674.1"
                     /translation="MGDHYGETDSRVLQRDCAAVSVPWGKAETLPEGAYALVTQRLGG
                     SITVMCGGNLYRIDERNADALGLEPQLAATPPVAADGEQTAESVEQAAWAQLATCYDP
                     EIPIDIVNLGLVYACTAEALPDGRFHIAAAMTLTAPGCGMGTLIADEARDKLLQIPGV
                     AEAEVKLVWDPPWSREMMSEAARLEMGMF"
BASE COUNT          692 a         1703 c         1496 g          566 t
ORIGIN      
        1 cccaacggct cgggcaagag cacgctcgcc caggtgctgg ccgggcgcga gaccttcacc
       61 gtcaccgacg gcagcgtcga ctgggacggc accgacctgc tcgccctgcc cgccgaggag
      121 cgcgcgcgcg ccgggctctt cctcgccttc cagtacccgg tcgagatccc gggcgtgtcc
      181 aatgcctact tcctcaaggc cgcggtcaac gcggtgcgcc gccaccgcgg cctgccggaa
      241 tacgacgcga tggacttcct gtcgcgcgtg aaggccgaga tgaaggcggt cggcatgaag
      301 gaggagttcc tctaccgctc ggtgaacgaa ggcttctcgg gcggcgagaa gaagcgcaac
      361 gaggtgctgc agatggcgct gctcgagccc aggctcgcgg tgctcgacga gaccgactcg
      421 gggctcgaca tcgacgcgct gaagatcgtc gccgaggggg tcaatcgcct gcgctcgccc
      481 gagcgctcga tgatcgtcat cacccactac cagcgcctgc tcgactacat cgtgcccgac
      541 aaggtgcacg tgctgtcgca gggccgcatc gtgcgttcgg gtggacgcga gctcgcgctc
      601 gagctggaag agcacggcta cggctggatc aacgcggcgc agggcggcaa ggccggcggc
      661 acgtccgtgg gagcgcggcc atgagcgcga tcgacttctg gctcggacgc catcgcgaca
      721 ccgccgccgg gctacccggc gccgacctgc cctggctcgt ccgcctgcgc gaagacgcga
      781 tcgaccgctt cgccgacgaa ggctggccga cgacgcggcg cgagaactgg cgccacacct
      841 cgctcgcctt catggcgcag caggcgctgg cggtgcgcga ggcggttgcc cccgagacgg
      901 tcgtggcggc gctgcgcgca cgctaccagg cggcacgtgg cgccgcgcaa gacgccgcgc
      961 agcagggcgc gaagtcggcc ccgcaatcgg caccgggatc ggccccggaa ttggccccgg
     1021 aattggcccc ggaattggcc ccggaattgg cccataacga cggccactgg gtggtcttcg
     1081 tggatgggca cttcgccccc gcgctgtccg ccatcggcgg gcttcccggc ggcgtgcgca
     1141 tcggcagcct cgcggacgcg ctcgcccaga cccccgaaaa ggtcgaggcc gccttcggcc
     1201 aggccggcga cggcgaggca cccgccgcgc tcaacgccgc gctggccgcc gacggcgcct
     1261 ggatccgcct ggcgcgcggc agcatggtcg aagcaccgat ccacctcgtc ttcatcgccg
     1321 cgaccgccgc cgaccagcac ctgcgcaacc tcgtcgtcgc cgatgccggc gcgcaggcga
     1381 ccatcgtcga gcactacccg gccggcgccg ccggcagcac gctgaccacc gccgtcaccc
     1441 gcgtgctcgc cgcgcaggac agccacgtca cgcacctcaa gctgcaacag gaggctcccg
     1501 aggccatcca cctgacgacg atcgaggccg agcaggcgcg cggcgcggtg ttcacctcgc
     1561 actcgctgtc cttcggcgcg cgcctggcac gcaacgacat ccgcacccgg ctcgccggcg
     1621 agggcgccga ggcgctattg aacggcctct atcacgccga cggccgccgc catgtcgacc
     1681 accacacccg catcgaccac gcccgcccgc agggcacgag ccgcgagttc taccgcggcc
     1741 tgctcgacgg cagcgcgcgc ggcgtgttta ccggccgcat cctggtcgcc caggacgccc
     1801 agcgcaccga cgccatgcag cgctgcgaca acctgctgct gtcccgcctg gccgaggccg
     1861 acgcccgccc cgagctcgag atctacgccg acgacgtcaa gtgcgcgcac ggcgccaccg
     1921 tgggccagct cgacgaggac gccctcttct acctgcgcag ccgcggcgtc gatgcggtgc
     1981 acgcccgcca gctgctgacc tacgccttcg ccgccgaggt gctcgagcgc atcgcccacg
     2041 cgccgctgcg cgcgctcggc cgcgccgcgc tgctcgaacg cctgcccgaa ggcgcccgac
     2101 tggaggaact gctgtgaacg ctccgcgcga tcccggcgcg cagacgccca tcctggacct
     2161 cgccgccgac ttccccatcc tggcgcgacc ggtgcatggc cgccgcctgg cctacctcga
     2221 caacggcgcc accacacaga agccggcggc ggtgatcgag gccgaggcgc gcttctaccg
     2281 cgagtccaac gccaacatcc accgcggcgt gcactggctg tcgcagcacg ccaccgagct
     2341 ctacgacggc gcacgcgcca cggtgcagcg cttcctcaac gccgcgcgcg ccgacgagat
     2401 cgtgttcacc cgcggcacca ccgaggcgat caacctggtg gcgcagagct ggggccgacc
     2461 gcgcctggcc gcaggcgacg agatcctgct cagcaccatg gagcaccact ccaacatcgt
     2521 gccctggcag ctcgtgtgcg agcagaccgg cgcggtgctc aaggtgatcc cggtgcagga
     2581 caacggcgag ctcgacatgg aagccttcga gggcctgctc ggcgagcgca cccggctgct
     2641 ggccatcacc cacgtgtcga acgcgctcgg cacggtcaac ccggtggccg cgatgacgcg
     2701 gcgcgcgcac gagctcggcg cgctcgtgct ggtcgatggc gcccaggccg tcgcccacca
     2761 ggcggtggac gtgcaggcga tcggctgcga cttctacgcc ttctccggcc acaagctcta
     2821 cggccccacc ggcatcggcg cgctctacgg tcgcgccgag ctgctgcgcc acatgccgcc
     2881 gtggcagggt ggcggcgaca tgatccgcac cgtcgccttc gacaacacca ccttcgcccc
     2941 accgccgcag cgcttcgagg ccggcacgcc caacatcgcc ggcgcgatcg ccctggccgc
     3001 ggcgatcgac tacatgcagg gcgtcggcct ggcgcgcatc catgcccacg agcaggcgct
     3061 gctggagtac ggcacgcgcg cgctgcagga cattcccggc gtgcgcctgg tcggcaccgc
     3121 gcgcgagaag gcgggcatcc tttccttcct ggtcgacggc attcacccgc acgatctcgg
     3181 caccatccta gactcggagg gcgtggcgat ccgcgccggc caccactgcg cgatgccgct
     3241 gatgacgcgc ttcggcatcc ccggcaccgc acgcgcctcg ctcggcctgt acaacggact
     3301 cgccgacctc gacgcgctgg tcgcggcgat ccacaaggcg caggcgctgt tcggcacgcg
     3361 gaggcaagca tgagcgacat gcaggattcg ctgcgcgagc tgtaccagga ggtgatcttc
     3421 gatcacaacc gcaacccgcg gaactaccgc ccgcttcccg ccgccagcca tcacgccgac
     3481 ggccacaacc cgctgtgcgg cgaccagctc acggtgtacc tgcaggtcga ggacggcatc
     3541 gtgcgcgagg cgagcttcgt cggccacggc tgcgcgatct ccaccgcctc ggcctcgctg
     3601 atgaccgagg cggtcaaggg caagccggtc gcggaggtcg aggcgctgtt ccgcgacgtg
     3661 cacgcgctgc tcaccgaagg ccgcgaggcc gccgacccgg cgcgcgactt cggcaagctc
     3721 gaggtgctct ccggcgtcaa ggagttcccc gcgcgggtca agtgcgccac gctcgcctgg
     3781 cacaccctgc acaacgcgct cgtcggcgag cacgagaccg cacacaccga ataagacctc
     3841 gaggagcacg acatcatggg tgaccactac ggcgaaaccg attcccgcgt gctgcagcgc
     3901 gactgcgcgg cggtgagcgt gccctggggc aaggcggaga cgctccccga gggcgcctac
     3961 gcgctggtga cccagcgcct gggcggctcg atcacggtga tgtgcggggg caacctgtac
     4021 cgcatcgacg agcgcaacgc cgacgcgctc ggcctggagc cgcagctcgc cgccaccccg
     4081 ccggtcgccg cggacggcga gcagaccgca gaaagcgtcg agcaggccgc gtgggcgcag
     4141 ctcgccacct gctacgaccc cgagatcccg atcgacatcg tcaatctcgg cttggtctac
     4201 gcctgcaccg cggaggcgct gcccgacggc aggttccaca tcgccgccgc gatgaccctc
     4261 accgcgcccg gctgcggcat gggcaccctg atcgccgacg aggcgcgtga caagctgctg
     4321 cagatccccg gcgtcgccga ggccgaggtg aagctggtgt gggacccgcc gtggagccgc
     4381 gagatgatga gcgaggccgc gcggctggag atggggatgt tctgagggtc gcacgtggcc
     4441 gccccaccga cgccaat
//
LOCUS       DAOTIN010000195         4401 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_23560_length_4401_cov_7.905200, whole genome shotgun sequence.
ACCESSION   DAOTIN010000195 DAOTIN010000000
VERSION     DAOTIN010000195.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 4401)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4401)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4401
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_23560_length_4401_cov_7.905200"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(190..984)
                     /locus_tag="P5537_16430"
     CDS             complement(190..984)
                     /locus_tag="P5537_16430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV79675.1"
                     /translation="MLKATDLRLTFNPGTPIETQALRGMSLEIPTGQFVTVIGSNGAG
                     KSTFLNAVSGEQRVDSGTIEIDGIDMTRQPVWGRARHVARVFQDPLAGTCEDLTIEEN
                     MALAKMRGERRGFSFAVKPALREEFRAQLSTLGLGLENRLSDRIGLLSGGQRQAVSLL
                     MAALQPSRLLLLDEHTAALDPRTAAFVLELTVRIVAEHKLTTMMVTHSMRQALDVGQR
                     TVMLHQGRVVLDVSGKEREGLDVHHLLDMFEKVRGEKLDDDALLLG"
     gene            complement(986..1876)
                     /locus_tag="P5537_16435"
     CDS             complement(986..1876)
                     /locus_tag="P5537_16435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV79676.1"
                     /translation="MSLYTLLGALEIGLIFSLVALGVYISFRLLRFPDLTVDGSFPLG
                     GAVAATMIAAGYDPFTATIAATLAGAVAGLVTGWLNVSLKIMDLLASILMMIALYSIN
                     LRVMGKPNVPLITEPTVFNLLQPEALADYVFRPLLLVFVVLAVKLALDAYFSTQSGLA
                     IRATGSNARMARAQGVNTGMAILAGMALSNALVGLAGALFAQTQGGADISMGVGTIVI
                     GLAAVIVGESLLPSRKLYLATIAVIVGAIVYRFFIALALNSDFIGLQAQDLNLVTAVL
                     VTVALVVPRLRAHWSGKKGA"
     gene            complement(1976..2947)
                     /locus_tag="P5537_16440"
     CDS             complement(1976..2947)
                     /locus_tag="P5537_16440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HRV79677.1"
                     /translation="MSFPLSRKALFGALALAFVAAMPVHAQQKSVAITAIVEHPALDS
                     VRDGVKEALAAAGYEDGKNLKWQYQSAQGNTGTAAQIARKFVGDKADVIVAIATPSAQ
                     AVAAATKDIPLVYSAVTDPVVAKLVPSMAPSGTNVTGVSDALELGKQIELIKRVAPAA
                     KRVGIVYNPGEANSVVVVEQLRELLPKHGLSLVEAAAPRSVDVGSAARSLIGKADVFY
                     TSTDNNVVSAYEALVKVGMDAKIPLVAADTDSVARGAVAAYGMDYKALGVQTGEIVVR
                     ILKGEQPGAIASETSNKLSLHVNPGAAQKQGITLAEDLVKSASKVVQ"
     gene            3143..>4401
                     /locus_tag="P5537_16445"
     CDS             3143..>4401
                     /locus_tag="P5537_16445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HRV79678.1"
                     /translation="MLPAYAELHCLSNFSFQRGASHPEELVAQAAAFGYRAIALTDEC
                     SFAGVVRAWRALQALPEAGRPRLIVGCELRLADGPCLVLLAADRAGYGRLSRLVTQAR
                     RSAEKGRYHLTRAMLDAVREGEGEGEGAAAEALPGCLALLIPPDGFPPPDAPLDAAIA
                     LRSEARWLAKRFPGRAWIAHTPRLDGRDPARLHWILRIAQAAGIRAVAAGGALMHEAT
                     RRPLADVMTALRLHCSVAEAGLALAPNAELRLHERATLARRHPPELLAETLAVAARCR
                     FGLDELRYEYPAELVPADETPASWLRRLVEGGLAWRYGEAASDRRAAAPTAIAAAPPP
                     AEDPAPPTVRAQIEHELALIAELGYEPYFLTVHDIVRFAREAGILCQGRGSAANSVVC
                     WALGITEVDPQLGIMLVERFISRERDEP"
BASE COUNT          655 a         1581 c         1523 g          642 t
ORIGIN      
        1 acccgccgtt cgcgttggag gaaatttctc agccgctatg tctcttgatg gccgaaataa
       61 accgcggaca caatctcgaa aatcttcatc acaaacgcaa aatttcgaga catgcccggg
      121 tgattcgagg ccgccgtacc ccaccttcgc gttagccacc ggcacggcgc gccccgcaac
      181 acccacgcgc taccccagca gcagcgcgtc gtcgtcgagc ttctcgccgc gcaccttttc
      241 gaacatgtcg agcaggtgat gcacgtccag cccctcgcgc tccttgcccg acacatccag
      301 caccacccgc ccctgatgca gcatcacggt acgctggccg acatcgagcg cctggcgcat
      361 cgagtgcgtg accatcatcg tcgtgagctt gtgctcggcg acgatgcgca cggtgagttc
      421 cagaacgaaa gccgcggtgc gcgggtcgag cgccgcggtg tgctcgtcga gcagcagcag
      481 ccgcgagggc tgcagcgccg ccatcagcag gctcaccgcc tggcgctggc cgcccgagag
      541 caggccgatg cggtccgaca ggcggttctc caggccgagg ccgagggtgg acaactgcgc
      601 gcgaaactcc tcgcgcagcg ccggcttgac cgcgaaggag aagccgcggc gctcgccgcg
      661 catcttggcg agcgccatgt tctcctcgat ggtcaggtct tcgcaggtgc cggcgagcgg
      721 gtcctggaac acgcgcgcga cgtggcgggc gcgcccccac accggctgcc gggtcatgtc
      781 gatgccgtcg atctcgatcg tgccgctgtc gacgcgctgc tcacccgaca cggcgttgag
      841 gaaggtcgac ttgccggcgc cgttggagcc gatgacggtg acgaactgcc cagtcgggat
      901 ctcgagcgac atgccgcgca gggcctgggt ctcgatcggc gtgccgggat tgaaggtgag
      961 gcgcaggtcg gttgccttca gcatgtcagg ctcctttctt gccggaccag tgcgcgcgca
     1021 ggcgcggcac caccagcgcg accgtcacca gcaccgcggt gacgaggttg aggtcctgcg
     1081 cctgcaggcc gatgaagtcc gaattgagcg cgagcgcgat gaagaagcga tacacgatgg
     1141 caccgacgat caccgcgatg gtcgccaggt agagcttgcg cgagggcagc aggctctcgc
     1201 ccacgatcac cgcggcgagg ccgatgacga tcgtgcccac gcccatcgag atgtcggcgc
     1261 cgccctgggt ctgcgcgaac agcgccccgg ccaggcccac cagcgcgttc gacagcgcca
     1321 tgccggcgag gatcgccatg ccggtattga cgccctgcgc ccgcgccatg cgcgcgttcg
     1381 agccggtggc gcggatcgcc aggccgctct gggtggagaa ataggcatcg agcgcgagct
     1441 tgaccgccag caccacgaag accagcagca gcgggcggaa cacgtagtcg gcgagcgcct
     1501 cgggctgcag caggttgaac acggtcggct cggtgatcag cggcacgttg ggcttgccca
     1561 tcacgcgcag gttgatcgag tacagcgcga tcatcatcag gatgctggcg agcaggtcca
     1621 tgatcttgag gctgacgttg agccagccgg tgaccaggcc ggcgaccgcg ccggccagcg
     1681 tcgccgcgat ggtcgcggtg aaggggtcgt agccggcggc gatcatggtc gcggcgacgg
     1741 caccgccgag cgggaagctg ccatccacgg tgagatcggg aaagcgcagc agccggaagg
     1801 agatgtacac gccgagggcg acgaggctga agatcaggcc gatctccagc gccccgagca
     1861 aggtgtagag cgacattggg ggattaccgt tggtgaggat cgagcggggc gtgcgccggg
     1921 gcgacgtccc gcgcggccgg gcttggacgg ccgcgcgagg ctgcggacga tccgcttact
     1981 ggacgacctt ggaggccgac ttgacgaggt cctcggcgag ggtgatgccc tgcttctgcg
     2041 ccgcacccgg gttcacgtgc agcgacagct tgttgctggt ctcggaggcg atcgcgccgg
     2101 gctgctcgcc cttgaggatg cgcaccacga tctcgccggt ctgcacgccg agcgccttgt
     2161 agtccatgcc gtaggccgcg accgcgccgc gcgccacgct gtcggtgtcg gccgccacca
     2221 gcgggatctt ggcgtccatg ccgaccttga ccagggcctc gtaggccgac acgacgttgt
     2281 tgtcggtgct ggtgtagaac acgtcggcct tgccgatcag gctgcgcgcc gccgagccga
     2341 cgtccaccga gcgcggcgcc gcggcctcga ccaggctcag gccgtgcttg ggcagcagtt
     2401 cgcgcagctg ctcgaccacg acgaccgagt tggcctcacc cgggttgtag acgatgccga
     2461 cgcgcttggc agccggcgcg acgcgcttga tcagctcgat ctgcttgccg agctcgagcg
     2521 catccgacac cccggtgacg ttggtgccgg aaggcgccat cgagggcacc agcttggcca
     2581 ccaccgggtc ggtcaccgcg gaatacacca gcgggatgtc cttggtcgcg gcggcaacag
     2641 cctgcgccga gggggtggcg atcgcgacga tgacgtcggc cttgtcgccg acgaacttgc
     2701 gcgcgatctg cgcggccgtg cccgtgttgc cctgcgcgct ctggtactgc cacttgaggt
     2761 tcttgccgtc ctcgtagccg gccgcggcca gcgcctcctt gaccccgtcg cgcaccgaat
     2821 cgagcgcggg gtgctcgacg atcgcggtga tggcaaccga cttctgctgg gcgtgaaccg
     2881 gcatcgccgc cacgaacgcg agcgccagcg caccgaacag ggccttgcgg gacaggggga
     2941 aggacatgga ggtctccttt gtggccgtgc ggccggaaat tcttcgagaa aggggtttgg
     3001 ccggcaccgt ggccggcagg gtgtcgtcaa gagcgcaagt ttaacagcag gtccggatta
     3061 cgcgattgcg gtggacccgc aatcgccggg gcacgctccg aaccggcttg ctcgaaagac
     3121 tgtatttttt tacagtctac ccatgcttcc cgcctacgcc gaactccact gcctgagcaa
     3181 cttcagcttc cagcgcggcg cctcgcaccc cgaggagctc gtcgcgcagg cggcggcctt
     3241 cggctaccgc gcgatcgcgc tcaccgacga gtgctccttc gccggcgtgg tgcgcgcctg
     3301 gcgcgcgctg caggccctgc ccgaggccgg ccgcccgcgc ctgatcgtcg gctgcgagct
     3361 gcgcctcgcc gacggcccct gcctcgtgct gctcgccgcc gaccgcgccg gctacggccg
     3421 gctctcgcgc ctggtcaccc aggcccggcg cagcgccgaa aagggccgct accacctcac
     3481 gcgcgcgatg ctcgacgccg tccgcgaggg cgagggcgag ggcgagggcg ccgccgccga
     3541 agccctgccc ggctgcctgg cgctgctgat cccgcccgac ggcttcccgc cgccggacgc
     3601 cccgctcgac gcggccatcg ccctgcgcag cgaggcgcgc tggctggcga agcgcttccc
     3661 cgggcgcgcc tggatcgccc acaccccgcg cctggacggg cgcgaccccg cccgcctgca
     3721 ctggatcctg cgcatcgccc aggccgccgg catccgcgcg gtggccgccg gcggggcgct
     3781 gatgcacgag gccacgcggc gcccgctcgc cgacgtgatg accgcactgc gcctgcactg
     3841 cagcgtggcc gaggccggcc tggcgctcgc acccaacgcc gagctgcgcc tgcacgagcg
     3901 cgccaccctc gcccgccgcc acccccccga gctgctcgcc gagaccctgg cggtggctgc
     3961 gcgctgccgc ttcggcctcg acgagctgcg ctacgagtac cccgccgagc tcgtccccgc
     4021 ggacgagacc ccggcgagct ggctgcgccg gctggtcgag ggcgggctgg cctggcgcta
     4081 cggcgaggcc gccagcgatc gccgcgcggc ggcgcccact gccatcgccg ctgcgccgcc
     4141 gccggccgaa gaccccgccc cgcccacggt gcgcgcgcag atcgagcacg agctcgccct
     4201 catcgccgag ctcggctacg agccctactt cctcaccgtg cacgacatcg tgcgcttcgc
     4261 ccgcgaggcc ggcatcctgt gccagggccg cggctcggcg gccaactcgg tggtgtgctg
     4321 ggcgctcggc atcaccgagg tcgacccgca gctggggatc atgctggtcg agcgcttcat
     4381 ctcgcgcgag cgcgacgagc c
//
LOCUS       DAOTIN010000196         4221 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_24885_length_4221_cov_8.795487, whole genome shotgun sequence.
ACCESSION   DAOTIN010000196 DAOTIN010000000
VERSION     DAOTIN010000196.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 4221)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4221)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4221
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_24885_length_4221_cov_8.795487"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1360
                     /locus_tag="P5537_16450"
     CDS             <1..1360
                     /locus_tag="P5537_16450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="choice-of-anchor I family protein"
                     /protein_id="HRV79679.1"
                     /translation="LVANEGEPNDDYSIDPEGSISVIDVSTPSAPVARSAGFAAFNGQ
                     EKALRAQGVRIYGPGASAAQDFEPEYIAVSADGATAWATLQENNALARIDVATATVEA
                     ILPLGDKDHGLDANALDASDDDKKAVIQAWPGVRGLYLPDAIASYTHQGRTLLVTANE
                     GDARTWGEGDDAYWDGDASKGFVEEFRVKHLTNAKGWSGRKGDDLPPQLDALADGGLL
                     DPTVFAYCGAVAGSPGQCRDDDQLGRLNITWTMGYRQDADGRPILFDTAGNENPAGTR
                     LMYDTLYAFGGRSFSIRDEDGKLVWDSGAEIERFLASDECKLGAARNLPCADWFNANH
                     EEGDTLDNRSDNKGPEPEGVALGRIGDKTFAFVGLERMGGVLVYDITDPQAPTRVDYL
                     NPREDWTTEDPATVLANVGDLGPEGLHFIPAKDSPNAKPLLLVGNEVSGTTAVYQLNL
                     SY"
     gene            complement(1344..3755)
                     /locus_tag="P5537_16455"
     CDS             complement(1344..3755)
                     /locus_tag="P5537_16455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HRV79680.1"
                     /translation="MPPTMPDDSTAEFSASRRSIPGFCGLCKSRCGSRMVVEDGRLVA
                     QLPDPAHPTGRAQCVKGRAAPELVYDPQRVLRPLLRTRPKGDAEPGWREISWDEALGR
                     VAQALLRVRAESGPEAVAFAIATPSGTPIADDIRWIERLANAFGSPNVANGTEICNWH
                     KDFTHQLTFGRGIATPDFAHSRCIVLWGHNPRDTWLANSLAIRAARKAGAKVVVVDPR
                     KAGFAADADLWLRVRPGSDGALALGVVRVMLARGWFDAAFVRDFSNAPLLVRGDDGRL
                     LRAGELAAPPAGAGGDDLVAIAADGGWIACGRGVRGSAGSGAEPVLTGSVDAHLADGR
                     VVRCETVFARFEQACADYTPERVAALCWIEPAQVEALAGLLHEAGPAVSYYCWAGVCQ
                     HTNATQTDRAIATLMALTGSFDAPGGNVAFTPAPANDASGKDLLGAAQRARCIGLERS
                     RLGPARLGLIGSDALWDAILEERPYPIRALVGFGRDFLLNHADAERAAEALAALEFCV
                     YADLTLTPTAALADIVLPICTPWEREALRVGFEGSQAAESWVQLRPAAIAPLGDSRAD
                     AWVVFALAQRLGLGEHFWGGDLEAGLAHVLAPTGLTLETLRAHPGGLARPAPTRYRKQ
                     VEEGFRTPSGRIELYSETLLEHGEPPLPRFEEPADSPFGAASAAFPLVMTTAKLRHFR
                     HGQDRQAPSLRRHSPEPSVHLHPDAARARGIAEGDPVRVRTANGAIRMQARFDAALDA
                     RVVWVEYGWWQPGTAGAADGYDARSEDGANYSRLVSDRRVDPVAGSQPLRSGLCEIEP
                     LSSSG"
     gene            3845..>4221
                     /locus_tag="P5537_16460"
     CDS             3845..>4221
                     /locus_tag="P5537_16460"
                     /inference="COORDINATES: protein motif:HMM:NF017868.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcyclotransferase"
                     /protein_id="HRV79681.1"
                     /translation="MERLFVYGTLGPGRPNEHVMQKIGGSWQPASVRGRLVHAGWGFE
                     RSGFPALVLDEHGDEIAGHVFVSPNLAAHWPALDAFEGEDYVRELTRAILADGTEVEA
                     CVYALAEAKRPRSSEHSLGGPSRT"
BASE COUNT          634 a         1603 c         1470 g          514 t
ORIGIN      
        1 gctggtcgcc aacgagggcg agccgaacga cgactactcg atcgaccccg agggctcgat
       61 cagcgtcatc gacgtctcca ccccctcggc gccggtcgcg cgcagcgccg gttttgccgc
      121 cttcaacggc caggagaagg ccctgcgcgc ccagggcgtg cgcatctacg gccccggcgc
      181 gagcgccgcg caggacttcg agcccgagta catcgccgtg tccgccgatg gtgccaccgc
      241 ctgggccacg ctgcaggaga acaacgcgct cgcccgcatc gacgtcgcca cggccacggt
      301 cgaggcgatc ctgccgctcg gcgacaagga ccacggtctc gatgcgaacg cgctcgacgc
      361 ctccgacgac gacaagaagg ccgtcatcca ggcctggccg ggcgtgcgcg gcctctacct
      421 gcccgacgcc atcgcgtcgt acacccacca gggccgcacc ctgctggtca ccgccaacga
      481 gggcgacgcg cgcacctggg gcgagggtga cgacgcctac tgggatggcg acgccagcaa
      541 gggcttcgtc gaggagttcc gcgtcaagca cctcaccaat gccaagggct ggtccggccg
      601 caagggcgac gacctgccgc cgcagctcga cgcgctcgcc gatggcggcc tgctcgaccc
      661 gacggtcttc gcctactgcg gcgcggtcgc cggcagcccc ggccagtgcc gcgacgacga
      721 ccaactcggc cgcctcaaca tcacctggac gatgggctat cgccaggacg ccgacggaag
      781 gccgatcctc ttcgacaccg ccggcaacga gaacccggcc ggcacccgcc tgatgtacga
      841 cacgctctat gccttcggcg ggcgctcgtt ctcgatccgc gacgaggacg gcaagctggt
      901 gtgggactcg ggcgccgaga tcgagcgctt cctcgccagc gacgaatgca agctcggcgc
      961 cgcgcgcaac ctcccctgcg ccgactggtt caacgccaac cacgaggaag gcgacacgct
     1021 cgacaaccgc agcgacaaca agggccccga gcccgaaggc gtcgcgctcg gacgcatcgg
     1081 cgacaagacc ttcgccttcg tcggcctcga gcgcatgggc ggcgtgctgg tgtatgacat
     1141 caccgacccg caggcgccga cgcgcgtgga ctacctgaac ccgcgcgagg actggaccac
     1201 ggaagacccc gcgaccgtgc tcgcgaacgt cggcgacctc ggccccgaag gcctgcactt
     1261 catccccgcc aaggattcgc ccaacgccaa gccgctgctg ctggtcggca acgaggtcag
     1321 cggcaccacg gcggtgtacc agctcaacct gagctactga gcggctcgat ctcgcacagc
     1381 cccgagcgca ggggctgcga gccggcgacg ggatcgacgc ggcggtcgga gacgaggcga
     1441 ctgtagttcg ctccgtcctc cgagcgcgcg tcatagccgt ccgcggcgcc cgccgtgccc
     1501 ggctgccacc agccgtactc cacccacacc acgcgcgcat cgagcgccgc atcgaagcgc
     1561 gcctgcatgc ggatggcgcc gttggcggtg cgcacccgca ccgggtcgcc ctcggcgatt
     1621 ccgcgcgcac gcgccgcgtc cggatgcaga tgcaccgagg gctcgggcga gtgccggcgc
     1681 agcgagggcg cctggcggtc ctgcccgtgg cggaagtggc gcagcttggc ggtggtcatc
     1741 accagcggaa acgccgcaga agcggccccg aacggcgagt cggccggctc ctcgaagcgc
     1801 ggcagcggcg gctccccgtg ttcgagcagg gtctcggaat acaactcgat cctgccgctc
     1861 ggcgtgcgga agccctcctc cacctgcttg cgatagcggg taggcgcggg tcgcgcgagc
     1921 ccgcccgggt gcgcgcgcag cgtctcgagg gtgagcccgg tgggcgcgag cacatgagcc
     1981 agcccggcct ccaggtcgcc gccccagaag tgctcgccca agcccagccg ctgcgcgagc
     2041 gcgaacacca cccaggcatc cgcgcggctg tcgccgagcg gcgcgatcgc cgccgggcgc
     2101 agctgcaccc aggactccgc cgcctggctg ccctcgaagc ccacgcgcag cgcctcgcgc
     2161 tcccacggcg tgcagatcgg cagcacgatg tcggccagcg ccgcggtggg ggtgagcgtg
     2221 aggtcggcgt agacgcagaa ctcgagcgcg gccagcgcct cggcggcgcg ttcggcatcc
     2281 gcatggttga gcaggaagtc gcggccgaag ccgaccaggg cgcggatcgg gtacggccgc
     2341 tcctccagga tcgcgtccca cagcgcgtcc gagccgatga ggccgagcct ggccgggccg
     2401 agccgcgaac gctcgagccc gatgcagcgc gcgcgctgcg cagcgccgag caagtccttg
     2461 ccgctggcgt cgttcgccgg cgcgggggtg aacgcgacgt tgccgcccgg cgcgtcgaag
     2521 ctgccggtga gcgccatcag cgtggcgatg gcgcggtcgg tctgggtggc gttggtgtgc
     2581 tggcacacgc cggcccagca gtaatacgac accgccggcc cggcctcgtg gagcaggccg
     2641 gcgagcgcct ccacctgcgc gggctcgatc cagcacagcg cggcaacgcg ctcgggcgtg
     2701 tagtcggcac aggcctgctc gaagcgcgcg aacacggtct cgcagcgcac cacccgcccg
     2761 tcggccagat gcgcatccac actgcccgtc agcacgggct ccgccccgct gcccgccgac
     2821 ccgcgcaccc ctcggccaca ggcgatccag ccgccatccg ccgcgatcgc gacgaggtcg
     2881 tcgccccccg cccccgccgg cggcgcggca agctcgcccg cgcgcagcag gcgcccgtcg
     2941 tcgccacgca cgagcagcgg cgcgttgctg aaatcgcgca cgaaggctgc gtcgaaccag
     3001 ccccgcgcca gcatcacccg caccaccccg agcgcgagcg ccccgtccga accgggccgc
     3061 acgcgcagcc acaggtcggc gtcggctgcg aagcccgcct tgcgcggatc gaccaccacc
     3121 accttcgccc ccgccttgcg cgccgcgcgg atcgccagcg agttggccag ccaggtgtcg
     3181 cgcgggttgt ggccccacag cacgatgcag cggctgtgcg cgaagtccgg cgtggcgatg
     3241 ccgcggccga aggtgagctg gtgggtgaag tccttgtgcc agttgcagat ctcggtgccg
     3301 ttggccacgt tggggctgcc gaaggcgttg gccaggcgct cgatccagcg gatgtcgtcg
     3361 gcgatcggcg tgccgctcgg cgtcgcgatc gcgaacgcca ccgcctccgg cccggactcc
     3421 gcgcgcaccc gcaagagtgc ctgcgccacc cggccgagcg cctcgtccca cgagatctcg
     3481 cgccagcccg gttcggcgtc gcccttgggc cgcgtgcgca agagcgggcg cagcacgcgc
     3541 tgcgggtcgt aaaccagctc cggcgccgcc cgccccttca cgcactgcgc gcgcccggtg
     3601 ggatgcgccg ggtcgggcag ctgcgccacc agccggccgt cctccaccac catgcgcgag
     3661 ccgcagcgcg acttgcacag gccgcagaag ccggggatgg aacggcgcga ggcggagaat
     3721 tccgccgtgg aatcgtcggg catggtgggc ggcatgacgt tgtggtccaa tcgagggcga
     3781 ggggctcgct ggcgggctct tccatgctag cagcccggcg ccgcacgcca acccggagat
     3841 ttccatggaa cgtcttttcg tctacggcac gctcggcccc gggcgcccaa acgagcacgt
     3901 gatgcagaag atcggcggga gctggcagcc cgccagcgtg cgcggccgcc ttgtccacgc
     3961 cggctgggga ttcgagcgct ccggcttccc cgccctggtc ctcgacgagc acggcgacga
     4021 gatcgccgga cacgtcttcg tgtcgccgaa cctcgccgcc cactggcccg cgctggacgc
     4081 cttcgagggc gaggactacg tgcgcgagct gacgagggcg atcctggccg acggcaccga
     4141 ggtggaggcc tgcgtgtatg cgctggccga ggcgaagcgg ccccggtcgt cggagcactc
     4201 actcggcggg ccgagccgaa c
//
LOCUS       DAOTIN010000197         4097 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_25880_length_4097_cov_8.956705, whole genome shotgun sequence.
ACCESSION   DAOTIN010000197 DAOTIN010000000
VERSION     DAOTIN010000197.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 4097)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4097)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4097
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_25880_length_4097_cov_8.956705"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            3..1121
                     /locus_tag="P5537_16465"
     CDS             3..1121
                     /locus_tag="P5537_16465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HRV79682.1"
                     /translation="MIAVIVPLLAVFANVAMRSGPLAPVKVTVIRVEEGVVAPALFGI
                     GTVEARHAYRIGPTAAGRVKRVDVQVGERVRAGQLLAEMEAVDLADRIRAQEAALGRA
                     EAAVREAEARQGFARAQARRYDQLGSVQAASAELALTRRQELEVAEAGLAAAREERTR
                     ARAEGAALQAQLANLRLLAPVDGVVVLREVEPGTTVVAGQAVVEVVDPATLWVDLRLD
                     QVNAGGLAAGLPARVVLRSRSGEALAGRVLRVEPKADAVTEELLAKVVFDRLPEPMPP
                     LGELAEVSLALPPLPAAPVIPNAAVRREAGVVGVWQVSGEGELRFVPLQLGASDLDGR
                     MQVRAGLAAGDEIVVYSEGALRAGRRIEVVAALDGGAK"
     gene            1118..2323
                     /locus_tag="P5537_16470"
     CDS             1118..2323
                     /locus_tag="P5537_16470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011734096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HRV79683.1"
                     /translation="MISLAGRDILHGWGKFVFTGIGLGLLIGVTLVMAGVYRGMVDDG
                     KALLDNSGADLWVVQRDTLGPYAESSSVQDDLYRSLLGQRGVAGAANITYLTMQVRKG
                     SADVRAMVVGIAAGQPGSTPGWPPYLVAGRQITRGHYEAVADVASGLRLGERVGIRRN
                     QYTVVGLTRRMVSSAGDPMVFIPLKDAQEAQFLKDNDAILQGRRRTEANPALNRPGVP
                     GLLDAVLASQSANPYVNAVLVTLAPGHAPDEVAEAIRRWQRHTVYTRAQMEGILVGKL
                     IATSARQIGMFLVILAVVSAAIVAFIIYTLTMDKIREIAVLKLIGTRNRTIAAMILQQ
                     AVALGLIGFVVGKIAATWSAPFFPKYVLLVPADTVAGFAAVMAICVLASLVSIRLALR
                     VDPAEAIGG"
     gene            2325..3059
                     /locus_tag="P5537_16475"
     CDS             2325..3059
                     /locus_tag="P5537_16475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV79684.1"
                     /translation="MERATSAGKGILIEGLTKRYGKGDTAVDALKGVDMRVAPGEVVG
                     LIGPSGSGKSTLLKCLGAVIDPSAGRMTLGEECIFDAGWKVRDLRALRRDRIGFVFQA
                     PYLIPFLDVTDNVALLPMLAGVPNAEARARALELLGALDISHRAAAMPSQLSGGEQQR
                     VAIARGLVNRPPVILADEPTAPLDSVRAMAVVRILNDLAAQFQTAIIVVTHDEKIIPT
                     FKRIYHIRDGVTHEEAGEGRLVRAAG"
     gene            3229..3726
                     /locus_tag="P5537_16480"
     CDS             3229..3726
                     /locus_tag="P5537_16480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79685.1"
                     /translation="MQSRSSSRLLACGAVAIFAGLLSTAPAVAADSHRHDTHAAVLQL
                     DHGARWQTDAALRTGMEAIRDALARAIPQVHAGRFDAAQYRALAEGVEGQVAYIVQNC
                     KLKPEADEVLHAIIGRLGEGVEVIGGHAAGTKPEEGVVHLAQTLDDYAAHFDHPGWKG
                     LETGH"
     gene            3775..>4097
                     /locus_tag="P5537_16485"
     CDS             3775..>4097
                     /locus_tag="P5537_16485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004366194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HRV79686.1"
                     /translation="MIGERPSSGADAGADTGEARELARARAGDVAAFGALVRRHQERV
                     FRFLHRMLDAREEAMELSQDVFVKAWQALPGWRPEAAFSTWLLQIARNAALDQVRRRQ
                     VVRFAP"
BASE COUNT          549 a         1458 c         1526 g          564 t
ORIGIN      
        1 cgctgatcgc ggtgatcgtc ccgctgctgg cggtgttcgc gaatgtggcg atgcgctcgg
       61 gcccgctcgc cccggtcaag gtgacggtga tccgggtgga ggagggcgtg gtggcgcccg
      121 cgctgttcgg catcggtacg gtggaggcgc gccacgccta ccgcatcggc cccaccgcgg
      181 cgggacgggt caagcgcgtc gacgtgcagg tgggcgagcg cgtgcgcgcc gggcagctgc
      241 tcgccgagat ggaggcggtc gacctcgccg atcgcatccg cgcccaggag gccgcgctcg
      301 ggcgcgccga ggcggcggtg cgcgaggccg aggcgcgcca gggctttgcg cgcgcgcagg
      361 cgcgccgcta cgaccagcta ggcagcgtgc aggcggcgag cgccgagctc gcgctcaccc
      421 gccgccagga gctcgaggtc gccgaggccg gcctcgccgc cgcgcgcgag gagcgcacgc
      481 gcgcccgcgc cgagggcgcc gcgctgcagg cccagctcgc caacctgcgc ctgctcgcgc
      541 cggtcgatgg cgtggtcgtg ctgcgcgagg tggagccggg cactaccgtc gtggccggcc
      601 aggcggtggt ggaggtggtc gatccggcga cgctgtgggt cgacctgcgc ctcgatcagg
      661 tcaatgcggg cggcctcgcc gccggcctgc cggcccgcgt cgtgctgcgc tcgcgcagcg
      721 gcgaggcgct cgccggccgg gtgctgcgcg tggagccgaa ggccgacgcg gtgaccgagg
      781 agctgctcgc caaggtggtc ttcgaccgcc tccccgagcc gatgccgccg ctcggcgagc
      841 tggccgaggt cagcttggcg ctgccgccgc tgccggccgc gccggtgatc cccaacgccg
      901 ccgtgcggcg cgaagccggc gtggtcggcg tgtggcaggt gagcggggag ggcgagctgc
      961 gcttcgtgcc gctgcagctg ggcgcgagcg atctcgacgg gcgcatgcag gtgcgcgcgg
     1021 gcctggcggc gggcgacgaa atcgtcgtct acagcgaagg cgcgctgcgc gccgggcgcc
     1081 gcatcgaggt cgtcgccgcg ctggacggag gcgccaaatg atcagcctcg ccgggcgcga
     1141 catcctgcac ggctggggca agttcgtgtt caccggcatc ggcctggggc tgctgatcgg
     1201 cgtcaccctg gtgatggcgg gcgtgtatcg cggcatggtc gacgacggca aggccctgct
     1261 cgacaacagc ggcgccgacc tgtgggtggt gcagcgcgac acgctcggcc cctatgcgga
     1321 gtcgtccagc gtccaggacg acctctaccg cagcctgctc ggccagcgtg gcgtggcggg
     1381 cgcggccaac atcacctacc tgaccatgca ggtgcgcaag ggcagcgcgg acgtgcgcgc
     1441 gatggtggtc ggtatcgccg ccggccagcc gggatcgacg ccgggctggc cgccctatct
     1501 ggtggccggg cggcagatca cccgcggcca ctacgaggcg gtggccgacg tcgccagcgg
     1561 cctgcgcctc ggcgagcgcg tgggcatccg gcgcaaccag tacaccgtcg tcggcctcac
     1621 gcggcgcatg gtgtcctcgg ccggcgaccc gatggtattc atcccgctca aggacgcgca
     1681 ggaggcccag ttcctcaagg acaacgacgc catcctgcag ggccgccgcc gcaccgaggc
     1741 caaccccgcg ctcaaccgtc ccggcgtgcc cggcctgctc gacgcggtgc tcgcgtcgca
     1801 gagcgccaac ccgtatgtga atgccgtgct ggtcacgctc gcgccgggcc acgcgcccga
     1861 cgaggtggcc gaagccatcc ggcgctggca gcgccacacc gtatacaccc gcgcgcagat
     1921 ggagggcatc ctggtcggca agctgatcgc cacctcggcg cgccagatcg gcatgttcct
     1981 cgtcatcctc gcggtggtga gcgcggccat cgtcgccttc atcatctaca cgctgaccat
     2041 ggacaagatc cgcgagatcg cggtgctcaa gctcatcggc acgcgcaacc gcacgatcgc
     2101 ggcgatgatc ctgcagcagg cggtggcgct cgggctcatc ggcttcgtgg tcggcaagat
     2161 cgccgccacc tggtcggcgc cctttttccc caagtacgtg ctgctggtgc ccgccgacac
     2221 ggtggcgggc ttcgcggcgg tgatggcgat ctgcgtgctc gccagcctgg tgtcgatccg
     2281 gcttgcgctg cgcgtcgatc cggccgaagc gatcggaggc tgacatggag cgagcgacga
     2341 gcgccggcaa gggcatcctg atcgaaggcc tcaccaagcg ctacggcaag ggcgacaccg
     2401 cggtggatgc gttgaagggc gtggacatgc gcgtcgcccc gggcgaggtc gtcggcctca
     2461 tcggcccctc gggttcgggc aagagcacgc tgctgaagtg cctcggcgcg gtcatcgacc
     2521 ccagcgcggg gcgcatgacc ctgggcgagg agtgcatctt cgacgcgggc tggaaggtgc
     2581 gcgacctgcg cgcgctgcgc cgcgacagga tcggcttcgt gttccaggcg ccctacctga
     2641 tccccttcct cgacgtcacc gacaacgtcg ccctgctgcc gatgcttgcc ggggtgccga
     2701 acgccgaggc gcgcgcgcgg gcgctggaac tgctgggcgc gctcgacatc tcgcaccgcg
     2761 ccgcggccat gccctcgcag ctgtcgggcg gcgagcagca gcgcgtcgcc atcgcccgcg
     2821 ggctggtcaa ccgtccgccg gtgatcctcg ccgacgagcc caccgcgccg ctcgacagcg
     2881 tgcgcgcgat ggcggtggtg cgcatcctca acgacctggc cgcgcagttc cagaccgcga
     2941 tcatcgtggt gacccacgac gagaagatca tccccacctt caagcgcatc taccacatcc
     3001 gcgacggggt gacgcacgag gaggccggcg aggggcggct ggtgcgcgcg gccgggtgag
     3061 ggccgctcgt gcggggcggt cggcgggctc cgcgatgccg cacgcgaccg gcggtgcggc
     3121 gcggaaggtt tttgcctcgg ggcatggaac attttgcgcg gcgtttcgtt tcattgtgca
     3181 ggaaggcgat tccgccccct gaacccacga cgaaaggacc tcttcgacat gcaatcccgt
     3241 tcctcctccc gcctgctggc ctgcggcgcc gtcgcgatct tcgccggcct gctgtcgacc
     3301 gccccggccg tggcggccga cagccatcgc cacgacaccc acgccgcggt cctccagctc
     3361 gaccacggcg ccagatggca gactgacgcc gcgctgcgga ccggcatgga ggcgatccgc
     3421 gacgcgctcg cgcgggccat cccgcaggtg cacgccgggc gcttcgatgc cgcgcaatat
     3481 cgtgcgctgg ccgaaggggt cgaagggcag gtcgcctaca tcgtgcagaa ctgcaagctg
     3541 aagcccgagg cggacgaggt gctgcacgcg atcatcggca ggctcggcga gggcgtcgag
     3601 gtgatcggcg gccacgccgc cggaacgaag ccggaggagg gcgtcgtcca cctcgcgcag
     3661 accctcgacg actacgccgc gcacttcgac cacccgggct ggaaagggct ggagacggga
     3721 cactgattcg acagcggcag cggaggacgg cctggtgacg gatctcccgc gcgcatgatc
     3781 ggcgagcgtc cgagcagtgg ggcggacgcg ggcgcggaca cgggcgaggc gcgcgagctc
     3841 gcccgcgccc gcgctggcga cgtggccgcc ttcggcgcgc tcgtccgccg ccatcaggag
     3901 cgcgtgttcc gcttcctcca ccgcatgctc gatgcccgcg aggaggcgat ggagctgagc
     3961 caggacgtct tcgtcaaggc ctggcaggcc ttgcccggct ggcgccccga ggcggccttc
     4021 tccacctggc tgctgcagat cgcgcgcaac gcggcgctcg accaggtgcg ccgccggcag
     4081 gtcgtgcgct tcgcgcc
//
LOCUS       DAOTIN010000198         4062 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_26151_length_4062_cov_8.051909, whole genome shotgun sequence.
ACCESSION   DAOTIN010000198 DAOTIN010000000
VERSION     DAOTIN010000198.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 4062)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4062)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4062
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_26151_length_4062_cov_8.051909"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..422
                     /locus_tag="P5537_16490"
     CDS             <1..422
                     /locus_tag="P5537_16490"
                     /inference="COORDINATES: protein motif:HMM:TIGR03696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="RHS repeat-associated core domain-containing
                     protein"
                     /protein_id="HRV79687.1"
                     /translation="YADHLGSIIGTANSAGTSTAIHSYGPFGEPNVTTGVRFRYTGQQ
                     YLGGLNLYYYKARFYSPALGRFLQTDPIGTADDLNLYAYVGNNPVNFSDPSGLAAEHL
                     KLFAGKVGGSIDNWWDRSVAGFQSAALGDTCGMRPGV"
     gene            593..1162
                     /locus_tag="P5537_16495"
     CDS             593..1162
                     /locus_tag="P5537_16495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin family protein"
                     /protein_id="HRV79688.1"
                     /translation="MKYRPITLAACLLAALFAQFGPAAAADATPAPVEPIAALDVPRY
                     MGTWHEIARYPNWFQKKCAGDSRADYSLLESGEVRVVNRCREADGKVAEAVGLARQLG
                     AADSPRLEVRFAPAWLSFLPMVWGDYWVLDLDPDYRLVAVGEPSREYLWILSRTPTVD
                     ARAYSELLERLAARGFDVGRLVRGEQGGG"
     gene            1434..3758
                     /locus_tag="P5537_16500"
     CDS             1434..3758
                     /locus_tag="P5537_16500"
                     /inference="COORDINATES: protein motif:HMM:NF012772.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HRV79689.1"
                     /translation="MLRRPGLRERLALAMGAFVVSIGVGLTLLMEWRLAAGLRESAQQ
                     RLEYLARDLSSRIGEDLRERRLEVSRLALVLGSSDVLNSRAVQQTLDGLQTRVPAYAW
                     IGLTDARGHVLAGSGGLLSGVDASTRPWFLGGARAEFFGDPHVAKMLGPLLPPERSGE
                     PLRFFDLASPVRRPDGTMVGVLGAHLYTGWIRTVVERTLDSRIEHFPLEVLVADNTGD
                     WLYKTSPDLSATLAALLRESPPTRYLLSSAKVDLPTEAGKLAWTVLVREEASDALAPV
                     YENRRQMGIVVPLLALSLAFATWLIAGRLARPVERVADAARRHAATTGHALDAHVAGG
                     RDEARLLDLTLQRLALRDSLTGLINRSALKQRLALLQRAQAVTASPAPYAVLLLDLDD
                     FHMFNNARGHEHGDQLLRAVAERLRQVACADTVARLGSDEFALLPGLPGGADEDVAAH
                     AQAYAERVVAAFAAPFELPGGAHRCQVSIGIAVVDAAATLPEVALTEAELAMQEAKRL
                     GKGRVVVFDDRLQEGLIAQTRFEQALRAAIPSQLLVLYQPQVDREGRTVGAELLVRWK
                     HTEQGLVSPAMFIPVAEQTGLIVDIGRWVLEQACRQLRAWSDDPLRRHLVLAVNVSSR
                     EFGHPGFVDGVREVLAATGADPARLKIELTESALAADVGEVVARMAALKSLGVRFSLD
                     DFGTGFSSLGYLQRLPLDQLKIDQSFVRGMLTENSSASIVHTVIALGESLGVEVIAEG
                     VETEAQRQALAELGCHHYQGYLFARPVPVEQLPL"
BASE COUNT          559 a         1381 c         1444 g          678 t
ORIGIN      
        1 tctacgccga ccacctgggc agcatcatcg gcacggccaa tagcgccggc accagcaccg
       61 cgatccacag ctacggcccc ttcggcgaac cgaacgtcac caccggcgtg cgcttccgct
      121 acaccgggca gcagtacctg ggtgggctga acctgtacta ctacaaggca cggttctact
      181 cgcccgccct ggggcgcttc ctgcagacgg acccgatcgg cacggccgat gatctgaacc
      241 tgtatgcgta tgtggggaac aacccggtca acttcagtga tccgagcggg ttggcggcgg
      301 agcatctgaa gctctttgca ggcaaggtcg gcgggagcat cgataactgg tgggaccgct
      361 cggtcgcagg cttccagagc gcggcgttag gcgatacgtg tgggatgcgg ccgggtgtct
      421 gaccagcacc gcggccggtg gcaagacgct cgcctaccag tgcgatgcgg cggccaatgc
      481 aatcggcttg acgtgcttta ttttccgttt tctgagacga cccctgcaag gcacgcgaac
      541 cttcgcgctc ctcgcgaagt cgtaccacgc ccattcgcat gcaggatctc cgatgaaata
      601 ccgccccatc acgctggccg cctgtctcct ggcggcgctc ttcgcgcagt tcggccccgc
      661 cgccgcggcc gacgccacgc ccgcgcccgt ggagccgatc gccgcgctcg atgtgccgcg
      721 ctacatgggc acctggcacg agatcgcgcg ctatccgaac tggttccaga agaagtgcgc
      781 gggggattcg cgcgccgact acagcctgct cgagagcggc gaggtgcgcg tggtgaaccg
      841 ctgccgcgag gccgacggca aggtcgcgga ggcggtgggc ttggcgcggc agctcggtgc
      901 ggcggactcg ccgcggctgg aggtgcgctt cgcgccggcc tggctgtcct tcctgcccat
      961 ggtgtggggc gactactggg tgctcgacct cgaccccgac tatcgcttgg tggcggtcgg
     1021 cgagccgagc cgcgagtacc tgtggatcct gtcgcgcacg ccgacggtcg atgcgcgtgc
     1081 ctactccgaa ctgctcgagc gcctcgcggc gcgtggcttc gacgtcggcc ggctggtgcg
     1141 cggggagcag ggcggcggct gaggcggtcg caagggcgga aggcgtagca gttcctgcag
     1201 gtttcgatgc ggtgatggag tccccaagct gggccttttc ggtggtcagg cgagggagct
     1261 gtcagtagaa tcgatttatc gattgattcg aatatgttgc tcatgtatcc gaggcagatc
     1321 ccgtgcgggc ccgctgctag cgctcgctca agccgaagat ggacaggggc ggcctgccgc
     1381 ctgcggtcgc gctcggaggg gggcggcgca taggtgcgcg cgcgatccgc agcgtgctgc
     1441 gtcgtcccgg tctgcgtgag cgcctcgcgc tggcgatggg ggcgttcgtg gtctccatcg
     1501 gcgtcgggct gacgctgctc atggagtggc ggctcgcggc aggtctgcgg gagtccgcgc
     1561 agcagcgcct ggagtatctg gcacgggatc tttcgagtcg catcggtgag gatctgcgtg
     1621 agcgccgcct tgaagtgtcg aggctcgccc tggtcctggg gtcgagcgac gtgctgaact
     1681 cgcgggccgt gcagcagacc ctcgatggct tgcagacgag ggtcccggcg tatgcctgga
     1741 tcggcctcac cgacgcgcgc gggcatgtgc tcgcgggcag cggggggctc ctgagcgggg
     1801 tggatgcatc gacccggccc tggttcctcg gcggcgcccg cgcggagttt ttcggcgacc
     1861 cgcacgtcgc caagatgctc ggcccgctcc tgccccccga gcgcagtggc gagccgttgc
     1921 gtttcttcga cctcgcctcg ccggtgcgcc ggcccgacgg caccatggtg ggcgtgctgg
     1981 gcgcgcacct ctataccggc tggatccgca ccgtggtcga gcgcacgctc gacagccgta
     2041 tcgagcactt tccgctcgag gtcctcgtcg ccgacaacac gggcgactgg ctctacaaga
     2101 cctctcccga cctgagcgcc acgctcgccg ccttgctgcg ggagagtccg ccgacgcgct
     2161 atctgctttc gagcgcgaag gtcgatctcc ccaccgaggc cgggaagctc gcgtggaccg
     2221 tgctggtgcg cgaggaggcg agcgatgcgc tcgcgccggt atatgagaac cgtcggcaga
     2281 tgggcatcgt ggtgcccttg ctcgcgctct cgctcgcctt cgccacctgg ctgatcgcag
     2341 ggcgcctggc gcgcccggtg gagcgcgtgg ccgatgcggc gcggcggcac gccgccacta
     2401 cggggcatgc gctcgacgcc cacgtcgccg gtggccgcga cgaggcgcgc ctgctcgacc
     2461 tcaccctgca gcgcctggcc ctccgcgatt cgctgaccgg gctgatcaac cgcagcgcgc
     2521 tcaagcaacg cctcgcgctc ctgcagcggg cccaggccgt cacggcgtcg cctgcgccct
     2581 acgccgtgct gctgctcgac ctcgacgact tccatatgtt caacaacgct cgcggccacg
     2641 aacacggcga ccagctgctg cgcgccgtcg ccgagcggct gcgccaggtg gcgtgcgccg
     2701 acactgtggc gcgcctgggc agcgacgagt tcgccctgct gcccggcctc ccgggcggcg
     2761 ccgacgagga tgtcgcggcc cacgcgcagg cctacgccga gcgcgtcgtc gcggccttcg
     2821 ccgcgccctt cgagctgccg ggtggcgcgc atcgctgcca ggtctcgatc ggcatcgccg
     2881 tcgtcgacgc cgccgccacg ctcccggagg tggcgctcac cgaggcagag ctggcgatgc
     2941 aggaggccaa gcgcctgggc aaggggcgcg tggtggtctt cgacgaccgg ctgcaggagg
     3001 gcctgatcgc ccagacccgc ttcgagcagg cgctgcgcgc ggcgatcccc tcgcagctgc
     3061 tggtgctcta tcagccgcag gtggatcgcg agggtcgcac ggtcggcgcc gagttgctgg
     3121 tgcgctggaa gcacactgag caaggcctgg tgtcgccggc gatgttcatc ccggtggcgg
     3181 agcagaccgg cctcatcgtg gacatcgggc gctgggtgct ggagcaggcc tgtcgccagc
     3241 tccgcgcctg gagcgacgac cccttgcgcc ggcacctggt gctggcggtg aacgtgagct
     3301 cgcgcgagtt cggtcatcct ggcttcgtag acggggtgcg cgaggtcctc gccgcgaccg
     3361 gcgccgatcc ggcgcgtctc aagatcgagc tcaccgagag cgcgctggcg gccgacgtcg
     3421 gcgaggtggt cgcccgcatg gctgcgctga agagcctggg cgtccgcttc tcgctggacg
     3481 acttcggtac cggcttctcc tcgctcggct acctgcagcg cctgccgctc gaccagctca
     3541 agatcgacca gtccttcgtg cgcggcatgc tcaccgagaa cagcagcgcc tccatcgtgc
     3601 acaccgtgat cgcgctcggc gagagcctcg gggtggaggt gatcgccgag ggggtggaga
     3661 ccgaggcgca gcggcaggcg ctcgcggagc tgggctgcca ccactaccag ggctacctgt
     3721 tcgccagacc ggtcccggtc gagcaactcc cgctatgagc gggtctttcc ttccgtaaag
     3781 gcgaccgggg gctcctcggt gcgctcctcg tcgcggcgca cggtcggcga caagacgggc
     3841 ggcgcgcagg agcgggcgcg ccgcctcgat gaggttccgg gtgacccggg aaccggagaa
     3901 taggtgcggc aatcaccgca ttctgcgcgg tgattttctt gtaattgcgg ggaggaatga
     3961 ccataagcgc cgcatgaatc acggcgatca tctttacatc tggcagtcct ccgcttggcc
     4021 acagtggcgt tatgacctcg ctgcgctggc gcgcccgctt gc
//
LOCUS       DAOTIN010000199         3935 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_27272_length_3935_cov_6.923196, whole genome shotgun sequence.
ACCESSION   DAOTIN010000199 DAOTIN010000000
VERSION     DAOTIN010000199.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 3935)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3935)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3935
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_27272_length_3935_cov_6.923196"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..>1058)
                     /locus_tag="P5537_16505"
     CDS             complement(<1..>1058)
                     /locus_tag="P5537_16505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0009166 - nucleotide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HRV79690.1"
                     /translation="VDVIVGGDSHSLLGDDSLKTFGLAPVGAYPTAARNKDGDTVCVV
                     QAWQYSAVVGELEVLFDGNGTVKSCSGQPHILIGDRLGTLQGDALAAARADLATQPAL
                     RVTAPDTAAGTVLADYAEQVKAFGAEPVAVAQQNLCLRRVPGTKRDASRSKLDGCNQD
                     AHVIAHGGDVQQLVAEAFLLQGQRFGGADISLQNGGGVRVDLATGPVTVGHIYTVLPF
                     KNTLVALTLTGAELRATLEDAMQSVVAGNTGSYPYAGALRWQVDLRQPRGQRIGALEH
                     RNATGQWVAVDEAATYRVITNDFIAAGQDGYTTLGTLDADRREETFLAYADAFLQYAR
                     ETPTLTRPATADFSTQVFA"
     assembly_gap    1059..1158
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<1159..1640)
                     /locus_tag="P5537_16510"
     CDS             complement(<1159..1640)
                     /locus_tag="P5537_16510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HRV79691.1"
                     /translation="MRHPKLPGLLLLAGAIALTGCTDSSSDDAPKPDYRLAILHINDH
                     HSNLDESDASLRLRTGSDDTRTSVPIKLGGFPRVATAMAELSARHDNVLKLHAGDAIT
                     GTLYYTLSEGEADAALMNRVCFDALAVGNHELDSADAGLKTFIDHLWSAPDCRTPVLS
                     A"
     gene            complement(2003..2314)
                     /locus_tag="P5537_16515"
     CDS             complement(2003..2314)
                     /locus_tag="P5537_16515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS histone family protein"
                     /protein_id="HRV79692.1"
                     /translation="MTTYAELQQKIAELQSQAEELRKRELAEIIADVKQKIAAYGLSA
                     ADLGLQAGRESAAPQKTKTALKAKYRDPATGETWVGRGATPKWMRAYLEAGRNKDEFL
                     I"
     assembly_gap    2554..2653
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<2654..2988)
                     /locus_tag="P5537_16520"
     CDS             complement(<2654..2988)
                     /locus_tag="P5537_16520"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004315155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HRV79693.1"
                     /translation="MFDKILTLCTGNICRSPLAEYLLRDRLAARGRAATVASAGIGAL
                     VGHPADETTQRVAQRHGIDLSPHVARQLTPEITRWADLILVMEKHHLEYATRLDPSAR
                     GKIFLLGHW"
     gene            complement(3134..3910)
                     /locus_tag="P5537_16525"
     CDS             complement(3134..3910)
                     /locus_tag="P5537_16525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VPLPA-CTERM sorting domain-containing protein"
                     /protein_id="HRV79694.1"
                     /translation="MKKFALIAATASLAVVSTGASAGYVSTIPSLSGVVEASDFGPDS
                     GGAFDGVFKLRLRDLAGSGTLVVPPNGTYGAEAKGSVAIDTSTTGTFVPEFAFTQATY
                     AAVGTGSFTATGLTAGSYSATFAPGTPGTLDGAGIPIGFSITYNGMLSMPLLGLINMA
                     LGITPPFVDPSGAGKVTVSGTLHSDGVDLVIKEEDLTWAGMEKLLYAADVKLGGAPYG
                     ISDGRFMMRDVSIHVPEPASLALLGLGLVGLGAMRRRKQA"
BASE COUNT          558 a         1037 c         1490 g          650 t
ORIGIN      
        1 gcgaatacct gcgtgctgaa atccgcggtg gcggggcggg tgagggtggg ggtttcgcgg
       61 gcgtattgca ggaaggcgtc ggcgtaggcg aggaaggtct cttcgcggcg gtccgcgtcg
      121 agggtgccga gggtggtgta gccgtcctgg ccggcggcga tgaagtcgtt ggtgatgacg
      181 cggtaggtcg ccgcttcgtc gactgccacc cactggcccg ttgcgttgcg gtgctcgagc
      241 gcgccgatgc gctggccgcg cggctggcgc aggtcgacct gccagcgcag cgcgccggcg
      301 taggggtagg agccggtgtt gccggcgacc acgctctgca tcgcgtcctc gagcgtggcg
      361 cgcagctccg ccccggtgag cgtgagcgcg accagcgtgt tcttgaacgg cagcacggtg
      421 tagatgtggc cgacggtgac ggggcccgtg gcgaggtcga cgcgcacgcc gccgccgttc
      481 tgcagcgaga tgtccgcgcc gccgaagcgc tggccctgga ggaggaaggc ttcggcgacg
      541 agctgctgga cgtcgccgcc gtgggcgatc acgtgtgcat cctggttgca gccgtcgagc
      601 ttcgagcgcg aggcgtcgcg cttggtgccg gggacgcggc gcaggcagag gttctgctgc
      661 gcgacggcga ccggctcggc gccgaaggcc ttcacctgct cggcgtaatc ggcgagcacg
      721 gtgccggcgg cggtgtcggg tgcagtgacg cgcagggccg gctgggtggc gagatcggcg
      781 cgggctgcgg cgagggcgtc gccctggagc gtgccgaggc ggtcgccgat gaggatgtgc
      841 ggctggccgg agcaggactt gaccgtgcca ttgccgtcga agagcacctc gagctcgccg
      901 accacggcgc tgtattgcca ggcctggacg acgcagacgg tgtcgccgtc cttgttccgc
      961 gctgcggtgg ggtaggcgcc gacgggcgcg aggccgaagg tcttgaggct gtcgtcgccg
     1021 agcaggctgt gcgagtcgcc gccgacgatg acgtcgacnn nnnnnnnnnn nnnnnnnnnn
     1081 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1141 nnnnnnnnnn nnnnnnnngc cgagagcacc ggggtgcggc agtcgggcgc ggaccagagg
     1201 tggtcgatga aggtcttcag gccggcgtcg gccgagtcga gctcgtggtt gccgacggcc
     1261 agggcgtcga agcagacgcg gttcatcagc gcggcatcgg cctcgccttc gctgagggtg
     1321 tagtagagcg tgccggtgat ggcgtcgccg gcgtgcagct tgagcacgtt gtcgtggcgc
     1381 gcggagagct cggccatggc ggtggcgacg cgtgggaagc cgccgagctt gatgggcacg
     1441 ctggtgcggg tgtcgtcgct gccggtgcgc aggcgcaggc tggcgtcgga ttcgtcgagg
     1501 ttggagtggt ggtcgttgat gtgaaggatg gccaggcggt agtcgggctt gggcgcgtcg
     1561 tccgatgagg agtcggtgca gccggtgagc gcgatcgcgc cggcgaggag gagcagcccg
     1621 gggagcttgg ggtgacgcat ggcggagcct cgtgtccgtt tcggagatgg acggaggatc
     1681 gcggcgggag gttaagcggt gatgaaagtc gcggggtggt tttggtggag gcgtatgggt
     1741 tggaatgcag gagcgacgca agtcgcgaat agggcgtttg gaattggcgt catcgccgct
     1801 tcaccgctgc attcgcgcct ggcggcgctc ctgcatgggg gatgcggatg gcgtttcgct
     1861 tggtccaggt gctggaggaa ttgcgatgcg attcggccgt cggaaaagaa aaaccccgtc
     1921 cggattacgc tgctttcgcc gcgtcatgat cggatcgggg ttttatgccg gggttttgcc
     1981 ccggtgcgtt accgcaaacg gcttagatca ggaattcgtc cttgttgcgg ccggcttcga
     2041 ggtaggcgcg catccacttg ggcgtggcgc cgcggccgac ccaggtctcg ccggtggcgg
     2101 ggtcgcggta cttggccttg agcgcggtct tggtcttttg cggcgcagcc gattcgcgcc
     2161 cggcctgcag gccgagatcg gcggcgctga ggccataggc ggcgatcttc tgcttgacgt
     2221 cggcgatgat ttcggcgagt tcgcgcttgc gcagttcttc ggcctgggat tggagttcgg
     2281 cgatcttttg ctgcagttcg gcgtaggtgg tcatggctgt tatgtattgt gatggatgag
     2341 aacgggatcg attgtacgcc gatgaaaaac gtttttgaaa gggggactcg aaaaattccg
     2401 gattaaatgg ccgatgattt aattcgaacg gtttgtggtg cccagccgaa tgagcgtatt
     2461 aggaacaacg gataacacgc gccatattaa ccgtcgcggc tcggcgcaat gtaggagcgg
     2521 cggcagccgc gattgggccg acgcgcaatc gacnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2641 nnnnnnnnnn nnntcccaat ggccgagcag gaagatcttg ccgcgcgcgc tggggtcgag
     2701 gcgggtggcg tattcgaggt ggtgcttttc catcaccagg atgaggtcgg cccagcgcgt
     2761 gatctctggg gtgagctggc gcgcgacgtg cggcgagagg tcgatgccgt ggcgctgggc
     2821 gacgcgctgg gtggtctcgt ccgcgggatg gccgacgagc gcgccgatgc cggccgaggc
     2881 caccgtggcc gcgcggccgc gcgcggcgag gcggtcgcgc agcaggtatt cggcgagcgg
     2941 gctgcggcag atgtttccgg tgcaaagggt gaggatcttg tcgaacatgg cggtgtgcga
     3001 gggcgtcggg atcgggcggg gcgtggggcg ccggcgggga tgggtcggcg accgtctcgg
     3061 cccgggagtg taaacgcaaa aaccggcacc ccctcgcgag gatgccggct tgcggtgacg
     3121 cagaagccga ggatcaggcc tgcttgcggc gacgcatcgc gcccagaccg accaggccga
     3181 ggcccagcag ggcgagggag gcgggttcgg ggacgtggat cgaaacgtcg cgcatcatga
     3241 agcggccgtc cgaaatgccg tagggggcgc cgccaagctt gacgtcagcc gcgtacagca
     3301 gcttttccat gcctgcccag gtgaggtcct cttccttgat gacgagatcg acaccatcgc
     3361 tgtgcagcgt gccgctgacg gtgaccttgc cggcgccgct cggatcgacg aacggcgggg
     3421 tgatgccaag cgccatgttg atcaggccga gcagcggcat cgacagcatg ccgttgtagg
     3481 tgatcgagaa gccgatgggg atgccggcac cgtcgagcgt gccgggggtg ccgggggcga
     3541 aggtggccga gtagctgccc gcggtcagac cggtggcggt gaaagagccg gtgccgaccg
     3601 cggcgtaggt cgcttgggtg aaggcgaact caggcacgaa agtgccggtg gtgctggtgt
     3661 cgatcgccac cgagcctttc gcctcggcgc cgtaggtgcc gttcggcggg acgaccagcg
     3721 tgccgctgcc cgcgaggtcg cgcaggcgca gcttgaagac gccatcgaac gcgccgccgc
     3781 tgtcagggcc gaaatccgag gcttcgacga cgccggagag gctcgggatg gtgctgacat
     3841 aaccagccga ggcaccggtg gaaacaacgg caagcgacgc ggtcgctgcg atcagggcaa
     3901 atttcttcat tggcgcaatc ctttaaaact gggac
//
LOCUS       DAOTIN010000200         3926 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_27349_length_3926_cov_6.860243, whole genome shotgun sequence.
ACCESSION   DAOTIN010000200 DAOTIN010000000
VERSION     DAOTIN010000200.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 3926)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3926)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3926
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_27349_length_3926_cov_6.860243"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..599)
                     /locus_tag="P5537_16530"
     CDS             complement(<1..599)
                     /locus_tag="P5537_16530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3047 domain-containing protein"
                     /protein_id="HRV79695.1"
                     /translation="MAAYRCVRRAIALSLMSTATMGQAATEWVGRFPAGAAGLPEPWR
                     VQQLDERIAPTRYALKTWDGVVAVEAVAERSMALLGRPLDIDLEATPHLCWLWRVDAP
                     LATADMRTKAGDDYAARVYLSFRIAPEALGLGTRAKLALARSIYGDQVPDAALNYVWD
                     NRQPVGTSMPNAYTDRTRMIVLRSGTGDAGGWVIERRDVA"
     gene            complement(554..1363)
                     /locus_tag="P5537_16535"
     CDS             complement(554..1363)
                     /locus_tag="P5537_16535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HRV79696.1"
                     /translation="MRCTLAGRTVLDIERLVVGEGERIALVGHNGAGKSTLLRVLSGF
                     TRPTAGQVSVLGARLDTPLPPARLRALRCEAGQVLQGLHLVPRLSALENVLIGSLGRV
                     TGWRSWVRRYPAHECERAHAALAQVGMQGKASMRTDGLSGGERQKVAIARLLVQAPRL
                     ILADEPTAALDPAAAQEICRVLGAATAGATLVSVVHNTALLPLLAERVIGLRQGRIVF
                     DLPRSQLDAAQLAALYGGPSIPVRQRVDEHFKRRQHRWLHTDASAGRSPCR"
     gene            complement(1387..2280)
                     /gene="phnE"
                     /locus_tag="P5537_16540"
     CDS             complement(1387..2280)
                     /gene="phnE"
                     /locus_tag="P5537_16540"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015416 - ABC-type phosphonate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015716 - organic phosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HRV79697.1"
                     /translation="MNLAAPGLRVRPLLRGRAGFLALVLVYALLVAACLGTLAREGEL
                     SLGRSPIANLMKTAGEFARPSVLDVWFGNPKLEYRSDDGTLLRVENRQAVERAWLEGL
                     GRATWTTIRIATLGSLLGALLALPLAVLTARNLAAPRPLAWGAKAVLDTSRSIHTLVF
                     GLVLVGIVGLGPTAGILAIGLHSMGTYGKLFAEAIESLDMAAIEAVRSVGAGPAQVFF
                     NAVWPTVLPQFVSSHLYIWEFNIRDSTILGLIGAGGLGLLITEATALFQWGRLATVLI
                     VIVVMVSGFDAISRRIRQALA"
     gene            complement(2277..3155)
                     /locus_tag="P5537_16545"
     CDS             complement(2277..3155)
                     /locus_tag="P5537_16545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate/phosphite/phosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HRV79698.1"
                     /translation="MPRLVDLLILAITSLAVPAAVAAAPAAEPLRLGVGLFQPDKDKN
                     DATYRPLADYLARALERPVQLRTVDSWEGLAKSLANGETDIALMGPWGYVLANHHAGA
                     QAVATILYDGKPEYFAIMVTHPASGIESIADLEGRTFAFGDKGSTSGYLIPLHHLMTL
                     GITPESYFGKVLHTAHQAIETQVTQRVLDAGADYNRNRNAMIAQGLIRAEDSKIFWTS
                     APLPNDAVALRKELADDADFVARLRAALVGVGPALAQQPALLPPHYTGFVESDNGFYK
                     PIRDAGLATGKLQARP"
     gene            3495..3788
                     /locus_tag="P5537_16550"
     CDS             3495..3788
                     /locus_tag="P5537_16550"
                     /inference="COORDINATES: protein motif:HMM:NF024949.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HRV79699.1"
                     /translation="MARRVVPTPFPTDPQLTTPDALGAAIRAARTASGLTLEEAALAV
                     SIAKQTLGDLEAGKPSVGLGIALRVAKALGVSLFIAPAGEAGAIVQRIREARE"
BASE COUNT          628 a         1430 c         1307 g          561 t
ORIGIN      
        1 gccacatcgc gccgctcgat cacccagccc cccgcatcac ccgtacccga gcgcagcacg
       61 atcatgcgcg tgcggtcggt gtaggcattg ggcatggagg tacccaccgg ctggcggttg
      121 tcccacacat agttgagcgc ggcgtccggc acctggtcac cgtagatcga gcgcgccagc
      181 gccagcttgg cgcgagtgcc gagaccgagc gcctcgggcg cgatcctgaa gctcagatac
      241 acccgtgctg catagtcgtc gccggccttg gtcctcatgt cggccgtggc cagcggtgca
      301 tcgacgcgcc acagccagca caggtgcggc gtcgcctcga ggtcgatgtc gagcgggcgg
      361 ccgagcaagg ccatgctgcg ctcggccacc gcctcgaccg cgacgacgcc atcccaggtc
      421 ttgagcgcgt accgcgtcgg cgcgatgcgc tcgtcgagtt gctggacgcg ccagggttcg
      481 ggcaggcccg cagcaccggc aggaaaccgt cccacccact ccgtggcggc ctgccccatg
      541 gtggcggtgg acatcagcga cagggcgatc gcccggcgga cgcatcggta tgcagccatc
      601 tgtgttgtct ccgtttgaag tgctcatcca cgcgctggcg caccggaatc gatggaccgc
      661 catacagcgc ggccagttgc gccgcatcga gctgcgaccg gggcagatcg aacacgatcc
      721 gcccctgccg caagccgatc acccgctccg ccagcagcgg cagcagcgcc gtgttgtgca
      781 ccaccgacac cagcgttgcg ccagcggtgg cggcgccgag cacccggcag atctcctgcg
      841 ccgctgcggg gtcgagcgcc gccgtcggct cgtcggccag gatcagccgc ggcgcctgca
      901 ccagcaggcg ggcaatcgcc accttctgcc gctcgccgcc ggagagcccg tcggtgcgca
      961 tcgacgcctt gccctgcatg ccgacctgcg ccaacgcagc atgtgcccgt tcgcattcgt
     1021 gcgcggggta acgccgcacc cagctgcgcc agcccgtcac gcgcccgagg ctgccgatga
     1081 gcacgttctc gagcgcgctc agtcgcggca ccagatgcag cccctgcagc acctgcccgg
     1141 cctcgcaacg cagcgctcgc agccgggcgg gtggcagcgg cgtatccagc cgcgcgccca
     1201 gcaccgacac ctgccccgcc gtcggccgcg tgaagccgct cagcacgcgc agcagggtcg
     1261 acttgcccgc gccgttgtga ccgacgaggg cgatgcgctc gccctcgccc accaccagcc
     1321 gctcgatgtc cagcaccgtg cggccggcga gcgtgcagcg caccccgcgc aggtcgatgc
     1381 aggcgctcat gcgagcgcct gccggatgcg gcggctgatg gcgtcgaagc cggacaccat
     1441 caccacgatc acgatcagca ccgtcgccag ccgcccccac tggaacagcg ccgtcgcctc
     1501 ggtgatcagc aagcccagcc cgcccgcgcc gatgagccca aggatggtcg agtcacggat
     1561 gttgaactcc cagatgtaca ggtggctgga gacgaactgc ggcagcacgg tcggccacac
     1621 cgcgttgaag aagacctgcg ccggccccgc gcccacgctg cgcaccgcct cgatcgccgc
     1681 catgtcgagc gactcgatgg cctcggcgaa gagcttgccg taggtaccca tcgagtgcag
     1741 cccgatcgcc aggatgccgg cggtcggccc caggccgacg atgccgacca gcaccaggcc
     1801 gaacaccagg gtgtggatcg agcggctggt gtcgagcacc gccttcgcgc cccaggccag
     1861 cggccgcggc gccgccaggt tgcgcgcggt gagcaccgcc agcggcagcg ccagcagcgc
     1921 gcccagcaac gagccgagcg tggcgatgcg gatcgtggtc caggtggccc gccccaggcc
     1981 ctcgagccac gcacgctcca ccgcctggcg gttctccacc cgcagcaggg tgccgtcgtc
     2041 gctgcggtac tcgagcttcg ggttgccgaa ccacacatcg agcacgctcg ggcgcgcgaa
     2101 ctcgccggcg gtcttcatca ggttggcgat cggcgatcgc cccagcgaca gctcgccctc
     2161 gcgcgccagc gtgcccaggc aggcggcgac cagcagcgca tacaccagca ccagcgccag
     2221 aaagcccgca cgcccgcgca acagcggacg cacgcgcagg cccggggcgg ccaggttcat
     2281 ggccgcgcct gcagcttgcc ggtcgcgagc ccagcgtcgc gaatcggctt gtagaagccg
     2341 ttgtcgctct cgacgaagcc ggtgtagtgc ggcggcagca gcgccggctg ttgcgccagc
     2401 gccggcccca cgcccaccag cgccgcgcgt agccgggcga cgaagtcggc gtcgtccgcg
     2461 agctccttgc gcagcgccac cgcgtcgttg ggcaagggcg ccgaggtcca gaagatcttc
     2521 gagtcttccg cccggatcag cccctgcgcg atcatcgcgt tgcggttgcg gttgtagtcc
     2581 gcgccggcat cgagcacgcg ctgcgtcacc tgggtctcga tcgcctggtg cgcggtgtgc
     2641 agcaccttgc cgaagtagga ctccggcgtg atgcccagcg tcatcaggtg gtgcagcggg
     2701 atcaggtagc ccgaggtcga gcccttgtcg ccaaaggcga aggtccgccc ctcgaggtcg
     2761 gcgatcgact cgatcccgga agcggggtgc gtcaccatga tcgcgaagta ttccggcttg
     2821 ccgtcgtaca ggatggtcgc caccgcctgc gcaccggcgt ggtggttggc caggacatag
     2881 ccccacggcc ccatcagcgc gatgtcggtc tcgccattgg ccagcgactt ggccagcccc
     2941 tcccagctgt cgacggtgcg caactgcacc gggcgctcga gcgcgcgcgc aaggtagtcg
     3001 gccagcggcc ggtaggtggc gtcgttcttg tccttgtcgg gctggaacag tcccacgccc
     3061 aggcgcagcg gctcggccgc gggcgcagcc gcaaccgcgg ccggcacggc gaggctggtg
     3121 attgcaagaa tgagaaggtc gacaaggcgc ggcatggggg gctctccggg gctatgtgct
     3181 gtaagacatg cagaccgccg accatccggc gcgtcttgaa gcttggtcgg aggagcaagg
     3241 catttcttac agcaggggag agagcacgct gccccgtttt tgcgccaagc ccccaaaagc
     3301 tccccaggag cgtgggcatc ccacacgcac agcacgtgct ccgccaccta gcgcaatccg
     3361 ctgctttaca cctgccaacc taggcgtaat caacccgatg acctaccgca ccacctattc
     3421 gcctacctgg ataggatctt cttcgagcaa tgcgcctgaa tcgcctatac tcctaccatc
     3481 ctgggagtat tttcatggcg cgtcgtgttg tccctacccc gttccctacc gatccgcagc
     3541 tcacaacgcc tgacgcactc ggggcggcca ttcgtgcggc tcgcaccgcc agcgggctga
     3601 cgctcgaaga agcggcgctg gcggtgagta tcgccaaaca gaccctgggc gacctggagg
     3661 caggcaagcc aagcgtcggg ctggggatcg ccctgcgggt ggcgaaggcg cttggcgtga
     3721 gcctcttcat cgcgccagcg ggtgaggccg gcgcaatcgt gcagcgcatc cgcgaggcgc
     3781 gtgaatgatg aagctcgacg tgctgatgaa tggcgagctg gcgggcacgc tgagctacac
     3841 ggcgcagacg caccgctatg cgttcgacta cagcccggcg tggctgtcac gcaaggtgcg
     3901 ctacgccctc ggcccgacct tgccgc
//
LOCUS       DAOTIN010000201         3915 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_27444_length_3915_cov_9.019430, whole genome shotgun sequence.
ACCESSION   DAOTIN010000201 DAOTIN010000000
VERSION     DAOTIN010000201.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 3915)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3915)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3915
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_27444_length_3915_cov_9.019430"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            409..1578
                     /locus_tag="P5537_16555"
     CDS             409..1578
                     /locus_tag="P5537_16555"
                     /EC_number="1.14.19.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004373022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid desaturase"
                     /protein_id="HRV79700.1"
                     /translation="MYNGLFDLPWWGYVLVALALTHVTIVSVTVFLHRHQAHRALELH
                     ALPSHFFRFWLWLTTGMVTKEWAAIHRKHHAKCETAEDPHSPQTRGLRKVLWEGAELY
                     RAEAKNAETLQRFGHGTPDDWLERNVYRHSVVGVAIMLVIDLVAFGPLGLTIWAVQMA
                     WIPFWAAGVVNGVGHFWGYRNYDCDDASRNLLPWGLLIGGEELHNNHHSFATSAKLSA
                     KWYEFDVGWMYIRMLELLGLAKVKKTIPRPRFGEAKPVPDLDTLQAIVTHRYDVMTRY
                     VRSLRAVFADEARRLREAHGLALSARRLRRWVLGGELRGLDEVQRRQLEQAVEASPAL
                     RTVAAMRDELAALWSRSNASREQLLAQLQDWVARAERSGIRQLEEFSLRLRSYAC"
     gene            complement(1608..2051)
                     /gene="queD"
                     /locus_tag="P5537_16560"
     CDS             complement(1608..2051)
                     /gene="queD"
                     /locus_tag="P5537_16560"
                     /EC_number="4.1.2.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004316710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-carboxytetrahydropterin synthase QueD"
                     /protein_id="HRV79701.1"
                     /translation="MRITRRLEFDAGHRIPDHASQCRHLHGHRYALEVTLSGDIIKAD
                     GVPVNGMVMDFADVKRIANEYVVGPWDHAFLAYRGDNLVLDMLAAIPGHKTVVLDVVP
                     TAENLAAEAFRILDPAYRDTYGNHLRLERVRLYETPNCWADALRD"
     gene            2139..3017
                     /locus_tag="P5537_16565"
     CDS             2139..3017
                     /locus_tag="P5537_16565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004316707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HRV79702.1"
                     /translation="MNSSHEMPPGTVATLKVSNHDRDLAGLTYVYPVLSRRAGGVSIG
                     INLNPNNACNWHCAYCQVPGLVRGKAPAIDLPRLEAELRGFLADLIHGDWMTRHVPEG
                     ARVIRDIAFSGNGEATSAEVFPEAVALVLRLRDEFGLSSQAVPVRLITNGSLLAQGHV
                     QEGVRRLGEAGGEVWFKVDGGSVEAIERINGVRLEPAAVARNLARCAELCPTWVQTCM
                     FRWDGALPTDTDIDAWLAVLEAAGTERLRGVLLYGVARPSMQAEAPRISTLTVDELEA
                     IAERARKKGLTVRVSP"
     gene            complement(3035..3328)
                     /locus_tag="P5537_16570"
     CDS             complement(3035..3328)
                     /locus_tag="P5537_16570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HRV79703.1"
                     /translation="MKANEKLDVREIRRKLGLNQSQFWSKIGVTQSGGSRYESGRNIP
                     RPVQALLRLVHVEQIDINKVKRDDVEVAEYLKTTNPELYKTLKKEARAKRKER"
     gene            3690..3830
                     /locus_tag="P5537_16575"
     CDS             3690..3830
                     /locus_tag="P5537_16575"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79704.1"
                     /translation="MAVLAAVIGGERGGLSAPAGEVVRRRIGAFDQRLTGSHELAMIA
                     PS"
     gene            3840..3915
                     /locus_tag="P5537_16580"
     tRNA            3840..3915
                     /locus_tag="P5537_16580"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3866..3868,aa:Ser,seq:gct)
BASE COUNT          609 a         1215 c         1377 g          714 t
ORIGIN      
        1 ggcgcgggcg tcgcgatgct tcatgtagga gggccggcag gcgcgaaagc ggcggcgcgg
       61 caagcggcca cgtcgccatc ccgcaggccc cgttcgcggc tgccgccgct cctacacgag
      121 gcgcgggcgc gtcgcgacgg ttcatgtagg agcgccggca ggcgcgaaag cggcggagcg
      181 gcatgcggcc acgtcgccct tgcgcaggcc ccgttcgcgg ctgccgccgc tcctacacaa
      241 ggcgcgggcg tcgcgatgct gcatgtagga gcgccggcag gcgtgaaagc ggtgcctgaa
      301 tgacccttgc cgtgatgggg tgtggtaaca gtttccggac ttgatccaat tcttgtcggg
      361 cctgcgtaga atcgtgtcgc tgttcacttc ttccggacgt ttccgcgcat gtacaacggt
      421 ttgttcgatc tcccgtggtg gggctacgtg ctggtggcgc tcgcgctcac ccacgtcacc
      481 atcgtctccg tcaccgtctt cctgcatcgc caccaagcgc accgcgcgct cgagctgcat
      541 gcgctgccca gccatttctt ccgcttctgg ctgtggctga ccaccggcat ggtgacgaag
      601 gagtgggcgg cgatccaccg caagcaccac gccaaatgcg agaccgcgga ggatccgcac
      661 agcccgcaga cgcgcggcct gcgcaaggtg ttgtgggagg gggcggaact ctaccgcgcc
      721 gaggcgaaga acgccgagac cctgcagcgc ttcggtcacg gtacgcccga cgactggctc
      781 gagcgcaatg tgtatcgcca ctccgtcgtc ggcgtcgcca tcatgctggt gatcgacctc
      841 gtcgccttcg gtccgctcgg cctcacgatc tgggcggtgc agatggcctg gattccgttc
      901 tgggcggcgg gggtggtcaa tggcgtgggg cacttctggg gctaccgcaa ctacgactgc
      961 gacgacgcct cgcgcaacct gctgccctgg ggcctcctga tcggcggcga ggagctgcac
     1021 aacaaccacc acagcttcgc cacctcggcc aagctgtcgg caaagtggta cgagttcgac
     1081 gtcggctgga tgtacatccg catgctcgag ctgctcggct tggccaaggt gaagaagacg
     1141 atcccgcggc cccgattcgg cgaggccaag ccggtacccg acctcgatac cttgcaggcg
     1201 atcgtgaccc accgctacga cgtgatgacg cgctacgtgc gatcgttgcg cgccgtcttc
     1261 gccgacgagg cacggcggct gcgcgaggcg cacgggctgg cgttgagcgc gcgccgcttg
     1321 cggcgctggg tgctgggagg cgagctgcgt gggctggacg aggtgcagcg caggcagctg
     1381 gaacaggcgg tcgaggccag cccggcgctg cgtacggtgg cggcgatgcg tgacgagctc
     1441 gccgcgctgt ggtcgcgttc gaacgcgagc cgcgagcagc tgctcgcgca gttgcaggac
     1501 tgggtggcgc gcgccgagcg cagcggcatc cgccagctgg aggagttctc gctgcggctg
     1561 cgcagctacg cttgttgagg cgtcaggcgt cgggcgtcag gcgcggctca atcgcgcagg
     1621 gcgtcggccc agcagttggg ggtctcgtag aggcgcacgc gctcgagcct gaggtggttg
     1681 ccgtaggtgt cgcgataggc cggatcgaga atgcgaaagg cctcggcggc gaggttctcg
     1741 gcggtgggca cgacgtcgag caccacggtc ttgtggccgg ggatcgcggc cagcatgtcg
     1801 agcaccagat tgtcgccccg gtacgcgagg aaggcgtggt cccagggacc cacgacgtat
     1861 tcgttggcga tgcgcttgac gtcggcgaag tccatcacca tgccgttgac cggcacaccg
     1921 tcggccttga tgatgtcgcc cgacagcgtc acctccagcg cgtagcggtg gccgtgcaga
     1981 tgccggcatt ggctggcgtg gtccggaatc cggtgtccgg cgtcgaattc gaggcggcgg
     2041 gtgatgcgca tggcgagtct ctctggaacg gccccggagt atagcaccgg ggagtccgcg
     2101 ccgatcccgc gtattttccg caagtatctg aacgaacgat gaattcttcc cacgaaatgc
     2161 cgcccggcac ggtcgcgacg ctgaaggtga gcaaccacga tcgcgacctc gccgggctga
     2221 cctacgtcta tccggtgctg tcgcgtcgtg ccggtggggt gtcgatcggc atcaacctga
     2281 acccgaacaa cgcctgcaac tggcattgcg cctactgcca ggtgcctggc ctggtgcgtg
     2341 gcaaggcacc ggcgatcgac ctcccacgac tcgaggccga actgcgtggc ttcctcgccg
     2401 acctgatcca cggcgactgg atgacgcgcc acgtgcccga aggcgcgcgc gtgattcgcg
     2461 acattgcctt ctcgggcaat ggcgaggcga ccagcgccga ggtcttccct gaagcggtcg
     2521 cgctcgtgct gcggctgcgc gacgagttcg gcctgtcgtc gcaggccgtg cccgtgcgcc
     2581 tgatcaccaa cggcagcctg ctcgcgcagg gccacgtgca ggaaggcgtg cgccggctgg
     2641 gcgaggcggg cggcgaggtg tggttcaagg tggatggcgg cagcgtcgag gcgatcgagc
     2701 gcatcaacgg cgttcggctc gaacctgcgg cggtggcgcg caatctcgcg cgctgtgcgg
     2761 agctgtgtcc gacctgggtg cagacctgca tgttccgctg ggatggagcg ctgccgacgg
     2821 acacggacat cgacgcctgg ctggctgtgc tggaggccgc cggcaccgag cgcctgcgcg
     2881 gtgtgctgct ctatggcgtg gcgcggccgt cgatgcaggc ggaggcgccg cggatctcga
     2941 cgctgacggt ggacgagctc gaggcgatcg ccgagcgcgc ccgaaaaaaa gggctgacgg
     3001 tacgcgtcag cccttgatcg tgcgcggcat gcgctcagcg ctccttgcgc ttggcgcgtg
     3061 cttccttctt gagggtcttg tagagctcgg ggttggtcgt cttgaggtac tctgcgacct
     3121 cgacgtcgtc acgcttgacc ttgttgatgt cgatctgctc gacgtggacc aggcgcagca
     3181 aggcctgcac cgggcggggg atgttgcggc cgctctcgta gcgggagccg ccgctctggg
     3241 tcacgccgat cttggaccag aactgcgact ggttcaggcc gagcttgcga cgaatttcac
     3301 gtacatccag cttttcgttt gctttcatgg agatttcctc gagtttgcat ggctccgggc
     3361 catcccggat tcgatgcgga caggatcctg cctatgacct tggtcataga acgcatgcag
     3421 tataggttag tatccgggct acatacaaaa tagattttag ctattttggc gaatttcgca
     3481 ggaaattcac gtcttggaga ttttgtttcg atccggcgag caaaacttca cgccctgacc
     3541 agcatcgtga accttattca cttggggtgt tggataggac gatggcacgg atagttcgga
     3601 aggtgggcct tgcctcggtg cgaaaccccg aatgcatccg tcgcgaagcc gcgcgatgga
     3661 ttgcgtgctc ccgtgcacag gaggttcgcg tggccgtcct tgcagcggtg atcggcggtg
     3721 agcgcggggg cctgtcggcg cccgccggcg aggtggtgcg ccgccgcata ggtgcgttcg
     3781 atcaacgttt gaccggcagt cacgaactcg ctatgatcgc gccttcctga tggagacgtg
     3841 gccgagaggt cgaaggcact cccctgctaa gggagcatgc gggctaaaac tcgcatcgag
     3901 ggttcgaatc cctcc
//
LOCUS       DAOTIN010000202         3888 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_27673_length_3888_cov_6.299243, whole genome shotgun sequence.
ACCESSION   DAOTIN010000202 DAOTIN010000000
VERSION     DAOTIN010000202.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 3888)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3888)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3888
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_27673_length_3888_cov_6.299243"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..530)
                     /locus_tag="P5537_16585"
     CDS             complement(<1..530)
                     /locus_tag="P5537_16585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter
                     substrate-binding protein"
                     /protein_id="HRV79705.1"
                     /translation="MFKKMLVRTLATAIVAATAGTAFAADATDWPKRPVQVVVPANAG
                     GDTDFNARTMAKYFTQLTGKSMVITNMAGGGGTIAVSQVQGAKPDGNTILFAHTGQLV
                     VNEVSGLTEDSFDVLDIACIAAVDKGAVFVSSKASGIKDVKDLVDKAKAAPGTVVYGT
                     EMGGFSHLQGLMFEKLA"
     gene            complement(578..1993)
                     /locus_tag="P5537_16590"
     CDS             complement(578..1993)
                     /locus_tag="P5537_16590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enolase C-terminal domain-like protein"
                     /protein_id="HRV79706.1"
                     /translation="MTDTPHTTSPIVTEMQVIPVAGHDGMLLNLCGAHAPWFTRNLVI
                     LRDNAGRTGVGEVPGGEGILRTLERSRALVVGTQVGRYNRTLNTLRQAIAGGGDGMPQ
                     RTVHQVSSEAEARVLKQPHEINLRLDNVLTAVEAALLDLLGQHLGVPVAELLGSGQQR
                     ARTPMLAYLFYIGDRGRTDLPYLSGDEADAPRDHDWYRTRHLEAVTPETIARQAASAA
                     DRYGFRDFKLKGGVMHGSEEMEAVAAIKARFPDARVTLDPNGAWSLAEAIALCKGQGH
                     LLAYAEDPCGPENGFSGREVMAEFRRATGIPTATNMVATDWRQMGHSVRLDAVDIPLA
                     DPHFWTMQGSVRLAQLCEAWGLTWGSHSNNHFDISLAMFTHCAAAAPGRITAIDTHWI
                     WQEGTERLTREPLQIVGGEVAVPDRPGLGIEPDMDRILQAHELYKKVGTGARDDAMAM
                     QYLVPGWKYDPKQPSLGRKRG"
     gene            complement(2037..2801)
                     /locus_tag="P5537_16595"
     CDS             complement(2037..2801)
                     /locus_tag="P5537_16595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004356954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase/citrate lyase family protein"
                     /protein_id="HRV79707.1"
                     /translation="MDLPINRFKHAIQSGQKQIGLWSHLCSNISTEILAHCGYDWLLL
                     DMEHSPNEVGTILSQLQAMNGGSATAIIRPYWNDMVLFKRLLDIGVQTLLVPYVQTEE
                     EARNAVAYTRYPNRGVRGYAGAPRASNYGRIKDYAQRCEDEICVLVQVETVEGLKNIE
                     AIASVEGIDGVFIGPGDLSAALGHLGNPKHPEVLAAIEDAIRRIQACGKAAGILTGDE
                     TLAKRYVELGCLFVAVGADQNVLRDGAQALAQRFKA"
     gene            complement(2901..3785)
                     /gene="glxR"
                     /locus_tag="P5537_16600"
     CDS             complement(2901..3785)
                     /gene="glxR"
                     /locus_tag="P5537_16600"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008679 - 2-hydroxy-3-oxopropionate
                     reductase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046487 - glyoxylate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HRV79708.1"
                     /translation="MKLGFIGLGIMGAPMAGHLLAAGHELFAQSFGGVPAQLQEQGAK
                     VCSNAREVAQQADIVFVMVPDTPHVADVLFGANGAAEGLSAGKTVVDMSSISPIATKD
                     FAQRINALGCEYLDAPVSGGEVGAKAASLTIMVGGSEASFAKVKPLFELMGKNITLVG
                     GNGDGQTCKVANQIIVALNIEAVGEALLFASKAGADPAKVRQALMGGFASSRILEVHG
                     ERMINRTFNPGFRIELHQKDLNLALEGARALGLSLPHTASALQLMNACAAHGGAGWDH
                     SGLVQALEIAANHKIAGN"
BASE COUNT          533 a         1211 c         1468 g          676 t
ORIGIN      
        1 gcgagcttct cgaacatcag gccctgcaga tgcgagaagc cgcccatctc ggtgccatac
       61 accacggtgc cgggcgcggc cttggccttg tcgaccagat ccttgacatc cttgatgccc
      121 gaggccttgc tgctgacgaa taccgcgccc ttatccaccg cagcgatgca ggcgatatcg
      181 agcacgtcga agctgtcctc ggtgaggcct gatacctcgt tcaccacgag ctggccggtg
      241 tgggcgaaca ggatggtatt gccgtcgggt ttggcaccct ggacctggga cacggcgatc
      301 gtgccgccgc cgccggccat gttggtgatg accatcgact tgccggtgag ctgggtgaag
      361 tacttggcca tggtgcgggc attgaagtcg gtgtcgccgc cggcgttggc ggggacgacg
      421 acctgcaccg ggcgcttggg ccagtcggtg gcgtcggcgg cgaaggcggt gccggcggtg
      481 gcggcgacga tcgcggtggc gagggtcctg acgagcatct tcttgaacat ggtgttgatc
      541 tccttccggg ttgtgccgtg gcgaggcggt gtgggaatca gccgcgcttg cggccgagac
      601 tgggttgctt ggggtcgtac ttccagccgg ggacgaggta ctgcatggcc atggcgtcgt
      661 cccgggcgcc ggtgccgacc ttcttgtaga gttcgtgggc ctgcaggatg cggtccatgt
      721 cgggctcgat gcccaggccc gggcgatccg gcacggcgac ctcgccgccg acgatctgca
      781 gcggctcgcg ggtcaggcgc tcggtgcctt cctgccagat ccagtgggtg tcgatggcgg
      841 tgatgcgccc gggcgcggcg gcggcgcaat gggtgaacat cgccagcgag atgtcgaagt
      901 gattgttcga atgcgagccc caggtcaggc cccaggcctc gcacaactgc gccagccgca
      961 ccgagccctg catggtccag aagtgcgggt cggcgagcgg aatgtcgacc gcgtcgaggc
     1021 gcaccgaatg ccccatctgg cgccagtcgg tggcgaccat gttggtggcg gtggggatgc
     1081 cggtggcgcg gcggaactcg gccatcacct cgcggccgga gaagccgttc tccggtccgc
     1141 agggatcttc ggcataggcc aggaggtggc cctggccctt gcacagcgca atcgcctcgg
     1201 ccagcgacca ggcgccgttg gggtcgaggg tgacgcgggc gtcggggaag cgggccttga
     1261 tcgcggccac cgcttccatc tcctcgctgc cgtgcatgac gccgcccttc aacttgaagt
     1321 cgcggaagcc atagcggtcg gcggcggatg cggcctggcg ggcgatggtc tcgggcgtga
     1381 ccgcctcgag gtggcgggtg cggtaccagt cgtggtcgcg cggcgcgtcg gcctcgtcgc
     1441 cggacaggta gggcaggtcg gtgcggccgc ggtcgccgat gtagaacagg taggcgagca
     1501 tcggcgtgcg tgcgcgctgc tggccgctgc cgaggagttc cgcgaccggc acgccgaggt
     1561 gctggccgag caggtcgagc agcgcggcct cgaccgcggt gagcacgttg tccaggcgca
     1621 ggttgatctc gtgcggctgc ttgagcacgc gggcttcggc ttccgagctc acctggtgca
     1681 cggtgcgctg cggcatgccg tcgccaccgc cggcgatcgc ctggcggagg gtgttgagcg
     1741 tgcggttgta gcgccccacc tgggtgccga cgaccagcgc gcggctacgc tcgagcgtgc
     1801 gcaggatgcc ttcgccgccc ggcacctcgc cgacgccggt gcggccggcg ttgtcgcgca
     1861 ggatgacgag attgcgggtg aaccagggcg catgcgcgcc gcacaggttg agcagcatgc
     1921 cgtcgtggcc ggccaccggg atgacctgca tctcggtgac gatcgggctg gtggtgtgcg
     1981 gagtgtcggt catggcggtc ggtttcctcg tccgggtggt cggtggccgc ggccgatcag
     2041 gccttgaagc gctgcgccag cgcctgcgcg ccgtcgcgca gcacgttctg gtcggcgccg
     2101 acggcgacga acaggcagcc gagctcgacg tagcgcttcg ccagcgtctc gtcgccggtg
     2161 aggatgccgg cggccttgcc gcaggcctgg atgcggcgga tggcgtcttc gatcgcggcc
     2221 agcacctcgg ggtgcttggg gttgccgagg tggccgagcg cggccgagag gtcgcccggg
     2281 ccgatgaaga cgccgtcgat gccttccacg ctggcgatgg cctcgatgtt cttcaggccc
     2341 tcgacggtct ccacctgcac cagcacgcag atctcgtcct cgcagcgttg ggcgtagtcc
     2401 ttgatgcggc cgtagttgga ggcgcgcggg gcgccggcgt agccgcgcac gccgcggttc
     2461 gggtagcgcg tgtaggcgac cgcattgcgc gcctcctcct cggtctgcac gtagggcacg
     2521 agcagggtct gcacgccgat gtcgagcagg cgcttgaaca gcaccatgtc gttccagtag
     2581 ggacggatga tcgccgtggc gctgccgccg ttcatcgcct gcagctgcga caggatggtg
     2641 ccgacctcgt tgggcgagtg ctccatgtcg agcagcagcc agtcgtagcc acagtgggcg
     2701 aggatctcgg tgctgatgtt gctgcacagg tgcgaccaca ggccgatctg cttctggccg
     2761 gactggatgg cgtgcttgaa acggttgatg ggcaggtcca tggtcgtttc cgatgcgcta
     2821 ggcaaaaagg tggcgggcac tgcggcgact tgcgtcatcc acggcgcccg ccgtgggaga
     2881 gcggagggat cgggcgcggc tcagttgccg gcgatcttgt ggttggcggc gatctcgagc
     2941 gcctgcacca ggccggagtg gtcccagccg gcgccgccgt gggccgcgca ggcattcatc
     3001 agctgcagcg cgctggcggt gtgcggcagc gacaggccga gcgcgcgcgc gccttcgagg
     3061 gccaagttga ggtccttctg gtgcagctcg atgcggaagc cggggttgaa ggtgcgattg
     3121 atcatgcgct cgccgtgcac ctcgaggatg cgcgaggagg cgaagccgcc catcagcgcc
     3181 tggcgcacct tggcggggtc ggcgccggcc ttggaggcga acagcagcgc ctcgccgacg
     3241 gcctcgatgt tgagcgcgac gatgatctgg ttggccacct tgcaggtctg gccgtcgccg
     3301 ttgccaccga ccagggtgat gttcttgccc atgagttcga acagcggctt gaccttggcg
     3361 aagctggcct cgctgccgcc gaccatgatg gtcaggctgg cggccttggc gccgacctcg
     3421 ccgccggaga ccggggcgtc gaggtactcg cagcccagcg cgttgatgcg ctgggcgaag
     3481 tccttggtgg cgatcggcga gatcgagctc atgtcgacca cggtcttgcc ggcggacagg
     3541 ccttcggccg cgccgttggc gccgaacagc acgtcggcga cgtgcggggt gtcggggacc
     3601 atgacgaaca cgatgtcggc ctgctgcgcg acttcacggg cgttggagca caccttggcg
     3661 ccttgctcct gcagttgcgc gggcacgccg ccaaaggatt gcgcgaacag ttcgtggccg
     3721 gcggcgagca ggtggcccgc catcggtgcg cccatgatgc cgaggccgat gaatccgagt
     3781 ttcatgtgag ttctccgtga tcgttgaagc ggtttcgggg tgaagggcag ggctcagcgc
     3841 accatgcacg ggcgcttgtt gtcgaaggtc cagcccggga tcaggtac
//
LOCUS       DAOTIN010000203         3865 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_27902_length_3865_cov_5.668241, whole genome shotgun sequence.
ACCESSION   DAOTIN010000203 DAOTIN010000000
VERSION     DAOTIN010000203.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 3865)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3865)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3865
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_27902_length_3865_cov_5.668241"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     assembly_gap    182..281
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(482..1534)
                     /locus_tag="P5537_16605"
     CDS             complement(482..1534)
                     /locus_tag="P5537_16605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004360650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YCF48-related protein"
                     /protein_id="HRV79709.1"
                     /translation="MNPLSTLRHLRALLSATCIATCFSPSLSSTLSATVSASLVLAAG
                     AAHAQGAATDPAAFVPRPAVRSPFAERSMILDATRAGTRLVAVGERGVVLLSDDEGAH
                     WRQAGTVPVDATLTAVSFADARQGWAVGHLGVILHSADGGETWSVQRIDSVEDRPLFS
                     VAFTDAHNGVAVGLWSLMLRTRDGGRTWEEAELPPPPGETRADANLMSVFGDAQGRLF
                     IAGERGLVLRSLDAGESWSYHPTGYRGTFWSGTALADGTLIVGGLRGSVYRSTDGADS
                     WQRVETGSQSSVTDFVALDGRVFAVGLDGVSLDSRDGGASFELSRRADRLSLTAAVAT
                     TDGGVVRFSRAGLVRD"
     gene            complement(1548..>3865)
                     /locus_tag="P5537_16610"
     CDS             complement(1548..>3865)
                     /locus_tag="P5537_16610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="MMPL family transporter"
                     /protein_id="HRV79710.1"
                     /translation="RFRGSILVALMLFTGLMGYYALQLRMDAGFEKQMPIGHEYIRTF
                     DKYRDDVLGANRLNIVVKARSGDIWTQAGLERLYEVTQAVSFLPNVDRLGVQSLWTPN
                     SFVNEITEDGFRADPLISGTIMPRDLTPEIIAGIQRAASQGGFIGTLVARDQTSAMIV
                     AELHERDREGKALDYVAYNRILEALRAKFEDAQFEVQIIGFAKQIGDIADGASAVLEF
                     CAIALLLTALAVYWYCHSVRFTLLPIVCSLTSLVWQFGTLKLLGYGLDPLAVLVPFLV
                     FAIGVSHGVQQINFIVRELSHGKSSDEAARASFTGLLIPGTLALVTAFVSFITLILIP
                     IPMVRELAITASLGVGYKIVTNLVMLPLAASLFTFTKEYADKAVLKREKRSAWLRTLA
                     RVAEPRNAAIVIALTLAVFAVAVWQSHDRVIGTVQPGAPELRAEARFNRDAVSIASSY
                     DTGLDWLTVIFEAPPDACDDVAVGRYQDRFVAEMQYVPGVLSALSFSGQLRTYNEGYN
                     EGNPKMSVVPGDPGNYAALATEIGRVRGFMNKDCSMTAVHLFLSDHKATTINRVIDAV
                     KAFRERDREPGLAIRLASGNAGVQAAVNEEVHKSELPMMLYVYAAIMVLVAMMYRDFR
                     AVIACCLPLTVGTFIGYWFMKELEIGLTVATLPVMVLAVGIGVDYAYYIYNRLQLHLA
                     NGENIVKALEHSILEVGTATIFTAITLAAGVATWMFSELKFQADMGKLLAFMFMVNMV
                     MAMTALPAFAVWMERLFPRKGPVRAPGILAH"
BASE COUNT          619 a         1302 c         1303 g          541 t
ORIGIN      
        1 ggcctgagcg aagccgcatt cgcgcctgcc ggcgctccta catgaaccgt cgcggttccg
       61 tcccctgtag gagcggcggc agccgcgaat gggcggtggg atggcgacgg gcgatgtcgc
      121 ggttccacac gccgcattcg cgcctgccgg cgctcctaca tgaaccgtcg cgattccgtc
      181 cnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ncggacgatc tcgcggttcg
      301 acacgccgca ttcgcgcctg ccggcgctcc tacatgaacc gtcgcgattc cgtcccctgt
      361 aggagcggcg gcagccgcga atgggcggtg tgggatgacg acggacgatc tcgcggttcg
      421 acacgccgca ttcgcgcctg ccggcgctcc tacatgcacc gtcgcggggt gcgcggcagg
      481 atcagtcgcg caccaggccg gcgcgtgaaa agcgcaccac gccgccgtca gtggtcgcca
      541 ccgcggcggt cagcgacagg cgatccgccc gccgcgagag ctcgaagctc gcgccaccgt
      601 cgcgactgtc caggctgacg ccgtcgaggc cgacggcgaa caccctgccg tcgagggcga
      661 cgaaatccgt caccgagctc tgcgagccgg tctcgacgcg ctgccagctg tcggcgccgt
      721 cggtgctgcg atagacgctg ccgcgcaggc cgccgacgat cagcgtgccg tcggcgagcg
      781 ccgtgccgct ccagaaggtc ccgcgatacc cggtcgggtg atagctccag ctctcccccg
      841 cgtcgagcga acgcaacacc aggccgcgct cgccggcgat gaagagccga ccctgcgcat
      901 cgccgaacac gctcatcagg ttggcgtcgg cgcgggtttc gcccgggggt ggcggcagct
      961 ccgcctcttc ccaggtccgg ccgccgtcgc gcgtgcgcag catcagcgac cacagcccga
     1021 ccgccacgcc gttgtgcgca tcggtgaagg ccaccgagaa cagcggccgg tcctcgaccg
     1081 agtcgatgcg ctgcacactc caggtctcgc caccgtcggc gctgtgcagg atcaccccga
     1141 gatgccccac cgcccagccc tggcgcgcgt cggcgaagct caccgcggtc agggtcgcgt
     1201 cgaccggcac cgtgccggcc tggcgccagt gcgcgccctc gtcgtcggag agcagcacca
     1261 ccccgcgctc ccccaccgcg accaggcggg tgcccgcgcg ggtcgcgtcg aggatcatgc
     1321 tgcgctcggc gaagggcgag cgcaccgcgg gccgcggcac gaaggcggcg ggatcggtcg
     1381 ccgcgccctg ggcgtgcgca gcgccggccg caagcacgag gctcgcggac acggtcgcgg
     1441 agagcgtcga ggaaagggag ggcgaaaaac aggtcgcgat gcaggtcgcg gagagcagcg
     1501 cgcgcaggtg gcgcagcgtc gacaaagggt tcatttccac tccgcactca atgcgccagg
     1561 atgcccggcg cgcgtaccgg gcccttgcgc ggaaaaaggc gctccatcca caccgcgaag
     1621 gccggcagcg cggtcatcgc catcaccatg ttcaccatga acatgaaggc gagaagcttg
     1681 cccatgtcgg cctggaactt gagctccgag aacatccagg tcgccacgcc cgccgcgagc
     1741 gtgatcgcgg tgaagatcgt ggcggtgccg acctcgagga tggagtgctc gagcgccttg
     1801 acgatgttct ccccgttggc gaggtgcagc tgcaggcggt tgtagatgta gtaggcataa
     1861 tcgacgccga tgccgaccgc cagcaccatc accggcaggg tcgccacggt gaggccgatc
     1921 tcgagctcct tcatgaacca gtagccgatg aaggtgccca cggtcagcgg caggcagcac
     1981 gcgatcaccg cgcggaagtc gcggtacatc atcgccacca gcaccatgat cgccgcgtag
     2041 acatacagca tcatcggcag ctcggacttg tgcacctcct cgttcaccgc cgcctgcacg
     2101 ccggcgttgc ccgaggccag ccggatcgcc agcccgggct cgcgatcgcg ctcgcggaag
     2161 gccttcaccg catcgatcac gcggttgatc gtggtcgcct tgtggtcgga caggaacagg
     2221 tgcaccgcgg tcatgctgca gtccttgttc atgaagccgc gcacgcgccc gatctcggtg
     2281 gcgagcgcgg cgtagttgcc ggggtcgccg ggcaccaccg acatcttcgg gttgccctcg
     2341 ttgtagccct cgttgtaggt gcgcagctgg ccggagaagg acagcgccga cagcacgccc
     2401 ggcacgtact gcatctcggc gacgaagcgg tcctgatagc gccccaccgc gacgtcgtcg
     2461 caggcgtcgg gcggcgcctc gaagatcacc gtgagccagt cgaggccggt gtcgtagctg
     2521 ctggcgatcg acaccgcgtc gcggttgaag cgcgcctccg cgcgcagctc gggcgcgccc
     2581 ggctgcacgg tgccgatgac gcggtcgtgg ctctgccaca ctgccaccgc gaacaccgcc
     2641 agcgtcagcg cgatcacgat cgccgcgttg cgcggctcgg ccacgcgcgc cagcgtgcgc
     2701 agccaggccg agcgcttctc gcgcttgagc acggccttgt cggcgtattc cttggtgaag
     2761 gtgaacagcg aggccgccag cggcagcatc accaggttgg tgacgatctt gtagccgacg
     2821 ccgagcgagg cggtgatcgc gagctcgcgc accatcggga tcgggatcag gatcagcgtg
     2881 atgaaggaca cgaaggcggt gaccagcgcc agcgtgccgg ggatcagcag gccggtgaag
     2941 ctggcgcgcg cggcctcgtc gctcgacttg ccgtgcgaga gctcgcgcac gatgaagttg
     3001 atctgctgca cgccgtgcga gacgccgatc gcgaacacca ggaagggcac cagcacggcg
     3061 agcgggtcga gcccgtagcc gagcagcttc agggtaccga actgccacac cagcgaggtc
     3121 agcgagcaca cgatcggcag cagggtgaag cgcaccgagt ggcagtacca atacaccgcg
     3181 agcgcggtca gcagcagcgc gatcgcgcag aactcgagca ccgccgaggc gccatcggcg
     3241 atgtcgccga tctgcttggc gaagccgatg atctgcacct cgaactgcgc gtcctcgaac
     3301 ttcgcgcgca gcgcctcgag gatgcggttg taggcgacat agtcgagcgc cttgccctcg
     3361 cggtcgcgct cgtgcaactc ggcgacgatc atcgcgctgg tctggtcgcg cgccaccagg
     3421 gtgccgatga agccgccctg gctggccgcg cgctggatgc cggcgatgat ctcgggcgtg
     3481 aggtcgcgcg gcatgatggt gcccgagatc agcggatcgg cgcgaaagcc gtcctcggtg
     3541 atctcgttga cgaaggagtt gggcgtccac agcgactgca cgccgaggcg gtcgacgttg
     3601 ggcaggaagc tcaccgcctg ggtgacctcg tacaggcgct ccagcccggc ctgcgtccag
     3661 atgtcgccgc tgcgcgcctt gaccacgatg ttgagacggt tggcgccgag gacgtcgtcg
     3721 cgatacttgt cgaaggtccg gatgtactcg tggccgatcg gcatctgctt ctcgaagccg
     3781 gcgtccatgc gcagctgcag ggcgtagtag cccatcagcc cggtaaacag catgagcgcg
     3841 accaggatgc tgccccggaa gcgga
//
LOCUS       DAOTIN010000204         3806 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_28446_length_3806_cov_8.906425, whole genome shotgun sequence.
ACCESSION   DAOTIN010000204 DAOTIN010000000
VERSION     DAOTIN010000204.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 3806)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3806)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3806
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_28446_length_3806_cov_8.906425"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..972)
                     /locus_tag="P5537_16615"
     CDS             complement(<1..972)
                     /locus_tag="P5537_16615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002930464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HRV79711.1"
                     /translation="MLSTYQYPKFDYVRPPELDEGRDGHYPVVIVGAGPVGLCTAIDL
                     ARQGRQVLLLDNDDTVSIGSRGVCYAKRTLEVLDRLGCGEEMVQKGVSWNVGRTFFRE
                     DEVFNFNLCPEPDHHRPGMINLQQYYLEDYLVQRARKLPNLEMRFRNSVIAVTPGEDQ
                     ASLRVETPDGTYTLTTDWLVVADGARSPIRTMLGLDIDGKIFMDRFLIADVVMKADFP
                     TERWFWFDPPFHPNQSVLLHRQADNVFRIDFQLGWQADPEHEKKPENVIPRIQAMIGD
                     DREFELEWVSVYTFQCRRMNRFNHGRVLFVGDSAHQVSPFGARGANSG"
     gene            complement(1123..2088)
                     /locus_tag="P5537_16620"
     CDS             complement(1123..2088)
                     /locus_tag="P5537_16620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HRV79712.1"
                     /translation="MSTKKFASQADLEEKQISWEKLSDNAWAYTAEGDPNTGVIIGDD
                     GVMIIDATATPVAAQGVIAKVREITDLPIKYVVLTHYHAVRVLGASGYKGEGLEQIIA
                     SKDTWDLIVERGQQDMDSEIGRFPRLFQAVESVPGLTWPTMTFSGEMTVWMGKLEVRI
                     KQLGRGHTKGDTIVYLPAQDICFSGDLVEADAACYTGDAYLADWPQTLDNLAAMNFAK
                     LVPGRGPALMTPEKVQAGLAYTRDFVSTLYRSAQEAVAKGMDLKATMAHTRANMDPKF
                     GQVFIYEHCLPFDVTRAHDEASGIRDPRIWTAERDQQMWHALQQG"
     gene            2232..3059
                     /locus_tag="P5537_16625"
     CDS             2232..3059
                     /locus_tag="P5537_16625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HRV79713.1"
                     /translation="MQDIPNPSPSTVRDAADSAGERRGIQSIEVGGSLLSALVREGKP
                     MMLKDLAREAGMPAAKAHPYLVSFGKLGLVEQDALTGRYGLGPFALQMGLTALHGLDP
                     IKAALPEAARLADDIDLNVAIAVWGNHGPTVVHIAECSRQIHINMRPGTVMTPLLLSA
                     TGRVFAAFLPQRIVAPVLAAEAVAVSAPPLEMSPGDVHAVLDEIRAHRLARALGNPIP
                     GIHAFSAPVFDAGGQLALALTAMGPVGSVDPDWTGATASRVRAAADAIERQLGKPAG"
     gene            3127..3741
                     /locus_tag="P5537_16630"
     CDS             3127..3741
                     /locus_tag="P5537_16630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004363124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FmdE family protein"
                     /protein_id="HRV79714.1"
                     /translation="MSSERFPAFFDQVPRLLVRDPLAEFLGAAEGGVLEYGYADAVRL
                     AGHSCPTVASAYALAHHALTRLFPGELPVRGLVQVSFQHPLDEGVTGVIAAVVGLLSG
                     SAQDGGFKGIAGRFVRRNLQHFGEHQPLALRFVRSDSGATVHAAAELSKVQPHPEMAE
                     LMRRCMRDEAAPPDAQRFAQLWQDRVRRVLVEHWDDPEVFHLSA"
BASE COUNT          530 a         1299 c         1352 g          625 t
ORIGIN      
        1 gccggagttg gcgccgcgcg cgccgaaggg cgagacctgg tgcgccgagt cgccgacgaa
       61 gagcacgcgg ccatggttga agcggttcat gcggcggcac tggaaggtgt acacgctgac
      121 ccactcgagc tcgaactcgc ggtcgtcgcc gatcatcgcc tggatgcgcg ggatcacgtt
      181 ctcgggcttc ttctcgtgct ccgggtcggc ctgccagccg agctggaagt cgatgcggaa
      241 gacgttgtcg gcctggcggt gcagcagcac cgactggttg ggatggaagg gcgggtcgaa
      301 ccagaaccag cgctcggtgg ggaagtccgc cttcatgacc acgtcggcga tcaggaagcg
      361 gtccatgaag atcttgccgt cgatgtccag cccgagcatg gtgcggatcg ggctgcgcgc
      421 gccgtcggcg accaccagcc agtcggtggt gagcgtgtag gtgccgtcgg gcgtctccac
      481 gcgcaggctc gcctggtcct cgccgggggt gaccgcgatc acgctgttcc tgaagcgcat
      541 ctcgaggttc gggagcttgc gcgcgcgctg caccaggtag tcctcgaggt agtactgctg
      601 caggttgatc atgcccgggc ggtggtggtc gggctcgggg cagaggttga agttgaacac
      661 ctcgtcctcg cggaagaagg tgcggccgac gttccacgac acgcccttct gcaccatctc
      721 ctcgccgcag ccgaggcggt cgagcacctc gagcgtgcgc ttggcgtagc acacgccacg
      781 cgagccgatg gacacggtgt cgtcgttgtc gagcagcagc acctgccggc cctggcgggc
      841 gaggtcgatc gcggtgcaca ggccgaccgg gccggcgccg acgatcacca ccgggtagtg
      901 gccgtcgcgg ccttcgtcga gctcgggcgg acggacgtag tcgaacttgg ggtattgata
      961 cgtgctcagc acggcggtct cctccaggat tgttcgtgtg caccgacgct gcgtcttggc
     1021 gcgcgggcta ccggtacggg gcgccgcgac gggcgcccgg ctctgctgga aatcaggggt
     1081 gcgaaaggcg gggctccaca cggggccccg cggatcgagc gctcagccct gctgcagcgc
     1141 gtgccacatc tgctggtcgc gctcggcggt ccagatgcgc gggtcgcgga tgccgctcgc
     1201 ctcgtcgtgg gcgcgggtga cgtcgaaggg caggcagtgc tcgtagatga agacctggcc
     1261 gaacttcggg tccatgttgg cgcgggtgtg cgccatcgtc gccttgaggt ccatgccctt
     1321 cgcgaccgct tcctgcgcgc tgcgatacag ggtggacacg aagtcgcggg tgtaggcgag
     1381 gccggcctgc accttctcgg gcgtcatcag tgccgggccg cggccgggca cgagcttggc
     1441 gaagttcatc gccgccaggt tgtcgagggt ctgcggccag tcggcgaggt aggcatcgcc
     1501 ggtgtagcag gcggcgtcgg cctcgaccag gtcgcccgag aagcagatgt cctgcgcggg
     1561 cagatagacg atggtgtcgc ccttggtgtg gccgcggccg agctgcttga tgcgcacctc
     1621 gagcttgccc atccacacgg tcatctcgcc gctgaaggtc atggtcggcc aggtcagccc
     1681 gggcacgctc tcgacggcct ggaagaggcg cgggaaacgg ccgatctcgg agtccatgtc
     1741 ctgctggccg cgctcgacga tgaggtccca ggtgtccttg ctggcgatga tctgctccag
     1801 gccctcgccc ttgtagcccg aggcgccgag cacgcgcacc gcgtggtagt gggtcagcac
     1861 gacgtacttg atcggcaagt cggtgatctc gcgcaccttg gcgatcacgc cctgcgcggc
     1921 caccggggtg gcggtggcat cgatgatcat cacgccgtcg tcgccgatga tcacgccggt
     1981 gttggggtcg ccctcggcgg tgtaggccca ggcgttgtcg gacagcttct cccagctgat
     2041 ctgcttctct tcgaggtcgg cctgggaggc gaatttcttg gtgctcatgc gggggctcct
     2101 gtgatgtgcg gcgatgggtg gatactagcc agcgatttgt taatcgtcaa ttcgttcgtt
     2161 atagcttaat tttcggggca cgcagcccgt gcggtggact gttaagatgc gccgcgaatc
     2221 cggagagcag catgcaggac atccctaacc catccccttc gaccgtgcgc gacgcggccg
     2281 attccgccgg cgagcgccgc ggcatccagt ccatcgaggt gggcggcagc ctgctgtccg
     2341 ccctcgtgcg cgagggcaag ccgatgatgc tgaaggacct cgcgcgcgag gccggcatgc
     2401 cggcagccaa ggcgcacccc tacctggtga gcttcggcaa gctcggcctg gtcgagcagg
     2461 acgcgctcac cggccgctac ggcctgggtc cgttcgcgct gcagatgggc ctcaccgcgc
     2521 tgcatggcct cgacccgatc aaggcggccc tgcccgaggc ggcccggctc gccgacgaca
     2581 tcgatctcaa cgtggcgatc gcggtgtggg gcaaccacgg acccaccgtc gtgcacatcg
     2641 ccgagtgcag ccgccagatc cacatcaaca tgcgcccggg tacggtgatg acccccctgc
     2701 tgctgtctgc caccgggcgc gtgttcgcgg ccttcctgcc gcagcgcatc gtcgcccccg
     2761 tgctcgccgc cgaggcggtg gcggtgagcg cgccgccgct ggagatgtct cccggcgacg
     2821 tgcacgcggt gctcgacgag atccgcgcgc accgcctcgc gcgcgcgctc ggcaatccca
     2881 tcccgggcat ccacgcgttc tccgcgccgg tcttcgacgc tggcggccag ctcgcgctcg
     2941 cgctcaccgc gatgggaccg gtcggcagcg tcgatccgga ctggacgggc gccaccgcca
     3001 gccgggtgcg cgcggcggcg gatgcgatcg agcgtcagct gggcaagccg gccggctgag
     3061 ccacatcaag gcgggtgagg tcggcacggg cggagaatcg gcgctccccc acgccccgga
     3121 gcgagcatgt ccagcgaacg tttccccgcc ttcttcgacc aggtgccgcg cctcctggtg
     3181 cgcgatccgc tcgccgaatt cctcggcgcc gccgaggggg gcgtactcga gtacggctac
     3241 gccgacgcag tgcgcctggc cggtcactcc tgcccgaccg tggcctcggc ctacgccctc
     3301 gcccaccacg cgctcacccg gctcttcccg ggcgaactgc cggtgcgcgg cctggtgcag
     3361 gtgagcttcc agcatccgct cgacgaaggc gtgaccggcg tcatcgccgc ggtggtcggc
     3421 ctgctcagcg gcagcgccca ggacggcggc ttcaagggca tcgccggtcg tttcgtgcgc
     3481 cgcaacctgc agcacttcgg cgaacaccag ccgctcgcgc tgcgcttcgt ccgcagcgac
     3541 agcggcgcca cggtgcacgc cgcggccgag ctgtccaagg tgcagcccca ccccgagatg
     3601 gccgagctga tgcgccgctg catgcgcgac gaggccgccc cccccgacgc acagcgcttc
     3661 gcgcagctgt ggcaggaccg cgtgcggcgc gtgctcgtcg aacactggga cgaccccgag
     3721 gtgttccacc tctcggcctg aatcgcggga ctgcgcggcc ccgttcgcgg ctgccgccgc
     3781 tcctacaagg gcttgcacag gcgcgg
//
LOCUS       DAOTIN010000205         3800 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_28510_length_3800_cov_7.827503, whole genome shotgun sequence.
ACCESSION   DAOTIN010000205 DAOTIN010000000
VERSION     DAOTIN010000205.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 3800)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3800)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3800
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_28510_length_3800_cov_7.827503"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1460
                     /locus_tag="P5537_16635"
     CDS             <1..1460
                     /locus_tag="P5537_16635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011764838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="FHIPEP family type III secretion protein"
                     /protein_id="HRV79715.1"
                     /translation="MINILGGLFVGVMQHDMAVGDAAHTYTLLTIGDGLVAQIPSLIV
                     SVAAGLVVSRVGDEGDVGGLVIGQLFSNPQVMVLTAAIIGVLGLIPGMPNLVFLLLAA
                     TLGGMAWMRRKRIAEDAAAAAAPEAAAQVPMPAADNLEASWNDVSQVDVLGLEVGYRL
                     IPMVDKGQDGELLKRIRGLRKKFAQEVGFLSAPVHIRDNLELKPNGYRLALKGVEVGG
                     GEAYPGQFLAINPGRVSGPLAGRETTDPAFGLPAVWIDASMREQAHALGYTVVDASTV
                     VATHLNHVILNHAAELLGRQETQALLDHLGKESPKLVEDLVPKLLPLGTVQRVLQNLL
                     EEGVNIRDMRSIIEVLAENAPRVQDPAQLTTRVREALGRAILQGLFPGNAEVQVMALE
                     PGLERILMQAMAAGGEGGAIEPGLADTLLRQTAQIAQRQEDIGLPPVLLVPAQLRLLL
                     SRFLRRAVPSLKVVSNSEVPENRTIRVTAMVGAQA"
     assembly_gap    1537..1636
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            2015..3499
                     /gene="flhF"
                     /locus_tag="P5537_16640"
     CDS             2015..3499
                     /gene="flhF"
                     /locus_tag="P5537_16640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0044781 - bacterial-type flagellum
                     organization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhF"
                     /protein_id="HRV79716.1"
                     /translation="MNVKRYFAPTAREALRALKEALGPDAIVLSNRAVEGGVEILALP
                     GEAVGALQAANRAAVVARTGGDARPAPAPVPEAPAAATRTADEADFRVSLSALAASAA
                     RNASRSAPQPVAEPAPVVRAFNPPRIETADYALRNRDGVLRAAVAAQASAPRPPASGP
                     AVFSGRAAARPEADEFGSARVRELQETNARLMSELTGIRGMIERQLAGFAWGETRRQA
                     PARAAMLGELLEAGFSAAIARKLVEAVLEDADRIEAREAVGAALDRLMRACASDEDLL
                     DRGGVYALVGPTGVGKTTTTAKLAARCVVRHGAGRLALITTDGYRIGAQEQLRIYGRI
                     LGVPVFSVRDAADLRQTLAGLRNKHMVLIDTMGMSQRDRMVAEQAAMLSGAGDVRRLL
                     LLNATARGDTLDDVVRAYAGDDLAGCIFTKVDEAASLAPALDVAVRHELDIRYLTNGQ
                     RVPEDLHLPNRAYLLHRALREHGSASPWHLQGDEAGMLLAAGGA"
     gene            3502..>3800
                     /locus_tag="P5537_16645"
     CDS             3502..>3800
                     /locus_tag="P5537_16645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar FleN"
                     /protein_id="HRV79717.1"
                     /translation="MLDGREDQAAGLRRLFRRAPPQVVALYAGGRRAADNAALAAHRI
                     AGRSERVLVLDEAEGDATLCGALGVGEGADLLQLLDGRSTLADILQPVPGLVGRVP"
BASE COUNT          503 a         1424 c         1293 g          480 t
ORIGIN      
        1 tgatgatcaa catcctcggc gggcttttcg tcggcgtcat gcagcacgac atggcagtgg
       61 gcgacgccgc ccacacctac accctgctca ccatcggcga cggcctggtg gcgcagatcc
      121 cctcgctgat cgtctcggtg gcggccggtc tggtggtgtc gcgggtgggc gacgagggcg
      181 acgtcggcgg gctggtgatc ggccagctgt tctcgaatcc gcaggtcatg gtgctgaccg
      241 cggcgatcat cggcgtgctc ggcctgatcc ccggcatgcc caacctggtc ttcctgctgc
      301 tcgccgccac gctcggcggc atggcgtgga tgcggcgcaa gcgcatcgcc gaggacgccg
      361 cggccgccgc cgcgcccgag gccgccgcgc aggtgccgat gcctgccgcc gacaacctgg
      421 aggcgagctg gaacgacgtc tcgcaggtgg atgtgctcgg cctcgaggtc ggctaccgcc
      481 tcatcccgat ggtcgacaag ggccaggacg gcgaactgct caagcgtatc cgcggcctgc
      541 gcaagaagtt cgcccaggag gtcggcttcc tgtccgcgcc cgtgcacatc cgcgacaacc
      601 tcgagctcaa gcccaacggc taccgcctcg cgctcaaggg cgtcgaggtc ggcggcggcg
      661 aggcctatcc cggccagttc ctcgccatca acccgggccg cgtctccggc ccgctcgccg
      721 ggcgcgagac caccgacccc gccttcggcc tgcccgcggt gtggatcgac gccagcatgc
      781 gcgagcaggc gcacgcgctc ggctacaccg tggtggacgc gagcacggtg gtcgccaccc
      841 acctcaacca cgtcatcctc aaccacgccg ccgagctgct cggacgccag gagacccagg
      901 ccctgctcga ccacctcggc aaggagtcgc ccaagctggt cgaggacctc gtgcccaagc
      961 tgctgccgct cggcaccgta cagcgcgtgc tgcagaacct gctcgaggag ggcgtcaaca
     1021 ttcgcgacat gcgcagcatc atcgaggtgc tcgccgagaa cgcgccgcgc gtgcaggacc
     1081 ccgcccagct cacgacccgc gtgcgcgagg cgctgggccg tgcgatcctg cagggactgt
     1141 tcccggggaa tgccgaggtc caggtcatgg cgctcgagcc cggcctggag cgcatcctca
     1201 tgcaggccat ggctgcgggc ggcgagggtg gggcgatcga gcccggcctc gccgacaccc
     1261 tgctgcgcca gaccgcacag atcgcccagc gccaggaaga catcggcctg ccgccggtgc
     1321 tgctggtgcc cgcgcagctg cgcctgctgc tgtcgcgctt cctgcgccgc gccgtgccct
     1381 cgctcaaggt cgtctccaac agcgaggtgc ccgagaaccg caccatccgc gtcaccgcga
     1441 tggtgggcgc gcaggcctga gcgtcccagc ccgagcccgc cttcgcgcct gccggcgctc
     1501 ctacagcaac cgccgcggtt ccgtcccatg taggagnnnn nnnnnnnnnn nnnnnnnnnn
     1561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1621 nnnnnnnnnn nnnnnnttcc tcccgcgacg cgggcgacgc agcccgcccg cgggttcgcg
     1681 cctgccggcg ctcctacagc aaccgccgcg gttccgtccc atgtaggagc ggcggcagcc
     1741 gcgaatgcgg cgcttcctcc cgcgacgcgg gcgacgcagc ccgcccgcgg gttcgcgcct
     1801 gccggcgcgc ctgcagcaac cgccgcgcct ccccgacgtg taggagcggc ggcagccgcg
     1861 aacgggcgat cgaagccgcc gccgcgatcc ggcctgctgc atcgtcggcc gaataggcgc
     1921 gggaaacccg ctttattcga accctggcga ttgacgcccg ctggcgataa tccacatcaa
     1981 gcagtggtcg acgccgacca ccgggagaat cgccatgaac gtcaaacgct actttgcccc
     2041 caccgcccgc gaggcgctcc gtgcgctcaa ggaagccctc ggcccggacg cgatcgtgct
     2101 ctccaaccgc gccgtcgaag gtggggtgga gatcctcgcg ctgccgggcg aggcggtcgg
     2161 agcgctgcag gcggccaacc gcgcggcggt ggtggcgcgc acgggcgggg atgcccgacc
     2221 cgcacccgca ccggtgcccg aggcgccggc ggcggcgacg cgcacggccg acgaagcgga
     2281 ttttcgcgtg agcctctcgg cgctggcggc cagcgcggcg cgcaacgcct cccgttccgc
     2341 cccccagccg gtcgccgagc cggcgcccgt ggtgcgcgcc ttcaacccgc cgcgcatcga
     2401 gaccgccgac tacgcgctgc gcaaccgcga cggcgtgctg cgcgcagcgg tcgccgccca
     2461 ggcctccgct ccgcgcccgc ccgcgagcgg cccggcggta ttctcgggtc gcgccgccgc
     2521 ccgtcccgag gctgacgagt tcggcagcgc gcgcgtgcgc gagctgcagg aaaccaacgc
     2581 ccgcctcatg tccgagctca ccggcatccg cggcatgatc gagcgccagc tcgcaggctt
     2641 cgcctggggc gagacgcgcc gccaggcgcc ggcgcgcgcg gccatgctcg gcgaactgct
     2701 cgaggccggc ttctccgcgg cgatcgcgcg caagctggtc gaggccgtgc tcgaggacgc
     2761 cgaccgcatc gaggcgcgcg aggcggtggg tgccgcgctc gatcgcctga tgcgggcctg
     2821 cgcgtccgac gaggacctgc tcgaccgcgg cggcgtgtat gccctggtcg gcccaaccgg
     2881 ggtcggcaag accaccacta ccgccaagct cgccgcacgc tgcgtggtcc gccacggcgc
     2941 cggccggctc gcgctgatca ccaccgacgg ctaccgcatc ggcgcccagg agcagctgcg
     3001 catctacggc cgcatcctcg gcgtgccggt gttctcggtg cgcgatgccg cggacctgcg
     3061 ccagaccctg gccggcctgc gcaacaaaca tatggtgctg atcgacacca tgggcatgag
     3121 ccagcgcgac cgcatggtgg ccgagcaggc agccatgctc tccggtgccg gcgacgtgcg
     3181 caggctgctg ctgctcaacg ccaccgcgcg cggtgacacc ctggacgacg tggtgcgcgc
     3241 ctacgccggc gacgatctcg ccggctgcat cttcacgaag gtggacgagg ccgcctcgct
     3301 cgcgcccgcg ctcgacgtcg cggtgcgcca cgagctcgac atccgctacc tcaccaacgg
     3361 ccagcgcgtg cccgaggacc tgcatctgcc caaccgcgcc tacctgctgc accgcgcgct
     3421 gcgcgagcac ggcagcgcgt cgccctggca cctgcagggc gacgaggccg gcatgctgct
     3481 cgcggcagga ggggcctgag catgctcgac ggacgcgagg accaggcggc gggcctgcgc
     3541 aggctgttcc gccgcgcgcc gccccaggtg gtggcgctgt acgcgggcgg ccgccgtgcc
     3601 gccgacaacg ccgcgctcgc cgcccaccgc atcgcggggc gcagcgagcg cgtgctggtg
     3661 ctggacgagg ccgagggcga cgccacgctg tgtggcgcgc tcggcgtggg cgagggtgcg
     3721 gacctgctgc agctgctcga cggccgcagc acgctcgccg acatcctgca gccggtgccc
     3781 ggcctggtcg gccgcgtgcc
//
LOCUS       DAOTIN010000206         3638 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_30190_length_3638_cov_8.406363, whole genome shotgun sequence.
ACCESSION   DAOTIN010000206 DAOTIN010000000
VERSION     DAOTIN010000206.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 3638)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3638)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3638
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_30190_length_3638_cov_8.406363"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(166..732)
                     /locus_tag="P5537_16650"
     CDS             complement(166..732)
                     /locus_tag="P5537_16650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004389020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2796 domain-containing protein"
                     /protein_id="HRV79718.1"
                     /translation="MPTRLRLSLLTGLLALALPAAALAQHAHGAHEHGVADLTVALEG
                     RMLQIELISPLDNLVGFEHAPENEAQRAVLADAERRLLDGEAMFAFSAEAGCAIREVE
                     IESPWPQSGRNHDHGHAHDHAQPTRGDHEDMVVSYGFECAHPEALRRLELRAFAHFPR
                     LQRVRAEFATPRGQGAGVLTPNAAALAL"
     gene            912..1370
                     /locus_tag="P5537_16655"
     CDS             912..1370
                     /locus_tag="P5537_16655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HRV79719.1"
                     /translation="MPPHAQPAAADSARELIAARGGRVTRTRVAVIEALQRSAHPLSH
                     DEIGATLDGAGIGHDRVTLYRALDWLVEQGIAQRIAGGERAWRFEIRRDGDHRHAHFH
                     CERCGQIVCLEDVPAAAPALPAGFAVARAELVLHGACADCGRAGVEGKKE"
     gene            1367..1600
                     /locus_tag="P5537_16660"
     CDS             1367..1600
                     /locus_tag="P5537_16660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002944466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79720.1"
                     /translation="MRPTETAYRPQGQPAPVRPAGPGLRPAVRVPRGADEHAEDAHPL
                     PARSLLGAGLAARLAVVTGALALLWTTVLWALR"
     gene            1597..2499
                     /locus_tag="P5537_16665"
     CDS             1597..2499
                     /locus_tag="P5537_16665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011764377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV79721.1"
                     /translation="MNRLALPMIRLDNLTLGYDRHPAVHHLSAEIPAGALVAVVGPNG
                     AGKSTLLKGLAGELHPIGGRIVLPELPAGGLAYMPQRGEIDHSFPVSVFDVVAMGLWH
                     EIGAFGGLSREQRGRVRAALAAVGMAGFEARPIGSLSGGQLQRARFARLMLQDAPLIL
                     LDEPFAAIDSRTVDDLVELILGWHDEGRTILTVVHDLEQVRRHFPTALLLSREPVAFG
                     PTAEVLTPERLARARRLSEAFDEHAHECQIEELTVAVAPDVGTHPHTHDDGHGHTEGH
                     GHAPVHPAAHAHLAPRPRRGLPRH"
     gene            2535..3401
                     /locus_tag="P5537_16670"
     CDS             2535..3401
                     /locus_tag="P5537_16670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HRV79722.1"
                     /translation="MFDLLISPFTEFAFMRRALAGCLALALGATPVGVFLLLRRMSLM
                     GDAMSHAILPGAALGYLAFGLSLGAMTVGGIVAGLVVVFAAGLVTRASVLKEDASLAA
                     FYLLSLAAGVMIVSLRGQNLDLLHVLFGSVLGLDDASLLLIASIASVTLASLALLFRP
                     LVMECFDPAFLRGVSRWSPVAHYGFLMLVVVNLVSGFHALGTLMAVGIMILPSAAARL
                     WAKGLPMLLLLAVLFAFGSGASGLLLSFHADVPAGPAIVLVCGVVYFVSLLAAPGGLL
                     AGRLPVRHHLES"
BASE COUNT          429 a         1351 c         1320 g          538 t
ORIGIN      
        1 gcagcgtggt cttgccgctg ccgctggggc cgcgcaggaa ggcacgctcg cccgcaccga
       61 gctgcagcgc gtcgatcgcc aggcagtcgt gcgcgccgcc cggccagcga tagcgcaggc
      121 cggcgaggcg cacggccggc gcaagttcgg cgcgcccggc tgcgctcaca gcgcgagcgc
      181 ggccgcgttc ggggtgagca cgccggcccc ctggccgcgc ggggtggcga actcggcgcg
      241 cacgcgctgc aggcgcggga agtgcgcgaa ggcgcgcagc tcgagccggc gcagggcctc
      301 ggggtgggcg cactcgaagc cgtagctcac caccatgtcc tcgtggtcgc cgcgggtcgg
      361 ctgggcatga tcgtgggcgt ggccgtggtc gtgattgcgc ccgctctgcg gccagggcga
      421 ctcgatctcc acctcccgga tcgcgcagcc ggcctcggcg ctgaaggcga acatcgcctc
      481 gccgtcgagc aggcggcgct cggcgtcggc gagcacggcg cgctgcgcct cgttctccgg
      541 tgcatgctcg aagccgacga ggttgtcgag tggcgagatc agctcgatct ggagcatgcg
      601 gccctccagc gcgacggtga gatccgcgac gccgtgctcg tgagcgccat gcgcatgctg
      661 tgcgagcgcg gcggcaggaa gggcgagggc gaggaggccg gtgaggaggg atagacgaag
      721 gcgggtcggc atgatcgtgg gtcgtggcgc ggaacgaatc gggatgcgtt ggcagcggga
      781 acgcgtgggg cgcgccggaa gccttgcagc gcgggccacg caaatctaat gctacaatgt
      841 tgcatcaaaa gcggcctcgc cgctacaagc ccgaattccc cgccaccgct ccgcacgcaa
      901 caggatcccg catgcccccg cacgcgcagc ccgccgccgc cgactccgcc cgcgaactca
      961 tcgccgcgcg tggcggtcgc gtcacgcgca cgcgggtggc ggtgatcgag gccttgcagc
     1021 gcagcgcaca cccgctctcg cacgacgaga tcggcgccac gctcgacggt gcgggcatcg
     1081 gccacgaccg cgtcaccctc taccgcgcgc tcgactggct ggtggaacag ggcatcgcgc
     1141 agcgcatcgc cgggggcgag cgcgcctggc gcttcgagat ccgccgcgat ggcgaccacc
     1201 gccacgccca cttccactgc gagcgctgcg gccagatcgt ctgcctggag gacgtgcctg
     1261 ccgccgcccc ggcgctgccc gccggcttcg cggtggcacg cgccgagctg gtgctgcatg
     1321 gcgcctgcgc cgattgtggc cgtgccggcg tggaggggaa gaaagaatga ggccgaccga
     1381 aaccgcctac cgcccgcaag ggcagcccgc gccggttcgt ccggcaggcc cgggcctgcg
     1441 tcccgccgtc cgcgtccccc gcggcgccga cgagcacgcg gaggacgctc accccttgcc
     1501 ggcacgcagc ctgctcggcg ccggtctcgc tgcccgcctc gccgtggtca ccggcgcgct
     1561 cgcgctgctg tggacgaccg tgctgtgggc gctgagatga atcgcctcgc gctaccgatg
     1621 atccgcctcg acaacctcac cctgggctac gaccgccacc cggcggtgca ccacctgtcg
     1681 gccgagatcc cggcgggcgc gctggtcgcc gtggtgggac ccaacggcgc aggcaagtcc
     1741 accctcctca agggcctcgc cggcgagctg cacccgatcg gcgggcgcat cgtactgccc
     1801 gagctgccgg cgggcggcct ggcctacatg ccgcagcgcg gcgagatcga ccacagcttc
     1861 ccggtgtcgg tgttcgacgt ggtggcgatg ggcctctggc atgagatcgg tgcctttggc
     1921 gggctgtcgc gcgagcagcg cggtcgcgtg cgtgccgcgc tcgccgcggt gggcatggcg
     1981 ggcttcgagg cgcgcccgat cggctcgctg tcgggcggcc agctgcagcg cgcgcgcttc
     2041 gcccgcctga tgctgcagga cgcgccgctg atcctgctcg acgagccctt cgcggcgatc
     2101 gacagtcgca cggtcgacga cctcgtcgag ctcatcctcg gctggcacga cgagggtcgc
     2161 accatcctta ccgtggtgca cgacctcgag caggtgcgcc gccacttccc caccgcgctg
     2221 ctgctgtcgc gcgaaccggt ggccttcggc cccaccgccg aggtgctcac gcccgagcgc
     2281 ctggcgcgcg cgcgccgcct ctccgaagcc ttcgacgagc acgcgcacga gtgccaaatc
     2341 gaggagctga cagtagccgt ggcgcccgat gtcggcacgc atccgcacac gcacgacgac
     2401 gggcacggcc acaccgaggg ccacggccac gcgcctgtgc acccggcggc gcacgcgcac
     2461 ctggcgccgc ggccgcgtcg cggccttccc cgccactgaa tccgcagccc gctgcgcgta
     2521 gcccaggccc caccgtgttc gacctcctga tctccccctt caccgagttc gccttcatgc
     2581 gccgcgcgct cgccggctgc ctggcgctcg cgctcggcgc cacgccggtg ggcgtgttcc
     2641 tgctgctgcg ccgcatgagc ctgatgggcg acgcgatgag ccacgccatc ctgcccggcg
     2701 ccgcgctcgg ctacctcgca ttcggcctgt cgctgggggc gatgacggtc ggcggcatcg
     2761 tcgccgggct ggtggtcgtg ttcgcggcgg ggctggtgac gcgcgcctcg gtgctcaagg
     2821 aggacgccag cctggccgcc ttctacctgc tctcgctcgc cgcgggggtg atgatcgtgt
     2881 cgctgcgcgg gcagaacctc gatctgctgc acgtgctgtt cggctccgtg ctcgggctcg
     2941 acgacgcctc gctgctgctc atcgcgagca tcgccagcgt gaccctggcg agcctggcgc
     3001 tgctgttccg cccgctggtc atggagtgct tcgaccccgc cttcctgcgc ggggtgagcc
     3061 ggtggtcgcc ggtggcgcac tacggcttcc tgatgctggt ggtggtgaac ctggtgagcg
     3121 gcttccacgc gctcggcacg ctgatggcgg tgggcatcat gatcctgccc tcggccgcgg
     3181 cgcgcctgtg ggcgaagggt ctgccgatgc tgctgctgct cgcggtgctg ttcgccttcg
     3241 gcagcggcgc gagcgggctg ctgctgtcct tccacgccga cgtgccagcc gggccggcga
     3301 tcgtgctggt gtgcggcgtg gtgtatttcg tctcgctgct cgccgccccc ggtggcctac
     3361 tcgctggccg gctaccggtg cggcaccacc tggagtcgtg accgccttcg cgccgacgag
     3421 gggcggcggt gcttccggaa ctgctggttc gcacctgccg gcgctcctac agggcgttcc
     3481 cggcggcaca cgcgtccgcc gcgcgcagcc tcctgtgcgc cgacgagggg cggcggtgct
     3541 tccggaactt ctggttcgcg cctgccggcg ctcctacagg gcgttcccgg cggcacacgc
     3601 gtccgccgcg cgcagcctcc tgtgcgccgg cgaggggc
//
LOCUS       DAOTIN010000207         3612 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_30462_length_3612_cov_9.538375, whole genome shotgun sequence.
ACCESSION   DAOTIN010000207 DAOTIN010000000
VERSION     DAOTIN010000207.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 3612)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3612)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3612
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_30462_length_3612_cov_9.538375"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..2992)
                     /locus_tag="P5537_16675"
     CDS             complement(<1..2992)
                     /locus_tag="P5537_16675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HRV79723.1"
                     /translation="MSKPRRGVFERPLAQALIAALLVFGLLAAFLLFSHRSADAITST
                     AARNEVRVLATQIEGALRRIEMSIGFLHDKYVRVGLHENTGTPAWQESLRRLQQDMLY
                     LARDFPEVVAIVVADARGRIQASTLDGPPQWEIQDREYFRDALESGSAALAFSAPLVS
                     KGKSRKVVVAHQAIRDPAGEFVGVVAVALDLQRLQDLLLDVDVGRLGMVSIRRSDEGS
                     LVLRWPEHNASQVADFTSTRPFQAIRRGELSGSARYVGIVDEVERSFAFQALHGYPFY
                     VVIGRATSEQFAPWRQTALVASIIALTTLALLLAMQFRLHRSRRQLARTKRDFDALID
                     SREEAICAWLPDTTLLSCNERYAELRGAEATSLPGTRWIDSVPEQKREATLGAIGQML
                     QGAGTLTTDRRVRQADGSSRWLRWLDLPVFDEDGRCVEIRSIGQDITAHKEAELRLRQ
                     LALAVEQSPNAIVITDTAGHIEYVNEAFERTTGYTAAEAIGHNPRILNAGKTPAATYA
                     DLWATLSRGEVWRGEFVNTRKDGGTYTELATIAPIKQADGGVSHYVAIKEDITERREA
                     EARIRQLAFYDTLTGLPNRSLMWDRLRHAIAASARSGSNAMLLLLDLDHFKLLNDTQG
                     HHAGDALLREVARRLRAALREEDTVARLGDDDFAIVVENLGEDRDEAIAHAEKIAEHL
                     HRAVTAPCELGLASGAYHVGASLGLTLFRGRAATADAVLKQAEVAVARAKDDGRNLIR
                     FFSEAMQAVVAARAELELKLRAALAGNGFRLYYQPQLDRDGRVIGAEALIRCFDADGA
                     MISPAAFIPLAEETGLIVPIGEWVLETACAQLRAWQREPATAALTLSINVSARQFHQP
                     DFVGKVAAAIERSRIHPGGLKIELTESVVIGDIETTVLRMRQIKALGVRFALDDFGTG
                     YSSLSYLKRLPFDQLKIDQVFVRDMEKDTSSEAIVRAILAISRSLELEVVAEGVETAA
                     QHELLLTRGCELFQGYLFGRPVPIE"
     gene            complement(3121..3429)
                     /locus_tag="P5537_16680"
     CDS             complement(3121..3429)
                     /locus_tag="P5537_16680"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79724.1"
                     /translation="MSMTTGTLGQAGGLVGDLTGDAGGVVRGVGGERVEPDRGEALAH
                     GGVTQVLRADAVAVRVGEGRVGGARAAERGVELEVAATMPRVWRTHARICGGGRDKVQ
                     "
BASE COUNT          513 a         1261 c         1288 g          550 t
ORIGIN      
        1 cctcgatcgg gaccggcctg ccgaacagat agccctggaa cagctcgcag ccgcgcgtga
       61 gcagcagctc atgctgggcg gcggtctcga cgccctcggc caccacctcg agctcgagcg
      121 agcggctgat cgccaggatc gcgcgcacga tggcctcgct gctggtgtcc ttctccatgt
      181 cgcgcacgaa gacctggtcg atcttgagct ggtcgaaggg caggcgcttg agataggaca
      241 gcgaggagta gccggtgccg aagtcgtcga gcgcgaagcg cacgccgagg gccttgatct
      301 gccgcatgcg cagcaccgtg gtctcgatgt cgccgatcac cacgctctcg gtgagctcga
      361 tcttgaggcc gcccgggtgg atgcggctgc gctcgatcgc cgccgcgacc ttgccgacga
      421 agtcgggctg gtggaactgg cgcgcgctga cgttgatcga cagcgtcagc gcggccgttg
      481 ccggctcgcg ctgccaggcg cgcagctgcg cgcaggcggt ctccagcacc cactcgccga
      541 tcggcacgat gagcccggtc tcctcggcga gcgggatgaa ggcggcgggc gagatcatcg
      601 cgccgtcggc gtcgaagcag cggatcagcg cctcggcgcc gatcacgcgg ccgtcgcgat
      661 cgagctgcgg ctggtagtac aggcggaagc cgttgccggc cagggccgcg cgcagcttga
      721 gctcgagctc ggcgcgcgcg gccaccaccg cctgcatcgc ctcgctgaag aagcggatca
      781 ggttgcggcc gtcatccttg gcgcgcgcca ccgccacctc ggcctgcttg agcaccgcgt
      841 cggcggtcgc cgcgcggccg cggaacaggg tcaggcccag gctcgcgccg acgtggtagg
      901 caccgctcgc gaggccgagc tcgcagggcg cggtcacggc gcggtgcagg tgctcggcga
      961 tcttctcggc gtgggcgatc gcctcgtcgc ggtcctcacc gaggttctcg accacgatcg
     1021 cgaagtcgtc gtcgcccagc cgcgccaccg tgtcctcctc gcgcagcgcg gcgcgcaggc
     1081 ggcgcgccac ctcgcgcagc agggcgtcgc cggcgtggtg gccctgggtg tcgttgagca
     1141 gcttgaagtg gtcgaggtcg agcagcagca gcatggcgtt cgatccgctg cgcgcgctgg
     1201 cggcgatggc gtggcgcagg cggtcccaca tcaggctgcg gttgggcagg ccggtgaggg
     1261 tgtcgtagaa cgcgagctgg cggatgcgcg cctcggcctc gcggcgctcg gtgatgtcct
     1321 ccttgatcgc cacgtagtgg ctgacgccgc cgtcggcctg cttgatcggc gcgatcgtgg
     1381 ccagttccgt ataggtgccg ccgtccttgc gggtgttcac gaactcgccc cgccacacct
     1441 cgccgcggct cagggtggcc cacaggtcgg cataggtggc ggccggggtc ttgccggcgt
     1501 tgaggatgcg cgggttgtgc ccgatcgcct ccgcggcggt gtagccggtg gtgcgctcga
     1561 aggcttcgtt gacgtattcg atgtgacccg cggtgtcggt gatcacgatt gcgttcgggc
     1621 tctgctcgac cgcgagcgcg agctggcgca ggcgcagctc ggcctccttg tgcgcggtga
     1681 tgtcctggcc gatcgagcgg atctcgacgc agcgcccgtc ctcgtcgaac accggcagat
     1741 ccagccagcg cagccagcgc gagctgccgt cggcctggcg gacgcggcgg tcggtggtga
     1801 gcgtgcccgc gccctgcagc atctggccga tggcgcccag ggtcgcttcg cgcttttgct
     1861 ccggaacact gtcgatccag cgcgtgcccg gcagcgacgt ggcctcggcg ccgcgcagct
     1921 cggcatagcg ctcgttgcac gacagcagcg tggtgtctgg cagccaggcg cagatcgcct
     1981 cctcgcggct gtcgatcagg gcgtcgaaat cacgtttggt gcgcgcgagc tgccggcggc
     2041 tgcgatgcag cctgaactgc atcgccagca gcagcgccag cgtcgtgagc gcgatgatgc
     2101 tggcgaccag cgcggtctgc cgccagggtg cgaactgctc ggacgtggcg cggccgatca
     2161 ccacgtagaa gggatagccg tgcagcgcct ggaaggcgaa gctgcgctcg acttcgtcca
     2221 cgatgccgac gtagcgcgcg ctgccggaca gctcgccgcg gcggatggcc tggaagggcc
     2281 gggtgctggt gaagtccgcg acctggctgg cgttgtgctc cggccagcgc agcaccaggc
     2341 tgccttcgtc gctgcgccgg atgctgacca tgcccaggcg cccgacgtcc acatccagca
     2401 gcaggtcctg caggcgctgc aggtcgagcg cgaccgcgac cacgccgacg aattcgcccg
     2461 ccggatcgcg gatcgcctga tgggcgacca ccaccttgcg cgacttgccc ttggacacga
     2521 gcggcgcgga gaacgcgagc gccgccgatc cgctctcgag agcatcgcgg aaatactctc
     2581 gatcctggat ctcccattgc ggcggcccgt cgagcgtgct cgcctggatc ctgccgcggg
     2641 cgtcggcgac cacgatcgcg accacctccg gaaagtcgcg ggccaggtac agcatgtcct
     2701 gctgcagccg tcgcagcgac tcctgccagg cgggcgtacc cgtgttctcg tgcaggccga
     2761 cgcggacgta cttgtcgtgc aggaagccga tgctcatctc gatccgcctc agcgcgccct
     2821 cgatctgcgt ggccagcacg cgcacctcgt tgcgtgcggc cgtgctcgtg atcgcgtcgg
     2881 cggagcggtg ggagaacagc aggaaggcgg cgagcagccc gaacaccagc agcgccgcga
     2941 tcagggcctg tgccagcggc cgctcgaaga cgccgcgccg tggcttgctc atcgataccc
     3001 ctgcgcacct gcgcggcgca gcggcgcccg gatcggaacg aggaggcgac gcgcggaatc
     3061 ggacatgaaa agcgatcggg cagggaactg cgcgcaatta tccggacggc agcgtatcgg
     3121 tcactgcact ttgtcacgac caccgccgca aatcctggca tgcgttcgcc acacgcgcgg
     3181 catggtggcc gcaacctcga gctctacgcc gcgttcagcc gctcgggcgc cacctacacg
     3241 cccttccccg acccgcacag ccaccgcatc cgcccggagg acctgcgtga cgccgccgtg
     3301 cgcgagcgcc tcgccacggt ctggctcgac ccgctcgccc ccgaccccgc gcaccacgcc
     3361 gcccgcgtca cccgtgagat cgccgaccag cccgcccgcc tggccgagtg tgccggtcgt
     3421 catcgacacg aatgtattcg tcgcagccct gcgctcggca ggcggtgcgt cacgacaggg
     3481 aaaccgggga ggggaaagaa accggggagg caccccgatt tcagcggagg gcggcacgcg
     3541 cgtcgtgttc gggatggcct tgttcgcagc tgccgcagct cctacagggg atcggagacg
     3601 cggcggtttc tg
//
LOCUS       DAOTIN010000208         3541 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_31294_length_3541_cov_6.035571, whole genome shotgun sequence.
ACCESSION   DAOTIN010000208 DAOTIN010000000
VERSION     DAOTIN010000208.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 3541)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3541)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3541
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_31294_length_3541_cov_6.035571"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            82..495
                     /gene="fliS"
                     /locus_tag="P5537_16685"
     CDS             82..495
                     /gene="fliS"
                     /locus_tag="P5537_16685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HRV79725.1"
                     /translation="MFGGFQQNRAAAYAKVSVETGVNTADPHRLILMLFDGALLQVRT
                     AGIAMQSKDIPGKGMAVSKAIEIIINGLKVSLDMNAGGELAERLAALYDYMSERLLYA
                     NLHNSQPALDEVAGLLATLREAWAGIAGQVKTAAA"
     gene            515..859
                     /locus_tag="P5537_16690"
     CDS             515..859
                     /locus_tag="P5537_16690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HRV79726.1"
                     /translation="MLTRPTLDALLARYEAMAEAARANDWDRLAALEREAAALRDTAR
                     LGADATADAAAMATLPAAEADALRVGIERLLALDAEIRTHTDPFLASVRKLLAGGRQE
                     RAVRNAYGALAP"
     gene            906..>2098
                     /locus_tag="P5537_16695"
     CDS             906..>2098
                     /locus_tag="P5537_16695"
                     /inference="COORDINATES: protein motif:HMM:NF014207.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HRV79727.1"
                     /translation="MIPADLAARLRLINEASFFNTEPPVAGLQRAREIQAQLPELVPG
                     QRFFATLQRTLPDGTFRALVAGQQMTLSLNSAAKSGDTLELEVSQVTPRAVFARIVGG
                     ETAAANTASAQPALSQTGRLISFLLTGQPTPQPASLAGNEPLLNAPPTNGTQLVPLLR
                     QALGQSGLFYESHQAQWVLGKLDTAALLREPQGQQSAPGVGAGAGAGQPGTGASTNAT
                     GQAATATANATPSTPAAPAAQSAATAAARIAGGTDDTAQLNATRSPASLRAGVEEAAP
                     VRAQPIPERLMPVVHQQLDALATQQYVWQGQAWPGQPIEWVIEDPQGEGSREGEDAEP
                     TWNTTLRLTMPRLGGVEAQLHLTPAGVALRLRADDPATIHALDAGGAALASALEAANL
                     KLTGLV"
     assembly_gap    2099..2198
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <2199..2623
                     /locus_tag="P5537_16700"
     CDS             <2199..2623
                     /locus_tag="P5537_16700"
                     /inference="COORDINATES: protein motif:HMM:NF027067.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type II toxin-antitoxin system MqsA family
                     antitoxin"
                     /protein_id="HRV79728.1"
                     /translation="FVQGAVTMKCPCCGAAELIHDTRDLPYLYKGETTTIPAVTGDFC
                     PACGEVILNREHGDRYSELLGQFQRQVNAAYVDPDFIARVRKKLDLDQRQAAEIFGGG
                     VNAFSRYENGKTKPPLALVKLLKVLERHPDLLDEIRAA"
     gene            2752..3531
                     /locus_tag="P5537_16705"
     CDS             2752..3531
                     /locus_tag="P5537_16705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004385799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar brake protein"
                     /protein_id="HRV79729.1"
                     /translation="MTIDHEDTRIELIHADDEAKYVLRDAREILAVLRNLVGARALVS
                     ARLAPGNESVLSTLVEVAEDGSSLLLDGSADALQNQRMEHADALDCVTQLDKVRIQFL
                     LRGQRLVEDGGSPGLRAPPPDALLRLQRREFYRLQTPISEAVSCTLALPRVDGSRREA
                     ELRILDISGGGVAIAVPPVGVHFEPGTEFPDSLLRLPDTAPIPARLVVRNLFRITRRG
                     GAEVLRAGCEFADLPRGAEDAIQRYILRVERTRNARERGRL"
BASE COUNT          580 a         1334 c         1100 g          427 t
ORIGIN      
        1 ccagcaacta tctgacccag cagctcgcca gcctgtcgag cttcgcctaa cccacggaac
       61 ccagacggag accccccaaa catgttcggt ggattccagc aaaaccgcgc cgccgcctac
      121 gccaaggtaa gcgtcgaaac cggcgtcaac accgccgacc cacacaggct gatcctgatg
      181 ctgttcgacg gtgccctgct gcaggtgcgc accgccggca tcgcgatgca gagcaaggac
      241 attcccggca agggcatggc cgtgtccaag gcgatcgaga tcatcatcaa cggcctcaag
      301 gtgagcctgg acatgaacgc tggcggcgag ttggccgagc gcctggcagc cctctacgac
      361 tacatgagcg agcgcctgct ctacgccaac ctgcataaca gccagcccgc gctggacgag
      421 gtggccgggc tgctcgccac cctgcgcgaa gcctgggccg gcatcgccgg gcaggtgaag
      481 acggctgccg cttgagcaac tgaggcccgc agccatgctc acccgcccaa ccctcgacgc
      541 cctgctcgcc cgctacgaag ccatggccga ggcagcgcgc gcgaacgact gggaccgcct
      601 cgccgccctc gagcgcgagg cggcggcgct gcgcgacacc gcgcgactcg gcgccgatgc
      661 aaccgccgac gccgcagcca tggcgaccct gcccgccgcc gaagccgacg ccctgcgcgt
      721 cggcatcgag cgcctgctgg cgctggacgc cgagatccgc acccacaccg accctttcct
      781 cgccagcgtg cgcaagctgc tcgccggcgg ccgccaggaa cgtgcggtgc gcaacgccta
      841 cggcgcgctc gcgccctgac ccgcgcgcgg gctgatcgaa cgccggccac gcaggagccc
      901 ccgcgatgat ccccgccgac ctcgctgccc gcctgcgcct gatcaacgaa gccagcttct
      961 tcaacaccga accgccggtt gcgggcctgc agcgtgcgcg cgagatccag gcccaactgc
     1021 ccgagctcgt ccccggccag cgcttcttcg ccaccctgca gcgcaccctg cccgacggca
     1081 ctttccgcgc gctggtggcc ggacagcaga tgacgctgtc actcaacagc gcggccaagt
     1141 cgggcgacac gctcgagctg gaggtctcgc aagtcacccc gcgagccgtg ttcgcgcgca
     1201 tcgtcggcgg cgagacggct gcggccaaca ccgcctcggc ccagccggcg ctgagccaga
     1261 ccgggcgcct gatcagcttt ctgctcaccg gccagcccac gccgcagccg gccagcctcg
     1321 ccggcaacga gccactgctg aacgcgccgc ccacaaatgg cacgcagctc gtgccgctgc
     1381 tgcgccaggc gctcgggcag agcgggctgt tctatgaatc gcaccaggcg cagtgggtgc
     1441 tcggcaagct cgacaccgcc gcgctgctgc gcgagccgca gggccagcag tcggccccgg
     1501 gcgtgggcgc aggcgcgggc gccggccagc ccggcacggg cgcttcgaca aacgccaccg
     1561 ggcaggcggc gactgcaacg gccaacgcca cgccttcgac ccccgccgcg cccgcagcac
     1621 aatccgccgc cactgcagcc gcacgtattg ccggtggcac cgacgatacc gcacagctca
     1681 acgccacccg cagccccgcc tccctgcgcg ccggcgtgga agaagccgcg cccgtacgcg
     1741 cgcagcccat ccccgagcgc ctgatgccag tcgtccacca gcaactcgac gcgctggcta
     1801 cccagcaata cgtgtggcag ggccaggcct ggccggggca gccgatcgaa tgggtgatcg
     1861 aagacccgca aggcgaaggc agccgcgagg gcgaggacgc cgagcccacc tggaacacca
     1921 ccctgcgcct gaccatgccg cgcctcggcg gcgtcgaggc gcaattgcac ctgacccccg
     1981 ccggcgtcgc gctgcgcctg cgcgccgatg acccggcgac gatccacgcg ctcgacgccg
     2041 gcggcgccgc gctggcctcg gcgctggaag cggccaacct caagctcacc ggcctggtnn
     2101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnngt ttcgttcaag gagctgtgac
     2221 catgaaatgc ccctgctgtg gagcggctga actcatccac gacacccgcg accttccgta
     2281 cctgtacaaa ggcgaaacca ccacgatccc agcggtcacc ggcgacttct gcccggcttg
     2341 cggcgaagtg atcctgaacc gcgaacacgg cgaccgctac agcgagttgc tggggcagtt
     2401 ccagcgccag gtgaacgccg cctacgtgga ccccgacttc atcgccagag tgcgcaagaa
     2461 gcttgacctg gatcaacgcc aggccgcaga gatcttcggt ggaggcgtca atgctttctc
     2521 ccgctacgaa aatggcaaga ccaaaccgcc gctggccttg gtgaaactac tcaaggtact
     2581 tgaacgccat cccgacctgc tcgacgagat cagagccgcc tgaccctgcc tgccacaact
     2641 ggcgcgagtc gctacgcctt tgcccaacaa ggggccccct ctggtggggc accgtgccgc
     2701 atctcgtgat ataagcggga caacacacgc cggcacctcg ggcacgcacg catgacgatc
     2761 gaccacgaag acacccgcat cgaactcatc cacgccgacg acgaggcgaa gtacgtgctg
     2821 cgcgacgcgc gcgagatcct cgccgtcctg cgcaacctgg tgggcgcgcg ggcgctggtg
     2881 agcgcgcggc tggcgccggg caacgagtcc gtgctgtcca ccctggtcga agtcgccgag
     2941 gacggcagca gcctgctgct cgacggcagc gccgacgccc tgcagaacca gcgcatggag
     3001 cacgccgacg cgctcgactg cgtgacccag ctcgacaagg tgcgcatcca gttcctgctg
     3061 cgcggccagc gcctcgtcga ggacggcggc agcccgggat tgcgcgcgcc gccgcccgac
     3121 gccctgctgc gcctgcagcg gcgcgagttc tatcgcctgc agacgccgat ctcggaagcg
     3181 gtgagctgca cgctggcgct cccccgcgtc gacggcagcc ggcgcgaggc cgagctgcgc
     3241 atcctcgaca tcagcggcgg cggcgtggcg atcgcggtgc cgccggtggg cgtgcacttc
     3301 gagccgggca cggagttccc cgacagcctg ctgcgcctgc ccgacaccgc gccgatcccc
     3361 gcgcgcctgg tcgtgcgcaa cctcttccgc atcacccggc gcggcggcgc cgaggtgctg
     3421 cgcgccggct gcgagttcgc cgacctgccg cgcggcgccg aggatgcgat ccagcgctac
     3481 atcctgcgcg tcgagcgcac ccgcaacgcg cgcgagcgcg gccgcttgtg agcccgccgc
     3541 a
//
LOCUS       DAOTIN010000209         3463 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_32212_length_3463_cov_8.146714, whole genome shotgun sequence.
ACCESSION   DAOTIN010000209 DAOTIN010000000
VERSION     DAOTIN010000209.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 3463)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3463)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3463
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_32212_length_3463_cov_8.146714"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            51..1865
                     /locus_tag="P5537_16710"
     CDS             51..1865
                     /locus_tag="P5537_16710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004303036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     ATP-binding protein/permease"
                     /protein_id="HRV79730.1"
                     /translation="MKPALSPRLVLAAFAALLVVAPLALPAFYVTLLNYIGLYAMVAL
                     GLVLLTGVGGLTSFGQAAFVGLGAYTTALLTTSAELPGWLSWAGGSPWLALVVGLLFT
                     VVVAFLIGKLTLRLSGHYLPLATIAWGLSLYFLFGTMGFLGGHTGLTGIPPISLFGYE
                     LRQGEEVYYLIWLFVLAGVLTTSNLLDSREGRAIRALKGGMVMAEAMGVDTARSRMVI
                     FILAALLACASGWLYAHMQRFVNPTPFGLHIGIEYLFMAVVGGAAHVWGALVGAGVIT
                     VLKQWLQDLLPQLFGTSGNFEVIFFGVLMVLVLHKARGGLWPIVVSGFKRFVPVAVQR
                     QVVDRDAQALPRRELPAAGSLLLEAKAVTRRFGGLLANNNMSLEVRAGEILALIGPNG
                     AGKSTMFNQVSGVDTPTSGEVLFLGESVVGKGSRTIARMGMSRTFQHVRLLPTMSVLE
                     NVAIGAHMRGTSGVLSAAWRMDRAEEARLLAEAARQIERVGLGEHMFDEAGSLALGQQ
                     RILEIARALASDPCLLLLDEPAAGLRYKEKEALGDLLRKLRGEGMGVLLVEHDMDFVM
                     GLVDRVVVMEFGEKIAEGLPEDVQRDPAVLAAYLGGED"
     gene            1865..2632
                     /locus_tag="P5537_16715"
     CDS             1865..2632
                     /locus_tag="P5537_16715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HRV79731.1"
                     /translation="MATKNLTDRPVLRVEGLCVSYGKVEALTDASITVGEGQIVTVIG
                     PNGAGKTTMLSAIMGLLPSRGRIEFDSVAMVAPEVETMVASGMNLVPEKRELFGEMSV
                     EDNLVLGAFQRYRMGLRDHAQTMEEIYTLFPRLRERRTQMAGTLSGGERQMLAVGRAL
                     MAKPKLLMLDEPSLGLAPLITREIFRIITQLRSRGVSILLVEQNARAALQVADYAYVL
                     ETGGVAMEGPASELAGDRRVIDAYLGVGGKHQEMLAT"
     gene            2779..3246
                     /locus_tag="P5537_16720"
     CDS             2779..3246
                     /locus_tag="P5537_16720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF192 domain-containing protein"
                     /protein_id="HRV79732.1"
                     /translation="MKKRSSLLRASIFAVLCTAALSAAAQGVTARLPVAELGAGMYRI
                     EAEVAHTAEARQTGLMHRVAMPLQRGMVFVFAEDAVHCMWMRNTHLALSVAFIDAGGK
                     ILNIERMTPRTEDNHCAAAPARYALEMNAGWFEERGIAPGAVLRGIDRLPAAR"
BASE COUNT          466 a         1193 c         1231 g          573 t
ORIGIN      
        1 ccggtgctgg tgtggcgctc cctgaccagc caccacgtgg aggaagagga atgaagcccg
       61 cgctctcccc gcgcctggtg ctggccgcgt tcgccgcact gctggtcgtt gcgccgctgg
      121 cgctgccggc cttctacgtc accctgctca actacatcgg cctctacgcg atggtcgcgc
      181 tcgggctggt cctgctgacc ggtgtcggcg gcctgaccag cttcggccag gcggccttcg
      241 tcggcctggg ggcctacacc acggcgctgc tgaccacctc cgcggagctg cctggctggc
      301 tgtcctgggc cggcggctcg ccctggctgg ccctggtcgt cggcctgctg tttaccgtcg
      361 tggtcgcctt cctgatcggc aagctcacgt tgcgcctgtc cgggcactat ctgccgctgg
      421 ccaccatcgc ctggggcctg agcctgtatt tcctgttcgg caccatgggc ttcctcggcg
      481 gccataccgg cctcaccggc atcccgccga tctcgctgtt cggctacgag ctgcgccagg
      541 gcgaggaggt gtactacctg atctggctct tcgtgctcgc cggcgtgctg accaccagca
      601 acctgctcga ctcgcgcgag ggcagggcga tccgcgcgct caagggcggc atggtgatgg
      661 ccgaggcgat gggcgtcgac accgcacgct cgcgcatggt gatcttcatc ctcgccgcct
      721 tgctcgcctg tgcctcgggc tggctgtacg cgcacatgca gcgcttcgtg aacccgacgc
      781 cgttcggcct gcacatcggc atcgagtatc tgttcatggc ggtggtcggc ggtgcggcgc
      841 acgtctgggg cgcactcgtc ggcgcgggcg tgatcaccgt gctcaagcag tggctgcagg
      901 acctgctgcc ccagctcttc ggcaccagcg gcaacttcga ggtgatcttc ttcggggtgc
      961 tgatggtgct ggtgctgcac aaggcgcgcg gtgggctgtg gccgatcgtg gtgtccggct
     1021 tcaagcgctt cgtcccggtc gcggtacagc gccaggtcgt cgatcgtgat gcgcaggcgc
     1081 tgccgcggcg cgagctgccg gccgccggca gcctgctgct cgaggccaag gcggtgacgc
     1141 gccgcttcgg cggcctgctc gccaacaaca acatgagcct ggaggtgcgc gccggcgaga
     1201 tcctcgccct gatcggcccc aacggcgccg gcaagagcac gatgttcaac caggtctcgg
     1261 gcgtggatac gccgacctcg ggcgaggtcc tgttcctcgg cgagtcggtg gtcggcaagg
     1321 gctcgcgcac catcgcgcgc atgggcatga gccgcacctt ccagcacgtg cgcctgctgc
     1381 ccaccatgag cgtgctcgag aacgtcgcca tcggcgccca catgcggggc acgagcggcg
     1441 tgctgtcggc ggcgtggcgg atggaccgcg ccgaggaggc gcgcctgctc gccgaggctg
     1501 cgcgccagat cgagcgcgtc ggcctgggcg agcacatgtt cgacgaggcc ggcagcctcg
     1561 cgctcggtca gcagcgcatc ctcgagatcg cgcgcgccct cgcctccgac ccctgcctgc
     1621 tgctgctcga cgagccggcc gccggcttgc gctataagga gaaggaggcg ctcggcgacc
     1681 tgctgcgcaa gctgcgcggt gaaggcatgg gcgtgctgct ggtcgagcac gacatggact
     1741 tcgtgatggg cctggtcgat cgcgtggtgg tgatggagtt cggcgagaag atcgccgagg
     1801 gcctgccgga ggacgtgcag cgcgacccgg ccgtgctcgc ggcctacctc gggggagaag
     1861 actgatggcg acgaagaacc ttaccgatcg cccggtattg cgggtcgaag gcctgtgcgt
     1921 gtcctacggc aaggtcgagg cgctcaccga cgccagcatc acggtggggg agggccagat
     1981 cgtcaccgtg atcggcccca acggcgccgg caagaccacc atgctgtcgg cgatcatggg
     2041 gctgctgccc tcgcgtggcc gcatcgagtt cgacagcgtg gcgatggtgg cgccggaggt
     2101 cgagaccatg gttgcgagcg ggatgaacct ggtcccggag aagcgcgagc tgttcggcga
     2161 gatgagcgtc gaggacaacc tcgtgctcgg cgccttccag cgctaccgca tgggcttgcg
     2221 cgaccacgcc cagacgatgg aagagatcta cacgctcttc ccgcgcctgc gcgagcgccg
     2281 tacccagatg gcgggcaccc tctcgggcgg cgaacgccag atgctggcgg tcggacgtgc
     2341 gctgatggcc aagcccaagc tgctgatgct cgacgagccc agcctggggc tggcgccgct
     2401 gatcacgcgc gagatcttcc gcatcatcac ccagctgcgc agccgcgggg tgtccatcct
     2461 gctcgtagag cagaacgccc gcgcggcgct gcaggtggcg gactatgcct acgtgctcga
     2521 gaccggcggg gtcgccatgg agggccccgc ctccgagctc gccggcgacc gccgcgtgat
     2581 cgacgcctac ctcggcgtgg gcggcaagca tcaggagatg ctggcgacgt aaggattgag
     2641 gcgtgacgtg tgaggagcgg tgggggtggg gcgctcgtgg cctttccggc tgcgctggtt
     2701 tcgcgcctca cgcctaacgc cttcctcctc agcgcacgct aaactcgcgg cttcgacgct
     2761 tatcgggcct gctccgcgat gaagaaacgc tcctctctcc tccgcgcctc cattttcgcc
     2821 gtgctttgca ccgcagcctt gtccgccgct gcgcagggtg tcacggcccg cctcccggtc
     2881 gccgagctcg gggccgggat gtaccgcatc gaggccgagg tggcccacac cgccgaggcg
     2941 cgccagaccg ggctgatgca ccgcgtggcg atgccgctgc agcgcggcat ggtgttcgtg
     3001 ttcgccgagg acgcggtgca ctgcatgtgg atgcgcaaca cccacctggc gctgtcggtc
     3061 gccttcatcg acgccggcgg gaagatcctc aacatcgagc gcatgacgcc gcgcaccgag
     3121 gacaaccact gcgcggcggc gccggcgcgc tacgcgctcg agatgaacgc cggctggttc
     3181 gaggagcgcg ggatcgctcc gggcgcagtg ctgcgcggca tcgaccgcct gcccgcggcg
     3241 cgctgatggg cgcccgggcg ggtggagcgt ccgcccggga gtaggtcggc agcgcctcgg
     3301 tggcgccctc gcaaagcgca gaattgcagc cctttacggc gcgttctccg cgtccggccc
     3361 ttgtcggtgc cggcccataa tccgcatacg tcgtcgcgcg cccgcagtcc agcggcgcgg
     3421 cgcggcggcg gacggagccg gccgtggccg aagacagcga cct
//
LOCUS       DAOTIN010000210         3420 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_32751_length_3420_cov_6.476672, whole genome shotgun sequence.
ACCESSION   DAOTIN010000210 DAOTIN010000000
VERSION     DAOTIN010000210.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 3420)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3420)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3420
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_32751_length_3420_cov_6.476672"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(164..1216)
                     /locus_tag="P5537_16725"
     CDS             complement(164..1216)
                     /locus_tag="P5537_16725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011237278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HRV79733.1"
                     /translation="MGKLGSVPYFLLLLALVLLTGCSRGEVFHHEAYVFGTRVDVAVH
                     GDSQAEADAAAAAVLREFDRLHRAYHAWEPSELTALNESLARGEAATVSDELAAMLKD
                     AQHIAATGDQLFNPALGGLIALWGFHTDNVVPQRPDPAKLQALLDAAPSMADLVIDGN
                     RVSSRNPAVQLDLGGYAKGYALDRAATILRANGVANALINIGGNVMALGKKGDQPWRI
                     GIQHPRMPAPLATLPLYDGEAVGTSGDYQRYFELEGERYAHLLDPRTGQPARGTQSLT
                     ILITPREGAGPGAGTLSDAPSKPAYLVGEHWREHTRRFGIEHVLRVAADGRVEVTRAL
                     RARLQFPAPLEVTVVD"
     gene            complement(1270..2229)
                     /gene="gshB"
                     /locus_tag="P5537_16730"
     CDS             complement(1270..2229)
                     /gene="gshB"
                     /locus_tag="P5537_16730"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002931186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004363 - glutathione synthase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione synthase"
                     /protein_id="HRV79734.1"
                     /translation="MTRKLKLLFILDPLEGLKAYKDSSIAMMRAAARRGHEVWALQRA
                     GLTWREGVVIGTGCVALEVGADDAAWYRAGEAQALPLAAFDAVLMRQDPPFDFEYVTA
                     TWLLERAAQAGVRVFNDPRAVRDHSEKIAITEFPQFTATTLVARDPADIHAFIDELGD
                     VILKPLDGMGGSQIFRVRADDPNRNVIVETLAHEGTRTIMAQRYLPQIVDGDKRVLII
                     GGEVVPFSLARIPRAGETRGNLAAGGRGVAMALTVREREIAEYLAPILWSRGLLIVGL
                     DVIGGHLTEINVTSPTCMVEIAVQQGFDVAGLVIDKLERVCSR"
     gene            complement(2445..>3420)
                     /gene="gshA"
                     /locus_tag="P5537_16735"
     CDS             complement(2445..>3420)
                     /gene="gshA"
                     /locus_tag="P5537_16735"
                     /EC_number="6.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004323529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="glutamate--cysteine ligase"
                     /protein_id="HRV79735.1"
                     /translation="LQNVAKLVSILRFTGLDVRIGSLLPEIAEPTVLELANGATLTLE
                     PLRRSGSRIGLDDFDPCAVLLNNDLSAGIPQVLKGLDEQWLIPPLHAGWHKRRKSKHA
                     ECYDRVAREFAAAIGIDPWRINPEFGVCGQINFQERTGEECLAGQVDSLLTRIRAKYK
                     EYGVTDEPFVVVKADAGTYGMGVMTVKDASEVVGLNRRQRNKMAVVKEGLQVHEVIIQ
                     EGVHTFETVEDGVAEPVVYMMDHYVVGGFYRVHTERGRDENLNAPGMHFKPLAFDTSG
                     TMPDAAQGPDAPPNRFYAYGVVARLALLAASVEIEETAPAEDEDALAA"
BASE COUNT          494 a         1173 c         1212 g          541 t
ORIGIN      
        1 ccttcttgct gctcagctcg gcctcgagct cgtcgatgcg atccttggtg ccggccgtgc
       61 tgcggccgat gaagaacgcc accaccccca cgatgacgac ggcggaaatg gcgatcagcc
      121 aggcggtttg cggtgtcatg tccatgattc ccctcccttt ttttcaatcg acgaccgtca
      181 cctcgagcgg tgccgggaac tgcagccgcg cgcgcagcgc acgggtgacc tcgacgcgac
      241 catcggccgc gacgcgcaac acgtgttcga tgccgaaacg gcgagtatgt tcgcgccaat
      301 gctccccgac cagatacgcc ggcttgctcg gcgcgtccga caaggtgcct gcgccgggcc
      361 cagcgccctc gcgcggcgtg atcaggatgg tcagcgactg cgtgccgcgc gccggctggc
      421 cggtgcgcgg gtcgagcagg tgggcgtagc gttcgccctc gagctcgaaa tagcgctggt
      481 agtcgcccga ggtgcccacc gcctcgccgt cgtagagcgg cagcgtggcg agcggcgccg
      541 gcatgcgcgg gtgctggatg ccgatgcgcc acggctggtc gcccttcttg ccgagcgcca
      601 tgacgttgcc gccgatgttg atcagcgcgt tggccacgcc gttcgcgcgc aggatggtgg
      661 cggcgcggtc gagcgcgtag cccttggcat agccgccgag atcgagctgc accgccggat
      721 tgcggctgct cacccggttg ccgtcgatga cgaggtcggc catcgacggc gcggcgtcga
      781 gcagggcctg cagcttggcc gggtcggggc gctgcggcac gacgttgtcg gtatgaaaac
      841 cccacagcgc gatcaggccg ccgagcgcgg ggttgaagag ctgatcgccg gtggcggcga
      901 tgtgctgggc gtccttgagc atagccgcca gttcgtccga cacggtggcg gcctcaccgc
      961 gtgcaaggga ttcgttgagc gcggtgagct cggagggctc ccaggcgtgg taggcgcgat
     1021 gcaggcggtc gaactcgcgc agcaccgccg cagccgccgc atcggcctcg gcctggctgt
     1081 cgccatgcac ggcgacatcg acacgggtgc cgaagacata ggcctcgtgg tggaagacct
     1141 ccccgcgcga acagccggtg agcagcacca gcgccagcag caacaggaaa taggggacag
     1201 accccaattt ccccatggaa attggggtct gtcccctatt tccatttccc ggaaccgctg
     1261 cggcagcact catcggctac agacccgctc cagcttgtcg atcaccaggc cggccacatc
     1321 gaagccctgc tgcacggcga tctcgaccat gcaggtgggg ctggtgacgt tgatctcggt
     1381 gaggtggccg ccgatcacgt ccaggccgac gatcagcagc ccgcgcgacc acaggatggg
     1441 cgccaggtat tcggcgatct cgcgctcgcg cacggtgagc gccatcgcca ccccgcgccc
     1501 gccggcggcg aggttgccgc gcgtctcgcc cgcccgcggg atgcgcgcga gcgagaacgg
     1561 cacgacctcg ccgccgatga tcagcacgcg cttgtcgccg tcgacgatct ggggaaggta
     1621 gcgctgcgcc atgatggtgc gcgtgccctc gtgggcgagc gtctccacga tcacgttgcg
     1681 gttggggtcg tcggcgcgca cgcggaagat ctggctgccg cccatgccgt cgagcggctt
     1741 gaggatgacg tcgccgagct cgtcgatgaa ggcgtggatg tcggccggat cgcgcgccac
     1801 cagcgtggtc gcggtgaact gcgggaactc ggtgatggcg atcttctcgg agtggtcgcg
     1861 caccgcgcgc gggtcgttga acacgcgcac gccagcctgc gcggcgcgct cgagcagcca
     1921 ggtggcggtg acgtactcga agtcgaaggg cgggtcctgg cgcatcagca ccgcgtcgaa
     1981 ggcggccagc ggcagggcct gcgcctcgcc ggcgcgatac caggccgcgt cgtcggcgcc
     2041 gacctcgagc gccacgcagc cggtgccgat caccacgccc tcgcgccagg tgaggccggc
     2101 gcgctgcagc gcccacacct cgtgtccgcg ccgcgcggcg gcacgcatca tcgcgatgct
     2161 ggaatccttg taggccttga ggccctcgag cgggtcgagg atgaagagga gcttgagctt
     2221 gcgggtcatg acttgatcac acgttccatt gactgcccgt ctccgggctg cagatgcggc
     2281 aagcgccgcg agccactgcg caacagccgc cccggcccct gtgcgaccac cggctcgccc
     2341 cctgcaggag cggcgggagc cgcgagcctt tcggcctggg tccagtcggc cgcatcgcct
     2401 tcagcccctc gcggctcgcg ccgcgcctgc ggggccggac aagctcatgc ggccagcgcg
     2461 tcctcgtcct ctgcgggcgc ggtctcctcg atctcgaccg aggccgcgag cagcgccagg
     2521 cgcgcgacca cgccataggc gtagaaacgg ttcggcggcg cgtccgggcc ctgggcagca
     2581 tcgggcatgg tgccgctggt gtcgaaggcc agcggcttga agtgcatgcc cggcgcgttg
     2641 aggttctcgt cgcggccgcg ctcggtgtgg acgcggtaga agccgcccac cacgtagtgg
     2701 tccatcatgt agacgaccgg ctcggcgacg ccgtcctcga ccgtctcgaa ggtgtgcacg
     2761 ccctcctgga tgatgacctc gtgcacctgc aggccttcct tgaccaccgc catcttgttg
     2821 cgctggcggc ggttgaggcc gaccacctcg gaggcgtcct tcaccgtcat cacgcccatg
     2881 ccgtaggtgc cggcgtcggc cttgaccacc acgaagggct cgtcggtgac gccgtactcc
     2941 ttgtacttgg cgcggatgcg ggtgagcagc gaatccacct ggccggccag gcactcctcg
     3001 ccggtgcgct cctggaagtt gatctggccg cacacgccga actcggggtt gatgcgccac
     3061 gggtcgatgc cgatcgccgc ggcgaactcg cgcgcgacgc ggtcgtagca ctcggcgtgc
     3121 ttcgacttgc ggcgcttgtg ccagcccgcg tgcagcggcg ggatcagcca ctgttcgtcg
     3181 aggcccttga gcacctgcgg gatgccggcg gagaggtcgt tgttgagcag caccgcgcac
     3241 gggtcgaagt cgtccaggcc gatgcggctg ccgctgcggc gcagcggctc cagcgtcagc
     3301 gtggcgccgt tggcgagttc cagcacggtg ggctcggcga tctcgggcag caggctgccg
     3361 atgcgcacgt ccaggccggt gaagcgcagg atggacacca gcttggccac gttctgcagg
//
LOCUS       DAOTIN010000211         3408 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_32893_length_3408_cov_10.791530, whole genome shotgun
            sequence.
ACCESSION   DAOTIN010000211 DAOTIN010000000
VERSION     DAOTIN010000211.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 3408)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3408)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3408
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_32893_length_3408_cov_10.791530"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..213)
                     /locus_tag="P5537_16740"
     CDS             complement(<1..213)
                     /locus_tag="P5537_16740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia channel protein"
                     /protein_id="HRV79736.1"
                     /translation="MRKLFALLPAAALLAGASGGAFAQEAAAAAAEVHKGDVAWIMTS
                     TLLVLMMALPGLALFYGGMVRKKNVLA"
     gene            complement(228..566)
                     /gene="glnK"
                     /locus_tag="P5537_16745"
     CDS             complement(228..566)
                     /gene="glnK"
                     /locus_tag="P5537_16745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_253975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030234 - enzyme regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HRV79737.1"
                     /translation="MKFIAAIIKPFKLDEVREALSAIGVQGITVTEVKGFGRQKGHTE
                     LYRGAEYVVDFLPKVKVEAAIPDDILDQAIEAIEKSAATGKIGDGKIFVFELEQAIRI
                     RTGETGPEAL"
     gene            complement(595..1299)
                     /locus_tag="P5537_16750"
     CDS             complement(595..1299)
                     /locus_tag="P5537_16750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TorF family putative porin"
                     /protein_id="HRV79738.1"
                     /translation="MRTKPLATALAALATIAAAGAAHAGDGPFTANVGLVSDYAYRGS
                     SQTDERPALQGGFDYAHDSGLYAGVWGSNVSWLSDSNPNVHNSLELDIYGGYKGTIGA
                     IGYDVGLLQYYYPGSYPKGFNSPNTLEGYVGLSWEFLSFKYSYAFTDLFGYDKSDGSQ
                     YYDLGAAVDVGGGFTLAAHVGYSDIKGQDDYTDWKLGVTKEFGGFNFGLHYVDTDVNN
                     ADLADERVILSIAKSF"
     gene            1606..1857
                     /locus_tag="P5537_16755"
     CDS             1606..1857
                     /locus_tag="P5537_16755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004381043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory factor UbiK family protein"
                     /protein_id="HRV79739.1"
                     /translation="MSTPRILDEIGARLSELAANSPVRDIEKNAKAMLGSAFGKLDLV
                     TREEFEVQREVLAQARRKLAELEARVAELEAKLTGGDKA"
     assembly_gap    1897..1996
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            2331..>3408
                     /locus_tag="P5537_16760"
     CDS             2331..>3408
                     /locus_tag="P5537_16760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011767458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HRV79740.1"
                     /translation="MSLALVHARALDGIEAPPVTVEVHLGNGLPQFHLVGLADTEVRE
                     ARDRVRAAIQSAQFEFPQRRITVNLAPADLPKEGGRFDLAIAIGILAASGQVAERQLA
                     RLELCGELSLNGGLRPVRGVLAAALAAARAGRALVLAPANAAEAALARSATVLPADSL
                     GAVCAHLNGHTRLEPAAAPDPEGEVGAALPDLADVRGQLQARRALEVAAAGGHSLLLF
                     GPPGTGKSMLAQRLPGVLPAMDEDEAIEAAAVASIEGRFDPQGFHRRPFRAPHHSASA
                     AALVGGGAVPRPGEISLAHHGVLFLDELPEFDRRVLESLREPLETGTVTVSRARRRAE
                     FPARFQLVAAMNPCPCGHLGDPRRA"
BASE COUNT          427 a         1135 c         1194 g          552 t
ORIGIN      
        1 ggccagcacg ttcttcttgc gcaccatgcc gccgtagaac agcgccaggc cgggcagggc
       61 catcatcagc acgagcagcg tcgaggtcat gatccaggcc acgtcgccct tgtgcacctc
      121 ggccgcggcg gctgcggcct cctgggcgaa ggcgccgccc gacgcgccgg cgagcagggc
      181 tgccgccggc aggagtgcga agagttttct cattttgcgt tgctccctta cagcgcttcc
      241 gggccggtct cgccggtgcg gatgcggatg gcctgctcga gttcgaagac gaagatcttg
      301 ccgtcgccga tcttgccggt ggcggcggac ttctcgatcg cctcgatcgc ctggtcgagg
      361 atgtcgtcgg ggatggcggc ctcgaccttg accttgggca ggaagtcgac gacgtactcg
      421 gcgccgcggt agagctcggt gtggcccttc tggcggccga agcccttgac ctcggtgacg
      481 gtgatgccct gcacgccgat ggccgagagc gcctcgcgga cctcgtcgag cttgaagggc
      541 ttgatgattg cggcgatgaa tttcatgtct ttctccggtt ccagggggcg gtgatcagaa
      601 gctcttggcg atcgacagga tcacgcgctc gtcggcgagg tccgcgttgt tcacatcggt
      661 gtcgacgtag tgcaggccga agttgaagcc gccgaactcc ttggtgacgc ccagcttcca
      721 gtcggtgtag tcgtcctggc ccttgatgtc gctgtagccg acgtgggcgg cgagggtgaa
      781 gccgccgccg acatcgaccg cggcgccgag gtcgtagtac tggctgccgt cggacttgtc
      841 gtagccgaac aggtcggtga aggcgtagga gtacttgaag gagaggaact cccacgacag
      901 gccgacgtag ccctcgagcg tgttcgggct gttgaagccc ttggggtagc tgcccgggta
      961 gtagtactgc agcaggccga cgtcgtagcc gatggcgccg atcgtgccct tgtagccgcc
     1021 gtagatgtcg agctcgaggc tgttgtggac gttcgggttg ctgtcggaca gccacgacac
     1081 gttcgagccc cacacgccgg catagaggcc actgtcgtgg gcgtagtcga agccgccctg
     1141 cagcgcgggg cgctcgtcgg tctggctcga gccgcggtag gcgtagtcgg acaccaggcc
     1201 gacgttggcg gtgaaggggc cgtcgccggc gtgggcggcg ccggcggcgg cgatcgtggc
     1261 gagggcggcg agcgcggtgg cgagcggttt cgtgcgcatg gtcatctcct gacgagggtt
     1321 tcgaagttcg cgacgagact ccctaagcat ggggcgtgcc agggcgcgga aagccagtga
     1381 attcgtggtt ctcggctcgt agcccggccg gtcttgctgc gctgcggcag gggttggcgc
     1441 gcgatttcgg ggcgctgcgc accaatctgg tgcgtctgat gcggcgcgga gtgccgggcg
     1501 cgtcgtgtct ttcgcgagcg cgtcgctccg ggtccgctgc cctccggcga gcaggggcct
     1561 gcgtgctaga cttcgacgcc tctgcaatcc ggaatccacg ccatcatgag cacgccccgc
     1621 atcctcgacg aaatcggcgc acgcctctcc gaactcgccg ccaacagccc cgtccgcgac
     1681 atcgagaaga acgccaaggc catgctcggc tcggccttcg gcaagctcga cctcgtcacc
     1741 cgcgaggaat tcgaggtgca gcgcgaggtc ctcgcgcagg cgcggcgcaa gctcgccgag
     1801 ctcgaggcgc gcgtcgccga gctggaagcc aagctgaccg gcggcgacaa ggcctgatcc
     1861 tggcgcggcc tcatgcgccg cattcgcgcc tgccggnnnn nnnnnnnnnn nnnnnnnnnn
     1921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1981 nnnnnnnnnn nnnnnncggc gacaaggcct gatcctggcg cggcctcatg cgccgcattc
     2041 gcgcctgccg gcgctcctac agggctttcg ggggctcgcc ggtttccgcg ttcgcgcctg
     2101 ccggcgctcc tacaaggttt tcgggggctc gccggtttct gtaggagcgg cggcagccgc
     2161 gaacaaggcg gcgacgggcg ctgtggcttt cgacatgctg cgttcggtcc cgcatgaaac
     2221 accgtatgcg gctcgcggcc gagcgctcct cgatcgcgcg cttcgcataa ttctttgtca
     2281 tcgatcgagg ctccgctaga ctgacggctc cttttccccc ggagtcgccg atgtcgctcg
     2341 ccctcgtgca tgcacgcgcg ctcgacggga tcgaggcgcc gccggtcacg gtcgaagtcc
     2401 atctcggcaa cggcctgccc cagttccacc tcgtcggcct cgccgacacc gaagtgcgcg
     2461 aggcgcgcga ccgcgtgcgt gcggcgatcc agtcggcgca gttcgagttt ccccagcgcc
     2521 gcatcaccgt caacctggca ccggccgacc tgcccaagga gggcgggcgc ttcgacctgg
     2581 cgatcgcgat cggcattctc gccgcctcgg gccaggtggc cgagcggcag ctcgcgcgcc
     2641 tggagctgtg cggcgagctc tcgctgaacg gcggtctgcg cccggtgcgc ggggtgctcg
     2701 ccgcagcgct tgccgccgcg cgagccgggc gcgcgctggt gctggcgccc gccaatgccg
     2761 ccgaggccgc gctggcgcgc agcgccacgg tgctgccggc cgacagcctc ggcgcggtgt
     2821 gcgcgcatct caacggacac acccgcctcg aacccgcggc ggcccccgat ccggagggcg
     2881 aggtcggcgc tgcgctgccc gatctcgccg acgtgcgcgg ccagctgcag gcgcggcgcg
     2941 cgctcgaggt cgccgcggcg ggcgggcact cgctgctgct gttcgggccg ccgggcacgg
     3001 gcaagtcgat gctggcgcag cgcctgccgg gcgtgctgcc ggcgatggac gaggacgagg
     3061 cgatcgaggc cgccgcggtg gcctcgatcg aggggcgctt cgatccgcag ggcttccacc
     3121 gccggccgtt ccgcgcgccg caccactcgg cctcggcggc ggcgctggtg ggcggcggcg
     3181 cggtgccgcg cccgggcgag atctcgctcg cgcaccatgg cgtgctgttc ctcgacgagt
     3241 tgcccgagtt cgaccgccgc gtgctcgagt ccctgcgcga gccgctcgag accggcaccg
     3301 tcacggtgtc gcgtgcgcgc cggcgcgcgg agttccctgc ccgcttccag ctcgtcgccg
     3361 cgatgaaccc ctgtccctgc ggccacctcg gtgacccgcg ccgtgcct
//
LOCUS       DAOTIN010000212         3342 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_33750_length_3342_cov_9.056282, whole genome shotgun sequence.
ACCESSION   DAOTIN010000212 DAOTIN010000000
VERSION     DAOTIN010000212.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 3342)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3342)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3342
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_33750_length_3342_cov_9.056282"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1289)
                     /locus_tag="P5537_16765"
     CDS             complement(<1..1289)
                     /locus_tag="P5537_16765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004319523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HRV79741.1"
                     /translation="MSDPPMNERHILIVDDEELYRELLGGRLGRQGYRISEAGDGEGA
                     LRCIEGGGVELALIDIKMPGMDGIELLERIKQLAPRTEVVVLTGHGSIDSAIAAMKLG
                     AFDYLTKPYQLTELDLVVARALERSALARRCDALSLEVERLRRRDDDGLVGESPAWLQ
                     MLEQVRRAAALDVPVLLTGESGAGKEVVAAALHRWSRRAGEAYVPVNCGLLEGELVES
                     ELFGHKRGAFTGASADREGLFELASAGTLFLDEIGELPLACQAKLLRVLDSGEFRPLG
                     ASAVRRTGARVIAATHRDLEALVGAGRFRHDLLYRLDVVHIVVPPLRERHEDIPLLVE
                     HLLHQAVRRHPGTPAPRVEAQALQRLIEHPWPGNVRELRNVVERLLVFADGERIDAAR
                     IDALLHPGATTTASTGRSGFERIVPLAEMEQAYLRWVV"
     gene            complement(1282..>3342)
                     /locus_tag="P5537_16770"
     CDS             complement(1282..>3342)
                     /locus_tag="P5537_16770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HRV79742.1"
                     /translation="ILVHADSMGALRKELVETLGSEIAKVVLTRYGFSCGYEDAELLA
                     AYMHPDSLEEFILGGPRTHMFSGIAVVEPDALELDAANGRYRMSGRWRHSYEAEQHLR
                     LFGRADEPVCWTLTGYASGFASRVLEADMICVETACEGRGDPHCAWTLMNASDCAPEL
                     AGLREYFKPLNLRDRLNLLESRVHERTRELEASEQRYRNLIEDLPEMAFALHASGRLL
                     HLNKAARARLGVSEAQLPALRLKDLVLPDYTARATAFLKEIAARRSTTTLDLVMRDAA
                     GLPFPVRLQVEPVLKDDRIVGYSGLALDISAQLERERELTEYARRIESREQQIQDVIN
                     EAVYILDGQGRLSFVNTRMAELLGATPEAAIGHAVGDFMPAASAARIERDFARRIAGE
                     AGRPFEIALAGRDGGSVVLEVNSTLFVGRDVAEGVIGVARDITARRRMERELAQANRL
                     SALGQFASGVAHEINNPLGLVSGYAEELQALLDEGAPHGDDPRFARLRRGLATIQQQA
                     HRCKAITANLLAFSRRQSASLETVDVGLFVAERLAFFNEAGLTRGVELAVDIAPGLPQ
                     AGTSPALLEQVLQNLIKNACDAMNGSGRIDIAARAGSEGIVIEIGDSGPGFAPGVAEH
                     VFDPFFTTKPPGKGTGLGLSICYAIMNELGGRIACGNRPQGGAWFRLVLPLAEDGAGA
                     ARDE"
BASE COUNT          433 a         1176 c         1244 g          489 t
ORIGIN      
        1 accacccagc gcaggtaggc ctgctccatc tcggcgagcg ggacgatgcg ctcgaagccg
       61 ctccggccgg tgctcgcggt cgtcgtcgcg cccgggtgca gcaaggcgtc gatgcgggcc
      121 gcgtcgatgc gctcgccgtc ggcgaagacc agcaggcgct cgaccacgtt gcgcagctcg
      181 cgcacgttgc ccggccaggg atgctcgatc aggcgttgca gggcctgggc ctcgacgcgc
      241 ggcgctggcg tgccggggtg gcgccgcacc gcctggtgca gcaggtgctc gaccagtagc
      301 gggatgtcct cgtggcgctc gcgcagcggc ggcacgacga tatggaccac gtcgagccgg
      361 tacagcaggt cgtggcggaa gcggcccgcg cccacgaggg cctcgaggtc gcggtgggtg
      421 gcggcgatca cgcgcgcgcc ggtgcggcgc acggcgctgg cgccgagcgg gcggaactcg
      481 ccgctgtcga gcacgcgcag cagcttggcc tggcaggcga gcggcagctc gccgatctcg
      541 tcgaggaaga gggtgccggc gctcgccagc tcgaagaggc cctcgcggtc cgcgctcgca
      601 ccggtgaagg cgccgcgctt gtggccgaag agctcgctct cgaccagctc gccctcgagc
      661 aggccgcagt tcaccggtac ataggcctcg cccgcgcgcc ggctccagcg gtgcagcgcg
      721 gcggccacca cctccttgcc ggcgccgctt tcgccggtga gcagcaccgg cacgtcgagc
      781 gcggccgcgc ggcgcacctg ctcgagcatc tgcagccaag ccgggctttc tcctaccagg
      841 ccgtcgtcgt cgcgcctgcg caggcgctcc acctccagcg agagcgcgtc gcagcggcgc
      901 gcgagcgcgc tgcgttcgag cgcgcgcgcg accacgaggt cgagctcggt gagctggtag
      961 ggcttggtga ggtagtcgaa ggcgcccagc ttcatcgccg cgatcgcgct gtcgatgctg
     1021 ccgtggccgg tcagcaccac gacctcggtg cgcggcgcga gctgcttgat gcgctcgagc
     1081 agctcgatgc cgtccatgcc cggcatcttg atgtcgatga gggcgagctc cacgccgccg
     1141 ccctcgatgc agcgcagcgc gccctcgccg tcgccggcct cgctgatgcg gtagccctgg
     1201 cggccgaggc ggccgccgag cagctcgcgg tagagctcct cgtcgtcgac gatcaggatg
     1261 tggcgttcgt tcatgggtgg atcactcatc cctcgccgct cccgctccgt cctccgccag
     1321 cggcagcacc aggcggaacc acgcgccgcc ctgcggccgg ttgccacagg cgatgcggcc
     1381 gcccagctcg ttcatgatcg cgtagcagat cgacaggccc agcccggtgc ccttgcccgg
     1441 cggcttggtg gtgaagaagg ggtcgaagac gtgctcggcg accccgggcg cgaagcccgg
     1501 cccgctgtcg ccgatctcga tcacgatgcc ctcgctgccg gcgcgcgcgg cgatgtcgat
     1561 gcgcccgctg ccgttcatcg cgtcgcaggc gttcttgatc aggttctgca gcacctgttc
     1621 gagcagggcc gggctggtgc cggcctgcgg caggccgggc gcgatgtcga ccgcgagctc
     1681 gacgccgcgg gtgaggccgg cctcgttgaa gaaggccagg cgctcggcga cgaagaggcc
     1741 cacgtccacc gtctccaggc tggcgctctg gcggcgcgag aaggcgagca ggttggcggt
     1801 gatcgccttg cagcggtggg cctgctgctg gatggtggcg agcccgcggc gcagccgcgc
     1861 gaagcgtggg tcgtcgccgt gcggtgcgcc ttcgtcgagc agggcctgga gctcctcggc
     1921 gtagcccgac accaggccga gcgggttgtt gatctcgtgc gccacgcccg aggcgaactg
     1981 gccgagcgcg ctcagccggt tggcctgtgc gagctcgcgc tccatccgcc ggcgtgcggt
     2041 gatgtcgcgc gccacgccga tcacgccctc ggcgacgtcg cggccgacga agagggtgga
     2101 gttgacctcc agcaccacgc tgccgccgtc gcgtccggcg agcgcgatct cgaagggccg
     2161 gccggcctcg ccggcgatgc ggcgggcgaa gtcgcgctcg atgcgtgcgg ccgacgcggc
     2221 cggcatgaaa tcgcccaccg cgtgcccgat cgccgcctcg ggcgtggcgc cgagcagctc
     2281 ggccatgcgg gtgttgacga agctcagccg gccctggccg tcgaggatgt agaccgcctc
     2341 gttgatcacg tcctggatct gctgttcgcg ggactcgatg cggcgcgcgt actcggtgag
     2401 ctcgcgctcg cgctcgagct gggcgctgat gtcgagcgcc agcccgctgt agcccacgat
     2461 gcgatcgtcc ttgagcaccg gctcgacctg cagccgcacc gggaagggca ggccggcggc
     2521 gtcgcgcatc accaggtcga gcgtggtggt gctgcggcgc gcggcgatct ccttgaggaa
     2581 ggcggtggcg cgcgcggtgt agtcggggag cacgaggtcc ttgaggcgca gcgcggggag
     2641 ctgcgcctcg ctcaccccca ggcgcgcgcg cgccgccttg ttcaggtgca gcaggcgccc
     2701 cgaggcgtgc agcgcgaacg ccatttcggg gaggtcctcg atgaggttgc ggtagcgctg
     2761 ctccgaggcc tccagctcgc gggtgcgctc gtgcacccgg ctctcgagca ggttgaggcg
     2821 gtcgcgcagg ttgagcggct tgaagtattc gcgcaggccg gcgagctcgg gcgcacagtc
     2881 gctggcgttc atcagcgtcc acgcgcagtg ggggtcaccg cgcccctcgc aggccgtctc
     2941 cacgcagatc atgtcggcct ccagcacgcg cgaggcgaaa cccgaggcgt agccggtcag
     3001 cgtccagcac accggctcgt cggcgcggcc gaacaggcgc aggtgctgct cggcctcgta
     3061 ggaatgccgc cagcgcccgc tcatgcggta gcgcccgttt gcagcgtcga gctcgagcgc
     3121 atcgggctcg accacggcga tgcccgagaa catgtgggtg cgcggtccgc cgaggatgaa
     3181 ctcctccagg ctgtccgggt gcatgtaggc ggcgagcagc tcggcgtcct cgtagccgca
     3241 actgaagccg tagcgggtga gcaccacctt ggcgatctcg ctgcccaggg tctcgaccag
     3301 ctccttgcgc agcgcgccca tcgagtcggc atggacgagg at
//
LOCUS       DAOTIN010000213         3182 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_35950_length_3182_cov_9.855453, whole genome shotgun sequence.
ACCESSION   DAOTIN010000213 DAOTIN010000000
VERSION     DAOTIN010000213.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 3182)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3182)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3182
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_35950_length_3182_cov_9.855453"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..469)
                     /locus_tag="P5537_16775"
     CDS             complement(<1..469)
                     /locus_tag="P5537_16775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LUD domain-containing protein"
                     /protein_id="HRV79743.1"
                     /translation="MQEATLSFKARAKEALADPTLKIAIDRTTGTAERKRAVAMTQFP
                     QFEAARERGKRIKDHVIANLDHYLLEFERNAIASGAKVHWARTAEEASQIVVRLCKEA
                     GAKRVTRVKSMLGEEIGLPHALDEAGIERVETDLAEHIVQLGGDRPSHIVWPSM"
     gene            complement(473..1264)
                     /locus_tag="P5537_16780"
     CDS             complement(473..1264)
                     /locus_tag="P5537_16780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(Fe-S)-binding protein"
                     /protein_id="HRV79744.1"
                     /translation="MTTTLKQIGAFSSPPRVGLFVTCLVDAMRPSVGFATLKLLRDAG
                     CRVEVPDAQTCCGQPAFNSGDTADAAVLARHFIETFEGYDYVVAPSGSCVGMTRAHYA
                     EALADDPAWAERARRLGERTYELMSFLVDVMHFAPADVKLDTSFTYHDSCSGLRELGV
                     HDQPRALLGKVSGLTLKPLEGNDVCCGFGGTFCVKYPAISNAVVGEKADAIDRSGASL
                     LLGGDLGCLMNMAGKLKRKGSSVRSFHAAEVLAGMAGGPAIGEER"
     gene            complement(1408..3108)
                     /locus_tag="P5537_16785"
     CDS             complement(1408..3108)
                     /locus_tag="P5537_16785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004358288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate permease"
                     /protein_id="HRV79745.1"
                     /translation="MTLGLQALLAFIPIGLSGLLLIGLGWSAKRAMPLVYFVTAAIAL
                     LAWGVSLNRIAAATLEGLIITVQVLWIIFGALLLLNTLKHSGGIASIRSGFARISPDR
                     RVQVILIAWLFGSFIEGASGFGTPAAVAGPLMVAVGFPALSAVMFGMIIQSTPVSFGA
                     VGTPLIVGVQGGLQREAMTAALQAQGQDWTAFFSLIVERVSLGHAICGTLIPVFLVMF
                     MTRFFGRNKSWAEALPIVPFALFSAFAFTVPYALAGRFLGPEFPSLLGGLLGLTVVSL
                     AARAGFLVPKKSWDFAEPKEWPAEWMGTFEMKIDQNTRKIPIFVAWLPYLLLALVLVL
                     SRTVAPFKQALLSVSWSVRDILGEPGISGNFQPLYLPGGVLVAVCLVTIILHKMYLPS
                     FGRAVKESSTTLLSAGFVLVFTVPMVRIMIQSGVNANEFASMPISMALWVASAVGDIY
                     PIFAPTVGALGAFLAGSNTVSNLMLSQYQYSVAQALGVSGATMVAAQSIGAAAGNMIA
                     IHNVVAASATVGVMGREGQILRRTIIPTIYYVALAGILAMLSMHVLNLGDPLLGVKLP
                     "
BASE COUNT          599 a         1025 c         1042 g          516 t
ORIGIN      
        1 gcatcgacgg ccacacgatg tgcgaggggc ggtcgccgcc gagctgcacg atgtgttcgg
       61 cgaggtcggt ctcgacgcgc tcgatgccgg cttcgtcgag cgcatgcggc aggccaattt
      121 cttcgccgag catcgacttg acgcgggtga cacgcttggc gccggcttcc ttgcacagac
      181 gcacgacgat ctgcgaggcc tcttccgccg tcctcgccca gtgcaccttg gcgccggagg
      241 cgatcgcgtt gcgctcgaac tcgagcaggt aatggtcgag gttcgcgatg acgtggtcct
      301 tgatgcgctt gccgcgctcg cgagcggcct cgaactgcgg gaactgcgtc atcgccaccg
      361 cgcgcttgcg ctcggccgtg ccggtggtgc gatcgatcgc gatcttgagc gtcgggtccg
      421 ccagtgcttc cttggcgcgc gccttgaagg agagggttgc ttcctgcatg gctcagcgct
      481 cctcgccgat ggccggaccg ccggccatgc cggccagcac ctcggcggcg tggaagctgc
      541 gcacgctcga gcccttgcgc ttgagcttgc cggccatgtt catcaggcag ccgaggtcgc
      601 caccgagcag caggctcgcg ccgctgcggt cgatggcgtc ggccttctcg ccgacgaccg
      661 cgttcgagat cgccggatac ttgacgcaga aggtgccgcc gaaaccgcag cacacatcgt
      721 tgccctccag cggcttcagc gtgagcccgg acaccttgcc cagcagggcg cgcggctggt
      781 catggacgcc gagctcgcgc aggccggagc aactgtcgtg gtaggtgaag ctggtgtcga
      841 gcttcacatc ggcgggcgca aagtgcatca cgtccaccag gaagctcatg agttcgtaag
      901 tgcgttcgcc gagccggcgg gcgcgttctg cccaggcggg atcgtccgcc agggcctcgg
      961 catagtgcgc ccgcgtcatg ccgacacagg aaccggaggg cgcgacgacg tagtcgtagc
     1021 cctcgaaggt ctcgatgaaa tggcgggcga gcaccgccgc gtcggcggtg tcaccgctgt
     1081 tgaaagccgg ctggccgcag caggtctgcg cgtccggtac ctcgacacgg catccggcat
     1141 cgcgcagcag cttgagcgtg gcgaagccga cgctggggcg catcgcatcg accaggcagg
     1201 tgacgaagag gccgacacgc ggtggcgacg agaaggcacc tatctgtttg agggtagtgg
     1261 tcatagtcgt acgctccata cattcgatca gaacccagcg cagtcgtgac gccctgcccg
     1321 cgctgggctc ttgccgacaa agcgcgatca cacagctacg gtcaatattg ccgagttcgg
     1381 gtaatagtgc ttacaacggt cagttactca cggcaatttc acgcccagca aggggtcgcc
     1441 caagttcaat acatgcatag acagcatcgc cagtattccg gcaagagcca cgtagtagat
     1501 cgtcgggatg atggtgcgcc gcaggatctg cccctcgcgc cccatgaccc ccacggtcgc
     1561 cgacgcggcc accacgttgt ggatcgcgat catgttgccc gccgccgctc cgatggactg
     1621 cgctgcgacc attgttgcgc cgctgacgcc cagtgcctgc gcaacgctgt actggtactg
     1681 gctcagcatc aggttcgaca cagtgttcga accggcaaga aaggccccga gagcgccgac
     1741 cgtcggggcg aatatcgggt agatgtcccc gaccgctgat gccacccaga gtgccatcga
     1801 gatcggcatg ctcgcgaact cgttcgcgtt cacgccggac tggatcatga tgcggaccat
     1861 cggcacggtg aacaccagta cgaagccggc gctcagcagc gtggtggagg attccttgac
     1921 cgccctcccg aaggaaggga ggtacatctt gtgcaaaatg atcgtcacca agcacacggc
     1981 gaccagtacg ccgccgggga ggtacagggg ctggaaattg ccgctgatgc ccggctcgcc
     2041 gaggatgtcg cgtacgctcc aactcaccga cagcagcgct tgcttaaagg gtgccaccgt
     2101 gcggctgagc accagcacca gggcaagcaa caggtaaggc agccaggcga cgaagatggg
     2161 gattttcctc gtgttctggt cgatcttcat ttcgaaggtg cccatccatt cggccggcca
     2221 ctccttcggc tcggcgaagt cccaactctt cttcggcacc aggaacccgg cccgcgccgc
     2281 gagggatacc acggtaaggc cgagcagacc gccgagcaag gacgggaact caggcccgag
     2341 aaagcggccg gccagggcat acgggacggt gaaggcgaat gcggagaaga gcgcgaacgg
     2401 cacgatcggc aaggcctcgg cccacgactt gttgcgaccg aagaatcgcg tcatgaacat
     2461 taccaagaac acggggatca gcgtgccgca gatggcatgg cccaaggaga cgcgctcgac
     2521 gatcagactg aagaaggccg tccagtcctg cccctgcgcc tgcagtgccg cggtcatcgc
     2581 ctcgcgctga aggccgccct gcacgccgac gatcaatggc gtaccgacgg cgccgaagga
     2641 gaccggcgtc gactggatga tcatcccgaa catcaccgcc gacagcgccg gaaagccgac
     2701 cgccaccatc agcgggccgg ccacggcggc cggtgtcccg aagccggacg caccctcgat
     2761 gaacgatccg aacaaccacg cgatgaggat gacctgcacg cgtcgatcag gactgatgcg
     2821 cgcgaacccg ctgcggatgc tggcgatgcc gcccgagtgc ttcagggtgt tcagcagcag
     2881 cagcgcgccg aagatgatcc atagcacctg gaccgtgatg atcagcccct cgagcgtggc
     2941 cgccgcgata cggttgaggc tcacgcccca ggcgagcaac gcgatcgccg cggtcacgaa
     3001 gtagaccagg ggcatggcac gcttggccga ccacccgagt ccgatgagaa ggaggccgga
     3061 gaggcctatc ggtatgaatg ccaacagtgc ttgcaggccg agcgtcatga tttgtctccc
     3121 ttcgcaattt ctttgagttg ttgtgtatcg gtcgtccgga tcggcgtgcg cagggcgacg
     3181 at
//
LOCUS       DAOTIN010000214         3047 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_38064_length_3047_cov_8.366310, whole genome shotgun sequence.
ACCESSION   DAOTIN010000214 DAOTIN010000000
VERSION     DAOTIN010000214.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 3047)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3047)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3047
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_38064_length_3047_cov_8.366310"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..177
                     /locus_tag="P5537_16790"
     CDS             <1..177
                     /locus_tag="P5537_16790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HRV79746.1"
                     /translation="IHAGKLCGDVDFESAKEVAGAITPVPGGVGPMTITMLLENTVIS
                     AERAASDRKLAAGK"
     gene            188..679
                     /gene="purE"
                     /locus_tag="P5537_16795"
     CDS             188..679
                     /gene="purE"
                     /locus_tag="P5537_16795"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HRV79747.1"
                     /translation="MSETQPVVGIIMGSNSDWPTMKAAAKMLEDFGVPFEARVVSAHR
                     TPDLMFDYAEAARGRGLKAIIAGAGGAAHLPGMVAAKTTLPVLGVPVQSKALSGQDSL
                     LSIVQMPKGIPVATFAIGEAGAANAGLFAMALLAVEDPALAQKLADFRARQTQAVLDM
                     SLD"
     gene            690..>1366
                     /locus_tag="P5537_16800"
     CDS             690..>1366
                     /locus_tag="P5537_16800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HRV79748.1"
                     /translation="MILPPATLGMLGGGQLGRFFVSAAHEMGYKVWVLDPDPHSPAGL
                     IADRHLVAAYDDYVALDTLGSGCAAVTTEFENVPADTLDYLTKFIPVHPAASAVAVCQ
                     NRIAEKTFLADHGLPHGPFAVIRGEDDVRNANAGLFPAILKVARFGYDGKGQARVADR
                     DEALAAFQHFKGEPCVLEKMLALDYEVSVVLARDEAGNVRAFPTGENRHRNGILDVTI
                     APARASA"
     assembly_gap    1367..1466
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <1467..1916
                     /locus_tag="P5537_16805"
     CDS             <1467..1916
                     /locus_tag="P5537_16805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HRV79749.1"
                     /translation="ERIADKLGYIGTLGVEFFVCRGELVVNEMAPRPHNSGHHTIDAC
                     DASQYEQQVRALCGLPLATPRQHSAAVMVNLLGELWYEDGKGHGAYREPEWSLLHAVP
                     GLRLHLYGKHHARPGRKMGHFVVTGDEAEVVLERALAARAAIGIRDE"
     gene            1927..3036
                     /locus_tag="P5537_16810"
     CDS             1927..3036
                     /locus_tag="P5537_16810"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HRV79750.1"
                     /translation="MSDSGARARGRIESATPGAISEAAALLRAGELVGMPTETVYGLA
                     ADALDPAAVKKIFAAKGRPADHPLIVHLPSAEHLPQWAAAIPKDAIALARAFWPGPLT
                     LILKRTPEVPDEVTGGQDTVGVRVPAHPVALALLRAFDGGLAAPSANRFGRISPTTAA
                     HVQEELGERVALILDGGACEVGIESTILDFSRDVPEILRPGAIGPEDIARVIGRRPRV
                     RGEVQLAVDERAVGQGRAELAGGRATGVVASAAADSAPRVSGALAAHYAPRTPLRLVE
                     PALLVDEAVALAGEGSRVTVLAHSTADPQDARLTWRSLPADPAAYAQGLYASLRALDA
                     LGADFILIEALPGGPGWRAVADRLGRAAVGSGSPD"
BASE COUNT          404 a         1127 c         1020 g          396 t
ORIGIN      
        1 atccacgccg gcaagctttg cggcgacgtg gatttcgagt cggcgaagga agtcgccggc
       61 gccatcaccc cggtgccggg cggcgtgggg ccgatgacca tcaccatgct gctggaaaac
      121 accgtgattt ccgccgagcg cgccgcgagt gatcgcaagc tcgcagccgg caagtgagga
      181 ctgcgagatg agcgaaaccc aacccgtcgt cggcatcatc atgggctcca actccgactg
      241 gcccaccatg aaggccgccg ccaagatgct ggaagacttc ggcgtgccct tcgaggcgcg
      301 cgtcgtctcc gcccaccgca cgcccgacct gatgttcgat tacgccgagg ccgcgcgcgg
      361 gcgcgggctc aaggcgatca tcgcgggtgc gggcggcgcg gcgcacctgc cgggcatggt
      421 cgctgccaag accacgctgc cggtgctggg cgtgccggtg cagtcgaagg ccctgtcggg
      481 gcaggattcg ctgctctcca tcgtgcagat gcccaagggc atcccggtcg ccaccttcgc
      541 catcggcgag gcgggcgcgg ccaacgccgg cctgttcgcg atggcgctgc tggcggtcga
      601 ggacccggcg ctggcgcaga agcttgccga cttccgtgcc cgccagaccc aggcggtgct
      661 cgacatgagc ctggattgag agccgcatca tgatcctccc gcctgccacc ctcggcatgc
      721 tcggcggcgg ccagctcggc cgctttttcg tttcggccgc gcacgagatg ggctacaagg
      781 tctgggtgct cgaccccgac ccgcacagcc ccgccggcct catcgccgac cgccacctgg
      841 tcgccgccta cgacgactac gtcgcgctcg acaccctggg tagcgggtgc gccgcggtga
      901 ccaccgagtt cgagaacgtc cccgccgaca cgctcgacta cctgaccaag ttcatcccgg
      961 tgcacccggc ggcgagcgcg gtcgcggtgt gccagaaccg catcgccgag aagaccttcc
     1021 tcgccgacca cggcctgccg cacggcccgt ttgcggtcat ccgcggcgag gacgacgtgc
     1081 gcaacgccaa cgccggcctg ttccccgcca tcctcaaggt cgcccgcttc ggctacgacg
     1141 gcaagggcca ggcccgcgtc gccgaccgcg acgaggcgct cgccgccttc cagcacttca
     1201 agggcgagcc ctgcgtgctg gagaagatgc tggcgctgga ctacgaggtg tcggtggtgc
     1261 tggcgcgcga cgaggcgggc aacgtgcgcg ccttcccgac cggcgagaac cgccaccgca
     1321 acggcatcct cgacgtgacc atcgcgccgg cgcgggcgtc ggcctgnnnn nnnnnnnnnn
     1381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1441 nnnnnnnnnn nnnnnnnnnn nnnnnngaac gcatcgccga caagctcggc tacatcggca
     1501 cgctgggcgt ggagttcttc gtctgccgcg gcgagctggt ggtcaacgag atggcgccgc
     1561 gcccgcacaa cagtggccac cacaccatcg acgcctgcga cgccagccag tacgagcagc
     1621 aggtgagggc gctgtgcggc ctgccgctgg ccacgccgcg ccagcactcg gcagcggtga
     1681 tggtgaacct gctcggcgag ctgtggtacg aggacggcaa gggccacggc gcctaccgcg
     1741 agcccgaatg gtcgctgctc cacgcggtgc ccggcctgcg tctgcacctg tacggcaagc
     1801 accacgcccg ccccgggcgc aagatgggcc acttcgtggt caccggcgac gaggccgagg
     1861 tcgtgctcga gcgcgcgctc gccgcgcgtg ccgcgatcgg catccgcgac gagtgagcac
     1921 gggccgatga gcgactccgg ggccagggcg cgcggccgca tcgaatccgc cacgccgggc
     1981 gcgatctccg aggcggccgc cttgctgcgc gcgggcgagc tcgtcggcat gccgaccgag
     2041 acggtctatg gcctggctgc ggatgcgctc gaccccgcgg cggtgaagaa gatcttcgcc
     2101 gccaagggcc gccccgccga ccatccgctg atcgtgcacc tgccctcggc cgagcacctg
     2161 ccgcagtggg ccgccgccat ccccaaggac gcgattgcgc tcgcgcgcgc cttctggccc
     2221 ggcccgctga cgctgatcct caagcgtacg cccgaggtcc ccgacgaggt caccggcggg
     2281 caggacaccg tcggcgtgcg cgtgcccgcg catccggtcg cgctcgcgct gctgcgcgcc
     2341 ttcgacggcg gcctggccgc gcccagcgcc aaccgcttcg gccgcatcag ccccaccacc
     2401 gccgcgcacg tgcaggaaga actcggcgag cgcgtggcgc tgatcctcga cggcggcgcc
     2461 tgcgaggtcg gcatcgaatc caccatcctc gacttctcgc gcgacgtgcc ggagatcctg
     2521 cgcccgggcg cgatcggccc ggaggacatc gcccgcgtca tcggccgccg gccgcgcgtg
     2581 cgcggcgagg tgcagctggc ggtcgatgag agggcggtcg ggcaggggcg tgcagagctt
     2641 gccgggggca gggccacggg cgtggtcgcg tctgccgcag ccgattccgc cccgcgcgtc
     2701 tccggcgcgc tggccgccca ctacgcgccg cggacgccgc tgcgtctggt cgagcccgcg
     2761 ctgctcgtcg acgaggccgt cgcgctcgcg ggcgagggca gccgcgtcac cgtcctcgcc
     2821 cattcgaccg ccgatccgca ggacgcccgc ctgacctggc gctccctgcc ggccgatccc
     2881 gccgcctatg cgcagggcct gtacgccagc ctgcgtgccc tcgacgccct cggtgcggac
     2941 ttcatcctga tcgaagcgct ccccggcggc cccggctggc gcgccgtcgc cgaccgcctc
     3001 ggccgcgccg ccgtcggctc cggcagcccc gactaagccc gtccgcc
//
LOCUS       DAOTIN010000215         3044 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_38114_length_3044_cov_7.417196, whole genome shotgun sequence.
ACCESSION   DAOTIN010000215 DAOTIN010000000
VERSION     DAOTIN010000215.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 3044)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3044)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3044
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_38114_length_3044_cov_7.417196"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(107..2584)
                     /gene="nirB"
                     /locus_tag="P5537_16815"
     CDS             complement(107..2584)
                     /gene="nirB"
                     /locus_tag="P5537_16815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012584884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008942 - nitrite reductase [NAD(P)H]
                     activity [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0042128 - nitrate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite reductase large subunit NirB"
                     /protein_id="HRV79751.1"
                     /translation="MKKMKLVLVGNGMAGVRTIEELLKLAPDLYDITVFGAEPHGNYN
                     RILLSPVLAGEMTLPEIMLNDVDWYRDNGITLHAGRKVVKIDRVRRKVLAGDGTEADY
                     DRLLLATGSTPFIPPIPGNDLPGVLGYRDIADTEAMIEAAGKYRHAVVIGAGLLGLEA
                     ANGLMLRGMDVTVVHIGDWIMERQLDKAAADMLQASLEAKGMKFLLARQTEALLPARN
                     ERGDMAERVGAVRFKDGMEIPADLVVVAAGIRPNYELAESAGLYCGGGRVRGIHVSDT
                     LQTVTDPRIYAVGECVAHRGVAYGLVAPLFEQGKVCANHLANFGIGRYEGSVTSTKLK
                     VTGIDVFSAGDFSGGPGTEDIVLHDRQGGVYKRVVLKDDRIVGSVLYGDTADGSWYFQ
                     LMKDRQSVAEIRDHLMFGQNRLGDAGHKGENRAASMPDTAEVCGCNGVCKGTIVKAIK
                     EKGLFTLDEVKKHTKAASSCGSCTGLVEQILASTVGGAYQAVSANDKPVCACTEHSHK
                     VVREAIFKHHLTTKEAVFDTLNWKTPNGCDKCRPAVNYYLISSWPHEARDDPQSRFIN
                     ERAHANIQKDGTYSVVPRMWGGLTTPSELRAIADAAEKYQVPTVKVTGGQRIDLLGVK
                     KEDLPAIWADLNAAGMVSGHAYGKSIRTVKTCVGAEHCRFGTQLAMDMGVKLEKMLFD
                     MYAPHKVKLAVSGCPRNCAEAGIKDVGVIGVDSGYELYVGGNGGIKTEVAQFLCKVGS
                     DEEVMEYSGAFLQLYREEGWYLERTVHWLNRVGLDYVKSKVVEDGDNRRRLHARLLDA
                     LKDARDPWQTSREEGAVKQFIPIQVEA"
BASE COUNT          454 a         1068 c         1002 g          520 t
ORIGIN      
        1 cggcaggcgc gaatgaggcg gtcggccgag cgtgatcgcc gatttcgtgc gccgcattcg
       61 cgcctgccgg cgctcctaca gggcgagcgc gaatgcggca cgtggctcac gcctccacct
      121 ggatcgggat gaactgcttc accgcgcctt cctcgcgact ggtctgccac gggtcgcggg
      181 cgtccttgag cgcgtcgagc aggcgggcgt gcaggcggcg gcggttgtcg ccgtcctcga
      241 ccaccttcga cttcacgtag tcgagcccca cgcggttcag ccagtgcacc gtgcgctcga
      301 gataccagcc ctcctcgcgg tagagctgca ggaaggcgcc ggaatactcc atcacctcct
      361 cgtcgctccc caccttgcac aggaactgcg cgacctcggt cttgatgccg ccgttgccgc
      421 cgacatacag ctcatagccg gaatcgacgc cgatcacgcc gacgtccttg atgccggctt
      481 ccgcgcagtt gcgcgggcag cccgacaccg cgagcttcac cttgtgcggc gcgtacatgt
      541 cgaacagcat cttctcgagc ttgaccccca tgtccatcgc cagctgcgtg ccgaagcggc
      601 agtgctcggc accgacgcag gtcttcacgg tgcggatcga cttgccgtag gcgtgtccgg
      661 acaccatgcc ggcggcgttg aggtcggccc agatcgccgg caggtcctcc ttcttcaccc
      721 cgagcaggtc gatgcgctgg ccgccggtga ccttcacggt gggcacctga tacttctcgg
      781 cggcgtccgc gatcgcgcgc aattcagaag gcgtggtcag cccgccccac atccgcggca
      841 ccaccgagta ggtgccgtcc ttctggatgt tggcgtgcgc gcgctcgttg atgaagcgcg
      901 actgcggatc gtccctggcc tcatgcggcc acgacgagat caggtagtaa ttgaccgccg
      961 gccggcactt gtcgcagccg ttgggcgtct tccagttgag cgtgtcgaac accgcctcct
     1021 tggtcgtcag gtggtgcttg aagatcgcct cgcgcaccac cttgtgcgaa tgctcggtac
     1081 aggcgcacac cggcttgtcg ttggcgctca ccgcctggta cgcgccgccc accgtagacg
     1141 cgaggatctg ctcgaccagg ccggtgcagg acccgcagga cgacgccgcc ttggtgtgct
     1201 tcttgacctc gtcgagcgtg aacagcccct tctccttgat cgccttgacg atggtgccct
     1261 tgcacacgcc gttgcagccg cacacctcgg ccgtgtcggg catgctggcg gcgcggttct
     1321 cgcccttgtg gccggcgtcg cccagcctgt tctggccgaa catcaggtgg tcgcggatct
     1381 cggccacgct ctggcggtcc ttcatcaact ggaagtacca cgagccatcg gcggtgtcgc
     1441 cgtacagcac cgagccgacg atgcggtcgt ccttgagcac gacgcgcttg tacaccccgc
     1501 cctggcggtc gtgcagcacg atgtcctcgg tgcccgggcc gccgctgaaa tctccggcgg
     1561 agaagacgtc gatgccggtg accttgagct tggtcgaggt caccgagccc tcgtagcggc
     1621 cgatgccgaa gttggcgagg tggttggcgc acaccttgcc ctgctcgaac agcggcgcga
     1681 ccaggccgta ggcgacgccg cggtgcgcca cgcactcgcc caccgcgtag atgcgcgggt
     1741 cggtgacggt ctgcagcgtg tcggagacat ggatgccgcg cacccggccg ccgccgcaat
     1801 acagcccggc ggactcggcg agctcgtagt tcggccggat gccggcggcg accacgacca
     1861 ggtcggcggg gatctccatg ccgtccttga agcgcaccgc gccgacgcgc tcggccatgt
     1921 caccgcgctc gttgcgcgcc ggcagcagcg cctcggtctg gcgcgcgagc aggaacttca
     1981 tgcccttggc ctcgagcgag gcctgcagca tgtcggccgc agccttgtcg agctggcgct
     2041 ccatgatcca gtcgccgatg tgcaccacgg tcacgtccat gccgcgcagc atcaggccgt
     2101 tggcggcctc cagcccgagc aggccggcgc cgatcaccac cgcgtggcgg tacttgccgg
     2161 cggcctcgat catcgcctcg gtgtcggcga tgtcgcggta gccgagcacg ccgggcaggt
     2221 cgttgccggg gatgggcggg atgaagggcg tcgagccggt cgccagcagc aggcggtcgt
     2281 agtcggcctc ggtaccgtcg ccggcgagca ccttgcggcg cacgcggtcg atcttcacca
     2341 ccttgcgccc ggcgtgcagg gtgatgccgt tgtcgcggta ccagtcgaca tcgttgagca
     2401 tgatctcggg cagcgtcatc tcgcccgcca gcaccggcga cagcaggatg cggttgtagt
     2461 tgccatgggg ctcggcgccg aacacggtga tgtcgtagag gtcgggcgcg agcttgagca
     2521 gctcctcgat cgtgcgcacg cctgccatgc cgttgccgac caggacgagt ttcatcttct
     2581 tcatggggta tctccgcaac aaggccgatt gggtcgaaat gaaaacggcg cccactccgc
     2641 tcgcgcccgt gcggggcgag tggaatggac gccgttgtcc accagaccgt aaaacgctgc
     2701 ggcagcgctc gctgccgctc acccgaccgc cgttggccag gggcttgcat gggaataagc
     2761 atcaaacatg ccagggggtg gcgggccgtt ggaacgtggc cggtcgtcac ccaccgccag
     2821 ccacgaccgc ccgcagccgc ccttcgccaa accggcattc gcactgctgc agtgcaacag
     2881 ccaagggccg atgcacaagc ctggtgcgga aagcgaacac ccgctccgcc cttcgcggct
     2941 gccgccgctc ctacattgcg ccgggccgcg tcggcatcgt cccacgccgc gtcgacatcg
     3001 tcccaatccg caccggttca tgtaggagcg ccggcaggcg cgaa
//
LOCUS       DAOTIN010000216         2967 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_39433_length_2967_cov_9.280907, whole genome shotgun sequence.
ACCESSION   DAOTIN010000216 DAOTIN010000000
VERSION     DAOTIN010000216.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 2967)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2967)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2967
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_39433_length_2967_cov_9.280907"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1304)
                     /locus_tag="P5537_16820"
     CDS             complement(<1..1304)
                     /locus_tag="P5537_16820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004357152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HRV79752.1"
                     /translation="MTSQGNSAGNDAPQQGGAVLTFEGSPFRLHQPFPPAGDQPEAIR
                     LLCEGVEDGLMYQTLLGVTGSGKTYTMANVIARMGRPALVLAPNKTLAAQLYAEFKEF
                     LPENAVEYFVSYYDYYQPEAYVPSRDLFIEKDSSINEHIEQMRLSATKSLMERRDVVI
                     VATVSCIYGIGDPVDYHAMILHLREGERMAHRDLIQRLVAMQYTRADIDFRRGTFRVR
                     GDVIDVFPAENAELAVRIEMFDDEIEHLTLFDPLTGHLKHKLARFTVYPSSHYVTPRA
                     TVLQAIEAIKEELKERVAFFQREGKLVEAQRIEQRTRFDLEMLNEMGFCKGIENYSRH
                     LSGRGPGEPPPTLIDYLPQDALLFIDESHVAIGQVGGMYKGDRSRKENLMGYGFRLPS
                     ALDNRPLKFDEFERLMPQTVFVSATPAKYEEEHQGQVVEQVVR"
     gene            1456..2664
                     /locus_tag="P5537_16825"
     CDS             1456..2664
                     /locus_tag="P5537_16825"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004343810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid aminotransferase"
                     /protein_id="HRV79753.1"
                     /translation="MSASIFAAVEMAPRDPILGLNEAFAADTRAEKVNLGVGVYYDDN
                     GKIPLLAAVRAAEKVRLEAMPPRGYQPIEGPAAYNNAVQGLLFGKDSQLATSGQTITV
                     EALGGTGALKVGADYLKRLVPGATVYISDPSWENHRALFESAGFPVENYPYYDAATRG
                     VNFAGMKAKLDSLQPGSIIVLHACCHNPTGADLSDAQWDEVVDVCRERGLIPFLDMAY
                     QGFAEGIDADAVAVRALSSSGLQFFVSSSFSKSFSLYGERVGALSIVTASKEEAGRVL
                     SQVKRVIRTNYSNPPIHGGAIVAAVLSSPELRQMWEDELGGMRERIRAMRTGLVEQLK
                     AAGVAQDFSFVIKQRGMFSYTGLTAAQVEQLKADFGIYAVSTGRICLAALNSKNIGYV
                     AKAIAQVVKG"
     gene            2761..2836
                     /locus_tag="P5537_16830"
     tRNA            2761..2836
                     /locus_tag="P5537_16830"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2794..2796,aa:Asn,seq:gtt)
BASE COUNT          488 a         1033 c          937 g          509 t
ORIGIN      
        1 cgcaccacct gctccaccac ctgcccctgg tgctcctcct cgtacttcgc cggcgtggcg
       61 gagacgaaca cggtctgcgg catcaggcgc tcgaactcgt cgaacttgag cggccggttg
      121 tccagcgccg agggcaggcg aaagccgtag cccatcaggt tctccttgcg agagcggtcg
      181 cccttgtaca tgccgccgac ctggccgatg gccacgtgcg actcgtcgat gaacagcagc
      241 gcgtcctgcg gcaggtagtc gatcagcgtc ggcggcggct cgcccgggcc gcgccccgac
      301 agatggcgcg agtagttctc gatgcccttg cagaagccca tctcgttgag catctcgaga
      361 tcgaagcggg tgcgctgctc gatgcgctgc gcctccacca gcttgccctc gcgctggaag
      421 aaggcgacgc gctccttcaa ctcctccttg atcgcctcga tcgcctgcag cacggtcgcg
      481 cgcggggtca cgtagtggct ggacggatac acggtgaagc gcgccagctt gtgcttgagg
      541 tggccggtga gcgggtcgaa cagggtcagg tgctcgatct cgtcgtcgaa catctcgatg
      601 cgcaccgcga gctcggcgtt ctcggccggg aagacgtcga tcacgtcgcc gcgcacgcgg
      661 aaggtgccgc ggcgaaagtc gatgtcggcg cgggtgtact gcatcgccac caggcgctgg
      721 atgaggtcgc ggtgcgccat gcgctcgccc tcgcgcaggt gcaggatcat ggcgtggtaa
      781 tcgaccgggt cgccgatgcc gtagatgcac gacaccgtgg ccacgatcac cacgtcgcgg
      841 cgctccatca ggctcttggt cgccgacagc cgcatctgct cgatgtgctc gttgatcgac
      901 gagtccttct cgatgaagag gtcgcgcgag ggcacgtagg cctcgggctg gtagtagtcg
      961 tagtagctga cgaagtactc gaccgcgttc tcgggcagga actccttgaa ctcggcgtag
     1021 agctgcgccg ccagcgtctt gttgggcgcc agcaccagcg ccgggcggcc catgcgggcg
     1081 atcacgttgg ccatggtgta ggtcttgccc gagccggtca cgcccagcag ggtctggtac
     1141 atcaggccgt cctcgacccc ttcgcacagc aggcggatgg cctcgggctg gtcgccggcg
     1201 ggcggaaagg gctggtgcag gcggaagggg ctgccttcga aagtgagcac cgcgccgcct
     1261 tgctgcggtg catcgtttcc ggcgctattg ccttgactcg tcatgctaaa attcccgctc
     1321 cattccggtg catcgccgca tggcgagacc ggacgaaaac gccgattatt tcccaaatcg
     1381 cgtgacaagg cacggcgtgt cgccgtcctc gccgcgcgca ctcaccgctg ccctaccgga
     1441 acaactggag tcctcatgtc cgcttcgatc ttcgccgccg tcgagatggc gccccgtgac
     1501 ccgatccttg gcctgaacga ggccttcgcc gccgacaccc gcgccgagaa ggtcaacctc
     1561 ggcgtcggcg tgtactacga cgacaacggc aagatcccgc tgctcgccgc cgtgcgcgcg
     1621 gccgagaagg tccgcctcga agccatgccg ccgcgcggct accagccgat cgaaggcccc
     1681 gccgcctaca acaacgcggt gcagggcctg ctcttcggca aggactcgca gctcgccacc
     1741 agcggccaga ccatcaccgt cgaggccctc ggcggcaccg gcgcgctcaa ggtcggcgcc
     1801 gactacctca agcgcctcgt gcccggcgcc accgtgtaca tttccgaccc gagctgggag
     1861 aaccaccgcg cgctgttcga atccgccggc ttcccggtcg agaactaccc ctactacgac
     1921 gccgccaccc gcggagtgaa cttcgccggc atgaaggcca agctcgacag cctgcagccc
     1981 ggctcgatca tcgtgctgca cgcctgctgc cacaacccca ccggcgccga cctgtccgat
     2041 gcgcagtggg acgaagtggt cgacgtgtgc cgcgagcgcg gcctcatccc cttcctcgac
     2101 atggcctacc agggcttcgc cgaaggcatc gacgccgacg ccgtggccgt gcgcgccctg
     2161 tcgtccagcg gcctgcagtt cttcgtgtcg agctcgttct cgaagagctt ctcgctctac
     2221 ggcgagcgcg tcggcgcgct gtccatcgtc accgccagca aggaagaagc cggccgcgtg
     2281 ctgtcgcagg tcaagcgcgt gatccgcacc aactactcca acccgccgat ccacggcggc
     2341 gccatcgtcg ccgcggtgct gtcctcgccc gagctgcgcc agatgtggga agacgagctc
     2401 ggcggcatgc gcgagcgcat ccgcgccatg cgcaccggcc tggtcgagca gctcaaggcc
     2461 gccggcgtgg cgcaggactt ctccttcgtg atcaagcagc gcggcatgtt ctcctacacc
     2521 ggcctcaccg ccgcccaggt cgagcagctg aaggccgatt tcggcatcta cgccgtgtcg
     2581 accggccgca tctgcctggc cgcgctcaac tccaagaaca tcggctacgt cgccaaggcg
     2641 atcgcgcagg tggtcaaggg ctgaaacctt tcgcgagtcc gggcgcaggc agctttcctc
     2701 aaaaaatgcc gccttcgcct tgactcaagc gcgttccctg cctaaaatgc gcgcctctgt
     2761 tccccgatag ctcagtcggt agagcgccgg actgttaatc cgtaggtccc tggttcgagc
     2821 ccaggtcggg gagccaagtt tcaggacttg gtgtttctca ccggaacagc aagttgcaca
     2881 gcatcaatcg cagcgaaggc tgcaagaggt aattccccga tagctcagtc ggtagagcgc
     2941 cggactgtta atccgtaggt ccctggt
//
LOCUS       DAOTIN010000217         2955 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_39650_length_2955_cov_8.841724, whole genome shotgun sequence.
ACCESSION   DAOTIN010000217 DAOTIN010000000
VERSION     DAOTIN010000217.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 2955)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2955)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2955
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_39650_length_2955_cov_8.841724"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..280)
                     /locus_tag="P5537_16835"
     CDS             complement(<1..280)
                     /locus_tag="P5537_16835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HRV79754.1"
                     /translation="MRKKIPSTAALLAFESAARHESFTRAAEELALTQSAICRQIGAL
                     EDFLGVPLFRRTRRGVQLTEAGLSYSRQIAPRLDAIEHDTLAVMAHHGE"
     gene            423..1610
                     /locus_tag="P5537_16840"
     CDS             423..1610
                     /locus_tag="P5537_16840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004377970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HRV79755.1"
                     /translation="MASNKASFNWDDPLLLDLQLTETERMVRDAARAYCQDKLLPRVQ
                     EAFRHEKTDAAIFREMGELGLLGPTIPEQYGGSGLNYVCYGLIAREVERVDSGYRSMM
                     SVQSSLVMVPINEFGTEAQKQKYLPKLATGEWIGCFGLTEPNHGSDPGSMITRARKVD
                     GGFSLSGSKMWITNSPIADVFVVWAKDDEGQIRGFILEKGWKGLSAPAIHGKVGLRAS
                     ITGEIVMDEVFVPEENAFPTVRGLKGPFTCLNSARFGIAWGALGAAEACYEAARQYTM
                     DRNQFGRPLAANQLIQKKLADMLTEITLGLQAVLRVGRMKDEGIAPVEITSIVKRNSC
                     GKALDIARMARDMLGGNGISDEYPVARHLVNLEVVNTYEGTHDVHALILGRAITGIAA
                     FSN"
     gene            1628..2851
                     /locus_tag="P5537_16845"
     CDS             1628..2851
                     /locus_tag="P5537_16845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002944545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CaiB/BaiF CoA-transferase family protein"
                     /protein_id="HRV79756.1"
                     /translation="MPGALSHVRVLDLSRILAGPWAGQMLADLGADVIKVERPGAGDD
                     TRGWGPPWLKDEQGADTSVAAYYLCANRNKRSITIDITQAEGQALVRRLAAESDVVLE
                     NFKVGGLAQYGLDYDSLKAVNPRLVYCSITGFGQDGPYAPRAGYDFLIQGLGGLMSIT
                     GRPDGEEGGGPMKVGVALTDILTGLYATNAVLAALAWRDKSGEGQYIDMALLDVQVAC
                     LANQAGNYLATGQSPQRLGNAHPNIVPYQDFPTADGYMILAIGNDGQFARFCAAAGAP
                     QLASDERFATNRARVVNRATLIPLLKKLTVERSTADWIARLEALAVPCGPINTLADVF
                     ADPQVQARGLKVTMPHPVAGQVPLVASPMKLSATPVDYRLPPPMLGEHTDEILAATLG
                     LDAAAIARLRADGVV"
BASE COUNT          502 a         1051 c          978 g          424 t
ORIGIN      
        1 gctcgccgtg gtgggccatc accgcgagcg tatcgtgctc gatcgcatcc agccgggggg
       61 cgatctggcg gctgtagctc agccccgcct cggtgagctg cacgccgcgc cgggtgcggc
      121 ggaacagcgg cacgccgagg aaatcctcca gtgcgccgat ctgccggcag attgcgctct
      181 gcgtgagcgc gagctcctcg gcggcgcggg tgaagctctc gtggcgcgcg gcggactcga
      241 aggcgagaag ggcggcggtg ctggggatct tcttgcgcat ggcggtcggt cttgcctctc
      301 ggagttcctg aagcgcacag attactgcag aaatatcgct tgagctgtgc ttccggagtt
      361 cataggatgc gattcaggca caggcagccg cctgcgcgac cgatcgcacg aggagacacg
      421 acatggcttc gaacaaggct agcttcaact gggacgaccc cctgctgctc gatctgcagc
      481 tcaccgagac cgagcgcatg gtgcgcgacg cggcgcgcgc ctattgccag gacaagctgc
      541 tgccgcgcgt gcaggaggcc ttccgccacg agaagaccga cgccgcgatc ttccgcgaga
      601 tgggcgagct gggcctgctc ggccccacca tccccgagca gtacggcggc tccggcctga
      661 actacgtgtg ctacggcctg atcgcgcgcg aggtcgagcg cgtcgattcc ggctaccgct
      721 cgatgatgag cgtgcagagc tcgctggtca tggtgccgat caacgagttc ggcaccgagg
      781 cgcagaagca gaaatacctg cccaagctcg ccaccggcga gtggatcggc tgtttcggcc
      841 tcaccgagcc gaaccacggc tccgatccgg gctcgatgat cacccgtgcg cgcaaggtcg
      901 atggcggctt cagcctgtcg ggcagcaaga tgtggatcac caacagtccg atcgccgacg
      961 tcttcgtggt gtgggccaag gacgacgagg gccagatccg cggcttcatc ctcgagaagg
     1021 gctggaaggg cctgtctgcg cccgccatcc acggcaaggt cggcctgcgc gcctcgatca
     1081 ccggcgagat cgtcatggac gaggtcttcg tgccggaaga gaacgccttc ccgaccgtgc
     1141 gcggcctcaa gggccccttc acctgcctca actcggcacg cttcggcatc gcctggggtg
     1201 cgctcggcgc ggccgaggcc tgctacgagg ccgcccgcca gtacacgatg gaccgcaacc
     1261 agttcggccg tccgctcgcc gccaaccagc tcatccagaa gaagctcgcc gacatgctca
     1321 ccgagatcac cctcggcctg caggcggtgc tgcgcgtggg ccgcatgaag gacgagggca
     1381 tcgccccggt cgagatcacc tcgatcgtca agcgcaactc ctgcggcaag gcgctcgaca
     1441 tcgcccgcat ggcgcgtgac atgctcggcg gcaacggcat ctcggacgag tacccggtgg
     1501 cccgccacct ggtgaacctc gaggtggtca acacctacga aggcacccac gacgtccatg
     1561 cgctgatcct cggccgcgcc atcaccggca tcgccgcgtt cagcaactga gcccacggag
     1621 agccccgatg cccggcgccc tgtcgcacgt ccgcgtcctc gacctctcgc gcatcctggc
     1681 cggcccctgg gccgggcaga tgctggccga cctcggtgcg gacgtcatca aggtcgagcg
     1741 tcccggcgcc ggcgacgaca cccgcggctg gggcccgccc tggctcaagg acgagcaggg
     1801 cgccgacacc agcgtggcgg cgtactacct gtgcgccaac cgcaacaagc gctcgatcac
     1861 catcgacatc acccaggccg agggccaggc gctggtgcgc cggctcgccg ccgagtccga
     1921 cgtggtgctg gagaacttca aggtcggcgg cctcgcacag tacggcctcg actacgacag
     1981 cctgaaggcg gtcaatccgc gcctggtgta ttgctcgatc accggcttcg gccaggacgg
     2041 gccgtatgcg ccgcgcgccg gctacgactt cctgatccag ggcctgggcg ggctgatgag
     2101 catcaccggc cggcccgacg gcgaggaggg cggcggcccg atgaaggtgg gcgtggcgct
     2161 caccgacatc ctcaccggcc tgtacgccac caacgcggtg ctcgccgcgc tggcctggcg
     2221 cgacaagagc ggcgagggcc agtacatcga catggcgctg ctcgacgtgc aggtggcctg
     2281 cctcgccaac caggcgggca actacctcgc caccggacag agcccgcagc ggctgggcaa
     2341 tgcgcacccc aacatcgtgc cctaccagga cttccccacc gccgacggct acatgatcct
     2401 cgccatcggc aacgacgggc agttcgcgcg cttctgcgcg gccgccggcg cgccacagct
     2461 cgcaagcgac gaacgcttcg ccaccaaccg cgcgcgcgtc gtcaatcgcg cgacgctgat
     2521 cccgctgctg aagaagctca ccgtcgagcg cagcaccgcg gattggatcg ccaggctcga
     2581 ggccctcgcc gtgccctgcg gcccgatcaa caccctcgcc gacgtcttcg ccgacccgca
     2641 ggtgcaggcg cgcgggctga aggtgacgat gccgcatccg gtcgccggcc aggtgccgct
     2701 ggtggccagc ccgatgaagc tgtcggccac gccggtcgac taccgcctgc cgccgccgat
     2761 gctgggcgag cacaccgacg agatcctcgc cgccacgctc ggcctcgacg ccgcggcgat
     2821 cgcccgcctg cgcgccgacg gcgtggtctg agcgggaaca agaagataca agacgaacac
     2881 aagggaacag catgaagatc ctcgtacccg taaagcgcgt ggtcgattac aacgtcaagg
     2941 ttcgcgtgaa ggccg
//
LOCUS       DAOTIN010000218         2751 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_43582_length_2751_cov_11.946217, whole genome shotgun
            sequence.
ACCESSION   DAOTIN010000218 DAOTIN010000000
VERSION     DAOTIN010000218.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 2751)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2751)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2751
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_43582_length_2751_cov_11.946217"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..849)
                     /locus_tag="P5537_16850"
     CDS             complement(<1..849)
                     /locus_tag="P5537_16850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sirohydrochlorin chelatase"
                     /protein_id="HRV79757.1"
                     /translation="MNDTVLLLVGHGSRKREGNKEILHFAAQWRERHPGWRIETCFIE
                     HADVLLDEGLDRAARDTRHVLAIPFILNAAGHVKMELPAALARARARHPGVGFACTRH
                     LGMGREIFAVLRGQLDRLMRQLAMPDPQTTGVVLLGRGSSDAGANGELARMARWIFED
                     GDHELVDLAFTGVTWPRLETVVQRQARLGMTQVCIVPAYLFTGVLMERIHAQVERLQH
                     QYPQVAFALGTHFGFDEGIFNLLDARVAEGCAGLADAAAAHGLLECDGCRYRLAAEDE
                     HLHDHSH"
     gene            complement(846..1664)
                     /gene="cobM"
                     /locus_tag="P5537_16855"
     CDS             complement(846..1664)
                     /gene="cobM"
                     /locus_tag="P5537_16855"
                     /EC_number="2.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004306982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0046026 - precorrin-4
                     C11-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-4 C(11)-methyltransferase"
                     /protein_id="HRV79758.1"
                     /translation="MSALRGTVWFVGAGPGDPDLITVKGRRLLEQAGAILFAGSLVDQ
                     AATQHAPQGCEIRDSRDMTLEEMNAWLAEACARHETVVRLQTGDPGLYGALVELTRPL
                     DAAGIPWRVVPGVSSAMAAAAAAGETLTLPEVTQTVILTRVAGRTPMPAGEELEALAA
                     HRSTLCIFLSITLLHEVQRALRAAGWPEDAPIVVVHKASWPGAEKVVRGTLADIKRRC
                     QDEKIASQAMILASPALGARLWPDIARSKLYDPGFGHRFRKASMPAGIATGESA"
     gene            complement(1664..2302)
                     /locus_tag="P5537_16860"
     CDS             complement(1664..2302)
                     /locus_tag="P5537_16860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HRV79759.1"
                     /translation="MHIEPGILSGAKIAAANLAAIALVAAQAPQLLRKPQLVLRTLLA
                     ALLFSVFMQSFHLPAGASELHFIGAMPIYLTLGFVPALLGFGLGLLLQGVVFEPADLL
                     HLGVNFLSLAVPLLALHATLGRRLAAGAATRIGAVLRLDAAYYAGVALMVGFWLAMGE
                     VATPFAEWTAFAAAYLPVVLIEPVFTVAAVRLLQSQAHRPLVQLCFAVPARG"
     regulatory      complement(2573..>2751)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
BASE COUNT          411 a          899 c         1073 g          368 t
ORIGIN      
        1 gtggctgtgg tcgtgcaggt gctcgtcctc ggcggcgagg cgatagcggc agccgtcgca
       61 ctcgagcagg ccgtgggcgg ccgcggcatc ggcgagaccc gcgcagccct cggcgacgcg
      121 tgcgtcgagc aggttgaaga tgccctcgtc gaagccgaag tgggtgccga gcgcgaaggc
      181 gacctgcggg tactggtgct gcaggcgctc gacctgggcg tggatgcgct ccatcagcac
      241 gccggtgaag aggtatgccg gcacgatgca gacctgtgtc atgccgaggc gggcctggcg
      301 ttgcaccacg gtctcgagcc gcggccaggt cacgccggtg aaggcgaggt cgaccagctc
      361 gtggtcgccg tcctcgaaga tccagcgcgc catcctggcg agctcgccgt tggcgccggc
      421 gtccgacgag ccgcggccga gcaggaccac gccggtggtc tgcggatcgg gcatggcgag
      481 ctggcgcatc aggcgatcga gctggccgcg cagcacggcg aagatctccc tgcccatgcc
      541 gaggtggcgg gtgcaggcga agccgacgcc ggggtgacgc gcgcgggcgc gtgcgagcgc
      601 ggcgggcagt tccatcttga cgtggccggc ggcattgagg atgaagggga tcgcgagcac
      661 gtggcgggtg tcgcgcgcgg cgcggtcgag gccctcgtcg agcagcacgt cggcgtgctc
      721 gatgaagcag gtctcgatgc gccagccggg atggcgctcg cgccattgcg cggcgaagtg
      781 caggatctcc ttgttgccct cgcgcttgcg cgagccgtgg ccgacgagga ggaggacggt
      841 gtcgttcatg cggattctcc ggtggcgatg ccggccggca tcgacgcctt gcggaagcgg
      901 tggccgaagc cggggtcgta gagcttggag cgcgcgatgt ccggccacag gcgggcgccg
      961 agcgcggggc tggcgaggat catggcctgg ctggcgatct tctcgtcctg gcagcggcgc
     1021 ttgatgtcgg ccagggtgcc gcgcacgacc ttctccgcgc ccggccagct cgccttgtgc
     1081 accaccacga tcggagcatc ctccggccag ccggcggcgc gcagcgcgcg ctgcacctcg
     1141 tgcagcagcg tgatcgacag gaagatgcac aaggtgctgc ggtgggcggc gagggcttcg
     1201 agttcctcgc ccgcgggcat cggggtgcgc ccggcgacgc gggtgaggat gacggtctgg
     1261 gtgacttcgg gcagggtcag ggtctcgccg gccgcggcgg cggcggccat cgctgaggac
     1321 acccccggca ccacccgcca ggggatgccg gcggcgtcga gcgggcgggt cagctcgacc
     1381 agtgcgccgt acaggccggg gtcgccggtc tgcaggcgca ccacggtctc gtggcgcgcg
     1441 caggcttcgg ccagccaggc gttcatctct tcgagcgtca tgtcgcgcga gtcgcggatc
     1501 tcgcagccct gcggcgcgtg ctgtgtcgcc gcctgatcga ccagcgagcc cgcgaacagg
     1561 atcgcgcccg cctgctcgag caggcggcgg cccttcaccg tgatcaggtc cgggtcgccg
     1621 gggccggcgc cgacgaacca gaccgtgccg cgcagggcgc tcatcagccg cgcgccggga
     1681 cggcgaagca gagttgcacg agtgggcggt gggcctgcga ctgcagcagc ctgaccgcgg
     1741 ccacggtgaa caccggctcg atcagcacca ccggcaggta ggcggcggcg aacgccgtcc
     1801 actccgcgaa gggcgtggcg acctcgccca tggccagcca gaagccgacc atcagcgcga
     1861 cgccggcgta gtaggcggcg tcgagtctga gcaccgcgcc gatgcgggtg gcggcgccgg
     1921 cggcgagcct gcggccgagg gtggcatgga gcgcgagcag cggtacggcg agcgaaagga
     1981 aattcacccc caggtgcagc aggtcggccg gctcgaagac cacgccctgc agcagcaggc
     2041 caagcccgaa gccgagcagc gcgggcacga agccgagcgt gaggtagatc ggcatcgcgc
     2101 cgatgaagtg cagctccgac gcgcccgcgg gcaggtggaa gctctgcatg aagacggaga
     2161 agagcagcgc cgcgagcagc gtgcgcagga cgagctgcgg tttgcgcaag agctgcggcg
     2221 cctgggcggc gacgagcgcg atggcggcga ggttggcggc ggcgatcttg gcgccggaaa
     2281 ggatgccggg ttcgatgtgc atggtgactc cccacgagtg catggaacga cgatgcgaac
     2341 cacgcgggcg gggggcggca ggccttggca ggcacgggcg gccgacgcac ggacgcggcg
     2401 aaaccgcgga cgtacctcgg gcacggcagt gcctgatgac gcttgcacga cgagtcggct
     2461 ggagcttccg gcgcacgcgg gcagccggcg gaaaaccagt cggatcgaac ccacaccccg
     2521 gggctcacat caacctggaa cctcgcacgg cgccgttttc acggcggctg cgagattccg
     2581 tactcgatcg ggccggtctt ctggctcgcc gtcttcctct tccgccgacc ttcccgagcg
     2641 cgaggctcag tggcgtgatg gcggattcgt caggcttaca gcagcggggg ctgcgccgga
     2701 atggtcgtgc gcgcgcaagg cggacgactt caccggactt cccgtttcac c
//
LOCUS       DAOTIN010000219         2709 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_44503_length_2709_cov_8.448003, whole genome shotgun sequence.
ACCESSION   DAOTIN010000219 DAOTIN010000000
VERSION     DAOTIN010000219.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 2709)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2709)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2709
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_44503_length_2709_cov_8.448003"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            222..497
                     /locus_tag="P5537_16865"
     CDS             222..497
                     /locus_tag="P5537_16865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004336392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HRV79760.1"
                     /translation="MNSLTKDTRLHIRCDQEVRRLLDKAAAYAHMSVSEFVLRNAVEQ
                     AQTLVQQHEAITLSQQDFSAFLDALDSPAHPAPALQRAFARHANQVR"
     gene            498..998
                     /locus_tag="P5537_16870"
     CDS             498..998
                     /locus_tag="P5537_16870"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004336391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HRV79761.1"
                     /translation="MKYGIRALDNETATADFRCGEAALDEYLHRHARQDVKRGVARVF
                     VATPADLVSEVAGFYTLSAASVAAEKLPESLRKKLPRYPVPAALLGRLAVSVLAQGQG
                     LGSILLVDACKRVAAASQTLAVAAIIVDAKSPAAAAFYKHFGFVELPGQQGRWMLPRS
                     HFVQGL"
     gene            1118..2530
                     /gene="gltX"
                     /locus_tag="P5537_16875"
     CDS             1118..2530
                     /gene="gltX"
                     /locus_tag="P5537_16875"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009332 - glutamate-tRNA ligase complex
                     [Evidence IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HRV79762.1"
                     /translation="MSQTSASRPVRTRFAPSPTGYLHIGGARTALFSWAFARRHAGTF
                     VLRIEDTDVARSTPAAVQAILDGMQWLGLEHDEGPFYQMQRMDRYKEVIGQMLAAGTA
                     YHCYMSSEELDQIREAQRARGEKPRYDGRWRPEAGKTLPPPPEGVQPVVRFCNPTEGV
                     VAWDDLVKGRIEIANAEMDDFIIARADGTPTYNFCVVVDDWDMGITHVIRGDDHVNNT
                     PRQINVLQALGAEVPLYAHLSMILGDDGTKLSKRHGAVSVMQYDEDGYLPEAVINYLA
                     RLGWSHGDDEVFSREQFVEWFDLDHITPSAAQFNTEKLNWLNAQYIRKAEDGFLAAEV
                     ANRLARREVNPETGVSLEAVVALYKDRVANLNELADAAELFVADVHPAPEVVGQHLTD
                     VAKVALASLRVRLAAAEWNKAALSQAIKDTMAEHGLKMPQVAIPLRVAVLGVPQTPAI
                     DAVLEVLGRERVLERLDRRL"
BASE COUNT          454 a          889 c          900 g          466 t
ORIGIN      
        1 tcttgcaaga attgcgtatt tgaatcaatg cacatcgggt agtttcaaaa gtccatatga
       61 gcggcagctt gacgacctgc atgctgtcgt cgcgcttgag aatgtcatca ggcggctccg
      121 ggtcggatgc agtcagcaag cgcggcgagg gatcgtgctc atccttgagt tgtgcgcacg
      181 aatggcgcac aatgaacgca ttgttttcct aggagcgctc gatgaactcc ctgaccaaag
      241 acacccgcct gcacatccgt tgtgaccagg aagttcggcg tctgctcgac aaggcggcgg
      301 cctatgcgca catgagcgtg tcggagttcg tgctgcgaaa cgctgtcgag caagcccaga
      361 ccctggttca gcagcacgag gccatcacgc tgtcgcagca ggatttttcc gcgtttctcg
      421 atgccctgga ttcaccggct caccccgctc cggccttgca gagggcgttc gcccgccacg
      481 ccaaccaggt gcgctgagtg aagtatggca ttcgcgcgct cgacaacgag acggcgaccg
      541 ccgattttcg atgtggggag gcggcgctgg atgaatacct gcaccgccat gccaggcagg
      601 acgtcaagcg cggagtggcg cgggtgttcg tggcgacgcc ggccgatctg gtcagcgagg
      661 tcgcaggctt ctacacactg agtgcagcca gcgttgccgc cgaaaagcta cccgagtcct
      721 tgcgcaagaa gctgccgcgt taccccgtcc ctgccgcctt gctcggtcgg ctagccgtga
      781 gtgtactggc gcaagggcag ggcttgggtt ccatcttgct ggtcgatgct tgcaagcggg
      841 tggccgcggc cagccagacg ctcgcggtgg cggccatcat cgtcgatgcc aaatcgcccg
      901 cggcggctgc tttctacaag cacttcggat ttgtcgagct tcctggccag caggggcgct
      961 ggatgttgcc gagatctcac ttcgttcaag gcctttgaac gtcagattgt tttgggcgaa
     1021 tggctgtcct cgccgcgctt tcctcccctc acgaccgccg atgtcacggg cgatcgctta
     1081 gaatccgcgc tttgcccaag actgcatcca cgctcccatg tcccagacct ccgcttcccg
     1141 tcccgtccgc acccgcttcg cccccagccc caccggctac ctgcacatcg gcggcgcgcg
     1201 caccgcgctg ttctcctggg ccttcgcccg tcgccacgcc ggcaccttcg tgctgcgcat
     1261 cgaggacacc gacgtcgcgc gctccacccc cgcggcggtg caggcgatcc tcgacggcat
     1321 gcagtggctg ggcctggagc acgacgaggg cccgttctac cagatgcagc gcatggaccg
     1381 ttacaaggag gtcatcggcc agatgctggc cgccggcacc gcctaccact gctacatgtc
     1441 gtccgaggag ctcgaccaga tccgcgaggc acagcgcgca cggggcgaga agccgcgcta
     1501 cgacgggcgc tggcgccccg aggcgggcaa gaccctgccg ccgccgcccg agggcgtgca
     1561 gccggtggtg cgcttctgca atccgaccga aggcgtggtg gcatgggacg acctggtcaa
     1621 gggccgcatc gagatcgcca acgccgagat ggacgacttc atcattgcgc gcgccgacgg
     1681 cacgcccacc tacaacttct gcgtggtggt ggacgactgg gacatgggca tcacccacgt
     1741 cattcgcggc gacgaccacg tgaacaacac cccgcgccag atcaacgtgc tgcaggcgct
     1801 cggcgccgag gtgccgctgt atgcgcacct gtcgatgatc ctcggcgacg acggcaccaa
     1861 gctctccaag cgccacggcg cggtgagcgt gatgcagtac gacgaggacg gctacctgcc
     1921 cgaggcggtg atcaactacc tggcgcgcct gggctggagc catggcgacg acgaggtctt
     1981 cagtcgcgag cagttcgtcg agtggttcga cctcgaccac atcacgccat cggccgcgca
     2041 gttcaacacc gagaagttga actggctcaa cgcgcagtac atcaggaagg cggaggacgg
     2101 cttcctcgcc gcggaggttg ccaatcgcct ggcgcgtcgc gaggtgaatc ccgagaccgg
     2161 ggttagcctg gaggcggtgg tggcgctgta caaggatcgc gtggccaacc tcaacgagct
     2221 ggccgatgcc gccgagctgt tcgtggccga cgtgcatccg gcgccggagg tggtgggcca
     2281 gcacctgacg gacgttgcca aggtcgcgct cgccagcctg cgtgtgcgcc tggctgcggc
     2341 ggagtggaac aaggcggcgc tcagccaggc gatcaaggac acgatggccg agcatggcct
     2401 gaagatgccg caggtggcga tcccgctgcg tgtggcggtg ctcggcgtgc cgcagacgcc
     2461 ggcgatcgac gccgtgctgg aggtgctcgg tcgcgagcgc gtgctcgagc gcctggatcg
     2521 ccgcctctga gatcggcgct gttttcgcgg ctgccgccgc tcgtacaggg ggccgcaagc
     2581 gcgacggttc atgtaggagc gccggcaggc gcgaaggcca tgggcgagat tctgcctgcg
     2641 agtcggtcgc tcatccgccc gattcgcagc tgccgcagct cctacaggcg ggtccgggac
     2701 gggcgccgg
//
LOCUS       DAOTIN010000220         2638 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_46137_length_2638_cov_9.077042, whole genome shotgun sequence.
ACCESSION   DAOTIN010000220 DAOTIN010000000
VERSION     DAOTIN010000220.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 2638)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2638)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2638
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_46137_length_2638_cov_9.077042"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            184..1029
                     /locus_tag="P5537_16880"
     CDS             184..1029
                     /locus_tag="P5537_16880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018991100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF364 domain-containing protein"
                     /protein_id="HRV79763.1"
                     /translation="MTFATDLIAELERATAGHSIPRVRALHLPPPEAAESRNGEFCAL
                     ELDDGALGLSYVLLGGILPRLAASDDPHTIVGMDALQLAREFVAPTAGAGGDAEIRRT
                     LGFAAANALSRTVMERMGFAPPRAIDSIGGIDPQAGDHVGMVGLFTPLLKQVTAAGAQ
                     LTVIELNPDYAGHYDGYRVTLDAAALEDCNKVLSTSTILLNHTVDDMLAHCRRARRIV
                     LIGPSAGCLPDPLFARGVTVVGGSWITDRAGFIDALRRGESWSGFAYKFALAAADWPG
                     LPENR"
     gene            1095..2033
                     /locus_tag="P5537_16885"
     CDS             1095..2033
                     /locus_tag="P5537_16885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HRV79764.1"
                     /translation="MHLTPRLVFFLVLPPLLWAGNAVVGRLAIGSMDPLWLNAVRWML
                     AFVLLLPLGWRALGTPAALAQIRARWAHLAVLGLIGVGAYNALQYMALRTSTPLNVTL
                     IASSAPVWMMLIGAVFYRVIPRPVQVLGALLSLLGVALVLSRGDPTALARVEFVEGDL
                     LMLLAMLGWTGYSWMLARPPAHMAGEARPKWNWAEFLVAQCVFGVLWAVAAAAAGDVV
                     FPSGPTQWSWGLVAAIVYIAVGPSIIAYRSWGVAVAEAGPATAAIFYNLTPLFAAVFS
                     AAVIGEWPRPYHGIAFLLIVGGILVSTRAAARRQAA"
     gene            2030..2344
                     /locus_tag="P5537_16890"
     CDS             2030..2344
                     /locus_tag="P5537_16890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004371740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1992 domain-containing protein"
                     /protein_id="HRV79765.1"
                     /translation="MNAVFDLLAEQRILEALRNGDFDHLPGAGRPLVIEDEPFVSPEQ
                     RMANHILRNAGFAPPEIGLRREIARLRAEIAGLEEGSEPWRAQRRRLAEMIVQLQEMG
                     RG"
     gene            complement(2405..>2638)
                     /locus_tag="P5537_16895"
     CDS             complement(2405..>2638)
                     /locus_tag="P5537_16895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004371742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79766.1"
                     /translation="LEDRRRNGGGFRLKIRIHPDGPLIGWDLERGVGTGPDGSKFHHA
                     GGDFQEAYIYNGKVLRRGWYIHPKTGQRFETDY"
BASE COUNT          332 a          981 c          901 g          424 t
ORIGIN      
        1 cagccgcgaa tgcagcgctg cagcagctgg cacggttgcg ggcaatcgac gccgcattcg
       61 cgcctgccgg cgctcctaca ggggggtgtc cggccttcgg tagggatcgt cgagccttcg
      121 gggggcgtgc cgccgtggta ggctcgcccg accccaccgc ccggccttgc gccgttgtcc
      181 atcatgacct tcgccaccga cctgatcgcc gaactcgaac gcgccaccgc cggccactcg
      241 atcccgcgcg tgcgtgcgct gcacctgccg ccgccggagg cggccgagtc gcgcaacggc
      301 gagttctgcg cgctcgagct cgacgacggc gcgctcggcc tctcctacgt cctgctcggc
      361 ggcatcctgc cccggctcgc cgcctcggac gacccgcaca ccatcgtcgg catggatgcg
      421 ctgcagctcg cgcgcgagtt cgtcgcgccc accgccggcg cggggggcga tgcggagatc
      481 cgccgcacgc tcggcttcgc cgcggccaat gcgctgtcgc gcacggtgat ggagcgcatg
      541 ggcttcgcgc cgccgcgcgc catcgactcg atcggcggca tcgacccgca ggcgggcgac
      601 cacgtcggca tggtcgggct gttcacgccg ctgctgaagc aggtcaccgc cgccggcgcg
      661 cagcttaccg tgatcgagct caacccggac tacgccggcc actacgacgg ctaccgcgtc
      721 accctcgacg ccgccgcgct cgaagactgc aacaaggtgc tgtcgaccag caccatcctg
      781 ctcaaccaca cggtcgacga catgctcgcg cattgccgcc gggcgcggcg catcgtgctg
      841 atcggcccga gcgccggctg cctgcccgat ccgctgttcg cgcgcggcgt caccgtggtc
      901 ggcggcagct ggatcaccga tcgtgccggc ttcatcgacg cgctgcgccg cggcgagtcg
      961 tggagcggct tcgcctacaa gttcgcgctc gccgcggcag actggccagg gctgccggaa
     1021 aaccgctaag gttgcggcct cgcgtccggg cagcggccac gctgcccgca aaacaataaa
     1081 gatcgaaccc caacatgcac ctgactcccc gactcgtctt cttcctcgtc ctgccgcccc
     1141 tgctgtgggc gggcaatgcg gtcgtcggcc gcctcgcgat cggcagcatg gacccgctct
     1201 ggctcaacgc ggtgcgctgg atgctcgcct tcgtgctgct gctgccgctc ggctggcgcg
     1261 cgctcggcac acccgcggca cttgcgcaga tccgcgcgcg ctgggcccac ctcgcagtgc
     1321 tcggtctgat cggcgtgggt gcctacaacg cgctgcagta catggcgctg cgcaccagca
     1381 cgccgctcaa cgtcaccctg atcgcctcga gcgcgccggt gtggatgatg ctgatcggcg
     1441 ccgtgttcta ccgtgtcatc cctcgcccgg tgcaggtcct gggcgcgctg ctgtcgctgc
     1501 tcggcgtcgc gctggttctg tcgcgcggcg acccgaccgc gctcgcgcgc gtcgagttcg
     1561 tcgagggcga cctgttgatg ctgctcgcca tgctgggatg gaccggctac agctggatgc
     1621 tcgcccgccc gcccgcgcac atggcgggcg aggctcggcc gaaatggaac tgggccgagt
     1681 tcctcgtcgc ccagtgcgtc ttcggcgtgc tctgggcggt ggccgccgcc gccgcgggcg
     1741 acgtggtgtt cccgtccggg ccgacacagt ggtcctgggg cctggtcgcc gccatcgtct
     1801 acatcgccgt cggcccgtcg atcatcgcct accgctcctg gggcgtggcg gtggccgagg
     1861 ccgggccggc caccgcggcc atcttctaca acctcacccc gctcttcgcc gcggtgttct
     1921 ccgccgccgt catcggcgag tggccgcgcc cctaccacgg catcgccttc ctgctcatcg
     1981 tcggcggcat ccttgtcagc acccgcgccg cggcgcgacg acaggcggcg tgaacgcggt
     2041 cttcgatctg ctggctgagc agcgcatcct cgaggcgctg cgcaacggcg acttcgacca
     2101 tctccccggc gcgggtcggc cgctggtcat cgaggacgag cccttcgtct cccccgagca
     2161 gcgcatggcc aaccacatcc tgcgcaacgc cggcttcgcc ccgccggaga tcggcctgcg
     2221 ccgcgagatc gcgcggctgc gcgcggagat cgcagggctg gaggagggca gcgagccatg
     2281 gcgcgcgcag cgcaggcggc tggcggagat gatcgtgcag ctgcaggaga tggggcgggg
     2341 gtgaactaag gtcggagccc gtcgcatcgt cggcaacacg gtacgcaagc cttccggcgc
     2401 ggcttcaata gtcggtctcg aagcgctggc cggtcttggg gtggatgtac cagcccctgc
     2461 gcagcacctt gccgttgtag atgtaggcct cctggaagtc gcccccggcg tggtggaact
     2521 tggagccgtc gggcccggtt ccgactccgc gttcgagatc ccagccgatg agcgggccgt
     2581 ccgggtggat gcggatcttc agccgaaagc cgccgccgtt gcggcgccgg tcttcgag
//
LOCUS       DAOTIN010000221         2583 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_47469_length_2583_cov_9.364715, whole genome shotgun sequence.
ACCESSION   DAOTIN010000221 DAOTIN010000000
VERSION     DAOTIN010000221.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 2583)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2583)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2583
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_47469_length_2583_cov_9.364715"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..372)
                     /locus_tag="P5537_16900"
     CDS             complement(<1..372)
                     /locus_tag="P5537_16900"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79767.1"
                     /translation="MGQIHLRFLKRHSRSRARSRKKIGHKAIADKPNAHKKAGRARTG
                     FVVCTILVQKQRLYGVEGQAFQASCTILDTTVLLAAVEKLYPPKLAGFNSFFALRHAT
                     RTPAAMVLQERRQARRRRCRWR"
     gene            358..>2583
                     /locus_tag="P5537_16905"
     CDS             358..>2583
                     /locus_tag="P5537_16905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015930 - glutamate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006807 - nitrogen compound metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase central domain-containing
                     protein"
                     /protein_id="HRV79768.1"
                     /translation="MDLPHKQGLYDPANEHDACGVGFIAHIKGEKRHDIILQGLEILK
                     NLDHRGAVGADPLQGDGAGILIQIPDQLYREEMAAQGVSLPLPGEYGVGMVFMPKEAA
                     SRLACEQEIERAVVAEGQVVLGWRDVPVNRDMPMSPTVKAMEPVIRQIFIGRGPDVMV
                     TEALERKLYVVRRRSANAIGALKLKHAKEFYMVSCSARTVNYKGLLLADQVGEYYPDL
                     LDKRAVSALSLVHQRFSTNTFPKWNLAHPFRYIAHNGEINTLRGNYNWMRAREKGVHS
                     PLLGDDLQKIWPLIYPGQSDSASFDNALELLVMSGYSLAHAMMMMIPEAWESHTQMDE
                     KRRAFYEYHAAMMEPWDGPAAVAFTDGRQIGATLDRNGLRPARYLITDDDLVVMASES
                     GVLPIADSKIVKKWRLQPGKMFLIDMEQGRIIGDQEIKESLAHARPYADWLRRINIKL
                     DTLEAPAVLDTAAADERVAPLLDRQQAFGYTQEDIKFILEPMGKAGEEGTGSMGNDSP
                     LAVLSSKNKPLFNYFRQLFAQVTNPPIDPIREQMVMSLVSFIGPRPNLLEINEINPPF
                     RLEVSQPVLDFEGMAKIRNIARYTQNKFRSAELDICYPAEWGNEGVEARLASLCADAE
                     NAVLAGTNILIVSDRKLAADRVAIPALLALSAIHQHLVEKGLRTRTGLVVETGSAREV
                     HHFAVLAGYGAEAVHPYLALETLAHLADDAEAAAKYVKHFVKAIGKGLMKVMSKMGIS
                     TY"
BASE COUNT          453 a          900 c          816 g          414 t
ORIGIN      
        1 tcgccaccgg caccgccgcc ttcgcgcctg ccggcgctcc tgcagaacca tcgcggcagg
       61 ggttctcgtc gcgtgccgca gtgcaaaaaa actgttgaat ccggcgagct ttggggggta
      121 tagtttttcg accgcagcga gcaggacggt ggtgtccaaa atggtgcatg aggcctgaaa
      181 agcctgccct tcaaccccgt agagtcgctg tttctgcacc agaatggtgc agactacaaa
      241 gccggtgcgc gcgcgcccgg cttttttgtg cgcgttcggt ttgtcggcga tggccttgtg
      301 gccgattttt ttccggctcc gcgcgcgtga tcttgagtgt cgtttgagga atcgaagatg
      361 gatctgcccc ataagcaggg tctgtacgac cccgccaatg aacacgatgc ctgtggcgtg
      421 ggtttcatcg cccacatcaa gggcgagaaa cgtcatgaca tcattctgca gggcctcgag
      481 atcctgaaga acctcgacca ccgcggcgcg gtgggggccg acccgctgca gggcgacggc
      541 gcgggcatcc tgatccagat ccccgaccag ctctaccgtg aggagatggc cgcgcagggc
      601 gtgagcctgc cgctgcccgg cgagtacggc gtcggcatgg tgttcatgcc caaggaagcc
      661 gcctcgcgcc tcgcctgcga gcaggagatc gagcgcgcgg tcgtggccga aggccaggtc
      721 gtgctcggct ggcgcgacgt gccggtcaac cgcgacatgc cgatgtcgcc gacggtcaag
      781 gccatggagc cggtgatccg ccagatcttc atcggccgcg gtcccgacgt catggtcacc
      841 gaggcgctcg agcgcaagct ctacgtcgtg cgtcgccgct cggccaacgc catcggcgcg
      901 ctcaagctca agcacgccaa ggagttctac atggtgtcgt gctcggcgcg caccgtgaac
      961 tacaagggcc tgctgctcgc cgaccaggtc ggcgagtact accccgacct gctcgacaag
     1021 cgcgccgtgt cggcgctgtc gctggtgcac cagcgcttct cgacgaacac cttcccgaag
     1081 tggaacctcg cccacccgtt ccgctacatc gcccacaacg gcgagatcaa caccctgcgc
     1141 ggcaactaca actggatgcg cgcgcgcgag aagggcgtgc attcgccgct gctcggcgac
     1201 gacctgcaga agatctggcc gctgatctac cccggccagt ccgactcggc ttcgttcgac
     1261 aacgcgctcg agctgctggt gatgagcggc tactcgctcg cccacgcgat gatgatgatg
     1321 atccccgagg cctgggaatc gcacacgcag atggacgaga agcgccgcgc cttctacgag
     1381 taccacgcgg cgatgatgga gccctgggac ggccccgcgg cggtggcctt caccgacggc
     1441 cgccagatcg gcgccaccct cgaccgcaac ggcctgcgtc cggcgcgcta cctgatcacc
     1501 gacgacgacc tcgtggtgat ggcctccgag tccggtgtgc tgcccatcgc cgacagcaag
     1561 atcgtcaaga agtggcgcct gcagccgggc aagatgttcc tgatcgacat ggagcagggc
     1621 cgcatcatcg gcgaccagga gatcaaggag tcgctcgccc acgcgcgccc ctacgccgac
     1681 tggctgcgcc gcatcaacat caagctcgac accctcgagg ccccggccgt gctcgacacc
     1741 gccgccgccg acgagcgcgt cgcgccgctg ctcgaccgcc agcaggcctt cggctacacc
     1801 caggaggaca tcaagttcat cctcgagccg atgggcaagg cgggcgagga gggcaccggc
     1861 tcgatgggca acgactcgcc gctggcggtg ctgtcctcga agaacaagcc gctgttcaac
     1921 tacttccgcc agctcttcgc gcaggtcacc aacccgccga tcgacccgat ccgcgagcag
     1981 atggtgatgt cgctggtgtc cttcatcggc ccgcgcccca acctgctcga gatcaacgag
     2041 atcaacccgc ccttccgcct cgaggtgagc cagccggtgc tcgacttcga gggcatggcc
     2101 aagatccgca acatcgcgcg ctacacgcag aacaagttcc gctccgccga gctggacatc
     2161 tgctatccgg ccgagtgggg caacgagggc gtcgaggcgc gcctcgcctc gctgtgcgcc
     2221 gacgccgaga acgcggtgct ggcgggcacc aacatcctca tcgtctccga ccgcaagctc
     2281 gccgccgacc gcgtcgccat ccccgcgctg ctggcgctgt ccgcgatcca ccagcacctg
     2341 gtggagaagg gcctgcgcac ccgcaccggc ctggtggtgg agaccggctc ggcacgcgag
     2401 gtgcatcact tcgcggtgct cgccggctac ggcgcggaag ccgtgcaccc ctacctcgcg
     2461 ctcgagaccc tggctcacct ggccgacgac gccgaggccg cggccaagta cgtcaagcac
     2521 ttcgtcaagg cgatcggcaa gggcctgatg aaggtcatgt cgaagatggg catctcgacc
     2581 tac
//
LOCUS       DAOTIN010000222         2387 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_52728_length_2387_cov_7.920240, whole genome shotgun sequence.
ACCESSION   DAOTIN010000222 DAOTIN010000000
VERSION     DAOTIN010000222.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 2387)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2387)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2387
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_52728_length_2387_cov_7.920240"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..461)
                     /locus_tag="P5537_16910"
     CDS             complement(<1..461)
                     /locus_tag="P5537_16910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0048472 - threonine-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HRV79769.1"
                     /translation="MSLSLLLVLAVKMAAGLLADRVFGEARRFHPLVGFGRWAGWVEQ
                     VCRQLFFGTSETGMRLAGLLAWALAVLPWVALALWLRALHPQAHWVVDSALLYFALGG
                     RSLAEHAQAVATPLAAGELDAARERVGWIVSRDTRALDTEGVARAATESVL"
     gene            604..2142
                     /locus_tag="P5537_16915"
     CDS             604..2142
                     /locus_tag="P5537_16915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012586095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HRV79770.1"
                     /translation="MSSPITLMVQGTTSDAGKSTLVAGLARCLRRRGLRVAPFKPQNM
                     ALNSAVTVDGGEIGRAQALQALAAGVAPHTDFNPVLLKPSTDIGAQVIIHGRAVASLS
                     ARDYHAYKPTAMAAVMQSWDRLCSGYEAVLVEGAGSPAEINLRDRDIANMGFAEAADV
                     PVVLVADIDRGGVFAHLVGTLELLSPSEQARVKGFVINRFRGDLGLLQSGLDWLEART
                     GRPVFGVLPYLHGLFLDAEDALADSAADVRAGEAALRVIAPVYSRISNHTDLDPLRLH
                     PQVDFRWIGPGQAIPPADLIVLPGSKSVQADLAWLRAQGWEAAIRRHLRYGGKVIGIC
                     GGFQMLGRELADPLGLEGAPGTMAGLGLLEVATVLEQRKQLRNLRGRLANLSRHDGSD
                     AEPGLGADVTGYEIHMGVTSGPALARPALWLAQEGDEAAPTRPDGAISADGQLLGTYV
                     HGLFDAPAALSALLAWAGLDAQALEGAGAVDLAARREADLDRLADAIEAHVDLAALFA
                     PDRI"
     gene            2161..>2387
                     /locus_tag="P5537_16920"
     CDS             2161..>2387
                     /locus_tag="P5537_16920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HRV79771.1"
                     /translation="MNPDTPRRHGAEESLLGQAVAYRDTYAPELLFPIARQLKRDELG
                     LHADALPFVGEDLWNAYELSWLDARGKPVVAL"
BASE COUNT          328 a          913 c          838 g          308 t
ORIGIN      
        1 tccagcaccg actcggtggc cgccctggcc acgccctcgg tgtcgagcgc gcgggtgtcg
       61 cggctcacga tccagcccac ccgctcgcgt gcggcgtcga gctcgcctgc cgcgagcggc
      121 gtcgccactg cctgtgcgtg ctcggccagg ctgcgcccgc cgagcgcgaa gtacagcagc
      181 gcgctgtcca ccacccagtg cgcctgcggg tggagcgcgc gcagccacag cgcgagcgcc
      241 acccagggca gcaccgcgag cgcccaggcg agcagccccg ccaggcgcat gccggtctcg
      301 ctggtgccga agaacagctg gcggcaaacc tgctccaccc agcccgccca gcgcccgaac
      361 ccgaccagcg gatgaaagcg cctcgcctcg ccgaacacgc gatcggcgag caggccggcg
      421 gccatcttga cggcgaggac gaggagcagg gagagcgaca tggcgggtgg gagcggaggg
      481 aagcggggcg ttgcgccggc ccggccggca ggcgccggcg cgcaggggcg cctttgcgca
      541 gcgggcaagg tccgaatcgg cgataattcg gccccttttt gcaacgaggc gggattctac
      601 gcgatgtcct ccccgatcac gctgatggtc cagggcacca cctccgacgc gggcaagagc
      661 acgctcgtcg ccgggctcgc gcgctgcctg cgccggcgcg gcctgcgcgt ggcgccgttc
      721 aagccgcaga acatggcgct caactccgcc gtcacggtcg acggcggcga gatcggccgc
      781 gcccaggcgc tgcaggcgct cgccgccggc gtcgccccgc acaccgactt caacccggtg
      841 ctgctcaagc catccaccga catcggcgcc caggtcatca tccacggccg cgctgtcgcc
      901 agcctgtcgg cgcgcgatta ccacgcctac aagcccaccg cgatggccgc ggtgatgcag
      961 agctgggacc gcctgtgcag cggctacgag gcggtgctgg tcgagggcgc cggaagcccg
     1021 gccgagatca acctgcgcga ccgcgacatc gccaacatgg gtttcgcgga ggctgccgac
     1081 gtgcctgtcg tgctggtcgc cgacatcgac cgcggcggcg tgttcgccca cctcgtcggt
     1141 accctcgagc tgctctcacc ctcggaacag gcgcgggtaa agggcttcgt gatcaaccgc
     1201 ttccgcggcg atctcggcct gctgcagtcc ggcctggact ggctggaggc gcgcaccggg
     1261 cggccggtgt tcggcgtgct gccctacctg cacgggctct tcctcgacgc cgaggacgcg
     1321 ctcgccgaca gcgccgccga cgtgcgcgcg ggcgaggccg cgctgcgcgt gatcgcaccg
     1381 gtgtattcgc gcatctccaa ccacaccgac ctcgacccgc tgcgcctgca cccgcaggtg
     1441 gatttccgct ggatcggccc cgggcaggcg atcccgcccg ccgacctgat cgtgctgccc
     1501 ggctccaaga gcgtgcaggc cgacctcgcc tggctgcgtg cccagggctg ggaggcggcg
     1561 atccgccgcc acctgcgcta cggcggcaag gtgatcggca tctgcggcgg cttccagatg
     1621 ctcggccgcg agctcgccga tccgctcggc ctcgagggcg cgcccggcac gatggccggg
     1681 ctgggcctgc tcgaggtggc gactgtgctc gaacagcgca agcagctgcg caacctgcgc
     1741 ggccggctcg cgaacctgtc gcgccacgac gggtccgatg cggaacctgg gctcggcgcg
     1801 gacgtgaccg gctacgagat ccacatgggc gtcacctccg gcccggcgct ggcgaggccg
     1861 gcactgtggc tggcccagga gggggacgag gccgcgccga cccggcccga cggcgcgatc
     1921 tccgccgacg ggcagctcct cggcacctac gtccacggcc tcttcgacgc ccctgcggcg
     1981 ctgtcggcgc tgctcgcctg ggcggggctg gacgcgcagg cgctggaagg ggctggcgcg
     2041 gtcgatctcg ccgcccgccg cgaggccgat ctcgaccgcc tcgccgacgc gatcgaggcc
     2101 catgtcgacc tggcggccct gttcgccccc gaccggatct gaatgctcgc aggacccacg
     2161 atgaacccag acacgccccg ccgccacggc gcagaagaat ccctgctcgg ccaggcggtc
     2221 gcctaccgcg acacctacgc ccccgagctg ctgttcccga tcgcccgcca gctcaagcgc
     2281 gacgagctcg gcctgcacgc cgacgcgctg cccttcgtcg gcgaggacct gtggaacgcc
     2341 tacgagctct cctggctgga tgcgcgcggc aagccggtgg tggcgct
//
LOCUS       DAOTIN010000223         2019 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_66197_length_2019_cov_5.819246, whole genome shotgun sequence.
ACCESSION   DAOTIN010000223 DAOTIN010000000
VERSION     DAOTIN010000223.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 2019)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2019)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2019
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_66197_length_2019_cov_5.819246"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..416
                     /gene="mutL"
                     /locus_tag="P5537_16925"
     CDS             <1..416
                     /gene="mutL"
                     /locus_tag="P5537_16925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923704.1"
                     /note="This protein is involved in the repair of
                     mismatches in DNA. It is required for dam-dependent
                     methyl-directed DNA mismatch repair. Promotes the
                     formation of a stable complex between two or more
                     DNA-binding proteins in an ATP-dependent manner without
                     itself being part of a final effector complex; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA mismatch repair protein MutL"
                     /protein_id="HRV79772.1"
                     /translation="PAVFSVGAKDMAAAEECTEVLAGMGFEIAAAGPQELVVRSVPAL
                     LASAPVAELVRELLQELREFPATEVVTARRNELLATMACHGAVRANRQLTLPEMNALL
                     RDMEATERADQCNHGRPTWTQLSLAELDRFFMRGQ"
     gene            complement(459..1040)
                     /locus_tag="P5537_16930"
     CDS             complement(459..1040)
                     /locus_tag="P5537_16930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004374908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqaA family protein"
                     /protein_id="HRV79773.1"
                     /translation="MKIFSPLYERAMVWSRHRRAPWFLGGLSFAESSFFPIPPDVMLA
                     PMCLANPHRAWWFALLTTLTSVAGGLFGYLIGYYAFDLIEPWLRGSHYWSAYEQAVAW
                     FDAWGFWAIFIAGFSPIPYKVFTIAAGVASMALLPFTLASLVGRGARFFLVAGLMAWG
                     GERMEGALRKYVDRIGWATVAAVVVGVLVYRAG"
     gene            1473..1988
                     /locus_tag="P5537_16935"
     CDS             1473..1988
                     /locus_tag="P5537_16935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HRV79774.1"
                     /translation="MKKTLAAACIAALLAGGCALPVHQDSAAGIPAAASQRALHSAAH
                     WNGLARDVAQRLSARLAPQTALFVNQHGDASAFDRAFTTQLITALLEVGHPVLRTPAG
                     ALRVGVDTQVKPGIDATGALEVIVSTSVTDSSQFIARETGVFRADAADEALYLAAPQT
                     RSKAFQVVGGE"
BASE COUNT          348 a          756 c          645 g          270 t
ORIGIN      
        1 tcccggcggt gttctcggtg ggggcgaagg acatggcggc ggccgaggag tgcaccgagg
       61 tgctcgccgg catgggcttc gagatcgccg cggccgggcc ccaggagctc gtcgtgcgca
      121 gcgtaccggc gctgctggcg agcgcaccgg tggccgagct ggtgcgagag ctgctgcagg
      181 agctgcgcga attccccgcc accgaggtcg ttaccgcgcg ccgcaacgag ctgctcgcca
      241 ccatggcctg ccacggcgcg gtgcgcgcca accgccagct caccctgccc gagatgaacg
      301 ccctgctgcg cgacatggag gccaccgagc gcgccgacca gtgcaaccac ggccgcccca
      361 cctggacgca gctcagcctg gccgagctcg accgcttctt catgcgcggc caataacgca
      421 cacccggcgc cgatttcgcg ttttccggcg cgcctcaatc atcccgcccg atacaccagc
      481 accccgacca ccaccgccgc gaccgtggcc cagccgatgc ggtcgacgta cttgcgcagc
      541 gcgccctcca tgcgctcgcc gccccaggcc atcagccccg cgaccaggaa gaagcgcgca
      601 ccacgaccga ccagcgaggc cagcgtgaac ggcagcaacg ccatcgacgc cacgccggct
      661 gcgatcgtga acaccttgta ggggatcggc gagaagccgg cgatgaagat cgcccagaag
      721 ccccaggcgt cgaaccacgc taccgcttgc tcgtaggcgc tccagtaatg actcccgcgc
      781 agccagggct cgatgaggtc gaaggcgtag tagccgatca ggtagccgaa gaggcccccg
      841 gcgacggagg tcagcgtggt caggagcgcg aaccaccacg cgcgatgcgg attcgccagg
      901 cacatcggcg cgagcatgac gtccggcggg atcgggaaga aggacgactc ggcaaagctc
      961 agcccaccca ggaaccaggg cgcgcgccga tgccgcgacc acaccatcgc ccgctcgtac
     1021 agcggcgaaa agatcttcac agacacacct cgacaggaat gcacggaccg cccgtgcgca
     1081 gcgggcgcca tgatacccgc agcgcacggg cgttttgaga gcatcaccgc ggcaggttac
     1141 atcccaccgc ggacgagacc ggggcgtcca gcgcccacgg tccgagccgg aagacacgga
     1201 cgatgttttc cccagcgggc gtgagcagct tccgggacaa gctgtggata agtcgtgcaa
     1261 ggcgctggcg agcaagggga ttcccccgct gcccgttttt tgtgcagcaa agcgacgcgg
     1321 tactatgtct cacccgccga cgcggcggaa ttgagtcaga gcggggcttc tgctagcttt
     1381 cggcatagct gcgacatacg ccgtttcact tgcccggtac cattctcgcc ctctgcggcc
     1441 aatgtggtgc ctcgtcccgg agaatgcgct ccatgaagaa gaccctcgcc gcggcctgca
     1501 tcgcggccct gctggcaggc ggctgcgccc tgcccgtcca tcaagactcc gcggccggca
     1561 tccccgccgc tgcctcgcag cgcgcgctgc actccgccgc acactggaac ggcctcgccc
     1621 gcgacgtcgc gcagcgcctg tccgcccgcc tggccccgca gacggcgctg ttcgtcaatc
     1681 agcacggcga cgcgtcggcc ttcgaccgcg ccttcaccac ccagctgatc accgccctgc
     1741 tcgaggtcgg ccatccggtg ctgcgcaccc cggccggtgc cctgcgcgtc ggcgtcgata
     1801 cccaggtcaa gcccggcatc gacgccacgg gtgcgctcga agttatcgtc agcaccagcg
     1861 tgaccgacag cagccagttc atcgcgcgcg agaccggggt gttccgcgcc gatgcggccg
     1921 acgaggcgct ctacctcgcc gccccgcaga cgcgctccaa ggccttccag gtcgtcggag
     1981 gcgaatgatg cgcacgcccg caatcctcgc cgcagccct
//
LOCUS       DAOTIN010000224         1994 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_67306_length_1994_cov_8.612687, whole genome shotgun sequence.
ACCESSION   DAOTIN010000224 DAOTIN010000000
VERSION     DAOTIN010000224.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 1994)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1994)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1994
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_67306_length_1994_cov_8.612687"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..710)
                     /locus_tag="P5537_16940"
     CDS             complement(<1..710)
                     /locus_tag="P5537_16940"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004333792.1"
                     /note="part of NADH-ubiquinone oxidoreductase complex I;
                     shuttles electrons from NADH, via FMN and iron-sulfur
                     (Fe-S) centers, to quinones in the respiratory chain; NuoF
                     is part of the soluble NADH dehydrogenase fragment, which
                     represents the electron input part of NADH dehydrogenase;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit F"
                     /protein_id="HRV79775.1"
                     /translation="MILAGCDGDRTWRLQDYVARGGYSALRKILAEKIPQDAIIAELK
                     TSVLRGRGGAGFPTGLKWSFMPRSFPGDKYLACNSDEGEPGTFKDRDILRYNPHSVIE
                     GMAIAAYAMGAARGYNYIHGEIFETYSRFEEALAEAREAGFIGQSILGSDFSFELFAH
                     HGYGAYICGEETALLESIEGKKGQPRFKPPFPASYGLYGKPTTINNTETFASVPFIMN
                     MGGEAFLNLGKPNNGGMKL"
     gene            complement(722..1201)
                     /gene="nuoE"
                     /locus_tag="P5537_16945"
     CDS             complement(722..1201)
                     /gene="nuoE"
                     /locus_tag="P5537_16945"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004333791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoE"
                     /protein_id="HRV79776.1"
                     /translation="MLSQESLQQIDREIAKYPPDQKQSAVMAALRIAQVEKGWLPKEL
                     IEFVARYLGMPPIAAFEVASFYNMYDLAPVGRHKITVCTNLPCALSGGVHAADYIKEK
                     LGIDFNETTPDGKFTLKEGECMGACGDAPVLLVNNHHMCSWMTTEKIDQMLAELDKK"
     gene            complement(1290..>1994)
                     /locus_tag="P5537_16950"
     CDS             complement(1290..>1994)
                     /locus_tag="P5537_16950"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015436667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA];
                     GO_function: GO:0048038 - quinone binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit D"
                     /protein_id="HRV79777.1"
                     /translation="LNANREGSMLDFLEDFTNRFPTYCDEYETLLTDNRIWKQRTVGI
                     GVVSPEQALAWGFTGPMLRGSGIAWDLRKKQPYEVYDQVDFDVPIGKNGDCYDRYLCR
                     MEEMRQSNRIIKQCIDWLRKNPGPVITDNHKVAPPSREAMKTNMEELIHHFKLFTEGM
                     HVPKGEVYAAVEHPKGEFGVYAVSDGANKPYRLKLRAPGFAHLAAMDDIARGHMIADV
                     VAIIGTMDVVFGEIDR"
BASE COUNT          304 a          625 c          660 g          405 t
ORIGIN      
        1 agcttcatgc cgccgttgtt gggcttgccg aggttcagga aggcctcgcc gcccatgttc
       61 atgatgaacg ggacggacgc gaaggtctcg gtgttgttga tcgtggtcgg cttgccatag
      121 aggccgtagc tcgccgggaa aggcggcttg aagcgcggct ggcctttctt gccctcgatc
      181 gactcgagca gcgcggtctc ctcgccacag atgtaggcgc cgtagccgtg gtgcgcgaag
      241 agctcgaagg agaagtcgct gccgaggatg ctctggccga tgaagcccgc ctcgcgcgcc
      301 tcggcgagcg cctcctcgaa gcgcgagtag gtctcaaaga tctcgccgtg gatgtagttg
      361 tagccacgcg cggcgcccat cgcgtaggcg gcgatcgcca tgccctcgat gacgctgtgc
      421 gggttgtagc gcaggatgtc gcggtccttg aaggtccccg gctcgccctc gtcggagttg
      481 cacgcgaggt acttgtcgcc agggaaggag cgcggcatga agctccactt caggccggtc
      541 gggaaacccg caccgccacg gccgcgcagc accgaggtct tgagctcggc gatgatcgcg
      601 tcctgcggga tcttctcggc gaggatcttg cggagcgccg agtagccgcc gcgggcgacg
      661 tagtcctgga gccgccaggt gcggtcgccg tcgcagccgg cgaggatcat tccttgcgtg
      721 ctcatttctt gtccagctcg gccagcatct ggtcgatctt ctcggtggtc atccagctgc
      781 acatgtgatg gttattcacc agcagcaccg gggcgtcgcc acaggcgccc atgcactcgc
      841 cttccttcag cgtgaacttg ccgtcgggcg tcgtctcgtt gaagtcgatg ccgagctttt
      901 ccttgatgta gtccgcggcg tggacaccgc cggagagcgc acacggcagg ttggtgcaca
      961 cggtgatctt gtgccgtccg accggcgcga ggtcgtacat gttgtagaag ctcgcgacct
     1021 cgaaggccgc aatcggcggc atgccgaggt acctggccac gaactcgatg agttccttgg
     1081 gcaaccagcc cttctcgacc tgcgcgatcc gcagcgcggc catgaccgcg gactgctttt
     1141 gatcgggcgg atacttggcg atctctcgat cgatctgttg cagcgattcc tggctcagca
     1201 tgtcgtcttg atcttccgga tagcctgccg attcttgttt gataccgcgg cgcccgcagg
     1261 cgcccatccg ctgttgcgcg cgggcgcgct cagcggtcga tctcgccgaa caccacgtcc
     1321 atcgtgccga tgatcgcgac cacgtcggca atcatgtggc cacgggcgat gtcgtccatc
     1381 gccgcgaggt gcgcgaagcc cggcgcgcgc agcttcagcc ggtagggctt gttcgccccg
     1441 tccgacaccg catacacgcc gaactcgccc ttgggatgct cgaccgctgc gtacacctcg
     1501 cccttgggca cgtgcatgcc ttcggtgaag agcttgaagt ggtggatcag ctcttccatg
     1561 ttggtcttca tcgcctcgcg agaaggcggc gcgaccttgt ggttgtcggt gatgaccggg
     1621 ccggggttct tgcgcagcca gtcgatgcac tgcttgatga tccggttcga ctggcgcatc
     1681 tcttccatgc ggcacaagta acggtcgtag cagtcgccgt tcttgccgat cggcacgtcg
     1741 aagtcgacct gatcgtagac ctcgtagggc tgcttcttgc gcaggtccca ggcgatgccc
     1801 gagccgcgca gcatcgggcc ggtgaagccc caggccagcg cctgctccgg agacaccacg
     1861 ccgatgccga cggtgcgctg cttccagatg cggttgtcgg tcagcagggt ctcgtattcg
     1921 tcgcagtagg tcgggaagcg gttggtgaag tcctcgagga agtcgagcat cgagccttcg
     1981 cggttggcgt tgag
//
LOCUS       DAOTIN010000225         1887 bp    DNA     linear   ENV 11-JUN-2024
DEFINITION  MAG TPA_asm: Thauera sp. isolate AMR_MDS_3024
            NODE_72616_length_1887_cov_10.183952, whole genome shotgun
            sequence.
ACCESSION   DAOTIN010000225 DAOTIN010000000
VERSION     DAOTIN010000225.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN33868048
            Sequence Read Archive: SRR5007144
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Thauera sp. (wastewater metagenome)
  ORGANISM  Thauera sp.
            Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
            Zoogloeaceae; Thauera.
REFERENCE   1  (bases 1 to 1887)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1887)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2023 13:28:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,393
            CDSs (total)                      :: 3,348
            Genes (coding)                    :: 3,329
            CDSs (with protein)               :: 3,329
            Genes (RNA)                       :: 45
            tRNAs                             :: 41
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 3 of 19
            Pseudo Genes (incomplete)         :: 17 of 19
            Pseudo Genes (internal stop)      :: 2 of 19
            Pseudo Genes (multiple problems)  :: 2 of 19
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1887
                     /organism="Thauera sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_72616_length_1887_cov_10.183952"
                     /isolate="AMR_MDS_3024"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1905334"
                     /environmental_sample
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.28 N 114.17 E"
                     /collection_date="2014-12-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..404)
                     /locus_tag="P5537_16955"
     CDS             complement(<1..404)
                     /locus_tag="P5537_16955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="HRV79778.1"
                     /translation="MSTKLQYLADAHNARFGTSGVRGLVTDLSDAVCYAYAQAFLRSV
                     AAASPRIVVGHDLRPSSPRIAAACIQAIRDAGHEAIFVGALPTPALAYYCALHGAAGI
                     VVTGSHIPFDRNGIKFYRADGEIDKADEQAIL"
     gene            complement(817..1380)
                     /locus_tag="P5537_16960"
     CDS             complement(817..1380)
                     /locus_tag="P5537_16960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Uma2 family endonuclease"
                     /protein_id="HRV79779.1"
                     /translation="MALPQPAARFERADFFAWEAEQPMKHDYVAGEVFAQAGARQDHV
                     VVALNIATSLRQKLRGTPCRAYISDMQLEVVQADAVFYPDVMVSCHPEDLAAERVLHH
                     PRVIIEVLSDSTAAYDRGAKFAAVRMLDSLQEYALVDPERRSVEIFRRLPSNDWLLAT
                     GDSARGLVLAALELEIGLDEVFEDVGA"
     gene            1550..>1887
                     /locus_tag="P5537_16965"
     CDS             1550..>1887
                     /locus_tag="P5537_16965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004356845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Uma2 family endonuclease"
                     /protein_id="HRV79780.1"
                     /translation="MALPKLKSEFDVDAYMAWEEDQPERHEYLGGEVFAMSGGTDAHY
                     TILLNTATSLKVALSGKPCRAFLSGMKLRVDRADAVFYPDVFVTCDPRDRQPEASLAK
                     QHPALIIEVLS"
BASE COUNT          327 a          638 c          633 g          289 t
ORIGIN      
        1 tcgaggatgg cctgctcgtc cgccttgtcg atctcgccgt cggcacggta gaacttgatg
       61 ccgttgcggt cgaaggggat gtggctgccg gtaacgacga tgcccgcggc gccgtgcagc
      121 gcgcagtagt aggccagcgc gggcgtgggc agggcgccga caaaaatcgc ctcgtgcccg
      181 gcgtcgcgga tcgcctggat gcaggccgcg gcgatgcgcg ggctgctggg gcgtaggtcg
      241 tggccgacga cgatgcgcgg gctggcggcg gcgacgctgc gcaggaaggc ctgcgcgtag
      301 gcgtagcaga ccgcatcaga cagatcggtg acgaggccgc gcacgccgct ggtgccgaag
      361 cgggcgttat gggcgtcggc gaggtattgg agttttgtgc tcatagggag tgggaaaaaa
      421 gagctaaaag aatgaatctc gcgcccgccg ccccgggccc gcgaggtttt tttgtaggag
      481 cgccggcagg cgcgaacgca gcctccgaat aaccgcgccg cccaacgcaa ccgcagcctt
      541 cccgccttct gccgctccag cgcaaaacga aagcgcaccg tctcatgtag gagcgccggc
      601 aggcgcgaac acggcggcgc agcattcggc gcattggcac gatccgacgg ctgcattcgc
      661 gcctgccggc gctcctacac aagccgccgc ggacccgttg cccctgcagg agcgcgggca
      721 ggcgcgaatg cagcctccga ataaccgcat caacgcaacc acagccttcc cgccttccgc
      781 cactcccaca cggaacggaa gcgcacccgt tgcgtgtcag gcgccgacgt cctcgaacac
      841 ctcgtccagc ccgatctcca gctccagcgc cgccagcacc aggccgcgcg cgctgtcgcc
      901 ggtggcgagc agccagtcgt tggagggcag gcggcggaag atctcgacgc tgcgtcgctc
      961 gggatcgacc agcgcgtatt cctgcaggct gtcgagcatg cgaaccgcgg cgaacttggc
     1021 accgcggtcg taggcggcgg tgctgtcgct caacacctcg atgatcacgc gcggatgatg
     1081 cagcacgcgc tcggcggcga ggtcttcggg gtggcagctc accatcacgt cggggtagaa
     1141 cactgcatcg gcctgcacca cctcgagctg catgtcggag atgtaggccc ggcagggcgt
     1201 gccgcgcagc ttctggcgca gcgaggtggc gatgttgagt gccacgacca catgatcctg
     1261 ccgtgccccg gcctgggcga acacctcgcc ggcgacgtag tcgtgcttca tgggctgttc
     1321 ggcctcccag gcgaagaaat ccgcgcgttc gaagcgcgcg gcgggttgag gcaaggccat
     1381 gatgggcgag ctcccgatcc gtgagatggc tgaagtctag cagggtgagg gcgggctgct
     1441 cgatgggcgc cgcgggccgc ggcgcggccg tgagcaaatg aaagacctga ccccggtttt
     1501 ctttcccaaa tcgacccgct atgctcgacc aaacgaagga gttccgacta tggccctgcc
     1561 caagctcaaa tccgaattcg acgtcgacgc ctacatggcc tgggaagagg atcagcccga
     1621 acgtcacgag tacctcggcg gcgaggtctt cgccatgtcc ggcggcacgg atgcgcatta
     1681 cacgatcctg ctcaacaccg cgacgagcct taaggtcgca ctctccggca agccctgccg
     1741 cgccttcctc tccggcatga agctgcgcgt cgaccgcgcc gacgccgtct tctaccccga
     1801 tgtcttcgtc acctgcgacc cgcgcgaccg ccagcccgag gccagcctgg ccaagcagca
     1861 cccggcgctg atcatcgagg tcctctc
//
